Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000888-TA|BGIBMGA000888-PA|IPR003599|Immunoglobulin
subtype, IPR003598|Immunoglobulin subtype 2, IPR003961|Fibronectin,
type III, IPR013098|Immunoglobulin I-set, IPR013151|Immunoglobulin,
IPR007110|Immunoglobulin-like, IPR008957|Fibronectin, type III-like
fold
(1207 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein. 508 e-143
DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein. 508 e-143
AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein. 508 e-143
AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein. 500 e-140
BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein. 494 e-139
BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein. 493 e-138
BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein. 492 e-138
AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein... 436 e-121
AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens ... 434 e-121
AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens ... 289 3e-77
BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein pr... 242 6e-63
AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein. 206 3e-52
BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA seq... 206 5e-52
AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA seq... 206 5e-52
AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA seq... 206 5e-52
AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA seq... 206 5e-52
AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA seq... 206 5e-52
AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA seq... 206 5e-52
AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA seq... 206 5e-52
AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA seq... 206 5e-52
AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein. 204 2e-51
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 201 1e-50
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 201 1e-50
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 201 1e-50
AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein. 179 6e-44
AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein. 178 9e-44
AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein. 178 9e-44
AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhe... 176 5e-43
AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhe... 176 5e-43
AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhe... 176 5e-43
AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhe... 176 5e-43
AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhe... 176 5e-43
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 174 1e-42
X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein. 170 2e-41
M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorecta... 170 2e-41
X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor ... 169 4e-41
X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal glycopro... 169 4e-41
BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal) pr... 169 4e-41
AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal) pr... 169 4e-41
U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein. 168 9e-41
BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1 (chi... 168 9e-41
AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens ... 168 9e-41
U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein. 168 1e-40
BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein. 167 3e-40
AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein. 167 3e-40
AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein. 167 3e-40
AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1... 165 8e-40
AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhe... 164 1e-39
AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhe... 164 1e-39
AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein. 164 1e-39
AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein pr... 163 5e-39
BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein. 162 6e-39
BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell ... 162 6e-39
BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell ... 162 6e-39
AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein. 162 6e-39
AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecul... 162 6e-39
AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhe... 160 2e-38
AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhe... 160 2e-38
Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein. 159 7e-38
U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor p... 159 7e-38
U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor p... 159 7e-38
BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein. 159 7e-38
AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein. 157 3e-37
AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608 pr... 156 5e-37
BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein. 155 9e-37
AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens ... 148 1e-34
BC111748-1|AAI11749.1| 1007|Homo sapiens roundabout homolog 4, m... 146 3e-34
BC111562-1|AAI11563.1| 1007|Homo sapiens roundabout homolog 4, m... 146 3e-34
BC039602-1|AAH39602.1| 1007|Homo sapiens roundabout homolog 4, m... 146 3e-34
AY358083-1|AAQ88450.1| 1004|Homo sapiens magic roundabout protein. 146 3e-34
AF361473-1|AAL31867.1| 1007|Homo sapiens magic roundabout protein. 146 3e-34
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 146 3e-34
U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor pr... 146 4e-34
BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein. 146 4e-34
BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine k... 146 4e-34
AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine k... 146 4e-34
AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor ... 146 4e-34
AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor ... 146 4e-34
AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase... 146 4e-34
AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion mo... 146 4e-34
U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4 ... 145 1e-33
Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion mole... 143 3e-33
M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteogly... 143 3e-33
M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule... 143 3e-33
M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1... 143 3e-33
BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AK027852-1|BAB55411.1| 792|Homo sapiens protein ( Homo sapiens ... 143 3e-33
AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecu... 143 3e-33
AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteog... 143 4e-33
AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteog... 143 4e-33
AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteog... 143 4e-33
AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine k... 142 5e-33
AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-speci... 142 7e-33
EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein. 142 9e-33
AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein. 141 1e-32
X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein. 141 2e-32
X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane h... 140 3e-32
X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion mole... 136 5e-31
BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein. 135 8e-31
BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein. 135 8e-31
AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein. 135 8e-31
BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein. 133 3e-30
AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog (ch... 133 3e-30
AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog (ch... 133 3e-30
AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog (ch... 133 3e-30
AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog (ch... 133 3e-30
AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog (ch... 133 3e-30
AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein. 133 3e-30
AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related c... 131 2e-29
AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related c... 131 2e-29
AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein. 129 5e-29
AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens ... 129 7e-29
U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor p... 127 3e-28
BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein. 126 4e-28
BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein. 126 5e-28
AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens ... 126 5e-28
AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens ... 126 5e-28
AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein. 126 5e-28
BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine phosph... 122 8e-27
AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine phosph... 122 8e-27
X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for ... 122 1e-26
S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein. 122 1e-26
AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion mo... 122 1e-26
BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion mo... 121 2e-26
U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion prot... 120 3e-26
BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein pr... 120 3e-26
U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion mole... 120 4e-26
DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecu... 119 6e-26
BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein. 119 7e-26
U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein. 117 3e-25
U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein. 117 3e-25
BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein. 117 3e-25
AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor ... 117 3e-25
Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -... 116 4e-25
BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine phosph... 116 4e-25
AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine phosp... 116 4e-25
AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine phosph... 116 4e-25
AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein. 116 4e-25
AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein. 116 4e-25
AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog (ch... 116 7e-25
AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant... 116 7e-25
AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein. 116 7e-25
BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion mo... 114 2e-24
BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein. 114 2e-24
AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog (ch... 114 2e-24
AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens ... 112 6e-24
BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein. 112 8e-24
AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, recep... 112 8e-24
AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, recep... 112 8e-24
AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, recep... 112 8e-24
AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, recep... 112 8e-24
AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosin... 112 8e-24
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 111 1e-23
U35234-1|AAC50299.1| 1948|Homo sapiens protein tyrosine phosphat... 111 1e-23
BC114435-1|AAI14436.1| 1264|Homo sapiens Cdon homolog (mouse) pr... 111 1e-23
BC098583-1|AAH98583.1| 1287|Homo sapiens Cdon homolog (mouse) pr... 111 1e-23
AY424270-1|AAR29062.1| 1914|Homo sapiens myosin lignt chain poly... 111 1e-23
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 111 1e-23
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 111 1e-23
AB050468-1|BAB40659.1| 1094|Homo sapiens membrane glycoprotein L... 111 1e-23
AY730707-1|AAU44786.1| 1093|Homo sapiens leucine-rich repeat pro... 111 1e-23
AF381545-1|AAK62357.1| 1093|Homo sapiens membrane glycoprotein L... 111 1e-23
AF004841-1|AAC34901.2| 1264|Homo sapiens CDO protein. 111 1e-23
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 109 8e-23
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 109 8e-23
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 109 8e-23
AL163282-1|CAB90436.1| 812|Homo sapiens human CHD2-52 down synd... 109 8e-23
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 109 8e-23
AL049946-1|CAB43220.1| 584|Homo sapiens hypothetical protein pr... 108 1e-22
AF531871-1|AAN04865.1| 1014|Homo sapiens transmembrane receptor ... 108 1e-22
AL360004-4|CAI16954.2| 746|Homo sapiens novel protein similar t... 108 1e-22
BC106715-1|AAI06716.1| 1505|Homo sapiens PTPRD protein protein. 107 2e-22
BC106714-1|AAI06715.1| 1506|Homo sapiens PTPRD protein protein. 107 2e-22
L38929-1|AAC41749.1| 1912|Homo sapiens protein tyrosine phosphat... 107 3e-22
BC106713-1|AAI06714.1| 1505|Homo sapiens PTPRD protein protein. 107 3e-22
AL590397-1|CAH73128.2| 1912|Homo sapiens protein tyrosine phosph... 107 3e-22
AL583805-2|CAH70443.2| 1912|Homo sapiens protein tyrosine phosph... 107 3e-22
AL445926-1|CAH73847.2| 1912|Homo sapiens protein tyrosine phosph... 107 3e-22
AL356584-1|CAI16146.2| 1912|Homo sapiens protein tyrosine phosph... 107 3e-22
AL137125-1|CAH70912.2| 1912|Homo sapiens protein tyrosine phosph... 107 3e-22
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 106 4e-22
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 106 4e-22
BC106716-1|AAI06717.1| 1496|Homo sapiens PTPRD protein protein. 106 4e-22
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 106 4e-22
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 106 4e-22
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 106 4e-22
AK074921-1|BAC11295.1| 697|Homo sapiens protein ( Homo sapiens ... 106 4e-22
BC026119-1|AAH26119.1| 697|Homo sapiens contactin 4 protein. 106 6e-22
AB211400-1|BAE79816.1| 1912|Homo sapiens protein tyrosine phosph... 106 6e-22
AC007567-1|AAS07434.1| 383|Homo sapiens unknown protein. 105 1e-21
AB208869-1|BAD92106.1| 1478|Homo sapiens protein tyrosine phosph... 105 1e-21
AY358147-1|AAQ88514.1| 953|Homo sapiens UNC5D protein. 103 5e-21
AB055056-1|BAB83663.1| 948|Homo sapiens KIAA1777 protein (Unc5h... 103 5e-21
X58776-1|CAB37831.1| 824|Homo sapiens cell adhesion molecule L1... 102 7e-21
AK097578-1|BAC05109.1| 600|Homo sapiens protein ( Homo sapiens ... 102 7e-21
BC029119-1|AAH29119.1| 364|Homo sapiens NCAM1 protein protein. 102 9e-21
BC109098-1|AAI09099.1| 783|Homo sapiens MUSK protein protein. 100 3e-20
AY358742-1|AAQ89102.1| 708|Homo sapiens LRMR5827 protein. 100 3e-20
AY358351-1|AAQ88717.1| 945|Homo sapiens GARS1883 protein. 100 3e-20
AY126437-1|AAM95701.1| 934|Homo sapiens transmembrane receptor ... 100 3e-20
AL359832-2|CAI16738.1| 934|Homo sapiens unc-5 homolog B (C. ele... 100 3e-20
AL359832-1|CAI16737.1| 945|Homo sapiens unc-5 homolog B (C. ele... 100 3e-20
AL359384-3|CAI16090.1| 934|Homo sapiens unc-5 homolog B (C. ele... 100 3e-20
AL359384-2|CAI16089.1| 945|Homo sapiens unc-5 homolog B (C. ele... 100 3e-20
AB096256-1|BAC57998.1| 945|Homo sapiens p53-regulated receptor ... 100 3e-20
AF002246-1|AAB60937.1| 1224|Homo sapiens neural cell adhesion mo... 99 5e-20
AL513485-5|CAI14605.1| 1179|Homo sapiens immunoglobulin superfam... 99 8e-20
AB037776-1|BAA92593.1| 1189|Homo sapiens KIAA1355 protein protein. 99 8e-20
BC066363-1|AAH66363.1| 1805|Homo sapiens SDK2 protein protein. 98 2e-19
AY358328-1|AAQ88694.1| 1115|Homo sapiens BOC protein. 98 2e-19
AY027658-1|AAK14795.1| 1114|Homo sapiens brother of CDO protein. 98 2e-19
AL049553-2|CAI20461.1| 957|Homo sapiens MAM domain containing g... 97 4e-19
AY305302-1|AAP72167.1| 583|Homo sapiens kin of irregular chiasm... 96 8e-19
AF478693-1|AAM77220.1| 955|Homo sapiens glycosyl-phosphatidyl-i... 96 8e-19
AB209412-1|BAD92649.1| 1130|Homo sapiens neogenin homolog 1 vari... 96 8e-19
AC005338-1|AAC27825.1| 475|Homo sapiens PTPsigma, partial CDS p... 94 3e-18
BC041156-1|AAH41156.1| 597|Homo sapiens UNC5C protein protein. 93 7e-18
AL117666-1|CAB56036.1| 483|Homo sapiens hypothetical protein pr... 92 1e-17
BC064925-1|AAH64925.1| 688|Homo sapiens KIRREL2 protein protein. 92 1e-17
EF063638-1|ABO42328.1| 1896|Homo sapiens obscurin-like 1 isoform... 91 2e-17
EF063637-1|ABO42327.1| 1544|Homo sapiens obscurin-like 1 isoform... 91 2e-17
BC007201-1|AAH07201.1| 1044|Homo sapiens OBSL1 protein protein. 91 2e-17
AF055634-1|AAC67491.1| 931|Homo sapiens transmembrane receptor ... 91 2e-17
AC098584-1|AAY41022.1| 506|Homo sapiens unknown protein. 91 2e-17
AK131380-1|BAD18531.1| 301|Homo sapiens protein ( Homo sapiens ... 91 2e-17
AY424269-1|AAR29061.1| 1845|Homo sapiens myosin light chain poly... 90 5e-17
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 90 5e-17
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 90 5e-17
AY603755-1|AAT80901.1| 3094|Homo sapiens striated muscle prefere... 88 2e-16
AY305301-1|AAP72166.1| 633|Homo sapiens kin of irregular chiasm... 88 2e-16
AK074163-1|BAB84989.1| 702|Homo sapiens FLJ00236 protein protein. 87 3e-16
AB177856-1|BAD66834.1| 1484|Homo sapiens LAR splice variant 1 pr... 87 3e-16
AY369208-1|AAQ73312.1| 956|Homo sapiens MAM domain-containing g... 87 4e-16
BC012102-1|AAH12102.1| 347|Homo sapiens PTPRF protein protein. 86 8e-16
AL583862-13|CAI14896.1| 347|Homo sapiens protein tyrosine phosp... 86 8e-16
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 85 1e-15
AL583862-11|CAM12884.1| 262|Homo sapiens protein tyrosine phosp... 85 1e-15
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 85 1e-15
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 85 1e-15
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 85 1e-15
DQ234351-1|ABB29980.1| 262|Homo sapiens protein tyrosine phosph... 85 1e-15
X73114-1|CAA51545.1| 1123|Homo sapiens slow MyBP-C protein. 85 2e-15
BC117217-1|AAI17218.1| 1120|Homo sapiens MYBPC1 protein protein. 85 2e-15
BC092418-1|AAH92418.1| 1123|Homo sapiens myosin binding protein ... 85 2e-15
BC046109-1|AAH46109.1| 459|Homo sapiens PTK7 protein protein. 85 2e-15
BC013867-1|AAH13867.2| 510|Homo sapiens PALLD protein protein. 84 3e-15
AF531870-1|AAN04864.1| 940|Homo sapiens transmembrane receptor ... 84 3e-15
AF464873-1|AAL69964.1| 1106|Homo sapiens myoneurin protein. 84 3e-15
AB023209-1|BAA76836.1| 772|Homo sapiens KIAA0992 protein protein. 84 3e-15
X66276-1|CAA46987.1| 1138|Homo sapiens C protein protein. 83 4e-15
BC033727-1|AAH33727.1| 364|Homo sapiens Unknown (protein for IM... 83 4e-15
AL513485-4|CAI14606.1| 1163|Homo sapiens immunoglobulin superfam... 83 6e-15
BC030141-1|AAH30141.1| 1163|Homo sapiens immunoglobulin superfam... 83 8e-15
BC005376-1|AAH05376.1| 498|Homo sapiens myotilin protein. 83 8e-15
AF151909-1|AAD34146.1| 404|Homo sapiens CGI-151 protein protein. 83 8e-15
AF144477-1|AAD44754.1| 498|Homo sapiens myotilin protein. 83 8e-15
AF133820-1|AAD29051.2| 498|Homo sapiens titin-like protein prot... 83 8e-15
AK090455-1|BAC03436.1| 931|Homo sapiens FLJ00376 protein protein. 82 1e-14
EF043567-1|ABK34282.1| 355|Homo sapiens neurotrimin variant 3 p... 81 2e-14
BC050716-1|AAH50716.1| 316|Homo sapiens HNT protein protein. 81 2e-14
AY358331-1|AAQ88697.1| 344|Homo sapiens HNT protein. 81 2e-14
AY358125-1|AAQ88492.1| 937|Homo sapiens MAM-domain protein prot... 81 2e-14
AF126426-1|AAF37591.1| 344|Homo sapiens neurotrimin protein. 81 2e-14
BC048416-1|AAH48416.1| 353|Homo sapiens PTPRF protein protein. 79 7e-14
AL591423-1|CAM13086.1| 1263|Homo sapiens chromosome 9 open readi... 79 7e-14
AL583862-12|CAI14897.1| 353|Homo sapiens protein tyrosine phosp... 79 7e-14
AL353895-2|CAM20931.1| 1263|Homo sapiens chromosome 9 open readi... 79 7e-14
AL158150-4|CAM14352.1| 1263|Homo sapiens chromosome 9 open readi... 79 7e-14
X51602-1|CAA35946.1| 1338|Homo sapiens protein ( Human flt mRNA ... 78 2e-13
L34774-1|AAA36387.1| 345|Homo sapiens opioid-binding cell adhes... 78 2e-13
BX537377-1|CAD97619.1| 338|Homo sapiens hypothetical protein pr... 78 2e-13
BC126251-1|AAI26252.1| 345|Homo sapiens opioid binding protein/... 78 2e-13
BC117254-1|AAI17255.1| 345|Homo sapiens opioid binding protein/... 78 2e-13
BC074773-1|AAH74773.1| 345|Homo sapiens opioid binding protein/... 78 2e-13
AL139005-1|CAI17096.1| 1338|Homo sapiens fms-related tyrosine ki... 78 2e-13
AL138712-1|CAI14846.1| 1338|Homo sapiens fms-related tyrosine ki... 78 2e-13
AJ277892-1|CAD12455.1|26926|Homo sapiens N2B-Titin Isoform protein. 78 2e-13
AF063657-1|AAC16449.2| 1338|Homo sapiens vascular endothelial gr... 78 2e-13
X90568-1|CAA62188.1|26926|Homo sapiens titin protein. 78 2e-13
AL590103-6|CAI12129.1| 188|Homo sapiens heparan sulfate proteog... 78 2e-13
Y13901-1|CAA74200.1| 802|Homo sapiens fibroblast growth factor ... 77 3e-13
L03840-1|AAB59389.1| 802|Homo sapiens fibroblast growth factor ... 77 3e-13
EF571596-1|ABQ01235.1| 802|Homo sapiens fibroblast growth facto... 77 3e-13
BC107797-1|AAI07798.1| 179|Homo sapiens TTN protein protein. 77 3e-13
BC011847-1|AAH11847.1| 802|Homo sapiens fibroblast growth facto... 77 3e-13
AY358128-1|AAQ88495.1| 717|Homo sapiens IGSF9 protein. 77 3e-13
AF487555-1|AAM13666.1| 802|Homo sapiens fibroblast growth facto... 77 3e-13
AB209631-1|BAD92868.1| 1034|Homo sapiens Fibroblast growth facto... 77 3e-13
X68264-1|CAA48332.1| 646|Homo sapiens melanoma associated glyco... 77 4e-13
M29277-1|AAA20824.1| 646|Homo sapiens MUC18 glycoprotein protein. 77 4e-13
M28882-1|AAA20922.1| 646|Homo sapiens MUC18 glycoprotein protein. 77 4e-13
AL832379-1|CAD91155.1| 1045|Homo sapiens hypothetical protein pr... 77 4e-13
AL832002-1|CAD89906.1| 1320|Homo sapiens hypothetical protein pr... 77 4e-13
AL512429-2|CAH73748.1| 1320|Homo sapiens sarcomeric protein myop... 77 4e-13
AL512429-1|CAH73747.1| 1045|Homo sapiens sarcomeric protein myop... 77 4e-13
AF328296-1|AAK50625.1| 1320|Homo sapiens myopalladin protein. 77 4e-13
X57205-1|CAA40490.1| 802|Homo sapiens fibroblast growth factor ... 77 5e-13
AL834247-1|CAD38923.2| 1391|Homo sapiens hypothetical protein pr... 77 5e-13
AF202063-1|AAF27432.1| 762|Homo sapiens fibroblast growth facto... 77 5e-13
BC112138-1|AAI12139.1| 435|Homo sapiens CADM2 protein protein. 76 7e-13
BC112136-1|AAI12137.1| 435|Homo sapiens CADM2 protein protein. 76 7e-13
BC074742-1|AAH74742.1| 344|Homo sapiens opioid binding protein/... 76 7e-13
BC056418-1|AAH56418.1| 646|Homo sapiens melanoma cell adhesion ... 76 7e-13
BC034671-1|AAH34671.1| 702|Homo sapiens carcinoembryonic antige... 76 7e-13
AB209925-1|BAD93162.1| 659|Homo sapiens Melanoma cell adhesion ... 76 7e-13
X69490-1|CAA49245.1| 4650|Homo sapiens titin protein. 76 9e-13
X64697-1|CAA45938.1| 3100|Homo sapiens titin protein. 76 9e-13
M29540-1|AAA51967.1| 702|Homo sapiens CEA protein. 76 9e-13
M17303-1|AAB59513.1| 702|Homo sapiens CEA protein. 76 9e-13
M15042-1|AAA51963.1| 698|Homo sapiens CEA protein. 76 9e-13
X16455-1|CAA34474.1| 697|Homo sapiens pCEA80-11 protein (647 AA... 75 1e-12
AJ277892-4|CAD12458.1| 1294|Homo sapiens Titin Novex-2 Isoform p... 75 1e-12
AF005070-1|AAB61615.1| 348|Homo sapiens neural cell adhesion mo... 75 2e-12
BC109193-1|AAI09194.1| 757|Homo sapiens KIRREL protein protein. 75 2e-12
BC109192-1|AAI09193.1| 757|Homo sapiens KIRREL protein protein. 75 2e-12
BC101801-1|AAI01802.1| 778|Homo sapiens kin of IRRE like 3 prot... 75 2e-12
BC101775-1|AAI01776.1| 778|Homo sapiens kin of IRRE like 3 (Dro... 75 2e-12
AY358743-1|AAQ89103.1| 600|Homo sapiens NEPH2 protein. 75 2e-12
AY017369-1|AAK00529.1| 605|Homo sapiens NEPH1 protein. 75 2e-12
AL139010-1|CAH73881.1| 757|Homo sapiens kin of IRRE like (Droso... 75 2e-12
AL137357-1|CAB70709.1| 1185|Homo sapiens hypothetical protein pr... 75 2e-12
AF538973-1|AAN16368.1| 437|Homo sapiens nectin-like protein 3 p... 75 2e-12
AF480410-1|AAN73042.1| 778|Homo sapiens NPEH2 protein. 75 2e-12
AF363368-1|AAM60750.1| 388|Homo sapiens TSLC1-like 2 protein. 75 2e-12
AB058770-1|BAB47496.1| 779|Homo sapiens KIAA1867 protein protein. 75 2e-12
AJ314896-1|CAC85745.1| 163|Homo sapiens obscurin protein. 74 3e-12
AY358115-1|AAQ88482.1| 593|Homo sapiens DAAT9248 protein. 74 4e-12
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 74 4e-12
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 74 4e-12
AL589765-16|CAI17178.1| 593|Homo sapiens leucine rich repeat ne... 74 4e-12
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 74 4e-12
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 74 4e-12
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 74 4e-12
AF089868-1|AAD17799.1| 646|Homo sapiens cell surface glycoprote... 73 5e-12
M59262-1|AAA62835.1| 702|Homo sapiens carcinoembryonic antigen ... 73 6e-12
BC105999-1|AAI06000.1| 404|Homo sapiens CADM2 protein protein. 73 6e-12
U41901-1|AAC50569.1| 338|Homo sapiens LAMP protein. 73 8e-12
BC033803-1|AAH33803.1| 338|Homo sapiens limbic system-associate... 73 8e-12
BC141884-1|AAI41885.1| 1688|Homo sapiens SIGLEC1 protein protein. 72 1e-11
AK122586-1|BAC56927.1| 437|Homo sapiens FLJ00411 protein protein. 72 1e-11
AK074083-1|BAB84909.1| 1471|Homo sapiens FLJ00154 protein protein. 71 2e-11
M63888-1|AAA35959.1| 662|Homo sapiens heparin-binding growth fa... 71 3e-11
M63887-1|AAA35958.1| 822|Homo sapiens heparin-binding growth fa... 71 3e-11
BC113963-1|AAI13964.1| 262|Homo sapiens CADM4 protein protein. 71 3e-11
X54133-1|CAA38068.1| 1523|Homo sapiens protein-tyrosine phosphat... 70 4e-11
AL109804-4|CAC17543.1| 1709|Homo sapiens sialic acid binding Ig-... 70 6e-11
AK024462-1|BAB15752.1| 977|Homo sapiens FLJ00055 protein protein. 70 6e-11
AF230073-1|AAK00757.1| 1709|Homo sapiens sialoadhesin protein. 70 6e-11
AB209478-1|BAD92715.1| 1552|Homo sapiens protein tyrosine phosph... 70 6e-11
EF064734-1|ABK41917.1| 429|Homo sapiens Fc receptor-like 1 prot... 69 8e-11
BC033690-1|AAH33690.1| 429|Homo sapiens Fc receptor-like 1 prot... 69 8e-11
AY043464-1|AAK91777.1| 429|Homo sapiens Fc receptor-like protei... 69 8e-11
AL356276-3|CAH73054.1| 429|Homo sapiens Fc receptor-like 1 prot... 69 8e-11
AL356276-2|CAH73053.1| 428|Homo sapiens Fc receptor-like 1 prot... 69 8e-11
AL356276-1|CAH73052.1| 366|Homo sapiens Fc receptor-like 1 prot... 69 8e-11
AL163281-2|CAB90444.1| 1029|Homo sapiens human CHD2-52 down synd... 69 8e-11
AL139409-3|CAH70234.1| 429|Homo sapiens Fc receptor-like 1 prot... 69 8e-11
AL139409-2|CAH70233.1| 428|Homo sapiens Fc receptor-like 1 prot... 69 8e-11
AL139409-1|CAH70232.1| 366|Homo sapiens Fc receptor-like 1 prot... 69 8e-11
AK096690-1|BAC04842.1| 366|Homo sapiens protein ( Homo sapiens ... 69 8e-11
AF459634-1|AAL60250.1| 429|Homo sapiens immunoglobulin superfam... 69 8e-11
AF329488-1|AAL23898.1| 428|Homo sapiens IFGP1 protein. 69 8e-11
AJ277892-3|CAD12457.1| 5604|Homo sapiens Novex-3 Titin Isoform p... 69 1e-10
AC023270-1|AAX88844.1| 5604|Homo sapiens unknown protein. 69 1e-10
AK131073-1|BAC85123.1| 659|Homo sapiens FLJ00259 protein protein. 68 2e-10
AJ314905-1|CAC85752.1| 2212|Homo sapiens obscurin protein. 68 2e-10
AF109907-3|AAC97963.1| 1235|Homo sapiens hypothetical protein pr... 68 2e-10
AC005525-1|AAC32740.1| 381|Homo sapiens F22162_1 protein. 68 2e-10
AB046776-1|BAB13382.1| 1596|Homo sapiens KIAA1556 protein protein. 68 2e-10
BC045763-1|AAH45763.1| 1329|Homo sapiens SDK2 protein protein. 67 3e-10
BC043916-1|AAH43916.1| 767|Homo sapiens OBSCN protein protein. 67 3e-10
AY358330-1|AAQ88696.1| 477|Homo sapiens papilin protein. 67 3e-10
AL353593-1|CAI19283.1| 709|Homo sapiens obscurin, cytoskeletal ... 67 3e-10
AJ314903-1|CAC85750.1| 542|Homo sapiens obscurin protein. 67 3e-10
AB046848-1|BAB13454.1| 980|Homo sapiens KIAA1628 protein protein. 67 3e-10
AJ001054-1|CAA04504.1| 148|Homo sapiens NrCAM protein protein. 67 4e-10
BC024300-1|AAH24300.1| 605|Homo sapiens FSTL4 protein protein. 66 5e-10
AB014557-1|BAA31632.2| 1237|Homo sapiens KIAA0657 protein protein. 66 5e-10
BX537361-1|CAD97607.1| 1191|Homo sapiens hypothetical protein pr... 66 7e-10
BC128390-1|AAI28391.1| 1682|Homo sapiens ADAMTSL3 protein protein. 66 7e-10
BC128389-1|AAI28390.1| 1691|Homo sapiens ADAMTS-like 3 protein. 66 7e-10
BC036769-1|AAH36769.1| 504|Homo sapiens fibroblast growth facto... 66 7e-10
AY358303-1|AAQ88670.1| 504|Homo sapiens FGFRL1 protein. 66 7e-10
AL391822-1|CAI14656.1| 302|Homo sapiens neurofascin homolog (ch... 66 7e-10
AK172829-1|BAD18794.1| 440|Homo sapiens protein ( Homo sapiens ... 66 7e-10
AF190637-1|AAG17141.1| 1241|Homo sapiens nephrin protein. 66 7e-10
AF035835-1|AAC39687.1| 1241|Homo sapiens nephrin protein. 66 7e-10
AB033059-1|BAA86547.1| 1023|Homo sapiens KIAA1233 protein protein. 66 7e-10
AB028984-1|BAA83013.1| 693|Homo sapiens KIAA1061 protein protein. 66 7e-10
AJ277892-5|CAD12459.1| 2154|Homo sapiens Titin Novex-1 Isoform p... 66 1e-09
EF064732-1|ABK41915.1| 734|Homo sapiens Fc receptor-like 3 prot... 65 1e-09
BC028933-1|AAH28933.1| 742|Homo sapiens FCRL3 protein protein. 65 1e-09
AY043466-1|AAK91779.1| 734|Homo sapiens Fc receptor-like protei... 65 1e-09
AL356276-6|CAH73058.1| 734|Homo sapiens Fc receptor-like 3 prot... 65 1e-09
AL356276-5|CAH73056.1| 742|Homo sapiens Fc receptor-like 3 prot... 65 1e-09
AL356276-4|CAH73055.1| 707|Homo sapiens Fc receptor-like 3 prot... 65 1e-09
AF459027-1|AAL59390.1| 734|Homo sapiens immunoglobulin superfam... 65 1e-09
AF416901-1|AAL13290.1| 734|Homo sapiens SH2 domain-containing p... 65 1e-09
BC115397-1|AAI15398.1| 867|Homo sapiens IGSF22 protein protein. 64 2e-09
AK126303-1|BAC86520.1| 527|Homo sapiens protein ( Homo sapiens ... 64 3e-09
EF064730-1|ABK41913.1| 977|Homo sapiens Fc receptor-like 5 prot... 64 4e-09
BC101069-1|AAI01070.1| 977|Homo sapiens Fc receptor-like 5 prot... 64 4e-09
>DQ533874-1|ABF83431.1| 1378|Homo sapiens ROBO2 isoform b protein.
Length = 1378
Score = 508 bits (1253), Expect = e-143
Identities = 300/827 (36%), Positives = 434/827 (52%), Gaps = 45/827 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
P I+E P DV V++ +P TLNC+A G P+P I WYK G V +D +HR +LP+G L
Sbjct: 31 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 90
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
FFLR HGR D G Y C A N G A SRNA+L VA+LR++FR P A G+
Sbjct: 91 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPA 150
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
+LEC PPRG PEP +YWKK+ + + D + R+ + GG L+I + R++DAG Y C+ N
Sbjct: 151 ILECQPPRGHPEPTIYWKKD-KVRIDDKEERIS-IRGGKLMISNTRKSDAGMYTCVGTNM 208
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G R+S A L + +P + P + V +V F+C+V GDP P V W++ ++P
Sbjct: 209 VGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKD--DADLP 266
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
GR + DD +LR+ + DEG Y C AEN VG + AS LTV PP + P V
Sbjct: 267 RGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVA 326
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G F C G P+P +FW EG++ ++FP + +V LTI + ++D
Sbjct: 327 QGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSV-SPTGDLTITNIQRSD 385
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
+ +C A+ AGS + +L VT DRPPPII GP+NQTL + A+ C A
Sbjct: 386 A-GYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGD 444
Query: 425 PEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I+W EG ++ R + GTL +K+L SD+GTYTCVA+S G+ WS L
Sbjct: 445 PLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLD 504
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
V + D+S LPGPP+KP +VT SVTLSW Q G+ Y +E F
Sbjct: 505 V---TESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIEAF 560
Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
S+ S W +A V T Y V+ L P Y+F+VR N GLS PSP+SD
Sbjct: 561 SQSV---------SNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSD 611
Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-LNFYYLE 662
V D S GV + + L D +V L + T+++ W + +++
Sbjct: 612 PVRTQDISP---PAQGVDHRQVQKE--LGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQ 666
Query: 663 GLFIYFRPLDNI--TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
G + +R + T ++ + S + +L+K YE + P++ +F+G S
Sbjct: 667 GYRVMYRQTSGLQATSSWQNLDAKVPTERSAV-LVNLKKGVTYEIKVRPYFNEFQGMDSE 725
Query: 721 SRVAQTLDDVPDGPPINIEMFIL---NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
S+ +T ++ P PP ++ + + N+T++ + W PP QNGII Y + W
Sbjct: 726 SKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI---W--CL 780
Query: 778 ANKSMVAINTTVHQA-TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
N++ IN TV A S+I+ L G+ Y V++AA T G+G S+
Sbjct: 781 GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSE 827
Score = 120 bits (288), Expect = 4e-26
Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 19/295 (6%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T E P + +P++ V + C+ G P P +RW K +D R
Sbjct: 219 LTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD----ADLPRGRYDIKD 274
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+ LR + +D G Y C A N G + +ATL V +F + P + AQG TV
Sbjct: 275 DYTLRIKK-TMSTDEGTYMCIAENRVGKMEA-SATLTVRA-PPQFVVRPRDQIVAQGRTV 331
Query: 126 VLECLPPRGSPEPNVYWKKNG-QTLLFDG-----DSRMHLVDGGNLVIQDARQTDAGRYQ 179
C +G+P+P V+W+K G Q LLF +SR + G+L I + +++DAG Y
Sbjct: 332 TFPC-ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYI 390
Query: 180 CIARNAAGT-----RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
C A AG+ + L P ++ GP + + +C+ GDPLP +
Sbjct: 391 CQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVIS 450
Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
W + R + + G+L++ N+ ++D G Y+C A +S G S S L V
Sbjct: 451 WLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 505
Score = 61.7 bits (143), Expect = 2e-08
Identities = 49/190 (25%), Positives = 76/190 (40%), Gaps = 14/190 (7%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I P+ V V G C A GRP PT+ W +G R + + H +
Sbjct: 30 PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGER--VETDKDDPRSHRMLLPS 87
Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406
G + ++ + VC A NY G + R ++ + DD R P++
Sbjct: 88 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFR------QNPTD 141
Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ A+ C PEP I W + + R G L++ + KSD+G Y
Sbjct: 142 VVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMY 201
Query: 466 TCVASSRHGK 475
TCV ++ G+
Sbjct: 202 TCVGTNMVGE 211
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D +T P I++ P + T+A A L C+A G P P I W K G R+ +
Sbjct: 410 DVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE 469
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
G L+ + R+ SD G Y C AT+S G S +A L V
Sbjct: 470 QGT--LQIKNLRI-SDTGTYTCVATSSSGET-SWSAVLDV 505
>DQ533873-1|ABF83430.1| 1394|Homo sapiens ROBO2 isoform a protein.
Length = 1394
Score = 508 bits (1253), Expect = e-143
Identities = 300/827 (36%), Positives = 434/827 (52%), Gaps = 45/827 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
P I+E P DV V++ +P TLNC+A G P+P I WYK G V +D +HR +LP+G L
Sbjct: 47 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 106
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
FFLR HGR D G Y C A N G A SRNA+L VA+LR++FR P A G+
Sbjct: 107 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPA 166
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
+LEC PPRG PEP +YWKK+ + + D + R+ + GG L+I + R++DAG Y C+ N
Sbjct: 167 ILECQPPRGHPEPTIYWKKD-KVRIDDKEERIS-IRGGKLMISNTRKSDAGMYTCVGTNM 224
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G R+S A L + +P + P + V +V F+C+V GDP P V W++ ++P
Sbjct: 225 VGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKD--DADLP 282
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
GR + DD +LR+ + DEG Y C AEN VG + AS LTV PP + P V
Sbjct: 283 RGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVA 342
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G F C G P+P +FW EG++ ++FP + +V LTI + ++D
Sbjct: 343 QGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSV-SPTGDLTITNIQRSD 401
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
+ +C A+ AGS + +L VT DRPPPII GP+NQTL + A+ C A
Sbjct: 402 A-GYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGD 460
Query: 425 PEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I+W EG ++ R + GTL +K+L SD+GTYTCVA+S G+ WS L
Sbjct: 461 PLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLD 520
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
V + D+S LPGPP+KP +VT SVTLSW Q G+ Y +E F
Sbjct: 521 V---TESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIEAF 576
Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
S+ S W +A V T Y V+ L P Y+F+VR N GLS PSP+SD
Sbjct: 577 SQSV---------SNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSD 627
Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-LNFYYLE 662
V D S GV + + L D +V L + T+++ W + +++
Sbjct: 628 PVRTQDISP---PAQGVDHRQVQKE--LGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQ 682
Query: 663 GLFIYFRPLDNI--TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
G + +R + T ++ + S + +L+K YE + P++ +F+G S
Sbjct: 683 GYRVMYRQTSGLQATSSWQNLDAKVPTERSAV-LVNLKKGVTYEIKVRPYFNEFQGMDSE 741
Query: 721 SRVAQTLDDVPDGPPINIEMFIL---NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
S+ +T ++ P PP ++ + + N+T++ + W PP QNGII Y + W
Sbjct: 742 SKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI---W--CL 796
Query: 778 ANKSMVAINTTVHQA-TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
N++ IN TV A S+I+ L G+ Y V++AA T G+G S+
Sbjct: 797 GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSE 843
Score = 120 bits (288), Expect = 4e-26
Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 19/295 (6%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T E P + +P++ V + C+ G P P +RW K +D R
Sbjct: 235 LTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD----ADLPRGRYDIKD 290
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+ LR + +D G Y C A N G + +ATL V +F + P + AQG TV
Sbjct: 291 DYTLRIKK-TMSTDEGTYMCIAENRVGKMEA-SATLTVRA-PPQFVVRPRDQIVAQGRTV 347
Query: 126 VLECLPPRGSPEPNVYWKKNG-QTLLFDG-----DSRMHLVDGGNLVIQDARQTDAGRYQ 179
C +G+P+P V+W+K G Q LLF +SR + G+L I + +++DAG Y
Sbjct: 348 TFPC-ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYI 406
Query: 180 CIARNAAGT-----RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
C A AG+ + L P ++ GP + + +C+ GDPLP +
Sbjct: 407 CQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVIS 466
Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
W + R + + G+L++ N+ ++D G Y+C A +S G S S L V
Sbjct: 467 WLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 521
Score = 61.7 bits (143), Expect = 2e-08
Identities = 49/190 (25%), Positives = 76/190 (40%), Gaps = 14/190 (7%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I P+ V V G C A GRP PT+ W +G R + + H +
Sbjct: 46 PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGER--VETDKDDPRSHRMLLPS 103
Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406
G + ++ + VC A NY G + R ++ + DD R P++
Sbjct: 104 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFR------QNPTD 157
Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ A+ C PEP I W + + R G L++ + KSD+G Y
Sbjct: 158 VVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMY 217
Query: 466 TCVASSRHGK 475
TCV ++ G+
Sbjct: 218 TCVGTNMVGE 227
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D +T P I++ P + T+A A L C+A G P P I W K G R+ +
Sbjct: 426 DVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE 485
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
G L+ + R+ SD G Y C AT+S G S +A L V
Sbjct: 486 QGT--LQIKNLRI-SDTGTYTCVATSSSGET-SWSAVLDV 521
>AB046788-1|BAB13394.1| 1380|Homo sapiens KIAA1568 protein protein.
Length = 1380
Score = 508 bits (1253), Expect = e-143
Identities = 300/827 (36%), Positives = 434/827 (52%), Gaps = 45/827 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
P I+E P DV V++ +P TLNC+A G P+P I WYK G V +D +HR +LP+G L
Sbjct: 33 PRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSGSL 92
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
FFLR HGR D G Y C A N G A SRNA+L VA+LR++FR P A G+
Sbjct: 93 FFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVVAAGEPA 152
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
+LEC PPRG PEP +YWKK+ + + D + R+ + GG L+I + R++DAG Y C+ N
Sbjct: 153 ILECQPPRGHPEPTIYWKKD-KVRIDDKEERIS-IRGGKLMISNTRKSDAGMYTCVGTNM 210
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G R+S A L + +P + P + V +V F+C+V GDP P V W++ ++P
Sbjct: 211 VGERDSDPAELTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKD--DADLP 268
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
GR + DD +LR+ + DEG Y C AEN VG + AS LTV PP + P V
Sbjct: 269 RGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVVRPRDQIVA 328
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G F C G P+P +FW EG++ ++FP + +V LTI + ++D
Sbjct: 329 QGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSV-SPTGDLTITNIQRSD 387
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
+ +C A+ AGS + +L VT DRPPPII GP+NQTL + A+ C A
Sbjct: 388 A-GYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGD 446
Query: 425 PEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I+W EG ++ R + GTL +K+L SD+GTYTCVA+S G+ WS L
Sbjct: 447 PLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLD 506
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
V + D+S LPGPP+KP +VT SVTLSW Q G+ Y +E F
Sbjct: 507 V---TESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIEAF 562
Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
S+ S W +A V T Y V+ L P Y+F+VR N GLS PSP+SD
Sbjct: 563 SQSV---------SNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSD 613
Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-LNFYYLE 662
V D S GV + + L D +V L + T+++ W + +++
Sbjct: 614 PVRTQDISP---PAQGVDHRQVQKE--LGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQ 668
Query: 663 GLFIYFRPLDNI--TIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
G + +R + T ++ + S + +L+K YE + P++ +F+G S
Sbjct: 669 GYRVMYRQTSGLQATSSWQNLDAKVPTERSAV-LVNLKKGVTYEIKVRPYFNEFQGMDSE 727
Query: 721 SRVAQTLDDVPDGPPINIEMFIL---NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
S+ +T ++ P PP ++ + + N+T++ + W PP QNGII Y + W
Sbjct: 728 SKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI---W--CL 782
Query: 778 ANKSMVAINTTVHQA-TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
N++ IN TV A S+I+ L G+ Y V++AA T G+G S+
Sbjct: 783 GNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVGVKSE 829
Score = 120 bits (288), Expect = 4e-26
Identities = 85/295 (28%), Positives = 134/295 (45%), Gaps = 19/295 (6%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T E P + +P++ V + C+ G P P +RW K +D R
Sbjct: 221 LTVFERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDD----ADLPRGRYDIKD 276
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+ LR + +D G Y C A N G + +ATL V +F + P + AQG TV
Sbjct: 277 DYTLRIKK-TMSTDEGTYMCIAENRVGKMEA-SATLTVRA-PPQFVVRPRDQIVAQGRTV 333
Query: 126 VLECLPPRGSPEPNVYWKKNG-QTLLFDG-----DSRMHLVDGGNLVIQDARQTDAGRYQ 179
C +G+P+P V+W+K G Q LLF +SR + G+L I + +++DAG Y
Sbjct: 334 TFPC-ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYI 392
Query: 180 CIARNAAGT-----RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
C A AG+ + L P ++ GP + + +C+ GDPLP +
Sbjct: 393 CQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVIS 452
Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
W + R + + G+L++ N+ ++D G Y+C A +S G S S L V
Sbjct: 453 WLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV 507
Score = 61.7 bits (143), Expect = 2e-08
Identities = 49/190 (25%), Positives = 76/190 (40%), Gaps = 14/190 (7%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I P+ V V G C A GRP PT+ W +G R + + H +
Sbjct: 32 PPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGER--VETDKDDPRSHRMLLPS 89
Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406
G + ++ + VC A NY G + R ++ + DD R P++
Sbjct: 90 GSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFR------QNPTD 143
Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ A+ C PEP I W + + R G L++ + KSD+G Y
Sbjct: 144 VVVAAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGMY 203
Query: 466 TCVASSRHGK 475
TCV ++ G+
Sbjct: 204 TCVGTNMVGE 213
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D +T P I++ P + T+A A L C+A G P P I W K G R+ +
Sbjct: 412 DVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE 471
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
G L+ + R+ SD G Y C AT+S G S +A L V
Sbjct: 472 QGT--LQIKNLRI-SDTGTYTCVATSSSGET-SWSAVLDV 507
>AF040990-1|AAC39575.1| 1651|Homo sapiens roundabout 1 protein.
Length = 1651
Score = 500 bits (1232), Expect = e-140
Identities = 308/893 (34%), Positives = 458/893 (51%), Gaps = 64/893 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
P I+E P D+ V++ +PATLNC+A G P+P I WYKGG V +D +HR +LP+G L
Sbjct: 68 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 127
Query: 67 FFLRATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
FFLR HGR D GVY C A N G A S NA+L VA+LR++FR P A G+
Sbjct: 128 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 187
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
V+EC PPRG PEP + WKK+G L D D R+ + GG L+I R++DAG+Y C+ N
Sbjct: 188 VMECQPPRGHPEPTISWKKDGSPL-DDKDERI-TIRGGKLMITYTRKSDAGKYVCVGTNM 245
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G RES +A L + +P + P ++ S F+C GDP+P V WR+ G +P
Sbjct: 246 VGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD--DGELP 303
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
R ++ DD +L++ V D G Y+C AEN VG AS LTV +PP + P V
Sbjct: 304 KSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKPRDQVVA 363
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PGMSRDKYHATAVFDGVTVLTINDTD 362
G F C ATG P+P +FW EG++ ++F P S ++ + D LTI +
Sbjct: 364 LGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQ 419
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
++D +C +N AGS + L VT DRPPP+I GP NQT+ + V C A
Sbjct: 420 RSDV-GYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVA 478
Query: 422 ICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
+P P I W +G + Q+ R +G L ++ D+G YTC+AS+ G+ WS
Sbjct: 479 TGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSA 538
Query: 481 ALLVDS---PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILG 537
+ V P+ P R D + +P P+KP +V+ +VTLSW N G++
Sbjct: 539 YIEVQEFGVPVQPP----RPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TS 593
Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
Y +E FS SG++ W +A V +K L P Y+F+VR N++G+S
Sbjct: 594 YIIEAFSH--ASGSS-------WQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISD 644
Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-L 656
PS +SD V D L GV + R L + ++ L T + S +I++ W +
Sbjct: 645 PSQISDPVKTQD---VLPTSQGVDHKQVQRE--LGNAVLHLHNPTVLSSSSIEVHWTVDQ 699
Query: 657 NFYYLEGLFIYFRPL-----DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFY 711
Y++G I +RP ++ + +E++T ++ V I LRK YE PF+
Sbjct: 700 QSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVV----IPDLRKGVNYEIKARPFF 755
Query: 712 KKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITGYNV 769
+F+G S + A+TL++ P PP + + N T + + W PP QNG++ Y V
Sbjct: 756 NEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKV 815
Query: 770 VVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFN 828
W N++ IN TV +T S+++ L G+ YSV++AA T G G S+ +
Sbjct: 816 ---W--CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQ 870
Query: 829 IDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIY 881
+D+ + + + ++S D V + F IGA ++V + +Y
Sbjct: 871 LDAHGNPVSPEDQVSLAQQIS----DVVKQPAFIAGIGAACWIILMVFSIWLY 919
Score = 115 bits (277), Expect = 9e-25
Identities = 98/333 (29%), Positives = 148/333 (44%), Gaps = 31/333 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
E P +++P ++ V A C A G P P +RW K G L S I L
Sbjct: 260 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS--RYEIRDDHTLKI 317
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
+ T G D G Y C A N G A + +ATL V F ++P + A G TV +
Sbjct: 318 RKVTAG----DMGSYTCVAENMVGKAEA-SATLTVQE-PPHFVVKPRDQVVALGRTVTFQ 371
Query: 129 CLPPRGSPEPNVYWKKNG-QTLLF-----DGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
C G+P+P ++W++ G Q LLF SR + G+L I + +++D G Y C
Sbjct: 372 C-EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQT 430
Query: 183 RNAAG---TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
N AG T+ T I + P + GP + + C G P+P +LWR+
Sbjct: 431 LNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRK 490
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291
+ R+K L++G L++ L D G Y+C A G + S Y+ V +
Sbjct: 491 DGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQ 550
Query: 292 ---PPSINLSPNSVN-VESGNVARFTCTATGRP 320
P NL P++ + E +V+R T T + +P
Sbjct: 551 PPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQP 583
Score = 79.4 bits (187), Expect = 7e-14
Identities = 62/195 (31%), Positives = 91/195 (46%), Gaps = 20/195 (10%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--------SDTH 57
+T E P+ + +P D VA + T C A G+P PAI W + G + S +
Sbjct: 345 LTVQEPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSR 404
Query: 58 RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREE----FRL 112
S+ G L SD G Y C+ N G+ ++ A L V V+ + R
Sbjct: 405 FSVSQTGDLTITNVQ----RSDVGYYICQTLNVAGSIITK-AYLEVTDVIADRPPPVIRQ 459
Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
P ++ A T VL C+ GSP P + W+K+G L+ DSR+ ++ G L I+ A+
Sbjct: 460 GPVNQTVAVDGTFVLSCV-ATGSPVPTILWRKDG-VLVSTQDSRIKQLENGVLQIRYAKL 517
Query: 173 TDAGRYQCIARNAAG 187
D GRY CIA +G
Sbjct: 518 GDTGRYTCIASTPSG 532
Score = 64.5 bits (150), Expect = 2e-09
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 14/190 (7%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I P+ + V G A C A GRP PT+ W G R + + H +
Sbjct: 67 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGER--VETDKDDPRSHRMLLPS 124
Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406
G + ++ VC A NY G + ++ + DD R PS+
Sbjct: 125 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFR------QNPSD 178
Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ + AV C PEP I+W +G L R G L++ KSD+G Y
Sbjct: 179 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKY 238
Query: 466 TCVASSRHGK 475
CV ++ G+
Sbjct: 239 VCVGTNMVGE 248
Score = 46.0 bits (104), Expect = 8e-04
Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + P I + P++ TVA L+C A GSP P I W K GVLV + R
Sbjct: 447 DVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 506
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94
G+ +R + ++ D G Y C A+ G A
Sbjct: 507 NGVLQIR--YAKL-GDTGRYTCIASTPSGEA 534
>BC112336-1|AAI12337.1| 1607|Homo sapiens ROBO1 protein protein.
Length = 1607
Score = 494 bits (1219), Expect = e-139
Identities = 320/977 (32%), Positives = 486/977 (49%), Gaps = 71/977 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
P I+E P D+ V++ +PATLNC+A G P+P I WYKGG V +D +HR +LP+G L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 67 FFLRATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
FFLR HGR D GVY C A N G A S NA+L VA+LR++FR P A G+
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 148
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
V+EC PPRG PEP + WKK+G L D D R+ + GG L+I R++DAG+Y C+ N
Sbjct: 149 VMECQPPRGHPEPTISWKKDGSP-LDDKDERI-TIRGGKLMITYTRKSDAGKYVCVGTNM 206
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G RES +A L + +P + P ++ S F+C GDP+P V WR+ G +P
Sbjct: 207 VGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD--DGELP 264
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSV 302
R ++ DD +L++ V D G Y+C AEN VG AS LTV +PP + P
Sbjct: 265 KSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQ 324
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PGMSRDKYHATAVFDGVTVLTIN 359
V G F C ATG P+P +FW EG++ ++F P S ++ + D LTI
Sbjct: 325 VVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTIT 380
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ ++D +C +N AGS + L VT DRPPP+I GP NQT+ + V
Sbjct: 381 NVQRSDV-GYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLS 439
Query: 419 CTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
C A +P P I W +G + Q+ R +G L ++ D+G YTC+AS+ G+
Sbjct: 440 CVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 499
Query: 478 WSGALLVDS---PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
WS + V P+ P R D + +P P+KP +V+ +VTLSW N G++
Sbjct: 500 WSAYIEVQEFGVPVQPP----RPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP 555
Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
Y +E FS SG++ W +A V +K L P Y+F+VR N++G
Sbjct: 556 -TSYIIEAFSH--ASGSS-------WQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYG 605
Query: 595 LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
+S PS +SD V D L GV + R L + ++ L T + S +I++ W
Sbjct: 606 ISDPSQISDPVKTQD---VLPTSQGVDHKQVQRE--LGNAVLHLHNPTVLSSSSIEVHWT 660
Query: 655 I-LNFYYLEGLFIYFRPL-----DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLI 708
+ Y++G I +RP ++ + +E++T ++ V I LRK YE
Sbjct: 661 VDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVV----IPDLRKGVNYEIKAR 716
Query: 709 PFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITG 766
PF+ +F+G S + A+TL++ P PP + + N T + + W PP QNG++
Sbjct: 717 PFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQE 776
Query: 767 YNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
Y V W N++ IN TV +T S+++ L G+ YSV++AA T G G S+
Sbjct: 777 YKV---W--CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQ 831
Query: 826 YFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIY---V 882
+ +D+ + + + ++S D V + F IGA ++V + +Y
Sbjct: 832 FIQLDAHGNPVSPEDQVSLAQQIS----DVVKQPAFIAGIGAACWIILMVFSIWLYRHRK 887
Query: 883 RKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQ 942
++ + + + + + G V+ +++S P + +T T + +
Sbjct: 888 KRNGLTSTYAGIRKVTYQRGGEAVSSGGRPGLLNISEPAAQPWLADTWPNTGN-NHNDCS 946
Query: 943 PGVCLSGNQTSQSKEKT 959
C +GN S S T
Sbjct: 947 ISCCTAGNGNSDSNLTT 963
Score = 118 bits (284), Expect = 1e-25
Identities = 100/335 (29%), Positives = 150/335 (44%), Gaps = 32/335 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
E P +++P ++ V A C A G P P +RW K G L S I L
Sbjct: 221 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS--RYEIRDDHTLKI 278
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVV 126
+ T G D G Y C A N G A + +ATL V V E F ++P + A G TV
Sbjct: 279 RKVTAG----DMGSYTCVAENMVGKAEA-SATLTVQVGSEPPHFVVKPRDQVVALGRTVT 333
Query: 127 LECLPPRGSPEPNVYWKKNG-QTLLF-----DGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+C G+P+P ++W++ G Q LLF SR + G+L I + +++D G Y C
Sbjct: 334 FQC-EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYIC 392
Query: 181 IARNAAG---TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
N AG T+ T I + P + GP + + C G P+P +LW
Sbjct: 393 QTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILW 452
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---- 291
R+ + R+K L++G L++ L D G Y+C A G + S Y+ V +
Sbjct: 453 RKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 512
Query: 292 -----PPSINLSPNSVN-VESGNVARFTCTATGRP 320
P NL P++ + E +V+R T T + +P
Sbjct: 513 VQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQP 547
Score = 64.5 bits (150), Expect = 2e-09
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 14/190 (7%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I P+ + V G A C A GRP PT+ W G R + + H +
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGER--VETDKDDPRSHRMLLPS 85
Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406
G + ++ VC A NY G + ++ + DD R PS+
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFR------QNPSD 139
Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ + AV C PEP I+W +G L R G L++ KSD+G Y
Sbjct: 140 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKY 199
Query: 466 TCVASSRHGK 475
CV ++ G+
Sbjct: 200 VCVGTNMVGE 209
Score = 46.0 bits (104), Expect = 8e-04
Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + P I + P++ TVA L+C A GSP P I W K GVLV + R
Sbjct: 411 DVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 470
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94
G+ +R + ++ D G Y C A+ G A
Sbjct: 471 NGVLQIR--YAKL-GDTGRYTCIASTPSGEA 498
>BC115022-1|AAI15023.1| 1551|Homo sapiens ROBO1 protein protein.
Length = 1551
Score = 493 bits (1215), Expect = e-138
Identities = 319/977 (32%), Positives = 485/977 (49%), Gaps = 71/977 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
P I+E P D+ V++ +PATLNC+A G P+P I WYKGG V +D +HR +LP+G L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 67 FFLRATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
FFLR HGR D GVY C A N G A S NA+L VA+LR++FR P G+
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVVVGEPA 148
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
V+EC PPRG PEP + WKK+G L D D R+ + GG L+I R++DAG+Y C+ N
Sbjct: 149 VMECQPPRGHPEPTISWKKDGSP-LDDKDERI-TIRGGKLMITYTRKSDAGKYVCVGTNM 206
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G RES +A L + +P + P ++ S F+C GDP+P V WR+ G +P
Sbjct: 207 VGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD--DGELP 264
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSV 302
R ++ DD +L++ V D G Y+C AEN VG AS LTV +PP + P
Sbjct: 265 KSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQ 324
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PGMSRDKYHATAVFDGVTVLTIN 359
V G F C ATG P+P +FW EG++ ++F P S ++ + D LTI
Sbjct: 325 VVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTIT 380
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ ++D +C +N AGS + L VT DRPPP+I GP NQT+ + V
Sbjct: 381 NVQRSDV-GYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLS 439
Query: 419 CTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
C A +P P I W +G + Q+ R +G L ++ D+G YTC+AS+ G+
Sbjct: 440 CVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 499
Query: 478 WSGALLVDS---PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
WS + V P+ P R D + +P P+KP +V+ +VTLSW N G++
Sbjct: 500 WSAYIEVQEFGVPVQPP----RPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP 555
Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
Y +E FS SG++ W +A V +K L P Y+F+VR N++G
Sbjct: 556 -TSYIIEAFSH--ASGSS-------WQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYG 605
Query: 595 LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
+S PS +SD V D L GV + R L + ++ L T + S +I++ W
Sbjct: 606 ISDPSQISDPVKTQD---VLPTSQGVDHKQVQRE--LGNAVLHLHNPTVLSSSSIEVHWT 660
Query: 655 I-LNFYYLEGLFIYFRPL-----DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLI 708
+ Y++G I +RP ++ + +E++T ++ V I LRK YE
Sbjct: 661 VDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVV----IPDLRKGVNYEIKAR 716
Query: 709 PFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITG 766
PF+ +F+G S + A+TL++ P PP + + N T + + W PP QNG++
Sbjct: 717 PFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQE 776
Query: 767 YNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
Y V W N++ IN TV +T S+++ L G+ YSV++AA T G G S+
Sbjct: 777 YKV---W--CLGNETRYHINKTVDGSTLSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQ 831
Query: 826 YFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIY---V 882
+ +D+ + + + ++S D V + F IGA ++V + +Y
Sbjct: 832 FIQLDAHGNPVSPEDQVSLAQQIS----DVVKQPAFIAGIGAACWIILMVFSIWLYRHRK 887
Query: 883 RKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQ 942
++ + + + + + G V+ +++S P + +T T + +
Sbjct: 888 KRNGLTSTYAGIRKVTYQRGGEAVSSGGRPGLLNISEPAAQPWLADTWPNTGN-NHNDCS 946
Query: 943 PGVCLSGNQTSQSKEKT 959
C +GN S S T
Sbjct: 947 ISCCTAGNGNSDSNLTT 963
Score = 118 bits (284), Expect = 1e-25
Identities = 100/335 (29%), Positives = 150/335 (44%), Gaps = 32/335 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
E P +++P ++ V A C A G P P +RW K G L S I L
Sbjct: 221 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS--RYEIRDDHTLKI 278
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVV 126
+ T G D G Y C A N G A + +ATL V V E F ++P + A G TV
Sbjct: 279 RKVTAG----DMGSYTCVAENMVGKAEA-SATLTVQVGSEPPHFVVKPRDQVVALGRTVT 333
Query: 127 LECLPPRGSPEPNVYWKKNG-QTLLF-----DGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+C G+P+P ++W++ G Q LLF SR + G+L I + +++D G Y C
Sbjct: 334 FQC-EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYIC 392
Query: 181 IARNAAG---TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
N AG T+ T I + P + GP + + C G P+P +LW
Sbjct: 393 QTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILW 452
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---- 291
R+ + R+K L++G L++ L D G Y+C A G + S Y+ V +
Sbjct: 453 RKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 512
Query: 292 -----PPSINLSPNSVN-VESGNVARFTCTATGRP 320
P NL P++ + E +V+R T T + +P
Sbjct: 513 VQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQP 547
Score = 64.1 bits (149), Expect = 3e-09
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 14/190 (7%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I P+ + V G A C A GRP PT+ W G R + + H +
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGER--VETDKDDPRSHRMLLPS 85
Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406
G + ++ VC A NY G + ++ + DD R PS+
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFR------QNPSD 139
Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ + AV C PEP I+W +G L R G L++ KSD+G Y
Sbjct: 140 VMVVVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKY 199
Query: 466 TCVASSRHGK 475
CV ++ G+
Sbjct: 200 VCVGTNMVGE 209
Score = 46.0 bits (104), Expect = 8e-04
Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + P I + P++ TVA L+C A GSP P I W K GVLV + R
Sbjct: 411 DVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 470
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94
G+ +R + ++ D G Y C A+ G A
Sbjct: 471 NGVLQIR--YAKL-GDTGRYTCIASTPSGEA 498
>BC115020-1|AAI15021.1| 1606|Homo sapiens ROBO1 protein protein.
Length = 1606
Score = 492 bits (1214), Expect = e-138
Identities = 319/977 (32%), Positives = 485/977 (49%), Gaps = 71/977 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-----THRSILPAGGL 66
P I+E P D+ V++ +PATLNC+A G P+P I WYKGG V +D +HR +LP+G L
Sbjct: 29 PRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSL 88
Query: 67 FFLRATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
FFLR HGR D GVY C A N G A S NA+L VA+LR++FR P A G+
Sbjct: 89 FFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGEPA 148
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
V+EC PPRG PEP + WKK+G L D D R+ + GG L+I R++DAG+Y C+ N
Sbjct: 149 VMECQPPRGHPEPTISWKKDGSP-LDDKDERI-TIRGGKLMITYTRKSDAGKYVCVGTNM 206
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G RES +A L + +P + P ++ S F+C GDP+P V WR+ G +P
Sbjct: 207 VGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKD--DGELP 264
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSV 302
R ++ DD +L++ V D G Y+C AEN VG AS LTV +PP + P
Sbjct: 265 KSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQVGSEPPHFVVKPRDQ 324
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PGMSRDKYHATAVFDGVTVLTIN 359
V G F C ATG P+P +FW EG++ ++F P S ++ + D LTI
Sbjct: 325 VVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTIT 380
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ ++D +C +N AGS + L VT DRPPP+I GP NQT+ + V
Sbjct: 381 NVQRSDV-GYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLS 439
Query: 419 CTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
C A +P P I W +G + Q+ R +G L ++ D+G YTC+AS+ G+
Sbjct: 440 CVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEAT 499
Query: 478 WSGALLVDS---PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
WS + V P+ P R D + +P P+KP +V+ +VTLSW N G++
Sbjct: 500 WSAYIEVQEFGVPVQPP----RPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP 555
Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
Y +E FS SG++ W +A V +K L P Y+F+VR N++G
Sbjct: 556 -TSYIIEAFSH--ASGSS-------WQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYG 605
Query: 595 LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
+S PS +SD V D L GV + R L + ++ L T + +I++ W
Sbjct: 606 ISDPSQISDPVKTQD---VLPTSQGVDHKQVQRE--LGNAVLHLHNPTVLSPSSIEVHWT 660
Query: 655 I-LNFYYLEGLFIYFRPL-----DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLI 708
+ Y++G I +RP ++ + +E++T ++ V I LRK YE
Sbjct: 661 VDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVV----IPDLRKGVNYEIKAR 716
Query: 709 PFYKKFEGKPSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITG 766
PF+ +F+G S + A+TL++ P PP + + N T + + W PP QNG++
Sbjct: 717 PFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQE 776
Query: 767 YNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
Y V W N++ IN TV +T S+++ L G+ YSV++AA T G G S+
Sbjct: 777 YKV---W--CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQ 831
Query: 826 YFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIY---V 882
+ +D+ + + + ++S D V + F IGA ++V + +Y
Sbjct: 832 FIQLDAHGNPVSPEDQVSLAQQIS----DVVKQPAFIAGIGAACWIILMVFSIWLYRHRK 887
Query: 883 RKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQ 942
++ + + + + + G V+ +++S P + +T T + +
Sbjct: 888 KRNGLTSTYAGIRKVTYQRGGEAVSSGGRPGLLNISEPAAQPWLADTWPNTGN-NHNDCS 946
Query: 943 PGVCLSGNQTSQSKEKT 959
C +GN S S T
Sbjct: 947 ISCCTAGNGNSDSNLTT 963
Score = 118 bits (284), Expect = 1e-25
Identities = 100/335 (29%), Positives = 150/335 (44%), Gaps = 32/335 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
E P +++P ++ V A C A G P P +RW K G L S I L
Sbjct: 221 ERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS--RYEIRDDHTLKI 278
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVV 126
+ T G D G Y C A N G A + +ATL V V E F ++P + A G TV
Sbjct: 279 RKVTAG----DMGSYTCVAENMVGKAEA-SATLTVQVGSEPPHFVVKPRDQVVALGRTVT 333
Query: 127 LECLPPRGSPEPNVYWKKNG-QTLLF-----DGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+C G+P+P ++W++ G Q LLF SR + G+L I + +++D G Y C
Sbjct: 334 FQC-EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYIC 392
Query: 181 IARNAAG---TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
N AG T+ T I + P + GP + + C G P+P +LW
Sbjct: 393 QTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILW 452
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---- 291
R+ + R+K L++G L++ L D G Y+C A G + S Y+ V +
Sbjct: 453 RKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVP 512
Query: 292 -----PPSINLSPNSVN-VESGNVARFTCTATGRP 320
P NL P++ + E +V+R T T + +P
Sbjct: 513 VQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQP 547
Score = 64.5 bits (150), Expect = 2e-09
Identities = 51/190 (26%), Positives = 75/190 (39%), Gaps = 14/190 (7%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I P+ + V G A C A GRP PT+ W G R + + H +
Sbjct: 28 PPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGER--VETDKDDPRSHRMLLPS 85
Query: 352 G--VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPIITNGPSN 406
G + ++ VC A NY G + ++ + DD R PS+
Sbjct: 86 GSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFR------QNPSD 139
Query: 407 QTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ + AV C PEP I+W +G L R G L++ KSD+G Y
Sbjct: 140 VMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKY 199
Query: 466 TCVASSRHGK 475
CV ++ G+
Sbjct: 200 VCVGTNMVGE 209
Score = 46.0 bits (104), Expect = 8e-04
Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + P I + P++ TVA L+C A GSP P I W K GVLV + R
Sbjct: 411 DVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 470
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94
G+ +R + ++ D G Y C A+ G A
Sbjct: 471 NGVLQIR--YAKL-GDTGRYTCIASTPSGEA 498
>AY509035-1|AAS91662.1| 1386|Homo sapiens roundabout-like protein 3
protein.
Length = 1386
Score = 436 bits (1073), Expect = e-121
Identities = 283/834 (33%), Positives = 414/834 (49%), Gaps = 45/834 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAGGL 66
P I+EQP D+ V+R +PATL CRA G P P I WYK G V + HR +LP+G L
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 67 FFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
FF R HGR D GVY C A N G A SRNA+L VAVLR++FR P + A G+
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPA 183
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
VLEC+PPRG PEP+V W+K+G L + + R+ + GG L++ ++DAG Y C+A N
Sbjct: 184 VLECVPPRGHPEPSVSWRKDGARLK-EEEGRI-TIRGGKLMMSHTLKSDAGMYVCVASNM 241
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
AG RESA A + + +P + P + V + VTF C V GDP P + WR+ G +P
Sbjct: 242 AGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKE--DGELP 299
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
GR ++ D SL + +V DEG Y+C AENSVG ASG L+V+ PP + P
Sbjct: 300 TGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAA 359
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G F C G P P +FW EG++ ++FP S +V L I + D
Sbjct: 360 PGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSV-SPRGQLNITAVQRGD 418
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
+ VC AV+ AGS + L + D PP+I GP+NQTL + S PC
Sbjct: 419 A-GYYVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGN 477
Query: 425 PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P+P + W +G+ L + + T +GTL + ++ + D G Y+CVA S G+ WSG L
Sbjct: 478 PQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLK 537
Query: 484 V--DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
+ D ++P+ + SS PG P++P+ +T S+TL+W N + G +++ Y +E
Sbjct: 538 MREDWGVSPD----PPTEPSSPPGAPSQPVVTEITKNSITLTWKPNPQTG-AAVTSYVIE 592
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
FS P W +A V + V L P Y+F+VR + GLS PSPV
Sbjct: 593 AFS---------PAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPV 643
Query: 602 SDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN-FYY 660
S+ V D S S V + + L + V L E + +T+++ W +
Sbjct: 644 SEPVRTQDSSPS----RPVEDPWRGQQG-LAEVAVRLQEPIVLGPRTLQVSWTVDGPVQL 698
Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
++G + +R + M L S + L T+ + + ++ G S
Sbjct: 699 VQGFRVSWRVAGPEGGSWTMLD-LQSPSQQSTVLRGLPPGTQIQIKVQAQGQEGLGAESL 757
Query: 721 SRVAQTLDDVPDGPPINIEMFI--LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778
S ++ P GPP + + + +++ + W PP QNG+IT Y + W
Sbjct: 758 SVTRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEYQI---W--CLG 812
Query: 779 NKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDS 831
N+S +N + A S ++ L G+ Y +AA T G+G S V + S
Sbjct: 813 NESRFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVLVQLPS 866
Score = 126 bits (303), Expect = 6e-28
Identities = 102/339 (30%), Positives = 157/339 (46%), Gaps = 40/339 (11%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P + +P++ V P T C G P P +RW K LP G + +
Sbjct: 256 ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRK---------EDGELPT-GRYEI 305
Query: 70 RATH----GRVHS-DAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGD 123
R+ H G V + D G Y C A NS G A S + ++HV + +P+ + +A G+
Sbjct: 306 RSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVP---PQLVTQPQDQMAAPGE 362
Query: 124 TVVLECLPPRGSPEPNVYWKKNG-QTLLFDGDS-----RMHLVDGGNLVIQDARQTDAGR 177
+V +C +G+P P ++W+K G Q LLF S R + G L I ++ DAG
Sbjct: 363 SVAFQC-ETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGY 421
Query: 178 YQCIARNAAGT-RESAIATLK----IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
Y C A + AG+ A+ +K + P ++ GP + GSSV CRV G+P P
Sbjct: 422 YVCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPS 481
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-- 290
V W++ + K + +G+L + NV D G YSC A++S G + SG+L +
Sbjct: 482 VRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMRED 541
Query: 291 -----DPPSINLSPNSVNVES--GNVARFTCTATGRPEP 322
DPP+ SP + + + + T T +P P
Sbjct: 542 WGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNP 580
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P I++ P + T+ L CR G+P P++RW K G + D + A G +
Sbjct: 448 GLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLY 507
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTA 94
+ D G Y C A +S G A
Sbjct: 508 IANVQ---EMDMGFYSCVAKSSTGEA 530
>AK056544-1|BAB71212.1| 1034|Homo sapiens protein ( Homo sapiens
cDNA FLJ31982 fis, clone NT2RP7008550, highly similar to
Mus musculus rig-1 protein mRNA. ).
Length = 1034
Score = 434 bits (1070), Expect = e-121
Identities = 282/834 (33%), Positives = 414/834 (49%), Gaps = 45/834 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAGGL 66
P I+EQP D+ V+R +PATL CRA G P P I WYK G V + HR +LP+G L
Sbjct: 64 PRIVEQPPDLLVSRGEPATLPCRAEGRPRPNIEWYKNGARVATVREDPRAHRLLLPSGAL 123
Query: 67 FFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
FF R HGR D GVY C A N G A SRNA+L VAVLR++FR P + A G+
Sbjct: 124 FFPRIVHGRRARPDEGVYTCVARNYLGAAASRNASLEVAVLRDDFRQSPGNVVVAVGEPA 183
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
VLEC+PPRG PEP+V W+K+G L + + R+ + GG L++ ++DAG Y C+A N
Sbjct: 184 VLECVPPRGHPEPSVSWRKDGARLK-EEEGRI-TIRGGKLMMSHTLKSDAGMYVCVASNM 241
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
AG RESA A + + +P + P + V + VTF C V GDP P + WR+ G +P
Sbjct: 242 AGERESAAAEVMVLERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRKE--DGELP 299
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
GR ++ D SL + +V DEG Y+C AENSVG ASG L+V+ PP + P
Sbjct: 300 TGRYEIRSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVPPQLVTQPQDQMAA 359
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G F C G P P +FW EG++ ++FP S +V L I + D
Sbjct: 360 PGESVAFQCETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSV-SPRGQLNITAVQRGD 418
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
+ +C AV+ AGS + L + D PP+I GP+NQTL + S PC
Sbjct: 419 A-GYYMCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGN 477
Query: 425 PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P+P + W +G+ L + + T +GTL + ++ + D G Y+CVA S G+ WSG L
Sbjct: 478 PQPSVRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLK 537
Query: 484 V--DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
+ D ++P+ + SS PG P++P+ +T S+TL+W N + G +++ Y +E
Sbjct: 538 MREDWGVSPD----PPTEPSSPPGAPSQPVVTEITKNSITLTWKPNPQTG-AAVTSYVIE 592
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
FS P W +A V + V L P Y+F+VR + GLS PSPV
Sbjct: 593 AFS---------PAAGNTWRTVADGVQLETHTVSGLQPNTIYLFLVRAVGAWGLSEPSPV 643
Query: 602 SDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN-FYY 660
S+ V D S S V + + L + V L E + +T+++ W +
Sbjct: 644 SEPVRTQDSSPS----RPVEDPWRGQQG-LAEVAVRLQEPIVLGPRTLQVSWTVDGPVQL 698
Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
++G + +R + M L S + L T+ + + ++ G S
Sbjct: 699 VQGFRVSWRVAGPEGGSWTMLD-LQSPSQQSTVLRGLPPGTQIQIKVQAQGQEGLGAESL 757
Query: 721 SRVAQTLDDVPDGPPINIEMFI--LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778
S ++ P GPP + + + +++ + W PP QNG+IT Y + W
Sbjct: 758 SVTRSIPEEAPSGPPQGVAVALGGDGNSSITVSWEPPLPSQQNGVITEYQI---W--CLG 812
Query: 779 NKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDS 831
N+S +N + A S ++ L G+ Y +AA T G+G S V + S
Sbjct: 813 NESRFHLNRSAAGWARSAMLRGLVPGLLYRTLVAAATSAGVGVPSAPVLVQLPS 866
Score = 126 bits (305), Expect = 4e-28
Identities = 102/339 (30%), Positives = 157/339 (46%), Gaps = 40/339 (11%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P + +P++ V P T C G P P +RW K LP G + +
Sbjct: 256 ERPSFLRRPVNQVVLADAPVTFLCEVKGDPPPRLRWRK---------EDGELPT-GRYEI 305
Query: 70 RATH----GRVHS-DAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGD 123
R+ H G V + D G Y C A NS G A S + ++HV + +P+ + +A G+
Sbjct: 306 RSDHSLWIGHVSAEDEGTYTCVAENSVGRAEASGSLSVHVP---PQLVTQPQDQMAAPGE 362
Query: 124 TVVLECLPPRGSPEPNVYWKKNG-QTLLFDGDS-----RMHLVDGGNLVIQDARQTDAGR 177
+V +C +G+P P ++W+K G Q LLF S R + G L I ++ DAG
Sbjct: 363 SVAFQC-ETKGNPPPAIFWQKEGSQVLLFPSQSLQPTGRFSVSPRGQLNITAVQRGDAGY 421
Query: 178 YQCIARNAAGT-RESAIATLK----IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
Y C A + AG+ A+ +K + P ++ GP + GSSV CRV G+P P
Sbjct: 422 YMCQAVSVAGSILAKALLEIKGASLDGLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPS 481
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-- 290
V W++ + K + +G+L + NV D G YSC A++S G + SG+L +
Sbjct: 482 VRWKKDGQWLQGDDLQFKTMANGTLYIANVQEMDMGFYSCVAKSSTGEATWSGWLKMRED 541
Query: 291 -----DPPSINLSPNSVNVES--GNVARFTCTATGRPEP 322
DPP+ SP + + + + T T +P P
Sbjct: 542 WGVSPDPPTEPSSPPGAPSQPVVTEITKNSITLTWKPNP 580
Score = 45.2 bits (102), Expect = 0.001
Identities = 26/86 (30%), Positives = 38/86 (44%), Gaps = 3/86 (3%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P I++ P + T+ L CR G+P P++RW K G + D + A G +
Sbjct: 448 GLPPVILQGPANQTLVLGSSVWLPCRVTGNPQPSVRWKKDGQWLQGDDLQFKTMANGTLY 507
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTA 94
+ D G Y C A +S G A
Sbjct: 508 IANVQ---EMDMGFYSCVAKSSTGEA 530
>AK074780-1|BAC11205.1| 570|Homo sapiens protein ( Homo sapiens
cDNA FLJ90299 fis, clone NT2RP2000514, highly similar to
Homo sapiens roundabout 2 (robo2) mRNA. ).
Length = 570
Score = 289 bits (710), Expect = 3e-77
Identities = 190/571 (33%), Positives = 280/571 (49%), Gaps = 39/571 (6%)
Query: 266 DEGEYSCEAENSVGAVSASGYLTV----YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
DEG Y C AEN VG + AS LTV PP + P V G F C G P+
Sbjct: 4 DEGTYMCIAENRVGKMEASATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQ 63
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
P +FW EG++ ++FP + +V LTI + ++D+ +C A+ AGS
Sbjct: 64 PAVFWQKEGSQNLLFPNQPQQPNSRCSV-SPTGDLTITNIQRSDA-GYYICQALTVAGSI 121
Query: 382 FVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI- 439
+ +L VT DRPPPII GP+NQTL + A+ C A P P+I+W EG
Sbjct: 122 LAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPG 181
Query: 440 QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAAD 499
++ R + GTL +K+L SD+GTYTCVA+S G+ WS L V + D
Sbjct: 182 RDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGETSWSAVLDV---TESGATISKNYD 238
Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
+S LPGPP+KP +VT SVTLSW Q G+ Y +E FS+ S
Sbjct: 239 LSDLPGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIEAFSQSV---------SNS 288
Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTG 619
W +A V T Y V+ L P Y+F+VR N GLS PSP+SD V D S G
Sbjct: 289 WQTVANHVKTTLYTVRGLRPNTIYLFMVRAINPQGLSDPSPMSDPVRTQDISP---PAQG 345
Query: 620 VSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-LNFYYLEGLFIYFRPLDNI--TI 676
V + + L D +V L + T+++ W + +++G + +R + T
Sbjct: 346 VDHRQVQKE--LGDVLVRLHNPVVLTPTTVQVTWTVDRQPQFIQGYRVMYRQTSGLQATS 403
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
++ + S + +L+K YE + P++ +F+G S S+ +T ++ P PP
Sbjct: 404 SWQNLDAKVPTERSAV-LVNLKKGVTYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQ 462
Query: 737 NIEMFIL---NTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA- 792
++ + + N+T++ + W PP QNGII Y + W N++ IN TV A
Sbjct: 463 SVTVLTVGSYNSTSISVSWDPPPPDHQNGIIQEYKI---W--CLGNETRFHINKTVDAAI 517
Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
S+I+ L G+ Y V++AA T G+G S+
Sbjct: 518 RSVIIGGLFPGIQYRVEVAASTSAGVGVKSE 548
Score = 92.7 bits (220), Expect = 7e-18
Identities = 76/236 (32%), Positives = 102/236 (43%), Gaps = 29/236 (12%)
Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPY----LITGPEDVVAQTGSSVTFQCRVGGD 228
TD G Y CIA N G E++ ATL + +P + P D + G +VTF C G+
Sbjct: 3 TDEGTYMCIAENRVGKMEAS-ATLTVRARPVAPPQFVVRPRDQIVAQGRTVTFPCETKGN 61
Query: 229 PLPDVLWRRSAGGGNM--------PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
P P V W++ G N+ P R V G L + N+ +D G Y C+A G+
Sbjct: 62 PQPAVFWQKE-GSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGS 120
Query: 281 VSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
+ A L V D PP I P + + A C ATG P P + W EG
Sbjct: 121 ILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEG---F 177
Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
FPG RD AT G L I + +D+ T C A + +G + L VT
Sbjct: 178 TFPG--RDP-RATIQEQG--TLQIKNLRISDT-GTYTCVATSSSGETSWSAVLDVT 227
Score = 68.5 bits (160), Expect = 1e-10
Identities = 61/197 (30%), Positives = 91/197 (46%), Gaps = 23/197 (11%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHR-----SILPA 63
P + +P D VA+ + T C G+P PA+ W K G +L + + S+ P
Sbjct: 35 PQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPT 94
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREE----FRLEPESKQ 118
G L SDAG Y C+A G+ ++ A L V VL + P ++
Sbjct: 95 GDLTITNIQ----RSDAGYYICQALTVAGSILAK-AQLEVTDVLTDRPPPIILQGPANQT 149
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGR 177
A T +L+C G P P + W K G T F G D R + + G L I++ R +D G
Sbjct: 150 LAVDGTALLKC-KATGDPLPVISWLKEGFT--FPGRDPRATIQEQGTLQIKNLRISDTGT 206
Query: 178 YQCIARNAAG-TRESAI 193
Y C+A +++G T SA+
Sbjct: 207 YTCVATSSSGETSWSAV 223
Score = 50.8 bits (116), Expect = 3e-05
Identities = 35/100 (35%), Positives = 48/100 (48%), Gaps = 4/100 (4%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D +T P I++ P + T+A A L C+A G P P I W K G R+ +
Sbjct: 131 DVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE 190
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
G L+ + R+ SD G Y C AT+S G S +A L V
Sbjct: 191 QGT--LQIKNLRI-SDTGTYTCVATSSSGET-SWSAVLDV 226
>BX538319-1|CAD98093.1| 1290|Homo sapiens hypothetical protein
protein.
Length = 1290
Score = 242 bits (592), Expect = 6e-63
Identities = 175/587 (29%), Positives = 282/587 (48%), Gaps = 50/587 (8%)
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIF---PGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
F C ATG P+P +FW EG++ ++F P S ++ + D LTI + ++D
Sbjct: 5 FQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD----LTITNVQRSDV-G 59
Query: 369 TIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
+C +N AGS + L VT DRPPP+I GP NQT+ + V C A +P P
Sbjct: 60 YYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVP 119
Query: 428 IIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
I W +G + Q+ R +G L ++ D+G YTC+AS+ G+ WS + V
Sbjct: 120 TILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQG 179
Query: 487 PINP---NIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
+N + R D + +P P+KP +V+ +VTLSW N G++ Y +E F
Sbjct: 180 KVNEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TSYIIEAF 238
Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
S SG++ W +A V +K L P Y+F+VR N++G+S PS +SD
Sbjct: 239 SH--ASGSS-------WQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISD 289
Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI-LNFYYLE 662
V D L GV + R L + ++ L T + S +I++ W + Y++
Sbjct: 290 PVKTQD---VLPTSQGVDHKQVQRE--LGNAVLHLHNPTVLSSSSIEVHWTVDQQSQYIQ 344
Query: 663 GLFIYFRPL-----DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK 717
G I +RP ++ + +E++T ++ V I LRK YE PF+ +F+G
Sbjct: 345 GYKILYRPSGANHGESDWLVFEVRTPAKNSVV----IPDLRKGVNYEIKARPFFNEFQGA 400
Query: 718 PSNSRVAQTLDDVPDGPP--INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
S + A+TL++ P PP + + N T + + W PP QNG++ Y V W
Sbjct: 401 DSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKV---W-- 455
Query: 776 VPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSV 834
N++ IN TV +T S+++ L G+ YSV++AA T G G S+ + +D+
Sbjct: 456 CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQFIQLDAHGN 515
Query: 835 GLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIY 881
+ + + ++S D V + F IGA ++V + +Y
Sbjct: 516 PVSPEDQVSLAQQIS----DVVKQPAFIAGIGAACWIILMVFSIWLY 558
Score = 80.2 bits (189), Expect = 4e-14
Identities = 52/177 (29%), Positives = 82/177 (46%), Gaps = 12/177 (6%)
Query: 124 TVVLECLPPRGSPEPNVYWKKNG-QTLLFD-----GDSRMHLVDGGNLVIQDARQTDAGR 177
TV +C G+P+P ++W++ G Q LLF SR + G+L I + +++D G
Sbjct: 2 TVTFQC-EATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGY 60
Query: 178 YQCIARNAAG---TRESAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
Y C N AG T+ T I +P + GP + + C G P+P
Sbjct: 61 YICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPT 120
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+LWR+ + R+K L++G L++ L D G Y+C A G + S Y+ V
Sbjct: 121 ILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEV 177
Score = 70.1 bits (164), Expect = 4e-11
Identities = 59/207 (28%), Positives = 84/207 (40%), Gaps = 23/207 (11%)
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--------RVKVLDDGSLRLDNVILADEGE 269
+VTFQC G+P P + WRR G N+ R V G L + NV +D G
Sbjct: 2 TVTFQCEATGNPQPAIFWRRE-GSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGY 60
Query: 270 YSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
Y C+ N G++ YL V D PP I P + V +C ATG P PT
Sbjct: 61 YICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPT 120
Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
+ W +G ++ SR K V + + DT + + ++ V
Sbjct: 121 ILWRKDG--VLVSTQDSRIKQLENGVLQ-IRYAKLGDTGRYTCIASTPSGEATWSAYIEV 177
Query: 384 RGKLT---VTSDDDRP--PPIITNGPS 405
+GK+ V RP P +I + PS
Sbjct: 178 QGKVNEFGVPVQPPRPTDPNLIPSAPS 204
Score = 67.3 bits (157), Expect = 3e-10
Identities = 55/171 (32%), Positives = 79/171 (46%), Gaps = 20/171 (11%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVV--------SDTHRSILPAGGLFFLRATHGRVHSDAG 81
T C A G+P PAI W + G + S + S+ G L SD G
Sbjct: 4 TFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQ----RSDVG 59
Query: 82 VYWCEATNSYGTARSRNATLHVA-VLREE----FRLEPESKQSAQGDTVVLECLPPRGSP 136
Y C+ N G+ ++ A L V V+ + R P ++ A T VL C+ GSP
Sbjct: 60 YYICQTLNVAGSIITK-AYLEVTDVIADRPPPVIRQGPVNQTVAVDGTFVLSCV-ATGSP 117
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
P + W+K+G L+ DSR+ ++ G L I+ A+ D GRY CIA +G
Sbjct: 118 VPTILWRKDG-VLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCIASTPSG 167
Score = 46.0 bits (104), Expect = 8e-04
Identities = 31/91 (34%), Positives = 43/91 (47%), Gaps = 3/91 (3%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + P I + P++ TVA L+C A GSP P I W K GVLV + R
Sbjct: 82 DVIADRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 141
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTA 94
G+ +R + ++ D G Y C A+ G A
Sbjct: 142 NGVLQIR--YAKL-GDTGRYTCIASTPSGEA 169
>AF156100-1|AAK68690.1| 5636|Homo sapiens hemicentin protein.
Length = 5636
Score = 206 bits (504), Expect = 3e-52
Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL
Sbjct: 3987 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4046
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126
RA V DAG Y C A N GTA + L+V V + P K+ A +
Sbjct: 4047 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4098
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A
Sbjct: 4099 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4155
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ S L +H+ P + + S C G P P + W++ L
Sbjct: 4156 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4214
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++
Sbjct: 4215 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4274
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R +C ATG P P + W+ N I P H +V +G + L I K DS
Sbjct: 4275 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4324
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
T VC+A N G G + V PP + PSN P+ A+ C P
Sbjct: 4325 -GTYVCTAENSVGFVKATGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4379
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S
Sbjct: 4380 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4439
Query: 487 P 487
P
Sbjct: 4440 P 4440
Score = 188 bits (459), Expect = 8e-47
Identities = 147/478 (30%), Positives = 211/478 (44%), Gaps = 28/478 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L
Sbjct: 3898 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3956
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C
Sbjct: 3957 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4010
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT
Sbjct: 4011 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4068
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
I L + + P + ++ V +T C G P PD+ W + G + R
Sbjct: 4069 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4126
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
+VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V +
Sbjct: 4127 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4186
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P P + W + ++ + KY A + L + + DS
Sbjct: 4187 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4237
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG LTV P T P + +L C A P P +
Sbjct: 4238 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4292
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
W F +I H +V LV++ + K DSGTY C A + G +G + V P
Sbjct: 4293 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVYVKEP 4349
Score = 186 bits (452), Expect = 6e-46
Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I P + + ++ L C A G P+P I W K G ++ + R + G
Sbjct: 3708 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3767
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+++ H +D G Y C ATN+ GT R R L V V P +
Sbjct: 3768 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3822
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N
Sbjct: 3823 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3881
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG + + L + + P + P D + + C G P P + W ++ G +
Sbjct: 3882 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3939
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++
Sbjct: 3940 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3999
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V N C ATG P P + W EG + + HA G L I+ +
Sbjct: 4000 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4051
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T +C A N AG++ + KL V + PP+I+ + + C A
Sbjct: 4052 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4105
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L
Sbjct: 4106 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4165
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
V P P I R+ + ++ I V D T ++W ++N + ++ + Y E
Sbjct: 4166 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4220
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
+ E + N +S + +A TH V
Sbjct: 4221 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4253
Score = 182 bits (443), Expect = 7e-45
Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
G P I++P DV++ TL C G P P I+W + + + S + S L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G LF L SD G Y CEA N +G +S ++ + P +G
Sbjct: 850 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
+ L C G+P P W KN LL + + + G+L I+ + D G Y C+A
Sbjct: 906 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
N AGT + + +H+ P + G + + G VT C+ G+P P V+W + +
Sbjct: 964 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
+ DGSL + + + GEY C A N+ G LTVY P + LS
Sbjct: 1023 TSSAKFSAGADGSLYVVSPEGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDLRGLS 1082
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
P ++V +G C P P + W+ E +I P R + +
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I +T +DS +C A N AG+ KL V PP I GP + + +
Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474
PC A TP P+I W G ++ + +V+N DGTL + SD+G YTCVA++ G
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Score = 178 bits (434), Expect = 9e-44
Identities = 141/487 (28%), Positives = 214/487 (43%), Gaps = 36/487 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L
Sbjct: 4077 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4136
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G DAG Y C A N G++ S T+HV R + +L
Sbjct: 4137 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4189
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG
Sbjct: 4190 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4247
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
++ +L +H+ P P DV G + C+ G PLP + W + +P
Sbjct: 4248 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4304
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V L ++ V D G Y C AENSVG V A+G++ V +PP S +E
Sbjct: 4305 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKATGFVYVKEPPVFKGDYPSNWIEPL 4364
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G P PT+ W+ +G I + + + A++ T+N+ D D
Sbjct: 4365 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4417
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG LT+ S PPIIT P + + C A P+
Sbjct: 4418 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4469
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV
Sbjct: 4470 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4523
Query: 487 PINPNIH 493
P+ +H
Sbjct: 4524 PVIVQVH 4530
Score = 174 bits (424), Expect = 1e-42
Identities = 142/463 (30%), Positives = 204/463 (44%), Gaps = 35/463 (7%)
Query: 26 HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
+ P +L C +P P + WYK G + S ILP G + L+ +V DAG Y C
Sbjct: 2793 NNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRV--LQIPRAKVE-DAGRYTC 2849
Query: 86 EATNSYGT-ARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
A N G + + + V + E + PE + ++ECL GSP P W+
Sbjct: 2850 VAVNEAGEDSLQYDVRVLVPPIIEGANSDLPEEVTVLVNKSALIECLSS-GSPAPRNSWQ 2908
Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
K+GQ LL D D L +G L I + + TD GRY C+A N AG+ + L +H+ P
Sbjct: 2909 KDGQPLLED-DHHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYF-NLNVHVPPS 2966
Query: 204 LITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
+I GP E++ + ++ C V G P PD+ W ++ + + V +L++
Sbjct: 2967 VI-GPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNXQPIKLNTNTLIVPGGRTLQIIR 3025
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSI----NLSPNSVNVESGNVARFTCTAT 317
++D GEY+C A N G LTVY PPSI + S + VNV G C +
Sbjct: 3026 AKVSDGGEYTCIAINXAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESN 3085
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
P P + W G M + H + DG +L I + +D+ VC A+N
Sbjct: 3086 AVPPPVITWYKNGR-------MITESTHVEILADG-QMLHIKKAEVSDT-GQYVCRAINV 3136
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL--PIKSMAVFPCTAICTPEPIIAW---Y 432
AG L V PP I GP + + I + C A P P IAW Y
Sbjct: 3137 AGRDDKNFHLNVYV----PPSI--EGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNY 3190
Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
E R ++ L + SDSG YTC+AS+ GK
Sbjct: 3191 KRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 3233
Score = 168 bits (409), Expect = 9e-41
Identities = 132/475 (27%), Positives = 216/475 (45%), Gaps = 39/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT
Sbjct: 1365 EQVSNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423
Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
DAG Y C+A N GT++ + + ++ F P+ V LEC
Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PKEVSVVLNRDVALEC-Q 1476
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
+G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG +
Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535
Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
I L I+I P + G D+ S + +C+ G P+P + W + G M +
Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECKTRGLPMPAITWYKD-GQPIMSSSQ 1593
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
+D G L + ++D Y+C N G S ++ VY PP I NL +P + V
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+ C A G P P + W +G P + D + A + +++ + D
Sbjct: 1654 VIAHSLTLECNAAGNPSPILTWLKDG-----VPVKANDNFRIEAGGKKLEIMSAQEID-- 1706
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
R +C A + AG ++ ++ V PP I G + + ++ C
Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
+P P I W +G+ + + + +G LV+ S++G Y C+A++ G +
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814
Score = 166 bits (404), Expect = 4e-40
Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
E P DV+V + L C A G P+P I+W K G + S +T R + A G +G
Sbjct: 3252 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3309
Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ SD G Y C ATN G R N ++V + E E + ++ +EC
Sbjct: 3310 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTYVDTSINIEC-RXT 3368
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++
Sbjct: 3369 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3426
Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
L++ P + G E++ GSS + C G P P + W R PLG
Sbjct: 3427 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3482
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
+ V G L+L D G+Y+C A N G VS L V +PP IN S ++V
Sbjct: 3483 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3542
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
N TC A+G P P M W +G P D+ G VL I+ D
Sbjct: 3543 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3594
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
+ C A + AG + V PP I T+ P + T+ C +
Sbjct: 3595 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3649
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L
Sbjct: 3650 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3709
Query: 484 VDSPINPNI 492
V+ P PNI
Sbjct: 3710 VNVP--PNI 3716
Score = 165 bits (400), Expect = 1e-39
Identities = 131/461 (28%), Positives = 210/461 (45%), Gaps = 32/461 (6%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
L+ TV P L C+A G+P P I WYK L+ T + L G + + + S
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQIIDIESAQ---IS 1984
Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G T + +HVA + V LEC RG P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P++ W K+G + + L G L + + +D GRY C+A NAAG ++ I L+
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSTQISDTGRYTCVAVNAAGEKQRDI-DLR 2099
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
+++ P ++ ++V +V C+ P P + W + G + + + ++ S
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGY-LTVYDPPSINLSP--NSVNVESGNVARFT 313
L++++ + D G Y+CEA N G Y + ++ PP+I S + V GN+
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLL 2218
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
C ++G P P + W +G+ ++ M R + G L I+ +K+D+ C
Sbjct: 2219 CESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCV 2271
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPII 429
A N AG++ L V P ITN S+ T I KS+++ C P P +
Sbjct: 2272 ASNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTV 2325
Query: 430 AWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
W +G LI+ + ++G L LK++ SD+G Y CVA
Sbjct: 2326 TWMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2366
Score = 162 bits (394), Expect = 6e-39
Identities = 142/483 (29%), Positives = 206/483 (42%), Gaps = 42/483 (8%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E P + P + + ++ C A G P P I W + +V +HR + +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G F++ DAG+Y C A+NS GT + +N+TL + + + A GD
Sbjct: 664 GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
V+EC G P P V W K L S ++D G L IQ+ + DAG Y C+A
Sbjct: 719 TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N AG R + TL + P I P DV + GS+VT C V G P P + WRR
Sbjct: 775 INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830
Query: 243 NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293
NMP+ + L G+L + N+ +D+G Y CEAEN G + + +TV P
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890
Query: 294 SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I +SP+ NV G CT G P P W I M + T DG
Sbjct: 891 LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I D C A N AG++ + V P I +G +
Sbjct: 944 --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+P + W +GE + + + + DG+L + + +SG Y C A++
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPEGEESGEYVCTATN 1055
Query: 472 RHG 474
G
Sbjct: 1056 TAG 1058
Score = 159 bits (386), Expect = 6e-38
Identities = 135/481 (28%), Positives = 204/481 (42%), Gaps = 49/481 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P ++ V R + +L C G P P + W K G ++ IL G + L+ H
Sbjct: 2300 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2356
Query: 78 SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
SD G Y C A N G T + + ++H PE+ + ++V L C G P
Sbjct: 2357 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2415
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P+ W K+G + R+ L G L + DAG+Y C+ RNAAG E I L
Sbjct: 2416 LPSTTWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2473
Query: 197 KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
+ + P+++ EDV + SVT C V G+P+P++ W + +
Sbjct: 2474 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2533
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309
L++ NV + G Y+C A + G S S L V+ P+I + +P V V +
Sbjct: 2534 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2593
Query: 310 ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
C A P T+ W +E NR I I PG G T+ +N +
Sbjct: 2594 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2640
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415
N R + C A N AG ++ V PPII G P + + +
Sbjct: 2641 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2693
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
C A P ++WY +G+ L + N+ +G TL +K+ SD+G YTCVAS+ G
Sbjct: 2694 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2753
Query: 475 K 475
+
Sbjct: 2754 E 2754
Score = 157 bits (380), Expect = 3e-37
Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV ++ A + C + GSP+P W K G ++ D H L G + + T
Sbjct: 2880 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2936
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
+D G Y C A N+ G+A+ + L+V V + E+ + + L C G P
Sbjct: 2937 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2994
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG + +L
Sbjct: 2995 PDLSWLKNXQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINXAGESKKKF-SL 3051
Query: 197 KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
+++ P + + V + G+SV+ +C P P + W ++ G V++L
Sbjct: 3052 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3110
Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310
DG L + ++D G+Y C A N G + +L VY PPSI V VE+ N
Sbjct: 3111 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3170
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC ATG P PT+ W R + + G + L I + +DS N
Sbjct: 3171 TLTCDATGIPPPTIAWLKNYKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3223
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428
C A N G + L++ + PP + PS+ ++ + C A P P+
Sbjct: 3224 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3278
Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
I W +G+ + + N TL + SD+G YTCVA++ G+
Sbjct: 3279 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3328
Score = 155 bits (376), Expect = 9e-37
Identities = 133/483 (27%), Positives = 204/483 (42%), Gaps = 35/483 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT AP I P V Q TL C G+P P RW K +++ + + ++ G
Sbjct: 884 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R D G Y C A+N GT ++ ++ V VL + + + +G
Sbjct: 944 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N
Sbjct: 998 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPEGEESGEYVCTATN 1055
Query: 185 AAGTRESAIATLKIHIKPYL---ITG-----PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
AG + + L ++++P + + G P ++ G VT C V P P + W
Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDLRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ + R L GS+++ +D G Y C A N G V+ + L V+ PP I
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
P + V+ G C A G P P + WS G+ ++ D H + DG L
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413
+I+ +D+ C A N AG+ L V +D PP T + Q
Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471
FPC A TP+P I W G L + ++ +GT LV+ + D+G Y CVA +
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEEGTLLVIASVTPYDNGEYICVAVN 1342
Query: 472 RHG 474
G
Sbjct: 1343 EAG 1345
Score = 153 bits (370), Expect = 5e-36
Identities = 131/464 (28%), Positives = 213/464 (45%), Gaps = 36/464 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V +++P L C A G P+P+I W K V + + I +G + + T + DAG
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
Y C ATN+ G + ++ LHV E LE K + + V LEC G+P
Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
P + W K+ L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L
Sbjct: 1950 PVITWYKD--NCLLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006
Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
++H+ P I+G ++VA + V +C G P P + W + + ++VL G
Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L L + ++D G Y+C A N+ G L VY PP+I +V+V C
Sbjct: 2066 RILALTSTQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ P PT+ W +G+ + PG+S + + +VL I D D+ C A
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433
N AG + K + PP I + Q I+ ++ C + P P + W
Sbjct: 2177 TNVAGKT---EKKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2233
Query: 434 EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
+G ++ + R + + G L + +KSD+ Y+CVAS+ G
Sbjct: 2234 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2277
Score = 152 bits (369), Expect = 6e-36
Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)
Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG
Sbjct: 3526 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3582
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + +V D G Y C A++ G + +HV EP + V
Sbjct: 3583 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3640
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N
Sbjct: 3641 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3697
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
AG + + L +++ P + GP+ +V S +C G P P + WR+ G
Sbjct: 3698 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3756
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++
Sbjct: 3757 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3814
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V C ATG P+P++ W G+ ++ +++ Y + G V+ +
Sbjct: 3815 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3867
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D T C+ N AG LTV + PP I + P++ + + AV CTA
Sbjct: 3868 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3922
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W G L+ + + + G + + + +G YTCVA + G
Sbjct: 3923 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3975
Score = 151 bits (367), Expect = 1e-35
Identities = 136/469 (28%), Positives = 194/469 (41%), Gaps = 34/469 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
P I P + V Q + C A G+P P I W KGG ++V H P G L +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
AT SDAG+Y C ATN GT + TLHV LEP + Q +
Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C P +G+P+P + W NG+ L L +G LVI D G Y C+A N A
Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEEGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
GT E LK+H+ P + + +V C V G P P ++W +
Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVSNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402
Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
++ +++G L+L D G YSC+A N G + V PP+I P
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPKE 1462
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V+V C G P P + W +G +F G + D VL + +
Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
+ND + C+ N AG KLT+ PP I G ++ ++ I S+ C
Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
P P I WY +G+ ++ + + + G L + SDS TYTC
Sbjct: 1570 KTRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618
Score = 151 bits (367), Expect = 1e-35
Identities = 137/477 (28%), Positives = 202/477 (42%), Gaps = 33/477 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAGGLFFL 69
AP I V V + P L C A G P+P++ W K G V S ++ +L G + L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGRILAL 2070
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+T SD G Y C A N+ G + R+ L V V E ++ V L C
Sbjct: 2071 TSTQ---ISDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC 2125
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
P P + W K+G LL + + L I+DA+ D GRY C A N AG
Sbjct: 2126 -QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKT 2183
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMP 245
E + I + P I G +++ T G+ ++ C G P P+++W++
Sbjct: 2184 EKKNYNVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDS 2242
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNS 301
+GRV++L G L++ +D YSC A N G L VY P+I S P
Sbjct: 2243 MGRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTE 2302
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ V G C G P PT+ W +G+ I K + D +L + +
Sbjct: 2303 IIVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNI 2354
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPC 419
+D+ VC AVN AG + + L+V + PP II N P N ++ K+ C
Sbjct: 2355 HVSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTC 2409
Query: 420 TAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P W+ +G + N R ++ L L D+G YTCV + G+
Sbjct: 2410 EASGIPLPSTTWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2466
Score = 151 bits (366), Expect = 1e-35
Identities = 128/454 (28%), Positives = 195/454 (42%), Gaps = 34/454 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP P I W K G L+ IL G + +V S+ G+Y C A N+
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810
Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G + T+HV + L + + V L+C+ G P P++ W K+ Q +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ G L I DAGRY C+A NAAG + I L +H P L +
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926
Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMP-LGRVKVLDDGSLRLDNV 262
+ + V +C+ G+P+P + W + +G +M L R +++D +++
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNCLLSGSTSMTFLNRGQIID-----IESA 1981
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P
Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W +G+ F + V G +L + T +D+ C AVN AG
Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSTQISDT-GRYTCVAVNAAGEKQ 2093
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
L V PP I N ++ I C + P P + W +G L++
Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148
Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+++ N L ++D D+G YTC A++ GK
Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 149 bits (361), Expect = 6e-35
Identities = 136/491 (27%), Positives = 207/491 (42%), Gaps = 33/491 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL +
Sbjct: 700 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+ T DAG Y C A N G A + TL V F EP G V L C
Sbjct: 760 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+G PEP + W++ +F S + + G L I + +D G Y C A N
Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873
Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
G +S T+ + P + P G +T C + G+P+P+ W + SA
Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++
Sbjct: 934 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G C A+G P+P++ WS +G S K+ A A DG + + +
Sbjct: 992 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPE 1042
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
+ VC+A N AG + + +LTV RP +Q P++
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDLRGLSQDKPVEISVLAGEEVTL 1099
Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
PC P PII W E + + + R G++ + + SDSG Y CVA++ G
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 477 VWSGALLVDSP 487
+ L V P
Sbjct: 1160 TQAVKLNVHVP 1170
Score = 148 bits (358), Expect = 1e-34
Identities = 121/466 (25%), Positives = 197/466 (42%), Gaps = 24/466 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV +L C + G P P + W K G V++D+ + G L+ + SDA
Sbjct: 2207 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2265
Query: 81 GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
+Y C A+N GTA+ N +++ P +G ++ LEC +G P P
Sbjct: 2266 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2324
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
V W K+G L+ + ++D G+++ +++ +D GRY C+A N AG + L +
Sbjct: 2325 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2381
Query: 199 HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
H P +I PE++ +SV+ C G PLP W + ++ V++L G
Sbjct: 2382 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSTTWFKDGWPVSLS-NSVRILSGG 2440
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
LRL + D G+Y+C N+ G L+V PP I + V V+
Sbjct: 2441 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2500
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
TC TG P P + W +G P + +H + G L I + + C
Sbjct: 2501 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2551
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A + AG L V P + T+ + S C A P I W+
Sbjct: 2552 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2611
Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477
+G L N + G TL + + + ++G Y+CVA++ G+ +
Sbjct: 2612 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2657
Score = 147 bits (355), Expect = 3e-34
Identities = 139/533 (26%), Positives = 229/533 (42%), Gaps = 34/533 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P +I+ P +VTV + A L C + + W + V +++ R A
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-EEFRLEPESKQSAQGDTVVL 127
L++ +DAG Y C ++ G S A++ + V + + P+++ G V +
Sbjct: 578 LKSVK---FNDAGEYHCMVSSEGG---SSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P+P + W N ++ G R + G L I++A DAG Y C+A N+AG
Sbjct: 632 MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T + +TL+ P L+ +++ G +C+ G P P V W + G +
Sbjct: 689 T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745
Query: 248 RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++D G L++ D G+Y+C A N G + L V PP P V++E
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362
G+ C G PEPT+ W N I F S + A+F +L + +D
Sbjct: 806 IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K T +C A N G ++ + TVT P+I PS + PCT +
Sbjct: 862 K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914
Query: 423 C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W L+QN V +DG+L ++ + D G YTCVAS+ G + +
Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
++V + P I + +S++ G P + ++ WS+ ++ S+S
Sbjct: 975 VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024
Score = 138 bits (335), Expect = 8e-32
Identities = 125/466 (26%), Positives = 184/466 (39%), Gaps = 31/466 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V +L C + P P I WYK G ++ TH IL G + ++ SD
Sbjct: 3070 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3126
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N G +N L+V V E E + V L C G P P +
Sbjct: 3127 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3184
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I
Sbjct: 3185 AWLKNYKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3243
Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
+ P + P DV G +V C G P P + W + + R++V +GS
Sbjct: 3244 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3303
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
L + + +D G+Y+C A N G L VY P+I + + V
Sbjct: 3304 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTYVDTSINI 3363
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C TG P P + W G + P S + A + ++D C
Sbjct: 3364 ECRXTGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3414
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
A N AG L V + PP + N + + + S C TP P +A
Sbjct: 3415 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3469
Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W +G+ L + H T+ L L + DSG YTC+AS+ G+
Sbjct: 3470 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3515
Score = 126 bits (304), Expect = 5e-28
Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%)
Query: 12 PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P+I+ E L DV V Q TL C G+P P I W+K G + D I+ G FL
Sbjct: 2479 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2536
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125
+ T+ +V G Y C A++ G +SR+ +L+V V + PE
Sbjct: 2537 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2594
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C P + W K+G L + + R+ L G L I +A++ +AGRY C+A N
Sbjct: 2595 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2652
Query: 186 AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
AG +K++I P + G P++V + +++T +C P + W +
Sbjct: 2653 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2711
Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295
G V + +G +L++ ++D G Y+C A N G + + PPS
Sbjct: 2712 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2770
Query: 296 ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
N+ N E+ N C P PT+ W +G+ P S DK
Sbjct: 2771 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2824
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403
+ G VL I D+ C AVN AG ++ + V PPII
Sbjct: 2825 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIEGAN 2876
Query: 404 ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459
P T+ + A+ C + +P P +W +G+ L++ +H + ++N L + +
Sbjct: 2877 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2936
Query: 460 SDSGTYTCVASSRHG 474
+D G Y CVA + G
Sbjct: 2937 TDIGRYVCVAENTAG 2951
Score = 123 bits (296), Expect = 4e-27
Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
SD G Y C A +S GT R++ V+ ++ P + G+ VL CL + +
Sbjct: 492 SDEGFYECIAVSSAGTGRAQTF-FDVSEPPPVIQV-PNNVTVTPGERAVLTCLII-SAVD 548
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
N+ W++N + + +R+ + +L ++ + DAG Y C+ + G+ +A L
Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+ P + P++ GS V+ C G P P + W + + R ++ DG+L
Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ N D G Y C A NS G + L + P + + + + V G++ C +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376
G P P + W F G + + D + +L I +T D+ C A+N
Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + GK+T+ D PP+ P++ ++ I S PC PEP I W
Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831
Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
I + +V++ G L + +L SD GTY C A ++ GK + V + P
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891
Query: 492 I 492
I
Sbjct: 892 I 892
Score = 102 bits (245), Expect = 7e-21
Identities = 93/349 (26%), Positives = 155/349 (44%), Gaps = 26/349 (7%)
Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQT--DAGRYQCIARNAAGTRESAIATLKIHIK 201
+NG TL D +L + ++ + A+ T D G Y+CIA ++AGT A +
Sbjct: 465 RNGVTLGVD----QYLKESASVSLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEP 519
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLD 260
P +I P +V G C + ++ W+R+ + R++ L + SL L
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELK 579
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+V D GEY C + G+ +AS +LTV +PP + + P + + G+ C+ATG P
Sbjct: 580 SVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYP 639
Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGS 380
+P + W+V N I + +Y T+ DG L I + D+ C A N AG+
Sbjct: 640 KPKIAWTV--NDMFI---VGSHRYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGT 689
Query: 381 SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ 440
L + P ++ S + + + V C P P + W F+G+ ++
Sbjct: 690 DKQNSTLRYI---EAPKLMVVQ--SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELR 743
Query: 441 NHRRNVTND--GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ + G L +++ D+G YTCVA + G+ L V SP
Sbjct: 744 PSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I +P++ + LNC+A G P P I W + G + D ++L
Sbjct: 4435 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4494
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
L+ A D + C A N G+ R
Sbjct: 4495 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4522
>BX928748-1|CAH74051.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone RP11-465I11 on chromosome 1. ).
Length = 5635
Score = 206 bits (502), Expect = 5e-52
Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4045
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126
RA V DAG Y C A N GTA + L+V V + P K+ A +
Sbjct: 4046 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4097
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A
Sbjct: 4098 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ S L +H+ P + + S C G P P + W++ L
Sbjct: 4155 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++
Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R +C ATG P P + W+ N I P H +V +G + L I K DS
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4323
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
T VC+A N G G + V PP + PSN P+ A+ C P
Sbjct: 4324 -GTYVCTAENSVGFVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 487 P 487
P
Sbjct: 4439 P 4439
Score = 187 bits (456), Expect = 2e-46
Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3955
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C
Sbjct: 3956 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4009
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT
Sbjct: 4010 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4067
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
I L + + P + ++ V +T C G P PD+ W + G + R
Sbjct: 4068 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4125
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
+VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V +
Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P P + W + ++ + KY A + L + + DS
Sbjct: 4186 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4236
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG LTV P T P + +L C A P P +
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
W F +I H +V LV++ + K DSGTY C A + G G + V P
Sbjct: 4292 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348
Score = 186 bits (452), Expect = 6e-46
Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I P + + ++ L C A G P+P I W K G ++ + R + G
Sbjct: 3707 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3766
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+++ H +D G Y C ATN+ GT R R L V V P +
Sbjct: 3767 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3821
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N
Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG + + L + + P + P D + + C G P P + W ++ G +
Sbjct: 3881 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3938
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++
Sbjct: 3939 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3998
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V N C ATG P P + W EG + + HA G L I+ +
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4050
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T +C A N AG++ + KL V + PP+I+ + + C A
Sbjct: 4051 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4104
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L
Sbjct: 4105 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
V P P I R+ + ++ I V D T ++W ++N + ++ + Y E
Sbjct: 4165 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4219
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
+ E + N +S + +A TH V
Sbjct: 4220 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Score = 182 bits (442), Expect = 9e-45
Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
G P I++P DV++ TL C G P P I+W + + + S + S L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G LF L SD G Y CEA N +G +S ++ + P +G
Sbjct: 850 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
+ L C G+P P W KN LL + + + G+L I+ + D G Y C+A
Sbjct: 906 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
N AGT + + +H+ P + G + + G VT C+ G+P P V+W + +
Sbjct: 964 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
+ DGSL + + + GEY C A N+ G LTVY P + LS
Sbjct: 1023 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 1082
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
P ++V +G C P P + W+ E +I P R + +
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I +T +DS +C A N AG+ KL V PP I GP + + +
Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474
PC A TP P+I W G ++ + +V+N DGTL + SD+G YTCVA++ G
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Score = 177 bits (431), Expect = 2e-43
Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G DAG Y C A N G++ S T+HV R + +L
Sbjct: 4136 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4188
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG
Sbjct: 4189 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
++ +L +H+ P P DV G + C+ G PLP + W + +P
Sbjct: 4247 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4303
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V L ++ V D G Y C AENSVG V A G++ V +PP S +E
Sbjct: 4304 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL 4363
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G P PT+ W+ +G I + + + A++ T+N+ D D
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4416
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG LT+ S PPIIT P + + C A P+
Sbjct: 4417 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4468
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV
Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4522
Query: 487 PINPNIH 493
P+ +H
Sbjct: 4523 PVIVQVH 4529
Score = 167 bits (406), Expect = 2e-40
Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
E P DV+V + L C A G P+P I+W K G + S +T R + A G +G
Sbjct: 3251 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3308
Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ SD G Y C ATN G R N ++V + E E + ++ +EC
Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 3367
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++
Sbjct: 3368 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3425
Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
L++ P + G E++ GSS + C G P P + W R PLG
Sbjct: 3426 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3481
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
+ V G L+L D G+Y+C A N G VS L V +PP IN S ++V
Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
N TC A+G P P M W +G P D+ G VL I+ D
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3593
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
+ C A + AG + V PP I T+ P + T+ C +
Sbjct: 3594 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3648
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L
Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3708
Query: 484 VDSPINPNI 492
V+ P PNI
Sbjct: 3709 VNVP--PNI 3715
Score = 165 bits (402), Expect = 6e-40
Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423
Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
DAG Y C+A N GT++ + + ++ F P V LEC
Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 1476
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
+G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG +
Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535
Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
I L I+I P + G D+ S + +C G P+P + W + G M +
Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 1593
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
+D G L + ++D Y+C N G S ++ VY PP I NL +P + V
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+ C A G P P + W +G P + D A + +++ + D
Sbjct: 1654 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 1706
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
R +C A + AG ++ ++ V PP I G + + ++ C
Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
+P P I W +G+ + + + +G LV+ S++G Y C+A++ G +
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814
Score = 165 bits (402), Expect = 6e-40
Identities = 131/460 (28%), Positives = 211/460 (45%), Gaps = 31/460 (6%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
L+ TV P L C+A G+P P I WYK L+ T + L G + + + S
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1984
Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G T + +HVA + V LEC RG P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P++ W K+G + + L G L + A+ +D GRY C+A NAAG ++ I L+
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 2099
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
+++ P ++ ++V +V C+ P P + W + G + + + ++ S
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTC 314
L++++ + D G Y+CEA N G + + ++ PP+I S + V GN+ C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
++G P P + W +G+ ++ M R + G L I+ +K+D+ C A
Sbjct: 2219 ESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCVA 2271
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPIIA 430
N AG++ L V P ITN S+ T I KS+++ C P P +
Sbjct: 2272 SNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTVT 2325
Query: 431 WYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
W +G LI+ + ++G L LK++ SD+G Y CVA
Sbjct: 2326 WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Score = 161 bits (391), Expect = 1e-38
Identities = 142/483 (29%), Positives = 205/483 (42%), Gaps = 42/483 (8%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E P + P + + ++ C A G P P I W + +V +HR + +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G F++ DAG+Y C A+NS GT + +N+TL + + + A GD
Sbjct: 664 GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
V+EC G P P V W K L S ++D G L IQ+ + DAG Y C+A
Sbjct: 719 TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N AG R + TL + P I P DV + GS+VT C V G P P + WRR
Sbjct: 775 INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830
Query: 243 NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293
NMP+ + L G+L + N+ +D+G Y CEAEN G + + +TV P
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890
Query: 294 SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I +SP+ NV G CT G P P W I M + T DG
Sbjct: 891 LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I D C A N AG++ + V P I +G +
Sbjct: 944 --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+P + W +GE + + + + DG+L + +SG Y C A++
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 472 RHG 474
G
Sbjct: 1056 TAG 1058
Score = 160 bits (389), Expect = 2e-38
Identities = 135/481 (28%), Positives = 205/481 (42%), Gaps = 49/481 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P ++ V R + +L C G P P + W K G ++ IL G + L+ H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2355
Query: 78 SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
SD G Y C A N G T + + ++H PE+ + ++V L C G P
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2414
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W K+G + R+ L G L + DAG+Y C+ RNAAG E I L
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2472
Query: 197 KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
+ + P+++ EDV + SVT C V G+P+P++ W + +
Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309
L++ NV + G Y+C A + G S S L V+ P+I + +P V V +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592
Query: 310 ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
C A P T+ W +E NR I I PG G T+ +N +
Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2639
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415
N R + C A N AG ++ V PPII G P + + +
Sbjct: 2640 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
C A P ++WY +G+ L + N+ +G TL +K+ SD+G YTCVAS+ G
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Query: 475 K 475
+
Sbjct: 2753 E 2753
Score = 156 bits (379), Expect = 4e-37
Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV ++ A + C + GSP+P W K G ++ D H L G + + T
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2935
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
+D G Y C A N+ G+A+ + L+V V + E+ + + L C G P
Sbjct: 2936 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2993
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG + +L
Sbjct: 2994 PDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF-SL 3050
Query: 197 KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
+++ P + + V + G+SV+ +C P P + W ++ G V++L
Sbjct: 3051 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3109
Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310
DG L + ++D G+Y C A N G + +L VY PPSI V VE+ N
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC ATG P PT+ W R + + G + L I + +DS N
Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3222
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428
C A N G + L++ + PP + PS+ ++ + C A P P+
Sbjct: 3223 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
I W +G+ + + N TL + SD+G YTCVA++ G+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327
Score = 155 bits (377), Expect = 7e-37
Identities = 133/483 (27%), Positives = 202/483 (41%), Gaps = 35/483 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT AP I P V Q TL C G+P P RW K +++ + + ++ G
Sbjct: 884 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R D G Y C A+N GT ++ ++ V VL + + + +G
Sbjct: 944 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N
Sbjct: 998 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 185 AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
AG + + L ++++P + P ++ G VT C V P P + W
Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ + R L GS+++ +D G Y C A N G V+ + L V+ PP I
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
P + V+ G C A G P P + WS G+ ++ D H + DG L
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413
+I+ +D+ C A N AG+ L V +D PP T + Q
Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471
FPC A TP+P I W G L + ++ DGT LV+ + D+G Y CVA +
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Query: 472 RHG 474
G
Sbjct: 1343 EAG 1345
Score = 155 bits (377), Expect = 7e-37
Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
P I P + V Q + C A G+P P I W KGG ++V H P G L +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
AT SDAG+Y C ATN GT + TLHV LEP + Q +
Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C P +G+P+P + W NG+ L L DG LVI D G Y C+A N A
Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
GT E LK+H+ P + + +V C V G P P ++W +
Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402
Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
++ +++G L+L D G YSC+A N G + V PP+I PN
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V+V C G P P + W +G +F G + D VL + +
Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
+ND + C+ N AG KLT+ PP I G ++ ++ I S+ C
Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
P P I WY +G+ ++ + + + G L + SDS TYTC
Sbjct: 1570 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618
Score = 154 bits (373), Expect = 2e-36
Identities = 130/464 (28%), Positives = 214/464 (46%), Gaps = 37/464 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V +++P L C A G P+P+I W K V + + I +G + + T + DAG
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
Y C ATN+ G + ++ LHV E LE K + + V LEC G+P
Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
P + W K+ + L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L
Sbjct: 1950 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006
Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
++H+ P I+G ++VA + V +C G P P + W + + ++VL G
Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L L + ++D G Y+C A N+ G L VY PP+I +V+V C
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ P PT+ W +G+ + PG+S + + +VL I D D+ C A
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433
N AG + + + PP I + Q I+ ++ C + P P + W
Sbjct: 2177 TNVAGKTEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232
Query: 434 EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
+G ++ + R + + G L + +KSD+ Y+CVAS+ G
Sbjct: 2233 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 152 bits (369), Expect = 6e-36
Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)
Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3581
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + +V D G Y C A++ G + +HV EP + V
Sbjct: 3582 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3639
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N
Sbjct: 3640 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
AG + + L +++ P + GP+ +V S +C G P P + WR+ G
Sbjct: 3697 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3755
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++
Sbjct: 3756 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3813
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V C ATG P+P++ W G+ ++ +++ Y + G V+ +
Sbjct: 3814 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3866
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D T C+ N AG LTV + PP I + P++ + + AV CTA
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3921
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W G L+ + + + G + + + +G YTCVA + G
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3974
Score = 151 bits (366), Expect = 1e-35
Identities = 138/476 (28%), Positives = 204/476 (42%), Gaps = 32/476 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I V V + P L C A G P+P++ W K G V S ++ + +GG L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 2069
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
T ++ SD G Y C A N+ G + R+ L V V E ++ V L C
Sbjct: 2070 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 2125
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
P P + W K+G LL + + L I+DA+ D GRY C A N AG E
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184
Query: 191 SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL 246
+ I + P I G +++ T G+ ++ C G P P+++W++ +
Sbjct: 2185 KNY-NVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242
Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302
GRV++L G L++ +D YSC A N G L VY P+I S P +
Sbjct: 2243 GRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V G C G P PT+ W +G+ I K + D +L + +
Sbjct: 2303 IVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNIH 2354
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420
+D+ VC AVN AG + + L+V + PP II N P N ++ K+ C
Sbjct: 2355 VSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 421 AICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P I W+ +G + N R ++ L L D+G YTCV + G+
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465
Score = 149 bits (362), Expect = 5e-35
Identities = 128/454 (28%), Positives = 194/454 (42%), Gaps = 34/454 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP P I W K G L+ IL G + +V S+ G+Y C A N+
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810
Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G + T+HV + L + + V L+C+ G P P++ W K+ Q +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ G L I DAGRY C+A NAAG + I L +H P L +
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926
Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262
+ + V +C+ G+P+P + W R +G +M L R +++D +++
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1981
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P
Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W +G+ F + V G +L + +D+ C AVN AG
Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 2093
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
L V PP I N ++ I C + P P + W +G L++
Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148
Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+++ N L ++D D+G YTC A++ GK
Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 149 bits (361), Expect = 6e-35
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL +
Sbjct: 700 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+ T DAG Y C A N G A + TL V F EP G V L C
Sbjct: 760 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+G PEP + W++ +F S + + G L I + +D G Y C A N
Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873
Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
G +S T+ + P + P G +T C + G+P+P+ W + SA
Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++
Sbjct: 934 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G C A+G P+P++ WS +G S K+ A A DG + +
Sbjct: 992 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 1042
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
+ VC+A N AG + + +LTV RP +Q P++
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 1099
Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
PC P PII W E + + + R G++ + + SDSG Y CVA++ G
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 477 VWSGALLVDSP 487
+ L V P
Sbjct: 1160 TQAVKLNVHVP 1170
Score = 149 bits (361), Expect = 6e-35
Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 24/466 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV +L C + G P P + W K G V++D+ + G L+ + SDA
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2264
Query: 81 GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
+Y C A+N GTA+ N +++ P +G ++ LEC +G P P
Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2323
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
V W K+G L+ + ++D G+++ +++ +D GRY C+A N AG + L +
Sbjct: 2324 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2380
Query: 199 HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
H P +I PE++ +SV+ C G PLP + W + ++ V++L G
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGG 2439
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
LRL + D G+Y+C N+ G L+V PP I + V V+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2499
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
TC TG P P + W +G P + +H + G L I + + C
Sbjct: 2500 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2550
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A + AG L V P + T+ + S C A P I W+
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610
Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477
+G L N + G TL + + + ++G Y+CVA++ G+ +
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656
Score = 147 bits (355), Expect = 3e-34
Identities = 138/533 (25%), Positives = 230/533 (43%), Gaps = 34/533 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P +I+ P +VTV + A L C + + W + V +++ R A
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127
L++ +DAG Y C ++ G++ A++ + V + + P+++ G V +
Sbjct: 578 LKSVK---FNDAGEYHCMVSSEGGSSA---ASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P+P + W N ++ G R + G L I++A DAG Y C+A N+AG
Sbjct: 632 MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T + +TL+ P L+ +++ G +C+ G P P V W + G +
Sbjct: 689 T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745
Query: 248 RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++D G L++ D G+Y+C A N G + L V PP P V++E
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362
G+ C G PEPT+ W N I F S + A+F +L + +D
Sbjct: 806 IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K T +C A N G ++ + TVT P+I PS + PCT +
Sbjct: 862 K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914
Query: 423 C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W L+QN V +DG+L ++ + D G YTCVAS+ G + +
Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
++V + P I + +S++ G P + ++ WS+ ++ S+S
Sbjct: 975 VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024
Score = 140 bits (339), Expect = 3e-32
Identities = 126/466 (27%), Positives = 185/466 (39%), Gaps = 31/466 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V +L C + P P I WYK G ++ TH IL G + ++ SD
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3125
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N G +N L+V V E E + V L C G P P +
Sbjct: 3126 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3183
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3242
Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
+ P + P DV G +V C G P P + W + + R++V +GS
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
L + + +D G+Y+C A N G L VY P+I + + V
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C ATG P P + W G + P S + A + ++D C
Sbjct: 3363 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3413
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
A N AG L V + PP + N + + + S C TP P +A
Sbjct: 3414 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W +G+ L + H T+ L L + DSG YTC+AS+ G+
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514
Score = 128 bits (309), Expect = 1e-28
Identities = 128/486 (26%), Positives = 195/486 (40%), Gaps = 50/486 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +++V +L C A G P P+I W+K G V IL G + L T
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT---TM 2449
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRG 134
DAG Y C N+ G R + L V V + E LE + Q T+ E G
Sbjct: 2450 EDAGQYTCVVRNAAGEER-KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT---G 2505
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAI 193
+P P + W K+GQ L D H++ GG L I + + GRY C+A + AG + +
Sbjct: 2506 NPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 194 ATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ L + + P + PEDV S + C P + W + G + R
Sbjct: 2564 S-LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKD--GTPLESNR 2620
Query: 249 -VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--------LS 298
+++L G +L++ N + G YSC A N G + + VY PP IN LS
Sbjct: 2621 NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P V ++ N C A P ++ W +G P S D H +G T L I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ-----PLKSDD--HVNIAANGHT-LQI 2732
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--------PIITNGPSNQTLP 410
+ +D+ C A N AG + + + NG + +
Sbjct: 2733 KEAQISDT-GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
++++ C P P + WY +G L + + + G L + D+G YTCVA
Sbjct: 2792 NNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVA 2850
Query: 470 SSRHGK 475
+ G+
Sbjct: 2851 VNEAGE 2856
Score = 126 bits (304), Expect = 5e-28
Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%)
Query: 12 PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P+I+ E L DV V Q TL C G+P P I W+K G + D I+ G FL
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2535
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125
+ T+ +V G Y C A++ G +SR+ +L+V V + PE
Sbjct: 2536 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C P + W K+G L + + R+ L G L I +A++ +AGRY C+A N
Sbjct: 2594 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2651
Query: 186 AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
AG +K++I P + G P++V + +++T +C P + W +
Sbjct: 2652 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710
Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295
G V + +G +L++ ++D G Y+C A N G + + PPS
Sbjct: 2711 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2769
Query: 296 ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
N+ N E+ N C P PT+ W +G+ P S DK
Sbjct: 2770 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2823
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403
+ G VL I D+ C AVN AG ++ + V PPII
Sbjct: 2824 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIKGAN 2875
Query: 404 ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459
P T+ + A+ C + +P P +W +G+ L++ +H + ++N L + +
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 460 SDSGTYTCVASSRHG 474
+D G Y CVA + G
Sbjct: 2936 TDIGRYVCVAENTAG 2950
Score = 123 bits (296), Expect = 4e-27
Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
SD G Y C A +S GT R++ V+ ++ P + G+ VL CL + +
Sbjct: 492 SDEGFYECIAVSSAGTGRAQ-TFFDVSEPPPVIQV-PNNVTVTPGERAVLTCL-IISAVD 548
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
N+ W++N + + +R+ + +L ++ + DAG Y C+ + G+ +A L
Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+ P + P++ GS V+ C G P P + W + + R ++ DG+L
Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ N D G Y C A NS G + L + P + + + + V G++ C +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376
G P P + W F G + + D + +L I +T D+ C A+N
Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + GK+T+ D PP+ P++ ++ I S PC PEP I W
Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831
Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
I + +V++ G L + +L SD GTY C A ++ GK + V + P
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891
Query: 492 I 492
I
Sbjct: 892 I 892
Score = 103 bits (246), Expect = 5e-21
Identities = 88/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%)
Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
NL I +D G Y+CIA ++AGT A + P +I P +V G C
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC 541
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
+ ++ W+R+ + R++ L + SL L +V D GEY C + G+ +
Sbjct: 542 LIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSA 601
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
AS +LTV +PP + + P + + G+ C+ATG P+P + W+V N I +
Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTV--NDMFI---VGSH 656
Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
+Y T+ DG L I + D+ C A N AG+ L + P ++
Sbjct: 657 RYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGTDKQNSTLRYI---EAPKLMVVQ 708
Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLKDLDKS 460
S + + + V C P P + W F+G+ ++ + + G L +++
Sbjct: 709 --SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDL 765
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G YTCVA + G+ L V SP
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I +P++ + LNC+A G P P I W + G + D ++L
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4493
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
L+ A D + C A N G+ R
Sbjct: 4494 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4521
>AL391824-1|CAI17865.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-268N14 on chromosome 1. ).
Length = 5635
Score = 206 bits (502), Expect = 5e-52
Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4045
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126
RA V DAG Y C A N GTA + L+V V + P K+ A +
Sbjct: 4046 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4097
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A
Sbjct: 4098 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ S L +H+ P + + S C G P P + W++ L
Sbjct: 4155 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++
Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R +C ATG P P + W+ N I P H +V +G + L I K DS
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4323
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
T VC+A N G G + V PP + PSN P+ A+ C P
Sbjct: 4324 -GTYVCTAENSVGFVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 487 P 487
P
Sbjct: 4439 P 4439
Score = 187 bits (456), Expect = 2e-46
Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3955
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C
Sbjct: 3956 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4009
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT
Sbjct: 4010 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4067
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
I L + + P + ++ V +T C G P PD+ W + G + R
Sbjct: 4068 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4125
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
+VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V +
Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P P + W + ++ + KY A + L + + DS
Sbjct: 4186 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4236
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG LTV P T P + +L C A P P +
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
W F +I H +V LV++ + K DSGTY C A + G G + V P
Sbjct: 4292 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348
Score = 186 bits (452), Expect = 6e-46
Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I P + + ++ L C A G P+P I W K G ++ + R + G
Sbjct: 3707 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3766
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+++ H +D G Y C ATN+ GT R R L V V P +
Sbjct: 3767 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3821
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N
Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG + + L + + P + P D + + C G P P + W ++ G +
Sbjct: 3881 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3938
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++
Sbjct: 3939 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3998
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V N C ATG P P + W EG + + HA G L I+ +
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4050
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T +C A N AG++ + KL V + PP+I+ + + C A
Sbjct: 4051 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4104
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L
Sbjct: 4105 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
V P P I R+ + ++ I V D T ++W ++N + ++ + Y E
Sbjct: 4165 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4219
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
+ E + N +S + +A TH V
Sbjct: 4220 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Score = 182 bits (442), Expect = 9e-45
Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
G P I++P DV++ TL C G P P I+W + + + S + S L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G LF L SD G Y CEA N +G +S ++ + P +G
Sbjct: 850 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
+ L C G+P P W KN LL + + + G+L I+ + D G Y C+A
Sbjct: 906 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
N AGT + + +H+ P + G + + G VT C+ G+P P V+W + +
Sbjct: 964 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
+ DGSL + + + GEY C A N+ G LTVY P + LS
Sbjct: 1023 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 1082
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
P ++V +G C P P + W+ E +I P R + +
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I +T +DS +C A N AG+ KL V PP I GP + + +
Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474
PC A TP P+I W G ++ + +V+N DGTL + SD+G YTCVA++ G
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Score = 177 bits (431), Expect = 2e-43
Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G DAG Y C A N G++ S T+HV R + +L
Sbjct: 4136 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4188
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG
Sbjct: 4189 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
++ +L +H+ P P DV G + C+ G PLP + W + +P
Sbjct: 4247 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4303
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V L ++ V D G Y C AENSVG V A G++ V +PP S +E
Sbjct: 4304 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL 4363
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G P PT+ W+ +G I + + + A++ T+N+ D D
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4416
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG LT+ S PPIIT P + + C A P+
Sbjct: 4417 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4468
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV
Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4522
Query: 487 PINPNIH 493
P+ +H
Sbjct: 4523 PVIVQVH 4529
Score = 167 bits (406), Expect = 2e-40
Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
E P DV+V + L C A G P+P I+W K G + S +T R + A G +G
Sbjct: 3251 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3308
Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ SD G Y C ATN G R N ++V + E E + ++ +EC
Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 3367
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++
Sbjct: 3368 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3425
Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
L++ P + G E++ GSS + C G P P + W R PLG
Sbjct: 3426 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3481
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
+ V G L+L D G+Y+C A N G VS L V +PP IN S ++V
Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
N TC A+G P P M W +G P D+ G VL I+ D
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3593
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
+ C A + AG + V PP I T+ P + T+ C +
Sbjct: 3594 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3648
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L
Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3708
Query: 484 VDSPINPNI 492
V+ P PNI
Sbjct: 3709 VNVP--PNI 3715
Score = 165 bits (402), Expect = 6e-40
Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423
Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
DAG Y C+A N GT++ + + ++ F P V LEC
Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 1476
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
+G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG +
Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535
Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
I L I+I P + G D+ S + +C G P+P + W + G M +
Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 1593
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
+D G L + ++D Y+C N G S ++ VY PP I NL +P + V
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+ C A G P P + W +G P + D A + +++ + D
Sbjct: 1654 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 1706
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
R +C A + AG ++ ++ V PP I G + + ++ C
Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
+P P I W +G+ + + + +G LV+ S++G Y C+A++ G +
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814
Score = 165 bits (402), Expect = 6e-40
Identities = 131/460 (28%), Positives = 211/460 (45%), Gaps = 31/460 (6%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
L+ TV P L C+A G+P P I WYK L+ T + L G + + + S
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1984
Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G T + +HVA + V LEC RG P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P++ W K+G + + L G L + A+ +D GRY C+A NAAG ++ I L+
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 2099
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
+++ P ++ ++V +V C+ P P + W + G + + + ++ S
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTC 314
L++++ + D G Y+CEA N G + + ++ PP+I S + V GN+ C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
++G P P + W +G+ ++ M R + G L I+ +K+D+ C A
Sbjct: 2219 ESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCVA 2271
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPIIA 430
N AG++ L V P ITN S+ T I KS+++ C P P +
Sbjct: 2272 SNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTVT 2325
Query: 431 WYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
W +G LI+ + ++G L LK++ SD+G Y CVA
Sbjct: 2326 WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Score = 161 bits (391), Expect = 1e-38
Identities = 142/483 (29%), Positives = 205/483 (42%), Gaps = 42/483 (8%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E P + P + + ++ C A G P P I W + +V +HR + +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G F++ DAG+Y C A+NS GT + +N+TL + + + A GD
Sbjct: 664 GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
V+EC G P P V W K L S ++D G L IQ+ + DAG Y C+A
Sbjct: 719 TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N AG R + TL + P I P DV + GS+VT C V G P P + WRR
Sbjct: 775 INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830
Query: 243 NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293
NMP+ + L G+L + N+ +D+G Y CEAEN G + + +TV P
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890
Query: 294 SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I +SP+ NV G CT G P P W I M + T DG
Sbjct: 891 LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I D C A N AG++ + V P I +G +
Sbjct: 944 --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+P + W +GE + + + + DG+L + +SG Y C A++
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 472 RHG 474
G
Sbjct: 1056 TAG 1058
Score = 160 bits (389), Expect = 2e-38
Identities = 135/481 (28%), Positives = 205/481 (42%), Gaps = 49/481 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P ++ V R + +L C G P P + W K G ++ IL G + L+ H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2355
Query: 78 SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
SD G Y C A N G T + + ++H PE+ + ++V L C G P
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2414
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W K+G + R+ L G L + DAG+Y C+ RNAAG E I L
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2472
Query: 197 KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
+ + P+++ EDV + SVT C V G+P+P++ W + +
Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309
L++ NV + G Y+C A + G S S L V+ P+I + +P V V +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592
Query: 310 ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
C A P T+ W +E NR I I PG G T+ +N +
Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2639
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415
N R + C A N AG ++ V PPII G P + + +
Sbjct: 2640 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
C A P ++WY +G+ L + N+ +G TL +K+ SD+G YTCVAS+ G
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Query: 475 K 475
+
Sbjct: 2753 E 2753
Score = 156 bits (379), Expect = 4e-37
Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV ++ A + C + GSP+P W K G ++ D H L G + + T
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2935
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
+D G Y C A N+ G+A+ + L+V V + E+ + + L C G P
Sbjct: 2936 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2993
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG + +L
Sbjct: 2994 PDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF-SL 3050
Query: 197 KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
+++ P + + V + G+SV+ +C P P + W ++ G V++L
Sbjct: 3051 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3109
Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310
DG L + ++D G+Y C A N G + +L VY PPSI V VE+ N
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC ATG P PT+ W R + + G + L I + +DS N
Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3222
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428
C A N G + L++ + PP + PS+ ++ + C A P P+
Sbjct: 3223 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
I W +G+ + + N TL + SD+G YTCVA++ G+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327
Score = 155 bits (377), Expect = 7e-37
Identities = 133/483 (27%), Positives = 202/483 (41%), Gaps = 35/483 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT AP I P V Q TL C G+P P RW K +++ + + ++ G
Sbjct: 884 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R D G Y C A+N GT ++ ++ V VL + + + +G
Sbjct: 944 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N
Sbjct: 998 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 185 AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
AG + + L ++++P + P ++ G VT C V P P + W
Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ + R L GS+++ +D G Y C A N G V+ + L V+ PP I
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
P + V+ G C A G P P + WS G+ ++ D H + DG L
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413
+I+ +D+ C A N AG+ L V +D PP T + Q
Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471
FPC A TP+P I W G L + ++ DGT LV+ + D+G Y CVA +
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Query: 472 RHG 474
G
Sbjct: 1343 EAG 1345
Score = 155 bits (377), Expect = 7e-37
Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
P I P + V Q + C A G+P P I W KGG ++V H P G L +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
AT SDAG+Y C ATN GT + TLHV LEP + Q +
Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C P +G+P+P + W NG+ L L DG LVI D G Y C+A N A
Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
GT E LK+H+ P + + +V C V G P P ++W +
Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402
Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
++ +++G L+L D G YSC+A N G + V PP+I PN
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V+V C G P P + W +G +F G + D VL + +
Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
+ND + C+ N AG KLT+ PP I G ++ ++ I S+ C
Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
P P I WY +G+ ++ + + + G L + SDS TYTC
Sbjct: 1570 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618
Score = 154 bits (373), Expect = 2e-36
Identities = 130/464 (28%), Positives = 214/464 (46%), Gaps = 37/464 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V +++P L C A G P+P+I W K V + + I +G + + T + DAG
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
Y C ATN+ G + ++ LHV E LE K + + V LEC G+P
Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
P + W K+ + L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L
Sbjct: 1950 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006
Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
++H+ P I+G ++VA + V +C G P P + W + + ++VL G
Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L L + ++D G Y+C A N+ G L VY PP+I +V+V C
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ P PT+ W +G+ + PG+S + + +VL I D D+ C A
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433
N AG + + + PP I + Q I+ ++ C + P P + W
Sbjct: 2177 TNVAGKTEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232
Query: 434 EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
+G ++ + R + + G L + +KSD+ Y+CVAS+ G
Sbjct: 2233 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 152 bits (369), Expect = 6e-36
Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)
Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3581
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + +V D G Y C A++ G + +HV EP + V
Sbjct: 3582 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3639
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N
Sbjct: 3640 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
AG + + L +++ P + GP+ +V S +C G P P + WR+ G
Sbjct: 3697 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3755
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++
Sbjct: 3756 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3813
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V C ATG P+P++ W G+ ++ +++ Y + G V+ +
Sbjct: 3814 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3866
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D T C+ N AG LTV + PP I + P++ + + AV CTA
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3921
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W G L+ + + + G + + + +G YTCVA + G
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3974
Score = 151 bits (366), Expect = 1e-35
Identities = 138/476 (28%), Positives = 204/476 (42%), Gaps = 32/476 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I V V + P L C A G P+P++ W K G V S ++ + +GG L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 2069
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
T ++ SD G Y C A N+ G + R+ L V V E ++ V L C
Sbjct: 2070 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 2125
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
P P + W K+G LL + + L I+DA+ D GRY C A N AG E
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184
Query: 191 SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL 246
+ I + P I G +++ T G+ ++ C G P P+++W++ +
Sbjct: 2185 KNY-NVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242
Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302
GRV++L G L++ +D YSC A N G L VY P+I S P +
Sbjct: 2243 GRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V G C G P PT+ W +G+ I K + D +L + +
Sbjct: 2303 IVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNIH 2354
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420
+D+ VC AVN AG + + L+V + PP II N P N ++ K+ C
Sbjct: 2355 VSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 421 AICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P I W+ +G + N R ++ L L D+G YTCV + G+
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465
Score = 149 bits (362), Expect = 5e-35
Identities = 128/454 (28%), Positives = 194/454 (42%), Gaps = 34/454 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP P I W K G L+ IL G + +V S+ G+Y C A N+
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810
Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G + T+HV + L + + V L+C+ G P P++ W K+ Q +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ G L I DAGRY C+A NAAG + I L +H P L +
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926
Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262
+ + V +C+ G+P+P + W R +G +M L R +++D +++
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1981
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P
Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W +G+ F + V G +L + +D+ C AVN AG
Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 2093
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
L V PP I N ++ I C + P P + W +G L++
Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148
Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+++ N L ++D D+G YTC A++ GK
Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 149 bits (361), Expect = 6e-35
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL +
Sbjct: 700 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+ T DAG Y C A N G A + TL V F EP G V L C
Sbjct: 760 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+G PEP + W++ +F S + + G L I + +D G Y C A N
Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873
Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
G +S T+ + P + P G +T C + G+P+P+ W + SA
Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++
Sbjct: 934 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G C A+G P+P++ WS +G S K+ A A DG + +
Sbjct: 992 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 1042
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
+ VC+A N AG + + +LTV RP +Q P++
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 1099
Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
PC P PII W E + + + R G++ + + SDSG Y CVA++ G
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 477 VWSGALLVDSP 487
+ L V P
Sbjct: 1160 TQAVKLNVHVP 1170
Score = 149 bits (361), Expect = 6e-35
Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 24/466 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV +L C + G P P + W K G V++D+ + G L+ + SDA
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2264
Query: 81 GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
+Y C A+N GTA+ N +++ P +G ++ LEC +G P P
Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2323
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
V W K+G L+ + ++D G+++ +++ +D GRY C+A N AG + L +
Sbjct: 2324 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2380
Query: 199 HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
H P +I PE++ +SV+ C G PLP + W + ++ V++L G
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGG 2439
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
LRL + D G+Y+C N+ G L+V PP I + V V+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2499
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
TC TG P P + W +G P + +H + G L I + + C
Sbjct: 2500 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2550
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A + AG L V P + T+ + S C A P I W+
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610
Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477
+G L N + G TL + + + ++G Y+CVA++ G+ +
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656
Score = 147 bits (355), Expect = 3e-34
Identities = 138/533 (25%), Positives = 230/533 (43%), Gaps = 34/533 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P +I+ P +VTV + A L C + + W + V +++ R A
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127
L++ +DAG Y C ++ G++ A++ + V + + P+++ G V +
Sbjct: 578 LKSVK---FNDAGEYHCMVSSEGGSSA---ASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P+P + W N ++ G R + G L I++A DAG Y C+A N+AG
Sbjct: 632 MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T + +TL+ P L+ +++ G +C+ G P P V W + G +
Sbjct: 689 T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745
Query: 248 RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++D G L++ D G+Y+C A N G + L V PP P V++E
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362
G+ C G PEPT+ W N I F S + A+F +L + +D
Sbjct: 806 IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K T +C A N G ++ + TVT P+I PS + PCT +
Sbjct: 862 K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914
Query: 423 C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W L+QN V +DG+L ++ + D G YTCVAS+ G + +
Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
++V + P I + +S++ G P + ++ WS+ ++ S+S
Sbjct: 975 VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024
Score = 140 bits (339), Expect = 3e-32
Identities = 126/466 (27%), Positives = 185/466 (39%), Gaps = 31/466 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V +L C + P P I WYK G ++ TH IL G + ++ SD
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3125
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N G +N L+V V E E + V L C G P P +
Sbjct: 3126 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3183
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3242
Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
+ P + P DV G +V C G P P + W + + R++V +GS
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
L + + +D G+Y+C A N G L VY P+I + + V
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C ATG P P + W G + P S + A + ++D C
Sbjct: 3363 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3413
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
A N AG L V + PP + N + + + S C TP P +A
Sbjct: 3414 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W +G+ L + H T+ L L + DSG YTC+AS+ G+
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514
Score = 128 bits (309), Expect = 1e-28
Identities = 128/486 (26%), Positives = 195/486 (40%), Gaps = 50/486 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +++V +L C A G P P+I W+K G V IL G + L T
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT---TM 2449
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRG 134
DAG Y C N+ G R + L V V + E LE + Q T+ E G
Sbjct: 2450 EDAGQYTCVVRNAAGEER-KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT---G 2505
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAI 193
+P P + W K+GQ L D H++ GG L I + + GRY C+A + AG + +
Sbjct: 2506 NPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 194 ATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ L + + P + PEDV S + C P + W + G + R
Sbjct: 2564 S-LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKD--GTPLESNR 2620
Query: 249 -VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--------LS 298
+++L G +L++ N + G YSC A N G + + VY PP IN LS
Sbjct: 2621 NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P V ++ N C A P ++ W +G P S D H +G T L I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ-----PLKSDD--HVNIAANGHT-LQI 2732
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--------PIITNGPSNQTLP 410
+ +D+ C A N AG + + + NG + +
Sbjct: 2733 KEAQISDT-GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
++++ C P P + WY +G L + + + G L + D+G YTCVA
Sbjct: 2792 NNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVA 2850
Query: 470 SSRHGK 475
+ G+
Sbjct: 2851 VNEAGE 2856
Score = 126 bits (304), Expect = 5e-28
Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%)
Query: 12 PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P+I+ E L DV V Q TL C G+P P I W+K G + D I+ G FL
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2535
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125
+ T+ +V G Y C A++ G +SR+ +L+V V + PE
Sbjct: 2536 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C P + W K+G L + + R+ L G L I +A++ +AGRY C+A N
Sbjct: 2594 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2651
Query: 186 AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
AG +K++I P + G P++V + +++T +C P + W +
Sbjct: 2652 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710
Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295
G V + +G +L++ ++D G Y+C A N G + + PPS
Sbjct: 2711 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2769
Query: 296 ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
N+ N E+ N C P PT+ W +G+ P S DK
Sbjct: 2770 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2823
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403
+ G VL I D+ C AVN AG ++ + V PPII
Sbjct: 2824 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIKGAN 2875
Query: 404 ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459
P T+ + A+ C + +P P +W +G+ L++ +H + ++N L + +
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 460 SDSGTYTCVASSRHG 474
+D G Y CVA + G
Sbjct: 2936 TDIGRYVCVAENTAG 2950
Score = 123 bits (296), Expect = 4e-27
Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
SD G Y C A +S GT R++ V+ ++ P + G+ VL CL + +
Sbjct: 492 SDEGFYECIAVSSAGTGRAQ-TFFDVSEPPPVIQV-PNNVTVTPGERAVLTCL-IISAVD 548
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
N+ W++N + + +R+ + +L ++ + DAG Y C+ + G+ +A L
Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+ P + P++ GS V+ C G P P + W + + R ++ DG+L
Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ N D G Y C A NS G + L + P + + + + V G++ C +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376
G P P + W F G + + D + +L I +T D+ C A+N
Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + GK+T+ D PP+ P++ ++ I S PC PEP I W
Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831
Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
I + +V++ G L + +L SD GTY C A ++ GK + V + P
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891
Query: 492 I 492
I
Sbjct: 892 I 892
Score = 103 bits (246), Expect = 5e-21
Identities = 88/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%)
Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
NL I +D G Y+CIA ++AGT A + P +I P +V G C
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC 541
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
+ ++ W+R+ + R++ L + SL L +V D GEY C + G+ +
Sbjct: 542 LIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSA 601
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
AS +LTV +PP + + P + + G+ C+ATG P+P + W+V N I +
Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTV--NDMFI---VGSH 656
Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
+Y T+ DG L I + D+ C A N AG+ L + P ++
Sbjct: 657 RYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGTDKQNSTLRYI---EAPKLMVVQ 708
Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLKDLDKS 460
S + + + V C P P + W F+G+ ++ + + G L +++
Sbjct: 709 --SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDL 765
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G YTCVA + G+ L V SP
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I +P++ + LNC+A G P P I W + G + D ++L
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4493
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
L+ A D + C A N G+ R
Sbjct: 4494 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4521
>AL135797-1|CAI17871.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-77J13 on chromosome 1. ).
Length = 5635
Score = 206 bits (502), Expect = 5e-52
Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4045
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126
RA V DAG Y C A N GTA + L+V V + P K+ A +
Sbjct: 4046 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4097
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A
Sbjct: 4098 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ S L +H+ P + + S C G P P + W++ L
Sbjct: 4155 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++
Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R +C ATG P P + W+ N I P H +V +G + L I K DS
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4323
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
T VC+A N G G + V PP + PSN P+ A+ C P
Sbjct: 4324 -GTYVCTAENSVGFVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 487 P 487
P
Sbjct: 4439 P 4439
Score = 187 bits (456), Expect = 2e-46
Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3955
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C
Sbjct: 3956 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4009
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT
Sbjct: 4010 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4067
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
I L + + P + ++ V +T C G P PD+ W + G + R
Sbjct: 4068 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4125
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
+VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V +
Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P P + W + ++ + KY A + L + + DS
Sbjct: 4186 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4236
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG LTV P T P + +L C A P P +
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
W F +I H +V LV++ + K DSGTY C A + G G + V P
Sbjct: 4292 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348
Score = 186 bits (452), Expect = 6e-46
Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I P + + ++ L C A G P+P I W K G ++ + R + G
Sbjct: 3707 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3766
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+++ H +D G Y C ATN+ GT R R L V V P +
Sbjct: 3767 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3821
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N
Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG + + L + + P + P D + + C G P P + W ++ G +
Sbjct: 3881 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3938
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++
Sbjct: 3939 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3998
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V N C ATG P P + W EG + + HA G L I+ +
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4050
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T +C A N AG++ + KL V + PP+I+ + + C A
Sbjct: 4051 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4104
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L
Sbjct: 4105 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
V P P I R+ + ++ I V D T ++W ++N + ++ + Y E
Sbjct: 4165 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4219
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
+ E + N +S + +A TH V
Sbjct: 4220 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Score = 182 bits (442), Expect = 9e-45
Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
G P I++P DV++ TL C G P P I+W + + + S + S L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G LF L SD G Y CEA N +G +S ++ + P +G
Sbjct: 850 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
+ L C G+P P W KN LL + + + G+L I+ + D G Y C+A
Sbjct: 906 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
N AGT + + +H+ P + G + + G VT C+ G+P P V+W + +
Sbjct: 964 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
+ DGSL + + + GEY C A N+ G LTVY P + LS
Sbjct: 1023 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 1082
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
P ++V +G C P P + W+ E +I P R + +
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I +T +DS +C A N AG+ KL V PP I GP + + +
Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474
PC A TP P+I W G ++ + +V+N DGTL + SD+G YTCVA++ G
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Score = 177 bits (431), Expect = 2e-43
Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G DAG Y C A N G++ S T+HV R + +L
Sbjct: 4136 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4188
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG
Sbjct: 4189 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
++ +L +H+ P P DV G + C+ G PLP + W + +P
Sbjct: 4247 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4303
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V L ++ V D G Y C AENSVG V A G++ V +PP S +E
Sbjct: 4304 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL 4363
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G P PT+ W+ +G I + + + A++ T+N+ D D
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4416
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG LT+ S PPIIT P + + C A P+
Sbjct: 4417 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4468
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV
Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4522
Query: 487 PINPNIH 493
P+ +H
Sbjct: 4523 PVIVQVH 4529
Score = 167 bits (406), Expect = 2e-40
Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
E P DV+V + L C A G P+P I+W K G + S +T R + A G +G
Sbjct: 3251 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3308
Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ SD G Y C ATN G R N ++V + E E + ++ +EC
Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 3367
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++
Sbjct: 3368 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3425
Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
L++ P + G E++ GSS + C G P P + W R PLG
Sbjct: 3426 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3481
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
+ V G L+L D G+Y+C A N G VS L V +PP IN S ++V
Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
N TC A+G P P M W +G P D+ G VL I+ D
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3593
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
+ C A + AG + V PP I T+ P + T+ C +
Sbjct: 3594 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3648
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L
Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3708
Query: 484 VDSPINPNI 492
V+ P PNI
Sbjct: 3709 VNVP--PNI 3715
Score = 165 bits (402), Expect = 6e-40
Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423
Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
DAG Y C+A N GT++ + + ++ F P V LEC
Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 1476
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
+G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG +
Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535
Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
I L I+I P + G D+ S + +C G P+P + W + G M +
Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 1593
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
+D G L + ++D Y+C N G S ++ VY PP I NL +P + V
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+ C A G P P + W +G P + D A + +++ + D
Sbjct: 1654 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 1706
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
R +C A + AG ++ ++ V PP I G + + ++ C
Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
+P P I W +G+ + + + +G LV+ S++G Y C+A++ G +
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814
Score = 165 bits (402), Expect = 6e-40
Identities = 131/460 (28%), Positives = 211/460 (45%), Gaps = 31/460 (6%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
L+ TV P L C+A G+P P I WYK L+ T + L G + + + S
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1984
Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G T + +HVA + V LEC RG P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P++ W K+G + + L G L + A+ +D GRY C+A NAAG ++ I L+
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 2099
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
+++ P ++ ++V +V C+ P P + W + G + + + ++ S
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTC 314
L++++ + D G Y+CEA N G + + ++ PP+I S + V GN+ C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
++G P P + W +G+ ++ M R + G L I+ +K+D+ C A
Sbjct: 2219 ESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCVA 2271
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPIIA 430
N AG++ L V P ITN S+ T I KS+++ C P P +
Sbjct: 2272 SNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTVT 2325
Query: 431 WYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
W +G LI+ + ++G L LK++ SD+G Y CVA
Sbjct: 2326 WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Score = 161 bits (391), Expect = 1e-38
Identities = 142/483 (29%), Positives = 205/483 (42%), Gaps = 42/483 (8%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E P + P + + ++ C A G P P I W + +V +HR + +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G F++ DAG+Y C A+NS GT + +N+TL + + + A GD
Sbjct: 664 GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
V+EC G P P V W K L S ++D G L IQ+ + DAG Y C+A
Sbjct: 719 TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N AG R + TL + P I P DV + GS+VT C V G P P + WRR
Sbjct: 775 INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830
Query: 243 NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293
NMP+ + L G+L + N+ +D+G Y CEAEN G + + +TV P
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890
Query: 294 SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I +SP+ NV G CT G P P W I M + T DG
Sbjct: 891 LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I D C A N AG++ + V P I +G +
Sbjct: 944 --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+P + W +GE + + + + DG+L + +SG Y C A++
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 472 RHG 474
G
Sbjct: 1056 TAG 1058
Score = 160 bits (389), Expect = 2e-38
Identities = 135/481 (28%), Positives = 205/481 (42%), Gaps = 49/481 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P ++ V R + +L C G P P + W K G ++ IL G + L+ H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2355
Query: 78 SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
SD G Y C A N G T + + ++H PE+ + ++V L C G P
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2414
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W K+G + R+ L G L + DAG+Y C+ RNAAG E I L
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2472
Query: 197 KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
+ + P+++ EDV + SVT C V G+P+P++ W + +
Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309
L++ NV + G Y+C A + G S S L V+ P+I + +P V V +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592
Query: 310 ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
C A P T+ W +E NR I I PG G T+ +N +
Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2639
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415
N R + C A N AG ++ V PPII G P + + +
Sbjct: 2640 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
C A P ++WY +G+ L + N+ +G TL +K+ SD+G YTCVAS+ G
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Query: 475 K 475
+
Sbjct: 2753 E 2753
Score = 156 bits (379), Expect = 4e-37
Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV ++ A + C + GSP+P W K G ++ D H L G + + T
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2935
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
+D G Y C A N+ G+A+ + L+V V + E+ + + L C G P
Sbjct: 2936 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2993
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG + +L
Sbjct: 2994 PDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF-SL 3050
Query: 197 KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
+++ P + + V + G+SV+ +C P P + W ++ G V++L
Sbjct: 3051 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3109
Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310
DG L + ++D G+Y C A N G + +L VY PPSI V VE+ N
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC ATG P PT+ W R + + G + L I + +DS N
Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3222
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428
C A N G + L++ + PP + PS+ ++ + C A P P+
Sbjct: 3223 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
I W +G+ + + N TL + SD+G YTCVA++ G+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327
Score = 155 bits (377), Expect = 7e-37
Identities = 133/483 (27%), Positives = 202/483 (41%), Gaps = 35/483 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT AP I P V Q TL C G+P P RW K +++ + + ++ G
Sbjct: 884 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R D G Y C A+N GT ++ ++ V VL + + + +G
Sbjct: 944 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N
Sbjct: 998 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 185 AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
AG + + L ++++P + P ++ G VT C V P P + W
Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ + R L GS+++ +D G Y C A N G V+ + L V+ PP I
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
P + V+ G C A G P P + WS G+ ++ D H + DG L
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413
+I+ +D+ C A N AG+ L V +D PP T + Q
Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471
FPC A TP+P I W G L + ++ DGT LV+ + D+G Y CVA +
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Query: 472 RHG 474
G
Sbjct: 1343 EAG 1345
Score = 155 bits (377), Expect = 7e-37
Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
P I P + V Q + C A G+P P I W KGG ++V H P G L +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
AT SDAG+Y C ATN GT + TLHV LEP + Q +
Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C P +G+P+P + W NG+ L L DG LVI D G Y C+A N A
Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
GT E LK+H+ P + + +V C V G P P ++W +
Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402
Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
++ +++G L+L D G YSC+A N G + V PP+I PN
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V+V C G P P + W +G +F G + D VL + +
Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
+ND + C+ N AG KLT+ PP I G ++ ++ I S+ C
Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
P P I WY +G+ ++ + + + G L + SDS TYTC
Sbjct: 1570 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618
Score = 154 bits (373), Expect = 2e-36
Identities = 130/464 (28%), Positives = 214/464 (46%), Gaps = 37/464 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V +++P L C A G P+P+I W K V + + I +G + + T + DAG
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
Y C ATN+ G + ++ LHV E LE K + + V LEC G+P
Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
P + W K+ + L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L
Sbjct: 1950 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006
Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
++H+ P I+G ++VA + V +C G P P + W + + ++VL G
Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L L + ++D G Y+C A N+ G L VY PP+I +V+V C
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ P PT+ W +G+ + PG+S + + +VL I D D+ C A
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433
N AG + + + PP I + Q I+ ++ C + P P + W
Sbjct: 2177 TNVAGKTEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232
Query: 434 EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
+G ++ + R + + G L + +KSD+ Y+CVAS+ G
Sbjct: 2233 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 152 bits (369), Expect = 6e-36
Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)
Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3581
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + +V D G Y C A++ G + +HV EP + V
Sbjct: 3582 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3639
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N
Sbjct: 3640 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
AG + + L +++ P + GP+ +V S +C G P P + WR+ G
Sbjct: 3697 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3755
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++
Sbjct: 3756 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3813
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V C ATG P+P++ W G+ ++ +++ Y + G V+ +
Sbjct: 3814 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3866
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D T C+ N AG LTV + PP I + P++ + + AV CTA
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3921
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W G L+ + + + G + + + +G YTCVA + G
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3974
Score = 151 bits (366), Expect = 1e-35
Identities = 138/476 (28%), Positives = 204/476 (42%), Gaps = 32/476 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I V V + P L C A G P+P++ W K G V S ++ + +GG L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 2069
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
T ++ SD G Y C A N+ G + R+ L V V E ++ V L C
Sbjct: 2070 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 2125
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
P P + W K+G LL + + L I+DA+ D GRY C A N AG E
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184
Query: 191 SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL 246
+ I + P I G +++ T G+ ++ C G P P+++W++ +
Sbjct: 2185 KNY-NVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242
Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302
GRV++L G L++ +D YSC A N G L VY P+I S P +
Sbjct: 2243 GRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V G C G P PT+ W +G+ I K + D +L + +
Sbjct: 2303 IVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNIH 2354
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420
+D+ VC AVN AG + + L+V + PP II N P N ++ K+ C
Sbjct: 2355 VSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 421 AICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P I W+ +G + N R ++ L L D+G YTCV + G+
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465
Score = 149 bits (362), Expect = 5e-35
Identities = 128/454 (28%), Positives = 194/454 (42%), Gaps = 34/454 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP P I W K G L+ IL G + +V S+ G+Y C A N+
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810
Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G + T+HV + L + + V L+C+ G P P++ W K+ Q +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ G L I DAGRY C+A NAAG + I L +H P L +
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926
Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262
+ + V +C+ G+P+P + W R +G +M L R +++D +++
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1981
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P
Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W +G+ F + V G +L + +D+ C AVN AG
Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 2093
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
L V PP I N ++ I C + P P + W +G L++
Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148
Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+++ N L ++D D+G YTC A++ GK
Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 149 bits (361), Expect = 6e-35
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL +
Sbjct: 700 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+ T DAG Y C A N G A + TL V F EP G V L C
Sbjct: 760 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+G PEP + W++ +F S + + G L I + +D G Y C A N
Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873
Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
G +S T+ + P + P G +T C + G+P+P+ W + SA
Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++
Sbjct: 934 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G C A+G P+P++ WS +G S K+ A A DG + +
Sbjct: 992 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 1042
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
+ VC+A N AG + + +LTV RP +Q P++
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 1099
Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
PC P PII W E + + + R G++ + + SDSG Y CVA++ G
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 477 VWSGALLVDSP 487
+ L V P
Sbjct: 1160 TQAVKLNVHVP 1170
Score = 149 bits (361), Expect = 6e-35
Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 24/466 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV +L C + G P P + W K G V++D+ + G L+ + SDA
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2264
Query: 81 GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
+Y C A+N GTA+ N +++ P +G ++ LEC +G P P
Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2323
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
V W K+G L+ + ++D G+++ +++ +D GRY C+A N AG + L +
Sbjct: 2324 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2380
Query: 199 HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
H P +I PE++ +SV+ C G PLP + W + ++ V++L G
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGG 2439
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
LRL + D G+Y+C N+ G L+V PP I + V V+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2499
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
TC TG P P + W +G P + +H + G L I + + C
Sbjct: 2500 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2550
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A + AG L V P + T+ + S C A P I W+
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610
Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477
+G L N + G TL + + + ++G Y+CVA++ G+ +
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656
Score = 147 bits (355), Expect = 3e-34
Identities = 138/533 (25%), Positives = 230/533 (43%), Gaps = 34/533 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P +I+ P +VTV + A L C + + W + V +++ R A
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127
L++ +DAG Y C ++ G++ A++ + V + + P+++ G V +
Sbjct: 578 LKSVK---FNDAGEYHCMVSSEGGSSA---ASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P+P + W N ++ G R + G L I++A DAG Y C+A N+AG
Sbjct: 632 MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T + +TL+ P L+ +++ G +C+ G P P V W + G +
Sbjct: 689 T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745
Query: 248 RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++D G L++ D G+Y+C A N G + L V PP P V++E
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362
G+ C G PEPT+ W N I F S + A+F +L + +D
Sbjct: 806 IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K T +C A N G ++ + TVT P+I PS + PCT +
Sbjct: 862 K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914
Query: 423 C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W L+QN V +DG+L ++ + D G YTCVAS+ G + +
Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
++V + P I + +S++ G P + ++ WS+ ++ S+S
Sbjct: 975 VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024
Score = 140 bits (339), Expect = 3e-32
Identities = 126/466 (27%), Positives = 185/466 (39%), Gaps = 31/466 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V +L C + P P I WYK G ++ TH IL G + ++ SD
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3125
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N G +N L+V V E E + V L C G P P +
Sbjct: 3126 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3183
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3242
Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
+ P + P DV G +V C G P P + W + + R++V +GS
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
L + + +D G+Y+C A N G L VY P+I + + V
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C ATG P P + W G + P S + A + ++D C
Sbjct: 3363 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3413
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
A N AG L V + PP + N + + + S C TP P +A
Sbjct: 3414 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W +G+ L + H T+ L L + DSG YTC+AS+ G+
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514
Score = 128 bits (309), Expect = 1e-28
Identities = 128/486 (26%), Positives = 195/486 (40%), Gaps = 50/486 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +++V +L C A G P P+I W+K G V IL G + L T
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT---TM 2449
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRG 134
DAG Y C N+ G R + L V V + E LE + Q T+ E G
Sbjct: 2450 EDAGQYTCVVRNAAGEER-KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT---G 2505
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAI 193
+P P + W K+GQ L D H++ GG L I + + GRY C+A + AG + +
Sbjct: 2506 NPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 194 ATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ L + + P + PEDV S + C P + W + G + R
Sbjct: 2564 S-LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKD--GTPLESNR 2620
Query: 249 -VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--------LS 298
+++L G +L++ N + G YSC A N G + + VY PP IN LS
Sbjct: 2621 NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P V ++ N C A P ++ W +G P S D H +G T L I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ-----PLKSDD--HVNIAANGHT-LQI 2732
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--------PIITNGPSNQTLP 410
+ +D+ C A N AG + + + NG + +
Sbjct: 2733 KEAQISDT-GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
++++ C P P + WY +G L + + + G L + D+G YTCVA
Sbjct: 2792 NNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVA 2850
Query: 470 SSRHGK 475
+ G+
Sbjct: 2851 VNEAGE 2856
Score = 126 bits (304), Expect = 5e-28
Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%)
Query: 12 PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P+I+ E L DV V Q TL C G+P P I W+K G + D I+ G FL
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2535
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125
+ T+ +V G Y C A++ G +SR+ +L+V V + PE
Sbjct: 2536 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C P + W K+G L + + R+ L G L I +A++ +AGRY C+A N
Sbjct: 2594 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2651
Query: 186 AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
AG +K++I P + G P++V + +++T +C P + W +
Sbjct: 2652 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710
Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295
G V + +G +L++ ++D G Y+C A N G + + PPS
Sbjct: 2711 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2769
Query: 296 ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
N+ N E+ N C P PT+ W +G+ P S DK
Sbjct: 2770 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2823
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403
+ G VL I D+ C AVN AG ++ + V PPII
Sbjct: 2824 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIKGAN 2875
Query: 404 ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459
P T+ + A+ C + +P P +W +G+ L++ +H + ++N L + +
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 460 SDSGTYTCVASSRHG 474
+D G Y CVA + G
Sbjct: 2936 TDIGRYVCVAENTAG 2950
Score = 123 bits (296), Expect = 4e-27
Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
SD G Y C A +S GT R++ V+ ++ P + G+ VL CL + +
Sbjct: 492 SDEGFYECIAVSSAGTGRAQ-TFFDVSEPPPVIQV-PNNVTVTPGERAVLTCL-IISAVD 548
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
N+ W++N + + +R+ + +L ++ + DAG Y C+ + G+ +A L
Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+ P + P++ GS V+ C G P P + W + + R ++ DG+L
Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ N D G Y C A NS G + L + P + + + + V G++ C +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376
G P P + W F G + + D + +L I +T D+ C A+N
Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + GK+T+ D PP+ P++ ++ I S PC PEP I W
Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831
Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
I + +V++ G L + +L SD GTY C A ++ GK + V + P
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891
Query: 492 I 492
I
Sbjct: 892 I 892
Score = 103 bits (246), Expect = 5e-21
Identities = 88/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%)
Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
NL I +D G Y+CIA ++AGT A + P +I P +V G C
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC 541
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
+ ++ W+R+ + R++ L + SL L +V D GEY C + G+ +
Sbjct: 542 LIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSA 601
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
AS +LTV +PP + + P + + G+ C+ATG P+P + W+V N I +
Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTV--NDMFI---VGSH 656
Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
+Y T+ DG L I + D+ C A N AG+ L + P ++
Sbjct: 657 RYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGTDKQNSTLRYI---EAPKLMVVQ 708
Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLKDLDKS 460
S + + + V C P P + W F+G+ ++ + + G L +++
Sbjct: 709 --SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDL 765
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G YTCVA + G+ L V SP
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I +P++ + LNC+A G P P I W + G + D ++L
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4493
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
L+ A D + C A N G+ R
Sbjct: 4494 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4521
>AL135796-1|CAI17854.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-164L12 on chromosome 1. ).
Length = 5635
Score = 206 bits (502), Expect = 5e-52
Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4045
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126
RA V DAG Y C A N GTA + L+V V + P K+ A +
Sbjct: 4046 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4097
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A
Sbjct: 4098 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ S L +H+ P + + S C G P P + W++ L
Sbjct: 4155 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++
Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R +C ATG P P + W+ N I P H +V +G + L I K DS
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4323
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
T VC+A N G G + V PP + PSN P+ A+ C P
Sbjct: 4324 -GTYVCTAENSVGFVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 487 P 487
P
Sbjct: 4439 P 4439
Score = 187 bits (456), Expect = 2e-46
Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3955
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C
Sbjct: 3956 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4009
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT
Sbjct: 4010 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4067
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
I L + + P + ++ V +T C G P PD+ W + G + R
Sbjct: 4068 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4125
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
+VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V +
Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P P + W + ++ + KY A + L + + DS
Sbjct: 4186 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4236
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG LTV P T P + +L C A P P +
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
W F +I H +V LV++ + K DSGTY C A + G G + V P
Sbjct: 4292 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348
Score = 186 bits (452), Expect = 6e-46
Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I P + + ++ L C A G P+P I W K G ++ + R + G
Sbjct: 3707 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3766
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+++ H +D G Y C ATN+ GT R R L V V P +
Sbjct: 3767 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3821
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N
Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG + + L + + P + P D + + C G P P + W ++ G +
Sbjct: 3881 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3938
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++
Sbjct: 3939 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3998
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V N C ATG P P + W EG + + HA G L I+ +
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4050
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T +C A N AG++ + KL V + PP+I+ + + C A
Sbjct: 4051 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4104
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L
Sbjct: 4105 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
V P P I R+ + ++ I V D T ++W ++N + ++ + Y E
Sbjct: 4165 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4219
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
+ E + N +S + +A TH V
Sbjct: 4220 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Score = 182 bits (442), Expect = 9e-45
Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
G P I++P DV++ TL C G P P I+W + + + S + S L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G LF L SD G Y CEA N +G +S ++ + P +G
Sbjct: 850 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
+ L C G+P P W KN LL + + + G+L I+ + D G Y C+A
Sbjct: 906 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
N AGT + + +H+ P + G + + G VT C+ G+P P V+W + +
Sbjct: 964 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
+ DGSL + + + GEY C A N+ G LTVY P + LS
Sbjct: 1023 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 1082
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
P ++V +G C P P + W+ E +I P R + +
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I +T +DS +C A N AG+ KL V PP I GP + + +
Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474
PC A TP P+I W G ++ + +V+N DGTL + SD+G YTCVA++ G
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Score = 177 bits (431), Expect = 2e-43
Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G DAG Y C A N G++ S T+HV R + +L
Sbjct: 4136 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4188
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG
Sbjct: 4189 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
++ +L +H+ P P DV G + C+ G PLP + W + +P
Sbjct: 4247 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4303
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V L ++ V D G Y C AENSVG V A G++ V +PP S +E
Sbjct: 4304 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL 4363
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G P PT+ W+ +G I + + + A++ T+N+ D D
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4416
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG LT+ S PPIIT P + + C A P+
Sbjct: 4417 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4468
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV
Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4522
Query: 487 PINPNIH 493
P+ +H
Sbjct: 4523 PVIVQVH 4529
Score = 167 bits (406), Expect = 2e-40
Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
E P DV+V + L C A G P+P I+W K G + S +T R + A G +G
Sbjct: 3251 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3308
Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ SD G Y C ATN G R N ++V + E E + ++ +EC
Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 3367
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++
Sbjct: 3368 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3425
Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
L++ P + G E++ GSS + C G P P + W R PLG
Sbjct: 3426 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3481
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
+ V G L+L D G+Y+C A N G VS L V +PP IN S ++V
Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
N TC A+G P P M W +G P D+ G VL I+ D
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3593
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
+ C A + AG + V PP I T+ P + T+ C +
Sbjct: 3594 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3648
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L
Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3708
Query: 484 VDSPINPNI 492
V+ P PNI
Sbjct: 3709 VNVP--PNI 3715
Score = 165 bits (402), Expect = 6e-40
Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423
Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
DAG Y C+A N GT++ + + ++ F P V LEC
Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 1476
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
+G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG +
Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535
Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
I L I+I P + G D+ S + +C G P+P + W + G M +
Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 1593
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
+D G L + ++D Y+C N G S ++ VY PP I NL +P + V
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+ C A G P P + W +G P + D A + +++ + D
Sbjct: 1654 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 1706
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
R +C A + AG ++ ++ V PP I G + + ++ C
Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
+P P I W +G+ + + + +G LV+ S++G Y C+A++ G +
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814
Score = 165 bits (402), Expect = 6e-40
Identities = 131/460 (28%), Positives = 211/460 (45%), Gaps = 31/460 (6%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
L+ TV P L C+A G+P P I WYK L+ T + L G + + + S
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1984
Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G T + +HVA + V LEC RG P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P++ W K+G + + L G L + A+ +D GRY C+A NAAG ++ I L+
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 2099
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
+++ P ++ ++V +V C+ P P + W + G + + + ++ S
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTC 314
L++++ + D G Y+CEA N G + + ++ PP+I S + V GN+ C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
++G P P + W +G+ ++ M R + G L I+ +K+D+ C A
Sbjct: 2219 ESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCVA 2271
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPIIA 430
N AG++ L V P ITN S+ T I KS+++ C P P +
Sbjct: 2272 SNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTVT 2325
Query: 431 WYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
W +G LI+ + ++G L LK++ SD+G Y CVA
Sbjct: 2326 WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Score = 161 bits (391), Expect = 1e-38
Identities = 142/483 (29%), Positives = 205/483 (42%), Gaps = 42/483 (8%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E P + P + + ++ C A G P P I W + +V +HR + +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G F++ DAG+Y C A+NS GT + +N+TL + + + A GD
Sbjct: 664 GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
V+EC G P P V W K L S ++D G L IQ+ + DAG Y C+A
Sbjct: 719 TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N AG R + TL + P I P DV + GS+VT C V G P P + WRR
Sbjct: 775 INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830
Query: 243 NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293
NMP+ + L G+L + N+ +D+G Y CEAEN G + + +TV P
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890
Query: 294 SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I +SP+ NV G CT G P P W I M + T DG
Sbjct: 891 LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I D C A N AG++ + V P I +G +
Sbjct: 944 --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+P + W +GE + + + + DG+L + +SG Y C A++
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 472 RHG 474
G
Sbjct: 1056 TAG 1058
Score = 160 bits (389), Expect = 2e-38
Identities = 135/481 (28%), Positives = 205/481 (42%), Gaps = 49/481 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P ++ V R + +L C G P P + W K G ++ IL G + L+ H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2355
Query: 78 SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
SD G Y C A N G T + + ++H PE+ + ++V L C G P
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2414
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W K+G + R+ L G L + DAG+Y C+ RNAAG E I L
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2472
Query: 197 KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
+ + P+++ EDV + SVT C V G+P+P++ W + +
Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309
L++ NV + G Y+C A + G S S L V+ P+I + +P V V +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592
Query: 310 ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
C A P T+ W +E NR I I PG G T+ +N +
Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2639
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415
N R + C A N AG ++ V PPII G P + + +
Sbjct: 2640 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
C A P ++WY +G+ L + N+ +G TL +K+ SD+G YTCVAS+ G
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Query: 475 K 475
+
Sbjct: 2753 E 2753
Score = 156 bits (379), Expect = 4e-37
Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV ++ A + C + GSP+P W K G ++ D H L G + + T
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2935
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
+D G Y C A N+ G+A+ + L+V V + E+ + + L C G P
Sbjct: 2936 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2993
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG + +L
Sbjct: 2994 PDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF-SL 3050
Query: 197 KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
+++ P + + V + G+SV+ +C P P + W ++ G V++L
Sbjct: 3051 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3109
Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310
DG L + ++D G+Y C A N G + +L VY PPSI V VE+ N
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC ATG P PT+ W R + + G + L I + +DS N
Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3222
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428
C A N G + L++ + PP + PS+ ++ + C A P P+
Sbjct: 3223 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
I W +G+ + + N TL + SD+G YTCVA++ G+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327
Score = 155 bits (377), Expect = 7e-37
Identities = 133/483 (27%), Positives = 202/483 (41%), Gaps = 35/483 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT AP I P V Q TL C G+P P RW K +++ + + ++ G
Sbjct: 884 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R D G Y C A+N GT ++ ++ V VL + + + +G
Sbjct: 944 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N
Sbjct: 998 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 185 AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
AG + + L ++++P + P ++ G VT C V P P + W
Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ + R L GS+++ +D G Y C A N G V+ + L V+ PP I
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
P + V+ G C A G P P + WS G+ ++ D H + DG L
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413
+I+ +D+ C A N AG+ L V +D PP T + Q
Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471
FPC A TP+P I W G L + ++ DGT LV+ + D+G Y CVA +
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Query: 472 RHG 474
G
Sbjct: 1343 EAG 1345
Score = 155 bits (377), Expect = 7e-37
Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
P I P + V Q + C A G+P P I W KGG ++V H P G L +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
AT SDAG+Y C ATN GT + TLHV LEP + Q +
Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C P +G+P+P + W NG+ L L DG LVI D G Y C+A N A
Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
GT E LK+H+ P + + +V C V G P P ++W +
Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402
Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
++ +++G L+L D G YSC+A N G + V PP+I PN
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V+V C G P P + W +G +F G + D VL + +
Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
+ND + C+ N AG KLT+ PP I G ++ ++ I S+ C
Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
P P I WY +G+ ++ + + + G L + SDS TYTC
Sbjct: 1570 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618
Score = 154 bits (373), Expect = 2e-36
Identities = 130/464 (28%), Positives = 214/464 (46%), Gaps = 37/464 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V +++P L C A G P+P+I W K V + + I +G + + T + DAG
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
Y C ATN+ G + ++ LHV E LE K + + V LEC G+P
Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
P + W K+ + L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L
Sbjct: 1950 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006
Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
++H+ P I+G ++VA + V +C G P P + W + + ++VL G
Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L L + ++D G Y+C A N+ G L VY PP+I +V+V C
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ P PT+ W +G+ + PG+S + + +VL I D D+ C A
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433
N AG + + + PP I + Q I+ ++ C + P P + W
Sbjct: 2177 TNVAGKTEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232
Query: 434 EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
+G ++ + R + + G L + +KSD+ Y+CVAS+ G
Sbjct: 2233 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 152 bits (369), Expect = 6e-36
Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)
Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3581
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + +V D G Y C A++ G + +HV EP + V
Sbjct: 3582 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3639
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N
Sbjct: 3640 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
AG + + L +++ P + GP+ +V S +C G P P + WR+ G
Sbjct: 3697 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3755
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++
Sbjct: 3756 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3813
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V C ATG P+P++ W G+ ++ +++ Y + G V+ +
Sbjct: 3814 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3866
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D T C+ N AG LTV + PP I + P++ + + AV CTA
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3921
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W G L+ + + + G + + + +G YTCVA + G
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3974
Score = 151 bits (366), Expect = 1e-35
Identities = 138/476 (28%), Positives = 204/476 (42%), Gaps = 32/476 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I V V + P L C A G P+P++ W K G V S ++ + +GG L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 2069
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
T ++ SD G Y C A N+ G + R+ L V V E ++ V L C
Sbjct: 2070 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 2125
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
P P + W K+G LL + + L I+DA+ D GRY C A N AG E
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184
Query: 191 SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL 246
+ I + P I G +++ T G+ ++ C G P P+++W++ +
Sbjct: 2185 KNY-NVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242
Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302
GRV++L G L++ +D YSC A N G L VY P+I S P +
Sbjct: 2243 GRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V G C G P PT+ W +G+ I K + D +L + +
Sbjct: 2303 IVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNIH 2354
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420
+D+ VC AVN AG + + L+V + PP II N P N ++ K+ C
Sbjct: 2355 VSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 421 AICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P I W+ +G + N R ++ L L D+G YTCV + G+
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465
Score = 149 bits (362), Expect = 5e-35
Identities = 128/454 (28%), Positives = 194/454 (42%), Gaps = 34/454 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP P I W K G L+ IL G + +V S+ G+Y C A N+
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810
Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G + T+HV + L + + V L+C+ G P P++ W K+ Q +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ G L I DAGRY C+A NAAG + I L +H P L +
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926
Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262
+ + V +C+ G+P+P + W R +G +M L R +++D +++
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1981
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P
Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W +G+ F + V G +L + +D+ C AVN AG
Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 2093
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
L V PP I N ++ I C + P P + W +G L++
Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148
Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+++ N L ++D D+G YTC A++ GK
Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 149 bits (361), Expect = 6e-35
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL +
Sbjct: 700 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+ T DAG Y C A N G A + TL V F EP G V L C
Sbjct: 760 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+G PEP + W++ +F S + + G L I + +D G Y C A N
Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873
Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
G +S T+ + P + P G +T C + G+P+P+ W + SA
Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++
Sbjct: 934 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G C A+G P+P++ WS +G S K+ A A DG + +
Sbjct: 992 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 1042
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
+ VC+A N AG + + +LTV RP +Q P++
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 1099
Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
PC P PII W E + + + R G++ + + SDSG Y CVA++ G
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 477 VWSGALLVDSP 487
+ L V P
Sbjct: 1160 TQAVKLNVHVP 1170
Score = 149 bits (361), Expect = 6e-35
Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 24/466 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV +L C + G P P + W K G V++D+ + G L+ + SDA
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2264
Query: 81 GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
+Y C A+N GTA+ N +++ P +G ++ LEC +G P P
Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2323
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
V W K+G L+ + ++D G+++ +++ +D GRY C+A N AG + L +
Sbjct: 2324 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2380
Query: 199 HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
H P +I PE++ +SV+ C G PLP + W + ++ V++L G
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGG 2439
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
LRL + D G+Y+C N+ G L+V PP I + V V+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2499
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
TC TG P P + W +G P + +H + G L I + + C
Sbjct: 2500 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2550
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A + AG L V P + T+ + S C A P I W+
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610
Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477
+G L N + G TL + + + ++G Y+CVA++ G+ +
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656
Score = 147 bits (355), Expect = 3e-34
Identities = 138/533 (25%), Positives = 230/533 (43%), Gaps = 34/533 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P +I+ P +VTV + A L C + + W + V +++ R A
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127
L++ +DAG Y C ++ G++ A++ + V + + P+++ G V +
Sbjct: 578 LKSVK---FNDAGEYHCMVSSEGGSSA---ASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P+P + W N ++ G R + G L I++A DAG Y C+A N+AG
Sbjct: 632 MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T + +TL+ P L+ +++ G +C+ G P P V W + G +
Sbjct: 689 T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745
Query: 248 RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++D G L++ D G+Y+C A N G + L V PP P V++E
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362
G+ C G PEPT+ W N I F S + A+F +L + +D
Sbjct: 806 IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K T +C A N G ++ + TVT P+I PS + PCT +
Sbjct: 862 K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914
Query: 423 C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W L+QN V +DG+L ++ + D G YTCVAS+ G + +
Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
++V + P I + +S++ G P + ++ WS+ ++ S+S
Sbjct: 975 VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024
Score = 140 bits (339), Expect = 3e-32
Identities = 126/466 (27%), Positives = 185/466 (39%), Gaps = 31/466 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V +L C + P P I WYK G ++ TH IL G + ++ SD
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3125
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N G +N L+V V E E + V L C G P P +
Sbjct: 3126 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3183
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3242
Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
+ P + P DV G +V C G P P + W + + R++V +GS
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
L + + +D G+Y+C A N G L VY P+I + + V
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C ATG P P + W G + P S + A + ++D C
Sbjct: 3363 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3413
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
A N AG L V + PP + N + + + S C TP P +A
Sbjct: 3414 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W +G+ L + H T+ L L + DSG YTC+AS+ G+
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514
Score = 128 bits (309), Expect = 1e-28
Identities = 128/486 (26%), Positives = 195/486 (40%), Gaps = 50/486 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +++V +L C A G P P+I W+K G V IL G + L T
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT---TM 2449
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRG 134
DAG Y C N+ G R + L V V + E LE + Q T+ E G
Sbjct: 2450 EDAGQYTCVVRNAAGEER-KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT---G 2505
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAI 193
+P P + W K+GQ L D H++ GG L I + + GRY C+A + AG + +
Sbjct: 2506 NPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 194 ATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ L + + P + PEDV S + C P + W + G + R
Sbjct: 2564 S-LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKD--GTPLESNR 2620
Query: 249 -VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--------LS 298
+++L G +L++ N + G YSC A N G + + VY PP IN LS
Sbjct: 2621 NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P V ++ N C A P ++ W +G P S D H +G T L I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ-----PLKSDD--HVNIAANGHT-LQI 2732
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--------PIITNGPSNQTLP 410
+ +D+ C A N AG + + + NG + +
Sbjct: 2733 KEAQISDT-GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
++++ C P P + WY +G L + + + G L + D+G YTCVA
Sbjct: 2792 NNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVA 2850
Query: 470 SSRHGK 475
+ G+
Sbjct: 2851 VNEAGE 2856
Score = 126 bits (304), Expect = 5e-28
Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%)
Query: 12 PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P+I+ E L DV V Q TL C G+P P I W+K G + D I+ G FL
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2535
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125
+ T+ +V G Y C A++ G +SR+ +L+V V + PE
Sbjct: 2536 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C P + W K+G L + + R+ L G L I +A++ +AGRY C+A N
Sbjct: 2594 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2651
Query: 186 AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
AG +K++I P + G P++V + +++T +C P + W +
Sbjct: 2652 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710
Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295
G V + +G +L++ ++D G Y+C A N G + + PPS
Sbjct: 2711 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2769
Query: 296 ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
N+ N E+ N C P PT+ W +G+ P S DK
Sbjct: 2770 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2823
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403
+ G VL I D+ C AVN AG ++ + V PPII
Sbjct: 2824 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIKGAN 2875
Query: 404 ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459
P T+ + A+ C + +P P +W +G+ L++ +H + ++N L + +
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 460 SDSGTYTCVASSRHG 474
+D G Y CVA + G
Sbjct: 2936 TDIGRYVCVAENTAG 2950
Score = 123 bits (296), Expect = 4e-27
Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
SD G Y C A +S GT R++ V+ ++ P + G+ VL CL + +
Sbjct: 492 SDEGFYECIAVSSAGTGRAQ-TFFDVSEPPPVIQV-PNNVTVTPGERAVLTCL-IISAVD 548
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
N+ W++N + + +R+ + +L ++ + DAG Y C+ + G+ +A L
Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+ P + P++ GS V+ C G P P + W + + R ++ DG+L
Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ N D G Y C A NS G + L + P + + + + V G++ C +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376
G P P + W F G + + D + +L I +T D+ C A+N
Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + GK+T+ D PP+ P++ ++ I S PC PEP I W
Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831
Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
I + +V++ G L + +L SD GTY C A ++ GK + V + P
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891
Query: 492 I 492
I
Sbjct: 892 I 892
Score = 103 bits (246), Expect = 5e-21
Identities = 88/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%)
Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
NL I +D G Y+CIA ++AGT A + P +I P +V G C
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC 541
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
+ ++ W+R+ + R++ L + SL L +V D GEY C + G+ +
Sbjct: 542 LIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSA 601
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
AS +LTV +PP + + P + + G+ C+ATG P+P + W+V N I +
Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTV--NDMFI---VGSH 656
Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
+Y T+ DG L I + D+ C A N AG+ L + P ++
Sbjct: 657 RYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGTDKQNSTLRYI---EAPKLMVVQ 708
Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLKDLDKS 460
S + + + V C P P + W F+G+ ++ + + G L +++
Sbjct: 709 --SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDL 765
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G YTCVA + G+ L V SP
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I +P++ + LNC+A G P P I W + G + D ++L
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4493
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
L+ A D + C A N G+ R
Sbjct: 4494 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4521
>AL133553-2|CAI17858.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-174L6 on chromosome 1. ).
