Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000888-TA|BGIBMGA000888-PA|IPR003599|Immunoglobulin
subtype, IPR003598|Immunoglobulin subtype 2, IPR003961|Fibronectin,
type III, IPR013098|Immunoglobulin I-set, IPR013151|Immunoglobulin,
IPR007110|Immunoglobulin-like, IPR008957|Fibronectin, type III-like
fold
(1207 letters)
Database: celegans
27,539 sequences; 12,573,161 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
U88183-2|AAM69080.1| 1273|Caenorhabditis elegans Sensory axon gu... 506 e-143
U88183-1|AAB52657.2| 1269|Caenorhabditis elegans Sensory axon gu... 506 e-143
AF041053-1|AAC38848.1| 1273|Caenorhabditis elegans SAX-3 protein. 506 e-143
Z47070-8|CAA87345.1| 5198|Caenorhabditis elegans Hypothetical pr... 161 3e-39
Z47070-7|CAA87344.1| 5175|Caenorhabditis elegans Hypothetical pr... 161 3e-39
Z47068-9|CAA87336.1| 5198|Caenorhabditis elegans Hypothetical pr... 161 3e-39
Z47068-8|CAA87335.1| 5175|Caenorhabditis elegans Hypothetical pr... 161 3e-39
AF074901-1|AAC26792.1| 5198|Caenorhabditis elegans hemicentin pr... 161 3e-39
AF003131-5|AAV34799.1| 5992|Caenorhabditis elegans Uncoordinated... 146 8e-35
AF003131-4|AAB54132.2| 6632|Caenorhabditis elegans Uncoordinated... 146 8e-35
AF003131-3|AAV34801.1| 7122|Caenorhabditis elegans Uncoordinated... 146 8e-35
AF003131-2|AAV34800.1| 7441|Caenorhabditis elegans Uncoordinated... 146 8e-35
AF003131-1|AAP68958.1| 8081|Caenorhabditis elegans Uncoordinated... 146 8e-35
U33058-1|AAB00542.1| 6632|Caenorhabditis elegans UNC-89 protein. 146 1e-34
U80438-4|AAB37634.2| 1415|Caenorhabditis elegans Uncoordinated p... 118 3e-26
U70618-1|AAB17088.1| 1415|Caenorhabditis elegans unc-40 protein. 118 3e-26
AF456361-1|AAL60232.1| 1187|Caenorhabditis elegans immunoglobuli... 111 4e-24
AC024817-49|AAF59572.3| 1187|Caenorhabditis elegans L1 cam adhes... 111 4e-24
AY130758-5|AAN61521.1| 2693|Caenorhabditis elegans 301KDa_2 prot... 106 8e-23
AY130758-4|AAN61520.1| 2708|Caenorhabditis elegans 301KDa_1 prot... 106 8e-23
AY130758-2|AAN61518.1| 18519|Caenorhabditis elegans 2MDa_2 prote... 106 8e-23
AY130758-1|AAN61517.1| 18534|Caenorhabditis elegans 2MDa_1 prote... 106 8e-23
AF022977-1|ABF71715.1| 1285|Caenorhabditis elegans Peroxidasin (... 106 1e-22
Z49938-4|CAA90189.3| 2180|Caenorhabditis elegans Hypothetical pr... 102 2e-21
Z46811-1|CAA86842.3| 2180|Caenorhabditis elegans Hypothetical pr... 102 2e-21
AF316539-1|AAK01632.1| 2200|Caenorhabditis elegans PTP-3A protein. 102 2e-21
AY724774-1|AAU21474.1| 750|Caenorhabditis elegans UNC-89-B prot... 100 5e-21
AC024817-51|AAP68914.1| 496|Caenorhabditis elegans L1 cam adhes... 98 4e-20
Z93395-7|CAH04744.1| 2389|Caenorhabditis elegans Hypothetical pr... 91 4e-18
Z93395-6|CAB07708.1| 3375|Caenorhabditis elegans Hypothetical pr... 91 4e-18
Z93395-3|CAB07706.1| 2482|Caenorhabditis elegans Hypothetical pr... 91 4e-18
Z93375-9|CAH04704.1| 2389|Caenorhabditis elegans Hypothetical pr... 91 4e-18
Z93375-8|CAB07569.1| 3375|Caenorhabditis elegans Hypothetical pr... 91 4e-18
Z93375-6|CAB07567.1| 2482|Caenorhabditis elegans Hypothetical pr... 91 4e-18
L13458-1|AAA28156.1| 2481|Caenorhabditis elegans basement membra... 91 4e-18
U49830-6|AAK31481.1| 964|Caenorhabditis elegans Neuronal igcam ... 90 1e-17
U49830-5|AAK31482.1| 1227|Caenorhabditis elegans Neuronal igcam ... 90 1e-17
U49830-4|AAU20850.1| 1196|Caenorhabditis elegans Neuronal igcam ... 90 1e-17
U50067-4|AAA93439.3| 1144|Caenorhabditis elegans Sensory axon gu... 88 4e-17
U50067-3|AAZ32801.1| 1147|Caenorhabditis elegans Sensory axon gu... 88 4e-17
U50067-2|AAY86218.1| 1328|Caenorhabditis elegans Sensory axon gu... 88 4e-17
U50067-1|AAZ32800.1| 1331|Caenorhabditis elegans Sensory axon gu... 88 4e-17
AB206670-1|BAD97389.1| 1147|Caenorhabditis elegans SAX-7 SHORTFO... 88 4e-17
AB206669-1|BAD97388.1| 1331|Caenorhabditis elegans SAX-7 LONGFOR... 88 4e-17
Z93395-4|CAB07707.1| 2295|Caenorhabditis elegans Hypothetical pr... 87 9e-17
Z93375-7|CAB07568.1| 2295|Caenorhabditis elegans Hypothetical pr... 87 9e-17
AY753200-1|AAV31408.1| 402|Caenorhabditis elegans UNC-89 protein. 85 3e-16
Z68006-8|CAA91999.1| 1328|Caenorhabditis elegans Hypothetical pr... 84 7e-16
Z68005-6|CAA91994.1| 1328|Caenorhabditis elegans Hypothetical pr... 84 7e-16
AY819766-1|AAV69856.1| 4250|Caenorhabditis elegans kettin protein. 77 6e-14
AF106579-4|AAK82895.1| 4203|Caenorhabditis elegans Kettin (droso... 77 6e-14
AF106579-2|AAM45363.1| 4447|Caenorhabditis elegans Kettin (droso... 77 6e-14
AF106579-1|AAC78200.4| 4889|Caenorhabditis elegans Kettin (droso... 77 6e-14
AB026846-1|BAA90302.2| 4219|Caenorhabditis elegans kettin protein. 77 6e-14
Z73899-13|CAM35841.1| 6629|Caenorhabditis elegans Hypothetical p... 77 1e-13
Z73899-11|CAA98082.2| 7158|Caenorhabditis elegans Hypothetical p... 77 1e-13
Z73899-10|CAA98081.2| 6839|Caenorhabditis elegans Hypothetical p... 77 1e-13
Z73897-6|CAM35838.1| 6629|Caenorhabditis elegans Hypothetical pr... 77 1e-13
Z73897-5|CAA98065.2| 7158|Caenorhabditis elegans Hypothetical pr... 77 1e-13
Z73897-4|CAA98064.2| 6839|Caenorhabditis elegans Hypothetical pr... 77 1e-13
X15423-1|CAA33463.1| 6048|Caenorhabditis elegans twitchin protein. 77 1e-13
AF016687-7|AAK72063.1| 881|Caenorhabditis elegans Hypothetical ... 77 1e-13
U49830-7|AAM98046.1| 774|Caenorhabditis elegans Neuronal igcam ... 76 2e-13
U55364-6|AAA97973.1| 2541|Caenorhabditis elegans Hypothetical pr... 73 9e-13
AF106579-3|AAM45364.1| 4369|Caenorhabditis elegans Kettin (droso... 72 3e-12
U41530-1|AAA83273.3| 636|Caenorhabditis elegans Hypothetical pr... 71 5e-12
AF016687-8|AAK72065.1| 737|Caenorhabditis elegans Hypothetical ... 71 7e-12
AL022270-1|CAB63432.1| 1270|Caenorhabditis elegans Hypothetical ... 70 9e-12
U58729-3|AAM54204.1| 955|Caenorhabditis elegans Hypothetical pr... 69 2e-11
U58729-2|AAM54203.1| 913|Caenorhabditis elegans Hypothetical pr... 69 2e-11
U58729-1|AAM54202.1| 928|Caenorhabditis elegans Hypothetical pr... 69 2e-11
AF456360-1|AAL60231.1| 928|Caenorhabditis elegans immunoglobuli... 69 2e-11
U67954-3|AAM54178.1| 436|Caenorhabditis elegans Wrapper/rega-1/... 68 4e-11
S47168-1|AAB23867.2| 947|Caenorhabditis elegans UNC-5 protein. 68 4e-11
AF456362-1|AAL60233.1| 435|Caenorhabditis elegans immunoglobuli... 68 4e-11
S47168-2|AAB23866.2| 919|Caenorhabditis elegans UNC-5 protein. 67 8e-11
AF036698-5|AAB88356.2| 567|Caenorhabditis elegans Uncoordinated... 67 8e-11
AF036698-4|AAB88355.1| 919|Caenorhabditis elegans Uncoordinated... 67 8e-11
AC024778-2|AAF60566.2| 2325|Caenorhabditis elegans Neuronal igca... 65 3e-10
U67954-6|AAV28344.1| 452|Caenorhabditis elegans Wrapper/rega-1/... 62 3e-09
U67954-5|AAM54179.1| 444|Caenorhabditis elegans Wrapper/rega-1/... 62 3e-09
AF456363-1|AAL60234.1| 443|Caenorhabditis elegans immunoglobuli... 62 3e-09
U40942-9|AAC47074.6| 703|Caenorhabditis elegans Synaptogenesis ... 61 4e-09
AY714779-1|AAU14146.1| 1338|Caenorhabditis elegans UNC-89 protein. 61 5e-09
AF003131-8|AAP68959.1| 1393|Caenorhabditis elegans Uncoordinated... 61 5e-09
AF003131-7|AAV34798.1| 1396|Caenorhabditis elegans Uncoordinated... 61 5e-09
Z68005-1|CAA91991.1| 1199|Caenorhabditis elegans Hypothetical pr... 58 3e-08
U42847-4|AAF23186.1| 1073|Caenorhabditis elegans Immunoglobulin-... 56 1e-07
AY130758-3|AAN61519.1| 10578|Caenorhabditis elegans 1MDa_1 prote... 56 2e-07
AF188751-1|AAF00548.1| 1083|Caenorhabditis elegans tyrosine kina... 55 3e-07
AF078787-11|AAC26948.2| 1083|Caenorhabditis elegans Vegf (vascul... 55 3e-07
Z81017-11|CAE47468.1| 1051|Caenorhabditis elegans Hypothetical p... 54 5e-07
Z81017-10|CAD44136.1| 1096|Caenorhabditis elegans Hypothetical p... 54 5e-07
Z81017-9|CAC70095.1| 1128|Caenorhabditis elegans Hypothetical pr... 54 5e-07
Z81017-8|CAC70094.2| 988|Caenorhabditis elegans Hypothetical pr... 54 5e-07
Z81017-7|CAB02673.2| 1040|Caenorhabditis elegans Hypothetical pr... 54 5e-07
U39761-1|AAC46934.1| 1040|Caenorhabditis elegans EGL-15 protein. 54 5e-07
AY288941-1|AAP44084.1| 987|Caenorhabditis elegans EGL-15 protein. 54 5e-07
AF148954-1|AAD37411.1| 4280|Caenorhabditis elegans myotactin for... 54 5e-07
AF148953-1|AAD37410.1| 4450|Caenorhabditis elegans myotactin for... 54 5e-07
AF040648-5|AAK21413.1| 4450|Caenorhabditis elegans Lethal protei... 54 5e-07
AF040648-4|AAK21414.2| 4280|Caenorhabditis elegans Lethal protei... 54 5e-07
U39667-6|AAC69011.2| 640|Caenorhabditis elegans Disorganized mu... 54 8e-07
AY095447-1|AAM23316.1| 640|Caenorhabditis elegans DIM-1(L) prot... 54 8e-07
AF039712-1|AAK21402.2| 239|Caenorhabditis elegans 2 (zwei) ig-d... 53 1e-06
U39667-7|AAP31442.1| 324|Caenorhabditis elegans Disorganized mu... 52 2e-06
AF500489-1|AAM21705.1| 324|Caenorhabditis elegans DIM-1 short p... 52 2e-06
U23527-1|AAC46575.2| 1147|Caenorhabditis elegans Neuronal igcam ... 52 3e-06
Z49938-5|CAD31752.1| 1467|Caenorhabditis elegans Hypothetical pr... 51 4e-06
Z46811-2|CAD31753.1| 1467|Caenorhabditis elegans Hypothetical pr... 51 4e-06
AF316540-1|AAK01633.1| 1487|Caenorhabditis elegans PTP-3B protein. 51 4e-06
AC084152-8|AAK39317.1| 541|Caenorhabditis elegans Hypothetical ... 50 8e-06
Z83235-2|CAB05773.2| 265|Caenorhabditis elegans Hypothetical pr... 48 3e-05
AF456248-1|AAL59606.1| 265|Caenorhabditis elegans secreted 2-im... 48 3e-05
U67954-4|AAM54180.1| 345|Caenorhabditis elegans Wrapper/rega-1/... 48 4e-05
AF456364-1|AAL60235.1| 344|Caenorhabditis elegans immunoglobuli... 48 4e-05
U29082-1|AAA68401.1| 251|Caenorhabditis elegans 2 (zwei) ig-dom... 46 1e-04
AF456250-1|AAL59608.1| 251|Caenorhabditis elegans secreted 2-im... 46 1e-04
Z81086-3|CAD56586.1| 711|Caenorhabditis elegans Hypothetical pr... 46 2e-04
Z81086-2|CAB03121.3| 1045|Caenorhabditis elegans Hypothetical pr... 46 2e-04
Z68116-7|CAA92170.1| 238|Caenorhabditis elegans Hypothetical pr... 46 2e-04
U00054-3|AAM48546.1| 12268|Caenorhabditis elegans Hypothetical p... 46 2e-04
U00054-2|AAA50715.2| 13100|Caenorhabditis elegans Hypothetical p... 46 2e-04
AY117398-1|AAM78593.1| 13100|Caenorhabditis elegans mesocentin p... 46 2e-04
AF456249-1|AAL59607.1| 238|Caenorhabditis elegans secreted 2-im... 46 2e-04
Z69664-7|CAA93513.2| 1159|Caenorhabditis elegans Hypothetical pr... 46 2e-04
U23452-9|AAU87820.1| 155|Caenorhabditis elegans Hypothetical pr... 46 2e-04
AC087079-12|AAK27874.2| 472|Caenorhabditis elegans Hypothetical... 44 7e-04
Z93395-1|CAB07704.1| 1160|Caenorhabditis elegans Hypothetical pr... 42 0.004
Z81045-4|CAB54202.2| 402|Caenorhabditis elegans Hypothetical pr... 41 0.006
Z81045-3|CAB02817.3| 280|Caenorhabditis elegans Hypothetical pr... 41 0.006
U29487-1|AAA68768.1| 253|Caenorhabditis elegans 2 (zwei) ig-dom... 41 0.006
AF456251-1|AAL59609.1| 253|Caenorhabditis elegans secreted 2-im... 41 0.006
AC087794-1|AAG53701.2| 304|Caenorhabditis elegans Hypothetical ... 41 0.006
AC006695-2|AAM48553.1| 724|Caenorhabditis elegans Temporarily a... 40 0.011
AC006695-1|AAU45229.1| 703|Caenorhabditis elegans Temporarily a... 40 0.011
Z68005-3|CAA91990.1| 1227|Caenorhabditis elegans Hypothetical pr... 40 0.014
AL023843-1|CAA19522.2| 260|Caenorhabditis elegans Hypothetical ... 39 0.025
Z47808-11|CAD36487.1| 928|Caenorhabditis elegans Hypothetical p... 38 0.043
Z35595-12|CAD36478.1| 928|Caenorhabditis elegans Hypothetical p... 38 0.043
AJ132946-1|CAC29084.1| 928|Caenorhabditis elegans receptor tyro... 38 0.043
Z54218-4|CAA90958.1| 1367|Caenorhabditis elegans Hypothetical pr... 37 0.076
Z49910-9|CAA90125.1| 1367|Caenorhabditis elegans Hypothetical pr... 37 0.076
Z47808-12|CAB61003.1| 902|Caenorhabditis elegans Hypothetical p... 37 0.076
Z35595-13|CAA84639.2| 902|Caenorhabditis elegans Hypothetical p... 37 0.076
AJ132947-1|CAC29085.1| 902|Caenorhabditis elegans receptor tyro... 37 0.076
U28409-1|AAC46592.3| 231|Caenorhabditis elegans Hypothetical pr... 36 0.13
AF078787-10|AAC26956.1| 352|Caenorhabditis elegans Hypothetical... 36 0.13
U64857-1|AAC25868.1| 2167|Caenorhabditis elegans Hypothetical pr... 36 0.23
AF216968-1|AAF60253.2| 658|Caenorhabditis elegans semaphorin-2a... 35 0.31
AC025726-1|AAK73921.1| 658|Caenorhabditis elegans Male abnormal... 35 0.31
Z54236-7|CAA90982.1| 1471|Caenorhabditis elegans Hypothetical pr... 35 0.40
Z83123-13|CAB05615.2| 1208|Caenorhabditis elegans Hypothetical p... 34 0.53
Z83123-2|CAB05606.1| 1014|Caenorhabditis elegans Hypothetical pr... 34 0.53
Z70680-10|CAA94577.2| 1208|Caenorhabditis elegans Hypothetical p... 34 0.53
U49956-4|AAK77620.1| 1117|Caenorhabditis elegans Variable abnorm... 34 0.53
U49956-3|AAK77621.1| 1122|Caenorhabditis elegans Variable abnorm... 34 0.53
AF040269-1|AAC38970.1| 1122|Caenorhabditis elegans Eph receptor ... 34 0.53
AF456252-1|AAL59610.1| 259|Caenorhabditis elegans secreted 2-im... 34 0.71
AL032639-10|CAA21634.1| 108|Caenorhabditis elegans Hypothetical... 33 0.93
Z69634-7|CAD01081.2| 490|Caenorhabditis elegans Hypothetical pr... 33 1.6
AC084152-4|AAR85899.1| 753|Caenorhabditis elegans Hypothetical ... 33 1.6
AC024214-10|AAF36080.1| 778|Caenorhabditis elegans Calpain fami... 33 1.6
Z83244-6|CAD18877.1| 502|Caenorhabditis elegans Hypothetical pr... 32 2.2
Z83244-5|CAB54315.1| 568|Caenorhabditis elegans Hypothetical pr... 32 2.2
Z83244-4|CAB54314.1| 562|Caenorhabditis elegans Hypothetical pr... 32 2.2
AC006607-2|AAF60372.1| 137|Caenorhabditis elegans One ig domain... 32 2.2
AC024753-2|AAF60457.2| 561|Caenorhabditis elegans Hypothetical ... 32 2.9
U80846-3|AAC70890.1| 2232|Caenorhabditis elegans Hypothetical pr... 31 3.8
Z81042-1|CAB02795.1| 1657|Caenorhabditis elegans Hypothetical pr... 31 5.0
U42834-3|AAA83583.2| 860|Caenorhabditis elegans Hypothetical pr... 31 5.0
AF132883-1|AAD25092.1| 925|Caenorhabditis elegans UNC-52/Perlec... 31 5.0
AF040648-6|AAO91708.1| 908|Caenorhabditis elegans Lethal protei... 31 5.0
Z72518-2|CAA96700.1| 613|Caenorhabditis elegans Hypothetical pr... 31 6.6
U41276-3|AAA82470.2| 517|Caenorhabditis elegans Hypothetical pr... 31 6.6
U41272-8|AAA82451.2| 243|Caenorhabditis elegans 2 (zwei) ig-dom... 31 6.6
U28993-6|AAK31498.2| 639|Caenorhabditis elegans Hypothetical pr... 31 6.6
AF316599-1|AAG38591.1| 639|Caenorhabditis elegans paracaspase p... 31 6.6
AC024759-7|AAP13762.1| 483|Caenorhabditis elegans Hypothetical ... 31 6.6
Z77656-3|CAB01140.1| 424|Caenorhabditis elegans Hypothetical pr... 30 8.7
AL110479-24|CAJ76966.1| 1084|Caenorhabditis elegans Hypothetical... 30 8.7
AL110479-23|CAB60320.2| 1254|Caenorhabditis elegans Hypothetical... 30 8.7
AF326788-1|AAK38269.1| 424|Caenorhabditis elegans CLN-3.1 protein. 30 8.7
AC024791-35|AAF60675.2| 462|Caenorhabditis elegans Innexin prot... 30 8.7
>U88183-2|AAM69080.1| 1273|Caenorhabditis elegans Sensory axon
guidance protein 3,isoform b protein.
Length = 1273
Score = 506 bits (1248), Expect = e-143
Identities = 333/1034 (32%), Positives = 510/1034 (49%), Gaps = 72/1034 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSD-----THRSIL 61
S AP IIE P+DV V+R PATLNC G PS A I WYK G V+++ +HR +L
Sbjct: 27 SNLAPVIIEHPIDVVVSRGSPATLNC--GAKPSTAKITWYKDGQPVITNKEQVNSHRIVL 84
Query: 62 PAGGLFFLRATHGR--VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
G LF L+ G+ SDAG Y+C A+N +G +S +L +A+LRE+FR+ P + Q+
Sbjct: 85 DTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQA 144
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
G+ VLEC PPRG PEP V W+K+ + L R L GNL+I ++D+G YQ
Sbjct: 145 LGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLIIDPVDRSDSGTYQ 204
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
C+A N G R S A L + KP P+D+ G++V F CRV GDP P + W+R
Sbjct: 205 CVANNMVGERVSNPARLSVFEKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRK- 263
Query: 240 GGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
MP+ R + D+ LR++ V +DEGEY C A N G + AS +L V PPS
Sbjct: 264 -NEPMPVTRAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTK 322
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG-MSRDKYHATAVFDGVTVLT 357
P +V +G A F CT G+P P FWS EG + ++FP +S D + +T+
Sbjct: 323 PADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEE 382
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT------SDDDRPPPIITNGPSNQTLPI 411
+ D+ VC+ +N AGSS + L VT + +PPP I +G NQTL +
Sbjct: 383 VRQVDE----GAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMV 438
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
S A+ PC A P P I+W +G + I + R + + G+L + DL K D+G YTC+A
Sbjct: 439 GSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIAK 498
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+ G+ WS +L V+ + N F R D S+ P PT+PI NVTDT V L W+ +
Sbjct: 499 NEDGESTWSASLTVEDHTS-NAQFVRMPDPSNFPSSPTQPIIVNVTDTEVELHWNAPSTS 557
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G+ I GY ++ +S P + W I V T Y +K L P +YMF++R E
Sbjct: 558 GAGPITGYIIQYYS---------PDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAE 608
Query: 591 NSHGLSGPSPVSDSVTVGDDSNSL-WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTI 649
N G+ PS S VT + + + + ++ +++L E I+S +
Sbjct: 609 NEKGIGTPSVSSALVTTSKPAAQVALSDKNKMDMAIAEKRLTSEQLIKLEEVKTINSTAV 668
Query: 650 KLMWEILNFYYL-EGLFIYFR-PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFL 707
+L W+ L +G +I +R P +Y T S + +++L +T YEFF+
Sbjct: 669 RLFWKKRKLEELIDGYYIKWRGPPRTNDNQYVNVT---SPSTENYVVSNLMPFTNYEFFV 725
Query: 708 IPFYK---KFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGII 764
IP++ G PSNS T + P PP ++ + +LN TT+ + W P+ NGI+
Sbjct: 726 IPYHSGVHSIHGAPSNSMDVLTAEAPPSLPPEDVRIRMLNLTTLRISWKAPKADGINGIL 785
Query: 765 TGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI--IGLGPFS 822
G+ +V+ P N + TT +A S+ + +L +G++Y +++AA + +G+ +
Sbjct: 786 KGFQIVIVG-QAPNNNRNI---TTNERAASVTLFHLVTGMTYKIRVAARSNGGVGVSHGT 841
Query: 823 QKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYV 882
+V N D+ L+ E + ++ +++F +I+IA +
Sbjct: 842 SEVIMNQDT----LEKHLAAQQENESFLYGLINKSHVPVIVIVAILIIFVVIIIAYCYWR 897
Query: 883 RKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQ 942
N K + I D G+ + N+ +P N+N + T + M N+
Sbjct: 898 NSRNSDGKDRSFIKIND--GSVHMASNNLWDVA--QNP-----NQNPMYNTAGRMTMNNR 948
Query: 943 PGVCL-SGNQTSQSKEKTNFEYDKVTHQLP-----EYAEVTSARANEWNT---NKTATSP 993
G L S +Q +Y H+ YA++T N +T N+ P
Sbjct: 949 NGQALYSLTPNAQDFFNNCDDYSGTMHRPGSEHHYHYAQLTGGPGNAMSTFYGNQYHDDP 1008
Query: 994 AAYASVTLVANTRQ 1007
+ YA+ TLV + +Q
Sbjct: 1009 SPYATTTLVLSNQQ 1022
>U88183-1|AAB52657.2| 1269|Caenorhabditis elegans Sensory axon
guidance protein 3,isoform a protein.
Length = 1269
Score = 506 bits (1248), Expect = e-143
Identities = 333/1034 (32%), Positives = 510/1034 (49%), Gaps = 72/1034 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSD-----THRSIL 61
S AP IIE P+DV V+R PATLNC G PS A I WYK G V+++ +HR +L
Sbjct: 27 SNLAPVIIEHPIDVVVSRGSPATLNC--GAKPSTAKITWYKDGQPVITNKEQVNSHRIVL 84
Query: 62 PAGGLFFLRATHGR--VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
G LF L+ G+ SDAG Y+C A+N +G +S +L +A+LRE+FR+ P + Q+
Sbjct: 85 DTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQA 144
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
G+ VLEC PPRG PEP V W+K+ + L R L GNL+I ++D+G YQ
Sbjct: 145 LGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLIIDPVDRSDSGTYQ 204
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
C+A N G R S A L + KP P+D+ G++V F CRV GDP P + W+R
Sbjct: 205 CVANNMVGERVSNPARLSVFEKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRK- 263
Query: 240 GGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
MP+ R + D+ LR++ V +DEGEY C A N G + AS +L V PPS
Sbjct: 264 -NEPMPVTRAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTK 322
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG-MSRDKYHATAVFDGVTVLT 357
P +V +G A F CT G+P P FWS EG + ++FP +S D + +T+
Sbjct: 323 PADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEE 382
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT------SDDDRPPPIITNGPSNQTLPI 411
+ D+ VC+ +N AGSS + L VT + +PPP I +G NQTL +
Sbjct: 383 VRQVDE----GAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMV 438
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
S A+ PC A P P I+W +G + I + R + + G+L + DL K D+G YTC+A
Sbjct: 439 GSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIAK 498
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+ G+ WS +L V+ + N F R D S+ P PT+PI NVTDT V L W+ +
Sbjct: 499 NEDGESTWSASLTVEDHTS-NAQFVRMPDPSNFPSSPTQPIIVNVTDTEVELHWNAPSTS 557
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G+ I GY ++ +S P + W I V T Y +K L P +YMF++R E
Sbjct: 558 GAGPITGYIIQYYS---------PDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAE 608
Query: 591 NSHGLSGPSPVSDSVTVGDDSNSL-WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTI 649
N G+ PS S VT + + + + ++ +++L E I+S +
Sbjct: 609 NEKGIGTPSVSSALVTTSKPAAQVALSDKNKMDMAIAEKRLTSEQLIKLEEVKTINSTAV 668
Query: 650 KLMWEILNFYYL-EGLFIYFR-PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFL 707
+L W+ L +G +I +R P +Y T S + +++L +T YEFF+
Sbjct: 669 RLFWKKRKLEELIDGYYIKWRGPPRTNDNQYVNVT---SPSTENYVVSNLMPFTNYEFFV 725
Query: 708 IPFYK---KFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGII 764
IP++ G PSNS T + P PP ++ + +LN TT+ + W P+ NGI+
Sbjct: 726 IPYHSGVHSIHGAPSNSMDVLTAEAPPSLPPEDVRIRMLNLTTLRISWKAPKADGINGIL 785
Query: 765 TGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI--IGLGPFS 822
G+ +V+ P N + TT +A S+ + +L +G++Y +++AA + +G+ +
Sbjct: 786 KGFQIVIVG-QAPNNNRNI---TTNERAASVTLFHLVTGMTYKIRVAARSNGGVGVSHGT 841
Query: 823 QKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYV 882
+V N D+ L+ E + ++ +++F +I+IA +
Sbjct: 842 SEVIMNQDT----LEKHLAAQQENESFLYGLINKSHVPVIVIVAILIIFVVIIIAYCYWR 897
Query: 883 RKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQ 942
N K + I D G+ + N+ +P N+N + T + M N+
Sbjct: 898 NSRNSDGKDRSFIKIND--GSVHMASNNLWDVA--QNP-----NQNPMYNTAGRMTMNNR 948
Query: 943 PGVCL-SGNQTSQSKEKTNFEYDKVTHQLP-----EYAEVTSARANEWNT---NKTATSP 993
G L S +Q +Y H+ YA++T N +T N+ P
Sbjct: 949 NGQALYSLTPNAQDFFNNCDDYSGTMHRPGSEHHYHYAQLTGGPGNAMSTFYGNQYHDDP 1008
Query: 994 AAYASVTLVANTRQ 1007
+ YA+ TLV + +Q
Sbjct: 1009 SPYATTTLVLSNQQ 1022
>AF041053-1|AAC38848.1| 1273|Caenorhabditis elegans SAX-3 protein.
Length = 1273
Score = 506 bits (1248), Expect = e-143
Identities = 333/1034 (32%), Positives = 510/1034 (49%), Gaps = 72/1034 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPA-IRWYKGGVLVVSD-----THRSIL 61
S AP IIE P+DV V+R PATLNC G PS A I WYK G V+++ +HR +L
Sbjct: 27 SNLAPVIIEHPIDVVVSRGSPATLNC--GAKPSTAKITWYKDGQPVITNKEQVNSHRIVL 84
Query: 62 PAGGLFFLRATHGR--VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS 119
G LF L+ G+ SDAG Y+C A+N +G +S +L +A+LRE+FR+ P + Q+
Sbjct: 85 DTGSLFLLKVNSGKNGKDSDAGAYYCVASNEHGEVKSNEGSLKLAMLREDFRVRPRTVQA 144
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
G+ VLEC PPRG PEP V W+K+ + L R L GNL+I ++D+G YQ
Sbjct: 145 LGGEMAVLECSPPRGFPEPVVSWRKDDKELRIQDMPRYTLHSDGNLIIDPVDRSDSGTYQ 204
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
C+A N G R S A L + KP P+D+ G++V F CRV GDP P + W+R
Sbjct: 205 CVANNMVGERVSNPARLSVFEKPKFEQEPKDMTVDVGAAVLFDCRVTGDPQPQITWKRK- 263
Query: 240 GGGNMPLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
MP+ R + D+ LR++ V +DEGEY C A N G + AS +L V PPS
Sbjct: 264 -NEPMPVTRAYIAKDNRGLRIERVQPSDEGEYVCYARNPAGTLEASAHLRVQAPPSFQTK 322
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG-MSRDKYHATAVFDGVTVLT 357
P +V +G A F CT G+P P FWS EG + ++FP +S D + +T+
Sbjct: 323 PADQSVPAGGTATFECTLVGQPSPAYFWSKEGQQDLLFPSYVSADGRTKVSPTGTLTIEE 382
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT------SDDDRPPPIITNGPSNQTLPI 411
+ D+ VC+ +N AGSS + L VT + +PPP I +G NQTL +
Sbjct: 383 VRQVDE----GAYVCAGMNSAGSSLSKAALKVTTKAVTGNTPAKPPPTIEHGHQNQTLMV 438
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVAS 470
S A+ PC A P P I+W +G + I + R + + G+L + DL K D+G YTC+A
Sbjct: 439 GSSAILPCQASGKPTPGISWLRDGLPIDITDSRISQHSTGSLHIADLKKPDTGVYTCIAK 498
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKI 530
+ G+ WS +L V+ + N F R D S+ P PT+PI NVTDT V L W+ +
Sbjct: 499 NEDGESTWSASLTVEDHTS-NAQFVRMPDPSNFPSSPTQPIIVNVTDTEVELHWNAPSTS 557
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G+ I GY ++ +S P + W I V T Y +K L P +YMF++R E
Sbjct: 558 GAGPITGYIIQYYS---------PDLGQTWFNIPDYVASTEYRIKGLKPSHSYMFVIRAE 608
Query: 591 NSHGLSGPSPVSDSVTVGDDSNSL-WEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTI 649
N G+ PS S VT + + + + ++ +++L E I+S +
Sbjct: 609 NEKGIGTPSVSSALVTTSKPAAQVALSDKNKMDMAIAEKRLTSEQLIKLEEVKTINSTAV 668
Query: 650 KLMWEILNFYYL-EGLFIYFR-PLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFL 707
+L W+ L +G +I +R P +Y T S + +++L +T YEFF+
Sbjct: 669 RLFWKKRKLEELIDGYYIKWRGPPRTNDNQYVNVT---SPSTENYVVSNLMPFTNYEFFV 725
Query: 708 IPFYK---KFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGII 764
IP++ G PSNS T + P PP ++ + +LN TT+ + W P+ NGI+
Sbjct: 726 IPYHSGVHSIHGAPSNSMDVLTAEAPPSLPPEDVRIRMLNLTTLRISWKAPKADGINGIL 785
Query: 765 TGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETI--IGLGPFS 822
G+ +V+ P N + TT +A S+ + +L +G++Y +++AA + +G+ +
Sbjct: 786 KGFQIVIVG-QAPNNNRNI---TTNERAASVTLFHLVTGMTYKIRVAARSNGGVGVSHGT 841
Query: 823 QKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFVMETWFYFLIGAIVLFKIIVIAGIIYV 882
+V N D+ L+ E + ++ +++F +I+IA +
Sbjct: 842 SEVIMNQDT----LEKHLAAQQENESFLYGLINKSHVPVIVIVAILIIFVVIIIAYCYWR 897
Query: 883 RKYNIFAKKSALPNIYDSNGTSLVTQMNIKAAVSLSHPLTSCYNKNTVTKTESLLWMENQ 942
N K + I D G+ + N+ +P N+N + T + M N+
Sbjct: 898 NSRNSDGKDRSFIKIND--GSVHMASNNLWDVA--QNP-----NQNPMYNTAGRMTMNNR 948
Query: 943 PGVCL-SGNQTSQSKEKTNFEYDKVTHQLP-----EYAEVTSARANEWNT---NKTATSP 993
G L S +Q +Y H+ YA++T N +T N+ P
Sbjct: 949 NGQALYSLTPNAQDFFNNCDDYSGTMHRPGSEHHYHYAQLTGGPGNAMSTFYGNQYHDDP 1008
Query: 994 AAYASVTLVANTRQ 1007
+ YA+ TLV + +Q
Sbjct: 1009 SPYATTTLVLSNQQ 1022
>Z47070-8|CAA87345.1| 5198|Caenorhabditis elegans Hypothetical protein
F15G9.4b protein.
Length = 5198
Score = 161 bits (391), Expect = 3e-39
Identities = 145/510 (28%), Positives = 222/510 (43%), Gaps = 30/510 (5%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA +QP + C G P P+I+W K G V D + I+ G + + T AG
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDS---DHAGK 3835
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
+ C A N G + L V ++ ++ A G+T+ L C G+P P + W
Sbjct: 3836 WSCVAENDAGV-KELEMVLDVFT-PPVVSVKSDNPIKALGETITLFC-NASGNPYPQLKW 3892
Query: 143 KKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
K G +L+FD D + G L I ++TD G Y C A NAAGT E+++ ++ + +
Sbjct: 3893 AKGG-SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASV-SVDVLVP 3950
Query: 202 PYLITGPEDVVAQ--TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LR 258
P + D+ + S+T QC G P+P + W + + V D + ++
Sbjct: 3951 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 4010
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
++NV L+D+G Y+C AEN G+ + + V P I+ + + V G +A C G
Sbjct: 4011 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS-NGGTKQVIEGELAVIECLVEG 4069
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
P P + W GNR + G+ +Y V DG +LTI + DS +CSA N A
Sbjct: 4070 YPAPQVSWLRNGNR--VETGVQGVRY----VTDG-RMLTIIEARSLDS-GIYLCSATNEA 4121
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
GS+ L V P IIT+ P T S PC P+PII+W G +
Sbjct: 4122 GSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDI 4177
Query: 439 IQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
+ DGTL ++ ++ Y C A + G V + + P I
Sbjct: 4178 KDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLE--FPVQTIVAPKISTSGN 4234
Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
++ G T I + S SWS+N
Sbjct: 4235 RYINGSEGTET-VIKCEIESESSEFSWSKN 4263
Score = 151 bits (367), Expect = 2e-36
Identities = 123/446 (27%), Positives = 189/446 (42%), Gaps = 29/446 (6%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C G+P P I WY G + ++ + A +R S +GVY C+ATNS G
Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKAD---KSYSGVYTCQATNSAG 1078
Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
+ + ++ +S + D + G P+P + W LL D
Sbjct: 1079 DNEQKTT---IRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITW------LLDD 1129
Query: 153 GDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211
+V + G+L I + + G + C A+NAAG ++ TL +H P + ++
Sbjct: 1130 KPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAG-NDTRTVTLTVHTTPTINAENQEK 1188
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
+A + +C P P LW + L + +DG+L L NV L + G +
Sbjct: 1189 IALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFV 1248
Query: 272 CEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
C+ N G S S LTV++ P I+ P V+V G C ATG PE W+ G
Sbjct: 1249 CQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNG 1308
Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
I M K+ D + L I + DKND N C N AG+S ++T
Sbjct: 1309 ----IDLKMDEKKFSV----DNLGTLRIYEADKNDIGN-YNCVVTNEAGTS----QMTTH 1355
Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-ND 449
D PP I+ + +N T + C +P + W+ G A+ + + V +D
Sbjct: 1356 VDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESD 1415
Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGK 475
GTLV++ D+ YTC AS+ GK
Sbjct: 1416 GTLVIQSASVEDATIYTCKASNPAGK 1441
Score = 141 bits (342), Expect = 2e-33
Identities = 130/510 (25%), Positives = 225/510 (44%), Gaps = 45/510 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
++C+ G P P + W + G + I + +R +D G Y C A+N
Sbjct: 3236 VHCQVTGRPVPYVTWKRNG--------KEIEQFNPVLHIR---NATRADEGKYSCIASNE 3284
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
GTA + L + F + +G++ +EC G P+P + W K G+
Sbjct: 3285 AGTAVAD--FLIDVFTKPTFETHETTFNIVEGESAKIECKID-GHPKPTISWLKGGRP-- 3339
Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-TGPE 209
F+ D+ + G L+I A++ D G Y C+A N+ G E + ++ KPY+ T +
Sbjct: 3340 FNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFK-VNVYTKPYIDETIDQ 3398
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEG 268
A G + +C V G+P P V W+R G +P R ++++ L++++V D G
Sbjct: 3399 TPKAVAGGEIILKCPVLGNPTPTVTWKR--GDDAVPNDSRHTIVNNYDLKINSVTTEDAG 3456
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
+YSC A N G ++ V P+ + N V + C T RP P++ W
Sbjct: 3457 QYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISW- 3515
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
G++ + D+Y + DG + +TIN +D +C A N AG+S + L
Sbjct: 3516 FRGDKPVYL----YDRYSISP--DG-SHITINKAKLSDG-GKYICRASNEAGTSDIDLIL 3567
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVF-PCTAICTPEPIIAWYFEGEALIQNHRRNV 446
+ PP I + L I + ++ C P+P + W G + R +
Sbjct: 3568 KILV----PPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVI 3623
Query: 447 T--NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH-----FFRAAD 499
N+ T ++++ +D G YTC A++R GK +L V SP +IH R D
Sbjct: 3624 LAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGD 3683
Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+L P + ++ D + +SW+++++
Sbjct: 3684 TITLTCP--IKLAEDIADQVMDVSWTKDSR 3711
Score = 138 bits (334), Expect = 2e-32
Identities = 122/451 (27%), Positives = 185/451 (41%), Gaps = 31/451 (6%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
Q TL C A G P P +RW G + T I A F++ + + SD GVY C
Sbjct: 3968 QSLTLQCLAQGKPVPQMRWTLNGTALTHSTP-GITVASDSTFIQINNVSL-SDKGVYTCY 4025
Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
A N G S N +V V++ +KQ +G+ V+ECL G P P V W +NG
Sbjct: 4026 AENVAG---SDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLV-EGYPAPQVSWLRNG 4081
Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
+ ++ DG L I +AR D+G Y C A N AG+ + A TL++ + P +IT
Sbjct: 4082 NRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAY-TLEVLVSPKIIT 4140
Query: 207 G-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
P + +GS + C V G P P + W + + DG+L ++ A
Sbjct: 4141 STPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEK---A 4197
Query: 266 DEGE--YSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVESGNVARFTCTATGRPEP 322
+E Y C A+N GA + + P I+ S N +N G C
Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESE-SS 4256
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
WS G P + + + + + +L+ +D+ + C+A N AG++
Sbjct: 4257 EFSWSKNG-----VPLLPSNNLIFSEDYKLIKILSTRLSDQGE----YSCTAANKAGNAT 4307
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN- 441
+ L V P I P Q + C A P+P I WY + E L
Sbjct: 4308 QKTNLNV-----GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTG 4362
Query: 442 -HRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
T +++ + S +G YTC A +
Sbjct: 4363 VDETATTKKKSVIFSSISPSQAGVYTCKAEN 4393
Score = 137 bits (331), Expect = 5e-32
Identities = 121/463 (26%), Positives = 195/463 (42%), Gaps = 28/463 (6%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + C G P+P + W + G V + G L R D+G+Y C AT
Sbjct: 4061 AVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM-LTIIEAR-SLDSGIYLCSAT 4118
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
N G+A+ TL V V + P + G L C RG P+P + W NG
Sbjct: 4119 NEAGSAQQAY-TLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV-RGYPDPIISWTLNGND 4176
Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYLIT 206
+ DG++ + G L I+ A + Y+C A+N AG T E + T+ + P + T
Sbjct: 4177 IK-DGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTI---VAPKIST 4231
Query: 207 -GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVIL 264
G + G+ +C + + + W ++ G +P + +D L ++ + L
Sbjct: 4232 SGNRYINGSEGTETVIKCEIESES-SEFSWSKN-GVPLLPSNNLIFSEDYKLIKILSTRL 4289
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
+D+GEYSC A N G + L V P I P + V G+ C A+G P+P +
Sbjct: 4290 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAI 4349
Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
W + N + G+ AT V +I+ + C A N+ S+
Sbjct: 4350 TW-YKDNELLTNTGVDET---ATTKKKSVIFSSISPSQAG----VYTCKAENWVASTEED 4401
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
L V PP ++ + T P + C A PEP+I+W + IQN+ +
Sbjct: 4402 IDLIVMI----PPEVVPERMNVSTNP-RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEK 4456
Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
TL ++++ D G Y C+A S G+ + + L+V+ P
Sbjct: 4457 YQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP 4499
Score = 136 bits (329), Expect = 9e-32
Identities = 126/472 (26%), Positives = 200/472 (42%), Gaps = 23/472 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V + E+P I +V+V + A L+C + IRW + G V + + P G
Sbjct: 514 VETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNG 573
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+ H +DAGVY C A N+ G + +R L + + ++ P+ + V
Sbjct: 574 TLKI---HHVTRADAGVYECMARNAGGMS-TRKMRLDI-MEPPSVKVTPQDVYFNMREGV 628
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C G P+P V+W G+ LL D ++ D L I+DA D G Y+C A +
Sbjct: 629 NLSC-EAMGDPKPEVHWYFKGRHLLNDYKYQVGQ-DSKFLYIRDATHHDEGTYECRAMSQ 686
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWRRSAGGGNM 244
AG L + P + ++ G V+F+C+ + G P P + W ++
Sbjct: 687 AGQARDT-TDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIK 745
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
P +K+ ++G L + D G YSC EN G L+V P+I SP++V V
Sbjct: 746 PDDYIKI-NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRV 804
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
C A G P P + W +GN ++ ++ +Y T + DG L I D
Sbjct: 805 NIERQVTLQCLAVGIPPPEIEWQ-KGN--VLLATLNNPRY--TQLADG--NLLITDAQIE 857
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC- 423
D + C A N G L VT P++ + P + L C +
Sbjct: 858 D-QGQFTCIARNTYGQQSQSTTLMVTG---LVSPVLGHVPPEEQLIEGQDLTLSCVVVLG 913
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474
TP+P I W + + + + + G+L+ L+ + D G YTC+A S G
Sbjct: 914 TPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAG 965
Score = 135 bits (327), Expect = 2e-31
Identities = 129/474 (27%), Positives = 202/474 (42%), Gaps = 28/474 (5%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
++++ + T H TL+C A G P P I W+K G + + I+P G L +
Sbjct: 2291 MLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKI 2350
Query: 74 GRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
R+ DAG Y CEA NS G+ + + + E P +S Q + VV+ C P
Sbjct: 2351 TRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC-PV 2409
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT--RE 190
P + W K G+ L D + +G L + R+TD+ +Y CIA N AGT R+
Sbjct: 2410 YARPPAKITWLKAGKPLQSDKFVKTS-ANGQKLYLFKLRETDSSKYTCIATNEAGTDKRD 2468
Query: 191 SAIATL--KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
++ L +P ++ + +G+ T C G P P + W + G P R
Sbjct: 2469 FKVSMLVAPSFDEPNIV---RRITVNSGNPSTLHCPAKGSPSPTITWLKD-GNAIEPNDR 2524
Query: 249 VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSPNSVNVES 306
D G L++ +D+G Y+C A NSVG+ L V PP I+ +V V
Sbjct: 2525 YVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIE 2584
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G + C + + W +G TI + D + + ++ K+DS
Sbjct: 2585 GFSSELFCDSNS-TGVDVEWQKDG-LTINQDTLRGDSF--IQIPSSGKKMSFLSARKSDS 2640
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN---QTLPIKSMAVFPCTAIC 423
C N AG + KL + +D PP I++ S+ QT+ C
Sbjct: 2641 -GRYTCIVRNPAGEA---RKLFDFAVND--PPSISDELSSANIQTIVPYYPVEINCVVSG 2694
Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
+P P + W F+ + L + +TN+G TL + +GTYTC A + GK
Sbjct: 2695 SPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGK 2748
Score = 134 bits (323), Expect = 5e-31
Identities = 135/505 (26%), Positives = 215/505 (42%), Gaps = 57/505 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGL 66
G P IIE P V V + TL C A G P P I W KG VL+ +++ + L G L
Sbjct: 790 GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGNL 849
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTV 125
T ++ D G + C A N+YG +S++ TL V ++ P +Q +G +
Sbjct: 850 LI---TDAQI-EDQGQFTCIARNTYG-QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDL 904
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184
L C+ G+P+P++ W K+ + + + + + GG+L+ ++ D G+Y CIA +
Sbjct: 905 TLSCVVVLGTPKPSIVWIKDDKPV--EEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVS 962
Query: 185 AAGTRESAIATLKIHIKPYLITGPED-----------------VVAQT-----GSSVTFQ 222
AG I +++ KP + PE VV T G
Sbjct: 963 PAGNSTLHI-NVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
C V G P P + W G P R V D +L + + G Y+C+A NS G
Sbjct: 1022 CVVSGTPPPIITWYLD-GRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDN 1080
Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
+ + + P I+ +S N+ ++ C G P+P + W ++
Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD------------ 1128
Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
DK V + LTI + ++ R T C A N AG+ TVT P I
Sbjct: 1129 DKPFTEGVVNEDGSLTIPNVNE-AHRGTFTCHAQNAAGND----TRTVTLTVHTTPTI-- 1181
Query: 402 NGPSNQTLPIKS-MAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDK 459
N + + + +++ V C A P P+ W +EGE + Q + DG LVL+++
Sbjct: 1182 NAENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKL 1241
Query: 460 SDSGTYTCVASSRHGKYVWSGALLV 484
++G + C S+ G+ S L V
Sbjct: 1242 ENTGVFVCQVSNLAGEDSLSYTLTV 1266
Score = 133 bits (322), Expect = 6e-31
Identities = 139/501 (27%), Positives = 212/501 (42%), Gaps = 65/501 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT +P + P + + Q TL+C G+P P+I W K V I G
Sbjct: 881 VTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGG 940
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL---REEFRLEPES----- 116
L LR + + D G Y C A + G N+TLH+ V + EF +PE
Sbjct: 941 SLLRLRGGNPK---DEGKYTCIAVSPAG-----NSTLHINVQLIKKPEFVYKPEGGIVFK 992
Query: 117 --------KQSA---------QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
K A G+ + C+ G+P P + W +G+ + +SR
Sbjct: 993 PTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVS-GTPPPIITWYLDGRPIT--PNSRDFT 1049
Query: 160 VDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
V N L+++ A ++ +G Y C A N+AG E T++I P + G
Sbjct: 1050 VTADNTLIVRKADKSYSGVYTCQATNSAGDNEQK-TTIRIMNTPMISPGQSSFNMVVDDL 1108
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
T C V GDP P + W + P V +DGSL + NV A G ++C A+N+
Sbjct: 1109 FTIPCDVYGDPKPVITWLLD----DKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAA 1164
Query: 279 GAVSASGYLTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR--TII 335
G + + LTV+ P+IN + + +++ ++ C A P P W+ EG + + +
Sbjct: 1165 GNDTRTVTLTVHTTPTINAENQEKIALQNDDIV-LECPAKALPPPVRLWTYEGEKIDSQL 1223
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
P R+ DG VL K ++ VC N AG + LTV
Sbjct: 1224 IPHTIRE--------DGALVL---QNVKLENTGVFVCQVSNLAGEDSLSYTLTV----HE 1268
Query: 396 PPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLV 453
P II+ P + +K + PC A PE I W G L + ++ +V N GTL
Sbjct: 1269 KPKIISEVPGVVDV-VKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR 1327
Query: 454 LKDLDKSDSGTYTCVASSRHG 474
+ + DK+D G Y CV ++ G
Sbjct: 1328 IYEADKNDIGNYNCVVTNEAG 1348
Score = 133 bits (321), Expect = 8e-31
Identities = 129/477 (27%), Positives = 195/477 (40%), Gaps = 40/477 (8%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D YV E P ++ + V + T+ C G+P P + W K G SD +
Sbjct: 3118 DTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTK 3177
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSA 120
L LR T +D G Y C ATN G +++ T V VL R+E E + Q
Sbjct: 3178 LSYL-HLRET---TLADGGTYTCIATNKAGESQT---TTDVEVLVPP-RIEDEERVLQGK 3229
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+G+T ++ C G P P V WK+NG+ + + + V L I++A + D G+Y C
Sbjct: 3230 EGNTYMVHC-QVTGRPVPYVTWKRNGKEI-----EQFNPV----LHIRNATRADEGKYSC 3279
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
IA N AGT A + + KP T G S +C++ G P P + W + G
Sbjct: 3280 IASNEAGT-AVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLK--G 3336
Query: 241 GGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS- 298
G + + + G +L + D G Y+C A NS G + VY P I+ +
Sbjct: 3337 GRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETI 3396
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ +G C G P PT+ W G+ + P SR + +D L I
Sbjct: 3397 DQTPKAVAGGEIILKCPVLGNPTPTVTWK-RGDDAV--PNDSR--HTIVNNYD----LKI 3447
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N D+ C AVN AG+ V P + G + +
Sbjct: 3448 NSVTTEDA-GQYSCIAVNEAGNLTTHYAAEVIG----KPTFVRKGGNLYEVIENDTITMD 3502
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474
C P P I+W+ + + R +++ DG+ + + SD G Y C AS+ G
Sbjct: 3503 CGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAG 3559
Score = 128 bits (310), Expect = 2e-29
Identities = 129/484 (26%), Positives = 191/484 (39%), Gaps = 35/484 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
V + T++C P P+I W++G V SI P G + SD G
Sbjct: 3493 VIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAK---LSDGGK 3549
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVY 141
Y C A+N GT+ + L + V + + A T+ LEC P G P+P+V
Sbjct: 3550 YICRASNEAGTS-DIDLILKILVPPKIDKSNIIGNPLAIVARTIYLEC-PISGIPQPDVI 3607
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
W KNG + DSR+ L I++ + TD GRY C A N G + +
Sbjct: 3608 WTKNGMDINMT-DSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSP 3666
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVG-----GDPLPDVLWRRSAGGGNMPL-GRVKVLDD 254
+ I G + + + G ++T C + D + DV W + + + L V + DD
Sbjct: 3667 PEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDD 3726
Query: 255 G-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVAR 311
G L + L + G Y+C A N G S + + PP I++S N V V
Sbjct: 3727 GRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTI 3786
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
C TG P P++ W G D + V G VL I TD +D
Sbjct: 3787 MRCAVTGHPFPSIKWLKNGKEV-------TDDENIRIVEQG-QVLQILRTD-SDHAGKWS 3837
Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
C A N AG + L V + PP+++ N + C A P P + W
Sbjct: 3838 CVAENDAGVKELEMVLDVFT-----PPVVSVKSDNPIKALGETITLFCNASGNPYPQLKW 3892
Query: 432 YFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
G + + R L + L K+D G YTC A + G ++ VD +
Sbjct: 3893 AKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAG--TSEASVSVDVLVP 3950
Query: 490 PNIH 493
P I+
Sbjct: 3951 PEIN 3954
Score = 124 bits (299), Expect = 4e-28
Identities = 109/455 (23%), Positives = 187/455 (41%), Gaps = 20/455 (4%)
Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
T+ + P +NC GSP P + W + D+ L G L+ +V AG
Sbjct: 2679 TIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET-LKIVRSQVEH-AG 2736
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
Y CEA N+ G AR ++ + V F E E + GDT++L C P +VY
Sbjct: 2737 TYTCEAQNNVGKAR-KDFLVRVTA-PPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVY 2794
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W + +++ + + + L + + + D G Y C A N AG + + I
Sbjct: 2795 WHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIE-T 2853
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
PY + + G +T C G P P +L+ + N V ++ +L +DN
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLN-ESDEVDII-GSTLVIDN 2911
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
EG Y+C AEN G + V PP ++ +V V++G+ C
Sbjct: 2912 PQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSG 2971
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
+ WS + + ++ + ++ + T D D + C AVN AG +
Sbjct: 2972 VHITWSRQFGKDGQLDMRAQSSSDKSKLY--IMQATPEDAD------SYSCIAVNDAGGA 3023
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
++TV + PP I + S + + PC P P I+W+ +G+ +++
Sbjct: 3024 EAVFQVTVNT----PPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEM 3079
Query: 442 HRRNV-TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
D +L + ++ + G YTCVA ++ G+
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGR 3114
Score = 123 bits (297), Expect = 7e-28
Identities = 115/417 (27%), Positives = 170/417 (40%), Gaps = 27/417 (6%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
DAG Y C ++ G + E F + S G+ L C R + E
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPL--GEAAFLHC-STRSAGEV 549
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
+ W + G T+ F+G + G L I + DAG Y+C+ARNA G + L I
Sbjct: 550 EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMR-LDI 607
Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257
P + P+DV V C GDP P+V W G + + +V D L
Sbjct: 608 MEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFK-GRHLLNDYKYQVGQDSKFL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TA 316
+ + DEG Y C A + G + L + PP + + N + V G+ F C T
Sbjct: 667 YIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTI 726
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G+P P + W G + +I P D Y + +G L I K++ C N
Sbjct: 727 RGKPHPKIRWFKNG-KDLIKP----DDY--IKINEGQ--LHIMGA-KDEDAGAYSCVGEN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG L+V R P II + P + I+ C A+ P P I W +G
Sbjct: 777 MAGKDVQVANLSV----GRVPTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGN 830
Query: 437 ALI---QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
L+ N R DG L++ D D G +TC+A + +G+ S L+V ++P
Sbjct: 831 VLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP 887
Score = 121 bits (292), Expect = 3e-27
Identities = 109/470 (23%), Positives = 184/470 (39%), Gaps = 32/470 (6%)
Query: 6 VTSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT P I T + + CR G P P I W+ G ++ +
Sbjct: 3029 VTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMP--GVTYKQ 3086
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G LR + + + + G Y C A N G A ++ + ++ + E + +G
Sbjct: 3087 GDLSLRIDNIKPNQE-GRYTCVAENKAGRAE-QDTYVEISE-PPRVVMASEVMRVVEGRQ 3143
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ C G+PEP V W K+G+ + D L +++ D G Y CIA N
Sbjct: 3144 TTIRC-EVFGNPEPVVNWLKDGEP--YTSDLLQFSTKLSYLHLRETTLADGGTYTCIATN 3200
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG ++ +++ + P + + + G++ C+V G P+P V W+R+
Sbjct: 3201 KAGESQTT-TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN------ 3253
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
G+ + L + N ADEG+YSC A N G A + V+ P+ + N+
Sbjct: 3254 --GKEIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNI 3311
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G A+ C G P+PT+ W ++G R + D + D + +L D
Sbjct: 3312 VEGESAKIECKIDGHPKPTISW-LKGGRP-----FNMDNIILSPRGDTLMILKAQRFD-- 3363
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
C A N G S K+ V + P I + C +
Sbjct: 3364 --GGLYTCVATNSYGDSEQDFKVNVYT----KPYIDETIDQTPKAVAGGEIILKCPVLGN 3417
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P + W +A+ + R + N+ L + + D+G Y+C+A + G
Sbjct: 3418 PTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEAG 3467
Score = 120 bits (288), Expect = 8e-27
Identities = 121/466 (25%), Positives = 184/466 (39%), Gaps = 32/466 (6%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
T+ C G P P I W +L ++ G + + + G + C A N
Sbjct: 1110 TIPCDVYGDPKPVITW----LLDDKPFTEGVVNEDGSLTIPNVN---EAHRGTFTCHAQN 1162
Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
+ G +R TL V E + K + Q D +VLEC P + P P W G+ +
Sbjct: 1163 AAGND-TRTVTLTVHTT-PTINAENQEKIALQNDDIVLEC-PAKALPPPVRLWTYEGEKI 1219
Query: 150 LFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
D H + + G LV+Q+ + + G + C N AG +S TL +H KP +I+
Sbjct: 1220 --DSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAG-EDSLSYTLTVHEKPKIISEV 1276
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
VV G ++ CR G P W ++ M + V + G+LR+ D
Sbjct: 1277 PGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLRIYEADKNDI 1336
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTCTATGRPEPTMFW 326
G Y+C N G + ++ V +PP I S + N G+ C P ++ W
Sbjct: 1337 GNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTW 1396
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
G I G Y V + L I D+ C A N AG + +
Sbjct: 1397 FRRG----IAIGTDTKGY----VVESDGTLVIQSASVEDA-TIYTCKASNPAGKAEANLQ 1447
Query: 387 LTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445
+TV S D + P ++T ++ P C P P I+WY + LI +
Sbjct: 1448 VTVIASPDIKDPDVVTQESIKESHPFS----LYCPVFSNPLPQISWYLNDKPLIDDKTSW 1503
Query: 446 VTNDGTLVLKDLDK--SDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
T+D L +DSG Y CVA + G+ S + V P+N
Sbjct: 1504 KTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLN 1549
Score = 120 bits (288), Expect = 8e-27
Identities = 121/472 (25%), Positives = 188/472 (39%), Gaps = 38/472 (8%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E PY ++Q + + TL+C A G+P P I + K G + I+ G +
Sbjct: 2852 ETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--GSTLVI 2909
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
V G Y C A N G RS + +L + E + + GD + LEC
Sbjct: 2910 DNPQKEVE---GRYTCIAENKAG--RSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLEC 2964
Query: 130 LPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
P + ++ W + G+ D ++ D L I A DA Y CIA N AG
Sbjct: 2965 -PIEDTSGVHITWSRQFGKDGQLDMRAQSSS-DKSKLYIMQATPEDADSYSCIAVNDAGG 3022
Query: 189 RESAIATLKIHIKPYLIT---GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
E A+ + ++ P + ++VA T ++ CR G P P++ W
Sbjct: 3023 AE-AVFQVTVNTPPKIFGDSFSTTEIVADT--TLEIPCRTEGIPPPEISWFLDGKPILEM 3079
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
G D SLR+DN+ EG Y+C AEN G Y+ + +PP + ++ + V
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVV 3139
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G C G PEP + W +G P S +T ++ L + +T D
Sbjct: 3140 EGRQTTIRCEVFGNPEPVVNWLKDGE-----PYTSDLLQFSTK----LSYLHLRETTLAD 3190
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
T C A N AG S T T + PP I + + + C P
Sbjct: 3191 G-GTYTCIATNKAGES-----QTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244
Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
P + W G+ + Q + L +++ ++D G Y+C+AS+ G V
Sbjct: 3245 VPYVTWKRNGKEIEQ-------FNPVLHIRNATRADEGKYSCIASNEAGTAV 3289
Score = 118 bits (285), Expect = 2e-26
Identities = 128/483 (26%), Positives = 203/483 (42%), Gaps = 61/483 (12%)
Query: 23 VARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V R + C+ G P P IRW+K G ++ + G L + G DAG
Sbjct: 713 VGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIM----GAKDEDAG 768
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNV 140
Y C N G +++V R +E P + + V L+CL G P P +
Sbjct: 769 AYSCVGENMAGKDVQ---VANLSVGRVPTIIESPHTVRVNIERQVTLQCLAV-GIPPPEI 824
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH- 199
W+K L + R + GNL+I DA+ D G++ CIARN G ++S TL +
Sbjct: 825 EWQKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYG-QQSQSTTLMVTG 883
Query: 200 -IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGR---VKVLDD 254
+ P L P + G +T C V G P P ++W + + P+ +K+
Sbjct: 884 LVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKD----DKPVEEGPTIKIEGG 939
Query: 255 GS-LRLDNVILADEGEYSCEAENSVG--AVSASGYLT-----VYDPP-SINLSPNSVNVE 305
GS LRL DEG+Y+C A + G + + L VY P I P ++
Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999
Query: 306 SGNVA--------------RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
+VA C +G P P + W ++G I P SRD + TA
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRP--ITPN-SRD-FTVTA--- 1052
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L + DK+ S C A N AG + + + + + P+I+ G S+ + +
Sbjct: 1053 -DNTLIVRKADKSYS-GVYTCQATNSAGDNEQKTTIRIMN-----TPMISPGQSSFNMVV 1105
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
+ PC P+P+I W + + + V DG+L + +++++ GT+TC A +
Sbjct: 1106 DDLFTIPCDVYGDPKPVITWLLDDKPFTEG---VVNEDGSLTIPNVNEAHRGTFTCHAQN 1162
Query: 472 RHG 474
G
Sbjct: 1163 AAG 1165
Score = 116 bits (278), Expect = 1e-25
Identities = 125/466 (26%), Positives = 191/466 (40%), Gaps = 28/466 (6%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++TV + TL C + I W G +++T AGG F L + D
Sbjct: 2015 ELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGVQTLAGGRF-LHIVSAKT-DD 2072
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
G Y C TN G A ++ L V V E + +++VL C G P P
Sbjct: 2073 HGSYACTVTNEAGVA-TKTFNLFVQVPPTIVN-EGGEYTVIENNSLVLPC-EVTGKPNPV 2129
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
V W K+G+ + D S L +G I A G Y C+A+N GT E + + I
Sbjct: 2130 VTWTKDGRPV-GDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEISF-DVDII 2187
Query: 200 IKPYLITGPEDVV-AQTGSSVTFQCRVGGDP--LPDVLWRRSAGGGNMPLGRVKVL---D 253
+P + G +++V A G ++ F+C + D ++W R+ ++ ++ +
Sbjct: 2188 TRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSN 2247
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVA 310
D L + NV DEG+YSC +N G S TV PP+I + N VE V
Sbjct: 2248 DRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVT 2307
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
+C ATG+PEP + W +G I ++ + + + + I + D
Sbjct: 2308 -LSCPATGKPEPDITWFKDG-EAIHIENIADIIPNGELNGNQLKITRIKEGD----AGKY 2361
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AGS + V + P I +G PS+ V C P I
Sbjct: 2362 TCEADNSAGSVEQDVNVNVIT----IPKIEKDGIPSDYESQQNERVVISCPVYARPPAKI 2417
Query: 430 AWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
W G+ L + N L L L ++DS YTC+A++ G
Sbjct: 2418 TWLKAGKPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAG 2463
Score = 110 bits (264), Expect = 7e-24
Identities = 114/460 (24%), Positives = 188/460 (40%), Gaps = 45/460 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C SP ++ W++ G+ + +DT ++ + G +++ DA +Y C+A+N
Sbjct: 1382 LKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE---DATIYTCKASNP 1438
Query: 91 YGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
G A A L V V+ +P+ + + L C P +P P + W N +
Sbjct: 1439 AGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYC-PVFSNPLPQISWYLNDK 1494
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT-----RESAIATLKIHIKP 202
L+ D S D L + A+ TD+G Y+C+ARNAAG + I L +
Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESK 1554
Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSLRL 259
Y + V A+ G VT C V G P+P + W G G D +L
Sbjct: 1555 Y----KKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHF 1610
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TATG 318
D+V + EG Y C A++ + L+V P + N + V G +C T
Sbjct: 1611 DSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDN-LEVFLGKDISLSCDLQTE 1669
Query: 319 RPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
+ T F WS+ G+ + D+ + L I D K ++ +C N
Sbjct: 1670 SDDKTTFVWSINGSES--------DRPDNVQIPSDGHRLYITDA-KPENNGKYMCRVTNS 1720
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + + T+T D PP + +NQ L + + C P+P + W +G
Sbjct: 1721 AG----KAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGN 1776
Query: 437 ALIQNHRRNVTNDGTLVLKDLDK--SDSGTYTCVASSRHG 474
+ ++ D +L L ++K S +C A ++ G
Sbjct: 1777 DV----DKSWLFDESLSLLRIEKLTGKSAQISCTAENKAG 1812
Score = 104 bits (249), Expect = 4e-22
Identities = 98/387 (25%), Positives = 144/387 (37%), Gaps = 20/387 (5%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I P +T + +L C G P P I W G + + + A G +
Sbjct: 4139 ITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAE 4198
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R H +Y C A N G A + + V + ++G V++C
Sbjct: 4199 ER-HL---IYECTAKNDAG-ADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES 4253
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
S E + W KNG LL ++ + D + I R +D G Y C A N AG
Sbjct: 4254 ESSEFS--WSKNGVPLL-PSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQK- 4309
Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVL 252
L + + P ++ P V G VT C G P P + W + N +
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT 4369
Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
S+ ++ + G Y+C+AEN V + L V PP + +V+
Sbjct: 4370 KKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFL 4429
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
+C ATG PEP + W + N I + +KY T L I + +D C
Sbjct: 4430 SCNATGIPEPVISWMRDSNIAI----QNNEKYQILG-----TTLAIRNVLPDDD-GFYHC 4479
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPI 399
A + AG KL V DRP PI
Sbjct: 4480 IAKSDAGQKIATRKLIVNKPSDRPAPI 4506
Score = 98.3 bits (234), Expect = 3e-20
Identities = 109/363 (30%), Positives = 152/363 (41%), Gaps = 31/363 (8%)
Query: 6 VTSGEAPYII-EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63
+T E P II E P V V + + CRA G P W K G+ L + + S+
Sbjct: 1264 LTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNL 1323
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQ 121
G L A +D G Y C TN GT++ T HV V L + +
Sbjct: 1324 GTLRIYEAD----KNDIGNYNCVVTNEAGTSQ---MTTHVDVQEPPIILPSTQTNNTAVV 1376
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQC 180
GD V L+C SP +V W + G + D++ ++V+ G LVIQ A DA Y C
Sbjct: 1377 GDRVELKCY-VEASPPASVTWFRRG--IAIGTDTKGYVVESDGTLVIQSASVEDATIYTC 1433
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ----TGSSVTFQCRVGGDPLPDVLWR 236
A N AG E A L++ + DVV Q + C V +PLP + W
Sbjct: 1434 KASNPAGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWY 1490
Query: 237 RSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
+ K DD L + + D G Y C A N+ G S S + V P ++
Sbjct: 1491 LNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNL 1550
Query: 296 NLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH-ATAVFDG 352
+ S V + G C +G P P + W V+G T++ PG KY AT DG
Sbjct: 1551 DESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDG--TVVEPG---KKYKGATLSNDG 1605
Query: 353 VTV 355
+T+
Sbjct: 1606 LTL 1608
Score = 97.5 bits (232), Expect = 5e-20
Identities = 87/342 (25%), Positives = 139/342 (40%), Gaps = 23/342 (6%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IARNAAGTRESAIATLK 197
+YW K G+ ++ G H D I + DAG Y+C I+ N + ++ + T +
Sbjct: 460 IYWVKTGEDII-GGPLFYHNTDTSVWTIPELSLKDAGEYECRVISNNGNYSVKTRVETRE 518
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR-SAGGGNMPLGRVKVLDDGS 256
P I G +V G + C ++ W R A N P + +G+
Sbjct: 519 ---SPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGP-NTERNPTNGT 574
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
L++ +V AD G Y C A N+ G + L + +PPS+ ++P V +C A
Sbjct: 575 LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEA 634
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G P+P + W +G ++ KY V L I D +D T C A++
Sbjct: 635 MGDPKPEVHWYFKGRHL-----LNDYKYQ---VGQDSKFLYIRDATHHD-EGTYECRAMS 685
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEG 435
AG + L + + PP + + + F C I P P I W+ G
Sbjct: 686 QAGQARDTTDLMLAT-----PPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNG 740
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
+ LI+ N+G L + D+G Y+CV + GK V
Sbjct: 741 KDLIKPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDV 782
Score = 93.5 bits (222), Expect = 8e-19
Identities = 106/471 (22%), Positives = 181/471 (38%), Gaps = 34/471 (7%)
Query: 10 EAPYIIEQPLDVT--VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
E P +E + + + P L C+ G+P P + W G +D +S L L
Sbjct: 1734 EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDG----NDVDKSWLFDESLS 1789
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVV 126
LR ++ + C A N GTA SR+ + + F+ E + + + +T+
Sbjct: 1790 LLRIE--KLTGKSAQISCTAENKAGTA-SRDFFIQ-NIAAPTFKNEGDQETIFRESETIT 1845
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L+C P + + W K G L + D+ + +D L I +A + Y C+A N A
Sbjct: 1846 LDC--PVSLGDFQITWMKQGLPLT-ENDA-IFTLDNTRLTILNANRDHEDIYTCVANNTA 1901
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G + S + + + P + + G + C G+P P W G++P
Sbjct: 1902 G-QVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKW--DFNQGDLPK 1958
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNV 304
V V ++ ++ ++NV G Y C A N VG + + V P L+ + + V
Sbjct: 1959 EAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTV 2018
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
C + W+V G P ++ + G L I K
Sbjct: 2019 NLTRSITLECDVDDAIGVGISWTVNGK-----PFLA--ETDGVQTLAGGRFLHIVSA-KT 2070
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D + C+ N AG + L V + PP I N T+ + V PC
Sbjct: 2071 DDHGSYACTVTNEAGVATKTFNLFV-----QVPPTIVNEGGEYTVIENNSLVLPCEVTGK 2125
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
P P++ W +G + V ++G + + + G+Y C+A + G
Sbjct: 2126 PNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVG 2176
Score = 92.7 bits (220), Expect = 1e-18
Identities = 114/453 (25%), Positives = 176/453 (38%), Gaps = 45/453 (9%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
S S W K GV ++ + L + +T SD G Y C A N G A ++
Sbjct: 4253 SESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTR---LSDQGEYSCTAANKAGNA-TQ 4308
Query: 98 NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
L+V V + P ++ +GD V L C G P+P + W K+ + L G
Sbjct: 4309 KTNLNVGVAPKIME-RPRTQVVHKGDQVTLWC-EASGVPQPAITWYKDNELLTNTGVDET 4366
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217
+++ + AG Y C A N + E I L + I P ++ +V
Sbjct: 4367 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDI-DLIVMIPPEVVPERMNVSTNPRQ 4425
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
+V C G P P + W R + + ++L +L + NV+ D+G Y C A++
Sbjct: 4426 TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGT-TLAIRNVLPDDDGFYHCIAKSD 4484
Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
G A+ L V P P + VE C G+P+ T + +I
Sbjct: 4485 AGQKIATRKLIVNKPSD---RPAPIWVE--------CDEKGKPKKTEY--------MIDR 4525
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
G + D D +L D + + +I Y R TV P
Sbjct: 4526 GDTPD--------DNPQLLPWKDVEDSSLNGSIA-----YRCMPGPRSSRTVLLH--AAP 4570
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
I P N T I ++ C+A P P I W +G+ LI++ + + V +
Sbjct: 4571 QFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAYSHLKVTLN- 4627
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
SDSG YTC+A + G S + VD+ I P
Sbjct: 4628 STSDSGEYTCMAQNSVGSSTVSAFINVDNNILP 4660
Score = 89.8 bits (213), Expect = 1e-17
Identities = 124/473 (26%), Positives = 194/473 (41%), Gaps = 62/473 (13%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGL 66
G AP I+E+P V + TL C A G P PAI WYK L+ + + +
Sbjct: 4315 GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSV 4374
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
F + S AGVY C+A N + + + L + ++ E E + + TV
Sbjct: 4375 IFSSIS----PSQAGVYTCKAEN-WVASTEEDIDL-IVMIPPEVVPERMNVSTNPRQTVF 4428
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G PEP + W ++ + + + + + G L I++ D G Y CIA++ A
Sbjct: 4429 LSC-NATGIPEPVISWMRDSNIAIQNNEK--YQILGTTLAIRNVLPDDDGFYHCIAKSDA 4485
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGNM 244
G + IAT K+ ++ P D A + +C G P ++ R N
Sbjct: 4486 GQK---IATRKL-----IVNKPSDRPA----PIWVECDEKGKPKKTEYMIDRGDTPDDNP 4533
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
L K ++D SL N +A Y C + +S + ++ P + P +
Sbjct: 4534 QLLPWKDVEDSSL---NGSIA----YRC-----MPGPRSSRTVLLHAAPQFIVKPKNTTA 4581
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G + C+A G P PT+ W+ +G +I Y V T+N T +
Sbjct: 4582 AIGAIVELRCSAAGPPHPTITWAKDGK--LIEDSKFEIAYSHLKV-------TLNST--S 4630
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAIC 423
DS C A N GSS V + V ++ P P SNQ K++AV C
Sbjct: 4631 DS-GEYTCMAQNSVGSSTVSAFINV-DNNILPTP---KPSSNQ----KNVAVITCYERNQ 4681
Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKD---LDKSDSGTYTCVASSR 472
+ W + G + +N + N+G+LV+ D L + D YTC +R
Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734
Score = 88.2 bits (209), Expect = 3e-17
Identities = 88/309 (28%), Positives = 130/309 (42%), Gaps = 26/309 (8%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I +P + T A L C A G P P I W K G L + D+ I + L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKL-IEDSKFEIAYSHLKVTLN 4627
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
+T SD+G Y C A NS G ++T+ + + L S Q + V+ C
Sbjct: 4628 ST-----SDSGEYTCMAQNSVG-----SSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA---RQTDAGRYQCIARNAAG 187
+ + W+ NG + + +H ++ G+LVI D ++ D Y C RN
Sbjct: 4678 ERNQAYSRGLTWEYNGVPMP-KNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRN--- 4733
Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPL-PDVLWRRSAGGGNM 244
R +I L + P + T + V G SV C V DPL V+W ++ +
Sbjct: 4734 RRRHSIPHLTSAFEGVPEVKT-IDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN-DQKML 4791
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSPNS 301
+ VL + SL L NV DEG Y C A NS+G L VY+ P +
Sbjct: 4792 DDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSG 4851
Query: 302 VNVESGNVA 310
+N++ + A
Sbjct: 4852 INIDDSSNA 4860
Score = 82.2 bits (194), Expect = 2e-15
Identities = 109/467 (23%), Positives = 178/467 (38%), Gaps = 52/467 (11%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P ++ + ++V+ Q L+C A G P P I W + + + + + + L A
Sbjct: 4410 PEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTL----A 4465
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ D G Y C A + G + AT + V + R P + +EC
Sbjct: 4466 IRNVLPDDDGFYHCIAKSDAG---QKIATRKLIVNKPSDRPAP----------IWVEC-D 4511
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
+G P+ Y G T D L+ + ++D+ + Y+C+ G R S
Sbjct: 4512 EKGKPKKTEYMIDRGDT----PDDNPQLLPWKD--VEDSSLNGSIAYRCMP----GPRSS 4561
Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
T+ +H P I P++ A G+ V +C G P P + W A G +
Sbjct: 4562 R--TVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITW---AKDGKLIEDSKFE 4616
Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
+ L++ +D GEY+C A+NSVG+ + S ++ V + P+S NVA
Sbjct: 4617 IAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSS---NQKNVAV 4673
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD--KNDSRNT 369
TC + + T + G+ K A F L I DT K
Sbjct: 4674 ITCYERNQ-------AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLEL 4726
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP-EPI 428
C N S +TS + P + T + V C P
Sbjct: 4727 YTCKVRNRRRHSIPH----LTSAFEGVPEVKT--IDKVEVNNGDSVVLDCEVTSDPLTTH 4780
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W + ++ + V + +LVL +++K D G Y CVAS+ GK
Sbjct: 4781 VVWTKNDQKMLDDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGK 4827
Score = 77.8 bits (183), Expect = 4e-14
Identities = 79/334 (23%), Positives = 134/334 (40%), Gaps = 20/334 (5%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
D ++ + AP + T+ R + TL+C I W K G+ + + L
Sbjct: 1817 DFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ-ITWMKQGLPLTENDAIFTL 1875
Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L L A R H D +Y C A N+ G S++ + V VL + + + + +
Sbjct: 1876 DNTRLTILNAN--RDHED--IYTCVANNTAGQV-SKDFDVVVQVL-PKIKNAVVTLEINE 1929
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ ++L C G+P P W N L + + + + +V+ + + G Y+C
Sbjct: 1930 GEEIILTC-DAEGNPTPTAKWDFNQGDLPKEA---VFVNNNHTVVVNNVTKYHTGVYKCY 1985
Query: 182 ARNAAGTRESAIATLKIHI--KPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
A N G A+ T+ +H+ KP +G ++ S+T +C V + W
Sbjct: 1986 ATNKVG---QAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042
Query: 238 SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ V+ L G L + + D G Y+C N G + + L V PP+I
Sbjct: 2043 NGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
V N C TG+P P + W+ +G
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG 2136
Score = 76.6 bits (180), Expect = 1e-13
Identities = 120/515 (23%), Positives = 196/515 (38%), Gaps = 46/515 (8%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
+ TL C G P P I W G +V ++ + L V + G Y C
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQE-GNYHC 1623
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKK 144
A + + + ++VL E ++ + G + L C L + W
Sbjct: 1624 VAQSK---GNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSI 1680
Query: 145 NGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
NG D + + DG L I DA+ + G+Y C N+AG E + TL + ++P
Sbjct: 1681 NGSE--SDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTL-TLDV-LEPP 1736
Query: 204 LITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRL 259
+ P Q + + QC+V G+P P V+W+ GN + + + D+ SL
Sbjct: 1737 VFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKID---GN-DVDKSWLFDESLSLLR 1792
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV--ESGNVARFTCTAT 317
+ + SC AEN G S ++ P+ + + ES + +
Sbjct: 1793 IEKLTGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSL 1852
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G + T W +G P D A D T LTI + ++ D + C A N
Sbjct: 1853 GDFQIT--WMKQG-----LPLTEND---AIFTLDN-TRLTILNANR-DHEDIYTCVANNT 1900
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
AG + V + P I N + + C A P P W F +
Sbjct: 1901 AGQVSKDFDVVV-----QVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDF-NQG 1954
Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
+ V N+ T+V+ ++ K +G Y C A+++ G+ V + ++ + F
Sbjct: 1955 DLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKT----INVHVRTKPRFESG 2010
Query: 498 ADVSSLPGPPTKPIT--HNVTDT-SVTLSWSQNNK 529
S L T+ IT +V D V +SW+ N K
Sbjct: 2011 LTESELTVNLTRSITLECDVDDAIGVGISWTVNGK 2045
>Z47070-7|CAA87344.1| 5175|Caenorhabditis elegans Hypothetical protein
F15G9.4a protein.
Length = 5175
Score = 161 bits (391), Expect = 3e-39
Identities = 145/510 (28%), Positives = 222/510 (43%), Gaps = 30/510 (5%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA +QP + C G P P+I+W K G V D + I+ G + + T AG
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDS---DHAGK 3835
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
+ C A N G + L V ++ ++ A G+T+ L C G+P P + W
Sbjct: 3836 WSCVAENDAGV-KELEMVLDVFT-PPVVSVKSDNPIKALGETITLFC-NASGNPYPQLKW 3892
Query: 143 KKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
K G +L+FD D + G L I ++TD G Y C A NAAGT E+++ ++ + +
Sbjct: 3893 AKGG-SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASV-SVDVLVP 3950
Query: 202 PYLITGPEDVVAQ--TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LR 258
P + D+ + S+T QC G P+P + W + + V D + ++
Sbjct: 3951 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 4010
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
++NV L+D+G Y+C AEN G+ + + V P I+ + + V G +A C G
Sbjct: 4011 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS-NGGTKQVIEGELAVIECLVEG 4069
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
P P + W GNR + G+ +Y V DG +LTI + DS +CSA N A
Sbjct: 4070 YPAPQVSWLRNGNR--VETGVQGVRY----VTDG-RMLTIIEARSLDS-GIYLCSATNEA 4121
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
GS+ L V P IIT+ P T S PC P+PII+W G +
Sbjct: 4122 GSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDI 4177
Query: 439 IQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
+ DGTL ++ ++ Y C A + G V + + P I
Sbjct: 4178 KDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLE--FPVQTIVAPKISTSGN 4234
Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
++ G T I + S SWS+N
Sbjct: 4235 RYINGSEGTET-VIKCEIESESSEFSWSKN 4263
Score = 151 bits (367), Expect = 2e-36
Identities = 123/446 (27%), Positives = 189/446 (42%), Gaps = 29/446 (6%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C G+P P I WY G + ++ + A +R S +GVY C+ATNS G
Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKAD---KSYSGVYTCQATNSAG 1078
Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
+ + ++ +S + D + G P+P + W LL D
Sbjct: 1079 DNEQKTT---IRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITW------LLDD 1129
Query: 153 GDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211
+V + G+L I + + G + C A+NAAG ++ TL +H P + ++
Sbjct: 1130 KPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAG-NDTRTVTLTVHTTPTINAENQEK 1188
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
+A + +C P P LW + L + +DG+L L NV L + G +
Sbjct: 1189 IALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFV 1248
Query: 272 CEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
C+ N G S S LTV++ P I+ P V+V G C ATG PE W+ G
Sbjct: 1249 CQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNG 1308
Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
I M K+ D + L I + DKND N C N AG+S ++T
Sbjct: 1309 ----IDLKMDEKKFSV----DNLGTLRIYEADKNDIGN-YNCVVTNEAGTS----QMTTH 1355
Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-ND 449
D PP I+ + +N T + C +P + W+ G A+ + + V +D
Sbjct: 1356 VDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESD 1415
Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGK 475
GTLV++ D+ YTC AS+ GK
Sbjct: 1416 GTLVIQSASVEDATIYTCKASNPAGK 1441
Score = 141 bits (342), Expect = 2e-33
Identities = 130/510 (25%), Positives = 225/510 (44%), Gaps = 45/510 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
++C+ G P P + W + G + I + +R +D G Y C A+N
Sbjct: 3236 VHCQVTGRPVPYVTWKRNG--------KEIEQFNPVLHIR---NATRADEGKYSCIASNE 3284
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
GTA + L + F + +G++ +EC G P+P + W K G+
Sbjct: 3285 AGTAVAD--FLIDVFTKPTFETHETTFNIVEGESAKIECKID-GHPKPTISWLKGGRP-- 3339
Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-TGPE 209
F+ D+ + G L+I A++ D G Y C+A N+ G E + ++ KPY+ T +
Sbjct: 3340 FNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFK-VNVYTKPYIDETIDQ 3398
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEG 268
A G + +C V G+P P V W+R G +P R ++++ L++++V D G
Sbjct: 3399 TPKAVAGGEIILKCPVLGNPTPTVTWKR--GDDAVPNDSRHTIVNNYDLKINSVTTEDAG 3456
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
+YSC A N G ++ V P+ + N V + C T RP P++ W
Sbjct: 3457 QYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISW- 3515
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
G++ + D+Y + DG + +TIN +D +C A N AG+S + L
Sbjct: 3516 FRGDKPVYL----YDRYSISP--DG-SHITINKAKLSDG-GKYICRASNEAGTSDIDLIL 3567
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVF-PCTAICTPEPIIAWYFEGEALIQNHRRNV 446
+ PP I + L I + ++ C P+P + W G + R +
Sbjct: 3568 KILV----PPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVI 3623
Query: 447 T--NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH-----FFRAAD 499
N+ T ++++ +D G YTC A++R GK +L V SP +IH R D
Sbjct: 3624 LAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGD 3683
Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+L P + ++ D + +SW+++++
Sbjct: 3684 TITLTCP--IKLAEDIADQVMDVSWTKDSR 3711
Score = 138 bits (334), Expect = 2e-32
Identities = 122/451 (27%), Positives = 185/451 (41%), Gaps = 31/451 (6%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
Q TL C A G P P +RW G + T I A F++ + + SD GVY C
Sbjct: 3968 QSLTLQCLAQGKPVPQMRWTLNGTALTHSTP-GITVASDSTFIQINNVSL-SDKGVYTCY 4025
Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
A N G S N +V V++ +KQ +G+ V+ECL G P P V W +NG
Sbjct: 4026 AENVAG---SDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLV-EGYPAPQVSWLRNG 4081
Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
+ ++ DG L I +AR D+G Y C A N AG+ + A TL++ + P +IT
Sbjct: 4082 NRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAY-TLEVLVSPKIIT 4140
Query: 207 G-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
P + +GS + C V G P P + W + + DG+L ++ A
Sbjct: 4141 STPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEK---A 4197
Query: 266 DEGE--YSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVESGNVARFTCTATGRPEP 322
+E Y C A+N GA + + P I+ S N +N G C
Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESE-SS 4256
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
WS G P + + + + + +L+ +D+ + C+A N AG++
Sbjct: 4257 EFSWSKNG-----VPLLPSNNLIFSEDYKLIKILSTRLSDQGE----YSCTAANKAGNAT 4307
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN- 441
+ L V P I P Q + C A P+P I WY + E L
Sbjct: 4308 QKTNLNV-----GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTG 4362
Query: 442 -HRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
T +++ + S +G YTC A +
Sbjct: 4363 VDETATTKKKSVIFSSISPSQAGVYTCKAEN 4393
Score = 137 bits (331), Expect = 5e-32
Identities = 121/463 (26%), Positives = 195/463 (42%), Gaps = 28/463 (6%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + C G P+P + W + G V + G L R D+G+Y C AT
Sbjct: 4061 AVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM-LTIIEAR-SLDSGIYLCSAT 4118
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
N G+A+ TL V V + P + G L C RG P+P + W NG
Sbjct: 4119 NEAGSAQQAY-TLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV-RGYPDPIISWTLNGND 4176
Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYLIT 206
+ DG++ + G L I+ A + Y+C A+N AG T E + T+ + P + T
Sbjct: 4177 IK-DGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTI---VAPKIST 4231
Query: 207 -GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVIL 264
G + G+ +C + + + W ++ G +P + +D L ++ + L
Sbjct: 4232 SGNRYINGSEGTETVIKCEIESES-SEFSWSKN-GVPLLPSNNLIFSEDYKLIKILSTRL 4289
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
+D+GEYSC A N G + L V P I P + V G+ C A+G P+P +
Sbjct: 4290 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAI 4349
Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
W + N + G+ AT V +I+ + C A N+ S+
Sbjct: 4350 TW-YKDNELLTNTGVDET---ATTKKKSVIFSSISPSQAG----VYTCKAENWVASTEED 4401
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
L V PP ++ + T P + C A PEP+I+W + IQN+ +
Sbjct: 4402 IDLIVMI----PPEVVPERMNVSTNP-RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEK 4456
Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
TL ++++ D G Y C+A S G+ + + L+V+ P
Sbjct: 4457 YQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP 4499
Score = 136 bits (329), Expect = 9e-32
Identities = 126/472 (26%), Positives = 200/472 (42%), Gaps = 23/472 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V + E+P I +V+V + A L+C + IRW + G V + + P G
Sbjct: 514 VETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNG 573
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+ H +DAGVY C A N+ G + +R L + + ++ P+ + V
Sbjct: 574 TLKI---HHVTRADAGVYECMARNAGGMS-TRKMRLDI-MEPPSVKVTPQDVYFNMREGV 628
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C G P+P V+W G+ LL D ++ D L I+DA D G Y+C A +
Sbjct: 629 NLSC-EAMGDPKPEVHWYFKGRHLLNDYKYQVGQ-DSKFLYIRDATHHDEGTYECRAMSQ 686
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWRRSAGGGNM 244
AG L + P + ++ G V+F+C+ + G P P + W ++
Sbjct: 687 AGQARDT-TDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIK 745
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
P +K+ ++G L + D G YSC EN G L+V P+I SP++V V
Sbjct: 746 PDDYIKI-NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRV 804
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
C A G P P + W +GN ++ ++ +Y T + DG L I D
Sbjct: 805 NIERQVTLQCLAVGIPPPEIEWQ-KGN--VLLATLNNPRY--TQLADG--NLLITDAQIE 857
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC- 423
D + C A N G L VT P++ + P + L C +
Sbjct: 858 D-QGQFTCIARNTYGQQSQSTTLMVTG---LVSPVLGHVPPEEQLIEGQDLTLSCVVVLG 913
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474
TP+P I W + + + + + G+L+ L+ + D G YTC+A S G
Sbjct: 914 TPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAG 965
Score = 135 bits (327), Expect = 2e-31
Identities = 129/474 (27%), Positives = 202/474 (42%), Gaps = 28/474 (5%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
++++ + T H TL+C A G P P I W+K G + + I+P G L +
Sbjct: 2291 MLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKI 2350
Query: 74 GRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
R+ DAG Y CEA NS G+ + + + E P +S Q + VV+ C P
Sbjct: 2351 TRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC-PV 2409
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT--RE 190
P + W K G+ L D + +G L + R+TD+ +Y CIA N AGT R+
Sbjct: 2410 YARPPAKITWLKAGKPLQSDKFVKTS-ANGQKLYLFKLRETDSSKYTCIATNEAGTDKRD 2468
Query: 191 SAIATL--KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
++ L +P ++ + +G+ T C G P P + W + G P R
Sbjct: 2469 FKVSMLVAPSFDEPNIV---RRITVNSGNPSTLHCPAKGSPSPTITWLKD-GNAIEPNDR 2524
Query: 249 VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSPNSVNVES 306
D G L++ +D+G Y+C A NSVG+ L V PP I+ +V V
Sbjct: 2525 YVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIE 2584
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G + C + + W +G TI + D + + ++ K+DS
Sbjct: 2585 GFSSELFCDSNS-TGVDVEWQKDG-LTINQDTLRGDSF--IQIPSSGKKMSFLSARKSDS 2640
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN---QTLPIKSMAVFPCTAIC 423
C N AG + KL + +D PP I++ S+ QT+ C
Sbjct: 2641 -GRYTCIVRNPAGEA---RKLFDFAVND--PPSISDELSSANIQTIVPYYPVEINCVVSG 2694
Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
+P P + W F+ + L + +TN+G TL + +GTYTC A + GK
Sbjct: 2695 SPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGK 2748
Score = 134 bits (323), Expect = 5e-31
Identities = 135/505 (26%), Positives = 215/505 (42%), Gaps = 57/505 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGL 66
G P IIE P V V + TL C A G P P I W KG VL+ +++ + L G L
Sbjct: 790 GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGNL 849
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTV 125
T ++ D G + C A N+YG +S++ TL V ++ P +Q +G +
Sbjct: 850 LI---TDAQI-EDQGQFTCIARNTYG-QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDL 904
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184
L C+ G+P+P++ W K+ + + + + + GG+L+ ++ D G+Y CIA +
Sbjct: 905 TLSCVVVLGTPKPSIVWIKDDKPV--EEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVS 962
Query: 185 AAGTRESAIATLKIHIKPYLITGPED-----------------VVAQT-----GSSVTFQ 222
AG I +++ KP + PE VV T G
Sbjct: 963 PAGNSTLHI-NVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
C V G P P + W G P R V D +L + + G Y+C+A NS G
Sbjct: 1022 CVVSGTPPPIITWYLD-GRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDN 1080
Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
+ + + P I+ +S N+ ++ C G P+P + W ++
Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD------------ 1128
Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
DK V + LTI + ++ R T C A N AG+ TVT P I
Sbjct: 1129 DKPFTEGVVNEDGSLTIPNVNE-AHRGTFTCHAQNAAGND----TRTVTLTVHTTPTI-- 1181
Query: 402 NGPSNQTLPIKS-MAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDK 459
N + + + +++ V C A P P+ W +EGE + Q + DG LVL+++
Sbjct: 1182 NAENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKL 1241
Query: 460 SDSGTYTCVASSRHGKYVWSGALLV 484
++G + C S+ G+ S L V
Sbjct: 1242 ENTGVFVCQVSNLAGEDSLSYTLTV 1266
Score = 133 bits (322), Expect = 6e-31
Identities = 139/501 (27%), Positives = 212/501 (42%), Gaps = 65/501 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT +P + P + + Q TL+C G+P P+I W K V I G
Sbjct: 881 VTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGG 940
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL---REEFRLEPES----- 116
L LR + + D G Y C A + G N+TLH+ V + EF +PE
Sbjct: 941 SLLRLRGGNPK---DEGKYTCIAVSPAG-----NSTLHINVQLIKKPEFVYKPEGGIVFK 992
Query: 117 --------KQSA---------QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
K A G+ + C+ G+P P + W +G+ + +SR
Sbjct: 993 PTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVS-GTPPPIITWYLDGRPIT--PNSRDFT 1049
Query: 160 VDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
V N L+++ A ++ +G Y C A N+AG E T++I P + G
Sbjct: 1050 VTADNTLIVRKADKSYSGVYTCQATNSAGDNEQK-TTIRIMNTPMISPGQSSFNMVVDDL 1108
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
T C V GDP P + W + P V +DGSL + NV A G ++C A+N+
Sbjct: 1109 FTIPCDVYGDPKPVITWLLD----DKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAA 1164
Query: 279 GAVSASGYLTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR--TII 335
G + + LTV+ P+IN + + +++ ++ C A P P W+ EG + + +
Sbjct: 1165 GNDTRTVTLTVHTTPTINAENQEKIALQNDDIV-LECPAKALPPPVRLWTYEGEKIDSQL 1223
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
P R+ DG VL K ++ VC N AG + LTV
Sbjct: 1224 IPHTIRE--------DGALVL---QNVKLENTGVFVCQVSNLAGEDSLSYTLTV----HE 1268
Query: 396 PPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLV 453
P II+ P + +K + PC A PE I W G L + ++ +V N GTL
Sbjct: 1269 KPKIISEVPGVVDV-VKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR 1327
Query: 454 LKDLDKSDSGTYTCVASSRHG 474
+ + DK+D G Y CV ++ G
Sbjct: 1328 IYEADKNDIGNYNCVVTNEAG 1348
Score = 133 bits (321), Expect = 8e-31
Identities = 129/477 (27%), Positives = 195/477 (40%), Gaps = 40/477 (8%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D YV E P ++ + V + T+ C G+P P + W K G SD +
Sbjct: 3118 DTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTK 3177
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSA 120
L LR T +D G Y C ATN G +++ T V VL R+E E + Q
Sbjct: 3178 LSYL-HLRET---TLADGGTYTCIATNKAGESQT---TTDVEVLVPP-RIEDEERVLQGK 3229
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+G+T ++ C G P P V WK+NG+ + + + V L I++A + D G+Y C
Sbjct: 3230 EGNTYMVHC-QVTGRPVPYVTWKRNGKEI-----EQFNPV----LHIRNATRADEGKYSC 3279
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
IA N AGT A + + KP T G S +C++ G P P + W + G
Sbjct: 3280 IASNEAGT-AVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLK--G 3336
Query: 241 GGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS- 298
G + + + G +L + D G Y+C A NS G + VY P I+ +
Sbjct: 3337 GRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETI 3396
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ +G C G P PT+ W G+ + P SR + +D L I
Sbjct: 3397 DQTPKAVAGGEIILKCPVLGNPTPTVTWK-RGDDAV--PNDSR--HTIVNNYD----LKI 3447
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N D+ C AVN AG+ V P + G + +
Sbjct: 3448 NSVTTEDA-GQYSCIAVNEAGNLTTHYAAEVIG----KPTFVRKGGNLYEVIENDTITMD 3502
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474
C P P I+W+ + + R +++ DG+ + + SD G Y C AS+ G
Sbjct: 3503 CGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAG 3559
Score = 128 bits (310), Expect = 2e-29
Identities = 129/484 (26%), Positives = 191/484 (39%), Gaps = 35/484 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
V + T++C P P+I W++G V SI P G + SD G
Sbjct: 3493 VIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAK---LSDGGK 3549
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVY 141
Y C A+N GT+ + L + V + + A T+ LEC P G P+P+V
Sbjct: 3550 YICRASNEAGTS-DIDLILKILVPPKIDKSNIIGNPLAIVARTIYLEC-PISGIPQPDVI 3607
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
W KNG + DSR+ L I++ + TD GRY C A N G + +
Sbjct: 3608 WTKNGMDINMT-DSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSP 3666
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVG-----GDPLPDVLWRRSAGGGNMPL-GRVKVLDD 254
+ I G + + + G ++T C + D + DV W + + + L V + DD
Sbjct: 3667 PEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDD 3726
Query: 255 G-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVAR 311
G L + L + G Y+C A N G S + + PP I++S N V V
Sbjct: 3727 GRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTI 3786
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
C TG P P++ W G D + V G VL I TD +D
Sbjct: 3787 MRCAVTGHPFPSIKWLKNGKEV-------TDDENIRIVEQG-QVLQILRTD-SDHAGKWS 3837
Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
C A N AG + L V + PP+++ N + C A P P + W
Sbjct: 3838 CVAENDAGVKELEMVLDVFT-----PPVVSVKSDNPIKALGETITLFCNASGNPYPQLKW 3892
Query: 432 YFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
G + + R L + L K+D G YTC A + G ++ VD +
Sbjct: 3893 AKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAG--TSEASVSVDVLVP 3950
Query: 490 PNIH 493
P I+
Sbjct: 3951 PEIN 3954
Score = 124 bits (299), Expect = 4e-28
Identities = 109/455 (23%), Positives = 187/455 (41%), Gaps = 20/455 (4%)
Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
T+ + P +NC GSP P + W + D+ L G L+ +V AG
Sbjct: 2679 TIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET-LKIVRSQVEH-AG 2736
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
Y CEA N+ G AR ++ + V F E E + GDT++L C P +VY
Sbjct: 2737 TYTCEAQNNVGKAR-KDFLVRVTA-PPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVY 2794
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W + +++ + + + L + + + D G Y C A N AG + + I
Sbjct: 2795 WHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIE-T 2853
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
PY + + G +T C G P P +L+ + N V ++ +L +DN
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLN-ESDEVDII-GSTLVIDN 2911
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
EG Y+C AEN G + V PP ++ +V V++G+ C
Sbjct: 2912 PQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSG 2971
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
+ WS + + ++ + ++ + T D D + C AVN AG +
Sbjct: 2972 VHITWSRQFGKDGQLDMRAQSSSDKSKLY--IMQATPEDAD------SYSCIAVNDAGGA 3023
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
++TV + PP I + S + + PC P P I+W+ +G+ +++
Sbjct: 3024 EAVFQVTVNT----PPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEM 3079
Query: 442 HRRNV-TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
D +L + ++ + G YTCVA ++ G+
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGR 3114
Score = 123 bits (297), Expect = 7e-28
Identities = 115/417 (27%), Positives = 170/417 (40%), Gaps = 27/417 (6%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
DAG Y C ++ G + E F + S G+ L C R + E
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPL--GEAAFLHC-STRSAGEV 549
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
+ W + G T+ F+G + G L I + DAG Y+C+ARNA G + L I
Sbjct: 550 EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMR-LDI 607
Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257
P + P+DV V C GDP P+V W G + + +V D L
Sbjct: 608 MEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFK-GRHLLNDYKYQVGQDSKFL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TA 316
+ + DEG Y C A + G + L + PP + + N + V G+ F C T
Sbjct: 667 YIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTI 726
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G+P P + W G + +I P D Y + +G L I K++ C N
Sbjct: 727 RGKPHPKIRWFKNG-KDLIKP----DDY--IKINEGQ--LHIMGA-KDEDAGAYSCVGEN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG L+V R P II + P + I+ C A+ P P I W +G
Sbjct: 777 MAGKDVQVANLSV----GRVPTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGN 830
Query: 437 ALI---QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
L+ N R DG L++ D D G +TC+A + +G+ S L+V ++P
Sbjct: 831 VLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP 887
Score = 121 bits (292), Expect = 3e-27
Identities = 109/470 (23%), Positives = 184/470 (39%), Gaps = 32/470 (6%)
Query: 6 VTSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT P I T + + CR G P P I W+ G ++ +
Sbjct: 3029 VTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMP--GVTYKQ 3086
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G LR + + + + G Y C A N G A ++ + ++ + E + +G
Sbjct: 3087 GDLSLRIDNIKPNQE-GRYTCVAENKAGRAE-QDTYVEISE-PPRVVMASEVMRVVEGRQ 3143
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ C G+PEP V W K+G+ + D L +++ D G Y CIA N
Sbjct: 3144 TTIRC-EVFGNPEPVVNWLKDGEP--YTSDLLQFSTKLSYLHLRETTLADGGTYTCIATN 3200
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG ++ +++ + P + + + G++ C+V G P+P V W+R+
Sbjct: 3201 KAGESQTT-TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN------ 3253
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
G+ + L + N ADEG+YSC A N G A + V+ P+ + N+
Sbjct: 3254 --GKEIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNI 3311
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G A+ C G P+PT+ W ++G R + D + D + +L D
Sbjct: 3312 VEGESAKIECKIDGHPKPTISW-LKGGRP-----FNMDNIILSPRGDTLMILKAQRFD-- 3363
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
C A N G S K+ V + P I + C +
Sbjct: 3364 --GGLYTCVATNSYGDSEQDFKVNVYT----KPYIDETIDQTPKAVAGGEIILKCPVLGN 3417
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P + W +A+ + R + N+ L + + D+G Y+C+A + G
Sbjct: 3418 PTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEAG 3467
Score = 120 bits (288), Expect = 8e-27
Identities = 121/466 (25%), Positives = 184/466 (39%), Gaps = 32/466 (6%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
T+ C G P P I W +L ++ G + + + G + C A N
Sbjct: 1110 TIPCDVYGDPKPVITW----LLDDKPFTEGVVNEDGSLTIPNVN---EAHRGTFTCHAQN 1162
Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
+ G +R TL V E + K + Q D +VLEC P + P P W G+ +
Sbjct: 1163 AAGND-TRTVTLTVHTT-PTINAENQEKIALQNDDIVLEC-PAKALPPPVRLWTYEGEKI 1219
Query: 150 LFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
D H + + G LV+Q+ + + G + C N AG +S TL +H KP +I+
Sbjct: 1220 --DSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAG-EDSLSYTLTVHEKPKIISEV 1276
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
VV G ++ CR G P W ++ M + V + G+LR+ D
Sbjct: 1277 PGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLRIYEADKNDI 1336
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTCTATGRPEPTMFW 326
G Y+C N G + ++ V +PP I S + N G+ C P ++ W
Sbjct: 1337 GNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTW 1396
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
G I G Y V + L I D+ C A N AG + +
Sbjct: 1397 FRRG----IAIGTDTKGY----VVESDGTLVIQSASVEDA-TIYTCKASNPAGKAEANLQ 1447
Query: 387 LTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445
+TV S D + P ++T ++ P C P P I+WY + LI +
Sbjct: 1448 VTVIASPDIKDPDVVTQESIKESHPFS----LYCPVFSNPLPQISWYLNDKPLIDDKTSW 1503
Query: 446 VTNDGTLVLKDLDK--SDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
T+D L +DSG Y CVA + G+ S + V P+N
Sbjct: 1504 KTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLN 1549
Score = 120 bits (288), Expect = 8e-27
Identities = 121/472 (25%), Positives = 188/472 (39%), Gaps = 38/472 (8%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E PY ++Q + + TL+C A G+P P I + K G + I+ G +
Sbjct: 2852 ETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--GSTLVI 2909
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
V G Y C A N G RS + +L + E + + GD + LEC
Sbjct: 2910 DNPQKEVE---GRYTCIAENKAG--RSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLEC 2964
Query: 130 LPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
P + ++ W + G+ D ++ D L I A DA Y CIA N AG
Sbjct: 2965 -PIEDTSGVHITWSRQFGKDGQLDMRAQSSS-DKSKLYIMQATPEDADSYSCIAVNDAGG 3022
Query: 189 RESAIATLKIHIKPYLIT---GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
E A+ + ++ P + ++VA T ++ CR G P P++ W
Sbjct: 3023 AE-AVFQVTVNTPPKIFGDSFSTTEIVADT--TLEIPCRTEGIPPPEISWFLDGKPILEM 3079
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
G D SLR+DN+ EG Y+C AEN G Y+ + +PP + ++ + V
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVV 3139
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G C G PEP + W +G P S +T ++ L + +T D
Sbjct: 3140 EGRQTTIRCEVFGNPEPVVNWLKDGE-----PYTSDLLQFSTK----LSYLHLRETTLAD 3190
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
T C A N AG S T T + PP I + + + C P
Sbjct: 3191 G-GTYTCIATNKAGES-----QTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244
Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
P + W G+ + Q + L +++ ++D G Y+C+AS+ G V
Sbjct: 3245 VPYVTWKRNGKEIEQ-------FNPVLHIRNATRADEGKYSCIASNEAGTAV 3289
Score = 118 bits (285), Expect = 2e-26
Identities = 128/483 (26%), Positives = 203/483 (42%), Gaps = 61/483 (12%)
Query: 23 VARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V R + C+ G P P IRW+K G ++ + G L + G DAG
Sbjct: 713 VGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIM----GAKDEDAG 768
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNV 140
Y C N G +++V R +E P + + V L+CL G P P +
Sbjct: 769 AYSCVGENMAGKDVQ---VANLSVGRVPTIIESPHTVRVNIERQVTLQCLAV-GIPPPEI 824
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH- 199
W+K L + R + GNL+I DA+ D G++ CIARN G ++S TL +
Sbjct: 825 EWQKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYG-QQSQSTTLMVTG 883
Query: 200 -IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGR---VKVLDD 254
+ P L P + G +T C V G P P ++W + + P+ +K+
Sbjct: 884 LVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKD----DKPVEEGPTIKIEGG 939
Query: 255 GS-LRLDNVILADEGEYSCEAENSVG--AVSASGYLT-----VYDPP-SINLSPNSVNVE 305
GS LRL DEG+Y+C A + G + + L VY P I P ++
Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999
Query: 306 SGNVA--------------RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
+VA C +G P P + W ++G I P SRD + TA
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRP--ITPN-SRD-FTVTA--- 1052
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L + DK+ S C A N AG + + + + + P+I+ G S+ + +
Sbjct: 1053 -DNTLIVRKADKSYS-GVYTCQATNSAGDNEQKTTIRIMN-----TPMISPGQSSFNMVV 1105
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
+ PC P+P+I W + + + V DG+L + +++++ GT+TC A +
Sbjct: 1106 DDLFTIPCDVYGDPKPVITWLLDDKPFTEG---VVNEDGSLTIPNVNEAHRGTFTCHAQN 1162
Query: 472 RHG 474
G
Sbjct: 1163 AAG 1165
Score = 116 bits (278), Expect = 1e-25
Identities = 125/466 (26%), Positives = 191/466 (40%), Gaps = 28/466 (6%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++TV + TL C + I W G +++T AGG F L + D
Sbjct: 2015 ELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGVQTLAGGRF-LHIVSAKT-DD 2072
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
G Y C TN G A ++ L V V E + +++VL C G P P
Sbjct: 2073 HGSYACTVTNEAGVA-TKTFNLFVQVPPTIVN-EGGEYTVIENNSLVLPC-EVTGKPNPV 2129
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
V W K+G+ + D S L +G I A G Y C+A+N GT E + + I
Sbjct: 2130 VTWTKDGRPV-GDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEISF-DVDII 2187
Query: 200 IKPYLITGPEDVV-AQTGSSVTFQCRVGGDP--LPDVLWRRSAGGGNMPLGRVKVL---D 253
+P + G +++V A G ++ F+C + D ++W R+ ++ ++ +
Sbjct: 2188 TRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSN 2247
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVA 310
D L + NV DEG+YSC +N G S TV PP+I + N VE V
Sbjct: 2248 DRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVT 2307
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
+C ATG+PEP + W +G I ++ + + + + I + D
Sbjct: 2308 -LSCPATGKPEPDITWFKDG-EAIHIENIADIIPNGELNGNQLKITRIKEGD----AGKY 2361
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AGS + V + P I +G PS+ V C P I
Sbjct: 2362 TCEADNSAGSVEQDVNVNVIT----IPKIEKDGIPSDYESQQNERVVISCPVYARPPAKI 2417
Query: 430 AWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
W G+ L + N L L L ++DS YTC+A++ G
Sbjct: 2418 TWLKAGKPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAG 2463
Score = 110 bits (264), Expect = 7e-24
Identities = 114/460 (24%), Positives = 188/460 (40%), Gaps = 45/460 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C SP ++ W++ G+ + +DT ++ + G +++ DA +Y C+A+N
Sbjct: 1382 LKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE---DATIYTCKASNP 1438
Query: 91 YGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
G A A L V V+ +P+ + + L C P +P P + W N +
Sbjct: 1439 AGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYC-PVFSNPLPQISWYLNDK 1494
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT-----RESAIATLKIHIKP 202
L+ D S D L + A+ TD+G Y+C+ARNAAG + I L +
Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESK 1554
Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSLRL 259
Y + V A+ G VT C V G P+P + W G G D +L
Sbjct: 1555 Y----KKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHF 1610
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TATG 318
D+V + EG Y C A++ + L+V P + N + V G +C T
Sbjct: 1611 DSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDN-LEVFLGKDISLSCDLQTE 1669
Query: 319 RPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
+ T F WS+ G+ + D+ + L I D K ++ +C N
Sbjct: 1670 SDDKTTFVWSINGSES--------DRPDNVQIPSDGHRLYITDA-KPENNGKYMCRVTNS 1720
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + + T+T D PP + +NQ L + + C P+P + W +G
Sbjct: 1721 AG----KAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGN 1776
Query: 437 ALIQNHRRNVTNDGTLVLKDLDK--SDSGTYTCVASSRHG 474
+ ++ D +L L ++K S +C A ++ G
Sbjct: 1777 DV----DKSWLFDESLSLLRIEKLTGKSAQISCTAENKAG 1812
Score = 104 bits (249), Expect = 4e-22
Identities = 98/387 (25%), Positives = 144/387 (37%), Gaps = 20/387 (5%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I P +T + +L C G P P I W G + + + A G +
Sbjct: 4139 ITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAE 4198
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R H +Y C A N G A + + V + ++G V++C
Sbjct: 4199 ER-HL---IYECTAKNDAG-ADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES 4253
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
S E + W KNG LL ++ + D + I R +D G Y C A N AG
Sbjct: 4254 ESSEFS--WSKNGVPLL-PSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQK- 4309
Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVL 252
L + + P ++ P V G VT C G P P + W + N +
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT 4369
Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
S+ ++ + G Y+C+AEN V + L V PP + +V+
Sbjct: 4370 KKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFL 4429
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
+C ATG PEP + W + N I + +KY T L I + +D C
Sbjct: 4430 SCNATGIPEPVISWMRDSNIAI----QNNEKYQILG-----TTLAIRNVLPDDD-GFYHC 4479
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPI 399
A + AG KL V DRP PI
Sbjct: 4480 IAKSDAGQKIATRKLIVNKPSDRPAPI 4506
Score = 98.3 bits (234), Expect = 3e-20
Identities = 109/363 (30%), Positives = 152/363 (41%), Gaps = 31/363 (8%)
Query: 6 VTSGEAPYII-EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63
+T E P II E P V V + + CRA G P W K G+ L + + S+
Sbjct: 1264 LTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNL 1323
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQ 121
G L A +D G Y C TN GT++ T HV V L + +
Sbjct: 1324 GTLRIYEAD----KNDIGNYNCVVTNEAGTSQ---MTTHVDVQEPPIILPSTQTNNTAVV 1376
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQC 180
GD V L+C SP +V W + G + D++ ++V+ G LVIQ A DA Y C
Sbjct: 1377 GDRVELKCY-VEASPPASVTWFRRG--IAIGTDTKGYVVESDGTLVIQSASVEDATIYTC 1433
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ----TGSSVTFQCRVGGDPLPDVLWR 236
A N AG E A L++ + DVV Q + C V +PLP + W
Sbjct: 1434 KASNPAGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWY 1490
Query: 237 RSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
+ K DD L + + D G Y C A N+ G S S + V P ++
Sbjct: 1491 LNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNL 1550
Query: 296 NLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH-ATAVFDG 352
+ S V + G C +G P P + W V+G T++ PG KY AT DG
Sbjct: 1551 DESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDG--TVVEPG---KKYKGATLSNDG 1605
Query: 353 VTV 355
+T+
Sbjct: 1606 LTL 1608
Score = 97.5 bits (232), Expect = 5e-20
Identities = 87/342 (25%), Positives = 139/342 (40%), Gaps = 23/342 (6%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IARNAAGTRESAIATLK 197
+YW K G+ ++ G H D I + DAG Y+C I+ N + ++ + T +
Sbjct: 460 IYWVKTGEDII-GGPLFYHNTDTSVWTIPELSLKDAGEYECRVISNNGNYSVKTRVETRE 518
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR-SAGGGNMPLGRVKVLDDGS 256
P I G +V G + C ++ W R A N P + +G+
Sbjct: 519 ---SPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGP-NTERNPTNGT 574
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
L++ +V AD G Y C A N+ G + L + +PPS+ ++P V +C A
Sbjct: 575 LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEA 634
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G P+P + W +G ++ KY V L I D +D T C A++
Sbjct: 635 MGDPKPEVHWYFKGRHL-----LNDYKYQ---VGQDSKFLYIRDATHHD-EGTYECRAMS 685
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEG 435
AG + L + + PP + + + F C I P P I W+ G
Sbjct: 686 QAGQARDTTDLMLAT-----PPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNG 740
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
+ LI+ N+G L + D+G Y+CV + GK V
Sbjct: 741 KDLIKPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDV 782
Score = 93.5 bits (222), Expect = 8e-19
Identities = 106/471 (22%), Positives = 181/471 (38%), Gaps = 34/471 (7%)
Query: 10 EAPYIIEQPLDVT--VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
E P +E + + + P L C+ G+P P + W G +D +S L L
Sbjct: 1734 EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDG----NDVDKSWLFDESLS 1789
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVV 126
LR ++ + C A N GTA SR+ + + F+ E + + + +T+
Sbjct: 1790 LLRIE--KLTGKSAQISCTAENKAGTA-SRDFFIQ-NIAAPTFKNEGDQETIFRESETIT 1845
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L+C P + + W K G L + D+ + +D L I +A + Y C+A N A
Sbjct: 1846 LDC--PVSLGDFQITWMKQGLPLT-ENDA-IFTLDNTRLTILNANRDHEDIYTCVANNTA 1901
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G + S + + + P + + G + C G+P P W G++P
Sbjct: 1902 G-QVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKW--DFNQGDLPK 1958
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNV 304
V V ++ ++ ++NV G Y C A N VG + + V P L+ + + V
Sbjct: 1959 EAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTV 2018
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
C + W+V G P ++ + G L I K
Sbjct: 2019 NLTRSITLECDVDDAIGVGISWTVNGK-----PFLA--ETDGVQTLAGGRFLHIVSA-KT 2070
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D + C+ N AG + L V + PP I N T+ + V PC
Sbjct: 2071 DDHGSYACTVTNEAGVATKTFNLFV-----QVPPTIVNEGGEYTVIENNSLVLPCEVTGK 2125
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
P P++ W +G + V ++G + + + G+Y C+A + G
Sbjct: 2126 PNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVG 2176
Score = 92.7 bits (220), Expect = 1e-18
Identities = 114/453 (25%), Positives = 176/453 (38%), Gaps = 45/453 (9%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
S S W K GV ++ + L + +T SD G Y C A N G A ++
Sbjct: 4253 SESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTR---LSDQGEYSCTAANKAGNA-TQ 4308
Query: 98 NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
L+V V + P ++ +GD V L C G P+P + W K+ + L G
Sbjct: 4309 KTNLNVGVAPKIME-RPRTQVVHKGDQVTLWC-EASGVPQPAITWYKDNELLTNTGVDET 4366
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217
+++ + AG Y C A N + E I L + I P ++ +V
Sbjct: 4367 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDI-DLIVMIPPEVVPERMNVSTNPRQ 4425
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
+V C G P P + W R + + ++L +L + NV+ D+G Y C A++
Sbjct: 4426 TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGT-TLAIRNVLPDDDGFYHCIAKSD 4484
Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
G A+ L V P P + VE C G+P+ T + +I
Sbjct: 4485 AGQKIATRKLIVNKPSD---RPAPIWVE--------CDEKGKPKKTEY--------MIDR 4525
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
G + D D +L D + + +I Y R TV P
Sbjct: 4526 GDTPD--------DNPQLLPWKDVEDSSLNGSIA-----YRCMPGPRSSRTVLLH--AAP 4570
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
I P N T I ++ C+A P P I W +G+ LI++ + + V +
Sbjct: 4571 QFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAYSHLKVTLN- 4627
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
SDSG YTC+A + G S + VD+ I P
Sbjct: 4628 STSDSGEYTCMAQNSVGSSTVSAFINVDNNILP 4660
Score = 89.8 bits (213), Expect = 1e-17
Identities = 124/473 (26%), Positives = 194/473 (41%), Gaps = 62/473 (13%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGL 66
G AP I+E+P V + TL C A G P PAI WYK L+ + + +
Sbjct: 4315 GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSV 4374
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
F + S AGVY C+A N + + + L + ++ E E + + TV
Sbjct: 4375 IFSSIS----PSQAGVYTCKAEN-WVASTEEDIDL-IVMIPPEVVPERMNVSTNPRQTVF 4428
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G PEP + W ++ + + + + + G L I++ D G Y CIA++ A
Sbjct: 4429 LSC-NATGIPEPVISWMRDSNIAIQNNEK--YQILGTTLAIRNVLPDDDGFYHCIAKSDA 4485
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGNM 244
G + IAT K+ ++ P D A + +C G P ++ R N
Sbjct: 4486 GQK---IATRKL-----IVNKPSDRPA----PIWVECDEKGKPKKTEYMIDRGDTPDDNP 4533
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
L K ++D SL N +A Y C + +S + ++ P + P +
Sbjct: 4534 QLLPWKDVEDSSL---NGSIA----YRC-----MPGPRSSRTVLLHAAPQFIVKPKNTTA 4581
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G + C+A G P PT+ W+ +G +I Y V T+N T +
Sbjct: 4582 AIGAIVELRCSAAGPPHPTITWAKDGK--LIEDSKFEIAYSHLKV-------TLNST--S 4630
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAIC 423
DS C A N GSS V + V ++ P P SNQ K++AV C
Sbjct: 4631 DS-GEYTCMAQNSVGSSTVSAFINV-DNNILPTP---KPSSNQ----KNVAVITCYERNQ 4681
Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKD---LDKSDSGTYTCVASSR 472
+ W + G + +N + N+G+LV+ D L + D YTC +R
Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734
Score = 87.4 bits (207), Expect = 5e-17
Identities = 96/349 (27%), Positives = 138/349 (39%), Gaps = 25/349 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I +P + T A L C A G P P I W K G L + D+ I + L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKL-IEDSKFEIAYSHLKVTLN 4627
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
+T SD+G Y C A NS G ++T+ + + L S Q + V+ C
Sbjct: 4628 ST-----SDSGEYTCMAQNSVG-----SSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA---RQTDAGRYQCIARNAAG 187
+ + W+ NG + + +H ++ G+LVI D ++ D Y C RN
Sbjct: 4678 ERNQAYSRGLTWEYNGVPMP-KNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRN--- 4733
Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPL-PDVLWRRSAGGGNM 244
R +I L + P + T + V G SV C V DPL V+W ++ +
Sbjct: 4734 RRRHSIPHLTSAFEGVPEVKT-IDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN-DQKML 4791
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
+ VL + SL L NV DEG Y C A NS+G L VY S + N
Sbjct: 4792 DDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYGGSSRREAYKKENE 4851
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS--RDKYHATAVFD 351
++ T + T T + I P D YH + D
Sbjct: 4852 DASTTTITTTSPTTTTTETPLTTTIIPALITLPAKQYPTDDYHEGSAND 4900
Score = 82.2 bits (194), Expect = 2e-15
Identities = 109/467 (23%), Positives = 178/467 (38%), Gaps = 52/467 (11%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P ++ + ++V+ Q L+C A G P P I W + + + + + + L A
Sbjct: 4410 PEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTL----A 4465
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ D G Y C A + G + AT + V + R P + +EC
Sbjct: 4466 IRNVLPDDDGFYHCIAKSDAG---QKIATRKLIVNKPSDRPAP----------IWVEC-D 4511
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
+G P+ Y G T D L+ + ++D+ + Y+C+ G R S
Sbjct: 4512 EKGKPKKTEYMIDRGDT----PDDNPQLLPWKD--VEDSSLNGSIAYRCMP----GPRSS 4561
Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
T+ +H P I P++ A G+ V +C G P P + W A G +
Sbjct: 4562 R--TVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITW---AKDGKLIEDSKFE 4616
Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
+ L++ +D GEY+C A+NSVG+ + S ++ V + P+S NVA
Sbjct: 4617 IAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSS---NQKNVAV 4673
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD--KNDSRNT 369
TC + + T + G+ K A F L I DT K
Sbjct: 4674 ITCYERNQ-------AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLEL 4726
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP-EPI 428
C N S +TS + P + T + V C P
Sbjct: 4727 YTCKVRNRRRHSIPH----LTSAFEGVPEVKT--IDKVEVNNGDSVVLDCEVTSDPLTTH 4780
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W + ++ + V + +LVL +++K D G Y CVAS+ GK
Sbjct: 4781 VVWTKNDQKMLDDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGK 4827
Score = 77.8 bits (183), Expect = 4e-14
Identities = 79/334 (23%), Positives = 134/334 (40%), Gaps = 20/334 (5%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
D ++ + AP + T+ R + TL+C I W K G+ + + L
Sbjct: 1817 DFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ-ITWMKQGLPLTENDAIFTL 1875
Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L L A R H D +Y C A N+ G S++ + V VL + + + + +
Sbjct: 1876 DNTRLTILNAN--RDHED--IYTCVANNTAGQV-SKDFDVVVQVL-PKIKNAVVTLEINE 1929
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ ++L C G+P P W N L + + + + +V+ + + G Y+C
Sbjct: 1930 GEEIILTC-DAEGNPTPTAKWDFNQGDLPKEA---VFVNNNHTVVVNNVTKYHTGVYKCY 1985
Query: 182 ARNAAGTRESAIATLKIHI--KPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
A N G A+ T+ +H+ KP +G ++ S+T +C V + W
Sbjct: 1986 ATNKVG---QAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042
Query: 238 SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ V+ L G L + + D G Y+C N G + + L V PP+I
Sbjct: 2043 NGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
V N C TG+P P + W+ +G
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG 2136
Score = 76.6 bits (180), Expect = 1e-13
Identities = 120/515 (23%), Positives = 196/515 (38%), Gaps = 46/515 (8%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
+ TL C G P P I W G +V ++ + L V + G Y C
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQE-GNYHC 1623
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKK 144
A + + + ++VL E ++ + G + L C L + W
Sbjct: 1624 VAQSK---GNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSI 1680
Query: 145 NGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
NG D + + DG L I DA+ + G+Y C N+AG E + TL + ++P
Sbjct: 1681 NGSE--SDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTL-TLDV-LEPP 1736
Query: 204 LITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRL 259
+ P Q + + QC+V G+P P V+W+ GN + + + D+ SL
Sbjct: 1737 VFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKID---GN-DVDKSWLFDESLSLLR 1792
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV--ESGNVARFTCTAT 317
+ + SC AEN G S ++ P+ + + ES + +
Sbjct: 1793 IEKLTGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSL 1852
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G + T W +G P D A D T LTI + ++ D + C A N
Sbjct: 1853 GDFQIT--WMKQG-----LPLTEND---AIFTLDN-TRLTILNANR-DHEDIYTCVANNT 1900
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
AG + V + P I N + + C A P P W F +
Sbjct: 1901 AGQVSKDFDVVV-----QVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDF-NQG 1954
Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
+ V N+ T+V+ ++ K +G Y C A+++ G+ V + ++ + F
Sbjct: 1955 DLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKT----INVHVRTKPRFESG 2010
Query: 498 ADVSSLPGPPTKPIT--HNVTDT-SVTLSWSQNNK 529
S L T+ IT +V D V +SW+ N K
Sbjct: 2011 LTESELTVNLTRSITLECDVDDAIGVGISWTVNGK 2045
>Z47068-9|CAA87336.1| 5198|Caenorhabditis elegans Hypothetical protein
F15G9.4b protein.
Length = 5198
Score = 161 bits (391), Expect = 3e-39
Identities = 145/510 (28%), Positives = 222/510 (43%), Gaps = 30/510 (5%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA +QP + C G P P+I+W K G V D + I+ G + + T AG
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDS---DHAGK 3835
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
+ C A N G + L V ++ ++ A G+T+ L C G+P P + W
Sbjct: 3836 WSCVAENDAGV-KELEMVLDVFT-PPVVSVKSDNPIKALGETITLFC-NASGNPYPQLKW 3892
Query: 143 KKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
K G +L+FD D + G L I ++TD G Y C A NAAGT E+++ ++ + +
Sbjct: 3893 AKGG-SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASV-SVDVLVP 3950
Query: 202 PYLITGPEDVVAQ--TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LR 258
P + D+ + S+T QC G P+P + W + + V D + ++
Sbjct: 3951 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 4010
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
++NV L+D+G Y+C AEN G+ + + V P I+ + + V G +A C G
Sbjct: 4011 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS-NGGTKQVIEGELAVIECLVEG 4069
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
P P + W GNR + G+ +Y V DG +LTI + DS +CSA N A
Sbjct: 4070 YPAPQVSWLRNGNR--VETGVQGVRY----VTDG-RMLTIIEARSLDS-GIYLCSATNEA 4121
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
GS+ L V P IIT+ P T S PC P+PII+W G +
Sbjct: 4122 GSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDI 4177
Query: 439 IQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
+ DGTL ++ ++ Y C A + G V + + P I
Sbjct: 4178 KDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLE--FPVQTIVAPKISTSGN 4234
Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
++ G T I + S SWS+N
Sbjct: 4235 RYINGSEGTET-VIKCEIESESSEFSWSKN 4263
Score = 151 bits (367), Expect = 2e-36
Identities = 123/446 (27%), Positives = 189/446 (42%), Gaps = 29/446 (6%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C G+P P I WY G + ++ + A +R S +GVY C+ATNS G
Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKAD---KSYSGVYTCQATNSAG 1078
Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
+ + ++ +S + D + G P+P + W LL D
Sbjct: 1079 DNEQKTT---IRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITW------LLDD 1129
Query: 153 GDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211
+V + G+L I + + G + C A+NAAG ++ TL +H P + ++
Sbjct: 1130 KPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAG-NDTRTVTLTVHTTPTINAENQEK 1188
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
+A + +C P P LW + L + +DG+L L NV L + G +
Sbjct: 1189 IALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFV 1248
Query: 272 CEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
C+ N G S S LTV++ P I+ P V+V G C ATG PE W+ G
Sbjct: 1249 CQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNG 1308
Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
I M K+ D + L I + DKND N C N AG+S ++T
Sbjct: 1309 ----IDLKMDEKKFSV----DNLGTLRIYEADKNDIGN-YNCVVTNEAGTS----QMTTH 1355
Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-ND 449
D PP I+ + +N T + C +P + W+ G A+ + + V +D
Sbjct: 1356 VDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESD 1415
Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGK 475
GTLV++ D+ YTC AS+ GK
Sbjct: 1416 GTLVIQSASVEDATIYTCKASNPAGK 1441
Score = 141 bits (342), Expect = 2e-33
Identities = 130/510 (25%), Positives = 225/510 (44%), Gaps = 45/510 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
++C+ G P P + W + G + I + +R +D G Y C A+N
Sbjct: 3236 VHCQVTGRPVPYVTWKRNG--------KEIEQFNPVLHIR---NATRADEGKYSCIASNE 3284
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
GTA + L + F + +G++ +EC G P+P + W K G+
Sbjct: 3285 AGTAVAD--FLIDVFTKPTFETHETTFNIVEGESAKIECKID-GHPKPTISWLKGGRP-- 3339
Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-TGPE 209
F+ D+ + G L+I A++ D G Y C+A N+ G E + ++ KPY+ T +
Sbjct: 3340 FNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFK-VNVYTKPYIDETIDQ 3398
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEG 268
A G + +C V G+P P V W+R G +P R ++++ L++++V D G
Sbjct: 3399 TPKAVAGGEIILKCPVLGNPTPTVTWKR--GDDAVPNDSRHTIVNNYDLKINSVTTEDAG 3456
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
+YSC A N G ++ V P+ + N V + C T RP P++ W
Sbjct: 3457 QYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISW- 3515
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
G++ + D+Y + DG + +TIN +D +C A N AG+S + L
Sbjct: 3516 FRGDKPVYL----YDRYSISP--DG-SHITINKAKLSDG-GKYICRASNEAGTSDIDLIL 3567
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVF-PCTAICTPEPIIAWYFEGEALIQNHRRNV 446
+ PP I + L I + ++ C P+P + W G + R +
Sbjct: 3568 KILV----PPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVI 3623
Query: 447 T--NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH-----FFRAAD 499
N+ T ++++ +D G YTC A++R GK +L V SP +IH R D
Sbjct: 3624 LAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGD 3683
Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+L P + ++ D + +SW+++++
Sbjct: 3684 TITLTCP--IKLAEDIADQVMDVSWTKDSR 3711
Score = 138 bits (334), Expect = 2e-32
Identities = 122/451 (27%), Positives = 185/451 (41%), Gaps = 31/451 (6%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
Q TL C A G P P +RW G + T I A F++ + + SD GVY C
Sbjct: 3968 QSLTLQCLAQGKPVPQMRWTLNGTALTHSTP-GITVASDSTFIQINNVSL-SDKGVYTCY 4025
Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
A N G S N +V V++ +KQ +G+ V+ECL G P P V W +NG
Sbjct: 4026 AENVAG---SDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLV-EGYPAPQVSWLRNG 4081
Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
+ ++ DG L I +AR D+G Y C A N AG+ + A TL++ + P +IT
Sbjct: 4082 NRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAY-TLEVLVSPKIIT 4140
Query: 207 G-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
P + +GS + C V G P P + W + + DG+L ++ A
Sbjct: 4141 STPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEK---A 4197
Query: 266 DEGE--YSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVESGNVARFTCTATGRPEP 322
+E Y C A+N GA + + P I+ S N +N G C
Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESE-SS 4256
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
WS G P + + + + + +L+ +D+ + C+A N AG++
Sbjct: 4257 EFSWSKNG-----VPLLPSNNLIFSEDYKLIKILSTRLSDQGE----YSCTAANKAGNAT 4307
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN- 441
+ L V P I P Q + C A P+P I WY + E L
Sbjct: 4308 QKTNLNV-----GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTG 4362
Query: 442 -HRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
T +++ + S +G YTC A +
Sbjct: 4363 VDETATTKKKSVIFSSISPSQAGVYTCKAEN 4393
Score = 137 bits (331), Expect = 5e-32
Identities = 121/463 (26%), Positives = 195/463 (42%), Gaps = 28/463 (6%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + C G P+P + W + G V + G L R D+G+Y C AT
Sbjct: 4061 AVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM-LTIIEAR-SLDSGIYLCSAT 4118
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
N G+A+ TL V V + P + G L C RG P+P + W NG
Sbjct: 4119 NEAGSAQQAY-TLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV-RGYPDPIISWTLNGND 4176
Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYLIT 206
+ DG++ + G L I+ A + Y+C A+N AG T E + T+ + P + T
Sbjct: 4177 IK-DGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTI---VAPKIST 4231
Query: 207 -GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVIL 264
G + G+ +C + + + W ++ G +P + +D L ++ + L
Sbjct: 4232 SGNRYINGSEGTETVIKCEIESES-SEFSWSKN-GVPLLPSNNLIFSEDYKLIKILSTRL 4289
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
+D+GEYSC A N G + L V P I P + V G+ C A+G P+P +
Sbjct: 4290 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAI 4349
Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
W + N + G+ AT V +I+ + C A N+ S+
Sbjct: 4350 TW-YKDNELLTNTGVDET---ATTKKKSVIFSSISPSQAG----VYTCKAENWVASTEED 4401
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
L V PP ++ + T P + C A PEP+I+W + IQN+ +
Sbjct: 4402 IDLIVMI----PPEVVPERMNVSTNP-RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEK 4456
Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
TL ++++ D G Y C+A S G+ + + L+V+ P
Sbjct: 4457 YQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP 4499
Score = 136 bits (329), Expect = 9e-32
Identities = 126/472 (26%), Positives = 200/472 (42%), Gaps = 23/472 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V + E+P I +V+V + A L+C + IRW + G V + + P G
Sbjct: 514 VETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNG 573
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+ H +DAGVY C A N+ G + +R L + + ++ P+ + V
Sbjct: 574 TLKI---HHVTRADAGVYECMARNAGGMS-TRKMRLDI-MEPPSVKVTPQDVYFNMREGV 628
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C G P+P V+W G+ LL D ++ D L I+DA D G Y+C A +
Sbjct: 629 NLSC-EAMGDPKPEVHWYFKGRHLLNDYKYQVGQ-DSKFLYIRDATHHDEGTYECRAMSQ 686
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWRRSAGGGNM 244
AG L + P + ++ G V+F+C+ + G P P + W ++
Sbjct: 687 AGQARDT-TDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIK 745
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
P +K+ ++G L + D G YSC EN G L+V P+I SP++V V
Sbjct: 746 PDDYIKI-NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRV 804
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
C A G P P + W +GN ++ ++ +Y T + DG L I D
Sbjct: 805 NIERQVTLQCLAVGIPPPEIEWQ-KGN--VLLATLNNPRY--TQLADG--NLLITDAQIE 857
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC- 423
D + C A N G L VT P++ + P + L C +
Sbjct: 858 D-QGQFTCIARNTYGQQSQSTTLMVTG---LVSPVLGHVPPEEQLIEGQDLTLSCVVVLG 913
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474
TP+P I W + + + + + G+L+ L+ + D G YTC+A S G
Sbjct: 914 TPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAG 965
Score = 135 bits (327), Expect = 2e-31
Identities = 129/474 (27%), Positives = 202/474 (42%), Gaps = 28/474 (5%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
++++ + T H TL+C A G P P I W+K G + + I+P G L +
Sbjct: 2291 MLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKI 2350
Query: 74 GRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
R+ DAG Y CEA NS G+ + + + E P +S Q + VV+ C P
Sbjct: 2351 TRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC-PV 2409
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT--RE 190
P + W K G+ L D + +G L + R+TD+ +Y CIA N AGT R+
Sbjct: 2410 YARPPAKITWLKAGKPLQSDKFVKTS-ANGQKLYLFKLRETDSSKYTCIATNEAGTDKRD 2468
Query: 191 SAIATL--KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
++ L +P ++ + +G+ T C G P P + W + G P R
Sbjct: 2469 FKVSMLVAPSFDEPNIV---RRITVNSGNPSTLHCPAKGSPSPTITWLKD-GNAIEPNDR 2524
Query: 249 VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSPNSVNVES 306
D G L++ +D+G Y+C A NSVG+ L V PP I+ +V V
Sbjct: 2525 YVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIE 2584
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G + C + + W +G TI + D + + ++ K+DS
Sbjct: 2585 GFSSELFCDSNS-TGVDVEWQKDG-LTINQDTLRGDSF--IQIPSSGKKMSFLSARKSDS 2640
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN---QTLPIKSMAVFPCTAIC 423
C N AG + KL + +D PP I++ S+ QT+ C
Sbjct: 2641 -GRYTCIVRNPAGEA---RKLFDFAVND--PPSISDELSSANIQTIVPYYPVEINCVVSG 2694
Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
+P P + W F+ + L + +TN+G TL + +GTYTC A + GK
Sbjct: 2695 SPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGK 2748
Score = 134 bits (323), Expect = 5e-31
Identities = 135/505 (26%), Positives = 215/505 (42%), Gaps = 57/505 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGL 66
G P IIE P V V + TL C A G P P I W KG VL+ +++ + L G L
Sbjct: 790 GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGNL 849
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTV 125
T ++ D G + C A N+YG +S++ TL V ++ P +Q +G +
Sbjct: 850 LI---TDAQI-EDQGQFTCIARNTYG-QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDL 904
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184
L C+ G+P+P++ W K+ + + + + + GG+L+ ++ D G+Y CIA +
Sbjct: 905 TLSCVVVLGTPKPSIVWIKDDKPV--EEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVS 962
Query: 185 AAGTRESAIATLKIHIKPYLITGPED-----------------VVAQT-----GSSVTFQ 222
AG I +++ KP + PE VV T G
Sbjct: 963 PAGNSTLHI-NVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
C V G P P + W G P R V D +L + + G Y+C+A NS G
Sbjct: 1022 CVVSGTPPPIITWYLD-GRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDN 1080
Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
+ + + P I+ +S N+ ++ C G P+P + W ++
Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD------------ 1128
Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
DK V + LTI + ++ R T C A N AG+ TVT P I
Sbjct: 1129 DKPFTEGVVNEDGSLTIPNVNE-AHRGTFTCHAQNAAGND----TRTVTLTVHTTPTI-- 1181
Query: 402 NGPSNQTLPIKS-MAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDK 459
N + + + +++ V C A P P+ W +EGE + Q + DG LVL+++
Sbjct: 1182 NAENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKL 1241
Query: 460 SDSGTYTCVASSRHGKYVWSGALLV 484
++G + C S+ G+ S L V
Sbjct: 1242 ENTGVFVCQVSNLAGEDSLSYTLTV 1266
Score = 133 bits (322), Expect = 6e-31
Identities = 139/501 (27%), Positives = 212/501 (42%), Gaps = 65/501 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT +P + P + + Q TL+C G+P P+I W K V I G
Sbjct: 881 VTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGG 940
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL---REEFRLEPES----- 116
L LR + + D G Y C A + G N+TLH+ V + EF +PE
Sbjct: 941 SLLRLRGGNPK---DEGKYTCIAVSPAG-----NSTLHINVQLIKKPEFVYKPEGGIVFK 992
Query: 117 --------KQSA---------QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
K A G+ + C+ G+P P + W +G+ + +SR
Sbjct: 993 PTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVS-GTPPPIITWYLDGRPIT--PNSRDFT 1049
Query: 160 VDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
V N L+++ A ++ +G Y C A N+AG E T++I P + G
Sbjct: 1050 VTADNTLIVRKADKSYSGVYTCQATNSAGDNEQK-TTIRIMNTPMISPGQSSFNMVVDDL 1108
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
T C V GDP P + W + P V +DGSL + NV A G ++C A+N+
Sbjct: 1109 FTIPCDVYGDPKPVITWLLD----DKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAA 1164
Query: 279 GAVSASGYLTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR--TII 335
G + + LTV+ P+IN + + +++ ++ C A P P W+ EG + + +
Sbjct: 1165 GNDTRTVTLTVHTTPTINAENQEKIALQNDDIV-LECPAKALPPPVRLWTYEGEKIDSQL 1223
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
P R+ DG VL K ++ VC N AG + LTV
Sbjct: 1224 IPHTIRE--------DGALVL---QNVKLENTGVFVCQVSNLAGEDSLSYTLTV----HE 1268
Query: 396 PPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLV 453
P II+ P + +K + PC A PE I W G L + ++ +V N GTL
Sbjct: 1269 KPKIISEVPGVVDV-VKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR 1327
Query: 454 LKDLDKSDSGTYTCVASSRHG 474
+ + DK+D G Y CV ++ G
Sbjct: 1328 IYEADKNDIGNYNCVVTNEAG 1348
Score = 133 bits (321), Expect = 8e-31
Identities = 129/477 (27%), Positives = 195/477 (40%), Gaps = 40/477 (8%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D YV E P ++ + V + T+ C G+P P + W K G SD +
Sbjct: 3118 DTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTK 3177
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSA 120
L LR T +D G Y C ATN G +++ T V VL R+E E + Q
Sbjct: 3178 LSYL-HLRET---TLADGGTYTCIATNKAGESQT---TTDVEVLVPP-RIEDEERVLQGK 3229
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+G+T ++ C G P P V WK+NG+ + + + V L I++A + D G+Y C
Sbjct: 3230 EGNTYMVHC-QVTGRPVPYVTWKRNGKEI-----EQFNPV----LHIRNATRADEGKYSC 3279
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
IA N AGT A + + KP T G S +C++ G P P + W + G
Sbjct: 3280 IASNEAGT-AVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLK--G 3336
Query: 241 GGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS- 298
G + + + G +L + D G Y+C A NS G + VY P I+ +
Sbjct: 3337 GRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETI 3396
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ +G C G P PT+ W G+ + P SR + +D L I
Sbjct: 3397 DQTPKAVAGGEIILKCPVLGNPTPTVTWK-RGDDAV--PNDSR--HTIVNNYD----LKI 3447
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N D+ C AVN AG+ V P + G + +
Sbjct: 3448 NSVTTEDA-GQYSCIAVNEAGNLTTHYAAEVIG----KPTFVRKGGNLYEVIENDTITMD 3502
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474
C P P I+W+ + + R +++ DG+ + + SD G Y C AS+ G
Sbjct: 3503 CGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAG 3559
Score = 128 bits (310), Expect = 2e-29
Identities = 129/484 (26%), Positives = 191/484 (39%), Gaps = 35/484 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
V + T++C P P+I W++G V SI P G + SD G
Sbjct: 3493 VIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAK---LSDGGK 3549
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVY 141
Y C A+N GT+ + L + V + + A T+ LEC P G P+P+V
Sbjct: 3550 YICRASNEAGTS-DIDLILKILVPPKIDKSNIIGNPLAIVARTIYLEC-PISGIPQPDVI 3607
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
W KNG + DSR+ L I++ + TD GRY C A N G + +
Sbjct: 3608 WTKNGMDINMT-DSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSP 3666
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVG-----GDPLPDVLWRRSAGGGNMPL-GRVKVLDD 254
+ I G + + + G ++T C + D + DV W + + + L V + DD
Sbjct: 3667 PEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDD 3726
Query: 255 G-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVAR 311
G L + L + G Y+C A N G S + + PP I++S N V V
Sbjct: 3727 GRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTI 3786
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
C TG P P++ W G D + V G VL I TD +D
Sbjct: 3787 MRCAVTGHPFPSIKWLKNGKEV-------TDDENIRIVEQG-QVLQILRTD-SDHAGKWS 3837
Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
C A N AG + L V + PP+++ N + C A P P + W
Sbjct: 3838 CVAENDAGVKELEMVLDVFT-----PPVVSVKSDNPIKALGETITLFCNASGNPYPQLKW 3892
Query: 432 YFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
G + + R L + L K+D G YTC A + G ++ VD +
Sbjct: 3893 AKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAG--TSEASVSVDVLVP 3950
Query: 490 PNIH 493
P I+
Sbjct: 3951 PEIN 3954
Score = 124 bits (299), Expect = 4e-28
Identities = 109/455 (23%), Positives = 187/455 (41%), Gaps = 20/455 (4%)
Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
T+ + P +NC GSP P + W + D+ L G L+ +V AG
Sbjct: 2679 TIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET-LKIVRSQVEH-AG 2736
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
Y CEA N+ G AR ++ + V F E E + GDT++L C P +VY
Sbjct: 2737 TYTCEAQNNVGKAR-KDFLVRVTA-PPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVY 2794
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W + +++ + + + L + + + D G Y C A N AG + + I
Sbjct: 2795 WHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIE-T 2853
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
PY + + G +T C G P P +L+ + N V ++ +L +DN
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLN-ESDEVDII-GSTLVIDN 2911
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
EG Y+C AEN G + V PP ++ +V V++G+ C
Sbjct: 2912 PQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSG 2971
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
+ WS + + ++ + ++ + T D D + C AVN AG +
Sbjct: 2972 VHITWSRQFGKDGQLDMRAQSSSDKSKLY--IMQATPEDAD------SYSCIAVNDAGGA 3023
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
++TV + PP I + S + + PC P P I+W+ +G+ +++
Sbjct: 3024 EAVFQVTVNT----PPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEM 3079
Query: 442 HRRNV-TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
D +L + ++ + G YTCVA ++ G+
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGR 3114
Score = 123 bits (297), Expect = 7e-28
Identities = 115/417 (27%), Positives = 170/417 (40%), Gaps = 27/417 (6%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
DAG Y C ++ G + E F + S G+ L C R + E
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPL--GEAAFLHC-STRSAGEV 549
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
+ W + G T+ F+G + G L I + DAG Y+C+ARNA G + L I
Sbjct: 550 EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMR-LDI 607
Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257
P + P+DV V C GDP P+V W G + + +V D L
Sbjct: 608 MEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFK-GRHLLNDYKYQVGQDSKFL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TA 316
+ + DEG Y C A + G + L + PP + + N + V G+ F C T
Sbjct: 667 YIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTI 726
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G+P P + W G + +I P D Y + +G L I K++ C N
Sbjct: 727 RGKPHPKIRWFKNG-KDLIKP----DDY--IKINEGQ--LHIMGA-KDEDAGAYSCVGEN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG L+V R P II + P + I+ C A+ P P I W +G
Sbjct: 777 MAGKDVQVANLSV----GRVPTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGN 830
Query: 437 ALI---QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
L+ N R DG L++ D D G +TC+A + +G+ S L+V ++P
Sbjct: 831 VLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP 887
Score = 121 bits (292), Expect = 3e-27
Identities = 109/470 (23%), Positives = 184/470 (39%), Gaps = 32/470 (6%)
Query: 6 VTSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT P I T + + CR G P P I W+ G ++ +
Sbjct: 3029 VTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMP--GVTYKQ 3086
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G LR + + + + G Y C A N G A ++ + ++ + E + +G
Sbjct: 3087 GDLSLRIDNIKPNQE-GRYTCVAENKAGRAE-QDTYVEISE-PPRVVMASEVMRVVEGRQ 3143
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ C G+PEP V W K+G+ + D L +++ D G Y CIA N
Sbjct: 3144 TTIRC-EVFGNPEPVVNWLKDGEP--YTSDLLQFSTKLSYLHLRETTLADGGTYTCIATN 3200
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG ++ +++ + P + + + G++ C+V G P+P V W+R+
Sbjct: 3201 KAGESQTT-TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN------ 3253
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
G+ + L + N ADEG+YSC A N G A + V+ P+ + N+
Sbjct: 3254 --GKEIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNI 3311
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G A+ C G P+PT+ W ++G R + D + D + +L D
Sbjct: 3312 VEGESAKIECKIDGHPKPTISW-LKGGRP-----FNMDNIILSPRGDTLMILKAQRFD-- 3363
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
C A N G S K+ V + P I + C +
Sbjct: 3364 --GGLYTCVATNSYGDSEQDFKVNVYT----KPYIDETIDQTPKAVAGGEIILKCPVLGN 3417
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P + W +A+ + R + N+ L + + D+G Y+C+A + G
Sbjct: 3418 PTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEAG 3467
Score = 120 bits (288), Expect = 8e-27
Identities = 121/466 (25%), Positives = 184/466 (39%), Gaps = 32/466 (6%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
T+ C G P P I W +L ++ G + + + G + C A N
Sbjct: 1110 TIPCDVYGDPKPVITW----LLDDKPFTEGVVNEDGSLTIPNVN---EAHRGTFTCHAQN 1162
Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
+ G +R TL V E + K + Q D +VLEC P + P P W G+ +
Sbjct: 1163 AAGND-TRTVTLTVHTT-PTINAENQEKIALQNDDIVLEC-PAKALPPPVRLWTYEGEKI 1219
Query: 150 LFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
D H + + G LV+Q+ + + G + C N AG +S TL +H KP +I+
Sbjct: 1220 --DSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAG-EDSLSYTLTVHEKPKIISEV 1276
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
VV G ++ CR G P W ++ M + V + G+LR+ D
Sbjct: 1277 PGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLRIYEADKNDI 1336
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTCTATGRPEPTMFW 326
G Y+C N G + ++ V +PP I S + N G+ C P ++ W
Sbjct: 1337 GNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTW 1396
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
G I G Y V + L I D+ C A N AG + +
Sbjct: 1397 FRRG----IAIGTDTKGY----VVESDGTLVIQSASVEDA-TIYTCKASNPAGKAEANLQ 1447
Query: 387 LTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445
+TV S D + P ++T ++ P C P P I+WY + LI +
Sbjct: 1448 VTVIASPDIKDPDVVTQESIKESHPFS----LYCPVFSNPLPQISWYLNDKPLIDDKTSW 1503
Query: 446 VTNDGTLVLKDLDK--SDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
T+D L +DSG Y CVA + G+ S + V P+N
Sbjct: 1504 KTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLN 1549
Score = 120 bits (288), Expect = 8e-27
Identities = 121/472 (25%), Positives = 188/472 (39%), Gaps = 38/472 (8%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E PY ++Q + + TL+C A G+P P I + K G + I+ G +
Sbjct: 2852 ETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--GSTLVI 2909
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
V G Y C A N G RS + +L + E + + GD + LEC
Sbjct: 2910 DNPQKEVE---GRYTCIAENKAG--RSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLEC 2964
Query: 130 LPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
P + ++ W + G+ D ++ D L I A DA Y CIA N AG
Sbjct: 2965 -PIEDTSGVHITWSRQFGKDGQLDMRAQSSS-DKSKLYIMQATPEDADSYSCIAVNDAGG 3022
Query: 189 RESAIATLKIHIKPYLIT---GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
E A+ + ++ P + ++VA T ++ CR G P P++ W
Sbjct: 3023 AE-AVFQVTVNTPPKIFGDSFSTTEIVADT--TLEIPCRTEGIPPPEISWFLDGKPILEM 3079
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
G D SLR+DN+ EG Y+C AEN G Y+ + +PP + ++ + V
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVV 3139
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G C G PEP + W +G P S +T ++ L + +T D
Sbjct: 3140 EGRQTTIRCEVFGNPEPVVNWLKDGE-----PYTSDLLQFSTK----LSYLHLRETTLAD 3190
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
T C A N AG S T T + PP I + + + C P
Sbjct: 3191 G-GTYTCIATNKAGES-----QTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244
Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
P + W G+ + Q + L +++ ++D G Y+C+AS+ G V
Sbjct: 3245 VPYVTWKRNGKEIEQ-------FNPVLHIRNATRADEGKYSCIASNEAGTAV 3289
Score = 118 bits (285), Expect = 2e-26
Identities = 128/483 (26%), Positives = 203/483 (42%), Gaps = 61/483 (12%)
Query: 23 VARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V R + C+ G P P IRW+K G ++ + G L + G DAG
Sbjct: 713 VGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIM----GAKDEDAG 768
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNV 140
Y C N G +++V R +E P + + V L+CL G P P +
Sbjct: 769 AYSCVGENMAGKDVQ---VANLSVGRVPTIIESPHTVRVNIERQVTLQCLAV-GIPPPEI 824
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH- 199
W+K L + R + GNL+I DA+ D G++ CIARN G ++S TL +
Sbjct: 825 EWQKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYG-QQSQSTTLMVTG 883
Query: 200 -IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGR---VKVLDD 254
+ P L P + G +T C V G P P ++W + + P+ +K+
Sbjct: 884 LVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKD----DKPVEEGPTIKIEGG 939
Query: 255 GS-LRLDNVILADEGEYSCEAENSVG--AVSASGYLT-----VYDPP-SINLSPNSVNVE 305
GS LRL DEG+Y+C A + G + + L VY P I P ++
Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999
Query: 306 SGNVA--------------RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
+VA C +G P P + W ++G I P SRD + TA
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRP--ITPN-SRD-FTVTA--- 1052
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L + DK+ S C A N AG + + + + + P+I+ G S+ + +
Sbjct: 1053 -DNTLIVRKADKSYS-GVYTCQATNSAGDNEQKTTIRIMN-----TPMISPGQSSFNMVV 1105
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
+ PC P+P+I W + + + V DG+L + +++++ GT+TC A +
Sbjct: 1106 DDLFTIPCDVYGDPKPVITWLLDDKPFTEG---VVNEDGSLTIPNVNEAHRGTFTCHAQN 1162
Query: 472 RHG 474
G
Sbjct: 1163 AAG 1165
Score = 116 bits (278), Expect = 1e-25
Identities = 125/466 (26%), Positives = 191/466 (40%), Gaps = 28/466 (6%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++TV + TL C + I W G +++T AGG F L + D
Sbjct: 2015 ELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGVQTLAGGRF-LHIVSAKT-DD 2072
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
G Y C TN G A ++ L V V E + +++VL C G P P
Sbjct: 2073 HGSYACTVTNEAGVA-TKTFNLFVQVPPTIVN-EGGEYTVIENNSLVLPC-EVTGKPNPV 2129
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
V W K+G+ + D S L +G I A G Y C+A+N GT E + + I
Sbjct: 2130 VTWTKDGRPV-GDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEISF-DVDII 2187
Query: 200 IKPYLITGPEDVV-AQTGSSVTFQCRVGGDP--LPDVLWRRSAGGGNMPLGRVKVL---D 253
+P + G +++V A G ++ F+C + D ++W R+ ++ ++ +
Sbjct: 2188 TRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSN 2247
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVA 310
D L + NV DEG+YSC +N G S TV PP+I + N VE V
Sbjct: 2248 DRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVT 2307
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
+C ATG+PEP + W +G I ++ + + + + I + D
Sbjct: 2308 -LSCPATGKPEPDITWFKDG-EAIHIENIADIIPNGELNGNQLKITRIKEGD----AGKY 2361
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AGS + V + P I +G PS+ V C P I
Sbjct: 2362 TCEADNSAGSVEQDVNVNVIT----IPKIEKDGIPSDYESQQNERVVISCPVYARPPAKI 2417
Query: 430 AWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
W G+ L + N L L L ++DS YTC+A++ G
Sbjct: 2418 TWLKAGKPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAG 2463
Score = 110 bits (264), Expect = 7e-24
Identities = 114/460 (24%), Positives = 188/460 (40%), Gaps = 45/460 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C SP ++ W++ G+ + +DT ++ + G +++ DA +Y C+A+N
Sbjct: 1382 LKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE---DATIYTCKASNP 1438
Query: 91 YGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
G A A L V V+ +P+ + + L C P +P P + W N +
Sbjct: 1439 AGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYC-PVFSNPLPQISWYLNDK 1494
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT-----RESAIATLKIHIKP 202
L+ D S D L + A+ TD+G Y+C+ARNAAG + I L +
Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESK 1554
Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSLRL 259
Y + V A+ G VT C V G P+P + W G G D +L
Sbjct: 1555 Y----KKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHF 1610
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TATG 318
D+V + EG Y C A++ + L+V P + N + V G +C T
Sbjct: 1611 DSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDN-LEVFLGKDISLSCDLQTE 1669
Query: 319 RPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
+ T F WS+ G+ + D+ + L I D K ++ +C N
Sbjct: 1670 SDDKTTFVWSINGSES--------DRPDNVQIPSDGHRLYITDA-KPENNGKYMCRVTNS 1720
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + + T+T D PP + +NQ L + + C P+P + W +G
Sbjct: 1721 AG----KAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGN 1776
Query: 437 ALIQNHRRNVTNDGTLVLKDLDK--SDSGTYTCVASSRHG 474
+ ++ D +L L ++K S +C A ++ G
Sbjct: 1777 DV----DKSWLFDESLSLLRIEKLTGKSAQISCTAENKAG 1812
Score = 104 bits (249), Expect = 4e-22
Identities = 98/387 (25%), Positives = 144/387 (37%), Gaps = 20/387 (5%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I P +T + +L C G P P I W G + + + A G +
Sbjct: 4139 ITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAE 4198
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R H +Y C A N G A + + V + ++G V++C
Sbjct: 4199 ER-HL---IYECTAKNDAG-ADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES 4253
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
S E + W KNG LL ++ + D + I R +D G Y C A N AG
Sbjct: 4254 ESSEFS--WSKNGVPLL-PSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQK- 4309
Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVL 252
L + + P ++ P V G VT C G P P + W + N +
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT 4369
Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
S+ ++ + G Y+C+AEN V + L V PP + +V+
Sbjct: 4370 KKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFL 4429
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
+C ATG PEP + W + N I + +KY T L I + +D C
Sbjct: 4430 SCNATGIPEPVISWMRDSNIAI----QNNEKYQILG-----TTLAIRNVLPDDD-GFYHC 4479
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPI 399
A + AG KL V DRP PI
Sbjct: 4480 IAKSDAGQKIATRKLIVNKPSDRPAPI 4506
Score = 98.3 bits (234), Expect = 3e-20
Identities = 109/363 (30%), Positives = 152/363 (41%), Gaps = 31/363 (8%)
Query: 6 VTSGEAPYII-EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63
+T E P II E P V V + + CRA G P W K G+ L + + S+
Sbjct: 1264 LTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNL 1323
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQ 121
G L A +D G Y C TN GT++ T HV V L + +
Sbjct: 1324 GTLRIYEAD----KNDIGNYNCVVTNEAGTSQ---MTTHVDVQEPPIILPSTQTNNTAVV 1376
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQC 180
GD V L+C SP +V W + G + D++ ++V+ G LVIQ A DA Y C
Sbjct: 1377 GDRVELKCY-VEASPPASVTWFRRG--IAIGTDTKGYVVESDGTLVIQSASVEDATIYTC 1433
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ----TGSSVTFQCRVGGDPLPDVLWR 236
A N AG E A L++ + DVV Q + C V +PLP + W
Sbjct: 1434 KASNPAGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWY 1490
Query: 237 RSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
+ K DD L + + D G Y C A N+ G S S + V P ++
Sbjct: 1491 LNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNL 1550
Query: 296 NLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH-ATAVFDG 352
+ S V + G C +G P P + W V+G T++ PG KY AT DG
Sbjct: 1551 DESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDG--TVVEPG---KKYKGATLSNDG 1605
Query: 353 VTV 355
+T+
Sbjct: 1606 LTL 1608
Score = 97.5 bits (232), Expect = 5e-20
Identities = 87/342 (25%), Positives = 139/342 (40%), Gaps = 23/342 (6%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IARNAAGTRESAIATLK 197
+YW K G+ ++ G H D I + DAG Y+C I+ N + ++ + T +
Sbjct: 460 IYWVKTGEDII-GGPLFYHNTDTSVWTIPELSLKDAGEYECRVISNNGNYSVKTRVETRE 518
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR-SAGGGNMPLGRVKVLDDGS 256
P I G +V G + C ++ W R A N P + +G+
Sbjct: 519 ---SPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGP-NTERNPTNGT 574
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
L++ +V AD G Y C A N+ G + L + +PPS+ ++P V +C A
Sbjct: 575 LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEA 634
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G P+P + W +G ++ KY V L I D +D T C A++
Sbjct: 635 MGDPKPEVHWYFKGRHL-----LNDYKYQ---VGQDSKFLYIRDATHHD-EGTYECRAMS 685
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEG 435
AG + L + + PP + + + F C I P P I W+ G
Sbjct: 686 QAGQARDTTDLMLAT-----PPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNG 740
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
+ LI+ N+G L + D+G Y+CV + GK V
Sbjct: 741 KDLIKPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDV 782
Score = 93.5 bits (222), Expect = 8e-19
Identities = 106/471 (22%), Positives = 181/471 (38%), Gaps = 34/471 (7%)
Query: 10 EAPYIIEQPLDVT--VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
E P +E + + + P L C+ G+P P + W G +D +S L L
Sbjct: 1734 EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDG----NDVDKSWLFDESLS 1789
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVV 126
LR ++ + C A N GTA SR+ + + F+ E + + + +T+
Sbjct: 1790 LLRIE--KLTGKSAQISCTAENKAGTA-SRDFFIQ-NIAAPTFKNEGDQETIFRESETIT 1845
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L+C P + + W K G L + D+ + +D L I +A + Y C+A N A
Sbjct: 1846 LDC--PVSLGDFQITWMKQGLPLT-ENDA-IFTLDNTRLTILNANRDHEDIYTCVANNTA 1901
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G + S + + + P + + G + C G+P P W G++P
Sbjct: 1902 G-QVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKW--DFNQGDLPK 1958
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNV 304
V V ++ ++ ++NV G Y C A N VG + + V P L+ + + V
Sbjct: 1959 EAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTV 2018
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
C + W+V G P ++ + G L I K
Sbjct: 2019 NLTRSITLECDVDDAIGVGISWTVNGK-----PFLA--ETDGVQTLAGGRFLHIVSA-KT 2070
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D + C+ N AG + L V + PP I N T+ + V PC
Sbjct: 2071 DDHGSYACTVTNEAGVATKTFNLFV-----QVPPTIVNEGGEYTVIENNSLVLPCEVTGK 2125
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
P P++ W +G + V ++G + + + G+Y C+A + G
Sbjct: 2126 PNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVG 2176
Score = 92.7 bits (220), Expect = 1e-18
Identities = 114/453 (25%), Positives = 176/453 (38%), Gaps = 45/453 (9%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
S S W K GV ++ + L + +T SD G Y C A N G A ++
Sbjct: 4253 SESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTR---LSDQGEYSCTAANKAGNA-TQ 4308
Query: 98 NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
L+V V + P ++ +GD V L C G P+P + W K+ + L G
Sbjct: 4309 KTNLNVGVAPKIME-RPRTQVVHKGDQVTLWC-EASGVPQPAITWYKDNELLTNTGVDET 4366
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217
+++ + AG Y C A N + E I L + I P ++ +V
Sbjct: 4367 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDI-DLIVMIPPEVVPERMNVSTNPRQ 4425
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
+V C G P P + W R + + ++L +L + NV+ D+G Y C A++
Sbjct: 4426 TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGT-TLAIRNVLPDDDGFYHCIAKSD 4484
Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
G A+ L V P P + VE C G+P+ T + +I
Sbjct: 4485 AGQKIATRKLIVNKPSD---RPAPIWVE--------CDEKGKPKKTEY--------MIDR 4525
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
G + D D +L D + + +I Y R TV P
Sbjct: 4526 GDTPD--------DNPQLLPWKDVEDSSLNGSIA-----YRCMPGPRSSRTVLLH--AAP 4570
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
I P N T I ++ C+A P P I W +G+ LI++ + + V +
Sbjct: 4571 QFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAYSHLKVTLN- 4627
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
SDSG YTC+A + G S + VD+ I P
Sbjct: 4628 STSDSGEYTCMAQNSVGSSTVSAFINVDNNILP 4660
Score = 89.8 bits (213), Expect = 1e-17
Identities = 124/473 (26%), Positives = 194/473 (41%), Gaps = 62/473 (13%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGL 66
G AP I+E+P V + TL C A G P PAI WYK L+ + + +
Sbjct: 4315 GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSV 4374
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
F + S AGVY C+A N + + + L + ++ E E + + TV
Sbjct: 4375 IFSSIS----PSQAGVYTCKAEN-WVASTEEDIDL-IVMIPPEVVPERMNVSTNPRQTVF 4428
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G PEP + W ++ + + + + + G L I++ D G Y CIA++ A
Sbjct: 4429 LSC-NATGIPEPVISWMRDSNIAIQNNEK--YQILGTTLAIRNVLPDDDGFYHCIAKSDA 4485
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGNM 244
G + IAT K+ ++ P D A + +C G P ++ R N
Sbjct: 4486 GQK---IATRKL-----IVNKPSDRPA----PIWVECDEKGKPKKTEYMIDRGDTPDDNP 4533
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
L K ++D SL N +A Y C + +S + ++ P + P +
Sbjct: 4534 QLLPWKDVEDSSL---NGSIA----YRC-----MPGPRSSRTVLLHAAPQFIVKPKNTTA 4581
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G + C+A G P PT+ W+ +G +I Y V T+N T +
Sbjct: 4582 AIGAIVELRCSAAGPPHPTITWAKDGK--LIEDSKFEIAYSHLKV-------TLNST--S 4630
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAIC 423
DS C A N GSS V + V ++ P P SNQ K++AV C
Sbjct: 4631 DS-GEYTCMAQNSVGSSTVSAFINV-DNNILPTP---KPSSNQ----KNVAVITCYERNQ 4681
Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKD---LDKSDSGTYTCVASSR 472
+ W + G + +N + N+G+LV+ D L + D YTC +R
Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734
Score = 88.2 bits (209), Expect = 3e-17
Identities = 88/309 (28%), Positives = 130/309 (42%), Gaps = 26/309 (8%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I +P + T A L C A G P P I W K G L + D+ I + L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKL-IEDSKFEIAYSHLKVTLN 4627
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
+T SD+G Y C A NS G ++T+ + + L S Q + V+ C
Sbjct: 4628 ST-----SDSGEYTCMAQNSVG-----SSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA---RQTDAGRYQCIARNAAG 187
+ + W+ NG + + +H ++ G+LVI D ++ D Y C RN
Sbjct: 4678 ERNQAYSRGLTWEYNGVPMP-KNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRN--- 4733
Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPL-PDVLWRRSAGGGNM 244
R +I L + P + T + V G SV C V DPL V+W ++ +
Sbjct: 4734 RRRHSIPHLTSAFEGVPEVKT-IDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN-DQKML 4791
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSPNS 301
+ VL + SL L NV DEG Y C A NS+G L VY+ P +
Sbjct: 4792 DDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSG 4851
Query: 302 VNVESGNVA 310
+N++ + A
Sbjct: 4852 INIDDSSNA 4860
Score = 82.2 bits (194), Expect = 2e-15
Identities = 109/467 (23%), Positives = 178/467 (38%), Gaps = 52/467 (11%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P ++ + ++V+ Q L+C A G P P I W + + + + + + L A
Sbjct: 4410 PEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTL----A 4465
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ D G Y C A + G + AT + V + R P + +EC
Sbjct: 4466 IRNVLPDDDGFYHCIAKSDAG---QKIATRKLIVNKPSDRPAP----------IWVEC-D 4511
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
+G P+ Y G T D L+ + ++D+ + Y+C+ G R S
Sbjct: 4512 EKGKPKKTEYMIDRGDT----PDDNPQLLPWKD--VEDSSLNGSIAYRCMP----GPRSS 4561
Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
T+ +H P I P++ A G+ V +C G P P + W A G +
Sbjct: 4562 R--TVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITW---AKDGKLIEDSKFE 4616
Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
+ L++ +D GEY+C A+NSVG+ + S ++ V + P+S NVA
Sbjct: 4617 IAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSS---NQKNVAV 4673
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD--KNDSRNT 369
TC + + T + G+ K A F L I DT K
Sbjct: 4674 ITCYERNQ-------AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLEL 4726
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP-EPI 428
C N S +TS + P + T + V C P
Sbjct: 4727 YTCKVRNRRRHSIPH----LTSAFEGVPEVKT--IDKVEVNNGDSVVLDCEVTSDPLTTH 4780
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W + ++ + V + +LVL +++K D G Y CVAS+ GK
Sbjct: 4781 VVWTKNDQKMLDDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGK 4827
Score = 77.8 bits (183), Expect = 4e-14
Identities = 79/334 (23%), Positives = 134/334 (40%), Gaps = 20/334 (5%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
D ++ + AP + T+ R + TL+C I W K G+ + + L
Sbjct: 1817 DFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ-ITWMKQGLPLTENDAIFTL 1875
Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L L A R H D +Y C A N+ G S++ + V VL + + + + +
Sbjct: 1876 DNTRLTILNAN--RDHED--IYTCVANNTAGQV-SKDFDVVVQVL-PKIKNAVVTLEINE 1929
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ ++L C G+P P W N L + + + + +V+ + + G Y+C
Sbjct: 1930 GEEIILTC-DAEGNPTPTAKWDFNQGDLPKEA---VFVNNNHTVVVNNVTKYHTGVYKCY 1985
Query: 182 ARNAAGTRESAIATLKIHI--KPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
A N G A+ T+ +H+ KP +G ++ S+T +C V + W
Sbjct: 1986 ATNKVG---QAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042
Query: 238 SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ V+ L G L + + D G Y+C N G + + L V PP+I
Sbjct: 2043 NGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
V N C TG+P P + W+ +G
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG 2136
Score = 76.6 bits (180), Expect = 1e-13
Identities = 120/515 (23%), Positives = 196/515 (38%), Gaps = 46/515 (8%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
+ TL C G P P I W G +V ++ + L V + G Y C
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQE-GNYHC 1623
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKK 144
A + + + ++VL E ++ + G + L C L + W
Sbjct: 1624 VAQSK---GNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSI 1680
Query: 145 NGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
NG D + + DG L I DA+ + G+Y C N+AG E + TL + ++P
Sbjct: 1681 NGSE--SDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTL-TLDV-LEPP 1736
Query: 204 LITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRL 259
+ P Q + + QC+V G+P P V+W+ GN + + + D+ SL
Sbjct: 1737 VFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKID---GN-DVDKSWLFDESLSLLR 1792
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV--ESGNVARFTCTAT 317
+ + SC AEN G S ++ P+ + + ES + +
Sbjct: 1793 IEKLTGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSL 1852
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G + T W +G P D A D T LTI + ++ D + C A N
Sbjct: 1853 GDFQIT--WMKQG-----LPLTEND---AIFTLDN-TRLTILNANR-DHEDIYTCVANNT 1900
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
AG + V + P I N + + C A P P W F +
Sbjct: 1901 AGQVSKDFDVVV-----QVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDF-NQG 1954
Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
+ V N+ T+V+ ++ K +G Y C A+++ G+ V + ++ + F
Sbjct: 1955 DLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKT----INVHVRTKPRFESG 2010
Query: 498 ADVSSLPGPPTKPIT--HNVTDT-SVTLSWSQNNK 529
S L T+ IT +V D V +SW+ N K
Sbjct: 2011 LTESELTVNLTRSITLECDVDDAIGVGISWTVNGK 2045
>Z47068-8|CAA87335.1| 5175|Caenorhabditis elegans Hypothetical protein
F15G9.4a protein.
Length = 5175
Score = 161 bits (391), Expect = 3e-39
Identities = 145/510 (28%), Positives = 222/510 (43%), Gaps = 30/510 (5%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA +QP + C G P P+I+W K G V D + I+ G + + T AG
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDS---DHAGK 3835
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
+ C A N G + L V ++ ++ A G+T+ L C G+P P + W
Sbjct: 3836 WSCVAENDAGV-KELEMVLDVFT-PPVVSVKSDNPIKALGETITLFC-NASGNPYPQLKW 3892
Query: 143 KKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
K G +L+FD D + G L I ++TD G Y C A NAAGT E+++ ++ + +
Sbjct: 3893 AKGG-SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASV-SVDVLVP 3950
Query: 202 PYLITGPEDVVAQ--TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LR 258
P + D+ + S+T QC G P+P + W + + V D + ++
Sbjct: 3951 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 4010
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
++NV L+D+G Y+C AEN G+ + + V P I+ + + V G +A C G
Sbjct: 4011 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS-NGGTKQVIEGELAVIECLVEG 4069
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
P P + W GNR + G+ +Y V DG +LTI + DS +CSA N A
Sbjct: 4070 YPAPQVSWLRNGNR--VETGVQGVRY----VTDG-RMLTIIEARSLDS-GIYLCSATNEA 4121
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
GS+ L V P IIT+ P T S PC P+PII+W G +
Sbjct: 4122 GSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDI 4177
Query: 439 IQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
+ DGTL ++ ++ Y C A + G V + + P I
Sbjct: 4178 KDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLE--FPVQTIVAPKISTSGN 4234
Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
++ G T I + S SWS+N
Sbjct: 4235 RYINGSEGTET-VIKCEIESESSEFSWSKN 4263
Score = 151 bits (367), Expect = 2e-36
Identities = 123/446 (27%), Positives = 189/446 (42%), Gaps = 29/446 (6%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C G+P P I WY G + ++ + A +R S +GVY C+ATNS G
Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKAD---KSYSGVYTCQATNSAG 1078
Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
+ + ++ +S + D + G P+P + W LL D
Sbjct: 1079 DNEQKTT---IRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITW------LLDD 1129
Query: 153 GDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211
+V + G+L I + + G + C A+NAAG ++ TL +H P + ++
Sbjct: 1130 KPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAG-NDTRTVTLTVHTTPTINAENQEK 1188
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
+A + +C P P LW + L + +DG+L L NV L + G +
Sbjct: 1189 IALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFV 1248
Query: 272 CEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
C+ N G S S LTV++ P I+ P V+V G C ATG PE W+ G
Sbjct: 1249 CQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNG 1308
Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
I M K+ D + L I + DKND N C N AG+S ++T
Sbjct: 1309 ----IDLKMDEKKFSV----DNLGTLRIYEADKNDIGN-YNCVVTNEAGTS----QMTTH 1355
Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-ND 449
D PP I+ + +N T + C +P + W+ G A+ + + V +D
Sbjct: 1356 VDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESD 1415
Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGK 475
GTLV++ D+ YTC AS+ GK
Sbjct: 1416 GTLVIQSASVEDATIYTCKASNPAGK 1441
Score = 141 bits (342), Expect = 2e-33
Identities = 130/510 (25%), Positives = 225/510 (44%), Gaps = 45/510 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
++C+ G P P + W + G + I + +R +D G Y C A+N
Sbjct: 3236 VHCQVTGRPVPYVTWKRNG--------KEIEQFNPVLHIR---NATRADEGKYSCIASNE 3284
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
GTA + L + F + +G++ +EC G P+P + W K G+
Sbjct: 3285 AGTAVAD--FLIDVFTKPTFETHETTFNIVEGESAKIECKID-GHPKPTISWLKGGRP-- 3339
Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-TGPE 209
F+ D+ + G L+I A++ D G Y C+A N+ G E + ++ KPY+ T +
Sbjct: 3340 FNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFK-VNVYTKPYIDETIDQ 3398
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEG 268
A G + +C V G+P P V W+R G +P R ++++ L++++V D G
Sbjct: 3399 TPKAVAGGEIILKCPVLGNPTPTVTWKR--GDDAVPNDSRHTIVNNYDLKINSVTTEDAG 3456
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
+YSC A N G ++ V P+ + N V + C T RP P++ W
Sbjct: 3457 QYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISW- 3515
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
G++ + D+Y + DG + +TIN +D +C A N AG+S + L
Sbjct: 3516 FRGDKPVYL----YDRYSISP--DG-SHITINKAKLSDG-GKYICRASNEAGTSDIDLIL 3567
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVF-PCTAICTPEPIIAWYFEGEALIQNHRRNV 446
+ PP I + L I + ++ C P+P + W G + R +
Sbjct: 3568 KILV----PPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVI 3623
Query: 447 T--NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH-----FFRAAD 499
N+ T ++++ +D G YTC A++R GK +L V SP +IH R D
Sbjct: 3624 LAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGD 3683
Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+L P + ++ D + +SW+++++
Sbjct: 3684 TITLTCP--IKLAEDIADQVMDVSWTKDSR 3711
Score = 138 bits (334), Expect = 2e-32
Identities = 122/451 (27%), Positives = 185/451 (41%), Gaps = 31/451 (6%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
Q TL C A G P P +RW G + T I A F++ + + SD GVY C
Sbjct: 3968 QSLTLQCLAQGKPVPQMRWTLNGTALTHSTP-GITVASDSTFIQINNVSL-SDKGVYTCY 4025
Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
A N G S N +V V++ +KQ +G+ V+ECL G P P V W +NG
Sbjct: 4026 AENVAG---SDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLV-EGYPAPQVSWLRNG 4081
Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
+ ++ DG L I +AR D+G Y C A N AG+ + A TL++ + P +IT
Sbjct: 4082 NRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAY-TLEVLVSPKIIT 4140
Query: 207 G-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
P + +GS + C V G P P + W + + DG+L ++ A
Sbjct: 4141 STPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEK---A 4197
Query: 266 DEGE--YSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVESGNVARFTCTATGRPEP 322
+E Y C A+N GA + + P I+ S N +N G C
Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESE-SS 4256
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
WS G P + + + + + +L+ +D+ + C+A N AG++
Sbjct: 4257 EFSWSKNG-----VPLLPSNNLIFSEDYKLIKILSTRLSDQGE----YSCTAANKAGNAT 4307
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN- 441
+ L V P I P Q + C A P+P I WY + E L
Sbjct: 4308 QKTNLNV-----GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTG 4362
Query: 442 -HRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
T +++ + S +G YTC A +
Sbjct: 4363 VDETATTKKKSVIFSSISPSQAGVYTCKAEN 4393
Score = 137 bits (331), Expect = 5e-32
Identities = 121/463 (26%), Positives = 195/463 (42%), Gaps = 28/463 (6%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + C G P+P + W + G V + G L R D+G+Y C AT
Sbjct: 4061 AVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM-LTIIEAR-SLDSGIYLCSAT 4118
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
N G+A+ TL V V + P + G L C RG P+P + W NG
Sbjct: 4119 NEAGSAQQAY-TLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV-RGYPDPIISWTLNGND 4176
Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYLIT 206
+ DG++ + G L I+ A + Y+C A+N AG T E + T+ + P + T
Sbjct: 4177 IK-DGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTI---VAPKIST 4231
Query: 207 -GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVIL 264
G + G+ +C + + + W ++ G +P + +D L ++ + L
Sbjct: 4232 SGNRYINGSEGTETVIKCEIESES-SEFSWSKN-GVPLLPSNNLIFSEDYKLIKILSTRL 4289
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
+D+GEYSC A N G + L V P I P + V G+ C A+G P+P +
Sbjct: 4290 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAI 4349
Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
W + N + G+ AT V +I+ + C A N+ S+
Sbjct: 4350 TW-YKDNELLTNTGVDET---ATTKKKSVIFSSISPSQAG----VYTCKAENWVASTEED 4401
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
L V PP ++ + T P + C A PEP+I+W + IQN+ +
Sbjct: 4402 IDLIVMI----PPEVVPERMNVSTNP-RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEK 4456
Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
TL ++++ D G Y C+A S G+ + + L+V+ P
Sbjct: 4457 YQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP 4499
Score = 136 bits (329), Expect = 9e-32
Identities = 126/472 (26%), Positives = 200/472 (42%), Gaps = 23/472 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V + E+P I +V+V + A L+C + IRW + G V + + P G
Sbjct: 514 VETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNG 573
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+ H +DAGVY C A N+ G + +R L + + ++ P+ + V
Sbjct: 574 TLKI---HHVTRADAGVYECMARNAGGMS-TRKMRLDI-MEPPSVKVTPQDVYFNMREGV 628
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C G P+P V+W G+ LL D ++ D L I+DA D G Y+C A +
Sbjct: 629 NLSC-EAMGDPKPEVHWYFKGRHLLNDYKYQVGQ-DSKFLYIRDATHHDEGTYECRAMSQ 686
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWRRSAGGGNM 244
AG L + P + ++ G V+F+C+ + G P P + W ++
Sbjct: 687 AGQARDT-TDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIK 745
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
P +K+ ++G L + D G YSC EN G L+V P+I SP++V V
Sbjct: 746 PDDYIKI-NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRV 804
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
C A G P P + W +GN ++ ++ +Y T + DG L I D
Sbjct: 805 NIERQVTLQCLAVGIPPPEIEWQ-KGN--VLLATLNNPRY--TQLADG--NLLITDAQIE 857
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC- 423
D + C A N G L VT P++ + P + L C +
Sbjct: 858 D-QGQFTCIARNTYGQQSQSTTLMVTG---LVSPVLGHVPPEEQLIEGQDLTLSCVVVLG 913
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474
TP+P I W + + + + + G+L+ L+ + D G YTC+A S G
Sbjct: 914 TPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAG 965
Score = 135 bits (327), Expect = 2e-31
Identities = 129/474 (27%), Positives = 202/474 (42%), Gaps = 28/474 (5%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
++++ + T H TL+C A G P P I W+K G + + I+P G L +
Sbjct: 2291 MLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKI 2350
Query: 74 GRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
R+ DAG Y CEA NS G+ + + + E P +S Q + VV+ C P
Sbjct: 2351 TRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC-PV 2409
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT--RE 190
P + W K G+ L D + +G L + R+TD+ +Y CIA N AGT R+
Sbjct: 2410 YARPPAKITWLKAGKPLQSDKFVKTS-ANGQKLYLFKLRETDSSKYTCIATNEAGTDKRD 2468
Query: 191 SAIATL--KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
++ L +P ++ + +G+ T C G P P + W + G P R
Sbjct: 2469 FKVSMLVAPSFDEPNIV---RRITVNSGNPSTLHCPAKGSPSPTITWLKD-GNAIEPNDR 2524
Query: 249 VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSPNSVNVES 306
D G L++ +D+G Y+C A NSVG+ L V PP I+ +V V
Sbjct: 2525 YVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIE 2584
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G + C + + W +G TI + D + + ++ K+DS
Sbjct: 2585 GFSSELFCDSNS-TGVDVEWQKDG-LTINQDTLRGDSF--IQIPSSGKKMSFLSARKSDS 2640
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN---QTLPIKSMAVFPCTAIC 423
C N AG + KL + +D PP I++ S+ QT+ C
Sbjct: 2641 -GRYTCIVRNPAGEA---RKLFDFAVND--PPSISDELSSANIQTIVPYYPVEINCVVSG 2694
Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
+P P + W F+ + L + +TN+G TL + +GTYTC A + GK
Sbjct: 2695 SPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGK 2748
Score = 134 bits (323), Expect = 5e-31
Identities = 135/505 (26%), Positives = 215/505 (42%), Gaps = 57/505 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGL 66
G P IIE P V V + TL C A G P P I W KG VL+ +++ + L G L
Sbjct: 790 GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGNL 849
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTV 125
T ++ D G + C A N+YG +S++ TL V ++ P +Q +G +
Sbjct: 850 LI---TDAQI-EDQGQFTCIARNTYG-QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDL 904
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184
L C+ G+P+P++ W K+ + + + + + GG+L+ ++ D G+Y CIA +
Sbjct: 905 TLSCVVVLGTPKPSIVWIKDDKPV--EEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVS 962
Query: 185 AAGTRESAIATLKIHIKPYLITGPED-----------------VVAQT-----GSSVTFQ 222
AG I +++ KP + PE VV T G
Sbjct: 963 PAGNSTLHI-NVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
C V G P P + W G P R V D +L + + G Y+C+A NS G
Sbjct: 1022 CVVSGTPPPIITWYLD-GRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDN 1080
Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
+ + + P I+ +S N+ ++ C G P+P + W ++
Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD------------ 1128
Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
DK V + LTI + ++ R T C A N AG+ TVT P I
Sbjct: 1129 DKPFTEGVVNEDGSLTIPNVNE-AHRGTFTCHAQNAAGND----TRTVTLTVHTTPTI-- 1181
Query: 402 NGPSNQTLPIKS-MAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDK 459
N + + + +++ V C A P P+ W +EGE + Q + DG LVL+++
Sbjct: 1182 NAENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKL 1241
Query: 460 SDSGTYTCVASSRHGKYVWSGALLV 484
++G + C S+ G+ S L V
Sbjct: 1242 ENTGVFVCQVSNLAGEDSLSYTLTV 1266
Score = 133 bits (322), Expect = 6e-31
Identities = 139/501 (27%), Positives = 212/501 (42%), Gaps = 65/501 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT +P + P + + Q TL+C G+P P+I W K V I G
Sbjct: 881 VTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGG 940
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL---REEFRLEPES----- 116
L LR + + D G Y C A + G N+TLH+ V + EF +PE
Sbjct: 941 SLLRLRGGNPK---DEGKYTCIAVSPAG-----NSTLHINVQLIKKPEFVYKPEGGIVFK 992
Query: 117 --------KQSA---------QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
K A G+ + C+ G+P P + W +G+ + +SR
Sbjct: 993 PTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVS-GTPPPIITWYLDGRPIT--PNSRDFT 1049
Query: 160 VDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
V N L+++ A ++ +G Y C A N+AG E T++I P + G
Sbjct: 1050 VTADNTLIVRKADKSYSGVYTCQATNSAGDNEQK-TTIRIMNTPMISPGQSSFNMVVDDL 1108
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
T C V GDP P + W + P V +DGSL + NV A G ++C A+N+
Sbjct: 1109 FTIPCDVYGDPKPVITWLLD----DKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAA 1164
Query: 279 GAVSASGYLTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR--TII 335
G + + LTV+ P+IN + + +++ ++ C A P P W+ EG + + +
Sbjct: 1165 GNDTRTVTLTVHTTPTINAENQEKIALQNDDIV-LECPAKALPPPVRLWTYEGEKIDSQL 1223
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
P R+ DG VL K ++ VC N AG + LTV
Sbjct: 1224 IPHTIRE--------DGALVL---QNVKLENTGVFVCQVSNLAGEDSLSYTLTV----HE 1268
Query: 396 PPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLV 453
P II+ P + +K + PC A PE I W G L + ++ +V N GTL
Sbjct: 1269 KPKIISEVPGVVDV-VKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR 1327
Query: 454 LKDLDKSDSGTYTCVASSRHG 474
+ + DK+D G Y CV ++ G
Sbjct: 1328 IYEADKNDIGNYNCVVTNEAG 1348
Score = 133 bits (321), Expect = 8e-31
Identities = 129/477 (27%), Positives = 195/477 (40%), Gaps = 40/477 (8%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D YV E P ++ + V + T+ C G+P P + W K G SD +
Sbjct: 3118 DTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTK 3177
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSA 120
L LR T +D G Y C ATN G +++ T V VL R+E E + Q
Sbjct: 3178 LSYL-HLRET---TLADGGTYTCIATNKAGESQT---TTDVEVLVPP-RIEDEERVLQGK 3229
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+G+T ++ C G P P V WK+NG+ + + + V L I++A + D G+Y C
Sbjct: 3230 EGNTYMVHC-QVTGRPVPYVTWKRNGKEI-----EQFNPV----LHIRNATRADEGKYSC 3279
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
IA N AGT A + + KP T G S +C++ G P P + W + G
Sbjct: 3280 IASNEAGT-AVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLK--G 3336
Query: 241 GGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS- 298
G + + + G +L + D G Y+C A NS G + VY P I+ +
Sbjct: 3337 GRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETI 3396
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ +G C G P PT+ W G+ + P SR + +D L I
Sbjct: 3397 DQTPKAVAGGEIILKCPVLGNPTPTVTWK-RGDDAV--PNDSR--HTIVNNYD----LKI 3447
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N D+ C AVN AG+ V P + G + +
Sbjct: 3448 NSVTTEDA-GQYSCIAVNEAGNLTTHYAAEVIG----KPTFVRKGGNLYEVIENDTITMD 3502
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474
C P P I+W+ + + R +++ DG+ + + SD G Y C AS+ G
Sbjct: 3503 CGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAG 3559
Score = 128 bits (310), Expect = 2e-29
Identities = 129/484 (26%), Positives = 191/484 (39%), Gaps = 35/484 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
V + T++C P P+I W++G V SI P G + SD G
Sbjct: 3493 VIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAK---LSDGGK 3549
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVY 141
Y C A+N GT+ + L + V + + A T+ LEC P G P+P+V
Sbjct: 3550 YICRASNEAGTS-DIDLILKILVPPKIDKSNIIGNPLAIVARTIYLEC-PISGIPQPDVI 3607
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
W KNG + DSR+ L I++ + TD GRY C A N G + +
Sbjct: 3608 WTKNGMDINMT-DSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSP 3666
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVG-----GDPLPDVLWRRSAGGGNMPL-GRVKVLDD 254
+ I G + + + G ++T C + D + DV W + + + L V + DD
Sbjct: 3667 PEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDD 3726
Query: 255 G-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVAR 311
G L + L + G Y+C A N G S + + PP I++S N V V
Sbjct: 3727 GRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTI 3786
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
C TG P P++ W G D + V G VL I TD +D
Sbjct: 3787 MRCAVTGHPFPSIKWLKNGKEV-------TDDENIRIVEQG-QVLQILRTD-SDHAGKWS 3837
Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
C A N AG + L V + PP+++ N + C A P P + W
Sbjct: 3838 CVAENDAGVKELEMVLDVFT-----PPVVSVKSDNPIKALGETITLFCNASGNPYPQLKW 3892
Query: 432 YFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
G + + R L + L K+D G YTC A + G ++ VD +
Sbjct: 3893 AKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAG--TSEASVSVDVLVP 3950
Query: 490 PNIH 493
P I+
Sbjct: 3951 PEIN 3954
Score = 124 bits (299), Expect = 4e-28
Identities = 109/455 (23%), Positives = 187/455 (41%), Gaps = 20/455 (4%)
Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
T+ + P +NC GSP P + W + D+ L G L+ +V AG
Sbjct: 2679 TIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET-LKIVRSQVEH-AG 2736
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
Y CEA N+ G AR ++ + V F E E + GDT++L C P +VY
Sbjct: 2737 TYTCEAQNNVGKAR-KDFLVRVTA-PPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVY 2794
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W + +++ + + + L + + + D G Y C A N AG + + I
Sbjct: 2795 WHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIE-T 2853
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
PY + + G +T C G P P +L+ + N V ++ +L +DN
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLN-ESDEVDII-GSTLVIDN 2911
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
EG Y+C AEN G + V PP ++ +V V++G+ C
Sbjct: 2912 PQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSG 2971
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
+ WS + + ++ + ++ + T D D + C AVN AG +
Sbjct: 2972 VHITWSRQFGKDGQLDMRAQSSSDKSKLY--IMQATPEDAD------SYSCIAVNDAGGA 3023
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
++TV + PP I + S + + PC P P I+W+ +G+ +++
Sbjct: 3024 EAVFQVTVNT----PPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEM 3079
Query: 442 HRRNV-TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
D +L + ++ + G YTCVA ++ G+
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGR 3114
Score = 123 bits (297), Expect = 7e-28
Identities = 115/417 (27%), Positives = 170/417 (40%), Gaps = 27/417 (6%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
DAG Y C ++ G + E F + S G+ L C R + E
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPL--GEAAFLHC-STRSAGEV 549
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
+ W + G T+ F+G + G L I + DAG Y+C+ARNA G + L I
Sbjct: 550 EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMR-LDI 607
Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257
P + P+DV V C GDP P+V W G + + +V D L
Sbjct: 608 MEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFK-GRHLLNDYKYQVGQDSKFL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TA 316
+ + DEG Y C A + G + L + PP + + N + V G+ F C T
Sbjct: 667 YIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTI 726
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G+P P + W G + +I P D Y + +G L I K++ C N
Sbjct: 727 RGKPHPKIRWFKNG-KDLIKP----DDY--IKINEGQ--LHIMGA-KDEDAGAYSCVGEN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG L+V R P II + P + I+ C A+ P P I W +G
Sbjct: 777 MAGKDVQVANLSV----GRVPTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGN 830
Query: 437 ALI---QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
L+ N R DG L++ D D G +TC+A + +G+ S L+V ++P
Sbjct: 831 VLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP 887
Score = 121 bits (292), Expect = 3e-27
Identities = 109/470 (23%), Positives = 184/470 (39%), Gaps = 32/470 (6%)
Query: 6 VTSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT P I T + + CR G P P I W+ G ++ +
Sbjct: 3029 VTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMP--GVTYKQ 3086
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G LR + + + + G Y C A N G A ++ + ++ + E + +G
Sbjct: 3087 GDLSLRIDNIKPNQE-GRYTCVAENKAGRAE-QDTYVEISE-PPRVVMASEVMRVVEGRQ 3143
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ C G+PEP V W K+G+ + D L +++ D G Y CIA N
Sbjct: 3144 TTIRC-EVFGNPEPVVNWLKDGEP--YTSDLLQFSTKLSYLHLRETTLADGGTYTCIATN 3200
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG ++ +++ + P + + + G++ C+V G P+P V W+R+
Sbjct: 3201 KAGESQTT-TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN------ 3253
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
G+ + L + N ADEG+YSC A N G A + V+ P+ + N+
Sbjct: 3254 --GKEIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNI 3311
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G A+ C G P+PT+ W ++G R + D + D + +L D
Sbjct: 3312 VEGESAKIECKIDGHPKPTISW-LKGGRP-----FNMDNIILSPRGDTLMILKAQRFD-- 3363
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
C A N G S K+ V + P I + C +
Sbjct: 3364 --GGLYTCVATNSYGDSEQDFKVNVYT----KPYIDETIDQTPKAVAGGEIILKCPVLGN 3417
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P + W +A+ + R + N+ L + + D+G Y+C+A + G
Sbjct: 3418 PTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEAG 3467
Score = 120 bits (288), Expect = 8e-27
Identities = 121/466 (25%), Positives = 184/466 (39%), Gaps = 32/466 (6%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
T+ C G P P I W +L ++ G + + + G + C A N
Sbjct: 1110 TIPCDVYGDPKPVITW----LLDDKPFTEGVVNEDGSLTIPNVN---EAHRGTFTCHAQN 1162
Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
+ G +R TL V E + K + Q D +VLEC P + P P W G+ +
Sbjct: 1163 AAGND-TRTVTLTVHTT-PTINAENQEKIALQNDDIVLEC-PAKALPPPVRLWTYEGEKI 1219
Query: 150 LFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
D H + + G LV+Q+ + + G + C N AG +S TL +H KP +I+
Sbjct: 1220 --DSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAG-EDSLSYTLTVHEKPKIISEV 1276
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
VV G ++ CR G P W ++ M + V + G+LR+ D
Sbjct: 1277 PGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLRIYEADKNDI 1336
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTCTATGRPEPTMFW 326
G Y+C N G + ++ V +PP I S + N G+ C P ++ W
Sbjct: 1337 GNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTW 1396
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
G I G Y V + L I D+ C A N AG + +
Sbjct: 1397 FRRG----IAIGTDTKGY----VVESDGTLVIQSASVEDA-TIYTCKASNPAGKAEANLQ 1447
Query: 387 LTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445
+TV S D + P ++T ++ P C P P I+WY + LI +
Sbjct: 1448 VTVIASPDIKDPDVVTQESIKESHPFS----LYCPVFSNPLPQISWYLNDKPLIDDKTSW 1503
Query: 446 VTNDGTLVLKDLDK--SDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
T+D L +DSG Y CVA + G+ S + V P+N
Sbjct: 1504 KTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLN 1549
Score = 120 bits (288), Expect = 8e-27
Identities = 121/472 (25%), Positives = 188/472 (39%), Gaps = 38/472 (8%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E PY ++Q + + TL+C A G+P P I + K G + I+ G +
Sbjct: 2852 ETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--GSTLVI 2909
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
V G Y C A N G RS + +L + E + + GD + LEC
Sbjct: 2910 DNPQKEVE---GRYTCIAENKAG--RSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLEC 2964
Query: 130 LPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
P + ++ W + G+ D ++ D L I A DA Y CIA N AG
Sbjct: 2965 -PIEDTSGVHITWSRQFGKDGQLDMRAQSSS-DKSKLYIMQATPEDADSYSCIAVNDAGG 3022
Query: 189 RESAIATLKIHIKPYLIT---GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
E A+ + ++ P + ++VA T ++ CR G P P++ W
Sbjct: 3023 AE-AVFQVTVNTPPKIFGDSFSTTEIVADT--TLEIPCRTEGIPPPEISWFLDGKPILEM 3079
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
G D SLR+DN+ EG Y+C AEN G Y+ + +PP + ++ + V
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVV 3139
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G C G PEP + W +G P S +T ++ L + +T D
Sbjct: 3140 EGRQTTIRCEVFGNPEPVVNWLKDGE-----PYTSDLLQFSTK----LSYLHLRETTLAD 3190
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
T C A N AG S T T + PP I + + + C P
Sbjct: 3191 G-GTYTCIATNKAGES-----QTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244
Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
P + W G+ + Q + L +++ ++D G Y+C+AS+ G V
Sbjct: 3245 VPYVTWKRNGKEIEQ-------FNPVLHIRNATRADEGKYSCIASNEAGTAV 3289
Score = 118 bits (285), Expect = 2e-26
Identities = 128/483 (26%), Positives = 203/483 (42%), Gaps = 61/483 (12%)
Query: 23 VARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V R + C+ G P P IRW+K G ++ + G L + G DAG
Sbjct: 713 VGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIM----GAKDEDAG 768
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNV 140
Y C N G +++V R +E P + + V L+CL G P P +
Sbjct: 769 AYSCVGENMAGKDVQ---VANLSVGRVPTIIESPHTVRVNIERQVTLQCLAV-GIPPPEI 824
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH- 199
W+K L + R + GNL+I DA+ D G++ CIARN G ++S TL +
Sbjct: 825 EWQKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYG-QQSQSTTLMVTG 883
Query: 200 -IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGR---VKVLDD 254
+ P L P + G +T C V G P P ++W + + P+ +K+
Sbjct: 884 LVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKD----DKPVEEGPTIKIEGG 939
Query: 255 GS-LRLDNVILADEGEYSCEAENSVG--AVSASGYLT-----VYDPP-SINLSPNSVNVE 305
GS LRL DEG+Y+C A + G + + L VY P I P ++
Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999
Query: 306 SGNVA--------------RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
+VA C +G P P + W ++G I P SRD + TA
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRP--ITPN-SRD-FTVTA--- 1052
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L + DK+ S C A N AG + + + + + P+I+ G S+ + +
Sbjct: 1053 -DNTLIVRKADKSYS-GVYTCQATNSAGDNEQKTTIRIMN-----TPMISPGQSSFNMVV 1105
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
+ PC P+P+I W + + + V DG+L + +++++ GT+TC A +
Sbjct: 1106 DDLFTIPCDVYGDPKPVITWLLDDKPFTEG---VVNEDGSLTIPNVNEAHRGTFTCHAQN 1162
Query: 472 RHG 474
G
Sbjct: 1163 AAG 1165
Score = 116 bits (278), Expect = 1e-25
Identities = 125/466 (26%), Positives = 191/466 (40%), Gaps = 28/466 (6%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++TV + TL C + I W G +++T AGG F L + D
Sbjct: 2015 ELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGVQTLAGGRF-LHIVSAKT-DD 2072
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
G Y C TN G A ++ L V V E + +++VL C G P P
Sbjct: 2073 HGSYACTVTNEAGVA-TKTFNLFVQVPPTIVN-EGGEYTVIENNSLVLPC-EVTGKPNPV 2129
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
V W K+G+ + D S L +G I A G Y C+A+N GT E + + I
Sbjct: 2130 VTWTKDGRPV-GDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEISF-DVDII 2187
Query: 200 IKPYLITGPEDVV-AQTGSSVTFQCRVGGDP--LPDVLWRRSAGGGNMPLGRVKVL---D 253
+P + G +++V A G ++ F+C + D ++W R+ ++ ++ +
Sbjct: 2188 TRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSN 2247
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVA 310
D L + NV DEG+YSC +N G S TV PP+I + N VE V
Sbjct: 2248 DRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVT 2307
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
+C ATG+PEP + W +G I ++ + + + + I + D
Sbjct: 2308 -LSCPATGKPEPDITWFKDG-EAIHIENIADIIPNGELNGNQLKITRIKEGD----AGKY 2361
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AGS + V + P I +G PS+ V C P I
Sbjct: 2362 TCEADNSAGSVEQDVNVNVIT----IPKIEKDGIPSDYESQQNERVVISCPVYARPPAKI 2417
Query: 430 AWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
W G+ L + N L L L ++DS YTC+A++ G
Sbjct: 2418 TWLKAGKPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAG 2463
Score = 110 bits (264), Expect = 7e-24
Identities = 114/460 (24%), Positives = 188/460 (40%), Gaps = 45/460 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C SP ++ W++ G+ + +DT ++ + G +++ DA +Y C+A+N
Sbjct: 1382 LKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE---DATIYTCKASNP 1438
Query: 91 YGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
G A A L V V+ +P+ + + L C P +P P + W N +
Sbjct: 1439 AGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYC-PVFSNPLPQISWYLNDK 1494
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT-----RESAIATLKIHIKP 202
L+ D S D L + A+ TD+G Y+C+ARNAAG + I L +
Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESK 1554
Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSLRL 259
Y + V A+ G VT C V G P+P + W G G D +L
Sbjct: 1555 Y----KKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHF 1610
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TATG 318
D+V + EG Y C A++ + L+V P + N + V G +C T
Sbjct: 1611 DSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDN-LEVFLGKDISLSCDLQTE 1669
Query: 319 RPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
+ T F WS+ G+ + D+ + L I D K ++ +C N
Sbjct: 1670 SDDKTTFVWSINGSES--------DRPDNVQIPSDGHRLYITDA-KPENNGKYMCRVTNS 1720
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + + T+T D PP + +NQ L + + C P+P + W +G
Sbjct: 1721 AG----KAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGN 1776
Query: 437 ALIQNHRRNVTNDGTLVLKDLDK--SDSGTYTCVASSRHG 474
+ ++ D +L L ++K S +C A ++ G
Sbjct: 1777 DV----DKSWLFDESLSLLRIEKLTGKSAQISCTAENKAG 1812
Score = 104 bits (249), Expect = 4e-22
Identities = 98/387 (25%), Positives = 144/387 (37%), Gaps = 20/387 (5%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I P +T + +L C G P P I W G + + + A G +
Sbjct: 4139 ITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAE 4198
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R H +Y C A N G A + + V + ++G V++C
Sbjct: 4199 ER-HL---IYECTAKNDAG-ADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES 4253
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
S E + W KNG LL ++ + D + I R +D G Y C A N AG
Sbjct: 4254 ESSEFS--WSKNGVPLL-PSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQK- 4309
Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVL 252
L + + P ++ P V G VT C G P P + W + N +
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT 4369
Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
S+ ++ + G Y+C+AEN V + L V PP + +V+
Sbjct: 4370 KKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFL 4429
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
+C ATG PEP + W + N I + +KY T L I + +D C
Sbjct: 4430 SCNATGIPEPVISWMRDSNIAI----QNNEKYQILG-----TTLAIRNVLPDDD-GFYHC 4479
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPI 399
A + AG KL V DRP PI
Sbjct: 4480 IAKSDAGQKIATRKLIVNKPSDRPAPI 4506
Score = 98.3 bits (234), Expect = 3e-20
Identities = 109/363 (30%), Positives = 152/363 (41%), Gaps = 31/363 (8%)
Query: 6 VTSGEAPYII-EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63
+T E P II E P V V + + CRA G P W K G+ L + + S+
Sbjct: 1264 LTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNL 1323
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQ 121
G L A +D G Y C TN GT++ T HV V L + +
Sbjct: 1324 GTLRIYEAD----KNDIGNYNCVVTNEAGTSQ---MTTHVDVQEPPIILPSTQTNNTAVV 1376
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQC 180
GD V L+C SP +V W + G + D++ ++V+ G LVIQ A DA Y C
Sbjct: 1377 GDRVELKCY-VEASPPASVTWFRRG--IAIGTDTKGYVVESDGTLVIQSASVEDATIYTC 1433
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ----TGSSVTFQCRVGGDPLPDVLWR 236
A N AG E A L++ + DVV Q + C V +PLP + W
Sbjct: 1434 KASNPAGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWY 1490
Query: 237 RSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
+ K DD L + + D G Y C A N+ G S S + V P ++
Sbjct: 1491 LNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNL 1550
Query: 296 NLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH-ATAVFDG 352
+ S V + G C +G P P + W V+G T++ PG KY AT DG
Sbjct: 1551 DESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDG--TVVEPG---KKYKGATLSNDG 1605
Query: 353 VTV 355
+T+
Sbjct: 1606 LTL 1608
Score = 97.5 bits (232), Expect = 5e-20
Identities = 87/342 (25%), Positives = 139/342 (40%), Gaps = 23/342 (6%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IARNAAGTRESAIATLK 197
+YW K G+ ++ G H D I + DAG Y+C I+ N + ++ + T +
Sbjct: 460 IYWVKTGEDII-GGPLFYHNTDTSVWTIPELSLKDAGEYECRVISNNGNYSVKTRVETRE 518
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR-SAGGGNMPLGRVKVLDDGS 256
P I G +V G + C ++ W R A N P + +G+
Sbjct: 519 ---SPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGP-NTERNPTNGT 574
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
L++ +V AD G Y C A N+ G + L + +PPS+ ++P V +C A
Sbjct: 575 LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEA 634
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G P+P + W +G ++ KY V L I D +D T C A++
Sbjct: 635 MGDPKPEVHWYFKGRHL-----LNDYKYQ---VGQDSKFLYIRDATHHD-EGTYECRAMS 685
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEG 435
AG + L + + PP + + + F C I P P I W+ G
Sbjct: 686 QAGQARDTTDLMLAT-----PPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNG 740
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
+ LI+ N+G L + D+G Y+CV + GK V
Sbjct: 741 KDLIKPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDV 782
Score = 93.5 bits (222), Expect = 8e-19
Identities = 106/471 (22%), Positives = 181/471 (38%), Gaps = 34/471 (7%)
Query: 10 EAPYIIEQPLDVT--VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
E P +E + + + P L C+ G+P P + W G +D +S L L
Sbjct: 1734 EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDG----NDVDKSWLFDESLS 1789
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVV 126
LR ++ + C A N GTA SR+ + + F+ E + + + +T+
Sbjct: 1790 LLRIE--KLTGKSAQISCTAENKAGTA-SRDFFIQ-NIAAPTFKNEGDQETIFRESETIT 1845
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L+C P + + W K G L + D+ + +D L I +A + Y C+A N A
Sbjct: 1846 LDC--PVSLGDFQITWMKQGLPLT-ENDA-IFTLDNTRLTILNANRDHEDIYTCVANNTA 1901
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G + S + + + P + + G + C G+P P W G++P
Sbjct: 1902 G-QVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKW--DFNQGDLPK 1958
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNV 304
V V ++ ++ ++NV G Y C A N VG + + V P L+ + + V
Sbjct: 1959 EAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTV 2018
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
C + W+V G P ++ + G L I K
Sbjct: 2019 NLTRSITLECDVDDAIGVGISWTVNGK-----PFLA--ETDGVQTLAGGRFLHIVSA-KT 2070
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D + C+ N AG + L V + PP I N T+ + V PC
Sbjct: 2071 DDHGSYACTVTNEAGVATKTFNLFV-----QVPPTIVNEGGEYTVIENNSLVLPCEVTGK 2125
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
P P++ W +G + V ++G + + + G+Y C+A + G
Sbjct: 2126 PNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVG 2176
Score = 92.7 bits (220), Expect = 1e-18
Identities = 114/453 (25%), Positives = 176/453 (38%), Gaps = 45/453 (9%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
S S W K GV ++ + L + +T SD G Y C A N G A ++
Sbjct: 4253 SESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTR---LSDQGEYSCTAANKAGNA-TQ 4308
Query: 98 NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
L+V V + P ++ +GD V L C G P+P + W K+ + L G
Sbjct: 4309 KTNLNVGVAPKIME-RPRTQVVHKGDQVTLWC-EASGVPQPAITWYKDNELLTNTGVDET 4366
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217
+++ + AG Y C A N + E I L + I P ++ +V
Sbjct: 4367 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDI-DLIVMIPPEVVPERMNVSTNPRQ 4425
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
+V C G P P + W R + + ++L +L + NV+ D+G Y C A++
Sbjct: 4426 TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGT-TLAIRNVLPDDDGFYHCIAKSD 4484
Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
G A+ L V P P + VE C G+P+ T + +I
Sbjct: 4485 AGQKIATRKLIVNKPSD---RPAPIWVE--------CDEKGKPKKTEY--------MIDR 4525
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
G + D D +L D + + +I Y R TV P
Sbjct: 4526 GDTPD--------DNPQLLPWKDVEDSSLNGSIA-----YRCMPGPRSSRTVLLH--AAP 4570
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
I P N T I ++ C+A P P I W +G+ LI++ + + V +
Sbjct: 4571 QFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAYSHLKVTLN- 4627
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
SDSG YTC+A + G S + VD+ I P
Sbjct: 4628 STSDSGEYTCMAQNSVGSSTVSAFINVDNNILP 4660
Score = 89.8 bits (213), Expect = 1e-17
Identities = 124/473 (26%), Positives = 194/473 (41%), Gaps = 62/473 (13%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGL 66
G AP I+E+P V + TL C A G P PAI WYK L+ + + +
Sbjct: 4315 GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSV 4374
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
F + S AGVY C+A N + + + L + ++ E E + + TV
Sbjct: 4375 IFSSIS----PSQAGVYTCKAEN-WVASTEEDIDL-IVMIPPEVVPERMNVSTNPRQTVF 4428
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G PEP + W ++ + + + + + G L I++ D G Y CIA++ A
Sbjct: 4429 LSC-NATGIPEPVISWMRDSNIAIQNNEK--YQILGTTLAIRNVLPDDDGFYHCIAKSDA 4485
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGNM 244
G + IAT K+ ++ P D A + +C G P ++ R N
Sbjct: 4486 GQK---IATRKL-----IVNKPSDRPA----PIWVECDEKGKPKKTEYMIDRGDTPDDNP 4533
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
L K ++D SL N +A Y C + +S + ++ P + P +
Sbjct: 4534 QLLPWKDVEDSSL---NGSIA----YRC-----MPGPRSSRTVLLHAAPQFIVKPKNTTA 4581
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G + C+A G P PT+ W+ +G +I Y V T+N T +
Sbjct: 4582 AIGAIVELRCSAAGPPHPTITWAKDGK--LIEDSKFEIAYSHLKV-------TLNST--S 4630
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAIC 423
DS C A N GSS V + V ++ P P SNQ K++AV C
Sbjct: 4631 DS-GEYTCMAQNSVGSSTVSAFINV-DNNILPTP---KPSSNQ----KNVAVITCYERNQ 4681
Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKD---LDKSDSGTYTCVASSR 472
+ W + G + +N + N+G+LV+ D L + D YTC +R
Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734
Score = 87.4 bits (207), Expect = 5e-17
Identities = 96/349 (27%), Positives = 138/349 (39%), Gaps = 25/349 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I +P + T A L C A G P P I W K G L + D+ I + L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKL-IEDSKFEIAYSHLKVTLN 4627
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
+T SD+G Y C A NS G ++T+ + + L S Q + V+ C
Sbjct: 4628 ST-----SDSGEYTCMAQNSVG-----SSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA---RQTDAGRYQCIARNAAG 187
+ + W+ NG + + +H ++ G+LVI D ++ D Y C RN
Sbjct: 4678 ERNQAYSRGLTWEYNGVPMP-KNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRN--- 4733
Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPL-PDVLWRRSAGGGNM 244
R +I L + P + T + V G SV C V DPL V+W ++ +
Sbjct: 4734 RRRHSIPHLTSAFEGVPEVKT-IDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN-DQKML 4791
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
+ VL + SL L NV DEG Y C A NS+G L VY S + N
Sbjct: 4792 DDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYGGSSRREAYKKENE 4851
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS--RDKYHATAVFD 351
++ T + T T + I P D YH + D
Sbjct: 4852 DASTTTITTTSPTTTTTETPLTTTIIPALITLPAKQYPTDDYHEGSAND 4900
Score = 82.2 bits (194), Expect = 2e-15
Identities = 109/467 (23%), Positives = 178/467 (38%), Gaps = 52/467 (11%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P ++ + ++V+ Q L+C A G P P I W + + + + + + L A
Sbjct: 4410 PEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTL----A 4465
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ D G Y C A + G + AT + V + R P + +EC
Sbjct: 4466 IRNVLPDDDGFYHCIAKSDAG---QKIATRKLIVNKPSDRPAP----------IWVEC-D 4511
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
+G P+ Y G T D L+ + ++D+ + Y+C+ G R S
Sbjct: 4512 EKGKPKKTEYMIDRGDT----PDDNPQLLPWKD--VEDSSLNGSIAYRCMP----GPRSS 4561
Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
T+ +H P I P++ A G+ V +C G P P + W A G +
Sbjct: 4562 R--TVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITW---AKDGKLIEDSKFE 4616
Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
+ L++ +D GEY+C A+NSVG+ + S ++ V + P+S NVA
Sbjct: 4617 IAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSS---NQKNVAV 4673
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD--KNDSRNT 369
TC + + T + G+ K A F L I DT K
Sbjct: 4674 ITCYERNQ-------AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLEL 4726
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP-EPI 428
C N S +TS + P + T + V C P
Sbjct: 4727 YTCKVRNRRRHSIPH----LTSAFEGVPEVKT--IDKVEVNNGDSVVLDCEVTSDPLTTH 4780
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W + ++ + V + +LVL +++K D G Y CVAS+ GK
Sbjct: 4781 VVWTKNDQKMLDDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGK 4827
Score = 77.8 bits (183), Expect = 4e-14
Identities = 79/334 (23%), Positives = 134/334 (40%), Gaps = 20/334 (5%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
D ++ + AP + T+ R + TL+C I W K G+ + + L
Sbjct: 1817 DFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ-ITWMKQGLPLTENDAIFTL 1875
Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L L A R H D +Y C A N+ G S++ + V VL + + + + +
Sbjct: 1876 DNTRLTILNAN--RDHED--IYTCVANNTAGQV-SKDFDVVVQVL-PKIKNAVVTLEINE 1929
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ ++L C G+P P W N L + + + + +V+ + + G Y+C
Sbjct: 1930 GEEIILTC-DAEGNPTPTAKWDFNQGDLPKEA---VFVNNNHTVVVNNVTKYHTGVYKCY 1985
Query: 182 ARNAAGTRESAIATLKIHI--KPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
A N G A+ T+ +H+ KP +G ++ S+T +C V + W
Sbjct: 1986 ATNKVG---QAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042
Query: 238 SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ V+ L G L + + D G Y+C N G + + L V PP+I
Sbjct: 2043 NGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
V N C TG+P P + W+ +G
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG 2136
Score = 76.6 bits (180), Expect = 1e-13
Identities = 120/515 (23%), Positives = 196/515 (38%), Gaps = 46/515 (8%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
+ TL C G P P I W G +V ++ + L V + G Y C
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQE-GNYHC 1623
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKK 144
A + + + ++VL E ++ + G + L C L + W
Sbjct: 1624 VAQSK---GNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSI 1680
Query: 145 NGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
NG D + + DG L I DA+ + G+Y C N+AG E + TL + ++P
Sbjct: 1681 NGSE--SDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTL-TLDV-LEPP 1736
Query: 204 LITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRL 259
+ P Q + + QC+V G+P P V+W+ GN + + + D+ SL
Sbjct: 1737 VFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKID---GN-DVDKSWLFDESLSLLR 1792
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV--ESGNVARFTCTAT 317
+ + SC AEN G S ++ P+ + + ES + +
Sbjct: 1793 IEKLTGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSL 1852
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G + T W +G P D A D T LTI + ++ D + C A N
Sbjct: 1853 GDFQIT--WMKQG-----LPLTEND---AIFTLDN-TRLTILNANR-DHEDIYTCVANNT 1900
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
AG + V + P I N + + C A P P W F +
Sbjct: 1901 AGQVSKDFDVVV-----QVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDF-NQG 1954
Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
+ V N+ T+V+ ++ K +G Y C A+++ G+ V + ++ + F
Sbjct: 1955 DLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKT----INVHVRTKPRFESG 2010
Query: 498 ADVSSLPGPPTKPIT--HNVTDT-SVTLSWSQNNK 529
S L T+ IT +V D V +SW+ N K
Sbjct: 2011 LTESELTVNLTRSITLECDVDDAIGVGISWTVNGK 2045
>AF074901-1|AAC26792.1| 5198|Caenorhabditis elegans hemicentin
precursor protein.