Length = 5635
Score = 206 bits (502), Expect = 5e-52
Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4045
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126
RA V DAG Y C A N GTA + L+V V + P K+ A +
Sbjct: 4046 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4097
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A
Sbjct: 4098 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ S L +H+ P + + S C G P P + W++ L
Sbjct: 4155 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++
Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R +C ATG P P + W+ N I P H +V +G + L I K DS
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4323
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
T VC+A N G G + V PP + PSN P+ A+ C P
Sbjct: 4324 -GTYVCTAENSVGFVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 487 P 487
P
Sbjct: 4439 P 4439
Score = 187 bits (456), Expect = 2e-46
Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3955
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C
Sbjct: 3956 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4009
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT
Sbjct: 4010 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4067
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
I L + + P + ++ V +T C G P PD+ W + G + R
Sbjct: 4068 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4125
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
+VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V +
Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P P + W + ++ + KY A + L + + DS
Sbjct: 4186 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4236
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG LTV P T P + +L C A P P +
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
W F +I H +V LV++ + K DSGTY C A + G G + V P
Sbjct: 4292 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348
Score = 186 bits (452), Expect = 6e-46
Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I P + + ++ L C A G P+P I W K G ++ + R + G
Sbjct: 3707 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3766
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+++ H +D G Y C ATN+ GT R R L V V P +
Sbjct: 3767 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3821
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N
Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG + + L + + P + P D + + C G P P + W ++ G +
Sbjct: 3881 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3938
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++
Sbjct: 3939 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3998
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V N C ATG P P + W EG + + HA G L I+ +
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4050
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T +C A N AG++ + KL V + PP+I+ + + C A
Sbjct: 4051 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4104
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L
Sbjct: 4105 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
V P P I R+ + ++ I V D T ++W ++N + ++ + Y E
Sbjct: 4165 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4219
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
+ E + N +S + +A TH V
Sbjct: 4220 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Score = 182 bits (442), Expect = 9e-45
Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
G P I++P DV++ TL C G P P I+W + + + S + S L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G LF L SD G Y CEA N +G +S ++ + P +G
Sbjct: 850 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
+ L C G+P P W KN LL + + + G+L I+ + D G Y C+A
Sbjct: 906 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
N AGT + + +H+ P + G + + G VT C+ G+P P V+W + +
Sbjct: 964 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
+ DGSL + + + GEY C A N+ G LTVY P + LS
Sbjct: 1023 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 1082
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
P ++V +G C P P + W+ E +I P R + +
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I +T +DS +C A N AG+ KL V PP I GP + + +
Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474
PC A TP P+I W G ++ + +V+N DGTL + SD+G YTCVA++ G
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Score = 177 bits (431), Expect = 2e-43
Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G DAG Y C A N G++ S T+HV R + +L
Sbjct: 4136 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4188
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG
Sbjct: 4189 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
++ +L +H+ P P DV G + C+ G PLP + W + +P
Sbjct: 4247 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4303
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V L ++ V D G Y C AENSVG V A G++ V +PP S +E
Sbjct: 4304 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL 4363
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G P PT+ W+ +G I + + + A++ T+N+ D D
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4416
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG LT+ S PPIIT P + + C A P+
Sbjct: 4417 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4468
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV
Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4522
Query: 487 PINPNIH 493
P+ +H
Sbjct: 4523 PVIVQVH 4529
Score = 167 bits (406), Expect = 2e-40
Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
E P DV+V + L C A G P+P I+W K G + S +T R + A G +G
Sbjct: 3251 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3308
Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ SD G Y C ATN G R N ++V + E E + ++ +EC
Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 3367
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++
Sbjct: 3368 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3425
Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
L++ P + G E++ GSS + C G P P + W R PLG
Sbjct: 3426 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3481
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
+ V G L+L D G+Y+C A N G VS L V +PP IN S ++V
Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
N TC A+G P P M W +G P D+ G VL I+ D
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3593
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
+ C A + AG + V PP I T+ P + T+ C +
Sbjct: 3594 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3648
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L
Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3708
Query: 484 VDSPINPNI 492
V+ P PNI
Sbjct: 3709 VNVP--PNI 3715
Score = 165 bits (402), Expect = 6e-40
Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423
Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
DAG Y C+A N GT++ + + ++ F P V LEC
Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 1476
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
+G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG +
Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535
Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
I L I+I P + G D+ S + +C G P+P + W + G M +
Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 1593
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
+D G L + ++D Y+C N G S ++ VY PP I NL +P + V
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+ C A G P P + W +G P + D A + +++ + D
Sbjct: 1654 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 1706
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
R +C A + AG ++ ++ V PP I G + + ++ C
Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
+P P I W +G+ + + + +G LV+ S++G Y C+A++ G +
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814
Score = 165 bits (402), Expect = 6e-40
Identities = 131/460 (28%), Positives = 211/460 (45%), Gaps = 31/460 (6%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
L+ TV P L C+A G+P P I WYK L+ T + L G + + + S
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1984
Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G T + +HVA + V LEC RG P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P++ W K+G + + L G L + A+ +D GRY C+A NAAG ++ I L+
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 2099
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
+++ P ++ ++V +V C+ P P + W + G + + + ++ S
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTC 314
L++++ + D G Y+CEA N G + + ++ PP+I S + V GN+ C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
++G P P + W +G+ ++ M R + G L I+ +K+D+ C A
Sbjct: 2219 ESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCVA 2271
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPIIA 430
N AG++ L V P ITN S+ T I KS+++ C P P +
Sbjct: 2272 SNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTVT 2325
Query: 431 WYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
W +G LI+ + ++G L LK++ SD+G Y CVA
Sbjct: 2326 WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Score = 161 bits (391), Expect = 1e-38
Identities = 142/483 (29%), Positives = 205/483 (42%), Gaps = 42/483 (8%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E P + P + + ++ C A G P P I W + +V +HR + +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G F++ DAG+Y C A+NS GT + +N+TL + + + A GD
Sbjct: 664 GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
V+EC G P P V W K L S ++D G L IQ+ + DAG Y C+A
Sbjct: 719 TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N AG R + TL + P I P DV + GS+VT C V G P P + WRR
Sbjct: 775 INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830
Query: 243 NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293
NMP+ + L G+L + N+ +D+G Y CEAEN G + + +TV P
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890
Query: 294 SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I +SP+ NV G CT G P P W I M + T DG
Sbjct: 891 LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I D C A N AG++ + V P I +G +
Sbjct: 944 --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+P + W +GE + + + + DG+L + +SG Y C A++
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 472 RHG 474
G
Sbjct: 1056 TAG 1058
Score = 160 bits (389), Expect = 2e-38
Identities = 135/481 (28%), Positives = 205/481 (42%), Gaps = 49/481 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P ++ V R + +L C G P P + W K G ++ IL G + L+ H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2355
Query: 78 SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
SD G Y C A N G T + + ++H PE+ + ++V L C G P
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2414
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W K+G + R+ L G L + DAG+Y C+ RNAAG E I L
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2472
Query: 197 KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
+ + P+++ EDV + SVT C V G+P+P++ W + +
Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309
L++ NV + G Y+C A + G S S L V+ P+I + +P V V +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592
Query: 310 ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
C A P T+ W +E NR I I PG G T+ +N +
Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2639
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415
N R + C A N AG ++ V PPII G P + + +
Sbjct: 2640 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
C A P ++WY +G+ L + N+ +G TL +K+ SD+G YTCVAS+ G
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Query: 475 K 475
+
Sbjct: 2753 E 2753
Score = 156 bits (379), Expect = 4e-37
Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV ++ A + C + GSP+P W K G ++ D H L G + + T
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2935
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
+D G Y C A N+ G+A+ + L+V V + E+ + + L C G P
Sbjct: 2936 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2993
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG + +L
Sbjct: 2994 PDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF-SL 3050
Query: 197 KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
+++ P + + V + G+SV+ +C P P + W ++ G V++L
Sbjct: 3051 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3109
Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310
DG L + ++D G+Y C A N G + +L VY PPSI V VE+ N
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC ATG P PT+ W R + + G + L I + +DS N
Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3222
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428
C A N G + L++ + PP + PS+ ++ + C A P P+
Sbjct: 3223 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
I W +G+ + + N TL + SD+G YTCVA++ G+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327
Score = 155 bits (377), Expect = 7e-37
Identities = 133/483 (27%), Positives = 202/483 (41%), Gaps = 35/483 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT AP I P V Q TL C G+P P RW K +++ + + ++ G
Sbjct: 884 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R D G Y C A+N GT ++ ++ V VL + + + +G
Sbjct: 944 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N
Sbjct: 998 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 185 AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
AG + + L ++++P + P ++ G VT C V P P + W
Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ + R L GS+++ +D G Y C A N G V+ + L V+ PP I
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
P + V+ G C A G P P + WS G+ ++ D H + DG L
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413
+I+ +D+ C A N AG+ L V +D PP T + Q
Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471
FPC A TP+P I W G L + ++ DGT LV+ + D+G Y CVA +
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Query: 472 RHG 474
G
Sbjct: 1343 EAG 1345
Score = 155 bits (377), Expect = 7e-37
Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
P I P + V Q + C A G+P P I W KGG ++V H P G L +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
AT SDAG+Y C ATN GT + TLHV LEP + Q +
Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C P +G+P+P + W NG+ L L DG LVI D G Y C+A N A
Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
GT E LK+H+ P + + +V C V G P P ++W +
Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402
Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
++ +++G L+L D G YSC+A N G + V PP+I PN
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V+V C G P P + W +G +F G + D VL + +
Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
+ND + C+ N AG KLT+ PP I G ++ ++ I S+ C
Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
P P I WY +G+ ++ + + + G L + SDS TYTC
Sbjct: 1570 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618
Score = 154 bits (373), Expect = 2e-36
Identities = 130/464 (28%), Positives = 214/464 (46%), Gaps = 37/464 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V +++P L C A G P+P+I W K V + + I +G + + T + DAG
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
Y C ATN+ G + ++ LHV E LE K + + V LEC G+P
Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
P + W K+ + L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L
Sbjct: 1950 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006
Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
++H+ P I+G ++VA + V +C G P P + W + + ++VL G
Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L L + ++D G Y+C A N+ G L VY PP+I +V+V C
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ P PT+ W +G+ + PG+S + + +VL I D D+ C A
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433
N AG + + + PP I + Q I+ ++ C + P P + W
Sbjct: 2177 TNVAGKTEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232
Query: 434 EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
+G ++ + R + + G L + +KSD+ Y+CVAS+ G
Sbjct: 2233 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 152 bits (369), Expect = 6e-36
Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)
Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3581
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + +V D G Y C A++ G + +HV EP + V
Sbjct: 3582 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3639
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N
Sbjct: 3640 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
AG + + L +++ P + GP+ +V S +C G P P + WR+ G
Sbjct: 3697 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3755
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++
Sbjct: 3756 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3813
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V C ATG P+P++ W G+ ++ +++ Y + G V+ +
Sbjct: 3814 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3866
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D T C+ N AG LTV + PP I + P++ + + AV CTA
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3921
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W G L+ + + + G + + + +G YTCVA + G
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3974
Score = 151 bits (366), Expect = 1e-35
Identities = 138/476 (28%), Positives = 204/476 (42%), Gaps = 32/476 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I V V + P L C A G P+P++ W K G V S ++ + +GG L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 2069
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
T ++ SD G Y C A N+ G + R+ L V V E ++ V L C
Sbjct: 2070 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 2125
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
P P + W K+G LL + + L I+DA+ D GRY C A N AG E
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184
Query: 191 SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL 246
+ I + P I G +++ T G+ ++ C G P P+++W++ +
Sbjct: 2185 KNY-NVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242
Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302
GRV++L G L++ +D YSC A N G L VY P+I S P +
Sbjct: 2243 GRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V G C G P PT+ W +G+ I K + D +L + +
Sbjct: 2303 IVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNIH 2354
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420
+D+ VC AVN AG + + L+V + PP II N P N ++ K+ C
Sbjct: 2355 VSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 421 AICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P I W+ +G + N R ++ L L D+G YTCV + G+
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465
Score = 149 bits (362), Expect = 5e-35
Identities = 128/454 (28%), Positives = 194/454 (42%), Gaps = 34/454 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP P I W K G L+ IL G + +V S+ G+Y C A N+
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810
Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G + T+HV + L + + V L+C+ G P P++ W K+ Q +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ G L I DAGRY C+A NAAG + I L +H P L +
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926
Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262
+ + V +C+ G+P+P + W R +G +M L R +++D +++
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1981
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P
Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W +G+ F + V G +L + +D+ C AVN AG
Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 2093
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
L V PP I N ++ I C + P P + W +G L++
Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148
Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+++ N L ++D D+G YTC A++ GK
Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 149 bits (361), Expect = 6e-35
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL +
Sbjct: 700 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+ T DAG Y C A N G A + TL V F EP G V L C
Sbjct: 760 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+G PEP + W++ +F S + + G L I + +D G Y C A N
Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873
Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
G +S T+ + P + P G +T C + G+P+P+ W + SA
Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++
Sbjct: 934 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G C A+G P+P++ WS +G S K+ A A DG + +
Sbjct: 992 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 1042
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
+ VC+A N AG + + +LTV RP +Q P++
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 1099
Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
PC P PII W E + + + R G++ + + SDSG Y CVA++ G
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 477 VWSGALLVDSP 487
+ L V P
Sbjct: 1160 TQAVKLNVHVP 1170
Score = 149 bits (361), Expect = 6e-35
Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 24/466 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV +L C + G P P + W K G V++D+ + G L+ + SDA
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2264
Query: 81 GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
+Y C A+N GTA+ N +++ P +G ++ LEC +G P P
Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2323
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
V W K+G L+ + ++D G+++ +++ +D GRY C+A N AG + L +
Sbjct: 2324 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2380
Query: 199 HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
H P +I PE++ +SV+ C G PLP + W + ++ V++L G
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGG 2439
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
LRL + D G+Y+C N+ G L+V PP I + V V+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2499
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
TC TG P P + W +G P + +H + G L I + + C
Sbjct: 2500 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2550
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A + AG L V P + T+ + S C A P I W+
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610
Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477
+G L N + G TL + + + ++G Y+CVA++ G+ +
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656
Score = 147 bits (355), Expect = 3e-34
Identities = 138/533 (25%), Positives = 230/533 (43%), Gaps = 34/533 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P +I+ P +VTV + A L C + + W + V +++ R A
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127
L++ +DAG Y C ++ G++ A++ + V + + P+++ G V +
Sbjct: 578 LKSVK---FNDAGEYHCMVSSEGGSSA---ASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P+P + W N ++ G R + G L I++A DAG Y C+A N+AG
Sbjct: 632 MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T + +TL+ P L+ +++ G +C+ G P P V W + G +
Sbjct: 689 T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745
Query: 248 RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++D G L++ D G+Y+C A N G + L V PP P V++E
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362
G+ C G PEPT+ W N I F S + A+F +L + +D
Sbjct: 806 IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K T +C A N G ++ + TVT P+I PS + PCT +
Sbjct: 862 K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914
Query: 423 C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W L+QN V +DG+L ++ + D G YTCVAS+ G + +
Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
++V + P I + +S++ G P + ++ WS+ ++ S+S
Sbjct: 975 VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024
Score = 140 bits (339), Expect = 3e-32
Identities = 126/466 (27%), Positives = 185/466 (39%), Gaps = 31/466 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V +L C + P P I WYK G ++ TH IL G + ++ SD
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3125
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N G +N L+V V E E + V L C G P P +
Sbjct: 3126 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3183
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3242
Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
+ P + P DV G +V C G P P + W + + R++V +GS
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
L + + +D G+Y+C A N G L VY P+I + + V
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C ATG P P + W G + P S + A + ++D C
Sbjct: 3363 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3413
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
A N AG L V + PP + N + + + S C TP P +A
Sbjct: 3414 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W +G+ L + H T+ L L + DSG YTC+AS+ G+
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514
Score = 128 bits (309), Expect = 1e-28
Identities = 128/486 (26%), Positives = 195/486 (40%), Gaps = 50/486 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +++V +L C A G P P+I W+K G V IL G + L T
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT---TM 2449
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRG 134
DAG Y C N+ G R + L V V + E LE + Q T+ E G
Sbjct: 2450 EDAGQYTCVVRNAAGEER-KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT---G 2505
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAI 193
+P P + W K+GQ L D H++ GG L I + + GRY C+A + AG + +
Sbjct: 2506 NPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 194 ATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ L + + P + PEDV S + C P + W + G + R
Sbjct: 2564 S-LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKD--GTPLESNR 2620
Query: 249 -VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--------LS 298
+++L G +L++ N + G YSC A N G + + VY PP IN LS
Sbjct: 2621 NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P V ++ N C A P ++ W +G P S D H +G T L I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ-----PLKSDD--HVNIAANGHT-LQI 2732
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--------PIITNGPSNQTLP 410
+ +D+ C A N AG + + + NG + +
Sbjct: 2733 KEAQISDT-GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
++++ C P P + WY +G L + + + G L + D+G YTCVA
Sbjct: 2792 NNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVA 2850
Query: 470 SSRHGK 475
+ G+
Sbjct: 2851 VNEAGE 2856
Score = 126 bits (304), Expect = 5e-28
Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%)
Query: 12 PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P+I+ E L DV V Q TL C G+P P I W+K G + D I+ G FL
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2535
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125
+ T+ +V G Y C A++ G +SR+ +L+V V + PE
Sbjct: 2536 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C P + W K+G L + + R+ L G L I +A++ +AGRY C+A N
Sbjct: 2594 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2651
Query: 186 AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
AG +K++I P + G P++V + +++T +C P + W +
Sbjct: 2652 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710
Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295
G V + +G +L++ ++D G Y+C A N G + + PPS
Sbjct: 2711 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2769
Query: 296 ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
N+ N E+ N C P PT+ W +G+ P S DK
Sbjct: 2770 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2823
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403
+ G VL I D+ C AVN AG ++ + V PPII
Sbjct: 2824 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIKGAN 2875
Query: 404 ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459
P T+ + A+ C + +P P +W +G+ L++ +H + ++N L + +
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 460 SDSGTYTCVASSRHG 474
+D G Y CVA + G
Sbjct: 2936 TDIGRYVCVAENTAG 2950
Score = 123 bits (296), Expect = 4e-27
Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
SD G Y C A +S GT R++ V+ ++ P + G+ VL CL + +
Sbjct: 492 SDEGFYECIAVSSAGTGRAQ-TFFDVSEPPPVIQV-PNNVTVTPGERAVLTCL-IISAVD 548
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
N+ W++N + + +R+ + +L ++ + DAG Y C+ + G+ +A L
Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+ P + P++ GS V+ C G P P + W + + R ++ DG+L
Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ N D G Y C A NS G + L + P + + + + V G++ C +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376
G P P + W F G + + D + +L I +T D+ C A+N
Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + GK+T+ D PP+ P++ ++ I S PC PEP I W
Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831
Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
I + +V++ G L + +L SD GTY C A ++ GK + V + P
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891
Query: 492 I 492
I
Sbjct: 892 I 892
Score = 103 bits (246), Expect = 5e-21
Identities = 88/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%)
Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
NL I +D G Y+CIA ++AGT A + P +I P +V G C
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC 541
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
+ ++ W+R+ + R++ L + SL L +V D GEY C + G+ +
Sbjct: 542 LIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSA 601
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
AS +LTV +PP + + P + + G+ C+ATG P+P + W+V N I +
Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTV--NDMFI---VGSH 656
Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
+Y T+ DG L I + D+ C A N AG+ L + P ++
Sbjct: 657 RYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGTDKQNSTLRYI---EAPKLMVVQ 708
Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLKDLDKS 460
S + + + V C P P + W F+G+ ++ + + G L +++
Sbjct: 709 --SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDL 765
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G YTCVA + G+ L V SP
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I +P++ + LNC+A G P P I W + G + D ++L
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4493
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
L+ A D + C A N G+ R
Sbjct: 4494 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4521
>AL133515-1|CAI17853.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-153O3 on chromosome 1. ).
Length = 5635
Score = 206 bits (502), Expect = 5e-52
Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4045
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126
RA V DAG Y C A N GTA + L+V V + P K+ A +
Sbjct: 4046 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4097
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A
Sbjct: 4098 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ S L +H+ P + + S C G P P + W++ L
Sbjct: 4155 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++
Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R +C ATG P P + W+ N I P H +V +G + L I K DS
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4323
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
T VC+A N G G + V PP + PSN P+ A+ C P
Sbjct: 4324 -GTYVCTAENSVGFVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 487 P 487
P
Sbjct: 4439 P 4439
Score = 187 bits (456), Expect = 2e-46
Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3955
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C
Sbjct: 3956 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4009
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT
Sbjct: 4010 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4067
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
I L + + P + ++ V +T C G P PD+ W + G + R
Sbjct: 4068 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4125
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
+VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V +
Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P P + W + ++ + KY A + L + + DS
Sbjct: 4186 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4236
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG LTV P T P + +L C A P P +
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
W F +I H +V LV++ + K DSGTY C A + G G + V P
Sbjct: 4292 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348
Score = 186 bits (452), Expect = 6e-46
Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I P + + ++ L C A G P+P I W K G ++ + R + G
Sbjct: 3707 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3766
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+++ H +D G Y C ATN+ GT R R L V V P +
Sbjct: 3767 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3821
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N
Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG + + L + + P + P D + + C G P P + W ++ G +
Sbjct: 3881 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3938
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++
Sbjct: 3939 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3998
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V N C ATG P P + W EG + + HA G L I+ +
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4050
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T +C A N AG++ + KL V + PP+I+ + + C A
Sbjct: 4051 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4104
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L
Sbjct: 4105 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
V P P I R+ + ++ I V D T ++W ++N + ++ + Y E
Sbjct: 4165 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4219
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
+ E + N +S + +A TH V
Sbjct: 4220 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Score = 182 bits (442), Expect = 9e-45
Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
G P I++P DV++ TL C G P P I+W + + + S + S L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G LF L SD G Y CEA N +G +S ++ + P +G
Sbjct: 850 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
+ L C G+P P W KN LL + + + G+L I+ + D G Y C+A
Sbjct: 906 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
N AGT + + +H+ P + G + + G VT C+ G+P P V+W + +
Sbjct: 964 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
+ DGSL + + + GEY C A N+ G LTVY P + LS
Sbjct: 1023 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 1082
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
P ++V +G C P P + W+ E +I P R + +
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I +T +DS +C A N AG+ KL V PP I GP + + +
Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474
PC A TP P+I W G ++ + +V+N DGTL + SD+G YTCVA++ G
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Score = 177 bits (431), Expect = 2e-43
Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G DAG Y C A N G++ S T+HV R + +L
Sbjct: 4136 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4188
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG
Sbjct: 4189 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
++ +L +H+ P P DV G + C+ G PLP + W + +P
Sbjct: 4247 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4303
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V L ++ V D G Y C AENSVG V A G++ V +PP S +E
Sbjct: 4304 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL 4363
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G P PT+ W+ +G I + + + A++ T+N+ D D
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4416
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG LT+ S PPIIT P + + C A P+
Sbjct: 4417 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4468
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV
Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4522
Query: 487 PINPNIH 493
P+ +H
Sbjct: 4523 PVIVQVH 4529
Score = 167 bits (406), Expect = 2e-40
Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
E P DV+V + L C A G P+P I+W K G + S +T R + A G +G
Sbjct: 3251 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3308
Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ SD G Y C ATN G R N ++V + E E + ++ +EC
Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 3367
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++
Sbjct: 3368 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3425
Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
L++ P + G E++ GSS + C G P P + W R PLG
Sbjct: 3426 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3481
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
+ V G L+L D G+Y+C A N G VS L V +PP IN S ++V
Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
N TC A+G P P M W +G P D+ G VL I+ D
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3593
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
+ C A + AG + V PP I T+ P + T+ C +
Sbjct: 3594 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3648
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L
Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3708
Query: 484 VDSPINPNI 492
V+ P PNI
Sbjct: 3709 VNVP--PNI 3715
Score = 165 bits (402), Expect = 6e-40
Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423
Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
DAG Y C+A N GT++ + + ++ F P V LEC
Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 1476
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
+G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG +
Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535
Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
I L I+I P + G D+ S + +C G P+P + W + G M +
Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 1593
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
+D G L + ++D Y+C N G S ++ VY PP I NL +P + V
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+ C A G P P + W +G P + D A + +++ + D
Sbjct: 1654 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 1706
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
R +C A + AG ++ ++ V PP I G + + ++ C
Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
+P P I W +G+ + + + +G LV+ S++G Y C+A++ G +
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814
Score = 165 bits (402), Expect = 6e-40
Identities = 131/460 (28%), Positives = 211/460 (45%), Gaps = 31/460 (6%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
L+ TV P L C+A G+P P I WYK L+ T + L G + + + S
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1984
Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G T + +HVA + V LEC RG P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P++ W K+G + + L G L + A+ +D GRY C+A NAAG ++ I L+
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 2099
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
+++ P ++ ++V +V C+ P P + W + G + + + ++ S
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTC 314
L++++ + D G Y+CEA N G + + ++ PP+I S + V GN+ C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
++G P P + W +G+ ++ M R + G L I+ +K+D+ C A
Sbjct: 2219 ESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCVA 2271
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPIIA 430
N AG++ L V P ITN S+ T I KS+++ C P P +
Sbjct: 2272 SNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTVT 2325
Query: 431 WYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
W +G LI+ + ++G L LK++ SD+G Y CVA
Sbjct: 2326 WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Score = 161 bits (391), Expect = 1e-38
Identities = 142/483 (29%), Positives = 205/483 (42%), Gaps = 42/483 (8%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E P + P + + ++ C A G P P I W + +V +HR + +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G F++ DAG+Y C A+NS GT + +N+TL + + + A GD
Sbjct: 664 GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
V+EC G P P V W K L S ++D G L IQ+ + DAG Y C+A
Sbjct: 719 TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N AG R + TL + P I P DV + GS+VT C V G P P + WRR
Sbjct: 775 INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830
Query: 243 NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293
NMP+ + L G+L + N+ +D+G Y CEAEN G + + +TV P
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890
Query: 294 SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I +SP+ NV G CT G P P W I M + T DG
Sbjct: 891 LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I D C A N AG++ + V P I +G +
Sbjct: 944 --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+P + W +GE + + + + DG+L + +SG Y C A++
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 472 RHG 474
G
Sbjct: 1056 TAG 1058
Score = 160 bits (389), Expect = 2e-38
Identities = 135/481 (28%), Positives = 205/481 (42%), Gaps = 49/481 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P ++ V R + +L C G P P + W K G ++ IL G + L+ H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2355
Query: 78 SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
SD G Y C A N G T + + ++H PE+ + ++V L C G P
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2414
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W K+G + R+ L G L + DAG+Y C+ RNAAG E I L
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2472
Query: 197 KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
+ + P+++ EDV + SVT C V G+P+P++ W + +
Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309
L++ NV + G Y+C A + G S S L V+ P+I + +P V V +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592
Query: 310 ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
C A P T+ W +E NR I I PG G T+ +N +
Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2639
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415
N R + C A N AG ++ V PPII G P + + +
Sbjct: 2640 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
C A P ++WY +G+ L + N+ +G TL +K+ SD+G YTCVAS+ G
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Query: 475 K 475
+
Sbjct: 2753 E 2753
Score = 156 bits (379), Expect = 4e-37
Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV ++ A + C + GSP+P W K G ++ D H L G + + T
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2935
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
+D G Y C A N+ G+A+ + L+V V + E+ + + L C G P
Sbjct: 2936 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2993
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG + +L
Sbjct: 2994 PDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF-SL 3050
Query: 197 KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
+++ P + + V + G+SV+ +C P P + W ++ G V++L
Sbjct: 3051 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3109
Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310
DG L + ++D G+Y C A N G + +L VY PPSI V VE+ N
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC ATG P PT+ W R + + G + L I + +DS N
Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3222
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428
C A N G + L++ + PP + PS+ ++ + C A P P+
Sbjct: 3223 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
I W +G+ + + N TL + SD+G YTCVA++ G+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327
Score = 155 bits (377), Expect = 7e-37
Identities = 133/483 (27%), Positives = 202/483 (41%), Gaps = 35/483 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT AP I P V Q TL C G+P P RW K +++ + + ++ G
Sbjct: 884 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R D G Y C A+N GT ++ ++ V VL + + + +G
Sbjct: 944 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N
Sbjct: 998 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 185 AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
AG + + L ++++P + P ++ G VT C V P P + W
Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ + R L GS+++ +D G Y C A N G V+ + L V+ PP I
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
P + V+ G C A G P P + WS G+ ++ D H + DG L
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413
+I+ +D+ C A N AG+ L V +D PP T + Q
Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471
FPC A TP+P I W G L + ++ DGT LV+ + D+G Y CVA +
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Query: 472 RHG 474
G
Sbjct: 1343 EAG 1345
Score = 155 bits (377), Expect = 7e-37
Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
P I P + V Q + C A G+P P I W KGG ++V H P G L +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
AT SDAG+Y C ATN GT + TLHV LEP + Q +
Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C P +G+P+P + W NG+ L L DG LVI D G Y C+A N A
Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
GT E LK+H+ P + + +V C V G P P ++W +
Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402
Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
++ +++G L+L D G YSC+A N G + V PP+I PN
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V+V C G P P + W +G +F G + D VL + +
Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
+ND + C+ N AG KLT+ PP I G ++ ++ I S+ C
Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
P P I WY +G+ ++ + + + G L + SDS TYTC
Sbjct: 1570 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618
Score = 154 bits (373), Expect = 2e-36
Identities = 130/464 (28%), Positives = 214/464 (46%), Gaps = 37/464 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V +++P L C A G P+P+I W K V + + I +G + + T + DAG
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
Y C ATN+ G + ++ LHV E LE K + + V LEC G+P
Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
P + W K+ + L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L
Sbjct: 1950 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006
Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
++H+ P I+G ++VA + V +C G P P + W + + ++VL G
Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L L + ++D G Y+C A N+ G L VY PP+I +V+V C
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ P PT+ W +G+ + PG+S + + +VL I D D+ C A
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433
N AG + + + PP I + Q I+ ++ C + P P + W
Sbjct: 2177 TNVAGKTEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232
Query: 434 EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
+G ++ + R + + G L + +KSD+ Y+CVAS+ G
Sbjct: 2233 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 152 bits (369), Expect = 6e-36
Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)
Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3581
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + +V D G Y C A++ G + +HV EP + V
Sbjct: 3582 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3639
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N
Sbjct: 3640 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
AG + + L +++ P + GP+ +V S +C G P P + WR+ G
Sbjct: 3697 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3755
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++
Sbjct: 3756 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3813
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V C ATG P+P++ W G+ ++ +++ Y + G V+ +
Sbjct: 3814 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3866
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D T C+ N AG LTV + PP I + P++ + + AV CTA
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3921
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W G L+ + + + G + + + +G YTCVA + G
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3974
Score = 151 bits (366), Expect = 1e-35
Identities = 138/476 (28%), Positives = 204/476 (42%), Gaps = 32/476 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I V V + P L C A G P+P++ W K G V S ++ + +GG L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 2069
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
T ++ SD G Y C A N+ G + R+ L V V E ++ V L C
Sbjct: 2070 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 2125
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
P P + W K+G LL + + L I+DA+ D GRY C A N AG E
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184
Query: 191 SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL 246
+ I + P I G +++ T G+ ++ C G P P+++W++ +
Sbjct: 2185 KNY-NVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242
Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302
GRV++L G L++ +D YSC A N G L VY P+I S P +
Sbjct: 2243 GRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V G C G P PT+ W +G+ I K + D +L + +
Sbjct: 2303 IVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNIH 2354
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420
+D+ VC AVN AG + + L+V + PP II N P N ++ K+ C
Sbjct: 2355 VSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 421 AICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P I W+ +G + N R ++ L L D+G YTCV + G+
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465
Score = 149 bits (362), Expect = 5e-35
Identities = 128/454 (28%), Positives = 194/454 (42%), Gaps = 34/454 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP P I W K G L+ IL G + +V S+ G+Y C A N+
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810
Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G + T+HV + L + + V L+C+ G P P++ W K+ Q +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ G L I DAGRY C+A NAAG + I L +H P L +
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926
Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262
+ + V +C+ G+P+P + W R +G +M L R +++D +++
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1981
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P
Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W +G+ F + V G +L + +D+ C AVN AG
Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 2093
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
L V PP I N ++ I C + P P + W +G L++
Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148
Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+++ N L ++D D+G YTC A++ GK
Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 149 bits (361), Expect = 6e-35
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL +
Sbjct: 700 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+ T DAG Y C A N G A + TL V F EP G V L C
Sbjct: 760 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+G PEP + W++ +F S + + G L I + +D G Y C A N
Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873
Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
G +S T+ + P + P G +T C + G+P+P+ W + SA
Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++
Sbjct: 934 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G C A+G P+P++ WS +G S K+ A A DG + +
Sbjct: 992 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 1042
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
+ VC+A N AG + + +LTV RP +Q P++
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 1099
Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
PC P PII W E + + + R G++ + + SDSG Y CVA++ G
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 477 VWSGALLVDSP 487
+ L V P
Sbjct: 1160 TQAVKLNVHVP 1170
Score = 149 bits (361), Expect = 6e-35
Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 24/466 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV +L C + G P P + W K G V++D+ + G L+ + SDA
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2264
Query: 81 GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
+Y C A+N GTA+ N +++ P +G ++ LEC +G P P
Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2323
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
V W K+G L+ + ++D G+++ +++ +D GRY C+A N AG + L +
Sbjct: 2324 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2380
Query: 199 HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
H P +I PE++ +SV+ C G PLP + W + ++ V++L G
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGG 2439
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
LRL + D G+Y+C N+ G L+V PP I + V V+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2499
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
TC TG P P + W +G P + +H + G L I + + C
Sbjct: 2500 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2550
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A + AG L V P + T+ + S C A P I W+
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610
Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477
+G L N + G TL + + + ++G Y+CVA++ G+ +
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656
Score = 147 bits (355), Expect = 3e-34
Identities = 138/533 (25%), Positives = 230/533 (43%), Gaps = 34/533 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P +I+ P +VTV + A L C + + W + V +++ R A
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127
L++ +DAG Y C ++ G++ A++ + V + + P+++ G V +
Sbjct: 578 LKSVK---FNDAGEYHCMVSSEGGSSA---ASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P+P + W N ++ G R + G L I++A DAG Y C+A N+AG
Sbjct: 632 MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T + +TL+ P L+ +++ G +C+ G P P V W + G +
Sbjct: 689 T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745
Query: 248 RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++D G L++ D G+Y+C A N G + L V PP P V++E
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362
G+ C G PEPT+ W N I F S + A+F +L + +D
Sbjct: 806 IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K T +C A N G ++ + TVT P+I PS + PCT +
Sbjct: 862 K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914
Query: 423 C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W L+QN V +DG+L ++ + D G YTCVAS+ G + +
Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
++V + P I + +S++ G P + ++ WS+ ++ S+S
Sbjct: 975 VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024
Score = 140 bits (339), Expect = 3e-32
Identities = 126/466 (27%), Positives = 185/466 (39%), Gaps = 31/466 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V +L C + P P I WYK G ++ TH IL G + ++ SD
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3125
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N G +N L+V V E E + V L C G P P +
Sbjct: 3126 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3183
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3242
Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
+ P + P DV G +V C G P P + W + + R++V +GS
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
L + + +D G+Y+C A N G L VY P+I + + V
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C ATG P P + W G + P S + A + ++D C
Sbjct: 3363 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3413
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
A N AG L V + PP + N + + + S C TP P +A
Sbjct: 3414 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W +G+ L + H T+ L L + DSG YTC+AS+ G+
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514
Score = 128 bits (309), Expect = 1e-28
Identities = 128/486 (26%), Positives = 195/486 (40%), Gaps = 50/486 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +++V +L C A G P P+I W+K G V IL G + L T
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT---TM 2449
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRG 134
DAG Y C N+ G R + L V V + E LE + Q T+ E G
Sbjct: 2450 EDAGQYTCVVRNAAGEER-KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT---G 2505
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAI 193
+P P + W K+GQ L D H++ GG L I + + GRY C+A + AG + +
Sbjct: 2506 NPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 194 ATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ L + + P + PEDV S + C P + W + G + R
Sbjct: 2564 S-LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKD--GTPLESNR 2620
Query: 249 -VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--------LS 298
+++L G +L++ N + G YSC A N G + + VY PP IN LS
Sbjct: 2621 NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P V ++ N C A P ++ W +G P S D H +G T L I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ-----PLKSDD--HVNIAANGHT-LQI 2732
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--------PIITNGPSNQTLP 410
+ +D+ C A N AG + + + NG + +
Sbjct: 2733 KEAQISDT-GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
++++ C P P + WY +G L + + + G L + D+G YTCVA
Sbjct: 2792 NNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVA 2850
Query: 470 SSRHGK 475
+ G+
Sbjct: 2851 VNEAGE 2856
Score = 126 bits (304), Expect = 5e-28
Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%)
Query: 12 PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P+I+ E L DV V Q TL C G+P P I W+K G + D I+ G FL
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2535
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125
+ T+ +V G Y C A++ G +SR+ +L+V V + PE
Sbjct: 2536 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C P + W K+G L + + R+ L G L I +A++ +AGRY C+A N
Sbjct: 2594 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2651
Query: 186 AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
AG +K++I P + G P++V + +++T +C P + W +
Sbjct: 2652 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710
Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295
G V + +G +L++ ++D G Y+C A N G + + PPS
Sbjct: 2711 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2769
Query: 296 ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
N+ N E+ N C P PT+ W +G+ P S DK
Sbjct: 2770 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2823
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403
+ G VL I D+ C AVN AG ++ + V PPII
Sbjct: 2824 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIKGAN 2875
Query: 404 ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459
P T+ + A+ C + +P P +W +G+ L++ +H + ++N L + +
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 460 SDSGTYTCVASSRHG 474
+D G Y CVA + G
Sbjct: 2936 TDIGRYVCVAENTAG 2950
Score = 123 bits (296), Expect = 4e-27
Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
SD G Y C A +S GT R++ V+ ++ P + G+ VL CL + +
Sbjct: 492 SDEGFYECIAVSSAGTGRAQ-TFFDVSEPPPVIQV-PNNVTVTPGERAVLTCL-IISAVD 548
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
N+ W++N + + +R+ + +L ++ + DAG Y C+ + G+ +A L
Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+ P + P++ GS V+ C G P P + W + + R ++ DG+L
Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ N D G Y C A NS G + L + P + + + + V G++ C +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376
G P P + W F G + + D + +L I +T D+ C A+N
Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + GK+T+ D PP+ P++ ++ I S PC PEP I W
Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831
Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
I + +V++ G L + +L SD GTY C A ++ GK + V + P
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891
Query: 492 I 492
I
Sbjct: 892 I 892
Score = 103 bits (246), Expect = 5e-21
Identities = 88/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%)
Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
NL I +D G Y+CIA ++AGT A + P +I P +V G C
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC 541
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
+ ++ W+R+ + R++ L + SL L +V D GEY C + G+ +
Sbjct: 542 LIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSA 601
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
AS +LTV +PP + + P + + G+ C+ATG P+P + W+V N I +
Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTV--NDMFI---VGSH 656
Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
+Y T+ DG L I + D+ C A N AG+ L + P ++
Sbjct: 657 RYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGTDKQNSTLRYI---EAPKLMVVQ 708
Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLKDLDKS 460
S + + + V C P P + W F+G+ ++ + + G L +++
Sbjct: 709 --SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDL 765
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G YTCVA + G+ L V SP
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I +P++ + LNC+A G P P I W + G + D ++L
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4493
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
L+ A D + C A N G+ R
Sbjct: 4494 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4521
>AL121996-1|CAI17844.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-118G19 on chromosome 1q25.1-31.1. ).
Length = 5635
Score = 206 bits (502), Expect = 5e-52
Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4045
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126
RA V DAG Y C A N GTA + L+V V + P K+ A +
Sbjct: 4046 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4097
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A
Sbjct: 4098 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ S L +H+ P + + S C G P P + W++ L
Sbjct: 4155 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++
Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R +C ATG P P + W+ N I P H +V +G + L I K DS
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4323
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
T VC+A N G G + V PP + PSN P+ A+ C P
Sbjct: 4324 -GTYVCTAENSVGFVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 487 P 487
P
Sbjct: 4439 P 4439
Score = 187 bits (456), Expect = 2e-46
Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3955
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C
Sbjct: 3956 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4009
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT
Sbjct: 4010 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4067
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
I L + + P + ++ V +T C G P PD+ W + G + R
Sbjct: 4068 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4125
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
+VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V +
Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P P + W + ++ + KY A + L + + DS
Sbjct: 4186 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4236
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG LTV P T P + +L C A P P +
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
W F +I H +V LV++ + K DSGTY C A + G G + V P
Sbjct: 4292 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348
Score = 186 bits (452), Expect = 6e-46
Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I P + + ++ L C A G P+P I W K G ++ + R + G
Sbjct: 3707 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3766
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+++ H +D G Y C ATN+ GT R R L V V P +
Sbjct: 3767 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3821
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N
Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG + + L + + P + P D + + C G P P + W ++ G +
Sbjct: 3881 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3938
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++
Sbjct: 3939 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3998
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V N C ATG P P + W EG + + HA G L I+ +
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4050
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T +C A N AG++ + KL V + PP+I+ + + C A
Sbjct: 4051 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4104
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L
Sbjct: 4105 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
V P P I R+ + ++ I V D T ++W ++N + ++ + Y E
Sbjct: 4165 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4219
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
+ E + N +S + +A TH V
Sbjct: 4220 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Score = 182 bits (442), Expect = 9e-45
Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
G P I++P DV++ TL C G P P I+W + + + S + S L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G LF L SD G Y CEA N +G +S ++ + P +G
Sbjct: 850 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
+ L C G+P P W KN LL + + + G+L I+ + D G Y C+A
Sbjct: 906 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
N AGT + + +H+ P + G + + G VT C+ G+P P V+W + +
Sbjct: 964 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
+ DGSL + + + GEY C A N+ G LTVY P + LS
Sbjct: 1023 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 1082
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
P ++V +G C P P + W+ E +I P R + +
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I +T +DS +C A N AG+ KL V PP I GP + + +
Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474
PC A TP P+I W G ++ + +V+N DGTL + SD+G YTCVA++ G
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Score = 177 bits (431), Expect = 2e-43
Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G DAG Y C A N G++ S T+HV R + +L
Sbjct: 4136 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4188
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG
Sbjct: 4189 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
++ +L +H+ P P DV G + C+ G PLP + W + +P
Sbjct: 4247 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4303
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V L ++ V D G Y C AENSVG V A G++ V +PP S +E
Sbjct: 4304 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL 4363
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G P PT+ W+ +G I + + + A++ T+N+ D D
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4416
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG LT+ S PPIIT P + + C A P+
Sbjct: 4417 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4468
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV
Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4522
Query: 487 PINPNIH 493
P+ +H
Sbjct: 4523 PVIVQVH 4529
Score = 167 bits (406), Expect = 2e-40
Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
E P DV+V + L C A G P+P I+W K G + S +T R + A G +G
Sbjct: 3251 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3308
Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ SD G Y C ATN G R N ++V + E E + ++ +EC
Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 3367
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++
Sbjct: 3368 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3425
Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
L++ P + G E++ GSS + C G P P + W R PLG
Sbjct: 3426 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3481
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
+ V G L+L D G+Y+C A N G VS L V +PP IN S ++V
Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
N TC A+G P P M W +G P D+ G VL I+ D
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3593
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
+ C A + AG + V PP I T+ P + T+ C +
Sbjct: 3594 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3648
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L
Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3708
Query: 484 VDSPINPNI 492
V+ P PNI
Sbjct: 3709 VNVP--PNI 3715
Score = 165 bits (402), Expect = 6e-40
Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423
Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
DAG Y C+A N GT++ + + ++ F P V LEC
Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 1476
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
+G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG +
Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535
Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
I L I+I P + G D+ S + +C G P+P + W + G M +
Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 1593
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
+D G L + ++D Y+C N G S ++ VY PP I NL +P + V
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+ C A G P P + W +G P + D A + +++ + D
Sbjct: 1654 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 1706
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
R +C A + AG ++ ++ V PP I G + + ++ C
Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
+P P I W +G+ + + + +G LV+ S++G Y C+A++ G +
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814
Score = 165 bits (402), Expect = 6e-40
Identities = 131/460 (28%), Positives = 211/460 (45%), Gaps = 31/460 (6%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
L+ TV P L C+A G+P P I WYK L+ T + L G + + + S
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1984
Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G T + +HVA + V LEC RG P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P++ W K+G + + L G L + A+ +D GRY C+A NAAG ++ I L+
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 2099
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
+++ P ++ ++V +V C+ P P + W + G + + + ++ S
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTC 314
L++++ + D G Y+CEA N G + + ++ PP+I S + V GN+ C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
++G P P + W +G+ ++ M R + G L I+ +K+D+ C A
Sbjct: 2219 ESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCVA 2271
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPIIA 430
N AG++ L V P ITN S+ T I KS+++ C P P +
Sbjct: 2272 SNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTVT 2325
Query: 431 WYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
W +G LI+ + ++G L LK++ SD+G Y CVA
Sbjct: 2326 WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Score = 161 bits (391), Expect = 1e-38
Identities = 142/483 (29%), Positives = 205/483 (42%), Gaps = 42/483 (8%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E P + P + + ++ C A G P P I W + +V +HR + +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G F++ DAG+Y C A+NS GT + +N+TL + + + A GD
Sbjct: 664 GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
V+EC G P P V W K L S ++D G L IQ+ + DAG Y C+A
Sbjct: 719 TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N AG R + TL + P I P DV + GS+VT C V G P P + WRR
Sbjct: 775 INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830
Query: 243 NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293
NMP+ + L G+L + N+ +D+G Y CEAEN G + + +TV P
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890
Query: 294 SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I +SP+ NV G CT G P P W I M + T DG
Sbjct: 891 LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I D C A N AG++ + V P I +G +
Sbjct: 944 --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+P + W +GE + + + + DG+L + +SG Y C A++
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 472 RHG 474
G
Sbjct: 1056 TAG 1058
Score = 160 bits (389), Expect = 2e-38
Identities = 135/481 (28%), Positives = 205/481 (42%), Gaps = 49/481 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P ++ V R + +L C G P P + W K G ++ IL G + L+ H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2355
Query: 78 SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
SD G Y C A N G T + + ++H PE+ + ++V L C G P
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2414
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W K+G + R+ L G L + DAG+Y C+ RNAAG E I L
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2472
Query: 197 KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
+ + P+++ EDV + SVT C V G+P+P++ W + +
Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309
L++ NV + G Y+C A + G S S L V+ P+I + +P V V +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592
Query: 310 ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
C A P T+ W +E NR I I PG G T+ +N +
Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2639
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415
N R + C A N AG ++ V PPII G P + + +
Sbjct: 2640 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
C A P ++WY +G+ L + N+ +G TL +K+ SD+G YTCVAS+ G
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Query: 475 K 475
+
Sbjct: 2753 E 2753
Score = 156 bits (379), Expect = 4e-37
Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV ++ A + C + GSP+P W K G ++ D H L G + + T
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2935
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
+D G Y C A N+ G+A+ + L+V V + E+ + + L C G P
Sbjct: 2936 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2993
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG + +L
Sbjct: 2994 PDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF-SL 3050
Query: 197 KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
+++ P + + V + G+SV+ +C P P + W ++ G V++L
Sbjct: 3051 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3109
Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310
DG L + ++D G+Y C A N G + +L VY PPSI V VE+ N
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC ATG P PT+ W R + + G + L I + +DS N
Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3222
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428
C A N G + L++ + PP + PS+ ++ + C A P P+
Sbjct: 3223 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
I W +G+ + + N TL + SD+G YTCVA++ G+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327
Score = 155 bits (377), Expect = 7e-37
Identities = 133/483 (27%), Positives = 202/483 (41%), Gaps = 35/483 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT AP I P V Q TL C G+P P RW K +++ + + ++ G
Sbjct: 884 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R D G Y C A+N GT ++ ++ V VL + + + +G
Sbjct: 944 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N
Sbjct: 998 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 185 AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
AG + + L ++++P + P ++ G VT C V P P + W
Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ + R L GS+++ +D G Y C A N G V+ + L V+ PP I
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
P + V+ G C A G P P + WS G+ ++ D H + DG L
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413
+I+ +D+ C A N AG+ L V +D PP T + Q
Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471
FPC A TP+P I W G L + ++ DGT LV+ + D+G Y CVA +
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Query: 472 RHG 474
G
Sbjct: 1343 EAG 1345
Score = 155 bits (377), Expect = 7e-37
Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
P I P + V Q + C A G+P P I W KGG ++V H P G L +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
AT SDAG+Y C ATN GT + TLHV LEP + Q +
Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C P +G+P+P + W NG+ L L DG LVI D G Y C+A N A
Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
GT E LK+H+ P + + +V C V G P P ++W +
Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402
Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
++ +++G L+L D G YSC+A N G + V PP+I PN
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V+V C G P P + W +G +F G + D VL + +
Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
+ND + C+ N AG KLT+ PP I G ++ ++ I S+ C
Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
P P I WY +G+ ++ + + + G L + SDS TYTC
Sbjct: 1570 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618
Score = 154 bits (373), Expect = 2e-36
Identities = 130/464 (28%), Positives = 214/464 (46%), Gaps = 37/464 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V +++P L C A G P+P+I W K V + + I +G + + T + DAG
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
Y C ATN+ G + ++ LHV E LE K + + V LEC G+P
Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
P + W K+ + L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L
Sbjct: 1950 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006
Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
++H+ P I+G ++VA + V +C G P P + W + + ++VL G
Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L L + ++D G Y+C A N+ G L VY PP+I +V+V C
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ P PT+ W +G+ + PG+S + + +VL I D D+ C A
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433
N AG + + + PP I + Q I+ ++ C + P P + W
Sbjct: 2177 TNVAGKTEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232
Query: 434 EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
+G ++ + R + + G L + +KSD+ Y+CVAS+ G
Sbjct: 2233 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 152 bits (369), Expect = 6e-36
Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)
Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3581
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + +V D G Y C A++ G + +HV EP + V
Sbjct: 3582 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3639
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N
Sbjct: 3640 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
AG + + L +++ P + GP+ +V S +C G P P + WR+ G
Sbjct: 3697 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3755
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++
Sbjct: 3756 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3813
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V C ATG P+P++ W G+ ++ +++ Y + G V+ +
Sbjct: 3814 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3866
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D T C+ N AG LTV + PP I + P++ + + AV CTA
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3921
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W G L+ + + + G + + + +G YTCVA + G
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3974
Score = 151 bits (366), Expect = 1e-35
Identities = 138/476 (28%), Positives = 204/476 (42%), Gaps = 32/476 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I V V + P L C A G P+P++ W K G V S ++ + +GG L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 2069
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
T ++ SD G Y C A N+ G + R+ L V V E ++ V L C
Sbjct: 2070 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 2125
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
P P + W K+G LL + + L I+DA+ D GRY C A N AG E
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184
Query: 191 SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL 246
+ I + P I G +++ T G+ ++ C G P P+++W++ +
Sbjct: 2185 KNY-NVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242
Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302
GRV++L G L++ +D YSC A N G L VY P+I S P +
Sbjct: 2243 GRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V G C G P PT+ W +G+ I K + D +L + +
Sbjct: 2303 IVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNIH 2354
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420
+D+ VC AVN AG + + L+V + PP II N P N ++ K+ C
Sbjct: 2355 VSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 421 AICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P I W+ +G + N R ++ L L D+G YTCV + G+
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465
Score = 149 bits (362), Expect = 5e-35
Identities = 128/454 (28%), Positives = 194/454 (42%), Gaps = 34/454 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP P I W K G L+ IL G + +V S+ G+Y C A N+
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810
Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G + T+HV + L + + V L+C+ G P P++ W K+ Q +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ G L I DAGRY C+A NAAG + I L +H P L +
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926
Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262
+ + V +C+ G+P+P + W R +G +M L R +++D +++
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1981
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P
Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W +G+ F + V G +L + +D+ C AVN AG
Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 2093
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
L V PP I N ++ I C + P P + W +G L++
Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148
Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+++ N L ++D D+G YTC A++ GK
Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 149 bits (361), Expect = 6e-35
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL +
Sbjct: 700 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+ T DAG Y C A N G A + TL V F EP G V L C
Sbjct: 760 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+G PEP + W++ +F S + + G L I + +D G Y C A N
Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873
Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
G +S T+ + P + P G +T C + G+P+P+ W + SA
Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++
Sbjct: 934 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G C A+G P+P++ WS +G S K+ A A DG + +
Sbjct: 992 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 1042
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
+ VC+A N AG + + +LTV RP +Q P++
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 1099
Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
PC P PII W E + + + R G++ + + SDSG Y CVA++ G
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 477 VWSGALLVDSP 487
+ L V P
Sbjct: 1160 TQAVKLNVHVP 1170
Score = 149 bits (361), Expect = 6e-35
Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 24/466 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV +L C + G P P + W K G V++D+ + G L+ + SDA
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2264
Query: 81 GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
+Y C A+N GTA+ N +++ P +G ++ LEC +G P P
Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2323
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
V W K+G L+ + ++D G+++ +++ +D GRY C+A N AG + L +
Sbjct: 2324 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2380
Query: 199 HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
H P +I PE++ +SV+ C G PLP + W + ++ V++L G
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGG 2439
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
LRL + D G+Y+C N+ G L+V PP I + V V+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2499
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
TC TG P P + W +G P + +H + G L I + + C
Sbjct: 2500 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2550
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A + AG L V P + T+ + S C A P I W+
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610
Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477
+G L N + G TL + + + ++G Y+CVA++ G+ +
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656
Score = 147 bits (355), Expect = 3e-34
Identities = 138/533 (25%), Positives = 230/533 (43%), Gaps = 34/533 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P +I+ P +VTV + A L C + + W + V +++ R A
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127
L++ +DAG Y C ++ G++ A++ + V + + P+++ G V +
Sbjct: 578 LKSVK---FNDAGEYHCMVSSEGGSSA---ASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P+P + W N ++ G R + G L I++A DAG Y C+A N+AG
Sbjct: 632 MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T + +TL+ P L+ +++ G +C+ G P P V W + G +
Sbjct: 689 T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745
Query: 248 RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++D G L++ D G+Y+C A N G + L V PP P V++E
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362
G+ C G PEPT+ W N I F S + A+F +L + +D
Sbjct: 806 IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K T +C A N G ++ + TVT P+I PS + PCT +
Sbjct: 862 K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914
Query: 423 C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W L+QN V +DG+L ++ + D G YTCVAS+ G + +
Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
++V + P I + +S++ G P + ++ WS+ ++ S+S
Sbjct: 975 VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024
Score = 140 bits (339), Expect = 3e-32
Identities = 126/466 (27%), Positives = 185/466 (39%), Gaps = 31/466 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V +L C + P P I WYK G ++ TH IL G + ++ SD
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3125
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N G +N L+V V E E + V L C G P P +
Sbjct: 3126 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3183
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3242
Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
+ P + P DV G +V C G P P + W + + R++V +GS
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
L + + +D G+Y+C A N G L VY P+I + + V
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C ATG P P + W G + P S + A + ++D C
Sbjct: 3363 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3413
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
A N AG L V + PP + N + + + S C TP P +A
Sbjct: 3414 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W +G+ L + H T+ L L + DSG YTC+AS+ G+
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514
Score = 128 bits (309), Expect = 1e-28
Identities = 128/486 (26%), Positives = 195/486 (40%), Gaps = 50/486 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +++V +L C A G P P+I W+K G V IL G + L T
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT---TM 2449
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRG 134
DAG Y C N+ G R + L V V + E LE + Q T+ E G
Sbjct: 2450 EDAGQYTCVVRNAAGEER-KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT---G 2505
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAI 193
+P P + W K+GQ L D H++ GG L I + + GRY C+A + AG + +
Sbjct: 2506 NPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 194 ATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ L + + P + PEDV S + C P + W + G + R
Sbjct: 2564 S-LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKD--GTPLESNR 2620
Query: 249 -VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--------LS 298
+++L G +L++ N + G YSC A N G + + VY PP IN LS
Sbjct: 2621 NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P V ++ N C A P ++ W +G P S D H +G T L I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ-----PLKSDD--HVNIAANGHT-LQI 2732
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--------PIITNGPSNQTLP 410
+ +D+ C A N AG + + + NG + +
Sbjct: 2733 KEAQISDT-GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
++++ C P P + WY +G L + + + G L + D+G YTCVA
Sbjct: 2792 NNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVA 2850
Query: 470 SSRHGK 475
+ G+
Sbjct: 2851 VNEAGE 2856
Score = 126 bits (304), Expect = 5e-28
Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%)
Query: 12 PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P+I+ E L DV V Q TL C G+P P I W+K G + D I+ G FL
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2535
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125
+ T+ +V G Y C A++ G +SR+ +L+V V + PE
Sbjct: 2536 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C P + W K+G L + + R+ L G L I +A++ +AGRY C+A N
Sbjct: 2594 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2651
Query: 186 AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
AG +K++I P + G P++V + +++T +C P + W +
Sbjct: 2652 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710
Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295
G V + +G +L++ ++D G Y+C A N G + + PPS
Sbjct: 2711 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2769
Query: 296 ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
N+ N E+ N C P PT+ W +G+ P S DK
Sbjct: 2770 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2823
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403
+ G VL I D+ C AVN AG ++ + V PPII
Sbjct: 2824 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIKGAN 2875
Query: 404 ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459
P T+ + A+ C + +P P +W +G+ L++ +H + ++N L + +
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 460 SDSGTYTCVASSRHG 474
+D G Y CVA + G
Sbjct: 2936 TDIGRYVCVAENTAG 2950
Score = 123 bits (296), Expect = 4e-27
Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
SD G Y C A +S GT R++ V+ ++ P + G+ VL CL + +
Sbjct: 492 SDEGFYECIAVSSAGTGRAQ-TFFDVSEPPPVIQV-PNNVTVTPGERAVLTCL-IISAVD 548
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
N+ W++N + + +R+ + +L ++ + DAG Y C+ + G+ +A L
Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+ P + P++ GS V+ C G P P + W + + R ++ DG+L
Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ N D G Y C A NS G + L + P + + + + V G++ C +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376
G P P + W F G + + D + +L I +T D+ C A+N
Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + GK+T+ D PP+ P++ ++ I S PC PEP I W
Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831
Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
I + +V++ G L + +L SD GTY C A ++ GK + V + P
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891
Query: 492 I 492
I
Sbjct: 892 I 892
Score = 103 bits (246), Expect = 5e-21
Identities = 88/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%)
Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
NL I +D G Y+CIA ++AGT A + P +I P +V G C
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC 541
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
+ ++ W+R+ + R++ L + SL L +V D GEY C + G+ +
Sbjct: 542 LIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSA 601
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
AS +LTV +PP + + P + + G+ C+ATG P+P + W+V N I +
Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTV--NDMFI---VGSH 656
Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
+Y T+ DG L I + D+ C A N AG+ L + P ++
Sbjct: 657 RYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGTDKQNSTLRYI---EAPKLMVVQ 708
Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLKDLDKS 460
S + + + V C P P + W F+G+ ++ + + G L +++
Sbjct: 709 --SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDL 765
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G YTCVA + G+ L V SP
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I +P++ + LNC+A G P P I W + G + D ++L
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4493
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
L+ A D + C A N G+ R
Sbjct: 4494 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4521
>AL118512-1|CAI17864.1| 5635|Homo sapiens protein ( Human DNA sequence
from clone GS1-248A21 on chromosome 1q31.1-31.3. ).
Length = 5635
Score = 206 bits (502), Expect = 5e-52
Identities = 153/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL
Sbjct: 3986 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 4045
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVV 126
RA V DAG Y C A N GTA + L+V V + P K+ A +
Sbjct: 4046 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 4097
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A
Sbjct: 4098 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVA 4154
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ S L +H+ P + + S C G P P + W++ L
Sbjct: 4155 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 4213
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++
Sbjct: 4214 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 4273
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R +C ATG P P + W+ N I P H +V +G + L I K DS
Sbjct: 4274 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 4323
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
T VC+A N G G + V PP + PSN P+ A+ C P
Sbjct: 4324 -GTYVCTAENSVGFVKAIGFVYVKE----PPVFKGDYPSNWIEPLGGNAILNCEVKGDPT 4378
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S
Sbjct: 4379 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 4438
Query: 487 P 487
P
Sbjct: 4439 P 4439
Score = 187 bits (456), Expect = 2e-46
Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L
Sbjct: 3897 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 3955
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C
Sbjct: 3956 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 4009
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT
Sbjct: 4010 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 4067
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
I L + + P + ++ V +T C G P PD+ W + G + R
Sbjct: 4068 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 4125
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
+VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V +
Sbjct: 4126 RVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 4185
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P P + W + ++ + KY A + L + + DS
Sbjct: 4186 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 4236
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG LTV P T P + +L C A P P +
Sbjct: 4237 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 4291
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
W F +I H +V LV++ + K DSGTY C A + G G + V P
Sbjct: 4292 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 4348
Score = 186 bits (452), Expect = 6e-46
Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I P + + ++ L C A G P+P I W K G ++ + R + G
Sbjct: 3707 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 3766
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+++ H +D G Y C ATN+ GT R R L V V P +
Sbjct: 3767 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 3821
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N
Sbjct: 3822 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 3880
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG + + L + + P + P D + + C G P P + W ++ G +
Sbjct: 3881 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 3938
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++
Sbjct: 3939 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 3998
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V N C ATG P P + W EG + + HA G L I+ +
Sbjct: 3999 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 4050
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T +C A N AG++ + KL V + PP+I+ + + C A
Sbjct: 4051 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 4104
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L
Sbjct: 4105 LPPPDITWHKDGRAIVESIRQRVLSSGSLQIAFVQPGDAGHYTCMAANVAGSSSTSTKLT 4164
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
V P P I R+ + ++ I V D T ++W ++N + ++ + Y E
Sbjct: 4165 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 4219
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
+ E + N +S + +A TH V
Sbjct: 4220 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 4252
Score = 182 bits (442), Expect = 9e-45
Identities = 137/480 (28%), Positives = 205/480 (42%), Gaps = 35/480 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
G P I++P DV++ TL C G P P I+W + + + S + S L
Sbjct: 790 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 849
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G LF L SD G Y CEA N +G +S ++ + P +G
Sbjct: 850 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 905
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
+ L C G+P P W KN LL + + + G+L I+ + D G Y C+A
Sbjct: 906 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 963
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
N AGT + + +H+ P + G + + G VT C+ G+P P V+W + +
Sbjct: 964 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 1022
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
+ DGSL + + + GEY C A N+ G LTVY P + LS
Sbjct: 1023 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 1082
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
P ++V +G C P P + W+ E +I P R + +
Sbjct: 1083 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 1134
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I +T +DS +C A N AG+ KL V PP I GP + + +
Sbjct: 1135 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV-----HVPPKIQRGPKHLKVQVGQRV 1188
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLVLKDLDKSDSGTYTCVASSRHG 474
PC A TP P+I W G ++ + +V+N DGTL + SD+G YTCVA++ G
Sbjct: 1189 DIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQATPSDAGIYTCVATNIAG 1248
Score = 177 bits (431), Expect = 2e-43
Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G DAG Y C A N G++ S T+HV R + +L
Sbjct: 4136 AFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 4188
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG
Sbjct: 4189 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 4246
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
++ +L +H+ P P DV G + C+ G PLP + W + +P
Sbjct: 4247 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 4303
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V L ++ V D G Y C AENSVG V A G++ V +PP S +E
Sbjct: 4304 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPL 4363
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G P PT+ W+ +G I + + + A++ T+N+ D D
Sbjct: 4364 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 4416
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG LT+ S PPIIT P + + C A P+
Sbjct: 4417 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 4468
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV
Sbjct: 4469 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 4522
Query: 487 PINPNIH 493
P+ +H
Sbjct: 4523 PVIVQVH 4529
Score = 167 bits (406), Expect = 2e-40
Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
E P DV+V + L C A G P+P I+W K G + S +T R + A G +G
Sbjct: 3251 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 3308
Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ SD G Y C ATN G R N ++V + E E + ++ +EC
Sbjct: 3309 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 3367
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++
Sbjct: 3368 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 3425
Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
L++ P + G E++ GSS + C G P P + W R PLG
Sbjct: 3426 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 3481
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
+ V G L+L D G+Y+C A N G VS L V +PP IN S ++V
Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
N TC A+G P P M W +G P D+ G VL I+ D
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 3593
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
+ C A + AG + V PP I T+ P + T+ C +
Sbjct: 3594 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 3648
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L
Sbjct: 3649 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 3708
Query: 484 VDSPINPNI 492
V+ P PNI
Sbjct: 3709 VNVP--PNI 3715
Score = 165 bits (402), Expect = 6e-40
Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATP- 1423
Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
DAG Y C+A N GT++ + + ++ F P V LEC
Sbjct: 1424 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 1476
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
+G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG +
Sbjct: 1477 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 1535
Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
I L I+I P + G D+ S + +C G P+P + W + G M +
Sbjct: 1536 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 1593
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
+D G L + ++D Y+C N G S ++ VY PP I NL +P + V
Sbjct: 1594 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 1653
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+ C A G P P + W +G P + D A + +++ + D
Sbjct: 1654 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 1706
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
R +C A + AG ++ ++ V PP I G + + ++ C
Sbjct: 1707 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 1759
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
+P P I W +G+ + + + +G LV+ S++G Y C+A++ G +
Sbjct: 1760 GSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 1814
Score = 165 bits (402), Expect = 6e-40
Identities = 131/460 (28%), Positives = 211/460 (45%), Gaps = 31/460 (6%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
L+ TV P L C+A G+P P I WYK L+ T + L G + + + S
Sbjct: 1928 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1984
Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G T + +HVA + V LEC RG P
Sbjct: 1985 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 2040
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P++ W K+G + + L G L + A+ +D GRY C+A NAAG ++ I L+
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 2099
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
+++ P ++ ++V +V C+ P P + W + G + + + ++ S
Sbjct: 2100 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 2158
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTC 314
L++++ + D G Y+CEA N G + + ++ PP+I S + V GN+ C
Sbjct: 2159 LKIEDAQVQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSDELTQLTVIEGNLISLLC 2218
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
++G P P + W +G+ ++ M R + G L I+ +K+D+ C A
Sbjct: 2219 ESSGIPPPNLIWKKKGS-PVLTDSMGR-----VRILSGGRQLQISIAEKSDAA-LYSCVA 2271
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI----KSMAVFPCTAICTPEPIIA 430
N AG++ L V P ITN S+ T I KS+++ C P P +
Sbjct: 2272 SNVAGTAKKEYNLQVYI-----RPTITNSGSHPTEIIVTRGKSISL-ECEVQGIPPPTVT 2325
Query: 431 WYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
W +G LI+ + ++G L LK++ SD+G Y CVA
Sbjct: 2326 WMKDGHPLIKAKGVEILDEGHILQLKNIHVSDTGRYVCVA 2365
Score = 161 bits (391), Expect = 1e-38
Identities = 142/483 (29%), Positives = 205/483 (42%), Gaps = 42/483 (8%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E P + P + + ++ C A G P P I W + +V +HR + +
Sbjct: 605 FLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVG-SHRYRMTSD 663
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G F++ DAG+Y C A+NS GT + +N+TL + + + A GD
Sbjct: 664 GTLFIK---NAAPKDAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDI 718
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIA 182
V+EC G P P V W K L S ++D G L IQ+ + DAG Y C+A
Sbjct: 719 TVMEC-KTSGIPPPQVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVA 774
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N AG R + TL + P I P DV + GS+VT C V G P P + WRR
Sbjct: 775 INEAG-RATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---D 830
Query: 243 NMPL-------GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PP 293
NMP+ + L G+L + N+ +D+G Y CEAEN G + + +TV P
Sbjct: 831 NMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAP 890
Query: 294 SINLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I +SP+ NV G CT G P P W I M + T DG
Sbjct: 891 LIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG 943
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I D C A N AG++ + V P I +G +
Sbjct: 944 --SLHIERVQLQDG-GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEG 995
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+P + W +GE + + + + DG+L + +SG Y C A++
Sbjct: 996 IPVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 472 RHG 474
G
Sbjct: 1056 TAG 1058
Score = 160 bits (389), Expect = 2e-38
Identities = 135/481 (28%), Positives = 205/481 (42%), Gaps = 49/481 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P ++ V R + +L C G P P + W K G ++ IL G + L+ H
Sbjct: 2299 PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVEILDEGHILQLKNIH---V 2355
Query: 78 SDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
SD G Y C A N G T + + ++H PE+ + ++V L C G P
Sbjct: 2356 SDTGRYVCVAVNVAGMTDKKYDLSVHAPPSIIGNHRSPENISVVEKNSVSLTC-EASGIP 2414
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W K+G + R+ L G L + DAG+Y C+ RNAAG E I L
Sbjct: 2415 LPSITWFKDGWPVSLSNSVRI-LSGGRMLRLMQTTMEDAGQYTCVVRNAAG-EERKIFGL 2472
Query: 197 KIHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
+ + P+++ EDV + SVT C V G+P+P++ W + +
Sbjct: 2473 SVLVPPHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGG 2532
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLSPNSVNVESGNV 309
L++ NV + G Y+C A + G S S L V+ P+I + +P V V +
Sbjct: 2533 RFLQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSP 2592
Query: 310 ARFTCTATGRPEPTMFW-----SVEGNRTI-IFPGMSRDKYHATAVFDGVTVLTINDTDK 363
C A P T+ W +E NR I I PG G T+ +N +
Sbjct: 2593 TSLVCEAYSYPPATITWFKDGTPLESNRNIRILPG-------------GRTLQILNAQED 2639
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--------PSNQTLPIKSMA 415
N R + C A N AG ++ V PPII G P + + +
Sbjct: 2640 NAGRYS--CVATNEAGEMIKHYEVKVYI-----PPIINKGDLWGPGLSPKEVKIKVNNTL 2692
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
C A P ++WY +G+ L + N+ +G TL +K+ SD+G YTCVAS+ G
Sbjct: 2693 TLECEAYAIPSASLSWYKDGQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAG 2752
Query: 475 K 475
+
Sbjct: 2753 E 2753
Score = 156 bits (379), Expect = 4e-37
Identities = 132/470 (28%), Positives = 209/470 (44%), Gaps = 33/470 (7%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV ++ A + C + GSP+P W K G ++ D H L G + + T
Sbjct: 2879 PEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQ---I 2935
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
+D G Y C A N+ G+A+ + L+V V + E+ + + L C G P
Sbjct: 2936 TDIGRYVCVAENTAGSAK-KYFNLNVHVPPSVIGPKSENLTVVVNNFISLTC-EVSGFPP 2993
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG + +L
Sbjct: 2994 PDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKF-SL 3050
Query: 197 KIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
+++ P + + V + G+SV+ +C P P + W ++ G V++L
Sbjct: 3051 TVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPPPVITWYKN-GRMITESTHVEIL 3109
Query: 253 DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES-GNVA 310
DG L + ++D G+Y C A N G + +L VY PPSI V VE+ N
Sbjct: 3110 ADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETISNPV 3169
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC ATG P PT+ W R + + G + L I + +DS N
Sbjct: 3170 TLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDSGN-Y 3222
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICTPEPI 428
C A N G + L++ + PP + PS+ ++ + C A P P+
Sbjct: 3223 TCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPL 3277
Query: 429 IAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
I W +G+ + + N TL + SD+G YTCVA++ G+
Sbjct: 3278 IQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 3327
Score = 155 bits (377), Expect = 7e-37
Identities = 133/483 (27%), Positives = 202/483 (41%), Gaps = 35/483 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT AP I P V Q TL C G+P P RW K +++ + + ++ G
Sbjct: 884 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 943
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R D G Y C A+N GT ++ ++ V VL + + + +G
Sbjct: 944 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 997
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N
Sbjct: 998 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 1055
Query: 185 AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
AG + + L ++++P + P ++ G VT C V P P + W
Sbjct: 1056 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 1114
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ + R L GS+++ +D G Y C A N G V+ + L V+ PP I
Sbjct: 1115 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVHVPPKIQ 1174
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
P + V+ G C A G P P + WS G+ ++ D H + DG L
Sbjct: 1175 RGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TL 1226
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKS 413
+I+ +D+ C A N AG+ L V +D PP T + Q
Sbjct: 1227 SIDQATPSDA-GIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQ 1282
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASS 471
FPC A TP+P I W G L + ++ DGT LV+ + D+G Y CVA +
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVN 1342
Query: 472 RHG 474
G
Sbjct: 1343 EAG 1345
Score = 155 bits (377), Expect = 7e-37
Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
P I P + V Q + C A G+P P I W KGG ++V H P G L +
Sbjct: 1171 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 1230
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
AT SDAG+Y C ATN GT + TLHV LEP + Q +
Sbjct: 1231 ATP----SDAGIYTCVATNIAGTDETE-ITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 1285
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C P +G+P+P + W NG+ L L DG LVI D G Y C+A N A
Sbjct: 1286 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 1344
Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
GT E LK+H+ P + + +V C V G P P ++W +
Sbjct: 1345 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 1402
Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
++ +++G L+L D G YSC+A N G + V PP+I PN
Sbjct: 1403 ESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 1462
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V+V C G P P + W +G +F G + D VL + +
Sbjct: 1463 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 1515
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
+ND + C+ N AG KLT+ PP I G ++ ++ I S+ C
Sbjct: 1516 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 1569
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
P P I WY +G+ ++ + + + G L + SDS TYTC
Sbjct: 1570 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 1618
Score = 154 bits (373), Expect = 2e-36
Identities = 130/464 (28%), Positives = 214/464 (46%), Gaps = 37/464 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V +++P L C A G P+P+I W K V + + I +G + + T + DAG
Sbjct: 1838 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 1894
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
Y C ATN+ G + ++ LHV E LE K + + V LEC G+P
Sbjct: 1895 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1949
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
P + W K+ + L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L
Sbjct: 1950 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 2006
Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
++H+ P I+G ++VA + V +C G P P + W + + ++VL G
Sbjct: 2007 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 2065
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L L + ++D G Y+C A N+ G L VY PP+I +V+V C
Sbjct: 2066 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 2125
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ P PT+ W +G+ + PG+S + + +VL I D D+ C A
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 2176
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-SMAVFPCTAICTPEPIIAWYF 433
N AG + + + PP I + Q I+ ++ C + P P + W
Sbjct: 2177 TNVAGKTEKNYNVNIWV----PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232
Query: 434 EGEALIQNH--RRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
+G ++ + R + + G L + +KSD+ Y+CVAS+ G
Sbjct: 2233 KGSPVLTDSMGRVRILSGGRQLQISIAEKSDAALYSCVASNVAG 2276
Score = 152 bits (369), Expect = 6e-36
Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)
Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG
Sbjct: 3525 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 3581
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + +V D G Y C A++ G + +HV EP + V
Sbjct: 3582 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 3639
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N
Sbjct: 3640 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 3696
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
AG + + L +++ P + GP+ +V S +C G P P + WR+ G
Sbjct: 3697 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 3755
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++
Sbjct: 3756 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 3813
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V C ATG P+P++ W G+ ++ +++ Y + G V+ +
Sbjct: 3814 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 3866
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D T C+ N AG LTV + PP I + P++ + + AV CTA
Sbjct: 3867 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 3921
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W G L+ + + + G + + + +G YTCVA + G
Sbjct: 3922 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 3974
Score = 151 bits (366), Expect = 1e-35
Identities = 138/476 (28%), Positives = 204/476 (42%), Gaps = 32/476 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I V V + P L C A G P+P++ W K G V S ++ + +GG L
Sbjct: 2011 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 2069
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
T ++ SD G Y C A N+ G + R+ L V V E ++ V L C
Sbjct: 2070 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 2125
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
P P + W K+G LL + + L I+DA+ D GRY C A N AG E
Sbjct: 2126 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAGKTE 2184
Query: 191 SAIATLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL 246
+ I + P I G +++ T G+ ++ C G P P+++W++ +
Sbjct: 2185 KNY-NVNIWVPPN-IGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSM 2242
Query: 247 GRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---PNSV 302
GRV++L G L++ +D YSC A N G L VY P+I S P +
Sbjct: 2243 GRVRILSGGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEI 2302
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V G C G P PT+ W +G+ I K + D +L + +
Sbjct: 2303 IVTRGKSISLECEVQGIPPPTVTWMKDGHPLI--------KAKGVEILDEGHILQLKNIH 2354
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAVFPCT 420
+D+ VC AVN AG + + L+V + PP II N P N ++ K+ C
Sbjct: 2355 VSDT-GRYVCVAVNVAGMTDKKYDLSVHA----PPSIIGNHRSPENISVVEKNSVSLTCE 2409
Query: 421 AICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P I W+ +G + N R ++ L L D+G YTCV + G+
Sbjct: 2410 ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGE 2465
Score = 149 bits (362), Expect = 5e-35
Identities = 128/454 (28%), Positives = 194/454 (42%), Gaps = 34/454 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP P I W K G L+ IL G + +V S+ G+Y C A N+
Sbjct: 1754 LDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 1810
Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G + T+HV + L + + V L+C+ G P P++ W K+ Q +
Sbjct: 1811 AGDHKKEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 1867
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ G L I DAGRY C+A NAAG + I L +H P L +
Sbjct: 1868 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 1926
Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262
+ + V +C+ G+P+P + W R +G +M L R +++D +++
Sbjct: 1927 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1981
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P
Sbjct: 1982 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 2041
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W +G+ F + V G +L + +D+ C AVN AG
Sbjct: 2042 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 2093
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
L V PP I N ++ I C + P P + W +G L++
Sbjct: 2094 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 2148
Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+++ N L ++D D+G YTC A++ GK
Sbjct: 2149 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAGK 2182
Score = 149 bits (361), Expect = 6e-35
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL +
Sbjct: 700 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 759
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+ T DAG Y C A N G A + TL V F EP G V L C
Sbjct: 760 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 814
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+G PEP + W++ +F S + + G L I + +D G Y C A N
Sbjct: 815 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 873
Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
G +S T+ + P + P G +T C + G+P+P+ W + SA
Sbjct: 874 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 933
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++
Sbjct: 934 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 991
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G C A+G P+P++ WS +G S K+ A A DG + +
Sbjct: 992 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 1042
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
+ VC+A N AG + + +LTV RP +Q P++
Sbjct: 1043 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 1099
Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
PC P PII W E + + + R G++ + + SDSG Y CVA++ G
Sbjct: 1100 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNV 1159
Query: 477 VWSGALLVDSP 487
+ L V P
Sbjct: 1160 TQAVKLNVHVP 1170
Score = 149 bits (361), Expect = 6e-35
Identities = 121/466 (25%), Positives = 198/466 (42%), Gaps = 24/466 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV +L C + G P P + W K G V++D+ + G L+ + SDA
Sbjct: 2206 LTVIEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQISIAE-KSDA 2264
Query: 81 GVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
+Y C A+N GTA+ N +++ P +G ++ LEC +G P P
Sbjct: 2265 ALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLEC-EVQGIPPPT 2323
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
V W K+G L+ + ++D G+++ +++ +D GRY C+A N AG + L +
Sbjct: 2324 VTWMKDGHPLI--KAKGVEILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSV 2380
Query: 199 HIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
H P +I PE++ +SV+ C G PLP + W + ++ V++L G
Sbjct: 2381 HAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLS-NSVRILSGG 2439
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARF 312
LRL + D G+Y+C N+ G L+V PP I + V V+
Sbjct: 2440 RMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVPPHIVGENTLEDVKVKEKQSVTL 2499
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
TC TG P P + W +G P + +H + G L I + + C
Sbjct: 2500 TCEVTGNPVPEITWHKDGQ-----PLQEDEAHH---IISGGRFLQITNVQVPHT-GRYTC 2550
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A + AG L V P + T+ + S C A P I W+
Sbjct: 2551 LASSPAGHKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWF 2610
Query: 433 FEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKYV 477
+G L N + G TL + + + ++G Y+CVA++ G+ +
Sbjct: 2611 KDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMI 2656
Score = 147 bits (355), Expect = 3e-34
Identities = 138/533 (25%), Positives = 230/533 (43%), Gaps = 34/533 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P +I+ P +VTV + A L C + + W + V +++ R A
Sbjct: 518 EPPPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLE 577
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVL 127
L++ +DAG Y C ++ G++ A++ + V + + P+++ G V +
Sbjct: 578 LKSVK---FNDAGEYHCMVSSEGGSSA---ASVFLTVQEPPKVTVMPKNQSFTGGSEVSI 631
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P+P + W N ++ G R + G L I++A DAG Y C+A N+AG
Sbjct: 632 MC-SATGYPKPKIAWTVNDMFIV--GSHRYRMTSDGTLFIKNAAPKDAGIYGCLASNSAG 688
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T + +TL+ P L+ +++ G +C+ G P P V W + G +
Sbjct: 689 T-DKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFK--GDLELRPS 745
Query: 248 RVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++D G L++ D G+Y+C A N G + L V PP P V++E
Sbjct: 746 TFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDVGSPPVFIQEPADVSME 805
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVTVLTINDTD 362
G+ C G PEPT+ W N I F S + A+F +L + +D
Sbjct: 806 IGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALF----ILNLWASD 861
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K T +C A N G ++ + TVT P+I PS + PCT +
Sbjct: 862 K----GTYICEAENQFGK--IQSETTVTV-TGLVAPLIGISPSVANVIEGQQLTLPCTLL 914
Query: 423 C-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W L+QN V +DG+L ++ + D G YTCVAS+ G + +
Sbjct: 915 AGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTS 974
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
++V + P I + +S++ G P + ++ WS+ ++ S+S
Sbjct: 975 VVVH--VLPTIQHGQQI-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 1024
Score = 140 bits (339), Expect = 3e-32
Identities = 126/466 (27%), Positives = 185/466 (39%), Gaps = 31/466 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V +L C + P P I WYK G ++ TH IL G + ++ SD
Sbjct: 3069 VNVREGTSVSLECESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 3125
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N G +N L+V V E E + V L C G P P +
Sbjct: 3126 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 3183
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I
Sbjct: 3184 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 3242
Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
+ P + P DV G +V C G P P + W + + R++V +GS
Sbjct: 3243 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 3302
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
L + + +D G+Y+C A N G L VY P+I + + V
Sbjct: 3303 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 3362
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C ATG P P + W G + P S + A + ++D C
Sbjct: 3363 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 3413
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
A N AG L V + PP + N + + + S C TP P +A
Sbjct: 3414 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 3468
Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W +G+ L + H T+ L L + DSG YTC+AS+ G+
Sbjct: 3469 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 3514
Score = 128 bits (309), Expect = 1e-28
Identities = 128/486 (26%), Positives = 195/486 (40%), Gaps = 50/486 (10%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +++V +L C A G P P+I W+K G V IL G + L T
Sbjct: 2393 PENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQT---TM 2449
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECLPPRG 134
DAG Y C N+ G R + L V V + E LE + Q T+ E G
Sbjct: 2450 EDAGQYTCVVRNAAGEER-KIFGLSVLVPPHIVGENTLEDVKVKEKQSVTLTCEVT---G 2505
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAI 193
+P P + W K+GQ L D H++ GG L I + + GRY C+A + AG + +
Sbjct: 2506 NPVPEITWHKDGQPL--QEDEAHHIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563
Query: 194 ATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ L + + P + PEDV S + C P + W + G + R
Sbjct: 2564 S-LNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKD--GTPLESNR 2620
Query: 249 -VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--------LS 298
+++L G +L++ N + G YSC A N G + + VY PP IN LS
Sbjct: 2621 NIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS 2680
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P V ++ N C A P ++ W +G P S D H +G T L I
Sbjct: 2681 PKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQ-----PLKSDD--HVNIAANGHT-LQI 2732
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--------PIITNGPSNQTLP 410
+ +D+ C A N AG + + + NG + +
Sbjct: 2733 KEAQISDT-GRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVII 2791
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVA 469
++++ C P P + WY +G L + + + G L + D+G YTCVA
Sbjct: 2792 NNPISLY-CETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRVLQIPRAKVEDAGRYTCVA 2850
Query: 470 SSRHGK 475
+ G+
Sbjct: 2851 VNEAGE 2856
Score = 126 bits (304), Expect = 5e-28
Identities = 132/495 (26%), Positives = 209/495 (42%), Gaps = 54/495 (10%)
Query: 12 PYII-EQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P+I+ E L DV V Q TL C G+P P I W+K G + D I+ G FL
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHIISGGR--FL 2535
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL----EPESKQSAQGDTV 125
+ T+ +V G Y C A++ G +SR+ +L+V V + PE
Sbjct: 2536 QITNVQV-PHTGRYTCLASSPAG-HKSRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPT 2593
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C P + W K+G L + + R+ L G L I +A++ +AGRY C+A N
Sbjct: 2594 SLVC-EAYSYPPATITWFKDGTPLESNRNIRI-LPGGRTLQILNAQEDNAGRYSCVATNE 2651
Query: 186 AGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
AG +K++I P + G P++V + +++T +C P + W +
Sbjct: 2652 AGEMIKHY-EVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYK 2710
Query: 238 SAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI- 295
G V + +G +L++ ++D G Y+C A N G + + PPS
Sbjct: 2711 D-GQPLKSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQ 2769
Query: 296 ------NLSPNSVNVES-----GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
N+ N E+ N C P PT+ W +G+ P S DK
Sbjct: 2770 KLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGH-----PLTSSDK- 2823
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG- 403
+ G VL I D+ C AVN AG ++ + V PPII
Sbjct: 2824 --VLILPGGRVLQIPRAKVEDA-GRYTCVAVNEAGEDSLQYDVRVL-----VPPIIKGAN 2875
Query: 404 ---PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDK 459
P T+ + A+ C + +P P +W +G+ L++ +H + ++N L + +
Sbjct: 2876 SDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRILQILNTQI 2935
Query: 460 SDSGTYTCVASSRHG 474
+D G Y CVA + G
Sbjct: 2936 TDIGRYVCVAENTAG 2950
Score = 123 bits (296), Expect = 4e-27
Identities = 107/421 (25%), Positives = 180/421 (42%), Gaps = 26/421 (6%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
SD G Y C A +S GT R++ V+ ++ P + G+ VL CL + +
Sbjct: 492 SDEGFYECIAVSSAGTGRAQ-TFFDVSEPPPVIQV-PNNVTVTPGERAVLTCL-IISAVD 548
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
N+ W++N + + +R+ + +L ++ + DAG Y C+ + G+ +A L
Sbjct: 549 YNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGS-SAASVFLT 607
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+ P + P++ GS V+ C G P P + W + + R ++ DG+L
Sbjct: 608 VQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVN-DMFIVGSHRYRMTSDGTL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ N D G Y C A NS G + L + P + + + + V G++ C +
Sbjct: 667 FIKNAAPKDAGIYGCLASNSAGTDKQNSTLRYIEAPKLMVVQSELLVALGDITVMECKTS 726
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVN 376
G P P + W F G + + D + +L I +T D+ C A+N
Sbjct: 727 GIPPPQVKW---------FKGDLELRPSTFLIIDPLLGLLKIQETQDLDA-GDYTCVAIN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + GK+T+ D PP+ P++ ++ I S PC PEP I W
Sbjct: 777 EAGRA--TGKITL---DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDN 831
Query: 437 ALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
I + +V++ G L + +L SD GTY C A ++ GK + V + P
Sbjct: 832 MPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPL 891
Query: 492 I 492
I
Sbjct: 892 I 892
Score = 103 bits (246), Expect = 5e-21
Identities = 88/327 (26%), Positives = 144/327 (44%), Gaps = 20/327 (6%)
Query: 164 NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
NL I +D G Y+CIA ++AGT A + P +I P +V G C
Sbjct: 483 NLDIAKVTLSDEGFYECIAVSSAGTGR-AQTFFDVSEPPPVIQVPNNVTVTPGERAVLTC 541
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
+ ++ W+R+ + R++ L + SL L +V D GEY C + G+ +
Sbjct: 542 LIISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSA 601
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
AS +LTV +PP + + P + + G+ C+ATG P+P + W+V N I +
Sbjct: 602 ASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTV--NDMFI---VGSH 656
Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
+Y T+ DG L I + D+ C A N AG+ L + P ++
Sbjct: 657 RYRMTS--DG--TLFIKNAAPKDA-GIYGCLASNSAGTDKQNSTLRYI---EAPKLMVVQ 708
Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND--GTLVLKDLDKS 460
S + + + V C P P + W F+G+ ++ + + G L +++
Sbjct: 709 --SELLVALGDITVMECKTSGIPPPQVKW-FKGDLELRPSTFLIIDPLLGLLKIQETQDL 765
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G YTCVA + G+ L V SP
Sbjct: 766 DAGDYTCVAINEAGRATGKITLDVGSP 792
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I +P++ + LNC+A G P P I W + G + D ++L
Sbjct: 4434 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 4493
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
L+ A D + C A N G+ R
Sbjct: 4494 LYIADAQ----KEDTSEFECVARNLMGSVLVR 4521
>AJ306906-1|CAC37630.1| 2673|Homo sapiens fibulin-6 protein.
Length = 2673
Score = 204 bits (497), Expect = 2e-51
Identities = 152/481 (31%), Positives = 219/481 (45%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFF 68
E P I QP ++ V + P L C A G+PSP I W K G+ V S + ++LP+GGL
Sbjct: 1024 EPPVIQPQPSELHVILNNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGGLQI 1083
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVV 126
RA V DAG Y C A N GTA + L+V V + P K+ A +
Sbjct: 1084 SRA----VREDAGTYMCVAQNPAGTALGK-IKLNVQVPPV---ISPHLKEYVIAVDKPIT 1135
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G P P++ W K+G+ ++ R ++ G+L I + DAG Y C+A N A
Sbjct: 1136 LSC-EADGLPPPDITWHKDGRAIV--ESIRQRVLSSGSLQITFVQPGDAGHYTCMAANVA 1192
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ S L +H+ P + + S C G P P + W++ L
Sbjct: 1193 GS-SSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLL 1251
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+ G L L+NV+L D G Y+C A N+ G + + LTV+ P+ P V++
Sbjct: 1252 GKYTAEPYGELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVLPTFTELPGDVSLNK 1311
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R +C ATG P P + W+ N I P H +V +G + L I K DS
Sbjct: 1312 GEQLRLSCKATGIPLPKLTWTFNNN---IIPA------HFDSV-NGHSELVIERVSKEDS 1361
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
T VC+A N G G + V PP + PS+ P+ A+ C P
Sbjct: 1362 -GTYVCTAENSVGFVKAIGFVYV----KEPPVFKGDYPSHWIEPLGGNAILNCEVKGDPT 1416
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G + +HR +G+L + D+G YTCVA++ G S +L + S
Sbjct: 1417 PTIQWNRKGVDIEISHRIRQLGNGSLAIYGTVNEDAGDYTCVATNEAGVVERSMSLTLQS 1476
Query: 487 P 487
P
Sbjct: 1477 P 1477
Score = 188 bits (457), Expect = 1e-46
Identities = 147/478 (30%), Positives = 210/478 (43%), Gaps = 28/478 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV--SDTHRSILPAGGLFFL 69
P I ++P D V +H PA + C A G P P+I W K G+ ++ D +R IL +G + L
Sbjct: 935 PSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIRLLPRGDGYR-ILSSGAIEIL 993
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
AT + AG Y C A N+ G+A R+ TLHV + +P + ++L C
Sbjct: 994 -ATQ---LNHAGRYTCVARNAAGSAH-RHVTLHVHE-PPVIQPQPSELHVILNNPILLPC 1047
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G+P P + W+K G + G + L GG L I A + DAG Y C+A+N AGT
Sbjct: 1048 -EATGTPSPFITWQKEGINVNTSGRNHAVLPSGG-LQISRAVREDAGTYMCVAQNPAGTA 1105
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
I L + + P + ++ V +T C G P PD+ W + G + R
Sbjct: 1106 LGKIK-LNVQVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKD-GRAIVESIRQ 1163
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
+VL GSL++ V D G Y+C A N G+ S S LTV+ PP I + V +
Sbjct: 1164 RVLSSGSLQITFVQPGDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQ 1223
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P P + W + ++ + KY A + L + + DS
Sbjct: 1224 AILPCVADGIPTPAINWKKD---NVLLANL-LGKYTAEPYGE----LILENVVLEDS-GF 1274
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG LTV P T P + +L C A P P +
Sbjct: 1275 YTCVANNAAGEDTHTVSLTV-----HVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKL 1329
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
W F +I H +V LV++ + K DSGTY C A + G G + V P
Sbjct: 1330 TWTFNNN-IIPAHFDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEP 1386
Score = 186 bits (452), Expect = 6e-46
Identities = 151/574 (26%), Positives = 247/574 (43%), Gaps = 34/574 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I P + + ++ L C A G P+P I W K G ++ + R + G
Sbjct: 745 LTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHARYSILENG 804
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+++ H +D G Y C ATN+ GT R R L V V P +
Sbjct: 805 FLHIQSAH---VTDTGRYLCMATNAAGTDR-RRIDLQVHV-PPSIAPGPTNMTVIVNVQT 859
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIARN 184
L C G P+P++ W+KNG L D + + L+ G+LVI D Y+C N
Sbjct: 860 TLAC-EATGIPKPSINWRKNGHLLNVDQNQNSYRLLSSGSLVIISPSVDDTATYECTVTN 918
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG + + L + + P + P D + + C G P P + W ++ G +
Sbjct: 919 GAGDDKRTV-DLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKN-GIRLL 976
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P G ++L G++ + L G Y+C A N+ G+ L V++PP I P+ ++
Sbjct: 977 PRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAGSAHRHVTLHVHEPPVIQPQPSELH 1036
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V N C ATG P P + W EG + + HA G L I+ +
Sbjct: 1037 VILNNPILLPCEATGTPSPFITWQKEGINV-----NTSGRNHAVLPSGG---LQISRAVR 1088
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T +C A N AG++ + KL V + PP+I+ + + C A
Sbjct: 1089 EDA-GTYMCVAQNPAGTALGKIKLNV-----QVPPVISPHLKEYVIAVDKPITLSCEADG 1142
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P I W+ +G A++++ R+ V + G+L + + D+G YTC+A++ G S L
Sbjct: 1143 LPPPDITWHKDGRAIVESIRQRVLSSGSLQITFVQPGDAGHYTCMAANVAGSSSTSTKLT 1202
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT--LSWSQNNKIGSSSILGYQVE 541
V P P I R+ + ++ I V D T ++W ++N + ++ + Y E
Sbjct: 1203 VHVP--PRI---RSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKYTAE 1257
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRV--HQTHYV 573
+ E + N +S + +A TH V
Sbjct: 1258 PYG-ELILENVVLEDSGFYTCVANNAAGEDTHTV 1290
Score = 177 bits (431), Expect = 2e-43
Identities = 141/487 (28%), Positives = 213/487 (43%), Gaps = 36/487 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P +I L + +A +P TL+C A G P P I W+K G +V + +L +G L
Sbjct: 1114 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 1173
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G DAG Y C A N G++ S T+HV R + +L
Sbjct: 1174 TFVQPG----DAGHYTCMAANVAGSSSTSTKLTVHVP---PRIRSTEGHYTVNENSQAIL 1226
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ G P P + WKK+ LL + + G L++++ D+G Y C+A NAAG
Sbjct: 1227 PCVAD-GIPTPAINWKKDN-VLLANLLGKYTAEPYGELILENVVLEDSGFYTCVANNAAG 1284
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
++ +L +H+ P P DV G + C+ G PLP + W + +P
Sbjct: 1285 -EDTHTVSLTVHVLPTFTELPGDVSLNKGEQLRLSCKATGIPLPKLTW--TFNNNIIPAH 1341
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V L ++ V D G Y C AENSVG V A G++ V +PP S +E
Sbjct: 1342 FDSVNGHSELVIERVSKEDSGTYVCTAENSVGFVKAIGFVYVKEPPVFKGDYPSHWIEPL 1401
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G P PT+ W+ +G I + + + A++ T+N+ D D
Sbjct: 1402 GGNAILNCEVKGDPTPTIQWNRKGVDIEISHRIRQLGNGSLAIYG-----TVNE-DAGD- 1454
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG LT+ S PPIIT P + + C A P+
Sbjct: 1455 ---YTCVATNEAGVVERSMSLTLQS-----PPIITLEPVETVINAGGKIILNCQATGEPQ 1506
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
P I W +G ++ + R NV ++ +L + D K D+ + CVA + G++LV
Sbjct: 1507 PTITWSRQGHSISWDDRVNVLSNNSLYIADAQKEDTSEFECVARN------LMGSVLVRV 1560
Query: 487 PINPNIH 493
P+ +H
Sbjct: 1561 PVIVQVH 1567
Score = 167 bits (406), Expect = 2e-40
Identities = 149/489 (30%), Positives = 207/489 (42%), Gaps = 36/489 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHG 74
E P DV+V + L C A G P+P I+W K G + S +T R + A G +G
Sbjct: 289 EIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTL--NIYG 346
Query: 75 RVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ SD G Y C ATN G R N ++V + E E + ++ +EC
Sbjct: 347 ALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIEC-RAT 405
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P + W KNG L R+ L G + I A+ +D Y C+A N AG ++
Sbjct: 406 GTPPPQINWLKNGLPLPLSSHIRL-LAAGQVIRIVRAQVSDVAVYTCVASNRAGV-DNKH 463
Query: 194 ATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---R 248
L++ P + G E++ GSS + C G P P + W R PLG
Sbjct: 464 YNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRD----GQPLGLDAH 519
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP--NSVNVE 305
+ V G L+L D G+Y+C A N G VS L V +PP IN S ++V
Sbjct: 520 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 579
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
N TC A+G P P M W +G P D+ G VL I+ D
Sbjct: 580 VNNPLELTCIASGIPAPKMTWMKDGR-----PLPQTDQ---VQTLGGGEVLRISTAQVED 631
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAICT 424
+ C A + AG + V PP I T+ P + T+ C +
Sbjct: 632 T-GRYTCLASSPAGDDDKEYLVRV----HVPPNIAGTDEPRDITVLRNRQVTLECKSDAV 686
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P+I W GE L R + + G L + + D D+ YTCVAS+ GK L
Sbjct: 687 PPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTANYTCVASNIAGKTTREFILT 746
Query: 484 VDSPINPNI 492
V+ P PNI
Sbjct: 747 VNVP--PNI 753
Score = 155 bits (377), Expect = 7e-37
Identities = 126/452 (27%), Positives = 191/452 (42%), Gaps = 31/452 (6%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
+ CRA G+P P I W K G+ + +H +L AG + +R +V SD VY C A+N
Sbjct: 400 IECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQV--IRIVRAQV-SDVAVYTCVASNR 456
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
G A + + E +G + + C+ G+P P++ W ++GQ L
Sbjct: 457 AGVDNKHYNLQVFAPPNMDNSMGTEEITVLKGSSTSMACITD-GTPAPSMAWLRDGQPLG 515
Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP-- 208
D + G L + A D+G+Y CIA N AG S LK+ ++P I G
Sbjct: 516 LDAHLTVS-THGMVLQLLKAETEDSGKYTCIASNEAG-EVSKHFILKV-LEPPHINGSEE 572
Query: 209 -EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDGS-LRLDNVILA 265
E++ + + C G P P + W + G +P +V+ L G LR+ +
Sbjct: 573 HEEISVIVNNPLELTCIASGIPAPKMTWMKD--GRPLPQTDQVQTLGGGEVLRISTAQVE 630
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPT 323
D G Y+C A + G + V+ PP+I P + V C + P P
Sbjct: 631 DTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEPRDITVLRNRQVTLECKSDAVPPPV 690
Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
+ W G R P + G L IN+ D D+ N C A N AG +
Sbjct: 691 ITWLRNGERLQATP--------RVRILSGGRYLQINNADLGDTAN-YTCVASNIAGKTTR 741
Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
LTV PP I GP + + + V C A P P I W +G L NH
Sbjct: 742 EFILTV-----NVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAGNHA 796
Query: 444 R-NVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
R ++ +G L ++ +D+G Y C+A++ G
Sbjct: 797 RYSILENGFLHIQSAHVTDTGRYLCMATNAAG 828
Score = 152 bits (369), Expect = 6e-36
Identities = 131/473 (27%), Positives = 207/473 (43%), Gaps = 31/473 (6%)
Query: 10 EAPYI--IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
E P+I E+ +++V + P L C A G P+P + W K G L +D +++ GG
Sbjct: 563 EPPHINGSEEHEEISVIVNNPLELTCIASGIPAPKMTWMKDGRPLPQTDQVQTL---GGG 619
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + +V D G Y C A++ G + +HV EP + V
Sbjct: 620 EVLRISTAQVE-DTGRYTCLASSPAGDDDKEYLVRVHVPP-NIAGTDEPRDITVLRNRQV 677
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARN 184
LEC P P + W +NG+ L R+ ++ GG L I +A D Y C+A N
Sbjct: 678 TLECKSD-AVPPPVITWLRNGERL--QATPRVRILSGGRYLQINNADLGDTANYTCVASN 734
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GG 242
AG + + L +++ P + GP+ +V S +C G P P + WR+ G
Sbjct: 735 IAG-KTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECIAEGVPTPRITWRKDGAVLAG 793
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
N R +L++G L + + + D G Y C A N+ G L V+ PPSI P ++
Sbjct: 794 NH--ARYSILENGFLHIQSAHVTDTGRYLCMATNAAGTDRRRIDLQVHVPPSIAPGPTNM 851
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V C ATG P+P++ W G+ ++ +++ Y + G V+ +
Sbjct: 852 TVIVNVQTTLACEATGIPKPSINWRKNGH--LLNVDQNQNSYRLLS--SGSLVII---SP 904
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D T C+ N AG LTV + PP I + P++ + + AV CTA
Sbjct: 905 SVDDTATYECTVTNGAGDDKRTVDLTV-----QVPPSIADEPTDFLVTKHAPAVITCTAS 959
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W G L+ + + + G + + + +G YTCVA + G
Sbjct: 960 GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIEILATQLNHAGRYTCVARNAAG 1012
Score = 137 bits (331), Expect = 3e-31
Identities = 134/466 (28%), Positives = 203/466 (43%), Gaps = 29/466 (6%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++TV + +L C G P P + W K + +T+ I+P G L+ +V SD
Sbjct: 11 NLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRT--LQIIRAKV-SD 67
Query: 80 AGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPE 137
G Y C A N G ++ + + T++V ++ E S + +G +V LE P
Sbjct: 68 GGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLE-XESNAVPP 126
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P + W KNG+ ++ + L DG L I+ A +D G+Y C A N AG R+ L
Sbjct: 127 PVITWYKNGR-MITESTHVEILADGQMLHIKKAEVSDTGQYVCRAINVAG-RDDKNFHLN 184
Query: 198 IHIKPYLITGPE-DVVAQTGSS-VTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDD 254
+++ P I GPE +V+ +T S+ VT C G P P + W ++ N V++L
Sbjct: 185 VYVPP-SIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSG 243
Query: 255 GS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS--PNSVNVESGNVAR 311
GS L++ +D G Y+C A N G +L++ PPS+ + P+ V+V G
Sbjct: 244 GSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLLGENVE 303
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
C A G P P + W +G + I R + A + +DT K
Sbjct: 304 LVCNANGIPTPLIQWLKDG-KPIASGETERIRVSANGSTLNIYGALTSDTGK------YT 356
Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP--IKSMAVFPCTAICTPEPII 429
C A N AG L V P I N + L + + C A TP P I
Sbjct: 357 CVATNPAGEEDRIFNLNVYV----TPTIRGNKDEAEKLMTLVDTSINIECRATGTPPPQI 412
Query: 430 AWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
W G L + +H R + + + SD YTCVAS+R G
Sbjct: 413 NWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAG 458
Score = 136 bits (328), Expect = 6e-31
Identities = 125/466 (26%), Positives = 184/466 (39%), Gaps = 31/466 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V +L + P P I WYK G ++ TH IL G + ++ SD
Sbjct: 107 VNVREGTSVSLEXESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE---VSDT 163
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N G +N L+V V E E + V L C G P P +
Sbjct: 164 GQYVCRAINVAG-RDDKNFHLNVYVPPSIEGPEREVIVETISNPVTLTC-DATGIPPPTI 221
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
W KN + + + ++ GG+ L I ++ +D+G Y CIA N G + L I
Sbjct: 222 AWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEG-KAQKYYFLSIQ 280
Query: 200 IKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS 256
+ P + P DV G +V C G P P + W + + R++V +GS
Sbjct: 281 VPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGS 340
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV---ARF 312
L + + +D G+Y+C A N G L VY P+I + + V
Sbjct: 341 TLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINI 400
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C ATG P P + W G + P S + A + ++D C
Sbjct: 401 ECRATGTPPPQINWLKNG---LPLPLSSHIRLLAAGQVIRIVRAQVSDV------AVYTC 451
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIA 430
A N AG L V + PP + N + + + S C TP P +A
Sbjct: 452 VASNRAGVDNKHYNLQVFA-----PPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMA 506
Query: 431 WYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W +G+ L + H T+ L L + DSG YTC+AS+ G+
Sbjct: 507 WLRDGQPLGLDAHLTVSTHGMVLQLLKAETEDSGKYTCIASNEAGE 552
Score = 115 bits (277), Expect = 9e-25
Identities = 99/354 (27%), Positives = 156/354 (44%), Gaps = 28/354 (7%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESA 192
G P P++ W KN Q + + ++ +V GG L I A+ +D G Y CIA N AG +
Sbjct: 28 GFPPPDLSWLKNEQPIKLNTNTL--IVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKK 85
Query: 193 IATLKIHIKPYLITGPED----VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ L +++ P + + V + G+SV+ + P P + W ++ G
Sbjct: 86 FS-LTVYVPPSIKDHDSESLSVVNVREGTSVSLEXESNAVPPPVITWYKN-GRMITESTH 143
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
V++L DG L + ++D G+Y C A N G + +L VY PPSI V VE+
Sbjct: 144 VEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYVPPSIEGPEREVIVETI 203
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
N TC ATG P PT+ W R + + G + L I + +DS
Sbjct: 204 SNPVTLTCDATGIPPPTIAWLKNHKR------IENSDSLEVRILSGGSKLQIARSQHSDS 257
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPCTAICT 424
N C A N G + L++ + PP + PS+ ++ + C A
Sbjct: 258 GN-YTCIASNMEGKAQKYYFLSI-----QVPPSVAGAEIPSDVSVLLGENVELVCNANGI 311
Query: 425 PEPIIAWYFEGEALIQNHRRNV---TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
P P+I W +G+ + + N TL + SD+G YTCVA++ G+
Sbjct: 312 PTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYTCVATNPAGE 365
Score = 91.5 bits (217), Expect = 2e-17
Identities = 81/286 (28%), Positives = 119/286 (41%), Gaps = 28/286 (9%)
Query: 202 PYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
P + GP E++ + ++ C V G P PD+ W ++ + + V +L++
Sbjct: 1 PPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKLNTNTLIVPGGRTLQI 60
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI----NLSPNSVNVESGNVARFTCT 315
++D GEY+C A N G LTVY PPSI + S + VNV G
Sbjct: 61 IRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEXE 120
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
+ P P + W G M + H + DG +L I + +D+ VC A+
Sbjct: 121 SNAVPPPVITWYKNGR-------MITESTHVEILADG-QMLHIKKAEVSDT-GQYVCRAI 171
Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL--PIKSMAVFPCTAICTPEPIIAWYF 433
N AG L V PP I GP + + I + C A P P IAW
Sbjct: 172 NVAGRDDKNFHLNVYV----PPSI--EGPEREVIVETISNPVTLTCDATGIPPPTIAW-L 224
Query: 434 EGEALIQN----HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ I+N R ++ L + SDSG YTC+AS+ GK
Sbjct: 225 KNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGK 270
Score = 38.7 bits (86), Expect = 0.13
Identities = 24/92 (26%), Positives = 37/92 (40%), Gaps = 4/92 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T P I +P++ + LNC+A G P P I W + G + D ++L
Sbjct: 1472 LTLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNS 1531
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
L+ A D + C A N G+ R
Sbjct: 1532 LYIADAQ----KEDTSEFECVARNLMGSVLVR 1559
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 201 bits (491), Expect = 1e-50
Identities = 122/387 (31%), Positives = 190/387 (49%), Gaps = 23/387 (5%)
Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV 166
R EP+ G+TV C G+P+P + W +N L DSR++L+D G L+
Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRA-EGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 320
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQC 223
IQ+ ++TD G YQC+A+N AG ++ TL+ +P + P++ G SVT +C
Sbjct: 321 IQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLEC 380
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
G P P + W R G PL RV + G L + NV+ D GEY+C A N++ +
Sbjct: 381 SATGHPPPRISWTR---GDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDS 437
Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
V A+ ++ V P ++P V G F C A G P P + W+ G++ +S
Sbjct: 438 VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQ------LS 491
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
D+ H V T L I+ +D + C AVN GS V LTV R P+
Sbjct: 492 VDRRH--LVLSSGT-LRISGVALHD-QGQYECQAVNIIGSQKVVAHLTV---QPRVTPVF 544
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
+ PS+ T+ + + PC++ PEP I W +G + ++ + +++ +G L + D+ +
Sbjct: 545 ASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPA 604
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G Y CVA + G S L V+ P
Sbjct: 605 DAGRYECVARNTIGSASVSMVLSVNVP 631
Score = 171 bits (417), Expect = 1e-41
Identities = 119/391 (30%), Positives = 181/391 (46%), Gaps = 26/391 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLF 67
E P I +P D V CRA G+P P I W + + + +D+ ++L G L
Sbjct: 261 ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 320
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTV 125
+D G+Y C A N G +++ TL + R F ++P++ + G++V
Sbjct: 321 I----QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESV 376
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
LEC G P P + W + +T L D R+++ G L IQ+ Q D+G Y C A N
Sbjct: 377 TLEC-SATGHPPPRISWTRGDRTPL-PVDPRVNITPSGGLYIQNVVQGDSGEYACSATNN 434
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+ A A + + P P+D V G +V FQC G+P P + W + GG +
Sbjct: 435 IDS-VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTK--GGSQLS 491
Query: 246 LGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSV 302
+ R VL G+LR+ V L D+G+Y C+A N +G+ +LTV P P+
Sbjct: 492 VDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDT 551
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
VE G + C++ G PEP + W+ +G + K+H + +G LTIND
Sbjct: 552 TVEVGANVQLPCSSQGEPEPAITWNKDGVQV-----TESGKFHISP--EG--FLTINDVG 602
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
D+ C A N GS+ V L+V D
Sbjct: 603 PADA-GRYECVARNTIGSASVSMVLSVNVPD 632
Score = 138 bits (333), Expect = 1e-31
Identities = 91/291 (31%), Positives = 138/291 (47%), Gaps = 14/291 (4%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPA 63
Y S P + QP + V + TL C A G P P I W +G + D +I P+
Sbjct: 352 YFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPS 411
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
GGL+ G D+G Y C ATN+ + + A + V L +F + P+ + +G
Sbjct: 412 GGLYIQNVVQG----DSGEYACSATNNIDSVHA-TAFIIVQAL-PQFTVTPQDRVVIEGQ 465
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIA 182
TV +C +G+P P + W K G L D R HLV G L I D G+Y+C A
Sbjct: 466 TVDFQC-EAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRISGVALHDQGQYECQA 521
Query: 183 RNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
N G+++ A T++ + P + P D + G++V C G+P P + W + G
Sbjct: 522 VNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKD-GV 580
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
G+ + +G L +++V AD G Y C A N++G+ S S L+V P
Sbjct: 581 QVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 631
Score = 107 bits (258), Expect = 2e-22
Identities = 82/295 (27%), Positives = 126/295 (42%), Gaps = 19/295 (6%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRL 259
+P + + P+D +G++V F CR G+P P+++W R+ +M R+ +LDDG+L +
Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMI 321
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVY--DP--PSINLSPNSVNVESGNVARFTCT 315
N D+G Y C A+N G V Y P P+ + P + V G C+
Sbjct: 322 QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECS 381
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
ATG P P + W+ G+RT + P R + G+ + + D + CSA
Sbjct: 382 ATGHPPPRISWT-RGDRTPL-PVDPRVNITPSG---GLYIQNVVQGDSGE----YACSAT 432
Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
N S + V + P T P ++ + F C A P P+IAW G
Sbjct: 433 NNIDSVHATAFIIVQA-----LPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGG 487
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
L + R V + GTL + + D G Y C A + G L V + P
Sbjct: 488 SQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTP 542
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 201 bits (491), Expect = 1e-50
Identities = 122/387 (31%), Positives = 190/387 (49%), Gaps = 23/387 (5%)
Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV 166
R EP+ G+TV C G+P+P + W +N L DSR++L+D G L+
Sbjct: 240 RPRITSEPQDADVTSGNTVYFTCRA-EGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 298
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQC 223
IQ+ ++TD G YQC+A+N AG ++ TL+ +P + P++ G SVT +C
Sbjct: 299 IQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLEC 358
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
G P P + W R G PL RV + G L + NV+ D GEY+C A N++ +
Sbjct: 359 SATGHPPPRISWTR---GDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDS 415
Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
V A+ ++ V P ++P V G F C A G P P + W+ G++ +S
Sbjct: 416 VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQ------LS 469
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
D+ H V T L I+ +D + C AVN GS V LTV R P+
Sbjct: 470 VDRRH--LVLSSGT-LRISGVALHD-QGQYECQAVNIIGSQKVVAHLTV---QPRVTPVF 522
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
+ PS+ T+ + + PC++ PEP I W +G + ++ + +++ +G L + D+ +
Sbjct: 523 ASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPA 582
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G Y CVA + G S L V+ P
Sbjct: 583 DAGRYECVARNTIGSASVSMVLSVNVP 609
Score = 171 bits (417), Expect = 1e-41
Identities = 119/391 (30%), Positives = 181/391 (46%), Gaps = 26/391 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLF 67
E P I +P D V CRA G+P P I W + + + +D+ ++L G L
Sbjct: 239 ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 298
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTV 125
+D G+Y C A N G +++ TL + R F ++P++ + G++V
Sbjct: 299 I----QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESV 354
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
LEC G P P + W + +T L D R+++ G L IQ+ Q D+G Y C A N
Sbjct: 355 TLEC-SATGHPPPRISWTRGDRTPL-PVDPRVNITPSGGLYIQNVVQGDSGEYACSATNN 412
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+ A A + + P P+D V G +V FQC G+P P + W + GG +
Sbjct: 413 IDS-VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTK--GGSQLS 469
Query: 246 LGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSV 302
+ R VL G+LR+ V L D+G+Y C+A N +G+ +LTV P P+
Sbjct: 470 VDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDT 529
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
VE G + C++ G PEP + W+ +G + K+H + +G LTIND
Sbjct: 530 TVEVGANVQLPCSSQGEPEPAITWNKDGVQV-----TESGKFHISP--EG--FLTINDVG 580
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
D+ C A N GS+ V L+V D
Sbjct: 581 PADA-GRYECVARNTIGSASVSMVLSVNVPD 610
Score = 138 bits (333), Expect = 1e-31
Identities = 91/291 (31%), Positives = 138/291 (47%), Gaps = 14/291 (4%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPA 63
Y S P + QP + V + TL C A G P P I W +G + D +I P+
Sbjct: 330 YFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPS 389
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
GGL+ G D+G Y C ATN+ + + A + V L +F + P+ + +G
Sbjct: 390 GGLYIQNVVQG----DSGEYACSATNNIDSVHA-TAFIIVQAL-PQFTVTPQDRVVIEGQ 443
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIA 182
TV +C +G+P P + W K G L D R HLV G L I D G+Y+C A
Sbjct: 444 TVDFQC-EAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRISGVALHDQGQYECQA 499
Query: 183 RNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
N G+++ A T++ + P + P D + G++V C G+P P + W + G
Sbjct: 500 VNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKD-GV 558
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
G+ + +G L +++V AD G Y C A N++G+ S S L+V P
Sbjct: 559 QVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 609
Score = 107 bits (258), Expect = 2e-22
Identities = 82/295 (27%), Positives = 126/295 (42%), Gaps = 19/295 (6%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRL 259
+P + + P+D +G++V F CR G+P P+++W R+ +M R+ +LDDG+L +
Sbjct: 240 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMI 299
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVY--DP--PSINLSPNSVNVESGNVARFTCT 315
N D+G Y C A+N G V Y P P+ + P + V G C+
Sbjct: 300 QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECS 359
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
ATG P P + W+ G+RT + P R + G+ + + D + CSA
Sbjct: 360 ATGHPPPRISWT-RGDRTPL-PVDPRVNITPSG---GLYIQNVVQGDSGE----YACSAT 410
Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
N S + V + P T P ++ + F C A P P+IAW G
Sbjct: 411 NNIDSVHATAFIIVQA-----LPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGG 465
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
L + R V + GTL + + D G Y C A + G L V + P
Sbjct: 466 SQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTP 520
>AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated
antigen MG50 protein.
Length = 1496
Score = 201 bits (491), Expect = 1e-50
Identities = 122/387 (31%), Positives = 190/387 (49%), Gaps = 23/387 (5%)
Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV 166
R EP+ G+TV C G+P+P + W +N L DSR++L+D G L+
Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRA-EGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 320
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQC 223
IQ+ ++TD G YQC+A+N AG ++ TL+ +P + P++ G SVT +C
Sbjct: 321 IQNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLEC 380
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
G P P + W R G PL RV + G L + NV+ D GEY+C A N++ +
Sbjct: 381 SATGHPPPRISWTR---GDRTPLPVDPRVNITPSGGLYIQNVVQGDSGEYACSATNNIDS 437
Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
V A+ ++ V P ++P V G F C A G P P + W+ G++ +S
Sbjct: 438 VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGGSQ------LS 491
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
D+ H V T L I+ +D + C AVN GS V LTV R P+
Sbjct: 492 VDRRH--LVLSSGT-LRISGVALHD-QGQYECQAVNIIGSQKVVAHLTV---QPRVTPVF 544
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
+ PS+ T+ + + PC++ PEP I W +G + ++ + +++ +G L + D+ +
Sbjct: 545 ASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKDGVQVTESGKFHISPEGFLTINDVGPA 604
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSP 487
D+G Y CVA + G S L V+ P
Sbjct: 605 DAGRYECVARNTIGSASVSMVLSVNVP 631
Score = 171 bits (417), Expect = 1e-41
Identities = 119/391 (30%), Positives = 181/391 (46%), Gaps = 26/391 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG--VLVVSDTHRSILPAGGLF 67
E P I +P D V CRA G+P P I W + + + +D+ ++L G L
Sbjct: 261 ERPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLM 320
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREEFRLEPESKQSAQGDTV 125
+D G+Y C A N G +++ TL + R F ++P++ + G++V
Sbjct: 321 I----QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESV 376
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
LEC G P P + W + +T L D R+++ G L IQ+ Q D+G Y C A N
Sbjct: 377 TLEC-SATGHPPPRISWTRGDRTPL-PVDPRVNITPSGGLYIQNVVQGDSGEYACSATNN 434
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+ A A + + P P+D V G +V FQC G+P P + W + GG +
Sbjct: 435 IDS-VHATAFIIVQALPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTK--GGSQLS 491
Query: 246 LGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSV 302
+ R VL G+LR+ V L D+G+Y C+A N +G+ +LTV P P+
Sbjct: 492 VDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTPVFASIPSDT 551
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
VE G + C++ G PEP + W+ +G + K+H + +G LTIND
Sbjct: 552 TVEVGANVQLPCSSQGEPEPAITWNKDGVQV-----TESGKFHISP--EG--FLTINDVG 602
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
D+ C A N GS+ V L+V D
Sbjct: 603 PADA-GRYECVARNTIGSASVSMVLSVNVPD 632
Score = 138 bits (333), Expect = 1e-31
Identities = 91/291 (31%), Positives = 138/291 (47%), Gaps = 14/291 (4%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPA 63
Y S P + QP + V + TL C A G P P I W +G + D +I P+
Sbjct: 352 YFGSPARPTFVIQPQNTEVLVGESVTLECSATGHPPPRISWTRGDRTPLPVDPRVNITPS 411
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
GGL+ G D+G Y C ATN+ + + A + V L +F + P+ + +G
Sbjct: 412 GGLYIQNVVQG----DSGEYACSATNNIDSVHA-TAFIIVQAL-PQFTVTPQDRVVIEGQ 465
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIA 182
TV +C +G+P P + W K G L D R HLV G L I D G+Y+C A
Sbjct: 466 TVDFQC-EAKGNPPPVIAWTKGGSQLSVD---RRHLVLSSGTLRISGVALHDQGQYECQA 521
Query: 183 RNAAGTRE-SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
N G+++ A T++ + P + P D + G++V C G+P P + W + G
Sbjct: 522 VNIIGSQKVVAHLTVQPRVTPVFASIPSDTTVEVGANVQLPCSSQGEPEPAITWNKD-GV 580
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
G+ + +G L +++V AD G Y C A N++G+ S S L+V P
Sbjct: 581 QVTESGKFHISPEGFLTINDVGPADAGRYECVARNTIGSASVSMVLSVNVP 631
Score = 107 bits (258), Expect = 2e-22
Identities = 82/295 (27%), Positives = 126/295 (42%), Gaps = 19/295 (6%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRL 259
+P + + P+D +G++V F CR G+P P+++W R+ +M R+ +LDDG+L +
Sbjct: 262 RPRITSEPQDADVTSGNTVYFTCRAEGNPKPEIIWLRNNNELSMKTDSRLNLLDDGTLMI 321
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVY--DP--PSINLSPNSVNVESGNVARFTCT 315
N D+G Y C A+N G V Y P P+ + P + V G C+
Sbjct: 322 QNTQETDQGIYQCMAKNVAGEVKTQEVTLRYFGSPARPTFVIQPQNTEVLVGESVTLECS 381
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
ATG P P + W+ G+RT + P R + G+ + + D + CSA
Sbjct: 382 ATGHPPPRISWT-RGDRTPL-PVDPRVNITPSG---GLYIQNVVQGDSGE----YACSAT 432
Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
N S + V + P T P ++ + F C A P P+IAW G
Sbjct: 433 NNIDSVHATAFIIVQA-----LPQFTVTPQDRVVIEGQTVDFQCEAKGNPPPVIAWTKGG 487
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
L + R V + GTL + + D G Y C A + G L V + P
Sbjct: 488 SQLSVDRRHLVLSSGTLRISGVALHDQGQYECQAVNIIGSQKVVAHLTVQPRVTP 542
>AF040991-1|AAC39576.1| 285|Homo sapiens roundabout 2 protein.
Length = 285
Score = 179 bits (435), Expect = 6e-44
Identities = 106/290 (36%), Positives = 146/290 (50%), Gaps = 17/290 (5%)
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V G F C G P+P +FW EG++ ++FP + +V LTI + +
Sbjct: 3 VAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSV-SPTGDLTITNIQR 61
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSD-DDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
+D+ +C A+ AGS + +L VT DRPPPII GP+NQTL + A+ C A
Sbjct: 62 SDA-GYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKAT 120
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P+I+W EG ++ R + GTL +K+L SD+GTYTCVA+S G+ WS
Sbjct: 121 GDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGEASWSAV 180
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
L V + D+S LPGPP+KP +VT SVTLSW Q G+ Y +E
Sbjct: 181 LDV---TESGATISKNYDLSDLPGPPSKPQVTDVTKNSVTLSW-QPGTPGTLPASAYIIE 236
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTEN 591
FS+ S W +A V T Y V+ L P Y+F+VR N
Sbjct: 237 AFSQSV---------SNSWQTVANHVKTTLYTVRGLRPNTIYLFMVRAIN 277
Score = 87.4 bits (207), Expect = 3e-16
Identities = 56/181 (30%), Positives = 88/181 (48%), Gaps = 12/181 (6%)
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNG-QTLLFDG-----DSRMHLVDGGNLVIQDARQT 173
AQG TV C +G+P+P V+W+K G Q LLF +SR + G+L I + +++
Sbjct: 4 AQGRTVTFPC-ETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQRS 62
Query: 174 DAGRYQCIARNAAGT-----RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
DAG Y C A AG+ + L P ++ GP + + +C+ GD
Sbjct: 63 DAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKATGD 122
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
PLP + W + R + + G+L++ N+ ++D G Y+C A +S G S S L
Sbjct: 123 PLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSGEASWSAVLD 182
Query: 289 V 289
V
Sbjct: 183 V 183
Score = 69.7 bits (163), Expect = 6e-11
Identities = 63/194 (32%), Positives = 84/194 (43%), Gaps = 25/194 (12%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM--------PLGRVKVLDDGSLRLDNV 262
+VAQ G +VTF C G+P P V W++ G N+ P R V G L + N+
Sbjct: 2 IVAQ-GRTVTFPCETKGNPQPAVFWQKE-GSQNLLFPNQPQQPNSRCSVSPTGDLTITNI 59
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTA 316
+D G Y C+A G++ A L V D PP I P + + A C A
Sbjct: 60 QRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKCKA 119
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
TG P P + W EG FPG RD AT G L I + +D+ T C A +
Sbjct: 120 TGDPLPVISWLKEG---FTFPG--RDP-RATIQEQG--TLQIKNLRISDT-GTYTCVATS 170
Query: 377 YAGSSFVRGKLTVT 390
+G + L VT
Sbjct: 171 SSGEASWSAVLDVT 184
Score = 61.7 bits (143), Expect = 2e-08
Identities = 55/179 (30%), Positives = 82/179 (45%), Gaps = 22/179 (12%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHR-----SILPAGGLFFLRATHG 74
VA+ + T C G+P PA+ W K G +L + + S+ P G L
Sbjct: 3 VAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDLTITNIQ-- 60
Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREE----FRLEPESKQSAQGDTVVLEC 129
SDAG Y C+A G+ ++ A L V VL + P ++ A T +L+C
Sbjct: 61 --RSDAGYYICQALTVAGSILAK-AQLEVTDVLTDRPPPIILQGPANQTLAVDGTALLKC 117
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
G P P + W K G T F G D R + + G L I++ R +D G Y C+A +++G
Sbjct: 118 -KATGDPLPVISWLKEGFT--FPGRDPRATIQEQGTLQIKNLRISDTGTYTCVATSSSG 173
Score = 52.4 bits (120), Expect = 9e-06
Identities = 36/100 (36%), Positives = 49/100 (49%), Gaps = 4/100 (4%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D +T P I++ P + T+A A L C+A G P P I W K G R+ +
Sbjct: 88 DVLTDRPPPIILQGPANQTLAVDGTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQE 147
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
G L+ + R+ SD G Y C AT+S G A S +A L V
Sbjct: 148 QGT--LQIKNLRI-SDTGTYTCVATSSSGEA-SWSAVLDV 183
>AY090737-1|AAM00025.1| 1026|Homo sapiens contactin 4 protein.
Length = 1026
Score = 178 bits (434), Expect = 9e-44
Identities = 145/505 (28%), Positives = 219/505 (43%), Gaps = 42/505 (8%)
Query: 1 MSDDYVTSGEAPYIIEQPLDVTV---ARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH 57
++DD G P I++P V + + LNC G+P P IRW G V +
Sbjct: 17 LADDSTLHG--PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMD 74
Query: 58 -RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116
R + G L + DAG Y C ATNS+GT SR A L A L + F+ S
Sbjct: 75 FRYSVVEGSLLI---NNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYL-DNFKTRTRS 130
Query: 117 KQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
S + G +VL C PP S E + W N + + + R + GNL I ++D
Sbjct: 131 TVSVRRGQGMVLLCGPPPHSGELSYAWIFN-EYPSYQDNRRFVSQETGNLYIAKVEKSDV 189
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITG----------PEDVVAQTGSSVTFQCRV 225
G Y C+ N + + ++ + G PE V G++V +C
Sbjct: 190 GNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFA 249
Query: 226 GGDPLPDVLWRRSAGGGNMPLGRV--KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
G+P+P ++WRR+ G P+ R + +G L + N D G Y C AENS G A
Sbjct: 250 LGNPVPTIIWRRADG---KPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVA 306
Query: 284 SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
G LT Y P+ N ++V + C A GRP+PT W G P ++RD+
Sbjct: 307 RGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGE-----PLLTRDR 361
Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403
+T++ ++D C A N G F +L+V + P
Sbjct: 362 IQIEQGTLNITIVNLSDAGMYQ------CLAENKHGVIFSNAELSVIAVG---PDFSRTL 412
Query: 404 PSNQTL-PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDS 462
TL + V C +P+P+ W + L +N R ++ DG L + ++ KSD+
Sbjct: 413 LKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDA 472
Query: 463 GTYTCVASSRHGKYVWSGALLVDSP 487
G+YTC+A++ G +G L+V P
Sbjct: 473 GSYTCIATNHFGTASSTGNLVVKDP 497
Score = 143 bits (347), Expect = 3e-33
Identities = 188/737 (25%), Positives = 304/737 (41%), Gaps = 89/737 (12%)
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
PE+ +A+G TV LEC G+P P + W++ +G+ + +R H G L I + +Q
Sbjct: 232 PETVPTAKGATVKLECFA-LGNPVPTIIWRRADGKPIA--RKARRHK-SNGILEIPNFQQ 287
Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
DAG Y+C+A N+ G + A L + +P I D+ +V ++C+ G P P
Sbjct: 288 EDAGLYECVAENSRG-KNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPT 346
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-- 290
W ++ G + R+++ + G+L + V L+D G Y C AEN G + ++ L+V
Sbjct: 347 YKWLKN-GEPLLTRDRIQI-EQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAV 404
Query: 291 DPP-SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P S L V+ G C P+P W + R I+ ++ T
Sbjct: 405 GPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTW--KKGRDIL-----KENERITIS 457
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
DG L I + K+D+ + C A N+ G++ G L V + P + PS+ +
Sbjct: 458 EDGN--LRIINVTKSDA-GSYTCIATNHFGTASSTGNLVV-----KDPTRVMVPPSSMDV 509
Query: 410 PIKSMAVFPC--TAICTPEPIIAWYFEGEALI----QNHRRNVTND---GTLVLKDLDKS 460
+ V PC T + + + W F G + +H V G L+++++
Sbjct: 510 TVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLK 569
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV 520
+G Y C+ + + + L+V P PGPP +TDT+
Sbjct: 570 HAGKYVCMVQTSVDRLSAAADLIVRGP----------------PGPPEAVTIDEITDTTA 613
Query: 521 TLSWSQNNKIGSSSILGYQVEV---FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSL 577
LSW + S I Y ++ FS + + P G A V L
Sbjct: 614 QLSW-RPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTA--------TVVGL 664
Query: 578 IPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVE 637
P + Y F N G+ PS S+ +L E T + S + +V
Sbjct: 665 NPWVEYEFRTVAANVIGIGEPSRPSEKRRT---EEALPEVTPANVSGGGGSK---SELVI 718
Query: 638 LIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSG--FEIT 695
E P + + + F Y+ + FRP + M T+L S D S F
Sbjct: 719 TWETVPEELQNGR------GFGYV----VAFRPYGKM---IWMLTVLASADASRYVFRNE 765
Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755
S+ ++ +E + F K EG S + V + ++ P PP +I L+ T + + W+ P
Sbjct: 766 SVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASP 825
Query: 756 ELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815
L+ G I GY V W ++ I T +Q TS +TNL V Y + + A
Sbjct: 826 -LEKNRGRIQGYEVKY-WRHEDKEENARKIRTVGNQ-TSTKITNLKGSVLYHLAVKAYNS 882
Query: 816 IGLGPFSQKVYFNIDSR 832
G GP S V N+ +R
Sbjct: 883 AGTGPSSATV--NVTTR 897
Score = 109 bits (263), Expect = 4e-23
Identities = 96/321 (29%), Positives = 144/321 (44%), Gaps = 25/321 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I++ D+ VA + C+A G P P +W K G ++ T I G +
Sbjct: 316 PNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLL--TRDRIQIEQGTLNITI 373
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVVLEC 129
+ SDAG+Y C A N +G S NA L V + +F L G VV+EC
Sbjct: 374 VN---LSDAGMYQCLAENKHGVIFS-NAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIEC 429
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
P+ SP+P WKK G+ +L + + R+ + + GNL I + ++DAG Y CIA N GT
Sbjct: 430 -KPKASPKPVYTWKK-GRDILKENE-RITISEDGNLRIINVTKSDAGSYTCIATNHFGTA 486
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR- 248
S L + ++ P + G S+ C+V D D+++ S G + R
Sbjct: 487 SST-GNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRD 545
Query: 249 ------VKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
V D G L + N+ L G+Y C + SV +SA+ L V PP P +
Sbjct: 546 GDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPG---PPEA 602
Query: 302 VNVESGNVARFTCTATGRPEP 322
V ++ + T + RP P
Sbjct: 603 VTID--EITDTTAQLSWRPGP 621
Score = 108 bits (260), Expect = 1e-22
Identities = 93/321 (28%), Positives = 141/321 (43%), Gaps = 16/321 (4%)
Query: 1 MSDDYVTSGEAPYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59
+ +D V P I ++ P V A+ L C A G+P P I W + ++ R
Sbjct: 214 LRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARR 273
Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
G L + + DAG+Y C A NS G +R A + + +
Sbjct: 274 HKSNG---ILEIPNFQ-QEDAGLYECVAENSRGKNVARGQLTFYA--QPNWIQKINDIHV 327
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
A + V EC G P+P W KNG+ LL R+ ++ G L I +DAG YQ
Sbjct: 328 AMEENVFWEC-KANGRPKPTYKWLKNGEPLLTR--DRIQ-IEQGTLNITIVNLSDAGMYQ 383
Query: 180 CIARNAAGTRESAIATLKIHIKP-YLITGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRR 237
C+A N G S I + P + T + V + + G V +C+ P P W++
Sbjct: 384 CLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKK 443
Query: 238 SAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
G + R+ + +DG+LR+ NV +D G Y+C A N G S++G L V DP +
Sbjct: 444 --GRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVM 501
Query: 297 LSPNSVNVESGNVARFTCTAT 317
+ P+S++V G C T
Sbjct: 502 VPPSSMDVTVGESIVLPCQVT 522
Score = 99 bits (238), Expect = 5e-20
Identities = 105/414 (25%), Positives = 174/414 (42%), Gaps = 46/414 (11%)
Query: 98 NATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
++TLH + +E F L+ E K+ V L C +G+P+P++ WK NG +
Sbjct: 20 DSTLHGPIFIQEPSPVMFPLDSEEKK------VKLNC-EVKGNPKPHIRWKLNGTDVDTG 72
Query: 153 GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDV 211
D R +V+G L+ + DAG YQC A N+ GT S A L+ ++ + V
Sbjct: 73 MDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTV 132
Query: 212 VAQTGSSVTFQCRVGGDPLPDVL---WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
+ G + C G P L W + R + G+L + V +D G
Sbjct: 133 SVRRGQGMVLLC--GPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVG 190
Query: 269 EYSCEAENSVG-----------AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
Y+C N+V + G + Y+P P +V G + C A
Sbjct: 191 NYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFAL 250
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P PT+ W + P + + H + +G +L I + + D+ C A N
Sbjct: 251 GNPVPTIIWRRADGK----PIARKARRHKS---NG--ILEIPNFQQEDA-GLYECVAENS 300
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
G + RG+LT + + I ++ + ++ + C A P+P W GE
Sbjct: 301 RGKNVARGQLTFYAQPNWIQKI-----NDIHVAMEENVFWECKANGRPKPTYKWLKNGEP 355
Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
L+ R + GTL + ++ SD+G Y C+A ++HG ++S A L + P+
Sbjct: 356 LLTRDRIQI-EQGTLNITIVNLSDAGMYQCLAENKHG-VIFSNAELSVIAVGPD 407
Score = 35.9 bits (79), Expect = 0.88
Identities = 34/169 (20%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
+ P +P + A + + P P +++ T + + W+ + I GY+V+ +
Sbjct: 785 EGPFSPTTVVYSAEEEPTKP--PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWR 842
Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604
E N + G +QT + +L + Y V+ NS G +GPS + +
Sbjct: 843 HEDKEENARKIRTVG--------NQTSTKITNLKGSVLYHLAVKAYNSAG-TGPSSATVN 893
Query: 605 VTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW 653
VT S G + NS++ + + D + L + + + W
Sbjct: 894 VTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRW 942
>AF549455-1|AAP05786.1| 1026|Homo sapiens BIG-2 protein.
Length = 1026
Score = 178 bits (434), Expect = 9e-44
Identities = 145/505 (28%), Positives = 219/505 (43%), Gaps = 42/505 (8%)
Query: 1 MSDDYVTSGEAPYIIEQPLDVTV---ARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH 57
++DD G P I++P V + + LNC G+P P IRW G V +
Sbjct: 17 LADDSTLHG--PIFIQEPSPVMFPLDSEEKKVKLNCEVKGNPKPHIRWKLNGTDVDTGMD 74
Query: 58 -RSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116
R + G L + DAG Y C ATNS+GT SR A L A L + F+ S
Sbjct: 75 FRYSVVEGSLLI---NNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYL-DNFKTRTRS 130
Query: 117 KQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
S + G +VL C PP S E + W N + + + R + GNL I ++D
Sbjct: 131 TVSVRRGQGMVLLCGPPPHSGELSYAWIFN-EYPSYQDNRRFVSQETGNLYIAKVEKSDV 189
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITG----------PEDVVAQTGSSVTFQCRV 225
G Y C+ N + + ++ + G PE V G++V +C
Sbjct: 190 GNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFA 249
Query: 226 GGDPLPDVLWRRSAGGGNMPLGRV--KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
G+P+P ++WRR+ G P+ R + +G L + N D G Y C AENS G A
Sbjct: 250 LGNPVPTIIWRRADG---KPIARKARRHKSNGILEIPNFQQEDAGLYECVAENSRGKNVA 306
Query: 284 SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
G LT Y P+ N ++V + C A GRP+PT W G P ++RD+
Sbjct: 307 RGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGE-----PLLTRDR 361
Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403
+T++ ++D C A N G F +L+V + P
Sbjct: 362 IQIEQGTLNITIVNLSDAGMYQ------CLAENKHGVIFSNAELSVIAVG---PDFSRTL 412
Query: 404 PSNQTL-PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDS 462
TL + V C +P+P+ W + L +N R ++ DG L + ++ KSD+
Sbjct: 413 LKRVTLVKVGGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDA 472
Query: 463 GTYTCVASSRHGKYVWSGALLVDSP 487
G+YTC+A++ G +G L+V P
Sbjct: 473 GSYTCIATNHFGTASSTGNLVVKDP 497
Score = 143 bits (347), Expect = 3e-33
Identities = 188/737 (25%), Positives = 304/737 (41%), Gaps = 89/737 (12%)
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
PE+ +A+G TV LEC G+P P + W++ +G+ + +R H G L I + +Q
Sbjct: 232 PETVPTAKGATVKLECFA-LGNPVPTIIWRRADGKPIA--RKARRHK-SNGILEIPNFQQ 287
Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
DAG Y+C+A N+ G + A L + +P I D+ +V ++C+ G P P
Sbjct: 288 EDAGLYECVAENSRG-KNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANGRPKPT 346
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-- 290
W ++ G + R+++ + G+L + V L+D G Y C AEN G + ++ L+V
Sbjct: 347 YKWLKN-GEPLLTRDRIQI-EQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAELSVIAV 404
Query: 291 DPP-SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P S L V+ G C P+P W + R I+ ++ T
Sbjct: 405 GPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTW--KKGRDIL-----KENERITIS 457
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
DG L I + K+D+ + C A N+ G++ G L V + P + PS+ +
Sbjct: 458 EDGN--LRIINVTKSDA-GSYTCIATNHFGTASSTGNLVV-----KDPTRVMVPPSSMDV 509
Query: 410 PIKSMAVFPC--TAICTPEPIIAWYFEGEALI----QNHRRNVTND---GTLVLKDLDKS 460
+ V PC T + + + W F G + +H V G L+++++
Sbjct: 510 TVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLK 569
Query: 461 DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSV 520
+G Y C+ + + + L+V P PGPP +TDT+
Sbjct: 570 HAGKYVCMVQTSVDRLSAAADLIVRGP----------------PGPPEAVTIDEITDTTA 613
Query: 521 TLSWSQNNKIGSSSILGYQVEV---FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSL 577
LSW + S I Y ++ FS + + P G A V L
Sbjct: 614 QLSW-RPGPDNHSPITMYVIQARTPFSVGWQAVSTVPELIDGKTFTA--------TVVGL 664
Query: 578 IPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVE 637
P + Y F N G+ PS S+ +L E T + S + +V
Sbjct: 665 NPWVEYEFRTVAANVIGIGEPSRPSEKRRT---EEALPEVTPANVSGGGGSK---SELVI 718
Query: 638 LIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSG--FEIT 695
E P + + + F Y+ + FRP + M T+L S D S F
Sbjct: 719 TWETVPEELQNGR------GFGYV----VAFRPYGKM---IWMLTVLASADASRYVFRNE 765
Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755
S+ ++ +E + F K EG S + V + ++ P PP +I L+ T + + W+ P
Sbjct: 766 SVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFARSLSATDIEVFWASP 825
Query: 756 ELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815
L+ G I GY V W ++ I T +Q TS +TNL V Y + + A
Sbjct: 826 -LEKNRGRIQGYEVKY-WRHEDKEENARKIRTVGNQ-TSTKITNLKGSVLYHLAVKAYNS 882
Query: 816 IGLGPFSQKVYFNIDSR 832
G GP S V N+ +R
Sbjct: 883 AGTGPSSATV--NVTTR 897
Score = 109 bits (263), Expect = 4e-23
Identities = 96/321 (29%), Positives = 144/321 (44%), Gaps = 25/321 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I++ D+ VA + C+A G P P +W K G ++ T I G +
Sbjct: 316 PNWIQKINDIHVAMEENVFWECKANGRPKPTYKWLKNGEPLL--TRDRIQIEQGTLNITI 373
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVVLEC 129
+ SDAG+Y C A N +G S NA L V + +F L G VV+EC
Sbjct: 374 VN---LSDAGMYQCLAENKHGVIFS-NAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIEC 429
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
P+ SP+P WKK G+ +L + + R+ + + GNL I + ++DAG Y CIA N GT
Sbjct: 430 -KPKASPKPVYTWKK-GRDILKENE-RITISEDGNLRIINVTKSDAGSYTCIATNHFGTA 486
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR- 248
S L + ++ P + G S+ C+V D D+++ S G + R
Sbjct: 487 SST-GNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRD 545
Query: 249 ------VKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
V D G L + N+ L G+Y C + SV +SA+ L V PP P +
Sbjct: 546 GDHFERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPPG---PPEA 602
Query: 302 VNVESGNVARFTCTATGRPEP 322
V ++ + T + RP P
Sbjct: 603 VTID--EITDTTAQLSWRPGP 621
Score = 108 bits (260), Expect = 1e-22
Identities = 93/321 (28%), Positives = 141/321 (43%), Gaps = 16/321 (4%)
Query: 1 MSDDYVTSGEAPYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59
+ +D V P I ++ P V A+ L C A G+P P I W + ++ R
Sbjct: 214 LRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARR 273
Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
G L + + DAG+Y C A NS G +R A + + +
Sbjct: 274 HKSNG---ILEIPNFQ-QEDAGLYECVAENSRGKNVARGQLTFYA--QPNWIQKINDIHV 327
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
A + V EC G P+P W KNG+ LL R+ ++ G L I +DAG YQ
Sbjct: 328 AMEENVFWEC-KANGRPKPTYKWLKNGEPLLTR--DRIQ-IEQGTLNITIVNLSDAGMYQ 383
Query: 180 CIARNAAGTRESAIATLKIHIKP-YLITGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRR 237
C+A N G S I + P + T + V + + G V +C+ P P W++
Sbjct: 384 CLAENKHGVIFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTWKK 443
Query: 238 SAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
G + R+ + +DG+LR+ NV +D G Y+C A N G S++G L V DP +
Sbjct: 444 --GRDILKENERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVM 501
Query: 297 LSPNSVNVESGNVARFTCTAT 317
+ P+S++V G C T
Sbjct: 502 VPPSSMDVTVGESIVLPCQVT 522
Score = 99 bits (238), Expect = 5e-20
Identities = 105/414 (25%), Positives = 174/414 (42%), Gaps = 46/414 (11%)
Query: 98 NATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
++TLH + +E F L+ E K+ V L C +G+P+P++ WK NG +
Sbjct: 20 DSTLHGPIFIQEPSPVMFPLDSEEKK------VKLNC-EVKGNPKPHIRWKLNGTDVDTG 72
Query: 153 GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDV 211
D R +V+G L+ + DAG YQC A N+ GT S A L+ ++ + V
Sbjct: 73 MDFRYSVVEGSLLINNPNKTQDAGTYQCTATNSFGTIVSREAKLQFAYLDNFKTRTRSTV 132
Query: 212 VAQTGSSVTFQCRVGGDPLPDVL---WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
+ G + C G P L W + R + G+L + V +D G
Sbjct: 133 SVRRGQGMVLLC--GPPPHSGELSYAWIFNEYPSYQDNRRFVSQETGNLYIAKVEKSDVG 190
Query: 269 EYSCEAENSVG-----------AVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
Y+C N+V + G + Y+P P +V G + C A
Sbjct: 191 NYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEPKIEVQFPETVPTAKGATVKLECFAL 250
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P PT+ W + P + + H + +G +L I + + D+ C A N
Sbjct: 251 GNPVPTIIWRRADGK----PIARKARRHKS---NG--ILEIPNFQQEDA-GLYECVAENS 300
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
G + RG+LT + + I ++ + ++ + C A P+P W GE
Sbjct: 301 RGKNVARGQLTFYAQPNWIQKI-----NDIHVAMEENVFWECKANGRPKPTYKWLKNGEP 355
Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPN 491
L+ R + GTL + ++ SD+G Y C+A ++HG ++S A L + P+
Sbjct: 356 LLTRDRIQI-EQGTLNITIVNLSDAGMYQCLAENKHG-VIFSNAELSVIAVGPD 407
Score = 35.9 bits (79), Expect = 0.88
Identities = 34/169 (20%), Positives = 67/169 (39%), Gaps = 11/169 (6%)
Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
+ P +P + A + + P P +++ T + + W+ + I GY+V+ +
Sbjct: 785 EGPFSPTTVVYSAEEEPTKP--PASIFARSLSATDIEVFWASPLEKNRGRIQGYEVKYWR 842
Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604
E N + G +QT + +L + Y V+ NS G +GPS + +
Sbjct: 843 HEDKEENARKIRTVG--------NQTSTKITNLKGSVLYHLAVKAYNSAG-TGPSSATVN 893
Query: 605 VTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW 653
VT S G + NS++ + + D + L + + + W
Sbjct: 894 VTTRKPPPSQPPGNIIWNSSDSKIILNWDQVKALDNESEVKGYKVLYRW 942
>AF289030-1|AAL56711.1| 1746|Homo sapiens Down syndrome cell adhesion
molecule splice variant protein.
Length = 1746
Score = 176 bits (428), Expect = 5e-43
Identities = 210/827 (25%), Positives = 334/827 (40%), Gaps = 71/827 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I ++T + ++CR G P +I+WYK L+ + + G L
Sbjct: 256 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSD 315
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
V D G Y C + S++ +HV V F E + + G V + C+
Sbjct: 316 VQKEV--DEGEYTCNVLVQPQLSTSQS--VHVTVKVPPFIQPFEFPRFSIGQRVFIPCVV 371
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G + W+K+G+ + + +D +L I + G Y CIARN A E
Sbjct: 372 VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 431
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN---MPL- 246
+ L + + P + P D G +V C G P+P ++W+ S G G P+
Sbjct: 432 HQ-SQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIA 490
Query: 247 --GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVN 303
GR++VL +GSL + +V+ D G Y C+ N VGA VS S YLTV P I PN+
Sbjct: 491 LNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTL 550
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTD 362
G +CTA G + W E II P M+R V + V + L I T
Sbjct: 551 ATQGQKKEMSCTAHGEKPIIVRWEKEDR--IINPEMARYLVSTKEVGEEVISTLQILPTV 608
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
+ DS C A+N G +LTV D PP I +T+ ++ F +
Sbjct: 609 REDS-GFFSCHAINSYGEDRGIIQLTVQEPPD-PPEIEIKDVKARTITLRWTMGFDGNSP 666
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
T I ++V+ N T++ D+ S + + A +R GK S
Sbjct: 667 ITGYDIECKNKSDSWDSAQRTKDVSPQLNSATII--DIHPSSTYSIRMYAKNRIGKSEPS 724
Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSSILGY 538
L + AD ++ GPP + ++ S+ ++W K + + I GY
Sbjct: 725 NELTI------------TADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGY 772
Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
Q+ RE +G N N + + Y + +L Y +V+ N G +GP
Sbjct: 773 QIGY--REYSTGGNFQFNI---ISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG-TGP 826
Query: 599 SPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF 658
S T +D S + E ++A ++I + W L+
Sbjct: 827 SSQEIITTTLEDVPS--------------------YPPENVQAIATSPESISISWSTLSK 866
Query: 659 YYLEGLFIYFRPLDNITI-EYEMKTILHSNDVS-GFEITSLRKYTKYEFFLIPFYKKFEG 716
L G+ FR + + + E+ I + E+ L KYT Y ++ F + +G
Sbjct: 867 EALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDG 926
Query: 717 KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
S +T +DVP GPP ++ + + V + W PP L+L NGII Y V +
Sbjct: 927 VRSEQIFTRTKEDVP-GPPAGVKAAAASASMVFVSWLPP-LKL-NGIIRKYTVFCS---- 979
Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
++++ + S + NL+ YSV + A T G G S+
Sbjct: 980 HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSE 1026
Score = 142 bits (344), Expect = 7e-33
Identities = 197/841 (23%), Positives = 329/841 (39%), Gaps = 92/841 (10%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHR---SILPAGGLF 67
P II + V+ +P +L C G+P P I W ++ +HR I G +
Sbjct: 159 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 218
Query: 68 -FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125
+L + +V D GVY C A NS G + A ++V R + P +A G
Sbjct: 219 SYLNISSSQVR-DGGVYRCTANNSAGVVLYQ-ARINV---RGPASIRPMKNITAIAGRDT 273
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQC--IA 182
+ C G P ++ W KN L F+ ++ + G L + D ++ D G Y C +
Sbjct: 274 YIHCRVI-GYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGEYTCNVLV 331
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGG 241
+ T +S T+K+ P I E G V C V LP + W++
Sbjct: 332 QPQLSTSQSVHVTVKV---PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRP 388
Query: 242 GNMPLG-RVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
LG + +D SLR+ N+ L G Y+C A N AV L V PP + P
Sbjct: 389 IPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 448
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ G C+A G P PT+ W + P + L I
Sbjct: 449 RDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGV--PQFQPIALNGRIQVLSNGSLLIK 506
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ DS +C N G+ + LTV + P +IT+ P+
Sbjct: 507 HVVEEDS-GYYLCKVSNDVGADVSKSMYLTV-----KIPAMITSYPNTTLATQGQKKEMS 560
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTND--------GTLVLKDLDKSDSGTYTCVAS 470
CTA I+ W E + R + + TL + + DSG ++C A
Sbjct: 561 CTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAI 620
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+ +G+ L V P P PP I +V ++TL W+
Sbjct: 621 NSYGEDRGIIQLTVQEP----------------PDPPEIEI-KDVKARTITLRWTMGFD- 662
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G+S I GY +E ++ S ++ R ++ +++ + + P TY + +
Sbjct: 663 GNSPITGYDIECKNKSD-SWDSAQRTKD----VSPQLNSA--TIIDIHPSSTYSIRMYAK 715
Query: 591 NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650
N G S P S+ +T+ D + D + + PI S++I+
Sbjct: 716 NRIGKSEP---SNELTITADEAA------------------PDGPPQEVHLEPISSQSIR 754
Query: 651 LMWEI----LNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705
+ W+ L + G I +R ++ + ++ S D + + +L K+T+Y
Sbjct: 755 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 814
Query: 706 FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
+ + G S + TL+DVP PP N++ + ++ + WS + NGI+
Sbjct: 815 VVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQ 874
Query: 766 GYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
G+ V+ W ++ + N T Q SL + L +YS+Q+ A T G G S+++
Sbjct: 875 GFRVIY-WANLMDGELGEIKNITTTQ-PSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQI 932
Query: 826 Y 826
+
Sbjct: 933 F 933
Score = 103 bits (246), Expect = 5e-21
Identities = 108/464 (23%), Positives = 179/464 (38%), Gaps = 37/464 (7%)
Query: 37 GSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95
G P P RW K + L +S + + + +R SD+G Y CE +N YGTA+
Sbjct: 2 GHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRP------SDSGSYVCEVSNRYGTAK 55
Query: 96 SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
L+ + P +S+ G V L C G+ + + W +NG+ L +
Sbjct: 56 VIGRLYVKQPLKAT--ISPRKVKSSVGSQVSLSC-SVTGTEDQELSWYRNGEILNPGKNV 112
Query: 156 RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215
R+ ++ NL++ ++D G YQC R + + + + P +I+ + V
Sbjct: 113 RITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSP 172
Query: 216 GSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGS----LRLDNVILADE 267
V+ C V G PLP + W GG+ + ++ + +G+ L + + + D
Sbjct: 173 AEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQM-ITSEGNVVSYLNISSSQVRDG 231
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
G Y C A NS G V + V P SI N + +G C G P ++ W
Sbjct: 232 GVYRCTANNSAGVVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVIGYPYYSIKWY 290
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
N + P H F+ L ++D K C+ + S +
Sbjct: 291 KNSN---LLP-----FNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLS-TSQSV 341
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRNV 446
VT + PP I + I PC + PI I W +G + + +
Sbjct: 342 HVTV---KVPPFIQPFEFPR-FSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTI 397
Query: 447 TN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
N +L + +L +G YTC+A + L+V P
Sbjct: 398 DNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 441
Score = 89.4 bits (212), Expect = 7e-17
Identities = 119/488 (24%), Positives = 201/488 (41%), Gaps = 52/488 (10%)
Query: 15 IEQPLDVTVARHQ-------PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
++QPL T++ + +L+C G+ + WY+ G ++ + +++ G
Sbjct: 62 VKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEIL--NPGKNVRITGINH 119
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES----KQSAQGD 123
V SD G Y C +A+ +V V+ E+ + S K + +
Sbjct: 120 ENLIMDHMVKSDGGAYQCFVRKDKLSAQD-----YVQVVLEDGTPKIISAFSEKVVSPAE 174
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH--LVDGGNLV----IQDARQTDAGR 177
V L C +G+P P + W + +L G R+ + GN+V I ++ D G
Sbjct: 175 PVSLMC-NVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGV 233
Query: 178 YQCIARNAAGTRESAIATLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
Y+C A N+AG + +I+++ P I +++ A G CRV G P + W
Sbjct: 234 YRCTANNSAGV---VLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWY 290
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVIL-ADEGEYSCEA-ENSVGAVSASGYLTVYDPPS 294
+++ +V ++G+L+L +V DEGEY+C + S S ++TV PP
Sbjct: 291 KNSNLLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPF 350
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
I G C P T+ W +G G++ D D
Sbjct: 351 IQ-PFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDN------IDFT 403
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
+ L I++ + N C A N A + + +L V R PP P +Q
Sbjct: 404 SSLRISNLSLMHNGN-YTCIARNEAAAVEHQSQLIV-----RVPPKFVVQPRDQDGIYGK 457
Query: 414 MAVFPCTAICTPEPIIAWYF-EGEALIQ------NHRRNVTNDGTLVLKDLDKSDSGTYT 466
+ C+A P P I W F +G + Q N R V ++G+L++K + + DSG Y
Sbjct: 458 AVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVEEDSGYYL 517
Query: 467 CVASSRHG 474
C S+ G
Sbjct: 518 CKVSNDVG 525
Score = 56.4 bits (130), Expect = 6e-07
Identities = 59/241 (24%), Positives = 104/241 (43%), Gaps = 33/241 (13%)
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
AV AG +TV P I+T T P V PC A+ P P + W
Sbjct: 1015 AVTSAGRGNSSEIITVEPLAKAPARILTFS-GTVTTPWMKDIVLPCKAVGDPSPAVKWMK 1073
Query: 434 EGE---ALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
+ +L+ + RR++ ++G+ +++ + DSG Y+C+A++ G S ++++
Sbjct: 1074 DSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWG----SDEIILN---- 1125
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
V P P ++ T +S+TLSW + G SSI GY ++ +S +
Sbjct: 1126 --------LQVQVPPDQPRLTVS-KTTSSSITLSWLPGDN-GGSSIRGYILQ-YSED--- 1171
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
NS W + Y +++L G Y F + +N G S + ++ T+G
Sbjct: 1172 ------NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGK 1225
Query: 610 D 610
+
Sbjct: 1226 E 1226
Score = 50.0 bits (114), Expect = 5e-05
Identities = 47/165 (28%), Positives = 73/165 (44%), Gaps = 19/165 (11%)
Query: 125 VVLECLPPRGSPEPNVYWKK--NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
+VL C G P P V W K NG L D R + G+ +I+ + D+G Y CIA
Sbjct: 1055 IVLPCKAV-GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1113
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQ-TGSSVTFQCRV---GGDPLPDVLWRRS 238
N G+ E I L++ + P P V++ T SS+T GG + + + S
Sbjct: 1114 NNNWGSDE-IILNLQVQVPP---DQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1169
Query: 239 AGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
G+ P+ + S RL+N+ +++ A+N VG
Sbjct: 1170 EDNSEQWGSFPISP----SERSYRLENLKCGTWYKFTLTAQNGVG 1210
Score = 44.4 bits (100), Expect = 0.003
Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 8/77 (10%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGLFFLRATHGRV 76
VT + L C+A G PSPA++W K LV D RSI + G F +R
Sbjct: 1047 VTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIF-SNGSFIIRTVKA-- 1103
Query: 77 HSDAGVYWCEATNSYGT 93
D+G Y C A N++G+
Sbjct: 1104 -EDSGYYSCIANNNWGS 1119
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
+ C+ GDP P V W + + G + GR + +GS + V D G YSC A
Sbjct: 1055 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1114
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G+ L V PP
Sbjct: 1115 NNWGSDEIILNLQVQVPP 1132
Score = 42.3 bits (95), Expect = 0.010
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 6/107 (5%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
PEP W + L + R T G L+++++ SDSG+Y C S+R+G G L V
Sbjct: 4 PEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 62
Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKI 530
P+ I V S G ++ +VT T LSW +N +I
Sbjct: 63 KQPLKATI---SPRKVKSSVGSQVS-LSCSVTGTEDQELSWYRNGEI 105
>AF217525-1|AAF27525.1| 2012|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 2012
Score = 176 bits (428), Expect = 5e-43
Identities = 210/827 (25%), Positives = 334/827 (40%), Gaps = 71/827 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I ++T + ++CR G P +I+WYK L+ + + G L
Sbjct: 504 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSD 563
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
V D G Y C + S++ +HV V F E + + G V + C+
Sbjct: 564 VQKEV--DEGEYTCNVLVQPQLSTSQS--VHVTVKVPPFIQPFEFPRFSIGQRVFIPCVV 619
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G + W+K+G+ + + +D +L I + G Y CIARN A E
Sbjct: 620 VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 679
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN---MPL- 246
+ L + + P + P D G +V C G P+P ++W+ S G G P+
Sbjct: 680 HQ-SQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIA 738
Query: 247 --GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVN 303
GR++VL +GSL + +V+ D G Y C+ N VGA VS S YLTV P I PN+
Sbjct: 739 LNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTL 798
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTD 362
G +CTA G + W E II P M+R V + V + L I T
Sbjct: 799 ATQGQKKEMSCTAHGEKPIIVRWEKEDR--IINPEMARYLVSTKEVGEEVISTLQILPTV 856
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
+ DS C A+N G +LTV D PP I +T+ ++ F +
Sbjct: 857 REDS-GFFSCHAINSYGEDRGIIQLTVQEPPD-PPEIEIKDVKARTITLRWTMGFDGNSP 914
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
T I ++V+ N T++ D+ S + + A +R GK S
Sbjct: 915 ITGYDIECKNKSDSWDSAQRTKDVSPQLNSATII--DIHPSSTYSIRMYAKNRIGKSEPS 972
Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSSILGY 538
L + AD ++ GPP + ++ S+ ++W K + + I GY
Sbjct: 973 NELTI------------TADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGY 1020
Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
Q+ RE +G N N + + Y + +L Y +V+ N G +GP
Sbjct: 1021 QIGY--REYSTGGNFQFNI---ISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG-TGP 1074
Query: 599 SPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF 658
S T +D S + E ++A ++I + W L+
Sbjct: 1075 SSQEIITTTLEDVPS--------------------YPPENVQAIATSPESISISWSTLSK 1114
Query: 659 YYLEGLFIYFRPLDNITI-EYEMKTILHSNDVS-GFEITSLRKYTKYEFFLIPFYKKFEG 716
L G+ FR + + + E+ I + E+ L KYT Y ++ F + +G
Sbjct: 1115 EALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDG 1174
Query: 717 KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
S +T +DVP GPP ++ + + V + W PP L+L NGII Y V +
Sbjct: 1175 VRSEQIFTRTKEDVP-GPPAGVKAAAASASMVFVSWLPP-LKL-NGIIRKYTVFCS---- 1227
Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
++++ + S + NL+ YSV + A T G G S+
Sbjct: 1228 HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSE 1274
Score = 142 bits (344), Expect = 7e-33
Identities = 197/841 (23%), Positives = 329/841 (39%), Gaps = 92/841 (10%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHR---SILPAGGLF 67
P II + V+ +P +L C G+P P I W ++ +HR I G +
Sbjct: 407 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 466
Query: 68 -FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125
+L + +V D GVY C A NS G + A ++V R + P +A G
Sbjct: 467 SYLNISSSQVR-DGGVYRCTANNSAGVVLYQ-ARINV---RGPASIRPMKNITAIAGRDT 521
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQC--IA 182
+ C G P ++ W KN L F+ ++ + G L + D ++ D G Y C +
Sbjct: 522 YIHCRVI-GYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGEYTCNVLV 579
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGG 241
+ T +S T+K+ P I E G V C V LP + W++
Sbjct: 580 QPQLSTSQSVHVTVKV---PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRP 636
Query: 242 GNMPLG-RVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
LG + +D SLR+ N+ L G Y+C A N AV L V PP + P
Sbjct: 637 IPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 696
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ G C+A G P PT+ W + P + L I
Sbjct: 697 RDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGV--PQFQPIALNGRIQVLSNGSLLIK 754
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ DS +C N G+ + LTV + P +IT+ P+
Sbjct: 755 HVVEEDS-GYYLCKVSNDVGADVSKSMYLTV-----KIPAMITSYPNTTLATQGQKKEMS 808
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTND--------GTLVLKDLDKSDSGTYTCVAS 470
CTA I+ W E + R + + TL + + DSG ++C A
Sbjct: 809 CTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAI 868
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+ +G+ L V P P PP I +V ++TL W+
Sbjct: 869 NSYGEDRGIIQLTVQEP----------------PDPPEIEI-KDVKARTITLRWTMGFD- 910
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G+S I GY +E ++ S ++ R ++ +++ + + P TY + +
Sbjct: 911 GNSPITGYDIECKNKSD-SWDSAQRTKD----VSPQLNSA--TIIDIHPSSTYSIRMYAK 963
Query: 591 NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650
N G S P S+ +T+ D + D + + PI S++I+
Sbjct: 964 NRIGKSEP---SNELTITADEAA------------------PDGPPQEVHLEPISSQSIR 1002
Query: 651 LMWEI----LNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705
+ W+ L + G I +R ++ + ++ S D + + +L K+T+Y
Sbjct: 1003 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 1062
Query: 706 FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
+ + G S + TL+DVP PP N++ + ++ + WS + NGI+
Sbjct: 1063 VVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQ 1122
Query: 766 GYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
G+ V+ W ++ + N T Q SL + L +YS+Q+ A T G G S+++
Sbjct: 1123 GFRVIY-WANLMDGELGEIKNITTTQ-PSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQI 1180
Query: 826 Y 826
+
Sbjct: 1181 F 1181
Score = 124 bits (299), Expect = 2e-27
Identities = 126/501 (25%), Positives = 208/501 (41%), Gaps = 47/501 (9%)
Query: 13 YIIEQPLDVTVARHQPATL-NCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGLF-- 67
Y + L V TL C A G P +RWY + D R + P G L
Sbjct: 25 YFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIF 84
Query: 68 -FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
F ++ + D Y+C A N G RS++ + AVLRE + + E +++ +G+ V
Sbjct: 85 PFPPSSFSTLIHD-NTYYCTAENPSGKIRSQDVHIK-AVLREPYTVRVEDQKTMRGNVAV 142
Query: 127 LECLPPRGSPE--PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIAR 183
+C+ P V W+K+ +L+ SR + G L I+D + D Y+CI R
Sbjct: 143 FKCIIPSSVEAYITVVSWEKDTVSLV--SGSRFLITSTGALYIKDVQNEDGLYNYRCITR 200
Query: 184 N--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+ TR+S A L + + P ++ G + A G V C+ G P PD W +
Sbjct: 201 HRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLK 260
Query: 238 SAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
NMPL GR + G L ++N+ +D G Y CE N G G L V P
Sbjct: 261 D----NMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLK 315
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+SP V G+ +C+ TG + + W G I+ PG + T + +
Sbjct: 316 ATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGE--ILNPGKN---VRITGI-NHEN 369
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
++ + + + +V+ L +D P II+ P + +
Sbjct: 370 LIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVL-----EDGTPKIISAFSEKVVSPAEPV 424
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQ--NHR--RNVTNDGTLV----LKDLDKSDSGTYT 466
++ C TP P I W + + +++ +HR + +T++G +V + D G Y
Sbjct: 425 SLM-CNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 483
Query: 467 CVASSRHGKYVWSGALLVDSP 487
C A++ G ++ + V P
Sbjct: 484 CTANNSAGVVLYQARINVRGP 504
Score = 109 bits (261), Expect = 8e-23
Identities = 112/474 (23%), Positives = 184/474 (38%), Gaps = 37/474 (7%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
Q L C+A G P P RW K + L +S + + + +R SD+G Y C
Sbjct: 240 QRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRP------SDSGSYVC 293
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
E +N YGTA+ L+ + P +S+ G V L C G+ + + W +N
Sbjct: 294 EVSNRYGTAKVIGRLYVKQPLKAT--ISPRKVKSSVGSQVSLSC-SVTGTEDQELSWYRN 350
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G+ L + R+ ++ NL++ ++D G YQC R + + + + P +I
Sbjct: 351 GEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKII 410
Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGS----L 257
+ + V V+ C V G PLP + W GG+ + ++ + +G+ L
Sbjct: 411 SAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQM-ITSEGNVVSYL 469
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ + + D G Y C A NS G V + V P SI N + +G C
Sbjct: 470 NISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVI 528
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P ++ W N + P H F+ L ++D K C+ +
Sbjct: 529 GYPYYSIKWYKNSN---LLP-----FNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQ 580
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGE 436
S + VT + PP I + I PC + PI I W +G
Sbjct: 581 PQLS-TSQSVHVTV---KVPPFIQPFEFPR-FSIGQRVFIPCVVVSGDLPITITWQKDGR 635
Query: 437 ALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ + + N +L + +L +G YTC+A + L+V P
Sbjct: 636 PIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 689
Score = 57.6 bits (133), Expect = 3e-07
Identities = 83/349 (23%), Positives = 130/349 (37%), Gaps = 31/349 (8%)
Query: 198 IHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDDG 255
+H Y + ++VV + + C G P + W + G + ++ V +G
Sbjct: 20 LHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNG 79
Query: 256 SLRL------DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--- 306
+L++ L + Y C AEN G + + ++ P +V VE
Sbjct: 80 TLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHI----KAVLREPYTVRVEDQKT 135
Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
GNVA F C E + T+ SR +T L I D
Sbjct: 136 MRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGA------LYIKDVQNE 189
Query: 365 DSRNTIVC-SAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D C + Y G + + SD P I +G ++ PC A+
Sbjct: 190 DGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKAL 249
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
PEP W + L + R T G L+++++ SDSG+Y C S+R+G G L
Sbjct: 250 GHPEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSNRYGTAKVIGRL 308
Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKI 530
V P+ I V S G ++ +VT T LSW +N +I
Sbjct: 309 YVKQPLKATI---SPRKVKSSVGSQVS-LSCSVTGTEDQELSWYRNGEI 353
Score = 56.4 bits (130), Expect = 6e-07
Identities = 59/241 (24%), Positives = 104/241 (43%), Gaps = 33/241 (13%)
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
AV AG +TV P I+T T P V PC A+ P P + W
Sbjct: 1263 AVTSAGRGNSSEIITVEPLAKAPARILTFS-GTVTTPWMKDIVLPCKAVGDPSPAVKWMK 1321
Query: 434 EGE---ALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
+ +L+ + RR++ ++G+ +++ + DSG Y+C+A++ G S ++++
Sbjct: 1322 DSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWG----SDEIILN---- 1373
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
V P P ++ T +S+TLSW + G SSI GY ++ +S +
Sbjct: 1374 --------LQVQVPPDQPRLTVS-KTTSSSITLSWLPGDN-GGSSIRGYILQ-YSED--- 1419
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
NS W + Y +++L G Y F + +N G S + ++ T+G
Sbjct: 1420 ------NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGK 1473
Query: 610 D 610
+
Sbjct: 1474 E 1474
Score = 50.0 bits (114), Expect = 5e-05
Identities = 47/165 (28%), Positives = 73/165 (44%), Gaps = 19/165 (11%)
Query: 125 VVLECLPPRGSPEPNVYWKK--NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
+VL C G P P V W K NG L D R + G+ +I+ + D+G Y CIA
Sbjct: 1303 IVLPCKAV-GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1361
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQ-TGSSVTFQCRV---GGDPLPDVLWRRS 238
N G+ E I L++ + P P V++ T SS+T GG + + + S
Sbjct: 1362 NNNWGSDE-IILNLQVQVPP---DQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1417
Query: 239 AGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
G+ P+ + S RL+N+ +++ A+N VG
Sbjct: 1418 EDNSEQWGSFPISP----SERSYRLENLKCGTWYKFTLTAQNGVG 1458
Score = 44.4 bits (100), Expect = 0.003
Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 8/77 (10%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGLFFLRATHGRV 76
VT + L C+A G PSPA++W K LV D RSI + G F +R
Sbjct: 1295 VTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIF-SNGSFIIRTVKA-- 1351
Query: 77 HSDAGVYWCEATNSYGT 93
D+G Y C A N++G+
Sbjct: 1352 -EDSGYYSCIANNNWGS 1367
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
+ C+ GDP P V W + + G + GR + +GS + V D G YSC A
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1362
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G+ L V PP
Sbjct: 1363 NNWGSDEIILNLQVQVPP 1380
>AF023450-1|AAC17967.1| 1571|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 1571
Score = 176 bits (428), Expect = 5e-43
Identities = 210/827 (25%), Positives = 334/827 (40%), Gaps = 71/827 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I ++T + ++CR G P +I+WYK L+ + + G L
Sbjct: 504 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSD 563
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
V D G Y C + S++ +HV V F E + + G V + C+
Sbjct: 564 VQKEV--DEGEYTCNVLVQPQLSTSQS--VHVTVKVPPFIQPFEFPRFSIGQRVFIPCVV 619
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G + W+K+G+ + + +D +L I + G Y CIARN A E
Sbjct: 620 VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 679
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN---MPL- 246
+ L + + P + P D G +V C G P+P ++W+ S G G P+
Sbjct: 680 HQ-SQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIA 738
Query: 247 --GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVN 303
GR++VL +GSL + +V+ D G Y C+ N VGA VS S YLTV P I PN+
Sbjct: 739 LNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTL 798
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTD 362
G +CTA G + W E II P M+R V + V + L I T
Sbjct: 799 ATQGQKKEMSCTAHGEKPIIVRWEKEDR--IINPEMARYLVSTKEVGEEVISTLQILPTV 856
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
+ DS C A+N G +LTV D PP I +T+ ++ F +
Sbjct: 857 REDS-GFFSCHAINSYGEDRGIIQLTVQEPPD-PPEIEIKDVKARTITLRWTMGFDGNSP 914
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
T I ++V+ N T++ D+ S + + A +R GK S
Sbjct: 915 ITGYDIECKNKSDSWDSAQRTKDVSPQLNSATII--DIHPSSTYSIRMYAKNRIGKSEPS 972
Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSSILGY 538
L + AD ++ GPP + ++ S+ ++W K + + I GY
Sbjct: 973 NELTI------------TADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGY 1020
Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
Q+ RE +G N N + + Y + +L Y +V+ N G +GP
Sbjct: 1021 QIGY--REYSTGGNFQFNI---ISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG-TGP 1074
Query: 599 SPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF 658
S T +D S + E ++A ++I + W L+
Sbjct: 1075 SSQEIITTTLEDVPS--------------------YPPENVQAIATSPESISISWSTLSK 1114
Query: 659 YYLEGLFIYFRPLDNITI-EYEMKTILHSNDVS-GFEITSLRKYTKYEFFLIPFYKKFEG 716
L G+ FR + + + E+ I + E+ L KYT Y ++ F + +G
Sbjct: 1115 EALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDG 1174
Query: 717 KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
S +T +DVP GPP ++ + + V + W PP L+L NGII Y V +
Sbjct: 1175 VRSEQIFTRTKEDVP-GPPAGVKAAAASASMVFVSWLPP-LKL-NGIIRKYTVFCS---- 1227
Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
++++ + S + NL+ YSV + A T G G S+
Sbjct: 1228 HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSE 1274
Score = 142 bits (344), Expect = 7e-33
Identities = 197/841 (23%), Positives = 329/841 (39%), Gaps = 92/841 (10%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHR---SILPAGGLF 67
P II + V+ +P +L C G+P P I W ++ +HR I G +
Sbjct: 407 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 466
Query: 68 -FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125
+L + +V D GVY C A NS G + A ++V R + P +A G
Sbjct: 467 SYLNISSSQVR-DGGVYRCTANNSAGVVLYQ-ARINV---RGPASIRPMKNITAIAGRDT 521
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQC--IA 182
+ C G P ++ W KN L F+ ++ + G L + D ++ D G Y C +
Sbjct: 522 YIHCRVI-GYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGEYTCNVLV 579
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGG 241
+ T +S T+K+ P I E G V C V LP + W++
Sbjct: 580 QPQLSTSQSVHVTVKV---PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRP 636
Query: 242 GNMPLG-RVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
LG + +D SLR+ N+ L G Y+C A N AV L V PP + P
Sbjct: 637 IPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 696
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ G C+A G P PT+ W + P + L I
Sbjct: 697 RDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGV--PQFQPIALNGRIQVLSNGSLLIK 754
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ DS +C N G+ + LTV + P +IT+ P+
Sbjct: 755 HVVEEDS-GYYLCKVSNDVGADVSKSMYLTV-----KIPAMITSYPNTTLATQGQKKEMS 808
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTND--------GTLVLKDLDKSDSGTYTCVAS 470
CTA I+ W E + R + + TL + + DSG ++C A
Sbjct: 809 CTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAI 868
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+ +G+ L V P P PP I +V ++TL W+
Sbjct: 869 NSYGEDRGIIQLTVQEP----------------PDPPEIEI-KDVKARTITLRWTMGFD- 910
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G+S I GY +E ++ S ++ R ++ +++ + + P TY + +
Sbjct: 911 GNSPITGYDIECKNKSD-SWDSAQRTKD----VSPQLNSA--TIIDIHPSSTYSIRMYAK 963
Query: 591 NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650
N G S P S+ +T+ D + D + + PI S++I+
Sbjct: 964 NRIGKSEP---SNELTITADEAA------------------PDGPPQEVHLEPISSQSIR 1002
Query: 651 LMWEI----LNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705
+ W+ L + G I +R ++ + ++ S D + + +L K+T+Y
Sbjct: 1003 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 1062
Query: 706 FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
+ + G S + TL+DVP PP N++ + ++ + WS + NGI+
Sbjct: 1063 VVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQ 1122
Query: 766 GYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
G+ V+ W ++ + N T Q SL + L +YS+Q+ A T G G S+++
Sbjct: 1123 GFRVIY-WANLMDGELGEIKNITTTQ-PSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQI 1180
Query: 826 Y 826
+
Sbjct: 1181 F 1181
Score = 124 bits (299), Expect = 2e-27
Identities = 126/501 (25%), Positives = 208/501 (41%), Gaps = 47/501 (9%)
Query: 13 YIIEQPLDVTVARHQPATL-NCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGLF-- 67
Y + L V TL C A G P +RWY + D R + P G L
Sbjct: 25 YFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIF 84
Query: 68 -FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
F ++ + D Y+C A N G RS++ + AVLRE + + E +++ +G+ V
Sbjct: 85 PFPPSSFSTLIHD-NTYYCTAENPSGKIRSQDVHIK-AVLREPYTVRVEDQKTMRGNVAV 142
Query: 127 LECLPPRGSPE--PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIAR 183
+C+ P V W+K+ +L+ SR + G L I+D + D Y+CI R
Sbjct: 143 FKCIIPSSVEAYITVVSWEKDTVSLV--SGSRFLITSTGALYIKDVQNEDGLYNYRCITR 200
Query: 184 N--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+ TR+S A L + + P ++ G + A G V C+ G P PD W +
Sbjct: 201 HRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLK 260
Query: 238 SAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
NMPL GR + G L ++N+ +D G Y CE N G G L V P
Sbjct: 261 D----NMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLK 315
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+SP V G+ +C+ TG + + W G I+ PG + T + +
Sbjct: 316 ATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGE--ILNPGKN---VRITGI-NHEN 369
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
++ + + + +V+ L +D P II+ P + +
Sbjct: 370 LIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVL-----EDGTPKIISAFSEKVVSPAEPV 424
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQ--NHR--RNVTNDGTLV----LKDLDKSDSGTYT 466
++ C TP P I W + + +++ +HR + +T++G +V + D G Y
Sbjct: 425 SLM-CNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 483
Query: 467 CVASSRHGKYVWSGALLVDSP 487
C A++ G ++ + V P
Sbjct: 484 CTANNSAGVVLYQARINVRGP 504
Score = 109 bits (261), Expect = 8e-23
Identities = 112/474 (23%), Positives = 184/474 (38%), Gaps = 37/474 (7%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
Q L C+A G P P RW K + L +S + + + +R SD+G Y C
Sbjct: 240 QRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRP------SDSGSYVC 293
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
E +N YGTA+ L+ + P +S+ G V L C G+ + + W +N
Sbjct: 294 EVSNRYGTAKVIGRLYVKQPLKAT--ISPRKVKSSVGSQVSLSC-SVTGTEDQELSWYRN 350
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G+ L + R+ ++ NL++ ++D G YQC R + + + + P +I
Sbjct: 351 GEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKII 410
Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGS----L 257
+ + V V+ C V G PLP + W GG+ + ++ + +G+ L
Sbjct: 411 SAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQM-ITSEGNVVSYL 469
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ + + D G Y C A NS G V + V P SI N + +G C
Sbjct: 470 NISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVI 528
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P ++ W N + P H F+ L ++D K C+ +
Sbjct: 529 GYPYYSIKWYKNSN---LLP-----FNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQ 580
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGE 436
S + VT + PP I + I PC + PI I W +G
Sbjct: 581 PQLS-TSQSVHVTV---KVPPFIQPFEFPR-FSIGQRVFIPCVVVSGDLPITITWQKDGR 635
Query: 437 ALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ + + N +L + +L +G YTC+A + L+V P
Sbjct: 636 PIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 689
Score = 57.6 bits (133), Expect = 3e-07
Identities = 83/349 (23%), Positives = 130/349 (37%), Gaps = 31/349 (8%)
Query: 198 IHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDDG 255
+H Y + ++VV + + C G P + W + G + ++ V +G
Sbjct: 20 LHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNG 79
Query: 256 SLRL------DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--- 306
+L++ L + Y C AEN G + + ++ P +V VE
Sbjct: 80 TLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHI----KAVLREPYTVRVEDQKT 135
Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
GNVA F C E + T+ SR +T L I D
Sbjct: 136 MRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGA------LYIKDVQNE 189
Query: 365 DSRNTIVC-SAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D C + Y G + + SD P I +G ++ PC A+
Sbjct: 190 DGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKAL 249
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
PEP W + L + R T G L+++++ SDSG+Y C S+R+G G L
Sbjct: 250 GHPEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSNRYGTAKVIGRL 308
Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKI 530
V P+ I V S G ++ +VT T LSW +N +I
Sbjct: 309 YVKQPLKATI---SPRKVKSSVGSQVS-LSCSVTGTEDQELSWYRNGEI 353
Score = 56.4 bits (130), Expect = 6e-07
Identities = 59/241 (24%), Positives = 104/241 (43%), Gaps = 33/241 (13%)
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
AV AG +TV P I+T T P V PC A+ P P + W
Sbjct: 1263 AVTSAGRGNSSEIITVEPLAKAPARILTFS-GTVTTPWMKDIVLPCKAVGDPSPAVKWMK 1321
Query: 434 EGE---ALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
+ +L+ + RR++ ++G+ +++ + DSG Y+C+A++ G S ++++
Sbjct: 1322 DSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWG----SDEIILN---- 1373
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
V P P ++ T +S+TLSW + G SSI GY ++ +S +
Sbjct: 1374 --------LQVQVPPDQPRLTVS-KTTSSSITLSWLPGDN-GGSSIRGYILQ-YSED--- 1419
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
NS W + Y +++L G Y F + +N G S + ++ T+G
Sbjct: 1420 ------NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGK 1473
Query: 610 D 610
+
Sbjct: 1474 E 1474
Score = 50.0 bits (114), Expect = 5e-05
Identities = 47/165 (28%), Positives = 73/165 (44%), Gaps = 19/165 (11%)
Query: 125 VVLECLPPRGSPEPNVYWKK--NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
+VL C G P P V W K NG L D R + G+ +I+ + D+G Y CIA
Sbjct: 1303 IVLPCKAV-GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1361
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQ-TGSSVTFQCRV---GGDPLPDVLWRRS 238
N G+ E I L++ + P P V++ T SS+T GG + + + S
Sbjct: 1362 NNNWGSDE-IILNLQVQVPP---DQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1417
Query: 239 AGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
G+ P+ + S RL+N+ +++ A+N VG
Sbjct: 1418 EDNSEQWGSFPISP----SERSYRLENLKCGTWYKFTLTAQNGVG 1458
Score = 44.4 bits (100), Expect = 0.003
Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 8/77 (10%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGLFFLRATHGRV 76
VT + L C+A G PSPA++W K LV D RSI + G F +R
Sbjct: 1295 VTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIF-SNGSFIIRTVKA-- 1351
Query: 77 HSDAGVYWCEATNSYGT 93
D+G Y C A N++G+
Sbjct: 1352 -EDSGYYSCIANNNWGS 1367
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
+ C+ GDP P V W + + G + GR + +GS + V D G YSC A
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1362
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G+ L V PP
Sbjct: 1363 NNWGSDEIILNLQVQVPP 1380
>AF023449-1|AAC17966.1| 1896|Homo sapiens Down syndrome cell adhesion
molecule protein.