Length = 5198
Score = 161 bits (391), Expect = 3e-39
Identities = 145/510 (28%), Positives = 222/510 (43%), Gaps = 30/510 (5%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
VA +QP + C G P P+I+W K G V D + I+ G + + T AG
Sbjct: 3779 VAVNQPTIMRCAVTGHPFPSIKWLKNGKEVTDDENIRIVEQGQVLQILRTDS---DHAGK 3835
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
+ C A N G + L V ++ ++ A G+T+ L C G+P P + W
Sbjct: 3836 WSCVAENDAGV-KELEMVLDVFT-PPVVSVKSDNPIKALGETITLFC-NASGNPYPQLKW 3892
Query: 143 KKNGQTLLFDG-DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
K G +L+FD D + G L I ++TD G Y C A NAAGT E+++ ++ + +
Sbjct: 3893 AKGG-SLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAGTSEASV-SVDVLVP 3950
Query: 202 PYLITGPEDVVAQ--TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LR 258
P + D+ + S+T QC G P+P + W + + V D + ++
Sbjct: 3951 PEINRDGIDMSPRLPAQQSLTLQCLAQGKPVPQMRWTLNGTALTHSTPGITVASDSTFIQ 4010
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
++NV L+D+G Y+C AEN G+ + + V P I+ + + V G +A C G
Sbjct: 4011 INNVSLSDKGVYTCYAENVAGSDNLMYNVDVVQAPVIS-NGGTKQVIEGELAVIECLVEG 4069
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
P P + W GNR + G+ +Y V DG +LTI + DS +CSA N A
Sbjct: 4070 YPAPQVSWLRNGNR--VETGVQGVRY----VTDG-RMLTIIEARSLDS-GIYLCSATNEA 4121
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL 438
GS+ L V P IIT+ P T S PC P+PII+W G +
Sbjct: 4122 GSAQQAYTLEVLVS----PKIITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDI 4177
Query: 439 IQNHR-RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
+ DGTL ++ ++ Y C A + G V + + P I
Sbjct: 4178 KDGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLE--FPVQTIVAPKISTSGN 4234
Query: 498 ADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
++ G T I + S SWS+N
Sbjct: 4235 RYINGSEGTET-VIKCEIESESSEFSWSKN 4263
Score = 151 bits (367), Expect = 2e-36
Identities = 123/446 (27%), Positives = 189/446 (42%), Gaps = 29/446 (6%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C G+P P I WY G + ++ + A +R S +GVY C+ATNS G
Sbjct: 1022 CVVSGTPPPIITWYLDGRPITPNSRDFTVTADNTLIVRKAD---KSYSGVYTCQATNSAG 1078
Query: 93 TARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFD 152
+ + ++ +S + D + G P+P + W LL D
Sbjct: 1079 DNEQKTT---IRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITW------LLDD 1129
Query: 153 GDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDV 211
+V + G+L I + + G + C A+NAAG ++ TL +H P + ++
Sbjct: 1130 KPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAAG-NDTRTVTLTVHTTPTINAENQEK 1188
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
+A + +C P P LW + L + +DG+L L NV L + G +
Sbjct: 1189 IALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKLENTGVFV 1248
Query: 272 CEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
C+ N G S S LTV++ P I+ P V+V G C ATG PE W+ G
Sbjct: 1249 CQVSNLAGEDSLSYTLTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNG 1308
Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVT 390
I M K+ D + L I + DKND N C N AG+S ++T
Sbjct: 1309 ----IDLKMDEKKFSV----DNLGTLRIYEADKNDIGN-YNCVVTNEAGTS----QMTTH 1355
Query: 391 SDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-ND 449
D PP I+ + +N T + C +P + W+ G A+ + + V +D
Sbjct: 1356 VDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTWFRRGIAIGTDTKGYVVESD 1415
Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGK 475
GTLV++ D+ YTC AS+ GK
Sbjct: 1416 GTLVIQSASVEDATIYTCKASNPAGK 1441
Score = 141 bits (342), Expect = 2e-33
Identities = 130/510 (25%), Positives = 225/510 (44%), Gaps = 45/510 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
++C+ G P P + W + G + I + +R +D G Y C A+N
Sbjct: 3236 VHCQVTGRPVPYVTWKRNG--------KEIEQFNPVLHIR---NATRADEGKYSCIASNE 3284
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLL 150
GTA + L + F + +G++ +EC G P+P + W K G+
Sbjct: 3285 AGTAVAD--FLIDVFTKPTFETHETTFNIVEGESAKIECKID-GHPKPTISWLKGGRP-- 3339
Query: 151 FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI-TGPE 209
F+ D+ + G L+I A++ D G Y C+A N+ G E + ++ KPY+ T +
Sbjct: 3340 FNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFK-VNVYTKPYIDETIDQ 3398
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL-GRVKVLDDGSLRLDNVILADEG 268
A G + +C V G+P P V W+R G +P R ++++ L++++V D G
Sbjct: 3399 TPKAVAGGEIILKCPVLGNPTPTVTWKR--GDDAVPNDSRHTIVNNYDLKINSVTTEDAG 3456
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPS-INLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
+YSC A N G ++ V P+ + N V + C T RP P++ W
Sbjct: 3457 QYSCIAVNEAGNLTTHYAAEVIGKPTFVRKGGNLYEVIENDTITMDCGVTSRPLPSISW- 3515
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
G++ + D+Y + DG + +TIN +D +C A N AG+S + L
Sbjct: 3516 FRGDKPVYL----YDRYSISP--DG-SHITINKAKLSDG-GKYICRASNEAGTSDIDLIL 3567
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVF-PCTAICTPEPIIAWYFEGEALIQNHRRNV 446
+ PP I + L I + ++ C P+P + W G + R +
Sbjct: 3568 KILV----PPKIDKSNIIGNPLAIVARTIYLECPISGIPQPDVIWTKNGMDINMTDSRVI 3623
Query: 447 T--NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH-----FFRAAD 499
N+ T ++++ +D G YTC A++R GK +L V SP +IH R D
Sbjct: 3624 LAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSPPEFDIHGTQPTIKREGD 3683
Query: 500 VSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
+L P + ++ D + +SW+++++
Sbjct: 3684 TITLTCP--IKLAEDIADQVMDVSWTKDSR 3711
Score = 138 bits (334), Expect = 2e-32
Identities = 122/451 (27%), Positives = 185/451 (41%), Gaps = 31/451 (6%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
Q TL C A G P P +RW G + T I A F++ + + SD GVY C
Sbjct: 3968 QSLTLQCLAQGKPVPQMRWTLNGTALTHSTP-GITVASDSTFIQINNVSL-SDKGVYTCY 4025
Query: 87 ATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
A N G S N +V V++ +KQ +G+ V+ECL G P P V W +NG
Sbjct: 4026 AENVAG---SDNLMYNVDVVQAPVISNGGTKQVIEGELAVIECLV-EGYPAPQVSWLRNG 4081
Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
+ ++ DG L I +AR D+G Y C A N AG+ + A TL++ + P +IT
Sbjct: 4082 NRVETGVQGVRYVTDGRMLTIIEARSLDSGIYLCSATNEAGSAQQAY-TLEVLVSPKIIT 4140
Query: 207 G-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
P + +GS + C V G P P + W + + DG+L ++ A
Sbjct: 4141 STPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEK---A 4197
Query: 266 DEGE--YSCEAENSVGAVSASGYLTVYDPPSINLSPNS-VNVESGNVARFTCTATGRPEP 322
+E Y C A+N GA + + P I+ S N +N G C
Sbjct: 4198 EERHLIYECTAKNDAGADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIESE-SS 4256
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
WS G P + + + + + +L+ +D+ + C+A N AG++
Sbjct: 4257 EFSWSKNG-----VPLLPSNNLIFSEDYKLIKILSTRLSDQGE----YSCTAANKAGNAT 4307
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN- 441
+ L V P I P Q + C A P+P I WY + E L
Sbjct: 4308 QKTNLNV-----GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTG 4362
Query: 442 -HRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
T +++ + S +G YTC A +
Sbjct: 4363 VDETATTKKKSVIFSSISPSQAGVYTCKAEN 4393
Score = 137 bits (331), Expect = 5e-32
Identities = 121/463 (26%), Positives = 195/463 (42%), Gaps = 28/463 (6%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + C G P+P + W + G V + G L R D+G+Y C AT
Sbjct: 4061 AVIECLVEGYPAPQVSWLRNGNRVETGVQGVRYVTDGRM-LTIIEAR-SLDSGIYLCSAT 4118
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
N G+A+ TL V V + P + G L C RG P+P + W NG
Sbjct: 4119 NEAGSAQQAY-TLEVLVSPKIITSTPGVLTPSSGSKFSLPCAV-RGYPDPIISWTLNGND 4176
Query: 149 LLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYLIT 206
+ DG++ + G L I+ A + Y+C A+N AG T E + T+ + P + T
Sbjct: 4177 IK-DGENGHTIGADGTLHIEKAEERHL-IYECTAKNDAGADTLEFPVQTI---VAPKIST 4231
Query: 207 -GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVIL 264
G + G+ +C + + + W ++ G +P + +D L ++ + L
Sbjct: 4232 SGNRYINGSEGTETVIKCEIESES-SEFSWSKN-GVPLLPSNNLIFSEDYKLIKILSTRL 4289
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
+D+GEYSC A N G + L V P I P + V G+ C A+G P+P +
Sbjct: 4290 SDQGEYSCTAANKAGNATQKTNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAI 4349
Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
W + N + G+ AT V +I+ + C A N+ S+
Sbjct: 4350 TW-YKDNELLTNTGVDET---ATTKKKSVIFSSISPSQAG----VYTCKAENWVASTEED 4401
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
L V PP ++ + T P + C A PEP+I+W + IQN+ +
Sbjct: 4402 IDLIVMI----PPEVVPERMNVSTNP-RQTVFLSCNATGIPEPVISWMRDSNIAIQNNEK 4456
Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
TL ++++ D G Y C+A S G+ + + L+V+ P
Sbjct: 4457 YQILGTTLAIRNVLPDDDGFYHCIAKSDAGQKIATRKLIVNKP 4499
Score = 136 bits (329), Expect = 9e-32
Identities = 126/472 (26%), Positives = 200/472 (42%), Gaps = 23/472 (4%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
V + E+P I +V+V + A L+C + IRW + G V + + P G
Sbjct: 514 VETRESPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGPNTERNPTNG 573
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
+ H +DAGVY C A N+ G + +R L + + ++ P+ + V
Sbjct: 574 TLKI---HHVTRADAGVYECMARNAGGMS-TRKMRLDI-MEPPSVKVTPQDVYFNMREGV 628
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C G P+P V+W G+ LL D ++ D L I+DA D G Y+C A +
Sbjct: 629 NLSC-EAMGDPKPEVHWYFKGRHLLNDYKYQVGQ-DSKFLYIRDATHHDEGTYECRAMSQ 686
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWRRSAGGGNM 244
AG L + P + ++ G V+F+C+ + G P P + W ++
Sbjct: 687 AGQARDT-TDLMLATPPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIK 745
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
P +K+ ++G L + D G YSC EN G L+V P+I SP++V V
Sbjct: 746 PDDYIKI-NEGQLHIMGAKDEDAGAYSCVGENMAGKDVQVANLSVGRVPTIIESPHTVRV 804
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
C A G P P + W +GN ++ ++ +Y T + DG L I D
Sbjct: 805 NIERQVTLQCLAVGIPPPEIEWQ-KGN--VLLATLNNPRY--TQLADG--NLLITDAQIE 857
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC- 423
D + C A N G L VT P++ + P + L C +
Sbjct: 858 D-QGQFTCIARNTYGQQSQSTTLMVTG---LVSPVLGHVPPEEQLIEGQDLTLSCVVVLG 913
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHG 474
TP+P I W + + + + + G+L+ L+ + D G YTC+A S G
Sbjct: 914 TPKPSIVWIKDDKPVEEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVSPAG 965
Score = 135 bits (327), Expect = 2e-31
Identities = 129/474 (27%), Positives = 202/474 (42%), Gaps = 28/474 (5%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
++++ + T H TL+C A G P P I W+K G + + I+P G L +
Sbjct: 2291 MLDKDKNKTAVEHSTVTLSCPATGKPEPDITWFKDGEAIHIENIADIIPNGELNGNQLKI 2350
Query: 74 GRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
R+ DAG Y CEA NS G+ + + + E P +S Q + VV+ C P
Sbjct: 2351 TRIKEGDAGKYTCEADNSAGSVEQDVNVNVITIPKIEKDGIPSDYESQQNERVVISC-PV 2409
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT--RE 190
P + W K G+ L D + +G L + R+TD+ +Y CIA N AGT R+
Sbjct: 2410 YARPPAKITWLKAGKPLQSDKFVKTS-ANGQKLYLFKLRETDSSKYTCIATNEAGTDKRD 2468
Query: 191 SAIATL--KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
++ L +P ++ + +G+ T C G P P + W + G P R
Sbjct: 2469 FKVSMLVAPSFDEPNIV---RRITVNSGNPSTLHCPAKGSPSPTITWLKD-GNAIEPNDR 2524
Query: 249 VKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN-LSPNSVNVES 306
D G L++ +D+G Y+C A NSVG+ L V PP I+ +V V
Sbjct: 2525 YVFFDAGRQLQISKTEGSDQGRYTCIATNSVGSDDLENTLEVIIPPVIDGERREAVAVIE 2584
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G + C + + W +G TI + D + + ++ K+DS
Sbjct: 2585 GFSSELFCDSNS-TGVDVEWQKDG-LTINQDTLRGDSF--IQIPSSGKKMSFLSARKSDS 2640
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN---QTLPIKSMAVFPCTAIC 423
C N AG + KL + +D PP I++ S+ QT+ C
Sbjct: 2641 -GRYTCIVRNPAGEA---RKLFDFAVND--PPSISDELSSANIQTIVPYYPVEINCVVSG 2694
Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDG-TLVLKDLDKSDSGTYTCVASSRHGK 475
+P P + W F+ + L + +TN+G TL + +GTYTC A + GK
Sbjct: 2695 SPHPKVYWLFDDKPLEPDSAAYELTNNGETLKIVRSQVEHAGTYTCEAQNNVGK 2748
Score = 134 bits (323), Expect = 5e-31
Identities = 135/505 (26%), Positives = 215/505 (42%), Gaps = 57/505 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGGL 66
G P IIE P V V + TL C A G P P I W KG VL+ +++ + L G L
Sbjct: 790 GRVPTIIESPHTVRVNIERQVTLQCLAVGIPPPEIEWQKGNVLLATLNNPRYTQLADGNL 849
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTV 125
T ++ D G + C A N+YG +S++ TL V ++ P +Q +G +
Sbjct: 850 LI---TDAQI-EDQGQFTCIARNTYG-QQSQSTTLMVTGLVSPVLGHVPPEEQLIEGQDL 904
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARN 184
L C+ G+P+P++ W K+ + + + + + GG+L+ ++ D G+Y CIA +
Sbjct: 905 TLSCVVVLGTPKPSIVWIKDDKPV--EEGPTIKIEGGGSLLRLRGGNPKDEGKYTCIAVS 962
Query: 185 AAGTRESAIATLKIHIKPYLITGPED-----------------VVAQT-----GSSVTFQ 222
AG I +++ KP + PE VV T G
Sbjct: 963 PAGNSTLHI-NVQLIKKPEFVYKPEGGIVFKPTISGMDEKHVAVVNSTHDVLDGEGFAIP 1021
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAENSVGAV 281
C V G P P + W G P R V D +L + + G Y+C+A NS G
Sbjct: 1022 CVVSGTPPPIITWYLD-GRPITPNSRDFTVTADNTLIVRKADKSYSGVYTCQATNSAGDN 1080
Query: 282 SASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
+ + + P I+ +S N+ ++ C G P+P + W ++
Sbjct: 1081 EQKTTIRIMNTPMISPGQSSFNMVVDDLFTIPCDVYGDPKPVITWLLD------------ 1128
Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
DK V + LTI + ++ R T C A N AG+ TVT P I
Sbjct: 1129 DKPFTEGVVNEDGSLTIPNVNE-AHRGTFTCHAQNAAGND----TRTVTLTVHTTPTI-- 1181
Query: 402 NGPSNQTLPIKS-MAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDLDK 459
N + + + +++ V C A P P+ W +EGE + Q + DG LVL+++
Sbjct: 1182 NAENQEKIALQNDDIVLECPAKALPPPVRLWTYEGEKIDSQLIPHTIREDGALVLQNVKL 1241
Query: 460 SDSGTYTCVASSRHGKYVWSGALLV 484
++G + C S+ G+ S L V
Sbjct: 1242 ENTGVFVCQVSNLAGEDSLSYTLTV 1266
Score = 133 bits (322), Expect = 6e-31
Identities = 139/501 (27%), Positives = 212/501 (42%), Gaps = 65/501 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT +P + P + + Q TL+C G+P P+I W K V I G
Sbjct: 881 VTGLVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKDDKPVEEGPTIKIEGGG 940
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVL---REEFRLEPES----- 116
L LR + + D G Y C A + G N+TLH+ V + EF +PE
Sbjct: 941 SLLRLRGGNPK---DEGKYTCIAVSPAG-----NSTLHINVQLIKKPEFVYKPEGGIVFK 992
Query: 117 --------KQSA---------QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL 159
K A G+ + C+ G+P P + W +G+ + +SR
Sbjct: 993 PTISGMDEKHVAVVNSTHDVLDGEGFAIPCVVS-GTPPPIITWYLDGRPIT--PNSRDFT 1049
Query: 160 VDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSS 218
V N L+++ A ++ +G Y C A N+AG E T++I P + G
Sbjct: 1050 VTADNTLIVRKADKSYSGVYTCQATNSAGDNEQK-TTIRIMNTPMISPGQSSFNMVVDDL 1108
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSV 278
T C V GDP P + W + P V +DGSL + NV A G ++C A+N+
Sbjct: 1109 FTIPCDVYGDPKPVITWLLD----DKPFTEGVVNEDGSLTIPNVNEAHRGTFTCHAQNAA 1164
Query: 279 GAVSASGYLTVYDPPSINL-SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR--TII 335
G + + LTV+ P+IN + + +++ ++ C A P P W+ EG + + +
Sbjct: 1165 GNDTRTVTLTVHTTPTINAENQEKIALQNDDIV-LECPAKALPPPVRLWTYEGEKIDSQL 1223
Query: 336 FPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR 395
P R+ DG VL K ++ VC N AG + LTV
Sbjct: 1224 IPHTIRE--------DGALVL---QNVKLENTGVFVCQVSNLAGEDSLSYTLTV----HE 1268
Query: 396 PPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR-NVTNDGTLV 453
P II+ P + +K + PC A PE I W G L + ++ +V N GTL
Sbjct: 1269 KPKIISEVPGVVDV-VKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLR 1327
Query: 454 LKDLDKSDSGTYTCVASSRHG 474
+ + DK+D G Y CV ++ G
Sbjct: 1328 IYEADKNDIGNYNCVVTNEAG 1348
Score = 133 bits (321), Expect = 8e-31
Identities = 129/477 (27%), Positives = 195/477 (40%), Gaps = 40/477 (8%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
D YV E P ++ + V + T+ C G+P P + W K G SD +
Sbjct: 3118 DTYVEISEPPRVVMASEVMRVVEGRQTTIRCEVFGNPEPVVNWLKDGEPYTSDLLQFSTK 3177
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSA 120
L LR T +D G Y C ATN G +++ T V VL R+E E + Q
Sbjct: 3178 LSYL-HLRET---TLADGGTYTCIATNKAGESQT---TTDVEVLVPP-RIEDEERVLQGK 3229
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
+G+T ++ C G P P V WK+NG+ + + + V L I++A + D G+Y C
Sbjct: 3230 EGNTYMVHC-QVTGRPVPYVTWKRNGKEI-----EQFNPV----LHIRNATRADEGKYSC 3279
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
IA N AGT A + + KP T G S +C++ G P P + W + G
Sbjct: 3280 IASNEAGT-AVADFLIDVFTKPTFETHETTFNIVEGESAKIECKIDGHPKPTISWLK--G 3336
Query: 241 GGNMPLGRVKVLDDG-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS- 298
G + + + G +L + D G Y+C A NS G + VY P I+ +
Sbjct: 3337 GRPFNMDNIILSPRGDTLMILKAQRFDGGLYTCVATNSYGDSEQDFKVNVYTKPYIDETI 3396
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
+ +G C G P PT+ W G+ + P SR + +D L I
Sbjct: 3397 DQTPKAVAGGEIILKCPVLGNPTPTVTWK-RGDDAV--PNDSR--HTIVNNYD----LKI 3447
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N D+ C AVN AG+ V P + G + +
Sbjct: 3448 NSVTTEDA-GQYSCIAVNEAGNLTTHYAAEVIG----KPTFVRKGGNLYEVIENDTITMD 3502
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRHG 474
C P P I+W+ + + R +++ DG+ + + SD G Y C AS+ G
Sbjct: 3503 CGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAKLSDGGKYICRASNEAG 3559
Score = 128 bits (310), Expect = 2e-29
Identities = 129/484 (26%), Positives = 191/484 (39%), Gaps = 35/484 (7%)
Query: 23 VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGV 82
V + T++C P P+I W++G V SI P G + SD G
Sbjct: 3493 VIENDTITMDCGVTSRPLPSISWFRGDKPVYLYDRYSISPDGSHITINKAK---LSDGGK 3549
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-QGDTVVLECLPPRGSPEPNVY 141
Y C A+N GT+ + L + V + + A T+ LEC P G P+P+V
Sbjct: 3550 YICRASNEAGTS-DIDLILKILVPPKIDKSNIIGNPLAIVARTIYLEC-PISGIPQPDVI 3607
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
W KNG + DSR+ L I++ + TD GRY C A N G + +
Sbjct: 3608 WTKNGMDINMT-DSRVILAQNNETFGIENVQVTDQGRYTCTATNRGGKASHDFSLDVLSP 3666
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVG-----GDPLPDVLWRRSAGGGNMPL-GRVKVLDD 254
+ I G + + + G ++T C + D + DV W + + + L V + DD
Sbjct: 3667 PEFDIHGTQPTIKREGDTITLTCPIKLAEDIADQVMDVSWTKDSRALDGDLTDNVDISDD 3726
Query: 255 G-SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV--NVESGNVAR 311
G L + L + G Y+C A N G S + + PP I++S N V V
Sbjct: 3727 GRKLTISQASLENAGLYTCIALNRAGEASLEFKVEILSPPVIDISRNDVQPQVAVNQPTI 3786
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIV 371
C TG P P++ W G D + V G VL I TD +D
Sbjct: 3787 MRCAVTGHPFPSIKWLKNGKEV-------TDDENIRIVEQG-QVLQILRTD-SDHAGKWS 3837
Query: 372 CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW 431
C A N AG + L V + PP+++ N + C A P P + W
Sbjct: 3838 CVAENDAGVKELEMVLDVFT-----PPVVSVKSDNPIKALGETITLFCNASGNPYPQLKW 3892
Query: 432 YFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
G + + R L + L K+D G YTC A + G ++ VD +
Sbjct: 3893 AKGGSLIFDSPDGARISLKGARLDIPHLKKTDVGDYTCQALNAAG--TSEASVSVDVLVP 3950
Query: 490 PNIH 493
P I+
Sbjct: 3951 PEIN 3954
Score = 124 bits (299), Expect = 4e-28
Identities = 109/455 (23%), Positives = 187/455 (41%), Gaps = 20/455 (4%)
Query: 22 TVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
T+ + P +NC GSP P + W + D+ L G L+ +V AG
Sbjct: 2679 TIVPYYPVEINCVVSGSPHPKVYWLFDDKPLEPDSAAYELTNNGET-LKIVRSQVEH-AG 2736
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY 141
Y CEA N+ G AR ++ + V F E E + GDT++L C P +VY
Sbjct: 2737 TYTCEAQNNVGKAR-KDFLVRVTA-PPHFEKEREEVVARVGDTMLLTCNAESSVPLSSVY 2794
Query: 142 WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK 201
W + +++ + + + L + + + D G Y C A N AG + + I
Sbjct: 2795 WHAHDESVQNGVITSKYAANEKTLNVTNIQLDDEGFYYCTAVNEAGITKKFFKLIVIE-T 2853
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
PY + + G +T C G P P +L+ + N V ++ +L +DN
Sbjct: 2854 PYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLN-ESDEVDII-GSTLVIDN 2911
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
EG Y+C AEN G + V PP ++ +V V++G+ C
Sbjct: 2912 PQKEVEGRYTCIAENKAGRSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLECPIEDTSG 2971
Query: 322 PTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSS 381
+ WS + + ++ + ++ + T D D + C AVN AG +
Sbjct: 2972 VHITWSRQFGKDGQLDMRAQSSSDKSKLY--IMQATPEDAD------SYSCIAVNDAGGA 3023
Query: 382 FVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
++TV + PP I + S + + PC P P I+W+ +G+ +++
Sbjct: 3024 EAVFQVTVNT----PPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEM 3079
Query: 442 HRRNV-TNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
D +L + ++ + G YTCVA ++ G+
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGR 3114
Score = 123 bits (297), Expect = 7e-28
Identities = 115/417 (27%), Positives = 170/417 (40%), Gaps = 27/417 (6%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEP 138
DAG Y C ++ G + E F + S G+ L C R + E
Sbjct: 493 DAGEYECRVISNNGNYSVKTRVETRESPPEIFGVRNVSVPL--GEAAFLHC-STRSAGEV 549
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
+ W + G T+ F+G + G L I + DAG Y+C+ARNA G + L I
Sbjct: 550 EIRWTRYGATV-FNGPNTERNPTNGTLKIHHVTRADAGVYECMARNAGGMSTRKMR-LDI 607
Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-L 257
P + P+DV V C GDP P+V W G + + +V D L
Sbjct: 608 MEPPSVKVTPQDVYFNMREGVNLSCEAMGDPKPEVHWYFK-GRHLLNDYKYQVGQDSKFL 666
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TA 316
+ + DEG Y C A + G + L + PP + + N + V G+ F C T
Sbjct: 667 YIRDATHHDEGTYECRAMSQAGQARDTTDLMLATPPKVEIIQNKMMVGRGDRVSFECKTI 726
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G+P P + W G + +I P D Y + +G L I K++ C N
Sbjct: 727 RGKPHPKIRWFKNG-KDLIKP----DDY--IKINEGQ--LHIMGA-KDEDAGAYSCVGEN 776
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG L+V R P II + P + I+ C A+ P P I W +G
Sbjct: 777 MAGKDVQVANLSV----GRVPTIIES-PHTVRVNIERQVTLQCLAVGIPPPEIEWQ-KGN 830
Query: 437 ALI---QNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
L+ N R DG L++ D D G +TC+A + +G+ S L+V ++P
Sbjct: 831 VLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYGQQSQSTTLMVTGLVSP 887
Score = 121 bits (292), Expect = 3e-27
Identities = 109/470 (23%), Positives = 184/470 (39%), Gaps = 32/470 (6%)
Query: 6 VTSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
VT P I T + + CR G P P I W+ G ++ +
Sbjct: 3029 VTVNTPPKIFGDSFSTTEIVADTTLEIPCRTEGIPPPEISWFLDGKPILEMP--GVTYKQ 3086
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
G LR + + + + G Y C A N G A ++ + ++ + E + +G
Sbjct: 3087 GDLSLRIDNIKPNQE-GRYTCVAENKAGRAE-QDTYVEISE-PPRVVMASEVMRVVEGRQ 3143
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ C G+PEP V W K+G+ + D L +++ D G Y CIA N
Sbjct: 3144 TTIRC-EVFGNPEPVVNWLKDGEP--YTSDLLQFSTKLSYLHLRETTLADGGTYTCIATN 3200
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
AG ++ +++ + P + + + G++ C+V G P+P V W+R+
Sbjct: 3201 KAGESQTT-TDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRPVPYVTWKRN------ 3253
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
G+ + L + N ADEG+YSC A N G A + V+ P+ + N+
Sbjct: 3254 --GKEIEQFNPVLHIRNATRADEGKYSCIASNEAGTAVADFLIDVFTKPTFETHETTFNI 3311
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G A+ C G P+PT+ W ++G R + D + D + +L D
Sbjct: 3312 VEGESAKIECKIDGHPKPTISW-LKGGRP-----FNMDNIILSPRGDTLMILKAQRFD-- 3363
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
C A N G S K+ V + P I + C +
Sbjct: 3364 --GGLYTCVATNSYGDSEQDFKVNVYT----KPYIDETIDQTPKAVAGGEIILKCPVLGN 3417
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
P P + W +A+ + R + N+ L + + D+G Y+C+A + G
Sbjct: 3418 PTPTVTWKRGDDAVPNDSRHTIVNNYDLKINSVTTEDAGQYSCIAVNEAG 3467
Score = 120 bits (288), Expect = 8e-27
Identities = 121/466 (25%), Positives = 184/466 (39%), Gaps = 32/466 (6%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
T+ C G P P I W +L ++ G + + + G + C A N
Sbjct: 1110 TIPCDVYGDPKPVITW----LLDDKPFTEGVVNEDGSLTIPNVN---EAHRGTFTCHAQN 1162
Query: 90 SYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTL 149
+ G +R TL V E + K + Q D +VLEC P + P P W G+ +
Sbjct: 1163 AAGND-TRTVTLTVHTT-PTINAENQEKIALQNDDIVLEC-PAKALPPPVRLWTYEGEKI 1219
Query: 150 LFDGDSRMHLV-DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP 208
D H + + G LV+Q+ + + G + C N AG +S TL +H KP +I+
Sbjct: 1220 --DSQLIPHTIREDGALVLQNVKLENTGVFVCQVSNLAG-EDSLSYTLTVHEKPKIISEV 1276
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
VV G ++ CR G P W ++ M + V + G+LR+ D
Sbjct: 1277 PGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNLGTLRIYEADKNDI 1336
Query: 268 GEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTCTATGRPEPTMFW 326
G Y+C N G + ++ V +PP I S + N G+ C P ++ W
Sbjct: 1337 GNYNCVVTNEAGTSQMTTHVDVQEPPIILPSTQTNNTAVVGDRVELKCYVEASPPASVTW 1396
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
G I G Y V + L I D+ C A N AG + +
Sbjct: 1397 FRRG----IAIGTDTKGY----VVESDGTLVIQSASVEDA-TIYTCKASNPAGKAEANLQ 1447
Query: 387 LTV-TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRN 445
+TV S D + P ++T ++ P C P P I+WY + LI +
Sbjct: 1448 VTVIASPDIKDPDVVTQESIKESHPFS----LYCPVFSNPLPQISWYLNDKPLIDDKTSW 1503
Query: 446 VTNDGTLVLKDLDK--SDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
T+D L +DSG Y CVA + G+ S + V P+N
Sbjct: 1504 KTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLN 1549
Score = 120 bits (288), Expect = 8e-27
Identities = 121/472 (25%), Positives = 188/472 (39%), Gaps = 38/472 (8%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E PY ++Q + + TL+C A G+P P I + K G + I+ G +
Sbjct: 2852 ETPYFLDQQKLYPIILGKRLTLDCSATGTPPPTILFMKDGKRLNESDEVDII--GSTLVI 2909
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
V G Y C A N G RS + +L + E + + GD + LEC
Sbjct: 2910 DNPQKEVE---GRYTCIAENKAG--RSEKDMMVEVLLPPKLSKEWINVEVQAGDPLTLEC 2964
Query: 130 LPPRGSPEPNVYWKKN-GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
P + ++ W + G+ D ++ D L I A DA Y CIA N AG
Sbjct: 2965 -PIEDTSGVHITWSRQFGKDGQLDMRAQSSS-DKSKLYIMQATPEDADSYSCIAVNDAGG 3022
Query: 189 RESAIATLKIHIKPYLIT---GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP 245
E A+ + ++ P + ++VA T ++ CR G P P++ W
Sbjct: 3023 AE-AVFQVTVNTPPKIFGDSFSTTEIVADT--TLEIPCRTEGIPPPEISWFLDGKPILEM 3079
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
G D SLR+DN+ EG Y+C AEN G Y+ + +PP + ++ + V
Sbjct: 3080 PGVTYKQGDLSLRIDNIKPNQEGRYTCVAENKAGRAEQDTYVEISEPPRVVMASEVMRVV 3139
Query: 306 SGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
G C G PEP + W +G P S +T ++ L + +T D
Sbjct: 3140 EGRQTTIRCEVFGNPEPVVNWLKDGE-----PYTSDLLQFSTK----LSYLHLRETTLAD 3190
Query: 366 SRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
T C A N AG S T T + PP I + + + C P
Sbjct: 3191 G-GTYTCIATNKAGES-----QTTTDVEVLVPPRIEDEERVLQGKEGNTYMVHCQVTGRP 3244
Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
P + W G+ + Q + L +++ ++D G Y+C+AS+ G V
Sbjct: 3245 VPYVTWKRNGKEIEQ-------FNPVLHIRNATRADEGKYSCIASNEAGTAV 3289
Score = 118 bits (285), Expect = 2e-26
Identities = 128/483 (26%), Positives = 203/483 (42%), Gaps = 61/483 (12%)
Query: 23 VARHQPATLNCRA-GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAG 81
V R + C+ G P P IRW+K G ++ + G L + G DAG
Sbjct: 713 VGRGDRVSFECKTIRGKPHPKIRWFKNGKDLIKPDDYIKINEGQLHIM----GAKDEDAG 768
Query: 82 VYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGDTVVLECLPPRGSPEPNV 140
Y C N G +++V R +E P + + V L+CL G P P +
Sbjct: 769 AYSCVGENMAGKDVQ---VANLSVGRVPTIIESPHTVRVNIERQVTLQCLAV-GIPPPEI 824
Query: 141 YWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH- 199
W+K L + R + GNL+I DA+ D G++ CIARN G ++S TL +
Sbjct: 825 EWQKGNVLLATLNNPRYTQLADGNLLITDAQIEDQGQFTCIARNTYG-QQSQSTTLMVTG 883
Query: 200 -IKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGR---VKVLDD 254
+ P L P + G +T C V G P P ++W + + P+ +K+
Sbjct: 884 LVSPVLGHVPPEEQLIEGQDLTLSCVVVLGTPKPSIVWIKD----DKPVEEGPTIKIEGG 939
Query: 255 GS-LRLDNVILADEGEYSCEAENSVG--AVSASGYLT-----VYDPP-SINLSPNSVNVE 305
GS LRL DEG+Y+C A + G + + L VY P I P ++
Sbjct: 940 GSLLRLRGGNPKDEGKYTCIAVSPAGNSTLHINVQLIKKPEFVYKPEGGIVFKPTISGMD 999
Query: 306 SGNVA--------------RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
+VA C +G P P + W ++G I P SRD + TA
Sbjct: 1000 EKHVAVVNSTHDVLDGEGFAIPCVVSGTPPPIITWYLDGRP--ITPN-SRD-FTVTA--- 1052
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
L + DK+ S C A N AG + + + + + P+I+ G S+ + +
Sbjct: 1053 -DNTLIVRKADKSYS-GVYTCQATNSAGDNEQKTTIRIMN-----TPMISPGQSSFNMVV 1105
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
+ PC P+P+I W + + + V DG+L + +++++ GT+TC A +
Sbjct: 1106 DDLFTIPCDVYGDPKPVITWLLDDKPFTEG---VVNEDGSLTIPNVNEAHRGTFTCHAQN 1162
Query: 472 RHG 474
G
Sbjct: 1163 AAG 1165
Score = 116 bits (278), Expect = 1e-25
Identities = 125/466 (26%), Positives = 191/466 (40%), Gaps = 28/466 (6%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++TV + TL C + I W G +++T AGG F L + D
Sbjct: 2015 ELTVNLTRSITLECDVDDAIGVGISWTVNGKPFLAETDGVQTLAGGRF-LHIVSAKT-DD 2072
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPN 139
G Y C TN G A ++ L V V E + +++VL C G P P
Sbjct: 2073 HGSYACTVTNEAGVA-TKTFNLFVQVPPTIVN-EGGEYTVIENNSLVLPC-EVTGKPNPV 2129
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH 199
V W K+G+ + D S L +G I A G Y C+A+N GT E + + I
Sbjct: 2130 VTWTKDGRPV-GDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVGTAEISF-DVDII 2187
Query: 200 IKPYLITGPEDVV-AQTGSSVTFQCRVGGDP--LPDVLWRRSAGGGNMPLGRVKVL---D 253
+P + G +++V A G ++ F+C + D ++W R+ ++ ++ +
Sbjct: 2188 TRPMIQKGIKNIVTAIKGGALPFKCPIDDDKNFKGQIIWLRNYQPIDLEAEDARITRLSN 2247
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGNVA 310
D L + NV DEG+YSC +N G S TV PP+I + N VE V
Sbjct: 2248 DRRLTILNVTENDEGQYSCRVKNDAGENSFDFKATVLVPPTIIMLDKDKNKTAVEHSTVT 2307
Query: 311 RFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
+C ATG+PEP + W +G I ++ + + + + I + D
Sbjct: 2308 -LSCPATGKPEPDITWFKDG-EAIHIENIADIIPNGELNGNQLKITRIKEGD----AGKY 2361
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNG-PSNQTLPIKSMAVFPCTAICTPEPII 429
C A N AGS + V + P I +G PS+ V C P I
Sbjct: 2362 TCEADNSAGSVEQDVNVNVIT----IPKIEKDGIPSDYESQQNERVVISCPVYARPPAKI 2417
Query: 430 AWYFEGEAL-IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
W G+ L + N L L L ++DS YTC+A++ G
Sbjct: 2418 TWLKAGKPLQSDKFVKTSANGQKLYLFKLRETDSSKYTCIATNEAG 2463
Score = 110 bits (264), Expect = 7e-24
Identities = 114/460 (24%), Positives = 188/460 (40%), Gaps = 45/460 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L C SP ++ W++ G+ + +DT ++ + G +++ DA +Y C+A+N
Sbjct: 1382 LKCYVEASPPASVTWFRRGIAIGTDTKGYVVESDGTLVIQSASVE---DATIYTCKASNP 1438
Query: 91 YGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
G A A L V V+ +P+ + + L C P +P P + W N +
Sbjct: 1439 AGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYC-PVFSNPLPQISWYLNDK 1494
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT-----RESAIATLKIHIKP 202
L+ D S D L + A+ TD+G Y+C+ARNAAG + I L +
Sbjct: 1495 PLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNLDESK 1554
Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSLRL 259
Y + V A+ G VT C V G P+P + W G G D +L
Sbjct: 1555 Y----KKKVFAKEGEEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHF 1610
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTC-TATG 318
D+V + EG Y C A++ + L+V P + N + V G +C T
Sbjct: 1611 DSVSVKQEGNYHCVAQSKGNILDIDVELSVLAVPIVGEDDN-LEVFLGKDISLSCDLQTE 1669
Query: 319 RPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
+ T F WS+ G+ + D+ + L I D K ++ +C N
Sbjct: 1670 SDDKTTFVWSINGSES--------DRPDNVQIPSDGHRLYITDA-KPENNGKYMCRVTNS 1720
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGE 436
AG + + T+T D PP + +NQ L + + C P+P + W +G
Sbjct: 1721 AG----KAERTLTLDVLEPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDGN 1776
Query: 437 ALIQNHRRNVTNDGTLVLKDLDK--SDSGTYTCVASSRHG 474
+ ++ D +L L ++K S +C A ++ G
Sbjct: 1777 DV----DKSWLFDESLSLLRIEKLTGKSAQISCTAENKAG 1812
Score = 104 bits (249), Expect = 4e-22
Identities = 98/387 (25%), Positives = 144/387 (37%), Gaps = 20/387 (5%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I P +T + +L C G P P I W G + + + A G +
Sbjct: 4139 ITSTPGVLTPSSGSKFSLPCAVRGYPDPIISWTLNGNDIKDGENGHTIGADGTLHIEKAE 4198
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R H +Y C A N G A + + V + ++G V++C
Sbjct: 4199 ER-HL---IYECTAKNDAG-ADTLEFPVQTIVAPKISTSGNRYINGSEGTETVIKCEIES 4253
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
S E + W KNG LL ++ + D + I R +D G Y C A N AG
Sbjct: 4254 ESSEFS--WSKNGVPLL-PSNNLIFSEDYKLIKILSTRLSDQGEYSCTAANKAGNATQK- 4309
Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG-GNMPLGRVKVL 252
L + + P ++ P V G VT C G P P + W + N +
Sbjct: 4310 TNLNVGVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATT 4369
Query: 253 DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARF 312
S+ ++ + G Y+C+AEN V + L V PP + +V+
Sbjct: 4370 KKKSVIFSSISPSQAGVYTCKAENWVASTEEDIDLIVMIPPEVVPERMNVSTNPRQTVFL 4429
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
+C ATG PEP + W + N I + +KY T L I + +D C
Sbjct: 4430 SCNATGIPEPVISWMRDSNIAI----QNNEKYQILG-----TTLAIRNVLPDDD-GFYHC 4479
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPI 399
A + AG KL V DRP PI
Sbjct: 4480 IAKSDAGQKIATRKLIVNKPSDRPAPI 4506
Score = 98.3 bits (234), Expect = 3e-20
Identities = 109/363 (30%), Positives = 152/363 (41%), Gaps = 31/363 (8%)
Query: 6 VTSGEAPYII-EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGV-LVVSDTHRSILPA 63
+T E P II E P V V + + CRA G P W K G+ L + + S+
Sbjct: 1264 LTVHEKPKIISEVPGVVDVVKGFTIEIPCRATGVPEVIRTWNKNGIDLKMDEKKFSVDNL 1323
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL--EPESKQSAQ 121
G L A +D G Y C TN GT++ T HV V L + +
Sbjct: 1324 GTLRIYEAD----KNDIGNYNCVVTNEAGTSQ---MTTHVDVQEPPIILPSTQTNNTAVV 1376
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQC 180
GD V L+C SP +V W + G + D++ ++V+ G LVIQ A DA Y C
Sbjct: 1377 GDRVELKCY-VEASPPASVTWFRRG--IAIGTDTKGYVVESDGTLVIQSASVEDATIYTC 1433
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDVVAQ----TGSSVTFQCRVGGDPLPDVLWR 236
A N AG E A L++ + DVV Q + C V +PLP + W
Sbjct: 1434 KASNPAGKAE---ANLQVTVIASPDIKDPDVVTQESIKESHPFSLYCPVFSNPLPQISWY 1490
Query: 237 RSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI 295
+ K DD L + + D G Y C A N+ G S S + V P ++
Sbjct: 1491 LNDKPLIDDKTSWKTSDDKRKLHVFKAKITDSGVYKCVARNAAGEGSKSFQVEVIVPLNL 1550
Query: 296 NLS--PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH-ATAVFDG 352
+ S V + G C +G P P + W V+G T++ PG KY AT DG
Sbjct: 1551 DESKYKKKVFAKEGEEVTLGCPVSGFPVPQINWVVDG--TVVEPG---KKYKGATLSNDG 1605
Query: 353 VTV 355
+T+
Sbjct: 1606 LTL 1608
Score = 97.5 bits (232), Expect = 5e-20
Identities = 87/342 (25%), Positives = 139/342 (40%), Gaps = 23/342 (6%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--IARNAAGTRESAIATLK 197
+YW K G+ ++ G H D I + DAG Y+C I+ N + ++ + T +
Sbjct: 460 IYWVKTGEDII-GGPLFYHNTDTSVWTIPELSLKDAGEYECRVISNNGNYSVKTRVETRE 518
Query: 198 IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR-SAGGGNMPLGRVKVLDDGS 256
P I G +V G + C ++ W R A N P + +G+
Sbjct: 519 ---SPPEIFGVRNVSVPLGEAAFLHCSTRSAGEVEIRWTRYGATVFNGP-NTERNPTNGT 574
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
L++ +V AD G Y C A N+ G + L + +PPS+ ++P V +C A
Sbjct: 575 LKIHHVTRADAGVYECMARNAGGMSTRKMRLDIMEPPSVKVTPQDVYFNMREGVNLSCEA 634
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G P+P + W +G ++ KY V L I D +D T C A++
Sbjct: 635 MGDPKPEVHWYFKGRHL-----LNDYKYQ---VGQDSKFLYIRDATHHD-EGTYECRAMS 685
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAI-CTPEPIIAWYFEG 435
AG + L + + PP + + + F C I P P I W+ G
Sbjct: 686 QAGQARDTTDLMLAT-----PPKVEIIQNKMMVGRGDRVSFECKTIRGKPHPKIRWFKNG 740
Query: 436 EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYV 477
+ LI+ N+G L + D+G Y+CV + GK V
Sbjct: 741 KDLIKPDDYIKINEGQLHIMGAKDEDAGAYSCVGENMAGKDV 782
Score = 93.5 bits (222), Expect = 8e-19
Identities = 106/471 (22%), Positives = 181/471 (38%), Gaps = 34/471 (7%)
Query: 10 EAPYIIEQPLDVT--VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
E P +E + + + P L C+ G+P P + W G +D +S L L
Sbjct: 1734 EPPVFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKIDG----NDVDKSWLFDESLS 1789
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ-SAQGDTVV 126
LR ++ + C A N GTA SR+ + + F+ E + + + +T+
Sbjct: 1790 LLRIE--KLTGKSAQISCTAENKAGTA-SRDFFIQ-NIAAPTFKNEGDQETIFRESETIT 1845
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L+C P + + W K G L + D+ + +D L I +A + Y C+A N A
Sbjct: 1846 LDC--PVSLGDFQITWMKQGLPLT-ENDA-IFTLDNTRLTILNANRDHEDIYTCVANNTA 1901
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
G + S + + + P + + G + C G+P P W G++P
Sbjct: 1902 G-QVSKDFDVVVQVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKW--DFNQGDLPK 1958
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNV 304
V V ++ ++ ++NV G Y C A N VG + + V P L+ + + V
Sbjct: 1959 EAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKTINVHVRTKPRFESGLTESELTV 2018
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
C + W+V G P ++ + G L I K
Sbjct: 2019 NLTRSITLECDVDDAIGVGISWTVNGK-----PFLA--ETDGVQTLAGGRFLHIVSA-KT 2070
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT 424
D + C+ N AG + L V + PP I N T+ + V PC
Sbjct: 2071 DDHGSYACTVTNEAGVATKTFNLFV-----QVPPTIVNEGGEYTVIENNSLVLPCEVTGK 2125
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRHG 474
P P++ W +G + V ++G + + + G+Y C+A + G
Sbjct: 2126 PNPVVTWTKDGRPVGDLKSVQVLSEGQQFKIVHAEIAHKGSYICMAKNDVG 2176
Score = 92.7 bits (220), Expect = 1e-18
Identities = 114/453 (25%), Positives = 176/453 (38%), Gaps = 45/453 (9%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
S S W K GV ++ + L + +T SD G Y C A N G A ++
Sbjct: 4253 SESSEFSWSKNGVPLLPSNNLIFSEDYKLIKILSTR---LSDQGEYSCTAANKAGNA-TQ 4308
Query: 98 NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
L+V V + P ++ +GD V L C G P+P + W K+ + L G
Sbjct: 4309 KTNLNVGVAPKIME-RPRTQVVHKGDQVTLWC-EASGVPQPAITWYKDNELLTNTGVDET 4366
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS 217
+++ + AG Y C A N + E I L + I P ++ +V
Sbjct: 4367 ATTKKKSVIFSSISPSQAGVYTCKAENWVASTEEDI-DLIVMIPPEVVPERMNVSTNPRQ 4425
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
+V C G P P + W R + + ++L +L + NV+ D+G Y C A++
Sbjct: 4426 TVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGT-TLAIRNVLPDDDGFYHCIAKSD 4484
Query: 278 VGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFP 337
G A+ L V P P + VE C G+P+ T + +I
Sbjct: 4485 AGQKIATRKLIVNKPSD---RPAPIWVE--------CDEKGKPKKTEY--------MIDR 4525
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
G + D D +L D + + +I Y R TV P
Sbjct: 4526 GDTPD--------DNPQLLPWKDVEDSSLNGSIA-----YRCMPGPRSSRTVLLH--AAP 4570
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
I P N T I ++ C+A P P I W +G+ LI++ + + V +
Sbjct: 4571 QFIVK-PKNTTAAIGAIVELRCSAAGPPHPTITWAKDGK-LIEDSKFEIAYSHLKVTLN- 4627
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
SDSG YTC+A + G S + VD+ I P
Sbjct: 4628 STSDSGEYTCMAQNSVGSSTVSAFINVDNNILP 4660
Score = 89.8 bits (213), Expect = 1e-17
Identities = 124/473 (26%), Positives = 194/473 (41%), Gaps = 62/473 (13%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGL 66
G AP I+E+P V + TL C A G P PAI WYK L+ + + +
Sbjct: 4315 GVAPKIMERPRTQVVHKGDQVTLWCEASGVPQPAITWYKDNELLTNTGVDETATTKKKSV 4374
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVV 126
F + S AGVY C+A N + + + L + ++ E E + + TV
Sbjct: 4375 IFSSIS----PSQAGVYTCKAEN-WVASTEEDIDL-IVMIPPEVVPERMNVSTNPRQTVF 4428
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
L C G PEP + W ++ + + + + + G L I++ D G Y CIA++ A
Sbjct: 4429 LSC-NATGIPEPVISWMRDSNIAIQNNEK--YQILGTTLAIRNVLPDDDGFYHCIAKSDA 4485
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGNM 244
G + IAT K+ ++ P D A + +C G P ++ R N
Sbjct: 4486 GQK---IATRKL-----IVNKPSDRPA----PIWVECDEKGKPKKTEYMIDRGDTPDDNP 4533
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV 304
L K ++D SL N +A Y C + +S + ++ P + P +
Sbjct: 4534 QLLPWKDVEDSSL---NGSIA----YRC-----MPGPRSSRTVLLHAAPQFIVKPKNTTA 4581
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
G + C+A G P PT+ W+ +G +I Y V T+N T +
Sbjct: 4582 AIGAIVELRCSAAGPPHPTITWAKDGK--LIEDSKFEIAYSHLKV-------TLNST--S 4630
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAIC 423
DS C A N GSS V + V ++ P P SNQ K++AV C
Sbjct: 4631 DS-GEYTCMAQNSVGSSTVSAFINV-DNNILPTP---KPSSNQ----KNVAVITCYERNQ 4681
Query: 424 TPEPIIAWYFEGEALIQNHRR-NVTNDGTLVLKD---LDKSDSGTYTCVASSR 472
+ W + G + +N + N+G+LV+ D L + D YTC +R
Sbjct: 4682 AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRNR 4734
Score = 88.2 bits (209), Expect = 3e-17
Identities = 88/309 (28%), Positives = 130/309 (42%), Gaps = 26/309 (8%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP I +P + T A L C A G P P I W K G L + D+ I + L
Sbjct: 4569 APQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITWAKDGKL-IEDSKFEIAYSHLKVTLN 4627
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
+T SD+G Y C A NS G ++T+ + + L S Q + V+ C
Sbjct: 4628 ST-----SDSGEYTCMAQNSVG-----SSTVSAFINVDNNILPTPKPSSNQKNVAVITCY 4677
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA---RQTDAGRYQCIARNAAG 187
+ + W+ NG + + +H ++ G+LVI D ++ D Y C RN
Sbjct: 4678 ERNQAYSRGLTWEYNGVPMP-KNLAGIHFMNNGSLVILDTSSLKEGDLELYTCKVRN--- 4733
Query: 188 TRESAIATLKIHIK--PYLITGPEDVVAQTGSSVTFQCRVGGDPL-PDVLWRRSAGGGNM 244
R +I L + P + T + V G SV C V DPL V+W ++ +
Sbjct: 4734 RRRHSIPHLTSAFEGVPEVKT-IDKVEVNNGDSVVLDCEVTSDPLTTHVVWTKN-DQKML 4791
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP---PSINLSPNS 301
+ VL + SL L NV DEG Y C A NS+G L VY+ P +
Sbjct: 4792 DDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGKAFDDTQLNVYEGDFLPLTGFEGSG 4851
Query: 302 VNVESGNVA 310
+N++ + A
Sbjct: 4852 INIDDSSNA 4860
Score = 82.2 bits (194), Expect = 2e-15
Identities = 109/467 (23%), Positives = 178/467 (38%), Gaps = 52/467 (11%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P ++ + ++V+ Q L+C A G P P I W + + + + + + L A
Sbjct: 4410 PEVVPERMNVSTNPRQTVFLSCNATGIPEPVISWMRDSNIAIQNNEKYQILGTTL----A 4465
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ D G Y C A + G + AT + V + R P + +EC
Sbjct: 4466 IRNVLPDDDGFYHCIAKSDAG---QKIATRKLIVNKPSDRPAP----------IWVEC-D 4511
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRES 191
+G P+ Y G T D L+ + ++D+ + Y+C+ G R S
Sbjct: 4512 EKGKPKKTEYMIDRGDT----PDDNPQLLPWKD--VEDSSLNGSIAYRCMP----GPRSS 4561
Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
T+ +H P I P++ A G+ V +C G P P + W A G +
Sbjct: 4562 R--TVLLHAAPQFIVKPKNTTAAIGAIVELRCSAAGPPHPTITW---AKDGKLIEDSKFE 4616
Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
+ L++ +D GEY+C A+NSVG+ + S ++ V + P+S NVA
Sbjct: 4617 IAYSHLKVTLNSTSDSGEYTCMAQNSVGSSTVSAFINVDNNILPTPKPSS---NQKNVAV 4673
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD--KNDSRNT 369
TC + + T + G+ K A F L I DT K
Sbjct: 4674 ITCYERNQ-------AYSRGLTWEYNGVPMPKNLAGIHFMNNGSLVILDTSSLKEGDLEL 4726
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP-EPI 428
C N S +TS + P + T + V C P
Sbjct: 4727 YTCKVRNRRRHSIPH----LTSAFEGVPEVKT--IDKVEVNNGDSVVLDCEVTSDPLTTH 4780
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
+ W + ++ + V + +LVL +++K D G Y CVAS+ GK
Sbjct: 4781 VVWTKNDQKMLDDDAIYVLPNNSLVLLNVEKYDEGVYKCVASNSIGK 4827
Score = 77.8 bits (183), Expect = 4e-14
Identities = 79/334 (23%), Positives = 134/334 (40%), Gaps = 20/334 (5%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
D ++ + AP + T+ R + TL+C I W K G+ + + L
Sbjct: 1817 DFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSLGDFQ-ITWMKQGLPLTENDAIFTL 1875
Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
L L A R H D +Y C A N+ G S++ + V VL + + + + +
Sbjct: 1876 DNTRLTILNAN--RDHED--IYTCVANNTAGQV-SKDFDVVVQVL-PKIKNAVVTLEINE 1929
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G+ ++L C G+P P W N L + + + + +V+ + + G Y+C
Sbjct: 1930 GEEIILTC-DAEGNPTPTAKWDFNQGDLPKEA---VFVNNNHTVVVNNVTKYHTGVYKCY 1985
Query: 182 ARNAAGTRESAIATLKIHI--KPYLITG--PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
A N G A+ T+ +H+ KP +G ++ S+T +C V + W
Sbjct: 1986 ATNKVG---QAVKTINVHVRTKPRFESGLTESELTVNLTRSITLECDVDDAIGVGISWTV 2042
Query: 238 SAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ V+ L G L + + D G Y+C N G + + L V PP+I
Sbjct: 2043 NGKPFLAETDGVQTLAGGRFLHIVSAKTDDHGSYACTVTNEAGVATKTFNLFVQVPPTIV 2102
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
V N C TG+P P + W+ +G
Sbjct: 2103 NEGGEYTVIENNSLVLPCEVTGKPNPVVTWTKDG 2136
Score = 76.6 bits (180), Expect = 1e-13
Identities = 120/515 (23%), Positives = 196/515 (38%), Gaps = 46/515 (8%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
+ TL C G P P I W G +V ++ + L V + G Y C
Sbjct: 1565 EEVTLGCPVSGFPVPQINWVVDGTVVEPGKKYKGATLSNDGLTLHFDSVSVKQE-GNYHC 1623
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKK 144
A + + + ++VL E ++ + G + L C L + W
Sbjct: 1624 VAQSK---GNILDIDVELSVLAVPIVGEDDNLEVFLGKDISLSCDLQTESDDKTTFVWSI 1680
Query: 145 NGQTLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
NG D + + DG L I DA+ + G+Y C N+AG E + TL + ++P
Sbjct: 1681 NGSE--SDRPDNVQIPSDGHRLYITDAKPENNGKYMCRVTNSAGKAERTL-TLDV-LEPP 1736
Query: 204 LITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-SLRL 259
+ P Q + + QC+V G+P P V+W+ GN + + + D+ SL
Sbjct: 1737 VFVEPVFEANQKLIGNNPIILQCQVTGNPKPTVIWKID---GN-DVDKSWLFDESLSLLR 1792
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNV--ESGNVARFTCTAT 317
+ + SC AEN G S ++ P+ + + ES + +
Sbjct: 1793 IEKLTGKSAQISCTAENKAGTASRDFFIQNIAAPTFKNEGDQETIFRESETITLDCPVSL 1852
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
G + T W +G P D A D T LTI + ++ D + C A N
Sbjct: 1853 GDFQIT--WMKQG-----LPLTEND---AIFTLDN-TRLTILNANR-DHEDIYTCVANNT 1900
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
AG + V + P I N + + C A P P W F +
Sbjct: 1901 AGQVSKDFDVVV-----QVLPKIKNAVVTLEINEGEEIILTCDAEGNPTPTAKWDF-NQG 1954
Query: 438 LIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRA 497
+ V N+ T+V+ ++ K +G Y C A+++ G+ V + ++ + F
Sbjct: 1955 DLPKEAVFVNNNHTVVVNNVTKYHTGVYKCYATNKVGQAVKT----INVHVRTKPRFESG 2010
Query: 498 ADVSSLPGPPTKPIT--HNVTDT-SVTLSWSQNNK 529
S L T+ IT +V D V +SW+ N K
Sbjct: 2011 LTESELTVNLTRSITLECDVDDAIGVGISWTVNGK 2045
>AF003131-5|AAV34799.1| 5992|Caenorhabditis elegans Uncoordinated
protein 89, isoform e protein.
Length = 5992
Score = 146 bits (354), Expect = 8e-35
Identities = 178/689 (25%), Positives = 281/689 (40%), Gaps = 110/689 (15%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAG 64
VT+ + P + DV QP L C+ SP P + WYK G +V SD + L
Sbjct: 5055 VTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPD 5114
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLREEFR--- 111
G+ L V+ D G+Y ATN GTA+ R++ + R+ F
Sbjct: 5115 GVATLLIP-SCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANK 5173
Query: 112 ----LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-- 164
+EP E+ + + + L C G P+P + W K+G+ + G R+ L++ +
Sbjct: 5174 APKLMEPLENIRIPEKQSFRLRC-KFSGDPKPTIKWFKDGERVFPYG--RLQLIESPDGV 5230
Query: 165 --LVIQDARQTDAGRYQCIARNAAGTRESA--IATLKIHIKPYLI------------TGP 208
LV+ A + DAG Y+C+A N G+ ++ + ++ KP I T P
Sbjct: 5231 CELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTP 5290
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL--DNVI 263
+ A+ G SVTF+C G+P P + W + G ++K+ DG+ RL +V
Sbjct: 5291 LTIRRAKPGDSVTFECLPFGNPFPSIKWLKD-GLELFSDEKIKMEAAADGTQRLILSDVT 5349
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDP--------PSINLSPN-----------SVNV 304
EG + C A N G S L + P +N P ++++
Sbjct: 5350 FLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMSI 5409
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
GNV ATG P PT+ W +G + I+ G + T G+ L I + +
Sbjct: 5410 HEGNVVEMIVCATGIPTPTVKWYKDG-QEIVGDGPDGKRVIFTDE-RGIHHLVIVNASPD 5467
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLT------VTSDDDRP----PPIITNGPSNQTLPIKSM 414
D A N GS+ G L + D+R PP N+ +
Sbjct: 5468 D-EGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMP 5526
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVAS 470
+F C + P P + W+ G+ ++ R + + G L++ D D+G Y A
Sbjct: 5527 TIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATAK 5586
Query: 471 SRHGKYVWSGALLVDSPINPNIHF---------------FRAADVSSLPGPPTK-PITHN 514
+ HG S L V P +I F F+ + +SLP PP + P
Sbjct: 5587 NSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKKLNTASLPTPPDRGPFIKE 5646
Query: 515 VTDTSVTLSWSQNNKIGSS-SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
VT +TLSW + + Y +E+ RE + W ++ + +
Sbjct: 5647 VTGHYLTLSWIPTKRAPPRYPQVTYVIEI--REL--------PEKQWSLLEYNIPEPVCK 5696
Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVS 602
V++L G +Y F VR EN +G+S PSP S
Sbjct: 5697 VRNLELGKSYQFRVRAENIYGISDPSPAS 5725
Score = 140 bits (339), Expect = 5e-33
Identities = 139/499 (27%), Positives = 208/499 (41%), Gaps = 62/499 (12%)
Query: 28 PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-PAGGLFFLRATHGRVHSDAGVYWCE 86
P + C +P+ + W+K G + H I G ++ SD GVY C
Sbjct: 4653 PMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFE-ESDIGVYMCV 4711
Query: 87 ATNSYGTARSRNATLHVAVL-------REEF--RLEP--ESKQSAQGDTVVLECLPPRGS 135
A N G A ++ AT V +L R E+ ++ P E K G + L C
Sbjct: 4712 AVNELGQAETQ-ATYQVEILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSC-KVDAI 4769
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGT-RESA 192
P +V W K+G L D + + + G L I D+ + D G Y+C+A NA GT S
Sbjct: 4770 PRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSC 4829
Query: 193 IATLKI---HIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGN 243
+K+ +K P+ G D+ A G S T +C V GDP P++ W R+ N
Sbjct: 4830 SVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRN 4889
Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY----------- 290
P ++ DG SL ++ ++DEG Y CEAEN+ G V
Sbjct: 4890 GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKM 4949
Query: 291 ---DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
PP L + ++V GNV C TG P P++ WS +G I SR ++ +
Sbjct: 4950 DEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLI---EDSRFEW-SN 5005
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSN 406
GV L I + +D T C A N GS+ K V DD ++T + P
Sbjct: 5006 EASKGVYQLRIKNATVHD-EGTYRCVATNENGSATT--KSFVRMDDGLGSGVVTASQPPR 5062
Query: 407 QTLPIKSMAV-------FPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDG--TLVLK 455
TL + + C +P P + WY +G + + R + + DG TL++
Sbjct: 5063 FTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIP 5122
Query: 456 DLDKSDSGTYTCVASSRHG 474
D G Y +A++ G
Sbjct: 5123 SCVYDDDGIYRVIATNPSG 5141
Score = 139 bits (336), Expect = 1e-32
Identities = 142/521 (27%), Positives = 221/521 (42%), Gaps = 71/521 (13%)
Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I PL D TV QP L+C+ P ++ WYK G+ + +D+ SI A +
Sbjct: 4745 INPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIN 4804
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---------QSAQGDT 124
D G Y C ATN++GT + + +++V V ++E + E E + +GD+
Sbjct: 4805 DSTEEDIGAYRCVATNAHGTINT-SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDS 4863
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGG-NLVIQDARQTDAGRYQCI 181
L+C G P P + W +NGQ LL +G + DG +L + ++ +D G Y+C
Sbjct: 4864 FTLKC-AVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 4921
Query: 182 ARNAAG-TRESAIATLKIHI----KPYLITGP--------EDVVAQTGSSVTFQCRVGGD 228
A NA G + A A +++ + KP + G D+ G+ + +C+V G
Sbjct: 4922 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGL 4981
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVS- 282
P P V W + GG + R + ++ S LR+ N + DEG Y C A N G+ +
Sbjct: 4982 PNPSVKWSKD-GGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATT 5040
Query: 283 ----------ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
SG +T PP L V G + C P P M W +G
Sbjct: 5041 KSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG-- 5098
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--- 389
I+ P D+ + DGV L I +D V A N +G++ +G TV
Sbjct: 5099 AIVTPS---DRIQISLSPDGVATLLIPSCVYDDDGIYRVI-ATNPSGTAQDKGTATVKKL 5154
Query: 390 --------TSD----DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
++D D P + N +P K C P+P I W+ +GE
Sbjct: 5155 PRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGER 5214
Query: 438 LIQNHRRNV--TNDGT--LVLKDLDKSDSGTYTCVASSRHG 474
+ R + + DG LV+ + D+G Y CVA + +G
Sbjct: 5215 VFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYG 5255
Score = 136 bits (328), Expect = 1e-31
Identities = 127/499 (25%), Positives = 210/499 (42%), Gaps = 32/499 (6%)
Query: 7 TSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PA 63
T EAP + EQ L T V + + + GGS +P + W+K V D + + P
Sbjct: 2544 TKVEAP-VFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDDKPVSEDGNHEMKKNPE 2601
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQG 122
G+F L +DAG Y +A+N GTA S A + ++ + F E + +
Sbjct: 2602 TGVFTLVVKQAAT-TDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKIN 2660
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQ 179
+T L + +G P+P+V W K+GQ + D + V+G ++ I+DAR D+G+Y
Sbjct: 2661 ETATLS-VTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYA 2719
Query: 180 CIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
C A N AG E+ A +K + P + + + S T +V G P P V W +
Sbjct: 2720 CRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFK 2779
Query: 238 SAGGGNMP----LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYD- 291
++ + + + SL +++ D G YSC A N G A++ + + + D
Sbjct: 2780 DDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS 2839
Query: 292 -PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
PP + V T G P P + W + ++ I + A
Sbjct: 2840 IPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEW-FKDDKPI---NIDNSHIFAKDEG 2895
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G LTI + + C A N AG + + V + + P + G +
Sbjct: 2896 SGHHTLTIKQA-RGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP--LFVQGLKPYEVE 2952
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTY 465
A PEP + W+ +G + +++ + G TLV+KD + +D G Y
Sbjct: 2953 QGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKY 3012
Query: 466 TCVASSRHGKYVWSGALLV 484
TC A+++ GK G L +
Sbjct: 3013 TCQATNKAGKDETVGELKI 3031
Score = 135 bits (327), Expect = 2e-31
Identities = 129/483 (26%), Positives = 199/483 (41%), Gaps = 34/483 (7%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + + G P P I WYK V + D + FF +D G Y C AT
Sbjct: 565 AKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMAT 624
Query: 89 NSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
N YG A S +A V + +E F + K+ +GD + EC G PEP + W
Sbjct: 625 NEYGQA-STSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFEC-EVEGWPEPELVWL 682
Query: 144 KNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL----- 196
+ Q L D R+ DG L I+DA+ D G Y +N G+ ES
Sbjct: 683 VDDQPLRPSHDFRLQ-YDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADP 741
Query: 197 -KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDD 254
K H+ P E V G V F+ + GDP P+++W + G +VK + +D
Sbjct: 742 DKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFIN-GKPLSESEKVKFISED 800
Query: 255 G--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNV 309
G L + +V +G +C+ N +G+ S G L V PP+ N V+ +
Sbjct: 801 GICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKST 860
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
F +G PEPT+ +++ G + ++ DG ++I +T +
Sbjct: 861 VVFEVDVSGWPEPTLTFTLCGKEL-----KNGEEGVEIVGHDGFYRISIPNTSMDKHDGE 915
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDD--RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
IV A N G++ R +LTV +++ R P +QT+ AVF T P P
Sbjct: 916 IVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNP 975
Query: 428 IIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
+ W+ G + Q + N + D +GT C A + G++ L+V
Sbjct: 976 EVTWFINGHKMDQGSPGVKIEAHNHDHKLTID-SAQYAGTVLCRAENAVGRFETKARLVV 1034
Query: 485 DSP 487
+P
Sbjct: 1035 LAP 1037
Score = 126 bits (303), Expect = 1e-28
Identities = 139/544 (25%), Positives = 222/544 (40%), Gaps = 78/544 (14%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GE P+ + +D+ R TL C G P P I+WY+ G L+ + I +
Sbjct: 4844 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC 4903
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREE-----------FRLEPE 115
+ SD G+Y CEA N++G A+++ AT HV A+ + E F LE
Sbjct: 4904 SLTVNESTMSDEGIYRCEAENAHGKAKTQ-ATAHVQMALGKTEKPKMDEGKPPKFILELS 4962
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-----LVIQDA 170
+ G+ + LEC G P P+V W K+G L+ DSR + + L I++A
Sbjct: 4963 DMSVSLGNVIDLEC-KVTGLPNPSVKWSKDGGPLI--EDSRFEWSNEASKGVYQLRIKNA 5019
Query: 171 RQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPE---------DVVAQTGSSVT 220
D G Y+C+A N G+ + + + + ++T + DV G +
Sbjct: 5020 TVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLK 5079
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDG--SLRLDNVILADEGEYSCEAEN 276
+C+V PLP+++W + G P R+++ DG +L + + + D+G Y A N
Sbjct: 5080 LECKVDASPLPEMVWYKD-GAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATN 5138
Query: 277 SVGAVSASGYLTVYDPP--------------SINLSP------NSVNVESGNVARFTCTA 316
G G TV P N +P ++ + R C
Sbjct: 5139 PSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKF 5198
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
+G P+PT+ W +G R +FP + DGV L ++ + D+ C A N
Sbjct: 5199 SGDPKPTIKWFKDGER--VFP---YGRLQLIESPDGVCELVVDSATRQDA-GGYRCVAEN 5252
Query: 377 YAGSSFVRGKLTVTSDDDRPPPI---ITNGPS-NQTLPIK-------SMAVFPCTAICTP 425
GS+ + V D +P I I G + T P+ F C P
Sbjct: 5253 TYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNP 5312
Query: 426 EPIIAWYFEGEALIQNH--RRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P I W +G L + + DGT L+L D+ G + CVA++ HG
Sbjct: 5313 FPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 5372
Query: 482 LLVD 485
L+++
Sbjct: 5373 LVIE 5376
Score = 124 bits (298), Expect = 5e-28
Identities = 126/498 (25%), Positives = 203/498 (40%), Gaps = 46/498 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLF 67
E P + + + V ++ ATL+ G P P++ W K G V +D+ I + G +
Sbjct: 2644 EKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSY 2703
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEF--RLEPESKQSAQGDT 124
+ R+ D+G Y C ATN G A++ N + ++ EF +L P + + T
Sbjct: 2704 SITIKDARLE-DSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTT 2762
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCI 181
+ ++ + G+PEP+V W K+ + D + V +L I DARQ D G Y C
Sbjct: 2763 LSVKVV---GTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCR 2819
Query: 182 ARNAAG--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
ARN AG + ++ I P + + ++ + V G P+P+V W +
Sbjct: 2820 ARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDD 2879
Query: 240 GGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
N+ + D+GS L + D G Y+C+A N G + + V +
Sbjct: 2880 KPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEA 2939
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV--F 350
P VE G A G+PEP + W +G I D H
Sbjct: 2940 PLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAI------DNQHVIEKKGE 2993
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--------TSDDDRPPPIITN 402
+G L I DT+ D C A N AG G+L + T+++ +P +
Sbjct: 2994 NGSHTLVIKDTNNADF-GKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKP---LFI 3049
Query: 403 GPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR-NVTNDGT--LVLKDL 457
P +T ++ V C P I ++ + + I H + V DG L +++
Sbjct: 3050 EPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNA 3109
Query: 458 DKSDSGTYTCVASSRHGK 475
K D G Y C A + GK
Sbjct: 3110 KKEDVGAYRCEAVNVAGK 3127
Score = 114 bits (275), Expect = 3e-25
Identities = 138/493 (27%), Positives = 199/493 (40%), Gaps = 41/493 (8%)
Query: 11 APYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
AP +PL D TV G P P + + G L + I+ G +
Sbjct: 842 APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYR 901
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP------ESKQSAQG 122
+ + + G +A N +GTA SR A L V EE R P E + G
Sbjct: 902 ISIPNTSMDKHDGEIVAKAQNEHGTAESR-ARLTVEQEEEESRSAPTFLKDIEDQTVKTG 960
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRY 178
+ V E RG+P P V W NG + D S ++ N L I A+ AG
Sbjct: 961 EFAVFETTV-RGNPNPEVTWFINGHKM--DQGSPGVKIEAHNHDHKLTIDSAQY--AGTV 1015
Query: 179 QCIARNAAGTRES-----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
C A NA G E+ +A K P + D ++V F+ RV G+P P V
Sbjct: 1016 LCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTV 1075
Query: 234 LWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVY 290
W G RV++ + DGS+++ N+ + D GE A NS G+ LTV
Sbjct: 1076 TWYLK-GEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134
Query: 291 DPP---SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P +L P S+ VE G+ A F+ A G P PT WSV G + +R +
Sbjct: 1135 KKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDES 1194
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAV--NYAGSSFVRGKLTVTSDDDRPP-PIITNGP 404
V DG ++LTI+ N + S V N G+ +LT+ + +PP P +T
Sbjct: 1195 TV-DGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTI--EPKKPPAPKLTRDL 1251
Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK---DLDKSD 461
QT+ +A F E W+ +G+ + V+ D + D
Sbjct: 1252 KLQTVNKTDLAHFEVVVEHATE--CKWFLDGKEITTAQGVTVSKDDQFEFRCSIDTTMFG 1309
Query: 462 SGTYTCVASSRHG 474
SGT + VAS+ G
Sbjct: 1310 SGTVSVVASNAAG 1322
Score = 112 bits (270), Expect = 1e-24
Identities = 127/493 (25%), Positives = 204/493 (41%), Gaps = 39/493 (7%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGG 65
T AP +E TV Q A L C+ G P P I+W K G V +S R+ G
Sbjct: 3172 TGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDG 3231
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---- 121
L +DAG Y CEA N YG+A + + L +++ E+ Q
Sbjct: 3232 TLTL-TFDNVTQADAGEYRCEAENEYGSAWTEGPI--IVTLEGAPKIDGEAPDFLQPVKP 3288
Query: 122 -----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTD 174
G+T VLE G P+P+V W KNG+ L ++ +D G L + +A+ D
Sbjct: 3289 AVVTVGETAVLEG-KISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDD 3347
Query: 175 AGRYQCIARNAAGTRESAIA-TLK--IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
Y+C A N G S + T+K + P + + + F+C+V G P
Sbjct: 3348 MDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECKVSGTK-P 3406
Query: 232 DVLWRRSAGGGNMPLGRV--KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYL 287
DV W + G RV + DDG+ RL ++ D+G Y E N G ++ L
Sbjct: 3407 DVKWFKD-GTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPL 3465
Query: 288 TVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
TV ++ + VNV G + G+P+ T+ W +G T+ S
Sbjct: 3466 TVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPK-TVKW-YKGTETV----TSSQTTK 3519
Query: 346 ATAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDR-PPPIITNG 403
V + L I + +D+ +V S +++ S +TVT ++ P G
Sbjct: 3520 IVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVES--SATVTVTKAAEKISLPSFKKG 3577
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDS 462
++Q++P + V P+ + WY G+ + ++ N L + D + D
Sbjct: 3578 LADQSVPKGTPLVLEVEIEGKPKD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDV 3636
Query: 463 GTYTCVASSRHGK 475
G Y+ A++ G+
Sbjct: 3637 GEYSVTAANEAGE 3649
Score = 107 bits (257), Expect = 5e-23
Identities = 120/492 (24%), Positives = 196/492 (39%), Gaps = 35/492 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P +++ P VT+ + A G P+P ++W +V + + ++ L+
Sbjct: 1435 PIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKI 1494
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLEC 129
++ ++ G A NS G S+ A L V V +F+ + K + +G+ +
Sbjct: 1495 SNAKI-EQTGTVKVTAQNSAG-QDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNL 1552
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNA 185
SP V W NGQ L + +VD G ++ I +A+ +G A+NA
Sbjct: 1553 ELDGPSPGTEVSWLLNGQPL--TKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNA 1610
Query: 186 AGTRE-SAIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
AG E SA T+ + KP + P++ SV F V G P+P+V W ++
Sbjct: 1611 AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLI 1670
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPSIN 296
+ + V S+R+ ++ G EAEN G V A+ L V + P
Sbjct: 1671 QSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFT 1730
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTV 355
+ + V+ G +FT G PEP++ W++ G P ++ DK DG
Sbjct: 1731 TNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDK-------DGEHT 1783
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I+ + + C A N GS +L V D P ++ + +
Sbjct: 1784 IEISAVTP-EQAGELSCEATNPVGSKKRDVQLAVKKVGD--APTFAKNLEDRLITEGELT 1840
Query: 416 VFPCTA-ICTPEPIIAWYFEG-EALIQNHRRNV-TNDGTLVLKDLDK--SDSGTYTCVAS 470
+ I P+P I W +G E H + V DG+L L L D G T A
Sbjct: 1841 LMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAE 1900
Query: 471 SRHGKYVWSGAL 482
S G S +L
Sbjct: 1901 SEFGVAECSASL 1912
Score = 106 bits (255), Expect = 8e-23
Identities = 116/490 (23%), Positives = 195/490 (39%), Gaps = 39/490 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP I D T + L C+ G P P + W + ++ ++ G+ +
Sbjct: 2352 KAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQES-ITVESVEGVERV 2410
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
T + S G Y C A N+ GT+++ A L V F E ++K+ + G+ +VL C
Sbjct: 2411 TITSSEL-SHQGKYTCIAENTEGTSKT-EAFLTVQGEAPVFTKELQNKELSIGEKLVLSC 2468
Query: 130 LPPRGSPEPNVYWKKNGQTLLFD----GDSRMHLV-DGGN----LVIQDARQTDAGRYQC 180
+GSP+P+V + +T + SR+ + D N +VI + D Y+
Sbjct: 2469 -SVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKA 2527
Query: 181 IARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS- 238
IA N+ GT S + T K+ P G + + + + +VGG PDV W +
Sbjct: 2528 IATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDD 2585
Query: 239 ---AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
+ GN + + +L + D G+Y+ +A N G +S V +
Sbjct: 2586 KPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEK 2645
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD- 351
P+ + V+ A + T G P+P++ W +G + D H A +
Sbjct: 2646 PTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQ------PVQTDSSHVIAKVEG 2699
Query: 352 -GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G +TI D DS C A N AG + V + PP S +
Sbjct: 2700 SGSYSITIKDARLEDS-GKYACRATNPAGEAKTEANFAVVK--NLVPPEFVEKLSPLEVK 2756
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEAL-IQN----HRRNVTNDGTLVLKDLDKSDSGTY 465
K + TPEP + W+ + + I N ++ +L + D + D G Y
Sbjct: 2757 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIY 2816
Query: 466 TCVASSRHGK 475
+C A + G+
Sbjct: 2817 SCRARNEAGE 2826
Score = 104 bits (249), Expect = 4e-22
Identities = 126/505 (24%), Positives = 191/505 (37%), Gaps = 36/505 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GEAP ++ + ++ + L+C GSP P + +Y +T + +
Sbjct: 2444 GEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEH 2503
Query: 69 LRA-THGRV------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
+ TH R+ D Y ATNS GTA S T + E E K+++
Sbjct: 2504 DQTNTHWRMVISQITKEDIVSYKAIATNSIGTATS---TSKITTKVEAPVFEQGLKKTSV 2560
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGG--NLVIQDARQTDAGRY 178
+ ++ G P+V W K+ + + DG+ M + G LV++ A TDAG+Y
Sbjct: 2561 KEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKY 2620
Query: 179 QCIARNAAGTRES---AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
A N AGT ES A T + KP + + + T V G P P V W
Sbjct: 2621 TAKASNPAGTAESSAEAEVTQSLE-KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEW 2679
Query: 236 RRSAGGGNMPLGRV--KVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
+ V KV G S+ + + L D G+Y+C A N G V
Sbjct: 2680 LKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVK 2739
Query: 292 ---PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
PP + + V+ + G PEP++ W + I K A
Sbjct: 2740 NLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVG 2799
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
F LTIND + D C A N AG + + D PP T
Sbjct: 2800 SFS----LTINDARQGDV-GIYSCRARNEAGEALTTANFGIIRDS--IPPEFTQKLRPLE 2852
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG----TLVLKDLDKSDSG 463
+ + T I TP P + W+ + + + I N ++G TL +K D G
Sbjct: 2853 VREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVG 2912
Query: 464 TYTCVASSRHGKYVWSGALLVDSPI 488
YTC A++ G+ + + V I
Sbjct: 2913 VYTCKATNEAGEAKTTANMAVQEEI 2937
Score = 99.5 bits (237), Expect = 1e-20
Identities = 125/500 (25%), Positives = 188/500 (37%), Gaps = 54/500 (10%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA-GGLFFLRATHGRVHS 78
D V TL C G P P + W K GV++ D ++ A G LR + S
Sbjct: 4439 DTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAK-KS 4497
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPR 133
D G Y A N G+A S + + V E+ F + ++ + GD + R
Sbjct: 4498 DIGQYRVTAKNEAGSATS-DCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFN-VKVR 4555
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
G P+P + W NG + FD + + GN L I+D R+ D G +CIA+N GT E+
Sbjct: 4556 GLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDET 4615
Query: 192 AIATLK-----------IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
+ + P D G + +C V +P +V W +
Sbjct: 4616 VCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGK 4675
Query: 241 G-GNMPLGRVKVLDDGSLRLDNVIL--ADEGEYSCEAENSVG--AVSASGYLTVYD---- 291
+ ++ DG+ R+ + +D G Y C A N +G A+ + + +
Sbjct: 4676 KIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEE 4735
Query: 292 ------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
P IN V G R +C P ++ W +G P + +
Sbjct: 4736 EKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG-----LPLRADSRTS 4790
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG----SSFVRGKLTVTS-DDDRPPPII 400
DG L IND+ + D C A N G S V K+ + P
Sbjct: 4791 IQYEEDGTATLAINDSTEEDI-GAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFF 4849
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV---TNDG--TLVLK 455
T G + C P P I WY G+ L++N R V + DG +L +
Sbjct: 4850 TKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVN 4908
Query: 456 DLDKSDSGTYTCVASSRHGK 475
+ SD G Y C A + HGK
Sbjct: 4909 ESTMSDEGIYRCEAENAHGK 4928
Score = 97.5 bits (232), Expect = 5e-20
Identities = 118/443 (26%), Positives = 172/443 (38%), Gaps = 64/443 (14%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + +AP ++E ++ + Q L C+ G P P I+W+K G V ++ +
Sbjct: 5167 DVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIES 5226
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLRE----E 109
DAG Y C A N+YG+AR+ R + +RE
Sbjct: 5227 PDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPG 5286
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
F +++ GD+V ECL P G+P P++ W K+G L D +M G L++
Sbjct: 5287 FTTPLTIRRAKPGDSVTFECL-PFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLIL 5345
Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKI-------------------HIKPYLITGP 208
D G ++C+A N GT S A L I KP + G
Sbjct: 5346 SDVTFLSEGYFRCVATNEHGT-ASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGL 5404
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDD----GSLRLDNV 262
++ G+ V G P P V W + G+ P G+ + D L + N
Sbjct: 5405 YNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNA 5464
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---------NLSPNSV-NVESGNVAR- 311
DEGEYS EA N +G+ G L + P I P V +++ +V
Sbjct: 5465 SPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNH 5524
Query: 312 ----FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
F C G P P + W G + I PG R K + G L I DT D+
Sbjct: 5525 MPTIFDCLVVGHPAPEVEWFHNGKK--IVPG-GRIKIQSCG--GGSHALIILDTTLEDA- 5578
Query: 368 NTIVCSAVNYAGSSFVRGKLTVT 390
V +A N GS+ L VT
Sbjct: 5579 GEYVATAKNSHGSASSSAVLDVT 5601
Score = 96.3 bits (229), Expect = 1e-19
Identities = 125/542 (23%), Positives = 206/542 (38%), Gaps = 42/542 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLFFL 69
P ++ P + + + G P P + WY ++ + + G +
Sbjct: 1629 PEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSI 1688
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
R + + G EA N G ++ A L V E +F + +Q +G+ V
Sbjct: 1689 RIQKPLMEHN-GTIRVEAENVSGKVQA-TAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKF 1746
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAA 186
G PEP+V W NG+ + + + DG + + I AG C A N
Sbjct: 1747 TA-NVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPV 1805
Query: 187 GT--RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243
G+ R+ +A K+ P ED + G ++ P P + W + G
Sbjct: 1806 GSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKD-GVEI 1864
Query: 244 MPLGRVKVLD--DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPS 294
G K+++ DGSL+L L D+G + +AE+ G S L V P+
Sbjct: 1865 TSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPA 1924
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+N+ G+ TG P P + W + G + + + D + A +GV
Sbjct: 1925 FQSDIAPINLTEGDTLECKLLITGDPTPFVKWYI-GTQLVC---ATEDTEISNA--NGVY 1978
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKS 413
+ I+ D I C A N AG G L V + P P+ + T
Sbjct: 1979 TMKIHGVTA-DMTGKIKCVAYNKAGEVSTEGPLKVVA----PIPVEFETSLCDATCREGD 2033
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
+ PEP+++WY G+ L ++ + ++ T+ +KD+ SG C A
Sbjct: 2034 TLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAI 2093
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT---DTSVTLSWSQN 527
+ +GK LLV P ++V + G TK + H V D +L+W N
Sbjct: 2094 NEYGKATSEATLLVLPRGEPPDFLEWLSNVRARTG--TK-VVHKVVFTGDPKPSLTWYIN 2150
Query: 528 NK 529
NK
Sbjct: 2151 NK 2152
Score = 92.7 bits (220), Expect = 1e-18
Identities = 117/517 (22%), Positives = 201/517 (38%), Gaps = 69/517 (13%)
Query: 32 NCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRATHGRVHSDAGVYWCEATNS 90
N + G P P ++W+ G+ + D ++ A G + L R D G C A N
Sbjct: 4551 NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVR-EEDFGTLKCIAKNE 4609
Query: 91 YGTARS----RNATLHVAVLREEFRLEPE------SKQSAQGDTVVLECLPPRGSPEPNV 140
GT + + H R++ R P ++ GD + +EC +P V
Sbjct: 4610 NGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVD-ANPTAEV 4668
Query: 141 YWKKNGQTLLFDGDSRM-HLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
W K+G+ + + + + VDG + I ++D G Y C+A N G E+ AT ++
Sbjct: 4669 EWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQ-ATYQV 4727
Query: 199 HIKPYL-----------ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
I ++ I P ED G + C+V P V+W + +PL
Sbjct: 4728 EILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG----LPL 4783
Query: 247 GR-----VKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------- 292
++ +DG+ L +++ D G Y C A N+ G ++ S + V P
Sbjct: 4784 RADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE 4843
Query: 293 ---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P + + G+ C TG P P + W G + R +
Sbjct: 4844 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ---LLRNGPRTVIETSP- 4899
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---------GKLTVTSDDDRPPPII 400
DG LT+N++ +D C A N G + + GK D+ PP
Sbjct: 4900 -DGSCSLTVNESTMSDE-GIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKF 4957
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLK 455
S+ ++ + ++ C P P + W +G LI++ R +N+ + L +K
Sbjct: 4958 ILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIK 5017
Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+ D GTY CVA++ +G + +D + +
Sbjct: 5018 NATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGV 5054
Score = 91.5 bits (217), Expect = 3e-18
Identities = 110/474 (23%), Positives = 186/474 (39%), Gaps = 49/474 (10%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
+P ++WYK + ++H G + A + D Y +N+ G S
Sbjct: 4258 APVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSS 4317
Query: 98 NATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
A V VL+ L+ + Q V L+ + G P+ + W KNGQ L D D
Sbjct: 4318 AALTVVKPNVLKIVDGLKDVDVEEPQ--PVELK-VKVEGIPKV-IKWYKNGQELKPDADG 4373
Query: 156 RM--HLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--- 208
+ G +L I ++++D G Y+ + N G S +H+K + P
Sbjct: 4374 FKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSV---VHVKSAKSSEPTSG 4430
Query: 209 -------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLR 258
+D + G +T QC + G+P P+V+W + + RV + +LR
Sbjct: 4431 ANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLR 4490
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARF 312
+ + +D G+Y A+N G+ ++ +TV + P + + G+ F
Sbjct: 4491 IRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEF 4550
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
G P+PT+ W + G P D+ + DG LTI D + D T+ C
Sbjct: 4551 NVKVRGLPKPTLQWFLNG-----IPIKFDDRITLDDMADGNYCLTIRDVREEDF-GTLKC 4604
Query: 373 SAVNYAGSSFV-------RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
A N G+ G + DD R PP ++ +P+ C P
Sbjct: 4605 IAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANP 4664
Query: 426 EPIIAWYFEGEALIQNHRRNVTN--DGTLVLK--DLDKSDSGTYTCVASSRHGK 475
+ W+ +G+ + + N DG +K ++SD G Y CVA + G+
Sbjct: 4665 TAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQ 4718
Score = 90.2 bits (214), Expect = 8e-18
Identities = 118/480 (24%), Positives = 194/480 (40%), Gaps = 35/480 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + + G + L
Sbjct: 3760 PEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEI 3816
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ ++ D Y +N G A S +A L V + E + +G VL+
Sbjct: 3817 PNAQL-DDTADYKVVVSNDAGDADS-SAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVET 3874
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAG- 187
+ E + W KNG+ + D DG N LVI DA DA Y+ + + G
Sbjct: 3875 NKKPKE--IKWYKNGKEIT-PSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGN 3931
Query: 188 TRESAIA-TLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242
T +S+ A T+K+ K P +I G ED V GS + + G P V W ++ G
Sbjct: 3932 TADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSP-KTVKWYKNGKELPGA 3990
Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP- 299
+++ +DD L + + ++ D G+Y E N G+ ++SG +TV +P L P
Sbjct: 3991 AAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-EPKITFLKPL 4049
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
++ G A F+ +P + W G I P ++ D L I
Sbjct: 4050 KDQSITEGENAEFSVETNTKPR-IVKWYKNGQE--IKP---NSRFIIEQKTDTKYQLVIK 4103
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
+ ++D+ +T N AG + +LTV I+ G +Q + + VF
Sbjct: 4104 NAVRDDA-DTYKIVLENTAGEAESSAQLTVKKAKAGLCKIV-KGLEDQVVAKGAKMVFEV 4161
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTN-DGT---LVLKDLDKSDSGTYTCVASSRHGK 475
PE + W + + + D T L++ D D+G YT + GK
Sbjct: 4162 KIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGK 4220
Score = 88.2 bits (209), Expect = 3e-17
Identities = 79/284 (27%), Positives = 116/284 (40%), Gaps = 10/284 (3%)
Query: 30 TLNCRA--GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
TL C+ G P+P ++WY G LV + I A G++ ++ HG G C A
Sbjct: 1939 TLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMK-IHGVTADMTGKIKCVA 1997
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + VA + EF +GDT+ L + G PEP V W NG+
Sbjct: 1998 YNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAV-LLGEPEPVVSWYVNGK 2056
Query: 148 TLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYL 204
L + ++H G + I+D +G+ C A N G T E+ + L P
Sbjct: 2057 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2116
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVI 263
+ +V A+TG+ V + GDP P + W + N L + D S N
Sbjct: 2117 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2176
Query: 264 LAD--EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
D GE C+AEN G VS + + Y + S + E
Sbjct: 2177 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAE 2220
Score = 86.6 bits (205), Expect = 9e-17
Identities = 98/460 (21%), Positives = 167/460 (36%), Gaps = 28/460 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P D V + G P P++ W G V + ++ G +
Sbjct: 1725 EVPKFTTNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTI 1784
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVL 127
+ AG CEATN G+ + R+ L V + + F E + +G+ ++
Sbjct: 1785 EIS-AVTPEQAGELSCEATNPVGS-KKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLM 1842
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNA 185
+ P+P + W K+G + DG ++ + G+L + + D GR A +
Sbjct: 1843 DAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESE 1902
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV--TFQCR--VGGDPLPDVLW----RR 237
G E + + + +P + +A + T +C+ + GDP P V W +
Sbjct: 1903 FGVAECSASLGVVKGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQL 1962
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
+ + + ++++ V G+ C A N G VS G L V P +
Sbjct: 1963 VCATEDTEISNANGVY--TMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEF 2020
Query: 298 SPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+ G+ + G PEP + W V G + K H+ G
Sbjct: 2021 ETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKK---LEESQNIKIHSEK---GTYT 2074
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+TI D D +VC A+N G + L V + PP SN +
Sbjct: 2075 VTIKDITC-DYSGQVVCEAINEYGKATSEATLLVLPRGE--PPDFLEWLSNVRARTGTKV 2131
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVL 454
V P+P + WY + ++ + VT+D T L
Sbjct: 2132 VHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTL 2171
Score = 86.2 bits (204), Expect = 1e-16
Identities = 80/296 (27%), Positives = 130/296 (43%), Gaps = 31/296 (10%)
Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAG-GLFFLRATHG 74
+PL+V + L G+P P + W+K + + ++H G G L
Sbjct: 2849 RPLEVR--EQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQA 2906
Query: 75 RVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R D GVY C+ATN G A++ N + + F + + QG L +
Sbjct: 2907 R-GEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAEL-VVRVE 2964
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGN----LVIQDARQTDAGRYQCIARNAAG 187
G PEP V W K+G + D H+++ G N LVI+D D G+Y C A N AG
Sbjct: 2965 GKPEPEVKWFKDGVPIAIDNQ---HVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAG 3021
Query: 188 TRESAIATLKI-----------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
++ + LKI +KP I ++ A G +V +C+V + P + +
Sbjct: 3022 -KDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFF 3080
Query: 237 RSAGGGNMPLG-RVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ + +++VL+DG+++L N D G Y CEA N G + + L +
Sbjct: 3081 KNDQPVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3136
Score = 81.0 bits (191), Expect = 5e-15
Identities = 123/534 (23%), Positives = 198/534 (37%), Gaps = 37/534 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP ++ + V + A C+ G+ P ++W+K G + D
Sbjct: 3377 APGFFKELSAIQVKETETAKFECKVSGT-KPDVKWFKDGTPLKEDKRVHFESTDDGTQRL 3435
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D G Y E +N G A S+ V + + QG ++L +
Sbjct: 3436 VIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLS-V 3494
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCI-ARNAAG 187
G P+ V W K +T+ +++ V L I+ A +D G Y+ + + ++
Sbjct: 3495 EVEGKPK-TVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFS 3553
Query: 188 TRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
SA T+ KI + P G D G+ + + + G P DV W ++ G
Sbjct: 3554 VESSATVTVTKAAEKISL-PSFKKGLADQSVPKGTPLVLEVEIEGKP-KDVKWYKN--GD 3609
Query: 243 NMPLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
+ G+V+ L +G RL + D GEYS A N G + + + V P I
Sbjct: 3610 EIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLV 3669
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
V+ G A F G P + W G I ++D DG L I +
Sbjct: 3670 PTTVKQGETATFNVKVKG-PVKGVKWYKNGKE--IPDAKTKDN------GDGSYSLEIPN 3720
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDD--DRPPPIITNGPSNQTLPIKSMAVF 417
D+ + V + N AG + LTV +DD D+ P I +G T+ A F
Sbjct: 3721 AQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATF 3779
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475
+ P + WY G+ I N + DG +L + + D+ Y V S+ G
Sbjct: 3780 N-VKVKGPVKQVKWYKNGKE-IPNAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGD 3837
Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
S AL V P I + + + +P + + W +N K
Sbjct: 3838 ADSSAALTVKL---PGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGK 3888
Score = 80.6 bits (190), Expect = 6e-15
Identities = 102/403 (25%), Positives = 167/403 (41%), Gaps = 33/403 (8%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA-GGL 66
G+AP + D + + ++ + P P I W K GV + SD H I+ G
Sbjct: 1820 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 1879
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQG 122
L ++ D G +A + +G A +A+L V + + F+ + +G
Sbjct: 1880 LKLSILQTKLE-DKGRITIKAESEFGVAEC-SASLGVVKGRPMAKPAFQSDIAPINLTEG 1937
Query: 123 DTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQC 180
DT LEC L G P P V W Q + D+ + +G + I G+ +C
Sbjct: 1938 DT--LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKC 1995
Query: 181 IARNAAGTRESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+A N AG S LK+ + P + T D + G ++ + + G+P P V W
Sbjct: 1996 VAYNKAG-EVSTEGPLKV-VAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2053
Query: 238 SAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---D 291
+ G +K+ + ++ + ++ G+ CEA N G ++ L V +
Sbjct: 2054 N-GKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGE 2112
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP ++V +G TG P+P++ W + N+ I+ + D Y T V D
Sbjct: 2113 PPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYIN-NKEIL----NSDLY--TIVTD 2165
Query: 352 GVT-VLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSD 392
T LTIN + + I+C A N AG S +T TSD
Sbjct: 2166 DKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTANMITYTSD 2208
Score = 75.8 bits (178), Expect = 2e-13
Identities = 99/334 (29%), Positives = 140/334 (41%), Gaps = 50/334 (14%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSI 60
D + G+AP PL + A+ T C G+P P+I+W K G+ + SD +
Sbjct: 5276 DSSIREGKAPGFTT-PLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKME 5334
Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-------EEFRLE 113
A G L + S+ G + C ATN +GTA S A L + R E E
Sbjct: 5335 AAADGTQRLILSDVTFLSE-GYFRCVATNEHGTA-STKAELVIEGDRTIGSRPLPEVNGE 5392
Query: 114 PES----------KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--- 160
PE S VV + G P P V W K+GQ ++ DG ++
Sbjct: 5393 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 5452
Query: 161 DGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---------PE 209
+ G +LVI +A D G Y A N G+ ++ +L I I+P I P
Sbjct: 5453 ERGIHHLVIVNASPDDEGEYSLEATNKLGSAKTE-GSLNI-IRPRHIADADERGGMPFPP 5510
Query: 210 DVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG----SLR 258
V Q + F C V G P P+V W + G +P GR+K+ G +L
Sbjct: 5511 GFVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHN-GKKIVPGGRIKIQSCGGGSHALI 5569
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ + L D GEY A+NS G+ S+S L V P
Sbjct: 5570 ILDTTLEDAGEYVATAKNSHGSASSSAVLDVTVP 5603
Score = 75.4 bits (177), Expect = 2e-13
Identities = 74/289 (25%), Positives = 114/289 (39%), Gaps = 23/289 (7%)
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DG--SLRLDNVILADEGEYSCE 273
SS +V G PLPD+ W + + D DG ++ +D V + D G Y+C
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 274 AENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
A N G S S + V PP+ + G+V F C G PEP + W
Sbjct: 623 ATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWL 682
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
V+ R + +DG T L I D +D+ N GS + +
Sbjct: 683 VDDQPL-------RPSHDFRLQYDGQTAKLEIRDAQPDDT-GVYTVKIQNEFGSIESKAE 734
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHR- 443
L V +D D+ + + + ++ T P P I W+ G+ L ++ +
Sbjct: 735 LFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKV 794
Query: 444 RNVTNDGTLVL--KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+ ++ DG +L KD+ + G TC S+R G G L V P P
Sbjct: 795 KFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP 843
Score = 74.5 bits (175), Expect = 4e-13
Identities = 119/491 (24%), Positives = 192/491 (39%), Gaps = 40/491 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFL 69
P II+ D V+ P L GSP ++WYK G + ++I ++
Sbjct: 3948 PKIIKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV 4006
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLE 128
V D G Y E N G+A N++ + V + L+P QS +G+ E
Sbjct: 4007 LEIPSSVVEDTGDYKVEVANEAGSA---NSSGKITVEPKITFLKPLKDQSITEGENA--E 4061
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARN 184
+ V W KNGQ + +SR + + LVI++A + DA Y+ + N
Sbjct: 4062 FSVETNTKPRIVKWYKNGQEI--KPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4119
Query: 185 AAGTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
AG ES+ K L + G ED V G+ + F+ ++ G+P DV W R A
Sbjct: 4120 TAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEP-EDVRWLRDANV 4178
Query: 242 GNMPLGRV-KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
+ + + +DD + RL + L D GEY+ E N G + V + P I
Sbjct: 4179 ISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRG 4238
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
++ + G+ F + P + W N I P A + L I
Sbjct: 4239 LENIEIPEGDDDVFKVEVSA-PVRQVKW--YKNDQEIKP---NSHLEAKKIGPKKYELAI 4292
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N +D + V + N AG LTV + I +G + +
Sbjct: 4293 NRAQLDDGADYKVVLS-NAAGDCDSSAALTVVKPNVLK---IVDGLKDVDVEEPQPVELK 4348
Query: 419 CTAICTPEPIIAWYFEGEAL------IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
P+ +I WY G+ L + + + + +L + KSD G Y V +
Sbjct: 4349 VKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGND 4407
Query: 473 HGKYVWSGALL 483
G+ V+SG+++
Sbjct: 4408 KGE-VYSGSVV 4417
Score = 72.5 bits (170), Expect = 2e-12
Identities = 87/393 (22%), Positives = 159/393 (40%), Gaps = 30/393 (7%)
Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
V+ +F + + ++ +G + V EC+ P + W K+G+ + R+ G
Sbjct: 2244 VMAPKFITKIKDTKAKKGHSAVFECVVP-DTKGVCCKWLKDGKEIELIARIRVQTRTGPE 2302
Query: 165 ------LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIK------PYLITGPED 210
LV+ + DAG+Y CI N AG T E+ + ++ K P I +D
Sbjct: 2303 GHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQD 2362
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
+T V +C+V G+P P V W V+ ++ + + + L+ +G+
Sbjct: 2363 KTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTITSSELSHQGK 2422
Query: 270 YSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
Y+C AEN+ G +LTV + P + + G +C+ G P+P + +
Sbjct: 2423 YTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYS 2482
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVT--VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
T + ++ A T + I+ K D + A N G++ K
Sbjct: 2483 FSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDI-VSYKAIATNSIGTATSTSK 2541
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NH-- 442
+T + P+ G ++ K + P + W+ + + + + NH
Sbjct: 2542 ITTKVE----APVFEQGLKKTSVKEKEEIKME-VKVGGSAPDVEWFKDDKPVSEDGNHEM 2596
Query: 443 RRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
++N T TLV+K +D+G YT AS+ G
Sbjct: 2597 KKNPETGVFTLVVKQAATTDAGKYTAKASNPAG 2629
Score = 72.5 bits (170), Expect = 2e-12
Identities = 119/493 (24%), Positives = 193/493 (39%), Gaps = 42/493 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + G + L
Sbjct: 3662 PEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD--NGDGSYSLEI 3718
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSA------QGDT 124
+ +V DA Y +N G A S +A L V + + + +++PE QG+T
Sbjct: 3719 PNAQVE-DAADYKVVVSNDAGDADS-SAALTVKLADDGKDKVKPEIVSGLIPTTVKQGET 3776
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ +G P V W KNG+ + + ++ + +L I +A+ D Y+ + N
Sbjct: 3777 ATFN-VKVKG-PVKQVKWYKNGKEIP-NAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSN 3833
Query: 185 AAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
AG +S+ A T+K+ ++ G ED G Q P ++ W ++ G
Sbjct: 3834 DAGDADSSAALTVKLP-GIAIVKGLEDAEVPKGKKAVLQVETNKKP-KEIKWYKN-GKEI 3890
Query: 244 MPLGRVKVLDDGSLRLDNVILA----DEGEYSCEAENSVG-AVSASGYLTVYDP---PSI 295
P + + DG + VI D EY + G +S LTV P P I
Sbjct: 3891 TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKI 3950
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
V G+ + +G P+ T+ W G PG + + D V
Sbjct: 3951 IKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKE---LPGAAAKTIKIQKIDDNKYV 4006
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L I + D+ + V N AGS+ GK+TV P +Q++ A
Sbjct: 4007 LEIPSSVVEDTGDYKV-EVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGENA 4060
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
F P I+ WY G+ + N R + LV+K+ + D+ TY V +
Sbjct: 4061 EFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4119
Query: 472 RHGKYVWSGALLV 484
G+ S L V
Sbjct: 4120 TAGEAESSAQLTV 4132
Score = 70.1 bits (164), Expect = 9e-12
Identities = 133/588 (22%), Positives = 217/588 (36%), Gaps = 54/588 (9%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
S AP ++ D TV + A G+P+P + W+ G + + + A
Sbjct: 942 SRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHD 1001
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-------SKQSA 120
+ AG C A N+ G ++ + VL E + +P K
Sbjct: 1002 HKLTIDSAQY--AGTVLCRAENAVGRFETK---ARLVVLAPEKQKKPPKFVEILVDKTET 1056
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179
+TVV E + G P+P V W G+ L + DG + I++ + DAG +
Sbjct: 1057 VDNTVVFE-VRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115
Query: 180 CIARNAAGTRESAIATLKIHIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
+A N+ G+ E+ A L + KP+ P + + GS F G PLP W
Sbjct: 1116 AVATNSEGSDETK-AKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWS 1174
Query: 237 RSA-----GGGNMPLGRVKVLDDGS--LRLDNVILADEGEY---SCEAENSVGAVSASGY 286
+ G + R + DG+ L +D E + S AEN++GA
Sbjct: 1175 VNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQ 1234
Query: 287 LTV--YDPPSINLSPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
LT+ PP+ L+ + V ++A F E W ++G G++
Sbjct: 1235 LTIEPKKPPAPKLTRDLKLQTVNKTDLAHFEVVVEHATE--CKWFLDGKEITTAQGVTVS 1292
Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIIT 401
K D DT S T+ A N AGS + +L V + + P T
Sbjct: 1293 K------DDQFEFRCSIDTTMFGS-GTVSVVASNAAGSVETKTELKVLETPKETKKPEFT 1345
Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-----NDGTLVLKD 456
+ + + + I P+ WY G L+++ + VT N +L++
Sbjct: 1346 D--KLRDMEVTKGDTVQMDVIALHSPLYKWYQNGN-LLEDGKNGVTIKNEENKSSLIIP- 1401
Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516
+ DSG T AS+ G S L V+ P I V ++ T ++
Sbjct: 1402 -NAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKSV-TIKETETAEFKATIS 1459
Query: 517 D-TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
+ T+ W+ N KI S ++ TL +N G V +
Sbjct: 1460 GFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKV 1507
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 15/207 (7%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG---QTLLFDGDSRMHLVDGGN--LVIQD 169
E + A+ DT+ + L G P+P++ WK G T +++ G L I
Sbjct: 5777 EKRYCAENDTLTI-VLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITG 5835
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
+ + G+YQC A+N G + I + + +P I + + + RV G+P
Sbjct: 5836 FSKENVGQYQCFAKNDYGDAQQNIM-VDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEP 5894
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P++ W + + R+K + DG SL +++ + D G YSC A N G + S
Sbjct: 5895 FPELKWMKE-WRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 5953
Query: 286 YLTVY---DPPSINLSPNSVNVESGNV 309
+TV D + L V +ES V
Sbjct: 5954 TVTVEAEGDYNDVELPRRRVTIESRRV 5980
Score = 61.7 bits (143), Expect = 3e-09
Identities = 66/257 (25%), Positives = 93/257 (36%), Gaps = 16/257 (6%)
Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
+VG ++S T P S V A C G P P + W+ EG
Sbjct: 3161 TVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEV--- 3217
Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD--- 393
MS + A DG LT ++ + D+ C A N GS++ G + VT +
Sbjct: 3218 -EMSA-RVRAEHKDDGTLTLTFDNVTQADA-GEYRCEAENEYGSAWTEGPIIVTLEGAPK 3274
Query: 394 -DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DG 450
D P + + AV P+P + WY GE L + R + N DG
Sbjct: 3275 IDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDG 3334
Query: 451 T--LVLKDLDKSDSGTYTCVASSRHGKYVWSG-ALLVDSPINPNIHFFRAADVSSLPGPP 507
T L + + D Y C AS+ G VWS L V P FF+ +
Sbjct: 3335 TQRLTVTNAKLDDMDEYRCEASNEFGD-VWSDVTLTVKEPAQVAPGFFKELSAIQVKETE 3393
Query: 508 TKPITHNVTDTSVTLSW 524
T V+ T + W
Sbjct: 3394 TAKFECKVSGTKPDVKW 3410
Score = 60.5 bits (140), Expect = 7e-09
Identities = 89/376 (23%), Positives = 149/376 (39%), Gaps = 27/376 (7%)
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
D +G +A NAAG+ E+ LK+ P PE VT V D
Sbjct: 1304 DTTMFGSGTVSVVASNAAGSVETK-TELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMD 1362
Query: 229 --PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVGAVSA 283
L L++ G + G+ V ++I+ D G+ + EA N VG+ +
Sbjct: 1363 VIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSES 1422
Query: 284 SGYLTVYDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
S LTV P P + P SV ++ A F T +G P PT+ W++ N I+
Sbjct: 1423 SAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTI--NEKIV----E 1476
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP--PP 398
+ T + V L I++ K + T+ +A N AG + L V + P
Sbjct: 1477 ESRTITTIKTEDVYTLKISNA-KIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 1535
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGT--LVL 454
+T+ +++ P++ +P ++W G+ L ++ V + DGT + +
Sbjct: 1536 QLTDKVADEGEPLRWNLELDGP---SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTI 1592
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514
+ SGT T A + G+ S + V+ N F +A + +
Sbjct: 1593 AEAKPEMSGTLTAKAKNAAGECETSAKVTVNGG-NKKPEFVQAPQNHETTLEESVKFSAI 1651
Query: 515 VTDTSV-TLSWSQNNK 529
VT + ++W NNK
Sbjct: 1652 VTGKPMPNVTWYLNNK 1667
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 12/171 (7%)
Query: 24 ARHQPATLNCRAGGSPSPAIRW-YKG-GVLVVSDTHR-SILPAGGLFFLRATHGRVHSDA 80
A + T+ G P P I+W ++G + S T + + GG A G +
Sbjct: 5782 AENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENV 5841
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N YG A+ +N + +A R F ++P ++ + + G P P +
Sbjct: 5842 GQYQCFAKNDYGDAQ-QNIMVDLAT-RPNF-IQPLVNKTFSSAQPMRMDVRVDGEPFPEL 5898
Query: 141 YWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG 187
W K + ++ SR+ V G +L+I D D+G Y C+A N AG
Sbjct: 5899 KWMKEWRPIV--ESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAG 5947
Score = 41.1 bits (92), Expect = 0.005
Identities = 40/187 (21%), Positives = 67/187 (35%), Gaps = 12/187 (6%)
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT-AVFDGVTVLTINDTDKNDSRN 368
A+ TG P P + W + + + D+ H + DG +TI+ D+
Sbjct: 565 AKMCLKVTGYPLPDITWYKDDVQ------LHEDERHTFYSDEDGFFAMTIDPVQVTDT-G 617
Query: 369 TIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
C A N G + V + + PP ++ + F C PEP
Sbjct: 618 RYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEP 677
Query: 428 IIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
+ W + + L +H + DG L ++D D+G YT + G L V
Sbjct: 678 ELVWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFV 737
Query: 485 DSPINPN 491
+ + N
Sbjct: 738 QADPDKN 744
Score = 39.9 bits (89), Expect = 0.011
Identities = 21/83 (25%), Positives = 36/83 (43%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ ++ T + QP ++ R G P P ++W K +V + + G
Sbjct: 5867 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 5926
Query: 72 THGRVHSDAGVYWCEATNSYGTA 94
+ + D+G+Y C A N G A
Sbjct: 5927 INDPMWRDSGIYSCVAVNDAGQA 5949
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P P + W E ++++ R DG +L++ D DSG Y+CVA + G+ S
Sbjct: 5894 PFPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 5953
Query: 481 ALLVDS 486
+ V++
Sbjct: 5954 TVTVEA 5959
>AF003131-4|AAB54132.2| 6632|Caenorhabditis elegans Uncoordinated
protein 89, isoform a protein.
Length = 6632
Score = 146 bits (354), Expect = 8e-35
Identities = 178/689 (25%), Positives = 281/689 (40%), Gaps = 110/689 (15%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAG 64
VT+ + P + DV QP L C+ SP P + WYK G +V SD + L
Sbjct: 5695 VTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPD 5754
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLREEFR--- 111
G+ L V+ D G+Y ATN GTA+ R++ + R+ F
Sbjct: 5755 GVATLLIP-SCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANK 5813
Query: 112 ----LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-- 164
+EP E+ + + + L C G P+P + W K+G+ + G R+ L++ +
Sbjct: 5814 APKLMEPLENIRIPEKQSFRLRC-KFSGDPKPTIKWFKDGERVFPYG--RLQLIESPDGV 5870
Query: 165 --LVIQDARQTDAGRYQCIARNAAGTRESA--IATLKIHIKPYLI------------TGP 208
LV+ A + DAG Y+C+A N G+ ++ + ++ KP I T P
Sbjct: 5871 CELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTP 5930
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL--DNVI 263
+ A+ G SVTF+C G+P P + W + G ++K+ DG+ RL +V
Sbjct: 5931 LTIRRAKPGDSVTFECLPFGNPFPSIKWLKD-GLELFSDEKIKMEAAADGTQRLILSDVT 5989
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDP--------PSINLSPN-----------SVNV 304
EG + C A N G S L + P +N P ++++
Sbjct: 5990 FLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMSI 6049
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
GNV ATG P PT+ W +G + I+ G + T G+ L I + +
Sbjct: 6050 HEGNVVEMIVCATGIPTPTVKWYKDG-QEIVGDGPDGKRVIFTDE-RGIHHLVIVNASPD 6107
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLT------VTSDDDRP----PPIITNGPSNQTLPIKSM 414
D A N GS+ G L + D+R PP N+ +
Sbjct: 6108 D-EGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMP 6166
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVAS 470
+F C + P P + W+ G+ ++ R + + G L++ D D+G Y A
Sbjct: 6167 TIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATAK 6226
Query: 471 SRHGKYVWSGALLVDSPINPNIHF---------------FRAADVSSLPGPPTK-PITHN 514
+ HG S L V P +I F F+ + +SLP PP + P
Sbjct: 6227 NSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKKLNTASLPTPPDRGPFIKE 6286
Query: 515 VTDTSVTLSWSQNNKIGSS-SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
VT +TLSW + + Y +E+ RE + W ++ + +
Sbjct: 6287 VTGHYLTLSWIPTKRAPPRYPQVTYVIEI--REL--------PEKQWSLLEYNIPEPVCK 6336
Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVS 602
V++L G +Y F VR EN +G+S PSP S
Sbjct: 6337 VRNLELGKSYQFRVRAENIYGISDPSPAS 6365
Score = 140 bits (339), Expect = 5e-33
Identities = 139/499 (27%), Positives = 208/499 (41%), Gaps = 62/499 (12%)
Query: 28 PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-PAGGLFFLRATHGRVHSDAGVYWCE 86
P + C +P+ + W+K G + H I G ++ SD GVY C
Sbjct: 5293 PMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFE-ESDIGVYMCV 5351
Query: 87 ATNSYGTARSRNATLHVAVL-------REEF--RLEP--ESKQSAQGDTVVLECLPPRGS 135
A N G A ++ AT V +L R E+ ++ P E K G + L C
Sbjct: 5352 AVNELGQAETQ-ATYQVEILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSC-KVDAI 5409
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGT-RESA 192
P +V W K+G L D + + + G L I D+ + D G Y+C+A NA GT S
Sbjct: 5410 PRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSC 5469
Query: 193 IATLKI---HIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGN 243
+K+ +K P+ G D+ A G S T +C V GDP P++ W R+ N
Sbjct: 5470 SVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRN 5529
Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY----------- 290
P ++ DG SL ++ ++DEG Y CEAEN+ G V
Sbjct: 5530 GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKM 5589
Query: 291 ---DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
PP L + ++V GNV C TG P P++ WS +G I SR ++ +
Sbjct: 5590 DEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLI---EDSRFEW-SN 5645
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSN 406
GV L I + +D T C A N GS+ K V DD ++T + P
Sbjct: 5646 EASKGVYQLRIKNATVHD-EGTYRCVATNENGSATT--KSFVRMDDGLGSGVVTASQPPR 5702
Query: 407 QTLPIKSMAV-------FPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDG--TLVLK 455
TL + + C +P P + WY +G + + R + + DG TL++
Sbjct: 5703 FTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIP 5762
Query: 456 DLDKSDSGTYTCVASSRHG 474
D G Y +A++ G
Sbjct: 5763 SCVYDDDGIYRVIATNPSG 5781
Score = 139 bits (336), Expect = 1e-32
Identities = 142/521 (27%), Positives = 221/521 (42%), Gaps = 71/521 (13%)
Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I PL D TV QP L+C+ P ++ WYK G+ + +D+ SI A +
Sbjct: 5385 INPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIN 5444
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---------QSAQGDT 124
D G Y C ATN++GT + + +++V V ++E + E E + +GD+
Sbjct: 5445 DSTEEDIGAYRCVATNAHGTINT-SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDS 5503
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGG-NLVIQDARQTDAGRYQCI 181
L+C G P P + W +NGQ LL +G + DG +L + ++ +D G Y+C
Sbjct: 5504 FTLKC-AVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561
Query: 182 ARNAAG-TRESAIATLKIHI----KPYLITGP--------EDVVAQTGSSVTFQCRVGGD 228
A NA G + A A +++ + KP + G D+ G+ + +C+V G
Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGL 5621
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVS- 282
P P V W + GG + R + ++ S LR+ N + DEG Y C A N G+ +
Sbjct: 5622 PNPSVKWSKD-GGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATT 5680
Query: 283 ----------ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
SG +T PP L V G + C P P M W +G
Sbjct: 5681 KSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG-- 5738
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--- 389
I+ P D+ + DGV L I +D V A N +G++ +G TV
Sbjct: 5739 AIVTPS---DRIQISLSPDGVATLLIPSCVYDDDGIYRVI-ATNPSGTAQDKGTATVKKL 5794
Query: 390 --------TSD----DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
++D D P + N +P K C P+P I W+ +GE
Sbjct: 5795 PRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGER 5854
Query: 438 LIQNHRRNV--TNDGT--LVLKDLDKSDSGTYTCVASSRHG 474
+ R + + DG LV+ + D+G Y CVA + +G
Sbjct: 5855 VFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYG 5895
Score = 136 bits (328), Expect = 1e-31
Identities = 127/499 (25%), Positives = 210/499 (42%), Gaps = 32/499 (6%)
Query: 7 TSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PA 63
T EAP + EQ L T V + + + GGS +P + W+K V D + + P
Sbjct: 3184 TKVEAP-VFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDDKPVSEDGNHEMKKNPE 3241
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQG 122
G+F L +DAG Y +A+N GTA S A + ++ + F E + +
Sbjct: 3242 TGVFTLVVKQAAT-TDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKIN 3300
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQ 179
+T L + +G P+P+V W K+GQ + D + V+G ++ I+DAR D+G+Y
Sbjct: 3301 ETATLS-VTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYA 3359
Query: 180 CIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
C A N AG E+ A +K + P + + + S T +V G P P V W +
Sbjct: 3360 CRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFK 3419
Query: 238 SAGGGNMP----LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYD- 291
++ + + + SL +++ D G YSC A N G A++ + + + D
Sbjct: 3420 DDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS 3479
Query: 292 -PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
PP + V T G P P + W + ++ I + A
Sbjct: 3480 IPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEW-FKDDKPI---NIDNSHIFAKDEG 3535
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G LTI + + C A N AG + + V + + P + G +
Sbjct: 3536 SGHHTLTIKQA-RGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP--LFVQGLKPYEVE 3592
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTY 465
A PEP + W+ +G + +++ + G TLV+KD + +D G Y
Sbjct: 3593 QGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKY 3652
Query: 466 TCVASSRHGKYVWSGALLV 484
TC A+++ GK G L +
Sbjct: 3653 TCQATNKAGKDETVGELKI 3671
Score = 135 bits (327), Expect = 2e-31
Identities = 129/483 (26%), Positives = 199/483 (41%), Gaps = 34/483 (7%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + + G P P I WYK V + D + FF +D G Y C AT
Sbjct: 565 AKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMAT 624
Query: 89 NSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
N YG A S +A V + +E F + K+ +GD + EC G PEP + W
Sbjct: 625 NEYGQA-STSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFEC-EVEGWPEPELVWL 682
Query: 144 KNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL----- 196
+ Q L D R+ DG L I+DA+ D G Y +N G+ ES
Sbjct: 683 VDDQPLRPSHDFRLQ-YDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADP 741
Query: 197 -KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDD 254
K H+ P E V G V F+ + GDP P+++W + G +VK + +D
Sbjct: 742 DKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFIN-GKPLSESEKVKFISED 800
Query: 255 G--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNV 309
G L + +V +G +C+ N +G+ S G L V PP+ N V+ +
Sbjct: 801 GICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKST 860
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
F +G PEPT+ +++ G + ++ DG ++I +T +
Sbjct: 861 VVFEVDVSGWPEPTLTFTLCGKEL-----KNGEEGVEIVGHDGFYRISIPNTSMDKHDGE 915
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDD--RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
IV A N G++ R +LTV +++ R P +QT+ AVF T P P
Sbjct: 916 IVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNP 975
Query: 428 IIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
+ W+ G + Q + N + D +GT C A + G++ L+V
Sbjct: 976 EVTWFINGHKMDQGSPGVKIEAHNHDHKLTID-SAQYAGTVLCRAENAVGRFETKARLVV 1034
Query: 485 DSP 487
+P
Sbjct: 1035 LAP 1037
Score = 126 bits (303), Expect = 1e-28
Identities = 139/544 (25%), Positives = 222/544 (40%), Gaps = 78/544 (14%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GE P+ + +D+ R TL C G P P I+WY+ G L+ + I +
Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC 5543
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREE-----------FRLEPE 115
+ SD G+Y CEA N++G A+++ AT HV A+ + E F LE
Sbjct: 5544 SLTVNESTMSDEGIYRCEAENAHGKAKTQ-ATAHVQMALGKTEKPKMDEGKPPKFILELS 5602
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-----LVIQDA 170
+ G+ + LEC G P P+V W K+G L+ DSR + + L I++A
Sbjct: 5603 DMSVSLGNVIDLEC-KVTGLPNPSVKWSKDGGPLI--EDSRFEWSNEASKGVYQLRIKNA 5659
Query: 171 RQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPE---------DVVAQTGSSVT 220
D G Y+C+A N G+ + + + + ++T + DV G +
Sbjct: 5660 TVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLK 5719
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDG--SLRLDNVILADEGEYSCEAEN 276
+C+V PLP+++W + G P R+++ DG +L + + + D+G Y A N
Sbjct: 5720 LECKVDASPLPEMVWYKD-GAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATN 5778
Query: 277 SVGAVSASGYLTVYDPP--------------SINLSP------NSVNVESGNVARFTCTA 316
G G TV P N +P ++ + R C
Sbjct: 5779 PSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKF 5838
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
+G P+PT+ W +G R +FP + DGV L ++ + D+ C A N
Sbjct: 5839 SGDPKPTIKWFKDGER--VFP---YGRLQLIESPDGVCELVVDSATRQDA-GGYRCVAEN 5892
Query: 377 YAGSSFVRGKLTVTSDDDRPPPI---ITNGPS-NQTLPIK-------SMAVFPCTAICTP 425
GS+ + V D +P I I G + T P+ F C P
Sbjct: 5893 TYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNP 5952
Query: 426 EPIIAWYFEGEALIQNH--RRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P I W +G L + + DGT L+L D+ G + CVA++ HG
Sbjct: 5953 FPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 6012
Query: 482 LLVD 485
L+++
Sbjct: 6013 LVIE 6016
Score = 124 bits (298), Expect = 5e-28
Identities = 126/498 (25%), Positives = 203/498 (40%), Gaps = 46/498 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLF 67
E P + + + V ++ ATL+ G P P++ W K G V +D+ I + G +
Sbjct: 3284 EKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSY 3343
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEF--RLEPESKQSAQGDT 124
+ R+ D+G Y C ATN G A++ N + ++ EF +L P + + T
Sbjct: 3344 SITIKDARLE-DSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTT 3402
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCI 181
+ ++ + G+PEP+V W K+ + D + V +L I DARQ D G Y C
Sbjct: 3403 LSVKVV---GTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCR 3459
Query: 182 ARNAAG--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
ARN AG + ++ I P + + ++ + V G P+P+V W +
Sbjct: 3460 ARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDD 3519
Query: 240 GGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
N+ + D+GS L + D G Y+C+A N G + + V +
Sbjct: 3520 KPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEA 3579
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV--F 350
P VE G A G+PEP + W +G I D H
Sbjct: 3580 PLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAI------DNQHVIEKKGE 3633
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--------TSDDDRPPPIITN 402
+G L I DT+ D C A N AG G+L + T+++ +P +
Sbjct: 3634 NGSHTLVIKDTNNADF-GKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKP---LFI 3689
Query: 403 GPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR-NVTNDGT--LVLKDL 457
P +T ++ V C P I ++ + + I H + V DG L +++
Sbjct: 3690 EPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNA 3749
Query: 458 DKSDSGTYTCVASSRHGK 475
K D G Y C A + GK
Sbjct: 3750 KKEDVGAYRCEAVNVAGK 3767
Score = 112 bits (270), Expect = 1e-24
Identities = 127/493 (25%), Positives = 204/493 (41%), Gaps = 39/493 (7%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGG 65
T AP +E TV Q A L C+ G P P I+W K G V +S R+ G
Sbjct: 3812 TGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDG 3871
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---- 121
L +DAG Y CEA N YG+A + + L +++ E+ Q
Sbjct: 3872 TLTL-TFDNVTQADAGEYRCEAENEYGSAWTEGPI--IVTLEGAPKIDGEAPDFLQPVKP 3928
Query: 122 -----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTD 174
G+T VLE G P+P+V W KNG+ L ++ +D G L + +A+ D
Sbjct: 3929 AVVTVGETAVLEG-KISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDD 3987
Query: 175 AGRYQCIARNAAGTRESAIA-TLK--IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
Y+C A N G S + T+K + P + + + F+C+V G P
Sbjct: 3988 MDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECKVSGTK-P 4046
Query: 232 DVLWRRSAGGGNMPLGRV--KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYL 287
DV W + G RV + DDG+ RL ++ D+G Y E N G ++ L
Sbjct: 4047 DVKWFKD-GTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPL 4105
Query: 288 TVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
TV ++ + VNV G + G+P+ T+ W +G T+ S
Sbjct: 4106 TVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPK-TVKW-YKGTETV----TSSQTTK 4159
Query: 346 ATAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDR-PPPIITNG 403
V + L I + +D+ +V S +++ S +TVT ++ P G
Sbjct: 4160 IVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVES--SATVTVTKAAEKISLPSFKKG 4217
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDS 462
++Q++P + V P+ + WY G+ + ++ N L + D + D
Sbjct: 4218 LADQSVPKGTPLVLEVEIEGKPKD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDV 4276
Query: 463 GTYTCVASSRHGK 475
G Y+ A++ G+
Sbjct: 4277 GEYSVTAANEAGE 4289
Score = 107 bits (257), Expect = 5e-23
Identities = 120/492 (24%), Positives = 196/492 (39%), Gaps = 35/492 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P +++ P VT+ + A G P+P ++W +V + + ++ L+
Sbjct: 2075 PIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKI 2134
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLEC 129
++ ++ G A NS G S+ A L V V +F+ + K + +G+ +
Sbjct: 2135 SNAKI-EQTGTVKVTAQNSAG-QDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNL 2192
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNA 185
SP V W NGQ L + +VD G ++ I +A+ +G A+NA
Sbjct: 2193 ELDGPSPGTEVSWLLNGQPL--TKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNA 2250
Query: 186 AGTRE-SAIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
AG E SA T+ + KP + P++ SV F V G P+P+V W ++
Sbjct: 2251 AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLI 2310
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPSIN 296
+ + V S+R+ ++ G EAEN G V A+ L V + P
Sbjct: 2311 QSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFT 2370
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTV 355
+ + V+ G +FT G PEP++ W++ G P ++ DK DG
Sbjct: 2371 TNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDK-------DGEHT 2423
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I+ + + C A N GS +L V D P ++ + +
Sbjct: 2424 IEISAVTP-EQAGELSCEATNPVGSKKRDVQLAVKKVGD--APTFAKNLEDRLITEGELT 2480
Query: 416 VFPCTA-ICTPEPIIAWYFEG-EALIQNHRRNV-TNDGTLVLKDLDK--SDSGTYTCVAS 470
+ I P+P I W +G E H + V DG+L L L D G T A
Sbjct: 2481 LMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAE 2540
Query: 471 SRHGKYVWSGAL 482
S G S +L
Sbjct: 2541 SEFGVAECSASL 2552
Score = 106 bits (255), Expect = 8e-23
Identities = 116/490 (23%), Positives = 195/490 (39%), Gaps = 39/490 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP I D T + L C+ G P P + W + ++ ++ G+ +
Sbjct: 2992 KAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQES-ITVESVEGVERV 3050
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
T + S G Y C A N+ GT+++ A L V F E ++K+ + G+ +VL C
Sbjct: 3051 TITSSEL-SHQGKYTCIAENTEGTSKT-EAFLTVQGEAPVFTKELQNKELSIGEKLVLSC 3108
Query: 130 LPPRGSPEPNVYWKKNGQTLLFD----GDSRMHLV-DGGN----LVIQDARQTDAGRYQC 180
+GSP+P+V + +T + SR+ + D N +VI + D Y+
Sbjct: 3109 -SVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKA 3167
Query: 181 IARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS- 238
IA N+ GT S + T K+ P G + + + + +VGG PDV W +
Sbjct: 3168 IATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDD 3225
Query: 239 ---AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
+ GN + + +L + D G+Y+ +A N G +S V +
Sbjct: 3226 KPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEK 3285
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD- 351
P+ + V+ A + T G P+P++ W +G + D H A +
Sbjct: 3286 PTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQ------PVQTDSSHVIAKVEG 3339
Query: 352 -GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G +TI D DS C A N AG + V + PP S +
Sbjct: 3340 SGSYSITIKDARLEDS-GKYACRATNPAGEAKTEANFAVVK--NLVPPEFVEKLSPLEVK 3396
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEAL-IQN----HRRNVTNDGTLVLKDLDKSDSGTY 465
K + TPEP + W+ + + I N ++ +L + D + D G Y
Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIY 3456
Query: 466 TCVASSRHGK 475
+C A + G+
Sbjct: 3457 SCRARNEAGE 3466
Score = 104 bits (249), Expect = 4e-22
Identities = 126/505 (24%), Positives = 191/505 (37%), Gaps = 36/505 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GEAP ++ + ++ + L+C GSP P + +Y +T + +
Sbjct: 3084 GEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEH 3143
Query: 69 LRA-THGRV------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
+ TH R+ D Y ATNS GTA S T + E E K+++
Sbjct: 3144 DQTNTHWRMVISQITKEDIVSYKAIATNSIGTATS---TSKITTKVEAPVFEQGLKKTSV 3200
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGG--NLVIQDARQTDAGRY 178
+ ++ G P+V W K+ + + DG+ M + G LV++ A TDAG+Y
Sbjct: 3201 KEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKY 3260
Query: 179 QCIARNAAGTRES---AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
A N AGT ES A T + KP + + + T V G P P V W
Sbjct: 3261 TAKASNPAGTAESSAEAEVTQSLE-KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEW 3319
Query: 236 RRSAGGGNMPLGRV--KVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
+ V KV G S+ + + L D G+Y+C A N G V
Sbjct: 3320 LKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVK 3379
Query: 292 ---PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
PP + + V+ + G PEP++ W + I K A
Sbjct: 3380 NLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVG 3439
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
F LTIND + D C A N AG + + D PP T
Sbjct: 3440 SFS----LTINDARQGDV-GIYSCRARNEAGEALTTANFGIIRDS--IPPEFTQKLRPLE 3492
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG----TLVLKDLDKSDSG 463
+ + T I TP P + W+ + + + I N ++G TL +K D G
Sbjct: 3493 VREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVG 3552
Query: 464 TYTCVASSRHGKYVWSGALLVDSPI 488
YTC A++ G+ + + V I
Sbjct: 3553 VYTCKATNEAGEAKTTANMAVQEEI 3577
Score = 102 bits (245), Expect = 1e-21
Identities = 117/404 (28%), Positives = 165/404 (40%), Gaps = 33/404 (8%)
Query: 11 APYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
AP +PL D TV G P P + + G L + I+ G +
Sbjct: 842 APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYR 901
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP------ESKQSAQG 122
+ + + G +A N +GTA SR A L V EE R P E + G
Sbjct: 902 ISIPNTSMDKHDGEIVAKAQNEHGTAESR-ARLTVEQEEEESRSAPTFLKDIEDQTVKTG 960
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRY 178
+ V E RG+P P V W NG + D S ++ N L I A+ AG
Sbjct: 961 EFAVFETTV-RGNPNPEVTWFINGHKM--DQGSPGVKIEAHNHDHKLTIDSAQY--AGTV 1015
Query: 179 QCIARNAAGTRES-----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
C A NA G E+ +A K P + D ++V F+ RV G+P P V
Sbjct: 1016 LCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTV 1075
Query: 234 LWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVY 290
W G RV++ + DGS+++ N+ + D GE A NS G+ LTV
Sbjct: 1076 TWYLK-GEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134
Query: 291 DPP---SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P +L P S+ VE G+ A F+ A G P PT WSV G + +R +
Sbjct: 1135 KKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDES 1194
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAV--NYAGSSFVRGKLTV 389
V DG ++LTI+ N + S V N G+ +LT+
Sbjct: 1195 TV-DGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTI 1237
Score = 99.5 bits (237), Expect = 1e-20
Identities = 125/500 (25%), Positives = 188/500 (37%), Gaps = 54/500 (10%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA-GGLFFLRATHGRVHS 78
D V TL C G P P + W K GV++ D ++ A G LR + S
Sbjct: 5079 DTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAK-KS 5137
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPR 133
D G Y A N G+A S + + V E+ F + ++ + GD + R
Sbjct: 5138 DIGQYRVTAKNEAGSATS-DCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFN-VKVR 5195
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
G P+P + W NG + FD + + GN L I+D R+ D G +CIA+N GT E+
Sbjct: 5196 GLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDET 5255
Query: 192 AIATLK-----------IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
+ + P D G + +C V +P +V W +
Sbjct: 5256 VCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGK 5315
Query: 241 G-GNMPLGRVKVLDDGSLRLDNVIL--ADEGEYSCEAENSVG--AVSASGYLTVYD---- 291
+ ++ DG+ R+ + +D G Y C A N +G A+ + + +
Sbjct: 5316 KIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEE 5375
Query: 292 ------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
P IN V G R +C P ++ W +G P + +
Sbjct: 5376 EKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG-----LPLRADSRTS 5430
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG----SSFVRGKLTVTS-DDDRPPPII 400
DG L IND+ + D C A N G S V K+ + P
Sbjct: 5431 IQYEEDGTATLAINDSTEEDI-GAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFF 5489
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV---TNDG--TLVLK 455
T G + C P P I WY G+ L++N R V + DG +L +
Sbjct: 5490 TKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVN 5548
Query: 456 DLDKSDSGTYTCVASSRHGK 475
+ SD G Y C A + HGK
Sbjct: 5549 ESTMSDEGIYRCEAENAHGK 5568
Score = 97.5 bits (232), Expect = 5e-20
Identities = 118/443 (26%), Positives = 172/443 (38%), Gaps = 64/443 (14%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + +AP ++E ++ + Q L C+ G P P I+W+K G V ++ +
Sbjct: 5807 DVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIES 5866
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLRE----E 109
DAG Y C A N+YG+AR+ R + +RE
Sbjct: 5867 PDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPG 5926
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
F +++ GD+V ECL P G+P P++ W K+G L D +M G L++
Sbjct: 5927 FTTPLTIRRAKPGDSVTFECL-PFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLIL 5985
Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKI-------------------HIKPYLITGP 208
D G ++C+A N GT S A L I KP + G
Sbjct: 5986 SDVTFLSEGYFRCVATNEHGT-ASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGL 6044
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDD----GSLRLDNV 262
++ G+ V G P P V W + G+ P G+ + D L + N
Sbjct: 6045 YNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNA 6104
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---------NLSPNSV-NVESGNVAR- 311
DEGEYS EA N +G+ G L + P I P V +++ +V
Sbjct: 6105 SPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNH 6164
Query: 312 ----FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
F C G P P + W G + I PG R K + G L I DT D+
Sbjct: 6165 MPTIFDCLVVGHPAPEVEWFHNGKK--IVPG-GRIKIQSCG--GGSHALIILDTTLEDA- 6218
Query: 368 NTIVCSAVNYAGSSFVRGKLTVT 390
V +A N GS+ L VT
Sbjct: 6219 GEYVATAKNSHGSASSSAVLDVT 6241
Score = 96.3 bits (229), Expect = 1e-19
Identities = 125/542 (23%), Positives = 206/542 (38%), Gaps = 42/542 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLFFL 69
P ++ P + + + G P P + WY ++ + + G +
Sbjct: 2269 PEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSI 2328
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
R + + G EA N G ++ A L V E +F + +Q +G+ V
Sbjct: 2329 RIQKPLMEHN-GTIRVEAENVSGKVQA-TAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKF 2386
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAA 186
G PEP+V W NG+ + + + DG + + I AG C A N
Sbjct: 2387 TA-NVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPV 2445
Query: 187 GT--RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243
G+ R+ +A K+ P ED + G ++ P P + W + G
Sbjct: 2446 GSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKD-GVEI 2504
Query: 244 MPLGRVKVLD--DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPS 294
G K+++ DGSL+L L D+G + +AE+ G S L V P+
Sbjct: 2505 TSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPA 2564
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+N+ G+ TG P P + W + G + + + D + A +GV
Sbjct: 2565 FQSDIAPINLTEGDTLECKLLITGDPTPFVKWYI-GTQLVC---ATEDTEISNA--NGVY 2618
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKS 413
+ I+ D I C A N AG G L V + P P+ + T
Sbjct: 2619 TMKIHGVTA-DMTGKIKCVAYNKAGEVSTEGPLKVVA----PIPVEFETSLCDATCREGD 2673
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
+ PEP+++WY G+ L ++ + ++ T+ +KD+ SG C A
Sbjct: 2674 TLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAI 2733
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT---DTSVTLSWSQN 527
+ +GK LLV P ++V + G TK + H V D +L+W N
Sbjct: 2734 NEYGKATSEATLLVLPRGEPPDFLEWLSNVRARTG--TK-VVHKVVFTGDPKPSLTWYIN 2790
Query: 528 NK 529
NK
Sbjct: 2791 NK 2792
Score = 92.7 bits (220), Expect = 1e-18
Identities = 126/525 (24%), Positives = 200/525 (38%), Gaps = 43/525 (8%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C G P P + W + +H L G D GVY + N +G
Sbjct: 669 CEVEGWPEPELVWLVDDQ-PLRPSHDFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFG 727
Query: 93 TARSRNATLHVAV------LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
+ S+ A L V + EF+ E + +G+ V + + G P P + W NG
Sbjct: 728 SIESK-AELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVIT-GDPNPEIIWFING 785
Query: 147 QTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
+ L + DG L I+D + G C N G+ S LK+ + P
Sbjct: 786 KPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSA-SCDGRLKVRVPPAPP 844
Query: 206 T--GP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKVLD-DGSLRL 259
T P ED Q S+V F+ V G P P + + + G + G V+++ DG R+
Sbjct: 845 TFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTF--TLCGKELKNGEEGVEIVGHDGFYRI 902
Query: 260 D--NVIL-ADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
N + +GE +A+N G + LTV P+ V++G
Sbjct: 903 SIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEF 962
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A F T G P P + W + G++ + G K A +T+ D T
Sbjct: 963 AVFETTVRGNPNPEVTWFINGHK--MDQGSPGVKIEAHNHDHKLTI------DSAQYAGT 1014
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
++C A N G + +L V + + + PP ++T + + VF P+P
Sbjct: 1015 VLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPT 1074
Query: 429 IAWYFEGEALIQNHRRNVTN-DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
+ WY +GE L Q+ R + DG+ + +K++ D+G VA++ G L V
Sbjct: 1075 VTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134
Query: 486 -SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
P P R ++ G H T WS N +
Sbjct: 1135 KKPFAPEFD-LRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGR 1178
Score = 92.7 bits (220), Expect = 1e-18
Identities = 117/517 (22%), Positives = 201/517 (38%), Gaps = 69/517 (13%)
Query: 32 NCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRATHGRVHSDAGVYWCEATNS 90
N + G P P ++W+ G+ + D ++ A G + L R D G C A N
Sbjct: 5191 NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVR-EEDFGTLKCIAKNE 5249
Query: 91 YGTARS----RNATLHVAVLREEFRLEPE------SKQSAQGDTVVLECLPPRGSPEPNV 140
GT + + H R++ R P ++ GD + +EC +P V
Sbjct: 5250 NGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVD-ANPTAEV 5308
Query: 141 YWKKNGQTLLFDGDSRM-HLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
W K+G+ + + + + VDG + I ++D G Y C+A N G E+ AT ++
Sbjct: 5309 EWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQ-ATYQV 5367
Query: 199 HIKPYL-----------ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
I ++ I P ED G + C+V P V+W + +PL
Sbjct: 5368 EILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG----LPL 5423
Query: 247 GR-----VKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------- 292
++ +DG+ L +++ D G Y C A N+ G ++ S + V P
Sbjct: 5424 RADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE 5483
Query: 293 ---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P + + G+ C TG P P + W G + R +
Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ---LLRNGPRTVIETSP- 5539
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---------GKLTVTSDDDRPPPII 400
DG LT+N++ +D C A N G + + GK D+ PP
Sbjct: 5540 -DGSCSLTVNESTMSDE-GIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKF 5597
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLK 455
S+ ++ + ++ C P P + W +G LI++ R +N+ + L +K
Sbjct: 5598 ILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIK 5657
Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+ D GTY CVA++ +G + +D + +
Sbjct: 5658 NATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGV 5694
Score = 91.5 bits (217), Expect = 3e-18
Identities = 110/474 (23%), Positives = 186/474 (39%), Gaps = 49/474 (10%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
+P ++WYK + ++H G + A + D Y +N+ G S
Sbjct: 4898 APVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSS 4957
Query: 98 NATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
A V VL+ L+ + Q V L+ + G P+ + W KNGQ L D D
Sbjct: 4958 AALTVVKPNVLKIVDGLKDVDVEEPQ--PVELK-VKVEGIPKV-IKWYKNGQELKPDADG 5013
Query: 156 RM--HLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--- 208
+ G +L I ++++D G Y+ + N G S +H+K + P
Sbjct: 5014 FKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSV---VHVKSAKSSEPTSG 5070
Query: 209 -------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLR 258
+D + G +T QC + G+P P+V+W + + RV + +LR
Sbjct: 5071 ANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLR 5130
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARF 312
+ + +D G+Y A+N G+ ++ +TV + P + + G+ F
Sbjct: 5131 IRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEF 5190
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
G P+PT+ W + G P D+ + DG LTI D + D T+ C
Sbjct: 5191 NVKVRGLPKPTLQWFLNG-----IPIKFDDRITLDDMADGNYCLTIRDVREEDF-GTLKC 5244
Query: 373 SAVNYAGSSFV-------RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
A N G+ G + DD R PP ++ +P+ C P
Sbjct: 5245 IAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANP 5304
Query: 426 EPIIAWYFEGEALIQNHRRNVTN--DGTLVLK--DLDKSDSGTYTCVASSRHGK 475
+ W+ +G+ + + N DG +K ++SD G Y CVA + G+
Sbjct: 5305 TAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQ 5358
Score = 90.2 bits (214), Expect = 8e-18
Identities = 118/480 (24%), Positives = 194/480 (40%), Gaps = 35/480 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + + G + L
Sbjct: 4400 PEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEI 4456
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ ++ D Y +N G A S +A L V + E + +G VL+
Sbjct: 4457 PNAQL-DDTADYKVVVSNDAGDADS-SAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVET 4514
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAG- 187
+ E + W KNG+ + D DG N LVI DA DA Y+ + + G
Sbjct: 4515 NKKPKE--IKWYKNGKEIT-PSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGN 4571
Query: 188 TRESAIA-TLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242
T +S+ A T+K+ K P +I G ED V GS + + G P V W ++ G
Sbjct: 4572 TADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSP-KTVKWYKNGKELPGA 4630
Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP- 299
+++ +DD L + + ++ D G+Y E N G+ ++SG +TV +P L P
Sbjct: 4631 AAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-EPKITFLKPL 4689
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
++ G A F+ +P + W G I P ++ D L I
Sbjct: 4690 KDQSITEGENAEFSVETNTKPR-IVKWYKNGQE--IKP---NSRFIIEQKTDTKYQLVIK 4743
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
+ ++D+ +T N AG + +LTV I+ G +Q + + VF
Sbjct: 4744 NAVRDDA-DTYKIVLENTAGEAESSAQLTVKKAKAGLCKIV-KGLEDQVVAKGAKMVFEV 4801
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTN-DGT---LVLKDLDKSDSGTYTCVASSRHGK 475
PE + W + + + D T L++ D D+G YT + GK
Sbjct: 4802 KIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGK 4860
Score = 88.2 bits (209), Expect = 3e-17
Identities = 79/284 (27%), Positives = 116/284 (40%), Gaps = 10/284 (3%)
Query: 30 TLNCRA--GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
TL C+ G P+P ++WY G LV + I A G++ ++ HG G C A
Sbjct: 2579 TLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMK-IHGVTADMTGKIKCVA 2637
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + VA + EF +GDT+ L + G PEP V W NG+
Sbjct: 2638 YNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAV-LLGEPEPVVSWYVNGK 2696
Query: 148 TLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYL 204
L + ++H G + I+D +G+ C A N G T E+ + L P
Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVI 263
+ +V A+TG+ V + GDP P + W + N L + D S N
Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816
Query: 264 LAD--EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
D GE C+AEN G VS + + Y + S + E
Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAE 2860
Score = 86.6 bits (205), Expect = 9e-17
Identities = 98/460 (21%), Positives = 167/460 (36%), Gaps = 28/460 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P D V + G P P++ W G V + ++ G +
Sbjct: 2365 EVPKFTTNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTI 2424
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVL 127
+ AG CEATN G+ + R+ L V + + F E + +G+ ++
Sbjct: 2425 EIS-AVTPEQAGELSCEATNPVGS-KKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLM 2482
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNA 185
+ P+P + W K+G + DG ++ + G+L + + D GR A +
Sbjct: 2483 DAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESE 2542
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV--TFQCR--VGGDPLPDVLW----RR 237
G E + + + +P + +A + T +C+ + GDP P V W +
Sbjct: 2543 FGVAECSASLGVVKGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQL 2602
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
+ + + ++++ V G+ C A N G VS G L V P +
Sbjct: 2603 VCATEDTEISNANGVY--TMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEF 2660
Query: 298 SPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+ G+ + G PEP + W V G + K H+ G
Sbjct: 2661 ETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKK---LEESQNIKIHSEK---GTYT 2714
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+TI D D +VC A+N G + L V + PP SN +
Sbjct: 2715 VTIKDITC-DYSGQVVCEAINEYGKATSEATLLVLPRGE--PPDFLEWLSNVRARTGTKV 2771
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVL 454
V P+P + WY + ++ + VT+D T L
Sbjct: 2772 VHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTL 2811
Score = 86.2 bits (204), Expect = 1e-16
Identities = 80/296 (27%), Positives = 130/296 (43%), Gaps = 31/296 (10%)
Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAG-GLFFLRATHG 74
+PL+V + L G+P P + W+K + + ++H G G L
Sbjct: 3489 RPLEVR--EQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQA 3546
Query: 75 RVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R D GVY C+ATN G A++ N + + F + + QG L +
Sbjct: 3547 R-GEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAEL-VVRVE 3604
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGN----LVIQDARQTDAGRYQCIARNAAG 187
G PEP V W K+G + D H+++ G N LVI+D D G+Y C A N AG
Sbjct: 3605 GKPEPEVKWFKDGVPIAIDNQ---HVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAG 3661
Query: 188 TRESAIATLKI-----------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
++ + LKI +KP I ++ A G +V +C+V + P + +
Sbjct: 3662 -KDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFF 3720
Query: 237 RSAGGGNMPLG-RVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ + +++VL+DG+++L N D G Y CEA N G + + L +
Sbjct: 3721 KNDQPVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776
Score = 81.0 bits (191), Expect = 5e-15
Identities = 123/534 (23%), Positives = 198/534 (37%), Gaps = 37/534 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP ++ + V + A C+ G+ P ++W+K G + D
Sbjct: 4017 APGFFKELSAIQVKETETAKFECKVSGT-KPDVKWFKDGTPLKEDKRVHFESTDDGTQRL 4075
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D G Y E +N G A S+ V + + QG ++L +
Sbjct: 4076 VIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLS-V 4134
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCI-ARNAAG 187
G P+ V W K +T+ +++ V L I+ A +D G Y+ + + ++
Sbjct: 4135 EVEGKPK-TVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFS 4193
Query: 188 TRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
SA T+ KI + P G D G+ + + + G P DV W ++ G
Sbjct: 4194 VESSATVTVTKAAEKISL-PSFKKGLADQSVPKGTPLVLEVEIEGKP-KDVKWYKN--GD 4249
Query: 243 NMPLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
+ G+V+ L +G RL + D GEYS A N G + + + V P I
Sbjct: 4250 EIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLV 4309
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
V+ G A F G P + W G I ++D DG L I +
Sbjct: 4310 PTTVKQGETATFNVKVKG-PVKGVKWYKNGKE--IPDAKTKDN------GDGSYSLEIPN 4360
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDD--DRPPPIITNGPSNQTLPIKSMAVF 417
D+ + V + N AG + LTV +DD D+ P I +G T+ A F
Sbjct: 4361 AQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATF 4419
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475
+ P + WY G+ I N + DG +L + + D+ Y V S+ G
Sbjct: 4420 N-VKVKGPVKQVKWYKNGKE-IPNAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGD 4477
Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
S AL V P I + + + +P + + W +N K
Sbjct: 4478 ADSSAALTVKL---PGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGK 4528
Score = 80.6 bits (190), Expect = 6e-15
Identities = 102/403 (25%), Positives = 167/403 (41%), Gaps = 33/403 (8%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA-GGL 66
G+AP + D + + ++ + P P I W K GV + SD H I+ G
Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQG 122
L ++ D G +A + +G A +A+L V + + F+ + +G
Sbjct: 2520 LKLSILQTKLE-DKGRITIKAESEFGVAEC-SASLGVVKGRPMAKPAFQSDIAPINLTEG 2577
Query: 123 DTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQC 180
DT LEC L G P P V W Q + D+ + +G + I G+ +C
Sbjct: 2578 DT--LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKC 2635
Query: 181 IARNAAGTRESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+A N AG S LK+ + P + T D + G ++ + + G+P P V W
Sbjct: 2636 VAYNKAG-EVSTEGPLKV-VAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693
Query: 238 SAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---D 291
+ G +K+ + ++ + ++ G+ CEA N G ++ L V +
Sbjct: 2694 N-GKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGE 2752
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP ++V +G TG P+P++ W + N+ I+ + D Y T V D
Sbjct: 2753 PPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYIN-NKEIL----NSDLY--TIVTD 2805
Query: 352 GVT-VLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSD 392
T LTIN + + I+C A N AG S +T TSD
Sbjct: 2806 DKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTANMITYTSD 2848
Score = 75.8 bits (178), Expect = 2e-13
Identities = 99/334 (29%), Positives = 140/334 (41%), Gaps = 50/334 (14%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSI 60
D + G+AP PL + A+ T C G+P P+I+W K G+ + SD +
Sbjct: 5916 DSSIREGKAPGFTT-PLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKME 5974
Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-------EEFRLE 113
A G L + S+ G + C ATN +GTA S A L + R E E
Sbjct: 5975 AAADGTQRLILSDVTFLSE-GYFRCVATNEHGTA-STKAELVIEGDRTIGSRPLPEVNGE 6032
Query: 114 PES----------KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--- 160
PE S VV + G P P V W K+GQ ++ DG ++
Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092
Query: 161 DGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---------PE 209
+ G +LVI +A D G Y A N G+ ++ +L I I+P I P
Sbjct: 6093 ERGIHHLVIVNASPDDEGEYSLEATNKLGSAKTE-GSLNI-IRPRHIADADERGGMPFPP 6150
Query: 210 DVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG----SLR 258
V Q + F C V G P P+V W + G +P GR+K+ G +L
Sbjct: 6151 GFVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHN-GKKIVPGGRIKIQSCGGGSHALI 6209
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ + L D GEY A+NS G+ S+S L V P
Sbjct: 6210 ILDTTLEDAGEYVATAKNSHGSASSSAVLDVTVP 6243
Score = 75.4 bits (177), Expect = 2e-13
Identities = 74/289 (25%), Positives = 114/289 (39%), Gaps = 23/289 (7%)
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DG--SLRLDNVILADEGEYSCE 273
SS +V G PLPD+ W + + D DG ++ +D V + D G Y+C
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 274 AENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
A N G S S + V PP+ + G+V F C G PEP + W
Sbjct: 623 ATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWL 682
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
V+ R + +DG T L I D +D+ N GS + +
Sbjct: 683 VDDQPL-------RPSHDFRLQYDGQTAKLEIRDAQPDDT-GVYTVKIQNEFGSIESKAE 734
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHR- 443
L V +D D+ + + + ++ T P P I W+ G+ L ++ +
Sbjct: 735 LFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKV 794
Query: 444 RNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+ ++ DG L +KD+ + G TC S+R G G L V P P
Sbjct: 795 KFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP 843
Score = 74.5 bits (175), Expect = 4e-13
Identities = 119/491 (24%), Positives = 192/491 (39%), Gaps = 40/491 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFL 69
P II+ D V+ P L GSP ++WYK G + ++I ++
Sbjct: 4588 PKIIKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV 4646
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLE 128
V D G Y E N G+A N++ + V + L+P QS +G+ E
Sbjct: 4647 LEIPSSVVEDTGDYKVEVANEAGSA---NSSGKITVEPKITFLKPLKDQSITEGENA--E 4701
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARN 184
+ V W KNGQ + +SR + + LVI++A + DA Y+ + N
Sbjct: 4702 FSVETNTKPRIVKWYKNGQEI--KPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759
Query: 185 AAGTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
AG ES+ K L + G ED V G+ + F+ ++ G+P DV W R A
Sbjct: 4760 TAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEP-EDVRWLRDANV 4818
Query: 242 GNMPLGRV-KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
+ + + +DD + RL + L D GEY+ E N G + V + P I
Sbjct: 4819 ISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRG 4878
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
++ + G+ F + P + W N I P A + L I
Sbjct: 4879 LENIEIPEGDDDVFKVEVSA-PVRQVKW--YKNDQEIKP---NSHLEAKKIGPKKYELAI 4932
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N +D + V + N AG LTV + I +G + +
Sbjct: 4933 NRAQLDDGADYKVVLS-NAAGDCDSSAALTVVKPNVLK---IVDGLKDVDVEEPQPVELK 4988
Query: 419 CTAICTPEPIIAWYFEGEAL------IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
P+ +I WY G+ L + + + + +L + KSD G Y V +
Sbjct: 4989 VKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGND 5047
Query: 473 HGKYVWSGALL 483
G+ V+SG+++
Sbjct: 5048 KGE-VYSGSVV 5057
Score = 72.5 bits (170), Expect = 2e-12
Identities = 87/393 (22%), Positives = 159/393 (40%), Gaps = 30/393 (7%)
Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
V+ +F + + ++ +G + V EC+ P + W K+G+ + R+ G
Sbjct: 2884 VMAPKFITKIKDTKAKKGHSAVFECVVP-DTKGVCCKWLKDGKEIELIARIRVQTRTGPE 2942
Query: 165 ------LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIK------PYLITGPED 210
LV+ + DAG+Y CI N AG T E+ + ++ K P I +D
Sbjct: 2943 GHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQD 3002
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
+T V +C+V G+P P V W V+ ++ + + + L+ +G+
Sbjct: 3003 KTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTITSSELSHQGK 3062
Query: 270 YSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
Y+C AEN+ G +LTV + P + + G +C+ G P+P + +
Sbjct: 3063 YTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYS 3122
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVT--VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
T + ++ A T + I+ K D + A N G++ K
Sbjct: 3123 FSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDI-VSYKAIATNSIGTATSTSK 3181
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NH-- 442
+T + P+ G ++ K + P + W+ + + + + NH
Sbjct: 3182 ITTKVE----APVFEQGLKKTSVKEKEEIKME-VKVGGSAPDVEWFKDDKPVSEDGNHEM 3236
Query: 443 RRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
++N T TLV+K +D+G YT AS+ G
Sbjct: 3237 KKNPETGVFTLVVKQAATTDAGKYTAKASNPAG 3269
Score = 72.5 bits (170), Expect = 2e-12
Identities = 119/493 (24%), Positives = 193/493 (39%), Gaps = 42/493 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + G + L
Sbjct: 4302 PEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD--NGDGSYSLEI 4358
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSA------QGDT 124
+ +V DA Y +N G A S +A L V + + + +++PE QG+T
Sbjct: 4359 PNAQVE-DAADYKVVVSNDAGDADS-SAALTVKLADDGKDKVKPEIVSGLIPTTVKQGET 4416
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ +G P V W KNG+ + + ++ + +L I +A+ D Y+ + N
Sbjct: 4417 ATFN-VKVKG-PVKQVKWYKNGKEIP-NAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSN 4473
Query: 185 AAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
AG +S+ A T+K+ ++ G ED G Q P ++ W ++ G
Sbjct: 4474 DAGDADSSAALTVKLP-GIAIVKGLEDAEVPKGKKAVLQVETNKKP-KEIKWYKN-GKEI 4530
Query: 244 MPLGRVKVLDDGSLRLDNVILA----DEGEYSCEAENSVG-AVSASGYLTVYDP---PSI 295
P + + DG + VI D EY + G +S LTV P P I
Sbjct: 4531 TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKI 4590
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
V G+ + +G P+ T+ W G PG + + D V
Sbjct: 4591 IKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKE---LPGAAAKTIKIQKIDDNKYV 4646
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L I + D+ + V N AGS+ GK+TV P +Q++ A
Sbjct: 4647 LEIPSSVVEDTGDYKV-EVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGENA 4700
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
F P I+ WY G+ + N R + LV+K+ + D+ TY V +
Sbjct: 4701 EFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759
Query: 472 RHGKYVWSGALLV 484
G+ S L V
Sbjct: 4760 TAGEAESSAQLTV 4772
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 15/207 (7%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG---QTLLFDGDSRMHLVDGGN--LVIQD 169
E + A+ DT+ + L G P+P++ WK G T +++ G L I
Sbjct: 6417 EKRYCAENDTLTI-VLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITG 6475
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
+ + G+YQC A+N G + I + + +P I + + + RV G+P
Sbjct: 6476 FSKENVGQYQCFAKNDYGDAQQNIM-VDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P++ W + + R+K + DG SL +++ + D G YSC A N G + S
Sbjct: 6535 FPELKWMKE-WRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 6593
Query: 286 YLTVY---DPPSINLSPNSVNVESGNV 309
+TV D + L V +ES V
Sbjct: 6594 TVTVEAEGDYNDVELPRRRVTIESRRV 6620
Score = 64.1 bits (149), Expect = 6e-10
Identities = 94/423 (22%), Positives = 157/423 (37%), Gaps = 33/423 (7%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
S AP ++ D TV + A G+P+P + W+ G + + + A
Sbjct: 942 SRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHD 1001
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-------SKQSA 120
+ AG C A N+ G ++ + VL E + +P K
Sbjct: 1002 HKLTIDSAQY--AGTVLCRAENAVGRFETK---ARLVVLAPEKQKKPPKFVEILVDKTET 1056
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179
+TVV E + G P+P V W G+ L + DG + I++ + DAG +
Sbjct: 1057 VDNTVVFE-VRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115
Query: 180 CIARNAAGTRESAIATLKIHIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
+A N+ G+ E+ A L + KP+ P + + GS F G PLP W
Sbjct: 1116 AVATNSEGSDETK-AKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWS 1174
Query: 237 RSA-----GGGNMPLGRVKVLDDGS--LRLDNVILADEGEY---SCEAENSVGAVSASGY 286
+ G + R + DG+ L +D E + S AEN++GA
Sbjct: 1175 VNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQ 1234
Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTC--TATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
LT+ +P ++ ++ S V + PE T ++E + T +
Sbjct: 1235 LTI-EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEATTTITMETSLTST-KTTTMSTT 1292
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
T+ GVTV T +++ + I + S K+ V S D + P
Sbjct: 1293 EVTSTVGGVTVET-KESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVREGTP 1351
Query: 405 SNQ 407
+
Sbjct: 1352 KRR 1354
Score = 61.7 bits (143), Expect = 3e-09
Identities = 66/257 (25%), Positives = 93/257 (36%), Gaps = 16/257 (6%)
Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
+VG ++S T P S V A C G P P + W+ EG
Sbjct: 3801 TVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEV--- 3857
Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD--- 393
MS + A DG LT ++ + D+ C A N GS++ G + VT +
Sbjct: 3858 -EMSA-RVRAEHKDDGTLTLTFDNVTQADA-GEYRCEAENEYGSAWTEGPIIVTLEGAPK 3914
Query: 394 -DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DG 450
D P + + AV P+P + WY GE L + R + N DG
Sbjct: 3915 IDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDG 3974
Query: 451 T--LVLKDLDKSDSGTYTCVASSRHGKYVWSG-ALLVDSPINPNIHFFRAADVSSLPGPP 507
T L + + D Y C AS+ G VWS L V P FF+ +
Sbjct: 3975 TQRLTVTNAKLDDMDEYRCEASNEFGD-VWSDVTLTVKEPAQVAPGFFKELSAIQVKETE 4033
Query: 508 TKPITHNVTDTSVTLSW 524
T V+ T + W
Sbjct: 4034 TAKFECKVSGTKPDVKW 4050
Score = 60.5 bits (140), Expect = 7e-09
Identities = 89/376 (23%), Positives = 149/376 (39%), Gaps = 27/376 (7%)
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
D +G +A NAAG+ E+ LK+ P PE VT V D
Sbjct: 1944 DTTMFGSGTVSVVASNAAGSVETK-TELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMD 2002
Query: 229 --PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVGAVSA 283
L L++ G + G+ V ++I+ D G+ + EA N VG+ +
Sbjct: 2003 VIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSES 2062
Query: 284 SGYLTVYDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
S LTV P P + P SV ++ A F T +G P PT+ W++ N I+
Sbjct: 2063 SAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTI--NEKIV----E 2116
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP--PP 398
+ T + V L I++ K + T+ +A N AG + L V + P
Sbjct: 2117 ESRTITTIKTEDVYTLKISNA-KIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGT--LVL 454
+T+ +++ P++ +P ++W G+ L ++ V + DGT + +
Sbjct: 2176 QLTDKVADEGEPLRWNLELDGP---SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTI 2232
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514
+ SGT T A + G+ S + V+ N F +A + +
Sbjct: 2233 AEAKPEMSGTLTAKAKNAAGECETSAKVTVNGG-NKKPEFVQAPQNHETTLEESVKFSAI 2291
Query: 515 VTDTSV-TLSWSQNNK 529
VT + ++W NNK
Sbjct: 2292 VTGKPMPNVTWYLNNK 2307
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 12/171 (7%)
Query: 24 ARHQPATLNCRAGGSPSPAIRW-YKG-GVLVVSDTHR-SILPAGGLFFLRATHGRVHSDA 80
A + T+ G P P I+W ++G + S T + + GG A G +
Sbjct: 6422 AENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENV 6481
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N YG A+ +N + +A R F ++P ++ + + G P P +
Sbjct: 6482 GQYQCFAKNDYGDAQ-QNIMVDLAT-RPNF-IQPLVNKTFSSAQPMRMDVRVDGEPFPEL 6538
Query: 141 YWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG 187
W K + ++ SR+ V G +L+I D D+G Y C+A N AG
Sbjct: 6539 KWMKEWRPIV--ESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAG 6587
Score = 39.9 bits (89), Expect = 0.011
Identities = 21/83 (25%), Positives = 36/83 (43%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ ++ T + QP ++ R G P P ++W K +V + + G
Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566
Query: 72 THGRVHSDAGVYWCEATNSYGTA 94
+ + D+G+Y C A N G A
Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQA 6589
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P P + W E ++++ R DG +L++ D DSG Y+CVA + G+ S
Sbjct: 6534 PFPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 6593
Query: 481 ALLVDS 486
+ V++
Sbjct: 6594 TVTVEA 6599
>AF003131-3|AAV34801.1| 7122|Caenorhabditis elegans Uncoordinated
protein 89, isoform g protein.
Length = 7122
Score = 146 bits (354), Expect = 8e-35
Identities = 178/689 (25%), Positives = 281/689 (40%), Gaps = 110/689 (15%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAG 64
VT+ + P + DV QP L C+ SP P + WYK G +V SD + L
Sbjct: 5695 VTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPD 5754
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLREEFR--- 111
G+ L V+ D G+Y ATN GTA+ R++ + R+ F
Sbjct: 5755 GVATLLIP-SCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANK 5813
Query: 112 ----LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-- 164
+EP E+ + + + L C G P+P + W K+G+ + G R+ L++ +
Sbjct: 5814 APKLMEPLENIRIPEKQSFRLRC-KFSGDPKPTIKWFKDGERVFPYG--RLQLIESPDGV 5870
Query: 165 --LVIQDARQTDAGRYQCIARNAAGTRESA--IATLKIHIKPYLI------------TGP 208
LV+ A + DAG Y+C+A N G+ ++ + ++ KP I T P
Sbjct: 5871 CELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTP 5930
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL--DNVI 263
+ A+ G SVTF+C G+P P + W + G ++K+ DG+ RL +V
Sbjct: 5931 LTIRRAKPGDSVTFECLPFGNPFPSIKWLKD-GLELFSDEKIKMEAAADGTQRLILSDVT 5989
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDP--------PSINLSPN-----------SVNV 304
EG + C A N G S L + P +N P ++++
Sbjct: 5990 FLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMSI 6049
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
GNV ATG P PT+ W +G + I+ G + T G+ L I + +
Sbjct: 6050 HEGNVVEMIVCATGIPTPTVKWYKDG-QEIVGDGPDGKRVIFTDE-RGIHHLVIVNASPD 6107
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLT------VTSDDDRP----PPIITNGPSNQTLPIKSM 414
D A N GS+ G L + D+R PP N+ +
Sbjct: 6108 D-EGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMP 6166
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVAS 470
+F C + P P + W+ G+ ++ R + + G L++ D D+G Y A
Sbjct: 6167 TIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATAK 6226
Query: 471 SRHGKYVWSGALLVDSPINPNIHF---------------FRAADVSSLPGPPTK-PITHN 514
+ HG S L V P +I F F+ + +SLP PP + P
Sbjct: 6227 NSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKKLNTASLPTPPDRGPFIKE 6286
Query: 515 VTDTSVTLSWSQNNKIGSS-SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
VT +TLSW + + Y +E+ RE + W ++ + +
Sbjct: 6287 VTGHYLTLSWIPTKRAPPRYPQVTYVIEI--REL--------PEKQWSLLEYNIPEPVCK 6336
Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVS 602
V++L G +Y F VR EN +G+S PSP S
Sbjct: 6337 VRNLELGKSYQFRVRAENIYGISDPSPAS 6365
Score = 140 bits (339), Expect = 5e-33
Identities = 139/499 (27%), Positives = 208/499 (41%), Gaps = 62/499 (12%)
Query: 28 PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-PAGGLFFLRATHGRVHSDAGVYWCE 86
P + C +P+ + W+K G + H I G ++ SD GVY C
Sbjct: 5293 PMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFE-ESDIGVYMCV 5351
Query: 87 ATNSYGTARSRNATLHVAVL-------REEF--RLEP--ESKQSAQGDTVVLECLPPRGS 135
A N G A ++ AT V +L R E+ ++ P E K G + L C
Sbjct: 5352 AVNELGQAETQ-ATYQVEILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSC-KVDAI 5409
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGT-RESA 192
P +V W K+G L D + + + G L I D+ + D G Y+C+A NA GT S
Sbjct: 5410 PRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSC 5469
Query: 193 IATLKI---HIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGN 243
+K+ +K P+ G D+ A G S T +C V GDP P++ W R+ N
Sbjct: 5470 SVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRN 5529
Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY----------- 290
P ++ DG SL ++ ++DEG Y CEAEN+ G V
Sbjct: 5530 GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKM 5589
Query: 291 ---DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
PP L + ++V GNV C TG P P++ WS +G I SR ++ +
Sbjct: 5590 DEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLI---EDSRFEW-SN 5645
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSN 406
GV L I + +D T C A N GS+ K V DD ++T + P
Sbjct: 5646 EASKGVYQLRIKNATVHD-EGTYRCVATNENGSATT--KSFVRMDDGLGSGVVTASQPPR 5702
Query: 407 QTLPIKSMAV-------FPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDG--TLVLK 455
TL + + C +P P + WY +G + + R + + DG TL++
Sbjct: 5703 FTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIP 5762
Query: 456 DLDKSDSGTYTCVASSRHG 474
D G Y +A++ G
Sbjct: 5763 SCVYDDDGIYRVIATNPSG 5781
Score = 139 bits (336), Expect = 1e-32
Identities = 142/521 (27%), Positives = 221/521 (42%), Gaps = 71/521 (13%)
Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I PL D TV QP L+C+ P ++ WYK G+ + +D+ SI A +
Sbjct: 5385 INPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIN 5444
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---------QSAQGDT 124
D G Y C ATN++GT + + +++V V ++E + E E + +GD+
Sbjct: 5445 DSTEEDIGAYRCVATNAHGTINT-SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDS 5503
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGG-NLVIQDARQTDAGRYQCI 181
L+C G P P + W +NGQ LL +G + DG +L + ++ +D G Y+C
Sbjct: 5504 FTLKC-AVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561
Query: 182 ARNAAG-TRESAIATLKIHI----KPYLITGP--------EDVVAQTGSSVTFQCRVGGD 228
A NA G + A A +++ + KP + G D+ G+ + +C+V G
Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGL 5621
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVS- 282
P P V W + GG + R + ++ S LR+ N + DEG Y C A N G+ +
Sbjct: 5622 PNPSVKWSKD-GGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATT 5680
Query: 283 ----------ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
SG +T PP L V G + C P P M W +G
Sbjct: 5681 KSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG-- 5738
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--- 389
I+ P D+ + DGV L I +D V A N +G++ +G TV
Sbjct: 5739 AIVTPS---DRIQISLSPDGVATLLIPSCVYDDDGIYRVI-ATNPSGTAQDKGTATVKKL 5794
Query: 390 --------TSD----DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
++D D P + N +P K C P+P I W+ +GE
Sbjct: 5795 PRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGER 5854
Query: 438 LIQNHRRNV--TNDGT--LVLKDLDKSDSGTYTCVASSRHG 474
+ R + + DG LV+ + D+G Y CVA + +G
Sbjct: 5855 VFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYG 5895
Score = 136 bits (328), Expect = 1e-31
Identities = 127/499 (25%), Positives = 210/499 (42%), Gaps = 32/499 (6%)
Query: 7 TSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PA 63
T EAP + EQ L T V + + + GGS +P + W+K V D + + P
Sbjct: 3184 TKVEAP-VFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDDKPVSEDGNHEMKKNPE 3241
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQG 122
G+F L +DAG Y +A+N GTA S A + ++ + F E + +
Sbjct: 3242 TGVFTLVVKQAAT-TDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKIN 3300
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQ 179
+T L + +G P+P+V W K+GQ + D + V+G ++ I+DAR D+G+Y
Sbjct: 3301 ETATLS-VTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYA 3359
Query: 180 CIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
C A N AG E+ A +K + P + + + S T +V G P P V W +
Sbjct: 3360 CRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFK 3419
Query: 238 SAGGGNMP----LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYD- 291
++ + + + SL +++ D G YSC A N G A++ + + + D
Sbjct: 3420 DDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS 3479
Query: 292 -PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
PP + V T G P P + W + ++ I + A
Sbjct: 3480 IPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEW-FKDDKPI---NIDNSHIFAKDEG 3535
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G LTI + + C A N AG + + V + + P + G +
Sbjct: 3536 SGHHTLTIKQA-RGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP--LFVQGLKPYEVE 3592
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTY 465
A PEP + W+ +G + +++ + G TLV+KD + +D G Y
Sbjct: 3593 QGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKY 3652
Query: 466 TCVASSRHGKYVWSGALLV 484
TC A+++ GK G L +
Sbjct: 3653 TCQATNKAGKDETVGELKI 3671
Score = 135 bits (327), Expect = 2e-31
Identities = 129/483 (26%), Positives = 199/483 (41%), Gaps = 34/483 (7%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + + G P P I WYK V + D + FF +D G Y C AT
Sbjct: 565 AKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMAT 624
Query: 89 NSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
N YG A S +A V + +E F + K+ +GD + EC G PEP + W
Sbjct: 625 NEYGQA-STSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFEC-EVEGWPEPELVWL 682
Query: 144 KNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL----- 196
+ Q L D R+ DG L I+DA+ D G Y +N G+ ES
Sbjct: 683 VDDQPLRPSHDFRLQ-YDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADP 741
Query: 197 -KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDD 254
K H+ P E V G V F+ + GDP P+++W + G +VK + +D
Sbjct: 742 DKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFIN-GKPLSESEKVKFISED 800
Query: 255 G--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNV 309
G L + +V +G +C+ N +G+ S G L V PP+ N V+ +
Sbjct: 801 GICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKST 860
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
F +G PEPT+ +++ G + ++ DG ++I +T +
Sbjct: 861 VVFEVDVSGWPEPTLTFTLCGKEL-----KNGEEGVEIVGHDGFYRISIPNTSMDKHDGE 915
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDD--RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
IV A N G++ R +LTV +++ R P +QT+ AVF T P P
Sbjct: 916 IVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNP 975
Query: 428 IIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
+ W+ G + Q + N + D +GT C A + G++ L+V
Sbjct: 976 EVTWFINGHKMDQGSPGVKIEAHNHDHKLTID-SAQYAGTVLCRAENAVGRFETKARLVV 1034
Query: 485 DSP 487
+P
Sbjct: 1035 LAP 1037
Score = 126 bits (303), Expect = 1e-28
Identities = 139/544 (25%), Positives = 222/544 (40%), Gaps = 78/544 (14%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GE P+ + +D+ R TL C G P P I+WY+ G L+ + I +
Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC 5543
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREE-----------FRLEPE 115
+ SD G+Y CEA N++G A+++ AT HV A+ + E F LE
Sbjct: 5544 SLTVNESTMSDEGIYRCEAENAHGKAKTQ-ATAHVQMALGKTEKPKMDEGKPPKFILELS 5602
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-----LVIQDA 170
+ G+ + LEC G P P+V W K+G L+ DSR + + L I++A
Sbjct: 5603 DMSVSLGNVIDLEC-KVTGLPNPSVKWSKDGGPLI--EDSRFEWSNEASKGVYQLRIKNA 5659
Query: 171 RQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPE---------DVVAQTGSSVT 220
D G Y+C+A N G+ + + + + ++T + DV G +
Sbjct: 5660 TVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLK 5719
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDG--SLRLDNVILADEGEYSCEAEN 276
+C+V PLP+++W + G P R+++ DG +L + + + D+G Y A N
Sbjct: 5720 LECKVDASPLPEMVWYKD-GAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATN 5778
Query: 277 SVGAVSASGYLTVYDPP--------------SINLSP------NSVNVESGNVARFTCTA 316
G G TV P N +P ++ + R C
Sbjct: 5779 PSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKF 5838
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
+G P+PT+ W +G R +FP + DGV L ++ + D+ C A N
Sbjct: 5839 SGDPKPTIKWFKDGER--VFP---YGRLQLIESPDGVCELVVDSATRQDA-GGYRCVAEN 5892
Query: 377 YAGSSFVRGKLTVTSDDDRPPPI---ITNGPS-NQTLPIK-------SMAVFPCTAICTP 425
GS+ + V D +P I I G + T P+ F C P
Sbjct: 5893 TYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNP 5952
Query: 426 EPIIAWYFEGEALIQNH--RRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P I W +G L + + DGT L+L D+ G + CVA++ HG
Sbjct: 5953 FPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 6012
Query: 482 LLVD 485
L+++
Sbjct: 6013 LVIE 6016
Score = 124 bits (298), Expect = 5e-28
Identities = 126/498 (25%), Positives = 203/498 (40%), Gaps = 46/498 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLF 67
E P + + + V ++ ATL+ G P P++ W K G V +D+ I + G +
Sbjct: 3284 EKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSY 3343
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEF--RLEPESKQSAQGDT 124
+ R+ D+G Y C ATN G A++ N + ++ EF +L P + + T
Sbjct: 3344 SITIKDARLE-DSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTT 3402
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCI 181
+ ++ + G+PEP+V W K+ + D + V +L I DARQ D G Y C
Sbjct: 3403 LSVKVV---GTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCR 3459
Query: 182 ARNAAG--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
ARN AG + ++ I P + + ++ + V G P+P+V W +
Sbjct: 3460 ARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDD 3519
Query: 240 GGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
N+ + D+GS L + D G Y+C+A N G + + V +
Sbjct: 3520 KPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEA 3579
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV--F 350
P VE G A G+PEP + W +G I D H
Sbjct: 3580 PLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAI------DNQHVIEKKGE 3633
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--------TSDDDRPPPIITN 402
+G L I DT+ D C A N AG G+L + T+++ +P +
Sbjct: 3634 NGSHTLVIKDTNNADF-GKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKP---LFI 3689
Query: 403 GPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR-NVTNDGT--LVLKDL 457
P +T ++ V C P I ++ + + I H + V DG L +++
Sbjct: 3690 EPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNA 3749
Query: 458 DKSDSGTYTCVASSRHGK 475
K D G Y C A + GK
Sbjct: 3750 KKEDVGAYRCEAVNVAGK 3767
Score = 112 bits (270), Expect = 1e-24
Identities = 127/493 (25%), Positives = 204/493 (41%), Gaps = 39/493 (7%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGG 65
T AP +E TV Q A L C+ G P P I+W K G V +S R+ G
Sbjct: 3812 TGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDG 3871
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---- 121
L +DAG Y CEA N YG+A + + L +++ E+ Q
Sbjct: 3872 TLTL-TFDNVTQADAGEYRCEAENEYGSAWTEGPI--IVTLEGAPKIDGEAPDFLQPVKP 3928
Query: 122 -----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTD 174
G+T VLE G P+P+V W KNG+ L ++ +D G L + +A+ D
Sbjct: 3929 AVVTVGETAVLEG-KISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDD 3987
Query: 175 AGRYQCIARNAAGTRESAIA-TLK--IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
Y+C A N G S + T+K + P + + + F+C+V G P
Sbjct: 3988 MDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECKVSGTK-P 4046
Query: 232 DVLWRRSAGGGNMPLGRV--KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYL 287
DV W + G RV + DDG+ RL ++ D+G Y E N G ++ L
Sbjct: 4047 DVKWFKD-GTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPL 4105
Query: 288 TVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
TV ++ + VNV G + G+P+ T+ W +G T+ S
Sbjct: 4106 TVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPK-TVKW-YKGTETV----TSSQTTK 4159
Query: 346 ATAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDR-PPPIITNG 403
V + L I + +D+ +V S +++ S +TVT ++ P G
Sbjct: 4160 IVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVES--SATVTVTKAAEKISLPSFKKG 4217
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDS 462
++Q++P + V P+ + WY G+ + ++ N L + D + D
Sbjct: 4218 LADQSVPKGTPLVLEVEIEGKPKD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDV 4276
Query: 463 GTYTCVASSRHGK 475
G Y+ A++ G+
Sbjct: 4277 GEYSVTAANEAGE 4289
Score = 107 bits (257), Expect = 5e-23
Identities = 120/492 (24%), Positives = 196/492 (39%), Gaps = 35/492 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P +++ P VT+ + A G P+P ++W +V + + ++ L+
Sbjct: 2075 PIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKI 2134
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLEC 129
++ ++ G A NS G S+ A L V V +F+ + K + +G+ +
Sbjct: 2135 SNAKI-EQTGTVKVTAQNSAG-QDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNL 2192
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNA 185
SP V W NGQ L + +VD G ++ I +A+ +G A+NA
Sbjct: 2193 ELDGPSPGTEVSWLLNGQPL--TKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNA 2250
Query: 186 AGTRE-SAIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
AG E SA T+ + KP + P++ SV F V G P+P+V W ++
Sbjct: 2251 AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLI 2310
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPSIN 296
+ + V S+R+ ++ G EAEN G V A+ L V + P
Sbjct: 2311 QSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFT 2370
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTV 355
+ + V+ G +FT G PEP++ W++ G P ++ DK DG
Sbjct: 2371 TNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDK-------DGEHT 2423
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I+ + + C A N GS +L V D P ++ + +
Sbjct: 2424 IEISAVTP-EQAGELSCEATNPVGSKKRDVQLAVKKVGD--APTFAKNLEDRLITEGELT 2480
Query: 416 VFPCTA-ICTPEPIIAWYFEG-EALIQNHRRNV-TNDGTLVLKDLDK--SDSGTYTCVAS 470
+ I P+P I W +G E H + V DG+L L L D G T A
Sbjct: 2481 LMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAE 2540
Query: 471 SRHGKYVWSGAL 482
S G S +L
Sbjct: 2541 SEFGVAECSASL 2552
Score = 106 bits (255), Expect = 8e-23
Identities = 116/490 (23%), Positives = 195/490 (39%), Gaps = 39/490 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP I D T + L C+ G P P + W + ++ ++ G+ +
Sbjct: 2992 KAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQES-ITVESVEGVERV 3050
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
T + S G Y C A N+ GT+++ A L V F E ++K+ + G+ +VL C
Sbjct: 3051 TITSSEL-SHQGKYTCIAENTEGTSKT-EAFLTVQGEAPVFTKELQNKELSIGEKLVLSC 3108
Query: 130 LPPRGSPEPNVYWKKNGQTLLFD----GDSRMHLV-DGGN----LVIQDARQTDAGRYQC 180
+GSP+P+V + +T + SR+ + D N +VI + D Y+
Sbjct: 3109 -SVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKA 3167
Query: 181 IARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS- 238
IA N+ GT S + T K+ P G + + + + +VGG PDV W +
Sbjct: 3168 IATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDD 3225
Query: 239 ---AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
+ GN + + +L + D G+Y+ +A N G +S V +
Sbjct: 3226 KPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEK 3285
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD- 351
P+ + V+ A + T G P+P++ W +G + D H A +
Sbjct: 3286 PTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQ------PVQTDSSHVIAKVEG 3339
Query: 352 -GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G +TI D DS C A N AG + V + PP S +
Sbjct: 3340 SGSYSITIKDARLEDS-GKYACRATNPAGEAKTEANFAVVK--NLVPPEFVEKLSPLEVK 3396
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEAL-IQN----HRRNVTNDGTLVLKDLDKSDSGTY 465
K + TPEP + W+ + + I N ++ +L + D + D G Y
Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIY 3456
Query: 466 TCVASSRHGK 475
+C A + G+
Sbjct: 3457 SCRARNEAGE 3466
Score = 104 bits (249), Expect = 4e-22
Identities = 126/505 (24%), Positives = 191/505 (37%), Gaps = 36/505 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GEAP ++ + ++ + L+C GSP P + +Y +T + +
Sbjct: 3084 GEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEH 3143
Query: 69 LRA-THGRV------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
+ TH R+ D Y ATNS GTA S T + E E K+++
Sbjct: 3144 DQTNTHWRMVISQITKEDIVSYKAIATNSIGTATS---TSKITTKVEAPVFEQGLKKTSV 3200
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGG--NLVIQDARQTDAGRY 178
+ ++ G P+V W K+ + + DG+ M + G LV++ A TDAG+Y
Sbjct: 3201 KEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKY 3260
Query: 179 QCIARNAAGTRES---AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
A N AGT ES A T + KP + + + T V G P P V W
Sbjct: 3261 TAKASNPAGTAESSAEAEVTQSLE-KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEW 3319
Query: 236 RRSAGGGNMPLGRV--KVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
+ V KV G S+ + + L D G+Y+C A N G V
Sbjct: 3320 LKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVK 3379
Query: 292 ---PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
PP + + V+ + G PEP++ W + I K A
Sbjct: 3380 NLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVG 3439
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
F LTIND + D C A N AG + + D PP T
Sbjct: 3440 SFS----LTINDARQGDV-GIYSCRARNEAGEALTTANFGIIRDS--IPPEFTQKLRPLE 3492
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG----TLVLKDLDKSDSG 463
+ + T I TP P + W+ + + + I N ++G TL +K D G
Sbjct: 3493 VREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVG 3552
Query: 464 TYTCVASSRHGKYVWSGALLVDSPI 488
YTC A++ G+ + + V I
Sbjct: 3553 VYTCKATNEAGEAKTTANMAVQEEI 3577
Score = 102 bits (245), Expect = 1e-21
Identities = 117/404 (28%), Positives = 165/404 (40%), Gaps = 33/404 (8%)
Query: 11 APYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
AP +PL D TV G P P + + G L + I+ G +
Sbjct: 842 APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYR 901
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP------ESKQSAQG 122
+ + + G +A N +GTA SR A L V EE R P E + G
Sbjct: 902 ISIPNTSMDKHDGEIVAKAQNEHGTAESR-ARLTVEQEEEESRSAPTFLKDIEDQTVKTG 960
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRY 178
+ V E RG+P P V W NG + D S ++ N L I A+ AG
Sbjct: 961 EFAVFETTV-RGNPNPEVTWFINGHKM--DQGSPGVKIEAHNHDHKLTIDSAQY--AGTV 1015
Query: 179 QCIARNAAGTRES-----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
C A NA G E+ +A K P + D ++V F+ RV G+P P V
Sbjct: 1016 LCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTV 1075
Query: 234 LWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVY 290
W G RV++ + DGS+++ N+ + D GE A NS G+ LTV
Sbjct: 1076 TWYLK-GEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134
Query: 291 DPP---SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P +L P S+ VE G+ A F+ A G P PT WSV G + +R +
Sbjct: 1135 KKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDES 1194
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAV--NYAGSSFVRGKLTV 389
V DG ++LTI+ N + S V N G+ +LT+
Sbjct: 1195 TV-DGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTI 1237
Score = 99.5 bits (237), Expect = 1e-20
Identities = 125/500 (25%), Positives = 188/500 (37%), Gaps = 54/500 (10%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA-GGLFFLRATHGRVHS 78
D V TL C G P P + W K GV++ D ++ A G LR + S
Sbjct: 5079 DTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAK-KS 5137
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPR 133
D G Y A N G+A S + + V E+ F + ++ + GD + R
Sbjct: 5138 DIGQYRVTAKNEAGSATS-DCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFN-VKVR 5195
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
G P+P + W NG + FD + + GN L I+D R+ D G +CIA+N GT E+
Sbjct: 5196 GLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDET 5255
Query: 192 AIATLK-----------IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
+ + P D G + +C V +P +V W +
Sbjct: 5256 VCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGK 5315
Query: 241 G-GNMPLGRVKVLDDGSLRLDNVIL--ADEGEYSCEAENSVG--AVSASGYLTVYD---- 291
+ ++ DG+ R+ + +D G Y C A N +G A+ + + +
Sbjct: 5316 KIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEE 5375
Query: 292 ------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
P IN V G R +C P ++ W +G P + +
Sbjct: 5376 EKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG-----LPLRADSRTS 5430
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG----SSFVRGKLTVTS-DDDRPPPII 400
DG L IND+ + D C A N G S V K+ + P
Sbjct: 5431 IQYEEDGTATLAINDSTEEDI-GAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFF 5489
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV---TNDG--TLVLK 455
T G + C P P I WY G+ L++N R V + DG +L +
Sbjct: 5490 TKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVN 5548
Query: 456 DLDKSDSGTYTCVASSRHGK 475
+ SD G Y C A + HGK
Sbjct: 5549 ESTMSDEGIYRCEAENAHGK 5568
Score = 97.5 bits (232), Expect = 5e-20
Identities = 118/443 (26%), Positives = 172/443 (38%), Gaps = 64/443 (14%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + +AP ++E ++ + Q L C+ G P P I+W+K G V ++ +
Sbjct: 5807 DVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIES 5866
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLRE----E 109
DAG Y C A N+YG+AR+ R + +RE
Sbjct: 5867 PDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPG 5926
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
F +++ GD+V ECL P G+P P++ W K+G L D +M G L++
Sbjct: 5927 FTTPLTIRRAKPGDSVTFECL-PFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLIL 5985
Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKI-------------------HIKPYLITGP 208
D G ++C+A N GT S A L I KP + G
Sbjct: 5986 SDVTFLSEGYFRCVATNEHGT-ASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGL 6044
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDD----GSLRLDNV 262
++ G+ V G P P V W + G+ P G+ + D L + N
Sbjct: 6045 YNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNA 6104
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---------NLSPNSV-NVESGNVAR- 311
DEGEYS EA N +G+ G L + P I P V +++ +V
Sbjct: 6105 SPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNH 6164
Query: 312 ----FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
F C G P P + W G + I PG R K + G L I DT D+
Sbjct: 6165 MPTIFDCLVVGHPAPEVEWFHNGKK--IVPG-GRIKIQSCG--GGSHALIILDTTLEDA- 6218
Query: 368 NTIVCSAVNYAGSSFVRGKLTVT 390
V +A N GS+ L VT
Sbjct: 6219 GEYVATAKNSHGSASSSAVLDVT 6241
Score = 96.3 bits (229), Expect = 1e-19
Identities = 125/542 (23%), Positives = 206/542 (38%), Gaps = 42/542 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLFFL 69
P ++ P + + + G P P + WY ++ + + G +
Sbjct: 2269 PEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSI 2328
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
R + + G EA N G ++ A L V E +F + +Q +G+ V
Sbjct: 2329 RIQKPLMEHN-GTIRVEAENVSGKVQA-TAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKF 2386
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAA 186
G PEP+V W NG+ + + + DG + + I AG C A N
Sbjct: 2387 TA-NVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPV 2445
Query: 187 GT--RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243
G+ R+ +A K+ P ED + G ++ P P + W + G
Sbjct: 2446 GSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKD-GVEI 2504
Query: 244 MPLGRVKVLD--DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPS 294
G K+++ DGSL+L L D+G + +AE+ G S L V P+
Sbjct: 2505 TSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPA 2564
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+N+ G+ TG P P + W + G + + + D + A +GV
Sbjct: 2565 FQSDIAPINLTEGDTLECKLLITGDPTPFVKWYI-GTQLVC---ATEDTEISNA--NGVY 2618
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKS 413
+ I+ D I C A N AG G L V + P P+ + T
Sbjct: 2619 TMKIHGVTA-DMTGKIKCVAYNKAGEVSTEGPLKVVA----PIPVEFETSLCDATCREGD 2673
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
+ PEP+++WY G+ L ++ + ++ T+ +KD+ SG C A
Sbjct: 2674 TLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAI 2733
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT---DTSVTLSWSQN 527
+ +GK LLV P ++V + G TK + H V D +L+W N
Sbjct: 2734 NEYGKATSEATLLVLPRGEPPDFLEWLSNVRARTG--TK-VVHKVVFTGDPKPSLTWYIN 2790
Query: 528 NK 529
NK
Sbjct: 2791 NK 2792
Score = 92.7 bits (220), Expect = 1e-18
Identities = 126/525 (24%), Positives = 200/525 (38%), Gaps = 43/525 (8%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C G P P + W + +H L G D GVY + N +G
Sbjct: 669 CEVEGWPEPELVWLVDDQ-PLRPSHDFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFG 727
Query: 93 TARSRNATLHVAV------LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
+ S+ A L V + EF+ E + +G+ V + + G P P + W NG
Sbjct: 728 SIESK-AELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVIT-GDPNPEIIWFING 785
Query: 147 QTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
+ L + DG L I+D + G C N G+ S LK+ + P
Sbjct: 786 KPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSA-SCDGRLKVRVPPAPP 844
Query: 206 T--GP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKVLD-DGSLRL 259
T P ED Q S+V F+ V G P P + + + G + G V+++ DG R+
Sbjct: 845 TFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTF--TLCGKELKNGEEGVEIVGHDGFYRI 902
Query: 260 D--NVIL-ADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
N + +GE +A+N G + LTV P+ V++G
Sbjct: 903 SIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEF 962
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A F T G P P + W + G++ + G K A +T+ D T
Sbjct: 963 AVFETTVRGNPNPEVTWFINGHK--MDQGSPGVKIEAHNHDHKLTI------DSAQYAGT 1014
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
++C A N G + +L V + + + PP ++T + + VF P+P
Sbjct: 1015 VLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPT 1074
Query: 429 IAWYFEGEALIQNHRRNVTN-DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
+ WY +GE L Q+ R + DG+ + +K++ D+G VA++ G L V
Sbjct: 1075 VTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134
Query: 486 -SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
P P R ++ G H T WS N +
Sbjct: 1135 KKPFAPEFD-LRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGR 1178
Score = 92.7 bits (220), Expect = 1e-18
Identities = 117/517 (22%), Positives = 201/517 (38%), Gaps = 69/517 (13%)
Query: 32 NCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRATHGRVHSDAGVYWCEATNS 90
N + G P P ++W+ G+ + D ++ A G + L R D G C A N
Sbjct: 5191 NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVR-EEDFGTLKCIAKNE 5249
Query: 91 YGTARS----RNATLHVAVLREEFRLEPE------SKQSAQGDTVVLECLPPRGSPEPNV 140
GT + + H R++ R P ++ GD + +EC +P V
Sbjct: 5250 NGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVD-ANPTAEV 5308
Query: 141 YWKKNGQTLLFDGDSRM-HLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
W K+G+ + + + + VDG + I ++D G Y C+A N G E+ AT ++
Sbjct: 5309 EWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQ-ATYQV 5367
Query: 199 HIKPYL-----------ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
I ++ I P ED G + C+V P V+W + +PL
Sbjct: 5368 EILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG----LPL 5423
Query: 247 GR-----VKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------- 292
++ +DG+ L +++ D G Y C A N+ G ++ S + V P
Sbjct: 5424 RADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE 5483
Query: 293 ---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P + + G+ C TG P P + W G + R +
Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ---LLRNGPRTVIETSP- 5539
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---------GKLTVTSDDDRPPPII 400
DG LT+N++ +D C A N G + + GK D+ PP
Sbjct: 5540 -DGSCSLTVNESTMSDE-GIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKF 5597
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLK 455
S+ ++ + ++ C P P + W +G LI++ R +N+ + L +K
Sbjct: 5598 ILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIK 5657
Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+ D GTY CVA++ +G + +D + +
Sbjct: 5658 NATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGV 5694
Score = 91.5 bits (217), Expect = 3e-18
Identities = 110/474 (23%), Positives = 186/474 (39%), Gaps = 49/474 (10%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
+P ++WYK + ++H G + A + D Y +N+ G S
Sbjct: 4898 APVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSS 4957
Query: 98 NATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
A V VL+ L+ + Q V L+ + G P+ + W KNGQ L D D
Sbjct: 4958 AALTVVKPNVLKIVDGLKDVDVEEPQ--PVELK-VKVEGIPKV-IKWYKNGQELKPDADG 5013
Query: 156 RM--HLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--- 208
+ G +L I ++++D G Y+ + N G S +H+K + P
Sbjct: 5014 FKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSV---VHVKSAKSSEPTSG 5070
Query: 209 -------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLR 258
+D + G +T QC + G+P P+V+W + + RV + +LR
Sbjct: 5071 ANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLR 5130
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARF 312
+ + +D G+Y A+N G+ ++ +TV + P + + G+ F
Sbjct: 5131 IRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEF 5190
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
G P+PT+ W + G P D+ + DG LTI D + D T+ C
Sbjct: 5191 NVKVRGLPKPTLQWFLNG-----IPIKFDDRITLDDMADGNYCLTIRDVREEDF-GTLKC 5244
Query: 373 SAVNYAGSSFV-------RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
A N G+ G + DD R PP ++ +P+ C P
Sbjct: 5245 IAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANP 5304
Query: 426 EPIIAWYFEGEALIQNHRRNVTN--DGTLVLK--DLDKSDSGTYTCVASSRHGK 475
+ W+ +G+ + + N DG +K ++SD G Y CVA + G+
Sbjct: 5305 TAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQ 5358
Score = 90.2 bits (214), Expect = 8e-18
Identities = 118/480 (24%), Positives = 194/480 (40%), Gaps = 35/480 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + + G + L
Sbjct: 4400 PEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEI 4456
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ ++ D Y +N G A S +A L V + E + +G VL+
Sbjct: 4457 PNAQL-DDTADYKVVVSNDAGDADS-SAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVET 4514
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAG- 187
+ E + W KNG+ + D DG N LVI DA DA Y+ + + G
Sbjct: 4515 NKKPKE--IKWYKNGKEIT-PSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGN 4571
Query: 188 TRESAIA-TLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242
T +S+ A T+K+ K P +I G ED V GS + + G P V W ++ G
Sbjct: 4572 TADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSP-KTVKWYKNGKELPGA 4630
Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP- 299
+++ +DD L + + ++ D G+Y E N G+ ++SG +TV +P L P
Sbjct: 4631 AAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-EPKITFLKPL 4689
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
++ G A F+ +P + W G I P ++ D L I
Sbjct: 4690 KDQSITEGENAEFSVETNTKPR-IVKWYKNGQE--IKP---NSRFIIEQKTDTKYQLVIK 4743
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
+ ++D+ +T N AG + +LTV I+ G +Q + + VF
Sbjct: 4744 NAVRDDA-DTYKIVLENTAGEAESSAQLTVKKAKAGLCKIV-KGLEDQVVAKGAKMVFEV 4801
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTN-DGT---LVLKDLDKSDSGTYTCVASSRHGK 475
PE + W + + + D T L++ D D+G YT + GK
Sbjct: 4802 KIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGK 4860
Score = 88.2 bits (209), Expect = 3e-17
Identities = 79/284 (27%), Positives = 116/284 (40%), Gaps = 10/284 (3%)
Query: 30 TLNCRA--GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
TL C+ G P+P ++WY G LV + I A G++ ++ HG G C A
Sbjct: 2579 TLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMK-IHGVTADMTGKIKCVA 2637
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + VA + EF +GDT+ L + G PEP V W NG+
Sbjct: 2638 YNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAV-LLGEPEPVVSWYVNGK 2696
Query: 148 TLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYL 204
L + ++H G + I+D +G+ C A N G T E+ + L P
Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVI 263
+ +V A+TG+ V + GDP P + W + N L + D S N
Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816
Query: 264 LAD--EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
D GE C+AEN G VS + + Y + S + E
Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAE 2860
Score = 86.6 bits (205), Expect = 9e-17
Identities = 98/460 (21%), Positives = 167/460 (36%), Gaps = 28/460 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P D V + G P P++ W G V + ++ G +
Sbjct: 2365 EVPKFTTNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTI 2424
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVL 127
+ AG CEATN G+ + R+ L V + + F E + +G+ ++
Sbjct: 2425 EIS-AVTPEQAGELSCEATNPVGS-KKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLM 2482
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNA 185
+ P+P + W K+G + DG ++ + G+L + + D GR A +
Sbjct: 2483 DAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESE 2542
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV--TFQCR--VGGDPLPDVLW----RR 237
G E + + + +P + +A + T +C+ + GDP P V W +
Sbjct: 2543 FGVAECSASLGVVKGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQL 2602
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
+ + + ++++ V G+ C A N G VS G L V P +
Sbjct: 2603 VCATEDTEISNANGVY--TMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEF 2660
Query: 298 SPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+ G+ + G PEP + W V G + K H+ G
Sbjct: 2661 ETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKK---LEESQNIKIHSEK---GTYT 2714
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+TI D D +VC A+N G + L V + PP SN +
Sbjct: 2715 VTIKDITC-DYSGQVVCEAINEYGKATSEATLLVLPRGE--PPDFLEWLSNVRARTGTKV 2771
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVL 454
V P+P + WY + ++ + VT+D T L
Sbjct: 2772 VHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTL 2811
Score = 86.2 bits (204), Expect = 1e-16
Identities = 80/296 (27%), Positives = 130/296 (43%), Gaps = 31/296 (10%)
Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAG-GLFFLRATHG 74
+PL+V + L G+P P + W+K + + ++H G G L
Sbjct: 3489 RPLEVR--EQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQA 3546
Query: 75 RVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R D GVY C+ATN G A++ N + + F + + QG L +
Sbjct: 3547 R-GEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAEL-VVRVE 3604
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGN----LVIQDARQTDAGRYQCIARNAAG 187
G PEP V W K+G + D H+++ G N LVI+D D G+Y C A N AG
Sbjct: 3605 GKPEPEVKWFKDGVPIAIDNQ---HVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAG 3661
Query: 188 TRESAIATLKI-----------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
++ + LKI +KP I ++ A G +V +C+V + P + +
Sbjct: 3662 -KDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFF 3720
Query: 237 RSAGGGNMPLG-RVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ + +++VL+DG+++L N D G Y CEA N G + + L +
Sbjct: 3721 KNDQPVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776
Score = 81.0 bits (191), Expect = 5e-15
Identities = 123/534 (23%), Positives = 198/534 (37%), Gaps = 37/534 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP ++ + V + A C+ G+ P ++W+K G + D
Sbjct: 4017 APGFFKELSAIQVKETETAKFECKVSGT-KPDVKWFKDGTPLKEDKRVHFESTDDGTQRL 4075
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D G Y E +N G A S+ V + + QG ++L +
Sbjct: 4076 VIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLS-V 4134
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCI-ARNAAG 187
G P+ V W K +T+ +++ V L I+ A +D G Y+ + + ++
Sbjct: 4135 EVEGKPK-TVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFS 4193
Query: 188 TRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
SA T+ KI + P G D G+ + + + G P DV W ++ G
Sbjct: 4194 VESSATVTVTKAAEKISL-PSFKKGLADQSVPKGTPLVLEVEIEGKP-KDVKWYKN--GD 4249
Query: 243 NMPLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
+ G+V+ L +G RL + D GEYS A N G + + + V P I
Sbjct: 4250 EIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLV 4309
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
V+ G A F G P + W G I ++D DG L I +
Sbjct: 4310 PTTVKQGETATFNVKVKG-PVKGVKWYKNGKE--IPDAKTKDN------GDGSYSLEIPN 4360
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDD--DRPPPIITNGPSNQTLPIKSMAVF 417
D+ + V + N AG + LTV +DD D+ P I +G T+ A F
Sbjct: 4361 AQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATF 4419
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475
+ P + WY G+ I N + DG +L + + D+ Y V S+ G
Sbjct: 4420 N-VKVKGPVKQVKWYKNGKE-IPNAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGD 4477
Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
S AL V P I + + + +P + + W +N K
Sbjct: 4478 ADSSAALTVKL---PGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGK 4528
Score = 80.6 bits (190), Expect = 6e-15
Identities = 102/403 (25%), Positives = 167/403 (41%), Gaps = 33/403 (8%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA-GGL 66
G+AP + D + + ++ + P P I W K GV + SD H I+ G
Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQG 122
L ++ D G +A + +G A +A+L V + + F+ + +G
Sbjct: 2520 LKLSILQTKLE-DKGRITIKAESEFGVAEC-SASLGVVKGRPMAKPAFQSDIAPINLTEG 2577
Query: 123 DTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQC 180
DT LEC L G P P V W Q + D+ + +G + I G+ +C
Sbjct: 2578 DT--LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKC 2635
Query: 181 IARNAAGTRESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+A N AG S LK+ + P + T D + G ++ + + G+P P V W
Sbjct: 2636 VAYNKAG-EVSTEGPLKV-VAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693
Query: 238 SAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---D 291
+ G +K+ + ++ + ++ G+ CEA N G ++ L V +
Sbjct: 2694 N-GKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGE 2752
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP ++V +G TG P+P++ W + N+ I+ + D Y T V D
Sbjct: 2753 PPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYIN-NKEIL----NSDLY--TIVTD 2805
Query: 352 GVT-VLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSD 392
T LTIN + + I+C A N AG S +T TSD
Sbjct: 2806 DKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTANMITYTSD 2848
Score = 75.8 bits (178), Expect = 2e-13
Identities = 99/334 (29%), Positives = 140/334 (41%), Gaps = 50/334 (14%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSI 60
D + G+AP PL + A+ T C G+P P+I+W K G+ + SD +
Sbjct: 5916 DSSIREGKAPGFTT-PLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKME 5974
Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-------EEFRLE 113
A G L + S+ G + C ATN +GTA S A L + R E E
Sbjct: 5975 AAADGTQRLILSDVTFLSE-GYFRCVATNEHGTA-STKAELVIEGDRTIGSRPLPEVNGE 6032
Query: 114 PES----------KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--- 160
PE S VV + G P P V W K+GQ ++ DG ++
Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092
Query: 161 DGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---------PE 209
+ G +LVI +A D G Y A N G+ ++ +L I I+P I P
Sbjct: 6093 ERGIHHLVIVNASPDDEGEYSLEATNKLGSAKTE-GSLNI-IRPRHIADADERGGMPFPP 6150
Query: 210 DVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG----SLR 258
V Q + F C V G P P+V W + G +P GR+K+ G +L
Sbjct: 6151 GFVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHN-GKKIVPGGRIKIQSCGGGSHALI 6209
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ + L D GEY A+NS G+ S+S L V P
Sbjct: 6210 ILDTTLEDAGEYVATAKNSHGSASSSAVLDVTVP 6243
Score = 75.4 bits (177), Expect = 2e-13
Identities = 74/289 (25%), Positives = 114/289 (39%), Gaps = 23/289 (7%)
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DG--SLRLDNVILADEGEYSCE 273
SS +V G PLPD+ W + + D DG ++ +D V + D G Y+C
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 274 AENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
A N G S S + V PP+ + G+V F C G PEP + W
Sbjct: 623 ATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWL 682
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
V+ R + +DG T L I D +D+ N GS + +
Sbjct: 683 VDDQPL-------RPSHDFRLQYDGQTAKLEIRDAQPDDT-GVYTVKIQNEFGSIESKAE 734
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHR- 443
L V +D D+ + + + ++ T P P I W+ G+ L ++ +
Sbjct: 735 LFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKV 794
Query: 444 RNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+ ++ DG L +KD+ + G TC S+R G G L V P P
Sbjct: 795 KFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP 843
Score = 74.5 bits (175), Expect = 4e-13
Identities = 119/491 (24%), Positives = 192/491 (39%), Gaps = 40/491 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFL 69
P II+ D V+ P L GSP ++WYK G + ++I ++
Sbjct: 4588 PKIIKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV 4646
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLE 128
V D G Y E N G+A N++ + V + L+P QS +G+ E
Sbjct: 4647 LEIPSSVVEDTGDYKVEVANEAGSA---NSSGKITVEPKITFLKPLKDQSITEGENA--E 4701
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARN 184
+ V W KNGQ + +SR + + LVI++A + DA Y+ + N
Sbjct: 4702 FSVETNTKPRIVKWYKNGQEI--KPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759
Query: 185 AAGTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
AG ES+ K L + G ED V G+ + F+ ++ G+P DV W R A
Sbjct: 4760 TAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEP-EDVRWLRDANV 4818
Query: 242 GNMPLGRV-KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
+ + + +DD + RL + L D GEY+ E N G + V + P I
Sbjct: 4819 ISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRG 4878
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
++ + G+ F + P + W N I P A + L I
Sbjct: 4879 LENIEIPEGDDDVFKVEVSA-PVRQVKW--YKNDQEIKP---NSHLEAKKIGPKKYELAI 4932
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N +D + V + N AG LTV + I +G + +
Sbjct: 4933 NRAQLDDGADYKVVLS-NAAGDCDSSAALTVVKPNVLK---IVDGLKDVDVEEPQPVELK 4988
Query: 419 CTAICTPEPIIAWYFEGEAL------IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
P+ +I WY G+ L + + + + +L + KSD G Y V +
Sbjct: 4989 VKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGND 5047
Query: 473 HGKYVWSGALL 483
G+ V+SG+++
Sbjct: 5048 KGE-VYSGSVV 5057
Score = 72.5 bits (170), Expect = 2e-12
Identities = 87/393 (22%), Positives = 159/393 (40%), Gaps = 30/393 (7%)
Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
V+ +F + + ++ +G + V EC+ P + W K+G+ + R+ G
Sbjct: 2884 VMAPKFITKIKDTKAKKGHSAVFECVVP-DTKGVCCKWLKDGKEIELIARIRVQTRTGPE 2942
Query: 165 ------LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIK------PYLITGPED 210
LV+ + DAG+Y CI N AG T E+ + ++ K P I +D
Sbjct: 2943 GHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQD 3002
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
+T V +C+V G+P P V W V+ ++ + + + L+ +G+
Sbjct: 3003 KTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTITSSELSHQGK 3062
Query: 270 YSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
Y+C AEN+ G +LTV + P + + G +C+ G P+P + +
Sbjct: 3063 YTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYS 3122
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVT--VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
T + ++ A T + I+ K D + A N G++ K
Sbjct: 3123 FSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDI-VSYKAIATNSIGTATSTSK 3181
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NH-- 442
+T + P+ G ++ K + P + W+ + + + + NH
Sbjct: 3182 ITTKVE----APVFEQGLKKTSVKEKEEIKME-VKVGGSAPDVEWFKDDKPVSEDGNHEM 3236
Query: 443 RRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
++N T TLV+K +D+G YT AS+ G
Sbjct: 3237 KKNPETGVFTLVVKQAATTDAGKYTAKASNPAG 3269
Score = 72.5 bits (170), Expect = 2e-12
Identities = 119/493 (24%), Positives = 193/493 (39%), Gaps = 42/493 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + G + L
Sbjct: 4302 PEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD--NGDGSYSLEI 4358
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSA------QGDT 124
+ +V DA Y +N G A S +A L V + + + +++PE QG+T
Sbjct: 4359 PNAQVE-DAADYKVVVSNDAGDADS-SAALTVKLADDGKDKVKPEIVSGLIPTTVKQGET 4416
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ +G P V W KNG+ + + ++ + +L I +A+ D Y+ + N
Sbjct: 4417 ATFN-VKVKG-PVKQVKWYKNGKEIP-NAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSN 4473
Query: 185 AAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
AG +S+ A T+K+ ++ G ED G Q P ++ W ++ G
Sbjct: 4474 DAGDADSSAALTVKLP-GIAIVKGLEDAEVPKGKKAVLQVETNKKP-KEIKWYKN-GKEI 4530
Query: 244 MPLGRVKVLDDGSLRLDNVILA----DEGEYSCEAENSVG-AVSASGYLTVYDP---PSI 295
P + + DG + VI D EY + G +S LTV P P I
Sbjct: 4531 TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKI 4590
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
V G+ + +G P+ T+ W G PG + + D V
Sbjct: 4591 IKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKE---LPGAAAKTIKIQKIDDNKYV 4646
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L I + D+ + V N AGS+ GK+TV P +Q++ A
Sbjct: 4647 LEIPSSVVEDTGDYKV-EVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGENA 4700
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
F P I+ WY G+ + N R + LV+K+ + D+ TY V +
Sbjct: 4701 EFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759
Query: 472 RHGKYVWSGALLV 484
G+ S L V
Sbjct: 4760 TAGEAESSAQLTV 4772
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 15/207 (7%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG---QTLLFDGDSRMHLVDGGN--LVIQD 169
E + A+ DT+ + L G P+P++ WK G T +++ G L I
Sbjct: 6417 EKRYCAENDTLTI-VLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITG 6475
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
+ + G+YQC A+N G + I + + +P I + + + RV G+P
Sbjct: 6476 FSKENVGQYQCFAKNDYGDAQQNIM-VDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P++ W + + R+K + DG SL +++ + D G YSC A N G + S
Sbjct: 6535 FPELKWMKE-WRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 6593
Query: 286 YLTVY---DPPSINLSPNSVNVESGNV 309
+TV D + L V +ES V
Sbjct: 6594 TVTVEAEGDYNDVELPRRRVTIESRRV 6620
Score = 64.1 bits (149), Expect = 6e-10
Identities = 94/423 (22%), Positives = 157/423 (37%), Gaps = 33/423 (7%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
S AP ++ D TV + A G+P+P + W+ G + + + A
Sbjct: 942 SRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHD 1001
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-------SKQSA 120
+ AG C A N+ G ++ + VL E + +P K
Sbjct: 1002 HKLTIDSAQY--AGTVLCRAENAVGRFETK---ARLVVLAPEKQKKPPKFVEILVDKTET 1056
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179
+TVV E + G P+P V W G+ L + DG + I++ + DAG +
Sbjct: 1057 VDNTVVFE-VRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115
Query: 180 CIARNAAGTRESAIATLKIHIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
+A N+ G+ E+ A L + KP+ P + + GS F G PLP W
Sbjct: 1116 AVATNSEGSDETK-AKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWS 1174
Query: 237 RSA-----GGGNMPLGRVKVLDDGS--LRLDNVILADEGEY---SCEAENSVGAVSASGY 286
+ G + R + DG+ L +D E + S AEN++GA
Sbjct: 1175 VNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQ 1234
Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTC--TATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
LT+ +P ++ ++ S V + PE T ++E + T +
Sbjct: 1235 LTI-EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEATTTITMETSLTST-KTTTMSTT 1292
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
T+ GVTV T +++ + I + S K+ V S D + P
Sbjct: 1293 EVTSTVGGVTVET-KESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVREGTP 1351
Query: 405 SNQ 407
+
Sbjct: 1352 KRR 1354
Score = 61.7 bits (143), Expect = 3e-09
Identities = 66/257 (25%), Positives = 93/257 (36%), Gaps = 16/257 (6%)
Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
+VG ++S T P S V A C G P P + W+ EG
Sbjct: 3801 TVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEV--- 3857
Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD--- 393
MS + A DG LT ++ + D+ C A N GS++ G + VT +
Sbjct: 3858 -EMSA-RVRAEHKDDGTLTLTFDNVTQADA-GEYRCEAENEYGSAWTEGPIIVTLEGAPK 3914
Query: 394 -DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DG 450
D P + + AV P+P + WY GE L + R + N DG
Sbjct: 3915 IDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDG 3974
Query: 451 T--LVLKDLDKSDSGTYTCVASSRHGKYVWSG-ALLVDSPINPNIHFFRAADVSSLPGPP 507
T L + + D Y C AS+ G VWS L V P FF+ +
Sbjct: 3975 TQRLTVTNAKLDDMDEYRCEASNEFGD-VWSDVTLTVKEPAQVAPGFFKELSAIQVKETE 4033
Query: 508 TKPITHNVTDTSVTLSW 524
T V+ T + W
Sbjct: 4034 TAKFECKVSGTKPDVKW 4050
Score = 60.5 bits (140), Expect = 7e-09
Identities = 89/376 (23%), Positives = 149/376 (39%), Gaps = 27/376 (7%)
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
D +G +A NAAG+ E+ LK+ P PE VT V D
Sbjct: 1944 DTTMFGSGTVSVVASNAAGSVETK-TELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMD 2002
Query: 229 --PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVGAVSA 283
L L++ G + G+ V ++I+ D G+ + EA N VG+ +
Sbjct: 2003 VIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSES 2062
Query: 284 SGYLTVYDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
S LTV P P + P SV ++ A F T +G P PT+ W++ N I+
Sbjct: 2063 SAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTI--NEKIV----E 2116
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP--PP 398
+ T + V L I++ K + T+ +A N AG + L V + P
Sbjct: 2117 ESRTITTIKTEDVYTLKISNA-KIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGT--LVL 454
+T+ +++ P++ +P ++W G+ L ++ V + DGT + +
Sbjct: 2176 QLTDKVADEGEPLRWNLELDGP---SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTI 2232
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514
+ SGT T A + G+ S + V+ N F +A + +
Sbjct: 2233 AEAKPEMSGTLTAKAKNAAGECETSAKVTVNGG-NKKPEFVQAPQNHETTLEESVKFSAI 2291
Query: 515 VTDTSV-TLSWSQNNK 529
VT + ++W NNK
Sbjct: 2292 VTGKPMPNVTWYLNNK 2307
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 12/171 (7%)
Query: 24 ARHQPATLNCRAGGSPSPAIRW-YKG-GVLVVSDTHR-SILPAGGLFFLRATHGRVHSDA 80
A + T+ G P P I+W ++G + S T + + GG A G +
Sbjct: 6422 AENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENV 6481
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N YG A+ +N + +A R F ++P ++ + + G P P +
Sbjct: 6482 GQYQCFAKNDYGDAQ-QNIMVDLAT-RPNF-IQPLVNKTFSSAQPMRMDVRVDGEPFPEL 6538
Query: 141 YWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG 187
W K + ++ SR+ V G +L+I D D+G Y C+A N AG
Sbjct: 6539 KWMKEWRPIV--ESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAG 6587
Score = 39.9 bits (89), Expect = 0.011
Identities = 21/83 (25%), Positives = 36/83 (43%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ ++ T + QP ++ R G P P ++W K +V + + G
Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566
Query: 72 THGRVHSDAGVYWCEATNSYGTA 94
+ + D+G+Y C A N G A
Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQA 6589
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P P + W E ++++ R DG +L++ D DSG Y+CVA + G+ S
Sbjct: 6534 PFPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 6593
Query: 481 ALLVDS 486
+ V++
Sbjct: 6594 TVTVEA 6599
>AF003131-2|AAV34800.1| 7441|Caenorhabditis elegans Uncoordinated
protein 89, isoform f protein.