Length = 1896
Score = 176 bits (428), Expect = 5e-43
Identities = 210/827 (25%), Positives = 334/827 (40%), Gaps = 71/827 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I ++T + ++CR G P +I+WYK L+ + + G L
Sbjct: 490 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSD 549
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
V D G Y C + S++ +HV V F E + + G V + C+
Sbjct: 550 VQKEV--DEGEYTCNVLVQPQLSTSQS--VHVTVKVPPFIQPFEFPRFSIGQRVFIPCVV 605
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G + W+K+G+ + + +D +L I + G Y CIARN A E
Sbjct: 606 VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 665
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN---MPL- 246
+ L + + P + P D G +V C G P+P ++W+ S G G P+
Sbjct: 666 HQ-SQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIA 724
Query: 247 --GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVN 303
GR++VL +GSL + +V+ D G Y C+ N VGA VS S YLTV P I PN+
Sbjct: 725 LNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTL 784
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTD 362
G +CTA G + W E II P M+R V + V + L I T
Sbjct: 785 ATQGQKKEMSCTAHGEKPIIVRWEKEDR--IINPEMARYLVSTKEVGEEVISTLQILPTV 842
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
+ DS C A+N G +LTV D PP I +T+ ++ F +
Sbjct: 843 REDS-GFFSCHAINSYGEDRGIIQLTVQEPPD-PPEIEIKDVKARTITLRWTMGFDGNSP 900
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
T I ++V+ N T++ D+ S + + A +R GK S
Sbjct: 901 ITGYDIECKNKSDSWDSAQRTKDVSPQLNSATII--DIHPSSTYSIRMYAKNRIGKSEPS 958
Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSSILGY 538
L + AD ++ GPP + ++ S+ ++W K + + I GY
Sbjct: 959 NELTI------------TADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGY 1006
Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
Q+ RE +G N N + + Y + +L Y +V+ N G +GP
Sbjct: 1007 QIGY--REYSTGGNFQFNI---ISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG-TGP 1060
Query: 599 SPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF 658
S T +D S + E ++A ++I + W L+
Sbjct: 1061 SSQEIITTTLEDVPS--------------------YPPENVQAIATSPESISISWSTLSK 1100
Query: 659 YYLEGLFIYFRPLDNITI-EYEMKTILHSNDVS-GFEITSLRKYTKYEFFLIPFYKKFEG 716
L G+ FR + + + E+ I + E+ L KYT Y ++ F + +G
Sbjct: 1101 EALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDG 1160
Query: 717 KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
S +T +DVP GPP ++ + + V + W PP L+L NGII Y V +
Sbjct: 1161 VRSEQIFTRTKEDVP-GPPAGVKAAAASASMVFVSWLPP-LKL-NGIIRKYTVFCS---- 1213
Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
++++ + S + NL+ YSV + A T G G S+
Sbjct: 1214 HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSE 1260
Score = 142 bits (344), Expect = 7e-33
Identities = 197/841 (23%), Positives = 329/841 (39%), Gaps = 92/841 (10%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHR---SILPAGGLF 67
P II + V+ +P +L C G+P P I W ++ +HR I G +
Sbjct: 393 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 452
Query: 68 -FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125
+L + +V D GVY C A NS G + A ++V R + P +A G
Sbjct: 453 SYLNISSSQVR-DGGVYRCTANNSAGVVLYQ-ARINV---RGPASIRPMKNITAIAGRDT 507
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQC--IA 182
+ C G P ++ W KN L F+ ++ + G L + D ++ D G Y C +
Sbjct: 508 YIHCRVI-GYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGEYTCNVLV 565
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGG 241
+ T +S T+K+ P I E G V C V LP + W++
Sbjct: 566 QPQLSTSQSVHVTVKV---PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRP 622
Query: 242 GNMPLG-RVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
LG + +D SLR+ N+ L G Y+C A N AV L V PP + P
Sbjct: 623 IPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 682
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ G C+A G P PT+ W + P + L I
Sbjct: 683 RDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGV--PQFQPIALNGRIQVLSNGSLLIK 740
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ DS +C N G+ + LTV + P +IT+ P+
Sbjct: 741 HVVEEDS-GYYLCKVSNDVGADVSKSMYLTV-----KIPAMITSYPNTTLATQGQKKEMS 794
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTND--------GTLVLKDLDKSDSGTYTCVAS 470
CTA I+ W E + R + + TL + + DSG ++C A
Sbjct: 795 CTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAI 854
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+ +G+ L V P P PP I +V ++TL W+
Sbjct: 855 NSYGEDRGIIQLTVQEP----------------PDPPEIEI-KDVKARTITLRWTMGFD- 896
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G+S I GY +E ++ S ++ R ++ +++ + + P TY + +
Sbjct: 897 GNSPITGYDIECKNKSD-SWDSAQRTKD----VSPQLNSA--TIIDIHPSSTYSIRMYAK 949
Query: 591 NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650
N G S P S+ +T+ D + D + + PI S++I+
Sbjct: 950 NRIGKSEP---SNELTITADEAA------------------PDGPPQEVHLEPISSQSIR 988
Query: 651 LMWEI----LNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705
+ W+ L + G I +R ++ + ++ S D + + +L K+T+Y
Sbjct: 989 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 1048
Query: 706 FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
+ + G S + TL+DVP PP N++ + ++ + WS + NGI+
Sbjct: 1049 VVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQ 1108
Query: 766 GYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
G+ V+ W ++ + N T Q SL + L +YS+Q+ A T G G S+++
Sbjct: 1109 GFRVIY-WANLMDGELGEIKNITTTQ-PSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQI 1166
Query: 826 Y 826
+
Sbjct: 1167 F 1167
Score = 124 bits (299), Expect = 2e-27
Identities = 126/501 (25%), Positives = 208/501 (41%), Gaps = 47/501 (9%)
Query: 13 YIIEQPLDVTVARHQPATL-NCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGLF-- 67
Y + L V TL C A G P +RWY + D R + P G L
Sbjct: 11 YFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIF 70
Query: 68 -FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
F ++ + D Y+C A N G RS++ + AVLRE + + E +++ +G+ V
Sbjct: 71 PFPPSSFSTLIHD-NTYYCTAENPSGKIRSQDVHIK-AVLREPYTVRVEDQKTMRGNVAV 128
Query: 127 LECLPPRGSPE--PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIAR 183
+C+ P V W+K+ +L+ SR + G L I+D + D Y+CI R
Sbjct: 129 FKCIIPSSVEAYITVVSWEKDTVSLV--SGSRFLITSTGALYIKDVQNEDGLYNYRCITR 186
Query: 184 N--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+ TR+S A L + + P ++ G + A G V C+ G P PD W +
Sbjct: 187 HRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLK 246
Query: 238 SAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
NMPL GR + G L ++N+ +D G Y CE N G G L V P
Sbjct: 247 D----NMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLK 301
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+SP V G+ +C+ TG + + W G I+ PG + T + +
Sbjct: 302 ATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGE--ILNPGKN---VRITGI-NHEN 355
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
++ + + + +V+ L +D P II+ P + +
Sbjct: 356 LIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVL-----EDGTPKIISAFSEKVVSPAEPV 410
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQ--NHR--RNVTNDGTLV----LKDLDKSDSGTYT 466
++ C TP P I W + + +++ +HR + +T++G +V + D G Y
Sbjct: 411 SLM-CNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 469
Query: 467 CVASSRHGKYVWSGALLVDSP 487
C A++ G ++ + V P
Sbjct: 470 CTANNSAGVVLYQARINVRGP 490
Score = 109 bits (261), Expect = 8e-23
Identities = 112/474 (23%), Positives = 184/474 (38%), Gaps = 37/474 (7%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
Q L C+A G P P RW K + L +S + + + +R SD+G Y C
Sbjct: 226 QRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRP------SDSGSYVC 279
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
E +N YGTA+ L+ + P +S+ G V L C G+ + + W +N
Sbjct: 280 EVSNRYGTAKVIGRLYVKQPLKAT--ISPRKVKSSVGSQVSLSC-SVTGTEDQELSWYRN 336
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G+ L + R+ ++ NL++ ++D G YQC R + + + + P +I
Sbjct: 337 GEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKII 396
Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGS----L 257
+ + V V+ C V G PLP + W GG+ + ++ + +G+ L
Sbjct: 397 SAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQM-ITSEGNVVSYL 455
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ + + D G Y C A NS G V + V P SI N + +G C
Sbjct: 456 NISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVI 514
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P ++ W N + P H F+ L ++D K C+ +
Sbjct: 515 GYPYYSIKWYKNSN---LLP-----FNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQ 566
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGE 436
S + VT + PP I + I PC + PI I W +G
Sbjct: 567 PQLS-TSQSVHVTV---KVPPFIQPFEFPR-FSIGQRVFIPCVVVSGDLPITITWQKDGR 621
Query: 437 ALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ + + N +L + +L +G YTC+A + L+V P
Sbjct: 622 PIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 675
Score = 57.6 bits (133), Expect = 3e-07
Identities = 83/349 (23%), Positives = 130/349 (37%), Gaps = 31/349 (8%)
Query: 198 IHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDDG 255
+H Y + ++VV + + C G P + W + G + ++ V +G
Sbjct: 6 LHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNG 65
Query: 256 SLRL------DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--- 306
+L++ L + Y C AEN G + + ++ P +V VE
Sbjct: 66 TLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHI----KAVLREPYTVRVEDQKT 121
Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
GNVA F C E + T+ SR +T L I D
Sbjct: 122 MRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGA------LYIKDVQNE 175
Query: 365 DSRNTIVC-SAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D C + Y G + + SD P I +G ++ PC A+
Sbjct: 176 DGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCKAL 235
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
PEP W + L + R T G L+++++ SDSG+Y C S+R+G G L
Sbjct: 236 GHPEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSNRYGTAKVIGRL 294
Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKI 530
V P+ I V S G ++ +VT T LSW +N +I
Sbjct: 295 YVKQPLKATI---SPRKVKSSVGSQVS-LSCSVTGTEDQELSWYRNGEI 339
Score = 56.4 bits (130), Expect = 6e-07
Identities = 59/241 (24%), Positives = 104/241 (43%), Gaps = 33/241 (13%)
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
AV AG +TV P I+T T P V PC A+ P P + W
Sbjct: 1249 AVTSAGRGNSSEIITVEPLAKAPARILTFS-GTVTTPWMKDIVLPCKAVGDPSPAVKWMK 1307
Query: 434 EGE---ALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
+ +L+ + RR++ ++G+ +++ + DSG Y+C+A++ G S ++++
Sbjct: 1308 DSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWG----SDEIILN---- 1359
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
V P P ++ T +S+TLSW + G SSI GY ++ +S +
Sbjct: 1360 --------LQVQVPPDQPRLTVS-KTTSSSITLSWLPGDN-GGSSIRGYILQ-YSED--- 1405
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
NS W + Y +++L G Y F + +N G S + ++ T+G
Sbjct: 1406 ------NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGK 1459
Query: 610 D 610
+
Sbjct: 1460 E 1460
Score = 50.0 bits (114), Expect = 5e-05
Identities = 47/165 (28%), Positives = 73/165 (44%), Gaps = 19/165 (11%)
Query: 125 VVLECLPPRGSPEPNVYWKK--NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
+VL C G P P V W K NG L D R + G+ +I+ + D+G Y CIA
Sbjct: 1289 IVLPCKAV-GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1347
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQ-TGSSVTFQCRV---GGDPLPDVLWRRS 238
N G+ E I L++ + P P V++ T SS+T GG + + + S
Sbjct: 1348 NNNWGSDE-IILNLQVQVPP---DQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1403
Query: 239 AGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
G+ P+ + S RL+N+ +++ A+N VG
Sbjct: 1404 EDNSEQWGSFPISP----SERSYRLENLKCGTWYKFTLTAQNGVG 1444
Score = 44.4 bits (100), Expect = 0.003
Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 8/77 (10%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGLFFLRATHGRV 76
VT + L C+A G PSPA++W K LV D RSI + G F +R
Sbjct: 1281 VTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIF-SNGSFIIRTVKA-- 1337
Query: 77 HSDAGVYWCEATNSYGT 93
D+G Y C A N++G+
Sbjct: 1338 -EDSGYYSCIANNNWGS 1353
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
+ C+ GDP P V W + + G + GR + +GS + V D G YSC A
Sbjct: 1289 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1348
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G+ L V PP
Sbjct: 1349 NNWGSDEIILNLQVQVPP 1366
>AB209136-1|BAD92373.1| 2023|Homo sapiens Down syndrome cell adhesion
molecule isoform CHD2-42 precursor variant protein.
Length = 2023
Score = 176 bits (428), Expect = 5e-43
Identities = 210/827 (25%), Positives = 334/827 (40%), Gaps = 71/827 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I ++T + ++CR G P +I+WYK L+ + + G L
Sbjct: 515 PASIRPMKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSD 574
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
V D G Y C + S++ +HV V F E + + G V + C+
Sbjct: 575 VQKEV--DEGEYTCNVLVQPQLSTSQS--VHVTVKVPPFIQPFEFPRFSIGQRVFIPCVV 630
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G + W+K+G+ + + +D +L I + G Y CIARN A E
Sbjct: 631 VSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVE 690
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN---MPL- 246
+ L + + P + P D G +V C G P+P ++W+ S G G P+
Sbjct: 691 HQ-SQLIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIA 749
Query: 247 --GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVN 303
GR++VL +GSL + +V+ D G Y C+ N VGA VS S YLTV P I PN+
Sbjct: 750 LNGRIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTL 809
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV-TVLTINDTD 362
G +CTA G + W E II P M+R V + V + L I T
Sbjct: 810 ATQGQKKEMSCTAHGEKPIIVRWEKEDR--IINPEMARYLVSTKEVGEEVISTLQILPTV 867
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
+ DS C A+N G +LTV D PP I +T+ ++ F +
Sbjct: 868 REDS-GFFSCHAINSYGEDRGIIQLTVQEPPD-PPEIEIKDVKARTITLRWTMGFDGNSP 925
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
T I ++V+ N T++ D+ S + + A +R GK S
Sbjct: 926 ITGYDIECKNKSDSWDSAQRTKDVSPQLNSATII--DIHPSSTYSIRMYAKNRIGKSEPS 983
Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSSILGY 538
L + AD ++ GPP + ++ S+ ++W K + + I GY
Sbjct: 984 NELTI------------TADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGY 1031
Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
Q+ RE +G N N + + Y + +L Y +V+ N G +GP
Sbjct: 1032 QIGY--REYSTGGNFQFNI---ISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAG-TGP 1085
Query: 599 SPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNF 658
S T +D S + E ++A ++I + W L+
Sbjct: 1086 SSQEIITTTLEDVPS--------------------YPPENVQAIATSPESISISWSTLSK 1125
Query: 659 YYLEGLFIYFRPLDNITI-EYEMKTILHSNDVS-GFEITSLRKYTKYEFFLIPFYKKFEG 716
L G+ FR + + + E+ I + E+ L KYT Y ++ F + +G
Sbjct: 1126 EALNGILQGFRVIYWANLMDGELGEIKNITTTQPSLELDGLEKYTNYSIQVLAFTRAGDG 1185
Query: 717 KPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
S +T +DVP GPP ++ + + V + W PP L+L NGII Y V +
Sbjct: 1186 VRSEQIFTRTKEDVP-GPPAGVKAAAASASMVFVSWLPP-LKL-NGIIRKYTVFCS---- 1238
Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
++++ + S + NL+ YSV + A T G G S+
Sbjct: 1239 HPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNSSE 1285
Score = 142 bits (344), Expect = 7e-33
Identities = 197/841 (23%), Positives = 329/841 (39%), Gaps = 92/841 (10%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHR---SILPAGGLF 67
P II + V+ +P +L C G+P P I W ++ +HR I G +
Sbjct: 418 PKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVV 477
Query: 68 -FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTV 125
+L + +V D GVY C A NS G + A ++V R + P +A G
Sbjct: 478 SYLNISSSQVR-DGGVYRCTANNSAGVVLYQ-ARINV---RGPASIRPMKNITAIAGRDT 532
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQC--IA 182
+ C G P ++ W KN L F+ ++ + G L + D ++ D G Y C +
Sbjct: 533 YIHCRVI-GYPYYSIKWYKNSNLLPFN-HRQVAFENNGTLKLSDVQKEVDEGEYTCNVLV 590
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSAGG 241
+ T +S T+K+ P I E G V C V LP + W++
Sbjct: 591 QPQLSTSQSVHVTVKV---PPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRP 647
Query: 242 GNMPLG-RVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
LG + +D SLR+ N+ L G Y+C A N AV L V PP + P
Sbjct: 648 IPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVPPKFVVQP 707
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ G C+A G P PT+ W + P + L I
Sbjct: 708 RDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGV--PQFQPIALNGRIQVLSNGSLLIK 765
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ DS +C N G+ + LTV + P +IT+ P+
Sbjct: 766 HVVEEDS-GYYLCKVSNDVGADVSKSMYLTV-----KIPAMITSYPNTTLATQGQKKEMS 819
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTND--------GTLVLKDLDKSDSGTYTCVAS 470
CTA I+ W E + R + + TL + + DSG ++C A
Sbjct: 820 CTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAI 879
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+ +G+ L V P P PP I +V ++TL W+
Sbjct: 880 NSYGEDRGIIQLTVQEP----------------PDPPEIEI-KDVKARTITLRWTMGFD- 921
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G+S I GY +E ++ S ++ R ++ +++ + + P TY + +
Sbjct: 922 GNSPITGYDIECKNKSD-SWDSAQRTKD----VSPQLNSA--TIIDIHPSSTYSIRMYAK 974
Query: 591 NSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIK 650
N G S P S+ +T+ D + D + + PI S++I+
Sbjct: 975 NRIGKSEP---SNELTITADEAA------------------PDGPPQEVHLEPISSQSIR 1013
Query: 651 LMWEI----LNFYYLEGLFIYFRPLD-NITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705
+ W+ L + G I +R ++ + ++ S D + + +L K+T+Y
Sbjct: 1014 VTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDSEVYTLDNLNKFTQYGL 1073
Query: 706 FLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
+ + G S + TL+DVP PP N++ + ++ + WS + NGI+
Sbjct: 1074 VVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQ 1133
Query: 766 GYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
G+ V+ W ++ + N T Q SL + L +YS+Q+ A T G G S+++
Sbjct: 1134 GFRVIY-WANLMDGELGEIKNITTTQ-PSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQI 1191
Query: 826 Y 826
+
Sbjct: 1192 F 1192
Score = 125 bits (302), Expect = 8e-28
Identities = 127/501 (25%), Positives = 208/501 (41%), Gaps = 47/501 (9%)
Query: 13 YIIEQPLDVTVARHQPATL-NCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGLF-- 67
Y + L V TL C A G P +RWY + D R + P G L
Sbjct: 36 YFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTLQIF 95
Query: 68 -FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
F ++ + D Y+C A N G RS++ + AVLRE + + E +++ +G+ V
Sbjct: 96 PFPPSSFSTLIHD-NTYYCTAENPSGKIRSQDVHIK-AVLREPYTVRVEDQKTMRGNVAV 153
Query: 127 LECLPPRGSPE--PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIAR 183
+C+ P V W+K+ +L+ SR + G L I+D + D Y+CI R
Sbjct: 154 FKCIIPSSVEAYITVVSWEKDTVSLV--SGSRFLITSTGALYIKDVQNEDGLYNYRCITR 211
Query: 184 N--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+ TR+S A L + + P ++ G E A G V C+ G P PD W +
Sbjct: 212 HRYTGETRQSNSARLFVSDPANSAPSILDGFEHRKAMAGQRVELPCKALGHPEPDYRWLK 271
Query: 238 SAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
NMPL GR + G L ++N+ +D G Y CE N G G L V P
Sbjct: 272 D----NMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVKQPLK 326
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+SP V G+ +C+ TG + + W G I+ PG + T + +
Sbjct: 327 ATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGE--ILNPGKN---VRITGI-NHEN 380
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
++ + + + +V+ L +D P II+ P + +
Sbjct: 381 LIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVL-----EDGTPKIISAFSEKVVSPAEPV 435
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQ--NHR--RNVTNDGTLV----LKDLDKSDSGTYT 466
++ C TP P I W + + +++ +HR + +T++G +V + D G Y
Sbjct: 436 SLM-CNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYR 494
Query: 467 CVASSRHGKYVWSGALLVDSP 487
C A++ G ++ + V P
Sbjct: 495 CTANNSAGVVLYQARINVRGP 515
Score = 109 bits (261), Expect = 8e-23
Identities = 112/474 (23%), Positives = 184/474 (38%), Gaps = 37/474 (7%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
Q L C+A G P P RW K + L +S + + + +R SD+G Y C
Sbjct: 251 QRVELPCKALGHPEPDYRWLKDNMPLELSGRFQKTVTGLLIENIRP------SDSGSYVC 304
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
E +N YGTA+ L+ + P +S+ G V L C G+ + + W +N
Sbjct: 305 EVSNRYGTAKVIGRLYVKQPLKAT--ISPRKVKSSVGSQVSLSC-SVTGTEDQELSWYRN 361
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G+ L + R+ ++ NL++ ++D G YQC R + + + + P +I
Sbjct: 362 GEILNPGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKII 421
Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGS----L 257
+ + V V+ C V G PLP + W GG+ + ++ + +G+ L
Sbjct: 422 SAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQM-ITSEGNVVSYL 480
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ + + D G Y C A NS G V + V P SI N + +G C
Sbjct: 481 NISSSQVRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKN-ITAIAGRDTYIHCRVI 539
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P ++ W N + P H F+ L ++D K C+ +
Sbjct: 540 GYPYYSIKWYKNSN---LLP-----FNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQ 591
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGE 436
S + VT + PP I + I PC + PI I W +G
Sbjct: 592 PQLS-TSQSVHVTV---KVPPFIQPFEFPR-FSIGQRVFIPCVVVSGDLPITITWQKDGR 646
Query: 437 ALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ + + N +L + +L +G YTC+A + L+V P
Sbjct: 647 PIPGSLGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 700
Score = 57.6 bits (133), Expect = 3e-07
Identities = 83/349 (23%), Positives = 130/349 (37%), Gaps = 31/349 (8%)
Query: 198 IHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDDG 255
+H Y + ++VV + + C G P + W + G + ++ V +G
Sbjct: 31 LHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNG 90
Query: 256 SLRL------DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES--- 306
+L++ L + Y C AEN G + + ++ P +V VE
Sbjct: 91 TLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHI----KAVLREPYTVRVEDQKT 146
Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
GNVA F C E + T+ SR +T L I D
Sbjct: 147 MRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGA------LYIKDVQNE 200
Query: 365 DSRNTIVC-SAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
D C + Y G + + SD P I +G ++ PC A+
Sbjct: 201 DGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFEHRKAMAGQRVELPCKAL 260
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
PEP W + L + R T G L+++++ SDSG+Y C S+R+G G L
Sbjct: 261 GHPEPDYRWLKDNMPLELSGRFQKTVTG-LLIENIRPSDSGSYVCEVSNRYGTAKVIGRL 319
Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKI 530
V P+ I V S G ++ +VT T LSW +N +I
Sbjct: 320 YVKQPLKATI---SPRKVKSSVGSQVS-LSCSVTGTEDQELSWYRNGEI 364
Score = 56.4 bits (130), Expect = 6e-07
Identities = 59/241 (24%), Positives = 104/241 (43%), Gaps = 33/241 (13%)
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
AV AG +TV P I+T T P V PC A+ P P + W
Sbjct: 1274 AVTSAGRGNSSEIITVEPLAKAPARILTFS-GTVTTPWMKDIVLPCKAVGDPSPAVKWMK 1332
Query: 434 EGE---ALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
+ +L+ + RR++ ++G+ +++ + DSG Y+C+A++ G S ++++
Sbjct: 1333 DSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNNWG----SDEIILN---- 1384
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
V P P ++ T +S+TLSW + G SSI GY ++ +S +
Sbjct: 1385 --------LQVQVPPDQPRLTVS-KTTSSSITLSWLPGDN-GGSSIRGYILQ-YSED--- 1430
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
NS W + Y +++L G Y F + +N G S + ++ T+G
Sbjct: 1431 ------NSEQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGK 1484
Query: 610 D 610
+
Sbjct: 1485 E 1485
Score = 50.0 bits (114), Expect = 5e-05
Identities = 47/165 (28%), Positives = 73/165 (44%), Gaps = 19/165 (11%)
Query: 125 VVLECLPPRGSPEPNVYWKK--NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
+VL C G P P V W K NG L D R + G+ +I+ + D+G Y CIA
Sbjct: 1314 IVLPCKAV-GDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIA 1372
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQ-TGSSVTFQCRV---GGDPLPDVLWRRS 238
N G+ E I L++ + P P V++ T SS+T GG + + + S
Sbjct: 1373 NNNWGSDE-IILNLQVQVPP---DQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS 1428
Query: 239 AGG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
G+ P+ + S RL+N+ +++ A+N VG
Sbjct: 1429 EDNSEQWGSFPISP----SERSYRLENLKCGTWYKFTLTAQNGVG 1469
Score = 44.4 bits (100), Expect = 0.003
Identities = 28/77 (36%), Positives = 38/77 (49%), Gaps = 8/77 (10%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGG----VLVVSDTHRSILPAGGLFFLRATHGRV 76
VT + L C+A G PSPA++W K LV D RSI + G F +R
Sbjct: 1306 VTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIF-SNGSFIIRTVKA-- 1362
Query: 77 HSDAGVYWCEATNSYGT 93
D+G Y C A N++G+
Sbjct: 1363 -EDSGYYSCIANNNWGS 1378
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
+ C+ GDP P V W + + G + GR + +GS + V D G YSC A
Sbjct: 1314 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIAN 1373
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G+ L V PP
Sbjct: 1374 NNWGSDEIILNLQVQVPP 1391
>AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase
protein.
Length = 1463
Score = 174 bits (424), Expect = 1e-42
Identities = 112/376 (29%), Positives = 179/376 (47%), Gaps = 21/376 (5%)
Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
EP+ + G+TV C G+P+P + W N +L + D+R+++ D G L+I++ R+
Sbjct: 239 EPQDVEVPSGNTVYFTCRA-EGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIRNTRE 297
Query: 173 TDAGRYQCIARNAAGTRESAIATLK---IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
+D G YQC+ARN+AG ++ A L+ + KP + P+D G+S T +C G P
Sbjct: 298 SDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTSTTLECMATGHP 357
Query: 230 LPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
P + W R G + L G V L L N+ D G ++C A NS G V A+ +
Sbjct: 358 HPLITWTRDNG---LELDGSRHVATSSGLYLQNITQRDHGRFTCHANNSHGTVQAAANII 414
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
V PP ++P V + + C A G P P + W+ G + + + H T
Sbjct: 415 VQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPV------EGQH-TV 467
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
+ G L I+ ++D + C AV+ G V +LTV + + T P + +
Sbjct: 468 LSSG--TLRIDRAAQHD-QGQYECQAVSSLGVKKVSVQLTV---KPKALAVFTQLPQDTS 521
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
+ + C A P+PII W EG + ++ + +V ++GTL + D D G Y CV
Sbjct: 522 VEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFHVDDEGTLTIYDAGFPDQGRYECV 581
Query: 469 ASSRHGKYVWSGALLV 484
A + G V + L V
Sbjct: 582 ARNSFGLAVTNMFLTV 597
Score = 168 bits (408), Expect = 1e-40
Identities = 123/394 (31%), Positives = 185/394 (46%), Gaps = 30/394 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFF 68
++P I +P DV V CRA G+P P I W + L + D R + G
Sbjct: 232 QSPRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLM 291
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL--REEFRLEPESKQSAQGDTVV 126
+R T SD GVY C A NS G A++++A L + L + F ++P+ + G +
Sbjct: 292 IRNTR---ESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTSTT 348
Query: 127 LECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
LEC+ G P P + W + NG L D H+ L +Q+ Q D GR+ C A N+
Sbjct: 349 LECM-ATGHPHPLITWTRDNGLEL----DGSRHVATSSGLYLQNITQRDHGRFTCHANNS 403
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
GT ++A A + + P P+D V +V + C G+P P ++W ++ GG +P
Sbjct: 404 HGTVQAA-ANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKT--GGQLP 460
Query: 246 L-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL---SPNS 301
+ G+ VL G+LR+D D+G+Y C+A +S+G S LTV P ++ + P
Sbjct: 461 VEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTV-KPKALAVFTQLPQD 519
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+VE G +C A G P+P + W+ EG + K+H D LTI D
Sbjct: 520 TSVEVGKNINISCHAQGEPQPIITWNKEGVQI-----TESGKFHV----DDEGTLTIYDA 570
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
D + C A N G + LTVT+ R
Sbjct: 571 GFPD-QGRYECVARNSFGLAVTNMFLTVTAIQGR 603
Score = 106 bits (255), Expect = 4e-22
Identities = 78/278 (28%), Positives = 117/278 (42%), Gaps = 21/278 (7%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLD 260
P + P+DV +G++V F CR G+P P+++W + ++ R+ V DDG+L +
Sbjct: 234 PRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTRLNVFDDGTLMIR 293
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVNVESGNVARFTCTA 316
N +D+G Y C A NS G + Y PS + P V G C A
Sbjct: 294 NTRESDQGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQPQDTEVLIGTSTTLECMA 353
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
TG P P + W+ + G+ D A G+ + I T ++ R T C A N
Sbjct: 354 TGHPHPLITWTRDN-------GLELDGSRHVATSSGLYLQNI--TQRDHGRFT--CHANN 402
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
G+ + V + PP T P +Q + + + C A P P+I W G
Sbjct: 403 SHGTVQAAANIIV-----QAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGG 457
Query: 437 ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
L + V + GTL + + D G Y C A S G
Sbjct: 458 QLPVEGQHTVLSSGTLRIDRAAQHDQGQYECQAVSSLG 495
Score = 80.6 bits (190), Expect = 3e-14
Identities = 55/195 (28%), Positives = 87/195 (44%), Gaps = 10/195 (5%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I P V V SGN FTC A G P+P + W + N ++ +R VFD
Sbjct: 234 PRITFEPQDVEVPSGNTVYFTCRAEGNPKPEIIW-IHNNHSLDLEDDTR-----LNVFDD 287
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
T L I +T ++D + C A N AG + + + S P + P + + I
Sbjct: 288 GT-LMIRNTRESD-QGVYQCMARNSAGEAKTQSAMLRYSSLPAKPSFVIQ-PQDTEVLIG 344
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
+ C A P P+I W + + R T+ G L L+++ + D G +TC A++
Sbjct: 345 TSTTLECMATGHPHPLITWTRDNGLELDGSRHVATSSG-LYLQNITQRDHGRFTCHANNS 403
Query: 473 HGKYVWSGALLVDSP 487
HG + ++V +P
Sbjct: 404 HGTVQAAANIIVQAP 418
>X76132-1|CAA53735.1| 1447|Homo sapiens tumour suppressor protein.
Length = 1447
Score = 170 bits (414), Expect = 2e-41
Identities = 186/727 (25%), Positives = 290/727 (39%), Gaps = 78/727 (10%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F EP + +G V+L+C P + WKK+G L D R + G+L+IQ+
Sbjct: 42 FLSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQN 101
Query: 170 A-----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
+ D G YQC A +G+ S A + + ++ E V A G +V +C
Sbjct: 102 ILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKC 161
Query: 224 RVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
V G+P+P + W+++ G RV VL G+L++ + D G Y C A N +
Sbjct: 162 EVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSR 221
Query: 282 SAS-GYLTVYDPPSINLS------PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
+ + + + P ++ P++V G A C +G P P+ W + G I
Sbjct: 222 TGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTW-LRGEEVI 280
Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
+ KY ++ G +L N TD + T V + N S+ +LTV
Sbjct: 281 ---QLRSKKY---SLLGGSNLLISNVTDDDSGMYTCVVTYKNENISA--SAELTVLV--- 329
Query: 395 RPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV 453
PP N PSN +SM + F CT P P + W G+ +I + + L
Sbjct: 330 --PPWFLNHPSN-LYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLR 386
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ + KSD G Y CVA + G S L+V P P+ S LP P +
Sbjct: 387 ILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPS--------SSVLPSAPRDVVPV 438
Query: 514 NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
V+ V LSW + +I + V FSRE G+N R + +
Sbjct: 439 LVSSRFVRLSWRPPAE-AKGNIQTFTV-FFSRE---GDNRER-----ALNTTQPGSLQLT 488
Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTD 633
V +L P Y F V N GP S + V G
Sbjct: 489 VGNLKPEAMYTFRVVAYNEW---GPGESSQPIKVATQPELQVPGP--------------- 530
Query: 634 HIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFE 693
VE ++A +I + WE Y G +R + + I D ++
Sbjct: 531 --VENLQAVSTSPTSILITWE--PPAYANGPVQGYRLFCTEVSTGKEQNI--EVDGLSYK 584
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+ L+K+T+Y + + + G ++ TL DVP PP N+ + ++N+ ++ + W
Sbjct: 585 LEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWL 644
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
PP QNG ITGY + + N + + T L G YS Q++A
Sbjct: 645 PPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWY-----LFTGLEKGSQYSFQVSAM 699
Query: 814 TIIGLGP 820
T+ G GP
Sbjct: 700 TVNGTGP 706
Score = 153 bits (372), Expect = 3e-36
Identities = 130/417 (31%), Positives = 183/417 (43%), Gaps = 35/417 (8%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPS-PAIRWYKGGVLVV--SDTHRSILPAGGLFFLRA 71
+ +P D R L+C A P I+W K G+ + D + L G L
Sbjct: 43 LSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNI 102
Query: 72 THGRVHS-DAGVYWCEAT-NSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLE 128
H R H D G+Y CEA+ G+ SR A + VA LR F + ES + GDTV+L+
Sbjct: 103 LHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLR--FLSQTESVTAFMGDTVLLK 160
Query: 129 CLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P P ++W+KN Q L GDSR+ ++ G L I + D G Y+C ARN A
Sbjct: 161 C-EVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPAS 219
Query: 188 TRESAIATLKI------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
+R A ++I H + Y + P +VVA G +C V G P P W R
Sbjct: 220 SRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEV 279
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
+ + +L +L + NV D G Y+C +SAS LTV PP P++
Sbjct: 280 IQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSN 339
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ F CT +G+P PT+ W G+ ++ P D + G + L I
Sbjct: 340 LYAYESMDIEFECTVSGKPVPTVNWMKNGD--VVIPS---DYFQIV----GGSNLRILGV 390
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
K+D C A N AG++ +L V P P I PS+ LP V P
Sbjct: 391 VKSD-EGFYQCVAENEAGNAQTSAQLIV------PKPAI---PSSSVLPSAPRDVVP 437
Score = 74.5 bits (175), Expect = 2e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 14/211 (6%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRA 71
Y +++P +V + A L C G P P+ W +G V+ + S+L L
Sbjct: 241 YFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNV 300
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
T D+G+Y C T S +A L V V F P + + + + EC
Sbjct: 301 T----DDDSGMYTCVVTYKNENI-SASAELTVLV-PPWFLNHPSNLYAYESMDIEFEC-T 353
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
G P P V W KNG ++ +V G NL I ++D G YQC+A N AG ++
Sbjct: 354 VSGKPVPTVNWMKNGDVVI--PSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQT 411
Query: 192 AIATL----KIHIKPYLITGPEDVVAQTGSS 218
+ + I L + P DVV SS
Sbjct: 412 SAQLIVPKPAIPSSSVLPSAPRDVVPVLVSS 442
Score = 46.0 bits (104), Expect = 8e-04
Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 4/85 (4%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P+ + P ++ C G P P + W K G +V+ + I+ L L
Sbjct: 331 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL-- 388
Query: 72 THGRVHSDAGVYWCEATNSYGTARS 96
G V SD G Y C A N G A++
Sbjct: 389 --GVVKSDEGFYQCVAENEAGNAQT 411
>M32292-1|AAA35751.1| 750|Homo sapiens protein ( Human colorectal
tumor suppressor mRNA (DCC), 5' end. ).
Length = 750
Score = 170 bits (414), Expect = 2e-41
Identities = 186/727 (25%), Positives = 290/727 (39%), Gaps = 78/727 (10%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F EP + +G V+L+C P + WKK+G L D R + G+L+IQ+
Sbjct: 42 FLSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQN 101
Query: 170 A-----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
+ D G YQC A +G+ S A + + ++ E V A G +V +C
Sbjct: 102 ILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKC 161
Query: 224 RVGGDPLPDVLWRRSAGGGNMPLG--RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
V G+P+P + W+++ G RV VL G+L++ + D G Y C A N +
Sbjct: 162 EVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSR 221
Query: 282 SAS-GYLTVYDPPSINLS------PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
+ + + + P ++ P++V G A C +G P P+ W + G I
Sbjct: 222 TGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTW-LRGEEVI 280
Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
+ KY ++ G +L N TD + T V + N S+ +LTV
Sbjct: 281 ---QLRSKKY---SLLGGSNLLISNVTDDDSGMYTCVVTYKNENISA--SAELTVLV--- 329
Query: 395 RPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV 453
PP N PSN +SM + F CT P P + W G+ +I + + L
Sbjct: 330 --PPWFLNHPSN-LYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLR 386
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ + KSD G Y CVA + G S L+V P P+ S LP P +
Sbjct: 387 ILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPS--------SSVLPSAPRDVVPV 438
Query: 514 NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
V+ V LSW + +I + V FSRE G+N R + +
Sbjct: 439 LVSSRFVRLSWRPPAE-AKGNIQTFTV-FFSRE---GDNRER-----ALNTTQPGSLQLT 488
Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTD 633
V +L P Y F V N GP S + V G
Sbjct: 489 VGNLKPEAMYTFRVVAYNEW---GPGESSQPIKVATQPELQVPGP--------------- 530
Query: 634 HIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFE 693
VE ++A +I + WE Y G +R + + I D ++
Sbjct: 531 --VENLQAVSTSPTSILITWE--PPAYANGPVQGYRLFCTEVSTGKEQNI--EVDGLSYK 584
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+ L+K+T+Y + + + G ++ TL DVP PP N+ + ++N+ ++ + W
Sbjct: 585 LEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWL 644
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
PP QNG ITGY + + N + + T L G YS Q++A
Sbjct: 645 PPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWY-----LFTGLEKGSQYSFQVSAM 699
Query: 814 TIIGLGP 820
T+ G GP
Sbjct: 700 TVNGTGP 706
Score = 153 bits (372), Expect = 3e-36
Identities = 130/417 (31%), Positives = 183/417 (43%), Gaps = 35/417 (8%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPS-PAIRWYKGGVLVV--SDTHRSILPAGGLFFLRA 71
+ +P D R L+C A P I+W K G+ + D + L G L
Sbjct: 43 LSEPSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNI 102
Query: 72 THGRVHS-DAGVYWCEAT-NSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLE 128
H R H D G+Y CEA+ G+ SR A + VA LR F + ES + GDTV+L+
Sbjct: 103 LHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLR--FLSQTESVTAFMGDTVLLK 160
Query: 129 CLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G P P ++W+KN Q L GDSR+ ++ G L I + D G Y+C ARN A
Sbjct: 161 C-EVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPAS 219
Query: 188 TRESAIATLKI------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
+R A ++I H + Y + P +VVA G +C V G P P W R
Sbjct: 220 SRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEV 279
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
+ + +L +L + NV D G Y+C +SAS LTV PP P++
Sbjct: 280 IQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNHPSN 339
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ F CT +G+P PT+ W G+ ++ P D + G + L I
Sbjct: 340 LYAYESMDIEFECTVSGKPVPTVNWMKNGD--VVIPS---DYFQIV----GGSNLRILGV 390
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
K+D C A N AG++ +L V P P I PS+ LP V P
Sbjct: 391 VKSD-EGFYQCVAENEAGNAQTSAQLIV------PKPAI---PSSSVLPSAPRDVVP 437
Score = 74.5 bits (175), Expect = 2e-12
Identities = 60/211 (28%), Positives = 88/211 (41%), Gaps = 14/211 (6%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRA 71
Y +++P +V + A L C G P P+ W +G V+ + S+L L
Sbjct: 241 YFLQRPSNVVAIEGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNV 300
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
T D+G+Y C T S +A L V V F P + + + + EC
Sbjct: 301 T----DDDSGMYTCVVTYKNENI-SASAELTVLV-PPWFLNHPSNLYAYESMDIEFEC-T 353
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
G P P V W KNG ++ +V G NL I ++D G YQC+A N AG ++
Sbjct: 354 VSGKPVPTVNWMKNGDVVI--PSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQT 411
Query: 192 AIATL----KIHIKPYLITGPEDVVAQTGSS 218
+ + I L + P DVV SS
Sbjct: 412 SAQLIVPKPAIPSSSVLPSAPRDVVPVLVSS 442
Score = 46.0 bits (104), Expect = 8e-04
Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 4/85 (4%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P+ + P ++ C G P P + W K G +V+ + I+ L L
Sbjct: 331 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL-- 388
Query: 72 THGRVHSDAGVYWCEATNSYGTARS 96
G V SD G Y C A N G A++
Sbjct: 389 --GVVKSDEGFYQCVAENEAGNAQT 411
>X68274-1|CAA48335.1| 1040|Homo sapiens TAG-1/axonin-1 precursor
protein.
Length = 1040
Score = 169 bits (412), Expect = 4e-41
Identities = 140/492 (28%), Positives = 209/492 (42%), Gaps = 42/492 (8%)
Query: 12 PYIIEQPLDVTV---ARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67
P +QPL V + + L CRA SP RW G + + R L G L
Sbjct: 37 PVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLV 96
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ T + DAGVY C A+N GT SR A L L+E + E + ++ +G V+L
Sbjct: 97 IMNPTKAQ---DAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVML 153
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNA 185
C PP P + W N D R H V GNL I +D G Y C+A +
Sbjct: 154 PCNPPAHYPGLSYRWLLNEFPNFIPTDGR-HFVSQTTGNLYIARTNASDLGNYSCLATSH 212
Query: 186 A--GTRE--SAIATLKIHIKPYLITGPE-------DVVAQTGSSVTFQCRVGGDPLPDVL 234
T+ S A L + + + P + A G VT +C G+P+P +
Sbjct: 213 MDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIK 272
Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
WR+ G L + +L++ +V DEG Y CEAENS G + G + V P
Sbjct: 273 WRKVDGS----LSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPE 328
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+ + G+ R+ C A G+P PT+ W G P S+++ A +
Sbjct: 329 WLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGE-----PLASQNRVEVLAGDLRFS 383
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-- 412
L++ D+ C A N G+ + +L V + P P + +P
Sbjct: 384 KLSLEDS------GMYQCVAENKHGTIYASAELAVQA----LAPDFRLNPVRRLIPAARG 433
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
+ PC P+ ++ W E L+ + R VT DGTL+++++ +SD G YTC A +
Sbjct: 434 GEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENF 493
Query: 473 HGKYVWSGALLV 484
GK +G L V
Sbjct: 494 MGKANSTGILSV 505
Score = 108 bits (259), Expect = 1e-22
Identities = 87/309 (28%), Positives = 136/309 (44%), Gaps = 22/309 (7%)
Query: 27 QPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYW 84
Q TL C A G+P P I+W K G + T L + F D G Y
Sbjct: 255 QQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSF---------EDEGTYE 305
Query: 85 CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
CEA NS G + + A + E+ ++ G + C G P P V W +
Sbjct: 306 CEAENSKGRDTVQGRIIVQA--QPEWLKVISDTEADIGSNLRWGCAAA-GKPRPTVRWLR 362
Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
NG+ L +R+ ++ G+L D+G YQC+A N GT ++ + P
Sbjct: 363 NGEPLA--SQNRVEVL-AGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDF 419
Query: 205 ITGPED--VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV 262
P + A G + C+ P VLW + + RV V DG+L + N+
Sbjct: 420 RLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEI-LVNSSRVTVTPDGTLIIRNI 478
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP-- 320
+DEG+Y+C AEN +G +++G L+V D I L+P+S ++ G+ C A+ P
Sbjct: 479 SRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTM 538
Query: 321 EPTMFWSVE 329
+ T W+++
Sbjct: 539 DLTFTWTLD 547
Score = 107 bits (257), Expect = 2e-22
Identities = 133/491 (27%), Positives = 192/491 (39%), Gaps = 58/491 (11%)
Query: 59 SILPAGGLFFLRATHGRVH------SDAGVYWCEATN----SYGTARSRNATLHVAVLRE 108
+ +P G F+ T G ++ SD G Y C AT+ S + S+ A L++A E
Sbjct: 175 NFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAA--E 232
Query: 109 EFRLE--------PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV 160
+ RL P + G V LEC G+P P + W+K +L S
Sbjct: 233 DTRLFAPSIKARFPAETYALVGQQVTLECFA-FGNPVPRIKWRKVDGSL-----SPQWTT 286
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
L I D G Y+C A N+ G R++ + + +P + D A GS++
Sbjct: 287 AEPTLQIPSVSFEDEGTYECEAENSKG-RDTVQGRIIVQAQPEWLKVISDTEADIGSNLR 345
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
+ C G P P V W R+ G RV+VL G LR + L D G Y C AEN G
Sbjct: 346 WGCAAAGKPRPTVRWLRN-GEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKHGT 403
Query: 281 VSASGYLTVYD-PPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
+ AS L V P L+P + G C P+ + WS T I
Sbjct: 404 IYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWS---KGTEILV 460
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
SR T DG L I + ++D C A N+ G + G L+V R
Sbjct: 461 NSSR----VTVTPDGT--LIIRNISRSDE-GKYTCFAENFMGKANSTGILSV-----RDA 508
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
IT PS+ + + C A P + + + + + + G +
Sbjct: 509 TKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWT----LDDFPIDFDKPGGHYRRTN 564
Query: 458 DKSDSGTYTCV-ASSRHG-KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515
K G T + A RHG KY +VDS R PGPP + ++
Sbjct: 565 VKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGP-----PGPPGGVVVRDI 619
Query: 516 TDTSVTLSWSQ 526
DT++ LSWS+
Sbjct: 620 GDTTIQLSWSR 630
Score = 35.1 bits (77), Expect = 1.5
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
++ L TKY + + + G S S A T+ P PP NI + +++++ +KW
Sbjct: 875 VSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNIS-WTFSSSSLSIKWD 933
Query: 754 PPELQLQNGIITGYNVV 770
P +TGY ++
Sbjct: 934 PVVPFRNESAVTGYKML 950
>X67734-1|CAA47963.1| 1040|Homo sapiens transient axonal
glycoprotein protein.
Length = 1040
Score = 169 bits (412), Expect = 4e-41
Identities = 140/492 (28%), Positives = 209/492 (42%), Gaps = 42/492 (8%)
Query: 12 PYIIEQPLDVTV---ARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67
P +QPL V + + L CRA SP RW G + + R L G L
Sbjct: 37 PVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLV 96
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ T + DAGVY C A+N GT SR A L L+E + E + ++ +G V+L
Sbjct: 97 IMNPTKAQ---DAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVML 153
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNA 185
C PP P + W N D R H V GNL I +D G Y C+A +
Sbjct: 154 PCNPPAHYPGLSYRWLLNEFPNFIPTDGR-HFVSQTTGNLYIARTNASDLGNYSCLATSH 212
Query: 186 A--GTRE--SAIATLKIHIKPYLITGPE-------DVVAQTGSSVTFQCRVGGDPLPDVL 234
T+ S A L + + + P + A G VT +C G+P+P +
Sbjct: 213 MDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIK 272
Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
WR+ G L + +L++ +V DEG Y CEAENS G + G + V P
Sbjct: 273 WRKVDGS----LSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPE 328
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+ + G+ R+ C A G+P PT+ W G P S+++ A +
Sbjct: 329 WLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGE-----PLASQNRVEVLAGDLRFS 383
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-- 412
L++ D+ C A N G+ + +L V + P P + +P
Sbjct: 384 KLSLEDS------GMYQCVAENKHGTIYASAELAVQA----LAPDFRLNPVRRLIPAARG 433
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
+ PC P+ ++ W E L+ + R VT DGTL+++++ +SD G YTC A +
Sbjct: 434 GEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENF 493
Query: 473 HGKYVWSGALLV 484
GK +G L V
Sbjct: 494 MGKANSTGILSV 505
Score = 108 bits (259), Expect = 1e-22
Identities = 87/309 (28%), Positives = 136/309 (44%), Gaps = 22/309 (7%)
Query: 27 QPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYW 84
Q TL C A G+P P I+W K G + T L + F D G Y
Sbjct: 255 QQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSF---------EDEGTYE 305
Query: 85 CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
CEA NS G + + A + E+ ++ G + C G P P V W +
Sbjct: 306 CEAENSKGRDTVQGRIIVQA--QPEWLKVISDTEADIGSNLRWGCAAA-GKPRPTVRWLR 362
Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
NG+ L +R+ ++ G+L D+G YQC+A N GT ++ + P
Sbjct: 363 NGEPLA--SQNRVEVL-AGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDF 419
Query: 205 ITGPED--VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV 262
P + A G + C+ P VLW + + RV V DG+L + N+
Sbjct: 420 RLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEI-LVNSSRVTVTPDGTLIIRNI 478
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP-- 320
+DEG+Y+C AEN +G +++G L+V D I L+P+S ++ G+ C A+ P
Sbjct: 479 SRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTM 538
Query: 321 EPTMFWSVE 329
+ T W+++
Sbjct: 539 DLTFTWTLD 547
Score = 107 bits (257), Expect = 2e-22
Identities = 133/491 (27%), Positives = 192/491 (39%), Gaps = 58/491 (11%)
Query: 59 SILPAGGLFFLRATHGRVH------SDAGVYWCEATN----SYGTARSRNATLHVAVLRE 108
+ +P G F+ T G ++ SD G Y C AT+ S + S+ A L++A E
Sbjct: 175 NFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAA--E 232
Query: 109 EFRLE--------PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV 160
+ RL P + G V LEC G+P P + W+K +L S
Sbjct: 233 DTRLFAPSIKARFPAETYALVGQQVTLECFA-FGNPVPRIKWRKVDGSL-----SPQWTT 286
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
L I D G Y+C A N+ G R++ + + +P + D A GS++
Sbjct: 287 AEPTLQIPSVSFEDEGTYECEAENSKG-RDTVQGRIIVQAQPEWLKVISDTEADIGSNLR 345
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
+ C G P P V W R+ G RV+VL G LR + L D G Y C AEN G
Sbjct: 346 WGCAAAGKPRPTVRWLRN-GEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKHGT 403
Query: 281 VSASGYLTVYD-PPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
+ AS L V P L+P + G C P+ + WS T I
Sbjct: 404 IYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWS---KGTEILV 460
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
SR T DG L I + ++D C A N+ G + G L+V R
Sbjct: 461 NSSR----VTVTPDGT--LIIRNISRSDE-GKYTCFAENFMGKANSTGILSV-----RDA 508
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
IT PS+ + + C A P + + + + + + G +
Sbjct: 509 TKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWT----LDDFPIDFDKPGGHYRRTN 564
Query: 458 DKSDSGTYTCV-ASSRHG-KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515
K G T + A RHG KY +VDS R PGPP + ++
Sbjct: 565 VKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGP-----PGPPGGVVVRDI 619
Query: 516 TDTSVTLSWSQ 526
DT++ LSWS+
Sbjct: 620 GDTTIQLSWSR 630
Score = 35.1 bits (77), Expect = 1.5
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
++ L TKY + + + G S S A T+ P PP NI + +++++ +KW
Sbjct: 875 VSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNIS-WTFSSSSLSIKWD 933
Query: 754 PPELQLQNGIITGYNVV 770
P +TGY ++
Sbjct: 934 PVVPFRNESAVTGYKML 950
>BC129986-1|AAI29987.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 169 bits (412), Expect = 4e-41
Identities = 140/492 (28%), Positives = 209/492 (42%), Gaps = 42/492 (8%)
Query: 12 PYIIEQPLDVTV---ARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67
P +QPL V + + L CRA SP RW G + + R L G L
Sbjct: 37 PVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLV 96
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ T + DAGVY C A+N GT SR A L L+E + E + ++ +G V+L
Sbjct: 97 IMNPTKAQ---DAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVML 153
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNA 185
C PP P + W N D R H V GNL I +D G Y C+A +
Sbjct: 154 PCNPPAHYPGLSYRWLLNEFPNFIPTDGR-HFVSQTTGNLYIARTNASDLGNYSCLATSH 212
Query: 186 A--GTRE--SAIATLKIHIKPYLITGPE-------DVVAQTGSSVTFQCRVGGDPLPDVL 234
T+ S A L + + + P + A G VT +C G+P+P +
Sbjct: 213 MDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIK 272
Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
WR+ G L + +L++ +V DEG Y CEAENS G + G + V P
Sbjct: 273 WRKVDGS----LSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPE 328
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+ + G+ R+ C A G+P PT+ W G P S+++ A +
Sbjct: 329 WLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGE-----PLASQNRVEVLAGDLRFS 383
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-- 412
L++ D+ C A N G+ + +L V + P P + +P
Sbjct: 384 KLSLEDS------GMYQCVAENKHGTIYASAELAVQA----LAPDFRLNPVRRLIPAARG 433
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
+ PC P+ ++ W E L+ + R VT DGTL+++++ +SD G YTC A +
Sbjct: 434 GEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENF 493
Query: 473 HGKYVWSGALLV 484
GK +G L V
Sbjct: 494 MGKANSTGILSV 505
Score = 108 bits (259), Expect = 1e-22
Identities = 87/309 (28%), Positives = 136/309 (44%), Gaps = 22/309 (7%)
Query: 27 QPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYW 84
Q TL C A G+P P I+W K G + T L + F D G Y
Sbjct: 255 QQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSF---------EDEGTYE 305
Query: 85 CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
CEA NS G + + A + E+ ++ G + C G P P V W +
Sbjct: 306 CEAENSKGRDTVQGRIIVQA--QPEWLKVISDTEADIGSNLRWGCAAA-GKPRPTVRWLR 362
Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
NG+ L +R+ ++ G+L D+G YQC+A N GT ++ + P
Sbjct: 363 NGEPLA--SQNRVEVL-AGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDF 419
Query: 205 ITGPED--VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV 262
P + A G + C+ P VLW + + RV V DG+L + N+
Sbjct: 420 RLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEI-LVNSSRVTVTPDGTLIIRNI 478
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP-- 320
+DEG+Y+C AEN +G +++G L+V D I L+P+S ++ G+ C A+ P
Sbjct: 479 SRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTM 538
Query: 321 EPTMFWSVE 329
+ T W+++
Sbjct: 539 DLTFTWTLD 547
Score = 107 bits (257), Expect = 2e-22
Identities = 133/491 (27%), Positives = 192/491 (39%), Gaps = 58/491 (11%)
Query: 59 SILPAGGLFFLRATHGRVH------SDAGVYWCEATN----SYGTARSRNATLHVAVLRE 108
+ +P G F+ T G ++ SD G Y C AT+ S + S+ A L++A E
Sbjct: 175 NFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAA--E 232
Query: 109 EFRLE--------PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV 160
+ RL P + G V LEC G+P P + W+K +L S
Sbjct: 233 DTRLFAPSIKARFPAETYALVGQQVTLECFA-FGNPVPRIKWRKVDGSL-----SPQWTT 286
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
L I D G Y+C A N+ G R++ + + +P + D A GS++
Sbjct: 287 AEPTLQIPSVSFEDEGTYECEAENSKG-RDTVQGRIIVQAQPEWLKVISDTEADIGSNLR 345
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
+ C G P P V W R+ G RV+VL G LR + L D G Y C AEN G
Sbjct: 346 WGCAAAGKPRPTVRWLRN-GEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKHGT 403
Query: 281 VSASGYLTVYD-PPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
+ AS L V P L+P + G C P+ + WS T I
Sbjct: 404 IYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWS---KGTEILV 460
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
SR T DG L I + ++D C A N+ G + G L+V R
Sbjct: 461 NSSR----VTVTPDGT--LIIRNISRSDE-GKYTCFAENFMGKANSTGILSV-----RDA 508
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
IT PS+ + + C A P + + + + + + G +
Sbjct: 509 TKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWT----LDDFPIDFDKPGGHYRRTN 564
Query: 458 DKSDSGTYTCV-ASSRHG-KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515
K G T + A RHG KY +VDS R PGPP + ++
Sbjct: 565 VKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGP-----PGPPGGVVVRDI 619
Query: 516 TDTSVTLSWSQ 526
DT++ LSWS+
Sbjct: 620 GDTTIQLSWSR 630
Score = 35.1 bits (77), Expect = 1.5
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
++ L TKY + + + G S S A T+ P PP NI + +++++ +KW
Sbjct: 875 VSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNIS-WTFSSSSLSIKWD 933
Query: 754 PPELQLQNGIITGYNVV 770
P +TGY ++
Sbjct: 934 PVVPFRNESAVTGYKML 950
>AL583832-3|CAI15288.1| 1040|Homo sapiens contactin 2 (axonal)
protein.
Length = 1040
Score = 169 bits (412), Expect = 4e-41
Identities = 140/492 (28%), Positives = 209/492 (42%), Gaps = 42/492 (8%)
Query: 12 PYIIEQPLDVTV---ARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67
P +QPL V + + L CRA SP RW G + + R L G L
Sbjct: 37 PVFEDQPLSVLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLEPGSRHQLVGGNLV 96
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ T + DAGVY C A+N GT SR A L L+E + E + ++ +G V+L
Sbjct: 97 IMNPTKAQ---DAGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVML 153
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNA 185
C PP P + W N D R H V GNL I +D G Y C+A +
Sbjct: 154 PCNPPAHYPGLSYRWLLNEFPNFIPTDGR-HFVSQTTGNLYIARTNASDLGNYSCLATSH 212
Query: 186 A--GTRE--SAIATLKIHIKPYLITGPE-------DVVAQTGSSVTFQCRVGGDPLPDVL 234
T+ S A L + + + P + A G VT +C G+P+P +
Sbjct: 213 MDFSTKSVFSKFAQLNLAAEDTRLFAPSIKARFPAETYALVGQQVTLECFAFGNPVPRIK 272
Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
WR+ G L + +L++ +V DEG Y CEAENS G + G + V P
Sbjct: 273 WRKVDGS----LSPQWTTAEPTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQAQPE 328
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+ + G+ R+ C A G+P PT+ W G P S+++ A +
Sbjct: 329 WLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGE-----PLASQNRVEVLAGDLRFS 383
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK-- 412
L++ D+ C A N G+ + +L V + P P + +P
Sbjct: 384 KLSLEDS------GMYQCVAENKHGTIYASAELAVQA----LAPDFRLNPVRRLIPAARG 433
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
+ PC P+ ++ W E L+ + R VT DGTL+++++ +SD G YTC A +
Sbjct: 434 GEILIPCQPRAAPKAVVLWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENF 493
Query: 473 HGKYVWSGALLV 484
GK +G L V
Sbjct: 494 MGKANSTGILSV 505
Score = 108 bits (259), Expect = 1e-22
Identities = 87/309 (28%), Positives = 136/309 (44%), Gaps = 22/309 (7%)
Query: 27 QPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYW 84
Q TL C A G+P P I+W K G + T L + F D G Y
Sbjct: 255 QQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIPSVSF---------EDEGTYE 305
Query: 85 CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
CEA NS G + + A + E+ ++ G + C G P P V W +
Sbjct: 306 CEAENSKGRDTVQGRIIVQA--QPEWLKVISDTEADIGSNLRWGCAAA-GKPRPTVRWLR 362
Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
NG+ L +R+ ++ G+L D+G YQC+A N GT ++ + P
Sbjct: 363 NGEPLA--SQNRVEVL-AGDLRFSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDF 419
Query: 205 ITGPED--VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV 262
P + A G + C+ P VLW + + RV V DG+L + N+
Sbjct: 420 RLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWSKGTEI-LVNSSRVTVTPDGTLIIRNI 478
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP-- 320
+DEG+Y+C AEN +G +++G L+V D I L+P+S ++ G+ C A+ P
Sbjct: 479 SRSDEGKYTCFAENFMGKANSTGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTM 538
Query: 321 EPTMFWSVE 329
+ T W+++
Sbjct: 539 DLTFTWTLD 547
Score = 107 bits (257), Expect = 2e-22
Identities = 133/491 (27%), Positives = 192/491 (39%), Gaps = 58/491 (11%)
Query: 59 SILPAGGLFFLRATHGRVH------SDAGVYWCEATN----SYGTARSRNATLHVAVLRE 108
+ +P G F+ T G ++ SD G Y C AT+ S + S+ A L++A E
Sbjct: 175 NFIPTDGRHFVSQTTGNLYIARTNASDLGNYSCLATSHMDFSTKSVFSKFAQLNLAA--E 232
Query: 109 EFRLE--------PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV 160
+ RL P + G V LEC G+P P + W+K +L S
Sbjct: 233 DTRLFAPSIKARFPAETYALVGQQVTLECFA-FGNPVPRIKWRKVDGSL-----SPQWTT 286
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
L I D G Y+C A N+ G R++ + + +P + D A GS++
Sbjct: 287 AEPTLQIPSVSFEDEGTYECEAENSKG-RDTVQGRIIVQAQPEWLKVISDTEADIGSNLR 345
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
+ C G P P V W R+ G RV+VL G LR + L D G Y C AEN G
Sbjct: 346 WGCAAAGKPRPTVRWLRN-GEPLASQNRVEVLA-GDLRFSKLSLEDSGMYQCVAENKHGT 403
Query: 281 VSASGYLTVYD-PPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
+ AS L V P L+P + G C P+ + WS T I
Sbjct: 404 IYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQPRAAPKAVVLWS---KGTEILV 460
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
SR T DG L I + ++D C A N+ G + G L+V R
Sbjct: 461 NSSR----VTVTPDGT--LIIRNISRSDE-GKYTCFAENFMGKANSTGILSV-----RDA 508
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
IT PS+ + + C A P + + + + + + G +
Sbjct: 509 TKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWT----LDDFPIDFDKPGGHYRRTN 564
Query: 458 DKSDSGTYTCV-ASSRHG-KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515
K G T + A RHG KY +VDS R PGPP + ++
Sbjct: 565 VKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGP-----PGPPGGVVVRDI 619
Query: 516 TDTSVTLSWSQ 526
DT++ LSWS+
Sbjct: 620 GDTTIQLSWSR 630
Score = 35.1 bits (77), Expect = 1.5
Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 1/77 (1%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
++ L TKY + + + G S S A T+ P PP NI + +++++ +KW
Sbjct: 875 VSGLHPNTKYHVTVRAYNRAGTGPASPSANATTMKPPPRRPPGNIS-WTFSSSSLSIKWD 933
Query: 754 PPELQLQNGIITGYNVV 770
P +TGY ++
Sbjct: 934 PVVPFRNESAVTGYKML 950
>U72391-1|AAC51287.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 168 bits (409), Expect = 9e-41
Identities = 186/730 (25%), Positives = 288/730 (39%), Gaps = 84/730 (11%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +EP S +G +V+L C P P + WKK+G L D R L+ G+L I +
Sbjct: 55 FLVEPVDTLSVRGSSVILNC-SAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113
Query: 170 A-----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
+ D G YQC+A + GT S A L + P + PE G++ C
Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNC 173
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
V D +P V W ++ PL RV L G L + N D G Y C E+ G
Sbjct: 174 EVNADLVPFVRWEQN----RQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESG-GP 228
Query: 281 VSASGYLTVY---DPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
S + + DP I+ P+ + G C A+G P PT+ W
Sbjct: 229 PKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEE- 287
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
+ + + G + L I+D ++D+ T C A N + + +LTV +
Sbjct: 288 -----ALDTESSERLVLLAGGS-LEISDVTEDDA-GTYFCIADNGNETIEAQAELTVQAQ 340
Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
P P+N VF C P P + W G+ +I + + + L
Sbjct: 341 -----PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNL 395
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
+ L KSD G Y C+A + G +GA L+ P A LP P +
Sbjct: 396 QVLGLVKSDEGFYQCIAENDVGN-AQAGAQLIILEHAP-------ATTGPLPSAPRDVVA 447
Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572
V+ + L+W L Y V +++E ++ S +
Sbjct: 448 SLVSTRFIKLTWRTPASDPHGDNLTYSV-FYTKEGIARERVENTS--------HPGEMQV 498
Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILT 632
+++L+P Y+F V +N HG SG S S + V G + R +
Sbjct: 499 TIQNLMPATVYIFRVMAQNKHG-SGES--SAPLRVETQPEVQLPGP----APNLRAYAAS 551
Query: 633 DHIVELIEATPIDSKTIKLMWEILNF--YYLEGLFIYFRPLDNITIEYEMKTILHSNDVS 690
+ + TP+ EI N+ YY+E + D E ++ HS ++
Sbjct: 552 PTSITVTWETPVSGN-----GEIQNYKLYYME------KGTDK---EQDVDVSSHSYTIN 597
Query: 691 GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
G L+KYT+Y F ++ + K G + +TL DVP P N+ + + N+ ++ +
Sbjct: 598 G-----LKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMI 652
Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
W PP QNG ITGY + + KS V S ++ L G Y+ ++
Sbjct: 653 HWQPPAPATQNGQITGYKIRYR---KASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRV 709
Query: 811 AAETIIGLGP 820
AA TI G GP
Sbjct: 710 AALTINGTGP 719
Score = 162 bits (393), Expect = 8e-39
Identities = 144/569 (25%), Positives = 232/569 (40%), Gaps = 45/569 (7%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLR 70
Y + +P+D R LNC A PSP I W K G + VSD R +LP G LF
Sbjct: 54 YFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113
Query: 71 ATHGRVHS-DAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
H + + D G Y C AT S GT SR A L VA L F +PE G+ +L
Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGL-PRFTSQPEPSSVYAGNNAILN 172
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
C P V W++N Q LL D R+ + G LVI +A + D G Y+C+ +
Sbjct: 173 C-EVNADLVPFVRWEQNRQPLLLD--DRVIKLPSGMLVISNATEGDGGLYRCVVESGGPP 229
Query: 189 RESAIATLKIHIKPYLITG------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
+ S LK+ P +I+ P +V G V C G P P + W ++
Sbjct: 230 KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL 289
Query: 243 NMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
+ R+ +L GSL + +V D G Y C A+N + A LTV P P +
Sbjct: 290 DTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTN 349
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ F C TG+P PT+ W G+ ++ P Y + VL + +
Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGD--MVIP----SDYFKIVKEHNLQVLGLVKS 403
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT- 420
D+ + C A N G++ +L + + + P + + S T
Sbjct: 404 DEGFYQ----CIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTW 459
Query: 421 AICTPEP-----IIAWYFEGEALIQNHRRNVTNDGTL--VLKDLDKSDSGTYTCVASSRH 473
+P + ++ E + + N ++ G + +++L + + +A ++H
Sbjct: 460 RTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKH 519
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533
G S L V++ P + LPGP + + TS+T++W + G+
Sbjct: 520 GSGESSAPLRVET--QPEV---------QLPGPAPNLRAYAASPTSITVTW-ETPVSGNG 567
Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVV 562
I Y++ + T + +S + +
Sbjct: 568 EIQNYKLYYMEKGTDKEQDVDVSSHSYTI 596
Score = 135 bits (326), Expect = 1e-30
Identities = 190/826 (23%), Positives = 326/826 (39%), Gaps = 74/826 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P QP +V A LNC P +RW + ++ D LP+G L A
Sbjct: 152 PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNA 211
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLRE-EFRLEPESKQSAQGDTVV 126
T G D G+Y C + S L V V+ + F +P G VV
Sbjct: 212 TEG----DGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVV 267
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C+ G P P + W KN + L + R+ L+ GG+L I D + DAG Y CIA N
Sbjct: 268 LPCV-ASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGN 326
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
T E A A L + +P + P ++ A + F+C V G P P V W ++ G +P
Sbjct: 327 ETIE-AQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKN-GDMVIPS 384
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSV-N 303
K++ + +L++ ++ +DEG Y C AEN VG A L + + P + P++ +
Sbjct: 385 DYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRD 444
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIF--PGMSRDKYHATAVFDGVTVLTINDT 361
V + V+ T R + ++ + G++R++ T+ G +TI
Sbjct: 445 VVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTS-HPGEMQVTI--- 500
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
+N T+ V A + G+ + + P + GP+ +++ A P +
Sbjct: 501 -QNLMPATVYIFRV-MAQNKHGSGESSAPLRVETQPEVQLPGPAPN---LRAYAASPTSI 555
Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
T E ++ G IQN++ GT +D+D S S +YT ++ +Y S
Sbjct: 556 TVTWETPVS----GNGEIQNYKLYYMEKGTDKEQDVDVS-SHSYTINGLKKYTEY--SFR 608
Query: 482 LLVDSPINPNIHFFRAA--DVSSLPGPPTKPITHNVTDT-SVTLSWS-QNNKIGSSSILG 537
++ + P + A +S +P + ++ V ++ S+ + W + I G
Sbjct: 609 VVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITG 668
Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
Y++ + + + + T G Q +++ L G Y F V ++G
Sbjct: 669 YKIR-YRKASRKSDVTETLVSG--------TQLSQLIEGLDRGTEYNFRVAALT---ING 716
Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN 657
P +D ++ + L E + L IV + TP +++ I +
Sbjct: 717 TGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIV--VSWTPPENQNIVVRG---- 770
Query: 658 FYYLEGLFIYFRPLDNITIEYEMKTILHSN-DVSGFEITSLRKYTKYEFFLIPFYKKFEG 716
Y G I I ++Y+ + N D S + +L+ + IP Y+
Sbjct: 771 --YAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEG-IPLYESAVT 827
Query: 717 KPS-----------NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
+P N+ D P PP+ ++ IL+ T+ + W+ L I
Sbjct: 828 RPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITD 887
Query: 766 GYNVVVNW-LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
V W ++PAN N T S ++T L Y +
Sbjct: 888 SRYYTVRWKTNIPANTKYKNANAT---TLSYLVTGLKPNTLYEFSV 930
Score = 79.0 bits (186), Expect = 1e-13
Identities = 81/301 (26%), Positives = 127/301 (42%), Gaps = 20/301 (6%)
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
A + +S A+++ Y + P D ++ GSSV C +P P + W++
Sbjct: 33 AARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTF 92
Query: 242 GNMPL-GRVKVLDDGSLRLDNVILA-----DEGEYSCEAE-NSVGA-VSASGYLTVYDPP 293
N+ R ++L DGSL + NV+ + DEG Y C A S+G +S + L V P
Sbjct: 93 LNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLP 152
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
P +V +GN A C P + W E NR P + D+ + G+
Sbjct: 153 RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRW--EQNRQ---PLLLDDR--VIKLPSGM 205
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIK 412
V++ N T+ + V + S +L V D + ++ PS I
Sbjct: 206 LVIS-NATEGDGGLYRCVVESGGPPKYS-DEVELKVLPDPEVISDLVFLKQPSPLVRVIG 263
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
V PC A P P I W EAL + R + G+L + D+ + D+GTY C+A
Sbjct: 264 QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIAD 323
Query: 471 S 471
+
Sbjct: 324 N 324
Score = 46.0 bits (104), Expect = 8e-04
Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLK 751
+T L+ T YEF ++ + S + T + VP PP ++ + T+ +
Sbjct: 917 VTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVN 976
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
W PP NG ITGY ++ DV A I V + + LT Y +I
Sbjct: 977 WQPPSEA--NGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQ 1033
Query: 812 AETIIGLGPFSQKVYF 827
A G+GP S+ V F
Sbjct: 1034 ARNSKGMGPMSEAVQF 1049
>BC117161-1|AAI17162.1| 1461|Homo sapiens neogenin homolog 1
(chicken) protein.
Length = 1461
Score = 168 bits (409), Expect = 9e-41
Identities = 186/730 (25%), Positives = 288/730 (39%), Gaps = 84/730 (11%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +EP S +G +V+L C P P + WKK+G L D R L+ G+L I +
Sbjct: 55 FLVEPVDTLSVRGSSVILNC-SAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113
Query: 170 A-----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
+ D G YQC+A + GT S A L + P + PE G++ C
Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNNAILNC 173
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
V D +P V W ++ PL RV L G L + N D G Y C E+ G
Sbjct: 174 EVNADLVPFVRWEQN----RQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESG-GP 228
Query: 281 VSASGYLTVY---DPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
S + + DP I+ P+ + G C A+G P PT+ W
Sbjct: 229 PKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEE- 287
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
+ + + G + L I+D ++D+ T C A N + + +LTV +
Sbjct: 288 -----ALDTESSERLVLLAGGS-LEISDVTEDDA-GTYFCIADNGNETIEAQAELTVQAQ 340
Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
P P+N VF C P P + W G+ +I + + + L
Sbjct: 341 -----PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNL 395
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
+ L KSD G Y C+A + G +GA L+ P A LP P +
Sbjct: 396 QVLGLVKSDEGFYQCIAENDVGN-AQAGAQLIILEHAP-------ATTGPLPSAPRDVVA 447
Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572
V+ + L+W L Y V +++E ++ S +
Sbjct: 448 SLVSTRFIKLTWRTPASDPHGDNLTYSV-FYTKEGIARERVENTS--------HPGEMQV 498
Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILT 632
+++L+P Y+F V +N HG SG S S + V G + R +
Sbjct: 499 TIQNLMPATVYIFRVMAQNKHG-SGES--SAPLRVETQPEVQLPGP----APNLRAYAAS 551
Query: 633 DHIVELIEATPIDSKTIKLMWEILNF--YYLEGLFIYFRPLDNITIEYEMKTILHSNDVS 690
+ + TP+ EI N+ YY+E + D E ++ HS ++
Sbjct: 552 PTSITVTWETPVSGN-----GEIQNYKLYYME------KGTDK---EQDVDVSSHSYTIN 597
Query: 691 GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
G L+KYT+Y F ++ + K G + +TL DVP P N+ + + N+ ++ +
Sbjct: 598 G-----LKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMI 652
Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
W PP QNG ITGY + + KS V S ++ L G Y+ ++
Sbjct: 653 HWQPPAPATQNGQITGYKIRYR---KASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRV 709
Query: 811 AAETIIGLGP 820
AA TI G GP
Sbjct: 710 AALTINGTGP 719
Score = 162 bits (393), Expect = 8e-39
Identities = 144/569 (25%), Positives = 232/569 (40%), Gaps = 45/569 (7%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLR 70
Y + +P+D R LNC A PSP I W K G + VSD R +LP G LF
Sbjct: 54 YFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113
Query: 71 ATHGRVHS-DAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
H + + D G Y C AT S GT SR A L VA L F +PE G+ +L
Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGL-PRFTSQPEPSSVYAGNNAILN 172
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
C P V W++N Q LL D R+ + G LVI +A + D G Y+C+ +
Sbjct: 173 C-EVNADLVPFVRWEQNRQPLLLD--DRVIKLPSGMLVISNATEGDGGLYRCVVESGGPP 229
Query: 189 RESAIATLKIHIKPYLITG------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
+ S LK+ P +I+ P +V G V C G P P + W ++
Sbjct: 230 KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL 289
Query: 243 NMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
+ R+ +L GSL + +V D G Y C A+N + A LTV P P +
Sbjct: 290 DTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTN 349
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ F C TG+P PT+ W G+ ++ P Y + VL + +
Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGD--MVIP----SDYFKIVKEHNLQVLGLVKS 403
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT- 420
D+ + C A N G++ +L + + + P + + S T
Sbjct: 404 DEGFYQ----CIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTW 459
Query: 421 AICTPEP-----IIAWYFEGEALIQNHRRNVTNDGTL--VLKDLDKSDSGTYTCVASSRH 473
+P + ++ E + + N ++ G + +++L + + +A ++H
Sbjct: 460 RTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKH 519
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533
G S L V++ P + LPGP + + TS+T++W + G+
Sbjct: 520 GSGESSAPLRVET--QPEV---------QLPGPAPNLRAYAASPTSITVTW-ETPVSGNG 567
Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVV 562
I Y++ + T + +S + +
Sbjct: 568 EIQNYKLYYMEKGTDKEQDVDVSSHSYTI 596
Score = 135 bits (326), Expect = 1e-30
Identities = 190/826 (23%), Positives = 326/826 (39%), Gaps = 74/826 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P QP +V A LNC P +RW + ++ D LP+G L A
Sbjct: 152 PRFTSQPEPSSVYAGNNAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNA 211
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLRE-EFRLEPESKQSAQGDTVV 126
T G D G+Y C + S L V V+ + F +P G VV
Sbjct: 212 TEG----DGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVV 267
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C+ G P P + W KN + L + R+ L+ GG+L I D + DAG Y CIA N
Sbjct: 268 LPCV-ASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGN 326
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
T E A A L + +P + P ++ A + F+C V G P P V W ++ G +P
Sbjct: 327 ETIE-AQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKN-GDMVIPS 384
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSV-N 303
K++ + +L++ ++ +DEG Y C AEN VG A L + + P + P++ +
Sbjct: 385 DYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRD 444
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIF--PGMSRDKYHATAVFDGVTVLTINDT 361
V + V+ T R + ++ + G++R++ T+ G +TI
Sbjct: 445 VVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTS-HPGEMQVTI--- 500
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
+N T+ V A + G+ + + P + GP+ +++ A P +
Sbjct: 501 -QNLMPATVYIFRV-MAQNKHGSGESSAPLRVETQPEVQLPGPAPN---LRAYAASPTSI 555
Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
T E ++ G IQN++ GT +D+D S S +YT ++ +Y S
Sbjct: 556 TVTWETPVS----GNGEIQNYKLYYMEKGTDKEQDVDVS-SHSYTINGLKKYTEY--SFR 608
Query: 482 LLVDSPINPNIHFFRAA--DVSSLPGPPTKPITHNVTDT-SVTLSWS-QNNKIGSSSILG 537
++ + P + A +S +P + ++ V ++ S+ + W + I G
Sbjct: 609 VVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITG 668
Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
Y++ + + + + T G Q +++ L G Y F V ++G
Sbjct: 669 YKIR-YRKASRKSDVTETLVSG--------TQLSQLIEGLDRGTEYNFRVAALT---ING 716
Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN 657
P +D ++ + L E + L IV + TP +++ I +
Sbjct: 717 TGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIV--VSWTPPENQNIVVRG---- 770
Query: 658 FYYLEGLFIYFRPLDNITIEYEMKTILHSN-DVSGFEITSLRKYTKYEFFLIPFYKKFEG 716
Y G I I ++Y+ + N D S + +L+ + IP Y+
Sbjct: 771 --YAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEG-IPLYESAVT 827
Query: 717 KPS-----------NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
+P N+ D P PP+ ++ IL+ T+ + W+ L I
Sbjct: 828 RPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITD 887
Query: 766 GYNVVVNW-LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
V W ++PAN N T S ++T L Y +
Sbjct: 888 SRYYTVRWKTNIPANTKYKNANAT---TLSYLVTGLKPNTLYEFSV 930
Score = 79.0 bits (186), Expect = 1e-13
Identities = 81/301 (26%), Positives = 127/301 (42%), Gaps = 20/301 (6%)
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
A + +S A+++ Y + P D ++ GSSV C +P P + W++
Sbjct: 33 AARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTF 92
Query: 242 GNMPL-GRVKVLDDGSLRLDNVILA-----DEGEYSCEAE-NSVGA-VSASGYLTVYDPP 293
N+ R ++L DGSL + NV+ + DEG Y C A S+G +S + L V P
Sbjct: 93 LNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLP 152
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
P +V +GN A C P + W E NR P + D+ + G+
Sbjct: 153 RFTSQPEPSSVYAGNNAILNCEVNADLVPFVRW--EQNRQ---PLLLDDR--VIKLPSGM 205
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIK 412
V++ N T+ + V + S +L V D + ++ PS I
Sbjct: 206 LVIS-NATEGDGGLYRCVVESGGPPKYS-DEVELKVLPDPEVISDLVFLKQPSPLVRVIG 263
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
V PC A P P I W EAL + R + G+L + D+ + D+GTY C+A
Sbjct: 264 QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIAD 323
Query: 471 S 471
+
Sbjct: 324 N 324
Score = 46.0 bits (104), Expect = 8e-04
Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLK 751
+T L+ T YEF ++ + S + T + VP PP ++ + T+ +
Sbjct: 917 VTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVN 976
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
W PP NG ITGY ++ DV A I V + + LT Y +I
Sbjct: 977 WQPPSEA--NGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQ 1033
Query: 812 AETIIGLGPFSQKVYF 827
A G+GP S+ V F
Sbjct: 1034 ARNSKGMGPMSEAVQF 1049
>AK056557-1|BAB71216.1| 1252|Homo sapiens protein ( Homo sapiens
cDNA FLJ31995 fis, clone NT2RP7009236, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 1252
Score = 168 bits (409), Expect = 9e-41
Identities = 135/459 (29%), Positives = 211/459 (45%), Gaps = 39/459 (8%)
Query: 28 PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
P TL C+A G+P P++ W K G L+ + + + A G ++ + G ++G Y C A
Sbjct: 68 PVTLPCKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGG---EESGEYVCTA 124
Query: 88 TNSYGTARSR-NATLHV--AVLREEFRL---EPESKQSAQGDTVVLECLPPRGSPEPNVY 141
TN+ G A+ + T++V V ++ L +P G+ V L C + P P +
Sbjct: 125 TNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPC-EVKSLPPPIIT 183
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W K Q L+ R + G++ I + R +D+G Y C+A N AG A+ L +H+
Sbjct: 184 WAKETQ-LISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAINIAGNVTQAV-KLNVHVP 241
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLD-DGSLRL 259
P + GP+ + Q G V C G PLP + W S GG M + G V + DG+L +
Sbjct: 242 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITW--SKGGSTMLVDGEHHVSNPDGTLSI 299
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVA----RFTC 314
D +D G Y+C A N G L V +PP++ +L P VA F C
Sbjct: 300 DQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPC 359
Query: 315 TATGRPEPTMFWSVEGNR-TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
A G P+PT+ W G T PG+S + + T+L I D+ +C
Sbjct: 360 PAKGTPKPTIKWLHNGRELTGREPGIS--------ILEDGTLLVIASVTPYDN-GEYICV 410
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGP--SNQTLPIKSMAVFPCTAICTPEPIIAW 431
AVN AG++ + L V PP+I + +N ++ + + C TP PII W
Sbjct: 411 AVNEAGTTERKYNLKV-----HVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMW 465
Query: 432 YFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVA 469
Y + + ++ N+G ++ L D+G Y+C A
Sbjct: 466 YKDNVQVTESSTIQTVNNGRILKLFRATPEDAGRYSCKA 504
Score = 165 bits (401), Expect = 8e-40
Identities = 132/475 (27%), Positives = 213/475 (44%), Gaps = 39/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHG 74
EQ +V+V +Q L C G+PSP I WYK V V S T +++ L RAT
Sbjct: 436 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGRILKLFRATP- 494
Query: 75 RVHSDAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
DAG Y C+A N GT++ + + ++ F P V LEC
Sbjct: 495 ---EDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNF---PNEVSVVLNRDVALEC-Q 547
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRE 190
+G+P P+++W K+G+ L F GD + L+D G ++ +++AR+ D GRYQC NAAG +
Sbjct: 548 VKGTPFPDIHWFKDGKPL-FLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQA 606
Query: 191 SAIATLKIHIKPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
I L I+I P + G D+ S + +C G P+P + W + G M +
Sbjct: 607 KDI-KLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKD-GQPIMSSSQ 664
Query: 249 VKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NL-SPNSVNV 304
+D G L + ++D Y+C N G S ++ VY PP I NL +P + V
Sbjct: 665 ALYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQV 724
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+ C A G P P + W +G P + D A + +++ + D
Sbjct: 725 VIAHSLTLECKAAGNPSPILTWLKDG-----VPVKANDNIRIEAGGKKLEIMSAQEID-- 777
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ--TLPIKSMAVFPCTAI 422
R +C A + AG ++ ++ V PP I G + + ++ C
Sbjct: 778 --RGQYICVATSVAGEKEIKYEVDVL-----VPPAIEGGDETSYFIVMVNNLLELDCHVT 830
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGKY 476
+P P I W +G+ + + + +G LV+ S++G Y C+A++ G +
Sbjct: 831 GSPPPTIMWLKDGQLVDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDH 885
Score = 155 bits (376), Expect = 9e-37
Identities = 138/469 (29%), Positives = 195/469 (41%), Gaps = 34/469 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLR 70
P I P + V Q + C A G+P P I W KGG ++V H P G L +
Sbjct: 242 PKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLSIDQ 301
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVV 126
AT SDAG+Y C ATN GT + TLHV LEP + Q +
Sbjct: 302 AT----PSDAGIYTCVATNIAGTDET-EITLHVQEPPTVEDLEPPYNTTFQERVANQRIE 356
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C P +G+P+P + W NG+ L L DG LVI D G Y C+A N A
Sbjct: 357 FPC-PAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEA 415
Query: 187 GTRESAIATLKIHIKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
GT E LK+H+ P + + +V C V G P P ++W +
Sbjct: 416 GTTERKY-NLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKD-NVQVT 473
Query: 245 PLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNS 301
++ +++G L+L D G YSC+A N G + V PP+I PN
Sbjct: 474 ESSTIQTVNNGRILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNE 533
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V+V C G P P + W +G +F G + D VL + +
Sbjct: 534 VSVVLNRDVALECQVKGTPFPDIHWFKDGKP--LFLGDPN-----VELLDRGQVLHLKNA 586
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG--PSNQTLPIKSMAVFPC 419
+ND + C+ N AG KLT+ PP I G ++ ++ I S+ C
Sbjct: 587 RRND-KGRYQCTVSNAAGKQAKDIKLTIYI-----PPSIKGGNVTTDISVLINSLIKLEC 640
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTC 467
P P I WY +G+ ++ + + + G L + SDS TYTC
Sbjct: 641 ETRGLPMPAITWYKDGQPIMSSSQALYIDKGQYLHIPRAQVSDSATYTC 689
Score = 152 bits (369), Expect = 6e-36
Identities = 135/475 (28%), Positives = 209/475 (44%), Gaps = 40/475 (8%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHG 74
++P++++V + TL C P P I W K L+ + R + LP+G ++ T
Sbjct: 155 DKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGS---MKITET 211
Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRG 134
R SD+G+Y C A N G ++ L+V V + + P+ + G V + C +G
Sbjct: 212 RT-SDSGMYLCVAINIAGNV-TQAVKLNVHV-PPKIQRGPKHLKVQVGQRVDIPC-NAQG 267
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA 194
+P P + W K G T+L DG+ + D G L I A +DAG Y C+A N AGT E+ I
Sbjct: 268 TPLPVITWSKGGSTMLVDGEHHVSNPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEI- 325
Query: 195 TLKIHIKPYL--ITGPEDVVAQ---TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR- 248
TL + P + + P + Q + F C G P P + W + G GR
Sbjct: 326 TLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHN---GRELTGRE 382
Query: 249 --VKVLDDGSLR-LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
+ +L+DG+L + +V D GEY C A N G L V+ PP I NV
Sbjct: 383 PGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDKEQVTNVS 442
Query: 306 --SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
+ C G P P + W + + + V +G + T +
Sbjct: 443 VLLNQLTNLFCEVEGTPSPIIMWYKDNVQV-------TESSTIQTVNNGRILKLFRATPE 495
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSMAVFPCTAI 422
+ R + C A+N AG+S + V PP II TN P+ ++ + C
Sbjct: 496 DAGRYS--CKAINIAGTSQKYFNIDVLV----PPTIIGTNFPNEVSVVLNRDVALECQVK 549
Query: 423 CTPEPIIAWYFEGEAL-IQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
TP P I W+ +G+ L + + + + G L LK+ ++D G Y C S+ GK
Sbjct: 550 GTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAAGK 604
Score = 148 bits (358), Expect = 1e-34
Identities = 128/453 (28%), Positives = 193/453 (42%), Gaps = 34/453 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP P I W K G LV IL G + +V S+ G+Y C A N+
Sbjct: 825 LDCHVTGSPPPTIMWLKDGQLVDERDGFKILLNGRKLVI--AQAQV-SNTGLYRCMAANT 881
Query: 91 YGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G + T+HV + L + + V L+C+ G P P++ W K+ Q +
Sbjct: 882 AGDHKEEFEVTVHVPPTIKSSGLS--ERVVVKYKPVALQCIA-NGIPNPSITWLKDDQPV 938
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ G L I DAGRY C+A NAAG + I L +H P L +
Sbjct: 939 NTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQ-LHVHEPPSLEDAGK 997
Query: 210 --DVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP-LGRVKVLDDGSLRLDNV 262
+ + V +C+ G+P+P + W R +G +M L R +++D +++
Sbjct: 998 MLNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIID-----IESA 1052
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
++D G Y C A NS GA L V+ PSI+ S N V V N R C A G P P
Sbjct: 1053 QISDAGIYKCVAINSAGATELFYSLQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAP 1112
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W +G+ F + V G +L + +D+ C AVN AG
Sbjct: 1113 SLTWLKDGSPVSSFS-------NGLQVLSGGRILALTSAQISDT-GRYTCVAVNAAGEKQ 1164
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
L V PP I N ++ I C + P P + W +G L++
Sbjct: 1165 RDIDLRV-----YVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKDGHPLLKKP 1219
Query: 443 RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHG 474
+++ N L ++D D+G YTC A++ G
Sbjct: 1220 GLSISENRSVLKIEDAQVQDTGRYTCEATNVAG 1252
Score = 144 bits (350), Expect = 1e-33
Identities = 122/464 (26%), Positives = 198/464 (42%), Gaps = 26/464 (5%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
PL+ V TL C+A G+PSP + W K GV V ++ + I G + +
Sbjct: 719 PLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKLEIMSAQ---E 775
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
D G Y C AT+ G + + E E + + L+C GSP
Sbjct: 776 IDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDC-HVTGSPP 834
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P + W K+GQ L+ + D L++G LVI A+ ++ G Y+C+A N AG + +
Sbjct: 835 PTIMWLKDGQ-LVDERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKEEFE-VT 892
Query: 198 IHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256
+H+ P + +G + V V QC G P P + W + N G +K+ G
Sbjct: 893 VHVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 952
Query: 257 -LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN--VESGNVARFT 313
L++ +L D G Y+C A N+ G L V++PPS+ + +N V N +
Sbjct: 953 VLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPSLEDAGKMLNETVLVSNPVQLE 1012
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
C A G P P + W + NR + G + + + ++ I +D+ C
Sbjct: 1013 CKAAGNPVPVITW-YKDNR--LLSGST-----SMTFLNRGQIIDIESAQISDA-GIYKCV 1063
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
A+N AG++ + L V P I+ + + + + C A P P + W
Sbjct: 1064 AINSAGATELFYSLQV-----HVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLK 1118
Query: 434 EGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+G + N + ++ L L SD+G YTCVA + G+
Sbjct: 1119 DGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGE 1162
Score = 139 bits (337), Expect = 5e-32
Identities = 108/365 (29%), Positives = 172/365 (47%), Gaps = 29/365 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V +++P L C A G P+P+I W K V + + I +G + + T + DAG
Sbjct: 909 VVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIAKT---LLEDAG 965
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ----GDTVVLECLPPRGSPE 137
Y C ATN+ G + ++ LHV E LE K + + V LEC G+P
Sbjct: 966 RYTCVATNAAGETQ-QHIQLHV---HEPPSLEDAGKMLNETVLVSNPVQLEC-KAAGNPV 1020
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATL 196
P + W K+ + L G + M ++ G ++ I+ A+ +DAG Y+C+A N+AG E +L
Sbjct: 1021 PVITWYKDNR--LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATE-LFYSL 1077
Query: 197 KIHIKPYLITGPEDVVA-QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
++H+ P I+G ++VA + V +C G P P + W + + ++VL G
Sbjct: 1078 QVHVAP-SISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGG 1136
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L L + ++D G Y+C A N+ G L VY PP+I +V+V C
Sbjct: 1137 RILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQAVELLC 1196
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ P PT+ W +G+ + PG+S + + +VL I D D+ C A
Sbjct: 1197 QSDAIPPPTLTWLKDGHPLLKKPGLS--------ISENRSVLKIEDAQVQDT-GRYTCEA 1247
Query: 375 VNYAG 379
N AG
Sbjct: 1248 TNVAG 1252
Score = 136 bits (329), Expect = 5e-31
Identities = 113/409 (27%), Positives = 174/409 (42%), Gaps = 30/409 (7%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
D G Y C A+N GT ++ ++ V VL + + + +G V L C G+P+P
Sbjct: 25 DGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIPVTLPC-KASGNPKP 81
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
+V W K G+ L+ ++ G+L + ++G Y C A N AG + + L +
Sbjct: 82 SVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQ-LTV 139
Query: 199 HIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
+++P + P ++ G VT C V P P + W + + R
Sbjct: 140 YVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHT 199
Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
L GS+++ +D G Y C A N G V+ + L V+ PP I P + V+ G
Sbjct: 200 FLPSGSMKITETRTSDSGMYLCVAINIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRV 259
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
C A G P P + WS G+ ++ D H + DG L+I+ +D+
Sbjct: 260 DIPCNAQGTPLPVITWSKGGSTMLV------DGEHHVSNPDG--TLSIDQATPSDA-GIY 310
Query: 371 VCSAVNYAGSSFVRGKLTVTSD---DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
C A N AG+ L V +D PP T + Q FPC A TP+P
Sbjct: 311 TCVATNIAGTDETEITLHVQEPPTVEDLEPPYNT---TFQERVANQRIEFPCPAKGTPKP 367
Query: 428 IIAWYFEGEALI-QNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474
I W G L + ++ DGT LV+ + D+G Y CVA + G
Sbjct: 368 TIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAG 416
Score = 131 bits (317), Expect = 1e-29
Identities = 94/321 (29%), Positives = 143/321 (44%), Gaps = 24/321 (7%)
Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
G+L I+ + D G Y C+A N AGT + + +H+ P + G + + G VT
Sbjct: 14 GSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLP 72
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
C+ G+P P V+W + + + DGSL + + + GEY C A N+ G
Sbjct: 73 CKASGNPKPSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAK 132
Query: 283 ASGYLTVYDPPSI-----NLS---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
LTVY P + LS P ++V +G C P P + W+ E +
Sbjct: 133 RKVQLTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQL 190
Query: 335 IFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
I P R + + + I +T +DS +C A+N AG+ KL V
Sbjct: 191 ISPFSPRHTFLPSG------SMKITETRTSDS-GMYLCVAINIAGNVTQAVKLNV----- 238
Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DGTLV 453
PP I GP + + + PC A TP P+I W G ++ + +V+N DGTL
Sbjct: 239 HVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTMLVDGEHHVSNPDGTLS 298
Query: 454 LKDLDKSDSGTYTCVASSRHG 474
+ SD+G YTCVA++ G
Sbjct: 299 IDQATPSDAGIYTCVATNIAG 319
Score = 111 bits (266), Expect = 2e-23
Identities = 77/263 (29%), Positives = 123/263 (46%), Gaps = 11/263 (4%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHS 78
L+ TV P L C+A G+P P I WYK L+ T + L G + + + S
Sbjct: 999 LNETVLVSNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQ---IS 1055
Query: 79 DAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G T + +HVA + V LEC RG P
Sbjct: 1056 DAGIYKCVAINSAGATELFYSLQVHVA---PSISGSNNMVAVVVNNPVRLEC-EARGIPA 1111
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P++ W K+G + + L G L + A+ +D GRY C+A NAAG ++ I L+
Sbjct: 1112 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDI-DLR 1170
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS- 256
+++ P ++ ++V +V C+ P P + W + G + + + ++ S
Sbjct: 1171 VYVPPNIMGEEQNVSVLISQAVELLCQSDAIPPPTLTWLKD-GHPLLKKPGLSISENRSV 1229
Query: 257 LRLDNVILADEGEYSCEAENSVG 279
L++++ + D G Y+CEA N G
Sbjct: 1230 LKIEDAQVQDTGRYTCEATNVAG 1252
Score = 80.2 bits (189), Expect = 4e-14
Identities = 68/246 (27%), Positives = 104/246 (42%), Gaps = 19/246 (7%)
Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308
+ V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++ G
Sbjct: 8 ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILSTIEGI 67
Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
C A+G P+P++ WS +G S K+ A A DG + + +
Sbjct: 68 PVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPGGEESG 118
Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVFPCTAI 422
VC+A N AG + + +LTV RP +Q P++ PC
Sbjct: 119 EYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVK 175
Query: 423 CTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P PII W E + + + R G++ + + SDSG Y CVA + G +
Sbjct: 176 SLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVAINIAGNVTQAVK 235
Query: 482 LLVDSP 487
L V P
Sbjct: 236 LNVHVP 241
Score = 66.5 bits (155), Expect = 5e-10
Identities = 57/177 (32%), Positives = 78/177 (44%), Gaps = 6/177 (3%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I V V + P L C A G P+P++ W K G V S ++ + +GG L
Sbjct: 1082 APSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGSPVSSFSNGLQVLSGGR-ILA 1140
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
T ++ SD G Y C A N+ G + R+ L V V E ++ V L C
Sbjct: 1141 LTSAQI-SDTGRYTCVAVNAAG-EKQRDIDLRVYV-PPNIMGEEQNVSVLISQAVELLC- 1196
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
P P + W K+G LL + + L I+DA+ D GRY C A N AG
Sbjct: 1197 QSDAIPPPTLTWLKDGHPLLKKPGLSIS-ENRSVLKIEDAQVQDTGRYTCEATNVAG 1252
Score = 34.7 bits (76), Expect = 2.0
Identities = 26/97 (26%), Positives = 49/97 (50%), Gaps = 3/97 (3%)
Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
L+QN V +DG+L ++ + D G YTCVAS+ G + +++V + P I +
Sbjct: 2 LLQNPYITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH--VLPTIQHGQQ 59
Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
+S++ G P + ++ WS+ ++ S+S
Sbjct: 60 I-LSTIEGIPVTLPCKASGNPKPSVIWSKKGELISTS 95
>U61262-1|AAB17263.1| 1461|Homo sapiens neogenin protein.
Length = 1461
Score = 168 bits (408), Expect = 1e-40
Identities = 186/730 (25%), Positives = 287/730 (39%), Gaps = 84/730 (11%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +EP S +G +V+L C P P + WKK+G L D R L+ G+L I +
Sbjct: 55 FLVEPVDTLSVRGSSVILNC-SAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113
Query: 170 A-----RQTDAGRYQCIAR-NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
+ D G YQC+A + GT S A L + P + PE G+ C
Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQPEPSSVYAGNGAILNC 173
Query: 224 RVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA 280
V D +P V W ++ PL RV L G L + N D G Y C E+ G
Sbjct: 174 EVNADLVPFVRWEQN----RQPLLLDDRVIKLPSGMLVISNATEGDGGLYRCVVESG-GP 228
Query: 281 VSASGYLTVY---DPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
S + + DP I+ P+ + G C A+G P PT+ W
Sbjct: 229 PKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEE- 287
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
+ + + G + L I+D ++D+ T C A N + + +LTV +
Sbjct: 288 -----ALDTESSERLVLLAGGS-LEISDVTEDDA-GTYFCIADNGNETIEAQAELTVQAQ 340
Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
P P+N VF C P P + W G+ +I + + + L
Sbjct: 341 -----PEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSDYFKIVKEHNL 395
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
+ L KSD G Y C+A + G +GA L+ P A LP P +
Sbjct: 396 QVLGLVKSDEGFYQCIAENDVGN-AQAGAQLIILEHAP-------ATTGPLPSAPRDVVA 447
Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572
V+ + L+W L Y V +++E ++ S +
Sbjct: 448 SLVSTRFIKLTWRTPASDPHGDNLTYSV-FYTKEGIARERVENTS--------HPGEMQV 498
Query: 573 VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILT 632
+++L+P Y+F V +N HG SG S S + V G + R +
Sbjct: 499 TIQNLMPATVYIFRVMAQNKHG-SGES--SAPLRVETQPEVQLPGP----APNLRAYAAS 551
Query: 633 DHIVELIEATPIDSKTIKLMWEILNF--YYLEGLFIYFRPLDNITIEYEMKTILHSNDVS 690
+ + TP+ EI N+ YY+E + D E ++ HS ++
Sbjct: 552 PTSITVTWETPVSGN-----GEIQNYKLYYME------KGTDK---EQDVDVSSHSYTIN 597
Query: 691 GFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHL 750
G L+KYT+Y F ++ + K G + +TL DVP P N+ + + N+ ++ +
Sbjct: 598 G-----LKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMI 652
Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
W PP QNG ITGY + + KS V S ++ L G Y+ ++
Sbjct: 653 HWQPPAPATQNGQITGYKIRYR---KASRKSDVTETLVSGTQLSQLIEGLDRGTEYNFRV 709
Query: 811 AAETIIGLGP 820
AA TI G GP
Sbjct: 710 AALTINGTGP 719
Score = 161 bits (391), Expect = 1e-38
Identities = 144/569 (25%), Positives = 232/569 (40%), Gaps = 45/569 (7%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLR 70
Y + +P+D R LNC A PSP I W K G + VSD R +LP G LF
Sbjct: 54 YFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISN 113
Query: 71 ATHGRVHS-DAGVYWCEAT-NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
H + + D G Y C AT S GT SR A L VA L F +PE G+ +L
Sbjct: 114 VVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGL-PRFTSQPEPSSVYAGNGAILN 172
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
C P V W++N Q LL D R+ + G LVI +A + D G Y+C+ +
Sbjct: 173 C-EVNADLVPFVRWEQNRQPLLLD--DRVIKLPSGMLVISNATEGDGGLYRCVVESGGPP 229
Query: 189 RESAIATLKIHIKPYLITG------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
+ S LK+ P +I+ P +V G V C G P P + W ++
Sbjct: 230 KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL 289
Query: 243 NMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
+ R+ +L GSL + +V D G Y C A+N + A LTV P P +
Sbjct: 290 DTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTN 349
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ F C TG+P PT+ W G+ ++ P Y + VL + +
Sbjct: 350 IYAHESMDIVFECEVTGKPTPTVKWVKNGD--MVIP----SDYFKIVKEHNLQVLGLVKS 403
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT- 420
D+ + C A N G++ +L + + + P + + S T
Sbjct: 404 DEGFYQ----CIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTW 459
Query: 421 AICTPEP-----IIAWYFEGEALIQNHRRNVTNDGTL--VLKDLDKSDSGTYTCVASSRH 473
+P + ++ E + + N ++ G + +++L + + +A ++H
Sbjct: 460 RTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMAQNKH 519
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533
G S L V++ P + LPGP + + TS+T++W + G+
Sbjct: 520 GSGESSAPLRVET--QPEV---------QLPGPAPNLRAYAASPTSITVTW-ETPVSGNG 567
Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVV 562
I Y++ + T + +S + +
Sbjct: 568 EIQNYKLYYMEKGTDKEQDVDVSSHSYTI 596
Score = 135 bits (326), Expect = 1e-30
Identities = 190/826 (23%), Positives = 326/826 (39%), Gaps = 74/826 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P QP +V A LNC P +RW + ++ D LP+G L A
Sbjct: 152 PRFTSQPEPSSVYAGNGAILNCEVNADLVPFVRWEQNRQPLLLDDRVIKLPSGMLVISNA 211
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLRE-EFRLEPESKQSAQGDTVV 126
T G D G+Y C + S L V V+ + F +P G VV
Sbjct: 212 TEG----DGGLYRCVVESGGPPKYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVV 267
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C+ G P P + W KN + L + R+ L+ GG+L I D + DAG Y CIA N
Sbjct: 268 LPCV-ASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGN 326
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
T E A A L + +P + P ++ A + F+C V G P P V W ++ G +P
Sbjct: 327 ETIE-AQAELTVQAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKN-GDMVIPS 384
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSV-N 303
K++ + +L++ ++ +DEG Y C AEN VG A L + + P + P++ +
Sbjct: 385 DYFKIVKEHNLQVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRD 444
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIF--PGMSRDKYHATAVFDGVTVLTINDT 361
V + V+ T R + ++ + G++R++ T+ G +TI
Sbjct: 445 VVASLVSTRFIKLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTS-HPGEMQVTI--- 500
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
+N T+ V A + G+ + + P + GP+ +++ A P +
Sbjct: 501 -QNLMPATVYIFRV-MAQNKHGSGESSAPLRVETQPEVQLPGPAPN---LRAYAASPTSI 555
Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
T E ++ G IQN++ GT +D+D S S +YT ++ +Y S
Sbjct: 556 TVTWETPVS----GNGEIQNYKLYYMEKGTDKEQDVDVS-SHSYTINGLKKYTEY--SFR 608
Query: 482 LLVDSPINPNIHFFRAA--DVSSLPGPPTKPITHNVTDT-SVTLSWS-QNNKIGSSSILG 537
++ + P + A +S +P + ++ V ++ S+ + W + I G
Sbjct: 609 VVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITG 668
Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
Y++ + + + + T G Q +++ L G Y F V ++G
Sbjct: 669 YKIR-YRKASRKSDVTETLVSG--------TQLSQLIEGLDRGTEYNFRVAALT---ING 716
Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN 657
P +D ++ + L E + L IV + TP +++ I +
Sbjct: 717 TGPATDWLSAETFESDLDETRVPEVPSSLHVRPLVTSIV--VSWTPPENQNIVVRG---- 770
Query: 658 FYYLEGLFIYFRPLDNITIEYEMKTILHSN-DVSGFEITSLRKYTKYEFFLIPFYKKFEG 716
Y G I I ++Y+ + N D S + +L+ + IP Y+
Sbjct: 771 --YAIGYGIGSPHAQTIKVDYKQRYYTIENLDPSSHYVITLKAFNNVGEG-IPLYESAVT 827
Query: 717 KPS-----------NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIIT 765
+P N+ D P PP+ ++ IL+ T+ + W+ L I
Sbjct: 828 RPHTDTSEVDLFVINAPYTPVPDPTPMMPPVGVQASILSHDTIRITWADNSLPKHQKITD 887
Query: 766 GYNVVVNW-LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
V W ++PAN N T S ++T L Y +
Sbjct: 888 SRYYTVRWKTNIPANTKYKNANAT---TLSYLVTGLKPNTLYEFSV 930
Score = 79.0 bits (186), Expect = 1e-13
Identities = 81/301 (26%), Positives = 127/301 (42%), Gaps = 20/301 (6%)
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
A + +S A+++ Y + P D ++ GSSV C +P P + W++
Sbjct: 33 AARSGSAPQSPGASIRTFTPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTF 92
Query: 242 GNMPL-GRVKVLDDGSLRLDNVILA-----DEGEYSCEAE-NSVGA-VSASGYLTVYDPP 293
N+ R ++L DGSL + NV+ + DEG Y C A S+G +S + L V P
Sbjct: 93 LNLVSDDRRQLLPDGSLFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLP 152
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
P +V +GN A C P + W E NR P + D+ + G+
Sbjct: 153 RFTSQPEPSSVYAGNGAILNCEVNADLVPFVRW--EQNRQ---PLLLDDR--VIKLPSGM 205
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIK 412
V++ N T+ + V + S +L V D + ++ PS I
Sbjct: 206 LVIS-NATEGDGGLYRCVVESGGPPKYS-DEVELKVLPDPEVISDLVFLKQPSPLVRVIG 263
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
V PC A P P I W EAL + R + G+L + D+ + D+GTY C+A
Sbjct: 264 QDVVLPCVASGLPTPTIKWMKNEEALDTESSERLVLLAGGSLEISDVTEDDAGTYFCIAD 323
Query: 471 S 471
+
Sbjct: 324 N 324
Score = 46.0 bits (104), Expect = 8e-04
Identities = 38/136 (27%), Positives = 57/136 (41%), Gaps = 5/136 (3%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILN--TTTVHLK 751
+T L+ T YEF ++ + S + T + VP PP ++ + T+ +
Sbjct: 917 VTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEGKPKTIIVN 976
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
W PP NG ITGY ++ DV A I V + + LT Y +I
Sbjct: 977 WQPPSEA--NGKITGY-IIYYSTDVNAEIHDWVIEPVVGNRLTHQIQELTLDTPYYFKIQ 1033
Query: 812 AETIIGLGPFSQKVYF 827
A G+GP S+ V F
Sbjct: 1034 ARNSKGMGPMSEAVQF 1049
>BC130619-1|AAI30620.1| 1100|Homo sapiens CNTN5 protein protein.
Length = 1100
Score = 167 bits (405), Expect = 3e-40
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 12 PYIIEQPLDV---TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
P +++P D+ T + + LNC G+P P+ RW + G + ++ G F
Sbjct: 99 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
+ ++ D+G Y C ATN+ G+ SR ATL A L + +G VVL
Sbjct: 159 I--SNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLM 216
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187
C PP SPE W N DSR + + GNL I + +D G Y C+ +N
Sbjct: 217 CSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVT 276
Query: 188 TRESAIATLKIHIKPYLITG----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+ ++ + G P V A G++V +C G+P+P + W +
Sbjct: 277 NARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK 336
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
G +P L + NV L D G Y C AENS G S G L VY P
Sbjct: 337 V--NGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 394
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
N ++SG+ R+ C ATG+P PT W G + SR + +G VL
Sbjct: 395 KLNDTQLDSGSPLRWECKATGKPRPTYRWLKNG---VPLSPQSR-----VEMVNG--VLM 444
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM-AV 416
I++ +++D+ C A N G+ + +L + + P N + K V
Sbjct: 445 IHNVNQSDA-GMYQCLAENKYGAIYASAELKILAS---APTFALNQLKKTIIVTKDQEVV 500
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
C +P+P I+W A+ +N R + DG+L + + KSD G Y C + G
Sbjct: 501 IECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560
Query: 477 VWSGALLVDSP 487
+L V P
Sbjct: 561 EIIASLSVKEP 571
Score = 119 bits (287), Expect = 6e-26
Identities = 98/336 (29%), Positives = 143/336 (42%), Gaps = 19/336 (5%)
Query: 1 MSDDYVTSGEAPYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59
+ +D V P I + P VT A+ + C A G+P P I W K + S
Sbjct: 289 LRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLR 348
Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
A L + ++ DAG+Y C A NS G S L V + Q
Sbjct: 349 KSQA----VLEIPNVQL-DDAGIYECRAENSRGK-NSFRGQLQVYTYPHWVE-KLNDTQL 401
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
G + EC G P P W KNG L SR+ +V+G L+I + Q+DAG YQ
Sbjct: 402 DSGSPLRWEC-KATGKPRPTYRWLKNGVPL--SPQSRVEMVNGV-LMIHNVNQSDAGMYQ 457
Query: 180 CIARNAAGTRESAIATLKIHIK-PYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
C+A N G ++ A LKI P + ++ V +C+ G P P + W+
Sbjct: 458 CLAENKYGAIYAS-AELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWK 516
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ R+ +L DGSLR+ N +DEG+Y C EN G+ L+V +P I
Sbjct: 517 KGDRAVRENK-RIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE 575
Query: 297 LSPNSVNVESGNVARFTCTA--TGRPEPTMFWSVEG 330
L+P + G C A + T +W+++G
Sbjct: 576 LTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKG 611
Score = 107 bits (258), Expect = 2e-22
Identities = 91/320 (28%), Positives = 135/320 (42%), Gaps = 27/320 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P+ +E+ D + P C+A G P P RW K GV +S R + G L
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV-PLSPQSRVEMVNGVLMI--- 445
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLEC 129
H SDAG+Y C A N YG + +A L + F L K + VV+EC
Sbjct: 446 -HNVNQSDAGMYQCLAENKYGAIYA-SAELKILASAPTFALNQLKKTIIVTKDQEVVIEC 503
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
P+GSP+P + WKK + + + R+ ++ G+L I +A ++D G+Y C N G+
Sbjct: 504 -KPQGSPKPTISWKKGDRAVR--ENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRSAG------- 240
E IA+L + + P+ G S+ C+ D DV W
Sbjct: 561 E-IIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEE 619
Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
GG+ R + L + N++L G Y C + + +VS L V PP P
Sbjct: 620 GGHFESIRAQA-SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPG---PPG 675
Query: 301 SVNVESGNVARFTCTATGRP 320
V VE + T T + P
Sbjct: 676 IVIVE--EITESTATLSWSP 693
>AB013803-1|BAA36580.2| 1026|Homo sapiens hNB-2s protein.
Length = 1026
Score = 167 bits (405), Expect = 3e-40
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 12 PYIIEQPLDV---TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
P +++P D+ T + + LNC G+P P+ RW + G + ++ G F
Sbjct: 25 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 84
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
+ ++ D+G Y C ATN+ G+ SR ATL A L + +G VVL
Sbjct: 85 I--SNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLM 142
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187
C PP SPE W N DSR + + GNL I + +D G Y C+ +N
Sbjct: 143 CSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVT 202
Query: 188 TRESAIATLKIHIKPYLITG----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+ ++ + G P V A G++V +C G+P+P + W +
Sbjct: 203 NARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK 262
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
G +P L + NV L D G Y C AENS G S G L VY P
Sbjct: 263 V--NGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 320
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
N ++SG+ R+ C ATG+P PT W G + SR + +G VL
Sbjct: 321 KLNDTQLDSGSPLRWECKATGKPRPTYRWLKNG---VPLSPQSR-----VEMVNG--VLM 370
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM-AV 416
I++ +++D+ C A N G+ + +L + + P N + K V
Sbjct: 371 IHNVNQSDA-GMYQCLAENKYGAIYASAELKILAS---APTFALNQLKKTIIVTKDQEVV 426
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
C +P+P I+W A+ +N R + DG+L + + KSD G Y C + G
Sbjct: 427 IECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 486
Query: 477 VWSGALLVDSP 487
+L V P
Sbjct: 487 EIIASLSVKEP 497
Score = 119 bits (287), Expect = 6e-26
Identities = 98/336 (29%), Positives = 143/336 (42%), Gaps = 19/336 (5%)
Query: 1 MSDDYVTSGEAPYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59
+ +D V P I + P VT A+ + C A G+P P I W K + S
Sbjct: 215 LRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLR 274
Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
A L + ++ DAG+Y C A NS G S L V + Q
Sbjct: 275 KSQA----VLEIPNVQL-DDAGIYECRAENSRGK-NSFRGQLQVYTYPHWVE-KLNDTQL 327
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
G + EC G P P W KNG L SR+ +V+G L+I + Q+DAG YQ
Sbjct: 328 DSGSPLRWEC-KATGKPRPTYRWLKNGVPL--SPQSRVEMVNGV-LMIHNVNQSDAGMYQ 383
Query: 180 CIARNAAGTRESAIATLKIHIK-PYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
C+A N G ++ A LKI P + ++ V +C+ G P P + W+
Sbjct: 384 CLAENKYGAIYAS-AELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWK 442
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ R+ +L DGSLR+ N +DEG+Y C EN G+ L+V +P I
Sbjct: 443 KGDRAVRENK-RIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE 501
Query: 297 LSPNSVNVESGNVARFTCTA--TGRPEPTMFWSVEG 330
L+P + G C A + T +W+++G
Sbjct: 502 LTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKG 537
Score = 107 bits (258), Expect = 2e-22
Identities = 91/320 (28%), Positives = 135/320 (42%), Gaps = 27/320 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P+ +E+ D + P C+A G P P RW K GV +S R + G L
Sbjct: 316 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV-PLSPQSRVEMVNGVLMI--- 371
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLEC 129
H SDAG+Y C A N YG + +A L + F L K + VV+EC
Sbjct: 372 -HNVNQSDAGMYQCLAENKYGAIYA-SAELKILASAPTFALNQLKKTIIVTKDQEVVIEC 429
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
P+GSP+P + WKK + + + R+ ++ G+L I +A ++D G+Y C N G+
Sbjct: 430 -KPQGSPKPTISWKKGDRAVR--ENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 486
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRSAG------- 240
E IA+L + + P+ G S+ C+ D DV W
Sbjct: 487 E-IIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEE 545
Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
GG+ R + L + N++L G Y C + + +VS L V PP P
Sbjct: 546 GGHFESIRAQA-SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPG---PPG 601
Query: 301 SVNVESGNVARFTCTATGRP 320
V VE + T T + P
Sbjct: 602 IVIVE--EITESTATLSWSP 619
>AB013802-1|BAA36579.2| 1100|Homo sapiens hNB-2 protein.
Length = 1100
Score = 167 bits (405), Expect = 3e-40
Identities = 136/491 (27%), Positives = 206/491 (41%), Gaps = 33/491 (6%)
Query: 12 PYIIEQPLDV---TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
P +++P D+ T + + LNC G+P P+ RW + G + ++ G F
Sbjct: 99 PVFVQEPDDIIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLIDGTFI 158
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
+ ++ D+G Y C ATN+ G+ SR ATL A L + +G VVL
Sbjct: 159 I--SNPSEAKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLM 216
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187
C PP SPE W N DSR + + GNL I + +D G Y C+ +N
Sbjct: 217 CSPPPHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGSYICLVKNTVT 276
Query: 188 TRESAIATLKIHIKPYLITG----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+ ++ + G P V A G++V +C G+P+P + W +
Sbjct: 277 NARVLSPPTPLTLRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMK 336
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
G +P L + NV L D G Y C AENS G S G L VY P
Sbjct: 337 V--NGYIPSKARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 394
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
N ++SG+ R+ C ATG+P PT W G + SR + +G VL
Sbjct: 395 KLNDTQLDSGSPLRWECKATGKPRPTYRWLKNG---VPLSPQSR-----VEMVNG--VLM 444
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM-AV 416
I++ +++D+ C A N G+ + +L + + P N + K V
Sbjct: 445 IHNVNQSDA-GMYQCLAENKYGAIYASAELKILAS---APTFALNQLKKTIIVTKDQEVV 500
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
C +P+P I+W A+ +N R + DG+L + + KSD G Y C + G
Sbjct: 501 IECKPQGSPKPTISWKKGDRAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560
Query: 477 VWSGALLVDSP 487
+L V P
Sbjct: 561 EIIASLSVKEP 571
Score = 119 bits (287), Expect = 6e-26
Identities = 98/336 (29%), Positives = 143/336 (42%), Gaps = 19/336 (5%)
Query: 1 MSDDYVTSGEAPYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59
+ +D V P I + P VT A+ + C A G+P P I W K + S
Sbjct: 289 LRNDGVMGEYEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLR 348
Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
A L + ++ DAG+Y C A NS G S L V + Q
Sbjct: 349 KSQA----VLEIPNVQL-DDAGIYECRAENSRGK-NSFRGQLQVYTYPHWVE-KLNDTQL 401
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
G + EC G P P W KNG L SR+ +V+G L+I + Q+DAG YQ
Sbjct: 402 DSGSPLRWEC-KATGKPRPTYRWLKNGVPL--SPQSRVEMVNGV-LMIHNVNQSDAGMYQ 457
Query: 180 CIARNAAGTRESAIATLKIHIK-PYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
C+A N G ++ A LKI P + ++ V +C+ G P P + W+
Sbjct: 458 CLAENKYGAIYAS-AELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWK 516
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ R+ +L DGSLR+ N +DEG+Y C EN G+ L+V +P I
Sbjct: 517 KGDRAVRENK-RIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIE 575
Query: 297 LSPNSVNVESGNVARFTCTA--TGRPEPTMFWSVEG 330
L+P + G C A + T +W+++G
Sbjct: 576 LTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKG 611
Score = 107 bits (258), Expect = 2e-22
Identities = 91/320 (28%), Positives = 135/320 (42%), Gaps = 27/320 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P+ +E+ D + P C+A G P P RW K GV +S R + G L
Sbjct: 390 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV-PLSPQSRVEMVNGVLMI--- 445
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLEC 129
H SDAG+Y C A N YG + +A L + F L K + VV+EC
Sbjct: 446 -HNVNQSDAGMYQCLAENKYGAIYA-SAELKILASAPTFALNQLKKTIIVTKDQEVVIEC 503
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
P+GSP+P + WKK + + + R+ ++ G+L I +A ++D G+Y C N G+
Sbjct: 504 -KPQGSPKPTISWKKGDRAVR--ENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 560
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRSAG------- 240
E IA+L + + P+ G S+ C+ D DV W
Sbjct: 561 E-IIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEE 619
Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
GG+ R + L + N++L G Y C + + +VS L V PP P
Sbjct: 620 GGHFESIRAQA-SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPG---PPG 675
Query: 301 SVNVESGNVARFTCTATGRP 320
V VE + T T + P
Sbjct: 676 IVIVE--EITESTATLSWSP 693
>AY310398-1|AAP75619.1| 2213|Homo sapiens sidekick-like protein 1
protein.
Length = 2213
Score = 165 bits (401), Expect = 8e-40
Identities = 214/823 (26%), Positives = 320/823 (38%), Gaps = 89/823 (10%)
Query: 22 TVARHQPATLNCRAGGS-PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
TV++ + A LN S P P + W++ G ++ +I L L T SDA
Sbjct: 201 TVSQGRAAILNLLPITSYPRPQVTWFREGHKIIPSNRIAITLENQLVILATTT----SDA 256
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLE--------PESKQS--AQGDTVVLECL 130
G Y+ +A N + +H+++ R+ E P +S A LEC+
Sbjct: 257 GAYYVQAVNEKNGENKTSPFIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECI 316
Query: 131 -PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
R + +V WK+NG + S +H G +L I + D G Y C A
Sbjct: 317 ASARPVEDLSVTWKRNGVRI----TSGLHSF-GRHLTISNPTSADTGPYVCEAALPGSAF 371
Query: 190 ESAIATLKIHI--KPYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSA-GGGNMP 245
E A AT + I PY PE + A+ +V C+ G PLP + W + A +
Sbjct: 372 EPARATAFLFIIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQ 431
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPNSVNV 304
R KVL G LR+ + D G + C A N G + YL V + P P V
Sbjct: 432 NPRYKVLASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTV 491
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G A C +G P+P + W E + I+ G R G+ + + D
Sbjct: 492 TDGMTAILRCEVSGAPKPAITWKRENH--ILASGSVRIPRFMLLESGGLQIAPVFIQDAG 549
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
+ C A N GS LTV + I + P + + + A C A
Sbjct: 550 N----YTCYAANTEGSLNASATLTVWNRTS-----IVHPPEDHVVIKGTTATLHCGATHD 600
Query: 425 PEPII--AWYFEGEALI--QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P + W + AL R V DG+L++ D G Y+C S G
Sbjct: 601 PRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMA 660
Query: 481 AL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539
L +++ P +P +L P +H +V LSW + G+S IL Y
Sbjct: 661 RLEVIELPHSP----------QNLLVSPNSSHSH-----AVVLSWVRPFD-GNSPILYYI 704
Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
VE LS N++P W V V T V L P TY F V N G
Sbjct: 705 VE------LSENSSP-----WKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQ 753
Query: 598 PSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN 657
S + + + ++ S V++ R N I+ + P E +
Sbjct: 754 YSAETSRLMLPEEPPSAPPKNIVASG---RTN---QSIMVQWQPPP----------ETEH 797
Query: 658 FYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK 717
L G + +R L + EY+ + I S +V+ +T L +T+YE + + G
Sbjct: 798 NGVLRGYILRYR-LAGLPGEYQQRNIT-SPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGV 855
Query: 718 PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
S + TL VP PP N++ +N+TT+ W+PP Q NGI GY ++ D P
Sbjct: 856 FSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAP 915
Query: 778 ANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
++V I H +TNL +Y + T G GP
Sbjct: 916 EAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGP 958
Score = 124 bits (300), Expect = 1e-27
Identities = 94/322 (29%), Positives = 142/322 (44%), Gaps = 16/322 (4%)
Query: 11 APYIIEQPLDVTV-ARHQPATLNCRAGGSPSP--AIRWYKGGVLVVSDTHRSILPAGGLF 67
AP I+ P + +V A TL C A P ++ W + GV + S H L
Sbjct: 292 APTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRITSGLHSF---GRHLT 348
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ-GDTV 125
T +D G Y CEA AT + ++ F EPES+ SA+ +TV
Sbjct: 349 ISNPTS----ADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRISAEVEETV 404
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
+ C G P P + W K+ ++ + R ++ G L IQ R D+G +QC A N
Sbjct: 405 DIGC-QAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIFQCFASNE 463
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS---AGGG 242
G ++ +I P P D G + +C V G P P + W+R G
Sbjct: 464 GGEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASG 523
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
++ + R +L+ G L++ V + D G Y+C A N+ G+++AS LTV++ SI P
Sbjct: 524 SVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDH 583
Query: 303 NVESGNVARFTCTATGRPEPTM 324
V G A C AT P ++
Sbjct: 584 VVIKGTTATLHCGATHDPRVSL 605
Score = 118 bits (285), Expect = 1e-25
Identities = 110/421 (26%), Positives = 185/421 (43%), Gaps = 34/421 (8%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGL 66
E PY +P ++ + + C+A G P P ++WYK + + + + +L +GGL
Sbjct: 384 EPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGL 443
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
+ D+G++ C A+N G ++ + L V + F P G T +
Sbjct: 444 RIQKLRP----EDSGIFQCFASNEGGEIQT-HTYLDVTNIAPVFTQRPVDTTVTDGMTAI 498
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH---LVDGGNLVIQDARQTDAGRYQCIAR 183
L C G+P+P + WK+ +L G R+ L++ G L I DAG Y C A
Sbjct: 499 LRC-EVSGAPKPAITWKRENH-ILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAA 556
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWRR-SAG 240
N G+ +A ATL + + ++ PED V G++ T C DP + +W++ +
Sbjct: 557 NTEGSL-NASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVA 615
Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----YDPPSIN 296
R+ V DGSL + D G+YSCE + G S L V + P ++
Sbjct: 616 LTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLL 675
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
+SPNS + V + G P +++ VE + S K H + V +T +
Sbjct: 676 VSPNSSH-SHAVVLSWVRPFDGN-SPILYYIVE-----LSENSSPWKVHLSNVGPEMTGV 728
Query: 357 TINDTDKNDSRNTIVCSAVNYAGS---SFVRGKLTVTSDDDRPPP--IITNGPSNQTLPI 411
T++ + VC AVN G S +L + + PP I+ +G +NQ++ +
Sbjct: 729 TVSGLTPARTYQFRVC-AVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMV 787
Query: 412 K 412
+
Sbjct: 788 Q 788
Score = 101 bits (243), Expect = 1e-20
Identities = 108/427 (25%), Positives = 162/427 (37%), Gaps = 40/427 (9%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
DAG Y C N G R + + VA + F + K +QG +L LP P P
Sbjct: 163 DAGFYRCVVRNRMGALLQRKSEVQVAYMGS-FMDTDQRKTVSQGRAAILNLLPITSYPRP 221
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY--QCIARNAAGTRESAIATL 196
V W + G ++ +R+ + LVI +DAG Y Q + + S L
Sbjct: 222 QVTWFREGHKII--PSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPFIHL 279
Query: 197 KIH--------IKPYLITGPEDVVAQTGSS-VTFQCRVGGDPLPD--VLWRRSAGGGNMP 245
I + P ++ P + GSS T +C P+ D V W+R+ G +
Sbjct: 280 SIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRN--GVRIT 337
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAE---NSVGAVSASGYLTVYDPPSINLSPNS- 301
G L + N AD G Y CEA ++ A+ +L + +PP P S
Sbjct: 338 SGLHSF--GRHLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESR 395
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
++ E C A G P PT+ W + I + +Y A G+ + +
Sbjct: 396 ISAEVEETVDIGCQAMGVPLPTLQWYKDA---ISISRLQNPRYKVLAS-GGLRIQKLRPE 451
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
D C A N G L VT+ P+ T P + T+ A+ C
Sbjct: 452 DSG----IFQCFASNEGGEIQTHTYLDVTNI----APVFTQRPVDTTVTDGMTAILRCEV 503
Query: 422 ICTPEPIIAWYFEGEAL----IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
P+P I W E L ++ R + G L + + D+G YTC A++ G
Sbjct: 504 SGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLN 563
Query: 478 WSGALLV 484
S L V
Sbjct: 564 ASATLTV 570
Score = 74.5 bits (175), Expect = 2e-12
Identities = 87/382 (22%), Positives = 155/382 (40%), Gaps = 37/382 (9%)
Query: 110 FRLEPESKQ-SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
F+ EP Q +G+ +VL CL P + + + + + + + +I
Sbjct: 106 FKTEPGLPQIHLEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKY--------IIP 157
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGG 227
++ DAG Y+C+ RN G + +++ ++ ++ T V+Q +++ +
Sbjct: 158 SLQKLDAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITS 217
Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV-GAVSASGY 286
P P V W R G +P R+ + + L + +D G Y +A N G S +
Sbjct: 218 YPRPQVTWFRE-GHKIIPSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGENKTSPF 276
Query: 287 L------TVYDP----PSINLSPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTII 335
+ V P P+I + P + +V +G+ C A+ RP + + + N I
Sbjct: 277 IHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRNGVRI 336
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
G+ H LTI++ D+ VC A GS+F + T
Sbjct: 337 TSGLHSFGRH----------LTISNPTSADT-GPYVCEAA-LPGSAFEPARATAFLFIIE 384
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGTLV 453
PP S + ++ C A+ P P + WY + ++ +QN R V G L
Sbjct: 385 PPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLR 444
Query: 454 LKDLDKSDSGTYTCVASSRHGK 475
++ L DSG + C AS+ G+
Sbjct: 445 IQKLRPEDSGIFQCFASNEGGE 466
Score = 66.5 bits (155), Expect = 5e-10
Identities = 53/187 (28%), Positives = 86/187 (45%), Gaps = 10/187 (5%)
Query: 637 ELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNIT-IEYEMKT-ILHSNDVSGFEI 694
E + A + S I L W + GL + ++ L ++ E ++ I+ N +
Sbjct: 1281 ENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALL 1340
Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ-TLDDVPDGPPINIEMFILNTTTVHLKWS 753
LRK+ YE ++ F + G PS + + T DD P GPP+ + + T+V + W
Sbjct: 1341 AGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAP-GPPVRLVFPEVRLTSVRIVWQ 1399
Query: 754 PPELQLQNGIITGYNVVVNWL-DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
PPE NGII GY + P + V + TV Q T+ T+L +Y +++A
Sbjct: 1400 PPE--EPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTA---TDLAPESAYIFRLSA 1454
Query: 813 ETIIGLG 819
+T G G
Sbjct: 1455 KTRQGWG 1461
Score = 58.4 bits (135), Expect = 1e-07
Identities = 49/187 (26%), Positives = 93/187 (49%), Gaps = 14/187 (7%)
Query: 639 IEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILH-SNDVSGFE---I 694
++ ++S TI+ +W ++ G+ ++ L E T++ + D G I
Sbjct: 876 VQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHI 935
Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754
T+L+K+T Y ++ F +G PS ++ T +D P G ++ + T++ + W
Sbjct: 936 TNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKP-GAVGHLSFTEILDTSLKVSWQE 994
Query: 755 PELQLQNGIITGYNVVVNWLDVPANKSMV--AINTTVHQATSLIMTNLTSGVSYSVQIAA 812
P L+ +NGIITGY ++W N S + +N+T H+ + L+S +Y++ +AA
Sbjct: 995 P-LE-KNGIITGYQ--ISWEVYGRNDSRLTHTLNSTTHEYK---IQGLSSLTTYTIDVAA 1047
Query: 813 ETIIGLG 819
T +G G
Sbjct: 1048 VTAVGTG 1054
Score = 58.4 bits (135), Expect = 1e-07
Identities = 83/336 (24%), Positives = 140/336 (41%), Gaps = 39/336 (11%)
Query: 504 PGPPTKPITHN--VTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
P PP + + VT S+ L W + G+S I + ++V RE PR W
Sbjct: 1477 PAPPRELLVPQAEVTARSLRLQWVPGSD-GASPIRYFTMQV--REL------PRGE--WQ 1525
Query: 562 VIARRV-HQ-THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTG 619
+ + H+ T VV L P +Y ++ N G S S +++VT D E G
Sbjct: 1526 TYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPG--EPPG 1583
Query: 620 VSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLE-----GLFIYFRPLDN- 673
++T + + + LI+ P +++ + + YY E G + L N
Sbjct: 1584 SVSATPHTTSSV------LIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNP 1637
Query: 674 ------ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTL 727
+T + KT+ S+ + E+T L+KY +YE + Y P+++ V +
Sbjct: 1638 IALXAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTA-YNIIGESPASAPVEVFV 1696
Query: 728 DDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
+ P P N+++ L + + + W PP + QNG I GY + W + + +
Sbjct: 1697 GEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYY-W-EADSQNETEKMK 1754
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
+ + NLTS Y V I+A G GP S
Sbjct: 1755 VLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKS 1790
Score = 53.2 bits (122), Expect = 5e-06
Identities = 44/182 (24%), Positives = 81/182 (44%), Gaps = 10/182 (5%)
Query: 639 IEATPIDSKTIKLMWEI----LNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI 694
++ TP+ + +++ W+ ++G IY+ D+ +MK + V +
Sbjct: 1708 VQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPV--VRL 1765
Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP 754
+L +TKY + F +G S+ + +T P G P + + +TT+++ W
Sbjct: 1766 KNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAP-GAPSFLAFSEITSTTLNVSWGE 1824
Query: 755 PELQLQNGIITGYNVVVNWL-DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
P NGI+ GY VV L V +V + + L + +LT GV+Y ++ A
Sbjct: 1825 PAAA--NGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQAR 1882
Query: 814 TI 815
TI
Sbjct: 1883 TI 1884
Score = 51.6 bits (118), Expect = 2e-05
Identities = 36/129 (27%), Positives = 59/129 (45%), Gaps = 4/129 (3%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
F I L ++ +YE + F G S +T + VP P N+ +++T + L
Sbjct: 1237 FTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLT 1296
Query: 752 WSPPELQLQNGIITGYNVVVNWLDV-PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
W+ Q QNG+I GY ++ D+ P +S + + S ++ L V Y +Q+
Sbjct: 1297 WTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRG---NHTQSALLAGLRKFVLYELQV 1353
Query: 811 AAETIIGLG 819
A T IG G
Sbjct: 1354 LAFTRIGNG 1362
Score = 50.0 bits (114), Expect = 5e-05
Identities = 34/139 (24%), Positives = 60/139 (43%), Gaps = 3/139 (2%)
Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTL-DDVPDGPPINIEMFILNTT 746
+++G ++ L Y+F + + G+ S L ++ P PP NI
Sbjct: 724 EMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQ 783
Query: 747 TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSY 806
++ ++W PP NG++ GY + +P N T + ++T+L Y
Sbjct: 784 SIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQ--RNITSPEVNYCLVTDLIIWTQY 841
Query: 807 SVQIAAETIIGLGPFSQKV 825
+Q+AA GLG FS+ V
Sbjct: 842 EIQVAAYNGAGLGVFSRAV 860
Score = 48.0 bits (109), Expect = 2e-04
Identities = 37/140 (26%), Positives = 57/140 (40%), Gaps = 3/140 (2%)
Query: 688 DVSGFEITSLRKYTKYEFFL--IPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745
D EI +L YT Y F + + PS SRV QTL PD P ++ + +
Sbjct: 1129 DAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPS-SRVIQTLQAPPDVAPTSVTVRTASE 1187
Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVS 805
T++ L+W P NG + + S VA + + L +
Sbjct: 1188 TSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWME 1247
Query: 806 YSVQIAAETIIGLGPFSQKV 825
Y +Q+ A +G GP+S+ V
Sbjct: 1248 YELQMQAFNAVGAGPWSEVV 1267
Score = 46.8 bits (106), Expect = 5e-04
Identities = 73/352 (20%), Positives = 133/352 (37%), Gaps = 32/352 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PGPP + + V TSV + W Q + + ILGYQ+ R S +T V +
Sbjct: 1378 PGPPVRLVFPEVRLTSVRIVW-QPPEEPNGIILGYQIAY--RLASSSPHTFTT----VEV 1430
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNS 623
V Q + L P Y+F + + G P E T ++
Sbjct: 1431 GATVRQ--FTATDLAPESAYIFRLSAKTRQGWGEPL----------------EATVITTE 1472
Query: 624 TEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTI 683
R + +V E T +++++L W + + + + E++ +
Sbjct: 1473 KRERPAPPRELLVPQAEVT---ARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSS 1529
Query: 684 LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGK-PSNSRVAQTLDDVPDGPPINIEMFI 742
S++ + + LR +T Y+ L + S + TL DVP PP ++
Sbjct: 1530 SISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATP 1589
Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802
T++V ++W PP + NG++ GY + L+ A A T+ +L LT+
Sbjct: 1590 HTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEA--KTLKNPIAL-XAELTA 1646
Query: 803 GVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGD 854
S+ ++ T K Y + +++ P + V + G+
Sbjct: 1647 QSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGE 1698
>AF491813-1|AAM09558.1| 2113|Homo sapiens Down syndrome cell adhesion
molecule 2 protein.
Length = 2113
Score = 164 bits (399), Expect = 1e-39
Identities = 207/832 (24%), Positives = 340/832 (40%), Gaps = 74/832 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I ++T + +NCR G P +I+WYK +L+ D HR ++ G L+
Sbjct: 565 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGT--LKL 621
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
T + D G Y C + S++ +HVAV E ++ G + + C+
Sbjct: 622 TDVQKGMDEGEYLCSVLIQPQLSISQS--VHVAVKVPPLIQPFEFPPASIGQLLYIPCVV 679
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G + W+K+GQ ++ + + +L I G Y CIA NAA T
Sbjct: 680 SSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAAT-V 738
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN------M 244
S L + + P + P + G + C V G P P V+W+ + G GN +
Sbjct: 739 SRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPV 798
Query: 245 PL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302
PL GR+++L + SL + +V+ D G Y C+A N VG +S S +LTV P I PN+
Sbjct: 799 PLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTT 858
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG----VTVLTI 358
G+ CTA G + W E T+I P R +A A D V+ L +
Sbjct: 859 IAIKGHAKELNCTARGERPIIIRW--EKGDTVIDP--DRVMRYAIATKDNGDEVVSTLKL 914
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
D+ DS C A+N G +LTV D PP + +++ ++ F
Sbjct: 915 KPADRGDS-VFFSCHAINSYGEDRGLIQLTVQEPPD-PPELEIREVKARSMNLRWTQRFD 972
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+I T I + RN++ N +V DL + + + ++ G+
Sbjct: 973 GNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIV--DLHPASVYSIRMYSFNKIGR 1030
Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSS 534
S L + + + ++ GPP VT S+ ++W K + +
Sbjct: 1031 SEPSKELTI------------STEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGV 1078
Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
I GYQ+ RE G+N V + Y + +L Y +V+ N G
Sbjct: 1079 IRGYQIGY--RENSPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 1133
Query: 595 LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
+GPS + T +D S R +T + + + P S
Sbjct: 1134 -TGPSSSEINATTLEDVPS-------QPPENVRALSITSDVAVISWSEPPRS-------- 1177
Query: 655 ILNFYYLEGLFIYFRPLDNITIEY-EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKK 713
LN L+G + F L + E+ EM+ I + + E+ + K+T Y ++ + +
Sbjct: 1178 TLN-GVLKGYRVIFWSL-YVDGEWGEMQNITTTRE--RVELRGMEKFTNYSVQVLAYTQA 1233
Query: 714 FEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
+G S+ QT +DVP GPP I+ + ++V + W PP NG+I Y + +
Sbjct: 1234 GDGVRSSVLYIQTKEDVP-GPPAGIKAVPSSASSVVVSWLPP--TKPNGVIRKYTIFCS- 1289
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+ + + T + + +L G Y + +AA T G G S+KV
Sbjct: 1290 -SPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKV 1340
Score = 141 bits (341), Expect = 2e-32
Identities = 135/524 (25%), Positives = 224/524 (42%), Gaps = 47/524 (8%)
Query: 9 GEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGL 66
G + Y + L VT + + C A GSPS A+RWY G + H + A G
Sbjct: 82 GTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGT 141
Query: 67 FFL-----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L A + +H + Y+C A N+ G RS N + AV RE + + E ++S +
Sbjct: 142 LQLYPFSPSAFNSFIHDND--YFCTAENAAGKIRSPNIRVK-AVFREPYTVRVEDQRSMR 198
Query: 122 GDTVVLECLPPRGSPE--PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRY 178
G+ V +CL P E V W+K+ +++ + R + G L I D ++ DA Y
Sbjct: 199 GNVAVFKCLIPSSVQEYVSVVSWEKDTVSII--PEHRFFITYHGGLYISDVQKEDALSTY 256
Query: 179 QCIARN--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
+CI ++ + TR+S A L + P ++ G G +V C G P+P
Sbjct: 257 RCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPA 316
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ W + G +P L + ++ D G Y CE N+ G+ A+G L V DP
Sbjct: 317 IRWLKD--GRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP 374
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
+ L+P + G+ +C TG PE T+ W N ++ P D+ +
Sbjct: 375 LHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRW--YRNTELVLP----DEAISIRGLSN 428
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
T+L I K+ S C A A ++ + + +D P I+++ P +
Sbjct: 429 ETLL-ITSAQKSHS-GAYQCFATRKAQTA---QDFAIIALEDGTPRIVSSFSEKVVNPGE 483
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQ--NHRRN--VTNDGTLV----LKDLDKSDSGT 464
++ C A P P + W + E +++ +HR N +DGT + + D G
Sbjct: 484 QFSLM-CAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGV 542
Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPT 508
Y C A + G + + V P P+I R +++++ G T
Sbjct: 543 YRCTARNLVGSAEYQARINVRGP--PSIRAMR--NITAVAGRDT 582
Score = 132 bits (319), Expect = 7e-30
Identities = 207/850 (24%), Positives = 335/850 (39%), Gaps = 109/850 (12%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRS---ILPAGGLF 67
P I+ + V + +L C A G+P P + W +V D +HR+ + G
Sbjct: 468 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 527
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G D GVY C A N G+A + A ++V R A DT++
Sbjct: 528 SHMNVTGPQIRDGGVYRCTARNLVGSAEYQ-ARINVRG-PPSIRAMRNITAVAGRDTLI- 584
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IARN 184
C G P ++ W K+ LL + R + + G L + D ++ D G Y C + +
Sbjct: 585 NCRVI-GYPYYSIKWYKDA--LLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQP 641
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA---- 239
+S +K+ P LI E A G + C V +P + WR+
Sbjct: 642 QLSISQSVHVAVKV---PPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVII 698
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
G + + + + SL++ +V L G Y+C A N+ VS L V PP + P
Sbjct: 699 SGSGVTIESKEFMS--SLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQP 756
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
N+ + G C+ G P P + W +G+ + +YH + + +L
Sbjct: 757 NNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSG-------NPQQYHPVPLTGRIQILPN 809
Query: 359 NDT----DKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKS 413
+ + +C A N G+ + LTV + P +IT+ P N T+ IK
Sbjct: 810 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTV-----KIPAMITSHP-NTTIAIKG 863
Query: 414 MA-VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTND------GTLVLKDLDKSDS 462
A CTA PII + +G+ +I R T D TL LK D+ DS
Sbjct: 864 HAKELNCTA-RGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDS 922
Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522
++C A + +G+ L V P P PP I V S+ L
Sbjct: 923 VFFSCHAINSYGEDRGLIQLTVQEP----------------PDPPELEI-REVKARSMNL 965
Query: 523 SWSQNNKIGSSSILGYQVEVFSR-ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
W+Q G+S I G+ +E ++ ++ + RN I+ ++Q + V L P
Sbjct: 966 RWTQRFD-GNSIITGFDIEYKNKSDSWDFKQSTRN------ISPTINQANIV--DLHPAS 1016
Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEA 641
Y + + N G S P S +T+ STE D +
Sbjct: 1017 VYSIRMYSFNKIGRSEP---SKELTI---------------STE---EAAPDGPPMDVTL 1055
Query: 642 TPIDSKTIKLMWEI----LNFYYLEGLFIYFRP-LDNITIEYEMKTILHSNDVSGFEITS 696
P+ S++I++ W+ L + G I +R +Y + + + D + + +
Sbjct: 1056 QPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDN 1115
Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
L+K+ +Y + F + G S+ A TL+DVP PP N+ + + + WS P
Sbjct: 1116 LKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPP 1175
Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
NG++ GY V+ L V + TT + L + +YSVQ+ A T
Sbjct: 1176 RSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVEL--RGMEKFTNYSVQVLAYTQA 1233
Query: 817 GLGPFSQKVY 826
G G S +Y
Sbjct: 1234 GDGVRSSVLY 1243
Score = 118 bits (285), Expect = 1e-25
Identities = 156/610 (25%), Positives = 242/610 (39%), Gaps = 41/610 (6%)
Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG--TARSRNAT 100
+ W K V ++ + I GGL+ + + Y C + Y T +S A
Sbjct: 219 VSWEKDTVSIIPEHRFFITYHGGLYI---SDVQKEDALSTYRCITKHKYSGETRQSNGAR 275
Query: 101 LHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
L V E + S + G TV L C G P P + W K+G+ L DSR
Sbjct: 276 LSVTDPAESIPTILDGFHSQEVWAGHTVELPCTAS-GYPIPAIRWLKDGRPL--PADSRW 332
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT-GPEDVVAQTG 216
G L I D R D+G Y C N G+ E A L + I P +T P+ + G
Sbjct: 333 TKRITG-LTISDLRTEDSGTYICEVTNTFGSAE-ATGILMV-IDPLHVTLTPKKLKTGIG 389
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVILADEGEYSCEA 274
S+V C + G P + W R+ +P + + L + +L + + + G Y C A
Sbjct: 390 STVILSCALTGSPEFTIRWYRNTELV-LPDEAISIRGLSNETLLITSAQKSHSGAYQCFA 448
Query: 275 ENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
+ + D P I S + V G C A G P PT+ W+++ +
Sbjct: 449 TRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALD-DEP 507
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSD 392
I+ G R + + DG T+ +N T + C+A N GS+ + ++ V
Sbjct: 508 IVRDGSHRTNQYTMS--DGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV--- 562
Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
R PP I N T + C I P I WY + L NHR+ V +GTL
Sbjct: 563 --RGPPSI-RAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTL 619
Query: 453 VLKDLDKS-DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI 511
L D+ K D G Y C + + S ++ V + P I F +S+ P
Sbjct: 620 KLTDVQKGMDEGEYLCSVLIQPQLSI-SQSVHVAVKVPPLIQPFEFPP-ASIGQLLYIPC 677
Query: 512 THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS----GNNTPRNSRGWVVIARRV 567
+ D + ++W K G I G V + S+E +S + + +++ + IA
Sbjct: 678 VVSSGDMPIRITW---RKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNA 734
Query: 568 HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD-SVTVGDDSNSLWE-GTGVSNSTE 625
T + LI + F+V+ N G+ G + V + SV +W+ G N +
Sbjct: 735 AATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 794
Query: 626 YRNNILTDHI 635
Y LT I
Sbjct: 795 YHPVPLTGRI 804
Score = 92.3 bits (219), Expect = 1e-17
Identities = 119/466 (25%), Positives = 189/466 (40%), Gaps = 47/466 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP IRWY+ LV+ D SI L + + HS G Y C AT
Sbjct: 394 LSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHS--GAYQCFATRK 451
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
TA+ A + + K G+ L C +G+P P V W + + ++
Sbjct: 452 AQTAQDF-AIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAA-KGAPPPTVTWALDDEPIV 509
Query: 151 FDGDSRMH---LVDG---GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-PY 203
DG R + + DG ++ + + D G Y+C ARN G+ E +I+++ P
Sbjct: 510 RDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQA---RINVRGPP 566
Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNV 262
I ++ A G CRV G P + W + A +P R V ++G+L+L +V
Sbjct: 567 SIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL--LLPDNHRQVVFENGTLKLTDV 624
Query: 263 ILA-DEGEYSCEAENSVG-AVSASGYLTVYDPPSIN---LSPNSVNVESGNVARFTCTAT 317
DEGEY C ++S S ++ V PP I P S+ G + C +
Sbjct: 625 QKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASI----GQLLYIPCVVS 680
Query: 318 GRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
P W +G I G++ + + ++ L I+ + N C A N
Sbjct: 681 SGDMPIRITWRKDGQVIISGSGVTIESK------EFMSSLQISSVSLKHNGN-YTCIASN 733
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEG 435
A + +L V R PP P+NQ V C+ P P + W + +G
Sbjct: 734 AAATVSRERQLIV-----RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKG 788
Query: 436 EALIQNH-------RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
Q + R + + +L+++ + + D G Y C AS+ G
Sbjct: 789 SGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 834
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/186 (23%), Positives = 79/186 (42%), Gaps = 8/186 (4%)
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
+++ T S ++ I L + Y + F K +PS T + PDGPP+
Sbjct: 992 DFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM 1051
Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
++ + + + ++ + W P+ +LQNG+I GY + + P + +I S +
Sbjct: 1052 DVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEV 1110
Query: 797 MT--NLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGD 854
T NL Y V + A G GP S ++ + + D+ S+ P N + D
Sbjct: 1111 YTLDNLKKFAQYGVVVQAFNRAGTGPSSSEI-----NATTLEDVPSQPPENVRALSITSD 1165
Query: 855 FVMETW 860
+ +W
Sbjct: 1166 VAVISW 1171
Score = 51.6 bits (118), Expect = 2e-05
Identities = 63/241 (26%), Positives = 102/241 (42%), Gaps = 35/241 (14%)
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
+AV AG K+T+ P II+ G + T +K + + PC ++ P P + W
Sbjct: 1326 AAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRL-PCNSVGDPAPAVKWT 1384
Query: 433 FEGE-----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ E + HR TN GTL+L+ + DSG YTC A++ G LLV P
Sbjct: 1385 KDSEDSAIPVSMDGHRLIHTN-GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP 1443
Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
P P ++ + +S+TL+W + G SSI G+ ++ +S +
Sbjct: 1444 ----------------PDQPRLTVS-KTSASSITLTWIPGDN-GGSSIRGFVLQ-YSVD- 1483
Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
NS W + + + + SL G Y + +NS G S + ++ T
Sbjct: 1484 --------NSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTH 1535
Query: 608 G 608
G
Sbjct: 1536 G 1536
Score = 43.2 bits (97), Expect = 0.006
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
Query: 8 SGEAPY-IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK----GGVLVVSDTHRSILP 62
+G+AP II VT + L C + G P+PA++W K + V D HR ++
Sbjct: 1345 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHR-LIH 1403
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G LRA D+G Y C ATN+ G
Sbjct: 1404 TNGTLLLRAVKA---EDSGYYTCTATNTGG 1430
Score = 38.7 bits (86), Expect = 0.13
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
V C GDP P V W + + +P+ G + +G+L L V D G Y+C A
Sbjct: 1367 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1426
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G + L V PP
Sbjct: 1427 NTGGFDTIIVNLLVQVPP 1444
Score = 37.5 bits (83), Expect = 0.29
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 10/99 (10%)
Query: 134 GSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G P P V W K+ + + DG +H G L+++ + D+G Y C A N G
Sbjct: 1375 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHT--NGTLLLRAVKAEDSGYYTCTATNTGGF- 1431
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
++ I L + + P P V++T +S + GD
Sbjct: 1432 DTIIVNLLVQVPP---DQPRLTVSKTSASSITLTWIPGD 1467
>AF334384-1|AAL57166.1| 2053|Homo sapiens Down syndrome cell adhesion
molecule DSCAML1 protein.
Length = 2053
Score = 164 bits (399), Expect = 1e-39
Identities = 207/832 (24%), Positives = 340/832 (40%), Gaps = 74/832 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I ++T + +NCR G P +I+WYK +L+ D HR ++ G L+
Sbjct: 505 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGT--LKL 561
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
T + D G Y C + S++ +HVAV E ++ G + + C+
Sbjct: 562 TDVQKGMDEGEYLCSVLIQPQLSISQS--VHVAVKVPPLIQPFEFPPASIGQLLYIPCVV 619
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G + W+K+GQ ++ + + +L I G Y CIA NAA T
Sbjct: 620 SSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAAT-V 678
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN------M 244
S L + + P + P + G + C V G P P V+W+ + G GN +
Sbjct: 679 SRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPV 738
Query: 245 PL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302
PL GR+++L + SL + +V+ D G Y C+A N VG +S S +LTV P I PN+
Sbjct: 739 PLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTT 798
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG----VTVLTI 358
G+ CTA G + W E T+I P R +A A D V+ L +
Sbjct: 799 IAIKGHAKELNCTARGERPIIIRW--EKGDTVIDP--DRVMRYAIATKDNGDEVVSTLKL 854
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
D+ DS C A+N G +LTV D PP + +++ ++ F
Sbjct: 855 KPADRGDS-VFFSCHAINSYGEDRGLIQLTVQEPPD-PPELEIREVKARSMNLRWTQRFD 912
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+I T I + RN++ N +V DL + + + ++ G+
Sbjct: 913 GNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIV--DLHPASVYSIRMYSFNKIGR 970
Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSS 534
S L + + + ++ GPP VT S+ ++W K + +
Sbjct: 971 SEPSKELTI------------STEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGV 1018
Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
I GYQ+ RE G+N V + Y + +L Y +V+ N G
Sbjct: 1019 IRGYQIGY--RENSPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 1073
Query: 595 LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
+GPS + T +D S R +T + + + P S
Sbjct: 1074 -TGPSSSEINATTLEDVPS-------QPPENVRALSITSDVAVISWSEPPRS-------- 1117
Query: 655 ILNFYYLEGLFIYFRPLDNITIEY-EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKK 713
LN L+G + F L + E+ EM+ I + + E+ + K+T Y ++ + +
Sbjct: 1118 TLN-GVLKGYRVIFWSL-YVDGEWGEMQNITTTRE--RVELRGMEKFTNYSVQVLAYTQA 1173
Query: 714 FEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
+G S+ QT +DVP GPP I+ + ++V + W PP NG+I Y + +
Sbjct: 1174 GDGVRSSVLYIQTKEDVP-GPPAGIKAVPSSASSVVVSWLPP--TKPNGVIRKYTIFCS- 1229
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+ + + T + + +L G Y + +AA T G G S+KV
Sbjct: 1230 -SPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKV 1280
Score = 142 bits (343), Expect = 9e-33
Identities = 135/524 (25%), Positives = 225/524 (42%), Gaps = 47/524 (8%)
Query: 9 GEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGL 66
G + Y + L VT + + C A GSPS A+RWY G + H + A G
Sbjct: 22 GTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGT 81
Query: 67 FFL-----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L A + +H + Y+C A N+ G RS N + AV RE + + E ++S +
Sbjct: 82 LQLYPFSPSAFNSFIHDND--YFCTAENAAGKIRSPNIRVK-AVFREPYTVRVEDQRSMR 138
Query: 122 GDTVVLECLPPRGSPE--PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRY 178
G+ V +CL P E V W+K+ +++ ++R + G L I D ++ DA Y
Sbjct: 139 GNVAVFKCLIPSSVQEYVSVVSWEKDTVSII--PENRFFITYHGGLYISDVQKEDALSTY 196
Query: 179 QCIARN--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
+CI ++ + TR+S A L + P ++ G G +V C G P+P
Sbjct: 197 RCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPA 256
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ W + G +P L + ++ D G Y CE N+ G+ A+G L V DP
Sbjct: 257 IRWLKD--GRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP 314
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
+ L+P + G+ +C TG PE T+ W N ++ P D+ +
Sbjct: 315 LHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRW--YRNTELVLP----DEAISIRGLSN 368
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
T+L I K+ S C A A ++ + + +D P I+++ P +
Sbjct: 369 ETLL-ITSAQKSHS-GAYQCFATRKAQTA---QDFAIIALEDGTPRIVSSFSEKVVNPGE 423
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQ--NHRRN--VTNDGTLV----LKDLDKSDSGT 464
++ C A P P + W + E +++ +HR N +DGT + + D G
Sbjct: 424 QFSLM-CAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGV 482
Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPT 508
Y C A + G + + V P P+I R +++++ G T
Sbjct: 483 YRCTARNLVGSAEYQARINVRGP--PSIRAMR--NITAVAGRDT 522
Score = 132 bits (319), Expect = 7e-30
Identities = 207/850 (24%), Positives = 335/850 (39%), Gaps = 109/850 (12%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRS---ILPAGGLF 67
P I+ + V + +L C A G+P P + W +V D +HR+ + G
Sbjct: 408 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 467
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G D GVY C A N G+A + A ++V R A DT++
Sbjct: 468 SHMNVTGPQIRDGGVYRCTARNLVGSAEYQ-ARINVRG-PPSIRAMRNITAVAGRDTLI- 524
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IARN 184
C G P ++ W K+ LL + R + + G L + D ++ D G Y C + +
Sbjct: 525 NCRVI-GYPYYSIKWYKDA--LLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQP 581
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA---- 239
+S +K+ P LI E A G + C V +P + WR+
Sbjct: 582 QLSISQSVHVAVKV---PPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVII 638
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
G + + + + SL++ +V L G Y+C A N+ VS L V PP + P
Sbjct: 639 SGSGVTIESKEFMS--SLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQP 696
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
N+ + G C+ G P P + W +G+ + +YH + + +L
Sbjct: 697 NNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSG-------NPQQYHPVPLTGRIQILPN 749
Query: 359 NDT----DKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKS 413
+ + +C A N G+ + LTV + P +IT+ P N T+ IK
Sbjct: 750 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTV-----KIPAMITSHP-NTTIAIKG 803
Query: 414 MA-VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTND------GTLVLKDLDKSDS 462
A CTA PII + +G+ +I R T D TL LK D+ DS
Sbjct: 804 HAKELNCTA-RGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDS 862
Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522
++C A + +G+ L V P P PP I V S+ L
Sbjct: 863 VFFSCHAINSYGEDRGLIQLTVQEP----------------PDPPELEI-REVKARSMNL 905
Query: 523 SWSQNNKIGSSSILGYQVEVFSR-ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
W+Q G+S I G+ +E ++ ++ + RN I+ ++Q + V L P
Sbjct: 906 RWTQRFD-GNSIITGFDIEYKNKSDSWDFKQSTRN------ISPTINQANIV--DLHPAS 956
Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEA 641
Y + + N G S P S +T+ STE D +
Sbjct: 957 VYSIRMYSFNKIGRSEP---SKELTI---------------STE---EAAPDGPPMDVTL 995
Query: 642 TPIDSKTIKLMWEI----LNFYYLEGLFIYFRP-LDNITIEYEMKTILHSNDVSGFEITS 696
P+ S++I++ W+ L + G I +R +Y + + + D + + +
Sbjct: 996 QPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDN 1055
Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
L+K+ +Y + F + G S+ A TL+DVP PP N+ + + + WS P
Sbjct: 1056 LKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPP 1115
Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
NG++ GY V+ L V + TT + L + +YSVQ+ A T
Sbjct: 1116 RSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVEL--RGMEKFTNYSVQVLAYTQA 1173
Query: 817 GLGPFSQKVY 826
G G S +Y
Sbjct: 1174 GDGVRSSVLY 1183
Score = 119 bits (287), Expect = 6e-26
Identities = 156/610 (25%), Positives = 242/610 (39%), Gaps = 41/610 (6%)
Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG--TARSRNAT 100
+ W K V ++ + I GGL+ + + Y C + Y T +S A
Sbjct: 159 VSWEKDTVSIIPENRFFITYHGGLYI---SDVQKEDALSTYRCITKHKYSGETRQSNGAR 215
Query: 101 LHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
L V E + S + G TV L C G P P + W K+G+ L DSR
Sbjct: 216 LSVTDPAESIPTILDGFHSQEVWAGHTVELPCTAS-GYPIPAIRWLKDGRPL--PADSRW 272
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT-GPEDVVAQTG 216
G L I D R D+G Y C N G+ E A L + I P +T P+ + G
Sbjct: 273 TKRITG-LTISDLRTEDSGTYICEVTNTFGSAE-ATGILMV-IDPLHVTLTPKKLKTGIG 329
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVILADEGEYSCEA 274
S+V C + G P + W R+ +P + + L + +L + + + G Y C A
Sbjct: 330 STVILSCALTGSPEFTIRWYRNTELV-LPDEAISIRGLSNETLLITSAQKSHSGAYQCFA 388
Query: 275 ENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
+ + D P I S + V G C A G P PT+ W+++ +
Sbjct: 389 TRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALD-DEP 447
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSD 392
I+ G R + + DG T+ +N T + C+A N GS+ + ++ V
Sbjct: 448 IVRDGSHRTNQYTMS--DGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV--- 502
Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
R PP I N T + C I P I WY + L NHR+ V +GTL
Sbjct: 503 --RGPPSI-RAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTL 559
Query: 453 VLKDLDKS-DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI 511
L D+ K D G Y C + + S ++ V + P I F +S+ P
Sbjct: 560 KLTDVQKGMDEGEYLCSVLIQPQLSI-SQSVHVAVKVPPLIQPFEFPP-ASIGQLLYIPC 617
Query: 512 THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS----GNNTPRNSRGWVVIARRV 567
+ D + ++W K G I G V + S+E +S + + +++ + IA
Sbjct: 618 VVSSGDMPIRITW---RKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNA 674
Query: 568 HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD-SVTVGDDSNSLWE-GTGVSNSTE 625
T + LI + F+V+ N G+ G + V + SV +W+ G N +
Sbjct: 675 AATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 734
Query: 626 YRNNILTDHI 635
Y LT I
Sbjct: 735 YHPVPLTGRI 744
Score = 92.3 bits (219), Expect = 1e-17
Identities = 119/466 (25%), Positives = 189/466 (40%), Gaps = 47/466 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP IRWY+ LV+ D SI L + + HS G Y C AT
Sbjct: 334 LSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHS--GAYQCFATRK 391
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
TA+ A + + K G+ L C +G+P P V W + + ++
Sbjct: 392 AQTAQDF-AIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAA-KGAPPPTVTWALDDEPIV 449
Query: 151 FDGDSRMH---LVDG---GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-PY 203
DG R + + DG ++ + + D G Y+C ARN G+ E +I+++ P
Sbjct: 450 RDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQA---RINVRGPP 506
Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNV 262
I ++ A G CRV G P + W + A +P R V ++G+L+L +V
Sbjct: 507 SIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL--LLPDNHRQVVFENGTLKLTDV 564
Query: 263 ILA-DEGEYSCEAENSVG-AVSASGYLTVYDPPSIN---LSPNSVNVESGNVARFTCTAT 317
DEGEY C ++S S ++ V PP I P S+ G + C +
Sbjct: 565 QKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASI----GQLLYIPCVVS 620
Query: 318 GRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
P W +G I G++ + + ++ L I+ + N C A N
Sbjct: 621 SGDMPIRITWRKDGQVIISGSGVTIESK------EFMSSLQISSVSLKHNGN-YTCIASN 673
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEG 435
A + +L V R PP P+NQ V C+ P P + W + +G
Sbjct: 674 AAATVSRERQLIV-----RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKG 728
Query: 436 EALIQNH-------RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
Q + R + + +L+++ + + D G Y C AS+ G
Sbjct: 729 SGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 774
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/186 (23%), Positives = 79/186 (42%), Gaps = 8/186 (4%)
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
+++ T S ++ I L + Y + F K +PS T + PDGPP+
Sbjct: 932 DFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM 991
Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
++ + + + ++ + W P+ +LQNG+I GY + + P + +I S +
Sbjct: 992 DVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEV 1050
Query: 797 MT--NLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGD 854
T NL Y V + A G GP S ++ + + D+ S+ P N + D
Sbjct: 1051 YTLDNLKKFAQYGVVVQAFNRAGTGPSSSEI-----NATTLEDVPSQPPENVRALSITSD 1105
Query: 855 FVMETW 860
+ +W
Sbjct: 1106 VAVISW 1111
Score = 51.6 bits (118), Expect = 2e-05
Identities = 63/241 (26%), Positives = 102/241 (42%), Gaps = 35/241 (14%)
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
+AV AG K+T+ P II+ G + T +K + + PC ++ P P + W
Sbjct: 1266 AAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRL-PCNSVGDPAPAVKWT 1324
Query: 433 FEGE-----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ E + HR TN GTL+L+ + DSG YTC A++ G LLV P
Sbjct: 1325 KDSEDSAIPVSMDGHRLIHTN-GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP 1383
Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
P P ++ + +S+TL+W + G SSI G+ ++ +S +
Sbjct: 1384 ----------------PDQPRLTVS-KTSASSITLTWIPGDN-GGSSIRGFVLQ-YSVD- 1423
Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
NS W + + + + SL G Y + +NS G S + ++ T
Sbjct: 1424 --------NSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTH 1475
Query: 608 G 608
G
Sbjct: 1476 G 1476
Score = 43.2 bits (97), Expect = 0.006
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
Query: 8 SGEAPY-IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK----GGVLVVSDTHRSILP 62
+G+AP II VT + L C + G P+PA++W K + V D HR ++
Sbjct: 1285 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHR-LIH 1343
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G LRA D+G Y C ATN+ G
Sbjct: 1344 TNGTLLLRAVKA---EDSGYYTCTATNTGG 1370
Score = 38.7 bits (86), Expect = 0.13
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
V C GDP P V W + + +P+ G + +G+L L V D G Y+C A
Sbjct: 1307 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1366
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G + L V PP
Sbjct: 1367 NTGGFDTIIVNLLVQVPP 1384
Score = 37.5 bits (83), Expect = 0.29
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 10/99 (10%)
Query: 134 GSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G P P V W K+ + + DG +H G L+++ + D+G Y C A N G
Sbjct: 1315 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHT--NGTLLLRAVKAEDSGYYTCTATNTGGF- 1371
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
++ I L + + P P V++T +S + GD
Sbjct: 1372 DTIIVNLLVQVPP---DQPRLTVSKTSASSITLTWIPGD 1407
>AB032958-1|BAA86446.2| 2092|Homo sapiens KIAA1132 protein protein.
Length = 2092
Score = 164 bits (399), Expect = 1e-39
Identities = 207/832 (24%), Positives = 340/832 (40%), Gaps = 74/832 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I ++T + +NCR G P +I+WYK +L+ D HR ++ G L+
Sbjct: 544 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGT--LKL 600
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
T + D G Y C + S++ +HVAV E ++ G + + C+
Sbjct: 601 TDVQKGMDEGEYLCSVLIQPQLSISQS--VHVAVKVPPLIQPFEFPPASIGQLLYIPCVV 658
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G + W+K+GQ ++ + + +L I G Y CIA NAA T
Sbjct: 659 SSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAAT-V 717
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN------M 244
S L + + P + P + G + C V G P P V+W+ + G GN +
Sbjct: 718 SRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPV 777
Query: 245 PL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302
PL GR+++L + SL + +V+ D G Y C+A N VG +S S +LTV P I PN+
Sbjct: 778 PLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTT 837
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG----VTVLTI 358
G+ CTA G + W E T+I P R +A A D V+ L +
Sbjct: 838 IAIKGHAKELNCTARGERPIIIRW--EKGDTVIDP--DRVMRYAIATKDNGDEVVSTLKL 893
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
D+ DS C A+N G +LTV D PP + +++ ++ F
Sbjct: 894 KPADRGDS-VFFSCHAINSYGEDRGLIQLTVQEPPD-PPELEIREVKARSMNLRWTQRFD 951
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+I T I + RN++ N +V DL + + + ++ G+
Sbjct: 952 GNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIV--DLHPASVYSIRMYSFNKIGR 1009
Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSS 534
S L + + + ++ GPP VT S+ ++W K + +
Sbjct: 1010 SEPSKELTI------------STEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGV 1057
Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
I GYQ+ RE G+N V + Y + +L Y +V+ N G
Sbjct: 1058 IRGYQIGY--RENSPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 1112
Query: 595 LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
+GPS + T +D S R +T + + + P S
Sbjct: 1113 -TGPSSSEINATTLEDVPS-------QPPENVRALSITSDVAVISWSEPPRS-------- 1156
Query: 655 ILNFYYLEGLFIYFRPLDNITIEY-EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKK 713
LN L+G + F L + E+ EM+ I + + E+ + K+T Y ++ + +
Sbjct: 1157 TLN-GVLKGYRVIFWSL-YVDGEWGEMQNITTTRE--RVELRGMEKFTNYSVQVLAYTQA 1212
Query: 714 FEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
+G S+ QT +DVP GPP I+ + ++V + W PP NG+I Y + +
Sbjct: 1213 GDGVRSSVLYIQTKEDVP-GPPAGIKAVPSSASSVVVSWLPP--TKPNGVIRKYTIFCS- 1268
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+ + + T + + +L G Y + +AA T G G S+KV
Sbjct: 1269 -SPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKV 1319
Score = 142 bits (343), Expect = 9e-33
Identities = 135/524 (25%), Positives = 225/524 (42%), Gaps = 47/524 (8%)
Query: 9 GEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGL 66
G + Y + L VT + + C A GSPS A+RWY G + H + A G
Sbjct: 61 GTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGT 120
Query: 67 FFL-----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L A + +H + Y+C A N+ G RS N + AV RE + + E ++S +
Sbjct: 121 LQLYPFSPSAFNSFIHDND--YFCTAENAAGKIRSPNIRVK-AVFREPYTVRVEDQRSMR 177
Query: 122 GDTVVLECLPPRGSPE--PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRY 178
G+ V +CL P E V W+K+ +++ ++R + G L I D ++ DA Y
Sbjct: 178 GNVAVFKCLIPSSVQEYVSVVSWEKDTVSII--PENRFFITYHGGLYISDVQKEDALSTY 235
Query: 179 QCIARN--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
+CI ++ + TR+S A L + P ++ G G +V C G P+P
Sbjct: 236 RCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPA 295
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ W + G +P L + ++ D G Y CE N+ G+ A+G L V DP
Sbjct: 296 IRWLKD--GRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP 353
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
+ L+P + G+ +C TG PE T+ W N ++ P D+ +
Sbjct: 354 LHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRW--YRNTELVLP----DEAISIRGLSN 407
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
T+L I K+ S C A A ++ + + +D P I+++ P +
Sbjct: 408 ETLL-ITSAQKSHS-GAYQCFATRKAQTA---QDFAIIALEDGTPRIVSSFSEKVVNPGE 462
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQ--NHRRN--VTNDGTLV----LKDLDKSDSGT 464
++ C A P P + W + E +++ +HR N +DGT + + D G
Sbjct: 463 QFSLM-CAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGV 521
Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPT 508
Y C A + G + + V P P+I R +++++ G T
Sbjct: 522 YRCTARNLVGSAEYQARINVRGP--PSIRAMR--NITAVAGRDT 561
Score = 132 bits (319), Expect = 7e-30
Identities = 207/850 (24%), Positives = 335/850 (39%), Gaps = 109/850 (12%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRS---ILPAGGLF 67
P I+ + V + +L C A G+P P + W +V D +HR+ + G
Sbjct: 447 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 506
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G D GVY C A N G+A + A ++V R A DT++
Sbjct: 507 SHMNVTGPQIRDGGVYRCTARNLVGSAEYQ-ARINVRG-PPSIRAMRNITAVAGRDTLI- 563
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IARN 184
C G P ++ W K+ LL + R + + G L + D ++ D G Y C + +
Sbjct: 564 NCRVI-GYPYYSIKWYKDA--LLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQP 620
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA---- 239
+S +K+ P LI E A G + C V +P + WR+
Sbjct: 621 QLSISQSVHVAVKV---PPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVII 677
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
G + + + + SL++ +V L G Y+C A N+ VS L V PP + P
Sbjct: 678 SGSGVTIESKEFMS--SLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQP 735
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
N+ + G C+ G P P + W +G+ + +YH + + +L
Sbjct: 736 NNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSG-------NPQQYHPVPLTGRIQILPN 788
Query: 359 NDT----DKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKS 413
+ + +C A N G+ + LTV + P +IT+ P N T+ IK
Sbjct: 789 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTV-----KIPAMITSHP-NTTIAIKG 842
Query: 414 MA-VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTND------GTLVLKDLDKSDS 462
A CTA PII + +G+ +I R T D TL LK D+ DS
Sbjct: 843 HAKELNCTA-RGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDS 901
Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522
++C A + +G+ L V P P PP I V S+ L
Sbjct: 902 VFFSCHAINSYGEDRGLIQLTVQEP----------------PDPPELEI-REVKARSMNL 944
Query: 523 SWSQNNKIGSSSILGYQVEVFSR-ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
W+Q G+S I G+ +E ++ ++ + RN I+ ++Q + V L P
Sbjct: 945 RWTQRFD-GNSIITGFDIEYKNKSDSWDFKQSTRN------ISPTINQANIV--DLHPAS 995
Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEA 641
Y + + N G S P S +T+ STE D +
Sbjct: 996 VYSIRMYSFNKIGRSEP---SKELTI---------------STE---EAAPDGPPMDVTL 1034
Query: 642 TPIDSKTIKLMWEI----LNFYYLEGLFIYFRP-LDNITIEYEMKTILHSNDVSGFEITS 696
P+ S++I++ W+ L + G I +R +Y + + + D + + +
Sbjct: 1035 QPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDN 1094
Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
L+K+ +Y + F + G S+ A TL+DVP PP N+ + + + WS P
Sbjct: 1095 LKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPP 1154
Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
NG++ GY V+ L V + TT + L + +YSVQ+ A T
Sbjct: 1155 RSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVEL--RGMEKFTNYSVQVLAYTQA 1212
Query: 817 GLGPFSQKVY 826
G G S +Y
Sbjct: 1213 GDGVRSSVLY 1222
Score = 119 bits (287), Expect = 6e-26
Identities = 156/610 (25%), Positives = 242/610 (39%), Gaps = 41/610 (6%)
Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG--TARSRNAT 100
+ W K V ++ + I GGL+ + + Y C + Y T +S A
Sbjct: 198 VSWEKDTVSIIPENRFFITYHGGLYI---SDVQKEDALSTYRCITKHKYSGETRQSNGAR 254
Query: 101 LHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
L V E + S + G TV L C G P P + W K+G+ L DSR
Sbjct: 255 LSVTDPAESIPTILDGFHSQEVWAGHTVELPCTAS-GYPIPAIRWLKDGRPL--PADSRW 311
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT-GPEDVVAQTG 216
G L I D R D+G Y C N G+ E A L + I P +T P+ + G
Sbjct: 312 TKRITG-LTISDLRTEDSGTYICEVTNTFGSAE-ATGILMV-IDPLHVTLTPKKLKTGIG 368
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVILADEGEYSCEA 274
S+V C + G P + W R+ +P + + L + +L + + + G Y C A
Sbjct: 369 STVILSCALTGSPEFTIRWYRNTELV-LPDEAISIRGLSNETLLITSAQKSHSGAYQCFA 427
Query: 275 ENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
+ + D P I S + V G C A G P PT+ W+++ +
Sbjct: 428 TRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALD-DEP 486
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSD 392
I+ G R + + DG T+ +N T + C+A N GS+ + ++ V
Sbjct: 487 IVRDGSHRTNQYTMS--DGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV--- 541
Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
R PP I N T + C I P I WY + L NHR+ V +GTL
Sbjct: 542 --RGPPSI-RAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTL 598
Query: 453 VLKDLDKS-DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI 511
L D+ K D G Y C + + S ++ V + P I F +S+ P
Sbjct: 599 KLTDVQKGMDEGEYLCSVLIQPQLSI-SQSVHVAVKVPPLIQPFEFPP-ASIGQLLYIPC 656
Query: 512 THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS----GNNTPRNSRGWVVIARRV 567
+ D + ++W K G I G V + S+E +S + + +++ + IA
Sbjct: 657 VVSSGDMPIRITW---RKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNA 713
Query: 568 HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD-SVTVGDDSNSLWE-GTGVSNSTE 625
T + LI + F+V+ N G+ G + V + SV +W+ G N +
Sbjct: 714 AATVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQ 773
Query: 626 YRNNILTDHI 635
Y LT I
Sbjct: 774 YHPVPLTGRI 783
Score = 92.3 bits (219), Expect = 1e-17
Identities = 119/466 (25%), Positives = 189/466 (40%), Gaps = 47/466 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP IRWY+ LV+ D SI L + + HS G Y C AT
Sbjct: 373 LSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHS--GAYQCFATRK 430
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
TA+ A + + K G+ L C +G+P P V W + + ++
Sbjct: 431 AQTAQDF-AIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAA-KGAPPPTVTWALDDEPIV 488
Query: 151 FDGDSRMH---LVDG---GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-PY 203
DG R + + DG ++ + + D G Y+C ARN G+ E +I+++ P
Sbjct: 489 RDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQA---RINVRGPP 545
Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNV 262
I ++ A G CRV G P + W + A +P R V ++G+L+L +V
Sbjct: 546 SIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL--LLPDNHRQVVFENGTLKLTDV 603
Query: 263 ILA-DEGEYSCEAENSVG-AVSASGYLTVYDPPSIN---LSPNSVNVESGNVARFTCTAT 317
DEGEY C ++S S ++ V PP I P S+ G + C +
Sbjct: 604 QKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASI----GQLLYIPCVVS 659
Query: 318 GRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
P W +G I G++ + + ++ L I+ + N C A N
Sbjct: 660 SGDMPIRITWRKDGQVIISGSGVTIESK------EFMSSLQISSVSLKHNGN-YTCIASN 712
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEG 435
A + +L V R PP P+NQ V C+ P P + W + +G
Sbjct: 713 AAATVSRERQLIV-----RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKG 767
Query: 436 EALIQNH-------RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
Q + R + + +L+++ + + D G Y C AS+ G
Sbjct: 768 SGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 813
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/186 (23%), Positives = 79/186 (42%), Gaps = 8/186 (4%)
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
+++ T S ++ I L + Y + F K +PS T + PDGPP+
Sbjct: 971 DFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM 1030
Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
++ + + + ++ + W P+ +LQNG+I GY + + P + +I S +
Sbjct: 1031 DVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEV 1089
Query: 797 MT--NLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGD 854
T NL Y V + A G GP S ++ + + D+ S+ P N + D
Sbjct: 1090 YTLDNLKKFAQYGVVVQAFNRAGTGPSSSEI-----NATTLEDVPSQPPENVRALSITSD 1144
Query: 855 FVMETW 860
+ +W
Sbjct: 1145 VAVISW 1150
Score = 51.6 bits (118), Expect = 2e-05
Identities = 63/241 (26%), Positives = 102/241 (42%), Gaps = 35/241 (14%)
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
+AV AG K+T+ P II+ G + T +K + + PC ++ P P + W
Sbjct: 1305 AAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRL-PCNSVGDPAPAVKWT 1363
Query: 433 FEGE-----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ E + HR TN GTL+L+ + DSG YTC A++ G LLV P
Sbjct: 1364 KDSEDSAIPVSMDGHRLIHTN-GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP 1422
Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
P P ++ + +S+TL+W + G SSI G+ ++ +S +
Sbjct: 1423 ----------------PDQPRLTVS-KTSASSITLTWIPGDN-GGSSIRGFVLQ-YSVD- 1462
Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
NS W + + + + SL G Y + +NS G S + ++ T
Sbjct: 1463 --------NSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTH 1514
Query: 608 G 608
G
Sbjct: 1515 G 1515
Score = 43.2 bits (97), Expect = 0.006
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
Query: 8 SGEAPY-IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK----GGVLVVSDTHRSILP 62
+G+AP II VT + L C + G P+PA++W K + V D HR ++
Sbjct: 1324 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHR-LIH 1382
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G LRA D+G Y C ATN+ G
Sbjct: 1383 TNGTLLLRAVKA---EDSGYYTCTATNTGG 1409
Score = 38.7 bits (86), Expect = 0.13
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
V C GDP P V W + + +P+ G + +G+L L V D G Y+C A
Sbjct: 1346 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1405
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G + L V PP
Sbjct: 1406 NTGGFDTIIVNLLVQVPP 1423
Score = 37.5 bits (83), Expect = 0.29
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 10/99 (10%)
Query: 134 GSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G P P V W K+ + + DG +H G L+++ + D+G Y C A N G
Sbjct: 1354 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHT--NGTLLLRAVKAEDSGYYTCTATNTGGF- 1410
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
++ I L + + P P V++T +S + GD
Sbjct: 1411 DTIIVNLLVQVPP---DQPRLTVSKTSASSITLTWIPGD 1446
>AL834139-1|CAD38854.1| 1340|Homo sapiens hypothetical protein
protein.
Length = 1340
Score = 163 bits (395), Expect = 5e-39
Identities = 136/483 (28%), Positives = 200/483 (41%), Gaps = 31/483 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T +P + P V + L C A G P P I W K G+ V + +LP G
Sbjct: 838 FLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG 897
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R H DAG Y C A NS G+A + T V + + +G
Sbjct: 898 QL---RIAHASPE-DAGNYLCIAKNSAGSAMGK--TRLVVQVPPVIENGLPDLSTTEGSH 951
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
L C RGSPEPN+ W K+GQ + + + + G L++++ DAG Y C A N
Sbjct: 952 AFLPC-KARGSPEPNITWDKDGQPVS-GAEGKFTIQPSGELLVKNLEGQDAGTYTCTAEN 1009
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
A G + L I + P T P D + G + +C G P P + W + +
Sbjct: 1010 AVGRARRRVH-LTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVN----DR 1064
Query: 245 PLGRVKVLDDGSLRLDNVILA--DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
P+ DG L ++ D G Y C AEN VG A ++ V + P + S
Sbjct: 1065 PVTEGVSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQGEAFSY 1124
Query: 303 NVES-GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
VE G + C G P P + W +G P R + + +G LTI+ T
Sbjct: 1125 LVEPVGGSIQLDCVVRGDPVPDIHWIKDG-----LP--LRGSHLRHQLQNGS--LTIHRT 1175
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
+++D+ C A N G V K+ + P + P + T+ C A
Sbjct: 1176 ERDDA-GRYQCLAENEMG---VAKKVVILVLQSAP--VFQVEPQDMTVRSGDDVALRCQA 1229
Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P I W G+ L + R DG+L L++++ D+GTY CVA + G
Sbjct: 1230 TGEPTPTIEWLQAGQPLRASRRLRTLPDGSLWLENVETGDAGTYDCVAHNLLGSATARAF 1289
Query: 482 LLV 484
L+V
Sbjct: 1290 LVV 1292
Score = 162 bits (394), Expect = 6e-39
Identities = 130/470 (27%), Positives = 196/470 (41%), Gaps = 26/470 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAG 64
VT P I + D TV P L C + G P+P + W K G L + + P+G
Sbjct: 748 VTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSG 807
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L +A +H AG Y C A NS G A ++ L V L P ++ +
Sbjct: 808 ALEIGQALP--IH--AGRYTCSARNSAGVAH-KHVFLTVQASPVVKPL-PSVVRAVAEEE 861
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V+L C G P P + W+K G + +++ + GG L I A DAG Y CIA+N
Sbjct: 862 VLLPC-EASGIPRPTITWQKEGLNVATGVSTQV--LPGGQLRIAHASPEDAGNYLCIAKN 918
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
+AG+ L + + P + G D+ GS C+ G P P++ W + +
Sbjct: 919 SAGSAMGK-TRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSG 977
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
G+ + G L + N+ D G Y+C AEN+VG +LT+ P P ++
Sbjct: 978 AEGKFTIQPSGELLVKNLEGQDAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSL 1037
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G+ C A G P P + W+V N + G+S DG + L +
Sbjct: 1038 RLGDRLWLRCAARGSPTPRIGWTV--NDRPVTEGVSEQ--------DGGSTLQRAAVSRE 1087
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
DS T VC A N G + + V P + S P+ C
Sbjct: 1088 DS-GTYVCWAENRVGRTQAVSFVHV----KEAPVLQGEAFSYLVEPVGGSIQLDCVVRGD 1142
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P I W +G L +H R+ +G+L + ++ D+G Y C+A + G
Sbjct: 1143 PVPDIHWIKDGLPLRGSHLRHQLQNGSLTIHRTERDDAGRYQCLAENEMG 1192
Score = 140 bits (340), Expect = 2e-32
Identities = 130/452 (28%), Positives = 183/452 (40%), Gaps = 32/452 (7%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLV---VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
A L C A GSP P + W+K G + + +LP+ L L G D+ + C
Sbjct: 678 ALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNAL--LLTAPG--PQDSAQFEC 733
Query: 86 EATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
+N G A R T+HV + + + A VVL C G P P V W K
Sbjct: 734 VVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMA---PVVLTC-HSTGIPAPTVSWSK 789
Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
G L G S + G L I A AGRY C ARN+AG + L + P +
Sbjct: 790 AGAQLGARG-SGYRVSPSGALEIGQALPIHAGRYTCSARNSAGVAHKHV-FLTVQASPVV 847
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVI 263
P V A V C G P P + W++ G N+ G +VL G LR+ +
Sbjct: 848 KPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKE--GLNVATGVSTQVLPGGQLRIAHAS 905
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
D G Y C A+NS G+ L V PP I ++ G+ A C A G PEP
Sbjct: 906 PEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLSTTEGSHAFLPCKARGSPEPN 965
Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
+ W +G +S + T G L + + + D+ T C+A N G +
Sbjct: 966 ITWDKDGQ------PVSGAEGKFTIQPSG--ELLVKNLEGQDA-GTYTCTAENAVGRARR 1016
Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR 443
R LT+ P+ T P +++L + C A +P P I W + +
Sbjct: 1017 RVHLTIL-----VLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVS 1071
Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
TL + + DSGTY C A +R G+
Sbjct: 1072 EQ-DGGSTLQRAAVSREDSGTYVCWAENRVGR 1102
Score = 131 bits (316), Expect = 2e-29
Identities = 136/492 (27%), Positives = 209/492 (42%), Gaps = 36/492 (7%)
Query: 10 EAPYIIEQPLDVTVAR--HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
+ P E P TV++ P L C G P+P + W K + V S ++ GG
Sbjct: 34 QVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRL 93
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
L + AG Y C A N+ AR + R +G V L
Sbjct: 94 QLSRLQP---AQAGTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRL 150
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFD-GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+C G P P+V W K+G L D G +DGG+LV++ +DAG Y C+A N A
Sbjct: 151 DC-EADGQPPPDVAWLKDGSPLGQDMGPHLRFYLDGGSLVLKGLWASDAGAYTCVAHNPA 209
Query: 187 GTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
G ++ + T+ + + P + G + +V++ G VT C V G P V W + G
Sbjct: 210 G-EDARLHTVNVLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKD--GLP 266
Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
+PL + +L +LR+ V LAD G ++C A + G A T+ P ++ S S
Sbjct: 267 LPLSQRTLLHGSGHTLRISKVQLADAGIFTCVAASPAGV--ADRNFTLQCP--LSWSRWS 322
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ + RP S G + + + ++ G + L +
Sbjct: 323 SRMTWWWFVAPWWNSRARPGAFPCLSCRGMK-------DGEPLLSQSLEQGPS-LQLEAV 374
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCT 420
DS T C AV+ AG + +LTV PP I +G P+ +L + C
Sbjct: 375 GAGDS-GTYSCVAVSEAGEARRHFQLTVM----EPPHIEDSGQPTELSLTPGAPMELLCD 429
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
A TP+P I W+ +G+AL + N L ++++ D+G YTC+A S G S
Sbjct: 430 AQGTPQPNITWHKDGQALTR-LENNSRATRVLRVENVQVRDAGLYTCLAESPAGAIEKSF 488
Query: 481 ALLVDSPINPNI 492
+ V +P PNI
Sbjct: 489 RVRVQAP--PNI 498
Score = 122 bits (294), Expect = 8e-27
Identities = 123/475 (25%), Positives = 190/475 (40%), Gaps = 48/475 (10%)
Query: 6 VTSGEAPYIIE--QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
+T E P+I + QP ++++ P L C A G+P P I W+K G + + S
Sbjct: 399 LTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTRLENNSRATR 458
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG- 122
LR + +V DAG+Y C A + G + V V + P + G
Sbjct: 459 ----VLRVENVQVR-DAGLYTCLAESPAGAIEK---SFRVRVQAPPNIVGPRGPRFVVGL 510
Query: 123 --DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+VLEC P P + W ++G L D ++ G L +Q D+G Y C
Sbjct: 511 APGQLVLEC-SVEAEPAPKITWHRDGIVLQEDAHTQFP-ERGRFLQLQALSTADSGDYSC 568
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
ARNAAG+ A ++IH P + +GP V + C+ G P P V WR+
Sbjct: 569 TARNAAGSTSVAFR-VEIHTVPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDRV 627
Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
+ R ++L +GSLR+ V+ D G Y C A NS G+ L V
Sbjct: 628 PLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRV----------- 676
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
+A C A+G P+P + W +G + + + Y L +
Sbjct: 677 --------LALLPCEASGSPKPLVVWWKDGQKLDF--RLQQGAYRLLP----SNALLLTA 722
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
DS C N G + ++TV PP I + ++ T+ + + V C
Sbjct: 723 PGPQDSAQ-FECVVSNEVGEAHRLYQVTV-----HVPPTIADDQTDFTVTMMAPVVLTCH 776
Query: 421 AICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+ P P ++W G L + V+ G L + +G YTC A + G
Sbjct: 777 STGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSAG 831
Score = 119 bits (287), Expect = 6e-26
Identities = 118/460 (25%), Positives = 175/460 (38%), Gaps = 45/460 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C P+P I W++ G+++ D H G L+A +D+G Y C A N+
Sbjct: 517 LECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALST---ADSGDYSCTARNA 573
Query: 91 YG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
G T+ + +H R P + + T +L C G P P V W+K+ +
Sbjct: 574 AGSTSVAFRVEIHTV---PTIRSGPPAVNVSVNQTALLPCQAD-GVPAPLVSWRKD-RVP 628
Query: 150 LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
L R ++ G+L IQ DAG Y C+A N+AG+ + + P
Sbjct: 629 LDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLALLP------- 681
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL--GRVKVLDDGSLRLDNVILADE 267
C G P P V+W + + L G ++L +L L D
Sbjct: 682 -------------CEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDS 728
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
++ C N VG +TV+ PP+I V TC +TG P PT+ WS
Sbjct: 729 AQFECVVSNEVGEAHRLYQVTVHVPPTIADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWS 788
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
G + G Y + G + + R T CSA N AG + L
Sbjct: 789 KAGAQL----GARGSGYRVSP--SGALEIG-QALPIHAGRYT--CSARNSAGVAHKHVFL 839
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
TV + P++ PS + + PC A P P I W EG + V
Sbjct: 840 TVQAS-----PVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVL 894
Query: 448 NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
G L + D+G Y C+A + G + L+V P
Sbjct: 895 PGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVP 934
Score = 110 bits (264), Expect = 3e-23
Identities = 73/252 (28%), Positives = 115/252 (45%), Gaps = 11/252 (4%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
D+G Y C A + G AR + E +P G + L C +G+P+P
Sbjct: 378 DSGTYSCVAVSEAGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLC-DAQGTPQP 436
Query: 139 NVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
N+ W K+GQ L + +SR V L +++ + DAG Y C+A + AG E + ++
Sbjct: 437 NITWHKDGQALTRLENNSRATRV----LRVENVQVRDAGLYTCLAESPAGAIEKSFR-VR 491
Query: 198 IHIKPYLI--TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
+ P ++ GP VV + +C V +P P + W R G + + G
Sbjct: 492 VQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRD-GIVLQEDAHTQFPERG 550
Query: 256 S-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
L+L + AD G+YSC A N+ G+ S + + ++ P+I P +VNV A C
Sbjct: 551 RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPC 610
Query: 315 TATGRPEPTMFW 326
A G P P + W
Sbjct: 611 QADGVPAPLVSW 622
Score = 102 bits (244), Expect = 9e-21
Identities = 114/460 (24%), Positives = 200/460 (43%), Gaps = 53/460 (11%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
T+ C GSP + W K G L + + R++L G LR + ++ +DAG++ C A +
Sbjct: 245 TMVCPVRGSPPIHVSWLKDG-LPLPLSQRTLLHGSG-HTLRISKVQL-ADAGIFTCVAAS 301
Query: 90 SYGTARSRNATLHVAVL--REEFRLE----PESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
G A RN TL + R R+ +++ CL RG
Sbjct: 302 PAGVA-DRNFTLQCPLSWSRWSSRMTWWWFVAPWWNSRARPGAFPCLSCRGM-------- 352
Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
K+G+ LL L G +L ++ D+G Y C+A + AG L + P+
Sbjct: 353 KDGEPLLSQS-----LEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQ-LTVMEPPH 406
Query: 204 LITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRL 259
+ P ++ G+ + C G P P++ W + L R++ + LR+
Sbjct: 407 IEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDG----QALTRLENNSRATRVLRV 462
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS----VNVESGNVARFTCT 315
+NV + D G Y+C AE+ GA+ S + V PP+I + P V + G + C+
Sbjct: 463 ENVQVRDAGLYTCLAESPAGAIEKSFRVRVQAPPNI-VGPRGPRFVVGLAPGQLV-LECS 520
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
P P + W +G I+ + ++ F + + ++ D D C+A
Sbjct: 521 VEAEPAPKITWHRDG---IVLQEDAHTQFPERGRF--LQLQALSTADSGDYS----CTAR 571
Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG 435
N AGS+ V ++ + + P I +GP + + A+ PC A P P+++W +
Sbjct: 572 NAAGSTSVAFRVEIHT-----VPTIRSGPPAVNVSVNQTALLPCQADGVPAPLVSWRKDR 626
Query: 436 EAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
L ++ R + +G+L ++ + D+G Y C+AS+ G
Sbjct: 627 VPLDPRSPRFEILPEGSLRIQPVLAQDAGHYLCLASNSAG 666
Score = 85.0 bits (201), Expect = 1e-15
Identities = 84/316 (26%), Positives = 123/316 (38%), Gaps = 18/316 (5%)
Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQC 223
L IQ+A+ +D G Y C N AG TL + + P + V+Q GS + C
Sbjct: 1 LEIQEAQVSDKGLYSCKVSNVAGEAVRTF-TLTVQVPPTFENPKTETVSQVAGSPLVLTC 59
Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSA 283
V G P P V W + V G L+L + A G Y+C AEN+
Sbjct: 60 DVSGVPAPTVTWLKDRMPVESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARK 119
Query: 284 SGYLTVYDPPSINLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
+ V P I S +V G R C A G+P P + W +G+ G
Sbjct: 120 DFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPL----GQDM 175
Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
H DG + L + +D+ C A N AG + V PP I
Sbjct: 176 GP-HLRFYLDGGS-LVLKGLWASDA-GAYTCVAHNPAGEDARLHTVNVLV----PPTIKQ 228
Query: 402 NGPSNQTLPIK--SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLD 458
+ TL + + C +P ++W +G L + R + G TL + +
Sbjct: 229 GADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQ 288
Query: 459 KSDSGTYTCVASSRHG 474
+D+G +TCVA+S G
Sbjct: 289 LADAGIFTCVAASPAG 304
Score = 84.2 bits (199), Expect = 3e-15
Identities = 74/263 (28%), Positives = 106/263 (40%), Gaps = 17/263 (6%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
SD G+Y C+ +N G A R TL V V + E+ G +VL C G P
Sbjct: 9 SDKGLYSCKVSNVAGEA-VRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTC-DVSGVPA 66
Query: 138 PNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQCIARN--AAGTRESAI 193
P V W K+ + S +H V GG L + + AG Y C+A N A ++ +
Sbjct: 67 PTVTWLKDRMPV---ESSAVHGVVSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVV 123
Query: 194 ATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV 251
A L I+ + V+ G V C G P PDV W + +G ++
Sbjct: 124 AVLVAPRIRSSGVAREHHVLE--GQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRF 181
Query: 252 -LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV---ESG 307
LD GSL L + +D G Y+C A N G + + V PP+I + G
Sbjct: 182 YLDGGSLVLKGLWASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGADGSGTLVSRPG 241
Query: 308 NVARFTCTATGRPEPTMFWSVEG 330
+ C G P + W +G
Sbjct: 242 ELVTMVCPVRGSPPIHVSWLKDG 264
Score = 41.1 bits (92), Expect = 0.023
Identities = 34/141 (24%), Positives = 60/141 (42%), Gaps = 6/141 (4%)
Query: 403 GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL---IQNHRRNVTNDGTLVLKDLDK 459
G Q ++ +A+ PC A +P+P++ W+ +G+ L +Q + L+L
Sbjct: 666 GSDRQGRDLRVLALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGP 725
Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519
DS + CV S+ G+ + V P P I + D + P H+ +
Sbjct: 726 QDSAQFECVVSNEVGEAHRLYQVTVHVP--PTIADDQ-TDFTVTMMAPVVLTCHSTGIPA 782
Query: 520 VTLSWSQNNKIGSSSILGYQV 540
T+SWS+ + GY+V
Sbjct: 783 PTVSWSKAGAQLGARGSGYRV 803
>BC113118-1|AAI13119.1| 1028|Homo sapiens contactin 6 protein.