Length = 7441
Score = 146 bits (354), Expect = 8e-35
Identities = 178/689 (25%), Positives = 281/689 (40%), Gaps = 110/689 (15%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAG 64
VT+ + P + DV QP L C+ SP P + WYK G +V SD + L
Sbjct: 5055 VTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPD 5114
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLREEFR--- 111
G+ L V+ D G+Y ATN GTA+ R++ + R+ F
Sbjct: 5115 GVATLLIP-SCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANK 5173
Query: 112 ----LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-- 164
+EP E+ + + + L C G P+P + W K+G+ + G R+ L++ +
Sbjct: 5174 APKLMEPLENIRIPEKQSFRLRC-KFSGDPKPTIKWFKDGERVFPYG--RLQLIESPDGV 5230
Query: 165 --LVIQDARQTDAGRYQCIARNAAGTRESA--IATLKIHIKPYLI------------TGP 208
LV+ A + DAG Y+C+A N G+ ++ + ++ KP I T P
Sbjct: 5231 CELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTP 5290
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL--DNVI 263
+ A+ G SVTF+C G+P P + W + G ++K+ DG+ RL +V
Sbjct: 5291 LTIRRAKPGDSVTFECLPFGNPFPSIKWLKD-GLELFSDEKIKMEAAADGTQRLILSDVT 5349
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDP--------PSINLSPN-----------SVNV 304
EG + C A N G S L + P +N P ++++
Sbjct: 5350 FLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMSI 5409
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
GNV ATG P PT+ W +G + I+ G + T G+ L I + +
Sbjct: 5410 HEGNVVEMIVCATGIPTPTVKWYKDG-QEIVGDGPDGKRVIFTDE-RGIHHLVIVNASPD 5467
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLT------VTSDDDRP----PPIITNGPSNQTLPIKSM 414
D A N GS+ G L + D+R PP N+ +
Sbjct: 5468 D-EGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMP 5526
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVAS 470
+F C + P P + W+ G+ ++ R + + G L++ D D+G Y A
Sbjct: 5527 TIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATAK 5586
Query: 471 SRHGKYVWSGALLVDSPINPNIHF---------------FRAADVSSLPGPPTK-PITHN 514
+ HG S L V P +I F F+ + +SLP PP + P
Sbjct: 5587 NSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKKLNTASLPTPPDRGPFIKE 5646
Query: 515 VTDTSVTLSWSQNNKIGSS-SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
VT +TLSW + + Y +E+ RE + W ++ + +
Sbjct: 5647 VTGHYLTLSWIPTKRAPPRYPQVTYVIEI--REL--------PEKQWSLLEYNIPEPVCK 5696
Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVS 602
V++L G +Y F VR EN +G+S PSP S
Sbjct: 5697 VRNLELGKSYQFRVRAENIYGISDPSPAS 5725
Score = 140 bits (339), Expect = 5e-33
Identities = 139/499 (27%), Positives = 208/499 (41%), Gaps = 62/499 (12%)
Query: 28 PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-PAGGLFFLRATHGRVHSDAGVYWCE 86
P + C +P+ + W+K G + H I G ++ SD GVY C
Sbjct: 4653 PMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFE-ESDIGVYMCV 4711
Query: 87 ATNSYGTARSRNATLHVAVL-------REEF--RLEP--ESKQSAQGDTVVLECLPPRGS 135
A N G A ++ AT V +L R E+ ++ P E K G + L C
Sbjct: 4712 AVNELGQAETQ-ATYQVEILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSC-KVDAI 4769
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGT-RESA 192
P +V W K+G L D + + + G L I D+ + D G Y+C+A NA GT S
Sbjct: 4770 PRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSC 4829
Query: 193 IATLKI---HIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGN 243
+K+ +K P+ G D+ A G S T +C V GDP P++ W R+ N
Sbjct: 4830 SVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRN 4889
Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY----------- 290
P ++ DG SL ++ ++DEG Y CEAEN+ G V
Sbjct: 4890 GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKM 4949
Query: 291 ---DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
PP L + ++V GNV C TG P P++ WS +G I SR ++ +
Sbjct: 4950 DEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLI---EDSRFEW-SN 5005
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSN 406
GV L I + +D T C A N GS+ K V DD ++T + P
Sbjct: 5006 EASKGVYQLRIKNATVHD-EGTYRCVATNENGSATT--KSFVRMDDGLGSGVVTASQPPR 5062
Query: 407 QTLPIKSMAV-------FPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDG--TLVLK 455
TL + + C +P P + WY +G + + R + + DG TL++
Sbjct: 5063 FTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIP 5122
Query: 456 DLDKSDSGTYTCVASSRHG 474
D G Y +A++ G
Sbjct: 5123 SCVYDDDGIYRVIATNPSG 5141
Score = 139 bits (336), Expect = 1e-32
Identities = 142/521 (27%), Positives = 221/521 (42%), Gaps = 71/521 (13%)
Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I PL D TV QP L+C+ P ++ WYK G+ + +D+ SI A +
Sbjct: 4745 INPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIN 4804
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---------QSAQGDT 124
D G Y C ATN++GT + + +++V V ++E + E E + +GD+
Sbjct: 4805 DSTEEDIGAYRCVATNAHGTINT-SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDS 4863
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGG-NLVIQDARQTDAGRYQCI 181
L+C G P P + W +NGQ LL +G + DG +L + ++ +D G Y+C
Sbjct: 4864 FTLKC-AVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 4921
Query: 182 ARNAAG-TRESAIATLKIHI----KPYLITGP--------EDVVAQTGSSVTFQCRVGGD 228
A NA G + A A +++ + KP + G D+ G+ + +C+V G
Sbjct: 4922 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGL 4981
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVS- 282
P P V W + GG + R + ++ S LR+ N + DEG Y C A N G+ +
Sbjct: 4982 PNPSVKWSKD-GGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATT 5040
Query: 283 ----------ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
SG +T PP L V G + C P P M W +G
Sbjct: 5041 KSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG-- 5098
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--- 389
I+ P D+ + DGV L I +D V A N +G++ +G TV
Sbjct: 5099 AIVTPS---DRIQISLSPDGVATLLIPSCVYDDDGIYRVI-ATNPSGTAQDKGTATVKKL 5154
Query: 390 --------TSD----DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
++D D P + N +P K C P+P I W+ +GE
Sbjct: 5155 PRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGER 5214
Query: 438 LIQNHRRNV--TNDGT--LVLKDLDKSDSGTYTCVASSRHG 474
+ R + + DG LV+ + D+G Y CVA + +G
Sbjct: 5215 VFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYG 5255
Score = 136 bits (328), Expect = 1e-31
Identities = 127/499 (25%), Positives = 210/499 (42%), Gaps = 32/499 (6%)
Query: 7 TSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PA 63
T EAP + EQ L T V + + + GGS +P + W+K V D + + P
Sbjct: 2544 TKVEAP-VFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDDKPVSEDGNHEMKKNPE 2601
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQG 122
G+F L +DAG Y +A+N GTA S A + ++ + F E + +
Sbjct: 2602 TGVFTLVVKQAAT-TDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKIN 2660
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQ 179
+T L + +G P+P+V W K+GQ + D + V+G ++ I+DAR D+G+Y
Sbjct: 2661 ETATLS-VTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYA 2719
Query: 180 CIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
C A N AG E+ A +K + P + + + S T +V G P P V W +
Sbjct: 2720 CRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFK 2779
Query: 238 SAGGGNMP----LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYD- 291
++ + + + SL +++ D G YSC A N G A++ + + + D
Sbjct: 2780 DDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS 2839
Query: 292 -PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
PP + V T G P P + W + ++ I + A
Sbjct: 2840 IPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEW-FKDDKPI---NIDNSHIFAKDEG 2895
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G LTI + + C A N AG + + V + + P + G +
Sbjct: 2896 SGHHTLTIKQA-RGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP--LFVQGLKPYEVE 2952
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTY 465
A PEP + W+ +G + +++ + G TLV+KD + +D G Y
Sbjct: 2953 QGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKY 3012
Query: 466 TCVASSRHGKYVWSGALLV 484
TC A+++ GK G L +
Sbjct: 3013 TCQATNKAGKDETVGELKI 3031
Score = 135 bits (327), Expect = 2e-31
Identities = 129/483 (26%), Positives = 199/483 (41%), Gaps = 34/483 (7%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + + G P P I WYK V + D + FF +D G Y C AT
Sbjct: 565 AKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMAT 624
Query: 89 NSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
N YG A S +A V + +E F + K+ +GD + EC G PEP + W
Sbjct: 625 NEYGQA-STSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFEC-EVEGWPEPELVWL 682
Query: 144 KNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL----- 196
+ Q L D R+ DG L I+DA+ D G Y +N G+ ES
Sbjct: 683 VDDQPLRPSHDFRLQ-YDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADP 741
Query: 197 -KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDD 254
K H+ P E V G V F+ + GDP P+++W + G +VK + +D
Sbjct: 742 DKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFIN-GKPLSESEKVKFISED 800
Query: 255 G--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNV 309
G L + +V +G +C+ N +G+ S G L V PP+ N V+ +
Sbjct: 801 GICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKST 860
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
F +G PEPT+ +++ G + ++ DG ++I +T +
Sbjct: 861 VVFEVDVSGWPEPTLTFTLCGKEL-----KNGEEGVEIVGHDGFYRISIPNTSMDKHDGE 915
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDD--RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
IV A N G++ R +LTV +++ R P +QT+ AVF T P P
Sbjct: 916 IVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNP 975
Query: 428 IIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
+ W+ G + Q + N + D +GT C A + G++ L+V
Sbjct: 976 EVTWFINGHKMDQGSPGVKIEAHNHDHKLTID-SAQYAGTVLCRAENAVGRFETKARLVV 1034
Query: 485 DSP 487
+P
Sbjct: 1035 LAP 1037
Score = 126 bits (303), Expect = 1e-28
Identities = 139/544 (25%), Positives = 222/544 (40%), Gaps = 78/544 (14%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GE P+ + +D+ R TL C G P P I+WY+ G L+ + I +
Sbjct: 4844 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC 4903
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREE-----------FRLEPE 115
+ SD G+Y CEA N++G A+++ AT HV A+ + E F LE
Sbjct: 4904 SLTVNESTMSDEGIYRCEAENAHGKAKTQ-ATAHVQMALGKTEKPKMDEGKPPKFILELS 4962
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-----LVIQDA 170
+ G+ + LEC G P P+V W K+G L+ DSR + + L I++A
Sbjct: 4963 DMSVSLGNVIDLEC-KVTGLPNPSVKWSKDGGPLI--EDSRFEWSNEASKGVYQLRIKNA 5019
Query: 171 RQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPE---------DVVAQTGSSVT 220
D G Y+C+A N G+ + + + + ++T + DV G +
Sbjct: 5020 TVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLK 5079
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDG--SLRLDNVILADEGEYSCEAEN 276
+C+V PLP+++W + G P R+++ DG +L + + + D+G Y A N
Sbjct: 5080 LECKVDASPLPEMVWYKD-GAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATN 5138
Query: 277 SVGAVSASGYLTVYDPP--------------SINLSP------NSVNVESGNVARFTCTA 316
G G TV P N +P ++ + R C
Sbjct: 5139 PSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKF 5198
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
+G P+PT+ W +G R +FP + DGV L ++ + D+ C A N
Sbjct: 5199 SGDPKPTIKWFKDGER--VFP---YGRLQLIESPDGVCELVVDSATRQDA-GGYRCVAEN 5252
Query: 377 YAGSSFVRGKLTVTSDDDRPPPI---ITNGPS-NQTLPIK-------SMAVFPCTAICTP 425
GS+ + V D +P I I G + T P+ F C P
Sbjct: 5253 TYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNP 5312
Query: 426 EPIIAWYFEGEALIQNH--RRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P I W +G L + + DGT L+L D+ G + CVA++ HG
Sbjct: 5313 FPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 5372
Query: 482 LLVD 485
L+++
Sbjct: 5373 LVIE 5376
Score = 124 bits (298), Expect = 5e-28
Identities = 126/498 (25%), Positives = 203/498 (40%), Gaps = 46/498 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLF 67
E P + + + V ++ ATL+ G P P++ W K G V +D+ I + G +
Sbjct: 2644 EKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSY 2703
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEF--RLEPESKQSAQGDT 124
+ R+ D+G Y C ATN G A++ N + ++ EF +L P + + T
Sbjct: 2704 SITIKDARLE-DSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTT 2762
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCI 181
+ ++ + G+PEP+V W K+ + D + V +L I DARQ D G Y C
Sbjct: 2763 LSVKVV---GTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCR 2819
Query: 182 ARNAAG--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
ARN AG + ++ I P + + ++ + V G P+P+V W +
Sbjct: 2820 ARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDD 2879
Query: 240 GGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
N+ + D+GS L + D G Y+C+A N G + + V +
Sbjct: 2880 KPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEA 2939
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV--F 350
P VE G A G+PEP + W +G I D H
Sbjct: 2940 PLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAI------DNQHVIEKKGE 2993
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--------TSDDDRPPPIITN 402
+G L I DT+ D C A N AG G+L + T+++ +P +
Sbjct: 2994 NGSHTLVIKDTNNADF-GKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKP---LFI 3049
Query: 403 GPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR-NVTNDGT--LVLKDL 457
P +T ++ V C P I ++ + + I H + V DG L +++
Sbjct: 3050 EPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNA 3109
Query: 458 DKSDSGTYTCVASSRHGK 475
K D G Y C A + GK
Sbjct: 3110 KKEDVGAYRCEAVNVAGK 3127
Score = 114 bits (275), Expect = 3e-25
Identities = 138/493 (27%), Positives = 199/493 (40%), Gaps = 41/493 (8%)
Query: 11 APYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
AP +PL D TV G P P + + G L + I+ G +
Sbjct: 842 APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYR 901
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP------ESKQSAQG 122
+ + + G +A N +GTA SR A L V EE R P E + G
Sbjct: 902 ISIPNTSMDKHDGEIVAKAQNEHGTAESR-ARLTVEQEEEESRSAPTFLKDIEDQTVKTG 960
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRY 178
+ V E RG+P P V W NG + D S ++ N L I A+ AG
Sbjct: 961 EFAVFETTV-RGNPNPEVTWFINGHKM--DQGSPGVKIEAHNHDHKLTIDSAQY--AGTV 1015
Query: 179 QCIARNAAGTRES-----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
C A NA G E+ +A K P + D ++V F+ RV G+P P V
Sbjct: 1016 LCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTV 1075
Query: 234 LWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVY 290
W G RV++ + DGS+++ N+ + D GE A NS G+ LTV
Sbjct: 1076 TWYLK-GEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134
Query: 291 DPP---SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P +L P S+ VE G+ A F+ A G P PT WSV G + +R +
Sbjct: 1135 KKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDES 1194
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAV--NYAGSSFVRGKLTVTSDDDRPP-PIITNGP 404
V DG ++LTI+ N + S V N G+ +LT+ + +PP P +T
Sbjct: 1195 TV-DGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTI--EPKKPPAPKLTRDL 1251
Query: 405 SNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK---DLDKSD 461
QT+ +A F E W+ +G+ + V+ D + D
Sbjct: 1252 KLQTVNKTDLAHFEVVVEHATE--CKWFLDGKEITTAQGVTVSKDDQFEFRCSIDTTMFG 1309
Query: 462 SGTYTCVASSRHG 474
SGT + VAS+ G
Sbjct: 1310 SGTVSVVASNAAG 1322
Score = 112 bits (270), Expect = 1e-24
Identities = 127/493 (25%), Positives = 204/493 (41%), Gaps = 39/493 (7%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGG 65
T AP +E TV Q A L C+ G P P I+W K G V +S R+ G
Sbjct: 3172 TGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDG 3231
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---- 121
L +DAG Y CEA N YG+A + + L +++ E+ Q
Sbjct: 3232 TLTL-TFDNVTQADAGEYRCEAENEYGSAWTEGPI--IVTLEGAPKIDGEAPDFLQPVKP 3288
Query: 122 -----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTD 174
G+T VLE G P+P+V W KNG+ L ++ +D G L + +A+ D
Sbjct: 3289 AVVTVGETAVLEG-KISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDD 3347
Query: 175 AGRYQCIARNAAGTRESAIA-TLK--IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
Y+C A N G S + T+K + P + + + F+C+V G P
Sbjct: 3348 MDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECKVSGTK-P 3406
Query: 232 DVLWRRSAGGGNMPLGRV--KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYL 287
DV W + G RV + DDG+ RL ++ D+G Y E N G ++ L
Sbjct: 3407 DVKWFKD-GTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPL 3465
Query: 288 TVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
TV ++ + VNV G + G+P+ T+ W +G T+ S
Sbjct: 3466 TVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPK-TVKW-YKGTETV----TSSQTTK 3519
Query: 346 ATAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDR-PPPIITNG 403
V + L I + +D+ +V S +++ S +TVT ++ P G
Sbjct: 3520 IVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVES--SATVTVTKAAEKISLPSFKKG 3577
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDS 462
++Q++P + V P+ + WY G+ + ++ N L + D + D
Sbjct: 3578 LADQSVPKGTPLVLEVEIEGKPKD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDV 3636
Query: 463 GTYTCVASSRHGK 475
G Y+ A++ G+
Sbjct: 3637 GEYSVTAANEAGE 3649
Score = 107 bits (257), Expect = 5e-23
Identities = 120/492 (24%), Positives = 196/492 (39%), Gaps = 35/492 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P +++ P VT+ + A G P+P ++W +V + + ++ L+
Sbjct: 1435 PIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKI 1494
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLEC 129
++ ++ G A NS G S+ A L V V +F+ + K + +G+ +
Sbjct: 1495 SNAKI-EQTGTVKVTAQNSAG-QDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNL 1552
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNA 185
SP V W NGQ L + +VD G ++ I +A+ +G A+NA
Sbjct: 1553 ELDGPSPGTEVSWLLNGQPL--TKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNA 1610
Query: 186 AGTRE-SAIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
AG E SA T+ + KP + P++ SV F V G P+P+V W ++
Sbjct: 1611 AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLI 1670
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPSIN 296
+ + V S+R+ ++ G EAEN G V A+ L V + P
Sbjct: 1671 QSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFT 1730
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTV 355
+ + V+ G +FT G PEP++ W++ G P ++ DK DG
Sbjct: 1731 TNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDK-------DGEHT 1783
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I+ + + C A N GS +L V D P ++ + +
Sbjct: 1784 IEISAVTP-EQAGELSCEATNPVGSKKRDVQLAVKKVGD--APTFAKNLEDRLITEGELT 1840
Query: 416 VFPCTA-ICTPEPIIAWYFEG-EALIQNHRRNV-TNDGTLVLKDLDK--SDSGTYTCVAS 470
+ I P+P I W +G E H + V DG+L L L D G T A
Sbjct: 1841 LMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAE 1900
Query: 471 SRHGKYVWSGAL 482
S G S +L
Sbjct: 1901 SEFGVAECSASL 1912
Score = 106 bits (255), Expect = 8e-23
Identities = 116/490 (23%), Positives = 195/490 (39%), Gaps = 39/490 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP I D T + L C+ G P P + W + ++ ++ G+ +
Sbjct: 2352 KAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQES-ITVESVEGVERV 2410
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
T + S G Y C A N+ GT+++ A L V F E ++K+ + G+ +VL C
Sbjct: 2411 TITSSEL-SHQGKYTCIAENTEGTSKT-EAFLTVQGEAPVFTKELQNKELSIGEKLVLSC 2468
Query: 130 LPPRGSPEPNVYWKKNGQTLLFD----GDSRMHLV-DGGN----LVIQDARQTDAGRYQC 180
+GSP+P+V + +T + SR+ + D N +VI + D Y+
Sbjct: 2469 -SVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKA 2527
Query: 181 IARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS- 238
IA N+ GT S + T K+ P G + + + + +VGG PDV W +
Sbjct: 2528 IATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDD 2585
Query: 239 ---AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
+ GN + + +L + D G+Y+ +A N G +S V +
Sbjct: 2586 KPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEK 2645
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD- 351
P+ + V+ A + T G P+P++ W +G + D H A +
Sbjct: 2646 PTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQ------PVQTDSSHVIAKVEG 2699
Query: 352 -GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G +TI D DS C A N AG + V + PP S +
Sbjct: 2700 SGSYSITIKDARLEDS-GKYACRATNPAGEAKTEANFAVVK--NLVPPEFVEKLSPLEVK 2756
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEAL-IQN----HRRNVTNDGTLVLKDLDKSDSGTY 465
K + TPEP + W+ + + I N ++ +L + D + D G Y
Sbjct: 2757 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIY 2816
Query: 466 TCVASSRHGK 475
+C A + G+
Sbjct: 2817 SCRARNEAGE 2826
Score = 104 bits (249), Expect = 4e-22
Identities = 126/505 (24%), Positives = 191/505 (37%), Gaps = 36/505 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GEAP ++ + ++ + L+C GSP P + +Y +T + +
Sbjct: 2444 GEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEH 2503
Query: 69 LRA-THGRV------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
+ TH R+ D Y ATNS GTA S T + E E K+++
Sbjct: 2504 DQTNTHWRMVISQITKEDIVSYKAIATNSIGTATS---TSKITTKVEAPVFEQGLKKTSV 2560
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGG--NLVIQDARQTDAGRY 178
+ ++ G P+V W K+ + + DG+ M + G LV++ A TDAG+Y
Sbjct: 2561 KEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKY 2620
Query: 179 QCIARNAAGTRES---AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
A N AGT ES A T + KP + + + T V G P P V W
Sbjct: 2621 TAKASNPAGTAESSAEAEVTQSLE-KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEW 2679
Query: 236 RRSAGGGNMPLGRV--KVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
+ V KV G S+ + + L D G+Y+C A N G V
Sbjct: 2680 LKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVK 2739
Query: 292 ---PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
PP + + V+ + G PEP++ W + I K A
Sbjct: 2740 NLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVG 2799
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
F LTIND + D C A N AG + + D PP T
Sbjct: 2800 SFS----LTINDARQGDV-GIYSCRARNEAGEALTTANFGIIRDS--IPPEFTQKLRPLE 2852
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG----TLVLKDLDKSDSG 463
+ + T I TP P + W+ + + + I N ++G TL +K D G
Sbjct: 2853 VREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVG 2912
Query: 464 TYTCVASSRHGKYVWSGALLVDSPI 488
YTC A++ G+ + + V I
Sbjct: 2913 VYTCKATNEAGEAKTTANMAVQEEI 2937
Score = 99.5 bits (237), Expect = 1e-20
Identities = 125/500 (25%), Positives = 188/500 (37%), Gaps = 54/500 (10%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA-GGLFFLRATHGRVHS 78
D V TL C G P P + W K GV++ D ++ A G LR + S
Sbjct: 4439 DTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAK-KS 4497
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPR 133
D G Y A N G+A S + + V E+ F + ++ + GD + R
Sbjct: 4498 DIGQYRVTAKNEAGSATS-DCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFN-VKVR 4555
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
G P+P + W NG + FD + + GN L I+D R+ D G +CIA+N GT E+
Sbjct: 4556 GLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDET 4615
Query: 192 AIATLK-----------IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
+ + P D G + +C V +P +V W +
Sbjct: 4616 VCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGK 4675
Query: 241 G-GNMPLGRVKVLDDGSLRLDNVIL--ADEGEYSCEAENSVG--AVSASGYLTVYD---- 291
+ ++ DG+ R+ + +D G Y C A N +G A+ + + +
Sbjct: 4676 KIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEE 4735
Query: 292 ------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
P IN V G R +C P ++ W +G P + +
Sbjct: 4736 EKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG-----LPLRADSRTS 4790
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG----SSFVRGKLTVTS-DDDRPPPII 400
DG L IND+ + D C A N G S V K+ + P
Sbjct: 4791 IQYEEDGTATLAINDSTEEDI-GAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFF 4849
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV---TNDG--TLVLK 455
T G + C P P I WY G+ L++N R V + DG +L +
Sbjct: 4850 TKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVN 4908
Query: 456 DLDKSDSGTYTCVASSRHGK 475
+ SD G Y C A + HGK
Sbjct: 4909 ESTMSDEGIYRCEAENAHGK 4928
Score = 97.5 bits (232), Expect = 5e-20
Identities = 118/443 (26%), Positives = 172/443 (38%), Gaps = 64/443 (14%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + +AP ++E ++ + Q L C+ G P P I+W+K G V ++ +
Sbjct: 5167 DVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIES 5226
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLRE----E 109
DAG Y C A N+YG+AR+ R + +RE
Sbjct: 5227 PDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPG 5286
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
F +++ GD+V ECL P G+P P++ W K+G L D +M G L++
Sbjct: 5287 FTTPLTIRRAKPGDSVTFECL-PFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLIL 5345
Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKI-------------------HIKPYLITGP 208
D G ++C+A N GT S A L I KP + G
Sbjct: 5346 SDVTFLSEGYFRCVATNEHGT-ASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGL 5404
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDD----GSLRLDNV 262
++ G+ V G P P V W + G+ P G+ + D L + N
Sbjct: 5405 YNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNA 5464
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---------NLSPNSV-NVESGNVAR- 311
DEGEYS EA N +G+ G L + P I P V +++ +V
Sbjct: 5465 SPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNH 5524
Query: 312 ----FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
F C G P P + W G + I PG R K + G L I DT D+
Sbjct: 5525 MPTIFDCLVVGHPAPEVEWFHNGKK--IVPG-GRIKIQSCG--GGSHALIILDTTLEDA- 5578
Query: 368 NTIVCSAVNYAGSSFVRGKLTVT 390
V +A N GS+ L VT
Sbjct: 5579 GEYVATAKNSHGSASSSAVLDVT 5601
Score = 96.3 bits (229), Expect = 1e-19
Identities = 125/542 (23%), Positives = 206/542 (38%), Gaps = 42/542 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLFFL 69
P ++ P + + + G P P + WY ++ + + G +
Sbjct: 1629 PEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSI 1688
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
R + + G EA N G ++ A L V E +F + +Q +G+ V
Sbjct: 1689 RIQKPLMEHN-GTIRVEAENVSGKVQA-TAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKF 1746
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAA 186
G PEP+V W NG+ + + + DG + + I AG C A N
Sbjct: 1747 TA-NVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPV 1805
Query: 187 GT--RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243
G+ R+ +A K+ P ED + G ++ P P + W + G
Sbjct: 1806 GSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKD-GVEI 1864
Query: 244 MPLGRVKVLD--DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPS 294
G K+++ DGSL+L L D+G + +AE+ G S L V P+
Sbjct: 1865 TSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPA 1924
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+N+ G+ TG P P + W + G + + + D + A +GV
Sbjct: 1925 FQSDIAPINLTEGDTLECKLLITGDPTPFVKWYI-GTQLVC---ATEDTEISNA--NGVY 1978
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKS 413
+ I+ D I C A N AG G L V + P P+ + T
Sbjct: 1979 TMKIHGVTA-DMTGKIKCVAYNKAGEVSTEGPLKVVA----PIPVEFETSLCDATCREGD 2033
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
+ PEP+++WY G+ L ++ + ++ T+ +KD+ SG C A
Sbjct: 2034 TLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAI 2093
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT---DTSVTLSWSQN 527
+ +GK LLV P ++V + G TK + H V D +L+W N
Sbjct: 2094 NEYGKATSEATLLVLPRGEPPDFLEWLSNVRARTG--TK-VVHKVVFTGDPKPSLTWYIN 2150
Query: 528 NK 529
NK
Sbjct: 2151 NK 2152
Score = 92.7 bits (220), Expect = 1e-18
Identities = 117/517 (22%), Positives = 201/517 (38%), Gaps = 69/517 (13%)
Query: 32 NCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRATHGRVHSDAGVYWCEATNS 90
N + G P P ++W+ G+ + D ++ A G + L R D G C A N
Sbjct: 4551 NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVR-EEDFGTLKCIAKNE 4609
Query: 91 YGTARS----RNATLHVAVLREEFRLEPE------SKQSAQGDTVVLECLPPRGSPEPNV 140
GT + + H R++ R P ++ GD + +EC +P V
Sbjct: 4610 NGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVD-ANPTAEV 4668
Query: 141 YWKKNGQTLLFDGDSRM-HLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
W K+G+ + + + + VDG + I ++D G Y C+A N G E+ AT ++
Sbjct: 4669 EWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQ-ATYQV 4727
Query: 199 HIKPYL-----------ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
I ++ I P ED G + C+V P V+W + +PL
Sbjct: 4728 EILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG----LPL 4783
Query: 247 GR-----VKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------- 292
++ +DG+ L +++ D G Y C A N+ G ++ S + V P
Sbjct: 4784 RADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE 4843
Query: 293 ---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P + + G+ C TG P P + W G + R +
Sbjct: 4844 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ---LLRNGPRTVIETSP- 4899
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---------GKLTVTSDDDRPPPII 400
DG LT+N++ +D C A N G + + GK D+ PP
Sbjct: 4900 -DGSCSLTVNESTMSDE-GIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKF 4957
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLK 455
S+ ++ + ++ C P P + W +G LI++ R +N+ + L +K
Sbjct: 4958 ILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIK 5017
Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+ D GTY CVA++ +G + +D + +
Sbjct: 5018 NATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGV 5054
Score = 91.5 bits (217), Expect = 3e-18
Identities = 110/474 (23%), Positives = 186/474 (39%), Gaps = 49/474 (10%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
+P ++WYK + ++H G + A + D Y +N+ G S
Sbjct: 4258 APVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSS 4317
Query: 98 NATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
A V VL+ L+ + Q V L+ + G P+ + W KNGQ L D D
Sbjct: 4318 AALTVVKPNVLKIVDGLKDVDVEEPQ--PVELK-VKVEGIPKV-IKWYKNGQELKPDADG 4373
Query: 156 RM--HLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--- 208
+ G +L I ++++D G Y+ + N G S +H+K + P
Sbjct: 4374 FKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSV---VHVKSAKSSEPTSG 4430
Query: 209 -------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLR 258
+D + G +T QC + G+P P+V+W + + RV + +LR
Sbjct: 4431 ANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLR 4490
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARF 312
+ + +D G+Y A+N G+ ++ +TV + P + + G+ F
Sbjct: 4491 IRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEF 4550
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
G P+PT+ W + G P D+ + DG LTI D + D T+ C
Sbjct: 4551 NVKVRGLPKPTLQWFLNG-----IPIKFDDRITLDDMADGNYCLTIRDVREEDF-GTLKC 4604
Query: 373 SAVNYAGSSFV-------RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
A N G+ G + DD R PP ++ +P+ C P
Sbjct: 4605 IAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANP 4664
Query: 426 EPIIAWYFEGEALIQNHRRNVTN--DGTLVLK--DLDKSDSGTYTCVASSRHGK 475
+ W+ +G+ + + N DG +K ++SD G Y CVA + G+
Sbjct: 4665 TAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQ 4718
Score = 90.2 bits (214), Expect = 8e-18
Identities = 118/480 (24%), Positives = 194/480 (40%), Gaps = 35/480 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + + G + L
Sbjct: 3760 PEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEI 3816
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ ++ D Y +N G A S +A L V + E + +G VL+
Sbjct: 3817 PNAQL-DDTADYKVVVSNDAGDADS-SAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVET 3874
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAG- 187
+ E + W KNG+ + D DG N LVI DA DA Y+ + + G
Sbjct: 3875 NKKPKE--IKWYKNGKEIT-PSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGN 3931
Query: 188 TRESAIA-TLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242
T +S+ A T+K+ K P +I G ED V GS + + G P V W ++ G
Sbjct: 3932 TADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSP-KTVKWYKNGKELPGA 3990
Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP- 299
+++ +DD L + + ++ D G+Y E N G+ ++SG +TV +P L P
Sbjct: 3991 AAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-EPKITFLKPL 4049
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
++ G A F+ +P + W G I P ++ D L I
Sbjct: 4050 KDQSITEGENAEFSVETNTKPR-IVKWYKNGQE--IKP---NSRFIIEQKTDTKYQLVIK 4103
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
+ ++D+ +T N AG + +LTV I+ G +Q + + VF
Sbjct: 4104 NAVRDDA-DTYKIVLENTAGEAESSAQLTVKKAKAGLCKIV-KGLEDQVVAKGAKMVFEV 4161
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTN-DGT---LVLKDLDKSDSGTYTCVASSRHGK 475
PE + W + + + D T L++ D D+G YT + GK
Sbjct: 4162 KIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGK 4220
Score = 88.2 bits (209), Expect = 3e-17
Identities = 79/284 (27%), Positives = 116/284 (40%), Gaps = 10/284 (3%)
Query: 30 TLNCRA--GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
TL C+ G P+P ++WY G LV + I A G++ ++ HG G C A
Sbjct: 1939 TLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMK-IHGVTADMTGKIKCVA 1997
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + VA + EF +GDT+ L + G PEP V W NG+
Sbjct: 1998 YNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAV-LLGEPEPVVSWYVNGK 2056
Query: 148 TLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYL 204
L + ++H G + I+D +G+ C A N G T E+ + L P
Sbjct: 2057 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2116
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVI 263
+ +V A+TG+ V + GDP P + W + N L + D S N
Sbjct: 2117 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2176
Query: 264 LAD--EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
D GE C+AEN G VS + + Y + S + E
Sbjct: 2177 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAE 2220
Score = 86.6 bits (205), Expect = 9e-17
Identities = 98/460 (21%), Positives = 167/460 (36%), Gaps = 28/460 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P D V + G P P++ W G V + ++ G +
Sbjct: 1725 EVPKFTTNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTI 1784
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVL 127
+ AG CEATN G+ + R+ L V + + F E + +G+ ++
Sbjct: 1785 EIS-AVTPEQAGELSCEATNPVGS-KKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLM 1842
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNA 185
+ P+P + W K+G + DG ++ + G+L + + D GR A +
Sbjct: 1843 DAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESE 1902
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV--TFQCR--VGGDPLPDVLW----RR 237
G E + + + +P + +A + T +C+ + GDP P V W +
Sbjct: 1903 FGVAECSASLGVVKGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQL 1962
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
+ + + ++++ V G+ C A N G VS G L V P +
Sbjct: 1963 VCATEDTEISNANGVY--TMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEF 2020
Query: 298 SPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+ G+ + G PEP + W V G + K H+ G
Sbjct: 2021 ETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKK---LEESQNIKIHSEK---GTYT 2074
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+TI D D +VC A+N G + L V + PP SN +
Sbjct: 2075 VTIKDITC-DYSGQVVCEAINEYGKATSEATLLVLPRGE--PPDFLEWLSNVRARTGTKV 2131
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVL 454
V P+P + WY + ++ + VT+D T L
Sbjct: 2132 VHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTL 2171
Score = 86.2 bits (204), Expect = 1e-16
Identities = 80/296 (27%), Positives = 130/296 (43%), Gaps = 31/296 (10%)
Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAG-GLFFLRATHG 74
+PL+V + L G+P P + W+K + + ++H G G L
Sbjct: 2849 RPLEVR--EQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQA 2906
Query: 75 RVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R D GVY C+ATN G A++ N + + F + + QG L +
Sbjct: 2907 R-GEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAEL-VVRVE 2964
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGN----LVIQDARQTDAGRYQCIARNAAG 187
G PEP V W K+G + D H+++ G N LVI+D D G+Y C A N AG
Sbjct: 2965 GKPEPEVKWFKDGVPIAIDNQ---HVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAG 3021
Query: 188 TRESAIATLKI-----------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
++ + LKI +KP I ++ A G +V +C+V + P + +
Sbjct: 3022 -KDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFF 3080
Query: 237 RSAGGGNMPLG-RVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ + +++VL+DG+++L N D G Y CEA N G + + L +
Sbjct: 3081 KNDQPVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3136
Score = 81.0 bits (191), Expect = 5e-15
Identities = 123/534 (23%), Positives = 198/534 (37%), Gaps = 37/534 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP ++ + V + A C+ G+ P ++W+K G + D
Sbjct: 3377 APGFFKELSAIQVKETETAKFECKVSGT-KPDVKWFKDGTPLKEDKRVHFESTDDGTQRL 3435
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D G Y E +N G A S+ V + + QG ++L +
Sbjct: 3436 VIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLS-V 3494
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCI-ARNAAG 187
G P+ V W K +T+ +++ V L I+ A +D G Y+ + + ++
Sbjct: 3495 EVEGKPK-TVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFS 3553
Query: 188 TRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
SA T+ KI + P G D G+ + + + G P DV W ++ G
Sbjct: 3554 VESSATVTVTKAAEKISL-PSFKKGLADQSVPKGTPLVLEVEIEGKP-KDVKWYKN--GD 3609
Query: 243 NMPLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
+ G+V+ L +G RL + D GEYS A N G + + + V P I
Sbjct: 3610 EIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLV 3669
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
V+ G A F G P + W G I ++D DG L I +
Sbjct: 3670 PTTVKQGETATFNVKVKG-PVKGVKWYKNGKE--IPDAKTKDN------GDGSYSLEIPN 3720
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDD--DRPPPIITNGPSNQTLPIKSMAVF 417
D+ + V + N AG + LTV +DD D+ P I +G T+ A F
Sbjct: 3721 AQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATF 3779
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475
+ P + WY G+ I N + DG +L + + D+ Y V S+ G
Sbjct: 3780 N-VKVKGPVKQVKWYKNGKE-IPNAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGD 3837
Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
S AL V P I + + + +P + + W +N K
Sbjct: 3838 ADSSAALTVKL---PGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGK 3888
Score = 80.6 bits (190), Expect = 6e-15
Identities = 102/403 (25%), Positives = 167/403 (41%), Gaps = 33/403 (8%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA-GGL 66
G+AP + D + + ++ + P P I W K GV + SD H I+ G
Sbjct: 1820 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 1879
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQG 122
L ++ D G +A + +G A +A+L V + + F+ + +G
Sbjct: 1880 LKLSILQTKLE-DKGRITIKAESEFGVAEC-SASLGVVKGRPMAKPAFQSDIAPINLTEG 1937
Query: 123 DTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQC 180
DT LEC L G P P V W Q + D+ + +G + I G+ +C
Sbjct: 1938 DT--LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKC 1995
Query: 181 IARNAAGTRESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+A N AG S LK+ + P + T D + G ++ + + G+P P V W
Sbjct: 1996 VAYNKAG-EVSTEGPLKV-VAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2053
Query: 238 SAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---D 291
+ G +K+ + ++ + ++ G+ CEA N G ++ L V +
Sbjct: 2054 N-GKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGE 2112
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP ++V +G TG P+P++ W + N+ I+ + D Y T V D
Sbjct: 2113 PPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYIN-NKEIL----NSDLY--TIVTD 2165
Query: 352 GVT-VLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSD 392
T LTIN + + I+C A N AG S +T TSD
Sbjct: 2166 DKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTANMITYTSD 2208
Score = 75.8 bits (178), Expect = 2e-13
Identities = 99/334 (29%), Positives = 140/334 (41%), Gaps = 50/334 (14%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSI 60
D + G+AP PL + A+ T C G+P P+I+W K G+ + SD +
Sbjct: 5276 DSSIREGKAPGFTT-PLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKME 5334
Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-------EEFRLE 113
A G L + S+ G + C ATN +GTA S A L + R E E
Sbjct: 5335 AAADGTQRLILSDVTFLSE-GYFRCVATNEHGTA-STKAELVIEGDRTIGSRPLPEVNGE 5392
Query: 114 PES----------KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--- 160
PE S VV + G P P V W K+GQ ++ DG ++
Sbjct: 5393 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 5452
Query: 161 DGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---------PE 209
+ G +LVI +A D G Y A N G+ ++ +L I I+P I P
Sbjct: 5453 ERGIHHLVIVNASPDDEGEYSLEATNKLGSAKTE-GSLNI-IRPRHIADADERGGMPFPP 5510
Query: 210 DVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG----SLR 258
V Q + F C V G P P+V W + G +P GR+K+ G +L
Sbjct: 5511 GFVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHN-GKKIVPGGRIKIQSCGGGSHALI 5569
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ + L D GEY A+NS G+ S+S L V P
Sbjct: 5570 ILDTTLEDAGEYVATAKNSHGSASSSAVLDVTVP 5603
Score = 75.4 bits (177), Expect = 2e-13
Identities = 74/289 (25%), Positives = 114/289 (39%), Gaps = 23/289 (7%)
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DG--SLRLDNVILADEGEYSCE 273
SS +V G PLPD+ W + + D DG ++ +D V + D G Y+C
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 274 AENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
A N G S S + V PP+ + G+V F C G PEP + W
Sbjct: 623 ATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWL 682
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
V+ R + +DG T L I D +D+ N GS + +
Sbjct: 683 VDDQPL-------RPSHDFRLQYDGQTAKLEIRDAQPDDT-GVYTVKIQNEFGSIESKAE 734
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHR- 443
L V +D D+ + + + ++ T P P I W+ G+ L ++ +
Sbjct: 735 LFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKV 794
Query: 444 RNVTNDGTLVL--KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+ ++ DG +L KD+ + G TC S+R G G L V P P
Sbjct: 795 KFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP 843
Score = 74.5 bits (175), Expect = 4e-13
Identities = 119/491 (24%), Positives = 192/491 (39%), Gaps = 40/491 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFL 69
P II+ D V+ P L GSP ++WYK G + ++I ++
Sbjct: 3948 PKIIKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV 4006
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLE 128
V D G Y E N G+A N++ + V + L+P QS +G+ E
Sbjct: 4007 LEIPSSVVEDTGDYKVEVANEAGSA---NSSGKITVEPKITFLKPLKDQSITEGENA--E 4061
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARN 184
+ V W KNGQ + +SR + + LVI++A + DA Y+ + N
Sbjct: 4062 FSVETNTKPRIVKWYKNGQEI--KPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4119
Query: 185 AAGTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
AG ES+ K L + G ED V G+ + F+ ++ G+P DV W R A
Sbjct: 4120 TAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEP-EDVRWLRDANV 4178
Query: 242 GNMPLGRV-KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
+ + + +DD + RL + L D GEY+ E N G + V + P I
Sbjct: 4179 ISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRG 4238
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
++ + G+ F + P + W N I P A + L I
Sbjct: 4239 LENIEIPEGDDDVFKVEVSA-PVRQVKW--YKNDQEIKP---NSHLEAKKIGPKKYELAI 4292
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N +D + V + N AG LTV + I +G + +
Sbjct: 4293 NRAQLDDGADYKVVLS-NAAGDCDSSAALTVVKPNVLK---IVDGLKDVDVEEPQPVELK 4348
Query: 419 CTAICTPEPIIAWYFEGEAL------IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
P+ +I WY G+ L + + + + +L + KSD G Y V +
Sbjct: 4349 VKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGND 4407
Query: 473 HGKYVWSGALL 483
G+ V+SG+++
Sbjct: 4408 KGE-VYSGSVV 4417
Score = 72.5 bits (170), Expect = 2e-12
Identities = 87/393 (22%), Positives = 159/393 (40%), Gaps = 30/393 (7%)
Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
V+ +F + + ++ +G + V EC+ P + W K+G+ + R+ G
Sbjct: 2244 VMAPKFITKIKDTKAKKGHSAVFECVVP-DTKGVCCKWLKDGKEIELIARIRVQTRTGPE 2302
Query: 165 ------LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIK------PYLITGPED 210
LV+ + DAG+Y CI N AG T E+ + ++ K P I +D
Sbjct: 2303 GHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQD 2362
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
+T V +C+V G+P P V W V+ ++ + + + L+ +G+
Sbjct: 2363 KTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTITSSELSHQGK 2422
Query: 270 YSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
Y+C AEN+ G +LTV + P + + G +C+ G P+P + +
Sbjct: 2423 YTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYS 2482
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVT--VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
T + ++ A T + I+ K D + A N G++ K
Sbjct: 2483 FSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDI-VSYKAIATNSIGTATSTSK 2541
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NH-- 442
+T + P+ G ++ K + P + W+ + + + + NH
Sbjct: 2542 ITTKVE----APVFEQGLKKTSVKEKEEIKME-VKVGGSAPDVEWFKDDKPVSEDGNHEM 2596
Query: 443 RRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
++N T TLV+K +D+G YT AS+ G
Sbjct: 2597 KKNPETGVFTLVVKQAATTDAGKYTAKASNPAG 2629
Score = 72.5 bits (170), Expect = 2e-12
Identities = 119/493 (24%), Positives = 193/493 (39%), Gaps = 42/493 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + G + L
Sbjct: 3662 PEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD--NGDGSYSLEI 3718
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSA------QGDT 124
+ +V DA Y +N G A S +A L V + + + +++PE QG+T
Sbjct: 3719 PNAQVE-DAADYKVVVSNDAGDADS-SAALTVKLADDGKDKVKPEIVSGLIPTTVKQGET 3776
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ +G P V W KNG+ + + ++ + +L I +A+ D Y+ + N
Sbjct: 3777 ATFN-VKVKG-PVKQVKWYKNGKEIP-NAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSN 3833
Query: 185 AAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
AG +S+ A T+K+ ++ G ED G Q P ++ W ++ G
Sbjct: 3834 DAGDADSSAALTVKLP-GIAIVKGLEDAEVPKGKKAVLQVETNKKP-KEIKWYKN-GKEI 3890
Query: 244 MPLGRVKVLDDGSLRLDNVILA----DEGEYSCEAENSVG-AVSASGYLTVYDP---PSI 295
P + + DG + VI D EY + G +S LTV P P I
Sbjct: 3891 TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKI 3950
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
V G+ + +G P+ T+ W G PG + + D V
Sbjct: 3951 IKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKE---LPGAAAKTIKIQKIDDNKYV 4006
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L I + D+ + V N AGS+ GK+TV P +Q++ A
Sbjct: 4007 LEIPSSVVEDTGDYKV-EVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGENA 4060
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
F P I+ WY G+ + N R + LV+K+ + D+ TY V +
Sbjct: 4061 EFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4119
Query: 472 RHGKYVWSGALLV 484
G+ S L V
Sbjct: 4120 TAGEAESSAQLTV 4132
Score = 70.1 bits (164), Expect = 9e-12
Identities = 133/588 (22%), Positives = 217/588 (36%), Gaps = 54/588 (9%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
S AP ++ D TV + A G+P+P + W+ G + + + A
Sbjct: 942 SRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHD 1001
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-------SKQSA 120
+ AG C A N+ G ++ + VL E + +P K
Sbjct: 1002 HKLTIDSAQY--AGTVLCRAENAVGRFETK---ARLVVLAPEKQKKPPKFVEILVDKTET 1056
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179
+TVV E + G P+P V W G+ L + DG + I++ + DAG +
Sbjct: 1057 VDNTVVFE-VRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115
Query: 180 CIARNAAGTRESAIATLKIHIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
+A N+ G+ E+ A L + KP+ P + + GS F G PLP W
Sbjct: 1116 AVATNSEGSDETK-AKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWS 1174
Query: 237 RSA-----GGGNMPLGRVKVLDDGS--LRLDNVILADEGEY---SCEAENSVGAVSASGY 286
+ G + R + DG+ L +D E + S AEN++GA
Sbjct: 1175 VNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQ 1234
Query: 287 LTV--YDPPSINLSPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
LT+ PP+ L+ + V ++A F E W ++G G++
Sbjct: 1235 LTIEPKKPPAPKLTRDLKLQTVNKTDLAHFEVVVEHATE--CKWFLDGKEITTAQGVTVS 1292
Query: 343 KYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIIT 401
K D DT S T+ A N AGS + +L V + + P T
Sbjct: 1293 K------DDQFEFRCSIDTTMFGS-GTVSVVASNAAGSVETKTELKVLETPKETKKPEFT 1345
Query: 402 NGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-----NDGTLVLKD 456
+ + + + I P+ WY G L+++ + VT N +L++
Sbjct: 1346 D--KLRDMEVTKGDTVQMDVIALHSPLYKWYQNGN-LLEDGKNGVTIKNEENKSSLIIP- 1401
Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT 516
+ DSG T AS+ G S L V+ P I V ++ T ++
Sbjct: 1402 -NAQDSGKITVEASNEVGSSESSAQLTVNPPSTTPIVVDGPKSV-TIKETETAEFKATIS 1459
Query: 517 D-TSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
+ T+ W+ N KI S ++ TL +N G V +
Sbjct: 1460 GFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKISNAKIEQTGTVKV 1507
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 15/207 (7%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG---QTLLFDGDSRMHLVDGGN--LVIQD 169
E + A+ DT+ + L G P+P++ WK G T +++ G L I
Sbjct: 5777 EKRYCAENDTLTI-VLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITG 5835
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
+ + G+YQC A+N G + I + + +P I + + + RV G+P
Sbjct: 5836 FSKENVGQYQCFAKNDYGDAQQNIM-VDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEP 5894
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P++ W + + R+K + DG SL +++ + D G YSC A N G + S
Sbjct: 5895 FPELKWMKE-WRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 5953
Query: 286 YLTVY---DPPSINLSPNSVNVESGNV 309
+TV D + L V +ES V
Sbjct: 5954 TVTVEAEGDYNDVELPRRRVTIESRRV 5980
Score = 61.7 bits (143), Expect = 3e-09
Identities = 66/257 (25%), Positives = 93/257 (36%), Gaps = 16/257 (6%)
Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
+VG ++S T P S V A C G P P + W+ EG
Sbjct: 3161 TVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEV--- 3217
Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD--- 393
MS + A DG LT ++ + D+ C A N GS++ G + VT +
Sbjct: 3218 -EMSA-RVRAEHKDDGTLTLTFDNVTQADA-GEYRCEAENEYGSAWTEGPIIVTLEGAPK 3274
Query: 394 -DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DG 450
D P + + AV P+P + WY GE L + R + N DG
Sbjct: 3275 IDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDG 3334
Query: 451 T--LVLKDLDKSDSGTYTCVASSRHGKYVWSG-ALLVDSPINPNIHFFRAADVSSLPGPP 507
T L + + D Y C AS+ G VWS L V P FF+ +
Sbjct: 3335 TQRLTVTNAKLDDMDEYRCEASNEFGD-VWSDVTLTVKEPAQVAPGFFKELSAIQVKETE 3393
Query: 508 TKPITHNVTDTSVTLSW 524
T V+ T + W
Sbjct: 3394 TAKFECKVSGTKPDVKW 3410
Score = 60.9 bits (141), Expect = 5e-09
Identities = 54/215 (25%), Positives = 86/215 (40%), Gaps = 25/215 (11%)
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
T +DD PI T + L A+F C +P P + W F+G+ L N R +
Sbjct: 6878 TKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIE 6937
Query: 448 NDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLP 504
D L+L D G Y C A + +G S L+ + + S P
Sbjct: 6938 QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI-------------SGETPSRP 6984
Query: 505 GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564
G P ++ +DT + + W G + + G + R ++G N + W+ ++
Sbjct: 6985 GRPEAELS---SDTEIFIQWEAPE--GPTYLEGITYRLEYR--VAGPND--HGDPWITVS 7035
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
++ +VK L P Y F V +N GL PS
Sbjct: 7036 EKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPS 7070
Score = 60.5 bits (140), Expect = 7e-09
Identities = 89/376 (23%), Positives = 149/376 (39%), Gaps = 27/376 (7%)
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
D +G +A NAAG+ E+ LK+ P PE VT V D
Sbjct: 1304 DTTMFGSGTVSVVASNAAGSVETK-TELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMD 1362
Query: 229 --PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVGAVSA 283
L L++ G + G+ V ++I+ D G+ + EA N VG+ +
Sbjct: 1363 VIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSES 1422
Query: 284 SGYLTVYDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
S LTV P P + P SV ++ A F T +G P PT+ W++ N I+
Sbjct: 1423 SAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTI--NEKIV----E 1476
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP--PP 398
+ T + V L I++ K + T+ +A N AG + L V + P
Sbjct: 1477 ESRTITTIKTEDVYTLKISNA-KIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 1535
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGT--LVL 454
+T+ +++ P++ +P ++W G+ L ++ V + DGT + +
Sbjct: 1536 QLTDKVADEGEPLRWNLELDGP---SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTI 1592
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514
+ SGT T A + G+ S + V+ N F +A + +
Sbjct: 1593 AEAKPEMSGTLTAKAKNAAGECETSAKVTVNGG-NKKPEFVQAPQNHETTLEESVKFSAI 1651
Query: 515 VTDTSV-TLSWSQNNK 529
VT + ++W NNK
Sbjct: 1652 VTGKPMPNVTWYLNNK 1667
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 12/171 (7%)
Query: 24 ARHQPATLNCRAGGSPSPAIRW-YKG-GVLVVSDTHR-SILPAGGLFFLRATHGRVHSDA 80
A + T+ G P P I+W ++G + S T + + GG A G +
Sbjct: 5782 AENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENV 5841
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N YG A+ +N + +A R F ++P ++ + + G P P +
Sbjct: 5842 GQYQCFAKNDYGDAQ-QNIMVDLAT-RPNF-IQPLVNKTFSSAQPMRMDVRVDGEPFPEL 5898
Query: 141 YWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG 187
W K + ++ SR+ V G +L+I D D+G Y C+A N AG
Sbjct: 5899 KWMKEWRPIV--ESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAG 5947
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + DV + ++QPA C SP+P + W G ++ S+ +I + L
Sbjct: 6887 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 6946
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARS 96
H + D G Y C A N YGT +S
Sbjct: 6947 LNHAAPY-DLGEYVCTAINEYGTDKS 6971
Score = 41.1 bits (92), Expect = 0.005
Identities = 40/187 (21%), Positives = 67/187 (35%), Gaps = 12/187 (6%)
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT-AVFDGVTVLTINDTDKNDSRN 368
A+ TG P P + W + + + D+ H + DG +TI+ D+
Sbjct: 565 AKMCLKVTGYPLPDITWYKDDVQ------LHEDERHTFYSDEDGFFAMTIDPVQVTDT-G 617
Query: 369 TIVCSAVNYAGSSFVRGKLTVTS-DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
C A N G + V + + PP ++ + F C PEP
Sbjct: 618 RYTCMATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEP 677
Query: 428 IIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
+ W + + L +H + DG L ++D D+G YT + G L V
Sbjct: 678 ELVWLVDDQPLRPSHDFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFV 737
Query: 485 DSPINPN 491
+ + N
Sbjct: 738 QADPDKN 744
Score = 39.9 bits (89), Expect = 0.011
Identities = 21/83 (25%), Positives = 36/83 (43%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ ++ T + QP ++ R G P P ++W K +V + + G
Sbjct: 5867 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 5926
Query: 72 THGRVHSDAGVYWCEATNSYGTA 94
+ + D+G+Y C A N G A
Sbjct: 5927 INDPMWRDSGIYSCVAVNDAGQA 5949
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P P + W E ++++ R DG +L++ D DSG Y+CVA + G+ S
Sbjct: 5894 PFPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 5953
Query: 481 ALLVDS 486
+ V++
Sbjct: 5954 TVTVEA 5959
Score = 33.5 bits (73), Expect = 0.93
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 4/88 (4%)
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILAD 266
DV + F+C V P P V W G RV + D + L L++ D
Sbjct: 6896 DVYLRKNQPAIFECAVSASPAPKVTW-DFQGKILESNDRVTIEQDNNVARLILNHAAPYD 6954
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPS 294
GEY C A N G +S L + PS
Sbjct: 6955 LGEYVCTAINEYGTDKSSCRLISGETPS 6982
Score = 33.5 bits (73), Expect = 0.93
Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIA 182
+ EC SP P V W G+ L + + R+ + N L++ A D G Y C A
Sbjct: 6906 IFECAVS-ASPAPKVTWDFQGKIL--ESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTA 6962
Query: 183 RNAAGTRESA 192
N GT +S+
Sbjct: 6963 INEYGTDKSS 6972
>AF003131-1|AAP68958.1| 8081|Caenorhabditis elegans Uncoordinated
protein 89, isoform b protein.
Length = 8081
Score = 146 bits (354), Expect = 8e-35
Identities = 178/689 (25%), Positives = 281/689 (40%), Gaps = 110/689 (15%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAG 64
VT+ + P + DV QP L C+ SP P + WYK G +V SD + L
Sbjct: 5695 VTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPD 5754
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLREEFR--- 111
G+ L V+ D G+Y ATN GTA+ R++ + R+ F
Sbjct: 5755 GVATLLIP-SCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANK 5813
Query: 112 ----LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-- 164
+EP E+ + + + L C G P+P + W K+G+ + G R+ L++ +
Sbjct: 5814 APKLMEPLENIRIPEKQSFRLRC-KFSGDPKPTIKWFKDGERVFPYG--RLQLIESPDGV 5870
Query: 165 --LVIQDARQTDAGRYQCIARNAAGTRESA--IATLKIHIKPYLI------------TGP 208
LV+ A + DAG Y+C+A N G+ ++ + ++ KP I T P
Sbjct: 5871 CELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTP 5930
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL--DNVI 263
+ A+ G SVTF+C G+P P + W + G ++K+ DG+ RL +V
Sbjct: 5931 LTIRRAKPGDSVTFECLPFGNPFPSIKWLKD-GLELFSDEKIKMEAAADGTQRLILSDVT 5989
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDP--------PSINLSPN-----------SVNV 304
EG + C A N G S L + P +N P ++++
Sbjct: 5990 FLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMSI 6049
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
GNV ATG P PT+ W +G + I+ G + T G+ L I + +
Sbjct: 6050 HEGNVVEMIVCATGIPTPTVKWYKDG-QEIVGDGPDGKRVIFTDE-RGIHHLVIVNASPD 6107
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLT------VTSDDDRP----PPIITNGPSNQTLPIKSM 414
D A N GS+ G L + D+R PP N+ +
Sbjct: 6108 D-EGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMP 6166
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVAS 470
+F C + P P + W+ G+ ++ R + + G L++ D D+G Y A
Sbjct: 6167 TIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATAK 6226
Query: 471 SRHGKYVWSGALLVDSPINPNIHF---------------FRAADVSSLPGPPTK-PITHN 514
+ HG S L V P +I F F+ + +SLP PP + P
Sbjct: 6227 NSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKKLNTASLPTPPDRGPFIKE 6286
Query: 515 VTDTSVTLSWSQNNKIGSS-SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
VT +TLSW + + Y +E+ RE + W ++ + +
Sbjct: 6287 VTGHYLTLSWIPTKRAPPRYPQVTYVIEI--REL--------PEKQWSLLEYNIPEPVCK 6336
Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVS 602
V++L G +Y F VR EN +G+S PSP S
Sbjct: 6337 VRNLELGKSYQFRVRAENIYGISDPSPAS 6365
Score = 140 bits (339), Expect = 5e-33
Identities = 139/499 (27%), Positives = 208/499 (41%), Gaps = 62/499 (12%)
Query: 28 PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-PAGGLFFLRATHGRVHSDAGVYWCE 86
P + C +P+ + W+K G + H I G ++ SD GVY C
Sbjct: 5293 PMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFE-ESDIGVYMCV 5351
Query: 87 ATNSYGTARSRNATLHVAVL-------REEF--RLEP--ESKQSAQGDTVVLECLPPRGS 135
A N G A ++ AT V +L R E+ ++ P E K G + L C
Sbjct: 5352 AVNELGQAETQ-ATYQVEILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSC-KVDAI 5409
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGT-RESA 192
P +V W K+G L D + + + G L I D+ + D G Y+C+A NA GT S
Sbjct: 5410 PRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSC 5469
Query: 193 IATLKI---HIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGN 243
+K+ +K P+ G D+ A G S T +C V GDP P++ W R+ N
Sbjct: 5470 SVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRN 5529
Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY----------- 290
P ++ DG SL ++ ++DEG Y CEAEN+ G V
Sbjct: 5530 GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKM 5589
Query: 291 ---DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
PP L + ++V GNV C TG P P++ WS +G I SR ++ +
Sbjct: 5590 DEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLI---EDSRFEW-SN 5645
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSN 406
GV L I + +D T C A N GS+ K V DD ++T + P
Sbjct: 5646 EASKGVYQLRIKNATVHD-EGTYRCVATNENGSATT--KSFVRMDDGLGSGVVTASQPPR 5702
Query: 407 QTLPIKSMAV-------FPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDG--TLVLK 455
TL + + C +P P + WY +G + + R + + DG TL++
Sbjct: 5703 FTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIP 5762
Query: 456 DLDKSDSGTYTCVASSRHG 474
D G Y +A++ G
Sbjct: 5763 SCVYDDDGIYRVIATNPSG 5781
Score = 139 bits (336), Expect = 1e-32
Identities = 142/521 (27%), Positives = 221/521 (42%), Gaps = 71/521 (13%)
Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I PL D TV QP L+C+ P ++ WYK G+ + +D+ SI A +
Sbjct: 5385 INPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIN 5444
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---------QSAQGDT 124
D G Y C ATN++GT + + +++V V ++E + E E + +GD+
Sbjct: 5445 DSTEEDIGAYRCVATNAHGTINT-SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDS 5503
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGG-NLVIQDARQTDAGRYQCI 181
L+C G P P + W +NGQ LL +G + DG +L + ++ +D G Y+C
Sbjct: 5504 FTLKC-AVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561
Query: 182 ARNAAG-TRESAIATLKIHI----KPYLITGP--------EDVVAQTGSSVTFQCRVGGD 228
A NA G + A A +++ + KP + G D+ G+ + +C+V G
Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGL 5621
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVS- 282
P P V W + GG + R + ++ S LR+ N + DEG Y C A N G+ +
Sbjct: 5622 PNPSVKWSKD-GGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATT 5680
Query: 283 ----------ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
SG +T PP L V G + C P P M W +G
Sbjct: 5681 KSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG-- 5738
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--- 389
I+ P D+ + DGV L I +D V A N +G++ +G TV
Sbjct: 5739 AIVTPS---DRIQISLSPDGVATLLIPSCVYDDDGIYRVI-ATNPSGTAQDKGTATVKKL 5794
Query: 390 --------TSD----DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
++D D P + N +P K C P+P I W+ +GE
Sbjct: 5795 PRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGER 5854
Query: 438 LIQNHRRNV--TNDGT--LVLKDLDKSDSGTYTCVASSRHG 474
+ R + + DG LV+ + D+G Y CVA + +G
Sbjct: 5855 VFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYG 5895
Score = 136 bits (328), Expect = 1e-31
Identities = 127/499 (25%), Positives = 210/499 (42%), Gaps = 32/499 (6%)
Query: 7 TSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PA 63
T EAP + EQ L T V + + + GGS +P + W+K V D + + P
Sbjct: 3184 TKVEAP-VFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDDKPVSEDGNHEMKKNPE 3241
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQG 122
G+F L +DAG Y +A+N GTA S A + ++ + F E + +
Sbjct: 3242 TGVFTLVVKQAAT-TDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKIN 3300
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQ 179
+T L + +G P+P+V W K+GQ + D + V+G ++ I+DAR D+G+Y
Sbjct: 3301 ETATLS-VTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYA 3359
Query: 180 CIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
C A N AG E+ A +K + P + + + S T +V G P P V W +
Sbjct: 3360 CRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFK 3419
Query: 238 SAGGGNMP----LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYD- 291
++ + + + SL +++ D G YSC A N G A++ + + + D
Sbjct: 3420 DDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS 3479
Query: 292 -PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
PP + V T G P P + W + ++ I + A
Sbjct: 3480 IPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEW-FKDDKPI---NIDNSHIFAKDEG 3535
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G LTI + + C A N AG + + V + + P + G +
Sbjct: 3536 SGHHTLTIKQA-RGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP--LFVQGLKPYEVE 3592
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTY 465
A PEP + W+ +G + +++ + G TLV+KD + +D G Y
Sbjct: 3593 QGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKY 3652
Query: 466 TCVASSRHGKYVWSGALLV 484
TC A+++ GK G L +
Sbjct: 3653 TCQATNKAGKDETVGELKI 3671
Score = 135 bits (327), Expect = 2e-31
Identities = 129/483 (26%), Positives = 199/483 (41%), Gaps = 34/483 (7%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + + G P P I WYK V + D + FF +D G Y C AT
Sbjct: 565 AKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMAT 624
Query: 89 NSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
N YG A S +A V + +E F + K+ +GD + EC G PEP + W
Sbjct: 625 NEYGQA-STSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFEC-EVEGWPEPELVWL 682
Query: 144 KNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL----- 196
+ Q L D R+ DG L I+DA+ D G Y +N G+ ES
Sbjct: 683 VDDQPLRPSHDFRLQ-YDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADP 741
Query: 197 -KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDD 254
K H+ P E V G V F+ + GDP P+++W + G +VK + +D
Sbjct: 742 DKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFIN-GKPLSESEKVKFISED 800
Query: 255 G--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNV 309
G L + +V +G +C+ N +G+ S G L V PP+ N V+ +
Sbjct: 801 GICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKST 860
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
F +G PEPT+ +++ G + ++ DG ++I +T +
Sbjct: 861 VVFEVDVSGWPEPTLTFTLCGKEL-----KNGEEGVEIVGHDGFYRISIPNTSMDKHDGE 915
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDD--RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
IV A N G++ R +LTV +++ R P +QT+ AVF T P P
Sbjct: 916 IVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNP 975
Query: 428 IIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
+ W+ G + Q + N + D +GT C A + G++ L+V
Sbjct: 976 EVTWFINGHKMDQGSPGVKIEAHNHDHKLTID-SAQYAGTVLCRAENAVGRFETKARLVV 1034
Query: 485 DSP 487
+P
Sbjct: 1035 LAP 1037
Score = 126 bits (303), Expect = 1e-28
Identities = 139/544 (25%), Positives = 222/544 (40%), Gaps = 78/544 (14%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GE P+ + +D+ R TL C G P P I+WY+ G L+ + I +
Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC 5543
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREE-----------FRLEPE 115
+ SD G+Y CEA N++G A+++ AT HV A+ + E F LE
Sbjct: 5544 SLTVNESTMSDEGIYRCEAENAHGKAKTQ-ATAHVQMALGKTEKPKMDEGKPPKFILELS 5602
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-----LVIQDA 170
+ G+ + LEC G P P+V W K+G L+ DSR + + L I++A
Sbjct: 5603 DMSVSLGNVIDLEC-KVTGLPNPSVKWSKDGGPLI--EDSRFEWSNEASKGVYQLRIKNA 5659
Query: 171 RQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPE---------DVVAQTGSSVT 220
D G Y+C+A N G+ + + + + ++T + DV G +
Sbjct: 5660 TVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLK 5719
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDG--SLRLDNVILADEGEYSCEAEN 276
+C+V PLP+++W + G P R+++ DG +L + + + D+G Y A N
Sbjct: 5720 LECKVDASPLPEMVWYKD-GAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATN 5778
Query: 277 SVGAVSASGYLTVYDPP--------------SINLSP------NSVNVESGNVARFTCTA 316
G G TV P N +P ++ + R C
Sbjct: 5779 PSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKF 5838
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
+G P+PT+ W +G R +FP + DGV L ++ + D+ C A N
Sbjct: 5839 SGDPKPTIKWFKDGER--VFP---YGRLQLIESPDGVCELVVDSATRQDA-GGYRCVAEN 5892
Query: 377 YAGSSFVRGKLTVTSDDDRPPPI---ITNGPS-NQTLPIK-------SMAVFPCTAICTP 425
GS+ + V D +P I I G + T P+ F C P
Sbjct: 5893 TYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNP 5952
Query: 426 EPIIAWYFEGEALIQNH--RRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P I W +G L + + DGT L+L D+ G + CVA++ HG
Sbjct: 5953 FPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 6012
Query: 482 LLVD 485
L+++
Sbjct: 6013 LVIE 6016
Score = 124 bits (298), Expect = 5e-28
Identities = 126/498 (25%), Positives = 203/498 (40%), Gaps = 46/498 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLF 67
E P + + + V ++ ATL+ G P P++ W K G V +D+ I + G +
Sbjct: 3284 EKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSY 3343
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEF--RLEPESKQSAQGDT 124
+ R+ D+G Y C ATN G A++ N + ++ EF +L P + + T
Sbjct: 3344 SITIKDARLE-DSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTT 3402
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCI 181
+ ++ + G+PEP+V W K+ + D + V +L I DARQ D G Y C
Sbjct: 3403 LSVKVV---GTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCR 3459
Query: 182 ARNAAG--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
ARN AG + ++ I P + + ++ + V G P+P+V W +
Sbjct: 3460 ARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDD 3519
Query: 240 GGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
N+ + D+GS L + D G Y+C+A N G + + V +
Sbjct: 3520 KPINIDNSHIFAKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEA 3579
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV--F 350
P VE G A G+PEP + W +G I D H
Sbjct: 3580 PLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAI------DNQHVIEKKGE 3633
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--------TSDDDRPPPIITN 402
+G L I DT+ D C A N AG G+L + T+++ +P +
Sbjct: 3634 NGSHTLVIKDTNNADF-GKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKP---LFI 3689
Query: 403 GPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR-NVTNDGT--LVLKDL 457
P +T ++ V C P I ++ + + I H + V DG L +++
Sbjct: 3690 EPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNA 3749
Query: 458 DKSDSGTYTCVASSRHGK 475
K D G Y C A + GK
Sbjct: 3750 KKEDVGAYRCEAVNVAGK 3767
Score = 112 bits (270), Expect = 1e-24
Identities = 127/493 (25%), Positives = 204/493 (41%), Gaps = 39/493 (7%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGG 65
T AP +E TV Q A L C+ G P P I+W K G V +S R+ G
Sbjct: 3812 TGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDG 3871
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ---- 121
L +DAG Y CEA N YG+A + + L +++ E+ Q
Sbjct: 3872 TLTL-TFDNVTQADAGEYRCEAENEYGSAWTEGPI--IVTLEGAPKIDGEAPDFLQPVKP 3928
Query: 122 -----GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTD 174
G+T VLE G P+P+V W KNG+ L ++ +D G L + +A+ D
Sbjct: 3929 AVVTVGETAVLEG-KISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAKLDD 3987
Query: 175 AGRYQCIARNAAGTRESAIA-TLK--IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
Y+C A N G S + T+K + P + + + F+C+V G P
Sbjct: 3988 MDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECKVSGTK-P 4046
Query: 232 DVLWRRSAGGGNMPLGRV--KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYL 287
DV W + G RV + DDG+ RL ++ D+G Y E N G ++ L
Sbjct: 4047 DVKWFKD-GTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSKVPL 4105
Query: 288 TVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
TV ++ + VNV G + G+P+ T+ W +G T+ S
Sbjct: 4106 TVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPK-TVKW-YKGTETV----TSSQTTK 4159
Query: 346 ATAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDR-PPPIITNG 403
V + L I + +D+ +V S +++ S +TVT ++ P G
Sbjct: 4160 IVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVES--SATVTVTKAAEKISLPSFKKG 4217
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDS 462
++Q++P + V P+ + WY G+ + ++ N L + D + D
Sbjct: 4218 LADQSVPKGTPLVLEVEIEGKPKD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQEKDV 4276
Query: 463 GTYTCVASSRHGK 475
G Y+ A++ G+
Sbjct: 4277 GEYSVTAANEAGE 4289
Score = 107 bits (257), Expect = 5e-23
Identities = 120/492 (24%), Positives = 196/492 (39%), Gaps = 35/492 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P +++ P VT+ + A G P+P ++W +V + + ++ L+
Sbjct: 2075 PIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKI 2134
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLEC 129
++ ++ G A NS G S+ A L V V +F+ + K + +G+ +
Sbjct: 2135 SNAKI-EQTGTVKVTAQNSAG-QDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNL 2192
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNA 185
SP V W NGQ L + +VD G ++ I +A+ +G A+NA
Sbjct: 2193 ELDGPSPGTEVSWLLNGQPL--TKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTAKAKNA 2250
Query: 186 AGTRE-SAIATLK-IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
AG E SA T+ + KP + P++ SV F V G P+P+V W ++
Sbjct: 2251 AGECETSAKVTVNGGNKKPEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLI 2310
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPSIN 296
+ + V S+R+ ++ G EAEN G V A+ L V + P
Sbjct: 2311 QSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFT 2370
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTV 355
+ + V+ G +FT G PEP++ W++ G P ++ DK DG
Sbjct: 2371 TNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDK-------DGEHT 2423
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I+ + + C A N GS +L V D P ++ + +
Sbjct: 2424 IEISAVTP-EQAGELSCEATNPVGSKKRDVQLAVKKVGD--APTFAKNLEDRLITEGELT 2480
Query: 416 VFPCTA-ICTPEPIIAWYFEG-EALIQNHRRNV-TNDGTLVLKDLDK--SDSGTYTCVAS 470
+ I P+P I W +G E H + V DG+L L L D G T A
Sbjct: 2481 LMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAE 2540
Query: 471 SRHGKYVWSGAL 482
S G S +L
Sbjct: 2541 SEFGVAECSASL 2552
Score = 106 bits (255), Expect = 8e-23
Identities = 116/490 (23%), Positives = 195/490 (39%), Gaps = 39/490 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP I D T + L C+ G P P + W + ++ ++ G+ +
Sbjct: 2992 KAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQES-ITVESVEGVERV 3050
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
T + S G Y C A N+ GT+++ A L V F E ++K+ + G+ +VL C
Sbjct: 3051 TITSSEL-SHQGKYTCIAENTEGTSKT-EAFLTVQGEAPVFTKELQNKELSIGEKLVLSC 3108
Query: 130 LPPRGSPEPNVYWKKNGQTLLFD----GDSRMHLV-DGGN----LVIQDARQTDAGRYQC 180
+GSP+P+V + +T + SR+ + D N +VI + D Y+
Sbjct: 3109 -SVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKA 3167
Query: 181 IARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS- 238
IA N+ GT S + T K+ P G + + + + +VGG PDV W +
Sbjct: 3168 IATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDD 3225
Query: 239 ---AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
+ GN + + +L + D G+Y+ +A N G +S V +
Sbjct: 3226 KPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEK 3285
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD- 351
P+ + V+ A + T G P+P++ W +G + D H A +
Sbjct: 3286 PTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQ------PVQTDSSHVIAKVEG 3339
Query: 352 -GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G +TI D DS C A N AG + V + PP S +
Sbjct: 3340 SGSYSITIKDARLEDS-GKYACRATNPAGEAKTEANFAVVK--NLVPPEFVEKLSPLEVK 3396
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEAL-IQN----HRRNVTNDGTLVLKDLDKSDSGTY 465
K + TPEP + W+ + + I N ++ +L + D + D G Y
Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIY 3456
Query: 466 TCVASSRHGK 475
+C A + G+
Sbjct: 3457 SCRARNEAGE 3466
Score = 104 bits (249), Expect = 4e-22
Identities = 126/505 (24%), Positives = 191/505 (37%), Gaps = 36/505 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GEAP ++ + ++ + L+C GSP P + +Y +T + +
Sbjct: 3084 GEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEH 3143
Query: 69 LRA-THGRV------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
+ TH R+ D Y ATNS GTA S T + E E K+++
Sbjct: 3144 DQTNTHWRMVISQITKEDIVSYKAIATNSIGTATS---TSKITTKVEAPVFEQGLKKTSV 3200
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGG--NLVIQDARQTDAGRY 178
+ ++ G P+V W K+ + + DG+ M + G LV++ A TDAG+Y
Sbjct: 3201 KEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKY 3260
Query: 179 QCIARNAAGTRES---AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
A N AGT ES A T + KP + + + T V G P P V W
Sbjct: 3261 TAKASNPAGTAESSAEAEVTQSLE-KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEW 3319
Query: 236 RRSAGGGNMPLGRV--KVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
+ V KV G S+ + + L D G+Y+C A N G V
Sbjct: 3320 LKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVK 3379
Query: 292 ---PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
PP + + V+ + G PEP++ W + I K A
Sbjct: 3380 NLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVG 3439
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
F LTIND + D C A N AG + + D PP T
Sbjct: 3440 SFS----LTINDARQGDV-GIYSCRARNEAGEALTTANFGIIRDS--IPPEFTQKLRPLE 3492
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG----TLVLKDLDKSDSG 463
+ + T I TP P + W+ + + + I N ++G TL +K D G
Sbjct: 3493 VREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQARGEDVG 3552
Query: 464 TYTCVASSRHGKYVWSGALLVDSPI 488
YTC A++ G+ + + V I
Sbjct: 3553 VYTCKATNEAGEAKTTANMAVQEEI 3577
Score = 102 bits (245), Expect = 1e-21
Identities = 117/404 (28%), Positives = 165/404 (40%), Gaps = 33/404 (8%)
Query: 11 APYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
AP +PL D TV G P P + + G L + I+ G +
Sbjct: 842 APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYR 901
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP------ESKQSAQG 122
+ + + G +A N +GTA SR A L V EE R P E + G
Sbjct: 902 ISIPNTSMDKHDGEIVAKAQNEHGTAESR-ARLTVEQEEEESRSAPTFLKDIEDQTVKTG 960
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRY 178
+ V E RG+P P V W NG + D S ++ N L I A+ AG
Sbjct: 961 EFAVFETTV-RGNPNPEVTWFINGHKM--DQGSPGVKIEAHNHDHKLTIDSAQY--AGTV 1015
Query: 179 QCIARNAAGTRES-----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
C A NA G E+ +A K P + D ++V F+ RV G+P P V
Sbjct: 1016 LCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTV 1075
Query: 234 LWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVY 290
W G RV++ + DGS+++ N+ + D GE A NS G+ LTV
Sbjct: 1076 TWYLK-GEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134
Query: 291 DPP---SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P +L P S+ VE G+ A F+ A G P PT WSV G + +R +
Sbjct: 1135 KKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDES 1194
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAV--NYAGSSFVRGKLTV 389
V DG ++LTI+ N + S V N G+ +LT+
Sbjct: 1195 TV-DGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTI 1237
Score = 99.5 bits (237), Expect = 1e-20
Identities = 125/500 (25%), Positives = 188/500 (37%), Gaps = 54/500 (10%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA-GGLFFLRATHGRVHS 78
D V TL C G P P + W K GV++ D ++ A G LR + S
Sbjct: 5079 DTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSAK-KS 5137
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPR 133
D G Y A N G+A S + + V E+ F + ++ + GD + R
Sbjct: 5138 DIGQYRVTAKNEAGSATS-DCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEFN-VKVR 5195
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
G P+P + W NG + FD + + GN L I+D R+ D G +CIA+N GT E+
Sbjct: 5196 GLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDET 5255
Query: 192 AIATLK-----------IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
+ + P D G + +C V +P +V W +
Sbjct: 5256 VCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGK 5315
Query: 241 G-GNMPLGRVKVLDDGSLRLDNVIL--ADEGEYSCEAENSVG--AVSASGYLTVYD---- 291
+ ++ DG+ R+ + +D G Y C A N +G A+ + + +
Sbjct: 5316 KIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEE 5375
Query: 292 ------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
P IN V G R +C P ++ W +G P + +
Sbjct: 5376 EKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG-----LPLRADSRTS 5430
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG----SSFVRGKLTVTS-DDDRPPPII 400
DG L IND+ + D C A N G S V K+ + P
Sbjct: 5431 IQYEEDGTATLAINDSTEEDI-GAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFF 5489
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV---TNDG--TLVLK 455
T G + C P P I WY G+ L++N R V + DG +L +
Sbjct: 5490 TKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVN 5548
Query: 456 DLDKSDSGTYTCVASSRHGK 475
+ SD G Y C A + HGK
Sbjct: 5549 ESTMSDEGIYRCEAENAHGK 5568
Score = 97.5 bits (232), Expect = 5e-20
Identities = 118/443 (26%), Positives = 172/443 (38%), Gaps = 64/443 (14%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + +AP ++E ++ + Q L C+ G P P I+W+K G V ++ +
Sbjct: 5807 DVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIES 5866
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLRE----E 109
DAG Y C A N+YG+AR+ R + +RE
Sbjct: 5867 PDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPG 5926
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
F +++ GD+V ECL P G+P P++ W K+G L D +M G L++
Sbjct: 5927 FTTPLTIRRAKPGDSVTFECL-PFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLIL 5985
Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKI-------------------HIKPYLITGP 208
D G ++C+A N GT S A L I KP + G
Sbjct: 5986 SDVTFLSEGYFRCVATNEHGT-ASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGL 6044
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDD----GSLRLDNV 262
++ G+ V G P P V W + G+ P G+ + D L + N
Sbjct: 6045 YNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNA 6104
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---------NLSPNSV-NVESGNVAR- 311
DEGEYS EA N +G+ G L + P I P V +++ +V
Sbjct: 6105 SPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNH 6164
Query: 312 ----FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
F C G P P + W G + I PG R K + G L I DT D+
Sbjct: 6165 MPTIFDCLVVGHPAPEVEWFHNGKK--IVPG-GRIKIQSCG--GGSHALIILDTTLEDA- 6218
Query: 368 NTIVCSAVNYAGSSFVRGKLTVT 390
V +A N GS+ L VT
Sbjct: 6219 GEYVATAKNSHGSASSSAVLDVT 6241
Score = 96.3 bits (229), Expect = 1e-19
Identities = 125/542 (23%), Positives = 206/542 (38%), Gaps = 42/542 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLFFL 69
P ++ P + + + G P P + WY ++ + + G +
Sbjct: 2269 PEFVQAPQNHETTLEESVKFSAIVTGKPMPNVTWYLNNKKLIQSEEVKVKYVHETGKTSI 2328
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
R + + G EA N G ++ A L V E +F + +Q +G+ V
Sbjct: 2329 RIQKPLMEHN-GTIRVEAENVSGKVQA-TAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKF 2386
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAA 186
G PEP+V W NG+ + + + DG + + I AG C A N
Sbjct: 2387 TA-NVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPV 2445
Query: 187 GT--RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243
G+ R+ +A K+ P ED + G ++ P P + W + G
Sbjct: 2446 GSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKD-GVEI 2504
Query: 244 MPLGRVKVLD--DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPS 294
G K+++ DGSL+L L D+G + +AE+ G S L V P+
Sbjct: 2505 TSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPA 2564
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+N+ G+ TG P P + W + G + + + D + A +GV
Sbjct: 2565 FQSDIAPINLTEGDTLECKLLITGDPTPFVKWYI-GTQLVC---ATEDTEISNA--NGVY 2618
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKS 413
+ I+ D I C A N AG G L V + P P+ + T
Sbjct: 2619 TMKIHGVTA-DMTGKIKCVAYNKAGEVSTEGPLKVVA----PIPVEFETSLCDATCREGD 2673
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
+ PEP+++WY G+ L ++ + ++ T+ +KD+ SG C A
Sbjct: 2674 TLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAI 2733
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT---DTSVTLSWSQN 527
+ +GK LLV P ++V + G TK + H V D +L+W N
Sbjct: 2734 NEYGKATSEATLLVLPRGEPPDFLEWLSNVRARTG--TK-VVHKVVFTGDPKPSLTWYIN 2790
Query: 528 NK 529
NK
Sbjct: 2791 NK 2792
Score = 92.7 bits (220), Expect = 1e-18
Identities = 126/525 (24%), Positives = 200/525 (38%), Gaps = 43/525 (8%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C G P P + W + +H L G D GVY + N +G
Sbjct: 669 CEVEGWPEPELVWLVDDQ-PLRPSHDFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFG 727
Query: 93 TARSRNATLHVAV------LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
+ S+ A L V + EF+ E + +G+ V + + G P P + W NG
Sbjct: 728 SIESK-AELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVIT-GDPNPEIIWFING 785
Query: 147 QTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
+ L + DG L I+D + G C N G+ S LK+ + P
Sbjct: 786 KPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSA-SCDGRLKVRVPPAPP 844
Query: 206 T--GP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKVLD-DGSLRL 259
T P ED Q S+V F+ V G P P + + + G + G V+++ DG R+
Sbjct: 845 TFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTF--TLCGKELKNGEEGVEIVGHDGFYRI 902
Query: 260 D--NVIL-ADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
N + +GE +A+N G + LTV P+ V++G
Sbjct: 903 SIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEF 962
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A F T G P P + W + G++ + G K A +T+ D T
Sbjct: 963 AVFETTVRGNPNPEVTWFINGHK--MDQGSPGVKIEAHNHDHKLTI------DSAQYAGT 1014
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
++C A N G + +L V + + + PP ++T + + VF P+P
Sbjct: 1015 VLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPT 1074
Query: 429 IAWYFEGEALIQNHRRNVTN-DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
+ WY +GE L Q+ R + DG+ + +K++ D+G VA++ G L V
Sbjct: 1075 VTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134
Query: 486 -SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
P P R ++ G H T WS N +
Sbjct: 1135 KKPFAPEFD-LRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGR 1178
Score = 92.7 bits (220), Expect = 1e-18
Identities = 117/517 (22%), Positives = 201/517 (38%), Gaps = 69/517 (13%)
Query: 32 NCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRATHGRVHSDAGVYWCEATNS 90
N + G P P ++W+ G+ + D ++ A G + L R D G C A N
Sbjct: 5191 NVKVRGLPKPTLQWFLNGIPIKFDDRITLDDMADGNYCLTIRDVR-EEDFGTLKCIAKNE 5249
Query: 91 YGTARS----RNATLHVAVLREEFRLEPE------SKQSAQGDTVVLECLPPRGSPEPNV 140
GT + + H R++ R P ++ GD + +EC +P V
Sbjct: 5250 NGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVD-ANPTAEV 5308
Query: 141 YWKKNGQTLLFDGDSRM-HLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
W K+G+ + + + + VDG + I ++D G Y C+A N G E+ AT ++
Sbjct: 5309 EWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQ-ATYQV 5367
Query: 199 HIKPYL-----------ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
I ++ I P ED G + C+V P V+W + +PL
Sbjct: 5368 EILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG----LPL 5423
Query: 247 GR-----VKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------- 292
++ +DG+ L +++ D G Y C A N+ G ++ S + V P
Sbjct: 5424 RADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE 5483
Query: 293 ---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P + + G+ C TG P P + W G + R +
Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ---LLRNGPRTVIETSP- 5539
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---------GKLTVTSDDDRPPPII 400
DG LT+N++ +D C A N G + + GK D+ PP
Sbjct: 5540 -DGSCSLTVNESTMSDE-GIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKF 5597
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLK 455
S+ ++ + ++ C P P + W +G LI++ R +N+ + L +K
Sbjct: 5598 ILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIK 5657
Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+ D GTY CVA++ +G + +D + +
Sbjct: 5658 NATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGV 5694
Score = 91.5 bits (217), Expect = 3e-18
Identities = 110/474 (23%), Positives = 186/474 (39%), Gaps = 49/474 (10%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
+P ++WYK + ++H G + A + D Y +N+ G S
Sbjct: 4898 APVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSS 4957
Query: 98 NATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
A V VL+ L+ + Q V L+ + G P+ + W KNGQ L D D
Sbjct: 4958 AALTVVKPNVLKIVDGLKDVDVEEPQ--PVELK-VKVEGIPKV-IKWYKNGQELKPDADG 5013
Query: 156 RM--HLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--- 208
+ G +L I ++++D G Y+ + N G S +H+K + P
Sbjct: 5014 FKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSV---VHVKSAKSSEPTSG 5070
Query: 209 -------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLR 258
+D + G +T QC + G+P P+V+W + + RV + +LR
Sbjct: 5071 ANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLR 5130
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARF 312
+ + +D G+Y A+N G+ ++ +TV + P + + G+ F
Sbjct: 5131 IRSAKKSDIGQYRVTAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPGDKKEF 5190
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
G P+PT+ W + G P D+ + DG LTI D + D T+ C
Sbjct: 5191 NVKVRGLPKPTLQWFLNG-----IPIKFDDRITLDDMADGNYCLTIRDVREEDF-GTLKC 5244
Query: 373 SAVNYAGSSFV-------RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
A N G+ G + DD R PP ++ +P+ C P
Sbjct: 5245 IAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANP 5304
Query: 426 EPIIAWYFEGEALIQNHRRNVTN--DGTLVLK--DLDKSDSGTYTCVASSRHGK 475
+ W+ +G+ + + N DG +K ++SD G Y CVA + G+
Sbjct: 5305 TAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQ 5358
Score = 90.2 bits (214), Expect = 8e-18
Identities = 118/480 (24%), Positives = 194/480 (40%), Gaps = 35/480 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + + G + L
Sbjct: 4400 PEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEI 4456
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ ++ D Y +N G A S +A L V + E + +G VL+
Sbjct: 4457 PNAQL-DDTADYKVVVSNDAGDADS-SAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVET 4514
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAG- 187
+ E + W KNG+ + D DG N LVI DA DA Y+ + + G
Sbjct: 4515 NKKPKE--IKWYKNGKEIT-PSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGN 4571
Query: 188 TRESAIA-TLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242
T +S+ A T+K+ K P +I G ED V GS + + G P V W ++ G
Sbjct: 4572 TADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSP-KTVKWYKNGKELPGA 4630
Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP- 299
+++ +DD L + + ++ D G+Y E N G+ ++SG +TV +P L P
Sbjct: 4631 AAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-EPKITFLKPL 4689
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
++ G A F+ +P + W G I P ++ D L I
Sbjct: 4690 KDQSITEGENAEFSVETNTKPR-IVKWYKNGQE--IKP---NSRFIIEQKTDTKYQLVIK 4743
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
+ ++D+ +T N AG + +LTV I+ G +Q + + VF
Sbjct: 4744 NAVRDDA-DTYKIVLENTAGEAESSAQLTVKKAKAGLCKIV-KGLEDQVVAKGAKMVFEV 4801
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTN-DGT---LVLKDLDKSDSGTYTCVASSRHGK 475
PE + W + + + D T L++ D D+G YT + GK
Sbjct: 4802 KIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGK 4860
Score = 88.2 bits (209), Expect = 3e-17
Identities = 79/284 (27%), Positives = 116/284 (40%), Gaps = 10/284 (3%)
Query: 30 TLNCRA--GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
TL C+ G P+P ++WY G LV + I A G++ ++ HG G C A
Sbjct: 2579 TLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMK-IHGVTADMTGKIKCVA 2637
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + VA + EF +GDT+ L + G PEP V W NG+
Sbjct: 2638 YNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAV-LLGEPEPVVSWYVNGK 2696
Query: 148 TLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYL 204
L + ++H G + I+D +G+ C A N G T E+ + L P
Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVI 263
+ +V A+TG+ V + GDP P + W + N L + D S N
Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816
Query: 264 LAD--EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
D GE C+AEN G VS + + Y + S + E
Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAE 2860
Score = 86.6 bits (205), Expect = 9e-17
Identities = 98/460 (21%), Positives = 167/460 (36%), Gaps = 28/460 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P D V + G P P++ W G V + ++ G +
Sbjct: 2365 EVPKFTTNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTI 2424
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVL 127
+ AG CEATN G+ + R+ L V + + F E + +G+ ++
Sbjct: 2425 EIS-AVTPEQAGELSCEATNPVGS-KKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLM 2482
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNA 185
+ P+P + W K+G + DG ++ + G+L + + D GR A +
Sbjct: 2483 DAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESE 2542
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV--TFQCR--VGGDPLPDVLW----RR 237
G E + + + +P + +A + T +C+ + GDP P V W +
Sbjct: 2543 FGVAECSASLGVVKGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQL 2602
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
+ + + ++++ V G+ C A N G VS G L V P +
Sbjct: 2603 VCATEDTEISNANGVY--TMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEF 2660
Query: 298 SPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+ G+ + G PEP + W V G + K H+ G
Sbjct: 2661 ETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKK---LEESQNIKIHSEK---GTYT 2714
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+TI D D +VC A+N G + L V + PP SN +
Sbjct: 2715 VTIKDITC-DYSGQVVCEAINEYGKATSEATLLVLPRGE--PPDFLEWLSNVRARTGTKV 2771
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVL 454
V P+P + WY + ++ + VT+D T L
Sbjct: 2772 VHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTL 2811
Score = 86.2 bits (204), Expect = 1e-16
Identities = 80/296 (27%), Positives = 130/296 (43%), Gaps = 31/296 (10%)
Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAG-GLFFLRATHG 74
+PL+V + L G+P P + W+K + + ++H G G L
Sbjct: 3489 RPLEVR--EQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFAKDEGSGHHTLTIKQA 3546
Query: 75 RVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R D GVY C+ATN G A++ N + + F + + QG L +
Sbjct: 3547 R-GEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAEL-VVRVE 3604
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGN----LVIQDARQTDAGRYQCIARNAAG 187
G PEP V W K+G + D H+++ G N LVI+D D G+Y C A N AG
Sbjct: 3605 GKPEPEVKWFKDGVPIAIDNQ---HVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAG 3661
Query: 188 TRESAIATLKI-----------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
++ + LKI +KP I ++ A G +V +C+V + P + +
Sbjct: 3662 -KDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFF 3720
Query: 237 RSAGGGNMPLG-RVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ + +++VL+DG+++L N D G Y CEA N G + + L +
Sbjct: 3721 KNDQPVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776
Score = 81.0 bits (191), Expect = 5e-15
Identities = 123/534 (23%), Positives = 198/534 (37%), Gaps = 37/534 (6%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP ++ + V + A C+ G+ P ++W+K G + D
Sbjct: 4017 APGFFKELSAIQVKETETAKFECKVSGT-KPDVKWFKDGTPLKEDKRVHFESTDDGTQRL 4075
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
D G Y E +N G A S+ V + + QG ++L +
Sbjct: 4076 VIEDSKTDDQGNYRIEVSNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLS-V 4134
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCI-ARNAAG 187
G P+ V W K +T+ +++ V L I+ A +D G Y+ + + ++
Sbjct: 4135 EVEGKPK-TVKWYKGTETVTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFS 4193
Query: 188 TRESAIATL-----KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
SA T+ KI + P G D G+ + + + G P DV W ++ G
Sbjct: 4194 VESSATVTVTKAAEKISL-PSFKKGLADQSVPKGTPLVLEVEIEGKP-KDVKWYKN--GD 4249
Query: 243 NMPLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
+ G+V+ L +G RL + D GEYS A N G + + + V P I
Sbjct: 4250 EIKDGKVEDLGNGKYRLTIPDFQEKDVGEYSVTAANEAGEIESKAKVNVSAKPEIVSGLV 4309
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
V+ G A F G P + W G I ++D DG L I +
Sbjct: 4310 PTTVKQGETATFNVKVKG-PVKGVKWYKNGKE--IPDAKTKDN------GDGSYSLEIPN 4360
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDD--DRPPPIITNGPSNQTLPIKSMAVF 417
D+ + V + N AG + LTV +DD D+ P I +G T+ A F
Sbjct: 4361 AQVEDAADYKVVVS-NDAGDADSSAALTVKLADDGKDKVKPEIVSGLIPTTVKQGETATF 4419
Query: 418 PCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475
+ P + WY G+ I N + DG +L + + D+ Y V S+ G
Sbjct: 4420 N-VKVKGPVKQVKWYKNGKE-IPNAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSNDAGD 4477
Query: 476 YVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
S AL V P I + + + +P + + W +N K
Sbjct: 4478 ADSSAALTVKL---PGIAIVKGLEDAEVPKGKKAVLQVETNKKPKEIKWYKNGK 4528
Score = 80.6 bits (190), Expect = 6e-15
Identities = 102/403 (25%), Positives = 167/403 (41%), Gaps = 33/403 (8%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA-GGL 66
G+AP + D + + ++ + P P I W K GV + SD H I+ G
Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQG 122
L ++ D G +A + +G A +A+L V + + F+ + +G
Sbjct: 2520 LKLSILQTKLE-DKGRITIKAESEFGVAEC-SASLGVVKGRPMAKPAFQSDIAPINLTEG 2577
Query: 123 DTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQC 180
DT LEC L G P P V W Q + D+ + +G + I G+ +C
Sbjct: 2578 DT--LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKC 2635
Query: 181 IARNAAGTRESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+A N AG S LK+ + P + T D + G ++ + + G+P P V W
Sbjct: 2636 VAYNKAG-EVSTEGPLKV-VAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693
Query: 238 SAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---D 291
+ G +K+ + ++ + ++ G+ CEA N G ++ L V +
Sbjct: 2694 N-GKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGE 2752
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP ++V +G TG P+P++ W + N+ I+ + D Y T V D
Sbjct: 2753 PPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYIN-NKEIL----NSDLY--TIVTD 2805
Query: 352 GVT-VLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSD 392
T LTIN + + I+C A N AG S +T TSD
Sbjct: 2806 DKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTANMITYTSD 2848
Score = 75.8 bits (178), Expect = 2e-13
Identities = 99/334 (29%), Positives = 140/334 (41%), Gaps = 50/334 (14%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSI 60
D + G+AP PL + A+ T C G+P P+I+W K G+ + SD +
Sbjct: 5916 DSSIREGKAPGFTT-PLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKME 5974
Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-------EEFRLE 113
A G L + S+ G + C ATN +GTA S A L + R E E
Sbjct: 5975 AAADGTQRLILSDVTFLSE-GYFRCVATNEHGTA-STKAELVIEGDRTIGSRPLPEVNGE 6032
Query: 114 PES----------KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--- 160
PE S VV + G P P V W K+GQ ++ DG ++
Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092
Query: 161 DGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---------PE 209
+ G +LVI +A D G Y A N G+ ++ +L I I+P I P
Sbjct: 6093 ERGIHHLVIVNASPDDEGEYSLEATNKLGSAKTE-GSLNI-IRPRHIADADERGGMPFPP 6150
Query: 210 DVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG----SLR 258
V Q + F C V G P P+V W + G +P GR+K+ G +L
Sbjct: 6151 GFVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHN-GKKIVPGGRIKIQSCGGGSHALI 6209
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ + L D GEY A+NS G+ S+S L V P
Sbjct: 6210 ILDTTLEDAGEYVATAKNSHGSASSSAVLDVTVP 6243
Score = 75.4 bits (177), Expect = 2e-13
Identities = 74/289 (25%), Positives = 114/289 (39%), Gaps = 23/289 (7%)
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DG--SLRLDNVILADEGEYSCE 273
SS +V G PLPD+ W + + D DG ++ +D V + D G Y+C
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 274 AENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
A N G S S + V PP+ + G+V F C G PEP + W
Sbjct: 623 ATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWL 682
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
V+ R + +DG T L I D +D+ N GS + +
Sbjct: 683 VDDQPL-------RPSHDFRLQYDGQTAKLEIRDAQPDDT-GVYTVKIQNEFGSIESKAE 734
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHR- 443
L V +D D+ + + + ++ T P P I W+ G+ L ++ +
Sbjct: 735 LFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKV 794
Query: 444 RNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+ ++ DG L +KD+ + G TC S+R G G L V P P
Sbjct: 795 KFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP 843
Score = 74.5 bits (175), Expect = 4e-13
Identities = 119/491 (24%), Positives = 192/491 (39%), Gaps = 40/491 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFL 69
P II+ D V+ P L GSP ++WYK G + ++I ++
Sbjct: 4588 PKIIKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV 4646
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLE 128
V D G Y E N G+A N++ + V + L+P QS +G+ E
Sbjct: 4647 LEIPSSVVEDTGDYKVEVANEAGSA---NSSGKITVEPKITFLKPLKDQSITEGENA--E 4701
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARN 184
+ V W KNGQ + +SR + + LVI++A + DA Y+ + N
Sbjct: 4702 FSVETNTKPRIVKWYKNGQEI--KPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759
Query: 185 AAGTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
AG ES+ K L + G ED V G+ + F+ ++ G+P DV W R A
Sbjct: 4760 TAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEP-EDVRWLRDANV 4818
Query: 242 GNMPLGRV-KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
+ + + +DD + RL + L D GEY+ E N G + V + P I
Sbjct: 4819 ISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRG 4878
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
++ + G+ F + P + W N I P A + L I
Sbjct: 4879 LENIEIPEGDDDVFKVEVSA-PVRQVKW--YKNDQEIKP---NSHLEAKKIGPKKYELAI 4932
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N +D + V + N AG LTV + I +G + +
Sbjct: 4933 NRAQLDDGADYKVVLS-NAAGDCDSSAALTVVKPNVLK---IVDGLKDVDVEEPQPVELK 4988
Query: 419 CTAICTPEPIIAWYFEGEAL------IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
P+ +I WY G+ L + + + + +L + KSD G Y V +
Sbjct: 4989 VKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGND 5047
Query: 473 HGKYVWSGALL 483
G+ V+SG+++
Sbjct: 5048 KGE-VYSGSVV 5057
Score = 72.5 bits (170), Expect = 2e-12
Identities = 87/393 (22%), Positives = 159/393 (40%), Gaps = 30/393 (7%)
Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
V+ +F + + ++ +G + V EC+ P + W K+G+ + R+ G
Sbjct: 2884 VMAPKFITKIKDTKAKKGHSAVFECVVP-DTKGVCCKWLKDGKEIELIARIRVQTRTGPE 2942
Query: 165 ------LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIK------PYLITGPED 210
LV+ + DAG+Y CI N AG T E+ + ++ K P I +D
Sbjct: 2943 GHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQD 3002
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
+T V +C+V G+P P V W V+ ++ + + + L+ +G+
Sbjct: 3003 KTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTITSSELSHQGK 3062
Query: 270 YSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
Y+C AEN+ G +LTV + P + + G +C+ G P+P + +
Sbjct: 3063 YTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYS 3122
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVT--VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
T + ++ A T + I+ K D + A N G++ K
Sbjct: 3123 FSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDI-VSYKAIATNSIGTATSTSK 3181
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NH-- 442
+T + P+ G ++ K + P + W+ + + + + NH
Sbjct: 3182 ITTKVE----APVFEQGLKKTSVKEKEEIKME-VKVGGSAPDVEWFKDDKPVSEDGNHEM 3236
Query: 443 RRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
++N T TLV+K +D+G YT AS+ G
Sbjct: 3237 KKNPETGVFTLVVKQAATTDAGKYTAKASNPAG 3269
Score = 72.5 bits (170), Expect = 2e-12
Identities = 119/493 (24%), Positives = 193/493 (39%), Gaps = 42/493 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + G + L
Sbjct: 4302 PEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD--NGDGSYSLEI 4358
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSA------QGDT 124
+ +V DA Y +N G A S +A L V + + + +++PE QG+T
Sbjct: 4359 PNAQVE-DAADYKVVVSNDAGDADS-SAALTVKLADDGKDKVKPEIVSGLIPTTVKQGET 4416
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ +G P V W KNG+ + + ++ + +L I +A+ D Y+ + N
Sbjct: 4417 ATFN-VKVKG-PVKQVKWYKNGKEIP-NAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSN 4473
Query: 185 AAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
AG +S+ A T+K+ ++ G ED G Q P ++ W ++ G
Sbjct: 4474 DAGDADSSAALTVKLP-GIAIVKGLEDAEVPKGKKAVLQVETNKKP-KEIKWYKN-GKEI 4530
Query: 244 MPLGRVKVLDDGSLRLDNVILA----DEGEYSCEAENSVG-AVSASGYLTVYDP---PSI 295
P + + DG + VI D EY + G +S LTV P P I
Sbjct: 4531 TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKI 4590
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
V G+ + +G P+ T+ W G PG + + D V
Sbjct: 4591 IKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKE---LPGAAAKTIKIQKIDDNKYV 4646
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L I + D+ + V N AGS+ GK+TV P +Q++ A
Sbjct: 4647 LEIPSSVVEDTGDYKV-EVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGENA 4700
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
F P I+ WY G+ + N R + LV+K+ + D+ TY V +
Sbjct: 4701 EFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759
Query: 472 RHGKYVWSGALLV 484
G+ S L V
Sbjct: 4760 TAGEAESSAQLTV 4772
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 15/207 (7%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG---QTLLFDGDSRMHLVDGGN--LVIQD 169
E + A+ DT+ + L G P+P++ WK G T +++ G L I
Sbjct: 6417 EKRYCAENDTLTI-VLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITG 6475
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
+ + G+YQC A+N G + I + + +P I + + + RV G+P
Sbjct: 6476 FSKENVGQYQCFAKNDYGDAQQNIM-VDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P++ W + + R+K + DG SL +++ + D G YSC A N G + S
Sbjct: 6535 FPELKWMKE-WRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 6593
Query: 286 YLTVY---DPPSINLSPNSVNVESGNV 309
+TV D + L V +ES V
Sbjct: 6594 TVTVEAEGDYNDVELPRRRVTIESRRV 6620
Score = 64.1 bits (149), Expect = 6e-10
Identities = 94/423 (22%), Positives = 157/423 (37%), Gaps = 33/423 (7%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
S AP ++ D TV + A G+P+P + W+ G + + + A
Sbjct: 942 SRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHD 1001
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-------SKQSA 120
+ AG C A N+ G ++ + VL E + +P K
Sbjct: 1002 HKLTIDSAQY--AGTVLCRAENAVGRFETK---ARLVVLAPEKQKKPPKFVEILVDKTET 1056
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179
+TVV E + G P+P V W G+ L + DG + I++ + DAG +
Sbjct: 1057 VDNTVVFE-VRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115
Query: 180 CIARNAAGTRESAIATLKIHIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
+A N+ G+ E+ A L + KP+ P + + GS F G PLP W
Sbjct: 1116 AVATNSEGSDETK-AKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWS 1174
Query: 237 RSA-----GGGNMPLGRVKVLDDGS--LRLDNVILADEGEY---SCEAENSVGAVSASGY 286
+ G + R + DG+ L +D E + S AEN++GA
Sbjct: 1175 VNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQ 1234
Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTC--TATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
LT+ +P ++ ++ S V + PE T ++E + T +
Sbjct: 1235 LTI-EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEATTTITMETSLTST-KTTTMSTT 1292
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
T+ GVTV T +++ + I + S K+ V S D + P
Sbjct: 1293 EVTSTVGGVTVET-KESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVREGTP 1351
Query: 405 SNQ 407
+
Sbjct: 1352 KRR 1354
Score = 61.7 bits (143), Expect = 3e-09
Identities = 66/257 (25%), Positives = 93/257 (36%), Gaps = 16/257 (6%)
Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
+VG ++S T P S V A C G P P + W+ EG
Sbjct: 3801 TVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEV--- 3857
Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD--- 393
MS + A DG LT ++ + D+ C A N GS++ G + VT +
Sbjct: 3858 -EMSA-RVRAEHKDDGTLTLTFDNVTQADA-GEYRCEAENEYGSAWTEGPIIVTLEGAPK 3914
Query: 394 -DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DG 450
D P + + AV P+P + WY GE L + R + N DG
Sbjct: 3915 IDGEAPDFLQPVKPAVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDG 3974
Query: 451 T--LVLKDLDKSDSGTYTCVASSRHGKYVWSG-ALLVDSPINPNIHFFRAADVSSLPGPP 507
T L + + D Y C AS+ G VWS L V P FF+ +
Sbjct: 3975 TQRLTVTNAKLDDMDEYRCEASNEFGD-VWSDVTLTVKEPAQVAPGFFKELSAIQVKETE 4033
Query: 508 TKPITHNVTDTSVTLSW 524
T V+ T + W
Sbjct: 4034 TAKFECKVSGTKPDVKW 4050
Score = 60.9 bits (141), Expect = 5e-09
Identities = 54/215 (25%), Positives = 86/215 (40%), Gaps = 25/215 (11%)
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
T +DD PI T + L A+F C +P P + W F+G+ L N R +
Sbjct: 7518 TKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIE 7577
Query: 448 NDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLP 504
D L+L D G Y C A + +G S L+ + + S P
Sbjct: 7578 QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI-------------SGETPSRP 7624
Query: 505 GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564
G P ++ +DT + + W G + + G + R ++G N + W+ ++
Sbjct: 7625 GRPEAELS---SDTEIFIQWEAPE--GPTYLEGITYRLEYR--VAGPND--HGDPWITVS 7675
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
++ +VK L P Y F V +N GL PS
Sbjct: 7676 EKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPS 7710
Score = 60.5 bits (140), Expect = 7e-09
Identities = 89/376 (23%), Positives = 149/376 (39%), Gaps = 27/376 (7%)
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
D +G +A NAAG+ E+ LK+ P PE VT V D
Sbjct: 1944 DTTMFGSGTVSVVASNAAGSVETK-TELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMD 2002
Query: 229 --PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVGAVSA 283
L L++ G + G+ V ++I+ D G+ + EA N VG+ +
Sbjct: 2003 VIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSES 2062
Query: 284 SGYLTVYDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
S LTV P P + P SV ++ A F T +G P PT+ W++ N I+
Sbjct: 2063 SAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTI--NEKIV----E 2116
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP--PP 398
+ T + V L I++ K + T+ +A N AG + L V + P
Sbjct: 2117 ESRTITTIKTEDVYTLKISNA-KIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGT--LVL 454
+T+ +++ P++ +P ++W G+ L ++ V + DGT + +
Sbjct: 2176 QLTDKVADEGEPLRWNLELDGP---SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTI 2232
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514
+ SGT T A + G+ S + V+ N F +A + +
Sbjct: 2233 AEAKPEMSGTLTAKAKNAAGECETSAKVTVNGG-NKKPEFVQAPQNHETTLEESVKFSAI 2291
Query: 515 VTDTSV-TLSWSQNNK 529
VT + ++W NNK
Sbjct: 2292 VTGKPMPNVTWYLNNK 2307
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 12/171 (7%)
Query: 24 ARHQPATLNCRAGGSPSPAIRW-YKG-GVLVVSDTHR-SILPAGGLFFLRATHGRVHSDA 80
A + T+ G P P I+W ++G + S T + + GG A G +
Sbjct: 6422 AENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENV 6481
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N YG A+ +N + +A R F ++P ++ + + G P P +
Sbjct: 6482 GQYQCFAKNDYGDAQ-QNIMVDLAT-RPNF-IQPLVNKTFSSAQPMRMDVRVDGEPFPEL 6538
Query: 141 YWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG 187
W K + ++ SR+ V G +L+I D D+G Y C+A N AG
Sbjct: 6539 KWMKEWRPIV--ESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAG 6587
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + DV + ++QPA C SP+P + W G ++ S+ +I + L
Sbjct: 7527 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 7586
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARS 96
H + D G Y C A N YGT +S
Sbjct: 7587 LNHAAPY-DLGEYVCTAINEYGTDKS 7611
Score = 39.9 bits (89), Expect = 0.011
Identities = 21/83 (25%), Positives = 36/83 (43%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ ++ T + QP ++ R G P P ++W K +V + + G
Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566
Query: 72 THGRVHSDAGVYWCEATNSYGTA 94
+ + D+G+Y C A N G A
Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQA 6589
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P P + W E ++++ R DG +L++ D DSG Y+CVA + G+ S
Sbjct: 6534 PFPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 6593
Query: 481 ALLVDS 486
+ V++
Sbjct: 6594 TVTVEA 6599
Score = 33.5 bits (73), Expect = 0.93
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 4/88 (4%)
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILAD 266
DV + F+C V P P V W G RV + D + L L++ D
Sbjct: 7536 DVYLRKNQPAIFECAVSASPAPKVTW-DFQGKILESNDRVTIEQDNNVARLILNHAAPYD 7594
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPS 294
GEY C A N G +S L + PS
Sbjct: 7595 LGEYVCTAINEYGTDKSSCRLISGETPS 7622
Score = 33.5 bits (73), Expect = 0.93
Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIA 182
+ EC SP P V W G+ L + + R+ + N L++ A D G Y C A
Sbjct: 7546 IFECAVS-ASPAPKVTWDFQGKIL--ESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTA 7602
Query: 183 RNAAGTRESA 192
N GT +S+
Sbjct: 7603 INEYGTDKSS 7612
>U33058-1|AAB00542.1| 6632|Caenorhabditis elegans UNC-89 protein.
Length = 6632
Score = 146 bits (353), Expect = 1e-34
Identities = 178/689 (25%), Positives = 281/689 (40%), Gaps = 110/689 (15%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHRSILPAG 64
VT+ + P + DV QP L C+ SP P + WYK G +V SD + L
Sbjct: 5695 VTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPD 5754
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLREEFR--- 111
G+ L V+ D G+Y ATN GTA+ R++ + R+ F
Sbjct: 5755 GVATLLIP-SCVYDDDGIYRVIATNPSGTAQDKGTATVKKLPRDSGARRSADRDVFDANK 5813
Query: 112 ----LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-- 164
+EP E+ + + + L C G P+P + W K+G+ + G R+ L++ +
Sbjct: 5814 APKLMEPLENIRIPEKQSFRLRC-KFSGDPKPTIKWFKDGERVFPYG--RLQLIESPDGV 5870
Query: 165 --LVIQDARQTDAGRYQCIARNAAGTRESA--IATLKIHIKPYLI------------TGP 208
LV+ A + DAG Y+C+A N G+ ++ + ++ KP I T P
Sbjct: 5871 CELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTP 5930
Query: 209 EDVV-AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL--DNVI 263
+ A+ G SVTF+C G+P P + W + G ++K+ DG+ RL +V
Sbjct: 5931 LTIRRAKPGDSVTFECLPFGNPFPSIKWLKD-GLELFSDEKIKMEAAADGTQRLILSDVT 5989
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDP--------PSINLSPN-----------SVNV 304
EG + C A N G S L + P +N P ++++
Sbjct: 5990 FLSEGYFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMSI 6049
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKN 364
GNV ATG P PT+ W +G + I+ G + T G+ L I + +
Sbjct: 6050 HEGNVVEMIVCATGIPTPTVKWYKDG-QEIVGDGPDGKRVIFTDE-RGIHHLVIVNASPD 6107
Query: 365 DSRNTIVCSAVNYAGSSFVRGKLT------VTSDDDRP----PPIITNGPSNQTLPIKSM 414
D A N GS+ G L + D+R PP N+ +
Sbjct: 6108 D-EGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMP 6166
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVAS 470
+F C + P P + W+ G+ ++ R + + G L++ D D+G Y A
Sbjct: 6167 TIFDCLVVGHPGPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATAK 6226
Query: 471 SRHGKYVWSGALLVDSPINPNIHF---------------FRAADVSSLPGPPTK-PITHN 514
+ HG S L V P +I F F+ + +SLP PP + P
Sbjct: 6227 NSHGSASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKELNTASLPTPPDRGPFIKE 6286
Query: 515 VTDTSVTLSWSQNNKIGSS-SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYV 573
VT +TLSW + + Y +E+ RE + W ++ + +
Sbjct: 6287 VTGHYLTLSWIPTKRAPPRYPQVTYVIEI--REL--------PEKQWSLLEYNIPEPVCK 6336
Query: 574 VKSLIPGITYMFIVRTENSHGLSGPSPVS 602
V++L G +Y F VR EN +G+S PSP S
Sbjct: 6337 VRNLELGKSYQFRVRAENIYGISDPSPAS 6365
Score = 140 bits (339), Expect = 5e-33
Identities = 139/499 (27%), Positives = 208/499 (41%), Gaps = 62/499 (12%)
Query: 28 PATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-PAGGLFFLRATHGRVHSDAGVYWCE 86
P + C +P+ + W+K G + H I G ++ SD GVY C
Sbjct: 5293 PMFIECHVDANPTAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFE-ESDIGVYMCV 5351
Query: 87 ATNSYGTARSRNATLHVAVL-------REEF--RLEP--ESKQSAQGDTVVLECLPPRGS 135
A N G A ++ AT V +L R E+ ++ P E K G + L C
Sbjct: 5352 AVNELGQAETQ-ATYQVEILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSC-KVDAI 5409
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIARNAAGT-RESA 192
P +V W K+G L D + + + G L I D+ + D G Y+C+A NA GT S
Sbjct: 5410 PRASVVWYKDGLPLRADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSC 5469
Query: 193 IATLKI---HIK-----PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG-GGN 243
+K+ +K P+ G D+ A G S T +C V GDP P++ W R+ N
Sbjct: 5470 SVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRN 5529
Query: 244 MPLGRVKVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY----------- 290
P ++ DG SL ++ ++DEG Y CEAEN+ G V
Sbjct: 5530 GPRTVIETSPDGSCSLTVNESTMSDEGIYRCEAENAHGKAKTQATAHVQMALGKTEKPKM 5589
Query: 291 ---DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
PP L + ++V GNV C TG P P++ WS +G I SR ++ +
Sbjct: 5590 DEGKPPKFILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLI---EDSRFEW-SN 5645
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT-NGPSN 406
GV L I + +D T C A N GS+ K V DD ++T + P
Sbjct: 5646 EASKGVYQLRIKNATVHD-EGTYRCVATNENGSATT--KSFVRMDDGLGSGVVTASQPPR 5702
Query: 407 QTLPIKSMAV-------FPCTAICTPEPIIAWYFEGEALIQNHRRNV--TNDG--TLVLK 455
TL + + C +P P + WY +G + + R + + DG TL++
Sbjct: 5703 FTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDGAIVTPSDRIQISLSPDGVATLLIP 5762
Query: 456 DLDKSDSGTYTCVASSRHG 474
D G Y +A++ G
Sbjct: 5763 SCVYDDDGIYRVIATNPSG 5781
Score = 139 bits (336), Expect = 1e-32
Identities = 142/521 (27%), Positives = 221/521 (42%), Gaps = 71/521 (13%)
Query: 15 IEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH 73
I PL D TV QP L+C+ P ++ WYK G+ + +D+ SI A +
Sbjct: 5385 INPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDGLPLRADSRTSIQYEEDGTATLAIN 5444
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK---------QSAQGDT 124
D G Y C ATN++GT + + +++V V ++E + E E + +GD+
Sbjct: 5445 DSTEEDIGAYRCVATNAHGTINT-SCSVNVKVPKQEVKKEGEEPFFTKGLVDLWADRGDS 5503
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDGG-NLVIQDARQTDAGRYQCI 181
L+C G P P + W +NGQ LL +G + DG +L + ++ +D G Y+C
Sbjct: 5504 FTLKC-AVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVNESTMSDEGIYRCE 5561
Query: 182 ARNAAG-TRESAIATLKIHI----KPYLITGP--------EDVVAQTGSSVTFQCRVGGD 228
A NA G + A A +++ + KP + G D+ G+ + +C+V G
Sbjct: 5562 AENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKFILELSDMSVSLGNVIDLECKVTGL 5621
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVILADEGEYSCEAENSVGAVS- 282
P P V W + GG + R + ++ S LR+ N + DEG Y C A N G+ +
Sbjct: 5622 PNPSVKWSKD-GGPLIEDSRFEWSNEASKGVYQLRIKNATVHDEGTYRCVATNENGSATT 5680
Query: 283 ----------ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR 332
SG +T PP L V G + C P P M W +G
Sbjct: 5681 KSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLKLECKVDASPLPEMVWYKDG-- 5738
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--- 389
I+ P D+ + DGV L I +D V A N +G++ +G TV
Sbjct: 5739 AIVTPS---DRIQISLSPDGVATLLIPSCVYDDDGIYRVI-ATNPSGTAQDKGTATVKKL 5794
Query: 390 --------TSD----DDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
++D D P + N +P K C P+P I W+ +GE
Sbjct: 5795 PRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGER 5854
Query: 438 LIQNHRRNV--TNDGT--LVLKDLDKSDSGTYTCVASSRHG 474
+ R + + DG LV+ + D+G Y CVA + +G
Sbjct: 5855 VFPYGRLQLIESPDGVCELVVDSATRQDAGGYRCVAENTYG 5895
Score = 135 bits (327), Expect = 2e-31
Identities = 129/483 (26%), Positives = 199/483 (41%), Gaps = 34/483 (7%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + + G P P I WYK V + D + FF +D G Y C AT
Sbjct: 565 AKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCMAT 624
Query: 89 NSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
N YG A S +A V + +E F + K+ +GD + EC G PEP + W
Sbjct: 625 NEYGQA-STSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFEC-EVEGWPEPELVWL 682
Query: 144 KNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATL----- 196
+ Q L D R+ DG L I+DA+ D G Y +N G+ ES
Sbjct: 683 VDDQPLRPSHDFRLQ-YDGQTAKLEIRDAQPDDTGVYTVKIQNEFGSIESKAELFVQADP 741
Query: 197 -KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVK-VLDD 254
K H+ P E V G V F+ + GDP P+++W + G +VK + +D
Sbjct: 742 DKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFIN-GKPLSESEKVKFISED 800
Query: 255 G--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVNVESGNV 309
G L + +V +G +C+ N +G+ S G L V PP+ N V+ +
Sbjct: 801 GICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAPPTFNKPLEDKTVQEKST 860
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
F +G PEPT+ +++ G + ++ DG ++I +T +
Sbjct: 861 VVFEVDVSGWPEPTLTFTLCGKEL-----KNGEEGVEIVGHDGFYRISIPNTSMDKHDGE 915
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDD--RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP 427
IV A N G++ R +LTV +++ R P +QT+ AVF T P P
Sbjct: 916 IVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNP 975
Query: 428 IIAWYFEGEALIQNH---RRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
+ W+ G + Q + N + D +GT C A + G++ L+V
Sbjct: 976 EVTWFINGHKMDQGSPGVKIEAHNHDHKLTID-SAQYAGTVLCRAENAVGRFETKARLVV 1034
Query: 485 DSP 487
+P
Sbjct: 1035 LAP 1037
Score = 134 bits (324), Expect = 4e-31
Identities = 126/499 (25%), Positives = 209/499 (41%), Gaps = 32/499 (6%)
Query: 7 TSGEAPYIIEQPLDVT-VARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PA 63
T EAP + EQ L T V + + + GGS +P + W+K V D + + P
Sbjct: 3184 TKVEAP-VFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDDKPVSEDGNHEMKKNPE 3241
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQG 122
G+F L +DAG Y +A+N GTA S A + ++ + F E + +
Sbjct: 3242 TGVFTLVVKQAAT-TDAGKYTAKASNPAGTAESSAEAEVTQSLEKPTFVRELVTTEVKIN 3300
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGRYQ 179
+T L + +G P+P+V W K+GQ + D + V+G ++ I+DAR D+G+Y
Sbjct: 3301 ETATLS-VTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYA 3359
Query: 180 CIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
C A N AG E+ A +K + P + + + S T +V G P P V W +
Sbjct: 3360 CRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFK 3419
Query: 238 SAGGGNMP----LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG-AVSASGYLTVYD- 291
++ + + + SL +++ D G YSC A N G A++ + + + D
Sbjct: 3420 DDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCRARNEAGEALTTANFGIIRDS 3479
Query: 292 -PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
PP + V T G P P + W + ++ I +
Sbjct: 3480 IPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEW-FKDDKPI---NIDNSHIFGKDEG 3535
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G LTI + + C A N AG + + V + + P + G +
Sbjct: 3536 SGHHTLTIKQA-RGEDVGVYTCKATNEAGEAKTTANMAVQEEIEAP--LFVQGLKPYEVE 3592
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTY 465
A PEP + W+ +G + +++ + G TLV+KD + +D G Y
Sbjct: 3593 QGKPAELVVRVEGKPEPEVKWFKDGVPIAIDNQHVIEKKGENGSHTLVIKDTNNADFGKY 3652
Query: 466 TCVASSRHGKYVWSGALLV 484
TC A+++ GK G L +
Sbjct: 3653 TCQATNKAGKDETVGELKI 3671
Score = 126 bits (303), Expect = 1e-28
Identities = 139/544 (25%), Positives = 222/544 (40%), Gaps = 78/544 (14%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GE P+ + +D+ R TL C G P P I+WY+ G L+ + I +
Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQLLRNGPRTVIETSPDGSC 5543
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV--AVLREE-----------FRLEPE 115
+ SD G+Y CEA N++G A+++ AT HV A+ + E F LE
Sbjct: 5544 SLTVNESTMSDEGIYRCEAENAHGKAKTQ-ATAHVQMALGKTEKPKMDEGKPPKFILELS 5602
Query: 116 SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN-----LVIQDA 170
+ G+ + LEC G P P+V W K+G L+ DSR + + L I++A
Sbjct: 5603 DMSVSLGNVIDLEC-KVTGLPNPSVKWSKDGGPLI--EDSRFEWSNEASKGVYQLRIKNA 5659
Query: 171 RQTDAGRYQCIARNAAGTRES-AIATLKIHIKPYLITGPE---------DVVAQTGSSVT 220
D G Y+C+A N G+ + + + + ++T + DV G +
Sbjct: 5660 TVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGVVTASQPPRFTLKMGDVRTTEGQPLK 5719
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDG--SLRLDNVILADEGEYSCEAEN 276
+C+V PLP+++W + G P R+++ DG +L + + + D+G Y A N
Sbjct: 5720 LECKVDASPLPEMVWYKD-GAIVTPSDRIQISLSPDGVATLLIPSCVYDDDGIYRVIATN 5778
Query: 277 SVGAVSASGYLTVYDPP--------------SINLSP------NSVNVESGNVARFTCTA 316
G G TV P N +P ++ + R C
Sbjct: 5779 PSGTAQDKGTATVKKLPRDSGARRSADRDVFDANKAPKLMEPLENIRIPEKQSFRLRCKF 5838
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
+G P+PT+ W +G R +FP + DGV L ++ + D+ C A N
Sbjct: 5839 SGDPKPTIKWFKDGER--VFP---YGRLQLIESPDGVCELVVDSATRQDA-GGYRCVAEN 5892
Query: 377 YAGSSFVRGKLTVTSDDDRPPPI---ITNGPS-NQTLPIK-------SMAVFPCTAICTP 425
GS+ + V D +P I I G + T P+ F C P
Sbjct: 5893 TYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPGFTTPLTIRRAKPGDSVTFECLPFGNP 5952
Query: 426 EPIIAWYFEGEALIQNH--RRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P I W +G L + + DGT L+L D+ G + CVA++ HG
Sbjct: 5953 FPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLSEGYFRCVATNEHGTASTKAE 6012
Query: 482 LLVD 485
L+++
Sbjct: 6013 LVIE 6016
Score = 122 bits (295), Expect = 1e-27
Identities = 126/498 (25%), Positives = 203/498 (40%), Gaps = 46/498 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLF 67
E P + + + V ++ ATL+ G P P++ W K G V +D+ I + G +
Sbjct: 3284 EKPTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQPVQTDSSHVIAKVEGSGSY 3343
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEF--RLEPESKQSAQGDT 124
+ R+ D+G Y C ATN G A++ N + ++ EF +L P + + T
Sbjct: 3344 SITIKDARLE-DSGKYACRATNPAGEAKTEANFAVVKNLVPPEFVEKLSPLEVKEKESTT 3402
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGD---SRMHLVDGGNLVIQDARQTDAGRYQCI 181
+ ++ + G+PEP+V W K+ + D + V +L I DARQ D G Y C
Sbjct: 3403 LSVKVV---GTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIYSCR 3459
Query: 182 ARNAAG--TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
ARN AG + ++ I P + + ++ + V G P+P+V W +
Sbjct: 3460 ARNEAGEALTTANFGIIRDSIPPEFTQKLRPLEVREQETLDLKVTVIGTPVPNVEWFKDD 3519
Query: 240 GGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
N+ + D+GS L + D G Y+C+A N G + + V +
Sbjct: 3520 KPINIDNSHIFGKDEGSGHHTLTIKQARGEDVGVYTCKATNEAGEAKTTANMAVQEEIEA 3579
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV--F 350
P VE G A G+PEP + W +G I D H
Sbjct: 3580 PLFVQGLKPYEVEQGKPAELVVRVEGKPEPEVKWFKDGVPIAI------DNQHVIEKKGE 3633
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--------TSDDDRPPPIITN 402
+G L I DT+ D C A N AG G+L + T+++ +P +
Sbjct: 3634 NGSHTLVIKDTNNADF-GKYTCQATNKAGKDETVGELKIPKYSFEKQTAEEVKP---LFI 3689
Query: 403 GPSNQTLPIK-SMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR-NVTNDGT--LVLKDL 457
P +T ++ V C P I ++ + + I H + V DG L +++
Sbjct: 3690 EPLKETFAVEGDTVVLECKVNKESHPQIKFFKNDQPVEIGQHMQLEVLEDGNIKLTIQNA 3749
Query: 458 DKSDSGTYTCVASSRHGK 475
K D G Y C A + GK
Sbjct: 3750 KKEDVGAYRCEAVNVAGK 3767
Score = 106 bits (255), Expect = 8e-23
Identities = 116/490 (23%), Positives = 195/490 (39%), Gaps = 39/490 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP I D T + L C+ G P P + W + ++ ++ G+ +
Sbjct: 2992 KAPEFIVALQDKTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQES-ITVESVEGVERV 3050
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLEC 129
T + S G Y C A N+ GT+++ A L V F E ++K+ + G+ +VL C
Sbjct: 3051 TITSSEL-SHQGKYTCIAENTEGTSKT-EAFLTVQGEAPVFTKELQNKELSIGEKLVLSC 3108
Query: 130 LPPRGSPEPNVYWKKNGQTLLFD----GDSRMHLV-DGGN----LVIQDARQTDAGRYQC 180
+GSP+P+V + +T + SR+ + D N +VI + D Y+
Sbjct: 3109 -SVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDIVSYKA 3167
Query: 181 IARNAAGTRES-AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS- 238
IA N+ GT S + T K+ P G + + + + +VGG PDV W +
Sbjct: 3168 IATNSIGTATSTSKITTKVE-APVFEQGLKKTSVKEKEEIKMEVKVGGS-APDVEWFKDD 3225
Query: 239 ---AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDP 292
+ GN + + +L + D G+Y+ +A N G +S V +
Sbjct: 3226 KPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKYTAKASNPAGTAESSAEAEVTQSLEK 3285
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD- 351
P+ + V+ A + T G P+P++ W +G + D H A +
Sbjct: 3286 PTFVRELVTTEVKINETATLSVTVKGVPDPSVEWLKDGQ------PVQTDSSHVIAKVEG 3339
Query: 352 -GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
G +TI D DS C A N AG + V + PP S +
Sbjct: 3340 SGSYSITIKDARLEDS-GKYACRATNPAGEAKTEANFAVVK--NLVPPEFVEKLSPLEVK 3396
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEAL-IQN----HRRNVTNDGTLVLKDLDKSDSGTY 465
K + TPEP + W+ + + I N ++ +L + D + D G Y
Sbjct: 3397 EKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVGSFSLTINDARQGDVGIY 3456
Query: 466 TCVASSRHGK 475
+C A + G+
Sbjct: 3457 SCRARNEAGE 3466
Score = 103 bits (246), Expect = 1e-21
Identities = 126/505 (24%), Positives = 191/505 (37%), Gaps = 36/505 (7%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
GEAP ++ + ++ + L+C GSP P + +Y +T + +
Sbjct: 3084 GEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYSFSETTKVETKITSSSRIAIEH 3143
Query: 69 LRA-THGRV------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
+ TH R+ D Y ATNS GTA S T + E E K+++
Sbjct: 3144 DQTNTHWRMVISQITKEDIVSYKAIATNSIGTATS---TSKITTKVEAPVFEQGLKKTSV 3200
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHL-VDGG--NLVIQDARQTDAGRY 178
+ ++ G P+V W K+ + + DG+ M + G LV++ A TDAG+Y
Sbjct: 3201 KEKEEIKMEVKVGGSAPDVEWFKDDKPVSEDGNHEMKKNPETGVFTLVVKQAATTDAGKY 3260
Query: 179 QCIARNAAGTRES---AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
A N AGT ES A T + KP + + + T V G P P V W
Sbjct: 3261 TAKASNPAGTAESSAEAEVTQSLE-KPTFVRELVTTEVKINETATLSVTVKGVPDPSVEW 3319
Query: 236 RRSAGGGNMPLGRV--KVLDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
+ V KV G S+ + + L D G+Y+C A N G V
Sbjct: 3320 LKDGQPVQTDSSHVIAKVEGSGSYSITIKDARLEDSGKYACRATNPAGEAKTEANFAVVK 3379
Query: 292 ---PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATA 348
PP + + V+ + G PEP++ W + I K A
Sbjct: 3380 NLVPPEFVEKLSPLEVKEKESTTLSVKVVGTPEPSVEWFKDDTPISIDNVHVIQKQTAVG 3439
Query: 349 VFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQT 408
F LTIND + D C A N AG + + D PP T
Sbjct: 3440 SFS----LTINDARQGDV-GIYSCRARNEAGEALTTANFGIIRDS--IPPEFTQKLRPLE 3492
Query: 409 LPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDG----TLVLKDLDKSDSG 463
+ + T I TP P + W+ + + + I N ++G TL +K D G
Sbjct: 3493 VREQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFGKDEGSGHHTLTIKQARGEDVG 3552
Query: 464 TYTCVASSRHGKYVWSGALLVDSPI 488
YTC A++ G+ + + V I
Sbjct: 3553 VYTCKATNEAGEAKTTANMAVQEEI 3577
Score = 102 bits (245), Expect = 1e-21
Identities = 117/404 (28%), Positives = 165/404 (40%), Gaps = 33/404 (8%)
Query: 11 APYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFF 68
AP +PL D TV G P P + + G L + I+ G +
Sbjct: 842 APPTFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTFTLCGKELKNGEEGVEIVGHDGFYR 901
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP------ESKQSAQG 122
+ + + G +A N +GTA SR A L V EE R P E + G
Sbjct: 902 ISIPNTSMDKHDGEIVAKAQNEHGTAESR-ARLTVEQEEEESRSAPTFLKDIEDQTVKTG 960
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRY 178
+ V E RG+P P V W NG + D S ++ N L I A+ AG
Sbjct: 961 EFAVFETTV-RGNPNPEVTWFINGHKM--DQGSPGVKIEAHNHDHKLTIDSAQY--AGTV 1015
Query: 179 QCIARNAAGTRES-----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDV 233
C A NA G E+ +A K P + D ++V F+ RV G+P P V
Sbjct: 1016 LCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTV 1075
Query: 234 LWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVY 290
W G RV++ + DGS+++ N+ + D GE A NS G+ LTV
Sbjct: 1076 TWYLK-GEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134
Query: 291 DPP---SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P +L P S+ VE G+ A F+ A G P PT WSV G + +R +
Sbjct: 1135 KKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGRKVRDGQEGARVTRDES 1194
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAV--NYAGSSFVRGKLTV 389
V DG ++LTI+ N + S V N G+ +LT+
Sbjct: 1195 TV-DGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQLTI 1237
Score = 102 bits (245), Expect = 1e-21
Identities = 116/492 (23%), Positives = 194/492 (39%), Gaps = 35/492 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P +++ P VT+ + A G P+P ++W +V + + ++ L+
Sbjct: 2075 PIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTINEKIVEESRTITTIKTEDVYTLKI 2134
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVA--VLREEFRLEPESKQSAQGDTVVLEC 129
++ ++ G A NS G S+ A L V V +F+ + K + +G+ +
Sbjct: 2135 SNPKI-EQTGTVKVTAQNSAG-QDSKQADLKVEPNVKAPKFKSQLTDKVADEGEPLRWNL 2192
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNA 185
SP V W NGQ L + +VD G ++ I +A+ +G +NA
Sbjct: 2193 ELDGPSPGTEVSWLLNGQPL--TKSDTVQVVDHGDGTYHVTIAEAKPEMSGTLTPKPKNA 2250
Query: 186 AGTRESA--IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW----RRSA 239
AG E++ + + KP + P++ SV F V G P+P+V W ++
Sbjct: 2251 AGECETSPKVTVNGGNKKPEFVQAPQNHETTLEGSVKFSAIVTGKPIPNVTWYLNNKKLI 2310
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPPSIN 296
+ + V S+R+ ++ G EAEN G V A+ L V + P
Sbjct: 2311 QSEEVKVKYVHETGKTSIRIQKPLMEHNGTIRVEAENVSGKVQATAQLKVDKKTEVPKFT 2370
Query: 297 LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTV 355
+ + V+ G +FT G PEP++ W++ G P ++ DK DG
Sbjct: 2371 TNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDK-------DGEHT 2423
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+ I+ + + C A N GS +L V D P ++ + +
Sbjct: 2424 IEISAVTP-EQAGELSCEATNPVGSKKRDVQLAVKKVGD--APTFAKNLEDRLITEGELT 2480
Query: 416 VFPCTA-ICTPEPIIAWYFEG-EALIQNHRRNV-TNDGTLVLKDLDK--SDSGTYTCVAS 470
+ I P+P I W +G E H + V DG+L L L D G T A
Sbjct: 2481 LMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAE 2540
Query: 471 SRHGKYVWSGAL 482
S G S +L
Sbjct: 2541 SEFGVAECSASL 2552
Score = 101 bits (241), Expect = 4e-21
Identities = 126/496 (25%), Positives = 202/496 (40%), Gaps = 45/496 (9%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGG 65
T AP +E TV Q A L C+ G P P I+W K G V +S R+ G
Sbjct: 3812 TGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEVEMSARVRAEHKDDG 3871
Query: 66 ---LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ- 121
L F T R CEA N YG+A + + L +++ E+ Q
Sbjct: 3872 TLTLTFDNVTQARRRR----IRCEAENEYGSAWTEGPI--IVTLEGAPKIDGEAPDFLQP 3925
Query: 122 --------GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDAR 171
G+T VLE G P+P+V W KNG+ L ++ +D G L + +A+
Sbjct: 3926 VKPVVVTVGETAVLEG-KISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQRLTVTNAK 3984
Query: 172 QTDAGRYQCIARNAAGTRESAIA-TLK--IHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
D Y+C A N G S + T+K + P + + + F+C+V G
Sbjct: 3985 LDDMDEYRCEASNEFGDVWSDVTLTVKEPAQVAPGFFKELSAIQVKETETAKFECKVSGT 4044
Query: 229 PLPDVLWRRSAGGGNMPLGRV--KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSAS 284
PDV W + G RV + DDG+ RL ++ D+G Y E N G ++
Sbjct: 4045 K-PDVKWFKD-GTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEVSNDAGVANSK 4102
Query: 285 GYLTVYDPPSINLSP--NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRD 342
LTV ++ + VNV G + G+P+ T+ W +G T+ S
Sbjct: 4103 VPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKPK-TVKW-YKGTETV----TSSQ 4156
Query: 343 KYHATAVFDGVTVLTINDTDKNDS-RNTIVCSAVNYAGSSFVRGKLTVTSDDDR-PPPII 400
V + L I + +D+ +V S +++ S +TVT ++ P
Sbjct: 4157 TTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVES--SATVTVTKAAEKISLPSF 4214
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDK 459
G ++Q++P + V P+ + WY G+ + ++ N L + D +
Sbjct: 4215 KKGLADQSVPKGTPLVLEVEIEGKPKD-VKWYKNGDEIKDGKVEDLGNGKYRLTIPDFQE 4273
Query: 460 SDSGTYTCVASSRHGK 475
D G Y+ A++ G+
Sbjct: 4274 KDVGEYSVTAANEAGE 4289
Score = 97.1 bits (231), Expect = 7e-20
Identities = 118/443 (26%), Positives = 172/443 (38%), Gaps = 64/443 (14%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA 63
D + +AP ++E ++ + Q L C+ G P P I+W+K G V ++ +
Sbjct: 5807 DVFDANKAPKLMEPLENIRIPEKQSFRLRCKFSGDPKPTIKWFKDGERVFPYGRLQLIES 5866
Query: 64 GGLFFLRATHGRVHSDAGVYWCEATNSYGTARS----------RNATLHVAVLRE----E 109
DAG Y C A N+YG+AR+ R + +RE
Sbjct: 5867 PDGVCELVVDSATRQDAGGYRCVAENTYGSARTSCDVNVIRGDRKPRDIDSSIREGKAPG 5926
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVI 167
F +++ GD+V ECL P G+P P++ W K+G L D +M G L++
Sbjct: 5927 FTTPLTIRRAKPGDSVTFECL-PFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLIL 5985
Query: 168 QDARQTDAGRYQCIARNAAGTRESAIATLKI-------------------HIKPYLITGP 208
D G ++C+A N GT S A L I KP + G
Sbjct: 5986 SDVTFLSEGYFRCVATNEHGT-ASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGL 6044
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDD----GSLRLDNV 262
++ G+ V G P P V W + G+ P G+ + D L + N
Sbjct: 6045 YNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNA 6104
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---------NLSPNSV-NVESGNVAR- 311
DEGEYS EA N +G+ G L + P I P V +++ +V
Sbjct: 6105 SPDDEGEYSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNH 6164
Query: 312 ----FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
F C G P P + W G + I PG R K + G L I DT D+
Sbjct: 6165 MPTIFDCLVVGHPGPEVEWFHNGKK--IVPG-GRIKIQSCG--GGSHALIILDTTLEDA- 6218
Query: 368 NTIVCSAVNYAGSSFVRGKLTVT 390
V +A N GS+ L VT
Sbjct: 6219 GEYVATAKNSHGSASSSAVLDVT 6241
Score = 94.3 bits (224), Expect = 5e-19
Identities = 125/542 (23%), Positives = 205/542 (37%), Gaps = 42/542 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLFFL 69
P ++ P + + G P P + WY ++ + + G +
Sbjct: 2269 PEFVQAPQNHETTLEGSVKFSAIVTGKPIPNVTWYLNNKKLIQSEEVKVKYVHETGKTSI 2328
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE--EFRLEPESKQSAQGDTVVL 127
R + + G EA N G ++ A L V E +F + +Q +G+ V
Sbjct: 2329 RIQKPLMEHN-GTIRVEAENVSGKVQA-TAQLKVDKKTEVPKFTTNMDDRQVKEGEDVKF 2386
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAA 186
G PEP+V W NG+ + + + DG + + I AG C A N
Sbjct: 2387 TA-NVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTIEISAVTPEQAGELSCEATNPV 2445
Query: 187 GT--RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGN 243
G+ R+ +A K+ P ED + G ++ P P + W + G
Sbjct: 2446 GSKKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKD-GVEI 2504
Query: 244 MPLGRVKVLD--DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPS 294
G K+++ DGSL+L L D+G + +AE+ G S L V P+
Sbjct: 2505 TSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESEFGVAECSASLGVVKGRPMAKPA 2564
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
+N+ G+ TG P P + W + G + + + D + A +GV
Sbjct: 2565 FQSDIAPINLTEGDTLECKLLITGDPTPFVKWYI-GTQLVC---ATEDTEISNA--NGVY 2618
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI-ITNGPSNQTLPIKS 413
+ I+ D I C A N AG G L V + P P+ + T
Sbjct: 2619 TMKIHGVTA-DMTGKIKCVAYNKAGEVSTEGPLKVVA----PIPVEFETSLCDATCREGD 2673
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
+ PEP+++WY G+ L ++ + ++ T+ +KD+ SG C A
Sbjct: 2674 TLKLRAVLLGEPEPVVSWYVNGKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAI 2733
Query: 471 SRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVT---DTSVTLSWSQN 527
+ +GK LLV P ++V + G TK + H V D +L+W N
Sbjct: 2734 NEYGKATSEATLLVLPRGEPPDFLEWLSNVRARTG--TK-VVHKVVFTGDPKPSLTWYIN 2790
Query: 528 NK 529
NK
Sbjct: 2791 NK 2792
Score = 93.1 bits (221), Expect = 1e-18
Identities = 123/500 (24%), Positives = 184/500 (36%), Gaps = 54/500 (10%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPA-GGLFFLRATHGRVHS 78
D V TL C G P P + W K GV++ D ++ A G LR + S
Sbjct: 5079 DTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLRIRSPK-KS 5137
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLREE-----FRLEPESKQSAQGDTVVLECLPPR 133
D G Y A N G+A S + + V E+ F + ++ + D + R
Sbjct: 5138 DIGQYRVSAKNEAGSATS-DCKVTVTEQGEQPSKPKFVIPLKTGAALPADKKEFN-VKVR 5195
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRES 191
G P P W NG + D + + GN L I+D R+ D G +CIA+N GT E+
Sbjct: 5196 GLPNPTFQWFLNGIPIKLDDRITLDDMADGNYCLTIRDVREEDFGTLKCIAKNENGTDET 5255
Query: 192 AIATLK-----------IHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
+ + P D G + +C V +P +V W +
Sbjct: 5256 VCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANPTAEVEWFKDGK 5315
Query: 241 G-GNMPLGRVKVLDDGSLRLDNVIL--ADEGEYSCEAENSVG--AVSASGYLTVYD---- 291
+ ++ DG+ R+ + +D G Y C A N +G A+ + + +
Sbjct: 5316 KIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQATYQVEILEHVEE 5375
Query: 292 ------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
P IN V G R +C P ++ W +G P + +
Sbjct: 5376 EKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG-----LPLRADSRTS 5430
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG----SSFVRGKLTVTS-DDDRPPPII 400
DG L IND+ + D C A N G S V K+ + P
Sbjct: 5431 IQYEEDGTATLAINDSTEEDI-GAYRCVATNAHGTINTSCSVNVKVPKQEVKKEGEEPFF 5489
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV---TNDG--TLVLK 455
T G + C P P I WY G+ L++N R V + DG +L +
Sbjct: 5490 TKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ-LLRNGPRTVIETSPDGSCSLTVN 5548
Query: 456 DLDKSDSGTYTCVASSRHGK 475
+ SD G Y C A + HGK
Sbjct: 5549 ESTMSDEGIYRCEAENAHGK 5568
Score = 92.7 bits (220), Expect = 1e-18
Identities = 126/525 (24%), Positives = 200/525 (38%), Gaps = 43/525 (8%)
Query: 33 CRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
C G P P + W + +H L G D GVY + N +G
Sbjct: 669 CEVEGWPEPELVWLVDDQ-PLRPSHDFRLQYDGQTAKLEIRDAQPDDTGVYTVKIQNEFG 727
Query: 93 TARSRNATLHVAV------LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
+ S+ A L V + EF+ E + +G+ V + + G P P + W NG
Sbjct: 728 SIESK-AELFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVIT-GDPNPEIIWFING 785
Query: 147 QTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLI 205
+ L + DG L I+D + G C N G+ S LK+ + P
Sbjct: 786 KPLSESEKVKFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSA-SCDGRLKVRVPPAPP 844
Query: 206 T--GP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR--VKVLD-DGSLRL 259
T P ED Q S+V F+ V G P P + + + G + G V+++ DG R+
Sbjct: 845 TFNKPLEDKTVQEKSTVVFEVDVSGWPEPTLTF--TLCGKELKNGEEGVEIVGHDGFYRI 902
Query: 260 D--NVIL-ADEGEYSCEAENSVGAVSASGYLTVYDP-------PSINLSPNSVNVESGNV 309
N + +GE +A+N G + LTV P+ V++G
Sbjct: 903 SIPNTSMDKHDGEIVAKAQNEHGTAESRARLTVEQEEEESRSAPTFLKDIEDQTVKTGEF 962
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
A F T G P P + W + G++ + G K A +T+ D T
Sbjct: 963 AVFETTVRGNPNPEVTWFINGHK--MDQGSPGVKIEAHNHDHKLTI------DSAQYAGT 1014
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDD-DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
++C A N G + +L V + + + PP ++T + + VF P+P
Sbjct: 1015 VLCRAENAVGRFETKARLVVLAPEKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPT 1074
Query: 429 IAWYFEGEALIQNHRRNVTN-DGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
+ WY +GE L Q+ R + DG+ + +K++ D+G VA++ G L V
Sbjct: 1075 VTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQ 1134
Query: 486 -SPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNK 529
P P R ++ G H T WS N +
Sbjct: 1135 KKPFAPEFD-LRPVSLTVEKGSEAVFSAHAFGIPLPTYEWSVNGR 1178
Score = 92.3 bits (219), Expect = 2e-18
Identities = 117/517 (22%), Positives = 201/517 (38%), Gaps = 69/517 (13%)
Query: 32 NCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRATHGRVHSDAGVYWCEATNS 90
N + G P+P +W+ G+ + D ++ A G + L R D G C A N
Sbjct: 5191 NVKVRGLPNPTFQWFLNGIPIKLDDRITLDDMADGNYCLTIRDVR-EEDFGTLKCIAKNE 5249
Query: 91 YGTARS----RNATLHVAVLREEFRLEPE------SKQSAQGDTVVLECLPPRGSPEPNV 140
GT + + H R++ R P ++ GD + +EC +P V
Sbjct: 5250 NGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVD-ANPTAEV 5308
Query: 141 YWKKNGQTLLFDGDSRM-HLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI 198
W K+G+ + + + + VDG + I ++D G Y C+A N G E+ AT ++
Sbjct: 5309 EWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQAETQ-ATYQV 5367
Query: 199 HIKPYL-----------ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
I ++ I P ED G + C+V P V+W + +PL
Sbjct: 5368 EILEHVEEEKRREYAPKINPPLEDKTVNGGQPIRLSCKVDAIPRASVVWYKDG----LPL 5423
Query: 247 GR-----VKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP------- 292
++ +DG+ L +++ D G Y C A N+ G ++ S + V P
Sbjct: 5424 RADSRTSIQYEEDGTATLAINDSTEEDIGAYRCVATNAHGTINTSCSVNVKVPKQEVKKE 5483
Query: 293 ---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
P + + G+ C TG P P + W G + R +
Sbjct: 5484 GEEPFFTKGLVDLWADRGDSFTLKCAVTGDPFPEIKWYRNGQ---LLRNGPRTVIETSP- 5539
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR---------GKLTVTSDDDRPPPII 400
DG LT+N++ +D C A N G + + GK D+ PP
Sbjct: 5540 -DGSCSLTVNESTMSDE-GIYRCEAENAHGKAKTQATAHVQMALGKTEKPKMDEGKPPKF 5597
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT-----LVLK 455
S+ ++ + ++ C P P + W +G LI++ R +N+ + L +K
Sbjct: 5598 ILELSDMSVSLGNVIDLECKVTGLPNPSVKWSKDGGPLIEDSRFEWSNEASKGVYQLRIK 5657
Query: 456 DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNI 492
+ D GTY CVA++ +G + +D + +
Sbjct: 5658 NATVHDEGTYRCVATNENGSATTKSFVRMDDGLGSGV 5694
Score = 90.2 bits (214), Expect = 8e-18
Identities = 118/480 (24%), Positives = 194/480 (40%), Gaps = 35/480 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + + G + L
Sbjct: 4400 PEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKNGKEIPNAKAKD--NGDGSYSLEI 4456
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLP 131
+ ++ D Y +N G A S +A L V + E + +G VL+
Sbjct: 4457 PNAQL-DDTADYKVVVSNDAGDADS-SAALTVKLPGIAIVKGLEDAEVPKGKKAVLQVET 4514
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAG- 187
+ E + W KNG+ + D DG N LVI DA DA Y+ + + G
Sbjct: 4515 NKKPKE--IKWYKNGKEIT-PSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGN 4571
Query: 188 TRESAIA-TLKIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG---GG 242
T +S+ A T+K+ K P +I G ED V GS + + G P V W ++ G
Sbjct: 4572 TADSSCALTVKLPAKEPKIIKGLEDQVVSIGSPIKLEIETSGSP-KTVKWYKNGKELPGA 4630
Query: 243 NMPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP- 299
+++ +DD L + + ++ D G+Y E N G+ ++SG +TV +P L P
Sbjct: 4631 AAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKITV-EPKITFLKPL 4689
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
++ G A F+ +P + W G I P ++ D L I
Sbjct: 4690 KDQSITEGENAEFSVETNTKPR-IVKWYKNGQE--IKP---NSRFIIEQKTDTKYQLVIK 4743
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
+ ++D+ +T N AG + +LTV I+ G +Q + + VF
Sbjct: 4744 NAVRDDA-DTYKIVLENTAGEAESSAQLTVKKAKAGLCKIV-KGLEDQVVAKGAKMVFEV 4801
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTN-DGT---LVLKDLDKSDSGTYTCVASSRHGK 475
PE + W + + + D T L++ D D+G YT + GK
Sbjct: 4802 KIQGEPED-VRWLRDANVISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGK 4860
Score = 89.0 bits (211), Expect = 2e-17
Identities = 126/494 (25%), Positives = 193/494 (39%), Gaps = 40/494 (8%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLF 67
GEAP ++ V V + A L + G P P+++WYK G L SD + G
Sbjct: 3917 GEAPDFLQPVKPVVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDGTQ 3976
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV---AVLREEFRLEPESKQSAQGDT 124
L T+ ++ D Y CEA+N +G S + TL V A + F E + Q + +T
Sbjct: 3977 RLTVTNAKL-DDMDEYRCEASNEFGDVWS-DVTLTVKEPAQVAPGFFKELSAIQVKETET 4034
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQCIA 182
EC +P+V W K+G L D D G LVI+D++ D G Y+
Sbjct: 4035 AKFEC--KVSGTKPDVKWFKDGTPLKEDKRVHFESTDDGTQRLVIEDSKTDDQGNYRIEV 4092
Query: 183 RNAAGTRESAIATLKIHIKPYLI-TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG- 240
N AG S + + + I G DV G+ + V G P V W +
Sbjct: 4093 SNDAGVANSKVPLTVVPSETLKIKKGLTDVNVTQGTKILLSVEVEGKP-KTVKWYKGTET 4151
Query: 241 -GGNMPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV------YDP 292
+ V+V + + L +++ ++D G Y +V +S +TV
Sbjct: 4152 VTSSQTTKIVQVTESEYKLEIESAEMSDTGAYRVVLSTDSFSVESSATVTVTKAAEKISL 4211
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
PS +V G G+P+ W G+ I G D + +G
Sbjct: 4212 PSFKKGLADQSVPKGTPLVLEVEIEGKPKDVK-WYKNGDE--IKDGKVED------LGNG 4262
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
LTI D + D V +A N AG + K+ V++ P I +G T+
Sbjct: 4263 KYRLTIPDFQEKDVGEYSV-TAANEAGEIESKAKVNVSA-----KPEIVSGLVPTTVKQG 4316
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG--TLVLKDLDKSDSGTYTCVAS 470
A F + P + WY G+ I + + DG +L + + D+ Y V S
Sbjct: 4317 ETATFN-VKVKGPVKGVKWYKNGKE-IPDAKTKDNGDGSYSLEIPNAQVEDAADYKVVVS 4374
Query: 471 SRHGKYVWSGALLV 484
+ G S AL V
Sbjct: 4375 NDAGDADSSAALTV 4388
Score = 89.0 bits (211), Expect = 2e-17
Identities = 111/474 (23%), Positives = 186/474 (39%), Gaps = 49/474 (10%)
Query: 38 SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
+P ++WYK + ++H G + A + D Y +N+ G S
Sbjct: 4898 APVRQVKWYKNDQEIKPNSHLEAKKIGPKKYELAINRAQLDDGADYKVVLSNAAGDCDSS 4957
Query: 98 NATLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
A V VL+ L+ + Q V L+ + G P+ + W KNGQ L D D
Sbjct: 4958 AALTVVKPNVLKIVDGLKDVDVEEPQ--PVELK-VKVEGIPKV-IKWYKNGQELKPDADG 5013
Query: 156 RM--HLVDGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGP--- 208
+ G +L I ++++D G Y+ + N G S +H+K + P
Sbjct: 5014 FKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGNDKGEVYSGSV---VHVKSAKSSEPTSG 5070
Query: 209 -------EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGSLR 258
+D + G +T QC + G+P P+V+W + + RV + +LR
Sbjct: 5071 ANFLSPLKDTEVEEGDMLTLQCTIAGEPFPEVIWEKDGVVLQKDDRITMRVALDGTATLR 5130
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV-NVESG-----NVARF 312
+ + +D G+Y A+N G+ ++ +TV + P V +++G + F
Sbjct: 5131 IRSPKKSDIGQYRVSAKNEAGSATSDCKVTVTEQGEQPSKPKFVIPLKTGAALPADKKEF 5190
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
G P PT W + G P D+ + DG LTI D + D T+ C
Sbjct: 5191 NVKVRGLPNPTFQWFLNG-----IPIKLDDRITLDDMADGNYCLTIRDVREEDF-GTLKC 5244
Query: 373 SAVNYAGSSFV-------RGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTP 425
A N G+ G + DD R PP ++ +P+ C P
Sbjct: 5245 IAKNENGTDETVCEFQQGAGHDDGSRDDLRYPPRFNVPLWDRRIPVGDPMFIECHVDANP 5304
Query: 426 EPIIAWYFEGEALIQNHRRNVTN--DGTLVLK--DLDKSDSGTYTCVASSRHGK 475
+ W+ +G+ + + N DG +K ++SD G Y CVA + G+
Sbjct: 5305 TAEVEWFKDGKKIEHTAHTEIRNTVDGACRIKIIPFEESDIGVYMCVAVNELGQ 5358
Score = 88.2 bits (209), Expect = 3e-17
Identities = 79/284 (27%), Positives = 116/284 (40%), Gaps = 10/284 (3%)
Query: 30 TLNCRA--GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
TL C+ G P+P ++WY G LV + I A G++ ++ HG G C A
Sbjct: 2579 TLECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMK-IHGVTADMTGKIKCVA 2637
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
N G + VA + EF +GDT+ L + G PEP V W NG+
Sbjct: 2638 YNKAGEVSTEGPLKVVAPIPVEFETSLCDATCREGDTLKLRAV-LLGEPEPVVSWYVNGK 2696
Query: 148 TLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIKPYL 204
L + ++H G + I+D +G+ C A N G T E+ + L P
Sbjct: 2697 KLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGEPPDF 2756
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDGSLRLDNVI 263
+ +V A+TG+ V + GDP P + W + N L + D S N
Sbjct: 2757 LEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTLTINSF 2816
Query: 264 LAD--EGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE 305
D GE C+AEN G VS + + Y + S + E
Sbjct: 2817 NPDVHVGEIICKAENDAGEVSCTANMITYTSDMFSESESEAQAE 2860
Score = 86.6 bits (205), Expect = 9e-17
Identities = 98/460 (21%), Positives = 167/460 (36%), Gaps = 28/460 (6%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P D V + G P P++ W G V + ++ G +
Sbjct: 2365 EVPKFTTNMDDRQVKEGEDVKFTANVEGYPEPSVAWTLNGEPVSKHPNITVTDKDGEHTI 2424
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVL 127
+ AG CEATN G+ + R+ L V + + F E + +G+ ++
Sbjct: 2425 EIS-AVTPEQAGELSCEATNPVGS-KKRDVQLAVKKVGDAPTFAKNLEDRLITEGELTLM 2482
Query: 128 ECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNA 185
+ P+P + W K+G + DG ++ + G+L + + D GR A +
Sbjct: 2483 DAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGSLKLSILQTKLEDKGRITIKAESE 2542
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSV--TFQCR--VGGDPLPDVLW----RR 237
G E + + + +P + +A + T +C+ + GDP P V W +
Sbjct: 2543 FGVAECSASLGVVKGRPMAKPAFQSDIAPINLTEGDTLECKLLITGDPTPFVKWYIGTQL 2602
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
+ + + ++++ V G+ C A N G VS G L V P +
Sbjct: 2603 VCATEDTEISNANGVY--TMKIHGVTADMTGKIKCVAYNKAGEVSTEGPLKVVAPIPVEF 2660
Query: 298 SPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
+ G+ + G PEP + W V G + K H+ G
Sbjct: 2661 ETSLCDATCREGDTLKLRAVLLGEPEPVVSWYVNGKK---LEESQNIKIHSEK---GTYT 2714
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
+TI D D +VC A+N G + L V + PP SN +
Sbjct: 2715 VTIKDITC-DYSGQVVCEAINEYGKATSEATLLVLPRGE--PPDFLEWLSNVRARTGTKV 2771
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHRRN-VTNDGTLVL 454
V P+P + WY + ++ + VT+D T L
Sbjct: 2772 VHKVVFTGDPKPSLTWYINNKEILNSDLYTIVTDDKTSTL 2811
Score = 85.0 bits (201), Expect = 3e-16
Identities = 80/296 (27%), Positives = 130/296 (43%), Gaps = 31/296 (10%)
Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAG-GLFFLRATHG 74
+PL+V + L G+P P + W+K + + ++H G G L
Sbjct: 3489 RPLEVR--EQETLDLKVTVIGTPVPNVEWFKDDKPINIDNSHIFGKDEGSGHHTLTIKQA 3546
Query: 75 RVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPR 133
R D GVY C+ATN G A++ N + + F + + QG L +
Sbjct: 3547 R-GEDVGVYTCKATNEAGEAKTTANMAVQEEIEAPLFVQGLKPYEVEQGKPAEL-VVRVE 3604
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD--GGN----LVIQDARQTDAGRYQCIARNAAG 187
G PEP V W K+G + D H+++ G N LVI+D D G+Y C A N AG
Sbjct: 3605 GKPEPEVKWFKDGVPIAIDNQ---HVIEKKGENGSHTLVIKDTNNADFGKYTCQATNKAG 3661
Query: 188 TRESAIATLKI-----------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
++ + LKI +KP I ++ A G +V +C+V + P + +
Sbjct: 3662 -KDETVGELKIPKYSFEKQTAEEVKPLFIEPLKETFAVEGDTVVLECKVNKESHPQIKFF 3720
Query: 237 RSAGGGNMPLG-RVKVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ + +++VL+DG+++L N D G Y CEA N G + + L +
Sbjct: 3721 KNDQPVEIGQHMQLEVLEDGNIKLTIQNAKKEDVGAYRCEAVNVAGKANTNADLKI 3776
Score = 80.6 bits (190), Expect = 6e-15
Identities = 102/403 (25%), Positives = 167/403 (41%), Gaps = 33/403 (8%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAG-GSPSPAIRWYKGGVLVVSDTHRSILPA-GGL 66
G+AP + D + + ++ + P P I W K GV + SD H I+ G
Sbjct: 2460 GDAPTFAKNLEDRLITEGELTLMDAKLNIVKPKPKITWLKDGVEITSDGHYKIVEEEDGS 2519
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVA----VLREEFRLEPESKQSAQG 122
L ++ D G +A + +G A +A+L V + + F+ + +G
Sbjct: 2520 LKLSILQTKLE-DKGRITIKAESEFGVAEC-SASLGVVKGRPMAKPAFQSDIAPINLTEG 2577
Query: 123 DTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQC 180
DT LEC L G P P V W Q + D+ + +G + I G+ +C
Sbjct: 2578 DT--LECKLLITGDPTPFVKWYIGTQLVCATEDTEISNANGVYTMKIHGVTADMTGKIKC 2635
Query: 181 IARNAAGTRESAIATLKIHIKPYLI---TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+A N AG S LK+ + P + T D + G ++ + + G+P P V W
Sbjct: 2636 VAYNKAG-EVSTEGPLKV-VAPIPVEFETSLCDATCREGDTLKLRAVLLGEPEPVVSWYV 2693
Query: 238 SAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---D 291
+ G +K+ + ++ + ++ G+ CEA N G ++ L V +
Sbjct: 2694 N-GKKLEESQNIKIHSEKGTYTVTIKDITCDYSGQVVCEAINEYGKATSEATLLVLPRGE 2752
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP ++V +G TG P+P++ W + N+ I+ + D Y T V D
Sbjct: 2753 PPDFLEWLSNVRARTGTKVVHKVVFTGDPKPSLTWYIN-NKEIL----NSDLY--TIVTD 2805
Query: 352 GVT-VLTINDTDKNDSRNTIVCSAVNYAGS-SFVRGKLTVTSD 392
T LTIN + + I+C A N AG S +T TSD
Sbjct: 2806 DKTSTLTINSFNPDVHVGEIICKAENDAGEVSCTANMITYTSD 2848
Score = 77.8 bits (183), Expect = 4e-14
Identities = 119/486 (24%), Positives = 189/486 (38%), Gaps = 39/486 (8%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
D +V + P L G P ++WYK G + + G + L + D
Sbjct: 4220 DQSVPKGTPLVLEVEIEGKPKD-VKWYKNGDEIKDGKVEDL--GNGKYRLTIPDFQ-EKD 4275
Query: 80 AGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESKQSAQGDTVVLECLPPRGSPEP 138
G Y A N G S+ A ++V+ E L P + + QG+T + +G P
Sbjct: 4276 VGEYSVTAANEAGEIESK-AKVNVSAKPEIVSGLVPTTVK--QGETATFN-VKVKG-PVK 4330
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIA-TLK 197
V W KNG+ + D ++ + +L I +A+ DA Y+ + N AG +S+ A T+K
Sbjct: 4331 GVKWYKNGKEIP-DAKTKDNGDGSYSLEIPNAQVEDAADYKVVVSNDAGDADSSAALTVK 4389
Query: 198 I------HIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
+ +KP +++G + G + TF +V G P+ V W ++ G +P + K
Sbjct: 4390 LADDGKDKVKPEIVSGLIPTTVKQGETATFNVKVKG-PVKQVKWYKN--GKEIPNAKAKD 4446
Query: 252 LDDG--SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP-SINLSPNSVNVESGN 308
DG SL + N L D +Y N G +S LTV P +I V G
Sbjct: 4447 NGDGSYSLEIPNAQLDDTADYKVVVSNDAGDADSSAALTVKLPGIAIVKGLEDAEVPKGK 4506
Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
A +P+ + W G I P DK + D L I D +D+
Sbjct: 4507 KAVLQVETNKKPK-EIKWYKNGKE--ITPS---DKAQPGSDGDNKPQLVIPDAGDDDAAE 4560
Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPI 428
V ++ LTV P I G +Q + I S +P+
Sbjct: 4561 YKVVLTDEDGNTADSSCALTVKLPAKEPK--IIKGLEDQVVSIGSPIKLEIETSGSPK-T 4617
Query: 429 IAWYFEGEALIQNHRRNV----TNDGTLVLKDLDK--SDSGTYTCVASSRHGKYVWSGAL 482
+ WY G+ L + + +D VL+ D+G Y ++ G SG +
Sbjct: 4618 VKWYKNGKELPGAAAKTIKIQKIDDNKYVLEIPSSVVEDTGDYKVEVANEAGSANSSGKI 4677
Query: 483 LVDSPI 488
V+ I
Sbjct: 4678 TVEPKI 4683
Score = 75.4 bits (177), Expect = 2e-13
Identities = 74/289 (25%), Positives = 114/289 (39%), Gaps = 23/289 (7%)
Query: 217 SSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DG--SLRLDNVILADEGEYSCE 273
SS +V G PLPD+ W + + D DG ++ +D V + D G Y+C
Sbjct: 563 SSAKMCLKVTGYPLPDITWYKDDVQLHEDERHTFYSDEDGFFAMTIDPVQVTDTGRYTCM 622
Query: 274 AENSVGAVSASGYLTVYD------PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWS 327
A N G S S + V PP+ + G+V F C G PEP + W
Sbjct: 623 ATNEYGQASTSAFFRVLKVEKEAAPPAFVTKLRDKECKEGDVIDFECEVEGWPEPELVWL 682
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTV-LTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
V+ R + +DG T L I D +D+ N GS + +
Sbjct: 683 VDDQPL-------RPSHDFRLQYDGQTAKLEIRDAQPDDT-GVYTVKIQNEFGSIESKAE 734
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICT--PEPIIAWYFEGEALIQNHR- 443
L V +D D+ + + + ++ T P P I W+ G+ L ++ +
Sbjct: 735 LFVQADPDKNHVAPEFQATIEYVECDEGEEVRFKSVITGDPNPEIIWFINGKPLSESEKV 794
Query: 444 RNVTNDG--TLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINP 490
+ ++ DG L +KD+ + G TC S+R G G L V P P
Sbjct: 795 KFISEDGICILTIKDVTRHFDGMVTCQGSNRLGSASCDGRLKVRVPPAP 843
Score = 74.5 bits (175), Expect = 4e-13
Identities = 119/491 (24%), Positives = 192/491 (39%), Gaps = 40/491 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--PAGGLFFL 69
P II+ D V+ P L GSP ++WYK G + ++I ++
Sbjct: 4588 PKIIKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKELPGAAAKTIKIQKIDDNKYV 4646
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQS-AQGDTVVLE 128
V D G Y E N G+A N++ + V + L+P QS +G+ E
Sbjct: 4647 LEIPSSVVEDTGDYKVEVANEAGSA---NSSGKITVEPKITFLKPLKDQSITEGENA--E 4701
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQDARQTDAGRYQCIARN 184
+ V W KNGQ + +SR + + LVI++A + DA Y+ + N
Sbjct: 4702 FSVETNTKPRIVKWYKNGQEI--KPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759
Query: 185 AAGTRESAIATLKIHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
AG ES+ K L + G ED V G+ + F+ ++ G+P DV W R A
Sbjct: 4760 TAGEAESSAQLTVKKAKAGLCKIVKGLEDQVVAKGAKMVFEVKIQGEP-EDVRWLRDANV 4818
Query: 242 GNMPLGRV-KVLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
+ + + +DD + RL + L D GEY+ E N G + V + P I
Sbjct: 4819 ISAGANAIIEKIDDTTYRLIIPSADLKDAGEYTVEVINESGKAKSDAKGEVDEKPEIVRG 4878
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
++ + G+ F + P + W N I P A + L I
Sbjct: 4879 LENIEIPEGDDDVFKVEVSA-PVRQVKW--YKNDQEIKP---NSHLEAKKIGPKKYELAI 4932
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFP 418
N +D + V + N AG LTV + I +G + +
Sbjct: 4933 NRAQLDDGADYKVVLS-NAAGDCDSSAALTVVKPNVLK---IVDGLKDVDVEEPQPVELK 4988
Query: 419 CTAICTPEPIIAWYFEGEAL------IQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
P+ +I WY G+ L + + + + +L + KSD G Y V +
Sbjct: 4989 VKVEGIPK-VIKWYKNGQELKPDADGFKFEEKPESGEFSLTIPSSKKSDGGAYRVVLGND 5047
Query: 473 HGKYVWSGALL 483
G+ V+SG+++
Sbjct: 5048 KGE-VYSGSVV 5057
Score = 74.5 bits (175), Expect = 4e-13
Identities = 99/334 (29%), Positives = 140/334 (41%), Gaps = 50/334 (14%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARH-QPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSI 60
D + G+AP PL + A+ T C G+P P+I+W K G+ + SD +
Sbjct: 5916 DSSIREGKAPGFTT-PLTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKME 5974
Query: 61 LPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-------EEFRLE 113
A G L + S+ G + C ATN +GTA S A L + R E E
Sbjct: 5975 AAADGTQRLILSDVTFLSE-GYFRCVATNEHGTA-STKAELVIEGDRTIGSRPLPEVNGE 6032
Query: 114 PES----------KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--- 160
PE S VV + G P P V W K+GQ ++ DG ++
Sbjct: 6033 PEECKPRIRRGLYNMSIHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTD 6092
Query: 161 DGG--NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG---------PE 209
+ G +LVI +A D G Y A N G+ ++ +L I I+P I P
Sbjct: 6093 ERGIHHLVIVNASPDDEGEYSLEATNKLGSAKTE-GSLNI-IRPRHIADADERGGMPFPP 6150
Query: 210 DVVAQTGSS-------VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG----SLR 258
V Q + F C V G P P+V W + G +P GR+K+ G +L
Sbjct: 6151 GFVRQLKNKHVFNHMPTIFDCLVVGHPGPEVEWFHN-GKKIVPGGRIKIQSCGGGSHALI 6209
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDP 292
+ + L D GEY A+NS G+ S+S L V P
Sbjct: 6210 ILDTTLEDAGEYVATAKNSHGSASSSAVLDVTVP 6243
Score = 72.5 bits (170), Expect = 2e-12
Identities = 87/393 (22%), Positives = 159/393 (40%), Gaps = 30/393 (7%)
Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
V+ +F + + ++ +G + V EC+ P + W K+G+ + R+ G
Sbjct: 2884 VMAPKFITKIKDTKAKKGHSAVFECVVP-DTKGVCCKWLKDGKEIELIARIRVQTRTGPE 2942
Query: 165 ------LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKIHIK------PYLITGPED 210
LV+ + DAG+Y CI N AG T E+ + ++ K P I +D
Sbjct: 2943 GHITQELVLDNVTPEDAGKYTCIVENTAGKDTCEATLTVIESLEKKSEKKAPEFIVALQD 3002
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDD-GSLRLDNVILADEGE 269
+T V +C+V G+P P V W V+ ++ + + + L+ +G+
Sbjct: 3003 KTTKTSEKVVLECKVIGEPKPKVSWLHDNKTITQESITVESVEGVERVTITSSELSHQGK 3062
Query: 270 YSCEAENSVGAVSASGYLTVY-DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
Y+C AEN+ G +LTV + P + + G +C+ G P+P + +
Sbjct: 3063 YTCIAENTEGTSKTEAFLTVQGEAPVFTKELQNKELSIGEKLVLSCSVKGSPQPHVDFYS 3122
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVT--VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
T + ++ A T + I+ K D + A N G++ K
Sbjct: 3123 FSETTKVETKITSSSRIAIEHDQTNTHWRMVISQITKEDI-VSYKAIATNSIGTATSTSK 3181
Query: 387 LTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ--NH-- 442
+T + P+ G ++ K + P + W+ + + + + NH
Sbjct: 3182 ITTKVE----APVFEQGLKKTSVKEKEEIKME-VKVGGSAPDVEWFKDDKPVSEDGNHEM 3236
Query: 443 RRN-VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
++N T TLV+K +D+G YT AS+ G
Sbjct: 3237 KKNPETGVFTLVVKQAATTDAGKYTAKASNPAG 3269
Score = 72.5 bits (170), Expect = 2e-12
Identities = 119/493 (24%), Positives = 193/493 (39%), Gaps = 42/493 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ + TV + + AT N + G P ++WYK G + + G + L
Sbjct: 4302 PEIVSGLVPTTVKQGETATFNVKVKG-PVKGVKWYKNGKEIPDAKTKD--NGDGSYSLEI 4358
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSA------QGDT 124
+ +V DA Y +N G A S +A L V + + + +++PE QG+T
Sbjct: 4359 PNAQVE-DAADYKVVVSNDAGDADS-SAALTVKLADDGKDKVKPEIVSGLIPTTVKQGET 4416
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+ +G P V W KNG+ + + ++ + +L I +A+ D Y+ + N
Sbjct: 4417 ATFN-VKVKG-PVKQVKWYKNGKEIP-NAKAKDNGDGSYSLEIPNAQLDDTADYKVVVSN 4473
Query: 185 AAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
AG +S+ A T+K+ ++ G ED G Q P ++ W ++ G
Sbjct: 4474 DAGDADSSAALTVKLP-GIAIVKGLEDAEVPKGKKAVLQVETNKKP-KEIKWYKN-GKEI 4530
Query: 244 MPLGRVKVLDDGSLRLDNVILA----DEGEYSCEAENSVG-AVSASGYLTVYDP---PSI 295
P + + DG + VI D EY + G +S LTV P P I
Sbjct: 4531 TPSDKAQPGSDGDNKPQLVIPDAGDDDAAEYKVVLTDEDGNTADSSCALTVKLPAKEPKI 4590
Query: 296 NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTV 355
V G+ + +G P+ T+ W G PG + + D V
Sbjct: 4591 IKGLEDQVVSIGSPIKLEIETSGSPK-TVKWYKNGKE---LPGAAAKTIKIQKIDDNKYV 4646
Query: 356 LTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMA 415
L I + D+ + V N AGS+ GK+TV P +Q++ A
Sbjct: 4647 LEIPSSVVEDTGDYKV-EVANEAGSANSSGKITV-----EPKITFLKPLKDQSITEGENA 4700
Query: 416 VFPCTAICTPEPIIAWYFEGEALIQNHR----RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
F P I+ WY G+ + N R + LV+K+ + D+ TY V +
Sbjct: 4701 EFSVETNTKPR-IVKWYKNGQEIKPNSRFIIEQKTDTKYQLVIKNAVRDDADTYKIVLEN 4759
Query: 472 RHGKYVWSGALLV 484
G+ S L V
Sbjct: 4760 TAGEAESSAQLTV 4772
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 15/207 (7%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG---QTLLFDGDSRMHLVDGGN--LVIQD 169
E + A+ DT+ + L G P+P++ WK G T +++ G L I
Sbjct: 6417 EKRYCAENDTLTI-VLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITG 6475
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
+ + G+YQC A+N G + I + + +P I + + + RV G+P
Sbjct: 6476 FSKENVGQYQCFAKNDYGDAQQNIM-VDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEP 6534
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P++ W + + R+K + DG SL +++ + D G YSC A N G + S
Sbjct: 6535 FPELKWMKE-WRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 6593
Query: 286 YLTVY---DPPSINLSPNSVNVESGNV 309
+TV D + L V +ES V
Sbjct: 6594 TVTVEAEGDYNDVELPRRRVTIESRRV 6620
Score = 64.1 bits (149), Expect = 6e-10
Identities = 94/423 (22%), Positives = 157/423 (37%), Gaps = 33/423 (7%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
S AP ++ D TV + A G+P+P + W+ G + + + A
Sbjct: 942 SRSAPTFLKDIEDQTVKTGEFAVFETTVRGNPNPEVTWFINGHKMDQGSPGVKIEAHNHD 1001
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE-------SKQSA 120
+ AG C A N+ G ++ + VL E + +P K
Sbjct: 1002 HKLTIDSAQY--AGTVLCRAENAVGRFETK---ARLVVLAPEKQKKPPKFVEILVDKTET 1056
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQ 179
+TVV E + G P+P V W G+ L + DG + I++ + DAG +
Sbjct: 1057 VDNTVVFE-VRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDAGEIR 1115
Query: 180 CIARNAAGTRESAIATLKIHIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
+A N+ G+ E+ A L + KP+ P + + GS F G PLP W
Sbjct: 1116 AVATNSEGSDETK-AKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPTYEWS 1174
Query: 237 RSA-----GGGNMPLGRVKVLDDGS--LRLDNVILADEGEY---SCEAENSVGAVSASGY 286
+ G + R + DG+ L +D E + S AEN++GA
Sbjct: 1175 VNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEETGAQ 1234
Query: 287 LTVYDPPSINLSPNSVNVESGNVARFTC--TATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
LT+ +P ++ ++ S V + PE T ++E + T +
Sbjct: 1235 LTI-EPKKESVVVEKQDLSSSEVQKEIAQQVKEASPEATTTITMETSLTST-KTTTMSTT 1292
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGP 404
T+ GVTV T +++ + I + S K+ V S D + P
Sbjct: 1293 EVTSTVGGVTVET-KESESESATTVIGGGSGGVTEGSISVSKIEVVSKTDSQTDVREGTP 1351
Query: 405 SNQ 407
+
Sbjct: 1352 KRR 1354
Score = 62.1 bits (144), Expect = 2e-09
Identities = 68/257 (26%), Positives = 91/257 (35%), Gaps = 16/257 (6%)
Query: 277 SVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIF 336
+VG ++S T P S V A C G P P + W+ EG
Sbjct: 3801 TVGDTASSKTDTGRGAPEFVELLRSCTVTEKQQAILKCKVKGEPRPKIKWTKEGKEV--- 3857
Query: 337 PGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD--- 393
MS + A DG LT D R I C A N GS++ G + VT +
Sbjct: 3858 -EMSA-RVRAEHKDDGTLTLTF-DNVTQARRRRIRCEAENEYGSAWTEGPIIVTLEGAPK 3914
Query: 394 -DRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DG 450
D P + + AV P+P + WY GE L + R + N DG
Sbjct: 3915 IDGEAPDFLQPVKPVVVTVGETAVLEGKISGKPKPSVKWYKNGEELKPSDRVKIENLDDG 3974
Query: 451 T--LVLKDLDKSDSGTYTCVASSRHGKYVWSG-ALLVDSPINPNIHFFRAADVSSLPGPP 507
T L + + D Y C AS+ G VWS L V P FF+ +
Sbjct: 3975 TQRLTVTNAKLDDMDEYRCEASNEFGD-VWSDVTLTVKEPAQVAPGFFKELSAIQVKETE 4033
Query: 508 TKPITHNVTDTSVTLSW 524
T V+ T + W
Sbjct: 4034 TAKFECKVSGTKPDVKW 4050
Score = 56.4 bits (130), Expect = 1e-07
Identities = 88/376 (23%), Positives = 148/376 (39%), Gaps = 27/376 (7%)
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
D +G +A NAAG+ E+ LK+ P PE VT V D
Sbjct: 1944 DTTMFGSGTVSVVASNAAGSVETK-TELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMD 2002
Query: 229 --PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVGAVSA 283
L L++ G + G+ V ++I+ D G+ + EA N VG+ +
Sbjct: 2003 VIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSES 2062
Query: 284 SGYLTVYDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
S LTV P P + P SV ++ A F T +G P PT+ W++ N I+
Sbjct: 2063 SAQLTVNPPSTTPIVVDGPKSVTIKETETAEFKATISGFPAPTVKWTI--NEKIV----E 2116
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP--PP 398
+ T + V L I++ K + T+ +A N AG + L V + P
Sbjct: 2117 ESRTITTIKTEDVYTLKISN-PKIEQTGTVKVTAQNSAGQDSKQADLKVEPNVKAPKFKS 2175
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN--DGT--LVL 454
+T+ +++ P++ +P ++W G+ L ++ V + DGT + +
Sbjct: 2176 QLTDKVADEGEPLRWNLELDGP---SPGTEVSWLLNGQPLTKSDTVQVVDHGDGTYHVTI 2232
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHN 514
+ SGT T + G+ S + V+ N F +A + +
Sbjct: 2233 AEAKPEMSGTLTPKPKNAAGECETSPKVTVNGG-NKKPEFVQAPQNHETTLEGSVKFSAI 2291
Query: 515 VTDTSV-TLSWSQNNK 529
VT + ++W NNK
Sbjct: 2292 VTGKPIPNVTWYLNNK 2307
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 12/171 (7%)
Query: 24 ARHQPATLNCRAGGSPSPAIRW-YKG-GVLVVSDTHR-SILPAGGLFFLRATHGRVHSDA 80
A + T+ G P P I+W ++G + S T + + GG A G +
Sbjct: 6422 AENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENV 6481
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N YG A+ +N + +A R F ++P ++ + + G P P +
Sbjct: 6482 GQYQCFAKNDYGDAQ-QNIMVDLAT-RPNF-IQPLVNKTFSSAQPMRMDVRVDGEPFPEL 6538
Query: 141 YWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG 187
W K + ++ SR+ V G +L+I D D+G Y C+A N AG
Sbjct: 6539 KWMKEWRPIV--ESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAG 6587
Score = 39.9 bits (89), Expect = 0.011
Identities = 21/83 (25%), Positives = 36/83 (43%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ ++ T + QP ++ R G P P ++W K +V + + G
Sbjct: 6507 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 6566
Query: 72 THGRVHSDAGVYWCEATNSYGTA 94
+ + D+G+Y C A N G A
Sbjct: 6567 INDPMWRDSGIYSCVAVNDAGQA 6589
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P P + W E ++++ R DG +L++ D DSG Y+CVA + G+ S
Sbjct: 6534 PFPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 6593
Query: 481 ALLVDS 486
+ V++
Sbjct: 6594 TVTVEA 6599
>U80438-4|AAB37634.2| 1415|Caenorhabditis elegans Uncoordinated
protein 40 protein.
Length = 1415
Score = 118 bits (284), Expect = 3e-26
Identities = 175/745 (23%), Positives = 293/745 (39%), Gaps = 91/745 (12%)
Query: 109 EFRLEPESKQSA-QGDTVVLEC----LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163
+F +EP + + + +LEC R + + WK++G L SR+ ++ G
Sbjct: 42 QFVMEPRRNVTVMESSSHLLECSYVLAHERLVHDVRIEWKRDGVLLSERTSSRIKVMSNG 101
Query: 164 NLVIQDARQTDAGRYQC---IARNAAGTRE-----SAIATLKI-HIKPYLITGPEDVVAQ 214
+L I+ + G YQC + + T + S ATL++ + + + + +A+
Sbjct: 102 SLWIESVSSAEEGTYQCAVHVTTKSDQTSDTWTFLSRKATLRLADLAKFELQAIDRTLAK 161
Query: 215 TGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270
G F C + P P +W + GG + V +L + + EG Y
Sbjct: 162 -GQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPV----SNTLEISSTQSRHEGTY 216
Query: 271 SCEAENS-VGAVSASGYLTVYDPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTM 324
C E + S + LTV N +P VE G+ C P +
Sbjct: 217 RCTVEGAGKRRSSQTARLTVTTETVSNELVFITTPRLQVVEQGDEFLLECLVASLIRPQV 276
Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
W ++ +R II G+ + +++ V+ +I DT C A N S R
Sbjct: 277 RW-LKDSRQIIVDGVRIRRVGVSSIL--VSRASIEDT------GLYTCRASN-NDDSIDR 326
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHR 443
S + R PP IT P+ + + C TA PE + WY GEA+I
Sbjct: 327 ----AVSVEVRAPPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKNGEAII-GSE 381
Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503
V L + + ++D Y C+A + G S LLVD+P + ++ A S +
Sbjct: 382 YFVIEPNRLRILGVVRADQAIYQCIAENDVGSEQASAQLLVDAPDSSSV-----AASSGV 436
Query: 504 PGPPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
P + P+ T + + + W + + +I+ Y +F ++ L NS
Sbjct: 437 PMTSSAPLGLRSTSSGSRFINVEWDPPVQ-RNGNIMRY--HIFYKDNLIDRERMINS--- 490
Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGV 620
T + SL P Y+ V EN G+ SDS+ V + G
Sbjct: 491 -------SSTSATLTSLQPSTMYLIRVTAENEAGM---GKFSDSLKVTTNKEQAVPGKVA 540
Query: 621 SNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEM 680
S +T D I +P L ++I FY + PL+ + E
Sbjct: 541 SLTTTATGPETID-----IRWSPPSGGQPALRYKI--FYSHD-------PLE----KNEK 582
Query: 681 KTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEM 740
+T++ + + + + + KYT Y+ + G S++ +T D P PP+NI+
Sbjct: 583 ETLI-TTSTTHYTLHGMDKYTGYQIRIEAEGSNGSGLSSDTVKVRTQSDEPSAPPVNIQA 641
Query: 741 FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800
++T+V + W PE + NG ITGY + A + + I+ T + T M NL
Sbjct: 642 EADSSTSVRVSWDEPEEESVNGEITGYRLKYKTKARGAKGNTLVIDATAREYT---MGNL 698
Query: 801 TSGVSYSVQIAAETIIGLGPFSQKV 825
Y +++A G GPFS V
Sbjct: 699 EPNTQYLIRMAVVNHNGTGPFSDWV 723
Score = 101 bits (243), Expect = 2e-21
Identities = 80/291 (27%), Positives = 129/291 (44%), Gaps = 15/291 (5%)
Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
Q +D T+A+ QP +C P+P W +V+ ILP + +T R
Sbjct: 153 QAIDRTLAKGQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPVSNTLEISSTQSR- 211
Query: 77 HSDAGVYWC--EATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVLECLPP 132
H G Y C E ++++ T+ + E F P + QGD +LECL
Sbjct: 212 HE--GTYRCTVEGAGKRRSSQTARLTVTTETVSNELVFITTPRLQVVEQGDEFLLECLVA 269
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
P V W K+ + ++ DG R+ V ++++ A D G Y C A N + + A
Sbjct: 270 -SLIRPQVRWLKDSRQIIVDG-VRIRRVGVSSILVSRASIEDTGLYTCRASNNDDSIDRA 327
Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQC-RVGGDPLPDVLWRRSAGGGNMPLG-RVK 250
++ +++ P + T P VA + V +C P V W ++ G +G
Sbjct: 328 VS-VEVRAPPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKN---GEAIIGSEYF 383
Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
V++ LR+ V+ AD+ Y C AEN VG+ AS L V P S +++ +S
Sbjct: 384 VIEPNRLRILGVVRADQAIYQCIAENDVGSEQASAQLLVDAPDSSSVAASS 434
Score = 35.9 bits (79), Expect = 0.18
Identities = 46/169 (27%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVA---QTLDDVPDGPPINIEMFILNTTTVH- 749
+ LR T+YEF + G+ S +A +TL P P ++ + + H
Sbjct: 906 VEGLRPATEYEFAVRAVASN--GQLSTWSMATRNRTLAAPPSSAPRDLTVLPAESGDPHS 963
Query: 750 --LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807
L W PP+ NG I Y V A+K IN S ++NL +Y
Sbjct: 964 SSLHWQPPKYS--NGEIEEYLVFYTDRASLADKDWT-INYVAGDKLSHQVSNLLPKANYF 1020
Query: 808 VQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFV 856
+I A G GPFS V + ++ L R+ G S +GD V
Sbjct: 1021 FKIQARNEKGHGPFSSVVGYTPSGGAI-LSGKDRHNARGHGSAASGDTV 1068
>U70618-1|AAB17088.1| 1415|Caenorhabditis elegans unc-40 protein.
Length = 1415
Score = 118 bits (284), Expect = 3e-26
Identities = 175/745 (23%), Positives = 293/745 (39%), Gaps = 91/745 (12%)
Query: 109 EFRLEPESKQSA-QGDTVVLEC----LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163
+F +EP + + + +LEC R + + WK++G L SR+ ++ G
Sbjct: 42 QFVMEPRRNVTVMESSSHLLECSYVLAHERLVHDVRIEWKRDGVLLSERTSSRIKVMSNG 101
Query: 164 NLVIQDARQTDAGRYQC---IARNAAGTRE-----SAIATLKI-HIKPYLITGPEDVVAQ 214
+L I+ + G YQC + + T + S ATL++ + + + + +A+
Sbjct: 102 SLWIESVSSAEEGTYQCAVHVTTKSDQTSDTWTFLSRKATLRLADLAKFELQAIDRTLAK 161
Query: 215 TGSSVTFQCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270
G F C + P P +W + GG + V +L + + EG Y
Sbjct: 162 -GQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPV----SNTLEISSTQSRHEGTY 216
Query: 271 SCEAENS-VGAVSASGYLTVYDPPSIN-----LSPNSVNVESGNVARFTCTATGRPEPTM 324
C E + S + LTV N +P VE G+ C P +
Sbjct: 217 RCTVEGAGKRRSSQTARLTVTTETVSNELVFITTPRLQVVEQGDEFLLECLVASLIRPQV 276
Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
W ++ +R II G+ + +++ V+ +I DT C A N S R
Sbjct: 277 RW-LKDSRQIIVDGVRIRRVGVSSIL--VSRASIEDT------GLYTCRASN-NDDSIDR 326
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALIQNHR 443
S + R PP IT P+ + + C TA PE + WY GEA+I
Sbjct: 327 ----AVSVEVRAPPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKNGEAII-GSE 381
Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSL 503
V L + + ++D Y C+A + G S LLVD+P + ++ A S +
Sbjct: 382 YFVIEPNRLRILGVVRADQAIYQCIAENDVGSEQASAQLLVDAPDSSSV-----AASSGV 436
Query: 504 PGPPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGW 560
P + P+ T + + + W + + +I+ Y +F ++ L NS
Sbjct: 437 PMTSSAPLGLRSTSSGSRFINVEWDPPVQ-RNGNIMRY--HIFYKDNLIDRERMINS--- 490
Query: 561 VVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGV 620
T + SL P Y+ V EN G+ SDS+ V + G
Sbjct: 491 -------SSTSATLTSLQPSTMYLIRVTAENEAGM---GKFSDSLKVTTNKEQAVPGKVA 540
Query: 621 SNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEM 680
S +T D I +P L ++I FY + PL+ + E
Sbjct: 541 SLTTTATGPETID-----IRWSPPSGGQPALRYKI--FYSHD-------PLE----KNEK 582
Query: 681 KTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEM 740
+T++ + + + + + KYT Y+ + G S++ +T D P PP+NI+
Sbjct: 583 ETLI-TTSTTHYTLHGMDKYTGYQIRIEAEGSNGSGLSSDTVKVRTQSDEPSAPPVNIQA 641
Query: 741 FILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNL 800
++T+V + W PE + NG ITGY + A + + I+ T + T M NL
Sbjct: 642 EADSSTSVRVSWDEPEEESVNGEITGYRLKYKTKARGAKGNTLVIDATAREYT---MGNL 698
Query: 801 TSGVSYSVQIAAETIIGLGPFSQKV 825
Y +++A G GPFS V
Sbjct: 699 EPNTQYLIRMAVVNHNGTGPFSDWV 723
Score = 101 bits (243), Expect = 2e-21
Identities = 80/291 (27%), Positives = 129/291 (44%), Gaps = 15/291 (5%)
Query: 17 QPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV 76
Q +D T+A+ QP +C P+P W +V+ ILP + +T R
Sbjct: 153 QAIDRTLAKGQPTAFHCLINSKPTPTAVWLHNDEPIVNGGEYHILPVSNTLEISSTQSR- 211
Query: 77 HSDAGVYWC--EATNSYGTARSRNATLHVAVLREE--FRLEPESKQSAQGDTVVLECLPP 132
H G Y C E ++++ T+ + E F P + QGD +LECL
Sbjct: 212 HE--GTYRCTVEGAGKRRSSQTARLTVTTETVSNELVFITTPRLQVVEQGDEFLLECLVA 269
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
P V W K+ + ++ DG R+ V ++++ A D G Y C A N + + A
Sbjct: 270 -SLIRPQVRWLKDSRQIIVDG-VRIRRVGVSSILVSRASIEDTGLYTCRASNNDDSIDRA 327
Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQC-RVGGDPLPDVLWRRSAGGGNMPLG-RVK 250
++ +++ P + T P VA + V +C P V W ++ G +G
Sbjct: 328 VS-VEVRAPPRITTRPTTKVAVETADVELECGTAAARPEARVNWYKN---GEAIIGSEYF 383
Query: 251 VLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
V++ LR+ V+ AD+ Y C AEN VG+ AS L V P S +++ +S
Sbjct: 384 VIEPNRLRILGVVRADQAIYQCIAENDVGSEQASAQLLVDAPDSSSVAASS 434
Score = 35.9 bits (79), Expect = 0.18
Identities = 46/169 (27%), Positives = 67/169 (39%), Gaps = 12/169 (7%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVA---QTLDDVPDGPPINIEMFILNTTTVH- 749
+ LR T+YEF + G+ S +A +TL P P ++ + + H
Sbjct: 906 VEGLRPATEYEFAVRAVASN--GQLSTWSMATRNRTLAAPPSSAPRDLTVLPAESGDPHS 963
Query: 750 --LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYS 807
L W PP+ NG I Y V A+K IN S ++NL +Y
Sbjct: 964 SSLHWQPPKYS--NGEIEEYLVFYTDRASLADKDWT-INYVAGDKLSHQVSNLLPKANYF 1020
Query: 808 VQIAAETIIGLGPFSQKVYFNIDSRSVGLDLLSRYPMNGEVSIVAGDFV 856
+I A G GPFS V + ++ L R+ G S +GD V
Sbjct: 1021 FKIQARNEKGHGPFSSVVGYTPSGGAI-LSGKDRHNARGHGSAASGDTV 1068
>AF456361-1|AAL60232.1| 1187|Caenorhabditis elegans immunoglobulin
domain-containingprotein Y54G2A.25 protein.
Length = 1187
Score = 111 bits (266), Expect = 4e-24
Identities = 112/477 (23%), Positives = 194/477 (40%), Gaps = 53/477 (11%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP----AGGLFFLRATHGRVHSDAGVYWC 85
TL C A + + W K G V D+ + +G + F + H S G Y C
Sbjct: 50 TLRCEADEN-TDRYSWLKDGEPFVIDSEDVLWEKESQSGSIVFTKP-HA---SHQGYYQC 104
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW--- 142
A+N +GTA S L + L + + + + +G+++ L C PPRG+P+P + W
Sbjct: 105 FASNIFGTALSNKMHLRLGSLEHFPKRDVKLLRVKEGESLTLNCTPPRGTPDPKIVWLYR 164
Query: 143 KKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR---YQCIARNAAGTRESAIAT-LK 197
+ +++ SR VD G+L +D Y+C A + E ++
Sbjct: 165 SLDDSSVIETIRSRHITVDNEGHLHFSSVELSDGKATLVYECAATSPVLRGEYRSGDRIQ 224
Query: 198 IHIKPY---------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ I+P + P +V + G + QC GG PLP + W S G +P R
Sbjct: 225 LDIEPSQDKSHPVKKMSVSPSEVTVRAGGQLKLQCIFGGRPLPTIFW--SKIDGELPKSR 282
Query: 249 VKVL-----DDG-SLRLDNVILADEGEYSCEAENSVGAVSA---SGYLTVYDPPSINLSP 299
+K L D G SL ++NV D G Y C + V V+ + +DP P
Sbjct: 283 IKDLTSHESDFGRSLIVENVHPDDAGAYECRGRHLVHTVNVRVMAAPFWEFDP------P 336
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+++ + C A G+P P + WS+ G ++ D + D +L +
Sbjct: 337 RDISLPEESTGELECLAGGQPTPIITWSMNGK---FLHELAEDS--RRVLLDHGRILRVR 391
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
+ + + C+A N G F + V + P + + + S V C
Sbjct: 392 NLNHDLDTGVYQCNASNPLGYVFANAFVHVRA---HAPFFRMPAARHWKVVLHSTVVLDC 448
Query: 420 TAICTPEPIIAWYFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
PE ++ W + +Q + + + T ++ D++ +D G Y C S+++G
Sbjct: 449 DVDAAPEAMVRWVDADDRPLQVVEGKNKLFPNHTFMVYDVNSADEGLYYCNVSNKYG 505
Score = 81.4 bits (192), Expect = 4e-15
Identities = 89/326 (27%), Positives = 128/326 (39%), Gaps = 22/326 (6%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV L C GG P P I W K + + + F VH
Sbjct: 244 PSEVTVRAGGQLKLQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVH 303
Query: 78 -SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
DAG Y C + T R +A EF P + T LECL G P
Sbjct: 304 PDDAGAYECRGRHLVHTVNVR----VMAAPFWEFD-PPRDISLPEESTGELECL-AGGQP 357
Query: 137 EPNVYWKKNGQTL-LFDGDSRMHLVDGGNLV-IQDA-RQTDAGRYQCIARNAAG-TRESA 192
P + W NG+ L DSR L+D G ++ +++ D G YQC A N G +A
Sbjct: 358 TPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLGYVFANA 417
Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----GR 248
++ H + + S+V C V P V W + PL G+
Sbjct: 418 FVHVRAHAPFFRMPAARHWKVVLHSTVVLDCDVDAAPEAMVRW---VDADDRPLQVVEGK 474
Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP-SINL-SPNSVNVES 306
K+ + + + +V ADEG Y C N G A+ L V+ P + + +P + +E+
Sbjct: 475 NKLFPNHTFMVYDVNSADEGLYYCNVSNKYGINRATNRLQVFKPTYFVRIPTPKRLILEA 534
Query: 307 GNVARFTCTATGRPE-PTMF-WSVEG 330
G A C A P P + W++ G
Sbjct: 535 GETAEVFCEAVADPRLPIRYQWTING 560
Score = 81.0 bits (191), Expect = 5e-15
Identities = 74/286 (25%), Positives = 113/286 (39%), Gaps = 13/286 (4%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL---VVSDTHRSILPAGGLFFLRAT 72
+ P D+++ L C AGG P+P I W G + D+ R +L G + LR
Sbjct: 334 DPPRDISLPEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRI--LRVR 391
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECL 130
+ D GVY C A+N G + NA +HV FR+ P ++ + TVVL+C
Sbjct: 392 NLNHDLDTGVYQCNASNPLGYVFA-NAFVHVRAHAPFFRM-PAARHWKVVLHSTVVLDC- 448
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
+PE V W L + + L ++ D D G Y C N G
Sbjct: 449 DVDAAPEAMVRWVDADDRPLQVVEGKNKLFPNHTFMVYDVNSADEGLYYCNVSNKYGINR 508
Query: 191 SAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
A L++ Y I P+ ++ + G + C DP + ++ + G + +
Sbjct: 509 -ATNRLQVFKPTYFVRIPTPKRLILEAGETAEVFCEAVADPRLPIRYQWTINGKVLTESQ 567
Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
+ LR +V G C A V AS L V D P+
Sbjct: 568 YYEILPDRLRFRSVRGRHSGIIDCAAITDVDVKLASMQLIVKDVPA 613
Score = 72.5 bits (170), Expect = 2e-12
Identities = 180/795 (22%), Positives = 294/795 (36%), Gaps = 121/795 (15%)
Query: 23 VARHQPATLNCRAG-GSPSPAIRW-YKG-----GVLVVSDTHRSILPAGGLFF--LRATH 73
V + TLNC G+P P I W Y+ + + H ++ G L F + +
Sbjct: 138 VKEGESLTLNCTPPRGTPDPKIVWLYRSLDDSSVIETIRSRHITVDNEGHLHFSSVELSD 197
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNAT-LHVAVLREEFRLEPESKQSAQ--------GDT 124
G+ VY C AT+ R+ + + + + + P K S G
Sbjct: 198 GKATL---VYECAATSPVLRGEYRSGDRIQLDIEPSQDKSHPVKKMSVSPSEVTVRAGGQ 254
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRMHLVD-GGNLVIQDARQTDAGRYQCI 181
+ L+C+ G P P ++W K L D H D G +L++++ DAG Y+C
Sbjct: 255 LKLQCIFG-GRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYECR 313
Query: 182 ARNAAGTRESAIATLKIHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
R+ T +++ P+ P D+ S+ +C GG P P + W +
Sbjct: 314 GRHLVHT-----VNVRVMAAPFWEFDPPRDISLPEESTGELECLAGGQPTPIITWSMNGK 368
Query: 241 GGNMPL--GRVKVLDDGS-LRLDNVIL-ADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ R +LD G LR+ N+ D G Y C A N +G V A+ ++ V
Sbjct: 369 FLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLGYVFANAFVHVRAHAPFF 428
Query: 297 LSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTI-IFPGMSR-DKYHATAVFDG 352
P + + V + C PE + W +R + + G ++ H V+D
Sbjct: 429 RMPAARHWKVVLHSTVVLDCDVDAAPEAMVRWVDADDRPLQVVEGKNKLFPNHTFMVYD- 487
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
+N D+ C+ N G + +L V P P+ + L ++
Sbjct: 488 -----VNSADEG----LYYCNVSNKYGINRATNRLQVFK-----PTYFVRIPTPKRLILE 533
Query: 413 S--MAVFPCTAICTPE-PI-IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
+ A C A+ P PI W G+ L ++ + D L + + SG C
Sbjct: 534 AGETAEVFCEAVADPRLPIRYQWTINGKVLTESQYYEILPD-RLRFRSVRGRHSGIIDCA 592
Query: 469 ASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
A + + S L+V D P +P + T + ++ T+ W
Sbjct: 593 AITDVDVKLASMQLIVKDVPAHPVVE------------------TAHCSERKATVKWVAA 634
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVH---QTHYVVKSLIPGITYM 584
+ G S I Y VE+F T W VI V+ +T V +L P + Y
Sbjct: 635 SDHGDS-IKKYIVEMF---------TDFKKNEWEVINEEVNVNKETFEVDITLTPWVNYT 684
Query: 585 FIVRTENSHGLSGPS----PVSDSVTVGDDSNSLWEG-TGVSNSTEYRNNILTDHIVELI 639
F V NSHG S P D +T + + TGV +N++ I
Sbjct: 685 FRVVAVNSHGRSDMKIDGQPKEDWLTCQTRPSFPYTNPTGVKGEGTEPDNLV-------I 737
Query: 640 EATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRK 699
P+D + W N YL + P+ T L + ++ F I +R
Sbjct: 738 SWKPLD----RYYWNAPNMQYLVR-YKLDEPIHGWT------EFLVEDSLANFTI--IRD 784
Query: 700 YTKYEFFLIPFYKKFEGKPS----NSRVAQTLDDVPDGPPINIEMFI-LNTTTVHLKWSP 754
+ +LI PS + +DVPD P + + +N TT++ W+P
Sbjct: 785 QPTFRKYLIQVQSVNSVGPSIVEPEIHHGWSGEDVPDEAPRDFHIDTQINFTTINFTWNP 844
Query: 755 PELQLQNGIITGYNV 769
+ NG GY +
Sbjct: 845 VDANTVNGHFVGYEI 859
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/183 (23%), Positives = 73/183 (39%), Gaps = 15/183 (8%)
Query: 642 TPIDSKTIKLMWEILNFYYLEGLFIYFR----PLDNITIEYEMKTILHSNDVSGFEITSL 697
T I+ TI W ++ + G F+ + +N +Y +K +S I S
Sbjct: 831 TQINFTTINFTWNPVDANTVNGHFVGYEIEYWKAENTIRKYSIKIPANSTYKV---INSF 887
Query: 698 RKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPEL 757
T Y + K+ PS+ V+ + + P G N+ ++ + +T + L+W P L
Sbjct: 888 HAVTNYSAHIRTRNKRLRSAPSDY-VSFAMPEGPPGKVHNLRVYSVGSTAILLQWDAP-L 945
Query: 758 QLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
Q NG I GY ++ K+ +H+ + Y V + AET G
Sbjct: 946 Q-PNGRIRGY-----FISFQNEKNETEETYVIHRQKHYLHEKSEPDTGYKVSVWAETRAG 999
Query: 818 LGP 820
GP
Sbjct: 1000 EGP 1002
>AC024817-49|AAF59572.3| 1187|Caenorhabditis elegans L1 cam adhesion
molecule homologprotein 2, isoform a protein.
Length = 1187
Score = 111 bits (266), Expect = 4e-24
Identities = 112/477 (23%), Positives = 194/477 (40%), Gaps = 53/477 (11%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP----AGGLFFLRATHGRVHSDAGVYWC 85
TL C A + + W K G V D+ + +G + F + H S G Y C
Sbjct: 50 TLRCEADEN-TDRYSWLKDGEPFVIDSEDVLWEKESQSGSIVFTKP-HA---SHQGYYQC 104
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW--- 142
A+N +GTA S L + L + + + + +G+++ L C PPRG+P+P + W
Sbjct: 105 FASNIFGTALSNKMHLRLGSLEHFPKRDVKLLRVKEGESLTLNCTPPRGTPDPKIVWLYR 164
Query: 143 KKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR---YQCIARNAAGTRESAIAT-LK 197
+ +++ SR VD G+L +D Y+C A + E ++
Sbjct: 165 SLDDSSVIETIRSRHITVDNEGHLHFSSVELSDGKATLVYECAATSPVLRGEYRSGDRIQ 224
Query: 198 IHIKPY---------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ I+P + P +V + G + QC GG PLP + W S G +P R
Sbjct: 225 LDIEPSQDKSHPVKKMSVSPSEVTVRAGGQLKLQCIFGGRPLPTIFW--SKIDGELPKSR 282
Query: 249 VKVL-----DDG-SLRLDNVILADEGEYSCEAENSVGAVSA---SGYLTVYDPPSINLSP 299
+K L D G SL ++NV D G Y C + V V+ + +DP P
Sbjct: 283 IKDLTSHESDFGRSLIVENVHPDDAGAYECRGRHLVHTVNVRVMAAPFWEFDP------P 336
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+++ + C A G+P P + WS+ G ++ D + D +L +
Sbjct: 337 RDISLPEESTGELECLAGGQPTPIITWSMNGK---FLHELAEDS--RRVLLDHGRILRVR 391
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
+ + + C+A N G F + V + P + + + S V C
Sbjct: 392 NLNHDLDTGVYQCNASNPLGYVFANAFVHVRA---HAPFFRMPAARHWKVVLHSTVVLDC 448
Query: 420 TAICTPEPIIAWYFEGEALIQ--NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
PE ++ W + +Q + + + T ++ D++ +D G Y C S+++G
Sbjct: 449 DVDAAPEAMVRWVDADDRPLQVVEGKNKLFPNHTFMVYDVNSADEGLYYCNVSNKYG 505
Score = 81.4 bits (192), Expect = 4e-15
Identities = 89/326 (27%), Positives = 128/326 (39%), Gaps = 22/326 (6%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV L C GG P P I W K + + + F VH
Sbjct: 244 PSEVTVRAGGQLKLQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVH 303
Query: 78 -SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
DAG Y C + T R +A EF P + T LECL G P
Sbjct: 304 PDDAGAYECRGRHLVHTVNVR----VMAAPFWEFD-PPRDISLPEESTGELECL-AGGQP 357
Query: 137 EPNVYWKKNGQTL-LFDGDSRMHLVDGGNLV-IQDA-RQTDAGRYQCIARNAAG-TRESA 192
P + W NG+ L DSR L+D G ++ +++ D G YQC A N G +A
Sbjct: 358 TPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLGYVFANA 417
Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL----GR 248
++ H + + S+V C V P V W + PL G+
Sbjct: 418 FVHVRAHAPFFRMPAARHWKVVLHSTVVLDCDVDAAPEAMVRW---VDADDRPLQVVEGK 474
Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP-SINL-SPNSVNVES 306
K+ + + + +V ADEG Y C N G A+ L V+ P + + +P + +E+
Sbjct: 475 NKLFPNHTFMVYDVNSADEGLYYCNVSNKYGINRATNRLQVFKPTYFVRIPTPKRLILEA 534
Query: 307 GNVARFTCTATGRPE-PTMF-WSVEG 330
G A C A P P + W++ G
Sbjct: 535 GETAEVFCEAVADPRLPIRYQWTING 560
Score = 81.0 bits (191), Expect = 5e-15
Identities = 74/286 (25%), Positives = 113/286 (39%), Gaps = 13/286 (4%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL---VVSDTHRSILPAGGLFFLRAT 72
+ P D+++ L C AGG P+P I W G + D+ R +L G + LR
Sbjct: 334 DPPRDISLPEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRI--LRVR 391
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECL 130
+ D GVY C A+N G + NA +HV FR+ P ++ + TVVL+C
Sbjct: 392 NLNHDLDTGVYQCNASNPLGYVFA-NAFVHVRAHAPFFRM-PAARHWKVVLHSTVVLDC- 448
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
+PE V W L + + L ++ D D G Y C N G
Sbjct: 449 DVDAAPEAMVRWVDADDRPLQVVEGKNKLFPNHTFMVYDVNSADEGLYYCNVSNKYGINR 508
Query: 191 SAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
A L++ Y I P+ ++ + G + C DP + ++ + G + +
Sbjct: 509 -ATNRLQVFKPTYFVRIPTPKRLILEAGETAEVFCEAVADPRLPIRYQWTINGKVLTESQ 567
Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
+ LR +V G C A V AS L V D P+
Sbjct: 568 YYEILPDRLRFRSVRGRHSGIIDCAAITDVDVKLASMQLIVKDVPA 613
Score = 72.5 bits (170), Expect = 2e-12
Identities = 180/795 (22%), Positives = 294/795 (36%), Gaps = 121/795 (15%)
Query: 23 VARHQPATLNCRAG-GSPSPAIRW-YKG-----GVLVVSDTHRSILPAGGLFF--LRATH 73
V + TLNC G+P P I W Y+ + + H ++ G L F + +
Sbjct: 138 VKEGESLTLNCTPPRGTPDPKIVWLYRSLDDSSVIETIRSRHITVDNEGHLHFSSVELSD 197
Query: 74 GRVHSDAGVYWCEATNSYGTARSRNAT-LHVAVLREEFRLEPESKQSAQ--------GDT 124
G+ VY C AT+ R+ + + + + + P K S G
Sbjct: 198 GKATL---VYECAATSPVLRGEYRSGDRIQLDIEPSQDKSHPVKKMSVSPSEVTVRAGGQ 254
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDG--DSRMHLVD-GGNLVIQDARQTDAGRYQCI 181
+ L+C+ G P P ++W K L D H D G +L++++ DAG Y+C
Sbjct: 255 LKLQCIFG-GRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVHPDDAGAYECR 313
Query: 182 ARNAAGTRESAIATLKIHIKPYL-ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
R+ T +++ P+ P D+ S+ +C GG P P + W +
Sbjct: 314 GRHLVHT-----VNVRVMAAPFWEFDPPRDISLPEESTGELECLAGGQPTPIITWSMNGK 368
Query: 241 GGNMPL--GRVKVLDDGS-LRLDNVIL-ADEGEYSCEAENSVGAVSASGYLTVYDPPSIN 296
+ R +LD G LR+ N+ D G Y C A N +G V A+ ++ V
Sbjct: 369 FLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLGYVFANAFVHVRAHAPFF 428
Query: 297 LSPNSVN--VESGNVARFTCTATGRPEPTMFWSVEGNRTI-IFPGMSR-DKYHATAVFDG 352
P + + V + C PE + W +R + + G ++ H V+D
Sbjct: 429 RMPAARHWKVVLHSTVVLDCDVDAAPEAMVRWVDADDRPLQVVEGKNKLFPNHTFMVYD- 487
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
+N D+ C+ N G + +L V P P+ + L ++
Sbjct: 488 -----VNSADEG----LYYCNVSNKYGINRATNRLQVFK-----PTYFVRIPTPKRLILE 533
Query: 413 S--MAVFPCTAICTPE-PI-IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
+ A C A+ P PI W G+ L ++ + D L + + SG C
Sbjct: 534 AGETAEVFCEAVADPRLPIRYQWTINGKVLTESQYYEILPD-RLRFRSVRGRHSGIIDCA 592
Query: 469 ASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
A + + S L+V D P +P + T + ++ T+ W
Sbjct: 593 AITDVDVKLASMQLIVKDVPAHPVVE------------------TAHCSERKATVKWVAA 634
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVH---QTHYVVKSLIPGITYM 584
+ G S I Y VE+F T W VI V+ +T V +L P + Y
Sbjct: 635 SDHGDS-IKKYIVEMF---------TDFKKNEWEVINEEVNVNKETFEVDITLTPWVNYT 684
Query: 585 FIVRTENSHGLSGPS----PVSDSVTVGDDSNSLWEG-TGVSNSTEYRNNILTDHIVELI 639
F V NSHG S P D +T + + TGV +N++ I
Sbjct: 685 FRVVAVNSHGRSDMKIDGQPKEDWLTCQTRPSFPYTNPTGVKGEGTEPDNLV-------I 737
Query: 640 EATPIDSKTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRK 699
P+D + W N YL + P+ T L + ++ F I +R
Sbjct: 738 SWKPLD----RYYWNAPNMQYLVR-YKLDEPIHGWT------EFLVEDSLANFTI--IRD 784
Query: 700 YTKYEFFLIPFYKKFEGKPS----NSRVAQTLDDVPDGPPINIEMFI-LNTTTVHLKWSP 754
+ +LI PS + +DVPD P + + +N TT++ W+P
Sbjct: 785 QPTFRKYLIQVQSVNSVGPSIVEPEIHHGWSGEDVPDEAPRDFHIDTQINFTTINFTWNP 844
Query: 755 PELQLQNGIITGYNV 769
+ NG GY +
Sbjct: 845 VDANTVNGHFVGYEI 859
Score = 42.3 bits (95), Expect = 0.002
Identities = 43/183 (23%), Positives = 73/183 (39%), Gaps = 15/183 (8%)
Query: 642 TPIDSKTIKLMWEILNFYYLEGLFIYFR----PLDNITIEYEMKTILHSNDVSGFEITSL 697
T I+ TI W ++ + G F+ + +N +Y +K +S I S
Sbjct: 831 TQINFTTINFTWNPVDANTVNGHFVGYEIEYWKAENTIRKYSIKIPANSTYKV---INSF 887
Query: 698 RKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPEL 757
T Y + K+ PS+ V+ + + P G N+ ++ + +T + L+W P L
Sbjct: 888 HAVTNYSAHIRTRNKRLRSAPSDY-VSFAMPEGPPGKVHNLRVYSVGSTAILLQWDAP-L 945
Query: 758 QLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
Q NG I GY ++ K+ +H+ + Y V + AET G
Sbjct: 946 Q-PNGRIRGY-----FISFQNEKNETEETYVIHRQKHYLHEKSEPDTGYKVSVWAETRAG 999
Query: 818 LGP 820
GP
Sbjct: 1000 EGP 1002
>AY130758-5|AAN61521.1| 2693|Caenorhabditis elegans 301KDa_2 protein
protein.
Length = 2693
Score = 106 bits (255), Expect = 8e-23
Identities = 134/531 (25%), Positives = 210/531 (39%), Gaps = 59/531 (11%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFL 69
AP +Q DV + L +P+P I W++ + S HR G +
Sbjct: 655 APSFGKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYS 714
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-----------FRLE-PESK 117
D+G Y C A N G A + +L + FR++ P +
Sbjct: 715 LTIIDAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPR 774
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177
+ QG + L C G+P PN+ W K+ + + H L I AR D GR
Sbjct: 775 EVPQGADLTLVC-SVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGARDDDQGR 833
Query: 178 YQCIARNAAGTRES------AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
Y C A N G +S A K H++P + + G+ + +C V G P+P
Sbjct: 834 YVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIP 893
Query: 232 DVLWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLT 288
+ W + + ++ D G RL+ NV++ D+GEY+CEA NS+G +
Sbjct: 894 TITWYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVK 953
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATG---RP----EPTMFWSV-EGNRTII----- 335
V D V S + +R G RP P +V EGNR ++
Sbjct: 954 VVDMGLSKTRLTPVRSRSRSRSRSPSVVGGEIQRPPVVTRPLADATVTEGNRELLEVEVD 1013
Query: 336 -FPGMSRDKYH----------ATAVFDG-VTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
FP + + YH FDG V L I + + + VC N G+
Sbjct: 1014 GFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKIYEAHE-EHNGQYVCKVSNKLGAVET 1072
Query: 384 RGKLTVTSDD--DRPPPIITNGPSNQTLPIKS---MAVFPCTAICTPEPIIAWYFEGEAL 438
R + V + D + + T Q + +K+ A F C + P + W G+AL
Sbjct: 1073 RAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKAL 1132
Query: 439 IQ---NHRRNVTND--GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
Q N++ + +D TLV++++ GTYT VA+++ G S L +
Sbjct: 1133 QQTKSNYKTRLFDDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTI 1183
Score = 103 bits (246), Expect = 1e-21
Identities = 124/505 (24%), Positives = 180/505 (35%), Gaps = 52/505 (10%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
Q L CR + W+K + S + H D G Y C
Sbjct: 1532 QQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQDTGKYRCV 1591
Query: 87 ATNSYGTARSR-NATLH--VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
TN YG A S N + + F + G + LEC GSP P V W
Sbjct: 1592 VTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLEC-KVEGSPAPEVSWT 1650
Query: 144 KNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKI- 198
K+G+ + R + GN L I A D G Y C A + AG + S + K
Sbjct: 1651 KDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSSMVMIAKTT 1710
Query: 199 ---------------HIKPYLITGPEDVVAQTGSS-VTFQCRVGGDPLPDVLWRRSAGGG 242
H KP P ++ S T + G+P P V W + G
Sbjct: 1711 GTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKD-GRE 1769
Query: 243 NMPLGRVK---VLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291
+ R+ V DG L + V+ G +SC+AEN G V A + V
Sbjct: 1770 ILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPANQ 1829
Query: 292 ----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV--EGNRTIIFPGMSRDKYH 345
P + + + +G+ +C TG PEPT+ W + I + D
Sbjct: 1830 LANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTD--W 1887
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--TSDDDRPPPIITNG 403
F V L ++ + R T C A N +G + + L V SD+ PP
Sbjct: 1888 TECRFGKVAELK-SERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPAGPPRFVKC 1946
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLVL--KDLDK 459
+ P+K F P P + WY + + + +T +D T VL K++
Sbjct: 1947 LQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIKNVSL 2006
Query: 460 SDSGTYTCVASSRHGKYVWSGALLV 484
+ G Y AS+ HG +G L V
Sbjct: 2007 ASLGMYFVEASNIHGVLRTAGRLNV 2031
Score = 89.4 bits (212), Expect = 1e-17
Identities = 130/511 (25%), Positives = 194/511 (37%), Gaps = 74/511 (14%)
Query: 29 ATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
ATL+C G PSP ++WYK L V GL L V SDAG Y C A
Sbjct: 445 ATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAEL-TVKNIVESDAGKYTCRA 503
Query: 88 TNSYGTARSRNATLHVAV---LREEFRLEP----ESKQSAQGDTVVLE---CLPPR---- 133
TN G+ + +A L V +++ + P + K VV+E +PP
Sbjct: 504 TNDLGSIMT-HAKLSVKADEKKKKKSKTSPAVIEKKKDRKTSKVVVIEEMIDMPPNFHHL 562
Query: 134 --------GSP-----------EPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQ 172
G P EP V W NG+ + + + + D G L I
Sbjct: 563 LQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYLRKHDKGRYELHILSVDS 622
Query: 173 TDAGRYQCIARNAAGTRES-AIATLKIHIKPYLIT-GPE--DVVAQTGSSVTFQCRVGGD 228
TD G+++ + +NA G ES A T+ I Y + G + DV + + + +
Sbjct: 623 TDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGKQLSDVKCSESDILKLEVNIQAN 682
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSAS 284
P P++ W R+ DDG SL + + D GEY C A+N +G
Sbjct: 683 PAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYAEDSGEYKCVAKNKIGKAHTV 742
Query: 285 GYLTVYD-------------PPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
+ + + P + P V G C+ +G P P + W+ +
Sbjct: 743 CCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWT-KD 801
Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG--SSFVRGKLT 388
++ I MS + +GV L I ++D + VC A N G SF ++
Sbjct: 802 DKPI---DMSNKQVRHE---NGVCTLHIIGA-RDDDQGRYVCEAENIHGVAQSFSVVEIK 854
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
D D P N + + V C P P I WY +G LI +R
Sbjct: 855 EAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQYT 914
Query: 449 D----GTLVLKDLDKSDSGTYTCVASSRHGK 475
D L + ++ +D G YTC A + GK
Sbjct: 915 DRKGVSRLNIMNVVMNDDGEYTCEAVNSLGK 945
Score = 88.2 bits (209), Expect = 3e-17
Identities = 127/555 (22%), Positives = 211/555 (38%), Gaps = 92/555 (16%)
Query: 9 GEAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G+AP P +A R + G+P+P+++WYK + +V D +
Sbjct: 1405 GQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVATTSTSS 1464
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PE---------- 115
L + + G + C N G A +A+ V + + L+ P+
Sbjct: 1465 ILNL---KSQEENGTFNCLIENELGQA---SASCQVTIFNKPASLQSTPDHSLERNLVPT 1518
Query: 116 -----SKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVI 167
+ +SAQ G ++L C S E V W K+ + + G + N LV
Sbjct: 1519 LQKALNNESAQAGQQIMLTCRISSRS-ESTVAWFKDDERIESAGRYELSSDKKSNHKLVC 1577
Query: 168 QDARQTDAGRYQCIARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
+ D G+Y+C+ N G ES A+ + I P D A G ++T +C
Sbjct: 1578 HAVQSQDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLEC 1637
Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVG 279
+V G P P+V W + G R++ D + L + D G Y C A + G
Sbjct: 1638 KVEGSPAPEVSWTKD-GERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAG 1696
Query: 280 AVSASGYLTV-------------------YDPPSINLSPNSVNVESGNVARFT--CTATG 318
S S + + ++ P +P S+ +E +FT A G
Sbjct: 1697 VDSTSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSL-IEVNESGQFTLIAKAVG 1755
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
P+PT+ W +G + + YH DG + L I + + + C A N
Sbjct: 1756 EPKPTVTWLKDGREIL----RTNRIYHHFVTGDGESHL-IAECVVSKTSGIFSCKAENPN 1810
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV---FPCTAIC----TPEPIIAW 431
G+ V + V +P + N T+P+ M + P T C +PEP + W
Sbjct: 1811 GT--VIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEW 1868
Query: 432 YFEGEALIQNHRRNVTNDGT------------LVLKDLDKSDSGTYTCVASSRHGKYVWS 479
+ ++ H+ N+T+ T L + + + GTY C+A++ G+
Sbjct: 1869 IYIDDS---GHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQ 1925
Query: 480 GALLV----DSPINP 490
LLV D P P
Sbjct: 1926 CYLLVGELSDEPAGP 1940
Score = 84.6 bits (200), Expect = 4e-16
Identities = 115/510 (22%), Positives = 200/510 (39%), Gaps = 73/510 (14%)
Query: 39 PSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
P P + WY G + ++D++ G + L +D G + N++G S
Sbjct: 584 PEPTVDWYHNGEHISINDSNYLRKHDKGRYELHILSVD-STDEGKWKAVGKNAFGECESE 642
Query: 98 NATLHVAV----LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG 153
A L V + F + + ++ D + LE + + +P P + W +N +
Sbjct: 643 -AKLTVVIPDGQYAPSFGKQLSDVKCSESDILKLE-VNIQANPAPEINWFRNESEIEHSQ 700
Query: 154 DSRMHLVDG-GN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH----IKPYLIT 206
R+ DG GN L I DA D+G Y+C+A+N G + + ++I + I
Sbjct: 701 HHRLQFDDGSGNYSLTIIDAYAEDSGEYKCVAKNKIG-KAHTVCCVRIEELLSKRSKKID 759
Query: 207 G----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG- 255
G P G+ +T C V G P P++ W + +M +V+ ++G
Sbjct: 760 GSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVR-HENGV 818
Query: 256 -SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--------PPSINLSPNSVNVES 306
+L + D+G Y CEAEN G + + + + P + N E
Sbjct: 819 CTLHIIGARDDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCE- 877
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
GN C TG+P PT+ W +G + II ++ GV+ L I + ND
Sbjct: 878 GNEMVLECCVTGKPIPTITWYKDGLKLII-----ENRMLQYTDRKGVSRLNIMNVVMNDD 932
Query: 367 RNTIVCSAVNYAGSSFV------------RGKLT--------------VTSDDDRPPPII 400
C AVN G F + +LT V + + PP++
Sbjct: 933 -GEYTCEAVNSLGKDFTHCTVKVVDMGLSKTRLTPVRSRSRSRSRSPSVVGGEIQRPPVV 991
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDL 457
T ++ T+ + + P P I WY +G+ + ++ DG L + +
Sbjct: 992 TRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKIYEA 1051
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ +G Y C S++ G ++V++P
Sbjct: 1052 HEEHNGQYVCKVSNKLGAVETRAIVVVEAP 1081
Score = 79.8 bits (188), Expect = 1e-14
Identities = 82/338 (24%), Positives = 132/338 (39%), Gaps = 27/338 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P ++ +PL D TV L G P+P I WY G LV G + F
Sbjct: 986 QRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAF 1045
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSR--------NATLHVAVLREEFRLEPESKQSA 120
L+ + G Y C+ +N G +R +A HV + + +
Sbjct: 1046 LKIYEAHEEHN-GQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 1104
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDG--GNLVIQDARQTDAGR 177
G+T C +P V W NG+ L + + L D LVI++ G
Sbjct: 1105 AGETATFTC-QSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGT 1163
Query: 178 YQCIARNAAG-TRESAIATL------KIHIK-PYLITGPEDVV-AQTGSSVTFQCRVGGD 228
Y +A N G SA T+ KI PY I + + G++++ Q + G
Sbjct: 1164 YTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGS 1223
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P+P+V+W + + R+++ DG L + +V L DEG Y+ AEN G + +
Sbjct: 1224 PIPEVVWLKD-NSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNT 1282
Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
++V + VE + + G P P+
Sbjct: 1283 EVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPS 1320
Score = 68.1 bits (159), Expect = 4e-11
Identities = 106/471 (22%), Positives = 178/471 (37%), Gaps = 66/471 (14%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F + P+SK A D + G+P P+V W K + L D ++ + I
Sbjct: 1409 QFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYK--ENLQIVPDEKIDVATTSTSSIL 1466
Query: 169 DAR-QTDAGRYQCIARNAAGTRESAIA----------------TLKIHIKPYLITGPEDV 211
+ + Q + G + C+ N G ++ +L+ ++ P L +
Sbjct: 1467 NLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKALNNE 1526
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
AQ G + CR+ V W R G L K + L V D
Sbjct: 1527 SAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDK-KSNHKLVCHAVQSQDT 1585
Query: 268 GEYSCEAENSVGAVSASGYLTVYD-----PPSINLSPNSVNVESGNVARFTCTATGRPEP 322
G+Y C N G + + V D PS + + + G+ C G P P
Sbjct: 1586 GKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAP 1645
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG--- 379
+ W+ +G R + + T +G L+I+ + +D VCSA + AG
Sbjct: 1646 EVSWTKDGERI-----STTRRIRQTQDENGNCKLSISKAE-SDDMGVYVCSATSVAGVDS 1699
Query: 380 -SSFVR-GKLT---------VTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTAICTPE 426
SS V K T T+D+ P T P + + + F A+ P+
Sbjct: 1700 TSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPS-LIEVNESGQFTLIAKAVGEPK 1758
Query: 427 PIIAWYFEGEALIQNHR---RNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P + W +G +++ +R VT DG L+ + + SG ++C A + +G +
Sbjct: 1759 PTVTWLKDGREILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQ 1818
Query: 482 LLVD--SPIN--PNI---HFFRAADVSSLPGPPTKPITHNVTDT-SVTLSW 524
++V P N N+ D+ + G PT ++ NVT + TL W
Sbjct: 1819 VIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPT-TLSCNVTGSPEPTLEW 1868
Score = 68.1 bits (159), Expect = 4e-11
Identities = 100/393 (25%), Positives = 148/393 (37%), Gaps = 52/393 (13%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG----LFFLRATHGRVHSDAGVYWCE 86
+ C P +I W + V ++ R + G L F+ T G D G Y CE
Sbjct: 2300 VECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPG----DEGTYACE 2355
Query: 87 ATNSYGTARSRNATLHVAVLREE--------FRLEP--ESKQSAQGDTVVLECLPPRGSP 136
A N G+A + N L V+ + FR E ++ G V L + S
Sbjct: 2356 AVNELGSAVT-NMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASE 2414
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
+ W +N T++ D S + L I D D G Y A+N +G A
Sbjct: 2415 PLQIRWLRNKVTIV-DSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGI---ARC 2470
Query: 195 TLKIHIK----------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
T+++ ++ P + + G SV + +V G P P + W ++ N
Sbjct: 2471 TMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNN 2530
Query: 245 PLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP-------PS 294
+ + ++G LR+ NV AD G+Y A N G +A LTV P
Sbjct: 2531 E-EKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPK 2589
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
N SP SV N A + +G P P W GN I G+ D Y T+ D +
Sbjct: 2590 FNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELI--DGL--DGYTITS-SDTNS 2644
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
L IN DK +C+ N G +
Sbjct: 2645 SLLINSVDKKHF-GEYLCTIRNQNGEELANAMI 2676
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/201 (27%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Query: 6 VTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
+ +AP + ++ P V + TL C G+P P I+W K + +++ +
Sbjct: 758 IDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDD-KPIDMSNKQVRHEN 816
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-LHVAVLREEFR---LEP-ESKQS 119
G+ L R D G Y CEA N +G A+S + + AV ++ R LEP + +
Sbjct: 817 GVCTLHIIGAR-DDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCST 875
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177
+G+ +VLEC G P P + W K+G L+ + + G L I + D G
Sbjct: 876 CEGNEMVLECC-VTGKPIPTITWYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGE 934
Query: 178 YQCIARNAAGTRESAIATLKI 198
Y C A N+ G ++ T+K+
Sbjct: 935 YTCEAVNSLG-KDFTHCTVKV 954
Score = 62.1 bits (144), Expect = 2e-09
Identities = 70/318 (22%), Positives = 126/318 (39%), Gaps = 33/318 (10%)
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
+R+ + +R ++ +I +P ++T P D G+ + V G P P + W
Sbjct: 969 SRSRSRSRSPSVVGGEIQ-RPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHD-- 1025
Query: 241 GGNMPLGR-VKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPS-- 294
G + R ++ DG + + A E G+Y C+ N +GAV + V P +
Sbjct: 1026 GKLVAESRTLRTYFDGRVAFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAE 1085
Query: 295 -INLSPNSVNV-------ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
+ P V +G A FTC + P + W G ++ Y
Sbjct: 1086 HVTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKAL----QQTKSNYK- 1140
Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR------PPPII 400
T +FD T + + ++ T A N G +LT++ + + P II
Sbjct: 1141 TRLFDDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFII 1200
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDL 457
P + ++++ +P P + W + L+++ R + DG L+++D+
Sbjct: 1201 ELKPKINVVEGATLSI-QADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDV 1259
Query: 458 DKSDSGTYTCVASSRHGK 475
D GTYT A + GK
Sbjct: 1260 GLEDEGTYTITAENEKGK 1277
Score = 62.1 bits (144), Expect = 2e-09
Identities = 106/502 (21%), Positives = 180/502 (35%), Gaps = 60/502 (11%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L G+P P + W K G+++ + SI G ++L H D G Y C A N+
Sbjct: 2187 LKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVHHVSTF-DKGFYNCTAANN 2245
Query: 91 YG--TARSRNATLH------VAVLREEFRLE----------PESKQSAQGDTVVLECLPP 132
G T S L V + + R E P Q+ +++ +EC
Sbjct: 2246 EGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEVLPGRSQANLNESLCVEC-SV 2304
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRE 190
P ++ W +N LL D DG +L D G Y C A N G+
Sbjct: 2305 SAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAV 2364
Query: 191 SAIATLKIHIKPYLITGPEDVV----------AQTGSSVTFQCRV--GGDPLPDVLWRRS 238
+ + + P G + GS V + +PL + W R+
Sbjct: 2365 TNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPL-QIRWLRN 2423
Query: 239 AGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----- 291
+ + + L + +V D GEY+ EA+N G + L V +
Sbjct: 2424 KVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSV 2483
Query: 292 ----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P + P + + + G G P+P + W+ G + + +KY
Sbjct: 2484 ADEAPRVFDFEPTTRS-DPGVSVELRAKVIGHPDPVISWTKAGQKL-----NNEEKYMMR 2537
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR--PPPIITNGPS 405
D + N T + + + +A+N +G + +LTV P P
Sbjct: 2538 NEGDKFILRIANVTRADAGKYEL--TAINPSGQANAELELTVVQSTKTVGAKPKFNESPI 2595
Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-HRRNVTNDGT---LVLKDLDKSD 461
+ K+ A + TP P W++ G LI +T+ T L++ +DK
Sbjct: 2596 SVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKKH 2655
Query: 462 SGTYTCVASSRHGKYVWSGALL 483
G Y C +++G+ + + +L
Sbjct: 2656 FGEYLCTIRNQNGEELANAMIL 2677
Score = 59.7 bits (138), Expect = 1e-08
Identities = 108/529 (20%), Positives = 185/529 (34%), Gaps = 59/529 (11%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
+IIE + V ++ GSP P + W K +V ++ R + G+ +
Sbjct: 1198 FIIELKPKINVVEGATLSIQADLNGSPIPEVVWLKDNSELV-ESDRIQMKCDGVNYQLLV 1256
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
D G Y A N G R +N + V +E + + E K+ + D + P
Sbjct: 1257 RDVGLEDEGTYTITAENEKGKIR-QNTEVSVTKSKE-VKEKKEKKKVEKKDEGKKKPGRP 1314
Query: 133 RGSPEPNVYWKKNGQTLLFDGDS---------------RMHLVDGGN-----LVIQDARQ 172
G P P+ K T+ FD S + V G+ L I+
Sbjct: 1315 -GLPRPSGASKTEQVTMAFDAPSEGPADSYEVERRCPDQREWVSCGSTKSLELEIKGLTP 1373
Query: 173 TDAGRYQCIARNAAGTRE-----SAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVG 226
++ +N G E S + T + P P+ ++A
Sbjct: 1374 NTEYIFRVAGKNKQGLGEWSEMTSTLKTASVGQAPQFTISPQSKIIANRDDEFEIAVEFS 1433
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE-GEYSCEAENSVGAVSASG 285
G P P V W + +P ++ V + + N+ +E G ++C EN +G SAS
Sbjct: 1434 GTPTPSVKWYKE-NLQIVPDEKIDVATTSTSSILNLKSQEENGTFNCLIENELGQASASC 1492
Query: 286 YLTVYDPPSI-----------NLSP------NSVNVESGNVARFTCTATGRPEPTMFWSV 328
+T+++ P+ NL P N+ + ++G TC + R E T+ W
Sbjct: 1493 QVTIFNKPASLQSTPDHSLERNLVPTLQKALNNESAQAGQQIMLTCRISSRSESTVAWFK 1552
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
+ R S +Y ++ L + D+ C N G + +
Sbjct: 1553 DDERI-----ESAGRYELSSDKKSNHKLVCHAVQSQDT-GKYRCVVTNKYGYAESECNVA 1606
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
V P + S+ T + C +P P ++W +GE + R T
Sbjct: 1607 VEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQ 1666
Query: 449 DGT----LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
D L + + D G Y C A+S G S +++ + H
Sbjct: 1667 DENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSH 1715
Score = 58.8 bits (136), Expect = 2e-08
Identities = 75/322 (23%), Positives = 109/322 (33%), Gaps = 39/322 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAG 64
VT AP D T TL C+ GSP+P + W K G + + R
Sbjct: 1610 VTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQDEN 1669
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGT---------ARSRNATLHVAVL--------R 107
G L + D GVY C AT+ G A++ H+ + +
Sbjct: 1670 GNCKLSISKAE-SDDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSHLVIAQTADEKHEK 1728
Query: 108 EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GN 164
F P S G P+P V W K+G+ +L H V G +
Sbjct: 1729 PRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKDGREILRTNRIYHHFVTGDGESH 1788
Query: 165 LVIQDARQTDAGRYQCIARNAAGT--RESAIATLKI-------HIKPYLITGPEDVVAQT 215
L+ + +G + C A N GT E+ + ++ ++ P D+
Sbjct: 1789 LIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVN 1848
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--------DGSLRLDNVILADE 267
G T C V G P P + W G+ D L+ + V+
Sbjct: 1849 GHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQR 1908
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A NS G + YL V
Sbjct: 1909 GTYQCIATNSSGQATTQCYLLV 1930
Score = 58.8 bits (136), Expect = 2e-08
Identities = 91/415 (21%), Positives = 163/415 (39%), Gaps = 54/415 (13%)
Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
V R +F ++P+ ++ + + G+P P V+W K G ++ + ++ + + G+
Sbjct: 2164 VCRPKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEG--IILETGNKYSIYNDGD 2221
Query: 165 ---LVIQDARQTDAGRYQCIARNAAG------------TRESAIATL-------KIHIKP 202
L + D G Y C A N G +E + A + +
Sbjct: 2222 FYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPN 2281
Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRL 259
++ P A S+ +C V P ++W R++ R + DG SL+
Sbjct: 2282 FIEVLPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKF 2341
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSP--------NSV-NVESGN 308
+V DEG Y+CEA N +G+ + L V DP + P SV V G+
Sbjct: 2342 ISVTPGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGS 2401
Query: 309 VARFTCTATGRPEPTMFWSVEGNRTII-FPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
EP + TI+ P S + + + LTI D D
Sbjct: 2402 RVELAAELVQASEPLQIRWLRNKVTIVDSPSFSYSR------SENMVFLTIADVFPEDGG 2455
Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDD----DRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
V A N +G + +L V +++ D P + P+ ++ P S+ + I
Sbjct: 2456 EYTV-EAKNQSGIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVEL-RAKVIG 2513
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGK 475
P+P+I+W G+ L + + N+G L + ++ ++D+G Y A + G+
Sbjct: 2514 HPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQ 2568
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
Query: 209 EDVVAQTGSSV-TFQCRVGGDPLPDVLWRRSAGGGNMPLGRV-KVLDDG--SLRLDNVIL 264
ED+VA G + T C V G P P V W + +P + ++G L + N++
Sbjct: 434 EDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVE 493
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV 289
+D G+Y+C A N +G++ L+V
Sbjct: 494 SDAGKYTCRATNDLGSIMTHAKLSV 518
Score = 37.9 bits (84), Expect = 0.043
Identities = 44/189 (23%), Positives = 69/189 (36%), Gaps = 21/189 (11%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV--- 76
D+ + P TL+C GSP P + W + + H+ L + + G+V
Sbjct: 1843 DMGIVNGHPTTLSCNVTGSPEPTLEW----IYIDDSGHKINLTSSTTDWTECRFGKVAEL 1898
Query: 77 ------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE-- 128
G Y C ATNS G A ++ L V L +E P + Q L+
Sbjct: 1899 KSERVLREQRGTYQCIATNSSGQATTQ-CYLLVGELSDEPAGPPRFVKCLQDTWTPLKES 1957
Query: 129 ---CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIAR 183
+ G P P++ W N + + D ++ L I++ G Y A
Sbjct: 1958 IEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEAS 2017
Query: 184 NAAGTRESA 192
N G +A
Sbjct: 2018 NIHGVLRTA 2026
Score = 37.1 bits (82), Expect = 0.076
Identities = 28/111 (25%), Positives = 52/111 (46%), Gaps = 11/111 (9%)
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
R A +R + K +KP P V+ + S+ + + G+P+P V W + G
Sbjct: 2154 RAAINSRNKRVCRPKFMVKPK----PRKVLEEY-KSLRLKTAISGNPMPQVHWDKE--GI 2206
Query: 243 NMPLG-RVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+ G + + +DG L + +V D+G Y+C A N+ G ++ + + V
Sbjct: 2207 ILETGNKYSIYNDGDFYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDV 2257
Score = 34.7 bits (76), Expect = 0.40
Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Query: 569 QTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRN 628
Q + +L+PG +Y F VR +N+ G S PS S+ V V + S + E + +
Sbjct: 17 QAFITLFNLVPGESYRFRVRADNTFGQSEPSDESELVVVKNVSRVVEEPKKKEVKVKEQE 76
Query: 629 NILTDHIVELIEATPIDSKTIKL 651
++ + + + ++ P + KTI +
Sbjct: 77 SVDYERVAK--DSEPSEYKTIDI 97
Score = 34.3 bits (75), Expect = 0.53
Identities = 15/43 (34%), Positives = 19/43 (44%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG 49
T G P E P+ V A L G+P+PA RW+ G
Sbjct: 2583 TVGAKPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNG 2625
Score = 33.5 bits (73), Expect = 0.93
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRR--NVTNDGT--LVLKDLDKSDSGTYTCVA 469
+A C P P + WY + + L + + N+G L +K++ +SD+G YTC A
Sbjct: 444 IATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRA 503
Query: 470 SSRHGKYVWSGALLV 484
++ G + L V
Sbjct: 504 TNDLGSIMTHAKLSV 518
Score = 33.1 bits (72), Expect = 1.2
Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 2/69 (2%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQ 179
GD + G P P V W K+ + L + G L +++ ++DAG+Y
Sbjct: 441 GDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYT 500
Query: 180 CIARNAAGT 188
C A N G+
Sbjct: 501 CRATNDLGS 509
>AY130758-4|AAN61520.1| 2708|Caenorhabditis elegans 301KDa_1 protein
protein.