Length = 1028
Score = 162 bits (394), Expect = 6e-39
Identities = 137/490 (27%), Positives = 211/490 (43%), Gaps = 38/490 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+ P+ + PLD++ + LNC A G PSP RW + G + GG +
Sbjct: 30 QEPHDVIFPLDLSKSE---VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAI 86
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLE 128
+ H D G+Y C ATN GT SR A L A + E+F + S S +G VVL
Sbjct: 87 NSPH--TDQDIGMYQCLATNLLGTILSRKAKLQFAYI-EDFETKTRSTVSVREGQGVVLL 143
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187
C PP + + W N L D+R + + GNL I +D G Y C N
Sbjct: 144 CGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEA 203
Query: 188 TRESAIATLKI---------HIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
R + +P + + PE + A SSV +C G+P+PD+ WRR
Sbjct: 204 QRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRR 263
Query: 238 SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
G +P G+VK + L + N DEG Y C A N G A G L Y PP
Sbjct: 264 -LDGSPLP-GKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWE 321
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
+ ++ + + C A+G+P P W G R + P + T + +T+L
Sbjct: 322 QKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGER--LNPEERIQIENGTLI---ITML 376
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT--LPIKSM 414
++D+ C+A N + +L V + P + P + + +
Sbjct: 377 NVSDS------GVYQCAAENKYQIIYANAELRVLAS----APDFSKSPVKKKSFVQVGGD 426
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
V C P I+W E L Q+ R + DG+L + ++ +SD+G+YTC+A+++ G
Sbjct: 427 IVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFG 486
Query: 475 KYVWSGALLV 484
+G+L+V
Sbjct: 487 TAKNTGSLIV 496
Score = 106 bits (254), Expect = 6e-22
Identities = 164/729 (22%), Positives = 279/729 (38%), Gaps = 85/729 (11%)
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
PE+ Q+A+ +V LEC G+P P++ W++ +G L G + + L I + +Q
Sbjct: 234 PETIQAAKDSSVKLECFA-LGNPVPDISWRRLDGSPL--PGKVK-YSKSQAILEIPNFQQ 289
Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
D G Y+CIA N G R A L + P ++ ++ ++C+ G P P
Sbjct: 290 EDEGFYECIASNLRG-RNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPW 348
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-D 291
W ++ N P R+++ ++G+L + + ++D G Y C AEN + A+ L V
Sbjct: 349 YTWLKNGERLN-PEERIQI-ENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLAS 406
Query: 292 PPSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P + SP V+ G C P + W G T+ R +
Sbjct: 407 APDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWK-RGTETL------RQSKRIFLL 459
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
DG L I + ++D+ + C A N G++ G L V + +IT PS +
Sbjct: 460 EDGS--LKIYNITRSDA-GSYTCIATNQFGTAKNTGSLIV-----KERTVITVPPSKMDV 511
Query: 410 PIKSMAVFPCTAICTP--EPIIAWYFEGEALIQN----HRRNVTND--GTLVLKDLDKSD 461
+ V PC P E + W+F G+ + H + + G L+++++
Sbjct: 512 TVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHH 571
Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT 521
SG Y C + ++V P PGPP +++ T+
Sbjct: 572 SGKYLCTVQTTLESLSAVADIIVRGP----------------PGPPEDVQVEDISSTTSQ 615
Query: 522 LSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
LSW S +++F+ +T TP S GW +A V ++ G
Sbjct: 616 LSWRAGPDNNSP------IQIFTIQT----RTPF-SVGWQAVA--------TVPEILNGK 656
Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVEL-IE 640
TY V GLS V G NS+ G S R + + I
Sbjct: 657 TYNATVV-----GLSPWVEYEFRVVAG---NSIGIGEPSEPSELLRTKASVPVVAPVNIH 708
Query: 641 ATPIDSKTIKLMWEILNFYYLEG----LFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696
+ + WE + G I FRP+ + T E + + S+ + S
Sbjct: 709 GGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFV-YRNES 767
Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
+ + +E + + + EG S + + +D P P + + + + + W+
Sbjct: 768 IIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIA 827
Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
G + GY V+ W D + +SM+ T+ +T L + Y + A
Sbjct: 828 WNRNTGRVLGYEVLY-WTD-DSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTA 885
Query: 817 GLGPFSQKV 825
G GP S V
Sbjct: 886 GTGPSSPPV 894
Score = 99 bits (238), Expect = 5e-20
Identities = 80/282 (28%), Positives = 124/282 (43%), Gaps = 22/282 (7%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C+A G P+P W K G + + R + G L SD+GVY C A N Y
Sbjct: 339 CKASGKPNPWYTWLKNGERL-NPEERIQIENGTLIITMLNV----SDSGVYQCAAENKYQ 393
Query: 93 TARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
+ NA L V +F P K+S G +V+ C P P + WK+ +TL
Sbjct: 394 IIYA-NAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGC-KPNAFPRAAISWKRGTETLR 451
Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
R+ L++ G+L I + ++DAG Y CIA N GT ++ +L + + + P
Sbjct: 452 --QSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNT-GSLIVKERTVITVPPSK 508
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-------RVKVLDDGSLRLDNVI 263
+ G S+ C+V DP +V++ G + L R+ G L + N+
Sbjct: 509 MDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQ 568
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
L G+Y C + ++ ++SA + V PP P V VE
Sbjct: 569 LHHSGKYLCTVQTTLESLSAVADIIVRGPPG---PPEDVQVE 607
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/318 (24%), Positives = 129/318 (40%), Gaps = 15/318 (4%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P + A+ L C A G+P P I W + L S + + L + +
Sbjct: 234 PETIQAAKDSSVKLECFALGNPVPDISWRR---LDGSPLPGKVKYSKSQAILEIPNFQ-Q 289
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
D G Y C A+N G ++ + A E+ + ++ + D ++ EC G P
Sbjct: 290 EDEGFYECIASNLRGRNLAKGQLIFYAP--PEWEQKIQNTHLSIYDNLLWEC-KASGKPN 346
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P W KNG+ L + + R+ ++ G L+I +D+G YQC A N +
Sbjct: 347 PWYTWLKNGERL--NPEERIQ-IENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRV 403
Query: 198 IHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
+ P P + Q G + C+ P + W+R R+ +L+DG
Sbjct: 404 LASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSK-RIFLLEDG 462
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
SL++ N+ +D G Y+C A N G +G L V + I + P+ ++V G C
Sbjct: 463 SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQ 522
Query: 316 ATGRP--EPTMFWSVEGN 331
+ P E W G+
Sbjct: 523 VSHDPSIEVVFVWFFNGD 540
Score = 46.4 bits (105), Expect = 6e-04
Identities = 66/300 (22%), Positives = 106/300 (35%), Gaps = 20/300 (6%)
Query: 201 KPYLITGPEDVVAQ---TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+P P DV+ + S V C G P P W+++ + + LD GSL
Sbjct: 25 RPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSL 84
Query: 258 RLDNVIL-ADEGEYSCEAENSVGAV-SASGYLT-VYDPPSINLSPNSVNVESGNVARFTC 314
+++ D G Y C A N +G + S L Y + ++V+V G C
Sbjct: 85 AINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLC 144
Query: 315 TATGR-PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
+ + W+ N + R T L I + +D N C
Sbjct: 145 GPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETG------NLYIAKVEPSDVGN-YTCF 197
Query: 374 AVNYAGSSFVRGKLT--VTSDD----DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
N V+G T V D + P I P S C A+ P P
Sbjct: 198 ITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVP 257
Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
I+W + + + + L + + + D G Y C+AS+ G+ + G L+ +P
Sbjct: 258 DISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAP 317
>BC067107-1|AAH67107.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 162 bits (394), Expect = 6e-39
Identities = 126/404 (31%), Positives = 178/404 (44%), Gaps = 29/404 (7%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
S E + +E DV V QP L+CR G+P I W K GV + TH ++L G L
Sbjct: 39 SAELAFAVEPSDDVAVPG-QPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLM 97
Query: 68 F--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
R G SD G Y C A N +G SR A + A + +F + P++ +G
Sbjct: 98 IRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATM-SDFHVHPQATVGEEGGVA 156
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
+C G P+P + W+KN + D + R L+ G L I R D G + C+A N
Sbjct: 157 RFQC-QIHGLPKPLITWEKNRVPIDTDNE-RYTLLPKGVLQITGLRAEDGGIFHCVASNI 214
Query: 186 AGTRESAIATLKI-------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
A R S A L + + +P ++ GPE++ + +C G+P P V W R
Sbjct: 215 ASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRL 274
Query: 239 AGGGNMPLG--RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPS 294
G P+G ++VL G+L + +V + G Y C A V +A G L V P
Sbjct: 275 DG---RPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAE 331
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
P S++ +G A FTC A G P P + W G ++ PG H + T
Sbjct: 332 FVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQ--VLGPG-----GHVRLKNNNST 384
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
LTI+ D C A N AGSS +LTV + P P
Sbjct: 385 -LTISGIGPEDEA-IYQCVAENSAGSSQASARLTVLWAEGLPGP 426
Score = 134 bits (323), Expect = 2e-30
Identities = 134/518 (25%), Positives = 208/518 (40%), Gaps = 59/518 (11%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +EP + G +VL+C G+P + W+KNG L + L+ G+L+I+
Sbjct: 44 FAVEPSDDVAVPGQPIVLDCRV-EGTPPVRITWRKNGVEL--PESTHSTLLANGSLMIRH 100
Query: 170 AR------QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
R +D G Y+C+A+N G S A ++ P+ V + G FQC
Sbjct: 101 FRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQC 160
Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVS 282
++ G P P + W ++ + R +L G L++ + D G + C A N +S
Sbjct: 161 QIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRIS 220
Query: 283 ASGYLTV-------YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
LTV Y P+I + P ++ + A C ATG P P + WS R I
Sbjct: 221 HGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIG 280
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSD 392
G+ G L I+D S VC+A N G+ R G+L V
Sbjct: 281 VEGIQ---------VLGTGNLIISDVTVQHS-GVYVCAA-NRPGTRVRRTAQGRLVV--- 326
Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGT 451
+ P P + + P + A+F C A P P + W G+ L H R N+ T
Sbjct: 327 --QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNST 384
Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI 511
L + + D Y CVA + G S L V LPGPP
Sbjct: 385 LTISGIGPEDEAIYQCVAENSAGSSQASARLTV-------------LWAEGLPGPPRNVR 431
Query: 512 THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTH 571
+V+ T V +SWS+ + I+GY + + R+ P +++ Q
Sbjct: 432 AVSVSSTEVRVSWSE-PLANTKEIIGYVLHI--RKAAD----PPELEYQEAVSKSTFQ-- 482
Query: 572 YVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
++V L P Y F ++ G S S + + T+G+
Sbjct: 483 HLVSDLEPSTAYSFYIKAYTPRGASSASVPTLASTLGE 520
Score = 107 bits (258), Expect = 2e-22
Identities = 88/289 (30%), Positives = 131/289 (45%), Gaps = 21/289 (7%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSDAGVYWCEA 87
A C+ G P P I W K V + +D R ++LP G L+ T R D G++ C A
Sbjct: 156 ARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKG---VLQITGLRAE-DGGIFHCVA 211
Query: 88 TNSYGTARSRNATLHV------AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
+N S A L V A + PE+ T VLEC+ G+P P V
Sbjct: 212 SNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVAT-GNPRPIVS 270
Query: 142 WKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR--ESAIATLKI 198
W + +G+ + +G + ++ GNL+I D +G Y C A N GTR +A L +
Sbjct: 271 WSRLDGRPIGVEG---IQVLGTGNLIISDVTVQHSGVYVCAA-NRPGTRVRRTAQGRLVV 326
Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257
+ P+ + G++ F C+ G+P P V W ++ G P G V++ ++ S L
Sbjct: 327 QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKN-GQVLGPGGHVRLKNNNSTL 385
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
+ + DE Y C AENS G+ AS LTV + P +V S
Sbjct: 386 TISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVS 434
Score = 38.7 bits (86), Expect = 0.13
Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 9/128 (7%)
Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPL-DNITIEYEMKTILHSNDVSGFEIT 695
+ A + S +++ W + N + G ++ R D +EY+ S ++
Sbjct: 430 VRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAV---SKSTFQHLVS 486
Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP- 754
L T Y F++ + + S +A TL + P PP+++ +L ++++ L W P
Sbjct: 487 DLEPSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPPLSVR--VLGSSSLQLLWEPW 544
Query: 755 PELQLQNG 762
P L G
Sbjct: 545 PRLAQHEG 552
>BC042054-1|AAH42054.1| 814|Homo sapiens putative neuronal cell
adhesion molecule protein.
Length = 814
Score = 162 bits (394), Expect = 6e-39
Identities = 126/404 (31%), Positives = 178/404 (44%), Gaps = 29/404 (7%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
S E + +E DV V QP L+CR G+P I W K GV + TH ++L G L
Sbjct: 39 SAELAFAVEPSDDVAVPG-QPIVLDCRVEGTPPVRITWRKNGVELPESTHSTLLANGSLM 97
Query: 68 F--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
R G SD G Y C A N +G SR A + A + +F + P++ +G
Sbjct: 98 IRHFRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATM-SDFHVHPQATVGEEGGVA 156
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
+C G P+P + W+KN + D + R L+ G L I R D G + C+A N
Sbjct: 157 RFQC-QIHGLPKPLITWEKNRVPIDTDNE-RYTLLPKGVLQITGLRAEDGGIFHCVASNI 214
Query: 186 AGTRESAIATLKI-------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
A R S A L + + +P ++ GPE++ + +C G+P P V W R
Sbjct: 215 ASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRL 274
Query: 239 AGGGNMPLG--RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV--SASGYLTVYDPPS 294
G P+G ++VL G+L + +V + G Y C A V +A G L V P
Sbjct: 275 DG---RPIGVEGIQVLGTGNLIISDVTVQHSGVYVCAANRPGTRVRRTAQGRLVVQAPAE 331
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
P S++ +G A FTC A G P P + W G ++ PG H + T
Sbjct: 332 FVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQ--VLGPG-----GHVRLKNNNST 384
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
LTI+ D C A N AGSS +LTV + P P
Sbjct: 385 -LTISGIGPEDEA-IYQCVAENSAGSSQASARLTVLWAEGLPGP 426
Score = 134 bits (323), Expect = 2e-30
Identities = 134/518 (25%), Positives = 208/518 (40%), Gaps = 59/518 (11%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +EP + G +VL+C G+P + W+KNG L + L+ G+L+I+
Sbjct: 44 FAVEPSDDVAVPGQPIVLDCRV-EGTPPVRITWRKNGVEL--PESTHSTLLANGSLMIRH 100
Query: 170 AR------QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
R +D G Y+C+A+N G S A ++ P+ V + G FQC
Sbjct: 101 FRLEPGGSPSDEGDYECVAQNRFGLVVSRKARIQAATMSDFHVHPQATVGEEGGVARFQC 160
Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVS 282
++ G P P + W ++ + R +L G L++ + D G + C A N +S
Sbjct: 161 QIHGLPKPLITWEKNRVPIDTDNERYTLLPKGVLQITGLRAEDGGIFHCVASNIASIRIS 220
Query: 283 ASGYLTV-------YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
LTV Y P+I + P ++ + A C ATG P P + WS R I
Sbjct: 221 HGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVATGNPRPIVSWSRLDGRPIG 280
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSD 392
G+ G L I+D S VC+A N G+ R G+L V
Sbjct: 281 VEGIQ---------VLGTGNLIISDVTVQHS-GVYVCAA-NRPGTRVRRTAQGRLVV--- 326
Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGT 451
+ P P + + P + A+F C A P P + W G+ L H R N+ T
Sbjct: 327 --QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKNGQVLGPGGHVRLKNNNST 384
Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI 511
L + + D Y CVA + G S L V LPGPP
Sbjct: 385 LTISGIGPEDEAIYQCVAENSAGSSQASARLTV-------------LWAEGLPGPPRNVR 431
Query: 512 THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTH 571
+V+ T V +SWS+ + I+GY + + R+ P +++ Q
Sbjct: 432 AVSVSSTEVRVSWSE-PLANTKEIIGYVLHI--RKAAD----PPELEYQEAVSKSTFQ-- 482
Query: 572 YVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
++V L P Y F ++ G S S + + T+G+
Sbjct: 483 HLVSDLEPSTAYSFYIKAYTPRGASSASVPTLASTLGE 520
Score = 107 bits (258), Expect = 2e-22
Identities = 88/289 (30%), Positives = 131/289 (45%), Gaps = 21/289 (7%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRVHSDAGVYWCEA 87
A C+ G P P I W K V + +D R ++LP G L+ T R D G++ C A
Sbjct: 156 ARFQCQIHGLPKPLITWEKNRVPIDTDNERYTLLPKG---VLQITGLRAE-DGGIFHCVA 211
Query: 88 TNSYGTARSRNATLHV------AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
+N S A L V A + PE+ T VLEC+ G+P P V
Sbjct: 212 SNIASIRISHGARLTVSGSGSGAYKEPAILVGPENLTLTVHQTAVLECVAT-GNPRPIVS 270
Query: 142 WKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR--ESAIATLKI 198
W + +G+ + +G + ++ GNL+I D +G Y C A N GTR +A L +
Sbjct: 271 WSRLDGRPIGVEG---IQVLGTGNLIISDVTVQHSGVYVCAA-NRPGTRVRRTAQGRLVV 326
Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257
+ P+ + G++ F C+ G+P P V W ++ G P G V++ ++ S L
Sbjct: 327 QAPAEFVQHPQSISRPAGTTAMFTCQAQGEPPPHVTWLKN-GQVLGPGGHVRLKNNNSTL 385
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
+ + DE Y C AENS G+ AS LTV + P +V S
Sbjct: 386 TISGIGPEDEAIYQCVAENSAGSSQASARLTVLWAEGLPGPPRNVRAVS 434
Score = 38.7 bits (86), Expect = 0.13
Identities = 28/128 (21%), Positives = 55/128 (42%), Gaps = 9/128 (7%)
Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPL-DNITIEYEMKTILHSNDVSGFEIT 695
+ A + S +++ W + N + G ++ R D +EY+ S ++
Sbjct: 430 VRAVSVSSTEVRVSWSEPLANTKEIIGYVLHIRKAADPPELEYQEAV---SKSTFQHLVS 486
Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSP- 754
L T Y F++ + + S +A TL + P PP+++ +L ++++ L W P
Sbjct: 487 DLEPSTAYSFYIKAYTPRGASSASVPTLASTLGEAPAPPPLSVR--VLGSSSLQLLWEPW 544
Query: 755 PELQLQNG 762
P L G
Sbjct: 545 PRLAQHEG 552
>AB040929-1|BAA96020.1| 920|Homo sapiens KIAA1496 protein protein.
Length = 920
Score = 162 bits (394), Expect = 6e-39
Identities = 198/773 (25%), Positives = 321/773 (41%), Gaps = 92/773 (11%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLRE------EFRLE---PESKQSAQGDTVVLE 128
SD G Y C T+ AR + + + + E ++E PE+ +A+G TV LE
Sbjct: 81 SDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPETLPAAKGSTVKLE 140
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
C G+P P + W+++ L F ++ G L I + +Q DAG Y+CIA N+ G
Sbjct: 141 CFA-LGNPIPQINWRRS-DGLPFSSKIKLRKFSGV-LEIPNFQQEDAGSYECIAENSRG- 196
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ A L + KP+ + +DV S+ ++CR G P P W ++ G + L
Sbjct: 197 KNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKN--GAALVLEE 254
Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPPSINLSPNS--VNVE 305
+++G+L + N+ + D G + C AEN G V +S L V P + +P V V+
Sbjct: 255 RTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQ 314
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G++ C P W +G+ ++ ++ + + DG L I + K D
Sbjct: 315 VGSLVSLDCKPRASPRALSSWK-KGDVSV------QEHERISLLNDGG--LKIANVTKAD 365
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
+ T C A N G + L VT P IT PSN + + + PC P
Sbjct: 366 A-GTYTCMAENQFGKANGTTHLVVTE-----PTRITLAPSNMDVSVGESVILPCQVQHDP 419
Query: 426 --EPIIAWYFEGEALIQ-----NHRRNV--TNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
+ I WYF G AL +H V ++ G L+++++ SG Y C+
Sbjct: 420 LLDIIFTWYFNG-ALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCM-------- 470
Query: 477 VWSGALLVDSPINPNIHFFRAAD--VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
V +G V S AAD V PGPP +TDT+ LSW + K S
Sbjct: 471 VQTGVDSVSS----------AADLIVRGSPGPPENVKVDEITDTTAQLSWKE-GKDNHSP 519
Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
++ Y ++ + ++ VI + H V L P + Y F V N G
Sbjct: 520 VISYSIQARTPFSVGWQTVTTVPE---VIDGKTHTA--TVVELNPWVEYEFRVVASNKIG 574
Query: 595 LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
PS S+ V +++ + V+ R+ + +I P+ E
Sbjct: 575 GGEPSLPSEKVRT-EEAVPEVPPSEVNGGGGSRSEL-------VITWDPVPE-------E 619
Query: 655 ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSG--FEITSLRKYTKYEFFLIPFYK 712
+ N G + FRPL T ++T++ S D F S+ Y+ YE + +
Sbjct: 620 LQNGEGF-GYVVAFRPLGVTT---WIQTVVTSPDTPRYVFRNESIVPYSPYEVKVGVYNN 675
Query: 713 KFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVN 772
K EG S + ++ P P + L+++ + + W+ +L NG + GY V
Sbjct: 676 KGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLSNGHLLGYEVRY- 734
Query: 773 WLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
W +S + ++ TS + L S ++Y + A G GPFS V
Sbjct: 735 WNGGGKEESSSKMKVAGNE-TSARLRGLKSNLAYYTAVRAYNSAGAGPFSATV 786
Score = 135 bits (326), Expect = 1e-30
Identities = 115/409 (28%), Positives = 182/409 (44%), Gaps = 37/409 (9%)
Query: 96 SRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD 154
SR A L A L E F+ + S S +G VVL C PP S E + W N + D
Sbjct: 3 SREAKLQFAYL-ENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEED 61
Query: 155 SRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG------ 207
SR + + G+L I +D G Y C+ + + + ++ + G
Sbjct: 62 SRRFVSQETGHLYISKVEPSDVGNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKI 121
Query: 208 ----PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLD-DGSLRLDN 261
PE + A GS+V +C G+P+P + WRRS G +P ++K+ G L + N
Sbjct: 122 EVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDG---LPFSSKIKLRKFSGVLEIPN 178
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
D G Y C AENS G A G LT Y P V + + + C A+G+P+
Sbjct: 179 FQQEDAGSYECIAENSRGKNVARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPK 238
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
P+ W G ++ T + +G LTI++ DS C A N G
Sbjct: 239 PSYRWLKNGAALVL--------EERTQIENG--ALTISNLSVTDS-GMFQCIAENKHGLV 287
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIK--SMAVFPCTAICTPEPIIAWYFEGEALI 439
+ +L V + P + P + + ++ S+ C +P + +W +G+ +
Sbjct: 288 YSSAELKVVAS----APDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWK-KGDVSV 342
Query: 440 QNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
Q H R ++ NDG L + ++ K+D+GTYTC+A ++ GK + L+V P
Sbjct: 343 QEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEP 391
Score = 115 bits (276), Expect = 1e-24
Identities = 89/321 (27%), Positives = 138/321 (42%), Gaps = 13/321 (4%)
Query: 2 SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
SD + E ++ P + A+ L C A G+P P I W + L S +
Sbjct: 110 SDGVMGEYEPKIEVQFPETLPAAKGSTVKLECFALGNPIPQINWRRSDGLPFSSKIKLRK 169
Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
+G L DAG Y C A NS G +R + A + + + + A
Sbjct: 170 FSGVLEIPNFQQ----EDAGSYECIAENSRGKNVARGRLTYYA--KPHWVQLIKDVEIAV 223
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
D++ EC G P+P+ W KNG L+ + ++ ++ G L I + TD+G +QCI
Sbjct: 224 EDSLYWECRAS-GKPKPSYRWLKNGAALVLEERTQ---IENGALTISNLSVTDSGMFQCI 279
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPED--VVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
A N G S+ + P P V Q GS V+ C+ P W++
Sbjct: 280 AENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKG- 338
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
R+ +L+DG L++ NV AD G Y+C AEN G + + +L V +P I L+P
Sbjct: 339 DVSVQEHERISLLNDGGLKIANVTKADAGTYTCMAENQFGKANGTTHLVVTEPTRITLAP 398
Query: 300 NSVNVESGNVARFTCTATGRP 320
++++V G C P
Sbjct: 399 SNMDVSVGESVILPCQVQHDP 419
Score = 33.1 bits (72), Expect = 6.2
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 7/63 (11%)
Query: 494 FFRAADVSSLPGPPTKP---ITHNVTDTSVTLSWSQNNKI-GSSSILGYQVEVFSRETLS 549
F +V++ PP++P + N TDT V L+W Q + S + GY +VF R T S
Sbjct: 782 FSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGY--KVFYR-TSS 838
Query: 550 GNN 552
NN
Sbjct: 839 QNN 841
>AB003592-1|BAA82612.1| 1028|Homo sapiens neural adhesion molecule
NB-3 protein.
Length = 1028
Score = 162 bits (394), Expect = 6e-39
Identities = 137/490 (27%), Positives = 211/490 (43%), Gaps = 38/490 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+ P+ + PLD++ + LNC A G PSP RW + G + GG +
Sbjct: 30 QEPHDVIFPLDLSKSE---VILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSLAI 86
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLE 128
+ H D G+Y C ATN GT SR A L A + E+F + S S +G VVL
Sbjct: 87 NSPH--TDQDIGMYQCLATNLLGTILSRKAKLQFAYI-EDFETKTRSTVSVREGQGVVLL 143
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187
C PP + + W N L D+R + + GNL I +D G Y C N
Sbjct: 144 CGPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETGNLYIAKVEPSDVGNYTCFITNKEA 203
Query: 188 TRESAIATLKI---------HIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
R + +P + + PE + A SSV +C G+P+PD+ WRR
Sbjct: 204 QRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVPDISWRR 263
Query: 238 SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
G +P G+VK + L + N DEG Y C A N G A G L Y PP
Sbjct: 264 -LDGSPLP-GKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWE 321
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
+ ++ + + C A+G+P P W G R + P + T + +T+L
Sbjct: 322 QKIQNTHLSIYDNLLWECKASGKPNPWYTWLKNGER--LNPEERIQIENGTLI---ITML 376
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT--LPIKSM 414
++D+ C+A N + +L V + P + P + + +
Sbjct: 377 NVSDS------GVYQCAAENKYQIIYANAELRVLAS----APDFSKSPVKKKSFVQVGGD 426
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
V C P I+W E L Q+ R + DG+L + ++ +SD+G+YTC+A+++ G
Sbjct: 427 IVIGCKPNAFPRAAISWKRGTETLRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFG 486
Query: 475 KYVWSGALLV 484
+G+L+V
Sbjct: 487 TAKNTGSLIV 496
Score = 106 bits (254), Expect = 6e-22
Identities = 164/729 (22%), Positives = 279/729 (38%), Gaps = 85/729 (11%)
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
PE+ Q+A+ +V LEC G+P P++ W++ +G L G + + L I + +Q
Sbjct: 234 PETIQAAKDSSVKLECFA-LGNPVPDISWRRLDGSPL--PGKVK-YSKSQAILEIPNFQQ 289
Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
D G Y+CIA N G R A L + P ++ ++ ++C+ G P P
Sbjct: 290 EDEGFYECIASNLRG-RNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKASGKPNPW 348
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-D 291
W ++ N P R+++ ++G+L + + ++D G Y C AEN + A+ L V
Sbjct: 349 YTWLKNGERLN-PEERIQI-ENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRVLAS 406
Query: 292 PPSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P + SP V+ G C P + W G T+ R +
Sbjct: 407 APDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWK-RGTETL------RQSKRIFLL 459
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
DG L I + ++D+ + C A N G++ G L V + +IT PS +
Sbjct: 460 EDGS--LKIYNITRSDA-GSYTCIATNQFGTAKNTGSLIV-----KERTVITVPPSKMDV 511
Query: 410 PIKSMAVFPCTAICTP--EPIIAWYFEGEALIQN----HRRNVTND--GTLVLKDLDKSD 461
+ V PC P E + W+F G+ + H + + G L+++++
Sbjct: 512 TVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHH 571
Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT 521
SG Y C + ++V P PGPP +++ T+
Sbjct: 572 SGKYLCTVQTTLESLSAVADIIVRGP----------------PGPPEDVQVEDISSTTSQ 615
Query: 522 LSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
LSW S +++F+ +T TP S GW +A V ++ G
Sbjct: 616 LSWRAGPDNNSP------IQIFTIQT----RTPF-SVGWQAVA--------TVPEILNGK 656
Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVEL-IE 640
TY V GLS V G NS+ G S R + + I
Sbjct: 657 TYNATVV-----GLSPWVEYEFRVVAG---NSIGIGEPSEPSELLRTKASVPVVAPVNIH 708
Query: 641 ATPIDSKTIKLMWEILNFYYLEG----LFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696
+ + WE + G I FRP+ + T E + + S+ + S
Sbjct: 709 GGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKEKVSSVESSRFV-YRNES 767
Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
+ + +E + + + EG S + + +D P P + + + + + W+
Sbjct: 768 IIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSLQSFSASEMEVSWNAIA 827
Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
G + GY V+ W D + +SM+ T+ +T L + Y + A
Sbjct: 828 WNRNTGRVLGYEVLY-WTD-DSKESMIGKIRVSGNVTTKNITGLKANTIYFASVRAYNTA 885
Query: 817 GLGPFSQKV 825
G GP S V
Sbjct: 886 GTGPSSPPV 894
Score = 99 bits (238), Expect = 5e-20
Identities = 80/282 (28%), Positives = 124/282 (43%), Gaps = 22/282 (7%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C+A G P+P W K G + + R + G L SD+GVY C A N Y
Sbjct: 339 CKASGKPNPWYTWLKNGERL-NPEERIQIENGTLIITMLNV----SDSGVYQCAAENKYQ 393
Query: 93 TARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
+ NA L V +F P K+S G +V+ C P P + WK+ +TL
Sbjct: 394 IIYA-NAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGC-KPNAFPRAAISWKRGTETLR 451
Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
R+ L++ G+L I + ++DAG Y CIA N GT ++ +L + + + P
Sbjct: 452 --QSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNT-GSLIVKERTVITVPPSK 508
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-------RVKVLDDGSLRLDNVI 263
+ G S+ C+V DP +V++ G + L R+ G L + N+
Sbjct: 509 MDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQ 568
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
L G+Y C + ++ ++SA + V PP P V VE
Sbjct: 569 LHHSGKYLCTVQTTLESLSAVADIIVRGPPG---PPEDVQVE 607
Score = 91.5 bits (217), Expect = 2e-17
Identities = 78/318 (24%), Positives = 129/318 (40%), Gaps = 15/318 (4%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P + A+ L C A G+P P I W + L S + + L + +
Sbjct: 234 PETIQAAKDSSVKLECFALGNPVPDISWRR---LDGSPLPGKVKYSKSQAILEIPNFQ-Q 289
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
D G Y C A+N G ++ + A E+ + ++ + D ++ EC G P
Sbjct: 290 EDEGFYECIASNLRGRNLAKGQLIFYAP--PEWEQKIQNTHLSIYDNLLWEC-KASGKPN 346
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P W KNG+ L + + R+ ++ G L+I +D+G YQC A N +
Sbjct: 347 PWYTWLKNGERL--NPEERIQ-IENGTLIITMLNVSDSGVYQCAAENKYQIIYANAELRV 403
Query: 198 IHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
+ P P + Q G + C+ P + W+R R+ +L+DG
Sbjct: 404 LASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRGTETLRQSK-RIFLLEDG 462
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
SL++ N+ +D G Y+C A N G +G L V + I + P+ ++V G C
Sbjct: 463 SLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGESIVLPCQ 522
Query: 316 ATGRP--EPTMFWSVEGN 331
+ P E W G+
Sbjct: 523 VSHDPSIEVVFVWFFNGD 540
Score = 46.4 bits (105), Expect = 6e-04
Identities = 66/300 (22%), Positives = 106/300 (35%), Gaps = 20/300 (6%)
Query: 201 KPYLITGPEDVVAQ---TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
+P P DV+ + S V C G P P W+++ + + LD GSL
Sbjct: 25 RPIFTQEPHDVIFPLDLSKSEVILNCAANGYPSPHYRWKQNGTDIDFTMSYHYRLDGGSL 84
Query: 258 RLDNVIL-ADEGEYSCEAENSVGAV-SASGYLT-VYDPPSINLSPNSVNVESGNVARFTC 314
+++ D G Y C A N +G + S L Y + ++V+V G C
Sbjct: 85 AINSPHTDQDIGMYQCLATNLLGTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLC 144
Query: 315 TATGR-PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
+ + W+ N + R T L I + +D N C
Sbjct: 145 GPPPHFGDLSYAWTFNDNPLYVQEDNRRFVSQETG------NLYIAKVEPSDVGN-YTCF 197
Query: 374 AVNYAGSSFVRGKLT--VTSDD----DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
N V+G T V D + P I P S C A+ P P
Sbjct: 198 ITNKEAQRSVQGPPTPLVQRTDGVMGEYEPKIEVRFPETIQAAKDSSVKLECFALGNPVP 257
Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
I+W + + + + L + + + D G Y C+AS+ G+ + G L+ +P
Sbjct: 258 DISWRRLDGSPLPGKVKYSKSQAILEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAP 317
>AF304305-1|AAN32614.1| 1842|Homo sapiens Down syndrome cell adhesion
molecule like-protein 1b protein.
Length = 1842
Score = 160 bits (389), Expect = 2e-38
Identities = 206/832 (24%), Positives = 339/832 (40%), Gaps = 74/832 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I ++T + +NCR G P +I+WYK +L+ D HR ++ G L+
Sbjct: 294 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGT--LKL 350
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
T + D G Y C + S++ +HVAV E ++ G + + C+
Sbjct: 351 TDVQKGMDEGEYLCSVLIQPQLSISQS--VHVAVKVPPLIQPFEFPPASIGQLLYIPCVV 408
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G + W+K+GQ ++ + + +L I G CIA NAA T
Sbjct: 409 SSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAAT-V 467
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN------M 244
S L + + P + P + G + C V G P P V+W+ + G GN +
Sbjct: 468 SRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPV 527
Query: 245 PL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302
PL GR+++L + SL + +V+ D G Y C+A N VG +S S +LTV P I PN+
Sbjct: 528 PLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTT 587
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG----VTVLTI 358
G+ CTA G + W E T+I P R +A A D V+ L +
Sbjct: 588 IAIKGHAKELNCTARGERPIIIRW--EKGDTVIDP--DRVMRYAIATKDNGDEVVSTLKL 643
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
D+ DS C A+N G +LTV D PP + +++ ++ F
Sbjct: 644 KPADRGDS-VFFSCHAINSYGEDRGLIQLTVQEPPD-PPELEIREVKARSMNLRWTQRFD 701
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+I T I + RN++ N +V DL + + + ++ G+
Sbjct: 702 GNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIV--DLHPASVYSIRMYSFNKIGR 759
Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSS 534
S L + + + ++ GPP VT S+ ++W K + +
Sbjct: 760 SEPSKELTI------------STEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGV 807
Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
I GYQ+ RE G+N V + Y + +L Y +V+ N G
Sbjct: 808 IRGYQIGY--RENSPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 862
Query: 595 LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
+GPS + T +D S R +T + + + P S
Sbjct: 863 -TGPSSSEINATTLEDVPS-------QPPENVRALSITSDVAVISWSEPPRS-------- 906
Query: 655 ILNFYYLEGLFIYFRPLDNITIEY-EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKK 713
LN L+G + F L + E+ EM+ I + + E+ + K+T Y ++ + +
Sbjct: 907 TLN-GVLKGYRVIFWSL-YVDGEWGEMQNITTTRE--RVELRGMEKFTNYSVQVLAYTQA 962
Query: 714 FEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
+G S+ QT +DVP GPP I+ + ++V + W PP NG+I Y + +
Sbjct: 963 GDGVRSSVLYIQTKEDVP-GPPAGIKAVPSSASSVVVSWLPP--TKPNGVIRKYTIFCS- 1018
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+ + + T + + +L G Y + +AA T G G S+KV
Sbjct: 1019 -SPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKV 1069
Score = 128 bits (309), Expect = 1e-28
Identities = 206/850 (24%), Positives = 334/850 (39%), Gaps = 109/850 (12%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRS---ILPAGGLF 67
P I+ + V + +L C A G+P P + W +V D +HR+ + G
Sbjct: 197 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 256
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
G D GVY C A N G+A + A ++V R A DT++
Sbjct: 257 SHMNVTGPQIRDGGVYRCTARNLVGSAEYQ-ARINVRG-PPSIRAMRNITAVAGRDTLI- 313
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IARN 184
C G P ++ W K+ LL + R + + G L + D ++ D G Y C + +
Sbjct: 314 NCRVI-GYPYYSIKWYKDA--LLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQP 370
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA---- 239
+S +K+ P LI E A G + C V +P + WR+
Sbjct: 371 QLSISQSVHVAVKV---PPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVII 427
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
G + + + + SL++ +V L G +C A N+ VS L V PP + P
Sbjct: 428 SGSGVTIESKEFMS--SLQISSVSLKHNGNDTCIASNAAATVSRERQLIVRVPPRFVVQP 485
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
N+ + G C+ G P P + W +G+ + +YH + + +L
Sbjct: 486 NNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSG-------NPQQYHPVPLTGRIQILPN 538
Query: 359 NDT----DKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIKS 413
+ + +C A N G+ + LTV + P +IT+ P N T+ IK
Sbjct: 539 SSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTV-----KIPAMITSHP-NTTIAIKG 592
Query: 414 MA-VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTND------GTLVLKDLDKSDS 462
A CTA PII + +G+ +I R T D TL LK D+ DS
Sbjct: 593 HAKELNCTA-RGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDS 651
Query: 463 GTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTL 522
++C A + +G+ L V P P PP I V S+ L
Sbjct: 652 VFFSCHAINSYGEDRGLIQLTVQEP----------------PDPPELEI-REVKARSMNL 694
Query: 523 SWSQNNKIGSSSILGYQVEVFSR-ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGI 581
W+Q G+S I G+ +E ++ ++ + RN I+ ++Q + V L P
Sbjct: 695 RWTQRFD-GNSIITGFDIEYKNKSDSWDFKQSTRN------ISPTINQANIV--DLHPAS 745
Query: 582 TYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEA 641
Y + + N G S P S +T+ STE D +
Sbjct: 746 VYSIRMYSFNKIGRSEP---SKELTI---------------STE---EAAPDGPPMDVTL 784
Query: 642 TPIDSKTIKLMWEI----LNFYYLEGLFIYFRP-LDNITIEYEMKTILHSNDVSGFEITS 696
P+ S++I++ W+ L + G I +R +Y + + + D + + +
Sbjct: 785 QPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDN 844
Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
L+K+ +Y + F + G S+ A TL+DVP PP N+ + + + WS P
Sbjct: 845 LKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPP 904
Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
NG++ GY V+ L V + TT + L + +YSVQ+ A T
Sbjct: 905 RSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVEL--RGMEKFTNYSVQVLAYTQA 962
Query: 817 GLGPFSQKVY 826
G G S +Y
Sbjct: 963 GDGVRSSVLY 972
Score = 120 bits (290), Expect = 2e-26
Identities = 115/453 (25%), Positives = 184/453 (40%), Gaps = 36/453 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C A G P PAIRW K G + +D+ + G L + R D+G Y CE TN+
Sbjct: 34 LPCTAPGYPIPAIRWLKDGRPLPADSRWTKRITG----LTISDLRTE-DSGTYICEVTNT 88
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
+G+A + + + L L P+ ++ G TV+L C GSPE + W +N + +L
Sbjct: 89 FGSAEATGILMVIDPLH--VTLTPKKLKTGIGSTVILSCALT-GSPEFTIRWYRNTELVL 145
Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA-RNAAGTRESAIATLKIHIKPYLITGPE 209
D + + L+I A+++ +G YQC A R A ++ AI L+ P +++
Sbjct: 146 PDEAISIRGLSNETLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALE-DGTPRIVSSFS 204
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVI-- 263
+ V G + C G P P V W G+ + + D ++ NV
Sbjct: 205 EKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGP 264
Query: 264 -LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
+ D G Y C A N VG+ + V PPSI N + +G C G P
Sbjct: 265 QIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRN-ITAVAGRDTLINCRVIGYPYY 323
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W + ++ P H VF+ T L + D K +CS + S
Sbjct: 324 SIKWYKD---ALLLP-----DNHRQVVFENGT-LKLTDVQKGMDEGEYLCSVLIQPQLSI 374
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQN 441
+ + PP+I I + PC PI I W +G+ +I
Sbjct: 375 SQSVHVAV----KVPPLI-QPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISG 429
Query: 442 HRRNVTND---GTLVLKDLDKSDSGTYTCVASS 471
+ + +L + + +G TC+AS+
Sbjct: 430 SGVTIESKEFMSSLQISSVSLKHNGNDTCIASN 462
Score = 92.3 bits (219), Expect = 1e-17
Identities = 119/466 (25%), Positives = 189/466 (40%), Gaps = 47/466 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP IRWY+ LV+ D SI L + + HS G Y C AT
Sbjct: 123 LSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHS--GAYQCFATRK 180
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
TA+ A + + K G+ L C +G+P P V W + + ++
Sbjct: 181 AQTAQDF-AIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAA-KGAPPPTVTWALDDEPIV 238
Query: 151 FDGDSRMH---LVDG---GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-PY 203
DG R + + DG ++ + + D G Y+C ARN G+ E +I+++ P
Sbjct: 239 RDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQA---RINVRGPP 295
Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNV 262
I ++ A G CRV G P + W + A +P R V ++G+L+L +V
Sbjct: 296 SIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL--LLPDNHRQVVFENGTLKLTDV 353
Query: 263 ILA-DEGEYSCEAENSVG-AVSASGYLTVYDPPSIN---LSPNSVNVESGNVARFTCTAT 317
DEGEY C ++S S ++ V PP I P S+ G + C +
Sbjct: 354 QKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASI----GQLLYIPCVVS 409
Query: 318 GRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
P W +G I G++ + + ++ L I+ + N C A N
Sbjct: 410 SGDMPIRITWRKDGQVIISGSGVTIESK------EFMSSLQISSVSLKHNGND-TCIASN 462
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEG 435
A + +L V R PP P+NQ V C+ P P + W + +G
Sbjct: 463 AAATVSRERQLIV-----RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKG 517
Query: 436 EALIQNH-------RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
Q + R + + +L+++ + + D G Y C AS+ G
Sbjct: 518 SGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 563
Score = 81.4 bits (192), Expect = 2e-14
Identities = 76/312 (24%), Positives = 128/312 (41%), Gaps = 29/312 (9%)
Query: 208 PEDVVAQ---TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
PEDV S+ C G P+P + W + G +P L + ++
Sbjct: 18 PEDVGTSLYFVNDSLQLPCTAPGYPIPAIRWLKD--GRPLPADSRWTKRITGLTISDLRT 75
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
D G Y CE N+ G+ A+G L V DP + L+P + G+ +C TG PE T+
Sbjct: 76 EDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGIGSTVILSCALTGSPEFTI 135
Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
W N ++ P D+ + T+L I K+ S C A A ++
Sbjct: 136 RW--YRNTELVLP----DEAISIRGLSNETLL-ITSAQKSHS-GAYQCFATRKAQTA--- 184
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NH 442
+ + +D P I+++ P + ++ C A P P + W + E +++ +H
Sbjct: 185 QDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLM-CAAKGAPPPTVTWALDDEPIVRDGSH 243
Query: 443 RRN--VTNDGTLV----LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFR 496
R N +DGT + + D G Y C A + G + + V P P+I R
Sbjct: 244 RTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGP--PSIRAMR 301
Query: 497 AADVSSLPGPPT 508
+++++ G T
Sbjct: 302 --NITAVAGRDT 311
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/186 (23%), Positives = 79/186 (42%), Gaps = 8/186 (4%)
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
+++ T S ++ I L + Y + F K +PS T + PDGPP+
Sbjct: 721 DFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM 780
Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
++ + + + ++ + W P+ +LQNG+I GY + + P + +I S +
Sbjct: 781 DVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEV 839
Query: 797 MT--NLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGD 854
T NL Y V + A G GP S ++ + + D+ S+ P N + D
Sbjct: 840 YTLDNLKKFAQYGVVVQAFNRAGTGPSSSEI-----NATTLEDVPSQPPENVRALSITSD 894
Query: 855 FVMETW 860
+ +W
Sbjct: 895 VAVISW 900
Score = 51.6 bits (118), Expect = 2e-05
Identities = 63/241 (26%), Positives = 102/241 (42%), Gaps = 35/241 (14%)
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
+AV AG K+T+ P II+ G + T +K + + PC ++ P P + W
Sbjct: 1055 AAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRL-PCNSVGDPAPAVKWT 1113
Query: 433 FEGE-----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ E + HR TN GTL+L+ + DSG YTC A++ G LLV P
Sbjct: 1114 KDSEDSAIPVSMDGHRLIHTN-GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP 1172
Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
P P ++ + +S+TL+W + G SSI G+ ++ +S +
Sbjct: 1173 ----------------PDQPRLTVS-KTSASSITLTWIPGDN-GGSSIRGFVLQ-YSVD- 1212
Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
NS W + + + + SL G Y + +NS G S + ++ T
Sbjct: 1213 --------NSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTH 1264
Query: 608 G 608
G
Sbjct: 1265 G 1265
Score = 43.2 bits (97), Expect = 0.006
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
Query: 8 SGEAPY-IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK----GGVLVVSDTHRSILP 62
+G+AP II VT + L C + G P+PA++W K + V D HR ++
Sbjct: 1074 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHR-LIH 1132
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G LRA D+G Y C ATN+ G
Sbjct: 1133 TNGTLLLRAVKA---EDSGYYTCTATNTGG 1159
Score = 38.7 bits (86), Expect = 0.13
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
V C GDP P V W + + +P+ G + +G+L L V D G Y+C A
Sbjct: 1096 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1155
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G + L V PP
Sbjct: 1156 NTGGFDTIIVNLLVQVPP 1173
Score = 37.5 bits (83), Expect = 0.29
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 10/99 (10%)
Query: 134 GSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G P P V W K+ + + DG +H G L+++ + D+G Y C A N G
Sbjct: 1104 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHT--NGTLLLRAVKAEDSGYYTCTATNTGGF- 1160
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
++ I L + + P P V++T +S + GD
Sbjct: 1161 DTIIVNLLVQVPP---DQPRLTVSKTSASSITLTWIPGD 1196
>AF304304-1|AAN32613.1| 2053|Homo sapiens Down syndrome cell adhesion
molecule like-protein 1a protein.
Length = 2053
Score = 160 bits (389), Expect = 2e-38
Identities = 206/832 (24%), Positives = 339/832 (40%), Gaps = 74/832 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I ++T + +NCR G P +I+WYK +L+ D HR ++ G L+
Sbjct: 505 PPSIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLL-PDNHRQVVFENGT--LKL 561
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
T + D G Y C + S++ +HVAV E ++ G + + C+
Sbjct: 562 TDVQKGMDEGEYLCSVLIQPQLSISQS--VHVAVKVPPLIQPFEFPPASIGQLLYIPCVV 619
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G + W+K+GQ ++ + + +L I G CIA NAA T
Sbjct: 620 SSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNDTCIASNAAAT-V 678
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN------M 244
S L + + P + P + G + C V G P P V+W+ + G GN +
Sbjct: 679 SRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPV 738
Query: 245 PL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSV 302
PL GR+++L + SL + +V+ D G Y C+A N VG +S S +LTV P I PN+
Sbjct: 739 PLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTT 798
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG----VTVLTI 358
G+ CTA G + W E T+I P R +A A D V+ L +
Sbjct: 799 IAIKGHAKELNCTARGERPIIIRW--EKGDTVIDP--DRVMRYAIATKDNGDEVVSTLKL 854
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
D+ DS C A+N G +LTV D PP + +++ ++ F
Sbjct: 855 KPADRGDS-VFFSCHAINSYGEDRGLIQLTVQEPPD-PPELEIREVKARSMNLRWTQRFD 912
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+I T I + RN++ N +V DL + + + ++ G+
Sbjct: 913 GNSIITGFDIEYKNKSDSWDFKQSTRNISPTINQANIV--DLHPASVYSIRMYSFNKIGR 970
Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK-IGSSS 534
S L + + + ++ GPP VT S+ ++W K + +
Sbjct: 971 SEPSKELTI------------STEEAAPDGPPMDVTLQPVTSQSIQVTWKAPKKELQNGV 1018
Query: 535 ILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
I GYQ+ RE G+N V + Y + +L Y +V+ N G
Sbjct: 1019 IRGYQIGY--RENSPGSN---GQYSIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAG 1073
Query: 595 LSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE 654
+GPS + T +D S R +T + + + P S
Sbjct: 1074 -TGPSSSEINATTLEDVPS-------QPPENVRALSITSDVAVISWSEPPRS-------- 1117
Query: 655 ILNFYYLEGLFIYFRPLDNITIEY-EMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKK 713
LN L+G + F L + E+ EM+ I + + E+ + K+T Y ++ + +
Sbjct: 1118 TLN-GVLKGYRVIFWSL-YVDGEWGEMQNITTTRE--RVELRGMEKFTNYSVQVLAYTQA 1173
Query: 714 FEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
+G S+ QT +DVP GPP I+ + ++V + W PP NG+I Y + +
Sbjct: 1174 GDGVRSSVLYIQTKEDVP-GPPAGIKAVPSSASSVVVSWLPP--TKPNGVIRKYTIFCS- 1229
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+ + + T + + +L G Y + +AA T G G S+KV
Sbjct: 1230 -SPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKV 1280
Score = 139 bits (337), Expect = 5e-32
Identities = 135/524 (25%), Positives = 224/524 (42%), Gaps = 47/524 (8%)
Query: 9 GEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGL 66
G + Y + L VT + + C A GSPS A+RWY G + H + A G
Sbjct: 22 GTSLYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGT 81
Query: 67 FFL-----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L A + +H + Y+C A N+ G RS N + AV RE + + E ++S +
Sbjct: 82 LQLYPFSPSAFNSFIHDND--YFCTAENAAGKIRSPNIRVK-AVFREPYTVRVEDQRSMR 138
Query: 122 GDTVVLECLPPRGSPE--PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRY 178
G+ V +CL P E V W+K+ +++ + R + G L I D ++ DA Y
Sbjct: 139 GNVAVFKCLIPFLGQEYVSVVSWEKDTVSII--PEHRFFITYHGGLYISDVQKEDALSTY 196
Query: 179 QCIARN--AAGTRESAIATLKI----HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
+CI ++ + TR+S A L + P ++ G G +V C G P+P
Sbjct: 197 RCITKHKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPA 256
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ W + G +P L + ++ D G Y CE N+ G+ A+G L V DP
Sbjct: 257 IRWLKD--GRPLPADSRWTKRITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDP 314
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
+ L+P + G+ +C TG PE T+ W N ++ P D+ +
Sbjct: 315 LHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRW--YRNTELVLP----DEAISIRGLSN 368
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
T+L I K+ S C A A ++ + + +D P I+++ P +
Sbjct: 369 ETLL-ITSAQKSHS-GAYQCFATRKAQTA---QDFAIIALEDGTPRIVSSFSEKVVNPGE 423
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQ--NHRRN--VTNDGTLV----LKDLDKSDSGT 464
++ C A P P + W + E +++ +HR N +DGT + + D G
Sbjct: 424 QFSLM-CAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGV 482
Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPT 508
Y C A + G + + V P P+I R +++++ G T
Sbjct: 483 YRCTARNLVGSAEYQARINVRGP--PSIRAMR--NITAVAGRDT 522
Score = 129 bits (311), Expect = 7e-29
Identities = 205/851 (24%), Positives = 338/851 (39%), Gaps = 111/851 (13%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRS----ILPAGGL 66
P I+ + V + +L C A G+P P + W +V D +HR+ + +
Sbjct: 408 PRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI 467
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
++ T ++ D GVY C A N G+A + A ++V R A DT++
Sbjct: 468 SYMNVTGPQIR-DGGVYRCTARNLVGSAEYQ-ARINVRG-PPSIRAMRNITAVAGRDTLI 524
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ-TDAGRYQC--IAR 183
C G P ++ W K+ LL + R + + G L + D ++ D G Y C + +
Sbjct: 525 -NCRVI-GYPYYSIKWYKDA--LLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQ 580
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWRRSA--- 239
+S +K+ P LI E A G + C V +P + WR+
Sbjct: 581 PQLSISQSVHVAVKV---PPLIQPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVI 637
Query: 240 -GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
G + + + + SL++ +V L G +C A N+ VS L V PP +
Sbjct: 638 ISGSGVTIESKEFMS--SLQISSVSLKHNGNDTCIASNAAATVSRERQLIVRVPPRFVVQ 695
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
PN+ + G C+ G P P + W +G+ + +YH + + +L
Sbjct: 696 PNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSG-------NPQQYHPVPLTGRIQILP 748
Query: 358 INDT----DKNDSRNTIVCSAVNYAGSSFVRGK-LTVTSDDDRPPPIITNGPSNQTLPIK 412
+ + +C A N G+ + LTV + P +IT+ P N T+ IK
Sbjct: 749 NSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTV-----KIPAMITSHP-NTTIAIK 802
Query: 413 SMA-VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTND------GTLVLKDLDKSD 461
A CTA PII + +G+ +I R T D TL LK D+ D
Sbjct: 803 GHAKELNCTA-RGERPIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGD 861
Query: 462 SGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVT 521
S ++C A + +G+ L V P P PP I V S+
Sbjct: 862 SVFFSCHAINSYGEDRGLIQLTVQEP----------------PDPPELEI-REVKARSMN 904
Query: 522 LSWSQNNKIGSSSILGYQVEVFSR-ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPG 580
L W+Q G+S I G+ +E ++ ++ + RN I+ ++Q + V L P
Sbjct: 905 LRWTQRFD-GNSIITGFDIEYKNKSDSWDFKQSTRN------ISPTINQANIV--DLHPA 955
Query: 581 ITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIE 640
Y + + N G S P S +T+ STE D +
Sbjct: 956 SVYSIRMYSFNKIGRSEP---SKELTI---------------STE---EAAPDGPPMDVT 994
Query: 641 ATPIDSKTIKLMWEI----LNFYYLEGLFIYFRP-LDNITIEYEMKTILHSNDVSGFEIT 695
P+ S++I++ W+ L + G I +R +Y + + + D + +
Sbjct: 995 LQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLD 1054
Query: 696 SLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPP 755
+L+K+ +Y + F + G S+ A TL+DVP PP N+ + + + WS P
Sbjct: 1055 NLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEP 1114
Query: 756 ELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI 815
NG++ GY V+ L V + TT + L + +YSVQ+ A T
Sbjct: 1115 PRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVEL--RGMEKFTNYSVQVLAYTQ 1172
Query: 816 IGLGPFSQKVY 826
G G S +Y
Sbjct: 1173 AGDGVRSSVLY 1183
Score = 117 bits (281), Expect = 3e-25
Identities = 154/608 (25%), Positives = 237/608 (38%), Gaps = 37/608 (6%)
Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG--TARSRNAT 100
+ W K V ++ + I GGL+ + + Y C + Y T +S A
Sbjct: 159 VSWEKDTVSIIPEHRFFITYHGGLYI---SDVQKEDALSTYRCITKHKYSGETRQSNGAR 215
Query: 101 LHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
L V E + S + G TV L C G P P + W K+G+ L DSR
Sbjct: 216 LSVTDPAESIPTILDGFHSQEVWAGHTVELPCTAS-GYPIPAIRWLKDGRPL--PADSRW 272
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT-GPEDVVAQTG 216
G L I D R D+G Y C N G+ E A L + I P +T P+ + G
Sbjct: 273 TKRITG-LTISDLRTEDSGTYICEVTNTFGSAE-ATGILMV-IDPLHVTLTPKKLKTGIG 329
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVILADEGEYSCEA 274
S+V C + G P + W R+ +P + + L + +L + + + G Y C A
Sbjct: 330 STVILSCALTGSPEFTIRWYRNTELV-LPDEAISIRGLSNETLLITSAQKSHSGAYQCFA 388
Query: 275 ENSVGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
+ + D P I S + V G C A G P PT+ W+++ +
Sbjct: 389 TRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALD-DEP 447
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSD 392
I+ G R + + DG T+ +N T + C+A N GS+ + ++ V
Sbjct: 448 IVRDGSHRTNQYTMS--DGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV--- 502
Query: 393 DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
R PP I N T + C I P I WY + L NHR+ V +GTL
Sbjct: 503 --RGPPSI-RAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTL 559
Query: 453 VLKDLDKS-DSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI 511
L D+ K D G Y C + + S ++ V + P I F +S+ P
Sbjct: 560 KLTDVQKGMDEGEYLCSVLIQPQLSI-SQSVHVAVKVPPLIQPFEFPP-ASIGQLLYIPC 617
Query: 512 THNVTDTSVTLSWSQNNK--IGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQ 569
+ D + ++W ++ + I S + E S +S + N IA
Sbjct: 618 VVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGND-TCIASNAAA 676
Query: 570 THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD-SVTVGDDSNSLWE-GTGVSNSTEYR 627
T + LI + F+V+ N G+ G + V + SV +W+ G N +Y
Sbjct: 677 TVSRERQLIVRVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYH 736
Query: 628 NNILTDHI 635
LT I
Sbjct: 737 PVPLTGRI 744
Score = 91.5 bits (217), Expect = 2e-17
Identities = 119/466 (25%), Positives = 188/466 (40%), Gaps = 47/466 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L+C GSP IRWY+ LV+ D SI L + + HS G Y C AT
Sbjct: 334 LSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLLITSAQKSHS--GAYQCFATRK 391
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
TA+ A + + K G+ L C +G+P P V W + + ++
Sbjct: 392 AQTAQDF-AIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAA-KGAPPPTVTWALDDEPIV 449
Query: 151 FDGDSRMH---LVDGGNLVIQDA---RQTDAGRYQCIARNAAGTRESAIATLKIHIK-PY 203
DG R + + DG + + + D G Y+C ARN G+ E +I+++ P
Sbjct: 450 RDGSHRTNQYTMSDGTTISYMNVTGPQIRDGGVYRCTARNLVGSAEYQA---RINVRGPP 506
Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNV 262
I ++ A G CRV G P + W + A +P R V ++G+L+L +V
Sbjct: 507 SIRAMRNITAVAGRDTLINCRVIGYPYYSIKWYKDAL--LLPDNHRQVVFENGTLKLTDV 564
Query: 263 ILA-DEGEYSCEAENSVG-AVSASGYLTVYDPPSIN---LSPNSVNVESGNVARFTCTAT 317
DEGEY C ++S S ++ V PP I P S+ G + C +
Sbjct: 565 QKGMDEGEYLCSVLIQPQLSISQSVHVAVKVPPLIQPFEFPPASI----GQLLYIPCVVS 620
Query: 318 GRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
P W +G I G++ + + ++ L I+ + N C A N
Sbjct: 621 SGDMPIRITWRKDGQVIISGSGVTIESK------EFMSSLQISSVSLKHNGND-TCIASN 673
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-YFEG 435
A + +L V R PP P+NQ V C+ P P + W + +G
Sbjct: 674 AAATVSRERQLIV-----RVPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKG 728
Query: 436 EALIQNH-------RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
Q + R + + +L+++ + + D G Y C AS+ G
Sbjct: 729 SGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVG 774
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/186 (23%), Positives = 79/186 (42%), Gaps = 8/186 (4%)
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
+++ T S ++ I L + Y + F K +PS T + PDGPP+
Sbjct: 932 DFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPM 991
Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
++ + + + ++ + W P+ +LQNG+I GY + + P + +I S +
Sbjct: 992 DVTLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYR-ENSPGSNGQYSIVEMKATGDSEV 1050
Query: 797 MT--NLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGD 854
T NL Y V + A G GP S ++ + + D+ S+ P N + D
Sbjct: 1051 YTLDNLKKFAQYGVVVQAFNRAGTGPSSSEI-----NATTLEDVPSQPPENVRALSITSD 1105
Query: 855 FVMETW 860
+ +W
Sbjct: 1106 VAVISW 1111
Score = 51.6 bits (118), Expect = 2e-05
Identities = 63/241 (26%), Positives = 102/241 (42%), Gaps = 35/241 (14%)
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
+AV AG K+T+ P II+ G + T +K + + PC ++ P P + W
Sbjct: 1266 AAVTSAGRGNSSEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRL-PCNSVGDPAPAVKWT 1324
Query: 433 FEGE-----ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ E + HR TN GTL+L+ + DSG YTC A++ G LLV P
Sbjct: 1325 KDSEDSAIPVSMDGHRLIHTN-GTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP 1383
Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
P P ++ + +S+TL+W + G SSI G+ ++ +S +
Sbjct: 1384 ----------------PDQPRLTVS-KTSASSITLTWIPGDN-GGSSIRGFVLQ-YSVD- 1423
Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
NS W + + + + SL G Y + +NS G S + ++ T
Sbjct: 1424 --------NSEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGRISEIIEAKTH 1475
Query: 608 G 608
G
Sbjct: 1476 G 1476
Score = 43.2 bits (97), Expect = 0.006
Identities = 31/90 (34%), Positives = 43/90 (47%), Gaps = 9/90 (10%)
Query: 8 SGEAPY-IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK----GGVLVVSDTHRSILP 62
+G+AP II VT + L C + G P+PA++W K + V D HR ++
Sbjct: 1285 AGKAPAKIISFGGTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHR-LIH 1343
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G LRA D+G Y C ATN+ G
Sbjct: 1344 TNGTLLLRAVKA---EDSGYYTCTATNTGG 1370
Score = 38.7 bits (86), Expect = 0.13
Identities = 25/78 (32%), Positives = 35/78 (44%), Gaps = 3/78 (3%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDGSLRLDNVILADEGEYSCEAE 275
V C GDP P V W + + +P+ G + +G+L L V D G Y+C A
Sbjct: 1307 VRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTAT 1366
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G + L V PP
Sbjct: 1367 NTGGFDTIIVNLLVQVPP 1384
Score = 37.5 bits (83), Expect = 0.29
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 10/99 (10%)
Query: 134 GSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G P P V W K+ + + DG +H G L+++ + D+G Y C A N G
Sbjct: 1315 GDPAPAVKWTKDSEDSAIPVSMDGHRLIHT--NGTLLLRAVKAEDSGYYTCTATNTGGF- 1371
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
++ I L + + P P V++T +S + GD
Sbjct: 1372 DTIIVNLLVQVPP---DQPRLTVSKTSASSITLTWIPGD 1407
>Z21488-1|CAA79696.1| 1018|Homo sapiens contactin protein.
Length = 1018
Score = 159 bits (385), Expect = 7e-38
Identities = 139/497 (27%), Positives = 210/497 (42%), Gaps = 48/497 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQ---PATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPA 63
G P EQP++ +LNCRA SP P +W G V + SD + +
Sbjct: 38 GFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMV--- 94
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
GG + + DAG+Y+C A+N+YG RS ATL L E + +G
Sbjct: 95 GGNLVINNPDKQ--KDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGK 152
Query: 124 TVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCI 181
+VL C PP P+ Y W N + D R + GNL I + +D G Y C
Sbjct: 153 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 212
Query: 182 ARNAAGTR---ESAIATLKI---HIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
+ + T+ I + I KPY ++ +DV A G +VT +C G+P+PD
Sbjct: 213 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPD 272
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
+ WR+ MP ++ G+ L++ N+ L DEG Y CEAEN G + V
Sbjct: 273 IRWRKVL--EPMP-STAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQA 329
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P N V+ G+ + C ATG+P PT+ W G YH
Sbjct: 330 FPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGY-----------AYHKGE--- 375
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L + D ++ C A N G+ + +L + + P N + L
Sbjct: 376 ----LRLYDV-TFENAGMYQCIAENTYGAIYANAELKILA---LAPTFEMNPMKKKILAA 427
Query: 412 K-SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
K + C P+P +W E L+ + R + DG+L + ++ ++D G YTC A
Sbjct: 428 KGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAE 487
Query: 471 SRHGKYVWSGALLVDSP 487
+ GK +G L++ P
Sbjct: 488 NNRGKANSTGTLVITDP 504
Score = 115 bits (276), Expect = 1e-24
Identities = 119/446 (26%), Positives = 188/446 (42%), Gaps = 36/446 (8%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+ Q DV Q TL C A G+P P IRW K VL + I +G + L+ +
Sbjct: 244 IVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAV--LKIFN 299
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
++ D G+Y CEA N G + + A ++V E +++ G + C+
Sbjct: 300 IQLE-DEGIYECEAENIRGKDKHQ-ARIYVQAFPEWVEHINDTEVDI-GSDLYWPCVAT- 355
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G P P + W KNG + G L + D +AG YQCIA N G A
Sbjct: 356 GKPIPTIRWLKNG-----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIY-AN 403
Query: 194 ATLKI-HIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
A LKI + P P + ++A G V +C+ P P W + + R+
Sbjct: 404 AELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEW-LVNSSRIL 462
Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
+ +DGSL ++N+ D G Y+C AEN+ G +++G L + DP I L+P + ++ G A
Sbjct: 463 IWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENA 522
Query: 311 RFTCTATGRP--EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KNDSR 367
C A+ P + T WS G +I Y + D L I + K+ R
Sbjct: 523 TMQCAASFDPALDLTFVWSFNG--YVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGR 580
Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
T C+A +S L V R PP G + + S+A+ P
Sbjct: 581 YT--CTAQTIVDNSSASADLVV-----RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSP 633
Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLV 453
I + + + ++ + ++ D ++
Sbjct: 634 ISKYTIQTKTILSDDWKDAKTDPPII 659
Score = 112 bits (269), Expect = 8e-24
Identities = 167/723 (23%), Positives = 274/723 (37%), Gaps = 101/723 (13%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G V LEC G+P P++ W+K + + + G L I + + D G Y+C
Sbjct: 256 GQNVTLECFA-LGNPVPDIRWRKVLEPMPSTAEIS---TSGAVLKIFNIQLEDEGIYECE 311
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
A N G ++ A + + P + D GS + + C G P+P + W ++
Sbjct: 312 AENIRG-KDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG-- 368
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPN 300
G LRL +V + G Y C AEN+ GA+ A+ L + P+ ++P
Sbjct: 369 --------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 420
Query: 301 SVNVESGNVAR--FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ + R C P+P WS +G ++ + DG L I
Sbjct: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWS-KGTEWLV------NSSRILIWEDGS--LEI 471
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N+ +ND C A N G + G L +T P I P N + + A
Sbjct: 472 NNITRNDG-GIYTCFAENNRGKANSTGTLVITD-----PTRIILAPINADITVGENATMQ 525
Query: 419 CTAICTP--EPIIAWYFEGEALIQN-----HRRN--VTNDGTLVLKDLDKSDSGTYTCVA 469
C A P + W F G + N ++RN + ++G L++++ +G YTC A
Sbjct: 526 CAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTA 585
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+ S L+V P PGPP ++ TSV L+WS+ +
Sbjct: 586 QTIVDNSSASADLVVRGP----------------PGPPGGLRIEDIRATSVALTWSRGSD 629
Query: 530 IGSSSILGYQVE---VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
S I Y ++ + S + P G + AR V LIP + Y F
Sbjct: 630 -NHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAV--------DLIPWMEYEFR 680
Query: 587 VRTENSHGLSGPSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPID 645
V N+ G PS S+ + T G N G RN LT I P+
Sbjct: 681 VVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGG---RNRELT------ITWAPLS 731
Query: 646 SKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI---TSLRKYTK 702
+ + N + G + F+P D E K + +N +G + ++ T
Sbjct: 732 RE-----YHYGNNF---GYIVAFKPFDG----EEWKKVTVTNPDTGRYVHKDETMSPSTA 779
Query: 703 YEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNG 762
++ + F K +G S V + D P P + + +L+++ + + W +
Sbjct: 780 FQVKVKAFNNKGDGPYSLLAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE----HVLEK 835
Query: 763 IITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
I+ Y + W ++ + T Q S + NL Y +++ A G GP S
Sbjct: 836 IVESYQIRY-WAAHDKEEAANRVQVT-SQEYSARLENLLPDTQYFIEVGACNSAGCGPPS 893
Query: 823 QKV 825
+
Sbjct: 894 DMI 896
Score = 39.9 bits (89), Expect = 0.054
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSM---AVFPCTAICTPEPIIAWYFE-GEALIQNHRR 444
V+ +D PI P N P +S+ C A +P P+ W G+ + + R
Sbjct: 32 VSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRY 91
Query: 445 NVTNDGTLVLKDLDKS-DSGTYTCVASSRHG 474
++ G LV+ + DK D+G Y C+AS+ +G
Sbjct: 92 SMVG-GNLVINNPDKQKDAGIYYCLASNNYG 121
>U07820-1|AAA67921.1| 1007|Homo sapiens h-contactin 2 precursor
protein.
Length = 1007
Score = 159 bits (385), Expect = 7e-38
Identities = 139/497 (27%), Positives = 210/497 (42%), Gaps = 48/497 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQ---PATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPA 63
G P EQP++ +LNCRA SP P +W G V + SD + +
Sbjct: 27 GFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMV--- 83
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
GG + + DAG+Y+C A+N+YG RS ATL L E + +G
Sbjct: 84 GGNLVINNPDKQ--KDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGK 141
Query: 124 TVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCI 181
+VL C PP P+ Y W N + D R + GNL I + +D G Y C
Sbjct: 142 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 201
Query: 182 ARNAAGTR---ESAIATLKI---HIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
+ + T+ I + I KPY ++ +DV A G +VT +C G+P+PD
Sbjct: 202 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPD 261
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
+ WR+ MP ++ G+ L++ N+ L DEG Y CEAEN G + V
Sbjct: 262 IRWRKVL--EPMP-STAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQA 318
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P N V+ G+ + C ATG+P PT+ W G YH
Sbjct: 319 FPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGY-----------AYHKGE--- 364
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L + D ++ C A N G+ + +L + + P N + L
Sbjct: 365 ----LRLYDV-TFENAGMYQCIAENTYGAIYANAELKILA---LAPTFEMNPMKKKILAA 416
Query: 412 K-SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
K + C P+P +W E L+ + R + DG+L + ++ ++D G YTC A
Sbjct: 417 KGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAE 476
Query: 471 SRHGKYVWSGALLVDSP 487
+ GK +G L++ P
Sbjct: 477 NNRGKANSTGTLVITDP 493
Score = 115 bits (276), Expect = 1e-24
Identities = 119/446 (26%), Positives = 188/446 (42%), Gaps = 36/446 (8%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+ Q DV Q TL C A G+P P IRW K VL + I +G + L+ +
Sbjct: 233 IVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAV--LKIFN 288
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
++ D G+Y CEA N G + + A ++V E +++ G + C+
Sbjct: 289 IQLE-DEGIYECEAENIRGKDKHQ-ARIYVQAFPEWVEHINDTEVDI-GSDLYWPCVAT- 344
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G P P + W KNG + G L + D +AG YQCIA N G A
Sbjct: 345 GKPIPTIRWLKNG-----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIY-AN 392
Query: 194 ATLKI-HIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
A LKI + P P + ++A G V +C+ P P W + + R+
Sbjct: 393 AELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEW-LVNSSRIL 451
Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
+ +DGSL ++N+ D G Y+C AEN+ G +++G L + DP I L+P + ++ G A
Sbjct: 452 IWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENA 511
Query: 311 RFTCTATGRP--EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KNDSR 367
C A+ P + T WS G +I Y + D L I + K+ R
Sbjct: 512 TMQCAASFDPALDLTFVWSFNG--YVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGR 569
Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
T C+A +S L V R PP G + + S+A+ P
Sbjct: 570 YT--CTAQTIVDNSSASADLVV-----RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSP 622
Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLV 453
I + + + ++ + ++ D ++
Sbjct: 623 ISKYTIQTKTILSDDWKDAKTDPPII 648
Score = 112 bits (269), Expect = 8e-24
Identities = 167/723 (23%), Positives = 274/723 (37%), Gaps = 101/723 (13%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G V LEC G+P P++ W+K + + + G L I + + D G Y+C
Sbjct: 245 GQNVTLECFA-LGNPVPDIRWRKVLEPMPSTAEIS---TSGAVLKIFNIQLEDEGIYECE 300
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
A N G ++ A + + P + D GS + + C G P+P + W ++
Sbjct: 301 AENIRG-KDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG-- 357
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPN 300
G LRL +V + G Y C AEN+ GA+ A+ L + P+ ++P
Sbjct: 358 --------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 409
Query: 301 SVNVESGNVAR--FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ + R C P+P WS +G ++ + DG L I
Sbjct: 410 KKKILAAKGGRVIIECKPKAAPKPKFSWS-KGTEWLV------NSSRILIWEDGS--LEI 460
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N+ +ND C A N G + G L +T P I P N + + A
Sbjct: 461 NNITRNDG-GIYTCFAENNRGKANSTGTLVITD-----PTRIILAPINADITVGENATMQ 514
Query: 419 CTAICTP--EPIIAWYFEGEALIQN-----HRRN--VTNDGTLVLKDLDKSDSGTYTCVA 469
C A P + W F G + N ++RN + ++G L++++ +G YTC A
Sbjct: 515 CAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTA 574
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+ S L+V P PGPP ++ TSV L+WS+ +
Sbjct: 575 QTIVDNSSASADLVVRGP----------------PGPPGGLRIEDIRATSVALTWSRGSD 618
Query: 530 IGSSSILGYQVE---VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
S I Y ++ + S + P G + AR V LIP + Y F
Sbjct: 619 -NHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAV--------DLIPWMEYEFR 669
Query: 587 VRTENSHGLSGPSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPID 645
V N+ G PS S+ + T G N G RN LT I P+
Sbjct: 670 VVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGG---RNRELT------ITWAPLS 720
Query: 646 SKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI---TSLRKYTK 702
+ + N + G + F+P D E K + +N +G + ++ T
Sbjct: 721 RE-----YHYGNNF---GYIVAFKPFDG----EEWKKVTVTNPDTGRYVHKDETMSPSTA 768
Query: 703 YEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNG 762
++ + F K +G S V + D P P + + +L+++ + + W +
Sbjct: 769 FQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE----HVLEK 824
Query: 763 IITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
I+ Y + W ++ + T Q S + NL Y +++ A G GP S
Sbjct: 825 IVESYQIRY-WAAHDKEEAANRVQVT-SQEYSARLENLLPDTQYFIEVGACNSAGCGPPS 882
Query: 823 QKV 825
+
Sbjct: 883 DMI 885
Score = 41.5 bits (93), Expect = 0.018
Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 6/93 (6%)
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSM---AVFPCTAICTPEPIIAWYFE-GEALIQNH 442
L V+ +D PI P N P +S+ C A +P P+ W G+ + +
Sbjct: 19 LAVSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSD 78
Query: 443 RRNVTNDGTLVLKDLDKS-DSGTYTCVASSRHG 474
R ++ G LV+ + DK D+G Y C+AS+ +G
Sbjct: 79 RYSMVG-GNLVINNPDKQKDAGIYYCLASNNYG 110
>U07819-1|AAA67920.1| 1018|Homo sapiens h-contactin 1 precursor
protein.
Length = 1018
Score = 159 bits (385), Expect = 7e-38
Identities = 139/497 (27%), Positives = 210/497 (42%), Gaps = 48/497 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQ---PATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPA 63
G P EQP++ +LNCRA SP P +W G V + SD + +
Sbjct: 38 GFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMV--- 94
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
GG + + DAG+Y+C A+N+YG RS ATL L E + +G
Sbjct: 95 GGNLVINNPDKQ--KDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGK 152
Query: 124 TVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCI 181
+VL C PP P+ Y W N + D R + GNL I + +D G Y C
Sbjct: 153 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 212
Query: 182 ARNAAGTR---ESAIATLKI---HIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
+ + T+ I + I KPY ++ +DV A G +VT +C G+P+PD
Sbjct: 213 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPD 272
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
+ WR+ MP ++ G+ L++ N+ L DEG Y CEAEN G + V
Sbjct: 273 IRWRKVL--EPMP-STAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQA 329
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P N V+ G+ + C ATG+P PT+ W G YH
Sbjct: 330 FPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGY-----------AYHKGE--- 375
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L + D ++ C A N G+ + +L + + P N + L
Sbjct: 376 ----LRLYDV-TFENAGMYQCIAENTYGAIYANAELKILA---LAPTFEMNPMKKKILAA 427
Query: 412 K-SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
K + C P+P +W E L+ + R + DG+L + ++ ++D G YTC A
Sbjct: 428 KGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAE 487
Query: 471 SRHGKYVWSGALLVDSP 487
+ GK +G L++ P
Sbjct: 488 NNRGKANSTGTLVITDP 504
Score = 115 bits (276), Expect = 1e-24
Identities = 119/446 (26%), Positives = 188/446 (42%), Gaps = 36/446 (8%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+ Q DV Q TL C A G+P P IRW K VL + I +G + L+ +
Sbjct: 244 IVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAV--LKIFN 299
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
++ D G+Y CEA N G + + A ++V E +++ G + C+
Sbjct: 300 IQLE-DEGIYECEAENIRGKDKHQ-ARIYVQAFPEWVEHINDTEVDI-GSDLYWPCVAT- 355
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G P P + W KNG + G L + D +AG YQCIA N G A
Sbjct: 356 GKPIPTIRWLKNG-----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIY-AN 403
Query: 194 ATLKI-HIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
A LKI + P P + ++A G V +C+ P P W + + R+
Sbjct: 404 AELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEW-LVNSSRIL 462
Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
+ +DGSL ++N+ D G Y+C AEN+ G +++G L + DP I L+P + ++ G A
Sbjct: 463 IWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENA 522
Query: 311 RFTCTATGRP--EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KNDSR 367
C A+ P + T WS G +I Y + D L I + K+ R
Sbjct: 523 TMQCAASFDPALDLTFVWSFNG--YVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGR 580
Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
T C+A +S L V R PP G + + S+A+ P
Sbjct: 581 YT--CTAQTIVDNSSASADLVV-----RGPPGPPGGLRIEDIRATSVALTWSRGSDNHSP 633
Query: 428 IIAWYFEGEALIQNHRRNVTNDGTLV 453
I + + + ++ + ++ D ++
Sbjct: 634 ISKYTIQTKTILSDDWKDAKTDPPII 659
Score = 112 bits (269), Expect = 8e-24
Identities = 167/723 (23%), Positives = 274/723 (37%), Gaps = 101/723 (13%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G V LEC G+P P++ W+K + + + G L I + + D G Y+C
Sbjct: 256 GQNVTLECFA-LGNPVPDIRWRKVLEPMPSTAEIS---TSGAVLKIFNIQLEDEGIYECE 311
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
A N G ++ A + + P + D GS + + C G P+P + W ++
Sbjct: 312 AENIRG-KDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG-- 368
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPN 300
G LRL +V + G Y C AEN+ GA+ A+ L + P+ ++P
Sbjct: 369 --------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 420
Query: 301 SVNVESGNVAR--FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ + R C P+P WS +G ++ + DG L I
Sbjct: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWS-KGTEWLV------NSSRILIWEDGS--LEI 471
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N+ +ND C A N G + G L +T P I P N + + A
Sbjct: 472 NNITRNDG-GIYTCFAENNRGKANSTGTLVITD-----PTRIILAPINADITVGENATMQ 525
Query: 419 CTAICTP--EPIIAWYFEGEALIQN-----HRRN--VTNDGTLVLKDLDKSDSGTYTCVA 469
C A P + W F G + N ++RN + ++G L++++ +G YTC A
Sbjct: 526 CAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTA 585
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+ S L+V P PGPP ++ TSV L+WS+ +
Sbjct: 586 QTIVDNSSASADLVVRGP----------------PGPPGGLRIEDIRATSVALTWSRGSD 629
Query: 530 IGSSSILGYQVE---VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
S I Y ++ + S + P G + AR V LIP + Y F
Sbjct: 630 -NHSPISKYTIQTKTILSDDWKDAKTDPPIIEGNMEAARAV--------DLIPWMEYEFR 680
Query: 587 VRTENSHGLSGPSPVSDSV-TVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPID 645
V N+ G PS S+ + T G N G RN LT I P+
Sbjct: 681 VVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVGGGGG---RNRELT------ITWAPLS 731
Query: 646 SKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEI---TSLRKYTK 702
+ + N + G + F+P D E K + +N +G + ++ T
Sbjct: 732 RE-----YHYGNNF---GYIVAFKPFDG----EEWKKVTVTNPDTGRYVHKDETMSPSTA 779
Query: 703 YEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNG 762
++ + F K +G S V + D P P + + +L+++ + + W +
Sbjct: 780 FQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHWE----HVLEK 835
Query: 763 IITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
I+ Y + W ++ + T Q S + NL Y +++ A G GP S
Sbjct: 836 IVESYQIRY-WAAHDKEEAANRVQVT-SQEYSARLENLLPDTQYFIEVGACNSAGCGPPS 893
Query: 823 QKV 825
+
Sbjct: 894 DMI 896
Score = 39.9 bits (89), Expect = 0.054
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSM---AVFPCTAICTPEPIIAWYFE-GEALIQNHRR 444
V+ +D PI P N P +S+ C A +P P+ W G+ + + R
Sbjct: 32 VSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRY 91
Query: 445 NVTNDGTLVLKDLDKS-DSGTYTCVASSRHG 474
++ G LV+ + DK D+G Y C+AS+ +G
Sbjct: 92 SMVG-GNLVINNPDKQKDAGIYYCLASNNYG 121
>BC036569-1|AAH36569.1| 627|Homo sapiens CNTN1 protein protein.
Length = 627
Score = 159 bits (385), Expect = 7e-38
Identities = 139/497 (27%), Positives = 210/497 (42%), Gaps = 48/497 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQ---PATLNCRAGGSPSPAIRWY--KGGVLVVSDTHRSILPA 63
G P EQP++ +LNCRA SP P +W G V + SD + +
Sbjct: 38 GFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRYSMV--- 94
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
GG + + DAG+Y+C A+N+YG RS ATL L E + +G
Sbjct: 95 GGNLVINNPDKQ--KDAGIYYCLASNNYGMVRSTEATLSFGYLDPFPPEERPEVRVKEGK 152
Query: 124 TVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCI 181
+VL C PP P+ Y W N + D R + GNL I + +D G Y C
Sbjct: 153 GMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYIANVEASDKGNYSCF 212
Query: 182 ARNAAGTR---ESAIATLKI---HIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
+ + T+ I + I KPY ++ +DV A G +VT +C G+P+PD
Sbjct: 213 VSSPSITKSVFSKFIPLIPIPERTTKPYPADIVVQFKDVYALMGQNVTLECFALGNPVPD 272
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
+ WR+ MP ++ G+ L++ N+ L DEG Y CEAEN G + V
Sbjct: 273 IRWRKVL--EPMP-STAEISTSGAVLKIFNIQLEDEGIYECEAENIRGKDKHQARIYVQA 329
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P N V+ G+ + C ATG+P PT+ W G YH
Sbjct: 330 FPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNGY-----------AYHKGE--- 375
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L + D ++ C A N G+ + +L + + P N + L
Sbjct: 376 ----LRLYDV-TFENAGMYQCIAENTYGAIYANAELKILA---LAPTFEMNPMKKKILAA 427
Query: 412 K-SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
K + C P+P +W E L+ + R + DG+L + ++ ++D G YTC A
Sbjct: 428 KGGRVIIECKPKAAPKPKFSWSKGTEWLVNSSRILIWEDGSLEINNITRNDGGIYTCFAE 487
Query: 471 SRHGKYVWSGALLVDSP 487
+ GK +G L++ P
Sbjct: 488 NNRGKANSTGTLVITDP 504
Score = 114 bits (274), Expect = 2e-24
Identities = 97/322 (30%), Positives = 146/322 (45%), Gaps = 26/322 (8%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+ Q DV Q TL C A G+P P IRW K VL + I +G + L+ +
Sbjct: 244 IVVQFKDVYALMGQNVTLECFALGNPVPDIRWRK--VLEPMPSTAEISTSGAV--LKIFN 299
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
++ D G+Y CEA N G + + A ++V E +++ G + C+
Sbjct: 300 IQLE-DEGIYECEAENIRGKDKHQ-ARIYVQAFPEWVEHINDTEVDI-GSDLYWPCVAT- 355
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G P P + W KNG + G L + D +AG YQCIA N G A
Sbjct: 356 GKPIPTIRWLKNG-----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIY-AN 403
Query: 194 ATLKI-HIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
A LKI + P P + ++A G V +C+ P P W + + R+
Sbjct: 404 AELKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSWSKGTEW-LVNSSRIL 462
Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
+ +DGSL ++N+ D G Y+C AEN+ G +++G L + DP I L+P + ++ G A
Sbjct: 463 IWEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENA 522
Query: 311 RFTCTATGRP--EPTMFWSVEG 330
C A+ P + T WS G
Sbjct: 523 TMQCAASFDPALDLTFVWSFNG 544
Score = 103 bits (247), Expect = 4e-21
Identities = 84/267 (31%), Positives = 119/267 (44%), Gaps = 28/267 (10%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C A G P P IRW K G H+ L + F +AG+Y C A N+YG
Sbjct: 352 CVATGKPIPTIRWLKNGYAY----HKGELRLYDVTF---------ENAGMYQCIAENTYG 398
Query: 93 TARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
+ NA L + L F + P K+ +A+G V++EC P+ +P+P W K + L+
Sbjct: 399 AIYA-NAELKILALAPTFEMNPMKKKILAAKGGRVIIEC-KPKAAPKPKFSWSKGTEWLV 456
Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
SR+ + + G+L I + + D G Y C A N G S TL I +I P +
Sbjct: 457 --NSSRILIWEDGSLEINNITRNDGGIYTCFAENNRGKANST-GTLVITDPTRIILAPIN 513
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-------GNMPLGRVKVLD-DGSLRLDNV 262
G + T QC DP D+ + S G N+ R +LD +G L + N
Sbjct: 514 ADITVGENATMQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNA 573
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTV 289
L G Y+C A+ V SAS L V
Sbjct: 574 QLKHAGRYTCTAQTIVDNSSASADLVV 600
Score = 91.1 bits (216), Expect = 2e-17
Identities = 89/362 (24%), Positives = 145/362 (40%), Gaps = 42/362 (11%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G V LEC G+P P++ W+K + + + G L I + + D G Y+C
Sbjct: 256 GQNVTLECFA-LGNPVPDIRWRKVLEPMPSTAEIS---TSGAVLKIFNIQLEDEGIYECE 311
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
A N G ++ A + + P + D GS + + C G P+P + W ++
Sbjct: 312 AENIRG-KDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG-- 368
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPN 300
G LRL +V + G Y C AEN+ GA+ A+ L + P+ ++P
Sbjct: 369 --------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEMNPM 420
Query: 301 SVNVESGNVAR--FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ + R C P+P WS +G ++ + DG L I
Sbjct: 421 KKKILAAKGGRVIIECKPKAAPKPKFSWS-KGTEWLV------NSSRILIWEDGS--LEI 471
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N+ +ND C A N G + G L +T P I P N + + A
Sbjct: 472 NNITRNDG-GIYTCFAENNRGKANSTGTLVITD-----PTRIILAPINADITVGENATMQ 525
Query: 419 CTAICTP--EPIIAWYFEGEALIQN-----HRRN--VTNDGTLVLKDLDKSDSGTYTCVA 469
C A P + W F G + N ++RN + ++G L++++ +G YTC A
Sbjct: 526 CAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTA 585
Query: 470 SS 471
+
Sbjct: 586 QT 587
Score = 39.9 bits (89), Expect = 0.054
Identities = 27/91 (29%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSM---AVFPCTAICTPEPIIAWYFE-GEALIQNHRR 444
V+ +D PI P N P +S+ C A +P P+ W G+ + + R
Sbjct: 32 VSEEDKGFGPIFEEQPINTIYPEESLEGKVSLNCRARASPFPVYKWRMNNGDVDLTSDRY 91
Query: 445 NVTNDGTLVLKDLDKS-DSGTYTCVASSRHG 474
++ G LV+ + DK D+G Y C+AS+ +G
Sbjct: 92 SMVG-GNLVINNPDKQKDAGIYYCLASNNYG 121
>AY630258-1|AAU05741.1| 1150|Homo sapiens shen-dan protein.
Length = 1150
Score = 157 bits (380), Expect = 3e-37
Identities = 136/475 (28%), Positives = 209/475 (44%), Gaps = 41/475 (8%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
+++P DVTV R P L+C+A G + W K G + + +L G L ++ G
Sbjct: 42 VKEPQDVTVTRKDPVVLDCQAHGEVPIKVTWLKNGAKMSENKRIEVLSNGSL-YISEVEG 100
Query: 75 R--VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
R SD G Y C A N YG S+ A L ++ + F ++P S + +G C
Sbjct: 101 RRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTI-SAFEVQPISTEVHEGGVARFAC-KI 158
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
P + W+ N TL D R+ + G L I D Q D+G Y+CIA A R+S
Sbjct: 159 SSHPPAVITWEFNRTTLPMTMD-RITALPTGVLQIYDVSQRDSGNYRCIAATVAHRRKSM 217
Query: 193 IATL--------KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
A+L K P +I GP+++ +V +C G+P P + W R ++
Sbjct: 218 EASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSR-LDHKSI 276
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEA--ENSVGAVSASGYLTVYDPPSINLSPNSV 302
+ +VL +G+L + +V L G Y C A + A LTV PPS P S+
Sbjct: 277 DVFNTRVLGNGNLMISDVRLQHAGVYVCRATTPGTRNFTVAMATLTVLAPPSFVEWPESL 336
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
ARF C A G P P M W ++ R I G + Y++ L IN
Sbjct: 337 TRPRAGTARFVCQAEGIPSPKMSW-LKNGRKIHSNGRIK-MYNSK--------LVINQII 386
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN---QTLPIKSMAVFPC 419
D C A N GS R +LTV +DRP + P N +T+ ++ +
Sbjct: 387 PEDDA-IYQCMAENSQGSILSRARLTVVMSEDRP-----SAPYNVHAETMSSSAILLAWE 440
Query: 420 TAICTPEPIIAW---YFEGEAL-IQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVA 469
+ + +IA+ Y + E L + ++ + ND T ++ DL+ + + T+ VA
Sbjct: 441 RPLYNSDKVIAYSVHYMKAEGLNNEEYQVVIGNDTTHYIIDDLEPASNYTFYIVA 495
Score = 117 bits (281), Expect = 3e-25
Identities = 125/511 (24%), Positives = 191/511 (37%), Gaps = 56/511 (10%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F EP+ + D VVL+C G V W KNG + + R+ ++ G+L I +
Sbjct: 41 FVKEPQDVTVTRKDPVVLDC-QAHGEVPIKVTWLKNGAKM--SENKRIEVLSNGSLYISE 97
Query: 170 AR-----QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR 224
Q+D G YQC+A N G S A L + P G F C+
Sbjct: 98 VEGRRGEQSDEGFYQCLAMNKYGAILSQKAHLALSTISAFEVQPISTEVHEGGVARFACK 157
Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSA 283
+ P + W + M + R+ L G L++ +V D G Y C A + S
Sbjct: 158 ISSHPPAVITWEFNRTTLPMTMDRITALPTGVLQIYDVSQRDSGNYRCIAATVAHRRKSM 217
Query: 284 SGYLTV--------YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
LTV + P+I P ++ C ATG P+P + WS +++I
Sbjct: 218 EASLTVIPAKESKSFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHKSI- 276
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
D ++ + +G L I+D + VC A +F T+T
Sbjct: 277 ------DVFNTRVLGNG--NLMISDV-RLQHAGVYVCRATTPGTRNFTVAMATLTV---L 324
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
PP P + T P A F C A P P ++W G + N R + N LV+
Sbjct: 325 APPSFVEWPESLTRPRAGTARFVCQAEGIPSPKMSWLKNGRKIHSNGRIKMYN-SKLVIN 383
Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNV 515
+ D Y C+A + G + L V P P +
Sbjct: 384 QIIPEDDAIYQCMAENSQGSILSRARLTV-------------VMSEDRPSAPYNVHAETM 430
Query: 516 TDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVK 575
+ +++ L+W + S ++ Y V E L+ N VVI THY++
Sbjct: 431 SSSAILLAW-ERPLYNSDKVIAYSVHYMKAEGLN------NEEYQVVIGN--DTTHYIID 481
Query: 576 SLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
L P Y F + ++ G S +SD VT
Sbjct: 482 DLEPASNYTFYI---VAYMPMGASQMSDHVT 509
Score = 77.4 bits (182), Expect = 3e-13
Identities = 67/214 (31%), Positives = 93/214 (43%), Gaps = 15/214 (7%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
S P II P ++T + HQ L C A G+P P I W + + + +L G L
Sbjct: 231 SFHTPTIIAGPQNITTSLHQTVVLECMATGNPKPIISWSRLDHKSIDVFNTRVLGNGNLM 290
Query: 68 F--LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDT 124
+R H AGVY C AT GT A + VL +E PES + T
Sbjct: 291 ISDVRLQH------AGVYVCRATTP-GTRNFTVAMATLTVLAPPSFVEWPESLTRPRAGT 343
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
C G P P + W KNG+ + +G +M+ LVI D YQC+A N
Sbjct: 344 ARFVC-QAEGIPSPKMSWLKNGRKIHSNGRIKMY---NSKLVINQIIPEDDAIYQCMAEN 399
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
+ G+ S A L + + + P +V A+T SS
Sbjct: 400 SQGSILSR-ARLTVVMSEDRPSAPYNVHAETMSS 432
Score = 53.2 bits (122), Expect = 5e-06
Identities = 37/136 (27%), Positives = 63/136 (46%), Gaps = 11/136 (8%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+ L TKYEF + + S TL + P GPP+ +++ ++ T + W
Sbjct: 782 VQGLEPNTKYEFAVRLHVDQLSSPWSPVVYHSTLPEAPAGPPVGVKVTLIEDDTALVSWK 841
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQ---ATSLIMTNLTSGVSYSVQ 809
PP+ ++T Y ++ + K+ +A V H+ T ++ NL +G Y V+
Sbjct: 842 PPD--GPETVVTRYTIL-----YASRKAWIAGEWQVLHREGAITMALLENLVAGNVYIVK 894
Query: 810 IAAETIIGLGPFSQKV 825
I+A +G GPFS V
Sbjct: 895 ISASNEVGEGPFSNSV 910
Score = 51.2 bits (117), Expect = 2e-05
Identities = 42/186 (22%), Positives = 81/186 (43%), Gaps = 9/186 (4%)
Query: 639 IEATPIDSKTIKLMWE--ILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696
+ A + S I L WE + N + +++ + + E E + ++ ND + + I
Sbjct: 425 VHAETMSSSAILLAWERPLYNSDKVIAYSVHYMKAEGLNNE-EYQVVI-GNDTTHYIIDD 482
Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
L + Y F+++ + + S+ TL+DVP PP I + + T + + W P
Sbjct: 483 LEPASNYTFYIVAYMPMGASQMSDHVTQNTLEDVPLRPP-EISLTSRSPTDILISWLPIP 541
Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETII 816
+ + G + Y + L + ++ + T H+ ++ L Y V+I A T +
Sbjct: 542 AKYRRGQVVLYRLSFR-LSTENSIQVLELPGTTHE---YLLEGLKPDSVYLVRITAATRV 597
Query: 817 GLGPFS 822
GLG S
Sbjct: 598 GLGESS 603
>AY273815-1|AAQ16156.1| 2623|Homo sapiens bone specific CMF608
protein.
Length = 2623
Score = 156 bits (378), Expect = 5e-37
Identities = 144/502 (28%), Positives = 222/502 (44%), Gaps = 56/502 (11%)
Query: 12 PYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH----RSILPAGGL 66
P I+EQ V V + L C A G+P P++ W V + L + G
Sbjct: 1842 PVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLFLFSNGT 1901
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GD 123
++R SD G Y C AT+S G+ R R L + R+E S++ + GD
Sbjct: 1902 LYIR---NLASSDRGTYECIATSSTGSER-RVVMLTMEERVTSPRIEAASQKRTEVNFGD 1957
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQC 180
++L C G P+P + W+ + ++ S +H+ G+L I + D+G Y C
Sbjct: 1958 KLLLNC-SATGEPKPQIMWRLPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLC 2016
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ--CRVGGDPLPDVLWR-- 236
+ARN G + + + + +KP I + Q FQ C+ G P+P++ W
Sbjct: 2017 VARNKMGD-DLILMHVSLRLKPAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLP 2075
Query: 237 --------RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
A R + ++G+L + V +A+EG+Y+C A+N++G +LT
Sbjct: 2076 DGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVAEEGDYTCYAQNTLGKDEMKVHLT 2135
Query: 289 VYDP-PSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
V P I S N N +++G+ A C TG P+P +FW + N I F + R +H
Sbjct: 2136 VITAAPRIRQS-NKTNKRIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISF-SIDRYTFH 2193
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS 405
A LTIN DS VC A N +G KL V S PP+I +
Sbjct: 2194 ANGS------LTINKVKLLDS-GEYVCVARNPSGDDTKMYKLDVVSK----PPLINGLYT 2242
Query: 406 NQTLPIKSMAV------FPCTAICTPEPIIAWYFEGEALIQ----NHRRNVTNDGTLVLK 455
N+T+ IK+ AV F C A TP P + W + R V +GTL ++
Sbjct: 2243 NRTV-IKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIR 2301
Query: 456 DLDKSDSGTYTCVASSRHGKYV 477
++ SDS + CVA + G+ V
Sbjct: 2302 NVRLSDSADFICVARNEGGESV 2323
Score = 126 bits (304), Expect = 5e-28
Identities = 102/375 (27%), Positives = 165/375 (44%), Gaps = 17/375 (4%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
+ T RH +CRA G+PSP + W + + + + S + L + R+
Sbjct: 2247 IKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRL- 2305
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ-GDTVVLECLPPRGS 135
SD+ + C A N G + + +LR FR K AQ G + L C G+
Sbjct: 2306 SDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNC-SVDGN 2364
Query: 136 PEPNVYW-KKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
P P + W NG S +L+ G+ +I + DAG+Y+C ARN G E +
Sbjct: 2365 PPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEK-L 2423
Query: 194 ATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--GRV 249
L+I KP ++T P V +G S++ C G P P++ W +G + P G+
Sbjct: 2424 VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY 2483
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSPNSVNVESG 307
+ D+G+L + D G Y C+A+NSVG ++ + Y P N P S+ +G
Sbjct: 2484 ILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTG 2543
Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
+ C A G P+P + W + + + S+++ H + L I + +DS
Sbjct: 2544 AAFQLHCVALGVPKPEITWEMPDHS--LLSTASKERTHGSEQLHLQGTLVIQNPQTSDS- 2600
Query: 368 NTIVCSAVNYAGSSF 382
C+A N GS +
Sbjct: 2601 GIYKCTAKNPLGSDY 2615
Score = 125 bits (301), Expect = 1e-27
Identities = 141/501 (28%), Positives = 201/501 (40%), Gaps = 54/501 (10%)
Query: 10 EAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRS---ILPA 63
E P I+ + T+ + A L C A G+P P I W + G+ + S +LP
Sbjct: 1646 EKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN 1705
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--Q 121
G L R D G Y C A+N +GT + TL V LE +K+
Sbjct: 1706 GTLSIQRVE----IQDRGQYLCSASNLFGTDH-LHVTLSVVSYPPRI-LERRTKEITVHS 1759
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVD-GGNLVIQDARQTDAGRY 178
G TV L+C G P P V W QT++ + SR +V G LV+ + D G Y
Sbjct: 1760 GSTVELKC-RAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFY 1818
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRR 237
+C+A N G + I P ++ V+ T G S+ C G P P V W
Sbjct: 1819 KCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVL 1878
Query: 238 SAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-- 291
S G PL ++ + +G+L + N+ +D G Y C A +S G+ LT+ +
Sbjct: 1879 SDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERV 1938
Query: 292 -PPSIN-LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P I S V G+ C+ATG P+P + W + + D+ H
Sbjct: 1939 TSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVV-------DQQHRVGS 1991
Query: 350 FDGV---TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-S 405
+ V L I + DS +C A N G + L S +P I
Sbjct: 1992 WIHVYPNGSLFIGSVTEKDS-GVYLCVARNKMGDDLI---LMHVSLRLKPAKIDHKQYFR 2047
Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN--------HR-RNVT--NDGTLVL 454
Q L K V C A +P P I+W +I N HR R T N+GTL
Sbjct: 2048 KQVLHGKDFQV-DCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYF 2106
Query: 455 KDLDKSDSGTYTCVASSRHGK 475
+ ++ G YTC A + GK
Sbjct: 2107 NKVGVAEEGDYTCYAQNTLGK 2127
Score = 125 bits (301), Expect = 1e-27
Identities = 124/489 (25%), Positives = 205/489 (41%), Gaps = 39/489 (7%)
Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD----THRSILPAGGL 66
P I+E+ ++TV L CRA G PSP + W VVS+ + ++++ G
Sbjct: 1745 PRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGT 1804
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ---SAQGD 123
L H D G Y C A+N G + + + V+ + + +Q G+
Sbjct: 1805 LVL---HNLSIYDRGFYKCVASNPGG---QDSLLVKIQVIAAPPVILEQRRQVIVGTWGE 1858
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
++ L C +G+P+P+VYW + T L F +S++ L G L I++ +D G Y+
Sbjct: 1859 SLKLPC-TAKGTPQPSVYWVLSDGTEVKPLQFT-NSKLFLFSNGTLYIRNLASSDRGTYE 1916
Query: 180 CIARNAAGT-RESAIATLKIHIKPYLITGPEDVVAQT--GSSVTFQCRVGGDPLPDVLWR 236
CIA ++ G+ R + T++ + I + G + C G+P P ++WR
Sbjct: 1917 CIATSSTGSERRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWR 1976
Query: 237 ---RSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-YD 291
++ +G + V +GSL + +V D G Y C A N +G ++++
Sbjct: 1977 LPSKAVVDQQHRVGSWIHVYPNGSLFIGSVTEKDSGVYLCVARNKMGDDLILMHVSLRLK 2036
Query: 292 PPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT--- 347
P I+ V G + C A+G P P + WS+ I + D H T
Sbjct: 2037 PAKIDHKQYFRKQVLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRY 2096
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
+F+ T L N + C A N G ++ LTV + P I + +N+
Sbjct: 2097 TLFNNGT-LYFNKVGVAE-EGDYTCYAQNTLGKDEMKVHLTVIT---AAPRIRQSNKTNK 2151
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALI--QNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ AV C P+P I W +I R +G+L + + DSG Y
Sbjct: 2152 RIKAGDTAVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEY 2211
Query: 466 TCVASSRHG 474
CVA + G
Sbjct: 2212 VCVARNPSG 2220
Score = 120 bits (288), Expect = 4e-26
Identities = 120/469 (25%), Positives = 189/469 (40%), Gaps = 38/469 (8%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
A L+C G P P I W ++S R A G + D+G Y C A
Sbjct: 2159 AVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK---LLDSGEYVCVA 2215
Query: 88 TNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
N G + ++ + K +A + G+P P V W
Sbjct: 2216 RNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIM 2275
Query: 145 NGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA--TLKIHI 200
L SR+ + G L I++ R +D+ + C+ARN G + L++
Sbjct: 2276 PDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLR 2335
Query: 201 KPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLG-RVKVLDDG 255
+P P E +VAQ G S C V G+P P+++W G N P + + +G
Sbjct: 2336 RP-TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 2394
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVARFTC 314
S + D G+Y C A N VG + L + P I +P +V SG C
Sbjct: 2395 SFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHC 2454
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ G P+P + W++ + P ++ KY + D T L I + D R +C A
Sbjct: 2455 VSDGIPKPNIKWTMPSGYVVDRPQIN-GKY---ILHDNGT-LVIKEATAYD-RGNYICKA 2508
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTAICTPEPIIAWY 432
N G + + + + + PP ITN P +++ ++ A F C A+ P+P I W
Sbjct: 2509 QNSVGHTLITVPVMIVAY----PPRITNRPP-RSIVTRTGAAFQLHCVALGVPKPEITWE 2563
Query: 433 FEGEALIQNHRRNVTN-------DGTLVLKDLDKSDSGTYTCVASSRHG 474
+L+ + T+ GTLV+++ SDSG Y C A + G
Sbjct: 2564 MPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 2612
Score = 117 bits (281), Expect = 3e-25
Identities = 123/476 (25%), Positives = 204/476 (42%), Gaps = 52/476 (10%)
Query: 31 LNCRAGGSPSPAIRW-YKGGVLV-----VSDT-HRS----ILPAGGLFFLRATHGRVHSD 79
++C+A GSP P I W G ++ D+ HR+ + G L+F + ++
Sbjct: 2058 VDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGV----AE 2113
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSP 136
G Y C A N+ G + +H+ V+ R+ +K + + GDT VL+C G P
Sbjct: 2114 EGDYTCYAQNTLGKDEMK---VHLTVITAAPRIRQSNKTNKRIKAGDTAVLDC-EVTGDP 2169
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
+P ++W ++ R G+L I + D+G Y C+ARN +G ++ + L
Sbjct: 2170 KPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSGD-DTKMYKL 2228
Query: 197 KIHIKPYLITG---PEDVVAQTG---SSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--G 247
+ KP LI G V+ T S F CR G P P+V+W P
Sbjct: 2229 DVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGS 2288
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVN 303
R+ V +G+L + NV L+D ++ C A N G L V + P N +
Sbjct: 2289 RITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIV 2348
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
+ G C+ G P P + W + N T G Y +G + I+ T +
Sbjct: 2349 AQLGKSTALNCSVDGNPPPEIIW-ILPNGTRFSNG--PQSYQYLIASNGSFI--ISKTTR 2403
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAI 422
D+ C+A N G ++ KL + + + P I+T P + + +S+++ C +
Sbjct: 2404 EDA-GKYRCAARNKVG--YIE-KLVIL-EIGQKPVILTYAPGTVKGISGESLSLH-CVSD 2457
Query: 423 CTPEPIIAWYFEGEALIQNHRRN----VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P+P I W ++ + N + ++GTLV+K+ D G Y C A + G
Sbjct: 2458 GIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVG 2513
Score = 91.9 bits (218), Expect = 1e-17
Identities = 70/273 (25%), Positives = 117/273 (42%), Gaps = 21/273 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
LNC G+P P I W S+ +++ ++ + G F + T DAG Y C A
Sbjct: 2357 LNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKT---TREDAGKYRCAA 2413
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + L + P + + G+++ L C+ G P+PN+ W
Sbjct: 2414 RNKVGYIE-KLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSD-GIPKPNIKWTMPSG 2471
Query: 148 TLL----FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
++ +G +H D G LVI++A D G Y C A+N+ G + + + P
Sbjct: 2472 YVVDRPQINGKYILH--DNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 2529
Query: 204 LIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SAGGGNMPLGRVKVLDDGS 256
+ P +V +TG++ C G P P++ W S G ++ G+
Sbjct: 2530 ITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGT 2589
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L + N +D G Y C A+N +G+ A+ Y+ V
Sbjct: 2590 LVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 2622
Score = 55.2 bits (127), Expect = 1e-06
Identities = 50/167 (29%), Positives = 74/167 (44%), Gaps = 13/167 (7%)
Query: 122 GDTVVLECLPPRGSPEPNVYWK-KNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGR 177
G TV L C P +G P P+V W +G + D R+ + G L +Q A D G
Sbjct: 490 GGTVGLNC-PGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGV 548
Query: 178 YQCIARNAAGTRESAIATLKIHI-KPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDV 233
Y CI+ N ++ I T +I + +P + E+ + T G ++ C G P +
Sbjct: 549 YHCISSNYD---DADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDASI 605
Query: 234 LWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
W R KVL++G+LR+ V D+G Y C A N G
Sbjct: 606 SWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSG 652
Score = 53.6 bits (123), Expect = 4e-06
Identities = 51/188 (27%), Positives = 77/188 (40%), Gaps = 15/188 (7%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGG-NMPL----GRVKVLDDGSLRLDNVILADEGEY 270
G +V C GDP P V W + G P GR+ + G L L D G Y
Sbjct: 490 GGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMADSFDTGVY 549
Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVN--VESGNVARFTCTATGRPEPTMFWSV 328
C + N A + +TV +P N ++ V G C +TG P+ ++ W +
Sbjct: 550 HCISSNYDDADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPCHSTGIPDASISWVI 609
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
GN + SRDK V + T+ + T K+ + C A N +G F+ +++
Sbjct: 610 PGNNVLY--QSSRDK----KVLNNGTLRILQVTPKD--QGYYRCVAANPSGVDFLIFQVS 661
Query: 389 VTSDDDRP 396
V RP
Sbjct: 662 VKMKGQRP 669
Score = 50.8 bits (116), Expect = 3e-05
Identities = 46/175 (26%), Positives = 71/175 (40%), Gaps = 11/175 (6%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWY-----KGGVLVVSDTHRSILPAGGLFFLRATH 73
L+ TV LNC G P+P + W K VS+ R ++ G L+
Sbjct: 483 LEHTVLVGGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSEDGRILIDKSGKLELQMAD 542
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDTVVLECLPP 132
D GVY C ++N Y A + V L E ++ G+T+ L C
Sbjct: 543 S---FDTGVYHCISSN-YDDADILTYRITVVEPLVEAYQENGIHHTVFIGETLDLPC-HS 597
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
G P+ ++ W G +L+ +++ G L I D G Y+C+A N +G
Sbjct: 598 TGIPDASISWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSG 652
Score = 49.6 bits (113), Expect = 7e-05
Identities = 43/170 (25%), Positives = 68/170 (40%), Gaps = 9/170 (5%)
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G C G P P + W + + P +S D + D L + D D+
Sbjct: 490 GGTVGLNCPGQGDPTPHVDWLLADGSKVRAPYVSED---GRILIDKSGKLELQMADSFDT 546
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C + NY + + ++TV + NG + T+ I PC + P+
Sbjct: 547 -GVYHCISSNYDDADILTYRITVV--EPLVEAYQENG-IHHTVFIGETLDLPCHSTGIPD 602
Query: 427 PIIAWYFEGE-ALIQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
I+W G L Q+ R + V N+GTL + + D G Y CVA++ G
Sbjct: 603 ASISWVIPGNNVLYQSSRDKKVLNNGTLRILQVTPKDQGYYRCVAANPSG 652
>BC036524-1|AAH36524.1| 772|Homo sapiens DCC protein protein.
Length = 772
Score = 155 bits (376), Expect = 9e-37
Identities = 178/699 (25%), Positives = 278/699 (39%), Gaps = 78/699 (11%)
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-----RQTDAGRYQCIAR-NAAGTRES 191
P + WKK+G L D R + G+L+IQ+ + D G YQC A +G+ S
Sbjct: 4 PVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIIS 63
Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG--RV 249
A + + ++ E V A G +V +C V G+P+P + W+++ G RV
Sbjct: 64 RTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRV 123
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS-GYLTVYDPPSINLS------PNSV 302
VL G+L++ + D G Y C A N + + + + + P ++ P++V
Sbjct: 124 VVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNV 183
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
G A +G P P+ W + G I + KY ++ G +L N TD
Sbjct: 184 VAIEGKDAVLEGCVSGYPPPSFTW-LRGEEVI---QLRSKKY---SLLGGSNLLISNVTD 236
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTA 421
+ T V + N S+ +LTV PP N PSN +SM + F CT
Sbjct: 237 DDSGMYTCVVTYKNENISA--SAELTVLV-----PPWFLNHPSN-LYAYESMDIEFECTV 288
Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P + W G+ +I + + L + + KSD G Y CVA + G S
Sbjct: 289 SGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQ 348
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
L+V P P+ S LP P + V+ V LSW + +I + V
Sbjct: 349 LIVPKPAIPS--------SSVLPSAPRDVVPVLVSSRFVRLSWRPPAE-AKGNIQTFTV- 398
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
FSRE G+N R + + V +L P Y F V N GP
Sbjct: 399 FFSRE---GDNRER-----ALNTTQPGSLQLTVGNLKPEAMYTFRVVAYNEW---GPGES 447
Query: 602 SDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYL 661
S + V G VE ++A +I + WE Y
Sbjct: 448 SQPIKVATQPELQVPGP-----------------VENLQAVSTSPTSILITWE--PPAYA 488
Query: 662 EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNS 721
G +R + + I D +++ L+K+T+Y + + + G ++
Sbjct: 489 NGPVQGYRLFCTEVSTGKEQNI--EVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDD 546
Query: 722 RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKS 781
TL DVP PP N+ + ++N+ ++ + W PP QNG ITGY +
Sbjct: 547 ITVVTLSDVPSAPPQNVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEME 606
Query: 782 MVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
+ N + + T L G YS Q++A T+ G GP
Sbjct: 607 TLEPNNLWY-----LFTGLEKGSQYSFQVSAMTVNGTGP 640
Score = 143 bits (346), Expect = 4e-33
Identities = 123/390 (31%), Positives = 173/390 (44%), Gaps = 34/390 (8%)
Query: 41 PAIRWYKGGVLVV--SDTHRSILPAGGLFFLRATHGRVHS-DAGVYWCEAT-NSYGTARS 96
P I+W K G+ + D + L G L H R H D G+Y CEA+ G+ S
Sbjct: 4 PVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKPDEGLYQCEASLGDSGSIIS 63
Query: 97 RNATLHVA-VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGD 154
R A + VA LR F + ES + GDTV+L+C G P P ++W+KN Q L GD
Sbjct: 64 RTAKVAVAGPLR--FLSQTESVTAFMGDTVLLKC-EVIGEPMPTIHWQKNQQDLTPIPGD 120
Query: 155 SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI------HIKPYLITGP 208
SR+ ++ G L I + D G Y+C ARN A +R A ++I H + Y + P
Sbjct: 121 SRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRP 180
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
+VVA G + V G P P W R + + +L +L + NV D G
Sbjct: 181 SNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSG 240
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
Y+C +SAS LTV PP P+++ F CT +G+P PT+ W
Sbjct: 241 MYTCVVTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMK 300
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
G+ ++ P D + G + L I K+D C A N AG++ +L
Sbjct: 301 NGD--VVIPS---DYFQIV----GGSNLRILGVVKSD-EGFYQCVAENEAGNAQTSAQLI 350
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
V P P I PS+ LP V P
Sbjct: 351 V------PKPAI---PSSSVLPSAPRDVVP 371
Score = 118 bits (283), Expect = 2e-25
Identities = 83/298 (27%), Positives = 134/298 (44%), Gaps = 20/298 (6%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG---VLVVSDTHRSILPAGGLFFLRA 71
+ Q VT L C G P P I W K + D+ +LP+G L R
Sbjct: 77 LSQTESVTAFMGDTVLLKCEVIGEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRL 136
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHV----AVLREEFRLE-PESKQSAQGDTVV 126
G D G+Y C A N + A + + + R+ + L+ P + + +G V
Sbjct: 137 QPG----DIGIYRCSARNPASSRTGNEAEVRILSDPGLHRQLYFLQRPSNVVAIEGKDAV 192
Query: 127 LE-CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
LE C+ G P P+ W + G+ ++ + L+ G NL+I + D+G Y C+
Sbjct: 193 LEGCV--SGYPPPSFTWLR-GEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVV-TY 248
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
SA A L + + P+ + P ++ A + F+C V G P+P V W ++ G +P
Sbjct: 249 KNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKN-GDVVIP 307
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSINLSPNS 301
+++ +LR+ V+ +DEG Y C AEN G S L V P PS ++ P++
Sbjct: 308 SDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSA 365
Score = 69.7 bits (163), Expect = 6e-11
Identities = 59/211 (27%), Positives = 87/211 (41%), Gaps = 14/211 (6%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLRA 71
Y +++P +V + A L G P P+ W +G V+ + S+L L
Sbjct: 175 YFLQRPSNVVAIEGKDAVLEGCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNV 234
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
T D+G+Y C T S +A L V V F P + + + + EC
Sbjct: 235 T----DDDSGMYTCVVTYKNENI-SASAELTVLV-PPWFLNHPSNLYAYESMDIEFEC-T 287
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
G P P V W KNG ++ +V G NL I ++D G YQC+A N AG ++
Sbjct: 288 VSGKPVPTVNWMKNGDVVI--PSDYFQIVGGSNLRILGVVKSDEGFYQCVAENEAGNAQT 345
Query: 192 AIATL----KIHIKPYLITGPEDVVAQTGSS 218
+ + I L + P DVV SS
Sbjct: 346 SAQLIVPKPAIPSSSVLPSAPRDVVPVLVSS 376
Score = 46.0 bits (104), Expect = 8e-04
Identities = 24/85 (28%), Positives = 35/85 (41%), Gaps = 4/85 (4%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P+ + P ++ C G P P + W K G +V+ + I+ L L
Sbjct: 265 PWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVVIPSDYFQIVGGSNLRIL-- 322
Query: 72 THGRVHSDAGVYWCEATNSYGTARS 96
G V SD G Y C A N G A++
Sbjct: 323 --GVVKSDEGFYQCVAENEAGNAQT 345
>AK056336-1|BAB71154.1| 512|Homo sapiens protein ( Homo sapiens
cDNA FLJ31774 fis, clone NT2RI2008050, weakly similar to
BASEMENT MEMBRANE-SPECIFIC HEPARAN SULFATE PROTEOGLYCAN
CORE ).
Length = 512
Score = 148 bits (358), Expect = 1e-34
Identities = 133/478 (27%), Positives = 202/478 (42%), Gaps = 33/478 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EAP ++ ++ VA + C+ G P P ++W+KG + + T I P GL +
Sbjct: 41 EAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLELRPSTFLIIDPLLGLLKI 100
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
+ T DAG Y C A N G A + TL V F EP G V L C
Sbjct: 101 QETQDL---DAGDYTCVAINEAGRATGK-ITLDVGS-PPVFIQEPADVSMEIGSNVTLPC 155
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+G PEP + W++ +F S + + G L I + +D G Y C A N
Sbjct: 156 YV-QGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKGTYICEAENQF 214
Query: 187 GTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLW-RRSAGGGN 243
G +S T+ + P + P G +T C + G+P+P+ W + SA
Sbjct: 215 GKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQ 274
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
P + V DGSL ++ V L D GEY+C A N G + + + V+ P+I ++
Sbjct: 275 NPY--ITVRSDGSLHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVLPTIQHGQQILS 332
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G C A+G P+P++ WS +G S K+ A A DG + +
Sbjct: 333 TIEGIPVTLPCKASGNPKPSVIWSKKGE----LISTSSAKFSAGA--DGSLYVV---SPG 383
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK------SMAVF 417
+ VC+A N AG + + +LTV RP +Q P++
Sbjct: 384 GEESGEYVCTATNTAGYAKRKVQLTVYV---RPRVFGDQRGLSQDKPVEISVLAGEEVTL 440
Query: 418 PCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
PC P PII W E + + + R G++ + + SDSG Y CVA++ G
Sbjct: 441 PCEVKSLPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAG 498
Score = 139 bits (337), Expect = 5e-32
Identities = 126/409 (30%), Positives = 175/409 (42%), Gaps = 38/409 (9%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
DAG+Y C A+NS GT + +N+TL + + + A GD V+EC G P P
Sbjct: 16 DAGIYGCLASNSAGTDK-QNSTLRY-IEAPKLMVVQSELLVALGDITVMEC-KTSGIPPP 72
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
V W K L S ++D G L IQ+ + DAG Y C+A N AG R + TL
Sbjct: 73 QVKWFKGDLEL---RPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAINEAG-RATGKITL 128
Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-------GRV 249
+ P I P DV + GS+VT C V G P P + WRR NMP+ +
Sbjct: 129 DVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRL---DNMPIFSRPFSVSSI 185
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESG 307
L G+L + N+ +D+G Y CEAEN G + + +TV P I +SP+ NV G
Sbjct: 186 SQLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEG 245
Query: 308 NVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
CT G P P W I M + T DG L I D
Sbjct: 246 QQLTLPCTLLAGNPIPERRW-------IKNSAMLLQNPYITVRSDG--SLHIERVQLQDG 296
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N AG++ + V P I +G + PC A P+
Sbjct: 297 -GEYTCVASNVAGTNNKTTSVVV-----HVLPTIQHGQQILSTIEGIPVTLPCKASGNPK 350
Query: 427 PIIAWYFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P + W +GE + + + + DG+L + +SG Y C A++ G
Sbjct: 351 PSVIWSKKGELISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAG 399
Score = 135 bits (327), Expect = 8e-31
Identities = 108/394 (27%), Positives = 163/394 (41%), Gaps = 29/394 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-----SDTHRSILPA 63
G P I++P DV++ TL C G P P I+W + + + S + S L
Sbjct: 131 GSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSISQLRT 190
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G LF L SD G Y CEA N +G +S ++ + P +G
Sbjct: 191 GALFILNLW----ASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQ 246
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
+ L C G+P P W KN LL + + + G+L I+ + D G Y C+A
Sbjct: 247 QLTLPCTLLAGNPIPERRWIKNSAMLL--QNPYITVRSDGSLHIERVQLQDGGEYTCVAS 304
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
N AGT + + +H+ P + G + + G VT C+ G+P P V+W + +
Sbjct: 305 NVAGTNNKTTSVV-VHVLPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWSKKGELIS 363
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-----NLS 298
+ DGSL + + + GEY C A N+ G LTVY P + LS
Sbjct: 364 TSSAKFSAGADGSLYVVSPGGEESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLS 423
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
P ++V +G C P P + W+ E +I P R + +
Sbjct: 424 QDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKE--TQLISPFSPRHTFLPSG------S 475
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
+ I +T +DS +C A N AG+ KL V
Sbjct: 476 MKITETRTSDS-GMYLCVATNIAGNVTQAVKLNV 508
Score = 121 bits (292), Expect = 1e-26
Identities = 104/382 (27%), Positives = 166/382 (43%), Gaps = 23/382 (6%)
Query: 159 LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
+ G L I++A DAG Y C+A N+AGT + +TL+ P L+ +++ G
Sbjct: 1 MTSDGTLFIKNAAPKDAGIYGCLASNSAGT-DKQNSTLRYIEAPKLMVVQSELLVALGDI 59
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAEN 276
+C+ G P P V W + G + ++D G L++ D G+Y+C A N
Sbjct: 60 TVMECKTSGIPPPQVKWFK--GDLELRPSTFLIIDPLLGLLKIQETQDLDAGDYTCVAIN 117
Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII- 335
G + L V PP P V++E G+ C G PEPT+ W N I
Sbjct: 118 EAGRATGKITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFS 177
Query: 336 --FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
F S + A+F +L + +DK T +C A N G ++ + TVT
Sbjct: 178 RPFSVSSISQLRTGALF----ILNLWASDK----GTYICEAENQFGK--IQSETTVTV-T 226
Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAIC-TPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
P+I PS + PCT + P P W L+QN V +DG+L
Sbjct: 227 GLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSL 286
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
++ + D G YTCVAS+ G + +++V + P I + +S++ G P
Sbjct: 287 HIERVQLQDGGEYTCVASNVAGTNNKTTSVVVH--VLPTIQHGQQI-LSTIEGIPVTLPC 343
Query: 513 HNVTDTSVTLSWSQNNKIGSSS 534
+ ++ WS+ ++ S+S
Sbjct: 344 KASGNPKPSVIWSKKGELISTS 365
Score = 93.5 bits (222), Expect = 4e-18
Identities = 77/294 (26%), Positives = 124/294 (42%), Gaps = 18/294 (6%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT AP I P V Q TL C G+P P RW K +++ + + ++ G
Sbjct: 225 VTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDG 284
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L R D G Y C A+N GT ++ ++ V VL + + + +G
Sbjct: 285 SLHIERVQL----QDGGEYTCVASNVAGT-NNKTTSVVVHVL-PTIQHGQQILSTIEGIP 338
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
V L C G+P+P+V W K G+ L+ ++ G+L + ++G Y C A N
Sbjct: 339 VTLPC-KASGNPKPSVIWSKKGE-LISTSSAKFSAGADGSLYVVSPGGEESGEYVCTATN 396
Query: 185 AAGTRESAIATLKIHIKPYLITG--------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
AG + + L ++++P + P ++ G VT C V P P + W
Sbjct: 397 TAGYAKRKVQ-LTVYVRPRVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWA 455
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
+ + R L GS+++ +D G Y C A N G V+ + L V+
Sbjct: 456 KETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVATNIAGNVTQAVKLNVH 509
>BC111748-1|AAI11749.1| 1007|Homo sapiens roundabout homolog 4,
magic roundabout (Drosophila) protein.
Length = 1007
Score = 147 bits (355), Expect = 3e-34
Identities = 86/212 (40%), Positives = 115/212 (54%), Gaps = 14/212 (6%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLFF 68
P I+ P D PA ++C+A G P P IRW G +V D H +LP G L
Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHH-LLPDGTLLL 90
Query: 69 LRA-THGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L+ G H +D GVY CEA+N GTA SR A L VAVLRE+F+++P +
Sbjct: 91 LQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVV 150
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ LEC PP G PEP V W K+G+ L H V GG+L++ A ++D G Y C+
Sbjct: 151 GEQFTLECGPPWGHPEPTVSWWKDGKPLAL--QPGRHTVSGGSLLMARAEKSDEGTYMCV 208
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
A N+AG RES A + I +P T P +++A
Sbjct: 209 ATNSAGHRESRAARVSIQ-EPQDYTEPVELLA 239
Score = 60.9 bits (141), Expect = 3e-08
Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 25/196 (12%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I + P + AR +C A+G+P PT+ W + G + P D +H D
Sbjct: 31 PPQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPP---DPHHLLP--D 85
Query: 352 GVTVLTINDTDKNDSRN---------TIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPI 399
G T+L + + + + C A N G++ RG + V +D + P
Sbjct: 86 G-TLLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQP- 143
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ + C PEP ++W+ +G+ L R+ + G+L++ +
Sbjct: 144 -----RDMVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLALQPGRHTVSGGSLLMARAE 198
Query: 459 KSDSGTYTCVASSRHG 474
KSD GTY CVA++ G
Sbjct: 199 KSDEGTYMCVATNSAG 214
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/134 (34%), Positives = 61/134 (45%), Gaps = 8/134 (5%)
Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
E+ L YEF + P + G SN + + + VP PP + + N T V + W
Sbjct: 309 ELGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGT-VFVSW 367
Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIA 811
PP + NGII GY V W N S+ N T V + T L + G SY VQ+A
Sbjct: 368 VPPPAENHNGIIRGYQV---W--SLGNTSLPPANWTVVGEQTQLEIATHMPG-SYCVQVA 421
Query: 812 AETIIGLGPFSQKV 825
A T G G S+ V
Sbjct: 422 AVTGAGAGEPSRPV 435
Score = 51.2 bits (117), Expect = 2e-05
Identities = 55/214 (25%), Positives = 85/214 (39%), Gaps = 26/214 (12%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKVLDDGSLRL- 259
P ++ P+D + Q C+ G P P + W + +M P +L DG+L L
Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGTLLLL 91
Query: 260 ----------DNVILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVESG 307
+ D G Y+CEA N +G AVS L+V + P + G
Sbjct: 92 QPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVG 151
Query: 308 NVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
C G PEPT+ W +G + PG H + G ++L +K+D
Sbjct: 152 EQFTLECGPPWGHPEPTVSWWKDGKPLALQPGR-----HTVS---GGSLLMAR-AEKSD- 201
Query: 367 RNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
T +C A N AG R ++++ D P+
Sbjct: 202 EGTYMCVATNSAGHRESRAARVSIQEPQDYTEPV 235
Score = 39.5 bits (88), Expect = 0.072
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 14/103 (13%)
Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGT 451
D PP I+ + P +Q A C A P P I W G+ L + ++ DGT
Sbjct: 29 DSPPQILVH-PQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGT 87
Query: 452 LVLKDLD-----------KSDSGTYTCVASSRHGKYVWSGALL 483
L+L +D G YTC AS+R G V GA L
Sbjct: 88 LLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARL 130
>BC111562-1|AAI11563.1| 1007|Homo sapiens roundabout homolog 4,
magic roundabout (Drosophila) protein.
Length = 1007
Score = 147 bits (355), Expect = 3e-34
Identities = 86/212 (40%), Positives = 115/212 (54%), Gaps = 14/212 (6%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLFF 68
P I+ P D PA ++C+A G P P IRW G +V D H +LP G L
Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHH-LLPDGTLLL 90
Query: 69 LRA-THGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L+ G H +D GVY CEA+N GTA SR A L VAVLRE+F+++P +
Sbjct: 91 LQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVV 150
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ LEC PP G PEP V W K+G+ L H V GG+L++ A ++D G Y C+
Sbjct: 151 GEQFTLECGPPWGHPEPTVSWWKDGKPLAL--QPGRHTVSGGSLLMARAEKSDEGTYMCV 208
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
A N+AG RES A + I +P T P +++A
Sbjct: 209 ATNSAGHRESRAARVSIQ-EPQDYTEPVELLA 239
Score = 60.9 bits (141), Expect = 3e-08
Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 25/196 (12%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I + P + AR +C A+G+P PT+ W + G + P D +H D
Sbjct: 31 PPQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPP---DPHHLLP--D 85
Query: 352 GVTVLTINDTDKNDSRN---------TIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPI 399
G T+L + + + + C A N G++ RG + V +D + P
Sbjct: 86 G-TLLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQP- 143
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ + C PEP ++W+ +G+ L R+ + G+L++ +
Sbjct: 144 -----RDMVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLALQPGRHTVSGGSLLMARAE 198
Query: 459 KSDSGTYTCVASSRHG 474
KSD GTY CVA++ G
Sbjct: 199 KSDEGTYMCVATNSAG 214
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/134 (34%), Positives = 61/134 (45%), Gaps = 8/134 (5%)
Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
E+ L YEF + P + G SN + + + VP PP + + N T V + W
Sbjct: 309 ELGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGT-VFVSW 367
Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIA 811
PP + NGII GY V W N S+ N T V + T L + G SY VQ+A
Sbjct: 368 VPPPAENHNGIIRGYQV---W--SLGNTSLPPANWTVVGEQTQLEIATHMPG-SYCVQVA 421
Query: 812 AETIIGLGPFSQKV 825
A T G G S+ V
Sbjct: 422 AVTGAGAGEPSRPV 435
Score = 51.2 bits (117), Expect = 2e-05
Identities = 55/214 (25%), Positives = 85/214 (39%), Gaps = 26/214 (12%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKVLDDGSLRL- 259
P ++ P+D + Q C+ G P P + W + +M P +L DG+L L
Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGTLLLL 91
Query: 260 ----------DNVILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVESG 307
+ D G Y+CEA N +G AVS L+V + P + G
Sbjct: 92 QPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVG 151
Query: 308 NVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
C G PEPT+ W +G + PG H + G ++L +K+D
Sbjct: 152 EQFTLECGPPWGHPEPTVSWWKDGKPLALQPGR-----HTVS---GGSLLMAR-AEKSD- 201
Query: 367 RNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
T +C A N AG R ++++ D P+
Sbjct: 202 EGTYMCVATNSAGHRESRAARVSIQEPQDYTEPV 235
Score = 39.5 bits (88), Expect = 0.072
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 14/103 (13%)
Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGT 451
D PP I+ + P +Q A C A P P I W G+ L + ++ DGT
Sbjct: 29 DSPPQILVH-PQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGT 87
Query: 452 LVLKDLD-----------KSDSGTYTCVASSRHGKYVWSGALL 483
L+L +D G YTC AS+R G V GA L
Sbjct: 88 LLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARL 130
>BC039602-1|AAH39602.1| 1007|Homo sapiens roundabout homolog 4,
magic roundabout (Drosophila) protein.
Length = 1007
Score = 147 bits (355), Expect = 3e-34
Identities = 86/212 (40%), Positives = 115/212 (54%), Gaps = 14/212 (6%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLFF 68
P I+ P D PA ++C+A G P P IRW G +V D H +LP G L
Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHH-LLPDGTLLL 90
Query: 69 LRA-THGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L+ G H +D GVY CEA+N GTA SR A L VAVLRE+F+++P +
Sbjct: 91 LQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVV 150
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ LEC PP G PEP V W K+G+ L H V GG+L++ A ++D G Y C+
Sbjct: 151 GEQFTLECGPPWGHPEPTVSWWKDGKPLAL--QPGRHTVSGGSLLMARAEKSDEGTYMCV 208
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
A N+AG RES A + I +P T P +++A
Sbjct: 209 ATNSAGHRESRAARVSIQ-EPQDYTEPVELLA 239
Score = 60.9 bits (141), Expect = 3e-08
Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 25/196 (12%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I + P + AR +C A+G+P PT+ W + G + P D +H D
Sbjct: 31 PPQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPP---DPHHLLP--D 85
Query: 352 GVTVLTINDTDKNDSRN---------TIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPI 399
G T+L + + + + C A N G++ RG + V +D + P
Sbjct: 86 G-TLLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQP- 143
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ + C PEP ++W+ +G+ L R+ + G+L++ +
Sbjct: 144 -----RDMVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLALQPGRHTVSGGSLLMARAE 198
Query: 459 KSDSGTYTCVASSRHG 474
KSD GTY CVA++ G
Sbjct: 199 KSDEGTYMCVATNSAG 214
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/134 (34%), Positives = 61/134 (45%), Gaps = 8/134 (5%)
Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
E+ L YEF + P + G SN + + + VP PP + + N T V + W
Sbjct: 309 ELGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGT-VFVSW 367
Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIA 811
PP + NGII GY V W N S+ N T V + T L + G SY VQ+A
Sbjct: 368 VPPPAENHNGIIRGYQV---W--SLGNTSLPPANWTVVGEQTQLEIATHMPG-SYCVQVA 421
Query: 812 AETIIGLGPFSQKV 825
A T G G S+ V
Sbjct: 422 AVTGAGAGEPSRPV 435
Score = 51.2 bits (117), Expect = 2e-05
Identities = 55/214 (25%), Positives = 85/214 (39%), Gaps = 26/214 (12%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKVLDDGSLRL- 259
P ++ P+D + Q C+ G P P + W + +M P +L DG+L L
Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGTLLLL 91
Query: 260 ----------DNVILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVESG 307
+ D G Y+CEA N +G AVS L+V + P + G
Sbjct: 92 QPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVG 151
Query: 308 NVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
C G PEPT+ W +G + PG H + G ++L +K+D
Sbjct: 152 EQFTLECGPPWGHPEPTVSWWKDGKPLALQPGR-----HTVS---GGSLLMAR-AEKSD- 201
Query: 367 RNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
T +C A N AG R ++++ D P+
Sbjct: 202 EGTYMCVATNSAGHRESRAARVSIQEPQDYTEPV 235
Score = 39.5 bits (88), Expect = 0.072
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 14/103 (13%)
Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGT 451
D PP I+ + P +Q A C A P P I W G+ L + ++ DGT
Sbjct: 29 DSPPQILVH-PQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGT 87
Query: 452 LVLKDLD-----------KSDSGTYTCVASSRHGKYVWSGALL 483
L+L +D G YTC AS+R G V GA L
Sbjct: 88 LLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARL 130
>AY358083-1|AAQ88450.1| 1004|Homo sapiens magic roundabout protein.
Length = 1004
Score = 147 bits (355), Expect = 3e-34
Identities = 86/212 (40%), Positives = 115/212 (54%), Gaps = 14/212 (6%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLFF 68
P I+ P D PA ++C+A G P P IRW G +V D H +LP G L
Sbjct: 29 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHH-LLPDGTLLL 87
Query: 69 LRA-THGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L+ G H +D GVY CEA+N GTA SR A L VAVLRE+F+++P +
Sbjct: 88 LQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVV 147
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ LEC PP G PEP V W K+G+ L H V GG+L++ A ++D G Y C+
Sbjct: 148 GEQFTLECGPPWGHPEPTVSWWKDGKPLAL--QPGRHTVSGGSLLMARAEKSDEGTYMCV 205
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
A N+AG RES A + I +P T P +++A
Sbjct: 206 ATNSAGHRESRAARVSIQ-EPQDYTEPVELLA 236
Score = 60.9 bits (141), Expect = 3e-08
Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 25/196 (12%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I + P + AR +C A+G+P PT+ W + G + P D +H D
Sbjct: 28 PPQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPP---DPHHLLP--D 82
Query: 352 GVTVLTINDTDKNDSRN---------TIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPI 399
G T+L + + + + C A N G++ RG + V +D + P
Sbjct: 83 G-TLLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQP- 140
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ + C PEP ++W+ +G+ L R+ + G+L++ +
Sbjct: 141 -----RDMVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLALQPGRHTVSGGSLLMARAE 195
Query: 459 KSDSGTYTCVASSRHG 474
KSD GTY CVA++ G
Sbjct: 196 KSDEGTYMCVATNSAG 211
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/134 (34%), Positives = 61/134 (45%), Gaps = 8/134 (5%)
Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
E+ L YEF + P + G SN + + + VP PP + + N T V + W
Sbjct: 306 ELGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGT-VFVSW 364
Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIA 811
PP + NGII GY V W N S+ N T V + T L + G SY VQ+A
Sbjct: 365 VPPPAENHNGIIRGYQV---W--SLGNTSLPPANWTVVGEQTQLEIATHMPG-SYCVQVA 418
Query: 812 AETIIGLGPFSQKV 825
A T G G S+ V
Sbjct: 419 AVTGAGAGEPSRPV 432
Score = 51.2 bits (117), Expect = 2e-05
Identities = 55/214 (25%), Positives = 85/214 (39%), Gaps = 26/214 (12%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKVLDDGSLRL- 259
P ++ P+D + Q C+ G P P + W + +M P +L DG+L L
Sbjct: 29 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGTLLLL 88
Query: 260 ----------DNVILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVESG 307
+ D G Y+CEA N +G AVS L+V + P + G
Sbjct: 89 QPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVG 148
Query: 308 NVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
C G PEPT+ W +G + PG H + G ++L +K+D
Sbjct: 149 EQFTLECGPPWGHPEPTVSWWKDGKPLALQPGR-----HTVS---GGSLLMAR-AEKSD- 198
Query: 367 RNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
T +C A N AG R ++++ D P+
Sbjct: 199 EGTYMCVATNSAGHRESRAARVSIQEPQDYTEPV 232
Score = 39.5 bits (88), Expect = 0.072
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 14/103 (13%)
Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGT 451
D PP I+ + P +Q A C A P P I W G+ L + ++ DGT
Sbjct: 26 DSPPQILVH-PQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGT 84
Query: 452 LVLKDLD-----------KSDSGTYTCVASSRHGKYVWSGALL 483
L+L +D G YTC AS+R G V GA L
Sbjct: 85 LLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARL 127
>AF361473-1|AAL31867.1| 1007|Homo sapiens magic roundabout protein.
Length = 1007
Score = 147 bits (355), Expect = 3e-34
Identities = 86/212 (40%), Positives = 115/212 (54%), Gaps = 14/212 (6%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLFF 68
P I+ P D PA ++C+A G P P IRW G +V D H +LP G L
Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHH-LLPDGTLLL 90
Query: 69 LRA-THGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L+ G H +D GVY CEA+N GTA SR A L VAVLRE+F+++P +
Sbjct: 91 LQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVV 150
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ LEC PP G PEP V W K+G+ L H V GG+L++ A ++D G Y C+
Sbjct: 151 GEQFTLECGPPWGHPEPTVSWWKDGKPLAL--QPGRHTVSGGSLLMARAEKSDEGTYMCV 208
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
A N+AG RES A + I +P T P +++A
Sbjct: 209 ATNSAGHRESRAARVSIQ-EPQDYTEPVELLA 239
Score = 60.9 bits (141), Expect = 3e-08
Identities = 50/196 (25%), Positives = 84/196 (42%), Gaps = 25/196 (12%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I + P + AR +C A+G+P PT+ W + G + P D +H D
Sbjct: 31 PPQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPP---DPHHLLP--D 85
Query: 352 GVTVLTINDTDKNDSRN---------TIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPI 399
G T+L + + + + C A N G++ RG + V +D + P
Sbjct: 86 G-TLLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQP- 143
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ + C PEP ++W+ +G+ L R+ + G+L++ +
Sbjct: 144 -----RDMVAVVGEQFTLECGPPWGHPEPTVSWWKDGKPLALQPGRHTVSGGSLLMARAE 198
Query: 459 KSDSGTYTCVASSRHG 474
KSD GTY CVA++ G
Sbjct: 199 KSDEGTYMCVATNSAG 214
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/134 (34%), Positives = 61/134 (45%), Gaps = 8/134 (5%)
Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
E+ L YEF + P + G SN + + + VP PP + + N T V + W
Sbjct: 309 ELGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGT-VFVSW 367
Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIA 811
PP + NGII GY V W N S+ N T V + T L + G SY VQ+A
Sbjct: 368 VPPPAENHNGIIRGYQV---W--SLGNTSLPPANWTVVGEQTQLEIATHMPG-SYCVQVA 421
Query: 812 AETIIGLGPFSQKV 825
A T G G S+ V
Sbjct: 422 AVTGAGAGEPSRPV 435
Score = 51.2 bits (117), Expect = 2e-05
Identities = 55/214 (25%), Positives = 85/214 (39%), Gaps = 26/214 (12%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKVLDDGSLRL- 259
P ++ P+D + Q C+ G P P + W + +M P +L DG+L L
Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGTLLLL 91
Query: 260 ----------DNVILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVESG 307
+ D G Y+CEA N +G AVS L+V + P + G
Sbjct: 92 QPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVG 151
Query: 308 NVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
C G PEPT+ W +G + PG H + G ++L +K+D
Sbjct: 152 EQFTLECGPPWGHPEPTVSWWKDGKPLALQPGR-----HTVS---GGSLLMAR-AEKSD- 201
Query: 367 RNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
T +C A N AG R ++++ D P+
Sbjct: 202 EGTYMCVATNSAGHRESRAARVSIQEPQDYTEPV 235
Score = 39.5 bits (88), Expect = 0.072
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 14/103 (13%)
Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGT 451
D PP I+ + P +Q A C A P P I W G+ L + ++ DGT
Sbjct: 29 DSPPQILVH-PQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGT 87
Query: 452 LVLKDLD-----------KSDSGTYTCVASSRHGKYVWSGALL 483
L+L +D G YTC AS+R G V GA L
Sbjct: 88 LLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARL 130
>AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein.
Length = 2828
Score = 147 bits (355), Expect = 3e-34
Identities = 136/499 (27%), Positives = 208/499 (41%), Gaps = 48/499 (9%)
Query: 9 GEAPYII-EQPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTH--RSILPA 63
GE P I+ + P V+V C A G P P + W K G L+ +T R +
Sbjct: 1850 GEKPQILTKSPQTVSVTAETDTVFPCEATGKPKPFVTWTKVSTGALMTPNTRIQRFEVLK 1909
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-G 122
G +R + D G Y C A+N +G R L V V + + + G
Sbjct: 1910 NGTLVIRKVQVQ---DRGQYMCTASNLHGLDRMV-VLLSVTVQQPQILASHYQDVTVYLG 1965
Query: 123 DTVVLECLPPRGSPEPNVYW----KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
DT+ +ECL +G+P P + W ++ QT+ +SR+ L + L I++A +D G Y
Sbjct: 1966 DTIAMECLA-KGTPAPQISWIFPDRRVWQTVS-PVESRITLHENRTLSIKEASFSDRGVY 2023
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+C+A NAAG AI + P + E++ G S+ C PLP V W
Sbjct: 2024 KCVASNAAGADSLAIRLHVAALPPVIHQEKLENISLPPGLSIHIHCTAKAAPLPSVRWVL 2083
Query: 238 SAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G P G + V +G+L + N+ D G Y C A N VG+ + L V
Sbjct: 2084 GDGTQIRPSQFLHGNLFVFPNGTLYIRNLAPKDSGRYECVAANLVGSARRTVQLNVQRAA 2143
Query: 294 S----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI--IFPGMSRDKYHAT 347
+ SP +V G + C+A+G P P + W + R I +F SR K A
Sbjct: 2144 ANARITGTSPRRTDVRYGGTLKLDCSASGDPWPRILWRLPSKRMIDALFSFDSRIKVFAN 2203
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
+ V ++ D D D +C A N G +V K+ V +P I ++
Sbjct: 2204 GT---LVVKSVTDKDAGD----YLCVARNKVGDDYVVLKVDVVM---KPAKIEHKEENDH 2253
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN-----------VTNDGTLVLKD 456
+ C A P P I+W +L+ + ++ V N+GTL +
Sbjct: 2254 KVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNE 2313
Query: 457 LDKSDSGTYTCVASSRHGK 475
+ + G YTC A ++ GK
Sbjct: 2314 VGMREEGDYTCFAENQVGK 2332
Score = 138 bits (334), Expect = 1e-31
Identities = 136/480 (28%), Positives = 206/480 (42%), Gaps = 55/480 (11%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDT---HRS--ILPAGGLFFLRATHGRVHSDAGVYWC 85
++C A +P P++RW G + + H + + P G L+ D+G Y C
Sbjct: 2067 IHCTAKAAPLPSVRWVLGDGTQIRPSQFLHGNLFVFPNGTLYI----RNLAPKDSGRYEC 2122
Query: 86 EATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
A N G+AR R L+V R+ P G T+ L+C G P P + W
Sbjct: 2123 VAANLVGSAR-RTVQLNVQRAAANARITGTSPRRTDVRYGGTLKLDC-SASGDPWPRILW 2180
Query: 143 KKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
+ + + LF DSR+ + G LV++ DAG Y C+ARN G + + + +
Sbjct: 2181 RLPSKRMIDALFSFDSRIKVFANGTLVVKSVTDKDAGDYLCVARNKVGD-DYVVLKVDVV 2239
Query: 200 IKPYLITGPE--DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-------GNMPLGRVK 250
+KP I E D G + C G P P++ W G + GR K
Sbjct: 2240 MKPAKIEHKEENDHKVFYGGDLKVDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTK 2299
Query: 251 ---VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVE 305
V ++G+L + V + +EG+Y+C AEN VG + V P+ N + +V V
Sbjct: 2300 RYVVFNNGTLYFNEVGMREEGDYTCFAENQVGKDEMRVRVKVVTAPATIRNKTYLAVQVP 2359
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G+V C A G P P + W N+ I S +KY ++ T+L I ++D
Sbjct: 2360 YGDVVTVACEAKGEPMPKVTWLSPTNKVI---PTSSEKYQ---IYQDGTLL-IQKAQRSD 2412
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA------VFPC 419
S N C N AG + TV + PP I NG N ++ +A + C
Sbjct: 2413 SGN-YTCLVRNSAGED----RKTVWIHVNVQPPKI-NGNPNPITTVREIAAGGSRKLIDC 2466
Query: 420 TAICTPEPIIAWYF-EGEAL---IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P + W F EG L +R V +G+L ++ L KSDS C+A + G+
Sbjct: 2467 KAEGIPTPRVLWAFPEGVVLPAPYYGNRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGE 2526
Score = 109 bits (263), Expect = 4e-23
Identities = 127/489 (25%), Positives = 206/489 (42%), Gaps = 58/489 (11%)
Query: 31 LNCRAGGSPSPAIRW-YKGGVLVVS---------DTHRSILPAGGLFFLRATHGRVHSDA 80
++C A G P+P I W G LV S T R ++ G + R D
Sbjct: 2263 VDCVATGLPNPEISWSLPDGSLVNSFMQSDDSGGRTKRYVVFNNGTLYFNEVGMREEGD- 2321
Query: 81 GVYWCEATNSYGTARSRNATLHV---AVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
Y C A N G R V A +R + L + Q GD V + C +G P
Sbjct: 2322 --YTCFAENQVGKDEMRVRVKVVTAPATIRNKTYL---AVQVPYGDVVTVAC-EAKGEPM 2375
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P V W ++ + + G L+IQ A+++D+G Y C+ RN+AG + +
Sbjct: 2376 PKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQRSDSGNYTCLVRNSAGEDRKTV-WIH 2434
Query: 198 IHIKPYLITG-PEDV-----VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----G 247
++++P I G P + +A GS C+ G P P VLW G +P
Sbjct: 2435 VNVQPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLW-AFPEGVVLPAPYYGN 2493
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--PSINLSPNS--VN 303
R+ V +GSL + ++ +D + C A N G LTV +P I P S +
Sbjct: 2494 RITVHGNGSLDIRSLRKSDSVQLVCMARNEGGEARLIVQLTVLEPMEKPIFHDPISEKIT 2553
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
+G+ C+A G P P++ W V N T + G +++ A DG +L I+
Sbjct: 2554 AMAGHTISLNCSAAGTPTPSLVW-VLPNGTDLQSGQQLQRFYHKA--DG--MLHISGLSS 2608
Query: 364 NDSRNTIVCSAVNYAGSS--FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
D+ C A N AG + V K+ + + ++ + + + +TL + PCT
Sbjct: 2609 VDA-GAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNLVSIINGETLKL------PCTP 2661
Query: 422 ICTPEPIIAW------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ +W + EG + R ++ ++GTL +++ D GTY C + +G
Sbjct: 2662 PGAGQGRFSWTLPNGMHLEGPQTL--GRVSLLDNGTLTVREASVFDRGTYVCRMETEYGP 2719
Query: 476 YVWSGALLV 484
V S ++V
Sbjct: 2720 SVTSIPVIV 2728
Score = 104 bits (249), Expect = 2e-21
Identities = 102/387 (26%), Positives = 164/387 (42%), Gaps = 22/387 (5%)
Query: 10 EAPYIIEQPLDVTVARHQPA-----TLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPA 63
+ P I P +T R A ++C+A G P+P + W + GV++ + + + +
Sbjct: 2438 QPPKINGNPNPITTVREIAAGGSRKLIDCKAEGIPTPRVLWAFPEGVVLPAPYYGNRITV 2497
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQ 121
G L R SD+ C A N G AR + + + +P S++ +
Sbjct: 2498 HGNGSLDIRSLR-KSDSVQLVCMARNEGGEARLIVQLTVLEPMEKPIFHDPISEKITAMA 2556
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS--RMHLVDGGNLVIQDARQTDAGRYQ 179
G T+ L C G+P P++ W T L G R + G L I DAG Y+
Sbjct: 2557 GHTISLNC-SAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHISGLSSVDAGAYR 2615
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ-TGSSVTFQCRVGGDPLPDVLWRRS 238
C+ARNAAG E ++ LK+ +KP ++V+ G ++ C G W
Sbjct: 2616 CVARNAAGHTERLVS-LKVGLKPEANKQYHNLVSIINGETLKLPCTPPGAGQGRFSWTLP 2674
Query: 239 AG---GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPS 294
G G LGRV +LD+G+L + + D G Y C E G +V++ + + PP
Sbjct: 2675 NGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPVIVIAYPPR 2734
Query: 295 INLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
I P V GN + C A G P+ + W + +++ + G+ + + +
Sbjct: 2735 ITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELP-DKSHLKAGV-QARLYGNRFLHPQ 2792
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGS 380
LTI + D+ C A N GS
Sbjct: 2793 GSLTIQHATQRDA-GFYKCMAKNILGS 2818
Score = 103 bits (247), Expect = 4e-21
Identities = 118/475 (24%), Positives = 184/475 (38%), Gaps = 36/475 (7%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRSILPAGGLFFLRATHGRV 76
L V V T+ C A G P P + W V+ S I G L +A
Sbjct: 2354 LAVQVPYGDVVTVACEAKGEPMPKVTWLSPTNKVIPTSSEKYQIYQDGTLLIQKAQ---- 2409
Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-----SKQSAQGDTVVLECLP 131
SD+G Y C NS G R + +HV V + P + +A G +++C
Sbjct: 2410 RSDSGNYTCLVRNSAGEDR-KTVWIHVNVQPPKINGNPNPITTVREIAAGGSRKLIDC-K 2467
Query: 132 PRGSPEPNVYWKKNGQTLL---FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
G P P V W +L + G +R+ + G+L I+ R++D+ + C+ARN G
Sbjct: 2468 AEGIPTPRVLWAFPEGVVLPAPYYG-NRITVHGNGSLDIRSLRKSDSVQLVCMARNEGGE 2526
Query: 189 RESAI-ATLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242
+ T+ ++ + P E + A G +++ C G P P ++W G
Sbjct: 2527 ARLIVQLTVLEPMEKPIFHDPISEKITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQS 2586
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS-PNS 301
L R DG L + + D G Y C A N+ G L V P N N
Sbjct: 2587 GQQLQRFYHKADGMLHISGLSSVDAGAYRCVARNAAGHTERLVSLKVGLKPEANKQYHNL 2646
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
V++ +G + CT G + W++ + P ++ D T LT+ +
Sbjct: 2647 VSIINGETLKLPCTPPGAGQGRFSWTLPNGMHLEGP----QTLGRVSLLDNGT-LTVREA 2701
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR----PPPIITNGPSNQTLPIKSMAV- 416
D R T VC G S + V + R P P+I P N T+ + MA+
Sbjct: 2702 SVFD-RGTYVCRMETEYGPSVTSIPVIVIAYPPRITSEPTPVIYTRPGN-TVKLNCMAMG 2759
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P I P + G R + G+L ++ + D+G Y C+A +
Sbjct: 2760 IPKADITWELPDKSHLKAGVQARLYGNRFLHPQGSLTIQHATQRDAGFYKCMAKN 2814
Score = 89.4 bits (212), Expect = 7e-17
Identities = 77/282 (27%), Positives = 118/282 (41%), Gaps = 17/282 (6%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWY-KGGVLVVS--DTHRSILPAGGLFFLRATHGRVH 77
+T +LNC A G+P+P++ W G + S R A G+ + G
Sbjct: 2552 ITAMAGHTISLNCSAAGTPTPSLVWVLPNGTDLQSGQQLQRFYHKADGMLHIS---GLSS 2608
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG Y C A N+ G R +L V + E + G+T+ L C PP G+ +
Sbjct: 2609 VDAGAYRCVARNAAGHTE-RLVSLKVGLKPEANKQYHNLVSIINGETLKLPCTPP-GAGQ 2666
Query: 138 PNVYWK-KNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
W NG L R+ L+D G L +++A D G Y C G ++I
Sbjct: 2667 GRFSWTLPNGMHLEGPQTLGRVSLLDNGTLTVREASVFDRGTYVCRMETEYGPSVTSIPV 2726
Query: 196 LKIHIKPYLITGPEDVV-AQTGSSVTFQCRVGGDPLPDVLW------RRSAGGGNMPLGR 248
+ I P + + P V+ + G++V C G P D+ W AG G
Sbjct: 2727 IVIAYPPRITSEPTPVIYTRPGNTVKLNCMAMGIPKADITWELPDKSHLKAGVQARLYGN 2786
Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
+ GSL + + D G Y C A+N +G+ S + Y+ V+
Sbjct: 2787 RFLHPQGSLTIQHATQRDAGFYKCMAKNILGSDSKTTYIHVF 2828
Score = 53.2 bits (122), Expect = 5e-06
Identities = 51/208 (24%), Positives = 84/208 (40%), Gaps = 13/208 (6%)
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
Y+ + + + T +R A V+ E + +G L C + S P+++W
Sbjct: 455 YYTQYSQTISTKDTRQARGRSWVMIEPSGAVQRDQTVLEGGPCQLSC-NVKASESPSIFW 513
Query: 143 K-KNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
+G L + D DS+ ++ G L I+ +D+G YQCIA+ + + + +
Sbjct: 514 VLPDGSILKAPMDDPDSKFSILSSGWLRIKSMEPSDSGLYQCIAQ-VRDEMDRMVYRVLV 572
Query: 199 HIKPYLITGPEDVVA---QTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVL 252
P +D V G SVT C P + W R V +L
Sbjct: 573 Q-SPSTQPAEKDTVTIGKNPGESVTLPCNALAIPEAHLSWILPNRRIINDLANTSHVYML 631
Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGA 280
+G+L + V ++D G Y C A N GA
Sbjct: 632 PNGTLSIPKVQVSDSGYYRCVAVNQQGA 659
Score = 48.4 bits (110), Expect = 2e-04
Identities = 49/181 (27%), Positives = 76/181 (41%), Gaps = 23/181 (12%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWY--KGGVLVV----SDTHRSILPAGGLFFLRATH 73
D TV P L+C S SP+I W G +L D+ SIL +G L
Sbjct: 488 DQTVLEGGPCQLSCNVKASESPSIFWVLPDGSILKAPMDDPDSKFSILSSGWL----RIK 543
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-----QGDTVVLE 128
SD+G+Y C A R + VL + +P K + G++V L
Sbjct: 544 SMEPSDSGLYQCIA-----QVRDEMDRMVYRVLVQSPSTQPAEKDTVTIGKNPGESVTLP 598
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFD--GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
C PE ++ W + ++ D S ++++ G L I + +D+G Y+C+A N
Sbjct: 599 C-NALAIPEAHLSWILPNRRIINDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQQ 657
Query: 187 G 187
G
Sbjct: 658 G 658
Score = 38.7 bits (86), Expect = 0.13
Identities = 21/62 (33%), Positives = 32/62 (51%), Gaps = 6/62 (9%)
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTN-----DGTLVLKDLDKSDSGTYTCVASSR 472
PC A+ PE ++W +I N N ++ +GTL + + SDSG Y CVA ++
Sbjct: 598 PCNALAIPEAHLSWILPNRRII-NDLANTSHVYMLPNGTLSIPKVQVSDSGYYRCVAVNQ 656
Query: 473 HG 474
G
Sbjct: 657 QG 658
>U40271-1|AAC50484.2| 1070|Homo sapiens transmembrane receptor
precursor protein.
Length = 1070
Score = 146 bits (354), Expect = 4e-34
Identities = 127/486 (26%), Positives = 209/486 (43%), Gaps = 37/486 (7%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
++ P DV VAR++ A +C+ P P+++W +++ R+ + A G
Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
L R +AG+Y C G ATLH+A + + EP + + V
Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG
Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
R + + + P + P+D + G C P P V+W R+ +
Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VES 306
R +V +G+LR+++V + D Y C + G++ A + V + P +E
Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
A C+ATGR +PT+ W G S ++ V D L ++D+
Sbjct: 517 DKEATVPCSATGREKPTIKWERAD-------GSSLPEW----VTDNAGTLHFARVTRDDA 565
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
N ++ G +LTV P T+ A+ C A P+
Sbjct: 566 GNYTCIASNGPQGQIRAHVQLTVAVFIT-----FKVEPERTTVYQGHTALLQCEAQGDPK 620
Query: 427 PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVA-SSRHGKYVWSGAL 482
P+I W + L R ++ +G+LV+ D+ DSG YTC+A +S + K+ +
Sbjct: 621 PLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLY 680
Query: 483 LVDSPI 488
+VD P+
Sbjct: 681 VVDKPV 686
Score = 112 bits (270), Expect = 6e-24
Identities = 106/373 (28%), Positives = 155/373 (41%), Gaps = 28/373 (7%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P P++ W GV + TH + G L SDAGVY C A N G R
Sbjct: 348 GLPEPSVWWEHAGVRL--PTHGRVYQKGHELVLANI---AESDAGVYTCHAANLAGQRR- 401
Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156
++ + VA + + +P+ Q +G L+CL + +P+P V W +N +L DSR
Sbjct: 402 QDVNITVATVPSWLK-KPQDSQLEEGKPGYLDCLT-QATPKPTVVWYRN--QMLISEDSR 457
Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE-DVVAQT 215
+ G L I D Y+C++ AG+ E A A +++ K P+ +
Sbjct: 458 FEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIE-AQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEA 274
T C G P + W R A G ++P V D+ G+L V D G Y+C A
Sbjct: 517 DKEATVPCSATGREKPTIKWER-ADGSSLPEW---VTDNAGTLHFARVTRDDAGNYTCIA 572
Query: 275 ENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
N G + A LTV + + P V G+ A C A G P+P + W +G
Sbjct: 573 SNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW--KGKDR 630
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
I+ P + H +F + L I+D DS C A N L V
Sbjct: 631 ILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCIAGNSCNIKHTEAPLYVV--- 682
Query: 394 DRPPPIITNGPSN 406
D+P P + GP +
Sbjct: 683 DKPVPEESEGPGS 695
Score = 108 bits (260), Expect = 1e-22
Identities = 127/474 (26%), Positives = 191/474 (40%), Gaps = 41/474 (8%)
Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69
P +++ P + + TL C G P P +W++ G L ++ ++ L
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187
Query: 70 RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125
R G HS G+Y C A +++G A S+N TL +A E F L P+ A+ +
Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180
+ C P P++ W +T + + HL G+L++ R +AG Y+C
Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
I + G ATL + I+ + P A + VT G P P V W +
Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359
Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
G +P GRV L L N+ +D G Y+C A N G +TV PS
Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P +E G C P+PT+ W N+ +I S D VF T L I
Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW--YRNQMLI----SEDS--RFEVFKNGT-LRI 468
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N + D C + AGS + ++ V PP Q + A P
Sbjct: 469 NSVEVYDG-TWYRCMSSTPAGSIEAQARVQVLEKLKFTPP----PQPQQCMEFDKEATVP 523
Query: 419 CTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
C+A +P I W +G +L + N GTL + + D+G YTC+AS+
Sbjct: 524 CSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTCIASN 574
Score = 101 bits (243), Expect = 1e-20
Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+QP + + A L C +P P + W G V DT R L F A
Sbjct: 35 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 90
Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128
R+ D+G + C A + ARS NA+ ++ + P S+ Q T V L
Sbjct: 91 DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
C G P P W ++G T L DG S H V NL ++ A +G Y C A +A
Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
G S TL I + + ++ P+DVV F C+ P P + W
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266
Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296
+ P L R V +GSL L V + G Y C + G + L + + +
Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
L V +G+ R TC G PEP+++W G R P R V+
Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L + + ++D+ C A N AG +TV + P P + L
Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G
Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488
Score = 92.3 bits (219), Expect = 1e-17
Identities = 78/296 (26%), Positives = 119/296 (40%), Gaps = 18/296 (6%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +T P +++P D + +P L+C +P P + WY+ +L+ D+ +
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ 121
G L R V+ D Y C ++ G S A V VL + +F P+ +Q +
Sbjct: 463 NGTL---RINSVEVY-DGTWYRCMSSTPAG---SIEAQARVQVLEKLKFTPPPQPQQCME 515
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQ 179
D G +P + W++ DG S V + G L + DAG Y
Sbjct: 516 FDKEATVPCSATGREKPTIKWERA------DGSSLPEWVTDNAGTLHFARVTRDDAGNYT 569
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RS 238
CIA N + A L + + PE G + QC GDP P + W+ +
Sbjct: 570 CIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKD 629
Query: 239 AGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
LG R+ + +GSL + +V D G Y+C A NS L V D P
Sbjct: 630 RILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685
Score = 83.0 bits (196), Expect = 6e-15
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +P S+ + QG +L C P +VYW +G + D+ G +L
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89
Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222
R D+G +QC+AR+ E+ A +IK P ++ P + Q + VT +
Sbjct: 90 VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280
C + G P P W R + V + +L L G YSC A ++ G A
Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209
Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
S+ + L++ D + L+P V V A F C + +P P++ W E I
Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396
AT +G +LT + + C G + L + +D P
Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451
P + T G + LP K + PEP + W G L H R
Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375
Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
LVL ++ +SD+G YTC A++ G+
Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399
>BC104918-1|AAI04919.1| 1208|Homo sapiens CHL1 protein protein.
Length = 1208
Score = 146 bits (354), Expect = 4e-34
Identities = 120/485 (24%), Positives = 200/485 (41%), Gaps = 34/485 (7%)
Query: 10 EAPYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P II+Q + V + + C A G+P P W K G HR I F
Sbjct: 33 QVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTF 92
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
G + G Y C A+N G A S V + + + + + + +GD +VL
Sbjct: 93 RIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLP 152
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIARNAAG 187
C PP+G P ++YW N + + D R+++ G+L + + D+ Y C A
Sbjct: 153 CNPPKGLPPLHIYWM-NIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRL 211
Query: 188 TRESAIATLKIHI---------KPYLITGPEDVVAQT------GSSVTFQCRVGGDPLPD 232
+K+ + KP L+ P + +++ G + +C G P P
Sbjct: 212 RTIVQKMPMKLTVNSSNSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQ 271
Query: 233 VLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
V W + GG++P GR + G +L+++NV D+G Y C A N +G + ++ V +
Sbjct: 272 VDWNKI--GGDLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEE 329
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP P S +G+ C A G P+PT+ W V G+ P + VF
Sbjct: 330 PPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHP------FAGDVVFP 383
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
++ + N + C A N G+ + V D P I T N +
Sbjct: 384 --REISFTNLQPNHTA-VYQCEASNVHGTILANANIDVV---DVRPLIQTKDGENYATVV 437
Query: 412 KSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
A C +PE +++W E ++ R ++ +GTL + + D+G+Y+C
Sbjct: 438 GYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVE 497
Query: 471 SRHGK 475
+ GK
Sbjct: 498 NAIGK 502
Score = 99 bits (238), Expect = 5e-20
Identities = 167/723 (23%), Positives = 264/723 (36%), Gaps = 83/723 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+G+ ++LEC G P P V W K G L +++ + G L I++ D G Y+C
Sbjct: 254 KGEILLLECFA-EGLPTPQVDWNKIGGDLPKGREAKENY--GKTLKIENVSYQDKGNYRC 310
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
A N GT + + P P+ V TGS+ C G+P P + WR +
Sbjct: 311 TASNFLGTATHDFHVI-VEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGS 369
Query: 241 G-GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
N P V+ + N+ Y CEA N G + A+ + V D + +
Sbjct: 370 PVDNHPFAG-DVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQTK 428
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
+ N + G A C PE + W + P R +YH +++ T L
Sbjct: 429 DGENYATVVGYSAFLHCEFFASPEAVVSWQKVEE---VKPLEGR-RYH---IYENGT-LQ 480
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
IN T + D+ + C N G + V L D R + P N +P M
Sbjct: 481 INRTTEEDA-GSYSCWVENAIGKTAVTANL-----DIRNATKLRVSPKNPRIPKLHMLEL 534
Query: 418 PCTAICTPEPI----IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C + C ++W +GEA N T DG +++ + + S V
Sbjct: 535 HCESKCDSHLKHSLKLSWSKDGEAF----EINGTEDGRIIIDGANLTISN----VTLEDQ 586
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533
G Y S +DS + V +P PP + SV L+W +S
Sbjct: 587 GIYCCSAHTALDSAAD-----ITQVTVLDVPDPPENLHLSERQNRSVRLTWEAGAD-HNS 640
Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSH 593
+I Y VE + G W + R + V+ L P + Y F V N
Sbjct: 641 NISEYIVEFEGNKEEPGR--------WEELTRVQGKKTTVILPLAPFVRYQFRVIAVNEV 692
Query: 594 GLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW 653
G S PS SD T + NI ++A+ IK W
Sbjct: 693 GRSQPSQPSDH-----------HETPPAAPDRNPQNIR-------VQASQPKEMIIK--W 732
Query: 654 EILNFYYLEGLFIYFRPL---DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPF 710
E L G + +R +E+E +T+ + + + Y Y+ +
Sbjct: 733 EPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHT----LRVMTPAVYAPYDVKVQAI 788
Query: 711 YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVV 770
+ G S + +D PD P+ + ++N+T V + WS +G + GY
Sbjct: 789 NQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQ-- 846
Query: 771 VNW------LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824
+NW LD + V I Q S ++ +L + + + + A G GP S+
Sbjct: 847 INWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEP 906
Query: 825 VYF 827
F
Sbjct: 907 YIF 909
Score = 84.2 bits (199), Expect = 3e-15
Identities = 83/301 (27%), Positives = 124/301 (41%), Gaps = 20/301 (6%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +V E P ++P + L C A G P P I+W G V D H
Sbjct: 322 DFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPV--DNHPF--- 376
Query: 63 AGGLFFLR--ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQS 119
AG + F R + + VY CEA+N +GT + NA + V +R + + E+ +
Sbjct: 377 AGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILA-NANIDVVDVRPLIQTKDGENYAT 435
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
G + L C SPE V W+K + +G R H+ + G L I + DAG Y
Sbjct: 436 VVGYSAFLHC-EFFASPEAVVSWQKVEEVKPLEG-RRYHIYENGTLQINRTTEEDAGSYS 493
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVL---W 235
C NA G + + A L I L P++ + C D L L W
Sbjct: 494 CWVENAIG-KTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLSW 552
Query: 236 RRSAGG---GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ GR+ ++D +L + NV L D+G Y C A ++ + + +TV D
Sbjct: 553 SKDGEAFEINGTEDGRI-IIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDV 611
Query: 293 P 293
P
Sbjct: 612 P 612
Score = 82.6 bits (195), Expect = 8e-15
Identities = 69/299 (23%), Positives = 119/299 (39%), Gaps = 17/299 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+T+ + + L C A G P+P + W K G D + + D
Sbjct: 250 ITILKGEILLLECFAEGLPTPQVDWNKIG----GDLPKGREAKENYGKTLKIENVSYQDK 305
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
G Y C A+N GTA HV V + +P+S + G +L C G P+P
Sbjct: 306 GNYRCTASNFLGTATH---DFHVIVEEPPRWTKKPQSAVYSTGSNGILLC-EAEGEPQPT 361
Query: 140 VYWKKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
+ W+ NG + F GD +V + + + YQC A N GT +
Sbjct: 362 IKWRVNGSPVDNHPFAGD----VVFPREISFTNLQPNHTAVYQCEASNVHGTILANANID 417
Query: 197 KIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
+ ++P + T E+ G S C P V W++ + R + ++G
Sbjct: 418 VVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENG 477
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
+L+++ D G YSC EN++G + + L + + + +SP + + ++ C
Sbjct: 478 TLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHC 536
Score = 46.0 bits (104), Expect = 8e-04
Identities = 65/283 (22%), Positives = 107/283 (37%), Gaps = 25/283 (8%)
Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNV--ILADEGEYSCEAENSV 278
+C G+P P W + R+ ++ G+ R+ N I +G+Y C A N +
Sbjct: 56 ECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFRIPNEGHISHFQGKYRCFASNKL 115
Query: 279 G-AVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTII 335
G A+S V P + + VE G+ C G P ++W I
Sbjct: 116 GIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWM-----NIE 170
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSD 392
+ +D+ L + ++ DSRN C A + V+ KLTV S
Sbjct: 171 LEHIEQDE---RVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSS 227
Query: 393 DD----RP----PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
+ +P PP + S+ T+ + + C A P P + W G L +
Sbjct: 228 NSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREA 287
Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
TL ++++ D G Y C AS+ G ++V+ P
Sbjct: 288 KENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEP 330
Score = 39.9 bits (89), Expect = 0.054
Identities = 44/168 (26%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
I L + +Y+F +I + +PS S +T PD P NI + + +KW
Sbjct: 673 ILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKW 732
Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
P + QNG G V W P + TV T +MT Y V++ A
Sbjct: 733 EPLKSMEQNG--PGLEYRVTW--KPQGAPVEWEEETVTNHTLRVMTPAVY-APYDVKVQA 787
Query: 813 ETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
+G GP Q V + G D P+ V ++ V TW
Sbjct: 788 INQLGSGPDPQSV-----TLYSGEDYPDTAPVIHGVDVINSTLVKVTW 830
>BC071557-1|AAH71557.1| 1070|Homo sapiens PTK7 protein tyrosine
kinase 7 protein.
Length = 1070
Score = 146 bits (354), Expect = 4e-34
Identities = 127/486 (26%), Positives = 209/486 (43%), Gaps = 37/486 (7%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
++ P DV VAR++ A +C+ P P+++W +++ R+ + A G
Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
L R +AG+Y C G ATLH+A + + EP + + V
Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG
Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
R + + + P + P+D + G C P P V+W R+ +
Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VES 306
R +V +G+LR+++V + D Y C + G++ A + V + P +E
Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
A C+ATGR +PT+ W G S ++ V D L ++D+
Sbjct: 517 DKEATVPCSATGREKPTIKWERAD-------GSSLPEW----VTDNAGTLHFARVTRDDA 565
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
N ++ G +LTV P T+ A+ C A P+
Sbjct: 566 GNYTCIASNGPQGQIRAHVQLTVAVFIT-----FKVEPERTTVYQGHTALLQCEAQGDPK 620
Query: 427 PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVA-SSRHGKYVWSGAL 482
P+I W + L R ++ +G+LV+ D+ DSG YTC+A +S + K+ +
Sbjct: 621 PLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLY 680
Query: 483 LVDSPI 488
+VD P+
Sbjct: 681 VVDKPV 686
Score = 112 bits (270), Expect = 6e-24
Identities = 106/373 (28%), Positives = 155/373 (41%), Gaps = 28/373 (7%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P P++ W GV + TH + G L SDAGVY C A N G R
Sbjct: 348 GLPEPSVWWEHAGVRL--PTHGRVYQKGHELVLANI---AESDAGVYTCHAANLAGQRR- 401
Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156
++ + VA + + +P+ Q +G L+CL + +P+P V W +N +L DSR
Sbjct: 402 QDVNITVATVPSWLK-KPQDSQLEEGKPGYLDCLT-QATPKPTVVWYRN--QMLISEDSR 457
Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE-DVVAQT 215
+ G L I D Y+C++ AG+ E A A +++ K P+ +
Sbjct: 458 FEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIE-AQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEA 274
T C G P + W R A G ++P V D+ G+L V D G Y+C A
Sbjct: 517 DKEATVPCSATGREKPTIKWER-ADGSSLPEW---VTDNAGTLHFARVTRDDAGNYTCIA 572
Query: 275 ENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
N G + A LTV + + P V G+ A C A G P+P + W +G
Sbjct: 573 SNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW--KGKDR 630
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
I+ P + H +F + L I+D DS C A N L V
Sbjct: 631 ILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCIAGNSCNIKHTEAPLYVV--- 682
Query: 394 DRPPPIITNGPSN 406
D+P P + GP +
Sbjct: 683 DKPVPEESEGPGS 695
Score = 108 bits (260), Expect = 1e-22
Identities = 127/474 (26%), Positives = 191/474 (40%), Gaps = 41/474 (8%)
Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69
P +++ P + + TL C G P P +W++ G L ++ ++ L
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187
Query: 70 RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125
R G HS G+Y C A +++G A S+N TL +A E F L P+ A+ +
Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180
+ C P P++ W +T + + HL G+L++ R +AG Y+C
Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
I + G ATL + I+ + P A + VT G P P V W +
Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359
Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
G +P GRV L L N+ +D G Y+C A N G +TV PS
Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P +E G C P+PT+ W N+ +I S D VF T L I
Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW--YRNQMLI----SEDS--RFEVFKNGT-LRI 468
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N + D C + AGS + ++ V PP Q + A P
Sbjct: 469 NSVEVYDG-TWYRCMSSTPAGSIEAQARVQVLEKLKFTPP----PQPQQCMEFDKEATVP 523
Query: 419 CTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
C+A +P I W +G +L + N GTL + + D+G YTC+AS+
Sbjct: 524 CSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTCIASN 574
Score = 101 bits (242), Expect = 2e-20
Identities = 124/479 (25%), Positives = 185/479 (38%), Gaps = 44/479 (9%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+QP + + A L C +P P + W G V DT R L F
Sbjct: 35 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSFAAVDR 92
Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128
+ D+G + C A + ARS NA+ ++ + P S+ Q T V L
Sbjct: 93 PQ---DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
C G P P W ++G T L DG S H V NL ++ A +G Y C A +A
Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
G S TL I + + ++ P+DVV F C+ P P + W
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266
Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296
+ P L R V +GSL L V + G Y C + G + L + + +
Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
L V +G+ R TC G PEP+++W G R P R V+
Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L + + ++D+ C A N AG +TV + P P + L
Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G
Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488
Score = 92.3 bits (219), Expect = 1e-17
Identities = 78/296 (26%), Positives = 119/296 (40%), Gaps = 18/296 (6%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +T P +++P D + +P L+C +P P + WY+ +L+ D+ +
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ 121
G L R V+ D Y C ++ G S A V VL + +F P+ +Q +
Sbjct: 463 NGTL---RINSVEVY-DGTWYRCMSSTPAG---SIEAQARVQVLEKLKFTPPPQPQQCME 515
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQ 179
D G +P + W++ DG S V + G L + DAG Y
Sbjct: 516 FDKEATVPCSATGREKPTIKWERA------DGSSLPEWVTDNAGTLHFARVTRDDAGNYT 569
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RS 238
CIA N + A L + + PE G + QC GDP P + W+ +
Sbjct: 570 CIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKD 629
Query: 239 AGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
LG R+ + +GSL + +V D G Y+C A NS L V D P
Sbjct: 630 RILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685
Score = 83.4 bits (197), Expect = 4e-15
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +P S+ + QG +L C P +VYW +G + D+ G +L
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89
Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222
R D+G +QC+AR+ E+ A +IK P ++ P + Q + VT +
Sbjct: 90 VDRPQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280
C + G P P W R + V + +L L G YSC A ++ G A
Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209
Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
S+ + L++ D + L+P V V A F C + +P P++ W E I
Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396
AT +G +LT + + C G + L + +D P
Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451
P + T G + LP K + PEP + W G L H R
Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375
Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
LVL ++ +SD+G YTC A++ G+
Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399
>AL355385-4|CAI13783.1| 1070|Homo sapiens PTK7 protein tyrosine
kinase 7 protein.
Length = 1070
Score = 146 bits (354), Expect = 4e-34
Identities = 127/486 (26%), Positives = 209/486 (43%), Gaps = 37/486 (7%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
++ P DV VAR++ A +C+ P P+++W +++ R+ + A G
Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
L R +AG+Y C G ATLH+A + + EP + + V
Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG
Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
R + + + P + P+D + G C P P V+W R+ +
Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VES 306
R +V +G+LR+++V + D Y C + G++ A + V + P +E
Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
A C+ATGR +PT+ W G S ++ V D L ++D+
Sbjct: 517 DKEATVPCSATGREKPTIKWERAD-------GSSLPEW----VTDNAGTLHFARVTRDDA 565
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
N ++ G +LTV P T+ A+ C A P+
Sbjct: 566 GNYTCIASNGPQGQIRAHVQLTVAVFIT-----FKVEPERTTVYQGHTALLQCEAQGDPK 620
Query: 427 PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVA-SSRHGKYVWSGAL 482
P+I W + L R ++ +G+LV+ D+ DSG YTC+A +S + K+ +
Sbjct: 621 PLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLY 680
Query: 483 LVDSPI 488
+VD P+
Sbjct: 681 VVDKPV 686
Score = 112 bits (270), Expect = 6e-24
Identities = 106/373 (28%), Positives = 155/373 (41%), Gaps = 28/373 (7%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P P++ W GV + TH + G L SDAGVY C A N G R
Sbjct: 348 GLPEPSVWWEHAGVRL--PTHGRVYQKGHELVLANI---AESDAGVYTCHAANLAGQRR- 401
Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156
++ + VA + + +P+ Q +G L+CL + +P+P V W +N +L DSR
Sbjct: 402 QDVNITVATVPSWLK-KPQDSQLEEGKPGYLDCLT-QATPKPTVVWYRN--QMLISEDSR 457
Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE-DVVAQT 215
+ G L I D Y+C++ AG+ E A A +++ K P+ +
Sbjct: 458 FEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIE-AQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEA 274
T C G P + W R A G ++P V D+ G+L V D G Y+C A
Sbjct: 517 DKEATVPCSATGREKPTIKWER-ADGSSLPEW---VTDNAGTLHFARVTRDDAGNYTCIA 572
Query: 275 ENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
N G + A LTV + + P V G+ A C A G P+P + W +G
Sbjct: 573 SNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW--KGKDR 630
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
I+ P + H +F + L I+D DS C A N L V
Sbjct: 631 ILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCIAGNSCNIKHTEAPLYVV--- 682
Query: 394 DRPPPIITNGPSN 406
D+P P + GP +
Sbjct: 683 DKPVPEESEGPGS 695
Score = 108 bits (260), Expect = 1e-22
Identities = 127/474 (26%), Positives = 191/474 (40%), Gaps = 41/474 (8%)
Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69
P +++ P + + TL C G P P +W++ G L ++ ++ L
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187
Query: 70 RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125
R G HS G+Y C A +++G A S+N TL +A E F L P+ A+ +
Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180
+ C P P++ W +T + + HL G+L++ R +AG Y+C
Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
I + G ATL + I+ + P A + VT G P P V W +
Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359
Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
G +P GRV L L N+ +D G Y+C A N G +TV PS
Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P +E G C P+PT+ W N+ +I S D VF T L I
Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW--YRNQMLI----SEDS--RFEVFKNGT-LRI 468
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N + D C + AGS + ++ V PP Q + A P
Sbjct: 469 NSVEVYDG-TWYRCMSSTPAGSIEAQARVQVLEKLKFTPP----PQPQQCMEFDKEATVP 523
Query: 419 CTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
C+A +P I W +G +L + N GTL + + D+G YTC+AS+
Sbjct: 524 CSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTCIASN 574
Score = 101 bits (243), Expect = 1e-20
Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+QP + + A L C +P P + W G V DT R L F A
Sbjct: 35 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 90
Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128
R+ D+G + C A + ARS NA+ ++ + P S+ Q T V L
Sbjct: 91 DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
C G P P W ++G T L DG S H V NL ++ A +G Y C A +A
Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
G S TL I + + ++ P+DVV F C+ P P + W
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266
Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296
+ P L R V +GSL L V + G Y C + G + L + + +
Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
L V +G+ R TC G PEP+++W G R P R V+
Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L + + ++D+ C A N AG +TV + P P + L
Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G
Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488
Score = 92.3 bits (219), Expect = 1e-17
Identities = 78/296 (26%), Positives = 119/296 (40%), Gaps = 18/296 (6%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +T P +++P D + +P L+C +P P + WY+ +L+ D+ +
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ 121
G L R V+ D Y C ++ G S A V VL + +F P+ +Q +
Sbjct: 463 NGTL---RINSVEVY-DGTWYRCMSSTPAG---SIEAQARVQVLEKLKFTPPPQPQQCME 515
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQ 179
D G +P + W++ DG S V + G L + DAG Y
Sbjct: 516 FDKEATVPCSATGREKPTIKWERA------DGSSLPEWVTDNAGTLHFARVTRDDAGNYT 569
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RS 238
CIA N + A L + + PE G + QC GDP P + W+ +
Sbjct: 570 CIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKD 629
Query: 239 AGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
LG R+ + +GSL + +V D G Y+C A NS L V D P
Sbjct: 630 RILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685
Score = 83.0 bits (196), Expect = 6e-15
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +P S+ + QG +L C P +VYW +G + D+ G +L
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89
Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222
R D+G +QC+AR+ E+ A +IK P ++ P + Q + VT +
Sbjct: 90 VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280
C + G P P W R + V + +L L G YSC A ++ G A
Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209
Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
S+ + L++ D + L+P V V A F C + +P P++ W E I
Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396
AT +G +LT + + C G + L + +D P
Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451
P + T G + LP K + PEP + W G L H R
Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375
Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
LVL ++ +SD+G YTC A++ G+
Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399
>AF531872-1|AAN04866.1| 816|Homo sapiens transmembrane receptor
precursor PTK7-5 protein.
Length = 816
Score = 146 bits (354), Expect = 4e-34
Identities = 127/486 (26%), Positives = 209/486 (43%), Gaps = 37/486 (7%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
++ P DV VAR++ A +C+ P P+++W +++ R+ + A G
Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
L R +AG+Y C G ATLH+A + + EP + + V
Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG
Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
R + + + P + P+D + G C P P V+W R+ +
Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VES 306
R +V +G+LR+++V + D Y C + G++ A + V + P +E
Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
A C+ATGR +PT+ W G S ++ V D L ++D+
Sbjct: 517 DKEATVPCSATGREKPTIKWERAD-------GSSLPEW----VTDNAGTLHFARVTRDDA 565
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
N ++ G +LTV P T+ A+ C A P+
Sbjct: 566 GNYTCIASNGPQGQIRAHVQLTVAVFIT-----FKVEPERTTVYQGHTALLQCEAQGDPK 620
Query: 427 PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVA-SSRHGKYVWSGAL 482
P+I W + L R ++ +G+LV+ D+ DSG YTC+A +S + K+ +
Sbjct: 621 PLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLY 680
Query: 483 LVDSPI 488
+VD P+
Sbjct: 681 VVDKPV 686
Score = 112 bits (270), Expect = 6e-24
Identities = 106/373 (28%), Positives = 155/373 (41%), Gaps = 28/373 (7%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P P++ W GV + TH + G L SDAGVY C A N G R
Sbjct: 348 GLPEPSVWWEHAGVRL--PTHGRVYQKGHELVLANI---AESDAGVYTCHAANLAGQRR- 401
Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156
++ + VA + + +P+ Q +G L+CL + +P+P V W +N +L DSR
Sbjct: 402 QDVNITVATVPSWLK-KPQDSQLEEGKPGYLDCLT-QATPKPTVVWYRN--QMLISEDSR 457
Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE-DVVAQT 215
+ G L I D Y+C++ AG+ E A A +++ K P+ +
Sbjct: 458 FEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIE-AQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEA 274
T C G P + W R A G ++P V D+ G+L V D G Y+C A
Sbjct: 517 DKEATVPCSATGREKPTIKWER-ADGSSLPEW---VTDNAGTLHFARVTRDDAGNYTCIA 572
Query: 275 ENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
N G + A LTV + + P V G+ A C A G P+P + W +G
Sbjct: 573 SNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW--KGKDR 630
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
I+ P + H +F + L I+D DS C A N L V
Sbjct: 631 ILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCIAGNSCNIKHTEAPLYVV--- 682
Query: 394 DRPPPIITNGPSN 406
D+P P + GP +
Sbjct: 683 DKPVPEESEGPGS 695
Score = 108 bits (260), Expect = 1e-22
Identities = 127/474 (26%), Positives = 191/474 (40%), Gaps = 41/474 (8%)
Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69
P +++ P + + TL C G P P +W++ G L ++ ++ L
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187
Query: 70 RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125
R G HS G+Y C A +++G A S+N TL +A E F L P+ A+ +
Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180
+ C P P++ W +T + + HL G+L++ R +AG Y+C
Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
I + G ATL + I+ + P A + VT G P P V W +
Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359
Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
G +P GRV L L N+ +D G Y+C A N G +TV PS
Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P +E G C P+PT+ W N+ +I S D VF T L I
Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW--YRNQMLI----SEDS--RFEVFKNGT-LRI 468
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N + D C + AGS + ++ V PP Q + A P
Sbjct: 469 NSVEVYDG-TWYRCMSSTPAGSIEAQARVQVLEKLKFTPP----PQPQQCMEFDKEATVP 523
Query: 419 CTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
C+A +P I W +G +L + N GTL + + D+G YTC+AS+
Sbjct: 524 CSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTCIASN 574
Score = 101 bits (243), Expect = 1e-20
Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+QP + + A L C +P P + W G V DT R L F A
Sbjct: 35 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 90
Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128
R+ D+G + C A + ARS NA+ ++ + P S+ Q T V L
Sbjct: 91 DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
C G P P W ++G T L DG S H V NL ++ A +G Y C A +A
Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
G S TL I + + ++ P+DVV F C+ P P + W
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266
Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296
+ P L R V +GSL L V + G Y C + G + L + + +
Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
L V +G+ R TC G PEP+++W G R P R V+
Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L + + ++D+ C A N AG +TV + P P + L
Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G
Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488
Score = 92.3 bits (219), Expect = 1e-17
Identities = 78/296 (26%), Positives = 119/296 (40%), Gaps = 18/296 (6%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +T P +++P D + +P L+C +P P + WY+ +L+ D+ +
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ 121
G L R V+ D Y C ++ G S A V VL + +F P+ +Q +
Sbjct: 463 NGTL---RINSVEVY-DGTWYRCMSSTPAG---SIEAQARVQVLEKLKFTPPPQPQQCME 515
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQ 179
D G +P + W++ DG S V + G L + DAG Y
Sbjct: 516 FDKEATVPCSATGREKPTIKWERA------DGSSLPEWVTDNAGTLHFARVTRDDAGNYT 569
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RS 238
CIA N + A L + + PE G + QC GDP P + W+ +
Sbjct: 570 CIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKD 629
Query: 239 AGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
LG R+ + +GSL + +V D G Y+C A NS L V D P
Sbjct: 630 RILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685
Score = 83.0 bits (196), Expect = 6e-15
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +P S+ + QG +L C P +VYW +G + D+ G +L
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89
Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222
R D+G +QC+AR+ E+ A +IK P ++ P + Q + VT +
Sbjct: 90 VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280
C + G P P W R + V + +L L G YSC A ++ G A
Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209
Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
S+ + L++ D + L+P V V A F C + +P P++ W E I
Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396
AT +G +LT + + C G + L + +D P
Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451
P + T G + LP K + PEP + W G L H R
Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375
Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
LVL ++ +SD+G YTC A++ G+
Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399
>AF531868-1|AAN04862.1| 1070|Homo sapiens transmembrane receptor
precursor PTK7-1 protein.
Length = 1070
Score = 146 bits (354), Expect = 4e-34
Identities = 127/486 (26%), Positives = 209/486 (43%), Gaps = 37/486 (7%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
++ P DV VAR++ A +C+ P P+++W +++ R+ + A G
Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
L R +AG+Y C G ATLH+A + + EP + + V
Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG
Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
R + + + P + P+D + G C P P V+W R+ +
Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VES 306
R +V +G+LR+++V + D Y C + G++ A + V + P +E
Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
A C+ATGR +PT+ W G S ++ V D L ++D+
Sbjct: 517 DKEATVPCSATGREKPTIKWERAD-------GSSLPEW----VTDNAGTLHFARVTRDDA 565
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
N ++ G +LTV P T+ A+ C A P+
Sbjct: 566 GNYTCIASNGPQGQIRAHVQLTVAVFIT-----FKVEPERTTVYQGHTALLQCEAQGDPK 620
Query: 427 PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVA-SSRHGKYVWSGAL 482
P+I W + L R ++ +G+LV+ D+ DSG YTC+A +S + K+ +
Sbjct: 621 PLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLY 680
Query: 483 LVDSPI 488
+VD P+
Sbjct: 681 VVDKPV 686
Score = 112 bits (270), Expect = 6e-24
Identities = 106/373 (28%), Positives = 155/373 (41%), Gaps = 28/373 (7%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P P++ W GV + TH + G L SDAGVY C A N G R
Sbjct: 348 GLPEPSVWWEHAGVRL--PTHGRVYQKGHELVLANI---AESDAGVYTCHAANLAGQRR- 401
Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156
++ + VA + + +P+ Q +G L+CL + +P+P V W +N +L DSR
Sbjct: 402 QDVNITVATVPSWLK-KPQDSQLEEGKPGYLDCLT-QATPKPTVVWYRN--QMLISEDSR 457
Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE-DVVAQT 215
+ G L I D Y+C++ AG+ E A A +++ K P+ +
Sbjct: 458 FEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIE-AQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEA 274
T C G P + W R A G ++P V D+ G+L V D G Y+C A
Sbjct: 517 DKEATVPCSATGREKPTIKWER-ADGSSLPEW---VTDNAGTLHFARVTRDDAGNYTCIA 572
Query: 275 ENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
N G + A LTV + + P V G+ A C A G P+P + W +G
Sbjct: 573 SNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW--KGKDR 630
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
I+ P + H +F + L I+D DS C A N L V
Sbjct: 631 ILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCIAGNSCNIKHTEAPLYVV--- 682
Query: 394 DRPPPIITNGPSN 406
D+P P + GP +
Sbjct: 683 DKPVPEESEGPGS 695
Score = 108 bits (260), Expect = 1e-22
Identities = 127/474 (26%), Positives = 191/474 (40%), Gaps = 41/474 (8%)
Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69
P +++ P + + TL C G P P +W++ G L ++ ++ L
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187
Query: 70 RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125
R G HS G+Y C A +++G A S+N TL +A E F L P+ A+ +
Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180
+ C P P++ W +T + + HL G+L++ R +AG Y+C
Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
I + G ATL + I+ + P A + VT G P P V W +
Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359
Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
G +P GRV L L N+ +D G Y+C A N G +TV PS
Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P +E G C P+PT+ W N+ +I S D VF T L I
Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW--YRNQMLI----SEDS--RFEVFKNGT-LRI 468
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N + D C + AGS + ++ V PP Q + A P
Sbjct: 469 NSVEVYDG-TWYRCMSSTPAGSIEAQARVQVLEKLKFTPP----PQPQQCMEFDKEATVP 523
Query: 419 CTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
C+A +P I W +G +L + N GTL + + D+G YTC+AS+
Sbjct: 524 CSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTCIASN 574
Score = 101 bits (243), Expect = 1e-20
Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+QP + + A L C +P P + W G V DT R L F A
Sbjct: 35 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 90
Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128
R+ D+G + C A + ARS NA+ ++ + P S+ Q T V L
Sbjct: 91 DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
C G P P W ++G T L DG S H V NL ++ A +G Y C A +A
Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
G S TL I + + ++ P+DVV F C+ P P + W
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266
Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296
+ P L R V +GSL L V + G Y C + G + L + + +
Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
L V +G+ R TC G PEP+++W G R P R V+
Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L + + ++D+ C A N AG +TV + P P + L
Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G
Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488
Score = 92.3 bits (219), Expect = 1e-17
Identities = 78/296 (26%), Positives = 119/296 (40%), Gaps = 18/296 (6%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +T P +++P D + +P L+C +P P + WY+ +L+ D+ +
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ 121
G L R V+ D Y C ++ G S A V VL + +F P+ +Q +
Sbjct: 463 NGTL---RINSVEVY-DGTWYRCMSSTPAG---SIEAQARVQVLEKLKFTPPPQPQQCME 515
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQ 179
D G +P + W++ DG S V + G L + DAG Y
Sbjct: 516 FDKEATVPCSATGREKPTIKWERA------DGSSLPEWVTDNAGTLHFARVTRDDAGNYT 569
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RS 238
CIA N + A L + + PE G + QC GDP P + W+ +
Sbjct: 570 CIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKD 629
Query: 239 AGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
LG R+ + +GSL + +V D G Y+C A NS L V D P
Sbjct: 630 RILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685
Score = 83.0 bits (196), Expect = 6e-15
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +P S+ + QG +L C P +VYW +G + D+ G +L
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89
Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222
R D+G +QC+AR+ E+ A +IK P ++ P + Q + VT +
Sbjct: 90 VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280
C + G P P W R + V + +L L G YSC A ++ G A
Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209
Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
S+ + L++ D + L+P V V A F C + +P P++ W E I
Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396
AT +G +LT + + C G + L + +D P
Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451
P + T G + LP K + PEP + W G L H R
Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375
Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
LVL ++ +SD+G YTC A++ G+
Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399
>AF447176-1|AAL39062.1| 1070|Homo sapiens protein tyrosine kinase-7
protein.
Length = 1070
Score = 146 bits (354), Expect = 4e-34
Identities = 127/486 (26%), Positives = 209/486 (43%), Gaps = 37/486 (7%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
++ P DV VAR++ A +C+ P P+++W +++ R+ + A G
Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
L R +AG+Y C G ATLH+A + + EP + + V
Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG
Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
R + + + P + P+D + G C P P V+W R+ +
Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VES 306
R +V +G+LR+++V + D Y C + G++ A + V + P +E
Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
A C+ATGR +PT+ W G S ++ V D L ++D+
Sbjct: 517 DKEATVPCSATGREKPTIKWERAD-------GSSLPEW----VTDNAGTLHFARVTRDDA 565
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
N ++ G +LTV P T+ A+ C A P+
Sbjct: 566 GNYTCIASNGPQGQIRAHVQLTVAVFIT-----FKVEPERTTVYQGHTALLQCEAQGDPK 620
Query: 427 PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVA-SSRHGKYVWSGAL 482
P+I W + L R ++ +G+LV+ D+ DSG YTC+A +S + K+ +
Sbjct: 621 PLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLY 680
Query: 483 LVDSPI 488
+VD P+
Sbjct: 681 VVDKPV 686
Score = 112 bits (270), Expect = 6e-24
Identities = 106/373 (28%), Positives = 155/373 (41%), Gaps = 28/373 (7%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P P++ W GV + TH + G L SDAGVY C A N G R
Sbjct: 348 GLPEPSVWWEHAGVRL--PTHGRVYQKGHELVLANI---AESDAGVYTCHAANLAGQRR- 401
Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156
++ + VA + + +P+ Q +G L+CL + +P+P V W +N +L DSR
Sbjct: 402 QDVNITVATVPSWLK-KPQDSQLEEGKPGYLDCLT-QATPKPTVVWYRN--QMLISEDSR 457
Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE-DVVAQT 215
+ G L I D Y+C++ AG+ E A A +++ K P+ +
Sbjct: 458 FEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIE-AQARVQVLEKLKFTPPPQPQQCMEF 516
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEA 274
T C G P + W R A G ++P V D+ G+L V D G Y+C A
Sbjct: 517 DKEATVPCSATGREKPTIKWER-ADGSSLPEW---VTDNAGTLHFARVTRDDAGNYTCIA 572
Query: 275 ENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
N G + A LTV + + P V G+ A C A G P+P + W +G
Sbjct: 573 SNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW--KGKDR 630
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
I+ P + H +F + L I+D DS C A N L V
Sbjct: 631 ILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCIAGNSCNIKHTEAPLYVV--- 682
Query: 394 DRPPPIITNGPSN 406
D+P P + GP +
Sbjct: 683 DKPVPEESEGPGS 695
Score = 108 bits (260), Expect = 1e-22
Identities = 127/474 (26%), Positives = 191/474 (40%), Gaps = 41/474 (8%)
Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69
P +++ P + + TL C G P P +W++ G L ++ ++ L
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187
Query: 70 RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125
R G HS G+Y C A +++G A S+N TL +A E F L P+ A+ +
Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180
+ C P P++ W +T + + HL G+L++ R +AG Y+C
Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
I + G ATL + I+ + P A + VT G P P V W +
Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359
Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
G +P GRV L L N+ +D G Y+C A N G +TV PS
Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P +E G C P+PT+ W N+ +I S D VF T L I
Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW--YRNQMLI----SEDS--RFEVFKNGT-LRI 468
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N + D C + AGS + ++ V PP Q + A P
Sbjct: 469 NSVEVYDG-TWYRCMSSTPAGSIEAQARVQVLEKLKFTPP----PQPQQCMEFDKEATVP 523
Query: 419 CTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
C+A +P I W +G +L + N GTL + + D+G YTC+AS+
Sbjct: 524 CSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTCIASN 574
Score = 101 bits (243), Expect = 1e-20
Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+QP + + A L C +P P + W G V DT R L F A
Sbjct: 35 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 90
Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128
R+ D+G + C A + ARS NA+ ++ + P S+ Q T V L
Sbjct: 91 DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
C G P P W ++G T L DG S H V NL ++ A +G Y C A +A
Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
G S TL I + + ++ P+DVV F C+ P P + W
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266
Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296
+ P L R V +GSL L V + G Y C + G + L + + +
Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
L V +G+ R TC G PEP+++W G R P R V+
Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L + + ++D+ C A N AG +TV + P P + L
Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G
Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488
Score = 92.3 bits (219), Expect = 1e-17
Identities = 78/296 (26%), Positives = 119/296 (40%), Gaps = 18/296 (6%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +T P +++P D + +P L+C +P P + WY+ +L+ D+ +
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ 121
G L R V+ D Y C ++ G S A V VL + +F P+ +Q +
Sbjct: 463 NGTL---RINSVEVY-DGTWYRCMSSTPAG---SIEAQARVQVLEKLKFTPPPQPQQCME 515
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQ 179
D G +P + W++ DG S V + G L + DAG Y
Sbjct: 516 FDKEATVPCSATGREKPTIKWERA------DGSSLPEWVTDNAGTLHFARVTRDDAGNYT 569
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RS 238
CIA N + A L + + PE G + QC GDP P + W+ +
Sbjct: 570 CIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKD 629
Query: 239 AGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
LG R+ + +GSL + +V D G Y+C A NS L V D P
Sbjct: 630 RILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685
Score = 83.0 bits (196), Expect = 6e-15
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +P S+ + QG +L C P +VYW +G + D+ G +L
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89
Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222
R D+G +QC+AR+ E+ A +IK P ++ P + Q + VT +
Sbjct: 90 VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280
C + G P P W R + V + +L L G YSC A ++ G A
Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209
Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
S+ + L++ D + L+P V V A F C + +P P++ W E I
Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396
AT +G +LT + + C G + L + +D P
Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451
P + T G + LP K + PEP + W G L H R
Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375
Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
LVL ++ +SD+G YTC A++ G+
Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399
>AB209329-1|BAD92566.1| 1210|Homo sapiens Neural cell adhesion
molecule variant protein.
Length = 1210
Score = 146 bits (354), Expect = 4e-34
Identities = 120/485 (24%), Positives = 200/485 (41%), Gaps = 34/485 (7%)
Query: 10 EAPYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P II+Q + V + + C A G+P P W K G HR I F
Sbjct: 35 QVPTIIKQSKVQVAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTF 94
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
G + G Y C A+N G A S V + + + + + + +GD +VL
Sbjct: 95 RIPNEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLP 154
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIARNAAG 187
C PP+G P ++YW N + + D R+++ G+L + + D+ Y C A
Sbjct: 155 CNPPKGLPPLHIYWM-NIELEHIEQDERVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRL 213
Query: 188 TRESAIATLKIHI---------KPYLITGPEDVVAQT------GSSVTFQCRVGGDPLPD 232
+K+ + KP L+ P + +++ G + +C G P P
Sbjct: 214 RTIVQKMPMKLTVNSSNSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQ 273
Query: 233 VLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
V W + GG++P GR + G +L+++NV D+G Y C A N +G + ++ V +
Sbjct: 274 VDWNKI--GGDLPKGREAKENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEE 331
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP P S +G+ C A G P+PT+ W V G+ P + VF
Sbjct: 332 PPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPVDNHP------FAGDVVFP 385
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
++ + N + C A N G+ + V D P I T N +
Sbjct: 386 --REISFTNLQPNHTA-VYQCEASNVHGTILANANIDVV---DVRPLIQTKDGENYATVV 439
Query: 412 KSMAVFPCTAICTPEPIIAWY-FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
A C +PE +++W E ++ R ++ +GTL + + D+G+Y+C
Sbjct: 440 GYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENGTLQINRTTEEDAGSYSCWVE 499
Query: 471 SRHGK 475
+ GK
Sbjct: 500 NAIGK 504
Score = 99 bits (238), Expect = 5e-20
Identities = 167/723 (23%), Positives = 264/723 (36%), Gaps = 83/723 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+G+ ++LEC G P P V W K G L +++ + G L I++ D G Y+C
Sbjct: 256 KGEILLLECFA-EGLPTPQVDWNKIGGDLPKGREAKENY--GKTLKIENVSYQDKGNYRC 312
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
A N GT + + P P+ V TGS+ C G+P P + WR +
Sbjct: 313 TASNFLGTATHDFHVI-VEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGS 371
Query: 241 G-GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
N P V+ + N+ Y CEA N G + A+ + V D + +
Sbjct: 372 PVDNHPFAG-DVVFPREISFTNLQPNHTAVYQCEASNVHGTILANANIDVVDVRPLIQTK 430
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
+ N + G A C PE + W + P R +YH +++ T L
Sbjct: 431 DGENYATVVGYSAFLHCEFFASPEAVVSWQKVEE---VKPLEGR-RYH---IYENGT-LQ 482
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
IN T + D+ + C N G + V L D R + P N +P M
Sbjct: 483 INRTTEEDA-GSYSCWVENAIGKTAVTANL-----DIRNATKLRVSPKNPRIPKLHMLEL 536
Query: 418 PCTAICTPEPI----IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C + C ++W +GEA N T DG +++ + + S V
Sbjct: 537 HCESKCDSHLKHSLKLSWSKDGEAF----EINGTEDGRIIIDGANLTISN----VTLEDQ 588
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSS 533
G Y S +DS + V +P PP + SV L+W +S
Sbjct: 589 GIYCCSAHTALDSAAD-----ITQVTVLDVPDPPENLHLSERQNRSVRLTWEAGAD-HNS 642
Query: 534 SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSH 593
+I Y VE + G W + R + V+ L P + Y F V N
Sbjct: 643 NISEYIVEFEGNKEEPGR--------WEELTRVQGKKTTVILPLAPFVRYQFRVIAVNEV 694
Query: 594 GLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMW 653
G S PS SD T + NI ++A+ IK W
Sbjct: 695 GRSQPSQPSDH-----------HETPPAAPDRNPQNIR-------VQASQPKEMIIK--W 734
Query: 654 EILNFYYLEGLFIYFRPL---DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPF 710
E L G + +R +E+E +T+ + + + Y Y+ +
Sbjct: 735 EPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHT----LRVMTPAVYAPYDVKVQAI 790
Query: 711 YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVV 770
+ G S + +D PD P+ + ++N+T V + WS +G + GY
Sbjct: 791 NQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWSTVPKDRVHGRLKGYQ-- 848
Query: 771 VNW------LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824
+NW LD + V I Q S ++ +L + + + + A G GP S+
Sbjct: 849 INWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLTVLAYNSKGAGPESEP 908
Query: 825 VYF 827
F
Sbjct: 909 YIF 911
Score = 84.2 bits (199), Expect = 3e-15
Identities = 83/301 (27%), Positives = 124/301 (41%), Gaps = 20/301 (6%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +V E P ++P + L C A G P P I+W G V D H
Sbjct: 324 DFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGEPQPTIKWRVNGSPV--DNHPF--- 378
Query: 63 AGGLFFLR--ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQS 119
AG + F R + + VY CEA+N +GT + NA + V +R + + E+ +
Sbjct: 379 AGDVVFPREISFTNLQPNHTAVYQCEASNVHGTILA-NANIDVVDVRPLIQTKDGENYAT 437
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
G + L C SPE V W+K + +G R H+ + G L I + DAG Y
Sbjct: 438 VVGYSAFLHC-EFFASPEAVVSWQKVEEVKPLEG-RRYHIYENGTLQINRTTEEDAGSYS 495
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVL---W 235
C NA G + + A L I L P++ + C D L L W
Sbjct: 496 CWVENAIG-KTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHCESKCDSHLKHSLKLSW 554
Query: 236 RRSAGG---GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ GR+ ++D +L + NV L D+G Y C A ++ + + +TV D
Sbjct: 555 SKDGEAFEINGTEDGRI-IIDGANLTISNVTLEDQGIYCCSAHTALDSAADITQVTVLDV 613
Query: 293 P 293
P
Sbjct: 614 P 614
Score = 82.6 bits (195), Expect = 8e-15
Identities = 69/299 (23%), Positives = 119/299 (39%), Gaps = 17/299 (5%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+T+ + + L C A G P+P + W K G D + + D
Sbjct: 252 ITILKGEILLLECFAEGLPTPQVDWNKIG----GDLPKGREAKENYGKTLKIENVSYQDK 307
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
G Y C A+N GTA HV V + +P+S + G +L C G P+P
Sbjct: 308 GNYRCTASNFLGTATH---DFHVIVEEPPRWTKKPQSAVYSTGSNGILLC-EAEGEPQPT 363
Query: 140 VYWKKNGQTL---LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
+ W+ NG + F GD +V + + + YQC A N GT +
Sbjct: 364 IKWRVNGSPVDNHPFAGD----VVFPREISFTNLQPNHTAVYQCEASNVHGTILANANID 419
Query: 197 KIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG 255
+ ++P + T E+ G S C P V W++ + R + ++G
Sbjct: 420 VVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIYENG 479
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
+L+++ D G YSC EN++G + + L + + + +SP + + ++ C
Sbjct: 480 TLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLELHC 538
Score = 46.0 bits (104), Expect = 8e-04
Identities = 65/283 (22%), Positives = 107/283 (37%), Gaps = 25/283 (8%)
Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNV--ILADEGEYSCEAENSV 278
+C G+P P W + R+ ++ G+ R+ N I +G+Y C A N +
Sbjct: 58 ECEAKGNPEPTFSWTKDGNPFYFTDHRIIPSNNSGTFRIPNEGHISHFQGKYRCFASNKL 117
Query: 279 G-AVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTII 335
G A+S V P + + VE G+ C G P ++W I
Sbjct: 118 GIAMSEEIEFIVPSVPKFPKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWM-----NIE 172
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG---KLTVTSD 392
+ +D+ L + ++ DSRN C A + V+ KLTV S
Sbjct: 173 LEHIEQDE---RVYMSQKGDLYFANVEEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSS 229
Query: 393 DD----RP----PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
+ +P PP + S+ T+ + + C A P P + W G L +
Sbjct: 230 NSIKQRKPKLLLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGREA 289
Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
TL ++++ D G Y C AS+ G ++V+ P
Sbjct: 290 KENYGKTLKIENVSYQDKGNYRCTASNFLGTATHDFHVIVEEP 332
Score = 39.9 bits (89), Expect = 0.054
Identities = 44/168 (26%), Positives = 64/168 (38%), Gaps = 11/168 (6%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
I L + +Y+F +I + +PS S +T PD P NI + + +KW
Sbjct: 675 ILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAPDRNPQNIRVQASQPKEMIIKW 734
Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
P + QNG G V W P + TV T +MT Y V++ A
Sbjct: 735 EPLKSMEQNG--PGLEYRVTW--KPQGAPVEWEEETVTNHTLRVMTPAVY-APYDVKVQA 789
Query: 813 ETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETW 860
+G GP Q V + G D P+ V ++ V TW
Sbjct: 790 INQLGSGPDPQSV-----TLYSGEDYPDTAPVIHGVDVINSTLVKVTW 832
>U33635-1|AAA87565.1| 1070|Homo sapiens colon carcinoma kinase-4
protein.
Length = 1070
Score = 145 bits (351), Expect = 1e-33
Identities = 127/486 (26%), Positives = 207/486 (42%), Gaps = 37/486 (7%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
++ P DV VAR++ A +C+ P P+++W +++ R+ + A G
Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
L R +AG+Y C G ATLH+A + + EP + + V
Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG
Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
R + + + P + P+D + G C P P V+W R+ +
Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES- 306
R +V +G+LR+++V + D Y C + G++ A L V + P
Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQAVLQVLEKLKFTPPPQPQQCMGF 516
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
A C+ATGR +PT+ W G S ++ V D L ++D+
Sbjct: 517 DKEATVPCSATGREKPTIKWERAD-------GSSLPEW----VTDNAGTLHFARVTRDDA 565
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
N ++ G +LTV P T+ A+ C A P+
Sbjct: 566 GNYTCIASNGPQGQIRAHVQLTVAVFIT-----FKVEPERTTVYQGHTALLQCEAQGDPK 620
Query: 427 PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVA-SSRHGKYVWSGAL 482
P+I W + L R ++ +G+LV+ D+ DSG YTC+A +S + K+ +
Sbjct: 621 PLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLY 680
Query: 483 LVDSPI 488
+VD P+
Sbjct: 681 VVDKPV 686
Score = 113 bits (272), Expect = 4e-24
Identities = 108/374 (28%), Positives = 156/374 (41%), Gaps = 30/374 (8%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P P++ W GV + TH + G L SDAGVY C A N G R
Sbjct: 348 GLPEPSVWWEHAGVRL--PTHGRVYQKGHELVLANI---AESDAGVYTCHAANLAGQRR- 401
Query: 97 RNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSR 156
++ + VA + + +P+ Q +G L+CL + +P+P V W +N +L DSR
Sbjct: 402 QDVNITVATVPSWLK-KPQDSQLEEGKPGYLDCLT-QATPKPTVVWYRN--QMLISEDSR 457
Query: 157 MHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTG 216
+ G L I D Y+C++ AG+ E A A L++ ++ T P G
Sbjct: 458 FEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIE-AQAVLQV-LEKLKFTPPPQPQQCMG 515
Query: 217 --SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCE 273
T C G P + W R A G ++P V D+ G+L V D G Y+C
Sbjct: 516 FDKEATVPCSATGREKPTIKWER-ADGSSLPEW---VTDNAGTLHFARVTRDDAGNYTCI 571
Query: 274 AENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
A N G + A LTV + + P V G+ A C A G P+P + W +G
Sbjct: 572 ASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQW--KGKD 629
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
I+ P + H +F + L I+D DS C A N L V
Sbjct: 630 RILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCIAGNSCNIKHTEAPLYVV-- 682
Query: 393 DDRPPPIITNGPSN 406
D+P P + GP +
Sbjct: 683 -DKPVPEESEGPGS 695
Score = 103 bits (248), Expect = 3e-21
Identities = 130/476 (27%), Positives = 191/476 (40%), Gaps = 45/476 (9%)
Query: 12 PYIIEQPLDVTVARHQPAT---LNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLF 67
P +++ P + A QP T L C G P P +W++ G L ++ ++
Sbjct: 128 PVVLKHP--ASEAEIQPQTQVKLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNL 185
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGD 123
LR G HS G+Y C A +++ A S+N TL +A E F L P+ A+ +
Sbjct: 186 TLRPA-GPEHS--GLYSCCAHSAFSQACSSQNFTLSIA--DESFARVVLAPQDVVVARYE 240
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRY 178
+ C P P++ W +T + + HL G+L++ R +AG Y
Sbjct: 241 EAMFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIY 299
Query: 179 QCIARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+CI + G ATL + I+ + P A + VT G P P V W
Sbjct: 300 RCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEH 358
Query: 238 SAGGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ G +P GRV L L N+ +D G Y+C A N G +TV PS
Sbjct: 359 A--GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWL 415
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
P +E G C P+PT+ W N+ +I S D VF T L
Sbjct: 416 KKPQDSQLEEGKPGYLDCLTQATPKPTVVW--YRNQMLI----SEDS--RFEVFKNGT-L 466
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
IN + D C + AGS + L V PP Q + A
Sbjct: 467 RINSVEVYDG-TWYRCMSSTPAGSIEAQAVLQVLEKLKFTPP----PQPQQCMGFDKEAT 521
Query: 417 FPCTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC+A +P I W +G +L + N GTL + + D+G YTC+AS+
Sbjct: 522 VPCSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTCIASN 574
Score = 96.7 bits (230), Expect = 4e-19
Identities = 121/478 (25%), Positives = 182/478 (38%), Gaps = 42/478 (8%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+QP + + A L C +P P + W G V DT R L F
Sbjct: 35 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSFAAVDP 92
Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVLEC 129
+ D+G + C A + ARS NA+ ++ + P S+ Q T V
Sbjct: 93 LQ---DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVKLR 149
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAG 187
G P P W ++G T L DG S H V NL ++ A +G Y C A +A
Sbjct: 150 CHIDGHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAFS 207
Query: 188 TR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAG 240
S TL I + + ++ P+DVV F C+ P P + W
Sbjct: 208 QACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPIT 267
Query: 241 GGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINL 297
+ P L R V +GSL L V + G Y C + G + L + + + L
Sbjct: 268 NRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMPL 327
Query: 298 SPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
V +G+ R TC G PEP+++W G R P R V+ L
Sbjct: 328 FEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHEL 376
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
+ + ++D+ C A N AG +TV + P P + L
Sbjct: 377 VLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPGY 430
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G
Sbjct: 431 LDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488
Score = 90.6 bits (215), Expect = 3e-17
Identities = 76/295 (25%), Positives = 120/295 (40%), Gaps = 16/295 (5%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +T P +++P D + +P L+C +P P + WY+ +L+ D+ +
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
G L R V+ D Y C ++ G+ ++ A L V + + +F P+ +Q
Sbjct: 463 NGTL---RINSVEVY-DGTWYRCMSSTPAGSIEAQ-AVLQV-LEKLKFTPPPQPQQCMGF 516
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQC 180
D G +P + W++ DG S V + G L + DAG Y C
Sbjct: 517 DKEATVPCSATGREKPTIKWERA------DGSSLPEWVTDNAGTLHFARVTRDDAGNYTC 570
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
IA N + A L + + PE G + QC GDP P + W+ +
Sbjct: 571 IASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDR 630
Query: 240 GGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
LG R+ + +GSL + +V D G Y+C A NS L V D P
Sbjct: 631 ILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKP 685
Score = 76.2 bits (179), Expect = 7e-13
Identities = 96/385 (24%), Positives = 150/385 (38%), Gaps = 38/385 (9%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ- 168
F +P S+ + QG +L C P +VYW +G + D+ G +L
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89
Query: 169 -DARQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTF 221
D Q D+G +QC+AR+ E+ A +IK P ++ P + Q + V
Sbjct: 90 VDPLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVKL 148
Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG- 279
+C + G P P W R + V + +L L G YSC A ++
Sbjct: 149 RCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFSQ 208
Query: 280 AVSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
A S+ + L++ D + L+P V V A F C + +P P++ W E I
Sbjct: 209 ACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITN 268
Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDR 395
AT +G +LT + + C G + L + +D
Sbjct: 269 RSRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDM 325
Query: 396 P---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG 450
P P + T G + LP K + PEP + W G L H R
Sbjct: 326 PLFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGH 374
Query: 451 TLVLKDLDKSDSGTYTCVASSRHGK 475
LVL ++ +SD+G YTC A++ G+
Sbjct: 375 ELVLANIAESDAGVYTCHAANLAGQ 399
>Z29373-1|CAA82564.1| 1257|Homo sapiens neural cell adhesion
molecule L1 protein.
Length = 1257
Score = 143 bits (347), Expect = 3e-33
Identities = 136/484 (28%), Positives = 202/484 (41%), Gaps = 37/484 (7%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAG 64
E P I EQ P + V +L C A G P RW + GV + P
Sbjct: 33 EPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHS 92
Query: 65 GLFFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G F + + G+Y C A+N GTA S L + + + + +G+
Sbjct: 93 GSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 152
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIA 182
+VVL C PP + +YW N + L D R+ + GNL + +D Y C A
Sbjct: 153 SVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA 211
Query: 183 RNAAGTR-----ESAIATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDP 229
+ GTR E +K I KP L+ +VA G + +C G P
Sbjct: 212 -HFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
P + W R +G MP RV + +L+L V D+GEY C AENS+G+ + Y+T
Sbjct: 271 TPTIKWLRPSGP--MPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 328
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
V P P S G AR C GRP+P + W + G I +++D+ +
Sbjct: 329 VEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--R 383
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
+ G +L ++ +D+ T C A N G + V P I+T
Sbjct: 384 IQRGALIL--SNVQPSDTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYM 437
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
S A C A P P + W E G ++Q+ R +GTL ++DL +D+G Y C
Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 497
Query: 468 VASS 471
+A++
Sbjct: 498 LAAN 501
Score = 127 bits (306), Expect = 3e-28
Identities = 159/609 (26%), Positives = 239/609 (39%), Gaps = 71/609 (11%)
Query: 21 VTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGG-LFFLRATHGRVHS 78
V V + L C S P I W +L + R + G L+F HS
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHS 205
Query: 79 DAGVYWCEA--TNSYGTARSRNATLHVAVL-----REEFRLEPESKQS----AQGDTVVL 127
D Y C A + + L V R+ L P + S QG +VL
Sbjct: 206 D---YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 262
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
EC+ G P P + W + + D + L + + D G Y+C+A N+ G
Sbjct: 263 ECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLG 319
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPL 246
+ A + + PY + P+ + G + C+V G P P+V WR +
Sbjct: 320 SARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK 378
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
+ + G+L L NV +D CEA N G + A+ Y+ V P+ L+ ++ +
Sbjct: 379 DQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMA 438
Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G+ A C A G P P++ W E T++ +++ A +G L I D N
Sbjct: 439 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LGIRDLQAN 490
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ C A N + + L V IT GP + S F C A
Sbjct: 491 DT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTFTCQASFD 544
Query: 425 P--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 545 PSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRA 604
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILG 537
LLV V S PGP + + H +T + V +SWS ++ I
Sbjct: 605 QLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED-HNAPIEK 647
Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
Y +E +E P W + + +QT +K L P + Y F V N +G
Sbjct: 648 YDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPG 698
Query: 597 GPSPVSDSV 605
PSPVS++V
Sbjct: 699 EPSPVSETV 707
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 326 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 385
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 386 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 440
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 441 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 497
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 498 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 555
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 556 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 612
Score = 40.7 bits (91), Expect = 0.031
Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+++ + YE + + +G + + +D P P + ILN++ V +KW
Sbjct: 775 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 834
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-----QATSLIMTNLTSGVSYSV 808
P +L G + GYNV W + K H TS+I++ L SY +
Sbjct: 835 PVDLAQVKGHLRGYNVTY-WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 893
Query: 809 QIAAETIIGLGPFSQ 823
++ A G GP S+
Sbjct: 894 EVQAFNGRGSGPASE 908
>M85289-1|AAA52700.1| 4391|Homo sapiens heparan sulfate proteoglycan
protein.
Length = 4391
Score = 143 bits (347), Expect = 3e-33
Identities = 151/515 (29%), Positives = 212/515 (41%), Gaps = 61/515 (11%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + + ++TV ATL C A GSP+P I W K + HR L L R
Sbjct: 3211 APQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQ-HR--LEGDTLIIPR 3267
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D+G Y C AT+ G A + LHV + PE G+TV L+CL
Sbjct: 3268 VAQ----QDSGQYICNATSPAGHAEA-TIILHVESPPYATTV-PEHASVQAGETVQLQCL 3321
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G+P W + G +L +R L L + A D+GRY+C N G+ E
Sbjct: 3322 A-HGTPPLTFQWSRVGSSLPGRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAE 3375
Query: 191 SAIATLKIHIKPYLITG--------------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
A A L + P + P+ G+SV F C V D + W
Sbjct: 3376 -AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDQGTQLRWF 3434
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-- 294
+ GG +P G + DG LR+ N+ + +G Y C+A G AS L + PS
Sbjct: 3435 KE--GGQLPPGHS--VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL 3490
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
IN+ + V G+ F C A G P+P + WS G + PG+ + V
Sbjct: 3491 INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH--LRPGIVQSG-------GVVR 3541
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
+ + D R C+A N AG++ L V + P I + P +P S
Sbjct: 3542 IAHVELADAGQYR----CTATNAAGTTQSHVLLLVQA----LPQI--SMPQEVRVPAGSA 3591
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
AVFPC A P P I+W +L + R + L+L + D+GTY C A++R G
Sbjct: 3592 AVFPCIASGYPTPDISWSKLDGSLPPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQG 3648
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
K L V + P +F S LP P K
Sbjct: 3649 KVKAFAHLQVPERVVP---YFTQTPYSFLPLPTIK 3680
Score = 130 bits (314), Expect = 3e-29
Identities = 125/488 (25%), Positives = 192/488 (39%), Gaps = 35/488 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+P I P TV + Q A+ C +P ++ W + + H I P G + +
Sbjct: 3021 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVH--ISPNGSIITI 3078
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
T H G Y C A+N+YG A+S N ++H + PE + G V L
Sbjct: 3079 VGTRPSNH---GTYRCVASNAYGVAQSVVNLSVHGP---PTVSVLPEGPVWVKVGKAVTL 3132
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
EC+ G P + W + T L+D L I A+ +DAG Y C+A+NA
Sbjct: 3133 ECVSA-GEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNAL 3191
Query: 187 GTRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
GT + + + P + ++ + G + T +C G P P + W +
Sbjct: 3192 GTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRS- 3250
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
PL L+ +L + V D G+Y C A + G A+ L V PP P
Sbjct: 3251 ---PLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEH 3307
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+V++G + C A G P T WS G+ PG + + + F+ D+
Sbjct: 3308 ASVQAGETVQLQCLAHGTPPLTFQWSRVGSS---LPGRATAR-NELLHFERAAP---EDS 3360
Query: 362 DKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ R T + V+ G L TS P + P +T I + F
Sbjct: 3361 GRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFH 3420
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
C + W+ EG L H DG L +++LD+S GTY C A GK
Sbjct: 3421 CAVPSDQGTQLRWFKEGGQLPPGHS---VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQA 3477
Query: 479 SGALLVDS 486
S L++ +
Sbjct: 3478 SAQLVIQA 3485
Score = 118 bits (283), Expect = 2e-25
Identities = 119/479 (24%), Positives = 182/479 (37%), Gaps = 38/479 (7%)
Query: 8 SGEAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ +AP ++E P V + +L C+ GSP W + V + L
Sbjct: 1672 TNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSEL 1731
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GD 123
F SDAGVY C N + + SR L + + E ++S G
Sbjct: 1732 HFPSVQP----SDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGA 1787
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIA 182
V C SP + W T L +G +D G L I++ + +DAG Y C
Sbjct: 1788 DVTFICTAKSKSPAYTLVW-----TRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTG 1842
Query: 183 RNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
N + ATL + P + P + Q G F+C G P P + W
Sbjct: 1843 SNMF-AMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-T 1900
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--DPPSI 295
GG +P + ++ G LRL V D+ +Y C A +S G A L V+ P +
Sbjct: 1901 GGPGGQLP-AKAQI-HGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+SP V +G R C A G P T+ W EG P +R + A + +
Sbjct: 1959 QVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGS---LPPQARSERTDIAT---LLI 2012
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
I D +C A + AG++ R ++ V S D PP + S+ ++
Sbjct: 2013 PAITTAD----AGFYLCVATSPAGTAQARMQVVVLSASDASPPGVKIESSSPSVTEGQTL 2068
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C + + WY G +L + + + L L + +DSG Y C + G
Sbjct: 2069 DLNCVVAGSAHAQVTWYRRGGSLPPHTQ---VHGSRLRLPQVSPADSGEYVCRVENGSG 2124
Score = 105 bits (253), Expect = 7e-22
Identities = 127/481 (26%), Positives = 182/481 (37%), Gaps = 50/481 (10%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + P +TV Q A C A GSP+P + W GG I GG+ L
Sbjct: 1865 APVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-TGGPGGQLPAKAQI--HGGILRLP 1921
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLEC 129
A +D Y C A +S G +R A LHV ++ PE Q G TV L C
Sbjct: 1922 AVE---PTDQAQYLCRAHSSAGQQVAR-AVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC 1977
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G P + W+K G +L +R D L+I DAG Y C+A + AGT
Sbjct: 1978 -RAAGVPSATITWRKEGGSL--PPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTA 2034
Query: 190 ESAIATLKIHIK----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
++ + + + P + G ++ C V G V W R GG++P
Sbjct: 2035 QARMQVVVLSASDASPPGVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRR--GGSLP 2092
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----YDPPS------- 294
+V LRL V AD GEY C EN G AS ++V + PS
Sbjct: 2093 -PHTQV-HGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGS 2150
Query: 295 ---INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
I + P+S +V G C G+ + W G P +R + H
Sbjct: 2151 TRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGS---LP--ARHQTHG----- 2200
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLP 410
++L ++ DS VC V +G +T+ S P P + S+ T+
Sbjct: 2201 --SLLRLHQVTPADS-GEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVA 2257
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
C + WY G +L H+ L + +D+G Y C AS
Sbjct: 2258 EGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQ---VRGSRLYIFQASPADAGQYVCRAS 2314
Query: 471 S 471
+
Sbjct: 2315 N 2315
Score = 103 bits (246), Expect = 5e-21
Identities = 125/496 (25%), Positives = 194/496 (39%), Gaps = 64/496 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V G P + + TVA Q L+C G + WYK G + + R +
Sbjct: 2239 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA---RHQVRGSR 2295
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-------LHVAVLREEFRLEPESKQ 118
L+ +A+ +DAG Y C A+N + + T + A + R+EP S Q
Sbjct: 2296 LYIFQASP----ADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQ 2351
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
A+G T+ L C+ P G V W K G +L H G L + A D+G Y
Sbjct: 2352 VAEGQTLDLNCVVP-GQSHAQVTWHKRGGSL-----PVRHQTHGSLLRLYQASPADSGEY 2405
Query: 179 QC-IARNAAGTRESAIATLK-------IHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDP 229
C + ++ S + T++ + + P + I VA+ G ++ C V G
Sbjct: 2406 VCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAE-GQTLDLNCLVAGQA 2464
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
V W + GG++P R +V LRL V AD GEY C S G AS +T+
Sbjct: 2465 HAQVTWHKR--GGSLP-ARHQV-HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTI 2520
Query: 290 YDPPS----------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG----NRTII 335
S + + +S ++ +G+ C + T+ W G +R I
Sbjct: 2521 QQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI 2580
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
R T G V + ++ SR T + + +GSS V +
Sbjct: 2581 VGSRLRIP-QVTPADSGEYVCHV--SNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESS 2637
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
P ++ QTL + C P+ II WY G +L H+ T+ L L
Sbjct: 2638 SPTVV----EGQTLDLN------CVVARQPQAIITWYKRGGSLPSRHQ---THGSHLRLH 2684
Query: 456 DLDKSDSGTYTCVASS 471
+ +DSG Y C A++
Sbjct: 2685 QMSVADSGEYVCRANN 2700
Score = 96.3 bits (229), Expect = 6e-19
Identities = 126/512 (24%), Positives = 193/512 (37%), Gaps = 60/512 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + + VA Q LNC G + W+K G + + R + L
Sbjct: 2434 GVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPA---RHQVHGSRLRL 2490
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARS--------RNATLHVAVLREEFRLEPESKQSA 120
L+ T +D+G Y C S GT + R + H + R+E S A
Sbjct: 2491 LQVTP----ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLA 2546
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T+ L CL +P + W K G +L SR H + G L I D+G Y C
Sbjct: 2547 NGHTLDLNCLVASQAPH-TITWYKRGGSL----PSR-HQIVGSRLRIPQVTPADSGEYVC 2600
Query: 181 IARNAAGTRE-SAIATLK----IHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
N AG+RE S I T++ H+ P I V + G ++ C V P
Sbjct: 2601 HVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVE-GQTLDLNCVVARQPQA 2659
Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-- 289
+ W + GG++P R + LRL + +AD GEY C A N++ A+ AS ++V
Sbjct: 2660 IITWYKR--GGSLP-SRHQT-HGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSP 2715
Query: 290 -YDPPS-------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PG 338
PS I + +S +V G C G+ + W G G
Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRG 2775
Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
+H + G V + + + +V + +GSS V + R P
Sbjct: 2776 SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLV--TIEASGSSAVHVPAPGGAPPIRIEP 2833
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ QTL +K C + W+ G L H+ + L L +
Sbjct: 2834 SSSRVAEGQTLDLK------CVVPGQAHAQVTWHKRGGNLPARHQ---VHGPLLRLNQVS 2884
Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+DSG Y+C + G + + L+ P +P
Sbjct: 2885 PADSGEYSCQVTGSSGT-LEASVLVTIEPSSP 2915
Score = 94.3 bits (224), Expect = 2e-18
Identities = 134/512 (26%), Positives = 193/512 (37%), Gaps = 79/512 (15%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILP 62
+V S P IE TV Q LNC P I WYK G + S TH S L
Sbjct: 2624 HVPSVSPPIRIESS-SPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHL- 2681
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE---------FRLE 113
H +D+G Y C A N+ A + + V+ R+E
Sbjct: 2682 --------RLHQMSVADSGEYVCRANNNID-ALEASIVISVSPSAGSPSAPGSSMPIRIE 2732
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
S A+G+T+ L C+ P G V W K G +L H G L +
Sbjct: 2733 SSSSHVAEGETLDLNCVVP-GQAHAQVTWHKRGGSL-----PSHHQTRGSRLRLHHVSPA 2786
Query: 174 DAGRYQCIARNAAGTRE-SAIATLK------IHIK-----PYLITGPEDVVAQTGSSVTF 221
D+G Y C ++G E S + T++ +H+ P + P G ++
Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDL 2846
Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
+C V G V W + GGN+P R +V LRL+ V AD GEYSC+ S G +
Sbjct: 2847 KCVVPGQAHAQVTWHKR--GGNLP-ARHQV-HGPLLRLNQVSPADSGEYSCQVTGSSGTL 2902
Query: 282 SASGYLTVYDPPS------------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
AS +T+ +P S I + +S +V G C G+ + W
Sbjct: 2903 EASVLVTI-EPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR 2961
Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
G P +R + H + L ++ DS VC A + G TV
Sbjct: 2962 GGS---LP--ARHQTHGSQ-------LRLHLVSPADS-GEYVCRAASGPGPE-QEASFTV 3007
Query: 390 T------SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNH 442
T S P+I+ P + T+ A F C PI + W + L N
Sbjct: 3008 TVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNV 3067
Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+ N + + S+ GTY CVAS+ +G
Sbjct: 3068 HIS-PNGSIITIVGTRPSNHGTYRCVASNAYG 3098
Score = 94.3 bits (224), Expect = 2e-18
Identities = 82/286 (28%), Positives = 120/286 (41%), Gaps = 23/286 (8%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAG 64
+ +G P + P T + +C +RW+K GG L + +
Sbjct: 3394 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDQGTQLRWFKEGGQLPPGHSVQD----- 3448
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G+ ++ S G Y C+A +G A++ + A+ + + G
Sbjct: 3449 GVLRIQNLD---QSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHA 3505
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
V ECL G P+P V W K G G R +V G +V I DAG+Y+C A
Sbjct: 3506 VEFECLA-LGDPKPQVTWSKVG------GHLRPGIVQSGGVVRIAHVELADAGQYRCTAT 3558
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
NAAGT +S + L + P I+ P++V GS+ F C G P PD+ W + G
Sbjct: 3559 NAAGTTQSHVLLL-VQALPQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSK-LDGSL 3615
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
P R L++ L L +V D G Y C A N G V A +L V
Sbjct: 3616 PPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3658
Score = 93.5 bits (222), Expect = 4e-18
Identities = 90/350 (25%), Positives = 136/350 (38%), Gaps = 40/350 (11%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
+V G P + P V + L CRA G PS I W K G +
Sbjct: 1949 HVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIA 2008
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE---FRLEPESKQSAQ 121
L T +DAG Y C AT+ GTA++R + ++ ++E S +
Sbjct: 2009 TLLIPAIT----TADAGFYLCVATSPAGTAQARMQVVVLSASDASPPGVKIESSSPSVTE 2064
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G T+ L C+ GS V W + G +L +++H G L + D+G Y C
Sbjct: 2065 GQTLDLNCV-VAGSAHAQVTWYRRGGSL--PPHTQVH---GSRLRLPQVSPADSGEYVCR 2118
Query: 182 ARNAAGTRESAIATLKIH--------------IKPYLITGPEDVVAQTGSSVTFQCRVGG 227
N +G +E++I +H +P I VA+ G ++ C V G
Sbjct: 2119 VENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAE-GQTLDLNCVVPG 2177
Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGY 286
V W + GG++P + GS LRL V AD GEY C + G + AS
Sbjct: 2178 QAHAQVTWHKR--GGSLP---ARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVL 2232
Query: 287 LTVYDP------PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
+T+ P + + +S V G +C G+ + W G
Sbjct: 2233 VTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG 2282
Score = 82.6 bits (195), Expect = 8e-15
Identities = 117/500 (23%), Positives = 180/500 (36%), Gaps = 69/500 (13%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA + LNC G + W+K G + S H++ G L H +D+G
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSH-HQT---RGSRLRL---HHVSPADSGE 2790
Query: 83 YWCEATNSYGTAR---------SRNATLHVAVL--REEFRLEPESKQSAQGDTVVLECLP 131
Y C S G S ++ +HV R+EP S + A+G T+ L+C+
Sbjct: 2791 YVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVV 2850
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
P G V W K G L H V G L + D+G Y C ++GT E+
Sbjct: 2851 P-GQAHAQVTWHKRGGNL-----PARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2904
Query: 192 AIATLKIHIKPYLITGP---EDVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGG 241
++ P I P + + + SS + C V G V W + G
Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR--G 2962
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--------- 292
G++P LRL V AD GEY C A + G + + P
Sbjct: 2963 GSLPARHQT--HGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLR 3020
Query: 293 -PSINLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVF 350
P I++ P S V+ G A F C P ++ W D H +
Sbjct: 3021 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQEL-------EDNVH---IS 3070
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-L 409
+++TI T + + T C A N G + L+V PP ++ P +
Sbjct: 3071 PNGSIITIVGT-RPSNHGTYRCVASNAYGVAQSVVNLSV-----HGPPTVSVLPEGPVWV 3124
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYT 466
+ C + P W + +R + + L + SD+GTY
Sbjct: 3125 KVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYV 3184
Query: 467 CVASSRHGKYVWSGALLVDS 486
C+A + G ++VD+
Sbjct: 3185 CLAQNALGTAQKQVEVIVDT 3204
Score = 70.1 bits (164), Expect = 4e-11
Identities = 73/291 (25%), Positives = 115/291 (39%), Gaps = 21/291 (7%)
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
P + G S + +C+V G P W R G +P G + L +V +D
Sbjct: 1683 PARSIVPQGGSHSLRCQVSGSPPHYFYWSRE-DGRPVPSGTQQRHQGSELHFPSVQPSDA 1741
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLS-----PNSVNVESGNVARFTCTATGR-PE 321
G Y C N + ++ L V + PS ++ S +V G F CTA + P
Sbjct: 1742 GVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPA 1801
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
T+ W+ N + P + D F+G +LTI + +D+ T VC+ N
Sbjct: 1802 YTLVWTRLHNGKL--PTRAMD-------FNG--ILTIRNVQLSDA-GTYVCTGSNMFAMD 1849
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
L V + P+++ P T+ +A F C+A +P P + W G Q
Sbjct: 1850 QGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW--TGGPGGQL 1907
Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+ + G L L ++ +D Y C A S G+ V L V P +
Sbjct: 1908 PAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TL 452
PP + P + V F C AI P PII W + + R VT++G TL
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464
Query: 453 VLKDLDKSDSGTYTCVASSRHG 474
+++D+ +SD G YTC A + G
Sbjct: 465 IIRDVKESDQGAYTCEAMNARG 486
Score = 48.4 bits (110), Expect = 2e-04
Identities = 32/85 (37%), Positives = 47/85 (55%), Gaps = 7/85 (8%)
Query: 202 PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDD---GS 256
P ++T P E + A G +VTF C G P P + WR G++P RV V + G+
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWR--LNWGHIPSHPRVTVTSEGGRGT 463
Query: 257 LRLDNVILADEGEYSCEAENSVGAV 281
L + +V +D+G Y+CEA N+ G V
Sbjct: 464 LIIRDVKESDQGAYTCEAMNARGMV 488
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQT 173
ES Q+++G TV C+ G P P + W+ N + + G G L+I+D +++
Sbjct: 414 ESIQASRGQTVTFTCVAI-GVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKES 472
Query: 174 DAGRYQCIARNAAG 187
D G Y C A NA G
Sbjct: 473 DQGAYTCEAMNARG 486
Score = 39.5 bits (88), Expect = 0.072
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 12 PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P ++ P + + +R Q T C A G P+P I W + S ++ GG L
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLI 465
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
+ SD G Y CEA N+ G
Sbjct: 466 IRDVK-ESDQGAYTCEAMNARG 486
Score = 33.5 bits (73), Expect = 4.7
Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 8/92 (8%)
Query: 292 PPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
PP + P S+ G FTC A G P P + W + P ++
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVT------VTSE 458
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
G L I D ++D + C A+N G F
Sbjct: 459 GGRGTLIIRDVKESD-QGAYTCEAMNARGMVF 489
>M77640-1|AAC14352.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 143 bits (347), Expect = 3e-33
Identities = 136/484 (28%), Positives = 202/484 (41%), Gaps = 37/484 (7%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAG 64
E P I EQ P + V +L C A G P RW + GV + P
Sbjct: 33 EPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHS 92
Query: 65 GLFFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G F + + G+Y C A+N GTA S L + + + + +G+
Sbjct: 93 GSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 152
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIA 182
+VVL C PP + +YW N + L D R+ + GNL + +D Y C A
Sbjct: 153 SVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA 211
Query: 183 RNAAGTR-----ESAIATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDP 229
+ GTR E +K I KP L+ +VA G + +C G P
Sbjct: 212 -HFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
P + W R +G MP RV + +L+L V D+GEY C AENS+G+ + Y+T
Sbjct: 271 TPTIKWLRPSGP--MPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 328
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
V P P S G AR C GRP+P + W + G I +++D+ +
Sbjct: 329 VEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--R 383
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
+ G +L ++ +D+ T C A N G + V P I+T
Sbjct: 384 IQRGALIL--SNVQPSDTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYM 437
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
S A C A P P + W E G ++Q+ R +GTL ++DL +D+G Y C
Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 497
Query: 468 VASS 471
+A++
Sbjct: 498 LAAN 501
Score = 127 bits (306), Expect = 3e-28
Identities = 159/609 (26%), Positives = 239/609 (39%), Gaps = 71/609 (11%)
Query: 21 VTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGG-LFFLRATHGRVHS 78
V V + L C S P I W +L + R + G L+F HS
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHS 205
Query: 79 DAGVYWCEA--TNSYGTARSRNATLHVAVL-----REEFRLEPESKQS----AQGDTVVL 127
D Y C A + + L V R+ L P + S QG +VL
Sbjct: 206 D---YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 262
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
EC+ G P P + W + + D + L + + D G Y+C+A N+ G
Sbjct: 263 ECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLG 319
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPL 246
+ A + + PY + P+ + G + C+V G P P+V WR +
Sbjct: 320 SARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK 378
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
+ + G+L L NV +D CEA N G + A+ Y+ V P+ L+ ++ +
Sbjct: 379 DQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMA 438
Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G+ A C A G P P++ W E T++ +++ A +G L I D N
Sbjct: 439 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LGIRDLQAN 490
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ C A N + + L V IT GP + S F C A
Sbjct: 491 DT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTFTCQASFD 544
Query: 425 P--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 545 PSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRA 604
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILG 537
LLV V S PGP + + H +T + V +SWS ++ I
Sbjct: 605 QLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED-HNAPIEK 647
Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
Y +E +E P W + + +QT +K L P + Y F V N +G
Sbjct: 648 YDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPG 698
Query: 597 GPSPVSDSV 605
PSPVS++V
Sbjct: 699 EPSPVSETV 707
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 326 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 385
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 386 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 440
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 441 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 497
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 498 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 555
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 556 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 612
Score = 40.7 bits (91), Expect = 0.031
Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+++ + YE + + +G + + +D P P + ILN++ V +KW
Sbjct: 775 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 834
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-----QATSLIMTNLTSGVSYSV 808
P +L G + GYNV W + K H TS+I++ L SY +
Sbjct: 835 PVDLAQVKGHLRGYNVTY-WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 893
Query: 809 QIAAETIIGLGPFSQ 823
++ A G GP S+
Sbjct: 894 EVQAFNGRGSGPASE 908
>M74387-1|AAA59476.1| 1253|Homo sapiens cell adhesion molecule L1
protein.
Length = 1253
Score = 143 bits (347), Expect = 3e-33
Identities = 136/484 (28%), Positives = 202/484 (41%), Gaps = 37/484 (7%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAG 64
E P I EQ P + V +L C A G P RW + GV + P
Sbjct: 33 EPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHS 92
Query: 65 GLFFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G F + + G+Y C A+N GTA S L + + + + +G+
Sbjct: 93 GSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 152
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIA 182
+VVL C PP + +YW N + L D R+ + GNL + +D Y C A
Sbjct: 153 SVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA 211
Query: 183 RNAAGTR-----ESAIATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDP 229
+ GTR E +K I KP L+ +VA G + +C G P
Sbjct: 212 -HFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
P + W R +G MP RV + +L+L V D+GEY C AENS+G+ + Y+T
Sbjct: 271 TPTIKWLRPSGP--MPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 328
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
V P P S G AR C GRP+P + W + G I +++D+ +
Sbjct: 329 VEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--R 383
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
+ G +L ++ +D+ T C A N G + V P I+T
Sbjct: 384 IQRGALIL--SNVQPSDTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYM 437
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
S A C A P P + W E G ++Q+ R +GTL ++DL +D+G Y C
Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 497
Query: 468 VASS 471
+A++
Sbjct: 498 LAAN 501
Score = 127 bits (306), Expect = 3e-28
Identities = 159/609 (26%), Positives = 239/609 (39%), Gaps = 71/609 (11%)
Query: 21 VTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGG-LFFLRATHGRVHS 78
V V + L C S P I W +L + R + G L+F HS
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHS 205
Query: 79 DAGVYWCEA--TNSYGTARSRNATLHVAVL-----REEFRLEPESKQS----AQGDTVVL 127
D Y C A + + L V R+ L P + S QG +VL
Sbjct: 206 D---YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 262
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
EC+ G P P + W + + D + L + + D G Y+C+A N+ G
Sbjct: 263 ECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLG 319
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPL 246
+ A + + PY + P+ + G + C+V G P P+V WR +
Sbjct: 320 SARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK 378
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
+ + G+L L NV +D CEA N G + A+ Y+ V P+ L+ ++ +
Sbjct: 379 DQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMA 438
Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G+ A C A G P P++ W E T++ +++ A +G L I D N
Sbjct: 439 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LGIRDLQAN 490
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ C A N + + L V IT GP + S F C A
Sbjct: 491 DT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTFTCQASFD 544
Query: 425 P--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 545 PSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRA 604
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILG 537
LLV V S PGP + + H +T + V +SWS ++ I
Sbjct: 605 QLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED-HNAPIEK 647
Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
Y +E +E P W + + +QT +K L P + Y F V N +G
Sbjct: 648 YDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPG 698
Query: 597 GPSPVSDSV 605
PSPVS++V
Sbjct: 699 EPSPVSETV 707
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 326 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 385
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 386 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 440
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 441 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 497
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 498 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 555
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 556 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 612
Score = 40.7 bits (91), Expect = 0.031
Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+++ + YE + + +G + + +D P P + ILN++ V +KW
Sbjct: 775 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 834
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-----QATSLIMTNLTSGVSYSV 808
P +L G + GYNV W + K H TS+I++ L SY +
Sbjct: 835 PVDLAQVKGHLRGYNVTY-WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 893
Query: 809 QIAAETIIGLGPFSQ 823
++ A G GP S+
Sbjct: 894 EVQAFNGRGSGPASE 908
>BC126229-1|AAI26230.1| 1257|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1257
Score = 143 bits (347), Expect = 3e-33
Identities = 136/484 (28%), Positives = 202/484 (41%), Gaps = 37/484 (7%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAG 64
E P I EQ P + V +L C A G P RW + GV + P
Sbjct: 33 EPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHS 92
Query: 65 GLFFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G F + + G+Y C A+N GTA S L + + + + +G+
Sbjct: 93 GSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 152
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIA 182
+VVL C PP + +YW N + L D R+ + GNL + +D Y C A
Sbjct: 153 SVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA 211
Query: 183 RNAAGTR-----ESAIATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDP 229
+ GTR E +K I KP L+ +VA G + +C G P
Sbjct: 212 -HFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
P + W R +G MP RV + +L+L V D+GEY C AENS+G+ + Y+T
Sbjct: 271 TPTIKWLRPSGP--MPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 328
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
V P P S G AR C GRP+P + W + G I +++D+ +
Sbjct: 329 VEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--R 383
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
+ G +L ++ +D+ T C A N G + V P I+T
Sbjct: 384 IQRGALIL--SNVQPSDTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYM 437
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
S A C A P P + W E G ++Q+ R +GTL ++DL +D+G Y C
Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 497
Query: 468 VASS 471
+A++
Sbjct: 498 LAAN 501
Score = 127 bits (306), Expect = 3e-28
Identities = 159/609 (26%), Positives = 239/609 (39%), Gaps = 71/609 (11%)
Query: 21 VTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGG-LFFLRATHGRVHS 78
V V + L C S P I W +L + R + G L+F HS
Sbjct: 146 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHS 205
Query: 79 DAGVYWCEA--TNSYGTARSRNATLHVAVL-----REEFRLEPESKQS----AQGDTVVL 127
D Y C A + + L V R+ L P + S QG +VL
Sbjct: 206 D---YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 262
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
EC+ G P P + W + + D + L + + D G Y+C+A N+ G
Sbjct: 263 ECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLG 319
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPL 246
+ A + + PY + P+ + G + C+V G P P+V WR +
Sbjct: 320 SARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK 378
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
+ + G+L L NV +D CEA N G + A+ Y+ V P+ L+ ++ +
Sbjct: 379 DQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMA 438
Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G+ A C A G P P++ W E T++ +++ A +G L I D N
Sbjct: 439 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LGIRDLQAN 490
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ C A N + + L V IT GP + S F C A
Sbjct: 491 DT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTFTCQASFD 544
Query: 425 P--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 545 PSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRA 604
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILG 537
LLV V S PGP + + H +T + V +SWS ++ I
Sbjct: 605 QLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED-HNAPIEK 647
Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
Y +E +E P W + + +QT +K L P + Y F V N +G
Sbjct: 648 YDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPG 698
Query: 597 GPSPVSDSV 605
PSPVS++V
Sbjct: 699 EPSPVSETV 707
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 326 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 385
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 386 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 440
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 441 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 497
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 498 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 555
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 556 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 612
Score = 40.7 bits (91), Expect = 0.031
Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+++ + YE + + +G + + +D P P + ILN++ V +KW
Sbjct: 775 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 834
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-----QATSLIMTNLTSGVSYSV 808
P +L G + GYNV W + K H TS+I++ L SY +
Sbjct: 835 PVDLAQVKGHLRGYNVTY-WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 893
Query: 809 QIAAETIIGLGPFSQ 823
++ A G GP S+
Sbjct: 894 EVQAFNGRGSGPASE 908
>AK027852-1|BAB55411.1| 792|Homo sapiens protein ( Homo sapiens
cDNA FLJ14946 fis, clone PLACE2000034, weakly similar to
LAR PROTEIN PRECURSOR (EC 3.1.3.48). ).
Length = 792
Score = 143 bits (347), Expect = 3e-33
Identities = 85/212 (40%), Positives = 114/212 (53%), Gaps = 14/212 (6%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLFF 68
P I+ P D PA ++C+A G P P IRW G +V D H +LP G L
Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHH-LLPDGTLLL 90
Query: 69 LRA-THGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L+ G H +D GVY CEA+N GTA SR A L VAVLRE+F+++P +
Sbjct: 91 LQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVV 150
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ LEC PP G PEP V W K+ + L H V GG+L++ A ++D G Y C+
Sbjct: 151 GEQFTLECGPPWGHPEPTVSWWKDEKPLAL--QPGRHTVSGGSLLMARAEKSDEGTYMCV 208
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
A N+AG RES A + I +P T P +++A
Sbjct: 209 ATNSAGHRESRAARVSIQ-EPQDYTEPVELLA 239
Score = 57.6 bits (133), Expect = 3e-07
Identities = 49/196 (25%), Positives = 83/196 (42%), Gaps = 25/196 (12%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP I + P + AR +C A+G+P PT+ W + G + P D +H D
Sbjct: 31 PPQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPP---DPHHLLP--D 85
Query: 352 GVTVLTINDTDKNDSRN---------TIVCSAVNYAGSSFVRG---KLTVTSDDDRPPPI 399
G T+L + + + + C A N G++ RG + V +D + P
Sbjct: 86 G-TLLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQP- 143
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICT-PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ + C PEP ++W+ + + L R+ + G+L++ +
Sbjct: 144 -----RDMVAVVGEQFTLECGPPWGHPEPTVSWWKDEKPLALQPGRHTVSGGSLLMARAE 198
Query: 459 KSDSGTYTCVASSRHG 474
KSD GTY CVA++ G
Sbjct: 199 KSDEGTYMCVATNSAG 214
Score = 54.0 bits (124), Expect = 3e-06
Identities = 46/134 (34%), Positives = 61/134 (45%), Gaps = 8/134 (5%)
Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
E+ L YEF + P + G SN + + + VP PP + + N T V + W
Sbjct: 309 ELGGLHWGQDYEFKVRPSSGRARGPDSNVLLLRLPEKVPSAPPQEVTLKPGNGT-VFVSW 367
Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN-TTVHQATSLIMTNLTSGVSYSVQIA 811
PP + NGII GY V W N S+ N T V + T L + G SY VQ+A
Sbjct: 368 VPPPAENHNGIIRGYQV---W--SLGNTSLPPANWTVVGEQTQLEIATHMPG-SYCVQVA 421
Query: 812 AETIIGLGPFSQKV 825
A T G G S+ V
Sbjct: 422 AVTGAGAGEPSRPV 435
Score = 48.0 bits (109), Expect = 2e-04
Identities = 54/214 (25%), Positives = 84/214 (39%), Gaps = 26/214 (12%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM-PLGRVKVLDDGSLRL- 259
P ++ P+D + Q C+ G P P + W + +M P +L DG+L L
Sbjct: 32 PQILVHPQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGTLLLL 91
Query: 260 ----------DNVILADEGEYSCEAENSVG-AVSASGYLTV-YDPPSINLSPNSVNVESG 307
+ D G Y+CEA N +G AVS L+V + P + G
Sbjct: 92 QPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARLSVAVLREDFQIQPRDMVAVVG 151
Query: 308 NVARFTC-TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
C G PEPT+ W + + PG H + G ++L +K+D
Sbjct: 152 EQFTLECGPPWGHPEPTVSWWKDEKPLALQPGR-----HTVS---GGSLLMAR-AEKSD- 201
Query: 367 RNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
T +C A N AG R ++++ D P+
Sbjct: 202 EGTYMCVATNSAGHRESRAARVSIQEPQDYTEPV 235
Score = 39.5 bits (88), Expect = 0.072
Identities = 33/103 (32%), Positives = 43/103 (41%), Gaps = 14/103 (13%)
Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL--IQNHRRNVTNDGT 451
D PP I+ + P +Q A C A P P I W G+ L + ++ DGT
Sbjct: 29 DSPPQILVH-PQDQLFQGPGPARMSCQASGQPPPTIRWLLNGQPLSMVPPDPHHLLPDGT 87
Query: 452 LVLKDLD-----------KSDSGTYTCVASSRHGKYVWSGALL 483
L+L +D G YTC AS+R G V GA L
Sbjct: 88 LLLLQPPARGHAHDGQALSTDLGVYTCEASNRLGTAVSRGARL 130
>AB102653-1|BAC81122.1| 1255|Homo sapiens L1 cell adhesion molecule
protein.
Length = 1255
Score = 143 bits (347), Expect = 3e-33
Identities = 136/484 (28%), Positives = 202/484 (41%), Gaps = 37/484 (7%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAG 64
E P I EQ P + V +L C A G P RW + GV + P
Sbjct: 31 EPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHS 90
Query: 65 GLFFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G F + + G+Y C A+N GTA S L + + + + +G+
Sbjct: 91 GSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 150
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIA 182
+VVL C PP + +YW N + L D R+ + GNL + +D Y C A
Sbjct: 151 SVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA 209
Query: 183 RNAAGTR-----ESAIATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDP 229
+ GTR E +K I KP L+ +VA G + +C G P
Sbjct: 210 -HFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 268
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
P + W R +G MP RV + +L+L V D+GEY C AENS+G+ + Y+T
Sbjct: 269 TPTIKWLRPSGP--MPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 326
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
V P P S G AR C GRP+P + W + G I +++D+ +
Sbjct: 327 VEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--R 381
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
+ G +L ++ +D+ T C A N G + V P I+T
Sbjct: 382 IQRGALIL--SNVQPSDTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYM 435
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
S A C A P P + W E G ++Q+ R +GTL ++DL +D+G Y C
Sbjct: 436 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 495
Query: 468 VASS 471
+A++
Sbjct: 496 LAAN 499
Score = 127 bits (306), Expect = 3e-28
Identities = 159/609 (26%), Positives = 239/609 (39%), Gaps = 71/609 (11%)
Query: 21 VTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGG-LFFLRATHGRVHS 78
V V + L C S P I W +L + R + G L+F HS
Sbjct: 144 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHS 203
Query: 79 DAGVYWCEA--TNSYGTARSRNATLHVAVL-----REEFRLEPESKQS----AQGDTVVL 127
D Y C A + + L V R+ L P + S QG +VL
Sbjct: 204 D---YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 260
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
EC+ G P P + W + + D + L + + D G Y+C+A N+ G
Sbjct: 261 ECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLG 317
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPL 246
+ A + + PY + P+ + G + C+V G P P+V WR +
Sbjct: 318 SARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK 376
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
+ + G+L L NV +D CEA N G + A+ Y+ V P+ L+ ++ +
Sbjct: 377 DQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMA 436
Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G+ A C A G P P++ W E T++ +++ A +G L I D N
Sbjct: 437 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LGIRDLQAN 488
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ C A N + + L V IT GP + S F C A
Sbjct: 489 DT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTFTCQASFD 542
Query: 425 P--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 543 PSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRA 602
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILG 537
LLV V S PGP + + H +T + V +SWS ++ I
Sbjct: 603 QLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED-HNAPIEK 645
Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
Y +E +E P W + + +QT +K L P + Y F V N +G
Sbjct: 646 YDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPG 696
Query: 597 GPSPVSDSV 605
PSPVS++V
Sbjct: 697 EPSPVSETV 705
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 324 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 383
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 384 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 438
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 439 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 495
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 496 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 553
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 554 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 610
Score = 40.7 bits (91), Expect = 0.031
Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+++ + YE + + +G + + +D P P + ILN++ V +KW
Sbjct: 773 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 832
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-----QATSLIMTNLTSGVSYSV 808
P +L G + GYNV W + K H TS+I++ L SY +
Sbjct: 833 PVDLAQVKGHLRGYNVTY-WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 891
Query: 809 QIAAETIIGLGPFSQ 823
++ A G GP S+
Sbjct: 892 EVQAFNGRGSGPASE 906
>AL590556-2|CAH71870.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 143 bits (346), Expect = 4e-33
Identities = 151/515 (29%), Positives = 212/515 (41%), Gaps = 61/515 (11%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + + ++TV ATL C A GSP+P I W K + HR L L R
Sbjct: 3211 APQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQ-HR--LEGDTLIIPR 3267
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D+G Y C AT+ G A + LHV + PE G+TV L+CL
Sbjct: 3268 VAQ----QDSGQYICNATSPAGHAEA-TIILHVESPPYATTV-PEHASVQAGETVQLQCL 3321
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G+P W + G +L +R L L + A D+GRY+C N G+ E
Sbjct: 3322 A-HGTPPLTFQWSRVGSSLPGRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAE 3375
Query: 191 SAIATLKIHIKPYLITG--------------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
A A L + P + P+ G+SV F C V D + W
Sbjct: 3376 -AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWF 3434
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-- 294
+ GG +P G + DG LR+ N+ + +G Y C+A G AS L + PS
Sbjct: 3435 KE--GGQLPPGHS--VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL 3490
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
IN+ + V G+ F C A G P+P + WS G + PG+ + V
Sbjct: 3491 INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH--LRPGIVQSG-------GVVR 3541
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
+ + D R C+A N AG++ L V + P I + P +P S
Sbjct: 3542 IAHVELADAGQYR----CTATNAAGTTQSHVLLLVQA----LPQI--SMPQEVRVPAGSA 3591
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
AVFPC A P P I+W +L + R + L+L + D+GTY C A++R G
Sbjct: 3592 AVFPCIASGYPTPDISWSKLDGSLPPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQG 3648
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
K L V + P +F S LP P K
Sbjct: 3649 KVKAFAHLQVPERVVP---YFTQTPYSFLPLPTIK 3680
Score = 130 bits (313), Expect = 4e-29
Identities = 125/488 (25%), Positives = 192/488 (39%), Gaps = 35/488 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+P I P TV + Q A+ C +P ++ W + + H I P G + +
Sbjct: 3021 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVH--ISPNGSIITI 3078
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
T H G Y C A+N+YG A+S N ++H + PE + G V L
Sbjct: 3079 VGTRPSNH---GTYRCVASNAYGVAQSVVNLSVHGP---PTVSVLPEGPVWVKVGKAVTL 3132
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
EC+ G P + W + T L+D L I A+ +DAG Y C+A+NA
Sbjct: 3133 ECVSA-GEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNAL 3191
Query: 187 GTRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
GT + + + P + ++ + G + T +C G P P + W +
Sbjct: 3192 GTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRS- 3250
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
PL L+ +L + V D G+Y C A + G A+ L V PP P
Sbjct: 3251 ---PLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEH 3307
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+V++G + C A G P T WS G+ PG + + + F+ D+
Sbjct: 3308 ASVQAGETVQLQCLAHGTPPLTFQWSRVGSS---LPGRATAR-NELLHFERAAP---EDS 3360
Query: 362 DKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ R T + V+ G L TS P + P +T I + F
Sbjct: 3361 GRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFH 3420
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
C + W+ EG L H DG L +++LD+S GTY C A GK
Sbjct: 3421 CAVPSDRGTQLRWFKEGGQLPPGHS---VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQA 3477
Query: 479 SGALLVDS 486
S L++ +
Sbjct: 3478 SAQLVIQA 3485
Score = 118 bits (283), Expect = 2e-25
Identities = 119/479 (24%), Positives = 182/479 (37%), Gaps = 38/479 (7%)
Query: 8 SGEAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ +AP ++E P V + +L C+ GSP W + V + L
Sbjct: 1672 TNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSEL 1731
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GD 123
F SDAGVY C N + + SR L + + E ++S G
Sbjct: 1732 HFPSVQP----SDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGA 1787
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIA 182
V C SP + W T L +G +D G L I++ + +DAG Y C
Sbjct: 1788 DVTFICTAKSKSPAYTLVW-----TRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTG 1842
Query: 183 RNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
N + ATL + P + P + Q G F+C G P P + W
Sbjct: 1843 SNMF-AMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-T 1900
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--DPPSI 295
GG +P + ++ G LRL V D+ +Y C A +S G A L V+ P +
Sbjct: 1901 GGPGGQLP-AKAQI-HGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+SP V +G R C A G P T+ W EG P +R + A + +
Sbjct: 1959 QVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGS---LPPQARSERTDIAT---LLI 2012
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
I D +C A + AG++ R ++ V S D PP + S+ ++
Sbjct: 2013 PAITTAD----AGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2068
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C + + WY G +L + + + L L + +DSG Y C + G
Sbjct: 2069 DLNCVVAGSAHAQVTWYRRGGSLPPHTQ---VHGSRLRLPQVSPADSGEYVCRVENGSG 2124
Score = 108 bits (260), Expect = 1e-22
Identities = 130/482 (26%), Positives = 184/482 (38%), Gaps = 52/482 (10%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + P +TV Q A C A GSP+P + W GG I GG+ L
Sbjct: 1865 APVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-TGGPGGQLPAKAQI--HGGILRLP 1921
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLEC 129
A +D Y C A +S G +R A LHV ++ PE Q G TV L C
Sbjct: 1922 AVE---PTDQAQYLCRAHSSAGQQVAR-AVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC 1977
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G P + W+K G +L +R D L+I DAG Y C+A + AGT
Sbjct: 1978 -RAAGVPSATITWRKEGGSL--PPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTA 2034
Query: 190 ESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
++ I + + P I V + G ++ C V G V W R GG++
Sbjct: 2035 QARIQVVVLSASDASPPPVKIESSSPSVTE-GQTLDLNCVVAGSAHAQVTWYRR--GGSL 2091
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----YDPPS------ 294
P +V LRL V AD GEY C EN G AS ++V + PS
Sbjct: 2092 P-PHTQV-HGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPG 2149
Query: 295 ----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
I + P+S +V G C G+ + W G P +R + H
Sbjct: 2150 STRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGS---LP--ARHQTHG---- 2200
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTL 409
++L ++ DS VC V +G +T+ S P P + S+ T+
Sbjct: 2201 ---SLLRLHQVTPADS-GEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTV 2256
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
C + WY G +L H+ L + +D+G Y C A
Sbjct: 2257 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQ---VRGSRLYIFQASPADAGQYVCRA 2313
Query: 470 SS 471
S+
Sbjct: 2314 SN 2315
Score = 103 bits (246), Expect = 5e-21
Identities = 125/496 (25%), Positives = 194/496 (39%), Gaps = 64/496 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V G P + + TVA Q L+C G + WYK G + + R +
Sbjct: 2239 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA---RHQVRGSR 2295
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-------LHVAVLREEFRLEPESKQ 118
L+ +A+ +DAG Y C A+N + + T + A + R+EP S Q
Sbjct: 2296 LYIFQASP----ADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQ 2351
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
A+G T+ L C+ P G V W K G +L H G L + A D+G Y
Sbjct: 2352 VAEGQTLDLNCVVP-GQSHAQVTWHKRGGSL-----PVRHQTHGSLLRLYQASPADSGEY 2405
Query: 179 QC-IARNAAGTRESAIATLK-------IHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDP 229
C + ++ S + T++ + + P + I VA+ G ++ C V G
Sbjct: 2406 VCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAE-GQTLDLNCLVAGQA 2464
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
V W + GG++P R +V LRL V AD GEY C S G AS +T+
Sbjct: 2465 HAQVTWHKR--GGSLP-ARHQV-HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTI 2520
Query: 290 YDPPS----------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG----NRTII 335
S + + +S ++ +G+ C + T+ W G +R I
Sbjct: 2521 QQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI 2580
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
R T G V + ++ SR T + + +GSS V +
Sbjct: 2581 VGSRLRIP-QVTPADSGEYVCHV--SNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESS 2637
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
P ++ QTL + C P+ II WY G +L H+ T+ L L
Sbjct: 2638 SPTVV----EGQTLDLN------CVVARQPQAIITWYKRGGSLPSRHQ---THGSHLRLH 2684
Query: 456 DLDKSDSGTYTCVASS 471
+ +DSG Y C A++
Sbjct: 2685 QMSVADSGEYVCRANN 2700
Score = 96.3 bits (229), Expect = 6e-19
Identities = 126/512 (24%), Positives = 193/512 (37%), Gaps = 60/512 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + + VA Q LNC G + W+K G + + R + L
Sbjct: 2434 GVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPA---RHQVHGSRLRL 2490
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARS--------RNATLHVAVLREEFRLEPESKQSA 120
L+ T +D+G Y C S GT + R + H + R+E S A
Sbjct: 2491 LQVTP----ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLA 2546
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T+ L CL +P + W K G +L SR H + G L I D+G Y C
Sbjct: 2547 NGHTLDLNCLVASQAPH-TITWYKRGGSL----PSR-HQIVGSRLRIPQVTPADSGEYVC 2600
Query: 181 IARNAAGTRE-SAIATLK----IHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
N AG+RE S I T++ H+ P I V + G ++ C V P
Sbjct: 2601 HVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVE-GQTLDLNCVVARQPQA 2659
Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-- 289
+ W + GG++P R + LRL + +AD GEY C A N++ A+ AS ++V
Sbjct: 2660 IITWYKR--GGSLP-SRHQT-HGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSP 2715
Query: 290 -YDPPS-------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PG 338
PS I + +S +V G C G+ + W G G
Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRG 2775
Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
+H + G V + + + +V + +GSS V + R P
Sbjct: 2776 SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLV--TIEASGSSAVHVPAPGGAPPIRIEP 2833
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ QTL +K C + W+ G L H+ + L L +
Sbjct: 2834 SSSRVAEGQTLDLK------CVVPGQAHAQVTWHKRGGNLPARHQ---VHGPLLRLNQVS 2884
Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+DSG Y+C + G + + L+ P +P
Sbjct: 2885 PADSGEYSCQVTGSSGT-LEASVLVTIEPSSP 2915
Score = 94.3 bits (224), Expect = 2e-18
Identities = 134/512 (26%), Positives = 193/512 (37%), Gaps = 79/512 (15%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILP 62
+V S P IE TV Q LNC P I WYK G + S TH S L
Sbjct: 2624 HVPSVSPPIRIESS-SPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHL- 2681
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE---------FRLE 113
H +D+G Y C A N+ A + + V+ R+E
Sbjct: 2682 --------RLHQMSVADSGEYVCRANNNID-ALEASIVISVSPSAGSPSAPGSSMPIRIE 2732
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
S A+G+T+ L C+ P G V W K G +L H G L +
Sbjct: 2733 SSSSHVAEGETLDLNCVVP-GQAHAQVTWHKRGGSL-----PSHHQTRGSRLRLHHVSPA 2786
Query: 174 DAGRYQCIARNAAGTRE-SAIATLK------IHIK-----PYLITGPEDVVAQTGSSVTF 221
D+G Y C ++G E S + T++ +H+ P + P G ++
Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDL 2846
Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
+C V G V W + GGN+P R +V LRL+ V AD GEYSC+ S G +
Sbjct: 2847 KCVVPGQAHAQVTWHKR--GGNLP-ARHQV-HGPLLRLNQVSPADSGEYSCQVTGSSGTL 2902
Query: 282 SASGYLTVYDPPS------------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
AS +T+ +P S I + +S +V G C G+ + W
Sbjct: 2903 EASVLVTI-EPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR 2961
Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
G P +R + H + L ++ DS VC A + G TV
Sbjct: 2962 GGS---LP--ARHQTHGSQ-------LRLHLVSPADS-GEYVCRAASGPGPE-QEASFTV 3007
Query: 390 T------SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNH 442
T S P+I+ P + T+ A F C PI + W + L N
Sbjct: 3008 TVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNV 3067
Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+ N + + S+ GTY CVAS+ +G
Sbjct: 3068 HIS-PNGSIITIVGTRPSNHGTYRCVASNAYG 3098
Score = 93.9 bits (223), Expect = 3e-18
Identities = 82/286 (28%), Positives = 120/286 (41%), Gaps = 23/286 (8%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAG 64
+ +G P + P T + +C +RW+K GG L + +
Sbjct: 3394 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQD----- 3448
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G+ ++ S G Y C+A +G A++ + A+ + + G
Sbjct: 3449 GVLRIQNLD---QSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHA 3505
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
V ECL G P+P V W K G G R +V G +V I DAG+Y+C A
Sbjct: 3506 VEFECLA-LGDPKPQVTWSKVG------GHLRPGIVQSGGVVRIAHVELADAGQYRCTAT 3558
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
NAAGT +S + L + P I+ P++V GS+ F C G P PD+ W + G
Sbjct: 3559 NAAGTTQSHVLLL-VQALPQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSK-LDGSL 3615
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
P R L++ L L +V D G Y C A N G V A +L V
Sbjct: 3616 PPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3658
Score = 93.1 bits (221), Expect = 5e-18
Identities = 93/353 (26%), Positives = 137/353 (38%), Gaps = 46/353 (13%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
+V G P + P V + L CRA G PS I W K G +
Sbjct: 1949 HVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIA 2008
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQ 118
L T +DAG Y C AT+ GTA++R + V VL ++E S
Sbjct: 2009 TLLIPAIT----TADAGFYLCVATSPAGTAQAR---IQVVVLSASDASPPPVKIESSSPS 2061
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
+G T+ L C+ GS V W + G +L +++H G L + D+G Y
Sbjct: 2062 VTEGQTLDLNCV-VAGSAHAQVTWYRRGGSL--PPHTQVH---GSRLRLPQVSPADSGEY 2115
Query: 179 QCIARNAAGTRESAIATLKIH--------------IKPYLITGPEDVVAQTGSSVTFQCR 224
C N +G +E++I +H +P I VA+ G ++ C
Sbjct: 2116 VCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAE-GQTLDLNCV 2174
Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSA 283
V G V W + GG++P + GS LRL V AD GEY C + G + A
Sbjct: 2175 VPGQAHAQVTWHKR--GGSLP---ARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEA 2229
Query: 284 SGYLTVYDP------PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
S +T+ P + + +S V G +C G+ + W G
Sbjct: 2230 SVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG 2282
Score = 82.6 bits (195), Expect = 8e-15
Identities = 117/500 (23%), Positives = 180/500 (36%), Gaps = 69/500 (13%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA + LNC G + W+K G + S H++ G L H +D+G
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSH-HQT---RGSRLRL---HHVSPADSGE 2790
Query: 83 YWCEATNSYGTAR---------SRNATLHVAVL--REEFRLEPESKQSAQGDTVVLECLP 131
Y C S G S ++ +HV R+EP S + A+G T+ L+C+
Sbjct: 2791 YVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVV 2850
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
P G V W K G L H V G L + D+G Y C ++GT E+
Sbjct: 2851 P-GQAHAQVTWHKRGGNL-----PARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2904
Query: 192 AIATLKIHIKPYLITGP---EDVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGG 241
++ P I P + + + SS + C V G V W + G
Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR--G 2962
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--------- 292
G++P LRL V AD GEY C A + G + + P
Sbjct: 2963 GSLPARHQT--HGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLR 3020
Query: 293 -PSINLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVF 350
P I++ P S V+ G A F C P ++ W D H +
Sbjct: 3021 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQEL-------EDNVH---IS 3070
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-L 409
+++TI T + + T C A N G + L+V PP ++ P +
Sbjct: 3071 PNGSIITIVGT-RPSNHGTYRCVASNAYGVAQSVVNLSV-----HGPPTVSVLPEGPVWV 3124
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYT 466
+ C + P W + +R + + L + SD+GTY
Sbjct: 3125 KVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYV 3184
Query: 467 CVASSRHGKYVWSGALLVDS 486
C+A + G ++VD+
Sbjct: 3185 CLAQNALGTAQKQVEVIVDT 3204
Score = 70.1 bits (164), Expect = 4e-11
Identities = 73/291 (25%), Positives = 115/291 (39%), Gaps = 21/291 (7%)
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
P + G S + +C+V G P W R G +P G + L +V +D
Sbjct: 1683 PARSIVPQGGSHSLRCQVSGSPPHYFYWSRE-DGRPVPSGTQQRHQGSELHFPSVQPSDA 1741
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLS-----PNSVNVESGNVARFTCTATGR-PE 321
G Y C N + ++ L V + PS ++ S +V G F CTA + P
Sbjct: 1742 GVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPA 1801
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
T+ W+ N + P + D F+G +LTI + +D+ T VC+ N
Sbjct: 1802 YTLVWTRLHNGKL--PTRAMD-------FNG--ILTIRNVQLSDA-GTYVCTGSNMFAMD 1849
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
L V + P+++ P T+ +A F C+A +P P + W G Q
Sbjct: 1850 QGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW--TGGPGGQL 1907
Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+ + G L L ++ +D Y C A S G+ V L V P +
Sbjct: 1908 PAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TL 452
PP + P + V F C AI P PII W + + R VT++G TL
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464
Query: 453 VLKDLDKSDSGTYTCVASSRHG 474
+++D+ +SD G YTC A + G
Sbjct: 465 IIRDVKESDQGAYTCEAMNARG 486
Score = 48.4 bits (110), Expect = 2e-04
Identities = 32/85 (37%), Positives = 47/85 (55%), Gaps = 7/85 (8%)
Query: 202 PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDD---GS 256
P ++T P E + A G +VTF C G P P + WR G++P RV V + G+
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWR--LNWGHIPSHPRVTVTSEGGRGT 463
Query: 257 LRLDNVILADEGEYSCEAENSVGAV 281
L + +V +D+G Y+CEA N+ G V
Sbjct: 464 LIIRDVKESDQGAYTCEAMNARGMV 488
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQT 173
ES Q+++G TV C+ G P P + W+ N + + G G L+I+D +++
Sbjct: 414 ESIQASRGQTVTFTCVAI-GVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKES 472
Query: 174 DAGRYQCIARNAAG 187
D G Y C A NA G
Sbjct: 473 DQGAYTCEAMNARG 486
Score = 39.5 bits (88), Expect = 0.072
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 12 PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P ++ P + + +R Q T C A G P+P I W + S ++ GG L
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLI 465
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
+ SD G Y CEA N+ G
Sbjct: 466 IRDVK-ESDQGAYTCEAMNARG 486
Score = 33.5 bits (73), Expect = 4.7
Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 8/92 (8%)
Query: 292 PPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
PP + P S+ G FTC A G P P + W + P ++
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVT------VTSE 458
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
G L I D ++D + C A+N G F
Sbjct: 459 GGRGTLIIRDVKESD-QGAYTCEAMNARGMVF 489
>AL590103-2|CAI12125.1| 4391|Homo sapiens heparan sulfate proteoglycan
2 (perlecan) protein.
Length = 4391
Score = 143 bits (346), Expect = 4e-33
Identities = 151/515 (29%), Positives = 212/515 (41%), Gaps = 61/515 (11%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + + ++TV ATL C A GSP+P I W K + HR L L R
Sbjct: 3211 APQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQ-HR--LEGDTLIIPR 3267
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D+G Y C AT+ G A + LHV + PE G+TV L+CL
Sbjct: 3268 VAQ----QDSGQYICNATSPAGHAEA-TIILHVESPPYATTV-PEHASVQAGETVQLQCL 3321
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G+P W + G +L +R L L + A D+GRY+C N G+ E
Sbjct: 3322 A-HGTPPLTFQWSRVGSSLPGRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAE 3375
Query: 191 SAIATLKIHIKPYLITG--------------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
A A L + P + P+ G+SV F C V D + W
Sbjct: 3376 -AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWF 3434
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-- 294
+ GG +P G + DG LR+ N+ + +G Y C+A G AS L + PS
Sbjct: 3435 KE--GGQLPPGHS--VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL 3490
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
IN+ + V G+ F C A G P+P + WS G + PG+ + V
Sbjct: 3491 INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH--LRPGIVQSG-------GVVR 3541
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
+ + D R C+A N AG++ L V + P I + P +P S
Sbjct: 3542 IAHVELADAGQYR----CTATNAAGTTQSHVLLLVQA----LPQI--SMPQEVRVPAGSA 3591
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
AVFPC A P P I+W +L + R + L+L + D+GTY C A++R G
Sbjct: 3592 AVFPCIASGYPTPDISWSKLDGSLPPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQG 3648
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
K L V + P +F S LP P K
Sbjct: 3649 KVKAFAHLQVPERVVP---YFTQTPYSFLPLPTIK 3680
Score = 130 bits (313), Expect = 4e-29
Identities = 125/488 (25%), Positives = 192/488 (39%), Gaps = 35/488 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+P I P TV + Q A+ C +P ++ W + + H I P G + +
Sbjct: 3021 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVH--ISPNGSIITI 3078
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
T H G Y C A+N+YG A+S N ++H + PE + G V L
Sbjct: 3079 VGTRPSNH---GTYRCVASNAYGVAQSVVNLSVHGP---PTVSVLPEGPVWVKVGKAVTL 3132
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
EC+ G P + W + T L+D L I A+ +DAG Y C+A+NA
Sbjct: 3133 ECVSA-GEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNAL 3191
Query: 187 GTRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
GT + + + P + ++ + G + T +C G P P + W +
Sbjct: 3192 GTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRS- 3250
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
PL L+ +L + V D G+Y C A + G A+ L V PP P
Sbjct: 3251 ---PLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEH 3307
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+V++G + C A G P T WS G+ PG + + + F+ D+
Sbjct: 3308 ASVQAGETVQLQCLAHGTPPLTFQWSRVGSS---LPGRATAR-NELLHFERAAP---EDS 3360
Query: 362 DKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ R T + V+ G L TS P + P +T I + F
Sbjct: 3361 GRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFH 3420
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
C + W+ EG L H DG L +++LD+S GTY C A GK
Sbjct: 3421 CAVPSDRGTQLRWFKEGGQLPPGHS---VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQA 3477
Query: 479 SGALLVDS 486
S L++ +
Sbjct: 3478 SAQLVIQA 3485
Score = 118 bits (283), Expect = 2e-25
Identities = 119/479 (24%), Positives = 182/479 (37%), Gaps = 38/479 (7%)
Query: 8 SGEAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ +AP ++E P V + +L C+ GSP W + V + L
Sbjct: 1672 TNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSEL 1731
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GD 123
F SDAGVY C N + + SR L + + E ++S G
Sbjct: 1732 HFPSVQP----SDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGA 1787
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIA 182
V C SP + W T L +G +D G L I++ + +DAG Y C
Sbjct: 1788 DVTFICTAKSKSPAYTLVW-----TRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTG 1842
Query: 183 RNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
N + ATL + P + P + Q G F+C G P P + W
Sbjct: 1843 SNMF-AMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-T 1900
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--DPPSI 295
GG +P + ++ G LRL V D+ +Y C A +S G A L V+ P +
Sbjct: 1901 GGPGGQLP-AKAQI-HGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+SP V +G R C A G P T+ W EG P +R + A + +
Sbjct: 1959 QVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGS---LPPQARSERTDIAT---LLI 2012
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
I D +C A + AG++ R ++ V S D PP + S+ ++
Sbjct: 2013 PAITTAD----AGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2068
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C + + WY G +L + + + L L + +DSG Y C + G
Sbjct: 2069 DLNCVVAGSAHAQVTWYRRGGSLPPHTQ---VHGSRLRLPQVSPADSGEYVCRVENGSG 2124
Score = 108 bits (260), Expect = 1e-22
Identities = 130/482 (26%), Positives = 184/482 (38%), Gaps = 52/482 (10%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + P +TV Q A C A GSP+P + W GG I GG+ L
Sbjct: 1865 APVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-TGGPGGQLPAKAQI--HGGILRLP 1921
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLEC 129
A +D Y C A +S G +R A LHV ++ PE Q G TV L C
Sbjct: 1922 AVE---PTDQAQYLCRAHSSAGQQVAR-AVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC 1977
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G P + W+K G +L +R D L+I DAG Y C+A + AGT
Sbjct: 1978 -RAAGVPSATITWRKEGGSL--PPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTA 2034
Query: 190 ESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
++ I + + P I V + G ++ C V G V W R GG++
Sbjct: 2035 QARIQVVVLSASDASPPPVKIESSSPSVTE-GQTLDLNCVVAGSAHAQVTWYRR--GGSL 2091
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----YDPPS------ 294
P +V LRL V AD GEY C EN G AS ++V + PS
Sbjct: 2092 P-PHTQV-HGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPG 2149
Query: 295 ----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
I + P+S +V G C G+ + W G P +R + H
Sbjct: 2150 STRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGS---LP--ARHQTHG---- 2200
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTL 409
++L ++ DS VC V +G +T+ S P P + S+ T+
Sbjct: 2201 ---SLLRLHQVTPADS-GEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTV 2256
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
C + WY G +L H+ L + +D+G Y C A
Sbjct: 2257 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQ---VRGSRLYIFQASPADAGQYVCRA 2313
Query: 470 SS 471
S+
Sbjct: 2314 SN 2315
Score = 103 bits (246), Expect = 5e-21
Identities = 125/496 (25%), Positives = 194/496 (39%), Gaps = 64/496 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V G P + + TVA Q L+C G + WYK G + + R +
Sbjct: 2239 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA---RHQVRGSR 2295
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-------LHVAVLREEFRLEPESKQ 118
L+ +A+ +DAG Y C A+N + + T + A + R+EP S Q
Sbjct: 2296 LYIFQASP----ADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQ 2351
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
A+G T+ L C+ P G V W K G +L H G L + A D+G Y
Sbjct: 2352 VAEGQTLDLNCVVP-GQSHAQVTWHKRGGSL-----PVRHQTHGSLLRLYQASPADSGEY 2405
Query: 179 QC-IARNAAGTRESAIATLK-------IHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDP 229
C + ++ S + T++ + + P + I VA+ G ++ C V G
Sbjct: 2406 VCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAE-GQTLDLNCLVAGQA 2464
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
V W + GG++P R +V LRL V AD GEY C S G AS +T+
Sbjct: 2465 HAQVTWHKR--GGSLP-ARHQV-HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTI 2520
Query: 290 YDPPS----------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG----NRTII 335
S + + +S ++ +G+ C + T+ W G +R I
Sbjct: 2521 QQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI 2580
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
R T G V + ++ SR T + + +GSS V +
Sbjct: 2581 VGSRLRIP-QVTPADSGEYVCHV--SNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESS 2637
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
P ++ QTL + C P+ II WY G +L H+ T+ L L
Sbjct: 2638 SPTVV----EGQTLDLN------CVVARQPQAIITWYKRGGSLPSRHQ---THGSHLRLH 2684
Query: 456 DLDKSDSGTYTCVASS 471
+ +DSG Y C A++
Sbjct: 2685 QMSVADSGEYVCRANN 2700
Score = 96.3 bits (229), Expect = 6e-19
Identities = 126/512 (24%), Positives = 193/512 (37%), Gaps = 60/512 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + + VA Q LNC G + W+K G + + R + L
Sbjct: 2434 GVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPA---RHQVHGSRLRL 2490
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARS--------RNATLHVAVLREEFRLEPESKQSA 120
L+ T +D+G Y C S GT + R + H + R+E S A
Sbjct: 2491 LQVTP----ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLA 2546
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T+ L CL +P + W K G +L SR H + G L I D+G Y C
Sbjct: 2547 NGHTLDLNCLVASQAPH-TITWYKRGGSL----PSR-HQIVGSRLRIPQVTPADSGEYVC 2600
Query: 181 IARNAAGTRE-SAIATLK----IHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
N AG+RE S I T++ H+ P I V + G ++ C V P
Sbjct: 2601 HVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVE-GQTLDLNCVVARQPQA 2659
Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-- 289
+ W + GG++P R + LRL + +AD GEY C A N++ A+ AS ++V
Sbjct: 2660 IITWYKR--GGSLP-SRHQT-HGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSP 2715
Query: 290 -YDPPS-------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PG 338
PS I + +S +V G C G+ + W G G
Sbjct: 2716 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRG 2775
Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
+H + G V + + + +V + +GSS V + R P
Sbjct: 2776 SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLV--TIEASGSSAVHVPAPGGAPPIRIEP 2833
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ QTL +K C + W+ G L H+ + L L +
Sbjct: 2834 SSSRVAEGQTLDLK------CVVPGQAHAQVTWHKRGGNLPARHQ---VHGPLLRLNQVS 2884
Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+DSG Y+C + G + + L+ P +P
Sbjct: 2885 PADSGEYSCQVTGSSGT-LEASVLVTIEPSSP 2915
Score = 94.3 bits (224), Expect = 2e-18
Identities = 134/512 (26%), Positives = 193/512 (37%), Gaps = 79/512 (15%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILP 62
+V S P IE TV Q LNC P I WYK G + S TH S L
Sbjct: 2624 HVPSVSPPIRIESS-SPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHL- 2681
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE---------FRLE 113
H +D+G Y C A N+ A + + V+ R+E
Sbjct: 2682 --------RLHQMSVADSGEYVCRANNNID-ALEASIVISVSPSAGSPSAPGSSMPIRIE 2732
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
S A+G+T+ L C+ P G V W K G +L H G L +
Sbjct: 2733 SSSSHVAEGETLDLNCVVP-GQAHAQVTWHKRGGSL-----PSHHQTRGSRLRLHHVSPA 2786
Query: 174 DAGRYQCIARNAAGTRE-SAIATLK------IHIK-----PYLITGPEDVVAQTGSSVTF 221
D+G Y C ++G E S + T++ +H+ P + P G ++
Sbjct: 2787 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDL 2846
Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
+C V G V W + GGN+P R +V LRL+ V AD GEYSC+ S G +
Sbjct: 2847 KCVVPGQAHAQVTWHKR--GGNLP-ARHQV-HGPLLRLNQVSPADSGEYSCQVTGSSGTL 2902
Query: 282 SASGYLTVYDPPS------------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
AS +T+ +P S I + +S +V G C G+ + W
Sbjct: 2903 EASVLVTI-EPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR 2961
Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
G P +R + H + L ++ DS VC A + G TV
Sbjct: 2962 GGS---LP--ARHQTHGSQ-------LRLHLVSPADS-GEYVCRAASGPGPE-QEASFTV 3007
Query: 390 T------SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNH 442
T S P+I+ P + T+ A F C PI + W + L N
Sbjct: 3008 TVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNV 3067
Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+ N + + S+ GTY CVAS+ +G
Sbjct: 3068 HIS-PNGSIITIVGTRPSNHGTYRCVASNAYG 3098
Score = 93.9 bits (223), Expect = 3e-18
Identities = 82/286 (28%), Positives = 120/286 (41%), Gaps = 23/286 (8%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAG 64
+ +G P + P T + +C +RW+K GG L + +
Sbjct: 3394 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQD----- 3448
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G+ ++ S G Y C+A +G A++ + A+ + + G
Sbjct: 3449 GVLRIQNLD---QSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHA 3505
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
V ECL G P+P V W K G G R +V G +V I DAG+Y+C A
Sbjct: 3506 VEFECLA-LGDPKPQVTWSKVG------GHLRPGIVQSGGVVRIAHVELADAGQYRCTAT 3558
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
NAAGT +S + L + P I+ P++V GS+ F C G P PD+ W + G
Sbjct: 3559 NAAGTTQSHVLLL-VQALPQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSK-LDGSL 3615
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
P R L++ L L +V D G Y C A N G V A +L V
Sbjct: 3616 PPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3658
Score = 93.1 bits (221), Expect = 5e-18
Identities = 93/353 (26%), Positives = 137/353 (38%), Gaps = 46/353 (13%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
+V G P + P V + L CRA G PS I W K G +
Sbjct: 1949 HVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIA 2008
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQ 118
L T +DAG Y C AT+ GTA++R + V VL ++E S
Sbjct: 2009 TLLIPAIT----TADAGFYLCVATSPAGTAQAR---IQVVVLSASDASPPPVKIESSSPS 2061
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
+G T+ L C+ GS V W + G +L +++H G L + D+G Y
Sbjct: 2062 VTEGQTLDLNCV-VAGSAHAQVTWYRRGGSL--PPHTQVH---GSRLRLPQVSPADSGEY 2115
Query: 179 QCIARNAAGTRESAIATLKIH--------------IKPYLITGPEDVVAQTGSSVTFQCR 224
C N +G +E++I +H +P I VA+ G ++ C
Sbjct: 2116 VCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAE-GQTLDLNCV 2174
Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSA 283
V G V W + GG++P + GS LRL V AD GEY C + G + A
Sbjct: 2175 VPGQAHAQVTWHKR--GGSLP---ARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEA 2229
Query: 284 SGYLTVYDP------PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
S +T+ P + + +S V G +C G+ + W G
Sbjct: 2230 SVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG 2282
Score = 82.6 bits (195), Expect = 8e-15
Identities = 117/500 (23%), Positives = 180/500 (36%), Gaps = 69/500 (13%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA + LNC G + W+K G + S H++ G L H +D+G
Sbjct: 2738 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSH-HQT---RGSRLRL---HHVSPADSGE 2790
Query: 83 YWCEATNSYGTAR---------SRNATLHVAVL--REEFRLEPESKQSAQGDTVVLECLP 131
Y C S G S ++ +HV R+EP S + A+G T+ L+C+
Sbjct: 2791 YVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVV 2850
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
P G V W K G L H V G L + D+G Y C ++GT E+
Sbjct: 2851 P-GQAHAQVTWHKRGGNL-----PARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2904
Query: 192 AIATLKIHIKPYLITGP---EDVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGG 241
++ P I P + + + SS + C V G V W + G
Sbjct: 2905 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR--G 2962
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--------- 292
G++P LRL V AD GEY C A + G + + P
Sbjct: 2963 GSLPARHQT--HGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLR 3020
Query: 293 -PSINLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVF 350
P I++ P S V+ G A F C P ++ W D H +
Sbjct: 3021 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQEL-------EDNVH---IS 3070
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-L 409
+++TI T + + T C A N G + L+V PP ++ P +
Sbjct: 3071 PNGSIITIVGT-RPSNHGTYRCVASNAYGVAQSVVNLSV-----HGPPTVSVLPEGPVWV 3124
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYT 466
+ C + P W + +R + + L + SD+GTY
Sbjct: 3125 KVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYV 3184
Query: 467 CVASSRHGKYVWSGALLVDS 486
C+A + G ++VD+
Sbjct: 3185 CLAQNALGTAQKQVEVIVDT 3204
Score = 70.1 bits (164), Expect = 4e-11
Identities = 73/291 (25%), Positives = 115/291 (39%), Gaps = 21/291 (7%)
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
P + G S + +C+V G P W R G +P G + L +V +D
Sbjct: 1683 PARSIVPQGGSHSLRCQVSGSPPHYFYWSRE-DGRPVPSGTQQRHQGSELHFPSVQPSDA 1741
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLS-----PNSVNVESGNVARFTCTATGR-PE 321
G Y C N + ++ L V + PS ++ S +V G F CTA + P
Sbjct: 1742 GVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPA 1801
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
T+ W+ N + P + D F+G +LTI + +D+ T VC+ N
Sbjct: 1802 YTLVWTRLHNGKL--PTRAMD-------FNG--ILTIRNVQLSDA-GTYVCTGSNMFAMD 1849
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
L V + P+++ P T+ +A F C+A +P P + W G Q
Sbjct: 1850 QGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW--TGGPGGQL 1907
Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+ + G L L ++ +D Y C A S G+ V L V P +
Sbjct: 1908 PAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1958
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TL 452
PP + P + V F C AI P PII W + + R VT++G TL
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 464
Query: 453 VLKDLDKSDSGTYTCVASSRHG 474
+++D+ +SD G YTC A + G
Sbjct: 465 IIRDVKESDQGAYTCEAMNARG 486
Score = 48.4 bits (110), Expect = 2e-04
Identities = 32/85 (37%), Positives = 47/85 (55%), Gaps = 7/85 (8%)
Query: 202 PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDD---GS 256
P ++T P E + A G +VTF C G P P + WR G++P RV V + G+
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWR--LNWGHIPSHPRVTVTSEGGRGT 463
Query: 257 LRLDNVILADEGEYSCEAENSVGAV 281
L + +V +D+G Y+CEA N+ G V
Sbjct: 464 LIIRDVKESDQGAYTCEAMNARGMV 488
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQT 173
ES Q+++G TV C+ G P P + W+ N + + G G L+I+D +++
Sbjct: 414 ESIQASRGQTVTFTCVAI-GVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKES 472
Query: 174 DAGRYQCIARNAAG 187
D G Y C A NA G
Sbjct: 473 DQGAYTCEAMNARG 486
Score = 39.5 bits (88), Expect = 0.072
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 12 PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P ++ P + + +R Q T C A G P+P I W + S ++ GG L
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLI 465
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
+ SD G Y CEA N+ G
Sbjct: 466 IRDVK-ESDQGAYTCEAMNARG 486
Score = 33.5 bits (73), Expect = 4.7
Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 8/92 (8%)
Query: 292 PPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
PP + P S+ G FTC A G P P + W + P ++
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVT------VTSE 458
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
G L I D ++D + C A+N G F
Sbjct: 459 GGRGTLIIRDVKESD-QGAYTCEAMNARGMVF 489
>AL445795-1|CAC18534.1| 4370|Homo sapiens heparan sulfate proteoglycan
perlecan protein.
Length = 4370
Score = 143 bits (346), Expect = 4e-33
Identities = 151/515 (29%), Positives = 212/515 (41%), Gaps = 61/515 (11%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + + ++TV ATL C A GSP+P I W K + HR L L R
Sbjct: 3190 APQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQ-HR--LEGDTLIIPR 3246
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D+G Y C AT+ G A + LHV + PE G+TV L+CL
Sbjct: 3247 VAQ----QDSGQYICNATSPAGHAEA-TIILHVESPPYATTV-PEHASVQAGETVQLQCL 3300
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G+P W + G +L +R L L + A D+GRY+C N G+ E
Sbjct: 3301 A-HGTPPLTFQWSRVGSSLPGRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAE 3354
Query: 191 SAIATLKIHIKPYLITG--------------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
A A L + P + P+ G+SV F C V D + W
Sbjct: 3355 -AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWF 3413
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-- 294
+ GG +P G + DG LR+ N+ + +G Y C+A G AS L + PS
Sbjct: 3414 KE--GGQLPPGHS--VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL 3469
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
IN+ + V G+ F C A G P+P + WS G + PG+ + V
Sbjct: 3470 INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH--LRPGIVQSG-------GVVR 3520
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
+ + D R C+A N AG++ L V + P I + P +P S
Sbjct: 3521 IAHVELADAGQYR----CTATNAAGTTQSHVLLLVQA----LPQI--SMPQEVRVPAGSA 3570
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
AVFPC A P P I+W +L + R + L+L + D+GTY C A++R G
Sbjct: 3571 AVFPCIASGYPTPDISWSKLDGSLPPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQG 3627
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
K L V + P +F S LP P K
Sbjct: 3628 KVKAFAHLQVPERVVP---YFTQTPYSFLPLPTIK 3659
Score = 130 bits (313), Expect = 4e-29
Identities = 125/488 (25%), Positives = 192/488 (39%), Gaps = 35/488 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+P I P TV + Q A+ C +P ++ W + + H I P G + +
Sbjct: 3000 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVH--ISPNGSIITI 3057
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
T H G Y C A+N+YG A+S N ++H + PE + G V L
Sbjct: 3058 VGTRPSNH---GTYRCVASNAYGVAQSVVNLSVHGP---PTVSVLPEGPVWVKVGKAVTL 3111
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
EC+ G P + W + T L+D L I A+ +DAG Y C+A+NA
Sbjct: 3112 ECVSA-GEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNAL 3170
Query: 187 GTRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
GT + + + P + ++ + G + T +C G P P + W +
Sbjct: 3171 GTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRS- 3229
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
PL L+ +L + V D G+Y C A + G A+ L V PP P
Sbjct: 3230 ---PLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEH 3286
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+V++G + C A G P T WS G+ PG + + + F+ D+
Sbjct: 3287 ASVQAGETVQLQCLAHGTPPLTFQWSRVGSS---LPGRATAR-NELLHFERAAP---EDS 3339
Query: 362 DKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ R T + V+ G L TS P + P +T I + F
Sbjct: 3340 GRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFH 3399
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
C + W+ EG L H DG L +++LD+S GTY C A GK
Sbjct: 3400 CAVPSDRGTQLRWFKEGGQLPPGHS---VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQA 3456
Query: 479 SGALLVDS 486
S L++ +
Sbjct: 3457 SAQLVIQA 3464
Score = 118 bits (283), Expect = 2e-25
Identities = 119/479 (24%), Positives = 182/479 (37%), Gaps = 38/479 (7%)
Query: 8 SGEAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ +AP ++E P V + +L C+ GSP W + V + L
Sbjct: 1651 TNQAPLVVEVHPARSIVPQGGSHSLRCQVSGSPPHYFYWSREDGRPVPSGTQQRHQGSEL 1710
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GD 123
F SDAGVY C N + + SR L + + E ++S G
Sbjct: 1711 HFPSVQP----SDAGVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGA 1766
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIA 182
V C SP + W T L +G +D G L I++ + +DAG Y C
Sbjct: 1767 DVTFICTAKSKSPAYTLVW-----TRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTG 1821
Query: 183 RNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
N + ATL + P + P + Q G F+C G P P + W
Sbjct: 1822 SNMF-AMDQGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-T 1879
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--DPPSI 295
GG +P + ++ G LRL V D+ +Y C A +S G A L V+ P +
Sbjct: 1880 GGPGGQLP-AKAQI-HGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1937
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+SP V +G R C A G P T+ W EG P +R + A + +
Sbjct: 1938 QVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGS---LPPQARSERTDIAT---LLI 1991
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
I D +C A + AG++ R ++ V S D PP + S+ ++
Sbjct: 1992 PAITTAD----AGFYLCVATSPAGTAQARIQVVVLSASDASPPPVKIESSSPSVTEGQTL 2047
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C + + WY G +L + + + L L + +DSG Y C + G
Sbjct: 2048 DLNCVVAGSAHAQVTWYRRGGSLPPHTQ---VHGSRLRLPQVSPADSGEYVCRVENGSG 2103
Score = 108 bits (260), Expect = 1e-22
Identities = 130/482 (26%), Positives = 184/482 (38%), Gaps = 52/482 (10%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + P +TV Q A C A GSP+P + W GG I GG+ L
Sbjct: 1844 APVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-TGGPGGQLPAKAQI--HGGILRLP 1900
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLEC 129
A +D Y C A +S G +R A LHV ++ PE Q G TV L C
Sbjct: 1901 AVE---PTDQAQYLCRAHSSAGQQVAR-AVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC 1956
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G P + W+K G +L +R D L+I DAG Y C+A + AGT
Sbjct: 1957 -RAAGVPSATITWRKEGGSL--PPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTA 2013
Query: 190 ESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
++ I + + P I V + G ++ C V G V W R GG++
Sbjct: 2014 QARIQVVVLSASDASPPPVKIESSSPSVTE-GQTLDLNCVVAGSAHAQVTWYRR--GGSL 2070
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----YDPPS------ 294
P +V LRL V AD GEY C EN G AS ++V + PS
Sbjct: 2071 P-PHTQV-HGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPG 2128
Query: 295 ----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
I + P+S +V G C G+ + W G P +R + H
Sbjct: 2129 STRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGS---LP--ARHQTHG---- 2179
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTL 409
++L ++ DS VC V +G +T+ S P P + S+ T+
Sbjct: 2180 ---SLLRLHQVTPADS-GEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTV 2235
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
C + WY G +L H+ L + +D+G Y C A
Sbjct: 2236 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQ---VRGSRLYIFQASPADAGQYVCRA 2292
Query: 470 SS 471
S+
Sbjct: 2293 SN 2294
Score = 103 bits (246), Expect = 5e-21
Identities = 125/496 (25%), Positives = 194/496 (39%), Gaps = 64/496 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V G P + + TVA Q L+C G + WYK G + + R +
Sbjct: 2218 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA---RHQVRGSR 2274
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-------LHVAVLREEFRLEPESKQ 118
L+ +A+ +DAG Y C A+N + + T + A + R+EP S Q
Sbjct: 2275 LYIFQASP----ADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQ 2330
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
A+G T+ L C+ P G V W K G +L H G L + A D+G Y
Sbjct: 2331 VAEGQTLDLNCVVP-GQSHAQVTWHKRGGSL-----PVRHQTHGSLLRLYQASPADSGEY 2384
Query: 179 QC-IARNAAGTRESAIATLK-------IHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDP 229
C + ++ S + T++ + + P + I VA+ G ++ C V G
Sbjct: 2385 VCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAE-GQTLDLNCLVAGQA 2443
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
V W + GG++P R +V LRL V AD GEY C S G AS +T+
Sbjct: 2444 HAQVTWHKR--GGSLP-ARHQV-HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTI 2499
Query: 290 YDPPS----------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG----NRTII 335
S + + +S ++ +G+ C + T+ W G +R I
Sbjct: 2500 QQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI 2559
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
R T G V + ++ SR T + + +GSS V +
Sbjct: 2560 VGSRLRIP-QVTPADSGEYVCHV--SNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESS 2616
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
P ++ QTL + C P+ II WY G +L H+ T+ L L
Sbjct: 2617 SPTVV----EGQTLDLN------CVVARQPQAIITWYKRGGSLPSRHQ---THGSHLRLH 2663
Query: 456 DLDKSDSGTYTCVASS 471
+ +DSG Y C A++
Sbjct: 2664 QMSVADSGEYVCRANN 2679
Score = 96.3 bits (229), Expect = 6e-19
Identities = 126/512 (24%), Positives = 193/512 (37%), Gaps = 60/512 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + + VA Q LNC G + W+K G + + R + L
Sbjct: 2413 GVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPA---RHQVHGSRLRL 2469
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARS--------RNATLHVAVLREEFRLEPESKQSA 120
L+ T +D+G Y C S GT + R + H + R+E S A
Sbjct: 2470 LQVTP----ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLA 2525
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T+ L CL +P + W K G +L SR H + G L I D+G Y C
Sbjct: 2526 NGHTLDLNCLVASQAPH-TITWYKRGGSL----PSR-HQIVGSRLRIPQVTPADSGEYVC 2579
Query: 181 IARNAAGTRE-SAIATLK----IHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
N AG+RE S I T++ H+ P I V + G ++ C V P
Sbjct: 2580 HVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVE-GQTLDLNCVVARQPQA 2638
Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-- 289
+ W + GG++P R + LRL + +AD GEY C A N++ A+ AS ++V
Sbjct: 2639 IITWYKR--GGSLP-SRHQT-HGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSP 2694
Query: 290 -YDPPS-------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PG 338
PS I + +S +V G C G+ + W G G
Sbjct: 2695 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRG 2754
Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
+H + G V + + + +V + +GSS V + R P
Sbjct: 2755 SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLV--TIEASGSSAVHVPAPGGAPPIRIEP 2812
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ QTL +K C + W+ G L H+ + L L +
Sbjct: 2813 SSSRVAEGQTLDLK------CVVPGQAHAQVTWHKRGGNLPARHQ---VHGPLLRLNQVS 2863
Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+DSG Y+C + G + + L+ P +P
Sbjct: 2864 PADSGEYSCQVTGSSGT-LEASVLVTIEPSSP 2894
Score = 94.3 bits (224), Expect = 2e-18
Identities = 134/512 (26%), Positives = 193/512 (37%), Gaps = 79/512 (15%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILP 62
+V S P IE TV Q LNC P I WYK G + S TH S L
Sbjct: 2603 HVPSVSPPIRIESS-SPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHL- 2660
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE---------FRLE 113
H +D+G Y C A N+ A + + V+ R+E
Sbjct: 2661 --------RLHQMSVADSGEYVCRANNNID-ALEASIVISVSPSAGSPSAPGSSMPIRIE 2711
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
S A+G+T+ L C+ P G V W K G +L H G L +
Sbjct: 2712 SSSSHVAEGETLDLNCVVP-GQAHAQVTWHKRGGSL-----PSHHQTRGSRLRLHHVSPA 2765
Query: 174 DAGRYQCIARNAAGTRE-SAIATLK------IHIK-----PYLITGPEDVVAQTGSSVTF 221
D+G Y C ++G E S + T++ +H+ P + P G ++
Sbjct: 2766 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDL 2825
Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
+C V G V W + GGN+P R +V LRL+ V AD GEYSC+ S G +
Sbjct: 2826 KCVVPGQAHAQVTWHKR--GGNLP-ARHQV-HGPLLRLNQVSPADSGEYSCQVTGSSGTL 2881
Query: 282 SASGYLTVYDPPS------------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
AS +T+ +P S I + +S +V G C G+ + W
Sbjct: 2882 EASVLVTI-EPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR 2940
Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
G P +R + H + L ++ DS VC A + G TV
Sbjct: 2941 GGS---LP--ARHQTHGSQ-------LRLHLVSPADS-GEYVCRAASGPGPE-QEASFTV 2986
Query: 390 T------SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNH 442
T S P+I+ P + T+ A F C PI + W + L N
Sbjct: 2987 TVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNV 3046
Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+ N + + S+ GTY CVAS+ +G
Sbjct: 3047 HIS-PNGSIITIVGTRPSNHGTYRCVASNAYG 3077
Score = 93.9 bits (223), Expect = 3e-18
Identities = 82/286 (28%), Positives = 120/286 (41%), Gaps = 23/286 (8%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAG 64
+ +G P + P T + +C +RW+K GG L + +
Sbjct: 3373 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQD----- 3427
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G+ ++ S G Y C+A +G A++ + A+ + + G
Sbjct: 3428 GVLRIQNLD---QSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHA 3484
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
V ECL G P+P V W K G G R +V G +V I DAG+Y+C A
Sbjct: 3485 VEFECLA-LGDPKPQVTWSKVG------GHLRPGIVQSGGVVRIAHVELADAGQYRCTAT 3537
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
NAAGT +S + L + P I+ P++V GS+ F C G P PD+ W + G
Sbjct: 3538 NAAGTTQSHVLLL-VQALPQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSK-LDGSL 3594
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
P R L++ L L +V D G Y C A N G V A +L V
Sbjct: 3595 PPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 3637
Score = 93.1 bits (221), Expect = 5e-18
Identities = 93/353 (26%), Positives = 137/353 (38%), Gaps = 46/353 (13%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
+V G P + P V + L CRA G PS I W K G +
Sbjct: 1928 HVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIA 1987
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE------FRLEPESKQ 118
L T +DAG Y C AT+ GTA++R + V VL ++E S
Sbjct: 1988 TLLIPAIT----TADAGFYLCVATSPAGTAQAR---IQVVVLSASDASPPPVKIESSSPS 2040
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
+G T+ L C+ GS V W + G +L +++H G L + D+G Y
Sbjct: 2041 VTEGQTLDLNCV-VAGSAHAQVTWYRRGGSL--PPHTQVH---GSRLRLPQVSPADSGEY 2094
Query: 179 QCIARNAAGTRESAIATLKIH--------------IKPYLITGPEDVVAQTGSSVTFQCR 224
C N +G +E++I +H +P I VA+ G ++ C
Sbjct: 2095 VCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAE-GQTLDLNCV 2153
Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSA 283
V G V W + GG++P + GS LRL V AD GEY C + G + A
Sbjct: 2154 VPGQAHAQVTWHKR--GGSLP---ARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEA 2208
Query: 284 SGYLTVYDP------PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
S +T+ P + + +S V G +C G+ + W G
Sbjct: 2209 SVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG 2261
Score = 82.6 bits (195), Expect = 8e-15
Identities = 117/500 (23%), Positives = 180/500 (36%), Gaps = 69/500 (13%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA + LNC G + W+K G + S H++ G L H +D+G
Sbjct: 2717 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSH-HQT---RGSRLRL---HHVSPADSGE 2769
Query: 83 YWCEATNSYGTAR---------SRNATLHVAVL--REEFRLEPESKQSAQGDTVVLECLP 131
Y C S G S ++ +HV R+EP S + A+G T+ L+C+
Sbjct: 2770 YVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVV 2829
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
P G V W K G L H V G L + D+G Y C ++GT E+
Sbjct: 2830 P-GQAHAQVTWHKRGGNL-----PARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2883
Query: 192 AIATLKIHIKPYLITGP---EDVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGG 241
++ P I P + + + SS + C V G V W + G
Sbjct: 2884 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR--G 2941
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--------- 292
G++P LRL V AD GEY C A + G + + P
Sbjct: 2942 GSLPARHQT--HGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLR 2999
Query: 293 -PSINLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVF 350
P I++ P S V+ G A F C P ++ W D H +
Sbjct: 3000 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQEL-------EDNVH---IS 3049
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-L 409
+++TI T + + T C A N G + L+V PP ++ P +
Sbjct: 3050 PNGSIITIVGT-RPSNHGTYRCVASNAYGVAQSVVNLSV-----HGPPTVSVLPEGPVWV 3103
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYT 466
+ C + P W + +R + + L + SD+GTY
Sbjct: 3104 KVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYV 3163
Query: 467 CVASSRHGKYVWSGALLVDS 486
C+A + G ++VD+
Sbjct: 3164 CLAQNALGTAQKQVEVIVDT 3183
Score = 70.1 bits (164), Expect = 4e-11
Identities = 73/291 (25%), Positives = 115/291 (39%), Gaps = 21/291 (7%)
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
P + G S + +C+V G P W R G +P G + L +V +D
Sbjct: 1662 PARSIVPQGGSHSLRCQVSGSPPHYFYWSRE-DGRPVPSGTQQRHQGSELHFPSVQPSDA 1720
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLS-----PNSVNVESGNVARFTCTATGR-PE 321
G Y C N + ++ L V + PS ++ S +V G F CTA + P
Sbjct: 1721 GVYICTCRNLHQSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPA 1780
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
T+ W+ N + P + D F+G +LTI + +D+ T VC+ N
Sbjct: 1781 YTLVWTRLHNGKL--PTRAMD-------FNG--ILTIRNVQLSDA-GTYVCTGSNMFAMD 1828
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
L V + P+++ P T+ +A F C+A +P P + W G Q
Sbjct: 1829 QGTATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW--TGGPGGQL 1886
Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+ + G L L ++ +D Y C A S G+ V L V P +
Sbjct: 1887 PAKAQIHGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRV 1937
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/82 (34%), Positives = 40/82 (48%), Gaps = 4/82 (4%)
Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TL 452
PP + P + V F C AI P PII W + + R VT++G TL
Sbjct: 384 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTL 443
Query: 453 VLKDLDKSDSGTYTCVASSRHG 474
+++D+ +SD G YTC A + G
Sbjct: 444 IIRDVKESDQGAYTCEAMNARG 465
Score = 48.4 bits (110), Expect = 2e-04
Identities = 32/85 (37%), Positives = 47/85 (55%), Gaps = 7/85 (8%)
Query: 202 PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDD---GS 256
P ++T P E + A G +VTF C G P P + WR G++P RV V + G+
Sbjct: 385 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWR--LNWGHIPSHPRVTVTSEGGRGT 442
Query: 257 LRLDNVILADEGEYSCEAENSVGAV 281
L + +V +D+G Y+CEA N+ G V
Sbjct: 443 LIIRDVKESDQGAYTCEAMNARGMV 467
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQT 173
ES Q+++G TV C+ G P P + W+ N + + G G L+I+D +++
Sbjct: 393 ESIQASRGQTVTFTCVAI-GVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLIIRDVKES 451
Query: 174 DAGRYQCIARNAAG 187
D G Y C A NA G
Sbjct: 452 DQGAYTCEAMNARG 465
Score = 39.5 bits (88), Expect = 0.072
Identities = 25/82 (30%), Positives = 36/82 (43%), Gaps = 2/82 (2%)
Query: 12 PYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P ++ P + + +R Q T C A G P+P I W + S ++ GG L
Sbjct: 385 PQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGGRGTLI 444
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
+ SD G Y CEA N+ G
Sbjct: 445 IRDVK-ESDQGAYTCEAMNARG 465
Score = 33.5 bits (73), Expect = 4.7
Identities = 24/92 (26%), Positives = 34/92 (36%), Gaps = 8/92 (8%)
Query: 292 PPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
PP + P S+ G FTC A G P P + W + P ++
Sbjct: 384 PPQVVTPPRESIQASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVT------VTSE 437
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
G L I D ++D + C A+N G F
Sbjct: 438 GGRGTLIIRDVKESD-QGAYTCEAMNARGMVF 468
>AB209350-1|BAD92587.1| 773|Homo sapiens PTK7 protein tyrosine
kinase 7 isoform a precursor variant protein.
Length = 773
Score = 142 bits (345), Expect = 5e-33
Identities = 122/468 (26%), Positives = 199/468 (42%), Gaps = 36/468 (7%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
++ P DV VAR++ A +C+ P P+++W +++ R+ + A G
Sbjct: 267 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 326
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
L R +AG+Y C G ATLH+A + + EP + + V
Sbjct: 327 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 382
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG
Sbjct: 383 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 438
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
R + + + P + P+D + G C P P V+W R+ +
Sbjct: 439 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 496
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN-VES 306
R +V +G+LR+++V + D Y C + G++ A + V + P +E
Sbjct: 497 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLEKLKFTPPPQPQQCMEF 556
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
A C+ATGR +PT+ W G S ++ V D L ++D+
Sbjct: 557 DKEATVPCSATGREKPTIKWERAD-------GSSLPEW----VTDNAGTLHFARVTRDDA 605
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
N ++ G +LTV P T+ A+ C A P+
Sbjct: 606 GNYTCIASNGPQGQIRAHVQLTVAVFIT-----FKVEPERTTVYQGHTALLQCEAQGDPK 660
Query: 427 PIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P+I W + L R ++ +G+LV+ D+ DSG YTC+A +
Sbjct: 661 PLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGN 708
Score = 108 bits (260), Expect = 1e-22
Identities = 127/474 (26%), Positives = 191/474 (40%), Gaps = 41/474 (8%)
Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69
P +++ P + + TL C G P P +W++ G L ++ ++ L
Sbjct: 168 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 227
Query: 70 RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125
R G HS G+Y C A +++G A S+N TL +A E F L P+ A+ +
Sbjct: 228 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 282
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180
+ C P P++ W +T + + HL G+L++ R +AG Y+C
Sbjct: 283 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 341
Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
I + G ATL + I+ + P A + VT G P P V W +
Sbjct: 342 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 399
Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
G +P GRV L L N+ +D G Y+C A N G +TV PS
Sbjct: 400 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 457
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P +E G C P+PT+ W N+ +I S D VF T L I
Sbjct: 458 PQDSQLEEGKPGYLDCLTQATPKPTVVW--YRNQMLI----SEDS--RFEVFKNGT-LRI 508
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N + D C + AGS + ++ V PP Q + A P
Sbjct: 509 NSVEVYDG-TWYRCMSSTPAGSIEAQARVQVLEKLKFTPP----PQPQQCMEFDKEATVP 563
Query: 419 CTAICTPEPIIAW-YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
C+A +P I W +G +L + N GTL + + D+G YTC+AS+
Sbjct: 564 CSATGREKPTIKWERADGSSLPE---WVTDNAGTLHFARVTRDDAGNYTCIASN 614
Score = 101 bits (243), Expect = 1e-20
Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+QP + + A L C +P P + W G V DT R L F A
Sbjct: 75 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 130
Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128
R+ D+G + C A + ARS NA+ ++ + P S+ Q T V L
Sbjct: 131 DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 189
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
C G P P W ++G T L DG S H V NL ++ A +G Y C A +A
Sbjct: 190 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 246
Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
G S TL I + + ++ P+DVV F C+ P P + W
Sbjct: 247 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 306
Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296
+ P L R V +GSL L V + G Y C + G + L + + +
Sbjct: 307 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 366
Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
L V +G+ R TC G PEP+++W G R P R V+
Sbjct: 367 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 415
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L + + ++D+ C A N AG +TV + P P + L
Sbjct: 416 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 469
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G
Sbjct: 470 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 528
Score = 88.6 bits (210), Expect = 1e-16
Identities = 74/280 (26%), Positives = 115/280 (41%), Gaps = 18/280 (6%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +T P +++P D + +P L+C +P P + WY+ +L+ D+ +
Sbjct: 443 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 502
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ 121
G L R V+ D Y C ++ G S A V VL + +F P+ +Q +
Sbjct: 503 NGTL---RINSVEVY-DGTWYRCMSSTPAG---SIEAQARVQVLEKLKFTPPPQPQQCME 555
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAGRYQ 179
D G +P + W++ DG S V + G L + DAG Y
Sbjct: 556 FDKEATVPCSATGREKPTIKWERA------DGSSLPEWVTDNAGTLHFARVTRDDAGNYT 609
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RS 238
CIA N + A L + + PE G + QC GDP P + W+ +
Sbjct: 610 CIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKD 669
Query: 239 AGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAENS 277
LG R+ + +GSL + +V D G Y+C A NS
Sbjct: 670 RILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNS 709
Score = 83.0 bits (196), Expect = 6e-15
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +P S+ + QG +L C P +VYW +G + D+ G +L
Sbjct: 74 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 129
Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222
R D+G +QC+AR+ E+ A +IK P ++ P + Q + VT +
Sbjct: 130 VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 189
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280
C + G P P W R + V + +L L G YSC A ++ G A
Sbjct: 190 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 249
Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
S+ + L++ D + L+P V V A F C + +P P++ W E I
Sbjct: 250 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 309
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396
AT +G +LT + + C G + L + +D P
Sbjct: 310 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 366
Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451
P + T G + LP K + PEP + W G L H R
Sbjct: 367 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 415
Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
LVL ++ +SD+G YTC A++ G+
Sbjct: 416 LVLANIAESDAGVYTCHAANLAGQ 439
Score = 81.8 bits (193), Expect = 1e-14
Identities = 57/166 (34%), Positives = 79/166 (47%), Gaps = 13/166 (7%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
AT+ C A G P I+W + + + AG L F R T DAG Y C A+
Sbjct: 560 ATVPCSATGREKPTIKWERADGSSLPEWVTD--NAGTLHFARVTR----DDAGNYTCIAS 613
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
N + L VAV F++EPE QG T +L+C +G P+P + WK G+
Sbjct: 614 NGPQGQIRAHVQLTVAVFIT-FKVEPERTTVYQGHTALLQC-EAQGDPKPLIQWK--GKD 669
Query: 149 LLFDGDS---RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
+ D RMH+ G+LVI D D+GRY CIA N+ + +
Sbjct: 670 RILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHT 715
>AB209851-1|BAD93088.1| 2331|Homo sapiens Basement membrane-specific
heparan sulfate proteoglycan core protein precursor
protein.
Length = 2331
Score = 142 bits (344), Expect = 7e-33
Identities = 150/515 (29%), Positives = 211/515 (40%), Gaps = 61/515 (11%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + + ++TV ATL C A GSP+P I W K L + L L R
Sbjct: 1151 APQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSK---LRSPLPWQYRLEGDTLIIPR 1207
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D+G Y C AT+ G A + LHV + PE G+TV L+CL
Sbjct: 1208 VAQ----QDSGQYICNATSPAGHAEA-TIILHVESPPYATTV-PEHASVQAGETVQLQCL 1261
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G+P W + G +L +R L L + A D+GRY+C N G+ E
Sbjct: 1262 A-HGTPPLTFQWSRVGSSLPGRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAE 1315
Query: 191 SAIATLKIHIKPYLITG--------------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
A A L + P + P+ G+SV F C V D + W
Sbjct: 1316 -AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWF 1374
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-- 294
+ GG +P G + DG LR+ N+ + +G Y C+A G AS L + PS
Sbjct: 1375 KE--GGQLPPGHS--VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL 1430
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
IN+ + V G+ F C A G P+P + WS G + PG+ + V
Sbjct: 1431 INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH--LRPGIVQSG-------GVVR 1481
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
+ + D R C+A N AG++ L V + P I + P +P S
Sbjct: 1482 IAHVELADAGQYR----CTATNAAGTTQSHVLLLVQA----LPQI--SMPQEVRVPAGSA 1531
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
AVFPC A P P I+W +L + R + L+L + D+GTY C A++R G
Sbjct: 1532 AVFPCIASGYPTPDISWSKLDGSLPPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQG 1588
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
K L V + P +F S LP P K
Sbjct: 1589 KVKAFAHLQVPERVVP---YFTQTPYSFLPLPTIK 1620
Score = 129 bits (312), Expect = 5e-29
Identities = 125/488 (25%), Positives = 192/488 (39%), Gaps = 35/488 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+P I P TV + Q A+ C +P ++ W + + H I P G + +
Sbjct: 961 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVH--ISPNGSIITI 1018
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
T H G Y C A+N+YG A+S N ++H + PE + G V L
Sbjct: 1019 VGTRPSNH---GTYRCVASNAYGVAQSVVNLSVHGP---PTVSVLPEGPVWVKVGKAVTL 1072
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
EC+ G P + W + T L+D L I A+ +DAG Y C+A+NA
Sbjct: 1073 ECVSA-GEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYVCLAQNAL 1131
Query: 187 GTRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
GT + + + P + ++ + G + T +C G P P + W +
Sbjct: 1132 GTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPAPTIHWSKLRS- 1190
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
PL L+ +L + V D G+Y C A + G A+ L V PP P
Sbjct: 1191 ---PLPWQYRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEH 1247
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+V++G + C A G P T WS G+ PG + + + F+ D+
Sbjct: 1248 ASVQAGETVQLQCLAHGTPPLTFQWSRVGSS---LPGRATAR-NELLHFERAAP---EDS 1300
Query: 362 DKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ R T + V+ G L TS P + P +T I + F
Sbjct: 1301 GRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFH 1360
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
C + W+ EG L H DG L +++LD+S GTY C A GK
Sbjct: 1361 CAVPSDRGTQLRWFKEGGQLPPGHS---VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQA 1417
Query: 479 SGALLVDS 486
S L++ +
Sbjct: 1418 SAQLVIQA 1425
Score = 108 bits (259), Expect = 1e-22
Identities = 124/502 (24%), Positives = 194/502 (38%), Gaps = 50/502 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G AP I +P VA Q L C G + W+K G + + H+ G L
Sbjct: 764 GGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKRGGNLPA-RHQV---HGPLLR 819
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR---------SRNATLHVAVLREEFRLEPESKQS 119
L +D+G Y C+ T S GT S + L + +E S
Sbjct: 820 LNQVSP---ADSGEYSCQVTGSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHV 876
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
+G T+ L C+ P G V W K G +L H G L + D+G Y
Sbjct: 877 TEGQTLDLNCVVP-GQAHAQVTWYKRGGSL-----PARHQTHGSQLRLHLVSPADSGEYV 930
Query: 180 CIARNAAGTRESAIATLKIHIK---------PYLITGPEDVVAQTGSSVTFQCRVGGDPL 230
C A + G + A T+ + P + P Q G +F+C +
Sbjct: 931 CRAASGPGPEQEASFTVTVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAA 990
Query: 231 PDVL-WRRSAGGGNMPL-GRVKVLDDGSL-RLDNVILADEGEYSCEAENSVGAVSASGYL 287
P L W+ N L V + +GS+ + ++ G Y C A N+ G + L
Sbjct: 991 PISLEWKTR----NQELEDNVHISPNGSIITIVGTRPSNHGTYRCVASNAYGVAQSVVNL 1046
Query: 288 TVYDPPSINLSPNS-VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
+V+ PP++++ P V V+ G C + G P + W+ R P + +
Sbjct: 1047 SVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWT----RISSTPAKLEQRTYG 1102
Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP-PPIITNGPS 405
+ D VL I+ +D+ T VC A N G++ + ++ V + P P + +
Sbjct: 1103 --LMDSHAVLQISSAKPSDA-GTYVCLAQNALGTAQKQVEVIVDTGAMAPGAPQVQAEEA 1159
Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
T+ A C+A +P P I W L +R TL++ + + DSG Y
Sbjct: 1160 ELTVEAGHTATLRCSATGSPAPTIHWSKLRSPLPWQYR---LEGDTLIIPRVAQQDSGQY 1216
Query: 466 TCVASSRHGKYVWSGALLVDSP 487
C A+S G + L V+SP
Sbjct: 1217 ICNATSPAGHAEATIILHVESP 1238
Score = 103 bits (246), Expect = 5e-21
Identities = 125/496 (25%), Positives = 194/496 (39%), Gaps = 64/496 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V G P + + TVA Q L+C G + WYK G + + R +
Sbjct: 179 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA---RHQVRGSR 235
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-------LHVAVLREEFRLEPESKQ 118
L+ +A+ +DAG Y C A+N + + T + A + R+EP S Q
Sbjct: 236 LYIFQASP----ADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQ 291
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
A+G T+ L C+ P G V W K G +L H G L + A D+G Y
Sbjct: 292 VAEGQTLDLNCVVP-GQSHAQVTWHKRGGSL-----PVRHQTHGSLLRLYQASPADSGEY 345
Query: 179 QC-IARNAAGTRESAIATLK-------IHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDP 229
C + ++ S + T++ + + P + I VA+ G ++ C V G
Sbjct: 346 VCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAE-GQTLDLNCLVAGQA 404
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
V W + GG++P R +V LRL V AD GEY C S G AS +T+
Sbjct: 405 HAQVTWHKR--GGSLP-ARHQV-HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTI 460
Query: 290 YDPPS----------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG----NRTII 335
S + + +S ++ +G+ C + T+ W G +R I
Sbjct: 461 QQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQI 520
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
R T G V + ++ SR T + + +GSS V +
Sbjct: 521 VGSRLRIP-QVTPADSGEYVCHV--SNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESS 577
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
P ++ QTL + C P+ II WY G +L H+ T+ L L
Sbjct: 578 SPTVV----EGQTLDLN------CVVARQPQAIITWYKRGGSLPSRHQ---THGSHLRLH 624
Query: 456 DLDKSDSGTYTCVASS 471
+ +DSG Y C A++
Sbjct: 625 QMSVADSGEYVCRANN 640
Score = 96.3 bits (229), Expect = 6e-19
Identities = 126/512 (24%), Positives = 193/512 (37%), Gaps = 60/512 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + + VA Q LNC G + W+K G + + R + L
Sbjct: 374 GVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPA---RHQVHGSRLRL 430
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARS--------RNATLHVAVLREEFRLEPESKQSA 120
L+ T +D+G Y C S GT + R + H + R+E S A
Sbjct: 431 LQVTP----ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLA 486
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T+ L CL +P + W K G +L SR H + G L I D+G Y C
Sbjct: 487 NGHTLDLNCLVASQAPH-TITWYKRGGSL----PSR-HQIVGSRLRIPQVTPADSGEYVC 540
Query: 181 IARNAAGTRE-SAIATLK----IHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
N AG+RE S I T++ H+ P I V + G ++ C V P
Sbjct: 541 HVSNGAGSRETSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVE-GQTLDLNCVVARQPQA 599
Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-- 289
+ W + GG++P R + LRL + +AD GEY C A N++ A+ AS ++V
Sbjct: 600 IITWYKR--GGSLP-SRHQT-HGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSP 655
Query: 290 -YDPPS-------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PG 338
PS I + +S +V G C G+ + W G G
Sbjct: 656 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSHHQTRG 715
Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
+H + G V + + + +V + +GSS V + R P
Sbjct: 716 SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLV--TIEASGSSAVHVPAPGGAPPIRIEP 773
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ QTL +K C + W+ G L H+ + L L +
Sbjct: 774 SSSRVAEGQTLDLK------CVVPGQAHAQVTWHKRGGNLPARHQ---VHGPLLRLNQVS 824
Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+DSG Y+C + G + + L+ P +P
Sbjct: 825 PADSGEYSCQVTGSSGT-LEASVLVTIEPSSP 855
Score = 94.3 bits (224), Expect = 2e-18
Identities = 134/512 (26%), Positives = 193/512 (37%), Gaps = 79/512 (15%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILP 62
+V S P IE TV Q LNC P I WYK G + S TH S L
Sbjct: 564 HVPSVSPPIRIESS-SPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHL- 621
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE---------FRLE 113
H +D+G Y C A N+ A + + V+ R+E
Sbjct: 622 --------RLHQMSVADSGEYVCRANNNID-ALEASIVISVSPSAGSPSAPGSSMPIRIE 672
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT 173
S A+G+T+ L C+ P G V W K G +L H G L +
Sbjct: 673 SSSSHVAEGETLDLNCVVP-GQAHAQVTWHKRGGSL-----PSHHQTRGSRLRLHHVSPA 726
Query: 174 DAGRYQCIARNAAGTRE-SAIATLK------IHIK-----PYLITGPEDVVAQTGSSVTF 221
D+G Y C ++G E S + T++ +H+ P + P G ++
Sbjct: 727 DSGEYVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDL 786
Query: 222 QCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
+C V G V W + GGN+P R +V LRL+ V AD GEYSC+ S G +
Sbjct: 787 KCVVPGQAHAQVTWHKR--GGNLP-ARHQV-HGPLLRLNQVSPADSGEYSCQVTGSSGTL 842
Query: 282 SASGYLTVYDPPS------------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
AS +T+ +P S I + +S +V G C G+ + W
Sbjct: 843 EASVLVTI-EPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR 901
Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
G P +R + H + L ++ DS VC A + G TV
Sbjct: 902 GGS---LP--ARHQTHGSQ-------LRLHLVSPADS-GEYVCRAASGPGPE-QEASFTV 947
Query: 390 T------SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNH 442
T S P+I+ P + T+ A F C PI + W + L N
Sbjct: 948 TVPPSEGSSYRLRSPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNV 1007
Query: 443 RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+ N + + S+ GTY CVAS+ +G
Sbjct: 1008 HIS-PNGSIITIVGTRPSNHGTYRCVASNAYG 1038
Score = 93.9 bits (223), Expect = 3e-18
Identities = 82/286 (28%), Positives = 120/286 (41%), Gaps = 23/286 (8%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAG 64
+ +G P + P T + +C +RW+K GG L + +
Sbjct: 1334 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQD----- 1388
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G+ ++ S G Y C+A +G A++ + A+ + + G
Sbjct: 1389 GVLRIQNLD---QSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHA 1445
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
V ECL G P+P V W K G G R +V G +V I DAG+Y+C A
Sbjct: 1446 VEFECLA-LGDPKPQVTWSKVG------GHLRPGIVQSGGVVRIAHVELADAGQYRCTAT 1498
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
NAAGT +S + L + P I+ P++V GS+ F C G P PD+ W + G
Sbjct: 1499 NAAGTTQSHVLLL-VQALPQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSK-LDGSL 1555
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
P R L++ L L +V D G Y C A N G V A +L V
Sbjct: 1556 PPDSR---LENNMLMLPSVRPQDAGTYVCTATNRQGKVKAFAHLQV 1598
Score = 86.6 bits (205), Expect = 5e-16
Identities = 121/485 (24%), Positives = 179/485 (36%), Gaps = 61/485 (12%)
Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVV-SDTHRSILPAGGLFFLRATHG 74
+P VA Q LNC G + W+K GG L TH S+L H
Sbjct: 97 EPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGSLPARHQTHGSLL---------RLHQ 147
Query: 75 RVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLR---EEFRLEPESKQSAQGDTVVLECL 130
+D+G Y C + G S T+ +V+ R+E S A+G T+ L C+
Sbjct: 148 VTPADSGEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCV 207
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN------ 184
G V W K G +L H V G L I A DAG+Y C A N
Sbjct: 208 -VAGQAHAQVTWYKRGGSL-----PARHQVRGSRLYIFQASPADAGQYVCRASNGMEASI 261
Query: 185 ---AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
GT+ + +A +P I VA+ G ++ C V G V W + G
Sbjct: 262 TVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAE-GQTLDLNCVVPGQSHAQVTWHKR--G 318
Query: 242 GNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--------- 291
G++P V+ GS LRL AD GEY C S + AS +T+
Sbjct: 319 GSLP---VRHQTHGSLLRLYQASPADSGEYVCRVLGSSVPLEASVLVTIEPAGSVPALGV 375
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P++ + +S V G C G+ + W G P +R + H +
Sbjct: 376 TPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGS---LP--ARHQVHGSR--- 427
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV--RGKLTVTSDDDRPPPIITNGPSNQTL 409
+ +L + D + +V S+ S V + +L+ + P+ S+ +L
Sbjct: 428 -LRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIES-SSASL 485
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
C I WY G +L H+ L + + +DSG Y C
Sbjct: 486 ANGHTLDLNCLVASQAPHTITWYKRGGSLPSRHQ---IVGSRLRIPQVTPADSGEYVCHV 542
Query: 470 SSRHG 474
S+ G
Sbjct: 543 SNGAG 547
Score = 82.6 bits (195), Expect = 8e-15
Identities = 117/500 (23%), Positives = 180/500 (36%), Gaps = 69/500 (13%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA + LNC G + W+K G + S H++ G L H +D+G
Sbjct: 678 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSH-HQT---RGSRLRL---HHVSPADSGE 730
Query: 83 YWCEATNSYGTAR---------SRNATLHVAVL--REEFRLEPESKQSAQGDTVVLECLP 131
Y C S G S ++ +HV R+EP S + A+G T+ L+C+
Sbjct: 731 YVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVV 790
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
P G V W K G L H V G L + D+G Y C ++GT E+
Sbjct: 791 P-GQAHAQVTWHKRGGNL-----PARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 844
Query: 192 AIATLKIHIKPYLITGP---EDVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGG 241
++ P I P + + + SS + C V G V W + G
Sbjct: 845 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR--G 902
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--------- 292
G++P LRL V AD GEY C A + G + + P
Sbjct: 903 GSLPARHQT--HGSQLRLHLVSPADSGEYVCRAASGPGPEQEASFTVTVPPSEGSSYRLR 960
Query: 293 -PSINLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVF 350
P I++ P S V+ G A F C P ++ W D H +
Sbjct: 961 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQEL-------EDNVH---IS 1010
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-L 409
+++TI T + + T C A N G + L+V PP ++ P +
Sbjct: 1011 PNGSIITIVGT-RPSNHGTYRCVASNAYGVAQSVVNLSV-----HGPPTVSVLPEGPVWV 1064
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYT 466
+ C + P W + +R + + L + SD+GTY
Sbjct: 1065 KVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHAVLQISSAKPSDAGTYV 1124
Query: 467 CVASSRHGKYVWSGALLVDS 486
C+A + G ++VD+
Sbjct: 1125 CLAQNALGTAQKQVEVIVDT 1144
Score = 77.8 bits (183), Expect = 2e-13
Identities = 117/473 (24%), Positives = 171/473 (36%), Gaps = 57/473 (12%)
Query: 22 TVARHQPATLNCRAGGSPSPAIRWYK-GGVLVV-SDTHRSIL------PA-GGLFFLRAT 72
+V Q LNC GS + WY+ GG L + H S L PA G + R
Sbjct: 1 SVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVHGSRLRLPQVSPADSGEYVCRVE 60
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
+G +A + + +GT + T V R+EP S A+G T+ L C+ P
Sbjct: 61 NGSGPKEASI---TVSVLHGTHSGPSYT-PVPGSTRPIRIEPSSSHVAEGQTLDLNCVVP 116
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE-S 191
G V W K G +L H G L + D+G Y C +G E S
Sbjct: 117 -GQAHAQVTWHKRGGSL-----PARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEAS 170
Query: 192 AIATLKIH-----IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+ T++ I P I VA+ G ++ C V G V W + GG++P
Sbjct: 171 VLVTIEASVIPGPIPPVRIESSSSTVAE-GQTLDLSCVVAGQAHAQVTWYKR--GGSLP- 226
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAEN------SVGAVSASGYLTVYDPPS---INL 297
R +V L + AD G+Y C A N +V G Y S I +
Sbjct: 227 ARHQV-RGSRLYIFQASPADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRI 285
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII---FPGMSRDKYHATAVFDGVT 354
P+S V G C G+ + W G + G Y A+ G
Sbjct: 286 EPSSSQVAEGQTLDLNCVVPGQSHAQVTWHKRGGSLPVRHQTHGSLLRLYQASPADSGEY 345
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
V + + + +V + AGS G +T T + + G QTL +
Sbjct: 346 VCRVLGSSVPLEASVLV--TIEPAGSVPALG-VTPTVRIESSSSQVAEG---QTLDLN-- 397
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
C + W+ G +L H+ + L L + +DSG Y C
Sbjct: 398 ----CLVAGQAHAQVTWHKRGGSLPARHQ---VHGSRLRLLQVTPADSGEYVC 443
Score = 53.2 bits (122), Expect = 5e-06
Identities = 67/271 (24%), Positives = 99/271 (36%), Gaps = 35/271 (12%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275
G ++ C V G V W R GG++P +V LRL V AD GEY C E
Sbjct: 5 GQTLDLNCVVAGSAHAQVTWYRR--GGSLP-PHTQV-HGSRLRLPQVSPADSGEYVCRVE 60
Query: 276 NSVGAVSASGYLTV----YDPPS----------INLSPNSVNVESGNVARFTCTATGRPE 321
N G AS ++V + PS I + P+S +V G C G+
Sbjct: 61 NGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTLDLNCVVPGQAH 120
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
+ W G P +R + H ++L ++ DS VC V +G
Sbjct: 121 AQVTWHKRGGS---LP--ARHQTHG-------SLLRLHQVTPADS-GEYVCHVVGTSGPL 167
Query: 382 FVRGKLTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ 440
+T+ S P P + S+ T+ C + WY G +L
Sbjct: 168 EASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA 227
Query: 441 NHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
H+ L + +D+G Y C AS+
Sbjct: 228 RHQ---VRGSRLYIFQASPADAGQYVCRASN 255
>EF506611-1|ABP88252.1| 1248|Homo sapiens non-neural L1CAM protein.
Length = 1248
Score = 142 bits (343), Expect = 9e-33
Identities = 135/484 (27%), Positives = 201/484 (41%), Gaps = 37/484 (7%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAG 64
E P I EQ P + V +L C A G P RW + GV + P
Sbjct: 28 EPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHS 87
Query: 65 GLFFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G F + + G+Y C A+N GTA S L + + + + +G+
Sbjct: 88 GSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 147
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIA 182
+VVL C PP + +YW N + L D R+ + GNL + +D Y C A
Sbjct: 148 SVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA 206
Query: 183 RNAAGTR-----ESAIATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDP 229
+ GTR E +K I KP L+ +VA G + +C G P
Sbjct: 207 -HFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 265
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
P + W R +G MP R + +L+L V D+GEY C AENS+G+ + Y+T
Sbjct: 266 TPTIKWLRPSGP--MPADRATYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 323
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
V P P S G AR C GRP+P + W + G I +++D+ +
Sbjct: 324 VEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--R 378
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
+ G +L ++ +D+ T C A N G + V P I+T
Sbjct: 379 IQRGALIL--SNVQPSDTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYM 432
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
S A C A P P + W E G ++Q+ R +GTL ++DL +D+G Y C
Sbjct: 433 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 492
Query: 468 VASS 471
+A++
Sbjct: 493 LAAN 496
Score = 132 bits (320), Expect = 6e-30
Identities = 160/609 (26%), Positives = 240/609 (39%), Gaps = 71/609 (11%)
Query: 21 VTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGG-LFFLRATHGRVHS 78
V V + L C S P I W +L + R + G L+F HS
Sbjct: 141 VEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHS 200
Query: 79 DAGVYWCEA--TNSYGTARSRNATLHVAVL-----REEFRLEPESKQS----AQGDTVVL 127
D Y C A + + L V R+ L P + S QG +VL
Sbjct: 201 D---YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 257
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
EC+ G P P + W + + D + L + + D G Y+C+A N+ G
Sbjct: 258 ECIA-EGFPTPTIKWLRPSGPM--PADRATYQNHNKTLQLLKVGEEDDGEYRCLAENSLG 314
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPL 246
+ A + + PY + P+ + G + C+V G P P+V WR +
Sbjct: 315 SARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAK 373
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
+ + G+L L NV +D CEA N G + A+ Y+ V P+ L+ ++ +
Sbjct: 374 DQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMA 433
Query: 307 --GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G+ A C A G P P++ W E T++ +++ A +G L I D N
Sbjct: 434 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LGIRDLQAN 485
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ C A N + + L VT IT GP + S F C A
Sbjct: 486 DT-GRYFCLAANDQNNVTIMANLKVTDATQ-----ITQGPRSTIEKKGSRVTFTCQASFD 539
Query: 425 P--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 540 PSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRA 599
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILG 537
LLV V S PGP + + H +T + V +SWS ++ I
Sbjct: 600 QLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED-HNAPIEK 642
Query: 538 YQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
Y +E +E G W + + +QT +K L P + Y F V N +G
Sbjct: 643 YDIEFEDKEMAPGK--------WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPG 693
Query: 597 GPSPVSDSV 605
PSPVS++V
Sbjct: 694 EPSPVSETV 702
Score = 115 bits (277), Expect = 9e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 321 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 380
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 381 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 435
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 436 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 492
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 493 LAANDQ-NNVTIMANLKVTDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 550
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 551 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 607
Score = 40.7 bits (91), Expect = 0.031
Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+++ + YE + + +G + + +D P P + ILN++ V +KW
Sbjct: 770 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 829
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-----QATSLIMTNLTSGVSYSV 808
P +L G + GYNV W + K H TS+I++ L SY +
Sbjct: 830 PVDLAQVKGHLRGYNVTY-WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 888
Query: 809 QIAAETIIGLGPFSQ 823
++ A G GP S+
Sbjct: 889 EVQAFNGRGSGPASE 903
>AJ277892-2|CAD12456.1|30017|Homo sapiens Titin protein.