Length = 2708
Score = 106 bits (255), Expect = 8e-23
Identities = 134/531 (25%), Positives = 210/531 (39%), Gaps = 59/531 (11%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFL 69
AP +Q DV + L +P+P I W++ + S HR G +
Sbjct: 670 APSFGKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYS 729
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-----------FRLE-PESK 117
D+G Y C A N G A + +L + FR++ P +
Sbjct: 730 LTIIDAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPR 789
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177
+ QG + L C G+P PN+ W K+ + + H L I AR D GR
Sbjct: 790 EVPQGADLTLVC-SVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGARDDDQGR 848
Query: 178 YQCIARNAAGTRES------AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
Y C A N G +S A K H++P + + G+ + +C V G P+P
Sbjct: 849 YVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIP 908
Query: 232 DVLWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLT 288
+ W + + ++ D G RL+ NV++ D+GEY+CEA NS+G +
Sbjct: 909 TITWYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVK 968
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATG---RP----EPTMFWSV-EGNRTII----- 335
V D V S + +R G RP P +V EGNR ++
Sbjct: 969 VVDMGLSKTRLTPVRSRSRSRSRSPSVVGGEIQRPPVVTRPLADATVTEGNRELLEVEVD 1028
Query: 336 -FPGMSRDKYH----------ATAVFDG-VTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
FP + + YH FDG V L I + + + VC N G+
Sbjct: 1029 GFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKIYEAHE-EHNGQYVCKVSNKLGAVET 1087
Query: 384 RGKLTVTSDD--DRPPPIITNGPSNQTLPIKS---MAVFPCTAICTPEPIIAWYFEGEAL 438
R + V + D + + T Q + +K+ A F C + P + W G+AL
Sbjct: 1088 RAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKAL 1147
Query: 439 IQ---NHRRNVTND--GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
Q N++ + +D TLV++++ GTYT VA+++ G S L +
Sbjct: 1148 QQTKSNYKTRLFDDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTI 1198
Score = 103 bits (246), Expect = 1e-21
Identities = 124/505 (24%), Positives = 180/505 (35%), Gaps = 52/505 (10%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
Q L CR + W+K + S + H D G Y C
Sbjct: 1547 QQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQDTGKYRCV 1606
Query: 87 ATNSYGTARSR-NATLH--VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
TN YG A S N + + F + G + LEC GSP P V W
Sbjct: 1607 VTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLEC-KVEGSPAPEVSWT 1665
Query: 144 KNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKI- 198
K+G+ + R + GN L I A D G Y C A + AG + S + K
Sbjct: 1666 KDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSSMVMIAKTT 1725
Query: 199 ---------------HIKPYLITGPEDVVAQTGSS-VTFQCRVGGDPLPDVLWRRSAGGG 242
H KP P ++ S T + G+P P V W + G
Sbjct: 1726 GTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKD-GRE 1784
Query: 243 NMPLGRVK---VLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291
+ R+ V DG L + V+ G +SC+AEN G V A + V
Sbjct: 1785 ILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPANQ 1844
Query: 292 ----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV--EGNRTIIFPGMSRDKYH 345
P + + + +G+ +C TG PEPT+ W + I + D
Sbjct: 1845 LANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTD--W 1902
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--TSDDDRPPPIITNG 403
F V L ++ + R T C A N +G + + L V SD+ PP
Sbjct: 1903 TECRFGKVAELK-SERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPAGPPRFVKC 1961
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLVL--KDLDK 459
+ P+K F P P + WY + + + +T +D T VL K++
Sbjct: 1962 LQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIKNVSL 2021
Query: 460 SDSGTYTCVASSRHGKYVWSGALLV 484
+ G Y AS+ HG +G L V
Sbjct: 2022 ASLGMYFVEASNIHGVLRTAGRLNV 2046
Score = 89.4 bits (212), Expect = 1e-17
Identities = 130/511 (25%), Positives = 194/511 (37%), Gaps = 74/511 (14%)
Query: 29 ATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
ATL+C G PSP ++WYK L V GL L V SDAG Y C A
Sbjct: 460 ATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAEL-TVKNIVESDAGKYTCRA 518
Query: 88 TNSYGTARSRNATLHVAV---LREEFRLEP----ESKQSAQGDTVVLE---CLPPR---- 133
TN G+ + +A L V +++ + P + K VV+E +PP
Sbjct: 519 TNDLGSIMT-HAKLSVKADEKKKKKSKTSPAVIEKKKDRKTSKVVVIEEMIDMPPNFHHL 577
Query: 134 --------GSP-----------EPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQ 172
G P EP V W NG+ + + + + D G L I
Sbjct: 578 LQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYLRKHDKGRYELHILSVDS 637
Query: 173 TDAGRYQCIARNAAGTRES-AIATLKIHIKPYLIT-GPE--DVVAQTGSSVTFQCRVGGD 228
TD G+++ + +NA G ES A T+ I Y + G + DV + + + +
Sbjct: 638 TDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGKQLSDVKCSESDILKLEVNIQAN 697
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSAS 284
P P++ W R+ DDG SL + + D GEY C A+N +G
Sbjct: 698 PAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYAEDSGEYKCVAKNKIGKAHTV 757
Query: 285 GYLTVYD-------------PPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
+ + + P + P V G C+ +G P P + W+ +
Sbjct: 758 CCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWT-KD 816
Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG--SSFVRGKLT 388
++ I MS + +GV L I ++D + VC A N G SF ++
Sbjct: 817 DKPI---DMSNKQVRHE---NGVCTLHIIGA-RDDDQGRYVCEAENIHGVAQSFSVVEIK 869
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
D D P N + + V C P P I WY +G LI +R
Sbjct: 870 EAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQYT 929
Query: 449 D----GTLVLKDLDKSDSGTYTCVASSRHGK 475
D L + ++ +D G YTC A + GK
Sbjct: 930 DRKGVSRLNIMNVVMNDDGEYTCEAVNSLGK 960
Score = 88.2 bits (209), Expect = 3e-17
Identities = 127/555 (22%), Positives = 211/555 (38%), Gaps = 92/555 (16%)
Query: 9 GEAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G+AP P +A R + G+P+P+++WYK + +V D +
Sbjct: 1420 GQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVATTSTSS 1479
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PE---------- 115
L + + G + C N G A +A+ V + + L+ P+
Sbjct: 1480 ILNL---KSQEENGTFNCLIENELGQA---SASCQVTIFNKPASLQSTPDHSLERNLVPT 1533
Query: 116 -----SKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVI 167
+ +SAQ G ++L C S E V W K+ + + G + N LV
Sbjct: 1534 LQKALNNESAQAGQQIMLTCRISSRS-ESTVAWFKDDERIESAGRYELSSDKKSNHKLVC 1592
Query: 168 QDARQTDAGRYQCIARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
+ D G+Y+C+ N G ES A+ + I P D A G ++T +C
Sbjct: 1593 HAVQSQDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLEC 1652
Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVG 279
+V G P P+V W + G R++ D + L + D G Y C A + G
Sbjct: 1653 KVEGSPAPEVSWTKD-GERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAG 1711
Query: 280 AVSASGYLTV-------------------YDPPSINLSPNSVNVESGNVARFT--CTATG 318
S S + + ++ P +P S+ +E +FT A G
Sbjct: 1712 VDSTSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSL-IEVNESGQFTLIAKAVG 1770
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
P+PT+ W +G + + YH DG + L I + + + C A N
Sbjct: 1771 EPKPTVTWLKDGREIL----RTNRIYHHFVTGDGESHL-IAECVVSKTSGIFSCKAENPN 1825
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV---FPCTAIC----TPEPIIAW 431
G+ V + V +P + N T+P+ M + P T C +PEP + W
Sbjct: 1826 GT--VIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEW 1883
Query: 432 YFEGEALIQNHRRNVTNDGT------------LVLKDLDKSDSGTYTCVASSRHGKYVWS 479
+ ++ H+ N+T+ T L + + + GTY C+A++ G+
Sbjct: 1884 IYIDDS---GHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQ 1940
Query: 480 GALLV----DSPINP 490
LLV D P P
Sbjct: 1941 CYLLVGELSDEPAGP 1955
Score = 84.6 bits (200), Expect = 4e-16
Identities = 115/510 (22%), Positives = 200/510 (39%), Gaps = 73/510 (14%)
Query: 39 PSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
P P + WY G + ++D++ G + L +D G + N++G S
Sbjct: 599 PEPTVDWYHNGEHISINDSNYLRKHDKGRYELHILSVD-STDEGKWKAVGKNAFGECESE 657
Query: 98 NATLHVAV----LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG 153
A L V + F + + ++ D + LE + + +P P + W +N +
Sbjct: 658 -AKLTVVIPDGQYAPSFGKQLSDVKCSESDILKLE-VNIQANPAPEINWFRNESEIEHSQ 715
Query: 154 DSRMHLVDG-GN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH----IKPYLIT 206
R+ DG GN L I DA D+G Y+C+A+N G + + ++I + I
Sbjct: 716 HHRLQFDDGSGNYSLTIIDAYAEDSGEYKCVAKNKIG-KAHTVCCVRIEELLSKRSKKID 774
Query: 207 G----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG- 255
G P G+ +T C V G P P++ W + +M +V+ ++G
Sbjct: 775 GSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVR-HENGV 833
Query: 256 -SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--------PPSINLSPNSVNVES 306
+L + D+G Y CEAEN G + + + + P + N E
Sbjct: 834 CTLHIIGARDDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCE- 892
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
GN C TG+P PT+ W +G + II ++ GV+ L I + ND
Sbjct: 893 GNEMVLECCVTGKPIPTITWYKDGLKLII-----ENRMLQYTDRKGVSRLNIMNVVMNDD 947
Query: 367 RNTIVCSAVNYAGSSFV------------RGKLT--------------VTSDDDRPPPII 400
C AVN G F + +LT V + + PP++
Sbjct: 948 -GEYTCEAVNSLGKDFTHCTVKVVDMGLSKTRLTPVRSRSRSRSRSPSVVGGEIQRPPVV 1006
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDL 457
T ++ T+ + + P P I WY +G+ + ++ DG L + +
Sbjct: 1007 TRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKIYEA 1066
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ +G Y C S++ G ++V++P
Sbjct: 1067 HEEHNGQYVCKVSNKLGAVETRAIVVVEAP 1096
Score = 79.8 bits (188), Expect = 1e-14
Identities = 82/338 (24%), Positives = 132/338 (39%), Gaps = 27/338 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P ++ +PL D TV L G P+P I WY G LV G + F
Sbjct: 1001 QRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAF 1060
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSR--------NATLHVAVLREEFRLEPESKQSA 120
L+ + G Y C+ +N G +R +A HV + + +
Sbjct: 1061 LKIYEAHEEHN-GQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 1119
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDG--GNLVIQDARQTDAGR 177
G+T C +P V W NG+ L + + L D LVI++ G
Sbjct: 1120 AGETATFTC-QSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGT 1178
Query: 178 YQCIARNAAG-TRESAIATL------KIHIK-PYLITGPEDVV-AQTGSSVTFQCRVGGD 228
Y +A N G SA T+ KI PY I + + G++++ Q + G
Sbjct: 1179 YTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGS 1238
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P+P+V+W + + R+++ DG L + +V L DEG Y+ AEN G + +
Sbjct: 1239 PIPEVVWLKD-NSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNT 1297
Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
++V + VE + + G P P+
Sbjct: 1298 EVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPS 1335
Score = 68.1 bits (159), Expect = 4e-11
Identities = 106/471 (22%), Positives = 178/471 (37%), Gaps = 66/471 (14%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F + P+SK A D + G+P P+V W K + L D ++ + I
Sbjct: 1424 QFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYK--ENLQIVPDEKIDVATTSTSSIL 1481
Query: 169 DAR-QTDAGRYQCIARNAAGTRESAIA----------------TLKIHIKPYLITGPEDV 211
+ + Q + G + C+ N G ++ +L+ ++ P L +
Sbjct: 1482 NLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKALNNE 1541
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
AQ G + CR+ V W R G L K + L V D
Sbjct: 1542 SAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDK-KSNHKLVCHAVQSQDT 1600
Query: 268 GEYSCEAENSVGAVSASGYLTVYD-----PPSINLSPNSVNVESGNVARFTCTATGRPEP 322
G+Y C N G + + V D PS + + + G+ C G P P
Sbjct: 1601 GKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAP 1660
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG--- 379
+ W+ +G R + + T +G L+I+ + +D VCSA + AG
Sbjct: 1661 EVSWTKDGERI-----STTRRIRQTQDENGNCKLSISKAE-SDDMGVYVCSATSVAGVDS 1714
Query: 380 -SSFVR-GKLT---------VTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTAICTPE 426
SS V K T T+D+ P T P + + + F A+ P+
Sbjct: 1715 TSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPS-LIEVNESGQFTLIAKAVGEPK 1773
Query: 427 PIIAWYFEGEALIQNHR---RNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P + W +G +++ +R VT DG L+ + + SG ++C A + +G +
Sbjct: 1774 PTVTWLKDGREILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQ 1833
Query: 482 LLVD--SPIN--PNI---HFFRAADVSSLPGPPTKPITHNVTDT-SVTLSW 524
++V P N N+ D+ + G PT ++ NVT + TL W
Sbjct: 1834 VIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPT-TLSCNVTGSPEPTLEW 1883
Score = 68.1 bits (159), Expect = 4e-11
Identities = 100/393 (25%), Positives = 148/393 (37%), Gaps = 52/393 (13%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG----LFFLRATHGRVHSDAGVYWCE 86
+ C P +I W + V ++ R + G L F+ T G D G Y CE
Sbjct: 2315 VECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPG----DEGTYACE 2370
Query: 87 ATNSYGTARSRNATLHVAVLREE--------FRLEP--ESKQSAQGDTVVLECLPPRGSP 136
A N G+A + N L V+ + FR E ++ G V L + S
Sbjct: 2371 AVNELGSAVT-NMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASE 2429
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
+ W +N T++ D S + L I D D G Y A+N +G A
Sbjct: 2430 PLQIRWLRNKVTIV-DSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGI---ARC 2485
Query: 195 TLKIHIK----------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
T+++ ++ P + + G SV + +V G P P + W ++ N
Sbjct: 2486 TMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNN 2545
Query: 245 PLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP-------PS 294
+ + ++G LR+ NV AD G+Y A N G +A LTV P
Sbjct: 2546 E-EKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPK 2604
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
N SP SV N A + +G P P W GN I G+ D Y T+ D +
Sbjct: 2605 FNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELI--DGL--DGYTITS-SDTNS 2659
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
L IN DK +C+ N G +
Sbjct: 2660 SLLINSVDKKHF-GEYLCTIRNQNGEELANAMI 2691
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/201 (27%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Query: 6 VTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
+ +AP + ++ P V + TL C G+P P I+W K + +++ +
Sbjct: 773 IDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDD-KPIDMSNKQVRHEN 831
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-LHVAVLREEFR---LEP-ESKQS 119
G+ L R D G Y CEA N +G A+S + + AV ++ R LEP + +
Sbjct: 832 GVCTLHIIGAR-DDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCST 890
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177
+G+ +VLEC G P P + W K+G L+ + + G L I + D G
Sbjct: 891 CEGNEMVLECC-VTGKPIPTITWYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGE 949
Query: 178 YQCIARNAAGTRESAIATLKI 198
Y C A N+ G ++ T+K+
Sbjct: 950 YTCEAVNSLG-KDFTHCTVKV 969
Score = 62.1 bits (144), Expect = 2e-09
Identities = 70/318 (22%), Positives = 126/318 (39%), Gaps = 33/318 (10%)
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
+R+ + +R ++ +I +P ++T P D G+ + V G P P + W
Sbjct: 984 SRSRSRSRSPSVVGGEIQ-RPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHD-- 1040
Query: 241 GGNMPLGR-VKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPS-- 294
G + R ++ DG + + A E G+Y C+ N +GAV + V P +
Sbjct: 1041 GKLVAESRTLRTYFDGRVAFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAE 1100
Query: 295 -INLSPNSVNV-------ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
+ P V +G A FTC + P + W G ++ Y
Sbjct: 1101 HVTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKAL----QQTKSNYK- 1155
Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR------PPPII 400
T +FD T + + ++ T A N G +LT++ + + P II
Sbjct: 1156 TRLFDDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFII 1215
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDL 457
P + ++++ +P P + W + L+++ R + DG L+++D+
Sbjct: 1216 ELKPKINVVEGATLSI-QADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDV 1274
Query: 458 DKSDSGTYTCVASSRHGK 475
D GTYT A + GK
Sbjct: 1275 GLEDEGTYTITAENEKGK 1292
Score = 62.1 bits (144), Expect = 2e-09
Identities = 106/502 (21%), Positives = 180/502 (35%), Gaps = 60/502 (11%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L G+P P + W K G+++ + SI G ++L H D G Y C A N+
Sbjct: 2202 LKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVHHVSTF-DKGFYNCTAANN 2260
Query: 91 YG--TARSRNATLH------VAVLREEFRLE----------PESKQSAQGDTVVLECLPP 132
G T S L V + + R E P Q+ +++ +EC
Sbjct: 2261 EGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEVLPGRSQANLNESLCVEC-SV 2319
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRE 190
P ++ W +N LL D DG +L D G Y C A N G+
Sbjct: 2320 SAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAV 2379
Query: 191 SAIATLKIHIKPYLITGPEDVV----------AQTGSSVTFQCRV--GGDPLPDVLWRRS 238
+ + + P G + GS V + +PL + W R+
Sbjct: 2380 TNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPL-QIRWLRN 2438
Query: 239 AGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----- 291
+ + + L + +V D GEY+ EA+N G + L V +
Sbjct: 2439 KVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSV 2498
Query: 292 ----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P + P + + + G G P+P + W+ G + + +KY
Sbjct: 2499 ADEAPRVFDFEPTTRS-DPGVSVELRAKVIGHPDPVISWTKAGQKL-----NNEEKYMMR 2552
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR--PPPIITNGPS 405
D + N T + + + +A+N +G + +LTV P P
Sbjct: 2553 NEGDKFILRIANVTRADAGKYEL--TAINPSGQANAELELTVVQSTKTVGAKPKFNESPI 2610
Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-HRRNVTNDGT---LVLKDLDKSD 461
+ K+ A + TP P W++ G LI +T+ T L++ +DK
Sbjct: 2611 SVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKKH 2670
Query: 462 SGTYTCVASSRHGKYVWSGALL 483
G Y C +++G+ + + +L
Sbjct: 2671 FGEYLCTIRNQNGEELANAMIL 2692
Score = 59.7 bits (138), Expect = 1e-08
Identities = 108/529 (20%), Positives = 185/529 (34%), Gaps = 59/529 (11%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
+IIE + V ++ GSP P + W K +V ++ R + G+ +
Sbjct: 1213 FIIELKPKINVVEGATLSIQADLNGSPIPEVVWLKDNSELV-ESDRIQMKCDGVNYQLLV 1271
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
D G Y A N G R +N + V +E + + E K+ + D + P
Sbjct: 1272 RDVGLEDEGTYTITAENEKGKIR-QNTEVSVTKSKE-VKEKKEKKKVEKKDEGKKKPGRP 1329
Query: 133 RGSPEPNVYWKKNGQTLLFDGDS---------------RMHLVDGGN-----LVIQDARQ 172
G P P+ K T+ FD S + V G+ L I+
Sbjct: 1330 -GLPRPSGASKTEQVTMAFDAPSEGPADSYEVERRCPDQREWVSCGSTKSLELEIKGLTP 1388
Query: 173 TDAGRYQCIARNAAGTRE-----SAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVG 226
++ +N G E S + T + P P+ ++A
Sbjct: 1389 NTEYIFRVAGKNKQGLGEWSEMTSTLKTASVGQAPQFTISPQSKIIANRDDEFEIAVEFS 1448
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE-GEYSCEAENSVGAVSASG 285
G P P V W + +P ++ V + + N+ +E G ++C EN +G SAS
Sbjct: 1449 GTPTPSVKWYKE-NLQIVPDEKIDVATTSTSSILNLKSQEENGTFNCLIENELGQASASC 1507
Query: 286 YLTVYDPPSI-----------NLSP------NSVNVESGNVARFTCTATGRPEPTMFWSV 328
+T+++ P+ NL P N+ + ++G TC + R E T+ W
Sbjct: 1508 QVTIFNKPASLQSTPDHSLERNLVPTLQKALNNESAQAGQQIMLTCRISSRSESTVAWFK 1567
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
+ R S +Y ++ L + D+ C N G + +
Sbjct: 1568 DDERI-----ESAGRYELSSDKKSNHKLVCHAVQSQDT-GKYRCVVTNKYGYAESECNVA 1621
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
V P + S+ T + C +P P ++W +GE + R T
Sbjct: 1622 VEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQ 1681
Query: 449 DGT----LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
D L + + D G Y C A+S G S +++ + H
Sbjct: 1682 DENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSH 1730
Score = 58.8 bits (136), Expect = 2e-08
Identities = 75/322 (23%), Positives = 109/322 (33%), Gaps = 39/322 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAG 64
VT AP D T TL C+ GSP+P + W K G + + R
Sbjct: 1625 VTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQDEN 1684
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGT---------ARSRNATLHVAVL--------R 107
G L + D GVY C AT+ G A++ H+ + +
Sbjct: 1685 GNCKLSISKAE-SDDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSHLVIAQTADEKHEK 1743
Query: 108 EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GN 164
F P S G P+P V W K+G+ +L H V G +
Sbjct: 1744 PRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKDGREILRTNRIYHHFVTGDGESH 1803
Query: 165 LVIQDARQTDAGRYQCIARNAAGT--RESAIATLKI-------HIKPYLITGPEDVVAQT 215
L+ + +G + C A N GT E+ + ++ ++ P D+
Sbjct: 1804 LIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVN 1863
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--------DGSLRLDNVILADE 267
G T C V G P P + W G+ D L+ + V+
Sbjct: 1864 GHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQR 1923
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A NS G + YL V
Sbjct: 1924 GTYQCIATNSSGQATTQCYLLV 1945
Score = 58.8 bits (136), Expect = 2e-08
Identities = 91/415 (21%), Positives = 163/415 (39%), Gaps = 54/415 (13%)
Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
V R +F ++P+ ++ + + G+P P V+W K G ++ + ++ + + G+
Sbjct: 2179 VCRPKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEG--IILETGNKYSIYNDGD 2236
Query: 165 ---LVIQDARQTDAGRYQCIARNAAG------------TRESAIATL-------KIHIKP 202
L + D G Y C A N G +E + A + +
Sbjct: 2237 FYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPN 2296
Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRL 259
++ P A S+ +C V P ++W R++ R + DG SL+
Sbjct: 2297 FIEVLPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKF 2356
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSP--------NSV-NVESGN 308
+V DEG Y+CEA N +G+ + L V DP + P SV V G+
Sbjct: 2357 ISVTPGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGS 2416
Query: 309 VARFTCTATGRPEPTMFWSVEGNRTII-FPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
EP + TI+ P S + + + LTI D D
Sbjct: 2417 RVELAAELVQASEPLQIRWLRNKVTIVDSPSFSYSR------SENMVFLTIADVFPEDGG 2470
Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDD----DRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
V A N +G + +L V +++ D P + P+ ++ P S+ + I
Sbjct: 2471 EYTV-EAKNQSGIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVEL-RAKVIG 2528
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGK 475
P+P+I+W G+ L + + N+G L + ++ ++D+G Y A + G+
Sbjct: 2529 HPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQ 2583
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
Query: 209 EDVVAQTGSSV-TFQCRVGGDPLPDVLWRRSAGGGNMPLGRV-KVLDDG--SLRLDNVIL 264
ED+VA G + T C V G P P V W + +P + ++G L + N++
Sbjct: 449 EDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVE 508
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV 289
+D G+Y+C A N +G++ L+V
Sbjct: 509 SDAGKYTCRATNDLGSIMTHAKLSV 533
Score = 37.9 bits (84), Expect = 0.043
Identities = 44/189 (23%), Positives = 69/189 (36%), Gaps = 21/189 (11%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV--- 76
D+ + P TL+C GSP P + W + + H+ L + + G+V
Sbjct: 1858 DMGIVNGHPTTLSCNVTGSPEPTLEW----IYIDDSGHKINLTSSTTDWTECRFGKVAEL 1913
Query: 77 ------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE-- 128
G Y C ATNS G A ++ L V L +E P + Q L+
Sbjct: 1914 KSERVLREQRGTYQCIATNSSGQATTQ-CYLLVGELSDEPAGPPRFVKCLQDTWTPLKES 1972
Query: 129 ---CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIAR 183
+ G P P++ W N + + D ++ L I++ G Y A
Sbjct: 1973 IEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEAS 2032
Query: 184 NAAGTRESA 192
N G +A
Sbjct: 2033 NIHGVLRTA 2041
Score = 37.1 bits (82), Expect = 0.076
Identities = 28/111 (25%), Positives = 52/111 (46%), Gaps = 11/111 (9%)
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
R A +R + K +KP P V+ + S+ + + G+P+P V W + G
Sbjct: 2169 RAAINSRNKRVCRPKFMVKPK----PRKVLEEY-KSLRLKTAISGNPMPQVHWDKE--GI 2221
Query: 243 NMPLG-RVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+ G + + +DG L + +V D+G Y+C A N+ G ++ + + V
Sbjct: 2222 ILETGNKYSIYNDGDFYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDV 2272
Score = 34.7 bits (76), Expect = 0.40
Identities = 22/83 (26%), Positives = 42/83 (50%), Gaps = 2/83 (2%)
Query: 569 QTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRN 628
Q + +L+PG +Y F VR +N+ G S PS S+ V V + S + E + +
Sbjct: 17 QAFITLFNLVPGESYRFRVRADNTFGQSEPSDESELVVVKNVSRVVEEPKKKEVKVKEQE 76
Query: 629 NILTDHIVELIEATPIDSKTIKL 651
++ + + + ++ P + KTI +
Sbjct: 77 SVDYERVAK--DSEPSEYKTIDI 97
Score = 34.3 bits (75), Expect = 0.53
Identities = 15/43 (34%), Positives = 19/43 (44%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG 49
T G P E P+ V A L G+P+PA RW+ G
Sbjct: 2598 TVGAKPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNG 2640
Score = 33.5 bits (73), Expect = 0.93
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRR--NVTNDGT--LVLKDLDKSDSGTYTCVA 469
+A C P P + WY + + L + + N+G L +K++ +SD+G YTC A
Sbjct: 459 IATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRA 518
Query: 470 SSRHGKYVWSGALLV 484
++ G + L V
Sbjct: 519 TNDLGSIMTHAKLSV 533
Score = 33.1 bits (72), Expect = 1.2
Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 2/69 (2%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQ 179
GD + G P P V W K+ + L + G L +++ ++DAG+Y
Sbjct: 456 GDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYT 515
Query: 180 CIARNAAGT 188
C A N G+
Sbjct: 516 CRATNDLGS 524
>AY130758-2|AAN61518.1| 18519|Caenorhabditis elegans 2MDa_2 protein
protein.
Length = 18519
Score = 106 bits (255), Expect = 8e-23
Identities = 134/531 (25%), Positives = 210/531 (39%), Gaps = 59/531 (11%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFL 69
AP +Q DV + L +P+P I W++ + S HR G +
Sbjct: 16481 APSFGKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYS 16540
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-----------FRLE-PESK 117
D+G Y C A N G A + +L + FR++ P +
Sbjct: 16541 LTIIDAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPR 16600
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177
+ QG + L C G+P PN+ W K+ + + H L I AR D GR
Sbjct: 16601 EVPQGADLTLVC-SVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGARDDDQGR 16659
Query: 178 YQCIARNAAGTRES------AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
Y C A N G +S A K H++P + + G+ + +C V G P+P
Sbjct: 16660 YVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIP 16719
Query: 232 DVLWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLT 288
+ W + + ++ D G RL+ NV++ D+GEY+CEA NS+G +
Sbjct: 16720 TITWYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVK 16779
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATG---RP----EPTMFWSV-EGNRTII----- 335
V D V S + +R G RP P +V EGNR ++
Sbjct: 16780 VVDMGLSKTRLTPVRSRSRSRSRSPSVVGGEIQRPPVVTRPLADATVTEGNRELLEVEVD 16839
Query: 336 -FPGMSRDKYH----------ATAVFDG-VTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
FP + + YH FDG V L I + + + VC N G+
Sbjct: 16840 GFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKIYEAHE-EHNGQYVCKVSNKLGAVET 16898
Query: 384 RGKLTVTSDD--DRPPPIITNGPSNQTLPIKS---MAVFPCTAICTPEPIIAWYFEGEAL 438
R + V + D + + T Q + +K+ A F C + P + W G+AL
Sbjct: 16899 RAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKAL 16958
Query: 439 IQ---NHRRNVTND--GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
Q N++ + +D TLV++++ GTYT VA+++ G S L +
Sbjct: 16959 QQTKSNYKTRLFDDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTI 17009
Score = 103 bits (246), Expect = 1e-21
Identities = 124/505 (24%), Positives = 180/505 (35%), Gaps = 52/505 (10%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
Q L CR + W+K + S + H D G Y C
Sbjct: 17358 QQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQDTGKYRCV 17417
Query: 87 ATNSYGTARSR-NATLH--VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
TN YG A S N + + F + G + LEC GSP P V W
Sbjct: 17418 VTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLEC-KVEGSPAPEVSWT 17476
Query: 144 KNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKI- 198
K+G+ + R + GN L I A D G Y C A + AG + S + K
Sbjct: 17477 KDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSSMVMIAKTT 17536
Query: 199 ---------------HIKPYLITGPEDVVAQTGSS-VTFQCRVGGDPLPDVLWRRSAGGG 242
H KP P ++ S T + G+P P V W + G
Sbjct: 17537 GTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKD-GRE 17595
Query: 243 NMPLGRVK---VLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291
+ R+ V DG L + V+ G +SC+AEN G V A + V
Sbjct: 17596 ILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPANQ 17655
Query: 292 ----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV--EGNRTIIFPGMSRDKYH 345
P + + + +G+ +C TG PEPT+ W + I + D
Sbjct: 17656 LANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTD--W 17713
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--TSDDDRPPPIITNG 403
F V L ++ + R T C A N +G + + L V SD+ PP
Sbjct: 17714 TECRFGKVAELK-SERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPAGPPRFVKC 17772
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLVL--KDLDK 459
+ P+K F P P + WY + + + +T +D T VL K++
Sbjct: 17773 LQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIKNVSL 17832
Query: 460 SDSGTYTCVASSRHGKYVWSGALLV 484
+ G Y AS+ HG +G L V
Sbjct: 17833 ASLGMYFVEASNIHGVLRTAGRLNV 17857
Score = 89.4 bits (212), Expect = 1e-17
Identities = 130/511 (25%), Positives = 194/511 (37%), Gaps = 74/511 (14%)
Query: 29 ATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
ATL+C G PSP ++WYK L V GL L V SDAG Y C A
Sbjct: 16271 ATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAEL-TVKNIVESDAGKYTCRA 16329
Query: 88 TNSYGTARSRNATLHVAV---LREEFRLEP----ESKQSAQGDTVVLE---CLPPR---- 133
TN G+ + +A L V +++ + P + K VV+E +PP
Sbjct: 16330 TNDLGSIMT-HAKLSVKADEKKKKKSKTSPAVIEKKKDRKTSKVVVIEEMIDMPPNFHHL 16388
Query: 134 --------GSP-----------EPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQ 172
G P EP V W NG+ + + + + D G L I
Sbjct: 16389 LQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYLRKHDKGRYELHILSVDS 16448
Query: 173 TDAGRYQCIARNAAGTRES-AIATLKIHIKPYLIT-GPE--DVVAQTGSSVTFQCRVGGD 228
TD G+++ + +NA G ES A T+ I Y + G + DV + + + +
Sbjct: 16449 TDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGKQLSDVKCSESDILKLEVNIQAN 16508
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSAS 284
P P++ W R+ DDG SL + + D GEY C A+N +G
Sbjct: 16509 PAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYAEDSGEYKCVAKNKIGKAHTV 16568
Query: 285 GYLTVYD-------------PPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
+ + + P + P V G C+ +G P P + W+ +
Sbjct: 16569 CCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWT-KD 16627
Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG--SSFVRGKLT 388
++ I MS + +GV L I ++D + VC A N G SF ++
Sbjct: 16628 DKPI---DMSNKQVRHE---NGVCTLHIIGA-RDDDQGRYVCEAENIHGVAQSFSVVEIK 16680
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
D D P N + + V C P P I WY +G LI +R
Sbjct: 16681 EAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQYT 16740
Query: 449 D----GTLVLKDLDKSDSGTYTCVASSRHGK 475
D L + ++ +D G YTC A + GK
Sbjct: 16741 DRKGVSRLNIMNVVMNDDGEYTCEAVNSLGK 16771
Score = 88.2 bits (209), Expect = 3e-17
Identities = 127/555 (22%), Positives = 211/555 (38%), Gaps = 92/555 (16%)
Query: 9 GEAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G+AP P +A R + G+P+P+++WYK + +V D +
Sbjct: 17231 GQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVATTSTSS 17290
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PE---------- 115
L + + G + C N G A +A+ V + + L+ P+
Sbjct: 17291 ILNL---KSQEENGTFNCLIENELGQA---SASCQVTIFNKPASLQSTPDHSLERNLVPT 17344
Query: 116 -----SKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVI 167
+ +SAQ G ++L C S E V W K+ + + G + N LV
Sbjct: 17345 LQKALNNESAQAGQQIMLTCRISSRS-ESTVAWFKDDERIESAGRYELSSDKKSNHKLVC 17403
Query: 168 QDARQTDAGRYQCIARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
+ D G+Y+C+ N G ES A+ + I P D A G ++T +C
Sbjct: 17404 HAVQSQDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLEC 17463
Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVG 279
+V G P P+V W + G R++ D + L + D G Y C A + G
Sbjct: 17464 KVEGSPAPEVSWTKD-GERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAG 17522
Query: 280 AVSASGYLTV-------------------YDPPSINLSPNSVNVESGNVARFT--CTATG 318
S S + + ++ P +P S+ +E +FT A G
Sbjct: 17523 VDSTSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSL-IEVNESGQFTLIAKAVG 17581
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
P+PT+ W +G + + YH DG + L I + + + C A N
Sbjct: 17582 EPKPTVTWLKDGREIL----RTNRIYHHFVTGDGESHL-IAECVVSKTSGIFSCKAENPN 17636
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV---FPCTAIC----TPEPIIAW 431
G+ V + V +P + N T+P+ M + P T C +PEP + W
Sbjct: 17637 GT--VIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEW 17694
Query: 432 YFEGEALIQNHRRNVTNDGT------------LVLKDLDKSDSGTYTCVASSRHGKYVWS 479
+ ++ H+ N+T+ T L + + + GTY C+A++ G+
Sbjct: 17695 IYIDDS---GHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQ 17751
Query: 480 GALLV----DSPINP 490
LLV D P P
Sbjct: 17752 CYLLVGELSDEPAGP 17766
Score = 84.6 bits (200), Expect = 4e-16
Identities = 115/510 (22%), Positives = 200/510 (39%), Gaps = 73/510 (14%)
Query: 39 PSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
P P + WY G + ++D++ G + L +D G + N++G S
Sbjct: 16410 PEPTVDWYHNGEHISINDSNYLRKHDKGRYELHILSVD-STDEGKWKAVGKNAFGECESE 16468
Query: 98 NATLHVAV----LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG 153
A L V + F + + ++ D + LE + + +P P + W +N +
Sbjct: 16469 -AKLTVVIPDGQYAPSFGKQLSDVKCSESDILKLE-VNIQANPAPEINWFRNESEIEHSQ 16526
Query: 154 DSRMHLVDG-GN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH----IKPYLIT 206
R+ DG GN L I DA D+G Y+C+A+N G + + ++I + I
Sbjct: 16527 HHRLQFDDGSGNYSLTIIDAYAEDSGEYKCVAKNKIG-KAHTVCCVRIEELLSKRSKKID 16585
Query: 207 G----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG- 255
G P G+ +T C V G P P++ W + +M +V+ ++G
Sbjct: 16586 GSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVR-HENGV 16644
Query: 256 -SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--------PPSINLSPNSVNVES 306
+L + D+G Y CEAEN G + + + + P + N E
Sbjct: 16645 CTLHIIGARDDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCE- 16703
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
GN C TG+P PT+ W +G + II ++ GV+ L I + ND
Sbjct: 16704 GNEMVLECCVTGKPIPTITWYKDGLKLII-----ENRMLQYTDRKGVSRLNIMNVVMNDD 16758
Query: 367 RNTIVCSAVNYAGSSFV------------RGKLT--------------VTSDDDRPPPII 400
C AVN G F + +LT V + + PP++
Sbjct: 16759 -GEYTCEAVNSLGKDFTHCTVKVVDMGLSKTRLTPVRSRSRSRSRSPSVVGGEIQRPPVV 16817
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDL 457
T ++ T+ + + P P I WY +G+ + ++ DG L + +
Sbjct: 16818 TRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKIYEA 16877
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ +G Y C S++ G ++V++P
Sbjct: 16878 HEEHNGQYVCKVSNKLGAVETRAIVVVEAP 16907
Score = 81.0 bits (191), Expect = 5e-15
Identities = 80/335 (23%), Positives = 142/335 (42%), Gaps = 19/335 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAG 64
V + +AP +++ V + + L C A G P+P WYK G ++ +D + I+ G
Sbjct: 14445 VLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKDGKEIIPTDENTEIVNEG 14504
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGD 123
+ L H D G+Y N +GTA S A + ++ +R F E + +G
Sbjct: 14505 SMSAL-IIHELAGEDVGLYKVLVENIHGTAES-EAEVGISDVRAHFNSSFSELTEIEEGH 14562
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIA 182
+ L C E V W K+G+ L+ + + + L I+ + D+G Y+C
Sbjct: 14563 DIELTC--EVSDEEAVVNWYKDGKKLVASDRVQFYAMARKRTLRIKGSTDADSGVYKCET 14620
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
+ E + + +P+++ GP+D +V G ++ C P+ V W ++
Sbjct: 14621 TDGRSRTEGEV--IVNEQEPHILVGPQDAIVKDFGETMVLFCET-SKPVRKVKWFKNGVE 14677
Query: 242 GNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
+ + + +DG +L + N D G Y+ A S SA L P++ +
Sbjct: 14678 IWPQMNKAIMENDGKRATLEIKNFDKHDIGAYT--ASVSEKETSAPAKLVFEVAPNLIIP 14735
Query: 299 P---NSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
+ V V +GN F +G P PT+ + G
Sbjct: 14736 TEIRDGVTVHAGNEFDFAVEFSGFPIPTIHLTNNG 14770
Score = 79.8 bits (188), Expect = 1e-14
Identities = 82/338 (24%), Positives = 132/338 (39%), Gaps = 27/338 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P ++ +PL D TV L G P+P I WY G LV G + F
Sbjct: 16812 QRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAF 16871
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSR--------NATLHVAVLREEFRLEPESKQSA 120
L+ + G Y C+ +N G +R +A HV + + +
Sbjct: 16872 LKIYEAHEEHN-GQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 16930
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDG--GNLVIQDARQTDAGR 177
G+T C +P V W NG+ L + + L D LVI++ G
Sbjct: 16931 AGETATFTC-QSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGT 16989
Query: 178 YQCIARNAAG-TRESAIATL------KIHIK-PYLITGPEDVV-AQTGSSVTFQCRVGGD 228
Y +A N G SA T+ KI PY I + + G++++ Q + G
Sbjct: 16990 YTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGS 17049
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P+P+V+W + + R+++ DG L + +V L DEG Y+ AEN G + +
Sbjct: 17050 PIPEVVWLKD-NSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNT 17108
Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
++V + VE + + G P P+
Sbjct: 17109 EVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPS 17146
Score = 68.1 bits (159), Expect = 4e-11
Identities = 106/471 (22%), Positives = 178/471 (37%), Gaps = 66/471 (14%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F + P+SK A D + G+P P+V W K + L D ++ + I
Sbjct: 17235 QFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYK--ENLQIVPDEKIDVATTSTSSIL 17292
Query: 169 DAR-QTDAGRYQCIARNAAGTRESAIA----------------TLKIHIKPYLITGPEDV 211
+ + Q + G + C+ N G ++ +L+ ++ P L +
Sbjct: 17293 NLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKALNNE 17352
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
AQ G + CR+ V W R G L K + L V D
Sbjct: 17353 SAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDK-KSNHKLVCHAVQSQDT 17411
Query: 268 GEYSCEAENSVGAVSASGYLTVYD-----PPSINLSPNSVNVESGNVARFTCTATGRPEP 322
G+Y C N G + + V D PS + + + G+ C G P P
Sbjct: 17412 GKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAP 17471
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG--- 379
+ W+ +G R + + T +G L+I+ + +D VCSA + AG
Sbjct: 17472 EVSWTKDGERI-----STTRRIRQTQDENGNCKLSISKAE-SDDMGVYVCSATSVAGVDS 17525
Query: 380 -SSFVR-GKLT---------VTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTAICTPE 426
SS V K T T+D+ P T P + + + F A+ P+
Sbjct: 17526 TSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPS-LIEVNESGQFTLIAKAVGEPK 17584
Query: 427 PIIAWYFEGEALIQNHR---RNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P + W +G +++ +R VT DG L+ + + SG ++C A + +G +
Sbjct: 17585 PTVTWLKDGREILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQ 17644
Query: 482 LLVD--SPIN--PNI---HFFRAADVSSLPGPPTKPITHNVTDT-SVTLSW 524
++V P N N+ D+ + G PT ++ NVT + TL W
Sbjct: 17645 VIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPT-TLSCNVTGSPEPTLEW 17694
Score = 68.1 bits (159), Expect = 4e-11
Identities = 100/393 (25%), Positives = 148/393 (37%), Gaps = 52/393 (13%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG----LFFLRATHGRVHSDAGVYWCE 86
+ C P +I W + V ++ R + G L F+ T G D G Y CE
Sbjct: 18126 VECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPG----DEGTYACE 18181
Query: 87 ATNSYGTARSRNATLHVAVLREE--------FRLEP--ESKQSAQGDTVVLECLPPRGSP 136
A N G+A + N L V+ + FR E ++ G V L + S
Sbjct: 18182 AVNELGSAVT-NMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASE 18240
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
+ W +N T++ D S + L I D D G Y A+N +G A
Sbjct: 18241 PLQIRWLRNKVTIV-DSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGI---ARC 18296
Query: 195 TLKIHIK----------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
T+++ ++ P + + G SV + +V G P P + W ++ N
Sbjct: 18297 TMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNN 18356
Query: 245 PLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP-------PS 294
+ + ++G LR+ NV AD G+Y A N G +A LTV P
Sbjct: 18357 E-EKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPK 18415
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
N SP SV N A + +G P P W GN I G+ D Y T+ D +
Sbjct: 18416 FNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELI--DGL--DGYTITS-SDTNS 18470
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
L IN DK +C+ N G +
Sbjct: 18471 SLLINSVDKKHF-GEYLCTIRNQNGEELANAMI 18502
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/201 (27%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Query: 6 VTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
+ +AP + ++ P V + TL C G+P P I+W K + +++ +
Sbjct: 16584 IDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDD-KPIDMSNKQVRHEN 16642
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-LHVAVLREEFR---LEP-ESKQS 119
G+ L R D G Y CEA N +G A+S + + AV ++ R LEP + +
Sbjct: 16643 GVCTLHIIGAR-DDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCST 16701
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177
+G+ +VLEC G P P + W K+G L+ + + G L I + D G
Sbjct: 16702 CEGNEMVLECC-VTGKPIPTITWYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGE 16760
Query: 178 YQCIARNAAGTRESAIATLKI 198
Y C A N+ G ++ T+K+
Sbjct: 16761 YTCEAVNSLG-KDFTHCTVKV 16780
Score = 62.1 bits (144), Expect = 2e-09
Identities = 70/318 (22%), Positives = 126/318 (39%), Gaps = 33/318 (10%)
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
+R+ + +R ++ +I +P ++T P D G+ + V G P P + W
Sbjct: 16795 SRSRSRSRSPSVVGGEIQ-RPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHD-- 16851
Query: 241 GGNMPLGR-VKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPS-- 294
G + R ++ DG + + A E G+Y C+ N +GAV + V P +
Sbjct: 16852 GKLVAESRTLRTYFDGRVAFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAE 16911
Query: 295 -INLSPNSVNV-------ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
+ P V +G A FTC + P + W G ++ Y
Sbjct: 16912 HVTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKAL----QQTKSNYK- 16966
Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR------PPPII 400
T +FD T + + ++ T A N G +LT++ + + P II
Sbjct: 16967 TRLFDDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFII 17026
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDL 457
P + ++++ +P P + W + L+++ R + DG L+++D+
Sbjct: 17027 ELKPKINVVEGATLSI-QADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDV 17085
Query: 458 DKSDSGTYTCVASSRHGK 475
D GTYT A + GK
Sbjct: 17086 GLEDEGTYTITAENEKGK 17103
Score = 62.1 bits (144), Expect = 2e-09
Identities = 106/502 (21%), Positives = 180/502 (35%), Gaps = 60/502 (11%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L G+P P + W K G+++ + SI G ++L H D G Y C A N+
Sbjct: 18013 LKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVHHVSTF-DKGFYNCTAANN 18071
Query: 91 YG--TARSRNATLH------VAVLREEFRLE----------PESKQSAQGDTVVLECLPP 132
G T S L V + + R E P Q+ +++ +EC
Sbjct: 18072 EGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEVLPGRSQANLNESLCVEC-SV 18130
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRE 190
P ++ W +N LL D DG +L D G Y C A N G+
Sbjct: 18131 SAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAV 18190
Query: 191 SAIATLKIHIKPYLITGPEDVV----------AQTGSSVTFQCRV--GGDPLPDVLWRRS 238
+ + + P G + GS V + +PL + W R+
Sbjct: 18191 TNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPL-QIRWLRN 18249
Query: 239 AGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----- 291
+ + + L + +V D GEY+ EA+N G + L V +
Sbjct: 18250 KVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSV 18309
Query: 292 ----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P + P + + + G G P+P + W+ G + + +KY
Sbjct: 18310 ADEAPRVFDFEPTTRS-DPGVSVELRAKVIGHPDPVISWTKAGQKL-----NNEEKYMMR 18363
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR--PPPIITNGPS 405
D + N T + + + +A+N +G + +LTV P P
Sbjct: 18364 NEGDKFILRIANVTRADAGKYEL--TAINPSGQANAELELTVVQSTKTVGAKPKFNESPI 18421
Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-HRRNVTNDGT---LVLKDLDKSD 461
+ K+ A + TP P W++ G LI +T+ T L++ +DK
Sbjct: 18422 SVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKKH 18481
Query: 462 SGTYTCVASSRHGKYVWSGALL 483
G Y C +++G+ + + +L
Sbjct: 18482 FGEYLCTIRNQNGEELANAMIL 18503
Score = 59.7 bits (138), Expect = 1e-08
Identities = 108/529 (20%), Positives = 185/529 (34%), Gaps = 59/529 (11%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
+IIE + V ++ GSP P + W K +V ++ R + G+ +
Sbjct: 17024 FIIELKPKINVVEGATLSIQADLNGSPIPEVVWLKDNSELV-ESDRIQMKCDGVNYQLLV 17082
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
D G Y A N G R +N + V +E + + E K+ + D + P
Sbjct: 17083 RDVGLEDEGTYTITAENEKGKIR-QNTEVSVTKSKE-VKEKKEKKKVEKKDEGKKKPGRP 17140
Query: 133 RGSPEPNVYWKKNGQTLLFDGDS---------------RMHLVDGGN-----LVIQDARQ 172
G P P+ K T+ FD S + V G+ L I+
Sbjct: 17141 -GLPRPSGASKTEQVTMAFDAPSEGPADSYEVERRCPDQREWVSCGSTKSLELEIKGLTP 17199
Query: 173 TDAGRYQCIARNAAGTRE-----SAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVG 226
++ +N G E S + T + P P+ ++A
Sbjct: 17200 NTEYIFRVAGKNKQGLGEWSEMTSTLKTASVGQAPQFTISPQSKIIANRDDEFEIAVEFS 17259
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE-GEYSCEAENSVGAVSASG 285
G P P V W + +P ++ V + + N+ +E G ++C EN +G SAS
Sbjct: 17260 GTPTPSVKWYKE-NLQIVPDEKIDVATTSTSSILNLKSQEENGTFNCLIENELGQASASC 17318
Query: 286 YLTVYDPPSI-----------NLSP------NSVNVESGNVARFTCTATGRPEPTMFWSV 328
+T+++ P+ NL P N+ + ++G TC + R E T+ W
Sbjct: 17319 QVTIFNKPASLQSTPDHSLERNLVPTLQKALNNESAQAGQQIMLTCRISSRSESTVAWFK 17378
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
+ R S +Y ++ L + D+ C N G + +
Sbjct: 17379 DDERI-----ESAGRYELSSDKKSNHKLVCHAVQSQDT-GKYRCVVTNKYGYAESECNVA 17432
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
V P + S+ T + C +P P ++W +GE + R T
Sbjct: 17433 VEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQ 17492
Query: 449 DGT----LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
D L + + D G Y C A+S G S +++ + H
Sbjct: 17493 DENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSH 17541
Score = 58.8 bits (136), Expect = 2e-08
Identities = 75/322 (23%), Positives = 109/322 (33%), Gaps = 39/322 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAG 64
VT AP D T TL C+ GSP+P + W K G + + R
Sbjct: 17436 VTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQDEN 17495
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGT---------ARSRNATLHVAVL--------R 107
G L + D GVY C AT+ G A++ H+ + +
Sbjct: 17496 GNCKLSISKAE-SDDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSHLVIAQTADEKHEK 17554
Query: 108 EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GN 164
F P S G P+P V W K+G+ +L H V G +
Sbjct: 17555 PRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKDGREILRTNRIYHHFVTGDGESH 17614
Query: 165 LVIQDARQTDAGRYQCIARNAAGT--RESAIATLKI-------HIKPYLITGPEDVVAQT 215
L+ + +G + C A N GT E+ + ++ ++ P D+
Sbjct: 17615 LIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVN 17674
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--------DGSLRLDNVILADE 267
G T C V G P P + W G+ D L+ + V+
Sbjct: 17675 GHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQR 17734
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A NS G + YL V
Sbjct: 17735 GTYQCIATNSSGQATTQCYLLV 17756
Score = 58.8 bits (136), Expect = 2e-08
Identities = 91/415 (21%), Positives = 163/415 (39%), Gaps = 54/415 (13%)
Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
V R +F ++P+ ++ + + G+P P V+W K G ++ + ++ + + G+
Sbjct: 17990 VCRPKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEG--IILETGNKYSIYNDGD 18047
Query: 165 ---LVIQDARQTDAGRYQCIARNAAG------------TRESAIATL-------KIHIKP 202
L + D G Y C A N G +E + A + +
Sbjct: 18048 FYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPN 18107
Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRL 259
++ P A S+ +C V P ++W R++ R + DG SL+
Sbjct: 18108 FIEVLPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKF 18167
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSP--------NSV-NVESGN 308
+V DEG Y+CEA N +G+ + L V DP + P SV V G+
Sbjct: 18168 ISVTPGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGS 18227
Query: 309 VARFTCTATGRPEPTMFWSVEGNRTII-FPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
EP + TI+ P S + + + LTI D D
Sbjct: 18228 RVELAAELVQASEPLQIRWLRNKVTIVDSPSFSYSR------SENMVFLTIADVFPEDGG 18281
Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDD----DRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
V A N +G + +L V +++ D P + P+ ++ P S+ + I
Sbjct: 18282 EYTV-EAKNQSGIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVEL-RAKVIG 18339
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGK 475
P+P+I+W G+ L + + N+G L + ++ ++D+G Y A + G+
Sbjct: 18340 HPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQ 18394
Score = 56.4 bits (130), Expect = 1e-07
Identities = 82/365 (22%), Positives = 137/365 (37%), Gaps = 46/365 (12%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P+ +P + + T TG P P + W N+ IF G K G
Sbjct: 15599 PAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFK--NKKEIFSG----KRQWIENIAG 15652
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI- 411
T LTI + ++D + N AGS KLT+ D+ P I TL
Sbjct: 15653 ATSLTIGEMREDDEGEYKIV-VKNTAGSVEHSCKLTM----DQLPEINRVDRYASTLVFD 15707
Query: 412 KSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYT 466
K V + P+P + W +I+ R+ + L + +D D G +
Sbjct: 15708 KGETVKLRLSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEFA 15767
Query: 467 CVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
+R G+ ++ + V+ P P KP + SV L W+
Sbjct: 15768 LKIKNRCGEDKYAIGI----------------QVTDRPAAPGKPAVEDQNVDSVRLRWAA 15811
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
G S + Y VE+ + + + W A Q + +L+PG +Y F
Sbjct: 15812 PTNDGGSPVRNYTVEMCTEK----------GKTWTK-AEVTKQAFITLFNLVPGESYRFR 15860
Query: 587 VRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDS 646
VR +N+ G S PS S+ V V + S + E + + ++ + + + ++ P +
Sbjct: 15861 VRADNTFGQSEPSDESELVVVKNVSRVVEEPKKKEVKVKEQESVDYERVAK--DSEPSEY 15918
Query: 647 KTIKL 651
KTI +
Sbjct: 15919 KTIDI 15923
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/177 (25%), Positives = 80/177 (45%), Gaps = 21/177 (11%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNAAGTRES 191
G P+P + W + L+ DG+ + G I+ + + G +C A N AG E+
Sbjct: 3814 GVPQPTISWLIDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCRATNCAGQVET 3873
Query: 192 A---IATLKIHI----------KPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+ +A +I + +P+ + PE V +T +C+ G PLP +W +
Sbjct: 3874 SCEIVAADEISVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEK 3933
Query: 238 SAGGGNMPLGRVKV-LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
G + L + +V +DG+ L++++ L D+ Y+C N G S S + V D
Sbjct: 3934 D--GVLLDLQKYQVTTEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDVVD 3988
Score = 55.2 bits (127), Expect = 3e-07
Identities = 78/358 (21%), Positives = 144/358 (40%), Gaps = 36/358 (10%)
Query: 134 GSPEPNVYWKKNGQTLLFD---GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G E V +K +G ++ G R +I R+ ++ ARN GT E
Sbjct: 14376 GEKEFVVQYKSDGSSIWASVDIGGPRSESAATSKCIIDGLREGIPYVFRVAARNQHGTGE 14435
Query: 191 SAIATLKIHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+ T+ + + P ++ + V + +C G P P+ +W + G +P
Sbjct: 14436 FSEPTIPVVVLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKD-GKEIIPT 14494
Query: 247 GR-VKVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSPNS 301
+++++GS+ + + D G Y EN G + + + D + N S +
Sbjct: 14495 DENTEIVNEGSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVRAHFNSSFSE 14554
Query: 302 VN-VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
+ +E G+ TC + E + W +G + + R +++A A + + D
Sbjct: 14555 LTEIEEGHDIELTCEVSDE-EAVVNWYKDGKKLV---ASDRVQFYAMARKRTLRIKGSTD 14610
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFP 418
D + C + G S G++ V + P I GP + + ++M +F
Sbjct: 14611 ADSGVYK----CETTD--GRSRTEGEVIVNEQE----PHILVGPQDAIVKDFGETMVLFC 14660
Query: 419 CTAICTPEPIIAWYFEG-EALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSR 472
T+ P + W+ G E Q ++ + NDG TL +K+ DK D G YT S +
Sbjct: 14661 ETS--KPVRKVKWFKNGVEIWPQMNKAIMENDGKRATLEIKNFDKHDIGAYTASVSEK 14716
Score = 54.4 bits (125), Expect = 5e-07
Identities = 45/171 (26%), Positives = 70/171 (40%), Gaps = 12/171 (7%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSL 257
KP P D+ A G P P++ W ++ G + SL
Sbjct: 15598 KPAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIE-NIAGATSL 15656
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN---LSPNSVNVESGNVARFTC 314
+ + DEGEY +N+ G+V S LT+ P IN +++ + G +
Sbjct: 15657 TIGEMREDDEGEYKIVVKNTAGSVEHSCKLTMDQLPEINRVDRYASTLVFDKGETVKLRL 15716
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
+ +GRP+P + W ++ N +I SR V + TVLTIN D D
Sbjct: 15717 SFSGRPQPEVIW-IDNNGKVI--EESRKMKIEKTVLN--TVLTINSIDSQD 15762
Score = 53.6 bits (123), Expect = 8e-07
Identities = 78/323 (24%), Positives = 121/323 (37%), Gaps = 21/323 (6%)
Query: 86 EATNSYGTARSRNATLHVAVLREEF-RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
E T + GT S L V L +F + P +G V + V W K
Sbjct: 13943 EITATCGT-ESHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVVWLK 14001
Query: 145 NGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
+G+ L + D + V +L ++ A+ D+G+Y+ + L I KP
Sbjct: 14002 DGKPLEINKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDGV-----DCSTHLSIQGKPV 14056
Query: 204 LITGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDG-SLR 258
L E V F V D P+ + + G ++ R+ V+DDG L
Sbjct: 14057 LKNVSETKPVITVDKDDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDDGLKLT 14116
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
V D GEY + +N G V+ + V D PS +P V+V A C
Sbjct: 14117 KRGVSKTDAGEYEVKLKNEFGEVAQKFDVKVNDTPS---APGDVSVVK---AESDCLHIE 14170
Query: 319 RPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
PT E +I S R K+H A +G + D + ++ + +AVN
Sbjct: 14171 WTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNK 14230
Query: 378 AGS-SFVRGKLTVTSDDDRPPPI 399
G+ F+ K T + P +
Sbjct: 14231 FGTGEFIETKPVQTGSPFQVPTV 14253
Score = 50.4 bits (115), Expect = 8e-06
Identities = 71/285 (24%), Positives = 111/285 (38%), Gaps = 25/285 (8%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+ PY + PL V + TL C G P ++W GV+V D + I G+ L
Sbjct: 4037 QPPYFL-LPLSDKVVIDEKCTLKCVVMGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIALL 4095
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESKQSAQGDT---- 124
R + + D V CEA N G + V E L+ S + DT
Sbjct: 4096 RMKN--IKKDKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTTT 4153
Query: 125 --VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG-RYQCI 181
L+C+ G+P P+V NG T +S++ D G ++IQ T+ G +C
Sbjct: 4154 DHATLKCIVV-GTPLPDVSCSFNGVT----DNSKIRSED-GIVLIQVNDVTEEGIVVECT 4207
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS-----SVTFQCRVGGDPLPDVLWR 236
N G+ S I + P V Q GS ++ + V P P + W+
Sbjct: 4208 ISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEPTLFWK 4267
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEG--EYSCEAENSVG 279
+ + +DG + + V +G E++C A+N G
Sbjct: 4268 HNGKSIEEGGDYYLIFEDG-IGILKVFNIQDGSHEFTCIAKNEYG 4311
Score = 49.6 bits (113), Expect = 1e-05
Identities = 85/383 (22%), Positives = 144/383 (37%), Gaps = 36/383 (9%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
L P S + + L+C+ G P V W +G + D + +H DG L+
Sbjct: 4042 LLPLSDKVVIDEKCTLKCVV-MGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIALLRMKNI 4100
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHI---------KPYLITGPEDVVAQTGSSVTFQ 222
+ D QC A N G ++ K + KP + +D T + T +
Sbjct: 4101 KKDKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTTTDHA-TLK 4159
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG-EYSCEAENSVGAV 281
C V G PLPDV + N + +DG + + + +EG C N G+
Sbjct: 4160 CIVVGTPLPDVSCSFNGVTDNSKIRS----EDGIVLIQVNDVTEEGIVVECTISNETGSS 4215
Query: 282 SASGYLTVYDPPSINLS-PNSVNVESGNV--ARFTCTATG---RPEPTMFWSVEGNRTII 335
+++ + + N P V ++G+V R G PEPT+FW G ++I
Sbjct: 4216 TSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEPTLFWKHNG-KSIE 4274
Query: 336 FPGMSRDKYHATAVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
G D Y +F DG+ +L + + D + C A N G + V + + +
Sbjct: 4275 EGG---DYY---LIFEDGIGILKVFNI--QDGSHEFTCIAKNEYGQTTVEIPVEIGLKTE 4326
Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
++ N + + A W+ +G+ L + +T D +
Sbjct: 4327 NKLTLVKT--LNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILEDDSSHKITVDKCIST 4384
Query: 455 KDLDKSDSGT--YTCVASSRHGK 475
L ++GT TC S+ K
Sbjct: 4385 LQLKLEETGTRIITCEVSNSSSK 4407
Score = 46.0 bits (104), Expect = 2e-04
Identities = 62/281 (22%), Positives = 104/281 (37%), Gaps = 14/281 (4%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
T + P P D+T ++ + G P+P I W+K + S + I G
Sbjct: 15594 TESKKPAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIAGA 15653
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--QGDT 124
L R D G Y N+ G+ + L + L E R++ + +G+T
Sbjct: 15654 TSLTIGEMR-EDDEGEYKIVVKNTAGSV-EHSCKLTMDQLPEINRVDRYASTLVFDKGET 15711
Query: 125 VVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIA 182
V L L G P+P V W NG+ + ++ V L I D G +
Sbjct: 15712 VKLR-LSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEFALKI 15770
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRRS 238
+N G + AI +++ +P G V Q SV + GG P+ +
Sbjct: 15771 KNRCGEDKYAIG-IQVTDRP-AAPGKPAVEDQNVDSVRLRWAAPTNDGGSPVRNYTVEMC 15828
Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
G + +V + L N++ + + A+N+ G
Sbjct: 15829 TEKGK-TWTKAEVTKQAFITLFNLVPGESYRFRVRADNTFG 15868
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
Query: 209 EDVVAQTGSSV-TFQCRVGGDPLPDVLWRRSAGGGNMPLGRV-KVLDDG--SLRLDNVIL 264
ED+VA G + T C V G P P V W + +P + ++G L + N++
Sbjct: 16260 EDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVE 16319
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV 289
+D G+Y+C A N +G++ L+V
Sbjct: 16320 SDAGKYTCRATNDLGSIMTHAKLSV 16344
Score = 45.6 bits (103), Expect = 2e-04
Identities = 65/264 (24%), Positives = 104/264 (39%), Gaps = 42/264 (15%)
Query: 397 PPIITNGPSNQTLPIKSMA----VFPCTAICTPEPIIAWYFEGEALIQNHRRNV-TNDGT 451
PP+I N T PI A + + P P + GE + + + + N +
Sbjct: 8855 PPVILN---KLTKPITHQAGKSFTYKFNFMGAPAPRLRVLSNGEPVSFDVKYEIYDNIAS 8911
Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKP 510
L + + K D G YT V +++GK + +VD+P+ P R A + +L
Sbjct: 8912 LYIPKMSKRDGGEYTVVLENKYGKDESDLHITMVDTPLKP-----RKAQLVAL------- 8959
Query: 511 ITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQT 570
TDTS T W + G S IL Y V S E SR W I V +
Sbjct: 8960 -----TDTSATFKWLPPHT-GESDILHYIVMRRSTE----------SRRWRNIGH-VQEK 9002
Query: 571 HYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS----NSTEY 626
+ L+P Y F + N G PS + + T+ D ++ G + +
Sbjct: 9003 TFTAIELVPNEFYAFRIVAVNGFGEGAPSEIIEVNTLDYDQEESFDFAGEEELKLDDVQV 9062
Query: 627 RNNILTDHIVELIEATPIDSKTIK 650
N ++T+ +E E T + + +K
Sbjct: 9063 NNEVVTEITIEESEVTIEEHRKLK 9086
Score = 45.2 bits (102), Expect = 3e-04
Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Query: 1 MSDDYVTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59
+SD +TS P +++ P VT + T+ C+ G P PA W K GVL+ ++
Sbjct: 3886 ISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQKYQ- 3944
Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
+ G L+ + D VY C N G S + T+ V
Sbjct: 3945 VTTEDGTSILKIESASL-DDKAVYTCTIANEAG-CESTSCTIDV 3986
Score = 44.8 bits (101), Expect = 4e-04
Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-DDGS--LRLDNVILADEGEYSC 272
G V +C + G P P++ W G +P ++ +DG LR+++ ++ DEGEY C
Sbjct: 1693 GEPVQLKCLIAGMPQPEIEWTVD-GDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYCC 1751
Query: 273 EAENSVGAVSASGYL 287
A N G + YL
Sbjct: 1752 TASNVAGTTFSKCYL 1766
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP + + ++ +P L C G P P I W G +V + SI+ G+ L
Sbjct: 1677 QAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCIL 1736
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR 97
R + D G Y C A+N GT S+
Sbjct: 1737 R-IESTLIEDEGEYCCTASNVAGTTFSK 1763
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 7/88 (7%)
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G + C G P+P + W+V+G+ P + D+Y + DGV +L I T D
Sbjct: 1693 GEPVQLKCLIAGMPQPEIEWTVDGD-----PIVPNDEY-SIVYEDGVCILRIESTLIED- 1745
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
C+A N AG++F + L ++ DD
Sbjct: 1746 EGEYCCTASNVAGTTFSKCYLKLSEADD 1773
Score = 41.9 bits (94), Expect = 0.003
Identities = 47/233 (20%), Positives = 83/233 (35%), Gaps = 18/233 (7%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
D + +VI+A+ G E +++ +Y P S + +
Sbjct: 3750 DSEQIVSDVIVAEVGYDEDECSTIADTITSLSSSPLYTAPVFTERLPSSACFANSKLTLE 3809
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
+G P+PT+ W ++ + + S + + +GV+ + + D+N + + C
Sbjct: 3810 VMFSGVPQPTISWLIDDHELV-----SDGERISIKCENGVSAIRFFNVDRN-AGGFLKCR 3863
Query: 374 AVNYAGSS------FVRGKLTVTSDDD----RPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
A N AG +++V SD P + P T + C
Sbjct: 3864 ATNCAGQVETSCEIVAADEISVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSG 3923
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK--DLDKSDSGTYTCVASSRHG 474
P P W +G L + T DGT +LK D YTC ++ G
Sbjct: 3924 QPLPAAMWEKDGVLLDLQKYQVTTEDGTSILKIESASLDDKAVYTCTIANEAG 3976
Score = 41.5 bits (93), Expect = 0.004
Identities = 115/501 (22%), Positives = 183/501 (36%), Gaps = 55/501 (10%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGR 177
+GD V +E + + V WK NG+ D +SR H + L+I + TD+G
Sbjct: 13887 RGDNVEIEA--ELLAEDDTVTWKVNGKDA--DLNSRCHEMSHTFFRTLIIDEVEPTDSGM 13942
Query: 178 YQCIARNAAGTRESAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGD-PLPDVL 234
+ A GT ES LK+ P ++ P + G VT + + V+
Sbjct: 13943 -EITA--TCGT-ESHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVV 13998
Query: 235 WRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
W + G + + + +D SL L D G+Y + V S +L++
Sbjct: 13999 WLKD--GKPLEINKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDG----VDCSTHLSIQ 14052
Query: 291 DPPSI-NLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P + N+S + V+ + PE + +V+G + + F G SR
Sbjct: 14053 GKPVLKNVSETKPVITVDKDDQFSLLVAYDSNPEASFSMTVDG-KDLEFDGRSR----ID 14107
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
V DG+ LT K D+ V N G + + V P + +
Sbjct: 14108 VVDDGLK-LTKRGVSKTDAGEYEV-KLKNEFGEVAQKFDVKVNDTPSAPGDVSVVKAESD 14165
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
L I+ A +I G + V+ DL+
Sbjct: 14166 CLHIEWTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRI 14225
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
A ++ G +G + P+ F V ++ PPT NVT TS +LSW +
Sbjct: 14226 AAVNKFG----TGEFIETKPVQTGSPF----QVPTVEFPPT---IDNVTSTSCSLSWPKP 14274
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
+ G S + GY +V+ RE G N V + V++L G Y F +
Sbjct: 14275 IEDGGSPVYGY--DVYKREN-EGEWQKMNGE------ELVFTESFNVRALSSGKEYEFKI 14325
Query: 588 RTENSHGL-SGPSPVSDSVTV 607
N GL S + VS +TV
Sbjct: 14326 EACNEAGLRSNSNVVSKKLTV 14346
Score = 39.9 bits (89), Expect = 0.011
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAGG 65
AP I+E + Q +L C+ +PS A+ W K V V D ++L G
Sbjct: 820 APKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGV 879
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
L DAG+Y C ATN +GTA +
Sbjct: 880 CELLNPEC--FAEDAGLYKCTATNPHGTAET 908
Score = 38.7 bits (86), Expect = 0.025
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
G+ V L+CL G P+P + W +G ++ + + + DG ++ I+ D G Y C
Sbjct: 1693 GEPVQLKCLIA-GMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYCC 1751
Query: 181 IARNAAGT 188
A N AGT
Sbjct: 1752 TASNVAGT 1759
Score = 38.7 bits (86), Expect = 0.025
Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 160 VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL-KIHIKPYLITGPEDVVAQTGSS 218
+DGG LV + + D G +C S I +IH + DV + G +
Sbjct: 12243 LDGGKLVFE--AKNDYGVDKCTILLDVRDSGSFIEDYSEIHRSAEIQNSVGDVQVKEGET 12300
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV-LD---DGSL--RLDNVILADEGEYSC 272
RV G PLP+++W ++ +M + K LD DG R+ N D+ +YS
Sbjct: 12301 AKLTGRVDGFPLPELIWIKNGKEIDMMVPSTKYQLDYHSDGEFEARIANCTFEDDDDYSL 12360
Query: 273 EAENSVGAVSAS 284
EN G S +
Sbjct: 12361 LVENLAGVDSCN 12372
Score = 37.9 bits (84), Expect = 0.043
Identities = 44/186 (23%), Positives = 80/186 (43%), Gaps = 14/186 (7%)
Query: 114 PESKQSAQGDT-VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR- 171
P+S Q ++ V+++C P + W NG LL D M V G V++ +
Sbjct: 8771 PKSHAVGQMNSEVIIKC--KTSQPISDAKWFCNGMVLLPDEQVNM-TVTGCEAVLRLVKF 8827
Query: 172 -QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-PEDVVAQTGSSVTFQCRVGGDP 229
+ G Y + + G++ A L + P ++ + + Q G S T++ G P
Sbjct: 8828 LPQNKGNYHVLIDGSIGSQP---AILSGPVPPVILNKLTKPITHQAGKSFTYKFNFMGAP 8884
Query: 230 LPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P + R + G + + ++ D+ SL + + D GEY+ EN G + ++
Sbjct: 8885 APRL--RVLSNGEPVSFDVKYEIYDNIASLYIPKMSKRDGGEYTVVLENKYGKDESDLHI 8942
Query: 288 TVYDPP 293
T+ D P
Sbjct: 8943 TMVDTP 8948
Score = 37.9 bits (84), Expect = 0.043
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 14/106 (13%)
Query: 508 TKPITHNVTDT---SVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564
+KP + VT T +VTL+WS ++ S++ Y VE R+T+ G A
Sbjct: 10460 SKPTSLQVTSTERETVTLTWSLPTELNGSNVNEYLVE---RKTVDGGRWRH--------A 10508
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
V + VV L G Y+F V N G S PS ++ T ++
Sbjct: 10509 CTVTDSRAVVDGLFSGTEYVFRVVAVNGAGQSAPSDTIEATTQAEE 10554
Score = 37.9 bits (84), Expect = 0.043
Identities = 44/189 (23%), Positives = 69/189 (36%), Gaps = 21/189 (11%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV--- 76
D+ + P TL+C GSP P + W + + H+ L + + G+V
Sbjct: 17669 DMGIVNGHPTTLSCNVTGSPEPTLEW----IYIDDSGHKINLTSSTTDWTECRFGKVAEL 17724
Query: 77 ------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE-- 128
G Y C ATNS G A ++ L V L +E P + Q L+
Sbjct: 17725 KSERVLREQRGTYQCIATNSSGQATTQ-CYLLVGELSDEPAGPPRFVKCLQDTWTPLKES 17783
Query: 129 ---CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIAR 183
+ G P P++ W N + + D ++ L I++ G Y A
Sbjct: 17784 IEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEAS 17843
Query: 184 NAAGTRESA 192
N G +A
Sbjct: 17844 NIHGVLRTA 17852
Score = 37.1 bits (82), Expect = 0.076
Identities = 28/111 (25%), Positives = 52/111 (46%), Gaps = 11/111 (9%)
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
R A +R + K +KP P V+ + S+ + + G+P+P V W + G
Sbjct: 17980 RAAINSRNKRVCRPKFMVKPK----PRKVLEEY-KSLRLKTAISGNPMPQVHWDKE--GI 18032
Query: 243 NMPLG-RVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+ G + + +DG L + +V D+G Y+C A N+ G ++ + + V
Sbjct: 18033 ILETGNKYSIYNDGDFYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDV 18083
Score = 35.5 bits (78), Expect = 0.23
Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 14/105 (13%)
Query: 509 KPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVH 568
KP + T TS+ L W+ +N + Y V++ + R W V+A+ +
Sbjct: 15506 KPEYVSSTATSIALKWTSDN-----DEVTYTVQM---------KEANSKRPWAVVAKEIS 15551
Query: 569 QTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ + L G +Y+F V +N G + S S+S+ D + S
Sbjct: 15552 ECSATIAQLKEGTSYLFRVIAQNKTGQTVTSEQSESIECKDTTES 15596
Score = 34.7 bits (76), Expect = 0.40
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 7/87 (8%)
Query: 112 LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKK---NGQTLLFDGDSRMHLVDGG--NL 165
+EP S G + L C +P V W K N + + + D ++DGG L
Sbjct: 824 VEPLHSASFLDGQAMSLRC-KITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGVCEL 882
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESA 192
+ + DAG Y+C A N GT E+A
Sbjct: 883 LNPECFAEDAGLYKCTATNPHGTAETA 909
Score = 34.3 bits (75), Expect = 0.53
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTND-GT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P + WYF E L + ++ + GT ++LK++ K G Y A + HG+ +
Sbjct: 1162 PTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKRQGGNYFLRAHNCHGESILPMK 1221
Query: 482 LLVDSPINPNIH 493
L VD PI H
Sbjct: 1222 LTVD-PIEAVTH 1232
Score = 34.3 bits (75), Expect = 0.53
Identities = 48/218 (22%), Positives = 86/218 (39%), Gaps = 12/218 (5%)
Query: 7 TSGEAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
T G IIE P V + + + C+ S A +W+ G++++ D ++ G
Sbjct: 8760 TIGTGQSIIEHPKSHAVGQMNSEVIIKCKTSQPISDA-KWFCNGMVLLPDEQVNMTVTGC 8818
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + + G Y S G+ + + V+ + +P + Q+ + T
Sbjct: 8819 EAVLRLVK-FLPQNKGNYHVLIDGSIGSQPAILSGPVPPVILNKL-TKPITHQAGKSFTY 8876
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184
+ G+P P + NG+ + F D + + D +L I + D G Y + N
Sbjct: 8877 KFNFM---GAPAPRLRVLSNGEPVSF--DVKYEIYDNIASLYIPKMSKRDGGEYTVVLEN 8931
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
G ES + + L +VA T +S TF+
Sbjct: 8932 KYGKDESDLHITMVDTP--LKPRKAQLVALTDTSATFK 8967
Score = 34.3 bits (75), Expect = 0.53
Identities = 15/43 (34%), Positives = 19/43 (44%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG 49
T G P E P+ V A L G+P+PA RW+ G
Sbjct: 18409 TVGAKPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNG 18451
Score = 33.9 bits (74), Expect = 0.71
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 135 SPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
S P ++ W N +++L D D R + G N+ + + G Y+C+ RN AG S
Sbjct: 115 SDPPAIFEWFYNEKSVLQDRD-RFQVGHGINISRLKVSRPEQGVYKCVTRNPAGVSTSYG 173
Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTF 221
+ +L + ED+ Q SVT+
Sbjct: 174 YITVNADREHLSSSKEDMRLQRQHSVTY 201
Score = 33.9 bits (74), Expect = 0.71
Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 504 PGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQVE 541
PG PT PI + VT++S SW G I GY VE
Sbjct: 15380 PGIPTGPIVFDDVTESSAEFSWKAPENNGGCEITGYNVE 15418
Score = 33.5 bits (73), Expect = 0.93
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRR--NVTNDGT--LVLKDLDKSDSGTYTCVA 469
+A C P P + WY + + L + + N+G L +K++ +SD+G YTC A
Sbjct: 16270 IATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRA 16329
Query: 470 SSRHGKYVWSGALLV 484
++ G + L V
Sbjct: 16330 TNDLGSIMTHAKLSV 16344
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Query: 429 IAWYFEGEALIQNHRRNVTN--DGT--LVLKDLDKSDSGTYTCVASSRHG 474
++W +G + +N + V DG L ++ DSG YTC A S HG
Sbjct: 976 VSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDSGVYTCTAESEHG 1025
Score = 33.1 bits (72), Expect = 1.2
Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 2/69 (2%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQ 179
GD + G P P V W K+ + L + G L +++ ++DAG+Y
Sbjct: 16267 GDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYT 16326
Query: 180 CIARNAAGT 188
C A N G+
Sbjct: 16327 CRATNDLGS 16335
Score = 32.7 bits (71), Expect = 1.6
Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDK--SDSGTYTCVASSRHG 474
C P+P I W +G+ ++ N ++ DG +L+ D G Y C AS+ G
Sbjct: 1700 CLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYCCTASNVAG 1758
Score = 30.3 bits (65), Expect = 8.7
Identities = 28/125 (22%), Positives = 47/125 (37%), Gaps = 7/125 (5%)
Query: 243 NMPLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
N+ + ++ LD G L + N D+ + +S + Y ++ I S
Sbjct: 12234 NVTINDIRKLDGGKLVFEAKNDYGVDKCTILLDVRDSGSFIE--DYSEIHRSAEIQNSVG 12291
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNR-TIIFPGMSRD-KYHATAVFDG-VTVLT 357
V V+ G A+ T G P P + W G ++ P YH+ F+ + T
Sbjct: 12292 DVQVKEGETAKLTGRVDGFPLPELIWIKNGKEIDMMVPSTKYQLDYHSDGEFEARIANCT 12351
Query: 358 INDTD 362
D D
Sbjct: 12352 FEDDD 12356
>AY130758-1|AAN61517.1| 18534|Caenorhabditis elegans 2MDa_1 protein
protein.
Length = 18534
Score = 106 bits (255), Expect = 8e-23
Identities = 134/531 (25%), Positives = 210/531 (39%), Gaps = 59/531 (11%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKG-GVLVVSDTHRSILPAGGLFFL 69
AP +Q DV + L +P+P I W++ + S HR G +
Sbjct: 16496 APSFGKQLSDVKCSESDILKLEVNIQANPAPEINWFRNESEIEHSQHHRLQFDDGSGNYS 16555
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-----------FRLE-PESK 117
D+G Y C A N G A + +L + FR++ P +
Sbjct: 16556 LTIIDAYAEDSGEYKCVAKNKIGKAHTVCCVRIEELLSKRSKKIDGSKAPRFRMQLPTPR 16615
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGR 177
+ QG + L C G+P PN+ W K+ + + H L I AR D GR
Sbjct: 16616 EVPQGADLTLVC-SVSGTPHPNIKWTKDDKPIDMSNKQVRHENGVCTLHIIGARDDDQGR 16674
Query: 178 YQCIARNAAGTRES------AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
Y C A N G +S A K H++P + + G+ + +C V G P+P
Sbjct: 16675 YVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIP 16734
Query: 232 DVLWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLT 288
+ W + + ++ D G RL+ NV++ D+GEY+CEA NS+G +
Sbjct: 16735 TITWYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGEYTCEAVNSLGKDFTHCTVK 16794
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATG---RP----EPTMFWSV-EGNRTII----- 335
V D V S + +R G RP P +V EGNR ++
Sbjct: 16795 VVDMGLSKTRLTPVRSRSRSRSRSPSVVGGEIQRPPVVTRPLADATVTEGNRELLEVEVD 16854
Query: 336 -FPGMSRDKYH----------ATAVFDG-VTVLTINDTDKNDSRNTIVCSAVNYAGSSFV 383
FP + + YH FDG V L I + + + VC N G+
Sbjct: 16855 GFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKIYEAHE-EHNGQYVCKVSNKLGAVET 16913
Query: 384 RGKLTVTSDD--DRPPPIITNGPSNQTLPIKS---MAVFPCTAICTPEPIIAWYFEGEAL 438
R + V + D + + T Q + +K+ A F C + P + W G+AL
Sbjct: 16914 RAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKAL 16973
Query: 439 IQ---NHRRNVTND--GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
Q N++ + +D TLV++++ GTYT VA+++ G S L +
Sbjct: 16974 QQTKSNYKTRLFDDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTI 17024
Score = 103 bits (246), Expect = 1e-21
Identities = 124/505 (24%), Positives = 180/505 (35%), Gaps = 52/505 (10%)
Query: 27 QPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCE 86
Q L CR + W+K + S + H D G Y C
Sbjct: 17373 QQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDKKSNHKLVCHAVQSQDTGKYRCV 17432
Query: 87 ATNSYGTARSR-NATLH--VAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
TN YG A S N + + F + G + LEC GSP P V W
Sbjct: 17433 VTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLEC-KVEGSPAPEVSWT 17491
Query: 144 KNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAG--TRESAIATLKI- 198
K+G+ + R + GN L I A D G Y C A + AG + S + K
Sbjct: 17492 KDGERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSSMVMIAKTT 17551
Query: 199 ---------------HIKPYLITGPEDVVAQTGSS-VTFQCRVGGDPLPDVLWRRSAGGG 242
H KP P ++ S T + G+P P V W + G
Sbjct: 17552 GTDSHLVIAQTADEKHEKPRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKD-GRE 17610
Query: 243 NMPLGRVK---VLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291
+ R+ V DG L + V+ G +SC+AEN G V A + V
Sbjct: 17611 ILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPANQ 17670
Query: 292 ----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV--EGNRTIIFPGMSRDKYH 345
P + + + +G+ +C TG PEPT+ W + I + D
Sbjct: 17671 LANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTD--W 17728
Query: 346 ATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV--TSDDDRPPPIITNG 403
F V L ++ + R T C A N +G + + L V SD+ PP
Sbjct: 17729 TECRFGKVAELK-SERVLREQRGTYQCIATNSSGQATTQCYLLVGELSDEPAGPPRFVKC 17787
Query: 404 PSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDGTLVL--KDLDK 459
+ P+K F P P + WY + + + +T +D T VL K++
Sbjct: 17788 LQDTWTPLKESIEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIKNVSL 17847
Query: 460 SDSGTYTCVASSRHGKYVWSGALLV 484
+ G Y AS+ HG +G L V
Sbjct: 17848 ASLGMYFVEASNIHGVLRTAGRLNV 17872
Score = 89.4 bits (212), Expect = 1e-17
Identities = 130/511 (25%), Positives = 194/511 (37%), Gaps = 74/511 (14%)
Query: 29 ATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEA 87
ATL+C G PSP ++WYK L V GL L V SDAG Y C A
Sbjct: 16286 ATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAEL-TVKNIVESDAGKYTCRA 16344
Query: 88 TNSYGTARSRNATLHVAV---LREEFRLEP----ESKQSAQGDTVVLE---CLPPR---- 133
TN G+ + +A L V +++ + P + K VV+E +PP
Sbjct: 16345 TNDLGSIMT-HAKLSVKADEKKKKKSKTSPAVIEKKKDRKTSKVVVIEEMIDMPPNFHHL 16403
Query: 134 --------GSP-----------EPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQ 172
G P EP V W NG+ + + + + D G L I
Sbjct: 16404 LQDDEAKIGEPKILVVTNTTLPEPTVDWYHNGEHISINDSNYLRKHDKGRYELHILSVDS 16463
Query: 173 TDAGRYQCIARNAAGTRES-AIATLKIHIKPYLIT-GPE--DVVAQTGSSVTFQCRVGGD 228
TD G+++ + +NA G ES A T+ I Y + G + DV + + + +
Sbjct: 16464 TDEGKWKAVGKNAFGECESEAKLTVVIPDGQYAPSFGKQLSDVKCSESDILKLEVNIQAN 16523
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSAS 284
P P++ W R+ DDG SL + + D GEY C A+N +G
Sbjct: 16524 PAPEINWFRNESEIEHSQHHRLQFDDGSGNYSLTIIDAYAEDSGEYKCVAKNKIGKAHTV 16583
Query: 285 GYLTVYD-------------PPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
+ + + P + P V G C+ +G P P + W+ +
Sbjct: 16584 CCVRIEELLSKRSKKIDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWT-KD 16642
Query: 331 NRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG--SSFVRGKLT 388
++ I MS + +GV L I ++D + VC A N G SF ++
Sbjct: 16643 DKPI---DMSNKQVRHE---NGVCTLHIIGA-RDDDQGRYVCEAENIHGVAQSFSVVEIK 16695
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
D D P N + + V C P P I WY +G LI +R
Sbjct: 16696 EAVDKDHVRPKFLEPLVNCSTCEGNEMVLECCVTGKPIPTITWYKDGLKLIIENRMLQYT 16755
Query: 449 D----GTLVLKDLDKSDSGTYTCVASSRHGK 475
D L + ++ +D G YTC A + GK
Sbjct: 16756 DRKGVSRLNIMNVVMNDDGEYTCEAVNSLGK 16786
Score = 88.2 bits (209), Expect = 3e-17
Identities = 127/555 (22%), Positives = 211/555 (38%), Gaps = 92/555 (16%)
Query: 9 GEAPYIIEQPLDVTVA-RHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G+AP P +A R + G+P+P+++WYK + +V D +
Sbjct: 17246 GQAPQFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYKENLQIVPDEKIDVATTSTSS 17305
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE--PE---------- 115
L + + G + C N G A +A+ V + + L+ P+
Sbjct: 17306 ILNL---KSQEENGTFNCLIENELGQA---SASCQVTIFNKPASLQSTPDHSLERNLVPT 17359
Query: 116 -----SKQSAQ-GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVI 167
+ +SAQ G ++L C S E V W K+ + + G + N LV
Sbjct: 17360 LQKALNNESAQAGQQIMLTCRISSRS-ESTVAWFKDDERIESAGRYELSSDKKSNHKLVC 17418
Query: 168 QDARQTDAGRYQCIARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQTGSSVTFQC 223
+ D G+Y+C+ N G ES A+ + I P D A G ++T +C
Sbjct: 17419 HAVQSQDTGKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLEC 17478
Query: 224 RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS----LRLDNVILADEGEYSCEAENSVG 279
+V G P P+V W + G R++ D + L + D G Y C A + G
Sbjct: 17479 KVEGSPAPEVSWTKD-GERISTTRRIRQTQDENGNCKLSISKAESDDMGVYVCSATSVAG 17537
Query: 280 AVSASGYLTV-------------------YDPPSINLSPNSVNVESGNVARFT--CTATG 318
S S + + ++ P +P S+ +E +FT A G
Sbjct: 17538 VDSTSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPSL-IEVNESGQFTLIAKAVG 17596
Query: 319 RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYA 378
P+PT+ W +G + + YH DG + L I + + + C A N
Sbjct: 17597 EPKPTVTWLKDGREIL----RTNRIYHHFVTGDGESHL-IAECVVSKTSGIFSCKAENPN 17651
Query: 379 GSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV---FPCTAIC----TPEPIIAW 431
G+ V + V +P + N T+P+ M + P T C +PEP + W
Sbjct: 17652 GT--VIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPTTLSCNVTGSPEPTLEW 17709
Query: 432 YFEGEALIQNHRRNVTNDGT------------LVLKDLDKSDSGTYTCVASSRHGKYVWS 479
+ ++ H+ N+T+ T L + + + GTY C+A++ G+
Sbjct: 17710 IYIDDS---GHKINLTSSTTDWTECRFGKVAELKSERVLREQRGTYQCIATNSSGQATTQ 17766
Query: 480 GALLV----DSPINP 490
LLV D P P
Sbjct: 17767 CYLLVGELSDEPAGP 17781
Score = 84.6 bits (200), Expect = 4e-16
Identities = 115/510 (22%), Positives = 200/510 (39%), Gaps = 73/510 (14%)
Query: 39 PSPAIRWYKGGVLV-VSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSR 97
P P + WY G + ++D++ G + L +D G + N++G S
Sbjct: 16425 PEPTVDWYHNGEHISINDSNYLRKHDKGRYELHILSVD-STDEGKWKAVGKNAFGECESE 16483
Query: 98 NATLHVAV----LREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDG 153
A L V + F + + ++ D + LE + + +P P + W +N +
Sbjct: 16484 -AKLTVVIPDGQYAPSFGKQLSDVKCSESDILKLE-VNIQANPAPEINWFRNESEIEHSQ 16541
Query: 154 DSRMHLVDG-GN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH----IKPYLIT 206
R+ DG GN L I DA D+G Y+C+A+N G + + ++I + I
Sbjct: 16542 HHRLQFDDGSGNYSLTIIDAYAEDSGEYKCVAKNKIG-KAHTVCCVRIEELLSKRSKKID 16600
Query: 207 G----------PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG- 255
G P G+ +T C V G P P++ W + +M +V+ ++G
Sbjct: 16601 GSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDDKPIDMSNKQVR-HENGV 16659
Query: 256 -SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--------PPSINLSPNSVNVES 306
+L + D+G Y CEAEN G + + + + P + N E
Sbjct: 16660 CTLHIIGARDDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCSTCE- 16718
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
GN C TG+P PT+ W +G + II ++ GV+ L I + ND
Sbjct: 16719 GNEMVLECCVTGKPIPTITWYKDGLKLII-----ENRMLQYTDRKGVSRLNIMNVVMNDD 16773
Query: 367 RNTIVCSAVNYAGSSFV------------RGKLT--------------VTSDDDRPPPII 400
C AVN G F + +LT V + + PP++
Sbjct: 16774 -GEYTCEAVNSLGKDFTHCTVKVVDMGLSKTRLTPVRSRSRSRSRSPSVVGGEIQRPPVV 16832
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDL 457
T ++ T+ + + P P I WY +G+ + ++ DG L + +
Sbjct: 16833 TRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAFLKIYEA 16892
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ +G Y C S++ G ++V++P
Sbjct: 16893 HEEHNGQYVCKVSNKLGAVETRAIVVVEAP 16922
Score = 81.0 bits (191), Expect = 5e-15
Identities = 80/335 (23%), Positives = 142/335 (42%), Gaps = 19/335 (5%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAG 64
V + +AP +++ V + + L C A G P+P WYK G ++ +D + I+ G
Sbjct: 14445 VLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKDGKEIIPTDENTEIVNEG 14504
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE-PESKQSAQGD 123
+ L H D G+Y N +GTA S A + ++ +R F E + +G
Sbjct: 14505 SMSAL-IIHELAGEDVGLYKVLVENIHGTAES-EAEVGISDVRAHFNSSFSELTEIEEGH 14562
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIA 182
+ L C E V W K+G+ L+ + + + L I+ + D+G Y+C
Sbjct: 14563 DIELTC--EVSDEEAVVNWYKDGKKLVASDRVQFYAMARKRTLRIKGSTDADSGVYKCET 14620
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
+ E + + +P+++ GP+D +V G ++ C P+ V W ++
Sbjct: 14621 TDGRSRTEGEV--IVNEQEPHILVGPQDAIVKDFGETMVLFCET-SKPVRKVKWFKNGVE 14677
Query: 242 GNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
+ + + +DG +L + N D G Y+ A S SA L P++ +
Sbjct: 14678 IWPQMNKAIMENDGKRATLEIKNFDKHDIGAYT--ASVSEKETSAPAKLVFEVAPNLIIP 14735
Query: 299 P---NSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
+ V V +GN F +G P PT+ + G
Sbjct: 14736 TEIRDGVTVHAGNEFDFAVEFSGFPIPTIHLTNNG 14770
Score = 79.8 bits (188), Expect = 1e-14
Identities = 82/338 (24%), Positives = 132/338 (39%), Gaps = 27/338 (7%)
Query: 10 EAPYIIEQPL-DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
+ P ++ +PL D TV L G P+P I WY G LV G + F
Sbjct: 16827 QRPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHDGKLVAESRTLRTYFDGRVAF 16886
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSR--------NATLHVAVLREEFRLEPESKQSA 120
L+ + G Y C+ +N G +R +A HV + + +
Sbjct: 16887 LKIYEAHEEHN-GQYVCKVSNKLGAVETRAIVVVEAPDAAEHVTQMPTFVKKLQDVVLKT 16945
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDG--GNLVIQDARQTDAGR 177
G+T C +P V W NG+ L + + L D LVI++ G
Sbjct: 16946 AGETATFTC-QSYANPAAQVVWLHNGKALQQTKSNYKTRLFDDNTATLVIENVTDELCGT 17004
Query: 178 YQCIARNAAG-TRESAIATL------KIHIK-PYLITGPEDVV-AQTGSSVTFQCRVGGD 228
Y +A N G SA T+ KI PY I + + G++++ Q + G
Sbjct: 17005 YTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFIIELKPKINVVEGATLSIQADLNGS 17064
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P+P+V+W + + R+++ DG L + +V L DEG Y+ AEN G + +
Sbjct: 17065 PIPEVVWLKD-NSELVESDRIQMKCDGVNYQLLVRDVGLEDEGTYTITAENEKGKIRQNT 17123
Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
++V + VE + + G P P+
Sbjct: 17124 EVSVTKSKEVKEKKEKKKVEKKDEGKKKPGRPGLPRPS 17161
Score = 68.1 bits (159), Expect = 4e-11
Identities = 106/471 (22%), Positives = 178/471 (37%), Gaps = 66/471 (14%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F + P+SK A D + G+P P+V W K + L D ++ + I
Sbjct: 17250 QFTISPQSKIIANRDDEFEIAVEFSGTPTPSVKWYK--ENLQIVPDEKIDVATTSTSSIL 17307
Query: 169 DAR-QTDAGRYQCIARNAAGTRESAIA----------------TLKIHIKPYLITGPEDV 211
+ + Q + G + C+ N G ++ +L+ ++ P L +
Sbjct: 17308 NLKSQEENGTFNCLIENELGQASASCQVTIFNKPASLQSTPDHSLERNLVPTLQKALNNE 17367
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
AQ G + CR+ V W R G L K + L V D
Sbjct: 17368 SAQAGQQIMLTCRISSRSESTVAWFKDDERIESAGRYELSSDK-KSNHKLVCHAVQSQDT 17426
Query: 268 GEYSCEAENSVGAVSASGYLTVYD-----PPSINLSPNSVNVESGNVARFTCTATGRPEP 322
G+Y C N G + + V D PS + + + G+ C G P P
Sbjct: 17427 GKYRCVVTNKYGYAESECNVAVEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAP 17486
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG--- 379
+ W+ +G R + + T +G L+I+ + +D VCSA + AG
Sbjct: 17487 EVSWTKDGERI-----STTRRIRQTQDENGNCKLSISKAE-SDDMGVYVCSATSVAGVDS 17540
Query: 380 -SSFVR-GKLT---------VTSDDDRPPPIITNGPSNQTLPIKSMAVFP--CTAICTPE 426
SS V K T T+D+ P T P + + + F A+ P+
Sbjct: 17541 TSSMVMIAKTTGTDSHLVIAQTADEKHEKPRFTRAPPS-LIEVNESGQFTLIAKAVGEPK 17599
Query: 427 PIIAWYFEGEALIQNHR---RNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P + W +G +++ +R VT DG L+ + + SG ++C A + +G +
Sbjct: 17600 PTVTWLKDGREILRTNRIYHHFVTGDGESHLIAECVVSKTSGIFSCKAENPNGTVIAETQ 17659
Query: 482 LLVD--SPIN--PNI---HFFRAADVSSLPGPPTKPITHNVTDT-SVTLSW 524
++V P N N+ D+ + G PT ++ NVT + TL W
Sbjct: 17660 VIVQRMKPANQLANVAPKFTIPLTDMGIVNGHPT-TLSCNVTGSPEPTLEW 17709
Score = 68.1 bits (159), Expect = 4e-11
Identities = 100/393 (25%), Positives = 148/393 (37%), Gaps = 52/393 (13%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG----LFFLRATHGRVHSDAGVYWCE 86
+ C P +I W + V ++ R + G L F+ T G D G Y CE
Sbjct: 18141 VECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPG----DEGTYACE 18196
Query: 87 ATNSYGTARSRNATLHVAVLREE--------FRLEP--ESKQSAQGDTVVLECLPPRGSP 136
A N G+A + N L V+ + FR E ++ G V L + S
Sbjct: 18197 AVNELGSAVT-NMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASE 18255
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
+ W +N T++ D S + L I D D G Y A+N +G A
Sbjct: 18256 PLQIRWLRNKVTIV-DSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGI---ARC 18311
Query: 195 TLKIHIK----------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
T+++ ++ P + + G SV + +V G P P + W ++ N
Sbjct: 18312 TMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVELRAKVIGHPDPVISWTKAGQKLNN 18371
Query: 245 PLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDP-------PS 294
+ + ++G LR+ NV AD G+Y A N G +A LTV P
Sbjct: 18372 E-EKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQANAELELTVVQSTKTVGAKPK 18430
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
N SP SV N A + +G P P W GN I G+ D Y T+ D +
Sbjct: 18431 FNESPISVQTCEKNRAELRASFSGTPAPACRWFYNGNELI--DGL--DGYTITS-SDTNS 18485
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKL 387
L IN DK +C+ N G +
Sbjct: 18486 SLLINSVDKKHF-GEYLCTIRNQNGEELANAMI 18517
Score = 66.1 bits (154), Expect = 1e-10
Identities = 56/201 (27%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Query: 6 VTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
+ +AP + ++ P V + TL C G+P P I+W K + +++ +
Sbjct: 16599 IDGSKAPRFRMQLPTPREVPQGADLTLVCSVSGTPHPNIKWTKDD-KPIDMSNKQVRHEN 16657
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNAT-LHVAVLREEFR---LEP-ESKQS 119
G+ L R D G Y CEA N +G A+S + + AV ++ R LEP + +
Sbjct: 16658 GVCTLHIIGAR-DDDQGRYVCEAENIHGVAQSFSVVEIKEAVDKDHVRPKFLEPLVNCST 16716
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177
+G+ +VLEC G P P + W K+G L+ + + G L I + D G
Sbjct: 16717 CEGNEMVLECC-VTGKPIPTITWYKDGLKLIIENRMLQYTDRKGVSRLNIMNVVMNDDGE 16775
Query: 178 YQCIARNAAGTRESAIATLKI 198
Y C A N+ G ++ T+K+
Sbjct: 16776 YTCEAVNSLG-KDFTHCTVKV 16795
Score = 62.1 bits (144), Expect = 2e-09
Identities = 70/318 (22%), Positives = 126/318 (39%), Gaps = 33/318 (10%)
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAG 240
+R+ + +R ++ +I +P ++T P D G+ + V G P P + W
Sbjct: 16810 SRSRSRSRSPSVVGGEIQ-RPPVVTRPLADATVTEGNRELLEVEVDGFPTPTIEWYHD-- 16866
Query: 241 GGNMPLGR-VKVLDDGSLRLDNVILADE---GEYSCEAENSVGAVSASGYLTVYDPPS-- 294
G + R ++ DG + + A E G+Y C+ N +GAV + V P +
Sbjct: 16867 GKLVAESRTLRTYFDGRVAFLKIYEAHEEHNGQYVCKVSNKLGAVETRAIVVVEAPDAAE 16926
Query: 295 -INLSPNSVNV-------ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHA 346
+ P V +G A FTC + P + W G ++ Y
Sbjct: 16927 HVTQMPTFVKKLQDVVLKTAGETATFTCQSYANPAAQVVWLHNGKAL----QQTKSNYK- 16981
Query: 347 TAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR------PPPII 400
T +FD T + + ++ T A N G +LT++ + + P II
Sbjct: 16982 TRLFDDNTATLVIENVTDELCGTYTAVANNQFGDVHTSAQLTISGSEAKKIAASLPYFII 17041
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDL 457
P + ++++ +P P + W + L+++ R + DG L+++D+
Sbjct: 17042 ELKPKINVVEGATLSI-QADLNGSPIPEVVWLKDNSELVESDRIQMKCDGVNYQLLVRDV 17100
Query: 458 DKSDSGTYTCVASSRHGK 475
D GTYT A + GK
Sbjct: 17101 GLEDEGTYTITAENEKGK 17118
Score = 62.1 bits (144), Expect = 2e-09
Identities = 106/502 (21%), Positives = 180/502 (35%), Gaps = 60/502 (11%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
L G+P P + W K G+++ + SI G ++L H D G Y C A N+
Sbjct: 18028 LKTAISGNPMPQVHWDKEGIILETGNKYSIYNDGDFYYLEVHHVSTF-DKGFYNCTAANN 18086
Query: 91 YG--TARSRNATLH------VAVLREEFRLE----------PESKQSAQGDTVVLECLPP 132
G T S L V + + R E P Q+ +++ +EC
Sbjct: 18087 EGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPNFIEVLPGRSQANLNESLCVEC-SV 18145
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRE 190
P ++ W +N LL D DG +L D G Y C A N G+
Sbjct: 18146 SAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKFISVTPGDEGTYACEAVNELGSAV 18205
Query: 191 SAIATLKIHIKPYLITGPEDVV----------AQTGSSVTFQCRV--GGDPLPDVLWRRS 238
+ + + P G + GS V + +PL + W R+
Sbjct: 18206 TNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGSRVELAAELVQASEPL-QIRWLRN 18264
Query: 239 AGG--GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD----- 291
+ + + L + +V D GEY+ EA+N G + L V +
Sbjct: 18265 KVTIVDSPSFSYSRSENMVFLTIADVFPEDGGEYTVEAKNQSGIARCTMQLDVRNNERSV 18324
Query: 292 ----PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P + P + + + G G P+P + W+ G + + +KY
Sbjct: 18325 ADEAPRVFDFEPTTRS-DPGVSVELRAKVIGHPDPVISWTKAGQKL-----NNEEKYMMR 18378
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDR--PPPIITNGPS 405
D + N T + + + +A+N +G + +LTV P P
Sbjct: 18379 NEGDKFILRIANVTRADAGKYEL--TAINPSGQANAELELTVVQSTKTVGAKPKFNESPI 18436
Query: 406 NQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-HRRNVTNDGT---LVLKDLDKSD 461
+ K+ A + TP P W++ G LI +T+ T L++ +DK
Sbjct: 18437 SVQTCEKNRAELRASFSGTPAPACRWFYNGNELIDGLDGYTITSSDTNSSLLINSVDKKH 18496
Query: 462 SGTYTCVASSRHGKYVWSGALL 483
G Y C +++G+ + + +L
Sbjct: 18497 FGEYLCTIRNQNGEELANAMIL 18518
Score = 59.7 bits (138), Expect = 1e-08
Identities = 108/529 (20%), Positives = 185/529 (34%), Gaps = 59/529 (11%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
+IIE + V ++ GSP P + W K +V ++ R + G+ +
Sbjct: 17039 FIIELKPKINVVEGATLSIQADLNGSPIPEVVWLKDNSELV-ESDRIQMKCDGVNYQLLV 17097
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPP 132
D G Y A N G R +N + V +E + + E K+ + D + P
Sbjct: 17098 RDVGLEDEGTYTITAENEKGKIR-QNTEVSVTKSKE-VKEKKEKKKVEKKDEGKKKPGRP 17155
Query: 133 RGSPEPNVYWKKNGQTLLFDGDS---------------RMHLVDGGN-----LVIQDARQ 172
G P P+ K T+ FD S + V G+ L I+
Sbjct: 17156 -GLPRPSGASKTEQVTMAFDAPSEGPADSYEVERRCPDQREWVSCGSTKSLELEIKGLTP 17214
Query: 173 TDAGRYQCIARNAAGTRE-----SAIATLKIHIKPYLITGPED-VVAQTGSSVTFQCRVG 226
++ +N G E S + T + P P+ ++A
Sbjct: 17215 NTEYIFRVAGKNKQGLGEWSEMTSTLKTASVGQAPQFTISPQSKIIANRDDEFEIAVEFS 17274
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE-GEYSCEAENSVGAVSASG 285
G P P V W + +P ++ V + + N+ +E G ++C EN +G SAS
Sbjct: 17275 GTPTPSVKWYKE-NLQIVPDEKIDVATTSTSSILNLKSQEENGTFNCLIENELGQASASC 17333
Query: 286 YLTVYDPPSI-----------NLSP------NSVNVESGNVARFTCTATGRPEPTMFWSV 328
+T+++ P+ NL P N+ + ++G TC + R E T+ W
Sbjct: 17334 QVTIFNKPASLQSTPDHSLERNLVPTLQKALNNESAQAGQQIMLTCRISSRSESTVAWFK 17393
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLT 388
+ R S +Y ++ L + D+ C N G + +
Sbjct: 17394 DDERI-----ESAGRYELSSDKKSNHKLVCHAVQSQDT-GKYRCVVTNKYGYAESECNVA 17447
Query: 389 VTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN 448
V P + S+ T + C +P P ++W +GE + R T
Sbjct: 17448 VEDVTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQ 17507
Query: 449 DGT----LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
D L + + D G Y C A+S G S +++ + H
Sbjct: 17508 DENGNCKLSISKAESDDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSH 17556
Score = 58.8 bits (136), Expect = 2e-08
Identities = 75/322 (23%), Positives = 109/322 (33%), Gaps = 39/322 (12%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAG 64
VT AP D T TL C+ GSP+P + W K G + + R
Sbjct: 17451 VTKFIAPSFSATLSDSTAILGHNITLECKVEGSPAPEVSWTKDGERISTTRRIRQTQDEN 17510
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGT---------ARSRNATLHVAVL--------R 107
G L + D GVY C AT+ G A++ H+ + +
Sbjct: 17511 GNCKLSISKAE-SDDMGVYVCSATSVAGVDSTSSMVMIAKTTGTDSHLVIAQTADEKHEK 17569
Query: 108 EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GN 164
F P S G P+P V W K+G+ +L H V G +
Sbjct: 17570 PRFTRAPPSLIEVNESGQFTLIAKAVGEPKPTVTWLKDGREILRTNRIYHHFVTGDGESH 17629
Query: 165 LVIQDARQTDAGRYQCIARNAAGT--RESAIATLKI-------HIKPYLITGPEDVVAQT 215
L+ + +G + C A N GT E+ + ++ ++ P D+
Sbjct: 17630 LIAECVVSKTSGIFSCKAENPNGTVIAETQVIVQRMKPANQLANVAPKFTIPLTDMGIVN 17689
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--------DGSLRLDNVILADE 267
G T C V G P P + W G+ D L+ + V+
Sbjct: 17690 GHPTTLSCNVTGSPEPTLEWIYIDDSGHKINLTSSTTDWTECRFGKVAELKSERVLREQR 17749
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A NS G + YL V
Sbjct: 17750 GTYQCIATNSSGQATTQCYLLV 17771
Score = 58.8 bits (136), Expect = 2e-08
Identities = 91/415 (21%), Positives = 163/415 (39%), Gaps = 54/415 (13%)
Query: 105 VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
V R +F ++P+ ++ + + G+P P V+W K G ++ + ++ + + G+
Sbjct: 18005 VCRPKFMVKPKPRKVLEEYKSLRLKTAISGNPMPQVHWDKEG--IILETGNKYSIYNDGD 18062
Query: 165 ---LVIQDARQTDAGRYQCIARNAAG------------TRESAIATL-------KIHIKP 202
L + D G Y C A N G +E + A + +
Sbjct: 18063 FYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDVLPNKEDSAAQVAKRKSRKEAKAPN 18122
Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRL 259
++ P A S+ +C V P ++W R++ R + DG SL+
Sbjct: 18123 FIEVLPGRSQANLNESLCVECSVSAYPCASIIWTRNSVRLLPQADRYTMSYDGECASLKF 18182
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTV--YDPPSINLSP--------NSV-NVESGN 308
+V DEG Y+CEA N +G+ + L V DP + P SV V G+
Sbjct: 18183 ISVTPGDEGTYACEAVNELGSAVTNMNLQVSGVDPNAAEGIPPLFRFEKIKSVRKVVDGS 18242
Query: 309 VARFTCTATGRPEPTMFWSVEGNRTII-FPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
EP + TI+ P S + + + LTI D D
Sbjct: 18243 RVELAAELVQASEPLQIRWLRNKVTIVDSPSFSYSR------SENMVFLTIADVFPEDGG 18296
Query: 368 NTIVCSAVNYAGSSFVRGKLTVTSDD----DRPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
V A N +G + +L V +++ D P + P+ ++ P S+ + I
Sbjct: 18297 EYTV-EAKNQSGIARCTMQLDVRNNERSVADEAPRVFDFEPTTRSDPGVSVEL-RAKVIG 18354
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSRHGK 475
P+P+I+W G+ L + + N+G L + ++ ++D+G Y A + G+
Sbjct: 18355 HPDPVISWTKAGQKLNNEEKYMMRNEGDKFILRIANVTRADAGKYELTAINPSGQ 18409
Score = 56.4 bits (130), Expect = 1e-07
Identities = 82/365 (22%), Positives = 137/365 (37%), Gaps = 46/365 (12%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P+ +P + + T TG P P + W N+ IF G K G
Sbjct: 15599 PAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFK--NKKEIFSG----KRQWIENIAG 15652
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI- 411
T LTI + ++D + N AGS KLT+ D+ P I TL
Sbjct: 15653 ATSLTIGEMREDDEGEYKIV-VKNTAGSVEHSCKLTM----DQLPEINRVDRYASTLVFD 15707
Query: 412 KSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYT 466
K V + P+P + W +I+ R+ + L + +D D G +
Sbjct: 15708 KGETVKLRLSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEFA 15767
Query: 467 CVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
+R G+ ++ + V+ P P KP + SV L W+
Sbjct: 15768 LKIKNRCGEDKYAIGI----------------QVTDRPAAPGKPAVEDQNVDSVRLRWAA 15811
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
G S + Y VE+ + + + W A Q + +L+PG +Y F
Sbjct: 15812 PTNDGGSPVRNYTVEMCTEK----------GKTWTK-AEVTKQAFITLFNLVPGESYRFR 15860
Query: 587 VRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDS 646
VR +N+ G S PS S+ V V + S + E + + ++ + + + ++ P +
Sbjct: 15861 VRADNTFGQSEPSDESELVVVKNVSRVVEEPKKKEVKVKEQESVDYERVAK--DSEPSEY 15918
Query: 647 KTIKL 651
KTI +
Sbjct: 15919 KTIDI 15923
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/177 (25%), Positives = 80/177 (45%), Gaps = 21/177 (11%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNAAGTRES 191
G P+P + W + L+ DG+ + G I+ + + G +C A N AG E+
Sbjct: 3814 GVPQPTISWLIDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCRATNCAGQVET 3873
Query: 192 A---IATLKIHI----------KPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+ +A +I + +P+ + PE V +T +C+ G PLP +W +
Sbjct: 3874 SCEIVAADEISVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEK 3933
Query: 238 SAGGGNMPLGRVKV-LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
G + L + +V +DG+ L++++ L D+ Y+C N G S S + V D
Sbjct: 3934 D--GVLLDLQKYQVTTEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDVVD 3988
Score = 55.2 bits (127), Expect = 3e-07
Identities = 78/358 (21%), Positives = 144/358 (40%), Gaps = 36/358 (10%)
Query: 134 GSPEPNVYWKKNGQTLLFD---GDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G E V +K +G ++ G R +I R+ ++ ARN GT E
Sbjct: 14376 GEKEFVVQYKSDGSSIWASVDIGGPRSESAATSKCIIDGLREGIPYVFRVAARNQHGTGE 14435
Query: 191 SAIATLKIHI----KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+ T+ + + P ++ + V + +C G P P+ +W + G +P
Sbjct: 14436 FSEPTIPVVVLADDAPRVLKAIKPVKIPKKGELRLECHAAGHPAPEYIWYKD-GKEIIPT 14494
Query: 247 GR-VKVLDDGSLR---LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS-INLSPNS 301
+++++GS+ + + D G Y EN G + + + D + N S +
Sbjct: 14495 DENTEIVNEGSMSALIIHELAGEDVGLYKVLVENIHGTAESEAEVGISDVRAHFNSSFSE 14554
Query: 302 VN-VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIND 360
+ +E G+ TC + E + W +G + + R +++A A + + D
Sbjct: 14555 LTEIEEGHDIELTCEVSDE-EAVVNWYKDGKKLV---ASDRVQFYAMARKRTLRIKGSTD 14610
Query: 361 TDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI--KSMAVFP 418
D + C + G S G++ V + P I GP + + ++M +F
Sbjct: 14611 ADSGVYK----CETTD--GRSRTEGEVIVNEQE----PHILVGPQDAIVKDFGETMVLFC 14660
Query: 419 CTAICTPEPIIAWYFEG-EALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASSR 472
T+ P + W+ G E Q ++ + NDG TL +K+ DK D G YT S +
Sbjct: 14661 ETS--KPVRKVKWFKNGVEIWPQMNKAIMENDGKRATLEIKNFDKHDIGAYTASVSEK 14716
Score = 54.4 bits (125), Expect = 5e-07
Identities = 45/171 (26%), Positives = 70/171 (40%), Gaps = 12/171 (7%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW---RRSAGGGNMPLGRVKVLDDGSL 257
KP P D+ A G P P++ W ++ G + SL
Sbjct: 15598 KPAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIE-NIAGATSL 15656
Query: 258 RLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSIN---LSPNSVNVESGNVARFTC 314
+ + DEGEY +N+ G+V S LT+ P IN +++ + G +
Sbjct: 15657 TIGEMREDDEGEYKIVVKNTAGSVEHSCKLTMDQLPEINRVDRYASTLVFDKGETVKLRL 15716
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
+ +GRP+P + W ++ N +I SR V + TVLTIN D D
Sbjct: 15717 SFSGRPQPEVIW-IDNNGKVI--EESRKMKIEKTVLN--TVLTINSIDSQD 15762
Score = 53.6 bits (123), Expect = 8e-07
Identities = 78/323 (24%), Positives = 121/323 (37%), Gaps = 21/323 (6%)
Query: 86 EATNSYGTARSRNATLHVAVLREEF-RLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
E T + GT S L V L +F + P +G V + V W K
Sbjct: 13943 EITATCGT-ESHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVVWLK 14001
Query: 145 NGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY 203
+G+ L + D + V +L ++ A+ D+G+Y+ + L I KP
Sbjct: 14002 DGKPLEINKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDGV-----DCSTHLSIQGKPV 14056
Query: 204 LITGPEDV-VAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL---GRVKVLDDG-SLR 258
L E V F V D P+ + + G ++ R+ V+DDG L
Sbjct: 14057 LKNVSETKPVITVDKDDQFSLLVAYDSNPEASFSMTVDGKDLEFDGRSRIDVVDDGLKLT 14116
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATG 318
V D GEY + +N G V+ + V D PS +P V+V A C
Sbjct: 14117 KRGVSKTDAGEYEVKLKNEFGEVAQKFDVKVNDTPS---APGDVSVVK---AESDCLHIE 14170
Query: 319 RPEPTMFWSVEGNRTIIFPGMS-RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
PT E +I S R K+H A +G + D + ++ + +AVN
Sbjct: 14171 WTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRIAAVNK 14230
Query: 378 AGS-SFVRGKLTVTSDDDRPPPI 399
G+ F+ K T + P +
Sbjct: 14231 FGTGEFIETKPVQTGSPFQVPTV 14253
Score = 50.4 bits (115), Expect = 8e-06
Identities = 71/285 (24%), Positives = 111/285 (38%), Gaps = 25/285 (8%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+ PY + PL V + TL C G P ++W GV+V D + I G+ L
Sbjct: 4037 QPPYFL-LPLSDKVVIDEKCTLKCVVMGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIALL 4095
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESKQSAQGDT---- 124
R + + D V CEA N G + V E L+ S + DT
Sbjct: 4096 RMKN--IKKDKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTTT 4153
Query: 125 --VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG-RYQCI 181
L+C+ G+P P+V NG T +S++ D G ++IQ T+ G +C
Sbjct: 4154 DHATLKCIVV-GTPLPDVSCSFNGVT----DNSKIRSED-GIVLIQVNDVTEEGIVVECT 4207
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS-----SVTFQCRVGGDPLPDVLWR 236
N G+ S I + P V Q GS ++ + V P P + W+
Sbjct: 4208 ISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEPTLFWK 4267
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEG--EYSCEAENSVG 279
+ + +DG + + V +G E++C A+N G
Sbjct: 4268 HNGKSIEEGGDYYLIFEDG-IGILKVFNIQDGSHEFTCIAKNEYG 4311
Score = 49.6 bits (113), Expect = 1e-05
Identities = 85/383 (22%), Positives = 144/383 (37%), Gaps = 36/383 (9%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
L P S + + L+C+ G P V W +G + D + +H DG L+
Sbjct: 4042 LLPLSDKVVIDEKCTLKCVV-MGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIALLRMKNI 4100
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHI---------KPYLITGPEDVVAQTGSSVTFQ 222
+ D QC A N G ++ K + KP + +D T + T +
Sbjct: 4101 KKDKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTTTDHA-TLK 4159
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG-EYSCEAENSVGAV 281
C V G PLPDV + N + +DG + + + +EG C N G+
Sbjct: 4160 CIVVGTPLPDVSCSFNGVTDNSKIRS----EDGIVLIQVNDVTEEGIVVECTISNETGSS 4215
Query: 282 SASGYLTVYDPPSINLS-PNSVNVESGNV--ARFTCTATG---RPEPTMFWSVEGNRTII 335
+++ + + N P V ++G+V R G PEPT+FW G ++I
Sbjct: 4216 TSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEPTLFWKHNG-KSIE 4274
Query: 336 FPGMSRDKYHATAVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
G D Y +F DG+ +L + + D + C A N G + V + + +
Sbjct: 4275 EGG---DYY---LIFEDGIGILKVFNI--QDGSHEFTCIAKNEYGQTTVEIPVEIGLKTE 4326
Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
++ N + + A W+ +G+ L + +T D +
Sbjct: 4327 NKLTLVKT--LNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILEDDSSHKITVDKCIST 4384
Query: 455 KDLDKSDSGT--YTCVASSRHGK 475
L ++GT TC S+ K
Sbjct: 4385 LQLKLEETGTRIITCEVSNSSSK 4407
Score = 46.0 bits (104), Expect = 2e-04
Identities = 62/281 (22%), Positives = 104/281 (37%), Gaps = 14/281 (4%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
T + P P D+T ++ + G P+P I W+K + S + I G
Sbjct: 15594 TESKKPAFTNAPTDLTAVKNGKTKITAEFTGHPAPEIHWFKNKKEIFSGKRQWIENIAGA 15653
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA--QGDT 124
L R D G Y N+ G+ + L + L E R++ + +G+T
Sbjct: 15654 TSLTIGEMR-EDDEGEYKIVVKNTAGSV-EHSCKLTMDQLPEINRVDRYASTLVFDKGET 15711
Query: 125 VVLECLPPRGSPEPNVYW-KKNGQTLLFDGDSRMH-LVDGGNLVIQDARQTDAGRYQCIA 182
V L L G P+P V W NG+ + ++ V L I D G +
Sbjct: 15712 VKLR-LSFSGRPQPEVIWIDNNGKVIEESRKMKIEKTVLNTVLTINSIDSQDQGEFALKI 15770
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRRS 238
+N G + AI +++ +P G V Q SV + GG P+ +
Sbjct: 15771 KNRCGEDKYAIG-IQVTDRP-AAPGKPAVEDQNVDSVRLRWAAPTNDGGSPVRNYTVEMC 15828
Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
G + +V + L N++ + + A+N+ G
Sbjct: 15829 TEKGK-TWTKAEVTKQAFITLFNLVPGESYRFRVRADNTFG 15868
Score = 46.0 bits (104), Expect = 2e-04
Identities = 26/85 (30%), Positives = 43/85 (50%), Gaps = 4/85 (4%)
Query: 209 EDVVAQTGSSV-TFQCRVGGDPLPDVLWRRSAGGGNMPLGRV-KVLDDG--SLRLDNVIL 264
ED+VA G + T C V G P P V W + +P + ++G L + N++
Sbjct: 16275 EDIVANVGDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVE 16334
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV 289
+D G+Y+C A N +G++ L+V
Sbjct: 16335 SDAGKYTCRATNDLGSIMTHAKLSV 16359
Score = 45.6 bits (103), Expect = 2e-04
Identities = 65/264 (24%), Positives = 104/264 (39%), Gaps = 42/264 (15%)
Query: 397 PPIITNGPSNQTLPIKSMA----VFPCTAICTPEPIIAWYFEGEALIQNHRRNV-TNDGT 451
PP+I N T PI A + + P P + GE + + + + N +
Sbjct: 8855 PPVILN---KLTKPITHQAGKSFTYKFNFMGAPAPRLRVLSNGEPVSFDVKYEIYDNIAS 8911
Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKP 510
L + + K D G YT V +++GK + +VD+P+ P R A + +L
Sbjct: 8912 LYIPKMSKRDGGEYTVVLENKYGKDESDLHITMVDTPLKP-----RKAQLVAL------- 8959
Query: 511 ITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQT 570
TDTS T W + G S IL Y V S E SR W I V +
Sbjct: 8960 -----TDTSATFKWLPPHT-GESDILHYIVMRRSTE----------SRRWRNIGH-VQEK 9002
Query: 571 HYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS----NSTEY 626
+ L+P Y F + N G PS + + T+ D ++ G + +
Sbjct: 9003 TFTAIELVPNEFYAFRIVAVNGFGEGAPSEIIEVNTLDYDQEESFDFAGEEELKLDDVQV 9062
Query: 627 RNNILTDHIVELIEATPIDSKTIK 650
N ++T+ +E E T + + +K
Sbjct: 9063 NNEVVTEITIEESEVTIEEHRKLK 9086
Score = 45.2 bits (102), Expect = 3e-04
Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Query: 1 MSDDYVTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59
+SD +TS P +++ P VT + T+ C+ G P PA W K GVL+ ++
Sbjct: 3886 ISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQKYQ- 3944
Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
+ G L+ + D VY C N G S + T+ V
Sbjct: 3945 VTTEDGTSILKIESASL-DDKAVYTCTIANEAG-CESTSCTIDV 3986
Score = 44.8 bits (101), Expect = 4e-04
Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-DDGS--LRLDNVILADEGEYSC 272
G V +C + G P P++ W G +P ++ +DG LR+++ ++ DEGEY C
Sbjct: 1693 GEPVQLKCLIAGMPQPEIEWTVD-GDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYCC 1751
Query: 273 EAENSVGAVSASGYL 287
A N G + YL
Sbjct: 1752 TASNVAGTTFSKCYL 1766
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP + + ++ +P L C G P P I W G +V + SI+ G+ L
Sbjct: 1677 QAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCIL 1736
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR 97
R + D G Y C A+N GT S+
Sbjct: 1737 R-IESTLIEDEGEYCCTASNVAGTTFSK 1763
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 7/88 (7%)
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G + C G P+P + W+V+G+ P + D+Y + DGV +L I T D
Sbjct: 1693 GEPVQLKCLIAGMPQPEIEWTVDGD-----PIVPNDEY-SIVYEDGVCILRIESTLIED- 1745
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
C+A N AG++F + L ++ DD
Sbjct: 1746 EGEYCCTASNVAGTTFSKCYLKLSEADD 1773
Score = 41.9 bits (94), Expect = 0.003
Identities = 47/233 (20%), Positives = 83/233 (35%), Gaps = 18/233 (7%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
D + +VI+A+ G E +++ +Y P S + +
Sbjct: 3750 DSEQIVSDVIVAEVGYDEDECSTIADTITSLSSSPLYTAPVFTERLPSSACFANSKLTLE 3809
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
+G P+PT+ W ++ + + S + + +GV+ + + D+N + + C
Sbjct: 3810 VMFSGVPQPTISWLIDDHELV-----SDGERISIKCENGVSAIRFFNVDRN-AGGFLKCR 3863
Query: 374 AVNYAGSS------FVRGKLTVTSDDD----RPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
A N AG +++V SD P + P T + C
Sbjct: 3864 ATNCAGQVETSCEIVAADEISVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSG 3923
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK--DLDKSDSGTYTCVASSRHG 474
P P W +G L + T DGT +LK D YTC ++ G
Sbjct: 3924 QPLPAAMWEKDGVLLDLQKYQVTTEDGTSILKIESASLDDKAVYTCTIANEAG 3976
Score = 41.5 bits (93), Expect = 0.004
Identities = 115/501 (22%), Positives = 183/501 (36%), Gaps = 55/501 (10%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG---NLVIQDARQTDAGR 177
+GD V +E + + V WK NG+ D +SR H + L+I + TD+G
Sbjct: 13887 RGDNVEIEA--ELLAEDDTVTWKVNGKDA--DLNSRCHEMSHTFFRTLIIDEVEPTDSGM 13942
Query: 178 YQCIARNAAGTRESAIATLKIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGD-PLPDVL 234
+ A GT ES LK+ P ++ P + G VT + + V+
Sbjct: 13943 -EITA--TCGT-ESHTTILKVEELPVDFVKYLPRKTSGKEGQEVTISVTLNHPIDISKVV 13998
Query: 235 WRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
W + G + + + +D SL L D G+Y + V S +L++
Sbjct: 13999 WLKD--GKPLEINKDYSIDTVGCSVSLTLRRAKYEDSGKYKVVCDG----VDCSTHLSIQ 14052
Query: 291 DPPSI-NLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHAT 347
P + N+S + V+ + PE + +V+G + + F G SR
Sbjct: 14053 GKPVLKNVSETKPVITVDKDDQFSLLVAYDSNPEASFSMTVDG-KDLEFDGRSR----ID 14107
Query: 348 AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
V DG+ LT K D+ V N G + + V P + +
Sbjct: 14108 VVDDGLK-LTKRGVSKTDAGEYEV-KLKNEFGEVAQKFDVKVNDTPSAPGDVSVVKAESD 14165
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
L I+ A +I G + V+ DL+
Sbjct: 14166 CLHIEWTAPTEDNGAEVTSYVIEKKESGRRKFHKVATVNGKKTSYVVDDLEIETPYIVRI 14225
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
A ++ G +G + P+ F V ++ PPT NVT TS +LSW +
Sbjct: 14226 AAVNKFG----TGEFIETKPVQTGSPF----QVPTVEFPPT---IDNVTSTSCSLSWPKP 14274
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
+ G S + GY +V+ RE G N V + V++L G Y F +
Sbjct: 14275 IEDGGSPVYGY--DVYKREN-EGEWQKMNGE------ELVFTESFNVRALSSGKEYEFKI 14325
Query: 588 RTENSHGL-SGPSPVSDSVTV 607
N GL S + VS +TV
Sbjct: 14326 EACNEAGLRSNSNVVSKKLTV 14346
Score = 39.9 bits (89), Expect = 0.011
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAGG 65
AP I+E + Q +L C+ +PS A+ W K V V D ++L G
Sbjct: 820 APKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGV 879
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
L DAG+Y C ATN +GTA +
Sbjct: 880 CELLNPEC--FAEDAGLYKCTATNPHGTAET 908
Score = 38.7 bits (86), Expect = 0.025
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
G+ V L+CL G P+P + W +G ++ + + + DG ++ I+ D G Y C
Sbjct: 1693 GEPVQLKCLIA-GMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYCC 1751
Query: 181 IARNAAGT 188
A N AGT
Sbjct: 1752 TASNVAGT 1759
Score = 38.7 bits (86), Expect = 0.025
Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 9/132 (6%)
Query: 160 VDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL-KIHIKPYLITGPEDVVAQTGSS 218
+DGG LV + + D G +C S I +IH + DV + G +
Sbjct: 12243 LDGGKLVFE--AKNDYGVDKCTILLDVRDSGSFIEDYSEIHRSAEIQNSVGDVQVKEGET 12300
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV-LD---DGSL--RLDNVILADEGEYSC 272
RV G PLP+++W ++ +M + K LD DG R+ N D+ +YS
Sbjct: 12301 AKLTGRVDGFPLPELIWIKNGKEIDMMVPSTKYQLDYHSDGEFEARIANCTFEDDDDYSL 12360
Query: 273 EAENSVGAVSAS 284
EN G S +
Sbjct: 12361 LVENLAGVDSCN 12372
Score = 37.9 bits (84), Expect = 0.043
Identities = 44/186 (23%), Positives = 80/186 (43%), Gaps = 14/186 (7%)
Query: 114 PESKQSAQGDT-VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR- 171
P+S Q ++ V+++C P + W NG LL D M V G V++ +
Sbjct: 8771 PKSHAVGQMNSEVIIKC--KTSQPISDAKWFCNGMVLLPDEQVNM-TVTGCEAVLRLVKF 8827
Query: 172 -QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-PEDVVAQTGSSVTFQCRVGGDP 229
+ G Y + + G++ A L + P ++ + + Q G S T++ G P
Sbjct: 8828 LPQNKGNYHVLIDGSIGSQP---AILSGPVPPVILNKLTKPITHQAGKSFTYKFNFMGAP 8884
Query: 230 LPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P + R + G + + ++ D+ SL + + D GEY+ EN G + ++
Sbjct: 8885 APRL--RVLSNGEPVSFDVKYEIYDNIASLYIPKMSKRDGGEYTVVLENKYGKDESDLHI 8942
Query: 288 TVYDPP 293
T+ D P
Sbjct: 8943 TMVDTP 8948
Score = 37.9 bits (84), Expect = 0.043
Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 14/106 (13%)
Query: 508 TKPITHNVTDT---SVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564
+KP + VT T +VTL+WS ++ S++ Y VE R+T+ G A
Sbjct: 10460 SKPTSLQVTSTERETVTLTWSLPTELNGSNVNEYLVE---RKTVDGGRWRH--------A 10508
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
V + VV L G Y+F V N G S PS ++ T ++
Sbjct: 10509 CTVTDSRAVVDGLFSGTEYVFRVVAVNGAGQSAPSDTIEATTQAEE 10554
Score = 37.9 bits (84), Expect = 0.043
Identities = 44/189 (23%), Positives = 69/189 (36%), Gaps = 21/189 (11%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRV--- 76
D+ + P TL+C GSP P + W + + H+ L + + G+V
Sbjct: 17684 DMGIVNGHPTTLSCNVTGSPEPTLEW----IYIDDSGHKINLTSSTTDWTECRFGKVAEL 17739
Query: 77 ------HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLE-- 128
G Y C ATNS G A ++ L V L +E P + Q L+
Sbjct: 17740 KSERVLREQRGTYQCIATNSSGQATTQ-CYLLVGELSDEPAGPPRFVKCLQDTWTPLKES 17798
Query: 129 ---CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIAR 183
+ G P P++ W N + + D ++ L I++ G Y A
Sbjct: 17799 IEFSVELAGFPTPDLTWYHNEKKINEGKDVKITFPSDTTSVLSIKNVSLASLGMYFVEAS 17858
Query: 184 NAAGTRESA 192
N G +A
Sbjct: 17859 NIHGVLRTA 17867
Score = 37.1 bits (82), Expect = 0.076
Identities = 28/111 (25%), Positives = 52/111 (46%), Gaps = 11/111 (9%)
Query: 183 RNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
R A +R + K +KP P V+ + S+ + + G+P+P V W + G
Sbjct: 17995 RAAINSRNKRVCRPKFMVKPK----PRKVLEEY-KSLRLKTAISGNPMPQVHWDKE--GI 18047
Query: 243 NMPLG-RVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
+ G + + +DG L + +V D+G Y+C A N+ G ++ + + V
Sbjct: 18048 ILETGNKYSIYNDGDFYYLEVHHVSTFDKGFYNCTAANNEGIITCTSEIDV 18098
Score = 35.5 bits (78), Expect = 0.23
Identities = 26/105 (24%), Positives = 46/105 (43%), Gaps = 14/105 (13%)
Query: 509 KPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVH 568
KP + T TS+ L W+ +N + Y V++ + R W V+A+ +
Sbjct: 15506 KPEYVSSTATSIALKWTSDN-----DEVTYTVQM---------KEANSKRPWAVVAKEIS 15551
Query: 569 QTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ + L G +Y+F V +N G + S S+S+ D + S
Sbjct: 15552 ECSATIAQLKEGTSYLFRVIAQNKTGQTVTSEQSESIECKDTTES 15596
Score = 34.7 bits (76), Expect = 0.40
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 7/87 (8%)
Query: 112 LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKK---NGQTLLFDGDSRMHLVDGG--NL 165
+EP S G + L C +P V W K N + + + D ++DGG L
Sbjct: 824 VEPLHSASFLDGQAMSLRC-KITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGVCEL 882
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESA 192
+ + DAG Y+C A N GT E+A
Sbjct: 883 LNPECFAEDAGLYKCTATNPHGTAETA 909
Score = 34.3 bits (75), Expect = 0.53
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTND-GT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P + WYF E L + ++ + GT ++LK++ K G Y A + HG+ +
Sbjct: 1162 PTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKRQGGNYFLRAHNCHGESILPMK 1221
Query: 482 LLVDSPINPNIH 493
L VD PI H
Sbjct: 1222 LTVD-PIEAVTH 1232
Score = 34.3 bits (75), Expect = 0.53
Identities = 48/218 (22%), Positives = 86/218 (39%), Gaps = 12/218 (5%)
Query: 7 TSGEAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
T G IIE P V + + + C+ S A +W+ G++++ D ++ G
Sbjct: 8760 TIGTGQSIIEHPKSHAVGQMNSEVIIKCKTSQPISDA-KWFCNGMVLLPDEQVNMTVTGC 8818
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + + G Y S G+ + + V+ + +P + Q+ + T
Sbjct: 8819 EAVLRLVK-FLPQNKGNYHVLIDGSIGSQPAILSGPVPPVILNKL-TKPITHQAGKSFTY 8876
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184
+ G+P P + NG+ + F D + + D +L I + D G Y + N
Sbjct: 8877 KFNFM---GAPAPRLRVLSNGEPVSF--DVKYEIYDNIASLYIPKMSKRDGGEYTVVLEN 8931
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
G ES + + L +VA T +S TF+
Sbjct: 8932 KYGKDESDLHITMVDTP--LKPRKAQLVALTDTSATFK 8967
Score = 34.3 bits (75), Expect = 0.53
Identities = 15/43 (34%), Positives = 19/43 (44%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG 49
T G P E P+ V A L G+P+PA RW+ G
Sbjct: 18424 TVGAKPKFNESPISVQTCEKNRAELRASFSGTPAPACRWFYNG 18466
Score = 33.9 bits (74), Expect = 0.71
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 135 SPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
S P ++ W N +++L D D R + G N+ + + G Y+C+ RN AG S
Sbjct: 115 SDPPAIFEWFYNEKSVLQDRD-RFQVGHGINISRLKVSRPEQGVYKCVTRNPAGVSTSYG 173
Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTF 221
+ +L + ED+ Q SVT+
Sbjct: 174 YITVNADREHLSSSKEDMRLQRQHSVTY 201
Score = 33.9 bits (74), Expect = 0.71
Identities = 17/39 (43%), Positives = 20/39 (51%), Gaps = 1/39 (2%)
Query: 504 PGPPTKPITHN-VTDTSVTLSWSQNNKIGSSSILGYQVE 541
PG PT PI + VT++S SW G I GY VE
Sbjct: 15380 PGIPTGPIVFDDVTESSAEFSWKAPENNGGCEITGYNVE 15418
Score = 33.5 bits (73), Expect = 0.93
Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 4/75 (5%)
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRR--NVTNDGT--LVLKDLDKSDSGTYTCVA 469
+A C P P + WY + + L + + N+G L +K++ +SD+G YTC A
Sbjct: 16285 IATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYTCRA 16344
Query: 470 SSRHGKYVWSGALLV 484
++ G + L V
Sbjct: 16345 TNDLGSIMTHAKLSV 16359
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Query: 429 IAWYFEGEALIQNHRRNVTN--DGT--LVLKDLDKSDSGTYTCVASSRHG 474
++W +G + +N + V DG L ++ DSG YTC A S HG
Sbjct: 976 VSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDSGVYTCTAESEHG 1025
Score = 33.1 bits (72), Expect = 1.2
Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 2/69 (2%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGRYQ 179
GD + G P P V W K+ + L + G L +++ ++DAG+Y
Sbjct: 16282 GDLIATLSCDVDGVPSPKVQWYKDDKELTVPSMKYDSFYNEGLAELTVKNIVESDAGKYT 16341
Query: 180 CIARNAAGT 188
C A N G+
Sbjct: 16342 CRATNDLGS 16350
Score = 32.7 bits (71), Expect = 1.6
Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDK--SDSGTYTCVASSRHG 474
C P+P I W +G+ ++ N ++ DG +L+ D G Y C AS+ G
Sbjct: 1700 CLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYCCTASNVAG 1758
Score = 30.3 bits (65), Expect = 8.7
Identities = 28/125 (22%), Positives = 47/125 (37%), Gaps = 7/125 (5%)
Query: 243 NMPLGRVKVLDDGSLRLD--NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPN 300
N+ + ++ LD G L + N D+ + +S + Y ++ I S
Sbjct: 12234 NVTINDIRKLDGGKLVFEAKNDYGVDKCTILLDVRDSGSFIE--DYSEIHRSAEIQNSVG 12291
Query: 301 SVNVESGNVARFTCTATGRPEPTMFWSVEGNR-TIIFPGMSRD-KYHATAVFDG-VTVLT 357
V V+ G A+ T G P P + W G ++ P YH+ F+ + T
Sbjct: 12292 DVQVKEGETAKLTGRVDGFPLPELIWIKNGKEIDMMVPSTKYQLDYHSDGEFEARIANCT 12351
Query: 358 INDTD 362
D D
Sbjct: 12352 FEDDD 12356
>AF022977-1|ABF71715.1| 1285|Caenorhabditis elegans Peroxidasin
(drosophila peroxidase)homolog protein 1 protein.
Length = 1285
Score = 106 bits (254), Expect = 1e-22
Identities = 63/183 (34%), Positives = 88/183 (48%), Gaps = 4/183 (2%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F +P +G V + C G+P+P + W NG+ + ++ L L I
Sbjct: 316 QFTYKPRDNSFREGSEVKVNC-EVMGNPKPTINWYHNGKRFISSRKRQLGL-SNNVLRIY 373
Query: 169 DARQTDAGRYQCIARNAAG-TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG 227
+ D+GRY C A N+ G R + L + P + GP+ V G SV F C+ G
Sbjct: 374 PFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANG 433
Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGY 286
+P+PD W GR V DDG+ LR+ N+ DEG YSC A N VGA+SA
Sbjct: 434 NPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAGNPVGAMSADAK 493
Query: 287 LTV 289
LTV
Sbjct: 494 LTV 496
Score = 81.4 bits (192), Expect = 4e-15
Identities = 63/196 (32%), Positives = 85/196 (43%), Gaps = 10/196 (5%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDN 261
P P D + GS V C V G+P P + W + R L + LR+
Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYP 374
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINLSPNSVNVESGNVARFTCTATGR 319
+ D G Y+CEA NSVG V + L + PP+I P SV+ G F C A G
Sbjct: 375 FLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVCKANGN 434
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
P P WS +G+ TI G + ++ V D T L I++ +K D C A N G
Sbjct: 435 PVPDYTWSFDGS-TI---GHIKGRF---MVSDDGTELRISNIEKKD-EGYYSCMAGNPVG 486
Query: 380 SSFVRGKLTVTSDDDR 395
+ KLTV + R
Sbjct: 487 AMSADAKLTVIGGETR 502
Score = 75.8 bits (178), Expect = 2e-13
Identities = 54/188 (28%), Positives = 80/188 (42%), Gaps = 5/188 (2%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
+P +P D + +NC G+P P I WY G +S R + + + LR
Sbjct: 314 SPQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNV--LR 371
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
+ + D+G Y CEA NS G R + ++ + P+S G +VV C
Sbjct: 372 -IYPFLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIYEGPQSVSQNLGGSVVFVC- 429
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G+P P+ W +G T+ M DG L I + + D G Y C+A N G
Sbjct: 430 KANGNPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAGNPVGAM- 488
Query: 191 SAIATLKI 198
SA A L +
Sbjct: 489 SADAKLTV 496
Score = 64.1 bits (149), Expect = 6e-10
Identities = 53/184 (28%), Positives = 76/184 (41%), Gaps = 14/184 (7%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P P + G+ + C G P+PT+ W G R I SR + +
Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFI----SSRKRQLGLSN--- 367
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
VL I + DS C AVN G L + S PP I GP + + +
Sbjct: 368 -NVLRIYPFLEEDS-GRYTCEAVNSVGKVRHAFSLDLISS---VPPNIYEGPQSVSQNLG 422
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQ-NHRRNVTNDGT-LVLKDLDKSDSGTYTCVAS 470
VF C A P P W F+G + R V++DGT L + +++K D G Y+C+A
Sbjct: 423 GSVVFVCKANGNPVPDYTWSFDGSTIGHIKGRFMVSDDGTELRISNIEKKDEGYYSCMAG 482
Query: 471 SRHG 474
+ G
Sbjct: 483 NPVG 486
Score = 46.8 bits (106), Expect = 9e-05
Identities = 28/97 (28%), Positives = 46/97 (47%), Gaps = 1/97 (1%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKD 456
P T P + + S C + P+P I WY G+ I + +R + ++ L +
Sbjct: 315 PQFTYKPRDNSFREGSEVKVNCEVMGNPKPTINWYHNGKRFISSRKRQLGLSNNVLRIYP 374
Query: 457 LDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIH 493
+ DSG YTC A + GK + +L + S + PNI+
Sbjct: 375 FLEEDSGRYTCEAVNSVGKVRHAFSLDLISSVPPNIY 411
>Z49938-4|CAA90189.3| 2180|Caenorhabditis elegans Hypothetical
protein C09D8.1a protein.
Length = 2180
Score = 102 bits (244), Expect = 2e-21
Identities = 86/309 (27%), Positives = 129/309 (41%), Gaps = 20/309 (6%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRAT 72
++ +P TV + CRA G+P P++ W G + SI A GL LR
Sbjct: 50 LVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFE 109
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE------EFRLEPESKQSAQGDTVV 126
+ +A V C A N A+L V + + L P K QG T
Sbjct: 110 RVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLKSVEQGKTAY 169
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIAR 183
+ C RG P V W ++ L D R + GN L+IQ AR+ D G+Y+CIAR
Sbjct: 170 VSCRV-RGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYECIAR 228
Query: 184 NAAGTRESAIATLKIHIK---PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
N G S A L + ++ PY E V G ++ C G P+P V W+++
Sbjct: 229 NTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWKKT- 287
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINL 297
M L G L + ++C A +++G + A+ + + PP +N+
Sbjct: 288 --DLMVLDDPSTAPIGKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAKELPPPPVNI 345
Query: 298 SPNSVNVES 306
+SV ES
Sbjct: 346 VVSSVTSES 354
Score = 64.9 bits (151), Expect = 3e-10
Identities = 77/286 (26%), Positives = 119/286 (41%), Gaps = 35/286 (12%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGTRE 190
G+P P+V W+ NG+++ + + G ++ R + +A C A N
Sbjct: 73 GNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFERVSLDDNATVVSCSADNGVANPV 132
Query: 191 SAIATL------KIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
A A+L K+ I P + P + G + CRV GDP VLW R +
Sbjct: 133 VAEASLTVVPRDKVPIGFPQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLD 192
Query: 244 MPL-GRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAV---SASGYLTVYDPP--- 293
+ GR V + G+L + + D+G+Y C A N++G +A+ Y+ V P
Sbjct: 193 IRADGRYSVSTIGNPGALMIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYF 252
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
S L V GN+ TC A G P P +FW + P +TA G
Sbjct: 253 SYKLERQYVVGVGGNI-NLTCVAVGYPMPRVFWKKTDLMVLDDP--------STAPI-GK 302
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
VLT+ +S C AV+ G+ + TV + + PPP+
Sbjct: 303 NVLTLTHV---ESTENFTCVAVSALGN--IEATTTVIAKELPPPPV 343
Score = 61.7 bits (143), Expect = 3e-09
Identities = 64/276 (23%), Positives = 110/276 (39%), Gaps = 15/276 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFL 69
P I P +V + + A ++CR G P + W + + + +D S+ G L
Sbjct: 151 PQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGAL 210
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE----EFRLEPESKQSAQGDTV 125
H R D G Y C A N+ G A S+ A L+V V R ++LE + G +
Sbjct: 211 MIQHAR-EEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGV-GGNI 268
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C+ G P P V+WKK +L D + + L + T+ + C+A +A
Sbjct: 269 NLTCVAV-GYPMPRVFWKKTDLMVLDDPSTAP--IGKNVLTLTHVESTE--NFTCVAVSA 323
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGN 243
G E+ + + P + V +T++ + + V +R G
Sbjct: 324 LGNIEATTTVIAKELPPPPVNIVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKYSEGR 383
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
G+ + SL +D ++ E++ + VG
Sbjct: 384 SSRGKTMETLENSLVIDGLVAFQTYEFTVRSAGPVG 419
Score = 52.8 bits (121), Expect = 1e-06
Identities = 47/192 (24%), Positives = 76/192 (39%), Gaps = 13/192 (6%)
Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
DP + + P+S V + F C A G P P++ W V G ++ ++
Sbjct: 46 DPARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSI-----TDHNRISIKSLA 100
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRPP--PIITNGPSNQ 407
G++ L +D+ + CSA N + V LTV D P P I PS +
Sbjct: 101 TGLSTLRFERVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLK 160
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR----NVTNDGTLVLKDLDKSDS 462
++ A C P + W + L I+ R + N G L+++ + D
Sbjct: 161 SVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQ 220
Query: 463 GTYTCVASSRHG 474
G Y C+A + G
Sbjct: 221 GKYECIARNTLG 232
Score = 51.6 bits (118), Expect = 3e-06
Identities = 80/352 (22%), Positives = 138/352 (39%), Gaps = 39/352 (11%)
Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
DSP++ + A +PG P + + L+W + + SS ++GY V +
Sbjct: 521 DSPLSTLV---TVATRQGIPGQPPMLTVKALDSRRMQLTWDK--PLYSSPVVGYTVRYNT 575
Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPG-----ITYMFIVRTENSHGLSGPS 599
+ VV + +Y + T I +T S LS P+
Sbjct: 576 SDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPT 635
Query: 600 PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659
VS + T W+G + N +LT + + DSKT L E +
Sbjct: 636 IVSAAATSSKSVEIRWKGP----EQKKLNGVLTAYRINYFRLE--DSKTANL--ESVE-- 685
Query: 660 YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719
Y +D+ + + +++ +D + + ++ L Y+ YE + G S
Sbjct: 686 -------YDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPES 738
Query: 720 NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV----VVNW-- 773
+ RV +TL+DVP P N + + T+V L W P NG + GY V +VN
Sbjct: 739 SIRVVKTLEDVPSAPR-NFNAELTSATSVKLTWDAP--AAANGALLGYYVYLDRMVNGEP 795
Query: 774 -LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824
++ + K +V I + + L +L YS ++ A G G FS++
Sbjct: 796 VVEKGSKKRIVMIRDSSKRYFEL--DSLDPNTEYSFRLNAFNRNGDGEFSER 845
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Query: 715 EGKPSNS-RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
EG+ N+ T PDG PI+++ ++ V + W PP + +NG IT Y +++
Sbjct: 940 EGRSQNATETIATPVGSPDGEPIDVQYEVMKGKIV-VSWRPPSEEKRNGNITSYKAILSA 998
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
+D A++ + +S N+ +Y ++AA T+ G+GP+S + N D
Sbjct: 999 MDATADRYEQPV--PAPSTSSTFEVNVRR--AYLFKVAAATMKGIGPYSPVLTINPD 1051
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV--H 749
FE+ SL T+Y F L F + +G+ S + T P+ P I + V
Sbjct: 816 FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLDRDEPPVVAR 875
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
++W P+++ I YN+ + P S V T S ++ L GV Y V
Sbjct: 876 IEWKMPKMKPNETPIEKYNLWLRAQGYP--DSYVKAKTVDGTDLSTTISGLWMGVVYDVL 933
Query: 810 IAAE 813
+AAE
Sbjct: 934 LAAE 937
Score = 34.7 bits (76), Expect = 0.40
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
I L + YEF + G S AQT P P++ + LN ++ +KW
Sbjct: 399 IDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWG 458
Query: 754 PPELQLQNGIITGYNV 769
P E NG+ITGY V
Sbjct: 459 PCE--QPNGLITGYKV 472
>Z46811-1|CAA86842.3| 2180|Caenorhabditis elegans Hypothetical
protein C09D8.1a protein.
Length = 2180
Score = 102 bits (244), Expect = 2e-21
Identities = 86/309 (27%), Positives = 129/309 (41%), Gaps = 20/309 (6%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRAT 72
++ +P TV + CRA G+P P++ W G + SI A GL LR
Sbjct: 50 LVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFE 109
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE------EFRLEPESKQSAQGDTVV 126
+ +A V C A N A+L V + + L P K QG T
Sbjct: 110 RVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLKSVEQGKTAY 169
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIAR 183
+ C RG P V W ++ L D R + GN L+IQ AR+ D G+Y+CIAR
Sbjct: 170 VSCRV-RGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYECIAR 228
Query: 184 NAAGTRESAIATLKIHIK---PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
N G S A L + ++ PY E V G ++ C G P+P V W+++
Sbjct: 229 NTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWKKT- 287
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINL 297
M L G L + ++C A +++G + A+ + + PP +N+
Sbjct: 288 --DLMVLDDPSTAPIGKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAKELPPPPVNI 345
Query: 298 SPNSVNVES 306
+SV ES
Sbjct: 346 VVSSVTSES 354
Score = 64.9 bits (151), Expect = 3e-10
Identities = 77/286 (26%), Positives = 119/286 (41%), Gaps = 35/286 (12%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGTRE 190
G+P P+V W+ NG+++ + + G ++ R + +A C A N
Sbjct: 73 GNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFERVSLDDNATVVSCSADNGVANPV 132
Query: 191 SAIATL------KIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
A A+L K+ I P + P + G + CRV GDP VLW R +
Sbjct: 133 VAEASLTVVPRDKVPIGFPQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLD 192
Query: 244 MPL-GRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAV---SASGYLTVYDPP--- 293
+ GR V + G+L + + D+G+Y C A N++G +A+ Y+ V P
Sbjct: 193 IRADGRYSVSTIGNPGALMIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYF 252
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
S L V GN+ TC A G P P +FW + P +TA G
Sbjct: 253 SYKLERQYVVGVGGNI-NLTCVAVGYPMPRVFWKKTDLMVLDDP--------STAPI-GK 302
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
VLT+ +S C AV+ G+ + TV + + PPP+
Sbjct: 303 NVLTLTHV---ESTENFTCVAVSALGN--IEATTTVIAKELPPPPV 343
Score = 61.7 bits (143), Expect = 3e-09
Identities = 64/276 (23%), Positives = 110/276 (39%), Gaps = 15/276 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFL 69
P I P +V + + A ++CR G P + W + + + +D S+ G L
Sbjct: 151 PQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGAL 210
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE----EFRLEPESKQSAQGDTV 125
H R D G Y C A N+ G A S+ A L+V V R ++LE + G +
Sbjct: 211 MIQHAR-EEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGV-GGNI 268
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C+ G P P V+WKK +L D + + L + T+ + C+A +A
Sbjct: 269 NLTCVAV-GYPMPRVFWKKTDLMVLDDPSTAP--IGKNVLTLTHVESTE--NFTCVAVSA 323
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGN 243
G E+ + + P + V +T++ + + V +R G
Sbjct: 324 LGNIEATTTVIAKELPPPPVNIVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKYSEGR 383
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
G+ + SL +D ++ E++ + VG
Sbjct: 384 SSRGKTMETLENSLVIDGLVAFQTYEFTVRSAGPVG 419
Score = 52.8 bits (121), Expect = 1e-06
Identities = 47/192 (24%), Positives = 76/192 (39%), Gaps = 13/192 (6%)
Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
DP + + P+S V + F C A G P P++ W V G ++ ++
Sbjct: 46 DPARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSI-----TDHNRISIKSLA 100
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRPP--PIITNGPSNQ 407
G++ L +D+ + CSA N + V LTV D P P I PS +
Sbjct: 101 TGLSTLRFERVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLK 160
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR----NVTNDGTLVLKDLDKSDS 462
++ A C P + W + L I+ R + N G L+++ + D
Sbjct: 161 SVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQ 220
Query: 463 GTYTCVASSRHG 474
G Y C+A + G
Sbjct: 221 GKYECIARNTLG 232
Score = 51.6 bits (118), Expect = 3e-06
Identities = 80/352 (22%), Positives = 138/352 (39%), Gaps = 39/352 (11%)
Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
DSP++ + A +PG P + + L+W + + SS ++GY V +
Sbjct: 521 DSPLSTLV---TVATRQGIPGQPPMLTVKALDSRRMQLTWDK--PLYSSPVVGYTVRYNT 575
Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPG-----ITYMFIVRTENSHGLSGPS 599
+ VV + +Y + T I +T S LS P+
Sbjct: 576 SDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPT 635
Query: 600 PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659
VS + T W+G + N +LT + + DSKT L E +
Sbjct: 636 IVSAAATSSKSVEIRWKGP----EQKKLNGVLTAYRINYFRLE--DSKTANL--ESVE-- 685
Query: 660 YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719
Y +D+ + + +++ +D + + ++ L Y+ YE + G S
Sbjct: 686 -------YDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPES 738
Query: 720 NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV----VVNW-- 773
+ RV +TL+DVP P N + + T+V L W P NG + GY V +VN
Sbjct: 739 SIRVVKTLEDVPSAPR-NFNAELTSATSVKLTWDAP--AAANGALLGYYVYLDRMVNGEP 795
Query: 774 -LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824
++ + K +V I + + L +L YS ++ A G G FS++
Sbjct: 796 VVEKGSKKRIVMIRDSSKRYFEL--DSLDPNTEYSFRLNAFNRNGDGEFSER 845
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Query: 715 EGKPSNS-RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
EG+ N+ T PDG PI+++ ++ V + W PP + +NG IT Y +++
Sbjct: 940 EGRSQNATETIATPVGSPDGEPIDVQYEVMKGKIV-VSWRPPSEEKRNGNITSYKAILSA 998
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
+D A++ + +S N+ +Y ++AA T+ G+GP+S + N D
Sbjct: 999 MDATADRYEQPV--PAPSTSSTFEVNVRR--AYLFKVAAATMKGIGPYSPVLTINPD 1051
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV--H 749
FE+ SL T+Y F L F + +G+ S + T P+ P I + V
Sbjct: 816 FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLDRDEPPVVAR 875
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
++W P+++ I YN+ + P S V T S ++ L GV Y V
Sbjct: 876 IEWKMPKMKPNETPIEKYNLWLRAQGYP--DSYVKAKTVDGTDLSTTISGLWMGVVYDVL 933
Query: 810 IAAE 813
+AAE
Sbjct: 934 LAAE 937
Score = 34.7 bits (76), Expect = 0.40
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
I L + YEF + G S AQT P P++ + LN ++ +KW
Sbjct: 399 IDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWG 458
Query: 754 PPELQLQNGIITGYNV 769
P E NG+ITGY V
Sbjct: 459 PCE--QPNGLITGYKV 472
>AF316539-1|AAK01632.1| 2200|Caenorhabditis elegans PTP-3A protein.
Length = 2200
Score = 102 bits (244), Expect = 2e-21
Identities = 86/309 (27%), Positives = 129/309 (41%), Gaps = 20/309 (6%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP-AGGLFFLRAT 72
++ +P TV + CRA G+P P++ W G + SI A GL LR
Sbjct: 50 LVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFE 109
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE------EFRLEPESKQSAQGDTVV 126
+ +A V C A N A+L V + + L P K QG T
Sbjct: 110 RVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLKSVEQGKTAY 169
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIAR 183
+ C RG P V W ++ L D R + GN L+IQ AR+ D G+Y+CIAR
Sbjct: 170 VSCRV-RGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQGKYECIAR 228
Query: 184 NAAGTRESAIATLKIHIK---PYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSA 239
N G S A L + ++ PY E V G ++ C G P+P V W+++
Sbjct: 229 NTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGVGGNINLTCVAVGYPMPRVFWKKT- 287
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD--PPSINL 297
M L G L + ++C A +++G + A+ + + PP +N+
Sbjct: 288 --DLMVLDDPSTAPIGKNVLTLTHVESTENFTCVAVSALGNIEATTTVIAKELPPPPVNI 345
Query: 298 SPNSVNVES 306
+SV ES
Sbjct: 346 VVSSVTSES 354
Score = 64.9 bits (151), Expect = 3e-10
Identities = 77/286 (26%), Positives = 119/286 (41%), Gaps = 35/286 (12%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGTRE 190
G+P P+V W+ NG+++ + + G ++ R + +A C A N
Sbjct: 73 GNPLPSVIWRVNGKSITDHNRISIKSLATGLSTLRFERVSLDDNATVVSCSADNGVANPV 132
Query: 191 SAIATL------KIHIK-PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGN 243
A A+L K+ I P + P + G + CRV GDP VLW R +
Sbjct: 133 VAEASLTVVPRDKVPIGFPQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLD 192
Query: 244 MPL-GRVKVL---DDGSLRLDNVILADEGEYSCEAENSVGAV---SASGYLTVYDPP--- 293
+ GR V + G+L + + D+G+Y C A N++G +A+ Y+ V P
Sbjct: 193 IRADGRYSVSTIGNPGALMIQHAREEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYF 252
Query: 294 SINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
S L V GN+ TC A G P P +FW + P +TA G
Sbjct: 253 SYKLERQYVVGVGGNI-NLTCVAVGYPMPRVFWKKTDLMVLDDP--------STAPI-GK 302
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPI 399
VLT+ +S C AV+ G+ + TV + + PPP+
Sbjct: 303 NVLTLTHV---ESTENFTCVAVSALGN--IEATTTVIAKELPPPPV 343
Score = 61.7 bits (143), Expect = 3e-09
Identities = 64/276 (23%), Positives = 110/276 (39%), Gaps = 15/276 (5%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL--VVSDTHRSILPAGGLFFL 69
P I P +V + + A ++CR G P + W + + + +D S+ G L
Sbjct: 151 PQIELHPSLKSVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGAL 210
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLRE----EFRLEPESKQSAQGDTV 125
H R D G Y C A N+ G A S+ A L+V V R ++LE + G +
Sbjct: 211 MIQHAR-EEDQGKYECIARNTLGVAHSKAANLYVKVRRVPPYFSYKLERQYVVGV-GGNI 268
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
L C+ G P P V+WKK +L D + + L + T+ + C+A +A
Sbjct: 269 NLTCVAV-GYPMPRVFWKKTDLMVLDDPSTAP--IGKNVLTLTHVESTE--NFTCVAVSA 323
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD--VLWRRSAGGGN 243
G E+ + + P + V +T++ + + V +R G
Sbjct: 324 LGNIEATTTVIAKELPPPPVNIVVSSVTSESVVITWKPPKYNEAINKYVVNYRLKYSEGR 383
Query: 244 MPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
G+ + SL +D ++ E++ + VG
Sbjct: 384 SSRGKTMETLENSLVIDGLVAFQTYEFTVRSAGPVG 419
Score = 52.8 bits (121), Expect = 1e-06
Identities = 47/192 (24%), Positives = 76/192 (39%), Gaps = 13/192 (6%)
Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
DP + + P+S V + F C A G P P++ W V G ++ ++
Sbjct: 46 DPARLVVRPDSSTVVDESKISFFCRADGNPLPSVIWRVNGKSI-----TDHNRISIKSLA 100
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFV-RGKLTVTSDDDRPP--PIITNGPSNQ 407
G++ L +D+ + CSA N + V LTV D P P I PS +
Sbjct: 101 TGLSTLRFERVSLDDNATVVSCSADNGVANPVVAEASLTVVPRDKVPIGFPQIELHPSLK 160
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRR----NVTNDGTLVLKDLDKSDS 462
++ A C P + W + L I+ R + N G L+++ + D
Sbjct: 161 SVEQGKTAYVSCRVRGDPRAKVLWLRDLIPLDIRADGRYSVSTIGNPGALMIQHAREEDQ 220
Query: 463 GTYTCVASSRHG 474
G Y C+A + G
Sbjct: 221 GKYECIARNTLG 232
Score = 51.6 bits (118), Expect = 3e-06
Identities = 80/352 (22%), Positives = 138/352 (39%), Gaps = 39/352 (11%)
Query: 485 DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFS 544
DSP++ + A +PG P + + L+W + + SS ++GY V +
Sbjct: 521 DSPLSTLV---TVATRQGIPGQPPMLTVKALDSRRMQLTWDK--PLYSSPVVGYTVRYNT 575
Query: 545 RETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPG-----ITYMFIVRTENSHGLSGPS 599
+ VV + +Y + T I +T S LS P+
Sbjct: 576 SDGEKELTLTSPHEKHVVTGLHPDKYYYFRVAAYSDRGQGEFTEPMISKTIASIPLSSPT 635
Query: 600 PVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDSKTIKLMWEILNFY 659
VS + T W+G + N +LT + + DSKT L E +
Sbjct: 636 IVSAAATSSKSVEIRWKGP----EQKKLNGVLTAYRINYFRLE--DSKTANL--ESVE-- 685
Query: 660 YLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPS 719
Y +D+ + + +++ +D + + ++ L Y+ YE + G S
Sbjct: 686 -------YDEDMDDSSSFLDRMSVVVPSDATSYVLSDLLPYSSYEITVAASTMDGYGPES 738
Query: 720 NSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV----VVNW-- 773
+ RV +TL+DVP P N + + T+V L W P NG + GY V +VN
Sbjct: 739 SIRVVKTLEDVPSAPR-NFNAELTSATSVKLTWDAP--AAANGALLGYYVYLDRMVNGEP 795
Query: 774 -LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQK 824
++ + K +V I + + L +L YS ++ A G G FS++
Sbjct: 796 VVEKGSKKRIVMIRDSSKRYFEL--DSLDPNTEYSFRLNAFNRNGDGEFSER 845
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Query: 715 EGKPSNS-RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
EG+ N+ T PDG PI+++ ++ V + W PP + +NG IT Y +++
Sbjct: 940 EGRSQNATETIATPVGSPDGEPIDVQYEVMKGKIV-VSWRPPSEEKRNGNITSYKAILSA 998
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
+D A++ + +S N+ +Y ++AA T+ G+GP+S + N D
Sbjct: 999 MDATADRYEQPV--PAPSTSSTFEVNVRR--AYLFKVAAATMKGIGPYSPVLTINPD 1051
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV--H 749
FE+ SL T+Y F L F + +G+ S + T P+ P I + V
Sbjct: 816 FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLDRDEPPVVAR 875
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
++W P+++ I YN+ + P S V T S ++ L GV Y V
Sbjct: 876 IEWKMPKMKPNETPIEKYNLWLRAQGYP--DSYVKAKTVDGTDLSTTISGLWMGVVYDVL 933
Query: 810 IAAE 813
+AAE
Sbjct: 934 LAAE 937
Score = 34.7 bits (76), Expect = 0.40
Identities = 25/76 (32%), Positives = 34/76 (44%), Gaps = 2/76 (2%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWS 753
I L + YEF + G S AQT P P++ + LN ++ +KW
Sbjct: 399 IDGLVAFQTYEFTVRSAGPVGVGLESLPVEAQTKPSKPATAPVSPQARSLNRDSILVKWG 458
Query: 754 PPELQLQNGIITGYNV 769
P E NG+ITGY V
Sbjct: 459 PCE--QPNGLITGYKV 472
>AY724774-1|AAU21474.1| 750|Caenorhabditis elegans UNC-89-B
protein.
Length = 750
Score = 100 bits (240), Expect = 5e-21
Identities = 113/444 (25%), Positives = 176/444 (39%), Gaps = 68/444 (15%)
Query: 213 AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRL--DNVILADEG 268
A+ G SVTF+C G+P P + W + G ++K+ DG+ RL +V EG
Sbjct: 15 AKPGDSVTFECLPFGNPFPSIKWLKD-GLELFSDEKIKMEAAADGTQRLILSDVTFLSEG 73
Query: 269 EYSCEAENSVGAVSASGYLTVYDP--------PSINLSPN-----------SVNVESGNV 309
+ C A N G S L + P +N P ++++ GNV
Sbjct: 74 YFRCVATNEHGTASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMSIHEGNV 133
Query: 310 ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNT 369
ATG P PT+ W +G + I+ G + T G+ L I + +D
Sbjct: 134 VEMIVCATGIPTPTVKWYKDG-QEIVGDGPDGKRVIFTDE-RGIHHLVIVNASPDD-EGE 190
Query: 370 IVCSAVNYAGSSFVRGKLT------VTSDDDRP----PPIITNGPSNQTLPIKSMAVFPC 419
A N GS+ G L + D+R PP N+ + +F C
Sbjct: 191 YSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMPTIFDC 250
Query: 420 TAICTPEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVASSRHGK 475
+ P P + W+ G+ ++ R + + G L++ D D+G Y A + HG
Sbjct: 251 LVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATAKNSHGS 310
Query: 476 YVWSGALLVDSPINPNIHF---------------FRAADVSSLPGPPTK-PITHNVTDTS 519
S L V P +I F F+ + +SLP PP + P VT
Sbjct: 311 ASSSAVLDVTVPFLDSIKFNGEIDVTPYLTEEYGFKKLNTASLPTPPDRGPFIKEVTGHY 370
Query: 520 VTLSWSQNNKIGSS-SILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLI 578
+TLSW + + Y +E+ RE + W ++ + + V++L
Sbjct: 371 LTLSWIPTKRAPPRYPQVTYVIEI--REL--------PEKQWSLLEYNIPEPVCKVRNLE 420
Query: 579 PGITYMFIVRTENSHGLSGPSPVS 602
G +Y F VR EN +G+S PSP S
Sbjct: 421 LGKSYQFRVRAENIYGISDPSPAS 444
Score = 73.7 bits (173), Expect = 7e-13
Identities = 95/318 (29%), Positives = 135/318 (42%), Gaps = 51/318 (16%)
Query: 21 VTVARHQPA---TLNCRAGGSPSPAIRWYKGGVLVVSDTH-RSILPAGGLFFLRATHGRV 76
+T+ R +P T C G+P P+I+W K G+ + SD + A G L +
Sbjct: 10 LTIRRAKPGDSVTFECLPFGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTF 69
Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAVLR-------EEFRLEPES----------KQS 119
S+ G + C ATN +GTA S A L + R E EPE S
Sbjct: 70 LSE-GYFRCVATNEHGTA-STKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMS 127
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV---DGG--NLVIQDARQTD 174
VV + G P P V W K+GQ ++ DG ++ + G +LVI +A D
Sbjct: 128 IHEGNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNASPDD 187
Query: 175 AGRYQCIARNAAGTRESAIATLKIHIKPYLITG---------PEDVVAQTGSS------- 218
G Y A N G+ ++ +L I I+P I P V Q +
Sbjct: 188 EGEYSLEATNKLGSAKTE-GSLNI-IRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMP 245
Query: 219 VTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEA 274
F C V G P P+V W + G +P GR+K+ G +L + + L D GEY A
Sbjct: 246 TIFDCLVVGHPAPEVEWFHN-GKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATA 304
Query: 275 ENSVGAVSASGYLTVYDP 292
+NS G+ S+S L V P
Sbjct: 305 KNSHGSASSSAVLDVTVP 322
Score = 68.5 bits (160), Expect = 3e-11
Identities = 88/316 (27%), Positives = 124/316 (39%), Gaps = 50/316 (15%)
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTD 174
+++ GD+V ECLP G+P P++ W K+G L D +M G L++ D
Sbjct: 13 RRAKPGDSVTFECLP-FGNPFPSIKWLKDGLELFSDEKIKMEAAADGTQRLILSDVTFLS 71
Query: 175 AGRYQCIARNAAGTRESAIATLKI-------------------HIKPYLITGPEDVVAQT 215
G ++C+A N GT S A L I KP + G ++
Sbjct: 72 EGYFRCVATNEHGT-ASTKAELVIEGDRTIGSRPLPEVNGEPEECKPRIRRGLYNMSIHE 130
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDD----GSLRLDNVILADEGE 269
G+ V G P P V W + G+ P G+ + D L + N DEGE
Sbjct: 131 GNVVEMIVCATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNASPDDEGE 190
Query: 270 YSCEAENSVGAVSASGYLTVYDPPSI---------NLSPNSV-NVESGNVAR-----FTC 314
YS EA N +G+ G L + P I P V +++ +V F C
Sbjct: 191 YSLEATNKLGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMPTIFDC 250
Query: 315 TATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSA 374
G P P + W G + I PG R K + G L I DT D+ V +A
Sbjct: 251 LVVGHPAPEVEWFHNGKK--IVPG-GRIKIQSCG--GGSHALIILDTTLEDA-GEYVATA 304
Query: 375 VNYAGSSFVRGKLTVT 390
N GS+ L VT
Sbjct: 305 KNSHGSASSSAVLDVT 320
Score = 64.5 bits (150), Expect = 4e-10
Identities = 54/207 (26%), Positives = 90/207 (43%), Gaps = 15/207 (7%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG---QTLLFDGDSRMHLVDGGN--LVIQD 169
E + A+ DT+ + L G P+P++ WK G T +++ G L I
Sbjct: 496 EKRYCAENDTLTI-VLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITG 554
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
+ + G+YQC A+N G + I + + +P I + + + RV G+P
Sbjct: 555 FSKENVGQYQCFAKNDYGDAQQNIM-VDLATRPNFIQPLVNKTFSSAQPMRMDVRVDGEP 613
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASG 285
P++ W + + R+K + DG SL +++ + D G YSC A N G + S
Sbjct: 614 FPELKWMKE-WRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 672
Query: 286 YLTVY---DPPSINLSPNSVNVESGNV 309
+TV D + L V +ES V
Sbjct: 673 TVTVEAEGDYNDVELPRRRVTIESRRV 699
Score = 58.8 bits (136), Expect = 2e-08
Identities = 55/189 (29%), Positives = 85/189 (44%), Gaps = 23/189 (12%)
Query: 35 AGGSPSPAIRWYKGGVLVVS---DTHRSIL-PAGGLFFLRATHGRVHSDAGVYWCEATNS 90
A G P+P ++WYK G +V D R I G+ L + D G Y EATN
Sbjct: 140 ATGIPTPTVKWYKDGQEIVGDGPDGKRVIFTDERGIHHLVIVNAS-PDDEGEYSLEATNK 198
Query: 91 YGTARSRNA-----TLHVAVLREE--------FRLEPESKQSAQGDTVVLECLPPRGSPE 137
G+A++ + H+A E F + ++K + +CL G P
Sbjct: 199 LGSAKTEGSLNIIRPRHIADADERGGMPFPPGFVRQLKNKHVFNHMPTIFDCLVV-GHPA 257
Query: 138 PNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIAT 195
P V W NG+ ++ G ++ GG+ L+I D DAG Y A+N+ G+ S+ A
Sbjct: 258 PEVEWFHNGKKIVPGGRIKIQSCGGGSHALIILDTTLEDAGEYVATAKNSHGSASSS-AV 316
Query: 196 LKIHIKPYL 204
L + + P+L
Sbjct: 317 LDVTV-PFL 324
Score = 51.6 bits (118), Expect = 3e-06
Identities = 47/171 (27%), Positives = 75/171 (43%), Gaps = 12/171 (7%)
Query: 24 ARHQPATLNCRAGGSPSPAIRW-YKG-GVLVVSDTHR-SILPAGGLFFLRATHGRVHSDA 80
A + T+ G P P I+W ++G + S T + + GG A G +
Sbjct: 501 AENDTLTIVLNVSGFPDPDIKWKFRGWDIDTSSPTSKCKVYTYGGSETTLAITGFSKENV 560
Query: 81 GVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNV 140
G Y C A N YG A+ +N + +A R F ++P ++ + + G P P +
Sbjct: 561 GQYQCFAKNDYGDAQ-QNIMVDLAT-RPNF-IQPLVNKTFSSAQPMRMDVRVDGEPFPEL 617
Query: 141 YWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCIARNAAG 187
W K + ++ SR+ V G +L+I D D+G Y C+A N AG
Sbjct: 618 KWMKEWRPIV--ESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAG 666
Score = 46.8 bits (106), Expect = 9e-05
Identities = 29/94 (30%), Positives = 39/94 (41%), Gaps = 1/94 (1%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P + Q + V H P +C G P+P + W+ G +V I GG
Sbjct: 229 PGFVRQLKNKHVFNHMPTIFDCLVVGHPAPEVEWFHNGKKIVPGGRIKIQSCGGGSHALI 288
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAV 105
DAG Y A NS+G+A S +A L V V
Sbjct: 289 ILDTTLEDAGEYVATAKNSHGSA-SSSAVLDVTV 321
Score = 39.9 bits (89), Expect = 0.011
Identities = 21/83 (25%), Positives = 36/83 (43%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I+ ++ T + QP ++ R G P P ++W K +V + + G
Sbjct: 586 PNFIQPLVNKTFSSAQPMRMDVRVDGEPFPELKWMKEWRPIVESSRIKFVQDGPYLCSLI 645
Query: 72 THGRVHSDAGVYWCEATNSYGTA 94
+ + D+G+Y C A N G A
Sbjct: 646 INDPMWRDSGIYSCVAVNDAGQA 668
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 4/66 (6%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDG----TLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
P P + W E ++++ R DG +L++ D DSG Y+CVA + G+ S
Sbjct: 613 PFPELKWMKEWRPIVESSRIKFVQDGPYLCSLIINDPMWRDSGIYSCVAVNDAGQATTSC 672
Query: 481 ALLVDS 486
+ V++
Sbjct: 673 TVTVEA 678
>AC024817-51|AAP68914.1| 496|Caenorhabditis elegans L1 cam adhesion
molecule homologprotein 2, isoform b protein.
Length = 496
Score = 97.9 bits (233), Expect = 4e-20
Identities = 103/432 (23%), Positives = 172/432 (39%), Gaps = 51/432 (11%)
Query: 30 TLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP----AGGLFFLRATHGRVHSDAGVYWC 85
TL C A + + W K G V D+ + +G + F + H S G Y C
Sbjct: 50 TLRCEADEN-TDRYSWLKDGEPFVIDSEDVLWEKESQSGSIVFTKP-HA---SHQGYYQC 104
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW--- 142
A+N +GTA S L + L + + + + +G+++ L C PPRG+P+P + W
Sbjct: 105 FASNIFGTALSNKMHLRLGSLEHFPKRDVKLLRVKEGESLTLNCTPPRGTPDPKIVWLYR 164
Query: 143 KKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGR---YQCIARNAAGTRESAIAT-LK 197
+ +++ SR VD G+L +D Y+C A + E ++
Sbjct: 165 SLDDSSVIETIRSRHITVDNEGHLHFSSVELSDGKATLVYECAATSPVLRGEYRSGDRIQ 224
Query: 198 IHIKPY---------LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
+ I+P + P +V + G + QC GG PLP + W S G +P R
Sbjct: 225 LDIEPSQDKSHPVKKMSVSPSEVTVRAGGQLKLQCIFGGRPLPTIFW--SKIDGELPKSR 282
Query: 249 VKVL-----DDG-SLRLDNVILADEGEYSCEAENSVGAVSA---SGYLTVYDPPSINLSP 299
+K L D G SL ++NV D G Y C + V V+ + +DP P
Sbjct: 283 IKDLTSHESDFGRSLIVENVHPDDAGAYECRGRHLVHTVNVRVMAAPFWEFDP------P 336
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+++ + C A G+P P + WS+ G ++ D + D +L +
Sbjct: 337 RDISLPEESTGELECLAGGQPTPIITWSMNGK---FLHELAEDS--RRVLLDHGRILRVR 391
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPC 419
+ + + C+A N G F + V + P + + + S V C
Sbjct: 392 NLNHDLDTGVYQCNASNPLGYVFANAFVHVRA---HAPFFRMPAARHWKVVLHSTVVLDC 448
Query: 420 TAICTPEPIIAW 431
PE ++ W
Sbjct: 449 DVDAAPEAMVRW 460
Score = 70.5 bits (165), Expect = 7e-12
Identities = 93/371 (25%), Positives = 159/371 (42%), Gaps = 44/371 (11%)
Query: 142 WKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI- 198
W K+G+ + D + + + G++V + G YQC A N GT S L++
Sbjct: 64 WLKDGEPFVIDSEDVLWEKESQSGSIVFTKPHASHQGYYQCFASNIFGTALSNKMHLRLG 123
Query: 199 HIKPYLITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWR-RSAGGGNM----PLGRVKVL 252
++ + + + + G S+T C G P P ++W RS ++ + V
Sbjct: 124 SLEHFPKRDVKLLRVKEGESLTLNCTPPRGTPDPKIVWLYRSLDDSSVIETIRSRHITVD 183
Query: 253 DDGSLRLDNVILADEGE---YSCEAENSV--GAVSASGYLTVYDPPS---------INLS 298
++G L +V L+D Y C A + V G + + + PS +++S
Sbjct: 184 NEGHLHFSSVELSDGKATLVYECAATSPVLRGEYRSGDRIQLDIEPSQDKSHPVKKMSVS 243
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWS-VEGNRTIIFPGMSRDKYHATAVFDGVTVLT 357
P+ V V +G + C GRP PT+FWS ++G P SR K + D L
Sbjct: 244 PSEVTVRAGGQLKLQCIFGGRPLPTIFWSKIDGE----LP-KSRIKDLTSHESDFGRSLI 298
Query: 358 INDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+ + +D+ C + + VR + D P I +LP +S
Sbjct: 299 VENVHPDDA-GAYECRGRHLVHTVNVRVMAAPFWEFDPPRDI--------SLPEESTGEL 349
Query: 418 PCTAICTPEPIIAWYFEGE---ALIQNHRRNVTNDGTLV-LKDLDKS-DSGTYTCVASSR 472
C A P PII W G+ L ++ RR + + G ++ +++L+ D+G Y C AS+
Sbjct: 350 ECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNP 409
Query: 473 HGKYVWSGALL 483
G YV++ A +
Sbjct: 410 LG-YVFANAFV 419
Score = 56.8 bits (131), Expect = 9e-08
Identities = 42/132 (31%), Positives = 61/132 (46%), Gaps = 10/132 (7%)
Query: 16 EQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVL---VVSDTHRSILPAGGLFFLRAT 72
+ P D+++ L C AGG P+P I W G + D+ R +L G + LR
Sbjct: 334 DPPRDISLPEESTGELECLAGGQPTPIITWSMNGKFLHELAEDSRRVLLDHGRI--LRVR 391
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESK--QSAQGDTVVLECL 130
+ D GVY C A+N G + NA +HV FR+ P ++ + TVVL+C
Sbjct: 392 NLNHDLDTGVYQCNASNPLGYVFA-NAFVHVRAHAPFFRM-PAARHWKVVLHSTVVLDC- 448
Query: 131 PPRGSPEPNVYW 142
+PE V W
Sbjct: 449 DVDAAPEAMVRW 460
Score = 56.0 bits (129), Expect = 2e-07
Identities = 67/248 (27%), Positives = 93/248 (37%), Gaps = 14/248 (5%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
P +VTV L C GG P P I W K + + + F VH
Sbjct: 244 PSEVTVRAGGQLKLQCIFGGRPLPTIFWSKIDGELPKSRIKDLTSHESDFGRSLIVENVH 303
Query: 78 -SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
DAG Y C + T R +A EF P + T LECL G P
Sbjct: 304 PDDAGAYECRGRHLVHTVNVR----VMAAPFWEFD-PPRDISLPEESTGELECL-AGGQP 357
Query: 137 EPNVYWKKNGQTL-LFDGDSRMHLVDGGNLV-IQDA-RQTDAGRYQCIARNAAG-TRESA 192
P + W NG+ L DSR L+D G ++ +++ D G YQC A N G +A
Sbjct: 358 TPIITWSMNGKFLHELAEDSRRVLLDHGRILRVRNLNHDLDTGVYQCNASNPLGYVFANA 417
Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL 252
++ H + + S+V C V P V W + PL V+
Sbjct: 418 FVHVRAHAPFFRMPAARHWKVVLHSTVVLDCDVDAAPEAMVRW---VDADDRPLQVVEGK 474
Query: 253 DDGSLRLD 260
+ S ++D
Sbjct: 475 NKASTQID 482
>Z93395-7|CAH04744.1| 2389|Caenorhabditis elegans Hypothetical protein
ZC101.2f protein.
Length = 2389
Score = 91.1 bits (216), Expect = 4e-18
Identities = 128/489 (26%), Positives = 195/489 (39%), Gaps = 56/489 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G AP I P + TV + PA C G P ++W + + + IL G F
Sbjct: 1320 GAAPQI--DPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN---GILERDG--F 1372
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE-EFRLEPESKQSAQGDTVV 126
LR ++H DAG Y C +T G+ + S A L+V + + +++P + +G+
Sbjct: 1373 LRIDKSQLH-DAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQTVNEGEPSR 1431
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+ C P G P + + K G+ L +R GNL I ++D Y CIA +
Sbjct: 1432 IRCWVP-GHPNIQLQFVKRGRRPL-PAHARF---SQGNLEIPRTLKSDEDEYICIATDPT 1486
Query: 187 GTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
R ++ +K + I P + GS +C V G P + +RR +G N
Sbjct: 1487 TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVPGHPSVQLTFRRVSGQLNE 1546
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTVY-----DPPSIN-- 296
++G L + L DEG+Y C A + GA S TV+ PP +
Sbjct: 1547 DADE----NNGLLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEAR 1602
Query: 297 ------LSPNSVNVESGNVARFTCTATGRPEPTMFWSVE--GNRTIIFPGMSRDKYHATA 348
++P + + G+ AR CT G P S E + + F G S D+
Sbjct: 1603 PPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFERVDGKGLPF-GSSDDR----- 1656
Query: 349 VFDGVTVLTINDTDKNDSRNTI-VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
VLTI T D+ + + S N L VT + P P+ T P
Sbjct: 1657 -----GVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTPPRPVAT--PPLL 1709
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTY 465
++ S A F C A I W F E + H V DG +V+ + + G Y
Sbjct: 1710 SVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEH---VNQDGDDIVISEAGDRNVGEY 1766
Query: 466 TCVASSRHG 474
C A++ G
Sbjct: 1767 VCSATNDFG 1775
Score = 85.0 bits (201), Expect = 3e-16
Identities = 129/526 (24%), Positives = 193/526 (36%), Gaps = 56/526 (10%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAGG 65
G P + P + V +PA C G P I W++ GG L + G
Sbjct: 1130 GRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLP-----HGVYQTGN 1184
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
L+ ++H AG Y C A N YGT +S A L V +++P + +
Sbjct: 1185 A--LKIPQSQLHH-AGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQPA 1241
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
+C P G+ + W + G L G G L I A + G+Y C A +
Sbjct: 1242 RFKCWVP-GNSNVQLRWSRPGGAPLPSGVQEQQ----GILHIPRASDQEVGQYVCTATDP 1296
Query: 186 AGTRESAIATLKIHIK----PYLITGPE-DVVAQT---GSSVTFQCRVGGDPLPDVLWRR 237
+ ++++I+ P P+ D QT F+C V G P + W R
Sbjct: 1297 SDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWSR 1356
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--VSASGYLTVYDPPSI 295
G PL + DG LR+D L D GEY C + G+ +S L V P +I
Sbjct: 1357 KDG---RPLPNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQAI 1413
Query: 296 --NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
+ P V G +R C G P + + G R + P +R
Sbjct: 1414 QPQVDPPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPL--PAHARFSQGN------- 1464
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
L I T K+D + +C A + + V PII P+ QT+P S
Sbjct: 1465 --LEIPRTLKSD-EDEYICIATDPTTNRPVESNPARVIVKSPIRPII--DPAEQTVPEGS 1519
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
F P + F + N + N+G L ++ + +D G Y C A
Sbjct: 1520 --PFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-ENNGLLAVQRAELTDEGDYICTARDPD 1576
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPG-PPTKPITHNVTDT 518
+GA + +P +H AA + PP P+ T T
Sbjct: 1577 -----TGAPIDSTP--ATVHVTNAAAPPQVEARPPQHPVITPQTQT 1615
Score = 71.7 bits (168), Expect = 3e-12
Identities = 112/483 (23%), Positives = 181/483 (37%), Gaps = 52/483 (10%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
++ P+ TV +P+ + C G P+ +++ K G + R G L R
Sbjct: 1417 VDPPVQ-TVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRT--- 1470
Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVVLECLPP 132
+ SD Y C AT+ T R + +++ R ++P + +G + C P
Sbjct: 1471 -LKSDEDEYICIATDPT-TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVP 1528
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN--AAGTRE 190
G P + +++ L D D + G L +Q A TD G Y C AR+ +
Sbjct: 1529 -GHPSVQLTFRRVSGQLNEDADE-----NNGLLAVQRAELTDEGDYICTARDPDTGAPID 1582
Query: 191 SAIATL---------KIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRR 237
S AT+ ++ +P + + P+ G QC V G+P + + R
Sbjct: 1583 STPATVHVTNAAAPPQVEARPPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFER 1642
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC--EAENSVGAVSASGYLTVYD---P 292
G G +P G D G L + + L D GEY C ENS + L V P
Sbjct: 1643 VDGKG-LPFGSSD--DRGVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTP 1699
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P +P ++V G+ ARF C A + W + +++D D
Sbjct: 1700 PRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVNQDG-------DD 1752
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
+ + D + + VCSA N G+ V + + +D+ PP P
Sbjct: 1753 IVISEAGDRNVGE----YVCSATNDFGTG-VADPVRLEVTEDQEPPTAVVEPRTWNGKPG 1807
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
F C +P P I W + + H L + +G YTC AS+
Sbjct: 1808 ERHQFRCITTGSPTPKITWTGPNGSPLP-HDVTPLEPNILDFSNGRSELNGDYTCTASNP 1866
Query: 473 HGK 475
G+
Sbjct: 1867 IGE 1869
Score = 70.1 bits (164), Expect = 9e-12
Identities = 86/328 (26%), Positives = 129/328 (39%), Gaps = 32/328 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + P ++VA PA NC A IRW G + + G
Sbjct: 1697 GTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRW---GFREENGPLPEHVNQDGDDI 1753
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVV 126
+ + G + G Y C ATN +GT + L V +E +EP + G+
Sbjct: 1754 VISEAG--DRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQ 1811
Query: 127 LECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
C+ GSP P + W NG L D + ++ L + R G Y C A N
Sbjct: 1812 FRCITT-GSPTPKITWTGPNGSPLPHD----VTPLEPNILDFSNGRSELNGDYTCTASNP 1866
Query: 186 AGTRESAIATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRR 237
G A ++I P L GP+ +V G + +C GDP P+V W
Sbjct: 1867 IG---EASDHGNVNIGPSLTVKTNPPGPKLIVT-VGEPLQVKCEAFGAPGDPEPEVEWLH 1922
Query: 238 SAGG--GNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
G G++P V + + +R NV L + G Y+C+ ++ + + Y+ V +P
Sbjct: 1923 DPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHATATKNIYIEVVEPSR 1982
Query: 295 IN----LSPNSVNVESGNVARFTCTATG 318
I L +S + G CTATG
Sbjct: 1983 IATVSILGGSSQWFDQGEKGELICTATG 2010
Score = 62.9 bits (146), Expect = 1e-09
Identities = 123/478 (25%), Positives = 185/478 (38%), Gaps = 58/478 (12%)
Query: 19 LDVTVARHQPATLNCRAGGSPS---PAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHG 74
L VTV +P + C A G+P P + W D P F+R H
Sbjct: 1893 LIVTVG--EPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIR--HP 1948
Query: 75 RVH-SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECL 130
V +AGVY C+ ++++ TA ++N + V + L S+ QG+ L C
Sbjct: 1949 NVGLGNAGVYTCKGSSAHATA-TKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICT 2007
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--------IA 182
S + W+K L D + + G L + + AG Y+C IA
Sbjct: 2008 ATGSSLVDRLEWEKVDDQLPTDVEEHN---EPGLLHFPSFKNSYAGEYRCNGYRNNEIIA 2064
Query: 183 RNAAGTRESAIAT--LKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239
A SA A K+ I+P P V G ++ +C V G + W
Sbjct: 2065 SAAVHVHSSANADDEPKVEIEP-----PRVRVVSQGDNIVLKCSVQGAENGEHFKWALLR 2119
Query: 240 GGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
GG + LG L+ N D G Y C E++ G V S + V
Sbjct: 2120 GGSLVRQLGTEPTLEITKADPSN----DFGVYRCNVEDNNGLVIGSAFTAVSVGQQDKSH 2175
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V + + A FTC P + W+ E P + AV +G + I
Sbjct: 2176 AQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGD---LP--------SKAVPNG-NKIEI 2223
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAV 416
+ D + S T VC V++ G+ V G VT+ P II S+++ I A
Sbjct: 2224 KEFD-DASAGTYVCK-VSFDGN-VVEG--FVTAQMFVPDTIIQVLLEVSSESPQIGDRAW 2278
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
F C P +I+W EG + + + VT G L+ DL + ++G Y CVA ++ G
Sbjct: 2279 FDCKVTGDPSAVISWTKEGNDDLPPNAQ-VTG-GRLLFTDLKEDNAGVYRCVAKTKAG 2334
Score = 60.1 bits (139), Expect = 9e-09
Identities = 47/175 (26%), Positives = 70/175 (40%), Gaps = 12/175 (6%)
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGS 217
DG ++VI +A + G Y C A N GT + L++ P + P + G
Sbjct: 1749 DGDDIVISEAGDRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGE 1808
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAEN 276
F+C G P P + W G PL V L+ L N G+Y+C A N
Sbjct: 1809 RHQFRCITTGSPTPKITW---TGPNGSPLPHDVTPLEPNILDFSNGRSELNGDYTCTASN 1865
Query: 277 SVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTCT---ATGRPEPTMFW 326
+G S G + + ++ +P + V G + C A G PEP + W
Sbjct: 1866 PIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 1920
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 12/135 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLV 453
P ++ +N +P + C A+ PEP I W + + R T++ GTL
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGTLT 330
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ D D G YTC A + G+ + + +V +P P PPT P
Sbjct: 331 IHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPR---------PQPPQPPTAPPQR 381
Query: 514 NVTDTSVTLSWSQNN 528
DT ++ NN
Sbjct: 382 ASCDTRGAVTPYPNN 396
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 267 EGEYSC-EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+G C + + VG V TV DPP NL V G TC A PEP +
Sbjct: 254 DGTNDCHDGSDEVGCVQP----TVVDPPQTNLQ-----VPRGTTFSLTCKAVAVPEPYIN 304
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W + P + T+ G LTI+D D + C A+N G
Sbjct: 305 WRLNWG-----PVCEPPRCLQTSE-GGYGTLTIHDAQPVD-QGAYTCEAINVKGRVLATP 357
Query: 386 KLTV-TSDDDRPPP 398
V DD RP P
Sbjct: 358 DCIVRVVDDPRPQP 371
Score = 36.7 bits (81), Expect = 0.10
Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 8/142 (5%)
Query: 152 DGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
+GD V GN + I++ AG Y C + G T ++ + +I +
Sbjct: 2207 NGDLPSKAVPNGNKIEIKEFDDASAGTYVCKV-SFDGNVVEGFVTAQMFVPDTIIQVLLE 2265
Query: 211 VVA---QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
V + Q G F C+V GDP + W + GN L + G L ++ +
Sbjct: 2266 VSSESPQIGDRAWFDCKVTGDPSAVISWTKE---GNDDLPPNAQVTGGRLLFTDLKEDNA 2322
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A+ G + L V
Sbjct: 2323 GVYRCVAKTKAGPLQTRTVLNV 2344
Score = 35.5 bits (78), Expect = 0.23
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 208 PEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P + + G V+F+CR P V W R G PL G L ++ V L
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGG----PLPSSAHDSGGRLTINPVQL 106
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV--YDPPSIN 296
+D G Y C ++ + V A L+V Y P ++
Sbjct: 107 SDAGTYICVSDYNGNTVEARATLSVVSYGPQEVS 140
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 200 IKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
++P ++ P+ ++ G++ + C+ P P + WR + G P ++ + G +
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT 328
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSAS 284
L + + D+G Y+CEA N G V A+
Sbjct: 329 LTIHDAQPVDQGAYTCEAINVKGRVLAT 356
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 12 PYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P +++ P ++ V R +L C+A P P I W + V + R + + G +
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINW-RLNWGPVCEPPRCLQTSEGGYGTL 329
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
H D G Y CEA N G
Sbjct: 330 TIHDAQPVDQGAYTCEAINVKG 351
Score = 33.1 bits (72), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 114 PESKQSAQGDTVVLECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
P K+ G V EC S P V W + G L S H GG L I +
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL----PSSAH-DSGGRLTINPVQ 105
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI 198
+DAG Y C++ T E A ATL +
Sbjct: 106 LSDAGTYICVSDYNGNTVE-ARATLSV 131
Score = 32.3 bits (70), Expect = 2.2
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDA 175
Q +G T L C PEP + W+ N + + + +GG L I DA+ D
Sbjct: 282 QVPRGTTFSLTCKAV-AVPEPYINWRLNWGPVC-EPPRCLQTSEGGYGTLTIHDAQPVDQ 339
Query: 176 GRYQCIARNAAG 187
G Y C A N G
Sbjct: 340 GAYTCEAINVKG 351
>Z93395-6|CAB07708.1| 3375|Caenorhabditis elegans Hypothetical protein
ZC101.2e protein.
Length = 3375
Score = 91.1 bits (216), Expect = 4e-18
Identities = 128/489 (26%), Positives = 195/489 (39%), Gaps = 56/489 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G AP I P + TV + PA C G P ++W + + + IL G F
Sbjct: 1413 GAAPQI--DPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN---GILERDG--F 1465
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE-EFRLEPESKQSAQGDTVV 126
LR ++H DAG Y C +T G+ + S A L+V + + +++P + +G+
Sbjct: 1466 LRIDKSQLH-DAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQTVNEGEPSR 1524
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+ C P G P + + K G+ L +R GNL I ++D Y CIA +
Sbjct: 1525 IRCWVP-GHPNIQLQFVKRGRRPL-PAHARF---SQGNLEIPRTLKSDEDEYICIATDPT 1579
Query: 187 GTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
R ++ +K + I P + GS +C V G P + +RR +G N
Sbjct: 1580 TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVPGHPSVQLTFRRVSGQLNE 1639
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTVY-----DPPSIN-- 296
++G L + L DEG+Y C A + GA S TV+ PP +
Sbjct: 1640 DADE----NNGLLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEAR 1695
Query: 297 ------LSPNSVNVESGNVARFTCTATGRPEPTMFWSVE--GNRTIIFPGMSRDKYHATA 348
++P + + G+ AR CT G P S E + + F G S D+
Sbjct: 1696 PPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFERVDGKGLPF-GSSDDR----- 1749
Query: 349 VFDGVTVLTINDTDKNDSRNTI-VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
VLTI T D+ + + S N L VT + P P+ T P
Sbjct: 1750 -----GVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTPPRPVAT--PPLL 1802
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTY 465
++ S A F C A I W F E + H V DG +V+ + + G Y
Sbjct: 1803 SVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEH---VNQDGDDIVISEAGDRNVGEY 1859
Query: 466 TCVASSRHG 474
C A++ G
Sbjct: 1860 VCSATNDFG 1868
Score = 86.6 bits (205), Expect = 9e-17
Identities = 130/527 (24%), Positives = 194/527 (36%), Gaps = 56/527 (10%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAG 64
SG P + P + V +PA C G P I W++ GG L + G
Sbjct: 1222 SGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLP-----HGVYQTG 1276
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L+ ++H AG Y C A N YGT +S A L V +++P + +
Sbjct: 1277 NA--LKIPQSQLHH-AGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQP 1333
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+C P G+ + W + G L G G L I A + G+Y C A +
Sbjct: 1334 ARFKCWVP-GNSNVQLRWSRPGGAPLPSGVQEQQ----GILHIPRASDQEVGQYVCTATD 1388
Query: 185 AAGTRESAIATLKIHIK----PYLITGPE-DVVAQT---GSSVTFQCRVGGDPLPDVLWR 236
+ ++++I+ P P+ D QT F+C V G P + W
Sbjct: 1389 PSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWS 1448
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--VSASGYLTVYDPPS 294
R G PL + DG LR+D L D GEY C + G+ +S L V P +
Sbjct: 1449 RKDG---RPLPNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQA 1505
Query: 295 I--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I + P V G +R C G P + + G R + P +R
Sbjct: 1506 IQPQVDPPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPL--PAHARFSQGN------ 1557
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I T K+D + +C A + + V PII P+ QT+P
Sbjct: 1558 ---LEIPRTLKSD-EDEYICIATDPTTNRPVESNPARVIVKSPIRPII--DPAEQTVPEG 1611
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
S F P + F + N + N+G L ++ + +D G Y C A
Sbjct: 1612 S--PFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-ENNGLLAVQRAELTDEGDYICTARDP 1668
Query: 473 HGKYVWSGALLVDSPINPNIHFFRAADVSSLPG-PPTKPITHNVTDT 518
+GA + +P +H AA + PP P+ T T
Sbjct: 1669 D-----TGAPIDSTP--ATVHVTNAAAPPQVEARPPQHPVITPQTQT 1708
Score = 71.7 bits (168), Expect = 3e-12
Identities = 85/374 (22%), Positives = 142/374 (37%), Gaps = 31/374 (8%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170
+EP+ + + GD V C + E +V W K G+ L +++ + G LV++
Sbjct: 1135 MEPKRQIALPGDRVHWICQVTGYTTEKIHVEWTKVGEMSL-PPNAKAY---DGYLVLKGV 1190
Query: 171 RQTDAGRYQCIARNAAG-TRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVG 226
+AG+Y+C A + A+ T+ I P + P +V G F+C V
Sbjct: 1191 EAENAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP 1250
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
G P + W R GG +P G + +L++ L G Y C A N G +
Sbjct: 1251 GIPDCQITWHREQLGGPLPHGVYQT--GNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 287 LTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
+ P I + P V+ ARF C G + WS G +
Sbjct: 1309 VLEVKKPVIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRPGGAPL---------- 1358
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----II 400
+ V + +L I + VC+A + + ++ ++ + + D PP
Sbjct: 1359 -PSGVQEQQGILHIPRASDQEV-GQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAP 1416
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
P NQT+ + A F C P + W + + N + DG L +
Sbjct: 1417 QIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN--GILERDGFLRIDKSQLH 1474
Query: 461 DSGTYTCVASSRHG 474
D+G Y C ++ G
Sbjct: 1475 DAGEYECTSTEPDG 1488
Score = 71.7 bits (168), Expect = 3e-12
Identities = 112/483 (23%), Positives = 181/483 (37%), Gaps = 52/483 (10%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
++ P+ TV +P+ + C G P+ +++ K G + R G L R
Sbjct: 1510 VDPPVQ-TVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRT--- 1563
Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVVLECLPP 132
+ SD Y C AT+ T R + +++ R ++P + +G + C P
Sbjct: 1564 -LKSDEDEYICIATDPT-TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVP 1621
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN--AAGTRE 190
G P + +++ L D D + G L +Q A TD G Y C AR+ +
Sbjct: 1622 -GHPSVQLTFRRVSGQLNEDADE-----NNGLLAVQRAELTDEGDYICTARDPDTGAPID 1675
Query: 191 SAIATL---------KIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRR 237
S AT+ ++ +P + + P+ G QC V G+P + + R
Sbjct: 1676 STPATVHVTNAAAPPQVEARPPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFER 1735
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC--EAENSVGAVSASGYLTVYD---P 292
G G +P G D G L + + L D GEY C ENS + L V P
Sbjct: 1736 VDGKG-LPFGSSD--DRGVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTP 1792
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P +P ++V G+ ARF C A + W + +++D D
Sbjct: 1793 PRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVNQDG-------DD 1845
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
+ + D + + VCSA N G+ V + + +D+ PP P
Sbjct: 1846 IVISEAGDRNVGE----YVCSATNDFGTG-VADPVRLEVTEDQEPPTAVVEPRTWNGKPG 1900
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
F C +P P I W + + H L + +G YTC AS+
Sbjct: 1901 ERHQFRCITTGSPTPKITWTGPNGSPLP-HDVTPLEPNILDFSNGRSELNGDYTCTASNP 1959
Query: 473 HGK 475
G+
Sbjct: 1960 IGE 1962
Score = 70.1 bits (164), Expect = 9e-12
Identities = 86/328 (26%), Positives = 129/328 (39%), Gaps = 32/328 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + P ++VA PA NC A IRW G + + G
Sbjct: 1790 GTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRW---GFREENGPLPEHVNQDGDDI 1846
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVV 126
+ + G + G Y C ATN +GT + L V +E +EP + G+
Sbjct: 1847 VISEAG--DRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQ 1904
Query: 127 LECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
C+ GSP P + W NG L D + ++ L + R G Y C A N
Sbjct: 1905 FRCITT-GSPTPKITWTGPNGSPLPHD----VTPLEPNILDFSNGRSELNGDYTCTASNP 1959
Query: 186 AGTRESAIATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRR 237
G A ++I P L GP+ +V G + +C GDP P+V W
Sbjct: 1960 IG---EASDHGNVNIGPSLTVKTNPPGPKLIVT-VGEPLQVKCEAFGAPGDPEPEVEWLH 2015
Query: 238 SAGG--GNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
G G++P V + + +R NV L + G Y+C+ ++ + + Y+ V +P
Sbjct: 2016 DPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHATATKNIYIEVVEPSR 2075
Query: 295 IN----LSPNSVNVESGNVARFTCTATG 318
I L +S + G CTATG
Sbjct: 2076 IATVSILGGSSQWFDQGEKGELICTATG 2103
Score = 62.9 bits (146), Expect = 1e-09
Identities = 123/478 (25%), Positives = 185/478 (38%), Gaps = 58/478 (12%)
Query: 19 LDVTVARHQPATLNCRAGGSPS---PAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHG 74
L VTV +P + C A G+P P + W D P F+R H
Sbjct: 1986 LIVTVG--EPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIR--HP 2041
Query: 75 RVH-SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECL 130
V +AGVY C+ ++++ TA ++N + V + L S+ QG+ L C
Sbjct: 2042 NVGLGNAGVYTCKGSSAHATA-TKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICT 2100
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--------IA 182
S + W+K L D + + G L + + AG Y+C IA
Sbjct: 2101 ATGSSLVDRLEWEKVDDQLPTDVEEHN---EPGLLHFPSFKNSYAGEYRCNGYRNNEIIA 2157
Query: 183 RNAAGTRESAIAT--LKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239
A SA A K+ I+P P V G ++ +C V G + W
Sbjct: 2158 SAAVHVHSSANADDEPKVEIEP-----PRVRVVSQGDNIVLKCSVQGAENGEHFKWALLR 2212
Query: 240 GGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
GG + LG L+ N D G Y C E++ G V S + V
Sbjct: 2213 GGSLVRQLGTEPTLEITKADPSN----DFGVYRCNVEDNNGLVIGSAFTAVSVGQQDKSH 2268
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V + + A FTC P + W+ E P + AV +G + I
Sbjct: 2269 AQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGD---LP--------SKAVPNG-NKIEI 2316
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAV 416
+ D + S T VC V++ G+ V G VT+ P II S+++ I A
Sbjct: 2317 KEFD-DASAGTYVCK-VSFDGN-VVEG--FVTAQMFVPDTIIQVLLEVSSESPQIGDRAW 2371
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
F C P +I+W EG + + + VT G L+ DL + ++G Y CVA ++ G
Sbjct: 2372 FDCKVTGDPSAVISWTKEGNDDLPPNAQ-VTG-GRLLFTDLKEDNAGVYRCVAKTKAG 2427
Score = 60.5 bits (140), Expect = 7e-09
Identities = 103/435 (23%), Positives = 168/435 (38%), Gaps = 48/435 (11%)
Query: 79 DAGVYWCEATN--SYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+AG Y C AT Y T + + ++ + ++P +G+ C P G
Sbjct: 1194 NAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP-GI 1252
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
P+ + W + G + GN L I ++ AGRY C A N GT +S A
Sbjct: 1253 PDCQITWHREQ----LGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 195 TLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
L++ KP +I D + QT F+C V G+ + W R GG +P G +
Sbjct: 1309 VLEVK-KP-VIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRP-GGAPLPSGVQE- 1364
Query: 252 LDDGSLRLDNVILADEGEYSCEA---ENSVGAVSASGYLTVYDPP------SINLSPNSV 302
G L + + G+Y C A ++ S L + DP + + P +
Sbjct: 1365 -QQGILHIPRASDQEVGQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQ 1423
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V + A+F C G+P + WS + R + + RD + L I+ +
Sbjct: 1424 TVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPNGILERDGF-----------LRIDKSQ 1472
Query: 363 KNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
+D+ C++ GS+ + +L V P + P QT+ + C
Sbjct: 1473 LHDA-GEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQV---DPPVQTVNEGEPSRIRCW 1528
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS-RHGKYVWS 479
P + + G + H R + G L + KSD Y C+A+ + V S
Sbjct: 1529 VPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRTLKSDEDEYICIATDPTTNRPVES 1586
Query: 480 --GALLVDSPINPNI 492
++V SPI P I
Sbjct: 1587 NPARVIVKSPIRPII 1601
Score = 60.1 bits (139), Expect = 9e-09
Identities = 47/175 (26%), Positives = 70/175 (40%), Gaps = 12/175 (6%)
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGS 217
DG ++VI +A + G Y C A N GT + L++ P + P + G
Sbjct: 1842 DGDDIVISEAGDRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGE 1901
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAEN 276
F+C G P P + W G PL V L+ L N G+Y+C A N
Sbjct: 1902 RHQFRCITTGSPTPKITW---TGPNGSPLPHDVTPLEPNILDFSNGRSELNGDYTCTASN 1958
Query: 277 SVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTCT---ATGRPEPTMFW 326
+G S G + + ++ +P + V G + C A G PEP + W
Sbjct: 1959 PIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 2013
Score = 57.2 bits (132), Expect = 7e-08
Identities = 71/292 (24%), Positives = 113/292 (38%), Gaps = 23/292 (7%)
Query: 78 SDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
+ AG Y C+ + A + V + LE S+ GD +C G P
Sbjct: 2322 ASAGTYVCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDC-KVTGDP 2380
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA---- 192
+ W K G L V GG L+ D ++ +AG Y+C+A+ AG ++
Sbjct: 2381 SAVISWTKEGNDDLPPNAQ----VTGGRLLFTDLKEDNAGVYRCVAKTKAGPLQTRTVLN 2436
Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQC--RVGGDPLPDVLWRRSAGGGNMPLGRVK 250
+ + K + + VV G C + P V+W + G++P G
Sbjct: 2437 VGSGKQDQVTFTVADSLPVVYTVGQPAYLSCIGKTETKPNQSVVWTKEE--GDLPSG--S 2492
Query: 251 VLDDGSLRLDNVILADEGEYSCE---AENSVGA---VSASGYLTVYDPPSINLSPNSVNV 304
++ G L L +V DEG Y+CE EN V + + ++ V D I L P S +
Sbjct: 2493 RVEQGVLMLPSVHRDDEGSYTCEIVKEENPVFSTVDLQIDDFIPVIDGEPIELPPLS-DE 2551
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
E N+ T P+ +F + N + +H + D TVL
Sbjct: 2552 EIVNLDIEITLNTANPKGIIFETKRINSGDLLATPYDTIHHEAKITDYGTVL 2603
Score = 46.0 bits (104), Expect = 2e-04
Identities = 90/401 (22%), Positives = 136/401 (33%), Gaps = 35/401 (8%)
Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLE---PESKQSAQGDTVVLECLPP 132
+S AG Y C + S +H + +E ++E P + +QGD +VL+C
Sbjct: 2139 NSYAGEYRCNGYRNNEIIASAAVHVHSSANADDEPKVEIEPPRVRVVSQGDNIVLKCSVQ 2198
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIARNAAGTRES 191
+ W LL G L L I A D G Y+C + G
Sbjct: 2199 GAENGEHFKW-----ALLRGGSLVRQLGTEPTLEITKADPSNDFGVYRCNVEDNNGLVIG 2253
Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
+ T + + + + V S +F C + P V W + G++P V
Sbjct: 2254 SAFT-AVSVGQQDKSHAQIVKFDDKSDASFTCPIYSVPGSKVDW--TYENGDLPSKAVP- 2309
Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGN 308
+ + + A G Y C+ V ++ P +I L +S + + G+
Sbjct: 2310 -NGNKIEIKEFDDASAGTYVCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGD 2368
Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
A F C TG P + W+ EGN D A G +L D K D+
Sbjct: 2369 RAWFDCKVTGDPSAVISWTKEGN----------DDLPPNAQVTGGRLL-FTDL-KEDNAG 2416
Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP- 427
C A AG R L V S + A C +P
Sbjct: 2417 VYRCVAKTKAGPLQTRTVLNVGSGKQDQVTFTVADSLPVVYTVGQPAYLSCIGKTETKPN 2476
Query: 428 -IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
+ W E L R G L+L + + D G+YTC
Sbjct: 2477 QSVVWTKEEGDLPSGSR---VEQGVLMLPSVHRDDEGSYTC 2514
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 12/135 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLV 453
P ++ +N +P + C A+ PEP I W + + R T++ GTL
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGTLT 330
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ D D G YTC A + G+ + + +V +P P PPT P
Sbjct: 331 IHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPR---------PQPPQPPTAPPQR 381
Query: 514 NVTDTSVTLSWSQNN 528
DT ++ NN
Sbjct: 382 ASCDTRGAVTPYPNN 396
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 267 EGEYSC-EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+G C + + VG V TV DPP NL V G TC A PEP +
Sbjct: 254 DGTNDCHDGSDEVGCVQP----TVVDPPQTNLQ-----VPRGTTFSLTCKAVAVPEPYIN 304
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W + P + T+ G LTI+D D + C A+N G
Sbjct: 305 WRLNWG-----PVCEPPRCLQTSE-GGYGTLTIHDAQPVD-QGAYTCEAINVKGRVLATP 357
Query: 386 KLTV-TSDDDRPPP 398
V DD RP P
Sbjct: 358 DCIVRVVDDPRPQP 371
Score = 35.5 bits (78), Expect = 0.23
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 208 PEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P + + G V+F+CR P V W R G PL G L ++ V L
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGG----PLPSSAHDSGGRLTINPVQL 106
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV--YDPPSIN 296
+D G Y C ++ + V A L+V Y P ++
Sbjct: 107 SDAGTYICVSDYNGNTVEARATLSVVSYGPQEVS 140
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 200 IKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
++P ++ P+ ++ G++ + C+ P P + WR + G P ++ + G +
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT 328
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSAS 284
L + + D+G Y+CEA N G V A+
Sbjct: 329 LTIHDAQPVDQGAYTCEAINVKGRVLAT 356
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 12 PYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P +++ P ++ V R +L C+A P P I W + V + R + + G +
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINW-RLNWGPVCEPPRCLQTSEGGYGTL 329
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
H D G Y CEA N G
Sbjct: 330 TIHDAQPVDQGAYTCEAINVKG 351
Score = 33.1 bits (72), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 114 PESKQSAQGDTVVLECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
P K+ G V EC S P V W + G L S H GG L I +
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL----PSSAH-DSGGRLTINPVQ 105
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI 198
+DAG Y C++ T E A ATL +
Sbjct: 106 LSDAGTYICVSDYNGNTVE-ARATLSV 131
Score = 32.3 bits (70), Expect = 2.2
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDA 175
Q +G T L C PEP + W+ N + + + +GG L I DA+ D
Sbjct: 282 QVPRGTTFSLTCKAV-AVPEPYINWRLNWGPVC-EPPRCLQTSEGGYGTLTIHDAQPVDQ 339
Query: 176 GRYQCIARNAAG 187
G Y C A N G
Sbjct: 340 GAYTCEAINVKG 351
Score = 31.5 bits (68), Expect = 3.8
Identities = 40/157 (25%), Positives = 58/157 (36%), Gaps = 17/157 (10%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A +C+ G PS I W K G D + GG +AGVY C A
Sbjct: 2370 AWFDCKVTGDPSAVISWTKEG---NDDLPPNAQVTGGRLLFTDLK---EDNAGVYRCVAK 2423
Query: 89 NSYGTARSRNATLHVAVLREE---FRL-EPESKQSAQGDTVVLECL-PPRGSPEPNVYWK 143
G ++R L+V +++ F + + G L C+ P +V W
Sbjct: 2424 TKAGPLQTR-TVLNVGSGKQDQVTFTVADSLPVVYTVGQPAYLSCIGKTETKPNQSVVWT 2482
Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
K L SR V+ G L++ + D G Y C
Sbjct: 2483 KEEGDL--PSGSR---VEQGVLMLPSVHRDDEGSYTC 2514
>Z93395-3|CAB07706.1| 2482|Caenorhabditis elegans Hypothetical protein
ZC101.2a protein.