Length = 30000
Score = 141 bits (342), Expect = 1e-32
Identities = 138/492 (28%), Positives = 199/492 (40%), Gaps = 32/492 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E PY IE V +PATL C+ G+P I WYK + S + + L
Sbjct: 7945 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 8004
Query: 70 RATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
+ HSD G Y C+A NS G A S + L F + + G V E
Sbjct: 8005 -VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFE 8063
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
C GS V W K+G L D + + V L I Q+ G+Y C A N G
Sbjct: 8064 CRI-NGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLG 8122
Query: 188 TRES-AIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241
T S A L H + P+ P V G S TF+C V G + W R G
Sbjct: 8123 TASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPG 8182
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSP 299
GN + V+ + +L + V D G+Y+C A N G S S +L V +PP L P
Sbjct: 8183 GNYKMTLVE--NTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAHLGVQEPPRFIKKLEP 8240
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ + V+ R+ C G PE + W + K+ + V D V VL ++
Sbjct: 8241 SRI-VKQDEFTRYECKIGGSPEIKVLWYKDETEI-----QESSKFRMSFV-DSVAVLEMH 8293
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FP 418
+ DS C A N AGS+ L V + PPI P + +K V
Sbjct: 8294 NLSVEDS-GDYTCEAHNAAGSASSSTSLKV-----KEPPIFRKKP-HPIETLKGADVHLE 8346
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRHGK 475
C TP ++WY + L + + ++ L + ++D +D G Y C A++ G
Sbjct: 8347 CELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS 8406
Query: 476 YVWSGALLVDSP 487
G++ + +P
Sbjct: 8407 DTCVGSIALKAP 8418
Score = 138 bits (334), Expect = 1e-31
Identities = 117/463 (25%), Positives = 193/463 (41%), Gaps = 23/463 (4%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C+ GGSP + WYK + + + + L H D+G Y CEA N+ G
Sbjct: 8254 CKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM-HNLSVEDSGDYTCEAHNAAG 8312
Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
+A S + +L V FR +P ++ +G V LEC +G+P +V W K+ + L
Sbjct: 8313 SASS-STSLKVKE-PPIFRKKPHPIETLKGADVHLEC-ELQGTPPFHVSWYKDKRELR-S 8368
Query: 153 GDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
G + + ++ I + D G YQC A N G+ ++ + ++ + P + D
Sbjct: 8369 GKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS-DTCVGSIALKAPPRFVKKLSD 8427
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLRLDNVILADE 267
+ G V Q + G V+W + G + + + +L+ V A+
Sbjct: 8428 ISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANA 8487
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
G+Y+C+ +N G L+V +P +I P S+ V +G+ CT G PE + W
Sbjct: 8488 GKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWF 8547
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
+G ++ D + + F+ V+ L I + +DS N G L
Sbjct: 8548 KDGKE------LTSDNKYKISFFNKVSGLKIINVAPSDS-GVYSFEVQNPVGKDSCTASL 8600
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
V+ D PP T S V C +P ++W+ EG + + T
Sbjct: 8601 QVS--DRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTT 8658
Query: 448 ---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
N L + L++SDSG YTC+A++ G S L V P
Sbjct: 8659 LTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREP 8701
Score = 138 bits (334), Expect = 1e-31
Identities = 136/536 (25%), Positives = 219/536 (40%), Gaps = 30/536 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T E P +++P + V T G+P ++ W+KG +V ++
Sbjct: 8696 LTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDS 8755
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDT 124
+ L S +G Y C +N G A + T H+ + +F +G
Sbjct: 8756 VAELELFDVDT-SQSGEYTCIVSNEAGKA---SCTTHLYIKAPAKFVKRLNDYSIEKGKP 8811
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIAR 183
++LE G+P +V WKKNG + + + L I + DAG+Y C
Sbjct: 8812 LILEG-TFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIE 8870
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
NA+G ++S A + I PY + E V G S + QC++ G P V W + G
Sbjct: 8871 NASG-KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYK--GDTK 8927
Query: 244 M-PLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSIN 296
+ P K+ + +L + V + D GEY C+AENSVG VSAS +LTV + PPS +
Sbjct: 8928 LRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFS 8987
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
V G F C +G ++ W +G P + T+ D L
Sbjct: 8988 RQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQ------TSFLDNTATL 9041
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
I TD++ C+A N GS+ +L +T + + PP + + A
Sbjct: 9042 NIFKTDRS-LAGQYSCTATNPIGSASSSARLILT--EGKNPPFFDIRLAPVDAVVGESAD 9098
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRH 473
F C T ++W + + + ++ N L + +DK DSG YTC A +
Sbjct: 9099 FECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEV 9158
Query: 474 GKYVWSGALLVDSPINPNIHFFRAAD-VSSLPGPPTKPITHNVTDTSVTLSWSQNN 528
GK + L + + P R ++ V G K +T++W +NN
Sbjct: 9159 GKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNN 9214
Score = 137 bits (332), Expect = 2e-31
Identities = 133/499 (26%), Positives = 208/499 (41%), Gaps = 38/499 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V++ E PY + + + A +L C+ G+P + WYKG DT P
Sbjct: 7000 VSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKG------DTKLRPTPEYR 7053
Query: 66 LFFLR--AT--HGRVH-SDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQS 119
+F AT +V+ +D+G Y C+A NS GTA S+ + L F + + +
Sbjct: 7054 TYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQ 7113
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRY 178
G V L C GS V W ++G L D + + VD L I + +G+Y
Sbjct: 7114 TVGLPVTLTCRL-NGSAPIQVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQY 7172
Query: 179 QCIARNAAGTRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
C A N GT S+ K P+ P + G S F+C V G + W
Sbjct: 7173 SCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWS 7232
Query: 237 RS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ GGN + V + LR+ V D G+Y+C+A N VG S L+V +P
Sbjct: 7233 KDNKEIRPGGNYTITCVG--NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 7290
Query: 293 PS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P + S + G + C +G PE + W N + + KY+ + + +
Sbjct: 7291 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWF--RNDSELHESW---KYNMSFI-N 7344
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
V +LTIN+ DS +C A N G + LTV + PP+ T PS
Sbjct: 7345 SVALLTINEASAEDS-GDYICEAHNGVGDASCSTALTV-----KAPPVFTQKPSPVGALK 7398
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCV 468
S + C TP + W + + + + + +T+ D +L + +L+ SD G Y C
Sbjct: 7399 GSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCK 7458
Query: 469 ASSRHGKYVWSGALLVDSP 487
A++ G S ++ P
Sbjct: 7459 ATNEVGSDTCSCSVKFKEP 7477
Score = 137 bits (332), Expect = 2e-31
Identities = 136/532 (25%), Positives = 214/532 (40%), Gaps = 32/532 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E I+E+P + V TL C G+P + +W+K G + SD I + L
Sbjct: 8511 EPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGL 8570
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVL 127
+ + SD+GVY E N G S A+L V+ + F + + G +VV+
Sbjct: 8571 KIIN-VAPSDSGVYSFEVQNPVG-KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVM 8628
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAA 186
EC GSP +V W G + + L D L + ++D+G Y CIA N A
Sbjct: 8629 EC-KVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMA 8687
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ E + A L + P + P+ + TG++VTF V G P V W + + +P
Sbjct: 8688 GSDECS-APLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGS-SELVPG 8745
Query: 247 GRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
R V L+D L L +V + GEY+C N G S + +L + P N +
Sbjct: 8746 DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYS 8805
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
+E G T TG P ++ W G + +A+ + + T+ D +
Sbjct: 8806 IEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILE-IPSSTVEDAGQ 8864
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
+ C N +G ++ + PP + + A C
Sbjct: 8865 YN------CYIENASGKDSCSAQILILE-----PPYFVKQLEPVKVSVGDSASLQCQLAG 8913
Query: 424 TPEPIIAWYFEGEALI------QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
TPE ++WY +G+ + + H RN N TLV +D +DSG Y C A + G+
Sbjct: 8914 TPEIGVSWY-KGDTKLRPTTTYKMHFRN--NVATLVFNQVDINDSGEYICKAENSVGEVS 8970
Query: 478 WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
S L V P + DV G P +++SW ++ K
Sbjct: 8971 ASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGK 9022
Score = 127 bits (307), Expect = 2e-28
Identities = 127/507 (25%), Positives = 203/507 (40%), Gaps = 24/507 (4%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
+ C+ GSP ++ W+ G + S L + SD+G Y C ATN
Sbjct: 8628 MECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCAL-TVNMLEESDSGDYTCIATNM 8686
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
G+ +A L V F +P+ G V + +G+P +V W K L+
Sbjct: 8687 AGSDEC-SAPLTVRE-PPSFVQKPDPMDVLTGTNVTFTSIV-KGTPPFSVSWFKGSSELV 8743
Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ L D L + D + +G Y CI N AG + S L I +
Sbjct: 8744 PGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAG-KASCTTHLYIKAPAKFVKRLN 8802
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD---DGSLRLDNVILAD 266
D + G + + G P V W+++ G P R + L + + + D
Sbjct: 8803 DYSIEKGKPLILEGTFTGTPPISVTWKKN-GINVTPSQRCNITTTEKSAILEIPSSTVED 8861
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
G+Y+C EN+ G S S + + +PP V V G+ A C G PE + W
Sbjct: 8862 AGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSW 8921
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
+G+ T + P + K H + V L N D NDS +C A N G V
Sbjct: 8922 -YKGD-TKLRP-TTTYKMHFR---NNVATLVFNQVDINDS-GEYICKAENSVGE--VSAS 8972
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRN 445
+T + + PP + + + VF C AI EPI ++WY +G+ L +
Sbjct: 8973 TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGKPLKDSPNVQ 9031
Query: 446 VT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502
+ N TL + D+S +G Y+C A++ G S L++ NP R A V +
Sbjct: 9032 TSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDA 9091
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNK 529
+ G H + +SW+++++
Sbjct: 9092 VVGESADFECHVTGTQPIKVSWAKDSR 9118
Score = 124 bits (298), Expect = 3e-27
Identities = 129/507 (25%), Positives = 210/507 (41%), Gaps = 26/507 (5%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E IIE+P +TV P L C G+P + +W+K G + +D+ I + L
Sbjct: 7570 EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASL 7629
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVL 127
+ + SD G+Y E NS G + ++HV+ ++ F + + + G +VVL
Sbjct: 7630 KIPCAEM-SDKGLYSFEVKNSVGKSNC-TVSVHVSDRIVPPSFIRKLKDVNAILGASVVL 7687
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAA 186
EC GS +V W ++G ++ + + L + +D G Y C+A N A
Sbjct: 7688 ECRVS-GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVA 7746
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ E + A L + P P+ V G S+TF + G P V W + + +P
Sbjct: 7747 GSDECS-AVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE-LVPG 7804
Query: 247 GRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
+ L+D L L V + G+YSC N G+ S + +L V +P + +
Sbjct: 7805 ESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFS 7864
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
VE+G+ T TG P ++ W ++ I S+ + + + + T+L I ++
Sbjct: 7865 VETGSPIVLEATYTGTPPISVSW-IKDEYLI-----SQSERCSITMTEKSTILEILESTI 7918
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D C N AG ++V PP + I A C
Sbjct: 7919 EDYAQ-YSCLIENEAGQDICEALVSVLE-----PPYFIEPLEHVEAVIGEPATLQCKVDG 7972
Query: 424 TPEPIIAWYFEGEAL--IQNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
TPE I+WY E L ++ N+ +LV+ +D SD G Y+C A + G S
Sbjct: 7973 TPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSA 8032
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPP 507
L++ P + DV G P
Sbjct: 8033 VLVIKERKLPPFFARKLKDVHETLGFP 8059
Score = 122 bits (293), Expect = 1e-26
Identities = 124/467 (26%), Positives = 186/467 (39%), Gaps = 30/467 (6%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C GS +I+W+K + + FL + +D+G Y C ATN
Sbjct: 5621 LECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLE-GTDSGTYTCSATNK 5679
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
G + H+ V + +E Q +T V G+ + W K+ + L
Sbjct: 5680 AG---HNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKEL- 5735
Query: 151 FDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
G +R D +L + A+ TD+G Y C N GT S ATL + P I P
Sbjct: 5736 HSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSK-ATLFVKEPPQFIKKP 5794
Query: 209 EDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN-MPLGRVKVLDD-GSLRLDNVILA 265
V V + G S TF+C++ G P V W + + +D + ++ +
Sbjct: 5795 SPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVE 5854
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+ G Y CEA N G S S L V +PP+ V V + C TG P +
Sbjct: 5855 NSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVT 5914
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT--DKNDSRNTIVCSAVNYAGSSFV 383
W ++ NR I S KY T D V+V ++ T D +D+ C N GS
Sbjct: 5915 W-LKNNREI----RSSKKYTLT---DRVSVFNLHITKCDPSDT-GEYQCIVSNEGGSCSC 5965
Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-- 441
++ + + PP N T +KS A F T +P I W + + L ++
Sbjct: 5966 STRVAL-----KEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDN 6020
Query: 442 -HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ V + TL ++ +D SG YTC A + G LLV P
Sbjct: 6021 VYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEP 6067
Score = 122 bits (293), Expect = 1e-26
Identities = 127/492 (25%), Positives = 206/492 (41%), Gaps = 25/492 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T E P + P V V T G+P ++W+KG +V +I
Sbjct: 7755 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF 7814
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124
+ L + ++G Y C TN G+A + T H+ V ++ + S + G
Sbjct: 7815 VTELELFEVQP-LESGDYSCLVTNDAGSA---SCTTHLFVKEPATFVKRLADFSVETGSP 7870
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
+VLE G+P +V W K+ + + + + ++ I ++ D +Y C+
Sbjct: 7871 IVLEATYT-GTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIE 7929
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGG 242
N AG ++ A + + PY I E V A G T QC+V G P + W +
Sbjct: 7930 NEAG-QDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLR 7988
Query: 243 NMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
+ P +++ ++ SL ++ V +D GEYSC+A+NSVGAV++S L + + PP
Sbjct: 7989 SAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKERKLPPFFARK 8048
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V+ G F C G + W +G ++ + D T+ V L I
Sbjct: 8049 LKDVHETLGFPVAFECRINGSEPLQVSWYKDG---VL---LKDDANLQTSFVHNVATLQI 8102
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
TD++ CSA N G++ KL ++ + PP P + L + F
Sbjct: 8103 LQTDQSHI-GQYNCSASNPLGTASSSAKLILS--EHEVPPFFDLKPVSVDLALGESGTFK 8159
Query: 419 CTAICTPEPIIAWYFEGEALIQ--NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
C T I W + + N++ V N TL + + K D+G YTC AS+ GK
Sbjct: 8160 CHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGK 8219
Query: 476 YVWSGALLVDSP 487
S L V P
Sbjct: 8220 DSCSAHLGVQEP 8231
Score = 121 bits (292), Expect = 1e-26
Identities = 125/497 (25%), Positives = 190/497 (38%), Gaps = 29/497 (5%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E PY +E+P V + L GG+ I+W+K + S RS+
Sbjct: 5688 HLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDD 5747
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L + +D+G Y C+ +N GTA S+ ATL V + + G +
Sbjct: 5748 TSTSLELFAAKA-TDSGTYICQLSNDVGTATSK-ATLFVKEPPQFIKKPSPVLVLRNGQS 5805
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIAR 183
EC G+P+ V W +G + + +DG I AR ++G Y C AR
Sbjct: 5806 TTFEC-QITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEAR 5864
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
N AGT +I LK+ P I + V S V +C V G P +V W R
Sbjct: 5865 NDAGTASCSI-ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIR 5923
Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
L RV V +L + +D GEY C N G+ S S + + +PPS
Sbjct: 5924 SSKKYTLTDRVSVF---NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKK 5980
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ + A F T G P ++ W + + D + D V L I
Sbjct: 5981 IENTTTVLKSSATFQSTVAGSPPISITWLKDDQI------LDEDDNVYISFVDSVATLQI 6034
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
D N C A N +G L V P I+ S K
Sbjct: 6035 RSVD-NGHSGRYTCQAKNESGVERCYAFLLV----QEPAQIVEKAKSVDVTE-KDPMTLE 6088
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
C TPE + W +G+ ++ + +++ N + ++ + K DSG YT + G
Sbjct: 6089 CVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGS 6148
Query: 476 YVWSGAL-LVDSPINPN 491
L ++D I P+
Sbjct: 6149 SSCDAYLRVLDQNIPPS 6165
Score = 121 bits (291), Expect = 2e-26
Identities = 124/492 (25%), Positives = 205/492 (41%), Gaps = 25/492 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T E P +++P + V + T G+P + W++G +V +I
Sbjct: 6814 LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDT 6873
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124
+ L + + S +G Y C +N+ G A + T + V L+ S S + G +
Sbjct: 6874 VAELELFNIDI-SQSGEYTCVVSNNAGQA---SCTTRLFVKEPAAFLKRLSDHSVEPGKS 6929
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
++LE G+ +V WKK+G + + + ++ I ++ + DAG+Y C
Sbjct: 6930 IILES-TYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIE 6988
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGG 242
N AG R+ A + PY +T E + A G SV+ QC+V G P V W +
Sbjct: 6989 NEAG-RDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLR 7047
Query: 243 NMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
P R ++ +L + V + D GEY+C+AENS+G S+ + + PPS
Sbjct: 7048 PTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQ 7107
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ G TC G + W +G ++ + D+ T+ D V L I
Sbjct: 7108 LKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDG---VL---LRDDENLQTSFVDNVATLKI 7161
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
TD + S CSA N G++ +L T+ + + P P + + A F
Sbjct: 7162 LQTDLSHS-GQYSCSASNPLGTASSSARL--TAREPKKSPFFDIKPVSIDVIAGESADFE 7218
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
C I W + + + +T N L + + K DSG YTC A++ GK
Sbjct: 7219 CHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGK 7278
Query: 476 YVWSGALLVDSP 487
+ S L V P
Sbjct: 7279 DMCSAQLSVKEP 7290
Score = 117 bits (281), Expect = 3e-25
Identities = 125/490 (25%), Positives = 212/490 (43%), Gaps = 35/490 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLR 70
P +++ D++ + L G+ ++ W+K G +V + I + + L+
Sbjct: 8419 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQ 8478
Query: 71 ATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLE 128
+ RV ++AG Y C+ N G ATL +VL +E PES + GDT LE
Sbjct: 8479 FS--RVEPANAGKYTCQIKNDAGMQECF-ATL--SVLEPATIVEKPESIKVTTGDTCTLE 8533
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
C G+PE + W K+G+ L D ++ + L I + +D+G Y +N G
Sbjct: 8534 CTVA-GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVG 8592
Query: 188 TRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
++S A+L++ + P ++ +GSSV +C+V G P V W G +
Sbjct: 8593 -KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHE--GNEI 8649
Query: 245 PLGRV--KVLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
GR L D + L +L +D G+Y+C A N G+ S LTV +PPS P+
Sbjct: 8650 SSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPD 8709
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
++V +G FT G P ++ W +G+ ++ PG D+ + ++ D V L + D
Sbjct: 8710 PMDVLTGTNVTFTSIVKGTPPFSVSW-FKGSSELV-PG---DRCN-VSLEDSVAELELFD 8763
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
D + S C N AG + L + + P ++ ++ + T
Sbjct: 8764 VDTSQS-GEYTCIVSNEAGKASCTTHLYI-----KAPAKFVKRLNDYSIEKGKPLILEGT 8817
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYV 477
TP + W G + + R N+T + ++ S D+G Y C + GK
Sbjct: 8818 FTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDS 8877
Query: 478 WSGALLVDSP 487
S +L+ P
Sbjct: 8878 CSAQILILEP 8887
Score = 116 bits (280), Expect = 4e-25
Identities = 114/486 (23%), Positives = 190/486 (39%), Gaps = 22/486 (4%)
Query: 10 EAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
E P +++ VA+ + L C+ GSP + W++ + ++ +
Sbjct: 7289 EPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVAL 7348
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
L D+G Y CEA N G A A A F +P + +G V+L+
Sbjct: 7349 LTINEASAE-DSGDYICEAHNGVGDASCSTALTVKAP--PVFTQKPSPVGALKGSDVILQ 7405
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAG 187
C G+P V W K+ + + ++ +L I + +D G Y C A N G
Sbjct: 7406 C-EISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVG 7464
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMP 245
+ ++ ++K P + D G +V + V G V+W + G
Sbjct: 7465 S-DTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESE 7523
Query: 246 LGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
R+ +D+ +L+L + ++ G+Y C+ +N G S LTV +P I P + V
Sbjct: 7524 NTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTV 7583
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+GN C TG PE + W +G +S D H + V L I + +
Sbjct: 7584 TTGNPFALECVVTGTPELSAKWFKDGRE------LSADSKHHITFINKVASLKIPCAEMS 7637
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D + N G S ++V D PP + + + V C +
Sbjct: 7638 D-KGLYSFEVKNSVGKS--NCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGS 7694
Query: 425 PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
+ W+ +G ++ + + N TL L L+ SD+G YTCVA++ G S
Sbjct: 7695 APISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAV 7754
Query: 482 LLVDSP 487
L V P
Sbjct: 7755 LTVQEP 7760
Score = 115 bits (277), Expect = 9e-25
Identities = 125/481 (25%), Positives = 192/481 (39%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E PY ++Q V V+ A+L C+ G+P + WYKG + T + + L
Sbjct: 8886 EPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 8945
Query: 70 RATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
+ +D+G Y C+A NS G + S T+ L F + Q G VV +
Sbjct: 8946 VFNQVDI-NDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFD 9004
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
C GS +V W K+G+ L + + +D L I ++ AG+Y C A N G
Sbjct: 9005 C-AISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIG 9063
Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241
+ S+ + K P+ V A G S F+C V G V W R G
Sbjct: 9064 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSG 9123
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
G + ++ + L + V D G+Y+C A N VG S + L + + PPS
Sbjct: 9124 GKYQISYLE--NSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKR 9181
Query: 299 -PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
+V GN + G T+ W N I P + + + VL
Sbjct: 9182 LSETVEETEGNSFKLEGRVAGSQPITVAW--YKNNIEIQPTSNCE----ITFKNNTLVLQ 9235
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+ ND+ C N AGS+ + + + + PP+ + T+
Sbjct: 9236 VRKAGMNDA-GLYTCKVSNDAGSALCTSSIVI--KEPKKPPVFDQHLTPVTVSEGEYVQL 9292
Query: 418 PCTAICTPEPI-IAWYFEGEALIQNHRRNVT-NDGTLV--LKDLDKSDSGTYTCVASSRH 473
C + EPI I W G + + R + + GT V L+D+ K+DSG Y C AS+
Sbjct: 9293 SC-HVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVA 9351
Query: 474 G 474
G
Sbjct: 9352 G 9352
Score = 115 bits (276), Expect = 1e-24
Identities = 121/518 (23%), Positives = 203/518 (39%), Gaps = 27/518 (5%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
D ++ + +P L G+P ++ W K G+ V +I L V D
Sbjct: 8803 DYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVE-D 8861
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEP 138
AG Y C N+ G + + + +L + ++ E + + GD+ L+C G+PE
Sbjct: 8862 AGQYNCYIENASG---KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQC-QLAGTPEI 8917
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG--TRESAIAT 195
V W K L +MH + LV D+G Y C A N+ G + + +
Sbjct: 8918 GVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTV 8977
Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDD 254
+ + P DV G V F C + G V W + + P + LD+
Sbjct: 8978 QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDN 9037
Query: 255 -GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNVA 310
+L + + G+YSC A N +G+ S+S L + + PP ++ V+ G A
Sbjct: 9038 TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESA 9097
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
F C TG + W+ + +R I S KY + + + LT+ DK DS
Sbjct: 9098 DFECHVTGTQPIKVSWAKD-SREI----RSGGKYQISYL-ENSAHLTVLKVDKGDS-GQY 9150
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-I 429
C AVN G +L + + PP T S + + + +PI +
Sbjct: 9151 TCYAVNEVGKDSCTAQLNIK--ERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITV 9208
Query: 430 AWYFEGEALIQNHRRNVT-NDGTLVL--KDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
AWY + +T + TLVL + +D+G YTC S+ G + + ++++
Sbjct: 9209 AWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE 9268
Query: 487 PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
P P + V+ G + H + + W
Sbjct: 9269 PKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQW 9306
Score = 114 bits (275), Expect = 2e-24
Identities = 126/486 (25%), Positives = 197/486 (40%), Gaps = 40/486 (8%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V AP I + + VA A C +P+ +W+K G + SI +
Sbjct: 4377 VVKRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKY 4436
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDT 124
+ L +V D G Y C+A+N YG+ S ATL V F P+S + G
Sbjct: 4437 ISSLEILRTQV-VDCGEYTCKASNEYGSV-SCTATLTVTEAYPPTFLSRPKSLTTFVGKA 4494
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTL-------LFDGDSRMHLVDGGNLVIQDARQTDAGR 177
C G+P W+K+G L + D +++ H+++ NL IQ D G
Sbjct: 4495 AKFIC-TVTGTPVIETIWQKDGAALSPSPNWKISDAENK-HILELSNLTIQ-----DRGV 4547
Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
Y C A N G + A L I KP+ I E V + V +C+V D V W
Sbjct: 4548 YSCKASNKFGA-DICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTW-- 4604
Query: 238 SAGGGNMPLGR-VKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
S G +P G+ K+ +D +L + L D G Y C A N G+ S S +TV +PP
Sbjct: 4605 SKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPP 4664
Query: 294 S-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
S + S + G AR C G P + W + N+ +S +
Sbjct: 4665 SFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTW-FKNNKE-----LSESNTVRMYFVNS 4718
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
+L I D DS + C AVN GS ++ + + PP +
Sbjct: 4719 EAILDITDVKVEDS-GSYSCEAVNDVGSDSCSTEIVI-----KEPPSFIKTLEPADIVRG 4772
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSGTYTCVA 469
+ A+ C T I+W+ + + + + + + + +LV ++ + +D G Y CV
Sbjct: 4773 TNALLQCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVV 4832
Query: 470 SSRHGK 475
++ GK
Sbjct: 4833 ANEVGK 4838
Score = 114 bits (274), Expect = 2e-24
Identities = 125/493 (25%), Positives = 194/493 (39%), Gaps = 37/493 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P P V ++ +L C G+P + WYK + S I +
Sbjct: 6442 EPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSI 6501
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
+ SD G Y C+A N G+ + + L+E F + S G+ L
Sbjct: 6502 HILNVDT-SDIGEYHCKAQNEVGS----DTCVCTVKLKEPPRFVSKLNSLTVVAGEPAEL 6556
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDG-GNLVIQDARQTDAGRYQCIARNA 185
+ G+ V W K + ++ + ++ R+ V+ L A +AG+Y C +N
Sbjct: 6557 QA-SIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKND 6615
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ +ATL + ++ + G + T +C+V G P V W + G +
Sbjct: 6616 GGMEEN-MATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKD---GKLL 6671
Query: 246 LGRVK-----VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINL 297
K SLR+ +V D G Y+ + +N+VG S + + V D PPS
Sbjct: 6672 TSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTR 6731
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
+ G C G ++ W E + + S KY T D V L
Sbjct: 6732 RLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIV-----SGAKYQ-TTFSDNVCTLQ 6785
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+N D +D N C A N AGS R LTV PP + + LP K++ F
Sbjct: 6786 LNSLDSSDMGN-YTCVAANVAGSDECRAVLTV----QEPPSFVKEPEPLEVLPGKNV-TF 6839
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHG 474
TP + W+ L++ R N+ + T L L ++D S SG YTCV S+ G
Sbjct: 6840 TSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG 6899
Query: 475 KYVWSGALLVDSP 487
+ + L V P
Sbjct: 6900 QASCTTRLFVKEP 6912
Score = 113 bits (272), Expect = 4e-24
Identities = 120/456 (26%), Positives = 178/456 (39%), Gaps = 27/456 (5%)
Query: 43 IRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG-TARSRNATL 101
+ WY LV SD L + L G Y CEA N G TA S T+
Sbjct: 4318 VNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTV 4377
Query: 102 HVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL-FDGDSRMHLV 160
V + + E + A G C + +P W K G+ + D S
Sbjct: 4378 -VKRAAPVIKRKIEPLEVALGHLAKFTC-EIQSAPNVRFQWFKAGREIYESDKCSIRSSK 4435
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSS 218
+L I + D G Y C A N G+ S ATL + P ++ P+ + G +
Sbjct: 4436 YISSLEILRTQVVDCGEYTCKASNEYGS-VSCTATLTVTEAYPPTFLSRPKSLTTFVGKA 4494
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAE 275
F C V G P+ + +W++ G P K+ D + L L N+ + D G YSC+A
Sbjct: 4495 AKFICTVTGTPVIETIWQKD-GAALSPSPNWKISDAENKHILELSNLTIQDRGVYSCKAS 4553
Query: 276 NSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
N GA L + D P V C + T+ WS +G + +
Sbjct: 4554 NKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQK--L 4611
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
PG K + D + L I DS T VC+A N AGSS +TV
Sbjct: 4612 PPG----KDYKICFEDKIATLEIPLAKLKDS-GTYVCTASNEAGSSSCSATVTVR----E 4662
Query: 396 PPPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGT 451
PP + PS LP +S A C +P + W+ + L +++ V ++
Sbjct: 4663 PPSFVKKVDPSYLMLPGES-ARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAI 4721
Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
L + D+ DSG+Y+C A + G S +++ P
Sbjct: 4722 LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEP 4757
Score = 108 bits (259), Expect = 1e-22
Identities = 121/490 (24%), Positives = 190/490 (38%), Gaps = 30/490 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P +++ D+ Q TL GS ++ W KG ++ D + + G+ L
Sbjct: 4849 EPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVL 4908
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVL 127
++ S G Y C A N G+ S + +++E ++ E Q GD L
Sbjct: 4909 IIPDVQI-SFGGKYTCLAENEAGSQTS----VGELIVKEPAKIIERAELIQVTAGDPATL 4963
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
E G+PE W K+G+ L+ R+ + L A D+G+Y N
Sbjct: 4964 E-YTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEV 5022
Query: 187 GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
G+ E+ L I P+ +V + + C++ G V W + G
Sbjct: 5023 GSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKD-GKEIA 5081
Query: 245 PLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
R ++ SL + V + D G ++C A NSVG+ +SG L V +PPS P S
Sbjct: 5082 ASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGS 5141
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+V G+ T G T+ W +GN+ ++ G Y + L + T
Sbjct: 5142 KDVLPGSAVCLKSTFQGSTPLTIRW-FKGNKELVSGGSC---YITKEALESSLELYLVKT 5197
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
+DS T C N AG L V P + +Q L C
Sbjct: 5198 --SDS-GTYTCKVSNVAGGVECSANLFV----KEPATFVEKLEPSQLLKKGDATQLACKV 5250
Query: 422 ICTPEPIIAWYFEGEALIQN--HRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
TP I W+ + ++ HR + V + L L D+ DSG Y C A + G
Sbjct: 5251 TGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHC 5310
Query: 479 SGALLV-DSP 487
S ++V +SP
Sbjct: 5311 SSIVIVKESP 5320
Score = 107 bits (257), Expect = 2e-22
Identities = 113/425 (26%), Positives = 183/425 (43%), Gaps = 37/425 (8%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSP 136
S++G Y C+ N G R + + VL +E PE G+ LEC+ G+P
Sbjct: 7544 SNSGKYICQIKNDAGM---RECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVT-GTP 7599
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
E + W K+G+ L D + ++ +L I A +D G Y +N+ G T
Sbjct: 7600 ELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSN---CT 7656
Query: 196 LKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
+ +H+ P I +DV A G+SV +CRV G V W + GN + K
Sbjct: 7657 VSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQD---GNEIVSGPK 7713
Query: 251 VLDDGS-----LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
S L L + +D G Y+C A N G+ S LTV +PPS +P+SV V
Sbjct: 7714 CQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVL 7773
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G FT G P + W +G+R ++ PG S + ++ D VT L + + +
Sbjct: 7774 PGMSLTFTSVIRGTPPFKVKW-FKGSRELV-PGESCN----ISLEDFVTELELFEVQPLE 7827
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
S C N AGS+ L V + P ++ ++ S V T TP
Sbjct: 7828 S-GDYSCLVTNDAGSASCTTHLFV-----KEPATFVKRLADFSVETGSPIVLEATYTGTP 7881
Query: 426 EPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKS--DSGTYTCVASSRHGKYVWSGAL 482
++W + + Q+ R ++T + + +L+ L+ + D Y+C+ + G+ + +
Sbjct: 7882 PISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALV 7941
Query: 483 LVDSP 487
V P
Sbjct: 7942 SVLEP 7946
Score = 101 bits (243), Expect = 1e-20
Identities = 121/511 (23%), Positives = 186/511 (36%), Gaps = 32/511 (6%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C+ GS ++ W+ +VS + + L+ + SD G Y C A N
Sbjct: 6746 LECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL-NSLDSSDMGNYTCVAANV 6804
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
G+ R A L V F EPE + G V + RG+P V W + + L+
Sbjct: 6805 AGSDECR-AVLTVQE-PPSFVKEPEPLEVLPGKNVTFTSVI-RGTPPFKVNWFRGARELV 6861
Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
++ D L + + + +G Y C+ N AG + S L + +
Sbjct: 6862 KGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG-QASCTTRLFVKEPAAFLKRLS 6920
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR----VKVLDDGSLRLDNVILA 265
D + G S+ + G V W++ G N+ V L + N
Sbjct: 6921 DHSVEPGKSIILESTYTGTLPISVTWKKD--GFNITTSEKCNIVTTEKTCILEILNSTKR 6978
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
D G+YSCE EN G ++ +PP + G+ C G PE T+
Sbjct: 6979 DAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVS 7038
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W +G+ T + P Y + V L N + NDS C A N G++
Sbjct: 7039 W-YKGD-TKLRPTPEYRTYFT----NNVATLVFNKVNINDS-GEYTCKAENSIGTA--SS 7089
Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT---PEPI-IAWYFEGEALIQN 441
K + + PP + Q I+ P T C PI + WY +G L +
Sbjct: 7090 KTVFRIQERQLPPSF----ARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDGVLLRDD 7145
Query: 442 HRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAA 498
V N TL + D S SG Y+C AS+ G S L P +
Sbjct: 7146 ENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPV 7205
Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+ + G H + ++WS++NK
Sbjct: 7206 SIDVIAGESADFECHVTGAQPMRITWSKDNK 7236
Score = 99.1 bits (236), Expect = 8e-20
Identities = 125/504 (24%), Positives = 195/504 (38%), Gaps = 45/504 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFL 69
P Q DV P +C GS ++ WYK G + + S L +
Sbjct: 8984 PSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNI 9043
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF---RLEPESKQSAQGDTVV 126
T S AG Y C ATN G+A S + F RL P + G++
Sbjct: 9044 FKTD---RSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVD--AVVGESAD 9098
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNA 185
EC G+ V W K+ + + G ++ +L + +L + + D+G+Y C A N
Sbjct: 9099 FEC-HVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNE 9157
Query: 186 AGTRESAIATLKIH---IKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGG 241
G ++S A L I I P + V +T G+S + RV G V W ++
Sbjct: 9158 VG-KDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKN-NI 9215
Query: 242 GNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSI 295
P ++ + L++ + D G Y+C+ N G+ + + + +P P
Sbjct: 9216 EIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF 9275
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+ V V G + +C G + W G I P D+ + + G V
Sbjct: 9276 DQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGRE--IKPS---DRC-SFSFASGTAV 9329
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----------IITNGPS 405
L + D K DS + VC A N AGS + K+T+ P + P
Sbjct: 9330 LELRDVAKADSGD-YVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQ 9388
Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDGT---LVLKDLDKSD 461
+ + K+ A F P P + W + L Q R + G L ++D K+D
Sbjct: 9389 SIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTD 9448
Query: 462 SGTYTCVASSRHGKYVWSGALLVD 485
SG Y CVA + HG+ + L VD
Sbjct: 9449 SGLYRCVAFNEHGEIESNVNLQVD 9472
Score = 98.7 bits (235), Expect = 1e-19
Identities = 121/527 (22%), Positives = 194/527 (36%), Gaps = 26/527 (4%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I + DV L CR GS ++ W++ G +VS + + L
Sbjct: 7668 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 7727
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ SD G+Y C A N G+ +A L V F P+S + G ++ +
Sbjct: 7728 SLLEP-SDTGIYTCVAANVAGSDEC-SAVLTVQE-PPSFEQTPDSVEVLPGMSLTFTSVI 7784
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
RG+P V W K + L+ + L D L + + + ++G Y C+ N AG
Sbjct: 7785 -RGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAG--- 7840
Query: 191 SAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
SA T + +K + D +TGS + + G P V W + +
Sbjct: 7841 SASCTTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERC 7900
Query: 249 VKVLDDGSLRLDNV--ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
+ + S L+ + + D +YSC EN G ++V +PP V
Sbjct: 7901 SITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVI 7960
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G PE + W E + P + + V L IN D +D
Sbjct: 7961 GEPATLQCKVDGTPEIRISWYKEHTKLRSAPA------YKMQFKNNVASLVINKVDHSDV 8014
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N G+ V + + + PP + + F C I E
Sbjct: 8015 -GEYSCKADNSVGA--VASSAVLVIKERKLPPFFARKLKDVHETLGFPVAFECR-INGSE 8070
Query: 427 PI-IAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
P+ ++WY +G L + V N TL + D+S G Y C AS+ G S L
Sbjct: 8071 PLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 8130
Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
++ P + V G H + ++W+++N+
Sbjct: 8131 ILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNR 8177
Score = 96.3 bits (229), Expect = 6e-19
Identities = 107/488 (21%), Positives = 186/488 (38%), Gaps = 27/488 (5%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P I++ + T AT GSP +I W K ++ D + I + L
Sbjct: 5973 EPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATL 6032
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVL 127
+ + +G Y C+A N G R L ++E ++ ++K + D + L
Sbjct: 6033 QI-RSVDNGHSGRYTCQAKNESGVERCYAFLL----VQEPAQIVEKAKSVDVTEKDPMTL 6087
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
EC+ G+PE V W K+G+ ++ M + + IQ + D+G+Y N
Sbjct: 6088 ECVVA-GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDF 6146
Query: 187 GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
G+ ++ + L +I P + GSS+ +C+V G W + +
Sbjct: 6147 GSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST 6206
Query: 245 PLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
V + S+ L+ N+ L D Y+C+ N G + SG LTV +PPS + P
Sbjct: 6207 SAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQ 6266
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
+ F G P + W + + P +T+ + +V D
Sbjct: 6267 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSV----DAS 6322
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K C N GS L VT PP + +++ + + C
Sbjct: 6323 KT---GQYTCHVTNDVGSDSCTTMLLVT----EPPKFVKKLEASKIVKAGDSSRLECKIA 6375
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
+PE + W+ L + + +T + + + +L DSG + C A + G S
Sbjct: 6376 GSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCS 6435
Query: 480 GALLVDSP 487
++V P
Sbjct: 6436 TKVIVKEP 6443
Score = 95.1 bits (226), Expect = 1e-18
Identities = 125/526 (23%), Positives = 204/526 (38%), Gaps = 32/526 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFF 68
E P + + +TV +PA L G+ ++W K V+ ++ I +
Sbjct: 6535 EPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVAT 6594
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
L+ ++AG Y C+ N G + ATL VL +E + G+T L
Sbjct: 6595 LQFAKAEP-ANAGKYICQIKNDGGMEENM-ATL--MVLEPAVIVEKAGPMTVTVGETCTL 6650
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
EC G+PE +V W K+G+ L + + +L I + DAG Y +N
Sbjct: 6651 EC-KVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNV 6709
Query: 187 GTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
G + S A + + + P ++ G+S +C+V G V W
Sbjct: 6710 G-KSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIV 6768
Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
D +L+L+++ +D G Y+C A N G+ LTV +PPS P
Sbjct: 6769 SGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEP 6828
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ V G FT G P + W G R ++ G + Y D V L + +
Sbjct: 6829 LEVLPGKNVTFTSVIRGTPPFKVNW-FRGARELV-KGDRCNIYFE----DTVAELELFNI 6882
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
D + S C N AG + +L V P + + P KS+ + T
Sbjct: 6883 DISQS-GEYTCVVSNNAGQASCTTRLFV----KEPAAFLKRLSDHSVEPGKSI-ILESTY 6936
Query: 422 ICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVW 478
T + W +G + + + N VT + T +L+ L+ K D+G Y+C + G+ V
Sbjct: 6937 TGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDV- 6995
Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
GAL+ S + P + + G +T+SW
Sbjct: 6996 CGALV--STLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSW 7039
Score = 94.7 bits (225), Expect = 2e-18
Identities = 113/472 (23%), Positives = 178/472 (37%), Gaps = 24/472 (5%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+ P+ I++ V A ++ L C+ + W K G + I + L
Sbjct: 4569 DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATL 4628
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
++ D+G Y C A+N G++ S +AT+ V + S G++ L C
Sbjct: 4629 EIPLAKL-KDSGTYVCTASNEAGSS-SCSATVTVREPPSFVKKVDPSYLMLPGESARLHC 4686
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+GSP V W KN + L RM+ V+ ++ I D + D+G Y C A N G+
Sbjct: 4687 -KLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGS 4745
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+S + I P I E G++ QC V G ++ W + +
Sbjct: 4746 -DSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSK-K 4803
Query: 249 VKVLDDGSL---RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++ SL + + AD GEY C N VG + +PP+ + +
Sbjct: 4804 YRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIAL 4863
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G G ++ W ++G I G + + +GV VL I D +
Sbjct: 4864 GGQTVTLQAAVRGSEPISVTW-MKGQEVIREDGKIKMSFS-----NGVAVLIIPDVQISF 4917
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
C A N AGS G+L V P II Q + A T TP
Sbjct: 4918 G-GKYTCLAENEAGSQTSVGELIV----KEPAKIIERAELIQ-VTAGDPATLEYTVAGTP 4971
Query: 426 EPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHG 474
E WY +G L+ + + ++ N L + DSG YT S+ G
Sbjct: 4972 ELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVG 5023
Score = 94.3 bits (224), Expect = 2e-18
Identities = 113/465 (24%), Positives = 176/465 (37%), Gaps = 26/465 (5%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P + +P V L GS IRW+KG +VS I L
Sbjct: 5131 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSL 5190
Query: 70 RATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
+ SD+G Y C+ +N G S N + E +LEP S+ +GD L
Sbjct: 5191 ELYLVKT-SDSGTYTCKVSNVAGGVECSANLFVKEPATFVE-KLEP-SQLLKKGDATQLA 5247
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAG 187
C G+P + W N + + RM V+ ++ + D D+G Y C A+N AG
Sbjct: 5248 C-KVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG 5306
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
+ + + + PY + + V V G P ++ W +
Sbjct: 5307 SDHCSSIVI-VKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRK 5365
Query: 248 RVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
+ D SL++ + AD GEY C N VG+ S +T+ +PPS S +
Sbjct: 5366 YKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSL 5425
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KN 364
G A F T G T+ W + + ++ D + V L ++ + K+
Sbjct: 5426 RGGTAAFQATLKGSLPITVTWLKDSDE------ITEDDNIRMTFENNVASLYLSGIEVKH 5479
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D + VC A N AG L+V + P IT + + A T
Sbjct: 5480 DGK--YVCQAKNDAGIQRCSALLSV-----KEPATITEEAVSIDVTQGDPATLQVKFSGT 5532
Query: 425 PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLK--DLDKSDSGTYT 466
E W+ +G+ L + ++ D +LK +K DSG YT
Sbjct: 5533 KEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT 5577
Score = 94.3 bits (224), Expect = 2e-18
Identities = 116/490 (23%), Positives = 179/490 (36%), Gaps = 23/490 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
VT E P I++ + R A GS + W K + D + +
Sbjct: 5407 VTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENN 5466
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+ L + V D G Y C+A N G R +A L V E S QGD
Sbjct: 5467 VASLYLSGIEVKHD-GKYVCQAKNDAGIQRC-SALLSVKE-PATITEEAVSIDVTQGDPA 5523
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184
L+ + G+ E W K+GQ L ++ + D +++ I + D+G Y +N
Sbjct: 5524 TLQ-VKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQN 5582
Query: 185 AAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
G ++ I L + I P + + + GS + +C V G + W +
Sbjct: 5583 DVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEI 5642
Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
+ D + L + + D G Y+C A N G SG+LTV +PP P
Sbjct: 5643 SASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 5702
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
S +V + G T+ W + + G +R + D T L +
Sbjct: 5703 SQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE--LHSGAARSVWKD----DTSTSLELFA 5756
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
DS T +C N G++ + L V PP I L F C
Sbjct: 5757 AKATDS-GTYICQLSNDVGTATSKATLFV----KEPPQFIKKPSPVLVLRNGQSTTFECQ 5811
Query: 421 AICTPEPIIAWYFEGEAL--IQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
TP+ ++WY +G + IQ H + + T + +SGTY C A + G
Sbjct: 5812 ITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTAS 5871
Query: 478 WSGALLVDSP 487
S L V P
Sbjct: 5872 CSIELKVKEP 5881
Score = 80.6 bits (190), Expect = 3e-14
Identities = 109/520 (20%), Positives = 209/520 (40%), Gaps = 44/520 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
+ C+ GS + +W+K G + + ++ L + + A Y C+ +N
Sbjct: 6183 MECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN-YTCKVSNV 6241
Query: 91 YGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
G +A + ++E F ++P +Q+ TV + + +G+P + W K+
Sbjct: 6242 AGD----DACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAIL-KGTPPFKIKWFKDDVE 6296
Query: 149 LLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
L+ G ++G NL DA +T G+Y C N G+ +S L + P
Sbjct: 6297 LV-SGPKCFIGLEGSTSFLNLYSVDASKT--GQYTCHVTNDVGS-DSCTTMLLVTEPPKF 6352
Query: 205 ITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDGS-LRL 259
+ E + + G S +C++ G P V+W R+ +P R+ +D + +++
Sbjct: 6353 VKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEH--ELPASDKYRMTFIDSVAVIQM 6410
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
+N+ D G++ CEA+N G+ S S + V +PP + P V C +G
Sbjct: 6411 NNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGT 6470
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
P + W + + + K + + +L ++ +D + C A N G
Sbjct: 6471 PPFEVVWYKDKRQ---LRSSKKYKIASKNFHTSIHILNVDTSDIGEYH----CKAQNEVG 6523
Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439
S V + + PP + ++ T+ A + + W E E +I
Sbjct: 6524 SD-----TCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVI 6578
Query: 440 ---QNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFF 495
+N R V N TL + +++G Y C + G L+V + P +
Sbjct: 6579 RESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMEENMATLMV---LEPAVIVE 6635
Query: 496 RAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKIGSSS 534
+A ++ G T + V T +++ W ++ K+ +SS
Sbjct: 6636 KAGPMTVTVG-ETCTLECKVAGTPELSVEWYKDGKLLTSS 6674
Score = 78.2 bits (184), Expect = 2e-13
Identities = 111/491 (22%), Positives = 197/491 (40%), Gaps = 48/491 (9%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G P P V W N +TL + + ++VI++ +++ G Y +A+N AG R+ I
Sbjct: 17477 GKPPPTVTWNMNERTLPQEATIETTAISS-SMVIKNCQRSHQGVYSLLAKNEAGERKKTI 17535
Query: 194 ATLKIHIKPYLITGP---EDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMPLGRV 249
+ + P + P ++ ++ F GG P+ + + +
Sbjct: 17536 IVDVLDV-PGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVT 17594
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDPPSINLSPNSVNVES 306
+ + + +I + AENS+G V S L + +P ++ P + V+
Sbjct: 17595 YTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKE 17654
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT-VLTINDTDKND 365
V + T T T P S N + + +K+H + ++ T+ + D
Sbjct: 17655 --VTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGD 17712
Query: 366 SRNTIVCSAVNYAGS---SFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
+ V SAVN G SF +T D+ PP + + T+ +
Sbjct: 17713 TYEYRV-SAVNIVGQGKPSFCTKPITC-KDELAPPTLHLDFRDKLTIRVGEAFALTGRYS 17770
Query: 423 CTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVWS 479
P+P ++W+ + ++++ R ++ T TL L+ + +SDSG Y V + G
Sbjct: 17771 GKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSR--K 17828
Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGY 538
G F +V PGPP P++ + VT + +SW G S I Y
Sbjct: 17829 G--------------FCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNY 17874
Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
+E +E G + W+ + +T V L+ G Y+F + EN +G+S P
Sbjct: 17875 IIE--KKEV--GKDV------WMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 17924
Query: 599 SPVSDSVTVGD 609
VSDS+ D
Sbjct: 17925 L-VSDSMKAKD 17934
Score = 75.8 bits (178), Expect = 9e-13
Identities = 162/702 (23%), Positives = 278/702 (39%), Gaps = 75/702 (10%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+P +G P P + W K L + D + ++ + DAG+Y N+ G
Sbjct: 20642 VPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGK 20701
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGNMP 245
+E I + + +++ + VT++ + GG P+ + V+ +R A +
Sbjct: 20702 KEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWS 20761
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV-NV 304
+ S R+ N+ + AEN G + G D + +P V ++
Sbjct: 20762 TVTTEC-SKTSFRVANLEEGKSYFFRVFAENEYG-IGDPG--ETRDAVKASQTPGPVVDL 20817
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP-GMSRDKYHATAVFDGVTVLTINDTDK 363
+ +V++ +C+ G +P S G+R I + ++ V ++ L + D
Sbjct: 20818 KVRSVSKSSCSI-GWKKPH---SDGGSRIIGYVVDFLTEENKWQRVMKSLS-LQYSAKDL 20872
Query: 364 NDSRN-TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
+ + T SA N G V DD P + G + K + F
Sbjct: 20873 TEGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIP 20932
Query: 423 CT--PEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGKYV 477
P P ++W + L + R +V + TL++ D KSD+G YT + G
Sbjct: 20933 IKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK- 20991
Query: 478 WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSIL 536
G + + V PG PT PI + VT ++TL W+ G S I
Sbjct: 20992 -EGTISIK--------------VVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEIT 21036
Query: 537 GYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
Y +E R+++ NN WV A V +T + V L G+ Y F V EN +G+
Sbjct: 21037 NYILE--KRDSV--NNK------WVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV- 21085
Query: 597 GPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEIL 656
G S+ + + V ++ N + H + + T D K K +
Sbjct: 21086 GEGLKSEPIVARHPFD-------VPDAPPPPNIVDVRH--DSVSLTWTDPK--KTGGSPI 21134
Query: 657 NFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEG 716
Y+LE F+ +++ + KT + D F++T L + +YEF ++ G
Sbjct: 21135 TGYHLE-----FKERNSLLWKRANKTPIRMRD---FKVTGLTEGLEYEFRVMAINLAGVG 21186
Query: 717 KPS-NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
KPS S LD P PP E+ + +V L W+ P+ +TGY +V D
Sbjct: 21187 KPSLPSEPVVALD--PIDPPGKPEVINITRNSVTLIWTEPKYD-GGHKLTGY--IVEKRD 21241
Query: 776 VPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
+P+ M A + V + + +T+L G Y +I A+ G
Sbjct: 21242 LPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKNTAG 21282
Score = 68.9 bits (161), Expect = 1e-10
Identities = 47/180 (26%), Positives = 90/180 (50%), Gaps = 11/180 (6%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
F L+P S + +G T + L G P P +W +GQ ++ D ++ + + G +L+I
Sbjct: 1459 FVLKPVSFKCLEGQTARFD-LKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLII 1517
Query: 168 QDARQTDAGRYQCIARNAAGTRE-SAIATLKI---HIKPYLITGPEDVVAQTGSSVTFQC 223
A +D+G + +A+N AG S I T++ +KP + ++V + GS + +
Sbjct: 1518 VPATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKV 1577
Query: 224 RVGGDPLPDVLWRRSAG---GGNMPLGRVK-VLDDGSLRLDNVILADEGEYSCEAENSVG 279
R G+P PD++W +++ P R++ + +L++D+ + D Y+ A N G
Sbjct: 1578 RATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATAINKAG 1637
Score = 68.1 bits (159), Expect = 2e-10
Identities = 102/414 (24%), Positives = 171/414 (41%), Gaps = 38/414 (9%)
Query: 92 GTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLF 151
G A S ATL+V EFR + + + + EC P+ V W K+ Q L
Sbjct: 3043 GKATS-TATLYVEARHIEFRKHIKDIKVLEKKRAMFEC--EVSEPDITVQWMKDDQELQI 3099
Query: 152 DGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
++ + L+I R +DAG+Y +A T + + + I+ I
Sbjct: 3100 TDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRS--IKKEVQ 3157
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLR---LDNVILAD 266
V+ + + V F+ V D + D W + N + R K + + + + +D
Sbjct: 3158 VIEKQRAVVEFE--VNEDDV-DAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSD 3214
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
GEY+ A + +V+ Y+ +PP + V V+SG ARF +GRP+P + W
Sbjct: 3215 AGEYTFVAGRNRSSVTL--YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISW 3272
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
E ++ G H + T+L I ++ + T C A N G +
Sbjct: 3273 YKE--EQLLSTGFKCKFLHDGQEY---TLLLIEAFPEDAAVYT--CEAKNDYGVATTSAS 3325
Query: 387 LT-----VTSDDDR----PPPIITNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEGE 436
L+ V S D PP IIT P T+ + A F C T + ++WY + +
Sbjct: 3326 LSVEVPEVVSPDQEMPVYPPAIIT--PLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDK 3382
Query: 437 ALIQNHRRNVTN-DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ + +T + T L + + D GTYT VAS+ G+ + L +++P
Sbjct: 3383 KIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAP 3436
Score = 68.1 bits (159), Expect = 2e-10
Identities = 83/320 (25%), Positives = 128/320 (40%), Gaps = 37/320 (11%)
Query: 292 PPSINLSPNSVN---VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
PPS+ L + V++G RF G P PT W+ +G+ + D+++
Sbjct: 18434 PPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSE------IKTDEHYTVE 18487
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-- 406
+ +VLTI + + D+ + + N AGS V LTV D P P GP N
Sbjct: 18488 TDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTVAVHLTVL---DVPGP--PTGPINIL 18541
Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYT 466
P + P+I + E + ++ V++ + + G
Sbjct: 18542 DVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC-E 18600
Query: 467 CVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
V R + G L +P F S P PP KP+ ++T+ + T+SW+
Sbjct: 18601 YVFRVRAENKIGVGPPLDSTPTVAKHKF-------SPPSPPGKPVVTDITENAATVSWTL 18653
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMF 585
G S I GY +E R ++G WV + + + + V L G TY F
Sbjct: 18654 PKSDGGSPITGYYME---RREVTGK--------WVRVNKTPIADLKFRVTGLYEGNTYEF 18702
Query: 586 IVRTENSHGLSGPSPVSDSV 605
V EN GLS PSP SD +
Sbjct: 18703 RVFAENLAGLSKPSPSSDPI 18722
Score = 68.1 bits (159), Expect = 2e-10
Identities = 156/706 (22%), Positives = 269/706 (38%), Gaps = 83/706 (11%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
+P +G P P V W K+ L + + L+I + + D G++ N AG +
Sbjct: 21725 VPIKGRPAPEVTWTKDNINLKNRANIE-NTESFTLLIIPECNRYDTGKFVMTIENPAGKK 21783
Query: 190 ESAIATLKIHIK-PYLITGPEDVVAQTGSSVTFQCRV----GGDPLPD-VLWRRSAGGGN 243
+ + P L P D+ T SVT + GG + + ++ +R A +
Sbjct: 21784 SGFVNVRVLDTPGPVLNLRPTDI---TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS 21840
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
K + ++ + E + AEN G + P+S+N
Sbjct: 21841 YSTATTKC-HKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLN 21899
Query: 304 VESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
+ ++ + T + A +P+ + G I D++ G+ + N T+
Sbjct: 21900 IM--DITKSTVSLAWPKPKHDGGSKITGY-VIEAQRKGSDQWTHITTVKGLECVVRNLTE 21956
Query: 363 KNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPIITNGPSNQTLPIKS--MAVFPC 419
+ T AVN AG S R + + + P + G + + K+
Sbjct: 21957 GEEY--TFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEI 22014
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKY 476
+ P+P + W + L Q R N T + +++ +SDSG Y A + G+
Sbjct: 22015 PVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGE- 22073
Query: 477 VWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSI 535
V I +H +PGPPT PI + V+ VT SW G I
Sbjct: 22074 -------VGDVITIQVH--------DIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPI 22118
Query: 536 LGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGL 595
Y VE+ R+T +S WV +A V +T Y L G+ Y F V+ +N +G+
Sbjct: 22119 SNYVVEM--RQT--------DSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGV 22168
Query: 596 SGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEI 655
GP S + +N ++ G + + + A DS TI +
Sbjct: 22169 -GPGITSACIV----ANYPFKVPGPPGTPQ-------------VTAVTKDSMTISWHEPL 22210
Query: 656 LN-FYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKF 714
+ + G + + + I + K ++ N F+ + L YEF +I
Sbjct: 22211 SDGGSPILGYHVERKERNGILWQTVSKALVPGNI---FKSSGLTDGIAYEFRVIAENMAG 22267
Query: 715 EGKPSN-SRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGI-ITGYNVVV 771
+ KPS S LD + P G P+ + + TV LKW+ PE G IT Y +V
Sbjct: 22268 KSKPSKPSEPMLALDPIDPPGKPVPLN---ITRHTVTLKWAKPE--YTGGFKITSY--IV 22320
Query: 772 NWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
D+P + + A + + + ++ LT +Y ++ A+ G
Sbjct: 22321 EKRDLPNGRWLKANFSNILE-NEFTVSGLTEDAAYEFRVIAKNAAG 22365
Score = 66.9 bits (156), Expect = 4e-10
Identities = 77/272 (28%), Positives = 113/272 (41%), Gaps = 32/272 (11%)
Query: 45 WYKGGVLV---VSDTHRSILPAG-GLFFLRATHGRVHSDAGVY-WCEATNSYGTARSRNA 99
WYK G+ + V + H+ ++ F+ T SDAG Y + N NA
Sbjct: 3179 WYKDGIEINFQVQERHKYVVERRIHRMFISETR---QSDAGEYTFVAGRNRSSVTLYVNA 3235
Query: 100 TLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
VL+E L+P + QS + C G P+P + W K Q LL G L
Sbjct: 3236 PEPPQVLQE---LQPVTVQSGKPARF---CAVISGRPQPKISWYKEEQ-LLSTGFKCKFL 3288
Query: 160 VDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-------------PYL 204
DG L++ +A DA Y C A+N G ++ A+L + + P +
Sbjct: 3289 HDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTS-ASLSVEVPEVVSPDQEMPVYPPAI 3347
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVI 263
IT +D V G FQCRV G L + + R+ +D L +
Sbjct: 3348 ITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAY 3407
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
DEG Y+ A N+VG VS++ L++ P SI
Sbjct: 3408 PEDEGTYTFVASNAVGQVSSTANLSLEAPESI 3439
Score = 66.5 bits (155), Expect = 5e-10
Identities = 83/325 (25%), Positives = 135/325 (41%), Gaps = 39/325 (12%)
Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
A D P PP P ++ T +SV+LSW + G S I+GY VEV + +N R
Sbjct: 20509 ARDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV---KRADSDNWVRC 20565
Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWE 616
+ + + + +T + V L+ Y F V N G S PS V D D L
Sbjct: 20566 N-----LPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKD---ILIP 20617
Query: 617 GTGVSNSTEYRNNILTDHIVELIEATPIDSK-TIKLMWEILNFYYLEGLFIYFRPLDNIT 675
G ++ + R ++ V + P+ + K+ W +P N+
Sbjct: 20618 PEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWS--------------KP--NVN 20660
Query: 676 IEYEMKTILHSNDVSGF-EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGP 734
+ + + S D F ++ KY ++ L + GK + V + LD GP
Sbjct: 20661 LRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILT--LENSCGKKEYTIVVKVLD--TPGP 20716
Query: 735 PINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATS 794
P+N+ + ++ + ++ W PP + + II N VV D A + + TT TS
Sbjct: 20717 PVNVTVKEISKDSAYVTWEPPIIDGGSPII---NYVVQKRD--AERKSWSTVTTECSKTS 20771
Query: 795 LIMTNLTSGVSYSVQIAAETIIGLG 819
+ NL G SY ++ AE G+G
Sbjct: 20772 FRVANLEEGKSYFFRVFAENEYGIG 20796
Score = 64.1 bits (149), Expect = 3e-09
Identities = 80/315 (25%), Positives = 132/315 (41%), Gaps = 36/315 (11%)
Query: 504 PGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
PGPPT P+ ++T+ SVTL W G S + Y + RET ++ W
Sbjct: 27497 PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYIL--LKRET--------STAVWTE 27546
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSN 622
++ V +T V L G Y F ++ EN G+S S VTV L T
Sbjct: 27547 VSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHID-SACVTV-----KLPYTTPGPP 27600
Query: 623 STEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKT 682
ST + N+ T + + P+ + ++ Y+LE + ++I + K
Sbjct: 27601 STPWVTNV-TRESITVGWHEPVSNGGSAVVG-----YHLE-----MKDRNSILWQKANKL 27649
Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFI 742
++ + + F++T++ YEF + GKPS+ D + PP N+ +
Sbjct: 27650 VIRT---THFKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACE-PPRNVRITD 27705
Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTS 802
++ +V L W P ITGY +V D+P + A T V + T I++ LT
Sbjct: 27706 ISKNSVSLSWQQPAFD-GGSKITGY--IVERRDLPDGRWTKASFTNVTE-TQFIISGLTQ 27761
Query: 803 GVSYSVQIAAETIIG 817
Y ++ A +G
Sbjct: 27762 NSQYEFRVFARNAVG 27776
Score = 64.1 bits (149), Expect = 3e-09
Identities = 41/123 (33%), Positives = 60/123 (48%), Gaps = 8/123 (6%)
Query: 487 PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546
P + F++AAD PGPP K + T +S+TL WS+ G S++ GY VE+ R+
Sbjct: 28077 PFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI--RQ 28134
Query: 547 TLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVT 606
T +++G V T YVV +L PG+ Y F V N G P +++ V
Sbjct: 28135 GEEEEWTTVSTKG------EVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQ 28188
Query: 607 VGD 609
D
Sbjct: 28189 AKD 28191
Score = 63.7 bits (148), Expect = 4e-09
Identities = 167/814 (20%), Positives = 292/814 (35%), Gaps = 92/814 (11%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
D V Q NC + A +W++ + + IL ++ LR +
Sbjct: 13575 DTRVKEQQEVVFNCEVNTEGAKA-KWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQ 13633
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRL-EP-ESKQSAQGDTVVLECLPPRGSPE 137
A Y TN G + + ++ V E+ R+ EP + ++ + +V C R +
Sbjct: 13634 AN-YNVSLTNHRG--ENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNV- 13689
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
+ W KNG+ + FD + + VD L I+D D G Y AG +S
Sbjct: 13690 -TLKWTKNGEEVPFD-NRVSYRVDKYKHMLTIKDCGFPDEGEYIV----TAGQDKSVAEL 13743
Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDD 254
L I + ED F C++ + +V W R+ G + G+ K D
Sbjct: 13744 LIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKA-NVKWYRN--GREIKEGKKYKFEKD 13800
Query: 255 GSLRLDNVILAD-EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
GS+ +I+ D + CE V + L V + P + P +E+
Sbjct: 13801 GSIH--RLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVF 13858
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
+ + + W N ++ G + + + + + I D+ + R
Sbjct: 13859 LAELNKDKVEVQWL--RNNMVVVQG-DKHQMMSEGKIHRLQICDIKPRDQGEYRFI---- 13911
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
A R KL + + P I + + + P+ W+
Sbjct: 13912 ----AKDKEARAKLELAA-----APKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFK 13962
Query: 434 EGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
E E L + + + K D G Y V ++HGK + IN
Sbjct: 13963 ENEPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGK--------AEGFIN---- 14010
Query: 494 FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553
+ DV PGP D V+L+W + G S I+GY VE R +
Sbjct: 14011 -LKVIDV---PGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVE---RRDIK---- 14059
Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPG-ITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612
+ WV+ R + V L G + Y+F V N G P + V ++
Sbjct: 14060 ---RKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPV----EAR 14112
Query: 613 SLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPL- 671
S ++ G N +TD ++ + L WE + + Y L
Sbjct: 14113 SKYDVPGPP-----LNVTITD----------VNRFGVSLTWEPPEYDGGAEITNYVIELR 14157
Query: 672 DNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSR-VAQTLDDV 730
D +I ++ + + D+S +T + + +Y F + + GKPS + + D +
Sbjct: 14158 DKTSIRWDTAMTVRAEDLSA-TVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPI 14216
Query: 731 P-DGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV 789
PP+N+ ++V LKW PP L+ I GY ++ + + + N +
Sbjct: 14217 ERPSPPVNLTSSDQTQSSVQLKWEPP-LKDGGSPILGY--IIERCE-EGKDNWIRCNMKL 14272
Query: 790 HQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
+ +T L G Y +++AE G+ S+
Sbjct: 14273 VPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSE 14306
Score = 63.3 bits (147), Expect = 5e-09
Identities = 61/205 (29%), Positives = 85/205 (41%), Gaps = 14/205 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
YV + E P ++++ VTV +PA G P P I WYK L+ + L G
Sbjct: 3232 YVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDG 3291
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-----EEFRLEPESKQS 119
+ L DA VY CEA N YG A + +A+L V V +E + P + +
Sbjct: 3292 QEYTLLLIEA-FPEDAAVYTCEAKNDYGVA-TTSASLSVEVPEVVSPDQEMPVYPPAIIT 3349
Query: 120 AQGDTVVLECLPPR-----GSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQT 173
DTV E P R + V W + + RM D L I +A
Sbjct: 3350 PLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPE 3409
Query: 174 DAGRYQCIARNAAGTRESAIATLKI 198
D G Y +A NA G + S+ A L +
Sbjct: 3410 DEGTYTFVASNAVG-QVSSTANLSL 3433
Score = 63.3 bits (147), Expect = 5e-09
Identities = 95/355 (26%), Positives = 144/355 (40%), Gaps = 45/355 (12%)
Query: 269 EYSCEAENSVGAVSASGYLTV-------YDPPSINLSP---NSVNVESGN-VARFTCTAT 317
E+ A+N+ GA+SA T Y+ P+I L P + + +++G+ + +
Sbjct: 21272 EFRIRAKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISIL 21331
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G+P P WS G I P D T+ ++LTI + D+ + +A N
Sbjct: 21332 GKPLPKSSWSKAGKD--IRPS---DITQITSTPTS-SMLTIKYATRKDAGEYTI-TATNP 21384
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
G+ K+TV D PP GP + I +++ T TP P+ ++
Sbjct: 21385 FGTKVEHVKVTVL-DVPGPP-----GP----VEISNVSAEKATLTWTP-PLEDGGSPIKS 21433
Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHF--F 495
I R T+V +D+ S + + +Y++ + + +
Sbjct: 21434 YILEKRETSRLLWTVVSEDIQ---SCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPV 21490
Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
+ D PGPP KP NVT + T+SW + G S I GY VE RE +
Sbjct: 21491 KMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVE--RRE--------K 21540
Query: 556 NSRGWV-VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
S WV I V V L G TY F V EN G+ PS SDSV + D
Sbjct: 21541 KSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKD 21595
Score = 62.9 bits (146), Expect = 7e-09
Identities = 112/466 (24%), Positives = 179/466 (38%), Gaps = 49/466 (10%)
Query: 17 QPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGR 75
+PL D+ V + A C + ++W+K G + I+ G + L +
Sbjct: 13305 RPLTDLQVREKEMARFECELSRE-NAKVKWFKDGAEIKKGKKYDIISKGAVRIL-VINKC 13362
Query: 76 VHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVLECLPPR 133
+ D Y CE TAR+ + VL EE F + + ++ DT+ L C +
Sbjct: 13363 LLDDEAEYSCEVR----TARTSGM---LTVLEEEAVFTKNLANIEVSETDTIKLVCEVSK 13415
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
P V W K + ++ G + L +G LVIQ+A DAG Y C R + +
Sbjct: 13416 --PGAEVIWYKGDEEIIETGRYEI-LTEGRKRILVIQNAHLEDAGNYNC--RLPSSRTDG 13470
Query: 192 AIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RV 249
+ K+H + I+ P+++ G F C + + P V W+R + G +
Sbjct: 13471 KV---KVHELAAEFISKPQNLEILEGEKAEFVCSISKESFP-VQWKRD--DKTLESGDKY 13524
Query: 250 KVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
V+ DG R + + L D G Y VGA A+ +LTV + I + V+
Sbjct: 13525 DVIADGKKRVLVVKDATLQDMGTYVV----MVGAARAAAHLTVIEKLRIVVPLKDTRVKE 13580
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
F C ++ N IF KY D V L I D +D
Sbjct: 13581 QQEVVFNCEVNTEGAKAKWFR---NEEAIF---DSSKY-IILQKDLVYTLRIRDAHLDDQ 13633
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
N V S N+ G + + ++D I+ +T+ KS+ F C +
Sbjct: 13634 ANYNV-SLTNHRGENVKSAANLIVEEEDL--RIVEPLKDIETMEKKSV-TFWC-KVNRLN 13688
Query: 427 PIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVA 469
+ W GE + ++R + D L +KD D G Y A
Sbjct: 13689 VTLKWTKNGEEVPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTA 13734
Score = 61.3 bits (142), Expect = 2e-08
Identities = 94/380 (24%), Positives = 141/380 (37%), Gaps = 43/380 (11%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
T +C+ G P P I WYK G + + ++ G LR + D G+Y A+
Sbjct: 1309 TFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVV-LPEDEGIYTAFAS 1367
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
N G A+ + +EP + A LE + S P + ++
Sbjct: 1368 NIKGN----------AICSGKLYVEPAAPLGAPTYIPTLEPVSRIRSLSP----RSVSRS 1413
Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
+ +RM + AR + R + T ES + L KP + P
Sbjct: 1414 PIRMSPARMSPARMSPARMSPARMSPGRRLE-------ETDESQLERL---YKPVFVLKP 1463
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDG--SLRLDNVILA 265
G + F +V G P+P+ W N +V + +DG SL + +
Sbjct: 1464 VSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPS 1523
Query: 266 DEGEYSCEAENSVGAVSASGYLTV-----YDPPSINLSPNSVNVESGNVARFTCTATGRP 320
D GE++ A+N G S S LTV P +VN++ G+ ATG P
Sbjct: 1524 DSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLEMKVRATGNP 1583
Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAV--FDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
P + W N II P KY + G L I+ T DS +A+N A
Sbjct: 1584 NPDIVWL--KNSDIIVP----HKYPKIRIEGTKGEAALKIDSTVSQDSA-WYTATAINKA 1636
Query: 379 GSSFVRGKLTVTSDDDRPPP 398
G R K+ V + P P
Sbjct: 1637 GRDTTRCKVNVEVEFAEPEP 1656
Score = 61.3 bits (142), Expect = 2e-08
Identities = 104/467 (22%), Positives = 180/467 (38%), Gaps = 50/467 (10%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
PY + D T L C + +P ++W+K G + + +++ A G +
Sbjct: 12945 PYFTGKLQDYTGVEKDEVILQCEISKADAP-VKWFKDGK-EIKPSKNAVIKADGKKRMLI 13002
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ SD G Y C+ + + + ++R +E ++A+ +T + E
Sbjct: 13003 LKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETARFETEISE--- 13059
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTR 189
+ + WK G+ LL D + +G +LV+ + R G + AA +
Sbjct: 13060 ----DDIHANWKLKGEALLQTPDCEIK-EEGKIHSLVLHNCRLDQTGG---VDFQAANVK 13111
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
SA +K + L+ +DV G + TF C + + +P V W G P +V
Sbjct: 13112 SSAHLRVKPRVIG-LLRPLKDVTVTAGETATFDCELSYEDIP-VEWYLK-GKKLEPSDKV 13168
Query: 250 KVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNVE 305
+G +L L +V L D GE A++ L V +PP P VE
Sbjct: 13169 VPRSEGKVHTLTLRDVKLEDAGEVQLTAKD----FKTHANLFVKEPPVEFTKPLEDQTVE 13224
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG-VTVLTINDTDKN 364
G A C + R + W G + KY A DG V L I+D
Sbjct: 13225 EGATAVLECEVS-RENAKVKWFKNGTEI-----LKSKKYEIVA--DGRVRKLVIHDCTPE 13276
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP-SNQTLPIKSMAVFPCTAIC 423
D + T C A ++ S L V PP + P ++ + K MA F C +
Sbjct: 13277 DIK-TYTCDAKDFKTSC----NLNVV-----PPHVEFLRPLTDLQVREKEMARFEC-ELS 13325
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK---SDSGTYTC 467
+ W+ +G + + + ++ + G + + ++K D Y+C
Sbjct: 13326 RENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEYSC 13372
Score = 60.1 bits (139), Expect = 5e-08
Identities = 97/403 (24%), Positives = 157/403 (38%), Gaps = 58/403 (14%)
Query: 425 PEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P P + W +G+ L + R + TLV+KD ++D G Y S+ G
Sbjct: 25662 PIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTK---- 25717
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQ 539
PI V PGPP P+ VT L+W+ + G ++I Y
Sbjct: 25718 ----SIPIT--------VKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 25765
Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
+E RET + W ++ V +Y V L+PG Y+F V N +G+ P
Sbjct: 25766 IE--KRET--------SRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPL 25815
Query: 600 PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659
S VT + ++ G ++ E + +T + + A P+D +
Sbjct: 25816 E-SGPVTACNP----YKPPGPPSTPEV--SAITKDSMVVTWARPVDDGGTE--------- 25859
Query: 660 YLEGLFIYFRPLDNIT-IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718
+EG + R + + + KT+ D+ +T L + YEF + G+P
Sbjct: 25860 -IEGYILEKRDKEGVRWTKCNKKTL---TDLR-LRVTGLTEGHSYEFRVAAENAAGVGEP 25914
Query: 719 SNSRVAQTLDDV--PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
S V D P GPP N ++ + ++V L WS P + + GY VV +
Sbjct: 25915 SEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKP-IYDGGAPVKGY--VVEVKEA 25971
Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
A++ T Q +T L Y+ +I A G+G
Sbjct: 25972 AADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 26014
Score = 60.1 bits (139), Expect = 5e-08
Identities = 106/451 (23%), Positives = 182/451 (40%), Gaps = 61/451 (13%)
Query: 177 RYQCIARNAAG-TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ----CRVGGDPLP 231
+++ A N+AG + S + + + P G D + T ++T + R GG +
Sbjct: 28755 QFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIV 28814
Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS----ASGYL 287
+ G + + + + D E+ A N+VG +S +SG +
Sbjct: 28815 GYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGII 28874
Query: 288 TVYD---PPSINLSP---NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
D PP + P + + ++SG R GRP P + W +G R
Sbjct: 28875 MTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI-----EKR 28929
Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
T V G T L + D + D R A N +GS+ K+ V D P ++
Sbjct: 28930 MNMEITDVL-GSTSLFVRDATR-DHRGVYTVEAKNASGSAKAEIKVKV---QDTPGKVV- 28983
Query: 402 NGPSNQT-LPIKSMAVF---PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
GP T + + M ++ P C P I Y +I+ +R + +++D
Sbjct: 28984 -GPIRFTNITGEKMTLWWDAPLNDGCAP---ITHY-----IIE--KRETSRLAWALIED- 29031
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALL----VDSPINPNIHFFRAADVSSLPGPPTKPITH 513
K ++ +YT + +Y + + + V P++ + A ++P P P
Sbjct: 29032 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVV--AQIQYTVPDAPGIPEPS 29088
Query: 514 NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-VIARR-VHQTH 571
N+T S+TL+W++ G S I Y +E RE + S WV VI++R + +T
Sbjct: 29089 NITGNSITLTWARPESDGGSEIQQYILE--RRE--------KKSTRWVKVISKRPISETR 29138
Query: 572 YVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
+ V L G Y F V EN+ G+ S +S
Sbjct: 29139 FKVTGLTEGNEYEFHVMAENAAGVGPASGIS 29169
Score = 59.7 bits (138), Expect = 6e-08
Identities = 93/402 (23%), Positives = 162/402 (40%), Gaps = 57/402 (14%)
Query: 425 PEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P I WY + + L N N T+ ++++KD D+ +SG Y + G S
Sbjct: 27827 PAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSA--SAT 27884
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540
+ V + PGPP PI VT +TL W G + I Y V
Sbjct: 27885 IRVQ--------------ILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIV 27930
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E RET + W +++ + + +I G Y+F VR N +G+ P
Sbjct: 27931 E--KRET--------SRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLE 27980
Query: 601 VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYY 660
SDSV V ++ G+ T+ N +T ++ + PI + + Y+
Sbjct: 27981 -SDSV-VAKNAFVTPGPPGIPEVTKITKNSMT-----VVWSRPIADGGSDI-----SGYF 28028
Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN 720
LE D ++ + K + + + ++T L + + Y++ + +G S
Sbjct: 28029 LE-------KRDKKSLGW-FKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSE 28080
Query: 721 -SRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778
S + D + P GPP I + +++ L WS P +TGY V + +
Sbjct: 28081 PSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYD-GGSAVTGYVVEIRQGE--- 28136
Query: 779 NKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIGLG 819
+ ++T + T +++NL GV+Y +++A G G
Sbjct: 28137 EEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQG 28178
Score = 59.3 bits (137), Expect = 8e-08
Identities = 100/398 (25%), Positives = 156/398 (39%), Gaps = 57/398 (14%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P I+W +GE L Q R NV T L +K+ +K D G YT A++ G + +
Sbjct: 25266 PRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLS 25325
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540
++V PGPP P+ + V+ V +SW G I Y V
Sbjct: 25326 VIV----------------LEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNYIV 25369
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E R+T + W +++ V +T + L G Y F + EN +G S +P
Sbjct: 25370 E--KRDTTTTT--------WHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS--AP 25417
Query: 601 VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDH-IVELIEATPIDSKTIKLMWEILNFY 659
+ + ++ G T + +I D +V+ E P++ K++ Y
Sbjct: 25418 LDSKAVIVQYP---FKEPGPPG-TPFVTSISKDQMLVQWHE--PVNDGGTKIIG-----Y 25466
Query: 660 YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719
+LE + ++I KT + F+ T L + +YEF + GKPS
Sbjct: 25467 HLEQ-----KEKNSILWVKLNKTPIQDTK---FKTTGLDEGLEYEFKVSAENIVGIGKPS 25518
Query: 720 NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPAN 779
D P PP E ++ V LKW P ITGY +V D+P
Sbjct: 25519 KVSECFVARD-PCDPPGRPEAIVITRNNVTLKWKKPAYD-GGSKITGY--IVEKKDLPDG 25574
Query: 780 KSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
+ M A T V + T ++ L Y ++ A G
Sbjct: 25575 RWMKASFTNVLE-TEFTVSGLVEDQRYEFRVIARNAAG 25611
Score = 58.4 bits (135), Expect = 1e-07
Identities = 91/356 (25%), Positives = 132/356 (37%), Gaps = 47/356 (13%)
Query: 6 VTSGEAPYIIE---QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL- 61
+T G+ P + P+D V + A C G+ + W K + S I
Sbjct: 9073 LTEGKNPPFFDIRLAPVDAVVG--ESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISY 9130
Query: 62 --PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLE-PES 116
+ L L+ G D+G Y C A N G S A L++ ++ F E+
Sbjct: 9131 LENSAHLTVLKVDKG----DSGQYTCYAVNEVGKD-SCTAQLNIKERLIPPSFTKRLSET 9185
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTD 174
+ +G++ LE GS V W KN + + + + LV+Q A D
Sbjct: 9186 VEETEGNSFKLEGRVA-GSQPITVAWYKNNIEIQPTSNCEITFKNN-TLVLQVRKAGMND 9243
Query: 175 AGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDP 229
AG Y C N AG SA+ T I IK P V G V C V G
Sbjct: 9244 AGLYTCKVSNDAG---SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSE 9300
Query: 230 LPDVLWRRSAGGGNMPLGRVKV-LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGY 286
+ W + AG P R G+ L L +V AD G+Y C+A N G+ +
Sbjct: 9301 PIRIQWLK-AGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSK 9359
Query: 287 LTVYDPPSIN---------------LSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
+T+ D P++ P S+ V A F G P P + W+
Sbjct: 9360 VTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 9415
Score = 58.4 bits (135), Expect = 1e-07
Identities = 109/456 (23%), Positives = 174/456 (38%), Gaps = 59/456 (12%)
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS--MAVFPCTAICTPEP 427
I +AVN + S +T+ +++ PP I + L +K+ T P P
Sbjct: 20194 IARTAVNISPPSEPSDPVTILAENV-PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMP 20252
Query: 428 IIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
++W +G L + N TL L +++ DSG YT A + G S + +
Sbjct: 20253 TVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSK--SATIKL 20310
Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
V PGPP + + LSW + G S I Y V+
Sbjct: 20311 K--------------VLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVD--K 20354
Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604
RET N W ++ V T V+ LI G Y F + EN +G+ P +
Sbjct: 20355 RETSRPN--------WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 20406
Query: 605 VTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGL 664
+ + + ++ G + +NI DH+ + P D + +L + +
Sbjct: 20407 I-----AKNPYDPPGRCDPPVI-SNITKDHMT-VSWKPPADDGGSPITGYLLEKRETQAV 20459
Query: 665 FIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRV 723
N T + K I+ + T L++ T+YEF + K GKPS+ S+
Sbjct: 20460 --------NWT-KVNRKPIIERT----LKATGLQEGTEYEFRVTAINKAGPGKPSDASKA 20506
Query: 724 AQTLD-DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM 782
A D P PP +++ ++V L W P + II GY V V D + +
Sbjct: 20507 AYARDPQYPPAPPAFPKVYDTTRSSVSLSWGKPAYDGGSPII-GYLVEVKRAD---SDNW 20562
Query: 783 VAINTTVH-QATSLIMTNLTSGVSYSVQIAAETIIG 817
V N + Q T +T L Y ++ A IG
Sbjct: 20563 VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG 20598
Score = 57.6 bits (133), Expect = 3e-07
Identities = 89/364 (24%), Positives = 144/364 (39%), Gaps = 37/364 (10%)
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARF 312
+++++ E E+ +A N+ G S + D PPSI+L + VE G
Sbjct: 17005 VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLK-EFMEVEEGTNVNI 17063
Query: 313 TCTATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
G P PT+ W + + D + V D L I + ++D+
Sbjct: 17064 VAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT-GLYT 17122
Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
+AVN G++ +L V RP P + GP + +S++ T P
Sbjct: 17123 ITAVNNLGTASKEMRLNVLG---RPGPPV--GP----IKFESVSADQMTLSWFPPKD--- 17170
Query: 432 YFEGEALIQNH--RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW----SGALLVD 485
+G + I N+ + N T V + + TYT +YV+ +
Sbjct: 17171 --DGGSKITNYVIEKREANRKTWVHVSSEPKEC-TYTIPKLLEGHEYVFRIMAQNKYGIG 17227
Query: 486 SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSR 545
P++ A ++ S+PG P KP +VT S+T++W + G S + GY +E+ +
Sbjct: 17228 EPLDSEPE--TARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--K 17283
Query: 546 ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
+T S R +R I Y V LI G Y F V N+ G+ S SD
Sbjct: 17284 DTTS-KRWKRVNRD--PIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA 17340
Query: 606 TVGD 609
T D
Sbjct: 17341 TARD 17344
Score = 57.6 bits (133), Expect = 3e-07
Identities = 36/101 (35%), Positives = 47/101 (46%), Gaps = 11/101 (10%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW-V 561
+PGPP KP+ +NVT ++L+W G S + G+ VE RNS W
Sbjct: 28683 IPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVE----------KKERNSILWQK 28732
Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
V + Y L+ G+ Y F V ENS GLS PS S
Sbjct: 28733 VNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 28773
Score = 57.2 bits (132), Expect = 3e-07
Identities = 90/342 (26%), Positives = 138/342 (40%), Gaps = 51/342 (14%)
Query: 273 EAENSVGAVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCTATGRPEPTMFWSVE 329
E S GA++A + DPP I++ P +++ V +G + G+P PT+ W ++
Sbjct: 23451 EPSESTGAITARDEV---DPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQW-IK 23506
Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
G++ + +R + +T D T L++ D + DS N I+ A N AG V + V
Sbjct: 23507 GDQEL--SNTARLEIKST---DFATSLSVKDAVRVDSGNYIL-KAKNVAGERSVTVNVKV 23560
Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP------EPIIAWYFEGEALIQNHR 443
DRP GP + I + CT P II + E +
Sbjct: 23561 L---DRP------GPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVW 23611
Query: 444 RNV-TNDGTLVLK--DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADV 500
V N TL K L + + T+ +A +++G G L P+ F
Sbjct: 23612 TVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGV----GEPLESEPVVAKNPFV----- 23662
Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
+P P P VT S+ + W + G S ILGY +E +E + +
Sbjct: 23663 --VPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHK----- 23715
Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
R + + V LI Y F V EN+ GLS PSP S
Sbjct: 23716 ----RLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPS 23753
Score = 57.2 bits (132), Expect = 3e-07
Identities = 75/320 (23%), Positives = 126/320 (39%), Gaps = 33/320 (10%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P + + +S +V+ G + +GRP+PT+ W+ +G P + + T D
Sbjct: 24157 PDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG-----LPLKQTTRINVTDSLD- 24210
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--PIITNGPSNQTLP 410
+T L+I +T K+D + A N G ++ VT D PP P+ + S +++
Sbjct: 24211 LTTLSIKETHKDDGGQYGITVA-NVVGQKTASIEI-VTLDKPDPPKGPVKFDDVSAESIT 24268
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
+ T C I + + + TL + L + A
Sbjct: 24269 LSWNPPL-YTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAE 24327
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+R+G+ S AL D PI + PGPP P ++ S+ + W +
Sbjct: 24328 NRYGQ---SFALESD-PIVAQYPYKE-------PGPPGTPFATAISKDSMVIQWHEPVNN 24376
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRT 589
G S ++GY +E RNS W + + +H T + ++L GI Y F V
Sbjct: 24377 GGSPVIGYHLE----------RKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYA 24426
Query: 590 ENSHGLSGPSPVSDSVTVGD 609
EN G+ S S+ D
Sbjct: 24427 ENIVGVGKASKNSECYVARD 24446
Score = 56.8 bits (131), Expect = 4e-07
Identities = 94/378 (24%), Positives = 138/378 (36%), Gaps = 24/378 (6%)
Query: 178 YQCIARNAAG-----TRESAIATLKIHIK-PYLITGPE--DV-VAQTGSSVTFQCRVGGD 228
++ IARNAAG + S T + I P P+ DV V G + + + G
Sbjct: 25602 FRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGK 25661
Query: 229 PLPDVLWRRSAGGGNMPLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285
P+PDV+W + R+++ + +L + + I D G+Y + N G S
Sbjct: 25662 PIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPI 25721
Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
+ V D P P V V C P P + II +
Sbjct: 25722 TVKVLDRPGPPEGPLKVT----GVTAEKCYLAWNP-PLQDGGANISHYII-EKRETSRLS 25775
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
T V V L T I AVN G VT+ + PP + P
Sbjct: 25776 WTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 25835
Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGT 464
+ SM V + I Y + + R N TL DL +G
Sbjct: 25836 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT--DLRLRVTGL 25893
Query: 465 YTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
S + A V P P++ F+RA D PGPP+ P + + +SV+L+W
Sbjct: 25894 TE--GHSYEFRVAAENAAGVGEPSEPSV-FYRACDALYPPGPPSNPKVTDTSRSSVSLAW 25950
Query: 525 SQNNKIGSSSILGYQVEV 542
S+ G + + GY VEV
Sbjct: 25951 SKPIYDGGAPVKGYVVEV 25968
Score = 56.4 bits (130), Expect = 6e-07
Identities = 87/353 (24%), Positives = 141/353 (39%), Gaps = 41/353 (11%)
Query: 269 EYSCEAENSVGAVS----ASGYLTVYD---PPSINLSP---NSVNVESGNVARFTCTATG 318
E+ A N+ +VS ++G + V D PP + + + + V++G V + G
Sbjct: 26683 EFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAG 26742
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
RP P + W+ +G I +R + +T D T+LT+ D + D+ V + N A
Sbjct: 26743 RPLPVISWAKDG---IEIEERARTEIIST---DNHTLLTVKDCIRRDT-GQYVLTLKNVA 26795
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
G+ V V D+P GP L I + C+ + P + +
Sbjct: 26796 GTRSVAVNCKVL---DKP------GPPAGPLEINGLTAEKCS-LSWGRPQEDGGADIDYY 26845
Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH-GKYVWSGALLVDSPINPNIHFFRA 497
I R T+ +L + + + + + V P+ +A
Sbjct: 26846 IVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVA--IKA 26903
Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNS 557
D ++P PPT +VT S+TL WS+ G S I GY +E RE +NS
Sbjct: 26904 LDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE--RRE--------KNS 26953
Query: 558 RGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
WV + ++ V+ L G Y + V EN+ GLS PS S + D
Sbjct: 26954 LRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAED 27006
Score = 56.0 bits (129), Expect = 8e-07
Identities = 120/556 (21%), Positives = 206/556 (37%), Gaps = 70/556 (12%)
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRH 473
FP P P W +G + + V D L +K+ + D+G Y S+
Sbjct: 18457 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAA 18516
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGS 532
G + +H V +PGPPT PI +VT +T+SW G
Sbjct: 18517 GSKTVA------------VHL----TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGG 18560
Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
S ++ Y VE +T +++ W V++ +T + L G Y+F VR EN
Sbjct: 18561 SPVINYIVEK--------QDTRKDT--WGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENK 18610
Query: 593 HGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLM 652
G+ GP P+ + TV S G T+ N T +
Sbjct: 18611 IGV-GP-PLDSTPTVAKHKFSPPSPPGKPVVTDITENAAT------------------VS 18650
Query: 653 WEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEF--FLIPF 710
W + + Y+ +T ++ D+ F +T L + YEF F
Sbjct: 18651 WTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLK-FRVTGLYEGNTYEFRVFAENL 18709
Query: 711 YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVV 770
+ PS+ + P GPPIN ++ + T L W+ P L I GY VV
Sbjct: 18710 AGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKP-LSDGGSPILGY-VV 18767
Query: 771 VNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
A + + + + Q + + L G Y +I A I+G G + +
Sbjct: 18768 ECQKPGTAQWNRINKDELIRQC-AFRVPGLIEGNEYRFRIKAANIVGEGEPRE-----LA 18821
Query: 831 SRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAK 890
+ D+L +P E+ + D V+ I + K I + ++ + +
Sbjct: 18822 ESVIAKDIL--HPPEVELDVTCRD-VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVR 18878
Query: 891 KSALPNIYDSNGTSLVTQMNIKAAVSLSHP--LTSCYNKNTVTKTESLLWMENQPGVCLS 948
+ + I D ++ IK AV H + S N + + +++ + ++PG C +
Sbjct: 18879 EKRVDLIQDLPR----VELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQN 18934
Query: 949 GNQTSQSKEKTNFEYD 964
T+ +KE ++
Sbjct: 18935 LKVTNVTKENCTISWE 18950
Score = 55.2 bits (127), Expect = 1e-06
Identities = 51/186 (27%), Positives = 81/186 (43%), Gaps = 27/186 (14%)
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P + W + GE+L + + ++ L++ ++++ DSG Y + G S +
Sbjct: 22815 PAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSG----SKSAF 22870
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
V+ R D PGPP VT TSVTL+W G S I Y VE
Sbjct: 22871 VN---------VRVLDT---PGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVE-- 22916
Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
RE+ + + +A H+T + V L G +Y F V EN +G+ P+ ++
Sbjct: 22917 KRES--------TRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAE 22968
Query: 604 SVTVGD 609
SV +
Sbjct: 22969 SVKASE 22974
Score = 55.2 bits (127), Expect = 1e-06
Identities = 76/307 (24%), Positives = 117/307 (38%), Gaps = 36/307 (11%)
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
V +G AR GRP P + WS E G DK + T L+I++ D+
Sbjct: 24963 VRAGGSARIHIPFKGRPTPEITWSRE-------EGEFTDKVQIEKGVN-YTQLSIDNCDR 25014
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
ND+ I+ N +GS +TV D PP Q L +K + +
Sbjct: 25015 NDAGKYIL-KLENSSGSK--SAFVTVKVLDTPGPP--------QNLAVKEVRKDSAFLVW 25063
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P PII +G A ++N+ + ++ S T V + G + +
Sbjct: 25064 EP-PII----DGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMA 25118
Query: 484 VDS-PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
+ + + A + P PP K +V+ TS +L W + G S +LGY VE+
Sbjct: 25119 ENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 25178
Query: 543 FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
P+ + W ++A + VV L G Y F V+ N G S P +
Sbjct: 25179 ----------QPKGTEKWSIVAES-KVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLG 25227
Query: 603 DSVTVGD 609
V D
Sbjct: 25228 VPVIAKD 25234
Score = 54.8 bits (126), Expect = 2e-06
Identities = 107/394 (27%), Positives = 160/394 (40%), Gaps = 60/394 (15%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYT-CVASSRHGKYVWSG 480
P+ + W +G+ L + R NV++ T L +K+ K D GTY CV++S +G
Sbjct: 26349 PQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNS-------AG 26401
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
++ V PI V PGPP V+ S+T+SW+ G I Y V
Sbjct: 26402 SITV--PIT--------IIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIV 26451
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E +ET S W ++++ V +T + L G Y F V EN +G S S
Sbjct: 26452 E--KKET--------TSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSE 26501
Query: 601 VSDSVTVGDDSNSLWEGT-GVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659
S V S GT V ++T ++ +L V + + S+ I E
Sbjct: 26502 SSAVVAEYPFSPPGPPGTPKVVHAT--KSTMLVTWQVPVNDG---GSRVIGYHLE----- 26551
Query: 660 YLEGLFIYFRPLDNITI-EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKP 718
Y E I + + I I + +MK VSG + + +Y Y + GK
Sbjct: 26552 YKERSSILWSKANKILIADTQMK-------VSGLDEGLMYEYRVYAENIAGI-----GKC 26599
Query: 719 SNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778
S S D P PP E+ + +V LKWS P ITGY +V ++P
Sbjct: 26600 SKSCEPVPARD-PCDPPGQPEVTNITRKSVSLKWSKPHYD-GGAKITGY--IVERRELPD 26655
Query: 779 NKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
+ + N T Q T +T LT Y ++ A
Sbjct: 26656 GR-WLKCNYTNIQETYFEVTELTEDQRYEFRVFA 26688
Score = 54.8 bits (126), Expect = 2e-06
Identities = 97/440 (22%), Positives = 164/440 (37%), Gaps = 58/440 (13%)
Query: 389 VTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRN 445
+ + D+ PPI+ GP L IKS A+ P P + W+ +G + +
Sbjct: 28874 IMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNME 28933
Query: 446 VTN---DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502
+T+ +L ++D + G YT A + SG+ + + V
Sbjct: 28934 ITDVLGSTSLFVRDATRDHRGVYTVEAKNA------SGSAKAEIKVK----------VQD 28977
Query: 503 LPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
PG PI N+T +TL W G + I Y +E RET + W
Sbjct: 28978 TPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIE--KRET--------SRLAWA 29027
Query: 562 VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS 621
+I + Y LI G Y F V N G+ P+ V ++ + G+
Sbjct: 29028 LIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG--RPLDSDPVVAQIQYTVPDAPGIP 29085
Query: 622 NSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMK 681
+ +T + + L A P ++ IL + + +
Sbjct: 29086 EPSN-----ITGNSITLTWARPESDGGSEIQQYILE------------RREKKSTRWVKV 29128
Query: 682 TILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDV-PDGPPINIE 739
+ F++T L + +YEF ++ G S SR+ + + V P GPP ++
Sbjct: 29129 ISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVK 29188
Query: 740 MFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTN 799
+ + TTV L+WS P II GY + + D+ +N T +T+
Sbjct: 29189 VTDTSKTTVSLEWSKPVFDGGMEII-GYIIEMCKADL---GDWHKVNAEACVKTRYTVTD 29244
Query: 800 LTSGVSYSVQIAAETIIGLG 819
L +G Y +++A G G
Sbjct: 29245 LQAGEEYKFRVSAINGAGKG 29264
Score = 54.4 bits (125), Expect = 2e-06
Identities = 49/189 (25%), Positives = 70/189 (37%), Gaps = 13/189 (6%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-FD 351
P L P S G ARF GRP P FW +G + + D H + D
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIV------NDYTHKVVIKED 1510
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
G L I +DS V A N AG S + LTV + + + P+ N +
Sbjct: 1511 GTQSLIIVPATPSDSGEWTVV-AQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKE 1569
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYT 466
S A P P I W + ++ + + +GT L + DS YT
Sbjct: 1570 GSQLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYT 1629
Query: 467 CVASSRHGK 475
A ++ G+
Sbjct: 1630 ATAINKAGR 1638
Score = 54.0 bits (124), Expect = 3e-06
Identities = 63/270 (23%), Positives = 99/270 (36%), Gaps = 16/270 (5%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
D SL+ E E +V A G D P I+ E G++ T
Sbjct: 4250 DESLKPSEEKEESSSESGTEEVATVKIQEAEGGFIKEDGPMIHTPLVDTVSEEGDIVHLT 4309
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
+ T E W E + P S +K+ + T L I+ + D + VC
Sbjct: 4310 TSITNAKEVN--WYFENK---LVP--SDEKFKCLQDQNTYT-LVIDKVNTEDHQGEYVCE 4361
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
A+N +G + KLTV R P+I + + +A F C P W+
Sbjct: 4362 ALNDSGKTATSAKLTVVK---RAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFK 4418
Query: 434 EGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
G + ++ + ++ + +L + D G YTC AS+ +G + L V P
Sbjct: 4419 AGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 4478
Query: 491 NIHFFRAADVSSLPGPPTKPITHNVTDTSV 520
R +++ G K I VT T V
Sbjct: 4479 TF-LSRPKSLTTFVGKAAKFIC-TVTGTPV 4506
Score = 54.0 bits (124), Expect = 3e-06
Identities = 54/222 (24%), Positives = 85/222 (38%), Gaps = 29/222 (13%)
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRNV 446
+ + + P + +TL +K+ A F T P P + W L +
Sbjct: 27103 IAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDT 27162
Query: 447 TNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPG 505
T+ T L +++ +++DSG YT + V S A L V PG
Sbjct: 27163 TDSRTSLTIENANRNDSGKYTLTIQN-----VLSAASLT-----------LVVKVLDTPG 27206
Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
PPT +VT S LSW G + + Y +E RE + + WV +
Sbjct: 27207 PPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIE--KREA--------SKKAWVSVTN 27256
Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
++ Y V +L G Y F V EN G+ P+ + V +
Sbjct: 27257 NCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETKEGVKI 27298
Score = 53.2 bits (122), Expect = 5e-06
Identities = 35/118 (29%), Positives = 49/118 (41%), Gaps = 5/118 (4%)
Query: 177 RYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
R++ + A E+A + I P L++G ++V G SVT +C + G P P V
Sbjct: 915 RFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTV 974
Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
W R + G RL D G ++C A N G VS S YL V
Sbjct: 975 TWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032
Score = 53.2 bits (122), Expect = 5e-06
Identities = 35/102 (34%), Positives = 47/102 (46%), Gaps = 10/102 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P PP KP +V TSV L+W++ G + I Y +E+ T WV +
Sbjct: 14911 PWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDE----------WVRV 14960
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
A V T +++ L+ G Y F VR N G S PS SD V
Sbjct: 14961 AEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPV 15002
Score = 52.8 bits (121), Expect = 7e-06
Identities = 101/478 (21%), Positives = 180/478 (37%), Gaps = 46/478 (9%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
+ + +P + V AT + GG P P ++W KG ++ R + G
Sbjct: 9382 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEI 9441
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
+D+G+Y C A N +G S N L V +++ ++E + + + T +L+
Sbjct: 9442 RDTTKTDSGLYRCVAFNEHGEIES-NVNLQVDERKKQEKIEGDLRAMLK-KTPILKKGAG 9499
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLV-----IQDARQTDAGRYQCIARNAA 186
+ KN ++ +RM+ + D L+ ++ +++ + R + +
Sbjct: 9500 EEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERS 9559
Query: 187 GTRESAIATLKIHIKPYL-----ITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRS 238
E L I+ L +T +D+ QT + F+ + + P++
Sbjct: 9560 ERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKIN-YPEIKLSWY 9618
Query: 239 AGGGNM-PLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
G + P + ++ DG +LR+ N L D+G Y G AS LTV +P +
Sbjct: 9619 KGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC----GPHIASAKLTVIEP-A 9673
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
V ++ G TC + P W G I R H T V V
Sbjct: 9674 WERHLQDVTLKEGQTCTMTCQFSV-PNVKSEWFRNGR---ILKPQGR---HKTEVEHKVH 9726
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
LTI D D + C + S+ +R + P T N +
Sbjct: 9727 KLTIADVRAED-QGQYTCKYEDLETSAELR--------IEAEPIQFTKRIQNIVVSEHQS 9777
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVA 469
A F C + + I+ WY L ++ + N NDG + + ++ D G Y+ +A
Sbjct: 9778 ATFECE-VSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVIA 9834
Score = 52.8 bits (121), Expect = 7e-06
Identities = 44/129 (34%), Positives = 55/129 (42%), Gaps = 14/129 (10%)
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE-- 541
+ P P+ F A D + P PP P + T SV L+W G S ILGY VE
Sbjct: 18021 IGDPSPPSKPVF-AKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQ 18079
Query: 542 -VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
V E N+TP + +T Y V L G TY F V N+ G S P+
Sbjct: 18080 KVGDEEWRRANHTPES----------CPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAH 18129
Query: 601 VSDSVTVGD 609
V + V V D
Sbjct: 18130 VPEPVLVKD 18138
Score = 52.8 bits (121), Expect = 7e-06
Identities = 70/320 (21%), Positives = 117/320 (36%), Gaps = 33/320 (10%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
PS+ L N+ ++++G + GRP P + W +G +R TA
Sbjct: 25239 PSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEP---LKQTTRVNVEETATS-- 25293
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
TVL I + +K+D V +A N AG++ + V P + + +
Sbjct: 25294 -TVLHIKEGNKDDFGKYTV-TATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVI 25351
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
S T C I + + T+ + L + A +R
Sbjct: 25352 SWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENR 25411
Query: 473 HGKY--VWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+GK + S A++V P PGPP P +++ + + W +
Sbjct: 25412 YGKSAPLDSKAVIVQYPFKE-------------PGPPGTPFVTSISKDQMLVQWHEPVND 25458
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRT 589
G + I+GY +E +NS WV + + + T + L G+ Y F V
Sbjct: 25459 GGTKIIGYHLE----------QKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSA 25508
Query: 590 ENSHGLSGPSPVSDSVTVGD 609
EN G+ PS VS+ D
Sbjct: 25509 ENIVGIGKPSKVSECFVARD 25528
Score = 52.4 bits (120), Expect = 9e-06
Identities = 36/129 (27%), Positives = 57/129 (44%), Gaps = 7/129 (5%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDD-GSLRLDNVIL 264
+ VV GS+ TF+ + G P+P+V W R +P ++ D L + V
Sbjct: 13 QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV---YDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
A+ G YS +A N G +++ L V PP+ S+ V G+ R TG P
Sbjct: 73 ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPT 132
Query: 322 PTMFWSVEG 330
P + + +G
Sbjct: 133 PVVKFYRDG 141
Score = 52.4 bits (120), Expect = 9e-06
Identities = 34/108 (31%), Positives = 50/108 (46%), Gaps = 10/108 (9%)
Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
RA D LP PP+KP + T++T++W + G + I GY VE + + +
Sbjct: 27003 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ 27062
Query: 556 NSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+ RG T Y + L G Y+F V++ N G S PS SD
Sbjct: 27063 SLRG----------TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 27100
Score = 52.0 bits (119), Expect = 1e-05
Identities = 51/198 (25%), Positives = 77/198 (38%), Gaps = 10/198 (5%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRMHLVDG-GNLVIQDARQTDAGR 177
+G T E G P P V W ++GQ + ++ DG L I + ++GR
Sbjct: 19 EGSTATFEA-HISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGR 77
Query: 178 YQCIARNAAGTRESAIATL-KIHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
Y A N +G S L K P + + + + GS V Q RV G P P V +
Sbjct: 78 YSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKF 137
Query: 236 RRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
R L ++ +G SL + D G YS A NSVG +++ L V
Sbjct: 138 YRDGAEIQSSLD-FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQGE 196
Query: 293 PSINLSPNSVNVESGNVA 310
+ V + ++
Sbjct: 197 EEVPAKKTKTIVSTAQIS 214
Score = 52.0 bits (119), Expect = 1e-05
Identities = 103/442 (23%), Positives = 168/442 (38%), Gaps = 42/442 (9%)
Query: 38 SPSPAIR-WYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
SPS AI W K G + + G L ++ SDAG Y C ++
Sbjct: 12070 SPSTAITTWMKDGSNIRESPKHRFIADGKDRKLHIIDVQL-SDAGEYTC-VLRLGNKEKT 12127
Query: 97 RNATLHVAVLREEF-RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
A L V L F + E +G + L C + E +V W+K+G+ ++
Sbjct: 12128 STAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSC---ELNKERDVVWRKDGKIVVEKPGR 12184
Query: 156 RMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
+ V G L I DA TDAG Y NA S+ + I+ +L+ D
Sbjct: 12185 IVPGVIGLMRALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHV 12244
Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS---LRLDNVILADEGE 269
+ + F C + D P++ W + P + ++L DG+ L++ N + D E
Sbjct: 12245 KPKGTAIFACDIAKD-TPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAE 12303
Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSP-NSVNVESGNVARFTCTATGRPEPTMFWSV 328
Y+ E E LT+ + L P V + A F + P W +
Sbjct: 12304 YAVEIEGK----RYPAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQ-WKL 12358
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
+G ++ P + + G LT+ K D ++ A+N + LT
Sbjct: 12359 KGE--LLRPSPTCE----IKAEGGKRFLTLRKV-KLDQAGEVLYQALN----AITTAILT 12407
Query: 389 VTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
V + D P+ + T+P + A F C + T E + W + + + + ++
Sbjct: 12408 VKEIELDFAVPL-----KDVTVPERRQARFEC--VLTREANVIWSKGPDIIKSSDKFDII 12460
Query: 448 NDG---TLVLKDLDKSDSGTYT 466
DG LV+ D D G YT
Sbjct: 12461 ADGKKHILVINDSQFDDEGVYT 12482
Score = 52.0 bits (119), Expect = 1e-05
Identities = 83/351 (23%), Positives = 137/351 (39%), Gaps = 51/351 (14%)
Query: 269 EYSCEAENSVGAVSA----SGYLTVYDP---PSINLS---PNSVNVESGNVARFTCTATG 318
E+ A+N+ GA+S S +T D P I + ++V +++G R +G
Sbjct: 22355 EFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSG 22414
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
RP PTM WS +G G ++ + + D T L D+ + DS +A N
Sbjct: 22415 RPPPTMEWSKDGKE---LEGTAKLEIK---IADFSTNLVNKDSTRRDS-GAYTLTATNPG 22467
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY---FEG 435
G F + V D PP GP +AV T + + + +++W+ +G
Sbjct: 22468 G--FAKHIFNVKVLDRPGPP---EGP---------LAV---TEVTSEKCVLSWFPPLDDG 22510
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG-KYVWSGALLVDSPINPNIHF 494
A I ++ L ++ T V G +Y++ + + +
Sbjct: 22511 GAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLES 22570
Query: 495 FRAADVSSL--PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNN 552
V+ P PP P +T S+ + W + G S I+ Y VE R +G
Sbjct: 22571 EPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVE---RRDKAGQR 22627
Query: 553 TPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
W+ ++ + Y V L G Y F + EN+ G+S PSP S
Sbjct: 22628 -------WIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTS 22671
Score = 52.0 bits (119), Expect = 1e-05
Identities = 49/176 (27%), Positives = 74/176 (42%), Gaps = 30/176 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P + W+ + L Q R N N+ L +KD + D G Y ++ G+ + +
Sbjct: 23102 PTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLN 23161
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540
++V PGPPT P+ + VT S+TLSW G SSI Y V
Sbjct: 23162 VIV----------------LDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIV 23205
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
E R+T ++ W +++ V +T L G Y F + EN +G S
Sbjct: 23206 E--KRDT--------STTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 23251
Score = 51.6 bits (118), Expect = 2e-05
Identities = 34/110 (30%), Positives = 45/110 (40%), Gaps = 9/110 (8%)
Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
V PGPP + ++ TSV W G S I+ Y TL + +
Sbjct: 15725 VLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINY--------TLEKKDKTKPDSE 15776
Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
W+V+ + Y V LI G Y+F VR EN G GP VS + D
Sbjct: 15777 WIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG-PGPPCVSKPLVAKD 15825
Score = 51.2 bits (117), Expect = 2e-05
Identities = 30/99 (30%), Positives = 47/99 (47%), Gaps = 3/99 (3%)
Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG 450
S+ + PI SN + + +A T I P+P I W+F G L + DG
Sbjct: 3496 SEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFDG 3555
Query: 451 ---TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
+L++ D G YTC+AS+ +GK + S L ++S
Sbjct: 3556 DDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKINS 3594
Score = 50.8 bits (116), Expect = 3e-05
Identities = 74/318 (23%), Positives = 120/318 (37%), Gaps = 36/318 (11%)
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ V++G T TG+PEP + W+ +I + +DK + +TI D+
Sbjct: 14627 LTVKAGTKIELPATVTGKPEPKITWT---KADMI---LKQDKRITIENVPKKSTVTIVDS 14680
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
++D+ T + AVN G + ++ V P +N++ + +
Sbjct: 14681 KRSDT-GTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESC----LLTWNPPR 14735
Query: 422 ICTPEPIIAWYFEGEALIQN--HRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
I + E A H+ + T D L + + A + +G
Sbjct: 14736 DDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGV--- 14792
Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGY 538
G + SPI F PGPPT+ ++T +VTL+W + + G S I GY
Sbjct: 14793 -GEPVQASPITAKYQF-------DPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 14844
Query: 539 QVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSG 597
VE +T WV + V T Y VK L Y F V EN G
Sbjct: 14845 WVERLDPDT----------DKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGK 14894
Query: 598 PSPVSDSVTVGDDSNSLW 615
PS ++ + + D + W
Sbjct: 14895 PSKSTEPILIKDPIDPPW 14912
Score = 50.8 bits (116), Expect = 3e-05
Identities = 97/407 (23%), Positives = 161/407 (39%), Gaps = 63/407 (15%)
Query: 425 PEPIIAWYFEGEALIQNH--RRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P+P I+W +G L ++ R + T N TL +K+ K G YT + + +
Sbjct: 28518 PKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPIT 28577
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQV 540
++ P P P PI + + SV LSW G I Y +
Sbjct: 28578 VITLGP----------------PSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSI 28621
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E RET N W ++ V +T + V +L+ Y F VR EN +G+S P
Sbjct: 28622 E--KRETSQTN--------WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVS--QP 28669
Query: 601 VSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYY 660
+ S+ V + G Y N+ +D + +A D + E+ F+
Sbjct: 28670 LVSSIIVAKHQFRIPGPPG--KPVIY--NVTSDGMSLTWDAPVYDGGS-----EVTGFHV 28720
Query: 661 LEGLFIYFRPLDNITIEYEMKTILHSNDVSG--FEITSLRKYTKYEFFLIPFYKKFEGKP 718
+ +I ++ ++++ +SG + T L + Y+F + + + G
Sbjct: 28721 --------EKKERNSILWQK---VNTSPISGREYRATGLVEGLDYQFRV--YAENSAGLS 28767
Query: 719 SNSRVAQ-TLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
S S ++ TL P PP + + T+ LKW+PP L+ I GY++
Sbjct: 28768 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPP-LRDGGSKIVGYSIEKR----Q 28822
Query: 778 ANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG-LGPFSQ 823
N+ V N T +T L+ G Y +I A +G + P SQ
Sbjct: 28823 GNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQ 28869
Score = 50.0 bits (114), Expect = 5e-05
Identities = 38/109 (34%), Positives = 47/109 (43%), Gaps = 11/109 (10%)
Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
S P PP K +VT SV+LSW + G S ILGY VE+ + S W
Sbjct: 22973 SERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM----------QTKGSDKW 23022
Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
A V T + LI G Y F V +N G+S P +S V D
Sbjct: 23023 ATCA-TVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKD 23070
Score = 50.0 bits (114), Expect = 5e-05
Identities = 80/346 (23%), Positives = 137/346 (39%), Gaps = 41/346 (11%)
Query: 269 EYSCEAENSVGAVS----ASGYLTVYDP---PSINLSP---NSVNVESGNVARFTCTATG 318
E+ A+N+ GA+S ++G +T D P I++ P +++ V +G R G
Sbjct: 24519 EFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHG 24578
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
+P PT+ W + G++ I +R + T D +L + D + D I+ A N A
Sbjct: 24579 KPLPTIEW-LRGDKEI--EESARCEIKNT---DFKALLIVKDAIRIDGGQYIL-RASNVA 24631
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
GS + V DRP GP + + + C+ +P P+ +
Sbjct: 24632 GSKSFPVNVKVL---DRP------GPPEGPVQVTGVTSEKCSLTWSP-PLQDGGSDISHY 24681
Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS-GALLVDSPINPNIHFFRA 497
+ R T+V ++ + + + + + + V P+ +
Sbjct: 24682 VVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKN 24741
Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNS 557
V LPGPP N+ S+T+ W++ + G S I+GY VE R+
Sbjct: 24742 PFV--LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVE----------KRDRSG 24789
Query: 558 RGWVVI-ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
W+ RR+ V L Y F V EN+ G+ PSP +
Sbjct: 24790 IRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPAT 24835
Score = 49.6 bits (113), Expect = 7e-05
Identities = 35/117 (29%), Positives = 48/117 (41%), Gaps = 11/117 (9%)
Query: 494 FFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553
F + AD P PP + + T +SV L W K G S ILGY +E
Sbjct: 14209 FVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIE----------RC 14258
Query: 554 PRNSRGWV-VIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
W+ + V + Y V L G Y++ V EN G+S PS + +T D
Sbjct: 14259 EEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADD 14315
Score = 49.6 bits (113), Expect = 7e-05
Identities = 59/242 (24%), Positives = 89/242 (36%), Gaps = 23/242 (9%)
Query: 374 AVNYAGSSF---VRGKLTVTSDDDRPPPIITNGPSNQTL-PIKSMAVFPCTAICTPEPII 429
AVN AG S G++ T + P I G + + S P P P
Sbjct: 16710 AVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKS 16769
Query: 430 AWYFEGEA--LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+W F+G+A +++ ++ D L + + S S GKY ++ +
Sbjct: 16770 SWEFDGKAKKAMKDGVHDIPEDAQL--ETAENSSVIIIPECKRSHTGKY----SITAKNK 16823
Query: 488 INPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRET 547
R V +PGPP ++T S LSW + G I GY +E + T
Sbjct: 16824 AGQKTANCRVK-VMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIE---KRT 16879
Query: 548 LSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
+ G + W + T +VV L+ Y F VR EN G+ P T
Sbjct: 16880 IDG-------KAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTA 16932
Query: 608 GD 609
D
Sbjct: 16933 RD 16934
Score = 49.6 bits (113), Expect = 7e-05
Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 11/108 (10%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+PGPP P+ + S+ + W++ G S ++GY +E RNS WV
Sbjct: 23267 VPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLE----------RKERNSILWVK 23316
Query: 563 IARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+ + + QT + L G+ Y F V EN G+ PS VS+ D
Sbjct: 23317 LNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD 23364
Score = 49.2 bits (112), Expect = 9e-05
Identities = 31/90 (34%), Positives = 39/90 (43%), Gaps = 4/90 (4%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSL 257
PY IT P G SV F C+VGG+P P V W++S G + K + L
Sbjct: 1082 PYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKL 1141
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYL 287
+ D GEY+ N G SAS L
Sbjct: 1142 VISMTFADDAGEYTIVVRNKHGETSASASL 1171
Score = 49.2 bits (112), Expect = 9e-05
Identities = 52/179 (29%), Positives = 71/179 (39%), Gaps = 32/179 (17%)
Query: 425 PEPIIAWYF-EGEALIQNHR--RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W E E + +H + L++KD+ + DSG Y+ A + G
Sbjct: 19853 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 19912
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKIGSSSILGYQV 540
++ V PGPP P + D + +LSW + G S+I Y V
Sbjct: 19913 VV----------------VMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIV 19956
Query: 541 EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
E SRG WV V +T V LIPG Y+F VR EN G+S P
Sbjct: 19957 EKCD-----------VSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEP 20004
Score = 49.2 bits (112), Expect = 9e-05
Identities = 97/385 (25%), Positives = 146/385 (37%), Gaps = 41/385 (10%)
Query: 178 YQCIARNAAG-----TRESAIATLKIHIKPYLIT-GP---EDVVAQTGSSVTFQCRVGGD 228
++ IARNAAG + + T + + P I+ P + +V G S + G
Sbjct: 23438 FRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGK 23497
Query: 229 PLPDVLWRRSAGG-GNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGY 286
P+P + W + N +K D SL + + + D G Y +A+N G S +
Sbjct: 23498 PIPTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVN 23557
Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR---DK 343
+ V D P P V SG A CT +P P +G II + R +
Sbjct: 23558 VKVLDRPG---PPEGPVVISGVTAE-KCTLAWKP-PLQ----DGGSDIINYIVERRETSR 23608
Query: 344 YHATAVFDGVTVLTINDTDKNDSRN-TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN 402
T V V L+ T + T AVN G V + + P
Sbjct: 23609 LVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPK 23668
Query: 403 GPSNQTLPIKSM-AVFPCTAICTPEPIIAWYF-----EGEALIQNHRRNVTNDGTLVLKD 456
P T+ SM V+ A I+ + EG + H+R + G L L+
Sbjct: 23669 APEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI---GELRLRV 23725
Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516
++ Y S+ + A + P P+ + +A D PGPP P ++T
Sbjct: 23726 TGLIENHDYEFRVSAEN-------AAGLSEPSPPSA-YQKACDPIYKPGPPNNPKVIDIT 23777
Query: 517 DTSVTLSWSQNNKIGSSSILGYQVE 541
+SV LSWS+ G I GY VE
Sbjct: 23778 RSSVFLSWSKPIYDGGCEIQGYIVE 23802
Score = 48.8 bits (111), Expect = 1e-04
Identities = 64/264 (24%), Positives = 102/264 (38%), Gaps = 33/264 (12%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
DVTV + A C + + W KG ++ S I+ A G + + D
Sbjct: 12421 DVTVPERRQARFECVLTREAN--VIWSKGPDIIKSSDKFDII-ADGKKHILVINDSQFDD 12477
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
GVY E +AR L V +R +F E + +G+T C + +
Sbjct: 12478 EGVYTAEVEGKKTSAR-----LFVTGIRLKFMSPLEDQTVKEGETATFVC--ELSHEKMH 12530
Query: 140 VYWKKN------GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
V W KN +T+L + + H ++ + + D Q A + S+
Sbjct: 12531 VVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIKAQVKEL----------SST 12580
Query: 194 ATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
A LK+ PY D A +T +C V D +P V W + G +P + +
Sbjct: 12581 AQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKD-VP-VKWFKD-GEEIVPSPKYSIK 12637
Query: 253 DDGS---LRLDNVILADEGEYSCE 273
DG L++ L D+GEY C+
Sbjct: 12638 ADGLRRILKIKKADLKDKGEYVCD 12661
Score = 48.8 bits (111), Expect = 1e-04
Identities = 86/376 (22%), Positives = 146/376 (38%), Gaps = 62/376 (16%)
Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNV 304
V+ D SL + + + ++ A N+VG VY+ PP I L P + +
Sbjct: 19779 VVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKI-LMPEQITI 19837
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
++G R G+P PT W +G ++ + A D ++L I D +
Sbjct: 19838 KAGKKLRIEAHVYGKPHPTCKWK-KGEDEVV-----TSSHLAVHKADSSSILIIKDVTRK 19891
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
DS +A N +G+ + K+ V D P GP I + C+
Sbjct: 19892 DS-GYYSLTAENSSGTDTQKIKVVVM---DAP------GPPQPPFDISDIDADACS---- 19937
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS-----SRHGKYV-- 477
++W+ +++ N+TN +++ D S T +AS R GK +
Sbjct: 19938 ----LSWHIP----LEDGGSNITN---YIVEKCDVSRGDWVTALASVTKTSCRVGKLIPG 19986
Query: 478 --WSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTDTS---VTLSWSQNNKIG 531
+ + ++ + V+ P G P++P VT + + ++W + + G
Sbjct: 19987 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 20046
Query: 532 SSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR-VHQTHYVVKSLIPGITYMFIVRTE 590
S I+GY +E RNS WV V T Y L+ G+ Y F +
Sbjct: 20047 GSPIIGYLIE----------RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYAL 20096
Query: 591 NSHGLSGPSPVSDSVT 606
N G S PS ++ VT
Sbjct: 20097 NKAGSSPPSKPTEYVT 20112
Score = 48.4 bits (110), Expect = 2e-04
Identities = 39/114 (34%), Positives = 53/114 (46%), Gaps = 12/114 (10%)
Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
A D P P KPI +VT S+ + W++ GS ILGY +E RE N
Sbjct: 15823 AKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP-ILGYWLE--KREV--------N 15871
Query: 557 SRGWVVIARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
S W + + + + V L+ G+TY+F V EN+ G SP SD T D
Sbjct: 15872 STHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHD 15925
Score = 47.6 bits (108), Expect = 3e-04
Identities = 34/97 (35%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRY 178
G+T VLE RG P P+V W K+G+ L + +RM + + LV++D +TD G+Y
Sbjct: 25649 GETFVLEA-DIRGKPIPDVVWSKDGKE-LEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 25706
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215
N GT+ I T+K+ +P GP V T
Sbjct: 25707 ILKLSNVGGTKSIPI-TVKVLDRPGPPEGPLKVTGVT 25742
Score = 47.2 bits (107), Expect = 4e-04
Identities = 54/218 (24%), Positives = 82/218 (37%), Gaps = 27/218 (12%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D G P I++ + ++ ATL+ G P P I+W+ GVL+ +
Sbjct: 3495 DSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTPSADYKFVFD 3554
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTA-------------RSRNATLHVAVLRE-- 108
G L ++ D G Y C A+N YG ++ AV +
Sbjct: 3555 GDDHSLIILFTKL-EDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLE 3613
Query: 109 --------EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHL 159
F E + + AQG + E G P P V W K+N Q + +H
Sbjct: 3614 KLGGPCPPHFLKELKPIRCAQGLPAIFE-YTVVGEPAPTVTWFKENKQLCTSVYYTIIHN 3672
Query: 160 VDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
+G G ++ D ++ D+G Y C A N G A L
Sbjct: 3673 PNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELL 3710
Score = 47.2 bits (107), Expect = 4e-04
Identities = 32/109 (29%), Positives = 54/109 (49%), Gaps = 15/109 (13%)
Query: 506 PPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV- 561
PP+ P+ +VTD + ++W K G S I+GY VE+ P + W+
Sbjct: 15211 PPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEM----------CPVGTEKWMR 15260
Query: 562 VIARRVHQTHY-VVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
V +R + + V + ++P Y+ VR N+ G+S PS +S++V D
Sbjct: 15261 VNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 15309
Score = 47.2 bits (107), Expect = 4e-04
Identities = 45/169 (26%), Positives = 68/169 (40%), Gaps = 18/169 (10%)
Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRH---GKYVWSGALLVDSPINPNIHFFRAADV 500
R V D + +D D+ + + +S GKY +L + +P F V
Sbjct: 19568 RKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKY----SLTLVNPAGEKAVFVNVR-V 19622
Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
PGP + +VT TS +SW+ G S + Y VE RE + + W
Sbjct: 19623 LDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVE--KREA--------DRKTW 19672
Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+ V +T + V +L+PG Y F V N +G P+ V V D
Sbjct: 19673 STVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASD 19721
Score = 47.2 bits (107), Expect = 4e-04
Identities = 61/260 (23%), Positives = 101/260 (38%), Gaps = 36/260 (13%)
Query: 357 TINDTDKNDSRNTIVCSAVNYAG---SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
T+ +N N +C A+N G + + G + V + PP I + + + +++
Sbjct: 25991 TVTKLKENTEYNFRIC-AINSEGVGEPATLPGSV-VAQERIEPPEIELDADLRKVVVLRA 26048
Query: 414 MAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVAS 470
A T PEP + W L + VT+ T LV+ ++ + DSG Y
Sbjct: 26049 SATLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLE 26108
Query: 471 SRHG-KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+ G K + ++DSP P V SVTLSW
Sbjct: 26109 NNSGSKTAFVNVRVLDSP-----------------SAPVNLTIREVKKDSVTLSWEPPLI 26151
Query: 530 IGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRT 589
G + I Y VE RET + + I +T + +++L G +Y F V
Sbjct: 26152 DGGAKITNYIVE--KRET--------TRKAYATITNNCTKTTFRIENLQEGCSYYFRVLA 26201
Query: 590 ENSHGLSGPSPVSDSVTVGD 609
N +G+ P+ ++ V V +
Sbjct: 26202 SNEYGIGLPAETTEPVKVSE 26221
Score = 46.4 bits (105), Expect = 6e-04
Identities = 54/219 (24%), Positives = 92/219 (42%), Gaps = 12/219 (5%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP + V V AT G P P + W++ G ++ + T + +
Sbjct: 4 QAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRA 63
Query: 70 RATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVL 127
+ T V +++G Y +ATN G A S L A F +S QG V L
Sbjct: 64 KLTIPAVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRL 123
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAA 186
+ + G P P V + ++G + D ++ D +L+I +A D+G Y A N+
Sbjct: 124 Q-VRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYSVNATNSV 182
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
G R ++ A L L+ G E+V A+ ++ ++
Sbjct: 183 G-RATSTAEL-------LVQGEEEVPAKKTKTIVSTAQI 213
Score = 46.4 bits (105), Expect = 6e-04
Identities = 36/116 (31%), Positives = 53/116 (45%), Gaps = 13/116 (11%)
Query: 496 RAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPR 555
+A D +P P +PI VT S ++W++ + G I Y +E RET+S
Sbjct: 17931 KAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHD-GGKPITNYILE--KRETMS------ 17981
Query: 556 NSRGWVVIARR-VHQ-THYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+ W + + +H T + V L+ G Y F V EN G+ PSP S V D
Sbjct: 17982 --KRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKD 18035
Score = 46.4 bits (105), Expect = 6e-04
Identities = 34/110 (30%), Positives = 50/110 (45%), Gaps = 11/110 (10%)
Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
V+ +P PP K +VT SV+LSW++ G S I+ Y VE+ ++S
Sbjct: 24054 VAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEM----------QAKHSEK 24103
Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
W A RV V+ +L G Y+F V N G S P ++ + D
Sbjct: 24104 WSECA-RVKSLQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKD 24152
Score = 46.0 bits (104), Expect = 8e-04
Identities = 32/102 (31%), Positives = 43/102 (42%), Gaps = 3/102 (2%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P ++ +VTV + TL C G PSP + WY+ + S I G+ L
Sbjct: 943 PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE 113
D+G + C A N GT S + L V V EEF E
Sbjct: 1003 REA-FAEDSGRFTCSAVNEAGTV-STSCYLAVQV-SEEFEKE 1041
Score = 46.0 bits (104), Expect = 8e-04
Identities = 51/177 (28%), Positives = 77/177 (43%), Gaps = 29/177 (16%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
PEP I W EG+ L++ R ++ ++DL + + V + HGKY+ S
Sbjct: 18863 PEPDITWTKEGKVLVREKRVDL-------IQDLPRVELQIKEAVRAD-HGKYIISAK--- 18911
Query: 485 DSPINPNIHFFRAADVSSL--PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
N + H +A V+ L PGP NVT + T+SW G S I + VE
Sbjct: 18912 ----NSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEY 18967
Query: 543 FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
P N +GW ++A V + + +L+ Y F V EN G+ GP+
Sbjct: 18968 ---------RKP-NQKGWSIVASDVTK-RLIKANLLANNEYYFRVCAENKVGV-GPT 19012
Score = 46.0 bits (104), Expect = 8e-04
Identities = 33/106 (31%), Positives = 48/106 (45%), Gaps = 10/106 (9%)
Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
PP KP+ N+T +VTL W++ G I Y VE R+ +G N
Sbjct: 22286 PPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVE--KRDLPNGRWLKAN-------FS 22336
Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
+ + + V L Y F V +N+ G +S PS SD++T DD
Sbjct: 22337 NILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDD 22382
Score = 45.6 bits (103), Expect = 0.001
Identities = 33/106 (31%), Positives = 43/106 (40%), Gaps = 10/106 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P PP N+T + L W+ K G S I Y VE R+ +GW +
Sbjct: 15011 PSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVE--KRDV--------RRKGWQTV 15060
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
V T V L G Y+F V EN+ G S + + DSV D
Sbjct: 15061 DTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKD 15106
Score = 45.6 bits (103), Expect = 0.001
Identities = 33/103 (32%), Positives = 44/103 (42%), Gaps = 9/103 (8%)
Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
A D P PP HN T ++T++W G S I+GY +E ++ R
Sbjct: 15500 AQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAK---GEERWKRC 15556
Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
+ V I Y K L G Y F VR EN+ G+S PS
Sbjct: 15557 NEHLVPILT------YTAKGLEEGKEYQFRVRAENAAGISEPS 15593
Score = 45.6 bits (103), Expect = 0.001
Identities = 63/250 (25%), Positives = 89/250 (35%), Gaps = 40/250 (16%)
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS--NQTLPIKS--MAVFPCTAICTPEPII 429
AVN G S L V DD PP I S T+ +K+ P P P I
Sbjct: 16298 AVNEIGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKI 16357
Query: 430 AWYFEGEALIQN--HRRNVTNDGT--------LVLKDLDKSDSGTYTCVASSRHGKYVWS 479
W + E +I+ +T + L + + D GTYT AS+R G
Sbjct: 16358 EWS-KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGS---- 16412
Query: 480 GALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQ 539
+ N+H +V P PP ++ S L+W G S I Y
Sbjct: 16413 --------VFRNVH----VEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYV 16460
Query: 540 VEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
++ + R W + + Y + LIP Y F VR N +G+S
Sbjct: 16461 IDK--------RDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDEC 16512
Query: 600 PVSDSVTVGD 609
SD V + D
Sbjct: 16513 K-SDKVVIQD 16521
Score = 45.6 bits (103), Expect = 0.001
Identities = 78/327 (23%), Positives = 130/327 (39%), Gaps = 32/327 (9%)
Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
A D PGPP+ P + T +S++L W K G S I GY VE+ T
Sbjct: 16625 AGDPIFPPGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEP 16684
Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD--DSNSL 614
+ + VV +L Y F V+ N G S PS + + D + +
Sbjct: 16685 D-------KLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEV 16737
Query: 615 WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNI 674
+ G + + I +I+ P T K WE + + + +I
Sbjct: 16738 FIDIGAQDCLVCKAGSQI-RIPAVIKGRP----TPKSSWE----FDGKAKKAMKDGVHDI 16788
Query: 675 TIEYEMKTILHSNDVSGFEITSLRKYT-KYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
+ +++T +S+ + E R +T KY I K K +N RV + DVP G
Sbjct: 16789 PEDAQLETAENSSVIIIPECK--RSHTGKYS---ITAKNKAGQKTANCRV--KVMDVP-G 16840
Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793
PP ++++ + + L W P+ I GY + +D K+ +N +T
Sbjct: 16841 PPKDLKVSDITRGSCRLSWKMPD-DDGGDRIKGYVIEKRTID---GKAWTKVNPDC-GST 16895
Query: 794 SLIMTNLTSGVSYSVQIAAETIIGLGP 820
+ ++ +L S Y ++ AE G+GP
Sbjct: 16896 TFVVPDLLSEQQYFFRVRAENRFGIGP 16922
Score = 45.2 bits (102), Expect = 0.001
Identities = 48/198 (24%), Positives = 82/198 (41%), Gaps = 16/198 (8%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN--RTIIFPGMSRDKYHATAVF 350
P+ SV V G+ A F +G P P + W +G T PG+ +
Sbjct: 6 PTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQ------ISFS 59
Query: 351 DGVTVLTINDTDK-NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
DG LTI K N R ++ A N +G + +L V ++ PP + T+
Sbjct: 60 DGRAKLTIPAVTKANSGRYSL--KATNGSGQATSTAELLVKAET--APPNFVQRLQSMTV 115
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYT 466
S P P++ +Y +G + + ++ +G +L++ + DSGTY+
Sbjct: 116 RQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTYS 175
Query: 467 CVASSRHGKYVWSGALLV 484
A++ G+ + LLV
Sbjct: 176 VNATNSVGRATSTAELLV 193
Score = 45.2 bits (102), Expect = 0.001
Identities = 49/209 (23%), Positives = 81/209 (38%), Gaps = 31/209 (14%)
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
++ ++ G+VA + T G P+P + W G ++ + K+ VFDG I
Sbjct: 3510 SNADISMGDVATLSVTVIGIPKPKIQWFFNG---VLLTPSADYKF----VFDGDDHSLII 3562
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTS------DDDRPPPIITN-----GPS--- 405
K + C A N G + L + S D + + + GP
Sbjct: 3563 LFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPPH 3622
Query: 406 --NQTLPIKSM----AVFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLK 455
+ PI+ A+F T + P P + W+ E + L + N GT ++
Sbjct: 3623 FLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVN 3682
Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLV 484
D + DSG Y C A + G+ + LLV
Sbjct: 3683 DPQREDSGLYICKAENMLGESTCAAELLV 3711
Score = 45.2 bits (102), Expect = 0.001
Identities = 36/111 (32%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
D LPGPP KP T S+ +SW+ G S I GY +E RE R SR
Sbjct: 16521 DPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLE--KREE-GSPYWSRVSR 16577
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+ + + V L+ G+ Y F N+ G+ PS SD GD
Sbjct: 16578 A-PITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGD 16627
Score = 45.2 bits (102), Expect = 0.001
Identities = 34/126 (26%), Positives = 55/126 (43%), Gaps = 6/126 (4%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD---GSLRLDN 261
+T + + + G ++ RV G P PD+ W + G + RV ++ D L++
Sbjct: 18839 VTCRDVITVRVGQTIRILARVKGRPEPDITWTKE-GKVLVREKRVDLIQDLPRVELQIKE 18897
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVESGNVARFTCTATGR 319
+ AD G+Y A+NS G S + V D P NL +V E+ ++ G
Sbjct: 18898 AVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENPLDNGG 18957
Query: 320 PEPTMF 325
E T F
Sbjct: 18958 SEITNF 18963
Score = 45.2 bits (102), Expect = 0.001
Identities = 36/136 (26%), Positives = 57/136 (41%), Gaps = 6/136 (4%)
Query: 164 NLVIQDARQTDAGRYQCIARNAAGT---RES-AIATLKIHIKPYLITGPEDVVAQTGSSV 219
+LV+ ++ +++ ARNA G RE+ + K + P I PE + + G +
Sbjct: 19784 SLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKL 19843
Query: 220 TFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
+ V G P P W++ + L K L + +V D G YS AENS
Sbjct: 19844 RIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 19903
Query: 278 VGAVSASGYLTVYDPP 293
G + + V D P
Sbjct: 19904 SGTDTQKIKVVVMDAP 19919
Score = 45.2 bits (102), Expect = 0.001
Identities = 32/107 (29%), Positives = 51/107 (47%), Gaps = 12/107 (11%)
Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
PP KP N+T SVTL W++ G + GY VE + P S+ W+
Sbjct: 21203 PPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVE--------KRDLP--SKSWMKANH 21252
Query: 566 -RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
V + + V L+ G Y F +R +N+ G +S PS ++++ D+
Sbjct: 21253 VNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIICKDE 21299
Score = 45.2 bits (102), Expect = 0.001
Identities = 30/115 (26%), Positives = 49/115 (42%), Gaps = 12/115 (10%)
Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548
+P F++A D PGPP P + + +S++++W++ G S I GY VE+ E
Sbjct: 22668 SPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPE-- 22725
Query: 549 SGNNTPRNSRGWVVIA--RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
W ++ + T Y + L Y + NS GL P+ V
Sbjct: 22726 --------EDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 22772
Score = 45.2 bits (102), Expect = 0.001
Identities = 38/137 (27%), Positives = 60/137 (43%), Gaps = 11/137 (8%)
Query: 174 DAGRYQCIARNAAGT------RESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCR 224
D ++ IARNA GT I T ++ P + GPE ++ ++G S+ +
Sbjct: 28849 DRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKAL 28908
Query: 225 VGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
V G P+P V W + M + VL SL + + G Y+ EA+N+ G+
Sbjct: 28909 VQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAK 28968
Query: 283 ASGYLTVYDPPSINLSP 299
A + V D P + P
Sbjct: 28969 AEIKVKVQDTPGKVVGP 28985
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/79 (37%), Positives = 40/79 (50%), Gaps = 7/79 (8%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDG--SLRLDNVILADEGEY 270
G VTF C++ G PLP + W + G + G ++ L DG SLR+ V+ DEG Y
Sbjct: 1305 GMGVTFHCKMSGYPLPKIAWYKD--GKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIY 1362
Query: 271 SCEAENSVGAVSASGYLTV 289
+ A N G SG L V
Sbjct: 1363 TAFASNIKGNAICSGKLYV 1381
Score = 44.8 bits (101), Expect = 0.002
Identities = 89/362 (24%), Positives = 141/362 (38%), Gaps = 43/362 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV---DGGNLVIQDARQTDAGR 177
+GD V LE S E W K+GQ + R+H+V L+I+D + DAG
Sbjct: 2369 EGDIVQLEVKVSLESVEG--VWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGN 2424
Query: 178 YQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
Y + ++ + + IT +DV G+ +C+V + V W
Sbjct: 2425 YSFTIPALGLSTSGRVSVYSVDV----ITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYL 2480
Query: 238 SAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
+ P RV+ + G+ L ++ +DEG Y VG V + L+V
Sbjct: 2481 N-DEQIKPDDRVQAIVKGTKQRLVINRTHASDEGPYKL----IVGRVETNCNLSVEKIKI 2535
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
I + E+ NV F + W+ + I P S+ K A +T
Sbjct: 2536 IRGLRDLTCTETQNVV-FE-VELSHSGIDVLWNFKDKE--IKPS-SKYKIEAHGKIYKLT 2590
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
VL + D + + T YAG + GKLTV I+ ++QT+
Sbjct: 2591 VLNMMKDD--EGKYTF------YAGENITSGKLTVAGG------AISKPLTDQTVAESQE 2636
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTC-VAS 470
AVF C + P+ W +G+ L + +DG L++ D G YT VA+
Sbjct: 2637 AVFEC-EVANPDSKGEWLRDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEYTYKVAT 2695
Query: 471 SR 472
S+
Sbjct: 2696 SK 2697
Score = 44.8 bits (101), Expect = 0.002
Identities = 21/54 (38%), Positives = 30/54 (55%)
Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
+P +++A D PGPPT + T S+TL+W + G S ILGY VE+
Sbjct: 24832 SPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEI 24885
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/99 (31%), Positives = 43/99 (43%), Gaps = 11/99 (11%)
Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
++ P PP K +++ SV+L+W + G S I+ Y VE + +
Sbjct: 27298 ITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALE----------KGQKN 27347
Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
WV A TH+VV L Y F V EN GLS P
Sbjct: 27348 WVKCA-VAKSTHHVVSGLRENSEYFFRVFAENQAGLSDP 27385
Score = 44.4 bits (100), Expect = 0.003
Identities = 32/109 (29%), Positives = 44/109 (40%), Gaps = 10/109 (9%)
Query: 501 SSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
+++P PP + T S+ L+W G S I GY VE PR S W
Sbjct: 14512 ATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVE----------RCPRGSDKW 14561
Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
V V +T V L G Y + V+ N G S PS ++ + D
Sbjct: 14562 VACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVD 14610
Score = 44.4 bits (100), Expect = 0.003
Identities = 29/115 (25%), Positives = 46/115 (40%), Gaps = 10/115 (8%)
Query: 495 FRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
F V P PP +T SV+++W G S I Y VE RE
Sbjct: 23952 FVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVE--KREA------- 24002
Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+ + + H+ + + L G +Y F V EN +G+ P+ +D + V +
Sbjct: 24003 -TRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAE 24056
Score = 44.0 bits (99), Expect = 0.003
Identities = 36/104 (34%), Positives = 50/104 (48%), Gaps = 13/104 (12%)
Query: 496 RAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTP 554
+A D PGPP K + H +V T V+L W++ ++ G S I GY VE + E
Sbjct: 18329 KALDPLHPPGPP-KDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE-YQEE-------- 18378
Query: 555 RNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
++ W+ + V VV L G TY F V+ EN GL P
Sbjct: 18379 -GTQDWIKF-KTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLP 18420
Score = 43.6 bits (98), Expect = 0.004
Identities = 33/129 (25%), Positives = 58/129 (44%), Gaps = 4/129 (3%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLV 166
F +P ++ +G +VV C G+P+P+VYWKK+G L ++ LV
Sbjct: 1084 FITKPVVQKLVEGGSVVFGC-QVGGNPKPHVYWKKSGVPLTTGYRYKVSYNKQTGECKLV 1142
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG 226
I DAG Y + RN G ++ + L+ L+ ++++ QT + Q
Sbjct: 1143 ISMTFADDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQQEMLYQTQVTAFVQEPKV 1202
Query: 227 GDPLPDVLW 235
G+ P ++
Sbjct: 1203 GETAPGFVY 1211
Score = 43.6 bits (98), Expect = 0.004
Identities = 56/215 (26%), Positives = 87/215 (40%), Gaps = 35/215 (16%)
Query: 275 ENSVGAVSASGYLTV--YDPPSINLSPN-----------SVNVESGNVARFTCTATGRPE 321
E A++ G +T+ + P I LSP+ S V G+ A F G+P+
Sbjct: 2047 EEEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPD 2106
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
P W G + D+ + D V L I D DS +I+ A+N AG +
Sbjct: 2107 PECEWYKNGVKI-----ERSDRIYWYWPEDNVCELVIRDVTAEDSA-SIMVKAINIAGET 2160
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIK---SMAVFPCTAICTPEPI--IAWYFEGE 436
L V + +IT Q + K +MA F C T EP + WY +G
Sbjct: 2161 SSHAFLLVQAKQ-----LITFTQELQDVVAKEKDTMATFECE---TSEPFVKVKWYKDGM 2212
Query: 437 ALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCV 468
+ + + + +D L + +D SD+ Y+CV
Sbjct: 2213 EVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCV 2247
Score = 43.6 bits (98), Expect = 0.004
Identities = 30/93 (32%), Positives = 46/93 (49%), Gaps = 5/93 (5%)
Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
P PP +E+ + T LKW+ PE ++G N +V DV K ++TTV
Sbjct: 15010 PPSPPRWLEVINITKNTADLKWTVPE---KDGGSPITNYIVEKRDV-RRKGWQTVDTTV- 15064
Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
+ T +T LT G Y ++AAE IG +++
Sbjct: 15065 KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE 15097
Score = 43.6 bits (98), Expect = 0.004
Identities = 75/327 (22%), Positives = 123/327 (37%), Gaps = 33/327 (10%)
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ ++G+ +GRP P + W +E R D+ T D T LT+ D+
Sbjct: 29584 ITCKAGSPFTIDVPISGRPAPKVTWKLEEMRL-----KETDRVSITTTKDRTT-LTVKDS 29637
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
+ DS + + N AG + V RP P+ GP + + S++ C
Sbjct: 29638 MRGDSGRYFL-TLENTAGVKTFSVTVVVIG---RPGPV--TGP----IEVSSVSAESCV- 29686
Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS-G 480
+ EP E I R + T LV + ++ + V S
Sbjct: 29687 LSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSEN 29746
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
V P+ V P PT+P ++V+ ++++ W + G S I+GY V
Sbjct: 29747 RFGVSKPLESAPIIAEHPFVP--PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWV 29804
Query: 541 EVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
E R T+ WV + + +Y V L+ G+ Y F N+ G+S S
Sbjct: 29805 EKKERNTIL----------WVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 29854
Query: 600 PVSDSVTVGD--DSNSLWEGTGVSNST 624
S + + D+ E T V+ ST
Sbjct: 29855 EASRPIMAQNPVDAPGRPEVTDVTRST 29881
Score = 43.2 bits (97), Expect = 0.006
Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 6/97 (6%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P PP K +T +V LSW G S + Y VE L+ + T W
Sbjct: 16939 PDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVEC-----LAWDPTGTKKEAWRQC 16993
Query: 564 ARR-VHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
+R V + + V+ L+ G Y F V+ N+ G+S PS
Sbjct: 16994 NKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPS 17030
Score = 43.2 bits (97), Expect = 0.006
Identities = 36/113 (31%), Positives = 48/113 (42%), Gaps = 10/113 (8%)
Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
A D + PGPP +T + T +S L WS K G S + GY VE + E G
Sbjct: 17342 ARDPIAPPGPPFPKVT-DWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEE---GKEEWEK 17396
Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+ + V T VV L G Y F V N G+ P V+D + + D
Sbjct: 17397 GKD-----KEVRGTKLVVTGLKEGAFYKFRVSAVNIAGIGEPGEVTDVIEMKD 17444
Score = 43.2 bits (97), Expect = 0.006
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 7/102 (6%)
Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
PP KP +VT ++V+L W++ G S I+GY VE L G+ R +
Sbjct: 20119 PPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACK---LPGDKWVRCN----TAPH 20171
Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
++ Q Y L Y F + +S PS SD VT+
Sbjct: 20172 QIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTI 20213
Score = 43.2 bits (97), Expect = 0.006
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 3/101 (2%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
GD + +E +P G P+P V WKK Q L ++ I + ++D+G Y
Sbjct: 22007 GDNIKVE-IPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPL 22065
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTF 221
ARN G + T+++H P TGP + VTF
Sbjct: 22066 TARNIVG-EVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTF 22105
Score = 43.2 bits (97), Expect = 0.006
Identities = 48/183 (26%), Positives = 73/183 (39%), Gaps = 29/183 (15%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALL 483
P P W L + T+ TL +++ +++D+G YT + G
Sbjct: 29312 PTPTAVWSKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSG--------- 29362
Query: 484 VDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGSSSILGYQVEV 542
+ +I F V PGPP PIT +VT S TL W G + I Y VE
Sbjct: 29363 -----SKSITF--TVKVLDTPGPPG-PITFKDVTRGSATLMWDAPLLDGGARIHHYVVE- 29413
Query: 543 FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVS 602
RE + R W VI+ + + + V L G+ Y F V N +G+ P +
Sbjct: 29414 -KREA--------SRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMP 29464
Query: 603 DSV 605
+ +
Sbjct: 29465 EPI 29467
Score = 42.7 bits (96), Expect = 0.008
Identities = 51/178 (28%), Positives = 67/178 (37%), Gaps = 8/178 (4%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAGGL 66
S EAP I E+ TV + A R G P P WYK GV + SD P +
Sbjct: 2074 SMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDNV 2133
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV- 125
L D+ +A N G S L A F E + + + DT+
Sbjct: 2134 CEL-VIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDTMA 2192
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDGGN-LVIQDARQTDAGRYQCI 181
EC P V W K+G + +GD RMH + L I +DA Y C+
Sbjct: 2193 TFEC--ETSEPFVKVKWYKDGME-VHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCV 2247
Score = 42.7 bits (96), Expect = 0.008
Identities = 29/98 (29%), Positives = 43/98 (43%), Gaps = 2/98 (2%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270
+V + G S G P P++ W R G + K ++ L +DN D G+Y
Sbjct: 24961 IVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKY 25020
Query: 271 SCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306
+ ENS G+ SA + V D P NL+ V +S
Sbjct: 25021 ILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDS 25058
Score = 42.3 bits (95), Expect = 0.010
Identities = 78/349 (22%), Positives = 128/349 (36%), Gaps = 36/349 (10%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASG---YLTVYDPPSINLSPNSVNVESGNVA 310
D + R+ +VI E ++ AEN G S L++ DP S P ++V
Sbjct: 15167 DCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAG-R 15225
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
+ A PE + G + P + + + + D +
Sbjct: 15226 KHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVL 15285
Query: 371 VCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
AVN G S + V D D P I + + +++ P P P
Sbjct: 15286 RVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSI-PVPFRAVPVPT 15344
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGALLVD 485
++W+ +G+ + + R + ND ++ KS D+G YT ++ G S
Sbjct: 15345 VSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATAS------ 15398
Query: 486 SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSR 545
IN V LPGP ++T +S L+W G + IL Y +E R
Sbjct: 15399 --IN--------VKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLE--RR 15446
Query: 546 ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
E +G T ++ + ++ + VK LIP Y F V+ N G
Sbjct: 15447 E--AGRRT------YIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVG 15487
Score = 42.3 bits (95), Expect = 0.010
Identities = 32/111 (28%), Positives = 53/111 (47%), Gaps = 7/111 (6%)
Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
A D PGPPT + T S+TL W + G + I+GY VE+ R ++ + +P
Sbjct: 19417 AKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEM--RPKIA-DASP-- 19471
Query: 557 SRGW--VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
GW A ++ + + V SL Y F V +N G+ P+ + +++
Sbjct: 19472 DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAI 19522
Score = 42.3 bits (95), Expect = 0.010
Identities = 34/107 (31%), Positives = 48/107 (44%), Gaps = 12/107 (11%)
Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA- 564
PP +P VT SVTL W + G S I GY VE +E G W+ +
Sbjct: 23368 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE--KKELPEGR--------WMKASF 23417
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGL-SGPSPVSDSVTVGDD 610
+ TH+ V L+ Y F V N+ G+ S PS + ++T D+
Sbjct: 23418 TNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 23464
Score = 41.9 bits (94), Expect = 0.013
Identities = 30/107 (28%), Positives = 46/107 (42%), Gaps = 11/107 (10%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P P V+ +T+ W+ G SI GY +E ++S WV +
Sbjct: 19323 PGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE----------KKEKHSTRWVPV 19372
Query: 564 AR-RVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+ + + V++L+P Y F V+ EN G+ PS S V D
Sbjct: 19373 NKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKD 19419
Score = 41.5 bits (93), Expect = 0.018
Identities = 24/69 (34%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQ 179
+G++V LEC G P P V W + + D ++ G L+I++A D+GR+
Sbjct: 956 EGESVTLEC-HISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRFT 1014
Query: 180 CIARNAAGT 188
C A N AGT
Sbjct: 1015 CSAVNEAGT 1023
Score = 41.5 bits (93), Expect = 0.018
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL---RLDNVILADE 267
+ + G++V V G P+P V W++ G P +K+ +L L +V D
Sbjct: 20232 LTVKAGTNVCLDATVFGKPMPTVSWKKD-GTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 20290
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPP 293
G+Y+ AENS G+ SA+ L V D P
Sbjct: 20291 GDYTITAENSSGSKSATIKLKVLDKP 20316
Score = 41.5 bits (93), Expect = 0.018
Identities = 37/132 (28%), Positives = 65/132 (49%), Gaps = 15/132 (11%)
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESK-----QSAQ-GDTVVLECLPPRGSPEPN 139
+A N G + R L V V+ ++ ++P K S Q G+ + +E +P G P PN
Sbjct: 25213 KAYNEKGKSDPR--VLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDLKIE-IPVIGRPRPN 25269
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
+ W K+G+ L +R+++ + L I++ + D G+Y A N+AGT ++ +
Sbjct: 25270 ISWVKDGEPL--KQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVI 25327
Query: 197 KIHIKPYLITGP 208
+ KP GP
Sbjct: 25328 VLE-KPGPPVGP 25338
Score = 41.5 bits (93), Expect = 0.018
Identities = 33/108 (30%), Positives = 46/108 (42%), Gaps = 12/108 (11%)
Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV-VIA 564
PP P +VT ++TL W+ + G S I+GY +E R+ GN WV
Sbjct: 28784 PPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE--KRQ---GNER------WVRCNF 28832
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612
V + Y V L PG Y F + N+ G P S + + D N
Sbjct: 28833 TDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDEN 28880
Score = 41.1 bits (92), Expect = 0.023
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 8/102 (7%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I L P V V G ARF C TG P+P + W + G + R +DG
Sbjct: 1841 PDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQ-------LIRKSKRFRVRYDG 1893
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
+ L I D D+ + +A N G + KL + +D
Sbjct: 1894 IHYLDIVDCKSYDT-GEVKVTAENPEGVIEHKVKLEIQQRED 1934
Score = 41.1 bits (92), Expect = 0.023
Identities = 45/186 (24%), Positives = 71/186 (38%), Gaps = 29/186 (15%)
Query: 425 PEPIIAWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P W F + L R + ++ LV+ ++SD G YT +R
Sbjct: 14349 PRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENR--------V 14400
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVE 541
+ I+ N V + P P + ++T SV L+W + G S + GY VE
Sbjct: 14401 KTISGEIDVN--------VIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVE 14452
Query: 542 VFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPV 601
RE + + W + V + V L+ G Y+F V N G P+ V
Sbjct: 14453 --KREV--------SRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYV 14502
Query: 602 SDSVTV 607
+ V +
Sbjct: 14503 DEPVNM 14508
Score = 41.1 bits (92), Expect = 0.023
Identities = 81/351 (23%), Positives = 130/351 (37%), Gaps = 39/351 (11%)
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVS----ASGYLT--VYDPPSINLSPNS---VNVES 306
+ R+ +I +E + +A N VG A + + PP + L + V
Sbjct: 18790 AFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDVITVRV 18849
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKND 365
G R GRPEP + W+ EG + R+K + D V L I + + D
Sbjct: 18850 GQTIRILARVKGRPEPDITWTKEGKVLV------REK-RVDLIQDLPRVELQIKEAVRAD 18902
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
I+ SA N +G + +G + + DRP P Q L + ++ CT I
Sbjct: 18903 HGKYII-SAKNSSGHA--QGS-AIVNVLDRPGPC-------QNLKVTNVTKENCT-ISWE 18950
Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
P+ E I +R+ ++V D+ K + + + + V
Sbjct: 18951 NPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIKANLLANNEYYFRVCAENKVGVG 19010
Query: 486 SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSR 545
I A + PG P + T V L W + + G S L Y VE R
Sbjct: 19011 PTIETKTPIL-AINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVE---R 19066
Query: 546 ETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
++ R +G + +THY+V + Y F V+T+N G S
Sbjct: 19067 RLKGSDDWERVHKG------SIKETHYMVDRCVENQIYEFRVQTKNEGGES 19111
Score = 41.1 bits (92), Expect = 0.023
Identities = 31/99 (31%), Positives = 45/99 (45%), Gaps = 4/99 (4%)
Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSC 272
+ G S+ + G P P+V W + G + V SL LDNV D G+Y+
Sbjct: 23882 RAGGSLRLFVPIKGRPTPEVKWGK-VDGEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTL 23940
Query: 273 EAENSVGAVSASGYLTVYDPPS--INLSPNSVNVESGNV 309
ENS G SA + V D PS +NL + +S ++
Sbjct: 23941 TLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSI 23979
Score = 40.7 bits (91), Expect = 0.031
Identities = 55/220 (25%), Positives = 72/220 (32%), Gaps = 35/220 (15%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLR 258
P I + G T V G P P + W + G P K + DD SL
Sbjct: 3503 PIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFN-GVLLTPSADYKFVFDGDDHSLI 3561
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD-------------------------PP 293
+ L DEGEY+C A N G S YL + PP
Sbjct: 3562 ILFTKLEDEGEYTCMASNDYGKTICSAYLKINSKGEGHKDTETESAVAKSLEKLGGPCPP 3621
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
+ G A F T G P PT+ W E + + Y +G
Sbjct: 3622 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQL-----CTSVYYTIIHNPNGS 3676
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
+ND + DS +C A N G S +L V +D
Sbjct: 3677 GTFIVNDPQREDS-GLYICKAENMLGESTCAAELLVLLED 3715
Score = 40.3 bits (90), Expect = 0.041
Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 2/96 (2%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS--LRLDNVILAD 266
E +V + G++V F + G P+P W D+ S L + N + D
Sbjct: 18445 EGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRD 18504
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
GEY N+ G+ + + +LTV D P P ++
Sbjct: 18505 TGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINI 18540
Score = 40.3 bits (90), Expect = 0.041
Identities = 18/56 (32%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGT 188
G P P WKK ++ +H D + L+I+D + D+G Y A N++GT
Sbjct: 19851 GKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 19906
Score = 40.3 bits (90), Expect = 0.041
Identities = 33/106 (31%), Positives = 47/106 (44%), Gaps = 10/106 (9%)
Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
PP +P N+T SV+L WS+ + G + I GY VE RE G N
Sbjct: 26614 PPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVE--RRELPDGRWLKCN-------YT 26664
Query: 566 RVHQTHYVVKSLIPGITYMFIVRTEN-SHGLSGPSPVSDSVTVGDD 610
+ +T++ V L Y F V N + +S PS + + V DD
Sbjct: 26665 NIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDD 26710
Score = 39.9 bits (89), Expect = 0.054
Identities = 39/141 (27%), Positives = 69/141 (48%), Gaps = 18/141 (12%)
Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPE-----SKQSAQ-GDTVVLECLPPRGSPEPNV 140
A N G RS +L V ++ ++ +EP+ S S Q G + +E +P G P+P +
Sbjct: 24132 AVNEKG--RSDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIE-VPISGRPKPTI 24188
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLV---IQDARQTDAGRYQCIARNAAGTRESAIATLK 197
W K+G L +R+++ D +L I++ + D G+Y N G + ++I +
Sbjct: 24189 TWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVT 24246
Query: 198 IHIKPYLITGP---EDVVAQT 215
+ KP GP +DV A++
Sbjct: 24247 LD-KPDPPKGPVKFDDVSAES 24266
Score = 39.5 bits (88), Expect = 0.072
Identities = 30/83 (36%), Positives = 37/83 (44%), Gaps = 3/83 (3%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
KP ++ PE V G + F+CRV G P P V W + G R +V DG LD
Sbjct: 1840 KPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLN-GQLIRKSKRFRVRYDGIHYLD 1898
Query: 261 NVILA--DEGEYSCEAENSVGAV 281
V D GE AEN G +
Sbjct: 1899 IVDCKSYDTGEVKVTAENPEGVI 1921
Score = 39.5 bits (88), Expect = 0.072
Identities = 30/92 (32%), Positives = 40/92 (43%), Gaps = 4/92 (4%)
Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
D P GPPIN + T+V KW PP L I Y + P ++ +V +T
Sbjct: 15727 DTP-GPPINFVFEDIRKTSVLCKWEPP-LDDGGSEIINYTLEKKDKTKPDSEWIVVTSTL 15784
Query: 789 VHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
H S +T L G Y ++ AE G GP
Sbjct: 15785 RHCKYS--VTKLIEGKEYLFRVRAENRFGPGP 15814
Score = 39.5 bits (88), Expect = 0.072
Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 5/130 (3%)
Query: 695 TSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWS 753
T L + +Y F + +G+P S + +D P GPP E+ + T + W
Sbjct: 21461 TKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWK 21520
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
P + ITGY+ V + + + + AI T V + T L G +Y +++AE
Sbjct: 21521 RP-VDDGGSEITGYH--VERREKKSLRWVRAIKTPVSDLRCKV-TGLQEGSTYEFRVSAE 21576
Query: 814 TIIGLGPFSQ 823
G+GP S+
Sbjct: 21577 NRAGIGPPSE 21586
Score = 39.5 bits (88), Expect = 0.072
Identities = 29/99 (29%), Positives = 49/99 (49%), Gaps = 4/99 (4%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGE 269
VV + +++ + G P P+V W + A G +++V + L +DNV D G
Sbjct: 26044 VVLRASATLRLFVTIKGRPEPEVKWEK-AEGILTDRAQIEVTSSFTMLVIDNVTRFDSGR 26102
Query: 270 YSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306
Y+ EN+ G+ +A + V D PS +NL+ V +S
Sbjct: 26103 YNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDS 26141
Score = 39.1 bits (87), Expect = 0.095
Identities = 53/234 (22%), Positives = 86/234 (36%), Gaps = 39/234 (16%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-----SVEGN------------RTI 334
PP++ +V V G C +G P PT+ W +E + R +
Sbjct: 942 PPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLM 1001
Query: 335 IFPGMSRD--KYHATAVFDGVTV-----LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
I + D ++ +AV + TV L + +++ + T V FV +
Sbjct: 1002 IREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQVSEEFEKETTAVTEKFTTEEKRFVESRD 1061
Query: 388 TVTSDD----------DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
V +D + P P Q L VF C P+P + W G
Sbjct: 1062 VVMTDTSLTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVP 1121
Query: 438 LIQNHRRNV-----TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
L +R V T + LV+ D+G YT V ++HG+ S +LL ++
Sbjct: 1122 LTTGYRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASLLEEA 1175
Score = 39.1 bits (87), Expect = 0.095
Identities = 41/198 (20%), Positives = 81/198 (40%), Gaps = 12/198 (6%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD-THRSILPAGGLFFLR 70
P + +P+ Q A + + G P P W+ G +V+D TH+ ++ G L
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR---LEPESKQSAQGDTVVL 127
SD+G + A N G + S + L V + + + +E + + + +
Sbjct: 1517 IVPA-TPSDSGEWTVVAQNRAGRS-SISVILTVEAVEHQVKPMFVEKLKNVNIKEGSQLE 1574
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG----GNLVIQDARQTDAGRYQCIAR 183
+ G+P P++ W KN ++ ++ ++G L I D+ Y A
Sbjct: 1575 MKVRATGNPNPDIVWLKNSDIIVPHKYPKIR-IEGTKGEAALKIDSTVSQDSAWYTATAI 1633
Query: 184 NAAGTRESAIATLKIHIK 201
N AG R++ + + ++
Sbjct: 1634 NKAG-RDTTRCKVNVEVE 1650
Score = 39.1 bits (87), Expect = 0.095
Identities = 32/112 (28%), Positives = 55/112 (49%), Gaps = 11/112 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAG--GSPSPAIRW-YKGGVLVVSDTHRSILPAGGL 66
+ P+ ++ + + R PA CR G P+ + W + G L ++ R I G
Sbjct: 1701 QKPFFKKKLTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFG-- 1758
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK 117
+ +G +S D+G+ C ATN YGT + +ATL ++++E L ES+
Sbjct: 1759 -YCSLDYGVAYSRDSGIITCRATNKYGTDHT-SATL---IVKDEKSLVEESQ 1805
Score = 39.1 bits (87), Expect = 0.095
Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 5/84 (5%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL---VDGGNLVIQDARQTDAGRY 178
GDT+ LE RG P P V W K+ R+ + D + A+++D G+Y
Sbjct: 19143 GDTIRLEA-GVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGGKY 19201
Query: 179 QCIARNAAGTRESAIATLKIHIKP 202
A N AG+ A AT+ + KP
Sbjct: 19202 VVTATNTAGS-FVAYATVNVLDKP 19224
Score = 39.1 bits (87), Expect = 0.095
Identities = 37/132 (28%), Positives = 59/132 (44%), Gaps = 11/132 (8%)
Query: 692 FEITSLRKYTKYEFFLIPF--YKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
F +T L + +Y F + Y EG S VA+ DVPD PP + + +V
Sbjct: 21062 FRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPP-NIVDVRHDSVS 21120
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV--AINTTVHQATSLIMTNLTSGVSYS 807
L W+ P+ + ITGY+ L+ S++ N T + +T LT G+ Y
Sbjct: 21121 LTWTDPK-KTGGSPITGYH-----LEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYE 21174
Query: 808 VQIAAETIIGLG 819
++ A + G+G
Sbjct: 21175 FRVMAINLAGVG 21186
Score = 39.1 bits (87), Expect = 0.095
Identities = 29/105 (27%), Positives = 47/105 (44%), Gaps = 8/105 (7%)
Query: 499 DVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
D + PGPP+ P + T S +L+W + + G I GY VE + + +++
Sbjct: 21595 DAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVE---HQKVGDEAWIKDTT 21651
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
G A R+ T +VV L Y F + N G+ P+ + D
Sbjct: 21652 G---TALRI--TQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPD 21691
Score = 38.7 bits (86), Expect = 0.13
Identities = 69/306 (22%), Positives = 114/306 (37%), Gaps = 19/306 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
EA I + ++TV Q A ++W K GV++ S+ +I G ++ L
Sbjct: 2705 EAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSL 2764
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
R + + D VY +AR LHV ++ +P+ + + TV E
Sbjct: 2765 RIKNCAI-VDESVYGFRLGRLGASAR-----LHVETVK--IIKKPKDVTALENATVAFE- 2815
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
+ P ++ KN + D + L++Q+ +DAG Y +
Sbjct: 2816 VSVSHDTVPVKWFHKNVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLECKA 2875
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
+ + TL I I PE A +F+C V +P +W ++ M +
Sbjct: 2876 KLFVETLHITKTMKNIEVPETKTA------SFECEVSHFNVPS-MWLKNGVEIEMS-EKF 2927
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
K++ G L +I+ E S E G S LTV P I +N E +
Sbjct: 2928 KIVVQGKLH-QLIIMNTSTEDSAEYTFVCGNDQVSATLTV-TPIMITSMLKDINAEEKDT 2985
Query: 310 ARFTCT 315
F T
Sbjct: 2986 ITFEVT 2991
Score = 38.7 bits (86), Expect = 0.13
Identities = 25/89 (28%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
P GPP ++ ++ T V L W+ P+ ITGY +V + + + + T +
Sbjct: 18336 PPGPPKDLHHVDVDKTEVSLVWNKPDRD-GGSPITGY--LVEYQE-EGTQDWIKFKTVTN 18391
Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLG 819
++T L G +Y ++ AE I+GLG
Sbjct: 18392 --LECVVTGLQQGKTYRFRVKAENIVGLG 18418
Score = 38.7 bits (86), Expect = 0.13
Identities = 29/112 (25%), Positives = 49/112 (43%), Gaps = 9/112 (8%)
Query: 87 ATNSYGTARSRNATLHVAVLREEFR-----LEPESKQSAQ---GDTVVLECLPPRGSPEP 138
A N+ G + + + + ++E+ L+P K GDT+VL + G P P
Sbjct: 21277 AKNTAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLP 21336
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTR 189
W K G+ + +++ + L I+ A + DAG Y A N GT+
Sbjct: 21337 KSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTK 21388
Score = 38.7 bits (86), Expect = 0.13
Identities = 48/186 (25%), Positives = 75/186 (40%), Gaps = 17/186 (9%)
Query: 41 PAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV--HSDAGVYWCEATNSYGTARSRN 98
P RW K + DTH + GL RV + AGV+ E + S G +R+
Sbjct: 23408 PEGRWMKASFTNIIDTHFEVT---GLVEDHRYEFRVIARNAAGVF-SEPSESTGAITARD 23463
Query: 99 ATLHVAVLREEFRLEPESKQSA---QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
V ++P+ K + G++ ++ G P P + W K Q L
Sbjct: 23464 E-----VDPPRISMDPKYKDTIVVHAGESFKVDA-DIYGKPIPTIQWIKGDQELSNTARL 23517
Query: 156 RMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ 214
+ D +L ++DA + D+G Y A+N AG R S +K+ +P GP +
Sbjct: 23518 EIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGER-SVTVNVKVLDRPGPPEGPVVISGV 23576
Query: 215 TGSSVT 220
T T
Sbjct: 23577 TAEKCT 23582
Score = 38.7 bits (86), Expect = 0.13
Identities = 32/107 (29%), Positives = 47/107 (43%), Gaps = 12/107 (11%)
Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA- 564
PP +P +T +VTL W + G S I GY VE ++ G W+ +
Sbjct: 25532 PPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVE--KKDLPDGR--------WMKASF 25581
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
V +T + V L+ Y F V N+ G S PS S ++T D+
Sbjct: 25582 TNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDE 25628
Score = 38.7 bits (86), Expect = 0.13
Identities = 29/98 (29%), Positives = 48/98 (48%), Gaps = 6/98 (6%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
G P P + W K+ + L + + + D +++I+DA + ++G Y+ RNA G SA
Sbjct: 27825 GKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMG---SA 27881
Query: 193 IATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGD 228
AT+++ I KP GP + T +T R D
Sbjct: 27882 SATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPAD 27919
Score = 38.3 bits (85), Expect = 0.17
Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 11/117 (9%)
Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
A D + PGPP +VT V L W G I Y +E +E L
Sbjct: 15104 AKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIE--KKERLGTR----- 15156
Query: 557 SRGWVVIARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612
WV + ++ V +I G F VR EN G+ PS ++ +++ D ++
Sbjct: 15157 ---WVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTS 15210
Score = 38.3 bits (85), Expect = 0.17
Identities = 33/113 (29%), Positives = 50/113 (44%), Gaps = 11/113 (9%)
Query: 497 AADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRN 556
A D S PGPP +T + + T++ L W G I+GY V+ ++ + N R
Sbjct: 15923 AHDPISPPGPPIPRVT-DTSSTTIELEWEPPAFNGGGEIVGYFVD---KQLVGTNEWSRC 15978
Query: 557 SRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+ + +V Q Y VK + G Y V N+ G GP + VTV +
Sbjct: 15979 TEKMI----KVRQ--YTVKEIREGADYKLRVSAVNAAG-EGPPGETQPVTVAE 16024
Score = 38.3 bits (85), Expect = 0.17
Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 5/92 (5%)
Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
D+P P I+ +++ V W PPE +G + N VV + + V + TT
Sbjct: 22084 DIPGPPTGPIKFDEVSSDFVTFSWDPPE---NDGGVPISNYVVEMRQTDST-TWVELATT 22139
Query: 789 VHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
V + T+ T LT+G+ Y ++ A+ G+GP
Sbjct: 22140 VIR-TTYKATRLTTGLEYQFRVKAQNRYGVGP 22170
Score = 38.3 bits (85), Expect = 0.17
Identities = 27/91 (29%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
D P PP+N+++ + +V + W PP L +G N +V + KS A+ T
Sbjct: 23959 DTPS-PPVNLKVTEITKDSVSITWEPP---LLDGGSKIKNYIVEKREA-TRKSYAAVVTN 24013
Query: 789 VHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
H+ S + L G SY ++ AE G+G
Sbjct: 24014 CHK-NSWKIDQLQEGCSYYFRVTAENEYGIG 24043
Score = 38.3 bits (85), Expect = 0.17
Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 6/81 (7%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRE 190
G P P + W K+G + + +R ++ N L ++D + D G+Y +N AGTR
Sbjct: 26742 GRPLPVISWAKDG--IEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRS 26799
Query: 191 SAIATLKIHIKPYLITGPEDV 211
A+ K+ KP GP ++
Sbjct: 26800 VAV-NCKVLDKPGPPAGPLEI 26819
Score = 38.3 bits (85), Expect = 0.17
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+P +G P P V W+K+ + L D + D +L+ I + D G+Y N G
Sbjct: 28220 IPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGE 28279
Query: 189 RESAIATLKI 198
+S+ ++K+
Sbjct: 28280 PKSSTVSVKV 28289
Score = 38.3 bits (85), Expect = 0.17
Identities = 28/102 (27%), Positives = 51/102 (50%), Gaps = 7/102 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD---GGNLVIQDARQTDAGRY 178
G+++ ++ L +G P P V W K+G + + M + D +L ++DA + G Y
Sbjct: 28900 GESLRIKALV-QGRPVPRVTWFKDGVEI--EKRMNMEITDVLGSTSLFVRDATRDHRGVY 28956
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVT 220
A+NA+G+ ++ I +K+ P + GP TG +T
Sbjct: 28957 TVEAKNASGSAKAEI-KVKVQDTPGKVVGPIRFTNITGEKMT 28997
Score = 37.9 bits (84), Expect = 0.22
Identities = 77/332 (23%), Positives = 130/332 (39%), Gaps = 52/332 (15%)
Query: 291 DPPSINLSPN---SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
+PP++ L + + + +G R TGRP PT W+ E + +D+
Sbjct: 16027 EPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGE------LDKDR---- 16076
Query: 348 AVFDGV---TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
V D V + L I D + D V +A N GS F ++ V D P P++ P
Sbjct: 16077 VVIDNVGTKSELIIKDALRKD-HGRYVITATNSCGSKFAAARVEVF---DVPGPVLDLKP 16132
Query: 405 --SNQTLPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNV-TNDGTLVLKDLDKS 460
+N+ + + + + I + E +A + R+ + T + L +
Sbjct: 16133 VVTNRKMCLLNWSDPEDDG---GSEITGFIIERKDAKMHTWRQPIETERSKCDITGLLEG 16189
Query: 461 DSGTYTCVASSRH--GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDT 518
+ +A ++ G V G +L P+ P P P + T +
Sbjct: 16190 QEYKFRVIAKNKFGCGPPVEIGPILAVDPLGP-------------PTSPERLTYTERTKS 16236
Query: 519 SVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLI 578
++TL W + G S I GY +E R ++ P R V R T ++V++L
Sbjct: 16237 TITLDWKEPRSNGGSPIQGYIIE--KRR----HDKPDFER---VNKRLCPTTSFLVENLD 16287
Query: 579 PGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
Y F V+ N G S PS + +V + DD
Sbjct: 16288 EHQMYEFRVKAVNEIGESEPS-LPLNVVIQDD 16318
Score = 37.9 bits (84), Expect = 0.22
Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 4/100 (4%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV---LDDGSLRLDNVILAD 266
+ + G ++ + V G P P+V W + ++ RVK+ D L +D
Sbjct: 19138 LTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSD 19197
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
G+Y A N+ G+ A + V D P + V+V S
Sbjct: 19198 GGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSS 19237
Score = 37.9 bits (84), Expect = 0.22
Identities = 94/410 (22%), Positives = 146/410 (35%), Gaps = 45/410 (10%)
Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV---LDDGSLRLDNVILADEGEY 270
Q G + + + G P P + W + G R+ V LD +L + D G+Y
Sbjct: 24169 QVGQDLKIEVPISGRPKPTITWTKD-GLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQY 24227
Query: 271 SCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
N VG +AS + D P P V+ +V+ + T + P P +
Sbjct: 24228 GITVANVVGQKTASIEIVTLDKPDPPKGP----VKFDDVSAESITLSWNP-PLYTGGCQI 24282
Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
I+ RD T V+D V+ T K T + +
Sbjct: 24283 TNYIV---QKRDT--TTTVWDVVSATVARTTLKVTKLKTGTEYQFRIFAENRYGQSFALE 24337
Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE----GEALIQNHRRNV 446
SD PI+ P + P + TAI +I W+ G +I H
Sbjct: 24338 SD-----PIVAQYPYKEPGPPGTPFA---TAISKDSMVIQWHEPVNNGGSPVIGYHLERK 24389
Query: 447 TNDGTLVLKDLDKSDSGTYTCVASSRHG-KY---VWSGALLVDSPINPNIHFFRAADVSS 502
+ L K T + G +Y V++ ++ + N + A D
Sbjct: 24390 ERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD 24449
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
PG P +PI V +TL W++ G S I GY VE R+ G W+
Sbjct: 24450 PPGTP-EPIM--VKRNEITLQWTKPVYDGGSMITGYIVE--KRDLPDGR--------WMK 24496
Query: 563 IA-RRVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
+ V +T + V L Y F V +N+ G +S PS + +T D+
Sbjct: 24497 ASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDE 24546
Score = 37.9 bits (84), Expect = 0.22
Identities = 40/185 (21%), Positives = 70/185 (37%), Gaps = 22/185 (11%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
P P + W + +N+ +D +++ D S T V + GKY+ + V
Sbjct: 28226 PPPTVTW--------RKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGV 28277
Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
P + + + V P K +V+ +VTL W G S I+ Y +E
Sbjct: 28278 GEPKSSTV----SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIE--K 28331
Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDS 604
R+ R W V++ + T + + L + F V EN G+ P ++
Sbjct: 28332 RDA--------TKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEP 28383
Query: 605 VTVGD 609
V +
Sbjct: 28384 VKAAE 28388
Score = 37.9 bits (84), Expect = 0.22
Identities = 31/120 (25%), Positives = 51/120 (42%), Gaps = 12/120 (10%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P PP + + + +S L+W + + G S I GY +E+ + S WV
Sbjct: 29473 PAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEM----------RQKGSDFWVE- 29521
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDS-NSLWEGTGVSN 622
A Q + V+ L+ Y F V+ +N G S P SV + + + TG++N
Sbjct: 29522 AGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITN 29581
Score = 37.5 bits (83), Expect = 0.29
Identities = 28/117 (23%), Positives = 50/117 (42%), Gaps = 10/117 (8%)
Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---- 255
IK L + + + G V V G P+P + W ++ P +++ +
Sbjct: 16324 IKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRS 16383
Query: 256 ----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306
L + + D+G Y+ A N +G+V + ++ VYD PS NL+ + ES
Sbjct: 16384 EAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAES 16440
Score = 37.5 bits (83), Expect = 0.29
Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 5/127 (3%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
F+ T L + +YEF + GKPS D P PP E I+ +V L+
Sbjct: 23327 FKTTGLEEGVEYEFRVSAENIVGIGKPSKVSECYVARD-PCDPPGRPEAIIVTRNSVTLQ 23385
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
W P ITGY +V ++P + M A T + T +T L Y ++
Sbjct: 23386 WKKPTYD-GGSKITGY--IVEKKELPEGRWMKASFTNIID-THFEVTGLVEDHRYEFRVI 23441
Query: 812 AETIIGL 818
A G+
Sbjct: 23442 ARNAAGV 23448
Score = 37.5 bits (83), Expect = 0.29
Identities = 32/105 (30%), Positives = 45/105 (42%), Gaps = 10/105 (9%)
Query: 506 PPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR 565
PP +++ SV+LSW Q G S I GY VE R+ G T +
Sbjct: 27697 PPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRWTKAS-------FT 27747
Query: 566 RVHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGD 609
V +T +++ L Y F V N+ G +S PS V +T D
Sbjct: 27748 NVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCID 27792
Score = 37.5 bits (83), Expect = 0.29
Identities = 30/106 (28%), Positives = 45/106 (42%), Gaps = 9/106 (8%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PGPPT + + T+V+L WS+ G I+GY +E+ + G+ N+ V
Sbjct: 29181 PGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADL--GDWHKVNAEACV-- 29236
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+T Y V L G Y F V N G V+ ++ D
Sbjct: 29237 -----KTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVD 29277
Score = 37.1 bits (82), Expect = 0.38
Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 2/89 (2%)
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRES 191
RG P P W +G + D + + + L I++ + D G YQ NAAG++
Sbjct: 18462 RGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTV 18521
Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVT 220
A+ + + P TGP +++ T +T
Sbjct: 18522 AVHLTVLDV-PGPPTGPINILDVTPEHMT 18549
Score = 37.1 bits (82), Expect = 0.38
Identities = 30/110 (27%), Positives = 41/110 (37%), Gaps = 11/110 (10%)
Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRG 559
VS P PP + +VT + T+ W + G S I GY VE+ + S
Sbjct: 26219 VSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEM----------QTKGSEK 26268
Query: 560 WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
W +V + L G Y+F V N G S P + V D
Sbjct: 26269 WST-CTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARD 26317
Score = 36.7 bits (81), Expect = 0.50
Identities = 16/52 (30%), Positives = 26/52 (50%), Gaps = 2/52 (3%)
Query: 1 MSDDYVTSGE--APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV 50
++++ GE APY I +P+ + C+ GG+P P + W K GV
Sbjct: 1069 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGV 1120
Score = 36.7 bits (81), Expect = 0.50
Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 10/124 (8%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVI 167
F E + + GD L + G P+P + W NG L D + + DG + L+I
Sbjct: 3505 FIKEVSNADISMGDVATLS-VTVIGIPKPKIQWFFNGVLLTPSADYKF-VFDGDDHSLII 3562
Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG 227
+ D G Y C+A N G + A LKI+ K G +D +T S+V G
Sbjct: 3563 LFTKLEDEGEYTCMASNDYG-KTICSAYLKINSKG---EGHKD--TETESAVAKSLEKLG 3616
Query: 228 DPLP 231
P P
Sbjct: 3617 GPCP 3620
Score = 36.7 bits (81), Expect = 0.50
Identities = 25/83 (30%), Positives = 38/83 (45%), Gaps = 2/83 (2%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
G P P + W K+G+ L + + D NLV +D+ + D+G Y A N G +
Sbjct: 22414 GRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKH- 22472
Query: 193 IATLKIHIKPYLITGPEDVVAQT 215
I +K+ +P GP V T
Sbjct: 22473 IFNVKVLDRPGPPEGPLAVTEVT 22495
Score = 36.7 bits (81), Expect = 0.50
Identities = 30/103 (29%), Positives = 49/103 (47%), Gaps = 9/103 (8%)
Query: 719 SNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPA 778
S VAQ VP GPP + + + ++ ++W+ P + +G G V+ L+
Sbjct: 23256 SEPTVAQYPFKVP-GPPGTPVVTLSSRDSMEVQWNEP---ISDG---GSRVIGYHLERKE 23308
Query: 779 NKSM--VAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
S+ V +N T T T L GV Y +++AE I+G+G
Sbjct: 23309 RNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIG 23351
Score = 36.7 bits (81), Expect = 0.50
Identities = 20/62 (32%), Positives = 36/62 (58%), Gaps = 5/62 (8%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186
+P +G P+ V W+K+GQTL +R+++ +L I++A + D G Y+ N+A
Sbjct: 26343 VPFKGRPQATVNWRKDGQTL--KETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSA 26400
Query: 187 GT 188
G+
Sbjct: 26401 GS 26402
Score = 36.7 bits (81), Expect = 0.50
Identities = 33/123 (26%), Positives = 53/123 (43%), Gaps = 6/123 (4%)
Query: 702 KYEFFLIPFYKKFEGKPSNSR--VAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQL 759
+Y+F + K G+P +S VAQ VPD P I E + ++ L W+ PE
Sbjct: 29048 EYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIP-EPSNITGNSITLTWARPE--- 29103
Query: 760 QNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
+G ++ + + + + I+ T +T LT G Y + AE G+G
Sbjct: 29104 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 29163
Query: 820 PFS 822
P S
Sbjct: 29164 PAS 29166
Score = 36.3 bits (80), Expect = 0.67
Identities = 34/126 (26%), Positives = 51/126 (40%), Gaps = 10/126 (7%)
Query: 177 RYQCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQ---TGSSVTFQCRVGGD 228
+++ +A NAAG + A + +K P LI Q G ++ + G
Sbjct: 18113 KFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGV 18172
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P P V W++ R+ V GS L + N D G YS EN G+ + S +
Sbjct: 18173 PFPKVTWKKEDRDAPTK-ARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKV 18231
Query: 288 TVYDPP 293
V D P
Sbjct: 18232 LVLDKP 18237
Score = 36.3 bits (80), Expect = 0.67
Identities = 28/89 (31%), Positives = 42/89 (47%), Gaps = 5/89 (5%)
Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
GPP ++E+ + + +L W P L +IT Y VV DV A+ ++ T +
Sbjct: 18238 GPPRDLEVSEIRKDSCYLTWKEP-LDDGGSVITNY--VVERRDV-ASAQWSPLSAT-SKK 18292
Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGPF 821
S +L G Y ++AAE G GPF
Sbjct: 18293 KSHFAKHLNEGNQYLFRVAAENQYGRGPF 18321
Score = 36.3 bits (80), Expect = 0.67
Identities = 22/68 (32%), Positives = 39/68 (57%), Gaps = 6/68 (8%)
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAG-T 188
+G PEP++ W K G+ L+ + R+ L+ L I++A + D G+Y A+N++G
Sbjct: 18860 KGRPEPDITWTKEGKVLV--REKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHA 18917
Query: 189 RESAIATL 196
+ SAI +
Sbjct: 18918 QGSAIVNV 18925
Score = 36.3 bits (80), Expect = 0.67
Identities = 28/91 (30%), Positives = 44/91 (48%), Gaps = 6/91 (6%)
Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
D P GPP ++++ + T+V L W PP L +G N +V + K+ + T
Sbjct: 22877 DTP-GPPQDLKVKEVTKTSVTLTWDPP---LLDGGSKIKNYIVEKRE-STRKAYSTVATN 22931
Query: 789 VHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
H+ TS + L G SY ++ AE G+G
Sbjct: 22932 CHK-TSWKVDQLQEGCSYYFRVLAENEYGIG 22961
Score = 36.3 bits (80), Expect = 0.67
Identities = 27/99 (27%), Positives = 44/99 (44%), Gaps = 4/99 (4%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
++ + G+S T G P+P+VLW + V D SL ++N D G+
Sbjct: 27123 LIVKAGASFTMTVPFRGRPVPNVLWSK-PDTDLRTRAYVDTTDSRTSLTIENANRNDSGK 27181
Query: 270 YSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVES 306
Y+ +N + A S + + V D P N++ V ES
Sbjct: 27182 YTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKES 27220
Score = 35.9 bits (79), Expect = 0.88
Identities = 28/102 (27%), Positives = 42/102 (41%), Gaps = 4/102 (3%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+ P I+ P V V + A CR G P P + WY G L + + R + G+ +L
Sbjct: 1839 QKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQL-IRKSKRFRVRYDGIHYL 1897
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
+ + D G A N G + L + RE+FR
Sbjct: 1898 DIVDCKSY-DTGEVKVTAENPEGVIEHK-VKLEIQ-QREDFR 1936
Score = 35.9 bits (79), Expect = 0.88
Identities = 24/82 (29%), Positives = 33/82 (40%), Gaps = 1/82 (1%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
L PE + +G+T C G P+P V W NGQ + R+ L I D +
Sbjct: 1845 LYPEPVRVLEGETARFRCRVT-GYPQPKVNWYLNGQLIRKSKRFRVRYDGIHYLDIVDCK 1903
Query: 172 QTDAGRYQCIARNAAGTRESAI 193
D G + A N G E +
Sbjct: 1904 SYDTGEVKVTAENPEGVIEHKV 1925
Score = 35.9 bits (79), Expect = 0.88
Identities = 33/132 (25%), Positives = 57/132 (43%), Gaps = 8/132 (6%)
Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV---PDGPPINIEMFILNTT 746
+ F +T+L +Y F + + G P++ D PD PP +E+ +
Sbjct: 19682 TSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPD-PPRKLEVTEMTKN 19740
Query: 747 TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSY 806
+ L W PP L+ I GY + PA++ +V + SL++T L G Y
Sbjct: 19741 SATLAWLPP-LRDGGAKIDGYITSYREEEQPADRWT---EYSVVKDLSLVVTGLKEGKKY 19796
Query: 807 SVQIAAETIIGL 818
++AA +G+
Sbjct: 19797 KFRVAARNAVGV 19808
Score = 35.9 bits (79), Expect = 0.88
Identities = 23/82 (28%), Positives = 33/82 (40%), Gaps = 1/82 (1%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I P +T+ + + G P P +W KG VV+ +H ++ A L
Sbjct: 19826 PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSIL-I 19884
Query: 72 THGRVHSDAGVYWCEATNSYGT 93
D+G Y A NS GT
Sbjct: 19885 IKDVTRKDSGYYSLTAENSSGT 19906
Score = 35.9 bits (79), Expect = 0.88
Identities = 30/94 (31%), Positives = 42/94 (44%), Gaps = 6/94 (6%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+P G P P V W K+ L + +L+ I+DA + D G Y N+AG
Sbjct: 23096 VPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG- 23154
Query: 189 RESAIATLKIHI--KPYLITGPEDVVAQTGSSVT 220
AI TL + + KP TGP + T S+T
Sbjct: 23155 --EAIETLNVIVLDKPGPPTGPVKMDEVTADSIT 23186
Score = 35.9 bits (79), Expect = 0.88
Identities = 35/144 (24%), Positives = 51/144 (35%), Gaps = 10/144 (6%)
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED--------VVAQTGS 217
V+ R+ ++ A N AG + L + IK L D V + GS
Sbjct: 27360 VVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSHTVYVRAGS 27419
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275
++ + G PLP V R M ++ ++ L + AD G Y A
Sbjct: 27420 NLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAA 27479
Query: 276 NSVGAVSASGYLTVYDPPSINLSP 299
NS G A + V D P P
Sbjct: 27480 NSSGTTKAFINIVVLDRPGPPTGP 27503
Score = 35.5 bits (78), Expect = 1.2
Identities = 26/80 (32%), Positives = 38/80 (47%), Gaps = 5/80 (6%)
Query: 411 IKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDG--TLVLKDLDKSDSGTY 465
++ M V F C P P IAWY +G+ + R + DG +L + + D G Y
Sbjct: 1303 LEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGIY 1362
Query: 466 TCVASSRHGKYVWSGALLVD 485
T AS+ G + SG L V+
Sbjct: 1363 TAFASNIKGNAICSGKLYVE 1382
Score = 35.1 bits (77), Expect = 1.5
Identities = 59/230 (25%), Positives = 85/230 (36%), Gaps = 32/230 (13%)
Query: 374 AVNYAGSSFVRG--KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC--TPEPII 429
AVN AG S + + D PP +I + + IK +AI P P +
Sbjct: 18118 AVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKV 18177
Query: 430 AWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPI 488
W E R +VT G+ L +++ D G Y+ + G S +LV
Sbjct: 18178 TWKKEDRDAPTKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLV---- 18233
Query: 489 NPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548
PGPP + S L+W + G S I Y VE R+
Sbjct: 18234 ------------LDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE--RRDVA 18279
Query: 549 SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
S +P + A ++H+ K L G Y+F V EN +G GP
Sbjct: 18280 SAQWSP-------LSATSKKKSHF-AKHLNEGNQYLFRVAAENQYG-RGP 18320
Score = 35.1 bits (77), Expect = 1.5
Identities = 32/105 (30%), Positives = 50/105 (47%), Gaps = 7/105 (6%)
Query: 507 PTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARR 566
P +P +VT ++V+L WS G S ++GY +E R+ +S R + I
Sbjct: 29869 PGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIE---RKPVSEVGDGRWLKCNYTI--- 29922
Query: 567 VHQTHYVVKSLIPGITYMFIVRTENSHG-LSGPSPVSDSVTVGDD 610
V + V +L G TY F V +N+ G +S S + VT D+
Sbjct: 29923 VSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDE 29967
Score = 34.7 bits (76), Expect = 2.0
Identities = 20/68 (29%), Positives = 33/68 (48%), Gaps = 4/68 (5%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTL--DDV-PDGPPINIEMFILNTTTV 748
F + L +Y FF + +F P + +T D + P PPI +++ ++ TV
Sbjct: 16897 FVVPDLLSEQQY-FFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTV 16955
Query: 749 HLKWSPPE 756
HL W PP+
Sbjct: 16956 HLSWKPPK 16963
Score = 34.7 bits (76), Expect = 2.0
Identities = 24/71 (33%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRES 191
G P P V WKK+G TLL + + L + + D+G Y A N++G++ S
Sbjct: 20248 GKPMPTVSWKKDG-TLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSK-S 20305
Query: 192 AIATLKIHIKP 202
A LK+ KP
Sbjct: 20306 ATIKLKVLDKP 20316
Score = 34.7 bits (76), Expect = 2.0
Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 4/103 (3%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLD-DGSLRLDNVILADEG 268
++ + G ++ V G P P + W + +G +K D D LR +NV D G
Sbjct: 20630 LILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAG 20689
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPS--INLSPNSVNVESGNV 309
+Y ENS G + + V D P +N++ ++ +S V
Sbjct: 20690 KYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYV 20732
Score = 34.7 bits (76), Expect = 2.0
Identities = 34/137 (24%), Positives = 57/137 (41%), Gaps = 5/137 (3%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV-PDGPPINIEMFILNTTTVHL 750
+++T L +Y F ++ K G+P S + P GPP E+ + ++ +
Sbjct: 25788 YKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVV 25847
Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
W+ P + I GY ++ D + N L +T LT G SY ++
Sbjct: 25848 TWARP-VDDGGTEIEGY--ILEKRDKEGVR-WTKCNKKTLTDLRLRVTGLTEGHSYEFRV 25903
Query: 811 AAETIIGLGPFSQKVYF 827
AAE G+G S+ F
Sbjct: 25904 AAENAAGVGEPSEPSVF 25920
Score = 34.3 bits (75), Expect = 2.7
Identities = 45/206 (21%), Positives = 80/206 (38%), Gaps = 19/206 (9%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD---GSL 257
KP + D++ G ++ P+P V W + G R+ + +D L
Sbjct: 15313 KPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKD-GKEVKASDRLTMKNDHISAHL 15371
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ + AD G Y+ EN +G+ +AS + V I L ++++ ++ + +C T
Sbjct: 15372 EVPKSVRADAGIYTITLENKLGSATASINVKV-----IGLPGPCKDIKASDITKSSCKLT 15426
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSR---DKYHATAVFDGVTVL--TINDTDKNDSRNTIVC 372
EP F +G I+ + R + V G L T+ D N V
Sbjct: 15427 W--EPPEF---DGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 15481
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPP 398
+ G ++ K V + D + PP
Sbjct: 15482 AVNKVGGGEYIELKNPVIAQDPKQPP 15507
Score = 34.3 bits (75), Expect = 2.7
Identities = 25/93 (26%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSC 272
G ++ V G P+P +W + G + RV + + G+ L + + + D G Y
Sbjct: 16046 GKTLRIPAVVTGRPVPTKVWTKEEG--ELDKDRVVIDNVGTKSELIIKDALRKDHGRYVI 16103
Query: 273 EAENSVGAVSASGYLTVYDPPS--INLSPNSVN 303
A NS G+ A+ + V+D P ++L P N
Sbjct: 16104 TATNSCGSKFAAARVEVFDVPGPVLDLKPVVTN 16136
Score = 34.3 bits (75), Expect = 2.7
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 4/76 (5%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQC 180
GDT+ L + +G P P V WKK + +R+ + G L I++A D G Y
Sbjct: 18160 GDTLRLSAII-KGVPFPKVTWKKEDRDA--PTKARIDVTPVGSKLEIRNAAHEDGGIYSL 18216
Query: 181 IARNAAGTRESAIATL 196
N AG++ ++ L
Sbjct: 18217 TVENPAGSKTVSVKVL 18232
Score = 34.3 bits (75), Expect = 2.7
Identities = 23/84 (27%), Positives = 35/84 (41%), Gaps = 1/84 (1%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
V+ + G + V G P P V WR+ + G+V ++D L + N D G+
Sbjct: 19543 VIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGK 19602
Query: 270 YSCEAENSVGAVSASGYLTVYDPP 293
YS N G + + V D P
Sbjct: 19603 YSLTLVNPAGEKAVFVNVRVLDTP 19626
Score = 34.3 bits (75), Expect = 2.7
Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 5/130 (3%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPS-NSRVAQTLDDV-PDGPPINIEMFILNTTTVH 749
++++ L + +YEF ++ PS S + D V GPP N + + +++
Sbjct: 22641 YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSIS 22700
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
+ W+ P + ITGY V + + ++ + +ATS +T LT Y ++
Sbjct: 22701 IAWNKP-IYDGGSEITGYMVEIALPE--EDEWQIVTPPAGLKATSYTITGLTENQEYKIR 22757
Query: 810 IAAETIIGLG 819
I A GLG
Sbjct: 22758 IYAMNSEGLG 22767
Score = 34.3 bits (75), Expect = 2.7
Identities = 34/128 (26%), Positives = 56/128 (43%), Gaps = 7/128 (5%)
Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDD--VPDGPPINIEMFILNTTTVHL 750
++T L K +Y F + K G+P S + LD VP PP ++E+ + ++ L
Sbjct: 26870 KVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPS-PPTSLEITSVTKESMTL 26928
Query: 751 KWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQI 810
WS PE I+GY ++ + + + V +N + T L G Y ++
Sbjct: 26929 CWSRPESD-GGSEISGY--IIERREKNSLR-WVRVNKKPVYDLRVKSTGLREGCEYEYRV 26984
Query: 811 AAETIIGL 818
AE GL
Sbjct: 26985 YAENAAGL 26992
Score = 34.3 bits (75), Expect = 2.7
Identities = 22/65 (33%), Positives = 33/65 (50%), Gaps = 2/65 (3%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQC 180
G V LE LP +G P+P++ W K+G L R + L I++A++ G+Y
Sbjct: 28505 GHNVHLE-LPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTV 28563
Query: 181 IARNA 185
I NA
Sbjct: 28564 ILDNA 28568
Score = 33.9 bits (74), Expect = 3.6
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 4/94 (4%)
Query: 385 GKLT-VTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
G LT VT+D ++ P I P + A F C P+P + WY G+ + ++
Sbjct: 1826 GALTGVTTDQKEKQKPDIVLYPEPVRVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSK 1885
Query: 443 RRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHG 474
R V DG L + D D+G A + G
Sbjct: 1886 RFRVRYDGIHYLDIVDCKSYDTGEVKVTAENPEG 1919
Score = 33.9 bits (74), Expect = 3.6
Identities = 47/188 (25%), Positives = 72/188 (38%), Gaps = 20/188 (10%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESA 192
G PEP + W K L D + V + V I D++++D G Y A N G R +A
Sbjct: 14643 GKPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG-RATA 14701
Query: 193 IATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRV----GGDPLPDVLWRRSAGGGNMP 245
+ + + KP GP D+ T S GG + + + R A +
Sbjct: 14702 VVEVNVLDKP----GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVW 14757
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVY--DPPS--INLS 298
+ D + + +I E + AEN G V AS Y DPP L
Sbjct: 14758 HKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE 14817
Query: 299 PNSVNVES 306
P+ + ++
Sbjct: 14818 PSDITKDA 14825
Score = 33.9 bits (74), Expect = 3.6
Identities = 29/104 (27%), Positives = 44/104 (42%), Gaps = 8/104 (7%)
Query: 718 PSNSRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
PS+ + A D + P GPPI + ++TT+ L+W PP G I GY V +
Sbjct: 15917 PSDPKTAH--DPISPPGPPIP-RVTDTSSTTIELEWEPPAFN-GGGEIVGYFVDKQLVGT 15972
Query: 777 PANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGP 820
V Q T + + G Y ++++A G GP
Sbjct: 15973 NEWSRCTEKMIKVRQYT---VKEIREGADYKLRVSAVNAAGEGP 16013
Score = 33.9 bits (74), Expect = 3.6
Identities = 25/95 (26%), Positives = 42/95 (44%), Gaps = 3/95 (3%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQC 180
G+T LE G P P + W + + + + D L+++DA + D G+Y
Sbjct: 24567 GETFRLEA-DVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQYIL 24625
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT 215
A N AG++ + +K+ +P GP V T
Sbjct: 24626 RASNVAGSKSFPV-NVKVLDRPGPPEGPVQVTGVT 24659
Score = 33.9 bits (74), Expect = 3.6
Identities = 32/128 (25%), Positives = 52/128 (40%), Gaps = 5/128 (3%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVA-QTLDDV-PDGPPINIEMFILNTTTVHLK 751
+T L + +YEF + G+PS + V + D V GPP N + ++ L
Sbjct: 24807 VTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLA 24866
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
W P + I GY VV + + T + T ++ LT Y +++
Sbjct: 24867 WGKP-IYDGGSEILGY--VVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVC 24923
Query: 812 AETIIGLG 819
A +GLG
Sbjct: 24924 ALNKVGLG 24931
Score = 33.9 bits (74), Expect = 3.6
Identities = 37/138 (26%), Positives = 59/138 (42%), Gaps = 14/138 (10%)
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE-DV--------VAQTGS 217
+ D + + +++ A N AG +S T I L T PE D+ V + G+
Sbjct: 29242 VTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDRL-TAPELDIDANFKQTHVVRAGA 29300
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGS-LRLDNVILADEGEYSCEAE 275
S+ G P P +W S N+ L + D S L ++N D G+Y+ E
Sbjct: 29301 SIRLFIAYQGRPTPTAVW--SKPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVE 29358
Query: 276 NSVGAVSASGYLTVYDPP 293
N+ G+ S + + V D P
Sbjct: 29359 NNSGSKSITFTVKVLDTP 29376
Score = 33.5 bits (73), Expect = 4.7
Identities = 27/114 (23%), Positives = 45/114 (39%), Gaps = 7/114 (6%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADE 267
+V + G + + G PLP + W + G R +++ + L + + I D
Sbjct: 26726 IVVKAGEVLKINADIAGRPLPVISWAKD-GIEIEERARTEIISTDNHTLLTVKDCIRRDT 26784
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
G+Y +N G S + V D P P +N G A + GRP+
Sbjct: 26785 GQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEIN---GLTAEKCSLSWGRPQ 26835
Score = 33.1 bits (72), Expect = 6.2
Identities = 27/89 (30%), Positives = 37/89 (41%), Gaps = 4/89 (4%)
Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
P GPP +E + V L W P+ ITGY V LD P V N
Sbjct: 14809 PPGPPTRLEPSDITKDAVTLTWCEPD-DDGGSPITGY--WVERLD-PDTDKWVRCNKMPV 14864
Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLG 819
+ T+ + LT+ Y ++ AE + G G
Sbjct: 14865 KDTTYRVKGLTNKKKYRFRVLAENLAGPG 14893
Score = 33.1 bits (72), Expect = 6.2
Identities = 32/131 (24%), Positives = 56/131 (42%), Gaps = 7/131 (5%)
Query: 682 TILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMF 741
TI ++ + F I +L++ Y F ++ + G P+ + + + P PP + +
Sbjct: 26174 TITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSE-PPLPPGRVTLV 26232
Query: 742 ILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLT 801
+ T +KW PE ITGY VV + K +AT ++ LT
Sbjct: 26233 DVTRNTATIKWEKPESD-GGSKITGY--VVEMQTKGSEKWSTCTQVKTLEAT---ISGLT 26286
Query: 802 SGVSYSVQIAA 812
+G Y ++AA
Sbjct: 26287 AGEEYVFRVAA 26297
Score = 33.1 bits (72), Expect = 6.2
Identities = 29/102 (28%), Positives = 41/102 (40%), Gaps = 3/102 (2%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDDGS-LRLDNVILADEG 268
V+A+ G V G P P V WR+ G+ ++ D S L + V D G
Sbjct: 28208 VIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG 28267
Query: 269 EYSCEAENSVGAVSASGY-LTVYDPPSINLSPNSVNVESGNV 309
+Y EN VG +S + V D P+ +V G V
Sbjct: 28268 KYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTV 28309
Score = 33.1 bits (72), Expect = 6.2
Identities = 37/150 (24%), Positives = 61/150 (40%), Gaps = 19/150 (12%)
Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN---VESGNV 309
++ R+ + A +G+ SCE ++ AV LT P +++ N V +G
Sbjct: 29249 EEYKFRVSAINGAGKGD-SCEVTGTIKAVDR---LTA---PELDIDANFKQTHVVRAGAS 29301
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
R GRP PT WS + + R H T D + LT+ + ++ND+
Sbjct: 29302 IRLFIAYQGRPTPTAVWSKPDSNLSL-----RADIHTT---DSFSTLTVENCNRNDA-GK 29352
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
+ N +GS + + V P PI
Sbjct: 29353 YTLTVENNSGSKSITFTVKVLDTPGPPGPI 29382
Score = 32.7 bits (71), Expect = 8.2
Identities = 31/104 (29%), Positives = 44/104 (42%), Gaps = 10/104 (9%)
Query: 37 GSPSPAIRWYKGGVL-------VVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
G P P + W+K V+ DTH + L L R SD G+Y A N
Sbjct: 17069 GVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSR-RSDTGLYTITAVN 17127
Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
+ GTA S+ L+V + R + P +S D + L PP+
Sbjct: 17128 NLGTA-SKEMRLNV-LGRPGPPVGPIKFESVSADQMTLSWFPPK 17169
Score = 32.7 bits (71), Expect = 8.2
Identities = 30/113 (26%), Positives = 42/113 (37%), Gaps = 5/113 (4%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+T+ + L R G P P + W+K V+ D I L + SD+
Sbjct: 17755 LTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAK-RSDS 17813
Query: 81 GVYWCEATNSYGTARSRNATLHVAVL-REEFRLEPESKQSAQGDTVVLECLPP 132
G Y NS G SR V V+ R + P S D +V+ PP
Sbjct: 17814 GKYCVVVENSTG---SRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPP 17863
Score = 32.7 bits (71), Expect = 8.2
Identities = 34/124 (27%), Positives = 49/124 (39%), Gaps = 7/124 (5%)
Query: 702 KYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQN 761
+Y F + K PS T +P PP E+ + +TV L W+ P+ +
Sbjct: 20088 EYSFRIYALNKAGSSPPSKPTEYVTAR-MPVDPPGKPEVIDVTKSTVSLIWARPKHDGGS 20146
Query: 762 GIITGYNVVVNWLDVPANKSMVAINTTVHQ--ATSLIMTNLTSGVSYSVQIAAETIIGLG 819
II GY V +P +K V NT HQ T L Y + A T + +
Sbjct: 20147 KII-GY--FVEACKLPGDK-WVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNIS 20202
Query: 820 PFSQ 823
P S+
Sbjct: 20203 PPSE 20206
Score = 32.7 bits (71), Expect = 8.2
Identities = 22/69 (31%), Positives = 28/69 (40%)
Query: 225 VGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS 284
+ G P P+V W R G L + NV D G+Y ENS G+ SA
Sbjct: 22811 IKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAF 22870
Query: 285 GYLTVYDPP 293
+ V D P
Sbjct: 22871 VNVRVLDTP 22879
Score = 32.7 bits (71), Expect = 8.2
Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 6/91 (6%)
Query: 729 DVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTT 788
D P GPP N+ + + + L W PP + +G N V++ + K+ +++
Sbjct: 25041 DTP-GPPQNLAVKEVRKDSAFLVWEPPII---DGGAKVKNYVIDKRE-STRKAYANVSSK 25095
Query: 789 VHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
+ TS + NLT G Y ++ AE G+G
Sbjct: 25096 CSK-TSFKVENLTEGAIYYFRVMAENEFGVG 25125
Score = 32.7 bits (71), Expect = 8.2
Identities = 30/97 (30%), Positives = 36/97 (37%), Gaps = 5/97 (5%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P P I W K G + T ++ L G D G Y ATNS GTA
Sbjct: 25264 GRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGN-KDDFGKYTVTATNSAGTA-- 25320
Query: 97 RNATLHVAVLREEF-RLEPESKQSAQGDTVVLECLPP 132
L V VL + + P D VV+ PP
Sbjct: 25321 -TENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPP 25356
>X90569-1|CAA62189.1| 7962|Homo sapiens elastic titin protein.
Length = 7962
Score = 141 bits (341), Expect = 2e-32
Identities = 138/492 (28%), Positives = 198/492 (40%), Gaps = 32/492 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E PY IE V +PATL C+ G+P I WYK + S + + L
Sbjct: 3683 EPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLRSAPAYKMQFKNNVASL 3742
Query: 70 RATHGRVHSDAGVYWCEATNSYGT-ARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
+ HSD G Y C+A NS G A S + L F + + G V E
Sbjct: 3743 -VINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARKLKDVHETLGFPVAFE 3801
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
C GS V W K+G L D + + V L I Q+ G+Y C A N G
Sbjct: 3802 CRI-NGSEPLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLG 3860
Query: 188 TRES-AIATLKIH-IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241
T S A L H + P+ P V G S TF+C V G + W R G
Sbjct: 3861 TASSSAKLILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNREIRPG 3920
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSP 299
GN + V+ + +L + V D G+Y+C A N G S S L V +PP L P
Sbjct: 3921 GNYKMTLVE--NTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFIKKLEP 3978
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ + V+ R+ C G PE + W + K+ + V D V VL ++
Sbjct: 3979 SRI-VKQDEFTRYECKIGGSPEIKVLWYKDETEI-----QESSKFRMSFV-DSVAVLEMH 4031
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FP 418
+ DS C A N AGS+ L V + PPI P + +K V
Sbjct: 4032 NLSVEDS-GDYTCEAHNAAGSASSSTSLKV-----KEPPIFRKKP-HPIETLKGADVHLE 4084
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLV---LKDLDKSDSGTYTCVASSRHGK 475
C TP ++WY + L + + ++ L + ++D +D G Y C A++ G
Sbjct: 4085 CELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS 4144
Query: 476 YVWSGALLVDSP 487
G++ + +P
Sbjct: 4145 DTCVGSIALKAP 4156
Score = 138 bits (334), Expect = 1e-31
Identities = 117/463 (25%), Positives = 193/463 (41%), Gaps = 23/463 (4%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C+ GGSP + WYK + + + + L H D+G Y CEA N+ G
Sbjct: 3992 CKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEM-HNLSVEDSGDYTCEAHNAAG 4050
Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
+A S + +L V FR +P ++ +G V LEC +G+P +V W K+ + L
Sbjct: 4051 SASS-STSLKVKE-PPIFRKKPHPIETLKGADVHLEC-ELQGTPPFHVSWYKDKRELR-S 4106
Query: 153 GDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
G + + ++ I + D G YQC A N G+ ++ + ++ + P + D
Sbjct: 4107 GKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGS-DTCVGSIALKAPPRFVKKLSD 4165
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL---DDGSLRLDNVILADE 267
+ G V Q + G V+W + G + + + +L+ V A+
Sbjct: 4166 ISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANA 4225
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
G+Y+C+ +N G L+V +P +I P S+ V +G+ CT G PE + W
Sbjct: 4226 GKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWF 4285
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
+G ++ D + + F+ V+ L I + +DS N G L
Sbjct: 4286 KDGKE------LTSDNKYKISFFNKVSGLKIINVAPSDS-GVYSFEVQNPVGKDSCTASL 4338
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
V+ D PP T S V C +P ++W+ EG + + T
Sbjct: 4339 QVS--DRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTT 4396
Query: 448 ---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
N L + L++SDSG YTC+A++ G S L V P
Sbjct: 4397 LTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREP 4439
Score = 138 bits (334), Expect = 1e-31
Identities = 135/536 (25%), Positives = 220/536 (41%), Gaps = 30/536 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T E P +++P + V T G+P ++ W+KG +V ++
Sbjct: 4434 LTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDS 4493
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLEPESKQSAQGDT 124
+ L S +G Y C +N G A + T H+ + +F +G
Sbjct: 4494 VAELELFDVDT-SQSGEYTCIVSNEAGKA---SCTTHLYIKAPAKFVKRLNDYSIEKGKP 4549
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
++LE G+P +V WKKNG + + + ++ I + DAG+Y C
Sbjct: 4550 LILEG-TFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIE 4608
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
NA+G ++S A + I PY + E V G S + QC++ G P V W + G
Sbjct: 4609 NASG-KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYK--GDTK 4665
Query: 244 M-PLGRVKV---LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSIN 296
+ P K+ + +L + V + D GEY C+AENSVG VSAS +LTV + PPS +
Sbjct: 4666 LRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFS 4725
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
V G F C +G ++ W +G P + T+ D L
Sbjct: 4726 RQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQ------TSFLDNTATL 4779
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
I TD++ C+A N GS+ +L +T + + PP + + A
Sbjct: 4780 NIFKTDRS-LAGQYSCTATNPIGSASSSARLILT--EGKNPPFFDIRLAPVDAVVGESAD 4836
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRH 473
F C T ++W + + + ++ N L + +DK DSG YTC A +
Sbjct: 4837 FECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEV 4896
Query: 474 GKYVWSGALLVDSPINPNIHFFRAAD-VSSLPGPPTKPITHNVTDTSVTLSWSQNN 528
GK + L + + P R ++ V G K +T++W +NN
Sbjct: 4897 GKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKNN 4952
Score = 136 bits (328), Expect = 6e-31
Identities = 138/532 (25%), Positives = 215/532 (40%), Gaps = 32/532 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E I+E+P + V TL C G+P + +W+K G + SD I + L
Sbjct: 4249 EPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGL 4308
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVL 127
+ + SD+GVY E N G S A+L V+ + F + + G +VV+
Sbjct: 4309 KIIN-VAPSDSGVYSFEVQNPVG-KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVM 4366
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAA 186
EC GSP +V W G + + L D L + ++D+G Y CIA N A
Sbjct: 4367 EC-KVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMA 4425
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ E + A L + P + P+ + TG++VTF V G P V W + + +P
Sbjct: 4426 GSDECS-APLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGS-SELVPG 4483
Query: 247 GRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
R V L+D L L +V + GEY+C N G S + +L + P N +
Sbjct: 4484 DRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYS 4543
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
+E G T TG P ++ W G + P + + T + +L I +
Sbjct: 4544 IEKGKPLILEGTFTGTPPISVTWKKNGIN--VTPS---QRCNITTT-EKSPILEIPSSTV 4597
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ C N +G ++ + PP + + A C
Sbjct: 4598 EDA-GQYNCYIENASGKDSCSAQILILE-----PPYFVKQLEPVKVSVGDSASLQCQLAG 4651
Query: 424 TPEPIIAWYFEGEALI------QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
TPE ++WY +G+ + + H RN N TLV +D +DSG Y C A + G+
Sbjct: 4652 TPEIGVSWY-KGDTKLRPTTTYKMHFRN--NVATLVFNQVDINDSGEYICKAENSVGEVS 4708
Query: 478 WSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
S L V P + DV G P +++SW ++ K
Sbjct: 4709 ASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGK 4760
Score = 134 bits (324), Expect = 2e-30
Identities = 132/499 (26%), Positives = 206/499 (41%), Gaps = 38/499 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V++ E PY + + + A +L C+ G+P + WYKG DT P
Sbjct: 2738 VSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKG------DTKLRPTPEYR 2791
Query: 66 LFFLR--AT--HGRVH-SDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQS 119
+F AT +V+ +D+G Y C+A NS GTA S+ + L F + + +
Sbjct: 2792 TYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQ 2851
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRY 178
G V L C GS V W ++G L + + VD L I + +G+Y
Sbjct: 2852 TVGLPVTLTCRL-NGSAPIQVCWYRDGVLLRDHENLQTSFVDNVATLKILQTDLSHSGQY 2910
Query: 179 QCIARNAAGTRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
C A N GT S+ K P+ P + G S F+C V G + W
Sbjct: 2911 SCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPMRITWS 2970
Query: 237 RS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ GGN + V + LR+ V D G+Y+C+A N VG S L+V +P
Sbjct: 2971 KDNKEIRPGGNYTITCVG--NTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEP 3028
Query: 293 PS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P + S + G + C +G PE + W N + + KY+ + + +
Sbjct: 3029 PKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWF--RNDSELHESW---KYNMSFI-N 3082
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
V +LTIN+ DS +C A N G + LTV + PP+ T PS
Sbjct: 3083 SVALLTINEASAEDS-GDYICEAHNGVGDASCSTALTV-----KAPPVFTQKPSPVGALK 3136
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN---DGTLVLKDLDKSDSGTYTCV 468
S + C TP + W + + + + + +T+ D L + +L+ SD G Y C
Sbjct: 3137 GSDVILQCEISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCK 3196
Query: 469 ASSRHGKYVWSGALLVDSP 487
A++ G S ++ P
Sbjct: 3197 ATNEVGSDTCSCSVKFKEP 3215
Score = 127 bits (306), Expect = 3e-28
Identities = 127/507 (25%), Positives = 203/507 (40%), Gaps = 24/507 (4%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
+ C+ GSP ++ W+ G + S L + SD+G Y C ATN
Sbjct: 4366 MECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCAL-TVNMLEESDSGDYTCIATNM 4424
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
G+ +A L V F +P+ G V + +G+P +V W K L+
Sbjct: 4425 AGSDEC-SAPLTVRE-PPSFVQKPDPMDVLTGTNVTFTSIV-KGTPPFSVSWFKGSSELV 4481
Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
+ L D L + D + +G Y CI N AG + S L I +
Sbjct: 4482 PGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAG-KASCTTHLYIKAPAKFVKRLN 4540
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILAD 266
D + G + + G P V W+++ G P R + L + + + D
Sbjct: 4541 DYSIEKGKPLILEGTFTGTPPISVTWKKN-GINVTPSQRCNITTTEKSPILEIPSSTVED 4599
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
G+Y+C EN+ G S S + + +PP V V G+ A C G PE + W
Sbjct: 4600 AGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSW 4659
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
+G+ T + P + K H + V L N D NDS +C A N G V
Sbjct: 4660 -YKGD-TKLRP-TTTYKMHFR---NNVATLVFNQVDINDS-GEYICKAENSVGE--VSAS 4710
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRN 445
+T + + PP + + + VF C AI EPI ++WY +G+ L +
Sbjct: 4711 TFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDC-AISGSEPISVSWYKDGKPLKDSPNVQ 4769
Query: 446 VT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSS 502
+ N TL + D+S +G Y+C A++ G S L++ NP R A V +
Sbjct: 4770 TSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDA 4829
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNK 529
+ G H + +SW+++++
Sbjct: 4830 VVGESADFECHVTGTQPIKVSWAKDSR 4856
Score = 124 bits (299), Expect = 2e-27
Identities = 129/507 (25%), Positives = 211/507 (41%), Gaps = 26/507 (5%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E IIE+P +TV P L C G+P + +W+K G + +D+ I + L
Sbjct: 3308 EPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVASL 3367
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVL 127
+ + SD G+Y E NS G + ++HV+ ++ F + + + G +VVL
Sbjct: 3368 KIPCAEM-SDKGLYSFEVKNSVGKSNC-TVSVHVSDRIVPPSFIRKLKDVNAILGASVVL 3425
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAA 186
EC GS +V W ++G ++ + + L + +D G Y C+A N A
Sbjct: 3426 ECRVS-GSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVA 3484
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G+ E + A L + P P+ V G S+TF + G P V W + + +P
Sbjct: 3485 GSDECS-AVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRE-LVPG 3542
Query: 247 GRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
+ L+D L L V + G+YSC N G+ S + +L V +P + +
Sbjct: 3543 ESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPATFVKRLADFS 3602
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
VE+G+ T TG P ++ W ++ I S+ + + + + T+L I ++
Sbjct: 3603 VETGSPIVLEATYTGTPPISVSW-IKDEYLI-----SQSERCSITMTEKSTILEILESTI 3656
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D C N AG ++V PP + I A C
Sbjct: 3657 EDYAQ-YSCLIENEAGQDICEALVSVLE-----PPYFIEPLEHVEAVIGEPATLQCKVDG 3710
Query: 424 TPEPIIAWYFEGEAL--IQNHRRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
TPE I+WY E L ++ N+ +LV+ +D SD G Y+C A + G S
Sbjct: 3711 TPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSA 3770
Query: 481 ALLVDSPINPNIHFFRAADVSSLPGPP 507
L++ + P + DV G P
Sbjct: 3771 VLVIKARKLPPFFARKLKDVHETLGFP 3797
Score = 122 bits (293), Expect = 1e-26
Identities = 124/467 (26%), Positives = 186/467 (39%), Gaps = 30/467 (6%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C GS +I+W+K + + FL + +D+G Y C ATN
Sbjct: 1359 LECIVAGSHPISIQWFKDDQEISASEKYKFSFHDNTAFLEISQLE-GTDSGTYTCSATNK 1417
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
G + H+ V + +E Q +T V G+ + W K+ + L
Sbjct: 1418 AG---HNQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKEL- 1473
Query: 151 FDGDSRMHLVD--GGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
G +R D +L + A+ TD+G Y C N GT S ATL + P I P
Sbjct: 1474 HSGAARSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSK-ATLFVKEPPQFIKKP 1532
Query: 209 EDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN-MPLGRVKVLDD-GSLRLDNVILA 265
V V + G S TF+C++ G P V W + + +D + ++ +
Sbjct: 1533 SPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVE 1592
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+ G Y CEA N G S S L V +PP+ V V + C TG P +
Sbjct: 1593 NSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVT 1652
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT--DKNDSRNTIVCSAVNYAGSSFV 383
W ++ NR I S KY T D V+V ++ T D +D+ C N GS
Sbjct: 1653 W-LKNNREI----RSSKKYTLT---DRVSVFNLHITKCDPSDT-GEYQCIVSNEGGSCSC 1703
Query: 384 RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-- 441
++ + + PP N T +KS A F T +P I W + + L ++
Sbjct: 1704 STRVAL-----KEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDN 1758
Query: 442 -HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ V + TL ++ +D SG YTC A + G LLV P
Sbjct: 1759 VYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEP 1805
Score = 121 bits (292), Expect = 1e-26
Identities = 125/497 (25%), Positives = 190/497 (38%), Gaps = 29/497 (5%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T E PY +E+P V + L GG+ I+W+K + S RS+
Sbjct: 1426 HLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAARSVWKDD 1485
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L + +D+G Y C+ +N GTA S+ ATL V + + G +
Sbjct: 1486 TSTSLELFAAKA-TDSGTYICQLSNDVGTATSK-ATLFVKEPPQFIKKPSPVLVLRNGQS 1543
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIAR 183
EC G+P+ V W +G + + +DG I AR ++G Y C AR
Sbjct: 1544 TTFEC-QITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEAR 1602
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
N AGT +I LK+ P I + V S V +C V G P +V W R
Sbjct: 1603 NDAGTASCSI-ELKVKEPPTFIRELKPVEVVKYSDVELECEVTGTPPFEVTWLKNNREIR 1661
Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
L RV V +L + +D GEY C N G+ S S + + +PPS
Sbjct: 1662 SSKKYTLTDRVSVF---NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFIKK 1718
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ + A F T G P ++ W + + D + D V L I
Sbjct: 1719 IENTTTVLKSSATFQSTVAGSPPISITWLKDDQI------LDEDDNVYISFVDSVATLQI 1772
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
D N C A N +G L V P I+ S K
Sbjct: 1773 RSVD-NGHSGRYTCQAKNESGVERCYAFLLV----QEPAQIVEKAKSVDVTE-KDPMTLE 1826
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGK 475
C TPE + W +G+ ++ + +++ N + ++ + K DSG YT + G
Sbjct: 1827 CVVAGTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGS 1886
Query: 476 YVWSGAL-LVDSPINPN 491
L ++D I P+
Sbjct: 1887 SSCDAYLRVLDQNIPPS 1903
Score = 120 bits (290), Expect = 2e-26
Identities = 127/492 (25%), Positives = 205/492 (41%), Gaps = 25/492 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T E P + P V V T G+P ++W+KG +V +I
Sbjct: 3493 LTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDF 3552
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124
+ L + ++G Y C TN G+A + T H+ V ++ + S + G
Sbjct: 3553 VTELELFEVQP-LESGDYSCLVTNDAGSA---SCTTHLFVKEPATFVKRLADFSVETGSP 3608
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
+VLE G+P +V W K+ + + + + ++ I ++ D +Y C+
Sbjct: 3609 IVLEATYT-GTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIE 3667
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGG 242
N AG ++ A + + PY I E V A G T QC+V G P + W +
Sbjct: 3668 NEAG-QDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVDGTPEIRISWYKEHTKLR 3726
Query: 243 NMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
+ P +++ ++ SL ++ V +D GEYSC+A+NSVGAV++S L + PP
Sbjct: 3727 SAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASSAVLVIKARKLPPFFARK 3786
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V+ G F C G + W +G ++ + D T+ V L I
Sbjct: 3787 LKDVHETLGFPVAFECRINGSEPLQVSWYKDG---VL---LKDDANLQTSFVHNVATLQI 3840
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
TD++ CSA N G++ KL ++ + PP P + L + F
Sbjct: 3841 LQTDQSHI-GQYNCSASNPLGTASSSAKLILS--EHEVPPFFDLKPVSVDLALGESGTFK 3897
Query: 419 CTAICTPEPIIAWYFEGEALIQ--NHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
C T I W + + N++ V N TL + + K D+G YTC AS+ GK
Sbjct: 3898 CHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGK 3957
Query: 476 YVWSGALLVDSP 487
S L V P
Sbjct: 3958 DSCSAQLGVQEP 3969
Score = 119 bits (287), Expect = 6e-26
Identities = 125/493 (25%), Positives = 204/493 (41%), Gaps = 27/493 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+T E P +++P + V + T G+P + W++G +V +I
Sbjct: 2552 LTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDT 2611
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDT 124
+ L + + S +G Y C +N+ G A + T + V L+ S S + G +
Sbjct: 2612 VAELELFNIDI-SQSGEYTCVVSNNAGQA---SCTTRLFVKEPAAFLKRLSDHSVEPGKS 2667
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
++LE G+ +V WKK+G + + + ++ I ++ + DAG+Y C
Sbjct: 2668 IILES-TYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIE 2726
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW-RRSAGGG 242
N AG R+ A + PY +T E + A G SV+ QC+V G P V W +
Sbjct: 2727 NEAG-RDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSWYKGDTKLR 2785
Query: 243 NMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
P R ++ +L + V + D GEY+C+AENS+G S+ + + PPS
Sbjct: 2786 PTPEYRTYFTNNVATLVFNKVNINDSGEYTCKAENSIGTASSKTVFRIQERQLPPSFARQ 2845
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH-ATAVFDGVTVLT 357
+ G TC G + W +G + RD + T+ D V L
Sbjct: 2846 LKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDG-------VLLRDHENLQTSFVDNVATLK 2898
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I TD + S CSA N G++ +L T+ + + P P + + A F
Sbjct: 2899 ILQTDLSHS-GQYSCSASNPLGTASSSARL--TAREPKKSPFFDIKPVSIDVIAGESADF 2955
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHG 474
C I W + + + +T N L + + K DSG YTC A++ G
Sbjct: 2956 ECHVTGAQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVG 3015
Query: 475 KYVWSGALLVDSP 487
K + S L V P
Sbjct: 3016 KDMCSAQLSVKEP 3028
Score = 118 bits (285), Expect = 1e-25
Identities = 115/486 (23%), Positives = 190/486 (39%), Gaps = 22/486 (4%)
Query: 10 EAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
E P +++ VA+ + L C+ GSP + W++ + ++ +
Sbjct: 3027 EPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVSWFRNDSELHESWKYNMSFINSVAL 3086
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
L D+G Y CEA N G A A A F +P + +G V+L+
Sbjct: 3087 LTINEASAE-DSGDYICEAHNGVGDASCSTALTVKAP--PVFTQKPSPVGALKGSDVILQ 3143
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAG 187
C G+P V W K+ + + ++ NL I + +D G Y C A N G
Sbjct: 3144 C-EISGTPPFEVVWVKDRKQVRNSKKFKITSKHFDTNLHILNLEASDVGEYHCKATNEVG 3202
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMP 245
+ ++ ++K P + D G +V + V G V+W + G
Sbjct: 3203 S-DTCSCSVKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRESE 3261
Query: 246 LGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
R+ +D+ +L+L + ++ G+Y C+ +N G S LTV +P I P + V
Sbjct: 3262 NTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTV 3321
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
+GN C TG PE + W +G +S D H + V L I + +
Sbjct: 3322 TTGNPFALECVVTGTPELSAKWFKDGRE------LSADSKHHITFINKVASLKIPCAEMS 3375
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D + N G S ++V D PP + + + V C +
Sbjct: 3376 D-KGLYSFEVKNSVGKS--NCTVSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGS 3432
Query: 425 PEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
+ W+ +G ++ + + N TL L L+ SD+G YTCVA++ G S
Sbjct: 3433 APISVGWFQDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAV 3492
Query: 482 LLVDSP 487
L V P
Sbjct: 3493 LTVQEP 3498
Score = 116 bits (279), Expect = 5e-25
Identities = 126/493 (25%), Positives = 195/493 (39%), Gaps = 37/493 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P P V ++ +L C G+P + WYK + S I +
Sbjct: 2180 EPPVFSSFPPIVETLKNAEVSLECELSGTPPFEVVWYKDKRQLRSSKKYKIASKNFHTSI 2239
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
+ SD G Y C+A N G+ + + L+E F + S G+ L
Sbjct: 2240 HILNVDT-SDIGEYHCKAQNEVGS----DTCVCTVKLKEPPRFVSKLNSLTVVAGEPAEL 2294
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDS-RMHLVDG-GNLVIQDARQTDAGRYQCIARNA 185
+ G+ V W K + ++ + ++ R+ V+ L A +AG+Y C +N
Sbjct: 2295 QA-SIEGAQPIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKND 2353
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G RE+ +ATL + ++ + G + T +C+V G P V W + G +
Sbjct: 2354 GGMREN-MATLMVLEPAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKD---GKLL 2409
Query: 246 LGRVK-----VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINL 297
K SLR+ +V D G Y+ + +N+VG S + + V D PPS
Sbjct: 2410 TSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAVPPSFTR 2469
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
+ G C G ++ W E + + S KY T D V L
Sbjct: 2470 RLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIV-----SGAKYQ-TTFSDNVCTLQ 2523
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+N D +D N C A N AGS R LTV PP + + LP K++ F
Sbjct: 2524 LNSLDSSDMGN-YTCVAANVAGSDECRAVLTV----QEPPSFVKEPEPLEVLPGKNV-TF 2577
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHG 474
TP + W+ L++ R N+ + T L L ++D S SG YTCV S+ G
Sbjct: 2578 TSVIRGTPPFKVNWFRGARELVKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG 2637
Query: 475 KYVWSGALLVDSP 487
+ + L V P
Sbjct: 2638 QASCTTRLFVKEP 2650
Score = 116 bits (279), Expect = 5e-25
Identities = 125/490 (25%), Positives = 212/490 (43%), Gaps = 35/490 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFLR 70
P +++ D++ + L G+ ++ W+K G +V + I + + L+
Sbjct: 4157 PRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSENIATLQ 4216
Query: 71 ATHGRVH-SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLE 128
+ RV ++AG Y C+ N G ATL +VL +E PES + GDT LE
Sbjct: 4217 FS--RVEPANAGKYTCQIKNDAGMQECF-ATL--SVLEPATIVEKPESIKVTTGDTCTLE 4271
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
C G+PE + W K+G+ L D ++ + L I + +D+G Y +N G
Sbjct: 4272 CTVA-GTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVG 4330
Query: 188 TRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
++S A+L++ + P ++ +GSSV +C+V G P V W G +
Sbjct: 4331 -KDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHE--GNEI 4387
Query: 245 PLGRV--KVLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
GR L D + L +L +D G+Y+C A N G+ S LTV +PPS P+
Sbjct: 4388 SSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPD 4447
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
++V +G FT G P ++ W +G+ ++ PG D+ + ++ D V L + D
Sbjct: 4448 PMDVLTGTNVTFTSIVKGTPPFSVSW-FKGSSELV-PG---DRCN-VSLEDSVAELELFD 4501
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
D + S C N AG + L + + P ++ ++ + T
Sbjct: 4502 VDTSQS-GEYTCIVSNEAGKASCTTHLYI-----KAPAKFVKRLNDYSIEKGKPLILEGT 4555
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYV 477
TP + W G + + R N+T + ++ S D+G Y C + GK
Sbjct: 4556 FTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVEDAGQYNCYIENASGKDS 4615
Query: 478 WSGALLVDSP 487
S +L+ P
Sbjct: 4616 CSAQILILEP 4625
Score = 115 bits (277), Expect = 9e-25
Identities = 125/481 (25%), Positives = 192/481 (39%), Gaps = 30/481 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E PY ++Q V V+ A+L C+ G+P + WYKG + T + + L
Sbjct: 4624 EPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATL 4683
Query: 70 RATHGRVHSDAGVYWCEATNSYG-TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
+ +D+G Y C+A NS G + S T+ L F + Q G VV +
Sbjct: 4684 VFNQVDI-NDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFD 4742
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG 187
C GS +V W K+G+ L + + +D L I ++ AG+Y C A N G
Sbjct: 4743 C-AISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIG 4801
Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGG 241
+ S+ + K P+ V A G S F+C V G V W R G
Sbjct: 4802 SASSSARLILTEGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSG 4861
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLS 298
G + ++ + L + V D G+Y+C A N VG S + L + + PPS
Sbjct: 4862 GKYQISYLE--NSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKR 4919
Query: 299 -PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
+V GN + G T+ W N I P + + + VL
Sbjct: 4920 LSETVEETEGNSFKLEGRVAGSQPITVAW--YKNNIEIQPTSNCE----ITFKNNTLVLQ 4973
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+ ND+ C N AGS+ + + + + PP+ + T+
Sbjct: 4974 VRKAGMNDA-GLYTCKVSNDAGSALCTSSIVI--KEPKKPPVFDQHLTPVTVSEGEYVQL 5030
Query: 418 PCTAICTPEPI-IAWYFEGEALIQNHRRNVT-NDGTLV--LKDLDKSDSGTYTCVASSRH 473
C + EPI I W G + + R + + GT V L+D+ K+DSG Y C AS+
Sbjct: 5031 SC-HVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVA 5089
Query: 474 G 474
G
Sbjct: 5090 G 5090
Score = 115 bits (276), Expect = 1e-24
Identities = 118/490 (24%), Positives = 195/490 (39%), Gaps = 26/490 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
VT P + +P +T + A C G+P W K G + + I A
Sbjct: 210 VTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAEN 269
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
L ++ + D GVY C+A+N +G A A L + + + F E E QSA V
Sbjct: 270 KHILELSNLTIQ-DRGVYSCKASNKFG-ADICQAEL-IIIDKPHFIKELEPVQSAINKKV 326
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184
LEC + V W K+GQ L D ++ D L I A+ D+G Y C A N
Sbjct: 327 HLECQVDEDR-KVTVTWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASN 385
Query: 185 AAGTRESAIATLKIHIKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG--G 241
AG+ S AT+ + P + + + G S C++ G P+ V W ++
Sbjct: 386 EAGS-SSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELS 444
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
+ + V + L + +V + D G YSCEA N VG+ S S + + +PPS +
Sbjct: 445 ESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFIKTLEP 504
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
++ G A C +G + W + + + + + + + + N
Sbjct: 505 ADIVRGTNALLQCEVSGTGPFEISWFKDKKQ---IRSSKKYRLFSQKSLVCLEIFSFNSA 561
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
D + C N G + T PP + + + + V A
Sbjct: 562 DVGEYE----CVVANEVG----KCGCMATHLLKEPPTFVKK--VDDLIALGGQTVTLQAA 611
Query: 422 ICTPEPIIAWYFEGEALIQNH---RRNVTND-GTLVLKDLDKSDSGTYTCVASSRHGKYV 477
+ EPI + +G+ +I+ + + +N L++ D+ S G YTC+A + G
Sbjct: 612 VRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQT 671
Query: 478 WSGALLVDSP 487
G L+V P
Sbjct: 672 SVGELIVKEP 681
Score = 114 bits (274), Expect = 2e-24
Identities = 125/481 (25%), Positives = 196/481 (40%), Gaps = 40/481 (8%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I + + VA A C +P+ +W+K G + SI + + L
Sbjct: 120 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 179
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA-VLREEFRLEPESKQSAQGDTVVLEC 129
+V D G Y C+A+N YG+ S ATL V F P+S + G C
Sbjct: 180 ILRTQV-VDCGEYTCKASNEYGSV-SCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFIC 237
Query: 130 LPPRGSPEPNVYWKKNGQTL-------LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
G+P W+K+G L + D +++ H+++ NL IQ D G Y C A
Sbjct: 238 -TVTGTPVIETIWQKDGAALSPSPNWRISDAENK-HILELSNLTIQ-----DRGVYSCKA 290
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N G + A L I KP+ I E V + V +C+V D V W S G
Sbjct: 291 SNKFGA-DICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTW--SKDGQ 347
Query: 243 NMPLGR-VKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INL 297
+P G+ K+ +D +L + L D G Y C A N G+ S S +TV +PPS +
Sbjct: 348 KLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVREPPSFVKK 407
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
S + G AR C G P + W + N+ +S + +L
Sbjct: 408 VDPSYLMLPGESARLHCKLKGSPVIQVTW-FKNNKE-----LSESNTVRMYFVNSEAILD 461
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D DS + C AVN GS ++ + + PP + + A+
Sbjct: 462 ITDVKVEDS-GSYSCEAVNDVGSDSCSTEIVI-----KEPPSFIKTLEPADIVRGTNALL 515
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL---DKSDSGTYTCVASSRHG 474
C T I+W+ + + + + + + + +LV ++ + +D G Y CV ++ G
Sbjct: 516 QCEVSGTGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANEVG 575
Query: 475 K 475
K
Sbjct: 576 K 576
Score = 114 bits (274), Expect = 2e-24
Identities = 121/518 (23%), Positives = 203/518 (39%), Gaps = 27/518 (5%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
D ++ + +P L G+P ++ W K G+ V +I L V D
Sbjct: 4541 DYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSPILEIPSSTVE-D 4599
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEP 138
AG Y C N+ G + + + +L + ++ E + + GD+ L+C G+PE
Sbjct: 4600 AGQYNCYIENASG---KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQC-QLAGTPEI 4655
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAG--TRESAIAT 195
V W K L +MH + LV D+G Y C A N+ G + + +
Sbjct: 4656 GVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTV 4715
Query: 196 LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVLDD 254
+ + P DV G V F C + G V W + + P + LD+
Sbjct: 4716 QEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDN 4775
Query: 255 -GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD---PPSINLSPNSVNVESGNVA 310
+L + + G+YSC A N +G+ S+S L + + PP ++ V+ G A
Sbjct: 4776 TATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVDAVVGESA 4835
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
F C TG + W+ + +R I S KY + + + LT+ DK DS
Sbjct: 4836 DFECHVTGTQPIKVSWAKD-SREI----RSGGKYQISYL-ENSAHLTVLKVDKGDS-GQY 4888
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI-I 429
C AVN G +L + + PP T S + + + +PI +
Sbjct: 4889 TCYAVNEVGKDSCTAQLNIK--ERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITV 4946
Query: 430 AWYFEGEALIQNHRRNVT-NDGTLVL--KDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
AWY + +T + TLVL + +D+G YTC S+ G + + ++++
Sbjct: 4947 AWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKE 5006
Query: 487 PINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
P P + V+ G + H + + W
Sbjct: 5007 PKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQW 5044
Score = 108 bits (259), Expect = 1e-22
Identities = 121/490 (24%), Positives = 190/490 (38%), Gaps = 30/490 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P +++ D+ Q TL GS ++ W KG ++ D + + G+ L
Sbjct: 587 EPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVL 646
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQGDTVVL 127
++ S G Y C A N G+ S + +++E ++ E Q GD L
Sbjct: 647 IIPDVQI-SFGGKYTCLAENEAGSQTS----VGELIVKEPAKIIERAELIQVTAGDPATL 701
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
E G+PE W K+G+ L+ R+ + L A D+G+Y N
Sbjct: 702 E-YTVAGTPELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEV 760
Query: 187 GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
G+ E+ L I P+ +V + + C++ G V W + G
Sbjct: 761 GSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCKIAGSLPMRVSWFKD-GKEIA 819
Query: 245 PLGRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
R ++ SL + V + D G ++C A NSVG+ +SG L V +PPS P S
Sbjct: 820 ASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGALIVQEPPSFVTKPGS 879
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+V G+ T G T+ W +GN+ ++ G Y + L + T
Sbjct: 880 KDVLPGSAVCLKSTFQGSTPLTIRW-FKGNKELVSGGSC---YITKEALESSLELYLVKT 935
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
+DS T C N AG L V P + +Q L C
Sbjct: 936 --SDS-GTYTCKVSNVAGGVECSANLFV----KEPATFVEKLEPSQLLKKGDATQLACKV 988
Query: 422 ICTPEPIIAWYFEGEALIQN--HRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
TP I W+ + ++ HR + V + L L D+ DSG Y C A + G
Sbjct: 989 TGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHC 1048
Query: 479 SGALLV-DSP 487
S ++V +SP
Sbjct: 1049 SSIVIVKESP 1058
Score = 107 bits (257), Expect = 2e-22
Identities = 113/425 (26%), Positives = 183/425 (43%), Gaps = 37/425 (8%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSP 136
S++G Y C+ N G R + + VL +E PE G+ LEC+ G+P
Sbjct: 3282 SNSGKYICQIKNDAGM---RECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVT-GTP 3337
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
E + W K+G+ L D + ++ +L I A +D G Y +N+ G T
Sbjct: 3338 ELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSN---CT 3394
Query: 196 LKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK 250
+ +H+ P I +DV A G+SV +CRV G V W + GN + K
Sbjct: 3395 VSVHVSDRIVPPSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQD---GNEIVSGPK 3451
Query: 251 VLDDGS-----LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
S L L + +D G Y+C A N G+ S LTV +PPS +P+SV V
Sbjct: 3452 CQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVL 3511
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G FT G P + W +G+R ++ PG S + ++ D VT L + + +
Sbjct: 3512 PGMSLTFTSVIRGTPPFKVKW-FKGSRELV-PGESCN----ISLEDFVTELELFEVQPLE 3565
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
S C N AGS+ L V + P ++ ++ S V T TP
Sbjct: 3566 S-GDYSCLVTNDAGSASCTTHLFV-----KEPATFVKRLADFSVETGSPIVLEATYTGTP 3619
Query: 426 EPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKS--DSGTYTCVASSRHGKYVWSGAL 482
++W + + Q+ R ++T + + +L+ L+ + D Y+C+ + G+ + +
Sbjct: 3620 PISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALV 3679
Query: 483 LVDSP 487
V P
Sbjct: 3680 SVLEP 3684
Score = 105 bits (251), Expect = 1e-21
Identities = 124/502 (24%), Positives = 190/502 (37%), Gaps = 42/502 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P II D + QPA CR G+ + WY + + + L
Sbjct: 10 PAIITPLQDTVTSEGQPARFQCRVSGTDLK-VSWYSKDKKIKPSRFFRMTQFEDTYQLEI 68
Query: 72 THGRVHSDAGVYWCEATNSYGTARSR--------NATLHVAVLRE---EFRLEPESKQSA 120
D G Y A N+ G S + LH + +E E + P K+
Sbjct: 69 AEA-YPEDEGTYTFVANNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKI 127
Query: 121 QGDTVVLECLPP-----RGSPEPNVYWKKNGQTLL-FDGDSRMHLVDGGNLVIQDARQTD 174
+ V L L + +P W K G+ + D S +L I + D
Sbjct: 128 EPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVD 187
Query: 175 AGRYQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
G Y C A N G+ S ATL + P ++ P+ + G + F C V G P+ +
Sbjct: 188 CGEYTCKASNEYGS-VSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIE 246
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+W++ G P ++ D + L L N+ + D G YSC+A N GA L +
Sbjct: 247 TIWQKD-GAALSPSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELII 305
Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
D P V C + T+ WS +G + + PG K +
Sbjct: 306 IDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQK--LPPG----KDYKICF 359
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN-GPSNQT 408
D + L I DS T VC+A N AGSS +TV PP + PS
Sbjct: 360 EDKIATLEIPLAKLKDS-GTYVCTASNEAGSSSCSATVTVR----EPPSFVKKVDPSYLM 414
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTY 465
LP +S A C +P + W+ + L +++ V ++ L + D+ DSG+Y
Sbjct: 415 LPGES-ARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSY 473
Query: 466 TCVASSRHGKYVWSGALLVDSP 487
+C A + G S +++ P
Sbjct: 474 SCEAVNDVGSDSCSTEIVIKEP 495
Score = 103 bits (246), Expect = 5e-21
Identities = 122/512 (23%), Positives = 189/512 (36%), Gaps = 34/512 (6%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C+ GS ++ W+ +VS + + L+ + SD G Y C A N
Sbjct: 2484 LECKVAGSSPISVAWFHEKTKIVSGAKYQTTFSDNVCTLQL-NSLDSSDMGNYTCVAANV 2542
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
G+ R A L V F EPE + G V + RG+P V W + + L+
Sbjct: 2543 AGSDECR-AVLTVQE-PPSFVKEPEPLEVLPGKNVTFTSVI-RGTPPFKVNWFRGARELV 2599
Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPE 209
++ D L + + + +G Y C+ N AG + S L + +
Sbjct: 2600 KGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAG-QASCTTRLFVKEPAAFLKRLS 2658
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR----VKVLDDGSLRLDNVILA 265
D + G S+ + G V W++ G N+ V L + N
Sbjct: 2659 DHSVEPGKSIILESTYTGTLPISVTWKKD--GFNITTSEKCNIVTTEKTCILEILNSTKR 2716
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
D G+YSCE EN G ++ +PP + G+ C G PE T+
Sbjct: 2717 DAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVS 2776
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W +G+ T + P Y + V L N + NDS C A N G++
Sbjct: 2777 W-YKGD-TKLRPTPEYRTYFT----NNVATLVFNKVNINDS-GEYTCKAENSIGTA--SS 2827
Query: 386 KLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT---PEPI-IAWYFEGEALIQN 441
K + + PP + Q I+ P T C PI + WY +G L+++
Sbjct: 2828 KTVFRIQERQLPPSF----ARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYRDG-VLLRD 2882
Query: 442 HRRNVT----NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
H T N TL + D S SG Y+C AS+ G S L P +
Sbjct: 2883 HENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKP 2942
Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+ + G H + ++WS++NK
Sbjct: 2943 VSIDVIAGESADFECHVTGAQPMRITWSKDNK 2974
Score = 99.1 bits (236), Expect = 8e-20
Identities = 125/504 (24%), Positives = 195/504 (38%), Gaps = 45/504 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFL 69
P Q DV P +C GS ++ WYK G + + S L +
Sbjct: 4722 PSFSRQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNI 4781
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF---RLEPESKQSAQGDTVV 126
T S AG Y C ATN G+A S + F RL P + G++
Sbjct: 4782 FKTD---RSLAGQYSCTATNPIGSASSSARLILTEGKNPPFFDIRLAPVD--AVVGESAD 4836
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCIARNA 185
EC G+ V W K+ + + G ++ +L + +L + + D+G+Y C A N
Sbjct: 4837 FEC-HVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNE 4895
Query: 186 AGTRESAIATLKIH---IKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRRSAGG 241
G ++S A L I I P + V +T G+S + RV G V W ++
Sbjct: 4896 VG-KDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQPITVAWYKN-NI 4953
Query: 242 GNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSI 295
P ++ + L++ + D G Y+C+ N G+ + + + +P P
Sbjct: 4954 EIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEPKKPPVF 5013
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+ V V G + +C G + W G I P D+ + + G V
Sbjct: 5014 DQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGRE--IKPS---DRC-SFSFASGTAV 5067
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----------IITNGPS 405
L + D K DS + VC A N AGS + K+T+ P + P
Sbjct: 5068 LELRDVAKADSGD-YVCKASNVAGSDTTKSKVTIKDKPAVAPATKKAAVDGRLFFVSEPQ 5126
Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDGT---LVLKDLDKSD 461
+ + K+ A F P P + W + L Q R + G L ++D K+D
Sbjct: 5127 SIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTD 5186
Query: 462 SGTYTCVASSRHGKYVWSGALLVD 485
SG Y CVA + HG+ + L VD
Sbjct: 5187 SGLYRCVAFNEHGEIESNVNLQVD 5210
Score = 97.1 bits (231), Expect = 3e-19
Identities = 126/526 (23%), Positives = 204/526 (38%), Gaps = 32/526 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFF 68
E P + + +TV +PA L G+ ++W K V+ ++ I +
Sbjct: 2273 EPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITFVENVAT 2332
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
L+ ++AG Y C+ N G R ATL VL +E + G+T L
Sbjct: 2333 LQFAKAEP-ANAGKYICQIKND-GGMRENMATL--MVLEPAVIVEKAGPMTVTVGETCTL 2388
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
EC G+PE +V W K+G+ L + + +L I + DAG Y +N
Sbjct: 2389 EC-KVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQVQNNV 2447
Query: 187 GTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
G + S A + + + P ++ G+S +C+V G V W
Sbjct: 2448 G-KSSCTAVVDVSDRAVPPSFTRRLKNTGGVLGASCILECKVAGSSPISVAWFHEKTKIV 2506
Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
D +L+L+++ +D G Y+C A N G+ LTV +PPS P
Sbjct: 2507 SGAKYQTTFSDNVCTLQLNSLDSSDMGNYTCVAANVAGSDECRAVLTVQEPPSFVKEPEP 2566
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ V G FT G P + W G R ++ G + Y D V L + +
Sbjct: 2567 LEVLPGKNVTFTSVIRGTPPFKVNW-FRGARELV-KGDRCNIYFE----DTVAELELFNI 2620
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTA 421
D + S C N AG + +L V P + + P KS+ + T
Sbjct: 2621 DISQS-GEYTCVVSNNAGQASCTTRLFV----KEPAAFLKRLSDHSVEPGKSI-ILESTY 2674
Query: 422 ICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVW 478
T + W +G + + + N VT + T +L+ L+ K D+G Y+C + G+ V
Sbjct: 2675 TGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEILNSTKRDAGQYSCEIENEAGRDV- 2733
Query: 479 SGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSW 524
GAL+ S + P + + G +T+SW
Sbjct: 2734 CGALV--STLEPPYFVTELEPLEAAVGDSVSLQCQVAGTPEITVSW 2777
Score = 97.1 bits (231), Expect = 3e-19
Identities = 121/527 (22%), Positives = 194/527 (36%), Gaps = 26/527 (4%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I + DV L CR GS ++ W++ G +VS + + L
Sbjct: 3406 PSFIRKLKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSFSENVCTLNL 3465
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ SD G+Y C A N G+ +A L V F P+S + G ++ +
Sbjct: 3466 SLLEP-SDTGIYTCVAANVAGSDEC-SAVLTVQE-PPSFEQTPDSVEVLPGMSLTFTSVI 3522
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRE 190
RG+P V W K + L+ + L D L + + + ++G Y C+ N AG
Sbjct: 3523 -RGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAG--- 3578
Query: 191 SAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
SA T + +K + D +TGS + + G P V W + +
Sbjct: 3579 SASCTTHLFVKEPATFVKRLADFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERC 3638
Query: 249 VKVLDDGSLRLDNV--ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVES 306
+ + S L+ + + D +YSC EN G ++V +PP V
Sbjct: 3639 SITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPPYFIEPLEHVEAVI 3698
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G A C G PE + W E + P + + V L IN D +D
Sbjct: 3699 GEPATLQCKVDGTPEIRISWYKEHTKLRSAPA------YKMQFKNNVASLVINKVDHSDV 3752
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N G+ L + + + PP + + F C I E
Sbjct: 3753 -GEYSCKADNSVGAVASSAVLVIKAR--KLPPFFARKLKDVHETLGFPVAFECR-INGSE 3808
Query: 427 PI-IAWYFEGEALIQNHRRN---VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGAL 482
P+ ++WY +G L + V N TL + D+S G Y C AS+ G S L
Sbjct: 3809 PLQVSWYKDGVLLKDDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKL 3868
Query: 483 LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
++ P + V G H + ++W+++N+
Sbjct: 3869 ILSEHEVPPFFDLKPVSVDLALGESGTFKCHVTGTAPIKITWAKDNR 3915
Score = 96.3 bits (229), Expect = 6e-19
Identities = 107/488 (21%), Positives = 186/488 (38%), Gaps = 27/488 (5%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P I++ + T AT GSP +I W K ++ D + I + L
Sbjct: 1711 EPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDSVATL 1770
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS--AQGDTVVL 127
+ + +G Y C+A N G R L ++E ++ ++K + D + L
Sbjct: 1771 QI-RSVDNGHSGRYTCQAKNESGVERCYAFLL----VQEPAQIVEKAKSVDVTEKDPMTL 1825
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAA 186
EC+ G+PE V W K+G+ ++ M + + IQ + D+G+Y N
Sbjct: 1826 ECVVA-GTPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDF 1884
Query: 187 GTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
G+ ++ + L +I P + GSS+ +C+V G W + +
Sbjct: 1885 GSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKEIST 1944
Query: 245 PLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
V + S+ L+ N+ L D Y+C+ N G + SG LTV +PPS + P
Sbjct: 1945 SAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQ 2004
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
+ F G P + W + + P +T+ + +V D
Sbjct: 2005 QAIPDSTVEFKAILKGTPPFKIKWFKDDVELVSGPKCFIGLEGSTSFLNLYSV----DAS 2060
Query: 363 KNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI 422
K C N GS L VT PP + +++ + + C
Sbjct: 2061 KT---GQYTCHVTNDVGSDSCTTMLLVT----EPPKFVKKLEASKIVKAGDSSRLECKIA 2113
Query: 423 CTPEPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWS 479
+PE + W+ L + + +T + + + +L DSG + C A + G S
Sbjct: 2114 GSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCS 2173
Query: 480 GALLVDSP 487
++V P
Sbjct: 2174 TKVIVKEP 2181
Score = 94.7 bits (225), Expect = 2e-18
Identities = 113/472 (23%), Positives = 178/472 (37%), Gaps = 24/472 (5%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+ P+ I++ V A ++ L C+ + W K G + I + L
Sbjct: 307 DKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFEDKIATL 366
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
++ D+G Y C A+N G++ S +AT+ V + S G++ L C
Sbjct: 367 EIPLAKL-KDSGTYVCTASNEAGSS-SCSATVTVREPPSFVKKVDPSYLMLPGESARLHC 424
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+GSP V W KN + L RM+ V+ ++ I D + D+G Y C A N G+
Sbjct: 425 -KLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGS 483
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+S + I P I E G++ QC V G ++ W + +
Sbjct: 484 -DSCSTEIVIKEPPSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKDKKQIRSSK-K 541
Query: 249 VKVLDDGSL---RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
++ SL + + AD GEY C N VG + +PP+ + +
Sbjct: 542 YRLFSQKSLVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIAL 601
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G G ++ W ++G I G + + +GV VL I D +
Sbjct: 602 GGQTVTLQAAVRGSEPISVTW-MKGQEVIREDGKIKMSFS-----NGVAVLIIPDVQISF 655
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
C A N AGS G+L V P II Q + A T TP
Sbjct: 656 G-GKYTCLAENEAGSQTSVGELIV----KEPAKIIERAELIQ-VTAGDPATLEYTVAGTP 709
Query: 426 EPIIAWYFEGEALIQNHRRNVT---NDGTLVLKDLDKSDSGTYTCVASSRHG 474
E WY +G L+ + + ++ N L + DSG YT S+ G
Sbjct: 710 ELKPKWYKDGRPLVASKKYRISFKNNVAQLKFYSAELHDSGQYTFEISNEVG 761
Score = 94.3 bits (224), Expect = 2e-18
Identities = 113/465 (24%), Positives = 176/465 (37%), Gaps = 26/465 (5%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P + +P V L GS IRW+KG +VS I L
Sbjct: 869 EPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSL 928
Query: 70 RATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
+ SD+G Y C+ +N G S N + E +LEP S+ +GD L
Sbjct: 929 ELYLVKT-SDSGTYTCKVSNVAGGVECSANLFVKEPATFVE-KLEP-SQLLKKGDATQLA 985
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAG 187
C G+P + W N + + RM V+ ++ + D D+G Y C A+N AG
Sbjct: 986 C-KVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAG 1044
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
+ + + + PY + + V V G P ++ W +
Sbjct: 1045 SDHCSSIVI-VKESPYFTKEFKPIEVLKEYDVMLLAEVAGTPPFEITWFKDNTILRSGRK 1103
Query: 248 RVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
+ D SL++ + AD GEY C N VG+ S +T+ +PPS S +
Sbjct: 1104 YKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVGSSICSARVTLREPPSFIKKIESTSSL 1163
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD-KN 364
G A F T G T+ W + + ++ D + V L ++ + K+
Sbjct: 1164 RGGTAAFQATLKGSLPITVTWLKDSDE------ITEDDNIRMTFENNVASLYLSGIEVKH 1217
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D + VC A N AG L+V + P IT + + A T
Sbjct: 1218 DGK--YVCQAKNDAGIQRCSALLSV-----KEPATITEEAVSIDVTQGDPATLQVKFSGT 1270
Query: 425 PEPIIAWYFEGEALIQNHRRNVT-NDGTLVLK--DLDKSDSGTYT 466
E W+ +G+ L + ++ D +LK +K DSG YT
Sbjct: 1271 KEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYT 1315
Score = 94.3 bits (224), Expect = 2e-18
Identities = 116/490 (23%), Positives = 179/490 (36%), Gaps = 23/490 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
VT E P I++ + R A GS + W K + D + +
Sbjct: 1145 VTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENN 1204
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+ L + V D G Y C+A N G R +A L V E S QGD
Sbjct: 1205 VASLYLSGIEVKHD-GKYVCQAKNDAGIQRC-SALLSVKE-PATITEEAVSIDVTQGDPA 1261
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184
L+ + G+ E W K+GQ L ++ + D +++ I + D+G Y +N
Sbjct: 1262 TLQ-VKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDSGEYTFEVQN 1320
Query: 185 AAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
G ++ I L + I P + + + GS + +C V G + W +
Sbjct: 1321 DVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQWFKDDQEI 1380
Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
+ D + L + + D G Y+C A N G SG+LTV +PP P
Sbjct: 1381 SASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTVKEPPYFVEKPQ 1440
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
S +V + G T+ W + + G +R + D T L +
Sbjct: 1441 SQDVNPNTRVQLKALVGGTAPMTIKWFKDNKE--LHSGAARSVWKD----DTSTSLELFA 1494
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
DS T +C N G++ + L V PP I L F C
Sbjct: 1495 AKATDS-GTYICQLSNDVGTATSKATLFV----KEPPQFIKKPSPVLVLRNGQSTTFECQ 1549
Query: 421 AICTPEPIIAWYFEGEAL--IQNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
TP+ ++WY +G + IQ H + + T + +SGTY C A + G
Sbjct: 1550 ITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARVENSGTYVCEARNDAGTAS 1609
Query: 478 WSGALLVDSP 487
S L V P
Sbjct: 1610 CSIELKVKEP 1619
Score = 80.6 bits (190), Expect = 3e-14
Identities = 109/520 (20%), Positives = 209/520 (40%), Gaps = 44/520 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
+ C+ GS + +W+K G + + ++ L + + A Y C+ +N
Sbjct: 1921 MECKVSGSLPISAQWFKDGKEISTSAKYRLVCHERSVSLEVNNLELEDTAN-YTCKVSNV 1979
Query: 91 YGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
G +A + ++E F ++P +Q+ TV + + +G+P + W K+
Sbjct: 1980 AGD----DACSGILTVKEPPSFLVKPGRQQAIPDSTVEFKAIL-KGTPPFKIKWFKDDVE 2034
Query: 149 LLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL 204
L+ G ++G NL DA +T G+Y C N G+ +S L + P
Sbjct: 2035 LV-SGPKCFIGLEGSTSFLNLYSVDASKT--GQYTCHVTNDVGS-DSCTTMLLVTEPPKF 2090
Query: 205 ITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG---RVKVLDDGS-LRL 259
+ E + + G S +C++ G P V+W R+ +P R+ +D + +++
Sbjct: 2091 VKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEH--ELPASDKYRMTFIDSVAVIQM 2148
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
+N+ D G++ CEA+N G+ S S + V +PP + P V C +G
Sbjct: 2149 NNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAEVSLECELSGT 2208
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
P + W + + + K + + +L ++ +D + C A N G
Sbjct: 2209 PPFEVVWYKDKRQ---LRSSKKYKIASKNFHTSIHILNVDTSDIGEYH----CKAQNEVG 2261
Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI 439
S V + + PP + ++ T+ A + + W E E +I
Sbjct: 2262 SD-----TCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVI 2316
Query: 440 ---QNHRRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFF 495
+N R V N TL + +++G Y C + G L+V + P +
Sbjct: 2317 RESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMV---LEPAVIVE 2373
Query: 496 RAADVSSLPGPPTKPITHNVTDT-SVTLSWSQNNKIGSSS 534
+A ++ G T + V T +++ W ++ K+ +SS
Sbjct: 2374 KAGPMTVTVG-ETCTLECKVAGTPELSVEWYKDGKLLTSS 2412
Score = 58.4 bits (135), Expect = 1e-07
Identities = 91/356 (25%), Positives = 132/356 (37%), Gaps = 47/356 (13%)
Query: 6 VTSGEAPYIIE---QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL- 61
+T G+ P + P+D V + A C G+ + W K + S I
Sbjct: 4811 LTEGKNPPFFDIRLAPVDAVVG--ESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISY 4868
Query: 62 --PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLE-PES 116
+ L L+ G D+G Y C A N G S A L++ ++ F E+
Sbjct: 4869 LENSAHLTVLKVDKG----DSGQYTCYAVNEVGKD-SCTAQLNIKERLIPPSFTKRLSET 4923
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTD 174
+ +G++ LE GS V W KN + + + + LV+Q A D
Sbjct: 4924 VEETEGNSFKLEGRVA-GSQPITVAWYKNNIEIQPTSNCEITFKNN-TLVLQVRKAGMND 4981
Query: 175 AGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDP 229
AG Y C N AG SA+ T I IK P V G V C V G
Sbjct: 4982 AGLYTCKVSNDAG---SALCTSSIVIKEPKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSE 5038
Query: 230 LPDVLWRRSAGGGNMPLGRVKV-LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGY 286
+ W + AG P R G+ L L +V AD G+Y C+A N G+ +
Sbjct: 5039 PIRIQWLK-AGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSK 5097
Query: 287 LTVYDPPSIN---------------LSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
+T+ D P++ P S+ V A F G P P + W+
Sbjct: 5098 VTIKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWT 5153
Score = 49.6 bits (113), Expect = 7e-05
Identities = 103/481 (21%), Positives = 182/481 (37%), Gaps = 52/481 (10%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
+ + +P + V AT + GG P P ++W KG ++ R + G
Sbjct: 5120 FFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEI 5179
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
+D+G+Y C A N +G S N L V +++ ++E + + + T +L+
Sbjct: 5180 RDTTKTDSGLYRCVAFNEHGEIES-NVNLQVDERKKQEKIEGDLRAMLK-KTPILKKGAG 5237
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLV-----IQDARQTDAGRYQCIARNAA 186
+ KN ++ +RM+ + D L+ ++ +++ + R + +
Sbjct: 5238 EEEEIDIMELLKNVDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERS 5297
Query: 187 GTRESAIATLKIHIKPYL-----ITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRS 238
E L I+ L +T +D+ QT + F+ + + P++
Sbjct: 5298 ERDEKEFEELVSFIQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKIN-YPEIKLSWY 5356
Query: 239 AGGGNM-PLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
G + P + ++ DG +LR+ N L D+G Y G AS LTV +P +
Sbjct: 5357 KGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVC----GPHIASAKLTVIEP-A 5411
Query: 295 INLSPNSVNVESGNVARFTCTATGR---PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
V ++ G TCT T + P W G I R H T V
Sbjct: 5412 WERHLQDVTLKEGQ----TCTMTVQFSVPNVKSEWFRNGR---ILKPQGR---HKTEVEH 5461
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
V LTI D D + C + S+ +R + P T N +
Sbjct: 5462 KVHKLTIADVRAED-QGQYTCKYEDLETSAELR--------IEAEPIQFTKRIQNIVVSE 5512
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCV 468
A F C + + I+ WY L ++ + N NDG + + ++ D G Y+ +
Sbjct: 5513 HQSATFECE-VSFDDAIVTWYKGPTELTESQKYNFRNDGRCHYMTIHNVTPDDEGVYSVI 5571
Query: 469 A 469
A
Sbjct: 5572 A 5572
Score = 39.5 bits (88), Expect = 0.072
Identities = 31/121 (25%), Positives = 56/121 (46%), Gaps = 12/121 (9%)
Query: 122 GDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRY 178
G + + ECL SP + W K+G + + + DG + L I D + +DAG Y
Sbjct: 7820 GSSAIFECLV---SPSTAITTWMKDGSNIR-ESPKHRFIADGKDRKLHIIDVQLSDAGEY 7875
Query: 179 QCIAR--NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
C+ R N T + + ++ ++ ++ T E+V G + C + + DV+WR
Sbjct: 7876 TCVLRLGNKEKTSTAKLVVEELPVR-FVKTLEEEVTVVKGQPLYLSCELNKE--RDVVWR 7932
Query: 237 R 237
+
Sbjct: 7933 K 7933
Score = 33.1 bits (72), Expect = 6.2
Identities = 28/126 (22%), Positives = 48/126 (38%), Gaps = 5/126 (3%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVL 454
P+I + + +A F C P W+ G + ++ + ++ + +L +
Sbjct: 121 PVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEI 180
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514
D G YTC AS+ +G + L V P R +++ G K I
Sbjct: 181 LRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTF-LSRPKSLTTFVGKAAKFIC-T 238
Query: 515 VTDTSV 520
VT T V
Sbjct: 239 VTGTPV 244
Score = 32.7 bits (71), Expect = 8.2
Identities = 42/167 (25%), Positives = 62/167 (37%), Gaps = 16/167 (9%)
Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSL 257
IK ++T E V GSS F+C V + + P R + D D L
Sbjct: 7808 IKDIILTESEFV----GSSAIFECLVSPSTAITTWMKDGSNIRESPKHRF-IADGKDRKL 7862
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP--SINLSPNSVNVESGNVARFTCT 315
+ +V L+D GEY+C +++ L V + P + V V G +C
Sbjct: 7863 HIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLYLSCE 7922
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
E + W +G + PG V + LTIND D
Sbjct: 7923 L--NKERDVVWRKDGKIVVEKPGRI-----VPGVIGLMRALTINDAD 7962
>X62515-1|CAA44373.1| 4393|Homo sapiens Human basement membrane
heparan sulfate proteoglycan core protein protein.
Length = 4393
Score = 140 bits (339), Expect = 3e-32
Identities = 150/515 (29%), Positives = 211/515 (40%), Gaps = 61/515 (11%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + + ++TV ATL C A GSP+ I W K + HR L L R
Sbjct: 3213 APQVQAEEAELTVEAGHTATLRCSATGSPARTIHWSKLRSPLPWQ-HR--LEGDTLIIPR 3269
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D+G Y C AT+ G A + LHV + PE G+TV L+CL
Sbjct: 3270 VAQ----QDSGQYICNATSPAGHAEA-TIILHVESPPYATTV-PEHASVQAGETVQLQCL 3323
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G+P W + G +L +R L L + A D+GRY+C N G+ E
Sbjct: 3324 A-HGTPPLTFQWSRVGSSLPGRATARNEL-----LHFERAAPEDSGRYRCRVTNKVGSAE 3377
Query: 191 SAIATLKIHIKPYLITG--------------PEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
A A L + P + P+ G+SV F C V D + W
Sbjct: 3378 -AFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWF 3436
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-- 294
+ GG +P G + DG LR+ N+ + +G Y C+A G AS L + PS
Sbjct: 3437 KE--GGQLPPGHS--VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQASAQLVIQALPSVL 3492
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
IN+ + V G+ F C A G P+P + WS G + PG+ + V
Sbjct: 3493 INIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGH--LRPGIVQSG-------GVVR 3543
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
+ + D R C+A N AG++ L V + P I + P +P S
Sbjct: 3544 IAHVELADAGQYR----CTATNAAGTTQSHVLLLVQA----LPQI--SMPQEVRVPAGSA 3593
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
AVFPC A P P I+W +L + R + L+L + D+GTY C A++R G
Sbjct: 3594 AVFPCIASGYPTPDISWSKLDGSLPPDSR---LENNMLMLPSVQPQDAGTYVCTATNRQG 3650
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTK 509
K L V + P +F S LP P K
Sbjct: 3651 KVKAFAHLQVPERVVP---YFTQTPYSFLPLPTIK 3682
Score = 126 bits (305), Expect = 4e-28
Identities = 123/488 (25%), Positives = 192/488 (39%), Gaps = 35/488 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+P I P TV + Q A+ C +P ++ W + + H I P G + +
Sbjct: 3023 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVH--ISPNGSIITI 3080
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQ-GDTVVL 127
T H G Y C A+N+YG A+S N ++H + PE + G V L
Sbjct: 3081 VGTRPSNH---GTYRCVASNAYGVAQSVVNLSVHGP---PTVSVLPEGPVWVKVGKAVTL 3134
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAA 186
EC+ G P + W + T L+D ++ I A+ +DAG Y C+A+NA
Sbjct: 3135 ECVSA-GEPRSSARWTRISSTPAKLEQRTYGLMDSHTVLQISSAKPSDAGTYVCLAQNAL 3193
Query: 187 GTRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
GT + + + P + ++ + G + T +C G P + W +
Sbjct: 3194 GTAQKQVEVIVDTGAMAPGAPQVQAEEAELTVEAGHTATLRCSATGSPARTIHWSKLRS- 3252
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
PL L+ +L + V D G+Y C A + G A+ L V PP P
Sbjct: 3253 ---PLPWQHRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEH 3309
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+V++G + C A G P T WS G+ PG + + + F+ D+
Sbjct: 3310 ASVQAGETVQLQCLAHGTPPLTFQWSRVGSS---LPGRATAR-NELLHFERAAP---EDS 3362
Query: 362 DKNDSRNTIVCSAVNYAGSSFVR---GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
+ R T + V+ G L TS P + P +T I + F
Sbjct: 3363 GRYRCRVTNKVGSAEAFAQLLVQGPPGSLPATSIPAGSTPTVQVTPQLETKSIGASVEFH 3422
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVW 478
C + W+ EG L H DG L +++LD+S GTY C A GK
Sbjct: 3423 CAVPSDRGTQLRWFKEGGQLPPGHS---VQDGVLRIQNLDQSCQGTYICQAHGPWGKAQA 3479
Query: 479 SGALLVDS 486
S L++ +
Sbjct: 3480 SAQLVIQA 3487
Score = 111 bits (266), Expect = 2e-23
Identities = 106/408 (25%), Positives = 158/408 (38%), Gaps = 33/408 (8%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRG 134
SDAGVY C N + + SR L + + E ++S G V C
Sbjct: 1741 SDAGVYICTCRNLHRSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSK 1800
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
SP + W T L +G +D G L I++ + +DAG Y C N +
Sbjct: 1801 SPAYTLVW-----TRLHNGKLPTRAMDFNGILTIRNVQLSDAGTYVCTGSNMF-AMDQGT 1854
Query: 194 ATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
ATL + P + P + Q G F+C G P P + W GG +P +
Sbjct: 1855 ATLHVQASGTLSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-TGGPGGQLP-AK 1912
Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY--DPPSINLSPNSVNVES 306
++ G LRL V D+ +Y C A +S G A L V+ P + +SP V +
Sbjct: 1913 AQI-HGGILRLPAVEPTDQAQYLCRAHSSAGQQVARAVLHVHGGGGPRVQVSPERTQVHA 1971
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G R C A G P T+ W EG P +R + A + + I D
Sbjct: 1972 GRTVRLYCRAAGVPSATITWRKEGGS---LPPQARSERTDIAT---LLIPAITTAD---- 2021
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
+C A + AG++ R ++ V S D P + S+ ++ C +
Sbjct: 2022 AGFYLCVATSPAGTAQARIQVVVLSASDASQPPVKIESSSPSVTEGQTLDLNCVVAGSAH 2081
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+ WY G +L H V + L L + +DSG Y C + G
Sbjct: 2082 AQVTWYRRGGSL--PHHTQV-HGSRLRLPQVSPADSGEYVCRVENGSG 2126
Score = 109 bits (261), Expect = 8e-23
Identities = 129/482 (26%), Positives = 183/482 (37%), Gaps = 52/482 (10%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + P +TV Q A C A GSP+P + W GG I GG+ L
Sbjct: 1867 APVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEW-TGGPGGQLPAKAQI--HGGILRLP 1923
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLEC 129
A +D Y C A +S G +R A LHV ++ PE Q G TV L C
Sbjct: 1924 AVE---PTDQAQYLCRAHSSAGQQVAR-AVLHVHGGGGPRVQVSPERTQVHAGRTVRLYC 1979
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
G P + W+K G +L +R D L+I DAG Y C+A + AGT
Sbjct: 1980 -RAAGVPSATITWRKEGGSL--PPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTA 2036
Query: 190 ESAIATLKIHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
++ I + + P I V + G ++ C V G V W R GG++
Sbjct: 2037 QARIQVVVLSASDASQPPVKIESSSPSVTE-GQTLDLNCVVAGSAHAQVTWYRR--GGSL 2093
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV----YDPPS------ 294
P + LRL V AD GEY C EN G AS ++V + PS
Sbjct: 2094 P--HHTQVHGSRLRLPQVSPADSGEYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPG 2151
Query: 295 ----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
I + P+S +V G C G+ + W G P +R + H
Sbjct: 2152 STRPIRIEPSSSHVAEGQTLDLNCVVPGQAHAQVTWHKRGGS---LP--ARHQTHG---- 2202
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTL 409
++L ++ DS VC V +G +T+ S P P + S+ T+
Sbjct: 2203 ---SLLRLHQVTPADS-GEYVCHVVGTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTV 2258
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
C + WY G +L H+ L + +D+G Y C A
Sbjct: 2259 AEGQTLDLSCVVAGQAHAQVTWYKRGGSLPARHQ---VRGSRLYIFQASPADAGQYVCRA 2315
Query: 470 SS 471
S+
Sbjct: 2316 SN 2317
Score = 102 bits (245), Expect = 7e-21
Identities = 125/496 (25%), Positives = 192/496 (38%), Gaps = 64/496 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V G P + + TVA Q L+C G + WYK G + + R +
Sbjct: 2241 VIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRGGSLPA---RHQVRGSR 2297
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-------LHVAVLREEFRLEPESKQ 118
L+ +A+ +DAG Y C A+N + + T + A + R+EP S Q
Sbjct: 2298 LYIFQASP----ADAGQYVCRASNGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQ 2353
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY 178
A+G T+ L C+ P G V W K G +L H G L + A D+G Y
Sbjct: 2354 VAEGQTLDLNCVVP-GQSHAQVTWHKRGGSL-----PVRHQTHGSLLRLYQASPADSGEY 2407
Query: 179 QC-IARNAAGTRESAIATLK-------IHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDP 229
C + ++ S + T++ + + P + I VA+ G ++ C V G
Sbjct: 2408 VCRVLGSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAE-GQTLDLNCLVAGQA 2466
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
V W + GG++P R +V LRL V AD GEY C S G AS +T+
Sbjct: 2467 HAQVTWHKR--GGSLP-ARHQV-HGSRLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTI 2522
Query: 290 YDPPS----------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
S + + +S ++ +G+ C + T+ W G
Sbjct: 2523 QQRLSGSHSQGVAYPVRIESSSASLANGHTLDLNCLVASQAPHTITWYKRGG-------- 2574
Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV----TSDDDR 395
S H V + + + D + VC N AGS +T+ +S R
Sbjct: 2575 SLPSRH-QIVGSRLRIPQVTPADSGE----YVCHVSNGAGSRETSLIVTIQGSGSSHVPR 2629
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK 455
P I S+ T+ C P+ II WY G +L H+ T+ L L
Sbjct: 2630 VSPPIRIESSSPTVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQ---THGSHLRLH 2686
Query: 456 DLDKSDSGTYTCVASS 471
+ +DSG Y C A++
Sbjct: 2687 QMSVADSGEYVCRANN 2702
Score = 98.3 bits (234), Expect = 1e-19
Identities = 97/365 (26%), Positives = 149/365 (40%), Gaps = 33/365 (9%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG + L C P YW + + G + H G L + +DAG Y C
Sbjct: 1692 QGGSHSLRCQVSGRGPH-YFYWSREDGRPVPSGTQQRH--QGSELHFPSVQPSDAGVYIC 1748
Query: 181 IARNA--AGTRESAIATLKIHIKPYLITGPED--VVAQTGSSVTFQCRVGG-DPLPDVLW 235
RN + T + + + KP +T E + G+ VTF C P ++W
Sbjct: 1749 TCRNLHRSNTSRAELLVTEAPSKPITVTVEEQRSQSVRPGADVTFICTAKSKSPAYTLVW 1808
Query: 236 RRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---- 290
R G +P + +D +G L + NV L+D G Y C N + L V
Sbjct: 1809 TR-LHNGKLP---TRAMDFNGILTIRNVQLSDAGTYVCTGSNMFAMDQGTATLHVQASGT 1864
Query: 291 -DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P +++ P + V+ G +A F C+ATG P PT+ W+ G PG + A A
Sbjct: 1865 LSAPVVSIHPPQLTVQPGQLAEFRCSATGSPTPTLEWT--GG-----PG---GQLPAKAQ 1914
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
G +L + + D +C A + AG R L V P + + Q
Sbjct: 1915 IHG-GILRLPAVEPTDQAQ-YLCRAHSSAGQQVARAVLHVHGGGG--PRVQVSPERTQVH 1970
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+++ ++ C A P I W EG +L R T+ TL++ + +D+G Y CVA
Sbjct: 1971 AGRTVRLY-CRAAGVPSATITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVA 2029
Query: 470 SSRHG 474
+S G
Sbjct: 2030 TSPAG 2034
Score = 97.9 bits (233), Expect = 2e-19
Identities = 126/512 (24%), Positives = 194/512 (37%), Gaps = 60/512 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + + VA Q LNC G + W+K G + + R + L
Sbjct: 2436 GVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTWHKRGGSLPA---RHQVHGSRLRL 2492
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARS--------RNATLHVAVLREEFRLEPESKQSA 120
L+ T +D+G Y C S GT + R + H + R+E S A
Sbjct: 2493 LQVTP----ADSGEYVCRVVGSSGTQEASVLVTIQQRLSGSHSQGVAYPVRIESSSASLA 2548
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T+ L CL +P + W K G +L SR H + G L I D+G Y C
Sbjct: 2549 NGHTLDLNCLVASQAPH-TITWYKRGGSL----PSR-HQIVGSRLRIPQVTPADSGEYVC 2602
Query: 181 IARNAAGTRE-SAIATLK----IHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
N AG+RE S I T++ H+ P I V + G ++ C V P
Sbjct: 2603 HVSNGAGSRETSLIVTIQGSGSSHVPRVSPPIRIESSSPTVVE-GQTLDLNCVVARQPQA 2661
Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV-- 289
+ W + GG++P R + LRL + +AD GEY C A N++ A+ AS ++V
Sbjct: 2662 IITWYKR--GGSLP-SRHQT-HGSHLRLHQMSVADSGEYVCRANNNIDALEASIVISVSP 2717
Query: 290 -YDPPS-------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF---PG 338
PS I + +S +V G C G+ + W G + G
Sbjct: 2718 SAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSLPSYHQTRG 2777
Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
+H + G V + + + +V + +GSS V + R P
Sbjct: 2778 SRLRLHHVSPADSGEYVCRVMGSSGPLEASVLV--TIEASGSSAVHVPAPGGAPPIRIEP 2835
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLD 458
+ QTL +K C + W+ G L H+ + L L +
Sbjct: 2836 SSSRVAEGQTLDLK------CVVPGQAHAQVTWHKRGGNLPARHQ---VHGPLLRLNQVS 2886
Query: 459 KSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+DSG Y+C + G + + L+ P +P
Sbjct: 2887 PADSGEYSCQVTGSSGT-LEASVLVTIEPSSP 2917
Score = 94.3 bits (224), Expect = 2e-18
Identities = 129/495 (26%), Positives = 186/495 (37%), Gaps = 78/495 (15%)
Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS--DTHRSILPAGGLFFLRATHGRVHSD 79
TV Q LNC P I WYK G + S TH S L H +D
Sbjct: 2642 TVVEGQTLDLNCVVARQPQAIITWYKRGGSLPSRHQTHGSHL---------RLHQMSVAD 2692
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREE---------FRLEPESKQSAQGDTVVLECL 130
+G Y C A N+ A + + V+ R+E S A+G+T+ L C+
Sbjct: 2693 SGEYVCRANNNID-ALEASIVISVSPSAGSPSAPGSSMPIRIESSSSHVAEGETLDLNCV 2751
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
P G V W K G +L H G L + D+G Y C ++G E
Sbjct: 2752 VP-GQAHAQVTWHKRGGSL-----PSYHQTRGSRLRLHHVSPADSGEYVCRVMGSSGPLE 2805
Query: 191 -SAIATLK------IHIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
S + T++ +H+ P + P G ++ +C V G V W +
Sbjct: 2806 ASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHAQVTWHKR 2865
Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS---- 294
GGN+P R +V LRL+ V AD GEYSC+ S G + AS +T+ +P S
Sbjct: 2866 --GGNLP-ARHQV-HGPLLRLNQVSPADSGEYSCQVTGSSGTLEASVLVTI-EPSSPGPI 2920
Query: 295 --------INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
I + +S +V G C G+ + W G P +R + H
Sbjct: 2921 PAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKRGGS---LP--ARHQTHG 2975
Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT------SDDDRPPPII 400
+ L ++ DS VC A G TVT S P+I
Sbjct: 2976 SQ-------LRLHHVSPADS-GEYVCRAAGGPGPE-QEASFTVTVPPSEGSSYRLRSPVI 3026
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459
+ P + T+ A F C PI + W + L N + N + +
Sbjct: 3027 SIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQELEDNVHIS-PNGSIITIVGTRP 3085
Query: 460 SDSGTYTCVASSRHG 474
S+ GTY CVAS+ +G
Sbjct: 3086 SNHGTYRCVASNAYG 3100
Score = 93.9 bits (223), Expect = 3e-18
Identities = 90/350 (25%), Positives = 137/350 (39%), Gaps = 40/350 (11%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
+V G P + P V + L CRA G PS I W K G +
Sbjct: 1951 HVHGGGGPRVQVSPERTQVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTDIA 2010
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA---VLREEFRLEPESKQSAQ 121
L T +DAG Y C AT+ GTA++R + ++ + ++E S +
Sbjct: 2011 TLLIPAIT----TADAGFYLCVATSPAGTAQARIQVVVLSASDASQPPVKIESSSPSVTE 2066
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G T+ L C+ GS V W + G +L +++H G L + D+G Y C
Sbjct: 2067 GQTLDLNCV-VAGSAHAQVTWYRRGGSL--PHHTQVH---GSRLRLPQVSPADSGEYVCR 2120
Query: 182 ARNAAGTRESAIATLKIH--------------IKPYLITGPEDVVAQTGSSVTFQCRVGG 227
N +G +E++I +H +P I VA+ G ++ C V G
Sbjct: 2121 VENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAE-GQTLDLNCVVPG 2179
Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGY 286
V W + GG++P + GS LRL V AD GEY C + G + AS
Sbjct: 2180 QAHAQVTWHKR--GGSLP---ARHQTHGSLLRLHQVTPADSGEYVCHVVGTSGPLEASVL 2234
Query: 287 LTVYDP------PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
+T+ P + + +S V G +C G+ + W G
Sbjct: 2235 VTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKRG 2284
Score = 93.9 bits (223), Expect = 3e-18
Identities = 82/286 (28%), Positives = 120/286 (41%), Gaps = 23/286 (8%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAG 64
+ +G P + P T + +C +RW+K GG L + +
Sbjct: 3396 IPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQLPPGHSVQD----- 3450
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G+ ++ S G Y C+A +G A++ + A+ + + G
Sbjct: 3451 GVLRIQNLD---QSCQGTYICQAHGPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHA 3507
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIAR 183
V ECL G P+P V W K G G R +V G +V I DAG+Y+C A
Sbjct: 3508 VEFECLA-LGDPKPQVTWSKVG------GHLRPGIVQSGGVVRIAHVELADAGQYRCTAT 3560
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
NAAGT +S + L + P I+ P++V GS+ F C G P PD+ W + G
Sbjct: 3561 NAAGTTQSHVLLL-VQALPQ-ISMPQEVRVPAGSAAVFPCIASGYPTPDISWSK-LDGSL 3617
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
P R L++ L L +V D G Y C A N G V A +L V
Sbjct: 3618 PPDSR---LENNMLMLPSVQPQDAGTYVCTATNRQGKVKAFAHLQV 3660
Score = 83.4 bits (197), Expect = 4e-15
Identities = 118/500 (23%), Positives = 181/500 (36%), Gaps = 69/500 (13%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA + LNC G + W+K G + S H++ G L H +D+G
Sbjct: 2740 VAEGETLDLNCVVPGQAHAQVTWHKRGGSLPS-YHQT---RGSRLRL---HHVSPADSGE 2792
Query: 83 YWCEATNSYGTAR---------SRNATLHVAVL--REEFRLEPESKQSAQGDTVVLECLP 131
Y C S G S ++ +HV R+EP S + A+G T+ L+C+
Sbjct: 2793 YVCRVMGSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVV 2852
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
P G V W K G L H V G L + D+G Y C ++GT E+
Sbjct: 2853 P-GQAHAQVTWHKRGGNL-----PARHQVHGPLLRLNQVSPADSGEYSCQVTGSSGTLEA 2906
Query: 192 AIATLKIHIKPYLITGP---EDVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGG 241
++ P I P + + + SS + C V G V W + G
Sbjct: 2907 SVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQVTWYKR--G 2964
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP--------- 292
G++P LRL +V AD GEY C A G + + P
Sbjct: 2965 GSLPARHQT--HGSQLRLHHVSPADSGEYVCRAAGGPGPEQEASFTVTVPPSEGSSYRLR 3022
Query: 293 -PSINLSPNSVNVESGNVARFTCTATGRPEP-TMFWSVEGNRTIIFPGMSRDKYHATAVF 350
P I++ P S V+ G A F C P ++ W D H +
Sbjct: 3023 SPVISIDPPSSTVQQGQDASFKCLIHDGAAPISLEWKTRNQEL-------EDNVH---IS 3072
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-L 409
+++TI T + + T C A N G + L+V PP ++ P +
Sbjct: 3073 PNGSIITIVGT-RPSNHGTYRCVASNAYGVAQSVVNLSV-----HGPPTVSVLPEGPVWV 3126
Query: 410 PIKSMAVFPCTAICTPEPIIAW--YFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYT 466
+ C + P W A ++ + + T L + SD+GTY
Sbjct: 3127 KVGKAVTLECVSAGEPRSSARWTRISSTPAKLEQRTYGLMDSHTVLQISSAKPSDAGTYV 3186
Query: 467 CVASSRHGKYVWSGALLVDS 486
C+A + G ++VD+
Sbjct: 3187 CLAQNALGTAQKQVEVIVDT 3206
Score = 46.4 bits (105), Expect = 6e-04
Identities = 36/118 (30%), Positives = 52/118 (44%), Gaps = 10/118 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAV-FPCTAICTPEP-IIAWYFEGEALIQNHRRNVTNDG---T 451
PP + P + V F C AI P P +I W + R VT++G T
Sbjct: 405 PPQVVTPPRESIQASRGQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTVTSEGGRGT 464
Query: 452 LVLKDLDKSDSGTYTCVASSRHGKY--VWSGAL-LVDSPIN--PNIHFFRAADVSSLP 504
L+++D+ +SD G YTC A + G + G L LV P+ HF+ + LP
Sbjct: 465 LIIRDVKESDQGAYTCEAMNARGMVFGIPDGVLELVPQRAGPCPDGHFYLEHSAACLP 522
Score = 45.2 bits (102), Expect = 0.001
Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 8/86 (9%)
Query: 202 PYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVL-WRRSAGGGNMPLG-RVKVLDDG--- 255
P ++T P E + A G +VTF C G P P ++ WR + G++P RV V +G
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPAPFLINWRLN--WGHIPSQPRVTVTSEGGRG 463
Query: 256 SLRLDNVILADEGEYSCEAENSVGAV 281
+L + +V +D+G Y+CEA N+ G V
Sbjct: 464 TLIIRDVKESDQGAYTCEAMNARGMV 489
Score = 44.0 bits (99), Expect = 0.003
Identities = 39/181 (21%), Positives = 72/181 (39%), Gaps = 13/181 (7%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P + + P V G C +GR +WS E R + P ++ ++ +
Sbjct: 1678 PLVVEVHPARSIVPQGGSHSLRCQVSGRGPHYFYWSREDGRPV--PSGTQQRHQGSE--- 1732
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L +D+ +C+ N S+ R +L VT +P + +Q++
Sbjct: 1733 ----LHFPSVQPSDA-GVYICTCRNLHRSNTSRAELLVTEAPSKPITVTVEEQRSQSVRP 1787
Query: 412 KSMAVFPCTAIC-TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
+ F CTA +P + W + R + +G L ++++ SD+GTY C S
Sbjct: 1788 GADVTFICTAKSKSPAYTLVWTRLHNGKLPT--RAMDFNGILTIRNVQLSDAGTYVCTGS 1845
Query: 471 S 471
+
Sbjct: 1846 N 1846
Score = 38.7 bits (86), Expect = 0.13
Identities = 25/75 (33%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPN-VYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQ 172
ES Q+++G TV C+ G P P + W+ N + + G G L+I+D ++
Sbjct: 414 ESIQASRGQTVTFTCVAI-GVPAPFLINWRLNWGHIPSQPRVTVTSEGGRGTLIIRDVKE 472
Query: 173 TDAGRYQCIARNAAG 187
+D G Y C A NA G
Sbjct: 473 SDQGAYTCEAMNARG 487
Score = 35.5 bits (78), Expect = 1.2
Identities = 25/83 (30%), Positives = 36/83 (43%), Gaps = 3/83 (3%)
Query: 12 PYIIEQPLD-VTVARHQPATLNCRAGGSPSP-AIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P ++ P + + +R Q T C A G P+P I W + S ++ GG L
Sbjct: 406 PQVVTPPRESIQASRGQTVTFTCVAIGVPAPFLINWRLNWGHIPSQPRVTVTSEGGRGTL 465
Query: 70 RATHGRVHSDAGVYWCEATNSYG 92
+ SD G Y CEA N+ G
Sbjct: 466 IIRDVK-ESDQGAYTCEAMNARG 487
>X59847-1|CAA42508.1| 1257|Homo sapiens Neural cell adhesion
molecule L1 protein.
Length = 1257
Score = 136 bits (329), Expect = 5e-31
Identities = 132/484 (27%), Positives = 199/484 (41%), Gaps = 37/484 (7%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAG 64
E P I EQ P + V +L C A G P RW + GV + P
Sbjct: 33 EPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHS 92
Query: 65 GLFFLRATHGR-VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
G F + + G+Y C A+N GTA S L + + + + +G+
Sbjct: 93 GSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 152
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQC-- 180
+VVL C PP + +YW N + L D R+ + GNL + +D Y C
Sbjct: 153 SVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA 211
Query: 181 --------IARNAAGTRESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDP 229
I + R A ++ I KP L+ +VA G + +C G P
Sbjct: 212 HFPGIRTIIQKEPIDLRVKATNSM-IDRKPRLLFPTNSSTHLVALQGQPLVLECIAEGFP 270
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
P + R +G MP RV + +L+L V D+GEY C AENS+G+ + Y+T
Sbjct: 271 TPTIKSVRPSGP--MPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 328
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
V P P S G AR C GRP+P + W + G I +++D+ +
Sbjct: 329 VEAAPYWLHKPQSHLYGPGETARLDCQVEGRPQPEVTWRING---IPVEELAKDQKY--R 383
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
+ G +L ++ +D+ T C A N G + V P I+T
Sbjct: 384 IQRGALIL--SNVQPSDTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYM 437
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
S A C A P P + W E G ++Q+ R +GTL ++DL +D+G Y C
Sbjct: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 497
Query: 468 VASS 471
+A++
Sbjct: 498 LAAN 501
Score = 121 bits (292), Expect = 1e-26
Identities = 135/496 (27%), Positives = 204/496 (41%), Gaps = 55/496 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + K + D + L + + D G Y+C
Sbjct: 256 QGQPLVLECIA-EGFPTPTI--KSVRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRC 312
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 313 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVEGRPQPEVTWRINGI 371
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 372 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 431
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 432 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 483
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 484 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 537
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 538 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 597
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H VT + V +SWS
Sbjct: 598 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLVTQSQVRVSWSPAED- 640
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 641 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 691
Query: 590 ENSHGLSGPSPVSDSV 605
N +G PSPVS++V
Sbjct: 692 INKYGPGEPSPVSETV 707
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 326 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVEGRPQPEVTWRINGIPVEELAKDQKYRIQ 385
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 386 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 440
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 441 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 497
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 498 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 555
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 556 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 612
Score = 101 bits (242), Expect = 2e-20
Identities = 96/346 (27%), Positives = 147/346 (42%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+ + + +D L L+ D G Y C
Sbjct: 258 QPLVLECIAEGFPTPTIKSVRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 313
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C G P+P V W+ N
Sbjct: 314 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVEGRPQPEVTWRIN 369
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 370 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 429
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 430 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 489
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 490 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 549
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 550 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 588
Score = 40.7 bits (91), Expect = 0.031
Identities = 33/135 (24%), Positives = 57/135 (42%), Gaps = 6/135 (4%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+++ + YE + + +G + + +D P P + ILN++ V +KW
Sbjct: 775 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 834
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-----QATSLIMTNLTSGVSYSV 808
P +L G + GYNV W + K H TS+I++ L SY +
Sbjct: 835 PVDLAQVKGHLRGYNVTY-WREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 893
Query: 809 QIAAETIIGLGPFSQ 823
++ A G GP S+
Sbjct: 894 EVQAFNGRGSGPASE 908
>BC115736-1|AAI15737.1| 1192|Homo sapiens NRCAM protein protein.
Length = 1192
Score = 135 bits (327), Expect = 8e-31
Identities = 128/487 (26%), Positives = 209/487 (42%), Gaps = 39/487 (8%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
+ P I +Q P D + + + C A G P P+ W + G + D ++ P G
Sbjct: 44 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103
Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
+ + G+ + GVY C A N G A S N + + L + +LEP + QS G
Sbjct: 104 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 161
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
++VL C PP G P P ++W N L + R+ G+L + D Y C A
Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 220
Query: 183 R-NAAGT--RESAIATLKIHIK-----PYLITGPEDVVAQT----GSSVTFQCRVGGDPL 230
R N T ++ I+ I K P PE + G+ ++ +C G P
Sbjct: 221 RFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 280
Query: 231 PDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
P + W + G +P R + + +L++ +V AD G Y C A+N++GA+ + + V
Sbjct: 281 PIIYWAKE--DGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV 338
Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P +P ++ + G C A G P+P + W G I P K
Sbjct: 339 KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK------ 392
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
DG T++ N +++ + C+A N G + V ++ PP I+T + +
Sbjct: 393 IDGDTIIFSNVQERSSA--VYQCNASNEYGYLLANAFVNVLAE---PPRILTPANTLYQV 447
Query: 410 PIKSMAVFPCTAICTPEPIIAWY--FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
A+ C +P P I W+ +G AL ++ + +GTL + K +GTYTC
Sbjct: 448 IANRPALLDCAFFGSPLPTIEWFKGAKGSALHED-IYVLHENGTLEIPVAQKDSTGTYTC 506
Query: 468 VASSRHG 474
VA ++ G
Sbjct: 507 VARNKLG 513
Score = 131 bits (317), Expect = 1e-29
Identities = 165/621 (26%), Positives = 241/621 (38%), Gaps = 64/621 (10%)
Query: 6 VTSGEAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA 63
V +P ++ L+ +T+ Q L CR G P P I W + + R
Sbjct: 139 VRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGL 198
Query: 64 GG-LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL-------REEFRLEPE 115
G L+F D Y C A ++ + + V V+ R L PE
Sbjct: 199 NGDLYFSNVLPEDTRED---YICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPE 255
Query: 116 ----SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
+K+ +G+ + LEC+ G P P +YW K L + ++ L I
Sbjct: 256 GNASNKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVS 312
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
+ D+G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P
Sbjct: 313 EADSGNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKP 371
Query: 232 DVLWRRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
+ W + + P + +D ++ NV Y C A N G + A+ ++ V
Sbjct: 372 RISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVL 431
Query: 291 -DPPSINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
+PP I N++ V + A C G P PT+ W F G H
Sbjct: 432 AEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDI 482
Query: 349 -VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
V L I K DS T C A N G + L + + I P
Sbjct: 483 YVLHENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDATWIVKQPEYA 536
Query: 408 TLPIKSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ SM F C T + W + L + R V D LV+ D+ DSGTY
Sbjct: 537 VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTY 595
Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
TCVA++ S L V +P P A V +P PP + D SV LSW+
Sbjct: 596 TCVANTTLDSVSASAVLSVVAP-TPT-----PAPVYDVPNPPFDLELTDQLDKSVQLSWT 649
Query: 526 ---QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGIT 582
NN + I+ Y+ + + L + T + QT +K L P +
Sbjct: 650 PGDDNNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVN 697
Query: 583 YMFIVRTENSHGLSGPSPVSD 603
Y F V NS G S PS S+
Sbjct: 698 YSFRVMAVNSIGKSLPSEASE 718
>BC114570-1|AAI14571.1| 1180|Homo sapiens NRCAM protein protein.
Length = 1180
Score = 135 bits (327), Expect = 8e-31
Identities = 128/487 (26%), Positives = 209/487 (42%), Gaps = 39/487 (8%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
+ P I +Q P D + + + C A G P P+ W + G + D ++ P G
Sbjct: 44 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103
Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
+ + G+ + GVY C A N G A S N + + L + +LEP + QS G
Sbjct: 104 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 161
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
++VL C PP G P P ++W N L + R+ G+L + D Y C A
Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 220
Query: 183 R-NAAGT--RESAIATLKIHIK-----PYLITGPEDVVAQT----GSSVTFQCRVGGDPL 230
R N T ++ I+ I K P PE + G+ ++ +C G P
Sbjct: 221 RFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 280
Query: 231 PDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
P + W + G +P R + + +L++ +V AD G Y C A+N++GA+ + + V
Sbjct: 281 PIIYWAKE--DGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV 338
Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P +P ++ + G C A G P+P + W G I P K
Sbjct: 339 KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK------ 392
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
DG T++ N +++ + C+A N G + V ++ PP I+T + +
Sbjct: 393 IDGDTIIFSNVQERSSA--VYQCNASNEYGYLLANAFVNVLAE---PPRILTPANTLYQV 447
Query: 410 PIKSMAVFPCTAICTPEPIIAWY--FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
A+ C +P P I W+ +G AL ++ + +GTL + K +GTYTC
Sbjct: 448 IANRPALLDCAFFGSPLPTIEWFKGAKGSALHED-IYVLHENGTLEIPVAQKDSTGTYTC 506
Query: 468 VASSRHG 474
VA ++ G
Sbjct: 507 VARNKLG 513
Score = 131 bits (317), Expect = 1e-29
Identities = 165/621 (26%), Positives = 241/621 (38%), Gaps = 64/621 (10%)
Query: 6 VTSGEAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA 63
V +P ++ L+ +T+ Q L CR G P P I W + + R
Sbjct: 139 VRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGL 198
Query: 64 GG-LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL-------REEFRLEPE 115
G L+F D Y C A ++ + + V V+ R L PE
Sbjct: 199 NGDLYFSNVLPEDTRED---YICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPE 255
Query: 116 ----SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
+K+ +G+ + LEC+ G P P +YW K L + ++ L I
Sbjct: 256 GNASNKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVS 312
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
+ D+G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P
Sbjct: 313 EADSGNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKP 371
Query: 232 DVLWRRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
+ W + + P + +D ++ NV Y C A N G + A+ ++ V
Sbjct: 372 RISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVL 431
Query: 291 -DPPSINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
+PP I N++ V + A C G P PT+ W F G H
Sbjct: 432 AEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDI 482
Query: 349 -VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
V L I K DS T C A N G + L + + I P
Sbjct: 483 YVLHENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDATWIVKQPEYA 536
Query: 408 TLPIKSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ SM F C T + W + L + R V D LV+ D+ DSGTY
Sbjct: 537 VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTY 595
Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
TCVA++ S L V +P P A V +P PP + D SV LSW+
Sbjct: 596 TCVANTTLDSVSASAVLSVVAP-TPT-----PAPVYDVPNPPFDLELTDQLDKSVQLSWT 649
Query: 526 ---QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGIT 582
NN + I+ Y+ + + L + T + QT +K L P +
Sbjct: 650 PGDDNNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVN 697
Query: 583 YMFIVRTENSHGLSGPSPVSD 603
Y F V NS G S PS S+
Sbjct: 698 YSFRVMAVNSIGKSLPSEASE 718
>AB002341-1|BAA20801.2| 1187|Homo sapiens KIAA0343 protein.
Length = 1187
Score = 135 bits (327), Expect = 8e-31
Identities = 128/487 (26%), Positives = 209/487 (42%), Gaps = 39/487 (8%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
+ P I +Q P D + + + C A G P P+ W + G + D ++ P G
Sbjct: 51 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 110
Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
+ + G+ + GVY C A N G A S N + + L + +LEP + QS G
Sbjct: 111 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 168
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
++VL C PP G P P ++W N L + R+ G+L + D Y C A
Sbjct: 169 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 227
Query: 183 R-NAAGT--RESAIATLKIHIK-----PYLITGPEDVVAQT----GSSVTFQCRVGGDPL 230
R N T ++ I+ I K P PE + G+ ++ +C G P
Sbjct: 228 RFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPT 287
Query: 231 PDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
P + W + G +P R + + +L++ +V AD G Y C A+N++GA+ + + V
Sbjct: 288 PIIYWAKE--DGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRV 345
Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P +P ++ + G C A G P+P + W G I P K
Sbjct: 346 KAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRK------ 399
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL 409
DG T++ N +++ + C+A N G + V ++ PP I+T + +
Sbjct: 400 IDGDTIIFSNVQERSSA--VYQCNASNEYGYLLANAFVNVLAE---PPRILTPANTLYQV 454
Query: 410 PIKSMAVFPCTAICTPEPIIAWY--FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
A+ C +P P I W+ +G AL ++ + +GTL + K +GTYTC
Sbjct: 455 IANRPALLDCAFFGSPLPTIEWFKGAKGSALHED-IYVLHENGTLEIPVAQKDSTGTYTC 513
Query: 468 VASSRHG 474
VA ++ G
Sbjct: 514 VARNKLG 520
Score = 130 bits (313), Expect = 4e-29
Identities = 164/621 (26%), Positives = 240/621 (38%), Gaps = 64/621 (10%)
Query: 6 VTSGEAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA 63
V +P ++ L+ +T+ Q L CR G P P I W + + R
Sbjct: 146 VRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGL 205
Query: 64 GG-LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL-------REEFRLEPE 115
G L+F D Y C A ++ + + V V+ R L PE
Sbjct: 206 NGDLYFSNVLPEDTRED---YICYARFNHTQTIQQKQPISVKVISAKSSRERPPTFLTPE 262
Query: 116 ----SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
+K+ +G+ + LEC+ G P P +YW K L + ++ L I
Sbjct: 263 GNASNKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVS 319
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
+ D+G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P
Sbjct: 320 EADSGNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKP 378
Query: 232 DVLWRRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
+ W + + P + +D ++ NV Y C A N G + A+ ++ V
Sbjct: 379 RISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVL 438
Query: 291 -DPPSINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
+PP I N++ V + A C G P PT+ W F G H
Sbjct: 439 AEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDI 489
Query: 349 -VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
V L I K DS T C A N G + L + + I P
Sbjct: 490 YVLHENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDATWIVKQPEYA 543
Query: 408 TLPIKSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY 465
+ SM F C T + W + L + R V D LV+ D+ DSGTY
Sbjct: 544 VVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTY 602
Query: 466 TCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
TCVA++ S L V +P P A V +P PP + D SV LSW+
Sbjct: 603 TCVANTTLDSVSASAVLSVVAP-TPT-----PAPVYDVPNPPFDLELTDQLDKSVQLSWT 656
Query: 526 ---QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGIT 582
NN + I+ Y+ + + L + T G A+ +L P +
Sbjct: 657 PGDDNNSPITKFIIEYE-DAMHKPGLWHHQT--EVSGTQTTAQ---------LNLSPYVN 704
Query: 583 YMFIVRTENSHGLSGPSPVSD 603
Y F V NS G S PS S+
Sbjct: 705 YSFRVMAVNSIGKSLPSEASE 725
>BC117674-1|AAI17675.2| 1240|Homo sapiens NFASC protein protein.
Length = 1240
Score = 133 bits (322), Expect = 3e-30
Identities = 125/469 (26%), Positives = 202/469 (43%), Gaps = 44/469 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87
+ C A G+P+P+ W + + D S+ G + + GR G Y C A
Sbjct: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
Query: 88 TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
N +GTA S L V+ L + L+P Q +G + L+C PP G P P ++W +
Sbjct: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 178
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR-NAAGT-RESAIATLKI---- 198
+ D R+ G+L + D Y C AR + T ++ TLK+
Sbjct: 179 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTR 237
Query: 199 ---HIKPYLI----TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + T +V + G + +C G P PD+ W + GG++P + K
Sbjct: 238 GVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKF 294
Query: 252 LD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
+ + +LR+ NV D GEY C A N +G++ + + V P P ++ + G
Sbjct: 295 ENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG 354
Query: 311 RFTCTATGRPEPTMFWSVEGN-RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
R C A G P+PT+ W V G P +R+ T +F DT + SR
Sbjct: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF--------RDT-QISSRAV 405
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEP 427
C+ N G ++V D PP +++ P NQ + + + C +P P
Sbjct: 406 YQCNTSNEHGYLLANAFVSVL---DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIP 460
Query: 428 IIAWYFEGE-ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W+ G+ + + +V +G+L +K + K D G YTCVA++ GK
Sbjct: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509
Score = 114 bits (275), Expect = 2e-24
Identities = 86/284 (30%), Positives = 134/284 (47%), Gaps = 15/284 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 336 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 393
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 394 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 448
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 449 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 506
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 507 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 565
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+G +D SL + V D+G Y+C A + A YLTV
Sbjct: 566 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Score = 113 bits (272), Expect = 4e-24
Identities = 159/620 (25%), Positives = 249/620 (40%), Gaps = 65/620 (10%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHR-SILPAGGL 66
++P ++ LD V V P TL C G PSP I W + ++ R S G L
Sbjct: 138 KSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDL 197
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYG-TARSRNA-TLHVAVLREEFR-----LEPESKQS 119
+F + +D Y C A + T + +N TL V R + P+ S
Sbjct: 198 YFSNVMLQDMQTD---YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 254
Query: 120 AQ----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+Q G ++LEC+ G P P++ W K G L D + L I + + D+
Sbjct: 255 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 311
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W
Sbjct: 312 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370
Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ P +V D + D I + Y C N G + A+ +++V D P
Sbjct: 371 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 429
Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
LSP + + V N R C G P PT+ W G + + G YH V++
Sbjct: 430 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 482
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
+ L I K D + C A N G + + +L V + P I P +Q
Sbjct: 483 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 535
Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+ C P + ++W + E L +R +D +L + + + D G+YTCVA
Sbjct: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 594
Query: 470 SSRHGKYVWSGAL--LVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTD---TSVTLS 523
S+ + + L L D N +++LP G P +P +TD SV L+
Sbjct: 595 STELDQDLAKAYLTVLADQATPTN-------RLAALPKGRPDRPRDLELTDLAERSVRLT 647
Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583
W + +S I Y V+ + G W ++ + V L P + Y
Sbjct: 648 WIPGD-ANNSPITDYVVQFEEDQFQPG--------VWHDHSKYPGSVNSAVLRLSPYVNY 698
Query: 584 MFIVRTENSHGLSGPSPVSD 603
F V N G S PS S+
Sbjct: 699 QFRVIAINEVGSSHPSLPSE 718
Score = 88.2 bits (209), Expect = 2e-16
Identities = 103/395 (26%), Positives = 157/395 (39%), Gaps = 44/395 (11%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
D +++EC +G+P P+ +W +N + D R+ + ++ D R + G
Sbjct: 57 DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 115
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235
YQC ARN GT S L++ P + + VV Q G+ +T QC G P P + W
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 175
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEAE-NSVGAVSASGYLTV---- 289
S+ RV +G L NV+L D + +YSC A + + T+
Sbjct: 176 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT 235
Query: 290 -----YDPPSINL---SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
PS + +S V G C A+G P P + W +G +
Sbjct: 236 TRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG------DLPS 289
Query: 342 DKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
DK A F+ L I + + DS C A N GS +R ++V + P
Sbjct: 290 DK----AKFENFNKALRITNVSEEDS-GEYFCLASNKMGS--IRHTISVRV---KAAPYW 339
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ---NHRRNVTNDGTLVLKDL 457
+ P N L C A P+P + W GE L N R V D T++ +D
Sbjct: 340 LDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDT 398
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
S Y C S+ HG Y+ + A + + P +
Sbjct: 399 QISSRAVYQCNTSNEHG-YLLANAFVSVLDVPPRM 432
Score = 62.9 bits (146), Expect = 7e-09
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 17/279 (6%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD----NV 262
+D + ++ +C G+P P W R++ N+ RV + G+L +D
Sbjct: 49 KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 108
Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTAT- 317
EGEY C A N G A+S L V P NL P V V+ G C
Sbjct: 109 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 166
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P P +FW I ++ F V +L TD + + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNV-MLQDMQTDYSCNARFHFTHTIQQ 225
Query: 378 AGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEG 435
+ F LT +R P + G ++ + ++ M + C A P P IAWY +G
Sbjct: 226 K-NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG 284
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
L + + + L + ++ + DSG Y C+AS++ G
Sbjct: 285 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 323
>AL391822-8|CAI14664.1| 1040|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1040
Score = 133 bits (322), Expect = 3e-30
Identities = 125/469 (26%), Positives = 202/469 (43%), Gaps = 44/469 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87
+ C A G+P+P+ W + + D S+ G + + GR G Y C A
Sbjct: 30 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 89
Query: 88 TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
N +GTA S L V+ L + L+P Q +G + L+C PP G P P ++W +
Sbjct: 90 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 147
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR-NAAGT-RESAIATLKI---- 198
+ D R+ G+L + D Y C AR + T ++ TLK+
Sbjct: 148 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTR 206
Query: 199 ---HIKPYLI----TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + T +V + G + +C G P PD+ W + GG++P + K
Sbjct: 207 GVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKF 263
Query: 252 LD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
+ + +LR+ NV D GEY C A N +G++ + + V P P ++ + G
Sbjct: 264 ENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG 323
Query: 311 RFTCTATGRPEPTMFWSVEGN-RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
R C A G P+PT+ W V G P +R+ T +F DT + SR
Sbjct: 324 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF--------RDT-QISSRAV 374
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEP 427
C+ N G ++V D PP +++ P NQ + + + C +P P
Sbjct: 375 YQCNTSNEHGYLLANAFVSVL---DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIP 429
Query: 428 IIAWYFEGE-ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W+ G+ + + +V +G+L +K + K D G YTCVA++ GK
Sbjct: 430 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 478
Score = 114 bits (275), Expect = 2e-24
Identities = 86/284 (30%), Positives = 134/284 (47%), Gaps = 15/284 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 305 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 362
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 363 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 417
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 418 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 475
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 476 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 534
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+G +D SL + V D+G Y+C A + A YLTV
Sbjct: 535 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 578
Score = 113 bits (272), Expect = 4e-24
Identities = 159/620 (25%), Positives = 249/620 (40%), Gaps = 65/620 (10%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHR-SILPAGGL 66
++P ++ LD V V P TL C G PSP I W + ++ R S G L
Sbjct: 107 KSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDL 166
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYG-TARSRNA-TLHVAVLREEFR-----LEPESKQS 119
+F + +D Y C A + T + +N TL V R + P+ S
Sbjct: 167 YFSNVMLQDMQTD---YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 223
Query: 120 AQ----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+Q G ++LEC+ G P P++ W K G L D + L I + + D+
Sbjct: 224 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 280
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W
Sbjct: 281 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 339
Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ P +V D + D I + Y C N G + A+ +++V D P
Sbjct: 340 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 398
Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
LSP + + V N R C G P PT+ W G + + G YH V++
Sbjct: 399 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 451
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
+ L I K D + C A N G + + +L V + P I P +Q
Sbjct: 452 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 504
Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+ C P + ++W + E L +R +D +L + + + D G+YTCVA
Sbjct: 505 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 563
Query: 470 SSRHGKYVWSGAL--LVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTD---TSVTLS 523
S+ + + L L D N +++LP G P +P +TD SV L+
Sbjct: 564 STELDQDLAKAYLTVLADQATPTN-------RLAALPKGRPDRPRDLELTDLAERSVRLT 616
Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583
W + +S I Y V+ + G W ++ + V L P + Y
Sbjct: 617 WIPGD-ANNSPITDYVVQFEEDQFQPG--------VWHDHSKYPGSVNSAVLRLSPYVNY 667
Query: 584 MFIVRTENSHGLSGPSPVSD 603
F V N G S PS S+
Sbjct: 668 QFRVIAINEVGSSHPSLPSE 687
Score = 88.2 bits (209), Expect = 2e-16
Identities = 103/395 (26%), Positives = 157/395 (39%), Gaps = 44/395 (11%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
D +++EC +G+P P+ +W +N + D R+ + ++ D R + G
Sbjct: 26 DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 84
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235
YQC ARN GT S L++ P + + VV Q G+ +T QC G P P + W
Sbjct: 85 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 144
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEAE-NSVGAVSASGYLTV---- 289
S+ RV +G L NV+L D + +YSC A + + T+
Sbjct: 145 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT 204
Query: 290 -----YDPPSINL---SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
PS + +S V G C A+G P P + W +G +
Sbjct: 205 TRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG------DLPS 258
Query: 342 DKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
DK A F+ L I + + DS C A N GS +R ++V + P
Sbjct: 259 DK----AKFENFNKALRITNVSEEDS-GEYFCLASNKMGS--IRHTISVRV---KAAPYW 308
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ---NHRRNVTNDGTLVLKDL 457
+ P N L C A P+P + W GE L N R V D T++ +D
Sbjct: 309 LDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDT 367
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
S Y C S+ HG Y+ + A + + P +
Sbjct: 368 QISSRAVYQCNTSNEHG-YLLANAFVSVLDVPPRM 401
Score = 62.9 bits (146), Expect = 7e-09
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 17/279 (6%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD----NV 262
+D + ++ +C G+P P W R++ N+ RV + G+L +D
Sbjct: 18 KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 77
Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTAT- 317
EGEY C A N G A+S L V P NL P V V+ G C
Sbjct: 78 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 135
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P P +FW I ++ F V +L TD + + +
Sbjct: 136 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNV-MLQDMQTDYSCNARFHFTHTIQQ 194
Query: 378 AGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEG 435
+ F LT +R P + G ++ + ++ M + C A P P IAWY +G
Sbjct: 195 K-NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG 253
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
L + + + L + ++ + DSG Y C+AS++ G
Sbjct: 254 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 292
>AL391822-6|CAI14661.1| 1157|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1157
Score = 133 bits (322), Expect = 3e-30
Identities = 125/469 (26%), Positives = 201/469 (42%), Gaps = 44/469 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87
+ C A G+P+P+ W + + D S+ G + + GR G Y C A
Sbjct: 55 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 114
Query: 88 TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
N +GTA S L V+ L + L+P Q +G + L+C PP G P P ++W +
Sbjct: 115 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 172
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR-NAAGT-RESAIATLKI---- 198
+ D R+ G+L + D Y C AR + T ++ TLK+
Sbjct: 173 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTR 231
Query: 199 ---HIKPYLI----TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + T +V + G + +C G P PD+ W + GG++P + K
Sbjct: 232 GVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKF 288
Query: 252 LD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
+ + +LR+ NV D GEY C A N +G++ + + V P P ++ + G
Sbjct: 289 ENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG 348
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFP-GMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
R C A G P+PT+ W V G P +R+ T +F DT + SR
Sbjct: 349 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF--------RDTQIS-SRAV 399
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEP 427
C+ N G ++V D PP +++ P NQ + + + C +P P
Sbjct: 400 YQCNTSNEHGYLLANAFVSVL---DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIP 454
Query: 428 IIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W+ G+ + +V +G+L +K + K D G YTCVA++ GK
Sbjct: 455 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 503
Score = 116 bits (278), Expect = 7e-25
Identities = 87/288 (30%), Positives = 135/288 (46%), Gaps = 15/288 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 330 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 387
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 388 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 442
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 443 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 500
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 501 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 559
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+G +D SL + V D+G Y+C A + A YLTV P
Sbjct: 560 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRP 607
Score = 111 bits (266), Expect = 2e-23
Identities = 97/378 (25%), Positives = 153/378 (40%), Gaps = 23/378 (6%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
V R L C A G P+P I WYK G + SD + LR T+ D+G
Sbjct: 252 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKF---ENFNKALRITNVS-EEDSGE 307
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVY 141
Y+C A+N G+ R T+ V V + L EP++ A G+ L C G+P+P V
Sbjct: 308 YFCLASNKMGSIRH---TISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA-NGNPKPTVQ 363
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W NG+ L + V G ++ +D + + YQC N G + + +
Sbjct: 364 WMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 423
Query: 202 PYLITGPEDVVAQTGSSVT-FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
P +++ ++ + T C G P+P + W ++ G N+ G V ++GSL +
Sbjct: 424 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIK 483
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ D+G Y+C A N +G L V DP I P G + C P
Sbjct: 484 MIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDP 543
Query: 321 --EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
+ T+ W + I M ++ D +T+ + + D + + C A
Sbjct: 544 SLKLTVSWLKDDEPLYIGNRMKKED-------DSLTIFGVAERD----QGSYTCVASTEL 592
Query: 379 GSSFVRGKLTVTSDDDRP 396
+ LTV DRP
Sbjct: 593 DQDLAKAYLTVLGRPDRP 610
Score = 109 bits (262), Expect = 6e-23
Identities = 126/482 (26%), Positives = 199/482 (41%), Gaps = 43/482 (8%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHR-SILPAGGL 66
++P ++ LD V V P TL C G PSP I W + ++ R S G L
Sbjct: 132 KSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDL 191
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYG-TARSRNA-TLHVAVLREEFR-----LEPESKQS 119
+F + +D Y C A + T + +N TL V R + P+ S
Sbjct: 192 YFSNVMLQDMQTD---YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 248
Query: 120 AQ----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+Q G ++LEC+ G P P++ W K G L D + L I + + D+
Sbjct: 249 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 305
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W
Sbjct: 306 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 364
Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ P +V D + D I + Y C N G + A+ +++V D P
Sbjct: 365 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 423
Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
LSP + + V N R C G P PT+ W G + + G YH V++
Sbjct: 424 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 476
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
+ L I K D + C A N G + + +L V + P I P +Q
Sbjct: 477 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 529
Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+ C P + ++W + E L +R +D +L + + + D G+YTCVA
Sbjct: 530 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 588
Query: 470 SS 471
S+
Sbjct: 589 ST 590
Score = 88.2 bits (209), Expect = 2e-16
Identities = 103/395 (26%), Positives = 157/395 (39%), Gaps = 44/395 (11%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
D +++EC +G+P P+ +W +N + D R+ + ++ D R + G
Sbjct: 51 DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235
YQC ARN GT S L++ P + + VV Q G+ +T QC G P P + W
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 169
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEAE-NSVGAVSASGYLTV---- 289
S+ RV +G L NV+L D + +YSC A + + T+
Sbjct: 170 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT 229
Query: 290 -----YDPPSINL---SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
PS + +S V G C A+G P P + W +G +
Sbjct: 230 TRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG------DLPS 283
Query: 342 DKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
DK A F+ L I + + DS C A N GS +R ++V + P
Sbjct: 284 DK----AKFENFNKALRITNVSEEDS-GEYFCLASNKMGS--IRHTISVRV---KAAPYW 333
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ---NHRRNVTNDGTLVLKDL 457
+ P N L C A P+P + W GE L N R V D T++ +D
Sbjct: 334 LDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDT 392
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
S Y C S+ HG Y+ + A + + P +
Sbjct: 393 QISSRAVYQCNTSNEHG-YLLANAFVSVLDVPPRM 426
Score = 62.9 bits (146), Expect = 7e-09
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 17/279 (6%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD----NV 262
+D + ++ +C G+P P W R++ N+ RV + G+L +D
Sbjct: 43 KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 102
Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTAT- 317
EGEY C A N G A+S L V P NL P V V+ G C
Sbjct: 103 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 160
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P P +FW I ++ F V +L TD + + +
Sbjct: 161 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNV-MLQDMQTDYSCNARFHFTHTIQQ 219
Query: 378 AGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEG 435
+ F LT +R P + G ++ + ++ M + C A P P IAWY +G
Sbjct: 220 K-NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG 278
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
L + + + L + ++ + DSG Y C+AS++ G
Sbjct: 279 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 317
>AL391822-5|CAI14659.1| 1240|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1240
Score = 133 bits (322), Expect = 3e-30
Identities = 125/469 (26%), Positives = 202/469 (43%), Gaps = 44/469 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87
+ C A G+P+P+ W + + D S+ G + + GR G Y C A
Sbjct: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
Query: 88 TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
N +GTA S L V+ L + L+P Q +G + L+C PP G P P ++W +
Sbjct: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 178
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR-NAAGT-RESAIATLKI---- 198
+ D R+ G+L + D Y C AR + T ++ TLK+
Sbjct: 179 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTR 237
Query: 199 ---HIKPYLI----TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + T +V + G + +C G P PD+ W + GG++P + K
Sbjct: 238 GVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKF 294
Query: 252 LD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
+ + +LR+ NV D GEY C A N +G++ + + V P P ++ + G
Sbjct: 295 ENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG 354
Query: 311 RFTCTATGRPEPTMFWSVEGN-RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
R C A G P+PT+ W V G P +R+ T +F DT + SR
Sbjct: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF--------RDT-QISSRAV 405
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEP 427
C+ N G ++V D PP +++ P NQ + + + C +P P
Sbjct: 406 YQCNTSNEHGYLLANAFVSVL---DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIP 460
Query: 428 IIAWYFEGE-ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W+ G+ + + +V +G+L +K + K D G YTCVA++ GK
Sbjct: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509
Score = 114 bits (275), Expect = 2e-24
Identities = 86/284 (30%), Positives = 134/284 (47%), Gaps = 15/284 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 336 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 393
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 394 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 448
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 449 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 506
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 507 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 565
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+G +D SL + V D+G Y+C A + A YLTV
Sbjct: 566 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Score = 113 bits (272), Expect = 4e-24
Identities = 159/620 (25%), Positives = 249/620 (40%), Gaps = 65/620 (10%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHR-SILPAGGL 66
++P ++ LD V V P TL C G PSP I W + ++ R S G L
Sbjct: 138 KSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDL 197
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYG-TARSRNA-TLHVAVLREEFR-----LEPESKQS 119
+F + +D Y C A + T + +N TL V R + P+ S
Sbjct: 198 YFSNVMLQDMQTD---YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 254
Query: 120 AQ----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+Q G ++LEC+ G P P++ W K G L D + L I + + D+
Sbjct: 255 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 311
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W
Sbjct: 312 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370
Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ P +V D + D I + Y C N G + A+ +++V D P
Sbjct: 371 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 429
Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
LSP + + V N R C G P PT+ W G + + G YH V++
Sbjct: 430 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 482
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
+ L I K D + C A N G + + +L V + P I P +Q
Sbjct: 483 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 535
Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+ C P + ++W + E L +R +D +L + + + D G+YTCVA
Sbjct: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 594
Query: 470 SSRHGKYVWSGAL--LVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTD---TSVTLS 523
S+ + + L L D N +++LP G P +P +TD SV L+
Sbjct: 595 STELDQDLAKAYLTVLADQATPTN-------RLAALPKGRPDRPRDLELTDLAERSVRLT 647
Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583
W + +S I Y V+ + G W ++ + V L P + Y
Sbjct: 648 WIPGD-ANNSPITDYVVQFEEDQFQPG--------VWHDHSKYPGSVNSAVLRLSPYVNY 698
Query: 584 MFIVRTENSHGLSGPSPVSD 603
F V N G S PS S+
Sbjct: 699 QFRVIAINEVGSSHPSLPSE 718
Score = 88.2 bits (209), Expect = 2e-16
Identities = 103/395 (26%), Positives = 157/395 (39%), Gaps = 44/395 (11%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
D +++EC +G+P P+ +W +N + D R+ + ++ D R + G
Sbjct: 57 DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 115
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235
YQC ARN GT S L++ P + + VV Q G+ +T QC G P P + W
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 175
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEAE-NSVGAVSASGYLTV---- 289
S+ RV +G L NV+L D + +YSC A + + T+
Sbjct: 176 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT 235
Query: 290 -----YDPPSINL---SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
PS + +S V G C A+G P P + W +G +
Sbjct: 236 TRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG------DLPS 289
Query: 342 DKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
DK A F+ L I + + DS C A N GS +R ++V + P
Sbjct: 290 DK----AKFENFNKALRITNVSEEDS-GEYFCLASNKMGS--IRHTISVRV---KAAPYW 339
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ---NHRRNVTNDGTLVLKDL 457
+ P N L C A P+P + W GE L N R V D T++ +D
Sbjct: 340 LDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDT 398
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
S Y C S+ HG Y+ + A + + P +
Sbjct: 399 QISSRAVYQCNTSNEHG-YLLANAFVSVLDVPPRM 432
Score = 62.9 bits (146), Expect = 7e-09
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 17/279 (6%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD----NV 262
+D + ++ +C G+P P W R++ N+ RV + G+L +D
Sbjct: 49 KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 108
Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTAT- 317
EGEY C A N G A+S L V P NL P V V+ G C
Sbjct: 109 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 166
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P P +FW I ++ F V +L TD + + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNV-MLQDMQTDYSCNARFHFTHTIQQ 225
Query: 378 AGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEG 435
+ F LT +R P + G ++ + ++ M + C A P P IAWY +G
Sbjct: 226 K-NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG 284
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
L + + + L + ++ + DSG Y C+AS++ G
Sbjct: 285 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 323
>AL391822-4|CAI14660.1| 1347|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1347
Score = 133 bits (322), Expect = 3e-30
Identities = 125/469 (26%), Positives = 202/469 (43%), Gaps = 44/469 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87
+ C A G+P+P+ W + + D S+ G + + GR G Y C A
Sbjct: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
Query: 88 TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
N +GTA S L V+ L + L+P Q +G + L+C PP G P P ++W +
Sbjct: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 178
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR-NAAGT-RESAIATLKI---- 198
+ D R+ G+L + D Y C AR + T ++ TLK+
Sbjct: 179 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTR 237
Query: 199 ---HIKPYLI----TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + T +V + G + +C G P PD+ W + GG++P + K
Sbjct: 238 GVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKF 294
Query: 252 LD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
+ + +LR+ NV D GEY C A N +G++ + + V P P ++ + G
Sbjct: 295 ENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG 354
Query: 311 RFTCTATGRPEPTMFWSVEGN-RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
R C A G P+PT+ W V G P +R+ T +F DT + SR
Sbjct: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF--------RDT-QISSRAV 405
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEP 427
C+ N G ++V D PP +++ P NQ + + + C +P P
Sbjct: 406 YQCNTSNEHGYLLANAFVSVL---DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIP 460
Query: 428 IIAWYFEGE-ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W+ G+ + + +V +G+L +K + K D G YTCVA++ GK
Sbjct: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509
Score = 114 bits (275), Expect = 2e-24
Identities = 86/284 (30%), Positives = 134/284 (47%), Gaps = 15/284 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 336 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 393
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 394 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 448
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 449 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 506
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 507 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 565
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+G +D SL + V D+G Y+C A + A YLTV
Sbjct: 566 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Score = 113 bits (272), Expect = 4e-24
Identities = 159/620 (25%), Positives = 249/620 (40%), Gaps = 65/620 (10%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHR-SILPAGGL 66
++P ++ LD V V P TL C G PSP I W + ++ R S G L
Sbjct: 138 KSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDL 197
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYG-TARSRNA-TLHVAVLREEFR-----LEPESKQS 119
+F + +D Y C A + T + +N TL V R + P+ S
Sbjct: 198 YFSNVMLQDMQTD---YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 254
Query: 120 AQ----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+Q G ++LEC+ G P P++ W K G L D + L I + + D+
Sbjct: 255 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 311
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W
Sbjct: 312 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370
Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ P +V D + D I + Y C N G + A+ +++V D P
Sbjct: 371 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 429
Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
LSP + + V N R C G P PT+ W G + + G YH V++
Sbjct: 430 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 482
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
+ L I K D + C A N G + + +L V + P I P +Q
Sbjct: 483 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 535
Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+ C P + ++W + E L +R +D +L + + + D G+YTCVA
Sbjct: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 594
Query: 470 SSRHGKYVWSGAL--LVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTD---TSVTLS 523
S+ + + L L D N +++LP G P +P +TD SV L+
Sbjct: 595 STELDQDLAKAYLTVLADQATPTN-------RLAALPKGRPDRPRDLELTDLAERSVRLT 647
Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583
W + +S I Y V+ + G W ++ + V L P + Y
Sbjct: 648 WIPGD-ANNSPITDYVVQFEEDQFQPG--------VWHDHSKYPGSVNSAVLRLSPYVNY 698
Query: 584 MFIVRTENSHGLSGPSPVSD 603
F V N G S PS S+
Sbjct: 699 QFRVIAINEVGSSHPSLPSE 718
Score = 88.2 bits (209), Expect = 2e-16
Identities = 103/395 (26%), Positives = 157/395 (39%), Gaps = 44/395 (11%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
D +++EC +G+P P+ +W +N + D R+ + ++ D R + G
Sbjct: 57 DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 115
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235
YQC ARN GT S L++ P + + VV Q G+ +T QC G P P + W
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 175
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEAE-NSVGAVSASGYLTV---- 289
S+ RV +G L NV+L D + +YSC A + + T+
Sbjct: 176 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT 235
Query: 290 -----YDPPSINL---SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
PS + +S V G C A+G P P + W +G +
Sbjct: 236 TRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG------DLPS 289
Query: 342 DKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
DK A F+ L I + + DS C A N GS +R ++V + P
Sbjct: 290 DK----AKFENFNKALRITNVSEEDS-GEYFCLASNKMGS--IRHTISVRV---KAAPYW 339
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ---NHRRNVTNDGTLVLKDL 457
+ P N L C A P+P + W GE L N R V D T++ +D
Sbjct: 340 LDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDT 398
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
S Y C S+ HG Y+ + A + + P +
Sbjct: 399 QISSRAVYQCNTSNEHG-YLLANAFVSVLDVPPRM 432
Score = 62.9 bits (146), Expect = 7e-09
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 17/279 (6%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD----NV 262
+D + ++ +C G+P P W R++ N+ RV + G+L +D
Sbjct: 49 KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 108
Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTAT- 317
EGEY C A N G A+S L V P NL P V V+ G C
Sbjct: 109 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 166
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P P +FW I ++ F V +L TD + + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNV-MLQDMQTDYSCNARFHFTHTIQQ 225
Query: 378 AGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEG 435
+ F LT +R P + G ++ + ++ M + C A P P IAWY +G
Sbjct: 226 K-NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG 284
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
L + + + L + ++ + DSG Y C+AS++ G
Sbjct: 285 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 323
>AL391822-2|CAI14657.1| 619|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 619
Score = 133 bits (322), Expect = 3e-30
Identities = 125/469 (26%), Positives = 202/469 (43%), Gaps = 44/469 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87
+ C A G+P+P+ W + + D S+ G + + GR G Y C A
Sbjct: 61 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 120
Query: 88 TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
N +GTA S L V+ L + L+P Q +G + L+C PP G P P ++W +
Sbjct: 121 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 178
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR-NAAGT-RESAIATLKI---- 198
+ D R+ G+L + D Y C AR + T ++ TLK+
Sbjct: 179 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTR 237
Query: 199 ---HIKPYLI----TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + T +V + G + +C G P PD+ W + GG++P + K
Sbjct: 238 GVAERTPSFMYPQGTASSQMVLR-GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKF 294
Query: 252 LD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
+ + +LR+ NV D GEY C A N +G++ + + V P P ++ + G
Sbjct: 295 ENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDG 354
Query: 311 RFTCTATGRPEPTMFWSVEGN-RTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
R C A G P+PT+ W V G P +R+ T +F DT + SR
Sbjct: 355 RLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF--------RDT-QISSRAV 405
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEP 427
C+ N G ++V D PP +++ P NQ + + + C +P P
Sbjct: 406 YQCNTSNEHGYLLANAFVSVL---DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIP 460
Query: 428 IIAWYFEGE-ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W+ G+ + + +V +G+L +K + K D G YTCVA++ GK
Sbjct: 461 TLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGK 509
Score = 114 bits (275), Expect = 2e-24
Identities = 86/284 (30%), Positives = 134/284 (47%), Gaps = 15/284 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 336 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 393
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 394 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 448
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 449 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 506
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 507 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 565
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+G +D SL + V D+G Y+C A + A YLTV
Sbjct: 566 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 609
Score = 109 bits (262), Expect = 6e-23
Identities = 126/482 (26%), Positives = 199/482 (41%), Gaps = 43/482 (8%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHR-SILPAGGL 66
++P ++ LD V V P TL C G PSP I W + ++ R S G L
Sbjct: 138 KSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDL 197
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYG-TARSRNA-TLHVAVLREEFR-----LEPESKQS 119
+F + +D Y C A + T + +N TL V R + P+ S
Sbjct: 198 YFSNVMLQDMQTD---YSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 254
Query: 120 AQ----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+Q G ++LEC+ G P P++ W K G L D + L I + + D+
Sbjct: 255 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 311
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W
Sbjct: 312 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 370
Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ P +V D + D I + Y C N G + A+ +++V D P
Sbjct: 371 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 429
Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
LSP + + V N R C G P PT+ W G + + G YH V++
Sbjct: 430 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 482
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
+ L I K D + C A N G + + +L V + P I P +Q
Sbjct: 483 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 535
Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+ C P + ++W + E L +R +D +L + + + D G+YTCVA
Sbjct: 536 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 594
Query: 470 SS 471
S+
Sbjct: 595 ST 596
Score = 88.2 bits (209), Expect = 2e-16
Identities = 103/395 (26%), Positives = 157/395 (39%), Gaps = 44/395 (11%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
D +++EC +G+P P+ +W +N + D R+ + ++ D R + G
Sbjct: 57 DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 115
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235
YQC ARN GT S L++ P + + VV Q G+ +T QC G P P + W
Sbjct: 116 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 175
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEAE-NSVGAVSASGYLTV---- 289
S+ RV +G L NV+L D + +YSC A + + T+
Sbjct: 176 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLT 235
Query: 290 -----YDPPSINL---SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
PS + +S V G C A+G P P + W +G +
Sbjct: 236 TRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGG------DLPS 289
Query: 342 DKYHATAVFDGVT-VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
DK A F+ L I + + DS C A N GS +R ++V + P
Sbjct: 290 DK----AKFENFNKALRITNVSEEDS-GEYFCLASNKMGS--IRHTISVRV---KAAPYW 339
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ---NHRRNVTNDGTLVLKDL 457
+ P N L C A P+P + W GE L N R V D T++ +D
Sbjct: 340 LDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGD-TIIFRDT 398
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
S Y C S+ HG Y+ + A + + P +
Sbjct: 399 QISSRAVYQCNTSNEHG-YLLANAFVSVLDVPPRM 432
Score = 62.9 bits (146), Expect = 7e-09
Identities = 70/279 (25%), Positives = 111/279 (39%), Gaps = 17/279 (6%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKV-LDDGSLRLD----NV 262
+D + ++ +C G+P P W R++ N+ RV + G+L +D
Sbjct: 49 KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 108
Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDP---PSINLSPNSVNVESGNVARFTCT-AT 317
EGEY C A N G A+S L V P NL P V V+ G C
Sbjct: 109 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 166
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G P P +FW I ++ F V +L TD + + +
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNV-MLQDMQTDYSCNARFHFTHTIQQ 225
Query: 378 AGSSFVRGKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEG 435
+ F LT +R P + G ++ + ++ M + C A P P IAWY +G
Sbjct: 226 K-NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG 284
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
L + + + L + ++ + DSG Y C+AS++ G
Sbjct: 285 GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 323
>AJ001057-1|CAA04507.1| 1299|Homo sapiens NrCAM protein protein.
Length = 1299
Score = 133 bits (322), Expect = 3e-30
Identities = 162/663 (24%), Positives = 259/663 (39%), Gaps = 67/663 (10%)
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+K+ +G+ + LEC+ G P P +YW K L + ++ L I + D+
Sbjct: 274 NKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSEADS 330
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P + W
Sbjct: 331 GNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 389
Query: 236 RRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPP 293
+ + P + +D ++ NV Y C A N G + A+ ++ V +PP
Sbjct: 390 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 449
Query: 294 SINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA-VFD 351
I N++ V + A C G P PT+ W F G H V
Sbjct: 450 RILTPANTLYQVIANRPALLDCAFFGSPLPTIQW---------FKGAKGSALHEDIYVLH 500
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L I K DS T C A N G + L + + P I P +
Sbjct: 501 ENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDPTWIVKQPEYAVVQR 554
Query: 412 KSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
SM F C T + W + L + R V D LV+ D+ DSGTYTCVA
Sbjct: 555 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 613
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS--QN 527
++ S L V +P P A V +P PP + D SV LSW+ +
Sbjct: 614 NTTLDSVSASAVLSVVAP-TPT-----PAPVYDVPNPPLDLELTDQLDKSVQLSWTPGDD 667
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
N ++I + + L + T + QT +K L P + Y F V
Sbjct: 668 NNSPITTIHDEYEDAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVNYSFRV 716
Query: 588 RTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSK 647
NS G S PS S+ ++ ++E D +E +
Sbjct: 717 MAVNSIGKSLPSEASEQY--------------LTKASE------PDKNPTAVEGLGSEPD 756
Query: 648 TIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFL 707
+ + W+ LN + G + ++ + + T + +VS + ++ + Y
Sbjct: 757 NLVITWKPLNGFEFNGPGLQYKVSWRQKVGDDEWTSVVVANVSKYIVSGTPTFVPY-LIK 815
Query: 708 IPFYKKFEGKPSNSRV-AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITG 766
+ P + V + +D+P P N+ + ++N+T + W P L+ G + G
Sbjct: 816 VQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQG 875
Query: 767 YNV 769
Y +
Sbjct: 876 YRI 878
Score = 107 bits (257), Expect = 2e-22
Identities = 91/290 (31%), Positives = 130/290 (44%), Gaps = 21/290 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLF 67
APY I P ++ ++ + TL CRA G+P P I W GV + D R I G
Sbjct: 355 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI--DGDTI 412
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESK--QSAQGDT 124
R + VY C A+N YG A V VL E R L P + Q
Sbjct: 413 IFSNVQER---SSAVYQCNASNEYGYLL---ANAFVNVLAEPPRILTPANTLYQVIANRP 466
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+L+C GSP P + W K + D + L + G L I A++ G Y C+ARN
Sbjct: 467 ALLDC-AFFGSPLPTIQWFKGAKGSALHEDIYV-LHENGTLEIPVAQKDSTGTYTCVARN 524
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGG 242
G ++ + L+I +++ PE V Q GS V+F+C+V D VLW +
Sbjct: 525 KLGMAKNEV-HLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD--NR 581
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+P +D L + +V D G Y+C A ++ +VSAS L+V P
Sbjct: 582 ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 631
Score = 96.7 bits (230), Expect = 4e-19
Identities = 181/808 (22%), Positives = 305/808 (37%), Gaps = 77/808 (9%)
Query: 30 TLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
+L C A G P+P I W K G+L + T L+ H +D+G Y C A
Sbjct: 284 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT----LQIIHVS-EADSGNYQCIAK 338
Query: 89 NSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N+ G T+ V V + + P++ + G+ L C G+P+P + W NG
Sbjct: 339 NALGAIHH---TISVRVKAAPYWITAPQNLVLSPGEDGTLICRA-NGNPKPRISWLTNGV 394
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
+ D +DG ++ + ++ + YQC A N G A A + + +P I
Sbjct: 395 PIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL-LANAFVNVLAEPPRILT 453
Query: 208 PEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
P + + Q ++ C G PLP + W + A G + + ++G+L +
Sbjct: 454 PANTLYQVIANRPALLDCAFFGSPLPTIQWFKGAKGSALHEDIYVLHENGTLEIPVAQKD 513
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA--TGRPEPT 323
G Y+C A N +G +L + DP I P V+ G++ F C T
Sbjct: 514 STGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLT 573
Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
+ W ++ NR + P R T D + V ++D D T C A S
Sbjct: 574 VLW-LKDNREL--PSDER----FTVDKDHLVVADVSD----DDSGTYTCVANTTLDSVSA 622
Query: 384 RGKLTVTSDDDRPPPI--ITNGPSNQTLP---IKSMAVFPCTAICTPEPIIAWYFEGEAL 438
L+V + P P+ + N P + L KS+ + PI + E E
Sbjct: 623 SAVLSVVAPTPTPAPVYDVPNPPLDLELTDQLDKSVQLSWTPGDDNNSPITTIHDEYEDA 682
Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV-WSGALLVDSPINPNIHFFRA 497
+ H+ + + T V SGT T A + YV +S ++ + I ++ +
Sbjct: 683 M--HKPGLWHHQTEV--------SGTQT-TAQLKLSPYVNYSFRVMAVNSIGKSLPSEAS 731
Query: 498 ADVSSLPGPPTKPITH----NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553
+ P K T ++ ++W N + G Q +V R+ + +
Sbjct: 732 EQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFEFNG-PGLQYKVSWRQKVGDDEW 790
Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
VV+A + + Y+V + Y+ V+ N G + P P G+D
Sbjct: 791 TS-----VVVA---NVSKYIVSGTPTFVPYLIKVQALNDMGFA-PEPAVVMGHSGEDLPM 841
Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673
+ G R N++ + E + P+ K+I+ + YY + R +
Sbjct: 842 VAPG-------NVRVNVVNSTLAE-VHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRH 893
Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
I E K + + + L ++ Y + K EG S RV T + VP
Sbjct: 894 I----EKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSV 949
Query: 734 PPINIEMFILNTT--TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791
P + I+N T ++ L+W PP NGI+T Y + ++ +
Sbjct: 950 PS---SLKIVNPTLDSLTLEWDPP--SHPNGILTEYTLKYQPINNTHELGPLVDLKIPAN 1004
Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLG 819
T + NL Y A+T G G
Sbjct: 1005 KTRWTLKNLNFTTRYKFYFYAQTSAGSG 1032
Score = 68.1 bits (159), Expect = 2e-10
Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
+ P I +Q P D + + + C A G P P+ W + G + D ++ P G
Sbjct: 39 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 98
Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
+ + G+ + GVY C A N G A S N + + L + +LEP + QS G
Sbjct: 99 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 156
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
++VL C PP G P P ++W N L + R+ G+L + D Y C A
Sbjct: 157 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 215
Query: 183 R 183
R
Sbjct: 216 R 216
Score = 58.4 bits (135), Expect = 1e-07
Identities = 67/305 (21%), Positives = 116/305 (38%), Gaps = 30/305 (9%)
Query: 200 IKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
++P IT P+D + ++ QC G P P W R+ ++ + + G+
Sbjct: 38 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 97
Query: 258 RLDNVILAD------EGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309
L I+++ EG Y C A N GA ++ + P + ++SG
Sbjct: 98 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 157
Query: 310 ARFTCTAT-GRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAV-----FDGVTVLTI 358
C G P P +FW + + + G++ D Y + + D +
Sbjct: 158 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 217
Query: 359 NDTDKNDSRNTIVCSAVNYAG-SSFVRGKLTVT------SDDDRPPPIIT--NGPSNQTL 409
N T + I ++ + + L+ T S +RPP +T SN+
Sbjct: 218 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEE 277
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
++ C A P PII W E L +N + TL + + ++DSG Y C+A
Sbjct: 278 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 337
Query: 470 SSRHG 474
+ G
Sbjct: 338 KNALG 342
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 12/218 (5%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177
+ +V++C +G P P+ W +NG D D + + G G L+I + +T G
Sbjct: 57 ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 115
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235
YQC ARN G S ++ P + E + Q+G S+ CR G P P + W
Sbjct: 116 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 175
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEAE-NSVGAVSASGYLTVYDPP 293
++ RV +G L NV+ D E Y C A N + ++V
Sbjct: 176 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISV-KVI 234
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
S++ +++ + F + R P F + EGN
Sbjct: 235 SVDELNDTIAANLSD-TEFYGAKSSRERPPTFLTPEGN 271
>AF172277-2|AAF22283.1| 1236|Homo sapiens NgCAM-related related cell
adhesion molecule /alternative carboxyl terminus
protein.
Length = 1236
Score = 131 bits (316), Expect = 2e-29
Identities = 139/497 (27%), Positives = 201/497 (40%), Gaps = 47/497 (9%)
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+K+ +G+ + LEC+ G P P +YW K L + ++ L I + D+
Sbjct: 279 NKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSEADS 335
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P + W
Sbjct: 336 GNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 394
Query: 236 RRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPP 293
+ + P + +D ++ NV Y C A N G + A+ ++ V +PP
Sbjct: 395 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 454
Query: 294 SINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA-VFD 351
I N++ V + A C G P PT+ W F G H V
Sbjct: 455 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDIYVLH 505
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L I K DS T C A N G + L + + P I P +
Sbjct: 506 ENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDPTWIVKQPEYAVVQR 559
Query: 412 KSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
SM F C T + W + L + R V D LV+ D+ DSGTYTCVA
Sbjct: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 618
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS---Q 526
++ S L V +P P A V +P PP + D SV LSW+
Sbjct: 619 NTTLDSVSASAVLSVVAP-TPT-----PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDD 672
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
NN + I+ Y+ + + L + T + QT +K L P + Y F
Sbjct: 673 NNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVNYSFR 720
Query: 587 VRTENSHGLSGPSPVSD 603
V NS G S PS S+
Sbjct: 721 VMAVNSIGKSLPSEASE 737
Score = 107 bits (256), Expect = 3e-22
Identities = 91/290 (31%), Positives = 130/290 (44%), Gaps = 21/290 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLF 67
APY I P ++ ++ + TL CRA G+P P I W GV + D R I G
Sbjct: 360 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI--DGDTI 417
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESK--QSAQGDT 124
R + VY C A+N YG A V VL E R L P + Q
Sbjct: 418 IFSNVQER---SSAVYQCNASNEYGYLL---ANAFVNVLAEPPRILTPANTLYQVIANRP 471
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+L+C GSP P + W K + D + L + G L I A++ G Y C+ARN
Sbjct: 472 ALLDC-AFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPVAQKDSTGTYTCVARN 529
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGG 242
G ++ + L+I +++ PE V Q GS V+F+C+V D VLW +
Sbjct: 530 KLGMAKNEV-HLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD--NR 586
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+P +D L + +V D G Y+C A ++ +VSAS L+V P
Sbjct: 587 ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 636
Score = 101 bits (241), Expect = 2e-20
Identities = 183/808 (22%), Positives = 308/808 (38%), Gaps = 77/808 (9%)
Query: 30 TLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
+L C A G P+P I W K G+L + T L+ H +D+G Y C A
Sbjct: 289 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT----LQIIHVS-EADSGNYQCIAK 343
Query: 89 NSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N+ G T+ V V + + P++ + G+ L C G+P+P + W NG
Sbjct: 344 NALGAIHH---TISVRVKAAPYWITAPQNLVLSPGEDGTLICRA-NGNPKPRISWLTNGV 399
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
+ D +DG ++ + ++ + YQC A N G A A + + +P I
Sbjct: 400 PIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL-LANAFVNVLAEPPRILT 458
Query: 208 PEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
P + + Q ++ C G PLP + W + A G + + ++G+L +
Sbjct: 459 PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKD 518
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA--TGRPEPT 323
G Y+C A N +G +L + DP I P V+ G++ F C T
Sbjct: 519 STGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLT 578
Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
+ W ++ NR + P R T D + V ++D D T C A S
Sbjct: 579 VLW-LKDNREL--PSDER----FTVDKDHLVVADVSD----DDSGTYTCVANTTLDSVSA 627
Query: 384 RGKLTVTSDDDRPPPI--ITNGPSNQTLP---IKSMAVFPCTAICTPEPIIAWYFEGEAL 438
L+V + P P+ + N P + L KS+ + PI + E E
Sbjct: 628 SAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDA 687
Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV-WSGALLVDSPINPNIHFFRA 497
+ H+ + + T V SGT T A + YV +S ++ + I ++ +
Sbjct: 688 M--HKPGLWHHQTEV--------SGTQT-TAQLKLSPYVNYSFRVMAVNSIGKSLPSEAS 736
Query: 498 ADVSSLPGPPTKPITH----NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553
+ P K T ++ ++W N S+ G Q +V R+ G++
Sbjct: 737 EQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNG-PGLQYKVSWRQK-DGDDE 794
Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ VV+A + + Y+V + Y+ V+ N G + P P G+D
Sbjct: 795 WTS----VVVA---NVSKYIVSGTPTFVPYLIKVQALNDMGFA-PEPAVVMGHSGEDLPM 846
Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673
+ G R N++ + E + P+ K+I+ + YY + R +
Sbjct: 847 VAPG-------NVRVNVVNSTLAE-VHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRH 898
Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
I E K + + + L ++ Y + K EG S RV T + VP
Sbjct: 899 I----EKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSA 954
Query: 734 PPINIEMFILNTT--TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791
P + I+N T ++ L+W PP NGI+T Y + ++ +
Sbjct: 955 PS---SLKIVNPTLDSLTLEWDPP--SHPNGILTEYTLKYQPINSTHELGPLVDLKIPAN 1009
Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLG 819
T + NL Y A+T G G
Sbjct: 1010 KTRWTLKNLNFSTRYKFYFYAQTSAGSG 1037
Score = 68.1 bits (159), Expect = 2e-10
Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
+ P I +Q P D + + + C A G P P+ W + G + D ++ P G
Sbjct: 44 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103
Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
+ + G+ + GVY C A N G A S N + + L + +LEP + QS G
Sbjct: 104 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 161
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
++VL C PP G P P ++W N L + R+ G+L + D Y C A
Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 220
Query: 183 R 183
R
Sbjct: 221 R 221
Score = 58.4 bits (135), Expect = 1e-07
Identities = 67/305 (21%), Positives = 116/305 (38%), Gaps = 30/305 (9%)
Query: 200 IKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
++P IT P+D + ++ QC G P P W R+ ++ + + G+
Sbjct: 43 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 102
Query: 258 RLDNVILAD------EGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309
L I+++ EG Y C A N GA ++ + P + ++SG
Sbjct: 103 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 162
Query: 310 ARFTCTAT-GRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAV-----FDGVTVLTI 358
C G P P +FW + + + G++ D Y + + D +
Sbjct: 163 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 222
Query: 359 NDTDKNDSRNTIVCSAVNYAG-SSFVRGKLTVT------SDDDRPPPIIT--NGPSNQTL 409
N T + I ++ + + L+ T S +RPP +T SN+
Sbjct: 223 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEE 282
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
++ C A P PII W E L +N + TL + + ++DSG Y C+A
Sbjct: 283 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 342
Query: 470 SSRHG 474
+ G
Sbjct: 343 KNALG 347
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 12/218 (5%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177
+ +V++C +G P P+ W +NG D D + + G G L+I + +T G
Sbjct: 62 ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 120
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235
YQC ARN G S ++ P + E + Q+G S+ CR G P P + W
Sbjct: 121 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 180
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEAE-NSVGAVSASGYLTVYDPP 293
++ RV +G L NV+ D E Y C A N + ++V
Sbjct: 181 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISV-KVI 239
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
S++ +++ + F + R P F + EGN
Sbjct: 240 SVDELNDTIAANLSD-TEFYGAKSSRERPPTFLTPEGN 276
>AF172277-1|AAF22282.1| 1308|Homo sapiens NgCAM-related related cell
adhesion molecule protein.
Length = 1308
Score = 131 bits (316), Expect = 2e-29
Identities = 139/497 (27%), Positives = 201/497 (40%), Gaps = 47/497 (9%)
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+K+ +G+ + LEC+ G P P +YW K L + ++ L I + D+
Sbjct: 279 NKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSEADS 335
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P + W
Sbjct: 336 GNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 394
Query: 236 RRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPP 293
+ + P + +D ++ NV Y C A N G + A+ ++ V +PP
Sbjct: 395 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 454
Query: 294 SINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA-VFD 351
I N++ V + A C G P PT+ W F G H V
Sbjct: 455 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDIYVLH 505
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L I K DS T C A N G + L + + P I P +
Sbjct: 506 ENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDPTWIVKQPEYAVVQR 559
Query: 412 KSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
SM F C T + W + L + R V D LV+ D+ DSGTYTCVA
Sbjct: 560 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 618
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS---Q 526
++ S L V +P P A V +P PP + D SV LSW+
Sbjct: 619 NTTLDSVSASAVLSVVAP-TPT-----PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDD 672
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
NN + I+ Y+ + + L + T + QT +K L P + Y F
Sbjct: 673 NNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVNYSFR 720
Query: 587 VRTENSHGLSGPSPVSD 603
V NS G S PS S+
Sbjct: 721 VMAVNSIGKSLPSEASE 737
Score = 107 bits (256), Expect = 3e-22
Identities = 91/290 (31%), Positives = 130/290 (44%), Gaps = 21/290 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLF 67
APY I P ++ ++ + TL CRA G+P P I W GV + D R I G
Sbjct: 360 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI--DGDTI 417
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESK--QSAQGDT 124
R + VY C A+N YG A V VL E R L P + Q
Sbjct: 418 IFSNVQER---SSAVYQCNASNEYGYLL---ANAFVNVLAEPPRILTPANTLYQVIANRP 471
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+L+C GSP P + W K + D + L + G L I A++ G Y C+ARN
Sbjct: 472 ALLDC-AFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPVAQKDSTGTYTCVARN 529
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGG 242
G ++ + L+I +++ PE V Q GS V+F+C+V D VLW +
Sbjct: 530 KLGMAKNEV-HLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD--NR 586
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+P +D L + +V D G Y+C A ++ +VSAS L+V P
Sbjct: 587 ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 636
Score = 101 bits (241), Expect = 2e-20
Identities = 183/808 (22%), Positives = 308/808 (38%), Gaps = 77/808 (9%)
Query: 30 TLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
+L C A G P+P I W K G+L + T L+ H +D+G Y C A
Sbjct: 289 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT----LQIIHVS-EADSGNYQCIAK 343
Query: 89 NSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N+ G T+ V V + + P++ + G+ L C G+P+P + W NG
Sbjct: 344 NALGAIHH---TISVRVKAAPYWITAPQNLVLSPGEDGTLICRA-NGNPKPRISWLTNGV 399
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
+ D +DG ++ + ++ + YQC A N G A A + + +P I
Sbjct: 400 PIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL-LANAFVNVLAEPPRILT 458
Query: 208 PEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
P + + Q ++ C G PLP + W + A G + + ++G+L +
Sbjct: 459 PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKD 518
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA--TGRPEPT 323
G Y+C A N +G +L + DP I P V+ G++ F C T
Sbjct: 519 STGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLT 578
Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
+ W ++ NR + P R T D + V ++D D T C A S
Sbjct: 579 VLW-LKDNREL--PSDER----FTVDKDHLVVADVSD----DDSGTYTCVANTTLDSVSA 627
Query: 384 RGKLTVTSDDDRPPPI--ITNGPSNQTLP---IKSMAVFPCTAICTPEPIIAWYFEGEAL 438
L+V + P P+ + N P + L KS+ + PI + E E
Sbjct: 628 SAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPITKFIIEYEDA 687
Query: 439 IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV-WSGALLVDSPINPNIHFFRA 497
+ H+ + + T V SGT T A + YV +S ++ + I ++ +
Sbjct: 688 M--HKPGLWHHQTEV--------SGTQT-TAQLKLSPYVNYSFRVMAVNSIGKSLPSEAS 736
Query: 498 ADVSSLPGPPTKPITH----NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNT 553
+ P K T ++ ++W N S+ G Q +V R+ G++
Sbjct: 737 EQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNG-PGLQYKVSWRQK-DGDDE 794
Query: 554 PRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ VV+A + + Y+V + Y+ V+ N G + P P G+D
Sbjct: 795 WTS----VVVA---NVSKYIVSGTPTFVPYLIKVQALNDMGFA-PEPAVVMGHSGEDLPM 846
Query: 614 LWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673
+ G R N++ + E + P+ K+I+ + YY + R +
Sbjct: 847 VAPG-------NVRVNVVNSTLAE-VHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRH 898
Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
I E K + + + L ++ Y + K EG S RV T + VP
Sbjct: 899 I----EKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSA 954
Query: 734 PPINIEMFILNTT--TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQ 791
P + I+N T ++ L+W PP NGI+T Y + ++ +
Sbjct: 955 PS---SLKIVNPTLDSLTLEWDPP--SHPNGILTEYTLKYQPINSTHELGPLVDLKIPAN 1009
Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLG 819
T + NL Y A+T G G
Sbjct: 1010 KTRWTLKNLNFSTRYKFYFYAQTSAGSG 1037
Score = 68.1 bits (159), Expect = 2e-10
Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
+ P I +Q P D + + + C A G P P+ W + G + D ++ P G
Sbjct: 44 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 103
Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
+ + G+ + GVY C A N G A S N + + L + +LEP + QS G
Sbjct: 104 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 161
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
++VL C PP G P P ++W N L + R+ G+L + D Y C A
Sbjct: 162 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 220
Query: 183 R 183
R
Sbjct: 221 R 221
Score = 58.4 bits (135), Expect = 1e-07
Identities = 67/305 (21%), Positives = 116/305 (38%), Gaps = 30/305 (9%)
Query: 200 IKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
++P IT P+D + ++ QC G P P W R+ ++ + + G+
Sbjct: 43 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 102
Query: 258 RLDNVILAD------EGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309
L I+++ EG Y C A N GA ++ + P + ++SG
Sbjct: 103 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 162
Query: 310 ARFTCTAT-GRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAV-----FDGVTVLTI 358
C G P P +FW + + + G++ D Y + + D +
Sbjct: 163 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 222
Query: 359 NDTDKNDSRNTIVCSAVNYAG-SSFVRGKLTVT------SDDDRPPPIIT--NGPSNQTL 409
N T + I ++ + + L+ T S +RPP +T SN+
Sbjct: 223 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEE 282
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
++ C A P PII W E L +N + TL + + ++DSG Y C+A
Sbjct: 283 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 342
Query: 470 SSRHG 474
+ G
Sbjct: 343 KNALG 347
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 12/218 (5%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177
+ +V++C +G P P+ W +NG D D + + G G L+I + +T G
Sbjct: 62 ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 120
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235
YQC ARN G S ++ P + E + Q+G S+ CR G P P + W
Sbjct: 121 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 180
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEAE-NSVGAVSASGYLTVYDPP 293
++ RV +G L NV+ D E Y C A N + ++V
Sbjct: 181 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISV-KVI 239
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
S++ +++ + F + R P F + EGN
Sbjct: 240 SVDELNDTIAANLSD-TEFYGAKSSRERPPTFLTPEGN 276
>AK128020-1|BAC87234.1| 595|Homo sapiens ursor. protein.
Length = 595
Score = 129 bits (312), Expect = 5e-29
Identities = 92/332 (27%), Positives = 137/332 (41%), Gaps = 19/332 (5%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-----GV-LVVSDTHRSILP 62
G AP + E P DVTV + A L CRA G P P + W +G G+ L RS P
Sbjct: 46 GHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQP 105
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
G+ F + D Y CEA N +G ++ + + + + +G
Sbjct: 106 DSGVLFFESV---APEDQAPYVCEARNVFGKVQAEARLIVTGHAPPQIASSAPTVRVLEG 162
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
V L C+ G P P +W K+G+ L SR + G+L + A Q AGRY C+A
Sbjct: 163 QPVSLPCIVLAGRPLPERHWLKDGRPL--PPGSRHSIRADGSLHLDRALQEHAGRYSCVA 220
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
N AG++ + L + + P + + G + C G P P + W +
Sbjct: 221 TNTAGSQHRDV-ELVVQVPPRIHPTATHHITNEGVPASLPCVASGVPAPTITWTKETNAL 279
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS---- 298
V +G+L + D G Y C A N+VG S L+V P I+++
Sbjct: 280 TSRGPHYNVSKEGTLLIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRN 339
Query: 299 ---PNSVNVESGNVARFTCTATGRPEPTMFWS 327
P V ++G C A G P P + W+
Sbjct: 340 ADVPLQVTAKAGEEVTLDCEAKGSPPPLVTWT 371
Score = 128 bits (309), Expect = 1e-28
Identities = 124/413 (30%), Positives = 171/413 (41%), Gaps = 37/413 (8%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPE 137
DAG Y C A N G A +A + +AV E P G + +L C G P
Sbjct: 22 DAGTYTCRAVNELGDA---SAEIQLAVGHAPQLTELPRDVTVELGRSALLACRAT-GRPP 77
Query: 138 PNVYWKK-NGQTL---LFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
P V W++ +GQ L L G SR D G L + D Y C ARN G + A
Sbjct: 78 PTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFG-KVQA 136
Query: 193 IATLKI--HIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSAGGGNMPLG-R 248
A L + H P + + V G V+ C V G PLP+ W + G +P G R
Sbjct: 137 EARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKD--GRPLPPGSR 194
Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGN 308
+ DGSL LD + G YSC A N+ G+ L V PP I+ + G
Sbjct: 195 HSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVPPRIHPTATHHITNEGV 254
Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
A C A+G P PT+ W+ E N ++ H +G L I D+
Sbjct: 255 PASLPCVASGVPAPTITWTKETN------ALTSRGPHYNVSKEG--TLLIAQPSAQDA-G 305
Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA------VFPCTAI 422
VC+A N G S +L+V + P I NG N +P++ A C A
Sbjct: 306 AYVCTATNTVGFSSQEMRLSVNT----KPRIHMNGSRNADVPLQVTAKAGEEVTLDCEAK 361
Query: 423 CTPEPIIAWYFEGEALIQ-NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+P P++ W + + +R + G+L L + DSG Y C AS+ G
Sbjct: 362 GSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAG 414
Score = 123 bits (297), Expect = 3e-27
Identities = 112/348 (32%), Positives = 143/348 (41%), Gaps = 26/348 (7%)
Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
G L I A++ DAG Y C A N G + I L + P L P DV + G S
Sbjct: 11 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQ-LAVGHAPQLTELPRDVTVELGRSALLA 69
Query: 223 CRVGGDPLPDVLWRRSAG---GGNMPLGR---VKVLDDGSLRLDNVILADEGEYSCEAEN 276
CR G P P V WRR G G + GR + D G L ++V D+ Y CEA N
Sbjct: 70 CRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARN 129
Query: 277 SVGAVSASGYLTV--YDPPSINLSPNSVNVESGNVARFTCTA-TGRPEPTMFWSVEGNRT 333
G V A L V + PP I S +V V G C GRP P W +G
Sbjct: 130 VFGKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRP- 188
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
P SR A DG L D + C A N AGS R V
Sbjct: 189 --LPPGSRHSIRA----DGSLHL---DRALQEHAGRYSCVATNTAGSQH-RDVELVVQVP 238
Query: 394 DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGTL 452
R P T+ +N+ +P A PC A P P I W E AL + NV+ +GTL
Sbjct: 239 PRIHPTATHHITNEGVP----ASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEGTL 294
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADV 500
++ D+G Y C A++ G L V++ +++ R ADV
Sbjct: 295 LIAQPSAQDAGAYVCTATNTVGFSSQEMRLSVNTKPRIHMNGSRNADV 342
Score = 103 bits (247), Expect = 4e-21
Identities = 90/287 (31%), Positives = 118/287 (41%), Gaps = 21/287 (7%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT P I V V QP +L C G P P W K G + + SI G
Sbjct: 142 VTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLPPGSRHSIRADG 201
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQG 122
L RA + AG Y C ATN+ G+ + R+ L V V R+ P + + +G
Sbjct: 202 SLHLDRA----LQEHAGRYSCVATNTAGS-QHRDVELVVQVPP---RIHPTATHHITNEG 253
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
L C+ G P P + W K L G +G L+ Q + Q DAG Y C A
Sbjct: 254 VPASLPCVAS-GVPAPTITWTKETNALTSRGPHYNVSKEGTLLIAQPSAQ-DAGAYVCTA 311
Query: 183 RNAAGTRESAIATLKIHIKPYL-ITG------PEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
N G + L ++ KP + + G P V A+ G VT C G P P V W
Sbjct: 312 TNTVGFSSQEMR-LSVNTKPRIHMNGSRNADVPLQVTAKAGEEVTLDCEAKGSPPPLVTW 370
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVS 282
+ + R +L GSLRL V + D G Y C A N G+ S
Sbjct: 371 TKDSRPVPPITNRYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSAS 417
Score = 91.5 bits (217), Expect = 2e-17
Identities = 79/288 (27%), Positives = 122/288 (42%), Gaps = 12/288 (4%)
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
G LR+ D G Y+C A N +G SA L V P + P V VE G A C
Sbjct: 11 GKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLAC 70
Query: 315 TATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
ATGRP PT+ W +G + G R + GV ++ + + VC
Sbjct: 71 RATGRPPPTVTWRRGDGQPLGLRLGAGRGS-RSRQPDSGVLFF---ESVAPEDQAPYVCE 126
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC-TPEPIIAWY 432
A N G +L VT PP I ++ P+ + L + +++ PC + P P W
Sbjct: 127 ARNVFGKVQAEARLIVTG--HAPPQIASSAPTVRVLEGQPVSL-PCIVLAGRPLPERHWL 183
Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+G L R ++ DG+L L + +G Y+CVA++ G L+V P P I
Sbjct: 184 KDGRPLPPGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVP--PRI 241
Query: 493 HFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQV 540
H +++ P + P + + T++W++ +S Y V
Sbjct: 242 HPTATHHITNEGVPASLPCVASGV-PAPTITWTKETNALTSRGPHYNV 288
Score = 51.2 bits (117), Expect = 2e-05
Identities = 31/81 (38%), Positives = 41/81 (50%), Gaps = 5/81 (6%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHR-SILPAGGLFFLRATHGRV 76
PL VT + TL+C A GSP P + W K V T+R +LP+G L + G
Sbjct: 343 PLQVTAKAGEEVTLDCEAKGSPPPLVTWTKDSRPVPPITNRYGLLPSGSLRLAQVQVG-- 400
Query: 77 HSDAGVYWCEATNSYGTARSR 97
D+G Y C A+N G+A R
Sbjct: 401 --DSGHYECTASNPAGSASHR 419
>AK093583-1|BAC04201.1| 329|Homo sapiens protein ( Homo sapiens
cDNA FLJ36264 fis, clone THYMU2002815, weakly similar to
AXONIN-1 PRECURSOR. ).
Length = 329
Score = 129 bits (311), Expect = 7e-29
Identities = 88/302 (29%), Positives = 134/302 (44%), Gaps = 11/302 (3%)
Query: 28 PATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
P L C + G P+P + W K G L + + P+G L +A +H AG Y C
Sbjct: 4 PVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALP--IH--AGRYTCS 59
Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
A NS G A ++ L V L P ++ + V+L C G P P + W+K G
Sbjct: 60 ARNSAGVAH-KHVFLTVQASPVVKPL-PSVVRAVAEEEVLLPC-EASGIPRPTITWQKEG 116
Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
+ +++ + GG L I A DAG Y CIA+N+AG+ L + + P +
Sbjct: 117 LNVATGVSTQV--LPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGK-TRLVVQVPPVIEN 173
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILAD 266
G D+ GS C+ G P P++ W + + G+ + G L + N+ D
Sbjct: 174 GLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNLEGQD 233
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
G Y+C AEN+VG +LT+ P P ++ G+ C A G P P + W
Sbjct: 234 AGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGW 293
Query: 327 SV 328
+V
Sbjct: 294 TV 295
Score = 110 bits (264), Expect = 3e-23
Identities = 79/258 (30%), Positives = 110/258 (42%), Gaps = 13/258 (5%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
++T +P + P V + L C A G P P I W K G+ V + +LP G
Sbjct: 72 FLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLNVATGVSTQVLPGG 131
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
LR H DAG Y C A NS G+A + T V + + +G
Sbjct: 132 Q---LRIAHAS-PEDAGNYLCIAKNSAGSAMGK--TRLVVQVPPVIENGLPDLSTTEGSH 185
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
L C RGSPEPN+ W K+GQ + + + + G L++++ DAG Y C A N
Sbjct: 186 AFLPC-KARGSPEPNITWDKDGQP-VSGAEGKFTIQPSGELLVKNLEGQDAGTYTCTAEN 243
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAG 240
A G R L I + P T P D + G + +C G P P + W R G
Sbjct: 244 AVG-RARRRVHLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTG 302
Query: 241 GGNMPLGRVKVLDDGSLR 258
G + +G + D G LR
Sbjct: 303 LGLLGMGGTESQDTGRLR 320
Score = 109 bits (263), Expect = 4e-23
Identities = 93/308 (30%), Positives = 127/308 (41%), Gaps = 20/308 (6%)
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
VVL C G P P V W K G L G S + G L I A AGRY C ARN
Sbjct: 5 VVLTC-HSTGIPAPTVSWSKAGAQLGARG-SGYRVSPSGALEIGQALPIHAGRYTCSARN 62
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
+AG + L + P + P V A V C G P P + W++ G N+
Sbjct: 63 SAGVAHKHVF-LTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKE--GLNV 119
Query: 245 PLG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
G +VL G LR+ + D G Y C A+NS G+ L V PP I ++
Sbjct: 120 ATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVPPVIENGLPDLS 179
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G+ A C A G PEP + W +G +S + T G L + + +
Sbjct: 180 TTEGSHAFLPCKARGSPEPNITWDKDGQ------PVSGAEGKFTIQPSG--ELLVKNLEG 231
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
D+ T C+A N G + R LT+ P+ T P +++L + C A
Sbjct: 232 QDA-GTYTCTAENAVGRARRRVHLTIL-----VLPVFTTLPGDRSLRLGDRLWLRCAARG 285
Query: 424 TPEPIIAW 431
+P P I W
Sbjct: 286 SPTPRIGW 293
Score = 107 bits (258), Expect = 2e-22
Identities = 77/258 (29%), Positives = 114/258 (44%), Gaps = 16/258 (6%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
V C G P P V W ++ +V G+L + + G Y+C A NS
Sbjct: 5 VVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYTCSARNSA 64
Query: 279 GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338
G +LTV P + P+ V + C A+G P PT+ W EG + G
Sbjct: 65 GVAHKHVFLTVQASPVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQKEGLN--VATG 122
Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP 398
+S T V G L I D+ N + C A N AGS+ + +L V + PP
Sbjct: 123 VS------TQVLPGGQ-LRIAHASPEDAGNYL-CIAKNSAGSAMGKTRLVV-----QVPP 169
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALI-QNHRRNVTNDGTLVLKDL 457
+I NG + + S A PC A +PEP I W +G+ + + + G L++K+L
Sbjct: 170 VIENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSGELLVKNL 229
Query: 458 DKSDSGTYTCVASSRHGK 475
+ D+GTYTC A + G+
Sbjct: 230 EGQDAGTYTCTAENAVGR 247
Score = 51.2 bits (117), Expect = 2e-05
Identities = 48/175 (27%), Positives = 67/175 (38%), Gaps = 14/175 (8%)
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
TC +TG P PT+ WS G + G Y + G + + R T C
Sbjct: 8 TCHSTGIPAPTVSWSKAGAQL----GARGSGYRVSP--SGALEIG-QALPIHAGRYT--C 58
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
SA N AG + LTV + P++ PS + + PC A P P I W
Sbjct: 59 SARNSAGVAHKHVFLTVQAS-----PVVKPLPSVVRAVAEEEVLLPCEASGIPRPTITWQ 113
Query: 433 FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
EG + V G L + D+G Y C+A + G + L+V P
Sbjct: 114 KEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVP 168
>U55258-1|AAC50765.1| 1299|Homo sapiens hBRAVO/Nr-CAM precursor
protein.
Length = 1299
Score = 127 bits (306), Expect = 3e-28
Identities = 158/665 (23%), Positives = 266/665 (40%), Gaps = 71/665 (10%)
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+K+ +G+ + LEC+ G P P +YW K L + ++ L I + D+
Sbjct: 274 NKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSEADS 330
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P + W
Sbjct: 331 GNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 389
Query: 236 RRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPP 293
+ + P + +D ++ NV Y C A N G + A+ ++ V +PP
Sbjct: 390 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 449
Query: 294 SINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT-AVFD 351
I N++ V + A C G P PT+ W + + + + T + D
Sbjct: 450 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIKD 509
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
++ + DS T C A R KL + ++ + P +
Sbjct: 510 ATWIVKEIPVAQKDSTGTYTCVA---------RNKLGMAKNE------VHLQPEYAVVQR 554
Query: 412 KSMAVFPCTA--ICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
SM F C T + W + L + R V D LV+ D+ DSGTYTCVA
Sbjct: 555 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKD-HLVVADVSDDDSGTYTCVA 613
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS---Q 526
++ S L V +P P A V +P PP + D SV LSW+
Sbjct: 614 NTTLDSVSASAVLSVVAP-TPT-----PAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDD 667
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
NN + I+ Y+ + + L + T + QT +K L P + Y F
Sbjct: 668 NNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVNYSFR 715
Query: 587 VRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDS 646
V NS G S PS S+ ++ ++E D +E +
Sbjct: 716 VMAVNSIGKSLPSEASEQY--------------LTKASE------PDKNPTAVEGLGSEP 755
Query: 647 KTIKLMWEILNFYYLEGLFIYFR-PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEF 705
+++ W+ LN + G + ++ + E +++ +N VS + ++ + Y
Sbjct: 756 DNLEITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVAN-VSKYIVSGTPTFVPY-L 813
Query: 706 FLIPFYKKFEGKPSNSRV-AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGII 764
+ P + V + +D+P P N+ + ++N+T + W P L+ G +
Sbjct: 814 IKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHL 873
Query: 765 TGYNV 769
GY +
Sbjct: 874 QGYRI 878
Score = 91.9 bits (218), Expect = 1e-17
Identities = 92/300 (30%), Positives = 130/300 (43%), Gaps = 41/300 (13%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLF 67
APY I P ++ ++ + TL CRA G+P P I W GV + D R I G
Sbjct: 355 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI--DGDTI 412
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESK--QSAQGDT 124
R + VY C A+N YG A V VL E R L P + Q
Sbjct: 413 IFSNVQER---SSAVYQCNASNEYGYLL---ANAFVNVLAEPPRILTPANTLYQVIANRP 466
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD----------ARQTD 174
+L+C GSP P + W K + D + L + G L I+D A++
Sbjct: 467 ALLDC-AFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIKDATWIVKEIPVAQKDS 524
Query: 175 AGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD-- 232
G Y C+ARN G +A ++H++ PE V Q GS V+F+C+V D
Sbjct: 525 TGTYTCVARNKLG-----MAKNEVHLQ------PEYAVVQRGSMVSFECKVKHDHTLSLT 573
Query: 233 VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
VLW + +P +D L + +V D G Y+C A ++ +VSAS L+V P
Sbjct: 574 VLWLKD--NRELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVAP 631
Score = 80.2 bits (189), Expect = 4e-14
Identities = 182/818 (22%), Positives = 307/818 (37%), Gaps = 97/818 (11%)
Query: 30 TLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
+L C A G P+P I W K G+L + T L+ H +D+G Y C A
Sbjct: 284 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEK----TLQIIHVS-EADSGNYQCIAK 338
Query: 89 NSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N+ G + T+ V V + + P++ + G+ L C G+P+P + W NG
Sbjct: 339 NALGAI---HHTISVRVKAAPYWITAPQNLVLSPGEDGTLIC-RANGNPKPRISWLTNGV 394
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
+ D +DG ++ + ++ + YQC A N G A A + + +P I
Sbjct: 395 PIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL-LANAFVNVLAEPPRILT 453
Query: 208 PEDVVAQ--TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL-DNVIL 264
P + + Q C G PLP + W + A G + + ++G+L + D +
Sbjct: 454 PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIKDATWI 513
Query: 265 ADE---------GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
E G Y+C A N +G ++L P V+ G++ F C
Sbjct: 514 VKEIPVAQKDSTGTYTCVARNKLGMAK----------NEVHLQPEYAVVQRGSMVSFECK 563
Query: 316 A--TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
T+ W ++ NR + P R T D + V ++D D T C
Sbjct: 564 VKHDHTLSLTVLW-LKDNREL--PSDER----FTVDKDHLVVADVSD----DDSGTYTCV 612
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPI--ITNGPSNQTLP---IKSMAVFPCTAICTPEPI 428
A S L+V + P P+ + N P + L KS+ + PI
Sbjct: 613 ANTTLDSVSASAVLSVVAPTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNNSPI 672
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV-WSGALLVDSP 487
+ E E + H+ + + T V SGT T A + YV +S ++ +
Sbjct: 673 TKFIIEYEDAM--HKPGLWHHQTEV--------SGTQT-TAQLKLSPYVNYSFRVMAVNS 721
Query: 488 INPNIHFFRAADVSSLPGPPTKPITH----NVTDTSVTLSWSQNNKIGSSSILGYQVEVF 543
I ++ + + P K T ++ ++W N S+ G Q +V
Sbjct: 722 IGKSLPSEASEQYLTKASEPDKNPTAVEGLGSEPDNLEITWKPLNGFESNG-PGLQYKVS 780
Query: 544 SRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
R+ G++ + VV+A + + Y+V + Y+ V+ N G + P P
Sbjct: 781 WRQK-DGDDEWTS----VVVA---NVSKYIVSGTPTFVPYLIKVQALNDMGFA-PEPAVV 831
Query: 604 SVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEG 663
G+D + G R N++ + E + P+ K+I+ + YY +
Sbjct: 832 MGHSGEDLPMVAPG-------NVRVNVVNSTLAE-VHWDPVPLKSIRGHLQGYRIYYWKT 883
Query: 664 LFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRV 723
R +I E K + + + L ++ Y + K EG S RV
Sbjct: 884 QSSSKRNRRHI----EKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRV 939
Query: 724 AQTLDDVPDGPPINIEMFILNTT--TVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKS 781
T + VP P + I+N T ++ L+W PP NGI+T Y + ++
Sbjct: 940 FNTPEGVPSAPS---SLKIVNPTLDSLTLEWDPP--SHPNGILTEYTLKYQPINSTHELG 994
Query: 782 MVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
+ T + NL Y A+T G G
Sbjct: 995 PLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSG 1032
Score = 68.1 bits (159), Expect = 2e-10
Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
+ P I +Q P D + + + C A G P P+ W + G + D ++ P G
Sbjct: 39 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 98
Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
+ + G+ + GVY C A N G A S N + + L + +LEP + QS G
Sbjct: 99 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 156
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
++VL C PP G P P ++W N L + R+ G+L + D Y C A
Sbjct: 157 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 215
Query: 183 R 183
R
Sbjct: 216 R 216
Score = 58.4 bits (135), Expect = 1e-07
Identities = 67/305 (21%), Positives = 116/305 (38%), Gaps = 30/305 (9%)
Query: 200 IKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
++P IT P+D + ++ QC G P P W R+ ++ + + G+
Sbjct: 38 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 97
Query: 258 RLDNVILAD------EGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309
L I+++ EG Y C A N GA ++ + P + ++SG
Sbjct: 98 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 157
Query: 310 ARFTC-TATGRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAV-----FDGVTVLTI 358
C G P P +FW + + + G++ D Y + + D +
Sbjct: 158 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 217
Query: 359 NDTDKNDSRNTIVCSAVNYAG-SSFVRGKLTVT------SDDDRPPPIIT--NGPSNQTL 409
N T + I ++ + + L+ T S +RPP +T SN+
Sbjct: 218 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEE 277
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
++ C A P PII W E L +N + TL + + ++DSG Y C+A
Sbjct: 278 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 337
Query: 470 SSRHG 474
+ G
Sbjct: 338 KNALG 342
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 12/218 (5%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177
+ +V++C +G P P+ W +NG D D + + G G L+I + +T G
Sbjct: 57 ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 115
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235
YQC ARN G S ++ P + E + Q+G S+ CR G P P + W
Sbjct: 116 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 175
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEAE-NSVGAVSASGYLTVYDPP 293
++ RV +G L NV+ D E Y C A N + ++V
Sbjct: 176 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISV-KVI 234
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
S++ +++ + F + R P F + EGN
Sbjct: 235 SVDELNDTIAANLSD-TEFYGAKSSRERPPTFLTPEGN 271
>BC031063-1|AAH31063.1| 602|Homo sapiens IGSF10 protein protein.
Length = 602
Score = 126 bits (305), Expect = 4e-28
Identities = 103/381 (27%), Positives = 166/381 (43%), Gaps = 17/381 (4%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRA 71
Y + T RH +CRA G+PSP + W + + + + S + L
Sbjct: 220 YTSRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEI 279
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ-GDTVVLEC 129
+ R+ SD+ + C A N G + + +LR FR K AQ G + L C
Sbjct: 280 RNVRL-SDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNC 338
Query: 130 LPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAG 187
G+P P + W NG S +L+ G+ +I + DAG+Y+C ARN G
Sbjct: 339 -SVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVG 397
Query: 188 TRESAIATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMP 245
E + L+I KP ++T P V +G S++ C G P P++ W +G + P
Sbjct: 398 YIEK-LVILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRP 456
Query: 246 L--GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSPNS 301
G+ + D+G+L + D G Y C+A+NSVG ++ + Y P N P S
Sbjct: 457 QINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRS 516
Query: 302 VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDT 361
+ +G + C A G P+P + W + + + S+++ H + L I +
Sbjct: 517 IVTRTGAAFQLHCVALGVPKPEITWEMPDHS--LLSTASKERTHGSEQLHLQGTLVIQNP 574
Query: 362 DKNDSRNTIVCSAVNYAGSSF 382
+DS C+A N GS +
Sbjct: 575 QTSDS-GIYKCTAKNPLGSDY 594
Score = 120 bits (289), Expect = 3e-26
Identities = 120/469 (25%), Positives = 189/469 (40%), Gaps = 38/469 (8%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
A L+C G P P I W ++S R A G + D+G Y C A
Sbjct: 138 AVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK---LLDSGEYVCVA 194
Query: 88 TNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
N G + ++ + K +A + G+P P V W
Sbjct: 195 RNPSGDDTKMYKLDVVSKPPLINGLYTSRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIM 254
Query: 145 NGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA--TLKIHI 200
L SR+ + G L I++ R +D+ + C+ARN G + L++
Sbjct: 255 PDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLR 314
Query: 201 KPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLG-RVKVLDDG 255
+P P E +VAQ G S C V G+P P+++W G N P + + +G
Sbjct: 315 RP-TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 373
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVARFTC 314
S + D G+Y C A N VG + L + P I +P +V SG C
Sbjct: 374 SFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHC 433
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ G P+P + W++ + P ++ KY + D T L I + D R +C A
Sbjct: 434 VSDGIPKPNIKWTMPSGYVVDRPQIN-GKY---ILHDNGT-LVIKEATAYD-RGNYICKA 487
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTAICTPEPIIAWY 432
N G + + + + + PP ITN P +++ ++ A F C A+ P+P I W
Sbjct: 488 QNSVGHTLITVPVMIVAY----PPRITNRPP-RSIVTRTGAAFQLHCVALGVPKPEITWE 542
Query: 433 FEGEALIQNHRRNVTN-------DGTLVLKDLDKSDSGTYTCVASSRHG 474
+L+ + T+ GTLV+++ SDSG Y C A + G
Sbjct: 543 MPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 591
Score = 117 bits (282), Expect = 2e-25
Identities = 123/476 (25%), Positives = 204/476 (42%), Gaps = 52/476 (10%)
Query: 31 LNCRAGGSPSPAIRW-YKGGVLV-----VSDT-HRS----ILPAGGLFFLRATHGRVHSD 79
++C+A GSP P I W G ++ D+ HR+ + G L+F + ++
Sbjct: 37 VDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGV----AE 92
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSP 136
G Y C A N+ G + +H+ V+ R+ +K + + GDT VL+C G P
Sbjct: 93 EGDYTCYAQNTLGKDEMK---VHLTVITAAPRIRQSNKTNKRIKAGDTAVLDC-EVTGDP 148
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
+P ++W ++ R G+L I + D+G Y C+ARN +G ++ + L
Sbjct: 149 KPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSGD-DTKMYKL 207
Query: 197 KIHIKPYLITG---PEDVVAQTG---SSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--G 247
+ KP LI G V+ T S F CR G P P+V+W P
Sbjct: 208 DVVSKPPLINGLYTSRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGS 267
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVN 303
R+ V +G+L + NV L+D ++ C A N G L V + P N +
Sbjct: 268 RITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIV 327
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
+ G C+ G P P + W + N T G Y +G + I+ T +
Sbjct: 328 AQLGKSTALNCSVDGNPPPEIIW-ILPNGTRFSNG--PQSYQYLIASNGSFI--ISKTTR 382
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAI 422
D+ C+A N G ++ KL + + + P I+T P + + +S+++ C +
Sbjct: 383 EDA-GKYRCAARNKVG--YIE-KLVIL-EIGQKPVILTYAPGTVKGISGESLSLH-CVSD 436
Query: 423 CTPEPIIAWYFEGEALIQNHRRN----VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P+P I W ++ + N + ++GTLV+K+ D G Y C A + G
Sbjct: 437 GIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVG 492
Score = 99.5 bits (237), Expect = 6e-20
Identities = 86/285 (30%), Positives = 125/285 (43%), Gaps = 37/285 (12%)
Query: 216 GSSVTFQCRVGGDPLPDVLWR----------RSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
G C+ G P+P++ W A R + ++G+L + V +A
Sbjct: 32 GKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGVA 91
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDP-PSINLSPNSVN--VESGNVARFTCTATGRPEP 322
+EG+Y+C A+N++G +LTV P I S N N +++G+ A C TG P+P
Sbjct: 92 EEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQS-NKTNKRIKAGDTAVLDCEVTGDPKP 150
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
+FW + N I F + R +HA LTIN DS VC A N +G
Sbjct: 151 KIFWLLPSNDMISF-SIDRYTFHANGS------LTINKVKLLDS-GEYVCVARNPSGDDT 202
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV------FPCTAICTPEPIIAWYFEGE 436
KL V S PP+I NG IK+ AV F C A TP P + W
Sbjct: 203 KMYKLDVVSK----PPLI-NGLYTSRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDN 257
Query: 437 ALIQ----NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
+ R V +GTL ++++ SDS + CVA + G+ V
Sbjct: 258 IFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESV 302
Score = 91.9 bits (218), Expect = 1e-17
Identities = 70/273 (25%), Positives = 117/273 (42%), Gaps = 21/273 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
LNC G+P P I W S+ +++ ++ + G F + T DAG Y C A
Sbjct: 336 LNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKT---TREDAGKYRCAA 392
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + L + P + + G+++ L C+ G P+PN+ W
Sbjct: 393 RNKVGYIE-KLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSD-GIPKPNIKWTMPSG 450
Query: 148 TLL----FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
++ +G +H D G LVI++A D G Y C A+N+ G + + + P
Sbjct: 451 YVVDRPQINGKYILH--DNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 508
Query: 204 LITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SAGGGNMPLGRVKVLDDGS 256
+ P +V +TG++ C G P P++ W S G ++ G+
Sbjct: 509 ITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGT 568
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L + N +D G Y C A+N +G+ A+ Y+ V
Sbjct: 569 LVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 601
Score = 58.4 bits (135), Expect = 1e-07
Identities = 54/195 (27%), Positives = 82/195 (42%), Gaps = 17/195 (8%)
Query: 9 GEAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAG 64
G+ P I+ P V + +L+C + G P P I+W VV + IL
Sbjct: 408 GQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDN 467
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G ++ D G Y C+A NS G + VA P S + G
Sbjct: 468 GTLVIKEATAY---DRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAA 524
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFD-------GDSRMHLVDGGNLVIQDARQTDAGR 177
L C+ G P+P + W+ +LL G ++HL G LVIQ+ + +D+G
Sbjct: 525 FQLHCVA-LGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQ--GTLVIQNPQTSDSGI 581
Query: 178 YQCIARNAAGTRESA 192
Y+C A+N G+ +A
Sbjct: 582 YKCTAKNPLGSDYAA 596
>BC045734-1|AAH45734.1| 442|Homo sapiens IGSF10 protein protein.
Length = 442
Score = 126 bits (304), Expect = 5e-28
Identities = 102/375 (27%), Positives = 165/375 (44%), Gaps = 17/375 (4%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
+ T RH +CRA G+PSP + W + + + + S + L + R+
Sbjct: 66 IKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRL- 124
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ-GDTVVLECLPPRGS 135
SD+ + C A N G + + +LR FR K AQ G + L C G+
Sbjct: 125 SDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNC-SVDGN 183
Query: 136 PEPNVYW-KKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
P P + W NG S +L+ G+ +I + DAG+Y+C ARN G E +
Sbjct: 184 PPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEK-L 242
Query: 194 ATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--GRV 249
L+I KP ++T P V +G S++ C G P P++ W +G + P G+
Sbjct: 243 VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY 302
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSPNSVNVESG 307
+ D+G+L + D G Y C+A+NSVG ++ + Y P N P S+ +G
Sbjct: 303 ILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTG 362
Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
+ C A G P+P + W + + + S+++ H + L I + +DS
Sbjct: 363 AAFQLHCVALGVPKPEITWEMPDHS--LLSTASKERTHGSEQLHLQGTLVIQNPQTSDS- 419
Query: 368 NTIVCSAVNYAGSSF 382
C+A N GS +
Sbjct: 420 GIYKCTAKNPLGSDY 434
Score = 118 bits (283), Expect = 2e-25
Identities = 99/360 (27%), Positives = 157/360 (43%), Gaps = 31/360 (8%)
Query: 134 GSPEPNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
G+P P V W L SR+ + G L I++ R +D+ + C+ARN G
Sbjct: 84 GTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVL 143
Query: 192 AIA--TLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMP 245
+ L++ +P P E +VAQ G S C V G+P P+++W G N P
Sbjct: 144 VVQLEVLEMLRRP-TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGP 202
Query: 246 LG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVN 303
+ + +GS + D G+Y C A N VG + L + P I +P +V
Sbjct: 203 QSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVK 262
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
SG C + G P+P + W++ + P ++ KY + D T L I +
Sbjct: 263 GISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQIN-GKY---ILHDNGT-LVIKEATA 317
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTA 421
D R +C A N G + + + + + PP ITN P +++ ++ A F C A
Sbjct: 318 YD-RGNYICKAQNSVGHTLITVPVMIVA----YPPRITNRPP-RSIVTRTGAAFQLHCVA 371
Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTN-------DGTLVLKDLDKSDSGTYTCVASSRHG 474
+ P+P I W +L+ + T+ GTLV+++ SDSG Y C A + G
Sbjct: 372 LGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 431
Score = 91.9 bits (218), Expect = 1e-17
Identities = 70/273 (25%), Positives = 117/273 (42%), Gaps = 21/273 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
LNC G+P P I W S+ +++ ++ + G F + T DAG Y C A
Sbjct: 176 LNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKT---TREDAGKYRCAA 232
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + L + P + + G+++ L C+ G P+PN+ W
Sbjct: 233 RNKVGYIE-KLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSD-GIPKPNIKWTMPSG 290
Query: 148 TLL----FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
++ +G +H D G LVI++A D G Y C A+N+ G + + + P
Sbjct: 291 YVVDRPQINGKYILH--DNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 348
Query: 204 LITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SAGGGNMPLGRVKVLDDGS 256
+ P +V +TG++ C G P P++ W S G ++ G+
Sbjct: 349 ITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGT 408
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L + N +D G Y C A+N +G+ A+ Y+ V
Sbjct: 409 LVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 441
Score = 84.6 bits (200), Expect = 2e-15
Identities = 87/330 (26%), Positives = 141/330 (42%), Gaps = 30/330 (9%)
Query: 163 GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---PEDVVAQTG--- 216
G+L I + D+G Y C+ARN +G ++ + L + KP LI G V+ T
Sbjct: 15 GSLTINKVKLLDSGEYVCVARNPSGD-DTKMYKLDVVSKPPLINGLYTNRTVIKATAVRH 73
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--GRVKVLDDGSLRLDNVILADEGEYSCE 273
S F CR G P P+V+W P R+ V +G+L + NV L+D ++ C
Sbjct: 74 SKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICV 133
Query: 274 AENSVGAVSASGYLTVYD----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
A N G L V + P N + + G C+ G P P + W +
Sbjct: 134 ARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIW-IL 192
Query: 330 GNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV 389
N T G Y +G + I+ T + D+ C+A N G ++ KL +
Sbjct: 193 PNGTRFSNG--PQSYQYLIASNGSFI--ISKTTREDA-GKYRCAARNKVG--YIE-KLVI 244
Query: 390 TSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN--- 445
+ + P I+T P + + +S+++ C + P+P I W ++ + N
Sbjct: 245 L-EIGQKPVILTYAPGTVKGISGESLSLH-CVSDGIPKPNIKWTMPSGYVVDRPQINGKY 302
Query: 446 -VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+ ++GTLV+K+ D G Y C A + G
Sbjct: 303 ILHDNGTLVIKEATAYDRGNYICKAQNSVG 332
Score = 62.9 bits (146), Expect = 7e-09
Identities = 61/233 (26%), Positives = 96/233 (41%), Gaps = 21/233 (9%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSIN-LSPNSVNVESGNV-- 309
+GSL ++ V L D GEY C A N G + L V PP IN L N +++ V
Sbjct: 14 NGSLTINKVKLLDSGEYVCVARNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRH 73
Query: 310 --ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
F C A G P P + W + N IF ++ Y + L I + +DS
Sbjct: 74 SKKHFDCRAEGTPSPEVMWIMPDN---IF--LTAPYYGSRITVHKNGTLEIRNVRLSDSA 128
Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL--PIKSMAVFPCTAICTP 425
+ +C A N G S + +L V RP P N+ + + C+ P
Sbjct: 129 D-FICVARNEGGESVLVVQLEVLEMLRRP---TFRNPFNEKIVAQLGKSTALNCSVDGNP 184
Query: 426 EPIIAWYFEGEALI----QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P I W Q+++ + ++G+ ++ + D+G Y C A ++ G
Sbjct: 185 PPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVG 237
Score = 58.4 bits (135), Expect = 1e-07
Identities = 54/195 (27%), Positives = 82/195 (42%), Gaps = 17/195 (8%)
Query: 9 GEAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAG 64
G+ P I+ P V + +L+C + G P P I+W VV + IL
Sbjct: 248 GQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDN 307
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G ++ D G Y C+A NS G + VA P S + G
Sbjct: 308 GTLVIKEATAY---DRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAA 364
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFD-------GDSRMHLVDGGNLVIQDARQTDAGR 177
L C+ G P+P + W+ +LL G ++HL G LVIQ+ + +D+G
Sbjct: 365 FQLHCVA-LGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQ--GTLVIQNPQTSDSGI 421
Query: 178 YQCIARNAAGTRESA 192
Y+C A+N G+ +A
Sbjct: 422 YKCTAKNPLGSDYAA 436
Score = 48.8 bits (111), Expect = 1e-04
Identities = 44/132 (33%), Positives = 60/132 (45%), Gaps = 16/132 (12%)
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
LTIN DS VC A N +G KL V S PP+I +N+T+ IK+ A
Sbjct: 17 LTINKVKLLDS-GEYVCVARNPSGDDTKMYKLDVVSK----PPLINGLYTNRTV-IKATA 70
Query: 416 V------FPCTAICTPEPIIAWYFEGEALIQ----NHRRNVTNDGTLVLKDLDKSDSGTY 465
V F C A TP P + W + R V +GTL ++++ SDS +
Sbjct: 71 VRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADF 130
Query: 466 TCVASSRHGKYV 477
CVA + G+ V
Sbjct: 131 ICVARNEGGESV 142
>AK098838-1|BAC05429.1| 399|Homo sapiens protein ( Homo sapiens
cDNA FLJ25972 fis, clone TST05664. ).
Length = 399
Score = 126 bits (304), Expect = 5e-28
Identities = 102/375 (27%), Positives = 165/375 (44%), Gaps = 17/375 (4%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
+ T RH +CRA G+PSP + W + + + + S + L + R+
Sbjct: 23 IKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRL- 81
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ-GDTVVLECLPPRGS 135
SD+ + C A N G + + +LR FR K AQ G + L C G+
Sbjct: 82 SDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNC-SVDGN 140
Query: 136 PEPNVYW-KKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
P P + W NG S +L+ G+ +I + DAG+Y+C ARN G E +
Sbjct: 141 PPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEK-L 199
Query: 194 ATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--GRV 249
L+I KP ++T P V +G S++ C G P P++ W +G + P G+
Sbjct: 200 VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY 259
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSPNSVNVESG 307
+ D+G+L + D G Y C+A+NSVG ++ + Y P N P S+ +G
Sbjct: 260 ILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTG 319
Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
+ C A G P+P + W + + + S+++ H + L I + +DS
Sbjct: 320 AAFQLHCVALGVPKPEITWEMPDHS--LLSTASKERTHGSEQLHLQGTLVIQNPQTSDS- 376
Query: 368 NTIVCSAVNYAGSSF 382
C+A N GS +
Sbjct: 377 GIYKCTAKNPLGSDY 391
Score = 118 bits (283), Expect = 2e-25
Identities = 99/360 (27%), Positives = 157/360 (43%), Gaps = 31/360 (8%)
Query: 134 GSPEPNVYWKKNGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
G+P P V W L SR+ + G L I++ R +D+ + C+ARN G
Sbjct: 41 GTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVL 100
Query: 192 AIA--TLKIHIKPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMP 245
+ L++ +P P E +VAQ G S C V G+P P+++W G N P
Sbjct: 101 VVQLEVLEMLRRP-TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGP 159
Query: 246 LG-RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVN 303
+ + +GS + D G+Y C A N VG + L + P I +P +V
Sbjct: 160 QSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVK 219
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
SG C + G P+P + W++ + P ++ KY + D T L I +
Sbjct: 220 GISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQIN-GKY---ILHDNGT-LVIKEATA 274
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTA 421
D R +C A N G + + + + + PP ITN P +++ ++ A F C A
Sbjct: 275 YD-RGNYICKAQNSVGHTLITVPVMIVA----YPPRITNRPP-RSIVTRTGAAFQLHCVA 328
Query: 422 ICTPEPIIAWYFEGEALIQNHRRNVTN-------DGTLVLKDLDKSDSGTYTCVASSRHG 474
+ P+P I W +L+ + T+ GTLV+++ SDSG Y C A + G
Sbjct: 329 LGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 388
Score = 91.9 bits (218), Expect = 1e-17
Identities = 70/273 (25%), Positives = 117/273 (42%), Gaps = 21/273 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
LNC G+P P I W S+ +++ ++ + G F + T DAG Y C A
Sbjct: 133 LNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKT---TREDAGKYRCAA 189
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + L + P + + G+++ L C+ G P+PN+ W
Sbjct: 190 RNKVGYIE-KLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSD-GIPKPNIKWTMPSG 247
Query: 148 TLL----FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
++ +G +H D G LVI++A D G Y C A+N+ G + + + P
Sbjct: 248 YVVDRPQINGKYILH--DNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 305
Query: 204 LITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SAGGGNMPLGRVKVLDDGS 256
+ P +V +TG++ C G P P++ W S G ++ G+
Sbjct: 306 ITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGT 365
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L + N +D G Y C A+N +G+ A+ Y+ V
Sbjct: 366 LVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 398
Score = 58.4 bits (135), Expect = 1e-07
Identities = 54/195 (27%), Positives = 82/195 (42%), Gaps = 17/195 (8%)
Query: 9 GEAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH---RSILPAG 64
G+ P I+ P V + +L+C + G P P I+W VV + IL
Sbjct: 205 GQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKYILHDN 264
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G ++ D G Y C+A NS G + VA P S + G
Sbjct: 265 GTLVIKEATAY---DRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTGAA 321
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFD-------GDSRMHLVDGGNLVIQDARQTDAGR 177
L C+ G P+P + W+ +LL G ++HL G LVIQ+ + +D+G
Sbjct: 322 FQLHCVA-LGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQ--GTLVIQNPQTSDSGI 378
Query: 178 YQCIARNAAGTRESA 192
Y+C A+N G+ +A
Sbjct: 379 YKCTAKNPLGSDYAA 393
Score = 40.3 bits (90), Expect = 0.041
Identities = 29/91 (31%), Positives = 44/91 (48%), Gaps = 11/91 (12%)
Query: 397 PPIITNGPSNQTLPIKSMAV------FPCTAICTPEPIIAWYFEGEALIQ----NHRRNV 446
PP+I +N+T+ IK+ AV F C A TP P + W + R V
Sbjct: 10 PPLINGLYTNRTV-IKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITV 68
Query: 447 TNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
+GTL ++++ SDS + CVA + G+ V
Sbjct: 69 HKNGTLEIRNVRLSDSADFICVARNEGGESV 99
>AK093069-1|BAC04042.1| 650|Homo sapiens protein ( Homo sapiens
cDNA FLJ35750 fis, clone TESTI2004539, weakly similar to
Homo sapiens adlican mRNA. ).
Length = 650
Score = 126 bits (304), Expect = 5e-28
Identities = 102/375 (27%), Positives = 165/375 (44%), Gaps = 17/375 (4%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
+ T RH +CRA G+PSP + W + + + + S + L + R+
Sbjct: 274 IKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGSRITVHKNGTLEIRNVRL- 332
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQ-GDTVVLECLPPRGS 135
SD+ + C A N G + + +LR FR K AQ G + L C G+
Sbjct: 333 SDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIVAQLGKSTALNC-SVDGN 391
Query: 136 PEPNVYW-KKNGQTLLFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
P P + W NG S +L+ G+ +I + DAG+Y+C ARN G E +
Sbjct: 392 PPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKTTREDAGKYRCAARNKVGYIEK-L 450
Query: 194 ATLKIHIKPYLIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--GRV 249
L+I KP ++T P V +G S++ C G P P++ W +G + P G+
Sbjct: 451 VILEIGQKPVILTYAPGTVKGISGESLSLHCVSDGIPKPNIKWTMPSGYVVDRPQINGKY 510
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVG--AVSASGYLTVYDPPSINLSPNSVNVESG 307
+ D+G+L + D G Y C+A+NSVG ++ + Y P N P S+ +G
Sbjct: 511 ILHDNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPRITNRPPRSIVTRTG 570
Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
+ C A G P+P + W + + + S+++ H + L I + +DS
Sbjct: 571 AAFQLHCVALGVPKPEITWEMPDHS--LLSTASKERTHGSEQLHLQGTLVIQNPQTSDS- 627
Query: 368 NTIVCSAVNYAGSSF 382
C+A N GS +
Sbjct: 628 GIYKCTAKNPLGSDY 642
Score = 122 bits (293), Expect = 1e-26
Identities = 103/348 (29%), Positives = 157/348 (45%), Gaps = 40/348 (11%)
Query: 155 SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ 214
S +H+ G+L I + D+G Y C+ARN G + + + + +KP I + Q
Sbjct: 18 SWIHVYPNGSLFIGSVTEKDSGVYLCVARNKMGD-DLILMHVSLRLKPAKIDHKQYFRKQ 76
Query: 215 T--GSSVTFQCRVGGDPLPDVLW----------RRSAGGGNMPLGRVKVLDDGSLRLDNV 262
G C+ G P+P++ W A R + ++G+L + V
Sbjct: 77 VLHGKDFQVDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKV 136
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLSPNSVN--VESGNVARFTCTATGR 319
+A+EG+Y+C A+N++G +LTV P I S N N +++G+ A C TG
Sbjct: 137 GVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQS-NKTNKRIKAGDTAVLDCEVTGD 195
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
P+P +FW + N I F + R +HA LTIN DS VC A N +G
Sbjct: 196 PKPKIFWLLPSNDMISF-SIDRYTFHANG------SLTINKVKLLDS-GEYVCVARNPSG 247
Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV------FPCTAICTPEPIIAWYF 433
KL V S PP+I +N+T+ IK+ AV F C A TP P + W
Sbjct: 248 DDTKMYKLDVVS----KPPLINGLYTNRTV-IKATAVRHSKKHFDCRAEGTPSPEVMWIM 302
Query: 434 EGEALI----QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
+ R V +GTL ++++ SDS + CVA + G+ V
Sbjct: 303 PDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESV 350
Score = 120 bits (288), Expect = 4e-26
Identities = 120/469 (25%), Positives = 189/469 (40%), Gaps = 38/469 (8%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVS-DTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
A L+C G P P I W ++S R A G + D+G Y C A
Sbjct: 186 AVLDCEVTGDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVK---LLDSGEYVCVA 242
Query: 88 TNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
N G + ++ + K +A + G+P P V W
Sbjct: 243 RNPSGDDTKMYKLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIM 302
Query: 145 NGQTLLFDG--DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA--TLKIHI 200
L SR+ + G L I++ R +D+ + C+ARN G + L++
Sbjct: 303 PDNIFLTAPYYGSRITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLR 362
Query: 201 KPYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLG-RVKVLDDG 255
+P P E +VAQ G S C V G+P P+++W G N P + + +G
Sbjct: 363 RP-TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNG 421
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-NLSPNSVNVESGNVARFTC 314
S + D G+Y C A N VG + L + P I +P +V SG C
Sbjct: 422 SFIISKTTREDAGKYRCAARNKVGYIEKLVILEIGQKPVILTYAPGTVKGISGESLSLHC 481
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
+ G P+P + W++ + P ++ KY + D T L I + D R +C A
Sbjct: 482 VSDGIPKPNIKWTMPSGYVVDRPQIN-GKY---ILHDNGT-LVIKEATAYD-RGNYICKA 535
Query: 375 VNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTAICTPEPIIAWY 432
N G + + + + + PP ITN P +++ ++ A F C A+ P+P I W
Sbjct: 536 QNSVGHTLITVPVMIVAY----PPRITNRPP-RSIVTRTGAAFQLHCVALGVPKPEITWE 590
Query: 433 FEGEALIQNHRRNVTN-------DGTLVLKDLDKSDSGTYTCVASSRHG 474
+L+ + T+ GTLV+++ SDSG Y C A + G
Sbjct: 591 MPDHSLLSTASKERTHGSEQLHLQGTLVIQNPQTSDSGIYKCTAKNPLG 639
Score = 117 bits (281), Expect = 3e-25
Identities = 123/476 (25%), Positives = 204/476 (42%), Gaps = 52/476 (10%)
Query: 31 LNCRAGGSPSPAIRW-YKGGVLV-----VSDT-HRS----ILPAGGLFFLRATHGRVHSD 79
++C+A GSP P I W G ++ D+ HR+ + G L+F + ++
Sbjct: 85 VDCKASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYFNKVGV----AE 140
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---GDTVVLECLPPRGSP 136
G Y C A N+ G + +H+ V+ R+ +K + + GDT VL+C G P
Sbjct: 141 EGDYTCYAQNTLGKDEMK---VHLTVITAAPRIRQSNKTNKRIKAGDTAVLDC-EVTGDP 196
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
+P ++W ++ R G+L I + D+G Y C+ARN +G ++ + L
Sbjct: 197 KPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSGD-DTKMYKL 255
Query: 197 KIHIKPYLITG---PEDVVAQTG---SSVTFQCRVGGDPLPDVLWRRSAG-GGNMPL--G 247
+ KP LI G V+ T S F CR G P P+V+W P
Sbjct: 256 DVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDNIFLTAPYYGS 315
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----PPSINLSPNSVN 303
R+ V +G+L + NV L+D ++ C A N G L V + P N +
Sbjct: 316 RITVHKNGTLEIRNVRLSDSADFICVARNEGGESVLVVQLEVLEMLRRPTFRNPFNEKIV 375
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
+ G C+ G P P + W + N T G Y +G + I+ T +
Sbjct: 376 AQLGKSTALNCSVDGNPPPEIIW-ILPNGTRFSNG--PQSYQYLIASNGSFI--ISKTTR 430
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN-QTLPIKSMAVFPCTAI 422
D+ C+A N G ++ KL + + + P I+T P + + +S+++ C +
Sbjct: 431 EDA-GKYRCAARNKVG--YIE-KLVIL-EIGQKPVILTYAPGTVKGISGESLSLH-CVSD 484
Query: 423 CTPEPIIAWYFEGEALIQNHRRN----VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P+P I W ++ + N + ++GTLV+K+ D G Y C A + G
Sbjct: 485 GIPKPNIKWTMPSGYVVDRPQINGKYILHDNGTLVIKEATAYDRGNYICKAQNSVG 540
Score = 105 bits (251), Expect = 1e-21
Identities = 110/441 (24%), Positives = 174/441 (39%), Gaps = 43/441 (9%)
Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES--- 116
+ P G LF T D+GVY C A N G +HV++ + +++ +
Sbjct: 22 VYPNGSLFIGSVTE----KDSGVYLCVARNKMG---DDLILMHVSLRLKPAKIDHKQYFR 74
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG----DS-----RMHLVDGGNLVI 167
KQ G ++C GSP P + W T++ + DS R L + G L
Sbjct: 75 KQVLHGKDFQVDC-KASGSPVPEISWSLPDGTMINNAMQADDSGHRTRRYTLFNNGTLYF 133
Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL-ITGPEDVVAQTGSSVTFQCRVG 226
+ G Y C A+N G E + I P + + + + G + C V
Sbjct: 134 NKVGVAEEGDYTCYAQNTLGKDEMKVHLTVITAAPRIRQSNKTNKRIKAGDTAVLDCEVT 193
Query: 227 GDPLPDVLWRRSAGGG-NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG 285
GDP P + W + + + R +GSL ++ V L D GEY C A N G +
Sbjct: 194 GDPKPKIFWLLPSNDMISFSIDRYTFHANGSLTINKVKLLDSGEYVCVARNPSGDDTKMY 253
Query: 286 YLTVYD-PPSIN-LSPNSVNVESGNV----ARFTCTATGRPEPTMFWSVEGNRTIIFPGM 339
L V PP IN L N +++ V F C A G P P + W + N IF +
Sbjct: 254 KLDVVSKPPLINGLYTNRTVIKATAVRHSKKHFDCRAEGTPSPEVMWIMPDN---IF--L 308
Query: 340 SRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
+ Y + L I + +DS + +C A N G S + +L V RP
Sbjct: 309 TAPYYGSRITVHKNGTLEIRNVRLSDSAD-FICVARNEGGESVLVVQLEVLEMLRRP--- 364
Query: 400 ITNGPSNQTL--PIKSMAVFPCTAICTPEPIIAWYFEGEALI----QNHRRNVTNDGTLV 453
P N+ + + C+ P P I W Q+++ + ++G+ +
Sbjct: 365 TFRNPFNEKIVAQLGKSTALNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFI 424
Query: 454 LKDLDKSDSGTYTCVASSRHG 474
+ + D+G Y C A ++ G
Sbjct: 425 ISKTTREDAGKYRCAARNKVG 445
Score = 91.9 bits (218), Expect = 1e-17
Identities = 70/273 (25%), Positives = 117/273 (42%), Gaps = 21/273 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSD---THRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
LNC G+P P I W S+ +++ ++ + G F + T DAG Y C A
Sbjct: 384 LNCSVDGNPPPEIIWILPNGTRFSNGPQSYQYLIASNGSFIISKT---TREDAGKYRCAA 440
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + L + P + + G+++ L C+ G P+PN+ W
Sbjct: 441 RNKVGYIE-KLVILEIGQKPVILTYAPGTVKGISGESLSLHCVSD-GIPKPNIKWTMPSG 498
Query: 148 TLL----FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
++ +G +H D G LVI++A D G Y C A+N+ G + + + P
Sbjct: 499 YVVDRPQINGKYILH--DNGTLVIKEATAYDRGNYICKAQNSVGHTLITVPVMIVAYPPR 556
Query: 204 LIT-GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR------SAGGGNMPLGRVKVLDDGS 256
+ P +V +TG++ C G P P++ W S G ++ G+
Sbjct: 557 ITNRPPRSIVTRTGAAFQLHCVALGVPKPEITWEMPDHSLLSTASKERTHGSEQLHLQGT 616
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L + N +D G Y C A+N +G+ A+ Y+ V
Sbjct: 617 LVIQNPQTSDSGIYKCTAKNPLGSDYAATYIQV 649
>AB052622-1|BAB86306.1| 1250|Homo sapiens hDDM36 protein.