Length = 2482
Score = 91.1 bits (216), Expect = 4e-18
Identities = 128/489 (26%), Positives = 195/489 (39%), Gaps = 56/489 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G AP I P + TV + PA C G P ++W + + + IL G F
Sbjct: 1413 GAAPQI--DPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN---GILERDG--F 1465
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE-EFRLEPESKQSAQGDTVV 126
LR ++H DAG Y C +T G+ + S A L+V + + +++P + +G+
Sbjct: 1466 LRIDKSQLH-DAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQTVNEGEPSR 1524
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+ C P G P + + K G+ L +R GNL I ++D Y CIA +
Sbjct: 1525 IRCWVP-GHPNIQLQFVKRGRRPL-PAHARF---SQGNLEIPRTLKSDEDEYICIATDPT 1579
Query: 187 GTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
R ++ +K + I P + GS +C V G P + +RR +G N
Sbjct: 1580 TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVPGHPSVQLTFRRVSGQLNE 1639
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTVY-----DPPSIN-- 296
++G L + L DEG+Y C A + GA S TV+ PP +
Sbjct: 1640 DADE----NNGLLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEAR 1695
Query: 297 ------LSPNSVNVESGNVARFTCTATGRPEPTMFWSVE--GNRTIIFPGMSRDKYHATA 348
++P + + G+ AR CT G P S E + + F G S D+
Sbjct: 1696 PPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFERVDGKGLPF-GSSDDR----- 1749
Query: 349 VFDGVTVLTINDTDKNDSRNTI-VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
VLTI T D+ + + S N L VT + P P+ T P
Sbjct: 1750 -----GVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTPPRPVAT--PPLL 1802
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTY 465
++ S A F C A I W F E + H V DG +V+ + + G Y
Sbjct: 1803 SVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEH---VNQDGDDIVISEAGDRNVGEY 1859
Query: 466 TCVASSRHG 474
C A++ G
Sbjct: 1860 VCSATNDFG 1868
Score = 86.6 bits (205), Expect = 9e-17
Identities = 130/527 (24%), Positives = 194/527 (36%), Gaps = 56/527 (10%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAG 64
SG P + P + V +PA C G P I W++ GG L + G
Sbjct: 1222 SGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLP-----HGVYQTG 1276
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L+ ++H AG Y C A N YGT +S A L V +++P + +
Sbjct: 1277 NA--LKIPQSQLHH-AGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQP 1333
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+C P G+ + W + G L G G L I A + G+Y C A +
Sbjct: 1334 ARFKCWVP-GNSNVQLRWSRPGGAPLPSGVQEQQ----GILHIPRASDQEVGQYVCTATD 1388
Query: 185 AAGTRESAIATLKIHIK----PYLITGPE-DVVAQT---GSSVTFQCRVGGDPLPDVLWR 236
+ ++++I+ P P+ D QT F+C V G P + W
Sbjct: 1389 PSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWS 1448
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--VSASGYLTVYDPPS 294
R G PL + DG LR+D L D GEY C + G+ +S L V P +
Sbjct: 1449 RKDG---RPLPNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQA 1505
Query: 295 I--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I + P V G +R C G P + + G R + P +R
Sbjct: 1506 IQPQVDPPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPL--PAHARFSQGN------ 1557
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I T K+D + +C A + + V PII P+ QT+P
Sbjct: 1558 ---LEIPRTLKSD-EDEYICIATDPTTNRPVESNPARVIVKSPIRPII--DPAEQTVPEG 1611
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
S F P + F + N + N+G L ++ + +D G Y C A
Sbjct: 1612 S--PFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-ENNGLLAVQRAELTDEGDYICTARDP 1668
Query: 473 HGKYVWSGALLVDSPINPNIHFFRAADVSSLPG-PPTKPITHNVTDT 518
+GA + +P +H AA + PP P+ T T
Sbjct: 1669 D-----TGAPIDSTP--ATVHVTNAAAPPQVEARPPQHPVITPQTQT 1708
Score = 71.7 bits (168), Expect = 3e-12
Identities = 85/374 (22%), Positives = 142/374 (37%), Gaps = 31/374 (8%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170
+EP+ + + GD V C + E +V W K G+ L +++ + G LV++
Sbjct: 1135 MEPKRQIALPGDRVHWICQVTGYTTEKIHVEWTKVGEMSL-PPNAKAY---DGYLVLKGV 1190
Query: 171 RQTDAGRYQCIARNAAG-TRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVG 226
+AG+Y+C A + A+ T+ I P + P +V G F+C V
Sbjct: 1191 EAENAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP 1250
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
G P + W R GG +P G + +L++ L G Y C A N G +
Sbjct: 1251 GIPDCQITWHREQLGGPLPHGVYQT--GNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 287 LTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
+ P I + P V+ ARF C G + WS G +
Sbjct: 1309 VLEVKKPVIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRPGGAPL---------- 1358
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----II 400
+ V + +L I + VC+A + + ++ ++ + + D PP
Sbjct: 1359 -PSGVQEQQGILHIPRASDQEV-GQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAP 1416
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
P NQT+ + A F C P + W + + N + DG L +
Sbjct: 1417 QIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN--GILERDGFLRIDKSQLH 1474
Query: 461 DSGTYTCVASSRHG 474
D+G Y C ++ G
Sbjct: 1475 DAGEYECTSTEPDG 1488
Score = 71.7 bits (168), Expect = 3e-12
Identities = 112/483 (23%), Positives = 181/483 (37%), Gaps = 52/483 (10%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
++ P+ TV +P+ + C G P+ +++ K G + R G L R
Sbjct: 1510 VDPPVQ-TVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRT--- 1563
Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVVLECLPP 132
+ SD Y C AT+ T R + +++ R ++P + +G + C P
Sbjct: 1564 -LKSDEDEYICIATDPT-TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVP 1621
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN--AAGTRE 190
G P + +++ L D D + G L +Q A TD G Y C AR+ +
Sbjct: 1622 -GHPSVQLTFRRVSGQLNEDADE-----NNGLLAVQRAELTDEGDYICTARDPDTGAPID 1675
Query: 191 SAIATL---------KIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRR 237
S AT+ ++ +P + + P+ G QC V G+P + + R
Sbjct: 1676 STPATVHVTNAAAPPQVEARPPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFER 1735
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC--EAENSVGAVSASGYLTVYD---P 292
G G +P G D G L + + L D GEY C ENS + L V P
Sbjct: 1736 VDGKG-LPFGSSD--DRGVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTP 1792
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P +P ++V G+ ARF C A + W + +++D D
Sbjct: 1793 PRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVNQDG-------DD 1845
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
+ + D + + VCSA N G+ V + + +D+ PP P
Sbjct: 1846 IVISEAGDRNVGE----YVCSATNDFGTG-VADPVRLEVTEDQEPPTAVVEPRTWNGKPG 1900
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
F C +P P I W + + H L + +G YTC AS+
Sbjct: 1901 ERHQFRCITTGSPTPKITWTGPNGSPLP-HDVTPLEPNILDFSNGRSELNGDYTCTASNP 1959
Query: 473 HGK 475
G+
Sbjct: 1960 IGE 1962
Score = 70.1 bits (164), Expect = 9e-12
Identities = 86/328 (26%), Positives = 129/328 (39%), Gaps = 32/328 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + P ++VA PA NC A IRW G + + G
Sbjct: 1790 GTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRW---GFREENGPLPEHVNQDGDDI 1846
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVV 126
+ + G + G Y C ATN +GT + L V +E +EP + G+
Sbjct: 1847 VISEAG--DRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQ 1904
Query: 127 LECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
C+ GSP P + W NG L D + ++ L + R G Y C A N
Sbjct: 1905 FRCITT-GSPTPKITWTGPNGSPLPHD----VTPLEPNILDFSNGRSELNGDYTCTASNP 1959
Query: 186 AGTRESAIATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRR 237
G A ++I P L GP+ +V G + +C GDP P+V W
Sbjct: 1960 IG---EASDHGNVNIGPSLTVKTNPPGPKLIVT-VGEPLQVKCEAFGAPGDPEPEVEWLH 2015
Query: 238 SAGG--GNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
G G++P V + + +R NV L + G Y+C+ ++ + + Y+ V +P
Sbjct: 2016 DPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHATATKNIYIEVVEPSR 2075
Query: 295 IN----LSPNSVNVESGNVARFTCTATG 318
I L +S + G CTATG
Sbjct: 2076 IATVSILGGSSQWFDQGEKGELICTATG 2103
Score = 62.9 bits (146), Expect = 1e-09
Identities = 123/478 (25%), Positives = 185/478 (38%), Gaps = 58/478 (12%)
Query: 19 LDVTVARHQPATLNCRAGGSPS---PAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHG 74
L VTV +P + C A G+P P + W D P F+R H
Sbjct: 1986 LIVTVG--EPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIR--HP 2041
Query: 75 RVH-SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECL 130
V +AGVY C+ ++++ TA ++N + V + L S+ QG+ L C
Sbjct: 2042 NVGLGNAGVYTCKGSSAHATA-TKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICT 2100
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--------IA 182
S + W+K L D + + G L + + AG Y+C IA
Sbjct: 2101 ATGSSLVDRLEWEKVDDQLPTDVEEHN---EPGLLHFPSFKNSYAGEYRCNGYRNNEIIA 2157
Query: 183 RNAAGTRESAIAT--LKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239
A SA A K+ I+P P V G ++ +C V G + W
Sbjct: 2158 SAAVHVHSSANADDEPKVEIEP-----PRVRVVSQGDNIVLKCSVQGAENGEHFKWALLR 2212
Query: 240 GGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
GG + LG L+ N D G Y C E++ G V S + V
Sbjct: 2213 GGSLVRQLGTEPTLEITKADPSN----DFGVYRCNVEDNNGLVIGSAFTAVSVGQQDKSH 2268
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V + + A FTC P + W+ E P + AV +G + I
Sbjct: 2269 AQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGD---LP--------SKAVPNG-NKIEI 2316
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAV 416
+ D + S T VC V++ G+ V G VT+ P II S+++ I A
Sbjct: 2317 KEFD-DASAGTYVCK-VSFDGN-VVEG--FVTAQMFVPDTIIQVLLEVSSESPQIGDRAW 2371
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
F C P +I+W EG + + + VT G L+ DL + ++G Y CVA ++ G
Sbjct: 2372 FDCKVTGDPSAVISWTKEGNDDLPPNAQ-VTG-GRLLFTDLKEDNAGVYRCVAKTKAG 2427
Score = 60.5 bits (140), Expect = 7e-09
Identities = 103/435 (23%), Positives = 168/435 (38%), Gaps = 48/435 (11%)
Query: 79 DAGVYWCEATN--SYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+AG Y C AT Y T + + ++ + ++P +G+ C P G
Sbjct: 1194 NAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP-GI 1252
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
P+ + W + G + GN L I ++ AGRY C A N GT +S A
Sbjct: 1253 PDCQITWHREQ----LGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 195 TLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
L++ KP +I D + QT F+C V G+ + W R GG +P G +
Sbjct: 1309 VLEVK-KP-VIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRP-GGAPLPSGVQE- 1364
Query: 252 LDDGSLRLDNVILADEGEYSCEA---ENSVGAVSASGYLTVYDPP------SINLSPNSV 302
G L + + G+Y C A ++ S L + DP + + P +
Sbjct: 1365 -QQGILHIPRASDQEVGQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQ 1423
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V + A+F C G+P + WS + R + + RD + L I+ +
Sbjct: 1424 TVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPNGILERDGF-----------LRIDKSQ 1472
Query: 363 KNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
+D+ C++ GS+ + +L V P + P QT+ + C
Sbjct: 1473 LHDA-GEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQV---DPPVQTVNEGEPSRIRCW 1528
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS-RHGKYVWS 479
P + + G + H R + G L + KSD Y C+A+ + V S
Sbjct: 1529 VPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRTLKSDEDEYICIATDPTTNRPVES 1586
Query: 480 --GALLVDSPINPNI 492
++V SPI P I
Sbjct: 1587 NPARVIVKSPIRPII 1601
Score = 60.1 bits (139), Expect = 9e-09
Identities = 47/175 (26%), Positives = 70/175 (40%), Gaps = 12/175 (6%)
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGS 217
DG ++VI +A + G Y C A N GT + L++ P + P + G
Sbjct: 1842 DGDDIVISEAGDRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGE 1901
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAEN 276
F+C G P P + W G PL V L+ L N G+Y+C A N
Sbjct: 1902 RHQFRCITTGSPTPKITW---TGPNGSPLPHDVTPLEPNILDFSNGRSELNGDYTCTASN 1958
Query: 277 SVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTCT---ATGRPEPTMFW 326
+G S G + + ++ +P + V G + C A G PEP + W
Sbjct: 1959 PIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 2013
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 12/135 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLV 453
P ++ +N +P + C A+ PEP I W + + R T++ GTL
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGTLT 330
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ D D G YTC A + G+ + + +V +P P PPT P
Sbjct: 331 IHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPR---------PQPPQPPTAPPQR 381
Query: 514 NVTDTSVTLSWSQNN 528
DT ++ NN
Sbjct: 382 ASCDTRGAVTPYPNN 396
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 267 EGEYSC-EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+G C + + VG V TV DPP NL V G TC A PEP +
Sbjct: 254 DGTNDCHDGSDEVGCVQP----TVVDPPQTNLQ-----VPRGTTFSLTCKAVAVPEPYIN 304
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W + P + T+ G LTI+D D + C A+N G
Sbjct: 305 WRLNWG-----PVCEPPRCLQTSE-GGYGTLTIHDAQPVD-QGAYTCEAINVKGRVLATP 357
Query: 386 KLTV-TSDDDRPPP 398
V DD RP P
Sbjct: 358 DCIVRVVDDPRPQP 371
Score = 36.7 bits (81), Expect = 0.10
Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 8/142 (5%)
Query: 152 DGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
+GD V GN + I++ AG Y C + G T ++ + +I +
Sbjct: 2300 NGDLPSKAVPNGNKIEIKEFDDASAGTYVCKV-SFDGNVVEGFVTAQMFVPDTIIQVLLE 2358
Query: 211 VVA---QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
V + Q G F C+V GDP + W + GN L + G L ++ +
Sbjct: 2359 VSSESPQIGDRAWFDCKVTGDPSAVISWTKE---GNDDLPPNAQVTGGRLLFTDLKEDNA 2415
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A+ G + L V
Sbjct: 2416 GVYRCVAKTKAGPLQTRTVLNV 2437
Score = 35.5 bits (78), Expect = 0.23
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 208 PEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P + + G V+F+CR P V W R G PL G L ++ V L
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGG----PLPSSAHDSGGRLTINPVQL 106
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV--YDPPSIN 296
+D G Y C ++ + V A L+V Y P ++
Sbjct: 107 SDAGTYICVSDYNGNTVEARATLSVVSYGPQEVS 140
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 200 IKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
++P ++ P+ ++ G++ + C+ P P + WR + G P ++ + G +
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT 328
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSAS 284
L + + D+G Y+CEA N G V A+
Sbjct: 329 LTIHDAQPVDQGAYTCEAINVKGRVLAT 356
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 12 PYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P +++ P ++ V R +L C+A P P I W + V + R + + G +
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINW-RLNWGPVCEPPRCLQTSEGGYGTL 329
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
H D G Y CEA N G
Sbjct: 330 TIHDAQPVDQGAYTCEAINVKG 351
Score = 33.1 bits (72), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 114 PESKQSAQGDTVVLECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
P K+ G V EC S P V W + G L S H GG L I +
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL----PSSAH-DSGGRLTINPVQ 105
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI 198
+DAG Y C++ T E A ATL +
Sbjct: 106 LSDAGTYICVSDYNGNTVE-ARATLSV 131
Score = 32.3 bits (70), Expect = 2.2
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDA 175
Q +G T L C PEP + W+ N + + + +GG L I DA+ D
Sbjct: 282 QVPRGTTFSLTCKAV-AVPEPYINWRLNWGPVC-EPPRCLQTSEGGYGTLTIHDAQPVDQ 339
Query: 176 GRYQCIARNAAG 187
G Y C A N G
Sbjct: 340 GAYTCEAINVKG 351
>Z93375-9|CAH04704.1| 2389|Caenorhabditis elegans Hypothetical protein
ZC101.2f protein.
Length = 2389
Score = 91.1 bits (216), Expect = 4e-18
Identities = 128/489 (26%), Positives = 195/489 (39%), Gaps = 56/489 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G AP I P + TV + PA C G P ++W + + + IL G F
Sbjct: 1320 GAAPQI--DPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN---GILERDG--F 1372
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE-EFRLEPESKQSAQGDTVV 126
LR ++H DAG Y C +T G+ + S A L+V + + +++P + +G+
Sbjct: 1373 LRIDKSQLH-DAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQTVNEGEPSR 1431
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+ C P G P + + K G+ L +R GNL I ++D Y CIA +
Sbjct: 1432 IRCWVP-GHPNIQLQFVKRGRRPL-PAHARF---SQGNLEIPRTLKSDEDEYICIATDPT 1486
Query: 187 GTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
R ++ +K + I P + GS +C V G P + +RR +G N
Sbjct: 1487 TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVPGHPSVQLTFRRVSGQLNE 1546
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTVY-----DPPSIN-- 296
++G L + L DEG+Y C A + GA S TV+ PP +
Sbjct: 1547 DADE----NNGLLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEAR 1602
Query: 297 ------LSPNSVNVESGNVARFTCTATGRPEPTMFWSVE--GNRTIIFPGMSRDKYHATA 348
++P + + G+ AR CT G P S E + + F G S D+
Sbjct: 1603 PPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFERVDGKGLPF-GSSDDR----- 1656
Query: 349 VFDGVTVLTINDTDKNDSRNTI-VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
VLTI T D+ + + S N L VT + P P+ T P
Sbjct: 1657 -----GVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTPPRPVAT--PPLL 1709
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTY 465
++ S A F C A I W F E + H V DG +V+ + + G Y
Sbjct: 1710 SVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEH---VNQDGDDIVISEAGDRNVGEY 1766
Query: 466 TCVASSRHG 474
C A++ G
Sbjct: 1767 VCSATNDFG 1775
Score = 85.0 bits (201), Expect = 3e-16
Identities = 129/526 (24%), Positives = 193/526 (36%), Gaps = 56/526 (10%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAGG 65
G P + P + V +PA C G P I W++ GG L + G
Sbjct: 1130 GRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLP-----HGVYQTGN 1184
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
L+ ++H AG Y C A N YGT +S A L V +++P + +
Sbjct: 1185 A--LKIPQSQLHH-AGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQPA 1241
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
+C P G+ + W + G L G G L I A + G+Y C A +
Sbjct: 1242 RFKCWVP-GNSNVQLRWSRPGGAPLPSGVQEQQ----GILHIPRASDQEVGQYVCTATDP 1296
Query: 186 AGTRESAIATLKIHIK----PYLITGPE-DVVAQT---GSSVTFQCRVGGDPLPDVLWRR 237
+ ++++I+ P P+ D QT F+C V G P + W R
Sbjct: 1297 SDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWSR 1356
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--VSASGYLTVYDPPSI 295
G PL + DG LR+D L D GEY C + G+ +S L V P +I
Sbjct: 1357 KDG---RPLPNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQAI 1413
Query: 296 --NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGV 353
+ P V G +R C G P + + G R + P +R
Sbjct: 1414 QPQVDPPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPL--PAHARFSQGN------- 1464
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
L I T K+D + +C A + + V PII P+ QT+P S
Sbjct: 1465 --LEIPRTLKSD-EDEYICIATDPTTNRPVESNPARVIVKSPIRPII--DPAEQTVPEGS 1519
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRH 473
F P + F + N + N+G L ++ + +D G Y C A
Sbjct: 1520 --PFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-ENNGLLAVQRAELTDEGDYICTARDPD 1576
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPG-PPTKPITHNVTDT 518
+GA + +P +H AA + PP P+ T T
Sbjct: 1577 -----TGAPIDSTP--ATVHVTNAAAPPQVEARPPQHPVITPQTQT 1615
Score = 71.7 bits (168), Expect = 3e-12
Identities = 112/483 (23%), Positives = 181/483 (37%), Gaps = 52/483 (10%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
++ P+ TV +P+ + C G P+ +++ K G + R G L R
Sbjct: 1417 VDPPVQ-TVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRT--- 1470
Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVVLECLPP 132
+ SD Y C AT+ T R + +++ R ++P + +G + C P
Sbjct: 1471 -LKSDEDEYICIATDPT-TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVP 1528
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN--AAGTRE 190
G P + +++ L D D + G L +Q A TD G Y C AR+ +
Sbjct: 1529 -GHPSVQLTFRRVSGQLNEDADE-----NNGLLAVQRAELTDEGDYICTARDPDTGAPID 1582
Query: 191 SAIATL---------KIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRR 237
S AT+ ++ +P + + P+ G QC V G+P + + R
Sbjct: 1583 STPATVHVTNAAAPPQVEARPPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFER 1642
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC--EAENSVGAVSASGYLTVYD---P 292
G G +P G D G L + + L D GEY C ENS + L V P
Sbjct: 1643 VDGKG-LPFGSSD--DRGVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTP 1699
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P +P ++V G+ ARF C A + W + +++D D
Sbjct: 1700 PRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVNQDG-------DD 1752
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
+ + D + + VCSA N G+ V + + +D+ PP P
Sbjct: 1753 IVISEAGDRNVGE----YVCSATNDFGTG-VADPVRLEVTEDQEPPTAVVEPRTWNGKPG 1807
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
F C +P P I W + + H L + +G YTC AS+
Sbjct: 1808 ERHQFRCITTGSPTPKITWTGPNGSPLP-HDVTPLEPNILDFSNGRSELNGDYTCTASNP 1866
Query: 473 HGK 475
G+
Sbjct: 1867 IGE 1869
Score = 70.1 bits (164), Expect = 9e-12
Identities = 86/328 (26%), Positives = 129/328 (39%), Gaps = 32/328 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + P ++VA PA NC A IRW G + + G
Sbjct: 1697 GTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRW---GFREENGPLPEHVNQDGDDI 1753
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVV 126
+ + G + G Y C ATN +GT + L V +E +EP + G+
Sbjct: 1754 VISEAG--DRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQ 1811
Query: 127 LECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
C+ GSP P + W NG L D + ++ L + R G Y C A N
Sbjct: 1812 FRCITT-GSPTPKITWTGPNGSPLPHD----VTPLEPNILDFSNGRSELNGDYTCTASNP 1866
Query: 186 AGTRESAIATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRR 237
G A ++I P L GP+ +V G + +C GDP P+V W
Sbjct: 1867 IG---EASDHGNVNIGPSLTVKTNPPGPKLIVT-VGEPLQVKCEAFGAPGDPEPEVEWLH 1922
Query: 238 SAGG--GNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
G G++P V + + +R NV L + G Y+C+ ++ + + Y+ V +P
Sbjct: 1923 DPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHATATKNIYIEVVEPSR 1982
Query: 295 IN----LSPNSVNVESGNVARFTCTATG 318
I L +S + G CTATG
Sbjct: 1983 IATVSILGGSSQWFDQGEKGELICTATG 2010
Score = 62.9 bits (146), Expect = 1e-09
Identities = 123/478 (25%), Positives = 185/478 (38%), Gaps = 58/478 (12%)
Query: 19 LDVTVARHQPATLNCRAGGSPS---PAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHG 74
L VTV +P + C A G+P P + W D P F+R H
Sbjct: 1893 LIVTVG--EPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIR--HP 1948
Query: 75 RVH-SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECL 130
V +AGVY C+ ++++ TA ++N + V + L S+ QG+ L C
Sbjct: 1949 NVGLGNAGVYTCKGSSAHATA-TKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICT 2007
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--------IA 182
S + W+K L D + + G L + + AG Y+C IA
Sbjct: 2008 ATGSSLVDRLEWEKVDDQLPTDVEEHN---EPGLLHFPSFKNSYAGEYRCNGYRNNEIIA 2064
Query: 183 RNAAGTRESAIAT--LKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239
A SA A K+ I+P P V G ++ +C V G + W
Sbjct: 2065 SAAVHVHSSANADDEPKVEIEP-----PRVRVVSQGDNIVLKCSVQGAENGEHFKWALLR 2119
Query: 240 GGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
GG + LG L+ N D G Y C E++ G V S + V
Sbjct: 2120 GGSLVRQLGTEPTLEITKADPSN----DFGVYRCNVEDNNGLVIGSAFTAVSVGQQDKSH 2175
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V + + A FTC P + W+ E P + AV +G + I
Sbjct: 2176 AQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGD---LP--------SKAVPNG-NKIEI 2223
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAV 416
+ D + S T VC V++ G+ V G VT+ P II S+++ I A
Sbjct: 2224 KEFD-DASAGTYVCK-VSFDGN-VVEG--FVTAQMFVPDTIIQVLLEVSSESPQIGDRAW 2278
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
F C P +I+W EG + + + VT G L+ DL + ++G Y CVA ++ G
Sbjct: 2279 FDCKVTGDPSAVISWTKEGNDDLPPNAQ-VTG-GRLLFTDLKEDNAGVYRCVAKTKAG 2334
Score = 60.1 bits (139), Expect = 9e-09
Identities = 47/175 (26%), Positives = 70/175 (40%), Gaps = 12/175 (6%)
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGS 217
DG ++VI +A + G Y C A N GT + L++ P + P + G
Sbjct: 1749 DGDDIVISEAGDRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGE 1808
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAEN 276
F+C G P P + W G PL V L+ L N G+Y+C A N
Sbjct: 1809 RHQFRCITTGSPTPKITW---TGPNGSPLPHDVTPLEPNILDFSNGRSELNGDYTCTASN 1865
Query: 277 SVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTCT---ATGRPEPTMFW 326
+G S G + + ++ +P + V G + C A G PEP + W
Sbjct: 1866 PIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 1920
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 12/135 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLV 453
P ++ +N +P + C A+ PEP I W + + R T++ GTL
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGTLT 330
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ D D G YTC A + G+ + + +V +P P PPT P
Sbjct: 331 IHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPR---------PQPPQPPTAPPQR 381
Query: 514 NVTDTSVTLSWSQNN 528
DT ++ NN
Sbjct: 382 ASCDTRGAVTPYPNN 396
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 267 EGEYSC-EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+G C + + VG V TV DPP NL V G TC A PEP +
Sbjct: 254 DGTNDCHDGSDEVGCVQP----TVVDPPQTNLQ-----VPRGTTFSLTCKAVAVPEPYIN 304
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W + P + T+ G LTI+D D + C A+N G
Sbjct: 305 WRLNWG-----PVCEPPRCLQTSE-GGYGTLTIHDAQPVD-QGAYTCEAINVKGRVLATP 357
Query: 386 KLTV-TSDDDRPPP 398
V DD RP P
Sbjct: 358 DCIVRVVDDPRPQP 371
Score = 36.7 bits (81), Expect = 0.10
Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 8/142 (5%)
Query: 152 DGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
+GD V GN + I++ AG Y C + G T ++ + +I +
Sbjct: 2207 NGDLPSKAVPNGNKIEIKEFDDASAGTYVCKV-SFDGNVVEGFVTAQMFVPDTIIQVLLE 2265
Query: 211 VVA---QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
V + Q G F C+V GDP + W + GN L + G L ++ +
Sbjct: 2266 VSSESPQIGDRAWFDCKVTGDPSAVISWTKE---GNDDLPPNAQVTGGRLLFTDLKEDNA 2322
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A+ G + L V
Sbjct: 2323 GVYRCVAKTKAGPLQTRTVLNV 2344
Score = 35.5 bits (78), Expect = 0.23
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 208 PEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P + + G V+F+CR P V W R G PL G L ++ V L
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGG----PLPSSAHDSGGRLTINPVQL 106
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV--YDPPSIN 296
+D G Y C ++ + V A L+V Y P ++
Sbjct: 107 SDAGTYICVSDYNGNTVEARATLSVVSYGPQEVS 140
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 200 IKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
++P ++ P+ ++ G++ + C+ P P + WR + G P ++ + G +
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT 328
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSAS 284
L + + D+G Y+CEA N G V A+
Sbjct: 329 LTIHDAQPVDQGAYTCEAINVKGRVLAT 356
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 12 PYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P +++ P ++ V R +L C+A P P I W + V + R + + G +
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINW-RLNWGPVCEPPRCLQTSEGGYGTL 329
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
H D G Y CEA N G
Sbjct: 330 TIHDAQPVDQGAYTCEAINVKG 351
Score = 33.1 bits (72), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 114 PESKQSAQGDTVVLECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
P K+ G V EC S P V W + G L S H GG L I +
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL----PSSAH-DSGGRLTINPVQ 105
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI 198
+DAG Y C++ T E A ATL +
Sbjct: 106 LSDAGTYICVSDYNGNTVE-ARATLSV 131
Score = 32.3 bits (70), Expect = 2.2
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDA 175
Q +G T L C PEP + W+ N + + + +GG L I DA+ D
Sbjct: 282 QVPRGTTFSLTCKAV-AVPEPYINWRLNWGPVC-EPPRCLQTSEGGYGTLTIHDAQPVDQ 339
Query: 176 GRYQCIARNAAG 187
G Y C A N G
Sbjct: 340 GAYTCEAINVKG 351
>Z93375-8|CAB07569.1| 3375|Caenorhabditis elegans Hypothetical protein
ZC101.2e protein.
Length = 3375
Score = 91.1 bits (216), Expect = 4e-18
Identities = 128/489 (26%), Positives = 195/489 (39%), Gaps = 56/489 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G AP I P + TV + PA C G P ++W + + + IL G F
Sbjct: 1413 GAAPQI--DPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN---GILERDG--F 1465
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE-EFRLEPESKQSAQGDTVV 126
LR ++H DAG Y C +T G+ + S A L+V + + +++P + +G+
Sbjct: 1466 LRIDKSQLH-DAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQTVNEGEPSR 1524
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+ C P G P + + K G+ L +R GNL I ++D Y CIA +
Sbjct: 1525 IRCWVP-GHPNIQLQFVKRGRRPL-PAHARF---SQGNLEIPRTLKSDEDEYICIATDPT 1579
Query: 187 GTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
R ++ +K + I P + GS +C V G P + +RR +G N
Sbjct: 1580 TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVPGHPSVQLTFRRVSGQLNE 1639
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTVY-----DPPSIN-- 296
++G L + L DEG+Y C A + GA S TV+ PP +
Sbjct: 1640 DADE----NNGLLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEAR 1695
Query: 297 ------LSPNSVNVESGNVARFTCTATGRPEPTMFWSVE--GNRTIIFPGMSRDKYHATA 348
++P + + G+ AR CT G P S E + + F G S D+
Sbjct: 1696 PPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFERVDGKGLPF-GSSDDR----- 1749
Query: 349 VFDGVTVLTINDTDKNDSRNTI-VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
VLTI T D+ + + S N L VT + P P+ T P
Sbjct: 1750 -----GVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTPPRPVAT--PPLL 1802
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTY 465
++ S A F C A I W F E + H V DG +V+ + + G Y
Sbjct: 1803 SVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEH---VNQDGDDIVISEAGDRNVGEY 1859
Query: 466 TCVASSRHG 474
C A++ G
Sbjct: 1860 VCSATNDFG 1868
Score = 86.6 bits (205), Expect = 9e-17
Identities = 130/527 (24%), Positives = 194/527 (36%), Gaps = 56/527 (10%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAG 64
SG P + P + V +PA C G P I W++ GG L + G
Sbjct: 1222 SGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLP-----HGVYQTG 1276
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L+ ++H AG Y C A N YGT +S A L V +++P + +
Sbjct: 1277 NA--LKIPQSQLHH-AGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQP 1333
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+C P G+ + W + G L G G L I A + G+Y C A +
Sbjct: 1334 ARFKCWVP-GNSNVQLRWSRPGGAPLPSGVQEQQ----GILHIPRASDQEVGQYVCTATD 1388
Query: 185 AAGTRESAIATLKIHIK----PYLITGPE-DVVAQT---GSSVTFQCRVGGDPLPDVLWR 236
+ ++++I+ P P+ D QT F+C V G P + W
Sbjct: 1389 PSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWS 1448
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--VSASGYLTVYDPPS 294
R G PL + DG LR+D L D GEY C + G+ +S L V P +
Sbjct: 1449 RKDG---RPLPNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQA 1505
Query: 295 I--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I + P V G +R C G P + + G R + P +R
Sbjct: 1506 IQPQVDPPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPL--PAHARFSQGN------ 1557
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I T K+D + +C A + + V PII P+ QT+P
Sbjct: 1558 ---LEIPRTLKSD-EDEYICIATDPTTNRPVESNPARVIVKSPIRPII--DPAEQTVPEG 1611
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
S F P + F + N + N+G L ++ + +D G Y C A
Sbjct: 1612 S--PFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-ENNGLLAVQRAELTDEGDYICTARDP 1668
Query: 473 HGKYVWSGALLVDSPINPNIHFFRAADVSSLPG-PPTKPITHNVTDT 518
+GA + +P +H AA + PP P+ T T
Sbjct: 1669 D-----TGAPIDSTP--ATVHVTNAAAPPQVEARPPQHPVITPQTQT 1708
Score = 71.7 bits (168), Expect = 3e-12
Identities = 85/374 (22%), Positives = 142/374 (37%), Gaps = 31/374 (8%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170
+EP+ + + GD V C + E +V W K G+ L +++ + G LV++
Sbjct: 1135 MEPKRQIALPGDRVHWICQVTGYTTEKIHVEWTKVGEMSL-PPNAKAY---DGYLVLKGV 1190
Query: 171 RQTDAGRYQCIARNAAG-TRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVG 226
+AG+Y+C A + A+ T+ I P + P +V G F+C V
Sbjct: 1191 EAENAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP 1250
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
G P + W R GG +P G + +L++ L G Y C A N G +
Sbjct: 1251 GIPDCQITWHREQLGGPLPHGVYQT--GNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 287 LTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
+ P I + P V+ ARF C G + WS G +
Sbjct: 1309 VLEVKKPVIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRPGGAPL---------- 1358
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----II 400
+ V + +L I + VC+A + + ++ ++ + + D PP
Sbjct: 1359 -PSGVQEQQGILHIPRASDQEV-GQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAP 1416
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
P NQT+ + A F C P + W + + N + DG L +
Sbjct: 1417 QIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN--GILERDGFLRIDKSQLH 1474
Query: 461 DSGTYTCVASSRHG 474
D+G Y C ++ G
Sbjct: 1475 DAGEYECTSTEPDG 1488
Score = 71.7 bits (168), Expect = 3e-12
Identities = 112/483 (23%), Positives = 181/483 (37%), Gaps = 52/483 (10%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
++ P+ TV +P+ + C G P+ +++ K G + R G L R
Sbjct: 1510 VDPPVQ-TVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRT--- 1563
Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVVLECLPP 132
+ SD Y C AT+ T R + +++ R ++P + +G + C P
Sbjct: 1564 -LKSDEDEYICIATDPT-TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVP 1621
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN--AAGTRE 190
G P + +++ L D D + G L +Q A TD G Y C AR+ +
Sbjct: 1622 -GHPSVQLTFRRVSGQLNEDADE-----NNGLLAVQRAELTDEGDYICTARDPDTGAPID 1675
Query: 191 SAIATL---------KIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRR 237
S AT+ ++ +P + + P+ G QC V G+P + + R
Sbjct: 1676 STPATVHVTNAAAPPQVEARPPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFER 1735
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC--EAENSVGAVSASGYLTVYD---P 292
G G +P G D G L + + L D GEY C ENS + L V P
Sbjct: 1736 VDGKG-LPFGSSD--DRGVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTP 1792
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P +P ++V G+ ARF C A + W + +++D D
Sbjct: 1793 PRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVNQDG-------DD 1845
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
+ + D + + VCSA N G+ V + + +D+ PP P
Sbjct: 1846 IVISEAGDRNVGE----YVCSATNDFGTG-VADPVRLEVTEDQEPPTAVVEPRTWNGKPG 1900
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
F C +P P I W + + H L + +G YTC AS+
Sbjct: 1901 ERHQFRCITTGSPTPKITWTGPNGSPLP-HDVTPLEPNILDFSNGRSELNGDYTCTASNP 1959
Query: 473 HGK 475
G+
Sbjct: 1960 IGE 1962
Score = 70.1 bits (164), Expect = 9e-12
Identities = 86/328 (26%), Positives = 129/328 (39%), Gaps = 32/328 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + P ++VA PA NC A IRW G + + G
Sbjct: 1790 GTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRW---GFREENGPLPEHVNQDGDDI 1846
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVV 126
+ + G + G Y C ATN +GT + L V +E +EP + G+
Sbjct: 1847 VISEAG--DRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQ 1904
Query: 127 LECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
C+ GSP P + W NG L D + ++ L + R G Y C A N
Sbjct: 1905 FRCITT-GSPTPKITWTGPNGSPLPHD----VTPLEPNILDFSNGRSELNGDYTCTASNP 1959
Query: 186 AGTRESAIATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRR 237
G A ++I P L GP+ +V G + +C GDP P+V W
Sbjct: 1960 IG---EASDHGNVNIGPSLTVKTNPPGPKLIVT-VGEPLQVKCEAFGAPGDPEPEVEWLH 2015
Query: 238 SAGG--GNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
G G++P V + + +R NV L + G Y+C+ ++ + + Y+ V +P
Sbjct: 2016 DPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHATATKNIYIEVVEPSR 2075
Query: 295 IN----LSPNSVNVESGNVARFTCTATG 318
I L +S + G CTATG
Sbjct: 2076 IATVSILGGSSQWFDQGEKGELICTATG 2103
Score = 62.9 bits (146), Expect = 1e-09
Identities = 123/478 (25%), Positives = 185/478 (38%), Gaps = 58/478 (12%)
Query: 19 LDVTVARHQPATLNCRAGGSPS---PAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHG 74
L VTV +P + C A G+P P + W D P F+R H
Sbjct: 1986 LIVTVG--EPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIR--HP 2041
Query: 75 RVH-SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECL 130
V +AGVY C+ ++++ TA ++N + V + L S+ QG+ L C
Sbjct: 2042 NVGLGNAGVYTCKGSSAHATA-TKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICT 2100
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--------IA 182
S + W+K L D + + G L + + AG Y+C IA
Sbjct: 2101 ATGSSLVDRLEWEKVDDQLPTDVEEHN---EPGLLHFPSFKNSYAGEYRCNGYRNNEIIA 2157
Query: 183 RNAAGTRESAIAT--LKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239
A SA A K+ I+P P V G ++ +C V G + W
Sbjct: 2158 SAAVHVHSSANADDEPKVEIEP-----PRVRVVSQGDNIVLKCSVQGAENGEHFKWALLR 2212
Query: 240 GGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
GG + LG L+ N D G Y C E++ G V S + V
Sbjct: 2213 GGSLVRQLGTEPTLEITKADPSN----DFGVYRCNVEDNNGLVIGSAFTAVSVGQQDKSH 2268
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V + + A FTC P + W+ E P + AV +G + I
Sbjct: 2269 AQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGD---LP--------SKAVPNG-NKIEI 2316
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAV 416
+ D + S T VC V++ G+ V G VT+ P II S+++ I A
Sbjct: 2317 KEFD-DASAGTYVCK-VSFDGN-VVEG--FVTAQMFVPDTIIQVLLEVSSESPQIGDRAW 2371
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
F C P +I+W EG + + + VT G L+ DL + ++G Y CVA ++ G
Sbjct: 2372 FDCKVTGDPSAVISWTKEGNDDLPPNAQ-VTG-GRLLFTDLKEDNAGVYRCVAKTKAG 2427
Score = 60.5 bits (140), Expect = 7e-09
Identities = 103/435 (23%), Positives = 168/435 (38%), Gaps = 48/435 (11%)
Query: 79 DAGVYWCEATN--SYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+AG Y C AT Y T + + ++ + ++P +G+ C P G
Sbjct: 1194 NAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP-GI 1252
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
P+ + W + G + GN L I ++ AGRY C A N GT +S A
Sbjct: 1253 PDCQITWHREQ----LGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 195 TLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
L++ KP +I D + QT F+C V G+ + W R GG +P G +
Sbjct: 1309 VLEVK-KP-VIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRP-GGAPLPSGVQE- 1364
Query: 252 LDDGSLRLDNVILADEGEYSCEA---ENSVGAVSASGYLTVYDPP------SINLSPNSV 302
G L + + G+Y C A ++ S L + DP + + P +
Sbjct: 1365 -QQGILHIPRASDQEVGQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQ 1423
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V + A+F C G+P + WS + R + + RD + L I+ +
Sbjct: 1424 TVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPNGILERDGF-----------LRIDKSQ 1472
Query: 363 KNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
+D+ C++ GS+ + +L V P + P QT+ + C
Sbjct: 1473 LHDA-GEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQV---DPPVQTVNEGEPSRIRCW 1528
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS-RHGKYVWS 479
P + + G + H R + G L + KSD Y C+A+ + V S
Sbjct: 1529 VPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRTLKSDEDEYICIATDPTTNRPVES 1586
Query: 480 --GALLVDSPINPNI 492
++V SPI P I
Sbjct: 1587 NPARVIVKSPIRPII 1601
Score = 60.1 bits (139), Expect = 9e-09
Identities = 47/175 (26%), Positives = 70/175 (40%), Gaps = 12/175 (6%)
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGS 217
DG ++VI +A + G Y C A N GT + L++ P + P + G
Sbjct: 1842 DGDDIVISEAGDRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGE 1901
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAEN 276
F+C G P P + W G PL V L+ L N G+Y+C A N
Sbjct: 1902 RHQFRCITTGSPTPKITW---TGPNGSPLPHDVTPLEPNILDFSNGRSELNGDYTCTASN 1958
Query: 277 SVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTCT---ATGRPEPTMFW 326
+G S G + + ++ +P + V G + C A G PEP + W
Sbjct: 1959 PIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 2013
Score = 57.2 bits (132), Expect = 7e-08
Identities = 71/292 (24%), Positives = 113/292 (38%), Gaps = 23/292 (7%)
Query: 78 SDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
+ AG Y C+ + A + V + LE S+ GD +C G P
Sbjct: 2322 ASAGTYVCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGDRAWFDC-KVTGDP 2380
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESA---- 192
+ W K G L V GG L+ D ++ +AG Y+C+A+ AG ++
Sbjct: 2381 SAVISWTKEGNDDLPPNAQ----VTGGRLLFTDLKEDNAGVYRCVAKTKAGPLQTRTVLN 2436
Query: 193 IATLKIHIKPYLITGPEDVVAQTGSSVTFQC--RVGGDPLPDVLWRRSAGGGNMPLGRVK 250
+ + K + + VV G C + P V+W + G++P G
Sbjct: 2437 VGSGKQDQVTFTVADSLPVVYTVGQPAYLSCIGKTETKPNQSVVWTKEE--GDLPSG--S 2492
Query: 251 VLDDGSLRLDNVILADEGEYSCE---AENSVGA---VSASGYLTVYDPPSINLSPNSVNV 304
++ G L L +V DEG Y+CE EN V + + ++ V D I L P S +
Sbjct: 2493 RVEQGVLMLPSVHRDDEGSYTCEIVKEENPVFSTVDLQIDDFIPVIDGEPIELPPLS-DE 2551
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
E N+ T P+ +F + N + +H + D TVL
Sbjct: 2552 EIVNLDIEITLNTANPKGIIFETKRINSGDLLATPYDTIHHEAKITDYGTVL 2603
Score = 46.0 bits (104), Expect = 2e-04
Identities = 90/401 (22%), Positives = 136/401 (33%), Gaps = 35/401 (8%)
Query: 77 HSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRLE---PESKQSAQGDTVVLECLPP 132
+S AG Y C + S +H + +E ++E P + +QGD +VL+C
Sbjct: 2139 NSYAGEYRCNGYRNNEIIASAAVHVHSSANADDEPKVEIEPPRVRVVSQGDNIVLKCSVQ 2198
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA-RQTDAGRYQCIARNAAGTRES 191
+ W LL G L L I A D G Y+C + G
Sbjct: 2199 GAENGEHFKW-----ALLRGGSLVRQLGTEPTLEITKADPSNDFGVYRCNVEDNNGLVIG 2253
Query: 192 AIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
+ T + + + + V S +F C + P V W + G++P V
Sbjct: 2254 SAFT-AVSVGQQDKSHAQIVKFDDKSDASFTCPIYSVPGSKVDW--TYENGDLPSKAVP- 2309
Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI---NLSPNSVNVESGN 308
+ + + A G Y C+ V ++ P +I L +S + + G+
Sbjct: 2310 -NGNKIEIKEFDDASAGTYVCKVSFDGNVVEGFVTAQMFVPDTIIQVLLEVSSESPQIGD 2368
Query: 309 VARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRN 368
A F C TG P + W+ EGN D A G +L D K D+
Sbjct: 2369 RAWFDCKVTGDPSAVISWTKEGN----------DDLPPNAQVTGGRLL-FTDL-KEDNAG 2416
Query: 369 TIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP- 427
C A AG R L V S + A C +P
Sbjct: 2417 VYRCVAKTKAGPLQTRTVLNVGSGKQDQVTFTVADSLPVVYTVGQPAYLSCIGKTETKPN 2476
Query: 428 -IIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
+ W E L R G L+L + + D G+YTC
Sbjct: 2477 QSVVWTKEEGDLPSGSR---VEQGVLMLPSVHRDDEGSYTC 2514
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 12/135 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLV 453
P ++ +N +P + C A+ PEP I W + + R T++ GTL
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGTLT 330
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ D D G YTC A + G+ + + +V +P P PPT P
Sbjct: 331 IHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPR---------PQPPQPPTAPPQR 381
Query: 514 NVTDTSVTLSWSQNN 528
DT ++ NN
Sbjct: 382 ASCDTRGAVTPYPNN 396
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 267 EGEYSC-EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+G C + + VG V TV DPP NL V G TC A PEP +
Sbjct: 254 DGTNDCHDGSDEVGCVQP----TVVDPPQTNLQ-----VPRGTTFSLTCKAVAVPEPYIN 304
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W + P + T+ G LTI+D D + C A+N G
Sbjct: 305 WRLNWG-----PVCEPPRCLQTSE-GGYGTLTIHDAQPVD-QGAYTCEAINVKGRVLATP 357
Query: 386 KLTV-TSDDDRPPP 398
V DD RP P
Sbjct: 358 DCIVRVVDDPRPQP 371
Score = 35.5 bits (78), Expect = 0.23
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 208 PEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P + + G V+F+CR P V W R G PL G L ++ V L
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGG----PLPSSAHDSGGRLTINPVQL 106
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV--YDPPSIN 296
+D G Y C ++ + V A L+V Y P ++
Sbjct: 107 SDAGTYICVSDYNGNTVEARATLSVVSYGPQEVS 140
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 200 IKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
++P ++ P+ ++ G++ + C+ P P + WR + G P ++ + G +
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT 328
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSAS 284
L + + D+G Y+CEA N G V A+
Sbjct: 329 LTIHDAQPVDQGAYTCEAINVKGRVLAT 356
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 12 PYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P +++ P ++ V R +L C+A P P I W + V + R + + G +
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINW-RLNWGPVCEPPRCLQTSEGGYGTL 329
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
H D G Y CEA N G
Sbjct: 330 TIHDAQPVDQGAYTCEAINVKG 351
Score = 33.1 bits (72), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 114 PESKQSAQGDTVVLECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
P K+ G V EC S P V W + G L S H GG L I +
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL----PSSAH-DSGGRLTINPVQ 105
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI 198
+DAG Y C++ T E A ATL +
Sbjct: 106 LSDAGTYICVSDYNGNTVE-ARATLSV 131
Score = 32.3 bits (70), Expect = 2.2
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDA 175
Q +G T L C PEP + W+ N + + + +GG L I DA+ D
Sbjct: 282 QVPRGTTFSLTCKAV-AVPEPYINWRLNWGPVC-EPPRCLQTSEGGYGTLTIHDAQPVDQ 339
Query: 176 GRYQCIARNAAG 187
G Y C A N G
Sbjct: 340 GAYTCEAINVKG 351
Score = 31.5 bits (68), Expect = 3.8
Identities = 40/157 (25%), Positives = 58/157 (36%), Gaps = 17/157 (10%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A +C+ G PS I W K G D + GG +AGVY C A
Sbjct: 2370 AWFDCKVTGDPSAVISWTKEG---NDDLPPNAQVTGGRLLFTDLK---EDNAGVYRCVAK 2423
Query: 89 NSYGTARSRNATLHVAVLREE---FRL-EPESKQSAQGDTVVLECL-PPRGSPEPNVYWK 143
G ++R L+V +++ F + + G L C+ P +V W
Sbjct: 2424 TKAGPLQTR-TVLNVGSGKQDQVTFTVADSLPVVYTVGQPAYLSCIGKTETKPNQSVVWT 2482
Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
K L SR V+ G L++ + D G Y C
Sbjct: 2483 KEEGDL--PSGSR---VEQGVLMLPSVHRDDEGSYTC 2514
>Z93375-6|CAB07567.1| 2482|Caenorhabditis elegans Hypothetical protein
ZC101.2a protein.
Length = 2482
Score = 91.1 bits (216), Expect = 4e-18
Identities = 128/489 (26%), Positives = 195/489 (39%), Gaps = 56/489 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G AP I P + TV + PA C G P ++W + + + IL G F
Sbjct: 1413 GAAPQI--DPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN---GILERDG--F 1465
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE-EFRLEPESKQSAQGDTVV 126
LR ++H DAG Y C +T G+ + S A L+V + + +++P + +G+
Sbjct: 1466 LRIDKSQLH-DAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQTVNEGEPSR 1524
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+ C P G P + + K G+ L +R GNL I ++D Y CIA +
Sbjct: 1525 IRCWVP-GHPNIQLQFVKRGRRPL-PAHARF---SQGNLEIPRTLKSDEDEYICIATDPT 1579
Query: 187 GTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
R ++ +K + I P + GS +C V G P + +RR +G N
Sbjct: 1580 TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVPGHPSVQLTFRRVSGQLNE 1639
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTVY-----DPPSIN-- 296
++G L + L DEG+Y C A + GA S TV+ PP +
Sbjct: 1640 DADE----NNGLLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEAR 1695
Query: 297 ------LSPNSVNVESGNVARFTCTATGRPEPTMFWSVE--GNRTIIFPGMSRDKYHATA 348
++P + + G+ AR CT G P S E + + F G S D+
Sbjct: 1696 PPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFERVDGKGLPF-GSSDDR----- 1749
Query: 349 VFDGVTVLTINDTDKNDSRNTI-VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
VLTI T D+ + + S N L VT + P P+ T P
Sbjct: 1750 -----GVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTPPRPVAT--PPLL 1802
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTY 465
++ S A F C A I W F E + H V DG +V+ + + G Y
Sbjct: 1803 SVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEH---VNQDGDDIVISEAGDRNVGEY 1859
Query: 466 TCVASSRHG 474
C A++ G
Sbjct: 1860 VCSATNDFG 1868
Score = 86.6 bits (205), Expect = 9e-17
Identities = 130/527 (24%), Positives = 194/527 (36%), Gaps = 56/527 (10%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAG 64
SG P + P + V +PA C G P I W++ GG L + G
Sbjct: 1222 SGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLP-----HGVYQTG 1276
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L+ ++H AG Y C A N YGT +S A L V +++P + +
Sbjct: 1277 NA--LKIPQSQLHH-AGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQP 1333
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+C P G+ + W + G L G G L I A + G+Y C A +
Sbjct: 1334 ARFKCWVP-GNSNVQLRWSRPGGAPLPSGVQEQQ----GILHIPRASDQEVGQYVCTATD 1388
Query: 185 AAGTRESAIATLKIHIK----PYLITGPE-DVVAQT---GSSVTFQCRVGGDPLPDVLWR 236
+ ++++I+ P P+ D QT F+C V G P + W
Sbjct: 1389 PSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWS 1448
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--VSASGYLTVYDPPS 294
R G PL + DG LR+D L D GEY C + G+ +S L V P +
Sbjct: 1449 RKDG---RPLPNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQA 1505
Query: 295 I--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I + P V G +R C G P + + G R + P +R
Sbjct: 1506 IQPQVDPPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPL--PAHARFSQGN------ 1557
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I T K+D + +C A + + V PII P+ QT+P
Sbjct: 1558 ---LEIPRTLKSD-EDEYICIATDPTTNRPVESNPARVIVKSPIRPII--DPAEQTVPEG 1611
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
S F P + F + N + N+G L ++ + +D G Y C A
Sbjct: 1612 S--PFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-ENNGLLAVQRAELTDEGDYICTARDP 1668
Query: 473 HGKYVWSGALLVDSPINPNIHFFRAADVSSLPG-PPTKPITHNVTDT 518
+GA + +P +H AA + PP P+ T T
Sbjct: 1669 D-----TGAPIDSTP--ATVHVTNAAAPPQVEARPPQHPVITPQTQT 1708
Score = 71.7 bits (168), Expect = 3e-12
Identities = 85/374 (22%), Positives = 142/374 (37%), Gaps = 31/374 (8%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170
+EP+ + + GD V C + E +V W K G+ L +++ + G LV++
Sbjct: 1135 MEPKRQIALPGDRVHWICQVTGYTTEKIHVEWTKVGEMSL-PPNAKAY---DGYLVLKGV 1190
Query: 171 RQTDAGRYQCIARNAAG-TRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVG 226
+AG+Y+C A + A+ T+ I P + P +V G F+C V
Sbjct: 1191 EAENAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP 1250
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
G P + W R GG +P G + +L++ L G Y C A N G +
Sbjct: 1251 GIPDCQITWHREQLGGPLPHGVYQT--GNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 287 LTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
+ P I + P V+ ARF C G + WS G +
Sbjct: 1309 VLEVKKPVIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRPGGAPL---------- 1358
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----II 400
+ V + +L I + VC+A + + ++ ++ + + D PP
Sbjct: 1359 -PSGVQEQQGILHIPRASDQEV-GQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAP 1416
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
P NQT+ + A F C P + W + + N + DG L +
Sbjct: 1417 QIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN--GILERDGFLRIDKSQLH 1474
Query: 461 DSGTYTCVASSRHG 474
D+G Y C ++ G
Sbjct: 1475 DAGEYECTSTEPDG 1488
Score = 71.7 bits (168), Expect = 3e-12
Identities = 112/483 (23%), Positives = 181/483 (37%), Gaps = 52/483 (10%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
++ P+ TV +P+ + C G P+ +++ K G + R G L R
Sbjct: 1510 VDPPVQ-TVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRT--- 1563
Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVVLECLPP 132
+ SD Y C AT+ T R + +++ R ++P + +G + C P
Sbjct: 1564 -LKSDEDEYICIATDPT-TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVP 1621
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN--AAGTRE 190
G P + +++ L D D + G L +Q A TD G Y C AR+ +
Sbjct: 1622 -GHPSVQLTFRRVSGQLNEDADE-----NNGLLAVQRAELTDEGDYICTARDPDTGAPID 1675
Query: 191 SAIATL---------KIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRR 237
S AT+ ++ +P + + P+ G QC V G+P + + R
Sbjct: 1676 STPATVHVTNAAAPPQVEARPPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFER 1735
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC--EAENSVGAVSASGYLTVYD---P 292
G G +P G D G L + + L D GEY C ENS + L V P
Sbjct: 1736 VDGKG-LPFGSSD--DRGVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTP 1792
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P +P ++V G+ ARF C A + W + +++D D
Sbjct: 1793 PRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVNQDG-------DD 1845
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
+ + D + + VCSA N G+ V + + +D+ PP P
Sbjct: 1846 IVISEAGDRNVGE----YVCSATNDFGTG-VADPVRLEVTEDQEPPTAVVEPRTWNGKPG 1900
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
F C +P P I W + + H L + +G YTC AS+
Sbjct: 1901 ERHQFRCITTGSPTPKITWTGPNGSPLP-HDVTPLEPNILDFSNGRSELNGDYTCTASNP 1959
Query: 473 HGK 475
G+
Sbjct: 1960 IGE 1962
Score = 70.1 bits (164), Expect = 9e-12
Identities = 86/328 (26%), Positives = 129/328 (39%), Gaps = 32/328 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + P ++VA PA NC A IRW G + + G
Sbjct: 1790 GTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRW---GFREENGPLPEHVNQDGDDI 1846
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVV 126
+ + G + G Y C ATN +GT + L V +E +EP + G+
Sbjct: 1847 VISEAG--DRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQ 1904
Query: 127 LECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
C+ GSP P + W NG L D + ++ L + R G Y C A N
Sbjct: 1905 FRCITT-GSPTPKITWTGPNGSPLPHD----VTPLEPNILDFSNGRSELNGDYTCTASNP 1959
Query: 186 AGTRESAIATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRR 237
G A ++I P L GP+ +V G + +C GDP P+V W
Sbjct: 1960 IG---EASDHGNVNIGPSLTVKTNPPGPKLIVT-VGEPLQVKCEAFGAPGDPEPEVEWLH 2015
Query: 238 SAGG--GNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
G G++P V + + +R NV L + G Y+C+ ++ + + Y+ V +P
Sbjct: 2016 DPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHATATKNIYIEVVEPSR 2075
Query: 295 IN----LSPNSVNVESGNVARFTCTATG 318
I L +S + G CTATG
Sbjct: 2076 IATVSILGGSSQWFDQGEKGELICTATG 2103
Score = 62.9 bits (146), Expect = 1e-09
Identities = 123/478 (25%), Positives = 185/478 (38%), Gaps = 58/478 (12%)
Query: 19 LDVTVARHQPATLNCRAGGSPS---PAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHG 74
L VTV +P + C A G+P P + W D P F+R H
Sbjct: 1986 LIVTVG--EPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIR--HP 2041
Query: 75 RVH-SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECL 130
V +AGVY C+ ++++ TA ++N + V + L S+ QG+ L C
Sbjct: 2042 NVGLGNAGVYTCKGSSAHATA-TKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICT 2100
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--------IA 182
S + W+K L D + + G L + + AG Y+C IA
Sbjct: 2101 ATGSSLVDRLEWEKVDDQLPTDVEEHN---EPGLLHFPSFKNSYAGEYRCNGYRNNEIIA 2157
Query: 183 RNAAGTRESAIAT--LKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239
A SA A K+ I+P P V G ++ +C V G + W
Sbjct: 2158 SAAVHVHSSANADDEPKVEIEP-----PRVRVVSQGDNIVLKCSVQGAENGEHFKWALLR 2212
Query: 240 GGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
GG + LG L+ N D G Y C E++ G V S + V
Sbjct: 2213 GGSLVRQLGTEPTLEITKADPSN----DFGVYRCNVEDNNGLVIGSAFTAVSVGQQDKSH 2268
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V + + A FTC P + W+ E P + AV +G + I
Sbjct: 2269 AQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGD---LP--------SKAVPNG-NKIEI 2316
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAV 416
+ D + S T VC V++ G+ V G VT+ P II S+++ I A
Sbjct: 2317 KEFD-DASAGTYVCK-VSFDGN-VVEG--FVTAQMFVPDTIIQVLLEVSSESPQIGDRAW 2371
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
F C P +I+W EG + + + VT G L+ DL + ++G Y CVA ++ G
Sbjct: 2372 FDCKVTGDPSAVISWTKEGNDDLPPNAQ-VTG-GRLLFTDLKEDNAGVYRCVAKTKAG 2427
Score = 60.5 bits (140), Expect = 7e-09
Identities = 103/435 (23%), Positives = 168/435 (38%), Gaps = 48/435 (11%)
Query: 79 DAGVYWCEATN--SYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+AG Y C AT Y T + + ++ + ++P +G+ C P G
Sbjct: 1194 NAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP-GI 1252
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
P+ + W + G + GN L I ++ AGRY C A N GT +S A
Sbjct: 1253 PDCQITWHREQ----LGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 195 TLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
L++ KP +I D + QT F+C V G+ + W R GG +P G +
Sbjct: 1309 VLEVK-KP-VIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRP-GGAPLPSGVQE- 1364
Query: 252 LDDGSLRLDNVILADEGEYSCEA---ENSVGAVSASGYLTVYDPP------SINLSPNSV 302
G L + + G+Y C A ++ S L + DP + + P +
Sbjct: 1365 -QQGILHIPRASDQEVGQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQ 1423
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V + A+F C G+P + WS + R + + RD + L I+ +
Sbjct: 1424 TVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPNGILERDGF-----------LRIDKSQ 1472
Query: 363 KNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
+D+ C++ GS+ + +L V P + P QT+ + C
Sbjct: 1473 LHDA-GEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQV---DPPVQTVNEGEPSRIRCW 1528
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS-RHGKYVWS 479
P + + G + H R + G L + KSD Y C+A+ + V S
Sbjct: 1529 VPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRTLKSDEDEYICIATDPTTNRPVES 1586
Query: 480 --GALLVDSPINPNI 492
++V SPI P I
Sbjct: 1587 NPARVIVKSPIRPII 1601
Score = 60.1 bits (139), Expect = 9e-09
Identities = 47/175 (26%), Positives = 70/175 (40%), Gaps = 12/175 (6%)
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGS 217
DG ++VI +A + G Y C A N GT + L++ P + P + G
Sbjct: 1842 DGDDIVISEAGDRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGE 1901
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAEN 276
F+C G P P + W G PL V L+ L N G+Y+C A N
Sbjct: 1902 RHQFRCITTGSPTPKITW---TGPNGSPLPHDVTPLEPNILDFSNGRSELNGDYTCTASN 1958
Query: 277 SVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTCT---ATGRPEPTMFW 326
+G S G + + ++ +P + V G + C A G PEP + W
Sbjct: 1959 PIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 2013
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 12/135 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLV 453
P ++ +N +P + C A+ PEP I W + + R T++ GTL
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGTLT 330
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ D D G YTC A + G+ + + +V +P P PPT P
Sbjct: 331 IHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPR---------PQPPQPPTAPPQR 381
Query: 514 NVTDTSVTLSWSQNN 528
DT ++ NN
Sbjct: 382 ASCDTRGAVTPYPNN 396
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 267 EGEYSC-EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+G C + + VG V TV DPP NL V G TC A PEP +
Sbjct: 254 DGTNDCHDGSDEVGCVQP----TVVDPPQTNLQ-----VPRGTTFSLTCKAVAVPEPYIN 304
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W + P + T+ G LTI+D D + C A+N G
Sbjct: 305 WRLNWG-----PVCEPPRCLQTSE-GGYGTLTIHDAQPVD-QGAYTCEAINVKGRVLATP 357
Query: 386 KLTV-TSDDDRPPP 398
V DD RP P
Sbjct: 358 DCIVRVVDDPRPQP 371
Score = 36.7 bits (81), Expect = 0.10
Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 8/142 (5%)
Query: 152 DGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
+GD V GN + I++ AG Y C + G T ++ + +I +
Sbjct: 2300 NGDLPSKAVPNGNKIEIKEFDDASAGTYVCKV-SFDGNVVEGFVTAQMFVPDTIIQVLLE 2358
Query: 211 VVA---QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
V + Q G F C+V GDP + W + GN L + G L ++ +
Sbjct: 2359 VSSESPQIGDRAWFDCKVTGDPSAVISWTKE---GNDDLPPNAQVTGGRLLFTDLKEDNA 2415
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A+ G + L V
Sbjct: 2416 GVYRCVAKTKAGPLQTRTVLNV 2437
Score = 35.5 bits (78), Expect = 0.23
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 208 PEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P + + G V+F+CR P V W R G PL G L ++ V L
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGG----PLPSSAHDSGGRLTINPVQL 106
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV--YDPPSIN 296
+D G Y C ++ + V A L+V Y P ++
Sbjct: 107 SDAGTYICVSDYNGNTVEARATLSVVSYGPQEVS 140
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 200 IKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
++P ++ P+ ++ G++ + C+ P P + WR + G P ++ + G +
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT 328
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSAS 284
L + + D+G Y+CEA N G V A+
Sbjct: 329 LTIHDAQPVDQGAYTCEAINVKGRVLAT 356
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 12 PYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P +++ P ++ V R +L C+A P P I W + V + R + + G +
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINW-RLNWGPVCEPPRCLQTSEGGYGTL 329
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
H D G Y CEA N G
Sbjct: 330 TIHDAQPVDQGAYTCEAINVKG 351
Score = 33.1 bits (72), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 114 PESKQSAQGDTVVLECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
P K+ G V EC S P V W + G L S H GG L I +
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL----PSSAH-DSGGRLTINPVQ 105
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI 198
+DAG Y C++ T E A ATL +
Sbjct: 106 LSDAGTYICVSDYNGNTVE-ARATLSV 131
Score = 32.3 bits (70), Expect = 2.2
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDA 175
Q +G T L C PEP + W+ N + + + +GG L I DA+ D
Sbjct: 282 QVPRGTTFSLTCKAV-AVPEPYINWRLNWGPVC-EPPRCLQTSEGGYGTLTIHDAQPVDQ 339
Query: 176 GRYQCIARNAAG 187
G Y C A N G
Sbjct: 340 GAYTCEAINVKG 351
>L13458-1|AAA28156.1| 2481|Caenorhabditis elegans basement membrane
proteoglycan protein.
Length = 2481
Score = 91.1 bits (216), Expect = 4e-18
Identities = 128/489 (26%), Positives = 195/489 (39%), Gaps = 56/489 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G AP I P + TV + PA C G P ++W + + + IL G F
Sbjct: 1412 GAAPQI--DPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN---GILERDG--F 1464
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE-EFRLEPESKQSAQGDTVV 126
LR ++H DAG Y C +T G+ + S A L+V + + +++P + +G+
Sbjct: 1465 LRIDKSQLH-DAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQTVNEGEPSR 1523
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+ C P G P + + K G+ L +R GNL I ++D Y CIA +
Sbjct: 1524 IRCWVP-GHPNIQLQFVKRGRRPL-PAHARF---SQGNLEIPRTLKSDEDEYICIATDPT 1578
Query: 187 GTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
R ++ +K + I P + GS +C V G P + +RR +G N
Sbjct: 1579 TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVPGHPSVQLTFRRVSGQLNE 1638
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTVY-----DPPSIN-- 296
++G L + L DEG+Y C A + GA S TV+ PP +
Sbjct: 1639 DADE----NNGLLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEAR 1694
Query: 297 ------LSPNSVNVESGNVARFTCTATGRPEPTMFWSVE--GNRTIIFPGMSRDKYHATA 348
++P + + G+ AR CT G P S E + + F G S D+
Sbjct: 1695 PPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFERVDGKGLPF-GSSDDR----- 1748
Query: 349 VFDGVTVLTINDTDKNDSRNTI-VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQ 407
VLTI T D+ + + S N L VT + P P+ T P
Sbjct: 1749 -----GVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTPPRPVAT--PPLL 1801
Query: 408 TLPIKSMAVFPCTAICTPEPIIAWYF-EGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTY 465
++ S A F C A I W F E + H V DG +V+ + + G Y
Sbjct: 1802 SVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEH---VNQDGDDIVISEAGDRNVGEY 1858
Query: 466 TCVASSRHG 474
C A++ G
Sbjct: 1859 VCSATNDFG 1867
Score = 86.6 bits (205), Expect = 9e-17
Identities = 130/527 (24%), Positives = 194/527 (36%), Gaps = 56/527 (10%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAG 64
SG P + P + V +PA C G P I W++ GG L + G
Sbjct: 1221 SGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLP-----HGVYQTG 1275
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L+ ++H AG Y C A N YGT +S A L V +++P + +
Sbjct: 1276 NA--LKIPQSQLHH-AGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQP 1332
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+C P G+ + W + G L G G L I A + G+Y C A +
Sbjct: 1333 ARFKCWVP-GNSNVQLRWSRPGGAPLPSGVQEQQ----GILHIPRASDQEVGQYVCTATD 1387
Query: 185 AAGTRESAIATLKIHIK----PYLITGPE-DVVAQT---GSSVTFQCRVGGDPLPDVLWR 236
+ ++++I+ P P+ D QT F+C V G P + W
Sbjct: 1388 PSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWS 1447
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--VSASGYLTVYDPPS 294
R G PL + DG LR+D L D GEY C + G+ +S L V P +
Sbjct: 1448 RKDG---RPLPNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQA 1504
Query: 295 I--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I + P V G +R C G P + + G R + P +R
Sbjct: 1505 IQPQVDPPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPL--PAHARFSQGN------ 1556
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I T K+D + +C A + + V PII P+ QT+P
Sbjct: 1557 ---LEIPRTLKSD-EDEYICIATDPTTNRPVESNPARVIVKSPIRPII--DPAEQTVPEG 1610
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
S F P + F + N + N+G L ++ + +D G Y C A
Sbjct: 1611 S--PFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-ENNGLLAVQRAELTDEGDYICTARDP 1667
Query: 473 HGKYVWSGALLVDSPINPNIHFFRAADVSSLPG-PPTKPITHNVTDT 518
+GA + +P +H AA + PP P+ T T
Sbjct: 1668 D-----TGAPIDSTP--ATVHVTNAAAPPQVEARPPQHPVITPQTQT 1707
Score = 71.7 bits (168), Expect = 3e-12
Identities = 85/374 (22%), Positives = 142/374 (37%), Gaps = 31/374 (8%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170
+EP+ + + GD V C + E +V W K G+ L +++ + G LV++
Sbjct: 1134 MEPKRQIALPGDRVHWICQVTGYTTEKIHVEWTKVGEMSL-PPNAKAY---DGYLVLKGV 1189
Query: 171 RQTDAGRYQCIARNAAG-TRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVG 226
+AG+Y+C A + A+ T+ I P + P +V G F+C V
Sbjct: 1190 EAENAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP 1249
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
G P + W R GG +P G + +L++ L G Y C A N G +
Sbjct: 1250 GIPDCQITWHREQLGGPLPHGVYQT--GNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1307
Query: 287 LTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
+ P I + P V+ ARF C G + WS G +
Sbjct: 1308 VLEVKKPVIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRPGGAPL---------- 1357
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----II 400
+ V + +L I + VC+A + + ++ ++ + + D PP
Sbjct: 1358 -PSGVQEQQGILHIPRASDQEV-GQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAP 1415
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
P NQT+ + A F C P + W + + N + DG L +
Sbjct: 1416 QIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN--GILERDGFLRIDKSQLH 1473
Query: 461 DSGTYTCVASSRHG 474
D+G Y C ++ G
Sbjct: 1474 DAGEYECTSTEPDG 1487
Score = 71.7 bits (168), Expect = 3e-12
Identities = 112/483 (23%), Positives = 181/483 (37%), Gaps = 52/483 (10%)
Query: 15 IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHG 74
++ P+ TV +P+ + C G P+ +++ K G + R G L R
Sbjct: 1509 VDPPVQ-TVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRT--- 1562
Query: 75 RVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVVLECLPP 132
+ SD Y C AT+ T R + +++ R ++P + +G + C P
Sbjct: 1563 -LKSDEDEYICIATDPT-TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVP 1620
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN--AAGTRE 190
G P + +++ L D D + G L +Q A TD G Y C AR+ +
Sbjct: 1621 -GHPSVQLTFRRVSGQLNEDADE-----NNGLLAVQRAELTDEGDYICTARDPDTGAPID 1674
Query: 191 SAIATL---------KIHIKP--YLITGPEDVVAQTGSSVTFQCRVGGDP--LPDVLWRR 237
S AT+ ++ +P + + P+ G QC V G+P + + R
Sbjct: 1675 STPATVHVTNAAAPPQVEARPPQHPVITPQTQTIPEGDPARIQCTVPGNPSAAQHLSFER 1734
Query: 238 SAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSC--EAENSVGAVSASGYLTVYD---P 292
G G +P G D G L + + L D GEY C ENS + L V P
Sbjct: 1735 VDGKG-LPFGSSD--DRGVLTIPSTQLQDAGEYVCLYSPENSPPVKTNPSTLNVTPEGTP 1791
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P +P ++V G+ ARF C A + W + +++D D
Sbjct: 1792 PRPVATPPLLSVAPGSPARFNCVAHSDTPARIRWGFREENGPLPEHVNQDG-------DD 1844
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
+ + D + + VCSA N G+ V + + +D+ PP P
Sbjct: 1845 IVISEAGDRNVGE----YVCSATNDFGTG-VADPVRLEVTEDQEPPTAVVEPRTWNGKPG 1899
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
F C +P P I W + + H L + +G YTC AS+
Sbjct: 1900 ERHQFRCITTGSPTPKITWTGPNGSPLP-HDVTPLEPNILDFSNGRSELNGDYTCTASNP 1958
Query: 473 HGK 475
G+
Sbjct: 1959 IGE 1961
Score = 70.1 bits (164), Expect = 9e-12
Identities = 86/328 (26%), Positives = 129/328 (39%), Gaps = 32/328 (9%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G P + P ++VA PA NC A IRW G + + G
Sbjct: 1789 GTPPRPVATPPLLSVAPGSPARFNCVAHSDTPARIRW---GFREENGPLPEHVNQDGDDI 1845
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR--LEPESKQSAQGDTVV 126
+ + G + G Y C ATN +GT + L V +E +EP + G+
Sbjct: 1846 VISEAG--DRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGERHQ 1903
Query: 127 LECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
C+ GSP P + W NG L D + ++ L + R G Y C A N
Sbjct: 1904 FRCITT-GSPTPKITWTGPNGSPLPHD----VTPLEPNILDFSNGRSELNGDYTCTASNP 1958
Query: 186 AGTRESAIATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRV---GGDPLPDVLWRR 237
G A ++I P L GP+ +V G + +C GDP P+V W
Sbjct: 1959 IG---EASDHGNVNIGPSLTVKTNPPGPKLIVT-VGEPLQVKCEAFGAPGDPEPEVEWLH 2014
Query: 238 SAGG--GNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
G G++P V + + +R NV L + G Y+C+ ++ + + Y+ V +P
Sbjct: 2015 DPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHATATKNIYIEVVEPSR 2074
Query: 295 IN----LSPNSVNVESGNVARFTCTATG 318
I L +S + G CTATG
Sbjct: 2075 IATVSILGGSSQWFDQGEKGELICTATG 2102
Score = 62.9 bits (146), Expect = 1e-09
Identities = 123/478 (25%), Positives = 185/478 (38%), Gaps = 58/478 (12%)
Query: 19 LDVTVARHQPATLNCRAGGSPS---PAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHG 74
L VTV +P + C A G+P P + W D P F+R H
Sbjct: 1985 LIVTVG--EPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIR--HP 2040
Query: 75 RVH-SDAGVYWCEATNSYGTARSRNATLHVAV---LREEFRLEPESKQSAQGDTVVLECL 130
V +AGVY C+ ++++ TA ++N + V + L S+ QG+ L C
Sbjct: 2041 NVGLGNAGVYTCKGSSAHATA-TKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICT 2099
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--------IA 182
S + W+K L D + + G L + + AG Y+C IA
Sbjct: 2100 ATGSSLVDRLEWEKVDDQLPTDVEEHN---EPGLLHFPSFKNSYAGEYRCNGYRNNEIIA 2156
Query: 183 RNAAGTRESAIAT--LKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239
A SA A K+ I+P P V G ++ +C V G + W
Sbjct: 2157 SAAVHVHSSANADDEPKVEIEP-----PRVRVVSQGDNIVLKCSVQGAENGEHFKWALLR 2211
Query: 240 GGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
GG + LG L+ N D G Y C E++ G V S + V
Sbjct: 2212 GGSLVRQLGTEPTLEITKADPSN----DFGVYRCNVEDNNGLVIGSAFTAVSVGQQDKSH 2267
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V + + A FTC P + W+ E P + AV +G + I
Sbjct: 2268 AQIVKFDDKSDASFTCPIYSVPGSKVDWTYENGD---LP--------SKAVPNG-NKIEI 2315
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITN--GPSNQTLPIKSMAV 416
+ D + S T VC V++ G+ V G VT+ P II S+++ I A
Sbjct: 2316 KEFD-DASAGTYVCK-VSFDGN-VVEG--FVTAQMFVPDTIIQVLLEVSSESPQIGDRAW 2370
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
F C P +I+W EG + + + VT G L+ DL + ++G Y CVA ++ G
Sbjct: 2371 FDCKVTGDPSAVISWTKEGNDDLPPNAQ-VTG-GRLLFTDLKEDNAGVYRCVAKTKAG 2426
Score = 60.5 bits (140), Expect = 7e-09
Identities = 103/435 (23%), Positives = 168/435 (38%), Gaps = 48/435 (11%)
Query: 79 DAGVYWCEATN--SYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+AG Y C AT Y T + + ++ + ++P +G+ C P G
Sbjct: 1193 NAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP-GI 1251
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
P+ + W + G + GN L I ++ AGRY C A N GT +S A
Sbjct: 1252 PDCQITWHREQ----LGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1307
Query: 195 TLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
L++ KP +I D + QT F+C V G+ + W R GG +P G +
Sbjct: 1308 VLEVK-KP-VIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRP-GGAPLPSGVQE- 1363
Query: 252 LDDGSLRLDNVILADEGEYSCEA---ENSVGAVSASGYLTVYDPP------SINLSPNSV 302
G L + + G+Y C A ++ S L + DP + + P +
Sbjct: 1364 -QQGILHIPRASDQEVGQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQ 1422
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V + A+F C G+P + WS + R + + RD + L I+ +
Sbjct: 1423 TVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPNGILERDGF-----------LRIDKSQ 1471
Query: 363 KNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
+D+ C++ GS+ + +L V P + P QT+ + C
Sbjct: 1472 LHDA-GEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQV---DPPVQTVNEGEPSRIRCW 1527
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS-RHGKYVWS 479
P + + G + H R + G L + KSD Y C+A+ + V S
Sbjct: 1528 VPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRTLKSDEDEYICIATDPTTNRPVES 1585
Query: 480 --GALLVDSPINPNI 492
++V SPI P I
Sbjct: 1586 NPARVIVKSPIRPII 1600
Score = 60.1 bits (139), Expect = 9e-09
Identities = 47/175 (26%), Positives = 70/175 (40%), Gaps = 12/175 (6%)
Query: 161 DGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGS 217
DG ++VI +A + G Y C A N GT + L++ P + P + G
Sbjct: 1841 DGDDIVISEAGDRNVGEYVCSATNDFGTGVADPVRLEVTEDQEPPTAVVEPRTWNGKPGE 1900
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR-VKVLDDGSLRLDNVILADEGEYSCEAEN 276
F+C G P P + W G PL V L+ L N G+Y+C A N
Sbjct: 1901 RHQFRCITTGSPTPKITW---TGPNGSPLPHDVTPLEPNILDFSNGRSELNGDYTCTASN 1957
Query: 277 SVGAVSASGYLTVYDPPSINLSP--NSVNVESGNVARFTCT---ATGRPEPTMFW 326
+G S G + + ++ +P + V G + C A G PEP + W
Sbjct: 1958 PIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVGEPLQVKCEAFGAPGDPEPEVEW 2012
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 12/135 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLV 453
P ++ +N +P + C A+ PEP I W + + R T++ GTL
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGTLT 330
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ D D G YTC A + G+ + + +V +P P PPT P
Sbjct: 331 IHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPR---------PQPPQPPTAPPQR 381
Query: 514 NVTDTSVTLSWSQNN 528
DT ++ NN
Sbjct: 382 ASCDTRGAVTPYPNN 396
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 267 EGEYSC-EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+G C + + VG V TV DPP NL V G TC A PEP +
Sbjct: 254 DGTNDCHDGSDEVGCVQP----TVVDPPQTNLQ-----VPRGTTFSLTCKAVAVPEPYIN 304
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W + P + T+ G LTI+D D + C A+N G
Sbjct: 305 WRLNWG-----PVCEPPRCLQTSE-GGYGTLTIHDAQPVD-QGAYTCEAINVKGRVLATP 357
Query: 386 KLTV-TSDDDRPPP 398
V DD RP P
Sbjct: 358 DCIVRVVDDPRPQP 371
Score = 36.7 bits (81), Expect = 0.10
Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 8/142 (5%)
Query: 152 DGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
+GD V GN + I++ AG Y C + G T ++ + +I +
Sbjct: 2299 NGDLPSKAVPNGNKIEIKEFDDASAGTYVCKV-SFDGNVVEGFVTAQMFVPDTIIQVLLE 2357
Query: 211 VVA---QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
V + Q G F C+V GDP + W + GN L + G L ++ +
Sbjct: 2358 VSSESPQIGDRAWFDCKVTGDPSAVISWTKE---GNDDLPPNAQVTGGRLLFTDLKEDNA 2414
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A+ G + L V
Sbjct: 2415 GVYRCVAKTKAGPLQTRTVLNV 2436
Score = 35.5 bits (78), Expect = 0.23
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 208 PEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P + + G V+F+CR P V W R G PL G L ++ V L
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGG----PLPSSAHDSGGRLTINPVQL 106
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV--YDPPSIN 296
+D G Y C ++ + V A L+V Y P ++
Sbjct: 107 SDAGTYICVSDYNGNTVEARATLSVVSYGPQEVS 140
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 200 IKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
++P ++ P+ ++ G++ + C+ P P + WR + G P ++ + G +
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT 328
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSAS 284
L + + D+G Y+CEA N G V A+
Sbjct: 329 LTIHDAQPVDQGAYTCEAINVKGRVLAT 356
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 12 PYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P +++ P ++ V R +L C+A P P I W + V + R + + G +
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINW-RLNWGPVCEPPRCLQTSEGGYGTL 329
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
H D G Y CEA N G
Sbjct: 330 TIHDAQPVDQGAYTCEAINVKG 351
Score = 33.1 bits (72), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 114 PESKQSAQGDTVVLECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
P K+ G V EC S P V W + G L S H GG L I +
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL----PSSAH-DSGGRLTINPVQ 105
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI 198
+DAG Y C++ T E A ATL +
Sbjct: 106 LSDAGTYICVSDYNGNTVE-ARATLSV 131
Score = 32.3 bits (70), Expect = 2.2
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDA 175
Q +G T L C PEP + W+ N + + + +GG L I DA+ D
Sbjct: 282 QVPRGTTFSLTCKAV-AVPEPYINWRLNWGPVC-EPPRCLQTSEGGYGTLTIHDAQPVDQ 339
Query: 176 GRYQCIARNAAG 187
G Y C A N G
Sbjct: 340 GAYTCEAINVKG 351
>U49830-6|AAK31481.1| 964|Caenorhabditis elegans Neuronal igcam
protein 6, isoform a protein.
Length = 964
Score = 89.8 bits (213), Expect = 1e-17
Identities = 89/328 (27%), Positives = 143/328 (43%), Gaps = 26/328 (7%)
Query: 31 LNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
L C A SP P +W + G + + +H I G + + + + DAG Y C A N
Sbjct: 138 LECFAYASPLPQYKWSRVDGKPIPARSH--ISNYGRVLKIEKVN---YGDAGKYKCVAMN 192
Query: 90 SYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ- 147
++G+A +HV + L+ + V ECL +V W K+ +
Sbjct: 193 AFGSAAGE---VHVKLRAPPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKP 249
Query: 148 --TLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAG-TRESAIATLKIHIKPY 203
LL + R L +D L ++ A +TD+G YQC+A N G + SA+ T+K +
Sbjct: 250 IVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVF 309
Query: 204 LITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDGSLRLDN 261
V A GS+V+ C P W AGG +P GR++ ++G + ++
Sbjct: 310 PPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKW-ADAGGSKLPQKGRIRD-EEGVISIEK 367
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA---RFTCTATG 318
V+ D G + C A N +G A L V + PSI N ++ E+ N++ TC +
Sbjct: 368 VLHEDAGLFFCTAHNKLGKAHAQVQLIVVNKPSI--KTNFLDEETVNMSCEVELTCENSA 425
Query: 319 R-PEPTMFWSVEGNRTIIFPGMSRDKYH 345
PE W + +P + + K H
Sbjct: 426 ECPEALFEWKINDRPAKEYPSL-KSKVH 452
Score = 83.8 bits (198), Expect = 7e-16
Identities = 87/323 (26%), Positives = 137/323 (42%), Gaps = 34/323 (10%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQ 179
GD++ LEC SP P W + +G+ + +R H+ + G ++ I+ DAG+Y+
Sbjct: 133 GDSIYLECFA-YASPLPQYKWSRVDGKPI----PARSHISNYGRVLKIEKVNYGDAGKYK 187
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG-DPLPDVLWRRS 238
C+A NA G+ + +K+ P ++ G D + T S+V+F+C + D V W +
Sbjct: 188 CVAMNAFGSAAGEVH-VKLRAPPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKD 246
Query: 239 AGGGN---MPLGRVKVL--DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
A +P + K L D L L D G Y C A N VG+ S+S LTV D
Sbjct: 247 AKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSA 306
Query: 294 SI---NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
+ N V G+ C P W+ G + G RD+
Sbjct: 307 PVFPPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKWADAGGSKLPQKGRIRDE------- 359
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
+G V++I D+ C+A N G + + +L V + P I TN +T+
Sbjct: 360 EG--VISIEKVLHEDA-GLFFCTAHNKLGKAHAQVQLIVVN----KPSIKTNFLDEETVN 412
Query: 411 IKSMAVFPC--TAICTPEPIIAW 431
+ C +A C PE + W
Sbjct: 413 MSCEVELTCENSAEC-PEALFEW 434
Score = 64.1 bits (149), Expect = 6e-10
Identities = 70/272 (25%), Positives = 110/272 (40%), Gaps = 16/272 (5%)
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILAD 266
PED + G S+ +C PLP W R G +P R + + G L+++ V D
Sbjct: 127 PED--PKVGDSIYLECFAYASPLPQYKWSR-VDGKPIP-ARSHISNYGRVLKIEKVNYGD 182
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTM 324
G+Y C A N+ G+ + ++ + PPSI L V ES NV+ F C + +
Sbjct: 183 AGKYKCVAMNAFGSAAGEVHVKLRAPPSILQGLHDRLVPTES-NVS-FECLLSNADSYSS 240
Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
+ + I+ + +K + V L + D+ DS C A N GSS
Sbjct: 241 VEWFKDAKPIVPLLLPAEKRKRLKIDHNV--LHLKFADETDS-GVYQCVASNDVGSSSSS 297
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHR 443
LTV D P N S + V PC +P W G + +
Sbjct: 298 ALLTVK---DSAPVFPPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKWADAGGSKLPQKG 354
Query: 444 RNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
R +G + ++ + D+G + C A ++ GK
Sbjct: 355 RIRDEEGVISIEKVLHEDAGLFFCTAHNKLGK 386
Score = 41.5 bits (93), Expect = 0.004
Identities = 40/145 (27%), Positives = 65/145 (44%), Gaps = 15/145 (10%)
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
VL I + D+ C A+N GS+ G++ V R PP I G ++ +P +S
Sbjct: 172 VLKIEKVNYGDA-GKYKCVAMNAFGSA--AGEVHVKL---RAPPSILQGLHDRLVPTESN 225
Query: 415 AVFPCT-AICTPEPIIAWYFEGEALI------QNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
F C + + W+ + + ++ + +R + L LK D++DSG Y C
Sbjct: 226 VSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQC 285
Query: 468 VASSRHGKYVWSGALLV--DSPINP 490
VAS+ G S L V +P+ P
Sbjct: 286 VASNDVGSSSSSALLTVKDSAPVFP 310
>U49830-5|AAK31482.1| 1227|Caenorhabditis elegans Neuronal igcam
protein 6, isoform b protein.
Length = 1227
Score = 89.8 bits (213), Expect = 1e-17
Identities = 89/328 (27%), Positives = 143/328 (43%), Gaps = 26/328 (7%)
Query: 31 LNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
L C A SP P +W + G + + +H I G + + + + DAG Y C A N
Sbjct: 401 LECFAYASPLPQYKWSRVDGKPIPARSH--ISNYGRVLKIEKVN---YGDAGKYKCVAMN 455
Query: 90 SYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ- 147
++G+A +HV + L+ + V ECL +V W K+ +
Sbjct: 456 AFGSAAGE---VHVKLRAPPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKP 512
Query: 148 --TLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAG-TRESAIATLKIHIKPY 203
LL + R L +D L ++ A +TD+G YQC+A N G + SA+ T+K +
Sbjct: 513 IVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVF 572
Query: 204 LITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDGSLRLDN 261
V A GS+V+ C P W AGG +P GR++ ++G + ++
Sbjct: 573 PPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKW-ADAGGSKLPQKGRIRD-EEGVISIEK 630
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA---RFTCTATG 318
V+ D G + C A N +G A L V + PSI N ++ E+ N++ TC +
Sbjct: 631 VLHEDAGLFFCTAHNKLGKAHAQVQLIVVNKPSI--KTNFLDEETVNMSCEVELTCENSA 688
Query: 319 R-PEPTMFWSVEGNRTIIFPGMSRDKYH 345
PE W + +P + + K H
Sbjct: 689 ECPEALFEWKINDRPAKEYPSL-KSKVH 715
Score = 85.8 bits (203), Expect = 2e-16
Identities = 115/470 (24%), Positives = 184/470 (39%), Gaps = 43/470 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLFFLRATHGRVHSDAGVYWCEAT 88
L C G+P P + WYK V V+S + ++ L +GG + A+ +S + C A
Sbjct: 198 LPCTVQGNPKPTVAWYKNDVEVLSPSMSNVSYLLSGGNLLVPASSTLAYSS---FHCTAR 254
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQ 147
NS G RS L + + + FR S L+C P P+ Y W
Sbjct: 255 NSLGEVRSPPILLKPSFI-DPFRPHRLDVYSLATGGAKLDCDAPAHQPKSLTYSWLYGSS 313
Query: 148 T--LLFDGDSRMHLVDG----GNLVIQD---------ARQTDAGRYQCIARNAAGTRESA 192
T +L + + +DG + +D T +G Y R + T +
Sbjct: 314 TDRILSQNERKFISLDGTLFFSYVTAEDEDSYACSLSVYSTQSGHYGPFFRLISSTPKLV 373
Query: 193 IATLKIHI---KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
+T + +P + PED + G S+ +C PLP W R G +P R
Sbjct: 374 NSTFPPKLDSTQPQIF--PED--PKVGDSIYLECFAYASPLPQYKWSR-VDGKPIP-ARS 427
Query: 250 KVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVES 306
+ + G L+++ V D G+Y C A N+ G+ + ++ + PPSI L V ES
Sbjct: 428 HISNYGRVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLRAPPSILQGLHDRLVPTES 487
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
NV+ F C + + + + I+ + +K + V L + D+ DS
Sbjct: 488 -NVS-FECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNV--LHLKFADETDS 543
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTP 425
C A N GSS LTV D P N S + V PC +P
Sbjct: 544 -GVYQCVASNDVGSSSSSALLTVK---DSAPVFPPNAMSRKVFAAFGSTVSIPCIFEASP 599
Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W G + + R +G + ++ + D+G + C A ++ GK
Sbjct: 600 RFHGKWADAGGSKLPQKGRIRDEEGVISIEKVLHEDAGLFFCTAHNKLGK 649
Score = 83.8 bits (198), Expect = 7e-16
Identities = 87/323 (26%), Positives = 137/323 (42%), Gaps = 34/323 (10%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQ 179
GD++ LEC SP P W + +G+ + +R H+ + G ++ I+ DAG+Y+
Sbjct: 396 GDSIYLECFA-YASPLPQYKWSRVDGKPI----PARSHISNYGRVLKIEKVNYGDAGKYK 450
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG-DPLPDVLWRRS 238
C+A NA G+ + +K+ P ++ G D + T S+V+F+C + D V W +
Sbjct: 451 CVAMNAFGSAAGEVH-VKLRAPPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKD 509
Query: 239 AGGGN---MPLGRVKVL--DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
A +P + K L D L L D G Y C A N VG+ S+S LTV D
Sbjct: 510 AKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSA 569
Query: 294 SI---NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
+ N V G+ C P W+ G + G RD+
Sbjct: 570 PVFPPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKWADAGGSKLPQKGRIRDE------- 622
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
+G V++I D+ C+A N G + + +L V + P I TN +T+
Sbjct: 623 EG--VISIEKVLHEDA-GLFFCTAHNKLGKAHAQVQLIVVN----KPSIKTNFLDEETVN 675
Query: 411 IKSMAVFPC--TAICTPEPIIAW 431
+ C +A C PE + W
Sbjct: 676 MSCEVELTCENSAEC-PEALFEW 697
Score = 62.9 bits (146), Expect = 1e-09
Identities = 94/398 (23%), Positives = 149/398 (37%), Gaps = 48/398 (12%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCI 181
D + L C +G+P+P V W KN +L S + +L+ GGNL++ + + C
Sbjct: 194 DYIALPCTV-QGNPKPTVAWYKNDVEVLSPSMSNVSYLLSGGNLLVPASSTLAYSSFHCT 252
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
ARN+ G S LK DV + C + + G
Sbjct: 253 ARNSLGEVRSPPILLKPSFIDPFRPHRLDVYSLATGGAKLDCDAPAHQPKSLTYSWLYGS 312
Query: 242 GN---MPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291
+ K + DG+L V DE Y+C SV + + Y +
Sbjct: 313 STDRILSQNERKFISLDGTLFFSYVTAEDEDSYACSL--SVYSTQSGHYGPFFRLISSTP 370
Query: 292 -------PPSINLSPNSVNVES---GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
PP ++ + + E G+ C A P P WS + I P S
Sbjct: 371 KLVNSTFPPKLDSTQPQIFPEDPKVGDSIYLECFAYASPLPQYKWSRVDGKPI--PARSH 428
Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
+ VL I + D+ C A+N GS+ G++ V R PP I
Sbjct: 429 ISNYG-------RVLKIEKVNYGDA-GKYKCVAMNAFGSA--AGEVHVKL---RAPPSIL 475
Query: 402 NGPSNQTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALI------QNHRRNVTNDGTLVL 454
G ++ +P +S F C + + W+ + + ++ + +R + L L
Sbjct: 476 QGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNVLHL 535
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPINP 490
K D++DSG Y CVAS+ G S L V +P+ P
Sbjct: 536 KFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVFP 573
>U49830-4|AAU20850.1| 1196|Caenorhabditis elegans Neuronal igcam
protein 6, isoform d protein.
Length = 1196
Score = 89.8 bits (213), Expect = 1e-17
Identities = 89/328 (27%), Positives = 143/328 (43%), Gaps = 26/328 (7%)
Query: 31 LNCRAGGSPSPAIRWYK-GGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATN 89
L C A SP P +W + G + + +H I G + + + + DAG Y C A N
Sbjct: 370 LECFAYASPLPQYKWSRVDGKPIPARSH--ISNYGRVLKIEKVN---YGDAGKYKCVAMN 424
Query: 90 SYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ- 147
++G+A +HV + L+ + V ECL +V W K+ +
Sbjct: 425 AFGSAAGE---VHVKLRAPPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKP 481
Query: 148 --TLLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQCIARNAAG-TRESAIATLKIHIKPY 203
LL + R L +D L ++ A +TD+G YQC+A N G + SA+ T+K +
Sbjct: 482 IVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVF 541
Query: 204 LITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKVLDDGSLRLDN 261
V A GS+V+ C P W AGG +P GR++ ++G + ++
Sbjct: 542 PPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKW-ADAGGSKLPQKGRIRD-EEGVISIEK 599
Query: 262 VILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVA---RFTCTATG 318
V+ D G + C A N +G A L V + PSI N ++ E+ N++ TC +
Sbjct: 600 VLHEDAGLFFCTAHNKLGKAHAQVQLIVVNKPSI--KTNFLDEETVNMSCEVELTCENSA 657
Query: 319 R-PEPTMFWSVEGNRTIIFPGMSRDKYH 345
PE W + +P + + K H
Sbjct: 658 ECPEALFEWKINDRPAKEYPSL-KSKVH 684
Score = 85.8 bits (203), Expect = 2e-16
Identities = 115/470 (24%), Positives = 184/470 (39%), Gaps = 43/470 (9%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSI--LPAGGLFFLRATHGRVHSDAGVYWCEAT 88
L C G+P P + WYK V V+S + ++ L +GG + A+ +S + C A
Sbjct: 167 LPCTVQGNPKPTVAWYKNDVEVLSPSMSNVSYLLSGGNLLVPASSTLAYSS---FHCTAR 223
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQ 147
NS G RS L + + + FR S L+C P P+ Y W
Sbjct: 224 NSLGEVRSPPILLKPSFI-DPFRPHRLDVYSLATGGAKLDCDAPAHQPKSLTYSWLYGSS 282
Query: 148 T--LLFDGDSRMHLVDG----GNLVIQD---------ARQTDAGRYQCIARNAAGTRESA 192
T +L + + +DG + +D T +G Y R + T +
Sbjct: 283 TDRILSQNERKFISLDGTLFFSYVTAEDEDSYACSLSVYSTQSGHYGPFFRLISSTPKLV 342
Query: 193 IATLKIHI---KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV 249
+T + +P + PED + G S+ +C PLP W R G +P R
Sbjct: 343 NSTFPPKLDSTQPQIF--PED--PKVGDSIYLECFAYASPLPQYKWSR-VDGKPIP-ARS 396
Query: 250 KVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI--NLSPNSVNVES 306
+ + G L+++ V D G+Y C A N+ G+ + ++ + PPSI L V ES
Sbjct: 397 HISNYGRVLKIEKVNYGDAGKYKCVAMNAFGSAAGEVHVKLRAPPSILQGLHDRLVPTES 456
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
NV+ F C + + + + I+ + +K + V L + D+ DS
Sbjct: 457 -NVS-FECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNV--LHLKFADETDS 512
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTP 425
C A N GSS LTV D P N S + V PC +P
Sbjct: 513 -GVYQCVASNDVGSSSSSALLTVK---DSAPVFPPNAMSRKVFAAFGSTVSIPCIFEASP 568
Query: 426 EPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
W G + + R +G + ++ + D+G + C A ++ GK
Sbjct: 569 RFHGKWADAGGSKLPQKGRIRDEEGVISIEKVLHEDAGLFFCTAHNKLGK 618
Score = 83.8 bits (198), Expect = 7e-16
Identities = 87/323 (26%), Positives = 137/323 (42%), Gaps = 34/323 (10%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKK-NGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQ 179
GD++ LEC SP P W + +G+ + +R H+ + G ++ I+ DAG+Y+
Sbjct: 365 GDSIYLECFA-YASPLPQYKWSRVDGKPI----PARSHISNYGRVLKIEKVNYGDAGKYK 419
Query: 180 CIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG-DPLPDVLWRRS 238
C+A NA G+ + +K+ P ++ G D + T S+V+F+C + D V W +
Sbjct: 420 CVAMNAFGSAAGEVH-VKLRAPPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKD 478
Query: 239 AGGGN---MPLGRVKVL--DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
A +P + K L D L L D G Y C A N VG+ S+S LTV D
Sbjct: 479 AKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSA 538
Query: 294 SI---NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVF 350
+ N V G+ C P W+ G + G RD+
Sbjct: 539 PVFPPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKWADAGGSKLPQKGRIRDE------- 591
Query: 351 DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLP 410
+G V++I D+ C+A N G + + +L V + P I TN +T+
Sbjct: 592 EG--VISIEKVLHEDA-GLFFCTAHNKLGKAHAQVQLIVVN----KPSIKTNFLDEETVN 644
Query: 411 IKSMAVFPC--TAICTPEPIIAW 431
+ C +A C PE + W
Sbjct: 645 MSCEVELTCENSAEC-PEALFEW 666
Score = 62.9 bits (146), Expect = 1e-09
Identities = 94/398 (23%), Positives = 149/398 (37%), Gaps = 48/398 (12%)
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM-HLVDGGNLVIQDARQTDAGRYQCI 181
D + L C +G+P+P V W KN +L S + +L+ GGNL++ + + C
Sbjct: 163 DYIALPCTV-QGNPKPTVAWYKNDVEVLSPSMSNVSYLLSGGNLLVPASSTLAYSSFHCT 221
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
ARN+ G S LK DV + C + + G
Sbjct: 222 ARNSLGEVRSPPILLKPSFIDPFRPHRLDVYSLATGGAKLDCDAPAHQPKSLTYSWLYGS 281
Query: 242 GN---MPLGRVKVLD-DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD------ 291
+ K + DG+L V DE Y+C SV + + Y +
Sbjct: 282 STDRILSQNERKFISLDGTLFFSYVTAEDEDSYACSL--SVYSTQSGHYGPFFRLISSTP 339
Query: 292 -------PPSINLSPNSVNVES---GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
PP ++ + + E G+ C A P P WS + I P S
Sbjct: 340 KLVNSTFPPKLDSTQPQIFPEDPKVGDSIYLECFAYASPLPQYKWSRVDGKPI--PARSH 397
Query: 342 DKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIIT 401
+ VL I + D+ C A+N GS+ G++ V R PP I
Sbjct: 398 ISNYG-------RVLKIEKVNYGDA-GKYKCVAMNAFGSA--AGEVHVKL---RAPPSIL 444
Query: 402 NGPSNQTLPIKSMAVFPC-TAICTPEPIIAWYFEGEALI------QNHRRNVTNDGTLVL 454
G ++ +P +S F C + + W+ + + ++ + +R + L L
Sbjct: 445 QGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNVLHL 504
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPINP 490
K D++DSG Y CVAS+ G S L V +P+ P
Sbjct: 505 KFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVFP 542
>U50067-4|AAA93439.3| 1144|Caenorhabditis elegans Sensory axon
guidance protein 7,isoform a protein.
Length = 1144
Score = 87.8 bits (208), Expect = 4e-17
Identities = 87/317 (27%), Positives = 126/317 (39%), Gaps = 28/317 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF--FLRATHGRVHSD-AGVYWCEA 87
L+C G P+P RW+ G + D+ AG F + + V D AG Y C
Sbjct: 89 LHCFFSGYPAPKPRWFHNGREISEDSDA----AGFRFESYGKTLVFNVTQDKAGKYDCRF 144
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
R+ N + A P + +++G+ V+ +C G P P V + KNG
Sbjct: 145 ATQQDIDRTFNVVVEAAPYWPLG--PPPNTNTSEGEKVIFDCTT-YGKPTPKVTFYKNGV 201
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGR-----YQCIARNAAGTRESAIATLKIHIKP 202
+ D R +L++G L I D ++ G+ YQC + N G + + KP
Sbjct: 202 EIESQKDDR-YLIEGTRLTIFDVKKGTYGKGDNAVYQCKSENKHGWLWTNFYLNLLAFKP 260
Query: 203 YLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRR----SAGGGNMPLGRVKVLDDGS 256
L+ P E+V A G VT +C+ P V W + G +P V G
Sbjct: 261 QLLIDPGKEEVEAVAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGV---GK 317
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTC- 314
L V A+EGEY C N G + L V P + P V +G R C
Sbjct: 318 LVFSEVTAAEEGEYECIGTNKYGQATGLITLKVRKPTIVQPFPRVEEVRMAGEEMRLACD 377
Query: 315 -TATGRPEPTMFWSVEG 330
TA + E W V+G
Sbjct: 378 ATADNQLEVKYEWLVDG 394
Score = 74.5 bits (175), Expect = 4e-13
Identities = 71/297 (23%), Positives = 119/297 (40%), Gaps = 20/297 (6%)
Query: 11 APYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
APY + P + + + +C G P+P + +YK GV + S L G +
Sbjct: 161 APYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTI 220
Query: 70 ----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP--ESKQSAQGD 123
+ T+G+ D VY C++ N +G + N L++ + + ++P E ++ G
Sbjct: 221 FDVKKGTYGK--GDNAVYQCKSENKHGWLWT-NFYLNLLAFKPQLLIDPGKEEVEAVAGK 277
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
V LEC SP V W+ + G LV + + G Y+CI
Sbjct: 278 KVTLEC-KFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGT 336
Query: 184 NAAGTRESAIATLKIHIKPYLITG-PE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
N G + + + TLK+ KP ++ P + V G + C D +V + G
Sbjct: 337 NKYG-QATGLITLKVR-KPTIVQPFPRVEEVRMAGEEMRLACDATADNQLEVKYEWLVDG 394
Query: 242 GNMPLGRV-----KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
++P R+ K+ DD SL + N D +Y C + V + D P
Sbjct: 395 KSLPEDRISSGHYKIDDDHSLVISNPTQDDTAKYKCVVSTKLDQVEKEIKIQFKDVP 451
Score = 39.9 bits (89), Expect = 0.011
Identities = 58/287 (20%), Positives = 98/287 (34%), Gaps = 24/287 (8%)
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGE 269
+A G+ C G P P W + + + G + NV G+
Sbjct: 80 IALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGKTLVFNVTQDKAGK 139
Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSV 328
Y C + + + V P L P + N G F CT G+P P + +
Sbjct: 140 YDCRFATQQD-IDRTFNVVVEAAPYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYK 198
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND---SRNTIV-CSAVNYAGSSFVR 384
G + D+Y + +G T LTI D K N + C + N G +
Sbjct: 199 NG---VEIESQKDDRY----LIEG-TRLTIFDVKKGTYGKGDNAVYQCKSENKHGWLWTN 250
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
L + + +P +I G C +P + W E + +
Sbjct: 251 FYLNLLAF--KPQLLIDPGKEEVEAVAGKKVTLECKFFASPNAAVKW--EAPMISGSKGN 306
Query: 445 NVTND----GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ D G LV ++ ++ G Y C+ ++++G+ L V P
Sbjct: 307 QIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQATGLITLKVRKP 353
Score = 33.9 bits (74), Expect = 0.71
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 725 QTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
+T + VP P + + + TTV L W+ + Q NG TGY + W+D
Sbjct: 672 RTGEGVPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGNFTGYKITY-WVD 721
>U50067-3|AAZ32801.1| 1147|Caenorhabditis elegans Sensory axon
guidance protein 7,isoform d protein.
Length = 1147
Score = 87.8 bits (208), Expect = 4e-17
Identities = 87/317 (27%), Positives = 126/317 (39%), Gaps = 28/317 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF--FLRATHGRVHSD-AGVYWCEA 87
L+C G P+P RW+ G + D+ AG F + + V D AG Y C
Sbjct: 89 LHCFFSGYPAPKPRWFHNGREISEDSDA----AGFRFESYGKTLVFNVTQDKAGKYDCRF 144
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
R+ N + A P + +++G+ V+ +C G P P V + KNG
Sbjct: 145 ATQQDIDRTFNVVVEAAPYWPLG--PPPNTNTSEGEKVIFDCTT-YGKPTPKVTFYKNGV 201
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGR-----YQCIARNAAGTRESAIATLKIHIKP 202
+ D R +L++G L I D ++ G+ YQC + N G + + KP
Sbjct: 202 EIESQKDDR-YLIEGTRLTIFDVKKGTYGKGDNAVYQCKSENKHGWLWTNFYLNLLAFKP 260
Query: 203 YLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRR----SAGGGNMPLGRVKVLDDGS 256
L+ P E+V A G VT +C+ P V W + G +P V G
Sbjct: 261 QLLIDPGKEEVEAVAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGV---GK 317
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTC- 314
L V A+EGEY C N G + L V P + P V +G R C
Sbjct: 318 LVFSEVTAAEEGEYECIGTNKYGQATGLITLKVRKPTIVQPFPRVEEVRMAGEEMRLACD 377
Query: 315 -TATGRPEPTMFWSVEG 330
TA + E W V+G
Sbjct: 378 ATADNQLEVKYEWLVDG 394
Score = 74.5 bits (175), Expect = 4e-13
Identities = 71/297 (23%), Positives = 119/297 (40%), Gaps = 20/297 (6%)
Query: 11 APYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
APY + P + + + +C G P+P + +YK GV + S L G +
Sbjct: 161 APYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTI 220
Query: 70 ----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP--ESKQSAQGD 123
+ T+G+ D VY C++ N +G + N L++ + + ++P E ++ G
Sbjct: 221 FDVKKGTYGK--GDNAVYQCKSENKHGWLWT-NFYLNLLAFKPQLLIDPGKEEVEAVAGK 277
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
V LEC SP V W+ + G LV + + G Y+CI
Sbjct: 278 KVTLEC-KFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGT 336
Query: 184 NAAGTRESAIATLKIHIKPYLITG-PE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
N G + + + TLK+ KP ++ P + V G + C D +V + G
Sbjct: 337 NKYG-QATGLITLKVR-KPTIVQPFPRVEEVRMAGEEMRLACDATADNQLEVKYEWLVDG 394
Query: 242 GNMPLGRV-----KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
++P R+ K+ DD SL + N D +Y C + V + D P
Sbjct: 395 KSLPEDRISSGHYKIDDDHSLVISNPTQDDTAKYKCVVSTKLDQVEKEIKIQFKDVP 451
Score = 39.9 bits (89), Expect = 0.011
Identities = 58/287 (20%), Positives = 98/287 (34%), Gaps = 24/287 (8%)
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGE 269
+A G+ C G P P W + + + G + NV G+
Sbjct: 80 IALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGKTLVFNVTQDKAGK 139
Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSV 328
Y C + + + V P L P + N G F CT G+P P + +
Sbjct: 140 YDCRFATQQD-IDRTFNVVVEAAPYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYK 198
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND---SRNTIV-CSAVNYAGSSFVR 384
G + D+Y + +G T LTI D K N + C + N G +
Sbjct: 199 NG---VEIESQKDDRY----LIEG-TRLTIFDVKKGTYGKGDNAVYQCKSENKHGWLWTN 250
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
L + + +P +I G C +P + W E + +
Sbjct: 251 FYLNLLAF--KPQLLIDPGKEEVEAVAGKKVTLECKFFASPNAAVKW--EAPMISGSKGN 306
Query: 445 NVTND----GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ D G LV ++ ++ G Y C+ ++++G+ L V P
Sbjct: 307 QIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQATGLITLKVRKP 353
Score = 33.9 bits (74), Expect = 0.71
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 725 QTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
+T + VP P + + + TTV L W+ + Q NG TGY + W+D
Sbjct: 672 RTGEGVPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGNFTGYKITY-WVD 721
>U50067-2|AAY86218.1| 1328|Caenorhabditis elegans Sensory axon
guidance protein 7,isoform b protein.
Length = 1328
Score = 87.8 bits (208), Expect = 4e-17
Identities = 87/317 (27%), Positives = 126/317 (39%), Gaps = 28/317 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF--FLRATHGRVHSD-AGVYWCEA 87
L+C G P+P RW+ G + D+ AG F + + V D AG Y C
Sbjct: 273 LHCFFSGYPAPKPRWFHNGREISEDSDA----AGFRFESYGKTLVFNVTQDKAGKYDCRF 328
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
R+ N + A P + +++G+ V+ +C G P P V + KNG
Sbjct: 329 ATQQDIDRTFNVVVEAAPYWPLG--PPPNTNTSEGEKVIFDCTT-YGKPTPKVTFYKNGV 385
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGR-----YQCIARNAAGTRESAIATLKIHIKP 202
+ D R +L++G L I D ++ G+ YQC + N G + + KP
Sbjct: 386 EIESQKDDR-YLIEGTRLTIFDVKKGTYGKGDNAVYQCKSENKHGWLWTNFYLNLLAFKP 444
Query: 203 YLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRR----SAGGGNMPLGRVKVLDDGS 256
L+ P E+V A G VT +C+ P V W + G +P V G
Sbjct: 445 QLLIDPGKEEVEAVAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGV---GK 501
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTC- 314
L V A+EGEY C N G + L V P + P V +G R C
Sbjct: 502 LVFSEVTAAEEGEYECIGTNKYGQATGLITLKVRKPTIVQPFPRVEEVRMAGEEMRLACD 561
Query: 315 -TATGRPEPTMFWSVEG 330
TA + E W V+G
Sbjct: 562 ATADNQLEVKYEWLVDG 578
Score = 85.4 bits (202), Expect = 2e-16
Identities = 118/491 (24%), Positives = 177/491 (36%), Gaps = 50/491 (10%)
Query: 30 TLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPA---GGLFFLRATHGRVHSDAGVYWC 85
T++C A G+P P+ RW K G + S ++ G L F R SDAG+Y C
Sbjct: 64 TIHCYANGNPRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDE----SDAGLYQC 119
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
EA NS GTA R + +R EPE GD C PP +P VYW
Sbjct: 120 EAENSNGTAVDRPVRVQETWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILM 179
Query: 146 G-QTLLFDGDSRMHLV--DGGNLVIQDARQTD--AGR-YQCIARNAA------GTRESAI 193
G + F+ S H+ + G L +TD + R Y C A N G + S
Sbjct: 180 GKEPGHFETISSSHISSNEQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQ 239
Query: 194 ATLKIHIKPYLITGPEDVVAQT------GSSVTFQCRVGGDPLPDVLWRRSAG--GGNMP 245
T + E V Q+ G+ C G P P W + +
Sbjct: 240 ITNNKRRSLQQMPPTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSD 299
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS-PNSVNV 304
+ G + NV G+Y C + + + V P L P + N
Sbjct: 300 AAGFRFESYGKTLVFNVTQDKAGKYDCRFATQQD-IDRTFNVVVEAAPYWPLGPPPNTNT 358
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK- 363
G F CT G+P P + + G + D+Y + +G T LTI D K
Sbjct: 359 SEGEKVIFDCTTYGKPTPKVTFYKNG---VEIESQKDDRY----LIEG-TRLTIFDVKKG 410
Query: 364 --NDSRNTIV-CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
N + C + N G + L + + +P +I G C
Sbjct: 411 TYGKGDNAVYQCKSENKHGWLWTNFYLNLLA--FKPQLLIDPGKEEVEAVAGKKVTLECK 468
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTND----GTLVLKDLDKSDSGTYTCVASSRHGKY 476
+P + W E + + + D G LV ++ ++ G Y C+ ++++G+
Sbjct: 469 FFASPNAAVKW--EAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQA 526
Query: 477 VWSGALLVDSP 487
L V P
Sbjct: 527 TGLITLKVRKP 537
Score = 74.5 bits (175), Expect = 4e-13
Identities = 71/297 (23%), Positives = 119/297 (40%), Gaps = 20/297 (6%)
Query: 11 APYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
APY + P + + + +C G P+P + +YK GV + S L G +
Sbjct: 345 APYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTI 404
Query: 70 ----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP--ESKQSAQGD 123
+ T+G+ D VY C++ N +G + N L++ + + ++P E ++ G
Sbjct: 405 FDVKKGTYGK--GDNAVYQCKSENKHGWLWT-NFYLNLLAFKPQLLIDPGKEEVEAVAGK 461
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
V LEC SP V W+ + G LV + + G Y+CI
Sbjct: 462 KVTLEC-KFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGT 520
Query: 184 NAAGTRESAIATLKIHIKPYLITG-PE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
N G + + + TLK+ KP ++ P + V G + C D +V + G
Sbjct: 521 NKYG-QATGLITLKVR-KPTIVQPFPRVEEVRMAGEEMRLACDATADNQLEVKYEWLVDG 578
Query: 242 GNMPLGRV-----KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
++P R+ K+ DD SL + N D +Y C + V + D P
Sbjct: 579 KSLPEDRISSGHYKIDDDHSLVISNPTQDDTAKYKCVVSTKLDQVEKEIKIQFKDVP 635
Score = 60.5 bits (140), Expect = 7e-09
Identities = 101/452 (22%), Positives = 167/452 (36%), Gaps = 56/452 (12%)
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDTV- 125
FL G + S + W +NA T++ V E+ + ES ++ G+ +
Sbjct: 6 FLLLLTGHI-SSGSIDWSAIETPPQFVHDKNADTVYFKV--EKSGMSDESAKNTPGNLLE 62
Query: 126 -VLECLPPRGSPEPNVYWKKNGQTLL--FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
+ C G+P P+ WKK+G+T L + + G+LV ++DAG YQC A
Sbjct: 63 QTIHCYA-NGNPRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESDAGLYQCEA 121
Query: 183 RNAAGTR-ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW----R 236
N+ GT + + + I+ + PE VV + G C +P V W +
Sbjct: 122 ENSNGTAVDRPVRVQETWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILMGK 181
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILAD---EGEYSCEAEN------------SVGAV 281
+ + + G+L V D + Y+C AEN S+
Sbjct: 182 EPGHFETISSSHISSNEQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQIT 241
Query: 282 SASGYLTVYDPPSIN-LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG---NRTIIFP 337
+ PP+ ++ +S GN + C +G P P W G +
Sbjct: 242 NNKRRSLQQMPPTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSDAA 301
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
G + Y T VF+ +T + K D R +A + V +
Sbjct: 302 GFRFESYGKTLVFN----VTQDKAGKYDCR---------FATQQDIDRTFNVVVEAAPYW 348
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKD 456
P+ P N +F CT P P + +Y G E Q R + L + D
Sbjct: 349 PL--GPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTIFD 406
Query: 457 L-----DKSDSGTYTCVASSRHGKYVWSGALL 483
+ K D+ Y C + ++HG ++W+ L
Sbjct: 407 VKKGTYGKGDNAVYQCKSENKHG-WLWTNFYL 437
Score = 33.9 bits (74), Expect = 0.71
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 725 QTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
+T + VP P + + + TTV L W+ + Q NG TGY + W+D
Sbjct: 856 RTGEGVPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGNFTGYKITY-WVD 905
>U50067-1|AAZ32800.1| 1331|Caenorhabditis elegans Sensory axon
guidance protein 7,isoform c protein.
Length = 1331
Score = 87.8 bits (208), Expect = 4e-17
Identities = 87/317 (27%), Positives = 126/317 (39%), Gaps = 28/317 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF--FLRATHGRVHSD-AGVYWCEA 87
L+C G P+P RW+ G + D+ AG F + + V D AG Y C
Sbjct: 273 LHCFFSGYPAPKPRWFHNGREISEDSDA----AGFRFESYGKTLVFNVTQDKAGKYDCRF 328
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
R+ N + A P + +++G+ V+ +C G P P V + KNG
Sbjct: 329 ATQQDIDRTFNVVVEAAPYWPLG--PPPNTNTSEGEKVIFDCTT-YGKPTPKVTFYKNGV 385
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGR-----YQCIARNAAGTRESAIATLKIHIKP 202
+ D R +L++G L I D ++ G+ YQC + N G + + KP
Sbjct: 386 EIESQKDDR-YLIEGTRLTIFDVKKGTYGKGDNAVYQCKSENKHGWLWTNFYLNLLAFKP 444
Query: 203 YLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRR----SAGGGNMPLGRVKVLDDGS 256
L+ P E+V A G VT +C+ P V W + G +P V G
Sbjct: 445 QLLIDPGKEEVEAVAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGV---GK 501
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTC- 314
L V A+EGEY C N G + L V P + P V +G R C
Sbjct: 502 LVFSEVTAAEEGEYECIGTNKYGQATGLITLKVRKPTIVQPFPRVEEVRMAGEEMRLACD 561
Query: 315 -TATGRPEPTMFWSVEG 330
TA + E W V+G
Sbjct: 562 ATADNQLEVKYEWLVDG 578
Score = 85.4 bits (202), Expect = 2e-16
Identities = 118/491 (24%), Positives = 177/491 (36%), Gaps = 50/491 (10%)
Query: 30 TLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPA---GGLFFLRATHGRVHSDAGVYWC 85
T++C A G+P P+ RW K G + S ++ G L F R SDAG+Y C
Sbjct: 64 TIHCYANGNPRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDE----SDAGLYQC 119
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
EA NS GTA R + +R EPE GD C PP +P VYW
Sbjct: 120 EAENSNGTAVDRPVRVQETWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILM 179
Query: 146 G-QTLLFDGDSRMHLV--DGGNLVIQDARQTD--AGR-YQCIARNAA------GTRESAI 193
G + F+ S H+ + G L +TD + R Y C A N G + S
Sbjct: 180 GKEPGHFETISSSHISSNEQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQ 239
Query: 194 ATLKIHIKPYLITGPEDVVAQT------GSSVTFQCRVGGDPLPDVLWRRSAG--GGNMP 245
T + E V Q+ G+ C G P P W + +
Sbjct: 240 ITNNKRRSLQQMPPTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSD 299
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS-PNSVNV 304
+ G + NV G+Y C + + + V P L P + N
Sbjct: 300 AAGFRFESYGKTLVFNVTQDKAGKYDCRFATQQD-IDRTFNVVVEAAPYWPLGPPPNTNT 358
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK- 363
G F CT G+P P + + G + D+Y + +G T LTI D K
Sbjct: 359 SEGEKVIFDCTTYGKPTPKVTFYKNG---VEIESQKDDRY----LIEG-TRLTIFDVKKG 410
Query: 364 --NDSRNTIV-CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
N + C + N G + L + + +P +I G C
Sbjct: 411 TYGKGDNAVYQCKSENKHGWLWTNFYLNLLA--FKPQLLIDPGKEEVEAVAGKKVTLECK 468
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTND----GTLVLKDLDKSDSGTYTCVASSRHGKY 476
+P + W E + + + D G LV ++ ++ G Y C+ ++++G+
Sbjct: 469 FFASPNAAVKW--EAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQA 526
Query: 477 VWSGALLVDSP 487
L V P
Sbjct: 527 TGLITLKVRKP 537
Score = 74.5 bits (175), Expect = 4e-13
Identities = 71/297 (23%), Positives = 119/297 (40%), Gaps = 20/297 (6%)
Query: 11 APYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
APY + P + + + +C G P+P + +YK GV + S L G +
Sbjct: 345 APYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTI 404
Query: 70 ----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP--ESKQSAQGD 123
+ T+G+ D VY C++ N +G + N L++ + + ++P E ++ G
Sbjct: 405 FDVKKGTYGK--GDNAVYQCKSENKHGWLWT-NFYLNLLAFKPQLLIDPGKEEVEAVAGK 461
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
V LEC SP V W+ + G LV + + G Y+CI
Sbjct: 462 KVTLEC-KFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGT 520
Query: 184 NAAGTRESAIATLKIHIKPYLITG-PE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
N G + + + TLK+ KP ++ P + V G + C D +V + G
Sbjct: 521 NKYG-QATGLITLKVR-KPTIVQPFPRVEEVRMAGEEMRLACDATADNQLEVKYEWLVDG 578
Query: 242 GNMPLGRV-----KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
++P R+ K+ DD SL + N D +Y C + V + D P
Sbjct: 579 KSLPEDRISSGHYKIDDDHSLVISNPTQDDTAKYKCVVSTKLDQVEKEIKIQFKDVP 635
Score = 60.5 bits (140), Expect = 7e-09
Identities = 101/452 (22%), Positives = 167/452 (36%), Gaps = 56/452 (12%)
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDTV- 125
FL G + S + W +NA T++ V E+ + ES ++ G+ +
Sbjct: 6 FLLLLTGHI-SSGSIDWSAIETPPQFVHDKNADTVYFKV--EKSGMSDESAKNTPGNLLE 62
Query: 126 -VLECLPPRGSPEPNVYWKKNGQTLL--FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
+ C G+P P+ WKK+G+T L + + G+LV ++DAG YQC A
Sbjct: 63 QTIHCYA-NGNPRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESDAGLYQCEA 121
Query: 183 RNAAGTR-ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW----R 236
N+ GT + + + I+ + PE VV + G C +P V W +
Sbjct: 122 ENSNGTAVDRPVRVQETWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILMGK 181
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILAD---EGEYSCEAEN------------SVGAV 281
+ + + G+L V D + Y+C AEN S+
Sbjct: 182 EPGHFETISSSHISSNEQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQIT 241
Query: 282 SASGYLTVYDPPSIN-LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG---NRTIIFP 337
+ PP+ ++ +S GN + C +G P P W G +
Sbjct: 242 NNKRRSLQQMPPTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSDAA 301
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
G + Y T VF+ +T + K D R +A + V +
Sbjct: 302 GFRFESYGKTLVFN----VTQDKAGKYDCR---------FATQQDIDRTFNVVVEAAPYW 348
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKD 456
P+ P N +F CT P P + +Y G E Q R + L + D
Sbjct: 349 PL--GPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTIFD 406
Query: 457 L-----DKSDSGTYTCVASSRHGKYVWSGALL 483
+ K D+ Y C + ++HG ++W+ L
Sbjct: 407 VKKGTYGKGDNAVYQCKSENKHG-WLWTNFYL 437
Score = 33.9 bits (74), Expect = 0.71
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 725 QTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
+T + VP P + + + TTV L W+ + Q NG TGY + W+D
Sbjct: 856 RTGEGVPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGNFTGYKITY-WVD 905
>AB206670-1|BAD97389.1| 1147|Caenorhabditis elegans SAX-7 SHORTFORM
protein.
Length = 1147
Score = 87.8 bits (208), Expect = 4e-17
Identities = 87/317 (27%), Positives = 126/317 (39%), Gaps = 28/317 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF--FLRATHGRVHSD-AGVYWCEA 87
L+C G P+P RW+ G + D+ AG F + + V D AG Y C
Sbjct: 89 LHCFFSGYPAPKPRWFHNGREISEDSDA----AGFRFESYGKTLVFNVTQDKAGKYDCRF 144
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
R+ N + A P + +++G+ V+ +C G P P V + KNG
Sbjct: 145 ATQQDIDRTFNVVVEAAPYWPLG--PPPNTNTSEGEKVIFDCTT-YGKPTPKVTFYKNGV 201
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGR-----YQCIARNAAGTRESAIATLKIHIKP 202
+ D R +L++G L I D ++ G+ YQC + N G + + KP
Sbjct: 202 EIESQKDDR-YLIEGTRLTIFDVKKGTYGKGDNAVYQCKSENKHGWLWTNFYLNLLAFKP 260
Query: 203 YLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRR----SAGGGNMPLGRVKVLDDGS 256
L+ P E+V A G VT +C+ P V W + G +P V G
Sbjct: 261 QLLIDPGKEEVEAVAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGV---GK 317
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTC- 314
L V A+EGEY C N G + L V P + P V +G R C
Sbjct: 318 LVFSEVTAAEEGEYECIGTNKYGQATGLITLKVRKPTIVQPFPRVEEVRMAGEEMRLACD 377
Query: 315 -TATGRPEPTMFWSVEG 330
TA + E W V+G
Sbjct: 378 ATADNQLEVKYEWLVDG 394
Score = 74.5 bits (175), Expect = 4e-13
Identities = 71/297 (23%), Positives = 119/297 (40%), Gaps = 20/297 (6%)
Query: 11 APYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
APY + P + + + +C G P+P + +YK GV + S L G +
Sbjct: 161 APYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTI 220
Query: 70 ----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP--ESKQSAQGD 123
+ T+G+ D VY C++ N +G + N L++ + + ++P E ++ G
Sbjct: 221 FDVKKGTYGK--GDNAVYQCKSENKHGWLWT-NFYLNLLAFKPQLLIDPGKEEVEAVAGK 277
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
V LEC SP V W+ + G LV + + G Y+CI
Sbjct: 278 KVTLEC-KFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGT 336
Query: 184 NAAGTRESAIATLKIHIKPYLITG-PE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
N G + + + TLK+ KP ++ P + V G + C D +V + G
Sbjct: 337 NKYG-QATGLITLKVR-KPTIVQPFPRVEEVRMAGEEMRLACDATADNQLEVKYEWLVDG 394
Query: 242 GNMPLGRV-----KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
++P R+ K+ DD SL + N D +Y C + V + D P
Sbjct: 395 KSLPEDRISSGHYKIDDDHSLVISNPTQDDTAKYKCVVSTKLDQVEKEIKIQFKDVP 451
Score = 39.9 bits (89), Expect = 0.011
Identities = 58/287 (20%), Positives = 98/287 (34%), Gaps = 24/287 (8%)
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGE 269
+A G+ C G P P W + + + G + NV G+
Sbjct: 80 IALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSDAAGFRFESYGKTLVFNVTQDKAGK 139
Query: 270 YSCEAENSVGAVSASGYLTVYDPPSINLSPN-SVNVESGNVARFTCTATGRPEPTMFWSV 328
Y C + + + V P L P + N G F CT G+P P + +
Sbjct: 140 YDCRFATQQD-IDRTFNVVVEAAPYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYK 198
Query: 329 EGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND---SRNTIV-CSAVNYAGSSFVR 384
G + D+Y + +G T LTI D K N + C + N G +
Sbjct: 199 NG---VEIESQKDDRY----LIEG-TRLTIFDVKKGTYGKGDNAVYQCKSENKHGWLWTN 250
Query: 385 GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR 444
L + + +P +I G C +P + W E + +
Sbjct: 251 FYLNLLAF--KPQLLIDPGKEEVEAVAGKKVTLECKFFASPNAAVKW--EAPMISGSKGN 306
Query: 445 NVTND----GTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
+ D G LV ++ ++ G Y C+ ++++G+ L V P
Sbjct: 307 QIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQATGLITLKVRKP 353
Score = 33.9 bits (74), Expect = 0.71
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 725 QTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
+T + VP P + + + TTV L W+ + Q NG TGY + W+D
Sbjct: 672 RTGEGVPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGNFTGYKITY-WVD 721
>AB206669-1|BAD97388.1| 1331|Caenorhabditis elegans SAX-7 LONGFORM
protein.
Length = 1331
Score = 87.8 bits (208), Expect = 4e-17
Identities = 87/317 (27%), Positives = 126/317 (39%), Gaps = 28/317 (8%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF--FLRATHGRVHSD-AGVYWCEA 87
L+C G P+P RW+ G + D+ AG F + + V D AG Y C
Sbjct: 273 LHCFFSGYPAPKPRWFHNGREISEDSDA----AGFRFESYGKTLVFNVTQDKAGKYDCRF 328
Query: 88 TNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ 147
R+ N + A P + +++G+ V+ +C G P P V + KNG
Sbjct: 329 ATQQDIDRTFNVVVEAAPYWPLG--PPPNTNTSEGEKVIFDCTT-YGKPTPKVTFYKNGV 385
Query: 148 TLLFDGDSRMHLVDGGNLVIQDARQTDAGR-----YQCIARNAAGTRESAIATLKIHIKP 202
+ D R +L++G L I D ++ G+ YQC + N G + + KP
Sbjct: 386 EIESQKDDR-YLIEGTRLTIFDVKKGTYGKGDNAVYQCKSENKHGWLWTNFYLNLLAFKP 444
Query: 203 YLITGP--EDVVAQTGSSVTFQCRVGGDPLPDVLWRR----SAGGGNMPLGRVKVLDDGS 256
L+ P E+V A G VT +C+ P V W + G +P V G
Sbjct: 445 QLLIDPGKEEVEAVAGKKVTLECKFFASPNAAVKWEAPMISGSKGNQIPADAYGV---GK 501
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVE-SGNVARFTC- 314
L V A+EGEY C N G + L V P + P V +G R C
Sbjct: 502 LVFSEVTAAEEGEYECIGTNKYGQATGLITLKVRKPTIVQPFPRVEEVRMAGEEMRLACD 561
Query: 315 -TATGRPEPTMFWSVEG 330
TA + E W V+G
Sbjct: 562 ATADNQLEVKYEWLVDG 578
Score = 85.4 bits (202), Expect = 2e-16
Identities = 118/491 (24%), Positives = 177/491 (36%), Gaps = 50/491 (10%)
Query: 30 TLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPA---GGLFFLRATHGRVHSDAGVYWC 85
T++C A G+P P+ RW K G + S ++ G L F R SDAG+Y C
Sbjct: 64 TIHCYANGNPRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDE----SDAGLYQC 119
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKN 145
EA NS GTA R + +R EPE GD C PP +P VYW
Sbjct: 120 EAENSNGTAVDRPVRVQETWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILM 179
Query: 146 G-QTLLFDGDSRMHLV--DGGNLVIQDARQTD--AGR-YQCIARNAA------GTRESAI 193
G + F+ S H+ + G L +TD + R Y C A N G + S
Sbjct: 180 GKEPGHFETISSSHISSNEQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQ 239
Query: 194 ATLKIHIKPYLITGPEDVVAQT------GSSVTFQCRVGGDPLPDVLWRRSAG--GGNMP 245
T + E V Q+ G+ C G P P W + +
Sbjct: 240 ITNNKRRSLQQMPPTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSD 299
Query: 246 LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS-PNSVNV 304
+ G + NV G+Y C + + + V P L P + N
Sbjct: 300 AAGFRFESYGKTLVFNVTQDKAGKYDCRFATQQD-IDRTFNVVVEAAPYWPLGPPPNTNT 358
Query: 305 ESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK- 363
G F CT G+P P + + G + D+Y + +G T LTI D K
Sbjct: 359 SEGEKVIFDCTTYGKPTPKVTFYKNG---VEIESQKDDRY----LIEG-TRLTIFDVKKG 410
Query: 364 --NDSRNTIV-CSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
N + C + N G + L + + +P +I G C
Sbjct: 411 TYGKGDNAVYQCKSENKHGWLWTNFYLNLLA--FKPQLLIDPGKEEVEAVAGKKVTLECK 468
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTND----GTLVLKDLDKSDSGTYTCVASSRHGKY 476
+P + W E + + + D G LV ++ ++ G Y C+ ++++G+
Sbjct: 469 FFASPNAAVKW--EAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGTNKYGQA 526
Query: 477 VWSGALLVDSP 487
L V P
Sbjct: 527 TGLITLKVRKP 537
Score = 74.5 bits (175), Expect = 4e-13
Identities = 71/297 (23%), Positives = 119/297 (40%), Gaps = 20/297 (6%)
Query: 11 APYI-IEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
APY + P + + + +C G P+P + +YK GV + S L G +
Sbjct: 345 APYWPLGPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTI 404
Query: 70 ----RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP--ESKQSAQGD 123
+ T+G+ D VY C++ N +G + N L++ + + ++P E ++ G
Sbjct: 405 FDVKKGTYGK--GDNAVYQCKSENKHGWLWT-NFYLNLLAFKPQLLIDPGKEEVEAVAGK 461
Query: 124 TVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIAR 183
V LEC SP V W+ + G LV + + G Y+CI
Sbjct: 462 KVTLEC-KFFASPNAAVKWEAPMISGSKGNQIPADAYGVGKLVFSEVTAAEEGEYECIGT 520
Query: 184 NAAGTRESAIATLKIHIKPYLITG-PE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
N G + + + TLK+ KP ++ P + V G + C D +V + G
Sbjct: 521 NKYG-QATGLITLKVR-KPTIVQPFPRVEEVRMAGEEMRLACDATADNQLEVKYEWLVDG 578
Query: 242 GNMPLGRV-----KVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
++P R+ K+ DD SL + N D +Y C + V + D P
Sbjct: 579 KSLPEDRISSGHYKIDDDHSLVISNPTQDDTAKYKCVVSTKLDQVEKEIKIQFKDVP 635
Score = 60.5 bits (140), Expect = 7e-09
Identities = 101/452 (22%), Positives = 167/452 (36%), Gaps = 56/452 (12%)
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNA-TLHVAVLREEFRLEPESKQSAQGDTV- 125
FL G + S + W +NA T++ V E+ + ES ++ G+ +
Sbjct: 6 FLLLLTGHI-SSGSIDWSAIETPPQFVHDKNADTVYFKV--EKSGMSDESAKNTPGNLLE 62
Query: 126 -VLECLPPRGSPEPNVYWKKNGQTLL--FDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
+ C G+P P+ WKK+G+T L + + G+LV ++DAG YQC A
Sbjct: 63 QTIHCYA-NGNPRPSYRWKKDGKTFLPSMFPEKVVQKPGEGSLVFSRLDESDAGLYQCEA 121
Query: 183 RNAAGTR-ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLW----R 236
N+ GT + + + I+ + PE VV + G C +P V W +
Sbjct: 122 ENSNGTAVDRPVRVQETWIRHFKTAEPEVVVVEVGDPYQRNCSPPASNPYARVYWILMGK 181
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILAD---EGEYSCEAEN------------SVGAV 281
+ + + G+L V D + Y+C AEN S+
Sbjct: 182 EPGHFETISSSHISSNEQGTLFFHYVNETDFKSDRYYTCTAENIELKDYKFGNQFSLQIT 241
Query: 282 SASGYLTVYDPPSIN-LSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG---NRTIIFP 337
+ PP+ ++ +S GN + C +G P P W G +
Sbjct: 242 NNKRRSLQQMPPTEQYVNQSSPIALQGNQHKLHCFFSGYPAPKPRWFHNGREISEDSDAA 301
Query: 338 GMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP 397
G + Y T VF+ +T + K D R +A + V +
Sbjct: 302 GFRFESYGKTLVFN----VTQDKAGKYDCR---------FATQQDIDRTFNVVVEAAPYW 348
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKD 456
P+ P N +F CT P P + +Y G E Q R + L + D
Sbjct: 349 PL--GPPPNTNTSEGEKVIFDCTTYGKPTPKVTFYKNGVEIESQKDDRYLIEGTRLTIFD 406
Query: 457 L-----DKSDSGTYTCVASSRHGKYVWSGALL 483
+ K D+ Y C + ++HG ++W+ L
Sbjct: 407 VKKGTYGKGDNAVYQCKSENKHG-WLWTNFYL 437
Score = 33.9 bits (74), Expect = 0.71
Identities = 17/51 (33%), Positives = 26/51 (50%), Gaps = 1/51 (1%)
Query: 725 QTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLD 775
+T + VP P + + + TTV L W+ + Q NG TGY + W+D
Sbjct: 856 RTGEGVPSSIPSGLRVLEKSGTTVTLAWNGVDPQTANGNFTGYKITY-WVD 905
>Z93395-4|CAB07707.1| 2295|Caenorhabditis elegans Hypothetical protein
ZC101.2c protein.
Length = 2295
Score = 86.6 bits (205), Expect = 9e-17
Identities = 120/491 (24%), Positives = 197/491 (40%), Gaps = 57/491 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G AP I P + TV + PA C G P ++W + + + IL G F
Sbjct: 1413 GAAPQI--DPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN---GILERDG--F 1465
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE-EFRLEPESKQSAQGDTVV 126
LR ++H DAG Y C +T G+ + S A L+V + + +++P + +G+
Sbjct: 1466 LRIDKSQLH-DAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQTVNEGEPSR 1524
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+ C P G P + + K G+ L +R GNL I ++D Y CIA +
Sbjct: 1525 IRCWVP-GHPNIQLQFVKRGRRPL-PAHARF---SQGNLEIPRTLKSDEDEYICIATDPT 1579
Query: 187 GTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
R ++ +K + I P + GS +C V G P + +RR +G N
Sbjct: 1580 TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVPGHPSVQLTFRRVSGQLNE 1639
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTVY------------- 290
++G L + L DEG+Y C A + GA S TV+
Sbjct: 1640 DADE----NNGLLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEAH 1695
Query: 291 -DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
+PP+ + P + N + G +F C TG P P + W+ P S + T +
Sbjct: 1696 QEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWT--------GPNGSPLPHDVTPL 1747
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYA---GSSFVRGKLTVTSDDDRPPPIITNGPSN 406
+ + ++ N + + A G+ + LTV ++ P I+T G
Sbjct: 1748 EPNILDFSNGRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVG--- 1804
Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYF----EGEALIQNHRRNVTNDGTLVLKDLDKSDS 462
+ L +K A A PEP + W E L + + ++ + ++ ++
Sbjct: 1805 EPLQVKCEAF---GAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNA 1861
Query: 463 GTYTCVASSRH 473
G YTC SS H
Sbjct: 1862 GVYTCKGSSAH 1872
Score = 85.4 bits (202), Expect = 2e-16
Identities = 119/477 (24%), Positives = 177/477 (37%), Gaps = 48/477 (10%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAG 64
SG P + P + V +PA C G P I W++ GG L + G
Sbjct: 1222 SGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLP-----HGVYQTG 1276
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L+ ++H AG Y C A N YGT +S A L V +++P + +
Sbjct: 1277 NA--LKIPQSQLHH-AGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQP 1333
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+C P G+ + W + G L G G L I A + G+Y C A +
Sbjct: 1334 ARFKCWVP-GNSNVQLRWSRPGGAPLPSGVQEQQ----GILHIPRASDQEVGQYVCTATD 1388
Query: 185 AAGTRESAIATLKIHIK----PYLITGPE-DVVAQT---GSSVTFQCRVGGDPLPDVLWR 236
+ ++++I+ P P+ D QT F+C V G P + W
Sbjct: 1389 PSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWS 1448
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--VSASGYLTVYDPPS 294
R G PL + DG LR+D L D GEY C + G+ +S L V P +
Sbjct: 1449 RKDG---RPLPNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQA 1505
Query: 295 I--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I + P V G +R C G P + + G R + P +R
Sbjct: 1506 IQPQVDPPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPL--PAHARFSQGN------ 1557
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I T K+D + +C A + + V PII P+ QT+P
Sbjct: 1558 ---LEIPRTLKSD-EDEYICIATDPTTNRPVESNPARVIVKSPIRPII--DPAEQTVPEG 1611
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
S F P + F + N + N+G L ++ + +D G Y C A
Sbjct: 1612 S--PFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-ENNGLLAVQRAELTDEGDYICTA 1665
Score = 71.7 bits (168), Expect = 3e-12
Identities = 85/374 (22%), Positives = 142/374 (37%), Gaps = 31/374 (8%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170
+EP+ + + GD V C + E +V W K G+ L +++ + G LV++
Sbjct: 1135 MEPKRQIALPGDRVHWICQVTGYTTEKIHVEWTKVGEMSL-PPNAKAY---DGYLVLKGV 1190
Query: 171 RQTDAGRYQCIARNAAG-TRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVG 226
+AG+Y+C A + A+ T+ I P + P +V G F+C V
Sbjct: 1191 EAENAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP 1250
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
G P + W R GG +P G + +L++ L G Y C A N G +
Sbjct: 1251 GIPDCQITWHREQLGGPLPHGVYQT--GNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 287 LTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
+ P I + P V+ ARF C G + WS G +
Sbjct: 1309 VLEVKKPVIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRPGGAPL---------- 1358
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----II 400
+ V + +L I + VC+A + + ++ ++ + + D PP
Sbjct: 1359 -PSGVQEQQGILHIPRASDQEV-GQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAP 1416
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
P NQT+ + A F C P + W + + N + DG L +
Sbjct: 1417 QIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN--GILERDGFLRIDKSQLH 1474
Query: 461 DSGTYTCVASSRHG 474
D+G Y C ++ G
Sbjct: 1475 DAGEYECTSTEPDG 1488
Score = 62.9 bits (146), Expect = 1e-09
Identities = 122/478 (25%), Positives = 185/478 (38%), Gaps = 58/478 (12%)
Query: 19 LDVTVARHQPATLNCRAGGSPS---PAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHG 74
L VTV +P + C A G+P P + W D P F+R H
Sbjct: 1799 LIVTVG--EPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIR--HP 1854
Query: 75 RVH-SDAGVYWCEATNSYGTARSRNATLHV---AVLREEFRLEPESKQSAQGDTVVLECL 130
V +AGVY C+ ++++ TA ++N + V + + L S+ QG+ L C
Sbjct: 1855 NVGLGNAGVYTCKGSSAHATA-TKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICT 1913
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--------IA 182
S + W+K L D + + G L + + AG Y+C IA
Sbjct: 1914 ATGSSLVDRLEWEKVDDQLPTDVEEHN---EPGLLHFPSFKNSYAGEYRCNGYRNNEIIA 1970
Query: 183 RNAAGTRESAIA--TLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239
A SA A K+ I+P P V G ++ +C V G + W
Sbjct: 1971 SAAVHVHSSANADDEPKVEIEP-----PRVRVVSQGDNIVLKCSVQGAENGEHFKWALLR 2025
Query: 240 GGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
GG + LG L+ N D G Y C E++ G V S + V
Sbjct: 2026 GGSLVRQLGTEPTLEITKADPSN----DFGVYRCNVEDNNGLVIGSAFTAVSVGQQDKSH 2081
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V + + A FTC P + W+ E + AV +G + I
Sbjct: 2082 AQIVKFDDKSDASFTCPIYSVPGSKVDWTYENG-----------DLPSKAVPNG-NKIEI 2129
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII--TNGPSNQTLPIKSMAV 416
+ D + S T VC V++ G + V G VT+ P II S+++ I A
Sbjct: 2130 KEFD-DASAGTYVCK-VSFDG-NVVEG--FVTAQMFVPDTIIQVLLEVSSESPQIGDRAW 2184
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
F C P +I+W EG + + + VT G L+ DL + ++G Y CVA ++ G
Sbjct: 2185 FDCKVTGDPSAVISWTKEGNDDLPPNAQ-VTG-GRLLFTDLKEDNAGVYRCVAKTKAG 2240
Score = 60.5 bits (140), Expect = 7e-09
Identities = 103/435 (23%), Positives = 168/435 (38%), Gaps = 48/435 (11%)
Query: 79 DAGVYWCEATN--SYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+AG Y C AT Y T + + ++ + ++P +G+ C P G
Sbjct: 1194 NAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP-GI 1252
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
P+ + W + G + GN L I ++ AGRY C A N GT +S A
Sbjct: 1253 PDCQITWHREQ----LGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 195 TLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
L++ KP +I D + QT F+C V G+ + W R GG +P G +
Sbjct: 1309 VLEVK-KP-VIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRP-GGAPLPSGVQE- 1364
Query: 252 LDDGSLRLDNVILADEGEYSCEA---ENSVGAVSASGYLTVYDPP------SINLSPNSV 302
G L + + G+Y C A ++ S L + DP + + P +
Sbjct: 1365 -QQGILHIPRASDQEVGQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQ 1423
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V + A+F C G+P + WS + R + + RD + L I+ +
Sbjct: 1424 TVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPNGILERDGF-----------LRIDKSQ 1472
Query: 363 KNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
+D+ C++ GS+ + +L V P + P QT+ + C
Sbjct: 1473 LHDA-GEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQV---DPPVQTVNEGEPSRIRCW 1528
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS-RHGKYVWS 479
P + + G + H R + G L + KSD Y C+A+ + V S
Sbjct: 1529 VPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRTLKSDEDEYICIATDPTTNRPVES 1586
Query: 480 --GALLVDSPINPNI 492
++V SPI P I
Sbjct: 1587 NPARVIVKSPIRPII 1601
Score = 54.0 bits (124), Expect = 6e-07
Identities = 59/223 (26%), Positives = 91/223 (40%), Gaps = 25/223 (11%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDA 170
+EP + G+ C+ GSP P + W NG L D + ++ L +
Sbjct: 1703 VEPRTWNGKPGERHQFRCITT-GSPTPKITWTGPNGSPLPHD----VTPLEPNILDFSNG 1757
Query: 171 RQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRV 225
R G Y C A N G A ++I P L GP+ +V G + +C
Sbjct: 1758 RSELNGDYTCTASNPIG---EASDHGNVNIGPSLTVKTNPPGPKLIVT-VGEPLQVKCEA 1813
Query: 226 ---GGDPLPDVLWRRSAGG--GNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVG 279
GDP P+V W G G++P V + + +R NV L + G Y+C+ ++
Sbjct: 1814 FGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHA 1873
Query: 280 AVSASGYLTVYDPPSIN----LSPNSVNVESGNVARFTCTATG 318
+ + Y+ V +P I L +S + G CTATG
Sbjct: 1874 TATKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICTATG 1916
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 12/135 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLV 453
P ++ +N +P + C A+ PEP I W + + R T++ GTL
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGTLT 330
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ D D G YTC A + G+ + + +V +P P PPT P
Sbjct: 331 IHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPR---------PQPPQPPTAPPQR 381
Query: 514 NVTDTSVTLSWSQNN 528
DT ++ NN
Sbjct: 382 ASCDTRGAVTPYPNN 396
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 267 EGEYSC-EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+G C + + VG V TV DPP NL V G TC A PEP +
Sbjct: 254 DGTNDCHDGSDEVGCVQP----TVVDPPQTNLQ-----VPRGTTFSLTCKAVAVPEPYIN 304
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W + P + T+ G LTI+D D + C A+N G
Sbjct: 305 WRLNWG-----PVCEPPRCLQTSE-GGYGTLTIHDAQPVD-QGAYTCEAINVKGRVLATP 357
Query: 386 KLTV-TSDDDRPPP 398
V DD RP P
Sbjct: 358 DCIVRVVDDPRPQP 371
Score = 36.7 bits (81), Expect = 0.10
Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 8/142 (5%)
Query: 152 DGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
+GD V GN + I++ AG Y C + G T ++ + +I +
Sbjct: 2113 NGDLPSKAVPNGNKIEIKEFDDASAGTYVCKV-SFDGNVVEGFVTAQMFVPDTIIQVLLE 2171
Query: 211 VVA---QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
V + Q G F C+V GDP + W + GN L + G L ++ +
Sbjct: 2172 VSSESPQIGDRAWFDCKVTGDPSAVISWTKE---GNDDLPPNAQVTGGRLLFTDLKEDNA 2228
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A+ G + L V
Sbjct: 2229 GVYRCVAKTKAGPLQTRTVLNV 2250
Score = 35.5 bits (78), Expect = 0.23
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 208 PEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P + + G V+F+CR P V W R G PL G L ++ V L
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGG----PLPSSAHDSGGRLTINPVQL 106
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV--YDPPSIN 296
+D G Y C ++ + V A L+V Y P ++
Sbjct: 107 SDAGTYICVSDYNGNTVEARATLSVVSYGPQEVS 140
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 200 IKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
++P ++ P+ ++ G++ + C+ P P + WR + G P ++ + G +
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT 328
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSAS 284
L + + D+G Y+CEA N G V A+
Sbjct: 329 LTIHDAQPVDQGAYTCEAINVKGRVLAT 356
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 12 PYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P +++ P ++ V R +L C+A P P I W + V + R + + G +
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINW-RLNWGPVCEPPRCLQTSEGGYGTL 329
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
H D G Y CEA N G
Sbjct: 330 TIHDAQPVDQGAYTCEAINVKG 351
Score = 33.1 bits (72), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 114 PESKQSAQGDTVVLECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
P K+ G V EC S P V W + G L S H GG L I +
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL----PSSAH-DSGGRLTINPVQ 105
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI 198
+DAG Y C++ T E A ATL +
Sbjct: 106 LSDAGTYICVSDYNGNTVE-ARATLSV 131
Score = 32.3 bits (70), Expect = 2.2
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDA 175
Q +G T L C PEP + W+ N + + + +GG L I DA+ D
Sbjct: 282 QVPRGTTFSLTCKAV-AVPEPYINWRLNWGPVC-EPPRCLQTSEGGYGTLTIHDAQPVDQ 339
Query: 176 GRYQCIARNAAG 187
G Y C A N G
Sbjct: 340 GAYTCEAINVKG 351
>Z93375-7|CAB07568.1| 2295|Caenorhabditis elegans Hypothetical protein
ZC101.2c protein.
Length = 2295
Score = 86.6 bits (205), Expect = 9e-17
Identities = 120/491 (24%), Positives = 197/491 (40%), Gaps = 57/491 (11%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF 68
G AP I P + TV + PA C G P ++W + + + IL G F
Sbjct: 1413 GAAPQI--DPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN---GILERDG--F 1465
Query: 69 LRATHGRVHSDAGVYWCEATNSYGTAR-SRNATLHVAVLRE-EFRLEPESKQSAQGDTVV 126
LR ++H DAG Y C +T G+ + S A L+V + + +++P + +G+
Sbjct: 1466 LRIDKSQLH-DAGEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQVDPPVQTVNEGEPSR 1524
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAA 186
+ C P G P + + K G+ L +R GNL I ++D Y CIA +
Sbjct: 1525 IRCWVP-GHPNIQLQFVKRGRRPL-PAHARF---SQGNLEIPRTLKSDEDEYICIATDPT 1579
Query: 187 GTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNM 244
R ++ +K + I P + GS +C V G P + +RR +G N
Sbjct: 1580 TNRPVESNPARVIVKSPIRPIIDPAEQTVPEGSPFKIRCYVPGHPSVQLTFRRVSGQLNE 1639
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTVY------------- 290
++G L + L DEG+Y C A + GA S TV+
Sbjct: 1640 DADE----NNGLLAVQRAELTDEGDYICTARDPDTGAPIDSTPATVHVTNAAAPPQVEAH 1695
Query: 291 -DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV 349
+PP+ + P + N + G +F C TG P P + W+ P S + T +
Sbjct: 1696 QEPPTAVVEPRTWNGKPGERHQFRCITTGSPTPKITWT--------GPNGSPLPHDVTPL 1747
Query: 350 FDGVTVLTINDTDKNDSRNTIVCSAVNYA---GSSFVRGKLTVTSDDDRPPPIITNGPSN 406
+ + ++ N + + A G+ + LTV ++ P I+T G
Sbjct: 1748 EPNILDFSNGRSELNGDYTCTASNPIGEASDHGNVNIGPSLTVKTNPPGPKLIVTVG--- 1804
Query: 407 QTLPIKSMAVFPCTAICTPEPIIAWYF----EGEALIQNHRRNVTNDGTLVLKDLDKSDS 462
+ L +K A A PEP + W E L + + ++ + ++ ++
Sbjct: 1805 EPLQVKCEAF---GAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNA 1861
Query: 463 GTYTCVASSRH 473
G YTC SS H
Sbjct: 1862 GVYTCKGSSAH 1872
Score = 85.4 bits (202), Expect = 2e-16
Identities = 119/477 (24%), Positives = 177/477 (37%), Gaps = 48/477 (10%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYK---GGVLVVSDTHRSILPAG 64
SG P + P + V +PA C G P I W++ GG L + G
Sbjct: 1222 SGRPPQPVIDPPHLVVNEGEPAAFRCWVPGIPDCQITWHREQLGGPLP-----HGVYQTG 1276
Query: 65 GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDT 124
L+ ++H AG Y C A N YGT +S A L V +++P + +
Sbjct: 1277 NA--LKIPQSQLHH-AGRYICSAANQYGTGQSPPAVLEVKKPVIPPKVDPIRQTVDRDQP 1333
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+C P G+ + W + G L G G L I A + G+Y C A +
Sbjct: 1334 ARFKCWVP-GNSNVQLRWSRPGGAPLPSGVQEQQ----GILHIPRASDQEVGQYVCTATD 1388
Query: 185 AAGTRESAIATLKIHIK----PYLITGPE-DVVAQT---GSSVTFQCRVGGDPLPDVLWR 236
+ ++++I+ P P+ D QT F+C V G P + W
Sbjct: 1389 PSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWS 1448
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA--VSASGYLTVYDPPS 294
R G PL + DG LR+D L D GEY C + G+ +S L V P +
Sbjct: 1449 RKDG---RPLPNGILERDGFLRIDKSQLHDAGEYECTSTEPDGSTQLSPPARLNVNQPQA 1505
Query: 295 I--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
I + P V G +R C G P + + G R + P +R
Sbjct: 1506 IQPQVDPPVQTVNEGEPSRIRCWVPGHPNIQLQFVKRGRRPL--PAHARFSQGN------ 1557
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
L I T K+D + +C A + + V PII P+ QT+P
Sbjct: 1558 ---LEIPRTLKSD-EDEYICIATDPTTNRPVESNPARVIVKSPIRPII--DPAEQTVPEG 1611
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
S F P + F + N + N+G L ++ + +D G Y C A
Sbjct: 1612 S--PFKIRCYVPGHPSVQLTFRRVSGQLNEDAD-ENNGLLAVQRAELTDEGDYICTA 1665
Score = 71.7 bits (168), Expect = 3e-12
Identities = 85/374 (22%), Positives = 142/374 (37%), Gaps = 31/374 (8%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDA 170
+EP+ + + GD V C + E +V W K G+ L +++ + G LV++
Sbjct: 1135 MEPKRQIALPGDRVHWICQVTGYTTEKIHVEWTKVGEMSL-PPNAKAY---DGYLVLKGV 1190
Query: 171 RQTDAGRYQCIARNAAG-TRESAIATLKIHIK---PYLITGPEDVVAQTGSSVTFQCRVG 226
+AG+Y+C A + A+ T+ I P + P +V G F+C V
Sbjct: 1191 EAENAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP 1250
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
G P + W R GG +P G + +L++ L G Y C A N G +
Sbjct: 1251 GIPDCQITWHREQLGGPLPHGVYQT--GNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 287 LTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKY 344
+ P I + P V+ ARF C G + WS G +
Sbjct: 1309 VLEVKKPVIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRPGGAPL---------- 1358
Query: 345 HATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPP----II 400
+ V + +L I + VC+A + + ++ ++ + + D PP
Sbjct: 1359 -PSGVQEQQGILHIPRASDQEV-GQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAP 1416
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS 460
P NQT+ + A F C P + W + + N + DG L +
Sbjct: 1417 QIDPPNQTVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPN--GILERDGFLRIDKSQLH 1474
Query: 461 DSGTYTCVASSRHG 474
D+G Y C ++ G
Sbjct: 1475 DAGEYECTSTEPDG 1488
Score = 62.9 bits (146), Expect = 1e-09
Identities = 122/478 (25%), Positives = 185/478 (38%), Gaps = 58/478 (12%)
Query: 19 LDVTVARHQPATLNCRAGGSPS---PAIRWYKGGVLVVSDTHRSILPAG-GLFFLRATHG 74
L VTV +P + C A G+P P + W D P F+R H
Sbjct: 1799 LIVTVG--EPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIR--HP 1854
Query: 75 RVH-SDAGVYWCEATNSYGTARSRNATLHV---AVLREEFRLEPESKQSAQGDTVVLECL 130
V +AGVY C+ ++++ TA ++N + V + + L S+ QG+ L C
Sbjct: 1855 NVGLGNAGVYTCKGSSAHATA-TKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICT 1913
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC--------IA 182
S + W+K L D + + G L + + AG Y+C IA
Sbjct: 1914 ATGSSLVDRLEWEKVDDQLPTDVEEHN---EPGLLHFPSFKNSYAGEYRCNGYRNNEIIA 1970
Query: 183 RNAAGTRESAIA--TLKIHIKPYLITGPEDVVAQTGSSVTFQCRV-GGDPLPDVLWRRSA 239
A SA A K+ I+P P V G ++ +C V G + W
Sbjct: 1971 SAAVHVHSSANADDEPKVEIEP-----PRVRVVSQGDNIVLKCSVQGAENGEHFKWALLR 2025
Query: 240 GGGNM-PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLS 298
GG + LG L+ N D G Y C E++ G V S + V
Sbjct: 2026 GGSLVRQLGTEPTLEITKADPSN----DFGVYRCNVEDNNGLVIGSAFTAVSVGQQDKSH 2081
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
V + + A FTC P + W+ E + AV +G + I
Sbjct: 2082 AQIVKFDDKSDASFTCPIYSVPGSKVDWTYENG-----------DLPSKAVPNG-NKIEI 2129
Query: 359 NDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII--TNGPSNQTLPIKSMAV 416
+ D + S T VC V++ G + V G VT+ P II S+++ I A
Sbjct: 2130 KEFD-DASAGTYVCK-VSFDG-NVVEG--FVTAQMFVPDTIIQVLLEVSSESPQIGDRAW 2184
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
F C P +I+W EG + + + VT G L+ DL + ++G Y CVA ++ G
Sbjct: 2185 FDCKVTGDPSAVISWTKEGNDDLPPNAQ-VTG-GRLLFTDLKEDNAGVYRCVAKTKAG 2240
Score = 60.5 bits (140), Expect = 7e-09
Identities = 103/435 (23%), Positives = 168/435 (38%), Gaps = 48/435 (11%)
Query: 79 DAGVYWCEATN--SYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
+AG Y C AT Y T + + ++ + ++P +G+ C P G
Sbjct: 1194 NAGQYRCTATTITQYATDDALLTISKRISGRPPQPVIDPPHLVVNEGEPAAFRCWVP-GI 1252
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESAIA 194
P+ + W + G + GN L I ++ AGRY C A N GT +S A
Sbjct: 1253 PDCQITWHREQ----LGGPLPHGVYQTGNALKIPQSQLHHAGRYICSAANQYGTGQSPPA 1308
Query: 195 TLKIHIKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
L++ KP +I D + QT F+C V G+ + W R GG +P G +
Sbjct: 1309 VLEVK-KP-VIPPKVDPIRQTVDRDQPARFKCWVPGNSNVQLRWSRP-GGAPLPSGVQE- 1364
Query: 252 LDDGSLRLDNVILADEGEYSCEA---ENSVGAVSASGYLTVYDPP------SINLSPNSV 302
G L + + G+Y C A ++ S L + DP + + P +
Sbjct: 1365 -QQGILHIPRASDQEVGQYVCTATDPSDNTPLQSEPVQLNIRDPAPPQRGAAPQIDPPNQ 1423
Query: 303 NVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTD 362
V + A+F C G+P + WS + R + + RD + L I+ +
Sbjct: 1424 TVNVNDPAQFRCWVPGQPRAQLKWSRKDGRPLPNGILERDGF-----------LRIDKSQ 1472
Query: 363 KNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCT 420
+D+ C++ GS+ + +L V P + P QT+ + C
Sbjct: 1473 LHDA-GEYECTSTEPDGSTQLSPPARLNVNQPQAIQPQV---DPPVQTVNEGEPSRIRCW 1528
Query: 421 AICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS-RHGKYVWS 479
P + + G + H R + G L + KSD Y C+A+ + V S
Sbjct: 1529 VPGHPNIQLQFVKRGRRPLPAHAR--FSQGNLEIPRTLKSDEDEYICIATDPTTNRPVES 1586
Query: 480 --GALLVDSPINPNI 492
++V SPI P I
Sbjct: 1587 NPARVIVKSPIRPII 1601
Score = 54.0 bits (124), Expect = 6e-07
Identities = 59/223 (26%), Positives = 91/223 (40%), Gaps = 25/223 (11%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLVDGGNLVIQDA 170
+EP + G+ C+ GSP P + W NG L D + ++ L +
Sbjct: 1703 VEPRTWNGKPGERHQFRCITT-GSPTPKITWTGPNGSPLPHD----VTPLEPNILDFSNG 1757
Query: 171 RQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT-----GPEDVVAQTGSSVTFQCRV 225
R G Y C A N G A ++I P L GP+ +V G + +C
Sbjct: 1758 RSELNGDYTCTASNPIG---EASDHGNVNIGPSLTVKTNPPGPKLIVT-VGEPLQVKCEA 1813
Query: 226 ---GGDPLPDVLWRRSAGG--GNMPLGRVKV-LDDGSLRLDNVILADEGEYSCEAENSVG 279
GDP P+V W G G++P V + + +R NV L + G Y+C+ ++
Sbjct: 1814 FGAPGDPEPEVEWLHDPGPERGDLPDDFKPVTISEQFIRHPNVGLGNAGVYTCKGSSAHA 1873
Query: 280 AVSASGYLTVYDPPSIN----LSPNSVNVESGNVARFTCTATG 318
+ + Y+ V +P I L +S + G CTATG
Sbjct: 1874 TATKNIYIEVVEPSRIATVSILGGSSQWFDQGEKGELICTATG 1916
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 12/135 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLV 453
P ++ +N +P + C A+ PEP I W + + R T++ GTL
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGTLT 330
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ D D G YTC A + G+ + + +V +P P PPT P
Sbjct: 331 IHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPR---------PQPPQPPTAPPQR 381
Query: 514 NVTDTSVTLSWSQNN 528
DT ++ NN
Sbjct: 382 ASCDTRGAVTPYPNN 396
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 267 EGEYSC-EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+G C + + VG V TV DPP NL V G TC A PEP +
Sbjct: 254 DGTNDCHDGSDEVGCVQP----TVVDPPQTNLQ-----VPRGTTFSLTCKAVAVPEPYIN 304
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W + P + T+ G LTI+D D + C A+N G
Sbjct: 305 WRLNWG-----PVCEPPRCLQTSE-GGYGTLTIHDAQPVD-QGAYTCEAINVKGRVLATP 357
Query: 386 KLTV-TSDDDRPPP 398
V DD RP P
Sbjct: 358 DCIVRVVDDPRPQP 371
Score = 36.7 bits (81), Expect = 0.10
Identities = 35/142 (24%), Positives = 55/142 (38%), Gaps = 8/142 (5%)
Query: 152 DGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPED 210
+GD V GN + I++ AG Y C + G T ++ + +I +
Sbjct: 2113 NGDLPSKAVPNGNKIEIKEFDDASAGTYVCKV-SFDGNVVEGFVTAQMFVPDTIIQVLLE 2171
Query: 211 VVA---QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADE 267
V + Q G F C+V GDP + W + GN L + G L ++ +
Sbjct: 2172 VSSESPQIGDRAWFDCKVTGDPSAVISWTKE---GNDDLPPNAQVTGGRLLFTDLKEDNA 2228
Query: 268 GEYSCEAENSVGAVSASGYLTV 289
G Y C A+ G + L V
Sbjct: 2229 GVYRCVAKTKAGPLQTRTVLNV 2250
Score = 35.5 bits (78), Expect = 0.23
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 208 PEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P + + G V+F+CR P V W R G PL G L ++ V L
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGG----PLPSSAHDSGGRLTINPVQL 106
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV--YDPPSIN 296
+D G Y C ++ + V A L+V Y P ++
Sbjct: 107 SDAGTYICVSDYNGNTVEARATLSVVSYGPQEVS 140
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 200 IKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
++P ++ P+ ++ G++ + C+ P P + WR + G P ++ + G +
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT 328
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSAS 284
L + + D+G Y+CEA N G V A+
Sbjct: 329 LTIHDAQPVDQGAYTCEAINVKGRVLAT 356
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 12 PYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P +++ P ++ V R +L C+A P P I W + V + R + + G +
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINW-RLNWGPVCEPPRCLQTSEGGYGTL 329
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
H D G Y CEA N G
Sbjct: 330 TIHDAQPVDQGAYTCEAINVKG 351
Score = 33.1 bits (72), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 114 PESKQSAQGDTVVLECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
P K+ G V EC S P V W + G L S H GG L I +
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL----PSSAH-DSGGRLTINPVQ 105
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI 198
+DAG Y C++ T E A ATL +
Sbjct: 106 LSDAGTYICVSDYNGNTVE-ARATLSV 131
Score = 32.3 bits (70), Expect = 2.2
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDA 175
Q +G T L C PEP + W+ N + + + +GG L I DA+ D
Sbjct: 282 QVPRGTTFSLTCKAV-AVPEPYINWRLNWGPVC-EPPRCLQTSEGGYGTLTIHDAQPVDQ 339
Query: 176 GRYQCIARNAAG 187
G Y C A N G
Sbjct: 340 GAYTCEAINVKG 351
>AY753200-1|AAV31408.1| 402|Caenorhabditis elegans UNC-89 protein.
Length = 402
Score = 85.0 bits (201), Expect = 3e-16
Identities = 80/277 (28%), Positives = 120/277 (43%), Gaps = 18/277 (6%)
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSLRLD--NVILAD 266
D ++V F+ RV G+P P V W G RV++ + DGS+++ N+ + D
Sbjct: 18 DKTETVDNTVVFEVRVEGEPKPTVTWYLK-GEELKQSDRVEIREFDGSIKISIKNIKIED 76
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPP---SINLSPNSVNVESGNVARFTCTATGRPEPT 323
GE A NS G+ LTV P +L P S+ VE G+ A F+ A G P PT
Sbjct: 77 AGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPT 136
Query: 324 MFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV--NYAGSS 381
WSV G + +R + V DG ++LTI+ N + S V N G+
Sbjct: 137 YEWSVNGRKVRDGQEGARVTRDESTV-DGASILTIDTATYYSEVNHLTISVVAENTLGAE 195
Query: 382 FVRGKLTVTSDDDRPP-PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ 440
+LT+ + +PP P +T QT+ +A F E W+ +G+ +
Sbjct: 196 ETGAQLTI--EPKKPPAPKLTRDLKLQTVNKTDLAHFEVVVEHATE--CKWFLDGKEITT 251
Query: 441 NHRRNVTNDGTLVLK---DLDKSDSGTYTCVASSRHG 474
V+ D + D SGT + VAS+ G
Sbjct: 252 AQGVTVSKDDQFEFRCSIDTTMFGSGTVSVVASNAAG 288
Score = 60.9 bits (141), Expect = 5e-09
Identities = 96/395 (24%), Positives = 152/395 (38%), Gaps = 40/395 (10%)
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDA 175
K +TVV E + G P+P V W G+ L + DG + I++ + DA
Sbjct: 19 KTETVDNTVVFE-VRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISIKNIKIEDA 77
Query: 176 GRYQCIARNAAGTRESAIATLKIHIKPY---LITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
G + +A N+ G+ E+ A L + KP+ P + + GS F G PLP
Sbjct: 78 GEIRAVATNSEGSDETK-AKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSAHAFGIPLPT 136
Query: 233 VLWRRSA-----GGGNMPLGRVKVLDDGS--LRLDNVILADEGEY---SCEAENSVGAVS 282
W + G + R + DG+ L +D E + S AEN++GA
Sbjct: 137 YEWSVNGRKVRDGQEGARVTRDESTVDGASILTIDTATYYSEVNHLTISVVAENTLGAEE 196
Query: 283 ASGYLTV--YDPPSINLSPN--SVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338
LT+ PP+ L+ + V ++A F E W ++G G
Sbjct: 197 TGAQLTIEPKKPPAPKLTRDLKLQTVNKTDLAHFEVVVEHATE--CKWFLDGKEITTAQG 254
Query: 339 MSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPP 397
++ K D DT S T+ A N AGS + +L V + +
Sbjct: 255 VTVSK------DDQFEFRCSIDTTMFGS-GTVSVVASNAAGSVETKTELKVLETPKETKK 307
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT-----NDGTL 452
P T+ + + + I P+ WY G L+++ + VT N +L
Sbjct: 308 PEFTD--KLRDMEVTKGDTVQMDVIALHSPLYKWYQNGN-LLEDGKNGVTIKNEENKSSL 364
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
++ + DSG T AS+ G S L V+ P
Sbjct: 365 IIP--NAQDSGKITVEASNEVGSSESSAQLTVNPP 397
Score = 42.7 bits (96), Expect = 0.002
Identities = 35/137 (25%), Positives = 49/137 (35%), Gaps = 3/137 (2%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P +E +D T R G P P + WY G + I G +
Sbjct: 10 PKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDGSIKISI 69
Query: 72 THGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLECL 130
+ ++ DAG ATNS G+ ++ T+ EF L P S +G V
Sbjct: 70 KNIKI-EDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFDLRPVSLTVEKGSEAVFSA- 127
Query: 131 PPRGSPEPNVYWKKNGQ 147
G P P W NG+
Sbjct: 128 HAFGIPLPTYEWSVNGR 144
Score = 39.9 bits (89), Expect = 0.011
Identities = 33/142 (23%), Positives = 55/142 (38%), Gaps = 5/142 (3%)
Query: 392 DDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN-DG 450
+ + PP ++T + + VF P+P + WY +GE L Q+ R + DG
Sbjct: 4 EKQKKPPKFVEILVDKTETVDNTVVFEVRVEGEPKPTVTWYLKGEELKQSDRVEIREFDG 63
Query: 451 T--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD-SPINPNIHFFRAADVSSLPGPP 507
+ + +K++ D+G VA++ G L V P P R ++ G
Sbjct: 64 SIKISIKNIKIEDAGEIRAVATNSEGSDETKAKLTVQKKPFAPEFD-LRPVSLTVEKGSE 122
Query: 508 TKPITHNVTDTSVTLSWSQNNK 529
H T WS N +
Sbjct: 123 AVFSAHAFGIPLPTYEWSVNGR 144
Score = 31.9 bits (69), Expect = 2.9
Identities = 37/131 (28%), Positives = 54/131 (41%), Gaps = 7/131 (5%)
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
D +G +A NAAG+ E+ LK+ P PE VT V D
Sbjct: 270 DTTMFGSGTVSVVASNAAGSVETK-TELKVLETPKETKKPEFTDKLRDMEVTKGDTVQMD 328
Query: 229 --PLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA---DEGEYSCEAENSVGAVSA 283
L L++ G + G+ V ++I+ D G+ + EA N VG+ +
Sbjct: 329 VIALHSPLYKWYQNGNLLEDGKNGVTIKNEENKSSLIIPNAQDSGKITVEASNEVGSSES 388
Query: 284 SGYLTVYDPPS 294
S LTV +PPS
Sbjct: 389 SAQLTV-NPPS 398
>Z68006-8|CAA91999.1| 1328|Caenorhabditis elegans Hypothetical
protein K09C8.5 protein.
Length = 1328
Score = 83.8 bits (198), Expect = 7e-16
Identities = 57/177 (32%), Positives = 87/177 (49%), Gaps = 12/177 (6%)
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAG 176
S G+T+ L+C G P P + W Q L +SR H + +G L I TD G
Sbjct: 363 SRDGETLELKC-EASGEPTPTITWLFEKQKLT---ESRKHKLTKNGSVLKIFPFLNTDIG 418
Query: 177 RYQCIARNAAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
+Y+C+A N ++ + +LK +P +I P D A G VT +C G P+PDV+W
Sbjct: 419 QYECVASNGEESKSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVW 478
Query: 236 RRSAGGGNMPLGRVK-VLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
G +P + + D ++ L + V D G ++C+A NSVG+ A+ L V
Sbjct: 479 LFE--GIRIPRRNTRYTISDNNIELTIEKVTRHDSGVFTCQAVNSVGSAVATANLLV 533
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 12/186 (6%)
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEG 268
D ++ G ++ +C G+P P + W + K+ +GS L++ + D G
Sbjct: 360 DTTSRDGETLELKCEASGEPTPTITWLFEKQKLTESR-KHKLTKNGSVLKIFPFLNTDIG 418
Query: 269 EYSCEAENSVGAVSA--SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
+Y C A N + S S L + P I +P N G C A G P P + W
Sbjct: 419 QYECVASNGEESKSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVW 478
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
EG R P +Y + D LTI ++DS C AVN GS+
Sbjct: 479 LFEGIR---IP-RRNTRY---TISDNNIELTIEKVTRHDS-GVFTCQAVNSVGSAVATAN 530
Query: 387 LTVTSD 392
L V ++
Sbjct: 531 LLVGAE 536
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 14/188 (7%)
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G C A+G P PT+ W E + SR K+ T + + +TD
Sbjct: 366 GETLELKCEASGEPTPTITWLFEKQKLT----ESR-KHKLTKNGSVLKIFPFLNTDIGQY 420
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N S + + S + P+I + P + I C A P
Sbjct: 421 E----CVASNGEES---KSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPV 473
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
P + W FEG + + + R +D L ++ + + DSG +TC A + G V + LLV
Sbjct: 474 PDVVWLFEGIRIPRRNTRYTISDNNIELTIEKVTRHDSGVFTCQAVNSVGSAVATANLLV 533
Query: 485 DSPINPNI 492
+ + +
Sbjct: 534 GAELTEKV 541
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P II+ P+D Q TL C A G P P + W G+ + R + +
Sbjct: 443 EQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVWLFEGIRIPRRNTRYTISDNN---I 499
Query: 70 RATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREE 109
T +V D+GV+ C+A NS G+A + L A L E+
Sbjct: 500 ELTIEKVTRHDSGVFTCQAVNSVGSAVATANLLVGAELTEK 540
Score = 48.0 bits (109), Expect = 4e-05
Identities = 49/185 (26%), Positives = 80/185 (43%), Gaps = 17/185 (9%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
LD T + L C A G P+P I W ++ L S H+ + G + + ++
Sbjct: 359 LDTTSRDGETLELKCEASGEPTPTITWLFEKQKLTESRKHK-LTKNGSVLKI---FPFLN 414
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVLECLPPRG 134
+D G Y C A+N S++ V++ E + P + G V L C +G
Sbjct: 415 TDIGQYECVASNG---EESKSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRC-NAKG 470
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAI 193
P P+V W G + ++R + D L I+ + D+G + C A N+ G SA+
Sbjct: 471 FPVPDVVWLFEG-IRIPRRNTRYTISDNNIELTIEKVTRHDSGVFTCQAVNSVG---SAV 526
Query: 194 ATLKI 198
AT +
Sbjct: 527 ATANL 531
>Z68005-6|CAA91994.1| 1328|Caenorhabditis elegans Hypothetical
protein K09C8.5 protein.
Length = 1328
Score = 83.8 bits (198), Expect = 7e-16
Identities = 57/177 (32%), Positives = 87/177 (49%), Gaps = 12/177 (6%)
Query: 119 SAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLV--DGGNLVIQDARQTDAG 176
S G+T+ L+C G P P + W Q L +SR H + +G L I TD G
Sbjct: 363 SRDGETLELKC-EASGEPTPTITWLFEKQKLT---ESRKHKLTKNGSVLKIFPFLNTDIG 418
Query: 177 RYQCIARNAAGTRESAIA-TLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
+Y+C+A N ++ + +LK +P +I P D A G VT +C G P+PDV+W
Sbjct: 419 QYECVASNGEESKSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVW 478
Query: 236 RRSAGGGNMPLGRVK-VLDDGSLRL--DNVILADEGEYSCEAENSVGAVSASGYLTV 289
G +P + + D ++ L + V D G ++C+A NSVG+ A+ L V
Sbjct: 479 LFE--GIRIPRRNTRYTISDNNIELTIEKVTRHDSGVFTCQAVNSVGSAVATANLLV 533
Score = 57.6 bits (133), Expect = 5e-08
Identities = 50/186 (26%), Positives = 75/186 (40%), Gaps = 12/186 (6%)
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEG 268
D ++ G ++ +C G+P P + W + K+ +GS L++ + D G
Sbjct: 360 DTTSRDGETLELKCEASGEPTPTITWLFEKQKLTESR-KHKLTKNGSVLKIFPFLNTDIG 418
Query: 269 EYSCEAENSVGAVSA--SGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
+Y C A N + S S L + P I +P N G C A G P P + W
Sbjct: 419 QYECVASNGEESKSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVW 478
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
EG R P +Y + D LTI ++DS C AVN GS+
Sbjct: 479 LFEGIR---IP-RRNTRY---TISDNNIELTIEKVTRHDS-GVFTCQAVNSVGSAVATAN 530
Query: 387 LTVTSD 392
L V ++
Sbjct: 531 LLVGAE 536
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/188 (24%), Positives = 74/188 (39%), Gaps = 14/188 (7%)
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G C A+G P PT+ W E + SR K+ T + + +TD
Sbjct: 366 GETLELKCEASGEPTPTITWLFEKQKLT----ESR-KHKLTKNGSVLKIFPFLNTDIGQY 420
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPE 426
C A N S + + S + P+I + P + I C A P
Sbjct: 421 E----CVASNGEES---KSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRCNAKGFPV 473
Query: 427 PIIAWYFEGEALIQNHRRNVTNDGT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
P + W FEG + + + R +D L ++ + + DSG +TC A + G V + LLV
Sbjct: 474 PDVVWLFEGIRIPRRNTRYTISDNNIELTIEKVTRHDSGVFTCQAVNSVGSAVATANLLV 533
Query: 485 DSPINPNI 492
+ + +
Sbjct: 534 GAELTEKV 541
Score = 48.4 bits (110), Expect = 3e-05
Identities = 32/101 (31%), Positives = 46/101 (45%), Gaps = 4/101 (3%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
E P II+ P+D Q TL C A G P P + W G+ + R + +
Sbjct: 443 EQPVIIDAPMDTNATIGQQVTLRCNAKGFPVPDVVWLFEGIRIPRRNTRYTISDNN---I 499
Query: 70 RATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREE 109
T +V D+GV+ C+A NS G+A + L A L E+
Sbjct: 500 ELTIEKVTRHDSGVFTCQAVNSVGSAVATANLLVGAELTEK 540
Score = 48.0 bits (109), Expect = 4e-05
Identities = 49/185 (26%), Positives = 80/185 (43%), Gaps = 17/185 (9%)
Query: 19 LDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRATHGRVH 77
LD T + L C A G P+P I W ++ L S H+ + G + + ++
Sbjct: 359 LDTTSRDGETLELKCEASGEPTPTITWLFEKQKLTESRKHK-LTKNGSVLKI---FPFLN 414
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRL---EPESKQSAQGDTVVLECLPPRG 134
+D G Y C A+N S++ V++ E + P + G V L C +G
Sbjct: 415 TDIGQYECVASNG---EESKSHIFSVSLKESEQPVIIDAPMDTNATIGQQVTLRC-NAKG 470
Query: 135 SPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRYQCIARNAAGTRESAI 193
P P+V W G + ++R + D L I+ + D+G + C A N+ G SA+
Sbjct: 471 FPVPDVVWLFEG-IRIPRRNTRYTISDNNIELTIEKVTRHDSGVFTCQAVNSVG---SAV 526
Query: 194 ATLKI 198
AT +
Sbjct: 527 ATANL 531
>AY819766-1|AAV69856.1| 4250|Caenorhabditis elegans kettin protein.
Length = 4250
Score = 77.4 bits (182), Expect = 6e-14
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 45/325 (13%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
T G+AP + D+ + ++ PA +C+ GG P P I+W+K G + +D ++ GG
Sbjct: 3927 TQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGA 3986
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-----EEFRLEPESKQSAQ 121
+ L+ ++ + +DAG+Y A N G AR + A L+V + + EE + ++Q
Sbjct: 3987 YKLKFSN-IISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGKGAEEGPRYEAPRFTSQ 4044
Query: 122 GDTVVLE-------CLPPRGSPEPNVYWKKNGQTLLF-DGDSRMHLVDGGNLVIQDARQT 173
+V++ G P+P + W +N + + DG L I AR
Sbjct: 4045 IQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSKGEAILRISAARNE 4104
Query: 174 D-----------AGRYQCIARNAAGTRESAIATLKIHI---------------KPYLITG 207
D AG+ +A R IA I P+ I
Sbjct: 4105 DVAEYKVEASNPAGKASSVANLVLTPRSGRIAKSTISRGGSASYQSSDKAAADSPHFIAK 4164
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVIL 264
D+ A+ G +V F V G+P P V W + G VK+ DG L L V
Sbjct: 4165 LSDISARQGHTVKFSAEVDGNPEPTVQW-QFKGKPISASNNVKISRDGKRAILELARVTP 4223
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV 289
GEY N GA ++ LT+
Sbjct: 4224 DSAGEYQIVIRNDKGAATSQAKLTL 4248
Score = 62.1 bits (144), Expect = 2e-09
Identities = 57/218 (26%), Positives = 90/218 (41%), Gaps = 28/218 (12%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
G+ V W K+G+ + + + +L I + AG Y NAAGT ES
Sbjct: 3858 GAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVES- 3916
Query: 193 IATLKIHIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+A L + P+ D+ Q F C++GG+P P + W + G +P
Sbjct: 3917 LANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKD--GQPLPN 3974
Query: 247 -GRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV------------- 289
R +V+++G L+ N+I D G Y A+N VG L V
Sbjct: 3975 DDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 4034
Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
Y+ P + V+ G A+F+ +G P+PT+ W
Sbjct: 4035 RYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRW 4072
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 15/199 (7%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDG-GNL 165
+F + P+S + +TV G+P P++ W+K+ T++ G + DG G L
Sbjct: 68 QFLVHPQSVAAKAFETVTFSAKVV-GTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 126
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK----PYLITGPEDVVAQTGSSVTF 221
+I+ DA Y +ARN G+ +S + + K P + G SV
Sbjct: 127 IIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVKL 186
Query: 222 QCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
C+ G+ + W + + GG+ + ++ +L ++N + + G Y C+A N
Sbjct: 187 YCKAAGEGV-SFKWFKDNEPISSGGSYAVDNKG--NETTLHINNATMKEGGWYRCDATNK 243
Query: 278 VGAVSASGYLTVYDPPSIN 296
G + G + V N
Sbjct: 244 HGTTTLKGRVVVNSRQKFN 262
Score = 53.2 bits (122), Expect = 1e-06
Identities = 73/294 (24%), Positives = 114/294 (38%), Gaps = 34/294 (11%)
Query: 35 AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH-GRV-HSDAGVYWCEATNSYG 92
AG +P + W K G + S T R+++ + H GR+ +S AG Y N+ G
Sbjct: 3857 AGAAPVK-VTWLKDGKEIKS-TFRTLITTTPTN--SSLHIGRLENSHAGEYTVRLENAAG 3912
Query: 93 TARS-RNATLHVAVLR---EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T S N T+ + +F + Q C G P+P + W K+GQ
Sbjct: 3913 TVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSC-QIGGEPKPTIQWFKDGQP 3971
Query: 149 LLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---- 201
L D R +V+ G L + TDAG Y+ +A+N G A L ++++
Sbjct: 3972 L--PNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGK 4028
Query: 202 ----------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + + +V G F + G P P + W R+ G
Sbjct: 4029 GAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEIS 4088
Query: 252 LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
G LR+ D EY EA N G S+ L V P S ++ ++++
Sbjct: 4089 QSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANL-VLTPRSGRIAKSTIS 4141
Score = 52.8 bits (121), Expect = 1e-06
Identities = 53/193 (27%), Positives = 79/193 (40%), Gaps = 16/193 (8%)
Query: 118 QSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDA 175
Q + D C L P G P V W+ NG + + S + L+I+ DA
Sbjct: 3092 QLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADA 3151
Query: 176 GRYQCIARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQ--TGSSVTFQCRVG--G 227
G Y+C+A N G+ S A+ + P ++ D V G S+ +CRV
Sbjct: 3152 GEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPIN 3211
Query: 228 DPLPDVLWRRSAGGGNMP-LGRVK-VLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSA 283
DP V W R+ G +P R K + G + LD + D G+Y N G +
Sbjct: 3212 DPRLHVEWLRN--GAPLPEASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3269
Query: 284 SGYLTVYDPPSIN 296
+TV PS++
Sbjct: 3270 KTKITVLPRPSLD 3282
Score = 52.0 bits (119), Expect = 2e-06
Identities = 51/199 (25%), Positives = 78/199 (39%), Gaps = 11/199 (5%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP + P SV ++ F+ G P P++ W + + T+I G KY D
Sbjct: 66 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQ-KSDGTVIQSG---GKYKIENGPD 121
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
G L I D +D+ + + A N GS R L V P T + TL
Sbjct: 122 GSGRLIIEKVDAHDA-DMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYD 180
Query: 412 KSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTC 467
C A E + W+ + E + V N G TL + + + G Y C
Sbjct: 181 GDSVKLYCKA--AGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYRC 238
Query: 468 VASSRHGKYVWSGALLVDS 486
A+++HG G ++V+S
Sbjct: 239 DATNKHGTTTLKGRVVVNS 257
Score = 50.8 bits (116), Expect = 6e-06
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 17/199 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLRL 259
P + P+ V A+ +VTF +V G P P + W++S G G+ K+ + DGS RL
Sbjct: 67 PQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 126
Query: 260 --DNVILADEGEYSCEAENSVGAVSASGYLTVY-----DPPSINLSPNSVNVESGNVARF 312
+ V D Y A N G+ + L V + P S + G+ +
Sbjct: 127 IIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVKL 186
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C A G E F + N I G +A T L IN+ + C
Sbjct: 187 YCKAAG--EGVSFKWFKDNEPISSGGS-----YAVDNKGNETTLHINNATMKEG-GWYRC 238
Query: 373 SAVNYAGSSFVRGKLTVTS 391
A N G++ ++G++ V S
Sbjct: 239 DATNKHGTTTLKGRVVVNS 257
Score = 46.0 bits (104), Expect = 2e-04
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP------NSVNVESG 307
+ SL + + + GEY+ EN+ G V + LTV P + +P N + ++
Sbjct: 3887 NSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQN 3946
Query: 308 NVARFTCTATGRPEPTMFWSVEG 330
A F+C G P+PT+ W +G
Sbjct: 3947 GPAEFSCQIGGEPKPTIQWFKDG 3969
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/162 (26%), Positives = 67/162 (41%), Gaps = 8/162 (4%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P+ ++W G + S G+ L H + +DAG Y C ATN G+A S
Sbjct: 3109 GDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKH-LIAADAGEYKCVATNVKGSATS 3167
Query: 97 -----RNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLL 150
++ + + +L + +GD++ LEC + P P +V W +NG L
Sbjct: 3168 VGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLP 3227
Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRES 191
+ G +L I A D G Y+ + RN G S
Sbjct: 3228 EASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3269
Score = 44.0 bits (99), Expect = 7e-04
Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 13/191 (6%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+ + P + P V + T + + G+P+P++ W K V+ + + G
Sbjct: 61 LVNARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGP 120
Query: 66 LFFLRATHGRVHS-DAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQ 121
R +V + DA +Y A N G+ +SR N + EF + +S
Sbjct: 121 DGSGRLIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYD 180
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GN---LVIQDARQTDAGR 177
GD+V L C + W K+ + + G + VD GN L I +A + G
Sbjct: 181 GDSVKLYC--KAAGEGVSFKWFKDNEPISSGGS---YAVDNKGNETTLHINNATMKEGGW 235
Query: 178 YQCIARNAAGT 188
Y+C A N GT
Sbjct: 236 YRCDATNKHGT 246
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 8/102 (7%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P + ++ V ARF C TG P P + W + GN+ + + FDG
Sbjct: 3459 PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCL-------HGHRFKLNFDG 3511
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
+ LT++ + +D+ +V A N G + L + +DD
Sbjct: 3512 LHYLTVSKSRISDA-GEVVAIARNTEGETISTATLDIFQNDD 3552
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 4/102 (3%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP ++ V +QPA C G P P + W+ G + HR L GL +L
Sbjct: 3457 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHG-HRFKLNFDGLHYL 3515
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
+ R+ SDAG A N+ G S ATL + ++FR
Sbjct: 3516 TVSKSRI-SDAGEVVAIARNTEGETIS-TATLDI-FQNDDFR 3554
Score = 41.5 bits (93), Expect = 0.004
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 392 DDDRPPPIITNGPSNQT-LPIKSMAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTN 448
D D PP T+ + L A C T + P +I W+ G+ + +R +
Sbjct: 2939 DADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIH 2998
Query: 449 D-GTLVLK--DLDKSDSGTYTCVASSRHG 474
D G +VL+ + DSGT+TC A+++HG
Sbjct: 2999 DFGFVVLQLTPAEPQDSGTWTCRATNQHG 3027
Score = 41.1 bits (92), Expect = 0.005
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGT 188
P P + W NG+ + SR+ +++ VI D QT D+G ++C+A+NAAG
Sbjct: 2569 PVDDPTLTINWFLNGEPM--SASSRVKMINDFGWVIMDIAQTEPRDSGEWKCVAKNAAGE 2626
Query: 189 RESAIATLKIHIKPYLI 205
S AT+++ K ++
Sbjct: 2627 AVST-ATIEVQGKEVIL 2642
Score = 37.9 bits (84), Expect = 0.043
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 9/74 (12%)
Query: 422 ICTPEPI------IAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSR 472
+C EPI + W G + ++R + TN+ TL++K L +D+G Y CVA++
Sbjct: 3102 VCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNV 3161
Query: 473 HGKYVWSGALLVDS 486
G G + V+S
Sbjct: 3162 KGSATSVGKIAVES 3175
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 391 SDDDRP--PPIITNGPSNQTLPIKS--MAVFPCTA--ICTPEPIIAWYFEGEALIQNHR- 443
SDDD PP+ T + T P+K C I P I W+ +G L+ R
Sbjct: 1345 SDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGSRI 1404
Query: 444 RNVTNDGTLVLKDLD--KSDSGTYTCVASSRHGK 475
R + + G + L+ L D+GTYTC A++ G+
Sbjct: 1405 RTIHDFGYVGLEFLHIHPEDTGTYTCKATNLIGE 1438
Score = 35.9 bits (79), Expect = 0.18
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F + + Q + EC G P P V W NG L +++ L +
Sbjct: 3460 QFTIPLRNLQVTENQPARFECAVT-GYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVS 3518
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI 198
+R +DAG IARN G S ATL I
Sbjct: 3519 KSRISDAGEVVAIARNTEGETIST-ATLDI 3547
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGA 481
P+ + WY G L + RR + ND LV DL + D+G Y+ V + G+ SG
Sbjct: 1913 PKTSVQWYLNGNPLSASSRRILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQ 1972
Query: 482 L 482
L
Sbjct: 1973 L 1973
Score = 35.5 bits (78), Expect = 0.23
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGEALIQNHRRNVTNDGTLV 453
PP I S +L A F T +P + W+ GE + + R + ND V
Sbjct: 2542 PPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMINDFGWV 2601
Query: 454 LKDL---DKSDSGTYTCVASSRHGKYVWSGALLV 484
+ D+ + DSG + CVA + G+ V + + V
Sbjct: 2602 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEV 2635
Score = 35.1 bits (77), Expect = 0.31
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 110 FRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI 167
F + S++ +G + LE L P P+ V W +G L + R L G +L I
Sbjct: 428 FHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDI 487
Query: 168 QDARQTDAGRYQCIARNAAGTRES 191
D+G Y C A N G E+
Sbjct: 488 PQTSSNDSGLYSCRAFNKLGESEN 511
Score = 35.1 bits (77), Expect = 0.31
Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT--LVLKDLDKSDSGTYTCVASSR 472
A F C P P + W+ G + HR + DG L + SD+G +A +
Sbjct: 3476 ARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDAGEVVAIARNT 3535
Query: 473 HGKYVWSGAL 482
G+ + + L
Sbjct: 3536 EGETISTATL 3545
Score = 34.7 bits (76), Expect = 0.40
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 13/109 (11%)
Query: 227 GDPLPDVLWRRSAGGGNMPLG-RVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVS 282
GDP V W + G +P R+ ++ +L + ++I AD GEY C A N G+ +
Sbjct: 3109 GDPTLRVQWEHN--GHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSAT 3166
Query: 283 ASGYLTV-----YDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTM 324
+ G + V D P + L + N+ G+ C T +P +
Sbjct: 3167 SVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRL 3215
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASS 471
A F C P+P I W+ +G+ L + R V +G L ++ +D+G Y VA +
Sbjct: 3949 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 4008
Query: 472 RHGK 475
G+
Sbjct: 4009 GVGE 4012
Score = 32.7 bits (71), Expect = 1.6
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 121 QGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177
+G+ + LEC + P + W ++GQ+L G D G +L I DAG
Sbjct: 971 EGEPIHLECQVNPINDNSLKIIWLRDGQSLPH-GHRFRTFYDFGFVSLDILGFYAQDAGT 1029
Query: 178 YQCIARNAAGTRESAIATLK 197
Y C A N+ G E+ +AT++
Sbjct: 1030 YTCRAENSLGQAET-VATIR 1048
Score = 32.7 bits (71), Expect = 1.6
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGAL 482
+ W+ + + ++ HR T D DL + D+G Y CVA++RHG+ + S L
Sbjct: 3356 VEWFKDKKPVLLGHRFRSTLDFGFACLDLLYALPDDTGEYHCVATNRHGQTMISAKL 3412
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIR--WYKGGVLVVSDTHRSILPAGGL 66
+AP IE PLD + Q A + P +R W+K G +++ + G
Sbjct: 1750 DAPQFIE-PLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFGY 1808
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA 94
L H V D+GVY +A+N+ G A
Sbjct: 1809 ISLDIAH-TVPEDSGVYSVKASNAKGDA 1835
Score = 31.5 bits (68), Expect = 3.8
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 39 PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
P+ + W K G + + I G+ L + H DAGVY C NS+G A+S
Sbjct: 581 PTLRVSWLKDGQPLPNANRIQIFQNFGVVSL-SLHPTYPEDAGVYTCVLFNSHGQAQS 637
Score = 31.5 bits (68), Expect = 3.8
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 214 QTGSSVTFQCRVG--GDPLPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLD--NVILADE 267
+ G + +C+V D ++W R G ++P G R + D G + LD D
Sbjct: 970 EEGEPIHLECQVNPINDNSLKIIWLRD--GQSLPHGHRFRTFYDFGFVSLDILGFYAQDA 1027
Query: 268 GEYSCEAENSVG 279
G Y+C AENS+G
Sbjct: 1028 GTYTCRAENSLG 1039
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKYVWSGALLVD 485
W F G L + R V ND V D+D DSG YT V + G+ S VD
Sbjct: 1258 WLFNGNPLKASSRYRVLNDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1315
Score = 31.5 bits (68), Expect = 3.8
Identities = 11/40 (27%), Positives = 19/40 (47%)
Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
D P + ++ G+ +F+ G PEPT+ W +G
Sbjct: 4157 DSPHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKG 4196
Score = 31.1 bits (67), Expect = 5.0
Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 117 KQSAQ-GDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDAR 171
K+ AQ G ++ LEC L P P V W +NGQ L SR D NL I
Sbjct: 1496 KEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPL--PEASRFMPARNFDYVNLDILALY 1553
Query: 172 QTDAGRYQCIARNAAG 187
D+G Y C A +A G
Sbjct: 1554 GEDSGVYTCKAVSAFG 1569
Score = 30.3 bits (65), Expect = 8.7
Identities = 31/136 (22%), Positives = 52/136 (38%), Gaps = 2/136 (1%)
Query: 54 SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE 113
S T ++LP L + THG ++ + + + + + EFR +
Sbjct: 3269 SKTKITVLPRPSLDYTSQTHGNQQDSLESHFKQHSQAKLQLTANDIYNESDKRAPEFRTQ 3328
Query: 114 PESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDAR 171
++ +G+ E + P P V W K+ + +L R L G L + A
Sbjct: 3329 LQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACLDLLYAL 3388
Query: 172 QTDAGRYQCIARNAAG 187
D G Y C+A N G
Sbjct: 3389 PDDTGEYHCVATNRHG 3404
>AF106579-4|AAK82895.1| 4203|Caenorhabditis elegans Kettin (drosophila
actin-binding)homolog protein 1, isoform b protein.
Length = 4203
Score = 77.4 bits (182), Expect = 6e-14
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 45/325 (13%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
T G+AP + D+ + ++ PA +C+ GG P P I+W+K G + +D ++ GG
Sbjct: 3880 TQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGA 3939
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-----EEFRLEPESKQSAQ 121
+ L+ ++ + +DAG+Y A N G AR + A L+V + + EE + ++Q
Sbjct: 3940 YKLKFSN-IISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGKGAEEGPRYEAPRFTSQ 3997
Query: 122 GDTVVLE-------CLPPRGSPEPNVYWKKNGQTLLF-DGDSRMHLVDGGNLVIQDARQT 173
+V++ G P+P + W +N + + DG L I AR
Sbjct: 3998 IQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSKGEAILRISAARNE 4057
Query: 174 D-----------AGRYQCIARNAAGTRESAIATLKIHI---------------KPYLITG 207
D AG+ +A R IA I P+ I
Sbjct: 4058 DVAEYKVEASNPAGKASSVANLVLTPRSGRIAKSTISRGGSASYQSSDKAAADSPHFIAK 4117
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVIL 264
D+ A+ G +V F V G+P P V W + G VK+ DG L L V
Sbjct: 4118 LSDISARQGHTVKFSAEVDGNPEPTVQW-QFKGKPISASNNVKISRDGKRAILELARVTP 4176
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV 289
GEY N GA ++ LT+
Sbjct: 4177 DSAGEYQIVIRNDKGAATSQAKLTL 4201
Score = 62.1 bits (144), Expect = 2e-09
Identities = 57/218 (26%), Positives = 90/218 (41%), Gaps = 28/218 (12%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
G+ V W K+G+ + + + +L I + AG Y NAAGT ES
Sbjct: 3811 GAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVES- 3869
Query: 193 IATLKIHIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+A L + P+ D+ Q F C++GG+P P + W + G +P
Sbjct: 3870 LANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKD--GQPLPN 3927
Query: 247 -GRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV------------- 289
R +V+++G L+ N+I D G Y A+N VG L V
Sbjct: 3928 DDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 3987
Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
Y+ P + V+ G A+F+ +G P+PT+ W
Sbjct: 3988 RYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRW 4025
Score = 53.2 bits (122), Expect = 1e-06
Identities = 73/294 (24%), Positives = 114/294 (38%), Gaps = 34/294 (11%)
Query: 35 AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH-GRV-HSDAGVYWCEATNSYG 92
AG +P + W K G + S T R+++ + H GR+ +S AG Y N+ G
Sbjct: 3810 AGAAPVK-VTWLKDGKEIKS-TFRTLITTTPTN--SSLHIGRLENSHAGEYTVRLENAAG 3865
Query: 93 TARS-RNATLHVAVLR---EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T S N T+ + +F + Q C G P+P + W K+GQ
Sbjct: 3866 TVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSC-QIGGEPKPTIQWFKDGQP 3924
Query: 149 LLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---- 201
L D R +V+ G L + TDAG Y+ +A+N G A L ++++
Sbjct: 3925 L--PNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGK 3981
Query: 202 ----------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + + +V G F + G P P + W R+ G
Sbjct: 3982 GAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEIS 4041
Query: 252 LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
G LR+ D EY EA N G S+ L V P S ++ ++++
Sbjct: 4042 QSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANL-VLTPRSGRIAKSTIS 4094
Score = 52.8 bits (121), Expect = 1e-06
Identities = 53/193 (27%), Positives = 79/193 (40%), Gaps = 16/193 (8%)
Query: 118 QSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDA 175
Q + D C L P G P V W+ NG + + S + L+I+ DA
Sbjct: 3009 QLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADA 3068
Query: 176 GRYQCIARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQ--TGSSVTFQCRVG--G 227
G Y+C+A N G+ S A+ + P ++ D V G S+ +CRV
Sbjct: 3069 GEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPIN 3128
Query: 228 DPLPDVLWRRSAGGGNMP-LGRVK-VLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSA 283
DP V W R+ G +P R K + G + LD + D G+Y N G +
Sbjct: 3129 DPRLHVEWLRN--GAPLPEASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3186
Query: 284 SGYLTVYDPPSIN 296
+TV PS++
Sbjct: 3187 KTKITVLPRPSLD 3199
Score = 46.8 bits (106), Expect = 9e-05
Identities = 70/281 (24%), Positives = 116/281 (41%), Gaps = 34/281 (12%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLRL 259
P + P+ V A+ +VTF +V G P P + W++S G G+ K+ + DGS RL
Sbjct: 68 PQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 127
Query: 260 --DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ V D Y A N G+ +S L N+ ++ G R C AT
Sbjct: 128 IIEKVDAHDADMYMLVARNDGGSFQSS---VDNKGNETTLHINNATMKEGGWYR--CDAT 182
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
+ T +++G R ++ SR K++ A + ++T+ DK + T V +
Sbjct: 183 NKHGTT---TLKG-RVVV---NSRQKFNGPAHRE---MITLRKVDKVERSRTPVNQLQDV 232
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
+ S K + + + G S + L IK T + P IAW G+
Sbjct: 233 SAS-----KSSPKFEGSLQSQQLVEGQSAR-LEIK------YTPVEDPNLRIAWLLNGKG 280
Query: 438 LIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSRHGK 475
++ + R D L + ++ D G YT VA + G+
Sbjct: 281 ILASSRIVTFTDFGIAALEINPVNVFDQGEYTVVAVNPLGE 321
Score = 46.0 bits (104), Expect = 2e-04
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP------NSVNVESG 307
+ SL + + + GEY+ EN+ G V + LTV P + +P N + ++
Sbjct: 3840 NSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQN 3899
Query: 308 NVARFTCTATGRPEPTMFWSVEG 330
A F+C G P+PT+ W +G
Sbjct: 3900 GPAEFSCQIGGEPKPTIQWFKDG 3922
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/162 (26%), Positives = 67/162 (41%), Gaps = 8/162 (4%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P+ ++W G + S G+ L H + +DAG Y C ATN G+A S
Sbjct: 3026 GDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKH-LIAADAGEYKCVATNVKGSATS 3084
Query: 97 -----RNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLL 150
++ + + +L + +GD++ LEC + P P +V W +NG L
Sbjct: 3085 VGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLP 3144
Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRES 191
+ G +L I A D G Y+ + RN G S
Sbjct: 3145 EASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3186
Score = 42.7 bits (96), Expect = 0.002
Identities = 57/216 (26%), Positives = 86/216 (39%), Gaps = 18/216 (8%)
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT--GRPEPTMFW 326
++ A S GA + +G T D P+ + S V G T P+ + W
Sbjct: 345 QFGGTAYQSKGAQAPAG--THLDLPNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVW 402
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
++GN P S DKY T + G L I T NDS C A N G S +
Sbjct: 403 LLDGNE---LP--SNDKYRQT-LSHGFASLDIPQTSSNDS-GLYSCRAFNKLGESENQAT 455
Query: 387 LTVT--SDDDRPPPIITN-GPSNQTLPI-KSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
+ + S D P ++ P + + +S I P ++W +G+ L +
Sbjct: 456 IIIFAHSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPLPNAN 515
Query: 443 RRNV-TNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475
R + N G +L L D+G YTCV + HG+
Sbjct: 516 RIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQ 551
Score = 42.7 bits (96), Expect = 0.002
Identities = 53/194 (27%), Positives = 79/194 (40%), Gaps = 18/194 (9%)
Query: 110 FRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI 167
F + S++ +G + LE L P P+ V W +G L + R L G +L I
Sbjct: 369 FHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDI 428
Query: 168 QDARQTDAGRYQCIARNAAGTRES-AIATLKIH----IKPYLITG--PEDVVAQTGSSVT 220
D+G Y C A N G E+ A + H + P ++ P + G S
Sbjct: 429 PQTSSNDSGLYSCRAFNKLGESENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELGRSF- 487
Query: 221 FQCRVG--GDPLPDVLWRRSAGGGNMP-LGRVKVLDDG---SLRLDNVILADEGEYSCEA 274
F+ R+ DP V W + G +P R+++ + SL L D G Y+C
Sbjct: 488 FEARIQPINDPTLRVSWLKD--GQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVL 545
Query: 275 ENSVGAVSASGYLT 288
NS G +S LT
Sbjct: 546 FNSHGQAQSSAELT 559
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 8/102 (7%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P + ++ V ARF C TG P P + W + GN+ + + FDG
Sbjct: 3376 PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCL-------HGHRFKLNFDG 3428
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
+ LT++ + +D+ +V A N G + L + +DD
Sbjct: 3429 LHYLTVSKSRISDA-GEVVAIARNTEGETISTATLDIFQNDD 3469
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 4/102 (3%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP ++ V +QPA C G P P + W+ G + HR L GL +L
Sbjct: 3374 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHG-HRFKLNFDGLHYL 3432
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
+ R+ SDAG A N+ G S ATL + ++FR
Sbjct: 3433 TVSKSRI-SDAGEVVAIARNTEGETIS-TATLDI-FQNDDFR 3471
Score = 41.5 bits (93), Expect = 0.004
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 392 DDDRPPPIITNGPSNQT-LPIKSMAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTN 448
D D PP T+ + L A C T + P +I W+ G+ + +R +
Sbjct: 2856 DADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIH 2915
Query: 449 D-GTLVLK--DLDKSDSGTYTCVASSRHG 474
D G +VL+ + DSGT+TC A+++HG
Sbjct: 2916 DFGFVVLQLTPAEPQDSGTWTCRATNQHG 2944
Score = 41.1 bits (92), Expect = 0.005
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGT 188
P P + W NG+ + SR+ +++ VI D QT D+G ++C+A+NAAG
Sbjct: 2486 PVDDPTLTINWFLNGEPM--SASSRVKMINDFGWVIMDIAQTEPRDSGEWKCVAKNAAGE 2543
Query: 189 RESAIATLKIHIKPYLI 205
S AT+++ K ++
Sbjct: 2544 AVST-ATIEVQGKEVIL 2559
Score = 39.9 bits (89), Expect = 0.011
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDG-GNL 165
+F + P+S + +TV G+P P++ W+K+ T++ G + DG G L
Sbjct: 69 QFLVHPQSVAAKAFETVTFSAKVV-GTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 127
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAI 193
+I+ DA Y +ARN G+ +S++
Sbjct: 128 IIEKVDAHDADMYMLVARNDGGSFQSSV 155
Score = 37.9 bits (84), Expect = 0.043
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 9/74 (12%)
Query: 422 ICTPEPI------IAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSR 472
+C EPI + W G + ++R + TN+ TL++K L +D+G Y CVA++
Sbjct: 3019 VCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNV 3078
Query: 473 HGKYVWSGALLVDS 486
G G + V+S
Sbjct: 3079 KGSATSVGKIAVES 3092
Score = 35.9 bits (79), Expect = 0.18
Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEF------RLEPESKQSAQGDTVVLECLP 131
+D+G+Y C A N G + ++ + A ++ +++P + G + +
Sbjct: 434 NDSGLYSCRAFNKLGESENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQ 493
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGT 188
P P V W K+GQ L +R+ + +V T DAG Y C+ N+ G
Sbjct: 494 PINDPTLRVSWLKDGQPL--PNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQ 551
Query: 189 RESA 192
+S+
Sbjct: 552 AQSS 555
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 391 SDDDRP--PPIITNGPSNQTLPIKS--MAVFPCTA--ICTPEPIIAWYFEGEALIQNHR- 443
SDDD PP+ T + T P+K C I P I W+ +G L+ R
Sbjct: 1262 SDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGSRI 1321
Query: 444 RNVTNDGTLVLKDLD--KSDSGTYTCVASSRHGK 475
R + + G + L+ L D+GTYTC A++ G+
Sbjct: 1322 RTIHDFGYVGLEFLHIHPEDTGTYTCKATNLIGE 1355
Score = 35.9 bits (79), Expect = 0.18
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F + + Q + EC G P P V W NG L +++ L +
Sbjct: 3377 QFTIPLRNLQVTENQPARFECAVT-GYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVS 3435
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI 198
+R +DAG IARN G S ATL I
Sbjct: 3436 KSRISDAGEVVAIARNTEGETIST-ATLDI 3464
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGA 481
P+ + WY G L + RR + ND LV DL + D+G Y+ V + G+ SG
Sbjct: 1830 PKTSVQWYLNGNPLSASSRRILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQ 1889
Query: 482 L 482
L
Sbjct: 1890 L 1890
Score = 35.5 bits (78), Expect = 0.23
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGEALIQNHRRNVTNDGTLV 453
PP I S +L A F T +P + W+ GE + + R + ND V
Sbjct: 2459 PPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMINDFGWV 2518
Query: 454 LKDL---DKSDSGTYTCVASSRHGKYVWSGALLV 484
+ D+ + DSG + CVA + G+ V + + V
Sbjct: 2519 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEV 2552
Score = 35.1 bits (77), Expect = 0.31
Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT--LVLKDLDKSDSGTYTCVASSR 472
A F C P P + W+ G + HR + DG L + SD+G +A +
Sbjct: 3393 ARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDAGEVVAIARNT 3452
Query: 473 HGKYVWSGAL 482
G+ + + L
Sbjct: 3453 EGETISTATL 3462
Score = 34.7 bits (76), Expect = 0.40
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 13/109 (11%)
Query: 227 GDPLPDVLWRRSAGGGNMPLG-RVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVS 282
GDP V W + G +P R+ ++ +L + ++I AD GEY C A N G+ +
Sbjct: 3026 GDPTLRVQWEHN--GHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSAT 3083
Query: 283 ASGYLTV-----YDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTM 324
+ G + V D P + L + N+ G+ C T +P +
Sbjct: 3084 SVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRL 3132
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASS 471
A F C P+P I W+ +G+ L + R V +G L ++ +D+G Y VA +
Sbjct: 3902 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 3961
Query: 472 RHGK 475
G+
Sbjct: 3962 GVGE 3965
Score = 32.7 bits (71), Expect = 1.6
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 121 QGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177
+G+ + LEC + P + W ++GQ+L G D G +L I DAG
Sbjct: 888 EGEPIHLECQVNPINDNSLKIIWLRDGQSLPH-GHRFRTFYDFGFVSLDILGFYAQDAGT 946
Query: 178 YQCIARNAAGTRESAIATLK 197
Y C A N+ G E+ +AT++
Sbjct: 947 YTCRAENSLGQAET-VATIR 965
Score = 32.7 bits (71), Expect = 1.6
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGAL 482
+ W+ + + ++ HR T D DL + D+G Y CVA++RHG+ + S L
Sbjct: 3273 VEWFKDKKPVLLGHRFRSTLDFGFACLDLLYALPDDTGEYHCVATNRHGQTMISAKL 3329
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIR--WYKGGVLVVSDTHRSILPAGGL 66
+AP IE PLD + Q A + P +R W+K G +++ + G
Sbjct: 1667 DAPQFIE-PLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFGY 1725
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA 94
L H V D+GVY +A+N+ G A
Sbjct: 1726 ISLDIAH-TVPEDSGVYSVKASNAKGDA 1752
Score = 31.9 bits (69), Expect = 2.9
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP + P SV ++ F+ G P P++ W + + T+I S KY D
Sbjct: 67 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQ-KSDGTVI---QSGGKYKIENGPD 122
Query: 352 GVTVLTINDTDKNDS 366
G L I D +D+
Sbjct: 123 GSGRLIIEKVDAHDA 137
Score = 31.5 bits (68), Expect = 3.8
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 39 PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
P+ + W K G + + I G+ L + H DAGVY C NS+G A+S
Sbjct: 498 PTLRVSWLKDGQPLPNANRIQIFQNFGVVSL-SLHPTYPEDAGVYTCVLFNSHGQAQS 554
Score = 31.5 bits (68), Expect = 3.8
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 214 QTGSSVTFQCRVG--GDPLPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLD--NVILADE 267
+ G + +C+V D ++W R G ++P G R + D G + LD D
Sbjct: 887 EEGEPIHLECQVNPINDNSLKIIWLRD--GQSLPHGHRFRTFYDFGFVSLDILGFYAQDA 944
Query: 268 GEYSCEAENSVG 279
G Y+C AENS+G
Sbjct: 945 GTYTCRAENSLG 956
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKYVWSGALLVD 485
W F G L + R V ND V D+D DSG YT V + G+ S VD
Sbjct: 1175 WLFNGNPLKASSRYRVLNDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1232
Score = 31.5 bits (68), Expect = 3.8
Identities = 11/40 (27%), Positives = 19/40 (47%)
Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
D P + ++ G+ +F+ G PEPT+ W +G
Sbjct: 4110 DSPHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKG 4149
Score = 31.1 bits (67), Expect = 5.0
Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 117 KQSAQ-GDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDAR 171
K+ AQ G ++ LEC L P P V W +NGQ L SR D NL I
Sbjct: 1413 KEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPL--PEASRFMPARNFDYVNLDILALY 1470
Query: 172 QTDAGRYQCIARNAAG 187
D+G Y C A +A G
Sbjct: 1471 GEDSGVYTCKAVSAFG 1486
Score = 30.7 bits (66), Expect = 6.6
Identities = 20/87 (22%), Positives = 36/87 (41%), Gaps = 6/87 (6%)
Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-HRRNVTN----D 449
RPP + + P + F + TP P + W +IQ+ + + N
Sbjct: 66 RPPQFLVH-PQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGS 124
Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKY 476
G L+++ +D D+ Y VA + G +
Sbjct: 125 GRLIIEKVDAHDADMYMLVARNDGGSF 151
Score = 30.3 bits (65), Expect = 8.7
Identities = 20/92 (21%), Positives = 38/92 (41%), Gaps = 1/92 (1%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+ + P + P V + T + + G+P+P++ W K V+ + + G
Sbjct: 62 LVNARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGP 121
Query: 66 LFFLRATHGRVHS-DAGVYWCEATNSYGTARS 96
R +V + DA +Y A N G+ +S
Sbjct: 122 DGSGRLIIEKVDAHDADMYMLVARNDGGSFQS 153
Score = 30.3 bits (65), Expect = 8.7
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
N N+ TL + + + G Y C A+++HG G ++V+S
Sbjct: 157 NKGNETTLHINNATMKEGGWYRCDATNKHGTTTLKGRVVVNS 198
Score = 30.3 bits (65), Expect = 8.7
Identities = 31/136 (22%), Positives = 52/136 (38%), Gaps = 2/136 (1%)
Query: 54 SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE 113
S T ++LP L + THG ++ + + + + + EFR +
Sbjct: 3186 SKTKITVLPRPSLDYTSQTHGNQQDSLESHFKQHSQAKLQLTANDIYNESDKRAPEFRTQ 3245
Query: 114 PESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDAR 171
++ +G+ E + P P V W K+ + +L R L G L + A
Sbjct: 3246 LQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACLDLLYAL 3305
Query: 172 QTDAGRYQCIARNAAG 187
D G Y C+A N G
Sbjct: 3306 PDDTGEYHCVATNRHG 3321
>AF106579-2|AAM45363.1| 4447|Caenorhabditis elegans Kettin (drosophila
actin-binding)homolog protein 1, isoform c protein.
Length = 4447
Score = 77.4 bits (182), Expect = 6e-14
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 45/325 (13%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
T G+AP + D+ + ++ PA +C+ GG P P I+W+K G + +D ++ GG
Sbjct: 4124 TQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGA 4183
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-----EEFRLEPESKQSAQ 121
+ L+ ++ + +DAG+Y A N G AR + A L+V + + EE + ++Q
Sbjct: 4184 YKLKFSN-IISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGKGAEEGPRYEAPRFTSQ 4241
Query: 122 GDTVVLE-------CLPPRGSPEPNVYWKKNGQTLLF-DGDSRMHLVDGGNLVIQDARQT 173
+V++ G P+P + W +N + + DG L I AR
Sbjct: 4242 IQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSKGEAILRISAARNE 4301
Query: 174 D-----------AGRYQCIARNAAGTRESAIATLKIHI---------------KPYLITG 207
D AG+ +A R IA I P+ I
Sbjct: 4302 DVAEYKVEASNPAGKASSVANLVLTPRSGRIAKSTISRGGSASYQSSDKAAADSPHFIAK 4361
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVIL 264
D+ A+ G +V F V G+P P V W + G VK+ DG L L V
Sbjct: 4362 LSDISARQGHTVKFSAEVDGNPEPTVQW-QFKGKPISASNNVKISRDGKRAILELARVTP 4420
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV 289
GEY N GA ++ LT+
Sbjct: 4421 DSAGEYQIVIRNDKGAATSQAKLTL 4445
Score = 62.1 bits (144), Expect = 2e-09
Identities = 57/218 (26%), Positives = 90/218 (41%), Gaps = 28/218 (12%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
G+ V W K+G+ + + + +L I + AG Y NAAGT ES
Sbjct: 4055 GAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVES- 4113
Query: 193 IATLKIHIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+A L + P+ D+ Q F C++GG+P P + W + G +P
Sbjct: 4114 LANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKD--GQPLPN 4171
Query: 247 -GRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV------------- 289
R +V+++G L+ N+I D G Y A+N VG L V
Sbjct: 4172 DDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 4231
Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
Y+ P + V+ G A+F+ +G P+PT+ W
Sbjct: 4232 RYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRW 4269
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 15/199 (7%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDG-GNL 165
+F + P+S + +TV G+P P++ W+K+ T++ G + DG G L
Sbjct: 306 QFLVHPQSVAAKAFETVTFSAKVV-GTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 364
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK----PYLITGPEDVVAQTGSSVTF 221
+I+ DA Y +ARN G+ +S + + K P + G SV
Sbjct: 365 IIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVKL 424
Query: 222 QCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
C+ G+ + W + + GG+ + ++ +L ++N + + G Y C+A N
Sbjct: 425 YCKAAGEGV-SFKWFKDNEPISSGGSYAVDNKG--NETTLHINNATMKEGGWYRCDATNK 481
Query: 278 VGAVSASGYLTVYDPPSIN 296
G + G + V N
Sbjct: 482 HGTTTLKGRVVVNSRQKFN 500
Score = 53.2 bits (122), Expect = 1e-06
Identities = 73/294 (24%), Positives = 114/294 (38%), Gaps = 34/294 (11%)
Query: 35 AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH-GRV-HSDAGVYWCEATNSYG 92
AG +P + W K G + S T R+++ + H GR+ +S AG Y N+ G
Sbjct: 4054 AGAAPVK-VTWLKDGKEIKS-TFRTLITTTPTN--SSLHIGRLENSHAGEYTVRLENAAG 4109
Query: 93 TARS-RNATLHVAVLR---EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T S N T+ + +F + Q C G P+P + W K+GQ
Sbjct: 4110 TVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSC-QIGGEPKPTIQWFKDGQP 4168
Query: 149 LLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---- 201
L D R +V+ G L + TDAG Y+ +A+N G A L ++++
Sbjct: 4169 L--PNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGK 4225
Query: 202 ----------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + + +V G F + G P P + W R+ G
Sbjct: 4226 GAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEIS 4285
Query: 252 LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
G LR+ D EY EA N G S+ L V P S ++ ++++
Sbjct: 4286 QSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANL-VLTPRSGRIAKSTIS 4338
Score = 52.8 bits (121), Expect = 1e-06
Identities = 53/193 (27%), Positives = 79/193 (40%), Gaps = 16/193 (8%)
Query: 118 QSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDA 175
Q + D C L P G P V W+ NG + + S + L+I+ DA
Sbjct: 3330 QLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADA 3389
Query: 176 GRYQCIARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQ--TGSSVTFQCRVG--G 227
G Y+C+A N G+ S A+ + P ++ D V G S+ +CRV
Sbjct: 3390 GEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPIN 3449
Query: 228 DPLPDVLWRRSAGGGNMP-LGRVK-VLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSA 283
DP V W R+ G +P R K + G + LD + D G+Y N G +
Sbjct: 3450 DPRLHVEWLRN--GAPLPEASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3507
Query: 284 SGYLTVYDPPSIN 296
+TV PS++
Sbjct: 3508 KTKITVLPRPSLD 3520
Score = 52.0 bits (119), Expect = 2e-06
Identities = 51/199 (25%), Positives = 78/199 (39%), Gaps = 11/199 (5%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP + P SV ++ F+ G P P++ W + + T+I G KY D
Sbjct: 304 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQ-KSDGTVIQSG---GKYKIENGPD 359
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
G L I D +D+ + + A N GS R L V P T + TL
Sbjct: 360 GSGRLIIEKVDAHDA-DMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYD 418
Query: 412 KSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTC 467
C A E + W+ + E + V N G TL + + + G Y C
Sbjct: 419 GDSVKLYCKA--AGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYRC 476
Query: 468 VASSRHGKYVWSGALLVDS 486
A+++HG G ++V+S
Sbjct: 477 DATNKHGTTTLKGRVVVNS 495
Score = 50.8 bits (116), Expect = 6e-06
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 17/199 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLRL 259
P + P+ V A+ +VTF +V G P P + W++S G G+ K+ + DGS RL
Sbjct: 305 PQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 364
Query: 260 --DNVILADEGEYSCEAENSVGAVSASGYLTVY-----DPPSINLSPNSVNVESGNVARF 312
+ V D Y A N G+ + L V + P S + G+ +
Sbjct: 365 IIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVKL 424
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C A G E F + N I G +A T L IN+ + C
Sbjct: 425 YCKAAG--EGVSFKWFKDNEPISSGGS-----YAVDNKGNETTLHINNATMKEG-GWYRC 476
Query: 373 SAVNYAGSSFVRGKLTVTS 391
A N G++ ++G++ V S
Sbjct: 477 DATNKHGTTTLKGRVVVNS 495
Score = 46.0 bits (104), Expect = 2e-04
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP------NSVNVESG 307
+ SL + + + GEY+ EN+ G V + LTV P + +P N + ++
Sbjct: 4084 NSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQN 4143
Query: 308 NVARFTCTATGRPEPTMFWSVEG 330
A F+C G P+PT+ W +G
Sbjct: 4144 GPAEFSCQIGGEPKPTIQWFKDG 4166
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/162 (26%), Positives = 67/162 (41%), Gaps = 8/162 (4%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P+ ++W G + S G+ L H + +DAG Y C ATN G+A S
Sbjct: 3347 GDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKH-LIAADAGEYKCVATNVKGSATS 3405
Query: 97 -----RNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLL 150
++ + + +L + +GD++ LEC + P P +V W +NG L
Sbjct: 3406 VGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLP 3465
Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRES 191
+ G +L I A D G Y+ + RN G S
Sbjct: 3466 EASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3507
Score = 44.0 bits (99), Expect = 7e-04
Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 13/191 (6%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+ + P + P V + T + + G+P+P++ W K V+ + + G
Sbjct: 299 LVNARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGP 358
Query: 66 LFFLRATHGRVHS-DAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQ 121
R +V + DA +Y A N G+ +SR N + EF + +S
Sbjct: 359 DGSGRLIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYD 418
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GN---LVIQDARQTDAGR 177
GD+V L C + W K+ + + G + VD GN L I +A + G
Sbjct: 419 GDSVKLYC--KAAGEGVSFKWFKDNEPISSGGS---YAVDNKGNETTLHINNATMKEGGW 473
Query: 178 YQCIARNAAGT 188
Y+C A N GT
Sbjct: 474 YRCDATNKHGT 484
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 8/102 (7%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P + ++ V ARF C TG P P + W + GN+ + + FDG
Sbjct: 3697 PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCL-------HGHRFKLNFDG 3749
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
+ LT++ + +D+ +V A N G + L + +DD
Sbjct: 3750 LHYLTVSKSRISDA-GEVVAIARNTEGETISTATLDIFQNDD 3790
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 4/102 (3%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP ++ V +QPA C G P P + W+ G + HR L GL +L
Sbjct: 3695 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHG-HRFKLNFDGLHYL 3753
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
+ R+ SDAG A N+ G S ATL + ++FR
Sbjct: 3754 TVSKSRI-SDAGEVVAIARNTEGETIS-TATLDI-FQNDDFR 3792
Score = 41.5 bits (93), Expect = 0.004
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 392 DDDRPPPIITNGPSNQT-LPIKSMAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTN 448
D D PP T+ + L A C T + P +I W+ G+ + +R +
Sbjct: 3177 DADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIH 3236
Query: 449 D-GTLVLK--DLDKSDSGTYTCVASSRHG 474
D G +VL+ + DSGT+TC A+++HG
Sbjct: 3237 DFGFVVLQLTPAEPQDSGTWTCRATNQHG 3265
Score = 41.1 bits (92), Expect = 0.005
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGT 188
P P + W NG+ + SR+ +++ VI D QT D+G ++C+A+NAAG
Sbjct: 2807 PVDDPTLTINWFLNGEPM--SASSRVKMINDFGWVIMDIAQTEPRDSGEWKCVAKNAAGE 2864
Query: 189 RESAIATLKIHIKPYLI 205
S AT+++ K ++
Sbjct: 2865 AVST-ATIEVQGKEVIL 2880
Score = 37.9 bits (84), Expect = 0.043
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 9/74 (12%)
Query: 422 ICTPEPI------IAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSR 472
+C EPI + W G + ++R + TN+ TL++K L +D+G Y CVA++
Sbjct: 3340 VCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNV 3399
Query: 473 HGKYVWSGALLVDS 486
G G + V+S
Sbjct: 3400 KGSATSVGKIAVES 3413
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 391 SDDDRP--PPIITNGPSNQTLPIKS--MAVFPCTA--ICTPEPIIAWYFEGEALIQNHR- 443
SDDD PP+ T + T P+K C I P I W+ +G L+ R
Sbjct: 1583 SDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGSRI 1642
Query: 444 RNVTNDGTLVLKDLD--KSDSGTYTCVASSRHGK 475
R + + G + L+ L D+GTYTC A++ G+
Sbjct: 1643 RTIHDFGYVGLEFLHIHPEDTGTYTCKATNLIGE 1676
Score = 35.9 bits (79), Expect = 0.18
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F + + Q + EC G P P V W NG L +++ L +
Sbjct: 3698 QFTIPLRNLQVTENQPARFECAVT-GYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVS 3756
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI 198
+R +DAG IARN G S ATL I
Sbjct: 3757 KSRISDAGEVVAIARNTEGETIST-ATLDI 3785
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGA 481
P+ + WY G L + RR + ND LV DL + D+G Y+ V + G+ SG
Sbjct: 2151 PKTSVQWYLNGNPLSASSRRILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQ 2210
Query: 482 L 482
L
Sbjct: 2211 L 2211
Score = 35.5 bits (78), Expect = 0.23
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGEALIQNHRRNVTNDGTLV 453
PP I S +L A F T +P + W+ GE + + R + ND V
Sbjct: 2780 PPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMINDFGWV 2839
Query: 454 LKDL---DKSDSGTYTCVASSRHGKYVWSGALLV 484
+ D+ + DSG + CVA + G+ V + + V
Sbjct: 2840 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEV 2873
Score = 35.1 bits (77), Expect = 0.31
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 110 FRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI 167
F + S++ +G + LE L P P+ V W +G L + R L G +L I
Sbjct: 666 FHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDI 725
Query: 168 QDARQTDAGRYQCIARNAAGTRES 191
D+G Y C A N G E+
Sbjct: 726 PQTSSNDSGLYSCRAFNKLGESEN 749
Score = 35.1 bits (77), Expect = 0.31
Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT--LVLKDLDKSDSGTYTCVASSR 472
A F C P P + W+ G + HR + DG L + SD+G +A +
Sbjct: 3714 ARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDAGEVVAIARNT 3773
Query: 473 HGKYVWSGAL 482
G+ + + L
Sbjct: 3774 EGETISTATL 3783
Score = 34.7 bits (76), Expect = 0.40
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 13/109 (11%)
Query: 227 GDPLPDVLWRRSAGGGNMPLG-RVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVS 282
GDP V W + G +P R+ ++ +L + ++I AD GEY C A N G+ +
Sbjct: 3347 GDPTLRVQWEHN--GHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSAT 3404
Query: 283 ASGYLTV-----YDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTM 324
+ G + V D P + L + N+ G+ C T +P +
Sbjct: 3405 SVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRL 3453
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASS 471
A F C P+P I W+ +G+ L + R V +G L ++ +D+G Y VA +
Sbjct: 4146 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 4205
Query: 472 RHGK 475
G+
Sbjct: 4206 GVGE 4209
Score = 32.7 bits (71), Expect = 1.6
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 121 QGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177
+G+ + LEC + P + W ++GQ+L G D G +L I DAG
Sbjct: 1209 EGEPIHLECQVNPINDNSLKIIWLRDGQSLPH-GHRFRTFYDFGFVSLDILGFYAQDAGT 1267
Query: 178 YQCIARNAAGTRESAIATLK 197
Y C A N+ G E+ +AT++
Sbjct: 1268 YTCRAENSLGQAET-VATIR 1286
Score = 32.7 bits (71), Expect = 1.6
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGAL 482
+ W+ + + ++ HR T D DL + D+G Y CVA++RHG+ + S L
Sbjct: 3594 VEWFKDKKPVLLGHRFRSTLDFGFACLDLLYALPDDTGEYHCVATNRHGQTMISAKL 3650
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIR--WYKGGVLVVSDTHRSILPAGGL 66
+AP IE PLD + Q A + P +R W+K G +++ + G
Sbjct: 1988 DAPQFIE-PLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFGY 2046
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA 94
L H V D+GVY +A+N+ G A
Sbjct: 2047 ISLDIAH-TVPEDSGVYSVKASNAKGDA 2073
Score = 31.5 bits (68), Expect = 3.8
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 39 PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
P+ + W K G + + I G+ L + H DAGVY C NS+G A+S
Sbjct: 819 PTLRVSWLKDGQPLPNANRIQIFQNFGVVSL-SLHPTYPEDAGVYTCVLFNSHGQAQS 875
Score = 31.5 bits (68), Expect = 3.8
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 214 QTGSSVTFQCRVG--GDPLPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLD--NVILADE 267
+ G + +C+V D ++W R G ++P G R + D G + LD D
Sbjct: 1208 EEGEPIHLECQVNPINDNSLKIIWLRD--GQSLPHGHRFRTFYDFGFVSLDILGFYAQDA 1265
Query: 268 GEYSCEAENSVG 279
G Y+C AENS+G
Sbjct: 1266 GTYTCRAENSLG 1277
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKYVWSGALLVD 485
W F G L + R V ND V D+D DSG YT V + G+ S VD
Sbjct: 1496 WLFNGNPLKASSRYRVLNDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1553
Score = 31.5 bits (68), Expect = 3.8
Identities = 11/40 (27%), Positives = 19/40 (47%)
Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
D P + ++ G+ +F+ G PEPT+ W +G
Sbjct: 4354 DSPHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKG 4393
Score = 31.1 bits (67), Expect = 5.0
Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 117 KQSAQ-GDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDAR 171
K+ AQ G ++ LEC L P P V W +NGQ L SR D NL I
Sbjct: 1734 KEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPL--PEASRFMPARNFDYVNLDILALY 1791
Query: 172 QTDAGRYQCIARNAAG 187
D+G Y C A +A G
Sbjct: 1792 GEDSGVYTCKAVSAFG 1807
Score = 30.3 bits (65), Expect = 8.7
Identities = 31/136 (22%), Positives = 52/136 (38%), Gaps = 2/136 (1%)
Query: 54 SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE 113
S T ++LP L + THG ++ + + + + + EFR +
Sbjct: 3507 SKTKITVLPRPSLDYTSQTHGNQQDSLESHFKQHSQAKLQLTANDIYNESDKRAPEFRTQ 3566
Query: 114 PESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDAR 171
++ +G+ E + P P V W K+ + +L R L G L + A
Sbjct: 3567 LQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACLDLLYAL 3626
Query: 172 QTDAGRYQCIARNAAG 187
D G Y C+A N G
Sbjct: 3627 PDDTGEYHCVATNRHG 3642
>AF106579-1|AAC78200.4| 4889|Caenorhabditis elegans Kettin (drosophila
actin-binding)homolog protein 1, isoform a protein.
Length = 4889
Score = 77.4 bits (182), Expect = 6e-14
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 45/325 (13%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
T G+AP + D+ + ++ PA +C+ GG P P I+W+K G + +D ++ GG
Sbjct: 4566 TQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGA 4625
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-----EEFRLEPESKQSAQ 121
+ L+ ++ + +DAG+Y A N G AR + A L+V + + EE + ++Q
Sbjct: 4626 YKLKFSN-IISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGKGAEEGPRYEAPRFTSQ 4683
Query: 122 GDTVVLE-------CLPPRGSPEPNVYWKKNGQTLLF-DGDSRMHLVDGGNLVIQDARQT 173
+V++ G P+P + W +N + + DG L I AR
Sbjct: 4684 IQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSKGEAILRISAARNE 4743
Query: 174 D-----------AGRYQCIARNAAGTRESAIATLKIHI---------------KPYLITG 207
D AG+ +A R IA I P+ I
Sbjct: 4744 DVAEYKVEASNPAGKASSVANLVLTPRSGRIAKSTISRGGSASYQSSDKAAADSPHFIAK 4803
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVIL 264
D+ A+ G +V F V G+P P V W + G VK+ DG L L V
Sbjct: 4804 LSDISARQGHTVKFSAEVDGNPEPTVQW-QFKGKPISASNNVKISRDGKRAILELARVTP 4862
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV 289
GEY N GA ++ LT+
Sbjct: 4863 DSAGEYQIVIRNDKGAATSQAKLTL 4887
Score = 62.1 bits (144), Expect = 2e-09
Identities = 57/218 (26%), Positives = 90/218 (41%), Gaps = 28/218 (12%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
G+ V W K+G+ + + + +L I + AG Y NAAGT ES
Sbjct: 4497 GAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVES- 4555
Query: 193 IATLKIHIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+A L + P+ D+ Q F C++GG+P P + W + G +P
Sbjct: 4556 LANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKD--GQPLPN 4613
Query: 247 -GRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV------------- 289
R +V+++G L+ N+I D G Y A+N VG L V
Sbjct: 4614 DDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 4673
Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
Y+ P + V+ G A+F+ +G P+PT+ W
Sbjct: 4674 RYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRW 4711
Score = 54.4 bits (125), Expect = 5e-07
Identities = 56/203 (27%), Positives = 92/203 (45%), Gaps = 36/203 (17%)
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTD 174
K++ G+T++LEC G P+P + W K+G + D R+ DG LVI + D
Sbjct: 27 KRAVVGETIILEC-QLEGHPDPAIKWLKDGHNVSMCPDYRIE-EDGLKHRLVIPQVQAAD 84
Query: 175 AGRYQCIARNAAGTRES---------------AIATLKIHIKPYLITGPEDVV------- 212
+GR+ A N+AGT++S A + + P GP +
Sbjct: 85 SGRFTAQASNSAGTKQSTCILICAPAPTPVPGAKSAVASPAPPQTPVGPSAPIFLKELRH 144
Query: 213 --AQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA----- 265
+ G+ VTF+ RV P P++ W ++ G + R K+ D + ++I+
Sbjct: 145 QPLKPGAGVTFEGRVIAVPPPNIEWMKN--GKPLQNYRAKIEHDQKTGIISLIIPQMFND 202
Query: 266 DEGEYSCEAENSVG-AVSASGYL 287
D GEY+ +A N G A+S + L
Sbjct: 203 DAGEYTIKATNVHGEAISGAQLL 225
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 15/199 (7%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDG-GNL 165
+F + P+S + +TV G+P P++ W+K+ T++ G + DG G L
Sbjct: 707 QFLVHPQSVAAKAFETVTFSAKVV-GTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 765
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK----PYLITGPEDVVAQTGSSVTF 221
+I+ DA Y +ARN G+ +S + + K P + G SV
Sbjct: 766 IIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVKL 825
Query: 222 QCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
C+ G+ + W + + GG+ + ++ +L ++N + + G Y C+A N
Sbjct: 826 YCKAAGEGV-SFKWFKDNEPISSGGSYAVDNKG--NETTLHINNATMKEGGWYRCDATNK 882
Query: 278 VGAVSASGYLTVYDPPSIN 296
G + G + V N
Sbjct: 883 HGTTTLKGRVVVNSRQKFN 901
Score = 53.2 bits (122), Expect = 1e-06
Identities = 73/294 (24%), Positives = 114/294 (38%), Gaps = 34/294 (11%)
Query: 35 AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH-GRV-HSDAGVYWCEATNSYG 92
AG +P + W K G + S T R+++ + H GR+ +S AG Y N+ G
Sbjct: 4496 AGAAPVK-VTWLKDGKEIKS-TFRTLITTTPTN--SSLHIGRLENSHAGEYTVRLENAAG 4551
Query: 93 TARS-RNATLHVAVLR---EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T S N T+ + +F + Q C G P+P + W K+GQ
Sbjct: 4552 TVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSC-QIGGEPKPTIQWFKDGQP 4610
Query: 149 LLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---- 201
L D R +V+ G L + TDAG Y+ +A+N G A L ++++
Sbjct: 4611 L--PNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGK 4667
Query: 202 ----------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + + +V G F + G P P + W R+ G
Sbjct: 4668 GAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEIS 4727
Query: 252 LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
G LR+ D EY EA N G S+ L V P S ++ ++++
Sbjct: 4728 QSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANL-VLTPRSGRIAKSTIS 4780
Score = 52.8 bits (121), Expect = 1e-06
Identities = 53/193 (27%), Positives = 79/193 (40%), Gaps = 16/193 (8%)
Query: 118 QSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDA 175
Q + D C L P G P V W+ NG + + S + L+I+ DA
Sbjct: 3731 QLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADA 3790
Query: 176 GRYQCIARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQ--TGSSVTFQCRVG--G 227
G Y+C+A N G+ S A+ + P ++ D V G S+ +CRV
Sbjct: 3791 GEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPIN 3850
Query: 228 DPLPDVLWRRSAGGGNMP-LGRVK-VLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSA 283
DP V W R+ G +P R K + G + LD + D G+Y N G +
Sbjct: 3851 DPRLHVEWLRN--GAPLPEASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3908
Query: 284 SGYLTVYDPPSIN 296
+TV PS++
Sbjct: 3909 KTKITVLPRPSLD 3921
Score = 52.0 bits (119), Expect = 2e-06
Identities = 51/199 (25%), Positives = 78/199 (39%), Gaps = 11/199 (5%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP + P SV ++ F+ G P P++ W + + T+I G KY D
Sbjct: 705 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQ-KSDGTVIQSG---GKYKIENGPD 760
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
G L I D +D+ + + A N GS R L V P T + TL
Sbjct: 761 GSGRLIIEKVDAHDA-DMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYD 819
Query: 412 KSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTC 467
C A E + W+ + E + V N G TL + + + G Y C
Sbjct: 820 GDSVKLYCKA--AGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYRC 877
Query: 468 VASSRHGKYVWSGALLVDS 486
A+++HG G ++V+S
Sbjct: 878 DATNKHGTTTLKGRVVVNS 896
Score = 50.8 bits (116), Expect = 6e-06
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 17/199 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLRL 259
P + P+ V A+ +VTF +V G P P + W++S G G+ K+ + DGS RL
Sbjct: 706 PQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 765
Query: 260 --DNVILADEGEYSCEAENSVGAVSASGYLTVY-----DPPSINLSPNSVNVESGNVARF 312
+ V D Y A N G+ + L V + P S + G+ +
Sbjct: 766 IIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVKL 825
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C A G E F + N I G +A T L IN+ + C
Sbjct: 826 YCKAAG--EGVSFKWFKDNEPISSGGS-----YAVDNKGNETTLHINNATMKEG-GWYRC 877
Query: 373 SAVNYAGSSFVRGKLTVTS 391
A N G++ ++G++ V S
Sbjct: 878 DATNKHGTTTLKGRVVVNS 896
Score = 46.0 bits (104), Expect = 2e-04
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP------NSVNVESG 307
+ SL + + + GEY+ EN+ G V + LTV P + +P N + ++
Sbjct: 4526 NSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQN 4585
Query: 308 NVARFTCTATGRPEPTMFWSVEG 330
A F+C G P+PT+ W +G
Sbjct: 4586 GPAEFSCQIGGEPKPTIQWFKDG 4608
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/162 (26%), Positives = 67/162 (41%), Gaps = 8/162 (4%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P+ ++W G + S G+ L H + +DAG Y C ATN G+A S
Sbjct: 3748 GDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKH-LIAADAGEYKCVATNVKGSATS 3806
Query: 97 -----RNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLL 150
++ + + +L + +GD++ LEC + P P +V W +NG L
Sbjct: 3807 VGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLP 3866
Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRES 191
+ G +L I A D G Y+ + RN G S
Sbjct: 3867 EASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3908
Score = 44.0 bits (99), Expect = 7e-04
Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 13/191 (6%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+ + P + P V + T + + G+P+P++ W K V+ + + G
Sbjct: 700 LVNARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGP 759
Query: 66 LFFLRATHGRVHS-DAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQ 121
R +V + DA +Y A N G+ +SR N + EF + +S
Sbjct: 760 DGSGRLIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYD 819
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GN---LVIQDARQTDAGR 177
GD+V L C + W K+ + + G + VD GN L I +A + G
Sbjct: 820 GDSVKLYC--KAAGEGVSFKWFKDNEPISSGGS---YAVDNKGNETTLHINNATMKEGGW 874
Query: 178 YQCIARNAAGT 188
Y+C A N GT
Sbjct: 875 YRCDATNKHGT 885
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 8/102 (7%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P + ++ V ARF C TG P P + W + GN+ + + FDG
Sbjct: 4098 PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCL-------HGHRFKLNFDG 4150
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
+ LT++ + +D+ +V A N G + L + +DD
Sbjct: 4151 LHYLTVSKSRISDA-GEVVAIARNTEGETISTATLDIFQNDD 4191
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 4/102 (3%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP ++ V +QPA C G P P + W+ G + HR L GL +L
Sbjct: 4096 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHG-HRFKLNFDGLHYL 4154
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
+ R+ SDAG A N+ G S ATL + ++FR
Sbjct: 4155 TVSKSRI-SDAGEVVAIARNTEGETIS-TATLDI-FQNDDFR 4193
Score = 41.5 bits (93), Expect = 0.004
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 392 DDDRPPPIITNGPSNQT-LPIKSMAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTN 448
D D PP T+ + L A C T + P +I W+ G+ + +R +
Sbjct: 3578 DADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIH 3637
Query: 449 D-GTLVLK--DLDKSDSGTYTCVASSRHG 474
D G +VL+ + DSGT+TC A+++HG
Sbjct: 3638 DFGFVVLQLTPAEPQDSGTWTCRATNQHG 3666
Score = 41.1 bits (92), Expect = 0.005
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGT 188
P P + W NG+ + SR+ +++ VI D QT D+G ++C+A+NAAG
Sbjct: 3208 PVDDPTLTINWFLNGEPM--SASSRVKMINDFGWVIMDIAQTEPRDSGEWKCVAKNAAGE 3265
Query: 189 RESAIATLKIHIKPYLI 205
S AT+++ K ++
Sbjct: 3266 AVST-ATIEVQGKEVIL 3281
Score = 40.3 bits (90), Expect = 0.008
Identities = 45/196 (22%), Positives = 71/196 (36%), Gaps = 20/196 (10%)
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPG--MSRDKYHATAVFDGV--------TVL 356
G C G P+P + W +G+ + P + D V V T
Sbjct: 32 GETIILECQLEGHPDPAIKWLKDGHNVSMCPDYRIEEDGLKHRLVIPQVQAADSGRFTAQ 91
Query: 357 TINDTDKNDSRNTIVCSAVNY---AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKS 413
N S ++C+ S V + PI +Q L +
Sbjct: 92 ASNSAGTKQSTCILICAPAPTPVPGAKSAVASPAPPQTPVGPSAPIFLKELRHQPLKPGA 151
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TLVLKDLDKSDSGTYTCV 468
F I P P I W G+ L QN+R + +D +L++ + D+G YT
Sbjct: 152 GVTFEGRVIAVPPPNIEWMKNGKPL-QNYRAKIEHDQKTGIISLIIPQMFNDDAGEYTIK 210
Query: 469 ASSRHGKYVWSGALLV 484
A++ HG+ + SGA L+
Sbjct: 211 ATNVHGEAI-SGAQLL 225
Score = 39.1 bits (87), Expect = 0.019
Identities = 28/125 (22%), Positives = 52/125 (41%), Gaps = 3/125 (2%)
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGD 228
D Q + I+ + SA+ + KP + T + G+ Q + G+
Sbjct: 270 DTDQGSVDMHWTISESETEPELSALDARGVGTKPIIRTPLRGLRLTEGTDAILQANIVGN 329
Query: 229 PLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADEGEYSCEAENSVGAVSASG 285
P P + W + + R+++ GS L++ V + G+Y+ +EN G V +S
Sbjct: 330 PKPRIQWLFNGRPLQVSGPRMQMTYKGSMAVLKISMVTTEEAGDYTVASENRFGKVESSA 389
Query: 286 YLTVY 290
+ VY
Sbjct: 390 RIEVY 394
Score = 37.9 bits (84), Expect = 0.043
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 9/74 (12%)
Query: 422 ICTPEPI------IAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSR 472
+C EPI + W G + ++R + TN+ TL++K L +D+G Y CVA++
Sbjct: 3741 VCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNV 3800
Query: 473 HGKYVWSGALLVDS 486
G G + V+S
Sbjct: 3801 KGSATSVGKIAVES 3814
Score = 37.1 bits (82), Expect = 0.076
Identities = 24/98 (24%), Positives = 43/98 (43%), Gaps = 4/98 (4%)
Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---S 256
+ P I D A G ++ +C++ G P P + W + +M ++ +DG
Sbjct: 16 VAPTFIRPLADKRAVVGETIILECQLEGHPDPAIKWLKDGHNVSM-CPDYRIEEDGLKHR 74
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
L + V AD G ++ +A NS G ++ L P+
Sbjct: 75 LVIPQVQAADSGRFTAQASNSAGTKQSTCILICAPAPT 112
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 391 SDDDRP--PPIITNGPSNQTLPIKS--MAVFPCTA--ICTPEPIIAWYFEGEALIQNHR- 443
SDDD PP+ T + T P+K C I P I W+ +G L+ R
Sbjct: 1984 SDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGSRI 2043
Query: 444 RNVTNDGTLVLKDLD--KSDSGTYTCVASSRHGK 475
R + + G + L+ L D+GTYTC A++ G+
Sbjct: 2044 RTIHDFGYVGLEFLHIHPEDTGTYTCKATNLIGE 2077
Score = 35.9 bits (79), Expect = 0.18
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F + + Q + EC G P P V W NG L +++ L +
Sbjct: 4099 QFTIPLRNLQVTENQPARFECAVT-GYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVS 4157
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI 198
+R +DAG IARN G S ATL I
Sbjct: 4158 KSRISDAGEVVAIARNTEGETIST-ATLDI 4186
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGA 481
P+ + WY G L + RR + ND LV DL + D+G Y+ V + G+ SG
Sbjct: 2552 PKTSVQWYLNGNPLSASSRRILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQ 2611
Query: 482 L 482
L
Sbjct: 2612 L 2612
Score = 35.5 bits (78), Expect = 0.23
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGEALIQNHRRNVTNDGTLV 453
PP I S +L A F T +P + W+ GE + + R + ND V
Sbjct: 3181 PPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMINDFGWV 3240
Query: 454 LKDL---DKSDSGTYTCVASSRHGKYVWSGALLV 484
+ D+ + DSG + CVA + G+ V + + V
Sbjct: 3241 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEV 3274
Score = 35.1 bits (77), Expect = 0.31
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 110 FRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI 167
F + S++ +G + LE L P P+ V W +G L + R L G +L I
Sbjct: 1067 FHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDI 1126
Query: 168 QDARQTDAGRYQCIARNAAGTRES 191
D+G Y C A N G E+
Sbjct: 1127 PQTSSNDSGLYSCRAFNKLGESEN 1150
Score = 35.1 bits (77), Expect = 0.31
Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT--LVLKDLDKSDSGTYTCVASSR 472
A F C P P + W+ G + HR + DG L + SD+G +A +
Sbjct: 4115 ARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDAGEVVAIARNT 4174
Query: 473 HGKYVWSGAL 482
G+ + + L
Sbjct: 4175 EGETISTATL 4184
Score = 34.7 bits (76), Expect = 0.40
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 13/109 (11%)
Query: 227 GDPLPDVLWRRSAGGGNMPLG-RVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVS 282
GDP V W + G +P R+ ++ +L + ++I AD GEY C A N G+ +
Sbjct: 3748 GDPTLRVQWEHN--GHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSAT 3805
Query: 283 ASGYLTV-----YDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTM 324
+ G + V D P + L + N+ G+ C T +P +
Sbjct: 3806 SVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRL 3854
Score = 34.3 bits (75), Expect = 0.53
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 3/87 (3%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV-VSDTHRSILPAGGLFFL 69
AP I D + L C+ G P PAI+W K G V + +R + GL
Sbjct: 17 APTFIRPLADKRAVVGETIILECQLEGHPDPAIKWLKDGHNVSMCPDYR--IEEDGLKHR 74
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARS 96
+D+G + +A+NS GT +S
Sbjct: 75 LVIPQVQAADSGRFTAQASNSAGTKQS 101
Score = 33.9 bits (74), Expect = 0.71
Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTL-VLK 455
PII L + A+ + P+P I W F G L + R +T G++ VLK
Sbjct: 303 PIIRTPLRGLRLTEGTDAILQANIVGNPKPRIQWLFNGRPLQVSGPRMQMTYKGSMAVLK 362
Query: 456 --DLDKSDSGTYTCVASSRHGKYVWSGALLVDSPIN 489
+ ++G YT + +R GK V S A + P++
Sbjct: 363 ISMVTTEEAGDYTVASENRFGK-VESSARIEVYPLS 397
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASS 471
A F C P+P I W+ +G+ L + R V +G L ++ +D+G Y VA +
Sbjct: 4588 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 4647
Query: 472 RHGK 475
G+
Sbjct: 4648 GVGE 4651
Score = 32.7 bits (71), Expect = 1.6
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 121 QGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177
+G+ + LEC + P + W ++GQ+L G D G +L I DAG
Sbjct: 1610 EGEPIHLECQVNPINDNSLKIIWLRDGQSLPH-GHRFRTFYDFGFVSLDILGFYAQDAGT 1668
Query: 178 YQCIARNAAGTRESAIATLK 197
Y C A N+ G E+ +AT++
Sbjct: 1669 YTCRAENSLGQAET-VATIR 1687
Score = 32.7 bits (71), Expect = 1.6
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGAL 482
+ W+ + + ++ HR T D DL + D+G Y CVA++RHG+ + S L
Sbjct: 3995 VEWFKDKKPVLLGHRFRSTLDFGFACLDLLYALPDDTGEYHCVATNRHGQTMISAKL 4051
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIR--WYKGGVLVVSDTHRSILPAGGL 66
+AP IE PLD + Q A + P +R W+K G +++ + G
Sbjct: 2389 DAPQFIE-PLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFGY 2447
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA 94
L H V D+GVY +A+N+ G A
Sbjct: 2448 ISLDIAH-TVPEDSGVYSVKASNAKGDA 2474
Score = 31.5 bits (68), Expect = 3.8
Identities = 18/61 (29%), Positives = 28/61 (45%), Gaps = 2/61 (3%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT--DAGRYQCIARNAAGTRES 191
G+P+P + W NG+ L G G V++ + T +AG Y + N G ES
Sbjct: 328 GNPKPRIQWLFNGRPLQVSGPRMQMTYKGSMAVLKISMVTTEEAGDYTVASENRFGKVES 387
Query: 192 A 192
+
Sbjct: 388 S 388
Score = 31.5 bits (68), Expect = 3.8
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 39 PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
P+ + W K G + + I G+ L + H DAGVY C NS+G A+S
Sbjct: 1220 PTLRVSWLKDGQPLPNANRIQIFQNFGVVSL-SLHPTYPEDAGVYTCVLFNSHGQAQS 1276
Score = 31.5 bits (68), Expect = 3.8
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 214 QTGSSVTFQCRVG--GDPLPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLD--NVILADE 267
+ G + +C+V D ++W R G ++P G R + D G + LD D
Sbjct: 1609 EEGEPIHLECQVNPINDNSLKIIWLRD--GQSLPHGHRFRTFYDFGFVSLDILGFYAQDA 1666
Query: 268 GEYSCEAENSVG 279
G Y+C AENS+G
Sbjct: 1667 GTYTCRAENSLG 1678
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKYVWSGALLVD 485
W F G L + R V ND V D+D DSG YT V + G+ S VD
Sbjct: 1897 WLFNGNPLKASSRYRVLNDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1954
Score = 31.5 bits (68), Expect = 3.8
Identities = 11/40 (27%), Positives = 19/40 (47%)
Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
D P + ++ G+ +F+ G PEPT+ W +G
Sbjct: 4796 DSPHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKG 4835
Score = 31.1 bits (67), Expect = 5.0
Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 117 KQSAQ-GDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDAR 171
K+ AQ G ++ LEC L P P V W +NGQ L SR D NL I
Sbjct: 2135 KEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPL--PEASRFMPARNFDYVNLDILALY 2192
Query: 172 QTDAGRYQCIARNAAG 187
D+G Y C A +A G
Sbjct: 2193 GEDSGVYTCKAVSAFG 2208
Score = 30.7 bits (66), Expect = 6.6
Identities = 30/114 (26%), Positives = 49/114 (42%), Gaps = 6/114 (5%)
Query: 14 IIEQPL-DVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGGLFFLRA 71
II PL + + A L G+P P I+W + G L VS + G + L+
Sbjct: 304 IIRTPLRGLRLTEGTDAILQANIVGNPKPRIQWLFNGRPLQVSGPRMQMTYKGSMAVLKI 363
Query: 72 THGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR--EEFRLEPESKQSAQGD 123
+ +AG Y + N +G S +A + V L +E R E + ++ + D
Sbjct: 364 SMVTT-EEAGDYTVASENRFGKVES-SARIEVYPLSVPDERRKENQLREQQERD 415
Score = 30.3 bits (65), Expect = 8.7
Identities = 31/136 (22%), Positives = 52/136 (38%), Gaps = 2/136 (1%)
Query: 54 SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE 113
S T ++LP L + THG ++ + + + + + EFR +
Sbjct: 3908 SKTKITVLPRPSLDYTSQTHGNQQDSLESHFKQHSQAKLQLTANDIYNESDKRAPEFRTQ 3967
Query: 114 PESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDAR 171
++ +G+ E + P P V W K+ + +L R L G L + A
Sbjct: 3968 LQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACLDLLYAL 4027
Query: 172 QTDAGRYQCIARNAAG 187
D G Y C+A N G
Sbjct: 4028 PDDTGEYHCVATNRHG 4043
>AB026846-1|BAA90302.2| 4219|Caenorhabditis elegans kettin protein.
Length = 4219
Score = 77.4 bits (182), Expect = 6e-14
Identities = 84/325 (25%), Positives = 132/325 (40%), Gaps = 45/325 (13%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
T G+AP + D+ + ++ PA +C+ GG P P I+W+K G + +D ++ GG
Sbjct: 3896 TQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGA 3955
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-----EEFRLEPESKQSAQ 121
+ L+ ++ + +DAG+Y A N G AR + A L+V + + EE + ++Q
Sbjct: 3956 YKLKFSN-IISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGKGAEEGPRYEAPRFTSQ 4013
Query: 122 GDTVVLE-------CLPPRGSPEPNVYWKKNGQTLLF-DGDSRMHLVDGGNLVIQDARQT 173
+V++ G P+P + W +N + + DG L I AR
Sbjct: 4014 IQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSKGEAILRISAARNE 4073
Query: 174 D-----------AGRYQCIARNAAGTRESAIATLKIHI---------------KPYLITG 207
D AG+ +A R IA I P+ I
Sbjct: 4074 DVAEYKVEASNPAGKASSVANLVLTPRSGRIAKSTISRGGSASYQSSDKAAADSPHFIAK 4133
Query: 208 PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVIL 264
D+ A+ G +V F V G+P P V W + G VK+ DG L L V
Sbjct: 4134 LSDISARQGHTVKFSAEVDGNPEPTVQW-QFKGKPISASNNVKISRDGKRAILELARVTP 4192
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV 289
GEY N GA ++ LT+
Sbjct: 4193 DSAGEYQIVIRNDKGAATSQAKLTL 4217
Score = 62.1 bits (144), Expect = 2e-09
Identities = 57/218 (26%), Positives = 90/218 (41%), Gaps = 28/218 (12%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
G+ V W K+G+ + + + +L I + AG Y NAAGT ES
Sbjct: 3827 GAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVES- 3885
Query: 193 IATLKIHIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+A L + P+ D+ Q F C++GG+P P + W + G +P
Sbjct: 3886 LANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKD--GQPLPN 3943
Query: 247 -GRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV------------- 289
R +V+++G L+ N+I D G Y A+N VG L V
Sbjct: 3944 DDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 4003
Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
Y+ P + V+ G A+F+ +G P+PT+ W
Sbjct: 4004 RYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRW 4041
Score = 53.2 bits (122), Expect = 1e-06
Identities = 73/294 (24%), Positives = 114/294 (38%), Gaps = 34/294 (11%)
Query: 35 AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH-GRV-HSDAGVYWCEATNSYG 92
AG +P + W K G + S T R+++ + H GR+ +S AG Y N+ G
Sbjct: 3826 AGAAPVK-VTWLKDGKEIKS-TFRTLITTTPTN--SSLHIGRLENSHAGEYTVRLENAAG 3881
Query: 93 TARS-RNATLHVAVLR---EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T S N T+ + +F + Q C G P+P + W K+GQ
Sbjct: 3882 TVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSC-QIGGEPKPTIQWFKDGQP 3940
Query: 149 LLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---- 201
L D R +V+ G L + TDAG Y+ +A+N G A L ++++
Sbjct: 3941 L--PNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGK 3997
Query: 202 ----------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + + +V G F + G P P + W R+ G
Sbjct: 3998 GAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEIS 4057
Query: 252 LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
G LR+ D EY EA N G S+ L V P S ++ ++++
Sbjct: 4058 QSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANL-VLTPRSGRIAKSTIS 4110
Score = 52.8 bits (121), Expect = 1e-06
Identities = 53/193 (27%), Positives = 79/193 (40%), Gaps = 16/193 (8%)
Query: 118 QSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDA 175
Q + D C L P G P V W+ NG + + S + L+I+ DA
Sbjct: 3025 QLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADA 3084
Query: 176 GRYQCIARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQ--TGSSVTFQCRVG--G 227
G Y+C+A N G+ S A+ + P ++ D V G S+ +CRV
Sbjct: 3085 GEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPIN 3144
Query: 228 DPLPDVLWRRSAGGGNMP-LGRVK-VLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSA 283
DP V W R+ G +P R K + G + LD + D G+Y N G +
Sbjct: 3145 DPRLHVEWLRN--GAPLPEASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3202
Query: 284 SGYLTVYDPPSIN 296
+TV PS++
Sbjct: 3203 KTKITVLPRPSLD 3215
Score = 46.8 bits (106), Expect = 9e-05
Identities = 70/281 (24%), Positives = 116/281 (41%), Gaps = 34/281 (12%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLRL 259
P + P+ V A+ +VTF +V G P P + W++S G G+ K+ + DGS RL
Sbjct: 68 PQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 127
Query: 260 --DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT 317
+ V D Y A N G+ +S L N+ ++ G R C AT
Sbjct: 128 IIEKVDAHDADMYMLVARNDGGSFQSS---VDNKGNETTLHINNATMKEGGWYR--CDAT 182
Query: 318 GRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY 377
+ T +++G R ++ SR K++ A + ++T+ DK + T V +
Sbjct: 183 NKHGTT---TLKG-RVVV---NSRQKFNGPAHRE---MITLRKVDKVERSRTPVNQLQDV 232
Query: 378 AGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEA 437
+ S K + + + G S + L IK T + P IAW G+
Sbjct: 233 SAS-----KSSPKFEGSLQSQQLVEGQSAR-LEIK------YTPVEDPNLRIAWLLNGKG 280
Query: 438 LIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSRHGK 475
++ + R D L + ++ D G YT VA + G+
Sbjct: 281 ILASSRIVTFTDFGIAALEINPVNVFDQGEYTVVAVNPLGE 321
Score = 46.0 bits (104), Expect = 2e-04
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP------NSVNVESG 307
+ SL + + + GEY+ EN+ G V + LTV P + +P N + ++
Sbjct: 3856 NSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQN 3915
Query: 308 NVARFTCTATGRPEPTMFWSVEG 330
A F+C G P+PT+ W +G
Sbjct: 3916 GPAEFSCQIGGEPKPTIQWFKDG 3938
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/162 (26%), Positives = 67/162 (41%), Gaps = 8/162 (4%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P+ ++W G + S G+ L H + +DAG Y C ATN G+A S
Sbjct: 3042 GDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKH-LIAADAGEYKCVATNVKGSATS 3100
Query: 97 -----RNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLL 150
++ + + +L + +GD++ LEC + P P +V W +NG L
Sbjct: 3101 VGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLP 3160
Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRES 191
+ G +L I A D G Y+ + RN G S
Sbjct: 3161 EASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3202
Score = 42.7 bits (96), Expect = 0.002
Identities = 57/216 (26%), Positives = 86/216 (39%), Gaps = 18/216 (8%)
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTAT--GRPEPTMFW 326
++ A S GA + +G T D P+ + S V G T P+ + W
Sbjct: 345 QFGGTAYQSKGAQAPAG--THLDLPNFHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVW 402
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGK 386
++GN P S DKY T + G L I T NDS C A N G S +
Sbjct: 403 LLDGNE---LP--SNDKYRQT-LSHGFASLDIPQTSSNDS-GLYSCRAFNKLGESENQAT 455
Query: 387 LTVT--SDDDRPPPIITN-GPSNQTLPI-KSMAVFPCTAICTPEPIIAWYFEGEALIQNH 442
+ + S D P ++ P + + +S I P ++W +G+ L +
Sbjct: 456 IIIFAHSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQPINDPTLRVSWLKDGQPLPNAN 515
Query: 443 RRNV-TNDG--TLVLKDLDKSDSGTYTCVASSRHGK 475
R + N G +L L D+G YTCV + HG+
Sbjct: 516 RIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQ 551
Score = 42.7 bits (96), Expect = 0.002
Identities = 53/194 (27%), Positives = 79/194 (40%), Gaps = 18/194 (9%)
Query: 110 FRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI 167
F + S++ +G + LE L P P+ V W +G L + R L G +L I
Sbjct: 369 FHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDI 428
Query: 168 QDARQTDAGRYQCIARNAAGTRES-AIATLKIH----IKPYLITG--PEDVVAQTGSSVT 220
D+G Y C A N G E+ A + H + P ++ P + G S
Sbjct: 429 PQTSSNDSGLYSCRAFNKLGESENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELGRSF- 487
Query: 221 FQCRVG--GDPLPDVLWRRSAGGGNMP-LGRVKVLDDG---SLRLDNVILADEGEYSCEA 274
F+ R+ DP V W + G +P R+++ + SL L D G Y+C
Sbjct: 488 FEARIQPINDPTLRVSWLKD--GQPLPNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVL 545
Query: 275 ENSVGAVSASGYLT 288
NS G +S LT
Sbjct: 546 FNSHGQAQSSAELT 559
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 8/102 (7%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P + ++ V ARF C TG P P + W + GN+ + + FDG
Sbjct: 3392 PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCL-------HGHRFKLNFDG 3444
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
+ LT++ + +D+ +V A N G + L + +DD
Sbjct: 3445 LHYLTVSKSRISDA-GEVVAIARNTEGETISTATLDIFQNDD 3485
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 4/102 (3%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP ++ V +QPA C G P P + W+ G + HR L GL +L
Sbjct: 3390 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHG-HRFKLNFDGLHYL 3448
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
+ R+ SDAG A N+ G S ATL + ++FR
Sbjct: 3449 TVSKSRI-SDAGEVVAIARNTEGETIS-TATLDI-FQNDDFR 3487
Score = 41.5 bits (93), Expect = 0.004
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 392 DDDRPPPIITNGPSNQT-LPIKSMAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTN 448
D D PP T+ + L A C T + P +I W+ G+ + +R +
Sbjct: 2872 DADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIH 2931
Query: 449 D-GTLVLK--DLDKSDSGTYTCVASSRHG 474
D G +VL+ + DSGT+TC A+++HG
Sbjct: 2932 DFGFVVLQLTPAEPQDSGTWTCRATNQHG 2960
Score = 41.1 bits (92), Expect = 0.005
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGT 188
P P + W NG+ + SR+ +++ VI D QT D+G ++C+A+NAAG
Sbjct: 2502 PVDDPTLTINWFLNGEPM--SASSRVKMINDFGWVIMDIAQTEPRDSGEWKCVAKNAAGE 2559
Query: 189 RESAIATLKIHIKPYLI 205
S AT+++ K ++
Sbjct: 2560 AVST-ATIEVQGKEVIL 2575
Score = 39.9 bits (89), Expect = 0.011
Identities = 25/88 (28%), Positives = 45/88 (51%), Gaps = 4/88 (4%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDG-GNL 165
+F + P+S + +TV G+P P++ W+K+ T++ G + DG G L
Sbjct: 69 QFLVHPQSVAAKAFETVTFSAKVV-GTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 127
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAI 193
+I+ DA Y +ARN G+ +S++
Sbjct: 128 IIEKVDAHDADMYMLVARNDGGSFQSSV 155
Score = 37.9 bits (84), Expect = 0.043
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 9/74 (12%)
Query: 422 ICTPEPI------IAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSR 472
+C EPI + W G + ++R + TN+ TL++K L +D+G Y CVA++
Sbjct: 3035 VCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNV 3094
Query: 473 HGKYVWSGALLVDS 486
G G + V+S
Sbjct: 3095 KGSATSVGKIAVES 3108
Score = 35.9 bits (79), Expect = 0.18
Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 11/124 (8%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEF------RLEPESKQSAQGDTVVLECLP 131
+D+G+Y C A N G + ++ + A ++ +++P + G + +
Sbjct: 434 NDSGLYSCRAFNKLGESENQATIIIFAHSSQDLTPKFLSQIQPFHCEQELGRSFFEARIQ 493
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGT 188
P P V W K+GQ L +R+ + +V T DAG Y C+ N+ G
Sbjct: 494 PINDPTLRVSWLKDGQPL--PNANRIQIFQNFGVVSLSLHPTYPEDAGVYTCVLFNSHGQ 551
Query: 189 RESA 192
+S+
Sbjct: 552 AQSS 555
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 391 SDDDRP--PPIITNGPSNQTLPIKS--MAVFPCTA--ICTPEPIIAWYFEGEALIQNHR- 443
SDDD PP+ T + T P+K C I P I W+ +G L+ R
Sbjct: 1278 SDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGSRI 1337
Query: 444 RNVTNDGTLVLKDLD--KSDSGTYTCVASSRHGK 475
R + + G + L+ L D+GTYTC A++ G+
Sbjct: 1338 RTIHDFGYVGLEFLHIHPEDTGTYTCKATNLIGE 1371
Score = 35.9 bits (79), Expect = 0.18
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F + + Q + EC G P P V W NG L +++ L +
Sbjct: 3393 QFTIPLRNLQVTENQPARFECAVT-GYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVS 3451
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI 198
+R +DAG IARN G S ATL I
Sbjct: 3452 KSRISDAGEVVAIARNTEGETIST-ATLDI 3480
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGA 481
P+ + WY G L + RR + ND LV DL + D+G Y+ V + G+ SG
Sbjct: 1846 PKTSVQWYLNGNPLSASSRRILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQ 1905
Query: 482 L 482
L
Sbjct: 1906 L 1906
Score = 35.5 bits (78), Expect = 0.23
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGEALIQNHRRNVTNDGTLV 453
PP I S +L A F T +P + W+ GE + + R + ND V
Sbjct: 2475 PPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMINDFGWV 2534
Query: 454 LKDL---DKSDSGTYTCVASSRHGKYVWSGALLV 484
+ D+ + DSG + CVA + G+ V + + V
Sbjct: 2535 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEV 2568
Score = 35.1 bits (77), Expect = 0.31
Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT--LVLKDLDKSDSGTYTCVASSR 472
A F C P P + W+ G + HR + DG L + SD+G +A +
Sbjct: 3409 ARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDAGEVVAIARNT 3468
Query: 473 HGKYVWSGAL 482
G+ + + L
Sbjct: 3469 EGETISTATL 3478
Score = 34.7 bits (76), Expect = 0.40
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 13/109 (11%)
Query: 227 GDPLPDVLWRRSAGGGNMPLG-RVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVS 282
GDP V W + G +P R+ ++ +L + ++I AD GEY C A N G+ +
Sbjct: 3042 GDPTLRVQWEHN--GHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSAT 3099
Query: 283 ASGYLTV-----YDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTM 324
+ G + V D P + L + N+ G+ C T +P +
Sbjct: 3100 SVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRL 3148
Score = 33.5 bits (73), Expect = 0.93
Identities = 26/83 (31%), Positives = 40/83 (48%), Gaps = 5/83 (6%)
Query: 118 QSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTD 174
Q +G+ + LEC + P + W ++GQ+L G D G +L I D
Sbjct: 901 QVEEGEPIHLECQVNPINDNSLKIIWLRDGQSLPH-GHRFRTFYDFGFVSLDILGFYAQD 959
Query: 175 AGRYQCIARNAAGTRESAIATLK 197
AG Y C A N+ G E+ +AT++
Sbjct: 960 AGTYTCRAENSLGQAET-VATIR 981
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASS 471
A F C P+P I W+ +G+ L + R V +G L ++ +D+G Y VA +
Sbjct: 3918 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 3977
Query: 472 RHGK 475
G+
Sbjct: 3978 GVGE 3981
Score = 32.7 bits (71), Expect = 1.6
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGAL 482
+ W+ + + ++ HR T D DL + D+G Y CVA++RHG+ + S L
Sbjct: 3289 VEWFKDKKPVLLGHRFRSTLDFGFACLDLLYALPDDTGEYHCVATNRHGQTMISAKL 3345
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIR--WYKGGVLVVSDTHRSILPAGGL 66
+AP IE PLD + Q A + P +R W+K G +++ + G
Sbjct: 1683 DAPQFIE-PLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFGY 1741
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA 94
L H V D+GVY +A+N+ G A
Sbjct: 1742 ISLDIAH-TVPEDSGVYSVKASNAKGDA 1768
Score = 31.9 bits (69), Expect = 2.9
Identities = 21/75 (28%), Positives = 32/75 (42%), Gaps = 4/75 (5%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP + P SV ++ F+ G P P++ W + + T+I S KY D
Sbjct: 67 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQ-KSDGTVI---QSGGKYKIENGPD 122
Query: 352 GVTVLTINDTDKNDS 366
G L I D +D+
Sbjct: 123 GSGRLIIEKVDAHDA 137
Score = 31.5 bits (68), Expect = 3.8
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 39 PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
P+ + W K G + + I G+ L + H DAGVY C NS+G A+S
Sbjct: 498 PTLRVSWLKDGQPLPNANRIQIFQNFGVVSL-SLHPTYPEDAGVYTCVLFNSHGQAQS 554
Score = 31.5 bits (68), Expect = 3.8
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 214 QTGSSVTFQCRVG--GDPLPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLD--NVILADE 267
+ G + +C+V D ++W R G ++P G R + D G + LD D
Sbjct: 903 EEGEPIHLECQVNPINDNSLKIIWLRD--GQSLPHGHRFRTFYDFGFVSLDILGFYAQDA 960
Query: 268 GEYSCEAENSVG 279
G Y+C AENS+G
Sbjct: 961 GTYTCRAENSLG 972
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKYVWSGALLVD 485
W F G L + R V ND V D+D DSG YT V + G+ S VD
Sbjct: 1191 WLFNGNPLKASSRYRVLNDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1248
Score = 31.5 bits (68), Expect = 3.8
Identities = 11/40 (27%), Positives = 19/40 (47%)
Query: 291 DPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEG 330
D P + ++ G+ +F+ G PEPT+ W +G
Sbjct: 4126 DSPHFIAKLSDISARQGHTVKFSAEVDGNPEPTVQWQFKG 4165
Score = 31.1 bits (67), Expect = 5.0
Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 117 KQSAQ-GDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDAR 171
K+ AQ G ++ LEC L P P V W +NGQ L SR D NL I
Sbjct: 1429 KEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPL--PEASRFMPARNFDYVNLDILALY 1486
Query: 172 QTDAGRYQCIARNAAG 187
D+G Y C A +A G
Sbjct: 1487 GEDSGVYTCKAVSAFG 1502
Score = 30.7 bits (66), Expect = 6.6
Identities = 20/87 (22%), Positives = 36/87 (41%), Gaps = 6/87 (6%)
Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-HRRNVTN----D 449
RPP + + P + F + TP P + W +IQ+ + + N
Sbjct: 66 RPPQFLVH-PQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGS 124
Query: 450 GTLVLKDLDKSDSGTYTCVASSRHGKY 476
G L+++ +D D+ Y VA + G +
Sbjct: 125 GRLIIEKVDAHDADMYMLVARNDGGSF 151
Score = 30.3 bits (65), Expect = 8.7
Identities = 20/92 (21%), Positives = 38/92 (41%), Gaps = 1/92 (1%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+ + P + P V + T + + G+P+P++ W K V+ + + G
Sbjct: 62 LVNARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGP 121
Query: 66 LFFLRATHGRVHS-DAGVYWCEATNSYGTARS 96
R +V + DA +Y A N G+ +S
Sbjct: 122 DGSGRLIIEKVDAHDADMYMLVARNDGGSFQS 153
Score = 30.3 bits (65), Expect = 8.7
Identities = 13/42 (30%), Positives = 23/42 (54%)
Query: 445 NVTNDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
N N+ TL + + + G Y C A+++HG G ++V+S
Sbjct: 157 NKGNETTLHINNATMKEGGWYRCDATNKHGTTTLKGRVVVNS 198
Score = 30.3 bits (65), Expect = 8.7
Identities = 31/136 (22%), Positives = 52/136 (38%), Gaps = 2/136 (1%)
Query: 54 SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE 113
S T ++LP L + THG ++ + + + + + EFR +
Sbjct: 3202 SKTKITVLPRPSLDYTSQTHGNQQDSLESHFKQHSQAKLQLTANDIYNESDKRAPEFRTQ 3261
Query: 114 PESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDAR 171
++ +G+ E + P P V W K+ + +L R L G L + A
Sbjct: 3262 LQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACLDLLYAL 3321
Query: 172 QTDAGRYQCIARNAAG 187
D G Y C+A N G
Sbjct: 3322 PDDTGEYHCVATNRHG 3337
>Z73899-13|CAM35841.1| 6629|Caenorhabditis elegans Hypothetical
protein ZK617.1c protein.
Length = 6629
Score = 76.6 bits (180), Expect = 1e-13
Identities = 86/324 (26%), Positives = 130/324 (40%), Gaps = 44/324 (13%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + +N E G F C +G P P W +G + ++ KY T + G
Sbjct: 5394 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRW-FKGCKELV----DTSKY--TLINKG 5446
Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLP 410
VL IND +D+ + C A N +G+ R L + T PP G Q
Sbjct: 5447 DKQVLIINDLTSDDA-DEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGE 5505
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTC 467
+ + P A P+ W +GE + N + ++T D TL + + + D G Y
Sbjct: 5506 TIELKI-PYKAY--PQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRV 5562
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
V + G SG + V V+ +P PP PI N+ D +V LSW
Sbjct: 5563 VVENSVGSD--SGTVNVT--------------VADVPEPPRFPIIENILDEAVILSWKPP 5606
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
G S + Y +E RE + G+ +P + T+ ++ L G Y F +
Sbjct: 5607 ALDGGSLVTNYTIE--KREAMGGSWSP---------CAKSRYTYTTIEGLRAGKQYEFRI 5655
Query: 588 RTENSHGLSGP-SPVSDSVTVGDD 610
EN HG S P P + + GD+
Sbjct: 5656 IAENKHGQSKPCEPTAPVLIPGDE 5679
Score = 73.7 bits (173), Expect = 7e-13
Identities = 52/192 (27%), Positives = 88/192 (45%), Gaps = 12/192 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SGE P I+ D+ + T C GSP P RW+KG +V + +++ G
Sbjct: 5390 SGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQ 5449
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDT 124
L + DA Y C ATNS GT RS A L + F + P+ ++ +G+T
Sbjct: 5450 VL-IINDLTSDDADEYTCRATNSSGT-RSTRANLRIKTKPRVF-IPPKYHGGYEAQKGET 5506
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCI 181
+ L+ +P + P+ W K+G+ + + +S+ + L I +A + D G Y+ +
Sbjct: 5507 IELK-IPYKAYPQGEARWTKDGEKI--ENNSKFSITTDDKFATLRISNASREDYGEYRVV 5563
Query: 182 ARNAAGTRESAI 193
N+ G+ +
Sbjct: 5564 VENSVGSDSGTV 5575
Score = 72.9 bits (171), Expect = 1e-12
Identities = 121/493 (24%), Positives = 190/493 (38%), Gaps = 72/493 (14%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G P P+V W NG+ + G+S+ + + + A + +G+Y A N GT +
Sbjct: 2176 GEPAPDVTWSFNGKGI---GESKAQIENEPYISRFALPKALRKQSGKYTITATNINGT-D 2231
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGGNM 244
S +K+ KP GP +V T + GG+P+ ++ + G +
Sbjct: 2232 SVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWV 2291
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT------VYDPPSINLS 298
P GR D +D++ D ++ +A NS G T +D P
Sbjct: 2292 PCGRS---GDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGR 2348
Query: 299 PNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH----ATAVFDGV 353
P + +S +V ++ + P + +E R KY A V G
Sbjct: 2349 PEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIE----------KRTKYGRWEPAITVPGGQ 2398
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPI 411
T T+ D N+ V AVN G S K + + P I + N T+
Sbjct: 2399 TTATVPDLTPNEEYEFRVV-AVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKA 2457
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTC 467
F P P + W++ I+N R N LV+K +++ DSGT+T
Sbjct: 2458 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTI 2517
Query: 468 VASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
A + +G+ + + ++D P +PN DVS + G VTL+W
Sbjct: 2518 KAVNANGEDEATVKINVIDKPTSPN----GPLDVSDVHG------------DHVTLNWRA 2561
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV-HQTHYVVKSLIPGITYMF 585
+ G I Y +E + +T SG WV A+ +T VV LIPG Y F
Sbjct: 2562 PDDDGGIPIENYVIEKY--DTASGR--------WVPAAKVAGDKTTAVVDGLIPGHEYKF 2611
Query: 586 IVRTENSHGLSGP 598
V N+ G S P
Sbjct: 2612 RVAAVNAEGESDP 2624
Score = 72.1 bits (169), Expect = 2e-12
Identities = 118/494 (23%), Positives = 170/494 (34%), Gaps = 39/494 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I +P V Q A CR S P + W+K + G + L
Sbjct: 6056 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGL-- 6113
Query: 72 THGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLEC 129
T RV D G Y A NSYGT + L+V E + EP E + A V E
Sbjct: 6114 TINRVKGDDKGEYTVRAKNSYGT-KEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVEEF 6172
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ---DARQTDAGRYQCIARNAA 186
R +P + + L N I+ D D R Q R+
Sbjct: 6173 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGV 6232
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+ E A + Y +T D+ V GG+P+P V R P
Sbjct: 6233 CSLEIFNARVD-DAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRVSSFR-------PR 6284
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVN 303
L G+ + AD S + S SA+ L + PS +
Sbjct: 6285 RAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSFTAQLSDSE 6344
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
E G A F+ +G+PEP + W G R S ++ A+ V G L I+D K
Sbjct: 6345 TEVGGSAEFSAAVSGQPEPLIEWLHNGERI----SESDSRFRASYV-AGKATLRISDAKK 6399
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD----------RPPPIITNGPSNQTLPIKS 413
+D +C A N AG R LTV D +T + +
Sbjct: 6400 SD-EGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGE 6458
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
F TPE ++ W G+ L + +++ DG + + D SD+G Y
Sbjct: 6459 SVTFEARVQGTPEEVL-WMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVR 6517
Query: 471 SRHGKYVWSGALLV 484
S+ V +L+V
Sbjct: 6518 SKGTNLVSVASLVV 6531
Score = 68.1 bits (159), Expect = 4e-11
Identities = 57/180 (31%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178
G V EC GSP P W K + L+ S+ L++ G+ L+I D DA Y
Sbjct: 5408 GRCVTFEC-EISGSPRPEYRWFKGCKELV--DTSKYTLINKGDKQVLIINDLTSDDADEY 5464
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLW 235
C A N++GTR S A L+I KP + P+ AQ G ++ + P + W
Sbjct: 5465 TCRATNSSGTR-STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARW 5523
Query: 236 RRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ DD +LR+ N D GEY ENSVG+ S + +TV D P
Sbjct: 5524 TKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVP 5583
Score = 67.3 bits (157), Expect = 6e-11
Identities = 63/206 (30%), Positives = 93/206 (45%), Gaps = 32/206 (15%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G PEP + W NG+ + + DSR ++ L I DA+++D G+Y C A N+AG +E
Sbjct: 6359 GQPEPLIEWLHNGERIS-ESDSRFRASYVAGKATLRISDAKKSDEGQYLCRASNSAG-QE 6416
Query: 191 SAIATLKIHIKPYLITGPE---------------DVVAQTGSSVTFQCRVGGDPLPDVLW 235
ATL + L+ G + G SVTF+ RV G P +VLW
Sbjct: 6417 QTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGESVTFEARVQGTP-EEVLW 6475
Query: 236 RRSAGGGNMPLG-RVKVLDDG---SLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTV- 289
R+ G + G + + DG S +++ +D G Y E + VS + + V
Sbjct: 6476 MRN--GQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVRSKGTNLVSVASLVVVG 6533
Query: 290 --YDPPSINLSPNSVNVESGNVARFT 313
DPP L P+SV+ G FT
Sbjct: 6534 EKADPPVTRL-PSSVSAPLGGSTAFT 6558
Score = 66.1 bits (154), Expect = 1e-10
Identities = 123/504 (24%), Positives = 191/504 (37%), Gaps = 63/504 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186
+P G P P V W + +G R+ L + LV++ + D+G + A NA
Sbjct: 2465 VPVSGEPAPTVTWHWPDNREIRNG-GRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNAN 2523
Query: 187 GTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRR--S 238
G E AT+KI++ KP GP DV G VT R GG P+ + + + +
Sbjct: 2524 GEDE---ATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDT 2580
Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDP--- 292
A G +P +V D + +D +I E ++ A N+ G + G DP
Sbjct: 2581 ASGRWVPAAKVAG-DKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDK 2639
Query: 293 PSINLSPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P +P + + +V + A P + VE F D H A
Sbjct: 2640 PGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDE--FSPFWNDVAHVPAGQT 2697
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
TV + + K + R A N AG + + PP+I S Q + +
Sbjct: 2698 NATVGNLKEGSKYEFR----IRAKNKAGLGDPSDSASAVAKARNVPPVIDRN-SIQEIKV 2752
Query: 412 KSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRNVTN-DG--TLVLKDLDKSDSGTYT 466
K+ F + P P I W FEG + + R + N DG +K +SD+GTY
Sbjct: 2753 KAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 2812
Query: 467 CVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
A + +G + V D P +P GP +T N+ L+W
Sbjct: 2813 IKAENENGTDTAEVKVTVLDHPSSPR-------------GP--LDVT-NIVKDGCDLAWK 2856
Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585
+ G + I Y +E ++ +G W T++ V L G Y F
Sbjct: 2857 EPEDDGGAEISHYVIE--KQDAATGR--------WTACGES-KDTNFHVDDLTQGHEYKF 2905
Query: 586 IVRTENSHGLSGPSPVSDSVTVGD 609
V+ N HG S P +++ D
Sbjct: 2906 RVKAVNRHGDSDPLEAREAIIAKD 2929
Score = 64.1 bits (149), Expect = 6e-10
Identities = 80/312 (25%), Positives = 116/312 (37%), Gaps = 45/312 (14%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + P A FTC A GRPEPT W G P SR ++ A+ DG
Sbjct: 5004 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRE---LPESSRYRFEAS---DG 5057
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
V TI + D+ V N GS L V + PP+I N LP
Sbjct: 5058 VYKFTIKEVWDIDAGEYTV-EVSNPYGSDTATANLVVQA-----PPVIEKDVPNTILPSG 5111
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEA-----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
+ YF G A L+ N + T+ + + D T
Sbjct: 5112 DLVRLKI------------YFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPA 5159
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQ 526
++ G+Y ++ + + F+ +V+ LP P P+ N+ ++ TLSW
Sbjct: 5160 LSVREAGRYEYT---VSNDSGEATTGFW--LNVTGLPEAPQGPLHISNIGPSTATLSWRP 5214
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
G S I Y VE + LS + WV + V +Y+V L Y F
Sbjct: 5215 PVTDGGSKITSYVVE---KRDLSKDE-------WVTVTSNVKDMNYIVTGLFENHEYEFR 5264
Query: 587 VRTENSHGLSGP 598
V +N +G+ P
Sbjct: 5265 VSAQNENGIGAP 5276
Score = 60.9 bits (141), Expect = 5e-09
Identities = 84/305 (27%), Positives = 118/305 (38%), Gaps = 30/305 (9%)
Query: 2 SDDYVT--SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHR 58
+DD T + E P Q D A + G P P I W G + SD+
Sbjct: 6322 ADDLKTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRF 6381
Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV------------AVL 106
G LR + + SD G Y C A+NS G ++R ATL V +
Sbjct: 6382 RASYVAGKATLRISDAK-KSDEGQYLCRASNSAGQEQTR-ATLTVKGDQPLLNGHAGQAV 6439
Query: 107 REEFRLEPE--SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
E R+ + G++V E +G+PE V W +NGQ L +GD DG
Sbjct: 6440 ESELRVTKHLGGEIVNNGESVTFEA-RVQGTPE-EVLWMRNGQELT-NGDKTSISQDGET 6496
Query: 165 L--VIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGSSV 219
L I A +DAG YQ R + GT ++A+L + P + P V A G S
Sbjct: 6497 LSFTINSADASDAGHYQLEVR-SKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGST 6555
Query: 220 TFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
F V W R + N + VK + L + NV D+G Y +
Sbjct: 6556 AFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKE 6615
Query: 278 VGAVS 282
A++
Sbjct: 6616 KKAIA 6620
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SG AP I+E P +VTV ++ A L C+ GSP+P RW+KG V+S + G
Sbjct: 447 SGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEH 506
Query: 68 FLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
+ + S D G Y N +GT + L + +FR + ++S G
Sbjct: 507 TVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTSDNGLDFRAMLKHRESQAG 562
Score = 56.0 bits (129), Expect = 2e-07
Identities = 83/317 (26%), Positives = 122/317 (38%), Gaps = 41/317 (12%)
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
++L V++G T T P+P + W+ EG + + D T
Sbjct: 3920 LDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLA----------GVETTDSQT 3969
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
L I T ++DS + AVN G + K+TV D+P P N T P S
Sbjct: 3970 KLVIPSTRRSDS-GPVKIKAVNPYGEAEANIKITVI---DKP-----GAPENITYPAVSR 4020
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
CT A +G A I ++ G+ + + SGT V HG
Sbjct: 4021 HT--CTLNWD-----APKDDGGAEIAGYKIEYQEVGSQIWDKVPGLISGTAYTVRGLEHG 4073
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVT--DTS-VTLSWSQNNKI 530
+ + + ++ + + + V P PP P T +T DT+ V+L+W+
Sbjct: 4074 QQ-YRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQVSLAWNPPRDD 4132
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
G S ILGY VE F + R W + V T +V L TY F VR
Sbjct: 4133 GGSPILGYVVERFEK---------RGGGDWAPVKMPMVKGTECIVPGLHENETYQFRVRA 4183
Query: 590 ENSHGLSGPSPVSDSVT 606
N+ G PS S+ VT
Sbjct: 4184 VNAAGHGEPSNGSEPVT 4200
Score = 54.0 bits (124), Expect = 6e-07
Identities = 114/486 (23%), Positives = 176/486 (36%), Gaps = 52/486 (10%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+P G P P + W G + D +++ DG ++ A ++D G Y A N GT
Sbjct: 2762 IPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENGT 2821
Query: 189 RESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGN 243
++A + + P GP DV + + G + ++ GG + V+ ++ A G
Sbjct: 2822 -DTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISHYVIEKQDAATGR 2880
Query: 244 MPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSP 299
G K D + +D++ E ++ +A N G + A + DP P
Sbjct: 2881 WTACGESK---DTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEAREAIIAKDPFDRADKP 2937
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ + + T P +EG + S D A V G T++
Sbjct: 2938 GTPEIVDWDKDHADLKWTP-PADDGGAPIEGY-LVEMRTPSGDWVPAVTVGAGELTATVD 2995
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+ V A+N AG S + V P I + Q + F
Sbjct: 2996 GLKPGQTYQFRV-KALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNF 3054
Query: 418 PCTAICTPEPIIAWYFEGEALIQN---HRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRH 473
P P I W+ G L H N T++ T L K ++DSG Y VA++
Sbjct: 3055 DVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNES 3114
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGS 532
GK + ++ NI +PG P P+ H ++T SV L W + G
Sbjct: 3115 GK--------DEHEVDVNI--------LDIPGAPEGPLRHKDITKESVVLKWDEPLDDGG 3158
Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
S I Y VE ++ G WV T V L G Y F V+ N
Sbjct: 3159 SPITNYVVE---KQEDGGR--------WVPCG-ETSDTSLKVNKLSEGHEYKFRVKAVNR 3206
Query: 593 HGLSGP 598
G S P
Sbjct: 3207 QGTSAP 3212
Score = 51.6 bits (118), Expect = 3e-06
Identities = 110/454 (24%), Positives = 173/454 (38%), Gaps = 65/454 (14%)
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI------KPYLITGPEDVVAQTGSSVT 220
+ R+ + ++ +A NAAG ++ + I I +P ++ PED
Sbjct: 4963 VDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAV 5022
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKV-LDDGSLR--LDNVILADEGEYSCEAEN 276
F C G P P W R+ G +P R + DG + + V D GEY+ E N
Sbjct: 5023 FTCEAVGRPEPTARWLRN--GRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSN 5080
Query: 277 SVGAVSASGYLTVYDPPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
G+ +A+ L V PP I PN++ + SG++ R +G + +++
Sbjct: 5081 PYGSDTATANLVVQAPPVIEKDVPNTI-LPSGDLVRLKIYFSG--------TAPFRHSLV 5131
Query: 336 FPGMSRDKYHAT---AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
D H T FD ++TI ++ + N +G + L VT
Sbjct: 5132 LNREEIDMDHPTIRIVEFDDHILITIPALSVREA-GRYEYTVSNDSGEATTGFWLNVTGL 5190
Query: 393 DDRP--PPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN- 448
+ P P I+N GPS TL + P T I ++ E L ++ VT+
Sbjct: 5191 PEAPQGPLHISNIGPSTATLSWRP----PVTD--GGSKITSYVVEKRDLSKDEWVTVTSN 5244
Query: 449 --DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPG 505
D ++ L ++ + A + +G GA LV + PI + F
Sbjct: 5245 VKDMNYIVTGLFENHEYEFRVSAQNENG----IGAPLVSEHPIIARLPF----------D 5290
Query: 506 PPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
PPT P+ + VTLSW + G + GY VE E +N
Sbjct: 5291 PPTSPLNLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPS---- 5346
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
+Y V +LI G Y + V N GLS
Sbjct: 5347 -----PPNNYNVPNLIDGRKYRYRVFAVNDAGLS 5375
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/209 (22%), Positives = 82/209 (39%), Gaps = 17/209 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P +++ D+ + G VTF+C + G P P+ W + + + +++ G L
Sbjct: 5394 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGC-KELVDTSKYTLINKGDKQVLI 5452
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCT 315
++++ D EY+C A NS G S L + P + + P + G
Sbjct: 5453 INDLTSDDADEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIP 5512
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
P+ W+ +G + + K+ T D L I++ + D V
Sbjct: 5513 YKAYPQGEARWTKDGEKI-----ENNSKFSIT-TDDKFATLRISNASREDYGEYRVV-VE 5565
Query: 376 NYAGSSFVRGKLTVTSDDDRPP--PIITN 402
N GS +TV +D PP PII N
Sbjct: 5566 NSVGSDSGTVNVTV-ADVPEPPRFPIIEN 5593
Score = 49.2 bits (112), Expect = 2e-05
Identities = 51/221 (23%), Positives = 81/221 (36%), Gaps = 10/221 (4%)
Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNL 165
R + ++PE V C G PEP W +NG+ L R DG
Sbjct: 5003 RPQIVVKPEDTAQPYNRRAVFTC-EAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKF 5061
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
I++ DAG Y N G+ ++A A L + P + + + +G V +
Sbjct: 5062 TIKEVWDIDAGEYTVEVSNPYGS-DTATANLVVQAPPVIEKDVPNTILPSGDLVRLKIYF 5120
Query: 226 GGD-PL-PDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVILADEGEYSCEAENSVGAVS 282
G P ++ R + P R+ DD L + + + + G Y N G +
Sbjct: 5121 SGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEAT 5180
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
+L V P P ++ N+ T T + RP T
Sbjct: 5181 TGFWLNVTGLPEAPQGPLHIS----NIGPSTATLSWRPPVT 5217
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 32/185 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVWSGA 481
P+PII + + +N R V N G +V+ +SD+G Y A++++GK
Sbjct: 4338 PKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCK-- 4395
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQV 540
++ F V PG PT PI ++ ++TLSW G +I Y V
Sbjct: 4396 ----------LNVF----VLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAITNYVV 4441
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E + T G+ WV + V T V++L Y F VR EN +G+ P
Sbjct: 4442 E---KRTPGGD--------WVTVGHPVGTT-LRVRNLDANTPYEFRVRAENQYGVGEPLE 4489
Query: 601 VSDSV 605
D++
Sbjct: 4490 TDDAI 4494
Score = 48.4 bits (110), Expect = 3e-05
Identities = 24/91 (26%), Positives = 51/91 (56%), Gaps = 4/91 (4%)
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVI 263
G +D+ + G ++ + + G+PLP+ LW + G +GRVK+ + ++++N +
Sbjct: 1272 GIKDLRLKVGETIKYDVPISGEPLPECLWVVN-GKPLKAVGRVKMSSERGKHIMKIENAV 1330
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
AD G+++ +NS G+ ++ +TV P+
Sbjct: 1331 RADSGKFTITLKNSSGSCDSTATVTVVGRPT 1361
Score = 47.6 bits (108), Expect = 5e-05
Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 12/181 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
G+T+ + +P G P P W NG+ L G +M G +++ I++A + D+G++
Sbjct: 1281 GETIKYD-VPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1339
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQ--CRVGGDPLPDVLWR 236
+N++G+ +S AT+ + +P GP D+ V G+++++ GGDPL +
Sbjct: 1340 TLKNSSGSCDST-ATVTVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVE 1398
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS--CEAENSVG---AVSASGYLTVYD 291
V +D + L L ++G Y +A N+ G +SA Y + D
Sbjct: 1399 AQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKD 1458
Query: 292 P 292
P
Sbjct: 1459 P 1459
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 7/100 (7%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVI 263
+ + + G++V ++ ++GG+P+P+V W + G + G +D L + + +
Sbjct: 1570 KSITVKAGATVRWEVKIGGEPIPEVKWFK--GNQQLENGIQLTIDTRKNEHTILCIPSAM 1627
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
+D GEY +NS GA LTV D PS P V+
Sbjct: 1628 RSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVS 1667
Score = 43.6 bits (98), Expect = 9e-04
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 6/97 (6%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLV 453
P T S+ + A F PEP+I W GE + ++ R V TL
Sbjct: 6334 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6393
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPI 488
+ D KSD G Y C AS+ G+ L V D P+
Sbjct: 6394 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPL 6430
Score = 42.7 bits (96), Expect = 0.002
Identities = 117/488 (23%), Positives = 174/488 (35%), Gaps = 59/488 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188
+P RG P P W N + + D R+ D V++ A + AG Y A NA+G+
Sbjct: 1880 VPVRGEPPPKKEWIFNEKPV-DDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGS 1938
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGG 242
+ ++ + + KP GP +V + +V GG P+ ++ A G
Sbjct: 1939 DKHSVEVIVLG-KPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATGR 1997
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+P GR + + N+ E ++ A N G S LT + L+ N
Sbjct: 1998 WVPCGRSETT---KTTVPNLQPGHEYKFRVRAVNKEG---ESDPLTT---NTAILAKNPY 2048
Query: 303 NVESGNVARFTCTATGRPEPTMFWSV--EGNRTI-IFPGMSRDK---YHATAVFDGVTVL 356
V G V + + + W+ +G I F +DK + V G
Sbjct: 2049 EV-PGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQKT 2107
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
K SA N AG+ V + P I S+ T+ + +
Sbjct: 2108 ATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGAT 2167
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASS 471
F P P + W F G+ I + + N+ L + SG YT A++
Sbjct: 2168 LKFIVHIDGEPAPDVTWSFNGKG-IGESKAQIENEPYISRFALPKALRKQSGKYTITATN 2226
Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKI 530
+G DS + NI V S P P PI +V + TL W
Sbjct: 2227 ING---------TDS-VTINI------KVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDD 2270
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G I Y++E T G WV R TH+ V SL G Y F V+
Sbjct: 2271 GGEPIEFYEIE--KMNTKDGI--------WVPCGRS-GDTHFTVDSLNKGDHYKFRVKAV 2319
Query: 591 NSHGLSGP 598
NS G S P
Sbjct: 2320 NSEGPSDP 2327
Score = 42.7 bits (96), Expect = 0.002
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ G P I+ +P D ++ A C A G P P RW + G + + + G+
Sbjct: 4999 SGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGV 5058
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGT 93
+ + T V DAG Y E +N YG+
Sbjct: 5059 Y--KFTIKEVWDIDAGEYTVEVSNPYGS 5084
Score = 41.5 bits (93), Expect = 0.004
Identities = 45/153 (29%), Positives = 66/153 (43%), Gaps = 15/153 (9%)
Query: 178 YQCIARNAAGTRESAIATLKIHI-----KPYLITG--PEDVVAQTGSSVTFQCRVGGDPL 230
++ A NAAG E ++ ++ I +P + G D++A G P
Sbjct: 4575 FRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPA 4634
Query: 231 PDVLWRRSAGGGNMPLGRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P V + + + RVKV D +L ++ L D G Y E ENS G+ SAS L
Sbjct: 4635 PKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQGSDSASIRL 4694
Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D P+ SP + VE ++A CT P
Sbjct: 4695 KVVDKPA---SPQHIRVE--DIAPDCCTLYWMP 4722
Score = 40.3 bits (90), Expect = 0.008
Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 18/147 (12%)
Query: 178 YQCIARNAAGTRE----SAIATLK-IHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDP 229
Y+ +A N AG + SA AT K +H P + G E V + G + P
Sbjct: 3887 YRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRV-KAGEPLVITIPFTASP 3945
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
PD+ W + G PL V+ D + L + + +D G +A N G A+ +T
Sbjct: 3946 QPDISWTKEGG---KPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKIT 4002
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCT 315
V D P +P ++ + V+R TCT
Sbjct: 4003 VIDKPG---APENITYPA--VSRHTCT 4024
Score = 39.9 bits (89), Expect = 0.011
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P P +T S L+W++ + G + I GY VE ++ L N+ R +
Sbjct: 4208 PGAPDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVE---KKKLGDNDWTRCN------ 4258
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
+ V T + VK+L Y F V NS G PS SD V +
Sbjct: 4259 DKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLI 4302
Score = 39.5 bits (88), Expect = 0.014
Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 6/127 (4%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCR-AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G + I D+TV + + AGG+P P I + G + + R+++
Sbjct: 4307 GRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIF-ENERTVVDVNPGE 4365
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESKQSAQGDTVV 126
+ T G SDAG Y ATN YG L+V VL + P Q D +
Sbjct: 4366 IVITTTGSKRSDAGPYKISATNKYG---KDTCKLNVFVLDAPGKPTGPIRATDIQADAMT 4422
Query: 127 LECLPPR 133
L PP+
Sbjct: 4423 LSWRPPK 4429
Score = 38.7 bits (86), Expect = 0.025
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 8/102 (7%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P P ++ TL W + G S I Y VE G W +
Sbjct: 4700 PASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGK--------WEKV 4751
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
+ V +Y V LI Y F VR E +G+S P ++D V
Sbjct: 4752 SSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVV 4793
Score = 38.7 bits (86), Expect = 0.025
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
+++ AP+ + + ++ L C G+P+P I W K G V D +
Sbjct: 6170 EEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDED-RVQVSF 6228
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G+ L + RV DAG Y ATN G
Sbjct: 6229 RSGVCSLEIFNARV-DDAGTYTVTATNDLG 6257
Score = 37.5 bits (83), Expect = 0.057
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I P +V V A TC +G P PT W +G+R +I G R K+
Sbjct: 451 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRW-FKGSREVISGG--RFKHITDGKEHT 507
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
V + + +++ T+ V+ S+ V KL VTSD+
Sbjct: 508 VALALLKCRSQDEGPYTLTIENVHGTDSADV--KLLVTSDN 546
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 11/111 (9%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P P P+ +VT S L+W G + I Y VE R+T + NT
Sbjct: 3710 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVVE--KRDTKT--NT----- 3760
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
WV ++ V T V L G Y F V EN+ G S + V D
Sbjct: 3761 -WVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKD 3810
Score = 36.7 bits (81), Expect = 0.10
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-----S 256
P ++ PE+V + C+V G P P W + + + GR K + DG +
Sbjct: 451 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGS-REVISGGRFKHITDGKEHTVA 509
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L L DEG Y+ EN G SA L V
Sbjct: 510 LALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 542
Score = 36.3 bits (80), Expect = 0.13
Identities = 72/307 (23%), Positives = 115/307 (37%), Gaps = 29/307 (9%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
ATL + + W+ G + + + + L R+ D G Y C
Sbjct: 802 ATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIE-DHGEYKCT-- 858
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T R + + +F + + + + D V L C + + P + W +NG+
Sbjct: 859 ----TKDDRTMAQLIVDAKNKFIVALKDTEVIEKDDVTLMC-QTKDTKTPGI-WFRNGKQ 912
Query: 149 L--LFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYL 204
+ + G +G + L I +A Y+ + AG R S + L+ +P L
Sbjct: 913 ISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEI---DQAGLRGSCNVTVLEAEKRPIL 969
Query: 205 ITGPEDVVAQTGS----SVTFQCRVG--GDPLPDVLWRRSAGGGNM-PLGRVKVLDD-GS 256
P+ + A+ G V FQ + GDP +L M L V + DD
Sbjct: 970 NWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVIIKDDVAE 1029
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV-ARFTCT 315
+ N LAD G+++ E NS G A L V D P P +E+ NV A
Sbjct: 1030 IVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKP----KPPKGPLETKNVTAEGLDL 1085
Query: 316 ATGRPEP 322
G P+P
Sbjct: 1086 VWGTPDP 1092
Score = 36.3 bits (80), Expect = 0.13
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLR 258
+P I P G S F CRV P V W + + +K + D L
Sbjct: 6055 QPRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGLT 6114
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ V D+GEY+ A+NS G +L V
Sbjct: 6115 INRVKGDDKGEYTVRAKNSYGTKEEIVFLNV 6145
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 12/102 (11%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P P + T L W G S I+GYQV+ R+T SG W+
Sbjct: 4801 VPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQY--RDTSSGR--------WIN 4849
Query: 563 IARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+ Q H V L + F + +N+ G S PSP S+
Sbjct: 4850 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSE 4891
Score = 35.1 bits (77), Expect = 0.31
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 11/100 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P + + ++W +K G + I Y VEV +T + W +
Sbjct: 1463 PGKPGRPEITDFDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDT----------KEWKEV 1512
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+RV T+ + L G Y F VR N G PS S+
Sbjct: 1513 -KRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSE 1551
Score = 35.1 bits (77), Expect = 0.31
Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 33/186 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P+ W + R +VTN T + + + D+G Y + + HGK
Sbjct: 3356 PAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYKIIVENEHGK------ 3409
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQV 540
N+ V +PG P P+ + TL+W G + +L Y V
Sbjct: 3410 ----DTAQCNV------TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIV 3459
Query: 541 EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
E SRG W + T V K L+PG Y F V+ N G S P
Sbjct: 3460 EKMD-----------TSRGTWQEVGTFPDCTAKVNK-LVPGKEYAFRVKAVNLQGESKPL 3507
Query: 600 PVSDSV 605
+ +
Sbjct: 3508 EAEEPI 3513
Score = 35.1 bits (77), Expect = 0.31
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P ++ ++TL W++ G + I GY +E RE S W
Sbjct: 4503 PGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIE--KREV--------GSTEWTKA 4552
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
A + T + V L P TY F V N+ G
Sbjct: 4553 AFGNILDTKHRVTGLTPKKTYEFRVAAYNAAG 4584
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/94 (27%), Positives = 32/94 (34%), Gaps = 5/94 (5%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TL 452
P I P N T+ A+ C +P P W+ +I R DG L
Sbjct: 451 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVAL 510
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
L D G YT + HG LLV S
Sbjct: 511 ALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTS 544
Score = 34.7 bits (76), Expect = 0.40
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 1/74 (1%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++ V Q +LN G P+P I W G V SD + G + SD
Sbjct: 2749 EIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRA-LRSD 2807
Query: 80 AGVYWCEATNSYGT 93
G Y +A N GT
Sbjct: 2808 TGTYIIKAENENGT 2821
Score = 34.7 bits (76), Expect = 0.40
Identities = 35/152 (23%), Positives = 61/152 (40%), Gaps = 15/152 (9%)
Query: 178 YQCIARNAAGTRESAIAT-----LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
++ IA NAAG + + T ++KP ++T + + G + + G P P
Sbjct: 3592 FRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPDPT 3651
Query: 233 VLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
W + G L ++D S+ + AD G Y + +N +G A +
Sbjct: 3652 ATW--TVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGEDEAIFEVI 3709
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D PS P +E +V + +C +P
Sbjct: 3710 VQDRPSAPEGP----LEVSDVTKDSCVLNWKP 3737
Score = 33.5 bits (73), Expect = 0.93
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 13/114 (11%)
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNVESGNVAR 311
+L ++N + D G+Y+CEA V LTV +PP +N PN+ + A
Sbjct: 656 TLIINNPEVDDTGKYTCEA----NGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAV 711
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
TC P + W G++ I G R AV G LTI + +++D
Sbjct: 712 LTC-KVNTPRAPLVW-YRGSKA-IQEGDPRFIIEKDAV--GRCTLTIKEVEEDD 760
Score = 32.7 bits (71), Expect = 1.6
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 12/100 (12%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P PP P+ T NVT + L W + + + Y +E+ +E SGN
Sbjct: 1062 VKDKPKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEM--QEGRSGN------- 1112
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
W + T + VK L Y F V+ N GLS P
Sbjct: 1113 -WAKVGE-TKGTDFKVKDLKEHGEYKFRVKALNECGLSDP 1150
Score = 32.3 bits (70), Expect = 2.2
Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 1/83 (1%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV + GG P P ++W+KG + + +I + + SD
Sbjct: 1572 ITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDV 1631
Query: 81 GVYWCEATNSYGTARSRNATLHV 103
G Y NS+G A A L V
Sbjct: 1632 GEYRLTVKNSHG-ADEEKANLTV 1653
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 11/101 (10%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P KP + + + W+ G + + GY VE + S W
Sbjct: 3521 VPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVE----------KKEKGSAIWTE 3570
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
A + T + +L PG+ Y F V N+ G S PS +D
Sbjct: 3571 -AGKTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTD 3610
Score = 32.3 bits (70), Expect = 2.2
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
+ D P P +E+ + + L W PP+ +G N VV D N + V ++
Sbjct: 3710 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPK---DDGGAEISNYVVEKRDTKTN-TWVPVS 3765
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
V TS+ + LT G Y ++ AE G
Sbjct: 3766 AFV-TGTSITVPKLTEGHEYEFRVMAENTFG 3795
Score = 31.9 bits (69), Expect = 2.9
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 12/94 (12%)
Query: 504 PGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
P P P+ +V + ++ LSW + G I Y+VE +T +G WV
Sbjct: 1657 PSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVE--KLDTATGR--------WVP 1706
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
A +V T + L G TY F V+ N G S
Sbjct: 1707 CA-KVKDTKAHIDGLKKGQTYQFRVKAVNKEGAS 1739
Score = 31.1 bits (67), Expect = 5.0
Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 11/111 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PGPP ++ T++W + G S I GY VE+ RE S W V
Sbjct: 4902 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEI--RE--------YGSTLWTVA 4951
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ V + + V L Y F V N+ G PS S + + + S
Sbjct: 4952 SDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5002
Score = 30.3 bits (65), Expect = 8.7
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 11/123 (8%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD---DGSLRLD 260
+ G D+ + G+ + G+P P W+ A + G R V + ++ +
Sbjct: 3332 LAGLLDLRIKAGTPIKLDIAFEGEPAPVAKWK--ANDATIDTGARADVTNTPTSSAIHIF 3389
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ + D G Y EN G +A +TV D P P ++ + + CT +P
Sbjct: 3390 SAVRGDTGVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKID----EIHKEGCTLNWKP 3445
Query: 321 EPT 323
PT
Sbjct: 3446 -PT 3447
>Z73899-11|CAA98082.2| 7158|Caenorhabditis elegans Hypothetical
protein ZK617.1b protein.
Length = 7158
Score = 76.6 bits (180), Expect = 1e-13
Identities = 86/324 (26%), Positives = 130/324 (40%), Gaps = 44/324 (13%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + +N E G F C +G P P W +G + ++ KY T + G
Sbjct: 5923 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRW-FKGCKELV----DTSKY--TLINKG 5975
Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLP 410
VL IND +D+ + C A N +G+ R L + T PP G Q
Sbjct: 5976 DKQVLIINDLTSDDA-DEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGE 6034
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTC 467
+ + P A P+ W +GE + N + ++T D TL + + + D G Y
Sbjct: 6035 TIELKI-PYKAY--PQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRV 6091
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
V + G SG + V V+ +P PP PI N+ D +V LSW
Sbjct: 6092 VVENSVGSD--SGTVNVT--------------VADVPEPPRFPIIENILDEAVILSWKPP 6135
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
G S + Y +E RE + G+ +P + T+ ++ L G Y F +
Sbjct: 6136 ALDGGSLVTNYTIE--KREAMGGSWSP---------CAKSRYTYTTIEGLRAGKQYEFRI 6184
Query: 588 RTENSHGLSGP-SPVSDSVTVGDD 610
EN HG S P P + + GD+
Sbjct: 6185 IAENKHGQSKPCEPTAPVLIPGDE 6208
Score = 73.7 bits (173), Expect = 7e-13
Identities = 52/192 (27%), Positives = 88/192 (45%), Gaps = 12/192 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SGE P I+ D+ + T C GSP P RW+KG +V + +++ G
Sbjct: 5919 SGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQ 5978
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDT 124
L + DA Y C ATNS GT RS A L + F + P+ ++ +G+T
Sbjct: 5979 VL-IINDLTSDDADEYTCRATNSSGT-RSTRANLRIKTKPRVF-IPPKYHGGYEAQKGET 6035
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCI 181
+ L+ +P + P+ W K+G+ + + +S+ + L I +A + D G Y+ +
Sbjct: 6036 IELK-IPYKAYPQGEARWTKDGEKI--ENNSKFSITTDDKFATLRISNASREDYGEYRVV 6092
Query: 182 ARNAAGTRESAI 193
N+ G+ +
Sbjct: 6093 VENSVGSDSGTV 6104
Score = 72.9 bits (171), Expect = 1e-12
Identities = 121/493 (24%), Positives = 190/493 (38%), Gaps = 72/493 (14%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G P P+V W NG+ + G+S+ + + + A + +G+Y A N GT +
Sbjct: 2705 GEPAPDVTWSFNGKGI---GESKAQIENEPYISRFALPKALRKQSGKYTITATNINGT-D 2760
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGGNM 244
S +K+ KP GP +V T + GG+P+ ++ + G +
Sbjct: 2761 SVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWV 2820
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT------VYDPPSINLS 298
P GR D +D++ D ++ +A NS G T +D P
Sbjct: 2821 PCGRS---GDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGR 2877
Query: 299 PNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH----ATAVFDGV 353
P + +S +V ++ + P + +E R KY A V G
Sbjct: 2878 PEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIE----------KRTKYGRWEPAITVPGGQ 2927
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPI 411
T T+ D N+ V AVN G S K + + P I + N T+
Sbjct: 2928 TTATVPDLTPNEEYEFRVV-AVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKA 2986
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTC 467
F P P + W++ I+N R N LV+K +++ DSGT+T
Sbjct: 2987 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTI 3046
Query: 468 VASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
A + +G+ + + ++D P +PN DVS + G VTL+W
Sbjct: 3047 KAVNANGEDEATVKINVIDKPTSPN----GPLDVSDVHG------------DHVTLNWRA 3090
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV-HQTHYVVKSLIPGITYMF 585
+ G I Y +E + +T SG WV A+ +T VV LIPG Y F
Sbjct: 3091 PDDDGGIPIENYVIEKY--DTASGR--------WVPAAKVAGDKTTAVVDGLIPGHEYKF 3140
Query: 586 IVRTENSHGLSGP 598
V N+ G S P
Sbjct: 3141 RVAAVNAEGESDP 3153
Score = 72.1 bits (169), Expect = 2e-12
Identities = 118/494 (23%), Positives = 170/494 (34%), Gaps = 39/494 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I +P V Q A CR S P + W+K + G + L
Sbjct: 6585 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGL-- 6642
Query: 72 THGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLEC 129
T RV D G Y A NSYGT + L+V E + EP E + A V E
Sbjct: 6643 TINRVKGDDKGEYTVRAKNSYGT-KEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVEEF 6701
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ---DARQTDAGRYQCIARNAA 186
R +P + + L N I+ D D R Q R+
Sbjct: 6702 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGV 6761
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+ E A + Y +T D+ V GG+P+P V R P
Sbjct: 6762 CSLEIFNARVD-DAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRVSSFR-------PR 6813
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVN 303
L G+ + AD S + S SA+ L + PS +
Sbjct: 6814 RAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSFTAQLSDSE 6873
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
E G A F+ +G+PEP + W G R S ++ A+ V G L I+D K
Sbjct: 6874 TEVGGSAEFSAAVSGQPEPLIEWLHNGERI----SESDSRFRASYV-AGKATLRISDAKK 6928
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD----------RPPPIITNGPSNQTLPIKS 413
+D +C A N AG R LTV D +T + +
Sbjct: 6929 SD-EGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGE 6987
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
F TPE ++ W G+ L + +++ DG + + D SD+G Y
Sbjct: 6988 SVTFEARVQGTPEEVL-WMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVR 7046
Query: 471 SRHGKYVWSGALLV 484
S+ V +L+V
Sbjct: 7047 SKGTNLVSVASLVV 7060
Score = 68.1 bits (159), Expect = 4e-11
Identities = 57/180 (31%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178
G V EC GSP P W K + L+ S+ L++ G+ L+I D DA Y
Sbjct: 5937 GRCVTFEC-EISGSPRPEYRWFKGCKELV--DTSKYTLINKGDKQVLIINDLTSDDADEY 5993
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLW 235
C A N++GTR S A L+I KP + P+ AQ G ++ + P + W
Sbjct: 5994 TCRATNSSGTR-STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARW 6052
Query: 236 RRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ DD +LR+ N D GEY ENSVG+ S + +TV D P
Sbjct: 6053 TKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVP 6112
Score = 67.3 bits (157), Expect = 6e-11
Identities = 63/206 (30%), Positives = 93/206 (45%), Gaps = 32/206 (15%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G PEP + W NG+ + + DSR ++ L I DA+++D G+Y C A N+AG +E
Sbjct: 6888 GQPEPLIEWLHNGERIS-ESDSRFRASYVAGKATLRISDAKKSDEGQYLCRASNSAG-QE 6945
Query: 191 SAIATLKIHIKPYLITGPE---------------DVVAQTGSSVTFQCRVGGDPLPDVLW 235
ATL + L+ G + G SVTF+ RV G P +VLW
Sbjct: 6946 QTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGESVTFEARVQGTP-EEVLW 7004
Query: 236 RRSAGGGNMPLG-RVKVLDDG---SLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTV- 289
R+ G + G + + DG S +++ +D G Y E + VS + + V
Sbjct: 7005 MRN--GQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVRSKGTNLVSVASLVVVG 7062
Query: 290 --YDPPSINLSPNSVNVESGNVARFT 313
DPP L P+SV+ G FT
Sbjct: 7063 EKADPPVTRL-PSSVSAPLGGSTAFT 7087
Score = 66.1 bits (154), Expect = 1e-10
Identities = 123/504 (24%), Positives = 191/504 (37%), Gaps = 63/504 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186
+P G P P V W + +G R+ L + LV++ + D+G + A NA
Sbjct: 2994 VPVSGEPAPTVTWHWPDNREIRNG-GRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNAN 3052
Query: 187 GTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRR--S 238
G E AT+KI++ KP GP DV G VT R GG P+ + + + +
Sbjct: 3053 GEDE---ATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDT 3109
Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDP--- 292
A G +P +V D + +D +I E ++ A N+ G + G DP
Sbjct: 3110 ASGRWVPAAKVAG-DKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDK 3168
Query: 293 PSINLSPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P +P + + +V + A P + VE F D H A
Sbjct: 3169 PGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDE--FSPFWNDVAHVPAGQT 3226
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
TV + + K + R A N AG + + PP+I S Q + +
Sbjct: 3227 NATVGNLKEGSKYEFR----IRAKNKAGLGDPSDSASAVAKARNVPPVIDRN-SIQEIKV 3281
Query: 412 KSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRNVTN-DG--TLVLKDLDKSDSGTYT 466
K+ F + P P I W FEG + + R + N DG +K +SD+GTY
Sbjct: 3282 KAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 3341
Query: 467 CVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
A + +G + V D P +P GP +T N+ L+W
Sbjct: 3342 IKAENENGTDTAEVKVTVLDHPSSPR-------------GP--LDVT-NIVKDGCDLAWK 3385
Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585
+ G + I Y +E ++ +G W T++ V L G Y F
Sbjct: 3386 EPEDDGGAEISHYVIE--KQDAATGR--------WTACGES-KDTNFHVDDLTQGHEYKF 3434
Query: 586 IVRTENSHGLSGPSPVSDSVTVGD 609
V+ N HG S P +++ D
Sbjct: 3435 RVKAVNRHGDSDPLEAREAIIAKD 3458
Score = 64.1 bits (149), Expect = 6e-10
Identities = 80/312 (25%), Positives = 116/312 (37%), Gaps = 45/312 (14%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + P A FTC A GRPEPT W G P SR ++ A+ DG
Sbjct: 5533 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRE---LPESSRYRFEAS---DG 5586
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
V TI + D+ V N GS L V + PP+I N LP
Sbjct: 5587 VYKFTIKEVWDIDAGEYTV-EVSNPYGSDTATANLVVQA-----PPVIEKDVPNTILPSG 5640
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEA-----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
+ YF G A L+ N + T+ + + D T
Sbjct: 5641 DLVRLKI------------YFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPA 5688
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQ 526
++ G+Y ++ + + F+ +V+ LP P P+ N+ ++ TLSW
Sbjct: 5689 LSVREAGRYEYT---VSNDSGEATTGFW--LNVTGLPEAPQGPLHISNIGPSTATLSWRP 5743
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
G S I Y VE + LS + WV + V +Y+V L Y F
Sbjct: 5744 PVTDGGSKITSYVVE---KRDLSKDE-------WVTVTSNVKDMNYIVTGLFENHEYEFR 5793
Query: 587 VRTENSHGLSGP 598
V +N +G+ P
Sbjct: 5794 VSAQNENGIGAP 5805
Score = 60.9 bits (141), Expect = 5e-09
Identities = 84/305 (27%), Positives = 118/305 (38%), Gaps = 30/305 (9%)
Query: 2 SDDYVT--SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHR 58
+DD T + E P Q D A + G P P I W G + SD+
Sbjct: 6851 ADDLKTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRF 6910
Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV------------AVL 106
G LR + + SD G Y C A+NS G ++R ATL V +
Sbjct: 6911 RASYVAGKATLRISDAK-KSDEGQYLCRASNSAGQEQTR-ATLTVKGDQPLLNGHAGQAV 6968
Query: 107 REEFRLEPE--SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
E R+ + G++V E +G+PE V W +NGQ L +GD DG
Sbjct: 6969 ESELRVTKHLGGEIVNNGESVTFEA-RVQGTPE-EVLWMRNGQELT-NGDKTSISQDGET 7025
Query: 165 L--VIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGSSV 219
L I A +DAG YQ R + GT ++A+L + P + P V A G S
Sbjct: 7026 LSFTINSADASDAGHYQLEVR-SKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGST 7084
Query: 220 TFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
F V W R + N + VK + L + NV D+G Y +
Sbjct: 7085 AFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKE 7144
Query: 278 VGAVS 282
A++
Sbjct: 7145 KKAIA 7149
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SG AP I+E P +VTV ++ A L C+ GSP+P RW+KG V+S + G
Sbjct: 976 SGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEH 1035
Query: 68 FLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
+ + S D G Y N +GT + L + +FR + ++S G
Sbjct: 1036 TVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTSDNGLDFRAMLKHRESQAG 1091
Score = 56.0 bits (129), Expect = 2e-07
Identities = 83/317 (26%), Positives = 122/317 (38%), Gaps = 41/317 (12%)
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
++L V++G T T P+P + W+ EG + + D T
Sbjct: 4449 LDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLA----------GVETTDSQT 4498
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
L I T ++DS + AVN G + K+TV D+P P N T P S
Sbjct: 4499 KLVIPSTRRSDS-GPVKIKAVNPYGEAEANIKITVI---DKP-----GAPENITYPAVSR 4549
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
CT A +G A I ++ G+ + + SGT V HG
Sbjct: 4550 HT--CTLNWD-----APKDDGGAEIAGYKIEYQEVGSQIWDKVPGLISGTAYTVRGLEHG 4602
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVT--DTS-VTLSWSQNNKI 530
+ + + ++ + + + V P PP P T +T DT+ V+L+W+
Sbjct: 4603 QQ-YRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQVSLAWNPPRDD 4661
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
G S ILGY VE F + R W + V T +V L TY F VR
Sbjct: 4662 GGSPILGYVVERFEK---------RGGGDWAPVKMPMVKGTECIVPGLHENETYQFRVRA 4712
Query: 590 ENSHGLSGPSPVSDSVT 606
N+ G PS S+ VT
Sbjct: 4713 VNAAGHGEPSNGSEPVT 4729
Score = 54.0 bits (124), Expect = 6e-07
Identities = 114/486 (23%), Positives = 176/486 (36%), Gaps = 52/486 (10%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+P G P P + W G + D +++ DG ++ A ++D G Y A N GT
Sbjct: 3291 IPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENGT 3350
Query: 189 RESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGN 243
++A + + P GP DV + + G + ++ GG + V+ ++ A G
Sbjct: 3351 -DTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISHYVIEKQDAATGR 3409
Query: 244 MPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSP 299
G K D + +D++ E ++ +A N G + A + DP P
Sbjct: 3410 WTACGESK---DTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEAREAIIAKDPFDRADKP 3466
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ + + T P +EG + S D A V G T++
Sbjct: 3467 GTPEIVDWDKDHADLKWTP-PADDGGAPIEGY-LVEMRTPSGDWVPAVTVGAGELTATVD 3524
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+ V A+N AG S + V P I + Q + F
Sbjct: 3525 GLKPGQTYQFRV-KALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNF 3583
Query: 418 PCTAICTPEPIIAWYFEGEALIQN---HRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRH 473
P P I W+ G L H N T++ T L K ++DSG Y VA++
Sbjct: 3584 DVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNES 3643
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGS 532
GK + ++ NI +PG P P+ H ++T SV L W + G
Sbjct: 3644 GK--------DEHEVDVNI--------LDIPGAPEGPLRHKDITKESVVLKWDEPLDDGG 3687
Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
S I Y VE ++ G WV T V L G Y F V+ N
Sbjct: 3688 SPITNYVVE---KQEDGGR--------WVPCG-ETSDTSLKVNKLSEGHEYKFRVKAVNR 3735
Query: 593 HGLSGP 598
G S P
Sbjct: 3736 QGTSAP 3741
Score = 51.6 bits (118), Expect = 3e-06
Identities = 110/454 (24%), Positives = 173/454 (38%), Gaps = 65/454 (14%)
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI------KPYLITGPEDVVAQTGSSVT 220
+ R+ + ++ +A NAAG ++ + I I +P ++ PED
Sbjct: 5492 VDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAV 5551
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKV-LDDGSLR--LDNVILADEGEYSCEAEN 276
F C G P P W R+ G +P R + DG + + V D GEY+ E N
Sbjct: 5552 FTCEAVGRPEPTARWLRN--GRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSN 5609
Query: 277 SVGAVSASGYLTVYDPPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
G+ +A+ L V PP I PN++ + SG++ R +G + +++
Sbjct: 5610 PYGSDTATANLVVQAPPVIEKDVPNTI-LPSGDLVRLKIYFSG--------TAPFRHSLV 5660
Query: 336 FPGMSRDKYHAT---AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
D H T FD ++TI ++ + N +G + L VT
Sbjct: 5661 LNREEIDMDHPTIRIVEFDDHILITIPALSVREA-GRYEYTVSNDSGEATTGFWLNVTGL 5719
Query: 393 DDRP--PPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN- 448
+ P P I+N GPS TL + P T I ++ E L ++ VT+
Sbjct: 5720 PEAPQGPLHISNIGPSTATLSWRP----PVTD--GGSKITSYVVEKRDLSKDEWVTVTSN 5773
Query: 449 --DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPG 505
D ++ L ++ + A + +G GA LV + PI + F
Sbjct: 5774 VKDMNYIVTGLFENHEYEFRVSAQNENG----IGAPLVSEHPIIARLPF----------D 5819
Query: 506 PPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
PPT P+ + VTLSW + G + GY VE E +N
Sbjct: 5820 PPTSPLNLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPS---- 5875
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
+Y V +LI G Y + V N GLS
Sbjct: 5876 -----PPNNYNVPNLIDGRKYRYRVFAVNDAGLS 5904
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/209 (22%), Positives = 82/209 (39%), Gaps = 17/209 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P +++ D+ + G VTF+C + G P P+ W + + + +++ G L
Sbjct: 5923 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGC-KELVDTSKYTLINKGDKQVLI 5981
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCT 315
++++ D EY+C A NS G S L + P + + P + G
Sbjct: 5982 INDLTSDDADEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIP 6041
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
P+ W+ +G + + K+ T D L I++ + D V
Sbjct: 6042 YKAYPQGEARWTKDGEKI-----ENNSKFSIT-TDDKFATLRISNASREDYGEYRVV-VE 6094
Query: 376 NYAGSSFVRGKLTVTSDDDRPP--PIITN 402
N GS +TV +D PP PII N
Sbjct: 6095 NSVGSDSGTVNVTV-ADVPEPPRFPIIEN 6122
Score = 49.2 bits (112), Expect = 2e-05
Identities = 51/221 (23%), Positives = 81/221 (36%), Gaps = 10/221 (4%)
Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNL 165
R + ++PE V C G PEP W +NG+ L R DG
Sbjct: 5532 RPQIVVKPEDTAQPYNRRAVFTC-EAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKF 5590
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
I++ DAG Y N G+ ++A A L + P + + + +G V +
Sbjct: 5591 TIKEVWDIDAGEYTVEVSNPYGS-DTATANLVVQAPPVIEKDVPNTILPSGDLVRLKIYF 5649
Query: 226 GGD-PL-PDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVILADEGEYSCEAENSVGAVS 282
G P ++ R + P R+ DD L + + + + G Y N G +
Sbjct: 5650 SGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEAT 5709
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
+L V P P ++ N+ T T + RP T
Sbjct: 5710 TGFWLNVTGLPEAPQGPLHIS----NIGPSTATLSWRPPVT 5746
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 32/185 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVWSGA 481
P+PII + + +N R V N G +V+ +SD+G Y A++++GK
Sbjct: 4867 PKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCK-- 4924
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQV 540
++ F V PG PT PI ++ ++TLSW G +I Y V
Sbjct: 4925 ----------LNVF----VLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAITNYVV 4970
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E + T G+ WV + V T V++L Y F VR EN +G+ P
Sbjct: 4971 E---KRTPGGD--------WVTVGHPVGTT-LRVRNLDANTPYEFRVRAENQYGVGEPLE 5018
Query: 601 VSDSV 605
D++
Sbjct: 5019 TDDAI 5023
Score = 48.4 bits (110), Expect = 3e-05
Identities = 24/91 (26%), Positives = 51/91 (56%), Gaps = 4/91 (4%)
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVI 263
G +D+ + G ++ + + G+PLP+ LW + G +GRVK+ + ++++N +
Sbjct: 1801 GIKDLRLKVGETIKYDVPISGEPLPECLWVVN-GKPLKAVGRVKMSSERGKHIMKIENAV 1859
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
AD G+++ +NS G+ ++ +TV P+
Sbjct: 1860 RADSGKFTITLKNSSGSCDSTATVTVVGRPT 1890
Score = 47.6 bits (108), Expect = 5e-05
Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 12/181 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
G+T+ + +P G P P W NG+ L G +M G +++ I++A + D+G++
Sbjct: 1810 GETIKYD-VPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1868
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQ--CRVGGDPLPDVLWR 236
+N++G+ +S AT+ + +P GP D+ V G+++++ GGDPL +
Sbjct: 1869 TLKNSSGSCDST-ATVTVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVE 1927
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS--CEAENSVG---AVSASGYLTVYD 291
V +D + L L ++G Y +A N+ G +SA Y + D
Sbjct: 1928 AQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKD 1987
Query: 292 P 292
P
Sbjct: 1988 P 1988
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 7/100 (7%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVI 263
+ + + G++V ++ ++GG+P+P+V W + G + G +D L + + +
Sbjct: 2099 KSITVKAGATVRWEVKIGGEPIPEVKWFK--GNQQLENGIQLTIDTRKNEHTILCIPSAM 2156
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
+D GEY +NS GA LTV D PS P V+
Sbjct: 2157 RSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVS 2196
Score = 45.2 bits (102), Expect = 3e-04
Identities = 48/204 (23%), Positives = 78/204 (38%), Gaps = 23/204 (11%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNL--- 165
F +P +Q+ GD +++EC P+P + W+ +G L G L GG+L
Sbjct: 7 FTQKPSIQQTPTGD-LLMEC-HLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKA 64
Query: 166 --VIQDARQTDAGRYQCIARNAAGTRESAI--------ATLKIHIKPYLITGPEDVVAQT 215
VI++ D G Y+C ARN G + I P + P +
Sbjct: 65 TLVIKEPNAGDGGAYKCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKDG 124
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGS----LRLDNVILADEG 268
G+ + +C+V P W + G + L D + L + +D G
Sbjct: 125 GALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAG 184
Query: 269 EYSCEAENSVGAVSASGYLTVYDP 292
+Y C N G +A+ L +P
Sbjct: 185 QYRCNIRNDQGETNANLALNFEEP 208
Score = 43.6 bits (98), Expect = 9e-04
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 6/97 (6%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLV 453
P T S+ + A F PEP+I W GE + ++ R V TL
Sbjct: 6863 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6922
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPI 488
+ D KSD G Y C AS+ G+ L V D P+
Sbjct: 6923 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPL 6959
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/182 (24%), Positives = 70/182 (38%), Gaps = 20/182 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGLFFLRATHGRVHS--DAGVYWCE 86
+ C P P I W G L+ +++ P GG + + + D G Y C
Sbjct: 23 MECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKATLVIKEPNAGDGGAYKCT 82
Query: 87 ATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQGDTVVLECLPPRGSPEP 138
A N G + + N L+ A + F +P G +V+EC + + P
Sbjct: 83 ARNQLGESNA-NINLNFAGAGGDEAKSRGPSFVGKPRIIPKDGGALIVMEC-KVKSASTP 140
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGN------LVIQDARQTDAGRYQCIARNAAGTRESA 192
W K+G L G D G+ L I+ +DAG+Y+C RN G +
Sbjct: 141 VAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNAN 200
Query: 193 IA 194
+A
Sbjct: 201 LA 202
Score = 42.7 bits (96), Expect = 0.002
Identities = 117/488 (23%), Positives = 174/488 (35%), Gaps = 59/488 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188
+P RG P P W N + + D R+ D V++ A + AG Y A NA+G+
Sbjct: 2409 VPVRGEPPPKKEWIFNEKPV-DDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGS 2467
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGG 242
+ ++ + + KP GP +V + +V GG P+ ++ A G
Sbjct: 2468 DKHSVEVIVLG-KPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATGR 2526
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+P GR + + N+ E ++ A N G S LT + L+ N
Sbjct: 2527 WVPCGRSETT---KTTVPNLQPGHEYKFRVRAVNKEG---ESDPLTT---NTAILAKNPY 2577
Query: 303 NVESGNVARFTCTATGRPEPTMFWSV--EGNRTI-IFPGMSRDK---YHATAVFDGVTVL 356
V G V + + + W+ +G I F +DK + V G
Sbjct: 2578 EV-PGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQKT 2636
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
K SA N AG+ V + P I S+ T+ + +
Sbjct: 2637 ATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGAT 2696
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASS 471
F P P + W F G+ I + + N+ L + SG YT A++
Sbjct: 2697 LKFIVHIDGEPAPDVTWSFNGKG-IGESKAQIENEPYISRFALPKALRKQSGKYTITATN 2755
Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKI 530
+G DS + NI V S P P PI +V + TL W
Sbjct: 2756 ING---------TDS-VTINI------KVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDD 2799
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G I Y++E T G WV R TH+ V SL G Y F V+
Sbjct: 2800 GGEPIEFYEIE--KMNTKDGI--------WVPCGRS-GDTHFTVDSLNKGDHYKFRVKAV 2848
Query: 591 NSHGLSGP 598
NS G S P
Sbjct: 2849 NSEGPSDP 2856
Score = 42.7 bits (96), Expect = 0.002
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ G P I+ +P D ++ A C A G P P RW + G + + + G+
Sbjct: 5528 SGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGV 5587
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGT 93
+ + T V DAG Y E +N YG+
Sbjct: 5588 Y--KFTIKEVWDIDAGEYTVEVSNPYGS 5613
Score = 41.5 bits (93), Expect = 0.004
Identities = 45/153 (29%), Positives = 66/153 (43%), Gaps = 15/153 (9%)
Query: 178 YQCIARNAAGTRESAIATLKIHI-----KPYLITG--PEDVVAQTGSSVTFQCRVGGDPL 230
++ A NAAG E ++ ++ I +P + G D++A G P
Sbjct: 5104 FRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPA 5163
Query: 231 PDVLWRRSAGGGNMPLGRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P V + + + RVKV D +L ++ L D G Y E ENS G+ SAS L
Sbjct: 5164 PKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQGSDSASIRL 5223
Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D P+ SP + VE ++A CT P
Sbjct: 5224 KVVDKPA---SPQHIRVE--DIAPDCCTLYWMP 5251
Score = 40.3 bits (90), Expect = 0.008
Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 18/147 (12%)
Query: 178 YQCIARNAAGTRE----SAIATLK-IHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDP 229
Y+ +A N AG + SA AT K +H P + G E V + G + P
Sbjct: 4416 YRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRV-KAGEPLVITIPFTASP 4474
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
PD+ W + G PL V+ D + L + + +D G +A N G A+ +T
Sbjct: 4475 QPDISWTKEGG---KPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKIT 4531
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCT 315
V D P +P ++ + V+R TCT
Sbjct: 4532 VIDKPG---APENITYPA--VSRHTCT 4553
Score = 39.9 bits (89), Expect = 0.011
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P P +T S L+W++ + G + I GY VE ++ L N+ R +
Sbjct: 4737 PGAPDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVE---KKKLGDNDWTRCN------ 4787
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
+ V T + VK+L Y F V NS G PS SD V +
Sbjct: 4788 DKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLI 4831
Score = 39.5 bits (88), Expect = 0.014
Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 6/127 (4%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCR-AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G + I D+TV + + AGG+P P I + G + + R+++
Sbjct: 4836 GRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIF-ENERTVVDVNPGE 4894
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESKQSAQGDTVV 126
+ T G SDAG Y ATN YG L+V VL + P Q D +
Sbjct: 4895 IVITTTGSKRSDAGPYKISATNKYG---KDTCKLNVFVLDAPGKPTGPIRATDIQADAMT 4951
Query: 127 LECLPPR 133
L PP+
Sbjct: 4952 LSWRPPK 4958
Score = 38.7 bits (86), Expect = 0.025
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 8/102 (7%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P P ++ TL W + G S I Y VE G W +
Sbjct: 5229 PASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGK--------WEKV 5280
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
+ V +Y V LI Y F VR E +G+S P ++D V
Sbjct: 5281 SSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVV 5322
Score = 38.7 bits (86), Expect = 0.025
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
+++ AP+ + + ++ L C G+P+P I W K G V D +
Sbjct: 6699 EEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDED-RVQVSF 6757
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G+ L + RV DAG Y ATN G
Sbjct: 6758 RSGVCSLEIFNARV-DDAGTYTVTATNDLG 6786
Score = 37.9 bits (84), Expect = 0.043
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 9/86 (10%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR--RNVTNDG----- 450
P T PS Q P + + C P+P IAW G L + R + +T G
Sbjct: 5 PRFTQKPSIQQTPTGDL-LMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYK 63
Query: 451 -TLVLKDLDKSDSGTYTCVASSRHGK 475
TLV+K+ + D G Y C A ++ G+
Sbjct: 64 ATLVIKEPNAGDGGAYKCTARNQLGE 89
Score = 37.5 bits (83), Expect = 0.057
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I P +V V A TC +G P PT W +G+R +I G R K+
Sbjct: 980 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRW-FKGSREVISGG--RFKHITDGKEHT 1036
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
V + + +++ T+ V+ S+ V KL VTSD+
Sbjct: 1037 VALALLKCRSQDEGPYTLTIENVHGTDSADV--KLLVTSDN 1075
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 11/111 (9%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P P P+ +VT S L+W G + I Y VE R+T + NT
Sbjct: 4239 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVVE--KRDTKT--NT----- 4289
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
WV ++ V T V L G Y F V EN+ G S + V D
Sbjct: 4290 -WVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKD 4339
Score = 36.7 bits (81), Expect = 0.10
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-----S 256
P ++ PE+V + C+V G P P W + + + GR K + DG +
Sbjct: 980 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGS-REVISGGRFKHITDGKEHTVA 1038
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L L DEG Y+ EN G SA L V
Sbjct: 1039 LALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 1071
Score = 36.3 bits (80), Expect = 0.13
Identities = 72/307 (23%), Positives = 115/307 (37%), Gaps = 29/307 (9%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
ATL + + W+ G + + + + L R+ D G Y C
Sbjct: 1331 ATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIE-DHGEYKCT-- 1387
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T R + + +F + + + + D V L C + + P + W +NG+
Sbjct: 1388 ----TKDDRTMAQLIVDAKNKFIVALKDTEVIEKDDVTLMC-QTKDTKTPGI-WFRNGKQ 1441
Query: 149 L--LFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYL 204
+ + G +G + L I +A Y+ + AG R S + L+ +P L
Sbjct: 1442 ISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEI---DQAGLRGSCNVTVLEAEKRPIL 1498
Query: 205 ITGPEDVVAQTGS----SVTFQCRVG--GDPLPDVLWRRSAGGGNM-PLGRVKVLDD-GS 256
P+ + A+ G V FQ + GDP +L M L V + DD
Sbjct: 1499 NWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVIIKDDVAE 1558
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV-ARFTCT 315
+ N LAD G+++ E NS G A L V D P P +E+ NV A
Sbjct: 1559 IVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKP----KPPKGPLETKNVTAEGLDL 1614
Query: 316 ATGRPEP 322
G P+P
Sbjct: 1615 VWGTPDP 1621
Score = 36.3 bits (80), Expect = 0.13
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLR 258
+P I P G S F CRV P V W + + +K + D L
Sbjct: 6584 QPRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGLT 6643
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ V D+GEY+ A+NS G +L V
Sbjct: 6644 INRVKGDDKGEYTVRAKNSYGTKEEIVFLNV 6674
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 12/102 (11%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P P + T L W G S I+GYQV+ R+T SG W+
Sbjct: 5330 VPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQY--RDTSSGR--------WIN 5378
Query: 563 IARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+ Q H V L + F + +N+ G S PSP S+
Sbjct: 5379 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSE 5420
Score = 35.1 bits (77), Expect = 0.31
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 11/100 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P + + ++W +K G + I Y VEV +T + W +
Sbjct: 1992 PGKPGRPEITDFDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDT----------KEWKEV 2041
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+RV T+ + L G Y F VR N G PS S+
Sbjct: 2042 -KRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSE 2080
Score = 35.1 bits (77), Expect = 0.31
Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 33/186 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P+ W + R +VTN T + + + D+G Y + + HGK
Sbjct: 3885 PAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYKIIVENEHGK------ 3938
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQV 540
N+ V +PG P P+ + TL+W G + +L Y V
Sbjct: 3939 ----DTAQCNV------TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIV 3988
Query: 541 EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
E SRG W + T V K L+PG Y F V+ N G S P
Sbjct: 3989 EKMD-----------TSRGTWQEVGTFPDCTAKVNK-LVPGKEYAFRVKAVNLQGESKPL 4036
Query: 600 PVSDSV 605
+ +
Sbjct: 4037 EAEEPI 4042
Score = 35.1 bits (77), Expect = 0.31
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P ++ ++TL W++ G + I GY +E RE S W
Sbjct: 5032 PGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIE--KREV--------GSTEWTKA 5081
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
A + T + V L P TY F V N+ G
Sbjct: 5082 AFGNILDTKHRVTGLTPKKTYEFRVAAYNAAG 5113
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/94 (27%), Positives = 32/94 (34%), Gaps = 5/94 (5%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TL 452
P I P N T+ A+ C +P P W+ +I R DG L
Sbjct: 980 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVAL 1039
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
L D G YT + HG LLV S
Sbjct: 1040 ALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTS 1073
Score = 34.7 bits (76), Expect = 0.40
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 1/74 (1%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++ V Q +LN G P+P I W G V SD + G + SD
Sbjct: 3278 EIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRA-LRSD 3336
Query: 80 AGVYWCEATNSYGT 93
G Y +A N GT
Sbjct: 3337 TGTYIIKAENENGT 3350
Score = 34.7 bits (76), Expect = 0.40
Identities = 35/152 (23%), Positives = 61/152 (40%), Gaps = 15/152 (9%)
Query: 178 YQCIARNAAGTRESAIAT-----LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
++ IA NAAG + + T ++KP ++T + + G + + G P P
Sbjct: 4121 FRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPDPT 4180
Query: 233 VLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
W + G L ++D S+ + AD G Y + +N +G A +
Sbjct: 4181 ATW--TVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGEDEAIFEVI 4238
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D PS P +E +V + +C +P
Sbjct: 4239 VQDRPSAPEGP----LEVSDVTKDSCVLNWKP 4266
Score = 33.9 bits (74), Expect = 0.71
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 3/82 (3%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LV 453
PPI+ +QT I V C II WY +G + + + + +G+ L
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 454 LKDLDKSDSGTYTCVASSRHGK 475
+ L + SG Y C A +G+
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGE 458
Score = 33.5 bits (73), Expect = 0.93
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 13/114 (11%)
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNVESGNVAR 311
+L ++N + D G+Y+CEA V LTV +PP +N PN+ + A
Sbjct: 1185 TLIINNPEVDDTGKYTCEA----NGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAV 1240
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
TC P + W G++ I G R AV G LTI + +++D
Sbjct: 1241 LTC-KVNTPRAPLVW-YRGSKA-IQEGDPRFIIEKDAV--GRCTLTIKEVEEDD 1289
Score = 32.7 bits (71), Expect = 1.6
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 12/100 (12%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P PP P+ T NVT + L W + + + Y +E+ +E SGN
Sbjct: 1591 VKDKPKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEM--QEGRSGN------- 1641
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
W + T + VK L Y F V+ N GLS P
Sbjct: 1642 -WAKVGE-TKGTDFKVKDLKEHGEYKFRVKALNECGLSDP 1679
Score = 32.3 bits (70), Expect = 2.2
Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 1/83 (1%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV + GG P P ++W+KG + + +I + + SD
Sbjct: 2101 ITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDV 2160
Query: 81 GVYWCEATNSYGTARSRNATLHV 103
G Y NS+G A A L V
Sbjct: 2161 GEYRLTVKNSHG-ADEEKANLTV 2182
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 11/101 (10%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P KP + + + W+ G + + GY VE + S W
Sbjct: 4050 VPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVE----------KKEKGSAIWTE 4099
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
A + T + +L PG+ Y F V N+ G S PS +D
Sbjct: 4100 -AGKTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTD 4139
Score = 32.3 bits (70), Expect = 2.2
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
+ D P P +E+ + + L W PP+ +G N VV D N + V ++
Sbjct: 4239 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPK---DDGGAEISNYVVEKRDTKTN-TWVPVS 4294
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
V TS+ + LT G Y ++ AE G
Sbjct: 4295 AFV-TGTSITVPKLTEGHEYEFRVMAENTFG 4324
Score = 31.9 bits (69), Expect = 2.9
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 12/94 (12%)
Query: 504 PGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
P P P+ +V + ++ LSW + G I Y+VE +T +G WV
Sbjct: 2186 PSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVE--KLDTATGR--------WVP 2235
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
A +V T + L G TY F V+ N G S
Sbjct: 2236 CA-KVKDTKAHIDGLKKGQTYQFRVKAVNKEGAS 2268
Score = 31.1 bits (67), Expect = 5.0
Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 11/111 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PGPP ++ T++W + G S I GY VE+ RE S W V
Sbjct: 5431 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEI--RE--------YGSTLWTVA 5480
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ V + + V L Y F V N+ G PS S + + + S
Sbjct: 5481 SDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5531
Score = 30.3 bits (65), Expect = 8.7
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 11/123 (8%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD---DGSLRLD 260
+ G D+ + G+ + G+P P W+ A + G R V + ++ +
Sbjct: 3861 LAGLLDLRIKAGTPIKLDIAFEGEPAPVAKWK--ANDATIDTGARADVTNTPTSSAIHIF 3918
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ + D G Y EN G +A +TV D P P ++ + + CT +P
Sbjct: 3919 SAVRGDTGVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKID----EIHKEGCTLNWKP 3974
Query: 321 EPT 323
PT
Sbjct: 3975 -PT 3976
>Z73899-10|CAA98081.2| 6839|Caenorhabditis elegans Hypothetical
protein ZK617.1a protein.
Length = 6839
Score = 76.6 bits (180), Expect = 1e-13
Identities = 86/324 (26%), Positives = 130/324 (40%), Gaps = 44/324 (13%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + +N E G F C +G P P W +G + ++ KY T + G
Sbjct: 5604 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRW-FKGCKELV----DTSKY--TLINKG 5656
Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLP 410
VL IND +D+ + C A N +G+ R L + T PP G Q
Sbjct: 5657 DKQVLIINDLTSDDA-DEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGE 5715
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTC 467
+ + P A P+ W +GE + N + ++T D TL + + + D G Y
Sbjct: 5716 TIELKI-PYKAY--PQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRV 5772
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
V + G SG + V V+ +P PP PI N+ D +V LSW
Sbjct: 5773 VVENSVGSD--SGTVNVT--------------VADVPEPPRFPIIENILDEAVILSWKPP 5816
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
G S + Y +E RE + G+ +P + T+ ++ L G Y F +
Sbjct: 5817 ALDGGSLVTNYTIE--KREAMGGSWSP---------CAKSRYTYTTIEGLRAGKQYEFRI 5865
Query: 588 RTENSHGLSGP-SPVSDSVTVGDD 610
EN HG S P P + + GD+
Sbjct: 5866 IAENKHGQSKPCEPTAPVLIPGDE 5889
Score = 73.7 bits (173), Expect = 7e-13
Identities = 52/192 (27%), Positives = 88/192 (45%), Gaps = 12/192 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SGE P I+ D+ + T C GSP P RW+KG +V + +++ G
Sbjct: 5600 SGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQ 5659
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDT 124
L + DA Y C ATNS GT RS A L + F + P+ ++ +G+T
Sbjct: 5660 VL-IINDLTSDDADEYTCRATNSSGT-RSTRANLRIKTKPRVF-IPPKYHGGYEAQKGET 5716
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCI 181
+ L+ +P + P+ W K+G+ + + +S+ + L I +A + D G Y+ +
Sbjct: 5717 IELK-IPYKAYPQGEARWTKDGEKI--ENNSKFSITTDDKFATLRISNASREDYGEYRVV 5773
Query: 182 ARNAAGTRESAI 193
N+ G+ +
Sbjct: 5774 VENSVGSDSGTV 5785
Score = 72.9 bits (171), Expect = 1e-12
Identities = 121/493 (24%), Positives = 190/493 (38%), Gaps = 72/493 (14%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G P P+V W NG+ + G+S+ + + + A + +G+Y A N GT +
Sbjct: 2386 GEPAPDVTWSFNGKGI---GESKAQIENEPYISRFALPKALRKQSGKYTITATNINGT-D 2441
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGGNM 244
S +K+ KP GP +V T + GG+P+ ++ + G +
Sbjct: 2442 SVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWV 2501
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT------VYDPPSINLS 298
P GR D +D++ D ++ +A NS G T +D P
Sbjct: 2502 PCGRS---GDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGR 2558
Query: 299 PNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH----ATAVFDGV 353
P + +S +V ++ + P + +E R KY A V G
Sbjct: 2559 PEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIE----------KRTKYGRWEPAITVPGGQ 2608
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPI 411
T T+ D N+ V AVN G S K + + P I + N T+
Sbjct: 2609 TTATVPDLTPNEEYEFRVV-AVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKA 2667
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTC 467
F P P + W++ I+N R N LV+K +++ DSGT+T
Sbjct: 2668 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTI 2727
Query: 468 VASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
A + +G+ + + ++D P +PN DVS + G VTL+W
Sbjct: 2728 KAVNANGEDEATVKINVIDKPTSPN----GPLDVSDVHG------------DHVTLNWRA 2771
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV-HQTHYVVKSLIPGITYMF 585
+ G I Y +E + +T SG WV A+ +T VV LIPG Y F
Sbjct: 2772 PDDDGGIPIENYVIEKY--DTASGR--------WVPAAKVAGDKTTAVVDGLIPGHEYKF 2821
Query: 586 IVRTENSHGLSGP 598
V N+ G S P
Sbjct: 2822 RVAAVNAEGESDP 2834
Score = 72.1 bits (169), Expect = 2e-12
Identities = 118/494 (23%), Positives = 170/494 (34%), Gaps = 39/494 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I +P V Q A CR S P + W+K + G + L
Sbjct: 6266 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGL-- 6323
Query: 72 THGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLEC 129
T RV D G Y A NSYGT + L+V E + EP E + A V E
Sbjct: 6324 TINRVKGDDKGEYTVRAKNSYGT-KEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVEEF 6382
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ---DARQTDAGRYQCIARNAA 186
R +P + + L N I+ D D R Q R+
Sbjct: 6383 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGV 6442
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+ E A + Y +T D+ V GG+P+P V R P
Sbjct: 6443 CSLEIFNARVD-DAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRVSSFR-------PR 6494
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVN 303
L G+ + AD S + S SA+ L + PS +
Sbjct: 6495 RAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSFTAQLSDSE 6554
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
E G A F+ +G+PEP + W G R S ++ A+ V G L I+D K
Sbjct: 6555 TEVGGSAEFSAAVSGQPEPLIEWLHNGERI----SESDSRFRASYV-AGKATLRISDAKK 6609
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD----------RPPPIITNGPSNQTLPIKS 413
+D +C A N AG R LTV D +T + +
Sbjct: 6610 SD-EGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGE 6668
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
F TPE ++ W G+ L + +++ DG + + D SD+G Y
Sbjct: 6669 SVTFEARVQGTPEEVL-WMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVR 6727
Query: 471 SRHGKYVWSGALLV 484
S+ V +L+V
Sbjct: 6728 SKGTNLVSVASLVV 6741
Score = 68.1 bits (159), Expect = 4e-11
Identities = 57/180 (31%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178
G V EC GSP P W K + L+ S+ L++ G+ L+I D DA Y
Sbjct: 5618 GRCVTFEC-EISGSPRPEYRWFKGCKELV--DTSKYTLINKGDKQVLIINDLTSDDADEY 5674
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLW 235
C A N++GTR S A L+I KP + P+ AQ G ++ + P + W
Sbjct: 5675 TCRATNSSGTR-STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARW 5733
Query: 236 RRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ DD +LR+ N D GEY ENSVG+ S + +TV D P
Sbjct: 5734 TKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVP 5793
Score = 67.3 bits (157), Expect = 6e-11
Identities = 63/206 (30%), Positives = 93/206 (45%), Gaps = 32/206 (15%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G PEP + W NG+ + + DSR ++ L I DA+++D G+Y C A N+AG +E
Sbjct: 6569 GQPEPLIEWLHNGERIS-ESDSRFRASYVAGKATLRISDAKKSDEGQYLCRASNSAG-QE 6626
Query: 191 SAIATLKIHIKPYLITGPE---------------DVVAQTGSSVTFQCRVGGDPLPDVLW 235
ATL + L+ G + G SVTF+ RV G P +VLW
Sbjct: 6627 QTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGESVTFEARVQGTP-EEVLW 6685
Query: 236 RRSAGGGNMPLG-RVKVLDDG---SLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTV- 289
R+ G + G + + DG S +++ +D G Y E + VS + + V
Sbjct: 6686 MRN--GQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVRSKGTNLVSVASLVVVG 6743
Query: 290 --YDPPSINLSPNSVNVESGNVARFT 313
DPP L P+SV+ G FT
Sbjct: 6744 EKADPPVTRL-PSSVSAPLGGSTAFT 6768
Score = 66.1 bits (154), Expect = 1e-10
Identities = 123/504 (24%), Positives = 191/504 (37%), Gaps = 63/504 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186
+P G P P V W + +G R+ L + LV++ + D+G + A NA
Sbjct: 2675 VPVSGEPAPTVTWHWPDNREIRNG-GRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNAN 2733
Query: 187 GTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRR--S 238
G E AT+KI++ KP GP DV G VT R GG P+ + + + +
Sbjct: 2734 GEDE---ATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDT 2790
Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDP--- 292
A G +P +V D + +D +I E ++ A N+ G + G DP
Sbjct: 2791 ASGRWVPAAKVAG-DKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDK 2849
Query: 293 PSINLSPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P +P + + +V + A P + VE F D H A
Sbjct: 2850 PGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDE--FSPFWNDVAHVPAGQT 2907
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
TV + + K + R A N AG + + PP+I S Q + +
Sbjct: 2908 NATVGNLKEGSKYEFR----IRAKNKAGLGDPSDSASAVAKARNVPPVIDRN-SIQEIKV 2962
Query: 412 KSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRNVTN-DG--TLVLKDLDKSDSGTYT 466
K+ F + P P I W FEG + + R + N DG +K +SD+GTY
Sbjct: 2963 KAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 3022
Query: 467 CVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
A + +G + V D P +P GP +T N+ L+W
Sbjct: 3023 IKAENENGTDTAEVKVTVLDHPSSPR-------------GP--LDVT-NIVKDGCDLAWK 3066
Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585
+ G + I Y +E ++ +G W T++ V L G Y F
Sbjct: 3067 EPEDDGGAEISHYVIE--KQDAATGR--------WTACGES-KDTNFHVDDLTQGHEYKF 3115
Query: 586 IVRTENSHGLSGPSPVSDSVTVGD 609
V+ N HG S P +++ D
Sbjct: 3116 RVKAVNRHGDSDPLEAREAIIAKD 3139
Score = 64.1 bits (149), Expect = 6e-10
Identities = 80/312 (25%), Positives = 116/312 (37%), Gaps = 45/312 (14%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + P A FTC A GRPEPT W G P SR ++ A+ DG
Sbjct: 5214 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRE---LPESSRYRFEAS---DG 5267
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
V TI + D+ V N GS L V + PP+I N LP
Sbjct: 5268 VYKFTIKEVWDIDAGEYTV-EVSNPYGSDTATANLVVQA-----PPVIEKDVPNTILPSG 5321
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEA-----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
+ YF G A L+ N + T+ + + D T
Sbjct: 5322 DLVRLKI------------YFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPA 5369
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQ 526
++ G+Y ++ + + F+ +V+ LP P P+ N+ ++ TLSW
Sbjct: 5370 LSVREAGRYEYT---VSNDSGEATTGFW--LNVTGLPEAPQGPLHISNIGPSTATLSWRP 5424
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
G S I Y VE + LS + WV + V +Y+V L Y F
Sbjct: 5425 PVTDGGSKITSYVVE---KRDLSKDE-------WVTVTSNVKDMNYIVTGLFENHEYEFR 5474
Query: 587 VRTENSHGLSGP 598
V +N +G+ P
Sbjct: 5475 VSAQNENGIGAP 5486
Score = 60.9 bits (141), Expect = 5e-09
Identities = 84/305 (27%), Positives = 118/305 (38%), Gaps = 30/305 (9%)
Query: 2 SDDYVT--SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHR 58
+DD T + E P Q D A + G P P I W G + SD+
Sbjct: 6532 ADDLKTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRF 6591
Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV------------AVL 106
G LR + + SD G Y C A+NS G ++R ATL V +
Sbjct: 6592 RASYVAGKATLRISDAK-KSDEGQYLCRASNSAGQEQTR-ATLTVKGDQPLLNGHAGQAV 6649
Query: 107 REEFRLEPE--SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
E R+ + G++V E +G+PE V W +NGQ L +GD DG
Sbjct: 6650 ESELRVTKHLGGEIVNNGESVTFEA-RVQGTPE-EVLWMRNGQELT-NGDKTSISQDGET 6706
Query: 165 L--VIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGSSV 219
L I A +DAG YQ R + GT ++A+L + P + P V A G S
Sbjct: 6707 LSFTINSADASDAGHYQLEVR-SKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGST 6765
Query: 220 TFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
F V W R + N + VK + L + NV D+G Y +
Sbjct: 6766 AFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKE 6825
Query: 278 VGAVS 282
A++
Sbjct: 6826 KKAIA 6830
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SG AP I+E P +VTV ++ A L C+ GSP+P RW+KG V+S + G
Sbjct: 657 SGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEH 716
Query: 68 FLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
+ + S D G Y N +GT + L + +FR + ++S G
Sbjct: 717 TVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTSDNGLDFRAMLKHRESQAG 772
Score = 56.0 bits (129), Expect = 2e-07
Identities = 83/317 (26%), Positives = 122/317 (38%), Gaps = 41/317 (12%)
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
++L V++G T T P+P + W+ EG + + D T
Sbjct: 4130 LDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLA----------GVETTDSQT 4179
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
L I T ++DS + AVN G + K+TV D+P P N T P S
Sbjct: 4180 KLVIPSTRRSDS-GPVKIKAVNPYGEAEANIKITVI---DKP-----GAPENITYPAVSR 4230
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
CT A +G A I ++ G+ + + SGT V HG
Sbjct: 4231 HT--CTLNWD-----APKDDGGAEIAGYKIEYQEVGSQIWDKVPGLISGTAYTVRGLEHG 4283
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVT--DTS-VTLSWSQNNKI 530
+ + + ++ + + + V P PP P T +T DT+ V+L+W+
Sbjct: 4284 QQ-YRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQVSLAWNPPRDD 4342
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
G S ILGY VE F + R W + V T +V L TY F VR
Sbjct: 4343 GGSPILGYVVERFEK---------RGGGDWAPVKMPMVKGTECIVPGLHENETYQFRVRA 4393
Query: 590 ENSHGLSGPSPVSDSVT 606
N+ G PS S+ VT
Sbjct: 4394 VNAAGHGEPSNGSEPVT 4410
Score = 54.0 bits (124), Expect = 6e-07
Identities = 114/486 (23%), Positives = 176/486 (36%), Gaps = 52/486 (10%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+P G P P + W G + D +++ DG ++ A ++D G Y A N GT
Sbjct: 2972 IPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENGT 3031
Query: 189 RESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGN 243
++A + + P GP DV + + G + ++ GG + V+ ++ A G
Sbjct: 3032 -DTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISHYVIEKQDAATGR 3090
Query: 244 MPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSP 299
G K D + +D++ E ++ +A N G + A + DP P
Sbjct: 3091 WTACGESK---DTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEAREAIIAKDPFDRADKP 3147
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ + + T P +EG + S D A V G T++
Sbjct: 3148 GTPEIVDWDKDHADLKWTP-PADDGGAPIEGY-LVEMRTPSGDWVPAVTVGAGELTATVD 3205
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+ V A+N AG S + V P I + Q + F
Sbjct: 3206 GLKPGQTYQFRV-KALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNF 3264
Query: 418 PCTAICTPEPIIAWYFEGEALIQN---HRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRH 473
P P I W+ G L H N T++ T L K ++DSG Y VA++
Sbjct: 3265 DVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNES 3324
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGS 532
GK + ++ NI +PG P P+ H ++T SV L W + G
Sbjct: 3325 GK--------DEHEVDVNI--------LDIPGAPEGPLRHKDITKESVVLKWDEPLDDGG 3368
Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
S I Y VE ++ G WV T V L G Y F V+ N
Sbjct: 3369 SPITNYVVE---KQEDGGR--------WVPCG-ETSDTSLKVNKLSEGHEYKFRVKAVNR 3416
Query: 593 HGLSGP 598
G S P
Sbjct: 3417 QGTSAP 3422
Score = 51.6 bits (118), Expect = 3e-06
Identities = 110/454 (24%), Positives = 173/454 (38%), Gaps = 65/454 (14%)
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI------KPYLITGPEDVVAQTGSSVT 220
+ R+ + ++ +A NAAG ++ + I I +P ++ PED
Sbjct: 5173 VDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAV 5232
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKV-LDDGSLR--LDNVILADEGEYSCEAEN 276
F C G P P W R+ G +P R + DG + + V D GEY+ E N
Sbjct: 5233 FTCEAVGRPEPTARWLRN--GRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSN 5290
Query: 277 SVGAVSASGYLTVYDPPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
G+ +A+ L V PP I PN++ + SG++ R +G + +++
Sbjct: 5291 PYGSDTATANLVVQAPPVIEKDVPNTI-LPSGDLVRLKIYFSG--------TAPFRHSLV 5341
Query: 336 FPGMSRDKYHAT---AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
D H T FD ++TI ++ + N +G + L VT
Sbjct: 5342 LNREEIDMDHPTIRIVEFDDHILITIPALSVREA-GRYEYTVSNDSGEATTGFWLNVTGL 5400
Query: 393 DDRP--PPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN- 448
+ P P I+N GPS TL + P T I ++ E L ++ VT+
Sbjct: 5401 PEAPQGPLHISNIGPSTATLSWRP----PVTD--GGSKITSYVVEKRDLSKDEWVTVTSN 5454
Query: 449 --DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPG 505
D ++ L ++ + A + +G GA LV + PI + F
Sbjct: 5455 VKDMNYIVTGLFENHEYEFRVSAQNENG----IGAPLVSEHPIIARLPF----------D 5500
Query: 506 PPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
PPT P+ + VTLSW + G + GY VE E +N
Sbjct: 5501 PPTSPLNLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPS---- 5556
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
+Y V +LI G Y + V N GLS
Sbjct: 5557 -----PPNNYNVPNLIDGRKYRYRVFAVNDAGLS 5585
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/209 (22%), Positives = 82/209 (39%), Gaps = 17/209 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P +++ D+ + G VTF+C + G P P+ W + + + +++ G L
Sbjct: 5604 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGC-KELVDTSKYTLINKGDKQVLI 5662
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCT 315
++++ D EY+C A NS G S L + P + + P + G
Sbjct: 5663 INDLTSDDADEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIP 5722
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
P+ W+ +G + + K+ T D L I++ + D V
Sbjct: 5723 YKAYPQGEARWTKDGEKI-----ENNSKFSIT-TDDKFATLRISNASREDYGEYRVV-VE 5775
Query: 376 NYAGSSFVRGKLTVTSDDDRPP--PIITN 402
N GS +TV +D PP PII N
Sbjct: 5776 NSVGSDSGTVNVTV-ADVPEPPRFPIIEN 5803
Score = 49.2 bits (112), Expect = 2e-05
Identities = 51/221 (23%), Positives = 81/221 (36%), Gaps = 10/221 (4%)
Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNL 165
R + ++PE V C G PEP W +NG+ L R DG
Sbjct: 5213 RPQIVVKPEDTAQPYNRRAVFTC-EAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKF 5271
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
I++ DAG Y N G+ ++A A L + P + + + +G V +
Sbjct: 5272 TIKEVWDIDAGEYTVEVSNPYGS-DTATANLVVQAPPVIEKDVPNTILPSGDLVRLKIYF 5330
Query: 226 GGD-PL-PDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVILADEGEYSCEAENSVGAVS 282
G P ++ R + P R+ DD L + + + + G Y N G +
Sbjct: 5331 SGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEAT 5390
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
+L V P P ++ N+ T T + RP T
Sbjct: 5391 TGFWLNVTGLPEAPQGPLHIS----NIGPSTATLSWRPPVT 5427
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 32/185 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVWSGA 481
P+PII + + +N R V N G +V+ +SD+G Y A++++GK
Sbjct: 4548 PKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCK-- 4605
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQV 540
++ F V PG PT PI ++ ++TLSW G +I Y V
Sbjct: 4606 ----------LNVF----VLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAITNYVV 4651
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E + T G+ WV + V T V++L Y F VR EN +G+ P
Sbjct: 4652 E---KRTPGGD--------WVTVGHPVGTT-LRVRNLDANTPYEFRVRAENQYGVGEPLE 4699
Query: 601 VSDSV 605
D++
Sbjct: 4700 TDDAI 4704
Score = 48.4 bits (110), Expect = 3e-05
Identities = 24/91 (26%), Positives = 51/91 (56%), Gaps = 4/91 (4%)
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVI 263
G +D+ + G ++ + + G+PLP+ LW + G +GRVK+ + ++++N +
Sbjct: 1482 GIKDLRLKVGETIKYDVPISGEPLPECLWVVN-GKPLKAVGRVKMSSERGKHIMKIENAV 1540
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
AD G+++ +NS G+ ++ +TV P+
Sbjct: 1541 RADSGKFTITLKNSSGSCDSTATVTVVGRPT 1571
Score = 47.6 bits (108), Expect = 5e-05
Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 12/181 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
G+T+ + +P G P P W NG+ L G +M G +++ I++A + D+G++
Sbjct: 1491 GETIKYD-VPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1549
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQ--CRVGGDPLPDVLWR 236
+N++G+ +S AT+ + +P GP D+ V G+++++ GGDPL +
Sbjct: 1550 TLKNSSGSCDST-ATVTVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVE 1608
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS--CEAENSVG---AVSASGYLTVYD 291
V +D + L L ++G Y +A N+ G +SA Y + D
Sbjct: 1609 AQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKD 1668
Query: 292 P 292
P
Sbjct: 1669 P 1669
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 7/100 (7%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVI 263
+ + + G++V ++ ++GG+P+P+V W + G + G +D L + + +
Sbjct: 1780 KSITVKAGATVRWEVKIGGEPIPEVKWFK--GNQQLENGIQLTIDTRKNEHTILCIPSAM 1837
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
+D GEY +NS GA LTV D PS P V+
Sbjct: 1838 RSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVS 1877
Score = 45.2 bits (102), Expect = 3e-04
Identities = 48/204 (23%), Positives = 78/204 (38%), Gaps = 23/204 (11%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNL--- 165
F +P +Q+ GD +++EC P+P + W+ +G L G L GG+L
Sbjct: 7 FTQKPSIQQTPTGD-LLMEC-HLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKA 64
Query: 166 --VIQDARQTDAGRYQCIARNAAGTRESAI--------ATLKIHIKPYLITGPEDVVAQT 215
VI++ D G Y+C ARN G + I P + P +
Sbjct: 65 TLVIKEPNAGDGGAYKCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKDG 124
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGS----LRLDNVILADEG 268
G+ + +C+V P W + G + L D + L + +D G
Sbjct: 125 GALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAG 184
Query: 269 EYSCEAENSVGAVSASGYLTVYDP 292
+Y C N G +A+ L +P
Sbjct: 185 QYRCNIRNDQGETNANLALNFEEP 208
Score = 43.6 bits (98), Expect = 9e-04
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 6/97 (6%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLV 453
P T S+ + A F PEP+I W GE + ++ R V TL
Sbjct: 6544 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6603
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPI 488
+ D KSD G Y C AS+ G+ L V D P+
Sbjct: 6604 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPL 6640
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/182 (24%), Positives = 70/182 (38%), Gaps = 20/182 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGLFFLRATHGRVHS--DAGVYWCE 86
+ C P P I W G L+ +++ P GG + + + D G Y C
Sbjct: 23 MECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKATLVIKEPNAGDGGAYKCT 82
Query: 87 ATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQGDTVVLECLPPRGSPEP 138
A N G + + N L+ A + F +P G +V+EC + + P
Sbjct: 83 ARNQLGESNA-NINLNFAGAGGDEAKSRGPSFVGKPRIIPKDGGALIVMEC-KVKSASTP 140
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGN------LVIQDARQTDAGRYQCIARNAAGTRESA 192
W K+G L G D G+ L I+ +DAG+Y+C RN G +
Sbjct: 141 VAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNAN 200
Query: 193 IA 194
+A
Sbjct: 201 LA 202
Score = 42.7 bits (96), Expect = 0.002
Identities = 117/488 (23%), Positives = 174/488 (35%), Gaps = 59/488 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188
+P RG P P W N + + D R+ D V++ A + AG Y A NA+G+
Sbjct: 2090 VPVRGEPPPKKEWIFNEKPV-DDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGS 2148
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGG 242
+ ++ + + KP GP +V + +V GG P+ ++ A G
Sbjct: 2149 DKHSVEVIVLG-KPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATGR 2207
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+P GR + + N+ E ++ A N G S LT + L+ N
Sbjct: 2208 WVPCGRSETT---KTTVPNLQPGHEYKFRVRAVNKEG---ESDPLTT---NTAILAKNPY 2258
Query: 303 NVESGNVARFTCTATGRPEPTMFWSV--EGNRTI-IFPGMSRDK---YHATAVFDGVTVL 356
V G V + + + W+ +G I F +DK + V G
Sbjct: 2259 EV-PGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQKT 2317
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
K SA N AG+ V + P I S+ T+ + +
Sbjct: 2318 ATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGAT 2377
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASS 471
F P P + W F G+ I + + N+ L + SG YT A++
Sbjct: 2378 LKFIVHIDGEPAPDVTWSFNGKG-IGESKAQIENEPYISRFALPKALRKQSGKYTITATN 2436
Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKI 530
+G DS + NI V S P P PI +V + TL W
Sbjct: 2437 ING---------TDS-VTINI------KVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDD 2480
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G I Y++E T G WV R TH+ V SL G Y F V+
Sbjct: 2481 GGEPIEFYEIE--KMNTKDGI--------WVPCGRS-GDTHFTVDSLNKGDHYKFRVKAV 2529
Query: 591 NSHGLSGP 598
NS G S P
Sbjct: 2530 NSEGPSDP 2537
Score = 42.7 bits (96), Expect = 0.002
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ G P I+ +P D ++ A C A G P P RW + G + + + G+
Sbjct: 5209 SGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGV 5268
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGT 93
+ + T V DAG Y E +N YG+
Sbjct: 5269 Y--KFTIKEVWDIDAGEYTVEVSNPYGS 5294
Score = 41.5 bits (93), Expect = 0.004
Identities = 45/153 (29%), Positives = 66/153 (43%), Gaps = 15/153 (9%)
Query: 178 YQCIARNAAGTRESAIATLKIHI-----KPYLITG--PEDVVAQTGSSVTFQCRVGGDPL 230
++ A NAAG E ++ ++ I +P + G D++A G P
Sbjct: 4785 FRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPA 4844
Query: 231 PDVLWRRSAGGGNMPLGRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P V + + + RVKV D +L ++ L D G Y E ENS G+ SAS L
Sbjct: 4845 PKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQGSDSASIRL 4904
Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D P+ SP + VE ++A CT P
Sbjct: 4905 KVVDKPA---SPQHIRVE--DIAPDCCTLYWMP 4932
Score = 40.3 bits (90), Expect = 0.008
Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 18/147 (12%)
Query: 178 YQCIARNAAGTRE----SAIATLK-IHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDP 229
Y+ +A N AG + SA AT K +H P + G E V + G + P
Sbjct: 4097 YRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRV-KAGEPLVITIPFTASP 4155
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
PD+ W + G PL V+ D + L + + +D G +A N G A+ +T
Sbjct: 4156 QPDISWTKEGG---KPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKIT 4212
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCT 315
V D P +P ++ + V+R TCT
Sbjct: 4213 VIDKPG---APENITYPA--VSRHTCT 4234
Score = 39.9 bits (89), Expect = 0.011
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P P +T S L+W++ + G + I GY VE ++ L N+ R +
Sbjct: 4418 PGAPDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVE---KKKLGDNDWTRCN------ 4468
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
+ V T + VK+L Y F V NS G PS SD V +
Sbjct: 4469 DKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLI 4512
Score = 39.5 bits (88), Expect = 0.014
Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 6/127 (4%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCR-AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G + I D+TV + + AGG+P P I + G + + R+++
Sbjct: 4517 GRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIF-ENERTVVDVNPGE 4575
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESKQSAQGDTVV 126
+ T G SDAG Y ATN YG L+V VL + P Q D +
Sbjct: 4576 IVITTTGSKRSDAGPYKISATNKYG---KDTCKLNVFVLDAPGKPTGPIRATDIQADAMT 4632
Query: 127 LECLPPR 133
L PP+
Sbjct: 4633 LSWRPPK 4639
Score = 38.7 bits (86), Expect = 0.025
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 8/102 (7%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P P ++ TL W + G S I Y VE G W +
Sbjct: 4910 PASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGK--------WEKV 4961
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
+ V +Y V LI Y F VR E +G+S P ++D V
Sbjct: 4962 SSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVV 5003
Score = 38.7 bits (86), Expect = 0.025
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
+++ AP+ + + ++ L C G+P+P I W K G V D +
Sbjct: 6380 EEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDED-RVQVSF 6438
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G+ L + RV DAG Y ATN G
Sbjct: 6439 RSGVCSLEIFNARV-DDAGTYTVTATNDLG 6467
Score = 37.9 bits (84), Expect = 0.043
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 9/86 (10%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR--RNVTNDG----- 450
P T PS Q P + + C P+P IAW G L + R + +T G
Sbjct: 5 PRFTQKPSIQQTPTGDL-LMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYK 63
Query: 451 -TLVLKDLDKSDSGTYTCVASSRHGK 475
TLV+K+ + D G Y C A ++ G+
Sbjct: 64 ATLVIKEPNAGDGGAYKCTARNQLGE 89
Score = 37.5 bits (83), Expect = 0.057
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I P +V V A TC +G P PT W +G+R +I G R K+
Sbjct: 661 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRW-FKGSREVISGG--RFKHITDGKEHT 717
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
V + + +++ T+ V+ S+ V KL VTSD+
Sbjct: 718 VALALLKCRSQDEGPYTLTIENVHGTDSADV--KLLVTSDN 756
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 11/111 (9%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P P P+ +VT S L+W G + I Y VE R+T + NT
Sbjct: 3920 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVVE--KRDTKT--NT----- 3970
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
WV ++ V T V L G Y F V EN+ G S + V D
Sbjct: 3971 -WVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKD 4020
Score = 36.7 bits (81), Expect = 0.10
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-----S 256
P ++ PE+V + C+V G P P W + + + GR K + DG +
Sbjct: 661 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGS-REVISGGRFKHITDGKEHTVA 719
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L L DEG Y+ EN G SA L V
Sbjct: 720 LALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 752
Score = 36.3 bits (80), Expect = 0.13
Identities = 72/307 (23%), Positives = 115/307 (37%), Gaps = 29/307 (9%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
ATL + + W+ G + + + + L R+ D G Y C
Sbjct: 1012 ATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIE-DHGEYKCT-- 1068
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T R + + +F + + + + D V L C + + P + W +NG+
Sbjct: 1069 ----TKDDRTMAQLIVDAKNKFIVALKDTEVIEKDDVTLMC-QTKDTKTPGI-WFRNGKQ 1122
Query: 149 L--LFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYL 204
+ + G +G + L I +A Y+ + AG R S + L+ +P L
Sbjct: 1123 ISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEI---DQAGLRGSCNVTVLEAEKRPIL 1179
Query: 205 ITGPEDVVAQTGS----SVTFQCRVG--GDPLPDVLWRRSAGGGNM-PLGRVKVLDD-GS 256
P+ + A+ G V FQ + GDP +L M L V + DD
Sbjct: 1180 NWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVIIKDDVAE 1239
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV-ARFTCT 315
+ N LAD G+++ E NS G A L V D P P +E+ NV A
Sbjct: 1240 IVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKP----KPPKGPLETKNVTAEGLDL 1295
Query: 316 ATGRPEP 322
G P+P
Sbjct: 1296 VWGTPDP 1302
Score = 36.3 bits (80), Expect = 0.13
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLR 258
+P I P G S F CRV P V W + + +K + D L
Sbjct: 6265 QPRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGLT 6324
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ V D+GEY+ A+NS G +L V
Sbjct: 6325 INRVKGDDKGEYTVRAKNSYGTKEEIVFLNV 6355
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 12/102 (11%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P P + T L W G S I+GYQV+ R+T SG W+
Sbjct: 5011 VPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQY--RDTSSGR--------WIN 5059
Query: 563 IARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+ Q H V L + F + +N+ G S PSP S+
Sbjct: 5060 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSE 5101
Score = 35.1 bits (77), Expect = 0.31
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 11/100 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P + + ++W +K G + I Y VEV +T + W +
Sbjct: 1673 PGKPGRPEITDFDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDT----------KEWKEV 1722
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+RV T+ + L G Y F VR N G PS S+
Sbjct: 1723 -KRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSE 1761
Score = 35.1 bits (77), Expect = 0.31
Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 33/186 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P+ W + R +VTN T + + + D+G Y + + HGK
Sbjct: 3566 PAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYKIIVENEHGK------ 3619
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQV 540
N+ V +PG P P+ + TL+W G + +L Y V
Sbjct: 3620 ----DTAQCNV------TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIV 3669
Query: 541 EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
E SRG W + T V K L+PG Y F V+ N G S P
Sbjct: 3670 EKMD-----------TSRGTWQEVGTFPDCTAKVNK-LVPGKEYAFRVKAVNLQGESKPL 3717
Query: 600 PVSDSV 605
+ +
Sbjct: 3718 EAEEPI 3723
Score = 35.1 bits (77), Expect = 0.31
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P ++ ++TL W++ G + I GY +E RE S W
Sbjct: 4713 PGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIE--KREV--------GSTEWTKA 4762
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
A + T + V L P TY F V N+ G
Sbjct: 4763 AFGNILDTKHRVTGLTPKKTYEFRVAAYNAAG 4794
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/94 (27%), Positives = 32/94 (34%), Gaps = 5/94 (5%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TL 452
P I P N T+ A+ C +P P W+ +I R DG L
Sbjct: 661 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVAL 720
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
L D G YT + HG LLV S
Sbjct: 721 ALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTS 754
Score = 34.7 bits (76), Expect = 0.40
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 1/74 (1%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++ V Q +LN G P+P I W G V SD + G + SD
Sbjct: 2959 EIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRA-LRSD 3017
Query: 80 AGVYWCEATNSYGT 93
G Y +A N GT
Sbjct: 3018 TGTYIIKAENENGT 3031
Score = 34.7 bits (76), Expect = 0.40
Identities = 35/152 (23%), Positives = 61/152 (40%), Gaps = 15/152 (9%)
Query: 178 YQCIARNAAGTRESAIAT-----LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
++ IA NAAG + + T ++KP ++T + + G + + G P P
Sbjct: 3802 FRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPDPT 3861
Query: 233 VLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
W + G L ++D S+ + AD G Y + +N +G A +
Sbjct: 3862 ATW--TVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGEDEAIFEVI 3919
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D PS P +E +V + +C +P
Sbjct: 3920 VQDRPSAPEGP----LEVSDVTKDSCVLNWKP 3947
Score = 33.9 bits (74), Expect = 0.71
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 3/82 (3%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LV 453
PPI+ +QT I V C II WY +G + + + + +G+ L
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 454 LKDLDKSDSGTYTCVASSRHGK 475
+ L + SG Y C A +G+
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGE 458
Score = 33.5 bits (73), Expect = 0.93
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 13/114 (11%)
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNVESGNVAR 311
+L ++N + D G+Y+CEA V LTV +PP +N PN+ + A
Sbjct: 866 TLIINNPEVDDTGKYTCEA----NGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAV 921
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
TC P + W G++ I G R AV G LTI + +++D
Sbjct: 922 LTC-KVNTPRAPLVW-YRGSKA-IQEGDPRFIIEKDAV--GRCTLTIKEVEEDD 970
Score = 32.7 bits (71), Expect = 1.6
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 12/100 (12%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P PP P+ T NVT + L W + + + Y +E+ +E SGN
Sbjct: 1272 VKDKPKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEM--QEGRSGN------- 1322
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
W + T + VK L Y F V+ N GLS P
Sbjct: 1323 -WAKVGE-TKGTDFKVKDLKEHGEYKFRVKALNECGLSDP 1360
Score = 32.3 bits (70), Expect = 2.2
Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 1/83 (1%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV + GG P P ++W+KG + + +I + + SD
Sbjct: 1782 ITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDV 1841
Query: 81 GVYWCEATNSYGTARSRNATLHV 103
G Y NS+G A A L V
Sbjct: 1842 GEYRLTVKNSHG-ADEEKANLTV 1863
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 11/101 (10%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P KP + + + W+ G + + GY VE + S W
Sbjct: 3731 VPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVE----------KKEKGSAIWTE 3780
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
A + T + +L PG+ Y F V N+ G S PS +D
Sbjct: 3781 -AGKTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTD 3820
Score = 32.3 bits (70), Expect = 2.2
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
+ D P P +E+ + + L W PP+ +G N VV D N + V ++
Sbjct: 3920 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPK---DDGGAEISNYVVEKRDTKTN-TWVPVS 3975
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
V TS+ + LT G Y ++ AE G
Sbjct: 3976 AFV-TGTSITVPKLTEGHEYEFRVMAENTFG 4005
Score = 31.9 bits (69), Expect = 2.9
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 12/94 (12%)
Query: 504 PGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
P P P+ +V + ++ LSW + G I Y+VE +T +G WV
Sbjct: 1867 PSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVE--KLDTATGR--------WVP 1916
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
A +V T + L G TY F V+ N G S
Sbjct: 1917 CA-KVKDTKAHIDGLKKGQTYQFRVKAVNKEGAS 1949
Score = 31.1 bits (67), Expect = 5.0
Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 11/111 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PGPP ++ T++W + G S I GY VE+ RE S W V
Sbjct: 5112 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEI--RE--------YGSTLWTVA 5161
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ V + + V L Y F V N+ G PS S + + + S
Sbjct: 5162 SDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5212
Score = 30.3 bits (65), Expect = 8.7
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 11/123 (8%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD---DGSLRLD 260
+ G D+ + G+ + G+P P W+ A + G R V + ++ +
Sbjct: 3542 LAGLLDLRIKAGTPIKLDIAFEGEPAPVAKWK--ANDATIDTGARADVTNTPTSSAIHIF 3599
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ + D G Y EN G +A +TV D P P ++ + + CT +P
Sbjct: 3600 SAVRGDTGVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKID----EIHKEGCTLNWKP 3655
Query: 321 EPT 323
PT
Sbjct: 3656 -PT 3657
>Z73897-6|CAM35838.1| 6629|Caenorhabditis elegans Hypothetical protein
ZK617.1c protein.
Length = 6629
Score = 76.6 bits (180), Expect = 1e-13
Identities = 86/324 (26%), Positives = 130/324 (40%), Gaps = 44/324 (13%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + +N E G F C +G P P W +G + ++ KY T + G
Sbjct: 5394 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRW-FKGCKELV----DTSKY--TLINKG 5446
Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLP 410
VL IND +D+ + C A N +G+ R L + T PP G Q
Sbjct: 5447 DKQVLIINDLTSDDA-DEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGE 5505
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTC 467
+ + P A P+ W +GE + N + ++T D TL + + + D G Y
Sbjct: 5506 TIELKI-PYKAY--PQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRV 5562
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
V + G SG + V V+ +P PP PI N+ D +V LSW
Sbjct: 5563 VVENSVGSD--SGTVNVT--------------VADVPEPPRFPIIENILDEAVILSWKPP 5606
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
G S + Y +E RE + G+ +P + T+ ++ L G Y F +
Sbjct: 5607 ALDGGSLVTNYTIE--KREAMGGSWSP---------CAKSRYTYTTIEGLRAGKQYEFRI 5655
Query: 588 RTENSHGLSGP-SPVSDSVTVGDD 610
EN HG S P P + + GD+
Sbjct: 5656 IAENKHGQSKPCEPTAPVLIPGDE 5679
Score = 73.7 bits (173), Expect = 7e-13
Identities = 52/192 (27%), Positives = 88/192 (45%), Gaps = 12/192 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SGE P I+ D+ + T C GSP P RW+KG +V + +++ G
Sbjct: 5390 SGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQ 5449
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDT 124
L + DA Y C ATNS GT RS A L + F + P+ ++ +G+T
Sbjct: 5450 VL-IINDLTSDDADEYTCRATNSSGT-RSTRANLRIKTKPRVF-IPPKYHGGYEAQKGET 5506
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCI 181
+ L+ +P + P+ W K+G+ + + +S+ + L I +A + D G Y+ +
Sbjct: 5507 IELK-IPYKAYPQGEARWTKDGEKI--ENNSKFSITTDDKFATLRISNASREDYGEYRVV 5563
Query: 182 ARNAAGTRESAI 193
N+ G+ +
Sbjct: 5564 VENSVGSDSGTV 5575
Score = 72.9 bits (171), Expect = 1e-12
Identities = 121/493 (24%), Positives = 190/493 (38%), Gaps = 72/493 (14%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G P P+V W NG+ + G+S+ + + + A + +G+Y A N GT +
Sbjct: 2176 GEPAPDVTWSFNGKGI---GESKAQIENEPYISRFALPKALRKQSGKYTITATNINGT-D 2231
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGGNM 244
S +K+ KP GP +V T + GG+P+ ++ + G +
Sbjct: 2232 SVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWV 2291
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT------VYDPPSINLS 298
P GR D +D++ D ++ +A NS G T +D P
Sbjct: 2292 PCGRS---GDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGR 2348
Query: 299 PNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH----ATAVFDGV 353
P + +S +V ++ + P + +E R KY A V G
Sbjct: 2349 PEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIE----------KRTKYGRWEPAITVPGGQ 2398
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPI 411
T T+ D N+ V AVN G S K + + P I + N T+
Sbjct: 2399 TTATVPDLTPNEEYEFRVV-AVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKA 2457
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTC 467
F P P + W++ I+N R N LV+K +++ DSGT+T
Sbjct: 2458 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTI 2517
Query: 468 VASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
A + +G+ + + ++D P +PN DVS + G VTL+W
Sbjct: 2518 KAVNANGEDEATVKINVIDKPTSPN----GPLDVSDVHG------------DHVTLNWRA 2561
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV-HQTHYVVKSLIPGITYMF 585
+ G I Y +E + +T SG WV A+ +T VV LIPG Y F
Sbjct: 2562 PDDDGGIPIENYVIEKY--DTASGR--------WVPAAKVAGDKTTAVVDGLIPGHEYKF 2611
Query: 586 IVRTENSHGLSGP 598
V N+ G S P
Sbjct: 2612 RVAAVNAEGESDP 2624
Score = 72.1 bits (169), Expect = 2e-12
Identities = 118/494 (23%), Positives = 170/494 (34%), Gaps = 39/494 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I +P V Q A CR S P + W+K + G + L
Sbjct: 6056 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGL-- 6113
Query: 72 THGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLEC 129
T RV D G Y A NSYGT + L+V E + EP E + A V E
Sbjct: 6114 TINRVKGDDKGEYTVRAKNSYGT-KEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVEEF 6172
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ---DARQTDAGRYQCIARNAA 186
R +P + + L N I+ D D R Q R+
Sbjct: 6173 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGV 6232
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+ E A + Y +T D+ V GG+P+P V R P
Sbjct: 6233 CSLEIFNARVD-DAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRVSSFR-------PR 6284
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVN 303
L G+ + AD S + S SA+ L + PS +
Sbjct: 6285 RAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSFTAQLSDSE 6344
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
E G A F+ +G+PEP + W G R S ++ A+ V G L I+D K
Sbjct: 6345 TEVGGSAEFSAAVSGQPEPLIEWLHNGERI----SESDSRFRASYV-AGKATLRISDAKK 6399
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD----------RPPPIITNGPSNQTLPIKS 413
+D +C A N AG R LTV D +T + +
Sbjct: 6400 SD-EGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGE 6458
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
F TPE ++ W G+ L + +++ DG + + D SD+G Y
Sbjct: 6459 SVTFEARVQGTPEEVL-WMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVR 6517
Query: 471 SRHGKYVWSGALLV 484
S+ V +L+V
Sbjct: 6518 SKGTNLVSVASLVV 6531
Score = 68.1 bits (159), Expect = 4e-11
Identities = 57/180 (31%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178
G V EC GSP P W K + L+ S+ L++ G+ L+I D DA Y
Sbjct: 5408 GRCVTFEC-EISGSPRPEYRWFKGCKELV--DTSKYTLINKGDKQVLIINDLTSDDADEY 5464
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLW 235
C A N++GTR S A L+I KP + P+ AQ G ++ + P + W
Sbjct: 5465 TCRATNSSGTR-STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARW 5523
Query: 236 RRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ DD +LR+ N D GEY ENSVG+ S + +TV D P
Sbjct: 5524 TKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVP 5583
Score = 67.3 bits (157), Expect = 6e-11
Identities = 63/206 (30%), Positives = 93/206 (45%), Gaps = 32/206 (15%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G PEP + W NG+ + + DSR ++ L I DA+++D G+Y C A N+AG +E
Sbjct: 6359 GQPEPLIEWLHNGERIS-ESDSRFRASYVAGKATLRISDAKKSDEGQYLCRASNSAG-QE 6416
Query: 191 SAIATLKIHIKPYLITGPE---------------DVVAQTGSSVTFQCRVGGDPLPDVLW 235
ATL + L+ G + G SVTF+ RV G P +VLW
Sbjct: 6417 QTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGESVTFEARVQGTP-EEVLW 6475
Query: 236 RRSAGGGNMPLG-RVKVLDDG---SLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTV- 289
R+ G + G + + DG S +++ +D G Y E + VS + + V
Sbjct: 6476 MRN--GQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVRSKGTNLVSVASLVVVG 6533
Query: 290 --YDPPSINLSPNSVNVESGNVARFT 313
DPP L P+SV+ G FT
Sbjct: 6534 EKADPPVTRL-PSSVSAPLGGSTAFT 6558
Score = 66.1 bits (154), Expect = 1e-10
Identities = 123/504 (24%), Positives = 191/504 (37%), Gaps = 63/504 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186
+P G P P V W + +G R+ L + LV++ + D+G + A NA
Sbjct: 2465 VPVSGEPAPTVTWHWPDNREIRNG-GRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNAN 2523
Query: 187 GTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRR--S 238
G E AT+KI++ KP GP DV G VT R GG P+ + + + +
Sbjct: 2524 GEDE---ATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDT 2580
Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDP--- 292
A G +P +V D + +D +I E ++ A N+ G + G DP
Sbjct: 2581 ASGRWVPAAKVAG-DKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDK 2639
Query: 293 PSINLSPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P +P + + +V + A P + VE F D H A
Sbjct: 2640 PGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDE--FSPFWNDVAHVPAGQT 2697
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
TV + + K + R A N AG + + PP+I S Q + +
Sbjct: 2698 NATVGNLKEGSKYEFR----IRAKNKAGLGDPSDSASAVAKARNVPPVIDRN-SIQEIKV 2752
Query: 412 KSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRNVTN-DG--TLVLKDLDKSDSGTYT 466
K+ F + P P I W FEG + + R + N DG +K +SD+GTY
Sbjct: 2753 KAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 2812
Query: 467 CVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
A + +G + V D P +P GP +T N+ L+W
Sbjct: 2813 IKAENENGTDTAEVKVTVLDHPSSPR-------------GP--LDVT-NIVKDGCDLAWK 2856
Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585
+ G + I Y +E ++ +G W T++ V L G Y F
Sbjct: 2857 EPEDDGGAEISHYVIE--KQDAATGR--------WTACGES-KDTNFHVDDLTQGHEYKF 2905
Query: 586 IVRTENSHGLSGPSPVSDSVTVGD 609
V+ N HG S P +++ D
Sbjct: 2906 RVKAVNRHGDSDPLEAREAIIAKD 2929
Score = 64.1 bits (149), Expect = 6e-10
Identities = 80/312 (25%), Positives = 116/312 (37%), Gaps = 45/312 (14%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + P A FTC A GRPEPT W G P SR ++ A+ DG
Sbjct: 5004 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRE---LPESSRYRFEAS---DG 5057
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
V TI + D+ V N GS L V + PP+I N LP
Sbjct: 5058 VYKFTIKEVWDIDAGEYTV-EVSNPYGSDTATANLVVQA-----PPVIEKDVPNTILPSG 5111
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEA-----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
+ YF G A L+ N + T+ + + D T
Sbjct: 5112 DLVRLKI------------YFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPA 5159
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQ 526
++ G+Y ++ + + F+ +V+ LP P P+ N+ ++ TLSW
Sbjct: 5160 LSVREAGRYEYT---VSNDSGEATTGFW--LNVTGLPEAPQGPLHISNIGPSTATLSWRP 5214
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
G S I Y VE + LS + WV + V +Y+V L Y F
Sbjct: 5215 PVTDGGSKITSYVVE---KRDLSKDE-------WVTVTSNVKDMNYIVTGLFENHEYEFR 5264
Query: 587 VRTENSHGLSGP 598
V +N +G+ P
Sbjct: 5265 VSAQNENGIGAP 5276
Score = 60.9 bits (141), Expect = 5e-09
Identities = 84/305 (27%), Positives = 118/305 (38%), Gaps = 30/305 (9%)
Query: 2 SDDYVT--SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHR 58
+DD T + E P Q D A + G P P I W G + SD+
Sbjct: 6322 ADDLKTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRF 6381
Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV------------AVL 106
G LR + + SD G Y C A+NS G ++R ATL V +
Sbjct: 6382 RASYVAGKATLRISDAK-KSDEGQYLCRASNSAGQEQTR-ATLTVKGDQPLLNGHAGQAV 6439
Query: 107 REEFRLEPE--SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
E R+ + G++V E +G+PE V W +NGQ L +GD DG
Sbjct: 6440 ESELRVTKHLGGEIVNNGESVTFEA-RVQGTPE-EVLWMRNGQELT-NGDKTSISQDGET 6496
Query: 165 L--VIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGSSV 219
L I A +DAG YQ R + GT ++A+L + P + P V A G S
Sbjct: 6497 LSFTINSADASDAGHYQLEVR-SKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGST 6555
Query: 220 TFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
F V W R + N + VK + L + NV D+G Y +
Sbjct: 6556 AFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKE 6615
Query: 278 VGAVS 282
A++
Sbjct: 6616 KKAIA 6620
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SG AP I+E P +VTV ++ A L C+ GSP+P RW+KG V+S + G
Sbjct: 447 SGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEH 506
Query: 68 FLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
+ + S D G Y N +GT + L + +FR + ++S G
Sbjct: 507 TVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTSDNGLDFRAMLKHRESQAG 562
Score = 56.0 bits (129), Expect = 2e-07
Identities = 83/317 (26%), Positives = 122/317 (38%), Gaps = 41/317 (12%)
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
++L V++G T T P+P + W+ EG + + D T
Sbjct: 3920 LDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLA----------GVETTDSQT 3969
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
L I T ++DS + AVN G + K+TV D+P P N T P S
Sbjct: 3970 KLVIPSTRRSDS-GPVKIKAVNPYGEAEANIKITVI---DKP-----GAPENITYPAVSR 4020
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
CT A +G A I ++ G+ + + SGT V HG
Sbjct: 4021 HT--CTLNWD-----APKDDGGAEIAGYKIEYQEVGSQIWDKVPGLISGTAYTVRGLEHG 4073
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVT--DTS-VTLSWSQNNKI 530
+ + + ++ + + + V P PP P T +T DT+ V+L+W+
Sbjct: 4074 QQ-YRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQVSLAWNPPRDD 4132
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
G S ILGY VE F + R W + V T +V L TY F VR
Sbjct: 4133 GGSPILGYVVERFEK---------RGGGDWAPVKMPMVKGTECIVPGLHENETYQFRVRA 4183
Query: 590 ENSHGLSGPSPVSDSVT 606
N+ G PS S+ VT
Sbjct: 4184 VNAAGHGEPSNGSEPVT 4200
Score = 54.0 bits (124), Expect = 6e-07
Identities = 114/486 (23%), Positives = 176/486 (36%), Gaps = 52/486 (10%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+P G P P + W G + D +++ DG ++ A ++D G Y A N GT
Sbjct: 2762 IPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENGT 2821
Query: 189 RESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGN 243
++A + + P GP DV + + G + ++ GG + V+ ++ A G
Sbjct: 2822 -DTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISHYVIEKQDAATGR 2880
Query: 244 MPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSP 299
G K D + +D++ E ++ +A N G + A + DP P
Sbjct: 2881 WTACGESK---DTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEAREAIIAKDPFDRADKP 2937
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ + + T P +EG + S D A V G T++
Sbjct: 2938 GTPEIVDWDKDHADLKWTP-PADDGGAPIEGY-LVEMRTPSGDWVPAVTVGAGELTATVD 2995
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+ V A+N AG S + V P I + Q + F
Sbjct: 2996 GLKPGQTYQFRV-KALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNF 3054
Query: 418 PCTAICTPEPIIAWYFEGEALIQN---HRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRH 473
P P I W+ G L H N T++ T L K ++DSG Y VA++
Sbjct: 3055 DVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNES 3114
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGS 532
GK + ++ NI +PG P P+ H ++T SV L W + G
Sbjct: 3115 GK--------DEHEVDVNI--------LDIPGAPEGPLRHKDITKESVVLKWDEPLDDGG 3158
Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
S I Y VE ++ G WV T V L G Y F V+ N
Sbjct: 3159 SPITNYVVE---KQEDGGR--------WVPCG-ETSDTSLKVNKLSEGHEYKFRVKAVNR 3206
Query: 593 HGLSGP 598
G S P
Sbjct: 3207 QGTSAP 3212
Score = 51.6 bits (118), Expect = 3e-06
Identities = 110/454 (24%), Positives = 173/454 (38%), Gaps = 65/454 (14%)
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI------KPYLITGPEDVVAQTGSSVT 220
+ R+ + ++ +A NAAG ++ + I I +P ++ PED
Sbjct: 4963 VDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAV 5022
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKV-LDDGSLR--LDNVILADEGEYSCEAEN 276
F C G P P W R+ G +P R + DG + + V D GEY+ E N
Sbjct: 5023 FTCEAVGRPEPTARWLRN--GRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSN 5080
Query: 277 SVGAVSASGYLTVYDPPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
G+ +A+ L V PP I PN++ + SG++ R +G + +++
Sbjct: 5081 PYGSDTATANLVVQAPPVIEKDVPNTI-LPSGDLVRLKIYFSG--------TAPFRHSLV 5131
Query: 336 FPGMSRDKYHAT---AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
D H T FD ++TI ++ + N +G + L VT
Sbjct: 5132 LNREEIDMDHPTIRIVEFDDHILITIPALSVREA-GRYEYTVSNDSGEATTGFWLNVTGL 5190
Query: 393 DDRP--PPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN- 448
+ P P I+N GPS TL + P T I ++ E L ++ VT+
Sbjct: 5191 PEAPQGPLHISNIGPSTATLSWRP----PVTD--GGSKITSYVVEKRDLSKDEWVTVTSN 5244
Query: 449 --DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPG 505
D ++ L ++ + A + +G GA LV + PI + F
Sbjct: 5245 VKDMNYIVTGLFENHEYEFRVSAQNENG----IGAPLVSEHPIIARLPF----------D 5290
Query: 506 PPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
PPT P+ + VTLSW + G + GY VE E +N
Sbjct: 5291 PPTSPLNLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPS---- 5346
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
+Y V +LI G Y + V N GLS
Sbjct: 5347 -----PPNNYNVPNLIDGRKYRYRVFAVNDAGLS 5375
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/209 (22%), Positives = 82/209 (39%), Gaps = 17/209 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P +++ D+ + G VTF+C + G P P+ W + + + +++ G L
Sbjct: 5394 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGC-KELVDTSKYTLINKGDKQVLI 5452
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCT 315
++++ D EY+C A NS G S L + P + + P + G
Sbjct: 5453 INDLTSDDADEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIP 5512
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
P+ W+ +G + + K+ T D L I++ + D V
Sbjct: 5513 YKAYPQGEARWTKDGEKI-----ENNSKFSIT-TDDKFATLRISNASREDYGEYRVV-VE 5565
Query: 376 NYAGSSFVRGKLTVTSDDDRPP--PIITN 402
N GS +TV +D PP PII N
Sbjct: 5566 NSVGSDSGTVNVTV-ADVPEPPRFPIIEN 5593
Score = 49.2 bits (112), Expect = 2e-05
Identities = 51/221 (23%), Positives = 81/221 (36%), Gaps = 10/221 (4%)
Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNL 165
R + ++PE V C G PEP W +NG+ L R DG
Sbjct: 5003 RPQIVVKPEDTAQPYNRRAVFTC-EAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKF 5061
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
I++ DAG Y N G+ ++A A L + P + + + +G V +
Sbjct: 5062 TIKEVWDIDAGEYTVEVSNPYGS-DTATANLVVQAPPVIEKDVPNTILPSGDLVRLKIYF 5120
Query: 226 GGD-PL-PDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVILADEGEYSCEAENSVGAVS 282
G P ++ R + P R+ DD L + + + + G Y N G +
Sbjct: 5121 SGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEAT 5180
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
+L V P P ++ N+ T T + RP T
Sbjct: 5181 TGFWLNVTGLPEAPQGPLHIS----NIGPSTATLSWRPPVT 5217
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 32/185 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVWSGA 481
P+PII + + +N R V N G +V+ +SD+G Y A++++GK
Sbjct: 4338 PKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCK-- 4395
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQV 540
++ F V PG PT PI ++ ++TLSW G +I Y V
Sbjct: 4396 ----------LNVF----VLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAITNYVV 4441
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E + T G+ WV + V T V++L Y F VR EN +G+ P
Sbjct: 4442 E---KRTPGGD--------WVTVGHPVGTT-LRVRNLDANTPYEFRVRAENQYGVGEPLE 4489
Query: 601 VSDSV 605
D++
Sbjct: 4490 TDDAI 4494
Score = 48.4 bits (110), Expect = 3e-05
Identities = 24/91 (26%), Positives = 51/91 (56%), Gaps = 4/91 (4%)
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVI 263
G +D+ + G ++ + + G+PLP+ LW + G +GRVK+ + ++++N +
Sbjct: 1272 GIKDLRLKVGETIKYDVPISGEPLPECLWVVN-GKPLKAVGRVKMSSERGKHIMKIENAV 1330
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
AD G+++ +NS G+ ++ +TV P+
Sbjct: 1331 RADSGKFTITLKNSSGSCDSTATVTVVGRPT 1361
Score = 47.6 bits (108), Expect = 5e-05
Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 12/181 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
G+T+ + +P G P P W NG+ L G +M G +++ I++A + D+G++
Sbjct: 1281 GETIKYD-VPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1339
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQ--CRVGGDPLPDVLWR 236
+N++G+ +S AT+ + +P GP D+ V G+++++ GGDPL +
Sbjct: 1340 TLKNSSGSCDST-ATVTVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVE 1398
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS--CEAENSVG---AVSASGYLTVYD 291
V +D + L L ++G Y +A N+ G +SA Y + D
Sbjct: 1399 AQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKD 1458
Query: 292 P 292
P
Sbjct: 1459 P 1459
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 7/100 (7%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVI 263
+ + + G++V ++ ++GG+P+P+V W + G + G +D L + + +
Sbjct: 1570 KSITVKAGATVRWEVKIGGEPIPEVKWFK--GNQQLENGIQLTIDTRKNEHTILCIPSAM 1627
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
+D GEY +NS GA LTV D PS P V+
Sbjct: 1628 RSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVS 1667
Score = 43.6 bits (98), Expect = 9e-04
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 6/97 (6%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLV 453
P T S+ + A F PEP+I W GE + ++ R V TL
Sbjct: 6334 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6393
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPI 488
+ D KSD G Y C AS+ G+ L V D P+
Sbjct: 6394 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPL 6430
Score = 42.7 bits (96), Expect = 0.002
Identities = 117/488 (23%), Positives = 174/488 (35%), Gaps = 59/488 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188
+P RG P P W N + + D R+ D V++ A + AG Y A NA+G+
Sbjct: 1880 VPVRGEPPPKKEWIFNEKPV-DDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGS 1938
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGG 242
+ ++ + + KP GP +V + +V GG P+ ++ A G
Sbjct: 1939 DKHSVEVIVLG-KPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATGR 1997
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+P GR + + N+ E ++ A N G S LT + L+ N
Sbjct: 1998 WVPCGRSETT---KTTVPNLQPGHEYKFRVRAVNKEG---ESDPLTT---NTAILAKNPY 2048
Query: 303 NVESGNVARFTCTATGRPEPTMFWSV--EGNRTI-IFPGMSRDK---YHATAVFDGVTVL 356
V G V + + + W+ +G I F +DK + V G
Sbjct: 2049 EV-PGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQKT 2107
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
K SA N AG+ V + P I S+ T+ + +
Sbjct: 2108 ATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGAT 2167
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASS 471
F P P + W F G+ I + + N+ L + SG YT A++
Sbjct: 2168 LKFIVHIDGEPAPDVTWSFNGKG-IGESKAQIENEPYISRFALPKALRKQSGKYTITATN 2226
Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKI 530
+G DS + NI V S P P PI +V + TL W
Sbjct: 2227 ING---------TDS-VTINI------KVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDD 2270
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G I Y++E T G WV R TH+ V SL G Y F V+
Sbjct: 2271 GGEPIEFYEIE--KMNTKDGI--------WVPCGRS-GDTHFTVDSLNKGDHYKFRVKAV 2319
Query: 591 NSHGLSGP 598
NS G S P
Sbjct: 2320 NSEGPSDP 2327
Score = 42.7 bits (96), Expect = 0.002
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ G P I+ +P D ++ A C A G P P RW + G + + + G+
Sbjct: 4999 SGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGV 5058
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGT 93
+ + T V DAG Y E +N YG+
Sbjct: 5059 Y--KFTIKEVWDIDAGEYTVEVSNPYGS 5084
Score = 41.5 bits (93), Expect = 0.004
Identities = 45/153 (29%), Positives = 66/153 (43%), Gaps = 15/153 (9%)
Query: 178 YQCIARNAAGTRESAIATLKIHI-----KPYLITG--PEDVVAQTGSSVTFQCRVGGDPL 230
++ A NAAG E ++ ++ I +P + G D++A G P
Sbjct: 4575 FRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPA 4634
Query: 231 PDVLWRRSAGGGNMPLGRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P V + + + RVKV D +L ++ L D G Y E ENS G+ SAS L
Sbjct: 4635 PKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQGSDSASIRL 4694
Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D P+ SP + VE ++A CT P
Sbjct: 4695 KVVDKPA---SPQHIRVE--DIAPDCCTLYWMP 4722
Score = 40.3 bits (90), Expect = 0.008
Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 18/147 (12%)
Query: 178 YQCIARNAAGTRE----SAIATLK-IHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDP 229
Y+ +A N AG + SA AT K +H P + G E V + G + P
Sbjct: 3887 YRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRV-KAGEPLVITIPFTASP 3945
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
PD+ W + G PL V+ D + L + + +D G +A N G A+ +T
Sbjct: 3946 QPDISWTKEGG---KPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKIT 4002
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCT 315
V D P +P ++ + V+R TCT
Sbjct: 4003 VIDKPG---APENITYPA--VSRHTCT 4024
Score = 39.9 bits (89), Expect = 0.011
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P P +T S L+W++ + G + I GY VE ++ L N+ R +
Sbjct: 4208 PGAPDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVE---KKKLGDNDWTRCN------ 4258
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
+ V T + VK+L Y F V NS G PS SD V +
Sbjct: 4259 DKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLI 4302
Score = 39.5 bits (88), Expect = 0.014
Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 6/127 (4%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCR-AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G + I D+TV + + AGG+P P I + G + + R+++
Sbjct: 4307 GRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIF-ENERTVVDVNPGE 4365
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESKQSAQGDTVV 126
+ T G SDAG Y ATN YG L+V VL + P Q D +
Sbjct: 4366 IVITTTGSKRSDAGPYKISATNKYG---KDTCKLNVFVLDAPGKPTGPIRATDIQADAMT 4422
Query: 127 LECLPPR 133
L PP+
Sbjct: 4423 LSWRPPK 4429
Score = 38.7 bits (86), Expect = 0.025
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 8/102 (7%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P P ++ TL W + G S I Y VE G W +
Sbjct: 4700 PASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGK--------WEKV 4751
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
+ V +Y V LI Y F VR E +G+S P ++D V
Sbjct: 4752 SSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVV 4793
Score = 38.7 bits (86), Expect = 0.025
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
+++ AP+ + + ++ L C G+P+P I W K G V D +
Sbjct: 6170 EEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDED-RVQVSF 6228
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G+ L + RV DAG Y ATN G
Sbjct: 6229 RSGVCSLEIFNARV-DDAGTYTVTATNDLG 6257
Score = 37.5 bits (83), Expect = 0.057
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I P +V V A TC +G P PT W +G+R +I G R K+
Sbjct: 451 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRW-FKGSREVISGG--RFKHITDGKEHT 507
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
V + + +++ T+ V+ S+ V KL VTSD+
Sbjct: 508 VALALLKCRSQDEGPYTLTIENVHGTDSADV--KLLVTSDN 546
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 11/111 (9%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P P P+ +VT S L+W G + I Y VE R+T + NT
Sbjct: 3710 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVVE--KRDTKT--NT----- 3760
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
WV ++ V T V L G Y F V EN+ G S + V D
Sbjct: 3761 -WVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKD 3810
Score = 36.7 bits (81), Expect = 0.10
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-----S 256
P ++ PE+V + C+V G P P W + + + GR K + DG +
Sbjct: 451 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGS-REVISGGRFKHITDGKEHTVA 509
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L L DEG Y+ EN G SA L V
Sbjct: 510 LALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 542
Score = 36.3 bits (80), Expect = 0.13
Identities = 72/307 (23%), Positives = 115/307 (37%), Gaps = 29/307 (9%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
ATL + + W+ G + + + + L R+ D G Y C
Sbjct: 802 ATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIE-DHGEYKCT-- 858
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T R + + +F + + + + D V L C + + P + W +NG+
Sbjct: 859 ----TKDDRTMAQLIVDAKNKFIVALKDTEVIEKDDVTLMC-QTKDTKTPGI-WFRNGKQ 912
Query: 149 L--LFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYL 204
+ + G +G + L I +A Y+ + AG R S + L+ +P L
Sbjct: 913 ISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEI---DQAGLRGSCNVTVLEAEKRPIL 969
Query: 205 ITGPEDVVAQTGS----SVTFQCRVG--GDPLPDVLWRRSAGGGNM-PLGRVKVLDD-GS 256
P+ + A+ G V FQ + GDP +L M L V + DD
Sbjct: 970 NWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVIIKDDVAE 1029
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV-ARFTCT 315
+ N LAD G+++ E NS G A L V D P P +E+ NV A
Sbjct: 1030 IVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKP----KPPKGPLETKNVTAEGLDL 1085
Query: 316 ATGRPEP 322
G P+P
Sbjct: 1086 VWGTPDP 1092
Score = 36.3 bits (80), Expect = 0.13
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLR 258
+P I P G S F CRV P V W + + +K + D L
Sbjct: 6055 QPRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGLT 6114
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ V D+GEY+ A+NS G +L V
Sbjct: 6115 INRVKGDDKGEYTVRAKNSYGTKEEIVFLNV 6145
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 12/102 (11%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P P + T L W G S I+GYQV+ R+T SG W+
Sbjct: 4801 VPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQY--RDTSSGR--------WIN 4849
Query: 563 IARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+ Q H V L + F + +N+ G S PSP S+
Sbjct: 4850 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSE 4891
Score = 35.1 bits (77), Expect = 0.31
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 11/100 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P + + ++W +K G + I Y VEV +T + W +
Sbjct: 1463 PGKPGRPEITDFDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDT----------KEWKEV 1512
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+RV T+ + L G Y F VR N G PS S+
Sbjct: 1513 -KRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSE 1551
Score = 35.1 bits (77), Expect = 0.31
Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 33/186 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P+ W + R +VTN T + + + D+G Y + + HGK
Sbjct: 3356 PAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYKIIVENEHGK------ 3409
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQV 540
N+ V +PG P P+ + TL+W G + +L Y V
Sbjct: 3410 ----DTAQCNV------TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIV 3459
Query: 541 EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
E SRG W + T V K L+PG Y F V+ N G S P
Sbjct: 3460 EKMD-----------TSRGTWQEVGTFPDCTAKVNK-LVPGKEYAFRVKAVNLQGESKPL 3507
Query: 600 PVSDSV 605
+ +
Sbjct: 3508 EAEEPI 3513
Score = 35.1 bits (77), Expect = 0.31
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P ++ ++TL W++ G + I GY +E RE S W
Sbjct: 4503 PGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIE--KREV--------GSTEWTKA 4552
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
A + T + V L P TY F V N+ G
Sbjct: 4553 AFGNILDTKHRVTGLTPKKTYEFRVAAYNAAG 4584
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/94 (27%), Positives = 32/94 (34%), Gaps = 5/94 (5%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TL 452
P I P N T+ A+ C +P P W+ +I R DG L
Sbjct: 451 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVAL 510
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
L D G YT + HG LLV S
Sbjct: 511 ALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTS 544
Score = 34.7 bits (76), Expect = 0.40
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 1/74 (1%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++ V Q +LN G P+P I W G V SD + G + SD
Sbjct: 2749 EIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRA-LRSD 2807
Query: 80 AGVYWCEATNSYGT 93
G Y +A N GT
Sbjct: 2808 TGTYIIKAENENGT 2821
Score = 34.7 bits (76), Expect = 0.40
Identities = 35/152 (23%), Positives = 61/152 (40%), Gaps = 15/152 (9%)
Query: 178 YQCIARNAAGTRESAIAT-----LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
++ IA NAAG + + T ++KP ++T + + G + + G P P
Sbjct: 3592 FRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPDPT 3651
Query: 233 VLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
W + G L ++D S+ + AD G Y + +N +G A +
Sbjct: 3652 ATW--TVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGEDEAIFEVI 3709
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D PS P +E +V + +C +P
Sbjct: 3710 VQDRPSAPEGP----LEVSDVTKDSCVLNWKP 3737
Score = 33.5 bits (73), Expect = 0.93
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 13/114 (11%)
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNVESGNVAR 311
+L ++N + D G+Y+CEA V LTV +PP +N PN+ + A
Sbjct: 656 TLIINNPEVDDTGKYTCEA----NGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAV 711
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
TC P + W G++ I G R AV G LTI + +++D
Sbjct: 712 LTC-KVNTPRAPLVW-YRGSKA-IQEGDPRFIIEKDAV--GRCTLTIKEVEEDD 760
Score = 32.7 bits (71), Expect = 1.6
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 12/100 (12%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P PP P+ T NVT + L W + + + Y +E+ +E SGN
Sbjct: 1062 VKDKPKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEM--QEGRSGN------- 1112
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
W + T + VK L Y F V+ N GLS P
Sbjct: 1113 -WAKVGE-TKGTDFKVKDLKEHGEYKFRVKALNECGLSDP 1150
Score = 32.3 bits (70), Expect = 2.2
Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 1/83 (1%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV + GG P P ++W+KG + + +I + + SD
Sbjct: 1572 ITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDV 1631
Query: 81 GVYWCEATNSYGTARSRNATLHV 103
G Y NS+G A A L V
Sbjct: 1632 GEYRLTVKNSHG-ADEEKANLTV 1653
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 11/101 (10%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P KP + + + W+ G + + GY VE + S W
Sbjct: 3521 VPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVE----------KKEKGSAIWTE 3570
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
A + T + +L PG+ Y F V N+ G S PS +D
Sbjct: 3571 -AGKTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTD 3610
Score = 32.3 bits (70), Expect = 2.2
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
+ D P P +E+ + + L W PP+ +G N VV D N + V ++
Sbjct: 3710 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPK---DDGGAEISNYVVEKRDTKTN-TWVPVS 3765
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
V TS+ + LT G Y ++ AE G
Sbjct: 3766 AFV-TGTSITVPKLTEGHEYEFRVMAENTFG 3795
Score = 31.9 bits (69), Expect = 2.9
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 12/94 (12%)
Query: 504 PGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
P P P+ +V + ++ LSW + G I Y+VE +T +G WV
Sbjct: 1657 PSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVE--KLDTATGR--------WVP 1706
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
A +V T + L G TY F V+ N G S
Sbjct: 1707 CA-KVKDTKAHIDGLKKGQTYQFRVKAVNKEGAS 1739
Score = 31.1 bits (67), Expect = 5.0
Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 11/111 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PGPP ++ T++W + G S I GY VE+ RE S W V
Sbjct: 4902 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEI--RE--------YGSTLWTVA 4951
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ V + + V L Y F V N+ G PS S + + + S
Sbjct: 4952 SDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5002
Score = 30.3 bits (65), Expect = 8.7
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 11/123 (8%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD---DGSLRLD 260
+ G D+ + G+ + G+P P W+ A + G R V + ++ +
Sbjct: 3332 LAGLLDLRIKAGTPIKLDIAFEGEPAPVAKWK--ANDATIDTGARADVTNTPTSSAIHIF 3389
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ + D G Y EN G +A +TV D P P ++ + + CT +P
Sbjct: 3390 SAVRGDTGVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKID----EIHKEGCTLNWKP 3445
Query: 321 EPT 323
PT
Sbjct: 3446 -PT 3447
>Z73897-5|CAA98065.2| 7158|Caenorhabditis elegans Hypothetical protein
ZK617.1b protein.