Length = 1250
Score = 126 bits (304), Expect = 5e-28
Identities = 102/338 (30%), Positives = 151/338 (44%), Gaps = 32/338 (9%)
Query: 18 PLDVTVARHQPATLNCRAGGS---PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR--AT 72
PL V + Q A LNC G + P + W K G ++ H +LP G L+ + A
Sbjct: 42 PLQVILGPEQAAVLNCSLGAAAAGPPTRVTWSKDGDTLLEHDHLHLLPNGSLWLSQPLAP 101
Query: 73 HGRVHS--DA-----GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+G S +A G Y C A G S+ A + +A L + F L PES+ + T
Sbjct: 102 NGSDESVPEAVGVIEGNYSCLAHGPLGVLASQTAVVKLATLAD-FSLHPESQTVEENGTA 160
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
EC G P P + W+K+ TL + R+ ++ G L I D +++DAG Y+C+A N+
Sbjct: 161 RFEC-HIEGLPAPIITWEKDQVTL--PEEPRLIVLPNGVLQILDVQESDAGPYRCVATNS 217
Query: 186 AGTRESAIATLKIHIKPYL----------ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
A S A L + + L + PE+ +G SV +C DP P V W
Sbjct: 218 ARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSW 277
Query: 236 RRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAEN--SVGAVSASGYLTVYDP 292
R G P+ V VL +L + N G Y C A + +A+ L V
Sbjct: 278 VRQDG---KPISTDVIVLGRTNLLIANAQPWHSGVYVCRANKPRTRDFATAAAELRVLAA 334
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
P+I +P +++ + ARF C A+G P P + W G
Sbjct: 335 PAITQAPEALSRTRASTARFVCRASGEPRPALRWLHNG 372
Score = 112 bits (269), Expect = 8e-24
Identities = 95/298 (31%), Positives = 135/298 (45%), Gaps = 24/298 (8%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P TV + A C G P+P I W K V + + +LP G L L
Sbjct: 149 PESQTVEENGTARFECHIEGLPAPIITWEKDQVTLPEEPRLIVLPNGVLQILDVQE---- 204
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVA-------VLREEFRL--EPESKQSAQGDTVVLE 128
SDAG Y C ATNS S+ A L VA ++ + PE+ G +VV+E
Sbjct: 205 SDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRGQDVVIVAAPENTTVVSGQSVVME 264
Query: 129 CLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C+ P P V W +++G+ + D + ++ NL+I +A+ +G Y C A N
Sbjct: 265 CVAS-ADPTPFVSWVRQDGKPISTD----VIVLGRTNLLIANAQPWHSGVYVCRA-NKPR 318
Query: 188 TRE--SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
TR+ +A A L++ P + PE + S+ F CR G+P P + W + G P
Sbjct: 319 TRDFATAAAELRVLAAPAITQAPEALSRTRASTARFVCRASGEPRPALRWLHN-GAPLRP 377
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
GRVKV G SL + + L D G Y C AENS G A+ L V + +P V
Sbjct: 378 NGRVKVQGGGGSLVITQIGLQDAGYYQCVAENSAGMACAAASLAVVVREGLPSAPTRV 435
Score = 86.6 bits (205), Expect = 5e-16
Identities = 108/431 (25%), Positives = 162/431 (37%), Gaps = 58/431 (13%)
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--------DARQTDA-----GRYQCIA 182
P V W K+G TLL +HL+ G+L + D +A G Y C+A
Sbjct: 66 PPTRVTWSKDGDTLL--EHDHLHLLPNGSLWLSQPLAPNGSDESVPEAVGVIEGNYSCLA 123
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
G S A +K+ PE + + F+C + G P P + W +
Sbjct: 124 HGPLGVLASQTAVVKLATLADFSLHPESQTVEENGTARFECHIEGLPAPIITWEKDQ--V 181
Query: 243 NMP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPS------ 294
+P R+ VL +G L++ +V +D G Y C A NS S L+V S
Sbjct: 182 TLPEEPRLIVLPNGVLQILDVQESDAGPYRCVATNSARQHFSQEALLSVAHRGSLASTRG 241
Query: 295 ----INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
I +P + V SG C A+ P P + W + + I S D +
Sbjct: 242 QDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPI-----STD-----VIV 291
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G T L I + S VC A F + P IT P +
Sbjct: 292 LGRTNLLIANAQPWHS-GVYVCRANKPRTRDFATAAAELRV---LAAPAITQAPEALSRT 347
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVA 469
S A F C A P P + W G L N R V G+LV+ + D+G Y CVA
Sbjct: 348 RASTARFVCRASGEPRPALRWLHNGAPLRPNGRVKVQGGGGSLVITQIGLQDAGYYQCVA 407
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+ G + +L V LP PT+ ++ ++V ++W + +
Sbjct: 408 ENSAGMACAAASLAV-------------VVREGLPSAPTRVTATPLSSSAVLVAW-ERPE 453
Query: 530 IGSSSILGYQV 540
+ S I+G+ +
Sbjct: 454 MHSEQIIGFSL 464
Score = 73.7 bits (173), Expect = 4e-12
Identities = 64/213 (30%), Positives = 90/213 (42%), Gaps = 10/213 (4%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
T G+ I+ P + TV Q + C A P+P + W + +S ++ G
Sbjct: 239 TRGQDVVIVAAPENTTVVSGQSVVMECVASADPTPFVSWVRQDGKPIST---DVIVLGRT 295
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTV 125
L A HS GVY C A N T A + VL + PE+ + T
Sbjct: 296 NLLIANAQPWHS--GVYVCRA-NKPRTRDFATAAAELRVLAAPAITQAPEALSRTRASTA 352
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
C G P P + W NG L +G ++ GG+LVI DAG YQC+A N+
Sbjct: 353 RFVCRAS-GEPRPALRWLHNGAPLRPNGRVKVQ-GGGGSLVITQIGLQDAGYYQCVAENS 410
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
AG A A+L + ++ L + P V A SS
Sbjct: 411 AG-MACAAASLAVVVREGLPSAPTRVTATPLSS 442
Score = 67.3 bits (157), Expect = 3e-10
Identities = 50/199 (25%), Positives = 89/199 (44%), Gaps = 17/199 (8%)
Query: 639 IEATPIDSKTIKLMWEILNFY--YLEGLFIYF---RPLDNITIEYEMKTILHSNDVSGFE 693
+ ATP+ S + + WE + + G +++ R +DN+ EY+ +ND + +
Sbjct: 435 VTATPLSSSAVLVAWERPEMHSEQIIGFSLHYQKARGMDNV--EYQFAV---NNDTTELQ 489
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+ L T YEF+++ + + + S + TLDDVP P + + N + + + W
Sbjct: 490 VRDLEPNTDYEFYVVAYSQLGASRTSTPALVHTLDDVPSAAP-QLSLSSPNPSDIRVAWL 548
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH-QATSLIMTNLTSGVSYSVQIAA 812
P L NG + Y + + K +T V T L++ +L Y V+I+A
Sbjct: 549 PLPPSLSNGQVVKYKI-----EYGLGKEDQIFSTEVRGNETQLMLNSLQPNKVYRVRISA 603
Query: 813 ETIIGLGPFSQKVYFNIDS 831
T G G SQ ++ S
Sbjct: 604 GTAAGFGAPSQWMHHRTPS 622
Score = 52.0 bits (119), Expect = 1e-05
Identities = 38/130 (29%), Positives = 56/130 (43%), Gaps = 3/130 (2%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
I L+ +TKYEF + +G + TL D P PP ++ + L +TV L W
Sbjct: 810 IGGLKPFTKYEFAVQSHGVDMDGPFGSVVERSTLPDRPSTPPSDLRLSPLTPSTVRLHWC 869
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAE 813
PP NG I Y ++ + + TT S + L S Y ++ A
Sbjct: 870 PP--TEPNGEIVEYLILYSSNHTQPEHQWTLL-TTQGNIFSAEVHGLESDTRYFFKMGAR 926
Query: 814 TIIGLGPFSQ 823
T +G GPFS+
Sbjct: 927 TEVGPGPFSR 936
>BC104812-1|AAI04813.1| 1501|Homo sapiens protein tyrosine
phosphatase, receptor type, S protein.
Length = 1501
Score = 122 bits (294), Expect = 8e-27
Identities = 158/612 (25%), Positives = 238/612 (38%), Gaps = 67/612 (10%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFF 68
E P I++P D A+ C+A G P P + W K G V S +I
Sbjct: 31 EPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 90
Query: 69 LRATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFR---LEPESKQSAQGD 123
LR R D VY C A NS G T ++ L L F + P+ K +
Sbjct: 91 LRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTR 150
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
T + C G+P+P + W K+ + + R+ + G L I+ + +TD G+Y+C+A
Sbjct: 151 TATMLCAAS-GNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVA 209
Query: 183 RNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
N+AG R S+ A L + ++ P P G +V C G P+P V W + A
Sbjct: 210 TNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGA 269
Query: 240 GG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
+MP+GR L L +V D Y+C A +S+G + A +TV P
Sbjct: 270 EDLTPEDDMPVGR------NVLELTDV--KDSANYTCVAMSSLGVIEAVAQITVKSLPK- 320
Query: 296 NLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+P + V T T +G P+P ++ +E + S+D + T
Sbjct: 321 --APGTPMVTENTATSITITWDSGNPDPVSYYVIE------YKSKSQDGPYQIKEDITTT 372
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
+I N S I SAVN G + VT ++ P + L +M
Sbjct: 373 RYSIGGLSPN-SEYEIWVSAVNSIGQG-PPSESVVTRTGEQAPASAPRNVQARMLSATTM 430
Query: 415 AVFPCTAICTPEPIIAWY-----FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
V P +I Y E E + N +++ +D L D TYT
Sbjct: 431 IV-QWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDE-TYTV-- 486
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
V + + D P++ I + +PG P ++TS+TLSWS +
Sbjct: 487 ------RVLAFTSVGDGPLSDPI---QVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ 537
Query: 530 IGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRT 589
SI+ Y E+ RE G R T YVV+ L P Y F +
Sbjct: 538 ---ESIIKY--ELLFREGDHGREVGRTFD---------PTTSYVVEDLKPNTEYAFRLAA 583
Query: 590 ENSHGLSGPSPV 601
+ GL +PV
Sbjct: 584 RSPQGLGAFTPV 595
Score = 103 bits (247), Expect = 4e-21
Identities = 161/670 (24%), Positives = 255/670 (38%), Gaps = 90/670 (13%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P I P+D + +G +F C+ GDP P V W + N D+ + LR
Sbjct: 33 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 259 LDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNVA 310
+ + DE Y C A+NSVG ++ LTV P+I++ P VE A
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
C A+G P+P + W + + P S + G L I +++ D +
Sbjct: 153 TMLCAASGNPDPEITWFKDF--LPVDPSASNGRIKQLR--SGA--LQIESSEETD-QGKY 205
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
C A N AG + P S++ +P ++ + C A+ +P P +
Sbjct: 206 ECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNI-TCVAVGSPMPYVK 264
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
W E L V G VL+ D DS YTCVA S G
Sbjct: 265 WMQGAEDLTPEDDMPV---GRNVLELTDVKDSANYTCVAMSSLGV--------------- 306
Query: 491 NIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSG 550
I V SLP P P+ T TS+T++W N + Y +E S+
Sbjct: 307 -IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNP---DPVSYYVIEYKSK----- 357
Query: 551 NNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
+ G I + T Y + L P Y V NS G GP S G+
Sbjct: 358 -----SQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIG-QGPPSESVVTRTGEQ 411
Query: 611 SNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRP 670
+ + + + R T IV+ E P++ + + + +Y +E P
Sbjct: 412 APA-----SAPRNVQARMLSATTMIVQWEE--PVEPNGLIRGYRV--YYTMEPE----HP 458
Query: 671 LDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV 730
+ N ++ + +D + SL + Y ++ F +G S+ +T V
Sbjct: 459 VGN----WQKHNV---DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGV 511
Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
P G P+N+ + T++ L WSPP Q II Y ++ D + T
Sbjct: 512 P-GQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFREGDHGRE-----VGRTFD 561
Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSI 850
TS ++ +L Y+ ++AA + GLG F+ V R L +S P N +V +
Sbjct: 562 PTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV------RQRTLQSIS--PKNFKVKM 613
Query: 851 VAGDFVMETW 860
+ V+ +W
Sbjct: 614 IMKTSVLLSW 623
>AB209333-1|BAD92570.1| 1560|Homo sapiens protein tyrosine
phosphatase, receptor type, sigma isoform 3 precursor
variant protein.
Length = 1560
Score = 122 bits (294), Expect = 8e-27
Identities = 158/612 (25%), Positives = 238/612 (38%), Gaps = 67/612 (10%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFF 68
E P I++P D A+ C+A G P P + W K G V S +I
Sbjct: 57 EPPRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 116
Query: 69 LRATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFR---LEPESKQSAQGD 123
LR R D VY C A NS G T ++ L L F + P+ K +
Sbjct: 117 LRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTR 176
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
T + C G+P+P + W K+ + + R+ + G L I+ + +TD G+Y+C+A
Sbjct: 177 TATMLCAAS-GNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVA 235
Query: 183 RNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
N+AG R S+ A L + ++ P P G +V C G P+P V W + A
Sbjct: 236 TNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGA 295
Query: 240 GG----GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
+MP+GR L L +V D Y+C A +S+G + A +TV P
Sbjct: 296 EDLTPEDDMPVGR------NVLELTDV--KDSANYTCVAMSSLGVIEAVAQITVKSLPK- 346
Query: 296 NLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+P + V T T +G P+P ++ +E + S+D + T
Sbjct: 347 --APGTPMVTENTATSITITWDSGNPDPVSYYVIE------YKSKSQDGPYQIKEDITTT 398
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
+I N S I SAVN G + VT ++ P + L +M
Sbjct: 399 RYSIGGLSPN-SEYEIWVSAVNSIGQG-PPSESVVTRTGEQAPASAPRNVQARMLSATTM 456
Query: 415 AVFPCTAICTPEPIIAWY-----FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
V P +I Y E E + N +++ +D L D TYT
Sbjct: 457 IV-QWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDE-TYTV-- 512
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
V + + D P++ I + +PG P ++TS+TLSWS +
Sbjct: 513 ------RVLAFTSVGDGPLSDPI---QVKTQQGVPGQPMNLRAEARSETSITLSWSPPRQ 563
Query: 530 IGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRT 589
SI+ Y E+ RE G R T YVV+ L P Y F +
Sbjct: 564 ---ESIIKY--ELLFREGDHGREVGRTFD---------PTTSYVVEDLKPNTEYAFRLAA 609
Query: 590 ENSHGLSGPSPV 601
+ GL +PV
Sbjct: 610 RSPQGLGAFTPV 621
Score = 103 bits (247), Expect = 4e-21
Identities = 161/670 (24%), Positives = 255/670 (38%), Gaps = 90/670 (13%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P I P+D + +G +F C+ GDP P V W + N D+ + LR
Sbjct: 59 PRFIKEPKDQIGVSGGVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 118
Query: 259 LDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNVA 310
+ + DE Y C A+NSVG ++ LTV P+I++ P VE A
Sbjct: 119 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 178
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
C A+G P+P + W + + P S + G L I +++ D +
Sbjct: 179 TMLCAASGNPDPEITWFKDF--LPVDPSASNGRIKQLR--SGA--LQIESSEETD-QGKY 231
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
C A N AG + P S++ +P ++ + C A+ +P P +
Sbjct: 232 ECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNI-TCVAVGSPMPYVK 290
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
W E L V G VL+ D DS YTCVA S G
Sbjct: 291 WMQGAEDLTPEDDMPV---GRNVLELTDVKDSANYTCVAMSSLGV--------------- 332
Query: 491 NIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSG 550
I V SLP P P+ T TS+T++W N + Y +E S+
Sbjct: 333 -IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNP---DPVSYYVIEYKSK----- 383
Query: 551 NNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
+ G I + T Y + L P Y V NS G GP S G+
Sbjct: 384 -----SQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIG-QGPPSESVVTRTGEQ 437
Query: 611 SNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRP 670
+ + + + R T IV+ E P++ + + + +Y +E P
Sbjct: 438 APA-----SAPRNVQARMLSATTMIVQWEE--PVEPNGLIRGYRV--YYTMEPE----HP 484
Query: 671 LDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDV 730
+ N ++ + +D + SL + Y ++ F +G S+ +T V
Sbjct: 485 VGN----WQKHNV---DDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGV 537
Query: 731 PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVH 790
P G P+N+ + T++ L WSPP Q II Y ++ D + T
Sbjct: 538 P-GQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFREGDHGRE-----VGRTFD 587
Query: 791 QATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSI 850
TS ++ +L Y+ ++AA + GLG F+ V R L +S P N +V +
Sbjct: 588 PTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV------RQRTLQSIS--PKNFKVKM 639
Query: 851 VAGDFVMETW 860
+ V+ +W
Sbjct: 640 IMKTSVLLSW 649
>X16841-1|CAA34739.1| 761|Homo sapiens protein ( Human mRNA for a
nontransmembrane isoform of N-CAM from skeletal muscle.
).
Length = 761
Score = 122 bits (293), Expect = 1e-26
Identities = 111/429 (25%), Positives = 177/429 (41%), Gaps = 28/429 (6%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C T G+ AT++V + ++ F+ P ++ +G+ V+ C P
Sbjct: 90 DAGIYKCVVTGEDGS--ESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLP- 146
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P + WK G+ ++ D R ++ L I+ ++TD G Y+C R A E ++
Sbjct: 147 PTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILA-RGEINFKDIQ 205
Query: 198 IHIK-PYLITGPEDVV---AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL- 252
+ + P I +++V A G SVT C G P P + W + K +
Sbjct: 206 VIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIF 265
Query: 253 -DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
DD S L + V DE EY C AEN G A+ +L V+ P I N +E
Sbjct: 266 SDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQV 325
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC A+G P P++ W R I + D + V+ LT+ D+
Sbjct: 326 TLTCEASGDPIPSITWRT-STRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDA-GEY 383
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
+C+A N G L V P+ + NQ C P I
Sbjct: 384 ICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQ-------VNITCEVFAYPSATI 436
Query: 430 AWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL- 483
+W+ +G+ L ++ N+ T L + ++D G Y C A +R G+ L+
Sbjct: 437 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQ 496
Query: 484 VDSPINPNI 492
D+P +P+I
Sbjct: 497 ADTPSSPSI 505
Score = 101 bits (241), Expect = 2e-20
Identities = 96/380 (25%), Positives = 147/380 (38%), Gaps = 30/380 (7%)
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLV----DGGNLVIQ 168
P + + G++ C + + ++ W NG+ L R+ +V L I
Sbjct: 26 PSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLT-PNQQRISVVWNDDSSSTLTIY 84
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
+A DAG Y+C+ G+ A +KI K P + G C V
Sbjct: 85 NANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSS 144
Query: 229 PLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAE-NSVGAVSASGY 286
P ++W+ + R VL + L++ + DEG Y CE + G ++
Sbjct: 145 LPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDI 204
Query: 287 LTVYD-PPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
+ + PP+I N VN + G C A G PEPTM W+ +G + I +K
Sbjct: 205 QVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQ--IEQEEDDEK 262
Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403
Y D + LTI DKND +C A N AG L V + P IT
Sbjct: 263 Y---IFSDDSSQLTIKKVDKNDEAE-YICIAENKAGEQDATIHLKVFA-----KPKITYV 313
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAW------YFEGEALIQNHR--RNVTNDGTLVLK 455
+ + ++ C A P P I W E + H R+ +L LK
Sbjct: 314 ENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLK 373
Query: 456 DLDKSDSGTYTCVASSRHGK 475
+ +D+G Y C AS+ G+
Sbjct: 374 SIQYTDAGEYICTASNTIGQ 393
Score = 73.7 bits (173), Expect = 4e-12
Identities = 111/466 (23%), Positives = 178/466 (38%), Gaps = 44/466 (9%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATHGRV 76
++ T Q TL C A G P P + W K G + D + I + T +V
Sbjct: 221 VNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS---SQLTIKKV 277
Query: 77 -HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+D Y C A N G ++AT+H+ V + E++ + + + V G
Sbjct: 278 DKNDEAEYICIAENKAG---EQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334
Query: 136 PEPNVYWKKNGQTL-----LFDGDS--RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
P P++ W+ + + + DG R H +L ++ + TDAG Y C A N G
Sbjct: 335 PIPSITWRTSTRNISSEEKTLDGHMVVRSH-ARVSSLTLKSIQYTDAGEYICTASNTIG- 392
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP--- 245
++S L++ P L GP V G+ V C V P + W R G +P
Sbjct: 393 QDSQSMYLEVQYAPKL-QGPVAVYTWEGNQVNITCEVFAYPSATISWFRD--GQLLPSSN 449
Query: 246 LGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+K+ + S V E G Y+C A N +G S L D PS SP+
Sbjct: 450 YSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPS---SPSID 506
Query: 303 NVE----SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
VE + V ATG P + + E + + K++ ++TI
Sbjct: 507 QVEPYSSTAQVQFDEPEATG-GVPILKYKAEWR--AVGEEVWHSKWYDAKEASMEGIVTI 563
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM-AVF 417
K ++ + +A+N G + + PP + S+ +P+ +
Sbjct: 564 VGL-KPETTYAVRLAALNGKGLGEISAASEFKTQPVHSPPPPASASSSTPVPLSPPDTTW 622
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSG 463
P A+ T EP +GE + DG + +L K D G
Sbjct: 623 PLPALATTEPA-----KGEPSAPKLEGQMGEDGNSIKVNLIKQDDG 663
>S71824-1|AAB31836.1| 848|Homo sapiens N-CAM protein.
Length = 848
Score = 122 bits (293), Expect = 1e-26
Identities = 111/429 (25%), Positives = 177/429 (41%), Gaps = 28/429 (6%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C T G+ AT++V + ++ F+ P ++ +G+ V+ C P
Sbjct: 90 DAGIYKCVVTGEDGS--ESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLP- 146
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P + WK G+ ++ D R ++ L I+ ++TD G Y+C R A E ++
Sbjct: 147 PTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILA-RGEINFKDIQ 205
Query: 198 IHIK-PYLITGPEDVV---AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL- 252
+ + P I +++V A G SVT C G P P + W + K +
Sbjct: 206 VIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIF 265
Query: 253 -DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
DD S L + V DE EY C AEN G A+ +L V+ P I N +E
Sbjct: 266 SDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQV 325
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC A+G P P++ W R I + D + V+ LT+ D+
Sbjct: 326 TLTCEASGDPIPSITWRT-STRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDA-GEY 383
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
+C+A N G L V P+ + NQ C P I
Sbjct: 384 ICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQ-------VNITCEVFAYPSATI 436
Query: 430 AWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL- 483
+W+ +G+ L ++ N+ T L + ++D G Y C A +R G+ L+
Sbjct: 437 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQ 496
Query: 484 VDSPINPNI 492
D+P +P+I
Sbjct: 497 ADTPSSPSI 505
Score = 101 bits (241), Expect = 2e-20
Identities = 96/380 (25%), Positives = 147/380 (38%), Gaps = 30/380 (7%)
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLV----DGGNLVIQ 168
P + + G++ C + + ++ W NG+ L R+ +V L I
Sbjct: 26 PSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLT-PNQQRISVVWNDDSSSTLTIY 84
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
+A DAG Y+C+ G+ A +KI K P + G C V
Sbjct: 85 NANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSS 144
Query: 229 PLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAE-NSVGAVSASGY 286
P ++W+ + R VL + L++ + DEG Y CE + G ++
Sbjct: 145 LPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDI 204
Query: 287 LTVYD-PPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
+ + PP+I N VN + G C A G PEPTM W+ +G + I +K
Sbjct: 205 QVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQ--IEQEEDDEK 262
Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403
Y D + LTI DKND +C A N AG L V + P IT
Sbjct: 263 Y---IFSDDSSQLTIKKVDKNDEAE-YICIAENKAGEQDATIHLKVFA-----KPKITYV 313
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAW------YFEGEALIQNHR--RNVTNDGTLVLK 455
+ + ++ C A P P I W E + H R+ +L LK
Sbjct: 314 ENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLK 373
Query: 456 DLDKSDSGTYTCVASSRHGK 475
+ +D+G Y C AS+ G+
Sbjct: 374 SIQYTDAGEYICTASNTIGQ 393
Score = 71.3 bits (167), Expect = 2e-11
Identities = 81/303 (26%), Positives = 122/303 (40%), Gaps = 30/303 (9%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATHGRV 76
++ T Q TL C A G P P + W K G + D + I + T +V
Sbjct: 221 VNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS---SQLTIKKV 277
Query: 77 -HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+D Y C A N G ++AT+H+ V + E++ + + + V G
Sbjct: 278 DKNDEAEYICIAENKAG---EQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334
Query: 136 PEPNVYWKKNGQTL-----LFDGDS--RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
P P++ W+ + + + DG R H +L ++ + TDAG Y C A N G
Sbjct: 335 PIPSITWRTSTRNISSEEKTLDGHMVVRSH-ARVSSLTLKSIQYTDAGEYICTASNTIG- 392
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP--- 245
++S L++ P L GP V G+ V C V P + W R G +P
Sbjct: 393 QDSQSMYLEVQYAPKL-QGPVAVYTWEGNQVNITCEVFAYPSATISWFRD--GQLLPSSN 449
Query: 246 LGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+K+ + S V E G Y+C A N +G S L D PS SP+
Sbjct: 450 YSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPS---SPSID 506
Query: 303 NVE 305
VE
Sbjct: 507 QVE 509
>AB209443-1|BAD92680.1| 807|Homo sapiens Neural cell adhesion
molecule 1, 120 kDa isoform precursor variant protein.
Length = 807
Score = 122 bits (293), Expect = 1e-26
Identities = 111/429 (25%), Positives = 177/429 (41%), Gaps = 28/429 (6%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C T G+ AT++V + ++ F+ P ++ +G+ V+ C P
Sbjct: 171 DAGIYKCVVTGEDGS--ESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLP- 227
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P + WK G+ ++ D R ++ L I+ ++TD G Y+C R A E ++
Sbjct: 228 PTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILA-RGEINFKDIQ 286
Query: 198 IHIK-PYLITGPEDVV---AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL- 252
+ + P I +++V A G SVT C G P P + W + K +
Sbjct: 287 VIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIF 346
Query: 253 -DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
DD S L + V DE EY C AEN G A+ +L V+ P I N +E
Sbjct: 347 SDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQV 406
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC A+G P P++ W R I + D + V+ LT+ D+
Sbjct: 407 TLTCEASGDPIPSITWRT-STRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDA-GEY 464
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
+C+A N G L V P+ + NQ C P I
Sbjct: 465 ICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQ-------VNITCEVFAYPSATI 517
Query: 430 AWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL- 483
+W+ +G+ L ++ N+ T L + ++D G Y C A +R G+ L+
Sbjct: 518 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQ 577
Query: 484 VDSPINPNI 492
D+P +P+I
Sbjct: 578 ADTPSSPSI 586
Score = 101 bits (241), Expect = 2e-20
Identities = 96/380 (25%), Positives = 147/380 (38%), Gaps = 30/380 (7%)
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLV----DGGNLVIQ 168
P + + G++ C + + ++ W NG+ L R+ +V L I
Sbjct: 107 PSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLT-PNQQRISVVWNDDSSSTLTIY 165
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
+A DAG Y+C+ G+ A +KI K P + G C V
Sbjct: 166 NANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSS 225
Query: 229 PLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAE-NSVGAVSASGY 286
P ++W+ + R VL + L++ + DEG Y CE + G ++
Sbjct: 226 LPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDI 285
Query: 287 LTVYD-PPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
+ + PP+I N VN + G C A G PEPTM W+ +G + I +K
Sbjct: 286 QVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQ--IEQEEDDEK 343
Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403
Y D + LTI DKND +C A N AG L V + P IT
Sbjct: 344 Y---IFSDDSSQLTIKKVDKNDEAE-YICIAENKAGEQDATIHLKVFA-----KPKITYV 394
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAW------YFEGEALIQNHR--RNVTNDGTLVLK 455
+ + ++ C A P P I W E + H R+ +L LK
Sbjct: 395 ENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLK 454
Query: 456 DLDKSDSGTYTCVASSRHGK 475
+ +D+G Y C AS+ G+
Sbjct: 455 SIQYTDAGEYICTASNTIGQ 474
Score = 71.3 bits (167), Expect = 2e-11
Identities = 81/303 (26%), Positives = 122/303 (40%), Gaps = 30/303 (9%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATHGRV 76
++ T Q TL C A G P P + W K G + D + I + T +V
Sbjct: 302 VNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS---SQLTIKKV 358
Query: 77 -HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+D Y C A N G ++AT+H+ V + E++ + + + V G
Sbjct: 359 DKNDEAEYICIAENKAG---EQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 415
Query: 136 PEPNVYWKKNGQTL-----LFDGDS--RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
P P++ W+ + + + DG R H +L ++ + TDAG Y C A N G
Sbjct: 416 PIPSITWRTSTRNISSEEKTLDGHMVVRSH-ARVSSLTLKSIQYTDAGEYICTASNTIG- 473
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP--- 245
++S L++ P L GP V G+ V C V P + W R G +P
Sbjct: 474 QDSQSMYLEVQYAPKL-QGPVAVYTWEGNQVNITCEVFAYPSATISWFRD--GQLLPSSN 530
Query: 246 LGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+K+ + S V E G Y+C A N +G S L D PS SP+
Sbjct: 531 YSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPS---SPSID 587
Query: 303 NVE 305
VE
Sbjct: 588 QVE 590
>BC052946-1|AAH52946.1| 837|Homo sapiens neural cell adhesion
molecule 2 protein.
Length = 837
Score = 121 bits (291), Expect = 2e-26
Identities = 98/371 (26%), Positives = 163/371 (43%), Gaps = 30/371 (8%)
Query: 27 QPATLNCRAGGSPSPAIRW--YKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYW 84
+ A + CR SP+PA+ W + V +SD ++L L L SD G+Y
Sbjct: 130 EDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINK----SDEGIYR 185
Query: 85 CEA-TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSPEPNVYW 142
CE + G R+ + V V + +A+ G+ + C GSPEP + W
Sbjct: 186 CEGRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRAS-GSPEPAISW 244
Query: 143 KKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
+NG+ + ++ +++ G N L +++ +D G Y C A N AG E A L++ +
Sbjct: 245 FRNGKLI---EENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQ-AFLQVFV 300
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-----GNMPL-GRVKVLDD 254
+P++I + + G VT C G+P+P++ W+R+ G G+ L GR++V
Sbjct: 301 QPHIIQLKNETTYENGQ-VTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQ 359
Query: 255 ---GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
SL + +V L+D G Y CEA + +G S YL + P + GN
Sbjct: 360 HGSSSLHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIEYAPKFISNQTIYYSWEGNPIN 419
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
+C P ++ W + ++ P + T +L I T ND
Sbjct: 420 ISCDVKSNPPASIHWRRD---KLVLPAKNTTNL-KTYSTGRKMILEIAPTSDNDF-GRYN 474
Query: 372 CSAVNYAGSSF 382
C+A N+ G+ F
Sbjct: 475 CTATNHIGTRF 485
Score = 119 bits (287), Expect = 6e-26
Identities = 148/604 (24%), Positives = 239/604 (39%), Gaps = 56/604 (9%)
Query: 6 VTSGEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
V+SG+A + L V ++ + C A G P +I WY + T R ++
Sbjct: 14 VSSGQALLQVTISLSKVELSVGESKFFTCTAIGEPE-SIDWYNPQGEKIISTQRVVVQKE 72
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G+ + DAG+Y C+AT++ G + L + + FR ++ QG+
Sbjct: 73 GVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEI-YQKLTFREVVSPQEFKQGED 131
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR- 183
+ C SP P V W + + + D+R ++ NL I + ++D G Y+C R
Sbjct: 132 AEVVC-RVSSSPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGIYRCEGRV 190
Query: 184 NAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
A G + + +++ P I+ P+ + A+ G +TF CR G P P + W R+
Sbjct: 191 EARGEIDFRDIIVIVNVPP-AISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRN-- 247
Query: 241 GGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
G + K + GS L + N+I +D G Y C A N G +L V+ P I
Sbjct: 248 -GKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQ 306
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFW--SVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
N E+G V C A G P P + W +V+G T S D G +
Sbjct: 307 LKNETTYENGQVT-LVCDAEGEPIPEITWKRAVDG-FTFTEGDKSLDGRIEVKGQHGSSS 364
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L I D +DS C A + G + ++ D + P I+N + +
Sbjct: 365 LHIKDVKLSDS-GRYDCEAASRIGGH----QKSMYLDIEYAPKFISNQTIYYSWEGNPIN 419
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDS--GTYTCVAS 470
+ C P I W + L + N+ T ++L+ SD+ G Y C A+
Sbjct: 420 I-SCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTAT 478
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+ G + ADV P P ++ T+ +S+++ +
Sbjct: 479 NHIGTRFQE-------------YILALADV---PSSPYGVKIIELSQTTAKVSFNKPDSH 522
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G I YQV+V +E S W ++ QT V+ +L P TY V
Sbjct: 523 GGVPIHHYQVDV--KEVA--------SEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAV 572
Query: 591 NSHG 594
N G
Sbjct: 573 NGKG 576
>U75330-1|AAB80803.1| 837|Homo sapiens neural cell adhesion protein
protein.
Length = 837
Score = 120 bits (289), Expect = 3e-26
Identities = 148/604 (24%), Positives = 239/604 (39%), Gaps = 56/604 (9%)
Query: 6 VTSGEAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
V+SG+A + L V ++ + C A G P +I WY + T R ++ G
Sbjct: 14 VSSGQALLQVTISLSKVELSVGESKFFTCTAIGEPR-SIDWYNPQGEKIISTQRVVVQKG 72
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G+ + DAG+Y C+AT++ G + L + + FR ++ QG+
Sbjct: 73 GVRSRLTIYNANIEDAGIYRCQATDAKGQTQEATVVLEI-YQKLTFREVVSPQEFKQGED 131
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR- 183
+ C SP P V W + + + D+R+ ++ NL I + ++D G Y+C R
Sbjct: 132 AEVVC-RVSSSPAPAVSWLYHNEEVTTISDNRLAMLANNNLQILNINKSDEGIYRCEGRV 190
Query: 184 NAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
A G + + +++ P I+ P+ + A+ G +TF CR G P P + W R+
Sbjct: 191 EARGEIDFRDIIVIVNVPP-AISMPQKSFNATAERGEEMTFSCRASGSPEPAISWFRN-- 247
Query: 241 GGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
G + K + GS L + N+I +D G Y C A N G +L V+ P I
Sbjct: 248 -GKLIEENEKYILKGSNTELTVRNIINSDGGPYVCRATNKAGEDEKQAFLQVFVQPHIIQ 306
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFW--SVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
N E+G V C A G P P + W +V+G T S D G +
Sbjct: 307 LKNETTYENGQVT-LVCDAEGEPIPEITWKRAVDG-FTFTEGDKSPDGRIEVKGQHGSSS 364
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L I D K C A + G + ++ D + P I+N + +
Sbjct: 365 LHIKDV-KLSGSGRYDCEAASRIGGH----QKSMYLDIEYAPKFISNQTIYYSWEGNPIN 419
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDS--GTYTCVAS 470
+ C P I W + L + N+ T ++L+ SD+ G Y C A+
Sbjct: 420 I-SCDVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTAT 478
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+ G + ADV P P ++ T+ +S+++ +
Sbjct: 479 NHIGTRFQE-------------YILALADV---PSSPYGVKIIELSQTTAKVSFNKPDSH 522
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G I YQV+V +E S W ++ QT V+ +L P TY V
Sbjct: 523 GGVPIHHYQVDV--KEVA--------SEIWKIVRSHGVQTMVVLNNLEPNTTYEIRVAAV 572
Query: 591 NSHG 594
N G
Sbjct: 573 NGKG 576
>BX538010-1|CAD97960.1| 1183|Homo sapiens hypothetical protein
protein.
Length = 1183
Score = 120 bits (289), Expect = 3e-26
Identities = 135/497 (27%), Positives = 198/497 (39%), Gaps = 57/497 (11%)
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+K+ +G+ + LEC+ G P P +YW K L + ++ L I + D+
Sbjct: 273 NKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSEADS 329
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P + W
Sbjct: 330 GNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 388
Query: 236 RRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPP 293
+ + P + +D ++ NV Y C A N G + A+ ++ V +PP
Sbjct: 389 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 448
Query: 294 SINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA-VFD 351
I N++ V + A C G P PT+ W F G H V
Sbjct: 449 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDIYVLH 499
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L I K DS T C A N G + L + + P I P +
Sbjct: 500 ENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDPTWIVKQPEYAVVQR 553
Query: 412 KSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
SM F C T + W + L + R V D LV+ D+ DSGTYTCVA
Sbjct: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 612
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS---Q 526
++ +DS + V +P PP + D SV LSW+
Sbjct: 613 NT-----------TLDS-----VSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDD 656
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
NN + I+ Y+ + + L + T + QT +K L P + Y F
Sbjct: 657 NNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVNYSFR 704
Query: 587 VRTENSHGLSGPSPVSD 603
V NS G S PS S+
Sbjct: 705 VMAVNSIGKSLPSEASE 721
Score = 109 bits (263), Expect = 4e-23
Identities = 92/292 (31%), Positives = 132/292 (45%), Gaps = 21/292 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLF 67
APY I P ++ ++ + TL CRA G+P P I W GV + D R I G
Sbjct: 354 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI--DGDTI 411
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESK--QSAQGDT 124
R + VY C A+N YG A V VL E R L P + Q
Sbjct: 412 IFSNVQER---SSAVYQCNASNEYGYLL---ANAFVNVLAEPPRILTPANTLYQVIANRP 465
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+L+C GSP P + W K + D + L + G L I A++ G Y C+ARN
Sbjct: 466 ALLDC-AFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPVAQKDSTGTYTCVARN 523
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGG 242
G ++ + L+I +++ PE V Q GS V+F+C+V D VLW +
Sbjct: 524 KLGMAKNEV-HLEIKDPTWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD--NR 580
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
+P +D L + +V D G Y+C A ++ +VSAS L+V D P+
Sbjct: 581 ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN 632
Score = 90.2 bits (214), Expect = 4e-17
Identities = 74/289 (25%), Positives = 122/289 (42%), Gaps = 14/289 (4%)
Query: 30 TLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
+L C A G P+P I W K G+L + T L+ H +D+G Y C A
Sbjct: 283 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT----LQIIHVS-EADSGNYQCIAK 337
Query: 89 NSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N+ G T+ V V + + P++ + G+ L C G+P+P + W NG
Sbjct: 338 NALGAIHH---TISVRVKAAPYWITAPQNLVLSPGEDGTLICRA-NGNPKPRISWLTNGV 393
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
+ D +DG ++ + ++ + YQC A N G A A + + +P I
Sbjct: 394 PIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL-LANAFVNVLAEPPRILT 452
Query: 208 PEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
P + + Q ++ C G PLP + W + A G + + ++G+L +
Sbjct: 453 PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKD 512
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
G Y+C A N +G +L + DP I P V+ G++ F C
Sbjct: 513 STGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQRGSMVSFEC 561
Score = 68.1 bits (159), Expect = 2e-10
Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
+ P I +Q P D + + + C A G P P+ W + G + D ++ P G
Sbjct: 38 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 97
Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
+ + G+ + GVY C A N G A S N + + L + +LEP + QS G
Sbjct: 98 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 155
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
++VL C PP G P P ++W N L + R+ G+L + D Y C A
Sbjct: 156 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 214
Query: 183 R 183
R
Sbjct: 215 R 215
Score = 58.4 bits (135), Expect = 1e-07
Identities = 67/305 (21%), Positives = 116/305 (38%), Gaps = 30/305 (9%)
Query: 200 IKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
++P IT P+D + ++ QC G P P W R+ ++ + + G+
Sbjct: 37 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 96
Query: 258 RLDNVILAD------EGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309
L I+++ EG Y C A N GA ++ + P + ++SG
Sbjct: 97 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 156
Query: 310 ARFTC-TATGRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAV-----FDGVTVLTI 358
C G P P +FW + + + G++ D Y + + D +
Sbjct: 157 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 216
Query: 359 NDTDKNDSRNTIVCSAVNYAG-SSFVRGKLTVT------SDDDRPPPIIT--NGPSNQTL 409
N T + I ++ + + L+ T S +RPP +T SN+
Sbjct: 217 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEE 276
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
++ C A P PII W E L +N + TL + + ++DSG Y C+A
Sbjct: 277 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 336
Query: 470 SSRHG 474
+ G
Sbjct: 337 KNALG 341
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 12/218 (5%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177
+ +V++C +G P P+ W +NG D D + + G G L+I + +T G
Sbjct: 56 ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 114
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235
YQC ARN G S ++ P + E + Q+G S+ CR G P P + W
Sbjct: 115 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 174
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEAE-NSVGAVSASGYLTVYDPP 293
++ RV +G L NV+ D E Y C A N + ++V
Sbjct: 175 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISV-KVI 233
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
S++ +++ + F + R P F + EGN
Sbjct: 234 SVDELNDTIAANLSD-TEFYGAKSSRERPPTFLTPEGN 270
Score = 37.9 bits (84), Expect = 0.22
Identities = 47/192 (24%), Positives = 71/192 (36%), Gaps = 12/192 (6%)
Query: 287 LTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
L + PP+I SP ++ C A G+P P+ W+ G I +D
Sbjct: 34 LDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDI----DKDPLV 89
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
G ++ I K ++ + C+A N G++ V + V R P
Sbjct: 90 TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA-VSNNIVVR--PSRSPLWTKEKL 146
Query: 405 SNQTLPIKSMAVFPC-TAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDS 462
TL V PC I P PII W + L Q+ R + +G L ++ D+
Sbjct: 147 EPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDT 206
Query: 463 -GTYTCVASSRH 473
Y C A H
Sbjct: 207 REDYICYARFNH 218
>U63041-1|AAB04558.1| 848|Homo sapiens neural cell adhesion
molecule CD56 protein.
Length = 848
Score = 120 bits (288), Expect = 4e-26
Identities = 110/429 (25%), Positives = 177/429 (41%), Gaps = 28/429 (6%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C T G+ AT++V + ++ F+ P ++ +G+ V+ C P
Sbjct: 90 DAGIYKCVVTGEDGS--ESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLP- 146
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P + WK G+ ++ D R ++ L I+ ++TD G Y+C R A E ++
Sbjct: 147 PTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILA-RGEINFKDIQ 205
Query: 198 IHIK-PYLITGPEDVV---AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL- 252
+ + P I +++V A G SVT C P P + W + K +
Sbjct: 206 VIVNVPPTIRARQNIVNATANLGQSVTLVCDAERFPEPTMSWTKDGEQIEQEEDDEKYIF 265
Query: 253 -DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
DD S L + V DE EY C AEN G A+ +L V+ P I N +E
Sbjct: 266 SDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQV 325
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
TC A+G P P++ W R I + D + V+ LT+ D+
Sbjct: 326 TLTCEASGDPIPSITWRT-STRNISSEEKTLDGHMVVRSHARVSSLTLKSIQYTDA-GEY 383
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
+C+A N G L V P+ + NQ C P I
Sbjct: 384 ICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQ-------VNITCEVFAYPSATI 436
Query: 430 AWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHGKYVWSGALL- 483
+W+ +G+ L ++ N+ T L + ++D G Y C A +R G+ + L+
Sbjct: 437 SWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESFEFILVQ 496
Query: 484 VDSPINPNI 492
D+P +P+I
Sbjct: 497 ADTPSSPSI 505
Score = 97.9 bits (233), Expect = 2e-19
Identities = 95/380 (25%), Positives = 146/380 (38%), Gaps = 30/380 (7%)
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLV----DGGNLVIQ 168
P + + G++ C + + ++ W NG+ L R+ +V L I
Sbjct: 26 PSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLT-PNQQRISVVWNDDSSSTLTIY 84
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
+A DAG Y+C+ G+ A +KI K P + G C V
Sbjct: 85 NANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSS 144
Query: 229 PLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAE-NSVGAVSASGY 286
P ++W+ + R VL + L++ + DEG Y CE + G ++
Sbjct: 145 LPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDI 204
Query: 287 LTVYD-PPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
+ + PP+I N VN + G C A PEPTM W+ +G + I +K
Sbjct: 205 QVIVNVPPTIRARQNIVNATANLGQSVTLVCDAERFPEPTMSWTKDGEQ--IEQEEDDEK 262
Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403
Y D + LTI DKND +C A N AG L V + P IT
Sbjct: 263 Y---IFSDDSSQLTIKKVDKNDEAE-YICIAENKAGEQDATIHLKVFA-----KPKITYV 313
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAW------YFEGEALIQNHR--RNVTNDGTLVLK 455
+ + ++ C A P P I W E + H R+ +L LK
Sbjct: 314 ENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKTLDGHMVVRSHARVSSLTLK 373
Query: 456 DLDKSDSGTYTCVASSRHGK 475
+ +D+G Y C AS+ G+
Sbjct: 374 SIQYTDAGEYICTASNTIGQ 393
Score = 67.7 bits (158), Expect = 2e-10
Identities = 80/303 (26%), Positives = 121/303 (39%), Gaps = 30/303 (9%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATHGRV 76
++ T Q TL C A P P + W K G + D + I + T +V
Sbjct: 221 VNATANLGQSVTLVCDAERFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS---SQLTIKKV 277
Query: 77 -HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+D Y C A N G ++AT+H+ V + E++ + + + V G
Sbjct: 278 DKNDEAEYICIAENKAG---EQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334
Query: 136 PEPNVYWKKNGQTL-----LFDGDS--RMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
P P++ W+ + + + DG R H +L ++ + TDAG Y C A N G
Sbjct: 335 PIPSITWRTSTRNISSEEKTLDGHMVVRSH-ARVSSLTLKSIQYTDAGEYICTASNTIG- 392
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP--- 245
++S L++ P L GP V G+ V C V P + W R G +P
Sbjct: 393 QDSQSMYLEVQYAPKL-QGPVAVYTWEGNQVNITCEVFAYPSATISWFRD--GQLLPSSN 449
Query: 246 LGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+K+ + S V E G Y+C A N +G S L D PS SP+
Sbjct: 450 YSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESFEFILVQADTPS---SPSID 506
Query: 303 NVE 305
VE
Sbjct: 507 QVE 509
>DQ173642-2|ABC25979.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173641-2|ABC25974.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173640-2|ABC25969.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173639-2|ABC25964.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173638-2|ABC25959.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173637-2|ABC25954.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173636-2|ABC25949.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173635-2|ABC25944.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173634-2|ABC25939.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173633-2|ABC25934.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173632-2|ABC25929.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173631-2|ABC25924.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173630-2|ABC25919.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173629-2|ABC25914.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173628-2|ABC25909.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173627-2|ABC25904.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173626-2|ABC25899.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173625-2|ABC25894.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173624-2|ABC25889.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173623-2|ABC25884.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173622-2|ABC25879.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173621-2|ABC25874.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173620-2|ABC25869.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173619-2|ABC25864.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173618-2|ABC25859.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173617-2|ABC25854.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173616-2|ABC25849.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173615-2|ABC25844.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173614-2|ABC25839.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173613-2|ABC25834.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173612-2|ABC25829.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173611-2|ABC25824.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173610-2|ABC25819.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173609-2|ABC25814.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173608-2|ABC25809.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173607-2|ABC25804.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173606-2|ABC25799.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173605-2|ABC25794.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173604-2|ABC25789.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173603-2|ABC25784.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173602-2|ABC25779.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173601-2|ABC25774.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173600-2|ABC25769.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173599-2|ABC25764.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173598-2|ABC25759.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173597-2|ABC25755.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173596-2|ABC25750.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173595-2|ABC25745.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173594-2|ABC25740.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173593-2|ABC25735.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173592-2|ABC25730.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>DQ173589-1|ABB58724.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167726-1|AAO17629.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167725-1|AAO17628.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167724-1|AAO17627.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167723-1|AAO17626.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167722-1|AAO17625.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167721-1|AAO17624.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167720-1|AAO17623.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167719-1|AAO17622.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167718-1|AAO17621.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167717-1|AAO17620.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167716-1|AAO17619.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167715-1|AAO17618.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167714-1|AAO17617.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167713-1|AAO17616.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167712-1|AAO17615.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167711-1|AAO17614.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167710-1|AAO17613.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167709-1|AAO17612.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167708-1|AAO17611.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167707-1|AAO17610.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167706-1|AAO17609.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167705-1|AAO17608.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167704-1|AAO17607.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167703-1|AAO17606.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167702-1|AAO17605.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167701-1|AAO17604.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167700-1|AAO17603.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167699-1|AAO17602.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167698-1|AAO17601.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167697-1|AAO17600.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167696-1|AAO17599.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167695-1|AAO17598.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167694-1|AAO17597.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167693-1|AAO17596.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167692-1|AAO17595.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167691-1|AAO17594.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167690-1|AAO17593.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167689-1|AAO17592.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167688-1|AAO17591.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167687-1|AAO17590.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167686-1|AAO17589.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167685-1|AAO17588.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167684-1|AAO17587.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167683-1|AAO17586.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167682-1|AAO17585.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167681-1|AAO17584.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>AY167680-1|AAO17583.1| 534|Homo sapiens L1 cell adhesion molecule
protein.
Length = 534
Score = 119 bits (287), Expect = 6e-26
Identities = 131/491 (26%), Positives = 200/491 (40%), Gaps = 55/491 (11%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG +VLEC+ G P P + W + + D + L + + D G Y+C
Sbjct: 88 QGQPLVLECIA-EGFPTPTIKWLRPSGPM--PADRVTYQNHNKTLQLLKVGEEDDGEYRC 144
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSA 239
+A N+ G+ A + + PY + P+ + G + C+V G P P+V WR
Sbjct: 145 LAENSLGSARHAYY-VTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 203
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
+ + + G+L L NV +D CEA N G + A+ Y+ V P+ L+
Sbjct: 204 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 263
Query: 300 NSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
++ + G+ A C A G P P++ W E T++ +++ A +G L
Sbjct: 264 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL----QDERFFPYA--NGT--LG 315
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
I D ND+ C A N + + L V IT GP + S F
Sbjct: 316 IRDLQANDT-GRYFCLAANDQNNVTIMANLKVKDATQ-----ITQGPRSTIEKKGSRVTF 369
Query: 418 PCTAICTP--EPIIAWYFEGEAL--IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
C A P +P I W +G L + + + DG LV+ LD SD G Y+CVAS+
Sbjct: 370 TCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 429
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI---THNVTDTSVTLSWSQNNKI 530
LLV V S PGP + + H +T + V +SWS
Sbjct: 430 DVVESRAQLLV---------------VGS-PGPVPRLVLSDLHLLTQSQVRVSWSPAED- 472
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
++ I Y +E +E P W + + +QT +K L P + Y F V
Sbjct: 473 HNAPIEKYDIEFEDKEM-----APEK---WYSLGKVPGNQTSTTLK-LSPYVHYTFRVTA 523
Query: 590 ENSHGLSGPSP 600
N +G PSP
Sbjct: 524 INKYGPGEPSP 534
Score = 116 bits (278), Expect = 7e-25
Identities = 88/297 (29%), Positives = 133/297 (44%), Gaps = 18/297 (6%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILP 62
YVT APY + +P + A L+C+ G P P + W G+ V ++ + +
Sbjct: 158 YVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ 217
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQ 121
G L SD V CEA N +G + NA ++V L + + ++ + Q
Sbjct: 218 RGALILSNVQ----PSDTMVTQCEARNRHGLLLA-NAYIYVVQLPAKILTADNQTYMAVQ 272
Query: 122 GDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T L C G+P P+V W ++G T+L D R G L I+D + D GRY C
Sbjct: 273 GSTAYLLC-KAFGAPVPSVQWLDEDGTTVL--QDERFFPYANGTLGIRDLQANDTGRYFC 329
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRRS 238
+A N + +A LK+ + GP + + GS VTF C+ DP P + W R
Sbjct: 330 LAANDQ-NNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RG 387
Query: 239 AGGGNMPLGRVK--VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
G LG ++DG L + ++ +D+G YSC A + V + L V P
Sbjct: 388 DGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 444
Score = 107 bits (257), Expect = 2e-22
Identities = 97/346 (28%), Positives = 149/346 (43%), Gaps = 19/346 (5%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
QP L C A G P+P I+W + + +D L L+ D G Y C
Sbjct: 90 QPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGE----EDDGEYRCL 145
Query: 87 ATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
A NS G+AR +V V + L +P+S G+T L+C +G P+P V W+ N
Sbjct: 146 AENSLGSARH---AYYVTVEAAPYWLHKPQSHLYGPGETARLDC-QVQGRPQPEVTWRIN 201
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
G + + + + G L++ + + +D QC ARN G + + + ++
Sbjct: 202 GIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKIL 261
Query: 206 TGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
T +A GS+ C+ G P+P V W G + R +G+L + ++
Sbjct: 262 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQA 321
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP--EP 322
D G Y C A N V+ L V D I P S + G+ FTC A+ P +P
Sbjct: 322 NDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQP 381
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
++ W +G R + G S DKY + DG L I+ D +D N
Sbjct: 382 SITWRGDG-RDLQELGDS-DKYF---IEDG--RLVIHSLDYSDQGN 420
Score = 103 bits (246), Expect = 5e-21
Identities = 100/348 (28%), Positives = 150/348 (43%), Gaps = 31/348 (8%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA-GRYQCIARNAAGTR-----ESAI 193
+YW N + L D R+ + GNL + +D Y C A + GTR E
Sbjct: 1 IYWM-NSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA-HFPGTRTIIQKEPID 58
Query: 194 ATLK-----IHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
+K I KP L+ +VA G + +C G P P + W R +G MP
Sbjct: 59 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGP--MP 116
Query: 246 LGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
RV + +L+L V D+GEY C AENS+G+ + Y+TV P P S
Sbjct: 117 ADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLY 176
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G AR C GRP+P + W + G I +++D+ + + G +L ++ +
Sbjct: 177 GPGETARLDCQVQGRPQPEVTWRING---IPVEELAKDQKY--RIQRGALIL--SNVQPS 229
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D+ T C A N G + V P I+T S A C A
Sbjct: 230 DTMVT-QCEARNRHGLLLANAYIYVV---QLPAKILTADNQTYMAVQGSTAYLLCKAFGA 285
Query: 425 PEPIIAWYFE-GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
P P + W E G ++Q+ R +GTL ++DL +D+G Y C+A++
Sbjct: 286 PVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAAN 333
>BC039255-1|AAH39255.1| 617|Homo sapiens CNTN5 protein protein.
Length = 617
Score = 119 bits (286), Expect = 7e-26
Identities = 94/318 (29%), Positives = 136/318 (42%), Gaps = 18/318 (5%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P VT A+ + C A G+P P I W K + S A L + ++
Sbjct: 13 PFTVTAAKGTTVKMECFALGNPVPTITWMKVNGYIPSKARLRKSQA----VLEIPNVQL- 67
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C A NS G S L V + Q G + EC G P
Sbjct: 68 DDAGIYECRAENSRGK-NSFRGQLQVYTYPHWVE-KLNDTQLDSGSPLRWEC-KATGKPR 124
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P W KNG L SR+ +V+G L+I + Q+DAG YQC+A N G ++ A LK
Sbjct: 125 PTYRWLKNGVPL--SPQSRVEMVNGV-LMIHNVNQSDAGMYQCLAENKYGAIYAS-AELK 180
Query: 198 IHIK-PYLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
I P + ++ V +C+ G P P + W++ R+ +L D
Sbjct: 181 ILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENK-RIAILPD 239
Query: 255 GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
GSLR+ N +DEG+Y C EN G+ L+V +P I L+P + G C
Sbjct: 240 GSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEPTRIELTPKRTELTVGESIVLNC 299
Query: 315 TA--TGRPEPTMFWSVEG 330
A + T +W+++G
Sbjct: 300 KAIHDASLDVTFYWTLKG 317
Score = 107 bits (258), Expect = 2e-22
Identities = 92/320 (28%), Positives = 135/320 (42%), Gaps = 27/320 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P+ +E+ D + P C+A G P P RW K GV +S R + G L
Sbjct: 96 PHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGV-PLSPQSRVEMVNGVLMI--- 151
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLEC 129
H SDAG+Y C A N YG A +A L + F L K + VV+EC
Sbjct: 152 -HNVNQSDAGMYQCLAENKYG-AIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIEC 209
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
P+GSP+P + WKK + + + R+ ++ G+L I +A ++D G+Y C N G+
Sbjct: 210 -KPQGSPKPTISWKKGDRAV--RENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSA 266
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV--LWRRSA-------G 240
E IA+L + + P+ G S+ C+ D DV W
Sbjct: 267 E-IIASLSVKEPTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEE 325
Query: 241 GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
GG+ R + L + N++L G Y C + + +VS L V PP P
Sbjct: 326 GGHFESIRAQA-SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPG---PPG 381
Query: 301 SVNVESGNVARFTCTATGRP 320
V VE + T T + P
Sbjct: 382 IVIVE--EITESTATLSWSP 399
Score = 103 bits (248), Expect = 3e-21
Identities = 81/281 (28%), Positives = 121/281 (43%), Gaps = 17/281 (6%)
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
P V A G++V +C G+P+P + W + G +P L + NV L D
Sbjct: 13 PFTVTAAKGTTVKMECFALGNPVPTITWMKV--NGYIPSKARLRKSQAVLEIPNVQLDDA 70
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
G Y C AENS G S G L VY P N ++SG+ R+ C ATG+P PT W
Sbjct: 71 GIYECRAENSRGKNSFRGQLQVYTYPHWVEKLNDTQLDSGSPLRWECKATGKPRPTYRWL 130
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
G + SR + +G VL I++ +++D+ C A N G+ + +L
Sbjct: 131 KNG---VPLSPQSR-----VEMVNG--VLMIHNVNQSDA-GMYQCLAENKYGAIYASAEL 179
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEGEALIQNHRRNV 446
+ + P N + K V C +P+P I+W A+ +N R +
Sbjct: 180 KILAS---APTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAI 236
Query: 447 TNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
DG+L + + KSD G Y C + G +L V P
Sbjct: 237 LPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKEP 277
Score = 53.6 bits (123), Expect = 4e-06
Identities = 51/196 (26%), Positives = 79/196 (40%), Gaps = 19/196 (9%)
Query: 290 YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW-SVEGNRTIIFPGMSRDKYHATA 348
Y+P P +V G + C A G P PT+ W V G P +R
Sbjct: 4 YEPKIEVHFPFTVTAAKGTTVKMECFALGNPVPTITWMKVNG----YIPSKAR------- 52
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
+ VL I + +D+ C A N G + RG+L V + P ++
Sbjct: 53 LRKSQAVLEIPNVQLDDA-GIYECRAENSRGKNSFRGQLQVYT-----YPHWVEKLNDTQ 106
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
L S + C A P P W G L R + N G L++ ++++SD+G Y C+
Sbjct: 107 LDSGSPLRWECKATGKPRPTYRWLKNGVPLSPQSRVEMVN-GVLMIHNVNQSDAGMYQCL 165
Query: 469 ASSRHGKYVWSGALLV 484
A +++G S L +
Sbjct: 166 AENKYGAIYASAELKI 181
>U41725-1|AAD09360.1| 1502|Homo sapiens PTPsigma-(brain) protein.
Length = 1502
Score = 117 bits (281), Expect = 3e-25
Identities = 158/613 (25%), Positives = 238/613 (38%), Gaps = 68/613 (11%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFF 68
E P I++P D + A+ C+A G P P + W K G V S +I
Sbjct: 31 EPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 90
Query: 69 LRATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFR---LEPESKQSAQGD 123
LR R D VY C A NS G T ++ L L F + P+ K +
Sbjct: 91 LRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTR 150
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
T + C G+P+P + W K+ + + R+ + G L I+ + +TD G+Y+C+A
Sbjct: 151 TATMLCAAS-GNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVA 209
Query: 183 RNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
N+AG R S+ A L + ++ P P G +V C G P+P V W + A
Sbjct: 210 TNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGA 269
Query: 240 GG----GNMPLGRVKVLDDGSLRLDNVILADEGEY-SCEAENSVGAVSASGYLTVYDPPS 294
+MP+GR L L +V D Y C A +S+G + A +TV P
Sbjct: 270 EDLTPEDDMPVGR------NVLELTDV--KDSANYHPCVAMSSLGVIEAVAQITVKSLPK 321
Query: 295 INLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
+P + V T T +G P+P ++ +E + S+D +
Sbjct: 322 ---APGTPMVTENTATSITITWDSGNPDPVSYYVIE------YKSKSQDGPYQIKEDITT 372
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
T +I N S I SAVN G + VT ++ P + L +
Sbjct: 373 TRYSIGGLSPN-SEYEIWVSAVNSIGQG-PPSESVVTRTGEQAPARPPRNVQARMLSATT 430
Query: 414 MAVFPCTAICTPEPIIAWY-----FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
M V P +I Y E E + N +++ +D L D TYT
Sbjct: 431 MIV-QWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDE-TYTV- 487
Query: 469 ASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNN 528
V + + D P++ I + +PG P ++TS+TLSWS
Sbjct: 488 -------RVLAFTSVGDGPLSDPI---QVKTQQGVPGQPMNLRAEARSETSITLSWSPPR 537
Query: 529 KIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVR 588
+ SI+ Y E+ RE G R T YVV+ L P Y F +
Sbjct: 538 Q---ESIIKY--ELLFREGDHGREVGRTFD---------PTTSYVVEDLKPNTEYAFRLA 583
Query: 589 TENSHGLSGPSPV 601
+ GL +PV
Sbjct: 584 ARSPQGLGAFTPV 596
Score = 95.9 bits (228), Expect = 8e-19
Identities = 162/674 (24%), Positives = 251/674 (37%), Gaps = 97/674 (14%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P I P+D + +G +F C+ GDP P V W + N D+ + LR
Sbjct: 33 PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 259 LDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNVA 310
+ + DE Y C A+NSVG ++ LTV P+I++ P VE A
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
C A+G P+P + W + + P S + G L I +++ D +
Sbjct: 153 TMLCAASGNPDPEITWFKDF--LPVDPSASNGRIKQLR--SGA--LQIESSEETD-QGKY 205
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
C A N AG + P S++ +P ++ + C A+ +P P +
Sbjct: 206 ECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNI-TCVAVGSPMPYVK 264
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY-TCVASSRHGKYVWSGALLVDSPIN 489
W E L V G VL+ D DS Y CVA S G
Sbjct: 265 WMQGAEDLTPEDDMPV---GRNVLELTDVKDSANYHPCVAMSSLGV-------------- 307
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
I V SLP P P+ T TS+T++W N + Y +E S+
Sbjct: 308 --IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNP---DPVSYYVIEYKSK---- 358
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+ G I + T Y + L P Y V NS G P S+SV
Sbjct: 359 ------SQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNS---IGQGPPSESVVTR- 408
Query: 610 DSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE--ILNFYYLEGLFIY 667
TG N+ +A + + T+ + WE + + G +Y
Sbjct: 409 --------TGEQAPARPPRNV---------QARMLSATTMIVQWEEPVEPNGLIRGYRVY 451
Query: 668 FRPLDNITIEYEMKTILHSNDVSGFE-ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726
+ + K H+ D S + SL + Y ++ F +G S+ +T
Sbjct: 452 YTMEPEHPVGNWQK---HNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT 508
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
VP G P+N+ + T++ L WSPP Q II Y ++ D +
Sbjct: 509 QQGVP-GQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFREGDHGRE-----VG 558
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNG 846
T TS ++ +L Y+ ++AA + GLG F+ V R L +S P N
Sbjct: 559 RTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV------RQRTLQSIS--PKNF 610
Query: 847 EVSIVAGDFVMETW 860
+V ++ V+ +W
Sbjct: 611 KVKMIMKTSVLLSW 624
>U40317-1|AAC50567.1| 1911|Homo sapiens PTPsigma protein.
Length = 1911
Score = 117 bits (281), Expect = 3e-25
Identities = 158/613 (25%), Positives = 238/613 (38%), Gaps = 68/613 (11%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFF 68
E P I++P D + A+ C+A G P P + W K G V S +I
Sbjct: 31 EPPRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAV 90
Query: 69 LRATHGRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREEFR---LEPESKQSAQGD 123
LR R D VY C A NS G T ++ L L F + P+ K +
Sbjct: 91 LRIQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTR 150
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
T + C G+P+P + W K+ + + R+ + G L I+ + +TD G+Y+C+A
Sbjct: 151 TATMLCAAS-GNPDPEITWFKDFLPVDPSASNGRIKQLRSGALQIESSEETDQGKYECVA 209
Query: 183 RNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
N+AG R S+ A L + ++ P P G +V C G P+P V W + A
Sbjct: 210 TNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNITCVAVGSPMPYVKWMQGA 269
Query: 240 GG----GNMPLGRVKVLDDGSLRLDNVILADEGEY-SCEAENSVGAVSASGYLTVYDPPS 294
+MP+GR L L +V D Y C A +S+G + A +TV P
Sbjct: 270 EDLTPEDDMPVGR------NVLELTDV--KDSANYHPCVAMSSLGVIEAVAQITVKSLPK 321
Query: 295 INLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
+P + V T T +G P+P ++ +E + S+D +
Sbjct: 322 ---APGTPMVTENTATSITITWDSGNPDPVSYYVIE------YKSKSQDGPYQIKEDITT 372
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
T +I N S I SAVN G + VT ++ P + L +
Sbjct: 373 TRYSIGGLSPN-SEYEIWVSAVNSIGQG-PPSESVVTRTGEQAPARPPRNVQARMLSATT 430
Query: 414 MAVFPCTAICTPEPIIAWY-----FEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
M V P +I Y E E + N +++ +D L D TYT
Sbjct: 431 MIV-QWEEPVEPNGLIRGYRVYYTMEPEHPVGNWQKHNVDDSLLTTVGSLLEDE-TYTV- 487
Query: 469 ASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNN 528
V + + D P++ I + +PG P ++TS+TLSWS
Sbjct: 488 -------RVLAFTSVGDGPLSDPI---QVKTQQGVPGQPMNLRAEARSETSITLSWSPPR 537
Query: 529 KIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVR 588
+ SI+ Y E+ RE G R T YVV+ L P Y F +
Sbjct: 538 Q---ESIIKY--ELLFREGDHGREVGRTFD---------PTTSYVVEDLKPNTEYAFRLA 583
Query: 589 TENSHGLSGPSPV 601
+ GL +PV
Sbjct: 584 ARSPQGLGAFTPV 596
Score = 95.5 bits (227), Expect = 1e-18
Identities = 154/639 (24%), Positives = 237/639 (37%), Gaps = 89/639 (13%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P I P+D + +G +F C+ GDP P V W + N D+ + LR
Sbjct: 33 PRFIKEPKDQIGVSGRVASFVCQATGDPKPRVTWNKKGKKVNSQRFETIEFDESAGAVLR 92
Query: 259 LDNVILA-DEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNVA 310
+ + DE Y C A+NSVG ++ LTV P+I++ P VE A
Sbjct: 93 IQPLRTPRDENVYECVAQNSVGEITVHAKLTVLREDQLPSGFPNIDMGPQLKVVERTRTA 152
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
C A+G P+P + W + + P S + G L I +++ D +
Sbjct: 153 TMLCAASGNPDPEITWFKDF--LPVDPSASNGRIKQLR--SGA--LQIESSEETD-QGKY 205
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
C A N AG + P S++ +P ++ + C A+ +P P +
Sbjct: 206 ECVATNSAGVRYSSPANLYVRVRRVAPRFSILPMSHEIMPGGNVNI-TCVAVGSPMPYVK 264
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTY-TCVASSRHGKYVWSGALLVDSPIN 489
W E L V G VL+ D DS Y CVA S G
Sbjct: 265 WMQGAEDLTPEDDMPV---GRNVLELTDVKDSANYHPCVAMSSLGV-------------- 307
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
I V SLP P P+ T TS+T++W N + Y +E S+
Sbjct: 308 --IEAVAQITVKSLPKAPGTPMVTENTATSITITWDSGNP---DPVSYYVIEYKSK---- 358
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
+ G I + T Y + L P Y V NS G P S+SV
Sbjct: 359 ------SQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNS---IGQGPPSESVVTR- 408
Query: 610 DSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWE--ILNFYYLEGLFIY 667
TG N+ +A + + T+ + WE + + G +Y
Sbjct: 409 --------TGEQAPARPPRNV---------QARMLSATTMIVQWEEPVEPNGLIRGYRVY 451
Query: 668 FRPLDNITIEYEMKTILHSNDVSGFE-ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726
+ + K H+ D S + SL + Y ++ F +G S+ +T
Sbjct: 452 YTMEPEHPVGNWQK---HNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKT 508
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
VP G P+N+ + T++ L WSPP Q II Y ++ D +
Sbjct: 509 QQGVP-GQPMNLRAEARSETSITLSWSPPR---QESIIK-YELLFREGDHGRE-----VG 558
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
T TS ++ +L Y+ ++AA + GLG F+ V
Sbjct: 559 RTFDPTTSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVV 597
Score = 63.3 bits (147), Expect = 5e-09
Identities = 38/131 (29%), Positives = 65/131 (49%), Gaps = 1/131 (0%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
+ +L K+T+Y + + G S+ V +T +DVP PP +E LN T + + W
Sbjct: 671 LEALEKWTQYRITTVAHTEVGPGPESSPVVVRTDEDVPSAPPRKVEAEALNATAIRVLWR 730
Query: 754 PPELQLQNGIITGYNVVVNWLDVPANKSMVAI-NTTVHQATSLIMTNLTSGVSYSVQIAA 812
P Q+G I GY V ++ + +I + + A +++TNL +YS+ +AA
Sbjct: 731 SPAPGRQHGQIRGYQVHYVRMERREARGRRSIKDVMLADAQEMVITNLQPETAYSITVAA 790
Query: 813 ETIIGLGPFSQ 823
T+ G G S+
Sbjct: 791 YTMKGDGARSK 801
Score = 55.6 bits (128), Expect = 1e-06
Identities = 47/187 (25%), Positives = 79/187 (42%), Gaps = 10/187 (5%)
Query: 670 PLDNITIEYEMKT------ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRV 723
P+ IEY+ K+ I + + I L ++YE ++ +G PS S V
Sbjct: 347 PVSYYVIEYKSKSQDGPYQIKEDITTTRYSIGGLSPNSEYEIWVSAVNSIGQGPPSESVV 406
Query: 724 AQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMV 783
+T + P PP N++ +L+ TT+ ++W P NG+I GY V + P +
Sbjct: 407 TRTGEQAPARPPRNVQARMLSATTMIVQWEEP--VEPNGLIRGYRVY--YTMEPEHPVGN 462
Query: 784 AINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYP 843
V + + +L +Y+V++ A T +G GP S + G + R
Sbjct: 463 WQKHNVDDSLLTTVGSLLEDETYTVRVLAFTSVGDGPLSDPIQVKTQQGVPGQPMNLRAE 522
Query: 844 MNGEVSI 850
E SI
Sbjct: 523 ARSETSI 529
Score = 52.0 bits (119), Expect = 1e-05
Identities = 36/143 (25%), Positives = 61/143 (42%), Gaps = 5/143 (3%)
Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
+ + + L+ T+Y F L + G + +TL P PP +++ + +T +
Sbjct: 565 TSYVVEDLKPNTEYAFRLAARSPQGLGAFTPVVRQRTLQSKPSAPPQDVKCVSVRSTAIL 624
Query: 750 LKWSPPELQLQNGIITGYNVVVNWL--DVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807
+ W PP + NG + GY+V L + P K + I T T +++ L Y
Sbjct: 625 VSWRPPPPETHNGALVGYSVRYRPLGSEDPEPKEVNGIPPT---TTQILLEALEKWTQYR 681
Query: 808 VQIAAETIIGLGPFSQKVYFNID 830
+ A T +G GP S V D
Sbjct: 682 ITTVAHTEVGPGPESSPVVVRTD 704
Score = 46.4 bits (105), Expect = 6e-04
Identities = 39/136 (28%), Positives = 60/136 (44%), Gaps = 9/136 (6%)
Query: 728 DDVPDGPPINIEMF-ILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV--PANKSMVA 784
+D P G P +E + TV L+W PP +NG I Y V V PA ++ +
Sbjct: 904 EDTPRGHPQILEAAGNASAGTVLLRWLPPVPAERNGAIVKYTVAVREAGALGPARETELP 963
Query: 785 INTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPM 844
+L + L +Y +Q+ A T G GPFS V + R+ D +S P
Sbjct: 964 AGRLSRARRTLTLQGLKPDTAYDLQVRAHTRRGPGPFSPPVRY----RTFLRDQVS--PK 1017
Query: 845 NGEVSIVAGDFVMETW 860
N +V ++ V+ +W
Sbjct: 1018 NFKVKMIMKTSVLLSW 1033
>BC098401-1|AAH98401.1| 771|Homo sapiens NRCAM protein protein.
Length = 771
Score = 117 bits (281), Expect = 3e-25
Identities = 134/497 (26%), Positives = 197/497 (39%), Gaps = 57/497 (11%)
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
+K+ +G+ + LEC+ G P P +YW K L + ++ L I + D+
Sbjct: 273 NKEELRGNVLSLECIA-EGLPTPIIYWAKEDGML--PKNRTVYKNFEKTLQIIHVSEADS 329
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G YQCIA+NA G I+ +++ PY IT P+++V G T CR G+P P + W
Sbjct: 330 GNYQCIAKNALGAIHHTIS-VRVKAAPYWITAPQNLVLSPGEDGTLICRANGNPKPRISW 388
Query: 236 RRSAGGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY-DPP 293
+ + P + +D ++ NV Y C A N G + A+ ++ V +PP
Sbjct: 389 LTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYLLANAFVNVLAEPP 448
Query: 294 SINLSPNSV-NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA-VFD 351
I N++ V + A C G P PT+ W F G H V
Sbjct: 449 RILTPANTLYQVIANRPALLDCAFFGSPLPTIEW---------FKGAKGSALHEDIYVLH 499
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L I K DS T C A N G + L + + I P +
Sbjct: 500 ENGTLEIPVAQK-DSTGTYTCVARNKLGMAKNEVHLEI-----KDATWIVKQPEYAVVQR 553
Query: 412 KSMAVFPCTAIC--TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
SM F C T + W + L + R V D LV+ D+ DSGTYTCVA
Sbjct: 554 GSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDKDH-LVVADVSDDDSGTYTCVA 612
Query: 470 SSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS---Q 526
++ +DS + V +P PP + D SV LSW+
Sbjct: 613 NT-----------TLDS-----VSASAVLSVVDVPNPPFDLELTDQLDKSVQLSWTPGDD 656
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
NN + I+ Y+ + + L + T + QT +K L P + Y F
Sbjct: 657 NNSPITKFIIEYE-DAMHKPGLWHHQTEVSGT----------QTTAQLK-LSPYVNYSFR 704
Query: 587 VRTENSHGLSGPSPVSD 603
V NS G S PS S+
Sbjct: 705 VMAVNSIGKSLPSEASE 721
Score = 109 bits (263), Expect = 4e-23
Identities = 92/292 (31%), Positives = 132/292 (45%), Gaps = 21/292 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV---LVVSDTHRSILPAGGLF 67
APY I P ++ ++ + TL CRA G+P P I W GV + D R I G
Sbjct: 354 APYWITAPQNLVLSPGEDGTLICRANGNPKPRISWLTNGVPIEIAPDDPSRKI--DGDTI 411
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESK--QSAQGDT 124
R + VY C A+N YG A V VL E R L P + Q
Sbjct: 412 IFSNVQER---SSAVYQCNASNEYGYLL---ANAFVNVLAEPPRILTPANTLYQVIANRP 465
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+L+C GSP P + W K + D + L + G L I A++ G Y C+ARN
Sbjct: 466 ALLDC-AFFGSPLPTIEWFKGAKGSALHEDIYV-LHENGTLEIPVAQKDSTGTYTCVARN 523
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGG 242
G ++ + L+I +++ PE V Q GS V+F+C+V D VLW +
Sbjct: 524 KLGMAKNEV-HLEIKDATWIVKQPEYAVVQRGSMVSFECKVKHDHTLSLTVLWLKD--NR 580
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
+P +D L + +V D G Y+C A ++ +VSAS L+V D P+
Sbjct: 581 ELPSDERFTVDKDHLVVADVSDDDSGTYTCVANTTLDSVSASAVLSVVDVPN 632
Score = 87.0 bits (206), Expect = 4e-16
Identities = 73/289 (25%), Positives = 121/289 (41%), Gaps = 14/289 (4%)
Query: 30 TLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
+L C A G P+P I W K G+L + T L+ H +D+G Y C A
Sbjct: 283 SLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKT----LQIIHVS-EADSGNYQCIAK 337
Query: 89 NSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N+ G T+ V V + + P++ + G+ L C G+P+P + W NG
Sbjct: 338 NALGAIHH---TISVRVKAAPYWITAPQNLVLSPGEDGTLICRA-NGNPKPRISWLTNGV 393
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
+ D +DG ++ + ++ + YQC A N G A A + + +P I
Sbjct: 394 PIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL-LANAFVNVLAEPPRILT 452
Query: 208 PEDVVAQTGSS--VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
P + + Q ++ C G PLP + W + A G + + ++G+L +
Sbjct: 453 PANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHEDIYVLHENGTLEIPVAQKD 512
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC 314
G Y+C A N +G +L + D I P V+ G++ F C
Sbjct: 513 STGTYTCVARNKLGMAKNEVHLEIKDATWIVKQPEYAVVQRGSMVSFEC 561
Score = 68.1 bits (159), Expect = 2e-10
Identities = 52/181 (28%), Positives = 79/181 (43%), Gaps = 10/181 (5%)
Query: 10 EAPYIIEQ-PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGL 66
+ P I +Q P D + + + C A G P P+ W + G + D ++ P G
Sbjct: 38 QPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGT 97
Query: 67 FFLRA-THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGD 123
+ + G+ + GVY C A N G A S N + + L + +LEP + QS G
Sbjct: 98 LIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQS--GQ 155
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIA 182
++VL C PP G P P ++W N L + R+ G+L + D Y C A
Sbjct: 156 SLVLPCRPPIGLPPPIIFWMDNSFQRLPQSE-RVSQGLNGDLYFSNVLPEDTREDYICYA 214
Query: 183 R 183
R
Sbjct: 215 R 215
Score = 58.4 bits (135), Expect = 1e-07
Identities = 67/305 (21%), Positives = 116/305 (38%), Gaps = 30/305 (9%)
Query: 200 IKPYLIT--GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL 257
++P IT P+D + ++ QC G P P W R+ ++ + + G+
Sbjct: 37 VQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTG 96
Query: 258 RLDNVILAD------EGEYSCEAENSVGAVSASGYLT--VYDPPSINLSPNSVNVESGNV 309
L I+++ EG Y C A N GA ++ + P + ++SG
Sbjct: 97 TLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQS 156
Query: 310 ARFTC-TATGRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAV-----FDGVTVLTI 358
C G P P +FW + + + G++ D Y + + D +
Sbjct: 157 LVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARF 216
Query: 359 NDTDKNDSRNTIVCSAVNYAG-SSFVRGKLTVT------SDDDRPPPIIT--NGPSNQTL 409
N T + I ++ + + L+ T S +RPP +T SN+
Sbjct: 217 NHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERPPTFLTPEGNASNKEE 276
Query: 410 PIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
++ C A P PII W E L +N + TL + + ++DSG Y C+A
Sbjct: 277 LRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYKNFEKTLQIIHVSEADSGNYQCIA 336
Query: 470 SSRHG 474
+ G
Sbjct: 337 KNALG 341
Score = 54.4 bits (125), Expect = 2e-06
Identities = 56/218 (25%), Positives = 90/218 (41%), Gaps = 12/218 (5%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI----QDARQTDAGR 177
+ +V++C +G P P+ W +NG D D + + G G L+I + +T G
Sbjct: 56 ENIVIQC-EAKGKPPPSFSWTRNGTHFDIDKDPLVTMKPGTGTLIINIMSEGKAETYEGV 114
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLW 235
YQC ARN G S ++ P + E + Q+G S+ CR G P P + W
Sbjct: 115 YQCTARNERGAAVSNNIVVRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFW 174
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGE-YSCEAE-NSVGAVSASGYLTVYDPP 293
++ RV +G L NV+ D E Y C A N + ++V
Sbjct: 175 MDNSFQRLPQSERVSQGLNGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISV-KVI 233
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGN 331
S++ +++ + F + R P F + EGN
Sbjct: 234 SVDELNDTIAANLSD-TEFYGAKSSRERPPTFLTPEGN 270
Score = 37.9 bits (84), Expect = 0.22
Identities = 47/192 (24%), Positives = 71/192 (36%), Gaps = 12/192 (6%)
Query: 287 LTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
L + PP+I SP ++ C A G+P P+ W+ G I +D
Sbjct: 34 LDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDI----DKDPLV 89
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIV-CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
G ++ I K ++ + C+A N G++ V + V R P
Sbjct: 90 TMKPGTGTLIINIMSEGKAETYEGVYQCTARNERGAA-VSNNIVVR--PSRSPLWTKEKL 146
Query: 405 SNQTLPIKSMAVFPC-TAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDS 462
TL V PC I P PII W + L Q+ R + +G L ++ D+
Sbjct: 147 EPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNVLPEDT 206
Query: 463 -GTYTCVASSRH 473
Y C A H
Sbjct: 207 REDYICYARFNH 218
>AF531869-1|AAN04863.1| 1030|Homo sapiens transmembrane receptor
precursor PTK7-2 protein.
Length = 1030
Score = 117 bits (281), Expect = 3e-25
Identities = 87/321 (27%), Positives = 146/321 (45%), Gaps = 23/321 (7%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT------HRSILPAGGLF 67
++ P DV VAR++ A +C+ P P+++W +++ R+ + A G
Sbjct: 227 VVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSL 286
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
L R +AG+Y C G ATLH+A + + EP + + V
Sbjct: 287 LLTQVRPR---NAGIYRCIGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVT- 342
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
CLPP+G PEP+V+W+ G L G R++ G LV+ + ++DAG Y C A N AG
Sbjct: 343 -CLPPKGLPEPSVWWEHAGVRLPTHG--RVYQ-KGHELVLANIAESDAGVYTCHAANLAG 398
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
R + + + P + P+D + G C P P V+W R+ +
Sbjct: 399 QRRQDV-NITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISED-S 456
Query: 248 RVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN--LSPNSVNVE 305
R +V +G+LR+++V + D Y C + G++ A + V D S+ ++ N+ +
Sbjct: 457 RFEVFKNGTLRINSVEVYDGTWYRCMSSTPAGSIEAQARVQVLDGSSLPEWVTDNAGTLH 516
Query: 306 SGNVAR-----FTCTATGRPE 321
V R +TC A+ P+
Sbjct: 517 FARVTRDDAGNYTCIASNGPQ 537
Score = 101 bits (243), Expect = 1e-20
Identities = 126/479 (26%), Positives = 187/479 (39%), Gaps = 44/479 (9%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I+QP + + A L C +P P + W G V DT R L F A
Sbjct: 35 IKQPSSQDALQGRRALLRCEVE-APGPVHVYWLLDGA-PVQDTERRFAQGSSLSF--AAV 90
Query: 74 GRVHSDAGVYWCEATNSYG--TARSRNATLHVAVLREE--FRLEPESKQSAQGDT-VVLE 128
R+ D+G + C A + ARS NA+ ++ + P S+ Q T V L
Sbjct: 91 DRLQ-DSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAA 186
C G P P W ++G T L DG S H V NL ++ A +G Y C A +A
Sbjct: 150 CHID-GHPRPTYQWFRDG-TPLSDGQSN-HTVSSKERNLTLRPAGPEHSGLYSCCAHSAF 206
Query: 187 GTR-ESAIATLKIHIKPY--LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
G S TL I + + ++ P+DVV F C+ P P + W
Sbjct: 207 GQACSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPI 266
Query: 240 GGGNMP--LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSIN 296
+ P L R V +GSL L V + G Y C + G + L + + +
Sbjct: 267 TNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 297 LSPNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
L V +G+ R TC G PEP+++W G R P R V+
Sbjct: 327 LFEPRV-FTAGSEERVTCLPPKGLPEPSVWWEHAGVR---LPTHGR-------VYQKGHE 375
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L + + ++D+ C A N AG +TV + P P + L
Sbjct: 376 LVLANIAESDA-GVYTCHAANLAGQRRQDVNITVAT-----VPSWLKKPQDSQLEEGKPG 429
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C TP+P + WY + ++ R V +GTL + ++ D Y C++S+ G
Sbjct: 430 YLDCLTQATPKPTVVWYRNQMLISEDSRFEVFKNGTLRINSVEVYDGTWYRCMSSTPAG 488
Score = 88.6 bits (210), Expect = 1e-16
Identities = 88/328 (26%), Positives = 134/328 (40%), Gaps = 23/328 (7%)
Query: 12 PYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPAGGLFFL 69
P +++ P + + TL C G P P +W++ G L ++ ++ L
Sbjct: 128 PVVLKHPASEAEIQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTL 187
Query: 70 RATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFR---LEPESKQSAQGDTV 125
R G HS G+Y C A +++G A S+N TL +A E F L P+ A+ +
Sbjct: 188 RPA-GPEHS--GLYSCCAHSAFGQACSSQNFTLSIA--DESFARVVLAPQDVVVARYEEA 242
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-----VDGGNLVIQDARQTDAGRYQC 180
+ C P P++ W +T + + HL G+L++ R +AG Y+C
Sbjct: 243 MFHC-QFSAQPPPSLQWLFEDETPITNRSRPPHLRRATVFANGSLLLTQVRPRNAGIYRC 301
Query: 181 IARNAAGTRESAIATLKI-HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
I + G ATL + I+ + P A + VT G P P V W +
Sbjct: 302 IGQGQRGPPIILEATLHLAEIEDMPLFEPRVFTAGSEERVTC-LPPKGLPEPSVWWEHA- 359
Query: 240 GGGNMPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
G +P GRV L L N+ +D G Y+C A N G +TV PS
Sbjct: 360 -GVRLPTHGRV-YQKGHELVLANIAESDAGVYTCHAANLAGQRRQDVNITVATVPSWLKK 417
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFW 326
P +E G C P+PT+ W
Sbjct: 418 PQDSQLEEGKPGYLDCLTQATPKPTVVW 445
Score = 83.0 bits (196), Expect = 6e-15
Identities = 97/384 (25%), Positives = 151/384 (39%), Gaps = 36/384 (9%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F +P S+ + QG +L C P +VYW +G + D+ G +L
Sbjct: 34 FIKQPSSQDALQGRRALLRCEVEAPGPV-HVYWLLDGAPVQ---DTERRFAQGSSLSFAA 89
Query: 170 A-RQTDAGRYQCIARNAAGTRESAIATLKIHIK-----PYLITGP-EDVVAQTGSSVTFQ 222
R D+G +QC+AR+ E+ A +IK P ++ P + Q + VT +
Sbjct: 90 VDRLQDSGTFQCVARDDVTGEEARSANASFNIKWIEAGPVVLKHPASEAEIQPQTQVTLR 149
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVG-A 280
C + G P P W R + V + +L L G YSC A ++ G A
Sbjct: 150 CHIDGHPRPTYQWFRDGTPLSDGQSNHTVSSKERNLTLRPAGPEHSGLYSCCAHSAFGQA 209
Query: 281 VSASGY-LTVYDPP--SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
S+ + L++ D + L+P V V A F C + +P P++ W E I
Sbjct: 210 CSSQNFTLSIADESFARVVLAPQDVVVARYEEAMFHCQFSAQPPPSLQWLFEDETPITNR 269
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRP 396
AT +G +LT + + C G + L + +D P
Sbjct: 270 SRPPHLRRATVFANGSLLLT---QVRPRNAGIYRCIGQGQRGPPIILEATLHLAEIEDMP 326
Query: 397 ---PPIITNGPSNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT 451
P + T G + LP K + PEP + W G L H R
Sbjct: 327 LFEPRVFTAGSEERVTCLPPKGL----------PEPSVWWEHAGVRL-PTHGRVYQKGHE 375
Query: 452 LVLKDLDKSDSGTYTCVASSRHGK 475
LVL ++ +SD+G YTC A++ G+
Sbjct: 376 LVLANIAESDAGVYTCHAANLAGQ 399
Score = 74.9 bits (176), Expect = 2e-12
Identities = 53/143 (37%), Positives = 71/143 (49%), Gaps = 12/143 (8%)
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
AG L F R T DAG Y C A+N + L VAV F++EPE QG
Sbjct: 512 AGTLHFARVTR----DDAGNYTCIASNGPQGQIRAHVQLTVAVFIT-FKVEPERTTVYQG 566
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS---RMHLVDGGNLVIQDARQTDAGRYQ 179
T +L+C +G P+P + WK G+ + D RMH+ G+LVI D D+GRY
Sbjct: 567 HTALLQC-EAQGDPKPLIQWK--GKDRILDPTKLGPRMHIFQNGSLVIHDVAPEDSGRYT 623
Query: 180 CIARNAAGTRESAIATLKIHIKP 202
CIA N+ + + A L + KP
Sbjct: 624 CIAGNSCNIKHTE-APLYVVDKP 645
Score = 60.1 bits (139), Expect = 5e-08
Identities = 44/148 (29%), Positives = 60/148 (40%), Gaps = 4/148 (2%)
Query: 150 LFDGDSRMHLV--DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
+ DG S V + G L + DAG Y CIA N + A L + +
Sbjct: 498 VLDGSSLPEWVTDNAGTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVE 557
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLG-RVKVLDDGSLRLDNVILA 265
PE G + QC GDP P + W+ + LG R+ + +GSL + +V
Sbjct: 558 PERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPE 617
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPP 293
D G Y+C A NS L V D P
Sbjct: 618 DSGRYTCIAGNSCNIKHTEAPLYVVDKP 645
Score = 49.6 bits (113), Expect = 7e-05
Identities = 44/153 (28%), Positives = 61/153 (39%), Gaps = 11/153 (7%)
Query: 255 GSLRLDNVILADEGEYSCEAENSV-GAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
G+L V D G Y+C A N G + A LTV + + P V G+ A
Sbjct: 513 GTLHFARVTRDDAGNYTCIASNGPQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQ 572
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
C A G P+P + W +G I+ P + H +F + L I+D DS C
Sbjct: 573 CEAQGDPKPLIQW--KGKDRILDPTKLGPRMH---IFQNGS-LVIHDVAPEDS-GRYTCI 625
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406
A N L V D+P P + GP +
Sbjct: 626 AGNSCNIKHTEAPLYVV---DKPVPEESEGPGS 655
Score = 44.4 bits (100), Expect = 0.003
Identities = 27/89 (30%), Positives = 45/89 (50%), Gaps = 4/89 (4%)
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKS 460
P T+ A+ C A P+P+I W + L R ++ +G+LV+ D+
Sbjct: 558 PERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMHIFQNGSLVIHDVAPE 617
Query: 461 DSGTYTCVA-SSRHGKYVWSGALLVDSPI 488
DSG YTC+A +S + K+ + +VD P+
Sbjct: 618 DSGRYTCIAGNSCNIKHTEAPLYVVDKPV 646
Score = 38.3 bits (85), Expect = 0.17
Identities = 16/64 (25%), Positives = 30/64 (46%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D +T P +++P D + +P L+C +P P + WY+ +L+ D+ +
Sbjct: 403 DVNITVATVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYRNQMLISEDSRFEVFK 462
Query: 63 AGGL 66
G L
Sbjct: 463 NGTL 466
Score = 33.1 bits (72), Expect = 6.2
Identities = 26/78 (33%), Positives = 32/78 (41%), Gaps = 9/78 (11%)
Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT----HRSILPAGGLFFLRAT 72
+P TV + A L C A G P P I+W KG ++ T I G L
Sbjct: 557 EPERTTVYQGHTALLQCEAQGDPKPLIQW-KGKDRILDPTKLGPRMHIFQNGSL----VI 611
Query: 73 HGRVHSDAGVYWCEATNS 90
H D+G Y C A NS
Sbjct: 612 HDVAPEDSGRYTCIAGNS 629
>Y00815-1|CAA68754.1| 1897|Homo sapiens put. LAR preprotein (AA -16
to 1881) protein.
Length = 1897
Score = 116 bits (280), Expect = 4e-25
Identities = 99/336 (29%), Positives = 145/336 (43%), Gaps = 33/336 (9%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLR 70
P I+ P D T A+ C+A G P P I W K G V S I G LR
Sbjct: 23 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 82
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQG 122
RV D +Y C ATNS G N + ++VL EE + P+ K +
Sbjct: 83 IQPLRVQRDEAIYECTATNSLGEI---NTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 139
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
T + C G+P+P + W K+ + + R+ + G L I+ + ++D G+Y+C+
Sbjct: 140 RTATMLCAAG-GNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECV 198
Query: 182 ARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
A N+AGTR SA A L + ++ P P G SV C G P+P V W
Sbjct: 199 ATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMG 258
Query: 239 A----GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
A MP+GR L L NV+ + Y+C A +S+G + A+ +TV P
Sbjct: 259 AEELTKEDEMPVGR------NVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPK 310
Query: 295 INLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVE 329
P + V T T +G EP ++ ++
Sbjct: 311 ---PPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQ 343
Score = 103 bits (246), Expect = 5e-21
Identities = 155/639 (24%), Positives = 236/639 (36%), Gaps = 87/639 (13%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---L 257
KP I PED +G +F C+ G+P P + W + + V DDG+ L
Sbjct: 22 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 81
Query: 258 RLDNV-ILADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
R+ + + DE Y C A NS+G ++ S L+V + PSI++ P VE
Sbjct: 82 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKART 141
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P+P + W + + P S + + G L I ++++D +
Sbjct: 142 ATMLCAAGGNPDPEISWFKD--FLPVDPATSNGR--IKQLRSG--ALQIESSEESD-QGK 194
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG+ + + R P + PS+Q + C A+ P P +
Sbjct: 195 YECVATNSAGTRY-SAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYV 253
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
W E L + V G VL+ + S YTCVA S G
Sbjct: 254 KWMMGAEELTKEDEMPV---GRNVLELSNVVRSANYTCVAISSLGM-------------- 296
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
I V +LP PP + T TSVTL+W N S + Y ++ +
Sbjct: 297 --IEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGN---SEPVTYYGIQY----RAA 347
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
G P V T Y + L P Y F V NS G PS + T
Sbjct: 348 GTEGPFQE------VDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRART--- 398
Query: 610 DSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN--FYYLEGLFIY 667
G +S R ++A + + T+ + WE + G +Y
Sbjct: 399 -------GEQAPSSPPRR-----------VQARMLSASTMLVQWEPPEEPNGLVRGYRVY 440
Query: 668 FRPLDNITIEYEMKTILHSNDVSGF-EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726
+ P K H+ D + SL Y ++ F +G PS + +T
Sbjct: 441 YTPDSRRPPNAWHK---HNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKT 497
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
VP P + + + + T + L W P Q II Y +V W A
Sbjct: 498 QQGVP-AQPADFQAEVESDTRIQLSWLLPP---QERIIM-YELVY-W---AAEDEDQQHK 548
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
T +S + +L Y Q+AA + +G+G F+ +
Sbjct: 549 VTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTI 587
Score = 66.1 bits (154), Expect = 7e-10
Identities = 46/149 (30%), Positives = 68/149 (45%), Gaps = 7/149 (4%)
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
E TI D F +T L K T Y F L + G+ + +T +D+P G P
Sbjct: 852 EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI-RTPEDLPSGFPQ 910
Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
N+ + L T+T L W PP L +NG I Y VV + D+ + + + I T T
Sbjct: 911 NLHVTGLTTSTTELAWDPPVLAERNGRIISYTVV--FRDINSQQELQNITTD----TRFT 964
Query: 797 MTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+T L +Y +++ A T G GP S +
Sbjct: 965 LTGLKPDTTYDIKVRAWTSKGSGPLSPSI 993
Score = 59.7 bits (138), Expect = 6e-08
Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 10/148 (6%)
Query: 686 SNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745
S + S +++ L K+T+Y ++ G S+ + +T +DVP GPP +E+ LN+
Sbjct: 653 SREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNS 712
Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV----------HQATSL 795
T VH+ W P Q+G I GY V L+ + + I + +
Sbjct: 713 TAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYET 772
Query: 796 IMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
++ LT +YSV +AA T G G S+
Sbjct: 773 TISGLTPETTYSVTVAAYTTKGDGARSK 800
Score = 57.6 bits (133), Expect = 3e-07
Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 1/141 (0%)
Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
S + + L+ T Y F L G + + A+T P PP + + +TTV
Sbjct: 555 SSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVR 614
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
+ W PP +NG+IT Y+V +D ++ ++ + +S + L Y V
Sbjct: 615 VSWVPPPADSRNGVITQYSVAHEAVD-GEDRGRHVVDGISREHSSWDLVGLEKWTEYRVW 673
Query: 810 IAAETIIGLGPFSQKVYFNID 830
+ A T +G GP S V D
Sbjct: 674 VRAHTDVGPGPESSPVLVRTD 694
>BC048768-1|AAH48768.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 116 bits (280), Expect = 4e-25
Identities = 99/336 (29%), Positives = 145/336 (43%), Gaps = 33/336 (9%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLR 70
P I+ P D T A+ C+A G P P I W K G V S I G LR
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQG 122
RV D +Y C ATNS G N + ++VL EE + P+ K +
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEI---NTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 149
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
T + C G+P+P + W K+ + + R+ + G L I+ + ++D G+Y+C+
Sbjct: 150 RTATMLCAAG-GNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECV 208
Query: 182 ARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
A N+AGTR SA A L + ++ P P G SV C G P+P V W
Sbjct: 209 ATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMG 268
Query: 239 A----GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
A MP+GR L L NV+ + Y+C A +S+G + A+ +TV P
Sbjct: 269 AEELTKEDEMPVGR------NVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPK 320
Query: 295 INLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVE 329
P + V T T +G EP ++ ++
Sbjct: 321 ---PPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQ 353
Score = 103 bits (246), Expect = 5e-21
Identities = 155/639 (24%), Positives = 236/639 (36%), Gaps = 87/639 (13%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---L 257
KP I PED +G +F C+ G+P P + W + + V DDG+ L
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 258 RLDNV-ILADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
R+ + + DE Y C A NS+G ++ S L+V + PSI++ P VE
Sbjct: 92 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKART 151
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P+P + W + + P S + + G L I ++++D +
Sbjct: 152 ATMLCAAGGNPDPEISWFKD--FLPVDPATSNGR--IKQLRSG--ALQIESSEESD-QGK 204
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG+ + + R P + PS+Q + C A+ P P +
Sbjct: 205 YECVATNSAGTRY-SAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYV 263
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
W E L + V G VL+ + S YTCVA S G
Sbjct: 264 KWMMGAEELTKEDEMPV---GRNVLELSNVVRSANYTCVAISSLGM-------------- 306
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
I V +LP PP + T TSVTL+W N S + Y ++ +
Sbjct: 307 --IEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGN---SEPVTYYGIQY----RAA 357
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
G P V T Y + L P Y F V NS G PS + T
Sbjct: 358 GTEGPFQE------VDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRART--- 408
Query: 610 DSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN--FYYLEGLFIY 667
G +S R ++A + + T+ + WE + G +Y
Sbjct: 409 -------GEQAPSSPPRR-----------VQARMLSASTMLVQWEPPEEPNGLVRGYRVY 450
Query: 668 FRPLDNITIEYEMKTILHSNDVSGF-EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726
+ P K H+ D + SL Y ++ F +G PS + +T
Sbjct: 451 YTPDSRRPPNAWHK---HNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKT 507
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
VP P + + + + T + L W P Q II Y +V W A
Sbjct: 508 QQGVP-AQPADFQAEVESDTRIQLSWLLPP---QERIIM-YELVY-W---AAEDEDQQHK 558
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
T +S + +L Y Q+AA + +G+G F+ +
Sbjct: 559 VTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTI 597
Score = 69.7 bits (163), Expect = 6e-11
Identities = 43/139 (30%), Positives = 71/139 (51%), Gaps = 1/139 (0%)
Query: 686 SNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745
S + S +++ L K+T+Y ++ G S+ + +T +DVP GPP +E+ LN+
Sbjct: 663 SREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNS 722
Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAI-NTTVHQATSLIMTNLTSGV 804
T VH+ W P Q+G I GY V L+ + + I + + +A ++ LT
Sbjct: 723 TAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPET 782
Query: 805 SYSVQIAAETIIGLGPFSQ 823
+YSV +AA T G G S+
Sbjct: 783 TYSVTVAAYTTKGDGARSK 801
Score = 66.1 bits (154), Expect = 7e-10
Identities = 46/149 (30%), Positives = 68/149 (45%), Gaps = 7/149 (4%)
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
E TI D F +T L K T Y F L + G+ + +T +D+P G P
Sbjct: 853 EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI-RTPEDLPSGFPQ 911
Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
N+ + L T+T L W PP L +NG I Y VV + D+ + + + I T T
Sbjct: 912 NLHVTGLTTSTTELAWDPPVLAERNGRIISYTVV--FRDINSQQELQNITTD----TRFT 965
Query: 797 MTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+T L +Y +++ A T G GP S +
Sbjct: 966 LTGLKPDTTYDIKVRAWTSKGSGPLSPSI 994
Score = 58.4 bits (135), Expect = 1e-07
Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 1/141 (0%)
Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
S + + L+ T Y F L G + + A+T P PP + + +TTV
Sbjct: 565 SSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVR 624
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
+ W PP +NG+IT Y+V +D ++ ++ + +S + L Y V
Sbjct: 625 VSWVPPPADSRNGVITQYSVAYEAVD-GEDRGRHVVDGISREHSSWDLVGLEKWTEYRVW 683
Query: 810 IAAETIIGLGPFSQKVYFNID 830
+ A T +G GP S V D
Sbjct: 684 VRAHTDVGPGPESSPVLVRTD 704
>AL583862-10|CAI14894.1| 1907|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1907
Score = 116 bits (280), Expect = 4e-25
Identities = 99/336 (29%), Positives = 145/336 (43%), Gaps = 33/336 (9%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLR 70
P I+ P D T A+ C+A G P P I W K G V S I G LR
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQG 122
RV D +Y C ATNS G N + ++VL EE + P+ K +
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEI---NTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 149
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
T + C G+P+P + W K+ + + R+ + G L I+ + ++D G+Y+C+
Sbjct: 150 RTATMLCAAG-GNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECV 208
Query: 182 ARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
A N+AGTR SA A L + ++ P P G SV C G P+P V W
Sbjct: 209 ATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMG 268
Query: 239 A----GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
A MP+GR L L NV+ + Y+C A +S+G + A+ +TV P
Sbjct: 269 AEELTKEDEMPVGR------NVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPK 320
Query: 295 INLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVE 329
P + V T T +G EP ++ ++
Sbjct: 321 ---PPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQ 353
Score = 103 bits (246), Expect = 5e-21
Identities = 155/639 (24%), Positives = 236/639 (36%), Gaps = 87/639 (13%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---L 257
KP I PED +G +F C+ G+P P + W + + V DDG+ L
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 258 RLDNV-ILADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
R+ + + DE Y C A NS+G ++ S L+V + PSI++ P VE
Sbjct: 92 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKART 151
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P+P + W + + P S + + G L I ++++D +
Sbjct: 152 ATMLCAAGGNPDPEISWFKD--FLPVDPATSNGR--IKQLRSG--ALQIESSEESD-QGK 204
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG+ + + R P + PS+Q + C A+ P P +
Sbjct: 205 YECVATNSAGTRY-SAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYV 263
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
W E L + V G VL+ + S YTCVA S G
Sbjct: 264 KWMMGAEELTKEDEMPV---GRNVLELSNVVRSANYTCVAISSLGM-------------- 306
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
I V +LP PP + T TSVTL+W N S + Y ++ +
Sbjct: 307 --IEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGN---SEPVTYYGIQY----RAA 357
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
G P V T Y + L P Y F V NS G PS + T
Sbjct: 358 GTEGPFQE------VDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRART--- 408
Query: 610 DSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN--FYYLEGLFIY 667
G +S R ++A + + T+ + WE + G +Y
Sbjct: 409 -------GEQAPSSPPRR-----------VQARMLSASTMLVQWEPPEEPNGLVRGYRVY 450
Query: 668 FRPLDNITIEYEMKTILHSNDVSGF-EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726
+ P K H+ D + SL Y ++ F +G PS + +T
Sbjct: 451 YTPDSRRPPNAWHK---HNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKT 507
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
VP P + + + + T + L W P Q II Y +V W A
Sbjct: 508 QQGVP-AQPADFQAEVESDTRIQLSWLLPP---QERIIM-YELVY-W---AAEDEDQQHK 558
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
T +S + +L Y Q+AA + +G+G F+ +
Sbjct: 559 VTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTI 597
Score = 66.1 bits (154), Expect = 7e-10
Identities = 46/149 (30%), Positives = 68/149 (45%), Gaps = 7/149 (4%)
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
E TI D F +T L K T Y F L + G+ + +T +D+P G P
Sbjct: 862 EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI-RTPEDLPSGFPQ 920
Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
N+ + L T+T L W PP L +NG I Y VV + D+ + + + I T T
Sbjct: 921 NLHVTGLTTSTTELAWDPPVLAERNGRIISYTVV--FRDINSQQELQNITTD----TRFT 974
Query: 797 MTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+T L +Y +++ A T G GP S +
Sbjct: 975 LTGLKPDTTYDIKVRAWTSKGSGPLSPSI 1003
Score = 59.7 bits (138), Expect = 6e-08
Identities = 42/148 (28%), Positives = 69/148 (46%), Gaps = 10/148 (6%)
Query: 686 SNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745
S + S +++ L K+T+Y ++ G S+ + +T +DVP GPP +E+ LN+
Sbjct: 663 SREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNS 722
Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTV----------HQATSL 795
T VH+ W P Q+G I GY V L+ + + I + +
Sbjct: 723 TAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYET 782
Query: 796 IMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
++ LT +YSV +AA T G G S+
Sbjct: 783 TISGLTPETTYSVTVAAYTTKGDGARSK 810
Score = 58.4 bits (135), Expect = 1e-07
Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 1/141 (0%)
Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
S + + L+ T Y F L G + + A+T P PP + + +TTV
Sbjct: 565 SSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVR 624
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
+ W PP +NG+IT Y+V +D ++ ++ + +S + L Y V
Sbjct: 625 VSWVPPPADSRNGVITQYSVAYEAVD-GEDRGRHVVDGISREHSSWDLVGLEKWTEYRVW 683
Query: 810 IAAETIIGLGPFSQKVYFNID 830
+ A T +G GP S V D
Sbjct: 684 VRAHTDVGPGPESSPVLVRTD 704
>AL583862-9|CAI14895.1| 1898|Homo sapiens protein tyrosine
phosphatase, receptor type, F protein.
Length = 1898
Score = 116 bits (280), Expect = 4e-25
Identities = 99/336 (29%), Positives = 145/336 (43%), Gaps = 33/336 (9%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLR 70
P I+ P D T A+ C+A G P P I W K G V S I G LR
Sbjct: 33 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 92
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQG 122
RV D +Y C ATNS G N + ++VL EE + P+ K +
Sbjct: 93 IQPLRVQRDEAIYECTATNSLGEI---NTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 149
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
T + C G+P+P + W K+ + + R+ + G L I+ + ++D G+Y+C+
Sbjct: 150 RTATMLCAAG-GNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECV 208
Query: 182 ARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
A N+AGTR SA A L + ++ P P G SV C G P+P V W
Sbjct: 209 ATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMG 268
Query: 239 A----GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
A MP+GR L L NV+ + Y+C A +S+G + A+ +TV P
Sbjct: 269 AEELTKEDEMPVGR------NVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPK 320
Query: 295 INLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVE 329
P + V T T +G EP ++ ++
Sbjct: 321 ---PPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQ 353
Score = 103 bits (246), Expect = 5e-21
Identities = 155/639 (24%), Positives = 236/639 (36%), Gaps = 87/639 (13%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---L 257
KP I PED +G +F C+ G+P P + W + + V DDG+ L
Sbjct: 32 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 91
Query: 258 RLDNV-ILADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
R+ + + DE Y C A NS+G ++ S L+V + PSI++ P VE
Sbjct: 92 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKART 151
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P+P + W + + P S + + G L I ++++D +
Sbjct: 152 ATMLCAAGGNPDPEISWFKD--FLPVDPATSNGR--IKQLRSG--ALQIESSEESD-QGK 204
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG+ + + R P + PS+Q + C A+ P P +
Sbjct: 205 YECVATNSAGTRY-SAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYV 263
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
W E L + V G VL+ + S YTCVA S G
Sbjct: 264 KWMMGAEELTKEDEMPV---GRNVLELSNVVRSANYTCVAISSLGM-------------- 306
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
I V +LP PP + T TSVTL+W N S + Y ++ +
Sbjct: 307 --IEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGN---SEPVTYYGIQY----RAA 357
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
G P V T Y + L P Y F V NS G PS + T
Sbjct: 358 GTEGPFQE------VDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRART--- 408
Query: 610 DSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN--FYYLEGLFIY 667
G +S R ++A + + T+ + WE + G +Y
Sbjct: 409 -------GEQAPSSPPRR-----------VQARMLSASTMLVQWEPPEEPNGLVRGYRVY 450
Query: 668 FRPLDNITIEYEMKTILHSNDVSGF-EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726
+ P K H+ D + SL Y ++ F +G PS + +T
Sbjct: 451 YTPDSRRPPNAWHK---HNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKT 507
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
VP P + + + + T + L W P Q II Y +V W A
Sbjct: 508 QQGVP-AQPADFQAEVESDTRIQLSWLLPP---QERIIM-YELVY-W---AAEDEDQQHK 558
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
T +S + +L Y Q+AA + +G+G F+ +
Sbjct: 559 VTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTI 597
Score = 69.7 bits (163), Expect = 6e-11
Identities = 43/139 (30%), Positives = 71/139 (51%), Gaps = 1/139 (0%)
Query: 686 SNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745
S + S +++ L K+T+Y ++ G S+ + +T +DVP GPP +E+ LN+
Sbjct: 663 SREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNS 722
Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAI-NTTVHQATSLIMTNLTSGV 804
T VH+ W P Q+G I GY V L+ + + I + + +A ++ LT
Sbjct: 723 TAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPET 782
Query: 805 SYSVQIAAETIIGLGPFSQ 823
+YSV +AA T G G S+
Sbjct: 783 TYSVTVAAYTTKGDGARSK 801
Score = 66.1 bits (154), Expect = 7e-10
Identities = 46/149 (30%), Positives = 68/149 (45%), Gaps = 7/149 (4%)
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
E TI D F +T L K T Y F L + G+ + +T +D+P G P
Sbjct: 853 EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI-RTPEDLPSGFPQ 911
Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
N+ + L T+T L W PP L +NG I Y VV + D+ + + + I T T
Sbjct: 912 NLHVTGLTTSTTELAWDPPVLAERNGRIISYTVV--FRDINSQQELQNITTD----TRFT 965
Query: 797 MTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+T L +Y +++ A T G GP S +
Sbjct: 966 LTGLKPDTTYDIKVRAWTSKGSGPLSPSI 994
Score = 58.4 bits (135), Expect = 1e-07
Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 1/141 (0%)
Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
S + + L+ T Y F L G + + A+T P PP + + +TTV
Sbjct: 565 SSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVR 624
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
+ W PP +NG+IT Y+V +D ++ ++ + +S + L Y V
Sbjct: 625 VSWVPPPADSRNGVITQYSVAYEAVD-GEDRGRHVVDGISREHSSWDLVGLEKWTEYRVW 683
Query: 810 IAAETIIGLGPFSQKVYFNID 830
+ A T +G GP S V D
Sbjct: 684 VRAHTDVGPGPESSPVLVRTD 704
>AB177857-1|BAD66835.1| 1918|Homo sapiens LAR protein.
Length = 1918
Score = 116 bits (280), Expect = 4e-25
Identities = 99/336 (29%), Positives = 145/336 (43%), Gaps = 33/336 (9%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI-LPAGGLFFLR 70
P I+ P D T A+ C+A G P P I W K G V S I G LR
Sbjct: 53 PVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVLR 112
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQG 122
RV D +Y C ATNS G N + ++VL EE + P+ K +
Sbjct: 113 IQPLRVQRDEAIYECTATNSLGEI---NTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKA 169
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
T + C G+P+P + W K+ + + R+ + G L I+ + ++D G+Y+C+
Sbjct: 170 RTATMLCAAG-GNPDPEISWFKDFLPVDPATSNGRIKQLRSGALQIESSEESDQGKYECV 228
Query: 182 ARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
A N+AGTR SA A L + ++ P P G SV C G P+P V W
Sbjct: 229 ATNSAGTRYSAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMG 288
Query: 239 A----GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
A MP+GR L L NV+ + Y+C A +S+G + A+ +TV P
Sbjct: 289 AEELTKEDEMPVGR------NVLELSNVVRS--ANYTCVAISSLGMIEATAQVTVKALPK 340
Query: 295 INLSPNSVNVESGNVARFTCT-ATGRPEPTMFWSVE 329
P + V T T +G EP ++ ++
Sbjct: 341 ---PPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQ 373
Score = 103 bits (246), Expect = 5e-21
Identities = 155/639 (24%), Positives = 236/639 (36%), Gaps = 87/639 (13%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---L 257
KP I PED +G +F C+ G+P P + W + + V DDG+ L
Sbjct: 52 KPVFIKVPEDQTGLSGGVASFVCQATGEPKPRITWMKKGKKVSSQRFEVIEFDDGAGSVL 111
Query: 258 RLDNV-ILADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
R+ + + DE Y C A NS+G ++ S L+V + PSI++ P VE
Sbjct: 112 RIQPLRVQRDEAIYECTATNSLGEINTSAKLSVLEEEQLPPGFPSIDMGPQLKVVEKART 171
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A C A G P+P + W + + P S + + G L I ++++D +
Sbjct: 172 ATMLCAAGGNPDPEISWFKD--FLPVDPATSNGR--IKQLRSG--ALQIESSEESD-QGK 224
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AG+ + + R P + PS+Q + C A+ P P +
Sbjct: 225 YECVATNSAGTRY-SAPANLYVRVRRVAPRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYV 283
Query: 430 AWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
W E L + V G VL+ + S YTCVA S G
Sbjct: 284 KWMMGAEELTKEDEMPV---GRNVLELSNVVRSANYTCVAISSLGM-------------- 326
Query: 490 PNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLS 549
I V +LP PP + T TSVTL+W N S + Y ++ +
Sbjct: 327 --IEATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGN---SEPVTYYGIQY----RAA 377
Query: 550 GNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
G P V T Y + L P Y F V NS G PS + T
Sbjct: 378 GTEGPFQE------VDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRART--- 428
Query: 610 DSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILN--FYYLEGLFIY 667
G +S R ++A + + T+ + WE + G +Y
Sbjct: 429 -------GEQAPSSPPRR-----------VQARMLSASTMLVQWEPPEEPNGLVRGYRVY 470
Query: 668 FRPLDNITIEYEMKTILHSNDVSGF-EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQT 726
+ P K H+ D + SL Y ++ F +G PS + +T
Sbjct: 471 YTPDSRRPPNAWHK---HNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKT 527
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
VP P + + + + T + L W P Q II Y +V W A
Sbjct: 528 QQGVP-AQPADFQAEVESDTRIQLSWLLPP---QERIIM-YELVY-W---AAEDEDQQHK 578
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
T +S + +L Y Q+AA + +G+G F+ +
Sbjct: 579 VTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTI 617
Score = 69.7 bits (163), Expect = 6e-11
Identities = 43/139 (30%), Positives = 71/139 (51%), Gaps = 1/139 (0%)
Query: 686 SNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNT 745
S + S +++ L K+T+Y ++ G S+ + +T +DVP GPP +E+ LN+
Sbjct: 683 SREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNS 742
Query: 746 TTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAI-NTTVHQATSLIMTNLTSGV 804
T VH+ W P Q+G I GY V L+ + + I + + +A ++ LT
Sbjct: 743 TAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPET 802
Query: 805 SYSVQIAAETIIGLGPFSQ 823
+YSV +AA T G G S+
Sbjct: 803 TYSVTVAAYTTKGDGARSK 821
Score = 66.1 bits (154), Expect = 7e-10
Identities = 46/149 (30%), Positives = 68/149 (45%), Gaps = 7/149 (4%)
Query: 677 EYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPI 736
E TI D F +T L K T Y F L + G+ + +T +D+P G P
Sbjct: 873 EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI-RTPEDLPSGFPQ 931
Query: 737 NIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLI 796
N+ + L T+T L W PP L +NG I Y VV + D+ + + + I T T
Sbjct: 932 NLHVTGLTTSTTELAWDPPVLAERNGRIISYTVV--FRDINSQQELQNITTD----TRFT 985
Query: 797 MTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+T L +Y +++ A T G GP S +
Sbjct: 986 LTGLKPDTTYDIKVRAWTSKGSGPLSPSI 1014
Score = 58.4 bits (135), Expect = 1e-07
Identities = 37/141 (26%), Positives = 60/141 (42%), Gaps = 1/141 (0%)
Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
S + + L+ T Y F L G + + A+T P PP + + +TTV
Sbjct: 585 SSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVR 644
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
+ W PP +NG+IT Y+V +D ++ ++ + +S + L Y V
Sbjct: 645 VSWVPPPADSRNGVITQYSVAYEAVD-GEDRGRHVVDGISREHSSWDLVGLEKWTEYRVW 703
Query: 810 IAAETIIGLGPFSQKVYFNID 830
+ A T +G GP S V D
Sbjct: 704 VRAHTDVGPGPESSPVLVRTD 724
>AB040947-1|BAA96038.1| 1598|Homo sapiens KIAA1514 protein protein.
Length = 1598
Score = 116 bits (280), Expect = 4e-25
Identities = 148/615 (24%), Positives = 238/615 (38%), Gaps = 68/615 (11%)
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
V C+ G P P + W + A + L R + +DG L++ ++ D G + C A N+
Sbjct: 3 VDIPCQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNA 62
Query: 278 VGAVSASGYLTVYD-PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
G V S YL V P+I P V G C +G P P + W +G R +
Sbjct: 63 AGEVQTSTYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQ-KGERILAS 121
Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
+ ++ T + G L I+ T +D+ T C A N G L V +
Sbjct: 122 GSVQLPRF--TPLESGS--LLISPTHISDA-GTYTCLATNSRGVDEASADLVVWARTR-- 174
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGEAL-IQNHRR-NVTNDGTL 452
IT P +Q++ + A C P I W +G L ++H R + +G+L
Sbjct: 175 ---ITKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSL 231
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPIT 512
+ D GTYTC S G S L V LP P P+
Sbjct: 232 HISQTWSGDIGTYTCRVISAGGNDSRSAHL----------------RVRQLPHAPEHPVA 275
Query: 513 --HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV--H 568
V ++ L+W++ G+S ++ Y +E +S NN P W V+ V
Sbjct: 276 TLSTVERRAINLTWTKPFD-GNSPLIRYILE------MSENNAP-----WTVLLASVDPK 323
Query: 569 QTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRN 628
T VK L+P +Y F + N G S ++ V++ ++ + +++
Sbjct: 324 ATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGR---- 379
Query: 629 NILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSND 688
T+ + + P +S ++ + Y L GL + Y+ K I + D
Sbjct: 380 ---TNQSIMIQWQPPPESHQNGILKGYIIRYCLAGL----------PVGYQFKNITDA-D 425
Query: 689 VSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV 748
V+ + L +T YE + + G S+ TL VP PP N+ N+TT+
Sbjct: 426 VNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTI 485
Query: 749 HLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL-IMTNLTSGVSYS 807
W+ P Q NGI GY ++ + +MV + + ++ L Y
Sbjct: 486 RFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYF 545
Query: 808 VQIAAETIIGLGPFS 822
+ T G GP S
Sbjct: 546 TSVLCFTTPGDGPRS 560
Score = 103 bits (248), Expect = 3e-21
Identities = 63/203 (31%), Positives = 89/203 (43%), Gaps = 5/203 (2%)
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
+G P P++ W K+ + + +R + G L I D G +QC ARNAAG +++
Sbjct: 10 KGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTS 69
Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR---RSAGGGNMPLGRV 249
I P + GP D G SV C G P P + W+ R G++ L R
Sbjct: 70 TYLAVTSIAPNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRF 129
Query: 250 KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV 309
L+ GSL + ++D G Y+C A NS G AS L V+ I P +V G
Sbjct: 130 TPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQ 189
Query: 310 ARFTCTATGRPEPTM--FWSVEG 330
A C T P T+ W +G
Sbjct: 190 ASMVCGVTHDPRVTIRYIWEKDG 212
Score = 97.5 bits (232), Expect = 3e-19
Identities = 78/269 (28%), Positives = 120/269 (44%), Gaps = 16/269 (5%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
C+A G P P+I WYK +V + T GGL G V D G++ C A N+
Sbjct: 7 CQAKGVPPPSITWYKDAAVVEVEKLTRFRQRNDGGL----QISGLVPDDTGMFQCFARNA 62
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
G ++ + L V + P G +VVL C G+P P + W+K G+ +L
Sbjct: 63 AGEVQT-STYLAVTSIAPNITRGPLDSTVIDGMSVVLAC-ETSGAPRPAITWQK-GERIL 119
Query: 151 FDGD---SRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG 207
G R ++ G+L+I +DAG Y C+A N+ G E A A L + + +
Sbjct: 120 ASGSVQLPRFTPLESGSLLISPTHISDAGTYTCLATNSRGVDE-ASADLVVWARTRITKP 178
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDV--LWRR-SAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P+D G+ + C V DP + +W + A G R+++ +GSL +
Sbjct: 179 PQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWS 238
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPP 293
D G Y+C ++ G S S +L V P
Sbjct: 239 GDIGTYTCRVISAGGNDSRSAHLRVRQLP 267
Score = 75.4 bits (177), Expect = 1e-12
Identities = 66/208 (31%), Positives = 88/208 (42%), Gaps = 15/208 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDT---HRSILPAGGLF 67
AP I PLD TV L C G+P PAI W KG ++ S + R G
Sbjct: 78 APNITRGPLDSTVIDGMSVVLACETSGAPRPAITWQKGERILASGSVQLPRFTPLESGSL 137
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ TH SDAG Y C ATNS G + +A L V R P+ + +G +
Sbjct: 138 LISPTH---ISDAGTYTCLATNSRGVDEA-SADL-VVWARTRITKPPQDQSVIKGTQASM 192
Query: 128 ECLPPRGSPEPNV--YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
C P + W+K+G TL + R+ L G+L I D G Y C +A
Sbjct: 193 VC-GVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISA 251
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVA 213
G +S A L++ P+ PE VA
Sbjct: 252 GG-NDSRSAHLRVRQLPH---APEHPVA 275
Score = 74.5 bits (175), Expect = 2e-12
Identities = 84/329 (25%), Positives = 142/329 (43%), Gaps = 26/329 (7%)
Query: 504 PGPPTKPITH--NVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWV 561
P PP++P+ +V SV LSW + G S + Y ++ +RE SG W
Sbjct: 1077 PQPPSRPMVQQEDVRARSVLLSWEPGSD-GLSPVRYYTIQ--TRELPSGR--------WA 1125
Query: 562 VIARRV--HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV----GDDSNSLW 615
+ + V + + ++V L P +Y F V+ N G S S S+S+T D++ ++
Sbjct: 1126 LHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTIL 1185
Query: 616 EGTG-VSNSTEYR-NNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDN 673
T + S R D I ++ I + +L++E L + L G+
Sbjct: 1186 SVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYR--ELLYEGLRGFTLRGINNPGATWAE 1243
Query: 674 ITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDG 733
+T Y M+ + + ++ +E+ +L K+ +YE + + EG S + + VP
Sbjct: 1244 LTSMYSMRNLSRPS-LTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTA 1302
Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793
P N+ + T + + W PP L QNG I GY + W + + T
Sbjct: 1303 APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYF-W-EAQRGNLTERVKTLFLAEN 1360
Query: 794 SLIMTNLTSGVSYSVQIAAETIIGLGPFS 822
S+ + NLT +Y V +AA G GP S
Sbjct: 1361 SVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1389
Score = 66.1 bits (154), Expect = 7e-10
Identities = 46/151 (30%), Positives = 69/151 (45%), Gaps = 6/151 (3%)
Query: 683 ILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQ-TLDDVPDGPPINIEMF 741
++ N ++T L KY YE ++ F + +G PS+ + + TLDDVP GPP+ I
Sbjct: 929 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVP-GPPMGILFP 987
Query: 742 ILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLT 801
+ TT+V L W PP NGII Y + AN + V + A T L
Sbjct: 988 EVRTTSVRLIWQPP--AAPNGIILAYQITHRLNTTTANTATVEV--LAPSARQYTATGLK 1043
Query: 802 SGVSYSVQIAAETIIGLGPFSQKVYFNIDSR 832
Y +I A+T G G ++ + + R
Sbjct: 1044 PESVYLFRITAQTRKGWGEAAEALVVTTEKR 1074
Score = 54.0 bits (124), Expect = 3e-06
Identities = 43/156 (27%), Positives = 70/156 (44%), Gaps = 8/156 (5%)
Query: 661 LEGLFIYFRPLDNITIEYEMKTI-LHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719
++G IYF + +KT+ L N V ++ +L YT Y + F +G S
Sbjct: 1333 IQGYKIYFWEAQRGNLTERVKTLFLAENSV---KLKNLTGYTAYMVSVAAFNAAGDGPRS 1389
Query: 720 NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVN-WLDVPA 778
QT P P +++ L TT+V++ W P Q NGI+ GY +V V
Sbjct: 1390 TPTQGQTQQAAPSAPS-SVKFSELTTTSVNVSWEAP--QFPNGILEGYRLVYEPCSPVDG 1446
Query: 779 NKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAET 814
+V ++ + L + +L GV+Y +I A+T
Sbjct: 1447 VSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKT 1482
Score = 53.2 bits (122), Expect = 5e-06
Identities = 48/192 (25%), Positives = 93/192 (48%), Gaps = 17/192 (8%)
Query: 639 IEATPIDSKTIKLMWEILNFYYLEGL-----FIYFRPL--DNITIEYEMKTILHSNDVSG 691
+ A +S TI+ W + ++ G+ I + P + +T+ S V G
Sbjct: 475 VHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHV-G 533
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
F ++ L+K+T+Y ++ F +G S ++ +T +DVP GP ++ + T++ +
Sbjct: 534 F-VSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVP-GPVGHLSFSEILDTSLKVS 591
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT-SLIMTNLTSGVSYSVQI 810
W P +NGI+TGY ++W + N++ + + T +T LT+ +Y++++
Sbjct: 592 WQEP--GEKNGILTGYR--ISWEEY--NRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEV 645
Query: 811 AAETIIGLGPFS 822
AA T G G S
Sbjct: 646 AAMTSKGQGQVS 657
Score = 52.0 bits (119), Expect = 1e-05
Identities = 40/141 (28%), Positives = 59/141 (41%), Gaps = 5/141 (3%)
Query: 688 DVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDVPDGPPINIEMFILNTT 746
D E+ L +T Y F + PS SR QTL PD P N+ + + T
Sbjct: 729 DARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASET 788
Query: 747 TVHLKWSP-PELQLQ-NGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGV 804
++ L+W P PE++ N GY + + D + V + + +L
Sbjct: 789 SLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER--DYTIEDLEEWT 846
Query: 805 SYSVQIAAETIIGLGPFSQKV 825
Y VQ+ A IG GP+SQ V
Sbjct: 847 EYRVQVQAFNAIGSGPWSQTV 867
Score = 50.8 bits (116), Expect = 3e-05
Identities = 33/124 (26%), Positives = 56/124 (45%), Gaps = 3/124 (2%)
Query: 703 YEFFLIPFYKKFEGKPSNSRVAQTL-DDVPDGPPINIEMFILNTTTVHLKWSPPELQLQN 761
Y+F L +G+ S +L ++ P PP N+ ++ ++W PP QN
Sbjct: 338 YQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQN 397
Query: 762 GIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPF 821
GI+ GY + +P N T +L++ +L +Y +++AA GLG +
Sbjct: 398 GILKGYIIRYCLAGLPVGYQFK--NITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVY 455
Query: 822 SQKV 825
S KV
Sbjct: 456 SSKV 459
Score = 49.2 bits (112), Expect = 9e-05
Identities = 33/128 (25%), Positives = 57/128 (44%), Gaps = 2/128 (1%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
+ I L ++T+Y + F G S + V +T + VP P N+ ++++ ++
Sbjct: 837 YTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVR 896
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
WS +NG++ GY V+ D + + + S +T L V Y VQ+
Sbjct: 897 WSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEG--NSSRSAQLTGLGKYVLYEVQVL 954
Query: 812 AETIIGLG 819
A T IG G
Sbjct: 955 AFTRIGDG 962
>AL391822-3|CAI14658.1| 1174|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1174
Score = 116 bits (278), Expect = 7e-25
Identities = 87/288 (30%), Positives = 135/288 (46%), Gaps = 15/288 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 347 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 404
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 405 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 459
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 460 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 517
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 518 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 576
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+G +D SL + V D+G Y+C A + A YLTV P
Sbjct: 577 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRP 624
Score = 111 bits (266), Expect = 2e-23
Identities = 97/378 (25%), Positives = 153/378 (40%), Gaps = 23/378 (6%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
V R L C A G P+P I WYK G + SD + LR T+ D+G
Sbjct: 269 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKF---ENFNKALRITNVS-EEDSGE 324
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVY 141
Y+C A+N G+ R T+ V V + L EP++ A G+ L C G+P+P V
Sbjct: 325 YFCLASNKMGSIRH---TISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA-NGNPKPTVQ 380
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W NG+ L + V G ++ +D + + YQC N G + + +
Sbjct: 381 WMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 440
Query: 202 PYLITGPEDVVAQTGSSVT-FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
P +++ ++ + T C G P+P + W ++ G N+ G V ++GSL +
Sbjct: 441 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIK 500
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ D+G Y+C A N +G L V DP I P G + C P
Sbjct: 501 MIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDP 560
Query: 321 --EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
+ T+ W + I M ++ D +T+ + + D + + C A
Sbjct: 561 SLKLTVSWLKDDEPLYIGNRMKKED-------DSLTIFGVAERD----QGSYTCVASTEL 609
Query: 379 GSSFVRGKLTVTSDDDRP 396
+ LTV DRP
Sbjct: 610 DQDLAKAYLTVLGRPDRP 627
Score = 99.5 bits (237), Expect = 6e-20
Identities = 94/362 (25%), Positives = 153/362 (42%), Gaps = 26/362 (7%)
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
S+ +G ++LEC+ G P P++ W K G L D + L I + + D+
Sbjct: 266 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 322
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W
Sbjct: 323 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 381
Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ P +V D + D I + Y C N G + A+ +++V D P
Sbjct: 382 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 440
Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
LSP + + V N R C G P PT+ W G + + G YH V++
Sbjct: 441 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 493
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
+ L I K D + C A N G + + +L V + P I P +Q
Sbjct: 494 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 546
Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+ C P + ++W + E L +R +D +L + + + D G+YTCVA
Sbjct: 547 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 605
Query: 470 SS 471
S+
Sbjct: 606 ST 607
Score = 97.5 bits (232), Expect = 3e-19
Identities = 74/265 (27%), Positives = 120/265 (45%), Gaps = 21/265 (7%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEA 274
G + +C G P PD+ W + GG++P + K + + +LR+ NV D GEY C A
Sbjct: 272 GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLA 329
Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
N +G++ + + V P P ++ + G R C A G P+PT+ W V G
Sbjct: 330 SNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ 389
Query: 335 IFP-GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
P +R+ T +F DT + SR C+ N G ++V
Sbjct: 390 SAPPNPNREVAGDTIIF--------RDTQIS-SRAVYQCNTSNEHGYLLANAFVSVL--- 437
Query: 394 DRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG 450
D PP +++ P NQ + + + C +P P + W+ G+ + +V +G
Sbjct: 438 DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENG 495
Query: 451 TLVLKDLDKSDSGTYTCVASSRHGK 475
+L +K + K D G YTCVA++ GK
Sbjct: 496 SLEIKMIRKEDQGIYTCVATNILGK 520
Score = 66.1 bits (154), Expect = 7e-10
Identities = 48/160 (30%), Positives = 74/160 (46%), Gaps = 9/160 (5%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
D +++EC +G+P P+ +W +N + D R+ + ++ D R + G
Sbjct: 51 DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 109
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235
YQC ARN GT S L++ P + + VV Q G+ +T QC G P P + W
Sbjct: 110 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 169
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEA 274
S+ RV +G L NV+L D + +YSC A
Sbjct: 170 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 209
Score = 59.3 bits (137), Expect = 8e-08
Identities = 44/159 (27%), Positives = 67/159 (42%), Gaps = 9/159 (5%)
Query: 31 LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87
+ C A G+P+P+ W + + D S+ G + + GR G Y C A
Sbjct: 55 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 114
Query: 88 TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
N +GTA S L V+ L + L+P Q +G + L+C PP G P P ++W +
Sbjct: 115 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 172
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR 183
+ D R+ G+L + D Y C AR
Sbjct: 173 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 210
Score = 53.6 bits (123), Expect = 4e-06
Identities = 73/294 (24%), Positives = 115/294 (39%), Gaps = 30/294 (10%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD----NV 262
+D + ++ +C G+P P W R++ N+ RV + G+L +D
Sbjct: 43 KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 102
Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTAT- 317
EGEY C A N G A+S L V P NL P V V+ G C
Sbjct: 103 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 160
Query: 318 GRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAVF-DGVTVLTIND----TDKNDSR 367
G P P +FW I + G + D Y + + D T + N T +
Sbjct: 161 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 220
Query: 368 NTIVCSAVN---YAGSSFVR--GKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCT 420
N + Y SS + +R P + G ++ + ++ M + C
Sbjct: 221 NPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 280
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
A P P IAWY +G L + + + L + ++ + DSG Y C+AS++ G
Sbjct: 281 ASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 334
>AB177861-1|BAD66839.1| 836|Homo sapiens KIAA0756 splice variant 1
protein.
Length = 836
Score = 116 bits (278), Expect = 7e-25
Identities = 87/288 (30%), Positives = 135/288 (46%), Gaps = 15/288 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 144 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 201
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 202 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 256
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 257 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 314
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 315 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 373
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+G +D SL + V D+G Y+C A + A YLTV P
Sbjct: 374 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRP 421
Score = 111 bits (266), Expect = 2e-23
Identities = 97/378 (25%), Positives = 153/378 (40%), Gaps = 23/378 (6%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
V R L C A G P+P I WYK G + SD + LR T+ D+G
Sbjct: 66 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKF---ENFNKALRITNVS-EEDSGE 121
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVY 141
Y+C A+N G+ R T+ V V + L EP++ A G+ L C G+P+P V
Sbjct: 122 YFCLASNKMGSIRH---TISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA-NGNPKPTVQ 177
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W NG+ L + V G ++ +D + + YQC N G + + +
Sbjct: 178 WMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 237
Query: 202 PYLITGPEDVVAQTGSSVT-FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
P +++ ++ + T C G P+P + W ++ G N+ G V ++GSL +
Sbjct: 238 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIK 297
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ D+G Y+C A N +G L V DP I P G + C P
Sbjct: 298 MIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDP 357
Query: 321 --EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
+ T+ W + I M ++ D +T+ + + D + + C A
Sbjct: 358 SLKLTVSWLKDDEPLYIGNRMKKED-------DSLTIFGVAERD----QGSYTCVASTEL 406
Query: 379 GSSFVRGKLTVTSDDDRP 396
+ LTV DRP
Sbjct: 407 DQDLAKAYLTVLGRPDRP 424
Score = 99.5 bits (237), Expect = 6e-20
Identities = 94/362 (25%), Positives = 153/362 (42%), Gaps = 26/362 (7%)
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
S+ +G ++LEC+ G P P++ W K G L D + L I + + D+
Sbjct: 63 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 119
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W
Sbjct: 120 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 178
Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ P +V D + D I + Y C N G + A+ +++V D P
Sbjct: 179 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 237
Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
LSP + + V N R C G P PT+ W G + + G YH V++
Sbjct: 238 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 290
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
+ L I K D + C A N G + + +L V + P I P +Q
Sbjct: 291 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 343
Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+ C P + ++W + E L +R +D +L + + + D G+YTCVA
Sbjct: 344 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 402
Query: 470 SS 471
S+
Sbjct: 403 ST 404
Score = 97.5 bits (232), Expect = 3e-19
Identities = 74/265 (27%), Positives = 120/265 (45%), Gaps = 21/265 (7%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEA 274
G + +C G P PD+ W + GG++P + K + + +LR+ NV D GEY C A
Sbjct: 69 GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLA 126
Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
N +G++ + + V P P ++ + G R C A G P+PT+ W V G
Sbjct: 127 SNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ 186
Query: 335 IFP-GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
P +R+ T +F DT + SR C+ N G ++V
Sbjct: 187 SAPPNPNREVAGDTIIF--------RDTQIS-SRAVYQCNTSNEHGYLLANAFVSVL--- 234
Query: 394 DRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG 450
D PP +++ P NQ + + + C +P P + W+ G+ + +V +G
Sbjct: 235 DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENG 292
Query: 451 TLVLKDLDKSDSGTYTCVASSRHGK 475
+L +K + K D G YTCVA++ GK
Sbjct: 293 SLEIKMIRKEDQGIYTCVATNILGK 317
Score = 41.5 bits (93), Expect = 0.018
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 2/90 (2%)
Query: 387 LTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
LT +R P + G ++ + ++ M + C A P P IAWY +G L + +
Sbjct: 42 LTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAK 101
Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+ L + ++ + DSG Y C+AS++ G
Sbjct: 102 FENFNKALRITNVSEEDSGEYFCLASNKMG 131
>AB018299-1|BAA34476.3| 1222|Homo sapiens KIAA0756 protein protein.
Length = 1222
Score = 116 bits (278), Expect = 7e-25
Identities = 87/288 (30%), Positives = 135/288 (46%), Gaps = 15/288 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 400 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 457
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 458 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 512
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 513 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 570
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 571 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 629
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+G +D SL + V D+G Y+C A + A YLTV P
Sbjct: 630 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGRP 677
Score = 111 bits (266), Expect = 2e-23
Identities = 97/378 (25%), Positives = 153/378 (40%), Gaps = 23/378 (6%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
V R L C A G P+P I WYK G + SD + LR T+ D+G
Sbjct: 322 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKF---ENFNKALRITNVS-EEDSGE 377
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVY 141
Y+C A+N G+ R T+ V V + L EP++ A G+ L C G+P+P V
Sbjct: 378 YFCLASNKMGSIRH---TISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA-NGNPKPTVQ 433
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W NG+ L + V G ++ +D + + YQC N G + + +
Sbjct: 434 WMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 493
Query: 202 PYLITGPEDVVAQTGSSVT-FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
P +++ ++ + T C G P+P + W ++ G N+ G V ++GSL +
Sbjct: 494 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIK 553
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ D+G Y+C A N +G L V DP I P G + C P
Sbjct: 554 MIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDP 613
Query: 321 --EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
+ T+ W + I M ++ D +T+ + + D + + C A
Sbjct: 614 SLKLTVSWLKDDEPLYIGNRMKKED-------DSLTIFGVAERD----QGSYTCVASTEL 662
Query: 379 GSSFVRGKLTVTSDDDRP 396
+ LTV DRP
Sbjct: 663 DQDLAKAYLTVLGRPDRP 680
Score = 99.5 bits (237), Expect = 6e-20
Identities = 94/362 (25%), Positives = 153/362 (42%), Gaps = 26/362 (7%)
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
S+ +G ++LEC+ G P P++ W K G L D + L I + + D+
Sbjct: 319 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 375
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W
Sbjct: 376 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 434
Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ P +V D + D I + Y C N G + A+ +++V D P
Sbjct: 435 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 493
Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
LSP + + V N R C G P PT+ W G + + G YH V++
Sbjct: 494 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 546
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
+ L I K D + C A N G + + +L V + P I P +Q
Sbjct: 547 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 599
Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+ C P + ++W + E L +R +D +L + + + D G+YTCVA
Sbjct: 600 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 658
Query: 470 SS 471
S+
Sbjct: 659 ST 660
Score = 97.5 bits (232), Expect = 3e-19
Identities = 74/265 (27%), Positives = 120/265 (45%), Gaps = 21/265 (7%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEA 274
G + +C G P PD+ W + GG++P + K + + +LR+ NV D GEY C A
Sbjct: 325 GMDLLLECIASGVPTPDIAWYKK--GGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLA 382
Query: 275 ENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
N +G++ + + V P P ++ + G R C A G P+PT+ W V G
Sbjct: 383 SNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQ 442
Query: 335 IFP-GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
P +R+ T +F DT + SR C+ N G ++V
Sbjct: 443 SAPPNPNREVAGDTIIF--------RDTQIS-SRAVYQCNTSNEHGYLLANAFVSVL--- 490
Query: 394 DRPPPIITNGPSNQTLPI--KSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG 450
D PP +++ P NQ + + + C +P P + W+ G+ + +V +G
Sbjct: 491 DVPPRMLS--PRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENG 548
Query: 451 TLVLKDLDKSDSGTYTCVASSRHGK 475
+L +K + K D G YTCVA++ GK
Sbjct: 549 SLEIKMIRKEDQGIYTCVATNILGK 573
Score = 66.1 bits (154), Expect = 7e-10
Identities = 48/160 (30%), Positives = 74/160 (46%), Gaps = 9/160 (5%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
D +++EC +G+P P+ +W +N + D R+ + ++ D R + G
Sbjct: 104 DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 162
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235
YQC ARN GT S L++ P + + VV Q G+ +T QC G P P + W
Sbjct: 163 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 222
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEA 274
S+ RV +G L NV+L D + +YSC A
Sbjct: 223 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 262
Score = 59.3 bits (137), Expect = 8e-08
Identities = 44/159 (27%), Positives = 67/159 (42%), Gaps = 9/159 (5%)
Query: 31 LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87
+ C A G+P+P+ W + + D S+ G + + GR G Y C A
Sbjct: 108 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 167
Query: 88 TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
N +GTA S L V+ L + L+P Q +G + L+C PP G P P ++W +
Sbjct: 168 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 225
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR 183
+ D R+ G+L + D Y C AR
Sbjct: 226 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 263
Score = 53.6 bits (123), Expect = 4e-06
Identities = 73/294 (24%), Positives = 115/294 (39%), Gaps = 30/294 (10%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD----NV 262
+D + ++ +C G+P P W R++ N+ RV + G+L +D
Sbjct: 96 KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 155
Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTAT- 317
EGEY C A N G A+S L V P NL P V V+ G C
Sbjct: 156 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 213
Query: 318 GRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAVF-DGVTVLTIND----TDKNDSR 367
G P P +FW I + G + D Y + + D T + N T +
Sbjct: 214 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 273
Query: 368 NTIVCSAVN---YAGSSFVR--GKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCT 420
N + Y SS + +R P + G ++ + ++ M + C
Sbjct: 274 NPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 333
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
A P P IAWY +G L + + + L + ++ + DSG Y C+AS++ G
Sbjct: 334 ASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 387
>BC047244-1|AAH47244.1| 858|Homo sapiens neural cell adhesion
molecule 1 protein.
Length = 858
Score = 114 bits (275), Expect = 2e-24
Identities = 111/438 (25%), Positives = 176/438 (40%), Gaps = 36/438 (8%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPE 137
DAG+Y C T G+ AT++V + ++ F+ P ++ +G+ V+ C P
Sbjct: 90 DAGIYKCVVTGEDGS--ESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLP- 146
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
P + WK G+ ++ D R ++ L I+ ++TD G Y+C R A E ++
Sbjct: 147 PTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILA-RGEINFKDIQ 205
Query: 198 IHIK-PYLITGPEDVV---AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL- 252
+ + P I +++V A G SVT C G P P + W + K +
Sbjct: 206 VIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIF 265
Query: 253 -DDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA 310
DD S L + V DE EY C AEN G A+ +L V+ P I N +E
Sbjct: 266 SDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKVFAKPKITYVENQTAMELEEQV 325
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG---------VTVLTINDT 361
TC A+G P P++ W S + DG V+ LT+
Sbjct: 326 TLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSI 385
Query: 362 DKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKSMAVFPCT 420
D+ +C+A N G L V P+ + NQ C
Sbjct: 386 QYTDA-GEYICTASNTIGQDSQSMYLEVQYAPKLQGPVAVYTWEGNQ-------VNITCE 437
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLKDLDKSDSGTYTCVASSRHGK 475
P I+W+ +G+ L ++ N+ T L + ++D G Y C A +R G+
Sbjct: 438 VFAYPSATISWFRDGQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQ 497
Query: 476 YVWSGALL-VDSPINPNI 492
L+ D+P +P+I
Sbjct: 498 ESLEFILVQADTPSSPSI 515
Score = 94.3 bits (224), Expect = 2e-18
Identities = 98/390 (25%), Positives = 149/390 (38%), Gaps = 40/390 (10%)
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMHLV----DGGNLVIQ 168
P + + G++ C + + ++ W NG+ L R+ +V L I
Sbjct: 26 PSQGEISVGESKFFLCQVAGDAKDKDISWFSPNGEKLT-PNQQRISVVWNDDSSSTLTIY 84
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
+A DAG Y+C+ G+ A +KI K P + G C V
Sbjct: 85 NANIDDAGIYKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSS 144
Query: 229 PLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCEAE-NSVGAVSASGY 286
P ++W+ + R VL + L++ + DEG Y CE + G ++
Sbjct: 145 LPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEGTYRCEGRILARGEINFKDI 204
Query: 287 LTVYD-PPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDK 343
+ + PP+I N VN + G C A G PEPTM W+ +G + I +K
Sbjct: 205 QVIVNVPPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQ--IEQEEDDEK 262
Query: 344 YHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG 403
Y D + LTI DKND +C A N AG L V + P IT
Sbjct: 263 Y---IFSDDSSQLTIKKVDKNDEAE-YICIAENKAGEQDATIHLKVFA-----KPKITYV 313
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAW-------YFEGEALIQNHRRNVTNDG------ 450
+ + ++ C A P P I W E +A + T DG
Sbjct: 314 ENQTAMELEEQVTLTCEASGDPIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRS 373
Query: 451 -----TLVLKDLDKSDSGTYTCVASSRHGK 475
+L LK + +D+G Y C AS+ G+
Sbjct: 374 HARVSSLTLKSIQYTDAGEYICTASNTIGQ 403
Score = 66.1 bits (154), Expect = 7e-10
Identities = 79/312 (25%), Positives = 124/312 (39%), Gaps = 38/312 (12%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGLFFLRATHGRV 76
++ T Q TL C A G P P + W K G + D + I + T +V
Sbjct: 221 VNATANLGQSVTLVCDAEGFPEPTMSWTKDGEQIEQEEDDEKYIFSDDS---SQLTIKKV 277
Query: 77 -HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+D Y C A N G ++AT+H+ V + E++ + + + V G
Sbjct: 278 DKNDEAEYICIAENKAG---EQDATIHLKVFAKPKITYVENQTAMELEEQVTLTCEASGD 334
Query: 136 PEPNVYWKKNGQTLLFDGDS------RMHLVDG----------GNLVIQDARQTDAGRYQ 179
P P++ W+ + + + + + + +DG +L ++ + TDAG Y
Sbjct: 335 PIPSITWRTSTRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAGEYI 394
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
C A N G ++S L++ P L GP V G+ V C V P + W R
Sbjct: 395 CTASNTIG-QDSQSMYLEVQYAPKL-QGPVAVYTWEGNQVNITCEVFAYPSATISWFRD- 451
Query: 240 GGGNMP---LGRVKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPP 293
G +P +K+ + S V E G Y+C A N +G S L D P
Sbjct: 452 -GQLLPSSNYSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTP 510
Query: 294 SINLSPNSVNVE 305
S SP+ VE
Sbjct: 511 S---SPSIDQVE 519
>BC008124-1|AAH08124.2| 294|Homo sapiens NFASC protein protein.
Length = 294
Score = 114 bits (275), Expect = 2e-24
Identities = 86/284 (30%), Positives = 134/284 (47%), Gaps = 15/284 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 11 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 68
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 69 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 123
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 124 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 181
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 182 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 240
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+G +D SL + V D+G Y+C A + A YLTV
Sbjct: 241 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 284
Score = 80.2 bits (189), Expect = 4e-14
Identities = 56/223 (25%), Positives = 92/223 (41%), Gaps = 3/223 (1%)
Query: 100 TLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH 158
T+ V V + L EP++ A G+ L C G+P+P V W NG+ L +
Sbjct: 3 TISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA-NGNPKPTVQWMVNGEPLQSAPPNPNR 61
Query: 159 LVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
V G ++ +D + + YQC N G + + + P +++ ++ +
Sbjct: 62 EVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN 121
Query: 219 VT-FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
T C G P+P + W ++ G N+ G V ++GSL + + D+G Y+C A N
Sbjct: 122 RTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNI 181
Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+G L V DP I P G + C P
Sbjct: 182 LGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDP 224
Score = 73.3 bits (172), Expect = 5e-12
Identities = 73/285 (25%), Positives = 118/285 (41%), Gaps = 24/285 (8%)
Query: 195 TLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVK 250
T+ + +K PY + P++++ G CR G+P P V W + P +
Sbjct: 3 TISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNRE 62
Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS--VNVESGN 308
V D + D I + Y C N G + A+ +++V D P LSP + + V N
Sbjct: 63 VAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRVILYN 121
Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
R C G P PT+ W G + + G YH V++ + L I K D +
Sbjct: 122 RTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYENGS-LEIKMIRKED-QG 172
Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP--E 426
C A N G + + +L V + P I P +Q + C P +
Sbjct: 173 IYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLK 227
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
++W + E L +R +D +L + + + D G+YTCVAS+
Sbjct: 228 LTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVAST 271
Score = 58.8 bits (136), Expect = 1e-07
Identities = 49/181 (27%), Positives = 80/181 (44%), Gaps = 18/181 (9%)
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGN-RTIIFPGMSRDKYHATAVFDGVTVLT 357
P ++ + G R C A G P+PT+ W V G P +R+ T +F
Sbjct: 18 PKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIF------- 70
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMA 415
DT + SR C+ N G ++V D PP +++ P NQ + + +
Sbjct: 71 -RDT-QISSRAVYQCNTSNEHGYLLANAFVSVL---DVPPRMLS--PRNQLIRVILYNRT 123
Query: 416 VFPCTAICTPEPIIAWYFEGE-ALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C +P P + W+ G+ + + +V +G+L +K + K D G YTCVA++ G
Sbjct: 124 RLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKEDQGIYTCVATNILG 183
Query: 475 K 475
K
Sbjct: 184 K 184
>AL391822-7|CAI14662.1| 1165|Homo sapiens neurofascin homolog
(chicken) protein.
Length = 1165
Score = 114 bits (275), Expect = 2e-24
Identities = 86/284 (30%), Positives = 134/284 (47%), Gaps = 15/284 (5%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS---DTHRSILPAGGLF 67
APY +++P ++ +A + L CRA G+P P ++W G + S + +R + AG
Sbjct: 323 APYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGEPLQSAPPNPNREV--AGDTI 380
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTV 125
R T S VY C +N +G + NA + V + L P ++ + +
Sbjct: 381 IFRDTQ---ISSRAVYQCNTSNEHGYLLA-NAFVSVLDVPPRM-LSPRNQLIRVILYNRT 435
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L+C P GSP P + W KNGQ DG H+ + G+L I+ R+ D G Y C+A N
Sbjct: 436 RLDC-PFFGSPIPTLRWFKNGQGSNLDG-GNYHVYENGSLEIKMIRKEDQGIYTCVATNI 493
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
G E+ + L++ + PED VA+ G++V +CRV DP + +
Sbjct: 494 LGKAENQV-RLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKDDEPLY 552
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+G +D SL + V D+G Y+C A + A YLTV
Sbjct: 553 IGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTV 596
Score = 109 bits (262), Expect = 6e-23
Identities = 96/378 (25%), Positives = 153/378 (40%), Gaps = 23/378 (6%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
V R L C A G P+P I WYK G + SD + LR T+ D+G
Sbjct: 245 VLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKF---ENFNKALRITNVS-EEDSGE 300
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRL-EPESKQSAQGDTVVLECLPPRGSPEPNVY 141
Y+C A+N G+ R T+ V V + L EP++ A G+ L C G+P+P V
Sbjct: 301 YFCLASNKMGSIRH---TISVRVKAAPYWLDEPKNLILAPGEDGRLVCRA-NGNPKPTVQ 356
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W NG+ L + V G ++ +D + + YQC N G + + +
Sbjct: 357 WMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVP 416
Query: 202 PYLITGPEDVVAQTGSSVT-FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLD 260
P +++ ++ + T C G P+P + W ++ G N+ G V ++GSL +
Sbjct: 417 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIK 476
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ D+G Y+C A N +G L V DP I P G + C P
Sbjct: 477 MIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDP 536
Query: 321 --EPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
+ T+ W + I M ++ D +T+ + + D + + C A
Sbjct: 537 SLKLTVSWLKDDEPLYIGNRMKKED-------DSLTIFGVAERD----QGSYTCVASTEL 585
Query: 379 GSSFVRGKLTVTSDDDRP 396
+ LTV +D P
Sbjct: 586 DQDLAKAYLTVLADQATP 603
Score = 103 bits (247), Expect = 4e-21
Identities = 127/500 (25%), Positives = 203/500 (40%), Gaps = 48/500 (9%)
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDA 175
S+ +G ++LEC+ G P P++ W K G L D + L I + + D+
Sbjct: 242 SQMVLRGMDLLLECIAS-GVPTPDIAWYKKGGDLPSDKAKFENFNKA--LRITNVSEEDS 298
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
G Y C+A N G+ I+ +++ PY + P++++ G CR G+P P V W
Sbjct: 299 GEYFCLASNKMGSIRHTIS-VRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQW 357
Query: 236 RRSAGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ P +V D + D I + Y C N G + A+ +++V D P
Sbjct: 358 MVNGEPLQSAPPNPNREVAGDTIIFRDTQI-SSRAVYQCNTSNEHGYLLANAFVSVLDVP 416
Query: 294 SINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
LSP + + V N R C G P PT+ W G + + G YH V++
Sbjct: 417 PRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGG----NYH---VYE 469
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
+ L I K D + C A N G + + +L V + P I P +Q
Sbjct: 470 NGS-LEIKMIRKED-QGIYTCVATNILGKAENQVRLEV-----KDPTRIYRMPEDQVARR 522
Query: 412 KSMAVFPCTAICTP--EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
+ C P + ++W + E L +R +D +L + + + D G+YTCVA
Sbjct: 523 GTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDD-SLTIFGVAERDQGSYTCVA 581
Query: 470 SSRHGKYVWSGAL--LVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVTD---TSVTLS 523
S+ + + L L D N +++LP G P +P +TD SV L+
Sbjct: 582 STELDQDLAKAYLTVLADQATPTN-------RLAALPKGRPDRPRDLELTDLAERSVRLT 634
Query: 524 WSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITY 583
W + +S I Y V+ + G W ++ + V L P + Y
Sbjct: 635 WIPGD-ANNSPITDYVVQFEEDQFQPG--------VWHDHSKYPGSVNSAVLRLSPYVNY 685
Query: 584 MFIVRTENSHGLSGPSPVSD 603
F V N G S PS S+
Sbjct: 686 QFRVIAINEVGSSHPSLPSE 705
Score = 66.1 bits (154), Expect = 7e-10
Identities = 48/160 (30%), Positives = 74/160 (46%), Gaps = 9/160 (5%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-----QTDAGR 177
D +++EC +G+P P+ +W +N + D R+ + ++ D R + G
Sbjct: 27 DNILIEC-EAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGE 85
Query: 178 YQCIARNAAGTRESAIATLKIHIKP-YLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW 235
YQC ARN GT S L++ P + + VV Q G+ +T QC G P P + W
Sbjct: 86 YQCFARNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFW 145
Query: 236 RRSAGGGNMPLGRVKVLDDGSLRLDNVILAD-EGEYSCEA 274
S+ RV +G L NV+L D + +YSC A
Sbjct: 146 MSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNA 185
Score = 59.3 bits (137), Expect = 8e-08
Identities = 44/159 (27%), Positives = 67/159 (42%), Gaps = 9/159 (5%)
Query: 31 LNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFLR-ATHGRVHSDAGVYWCEA 87
+ C A G+P+P+ W + + D S+ G + + GR G Y C A
Sbjct: 31 IECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGRPEEYEGEYQCFA 90
Query: 88 TNSYGTARSRNATLHVAV--LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
N +GTA S L V+ L + L+P Q +G + L+C PP G P P ++W +
Sbjct: 91 RNKFGTALSNRIRLQVSKSPLWPKENLDPVVVQ--EGAPLTLQCNPPPGLPSPVIFWMSS 148
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR-YQCIAR 183
+ D R+ G+L + D Y C AR
Sbjct: 149 SMEPITQ-DKRVSQGHNGDLYFSNVMLQDMQTDYSCNAR 186
Score = 53.6 bits (123), Expect = 4e-06
Identities = 73/294 (24%), Positives = 115/294 (39%), Gaps = 30/294 (10%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD-DGSLRLD----NV 262
+D + ++ +C G+P P W R++ N+ RV + G+L +D
Sbjct: 19 KDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLVIDFRSGGR 78
Query: 263 ILADEGEYSCEAENSVG-AVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTAT- 317
EGEY C A N G A+S L V P NL P V V+ G C
Sbjct: 79 PEEYEGEYQCFARNKFGTALSNRIRLQVSKSPLWPKENLDP--VVVQEGAPLTLQCNPPP 136
Query: 318 GRPEPTMFWSVEGNRTI-----IFPGMSRDKYHATAVF-DGVTVLTIND----TDKNDSR 367
G P P +FW I + G + D Y + + D T + N T +
Sbjct: 137 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 196
Query: 368 NTIVCSAVN---YAGSSFVR--GKLTVTSDDDRPPPII-TNGPSNQTLPIKSM-AVFPCT 420
N + Y SS + +R P + G ++ + ++ M + C
Sbjct: 197 NPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 256
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
A P P IAWY +G L + + + L + ++ + DSG Y C+AS++ G
Sbjct: 257 ASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMG 310
>AK128160-1|BAC87305.1| 632|Homo sapiens protein ( Homo sapiens
cDNA FLJ46283 fis, clone TESTI4031173. ).
Length = 632
Score = 112 bits (270), Expect = 6e-24
Identities = 99/345 (28%), Positives = 145/345 (42%), Gaps = 27/345 (7%)
Query: 10 EAPYIIE-QPLDVTVARHQPATLNCRAGGSPSPAIRWYK--GGVLVVSDTHRS---ILPA 63
E P I+ + T+ + A L C A G+P P I W + G+ + S +LP
Sbjct: 273 EKPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPN 332
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--Q 121
G L R D G Y C A+N +GT + TL V LE +K+
Sbjct: 333 GTLSIQRVE----IQDRGQYLCSASNLFGTDH-LHVTLSVVSYPPRI-LERRTKEITVHS 386
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD--SRMHLVD-GGNLVIQDARQTDAGRY 178
G TV L+C G P P V W QT++ + SR +V G LV+ + D G Y
Sbjct: 387 GSTVELKC-RAEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFY 445
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQT-GSSVTFQCRVGGDPLPDVLWRR 237
+C+A N G + I P ++ V+ T G S+ C G P P V W
Sbjct: 446 KCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWVL 505
Query: 238 SAGGGNMPL----GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-- 291
S G PL ++ + +G+L + N+ +D G Y C A +S G+ LT+ +
Sbjct: 506 SDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTGSERRVVMLTMEERV 565
Query: 292 -PPSIN-LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
P I S V G+ C+ATG P+P + W + +
Sbjct: 566 TSPRIEAASQKRTEVNFGDKLLLNCSATGEPKPQIMWRLPSKAVV 610
Score = 109 bits (261), Expect = 8e-23
Identities = 83/287 (28%), Positives = 128/287 (44%), Gaps = 22/287 (7%)
Query: 201 KPYLITGPEDVVAQTGSSVTF-QCRVGGDPLPDVLWRRSAGGGNMPL----GRVKVLDDG 255
KP ++ G +S F C G+PLP + W R G ++ RV+VL +G
Sbjct: 274 KPRIVGGKAASFTIPANSDAFLPCEAVGNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNG 333
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSPNSVNVESGNVARFT 313
+L + V + D G+Y C A N G L+V Y P + + V SG+
Sbjct: 334 TLSIQRVEIQDRGQYLCSASNLFGTDHLHVTLSVVSYPPRILERRTKEITVHSGSTVELK 393
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
C A GRP PT+ W + N+T++ S+ A DG VL ++ D R C
Sbjct: 394 CRAEGRPSPTVTW-ILANQTVVSES-SQGSRQAVVTVDGTLVL--HNLSIYD-RGFYKCV 448
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWY 432
A N G + K+ V + PP+I + ++ PCTA TP+P + W
Sbjct: 449 ASNPGGQDSLLVKIQVIA----APPVILEQRRQVIVGTWGESLKLPCTAKGTPQPSVYWV 504
Query: 433 FEGEALIQ-----NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
++ N + + ++GTL +++L SD GTY C+A+S G
Sbjct: 505 LSDGTEVKPLQFTNSKLFLFSNGTLYIRNLASSDRGTYECIATSSTG 551
Score = 97.1 bits (231), Expect = 3e-19
Identities = 84/332 (25%), Positives = 138/332 (41%), Gaps = 19/332 (5%)
Query: 134 GSPEPNVYWKKNGQTLLFDG---DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G+P P ++W + L +SR+ ++ G L IQ D G+Y C A N GT
Sbjct: 301 GNPLPTIHWTRVPSGLDLSKRKQNSRVQVLPNGTLSIQRVEIQDRGQYLCSASNLFGTDH 360
Query: 191 SAIATLKIHIKPYLI-TGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMP 245
+ + P ++ +++ +GS+V +CR G P P V W + +
Sbjct: 361 LHVTLSVVSYPPRILERRTKEITVHSGSTVELKCRAEGRPSPTVTWILANQTVVSESSQG 420
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
+ V DG+L L N+ + D G Y C A N G S + V P + L +
Sbjct: 421 SRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQDSLLVKIQVIAAPPVILEQRRQVIV 480
Query: 306 S--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
G + CTA G P+P+++W + + + K +F T L I +
Sbjct: 481 GTWGESLKLPCTAKGTPQPSVYWVLSDGTEVKPLQFTNSKLF---LFSNGT-LYIRNLAS 536
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT-LPIKSMAVFPCTAI 422
+D R T C A + GS R + +T ++ P I +T + + C+A
Sbjct: 537 SD-RGTYECIATSSTGSE--RRVVMLTMEERVTSPRIEAASQKRTEVNFGDKLLLNCSAT 593
Query: 423 CTPEPIIAWYFEGEALI-QNHRRNVTNDGTLV 453
P+P I W +A++ Q HR + TL+
Sbjct: 594 GEPKPQIMWRLPSKAVVDQQHRVAAGSTSTLM 625
Score = 62.9 bits (146), Expect = 7e-09
Identities = 51/180 (28%), Positives = 76/180 (42%), Gaps = 13/180 (7%)
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
S + + + A C A G P PT+ W+ R +S+ K ++ L+I
Sbjct: 284 SFTIPANSDAFLPCEAVGNPLPTIHWT----RVPSGLDLSKRKQNSRVQVLPNGTLSIQR 339
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
+ D R +CSA N G+ + L+V S PP I+ T+ S C
Sbjct: 340 VEIQD-RGQYLCSASNLFGTDHLHVTLSVVS---YPPRILERRTKEITVHSGSTVELKCR 395
Query: 421 AICTPEPIIAWYFEGEALIQNHRRN-----VTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
A P P + W + ++ + VT DGTLVL +L D G Y CVAS+ G+
Sbjct: 396 AEGRPSPTVTWILANQTVVSESSQGSRQAVVTVDGTLVLHNLSIYDRGFYKCVASNPGGQ 455
>BC109099-1|AAI09100.1| 773|Homo sapiens MUSK protein protein.
Length = 773
Score = 112 bits (269), Expect = 8e-24
Identities = 81/275 (29%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 10 EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLF 67
+AP +I PL+ A + AT C P P I W + +L+ + DT SI G L
Sbjct: 26 KAP-VITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLL 84
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ + SD G+Y C A N G A L V ++ + P + + +G VL
Sbjct: 85 TILSVED---SDDGIYCCTANNGVGGAVESCGALQVK-MKPKITRPPINVKIIEGLKAVL 140
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G+P+P+V W K L +SR+ +++ G+L I + ++ DAG+Y+C+A+N+ G
Sbjct: 141 PCTT-MGNPKPSVSWIKGDSPLR--ENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T S + L++ + ++ PE GS VT C G P+P + W + +
Sbjct: 198 TAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSI 257
Query: 248 RVKVLD---DGSLRLDNVILADEGEYSCEAENSVG 279
+ V D D L+L + G Y+C A N G
Sbjct: 258 QESVKDRVIDSRLQL---FITKPGLYTCIATNKHG 289
Score = 91.5 bits (217), Expect = 2e-17
Identities = 77/284 (27%), Positives = 122/284 (42%), Gaps = 17/284 (5%)
Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
T K+ P + T E V A TF C V P P++ W R+ + R + ++
Sbjct: 21 TEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIREN 80
Query: 255 GSL-RLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
G L + +V +D+G Y C A N VG AV + G L V P I P +V + G A
Sbjct: 81 GQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVL 140
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
CT G P+P++ W ++G+ + R+ + G L I++ K D+ C
Sbjct: 141 PCTTMGNPKPSVSW-IKGDSPL------RENSRIAVLESG--SLRIHNVQKEDA-GQYRC 190
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A N G+++ + V + I P + + S CTA P P I W
Sbjct: 191 VAKNSLGTAYSK----VVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWI 246
Query: 433 FEGEALIQNHRRNVTNDGTLVLK-DLDKSDSGTYTCVASSRHGK 475
G A+ + D + + L + G YTC+A+++HG+
Sbjct: 247 ENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE 290
Score = 68.1 bits (159), Expect = 2e-10
Identities = 67/258 (25%), Positives = 109/258 (42%), Gaps = 19/258 (7%)
Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
V+ SG + P I +V+ VA F C P+P + W+ R I +
Sbjct: 16 VAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWT----RNKILIKLF 71
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
+Y +T+L++ D+D C+A N G + G L V + P
Sbjct: 72 DTRYSIRENGQLLTILSVEDSDDG----IYCCTANNGVGGAVESCGALQV-----KMKPK 122
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459
IT P N + AV PCT + P+P ++W L +N R V G+L + ++ K
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNVQK 182
Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519
D+G Y CVA + G +S + ++ + I RA + ++ + T
Sbjct: 183 EDAGQYRCVAKNSLGT-AYSKVVKLEVEVFARI--LRAPESHNVTFGSFVTLHCTATGIP 239
Query: 520 V-TLSWSQN-NKIGSSSI 535
V T++W +N N + S SI
Sbjct: 240 VPTITWIENGNAVSSGSI 257
>AL513328-2|CAI17350.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 112 bits (269), Expect = 8e-24
Identities = 81/275 (29%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 10 EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLF 67
+AP +I PL+ A + AT C P P I W + +L+ + DT SI G L
Sbjct: 26 KAP-VITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLL 84
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ + SD G+Y C A N G A L V ++ + P + + +G VL
Sbjct: 85 TILSVED---SDDGIYCCTANNGVGGAVESCGALQVK-MKPKITRPPINVKIIEGLKAVL 140
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G+P+P+V W K L +SR+ +++ G+L I + ++ DAG+Y+C+A+N+ G
Sbjct: 141 PCTT-MGNPKPSVSWIKGDSPLR--ENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T S + L++ + ++ PE GS VT C G P+P + W + +
Sbjct: 198 TAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSI 257
Query: 248 RVKVLD---DGSLRLDNVILADEGEYSCEAENSVG 279
+ V D D L+L + G Y+C A N G
Sbjct: 258 QESVKDRVIDSRLQL---FITKPGLYTCIATNKHG 289
Score = 91.5 bits (217), Expect = 2e-17
Identities = 77/284 (27%), Positives = 122/284 (42%), Gaps = 17/284 (5%)
Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
T K+ P + T E V A TF C V P P++ W R+ + R + ++
Sbjct: 21 TEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIREN 80
Query: 255 GSL-RLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
G L + +V +D+G Y C A N VG AV + G L V P I P +V + G A
Sbjct: 81 GQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVL 140
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
CT G P+P++ W ++G+ + R+ + G L I++ K D+ C
Sbjct: 141 PCTTMGNPKPSVSW-IKGDSPL------RENSRIAVLESG--SLRIHNVQKEDA-GQYRC 190
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A N G+++ + V + I P + + S CTA P P I W
Sbjct: 191 VAKNSLGTAYSK----VVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWI 246
Query: 433 FEGEALIQNHRRNVTNDGTLVLK-DLDKSDSGTYTCVASSRHGK 475
G A+ + D + + L + G YTC+A+++HG+
Sbjct: 247 ENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE 290
Score = 68.1 bits (159), Expect = 2e-10
Identities = 67/258 (25%), Positives = 109/258 (42%), Gaps = 19/258 (7%)
Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
V+ SG + P I +V+ VA F C P+P + W+ R I +
Sbjct: 16 VAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWT----RNKILIKLF 71
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
+Y +T+L++ D+D C+A N G + G L V + P
Sbjct: 72 DTRYSIRENGQLLTILSVEDSDDG----IYCCTANNGVGGAVESCGALQV-----KMKPK 122
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459
IT P N + AV PCT + P+P ++W L +N R V G+L + ++ K
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNVQK 182
Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519
D+G Y CVA + G +S + ++ + I RA + ++ + T
Sbjct: 183 EDAGQYRCVAKNSLGT-AYSKVVKLEVEVFARI--LRAPESHNVTFGSFVTLHCTATGIP 239
Query: 520 V-TLSWSQN-NKIGSSSI 535
V T++W +N N + S SI
Sbjct: 240 VPTITWIENGNAVSSGSI 257
>AL513328-1|CAI17349.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 112 bits (269), Expect = 8e-24
Identities = 81/275 (29%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 10 EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLF 67
+AP +I PL+ A + AT C P P I W + +L+ + DT SI G L
Sbjct: 26 KAP-VITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLL 84
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ + SD G+Y C A N G A L V ++ + P + + +G VL
Sbjct: 85 TILSVED---SDDGIYCCTANNGVGGAVESCGALQVK-MKPKITRPPINVKIIEGLKAVL 140
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G+P+P+V W K L +SR+ +++ G+L I + ++ DAG+Y+C+A+N+ G
Sbjct: 141 PCTT-MGNPKPSVSWIKGDSPLR--ENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T S + L++ + ++ PE GS VT C G P+P + W + +
Sbjct: 198 TAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSI 257
Query: 248 RVKVLD---DGSLRLDNVILADEGEYSCEAENSVG 279
+ V D D L+L + G Y+C A N G
Sbjct: 258 QESVKDRVIDSRLQL---FITKPGLYTCIATNKHG 289
Score = 91.5 bits (217), Expect = 2e-17
Identities = 77/284 (27%), Positives = 122/284 (42%), Gaps = 17/284 (5%)
Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
T K+ P + T E V A TF C V P P++ W R+ + R + ++
Sbjct: 21 TEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIREN 80
Query: 255 GSL-RLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
G L + +V +D+G Y C A N VG AV + G L V P I P +V + G A
Sbjct: 81 GQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVL 140
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
CT G P+P++ W ++G+ + R+ + G L I++ K D+ C
Sbjct: 141 PCTTMGNPKPSVSW-IKGDSPL------RENSRIAVLESG--SLRIHNVQKEDA-GQYRC 190
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A N G+++ + V + I P + + S CTA P P I W
Sbjct: 191 VAKNSLGTAYSK----VVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWI 246
Query: 433 FEGEALIQNHRRNVTNDGTLVLK-DLDKSDSGTYTCVASSRHGK 475
G A+ + D + + L + G YTC+A+++HG+
Sbjct: 247 ENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE 290
Score = 68.1 bits (159), Expect = 2e-10
Identities = 67/258 (25%), Positives = 109/258 (42%), Gaps = 19/258 (7%)
Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
V+ SG + P I +V+ VA F C P+P + W+ R I +
Sbjct: 16 VAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWT----RNKILIKLF 71
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
+Y +T+L++ D+D C+A N G + G L V + P
Sbjct: 72 DTRYSIRENGQLLTILSVEDSDDG----IYCCTANNGVGGAVESCGALQV-----KMKPK 122
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459
IT P N + AV PCT + P+P ++W L +N R V G+L + ++ K
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNVQK 182
Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519
D+G Y CVA + G +S + ++ + I RA + ++ + T
Sbjct: 183 EDAGQYRCVAKNSLGT-AYSKVVKLEVEVFARI--LRAPESHNVTFGSFVTLHCTATGIP 239
Query: 520 V-TLSWSQN-NKIGSSSI 535
V T++W +N N + S SI
Sbjct: 240 VPTITWIENGNAVSSGSI 257
>AL157881-3|CAH69978.1| 867|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 867
Score = 112 bits (269), Expect = 8e-24
Identities = 81/275 (29%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 10 EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLF 67
+AP +I PL+ A + AT C P P I W + +L+ + DT SI G L
Sbjct: 26 KAP-VITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLL 84
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ + SD G+Y C A N G A L V ++ + P + + +G VL
Sbjct: 85 TILSVED---SDDGIYCCTANNGVGGAVESCGALQVK-MKPKITRPPINVKIIEGLKAVL 140
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G+P+P+V W K L +SR+ +++ G+L I + ++ DAG+Y+C+A+N+ G
Sbjct: 141 PCTT-MGNPKPSVSWIKGDSPLR--ENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T S + L++ + ++ PE GS VT C G P+P + W + +
Sbjct: 198 TAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSI 257
Query: 248 RVKVLD---DGSLRLDNVILADEGEYSCEAENSVG 279
+ V D D L+L + G Y+C A N G
Sbjct: 258 QESVKDRVIDSRLQL---FITKPGLYTCIATNKHG 289
Score = 91.5 bits (217), Expect = 2e-17
Identities = 77/284 (27%), Positives = 122/284 (42%), Gaps = 17/284 (5%)
Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
T K+ P + T E V A TF C V P P++ W R+ + R + ++
Sbjct: 21 TEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIREN 80
Query: 255 GSL-RLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
G L + +V +D+G Y C A N VG AV + G L V P I P +V + G A
Sbjct: 81 GQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVL 140
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
CT G P+P++ W ++G+ + R+ + G L I++ K D+ C
Sbjct: 141 PCTTMGNPKPSVSW-IKGDSPL------RENSRIAVLESG--SLRIHNVQKEDA-GQYRC 190
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A N G+++ + V + I P + + S CTA P P I W
Sbjct: 191 VAKNSLGTAYSK----VVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWI 246
Query: 433 FEGEALIQNHRRNVTNDGTLVLK-DLDKSDSGTYTCVASSRHGK 475
G A+ + D + + L + G YTC+A+++HG+
Sbjct: 247 ENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE 290
Score = 68.1 bits (159), Expect = 2e-10
Identities = 67/258 (25%), Positives = 109/258 (42%), Gaps = 19/258 (7%)
Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
V+ SG + P I +V+ VA F C P+P + W+ R I +
Sbjct: 16 VAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWT----RNKILIKLF 71
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
+Y +T+L++ D+D C+A N G + G L V + P
Sbjct: 72 DTRYSIRENGQLLTILSVEDSDDG----IYCCTANNGVGGAVESCGALQV-----KMKPK 122
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459
IT P N + AV PCT + P+P ++W L +N R V G+L + ++ K
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNVQK 182
Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519
D+G Y CVA + G +S + ++ + I RA + ++ + T
Sbjct: 183 EDAGQYRCVAKNSLGT-AYSKVVKLEVEVFARI--LRAPESHNVTFGSFVTLHCTATGIP 239
Query: 520 V-TLSWSQN-NKIGSSSI 535
V T++W +N N + S SI
Sbjct: 240 VPTITWIENGNAVSSGSI 257
>AL157881-2|CAH69977.1| 875|Homo sapiens muscle, skeletal, receptor
tyrosine kinase protein.
Length = 875
Score = 112 bits (269), Expect = 8e-24
Identities = 81/275 (29%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 10 EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLF 67
+AP +I PL+ A + AT C P P I W + +L+ + DT SI G L
Sbjct: 26 KAP-VITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLL 84
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ + SD G+Y C A N G A L V ++ + P + + +G VL
Sbjct: 85 TILSVED---SDDGIYCCTANNGVGGAVESCGALQVK-MKPKITRPPINVKIIEGLKAVL 140
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G+P+P+V W K L +SR+ +++ G+L I + ++ DAG+Y+C+A+N+ G
Sbjct: 141 PCTT-MGNPKPSVSWIKGDSPLR--ENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T S + L++ + ++ PE GS VT C G P+P + W + +
Sbjct: 198 TAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSI 257
Query: 248 RVKVLD---DGSLRLDNVILADEGEYSCEAENSVG 279
+ V D D L+L + G Y+C A N G
Sbjct: 258 QESVKDRVIDSRLQL---FITKPGLYTCIATNKHG 289
Score = 91.5 bits (217), Expect = 2e-17
Identities = 77/284 (27%), Positives = 122/284 (42%), Gaps = 17/284 (5%)
Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
T K+ P + T E V A TF C V P P++ W R+ + R + ++
Sbjct: 21 TEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIREN 80
Query: 255 GSL-RLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
G L + +V +D+G Y C A N VG AV + G L V P I P +V + G A
Sbjct: 81 GQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVL 140
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
CT G P+P++ W ++G+ + R+ + G L I++ K D+ C
Sbjct: 141 PCTTMGNPKPSVSW-IKGDSPL------RENSRIAVLESG--SLRIHNVQKEDA-GQYRC 190
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A N G+++ + V + I P + + S CTA P P I W
Sbjct: 191 VAKNSLGTAYSK----VVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWI 246
Query: 433 FEGEALIQNHRRNVTNDGTLVLK-DLDKSDSGTYTCVASSRHGK 475
G A+ + D + + L + G YTC+A+++HG+
Sbjct: 247 ENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE 290
Score = 68.1 bits (159), Expect = 2e-10
Identities = 67/258 (25%), Positives = 109/258 (42%), Gaps = 19/258 (7%)
Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
V+ SG + P I +V+ VA F C P+P + W+ R I +
Sbjct: 16 VAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWT----RNKILIKLF 71
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
+Y +T+L++ D+D C+A N G + G L V + P
Sbjct: 72 DTRYSIRENGQLLTILSVEDSDDG----IYCCTANNGVGGAVESCGALQV-----KMKPK 122
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459
IT P N + AV PCT + P+P ++W L +N R V G+L + ++ K
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNVQK 182
Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519
D+G Y CVA + G +S + ++ + I RA + ++ + T
Sbjct: 183 EDAGQYRCVAKNSLGT-AYSKVVKLEVEVFARI--LRAPESHNVTFGSFVTLHCTATGIP 239
Query: 520 V-TLSWSQN-NKIGSSSI 535
V T++W +N N + S SI
Sbjct: 240 VPTITWIENGNAVSSGSI 257
>AF006464-1|AAB63044.1| 869|Homo sapiens muscle specific tyrosine
kinase receptor protein.
Length = 869
Score = 112 bits (269), Expect = 8e-24
Identities = 81/275 (29%), Positives = 129/275 (46%), Gaps = 16/275 (5%)
Query: 10 EAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLF 67
+AP +I PL+ A + AT C P P I W + +L+ + DT SI G L
Sbjct: 26 KAP-VITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIRENGQLL 84
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVL 127
+ + SD G+Y C A N G A L V ++ + P + + +G VL
Sbjct: 85 TILSVED---SDDGIYCCTANNGVGGAVESCGALQVK-MKPKITRPPINVKIIEGLKAVL 140
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
C G+P+P+V W K L +SR+ +++ G+L I + ++ DAG+Y+C+A+N+ G
Sbjct: 141 PCTT-MGNPKPSVSWIKGDSPLR--ENSRIAVLESGSLRIHNVQKEDAGQYRCVAKNSLG 197
Query: 188 TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG 247
T S + L++ + ++ PE GS VT C G P+P + W + +
Sbjct: 198 TAYSKVVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWIENGNAVSSGSI 257
Query: 248 RVKVLD---DGSLRLDNVILADEGEYSCEAENSVG 279
+ V D D L+L + G Y+C A N G
Sbjct: 258 QESVKDRVIDSRLQL---FITKPGLYTCIATNKHG 289
Score = 91.5 bits (217), Expect = 2e-17
Identities = 77/284 (27%), Positives = 122/284 (42%), Gaps = 17/284 (5%)
Query: 195 TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD 254
T K+ P + T E V A TF C V P P++ W R+ + R + ++
Sbjct: 21 TEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWTRNKILIKLFDTRYSIREN 80
Query: 255 GSL-RLDNVILADEGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
G L + +V +D+G Y C A N VG AV + G L V P I P +V + G A
Sbjct: 81 GQLLTILSVEDSDDGIYCCTANNGVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVL 140
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
CT G P+P++ W ++G+ + R+ + G L I++ K D+ C
Sbjct: 141 PCTTMGNPKPSVSW-IKGDSPL------RENSRIAVLESG--SLRIHNVQKEDA-GQYRC 190
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWY 432
A N G+++ + V + I P + + S CTA P P I W
Sbjct: 191 VAKNSLGTAYSK----VVKLEVEVFARILRAPESHNVTFGSFVTLHCTATGIPVPTITWI 246
Query: 433 FEGEALIQNHRRNVTNDGTLVLK-DLDKSDSGTYTCVASSRHGK 475
G A+ + D + + L + G YTC+A+++HG+
Sbjct: 247 ENGNAVSSGSIQESVKDRVIDSRLQLFITKPGLYTCIATNKHGE 290
Score = 68.1 bits (159), Expect = 2e-10
Identities = 67/258 (25%), Positives = 109/258 (42%), Gaps = 19/258 (7%)
Query: 281 VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
V+ SG + P I +V+ VA F C P+P + W+ R I +
Sbjct: 16 VAFSGTEKLPKAPVITTPLETVDALVEEVATFMCAVESYPQPEISWT----RNKILIKLF 71
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR-GKLTVTSDDDRPPPI 399
+Y +T+L++ D+D C+A N G + G L V + P
Sbjct: 72 DTRYSIRENGQLLTILSVEDSDDG----IYCCTANNGVGGAVESCGALQV-----KMKPK 122
Query: 400 ITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDK 459
IT P N + AV PCT + P+P ++W L +N R V G+L + ++ K
Sbjct: 123 ITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLRENSRIAVLESGSLRIHNVQK 182
Query: 460 SDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTS 519
D+G Y CVA + G +S + ++ + I RA + ++ + T
Sbjct: 183 EDAGQYRCVAKNSLGT-AYSKVVKLEVEVFARI--LRAPESHNVTFGSFVTLHCTATGIP 239
Query: 520 V-TLSWSQN-NKIGSSSI 535
V T++W +N N + S SI
Sbjct: 240 VPTITWIENGNAVSSGSI 257
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.315 0.132 0.393
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 190,720,435
Number of Sequences: 224733
Number of extensions: 8919486
Number of successful extensions: 58105
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 956
Number of HSP's successfully gapped in prelim test: 1043
Number of HSP's that attempted gapping in prelim test: 30962
Number of HSP's gapped (non-prelim): 13638
length of query: 1207
length of database: 73,234,838
effective HSP length: 98
effective length of query: 1109
effective length of database: 51,211,004
effective search space: 56793003436
effective search space used: 56793003436
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 71 (32.7 bits)
- SilkBase 1999-2023 -