Length = 7158
Score = 76.6 bits (180), Expect = 1e-13
Identities = 86/324 (26%), Positives = 130/324 (40%), Gaps = 44/324 (13%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + +N E G F C +G P P W +G + ++ KY T + G
Sbjct: 5923 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRW-FKGCKELV----DTSKY--TLINKG 5975
Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLP 410
VL IND +D+ + C A N +G+ R L + T PP G Q
Sbjct: 5976 DKQVLIINDLTSDDA-DEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGE 6034
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTC 467
+ + P A P+ W +GE + N + ++T D TL + + + D G Y
Sbjct: 6035 TIELKI-PYKAY--PQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRV 6091
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
V + G SG + V V+ +P PP PI N+ D +V LSW
Sbjct: 6092 VVENSVGSD--SGTVNVT--------------VADVPEPPRFPIIENILDEAVILSWKPP 6135
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
G S + Y +E RE + G+ +P + T+ ++ L G Y F +
Sbjct: 6136 ALDGGSLVTNYTIE--KREAMGGSWSP---------CAKSRYTYTTIEGLRAGKQYEFRI 6184
Query: 588 RTENSHGLSGP-SPVSDSVTVGDD 610
EN HG S P P + + GD+
Sbjct: 6185 IAENKHGQSKPCEPTAPVLIPGDE 6208
Score = 73.7 bits (173), Expect = 7e-13
Identities = 52/192 (27%), Positives = 88/192 (45%), Gaps = 12/192 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SGE P I+ D+ + T C GSP P RW+KG +V + +++ G
Sbjct: 5919 SGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQ 5978
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDT 124
L + DA Y C ATNS GT RS A L + F + P+ ++ +G+T
Sbjct: 5979 VL-IINDLTSDDADEYTCRATNSSGT-RSTRANLRIKTKPRVF-IPPKYHGGYEAQKGET 6035
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCI 181
+ L+ +P + P+ W K+G+ + + +S+ + L I +A + D G Y+ +
Sbjct: 6036 IELK-IPYKAYPQGEARWTKDGEKI--ENNSKFSITTDDKFATLRISNASREDYGEYRVV 6092
Query: 182 ARNAAGTRESAI 193
N+ G+ +
Sbjct: 6093 VENSVGSDSGTV 6104
Score = 72.9 bits (171), Expect = 1e-12
Identities = 121/493 (24%), Positives = 190/493 (38%), Gaps = 72/493 (14%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G P P+V W NG+ + G+S+ + + + A + +G+Y A N GT +
Sbjct: 2705 GEPAPDVTWSFNGKGI---GESKAQIENEPYISRFALPKALRKQSGKYTITATNINGT-D 2760
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGGNM 244
S +K+ KP GP +V T + GG+P+ ++ + G +
Sbjct: 2761 SVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWV 2820
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT------VYDPPSINLS 298
P GR D +D++ D ++ +A NS G T +D P
Sbjct: 2821 PCGRS---GDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGR 2877
Query: 299 PNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH----ATAVFDGV 353
P + +S +V ++ + P + +E R KY A V G
Sbjct: 2878 PEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIE----------KRTKYGRWEPAITVPGGQ 2927
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPI 411
T T+ D N+ V AVN G S K + + P I + N T+
Sbjct: 2928 TTATVPDLTPNEEYEFRVV-AVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKA 2986
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTC 467
F P P + W++ I+N R N LV+K +++ DSGT+T
Sbjct: 2987 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTI 3046
Query: 468 VASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
A + +G+ + + ++D P +PN DVS + G VTL+W
Sbjct: 3047 KAVNANGEDEATVKINVIDKPTSPN----GPLDVSDVHG------------DHVTLNWRA 3090
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV-HQTHYVVKSLIPGITYMF 585
+ G I Y +E + +T SG WV A+ +T VV LIPG Y F
Sbjct: 3091 PDDDGGIPIENYVIEKY--DTASGR--------WVPAAKVAGDKTTAVVDGLIPGHEYKF 3140
Query: 586 IVRTENSHGLSGP 598
V N+ G S P
Sbjct: 3141 RVAAVNAEGESDP 3153
Score = 72.1 bits (169), Expect = 2e-12
Identities = 118/494 (23%), Positives = 170/494 (34%), Gaps = 39/494 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I +P V Q A CR S P + W+K + G + L
Sbjct: 6585 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGL-- 6642
Query: 72 THGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLEC 129
T RV D G Y A NSYGT + L+V E + EP E + A V E
Sbjct: 6643 TINRVKGDDKGEYTVRAKNSYGT-KEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVEEF 6701
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ---DARQTDAGRYQCIARNAA 186
R +P + + L N I+ D D R Q R+
Sbjct: 6702 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGV 6761
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+ E A + Y +T D+ V GG+P+P V R P
Sbjct: 6762 CSLEIFNARVD-DAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRVSSFR-------PR 6813
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVN 303
L G+ + AD S + S SA+ L + PS +
Sbjct: 6814 RAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSFTAQLSDSE 6873
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
E G A F+ +G+PEP + W G R S ++ A+ V G L I+D K
Sbjct: 6874 TEVGGSAEFSAAVSGQPEPLIEWLHNGERI----SESDSRFRASYV-AGKATLRISDAKK 6928
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD----------RPPPIITNGPSNQTLPIKS 413
+D +C A N AG R LTV D +T + +
Sbjct: 6929 SD-EGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGE 6987
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
F TPE ++ W G+ L + +++ DG + + D SD+G Y
Sbjct: 6988 SVTFEARVQGTPEEVL-WMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVR 7046
Query: 471 SRHGKYVWSGALLV 484
S+ V +L+V
Sbjct: 7047 SKGTNLVSVASLVV 7060
Score = 68.1 bits (159), Expect = 4e-11
Identities = 57/180 (31%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178
G V EC GSP P W K + L+ S+ L++ G+ L+I D DA Y
Sbjct: 5937 GRCVTFEC-EISGSPRPEYRWFKGCKELV--DTSKYTLINKGDKQVLIINDLTSDDADEY 5993
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLW 235
C A N++GTR S A L+I KP + P+ AQ G ++ + P + W
Sbjct: 5994 TCRATNSSGTR-STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARW 6052
Query: 236 RRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ DD +LR+ N D GEY ENSVG+ S + +TV D P
Sbjct: 6053 TKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVP 6112
Score = 67.3 bits (157), Expect = 6e-11
Identities = 63/206 (30%), Positives = 93/206 (45%), Gaps = 32/206 (15%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G PEP + W NG+ + + DSR ++ L I DA+++D G+Y C A N+AG +E
Sbjct: 6888 GQPEPLIEWLHNGERIS-ESDSRFRASYVAGKATLRISDAKKSDEGQYLCRASNSAG-QE 6945
Query: 191 SAIATLKIHIKPYLITGPE---------------DVVAQTGSSVTFQCRVGGDPLPDVLW 235
ATL + L+ G + G SVTF+ RV G P +VLW
Sbjct: 6946 QTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGESVTFEARVQGTP-EEVLW 7004
Query: 236 RRSAGGGNMPLG-RVKVLDDG---SLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTV- 289
R+ G + G + + DG S +++ +D G Y E + VS + + V
Sbjct: 7005 MRN--GQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVRSKGTNLVSVASLVVVG 7062
Query: 290 --YDPPSINLSPNSVNVESGNVARFT 313
DPP L P+SV+ G FT
Sbjct: 7063 EKADPPVTRL-PSSVSAPLGGSTAFT 7087
Score = 66.1 bits (154), Expect = 1e-10
Identities = 123/504 (24%), Positives = 191/504 (37%), Gaps = 63/504 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186
+P G P P V W + +G R+ L + LV++ + D+G + A NA
Sbjct: 2994 VPVSGEPAPTVTWHWPDNREIRNG-GRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNAN 3052
Query: 187 GTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRR--S 238
G E AT+KI++ KP GP DV G VT R GG P+ + + + +
Sbjct: 3053 GEDE---ATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDT 3109
Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDP--- 292
A G +P +V D + +D +I E ++ A N+ G + G DP
Sbjct: 3110 ASGRWVPAAKVAG-DKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDK 3168
Query: 293 PSINLSPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P +P + + +V + A P + VE F D H A
Sbjct: 3169 PGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDE--FSPFWNDVAHVPAGQT 3226
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
TV + + K + R A N AG + + PP+I S Q + +
Sbjct: 3227 NATVGNLKEGSKYEFR----IRAKNKAGLGDPSDSASAVAKARNVPPVIDRN-SIQEIKV 3281
Query: 412 KSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRNVTN-DG--TLVLKDLDKSDSGTYT 466
K+ F + P P I W FEG + + R + N DG +K +SD+GTY
Sbjct: 3282 KAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 3341
Query: 467 CVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
A + +G + V D P +P GP +T N+ L+W
Sbjct: 3342 IKAENENGTDTAEVKVTVLDHPSSPR-------------GP--LDVT-NIVKDGCDLAWK 3385
Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585
+ G + I Y +E ++ +G W T++ V L G Y F
Sbjct: 3386 EPEDDGGAEISHYVIE--KQDAATGR--------WTACGES-KDTNFHVDDLTQGHEYKF 3434
Query: 586 IVRTENSHGLSGPSPVSDSVTVGD 609
V+ N HG S P +++ D
Sbjct: 3435 RVKAVNRHGDSDPLEAREAIIAKD 3458
Score = 64.1 bits (149), Expect = 6e-10
Identities = 80/312 (25%), Positives = 116/312 (37%), Gaps = 45/312 (14%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + P A FTC A GRPEPT W G P SR ++ A+ DG
Sbjct: 5533 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRE---LPESSRYRFEAS---DG 5586
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
V TI + D+ V N GS L V + PP+I N LP
Sbjct: 5587 VYKFTIKEVWDIDAGEYTV-EVSNPYGSDTATANLVVQA-----PPVIEKDVPNTILPSG 5640
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEA-----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
+ YF G A L+ N + T+ + + D T
Sbjct: 5641 DLVRLKI------------YFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPA 5688
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQ 526
++ G+Y ++ + + F+ +V+ LP P P+ N+ ++ TLSW
Sbjct: 5689 LSVREAGRYEYT---VSNDSGEATTGFW--LNVTGLPEAPQGPLHISNIGPSTATLSWRP 5743
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
G S I Y VE + LS + WV + V +Y+V L Y F
Sbjct: 5744 PVTDGGSKITSYVVE---KRDLSKDE-------WVTVTSNVKDMNYIVTGLFENHEYEFR 5793
Query: 587 VRTENSHGLSGP 598
V +N +G+ P
Sbjct: 5794 VSAQNENGIGAP 5805
Score = 60.9 bits (141), Expect = 5e-09
Identities = 84/305 (27%), Positives = 118/305 (38%), Gaps = 30/305 (9%)
Query: 2 SDDYVT--SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHR 58
+DD T + E P Q D A + G P P I W G + SD+
Sbjct: 6851 ADDLKTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRF 6910
Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV------------AVL 106
G LR + + SD G Y C A+NS G ++R ATL V +
Sbjct: 6911 RASYVAGKATLRISDAK-KSDEGQYLCRASNSAGQEQTR-ATLTVKGDQPLLNGHAGQAV 6968
Query: 107 REEFRLEPE--SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
E R+ + G++V E +G+PE V W +NGQ L +GD DG
Sbjct: 6969 ESELRVTKHLGGEIVNNGESVTFEA-RVQGTPE-EVLWMRNGQELT-NGDKTSISQDGET 7025
Query: 165 L--VIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGSSV 219
L I A +DAG YQ R + GT ++A+L + P + P V A G S
Sbjct: 7026 LSFTINSADASDAGHYQLEVR-SKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGST 7084
Query: 220 TFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
F V W R + N + VK + L + NV D+G Y +
Sbjct: 7085 AFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKE 7144
Query: 278 VGAVS 282
A++
Sbjct: 7145 KKAIA 7149
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SG AP I+E P +VTV ++ A L C+ GSP+P RW+KG V+S + G
Sbjct: 976 SGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEH 1035
Query: 68 FLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
+ + S D G Y N +GT + L + +FR + ++S G
Sbjct: 1036 TVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTSDNGLDFRAMLKHRESQAG 1091
Score = 56.0 bits (129), Expect = 2e-07
Identities = 83/317 (26%), Positives = 122/317 (38%), Gaps = 41/317 (12%)
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
++L V++G T T P+P + W+ EG + + D T
Sbjct: 4449 LDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLA----------GVETTDSQT 4498
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
L I T ++DS + AVN G + K+TV D+P P N T P S
Sbjct: 4499 KLVIPSTRRSDS-GPVKIKAVNPYGEAEANIKITVI---DKP-----GAPENITYPAVSR 4549
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
CT A +G A I ++ G+ + + SGT V HG
Sbjct: 4550 HT--CTLNWD-----APKDDGGAEIAGYKIEYQEVGSQIWDKVPGLISGTAYTVRGLEHG 4602
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVT--DTS-VTLSWSQNNKI 530
+ + + ++ + + + V P PP P T +T DT+ V+L+W+
Sbjct: 4603 QQ-YRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQVSLAWNPPRDD 4661
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
G S ILGY VE F + R W + V T +V L TY F VR
Sbjct: 4662 GGSPILGYVVERFEK---------RGGGDWAPVKMPMVKGTECIVPGLHENETYQFRVRA 4712
Query: 590 ENSHGLSGPSPVSDSVT 606
N+ G PS S+ VT
Sbjct: 4713 VNAAGHGEPSNGSEPVT 4729
Score = 54.0 bits (124), Expect = 6e-07
Identities = 114/486 (23%), Positives = 176/486 (36%), Gaps = 52/486 (10%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+P G P P + W G + D +++ DG ++ A ++D G Y A N GT
Sbjct: 3291 IPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENGT 3350
Query: 189 RESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGN 243
++A + + P GP DV + + G + ++ GG + V+ ++ A G
Sbjct: 3351 -DTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISHYVIEKQDAATGR 3409
Query: 244 MPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSP 299
G K D + +D++ E ++ +A N G + A + DP P
Sbjct: 3410 WTACGESK---DTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEAREAIIAKDPFDRADKP 3466
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ + + T P +EG + S D A V G T++
Sbjct: 3467 GTPEIVDWDKDHADLKWTP-PADDGGAPIEGY-LVEMRTPSGDWVPAVTVGAGELTATVD 3524
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+ V A+N AG S + V P I + Q + F
Sbjct: 3525 GLKPGQTYQFRV-KALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNF 3583
Query: 418 PCTAICTPEPIIAWYFEGEALIQN---HRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRH 473
P P I W+ G L H N T++ T L K ++DSG Y VA++
Sbjct: 3584 DVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNES 3643
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGS 532
GK + ++ NI +PG P P+ H ++T SV L W + G
Sbjct: 3644 GK--------DEHEVDVNI--------LDIPGAPEGPLRHKDITKESVVLKWDEPLDDGG 3687
Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
S I Y VE ++ G WV T V L G Y F V+ N
Sbjct: 3688 SPITNYVVE---KQEDGGR--------WVPCG-ETSDTSLKVNKLSEGHEYKFRVKAVNR 3735
Query: 593 HGLSGP 598
G S P
Sbjct: 3736 QGTSAP 3741
Score = 51.6 bits (118), Expect = 3e-06
Identities = 110/454 (24%), Positives = 173/454 (38%), Gaps = 65/454 (14%)
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI------KPYLITGPEDVVAQTGSSVT 220
+ R+ + ++ +A NAAG ++ + I I +P ++ PED
Sbjct: 5492 VDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAV 5551
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKV-LDDGSLR--LDNVILADEGEYSCEAEN 276
F C G P P W R+ G +P R + DG + + V D GEY+ E N
Sbjct: 5552 FTCEAVGRPEPTARWLRN--GRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSN 5609
Query: 277 SVGAVSASGYLTVYDPPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
G+ +A+ L V PP I PN++ + SG++ R +G + +++
Sbjct: 5610 PYGSDTATANLVVQAPPVIEKDVPNTI-LPSGDLVRLKIYFSG--------TAPFRHSLV 5660
Query: 336 FPGMSRDKYHAT---AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
D H T FD ++TI ++ + N +G + L VT
Sbjct: 5661 LNREEIDMDHPTIRIVEFDDHILITIPALSVREA-GRYEYTVSNDSGEATTGFWLNVTGL 5719
Query: 393 DDRP--PPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN- 448
+ P P I+N GPS TL + P T I ++ E L ++ VT+
Sbjct: 5720 PEAPQGPLHISNIGPSTATLSWRP----PVTD--GGSKITSYVVEKRDLSKDEWVTVTSN 5773
Query: 449 --DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPG 505
D ++ L ++ + A + +G GA LV + PI + F
Sbjct: 5774 VKDMNYIVTGLFENHEYEFRVSAQNENG----IGAPLVSEHPIIARLPF----------D 5819
Query: 506 PPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
PPT P+ + VTLSW + G + GY VE E +N
Sbjct: 5820 PPTSPLNLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPS---- 5875
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
+Y V +LI G Y + V N GLS
Sbjct: 5876 -----PPNNYNVPNLIDGRKYRYRVFAVNDAGLS 5904
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/209 (22%), Positives = 82/209 (39%), Gaps = 17/209 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P +++ D+ + G VTF+C + G P P+ W + + + +++ G L
Sbjct: 5923 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGC-KELVDTSKYTLINKGDKQVLI 5981
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCT 315
++++ D EY+C A NS G S L + P + + P + G
Sbjct: 5982 INDLTSDDADEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIP 6041
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
P+ W+ +G + + K+ T D L I++ + D V
Sbjct: 6042 YKAYPQGEARWTKDGEKI-----ENNSKFSIT-TDDKFATLRISNASREDYGEYRVV-VE 6094
Query: 376 NYAGSSFVRGKLTVTSDDDRPP--PIITN 402
N GS +TV +D PP PII N
Sbjct: 6095 NSVGSDSGTVNVTV-ADVPEPPRFPIIEN 6122
Score = 49.2 bits (112), Expect = 2e-05
Identities = 51/221 (23%), Positives = 81/221 (36%), Gaps = 10/221 (4%)
Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNL 165
R + ++PE V C G PEP W +NG+ L R DG
Sbjct: 5532 RPQIVVKPEDTAQPYNRRAVFTC-EAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKF 5590
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
I++ DAG Y N G+ ++A A L + P + + + +G V +
Sbjct: 5591 TIKEVWDIDAGEYTVEVSNPYGS-DTATANLVVQAPPVIEKDVPNTILPSGDLVRLKIYF 5649
Query: 226 GGD-PL-PDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVILADEGEYSCEAENSVGAVS 282
G P ++ R + P R+ DD L + + + + G Y N G +
Sbjct: 5650 SGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEAT 5709
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
+L V P P ++ N+ T T + RP T
Sbjct: 5710 TGFWLNVTGLPEAPQGPLHIS----NIGPSTATLSWRPPVT 5746
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 32/185 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVWSGA 481
P+PII + + +N R V N G +V+ +SD+G Y A++++GK
Sbjct: 4867 PKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCK-- 4924
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQV 540
++ F V PG PT PI ++ ++TLSW G +I Y V
Sbjct: 4925 ----------LNVF----VLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAITNYVV 4970
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E + T G+ WV + V T V++L Y F VR EN +G+ P
Sbjct: 4971 E---KRTPGGD--------WVTVGHPVGTT-LRVRNLDANTPYEFRVRAENQYGVGEPLE 5018
Query: 601 VSDSV 605
D++
Sbjct: 5019 TDDAI 5023
Score = 48.4 bits (110), Expect = 3e-05
Identities = 24/91 (26%), Positives = 51/91 (56%), Gaps = 4/91 (4%)
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVI 263
G +D+ + G ++ + + G+PLP+ LW + G +GRVK+ + ++++N +
Sbjct: 1801 GIKDLRLKVGETIKYDVPISGEPLPECLWVVN-GKPLKAVGRVKMSSERGKHIMKIENAV 1859
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
AD G+++ +NS G+ ++ +TV P+
Sbjct: 1860 RADSGKFTITLKNSSGSCDSTATVTVVGRPT 1890
Score = 47.6 bits (108), Expect = 5e-05
Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 12/181 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
G+T+ + +P G P P W NG+ L G +M G +++ I++A + D+G++
Sbjct: 1810 GETIKYD-VPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1868
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQ--CRVGGDPLPDVLWR 236
+N++G+ +S AT+ + +P GP D+ V G+++++ GGDPL +
Sbjct: 1869 TLKNSSGSCDST-ATVTVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVE 1927
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS--CEAENSVG---AVSASGYLTVYD 291
V +D + L L ++G Y +A N+ G +SA Y + D
Sbjct: 1928 AQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKD 1987
Query: 292 P 292
P
Sbjct: 1988 P 1988
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 7/100 (7%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVI 263
+ + + G++V ++ ++GG+P+P+V W + G + G +D L + + +
Sbjct: 2099 KSITVKAGATVRWEVKIGGEPIPEVKWFK--GNQQLENGIQLTIDTRKNEHTILCIPSAM 2156
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
+D GEY +NS GA LTV D PS P V+
Sbjct: 2157 RSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVS 2196
Score = 45.2 bits (102), Expect = 3e-04
Identities = 48/204 (23%), Positives = 78/204 (38%), Gaps = 23/204 (11%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNL--- 165
F +P +Q+ GD +++EC P+P + W+ +G L G L GG+L
Sbjct: 7 FTQKPSIQQTPTGD-LLMEC-HLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKA 64
Query: 166 --VIQDARQTDAGRYQCIARNAAGTRESAI--------ATLKIHIKPYLITGPEDVVAQT 215
VI++ D G Y+C ARN G + I P + P +
Sbjct: 65 TLVIKEPNAGDGGAYKCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKDG 124
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGS----LRLDNVILADEG 268
G+ + +C+V P W + G + L D + L + +D G
Sbjct: 125 GALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAG 184
Query: 269 EYSCEAENSVGAVSASGYLTVYDP 292
+Y C N G +A+ L +P
Sbjct: 185 QYRCNIRNDQGETNANLALNFEEP 208
Score = 43.6 bits (98), Expect = 9e-04
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 6/97 (6%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLV 453
P T S+ + A F PEP+I W GE + ++ R V TL
Sbjct: 6863 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6922
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPI 488
+ D KSD G Y C AS+ G+ L V D P+
Sbjct: 6923 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPL 6959
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/182 (24%), Positives = 70/182 (38%), Gaps = 20/182 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGLFFLRATHGRVHS--DAGVYWCE 86
+ C P P I W G L+ +++ P GG + + + D G Y C
Sbjct: 23 MECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKATLVIKEPNAGDGGAYKCT 82
Query: 87 ATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQGDTVVLECLPPRGSPEP 138
A N G + + N L+ A + F +P G +V+EC + + P
Sbjct: 83 ARNQLGESNA-NINLNFAGAGGDEAKSRGPSFVGKPRIIPKDGGALIVMEC-KVKSASTP 140
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGN------LVIQDARQTDAGRYQCIARNAAGTRESA 192
W K+G L G D G+ L I+ +DAG+Y+C RN G +
Sbjct: 141 VAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNAN 200
Query: 193 IA 194
+A
Sbjct: 201 LA 202
Score = 42.7 bits (96), Expect = 0.002
Identities = 117/488 (23%), Positives = 174/488 (35%), Gaps = 59/488 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188
+P RG P P W N + + D R+ D V++ A + AG Y A NA+G+
Sbjct: 2409 VPVRGEPPPKKEWIFNEKPV-DDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGS 2467
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGG 242
+ ++ + + KP GP +V + +V GG P+ ++ A G
Sbjct: 2468 DKHSVEVIVLG-KPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATGR 2526
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+P GR + + N+ E ++ A N G S LT + L+ N
Sbjct: 2527 WVPCGRSETT---KTTVPNLQPGHEYKFRVRAVNKEG---ESDPLTT---NTAILAKNPY 2577
Query: 303 NVESGNVARFTCTATGRPEPTMFWSV--EGNRTI-IFPGMSRDK---YHATAVFDGVTVL 356
V G V + + + W+ +G I F +DK + V G
Sbjct: 2578 EV-PGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQKT 2636
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
K SA N AG+ V + P I S+ T+ + +
Sbjct: 2637 ATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGAT 2696
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASS 471
F P P + W F G+ I + + N+ L + SG YT A++
Sbjct: 2697 LKFIVHIDGEPAPDVTWSFNGKG-IGESKAQIENEPYISRFALPKALRKQSGKYTITATN 2755
Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKI 530
+G DS + NI V S P P PI +V + TL W
Sbjct: 2756 ING---------TDS-VTINI------KVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDD 2799
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G I Y++E T G WV R TH+ V SL G Y F V+
Sbjct: 2800 GGEPIEFYEIE--KMNTKDGI--------WVPCGRS-GDTHFTVDSLNKGDHYKFRVKAV 2848
Query: 591 NSHGLSGP 598
NS G S P
Sbjct: 2849 NSEGPSDP 2856
Score = 42.7 bits (96), Expect = 0.002
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ G P I+ +P D ++ A C A G P P RW + G + + + G+
Sbjct: 5528 SGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGV 5587
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGT 93
+ + T V DAG Y E +N YG+
Sbjct: 5588 Y--KFTIKEVWDIDAGEYTVEVSNPYGS 5613
Score = 41.5 bits (93), Expect = 0.004
Identities = 45/153 (29%), Positives = 66/153 (43%), Gaps = 15/153 (9%)
Query: 178 YQCIARNAAGTRESAIATLKIHI-----KPYLITG--PEDVVAQTGSSVTFQCRVGGDPL 230
++ A NAAG E ++ ++ I +P + G D++A G P
Sbjct: 5104 FRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPA 5163
Query: 231 PDVLWRRSAGGGNMPLGRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P V + + + RVKV D +L ++ L D G Y E ENS G+ SAS L
Sbjct: 5164 PKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQGSDSASIRL 5223
Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D P+ SP + VE ++A CT P
Sbjct: 5224 KVVDKPA---SPQHIRVE--DIAPDCCTLYWMP 5251
Score = 40.3 bits (90), Expect = 0.008
Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 18/147 (12%)
Query: 178 YQCIARNAAGTRE----SAIATLK-IHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDP 229
Y+ +A N AG + SA AT K +H P + G E V + G + P
Sbjct: 4416 YRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRV-KAGEPLVITIPFTASP 4474
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
PD+ W + G PL V+ D + L + + +D G +A N G A+ +T
Sbjct: 4475 QPDISWTKEGG---KPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKIT 4531
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCT 315
V D P +P ++ + V+R TCT
Sbjct: 4532 VIDKPG---APENITYPA--VSRHTCT 4553
Score = 39.9 bits (89), Expect = 0.011
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P P +T S L+W++ + G + I GY VE ++ L N+ R +
Sbjct: 4737 PGAPDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVE---KKKLGDNDWTRCN------ 4787
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
+ V T + VK+L Y F V NS G PS SD V +
Sbjct: 4788 DKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLI 4831
Score = 39.5 bits (88), Expect = 0.014
Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 6/127 (4%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCR-AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G + I D+TV + + AGG+P P I + G + + R+++
Sbjct: 4836 GRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIF-ENERTVVDVNPGE 4894
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESKQSAQGDTVV 126
+ T G SDAG Y ATN YG L+V VL + P Q D +
Sbjct: 4895 IVITTTGSKRSDAGPYKISATNKYG---KDTCKLNVFVLDAPGKPTGPIRATDIQADAMT 4951
Query: 127 LECLPPR 133
L PP+
Sbjct: 4952 LSWRPPK 4958
Score = 38.7 bits (86), Expect = 0.025
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 8/102 (7%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P P ++ TL W + G S I Y VE G W +
Sbjct: 5229 PASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGK--------WEKV 5280
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
+ V +Y V LI Y F VR E +G+S P ++D V
Sbjct: 5281 SSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVV 5322
Score = 38.7 bits (86), Expect = 0.025
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
+++ AP+ + + ++ L C G+P+P I W K G V D +
Sbjct: 6699 EEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDED-RVQVSF 6757
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G+ L + RV DAG Y ATN G
Sbjct: 6758 RSGVCSLEIFNARV-DDAGTYTVTATNDLG 6786
Score = 37.9 bits (84), Expect = 0.043
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 9/86 (10%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR--RNVTNDG----- 450
P T PS Q P + + C P+P IAW G L + R + +T G
Sbjct: 5 PRFTQKPSIQQTPTGDL-LMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYK 63
Query: 451 -TLVLKDLDKSDSGTYTCVASSRHGK 475
TLV+K+ + D G Y C A ++ G+
Sbjct: 64 ATLVIKEPNAGDGGAYKCTARNQLGE 89
Score = 37.5 bits (83), Expect = 0.057
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I P +V V A TC +G P PT W +G+R +I G R K+
Sbjct: 980 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRW-FKGSREVISGG--RFKHITDGKEHT 1036
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
V + + +++ T+ V+ S+ V KL VTSD+
Sbjct: 1037 VALALLKCRSQDEGPYTLTIENVHGTDSADV--KLLVTSDN 1075
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 11/111 (9%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P P P+ +VT S L+W G + I Y VE R+T + NT
Sbjct: 4239 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVVE--KRDTKT--NT----- 4289
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
WV ++ V T V L G Y F V EN+ G S + V D
Sbjct: 4290 -WVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKD 4339
Score = 36.7 bits (81), Expect = 0.10
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-----S 256
P ++ PE+V + C+V G P P W + + + GR K + DG +
Sbjct: 980 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGS-REVISGGRFKHITDGKEHTVA 1038
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L L DEG Y+ EN G SA L V
Sbjct: 1039 LALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 1071
Score = 36.3 bits (80), Expect = 0.13
Identities = 72/307 (23%), Positives = 115/307 (37%), Gaps = 29/307 (9%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
ATL + + W+ G + + + + L R+ D G Y C
Sbjct: 1331 ATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIE-DHGEYKCT-- 1387
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T R + + +F + + + + D V L C + + P + W +NG+
Sbjct: 1388 ----TKDDRTMAQLIVDAKNKFIVALKDTEVIEKDDVTLMC-QTKDTKTPGI-WFRNGKQ 1441
Query: 149 L--LFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYL 204
+ + G +G + L I +A Y+ + AG R S + L+ +P L
Sbjct: 1442 ISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEI---DQAGLRGSCNVTVLEAEKRPIL 1498
Query: 205 ITGPEDVVAQTGS----SVTFQCRVG--GDPLPDVLWRRSAGGGNM-PLGRVKVLDD-GS 256
P+ + A+ G V FQ + GDP +L M L V + DD
Sbjct: 1499 NWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVIIKDDVAE 1558
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV-ARFTCT 315
+ N LAD G+++ E NS G A L V D P P +E+ NV A
Sbjct: 1559 IVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKP----KPPKGPLETKNVTAEGLDL 1614
Query: 316 ATGRPEP 322
G P+P
Sbjct: 1615 VWGTPDP 1621
Score = 36.3 bits (80), Expect = 0.13
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLR 258
+P I P G S F CRV P V W + + +K + D L
Sbjct: 6584 QPRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGLT 6643
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ V D+GEY+ A+NS G +L V
Sbjct: 6644 INRVKGDDKGEYTVRAKNSYGTKEEIVFLNV 6674
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 12/102 (11%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P P + T L W G S I+GYQV+ R+T SG W+
Sbjct: 5330 VPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQY--RDTSSGR--------WIN 5378
Query: 563 IARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+ Q H V L + F + +N+ G S PSP S+
Sbjct: 5379 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSE 5420
Score = 35.1 bits (77), Expect = 0.31
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 11/100 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P + + ++W +K G + I Y VEV +T + W +
Sbjct: 1992 PGKPGRPEITDFDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDT----------KEWKEV 2041
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+RV T+ + L G Y F VR N G PS S+
Sbjct: 2042 -KRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSE 2080
Score = 35.1 bits (77), Expect = 0.31
Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 33/186 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P+ W + R +VTN T + + + D+G Y + + HGK
Sbjct: 3885 PAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYKIIVENEHGK------ 3938
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQV 540
N+ V +PG P P+ + TL+W G + +L Y V
Sbjct: 3939 ----DTAQCNV------TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIV 3988
Query: 541 EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
E SRG W + T V K L+PG Y F V+ N G S P
Sbjct: 3989 EKMD-----------TSRGTWQEVGTFPDCTAKVNK-LVPGKEYAFRVKAVNLQGESKPL 4036
Query: 600 PVSDSV 605
+ +
Sbjct: 4037 EAEEPI 4042
Score = 35.1 bits (77), Expect = 0.31
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P ++ ++TL W++ G + I GY +E RE S W
Sbjct: 5032 PGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIE--KREV--------GSTEWTKA 5081
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
A + T + V L P TY F V N+ G
Sbjct: 5082 AFGNILDTKHRVTGLTPKKTYEFRVAAYNAAG 5113
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/94 (27%), Positives = 32/94 (34%), Gaps = 5/94 (5%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TL 452
P I P N T+ A+ C +P P W+ +I R DG L
Sbjct: 980 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVAL 1039
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
L D G YT + HG LLV S
Sbjct: 1040 ALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTS 1073
Score = 34.7 bits (76), Expect = 0.40
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 1/74 (1%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++ V Q +LN G P+P I W G V SD + G + SD
Sbjct: 3278 EIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRA-LRSD 3336
Query: 80 AGVYWCEATNSYGT 93
G Y +A N GT
Sbjct: 3337 TGTYIIKAENENGT 3350
Score = 34.7 bits (76), Expect = 0.40
Identities = 35/152 (23%), Positives = 61/152 (40%), Gaps = 15/152 (9%)
Query: 178 YQCIARNAAGTRESAIAT-----LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
++ IA NAAG + + T ++KP ++T + + G + + G P P
Sbjct: 4121 FRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPDPT 4180
Query: 233 VLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
W + G L ++D S+ + AD G Y + +N +G A +
Sbjct: 4181 ATW--TVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGEDEAIFEVI 4238
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D PS P +E +V + +C +P
Sbjct: 4239 VQDRPSAPEGP----LEVSDVTKDSCVLNWKP 4266
Score = 33.9 bits (74), Expect = 0.71
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 3/82 (3%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LV 453
PPI+ +QT I V C II WY +G + + + + +G+ L
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 454 LKDLDKSDSGTYTCVASSRHGK 475
+ L + SG Y C A +G+
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGE 458
Score = 33.5 bits (73), Expect = 0.93
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 13/114 (11%)
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNVESGNVAR 311
+L ++N + D G+Y+CEA V LTV +PP +N PN+ + A
Sbjct: 1185 TLIINNPEVDDTGKYTCEA----NGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAV 1240
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
TC P + W G++ I G R AV G LTI + +++D
Sbjct: 1241 LTC-KVNTPRAPLVW-YRGSKA-IQEGDPRFIIEKDAV--GRCTLTIKEVEEDD 1289
Score = 32.7 bits (71), Expect = 1.6
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 12/100 (12%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P PP P+ T NVT + L W + + + Y +E+ +E SGN
Sbjct: 1591 VKDKPKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEM--QEGRSGN------- 1641
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
W + T + VK L Y F V+ N GLS P
Sbjct: 1642 -WAKVGE-TKGTDFKVKDLKEHGEYKFRVKALNECGLSDP 1679
Score = 32.3 bits (70), Expect = 2.2
Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 1/83 (1%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV + GG P P ++W+KG + + +I + + SD
Sbjct: 2101 ITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDV 2160
Query: 81 GVYWCEATNSYGTARSRNATLHV 103
G Y NS+G A A L V
Sbjct: 2161 GEYRLTVKNSHG-ADEEKANLTV 2182
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 11/101 (10%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P KP + + + W+ G + + GY VE + S W
Sbjct: 4050 VPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVE----------KKEKGSAIWTE 4099
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
A + T + +L PG+ Y F V N+ G S PS +D
Sbjct: 4100 -AGKTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTD 4139
Score = 32.3 bits (70), Expect = 2.2
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
+ D P P +E+ + + L W PP+ +G N VV D N + V ++
Sbjct: 4239 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPK---DDGGAEISNYVVEKRDTKTN-TWVPVS 4294
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
V TS+ + LT G Y ++ AE G
Sbjct: 4295 AFV-TGTSITVPKLTEGHEYEFRVMAENTFG 4324
Score = 31.9 bits (69), Expect = 2.9
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 12/94 (12%)
Query: 504 PGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
P P P+ +V + ++ LSW + G I Y+VE +T +G WV
Sbjct: 2186 PSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVE--KLDTATGR--------WVP 2235
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
A +V T + L G TY F V+ N G S
Sbjct: 2236 CA-KVKDTKAHIDGLKKGQTYQFRVKAVNKEGAS 2268
Score = 31.1 bits (67), Expect = 5.0
Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 11/111 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PGPP ++ T++W + G S I GY VE+ RE S W V
Sbjct: 5431 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEI--RE--------YGSTLWTVA 5480
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ V + + V L Y F V N+ G PS S + + + S
Sbjct: 5481 SDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5531
Score = 30.3 bits (65), Expect = 8.7
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 11/123 (8%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD---DGSLRLD 260
+ G D+ + G+ + G+P P W+ A + G R V + ++ +
Sbjct: 3861 LAGLLDLRIKAGTPIKLDIAFEGEPAPVAKWK--ANDATIDTGARADVTNTPTSSAIHIF 3918
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ + D G Y EN G +A +TV D P P ++ + + CT +P
Sbjct: 3919 SAVRGDTGVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKID----EIHKEGCTLNWKP 3974
Query: 321 EPT 323
PT
Sbjct: 3975 -PT 3976
>Z73897-4|CAA98064.2| 6839|Caenorhabditis elegans Hypothetical protein
ZK617.1a protein.
Length = 6839
Score = 76.6 bits (180), Expect = 1e-13
Identities = 86/324 (26%), Positives = 130/324 (40%), Gaps = 44/324 (13%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + +N E G F C +G P P W +G + ++ KY T + G
Sbjct: 5604 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRW-FKGCKELV----DTSKY--TLINKG 5656
Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLP 410
VL IND +D+ + C A N +G+ R L + T PP G Q
Sbjct: 5657 DKQVLIINDLTSDDA-DEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGE 5715
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTC 467
+ + P A P+ W +GE + N + ++T D TL + + + D G Y
Sbjct: 5716 TIELKI-PYKAY--PQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRV 5772
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
V + G SG + V V+ +P PP PI N+ D +V LSW
Sbjct: 5773 VVENSVGSD--SGTVNVT--------------VADVPEPPRFPIIENILDEAVILSWKPP 5816
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
G S + Y +E RE + G+ +P + T+ ++ L G Y F +
Sbjct: 5817 ALDGGSLVTNYTIE--KREAMGGSWSP---------CAKSRYTYTTIEGLRAGKQYEFRI 5865
Query: 588 RTENSHGLSGP-SPVSDSVTVGDD 610
EN HG S P P + + GD+
Sbjct: 5866 IAENKHGQSKPCEPTAPVLIPGDE 5889
Score = 73.7 bits (173), Expect = 7e-13
Identities = 52/192 (27%), Positives = 88/192 (45%), Gaps = 12/192 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SGE P I+ D+ + T C GSP P RW+KG +V + +++ G
Sbjct: 5600 SGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQ 5659
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDT 124
L + DA Y C ATNS GT RS A L + F + P+ ++ +G+T
Sbjct: 5660 VL-IINDLTSDDADEYTCRATNSSGT-RSTRANLRIKTKPRVF-IPPKYHGGYEAQKGET 5716
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCI 181
+ L+ +P + P+ W K+G+ + + +S+ + L I +A + D G Y+ +
Sbjct: 5717 IELK-IPYKAYPQGEARWTKDGEKI--ENNSKFSITTDDKFATLRISNASREDYGEYRVV 5773
Query: 182 ARNAAGTRESAI 193
N+ G+ +
Sbjct: 5774 VENSVGSDSGTV 5785
Score = 72.9 bits (171), Expect = 1e-12
Identities = 121/493 (24%), Positives = 190/493 (38%), Gaps = 72/493 (14%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G P P+V W NG+ + G+S+ + + + A + +G+Y A N GT +
Sbjct: 2386 GEPAPDVTWSFNGKGI---GESKAQIENEPYISRFALPKALRKQSGKYTITATNINGT-D 2441
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGGNM 244
S +K+ KP GP +V T + GG+P+ ++ + G +
Sbjct: 2442 SVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWV 2501
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT------VYDPPSINLS 298
P GR D +D++ D ++ +A NS G T +D P
Sbjct: 2502 PCGRS---GDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGR 2558
Query: 299 PNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH----ATAVFDGV 353
P + +S +V ++ + P + +E R KY A V G
Sbjct: 2559 PEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIE----------KRTKYGRWEPAITVPGGQ 2608
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPI 411
T T+ D N+ V AVN G S K + + P I + N T+
Sbjct: 2609 TTATVPDLTPNEEYEFRVV-AVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKA 2667
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTC 467
F P P + W++ I+N R N LV+K +++ DSGT+T
Sbjct: 2668 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTI 2727
Query: 468 VASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
A + +G+ + + ++D P +PN DVS + G VTL+W
Sbjct: 2728 KAVNANGEDEATVKINVIDKPTSPN----GPLDVSDVHG------------DHVTLNWRA 2771
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV-HQTHYVVKSLIPGITYMF 585
+ G I Y +E + +T SG WV A+ +T VV LIPG Y F
Sbjct: 2772 PDDDGGIPIENYVIEKY--DTASGR--------WVPAAKVAGDKTTAVVDGLIPGHEYKF 2821
Query: 586 IVRTENSHGLSGP 598
V N+ G S P
Sbjct: 2822 RVAAVNAEGESDP 2834
Score = 72.1 bits (169), Expect = 2e-12
Identities = 118/494 (23%), Positives = 170/494 (34%), Gaps = 39/494 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I +P V Q A CR S P + W+K + G + L
Sbjct: 6266 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGL-- 6323
Query: 72 THGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLEC 129
T RV D G Y A NSYGT + L+V E + EP E + A V E
Sbjct: 6324 TINRVKGDDKGEYTVRAKNSYGT-KEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVEEF 6382
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ---DARQTDAGRYQCIARNAA 186
R +P + + L N I+ D D R Q R+
Sbjct: 6383 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGV 6442
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+ E A + Y +T D+ V GG+P+P V R P
Sbjct: 6443 CSLEIFNARVD-DAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRVSSFR-------PR 6494
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVN 303
L G+ + AD S + S SA+ L + PS +
Sbjct: 6495 RAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSFTAQLSDSE 6554
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
E G A F+ +G+PEP + W G R S ++ A+ V G L I+D K
Sbjct: 6555 TEVGGSAEFSAAVSGQPEPLIEWLHNGERI----SESDSRFRASYV-AGKATLRISDAKK 6609
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD----------RPPPIITNGPSNQTLPIKS 413
+D +C A N AG R LTV D +T + +
Sbjct: 6610 SD-EGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGE 6668
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
F TPE ++ W G+ L + +++ DG + + D SD+G Y
Sbjct: 6669 SVTFEARVQGTPEEVL-WMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVR 6727
Query: 471 SRHGKYVWSGALLV 484
S+ V +L+V
Sbjct: 6728 SKGTNLVSVASLVV 6741
Score = 68.1 bits (159), Expect = 4e-11
Identities = 57/180 (31%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178
G V EC GSP P W K + L+ S+ L++ G+ L+I D DA Y
Sbjct: 5618 GRCVTFEC-EISGSPRPEYRWFKGCKELV--DTSKYTLINKGDKQVLIINDLTSDDADEY 5674
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLW 235
C A N++GTR S A L+I KP + P+ AQ G ++ + P + W
Sbjct: 5675 TCRATNSSGTR-STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARW 5733
Query: 236 RRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ DD +LR+ N D GEY ENSVG+ S + +TV D P
Sbjct: 5734 TKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVP 5793
Score = 67.3 bits (157), Expect = 6e-11
Identities = 63/206 (30%), Positives = 93/206 (45%), Gaps = 32/206 (15%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G PEP + W NG+ + + DSR ++ L I DA+++D G+Y C A N+AG +E
Sbjct: 6569 GQPEPLIEWLHNGERIS-ESDSRFRASYVAGKATLRISDAKKSDEGQYLCRASNSAG-QE 6626
Query: 191 SAIATLKIHIKPYLITGPE---------------DVVAQTGSSVTFQCRVGGDPLPDVLW 235
ATL + L+ G + G SVTF+ RV G P +VLW
Sbjct: 6627 QTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGESVTFEARVQGTP-EEVLW 6685
Query: 236 RRSAGGGNMPLG-RVKVLDDG---SLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTV- 289
R+ G + G + + DG S +++ +D G Y E + VS + + V
Sbjct: 6686 MRN--GQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVRSKGTNLVSVASLVVVG 6743
Query: 290 --YDPPSINLSPNSVNVESGNVARFT 313
DPP L P+SV+ G FT
Sbjct: 6744 EKADPPVTRL-PSSVSAPLGGSTAFT 6768
Score = 66.1 bits (154), Expect = 1e-10
Identities = 123/504 (24%), Positives = 191/504 (37%), Gaps = 63/504 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186
+P G P P V W + +G R+ L + LV++ + D+G + A NA
Sbjct: 2675 VPVSGEPAPTVTWHWPDNREIRNG-GRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNAN 2733
Query: 187 GTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRR--S 238
G E AT+KI++ KP GP DV G VT R GG P+ + + + +
Sbjct: 2734 GEDE---ATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDT 2790
Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDP--- 292
A G +P +V D + +D +I E ++ A N+ G + G DP
Sbjct: 2791 ASGRWVPAAKVAG-DKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDK 2849
Query: 293 PSINLSPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P +P + + +V + A P + VE F D H A
Sbjct: 2850 PGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDE--FSPFWNDVAHVPAGQT 2907
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
TV + + K + R A N AG + + PP+I S Q + +
Sbjct: 2908 NATVGNLKEGSKYEFR----IRAKNKAGLGDPSDSASAVAKARNVPPVIDRN-SIQEIKV 2962
Query: 412 KSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRNVTN-DG--TLVLKDLDKSDSGTYT 466
K+ F + P P I W FEG + + R + N DG +K +SD+GTY
Sbjct: 2963 KAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 3022
Query: 467 CVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
A + +G + V D P +P GP +T N+ L+W
Sbjct: 3023 IKAENENGTDTAEVKVTVLDHPSSPR-------------GP--LDVT-NIVKDGCDLAWK 3066
Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585
+ G + I Y +E ++ +G W T++ V L G Y F
Sbjct: 3067 EPEDDGGAEISHYVIE--KQDAATGR--------WTACGES-KDTNFHVDDLTQGHEYKF 3115
Query: 586 IVRTENSHGLSGPSPVSDSVTVGD 609
V+ N HG S P +++ D
Sbjct: 3116 RVKAVNRHGDSDPLEAREAIIAKD 3139
Score = 64.1 bits (149), Expect = 6e-10
Identities = 80/312 (25%), Positives = 116/312 (37%), Gaps = 45/312 (14%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + P A FTC A GRPEPT W G P SR ++ A+ DG
Sbjct: 5214 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRE---LPESSRYRFEAS---DG 5267
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
V TI + D+ V N GS L V + PP+I N LP
Sbjct: 5268 VYKFTIKEVWDIDAGEYTV-EVSNPYGSDTATANLVVQA-----PPVIEKDVPNTILPSG 5321
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEA-----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
+ YF G A L+ N + T+ + + D T
Sbjct: 5322 DLVRLKI------------YFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPA 5369
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQ 526
++ G+Y ++ + + F+ +V+ LP P P+ N+ ++ TLSW
Sbjct: 5370 LSVREAGRYEYT---VSNDSGEATTGFW--LNVTGLPEAPQGPLHISNIGPSTATLSWRP 5424
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
G S I Y VE + LS + WV + V +Y+V L Y F
Sbjct: 5425 PVTDGGSKITSYVVE---KRDLSKDE-------WVTVTSNVKDMNYIVTGLFENHEYEFR 5474
Query: 587 VRTENSHGLSGP 598
V +N +G+ P
Sbjct: 5475 VSAQNENGIGAP 5486
Score = 60.9 bits (141), Expect = 5e-09
Identities = 84/305 (27%), Positives = 118/305 (38%), Gaps = 30/305 (9%)
Query: 2 SDDYVT--SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHR 58
+DD T + E P Q D A + G P P I W G + SD+
Sbjct: 6532 ADDLKTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRF 6591
Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV------------AVL 106
G LR + + SD G Y C A+NS G ++R ATL V +
Sbjct: 6592 RASYVAGKATLRISDAK-KSDEGQYLCRASNSAGQEQTR-ATLTVKGDQPLLNGHAGQAV 6649
Query: 107 REEFRLEPE--SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
E R+ + G++V E +G+PE V W +NGQ L +GD DG
Sbjct: 6650 ESELRVTKHLGGEIVNNGESVTFEA-RVQGTPE-EVLWMRNGQELT-NGDKTSISQDGET 6706
Query: 165 L--VIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGSSV 219
L I A +DAG YQ R + GT ++A+L + P + P V A G S
Sbjct: 6707 LSFTINSADASDAGHYQLEVR-SKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGST 6765
Query: 220 TFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
F V W R + N + VK + L + NV D+G Y +
Sbjct: 6766 AFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKE 6825
Query: 278 VGAVS 282
A++
Sbjct: 6826 KKAIA 6830
Score = 56.0 bits (129), Expect = 2e-07
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 1/116 (0%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SG AP I+E P +VTV ++ A L C+ GSP+P RW+KG V+S + G
Sbjct: 657 SGSAPKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEH 716
Query: 68 FLRATHGRVHS-DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQG 122
+ + S D G Y N +GT + L + +FR + ++S G
Sbjct: 717 TVALALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTSDNGLDFRAMLKHRESQAG 772
Score = 56.0 bits (129), Expect = 2e-07
Identities = 83/317 (26%), Positives = 122/317 (38%), Gaps = 41/317 (12%)
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
++L V++G T T P+P + W+ EG + + D T
Sbjct: 4130 LDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLA----------GVETTDSQT 4179
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
L I T ++DS + AVN G + K+TV D+P P N T P S
Sbjct: 4180 KLVIPSTRRSDS-GPVKIKAVNPYGEAEANIKITVI---DKP-----GAPENITYPAVSR 4230
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
CT A +G A I ++ G+ + + SGT V HG
Sbjct: 4231 HT--CTLNWD-----APKDDGGAEIAGYKIEYQEVGSQIWDKVPGLISGTAYTVRGLEHG 4283
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVT--DTS-VTLSWSQNNKI 530
+ + + ++ + + + V P PP P T +T DT+ V+L+W+
Sbjct: 4284 QQ-YRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQVSLAWNPPRDD 4342
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
G S ILGY VE F + R W + V T +V L TY F VR
Sbjct: 4343 GGSPILGYVVERFEK---------RGGGDWAPVKMPMVKGTECIVPGLHENETYQFRVRA 4393
Query: 590 ENSHGLSGPSPVSDSVT 606
N+ G PS S+ VT
Sbjct: 4394 VNAAGHGEPSNGSEPVT 4410
Score = 54.0 bits (124), Expect = 6e-07
Identities = 114/486 (23%), Positives = 176/486 (36%), Gaps = 52/486 (10%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+P G P P + W G + D +++ DG ++ A ++D G Y A N GT
Sbjct: 2972 IPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENGT 3031
Query: 189 RESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGN 243
++A + + P GP DV + + G + ++ GG + V+ ++ A G
Sbjct: 3032 -DTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISHYVIEKQDAATGR 3090
Query: 244 MPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSP 299
G K D + +D++ E ++ +A N G + A + DP P
Sbjct: 3091 WTACGESK---DTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEAREAIIAKDPFDRADKP 3147
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ + + T P +EG + S D A V G T++
Sbjct: 3148 GTPEIVDWDKDHADLKWTP-PADDGGAPIEGY-LVEMRTPSGDWVPAVTVGAGELTATVD 3205
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+ V A+N AG S + V P I + Q + F
Sbjct: 3206 GLKPGQTYQFRV-KALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNF 3264
Query: 418 PCTAICTPEPIIAWYFEGEALIQN---HRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRH 473
P P I W+ G L H N T++ T L K ++DSG Y VA++
Sbjct: 3265 DVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNES 3324
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGS 532
GK + ++ NI +PG P P+ H ++T SV L W + G
Sbjct: 3325 GK--------DEHEVDVNI--------LDIPGAPEGPLRHKDITKESVVLKWDEPLDDGG 3368
Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
S I Y VE ++ G WV T V L G Y F V+ N
Sbjct: 3369 SPITNYVVE---KQEDGGR--------WVPCG-ETSDTSLKVNKLSEGHEYKFRVKAVNR 3416
Query: 593 HGLSGP 598
G S P
Sbjct: 3417 QGTSAP 3422
Score = 51.6 bits (118), Expect = 3e-06
Identities = 110/454 (24%), Positives = 173/454 (38%), Gaps = 65/454 (14%)
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI------KPYLITGPEDVVAQTGSSVT 220
+ R+ + ++ +A NAAG ++ + I I +P ++ PED
Sbjct: 5173 VDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAV 5232
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKV-LDDGSLR--LDNVILADEGEYSCEAEN 276
F C G P P W R+ G +P R + DG + + V D GEY+ E N
Sbjct: 5233 FTCEAVGRPEPTARWLRN--GRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSN 5290
Query: 277 SVGAVSASGYLTVYDPPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
G+ +A+ L V PP I PN++ + SG++ R +G + +++
Sbjct: 5291 PYGSDTATANLVVQAPPVIEKDVPNTI-LPSGDLVRLKIYFSG--------TAPFRHSLV 5341
Query: 336 FPGMSRDKYHAT---AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
D H T FD ++TI ++ + N +G + L VT
Sbjct: 5342 LNREEIDMDHPTIRIVEFDDHILITIPALSVREA-GRYEYTVSNDSGEATTGFWLNVTGL 5400
Query: 393 DDRP--PPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN- 448
+ P P I+N GPS TL + P T I ++ E L ++ VT+
Sbjct: 5401 PEAPQGPLHISNIGPSTATLSWRP----PVTD--GGSKITSYVVEKRDLSKDEWVTVTSN 5454
Query: 449 --DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPG 505
D ++ L ++ + A + +G GA LV + PI + F
Sbjct: 5455 VKDMNYIVTGLFENHEYEFRVSAQNENG----IGAPLVSEHPIIARLPF----------D 5500
Query: 506 PPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
PPT P+ + VTLSW + G + GY VE E +N
Sbjct: 5501 PPTSPLNLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPS---- 5556
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
+Y V +LI G Y + V N GLS
Sbjct: 5557 -----PPNNYNVPNLIDGRKYRYRVFAVNDAGLS 5585
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/209 (22%), Positives = 82/209 (39%), Gaps = 17/209 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P +++ D+ + G VTF+C + G P P+ W + + + +++ G L
Sbjct: 5604 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGC-KELVDTSKYTLINKGDKQVLI 5662
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCT 315
++++ D EY+C A NS G S L + P + + P + G
Sbjct: 5663 INDLTSDDADEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIP 5722
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
P+ W+ +G + + K+ T D L I++ + D V
Sbjct: 5723 YKAYPQGEARWTKDGEKI-----ENNSKFSIT-TDDKFATLRISNASREDYGEYRVV-VE 5775
Query: 376 NYAGSSFVRGKLTVTSDDDRPP--PIITN 402
N GS +TV +D PP PII N
Sbjct: 5776 NSVGSDSGTVNVTV-ADVPEPPRFPIIEN 5803
Score = 49.2 bits (112), Expect = 2e-05
Identities = 51/221 (23%), Positives = 81/221 (36%), Gaps = 10/221 (4%)
Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNL 165
R + ++PE V C G PEP W +NG+ L R DG
Sbjct: 5213 RPQIVVKPEDTAQPYNRRAVFTC-EAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKF 5271
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
I++ DAG Y N G+ ++A A L + P + + + +G V +
Sbjct: 5272 TIKEVWDIDAGEYTVEVSNPYGS-DTATANLVVQAPPVIEKDVPNTILPSGDLVRLKIYF 5330
Query: 226 GGD-PL-PDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVILADEGEYSCEAENSVGAVS 282
G P ++ R + P R+ DD L + + + + G Y N G +
Sbjct: 5331 SGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEAT 5390
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
+L V P P ++ N+ T T + RP T
Sbjct: 5391 TGFWLNVTGLPEAPQGPLHIS----NIGPSTATLSWRPPVT 5427
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 32/185 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVWSGA 481
P+PII + + +N R V N G +V+ +SD+G Y A++++GK
Sbjct: 4548 PKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCK-- 4605
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQV 540
++ F V PG PT PI ++ ++TLSW G +I Y V
Sbjct: 4606 ----------LNVF----VLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAITNYVV 4651
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E + T G+ WV + V T V++L Y F VR EN +G+ P
Sbjct: 4652 E---KRTPGGD--------WVTVGHPVGTT-LRVRNLDANTPYEFRVRAENQYGVGEPLE 4699
Query: 601 VSDSV 605
D++
Sbjct: 4700 TDDAI 4704
Score = 48.4 bits (110), Expect = 3e-05
Identities = 24/91 (26%), Positives = 51/91 (56%), Gaps = 4/91 (4%)
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVI 263
G +D+ + G ++ + + G+PLP+ LW + G +GRVK+ + ++++N +
Sbjct: 1482 GIKDLRLKVGETIKYDVPISGEPLPECLWVVN-GKPLKAVGRVKMSSERGKHIMKIENAV 1540
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
AD G+++ +NS G+ ++ +TV P+
Sbjct: 1541 RADSGKFTITLKNSSGSCDSTATVTVVGRPT 1571
Score = 47.6 bits (108), Expect = 5e-05
Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 12/181 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
G+T+ + +P G P P W NG+ L G +M G +++ I++A + D+G++
Sbjct: 1491 GETIKYD-VPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 1549
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQ--CRVGGDPLPDVLWR 236
+N++G+ +S AT+ + +P GP D+ V G+++++ GGDPL +
Sbjct: 1550 TLKNSSGSCDST-ATVTVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVE 1608
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS--CEAENSVG---AVSASGYLTVYD 291
V +D + L L ++G Y +A N+ G +SA Y + D
Sbjct: 1609 AQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKD 1668
Query: 292 P 292
P
Sbjct: 1669 P 1669
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 7/100 (7%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVI 263
+ + + G++V ++ ++GG+P+P+V W + G + G +D L + + +
Sbjct: 1780 KSITVKAGATVRWEVKIGGEPIPEVKWFK--GNQQLENGIQLTIDTRKNEHTILCIPSAM 1837
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
+D GEY +NS GA LTV D PS P V+
Sbjct: 1838 RSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVS 1877
Score = 45.2 bits (102), Expect = 3e-04
Identities = 48/204 (23%), Positives = 78/204 (38%), Gaps = 23/204 (11%)
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNL--- 165
F +P +Q+ GD +++EC P+P + W+ +G L G L GG+L
Sbjct: 7 FTQKPSIQQTPTGD-LLMEC-HLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKA 64
Query: 166 --VIQDARQTDAGRYQCIARNAAGTRESAI--------ATLKIHIKPYLITGPEDVVAQT 215
VI++ D G Y+C ARN G + I P + P +
Sbjct: 65 TLVIKEPNAGDGGAYKCTARNQLGESNANINLNFAGAGGDEAKSRGPSFVGKPRIIPKDG 124
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSA---GGGNMPLGRVKVLDDGS----LRLDNVILADEG 268
G+ + +C+V P W + G + L D + L + +D G
Sbjct: 125 GALIVMECKVKSASTPVAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAG 184
Query: 269 EYSCEAENSVGAVSASGYLTVYDP 292
+Y C N G +A+ L +P
Sbjct: 185 QYRCNIRNDQGETNANLALNFEEP 208
Score = 43.6 bits (98), Expect = 9e-04
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 6/97 (6%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLV 453
P T S+ + A F PEP+I W GE + ++ R V TL
Sbjct: 6544 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 6603
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPI 488
+ D KSD G Y C AS+ G+ L V D P+
Sbjct: 6604 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPL 6640
Score = 43.2 bits (97), Expect = 0.001
Identities = 45/182 (24%), Positives = 70/182 (38%), Gaps = 20/182 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTH--RSILPAGGLFFLRATHGRVHS--DAGVYWCE 86
+ C P P I W G L+ +++ P GG + + + D G Y C
Sbjct: 23 MECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYKATLVIKEPNAGDGGAYKCT 82
Query: 87 ATNSYGTARSRNATLHVAVLREE--------FRLEPESKQSAQGDTVVLECLPPRGSPEP 138
A N G + + N L+ A + F +P G +V+EC + + P
Sbjct: 83 ARNQLGESNA-NINLNFAGAGGDEAKSRGPSFVGKPRIIPKDGGALIVMEC-KVKSASTP 140
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGN------LVIQDARQTDAGRYQCIARNAAGTRESA 192
W K+G L G D G+ L I+ +DAG+Y+C RN G +
Sbjct: 141 VAKWMKDGVPLSMGGLYHAIFSDLGDQTYLCQLEIRGPSSSDAGQYRCNIRNDQGETNAN 200
Query: 193 IA 194
+A
Sbjct: 201 LA 202
Score = 42.7 bits (96), Expect = 0.002
Identities = 117/488 (23%), Positives = 174/488 (35%), Gaps = 59/488 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188
+P RG P P W N + + D R+ D V++ A + AG Y A NA+G+
Sbjct: 2090 VPVRGEPPPKKEWIFNEKPV-DDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGS 2148
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGG 242
+ ++ + + KP GP +V + +V GG P+ ++ A G
Sbjct: 2149 DKHSVEVIVLG-KPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATGR 2207
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+P GR + + N+ E ++ A N G S LT + L+ N
Sbjct: 2208 WVPCGRSETT---KTTVPNLQPGHEYKFRVRAVNKEG---ESDPLTT---NTAILAKNPY 2258
Query: 303 NVESGNVARFTCTATGRPEPTMFWSV--EGNRTI-IFPGMSRDK---YHATAVFDGVTVL 356
V G V + + + W+ +G I F +DK + V G
Sbjct: 2259 EV-PGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQKT 2317
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
K SA N AG+ V + P I S+ T+ + +
Sbjct: 2318 ATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGAT 2377
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASS 471
F P P + W F G+ I + + N+ L + SG YT A++
Sbjct: 2378 LKFIVHIDGEPAPDVTWSFNGKG-IGESKAQIENEPYISRFALPKALRKQSGKYTITATN 2436
Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKI 530
+G DS + NI V S P P PI +V + TL W
Sbjct: 2437 ING---------TDS-VTINI------KVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDD 2480
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G I Y++E T G WV R TH+ V SL G Y F V+
Sbjct: 2481 GGEPIEFYEIE--KMNTKDGI--------WVPCGRS-GDTHFTVDSLNKGDHYKFRVKAV 2529
Query: 591 NSHGLSGP 598
NS G S P
Sbjct: 2530 NSEGPSDP 2537
Score = 42.7 bits (96), Expect = 0.002
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ G P I+ +P D ++ A C A G P P RW + G + + + G+
Sbjct: 5209 SGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGV 5268
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGT 93
+ + T V DAG Y E +N YG+
Sbjct: 5269 Y--KFTIKEVWDIDAGEYTVEVSNPYGS 5294
Score = 41.5 bits (93), Expect = 0.004
Identities = 45/153 (29%), Positives = 66/153 (43%), Gaps = 15/153 (9%)
Query: 178 YQCIARNAAGTRESAIATLKIHI-----KPYLITG--PEDVVAQTGSSVTFQCRVGGDPL 230
++ A NAAG E ++ ++ I +P + G D++A G P
Sbjct: 4785 FRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPA 4844
Query: 231 PDVLWRRSAGGGNMPLGRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P V + + + RVKV D +L ++ L D G Y E ENS G+ SAS L
Sbjct: 4845 PKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQGSDSASIRL 4904
Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D P+ SP + VE ++A CT P
Sbjct: 4905 KVVDKPA---SPQHIRVE--DIAPDCCTLYWMP 4932
Score = 40.3 bits (90), Expect = 0.008
Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 18/147 (12%)
Query: 178 YQCIARNAAGTRE----SAIATLK-IHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDP 229
Y+ +A N AG + SA AT K +H P + G E V + G + P
Sbjct: 4097 YRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRV-KAGEPLVITIPFTASP 4155
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
PD+ W + G PL V+ D + L + + +D G +A N G A+ +T
Sbjct: 4156 QPDISWTKEGG---KPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKIT 4212
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCT 315
V D P +P ++ + V+R TCT
Sbjct: 4213 VIDKPG---APENITYPA--VSRHTCT 4234
Score = 39.9 bits (89), Expect = 0.011
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P P +T S L+W++ + G + I GY VE ++ L N+ R +
Sbjct: 4418 PGAPDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVE---KKKLGDNDWTRCN------ 4468
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
+ V T + VK+L Y F V NS G PS SD V +
Sbjct: 4469 DKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLI 4512
Score = 39.5 bits (88), Expect = 0.014
Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 6/127 (4%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCR-AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G + I D+TV + + AGG+P P I + G + + R+++
Sbjct: 4517 GRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIF-ENERTVVDVNPGE 4575
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESKQSAQGDTVV 126
+ T G SDAG Y ATN YG L+V VL + P Q D +
Sbjct: 4576 IVITTTGSKRSDAGPYKISATNKYG---KDTCKLNVFVLDAPGKPTGPIRATDIQADAMT 4632
Query: 127 LECLPPR 133
L PP+
Sbjct: 4633 LSWRPPK 4639
Score = 38.7 bits (86), Expect = 0.025
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 8/102 (7%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P P ++ TL W + G S I Y VE G W +
Sbjct: 4910 PASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGK--------WEKV 4961
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
+ V +Y V LI Y F VR E +G+S P ++D V
Sbjct: 4962 SSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVV 5003
Score = 38.7 bits (86), Expect = 0.025
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
+++ AP+ + + ++ L C G+P+P I W K G V D +
Sbjct: 6380 EEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDED-RVQVSF 6438
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G+ L + RV DAG Y ATN G
Sbjct: 6439 RSGVCSLEIFNARV-DDAGTYTVTATNDLG 6467
Score = 37.9 bits (84), Expect = 0.043
Identities = 27/86 (31%), Positives = 39/86 (45%), Gaps = 9/86 (10%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR--RNVTNDG----- 450
P T PS Q P + + C P+P IAW G L + R + +T G
Sbjct: 5 PRFTQKPSIQQTPTGDL-LMECHLEADPQPTIAWQHSGNLLEPSGRVVQTLTPLGGSLYK 63
Query: 451 -TLVLKDLDKSDSGTYTCVASSRHGK 475
TLV+K+ + D G Y C A ++ G+
Sbjct: 64 ATLVIKEPNAGDGGAYKCTARNQLGE 89
Score = 37.5 bits (83), Expect = 0.057
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 5/101 (4%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I P +V V A TC +G P PT W +G+R +I G R K+
Sbjct: 661 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRW-FKGSREVISGG--RFKHITDGKEHT 717
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
V + + +++ T+ V+ S+ V KL VTSD+
Sbjct: 718 VALALLKCRSQDEGPYTLTIENVHGTDSADV--KLLVTSDN 756
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 11/111 (9%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P P P+ +VT S L+W G + I Y VE R+T + NT
Sbjct: 3920 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVVE--KRDTKT--NT----- 3970
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
WV ++ V T V L G Y F V EN+ G S + V D
Sbjct: 3971 -WVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKD 4020
Score = 36.7 bits (81), Expect = 0.10
Identities = 28/93 (30%), Positives = 39/93 (41%), Gaps = 6/93 (6%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG-----S 256
P ++ PE+V + C+V G P P W + + + GR K + DG +
Sbjct: 661 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGS-REVISGGRFKHITDGKEHTVA 719
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
L L DEG Y+ EN G SA L V
Sbjct: 720 LALLKCRSQDEGPYTLTIENVHGTDSADVKLLV 752
Score = 36.3 bits (80), Expect = 0.13
Identities = 72/307 (23%), Positives = 115/307 (37%), Gaps = 29/307 (9%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
ATL + + W+ G + + + + L R+ D G Y C
Sbjct: 1012 ATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIE-DHGEYKCT-- 1068
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T R + + +F + + + + D V L C + + P + W +NG+
Sbjct: 1069 ----TKDDRTMAQLIVDAKNKFIVALKDTEVIEKDDVTLMC-QTKDTKTPGI-WFRNGKQ 1122
Query: 149 L--LFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYL 204
+ + G +G + L I +A Y+ + AG R S + L+ +P L
Sbjct: 1123 ISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEI---DQAGLRGSCNVTVLEAEKRPIL 1179
Query: 205 ITGPEDVVAQTGS----SVTFQCRVG--GDPLPDVLWRRSAGGGNM-PLGRVKVLDD-GS 256
P+ + A+ G V FQ + GDP +L M L V + DD
Sbjct: 1180 NWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVIIKDDVAE 1239
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV-ARFTCT 315
+ N LAD G+++ E NS G A L V D P P +E+ NV A
Sbjct: 1240 IVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKP----KPPKGPLETKNVTAEGLDL 1295
Query: 316 ATGRPEP 322
G P+P
Sbjct: 1296 VWGTPDP 1302
Score = 36.3 bits (80), Expect = 0.13
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLR 258
+P I P G S F CRV P V W + + +K + D L
Sbjct: 6265 QPRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGLT 6324
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ V D+GEY+ A+NS G +L V
Sbjct: 6325 INRVKGDDKGEYTVRAKNSYGTKEEIVFLNV 6355
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 12/102 (11%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P P + T L W G S I+GYQV+ R+T SG W+
Sbjct: 5011 VPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQY--RDTSSGR--------WIN 5059
Query: 563 IARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+ Q H V L + F + +N+ G S PSP S+
Sbjct: 5060 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSE 5101
Score = 35.1 bits (77), Expect = 0.31
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 11/100 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P + + ++W +K G + I Y VEV +T + W +
Sbjct: 1673 PGKPGRPEITDFDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDT----------KEWKEV 1722
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+RV T+ + L G Y F VR N G PS S+
Sbjct: 1723 -KRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSE 1761
Score = 35.1 bits (77), Expect = 0.31
Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 33/186 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P+ W + R +VTN T + + + D+G Y + + HGK
Sbjct: 3566 PAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYKIIVENEHGK------ 3619
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQV 540
N+ V +PG P P+ + TL+W G + +L Y V
Sbjct: 3620 ----DTAQCNV------TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIV 3669
Query: 541 EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
E SRG W + T V K L+PG Y F V+ N G S P
Sbjct: 3670 EKMD-----------TSRGTWQEVGTFPDCTAKVNK-LVPGKEYAFRVKAVNLQGESKPL 3717
Query: 600 PVSDSV 605
+ +
Sbjct: 3718 EAEEPI 3723
Score = 35.1 bits (77), Expect = 0.31
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P ++ ++TL W++ G + I GY +E RE S W
Sbjct: 4713 PGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIE--KREV--------GSTEWTKA 4762
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
A + T + V L P TY F V N+ G
Sbjct: 4763 AFGNILDTKHRVTGLTPKKTYEFRVAAYNAAG 4794
Score = 34.7 bits (76), Expect = 0.40
Identities = 26/94 (27%), Positives = 32/94 (34%), Gaps = 5/94 (5%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-----TL 452
P I P N T+ A+ C +P P W+ +I R DG L
Sbjct: 661 PKIVEVPENVTVVENETAILTCKVSGSPAPTFRWFKGSREVISGGRFKHITDGKEHTVAL 720
Query: 453 VLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDS 486
L D G YT + HG LLV S
Sbjct: 721 ALLKCRSQDEGPYTLTIENVHGTDSADVKLLVTS 754
Score = 34.7 bits (76), Expect = 0.40
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 1/74 (1%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++ V Q +LN G P+P I W G V SD + G + SD
Sbjct: 2959 EIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRA-LRSD 3017
Query: 80 AGVYWCEATNSYGT 93
G Y +A N GT
Sbjct: 3018 TGTYIIKAENENGT 3031
Score = 34.7 bits (76), Expect = 0.40
Identities = 35/152 (23%), Positives = 61/152 (40%), Gaps = 15/152 (9%)
Query: 178 YQCIARNAAGTRESAIAT-----LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
++ IA NAAG + + T ++KP ++T + + G + + G P P
Sbjct: 3802 FRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPDPT 3861
Query: 233 VLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
W + G L ++D S+ + AD G Y + +N +G A +
Sbjct: 3862 ATW--TVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGEDEAIFEVI 3919
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D PS P +E +V + +C +P
Sbjct: 3920 VQDRPSAPEGP----LEVSDVTKDSCVLNWKP 3947
Score = 33.9 bits (74), Expect = 0.71
Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 3/82 (3%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT---LV 453
PPI+ +QT I V C II WY +G + + + + +G+ L
Sbjct: 377 PPIVLEASRSQTGRIGGSVVLEVQWQCHSSTIIEWYRDGTLVRNSSEYSQSFNGSIAKLQ 436
Query: 454 LKDLDKSDSGTYTCVASSRHGK 475
+ L + SG Y C A +G+
Sbjct: 437 VNKLTEEKSGLYKCHAKCDYGE 458
Score = 33.5 bits (73), Expect = 0.93
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 13/114 (11%)
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNVESGNVAR 311
+L ++N + D G+Y+CEA V LTV +PP +N PN+ + A
Sbjct: 866 TLIINNPEVDDTGKYTCEA----NGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAV 921
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
TC P + W G++ I G R AV G LTI + +++D
Sbjct: 922 LTC-KVNTPRAPLVW-YRGSKA-IQEGDPRFIIEKDAV--GRCTLTIKEVEEDD 970
Score = 32.7 bits (71), Expect = 1.6
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 12/100 (12%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P PP P+ T NVT + L W + + + Y +E+ +E SGN
Sbjct: 1272 VKDKPKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEM--QEGRSGN------- 1322
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
W + T + VK L Y F V+ N GLS P
Sbjct: 1323 -WAKVGE-TKGTDFKVKDLKEHGEYKFRVKALNECGLSDP 1360
Score = 32.3 bits (70), Expect = 2.2
Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 1/83 (1%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV + GG P P ++W+KG + + +I + + SD
Sbjct: 1782 ITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDV 1841
Query: 81 GVYWCEATNSYGTARSRNATLHV 103
G Y NS+G A A L V
Sbjct: 1842 GEYRLTVKNSHG-ADEEKANLTV 1863
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 11/101 (10%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P KP + + + W+ G + + GY VE + S W
Sbjct: 3731 VPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVE----------KKEKGSAIWTE 3780
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
A + T + +L PG+ Y F V N+ G S PS +D
Sbjct: 3781 -AGKTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTD 3820
Score = 32.3 bits (70), Expect = 2.2
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
+ D P P +E+ + + L W PP+ +G N VV D N + V ++
Sbjct: 3920 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPK---DDGGAEISNYVVEKRDTKTN-TWVPVS 3975
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
V TS+ + LT G Y ++ AE G
Sbjct: 3976 AFV-TGTSITVPKLTEGHEYEFRVMAENTFG 4005
Score = 31.9 bits (69), Expect = 2.9
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 12/94 (12%)
Query: 504 PGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
P P P+ +V + ++ LSW + G I Y+VE +T +G WV
Sbjct: 1867 PSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVE--KLDTATGR--------WVP 1916
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
A +V T + L G TY F V+ N G S
Sbjct: 1917 CA-KVKDTKAHIDGLKKGQTYQFRVKAVNKEGAS 1949
Score = 31.1 bits (67), Expect = 5.0
Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 11/111 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PGPP ++ T++W + G S I GY VE+ RE S W V
Sbjct: 5112 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEI--RE--------YGSTLWTVA 5161
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ V + + V L Y F V N+ G PS S + + + S
Sbjct: 5162 SDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 5212
Score = 30.3 bits (65), Expect = 8.7
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 11/123 (8%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD---DGSLRLD 260
+ G D+ + G+ + G+P P W+ A + G R V + ++ +
Sbjct: 3542 LAGLLDLRIKAGTPIKLDIAFEGEPAPVAKWK--ANDATIDTGARADVTNTPTSSAIHIF 3599
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ + D G Y EN G +A +TV D P P ++ + + CT +P
Sbjct: 3600 SAVRGDTGVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKID----EIHKEGCTLNWKP 3655
Query: 321 EPT 323
PT
Sbjct: 3656 -PT 3657
>X15423-1|CAA33463.1| 6048|Caenorhabditis elegans twitchin protein.
Length = 6048
Score = 76.6 bits (180), Expect = 1e-13
Identities = 86/324 (26%), Positives = 130/324 (40%), Gaps = 44/324 (13%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + +N E G F C +G P P W +G + ++ KY T + G
Sbjct: 4813 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRW-FKGCKELV----DTSKY--TLINKG 4865
Query: 353 -VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTV-TSDDDRPPPIITNGPSNQTLP 410
VL IND +D+ + C A N +G+ R L + T PP G Q
Sbjct: 4866 DKQVLIINDLTSDDA-DEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGE 4924
Query: 411 IKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTC 467
+ + P A P+ W +GE + N + ++T D TL + + + D G Y
Sbjct: 4925 TIELKI-PYKAY--PQGEARWTKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRV 4981
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQN 527
V + G SG + V V+ +P PP PI N+ D +V LSW
Sbjct: 4982 VVENSVGSD--SGTVNVT--------------VADVPEPPRFPIIENILDEAVILSWKPP 5025
Query: 528 NKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIV 587
G S + Y +E RE + G+ +P + T+ ++ L G Y F +
Sbjct: 5026 ALDGGSLVTNYTIE--KREAMGGSWSP---------CAKSRYTYTTIEGLRAGKQYEFRI 5074
Query: 588 RTENSHGLSGP-SPVSDSVTVGDD 610
EN HG S P P + + GD+
Sbjct: 5075 IAENKHGQSKPCEPTAPVLIPGDE 5098
Score = 73.7 bits (173), Expect = 7e-13
Identities = 52/192 (27%), Positives = 88/192 (45%), Gaps = 12/192 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
SGE P I+ D+ + T C GSP P RW+KG +V + +++ G
Sbjct: 4809 SGEGPKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGCKELVDTSKYTLINKGDKQ 4868
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPE---SKQSAQGDT 124
L + DA Y C ATNS GT RS A L + F + P+ ++ +G+T
Sbjct: 4869 VL-IINDLTSDDADEYTCRATNSSGT-RSTRANLRIKTKPRVF-IPPKYHGGYEAQKGET 4925
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCI 181
+ L+ +P + P+ W K+G+ + + +S+ + L I +A + D G Y+ +
Sbjct: 4926 IELK-IPYKAYPQGEARWTKDGEKI--ENNSKFSITTDDKFATLRISNASREDYGEYRVV 4982
Query: 182 ARNAAGTRESAI 193
N+ G+ +
Sbjct: 4983 VENSVGSDSGTV 4994
Score = 72.9 bits (171), Expect = 1e-12
Identities = 121/493 (24%), Positives = 190/493 (38%), Gaps = 72/493 (14%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAAGTRE 190
G P P+V W NG+ + G+S+ + + + A + +G+Y A N GT +
Sbjct: 1595 GEPAPDVTWSFNGKGI---GESKAQIENEPYISRFALPKALRKQSGKYTITATNINGT-D 1650
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGGNM 244
S +K+ KP GP +V T + GG+P+ ++ + G +
Sbjct: 1651 SVTINIKVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDDGGEPIEFYEIEKMNTKDGIWV 1710
Query: 245 PLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT------VYDPPSINLS 298
P GR D +D++ D ++ +A NS G T +D P
Sbjct: 1711 PCGRS---GDTHFTVDSLNKGDHYKFRVKAVNSEGPSDPLETETDILAKNPFDRPDRPGR 1767
Query: 299 PNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH----ATAVFDGV 353
P + +S +V ++ + P + +E R KY A V G
Sbjct: 1768 PEPTDWDSDHVDLKWDPPLSDGGAPIEEYQIE----------KRTKYGRWEPAITVPGGQ 1817
Query: 354 TVLTINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPI 411
T T+ D N+ V AVN G S K + + P I + N T+
Sbjct: 1818 TTATVPDLTPNEEYEFRVV-AVNKGGPSDPSDASKAVIAKPRNLKPHIDRDALKNLTIKA 1876
Query: 412 KSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLVLKDLDKSDSGTYTC 467
F P P + W++ I+N R N LV+K +++ DSGT+T
Sbjct: 1877 GQSISFDVPVSGEPAPTVTWHWPDNREIRNGGRVKLDNPEYQSKLVVKQMERGDSGTFTI 1936
Query: 468 VASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQ 526
A + +G+ + + ++D P +PN DVS + G VTL+W
Sbjct: 1937 KAVNANGEDEATVKINVIDKPTSPN----GPLDVSDVHG------------DHVTLNWRA 1980
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV-HQTHYVVKSLIPGITYMF 585
+ G I Y +E + +T SG WV A+ +T VV LIPG Y F
Sbjct: 1981 PDDDGGIPIENYVIEKY--DTASGR--------WVPAAKVAGDKTTAVVDGLIPGHEYKF 2030
Query: 586 IVRTENSHGLSGP 598
V N+ G S P
Sbjct: 2031 RVAAVNAEGESDP 2043
Score = 72.1 bits (169), Expect = 2e-12
Identities = 118/494 (23%), Positives = 170/494 (34%), Gaps = 39/494 (7%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
P I +P V Q A CR S P + W+K + G + L
Sbjct: 5475 PRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGL-- 5532
Query: 72 THGRVHSD-AGVYWCEATNSYGTARSRNATLHVAVLREEFRLEP-ESKQSAQGDTVVLEC 129
T RV D G Y A NSYGT + L+V E + EP E + A V E
Sbjct: 5533 TINRVKGDDKGEYTVRAKNSYGT-KEEIVFLNVTRHSEPLKFEPLEPMKKAPSPPRVEEF 5591
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ---DARQTDAGRYQCIARNAA 186
R +P + + L N I+ D D R Q R+
Sbjct: 5592 KERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDEDRVQVSFRSGV 5651
Query: 187 GTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+ E A + Y +T D+ V GG+P+P V R P
Sbjct: 5652 CSLEIFNARVD-DAGTYTVTATNDLGVDVSECVLTVQTKGGEPIPRVSSFR-------PR 5703
Query: 247 GRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY---DPPSINLSPNSVN 303
L G+ + AD S + S SA+ L + PS +
Sbjct: 5704 RAYDTLSTGTDVERSHSYADMRRRSLIRDVSPDVRSAADDLKTKITNELPSFTAQLSDSE 5763
Query: 304 VESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDK 363
E G A F+ +G+PEP + W G R S ++ A+ V G L I+D K
Sbjct: 5764 TEVGGSAEFSAAVSGQPEPLIEWLHNGERI----SESDSRFRASYV-AGKATLRISDAKK 5818
Query: 364 NDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD----------RPPPIITNGPSNQTLPIKS 413
+D +C A N AG R LTV D +T + +
Sbjct: 5819 SD-EGQYLCRASNSAGQEQTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGE 5877
Query: 414 MAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVAS 470
F TPE ++ W G+ L + +++ DG + + D SD+G Y
Sbjct: 5878 SVTFEARVQGTPEEVL-WMRNGQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVR 5936
Query: 471 SRHGKYVWSGALLV 484
S+ V +L+V
Sbjct: 5937 SKGTNLVSVASLVV 5950
Score = 68.1 bits (159), Expect = 4e-11
Identities = 57/180 (31%), Positives = 79/180 (43%), Gaps = 12/180 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRY 178
G V EC GSP P W K + L+ S+ L++ G+ L+I D DA Y
Sbjct: 4827 GRCVTFEC-EISGSPRPEYRWFKGCKELV--DTSKYTLINKGDKQVLIINDLTSDDADEY 4883
Query: 179 QCIARNAAGTRESAIATLKIHIKPYLITGPE---DVVAQTGSSVTFQCRVGGDPLPDVLW 235
C A N++GTR S A L+I KP + P+ AQ G ++ + P + W
Sbjct: 4884 TCRATNSSGTR-STRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIPYKAYPQGEARW 4942
Query: 236 RRSAGGGNMPLGRVKVLDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
+ DD +LR+ N D GEY ENSVG+ S + +TV D P
Sbjct: 4943 TKDGEKIENNSKFSITTDDKFATLRISNASREDYGEYRVVVENSVGSDSGTVNVTVADVP 5002
Score = 67.3 bits (157), Expect = 6e-11
Identities = 63/206 (30%), Positives = 93/206 (45%), Gaps = 32/206 (15%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRE 190
G PEP + W NG+ + + DSR ++ L I DA+++D G+Y C A N+AG +E
Sbjct: 5778 GQPEPLIEWLHNGERIS-ESDSRFRASYVAGKATLRISDAKKSDEGQYLCRASNSAG-QE 5835
Query: 191 SAIATLKIHIKPYLITGPE---------------DVVAQTGSSVTFQCRVGGDPLPDVLW 235
ATL + L+ G + G SVTF+ RV G P +VLW
Sbjct: 5836 QTRATLTVKGDQPLLNGHAGQAVESELRVTKHLGGEIVNNGESVTFEARVQGTP-EEVLW 5894
Query: 236 RRSAGGGNMPLG-RVKVLDDG---SLRLDNVILADEGEYSCEAEN-SVGAVSASGYLTV- 289
R+ G + G + + DG S +++ +D G Y E + VS + + V
Sbjct: 5895 MRN--GQELTNGDKTSISQDGETLSFTINSADASDAGHYQLEVRSKGTNLVSVASLVVVG 5952
Query: 290 --YDPPSINLSPNSVNVESGNVARFT 313
DPP L P+SV+ G FT
Sbjct: 5953 EKADPPVTRL-PSSVSAPLGGSTAFT 5977
Score = 66.1 bits (154), Expect = 1e-10
Identities = 123/504 (24%), Positives = 191/504 (37%), Gaps = 63/504 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG---GNLVIQDARQTDAGRYQCIARNAA 186
+P G P P V W + +G R+ L + LV++ + D+G + A NA
Sbjct: 1884 VPVSGEPAPTVTWHWPDNREIRNG-GRVKLDNPEYQSKLVVKQMERGDSGTFTIKAVNAN 1942
Query: 187 GTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRV----GGDPLPDVLWRR--S 238
G E AT+KI++ KP GP DV G VT R GG P+ + + + +
Sbjct: 1943 GEDE---ATVKINVIDKPTSPNGPLDVSDVHGDHVTLNWRAPDDDGGIPIENYVIEKYDT 1999
Query: 239 AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSASGYLTVYDP--- 292
A G +P +V D + +D +I E ++ A N+ G + G DP
Sbjct: 2000 ASGRWVPAAKVAG-DKTTAVVDGLIPGHEYKFRVAAVNAEGESDPLETFGTTLAKDPFDK 2058
Query: 293 PSINLSPNSVNVESGNV-ARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
P +P + + +V + A P + VE F D H A
Sbjct: 2059 PGKTNAPEITDWDKDHVDLEWKPPANDGGAPIEEYVVEMKDE--FSPFWNDVAHVPAGQT 2116
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
TV + + K + R A N AG + + PP+I S Q + +
Sbjct: 2117 NATVGNLKEGSKYEFR----IRAKNKAGLGDPSDSASAVAKARNVPPVIDRN-SIQEIKV 2171
Query: 412 KSMAVFPCTAICT--PEPIIAWYFEGEALIQNHRRNVTN-DG--TLVLKDLDKSDSGTYT 466
K+ F + P P I W FEG + + R + N DG +K +SD+GTY
Sbjct: 2172 KAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYI 2231
Query: 467 CVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWS 525
A + +G + V D P +P GP +T N+ L+W
Sbjct: 2232 IKAENENGTDTAEVKVTVLDHPSSPR-------------GP--LDVT-NIVKDGCDLAWK 2275
Query: 526 QNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMF 585
+ G + I Y +E ++ +G W T++ V L G Y F
Sbjct: 2276 EPEDDGGAEISHYVIE--KQDAATGR--------WTACGES-KDTNFHVDDLTQGHEYKF 2324
Query: 586 IVRTENSHGLSGPSPVSDSVTVGD 609
V+ N HG S P +++ D
Sbjct: 2325 RVKAVNRHGDSDPLEAREAIIAKD 2348
Score = 64.1 bits (149), Expect = 6e-10
Identities = 80/312 (25%), Positives = 116/312 (37%), Gaps = 45/312 (14%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P I + P A FTC A GRPEPT W G P SR ++ A+ DG
Sbjct: 4423 PQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRE---LPESSRYRFEAS---DG 4476
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIK 412
V TI + D+ V N GS L V + PP+I N LP
Sbjct: 4477 VYKFTIKEVWDIDAGEYTV-EVSNPYGSDTATANLVVQA-----PPVIEKDVPNTILPSG 4530
Query: 413 SMAVFPCTAICTPEPIIAWYFEGEA-----LIQNHRRNVTNDGTLVLKDLDKSDSGTYTC 467
+ YF G A L+ N + T+ + + D T
Sbjct: 4531 DLVRLKI------------YFSGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPA 4578
Query: 468 VASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQ 526
++ G+Y ++ + + F+ +V+ LP P P+ N+ ++ TLSW
Sbjct: 4579 LSVREAGRYEYT---VSNDSGEATTGFW--LNVTGLPEAPQGPLHISNIGPSTATLSWRP 4633
Query: 527 NNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
G S I Y VE + LS + WV + V +Y+V L Y F
Sbjct: 4634 PVTDGGSKITSYVVE---KRDLSKDE-------WVTVTSNVKDMNYIVTGLFENHEYEFR 4683
Query: 587 VRTENSHGLSGP 598
V +N +G+ P
Sbjct: 4684 VSAQNENGIGAP 4695
Score = 60.9 bits (141), Expect = 5e-09
Identities = 84/305 (27%), Positives = 118/305 (38%), Gaps = 30/305 (9%)
Query: 2 SDDYVT--SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVV-SDTHR 58
+DD T + E P Q D A + G P P I W G + SD+
Sbjct: 5741 ADDLKTKITNELPSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRF 5800
Query: 59 SILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV------------AVL 106
G LR + + SD G Y C A+NS G ++R ATL V +
Sbjct: 5801 RASYVAGKATLRISDAK-KSDEGQYLCRASNSAGQEQTR-ATLTVKGDQPLLNGHAGQAV 5858
Query: 107 REEFRLEPE--SKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN 164
E R+ + G++V E +G+PE V W +NGQ L +GD DG
Sbjct: 5859 ESELRVTKHLGGEIVNNGESVTFEA-RVQGTPE-EVLWMRNGQELT-NGDKTSISQDGET 5915
Query: 165 L--VIQDARQTDAGRYQCIARNAAGTRESAIATLKI---HIKPYLITGPEDVVAQTGSSV 219
L I A +DAG YQ R + GT ++A+L + P + P V A G S
Sbjct: 5916 LSFTINSADASDAGHYQLEVR-SKGTNLVSVASLVVVGEKADPPVTRLPSSVSAPLGGST 5974
Query: 220 TFQCRVGGDPLPDVLWRRSAG--GGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
F V W R + N + VK + L + NV D+G Y +
Sbjct: 5975 AFTIEFENVEGLTVQWFRGSEKIEKNERVKSVKTGNTFKLDIKNVEQDDDGIYVAKVVKE 6034
Query: 278 VGAVS 282
A++
Sbjct: 6035 KKAIA 6039
Score = 56.0 bits (129), Expect = 2e-07
Identities = 83/317 (26%), Positives = 122/317 (38%), Gaps = 41/317 (12%)
Query: 295 INLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
++L V++G T T P+P + W+ EG + + D T
Sbjct: 3339 LDLDGKEFRVKAGEPLVITIPFTASPQPDISWTKEGGKPLA----------GVETTDSQT 3388
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
L I T ++DS + AVN G + K+TV D+P P N T P S
Sbjct: 3389 KLVIPSTRRSDS-GPVKIKAVNPYGEAEANIKITVI---DKP-----GAPENITYPAVSR 3439
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
CT A +G A I ++ G+ + + SGT V HG
Sbjct: 3440 HT--CTLNWD-----APKDDGGAEIAGYKIEYQEVGSQIWDKVPGLISGTAYTVRGLEHG 3492
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLP-GPPTKPITHNVT--DTS-VTLSWSQNNKI 530
+ + + ++ + + + V P PP P T +T DT+ V+L+W+
Sbjct: 3493 QQ-YRFRIRAENAVGLSDYCQGVPVVIKDPFDPPGAPSTPEITGYDTNQVSLAWNPPRDD 3551
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIAR-RVHQTHYVVKSLIPGITYMFIVRT 589
G S ILGY VE F + R W + V T +V L TY F VR
Sbjct: 3552 GGSPILGYVVERFEK---------RGGGDWAPVKMPMVKGTECIVPGLHENETYQFRVRA 3602
Query: 590 ENSHGLSGPSPVSDSVT 606
N+ G PS S+ VT
Sbjct: 3603 VNAAGHGEPSNGSEPVT 3619
Score = 54.0 bits (124), Expect = 6e-07
Identities = 114/486 (23%), Positives = 176/486 (36%), Gaps = 52/486 (10%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQCIARNAAGT 188
+P G P P + W G + D +++ DG ++ A ++D G Y A N GT
Sbjct: 2181 IPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRALRSDTGTYIIKAENENGT 2240
Query: 189 RESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQCRV--GGDPLPD-VLWRRSAGGGN 243
++A + + P GP DV + + G + ++ GG + V+ ++ A G
Sbjct: 2241 -DTAEVKVTVLDHPSSPRGPLDVTNIVKDGCDLAWKEPEDDGGAEISHYVIEKQDAATGR 2299
Query: 244 MPL-GRVKVLDDGSLRLDNVILADEGEYSCEAENSVG---AVSASGYLTVYDPPSINLSP 299
G K D + +D++ E ++ +A N G + A + DP P
Sbjct: 2300 WTACGESK---DTNFHVDDLTQGHEYKFRVKAVNRHGDSDPLEAREAIIAKDPFDRADKP 2356
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTIN 359
+ + + T P +EG + S D A V G T++
Sbjct: 2357 GTPEIVDWDKDHADLKWTP-PADDGGAPIEGY-LVEMRTPSGDWVPAVTVGAGELTATVD 2414
Query: 360 DTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVF 417
+ V A+N AG S + V P I + Q + F
Sbjct: 2415 GLKPGQTYQFRV-KALNKAGESTPSDPSRTMVAKPRHLAPKINRDMFVAQRVKAGQTLNF 2473
Query: 418 PCTAICTPEPIIAWYFEGEALIQN---HRRNVTNDGT-LVLKDLDKSDSGTYTCVASSRH 473
P P I W+ G L H N T++ T L K ++DSG Y VA++
Sbjct: 2474 DVNVEGEPAPKIEWFLNGSPLSSGGNTHIDNNTDNNTKLTTKSTARADSGKYKIVATNES 2533
Query: 474 GKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH-NVTDTSVTLSWSQNNKIGS 532
GK + ++ NI +PG P P+ H ++T SV L W + G
Sbjct: 2534 GK--------DEHEVDVNI--------LDIPGAPEGPLRHKDITKESVVLKWDEPLDDGG 2577
Query: 533 SSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENS 592
S I Y VE ++ G WV T V L G Y F V+ N
Sbjct: 2578 SPITNYVVE---KQEDGGR--------WVPCG-ETSDTSLKVNKLSEGHEYKFRVKAVNR 2625
Query: 593 HGLSGP 598
G S P
Sbjct: 2626 QGTSAP 2631
Score = 51.6 bits (118), Expect = 3e-06
Identities = 110/454 (24%), Positives = 173/454 (38%), Gaps = 65/454 (14%)
Query: 167 IQDARQTDAGRYQCIARNAAGTRESAIATLKIHI------KPYLITGPEDVVAQTGSSVT 220
+ R+ + ++ +A NAAG ++ + I I +P ++ PED
Sbjct: 4382 VDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGSRPQIVVKPEDTAQPYNRRAV 4441
Query: 221 FQCRVGGDPLPDVLWRRSAGGGNMP-LGRVKV-LDDGSLR--LDNVILADEGEYSCEAEN 276
F C G P P W R+ G +P R + DG + + V D GEY+ E N
Sbjct: 4442 FTCEAVGRPEPTARWLRN--GRELPESSRYRFEASDGVYKFTIKEVWDIDAGEYTVEVSN 4499
Query: 277 SVGAVSASGYLTVYDPPSINLS-PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTII 335
G+ +A+ L V PP I PN++ + SG++ R +G + +++
Sbjct: 4500 PYGSDTATANLVVQAPPVIEKDVPNTI-LPSGDLVRLKIYFSG--------TAPFRHSLV 4550
Query: 336 FPGMSRDKYHAT---AVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
D H T FD ++TI ++ + N +G + L VT
Sbjct: 4551 LNREEIDMDHPTIRIVEFDDHILITIPALSVREA-GRYEYTVSNDSGEATTGFWLNVTGL 4609
Query: 393 DDRP--PPIITN-GPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTN- 448
+ P P I+N GPS TL + P T I ++ E L ++ VT+
Sbjct: 4610 PEAPQGPLHISNIGPSTATLSWRP----PVTD--GGSKITSYVVEKRDLSKDEWVTVTSN 4663
Query: 449 --DGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV-DSPINPNIHFFRAADVSSLPG 505
D ++ L ++ + A + +G GA LV + PI + F
Sbjct: 4664 VKDMNYIVTGLFENHEYEFRVSAQNENG----IGAPLVSEHPIIARLPF----------D 4709
Query: 506 PPTKPITHNVTDTS---VTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
PPT P+ + VTLSW + G + GY VE E +N
Sbjct: 4710 PPTSPLNLEIVQVGGDYVTLSWQRPLSDGGGRLRGYIVEKQEEEHDEWFRCNQNPS---- 4765
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
+Y V +LI G Y + V N GLS
Sbjct: 4766 -----PPNNYNVPNLIDGRKYRYRVFAVNDAGLS 4794
Score = 50.0 bits (114), Expect = 1e-05
Identities = 48/209 (22%), Positives = 82/209 (39%), Gaps = 17/209 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LR 258
P +++ D+ + G VTF+C + G P P+ W + + + +++ G L
Sbjct: 4813 PKIVSPLSDLNEEVGRCVTFECEISGSPRPEYRWFKGC-KELVDTSKYTLINKGDKQVLI 4871
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP---NSVNVESGNVARFTCT 315
++++ D EY+C A NS G S L + P + + P + G
Sbjct: 4872 INDLTSDDADEYTCRATNSSGTRSTRANLRIKTKPRVFIPPKYHGGYEAQKGETIELKIP 4931
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
P+ W+ +G + + K+ T D L I++ + D V
Sbjct: 4932 YKAYPQGEARWTKDGEKI-----ENNSKFSIT-TDDKFATLRISNASREDYGEYRVV-VE 4984
Query: 376 NYAGSSFVRGKLTVTSDDDRPP--PIITN 402
N GS +TV +D PP PII N
Sbjct: 4985 NSVGSDSGTVNVTV-ADVPEPPRFPIIEN 5012
Score = 49.2 bits (112), Expect = 2e-05
Identities = 51/221 (23%), Positives = 81/221 (36%), Gaps = 10/221 (4%)
Query: 107 REEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNL 165
R + ++PE V C G PEP W +NG+ L R DG
Sbjct: 4422 RPQIVVKPEDTAQPYNRRAVFTC-EAVGRPEPTARWLRNGRELPESSRYRFEASDGVYKF 4480
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV 225
I++ DAG Y N G+ ++A A L + P + + + +G V +
Sbjct: 4481 TIKEVWDIDAGEYTVEVSNPYGS-DTATANLVVQAPPVIEKDVPNTILPSGDLVRLKIYF 4539
Query: 226 GGD-PL-PDVLWRRSAGGGNMPLGRVKVLDDGSL-RLDNVILADEGEYSCEAENSVGAVS 282
G P ++ R + P R+ DD L + + + + G Y N G +
Sbjct: 4540 SGTAPFRHSLVLNREEIDMDHPTIRIVEFDDHILITIPALSVREAGRYEYTVSNDSGEAT 4599
Query: 283 ASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
+L V P P ++ N+ T T + RP T
Sbjct: 4600 TGFWLNVTGLPEAPQGPLHIS----NIGPSTATLSWRPPVT 4636
Score = 48.8 bits (111), Expect = 2e-05
Identities = 51/185 (27%), Positives = 79/185 (42%), Gaps = 32/185 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNV-TNDGTLVLKDLD--KSDSGTYTCVASSRHGKYVWSGA 481
P+PII + + +N R V N G +V+ +SD+G Y A++++GK
Sbjct: 3757 PKPIIDLFNGNSPIFENERTVVDVNPGEIVITTTGSKRSDAGPYKISATNKYGKDTCK-- 3814
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQV 540
++ F V PG PT PI ++ ++TLSW G +I Y V
Sbjct: 3815 ----------LNVF----VLDAPGKPTGPIRATDIQADAMTLSWRPPKDNGGDAITNYVV 3860
Query: 541 EVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSP 600
E + T G+ WV + V T V++L Y F VR EN +G+ P
Sbjct: 3861 E---KRTPGGD--------WVTVGHPVGTT-LRVRNLDANTPYEFRVRAENQYGVGEPLE 3908
Query: 601 VSDSV 605
D++
Sbjct: 3909 TDDAI 3913
Score = 48.4 bits (110), Expect = 3e-05
Identities = 24/91 (26%), Positives = 51/91 (56%), Gaps = 4/91 (4%)
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVI 263
G +D+ + G ++ + + G+PLP+ LW + G +GRVK+ + ++++N +
Sbjct: 691 GIKDLRLKVGETIKYDVPISGEPLPECLWVVN-GKPLKAVGRVKMSSERGKHIMKIENAV 749
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPS 294
AD G+++ +NS G+ ++ +TV P+
Sbjct: 750 RADSGKFTITLKNSSGSCDSTATVTVVGRPT 780
Score = 47.6 bits (108), Expect = 5e-05
Identities = 47/181 (25%), Positives = 85/181 (46%), Gaps = 12/181 (6%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
G+T+ + +P G P P W NG+ L G +M G +++ I++A + D+G++
Sbjct: 700 GETIKYD-VPISGEPLPECLWVVNGKPLKAVGRVKMSSERGKHIMKIENAVRADSGKFTI 758
Query: 181 IARNAAGTRESAIATLKIHIKPYLITGPEDV--VAQTGSSVTFQ--CRVGGDPLPDVLWR 236
+N++G+ +S AT+ + +P GP D+ V G+++++ GGDPL +
Sbjct: 759 TLKNSSGSCDST-ATVTVVGRPTPPKGPLDIADVCADGATLSWNPPDDDGGDPLTGYIVE 817
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYS--CEAENSVG---AVSASGYLTVYD 291
V +D + L L ++G Y +A N+ G +SA Y + D
Sbjct: 818 AQDMDNKGKYIEVGKVDPNTTTLKVNGLRNKGNYKFRVKAVNNEGESEPLSADQYTQIKD 877
Query: 292 P 292
P
Sbjct: 878 P 878
Score = 45.6 bits (103), Expect = 2e-04
Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 7/100 (7%)
Query: 209 EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS-----LRLDNVI 263
+ + + G++V ++ ++GG+P+P+V W + G + G +D L + + +
Sbjct: 989 KSITVKAGATVRWEVKIGGEPIPEVKWFK--GNQQLENGIQLTIDTRKNEHTILCIPSAM 1046
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVN 303
+D GEY +NS GA LTV D PS P V+
Sbjct: 1047 RSDVGEYRLTVKNSHGADEEKANLTVLDRPSKPNGPLEVS 1086
Score = 43.6 bits (98), Expect = 9e-04
Identities = 30/97 (30%), Positives = 40/97 (41%), Gaps = 6/97 (6%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRR----NVTNDGTLV 453
P T S+ + A F PEP+I W GE + ++ R V TL
Sbjct: 5753 PSFTAQLSDSETEVGGSAEFSAAVSGQPEPLIEWLHNGERISESDSRFRASYVAGKATLR 5812
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPI 488
+ D KSD G Y C AS+ G+ L V D P+
Sbjct: 5813 ISDAKKSDEGQYLCRASNSAGQEQTRATLTVKGDQPL 5849
Score = 42.7 bits (96), Expect = 0.002
Identities = 117/488 (23%), Positives = 174/488 (35%), Gaps = 59/488 (12%)
Query: 130 LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGT 188
+P RG P P W N + + D R+ D V++ A + AG Y A NA+G+
Sbjct: 1299 VPVRGEPPPKKEWIFNEKPV-DDQKIRIESEDYKTRFVLRGATRKHAGLYTLTATNASGS 1357
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRV----GGDPLP--DVLWRRSAGGG 242
+ ++ + + KP GP +V + +V GG P+ ++ A G
Sbjct: 1358 DKHSVEVIVLG-KPSSPLGPLEVSNVYEDRADLEWKVPEDDGGAPIDHYEIEKMDLATGR 1416
Query: 243 NMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV 302
+P GR + + N+ E ++ A N G S LT + L+ N
Sbjct: 1417 WVPCGRSETT---KTTVPNLQPGHEYKFRVRAVNKEG---ESDPLTT---NTAILAKNPY 1467
Query: 303 NVESGNVARFTCTATGRPEPTMFWSV--EGNRTI-IFPGMSRDK---YHATAVFDGVTVL 356
V G V + + + W+ +G I F +DK + V G
Sbjct: 1468 EV-PGKVDKPELVDWDKDHVDLAWNAPDDGGAPIEAFVIEKKDKNGRWEEALVVPGDQKT 1526
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVR--GKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
K SA N AG+ V + P I S+ T+ + +
Sbjct: 1527 ATVPNLKEGEEYQFRISARNKAGTGDPSDPSDRVVAKPRNLAPRIHREDLSDTTVKVGAT 1586
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASS 471
F P P + W F G+ I + + N+ L + SG YT A++
Sbjct: 1587 LKFIVHIDGEPAPDVTWSFNGKG-IGESKAQIENEPYISRFALPKALRKQSGKYTITATN 1645
Query: 472 RHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPI-THNVTDTSVTLSWSQNNKI 530
+G DS + NI V S P P PI +V + TL W
Sbjct: 1646 ING---------TDS-VTINI------KVKSKPTKPKGPIEVTDVFEDRATLDWKPPEDD 1689
Query: 531 GSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTE 590
G I Y++E T G WV R TH+ V SL G Y F V+
Sbjct: 1690 GGEPIEFYEIE--KMNTKDGI--------WVPCGRS-GDTHFTVDSLNKGDHYKFRVKAV 1738
Query: 591 NSHGLSGP 598
NS G S P
Sbjct: 1739 NSEGPSDP 1746
Score = 42.7 bits (96), Expect = 0.002
Identities = 25/88 (28%), Positives = 39/88 (44%), Gaps = 3/88 (3%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
+ G P I+ +P D ++ A C A G P P RW + G + + + G+
Sbjct: 4418 SGGSRPQIVVKPEDTAQPYNRRAVFTCEAVGRPEPTARWLRNGRELPESSRYRFEASDGV 4477
Query: 67 FFLRATHGRVHS-DAGVYWCEATNSYGT 93
+ + T V DAG Y E +N YG+
Sbjct: 4478 Y--KFTIKEVWDIDAGEYTVEVSNPYGS 4503
Score = 41.5 bits (93), Expect = 0.004
Identities = 45/153 (29%), Positives = 66/153 (43%), Gaps = 15/153 (9%)
Query: 178 YQCIARNAAGTRESAIATLKIHI-----KPYLITG--PEDVVAQTGSSVTFQCRVGGDPL 230
++ A NAAG E ++ ++ I +P + G D++A G P
Sbjct: 3994 FRVAAYNAAGQGEYSVNSVPITADNAPTRPKINMGMLTRDILAYAGERAKILVPFAASPA 4053
Query: 231 PDVLWRRSAGGGNMPLGRVKV-LDD--GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P V + + + RVKV D +L ++ L D G Y E ENS G+ SAS L
Sbjct: 4054 PKVTFSKGENKISPTDPRVKVEYSDFLATLTIEKSELTDGGLYFVELENSQGSDSASIRL 4113
Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D P+ SP + VE ++A CT P
Sbjct: 4114 KVVDKPA---SPQHIRVE--DIAPDCCTLYWMP 4141
Score = 40.3 bits (90), Expect = 0.008
Identities = 42/147 (28%), Positives = 64/147 (43%), Gaps = 18/147 (12%)
Query: 178 YQCIARNAAGTRE----SAIATLK-IHIKPYL---ITGPEDVVAQTGSSVTFQCRVGGDP 229
Y+ +A N AG + SA AT K +H P + G E V + G + P
Sbjct: 3306 YRVVAVNKAGPGQPSDSSAAATAKPMHEAPKFDLDLDGKEFRV-KAGEPLVITIPFTASP 3364
Query: 230 LPDVLWRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
PD+ W + G PL V+ D + L + + +D G +A N G A+ +T
Sbjct: 3365 QPDISWTKEGG---KPLAGVETTDSQTKLVIPSTRRSDSGPVKIKAVNPYGEAEANIKIT 3421
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCT 315
V D P +P ++ + V+R TCT
Sbjct: 3422 VIDKPG---APENITYPA--VSRHTCT 3443
Score = 39.9 bits (89), Expect = 0.011
Identities = 33/104 (31%), Positives = 47/104 (45%), Gaps = 9/104 (8%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P P +T S L+W++ + G + I GY VE ++ L N+ R +
Sbjct: 3627 PGAPDAPRVGKITKNSAELTWNRPLRDGGAPIDGYIVE---KKKLGDNDWTRCN------ 3677
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTV 607
+ V T + VK+L Y F V NS G PS SD V +
Sbjct: 3678 DKPVRDTAFEVKNLGEKEEYEFRVIAVNSAGEGEPSKPSDLVLI 3721
Score = 39.5 bits (88), Expect = 0.014
Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 6/127 (4%)
Query: 9 GEAPYIIEQPLDVTVARHQPATLNCR-AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
G + I D+TV + + AGG+P P I + G + + R+++
Sbjct: 3726 GRPIFDINNLKDITVRAGETIQIRIPYAGGNPKPIIDLFNGNSPIF-ENERTVVDVNPGE 3784
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR-LEPESKQSAQGDTVV 126
+ T G SDAG Y ATN YG L+V VL + P Q D +
Sbjct: 3785 IVITTTGSKRSDAGPYKISATNKYG---KDTCKLNVFVLDAPGKPTGPIRATDIQADAMT 3841
Query: 127 LECLPPR 133
L PP+
Sbjct: 3842 LSWRPPK 3848
Score = 38.7 bits (86), Expect = 0.025
Identities = 28/102 (27%), Positives = 38/102 (37%), Gaps = 8/102 (7%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P P ++ TL W + G S I Y VE G W +
Sbjct: 4119 PASPQHIRVEDIAPDCCTLYWMPPSSDGGSPITNYIVEKLDLRHSDGK--------WEKV 4170
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSV 605
+ V +Y V LI Y F VR E +G+S P ++D V
Sbjct: 4171 SSFVRNLNYTVGGLIKDNRYRFRVRAETQYGVSEPCELADVV 4212
Score = 38.7 bits (86), Expect = 0.025
Identities = 25/90 (27%), Positives = 38/90 (42%), Gaps = 2/90 (2%)
Query: 3 DDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILP 62
+++ AP+ + + ++ L C G+P+P I W K G V D +
Sbjct: 5589 EEFKERRSAPFFTFHLRNRLIQKNHQCKLTCSLQGNPNPTIEWMKDGHPVDED-RVQVSF 5647
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEATNSYG 92
G+ L + RV DAG Y ATN G
Sbjct: 5648 RSGVCSLEIFNARV-DDAGTYTVTATNDLG 5676
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/111 (30%), Positives = 44/111 (39%), Gaps = 11/111 (9%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P P P+ +VT S L+W G + I Y VE R+T + NT
Sbjct: 3129 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPKDDGGAEISNYVVE--KRDTKT--NT----- 3179
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGD 609
WV ++ V T V L G Y F V EN+ G S + V D
Sbjct: 3180 -WVPVSAFVTGTSITVPKLTEGHEYEFRVMAENTFGRSDSLNTDEPVLAKD 3229
Score = 36.3 bits (80), Expect = 0.13
Identities = 72/307 (23%), Positives = 115/307 (37%), Gaps = 29/307 (9%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
ATL + + W+ G + + + + L R+ D G Y C
Sbjct: 221 ATLETDVNDKDAEVVWWHDGKRIDIDGVKFKVESSNRKRRLIINGARIE-DHGEYKCT-- 277
Query: 89 NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T R + + +F + + + + D V L C + + P + W +NG+
Sbjct: 278 ----TKDDRTMAQLIVDAKNKFIVALKDTEVIEKDDVTLMC-QTKDTKTPGI-WFRNGKQ 331
Query: 149 L--LFDGDSRMHLVDGGN-LVIQDARQTDAGRYQCIARNAAGTRESA-IATLKIHIKPYL 204
+ + G +G + L I +A Y+ + AG R S + L+ +P L
Sbjct: 332 ISSMPGGKFETQSRNGTHTLKIGKIEMNEADVYEI---DQAGLRGSCNVTVLEAEKRPIL 388
Query: 205 ITGPEDVVAQTGS----SVTFQCRVG--GDPLPDVLWRRSAGGGNM-PLGRVKVLDD-GS 256
P+ + A+ G V FQ + GDP +L M L V + DD
Sbjct: 389 NWKPKKIEAKAGEPCVVKVPFQIKGTRRGDPKAQILKNGKPIDEEMRKLVEVIIKDDVAE 448
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNV-ARFTCT 315
+ N LAD G+++ E NS G A L V D P P +E+ NV A
Sbjct: 449 IVFKNPQLADTGKWALELGNSAGTALAPFELFVKDKP----KPPKGPLETKNVTAEGLDL 504
Query: 316 ATGRPEP 322
G P+P
Sbjct: 505 VWGTPDP 511
Score = 36.3 bits (80), Expect = 0.13
Identities = 26/91 (28%), Positives = 37/91 (40%), Gaps = 2/91 (2%)
Query: 201 KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLR 258
+P I P G S F CRV P V W + + +K + D L
Sbjct: 5474 QPRFIVKPYGTEVGEGQSANFYCRVIASSPPVVTWHKDDRELKQSVKYMKRYNGNDYGLT 5533
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYLTV 289
++ V D+GEY+ A+NS G +L V
Sbjct: 5534 INRVKGDDKGEYTVRAKNSYGTKEEIVFLNV 5564
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/102 (29%), Positives = 42/102 (41%), Gaps = 12/102 (11%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P P + T L W G S I+GYQV+ R+T SG W+
Sbjct: 4220 VPNQPEAPTVRDKDSTWAELEWDPPRD-GGSKIIGYQVQY--RDTSSGR--------WIN 4268
Query: 563 IARRV-HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+ Q H V L + F + +N+ G S PSP S+
Sbjct: 4269 AKMDLSEQCHARVTGLRQNGEFEFRIIAKNAAGFSKPSPPSE 4310
Score = 35.1 bits (77), Expect = 0.31
Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 11/100 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P + + ++W +K G + I Y VEV +T + W +
Sbjct: 882 PGKPGRPEITDFDADRIDIAWEPPHKDGGAPIEEYIVEVRDPDT----------KEWKEV 931
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
+RV T+ + L G Y F VR N G PS S+
Sbjct: 932 -KRVPDTNASISGLKEGKEYQFRVRAVNKAGPGQPSEPSE 970
Score = 35.1 bits (77), Expect = 0.31
Identities = 45/186 (24%), Positives = 66/186 (35%), Gaps = 33/186 (17%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P+ W + R +VTN T + + + D+G Y + + HGK
Sbjct: 2775 PAPVAKWKANDATIDTGARADVTNTPTSSAIHIFSAVRGDTGVYKIIVENEHGK------ 2828
Query: 482 LLVDSPINPNIHFFRAADVSSLPGPPTKPIT-HNVTDTSVTLSWSQNNKIGSSSILGYQV 540
N+ V +PG P P+ + TL+W G + +L Y V
Sbjct: 2829 ----DTAQCNV------TVLDVPGTPEGPLKIDEIHKEGCTLNWKPPTDNGGTDVLHYIV 2878
Query: 541 EVFSRETLSGNNTPRNSRG-WVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
E SRG W + T V K L+PG Y F V+ N G S P
Sbjct: 2879 EKMD-----------TSRGTWQEVGTFPDCTAKVNK-LVPGKEYAFRVKAVNLQGESKPL 2926
Query: 600 PVSDSV 605
+ +
Sbjct: 2927 EAEEPI 2932
Score = 35.1 bits (77), Expect = 0.31
Identities = 27/92 (29%), Positives = 39/92 (42%), Gaps = 11/92 (11%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PG P +P ++ ++TL W++ G + I GY +E RE S W
Sbjct: 3922 PGAPGQPEAVETSEEAITLQWTRPTSDGGAPIQGYVIE--KREV--------GSTEWTKA 3971
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHG 594
A + T + V L P TY F V N+ G
Sbjct: 3972 AFGNILDTKHRVTGLTPKKTYEFRVAAYNAAG 4003
Score = 34.7 bits (76), Expect = 0.40
Identities = 22/74 (29%), Positives = 29/74 (39%), Gaps = 1/74 (1%)
Query: 20 DVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
++ V Q +LN G P+P I W G V SD + G + SD
Sbjct: 2168 EIKVKAGQDFSLNIPVSGEPTPTITWTFEGTPVESDDRMKLNNEDGKTKFHVKRA-LRSD 2226
Query: 80 AGVYWCEATNSYGT 93
G Y +A N GT
Sbjct: 2227 TGTYIIKAENENGT 2240
Score = 34.7 bits (76), Expect = 0.40
Identities = 35/152 (23%), Positives = 61/152 (40%), Gaps = 15/152 (9%)
Query: 178 YQCIARNAAGTRESAIAT-----LKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPD 232
++ IA NAAG + + T ++KP ++T + + G + + G P P
Sbjct: 3011 FRVIAVNAAGPSDPSDPTDPQITKARYLKPKILTASRKIKIKAGFTHNLEVDFIGAPDPT 3070
Query: 233 VLWRRSAGGGNMPLGRVKVLD----DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLT 288
W + G L ++D S+ + AD G Y + +N +G A +
Sbjct: 3071 ATW--TVGDSGAALAPELLVDAKSSTTSIFFPSAKRADSGNYKLKVKNELGEDEAIFEVI 3128
Query: 289 VYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
V D PS P +E +V + +C +P
Sbjct: 3129 VQDRPSAPEGP----LEVSDVTKDSCVLNWKP 3156
Score = 33.5 bits (73), Expect = 0.93
Identities = 33/114 (28%), Positives = 50/114 (43%), Gaps = 13/114 (11%)
Query: 256 SLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPS----INLSPNSVNVESGNVAR 311
+L ++N + D G+Y+CEA V LTV +PP +N PN+ + A
Sbjct: 75 TLIINNPEVDDTGKYTCEA----NGVPTHAQLTVLEPPMKYSFLNPLPNTQEIYRTKQAV 130
Query: 312 FTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKND 365
TC P + W G++ I G R AV G LTI + +++D
Sbjct: 131 LTC-KVNTPRAPLVW-YRGSKA-IQEGDPRFIIEKDAV--GRCTLTIKEVEEDD 179
Score = 32.7 bits (71), Expect = 1.6
Identities = 30/100 (30%), Positives = 41/100 (41%), Gaps = 12/100 (12%)
Query: 500 VSSLPGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSR 558
V P PP P+ T NVT + L W + + + Y +E+ +E SGN
Sbjct: 481 VKDKPKPPKGPLETKNVTAEGLDLVWGTPDPDEGAPVKAYIIEM--QEGRSGN------- 531
Query: 559 GWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGP 598
W + T + VK L Y F V+ N GLS P
Sbjct: 532 -WAKVGE-TKGTDFKVKDLKEHGEYKFRVKALNECGLSDP 569
Score = 32.3 bits (70), Expect = 2.2
Identities = 21/83 (25%), Positives = 32/83 (38%), Gaps = 1/83 (1%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
+TV + GG P P ++W+KG + + +I + + SD
Sbjct: 991 ITVKAGATVRWEVKIGGEPIPEVKWFKGNQQLENGIQLTIDTRKNEHTILCIPSAMRSDV 1050
Query: 81 GVYWCEATNSYGTARSRNATLHV 103
G Y NS+G A A L V
Sbjct: 1051 GEYRLTVKNSHG-ADEEKANLTV 1072
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/101 (25%), Positives = 40/101 (39%), Gaps = 11/101 (10%)
Query: 503 LPGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
+P P KP + + + W+ G + + GY VE + S W
Sbjct: 2940 VPDPVDKPEVTDWDKDRIDIKWNPTANNGGAPVTGYIVE----------KKEKGSAIWTE 2989
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSD 603
A + T + +L PG+ Y F V N+ G S PS +D
Sbjct: 2990 -AGKTPGTTFSADNLKPGVEYEFRVIAVNAAGPSDPSDPTD 3029
Score = 32.3 bits (70), Expect = 2.2
Identities = 25/91 (27%), Positives = 39/91 (42%), Gaps = 5/91 (5%)
Query: 727 LDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAIN 786
+ D P P +E+ + + L W PP+ +G N VV D N + V ++
Sbjct: 3129 VQDRPSAPEGPLEVSDVTKDSCVLNWKPPK---DDGGAEISNYVVEKRDTKTN-TWVPVS 3184
Query: 787 TTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
V TS+ + LT G Y ++ AE G
Sbjct: 3185 AFV-TGTSITVPKLTEGHEYEFRVMAENTFG 3214
Score = 31.9 bits (69), Expect = 2.9
Identities = 28/94 (29%), Positives = 40/94 (42%), Gaps = 12/94 (12%)
Query: 504 PGPPTKPI-THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVV 562
P P P+ +V + ++ LSW + G I Y+VE +T +G WV
Sbjct: 1076 PSKPNGPLEVSDVFEDNLNLSWKPPDDDGGEPIEYYEVE--KLDTATGR--------WVP 1125
Query: 563 IARRVHQTHYVVKSLIPGITYMFIVRTENSHGLS 596
A +V T + L G TY F V+ N G S
Sbjct: 1126 CA-KVKDTKAHIDGLKKGQTYQFRVKAVNKEGAS 1158
Score = 31.1 bits (67), Expect = 5.0
Identities = 30/111 (27%), Positives = 43/111 (38%), Gaps = 11/111 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
PGPP ++ T++W + G S I GY VE+ RE S W V
Sbjct: 4321 PGPPIHVGAKSIGRNHCTITWMAPLEDGGSKITGYNVEI--RE--------YGSTLWTVA 4370
Query: 564 A-RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNS 613
+ V + + V L Y F V N+ G PS S + + + S
Sbjct: 4371 SDYNVREPEFTVDKLREFNDYEFRVVAINAAGKGIPSLPSGPIKIQESGGS 4421
Score = 30.3 bits (65), Expect = 8.7
Identities = 28/123 (22%), Positives = 49/123 (39%), Gaps = 11/123 (8%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLD---DGSLRLD 260
+ G D+ + G+ + G+P P W+ A + G R V + ++ +
Sbjct: 2751 LAGLLDLRIKAGTPIKLDIAFEGEPAPVAKWK--ANDATIDTGARADVTNTPTSSAIHIF 2808
Query: 261 NVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ + D G Y EN G +A +TV D P P ++ + + CT +P
Sbjct: 2809 SAVRGDTGVYKIIVENEHGKDTAQCNVTVLDVPGTPEGPLKID----EIHKEGCTLNWKP 2864
Query: 321 EPT 323
PT
Sbjct: 2865 -PT 2866
>AF016687-7|AAK72063.1| 881|Caenorhabditis elegans Hypothetical
protein T21D12.9a protein.
Length = 881
Score = 76.6 bits (180), Expect = 1e-13
Identities = 58/216 (26%), Positives = 85/216 (39%), Gaps = 16/216 (7%)
Query: 257 LRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
L LDNV + D EY C A N G+ S L VY P +P + + G A+F C
Sbjct: 579 LLLDNVAMTDNSEYQCVARNRFGSDFSTHVKLQVYQAPKFTYTPEDMPLLVGQTAKFLCA 638
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
ATG P P + W+ E I FP + + T D + ++ + D+ C A
Sbjct: 639 ATGTPRPEIKWAFE---QIPFPAAEARRLYVTPNDDHIYIMNVTKEDQG----AYTCHAT 691
Query: 376 NYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAIC---TPEPIIAWY 432
N AG + L V + P P + IK C + + W
Sbjct: 692 NVAGQTQASANLIVFENFFHYP----ESPDLSPMLIKKRDALKIDCSCDLISSRQRMVWK 747
Query: 433 FEGEALIQNHRRNVT-NDGTLVLKDLDKSDSGTYTC 467
+ + ++ + + ND L L SDSG Y+C
Sbjct: 748 RQQQVILFLKKAKFSDNDQILTLTQTTFSDSGEYSC 783
Score = 72.9 bits (171), Expect = 1e-12
Identities = 62/248 (25%), Positives = 103/248 (41%), Gaps = 16/248 (6%)
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
V+E PR + + + +T + +G + L++ + TD YQC+ARN
Sbjct: 540 VMENGQPRVLVQDSATFLSINRTAVVNGTFDERELAAAELLLDNVAMTDNSEYQCVARNR 599
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNM 244
G+ S L+++ P PED+ G + F C G P P++ W
Sbjct: 600 FGSDFSTHVKLQVYQAPKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFPAA 659
Query: 245 PLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD-----PPSINLS 298
R+ V +D + + NV D+G Y+C A N G AS L V++ P S +LS
Sbjct: 660 EARRLYVTPNDDHIYIMNVTKEDQGAYTCHATNVAGQTQASANLIVFENFFHYPESPDLS 719
Query: 299 PNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTI 358
P + +C + M W + + I+F + + K+ D +LT+
Sbjct: 720 PMLIKKRDALKIDCSCDLISSRQ-RMVWKRQ-QQVILF--LKKAKFS-----DNDQILTL 770
Query: 359 NDTDKNDS 366
T +DS
Sbjct: 771 TQTTFSDS 778
Score = 56.4 bits (130), Expect = 1e-07
Identities = 64/228 (28%), Positives = 92/228 (40%), Gaps = 23/228 (10%)
Query: 274 AENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGN 331
A+ V A+ + D P + V V + G ARFTC G ++ W V N
Sbjct: 484 ADLYVVAIDTANLTCHNDSPRAKIVRQPVEVSTLIGEKARFTCNVYGASPLSIEWRVMEN 543
Query: 332 ---RTIIFPGMSRDKYHATAVFDGV--------TVLTINDTDKNDSRNTIVCSAVNYAGS 380
R ++ + + TAV +G L +++ D+ + C A N GS
Sbjct: 544 GQPRVLVQDSATFLSINRTAVVNGTFDERELAAAELLLDNVAMTDN-SEYQCVARNRFGS 602
Query: 381 SF-VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL- 438
F KL V P T P + L + A F C A TP P I W FE
Sbjct: 603 DFSTHVKLQVYQ-----APKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFP 657
Query: 439 -IQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
+ R VT ND + + ++ K D G YTC A++ G+ S L+V
Sbjct: 658 AAEARRLYVTPNDDHIYIMNVTKEDQGAYTCHATNVAGQTQASANLIV 705
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/179 (24%), Positives = 75/179 (41%), Gaps = 17/179 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGG--L 66
+AP P D+ + Q A C A G+P P I+W ++ ++ R + +
Sbjct: 614 QAPKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFPAAEARRLYVTPNDDHI 673
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSA-----Q 121
+ + T D G Y C ATN G ++ +A L ++ E F PES + +
Sbjct: 674 YIMNVT----KEDQGAYTCHATNVAGQTQA-SANL---IVFENFFHYPESPDLSPMLIKK 725
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
D + ++C S + WK+ Q +LF ++ D L + +D+G Y C
Sbjct: 726 RDALKIDCSCDLISSRQRMVWKRQQQVILFLKKAKFSDND-QILTLTQTTFSDSGEYSC 783
>U49830-7|AAM98046.1| 774|Caenorhabditis elegans Neuronal igcam
protein 6, isoform c protein.
Length = 774
Score = 75.8 bits (178), Expect = 2e-13
Identities = 66/232 (28%), Positives = 104/232 (44%), Gaps = 16/232 (6%)
Query: 125 VVLECLPPRGSPEPNVYWKKNGQT---LLFDGDSRMHL-VDGGNLVIQDARQTDAGRYQC 180
V ECL +V W K+ + LL + R L +D L ++ A +TD+G YQC
Sbjct: 36 VSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQC 95
Query: 181 IARNAAG-TRESAIATLKIHIKPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRRS 238
+A N G + SA+ T+K + V A GS+V+ C P W
Sbjct: 96 VASNDVGSSSSSALLTVKDSAPVFPPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKW-AD 154
Query: 239 AGGGNMP-LGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINL 297
AGG +P GR++ ++G + ++ V+ D G + C A N +G A L V + PSI
Sbjct: 155 AGGSKLPQKGRIRD-EEGVISIEKVLHEDAGLFFCTAHNKLGKAHAQVQLIVVNKPSI-- 211
Query: 298 SPNSVNVESGNVA---RFTCTATGR-PEPTMFWSVEGNRTIIFPGMSRDKYH 345
N ++ E+ N++ TC + PE W + +P + + K H
Sbjct: 212 KTNFLDEETVNMSCEVELTCENSAECPEALFEWKINDRPAKEYPSL-KSKVH 262
Score = 53.6 bits (123), Expect = 8e-07
Identities = 67/259 (25%), Positives = 102/259 (39%), Gaps = 27/259 (10%)
Query: 184 NAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGG-DPLPDVLWRRSAGGG 242
NA G+ + +K+ P ++ G D + T S+V+F+C + D V W + A
Sbjct: 2 NAFGSAAGEVH-VKLRAPPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPI 60
Query: 243 N---MPLGRVKVL--DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSI-- 295
+P + K L D L L D G Y C A N VG+ S+S LTV D +
Sbjct: 61 VPLLLPAEKRKRLKIDHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVFP 120
Query: 296 -NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
N V G+ C P W+ G + G RD+ +G
Sbjct: 121 PNAMSRKVFAAFGSTVSIPCIFEASPRFHGKWADAGGSKLPQKGRIRDE-------EG-- 171
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
V++I D+ C+A N G + + +L V + P I TN +T+ +
Sbjct: 172 VISIEKVLHEDA-GLFFCTAHNKLGKAHAQVQLIVVN----KPSIKTNFLDEETVNMSCE 226
Query: 415 AVFPC--TAICTPEPIIAW 431
C +A C PE + W
Sbjct: 227 VELTCENSAEC-PEALFEW 244
Score = 43.2 bits (97), Expect = 0.001
Identities = 52/204 (25%), Positives = 87/204 (42%), Gaps = 18/204 (8%)
Query: 12 PYIIEQPLDVTVARHQPATLNCRAGGSPS-PAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P I++ D V + C + S ++ W+K +V +LPA L+
Sbjct: 19 PSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVP----LLLPAEKRKRLK 74
Query: 71 ATHGRVH------SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQG 122
H +H +D+GVY C A+N G++ S +A L V F S++ +A G
Sbjct: 75 IDHNVLHLKFADETDSGVYQCVASNDVGSS-SSSALLTVKDSAPVFPPNAMSRKVFAAFG 133
Query: 123 DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
TV + C+ SP + W G + L R+ + G + I+ DAG + C A
Sbjct: 134 STVSIPCI-FEASPRFHGKWADAGGSKL-PQKGRIR-DEEGVISIEKVLHEDAGLFFCTA 190
Query: 183 RNAAGTRESAIATLKIHIKPYLIT 206
N G + + + ++ KP + T
Sbjct: 191 HNKLGKAHAQVQLIVVN-KPSIKT 213
Score = 39.9 bits (89), Expect = 0.011
Identities = 29/105 (27%), Positives = 48/105 (45%), Gaps = 9/105 (8%)
Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCT-AICTPEPIIAWYFEGEALI------QNHRRNVT 447
R PP I G ++ +P +S F C + + W+ + + ++ + +R
Sbjct: 16 RAPPSILQGLHDRLVPTESNVSFECLLSNADSYSSVEWFKDAKPIVPLLLPAEKRKRLKI 75
Query: 448 NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV--DSPINP 490
+ L LK D++DSG Y CVAS+ G S L V +P+ P
Sbjct: 76 DHNVLHLKFADETDSGVYQCVASNDVGSSSSSALLTVKDSAPVFP 120
Score = 35.5 bits (78), Expect = 0.23
Identities = 48/203 (23%), Positives = 78/203 (38%), Gaps = 11/203 (5%)
Query: 276 NSVGAVSASGYLTVYDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRT 333
N+ G+ + ++ + PPSI L V ES NV+ F C + + + +
Sbjct: 2 NAFGSAAGEVHVKLRAPPSILQGLHDRLVPTES-NVS-FECLLSNADSYSSVEWFKDAKP 59
Query: 334 IIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDD 393
I+ + +K + V L + D+ DS C A N GSS LTV
Sbjct: 60 IVPLLLPAEKRKRLKIDHNV--LHLKFADETDS-GVYQCVASNDVGSSSSSALLTVK--- 113
Query: 394 DRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTL 452
D P N S + V PC +P W G + + R +G +
Sbjct: 114 DSAPVFPPNAMSRKVFAAFGSTVSIPCIFEASPRFHGKWADAGGSKLPQKGRIRDEEGVI 173
Query: 453 VLKDLDKSDSGTYTCVASSRHGK 475
++ + D+G + C A ++ GK
Sbjct: 174 SIEKVLHEDAGLFFCTAHNKLGK 196
>U55364-6|AAA97973.1| 2541|Caenorhabditis elegans Hypothetical protein
F21C10.7 protein.
Length = 2541
Score = 73.3 bits (172), Expect = 9e-13
Identities = 58/179 (32%), Positives = 88/179 (49%), Gaps = 14/179 (7%)
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG-NLVIQDARQTDAGRY 178
AQG+ E + G P PNV W +G+ L D R+ + G +L Q+ + + G+Y
Sbjct: 2324 AQGEATTFEGIVT-GWPAPNVEWTNDGRPLDLK-DIRVSNIGGRVSLNFQNCQLSHVGKY 2381
Query: 179 QCIARNAAGTRESAIATLKIH---IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW 235
C A+N +G S+ A L + I P I + GS + + RV GDP+P V+W
Sbjct: 2382 MCTAKNDSGVATSS-AQLVVRPKTIAPDFIQRLISEEIEEGSQLKWTVRVTGDPMPKVIW 2440
Query: 236 RRSAGGGNMP-LGRVKVLDDG----SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
R G +P V+++D G SL + V AD G+++C AEN G ++ L V
Sbjct: 2441 MRD--GFEIPDCEEVRIVDHGDGYHSLVIVKVEGADSGQFTCLAENIAGEARSTADLVV 2497
Score = 66.1 bits (154), Expect = 1e-10
Identities = 74/315 (23%), Positives = 119/315 (37%), Gaps = 35/315 (11%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG--GNMPLGRVKVLDDGSLRL 259
P +IT +D V G F R+ G+P P + W + NM + V +L +
Sbjct: 1125 PQIITQLKDDVVDEGCRYEFSARINGEPEPTISWLKDGIDVKSNMDYRQEYVNGVATLVI 1184
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVY------------DPPSINLSPNSVNVESG 307
+ + D EY+ +A N+ G S+S L V D P SV V G
Sbjct: 1185 EESFIEDTAEYTVKATNTGGTASSSASLIVKSRSAMSSAILEEDKPRFVKQMQSVQVNEG 1244
Query: 308 NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSR 367
AR C G+PEP + W E T + ++ H T D ++ +
Sbjct: 1245 ETARLDCVVVGKPEPEITWFKE--ETAV---KESERVHLTFSGDHCQMIIDKTVPLDTGI 1299
Query: 368 NTIVCSAV-----NYAGSSFVRGKLTVTSDDDRP------PPIITNGPSNQTLPIKSMAV 416
T+ V N+ V K +P PP+I +N T A
Sbjct: 1300 YTVRAKNVHGEVANFCQLRVVPKKQPPPQTPPKPRTPIQRPPVIQPALTNTTWQEGETAT 1359
Query: 417 FPCTAICTPEPIIAWYFEGEALIQNHRRNVT--NDG--TLVLKDLDKSDSGTYTCVASSR 472
+ P+P + W F + + + ++ DG L ++ + ++G YT VA +
Sbjct: 1360 LQVFSYGEPKPRVHWKFNDSPVQTSSQVQISEQEDGWSRLTIQQISPVNAGMYTVVAENE 1419
Query: 473 HGKYVWSGALLVDSP 487
G+ V +GA + P
Sbjct: 1420 IGEAV-TGATVHVQP 1433
Score = 64.9 bits (151), Expect = 3e-10
Identities = 82/319 (25%), Positives = 130/319 (40%), Gaps = 39/319 (12%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP II Q D V + R G P P I W K G+ V S+ G+ L
Sbjct: 1123 QAPQIITQLKDDVVDEGCRYEFSARINGEPEPTISWLKDGIDVKSNMDYRQEYVNGVATL 1182
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARS-------RNATLHVAVLREE---FRLEPESKQS 119
+ D Y +ATN+ GTA S + + A+L E+ F + +S Q
Sbjct: 1183 VIEESFI-EDTAEYTVKATNTGGTASSSASLIVKSRSAMSSAILEEDKPRFVKQMQSVQV 1241
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAG 176
+G+T L+C+ G PEP + W K +T + + + R+HL G+ ++I D G
Sbjct: 1242 NEGETARLDCVVV-GKPEPEITWFKE-ETAVKESE-RVHLTFSGDHCQMIIDKTVPLDTG 1298
Query: 177 RYQCIARNAAG------------TRESAIAT-----LKIHIKPYLITGPEDVVAQTGSSV 219
Y A+N G ++ T I P + + Q G +
Sbjct: 1299 IYTVRAKNVHGEVANFCQLRVVPKKQPPPQTPPKPRTPIQRPPVIQPALTNTTWQEGETA 1358
Query: 220 TFQCRVGGDPLPDVLWR-RSAGGGNMPLGRVKVLDDG--SLRLDNVILADEGEYSCEAEN 276
T Q G+P P V W+ + ++ +DG L + + + G Y+ AEN
Sbjct: 1359 TLQVFSYGEPKPRVHWKFNDSPVQTSSQVQISEQEDGWSRLTIQQISPVNAGMYTVVAEN 1418
Query: 277 SVGAVSASGYLTVYDPPSI 295
+G + +G TV+ PS+
Sbjct: 1419 EIGE-AVTG-ATVHVQPSL 1435
Score = 57.6 bits (133), Expect = 5e-08
Identities = 56/192 (29%), Positives = 78/192 (40%), Gaps = 15/192 (7%)
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG---SLRLDNVILADE 267
VVAQ G + TF+ V G P P+V W G + L ++V + G SL N L+
Sbjct: 2322 VVAQ-GEATTFEGIVTGWPAPNVEWTND--GRPLDLKDIRVSNIGGRVSLNFQNCQLSHV 2378
Query: 268 GEYSCEAENSVGAVSASGYLTVYDP---PSINLSPNSVNVESGNVARFTCTATGRPEPTM 324
G+Y C A+N G ++S L V P S +E G+ ++T TG P P +
Sbjct: 2379 GKYMCTAKNDSGVATSSAQLVVRPKTIAPDFIQRLISEEIEEGSQLKWTVRVTGDPMPKV 2438
Query: 325 FWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVR 384
W +G F ++ DG L I + DS C A N AG +
Sbjct: 2439 IWMRDG-----FEIPDCEEVRIVDHGDGYHSLVIVKVEGADS-GQFTCLAENIAGEARST 2492
Query: 385 GKLTVTSDDDRP 396
L V P
Sbjct: 2493 ADLVVRPQGTAP 2504
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/190 (25%), Positives = 79/190 (41%), Gaps = 12/190 (6%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGG-VLVVSDTHRSILPAGGL 66
+G P+ + + VA+ + T G P+P + W G L + D S + GG
Sbjct: 2308 TGHPPHFTQTLVSTVVAQGEATTFEGIVTGWPAPNVEWTNDGRPLDLKDIRVSNI--GGR 2365
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
L + ++ S G Y C A N G A S + + +F S++ +G +
Sbjct: 2366 VSLNFQNCQL-SHVGKYMCTAKNDSGVATSSAQLVVRPKTIAPDFIQRLISEEIEEGSQL 2424
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG----NLVIQDARQTDAGRYQCI 181
+ G P P V W ++G + + +VD G +LVI D+G++ C+
Sbjct: 2425 KW-TVRVTGDPMPKVIWMRDGFEI--PDCEEVRIVDHGDGYHSLVIVKVEGADSGQFTCL 2481
Query: 182 ARNAAGTRES 191
A N AG S
Sbjct: 2482 AENIAGEARS 2491
>AF106579-3|AAM45364.1| 4369|Caenorhabditis elegans Kettin (drosophila
actin-binding)homolog protein 1, isoform d protein.
Length = 4369
Score = 71.7 bits (168), Expect = 3e-12
Identities = 56/203 (27%), Positives = 96/203 (47%), Gaps = 16/203 (7%)
Query: 7 TSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGL 66
T G+AP + D+ + ++ PA +C+ GG P P I+W+K G + +D ++ GG
Sbjct: 4165 TQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGA 4224
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLR-----EEFRLEPESKQSAQ 121
+ L+ ++ + +DAG+Y A N G AR + A L+V + + EE + ++Q
Sbjct: 4225 YKLKFSN-IISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGKGAEEGPRYEAPRFTSQ 4282
Query: 122 GDTVVLE-------CLPPRGSPEPNVYWKKNGQTLLF-DGDSRMHLVDGGNLVIQDARQT 173
+V++ G P+P + W +N + + DG L I AR
Sbjct: 4283 IQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEISQSKGEAILRISAARNE 4342
Query: 174 DAGRYQCIARNAAGTRESAIATL 196
D Y+ A N AG + S++A L
Sbjct: 4343 DVAEYKVEASNPAG-KASSVANL 4364
Score = 62.1 bits (144), Expect = 2e-09
Identities = 57/218 (26%), Positives = 90/218 (41%), Gaps = 28/218 (12%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVD-GGNLVIQDARQTDAGRYQCIARNAAGTRESA 192
G+ V W K+G+ + + + +L I + AG Y NAAGT ES
Sbjct: 4096 GAAPVKVTWLKDGKEIKSTFRTLITTTPTNSSLHIGRLENSHAGEYTVRLENAAGTVES- 4154
Query: 193 IATLKIHIKPYLITGPE------DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPL 246
+A L + P+ D+ Q F C++GG+P P + W + G +P
Sbjct: 4155 LANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSCQIGGEPKPTIQWFKD--GQPLPN 4212
Query: 247 -GRVKVLDDG---SLRLDNVILADEGEYSCEAENSVGAVSASGYLTV------------- 289
R +V+++G L+ N+I D G Y A+N VG L V
Sbjct: 4213 DDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCKARLNVNLQKTGKGAEEGP 4272
Query: 290 -YDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFW 326
Y+ P + V+ G A+F+ +G P+PT+ W
Sbjct: 4273 RYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRW 4310
Score = 54.0 bits (124), Expect = 6e-07
Identities = 46/199 (23%), Positives = 84/199 (42%), Gaps = 15/199 (7%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM--HLVDG-GNL 165
+F + P+S + +TV G+P P++ W+K+ T++ G + DG G L
Sbjct: 306 QFLVHPQSVAAKAFETVTFSAKVV-GTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 364
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK----PYLITGPEDVVAQTGSSVTF 221
+I+ DA Y +ARN G+ +S + + K P + G SV
Sbjct: 365 IIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVKL 424
Query: 222 QCRVGGDPLPDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENS 277
C+ G+ + W + + GG+ + ++ +L ++N + + G Y C+A N
Sbjct: 425 YCKAAGEGV-SFKWFKDNEPISSGGSYAVDNKG--NETTLHINNATMKEGGWYRCDATNK 481
Query: 278 VGAVSASGYLTVYDPPSIN 296
G + G + V N
Sbjct: 482 HGTTTLKGRVVVNSRQKFN 500
Score = 52.8 bits (121), Expect = 1e-06
Identities = 53/193 (27%), Positives = 79/193 (40%), Gaps = 16/193 (8%)
Query: 118 QSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGD-SRMHLVDGGNLVIQDARQTDA 175
Q + D C L P G P V W+ NG + + S + L+I+ DA
Sbjct: 3330 QLNEADATAFVCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADA 3389
Query: 176 GRYQCIARNAAGTRES----AIATLKIHIKPYLITGPEDVVAQ--TGSSVTFQCRVG--G 227
G Y+C+A N G+ S A+ + P ++ D V G S+ +CRV
Sbjct: 3390 GEYKCVATNVKGSATSVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPIN 3449
Query: 228 DPLPDVLWRRSAGGGNMP-LGRVK-VLDDGSLRLDNVIL--ADEGEYSCEAENSVGAVSA 283
DP V W R+ G +P R K + G + LD + D G+Y N G +
Sbjct: 3450 DPRLHVEWLRN--GAPLPEASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3507
Query: 284 SGYLTVYDPPSIN 296
+TV PS++
Sbjct: 3508 KTKITVLPRPSLD 3520
Score = 52.0 bits (119), Expect = 2e-06
Identities = 51/199 (25%), Positives = 78/199 (39%), Gaps = 11/199 (5%)
Query: 292 PPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFD 351
PP + P SV ++ F+ G P P++ W + + T+I G KY D
Sbjct: 304 PPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQ-KSDGTVIQSG---GKYKIENGPD 359
Query: 352 GVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPI 411
G L I D +D+ + + A N GS R L V P T + TL
Sbjct: 360 GSGRLIIEKVDAHDA-DMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYD 418
Query: 412 KSMAVFPCTAICTPEPI-IAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTC 467
C A E + W+ + E + V N G TL + + + G Y C
Sbjct: 419 GDSVKLYCKA--AGEGVSFKWFKDNEPISSGGSYAVDNKGNETTLHINNATMKEGGWYRC 476
Query: 468 VASSRHGKYVWSGALLVDS 486
A+++HG G ++V+S
Sbjct: 477 DATNKHGTTTLKGRVVVNS 495
Score = 52.0 bits (119), Expect = 2e-06
Identities = 70/280 (25%), Positives = 106/280 (37%), Gaps = 33/280 (11%)
Query: 35 AGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATH-GRV-HSDAGVYWCEATNSYG 92
AG +P + W K G + S T R+++ + H GR+ +S AG Y N+ G
Sbjct: 4095 AGAAPVK-VTWLKDGKEIKS-TFRTLITTTPTN--SSLHIGRLENSHAGEYTVRLENAAG 4150
Query: 93 TARS-RNATLHVAVLR---EEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQT 148
T S N T+ + +F + Q C G P+P + W K+GQ
Sbjct: 4151 TVESLANLTVAPPTTQGKAPDFSARLNDLRIQQNGPAEFSC-QIGGEPKPTIQWFKDGQP 4209
Query: 149 LLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---- 201
L D R +V+ G L + TDAG Y+ +A+N G A L ++++
Sbjct: 4210 L--PNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKNGVGEARCK-ARLNVNLQKTGK 4266
Query: 202 ----------PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
P + + +V G F + G P P + W R+ G
Sbjct: 4267 GAEEGPRYEAPRFTSQIQPIVVDEGKGAQFSAQFSGFPDPTIRWYRNNEPVKHADGYEIS 4326
Query: 252 LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
G LR+ D EY EA N G S+ L +
Sbjct: 4327 QSKGEAILRISAARNEDVAEYKVEASNPAGKASSVANLVL 4366
Score = 50.8 bits (116), Expect = 6e-06
Identities = 52/199 (26%), Positives = 80/199 (40%), Gaps = 17/199 (8%)
Query: 202 PYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD--DGSLRL 259
P + P+ V A+ +VTF +V G P P + W++S G G+ K+ + DGS RL
Sbjct: 305 PQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGPDGSGRL 364
Query: 260 --DNVILADEGEYSCEAENSVGAVSASGYLTVY-----DPPSINLSPNSVNVESGNVARF 312
+ V D Y A N G+ + L V + P S + G+ +
Sbjct: 365 IIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYDGDSVKL 424
Query: 313 TCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVC 372
C A G E F + N I G +A T L IN+ + C
Sbjct: 425 YCKAAG--EGVSFKWFKDNEPISSGGS-----YAVDNKGNETTLHINNATMKEG-GWYRC 476
Query: 373 SAVNYAGSSFVRGKLTVTS 391
A N G++ ++G++ V S
Sbjct: 477 DATNKHGTTTLKGRVVVNS 495
Score = 46.0 bits (104), Expect = 2e-04
Identities = 24/83 (28%), Positives = 40/83 (48%), Gaps = 6/83 (7%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP------NSVNVESG 307
+ SL + + + GEY+ EN+ G V + LTV P + +P N + ++
Sbjct: 4125 NSSLHIGRLENSHAGEYTVRLENAAGTVESLANLTVAPPTTQGKAPDFSARLNDLRIQQN 4184
Query: 308 NVARFTCTATGRPEPTMFWSVEG 330
A F+C G P+PT+ W +G
Sbjct: 4185 GPAEFSCQIGGEPKPTIQWFKDG 4207
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/162 (26%), Positives = 67/162 (41%), Gaps = 8/162 (4%)
Query: 37 GSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
G P+ ++W G + S G+ L H + +DAG Y C ATN G+A S
Sbjct: 3347 GDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKH-LIAADAGEYKCVATNVKGSATS 3405
Query: 97 -----RNATLHVAVLREEFRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLL 150
++ + + +L + +GD++ LEC + P P +V W +NG L
Sbjct: 3406 VGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRLHVEWLRNGAPLP 3465
Query: 151 FDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARNAAGTRES 191
+ G +L I A D G Y+ + RN G S
Sbjct: 3466 EASRFKPTFEFGFVSLDILYAYPEDNGDYELVVRNDKGEARS 3507
Score = 44.0 bits (99), Expect = 7e-04
Identities = 47/191 (24%), Positives = 77/191 (40%), Gaps = 13/191 (6%)
Query: 6 VTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
+ + P + P V + T + + G+P+P++ W K V+ + + G
Sbjct: 299 LVNARPPQFLVHPQSVAAKAFETVTFSAKVVGTPTPSLTWQKSDGTVIQSGGKYKIENGP 358
Query: 66 LFFLRATHGRVHS-DAGVYWCEATNSYGTARSR---NATLHVAVLREEFRLEPESKQSAQ 121
R +V + DA +Y A N G+ +SR N + EF + +S
Sbjct: 359 DGSGRLIIEKVDAHDADMYMLVARNDGGSFQSRFSLNVLQAKSPEAPEFTGKFQSTTLYD 418
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GN---LVIQDARQTDAGR 177
GD+V L C + W K+ + + G + VD GN L I +A + G
Sbjct: 419 GDSVKLYC--KAAGEGVSFKWFKDNEPISSGGS---YAVDNKGNETTLHINNATMKEGGW 473
Query: 178 YQCIARNAAGT 188
Y+C A N GT
Sbjct: 474 YRCDATNKHGT 484
Score = 42.7 bits (96), Expect = 0.002
Identities = 26/102 (25%), Positives = 44/102 (43%), Gaps = 8/102 (7%)
Query: 293 PSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
P + ++ V ARF C TG P P + W + GN+ + + FDG
Sbjct: 3697 PQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCL-------HGHRFKLNFDG 3749
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
+ LT++ + +D+ +V A N G + L + +DD
Sbjct: 3750 LHYLTVSKSRISDA-GEVVAIARNTEGETISTATLDIFQNDD 3790
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/102 (31%), Positives = 46/102 (45%), Gaps = 4/102 (3%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP ++ V +QPA C G P P + W+ G + HR L GL +L
Sbjct: 3695 QAPQFTIPLRNLQVTENQPARFECAVTGYPRPKVTWFINGNQCLHG-HRFKLNFDGLHYL 3753
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
+ R+ SDAG A N+ G S ATL + ++FR
Sbjct: 3754 TVSKSRI-SDAGEVVAIARNTEGETIS-TATLDI-FQNDDFR 3792
Score = 41.5 bits (93), Expect = 0.004
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 6/89 (6%)
Query: 392 DDDRPPPIITNGPSNQT-LPIKSMAVFPC--TAICTPEPIIAWYFEGEALIQNHRRNVTN 448
D D PP T+ + L A C T + P +I W+ G+ + +R +
Sbjct: 3177 DADHGPPKFTSALAGPPELQEGQQAHLECQVTPVADPRLVIEWFHNGQPVNHTNRMKAIH 3236
Query: 449 D-GTLVLK--DLDKSDSGTYTCVASSRHG 474
D G +VL+ + DSGT+TC A+++HG
Sbjct: 3237 DFGFVVLQLTPAEPQDSGTWTCRATNQHG 3265
Score = 41.1 bits (92), Expect = 0.005
Identities = 24/77 (31%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 132 PRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGT 188
P P + W NG+ + SR+ +++ VI D QT D+G ++C+A+NAAG
Sbjct: 2807 PVDDPTLTINWFLNGEPM--SASSRVKMINDFGWVIMDIAQTEPRDSGEWKCVAKNAAGE 2864
Query: 189 RESAIATLKIHIKPYLI 205
S AT+++ K ++
Sbjct: 2865 AVST-ATIEVQGKEVIL 2880
Score = 37.9 bits (84), Expect = 0.043
Identities = 23/74 (31%), Positives = 38/74 (51%), Gaps = 9/74 (12%)
Query: 422 ICTPEPI------IAWYFEGEALIQNHRRNVTND---GTLVLKDLDKSDSGTYTCVASSR 472
+C EPI + W G + ++R + TN+ TL++K L +D+G Y CVA++
Sbjct: 3340 VCVLEPIGDPTLRVQWEHNGHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNV 3399
Query: 473 HGKYVWSGALLVDS 486
G G + V+S
Sbjct: 3400 KGSATSVGKIAVES 3413
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/94 (31%), Positives = 44/94 (46%), Gaps = 9/94 (9%)
Query: 391 SDDDRP--PPIITNGPSNQTLPIKS--MAVFPCTA--ICTPEPIIAWYFEGEALIQNHR- 443
SDDD PP+ T + T P+K C I P I W+ +G L+ R
Sbjct: 1583 SDDDAAAQPPVFTQQLTGPTEPLKEGQSVHMDCVVQPINDPSLRIEWFHDGRPLMFGSRI 1642
Query: 444 RNVTNDGTLVLKDLD--KSDSGTYTCVASSRHGK 475
R + + G + L+ L D+GTYTC A++ G+
Sbjct: 1643 RTIHDFGYVGLEFLHIHPEDTGTYTCKATNLIGE 1676
Score = 35.9 bits (79), Expect = 0.18
Identities = 27/90 (30%), Positives = 37/90 (41%), Gaps = 2/90 (2%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
+F + + Q + EC G P P V W NG L +++ L +
Sbjct: 3698 QFTIPLRNLQVTENQPARFECAVT-GYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVS 3756
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKI 198
+R +DAG IARN G S ATL I
Sbjct: 3757 KSRISDAGEVVAIARNTEGETIST-ATLDI 3785
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 3/61 (4%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGA 481
P+ + WY G L + RR + ND LV DL + D+G Y+ V + G+ SG
Sbjct: 2151 PKTSVQWYLNGNPLSASSRRILRNDFGLVSLDLQYTLGEDAGEYSVVVKNSEGEDRTSGQ 2210
Query: 482 L 482
L
Sbjct: 2211 L 2211
Score = 35.5 bits (78), Expect = 0.23
Identities = 26/94 (27%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 396 PPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA--WYFEGEALIQNHRRNVTNDGTLV 453
PP I S +L A F T +P + W+ GE + + R + ND V
Sbjct: 2780 PPRFIQQLTSPGSLVENQPAHFEATVEPVDDPTLTINWFLNGEPMSASSRVKMINDFGWV 2839
Query: 454 LKDL---DKSDSGTYTCVASSRHGKYVWSGALLV 484
+ D+ + DSG + CVA + G+ V + + V
Sbjct: 2840 IMDIAQTEPRDSGEWKCVAKNAAGEAVSTATIEV 2873
Score = 35.1 bits (77), Expect = 0.31
Identities = 25/84 (29%), Positives = 36/84 (42%), Gaps = 2/84 (2%)
Query: 110 FRLEPESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVI 167
F + S++ +G + LE L P P+ V W +G L + R L G +L I
Sbjct: 666 FHSDLRSQEVFEGQQIHLETKLTPINDPDLRVVWLLDGNELPSNDKYRQTLSHGFASLDI 725
Query: 168 QDARQTDAGRYQCIARNAAGTRES 191
D+G Y C A N G E+
Sbjct: 726 PQTSSNDSGLYSCRAFNKLGESEN 749
Score = 35.1 bits (77), Expect = 0.31
Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 2/70 (2%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT--LVLKDLDKSDSGTYTCVASSR 472
A F C P P + W+ G + HR + DG L + SD+G +A +
Sbjct: 3714 ARFECAVTGYPRPKVTWFINGNQCLHGHRFKLNFDGLHYLTVSKSRISDAGEVVAIARNT 3773
Query: 473 HGKYVWSGAL 482
G+ + + L
Sbjct: 3774 EGETISTATL 3783
Score = 34.7 bits (76), Expect = 0.40
Identities = 29/109 (26%), Positives = 48/109 (44%), Gaps = 13/109 (11%)
Query: 227 GDPLPDVLWRRSAGGGNMPLG-RVKVLDD---GSLRLDNVILADEGEYSCEAENSVGAVS 282
GDP V W + G +P R+ ++ +L + ++I AD GEY C A N G+ +
Sbjct: 3347 GDPTLRVQWEHN--GHPIPYSNRISCTNEFGVATLLIKHLIAADAGEYKCVATNVKGSAT 3404
Query: 283 ASGYLTV-----YDPPSI--NLSPNSVNVESGNVARFTCTATGRPEPTM 324
+ G + V D P + L + N+ G+ C T +P +
Sbjct: 3405 SVGKIAVESSTQIDAPQVVQQLVDSVENILEGDSIHLECRVTPINDPRL 3453
Score = 33.5 bits (73), Expect = 0.93
Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Query: 415 AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG---TLVLKDLDKSDSGTYTCVASS 471
A F C P+P I W+ +G+ L + R V +G L ++ +D+G Y VA +
Sbjct: 4187 AEFSCQIGGEPKPTIQWFKDGQPLPNDDRFQVVEEGGAYKLKFSNIISTDAGIYEIVAKN 4246
Query: 472 RHGK 475
G+
Sbjct: 4247 GVGE 4250
Score = 32.7 bits (71), Expect = 1.6
Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 5/80 (6%)
Query: 121 QGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDAGR 177
+G+ + LEC + P + W ++GQ+L G D G +L I DAG
Sbjct: 1209 EGEPIHLECQVNPINDNSLKIIWLRDGQSLPH-GHRFRTFYDFGFVSLDILGFYAQDAGT 1267
Query: 178 YQCIARNAAGTRESAIATLK 197
Y C A N+ G E+ +AT++
Sbjct: 1268 YTCRAENSLGQAET-VATIR 1286
Score = 32.7 bits (71), Expect = 1.6
Identities = 18/57 (31%), Positives = 30/57 (52%), Gaps = 3/57 (5%)
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHGKYVWSGAL 482
+ W+ + + ++ HR T D DL + D+G Y CVA++RHG+ + S L
Sbjct: 3594 VEWFKDKKPVLLGHRFRSTLDFGFACLDLLYALPDDTGEYHCVATNRHGQTMISAKL 3650
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 5/88 (5%)
Query: 10 EAPYIIEQPLD-VTVARHQPATLNCRAGGSPSPAIR--WYKGGVLVVSDTHRSILPAGGL 66
+AP IE PLD + Q A + P +R W+K G +++ + G
Sbjct: 1988 DAPQFIE-PLDSIDRMEFQSAHFQTKVTPQTDPNLRIQWFKDGQPLMNSNRFKLTTDFGY 2046
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTA 94
L H V D+GVY +A+N+ G A
Sbjct: 2047 ISLDIAH-TVPEDSGVYSVKASNAKGDA 2073
Score = 31.5 bits (68), Expect = 3.8
Identities = 19/58 (32%), Positives = 27/58 (46%), Gaps = 1/58 (1%)
Query: 39 PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
P+ + W K G + + I G+ L + H DAGVY C NS+G A+S
Sbjct: 819 PTLRVSWLKDGQPLPNANRIQIFQNFGVVSL-SLHPTYPEDAGVYTCVLFNSHGQAQS 875
Score = 31.5 bits (68), Expect = 3.8
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 8/72 (11%)
Query: 214 QTGSSVTFQCRVG--GDPLPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLD--NVILADE 267
+ G + +C+V D ++W R G ++P G R + D G + LD D
Sbjct: 1208 EEGEPIHLECQVNPINDNSLKIIWLRD--GQSLPHGHRFRTFYDFGFVSLDILGFYAQDA 1265
Query: 268 GEYSCEAENSVG 279
G Y+C AENS+G
Sbjct: 1266 GTYTCRAENSLG 1277
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/58 (36%), Positives = 25/58 (43%), Gaps = 3/58 (5%)
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLD---KSDSGTYTCVASSRHGKYVWSGALLVD 485
W F G L + R V ND V D+D DSG YT V + G+ S VD
Sbjct: 1496 WLFNGNPLKASSRYRVLNDFGFVSLDIDYIIAEDSGKYTLVVYNSAGRAETSCEFQVD 1553
Score = 31.1 bits (67), Expect = 5.0
Identities = 29/76 (38%), Positives = 35/76 (46%), Gaps = 7/76 (9%)
Query: 117 KQSAQ-GDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRM---HLVDGGNLVIQDAR 171
K+ AQ G ++ LEC L P P V W +NGQ L SR D NL I
Sbjct: 1734 KEDAQEGQSIRLECRLIPVNDPTMRVTWTRNGQPL--PEASRFMPARNFDYVNLDILALY 1791
Query: 172 QTDAGRYQCIARNAAG 187
D+G Y C A +A G
Sbjct: 1792 GEDSGVYTCKAVSAFG 1807
Score = 30.3 bits (65), Expect = 8.7
Identities = 31/136 (22%), Positives = 52/136 (38%), Gaps = 2/136 (1%)
Query: 54 SDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLE 113
S T ++LP L + THG ++ + + + + + EFR +
Sbjct: 3507 SKTKITVLPRPSLDYTSQTHGNQQDSLESHFKQHSQAKLQLTANDIYNESDKRAPEFRTQ 3566
Query: 114 PESKQSAQGDTVVLEC-LPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDAR 171
++ +G+ E + P P V W K+ + +L R L G L + A
Sbjct: 3567 LQNIGVLEGEFCRFETQVAPINDPYLKVEWFKDKKPVLLGHRFRSTLDFGFACLDLLYAL 3626
Query: 172 QTDAGRYQCIARNAAG 187
D G Y C+A N G
Sbjct: 3627 PDDTGEYHCVATNRHG 3642
>U41530-1|AAA83273.3| 636|Caenorhabditis elegans Hypothetical
protein SSSD1.1 protein.
Length = 636
Score = 70.9 bits (166), Expect = 5e-12
Identities = 70/281 (24%), Positives = 112/281 (39%), Gaps = 36/281 (12%)
Query: 12 PYIIEQPLDVTVARHQPATL--NCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
P II + + + A L C+A G+PSP I W + ++ + +L L
Sbjct: 40 PVIISPSKNAIIHKKVGADLIFECKAEGAPSPEITWSRNEQIISTSP---VLTLSNL--- 93
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR-NATLHVAVLREEFRLEPESKQSAQGDTVVLE 128
D G+Y C A N G + S + A + + L P +K +G V
Sbjct: 94 ------EEGDKGLYTCLAVNIEGNSTSSIDVRFTKATILD---LIPLNKTVIEGSNVFWH 144
Query: 129 CLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
C + + W + + + G+L +QD R++D+G Y C A+N+AG
Sbjct: 145 CHANAQATAISYSWLFEKKPIKTTSLGLRSNIRSGDLSLQDVRKSDSGWYTCEAKNSAGE 204
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGR 248
T K + + + P ++ + G V+ C+ GDP+P V W R
Sbjct: 205 ------TTKPPV--FTVAPPSEIKVRLGDQVSIPCQGFGDPMPIVYWIRDK--------- 247
Query: 249 VKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV 289
K ++ +L V D G Y C NSV +S L V
Sbjct: 248 -KRINQSTLTFKKVEHLDHGAYECVVANSVETISTRVMLLV 287
Score = 59.7 bits (138), Expect = 1e-08
Identities = 54/207 (26%), Positives = 81/207 (39%), Gaps = 21/207 (10%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G ++ EC G+P P + W +N Q + S + L + + + D G Y C+
Sbjct: 56 GADLIFEC-KAEGAPSPEITWSRNEQII---STSPV-------LTLSNLEEGDKGLYTCL 104
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP-DVLWR-RSA 239
A N G S+I ++ L P + GS+V + C W
Sbjct: 105 AVNIEGNSTSSI-DVRFTKATILDLIPLNKTVIEGSNVFWHCHANAQATAISYSWLFEKK 163
Query: 240 GGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSP 299
LG + G L L +V +D G Y+CEA+NS G + TV PPS
Sbjct: 164 PIKTTSLGLRSNIRSGDLSLQDVRKSDSGWYTCEAKNSAGETTKPPVFTV-APPS----- 217
Query: 300 NSVNVESGNVARFTCTATGRPEPTMFW 326
+ V G+ C G P P ++W
Sbjct: 218 -EIKVRLGDQVSIPCQGFGDPMPIVYW 243
Score = 56.8 bits (131), Expect = 9e-08
Identities = 64/281 (22%), Positives = 112/281 (39%), Gaps = 41/281 (14%)
Query: 194 ATLKIHIKPYLITGPEDVVA--QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV 251
A L +++ P +I+ ++ + + G+ + F+C+ G P P++ W R+ +
Sbjct: 32 AKLVVNVPPVIISPSKNAIIHKKVGADLIFECKAEGAPSPEITWSRN---------EQII 82
Query: 252 LDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVAR 311
L L N+ D+G Y+C A N G ++S + ++L P + V G+
Sbjct: 83 STSPVLTLSNLEEGDKGLYTCLAVNIEGNSTSSIDVRFTKATILDLIPLNKTVIEGSNVF 142
Query: 312 FTCTATGRPEPTMF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTI 370
+ C A + + W E P + + + G L++ D K+DS
Sbjct: 143 WHCHANAQATAISYSWLFEKK-----PIKTTSLGLRSNIRSGD--LSLQDVRKSDS-GWY 194
Query: 371 VCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIA 430
C A N AG + +PP PS + + PC P PI+
Sbjct: 195 TCEAKNSAGET------------TKPPVFTVAPPSEIKVRLGDQVSIPCQGFGDPMPIVY 242
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
W I++ +R N TL K ++ D G Y CV ++
Sbjct: 243 W-------IRDKKR--INQSTLTFKKVEHLDHGAYECVVAN 274
Score = 46.4 bits (105), Expect = 1e-04
Identities = 64/227 (28%), Positives = 94/227 (41%), Gaps = 33/227 (14%)
Query: 284 SGYLTVYDPPSINLSPNS---VNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMS 340
S L V PP I +SP+ ++ + G F C A G P P + WS N II
Sbjct: 31 SAKLVVNVPPVI-ISPSKNAIIHKKVGADLIFECKAEGAPSPEITWS--RNEQII----- 82
Query: 341 RDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPII 400
+T+ VLT+++ ++ D + C AVN G+S + T I+
Sbjct: 83 -----STS-----PVLTLSNLEEGD-KGLYTCLAVNIEGNSTSSIDVRFTK-----ATIL 126
Query: 401 TNGPSNQTLPIKSMAVFPCTAICTPEPI-IAWYFEGEALIQNHR--RNVTNDGTLVLKDL 457
P N+T+ S + C A I +W FE + + R+ G L L+D+
Sbjct: 127 DLIPLNKTVIEGSNVFWHCHANAQATAISYSWLFEKKPIKTTSLGLRSNIRSGDLSLQDV 186
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLP 504
KSDSG YTC A + G+ V P + R D S+P
Sbjct: 187 RKSDSGWYTCEAKNSAGETTKPPVFTVAPPSEIKV---RLGDQVSIP 230
Score = 35.5 bits (78), Expect = 0.23
Identities = 33/128 (25%), Positives = 50/128 (39%), Gaps = 23/128 (17%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ-GDTVVLECLPPRGSP 136
SD+G Y CEA NS G F + P S+ + GD V + C G P
Sbjct: 189 SDSGWYTCEAKNSAGETTKPPV----------FTVAPPSEIKVRLGDQVSIPC-QGFGDP 237
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
P VYW ++ + ++ L + D G Y+C+ N+ T + + L
Sbjct: 238 MPIVYWIRDKKR-----------INQSTLTFKKVEHLDHGAYECVVANSVETISTRVMLL 286
Query: 197 KIHIKPYL 204
KP +
Sbjct: 287 VEITKPQM 294
>AF016687-8|AAK72065.1| 737|Caenorhabditis elegans Hypothetical
protein T21D12.9c protein.
Length = 737
Score = 70.5 bits (165), Expect = 7e-12
Identities = 45/168 (26%), Positives = 73/168 (43%), Gaps = 2/168 (1%)
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNA 185
V+E PR + + + +T + +G + L++ + TD YQC+ARN
Sbjct: 540 VMENGQPRVLVQDSATFLSINRTAVVNGTFDERELAAAELLLDNVAMTDNSEYQCVARNR 599
Query: 186 AGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWR-RSAGGGNM 244
G+ S L+++ P PED+ G + F C G P P++ W
Sbjct: 600 FGSDFSTHVKLQVYQAPKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFPAA 659
Query: 245 PLGRVKVL-DDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
R+ V +D + + NV D+G Y+C A N G AS L V++
Sbjct: 660 EARRLYVTPNDDHIYIMNVTKEDQGAYTCHATNVAGQTQASANLIVFE 707
Score = 70.1 bits (164), Expect = 9e-12
Identities = 42/134 (31%), Positives = 58/134 (43%), Gaps = 8/134 (5%)
Query: 257 LRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
L LDNV + D EY C A N G+ S L VY P +P + + G A+F C
Sbjct: 579 LLLDNVAMTDNSEYQCVARNRFGSDFSTHVKLQVYQAPKFTYTPEDMPLLVGQTAKFLCA 638
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAV 375
ATG P P + W+ E I FP + + T D + ++ + D + C A
Sbjct: 639 ATGTPRPEIKWAFE---QIPFPAAEARRLYVTPNDDHIYIMNVTKED----QGAYTCHAT 691
Query: 376 NYAGSSFVRGKLTV 389
N AG + L V
Sbjct: 692 NVAGQTQASANLIV 705
Score = 56.4 bits (130), Expect = 1e-07
Identities = 64/228 (28%), Positives = 92/228 (40%), Gaps = 23/228 (10%)
Query: 274 AENSVGAVSASGYLTVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGN 331
A+ V A+ + D P + V V + G ARFTC G ++ W V N
Sbjct: 484 ADLYVVAIDTANLTCHNDSPRAKIVRQPVEVSTLIGEKARFTCNVYGASPLSIEWRVMEN 543
Query: 332 ---RTIIFPGMSRDKYHATAVFDGV--------TVLTINDTDKNDSRNTIVCSAVNYAGS 380
R ++ + + TAV +G L +++ D+ + C A N GS
Sbjct: 544 GQPRVLVQDSATFLSINRTAVVNGTFDERELAAAELLLDNVAMTDN-SEYQCVARNRFGS 602
Query: 381 SF-VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL- 438
F KL V P T P + L + A F C A TP P I W FE
Sbjct: 603 DFSTHVKLQVYQ-----APKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFP 657
Query: 439 -IQNHRRNVT-NDGTLVLKDLDKSDSGTYTCVASSRHGKYVWSGALLV 484
+ R VT ND + + ++ K D G YTC A++ G+ S L+V
Sbjct: 658 AAEARRLYVTPNDDHIYIMNVTKEDQGAYTCHATNVAGQTQASANLIV 705
Score = 33.1 bits (72), Expect = 1.2
Identities = 23/90 (25%), Positives = 38/90 (42%), Gaps = 7/90 (7%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRW-YKGGVLVVSDTHRSILPAGG--L 66
+AP P D+ + Q A C A G+P P I+W ++ ++ R + +
Sbjct: 614 QAPKFTYTPEDMPLLVGQTAKFLCAATGTPRPEIKWAFEQIPFPAAEARRLYVTPNDDHI 673
Query: 67 FFLRATHGRVHSDAGVYWCEATNSYGTARS 96
+ + T D G Y C ATN G ++
Sbjct: 674 YIMNVT----KEDQGAYTCHATNVAGQTQA 699
>AL022270-1|CAB63432.1| 1270|Caenorhabditis elegans Hypothetical
protein C26G2.1 protein.
Length = 1270
Score = 70.1 bits (164), Expect = 9e-12
Identities = 93/391 (23%), Positives = 149/391 (38%), Gaps = 48/391 (12%)
Query: 198 IHIKP-YLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL--WRRSAGG-------GNMP-- 245
IHI + + P ++ G S+TF+C P P V W+ + G G +P
Sbjct: 14 IHISSQFFLESPSNLSTIAGESITFRCSAEKSPEPIVYSQWKSNTGSLLGYHQEGILPGH 73
Query: 246 LGRVKVLDDGS----LRLDNVILADEGEYSCE-AENSVGAVSASGYLTVYDPPSI----N 296
GR + + L++ +V L D+GEY C+ G + A +L + PP + N
Sbjct: 74 QGRFSYIKQNAEELHLKITHVNLDDDGEYECQMLHPEEGPIRAKSFLNIIVPPQLVYFSN 133
Query: 297 LSPNS-VNVESGNVARFTCTATG-RPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVT 354
PNS + V+ TC +PEP + W ++G + + H F T
Sbjct: 134 YQPNSIIAVKENTPLNITCVVPNVKPEPEVLWYMDG-KVMSRDVKQASTPHLNKTFTVYT 192
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPP--PIITNGPSNQTLPIK 412
L + +D+ND I C A + + +R T D PP P + + L
Sbjct: 193 SLVV-QSDRNDHGKVITCEA--FQKETDIRITTNTTLDVLFPPSDPTVEILRNPSALRSG 249
Query: 413 SMAVFPCTAI-CTPEPIIAWYFEGEAL-----IQNHRRNVTNDGTLVLKDLDKSDSGTYT 466
C+ P P + WY E + L + + + N + + D + Y
Sbjct: 250 DNVTIACSVTGGNPPPDVFWYHENKRLQSHSTLDTRSKEIKNIYSFIASQND--NMAEYE 307
Query: 467 CVA-SSRHGKYVWSGALL-VDSPI-------NPNIHFFRAADV--SSLPGPPTKPITHNV 515
C A +SR G L V+ P NI + +A++ SLP P IT +
Sbjct: 308 CRANNSRTGNPKRKAMKLEVNYPPASVELFGESNIRYGSSANIQCKSLPSNPASQITWII 367
Query: 516 TDTSVTLSWSQNNKIGSSSILGYQVEVFSRE 546
SV + + + + V V S E
Sbjct: 368 NGRSVPTPTQREFVVENGIVSSSNVSVHSNE 398
Score = 68.1 bits (159), Expect = 4e-11
Identities = 78/346 (22%), Positives = 130/346 (37%), Gaps = 23/346 (6%)
Query: 21 VTVARHQPATLNCRAGG-SPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSD 79
+ V + P + C P P + WY G ++ D ++ P F T V SD
Sbjct: 140 IAVKENTPLNITCVVPNVKPEPEVLWYMDGKVMSRDVKQASTPHLNKTFTVYTSLVVQSD 199
Query: 80 AG----VYWCEATNSYGTAR-SRNATLHVAVLREEFRLEPESKQSA--QGDTVVLECLPP 132
V CEA R + N TL V + +E SA GD V + C
Sbjct: 200 RNDHGKVITCEAFQKETDIRITTNTTLDVLFPPSDPTVEILRNPSALRSGDNVTIACSVT 259
Query: 133 RGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTD-AGRYQCIARNA-AGTRE 190
G+P P+V+W + L + N+ A Q D Y+C A N+ G +
Sbjct: 260 GGNPPPDVFWYHENKRLQSHSTLDTRSKEIKNIYSFIASQNDNMAEYECRANNSRTGNPK 319
Query: 191 SAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCR-VGGDPLPDVLWRRSAGGGNMPLGRV 249
L+++ P + + + GSS QC+ + +P + W + P R
Sbjct: 320 RKAMKLEVNYPPASVELFGESNIRYGSSANIQCKSLPSNPASQITWIINGRSVPTPTQRE 379
Query: 250 KVLDDGSLRLDNV--------ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNS 301
V+++G + NV + A + C A N G+ + + + PP +
Sbjct: 380 FVVENGIVSSSNVSVHSNELSVEAHQINVECMATNPEGSSAKQHVIKIIAPPKAPIITGL 439
Query: 302 VNVE--SGNVARFTCTAT-GRPEPTMFWSVEGNRTIIFPGMSRDKY 344
+ + G++ TC A G P + W G+ + G + K+
Sbjct: 440 EDRKFFEGDIVNVTCEAQGGNPLAELSW-YRGSEKHLVKGRKKMKW 484
Score = 64.9 bits (151), Expect = 3e-10
Identities = 105/431 (24%), Positives = 167/431 (38%), Gaps = 55/431 (12%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGSPSPAI--RWYKGGVLVVSDTHRSILPA--GGLFF 68
+ +E P +++ + T C A SP P + +W ++ ILP G +
Sbjct: 20 FFLESPSNLSTIAGESITFRCSAEKSPEPIVYSQWKSNTGSLLGYHQEGILPGHQGRFSY 79
Query: 69 LRATHGRVH--------SDAGVYWCEATN-SYGTARSRNATLHVAV---LREEFRLEPES 116
++ +H D G Y C+ + G R++ + L++ V L +P S
Sbjct: 80 IKQNAEELHLKITHVNLDDDGEYECQMLHPEEGPIRAK-SFLNIIVPPQLVYFSNYQPNS 138
Query: 117 KQSAQGDTVV-LECLPPRGSPEPNVYWKKNGQTLLFD--GDSRMHL----VDGGNLVIQD 169
+ + +T + + C+ P PEP V W +G+ + D S HL +LV+Q
Sbjct: 139 IIAVKENTPLNITCVVPNVKPEPEVLWYMDGKVMSRDVKQASTPHLNKTFTVYTSLVVQS 198
Query: 170 ARQTDAGRYQCIA-RNAAGTRESAIATLKIHIKP-----YLITGPEDVVAQTGSSVTFQC 223
R C A + R + TL + P ++ P ++G +VT C
Sbjct: 199 DRNDHGKVITCEAFQKETDIRITTNTTLDVLFPPSDPTVEILRNPS--ALRSGDNVTIAC 256
Query: 224 RV-GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNV--ILADE----GEYSCEAEN 276
V GG+P PDV W N L LD S + N+ +A + EY C A N
Sbjct: 257 SVTGGNPPPDVFWYHE----NKRLQSHSTLDTRSKEIKNIYSFIASQNDNMAEYECRANN 312
Query: 277 S-VGAVSASGY-LTV-YDPPSINLSPNSVNVESGNVARFTC-TATGRPEPTMFWSVEGNR 332
S G L V Y P S+ L S N+ G+ A C + P + W + G R
Sbjct: 313 SRTGNPKRKAMKLEVNYPPASVELFGES-NIRYGSSANIQCKSLPSNPASQITWIING-R 370
Query: 333 TIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSD 392
++ P V + N+ + + C A N GSS + + + +
Sbjct: 371 SVPTPTQREFVVENGIVSSSNVSVHSNELSVEAHQINVECMATNPEGSSAKQHVIKIIA- 429
Query: 393 DDRPP--PIIT 401
PP PIIT
Sbjct: 430 ---PPKAPIIT 437
Score = 61.3 bits (142), Expect = 4e-09
Identities = 72/293 (24%), Positives = 118/293 (40%), Gaps = 20/293 (6%)
Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
+P + ++GD+ E L RG+P +++ W+KNG + FD G L +
Sbjct: 696 DPVTVVMSEGDSFK-ENLTVRGNPAISLWQWRKNG--VPFDHTIGRVFARGAVLSGKQLL 752
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLP 231
TDAG Y A N+ G+ I L + + + V+A TG +V +C G+P
Sbjct: 753 STDAGVYTLTATNSVGSTNITIK-LAVEYSARITSISTPVIAATGDTVLLECEADGEPSK 811
Query: 232 D--VLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASG--YL 287
+ W ++ G + + + LRL N GEY+C+A+N +G V A G +L
Sbjct: 812 ANMIHWYKN---GEILAAQHRGHKKAILRL-NATEQQSGEYTCKADNGIG-VPAEGQTFL 866
Query: 288 TVYDPPSINLSPNSVNVES--GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYH 345
V P + G VA+ C P W E + +I S+
Sbjct: 867 LVNSAPRVLPVARYAKTAGILGGVAKARCKVYAVPTVEFVW--EKDEQLIKKNSSKYSIV 924
Query: 346 ATAVFDGV--TVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRP 396
T + + L I + +D + C A N G+ + + + D P
Sbjct: 925 NTQIDYSTYESTLWIKNIVPDDYTKKVKCIARNSFGTDHLSIPIIPPTHPDEP 977
Score = 56.8 bits (131), Expect = 9e-08
Identities = 60/232 (25%), Positives = 100/232 (43%), Gaps = 23/232 (9%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAI-RWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
++ P+ V ++ N G+P+ ++ +W K GV T + G + +
Sbjct: 693 LVNDPVTVVMSEGDSFKENLTVRGNPAISLWQWRKNGV-PFDHTIGRVFARGAVLSGKQL 751
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQ--SAQGDTVVLECL 130
+ +DAGVY ATNS G S N T+ +AV R+ S +A GDTV+LEC
Sbjct: 752 ---LSTDAGVYTLTATNSVG---STNITIKLAV-EYSARITSISTPVIAATGDTVLLECE 804
Query: 131 PPRGSPEPN-VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTR 189
+ N ++W KNG+ L + H ++ +A + +G Y C A N G
Sbjct: 805 ADGEPSKANMIHWYKNGEIL-----AAQHRGHKKAILRLNATEQQSGEYTCKADNGIGVP 859
Query: 190 ESAIATLKIHIKPYLITGPEDVVAQT----GSSVTFQCRVGGDPLPDVLWRR 237
L ++ P ++ P A+T G +C+V P + +W +
Sbjct: 860 AEGQTFLLVNSAPRVL--PVARYAKTAGILGGVAKARCKVYAVPTVEFVWEK 909
Score = 39.1 bits (87), Expect = 0.019
Identities = 32/118 (27%), Positives = 47/118 (39%), Gaps = 2/118 (1%)
Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVL-WRRSAGGGNMPLGRVKVLDDGSLRLDNV 262
L+ P VV G S V G+P + WR++ + +GRV L +
Sbjct: 693 LVNDPVTVVMSEGDSFKENLTVRGNPAISLWQWRKNGVPFDHTIGRV-FARGAVLSGKQL 751
Query: 263 ILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRP 320
+ D G Y+ A NSVG+ + + L V I V +G+ C A G P
Sbjct: 752 LSTDAGVYTLTATNSVGSTNITIKLAVEYSARITSISTPVIAATGDTVLLECEADGEP 809
Score = 32.7 bits (71), Expect = 1.6
Identities = 77/334 (23%), Positives = 128/334 (38%), Gaps = 43/334 (12%)
Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIAT--LKIHIKPY-LITGPEDVVAQ---TGSS 218
L ++ R + R +C A NAA E I + L ++ P ++ P D Q G S
Sbjct: 543 LALRVDRTMNTQRLKCEATNAA-LDEPLIESQYLSVYYPPRRVLIRPADSGDQRLLVGKS 601
Query: 219 VTFQC-RVGGDPLPDVLWR--RSAGGGNMPLGRVKVLD---DGSLRLDNVI-LADEGEYS 271
C + +P + W+ R+ + LG V + + D ++NV+ EY
Sbjct: 602 ARLVCGTLSSNPAAHISWQFSRATDDNKVHLGDVSLNETTRDNGFNVENVLSFTPTEEYD 661
Query: 272 CEAENSVG-------AVSASGYLTVYDPPSINLS-PNSVNVESGNVARFTCTATGRPEPT 323
+ + +V+ S L V PP + ++ P +V + G+ + T G P +
Sbjct: 662 GTVVHCIANHPEWKHSVNTSFPLNVMYPPKMLVNDPVTVVMSEGDSFKENLTVRGNPAIS 721
Query: 324 MF-WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSF 382
++ W G + F + AV G +L+ TD +A N GS+
Sbjct: 722 LWQWRKNG---VPFDHTIGRVFARGAVLSGKQLLS---TDAG----VYTLTATNSVGSTN 771
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEP--IIAWYFEGEALIQ 440
+ KL V IT+ + + C A P +I WY GE L
Sbjct: 772 ITIKLAVEYSAR-----ITSISTPVIAATGDTVLLECEADGEPSKANMIHWYKNGEILAA 826
Query: 441 NHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
HR + ++ + + SG YTC A + G
Sbjct: 827 QHR---GHKKAILRLNATEQQSGEYTCKADNGIG 857
>U58729-3|AAM54204.1| 955|Caenorhabditis elegans Hypothetical
protein F02G3.1c protein.
Length = 955
Score = 69.3 bits (162), Expect = 2e-11
Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 12/220 (5%)
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
L ++ ++D G+Y+C+ E S ++ DPP S + E G A C
Sbjct: 111 LMINRPKISDGGKYTCKTEIQGEQQEVSAEISFVDPPKFLNVQESQHPEEGTRAEIVCEV 170
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G + +FW G + S+ Y + + +L I C+A
Sbjct: 171 EGTDQLEVFWQFNG---VTLDETSQRGYEFS---ENNQILYIPHFTAKKDDGIYNCNAAQ 224
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFE- 434
Y SSF + VT RP + + P N I+ + C A+ P+P W+FE
Sbjct: 225 Y--SSFETLSVNVTG-YARPTITVFDVP-NGNRGIEGHTIELKCGAVGKPKPTYKWFFED 280
Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
E I ++ +G L+++ L+ D+GTY CVA++ G
Sbjct: 281 DEVPIARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVG 320
Score = 63.7 bits (148), Expect = 8e-10
Identities = 54/202 (26%), Positives = 82/202 (40%), Gaps = 8/202 (3%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + C G+ + W GV + + R + L H D G+Y C A
Sbjct: 164 AEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPHFTAKKDDGIYNCNAA 223
Query: 89 --NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
+S+ T S N T + F + P + +G T+ L+C G P+P W
Sbjct: 224 QYSSFETL-SVNVTGYARPTITVFDV-PNGNRGIEGHTIELKC-GAVGKPKPTYKWFFED 280
Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
+ S H V+ G L+I+ DAG Y+C+A N G+ E L + +KP +
Sbjct: 281 DEVPI-ARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVGSNERTF-DLAVFLKPKVDL 338
Query: 207 GPEDVVAQTGSSVTFQCRVGGD 228
E VV + G V C G+
Sbjct: 339 KHEYVVKE-GDDVELVCSYHGE 359
Score = 58.8 bits (136), Expect = 2e-08
Identities = 71/299 (23%), Positives = 120/299 (40%), Gaps = 24/299 (8%)
Query: 36 GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95
G + I WY+ G L+ + L ++ SD G Y C+ T G +
Sbjct: 78 GAASDAKIEWYRDGKLIPRFGSTMTIERTYSNQLMINRPKI-SDGGKYTCK-TEIQGEQQ 135
Query: 96 SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
+A + V +F ES+ +G + C G+ + V+W+ NG TL +
Sbjct: 136 EVSAEISF-VDPPKFLNVQESQHPEEGTRAEIVC-EVEGTDQLEVFWQFNGVTL-DETSQ 192
Query: 156 RMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGTRESAIATLKIHIKPY------LIT 206
R + N ++ T D G Y C NAA + S+ TL +++ Y +
Sbjct: 193 RGYEFSENNQILYIPHFTAKKDDGIYNC---NAA--QYSSFETLSVNVTGYARPTITVFD 247
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVIL 264
P G ++ +C G P P W +P+ R +++G L ++++
Sbjct: 248 VPNGNRGIEGHTIELKCGAVGKPKPTYKWFFE--DDEVPIARSDKHNVEEGLLIIESLNS 305
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
D G Y C A N+VG+ + L V+ P ++L V V+ G+ C+ G T
Sbjct: 306 EDAGTYKCVANNTVGSNERTFDLAVFLKPKVDLKHEYV-VKEGDDVELVCSYHGEGHVT 363
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/121 (30%), Positives = 52/121 (42%), Gaps = 8/121 (6%)
Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQ 222
L I+ DA Y C N AGT IH P L TGP + + G++V+
Sbjct: 469 LTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIH-PPTLRHYTGPH-IRSFDGNTVSVY 526
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADE-GEYSCEAENSV 278
C V P P W ++ +++ GS L L+N +D G Y+C A+N V
Sbjct: 527 CDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGV 586
Query: 279 G 279
G
Sbjct: 587 G 587
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 235 WRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
W+R A N V+ ++ L + ++ L D +Y+C N G V+ + + PP
Sbjct: 446 WKRFADDVNNQRISVRAEENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPP 505
Query: 294 SI-NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
++ + + + GN C + P P W G + + G+S +
Sbjct: 506 TLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNG-KEVEANGVSIQIF----TQGS 560
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAG 379
T LT+ + D +D+ C A N G
Sbjct: 561 STKLTLENFDGSDNFGVYTCRADNGVG 587
Score = 40.7 bits (91), Expect = 0.006
Identities = 36/125 (28%), Positives = 54/125 (43%), Gaps = 9/125 (7%)
Query: 79 DAGVYWCEATNSYGTAR--SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
DA Y C +N GT ++ +H LR P + S G+TV + C P
Sbjct: 478 DAADYTCAVSNDAGTVNKVTQVGIIHPPTLRHY--TGPHIR-SFDGNTVSVYC-DVSAVP 533
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTD-AGRYQCIARNAAGTRESAI 193
P +W KNG+ + +G S G + L +++ +D G Y C A N G E I
Sbjct: 534 SPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGVGQLEKQI 593
Query: 194 ATLKI 198
+K+
Sbjct: 594 DVIKV 598
>U58729-2|AAM54203.1| 913|Caenorhabditis elegans Hypothetical
protein F02G3.1b protein.
Length = 913
Score = 69.3 bits (162), Expect = 2e-11
Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 12/220 (5%)
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
L ++ ++D G+Y+C+ E S ++ DPP S + E G A C
Sbjct: 84 LMINRPKISDGGKYTCKTEIQGEQQEVSAEISFVDPPKFLNVQESQHPEEGTRAEIVCEV 143
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G + +FW G + S+ Y + + +L I C+A
Sbjct: 144 EGTDQLEVFWQFNG---VTLDETSQRGYEFS---ENNQILYIPHFTAKKDDGIYNCNAAQ 197
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFE- 434
Y SSF + VT RP + + P N I+ + C A+ P+P W+FE
Sbjct: 198 Y--SSFETLSVNVTG-YARPTITVFDVP-NGNRGIEGHTIELKCGAVGKPKPTYKWFFED 253
Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
E I ++ +G L+++ L+ D+GTY CVA++ G
Sbjct: 254 DEVPIARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVG 293
Score = 63.7 bits (148), Expect = 8e-10
Identities = 54/202 (26%), Positives = 82/202 (40%), Gaps = 8/202 (3%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + C G+ + W GV + + R + L H D G+Y C A
Sbjct: 137 AEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPHFTAKKDDGIYNCNAA 196
Query: 89 --NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
+S+ T S N T + F + P + +G T+ L+C G P+P W
Sbjct: 197 QYSSFETL-SVNVTGYARPTITVFDV-PNGNRGIEGHTIELKC-GAVGKPKPTYKWFFED 253
Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
+ S H V+ G L+I+ DAG Y+C+A N G+ E L + +KP +
Sbjct: 254 DEVPI-ARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVGSNERTF-DLAVFLKPKVDL 311
Query: 207 GPEDVVAQTGSSVTFQCRVGGD 228
E VV + G V C G+
Sbjct: 312 KHEYVVKE-GDDVELVCSYHGE 332
Score = 58.8 bits (136), Expect = 2e-08
Identities = 71/299 (23%), Positives = 120/299 (40%), Gaps = 24/299 (8%)
Query: 36 GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95
G + I WY+ G L+ + L ++ SD G Y C+ T G +
Sbjct: 51 GAASDAKIEWYRDGKLIPRFGSTMTIERTYSNQLMINRPKI-SDGGKYTCK-TEIQGEQQ 108
Query: 96 SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
+A + V +F ES+ +G + C G+ + V+W+ NG TL +
Sbjct: 109 EVSAEISF-VDPPKFLNVQESQHPEEGTRAEIVC-EVEGTDQLEVFWQFNGVTL-DETSQ 165
Query: 156 RMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGTRESAIATLKIHIKPY------LIT 206
R + N ++ T D G Y C NAA + S+ TL +++ Y +
Sbjct: 166 RGYEFSENNQILYIPHFTAKKDDGIYNC---NAA--QYSSFETLSVNVTGYARPTITVFD 220
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVIL 264
P G ++ +C G P P W +P+ R +++G L ++++
Sbjct: 221 VPNGNRGIEGHTIELKCGAVGKPKPTYKWFFE--DDEVPIARSDKHNVEEGLLIIESLNS 278
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
D G Y C A N+VG+ + L V+ P ++L V V+ G+ C+ G T
Sbjct: 279 EDAGTYKCVANNTVGSNERTFDLAVFLKPKVDLKHEYV-VKEGDDVELVCSYHGEGHVT 336
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/121 (30%), Positives = 52/121 (42%), Gaps = 8/121 (6%)
Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQ 222
L I+ DA Y C N AGT IH P L TGP + + G++V+
Sbjct: 442 LTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIH-PPTLRHYTGPH-IRSFDGNTVSVY 499
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADE-GEYSCEAENSV 278
C V P P W ++ +++ GS L L+N +D G Y+C A+N V
Sbjct: 500 CDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGV 559
Query: 279 G 279
G
Sbjct: 560 G 560
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 235 WRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
W+R A N V+ ++ L + ++ L D +Y+C N G V+ + + PP
Sbjct: 419 WKRFADDVNNQRISVRAEENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPP 478
Query: 294 SI-NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
++ + + + GN C + P P W G + + G+S +
Sbjct: 479 TLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNG-KEVEANGVSIQIF----TQGS 533
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAG 379
T LT+ + D +D+ C A N G
Sbjct: 534 STKLTLENFDGSDNFGVYTCRADNGVG 560
Score = 40.7 bits (91), Expect = 0.006
Identities = 36/125 (28%), Positives = 54/125 (43%), Gaps = 9/125 (7%)
Query: 79 DAGVYWCEATNSYGTAR--SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
DA Y C +N GT ++ +H LR P + S G+TV + C P
Sbjct: 451 DAADYTCAVSNDAGTVNKVTQVGIIHPPTLRHY--TGPHIR-SFDGNTVSVYC-DVSAVP 506
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTD-AGRYQCIARNAAGTRESAI 193
P +W KNG+ + +G S G + L +++ +D G Y C A N G E I
Sbjct: 507 SPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGVGQLEKQI 566
Query: 194 ATLKI 198
+K+
Sbjct: 567 DVIKV 571
>U58729-1|AAM54202.1| 928|Caenorhabditis elegans Hypothetical
protein F02G3.1a protein.
Length = 928
Score = 69.3 bits (162), Expect = 2e-11
Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 12/220 (5%)
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
L ++ ++D G+Y+C+ E S ++ DPP S + E G A C
Sbjct: 84 LMINRPKISDGGKYTCKTEIQGEQQEVSAEISFVDPPKFLNVQESQHPEEGTRAEIVCEV 143
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G + +FW G + S+ Y + + +L I C+A
Sbjct: 144 EGTDQLEVFWQFNG---VTLDETSQRGYEFS---ENNQILYIPHFTAKKDDGIYNCNAAQ 197
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFE- 434
Y SSF + VT RP + + P N I+ + C A+ P+P W+FE
Sbjct: 198 Y--SSFETLSVNVTG-YARPTITVFDVP-NGNRGIEGHTIELKCGAVGKPKPTYKWFFED 253
Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
E I ++ +G L+++ L+ D+GTY CVA++ G
Sbjct: 254 DEVPIARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVG 293
Score = 63.7 bits (148), Expect = 8e-10
Identities = 54/202 (26%), Positives = 82/202 (40%), Gaps = 8/202 (3%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + C G+ + W GV + + R + L H D G+Y C A
Sbjct: 137 AEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPHFTAKKDDGIYNCNAA 196
Query: 89 --NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
+S+ T S N T + F + P + +G T+ L+C G P+P W
Sbjct: 197 QYSSFETL-SVNVTGYARPTITVFDV-PNGNRGIEGHTIELKC-GAVGKPKPTYKWFFED 253
Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
+ S H V+ G L+I+ DAG Y+C+A N G+ E L + +KP +
Sbjct: 254 DEVPI-ARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVGSNERTF-DLAVFLKPKVDL 311
Query: 207 GPEDVVAQTGSSVTFQCRVGGD 228
E VV + G V C G+
Sbjct: 312 KHEYVVKE-GDDVELVCSYHGE 332
Score = 58.8 bits (136), Expect = 2e-08
Identities = 71/299 (23%), Positives = 120/299 (40%), Gaps = 24/299 (8%)
Query: 36 GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95
G + I WY+ G L+ + L ++ SD G Y C+ T G +
Sbjct: 51 GAASDAKIEWYRDGKLIPRFGSTMTIERTYSNQLMINRPKI-SDGGKYTCK-TEIQGEQQ 108
Query: 96 SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
+A + V +F ES+ +G + C G+ + V+W+ NG TL +
Sbjct: 109 EVSAEISF-VDPPKFLNVQESQHPEEGTRAEIVC-EVEGTDQLEVFWQFNGVTL-DETSQ 165
Query: 156 RMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGTRESAIATLKIHIKPY------LIT 206
R + N ++ T D G Y C NAA + S+ TL +++ Y +
Sbjct: 166 RGYEFSENNQILYIPHFTAKKDDGIYNC---NAA--QYSSFETLSVNVTGYARPTITVFD 220
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVIL 264
P G ++ +C G P P W +P+ R +++G L ++++
Sbjct: 221 VPNGNRGIEGHTIELKCGAVGKPKPTYKWFFE--DDEVPIARSDKHNVEEGLLIIESLNS 278
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
D G Y C A N+VG+ + L V+ P ++L V V+ G+ C+ G T
Sbjct: 279 EDAGTYKCVANNTVGSNERTFDLAVFLKPKVDLKHEYV-VKEGDDVELVCSYHGEGHVT 336
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/121 (30%), Positives = 52/121 (42%), Gaps = 8/121 (6%)
Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQ 222
L I+ DA Y C N AGT IH P L TGP + + G++V+
Sbjct: 442 LTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIH-PPTLRHYTGPH-IRSFDGNTVSVY 499
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADE-GEYSCEAENSV 278
C V P P W ++ +++ GS L L+N +D G Y+C A+N V
Sbjct: 500 CDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGV 559
Query: 279 G 279
G
Sbjct: 560 G 560
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 235 WRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
W+R A N V+ ++ L + ++ L D +Y+C N G V+ + + PP
Sbjct: 419 WKRFADDVNNQRISVRAEENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPP 478
Query: 294 SI-NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
++ + + + GN C + P P W G + + G+S +
Sbjct: 479 TLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNG-KEVEANGVSIQIF----TQGS 533
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAG 379
T LT+ + D +D+ C A N G
Sbjct: 534 STKLTLENFDGSDNFGVYTCRADNGVG 560
Score = 40.7 bits (91), Expect = 0.006
Identities = 36/125 (28%), Positives = 54/125 (43%), Gaps = 9/125 (7%)
Query: 79 DAGVYWCEATNSYGTAR--SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
DA Y C +N GT ++ +H LR P + S G+TV + C P
Sbjct: 451 DAADYTCAVSNDAGTVNKVTQVGIIHPPTLRHY--TGPHIR-SFDGNTVSVYC-DVSAVP 506
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTD-AGRYQCIARNAAGTRESAI 193
P +W KNG+ + +G S G + L +++ +D G Y C A N G E I
Sbjct: 507 SPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGVGQLEKQI 566
Query: 194 ATLKI 198
+K+
Sbjct: 567 DVIKV 571
>AF456360-1|AAL60231.1| 928|Caenorhabditis elegans immunoglobulin
domain-containingprotein F02G3.1 protein.
Length = 928
Score = 69.3 bits (162), Expect = 2e-11
Identities = 56/220 (25%), Positives = 92/220 (41%), Gaps = 12/220 (5%)
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTA 316
L ++ ++D G+Y+C+ E S ++ DPP S + E G A C
Sbjct: 84 LMINRPKISDGGKYTCKTEIQGEQQEVSAEISFVDPPKFLNVQESQHPEEGTRAEIVCEV 143
Query: 317 TGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVN 376
G + +FW G + S+ Y + + +L I C+A
Sbjct: 144 EGTDQLEVFWQFNG---VTLDETSQRGYEFS---ENNQILYIPHFTAKKDDGIYNCNAAQ 197
Query: 377 YAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV-FPCTAICTPEPIIAWYFE- 434
Y SSF + VT RP + + P N I+ + C A+ P+P W+FE
Sbjct: 198 Y--SSFETLSVNVTG-YARPTITVFDVP-NGNRGIEGHTIELKCGAVGKPKPTYKWFFED 253
Query: 435 GEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
E I ++ +G L+++ L+ D+GTY CVA++ G
Sbjct: 254 DEVPIARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVG 293
Score = 63.7 bits (148), Expect = 8e-10
Identities = 54/202 (26%), Positives = 82/202 (40%), Gaps = 8/202 (3%)
Query: 29 ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEAT 88
A + C G+ + W GV + + R + L H D G+Y C A
Sbjct: 137 AEIVCEVEGTDQLEVFWQFNGVTLDETSQRGYEFSENNQILYIPHFTAKKDDGIYNCNAA 196
Query: 89 --NSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNG 146
+S+ T S N T + F + P + +G T+ L+C G P+P W
Sbjct: 197 QYSSFETL-SVNVTGYARPTITVFDV-PNGNRGIEGHTIELKC-GAVGKPKPTYKWFFED 253
Query: 147 QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLIT 206
+ S H V+ G L+I+ DAG Y+C+A N G+ E L + +KP +
Sbjct: 254 DEVPI-ARSDKHNVEEGLLIIESLNSEDAGTYKCVANNTVGSNERTF-DLAVFLKPKVDL 311
Query: 207 GPEDVVAQTGSSVTFQCRVGGD 228
E VV + G V C G+
Sbjct: 312 KHEYVVKE-GDDVELVCSYHGE 332
Score = 58.8 bits (136), Expect = 2e-08
Identities = 71/299 (23%), Positives = 120/299 (40%), Gaps = 24/299 (8%)
Query: 36 GGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTAR 95
G + I WY+ G L+ + L ++ SD G Y C+ T G +
Sbjct: 51 GAASDAKIEWYRDGKLIPRFGSTMTIERTYSNQLMINRPKI-SDGGKYTCK-TEIQGEQQ 108
Query: 96 SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDS 155
+A + V +F ES+ +G + C G+ + V+W+ NG TL +
Sbjct: 109 EVSAEISF-VDPPKFLNVQESQHPEEGTRAEIVC-EVEGTDQLEVFWQFNGVTL-DETSQ 165
Query: 156 RMHLVDGGNLVIQDARQT---DAGRYQCIARNAAGTRESAIATLKIHIKPY------LIT 206
R + N ++ T D G Y C NAA + S+ TL +++ Y +
Sbjct: 166 RGYEFSENNQILYIPHFTAKKDDGIYNC---NAA--QYSSFETLSVNVTGYARPTITVFD 220
Query: 207 GPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKV--LDDGSLRLDNVIL 264
P G ++ +C G P P W +P+ R +++G L ++++
Sbjct: 221 VPNGNRGIEGHTIELKCGAVGKPKPTYKWFFE--DDEVPIARSDKHNVEEGLLIIESLNS 278
Query: 265 ADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPT 323
D G Y C A N+VG+ + L V+ P ++L V V+ G+ C+ G T
Sbjct: 279 EDAGTYKCVANNTVGSNERTFDLAVFLKPKVDLKHEYV-VKEGDDVELVCSYHGEGHVT 336
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/121 (30%), Positives = 52/121 (42%), Gaps = 8/121 (6%)
Query: 165 LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYL--ITGPEDVVAQTGSSVTFQ 222
L I+ DA Y C N AGT IH P L TGP + + G++V+
Sbjct: 442 LTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIH-PPTLRHYTGPH-IRSFDGNTVSVY 499
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILADE-GEYSCEAENSV 278
C V P P W ++ +++ GS L L+N +D G Y+C A+N V
Sbjct: 500 CDVSAVPSPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGV 559
Query: 279 G 279
G
Sbjct: 560 G 560
Score = 41.5 bits (93), Expect = 0.004
Identities = 33/147 (22%), Positives = 59/147 (40%), Gaps = 7/147 (4%)
Query: 235 WRRSAGGGNMPLGRVKVLDDGS-LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPP 293
W+R A N V+ ++ L + ++ L D +Y+C N G V+ + + PP
Sbjct: 419 WKRFADDVNNQRISVRAEENKLILTIKSISLEDAADYTCAVSNDAGTVNKVTQVGIIHPP 478
Query: 294 SI-NLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDG 352
++ + + + GN C + P P W G + + G+S +
Sbjct: 479 TLRHYTGPHIRSFDGNTVSVYCDVSAVPSPKWHWFKNG-KEVEANGVSIQIF----TQGS 533
Query: 353 VTVLTINDTDKNDSRNTIVCSAVNYAG 379
T LT+ + D +D+ C A N G
Sbjct: 534 STKLTLENFDGSDNFGVYTCRADNGVG 560
Score = 40.7 bits (91), Expect = 0.006
Identities = 36/125 (28%), Positives = 54/125 (43%), Gaps = 9/125 (7%)
Query: 79 DAGVYWCEATNSYGTAR--SRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
DA Y C +N GT ++ +H LR P + S G+TV + C P
Sbjct: 451 DAADYTCAVSNDAGTVNKVTQVGIIHPPTLRHY--TGPHIR-SFDGNTVSVYC-DVSAVP 506
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGN--LVIQDARQTD-AGRYQCIARNAAGTRESAI 193
P +W KNG+ + +G S G + L +++ +D G Y C A N G E I
Sbjct: 507 SPKWHWFKNGKEVEANGVSIQIFTQGSSTKLTLENFDGSDNFGVYTCRADNGVGQLEKQI 566
Query: 194 ATLKI 198
+K+
Sbjct: 567 DVIKV 571
>U67954-3|AAM54178.1| 436|Caenorhabditis elegans
Wrapper/rega-1/klingon homologprotein 1, isoform a
protein.
Length = 436
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/171 (28%), Positives = 81/171 (47%), Gaps = 18/171 (10%)
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+V+ C G+P+P V W K L D R H G +VI + ++ AG+Y C+A N
Sbjct: 135 LVITCHVKEGNPKPGVVWTKQAAKLPED-IKREH--GGARIVITEVKKHHAGKYNCLAEN 191
Query: 185 AAGTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
AG+ AT+ IH+ KP++ + + + +F C G P+P V W +
Sbjct: 192 IAGSDR---ATIDIHVAEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKI 248
Query: 243 NMPLGRVKVLDDGSLRLDNVI--------LADE--GEYSCEAENSVGAVSA 283
N + K + + RL+ +++E G+Y+C N +G+V+A
Sbjct: 249 NFNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTA 299
Score = 61.3 bits (142), Expect = 4e-09
Identities = 68/295 (23%), Positives = 119/295 (40%), Gaps = 24/295 (8%)
Query: 101 LHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD------ 154
L +A + R + + + +G+++ L C P + W+KN + + D +
Sbjct: 11 LLIASTSAQIRTKGGTLIAKEGESLTLRCEVE--DPSVAIIWRKNTEVVAVDDEILDTYG 68
Query: 155 SRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV 212
++G L I+ ++ Y C A S +K+ +KP ++ P+ V
Sbjct: 69 GYEISMEGSTSVLTIKRVEPINSANYSCAL---AEPEVSVTFVIKVQVKPLVVISPDTGV 125
Query: 213 --AQTGS-SVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
A+ G ++ C V G+P P V+W + A +P + + + V G
Sbjct: 126 YHARVGEKNLVITCHVKEGNPKPGVVWTKQAA--KLPEDIKREHGGARIVITEVKKHHAG 183
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
+Y+C AEN G+ A+ + V + P + + V A F CT G P P + W
Sbjct: 184 KYNCLAENIAGSDRATIDIHVAEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLF 243
Query: 329 EGNRTIIFPGMSRDKYHATAV-FDGV--TVLTINDTDKNDSRNTIVCSAVNYAGS 380
G + I F K TA +G + LT+ D + ++ C N GS
Sbjct: 244 NGYK-INFNDEKFKKTSETAQRLNGYSKSTLTVGDISE-EAFGDYACRISNKLGS 296
Score = 31.1 bits (67), Expect = 5.0
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 10/102 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV------VSDTHRSILPA 63
E P++ + + V ++Q A+ C G+P P + W G + T +
Sbjct: 206 EKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEKFKKTSETAQRL 265
Query: 64 GGLFFLRATHGRVHSDA-GVYWCEATNSYGTARSRNATLHVA 104
G T G + +A G Y C +N G S A +HV+
Sbjct: 266 NGYSKSTLTVGDISEEAFGDYACRISNKLG---SVTAVVHVS 304
>S47168-1|AAB23867.2| 947|Caenorhabditis elegans UNC-5 protein.
Length = 947
Score = 68.1 bits (159), Expect = 4e-11
Identities = 57/211 (27%), Positives = 99/211 (46%), Gaps = 19/211 (9%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL-- 61
DY + + I QP V R++P L CRA + IR YK + D+ L
Sbjct: 24 DYKSIMDEITITTQPKSGYVIRNKPLRLQCRANHATK--IR-YKCSSKWIDDSRIEKLIG 80
Query: 62 --PAGGLFFLRATH--GRV------HSDAGVYWCEAT--NSYGTARSRNATLHVAVLREE 109
G+ ++ A+ R+ H DA C A+ + S AT+H+A +R+
Sbjct: 81 TDSTSGVGYIDASVDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDVATVHLAYMRKH 140
Query: 110 FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQD 169
F P +++ +G T+ L C P P+ + W K+G ++ D+ + G+L++
Sbjct: 141 FLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDG--VVVQPDANVIRASDGSLIMSA 198
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHI 200
AR +D+G Y C A N A +R++ ++I++
Sbjct: 199 ARLSDSGNYTCEATNVANSRKTDPVEVQIYV 229
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 160 VDGGNLVIQDARQTDAGRYQCIAR--NAAGTRESAIATLKI-HIKPYLITGPEDVVAQTG 216
VD + + + DA + QC A + S +AT+ + +++ + + P Q G
Sbjct: 94 VDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDVATVHLAYMRKHFLKSPVAQRVQEG 153
Query: 217 SSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275
+++ C+ DP ++ W + G P V DGSL + L+D G Y+CEA
Sbjct: 154 TTLQLPCQAPESDPKAELTWYKD-GVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEAT 212
Query: 276 N 276
N
Sbjct: 213 N 213
Score = 35.5 bits (78), Expect = 0.23
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 418 PCTAI-CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+ + WY +G + + +DG+L++ SDSG YTC A++
Sbjct: 159 PCQAPESDPKAELTWYKDGVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEATN 213
>AF456362-1|AAL60233.1| 435|Caenorhabditis elegans immunoglobulin
domain-containingprotein WRK-1A protein.
Length = 435
Score = 68.1 bits (159), Expect = 4e-11
Identities = 48/171 (28%), Positives = 81/171 (47%), Gaps = 18/171 (10%)
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+V+ C G+P+P V W K L D R H G +VI + ++ AG+Y C+A N
Sbjct: 134 LVITCHVKEGNPKPGVVWTKQAAKLPED-IKREH--GGARIVITEVKKHHAGKYNCLAEN 190
Query: 185 AAGTRESAIATLKIHI--KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGG 242
AG+ AT+ IH+ KP++ + + + +F C G P+P V W +
Sbjct: 191 IAGSDR---ATIDIHVAEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKI 247
Query: 243 NMPLGRVKVLDDGSLRLDNVI--------LADE--GEYSCEAENSVGAVSA 283
N + K + + RL+ +++E G+Y+C N +G+V+A
Sbjct: 248 NFNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTA 298
Score = 61.3 bits (142), Expect = 4e-09
Identities = 68/295 (23%), Positives = 119/295 (40%), Gaps = 24/295 (8%)
Query: 101 LHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD------ 154
L +A + R + + + +G+++ L C P + W+KN + + D +
Sbjct: 10 LLIASTSAQIRTKGGTLIAKEGESLTLRCEVE--DPSVAIIWRKNTEVVAVDDEILDTYG 67
Query: 155 SRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV 212
++G L I+ ++ Y C A S +K+ +KP ++ P+ V
Sbjct: 68 GYEISMEGSTSVLTIKRVEPINSANYSCAL---AEPEVSVTFVIKVQVKPLVVISPDTGV 124
Query: 213 --AQTGS-SVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
A+ G ++ C V G+P P V+W + A +P + + + V G
Sbjct: 125 YHARVGEKNLVITCHVKEGNPKPGVVWTKQAA--KLPEDIKREHGGARIVITEVKKHHAG 182
Query: 269 EYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSV 328
+Y+C AEN G+ A+ + V + P + + V A F CT G P P + W
Sbjct: 183 KYNCLAENIAGSDRATIDIHVAEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLF 242
Query: 329 EGNRTIIFPGMSRDKYHATAV-FDGV--TVLTINDTDKNDSRNTIVCSAVNYAGS 380
G + I F K TA +G + LT+ D + ++ C N GS
Sbjct: 243 NGYK-INFNDEKFKKTSETAQRLNGYSKSTLTVGDISE-EAFGDYACRISNKLGS 295
Score = 31.1 bits (67), Expect = 5.0
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 10/102 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV------VSDTHRSILPA 63
E P++ + + V ++Q A+ C G+P P + W G + T +
Sbjct: 205 EKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEKFKKTSETAQRL 264
Query: 64 GGLFFLRATHGRVHSDA-GVYWCEATNSYGTARSRNATLHVA 104
G T G + +A G Y C +N G S A +HV+
Sbjct: 265 NGYSKSTLTVGDISEEAFGDYACRISNKLG---SVTAVVHVS 303
>S47168-2|AAB23866.2| 919|Caenorhabditis elegans UNC-5 protein.
Length = 919
Score = 66.9 bits (156), Expect = 8e-11
Identities = 55/201 (27%), Positives = 95/201 (47%), Gaps = 19/201 (9%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAGGLFFL 69
I QP V R++P L CRA + IR YK + D+ L G+ ++
Sbjct: 6 ITTQPKSGYVIRNKPLRLQCRANHATK--IR-YKCSSKWIDDSRIEKLIGTDSTSGVGYI 62
Query: 70 RATH--GRV------HSDAGVYWCEAT--NSYGTARSRNATLHVAVLREEFRLEPESKQS 119
A+ R+ H DA C A+ + S AT+H+A +R+ F P +++
Sbjct: 63 DASVDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDVATVHLAYMRKHFLKSPVAQRV 122
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
+G T+ L C P P+ + W K+G ++ D+ + G+L++ AR +D+G Y
Sbjct: 123 QEGTTLQLPCQAPESDPKAELTWYKDG--VVVQPDANVIRASDGSLIMSAARLSDSGNYT 180
Query: 180 CIARNAAGTRESAIATLKIHI 200
C A N A +R++ ++I++
Sbjct: 181 CEATNVANSRKTDPVEVQIYV 201
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 160 VDGGNLVIQDARQTDAGRYQCIAR--NAAGTRESAIATLKI-HIKPYLITGPEDVVAQTG 216
VD + + + DA + QC A + S +AT+ + +++ + + P Q G
Sbjct: 66 VDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDVATVHLAYMRKHFLKSPVAQRVQEG 125
Query: 217 SSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275
+++ C+ DP ++ W + G P V DGSL + L+D G Y+CEA
Sbjct: 126 TTLQLPCQAPESDPKAELTWYKD-GVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEAT 184
Query: 276 N 276
N
Sbjct: 185 N 185
Score = 37.9 bits (84), Expect = 0.043
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGS-PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
+ ++ P+ V L C+A S P + WYK GV+V D + I + G + A
Sbjct: 112 HFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDAN-VIRASDGSLIMSA 170
Query: 72 THGRVHSDAGVYWCEATN 89
SD+G Y CEATN
Sbjct: 171 AR---LSDSGNYTCEATN 185
Score = 35.5 bits (78), Expect = 0.23
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 418 PCTAI-CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+ + WY +G + + +DG+L++ SDSG YTC A++
Sbjct: 131 PCQAPESDPKAELTWYKDGVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEATN 185
>AF036698-5|AAB88356.2| 567|Caenorhabditis elegans Uncoordinated
protein 5, isoform b protein.
Length = 567
Score = 66.9 bits (156), Expect = 8e-11
Identities = 55/201 (27%), Positives = 95/201 (47%), Gaps = 19/201 (9%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAGGLFFL 69
I QP V R++P L CRA + IR YK + D+ L G+ ++
Sbjct: 6 ITTQPKSGYVIRNKPLRLQCRANHATK--IR-YKCSSKWIDDSRIEKLIGTDSTSGVGYI 62
Query: 70 RATH--GRV------HSDAGVYWCEAT--NSYGTARSRNATLHVAVLREEFRLEPESKQS 119
A+ R+ H DA C A+ + S AT+H+A +R+ F P +++
Sbjct: 63 DASVDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDVATVHLAYMRKHFLKSPVAQRV 122
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
+G T+ L C P P+ + W K+G ++ D+ + G+L++ AR +D+G Y
Sbjct: 123 QEGTTLQLPCQAPESDPKAELTWYKDG--VVVQPDANVIRASDGSLIMSAARLSDSGNYT 180
Query: 180 CIARNAAGTRESAIATLKIHI 200
C A N A +R++ ++I++
Sbjct: 181 CEATNVANSRKTDPVEVQIYV 201
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 160 VDGGNLVIQDARQTDAGRYQCIAR--NAAGTRESAIATLKI-HIKPYLITGPEDVVAQTG 216
VD + + + DA + QC A + S +AT+ + +++ + + P Q G
Sbjct: 66 VDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDVATVHLAYMRKHFLKSPVAQRVQEG 125
Query: 217 SSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275
+++ C+ DP ++ W + G P V DGSL + L+D G Y+CEA
Sbjct: 126 TTLQLPCQAPESDPKAELTWYKD-GVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEAT 184
Query: 276 N 276
N
Sbjct: 185 N 185
Score = 37.9 bits (84), Expect = 0.043
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGS-PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
+ ++ P+ V L C+A S P + WYK GV+V D + I + G + A
Sbjct: 112 HFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDAN-VIRASDGSLIMSA 170
Query: 72 THGRVHSDAGVYWCEATN 89
SD+G Y CEATN
Sbjct: 171 AR---LSDSGNYTCEATN 185
Score = 35.5 bits (78), Expect = 0.23
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 418 PCTAI-CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+ + WY +G + + +DG+L++ SDSG YTC A++
Sbjct: 131 PCQAPESDPKAELTWYKDGVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEATN 185
>AF036698-4|AAB88355.1| 919|Caenorhabditis elegans Uncoordinated
protein 5, isoform a protein.
Length = 919
Score = 66.9 bits (156), Expect = 8e-11
Identities = 55/201 (27%), Positives = 95/201 (47%), Gaps = 19/201 (9%)
Query: 14 IIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL----PAGGLFFL 69
I QP V R++P L CRA + IR YK + D+ L G+ ++
Sbjct: 6 ITTQPKSGYVIRNKPLRLQCRANHATK--IR-YKCSSKWIDDSRIEKLIGTDSTSGVGYI 62
Query: 70 RATH--GRV------HSDAGVYWCEAT--NSYGTARSRNATLHVAVLREEFRLEPESKQS 119
A+ R+ H DA C A+ + S AT+H+A +R+ F P +++
Sbjct: 63 DASVDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDVATVHLAYMRKHFLKSPVAQRV 122
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQ 179
+G T+ L C P P+ + W K+G ++ D+ + G+L++ AR +D+G Y
Sbjct: 123 QEGTTLQLPCQAPESDPKAELTWYKDG--VVVQPDANVIRASDGSLIMSAARLSDSGNYT 180
Query: 180 CIARNAAGTRESAIATLKIHI 200
C A N A +R++ ++I++
Sbjct: 181 CEATNVANSRKTDPVEVQIYV 201
Score = 43.2 bits (97), Expect = 0.001
Identities = 32/121 (26%), Positives = 55/121 (45%), Gaps = 5/121 (4%)
Query: 160 VDGGNLVIQDARQTDAGRYQCIAR--NAAGTRESAIATLKI-HIKPYLITGPEDVVAQTG 216
VD + + + DA + QC A + S +AT+ + +++ + + P Q G
Sbjct: 66 VDISRIDVDTSGHVDAFQCQCYASGDDDQDVVASDVATVHLAYMRKHFLKSPVAQRVQEG 125
Query: 217 SSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAE 275
+++ C+ DP ++ W + G P V DGSL + L+D G Y+CEA
Sbjct: 126 TTLQLPCQAPESDPKAELTWYKD-GVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEAT 184
Query: 276 N 276
N
Sbjct: 185 N 185
Score = 37.9 bits (84), Expect = 0.043
Identities = 26/78 (33%), Positives = 37/78 (47%), Gaps = 5/78 (6%)
Query: 13 YIIEQPLDVTVARHQPATLNCRAGGS-PSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRA 71
+ ++ P+ V L C+A S P + WYK GV+V D + I + G + A
Sbjct: 112 HFLKSPVAQRVQEGTTLQLPCQAPESDPKAELTWYKDGVVVQPDAN-VIRASDGSLIMSA 170
Query: 72 THGRVHSDAGVYWCEATN 89
SD+G Y CEATN
Sbjct: 171 AR---LSDSGNYTCEATN 185
Score = 35.5 bits (78), Expect = 0.23
Identities = 18/55 (32%), Positives = 29/55 (52%), Gaps = 1/55 (1%)
Query: 418 PCTAI-CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASS 471
PC A P+ + WY +G + + +DG+L++ SDSG YTC A++
Sbjct: 131 PCQAPESDPKAELTWYKDGVVVQPDANVIRASDGSLIMSAARLSDSGNYTCEATN 185
>AC024778-2|AAF60566.2| 2325|Caenorhabditis elegans Neuronal igcam
protein 4 protein.
Length = 2325
Score = 65.3 bits (152), Expect = 3e-10
Identities = 58/202 (28%), Positives = 90/202 (44%), Gaps = 17/202 (8%)
Query: 114 PESKQSAQG-DTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQ 172
P+ A G D +++EC GSP PN+ W NG + D + + L + G L I D R+
Sbjct: 464 PKDLTVASGTDRIMMECAAT-GSPPPNIIWLLNGHEIQTD-NVKYDLTNDG-LAIHDIRK 520
Query: 173 TDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPL-- 230
+D G Y C +G+ A A ++++ + GP D + G++V F C V + +
Sbjct: 521 SDEGEYTC---EISGSNVKATANVQVNGDSLIEYGPADQKSLIGTNVEFSCEVAKEYVRK 577
Query: 231 PDVLWRRS----AGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGY 286
V W + GN L R+ GSL + V + GEY C +AS
Sbjct: 578 ASVEWYLNDVLLPVNGNSGL-RISRNRKGSLIIRQVGPDNTGEYRCRVTVDGREENASAM 636
Query: 287 LTVYDPPSINLSPNSVNVESGN 308
L + + P++ P V E N
Sbjct: 637 LQIIEKPAM---PERVRAELHN 655
Score = 62.5 bits (145), Expect = 2e-09
Identities = 53/189 (28%), Positives = 90/189 (47%), Gaps = 16/189 (8%)
Query: 641 ATPIDSKTIKLMWEILNFYYL----EGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITS 696
A P+ + +I + W L + +G I +R +D+ + L S++ + +T
Sbjct: 1165 AEPVSATSISVSWTPLLATHWNGQPKGYLIVYREIDDENWKEVRTPALRSSEHT---VTD 1221
Query: 697 LRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPE 756
LR +T YE + P++S A+T + VP G P NI + + +KW+P
Sbjct: 1222 LRPFTSYEVNVFSENGFGRSLPTDSVKARTYESVPSGSPRNIVVTAEGSKAAIIKWNPVA 1281
Query: 757 LQLQNGIITGYNVVVNWLDVPANKSMVAINTTV----HQATSLI-MTNLTSGVSYSVQIA 811
NG + GY + V VP +S++A T V Q+T + +++L SY V ++
Sbjct: 1282 ELSTNGDVIGYKLRV----VPERESLMADETKVIDIPGQSTLMAKVSDLRPFTSYHVYMS 1337
Query: 812 AETIIGLGP 820
A TI+G GP
Sbjct: 1338 AYTIVGNGP 1346
Score = 59.3 bits (137), Expect = 2e-08
Identities = 61/206 (29%), Positives = 90/206 (43%), Gaps = 18/206 (8%)
Query: 14 IIEQPLDVTVARHQPATL-NCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRAT 72
+I+ P D+TVA + C A GSP P I W G + +D + L GL A
Sbjct: 460 LIKTPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEIQTDNVKYDLTNDGL----AI 515
Query: 73 HGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREE-FRLEPESKQSAQGDTVVLEC-L 130
H SD G Y CE + S + AT +V V + P ++S G V C +
Sbjct: 516 HDIRKSDEGEYTCEISGS-----NVKATANVQVNGDSLIEYGPADQKSLIGTNVEFSCEV 570
Query: 131 PPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG--GNLVIQDARQTDAGRYQCIARNAAGT 188
+ +V W N L +G+S + + G+L+I+ + G Y+C G
Sbjct: 571 AKEYVRKASVEWYLNDVLLPVNGNSGLRISRNRKGSLIIRQVGPDNTGEYRCRV-TVDGR 629
Query: 189 RESAIATLKIHIKPYLITGPEDVVAQ 214
E+A A L+I KP + PE V A+
Sbjct: 630 EENASAMLQIIEKPAM---PERVRAE 652
Score = 51.6 bits (118), Expect = 3e-06
Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 2/134 (1%)
Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTL-DDVPDGPPINIEMFILNTTTVHLK 751
+I LR + EF ++ K GKPS + T+ P P N+ + +V ++
Sbjct: 714 DIEDLRPSSTAEFRVVASNKHGPGKPSLPSYSVTMPQQPPSAAPRNVAASARSPHSVMVQ 773
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
W P+ +L +G + GY VV L ++ + N T A + ++ L + Y +Q+A
Sbjct: 774 WQQPKEELDSGDVLGY-VVRYRLAGYSSLTWNEKNLTTKDARNTLVDELITWREYEIQVA 832
Query: 812 AETIIGLGPFSQKV 825
A GLG FS+ +
Sbjct: 833 AYNKRGLGVFSESI 846
Score = 50.8 bits (116), Expect = 6e-06
Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 12/163 (7%)
Query: 126 VLECLPPRGSPEP-NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRY--QCIA 182
+ +C+ GS + + W NGQ + ++ L+I + G + +C A
Sbjct: 244 IFDCVTSFGSKDDVRIRWFLNGQQISGSEVGMTTTLNNRRLIISNPSSFTRGEHKLECRA 303
Query: 183 RNAAG-TRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG 241
A G T + A + +P L P ++ GSS++ +C V D+ W ++
Sbjct: 304 DAAMGRTSDQKSAYMTFISRPILKDLPNEIQKTVGSSLSLKCSVKKKSSMDIKWYKN--- 360
Query: 242 GNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSAS 284
G + G L +D + D G Y CEA N+ GA AS
Sbjct: 361 -----GLMMTTQRGKLTIDRIKQDDFGLYQCEATNAAGADLAS 398
Score = 50.8 bits (116), Expect = 6e-06
Identities = 35/125 (28%), Positives = 60/125 (48%), Gaps = 4/125 (3%)
Query: 694 ITSLRKYTKYEFFLIPFYKKFEGKPSN-SRVAQTLDDVPDGPPINIEMFILNTTTVHLKW 752
+T LR +T+Y+ LI K G PS SR +TL PD P + ++ T++ + W
Sbjct: 1118 VTGLRPFTQYQLRLIAENVKGRGAPSEPSRSFETLQTNPDTPSQRLFAEPVSATSISVSW 1177
Query: 753 SPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAA 812
+P NG GY +V +D +++ + T +++ +T+L SY V + +
Sbjct: 1178 TPLLATHWNGQPKGYLIVYREID---DENWKEVRTPALRSSEHTVTDLRPFTSYEVNVFS 1234
Query: 813 ETIIG 817
E G
Sbjct: 1235 ENGFG 1239
Score = 46.8 bits (106), Expect = 9e-05
Identities = 41/180 (22%), Positives = 76/180 (42%), Gaps = 9/180 (5%)
Query: 643 PIDSKTIKLMWEIL---NFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRK 699
P+ S +I++ W+ + + + + P+ ++ + + D + + LRK
Sbjct: 1684 PLSSSSIRVKWDAWPKEDSETITSFKVRYVPVASVLSSVSSEEEIMIVDTNECTLNDLRK 1743
Query: 700 YTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQL 759
+T+Y+ + P+ + EGK S R +TL+D P GP + + +V + W P
Sbjct: 1744 FTEYQISVSPYNRAGEGKMSQVR-DKTLEDKP-GPVGILRFSDVLMDSVKVSWDEP--SQ 1799
Query: 760 QNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
NG + GY +VN+ + + L GV+Y + AET G G
Sbjct: 1800 PNGNVIGY--IVNYKGYRMQEEFKNEDQQRTSRNYFDTHGLAEGVTYFFSVWAETSAGKG 1857
Score = 44.8 bits (101), Expect = 4e-04
Identities = 24/58 (41%), Positives = 31/58 (53%), Gaps = 2/58 (3%)
Query: 419 CTAICTPEPIIAWYFEG-EALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
C A +P P I W G E N + ++TNDG L + D+ KSD G YTC S + K
Sbjct: 480 CAATGSPPPNIIWLLNGHEIQTDNVKYDLTNDG-LAIHDIRKSDEGEYTCEISGSNVK 536
Score = 43.6 bits (98), Expect = 9e-04
Identities = 118/542 (21%), Positives = 201/542 (37%), Gaps = 68/542 (12%)
Query: 298 SPNSVNVESG-NVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
+P + V SG + C ATG P P + W + G+ KY T DG L
Sbjct: 463 TPKDLTVASGTDRIMMECAATGSPPPNIIWLLNGHEI----QTDNVKYDLTN--DG---L 513
Query: 357 TINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAV 416
I+D K+D C +GS+ V+ V + D +I GP++Q I +
Sbjct: 514 AIHDIRKSDE-GEYTCEI---SGSN-VKATANVQVNGDS---LIEYGPADQKSLIGTNVE 565
Query: 417 FPCTAI--CTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
F C + + WY L N N G + ++ + S V G
Sbjct: 566 FSCEVAKEYVRKASVEWYLNDVLLPVNG-----NSGLRISRN--RKGSLIIRQVGPDNTG 618
Query: 475 KYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITHNVTDTSVTLSWSQNNKIGSSS 534
+Y + VD + + ++P + + V + W++ G+
Sbjct: 619 EY--RCRVTVDGREENASAMLQIIEKPAMPERVRAELHNETMPAKVRVRWNEGFD-GNEP 675
Query: 535 ILGYQVEV--------FSRETLSGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFI 586
I+ + +E+ +S T + +N P+ + T ++ L P T F
Sbjct: 676 IIKHAIEMRTMGPTGLWSDWTTAIDNIPKEE------GKPCCWTD--IEDLRPSSTAEFR 727
Query: 587 VRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTEYRNNILTDHIVELIEATPIDS 646
V N HG PS S SVT+ S V+ S ++++ E +DS
Sbjct: 728 VVASNKHGPGKPSLPSYSVTMPQQPPSA-APRNVAASARSPHSVMVQWQQPKEE---LDS 783
Query: 647 KTIKLMWEILNFYYLEGLFIYFRPLDNITIEYEMKTILHSNDVSGFEITSLRKYTKYEFF 706
+ G + +R ++ + K L + D + L + +YE
Sbjct: 784 GDVL------------GYVVRYRLAGYSSLTWNEKN-LTTKDARNTLVDELITWREYEIQ 830
Query: 707 LIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITG 766
+ + K+ G S S T + P P N+ + +LN+T V ++++ PE Q G+ G
Sbjct: 831 VAAYNKRGLGVFSESIEVTTSEGRPTQAPKNVRVKVLNSTAVAIEFTAPEQQRIPGVNLG 890
Query: 767 YNVVVNWLDVPANKSM---VAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQ 823
Y V W P + V ++ Q T+ ++ L Y++ T G GP S
Sbjct: 891 YKVQF-WKGEPEKGELYKQVILDPDRRQLTT-VVNELEKFGHYNLTTLCFTTPGDGPRSN 948
Query: 824 KV 825
V
Sbjct: 949 VV 950
Score = 40.3 bits (90), Expect = 0.008
Identities = 22/82 (26%), Positives = 44/82 (53%), Gaps = 5/82 (6%)
Query: 693 EITSLRKYTKYEFFLIPFYKKFEGKPSNSRVA-QTLDDVPDGPPINIEMFILNTTTVHLK 751
+++ LR +T Y ++ + G +++ ++ +T++DVP PP + + ++ V +K
Sbjct: 1322 KVSDLRPFTSYHVYMSAYTIVGNGPENSTPISFETMEDVP-APPESFQCSYISEQEVRMK 1380
Query: 752 WSPPELQLQNGIITGYNVVVNW 773
W PP NG IT Y ++ W
Sbjct: 1381 WLPP--GSPNGKITNY-IISYW 1399
Score = 38.7 bits (86), Expect = 0.025
Identities = 29/103 (28%), Positives = 41/103 (39%), Gaps = 10/103 (9%)
Query: 85 CEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK 144
C A + G + + + R + P Q G ++ L+C + S ++ W K
Sbjct: 301 CRADAAMGRTSDQKSAYMTFISRPILKDLPNEIQKTVGSSLSLKCSVKKKS-SMDIKWYK 359
Query: 145 NGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
NG M G L I +Q D G YQC A NAAG
Sbjct: 360 NGL---------MMTTQRGKLTIDRIKQDDFGLYQCEATNAAG 393
Score = 36.3 bits (80), Expect = 0.13
Identities = 26/106 (24%), Positives = 45/106 (42%), Gaps = 6/106 (5%)
Query: 725 QTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM-- 782
+TL P PI+++ +V L+W P N GY +++ + P+N++
Sbjct: 1562 RTLPSAPFAQPISLKATPYERNSVQLEWVVPHKSTWNSDAIGYR--IHYREYPSNETWQM 1619
Query: 783 --VAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVY 826
+AI I+ L S Y +++ G GPFS V+
Sbjct: 1620 EEIAIRDEHEDKEEKILAKLDSFKHYILRMRIFNSEGEGPFSAPVF 1665
Score = 35.1 bits (77), Expect = 0.31
Identities = 32/130 (24%), Positives = 52/130 (40%), Gaps = 14/130 (10%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG 64
Y+T P + + P ++ +L C S I+WYK G+++ T R
Sbjct: 317 YMTFISRPILKDLPNEIQKTVGSSLSLKCSVKKKSSMDIKWYKNGLMMT--TQRG----- 369
Query: 65 GLFFLRATHGRV-HSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGD 123
+ T R+ D G+Y CEATN+ G A + + E E + +
Sbjct: 370 -----KLTIDRIKQDDFGLYQCEATNAAG-ADLASVWVKEGEANETVATEMSEDGMSLEE 423
Query: 124 TVVLECLPPR 133
+ +E PPR
Sbjct: 424 EISMETPPPR 433
Score = 33.5 bits (73), Expect = 0.93
Identities = 30/138 (21%), Positives = 60/138 (43%), Gaps = 12/138 (8%)
Query: 690 SGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVH 749
+ F I L+ T+Y ++ +K +G ++ + G P + + ++ TTV
Sbjct: 1015 TNFTIDGLQPSTRYGVDVMASTRKGDGPVEETKFESGVPPELPGRPSMLSIGDISATTVQ 1074
Query: 750 LKWSPPELQLQNGIITGYNVVVNWL--DVPANKSMVA--INTTVHQATSLIMTNLTSGVS 805
L ++P G+ + W+ A+ S+ A N + +A S+ +T L
Sbjct: 1075 LHFTPG--------FDGHTAIRQWVVEGKMADSSVFAHVFNVSAPKARSITVTGLRPFTQ 1126
Query: 806 YSVQIAAETIIGLGPFSQ 823
Y +++ AE + G G S+
Sbjct: 1127 YQLRLIAENVKGRGAPSE 1144
>U67954-6|AAV28344.1| 452|Caenorhabditis elegans
Wrapper/rega-1/klingon homologprotein 1, isoform e
protein.
Length = 452
Score = 61.7 bits (143), Expect = 3e-09
Identities = 49/179 (27%), Positives = 81/179 (45%), Gaps = 26/179 (14%)
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+V+ C G+P+P V W K L D R H G +VI + ++ AG+Y C+A N
Sbjct: 143 LVITCHVKEGNPKPGVVWTKQAAKLPED-IKREH--GGARIVITEVKKHHAGKYNCLAEN 199
Query: 185 AAGTRESAIATLKIHI----------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
AG S AT+ IH+ KP++ + + + +F C G P+P V
Sbjct: 200 IAG---SDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVE 256
Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVI--------LADE--GEYSCEAENSVGAVSA 283
W + N + K + + RL+ +++E G+Y+C N +G+V+A
Sbjct: 257 WLFNGYKINFNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTA 315
Score = 47.2 bits (107), Expect = 7e-05
Identities = 67/308 (21%), Positives = 120/308 (38%), Gaps = 34/308 (11%)
Query: 101 LHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD------ 154
L +A + R + + + +G+++ L C P + W+KN + + D +
Sbjct: 11 LLIASTSAQIRTKGGTLIAKEGESLTLRCEVE--DPSVAIIWRKNTEVVAVDDEILDTYG 68
Query: 155 SRMHLVDGGN--LVIQDARQTDAGRYQC-IARNAAGT----RESAIATLKIHIKPYLITG 207
++G L I+ ++ Y C +A + ++ +KP ++
Sbjct: 69 GYEISMEGSTSVLTIKRVEPINSANYSCALAEPEVSVTFVIKVQVFKPTQVSVKPLVVIS 128
Query: 208 PEDVV--AQTGS-SVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI 263
P+ V A+ G ++ C V G+P P V+W + A +P + + + V
Sbjct: 129 PDTGVYHARVGEKNLVITCHVKEGNPKPGVVWTKQAA--KLPEDIKREHGGARIVITEVK 186
Query: 264 LADEGEYSCEAENSVGAVSASGYLTVYDP--------PSINLSPNSVNVESGNVARFTCT 315
G+Y+C AEN G+ A+ + V +P P + + V A F CT
Sbjct: 187 KHHAGKYNCLAENIAGSDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCT 246
Query: 316 ATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAV-FDGV--TVLTINDTDKNDSRNTIVC 372
G P P + W G + I F K TA +G + LT+ D + ++ C
Sbjct: 247 YDGTPVPQVEWLFNGYK-INFNDEKFKKTSETAQRLNGYSKSTLTVGDISE-EAFGDYAC 304
Query: 373 SAVNYAGS 380
N GS
Sbjct: 305 RISNKLGS 312
Score = 31.1 bits (67), Expect = 5.0
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 10/102 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV------VSDTHRSILPA 63
E P++ + + V ++Q A+ C G+P P + W G + T +
Sbjct: 222 EKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEKFKKTSETAQRL 281
Query: 64 GGLFFLRATHGRVHSDA-GVYWCEATNSYGTARSRNATLHVA 104
G T G + +A G Y C +N G S A +HV+
Sbjct: 282 NGYSKSTLTVGDISEEAFGDYACRISNKLG---SVTAVVHVS 320
>U67954-5|AAM54179.1| 444|Caenorhabditis elegans
Wrapper/rega-1/klingon homologprotein 1, isoform b
protein.
Length = 444
Score = 61.7 bits (143), Expect = 3e-09
Identities = 49/179 (27%), Positives = 81/179 (45%), Gaps = 26/179 (14%)
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+V+ C G+P+P V W K L D R H G +VI + ++ AG+Y C+A N
Sbjct: 135 LVITCHVKEGNPKPGVVWTKQAAKLPED-IKREH--GGARIVITEVKKHHAGKYNCLAEN 191
Query: 185 AAGTRESAIATLKIHI----------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
AG S AT+ IH+ KP++ + + + +F C G P+P V
Sbjct: 192 IAG---SDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVE 248
Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVI--------LADE--GEYSCEAENSVGAVSA 283
W + N + K + + RL+ +++E G+Y+C N +G+V+A
Sbjct: 249 WLFNGYKINFNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTA 307
Score = 54.4 bits (125), Expect = 5e-07
Identities = 69/303 (22%), Positives = 120/303 (39%), Gaps = 32/303 (10%)
Query: 101 LHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD------ 154
L +A + R + + + +G+++ L C P + W+KN + + D +
Sbjct: 11 LLIASTSAQIRTKGGTLIAKEGESLTLRCEVE--DPSVAIIWRKNTEVVAVDDEILDTYG 68
Query: 155 SRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV 212
++G L I+ ++ Y C A S +K+ +KP ++ P+ V
Sbjct: 69 GYEISMEGSTSVLTIKRVEPINSANYSCAL---AEPEVSVTFVIKVQVKPLVVISPDTGV 125
Query: 213 --AQTGS-SVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
A+ G ++ C V G+P P V+W + A +P + + + V G
Sbjct: 126 YHARVGEKNLVITCHVKEGNPKPGVVWTKQAA--KLPEDIKREHGGARIVITEVKKHHAG 183
Query: 269 EYSCEAENSVGAVSASGYLTVYDP--------PSINLSPNSVNVESGNVARFTCTATGRP 320
+Y+C AEN G+ A+ + V +P P + + V A F CT G P
Sbjct: 184 KYNCLAENIAGSDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTP 243
Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAV-FDGV--TVLTINDTDKNDSRNTIVCSAVNY 377
P + W G + I F K TA +G + LT+ D + ++ C N
Sbjct: 244 VPQVEWLFNGYK-INFNDEKFKKTSETAQRLNGYSKSTLTVGDISE-EAFGDYACRISNK 301
Query: 378 AGS 380
GS
Sbjct: 302 LGS 304
Score = 31.1 bits (67), Expect = 5.0
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 10/102 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV------VSDTHRSILPA 63
E P++ + + V ++Q A+ C G+P P + W G + T +
Sbjct: 214 EKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEKFKKTSETAQRL 273
Query: 64 GGLFFLRATHGRVHSDA-GVYWCEATNSYGTARSRNATLHVA 104
G T G + +A G Y C +N G S A +HV+
Sbjct: 274 NGYSKSTLTVGDISEEAFGDYACRISNKLG---SVTAVVHVS 312
>AF456363-1|AAL60234.1| 443|Caenorhabditis elegans immunoglobulin
domain-containingprotein WRK-1B protein.
Length = 443
Score = 61.7 bits (143), Expect = 3e-09
Identities = 49/179 (27%), Positives = 81/179 (45%), Gaps = 26/179 (14%)
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+V+ C G+P+P V W K L D R H G +VI + ++ AG+Y C+A N
Sbjct: 134 LVITCHVKEGNPKPGVVWTKQAAKLPED-IKREH--GGARIVITEVKKHHAGKYNCLAEN 190
Query: 185 AAGTRESAIATLKIHI----------KPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVL 234
AG S AT+ IH+ KP++ + + + +F C G P+P V
Sbjct: 191 IAG---SDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVE 247
Query: 235 WRRSAGGGNMPLGRVKVLDDGSLRLDNVI--------LADE--GEYSCEAENSVGAVSA 283
W + N + K + + RL+ +++E G+Y+C N +G+V+A
Sbjct: 248 WLFNGYKINFNDEKFKKTSETAQRLNGYSKSTLTVGDISEEAFGDYACRISNKLGSVTA 306
Score = 54.4 bits (125), Expect = 5e-07
Identities = 69/303 (22%), Positives = 120/303 (39%), Gaps = 32/303 (10%)
Query: 101 LHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD------ 154
L +A + R + + + +G+++ L C P + W+KN + + D +
Sbjct: 10 LLIASTSAQIRTKGGTLIAKEGESLTLRCEVE--DPSVAIIWRKNTEVVAVDDEILDTYG 67
Query: 155 SRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV 212
++G L I+ ++ Y C A S +K+ +KP ++ P+ V
Sbjct: 68 GYEISMEGSTSVLTIKRVEPINSANYSCAL---AEPEVSVTFVIKVQVKPLVVISPDTGV 124
Query: 213 --AQTGS-SVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
A+ G ++ C V G+P P V+W + A +P + + + V G
Sbjct: 125 YHARVGEKNLVITCHVKEGNPKPGVVWTKQAA--KLPEDIKREHGGARIVITEVKKHHAG 182
Query: 269 EYSCEAENSVGAVSASGYLTVYDP--------PSINLSPNSVNVESGNVARFTCTATGRP 320
+Y+C AEN G+ A+ + V +P P + + V A F CT G P
Sbjct: 183 KYNCLAENIAGSDRATIDIHVAEPLQGEREEKPWVKNEDTFIPVRKNQNASFWCTYDGTP 242
Query: 321 EPTMFWSVEGNRTIIFPGMSRDKYHATAV-FDGV--TVLTINDTDKNDSRNTIVCSAVNY 377
P + W G + I F K TA +G + LT+ D + ++ C N
Sbjct: 243 VPQVEWLFNGYK-INFNDEKFKKTSETAQRLNGYSKSTLTVGDISE-EAFGDYACRISNK 300
Query: 378 AGS 380
GS
Sbjct: 301 LGS 303
Score = 31.1 bits (67), Expect = 5.0
Identities = 25/102 (24%), Positives = 41/102 (40%), Gaps = 10/102 (9%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV------VSDTHRSILPA 63
E P++ + + V ++Q A+ C G+P P + W G + T +
Sbjct: 213 EKPWVKNEDTFIPVRKNQNASFWCTYDGTPVPQVEWLFNGYKINFNDEKFKKTSETAQRL 272
Query: 64 GGLFFLRATHGRVHSDA-GVYWCEATNSYGTARSRNATLHVA 104
G T G + +A G Y C +N G S A +HV+
Sbjct: 273 NGYSKSTLTVGDISEEAFGDYACRISNKLG---SVTAVVHVS 311
>U40942-9|AAC47074.6| 703|Caenorhabditis elegans Synaptogenesis
abnormal protein 1 protein.
Length = 703
Score = 61.3 bits (142), Expect = 4e-09
Identities = 54/205 (26%), Positives = 88/205 (42%), Gaps = 22/205 (10%)
Query: 84 WCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
+CEATN GT R + L+VA + K+ +GD C +P P ++W
Sbjct: 335 FCEATNEIGTTRG-SIKLNVA-FGARIMSTSQDKEVNEGDNAFFHCAT-LANPAPAIFWT 391
Query: 144 KNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-P 202
+ GDS + G NL +++ R G Y C A G R+ I + +HI+ P
Sbjct: 392 R--------GDSDEIIGHGENLTLENVRTWQQGNYNCTA-TVEGFRKQ-ILSHYLHIRGP 441
Query: 203 YLITGPEDVVAQTGSSVTFQCRVGGDP-LPDVLWRRSAGGGNMPLGRVKVLD-------D 254
++ ++V A + C + G P +V W + N GR+ V +
Sbjct: 442 PTVSMKDEVSASLDEATEIICEISGRPKTNNVRWTVNGKEINFNNGRITVHQYPKPYGKE 501
Query: 255 GSLRLDNVILADEGEYSCEAENSVG 279
L++ ++ D G Y+C A N +G
Sbjct: 502 SILKIKDLKEEDFGVYNCSANNGLG 526
Score = 52.0 bits (119), Expect = 2e-06
Identities = 50/185 (27%), Positives = 84/185 (45%), Gaps = 28/185 (15%)
Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGG----------GNMPLGRVKVLD 253
++ P+D +A G + CRV P V W + G GN V
Sbjct: 25 IVEAPKDTLAAVGETAILTCRVEHQQGP-VQWMKDDFGLGTDRDKPLPGNKRYRMVGSAA 83
Query: 254 DG--SLRLDNVILADEGEYSC---EAENSVGAVSASGYLTVY---DPPSINLSPNSVNVE 305
+G +L + NV L D+ +++C E++++ VS+ LTV PP I S +S+
Sbjct: 84 NGEYNLEISNVTLFDDDDFACQISESDHAKAVVSSKAKLTVLVRPTPPKIVKSHHSLKAI 143
Query: 306 SGNVARFTC-TATGRPEPTMFWSV----EGNRTIIFPGMSRDKY---HATAVFDGVTVLT 357
+G+ +C + G+P PT+ W++ G + + G SR K+ HA TV+
Sbjct: 144 AGDPITQSCLSRKGKPPPTIGWAIASDEHGKHIVSWLGESRSKFGGIHAKPEISQETVIA 203
Query: 358 -INDT 361
+N+T
Sbjct: 204 HVNET 208
Score = 40.7 bits (91), Expect = 0.006
Identities = 41/173 (23%), Positives = 69/173 (39%), Gaps = 11/173 (6%)
Query: 171 RQTDAGRYQ-CIARNAAGTRESAIATLKIHIK--PYL-ITGPEDVVAQTGSSVTFQCRVG 226
R D +Y CI+++ + + ++K+ ++ P + +T + + S C V
Sbjct: 236 RPEDDHKYLICISQHMTFPNKIEVDSVKLSLRYAPQINLTVASKLPLRENGSALLACNVN 295
Query: 227 GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG-EYSCEAENSVGAVSASG 285
PL +V + S GN L +L + + + D + CEA N +G S
Sbjct: 296 AKPLDNV--KISWYKGNQKLRET----GDTLTFETLKMEDHNRDIFCEATNEIGTTRGSI 349
Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPG 338
L V I + V G+ A F C P P +FW+ + II G
Sbjct: 350 KLNVAFGARIMSTSQDKEVNEGDNAFFHCATLANPAPAIFWTRGDSDEIIGHG 402
>AY714779-1|AAU14146.1| 1338|Caenorhabditis elegans UNC-89 protein.
Length = 1338
Score = 60.9 bits (141), Expect = 5e-09
Identities = 54/215 (25%), Positives = 86/215 (40%), Gaps = 25/215 (11%)
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
T +DD PI T + L A+F C +P P + W F+G+ L N R +
Sbjct: 866 TKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIE 925
Query: 448 NDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLP 504
D L+L D G Y C A + +G S L+ + + S P
Sbjct: 926 QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI-------------SGETPSRP 972
Query: 505 GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564
G P ++ +DT + + W G + + G + R ++G N + W+ ++
Sbjct: 973 GRPEAELS---SDTEIFIQWEAPE--GPTYLEGITYRLEYR--VAGPND--HGDPWITVS 1023
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
++ +VK L P Y F V +N GL PS
Sbjct: 1024 EKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPS 1058
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + DV + ++QPA C SP+P + W G ++ S+ +I + L
Sbjct: 875 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 934
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARS 96
H + D G Y C A N YGT +S
Sbjct: 935 LNHAAPY-DLGEYVCTAINEYGTDKS 959
Score = 33.5 bits (73), Expect = 0.93
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 4/88 (4%)
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILAD 266
DV + F+C V P P V W G RV + D + L L++ D
Sbjct: 884 DVYLRKNQPAIFECAVSASPAPKVTW-DFQGKILESNDRVTIEQDNNVARLILNHAAPYD 942
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPS 294
GEY C A N G +S L + PS
Sbjct: 943 LGEYVCTAINEYGTDKSSCRLISGETPS 970
Score = 33.5 bits (73), Expect = 0.93
Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIA 182
+ EC SP P V W G+ L + + R+ + N L++ A D G Y C A
Sbjct: 894 IFECAVS-ASPAPKVTWDFQGKIL--ESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTA 950
Query: 183 RNAAGTRESA 192
N GT +S+
Sbjct: 951 INEYGTDKSS 960
>AF003131-8|AAP68959.1| 1393|Caenorhabditis elegans Uncoordinated
protein 89, isoform c protein.
Length = 1393
Score = 60.9 bits (141), Expect = 5e-09
Identities = 54/215 (25%), Positives = 86/215 (40%), Gaps = 25/215 (11%)
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
T +DD PI T + L A+F C +P P + W F+G+ L N R +
Sbjct: 830 TKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIE 889
Query: 448 NDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLP 504
D L+L D G Y C A + +G S L+ + + S P
Sbjct: 890 QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI-------------SGETPSRP 936
Query: 505 GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564
G P ++ +DT + + W G + + G + R ++G N + W+ ++
Sbjct: 937 GRPEAELS---SDTEIFIQWEAPE--GPTYLEGITYRLEYR--VAGPND--HGDPWITVS 987
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
++ +VK L P Y F V +N GL PS
Sbjct: 988 EKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPS 1022
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + DV + ++QPA C SP+P + W G ++ S+ +I + L
Sbjct: 839 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 898
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARS 96
H + D G Y C A N YGT +S
Sbjct: 899 LNHAAPY-DLGEYVCTAINEYGTDKS 923
Score = 33.5 bits (73), Expect = 0.93
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 4/88 (4%)
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILAD 266
DV + F+C V P P V W G RV + D + L L++ D
Sbjct: 848 DVYLRKNQPAIFECAVSASPAPKVTW-DFQGKILESNDRVTIEQDNNVARLILNHAAPYD 906
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPS 294
GEY C A N G +S L + PS
Sbjct: 907 LGEYVCTAINEYGTDKSSCRLISGETPS 934
Score = 33.5 bits (73), Expect = 0.93
Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIA 182
+ EC SP P V W G+ L + + R+ + N L++ A D G Y C A
Sbjct: 858 IFECAVS-ASPAPKVTWDFQGKIL--ESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTA 914
Query: 183 RNAAGTRESA 192
N GT +S+
Sbjct: 915 INEYGTDKSS 924
>AF003131-7|AAV34798.1| 1396|Caenorhabditis elegans Uncoordinated
protein 89, isoform d protein.
Length = 1396
Score = 60.9 bits (141), Expect = 5e-09
Identities = 54/215 (25%), Positives = 86/215 (40%), Gaps = 25/215 (11%)
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVT 447
T +DD PI T + L A+F C +P P + W F+G+ L N R +
Sbjct: 833 TKKNDDGTFAPIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIE 892
Query: 448 NDGT---LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLP 504
D L+L D G Y C A + +G S L+ + + S P
Sbjct: 893 QDNNVARLILNHAAPYDLGEYVCTAINEYGTDKSSCRLI-------------SGETPSRP 939
Query: 505 GPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564
G P ++ +DT + + W G + + G + R ++G N + W+ ++
Sbjct: 940 GRPEAELS---SDTEIFIQWEAPE--GPTYLEGITYRLEYR--VAGPND--HGDPWITVS 990
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPS 599
++ +VK L P Y F V +N GL PS
Sbjct: 991 EKIDDESVIVKHLSPLGIYQFRVTAQNGFGLGLPS 1025
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/86 (31%), Positives = 40/86 (46%), Gaps = 1/86 (1%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP + DV + ++QPA C SP+P + W G ++ S+ +I + L
Sbjct: 842 APIFTARLRDVYLRKNQPAIFECAVSASPAPKVTWDFQGKILESNDRVTIEQDNNVARLI 901
Query: 71 ATHGRVHSDAGVYWCEATNSYGTARS 96
H + D G Y C A N YGT +S
Sbjct: 902 LNHAAPY-DLGEYVCTAINEYGTDKS 926
Score = 33.5 bits (73), Expect = 0.93
Identities = 27/88 (30%), Positives = 35/88 (39%), Gaps = 4/88 (4%)
Query: 210 DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDNVILAD 266
DV + F+C V P P V W G RV + D + L L++ D
Sbjct: 851 DVYLRKNQPAIFECAVSASPAPKVTW-DFQGKILESNDRVTIEQDNNVARLILNHAAPYD 909
Query: 267 EGEYSCEAENSVGAVSASGYLTVYDPPS 294
GEY C A N G +S L + PS
Sbjct: 910 LGEYVCTAINEYGTDKSSCRLISGETPS 937
Score = 33.5 bits (73), Expect = 0.93
Identities = 22/70 (31%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAGRYQCIA 182
+ EC SP P V W G+ L + + R+ + N L++ A D G Y C A
Sbjct: 861 IFECAVS-ASPAPKVTWDFQGKIL--ESNDRVTIEQDNNVARLILNHAAPYDLGEYVCTA 917
Query: 183 RNAAGTRESA 192
N GT +S+
Sbjct: 918 INEYGTDKSS 927
>Z68005-1|CAA91991.1| 1199|Caenorhabditis elegans Hypothetical
protein F59F3.5 protein.
Length = 1199
Score = 58.4 bits (135), Expect = 3e-08
Identities = 49/168 (29%), Positives = 74/168 (44%), Gaps = 15/168 (8%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWK-KNGQTLLFDGDSRMHLV-DGGNLVIQDARQTD---A 175
+GD V L C+ P G+ E +V+WK +N + L + MH V D VI + R
Sbjct: 594 EGDNVRLTCVVPYGAVEFDVFWKFENPKMLKYTTFPAMHPVKDRYKRVILNVRNITIDFT 653
Query: 176 GRYQCIARNAAGTR--ESAIATLKIHIKPYLITGPED--VVAQTGSSVTFQCRVGGDPLP 231
G Y CI +N E++I+ K+ P+L+ + A G C+V G P P
Sbjct: 654 GTYYCIVKNKEFEHRFETSISVEKVS-PPFLLNNNSRSIISASNGQMFDINCKVNGVPTP 712
Query: 232 DVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
D W + P + KV+ + +L + D G + C A N G
Sbjct: 713 DYTWFKD----GYPYTKGKVIGN-ALHVSKAEKRDNGIFWCSATNRAG 755
Score = 38.3 bits (85), Expect = 0.033
Identities = 45/182 (24%), Positives = 67/182 (36%), Gaps = 20/182 (10%)
Query: 299 PNSVNVESGNVARFTCTAT-GRPEPTMFWSVEGNRTI---IFPGMSRDKYHATAVFDGVT 354
P+ + E NV R TC G E +FW E + + FP M K V V
Sbjct: 588 PSDIIFEGDNV-RLTCVVPYGAVEFDVFWKFENPKMLKYTTFPAMHPVKDRYKRVILNVR 646
Query: 355 VLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSM 414
+TI+ T T C N F T S + PP + N S + +
Sbjct: 647 NITIDFT------GTYYCIVKN---KEFEHRFETSISVEKVSPPFLLNNNSRSIISASNG 697
Query: 415 AVFP--CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSR 472
+F C P P W+ +G + + L + +K D+G + C A++R
Sbjct: 698 QMFDINCKVNGVPTPDYTWFKDGYP----YTKGKVIGNALHVSKAEKRDNGIFWCSATNR 753
Query: 473 HG 474
G
Sbjct: 754 AG 755
Score = 38.3 bits (85), Expect = 0.033
Identities = 21/73 (28%), Positives = 33/73 (45%), Gaps = 8/73 (10%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
++ + Q +NC+ G P+P W+K G T ++ G + R D
Sbjct: 692 ISASNGQMFDINCKVNGVPTPDYTWFKDG---YPYTKGKVI--GNALHVSKAEKR---DN 743
Query: 81 GVYWCEATNSYGT 93
G++WC ATN GT
Sbjct: 744 GIFWCSATNRAGT 756
>U42847-4|AAF23186.1| 1073|Caenorhabditis elegans
Immunoglobulin-like cell adhesionmolecule family protein
1 protein.
Length = 1073
Score = 56.4 bits (130), Expect = 1e-07
Identities = 79/351 (22%), Positives = 136/351 (38%), Gaps = 43/351 (12%)
Query: 161 DGGNLVIQDARQTDAGRYQCIARNA------AGTRE---SAIATLKIHIKP---YLITGP 208
+G L I + +G Y C+A N +G+++ + + + KP +++
Sbjct: 375 NGSRLTITSISKAQSGNYTCMATNFLTVYGHSGSQQRMGTGTTIVDVKRKPGQAQIVSAR 434
Query: 209 EDVVAQTGSSVTFQCRV--GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILAD 266
++V G ++ C+ G+P W + GG L + + S + N L+D
Sbjct: 435 QNV--DVGETIKLMCQAEDAGNPSASYTWASPSSGGIFGL---EGHTEKSFEVRNAQLSD 489
Query: 267 EGEYSCEAENSVG-AVSASGYLTVYDPPSINLSPNSVN--VESGNVAR-FTCTATGRPEP 322
G YSC+A N +G + +TV + I+ SP + SG + C A G P P
Sbjct: 490 NGVYSCKAYNDLGEGKIGTVMITVIEKARIS-SPLATERIFTSGEQGKILECEAQGYPSP 548
Query: 323 TMFWSVEG---NRTIIFPGMSRDKYHATAVFDGVTV---LTINDTDKNDSRNTIVCSAVN 376
+ W +G ++I + + F TV LT+ K + C A N
Sbjct: 549 VIKWLKDGRPVKQSIYASSATSESKCLPEDFCTQTVASTLTLAGPLKWSDKGNFTCVADN 608
Query: 377 YAGSSFV-RGKLTVTSDDDRPPPIITNGP--SNQTLPIKSMAVFPCTAICTPEPIIAWYF 433
+ + T+ +P + P S I S A+ C PEP W F
Sbjct: 609 GSDKTDKDSSSWTIVRVLHKPVFLNRKFPEKSLAAADIGSQAIIRCKVSARPEPEFHWMF 668
Query: 434 EGEALIQNHRRNVTNDG----------TLVLKDLDKSDSGTYTCVASSRHG 474
+ +N R + G L ++ + +SD G Y C A++ +G
Sbjct: 669 RDSEISENERHSFHTVGITGKPDEYEQLLQIESVQESDYGEYVCRATNGNG 719
Score = 51.6 bits (118), Expect = 3e-06
Identities = 63/274 (22%), Positives = 102/274 (37%), Gaps = 25/274 (9%)
Query: 63 AGGLFFLRATHGRVHSDAGVYWCEA--TNSYGTARSRNATLHVAVLREEFRLEPESKQSA 120
A G + LR T +S G Y C T+ S AT+ V V + + +S
Sbjct: 97 ATGNYSLRITEVEKNSVEGTYHCNVIGTDDSDVQYSALATVVVLVPPGDPIISTTPSESV 156
Query: 121 -QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQT---DAG 176
+GD + +C+ GSP+P W T+ DG + R T D
Sbjct: 157 IEGDFMTAKCVSVGGSPQPTFTWTLPNDTIASSAIFTTQFRDGATESLLHFRVTSSDDGK 216
Query: 177 RYQCIARNAA----GTRESAIATLKIHIKPYLITGPED----VVAQTGSSVTFQCR-VGG 227
QC N A T++ + L + KP + P + + + G V C
Sbjct: 217 SVQCDVTNRAMLGGETKQVKSSQLNVLYKPVVFVTPTENLTHLSVEEGELVNLTCNSASN 276
Query: 228 DPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P W+ A G G++ +R+D+ + G++ C + N +G +A +
Sbjct: 277 PPAHSYEWKHIASGERYQ-GKI-----WPIRVDSSM---SGDFECRSTNELGEGTAVLKM 327
Query: 288 TVYDPPSINLSPNSVNVESGNVARFTCTATGRPE 321
V P IN+ P S++ C + PE
Sbjct: 328 VVQHIPRINV-PESISPNEMEDIDILCEVSAVPE 360
Score = 46.0 bits (104), Expect = 2e-04
Identities = 63/263 (23%), Positives = 101/263 (38%), Gaps = 32/263 (12%)
Query: 78 SDAGVYWCEATNSYGTARSRNATLHV-AVLREEFRLEPESKQSAQGDTVVLECLPPRGSP 136
SD GVY C+A N G + + V R L E ++ +LEC +G P
Sbjct: 488 SDNGVYSCKAYNDLGEGKIGTVMITVIEKARISSPLATERIFTSGEQGKILEC-EAQGYP 546
Query: 137 EPNVYWKKNG--------------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIA 182
P + W K+G ++ D V + + +D G + C+A
Sbjct: 547 SPVIKWLKDGRPVKQSIYASSATSESKCLPEDFCTQTVASTLTLAGPLKWSDKGNFTCVA 606
Query: 183 RNAAGTRE---SAIATLKIHIKPYLITG--PED--VVAQTGSSVTFQCRVGGDPLPDVLW 235
N + + S+ +++ KP + PE A GS +C+V P P+ W
Sbjct: 607 DNGSDKTDKDSSSWTIVRVLHKPVFLNRKFPEKSLAAADIGSQAIIRCKVSARPEPEFHW 666
Query: 236 --RRSAGGGN-----MPLGRVKVLDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGY 286
R S N +G D+ L++++V +D GEY C A N G
Sbjct: 667 MFRDSEISENERHSFHTVGITGKPDEYEQLLQIESVQESDYGEYVCRATNGNGGDHVVIE 726
Query: 287 LTVYDPPSINLSPNSVNVESGNV 309
L PP++ L ++ S +V
Sbjct: 727 LRKTSPPALPLDLQKLSATSNSV 749
>AY130758-3|AAN61519.1| 10578|Caenorhabditis elegans 1MDa_1 protein
protein.
Length = 10578
Score = 55.6 bits (128), Expect = 2e-07
Identities = 45/177 (25%), Positives = 80/177 (45%), Gaps = 21/177 (11%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ--DARQTDAGRYQCIARNAAGTRES 191
G P+P + W + L+ DG+ + G I+ + + G +C A N AG E+
Sbjct: 3814 GVPQPTISWLIDDHELVSDGERISIKCENGVSAIRFFNVDRNAGGFLKCRATNCAGQVET 3873
Query: 192 A---IATLKIHI----------KPYLITG-PEDVVAQTGSSVTFQCRVGGDPLPDVLWRR 237
+ +A +I + +P+ + PE V +T +C+ G PLP +W +
Sbjct: 3874 SCEIVAADEISVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEK 3933
Query: 238 SAGGGNMPLGRVKV-LDDGS--LRLDNVILADEGEYSCEAENSVGAVSASGYLTVYD 291
G + L + +V +DG+ L++++ L D+ Y+C N G S S + V D
Sbjct: 3934 D--GVLLDLQKYQVTTEDGTSILKIESASLDDKAVYTCTIANEAGCESTSCTIDVVD 3988
Score = 50.4 bits (115), Expect = 8e-06
Identities = 71/285 (24%), Positives = 111/285 (38%), Gaps = 25/285 (8%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+ PY + PL V + TL C G P ++W GV+V D + I G+ L
Sbjct: 4037 QPPYFL-LPLSDKVVIDEKCTLKCVVMGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIALL 4095
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEF-RLEPESKQSAQGDT---- 124
R + + D V CEA N G + V E L+ S + DT
Sbjct: 4096 RMKN--IKKDKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTTT 4153
Query: 125 --VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG-RYQCI 181
L+C+ G+P P+V NG T +S++ D G ++IQ T+ G +C
Sbjct: 4154 DHATLKCIVV-GTPLPDVSCSFNGVT----DNSKIRSED-GIVLIQVNDVTEEGIVVECT 4207
Query: 182 ARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGS-----SVTFQCRVGGDPLPDVLWR 236
N G+ S I + P V Q GS ++ + V P P + W+
Sbjct: 4208 ISNETGSSTSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEPTLFWK 4267
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEG--EYSCEAENSVG 279
+ + +DG + + V +G E++C A+N G
Sbjct: 4268 HNGKSIEEGGDYYLIFEDG-IGILKVFNIQDGSHEFTCIAKNEYG 4311
Score = 49.6 bits (113), Expect = 1e-05
Identities = 85/383 (22%), Positives = 144/383 (37%), Gaps = 36/383 (9%)
Query: 112 LEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
L P S + + L+C+ G P V W +G + D + +H DG L+
Sbjct: 4042 LLPLSDKVVIDEKCTLKCVV-MGIPLVIVKWIVDGVVVTEDDNHEIHFEDGIALLRMKNI 4100
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKIHI---------KPYLITGPEDVVAQTGSSVTFQ 222
+ D QC A N G ++ K + KP + +D T + T +
Sbjct: 4101 KKDKSVVQCEAINCKGKVTTSCVLTKCGVEESEAGDLQKPSFVLSLKDTCTTTDHA-TLK 4159
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG-EYSCEAENSVGAV 281
C V G PLPDV + N + +DG + + + +EG C N G+
Sbjct: 4160 CIVVGTPLPDVSCSFNGVTDNSKIRS----EDGIVLIQVNDVTEEGIVVECTISNETGSS 4215
Query: 282 SASGYLTVYDPPSINLS-PNSVNVESGNV--ARFTCTATG---RPEPTMFWSVEGNRTII 335
+++ + + N P V ++G+V R G PEPT+FW G ++I
Sbjct: 4216 TSNCVVKIIKQEEKNYQRPIIVFNQAGSVNNERELSVKVGVIASPEPTLFWKHNG-KSIE 4274
Query: 336 FPGMSRDKYHATAVF-DGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
G D Y +F DG+ +L + + D + C A N G + V + + +
Sbjct: 4275 EGG---DYY---LIFEDGIGILKVFNI--QDGSHEFTCIAKNEYGQTTVEIPVEIGLKTE 4326
Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
++ N + + A W+ +G+ L + +T D +
Sbjct: 4327 NKLTLVKT--LNDIAVVDDIVQLKIVAEGDLPIEFKWFEDGQILEDDSSHKITVDKCIST 4384
Query: 455 KDLDKSDSGT--YTCVASSRHGK 475
L ++GT TC S+ K
Sbjct: 4385 LQLKLEETGTRIITCEVSNSSSK 4407
Score = 45.6 bits (103), Expect = 2e-04
Identities = 65/264 (24%), Positives = 104/264 (39%), Gaps = 42/264 (15%)
Query: 397 PPIITNGPSNQTLPIKSMA----VFPCTAICTPEPIIAWYFEGEALIQNHRRNV-TNDGT 451
PP+I N T PI A + + P P + GE + + + + N +
Sbjct: 8835 PPVILN---KLTKPITHQAGKSFTYKFNFMGAPAPRLRVLSNGEPVSFDVKYEIYDNIAS 8891
Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGAL-LVDSPINPNIHFFRAADVSSLPGPPTKP 510
L + + K D G YT V +++GK + +VD+P+ P R A + +L
Sbjct: 8892 LYIPKMSKRDGGEYTVVLENKYGKDESDLHITMVDTPLKP-----RKAQLVAL------- 8939
Query: 511 ITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQT 570
TDTS T W + G S IL Y V S E SR W I V +
Sbjct: 8940 -----TDTSATFKWLPPHT-GESDILHYIVMRRSTE----------SRRWRNIGH-VQEK 8982
Query: 571 HYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVS----NSTEY 626
+ L+P Y F + N G PS + + T+ D ++ G + +
Sbjct: 8983 TFTAIELVPNEFYAFRIVAVNGFGEGAPSEIIEVNTLDYDQEESFDFAGEEELKLDDVQV 9042
Query: 627 RNNILTDHIVELIEATPIDSKTIK 650
N ++T+ +E E T + + +K
Sbjct: 9043 NNEVVTEITIEESEVTIEEHRKLK 9066
Score = 45.2 bits (102), Expect = 3e-04
Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 4/104 (3%)
Query: 1 MSDDYVTSGEAP-YIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRS 59
+SD +TS P +++ P VT + T+ C+ G P PA W K GVL+ ++
Sbjct: 3886 ISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSGQPLPAAMWEKDGVLLDLQKYQ- 3944
Query: 60 ILPAGGLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHV 103
+ G L+ + D VY C N G S + T+ V
Sbjct: 3945 VTTEDGTSILKIESASL-DDKAVYTCTIANEAG-CESTSCTIDV 3986
Score = 44.8 bits (101), Expect = 4e-04
Identities = 24/75 (32%), Positives = 38/75 (50%), Gaps = 4/75 (5%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL-DDGS--LRLDNVILADEGEYSC 272
G V +C + G P P++ W G +P ++ +DG LR+++ ++ DEGEY C
Sbjct: 1693 GEPVQLKCLIAGMPQPEIEWTVD-GDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYCC 1751
Query: 273 EAENSVGAVSASGYL 287
A N G + YL
Sbjct: 1752 TASNVAGTTFSKCYL 1766
Score = 43.2 bits (97), Expect = 0.001
Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 1/88 (1%)
Query: 10 EAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFL 69
+AP + + ++ +P L C G P P I W G +V + SI+ G+ L
Sbjct: 1677 QAPKFLRKLVNCFGRIGEPVQLKCLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCIL 1736
Query: 70 RATHGRVHSDAGVYWCEATNSYGTARSR 97
R + D G Y C A+N GT S+
Sbjct: 1737 R-IESTLIEDEGEYCCTASNVAGTTFSK 1763
Score = 43.2 bits (97), Expect = 0.001
Identities = 27/88 (30%), Positives = 43/88 (48%), Gaps = 7/88 (7%)
Query: 307 GNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDS 366
G + C G P+P + W+V+G+ P + D+Y + DGV +L I T D
Sbjct: 1693 GEPVQLKCLIAGMPQPEIEWTVDGD-----PIVPNDEY-SIVYEDGVCILRIESTLIED- 1745
Query: 367 RNTIVCSAVNYAGSSFVRGKLTVTSDDD 394
C+A N AG++F + L ++ DD
Sbjct: 1746 EGEYCCTASNVAGTTFSKCYLKLSEADD 1773
Score = 41.9 bits (94), Expect = 0.003
Identities = 47/233 (20%), Positives = 83/233 (35%), Gaps = 18/233 (7%)
Query: 254 DGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFT 313
D + +VI+A+ G E +++ +Y P S + +
Sbjct: 3750 DSEQIVSDVIVAEVGYDEDECSTIADTITSLSSSPLYTAPVFTERLPSSACFANSKLTLE 3809
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
+G P+PT+ W ++ + + S + + +GV+ + + D+N + + C
Sbjct: 3810 VMFSGVPQPTISWLIDDHELV-----SDGERISIKCENGVSAIRFFNVDRN-AGGFLKCR 3863
Query: 374 AVNYAGSS------FVRGKLTVTSDDD----RPPPIITNGPSNQTLPIKSMAVFPCTAIC 423
A N AG +++V SD P + P T + C
Sbjct: 3864 ATNCAGQVETSCEIVAADEISVISDSSITSSTRPHFVVPLPERVTHTVNDHITIKCKFSG 3923
Query: 424 TPEPIIAWYFEGEALIQNHRRNVTNDGTLVLK--DLDKSDSGTYTCVASSRHG 474
P P W +G L + T DGT +LK D YTC ++ G
Sbjct: 3924 QPLPAAMWEKDGVLLDLQKYQVTTEDGTSILKIESASLDDKAVYTCTIANEAG 3976
Score = 39.9 bits (89), Expect = 0.011
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAGG 65
AP I+E + Q +L C+ +PS A+ W K V V D ++L G
Sbjct: 820 APKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGV 879
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
L DAG+Y C ATN +GTA +
Sbjct: 880 CELLNPEC--FAEDAGLYKCTATNPHGTAET 908
Score = 38.7 bits (86), Expect = 0.025
Identities = 22/68 (32%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLV-IQDARQTDAGRYQC 180
G+ V L+CL G P+P + W +G ++ + + + DG ++ I+ D G Y C
Sbjct: 1693 GEPVQLKCLIA-GMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYCC 1751
Query: 181 IARNAAGT 188
A N AGT
Sbjct: 1752 TASNVAGT 1759
Score = 37.9 bits (84), Expect = 0.043
Identities = 44/186 (23%), Positives = 80/186 (43%), Gaps = 14/186 (7%)
Query: 114 PESKQSAQGDT-VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR- 171
P+S Q ++ V+++C P + W NG LL D M V G V++ +
Sbjct: 8751 PKSHAVGQMNSEVIIKC--KTSQPISDAKWFCNGMVLLPDEQVNM-TVTGCEAVLRLVKF 8807
Query: 172 -QTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITG-PEDVVAQTGSSVTFQCRVGGDP 229
+ G Y + + G++ A L + P ++ + + Q G S T++ G P
Sbjct: 8808 LPQNKGNYHVLIDGSIGSQP---AILSGPVPPVILNKLTKPITHQAGKSFTYKFNFMGAP 8864
Query: 230 LPDVLWRRSAGGGNMPLG-RVKVLDD-GSLRLDNVILADEGEYSCEAENSVGAVSASGYL 287
P + R + G + + ++ D+ SL + + D GEY+ EN G + ++
Sbjct: 8865 APRL--RVLSNGEPVSFDVKYEIYDNIASLYIPKMSKRDGGEYTVVLENKYGKDESDLHI 8922
Query: 288 TVYDPP 293
T+ D P
Sbjct: 8923 TMVDTP 8928
Score = 37.9 bits (84), Expect = 0.043
Identities = 33/106 (31%), Positives = 49/106 (46%), Gaps = 14/106 (13%)
Query: 508 TKPITHNVTDT---SVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIA 564
+KP + VT T +VTL+WS ++ S++ Y VE R+T+ G W A
Sbjct: 10440 SKPTSLQVTSTERETVTLTWSLPTELNGSNVNEYLVE---RKTVDGGR-------W-RHA 10488
Query: 565 RRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDD 610
V + VV L G Y+F V N G S PS ++ T ++
Sbjct: 10489 CTVTDSRAVVDGLFSGTEYVFRVVAVNGAGQSAPSDTIEATTQAEE 10534
Score = 34.7 bits (76), Expect = 0.40
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 7/87 (8%)
Query: 112 LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKK---NGQTLLFDGDSRMHLVDGG--NL 165
+EP S G + L C +P V W K N + + + D ++DGG L
Sbjct: 824 VEPLHSASFLDGQAMSLRC-KITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGVCEL 882
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESA 192
+ + DAG Y+C A N GT E+A
Sbjct: 883 LNPECFAEDAGLYKCTATNPHGTAETA 909
Score = 34.3 bits (75), Expect = 0.53
Identities = 23/72 (31%), Positives = 35/72 (48%), Gaps = 4/72 (5%)
Query: 425 PEPIIAWYFEGEALIQNHRRNVTND-GT--LVLKDLDKSDSGTYTCVASSRHGKYVWSGA 481
P P + WYF E L + ++ + GT ++LK++ K G Y A + HG+ +
Sbjct: 1162 PTPFLEWYFGEEKLQVSQNVSMYYEAGTSAIILKNVQKRQGGNYFLRAHNCHGESILPMK 1221
Query: 482 LLVDSPINPNIH 493
L VD PI H
Sbjct: 1222 LTVD-PIEAVTH 1232
Score = 34.3 bits (75), Expect = 0.53
Identities = 48/218 (22%), Positives = 86/218 (39%), Gaps = 12/218 (5%)
Query: 7 TSGEAPYIIEQPLDVTVAR-HQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGG 65
T G IIE P V + + + C+ S A +W+ G++++ D ++ G
Sbjct: 8740 TIGTGQSIIEHPKSHAVGQMNSEVIIKCKTSQPISDA-KWFCNGMVLLPDEQVNMTVTGC 8798
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTV 125
LR + + G Y S G+ + + V+ + +P + Q+ + T
Sbjct: 8799 EAVLRLVK-FLPQNKGNYHVLIDGSIGSQPAILSGPVPPVILNKL-TKPITHQAGKSFTY 8856
Query: 126 VLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDG-GNLVIQDARQTDAGRYQCIARN 184
+ G+P P + NG+ + F D + + D +L I + D G Y + N
Sbjct: 8857 KFNFM---GAPAPRLRVLSNGEPVSF--DVKYEIYDNIASLYIPKMSKRDGGEYTVVLEN 8911
Query: 185 AAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ 222
G ES + + L +VA T +S TF+
Sbjct: 8912 KYGKDESDLHITMVDTP--LKPRKAQLVALTDTSATFK 8947
Score = 33.9 bits (74), Expect = 0.71
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 135 SPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
S P ++ W N +++L D D R + G N+ + + G Y+C+ RN AG S
Sbjct: 115 SDPPAIFEWFYNEKSVLQDRD-RFQVGHGINISRLKVSRPEQGVYKCVTRNPAGVSTSYG 173
Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTF 221
+ +L + ED+ Q SVT+
Sbjct: 174 YITVNADREHLSSSKEDMRLQRQHSVTY 201
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Query: 429 IAWYFEGEALIQNHRRNVTN--DGT--LVLKDLDKSDSGTYTCVASSRHG 474
++W +G + +N + V DG L ++ DSG YTC A S HG
Sbjct: 976 VSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDSGVYTCTAESEHG 1025
Score = 32.7 bits (71), Expect = 1.6
Identities = 17/59 (28%), Positives = 27/59 (45%), Gaps = 3/59 (5%)
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVT-NDGTLVLKDLDK--SDSGTYTCVASSRHG 474
C P+P I W +G+ ++ N ++ DG +L+ D G Y C AS+ G
Sbjct: 1700 CLIAGMPQPEIEWTVDGDPIVPNDEYSIVYEDGVCILRIESTLIEDEGEYCCTASNVAG 1758
>AF188751-1|AAF00548.1| 1083|Caenorhabditis elegans tyrosine kinase
receptor T17A3.1 protein.
Length = 1083
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/191 (28%), Positives = 84/191 (43%), Gaps = 24/191 (12%)
Query: 100 TLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
T+HVA + +F+L +GDTV L C+ P+ + ++ W ++L +
Sbjct: 555 TVHVADEIPNIKFKLASNKSAIYEGDTVKLTCVVPKLAGRCSITWVHRNLSILHSTEVTE 614
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH--IKPYLI-TGPEDVVAQ 214
H L I++A + +G Y C+ N A S LK+ I PY++ TG A
Sbjct: 615 H-SQLSFLYIRNATTSASGNYTCVLENQASENFSLSTILKVEPIIAPYIVKTG---FSAP 670
Query: 215 TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCE 273
TGS + C + G P P+ W + G G R+K ++ DN G Y C
Sbjct: 671 TGSKL--DCNIDGRPPPEYQWFKD--GTPYGTGRRLKFFEE-----DN-----SGIYQCL 716
Query: 274 AENSVGAVSAS 284
A N G+ + S
Sbjct: 717 ATNRAGSATNS 727
>AF078787-11|AAC26948.2| 1083|Caenorhabditis elegans Vegf (vascular
endothelial growthfactor) receptor family protein 1
protein.
Length = 1083
Score = 55.2 bits (127), Expect = 3e-07
Identities = 54/191 (28%), Positives = 84/191 (43%), Gaps = 24/191 (12%)
Query: 100 TLHVA--VLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM 157
T+HVA + +F+L +GDTV L C+ P+ + ++ W ++L +
Sbjct: 555 TVHVADEIPNIKFKLASNKSAIYEGDTVKLTCVVPKLAGRCSITWVHRNLSILHSTEVTE 614
Query: 158 HLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIH--IKPYLI-TGPEDVVAQ 214
H L I++A + +G Y C+ N A S LK+ I PY++ TG A
Sbjct: 615 H-SQLSFLYIRNATTSASGNYTCVLENQASENFSLSTILKVEPIIAPYIVKTG---FSAP 670
Query: 215 TGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLG-RVKVLDDGSLRLDNVILADEGEYSCE 273
TGS + C + G P P+ W + G G R+K ++ DN G Y C
Sbjct: 671 TGSKL--DCNIDGRPPPEYQWFKD--GTPYGTGRRLKFFEE-----DN-----SGIYQCL 716
Query: 274 AENSVGAVSAS 284
A N G+ + S
Sbjct: 717 ATNRAGSATNS 727
>Z81017-11|CAE47468.1| 1051|Caenorhabditis elegans Hypothetical
protein F58A3.2e protein.
Length = 1051
Score = 54.4 bits (125), Expect = 5e-07
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 34/207 (16%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGR 177
G T+ L C +G PEP + W KNG+ +L +R + +L ++DA D+G
Sbjct: 307 GRTLKLNCRA-KGYPEPQIIWYKNGK-MLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 364
Query: 178 YQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPD 232
+ C A N G+ + + ++ +P +I P + Q+ + TF C+V D LP
Sbjct: 365 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIV-PNILANQSVNINDTATFHCKVVSDLLPH 423
Query: 233 VLWRR-------------SAGGGNMPLGRVKVLD---------DGSLRLDNVILADEGEY 270
++W R SA + D + +L + NV L D+G Y
Sbjct: 424 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIY 483
Query: 271 SCEAENSVGAVSASGYLTVYDPPSINL 297
+C + NS+G A+ LTV + +I+L
Sbjct: 484 ACLSGNSLGMSMANATLTVNEFMAIHL 510
Score = 50.0 bits (114), Expect = 1e-05
Identities = 58/209 (27%), Positives = 84/209 (40%), Gaps = 35/209 (16%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF-----LRATHGRVHSDAGVYWC 85
LNCRA G P P I WYK G ++ + RS GG F V +D+G + C
Sbjct: 312 LNCRAKGYPEPQIIWYKNGKMLKKSSARS----GGYEFKFNRWSLEVEDAVVADSGEFHC 367
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQ-GDTVVLECLPPRGSPEPNVYW 142
EA N G+A+ + V +R + P + QS DT C P++ W
Sbjct: 368 EALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHC-KVVSDLLPHIIW 426
Query: 143 ----KKNG-----------------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
K NG + FD H+ D L I + D G Y C+
Sbjct: 427 VRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACL 486
Query: 182 ARNAAG-TRESAIATLKIHIKPYLITGPE 209
+ N+ G + +A T+ + +L+TG E
Sbjct: 487 SGNSLGMSMANATLTVNEFMAIHLLTGDE 515
Score = 48.4 bits (110), Expect = 3e-05
Identities = 56/249 (22%), Positives = 97/249 (38%), Gaps = 34/249 (13%)
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV------NVESGNVARFTCTATGR 319
+E +YS + A +T +PP + N V + +G + C A G
Sbjct: 260 EEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGY 319
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
PEP + W G ++ +R + F+ + L + D DS C A+N G
Sbjct: 320 PEPQIIWYKNGK--MLKKSSARSGGYEFK-FNRWS-LEVEDAVVADS-GEFHCEALNKVG 374
Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-------- 431
S+ + + + RPP I+ N +NQ++ I A F C + P I W
Sbjct: 375 SAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRINKING 434
Query: 432 ---------------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
Y E + + H +V ++ TL + ++ D G Y C++ + G
Sbjct: 435 SYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACLSGNSLGMS 494
Query: 477 VWSGALLVD 485
+ + L V+
Sbjct: 495 MANATLTVN 503
Score = 45.2 bits (102), Expect = 3e-04
Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 15/186 (8%)
Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY--LITGPEDV 211
+SR ++ ++ + D Q +A +A T + A + K ++ E
Sbjct: 243 ESRTEFINADEKENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETH 302
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKVLDDGSLRLDNVILADE 267
G ++ CR G P P ++W ++ G + SL +++ ++AD
Sbjct: 303 ALPAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADS 362
Query: 268 GEYSCEAENSVGAVSASGYLTVYD----PPSI--NLSPN-SVNVESGNVARFTCTATGRP 320
GE+ CEA N VG+ ++ + + PP I N+ N SVN+ + A F C
Sbjct: 363 GEFHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNI--NDTATFHCKVVSDL 420
Query: 321 EPTMFW 326
P + W
Sbjct: 421 LPHIIW 426
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 216 GSSVTFQCRVGGDPLPD-VLWRRSAGG-GNMPLGRVKVLDDGS---LRLDNVILADEGEY 270
G + F C+ + V W R+ N + + K+ D + L L N+ ++D+G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 271 SCEAENSVGAVSASGYLTVYD 291
SC N+ G +S + + V D
Sbjct: 108 SCRVHNAYGQISRNFTVEVID 128
>Z81017-10|CAD44136.1| 1096|Caenorhabditis elegans Hypothetical
protein F58A3.2d protein.
Length = 1096
Score = 54.4 bits (125), Expect = 5e-07
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 34/207 (16%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGR 177
G T+ L C +G PEP + W KNG+ +L +R + +L ++DA D+G
Sbjct: 307 GRTLKLNCRA-KGYPEPQIIWYKNGK-MLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 364
Query: 178 YQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPD 232
+ C A N G+ + + ++ +P +I P + Q+ + TF C+V D LP
Sbjct: 365 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIV-PNILANQSVNINDTATFHCKVVSDLLPH 423
Query: 233 VLWRR-------------SAGGGNMPLGRVKVLD---------DGSLRLDNVILADEGEY 270
++W R SA + D + +L + NV L D+G Y
Sbjct: 424 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIY 483
Query: 271 SCEAENSVGAVSASGYLTVYDPPSINL 297
+C + NS+G A+ LTV + +I+L
Sbjct: 484 ACLSGNSLGMSMANATLTVNEFMAIHL 510
Score = 50.0 bits (114), Expect = 1e-05
Identities = 58/209 (27%), Positives = 84/209 (40%), Gaps = 35/209 (16%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF-----LRATHGRVHSDAGVYWC 85
LNCRA G P P I WYK G ++ + RS GG F V +D+G + C
Sbjct: 312 LNCRAKGYPEPQIIWYKNGKMLKKSSARS----GGYEFKFNRWSLEVEDAVVADSGEFHC 367
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQ-GDTVVLECLPPRGSPEPNVYW 142
EA N G+A+ + V +R + P + QS DT C P++ W
Sbjct: 368 EALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHC-KVVSDLLPHIIW 426
Query: 143 ----KKNG-----------------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
K NG + FD H+ D L I + D G Y C+
Sbjct: 427 VRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACL 486
Query: 182 ARNAAG-TRESAIATLKIHIKPYLITGPE 209
+ N+ G + +A T+ + +L+TG E
Sbjct: 487 SGNSLGMSMANATLTVNEFMAIHLLTGDE 515
Score = 48.4 bits (110), Expect = 3e-05
Identities = 56/249 (22%), Positives = 97/249 (38%), Gaps = 34/249 (13%)
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV------NVESGNVARFTCTATGR 319
+E +YS + A +T +PP + N V + +G + C A G
Sbjct: 260 EEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGY 319
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
PEP + W G ++ +R + F+ + L + D DS C A+N G
Sbjct: 320 PEPQIIWYKNGK--MLKKSSARSGGYEFK-FNRWS-LEVEDAVVADS-GEFHCEALNKVG 374
Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-------- 431
S+ + + + RPP I+ N +NQ++ I A F C + P I W
Sbjct: 375 SAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRINKING 434
Query: 432 ---------------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
Y E + + H +V ++ TL + ++ D G Y C++ + G
Sbjct: 435 SYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACLSGNSLGMS 494
Query: 477 VWSGALLVD 485
+ + L V+
Sbjct: 495 MANATLTVN 503
Score = 45.2 bits (102), Expect = 3e-04
Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 15/186 (8%)
Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY--LITGPEDV 211
+SR ++ ++ + D Q +A +A T + A + K ++ E
Sbjct: 243 ESRTEFINADEKENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETH 302
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKVLDDGSLRLDNVILADE 267
G ++ CR G P P ++W ++ G + SL +++ ++AD
Sbjct: 303 ALPAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADS 362
Query: 268 GEYSCEAENSVGAVSASGYLTVYD----PPSI--NLSPN-SVNVESGNVARFTCTATGRP 320
GE+ CEA N VG+ ++ + + PP I N+ N SVN+ + A F C
Sbjct: 363 GEFHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNI--NDTATFHCKVVSDL 420
Query: 321 EPTMFW 326
P + W
Sbjct: 421 LPHIIW 426
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 216 GSSVTFQCRVGGDPLPD-VLWRRSAGG-GNMPLGRVKVLDDGS---LRLDNVILADEGEY 270
G + F C+ + V W R+ N + + K+ D + L L N+ ++D+G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 271 SCEAENSVGAVSASGYLTVYD 291
SC N+ G +S + + V D
Sbjct: 108 SCRVHNAYGQISRNFTVEVID 128
>Z81017-9|CAC70095.1| 1128|Caenorhabditis elegans Hypothetical
protein F58A3.2c protein.
Length = 1128
Score = 54.4 bits (125), Expect = 5e-07
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 34/207 (16%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGR 177
G T+ L C +G PEP + W KNG+ +L +R + +L ++DA D+G
Sbjct: 307 GRTLKLNCRA-KGYPEPQIIWYKNGK-MLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 364
Query: 178 YQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPD 232
+ C A N G+ + + ++ +P +I P + Q+ + TF C+V D LP
Sbjct: 365 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIV-PNILANQSVNINDTATFHCKVVSDLLPH 423
Query: 233 VLWRR-------------SAGGGNMPLGRVKVLD---------DGSLRLDNVILADEGEY 270
++W R SA + D + +L + NV L D+G Y
Sbjct: 424 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIY 483
Query: 271 SCEAENSVGAVSASGYLTVYDPPSINL 297
+C + NS+G A+ LTV + +I+L
Sbjct: 484 ACLSGNSLGMSMANATLTVNEFMAIHL 510
Score = 50.0 bits (114), Expect = 1e-05
Identities = 58/209 (27%), Positives = 84/209 (40%), Gaps = 35/209 (16%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF-----LRATHGRVHSDAGVYWC 85
LNCRA G P P I WYK G ++ + RS GG F V +D+G + C
Sbjct: 312 LNCRAKGYPEPQIIWYKNGKMLKKSSARS----GGYEFKFNRWSLEVEDAVVADSGEFHC 367
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQ-GDTVVLECLPPRGSPEPNVYW 142
EA N G+A+ + V +R + P + QS DT C P++ W
Sbjct: 368 EALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHC-KVVSDLLPHIIW 426
Query: 143 ----KKNG-----------------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
K NG + FD H+ D L I + D G Y C+
Sbjct: 427 VRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACL 486
Query: 182 ARNAAG-TRESAIATLKIHIKPYLITGPE 209
+ N+ G + +A T+ + +L+TG E
Sbjct: 487 SGNSLGMSMANATLTVNEFMAIHLLTGDE 515
Score = 48.4 bits (110), Expect = 3e-05
Identities = 56/249 (22%), Positives = 97/249 (38%), Gaps = 34/249 (13%)
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV------NVESGNVARFTCTATGR 319
+E +YS + A +T +PP + N V + +G + C A G
Sbjct: 260 EEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGY 319
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
PEP + W G ++ +R + F+ + L + D DS C A+N G
Sbjct: 320 PEPQIIWYKNGK--MLKKSSARSGGYEFK-FNRWS-LEVEDAVVADS-GEFHCEALNKVG 374
Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-------- 431
S+ + + + RPP I+ N +NQ++ I A F C + P I W
Sbjct: 375 SAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRINKING 434
Query: 432 ---------------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
Y E + + H +V ++ TL + ++ D G Y C++ + G
Sbjct: 435 SYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACLSGNSLGMS 494
Query: 477 VWSGALLVD 485
+ + L V+
Sbjct: 495 MANATLTVN 503
Score = 45.2 bits (102), Expect = 3e-04
Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 15/186 (8%)
Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY--LITGPEDV 211
+SR ++ ++ + D Q +A +A T + A + K ++ E
Sbjct: 243 ESRTEFINADEKENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETH 302
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKVLDDGSLRLDNVILADE 267
G ++ CR G P P ++W ++ G + SL +++ ++AD
Sbjct: 303 ALPAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADS 362
Query: 268 GEYSCEAENSVGAVSASGYLTVYD----PPSI--NLSPN-SVNVESGNVARFTCTATGRP 320
GE+ CEA N VG+ ++ + + PP I N+ N SVN+ + A F C
Sbjct: 363 GEFHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNI--NDTATFHCKVVSDL 420
Query: 321 EPTMFW 326
P + W
Sbjct: 421 LPHIIW 426
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 216 GSSVTFQCRVGGDPLPD-VLWRRSAGG-GNMPLGRVKVLDDGS---LRLDNVILADEGEY 270
G + F C+ + V W R+ N + + K+ D + L L N+ ++D+G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 271 SCEAENSVGAVSASGYLTVYD 291
SC N+ G +S + + V D
Sbjct: 108 SCRVHNAYGQISRNFTVEVID 128
>Z81017-8|CAC70094.2| 988|Caenorhabditis elegans Hypothetical
protein F58A3.2b protein.
Length = 988
Score = 54.4 bits (125), Expect = 5e-07
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 34/207 (16%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGR 177
G T+ L C +G PEP + W KNG+ +L +R + +L ++DA D+G
Sbjct: 255 GRTLKLNCRA-KGYPEPQIIWYKNGK-MLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 312
Query: 178 YQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPD 232
+ C A N G+ + + ++ +P +I P + Q+ + TF C+V D LP
Sbjct: 313 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIV-PNILANQSVNINDTATFHCKVVSDLLPH 371
Query: 233 VLWRR-------------SAGGGNMPLGRVKVLD---------DGSLRLDNVILADEGEY 270
++W R SA + D + +L + NV L D+G Y
Sbjct: 372 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIY 431
Query: 271 SCEAENSVGAVSASGYLTVYDPPSINL 297
+C + NS+G A+ LTV + +I+L
Sbjct: 432 ACLSGNSLGMSMANATLTVNEFMAIHL 458
Score = 50.0 bits (114), Expect = 1e-05
Identities = 58/209 (27%), Positives = 84/209 (40%), Gaps = 35/209 (16%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF-----LRATHGRVHSDAGVYWC 85
LNCRA G P P I WYK G ++ + RS GG F V +D+G + C
Sbjct: 260 LNCRAKGYPEPQIIWYKNGKMLKKSSARS----GGYEFKFNRWSLEVEDAVVADSGEFHC 315
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQ-GDTVVLECLPPRGSPEPNVYW 142
EA N G+A+ + V +R + P + QS DT C P++ W
Sbjct: 316 EALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHC-KVVSDLLPHIIW 374
Query: 143 ----KKNG-----------------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
K NG + FD H+ D L I + D G Y C+
Sbjct: 375 VRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACL 434
Query: 182 ARNAAG-TRESAIATLKIHIKPYLITGPE 209
+ N+ G + +A T+ + +L+TG E
Sbjct: 435 SGNSLGMSMANATLTVNEFMAIHLLTGDE 463
Score = 48.4 bits (110), Expect = 3e-05
Identities = 56/249 (22%), Positives = 97/249 (38%), Gaps = 34/249 (13%)
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV------NVESGNVARFTCTATGR 319
+E +YS + A +T +PP + N V + +G + C A G
Sbjct: 208 EEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGY 267
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
PEP + W G ++ +R + F+ + L + D DS C A+N G
Sbjct: 268 PEPQIIWYKNGK--MLKKSSARSGGYEFK-FNRWS-LEVEDAVVADS-GEFHCEALNKVG 322
Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-------- 431
S+ + + + RPP I+ N +NQ++ I A F C + P I W
Sbjct: 323 SAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRINKING 382
Query: 432 ---------------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
Y E + + H +V ++ TL + ++ D G Y C++ + G
Sbjct: 383 SYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACLSGNSLGMS 442
Query: 477 VWSGALLVD 485
+ + L V+
Sbjct: 443 MANATLTVN 451
Score = 44.8 bits (101), Expect = 4e-04
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 13/122 (10%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
G ++ CR G P P ++W ++ G + SL +++ ++AD GE+
Sbjct: 255 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFH 314
Query: 272 CEAENSVGAVSASGYLTVYD----PPSI--NLSPN-SVNVESGNVARFTCTATGRPEPTM 324
CEA N VG+ ++ + + PP I N+ N SVN+ + A F C P +
Sbjct: 315 CEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNI--NDTATFHCKVVSDLLPHI 372
Query: 325 FW 326
W
Sbjct: 373 IW 374
Score = 39.1 bits (87), Expect = 0.019
Identities = 64/279 (22%), Positives = 113/279 (40%), Gaps = 24/279 (8%)
Query: 216 GSSVTFQCRVGGDPLPD-VLWRRSAGG-GNMPLGRVKVLDDGS---LRLDNVILADEGEY 270
G + F C+ + V W R+ N + + K+ D + L L N+ ++D+G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 271 SCEAENSVGAVSASGYLTVYDPPSIN--LSPNSVNVESGNVARFTCTATGRPEPTMF--W 326
SC N+ G +S + + V DP + L+ + V S + + A R + W
Sbjct: 108 SCRVHNAYGQISRNFTVEVIDPLKLFDWLTEHRVFDISHLLPKLLPPAEMRRVKSQLGGW 167
Query: 327 SVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY-AGSSFVRG 385
N I +R + + IN +K + + +V+
Sbjct: 168 EKMNNEQKIV--RARHILRLRQINHALGTEFINADEKENKEDEEEDYSVSQPVAPDAGLT 225
Query: 386 KLTVTSDDDRPPPIITNGP---SNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQ 440
+L +T+++ PP +N N+T LP C A PEP I WY G+ L +
Sbjct: 226 ELNITAEE--PPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGYPEPQIIWYKNGKMLKK 283
Query: 441 NHRRN-----VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
+ R+ N +L ++D +DSG + C A ++ G
Sbjct: 284 SSARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVG 322
>Z81017-7|CAB02673.2| 1040|Caenorhabditis elegans Hypothetical
protein F58A3.2a protein.
Length = 1040
Score = 54.4 bits (125), Expect = 5e-07
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 34/207 (16%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGR 177
G T+ L C +G PEP + W KNG+ +L +R + +L ++DA D+G
Sbjct: 307 GRTLKLNCRA-KGYPEPQIIWYKNGK-MLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 364
Query: 178 YQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPD 232
+ C A N G+ + + ++ +P +I P + Q+ + TF C+V D LP
Sbjct: 365 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIV-PNILANQSVNINDTATFHCKVVSDLLPH 423
Query: 233 VLWRR-------------SAGGGNMPLGRVKVLD---------DGSLRLDNVILADEGEY 270
++W R SA + D + +L + NV L D+G Y
Sbjct: 424 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIY 483
Query: 271 SCEAENSVGAVSASGYLTVYDPPSINL 297
+C + NS+G A+ LTV + +I+L
Sbjct: 484 ACLSGNSLGMSMANATLTVNEFMAIHL 510
Score = 50.0 bits (114), Expect = 1e-05
Identities = 58/209 (27%), Positives = 84/209 (40%), Gaps = 35/209 (16%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF-----LRATHGRVHSDAGVYWC 85
LNCRA G P P I WYK G ++ + RS GG F V +D+G + C
Sbjct: 312 LNCRAKGYPEPQIIWYKNGKMLKKSSARS----GGYEFKFNRWSLEVEDAVVADSGEFHC 367
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQ-GDTVVLECLPPRGSPEPNVYW 142
EA N G+A+ + V +R + P + QS DT C P++ W
Sbjct: 368 EALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHC-KVVSDLLPHIIW 426
Query: 143 ----KKNG-----------------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
K NG + FD H+ D L I + D G Y C+
Sbjct: 427 VRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACL 486
Query: 182 ARNAAG-TRESAIATLKIHIKPYLITGPE 209
+ N+ G + +A T+ + +L+TG E
Sbjct: 487 SGNSLGMSMANATLTVNEFMAIHLLTGDE 515
Score = 48.4 bits (110), Expect = 3e-05
Identities = 56/249 (22%), Positives = 97/249 (38%), Gaps = 34/249 (13%)
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV------NVESGNVARFTCTATGR 319
+E +YS + A +T +PP + N V + +G + C A G
Sbjct: 260 EEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGY 319
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
PEP + W G ++ +R + F+ + L + D DS C A+N G
Sbjct: 320 PEPQIIWYKNGK--MLKKSSARSGGYEFK-FNRWS-LEVEDAVVADS-GEFHCEALNKVG 374
Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-------- 431
S+ + + + RPP I+ N +NQ++ I A F C + P I W
Sbjct: 375 SAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRINKING 434
Query: 432 ---------------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
Y E + + H +V ++ TL + ++ D G Y C++ + G
Sbjct: 435 SYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACLSGNSLGMS 494
Query: 477 VWSGALLVD 485
+ + L V+
Sbjct: 495 MANATLTVN 503
Score = 45.2 bits (102), Expect = 3e-04
Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 15/186 (8%)
Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY--LITGPEDV 211
+SR ++ ++ + D Q +A +A T + A + K ++ E
Sbjct: 243 ESRTEFINADEKENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETH 302
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKVLDDGSLRLDNVILADE 267
G ++ CR G P P ++W ++ G + SL +++ ++AD
Sbjct: 303 ALPAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADS 362
Query: 268 GEYSCEAENSVGAVSASGYLTVYD----PPSI--NLSPN-SVNVESGNVARFTCTATGRP 320
GE+ CEA N VG+ ++ + + PP I N+ N SVN+ + A F C
Sbjct: 363 GEFHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNI--NDTATFHCKVVSDL 420
Query: 321 EPTMFW 326
P + W
Sbjct: 421 LPHIIW 426
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 216 GSSVTFQCRVGGDPLPD-VLWRRSAGG-GNMPLGRVKVLDDGS---LRLDNVILADEGEY 270
G + F C+ + V W R+ N + + K+ D + L L N+ ++D+G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 271 SCEAENSVGAVSASGYLTVYD 291
SC N+ G +S + + V D
Sbjct: 108 SCRVHNAYGQISRNFTVEVID 128
>U39761-1|AAC46934.1| 1040|Caenorhabditis elegans EGL-15 protein.
Length = 1040
Score = 54.4 bits (125), Expect = 5e-07
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 34/207 (16%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGR 177
G T+ L C +G PEP + W KNG+ +L +R + +L ++DA D+G
Sbjct: 307 GRTLKLNCRA-KGYPEPQIIWYKNGK-MLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 364
Query: 178 YQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPD 232
+ C A N G+ + + ++ +P +I P + Q+ + TF C+V D LP
Sbjct: 365 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIV-PNILANQSVNINDTATFHCKVVSDLLPH 423
Query: 233 VLWRR-------------SAGGGNMPLGRVKVLD---------DGSLRLDNVILADEGEY 270
++W R SA + D + +L + NV L D+G Y
Sbjct: 424 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIY 483
Query: 271 SCEAENSVGAVSASGYLTVYDPPSINL 297
+C + NS+G A+ LTV + +I+L
Sbjct: 484 ACLSGNSLGMSMANATLTVNEFMAIHL 510
Score = 50.0 bits (114), Expect = 1e-05
Identities = 58/209 (27%), Positives = 84/209 (40%), Gaps = 35/209 (16%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF-----LRATHGRVHSDAGVYWC 85
LNCRA G P P I WYK G ++ + RS GG F V +D+G + C
Sbjct: 312 LNCRAKGYPEPQIIWYKNGKMLKKSSARS----GGYEFKFNRWSLEVEDAVVADSGEFHC 367
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQ-GDTVVLECLPPRGSPEPNVYW 142
EA N G+A+ + V +R + P + QS DT C P++ W
Sbjct: 368 EALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHC-KVVSDLLPHIIW 426
Query: 143 ----KKNG-----------------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
K NG + FD H+ D L I + D G Y C+
Sbjct: 427 VRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACL 486
Query: 182 ARNAAG-TRESAIATLKIHIKPYLITGPE 209
+ N+ G + +A T+ + +L+TG E
Sbjct: 487 SGNSLGMSMANATLTVNEFMAIHLLTGDE 515
Score = 48.4 bits (110), Expect = 3e-05
Identities = 56/249 (22%), Positives = 97/249 (38%), Gaps = 34/249 (13%)
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV------NVESGNVARFTCTATGR 319
+E +YS + A +T +PP + N V + +G + C A G
Sbjct: 260 EEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGY 319
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
PEP + W G ++ +R + F+ + L + D DS C A+N G
Sbjct: 320 PEPQIIWYKNGK--MLKKSSARSGGYEFK-FNRWS-LEVEDAVVADS-GEFHCEALNKVG 374
Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-------- 431
S+ + + + RPP I+ N +NQ++ I A F C + P I W
Sbjct: 375 SAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRINKING 434
Query: 432 ---------------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
Y E + + H +V ++ TL + ++ D G Y C++ + G
Sbjct: 435 SYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACLSGNSLGMS 494
Query: 477 VWSGALLVD 485
+ + L V+
Sbjct: 495 MANATLTVN 503
Score = 45.2 bits (102), Expect = 3e-04
Identities = 43/186 (23%), Positives = 77/186 (41%), Gaps = 15/186 (8%)
Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPY--LITGPEDV 211
+SR ++ ++ + D Q +A +A T + A + K ++ E
Sbjct: 243 ESRTEFINADEKENKEDEEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETH 302
Query: 212 VAQTGSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKVLDDGSLRLDNVILADE 267
G ++ CR G P P ++W ++ G + SL +++ ++AD
Sbjct: 303 ALPAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADS 362
Query: 268 GEYSCEAENSVGAVSASGYLTVYD----PPSI--NLSPN-SVNVESGNVARFTCTATGRP 320
GE+ CEA N VG+ ++ + + PP I N+ N SVN+ + A F C
Sbjct: 363 GEFHCEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNI--NDTATFHCKVVSDL 420
Query: 321 EPTMFW 326
P + W
Sbjct: 421 LPHIIW 426
Score = 31.5 bits (68), Expect = 3.8
Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 5/81 (6%)
Query: 216 GSSVTFQCRVGGDPLPD-VLWRRSAGG-GNMPLGRVKVLDDGS---LRLDNVILADEGEY 270
G + F C+ + V W R+ N + + K+ D + L L N+ ++D+G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 271 SCEAENSVGAVSASGYLTVYD 291
SC N+ G +S + + V D
Sbjct: 108 SCRVHNAYGQISRNFTVEVID 128
>AY288941-1|AAP44084.1| 987|Caenorhabditis elegans EGL-15 protein.
Length = 987
Score = 54.4 bits (125), Expect = 5e-07
Identities = 56/207 (27%), Positives = 93/207 (44%), Gaps = 34/207 (16%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRM----HLVDGGNLVIQDARQTDAGR 177
G T+ L C +G PEP + W KNG+ +L +R + +L ++DA D+G
Sbjct: 254 GRTLKLNCRA-KGYPEPQIIWYKNGK-MLKKSSARSGGYEFKFNRWSLEVEDAVVADSGE 311
Query: 178 YQCIARNAAGTRESAIATLKIH--IKPYLITGPEDVVAQT---GSSVTFQCRVGGDPLPD 232
+ C A N G+ + + ++ +P +I P + Q+ + TF C+V D LP
Sbjct: 312 FHCEALNKVGSAKKYFHVIIVNRMRRPPIIV-PNILANQSVNINDTATFHCKVVSDLLPH 370
Query: 233 VLWRR-------------SAGGGNMPLGRVKVLD---------DGSLRLDNVILADEGEY 270
++W R SA + D + +L + NV L D+G Y
Sbjct: 371 IIWVRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIY 430
Query: 271 SCEAENSVGAVSASGYLTVYDPPSINL 297
+C + NS+G A+ LTV + +I+L
Sbjct: 431 ACLSGNSLGMSMANATLTVNEFMAIHL 457
Score = 50.0 bits (114), Expect = 1e-05
Identities = 58/209 (27%), Positives = 84/209 (40%), Gaps = 35/209 (16%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFF-----LRATHGRVHSDAGVYWC 85
LNCRA G P P I WYK G ++ + RS GG F V +D+G + C
Sbjct: 259 LNCRAKGYPEPQIIWYKNGKMLKKSSARS----GGYEFKFNRWSLEVEDAVVADSGEFHC 314
Query: 86 EATNSYGTARSRNATLHVAVLREEFRLEPE--SKQSAQ-GDTVVLECLPPRGSPEPNVYW 142
EA N G+A+ + V +R + P + QS DT C P++ W
Sbjct: 315 EALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHC-KVVSDLLPHIIW 373
Query: 143 ----KKNG-----------------QTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
K NG + FD H+ D L I + D G Y C+
Sbjct: 374 VRINKINGSYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACL 433
Query: 182 ARNAAG-TRESAIATLKIHIKPYLITGPE 209
+ N+ G + +A T+ + +L+TG E
Sbjct: 434 SGNSLGMSMANATLTVNEFMAIHLLTGDE 462
Score = 48.4 bits (110), Expect = 3e-05
Identities = 56/249 (22%), Positives = 97/249 (38%), Gaps = 34/249 (13%)
Query: 266 DEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSV------NVESGNVARFTCTATGR 319
+E +YS + A +T +PP + N V + +G + C A G
Sbjct: 207 EEEDYSVSQPVAPDAGLTELNITAEEPPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGY 266
Query: 320 PEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAG 379
PEP + W G ++ +R + F+ + L + D DS C A+N G
Sbjct: 267 PEPQIIWYKNGK--MLKKSSARSGGYEFK-FNRWS-LEVEDAVVADS-GEFHCEALNKVG 321
Query: 380 SSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAW-------- 431
S+ + + + RPP I+ N +NQ++ I A F C + P I W
Sbjct: 322 SAKKYFHVIIVNRMRRPPIIVPNILANQSVNINDTATFHCKVVSDLLPHIIWVRINKING 381
Query: 432 ---------------YFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGKY 476
Y E + + H +V ++ TL + ++ D G Y C++ + G
Sbjct: 382 SYSYYNNSAEEYMFNYTEMDTFDKAHVHHVGDESTLTIFNVSLDDQGIYACLSGNSLGMS 441
Query: 477 VWSGALLVD 485
+ + L V+
Sbjct: 442 MANATLTVN 450
Score = 44.8 bits (101), Expect = 4e-04
Identities = 33/122 (27%), Positives = 55/122 (45%), Gaps = 13/122 (10%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAG----GGNMPLGRVKVLDDGSLRLDNVILADEGEYS 271
G ++ CR G P P ++W ++ G + SL +++ ++AD GE+
Sbjct: 254 GRTLKLNCRAKGYPEPQIIWYKNGKMLKKSSARSGGYEFKFNRWSLEVEDAVVADSGEFH 313
Query: 272 CEAENSVGAVSASGYLTVYD----PPSI--NLSPN-SVNVESGNVARFTCTATGRPEPTM 324
CEA N VG+ ++ + + PP I N+ N SVN+ + A F C P +
Sbjct: 314 CEALNKVGSAKKYFHVIIVNRMRRPPIIVPNILANQSVNI--NDTATFHCKVVSDLLPHI 371
Query: 325 FW 326
W
Sbjct: 372 IW 373
Score = 40.7 bits (91), Expect = 0.006
Identities = 64/278 (23%), Positives = 113/278 (40%), Gaps = 23/278 (8%)
Query: 216 GSSVTFQCRVGGDPLPD-VLWRRSAGG-GNMPLGRVKVLDDGS---LRLDNVILADEGEY 270
G + F C+ + V W R+ N + + K+ D + L L N+ ++D+G +
Sbjct: 48 GDEIKFDCQTAASKISAFVEWYRNDKLLKNDQIDKDKIRKDNNRMMLHLKNIDVSDQGLW 107
Query: 271 SCEAENSVGAVSASGYLTVYDPPSIN-LSPNSVNVESGNVARFTCTATGRPEPTMF--WS 327
SC N+ G +S + + V DP + L+ + V S + + A R + W
Sbjct: 108 SCRVHNAYGQISRNFTVEVIDPKLFDWLTEHRVFDISHLLPKLLPPAEMRRVKSQLGGWE 167
Query: 328 VEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNY-AGSSFVRGK 386
N I +R + + IN +K + + +V+ +
Sbjct: 168 KMNNEQKIV--RARHILRLRQINHALGTEFINADEKENKEDEEEDYSVSQPVAPDAGLTE 225
Query: 387 LTVTSDDDRPPPIITNGP---SNQT--LPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN 441
L +T+++ PP +N N+T LP C A PEP I WY G+ L ++
Sbjct: 226 LNITAEE--PPYFKSNDNIVLFNETHALPAGRTLKLNCRAKGYPEPQIIWYKNGKMLKKS 283
Query: 442 HRRN-----VTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
R+ N +L ++D +DSG + C A ++ G
Sbjct: 284 SARSGGYEFKFNRWSLEVEDAVVADSGEFHCEALNKVG 321
>AF148954-1|AAD37411.1| 4280|Caenorhabditis elegans myotactin form A
protein.
Length = 4280
Score = 54.4 bits (125), Expect = 5e-07
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 4/118 (3%)
Query: 718 PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
P R +T +DVP GPP N++ + + + KW PE QNG IT Y + LD
Sbjct: 3130 PKTVRTFRTKNDVPTGPPQNLQSTVRKDSELGFKWDAPECIQQNGNITQYEFELVGLDEW 3189
Query: 778 ANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVG 835
+ + T Q T ++ L G Y +++ A T G GP+S + +G
Sbjct: 3190 NEGTREGV--TPRQNT--LIDQLQPGSLYRIKVRAYTAEGPGPWSDSLEIRTTGSELG 3243
Score = 49.2 bits (112), Expect = 2e-05
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 8/112 (7%)
Query: 718 PSNSRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
P +S V T ++ P GPP N+ + ++ + W+ PE + +NG IT Y + +D
Sbjct: 2608 PQSSVVTVTTEEAAPTGPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYELWSMDT 2667
Query: 777 PANKSMVAINTTVHQATS-LIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYF 827
A+ N+T H T L + L Y +++ A G GPFS+ V F
Sbjct: 2668 WAD------NSTGHNPTERLNLDQLIPYTQYQIRVRAINKEGDGPFSEWVPF 2713
Score = 48.0 bits (109), Expect = 4e-05
Identities = 38/136 (27%), Positives = 56/136 (41%), Gaps = 4/136 (2%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
F IT L ++KY + G+ + + QT P G P+ + + T V +
Sbjct: 1360 FTITGLHPHSKYRVGVAAKSNVGAGERVSLEI-QTDQAAPSGAPLYLRTEDIRPTDVSIS 1418
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
W P NG IT Y V D + V T + T + NL Y+V++
Sbjct: 1419 WQAPPCLQTNGEITEYEYEVTAGD---RRQTVQKTTENIRGTRAKIENLQPQTRYNVKVR 1475
Query: 812 AETIIGLGPFSQKVYF 827
A T G GP+S +V F
Sbjct: 1476 AYTARGAGPWSTEVPF 1491
Score = 43.6 bits (98), Expect = 9e-04
Identities = 33/150 (22%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Query: 676 IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP 735
+ + T+ + D+ + IT L Y+ YE + + E P ++ T P PP
Sbjct: 1963 VSRDFVTVYNHKDLD-YTITGLLPYSLYEVRVRA--RTTELGPEETKEVSTEQQPPSSPP 2019
Query: 736 INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795
+N+E ++ +W P + ++G + Y + D A NT+ + T
Sbjct: 2020 LNLESTYALERSLSFQWEPVDCSQRHGHVVNYEYEILGQDDWAKLERQIANTSDLRVT-- 2077
Query: 796 IMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+ LT Y +++ A IG GP ++ +
Sbjct: 2078 -IDGLTPYTKYVMRVKAYNSIGGGPNTENL 2106
Score = 39.5 bits (88), Expect = 0.014
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 7/105 (6%)
Query: 716 GKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV-VVNWL 774
G S+ +A TL +PD P I + ++H++W PP G +T Y V +V+
Sbjct: 2209 GPWSSLVIANTLQVLPDAPRA-IHLIEKTDHSLHIRWVPPIDP--KGYVTQYRVSIVSLD 2265
Query: 775 DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
DV K +N H + + L SY++ I+A T G G
Sbjct: 2266 DVNDKKRTHIVN---HPTLTYLFEELNPETSYNISISAGTKQGFG 2307
Score = 38.7 bits (86), Expect = 0.025
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 639 IEATPIDSKTIKLMWEIL---NFYYLEGLFIYFRPLDNITIEYEMKTIL-HSNDVSGFEI 694
+E T S +I L WE L ++ G + F+ D+ E ++ H S ++I
Sbjct: 2835 LEVTDKTSNSISLKWEGLPQDQATHVVGYVLEFKSEDDNAEWQEYNGVVKHRKTSSDYKI 2894
Query: 695 T--SLRKYTKYEFFLIPFYKKFE-GKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
T L T Y F L K + G+P T P+ PP ++++ L+ T+ +
Sbjct: 2895 TVKQLETATLYFFRLRVVGKNDKRGQPGPETKETTSCGKPEAPPESLKLESLDFETLKIT 2954
Query: 752 WSPPE 756
W+PPE
Sbjct: 2955 WTPPE 2959
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 6/114 (5%)
Query: 735 PINIEMFILNTTTVHLKWSPPEL--QLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQ 791
P ++ + + T +H+ W PPE+ Q +IT + V + D K+ + N TV +
Sbjct: 3462 PTDLHLIEKSDTMLHVDWVPPEIFDPEQRELITHHRVTIAPFDPTTGKTGPSKNYTVPYP 3521
Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNI--DSRSVGLDLLSRYP 843
S+ L Y++ + A T G G Y + R + L LL+R P
Sbjct: 3522 GNSIKFEGLRPETIYNITVQAGTNSGYGHILWGTYSTLAPGQRHI-LRLLNRTP 3574
Score = 32.7 bits (71), Expect = 1.6
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 505 GPPTKPITHNVTDTSVTLSWSQNN-KIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
GPP +VT + ++W+Q + + I Y+ E++S +T + N+T N + +
Sbjct: 2624 GPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYELWSMDTWADNSTGHNPTERLNL 2683
Query: 564 ARRVHQTHYVVK 575
+ + T Y ++
Sbjct: 2684 DQLIPYTQYQIR 2695
Score = 31.1 bits (67), Expect = 5.0
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
G P NI ++ ++ L+W P + I GY +V A++S + A
Sbjct: 438 GVPTNIRSADVDGQSIKLEWDVPRCDETHTPIDGYEYIV----YEASQSAPVDGASYVGA 493
Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+I+ L V Y+ ++ + ++ G +S+ V
Sbjct: 494 PHVIIKGLKQNVDYTFKVRSRSVNGHSQWSKDV 526
>AF148953-1|AAD37410.1| 4450|Caenorhabditis elegans myotactin form B
protein.
Length = 4450
Score = 54.4 bits (125), Expect = 5e-07
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 4/118 (3%)
Query: 718 PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
P R +T +DVP GPP N++ + + + KW PE QNG IT Y + LD
Sbjct: 3130 PKTVRTFRTKNDVPTGPPQNLQSTVRKDSELGFKWDAPECIQQNGNITQYEFELVGLDEW 3189
Query: 778 ANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVG 835
+ + T Q T ++ L G Y +++ A T G GP+S + +G
Sbjct: 3190 NEGTREGV--TPRQNT--LIDQLQPGSLYRIKVRAYTAEGPGPWSDSLEIRTTGSELG 3243
Score = 49.2 bits (112), Expect = 2e-05
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 8/112 (7%)
Query: 718 PSNSRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
P +S V T ++ P GPP N+ + ++ + W+ PE + +NG IT Y + +D
Sbjct: 2608 PQSSVVTVTTEEAAPTGPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYELWSMDT 2667
Query: 777 PANKSMVAINTTVHQATS-LIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYF 827
A+ N+T H T L + L Y +++ A G GPFS+ V F
Sbjct: 2668 WAD------NSTGHNPTERLNLDQLIPYTQYQIRVRAINKEGDGPFSEWVPF 2713
Score = 48.0 bits (109), Expect = 4e-05
Identities = 38/136 (27%), Positives = 56/136 (41%), Gaps = 4/136 (2%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
F IT L ++KY + G+ + + QT P G P+ + + T V +
Sbjct: 1360 FTITGLHPHSKYRVGVAAKSNVGAGERVSLEI-QTDQAAPSGAPLYLRTEDIRPTDVSIS 1418
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
W P NG IT Y V D + V T + T + NL Y+V++
Sbjct: 1419 WQAPPCLQTNGEITEYEYEVTAGD---RRQTVQKTTENIRGTRAKIENLQPQTRYNVKVR 1475
Query: 812 AETIIGLGPFSQKVYF 827
A T G GP+S +V F
Sbjct: 1476 AYTARGAGPWSTEVPF 1491
Score = 43.6 bits (98), Expect = 9e-04
Identities = 33/150 (22%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Query: 676 IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP 735
+ + T+ + D+ + IT L Y+ YE + + E P ++ T P PP
Sbjct: 1963 VSRDFVTVYNHKDLD-YTITGLLPYSLYEVRVRA--RTTELGPEETKEVSTEQQPPSSPP 2019
Query: 736 INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795
+N+E ++ +W P + ++G + Y + D A NT+ + T
Sbjct: 2020 LNLESTYALERSLSFQWEPVDCSQRHGHVVNYEYEILGQDDWAKLERQIANTSDLRVT-- 2077
Query: 796 IMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+ LT Y +++ A IG GP ++ +
Sbjct: 2078 -IDGLTPYTKYVMRVKAYNSIGGGPNTENL 2106
Score = 39.5 bits (88), Expect = 0.014
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 7/105 (6%)
Query: 716 GKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV-VVNWL 774
G S+ +A TL +PD P I + ++H++W PP G +T Y V +V+
Sbjct: 2209 GPWSSLVIANTLQVLPDAPRA-IHLIEKTDHSLHIRWVPPIDP--KGYVTQYRVSIVSLD 2265
Query: 775 DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
DV K +N H + + L SY++ I+A T G G
Sbjct: 2266 DVNDKKRTHIVN---HPTLTYLFEELNPETSYNISISAGTKQGFG 2307
Score = 38.7 bits (86), Expect = 0.025
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 639 IEATPIDSKTIKLMWEIL---NFYYLEGLFIYFRPLDNITIEYEMKTIL-HSNDVSGFEI 694
+E T S +I L WE L ++ G + F+ D+ E ++ H S ++I
Sbjct: 2835 LEVTDKTSNSISLKWEGLPQDQATHVVGYVLEFKSEDDNAEWQEYNGVVKHRKTSSDYKI 2894
Query: 695 T--SLRKYTKYEFFLIPFYKKFE-GKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
T L T Y F L K + G+P T P+ PP ++++ L+ T+ +
Sbjct: 2895 TVKQLETATLYFFRLRVVGKNDKRGQPGPETKETTSCGKPEAPPESLKLESLDFETLKIT 2954
Query: 752 WSPPE 756
W+PPE
Sbjct: 2955 WTPPE 2959
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 6/114 (5%)
Query: 735 PINIEMFILNTTTVHLKWSPPEL--QLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQ 791
P ++ + + T +H+ W PPE+ Q +IT + V + D K+ + N TV +
Sbjct: 3462 PTDLHLIEKSDTMLHVDWVPPEIFDPEQRELITHHRVTIAPFDPTTGKTGPSKNYTVPYP 3521
Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNI--DSRSVGLDLLSRYP 843
S+ L Y++ + A T G G Y + R + L LL+R P
Sbjct: 3522 GNSIKFEGLRPETIYNITVQAGTNSGYGHILWGTYSTLAPGQRHI-LRLLNRTP 3574
Score = 32.7 bits (71), Expect = 1.6
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 505 GPPTKPITHNVTDTSVTLSWSQNN-KIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
GPP +VT + ++W+Q + + I Y+ E++S +T + N+T N + +
Sbjct: 2624 GPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYELWSMDTWADNSTGHNPTERLNL 2683
Query: 564 ARRVHQTHYVVK 575
+ + T Y ++
Sbjct: 2684 DQLIPYTQYQIR 2695
Score = 31.1 bits (67), Expect = 5.0
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
G P NI ++ ++ L+W P + I GY +V A++S + A
Sbjct: 438 GVPTNIRSADVDGQSIKLEWDVPRCDETHTPIDGYEYIV----YEASQSAPVDGASYVGA 493
Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+I+ L V Y+ ++ + ++ G +S+ V
Sbjct: 494 PHVIIKGLKQNVDYTFKVRSRSVNGHSQWSKDV 526
>AF040648-5|AAK21413.1| 4450|Caenorhabditis elegans Lethal protein
805, isoform b protein.
Length = 4450
Score = 54.4 bits (125), Expect = 5e-07
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 4/118 (3%)
Query: 718 PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
P R +T +DVP GPP N++ + + + KW PE QNG IT Y + LD
Sbjct: 3130 PKTVRTFRTKNDVPTGPPQNLQSTVRKDSELGFKWDAPECIQQNGNITQYEFELVGLDEW 3189
Query: 778 ANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVG 835
+ + T Q T ++ L G Y +++ A T G GP+S + +G
Sbjct: 3190 NEGTREGV--TPRQNT--LIDQLQPGSLYRIKVRAYTAEGPGPWSDSLEIRTTGSELG 3243
Score = 49.2 bits (112), Expect = 2e-05
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 8/112 (7%)
Query: 718 PSNSRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
P +S V T ++ P GPP N+ + ++ + W+ PE + +NG IT Y + +D
Sbjct: 2608 PQSSVVTVTTEEAAPTGPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYELWSMDT 2667
Query: 777 PANKSMVAINTTVHQATS-LIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYF 827
A+ N+T H T L + L Y +++ A G GPFS+ V F
Sbjct: 2668 WAD------NSTGHNPTERLNLDQLIPYTQYQIRVRAINKEGDGPFSEWVPF 2713
Score = 48.0 bits (109), Expect = 4e-05
Identities = 38/136 (27%), Positives = 56/136 (41%), Gaps = 4/136 (2%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
F IT L ++KY + G+ + + QT P G P+ + + T V +
Sbjct: 1360 FTITGLHPHSKYRVGVAAKSNVGAGERVSLEI-QTDQAAPSGAPLYLRTEDIRPTDVSIS 1418
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
W P NG IT Y V D + V T + T + NL Y+V++
Sbjct: 1419 WQAPPCLQTNGEITEYEYEVTAGD---RRQTVQKTTENIRGTRAKIENLQPQTRYNVKVR 1475
Query: 812 AETIIGLGPFSQKVYF 827
A T G GP+S +V F
Sbjct: 1476 AYTARGAGPWSTEVPF 1491
Score = 43.6 bits (98), Expect = 9e-04
Identities = 33/150 (22%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Query: 676 IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP 735
+ + T+ + D+ + IT L Y+ YE + + E P ++ T P PP
Sbjct: 1963 VSRDFVTVYNHKDLD-YTITGLLPYSLYEVRVRA--RTTELGPEETKEVSTEQQPPSSPP 2019
Query: 736 INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795
+N+E ++ +W P + ++G + Y + D A NT+ + T
Sbjct: 2020 LNLESTYALERSLSFQWEPVDCSQRHGHVVNYEYEILGQDDWAKLERQIANTSDLRVT-- 2077
Query: 796 IMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+ LT Y +++ A IG GP ++ +
Sbjct: 2078 -IDGLTPYTKYVMRVKAYNSIGGGPNTENL 2106
Score = 39.5 bits (88), Expect = 0.014
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 7/105 (6%)
Query: 716 GKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV-VVNWL 774
G S+ +A TL +PD P I + ++H++W PP G +T Y V +V+
Sbjct: 2209 GPWSSLVIANTLQVLPDAPRA-IHLIEKTDHSLHIRWVPPIDP--KGYVTQYRVSIVSLD 2265
Query: 775 DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
DV K +N H + + L SY++ I+A T G G
Sbjct: 2266 DVNDKKRTHIVN---HPTLTYLFEELNPETSYNISISAGTKQGFG 2307
Score = 38.7 bits (86), Expect = 0.025
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 639 IEATPIDSKTIKLMWEIL---NFYYLEGLFIYFRPLDNITIEYEMKTIL-HSNDVSGFEI 694
+E T S +I L WE L ++ G + F+ D+ E ++ H S ++I
Sbjct: 2835 LEVTDKTSNSISLKWEGLPQDQATHVVGYVLEFKSEDDNAEWQEYNGVVKHRKTSSDYKI 2894
Query: 695 T--SLRKYTKYEFFLIPFYKKFE-GKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
T L T Y F L K + G+P T P+ PP ++++ L+ T+ +
Sbjct: 2895 TVKQLETATLYFFRLRVVGKNDKRGQPGPETKETTSCGKPEAPPESLKLESLDFETLKIT 2954
Query: 752 WSPPE 756
W+PPE
Sbjct: 2955 WTPPE 2959
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 6/114 (5%)
Query: 735 PINIEMFILNTTTVHLKWSPPEL--QLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQ 791
P ++ + + T +H+ W PPE+ Q +IT + V + D K+ + N TV +
Sbjct: 3462 PTDLHLIEKSDTMLHVDWVPPEIFDPEQRELITHHRVTIAPFDPTTGKTGPSKNYTVPYP 3521
Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNI--DSRSVGLDLLSRYP 843
S+ L Y++ + A T G G Y + R + L LL+R P
Sbjct: 3522 GNSIKFEGLRPETIYNITVQAGTNSGYGHILWGTYSTLAPGQRHI-LRLLNRTP 3574
Score = 32.7 bits (71), Expect = 1.6
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 505 GPPTKPITHNVTDTSVTLSWSQNN-KIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
GPP +VT + ++W+Q + + I Y+ E++S +T + N+T N + +
Sbjct: 2624 GPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYELWSMDTWADNSTGHNPTERLNL 2683
Query: 564 ARRVHQTHYVVK 575
+ + T Y ++
Sbjct: 2684 DQLIPYTQYQIR 2695
Score = 31.1 bits (67), Expect = 5.0
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
G P NI ++ ++ L+W P + I GY +V A++S + A
Sbjct: 438 GVPTNIRSADVDGQSIKLEWDVPRCDETHTPIDGYEYIV----YEASQSAPVDGASYVGA 493
Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+I+ L V Y+ ++ + ++ G +S+ V
Sbjct: 494 PHVIIKGLKQNVDYTFKVRSRSVNGHSQWSKDV 526
>AF040648-4|AAK21414.2| 4280|Caenorhabditis elegans Lethal protein
805, isoform a protein.
Length = 4280
Score = 54.4 bits (125), Expect = 5e-07
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 4/118 (3%)
Query: 718 PSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVP 777
P R +T +DVP GPP N++ + + + KW PE QNG IT Y + LD
Sbjct: 3130 PKTVRTFRTKNDVPTGPPQNLQSTVRKDSELGFKWDAPECIQQNGNITQYEFELVGLDEW 3189
Query: 778 ANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNIDSRSVG 835
+ + T Q T ++ L G Y +++ A T G GP+S + +G
Sbjct: 3190 NEGTREGV--TPRQNT--LIDQLQPGSLYRIKVRAYTAEGPGPWSDSLEIRTTGSELG 3243
Score = 49.2 bits (112), Expect = 2e-05
Identities = 34/112 (30%), Positives = 54/112 (48%), Gaps = 8/112 (7%)
Query: 718 PSNSRVAQTLDDV-PDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDV 776
P +S V T ++ P GPP N+ + ++ + W+ PE + +NG IT Y + +D
Sbjct: 2608 PQSSVVTVTTEEAAPTGPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYELWSMDT 2667
Query: 777 PANKSMVAINTTVHQATS-LIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYF 827
A+ N+T H T L + L Y +++ A G GPFS+ V F
Sbjct: 2668 WAD------NSTGHNPTERLNLDQLIPYTQYQIRVRAINKEGDGPFSEWVPF 2713
Score = 48.0 bits (109), Expect = 4e-05
Identities = 38/136 (27%), Positives = 56/136 (41%), Gaps = 4/136 (2%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
F IT L ++KY + G+ + + QT P G P+ + + T V +
Sbjct: 1360 FTITGLHPHSKYRVGVAAKSNVGAGERVSLEI-QTDQAAPSGAPLYLRTEDIRPTDVSIS 1418
Query: 752 WSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIA 811
W P NG IT Y V D + V T + T + NL Y+V++
Sbjct: 1419 WQAPPCLQTNGEITEYEYEVTAGD---RRQTVQKTTENIRGTRAKIENLQPQTRYNVKVR 1475
Query: 812 AETIIGLGPFSQKVYF 827
A T G GP+S +V F
Sbjct: 1476 AYTARGAGPWSTEVPF 1491
Score = 43.6 bits (98), Expect = 9e-04
Identities = 33/150 (22%), Positives = 63/150 (42%), Gaps = 6/150 (4%)
Query: 676 IEYEMKTILHSNDVSGFEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPP 735
+ + T+ + D+ + IT L Y+ YE + + E P ++ T P PP
Sbjct: 1963 VSRDFVTVYNHKDLD-YTITGLLPYSLYEVRVRA--RTTELGPEETKEVSTEQQPPSSPP 2019
Query: 736 INIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSL 795
+N+E ++ +W P + ++G + Y + D A NT+ + T
Sbjct: 2020 LNLESTYALERSLSFQWEPVDCSQRHGHVVNYEYEILGQDDWAKLERQIANTSDLRVT-- 2077
Query: 796 IMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+ LT Y +++ A IG GP ++ +
Sbjct: 2078 -IDGLTPYTKYVMRVKAYNSIGGGPNTENL 2106
Score = 39.5 bits (88), Expect = 0.014
Identities = 31/105 (29%), Positives = 48/105 (45%), Gaps = 7/105 (6%)
Query: 716 GKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNV-VVNWL 774
G S+ +A TL +PD P I + ++H++W PP G +T Y V +V+
Sbjct: 2209 GPWSSLVIANTLQVLPDAPRA-IHLIEKTDHSLHIRWVPPIDP--KGYVTQYRVSIVSLD 2265
Query: 775 DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
DV K +N H + + L SY++ I+A T G G
Sbjct: 2266 DVNDKKRTHIVN---HPTLTYLFEELNPETSYNISISAGTKQGFG 2307
Score = 38.7 bits (86), Expect = 0.025
Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 7/125 (5%)
Query: 639 IEATPIDSKTIKLMWEIL---NFYYLEGLFIYFRPLDNITIEYEMKTIL-HSNDVSGFEI 694
+E T S +I L WE L ++ G + F+ D+ E ++ H S ++I
Sbjct: 2835 LEVTDKTSNSISLKWEGLPQDQATHVVGYVLEFKSEDDNAEWQEYNGVVKHRKTSSDYKI 2894
Query: 695 T--SLRKYTKYEFFLIPFYKKFE-GKPSNSRVAQTLDDVPDGPPINIEMFILNTTTVHLK 751
T L T Y F L K + G+P T P+ PP ++++ L+ T+ +
Sbjct: 2895 TVKQLETATLYFFRLRVVGKNDKRGQPGPETKETTSCGKPEAPPESLKLESLDFETLKIT 2954
Query: 752 WSPPE 756
W+PPE
Sbjct: 2955 WTPPE 2959
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/114 (26%), Positives = 50/114 (43%), Gaps = 6/114 (5%)
Query: 735 PINIEMFILNTTTVHLKWSPPEL--QLQNGIITGYNVVVNWLDVPANKSMVAINTTV-HQ 791
P ++ + + T +H+ W PPE+ Q +IT + V + D K+ + N TV +
Sbjct: 3462 PTDLHLIEKSDTMLHVDWVPPEIFDPEQRELITHHRVTIAPFDPTTGKTGPSKNYTVPYP 3521
Query: 792 ATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNI--DSRSVGLDLLSRYP 843
S+ L Y++ + A T G G Y + R + L LL+R P
Sbjct: 3522 GNSIKFEGLRPETIYNITVQAGTNSGYGHILWGTYSTLAPGQRHI-LRLLNRTP 3574
Score = 32.7 bits (71), Expect = 1.6
Identities = 17/72 (23%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Query: 505 GPPTKPITHNVTDTSVTLSWSQNN-KIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
GPP +VT + ++W+Q + + I Y+ E++S +T + N+T N + +
Sbjct: 2624 GPPQNVRAGSVTSSRADITWTQPECEQRNGKITDYEYELWSMDTWADNSTGHNPTERLNL 2683
Query: 564 ARRVHQTHYVVK 575
+ + T Y ++
Sbjct: 2684 DQLIPYTQYQIR 2695
Score = 31.1 bits (67), Expect = 5.0
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
G P NI ++ ++ L+W P + I GY +V A++S + A
Sbjct: 438 GVPTNIRSADVDGQSIKLEWDVPRCDETHTPIDGYEYIV----YEASQSAPVDGASYVGA 493
Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+I+ L V Y+ ++ + ++ G +S+ V
Sbjct: 494 PHVIIKGLKQNVDYTFKVRSRSVNGHSQWSKDV 526
>U39667-6|AAC69011.2| 640|Caenorhabditis elegans Disorganized
muscle protein 1,isoform a protein.
Length = 640
Score = 53.6 bits (123), Expect = 8e-07
Identities = 71/323 (21%), Positives = 118/323 (36%), Gaps = 41/323 (12%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQP---ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60
D + G+AP+ +QP VAR L C +P+P ++WY V + S
Sbjct: 315 DAMPDGKAPHFPQQP----VARQNDDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSA 370
Query: 61 LPAG----GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116
A + +DAG Y C N +G + F +P+
Sbjct: 371 NLANKGSDSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQI 430
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKK---NGQTLLFDGDSRMHLV---DGGNL----- 165
G +V+E + EP W+K G + R+ V + GN+
Sbjct: 431 SSRDDGQVMVME-FRAKSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSAL 489
Query: 166 -VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGS---- 217
+ + + DAG++ C +N +G + +A T+K + P P+ ++ QT +
Sbjct: 490 EIKEPTKDKDAGQFICTVKNESG-KLTATFTVKFEVPEGAPSFTRKPQ-ILQQTSAGGEP 547
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL--DDGS------LRLDNVILADEGE 269
++ F P V W R+K D+G+ L L N D G
Sbjct: 548 AICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGT 607
Query: 270 YSCEAENSVGAVSASGYLTVYDP 292
Y+C +N G + L + P
Sbjct: 608 YTCNIKNDAGEANVELTLNIEGP 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 71/309 (22%), Positives = 108/309 (34%), Gaps = 29/309 (9%)
Query: 208 PEDVVAQTGS--SVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGS---LR 258
P+ VA+ S+ +C V +P P V W + G D L
Sbjct: 326 PQQPVARQNDDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILT 385
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYL--TVYDPPSINLSPNSVNVESGNVARFTCTA 316
+ + AD G Y C N G +A+ L T + P+ P + + G V A
Sbjct: 386 IKELADADAGAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFRA 445
Query: 317 TGRPEPTMFWS--VEGNRTIIFPGMSRDKYHATAVFDGV--TVLTINDTDKNDSRNTIVC 372
EPT W V G I R K V + L I + K+ +C
Sbjct: 446 KSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFIC 505
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS--NQTLPIKSMAV-FPCTAICTPEPII 429
+ N +G + TV + P T P QT A+ F P +
Sbjct: 506 TVKNESGK--LTATFTVKFEVPEGAPSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQV 563
Query: 430 AWYF-EGEALIQNHR-RNVTND-------GTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
W + + + ++ R + TND L L + DSGTYTC + G+
Sbjct: 564 TWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANVEL 623
Query: 481 ALLVDSPIN 489
L ++ P++
Sbjct: 624 TLNIEGPLD 632
>AY095447-1|AAM23316.1| 640|Caenorhabditis elegans DIM-1(L)
protein.
Length = 640
Score = 53.6 bits (123), Expect = 8e-07
Identities = 71/323 (21%), Positives = 118/323 (36%), Gaps = 41/323 (12%)
Query: 4 DYVTSGEAPYIIEQPLDVTVARHQP---ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60
D + G+AP+ +QP VAR L C +P+P ++WY V + S
Sbjct: 315 DAMPDGKAPHFPQQP----VARQNDDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSA 370
Query: 61 LPAG----GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES 116
A + +DAG Y C N +G + F +P+
Sbjct: 371 NLANKGSDSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQI 430
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKK---NGQTLLFDGDSRMHLV---DGGNL----- 165
G +V+E + EP W+K G + R+ V + GN+
Sbjct: 431 SSRDDGQVMVME-FRAKSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSAL 489
Query: 166 -VIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGS---- 217
+ + + DAG++ C +N +G + +A T+K + P P+ ++ QT +
Sbjct: 490 EIKEPTKDKDAGQFICTVKNESG-KLTATFTVKFEVPEGAPSFTRKPQ-ILQQTSAGGEP 547
Query: 218 SVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVL--DDGS------LRLDNVILADEGE 269
++ F P V W R+K D+G+ L L N D G
Sbjct: 548 AICFDIGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGT 607
Query: 270 YSCEAENSVGAVSASGYLTVYDP 292
Y+C +N G + L + P
Sbjct: 608 YTCNIKNDAGEANVELTLNIEGP 630
Score = 42.3 bits (95), Expect = 0.002
Identities = 71/309 (22%), Positives = 108/309 (34%), Gaps = 29/309 (9%)
Query: 208 PEDVVAQTGS--SVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGS---LR 258
P+ VA+ S+ +C V +P P V W + G D L
Sbjct: 326 PQQPVARQNDDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILT 385
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYL--TVYDPPSINLSPNSVNVESGNVARFTCTA 316
+ + AD G Y C N G +A+ L T + P+ P + + G V A
Sbjct: 386 IKELADADAGAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFRA 445
Query: 317 TGRPEPTMFWS--VEGNRTIIFPGMSRDKYHATAVFDGV--TVLTINDTDKNDSRNTIVC 372
EPT W V G I R K V + L I + K+ +C
Sbjct: 446 KSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFIC 505
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS--NQTLPIKSMAV-FPCTAICTPEPII 429
+ N +G + TV + P T P QT A+ F P +
Sbjct: 506 TVKNESGK--LTATFTVKFEVPEGAPSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQV 563
Query: 430 AWYF-EGEALIQNHR-RNVTND-------GTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
W + + + ++ R + TND L L + DSGTYTC + G+
Sbjct: 564 TWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANVEL 623
Query: 481 ALLVDSPIN 489
L ++ P++
Sbjct: 624 TLNIEGPLD 632
>AF039712-1|AAK21402.2| 239|Caenorhabditis elegans 2 (zwei)
ig-domain protein protein7 protein.
Length = 239
Score = 53.2 bits (122), Expect = 1e-06
Identities = 26/69 (37%), Positives = 40/69 (57%), Gaps = 4/69 (5%)
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176
++ G+ +VLEC P +PEP V W+KNG+ L G+S DG NL++ + G
Sbjct: 152 RRGLHGERMVLEC-PVLANPEPMVRWEKNGEPL---GNSDSIEYDGNNLILNSLTEDHIG 207
Query: 177 RYQCIARNA 185
+Y+CI N+
Sbjct: 208 KYRCIGDNS 216
Score = 40.3 bits (90), Expect = 0.008
Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 13/102 (12%)
Query: 395 RPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLV 453
RPP +I G + L + M V C + PEP++ W GE L + ++ DG L+
Sbjct: 143 RPPHVI--GAERRGLHGERM-VLECPVLANPEPMVRWEKNGEPL--GNSDSIEYDGNNLI 197
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFF 495
L L + G Y C+ + S L VD P P+ +F
Sbjct: 198 LNSLTEDHIGKYRCIGDN-------SFPLFVDGPAIPHQIYF 232
>U39667-7|AAP31442.1| 324|Caenorhabditis elegans Disorganized
muscle protein 1,isoform b protein.
Length = 324
Score = 52.0 bits (119), Expect = 2e-06
Identities = 70/318 (22%), Positives = 116/318 (36%), Gaps = 41/318 (12%)
Query: 9 GEAPYIIEQPLDVTVARHQP---ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG- 64
G+AP+ +QP VAR L C +P+P ++WY V + S A
Sbjct: 4 GKAPHFPQQP----VARQNDDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSANLANK 59
Query: 65 ---GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
+ +DAG Y C N +G + F +P+
Sbjct: 60 GSDSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQISSRDD 119
Query: 122 GDTVVLECLPPRGSPEPNVYWKK---NGQTLLFDGDSRMHLV---DGGNL------VIQD 169
G +V+E + EP W+K G + R+ V + GN+ + +
Sbjct: 120 GQVMVME-FRAKSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEP 178
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGS----SVTFQ 222
+ DAG++ C +N +G + +A T+K + P P+ ++ QT + ++ F
Sbjct: 179 TKDKDAGQFICTVKNESG-KLTATFTVKFEVPEGAPSFTRKPQ-ILQQTSAGGEPAICFD 236
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVL--DDGS------LRLDNVILADEGEYSCEA 274
P V W R+K D+G+ L L N D G Y+C
Sbjct: 237 IGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGTYTCNI 296
Query: 275 ENSVGAVSASGYLTVYDP 292
+N G + L + P
Sbjct: 297 KNDAGEANVELTLNIEGP 314
Score = 42.3 bits (95), Expect = 0.002
Identities = 71/309 (22%), Positives = 108/309 (34%), Gaps = 29/309 (9%)
Query: 208 PEDVVAQTGS--SVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGS---LR 258
P+ VA+ S+ +C V +P P V W + G D L
Sbjct: 10 PQQPVARQNDDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILT 69
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYL--TVYDPPSINLSPNSVNVESGNVARFTCTA 316
+ + AD G Y C N G +A+ L T + P+ P + + G V A
Sbjct: 70 IKELADADAGAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFRA 129
Query: 317 TGRPEPTMFWS--VEGNRTIIFPGMSRDKYHATAVFDGV--TVLTINDTDKNDSRNTIVC 372
EPT W V G I R K V + L I + K+ +C
Sbjct: 130 KSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFIC 189
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS--NQTLPIKSMAV-FPCTAICTPEPII 429
+ N +G + TV + P T P QT A+ F P +
Sbjct: 190 TVKNESGK--LTATFTVKFEVPEGAPSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQV 247
Query: 430 AWYF-EGEALIQNHR-RNVTND-------GTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
W + + + ++ R + TND L L + DSGTYTC + G+
Sbjct: 248 TWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANVEL 307
Query: 481 ALLVDSPIN 489
L ++ P++
Sbjct: 308 TLNIEGPLD 316
>AF500489-1|AAM21705.1| 324|Caenorhabditis elegans DIM-1 short
protein isoform protein.
Length = 324
Score = 52.0 bits (119), Expect = 2e-06
Identities = 70/318 (22%), Positives = 116/318 (36%), Gaps = 41/318 (12%)
Query: 9 GEAPYIIEQPLDVTVARHQP---ATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAG- 64
G+AP+ +QP VAR L C +P+P ++WY V + S A
Sbjct: 4 GKAPHFPQQP----VARQNDDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSANLANK 59
Query: 65 ---GLFFLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQ 121
+ +DAG Y C N +G + F +P+
Sbjct: 60 GSDSYSAILTIKELADADAGAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQISSRDD 119
Query: 122 GDTVVLECLPPRGSPEPNVYWKK---NGQTLLFDGDSRMHLV---DGGNL------VIQD 169
G +V+E + EP W+K G + R+ V + GN+ + +
Sbjct: 120 GQVMVME-FRAKSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEP 178
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIK---PYLITGPEDVVAQTGS----SVTFQ 222
+ DAG++ C +N +G + +A T+K + P P+ ++ QT + ++ F
Sbjct: 179 TKDKDAGQFICTVKNESG-KLTATFTVKFEVPEGAPSFTRKPQ-ILQQTSAGGEPAICFD 236
Query: 223 CRVGGDPLPDVLWRRSAGGGNMPLGRVKVL--DDGS------LRLDNVILADEGEYSCEA 274
P V W R+K D+G+ L L N D G Y+C
Sbjct: 237 IGYSARMNPQVTWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGTYTCNI 296
Query: 275 ENSVGAVSASGYLTVYDP 292
+N G + L + P
Sbjct: 297 KNDAGEANVELTLNIEGP 314
Score = 42.3 bits (95), Expect = 0.002
Identities = 71/309 (22%), Positives = 108/309 (34%), Gaps = 29/309 (9%)
Query: 208 PEDVVAQTGS--SVTFQCRVGGDPLPDVLW----RRSAGGGNMPLGRVKVLDDGS---LR 258
P+ VA+ S+ +C V +P P V W + G D L
Sbjct: 10 PQQPVARQNDDGSLELECFVDANPTPQVKWYYDNKEVENSGRFSANLANKGSDSYSAILT 69
Query: 259 LDNVILADEGEYSCEAENSVGAVSASGYL--TVYDPPSINLSPNSVNVESGNVARFTCTA 316
+ + AD G Y C N G +A+ L T + P+ P + + G V A
Sbjct: 70 IKELADADAGAYRCAIVNPHGKGNANFNLKLTGFSSPTFVEKPQISSRDDGQVMVMEFRA 129
Query: 317 TGRPEPTMFWS--VEGNRTIIFPGMSRDKYHATAVFDGV--TVLTINDTDKNDSRNTIVC 372
EPT W V G I R K V + L I + K+ +C
Sbjct: 130 KSILEPTFVWQKLVGGGAEEIIANSDRIKAVKKLEAGNVYYSALEIKEPTKDKDAGQFIC 189
Query: 373 SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPS--NQTLPIKSMAV-FPCTAICTPEPII 429
+ N +G + TV + P T P QT A+ F P +
Sbjct: 190 TVKNESGK--LTATFTVKFEVPEGAPSFTRKPQILQQTSAGGEPAICFDIGYSARMNPQV 247
Query: 430 AWYF-EGEALIQNHR-RNVTND-------GTLVLKDLDKSDSGTYTCVASSRHGKYVWSG 480
W + + + ++ R + TND L L + DSGTYTC + G+
Sbjct: 248 TWISPKSKKMKESSRIKFKTNDEGNGNFTAQLELTNYKAKDSGTYTCNIKNDAGEANVEL 307
Query: 481 ALLVDSPIN 489
L ++ P++
Sbjct: 308 TLNIEGPLD 316
>U23527-1|AAC46575.2| 1147|Caenorhabditis elegans Neuronal igcam
protein 1, isoform a protein.
Length = 1147
Score = 51.6 bits (118), Expect = 3e-06
Identities = 58/221 (26%), Positives = 89/221 (40%), Gaps = 18/221 (8%)
Query: 399 IITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQNHRRNVTNDGTLVLKDL 457
+I GP+N T+ + A F C + +W L + RR + +L + +
Sbjct: 470 LIIKGPNNITVVVGQTADFQC--LVQRVKARSWMKNNRTLSLFTSRRTIVGSNSLRISKV 527
Query: 458 DKSDSGTYTCVASSRHGKYVWSGALLV----DSPINPNIHFFRA-ADVSSLPGPPTKPIT 512
+ SD G YTCVA S G +S A L S + P + D + +
Sbjct: 528 ELSDEGMYTCVAQSESGHTSYSSAYLTVIDNSSTVAPLVTSTEPFIDKKKDLKIDVEDVR 587
Query: 513 HNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRVHQTHY 572
VT T V + WS KI + + ++ F ET + N + V T
Sbjct: 588 GFVTGTEVRIQWSVLGKIVALT----KISKFLIETQRFGTSEENWIEADTVDSHVRAT-- 641
Query: 573 VVKSLIPGITYMF---IVRTENSHGLSGPSP-VSDSVTVGD 609
+KSLIP Y F ++R + SH LS + ++ T GD
Sbjct: 642 TIKSLIPDNKYKFRIKMIRDDGSHVLSQSTDWMNVETTTGD 682
Score = 50.4 bits (115), Expect = 8e-06
Identities = 30/92 (32%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Query: 204 LITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVI 263
+I GP ++ G + FQC V + W ++ ++ R ++ SLR+ V
Sbjct: 471 IIKGPNNITVVVGQTADFQCLV--QRVKARSWMKNNRTLSLFTSRRTIVGSNSLRISKVE 528
Query: 264 LADEGEYSCEAENSVGAVS-ASGYLTVYDPPS 294
L+DEG Y+C A++ G S +S YLTV D S
Sbjct: 529 LSDEGMYTCVAQSESGHTSYSSAYLTVIDNSS 560
Score = 35.5 bits (78), Expect = 0.23
Identities = 25/78 (32%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTL-LFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
G T +CL R W KN +TL LF SR +V +L I +D G Y C
Sbjct: 483 GQTADFQCLVQRVKARS---WMKNNRTLSLFT--SRRTIVGSNSLRISKVELSDEGMYTC 537
Query: 181 IARNAAGTRESAIATLKI 198
+A++ +G + A L +
Sbjct: 538 VAQSESGHTSYSSAYLTV 555
Score = 31.1 bits (67), Expect = 5.0
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 9/72 (12%)
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQT----LLFDGDSRMHLVDGGNLVIQDARQTDA 175
A+GD VVLEC+ + W K+ T + D SR + GNL I+ D+
Sbjct: 272 AEGDDVVLECVINMA----KIVWIKHNDTTPNVTMDDNTSRFQQI-WGNLKIRSVALGDS 326
Query: 176 GRYQCIARNAAG 187
G Y C+ G
Sbjct: 327 GIYTCLGLPIVG 338
Score = 30.7 bits (66), Expect = 6.6
Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 4/83 (4%)
Query: 759 LQNGIITGYNVVVNWLDVPANKSMVA-INTTVHQATSLIMTNLTSGVSYSVQIAAETIIG 817
++N + +V N + NKS V ++ T T I+T L YS+Q+ AE G
Sbjct: 711 IENAAAKTFVIVYNEVSPDQNKSQVVQVDGT---PTEAIITGLVFDTQYSIQMIAENAAG 767
Query: 818 LGPFSQKVYFNIDSRSVGLDLLS 840
S + FN + + L S
Sbjct: 768 KSLTSAEYLFNTTRKHLTFALTS 790
>Z49938-5|CAD31752.1| 1467|Caenorhabditis elegans Hypothetical
protein C09D8.1b protein.
Length = 1467
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Query: 715 EGKPSNS-RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
EG+ N+ T PDG PI+++ ++ V + W PP + +NG IT Y +++
Sbjct: 227 EGRSQNATETIATPVGSPDGEPIDVQYEVMKGKIV-VSWRPPSEEKRNGNITSYKAILSA 285
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
+D A++ + +S N+ +Y ++AA T+ G+GP+S + N D
Sbjct: 286 MDATADRYEQPV--PAPSTSSTFEVNVRR--AYLFKVAAATMKGIGPYSPVLTINPD 338
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV--H 749
FE+ SL T+Y F L F + +G+ S + T P+ P I + V
Sbjct: 103 FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLDRDEPPVVAR 162
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
++W P+++ I YN+ + P S V T S ++ L GV Y V
Sbjct: 163 IEWKMPKMKPNETPIEKYNLWLRAQGYP--DSYVKAKTVDGTDLSTTISGLWMGVVYDVL 220
Query: 810 IAAE 813
+AAE
Sbjct: 221 LAAE 224
>Z46811-2|CAD31753.1| 1467|Caenorhabditis elegans Hypothetical
protein C09D8.1b protein.
Length = 1467
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Query: 715 EGKPSNS-RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
EG+ N+ T PDG PI+++ ++ V + W PP + +NG IT Y +++
Sbjct: 227 EGRSQNATETIATPVGSPDGEPIDVQYEVMKGKIV-VSWRPPSEEKRNGNITSYKAILSA 285
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
+D A++ + +S N+ +Y ++AA T+ G+GP+S + N D
Sbjct: 286 MDATADRYEQPV--PAPSTSSTFEVNVRR--AYLFKVAAATMKGIGPYSPVLTINPD 338
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV--H 749
FE+ SL T+Y F L F + +G+ S + T P+ P I + V
Sbjct: 103 FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLDRDEPPVVAR 162
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
++W P+++ I YN+ + P S V T S ++ L GV Y V
Sbjct: 163 IEWKMPKMKPNETPIEKYNLWLRAQGYP--DSYVKAKTVDGTDLSTTISGLWMGVVYDVL 220
Query: 810 IAAE 813
+AAE
Sbjct: 221 LAAE 224
>AF316540-1|AAK01633.1| 1487|Caenorhabditis elegans PTP-3B protein.
Length = 1487
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/117 (27%), Positives = 58/117 (49%), Gaps = 6/117 (5%)
Query: 715 EGKPSNS-RVAQTLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNW 773
EG+ N+ T PDG PI+++ ++ V + W PP + +NG IT Y +++
Sbjct: 227 EGRSQNATETIATPVGSPDGEPIDVQYEVMKGKIV-VSWRPPSEEKRNGNITSYKAILSA 285
Query: 774 LDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKVYFNID 830
+D A++ + +S N+ +Y ++AA T+ G+GP+S + N D
Sbjct: 286 MDATADRYEQPV--PAPSTSSTFEVNVRR--AYLFKVAAATMKGIGPYSPVLTINPD 338
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/124 (27%), Positives = 52/124 (41%), Gaps = 4/124 (3%)
Query: 692 FEITSLRKYTKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMFILNTTTV--H 749
FE+ SL T+Y F L F + +G+ S + T P+ P I + V
Sbjct: 103 FELDSLDPNTEYSFRLNAFNRNGDGEFSERKSIITQGIPPEAPEIVSVSLDRDEPPVVAR 162
Query: 750 LKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQ 809
++W P+++ I YN+ + P S V T S ++ L GV Y V
Sbjct: 163 IEWKMPKMKPNETPIEKYNLWLRAQGYP--DSYVKAKTVDGTDLSTTISGLWMGVVYDVL 220
Query: 810 IAAE 813
+AAE
Sbjct: 221 LAAE 224
>AC084152-8|AAK39317.1| 541|Caenorhabditis elegans Hypothetical
protein Y102A11A.8 protein.
Length = 541
Score = 50.4 bits (115), Expect = 8e-06
Identities = 52/229 (22%), Positives = 94/229 (41%), Gaps = 44/229 (19%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG--TRESAIATLK 197
+ W KNG+ L +D ++ D L ++ + D+GRYQC A N G T E +
Sbjct: 68 IQWSKNGEQLDWDSQYKLSK-DSKELKMKSVKFEDSGRYQCQATNGFGHKTIEFIVHVHD 126
Query: 198 IH-----IKPYLI-----TGP-----------EDVVAQTGSSVTFQCRVGGDPLPDVLWR 236
H +K YL+ P + TG + +C G+PLP++ W
Sbjct: 127 QHDKENSVKDYLVLSNTTASPSWLIDMNSEWRSPIKINTGGKLELRCPAQGNPLPEIRWY 186
Query: 237 RSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTV---YDPP 293
++ M + ++ ++ V + G Y C EN +G++S + ++V +DP
Sbjct: 187 QN----EMEISEKTHKHVSTITVEPVESSHSGVYRCVVENPLGSLSFAFDVSVGDFFDPT 242
Query: 294 SINLS-------------PNSVNVESGNVARFTCTATGRPEPTMFWSVE 329
+ + P +++V +G+ A+F C + W E
Sbjct: 243 TTEATEYQETAMEPVIDQPYNISVYAGHTAQFQCKVKSNENTIIKWLKE 291
Score = 33.1 bits (72), Expect = 1.2
Identities = 12/30 (40%), Positives = 18/30 (60%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSI 60
L C A G+P P IRWY+ + + TH+ +
Sbjct: 171 LRCPAQGNPLPEIRWYQNEMEISEKTHKHV 200
Score = 30.3 bits (65), Expect = 8.7
Identities = 15/67 (22%), Positives = 31/67 (46%), Gaps = 6/67 (8%)
Query: 122 GDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCI 181
G + L C P +G+P P + W +N + + H+ + ++ + +G Y+C+
Sbjct: 166 GGKLELRC-PAQGNPLPEIRWYQNEMEI--SEKTHKHV---STITVEPVESSHSGVYRCV 219
Query: 182 ARNAAGT 188
N G+
Sbjct: 220 VENPLGS 226
Score = 30.3 bits (65), Expect = 8.7
Identities = 16/56 (28%), Positives = 27/56 (48%), Gaps = 3/56 (5%)
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHG 474
C A P P I WY + + ++V+ T+ ++ ++ S SG Y CV + G
Sbjct: 173 CPAQGNPLPEIRWYQNEMEISEKTHKHVS---TITVEPVESSHSGVYRCVVENPLG 225
>Z83235-2|CAB05773.2| 265|Caenorhabditis elegans Hypothetical
protein K10C3.3 protein.
Length = 265
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
EF LE +G++V L C P G P+P V W K+ L M +G +++
Sbjct: 135 EFHLESTGTTVEKGESVTLTC-PVTGYPKPVVKWTKDSAPLALSQSVSM---EGSTVIVT 190
Query: 169 DARQTDAGRYQCIARN 184
+A TDAG Y C A N
Sbjct: 191 NANYTDAGTYSCEAVN 206
Score = 40.3 bits (90), Expect = 0.008
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
Query: 2 SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
S ++ T E + TV + + TL C G P P ++W K + +S+
Sbjct: 124 SHEHFTEHEGHEFHLESTGTTVEKGESVTLTCPVTGYPKPVVKWTKDSAPLA--LSQSVS 181
Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSY 91
G + + ++DAG Y CEA N Y
Sbjct: 182 MEGSTVIVTNAN---YTDAGTYSCEAVNEY 208
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273
+ G SVT C V G P P V W + + + L + ++ ++ + N D G YSCE
Sbjct: 146 EKGESVTLTCPVTGYPKPVVKWTKDS--APLALSQSVSMEGSTVIVTNANYTDAGTYSCE 203
Query: 274 AEN 276
A N
Sbjct: 204 AVN 206
Score = 36.7 bits (81), Expect = 0.10
Identities = 31/123 (25%), Positives = 48/123 (39%), Gaps = 23/123 (18%)
Query: 266 DEGEYSCEAENSVGAVSASGYL------------TVYDPPSINLSPNSVNVESGNVARFT 313
D GEY CE + G +S ++ T ++ +L VE G T
Sbjct: 95 DAGEYKCELDTPHGKISHKVFIYSRPVVHSHEHFTEHEGHEFHLESTGTTVEKGESVTLT 154
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
C TG P+P + W+ + + +S +G TV+ N + D+ T C
Sbjct: 155 CPVTGYPKPVVKWTKDSAPLALSQSVS---------MEGSTVIVTN-ANYTDA-GTYSCE 203
Query: 374 AVN 376
AVN
Sbjct: 204 AVN 206
Score = 30.7 bits (66), Expect = 6.6
Identities = 14/56 (25%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRH 473
C P+P++ W + L + ++V+ +G T+++ + + +D+GTY+C A + +
Sbjct: 155 CPVTGYPKPVVKWTKDSAPLALS--QSVSMEGSTVIVTNANYTDAGTYSCEAVNEY 208
>AF456248-1|AAL59606.1| 265|Caenorhabditis elegans secreted
2-immunoglobulin-domainprotein ZIG-1 protein.
Length = 265
Score = 48.4 bits (110), Expect = 3e-05
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 4/76 (5%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQ 168
EF LE +G++V L C P G P+P V W K+ L M +G +++
Sbjct: 135 EFHLESTGTTVEKGESVTLTC-PVTGYPKPVVKWTKDSAPLALSQSVSM---EGSTVIVT 190
Query: 169 DARQTDAGRYQCIARN 184
+A TDAG Y C A N
Sbjct: 191 NANYTDAGTYSCEAVN 206
Score = 40.3 bits (90), Expect = 0.008
Identities = 24/90 (26%), Positives = 38/90 (42%), Gaps = 5/90 (5%)
Query: 2 SDDYVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL 61
S ++ T E + TV + + TL C G P P ++W K + +S+
Sbjct: 124 SHEHFTEHEGHEFHLESTGTTVEKGESVTLTCPVTGYPKPVVKWTKDSAPLA--LSQSVS 181
Query: 62 PAGGLFFLRATHGRVHSDAGVYWCEATNSY 91
G + + ++DAG Y CEA N Y
Sbjct: 182 MEGSTVIVTNAN---YTDAGTYSCEAVNEY 208
Score = 39.1 bits (87), Expect = 0.019
Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 2/63 (3%)
Query: 214 QTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCE 273
+ G SVT C V G P P V W + + + L + ++ ++ + N D G YSCE
Sbjct: 146 EKGESVTLTCPVTGYPKPVVKWTKDS--APLALSQSVSMEGSTVIVTNANYTDAGTYSCE 203
Query: 274 AEN 276
A N
Sbjct: 204 AVN 206
Score = 36.7 bits (81), Expect = 0.10
Identities = 31/123 (25%), Positives = 48/123 (39%), Gaps = 23/123 (18%)
Query: 266 DEGEYSCEAENSVGAVSASGYL------------TVYDPPSINLSPNSVNVESGNVARFT 313
D GEY CE + G +S ++ T ++ +L VE G T
Sbjct: 95 DAGEYKCELDTPHGKISHKVFIYSRPVVHSHEHFTEHEGHEFHLESTGTTVEKGESVTLT 154
Query: 314 CTATGRPEPTMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCS 373
C TG P+P + W+ + + +S +G TV+ N + D+ T C
Sbjct: 155 CPVTGYPKPVVKWTKDSAPLALSQSVS---------MEGSTVIVTN-ANYTDA-GTYSCE 203
Query: 374 AVN 376
AVN
Sbjct: 204 AVN 206
Score = 30.7 bits (66), Expect = 6.6
Identities = 14/56 (25%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNVTNDG-TLVLKDLDKSDSGTYTCVASSRH 473
C P+P++ W + L + ++V+ +G T+++ + + +D+GTY+C A + +
Sbjct: 155 CPVTGYPKPVVKWTKDSAPLALS--QSVSMEGSTVIVTNANYTDAGTYSCEAVNEY 208
>U67954-4|AAM54180.1| 345|Caenorhabditis elegans
Wrapper/rega-1/klingon homologprotein 1, isoform c
protein.
Length = 345
Score = 48.0 bits (109), Expect = 4e-05
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+V+ C G+P+P V W K L D R H G +VI + ++ AG+Y C+A N
Sbjct: 135 LVITCHVKEGNPKPGVVWTKQAAKLPED-IKREH--GGARIVITEVKKHHAGKYNCLAEN 191
Query: 185 AAGTRESAIATLKIHI 200
AG S AT+ IH+
Sbjct: 192 IAG---SDRATIDIHV 204
Score = 44.4 bits (100), Expect = 5e-04
Identities = 45/204 (22%), Positives = 86/204 (42%), Gaps = 19/204 (9%)
Query: 101 LHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD------ 154
L +A + R + + + +G+++ L C P + W+KN + + D +
Sbjct: 11 LLIASTSAQIRTKGGTLIAKEGESLTLRCEVE--DPSVAIIWRKNTEVVAVDDEILDTYG 68
Query: 155 SRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV 212
++G L I+ ++ Y C A S +K+ +KP ++ P+ V
Sbjct: 69 GYEISMEGSTSVLTIKRVEPINSANYSCAL---AEPEVSVTFVIKVQVKPLVVISPDTGV 125
Query: 213 --AQTGS-SVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
A+ G ++ C V G+P P V+W + A +P + + + V G
Sbjct: 126 YHARVGEKNLVITCHVKEGNPKPGVVWTKQAA--KLPEDIKREHGGARIVITEVKKHHAG 183
Query: 269 EYSCEAENSVGAVSASGYLTVYDP 292
+Y+C AEN G+ A+ + V +P
Sbjct: 184 KYNCLAENIAGSDRATIDIHVAEP 207
>AF456364-1|AAL60235.1| 344|Caenorhabditis elegans immunoglobulin
domain-containingprotein WRK-1C protein.
Length = 344
Score = 48.0 bits (109), Expect = 4e-05
Identities = 28/76 (36%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 125 VVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
+V+ C G+P+P V W K L D R H G +VI + ++ AG+Y C+A N
Sbjct: 134 LVITCHVKEGNPKPGVVWTKQAAKLPED-IKREH--GGARIVITEVKKHHAGKYNCLAEN 190
Query: 185 AAGTRESAIATLKIHI 200
AG S AT+ IH+
Sbjct: 191 IAG---SDRATIDIHV 203
Score = 44.4 bits (100), Expect = 5e-04
Identities = 45/204 (22%), Positives = 86/204 (42%), Gaps = 19/204 (9%)
Query: 101 LHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGD------ 154
L +A + R + + + +G+++ L C P + W+KN + + D +
Sbjct: 10 LLIASTSAQIRTKGGTLIAKEGESLTLRCEVE--DPSVAIIWRKNTEVVAVDDEILDTYG 67
Query: 155 SRMHLVDGGN--LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVV 212
++G L I+ ++ Y C A S +K+ +KP ++ P+ V
Sbjct: 68 GYEISMEGSTSVLTIKRVEPINSANYSCAL---AEPEVSVTFVIKVQVKPLVVISPDTGV 124
Query: 213 --AQTGS-SVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
A+ G ++ C V G+P P V+W + A +P + + + V G
Sbjct: 125 YHARVGEKNLVITCHVKEGNPKPGVVWTKQAA--KLPEDIKREHGGARIVITEVKKHHAG 182
Query: 269 EYSCEAENSVGAVSASGYLTVYDP 292
+Y+C AEN G+ A+ + V +P
Sbjct: 183 KYNCLAENIAGSDRATIDIHVAEP 206
>U29082-1|AAA68401.1| 251|Caenorhabditis elegans 2 (zwei) ig-domain
protein protein3 protein.
Length = 251
Score = 46.4 bits (105), Expect = 1e-04
Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 28/219 (12%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--- 61
++T+ + IIE D TV+ + TL C +P+ I W K G + D ++
Sbjct: 37 HLTTKPSLKIIEGLEDNTVSTGESVTLRCDVLSTPTGVIYWEKDGQRIQGDKELNVFEKV 96
Query: 62 -----PAGGLFFLRATH----GRVHSDAGVYWCEATNSYGTARS------RNATLHVAVL 106
P + +++ +H G Y C ATN + T S T+
Sbjct: 97 LNAMGPTVESGIITSSYQIPCANLHH-IGSYKCVATNGHDTVESSAKISVEGQTVKCKST 155
Query: 107 REE---FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163
R + ES+ Q + L C R N W + + FD R L+ G
Sbjct: 156 RRSAPVITMSTESRFELQDNAATLIC---RADRRANWNWMFEDKKIDFDS-GRYELLPSG 211
Query: 164 NLVIQDARQTDAGRYQCIARNAAGTR--ESAIATLKIHI 200
+L+I+ + +D G Y CIA N G E+ + K HI
Sbjct: 212 DLLIRKIQWSDMGSYFCIAHNKYGESRGETFLYPTKKHI 250
Score = 37.1 bits (82), Expect = 0.076
Identities = 35/143 (24%), Positives = 60/143 (41%), Gaps = 8/143 (5%)
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
A +G + N +S T K +K +I G ED TG SVT +C V P
Sbjct: 14 AHPLSSGEMRAAVSNLVREIDSTHLTTKPSLK--IIEGLEDNTVSTGESVTLRCDVLSTP 71
Query: 230 LPDVLWRRSAG--GGNMPLGRV-KVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSA 283
+ W + G+ L KVL+ +++ I+ + C + +G+ V+
Sbjct: 72 TGVIYWEKDGQRIQGDKELNVFEKVLNAMGPTVESGIITSSYQIPCANLHHIGSYKCVAT 131
Query: 284 SGYLTVYDPPSINLSPNSVNVES 306
+G+ TV I++ +V +S
Sbjct: 132 NGHDTVESSAKISVEGQTVKCKS 154
Score = 33.1 bits (72), Expect = 1.2
Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 3/94 (3%)
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQN 441
V G+ R P+IT ++ + A C A W FE + + +
Sbjct: 145 VEGQTVKCKSTRRSAPVITMSTESRFELQDNAATLICRA--DRRANWNWMFEDKKIDFDS 202
Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
R + G L+++ + SD G+Y C+A +++G+
Sbjct: 203 GRYELLPSGDLLIRKIQWSDMGSYFCIAHNKYGE 236
>AF456250-1|AAL59608.1| 251|Caenorhabditis elegans secreted
2-immunoglobulin-domainprotein ZIG-3 protein.
Length = 251
Score = 46.4 bits (105), Expect = 1e-04
Identities = 55/219 (25%), Positives = 86/219 (39%), Gaps = 28/219 (12%)
Query: 5 YVTSGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSIL--- 61
++T+ + IIE D TV+ + TL C +P+ I W K G + D ++
Sbjct: 37 HLTTKPSLKIIEGLEDNTVSTGESVTLRCDVLSTPTGVIYWEKDGQRIQGDKELNVFEKV 96
Query: 62 -----PAGGLFFLRATH----GRVHSDAGVYWCEATNSYGTARS------RNATLHVAVL 106
P + +++ +H G Y C ATN + T S T+
Sbjct: 97 LNAMGPTVESGIITSSYQIPCANLHH-IGSYKCVATNGHDTVESSAKISVEGQTVKCKST 155
Query: 107 REE---FRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG 163
R + ES+ Q + L C R N W + + FD R L+ G
Sbjct: 156 RRSAPVITMSTESRFELQDNAATLIC---RADRRANWNWMFEDKKIDFDS-GRYELLPSG 211
Query: 164 NLVIQDARQTDAGRYQCIARNAAGTR--ESAIATLKIHI 200
+L+I+ + +D G Y CIA N G E+ + K HI
Sbjct: 212 DLLIRKIQWSDMGSYFCIAHNKYGESRGETFLYPTKKHI 250
Score = 37.1 bits (82), Expect = 0.076
Identities = 35/143 (24%), Positives = 60/143 (41%), Gaps = 8/143 (5%)
Query: 170 ARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDP 229
A +G + N +S T K +K +I G ED TG SVT +C V P
Sbjct: 14 AHPLSSGEMRAAVSNLVREIDSTHLTTKPSLK--IIEGLEDNTVSTGESVTLRCDVLSTP 71
Query: 230 LPDVLWRRSAG--GGNMPLGRV-KVLDDGSLRLDNVILADEGEYSCEAENSVGA---VSA 283
+ W + G+ L KVL+ +++ I+ + C + +G+ V+
Sbjct: 72 TGVIYWEKDGQRIQGDKELNVFEKVLNAMGPTVESGIITSSYQIPCANLHHIGSYKCVAT 131
Query: 284 SGYLTVYDPPSINLSPNSVNVES 306
+G+ TV I++ +V +S
Sbjct: 132 NGHDTVESSAKISVEGQTVKCKS 154
Score = 33.1 bits (72), Expect = 1.2
Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 3/94 (3%)
Query: 383 VRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEAL-IQN 441
V G+ R P+IT ++ + A C A W FE + + +
Sbjct: 145 VEGQTVKCKSTRRSAPVITMSTESRFELQDNAATLICRA--DRRANWNWMFEDKKIDFDS 202
Query: 442 HRRNVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
R + G L+++ + SD G+Y C+A +++G+
Sbjct: 203 GRYELLPSGDLLIRKIQWSDMGSYFCIAHNKYGE 236
>Z81086-3|CAD56586.1| 711|Caenorhabditis elegans Hypothetical
protein F53B6.2b protein.
Length = 711
Score = 46.0 bits (104), Expect = 2e-04
Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG ++ ++C P + + +YWKKNG+ + D+ + + GNL + AR DAG Y+C
Sbjct: 332 QGTSIKIKC-PAKKFDKKKIYWKKNGKKI--KNDAHIKVSANGNLRVFHARMEDAGVYEC 388
Query: 181 IARNAAG 187
G
Sbjct: 389 FTDRLQG 395
Score = 31.1 bits (67), Expect = 5.0
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
+ C A I W K G + +D H + G LR H R+ DAGVY C
Sbjct: 338 IKCPAKKFDKKKIYWKKNGKKIKNDAHIKVSANGN---LRVFHARM-EDAGVYEC 388
>Z81086-2|CAB03121.3| 1045|Caenorhabditis elegans Hypothetical
protein F53B6.2a protein.
Length = 1045
Score = 46.0 bits (104), Expect = 2e-04
Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Query: 121 QGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQC 180
QG ++ ++C P + + +YWKKNG+ + D+ + + GNL + AR DAG Y+C
Sbjct: 666 QGTSIKIKC-PAKKFDKKKIYWKKNGKKI--KNDAHIKVSANGNLRVFHARMEDAGVYEC 722
Query: 181 IARNAAG 187
G
Sbjct: 723 FTDRLQG 729
Score = 31.1 bits (67), Expect = 5.0
Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 4/55 (7%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWC 85
+ C A I W K G + +D H + G LR H R+ DAGVY C
Sbjct: 672 IKCPAKKFDKKKIYWKKNGKKIKNDAHIKVSANGN---LRVFHARM-EDAGVYEC 722
>Z68116-7|CAA92170.1| 238|Caenorhabditis elegans Hypothetical
protein F42F12.2 protein.
Length = 238
Score = 46.0 bits (104), Expect = 2e-04
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 18/192 (9%)
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR------TIIFPGMSRD-KYHATAVF 350
+PN NV G +C A G P P+++W + G R + ++ + D K + A
Sbjct: 38 TPNDSNVTFGEKFVLSCGANGAPLPSIYWELNGMRIQGEETSNVYENILNDGKQVSNAAM 97
Query: 351 DGVTVLTINDTDKNDSRNTIVC----SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406
T +N + + + + FV G T + +D P I+
Sbjct: 98 VSSHYRIPCATARNSGAYKCIIDNGLTKLEHVAKVFVGGNKTNCALNDNGAPFISMTVDF 157
Query: 407 QTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQN--HRRNVTNDGTLVLKDLDKSDSG 463
+ L I + AV C E W + +GE L+ N R + G L+++++ SD G
Sbjct: 158 R-LEISNNAV---ALSCRSETATEWSWHKGEQLLTNDGERYQMFPSGDLIIRNISWSDMG 213
Query: 464 TYTCVASSRHGK 475
Y C A + G+
Sbjct: 214 EYNCTARNHFGE 225
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/191 (25%), Positives = 73/191 (38%), Gaps = 26/191 (13%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV----VSDTHRSILPAGGLFFLRA-- 71
P D V + L+C A G+P P+I W G+ + S+ + +IL G A
Sbjct: 39 PNDSNVTFGEKFVLSCGANGAPLPSIYWELNGMRIQGEETSNVYENILNDGKQVSNAAMV 98
Query: 72 -THGRVHS----DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES---------- 116
+H R+ ++G Y C N T A + V + L
Sbjct: 99 SSHYRIPCATARNSGAYKCIIDNGL-TKLEHVAKVFVGGNKTNCALNDNGAPFISMTVDF 157
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176
+ + V L C R W K Q L DG+ R + G+L+I++ +D G
Sbjct: 158 RLEISNNAVALSC---RSETATEWSWHKGEQLLTNDGE-RYQMFPSGDLIIRNISWSDMG 213
Query: 177 RYQCIARNAAG 187
Y C ARN G
Sbjct: 214 EYNCTARNHFG 224
Score = 42.7 bits (96), Expect = 0.002
Identities = 44/202 (21%), Positives = 79/202 (39%), Gaps = 26/202 (12%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH--LVDGGNLV 166
+F P G+ VL C G+P P++YW+ NG + + S ++ +++ G V
Sbjct: 34 KFTRTPNDSNVTFGEKFVLSC-GANGAPLPSIYWELNGMRIQGEETSNVYENILNDGKQV 92
Query: 167 -----------IQDARQTDAGRYQCIARNAAGTRESAI----------ATLKIHIKPYLI 205
I A ++G Y+CI N E L + P++
Sbjct: 93 SNAAMVSSHYRIPCATARNSGAYKCIIDNGLTKLEHVAKVFVGGNKTNCALNDNGAPFIS 152
Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
+ + + ++V CR + + W + R ++ G L + N+ +
Sbjct: 153 MTVDFRLEISNNAVALSCR--SETATEWSWHKGEQLLTNDGERYQMFPSGDLIIRNISWS 210
Query: 266 DEGEYSCEAENSVGAVSASGYL 287
D GEY+C A N G +A +L
Sbjct: 211 DMGEYNCTARNHFGETTAITFL 232
>U00054-3|AAM48546.1| 12268|Caenorhabditis elegans Hypothetical
protein K07E12.1b protein.
Length = 12268
Score = 46.0 bits (104), Expect = 2e-04
Identities = 85/424 (20%), Positives = 158/424 (37%), Gaps = 46/424 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
++C + P P I W+K + ++ L A + ++ + + C + N
Sbjct: 262 ISCTSVAYPFPDIYWFKNQKVNTDGPDQNTLRASQILIIKEIYRNEE-----FTCVSDNI 316
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDT-VVLECLPPRGSPEP----NVYWKKN 145
+G+A N T+ + V P K ++ G T + + PP P +Y+ N
Sbjct: 317 HGSA---NRTVSIVVTGPGSA--PHLKSASAGRTSLTVRWEPPSIINRPITTYTLYYTNN 371
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT----RESAIATLKIHIK 201
Q + + + I D R A + A + G + I TLK ++
Sbjct: 372 PQQPVKNWKKLEVKEPTREVAIPDLRPDTAYYIRVRANDPLGPGKLGNQVQIKTLKPAVR 431
Query: 202 PYL-ITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
PY+ I +++ ++ C V DP+P ++W PL + +++
Sbjct: 432 PYVNIVEGDEIRVPPMTAFEIDCNVTRADPVPVLVWLHKG----RPLNKGSKTQH--IKM 485
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
N + + ++SC AEN G + +TV P + ++ + + T
Sbjct: 486 KNGGVLESTQFSCVAENEAGKSTKKINVTVTGPSAPERIRYQIDGDKVTLQWEPPQITNG 545
Query: 320 PEP--TMFWSVEGNRTIIFPGMSRDKYHATAVFD----GVTVLTINDTDKNDSRNTIVCS 373
P +F++ + P + RD++ + D TVL +N+ + T V
Sbjct: 546 PMAGYDVFYTED-------PSLPRDQWKVHHIDDPNARTTTVLRLNE----KTPYTFVIV 594
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL--PIKSMAVFPCTAICTPEPIIAW 431
N G T T+ PP++ PS + P + C A P+P I W
Sbjct: 595 GRNRLGPGLPSAPFTATTWLAAKPPVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIW 654
Query: 432 YFEG 435
+ G
Sbjct: 655 LWSG 658
Score = 40.3 bits (90), Expect = 0.008
Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 12/93 (12%)
Query: 397 PPIITNGPSNQTLPIKSM--AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
PP IT PSN T ++ + A CTA P+P + W I+ + V + TL L
Sbjct: 1139 PPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHW-------IKANGETV-DSATLQL 1190
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
DL K S TCVA + GK + ++ V P
Sbjct: 1191 YDLVKDTSA--TCVAENNAGKTQEAVSIQVTGP 1221
Score = 38.3 bits (85), Expect = 0.033
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 292 PPSINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
PP+I L P++ VE A TCTATG P+P + W T+
Sbjct: 1139 PPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHWIKANGETV 1183
Score = 35.1 bits (77), Expect = 0.31
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDN 261
+ G + GS +T C G PLP V W ++ GN + +V DG+ L
Sbjct: 1758 VEGSTTIQILPGSQMTIACNATGIPLPQVKWIKA---GNYEIDPSRVDADGNHAQFSLQV 1814
Query: 262 VILADEGEYSCEAENSVG 279
+ ++ ++C A+N +G
Sbjct: 1815 ANITEDTTFNCVAQNPLG 1832
Score = 31.1 bits (67), Expect = 5.0
Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 8/149 (5%)
Query: 684 LHSNDVSGFEITSLRKY--TKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMF 741
+HS+D S++ Y T + L+ + +G + V + + P P N E+
Sbjct: 881 IHSDDSQPHHYNSIQVYSTTATKRILLCQARNPDGTVDDRHVF--IVNKPGSAPQNPEVI 938
Query: 742 ILNTTTVHLKWSPPELQLQNGIITGYNVVVNW-LDVPANKSMV-AINTTVHQATSLIMTN 799
+ V + W PP + NG IT YNV + +P ++ V ++ L
Sbjct: 939 VDPDNRVTITWQPP--KYPNGEITSYNVYITGDPSLPVDQWQVFPVDDVTDPKLVLQRGA 996
Query: 800 LTSGVSYSVQIAAETIIGLGPFSQKVYFN 828
L Y V+IAA G G + +F+
Sbjct: 997 LQPETPYFVKIAAVNPHGEGIHTDPKHFD 1025
>U00054-2|AAA50715.2| 13100|Caenorhabditis elegans Hypothetical
protein K07E12.1a protein.
Length = 13100
Score = 46.0 bits (104), Expect = 2e-04
Identities = 85/424 (20%), Positives = 158/424 (37%), Gaps = 46/424 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
++C + P P I W+K + ++ L A + ++ + + C + N
Sbjct: 325 ISCTSVAYPFPDIYWFKNQKVNTDGPDQNTLRASQILIIKEIYRNEE-----FTCVSDNI 379
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDT-VVLECLPPRGSPEP----NVYWKKN 145
+G+A N T+ + V P K ++ G T + + PP P +Y+ N
Sbjct: 380 HGSA---NRTVSIVVTGPGSA--PHLKSASAGRTSLTVRWEPPSIINRPITTYTLYYTNN 434
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT----RESAIATLKIHIK 201
Q + + + I D R A + A + G + I TLK ++
Sbjct: 435 PQQPVKNWKKLEVKEPTREVAIPDLRPDTAYYIRVRANDPLGPGKLGNQVQIKTLKPAVR 494
Query: 202 PYL-ITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
PY+ I +++ ++ C V DP+P ++W PL + +++
Sbjct: 495 PYVNIVEGDEIRVPPMTAFEIDCNVTRADPVPVLVWLHKG----RPLNKGSKTQH--IKM 548
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
N + + ++SC AEN G + +TV P + ++ + + T
Sbjct: 549 KNGGVLESTQFSCVAENEAGKSTKKINVTVTGPSAPERIRYQIDGDKVTLQWEPPQITNG 608
Query: 320 PEP--TMFWSVEGNRTIIFPGMSRDKYHATAVFD----GVTVLTINDTDKNDSRNTIVCS 373
P +F++ + P + RD++ + D TVL +N+ + T V
Sbjct: 609 PMAGYDVFYTED-------PSLPRDQWKVHHIDDPNARTTTVLRLNE----KTPYTFVIV 657
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL--PIKSMAVFPCTAICTPEPIIAW 431
N G T T+ PP++ PS + P + C A P+P I W
Sbjct: 658 GRNRLGPGLPSAPFTATTWLAAKPPVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIW 717
Query: 432 YFEG 435
+ G
Sbjct: 718 LWSG 721
Score = 40.3 bits (90), Expect = 0.008
Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 12/93 (12%)
Query: 397 PPIITNGPSNQTLPIKSM--AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
PP IT PSN T ++ + A CTA P+P + W I+ + V + TL L
Sbjct: 1202 PPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHW-------IKANGETV-DSATLQL 1253
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
DL K S TCVA + GK + ++ V P
Sbjct: 1254 YDLVKDTSA--TCVAENNAGKTQEAVSIQVTGP 1284
Score = 38.3 bits (85), Expect = 0.033
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 292 PPSINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
PP+I L P++ VE A TCTATG P+P + W T+
Sbjct: 1202 PPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHWIKANGETV 1246
Score = 35.1 bits (77), Expect = 0.31
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDN 261
+ G + GS +T C G PLP V W ++ GN + +V DG+ L
Sbjct: 1821 VEGSTTIQILPGSQMTIACNATGIPLPQVKWIKA---GNYEIDPSRVDADGNHAQFSLQV 1877
Query: 262 VILADEGEYSCEAENSVG 279
+ ++ ++C A+N +G
Sbjct: 1878 ANITEDTTFNCVAQNPLG 1895
Score = 31.1 bits (67), Expect = 5.0
Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 8/149 (5%)
Query: 684 LHSNDVSGFEITSLRKY--TKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMF 741
+HS+D S++ Y T + L+ + +G + V + + P P N E+
Sbjct: 944 IHSDDSQPHHYNSIQVYSTTATKRILLCQARNPDGTVDDRHVF--IVNKPGSAPQNPEVI 1001
Query: 742 ILNTTTVHLKWSPPELQLQNGIITGYNVVVNW-LDVPANKSMV-AINTTVHQATSLIMTN 799
+ V + W PP + NG IT YNV + +P ++ V ++ L
Sbjct: 1002 VDPDNRVTITWQPP--KYPNGEITSYNVYITGDPSLPVDQWQVFPVDDVTDPKLVLQRGA 1059
Query: 800 LTSGVSYSVQIAAETIIGLGPFSQKVYFN 828
L Y V+IAA G G + +F+
Sbjct: 1060 LQPETPYFVKIAAVNPHGEGIHTDPKHFD 1088
>AY117398-1|AAM78593.1| 13100|Caenorhabditis elegans mesocentin
protein.
Length = 13100
Score = 46.0 bits (104), Expect = 2e-04
Identities = 85/424 (20%), Positives = 158/424 (37%), Gaps = 46/424 (10%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDAGVYWCEATNS 90
++C + P P I W+K + ++ L A + ++ + + C + N
Sbjct: 325 ISCTSVAYPFPDIYWFKNQKVNTDGPDQNTLRASQILIIKEIYRNEE-----FTCVSDNI 379
Query: 91 YGTARSRNATLHVAVLREEFRLEPESKQSAQGDT-VVLECLPPRGSPEP----NVYWKKN 145
+G+A N T+ + V P K ++ G T + + PP P +Y+ N
Sbjct: 380 HGSA---NRTVSIVVTGPGSA--PHLKSASAGRTSLTVRWEPPSIINRPITTYTLYYTNN 434
Query: 146 GQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGT----RESAIATLKIHIK 201
Q + + + I D R A + A + G + I TLK ++
Sbjct: 435 PQQPVKNWKKLEVKEPTREVAIPDLRPDTAYYIRVRANDPLGPGKLGNQVQIKTLKPAVR 494
Query: 202 PYL-ITGPEDVVAQTGSSVTFQCRVG-GDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRL 259
PY+ I +++ ++ C V DP+P ++W PL + +++
Sbjct: 495 PYVNIVEGDEIRVPPMTAFEIDCNVTRADPVPVLVWLHKG----RPLNKGSKTQH--IKM 548
Query: 260 DNVILADEGEYSCEAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGR 319
N + + ++SC AEN G + +TV P + ++ + + T
Sbjct: 549 KNGGVLESTQFSCVAENEAGKSTKKINVTVTGPSAPERIRYQIDGDKVTLQWEPPQITNG 608
Query: 320 PEP--TMFWSVEGNRTIIFPGMSRDKYHATAVFD----GVTVLTINDTDKNDSRNTIVCS 373
P +F++ + P + RD++ + D TVL +N+ + T V
Sbjct: 609 PMAGYDVFYTED-------PSLPRDQWKVHHIDDPNARTTTVLRLNE----KTPYTFVIV 657
Query: 374 AVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTL--PIKSMAVFPCTAICTPEPIIAW 431
N G T T+ PP++ PS + P + C A P+P I W
Sbjct: 658 GRNRLGPGLPSAPFTATTWLAAKPPVVQLEPSEEMTKEPSNDEMIIECGAQGVPKPKIIW 717
Query: 432 YFEG 435
+ G
Sbjct: 718 LWSG 721
Score = 40.3 bits (90), Expect = 0.008
Identities = 32/93 (34%), Positives = 44/93 (47%), Gaps = 12/93 (12%)
Query: 397 PPIITNGPSNQTLPIKSM--AVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVL 454
PP IT PSN T ++ + A CTA P+P + W I+ + V + TL L
Sbjct: 1202 PPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHW-------IKANGETV-DSATLQL 1253
Query: 455 KDLDKSDSGTYTCVASSRHGKYVWSGALLVDSP 487
DL K S TCVA + GK + ++ V P
Sbjct: 1254 YDLVKDTSA--TCVAENNAGKTQEAVSIQVTGP 1284
Score = 38.3 bits (85), Expect = 0.033
Identities = 18/45 (40%), Positives = 24/45 (53%), Gaps = 2/45 (4%)
Query: 292 PPSINLSPNS--VNVESGNVARFTCTATGRPEPTMFWSVEGNRTI 334
PP+I L P++ VE A TCTATG P+P + W T+
Sbjct: 1202 PPTITLDPSNSTYTVEPLGAATITCTATGVPQPKVHWIKANGETV 1246
Score = 35.1 bits (77), Expect = 0.31
Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 6/78 (7%)
Query: 205 ITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS---LRLDN 261
+ G + GS +T C G PLP V W ++ GN + +V DG+ L
Sbjct: 1821 VEGSTTIQILPGSQMTIACNATGIPLPQVKWIKA---GNYEIDPSRVDADGNHAQFSLQV 1877
Query: 262 VILADEGEYSCEAENSVG 279
+ ++ ++C A+N +G
Sbjct: 1878 ANITEDTTFNCVAQNPLG 1895
Score = 31.1 bits (67), Expect = 5.0
Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 8/149 (5%)
Query: 684 LHSNDVSGFEITSLRKY--TKYEFFLIPFYKKFEGKPSNSRVAQTLDDVPDGPPINIEMF 741
+HS+D S++ Y T + L+ + +G + V + + P P N E+
Sbjct: 944 IHSDDSQPHHYNSIQVYSTTATKRILLCQARNPDGTVDDRHVF--IVNKPGSAPQNPEVI 1001
Query: 742 ILNTTTVHLKWSPPELQLQNGIITGYNVVVNW-LDVPANKSMV-AINTTVHQATSLIMTN 799
+ V + W PP + NG IT YNV + +P ++ V ++ L
Sbjct: 1002 VDPDNRVTITWQPP--KYPNGEITSYNVYITGDPSLPVDQWQVFPVDDVTDPKLVLQRGA 1059
Query: 800 LTSGVSYSVQIAAETIIGLGPFSQKVYFN 828
L Y V+IAA G G + +F+
Sbjct: 1060 LQPETPYFVKIAAVNPHGEGIHTDPKHFD 1088
>AF456249-1|AAL59607.1| 238|Caenorhabditis elegans secreted
2-immunoglobulin-domainprotein ZIG-2 protein.
Length = 238
Score = 46.0 bits (104), Expect = 2e-04
Identities = 46/192 (23%), Positives = 78/192 (40%), Gaps = 18/192 (9%)
Query: 298 SPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNR------TIIFPGMSRD-KYHATAVF 350
+PN NV G +C A G P P+++W + G R + ++ + D K + A
Sbjct: 38 TPNDSNVTFGEKFVLSCGANGAPLPSIYWELNGMRIQGEETSNVYENILNDGKQVSNAAM 97
Query: 351 DGVTVLTINDTDKNDSRNTIVC----SAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSN 406
T +N + + + + FV G T + +D P I+
Sbjct: 98 VSSHYRIPCATARNSGAYKCIIDNGLTKLEHVAKVFVGGNKTNCALNDNGAPFISMTVDF 157
Query: 407 QTLPIKSMAVFPCTAICTPEPIIAW-YFEGEALIQN--HRRNVTNDGTLVLKDLDKSDSG 463
+ L I + AV C E W + +GE L+ N R + G L+++++ SD G
Sbjct: 158 R-LEISNNAV---ALSCRSETATEWSWHKGEQLLTNDGERYQMFPSGDLIIRNISWSDMG 213
Query: 464 TYTCVASSRHGK 475
Y C A + G+
Sbjct: 214 EYNCTARNHFGE 225
Score = 43.2 bits (97), Expect = 0.001
Identities = 49/191 (25%), Positives = 73/191 (38%), Gaps = 26/191 (13%)
Query: 18 PLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLV----VSDTHRSILPAGGLFFLRA-- 71
P D V + L+C A G+P P+I W G+ + S+ + +IL G A
Sbjct: 39 PNDSNVTFGEKFVLSCGANGAPLPSIYWELNGMRIQGEETSNVYENILNDGKQVSNAAMV 98
Query: 72 -THGRVHS----DAGVYWCEATNSYGTARSRNATLHVAVLREEFRLEPES---------- 116
+H R+ ++G Y C N T A + V + L
Sbjct: 99 SSHYRIPCATARNSGAYKCIIDNGL-TKLEHVAKVFVGGNKTNCALNDNGAPFISMTVDF 157
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAG 176
+ + V L C R W K Q L DG+ R + G+L+I++ +D G
Sbjct: 158 RLEISNNAVALSC---RSETATEWSWHKGEQLLTNDGE-RYQMFPSGDLIIRNISWSDMG 213
Query: 177 RYQCIARNAAG 187
Y C ARN G
Sbjct: 214 EYNCTARNHFG 224
Score = 42.7 bits (96), Expect = 0.002
Identities = 44/202 (21%), Positives = 79/202 (39%), Gaps = 26/202 (12%)
Query: 109 EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH--LVDGGNLV 166
+F P G+ VL C G+P P++YW+ NG + + S ++ +++ G V
Sbjct: 34 KFTRTPNDSNVTFGEKFVLSC-GANGAPLPSIYWELNGMRIQGEETSNVYENILNDGKQV 92
Query: 167 -----------IQDARQTDAGRYQCIARNAAGTRESAI----------ATLKIHIKPYLI 205
I A ++G Y+CI N E L + P++
Sbjct: 93 SNAAMVSSHYRIPCATARNSGAYKCIIDNGLTKLEHVAKVFVGGNKTNCALNDNGAPFIS 152
Query: 206 TGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILA 265
+ + + ++V CR + + W + R ++ G L + N+ +
Sbjct: 153 MTVDFRLEISNNAVALSCR--SETATEWSWHKGEQLLTNDGERYQMFPSGDLIIRNISWS 210
Query: 266 DEGEYSCEAENSVGAVSASGYL 287
D GEY+C A N G +A +L
Sbjct: 211 DMGEYNCTARNHFGETTAITFL 232
>Z69664-7|CAA93513.2| 1159|Caenorhabditis elegans Hypothetical
protein K04D7.4 protein.
Length = 1159
Score = 45.6 bits (103), Expect = 2e-04
Identities = 35/109 (32%), Positives = 48/109 (44%), Gaps = 10/109 (9%)
Query: 504 PGPPTKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVI 563
P P+ P T+ S+TL W+ N IL + V V T+S N V+
Sbjct: 140 PVAPSSPEIKTFTNRSITLVWTHNAARAHRPILRFSVSV---RTVSDNTR-------FVM 189
Query: 564 ARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSN 612
A + T +V +L P Y F VR ENS G S P + T+G+ N
Sbjct: 190 AAPSNATTVIVDNLSPYTLYAFSVRAENSAGSSDFGPETTFRTLGESPN 238
>U23452-9|AAU87820.1| 155|Caenorhabditis elegans Hypothetical
protein R07G3.9 protein.
Length = 155
Score = 45.6 bits (103), Expect = 2e-04
Identities = 32/95 (33%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
Query: 388 TVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEG-----EALIQNH 442
TV SD+ R IIT +QT + + C A P P I WY EG +A I +
Sbjct: 50 TVLSDN-RSAQIITGSHFSQTYRLGYKLLIICKARGDPRPTIKWYKEGAEIQPKASIHYY 108
Query: 443 RRNVTNDGTLVLKDLDKS---DSGTYTCVASSRHG 474
+ + ND ++D + D G Y CVA++ HG
Sbjct: 109 EKPIENDTIWSKLEVDPATMGDQGVYACVANNPHG 143
Score = 33.5 bits (73), Expect = 0.93
Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 4/64 (6%)
Query: 33 CRAGGSPSPAIRWYKGGVLV--VSDTHRSILPAGG--LFFLRATHGRVHSDAGVYWCEAT 88
C+A G P P I+WYK G + + H P ++ D GVY C A
Sbjct: 80 CKARGDPRPTIKWYKEGAEIQPKASIHYYEKPIENDTIWSKLEVDPATMGDQGVYACVAN 139
Query: 89 NSYG 92
N +G
Sbjct: 140 NPHG 143
Score = 31.5 bits (68), Expect = 3.8
Identities = 22/88 (25%), Positives = 39/88 (44%), Gaps = 10/88 (11%)
Query: 204 LITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV----KVLDDGS-- 256
+ITG + G + C+ GDP P + W + G P + K +++ +
Sbjct: 60 IITGSHFSQTYRLGYKLLIICKARGDPRPTIKWYKE-GAEIQPKASIHYYEKPIENDTIW 118
Query: 257 --LRLDNVILADEGEYSCEAENSVGAVS 282
L +D + D+G Y+C A N G ++
Sbjct: 119 SKLEVDPATMGDQGVYACVANNPHGVMA 146
>AC087079-12|AAK27874.2| 472|Caenorhabditis elegans Hypothetical
protein Y37E3.13 protein.
Length = 472
Score = 44.0 bits (99), Expect = 7e-04
Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 5/79 (6%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQN-HRRNVTNDG----T 451
P ++T+ P + + + V CTA+ TP P + W F G+ + +++++ G
Sbjct: 225 PTVVTSSPESAVVSLDDAHVMCCTALATPSPQLYWQFNGKNISSGLSQKHLSESGKLEFC 284
Query: 452 LVLKDLDKSDSGTYTCVAS 470
L + + D G Y CVAS
Sbjct: 285 LEIPKVRLKDMGKYKCVAS 303
Score = 43.2 bits (97), Expect = 0.001
Identities = 28/82 (34%), Positives = 41/82 (50%), Gaps = 7/82 (8%)
Query: 114 PESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN----LVIQD 169
PES + D V+ C +P P +YW+ NG+ + G S+ HL + G L I
Sbjct: 232 PESAVVSLDDAHVM-CCTALATPSPQLYWQFNGKN-ISSGLSQKHLSESGKLEFCLEIPK 289
Query: 170 ARQTDAGRYQCIARNAAGTRES 191
R D G+Y+C+A + AG S
Sbjct: 290 VRLKDMGKYKCVA-SLAGLNSS 310
Score = 32.7 bits (71), Expect = 1.6
Identities = 17/56 (30%), Positives = 24/56 (42%), Gaps = 2/56 (3%)
Query: 286 YLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMFWSVEGNRTIIFPGMSR 341
+ TV P + SP S V + CTA P P ++W G I G+S+
Sbjct: 219 FQTVCGPTVVTSSPESAVVSLDDAHVMCCTALATPSPQLYWQFNGKN--ISSGLSQ 272
>Z93395-1|CAB07704.1| 1160|Caenorhabditis elegans Hypothetical
protein ZC101.2b protein.
Length = 1160
Score = 41.5 bits (93), Expect = 0.004
Identities = 34/135 (25%), Positives = 53/135 (39%), Gaps = 12/135 (8%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTND---GTLV 453
P ++ +N +P + C A+ PEP I W + + R T++ GTL
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGTLT 330
Query: 454 LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFFRAADVSSLPGPPTKPITH 513
+ D D G YTC A + G+ + + +V +P P PPT P
Sbjct: 331 IHDAQPVDQGAYTCEAINVKGRVLATPDCIVRVVDDPR---------PQPPQPPTAPPQR 381
Query: 514 NVTDTSVTLSWSQNN 528
DT ++ NN
Sbjct: 382 ASCDTRGAVTPYPNN 396
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/134 (29%), Positives = 49/134 (36%), Gaps = 18/134 (13%)
Query: 267 EGEYSC-EAENSVGAVSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEPTMF 325
+G C + + VG V TV DPP NL V G TC A PEP +
Sbjct: 254 DGTNDCHDGSDEVGCVQP----TVVDPPQTNLQ-----VPRGTTFSLTCKAVAVPEPYIN 304
Query: 326 WSVEGNRTIIFPGMSRDKYHATAVFDGVTVLTINDTDKNDSRNTIVCSAVNYAGSSFVRG 385
W + P + T+ G LTI+D D + C A+N G
Sbjct: 305 WRLNWG-----PVCEPPRCLQTSE-GGYGTLTIHDAQPVD-QGAYTCEAINVKGRVLATP 357
Query: 386 KLTV-TSDDDRPPP 398
V DD RP P
Sbjct: 358 DCIVRVVDDPRPQP 371
Score = 35.5 bits (78), Expect = 0.23
Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 9/94 (9%)
Query: 208 PEDVVAQTGSSVTFQCRV---GGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVIL 264
P + + G V+F+CR P V W R G PL G L ++ V L
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGG----PLPSSAHDSGGRLTINPVQL 106
Query: 265 ADEGEYSCEAENSVGAVSASGYLTV--YDPPSIN 296
+D G Y C ++ + V A L+V Y P ++
Sbjct: 107 SDAGTYICVSDYNGNTVEARATLSVVSYGPQEVS 140
Score = 35.1 bits (77), Expect = 0.31
Identities = 22/88 (25%), Positives = 44/88 (50%), Gaps = 3/88 (3%)
Query: 200 IKPYLITGPE-DVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDG--S 256
++P ++ P+ ++ G++ + C+ P P + WR + G P ++ + G +
Sbjct: 269 VQPTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRCLQTSEGGYGT 328
Query: 257 LRLDNVILADEGEYSCEAENSVGAVSAS 284
L + + D+G Y+CEA N G V A+
Sbjct: 329 LTIHDAQPVDQGAYTCEAINVKGRVLAT 356
Score = 33.5 bits (73), Expect = 0.93
Identities = 23/82 (28%), Positives = 35/82 (42%), Gaps = 2/82 (2%)
Query: 12 PYIIEQP-LDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
P +++ P ++ V R +L C+A P P I W + V + R + + G +
Sbjct: 271 PTVVDPPQTNLQVPRGTTFSLTCKAVAVPEPYINW-RLNWGPVCEPPRCLQTSEGGYGTL 329
Query: 71 ATHGRVHSDAGVYWCEATNSYG 92
H D G Y CEA N G
Sbjct: 330 TIHDAQPVDQGAYTCEAINVKG 351
Score = 33.1 bits (72), Expect = 1.2
Identities = 29/87 (33%), Positives = 36/87 (41%), Gaps = 8/87 (9%)
Query: 114 PESKQSAQGDTVVLECLPPRG--SPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR 171
P K+ G V EC S P V W + G L S H GG L I +
Sbjct: 51 PSEKEVRDGRDVSFECRARTSDNSVYPTVRWARVGGPL----PSSAH-DSGGRLTINPVQ 105
Query: 172 QTDAGRYQCIARNAAGTRESAIATLKI 198
+DAG Y C++ T E A ATL +
Sbjct: 106 LSDAGTYICVSDYNGNTVE-ARATLSV 131
Score = 32.3 bits (70), Expect = 2.2
Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 4/72 (5%)
Query: 118 QSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGG--NLVIQDARQTDA 175
Q +G T L C PEP + W+ N + + + +GG L I DA+ D
Sbjct: 282 QVPRGTTFSLTCKAV-AVPEPYINWRLNWGPVC-EPPRCLQTSEGGYGTLTIHDAQPVDQ 339
Query: 176 GRYQCIARNAAG 187
G Y C A N G
Sbjct: 340 GAYTCEAINVKG 351
>Z81045-4|CAB54202.2| 402|Caenorhabditis elegans Hypothetical
protein C36F7.4b protein.
Length = 402
Score = 40.7 bits (91), Expect = 0.006
Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 257 LRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
L L V EY C A N + S + L V PP + +V G++AR CT
Sbjct: 197 LHLTKVSRKHMSEYLCVASNGIPPDESWTVKLLVTFPPLVQAQSETVQASVGSMARMVCT 256
Query: 316 ATGRPEPTMFWSVEG 330
P P M W +G
Sbjct: 257 TEAWPRPEMGWEKDG 271
Score = 35.9 bits (79), Expect = 0.18
Identities = 30/122 (24%), Positives = 52/122 (42%), Gaps = 8/122 (6%)
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
Y C A+N S L V + + E+ Q++ G + C P P + W
Sbjct: 210 YLCVASNGIPPDESWTVKLLVT-FPPLVQAQSETVQASVGSMARMVCTT-EAWPRPEMGW 267
Query: 143 KKNGQTLLFDGDSRM-HLVDGGN-----LVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
+K+G+ + + M H V G L I++ + + G Y+C+A+N G S +
Sbjct: 268 EKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRCVAKNDNGIHHSQVTLN 327
Query: 197 KI 198
+I
Sbjct: 328 QI 329
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 8/86 (9%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT----- 451
PP++ + SMA CT P P + W +GE + +++ +T+ +
Sbjct: 233 PPLVQAQSETVQASVGSMARMVCTTEAWPRPEMGWEKDGEPVYESNNVAMTHTVSGQYHS 292
Query: 452 ---LVLKDLDKSDSGTYTCVASSRHG 474
L ++++ S G Y CVA + +G
Sbjct: 293 VHILEIRNVQSSHFGVYRCVAKNDNG 318
Score = 32.7 bits (71), Expect = 1.6
Identities = 20/84 (23%), Positives = 30/84 (35%)
Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
D + + G L + + Y C+A N ES L + P + E V A
Sbjct: 186 DVKASVFHGPVLHLTKVSRKHMSEYLCVASNGIPPDESWTVKLLVTFPPLVQAQSETVQA 245
Query: 214 QTGSSVTFQCRVGGDPLPDVLWRR 237
GS C P P++ W +
Sbjct: 246 SVGSMARMVCTTEAWPRPEMGWEK 269
>Z81045-3|CAB02817.3| 280|Caenorhabditis elegans Hypothetical
protein C36F7.4a protein.
Length = 280
Score = 40.7 bits (91), Expect = 0.006
Identities = 24/75 (32%), Positives = 31/75 (41%), Gaps = 1/75 (1%)
Query: 257 LRLDNVILADEGEYSCEAENSVGA-VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCT 315
L L V EY C A N + S + L V PP + +V G++AR CT
Sbjct: 107 LHLTKVSRKHMSEYLCVASNGIPPDESWTVKLLVTFPPLVQAQSETVQASVGSMARMVCT 166
Query: 316 ATGRPEPTMFWSVEG 330
P P M W +G
Sbjct: 167 TEAWPRPEMGWEKDG 181
Score = 36.3 bits (80), Expect = 0.13
Identities = 35/147 (23%), Positives = 62/147 (42%), Gaps = 10/147 (6%)
Query: 83 YWCEATNSYGTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYW 142
Y C A+N S L V + + E+ Q++ G + C P P + W
Sbjct: 120 YLCVASNGIPPDESWTVKLLVT-FPPLVQAQSETVQASVGSMARMVCTT-EAWPRPEMGW 177
Query: 143 KKNGQTLLFDGDSRM-HLVDGGN-----LVIQDARQTDAGRYQCIARNAAGTRESAIATL 196
+K+G+ + + M H V G L I++ + + G Y+C+A+N G S +
Sbjct: 178 EKDGEPVYESNNVAMTHTVSGQYHSVHILEIRNVQSSHFGVYRCVAKNDNGIHHSQVTLN 237
Query: 197 KIHIKPYLITG--PEDVVAQTGSSVTF 221
+I + + PE++ A S +F
Sbjct: 238 QISHNHFTNSNLIPEELRAIQVDSASF 264
Score = 35.5 bits (78), Expect = 0.23
Identities = 21/86 (24%), Positives = 39/86 (45%), Gaps = 8/86 (9%)
Query: 397 PPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGT----- 451
PP++ + SMA CT P P + W +GE + +++ +T+ +
Sbjct: 143 PPLVQAQSETVQASVGSMARMVCTTEAWPRPEMGWEKDGEPVYESNNVAMTHTVSGQYHS 202
Query: 452 ---LVLKDLDKSDSGTYTCVASSRHG 474
L ++++ S G Y CVA + +G
Sbjct: 203 VHILEIRNVQSSHFGVYRCVAKNDNG 228
Score = 32.7 bits (71), Expect = 1.6
Identities = 20/84 (23%), Positives = 30/84 (35%)
Query: 154 DSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA 213
D + + G L + + Y C+A N ES L + P + E V A
Sbjct: 96 DVKASVFHGPVLHLTKVSRKHMSEYLCVASNGIPPDESWTVKLLVTFPPLVQAQSETVQA 155
Query: 214 QTGSSVTFQCRVGGDPLPDVLWRR 237
GS C P P++ W +
Sbjct: 156 SVGSMARMVCTTEAWPRPEMGWEK 179
>U29487-1|AAA68768.1| 253|Caenorhabditis elegans 2 (zwei) ig-domain
protein protein4 protein.
Length = 253
Score = 40.7 bits (91), Expect = 0.006
Identities = 18/58 (31%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 420 TAICTPEPIIAW-YFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
T +C + W + + L++N+ + V ++G LV+K++ D GTYTC+A ++ G+
Sbjct: 180 TLVCRANQQVDWVWMSNDELVKNNDKFTVLSNGDLVIKNIVWDDMGTYTCIARNQFGE 237
Score = 37.5 bits (83), Expect = 0.057
Identities = 47/197 (23%), Positives = 76/197 (38%), Gaps = 29/197 (14%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH---------LVDGGN- 164
ES G+T L C +P ++WK NG+ + + + +VD G
Sbjct: 53 ESALIPGGETYQLRC-DIMSTPAATIHWKFNGKLIQGSNELNVEEKLLNFGKAIVDTGIV 111
Query: 165 ---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-----------PYLITGPED 210
L IQ ++G Y C+ N T E+ +A ++I + P ++ +
Sbjct: 112 ASILTIQCPSAENSGTYSCVGYNGHQTIET-VAEVEIEGEASGCRSNHKSAPEIVFWTDS 170
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270
TG+ T CR D +W S + VL +G L + N++ D G Y
Sbjct: 171 RFEMTGNVATLVCRANQQV--DWVWM-SNDELVKNNDKFTVLSNGDLVIKNIVWDDMGTY 227
Query: 271 SCEAENSVGAVSASGYL 287
+C A N G +L
Sbjct: 228 TCIARNQFGEARQETFL 244
>AF456251-1|AAL59609.1| 253|Caenorhabditis elegans secreted
2-immunoglobulin-domainprotein ZIG-4 protein.
Length = 253
Score = 40.7 bits (91), Expect = 0.006
Identities = 18/58 (31%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Query: 420 TAICTPEPIIAW-YFEGEALIQNHRR-NVTNDGTLVLKDLDKSDSGTYTCVASSRHGK 475
T +C + W + + L++N+ + V ++G LV+K++ D GTYTC+A ++ G+
Sbjct: 180 TLVCRANQQVDWVWMSNDELVKNNDKFTVLSNGDLVIKNIVWDDMGTYTCIARNQFGE 237
Score = 37.5 bits (83), Expect = 0.057
Identities = 47/197 (23%), Positives = 76/197 (38%), Gaps = 29/197 (14%)
Query: 115 ESKQSAQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMH---------LVDGGN- 164
ES G+T L C +P ++WK NG+ + + + +VD G
Sbjct: 53 ESALIPGGETYQLRC-DIMSTPAATIHWKFNGKLIQGSNELNVEEKLLNFGKAIVDTGIV 111
Query: 165 ---LVIQDARQTDAGRYQCIARNAAGTRESAIATLKIHIK-----------PYLITGPED 210
L IQ ++G Y C+ N T E+ +A ++I + P ++ +
Sbjct: 112 ASILTIQCPSAENSGTYSCVGYNGHQTIET-VAEVEIEGEASGCRSNHKSAPEIVFWTDS 170
Query: 211 VVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEY 270
TG+ T CR D +W S + VL +G L + N++ D G Y
Sbjct: 171 RFEMTGNVATLVCRANQQV--DWVWM-SNDELVKNNDKFTVLSNGDLVIKNIVWDDMGTY 227
Query: 271 SCEAENSVGAVSASGYL 287
+C A N G +L
Sbjct: 228 TCIARNQFGEARQETFL 244
>AC087794-1|AAG53701.2| 304|Caenorhabditis elegans Hypothetical
protein Y32G9A.8 protein.
Length = 304
Score = 40.7 bits (91), Expect = 0.006
Identities = 26/80 (32%), Positives = 37/80 (46%), Gaps = 3/80 (3%)
Query: 197 KIHIKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGS 256
K +P+ + GP V A S+ QC + G P P ++W + + GRVK G
Sbjct: 147 KSESEPFTVVGPA-VYAPLDSAARIQCPIVGYPEPQIVWYKDKFPLEIE-GRVK-FTAGV 203
Query: 257 LRLDNVILADEGEYSCEAEN 276
L ++ D G Y CEA N
Sbjct: 204 LSIEGAQEEDAGVYRCEATN 223
Score = 37.1 bits (82), Expect = 0.076
Identities = 34/106 (32%), Positives = 44/106 (41%), Gaps = 8/106 (7%)
Query: 8 SGEAPYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLF 67
S P+ + P V A + C G P P I WYK + + R AG L
Sbjct: 148 SESEPFTVVGPA-VYAPLDSAARIQCPIVGYPEPQIVWYKDKFPLEIEG-RVKFTAGVL- 204
Query: 68 FLRATHGRVHSDAGVYWCEATNSYGTARSRNATLHVAV-LREEFRL 112
+ G DAGVY CEATN + + H AV L +E R+
Sbjct: 205 ---SIEGAQEEDAGVYRCEATNQF-PVQIDGPEQHFAVKLDQELRI 246
Score = 36.7 bits (81), Expect = 0.10
Identities = 23/75 (30%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHRRNVTNDGTLVLKDL 457
P GP+ P+ S A C + PEP I WY + L R T G L ++
Sbjct: 152 PFTVVGPAVYA-PLDSAARIQCPIVGYPEPQIVWYKDKFPLEIEGRVKFT-AGVLSIEGA 209
Query: 458 DKSDSGTYTCVASSR 472
+ D+G Y C A+++
Sbjct: 210 QEEDAGVYRCEATNQ 224
Score = 36.3 bits (80), Expect = 0.13
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 4/58 (6%)
Query: 127 LECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
++C P G PEP + W K+ L +G + G L I+ A++ DAG Y+C A N
Sbjct: 170 IQC-PIVGYPEPQIVWYKDKFPLEIEGRVKF---TAGVLSIEGAQEEDAGVYRCEATN 223
>AC006695-2|AAM48553.1| 724|Caenorhabditis elegans Temporarily
assigned gene nameprotein 58, isoform a protein.
Length = 724
Score = 39.9 bits (89), Expect = 0.011
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAGG 65
AP I+E + Q +L C+ +PS A+ W K V V D ++L G
Sbjct: 415 APKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGV 474
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
L DAG+Y C ATN +GTA +
Sbjct: 475 CELLNPEC--FAEDAGLYKCTATNPHGTAET 503
Score = 34.7 bits (76), Expect = 0.40
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 7/87 (8%)
Query: 112 LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKK---NGQTLLFDGDSRMHLVDGG--NL 165
+EP S G + L C +P V W K N + + + D ++DGG L
Sbjct: 419 VEPLHSASFLDGQAMSLRC-KITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGVCEL 477
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESA 192
+ + DAG Y+C A N GT E+A
Sbjct: 478 LNPECFAEDAGLYKCTATNPHGTAETA 504
Score = 33.9 bits (74), Expect = 0.71
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 135 SPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
S P ++ W N +++L D D R + G N+ + + G Y+C+ RN AG S
Sbjct: 115 SDPPAIFEWFYNEKSVLQDRD-RFQVGHGINISRLKVSRPEQGVYKCVTRNPAGVSTSYG 173
Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTF 221
+ +L + ED+ Q SVT+
Sbjct: 174 YITVNADREHLSSSKEDMRLQRQHSVTY 201
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Query: 429 IAWYFEGEALIQNHRRNVTN--DGT--LVLKDLDKSDSGTYTCVASSRHG 474
++W +G + +N + V DG L ++ DSG YTC A S HG
Sbjct: 571 VSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDSGVYTCTAESEHG 620
>AC006695-1|AAU45229.1| 703|Caenorhabditis elegans Temporarily
assigned gene nameprotein 58, isoform b protein.
Length = 703
Score = 39.9 bits (89), Expect = 0.011
Identities = 29/91 (31%), Positives = 40/91 (43%), Gaps = 7/91 (7%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVS-----DTHRSILPAGG 65
AP I+E + Q +L C+ +PS A+ W K V V D ++L G
Sbjct: 394 APKIVEPLHSASFLDGQAMSLRCKITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGV 453
Query: 66 LFFLRATHGRVHSDAGVYWCEATNSYGTARS 96
L DAG+Y C ATN +GTA +
Sbjct: 454 CELLNPEC--FAEDAGLYKCTATNPHGTAET 482
Score = 34.7 bits (76), Expect = 0.40
Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 7/87 (8%)
Query: 112 LEP-ESKQSAQGDTVVLECLPPRGSPEPNVYWKK---NGQTLLFDGDSRMHLVDGG--NL 165
+EP S G + L C +P V W K N + + + D ++DGG L
Sbjct: 398 VEPLHSASFLDGQAMSLRC-KITANPSAAVVWSKDDVNVEDWVLNKDVTTTVLDGGVCEL 456
Query: 166 VIQDARQTDAGRYQCIARNAAGTRESA 192
+ + DAG Y+C A N GT E+A
Sbjct: 457 LNPECFAEDAGLYKCTATNPHGTAETA 483
Score = 33.9 bits (74), Expect = 0.71
Identities = 25/88 (28%), Positives = 41/88 (46%), Gaps = 2/88 (2%)
Query: 135 SPEPNVY-WKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
S P ++ W N +++L D D R + G N+ + + G Y+C+ RN AG S
Sbjct: 115 SDPPAIFEWFYNEKSVLQDRD-RFQVGHGINISRLKVSRPEQGVYKCVTRNPAGVSTSYG 173
Query: 194 ATLKIHIKPYLITGPEDVVAQTGSSVTF 221
+ +L + ED+ Q SVT+
Sbjct: 174 YITVNADREHLSSSKEDMRLQRQHSVTY 201
Score = 33.1 bits (72), Expect = 1.2
Identities = 17/50 (34%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Query: 429 IAWYFEGEALIQNHRRNVTN--DGT--LVLKDLDKSDSGTYTCVASSRHG 474
++W +G + +N + V DG L ++ DSG YTC A S HG
Sbjct: 550 VSWQKDGMDIYENEKYEVMQFADGAQILTIRAPTNLDSGVYTCTAESEHG 599
>Z68005-3|CAA91990.1| 1227|Caenorhabditis elegans Hypothetical
protein F59F3.1 protein.
Length = 1227
Score = 39.5 bits (88), Expect = 0.014
Identities = 46/178 (25%), Positives = 71/178 (39%), Gaps = 18/178 (10%)
Query: 113 EPESKQSAQGDTVVLECLPPRGSPEPNVYWK----KNGQTLLFDGDSRMHLVDGGN---L 165
EP SK +GD V L C+ P S + +V W+ K+ + + L
Sbjct: 577 EP-SKIIYEGDNVKLTCVFPLDSDDWSVSWRFENSKSSDISSIPTTTETEIKQYSKHLIL 635
Query: 166 VIQDARQTDAGRYQCIARNAAGTR--ESAIATLKIHIKPYLITGPEDVVAQTGSSVTFQ- 222
++D + G Y C+ +N + E++I +K KP + G + V F+
Sbjct: 636 NLRDVTTSFTGTYTCVVKNEDSEKLLETSI-DVKAISKPSITGGNSNAVVIVDYDQYFEI 694
Query: 223 -CRVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVG 279
C + G P P W + G G V D LR+ D+GE+ C A N G
Sbjct: 695 NCNMTGTPPPVYQWFKD--GNPYTHGDV---DGSILRVSRARGEDDGEFHCLATNRAG 747
Score = 36.3 bits (80), Expect = 0.13
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 6/60 (10%)
Query: 134 GSPEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAI 193
G+P P W K+G GD VDG L + AR D G + C+A N AG + ++I
Sbjct: 700 GTPPPVYQWFKDGNPYTH-GD-----VDGSILRVSRARGEDDGEFHCLATNRAGDKLNSI 753
Score = 32.7 bits (71), Expect = 1.6
Identities = 30/115 (26%), Positives = 52/115 (45%), Gaps = 10/115 (8%)
Query: 386 KLTVTSDDDRP--PPIITNGPSNQTLPIKSMAVFP--CTAICTPEPIIAWYFEGEALIQN 441
KL TS D + P IT G SN + + F C TP P+ W+ +G N
Sbjct: 659 KLLETSIDVKAISKPSITGGNSNAVVIVDYDQYFEINCNMTGTPPPVYQWFKDG-----N 713
Query: 442 HRRNVTNDGTLV-LKDLDKSDSGTYTCVASSRHGKYVWSGALLVDSPINPNIHFF 495
+ DG+++ + D G + C+A++R G + S + V++ ++ F+
Sbjct: 714 PYTHGDVDGSILRVSRARGEDDGEFHCLATNRAGDKLNSIEVQVNNAPKGSLFFY 768
Score = 31.1 bits (67), Expect = 5.0
Identities = 24/72 (33%), Positives = 32/72 (44%), Gaps = 8/72 (11%)
Query: 21 VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLRATHGRVHSDA 80
V V Q +NC G+P P +W+K G TH + G + LR + R D
Sbjct: 684 VIVDYDQYFEINCNMTGTPPPVYQWFKDG---NPYTHGDV--DGSI--LRVSRARGEDD- 735
Query: 81 GVYWCEATNSYG 92
G + C ATN G
Sbjct: 736 GEFHCLATNRAG 747
>AL023843-1|CAA19522.2| 260|Caenorhabditis elegans Hypothetical
protein Y48A6A.1 protein.
Length = 260
Score = 38.7 bits (86), Expect = 0.025
Identities = 54/204 (26%), Positives = 79/204 (38%), Gaps = 32/204 (15%)
Query: 15 IEQPLD-VTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSD--THRSILPAGGLFFLRA 71
I++PL+ + R L C SP P I WY G V S H L +
Sbjct: 47 IDKPLENIKANRGDSLVLRCAFYASPQPTIVWYHRGKRVDSHPAAHFETLLSATNLGQSV 106
Query: 72 THGRVHSD------AGVYWCEATN--SYGTARSRNATLHVAV---------LREEFRLEP 114
+ D AG Y+CEAT+ + S T++ A +R+ P
Sbjct: 107 VESALRIDCLDERTAGEYFCEATSPCTQPVVTSSTVTINKAPKSITGTCKSIRQPLESPP 166
Query: 115 E------SKQSAQGDTVVLECLPPRGSPEPNVYWKK--NGQTL-LFDGDSR-MHLVDGGN 164
S+ G L C RG P P W K ++L DG MHL +G
Sbjct: 167 IVSDFTLSRIELPGGVAQLACRV-RGVPTPKTKWFKIEEDESLSTIDGQPNYMHLSNGDL 225
Query: 165 LVIQDARQTDAGRYQCIARNAAGT 188
L++ D +T + ++C+A N G+
Sbjct: 226 LIVGD-EETISESFRCVASNPLGS 248
>Z47808-11|CAD36487.1| 928|Caenorhabditis elegans Hypothetical
protein C01G6.8a protein.
Length = 928
Score = 37.9 bits (84), Expect = 0.043
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 3/105 (2%)
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
+V + G + + TS RP +T+ N T F C A+ TP
Sbjct: 10 LVIEPADDEGLHYGNASMEGTSTGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKF 69
Query: 430 AWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
W + + R R+ N LV+ LD DSG Y C+ S+
Sbjct: 70 IWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVLDSGYYQCIVSN 114
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 201 KPYL-ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSL 257
+PY+ +T + +G V F+C G P +W ++ G RVK+ D + S
Sbjct: 35 RPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTK-RVKIRDKENSS 93
Query: 258 RL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLS 298
RL + + D G Y C N +V+ + L V + P ++ LS
Sbjct: 94 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVPDAVKLS 137
Score = 31.1 bits (67), Expect = 5.0
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%)
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAG 176
+ GD V +C G+P W KN + + R+ + D N LVI D+G
Sbjct: 50 SSGDEVRFKC-EALGTPPLKFIWLKNNGPV--EKTKRVKIRDKENSSRLVITQLDVLDSG 106
Query: 177 RYQCIARNAAGT 188
YQCI N A +
Sbjct: 107 YYQCIVSNPAAS 118
>Z35595-12|CAD36478.1| 928|Caenorhabditis elegans Hypothetical
protein C01G6.8a protein.
Length = 928
Score = 37.9 bits (84), Expect = 0.043
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 3/105 (2%)
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
+V + G + + TS RP +T+ N T F C A+ TP
Sbjct: 10 LVIEPADDEGLHYGNASMEGTSTGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKF 69
Query: 430 AWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
W + + R R+ N LV+ LD DSG Y C+ S+
Sbjct: 70 IWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVLDSGYYQCIVSN 114
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 201 KPYL-ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSL 257
+PY+ +T + +G V F+C G P +W ++ G RVK+ D + S
Sbjct: 35 RPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTK-RVKIRDKENSS 93
Query: 258 RL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLS 298
RL + + D G Y C N +V+ + L V + P ++ LS
Sbjct: 94 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVPDAVKLS 137
Score = 31.1 bits (67), Expect = 5.0
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%)
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAG 176
+ GD V +C G+P W KN + + R+ + D N LVI D+G
Sbjct: 50 SSGDEVRFKC-EALGTPPLKFIWLKNNGPV--EKTKRVKIRDKENSSRLVITQLDVLDSG 106
Query: 177 RYQCIARNAAGT 188
YQCI N A +
Sbjct: 107 YYQCIVSNPAAS 118
>AJ132946-1|CAC29084.1| 928|Caenorhabditis elegans receptor
tyrosine kinase protein.
Length = 928
Score = 37.9 bits (84), Expect = 0.043
Identities = 28/105 (26%), Positives = 41/105 (39%), Gaps = 3/105 (2%)
Query: 370 IVCSAVNYAGSSFVRGKLTVTSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPII 429
+V + G + + TS RP +T+ N T F C A+ TP
Sbjct: 10 LVIEPADDEGLHYGNASMEGTSTGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKF 69
Query: 430 AWYFEGEALIQNHR---RNVTNDGTLVLKDLDKSDSGTYTCVASS 471
W + + R R+ N LV+ LD DSG Y C+ S+
Sbjct: 70 IWLKNNGPVEKTKRVKIRDKENSSRLVITQLDVLDSGYYQCIVSN 114
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 201 KPYL-ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSL 257
+PY+ +T + +G V F+C G P +W ++ G RVK+ D + S
Sbjct: 35 RPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTK-RVKIRDKENSS 93
Query: 258 RL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLS 298
RL + + D G Y C N +V+ + L V + P ++ LS
Sbjct: 94 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVPDAVKLS 137
Score = 31.1 bits (67), Expect = 5.0
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%)
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAG 176
+ GD V +C G+P W KN + + R+ + D N LVI D+G
Sbjct: 50 SSGDEVRFKC-EALGTPPLKFIWLKNNGPV--EKTKRVKIRDKENSSRLVITQLDVLDSG 106
Query: 177 RYQCIARNAAGT 188
YQCI N A +
Sbjct: 107 YYQCIVSNPAAS 118
>Z54218-4|CAA90958.1| 1367|Caenorhabditis elegans Hypothetical
protein F44G4.8 protein.
Length = 1367
Score = 37.1 bits (82), Expect = 0.076
Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM---VAINTTVHQATSLIMTN 799
LN+ +V L W PP L NGI+T Y V V + +++ V+ N + H +++
Sbjct: 651 LNSYSVMLTWLPP--ALPNGILTHYAVNVTKIGSDETRTIDVGVSSNRSDH-TVQVVIDE 707
Query: 800 LTSGVSYSVQIAAETIIGLGPFSQKV 825
L G +YS + A T G G S V
Sbjct: 708 LFGGHTYSFSVRAVTEAGFGENSPVV 733
>Z49910-9|CAA90125.1| 1367|Caenorhabditis elegans Hypothetical
protein F44G4.8 protein.
Length = 1367
Score = 37.1 bits (82), Expect = 0.076
Identities = 28/86 (32%), Positives = 42/86 (48%), Gaps = 6/86 (6%)
Query: 743 LNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSM---VAINTTVHQATSLIMTN 799
LN+ +V L W PP L NGI+T Y V V + +++ V+ N + H +++
Sbjct: 651 LNSYSVMLTWLPP--ALPNGILTHYAVNVTKIGSDETRTIDVGVSSNRSDH-TVQVVIDE 707
Query: 800 LTSGVSYSVQIAAETIIGLGPFSQKV 825
L G +YS + A T G G S V
Sbjct: 708 LFGGHTYSFSVRAVTEAGFGENSPVV 733
>Z47808-12|CAB61003.1| 902|Caenorhabditis elegans Hypothetical
protein C01G6.8b protein.
Length = 902
Score = 37.1 bits (82), Expect = 0.076
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 3/85 (3%)
Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR---RNV 446
TS RP +T+ N T F C A+ TP W + + R R+
Sbjct: 4 TSTGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDK 63
Query: 447 TNDGTLVLKDLDKSDSGTYTCVASS 471
N LV+ LD DSG Y C+ S+
Sbjct: 64 ENSSRLVITQLDVLDSGYYQCIVSN 88
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 201 KPYL-ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSL 257
+PY+ +T + +G V F+C G P +W ++ G RVK+ D + S
Sbjct: 9 RPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTK-RVKIRDKENSS 67
Query: 258 RL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLS 298
RL + + D G Y C N +V+ + L V + P ++ LS
Sbjct: 68 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVPDAVKLS 111
Score = 31.1 bits (67), Expect = 5.0
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%)
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAG 176
+ GD V +C G+P W KN + + R+ + D N LVI D+G
Sbjct: 24 SSGDEVRFKC-EALGTPPLKFIWLKNNGPV--EKTKRVKIRDKENSSRLVITQLDVLDSG 80
Query: 177 RYQCIARNAAGT 188
YQCI N A +
Sbjct: 81 YYQCIVSNPAAS 92
>Z35595-13|CAA84639.2| 902|Caenorhabditis elegans Hypothetical
protein C01G6.8b protein.
Length = 902
Score = 37.1 bits (82), Expect = 0.076
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 3/85 (3%)
Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR---RNV 446
TS RP +T+ N T F C A+ TP W + + R R+
Sbjct: 4 TSTGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDK 63
Query: 447 TNDGTLVLKDLDKSDSGTYTCVASS 471
N LV+ LD DSG Y C+ S+
Sbjct: 64 ENSSRLVITQLDVLDSGYYQCIVSN 88
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 201 KPYL-ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSL 257
+PY+ +T + +G V F+C G P +W ++ G RVK+ D + S
Sbjct: 9 RPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTK-RVKIRDKENSS 67
Query: 258 RL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLS 298
RL + + D G Y C N +V+ + L V + P ++ LS
Sbjct: 68 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVPDAVKLS 111
Score = 31.1 bits (67), Expect = 5.0
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%)
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAG 176
+ GD V +C G+P W KN + + R+ + D N LVI D+G
Sbjct: 24 SSGDEVRFKC-EALGTPPLKFIWLKNNGPV--EKTKRVKIRDKENSSRLVITQLDVLDSG 80
Query: 177 RYQCIARNAAGT 188
YQCI N A +
Sbjct: 81 YYQCIVSNPAAS 92
>AJ132947-1|CAC29085.1| 902|Caenorhabditis elegans receptor
tyrosine kinase protein.
Length = 902
Score = 37.1 bits (82), Expect = 0.076
Identities = 26/85 (30%), Positives = 35/85 (41%), Gaps = 3/85 (3%)
Query: 390 TSDDDRPPPIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFEGEALIQNHR---RNV 446
TS RP +T+ N T F C A+ TP W + + R R+
Sbjct: 4 TSTGQRPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTKRVKIRDK 63
Query: 447 TNDGTLVLKDLDKSDSGTYTCVASS 471
N LV+ LD DSG Y C+ S+
Sbjct: 64 ENSSRLVITQLDVLDSGYYQCIVSN 88
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/104 (27%), Positives = 48/104 (46%), Gaps = 7/104 (6%)
Query: 201 KPYL-ITGP-EDVVAQTGSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRVKVLD-DGSL 257
+PY+ +T + +G V F+C G P +W ++ G RVK+ D + S
Sbjct: 9 RPYIRLTSQLRNATKSSGDEVRFKCEALGTPPLKFIWLKNNGPVEKTK-RVKIRDKENSS 67
Query: 258 RL--DNVILADEGEYSCEAENSVGAVSASGYLTVYD-PPSINLS 298
RL + + D G Y C N +V+ + L V + P ++ LS
Sbjct: 68 RLVITQLDVLDSGYYQCIVSNPAASVNTTSVLRVNNVPDAVKLS 111
Score = 31.1 bits (67), Expect = 5.0
Identities = 23/72 (31%), Positives = 32/72 (44%), Gaps = 6/72 (8%)
Query: 120 AQGDTVVLECLPPRGSPEPNVYWKKNGQTLLFDGDSRMHLVDGGN---LVIQDARQTDAG 176
+ GD V +C G+P W KN + + R+ + D N LVI D+G
Sbjct: 24 SSGDEVRFKC-EALGTPPLKFIWLKNNGPV--EKTKRVKIRDKENSSRLVITQLDVLDSG 80
Query: 177 RYQCIARNAAGT 188
YQCI N A +
Sbjct: 81 YYQCIVSNPAAS 92
>U28409-1|AAC46592.3| 231|Caenorhabditis elegans Hypothetical
protein T25D10.2 protein.
Length = 231
Score = 36.3 bits (80), Expect = 0.13
Identities = 29/112 (25%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query: 79 DAGVYWCEATNS--YGTA-RSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGS 135
D G Y+C+ N +G + + A + E+ +LEP G ++VL C P+
Sbjct: 101 DEGNYYCQRENDSKWGEVFQLKIAYVDEISQNEKIKLEPNVP--TLGRSLVLHCPIPKAY 158
Query: 136 PEPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAG 187
P P V W N + + G L+I G ++C N AG
Sbjct: 159 PPPKVTWTVNSLPISHISSDYV-AFPNGTLIISHFSYHHFGYFECNINNFAG 209
>AF078787-10|AAC26956.1| 352|Caenorhabditis elegans Hypothetical
protein T17A3.10 protein.
Length = 352
Score = 36.3 bits (80), Expect = 0.13
Identities = 34/143 (23%), Positives = 53/143 (37%), Gaps = 24/143 (16%)
Query: 117 KQSAQGDTVVLECLPPRGSPEPNVYWKKNGQ--------TLLFDGDSRMHLVDGGNLVIQ 168
K + DTV L C P + V W+ T L DG+S+ H+ N+
Sbjct: 141 KSVYEQDTVNLFCAIPHSAINWKVSWRLENSNSTSDLSVTTLIDGNSKYHVTTVKNI--- 197
Query: 169 DARQTDAGRYQCIARNAAGTRESAIATLKIHIKPYLITGPEDVVA--------QTGSSVT 220
T +G Y C+ + I +KP T PE + + ++ +
Sbjct: 198 ----TKSGVYTCVIEADKFKERRQLLETVIKVKP-ASTRPEPIKSSKMAIPNCKSSIEIE 252
Query: 221 FQCRVGGDPLPDVLWRRSAGGGN 243
QC + G PLP+ W G+
Sbjct: 253 IQCNITGHPLPEYSWVTDESSGS 275
>U64857-1|AAC25868.1| 2167|Caenorhabditis elegans Hypothetical protein
C37C3.6b protein.
Length = 2167
Score = 35.5 bits (78), Expect = 0.23
Identities = 17/41 (41%), Positives = 21/41 (51%)
Query: 429 IAWYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCVA 469
I WY G L R ND TL + D +D+G YTC+A
Sbjct: 2014 ITWYKNGGLLQFGSRITEENDDTLEIVDALTADAGVYTCIA 2054
Score = 31.9 bits (69), Expect = 2.9
Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
Query: 140 VYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARNAAGTRESAIATLK 197
+ W KNG L F SR+ + L I DA DAG Y CIA + E +K
Sbjct: 2014 ITWYKNGGLLQFG--SRITEENDDTLEIVDALTADAGVYTCIAGQDSTMSEGVEVVIK 2069
>AF216968-1|AAF60253.2| 658|Caenorhabditis elegans semaphorin-2a
protein.
Length = 658
Score = 35.1 bits (77), Expect = 0.31
Identities = 16/46 (34%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
N W+K+G+++ + R + G LV+ DA+ DAG Y+C+ N
Sbjct: 553 NGVWQKDGRSV--ESGQRHVVTRNGELVVLDAQLEDAGTYECLRDN 596
Score = 34.3 bits (75), Expect = 0.53
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
W +G ++ R VT +G LV+ D D+GTY C+
Sbjct: 556 WQKDGRSVESGQRHVVTRNGELVVLDAQLEDAGTYECL 593
>AC025726-1|AAK73921.1| 658|Caenorhabditis elegans Male abnormal
protein 20, isoform a protein.
Length = 658
Score = 35.1 bits (77), Expect = 0.31
Identities = 16/46 (34%), Positives = 27/46 (58%), Gaps = 2/46 (4%)
Query: 139 NVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDARQTDAGRYQCIARN 184
N W+K+G+++ + R + G LV+ DA+ DAG Y+C+ N
Sbjct: 553 NGVWQKDGRSV--ESGQRHVVTRNGELVVLDAQLEDAGTYECLRDN 596
Score = 34.3 bits (75), Expect = 0.53
Identities = 14/38 (36%), Positives = 21/38 (55%)
Query: 431 WYFEGEALIQNHRRNVTNDGTLVLKDLDKSDSGTYTCV 468
W +G ++ R VT +G LV+ D D+GTY C+
Sbjct: 556 WQKDGRSVESGQRHVVTRNGELVVLDAQLEDAGTYECL 593
>Z54236-7|CAA90982.1| 1471|Caenorhabditis elegans Hypothetical
protein C27B7.7 protein.
Length = 1471
Score = 34.7 bits (76), Expect = 0.40
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 9/80 (11%)
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRR-----NVTNDGTLVLKDLDKS---DSGTYTCVAS 470
CT + +P PII W + ++ I+N N+ D T V+ + ++ +SG TC+A+
Sbjct: 892 CTGMGSPAPIITWEWMNKS-IENGTEGWNILNIQIDDTTVVSKITRNNIRESGDLTCLAN 950
Query: 471 SRHGKYVWSGALLVDSPINP 490
+ G S + V P NP
Sbjct: 951 NNEGSSSASVEIRVLGPGNP 970
Score = 31.9 bits (69), Expect = 2.9
Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 4/128 (3%)
Query: 704 EFFLIPFYKKFEG-KPSNSRVAQ-TLDDVPDGPPINIEMFILNTTTVHLKWSPPELQLQ- 760
E+F+ K G P++S ++ TL+ PD PP N+++ I V + W+ P +
Sbjct: 619 EYFVCVRAKNAAGIGPTSSLISFITLNGGPDSPPDNLKVLINEANQVIVYWNTPNSTTEV 678
Query: 761 NGIITGYNVVVNWL-DVPANKSMVAINTTVHQATSLIMTNLTSGVSYSVQIAAETIIGLG 819
G + Y ++ D N V +N + + L Y V+I+ + G
Sbjct: 679 TGYLIYYTRDLSLSNDDYKNWQFVEMNNNSTRYKFDLSVGLKPKTFYRVRISGKNSHADG 738
Query: 820 PFSQKVYF 827
P S+ V F
Sbjct: 739 PASEVVEF 746
>Z83123-13|CAB05615.2| 1208|Caenorhabditis elegans Hypothetical
protein C25G4.10 protein.
Length = 1208
Score = 34.3 bits (75), Expect = 0.53
Identities = 25/112 (22%), Positives = 54/112 (48%), Gaps = 7/112 (6%)
Query: 85 CEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
C +++ G R A H+ + R+ ++ + + +V +EC+ G +P + ++
Sbjct: 776 CAVSDTDG--RQHVAMKHLVLERKASVTMKKDKIRVLDDQSVEIECIYRGGGLDPKISFE 833
Query: 144 KNGQTLLFDGDSRMHLVDGGNLV---IQDARQTDAGRYQCIARNAAGTRESA 192
K+G+ G + + G + I+ +Q DAG Y+C+ ++ G+R A
Sbjct: 834 KDGKKAS-RGFLNLKKTEAGYVAKWHIRKVKQEDAGFYKCVVTSSDGSRVEA 884
>Z83123-2|CAB05606.1| 1014|Caenorhabditis elegans Hypothetical
protein T04A11.3 protein.
Length = 1014
Score = 34.3 bits (75), Expect = 0.53
Identities = 25/112 (22%), Positives = 54/112 (48%), Gaps = 7/112 (6%)
Query: 85 CEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
C +++ G R A H+ + R+ ++ + + +V +EC+ G +P + ++
Sbjct: 582 CAVSDTDG--RQHVAMKHLVLERKASVTMKKDKIRVLDDQSVEIECIYRGGGLDPKISFE 639
Query: 144 KNGQTLLFDGDSRMHLVDGGNLV---IQDARQTDAGRYQCIARNAAGTRESA 192
K+G+ G + + G + I+ +Q DAG Y+C+ ++ G+R A
Sbjct: 640 KDGKKAS-RGFLNLKKTEAGYVAKWHIRKVKQEDAGFYKCVVTSSDGSRVEA 690
>Z70680-10|CAA94577.2| 1208|Caenorhabditis elegans Hypothetical
protein C25G4.10 protein.
Length = 1208
Score = 34.3 bits (75), Expect = 0.53
Identities = 25/112 (22%), Positives = 54/112 (48%), Gaps = 7/112 (6%)
Query: 85 CEATNSYGTARSRNATLHVAVLRE-EFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWK 143
C +++ G R A H+ + R+ ++ + + +V +EC+ G +P + ++
Sbjct: 776 CAVSDTDG--RQHVAMKHLVLERKASVTMKKDKIRVLDDQSVEIECIYRGGGLDPKISFE 833
Query: 144 KNGQTLLFDGDSRMHLVDGGNLV---IQDARQTDAGRYQCIARNAAGTRESA 192
K+G+ G + + G + I+ +Q DAG Y+C+ ++ G+R A
Sbjct: 834 KDGKKAS-RGFLNLKKTEAGYVAKWHIRKVKQEDAGFYKCVVTSSDGSRVEA 884
>U49956-4|AAK77620.1| 1117|Caenorhabditis elegans Variable abnormal
morphology protein1, isoform a protein.
Length = 1117
Score = 34.3 bits (75), Expect = 0.53
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 6/58 (10%)
Query: 494 FFRAAD-VSSLP--GPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSR 545
+FRA D + S+P PP++PI + +T TS LSW++ + +G + Y+V+ R
Sbjct: 326 YFRAEDELISMPCTQPPSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGR 383
>U49956-3|AAK77621.1| 1122|Caenorhabditis elegans Variable abnormal
morphology protein1, isoform b protein.
Length = 1122
Score = 34.3 bits (75), Expect = 0.53
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 6/58 (10%)
Query: 494 FFRAAD-VSSLP--GPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSR 545
+FRA D + S+P PP++PI + +T TS LSW++ + +G + Y+V+ R
Sbjct: 326 YFRAEDELISMPCTQPPSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGR 383
>AF040269-1|AAC38970.1| 1122|Caenorhabditis elegans Eph receptor
tyrosine kinase protein.
Length = 1122
Score = 34.3 bits (75), Expect = 0.53
Identities = 20/58 (34%), Positives = 34/58 (58%), Gaps = 6/58 (10%)
Query: 494 FFRAAD-VSSLP--GPPTKPI---THNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSR 545
+FRA D + S+P PP++PI + +T TS LSW++ + +G + Y+V+ R
Sbjct: 326 YFRAEDELISMPCTQPPSRPIKLVANAITATSTRLSWNEPSSLGGRPEIWYEVKCSGR 383
>AF456252-1|AAL59610.1| 259|Caenorhabditis elegans secreted
2-immunoglobulin-domainprotein ZIG-5 protein.
Length = 259
Score = 33.9 bits (74), Expect = 0.71
Identities = 30/101 (29%), Positives = 45/101 (44%), Gaps = 9/101 (8%)
Query: 92 GTARSRNATLHVAVLREEFRLEPESKQSAQGDTVVLECLPPRGSPEPNVYWKK--NGQTL 149
GT +S L + +F L S+ G L C RG P P W K ++L
Sbjct: 152 GTCKSIRQPLESPPIVSDFTL---SRIELPGGVAQLACRV-RGVPTPKTKWFKIEEDESL 207
Query: 150 -LFDGDSR-MHLVDGGNLVIQDARQTDAGRYQCIARNAAGT 188
DG MHL +G L++ D +T + ++C+A N G+
Sbjct: 208 STIDGQPNYMHLSNGDLLIVGD-EETISESFRCVASNPLGS 247
>AL032639-10|CAA21634.1| 108|Caenorhabditis elegans Hypothetical
protein Y38F1A.9 protein.
Length = 108
Score = 33.5 bits (73), Expect = 0.93
Identities = 21/85 (24%), Positives = 37/85 (43%), Gaps = 7/85 (8%)
Query: 398 PIITNGPSNQTLPIKSMAVFPCTAICTPEPIIAWYFE-----GEALIQNHRRNVTN-DGT 451
P PS P S+ +F C P+P + W+ + G+ + ++ V T
Sbjct: 5 PFFEKAPSLIIAPDGSV-LFECICNANPQPTVKWFLKDKELTGDRYVSKIKKMVGKFTVT 63
Query: 452 LVLKDLDKSDSGTYTCVASSRHGKY 476
L +K+ + D G Y A++ HG +
Sbjct: 64 LHIKNPTQEDQGVYKVTATNTHGSH 88
Score = 31.9 bits (69), Expect = 2.9
Identities = 23/88 (26%), Positives = 40/88 (45%), Gaps = 6/88 (6%)
Query: 200 IKPYLITGPEDVVAQTGSSVTFQCRVGGDPLPDVLW--RRSAGGGNMPLGRVKVLDDG-- 255
+ P+ P ++A GS V F+C +P P V W + G+ + ++K +
Sbjct: 3 LAPFFEKAPSLIIAPDGS-VLFECICNANPQPTVKWFLKDKELTGDRYVSKIKKMVGKFT 61
Query: 256 -SLRLDNVILADEGEYSCEAENSVGAVS 282
+L + N D+G Y A N+ G+ S
Sbjct: 62 VTLHIKNPTQEDQGVYKVTATNTHGSHS 89
Score = 31.9 bits (69), Expect = 2.9
Identities = 22/103 (21%), Positives = 41/103 (39%), Gaps = 3/103 (2%)
Query: 11 APYIIEQPLDVTVARHQPATLNCRAGGSPSPAIRWYKGGVLVVSDTHRSILPAGGLFFLR 70
AP+ + P + +A C +P P ++W+ + D + S + F
Sbjct: 4 APFFEKAP-SLIIAPDGSVLFECICNANPQPTVKWFLKDKELTGDRYVSKIKKMVGKFTV 62
Query: 71 ATHGR--VHSDAGVYWCEATNSYGTARSRNATLHVAVLREEFR 111
H + D GVY ATN++G+ ++ +E F+
Sbjct: 63 TLHIKNPTQEDQGVYKVTATNTHGSHSVEQQYIYKCTGKEVFK 105
>Z69634-7|CAD01081.2| 490|Caenorhabditis elegans Hypothetical protein
B0001.8 protein.
Length = 490
Score = 32.7 bits (71), Expect = 1.6
Identities = 39/148 (26%), Positives = 68/148 (45%), Gaps = 14/148 (9%)
Query: 1016 PPGGKNVDTFDNRYGADEELYPASNGGYYNRNVY---SEKYFQGHPNVLKFYDLPSMEKS 1072
P G ++ + N+Y + P N G N+N Y S+ G P+ + +P+ E +
Sbjct: 211 PRGSRHSRSPINQYSDERNRSPRYNDGRSNQNDYGNTSQYSRNGSPDRSR-RQIPN-EHN 268
Query: 1073 QKAQLRYNQSLEDRKADKNSKADVTQSLIGRTYGISSRKNSESETTYRAFGEFESD-EES 1131
+ + LR ++S E R++ T+S G + +R NS TT + +D E+S
Sbjct: 269 RPSNLRRSRSAERRRSP-------TRSYRGASPRNLARSNSGLSTTSKISRAPTTDSEDS 321
Query: 1132 YDHNGGYDELQAMQSQR-QRPQHQYERP 1158
D G++ + R Q+P + ERP
Sbjct: 322 DDDAAGFNRTKETPILRDQKPTAKKERP 349
>AC084152-4|AAR85899.1| 753|Caenorhabditis elegans Hypothetical
protein Y102A11A.2b protein.
Length = 753
Score = 32.7 bits (71), Expect = 1.6
Identities = 20/98 (20%), Positives = 47/98 (47%), Gaps = 3/98 (3%)
Query: 1078 RYNQSLEDRKADKNSKADVTQSLIGRTYGISSRKNSESETTYRAFGEFESDEESYDHNGG 1137
++ ++LE+R D ++ +L+GR S KN+E+ T+ + E E +D
Sbjct: 552 KFIRNLEERIKDSRDSKNLNGALVGRQINQSLAKNAENLTSAQT-DEDNGQVEGHDGAND 610
Query: 1138 YDELQAMQ--SQRQRPQHQYERPNFDNDGTRTLARLTS 1173
++ Q ++++ +H Y+ ++D+ + + S
Sbjct: 611 QKNMKTDQNANRKKYAEHYYDFDDYDDSELHSTTSMNS 648
>AC024214-10|AAF36080.1| 778|Caenorhabditis elegans Calpain family
protein 7 protein.
Length = 778
Score = 32.7 bits (71), Expect = 1.6
Identities = 15/87 (17%), Positives = 40/87 (45%), Gaps = 2/87 (2%)
Query: 1079 YNQSLEDRKADKNSKADVTQSLIGRTYGISSRKNSESETTYRAFGE--FESDEESYDHNG 1136
Y+ + ++ D ++ + G+ YG ++ + + +G ++ + + D+ G
Sbjct: 36 YDDQNQFQEQDYGNEQNYGNQDYGQGYGNQQDYGNQQDYQQQNYGGGGYDDEYQQQDYQG 95
Query: 1137 GYDELQAMQSQRQRPQHQYERPNFDND 1163
GYD+ + + Q + E+ ++ ND
Sbjct: 96 GYDDSEQYEEQEEAEPEPEEQEDYSND 122
>Z83244-6|CAD18877.1| 502|Caenorhabditis elegans Hypothetical protein
W06F12.2c protein.
Length = 502
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 13/97 (13%)
Query: 1070 EKSQKAQLRYNQSLEDRKADKNSKADVTQSLIGRTYGISSRKNSESETTYRAFGEFESDE 1129
++ Q+++ RY+ S+ D +AD+ + + +S R G S R +S+ R + E D
Sbjct: 375 KRRQRSRSRYDDSVYDSEADRERERERRRSKRNRQGG-SQRSSSKKHRDDRRDRDRERDR 433
Query: 1130 ESYDHNGGYDELQAMQSQRQRPQHQYERPNFDNDGTR 1166
D N R+R + + ER N DN+ R
Sbjct: 434 NDRDRN------------REREREERERENRDNERGR 458
>Z83244-5|CAB54315.1| 568|Caenorhabditis elegans Hypothetical protein
W06F12.2b protein.
Length = 568
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 13/97 (13%)
Query: 1070 EKSQKAQLRYNQSLEDRKADKNSKADVTQSLIGRTYGISSRKNSESETTYRAFGEFESDE 1129
++ Q+++ RY+ S+ D +AD+ + + +S R G S R +S+ R + E D
Sbjct: 375 KRRQRSRSRYDDSVYDSEADRERERERRRSKRNRQGG-SQRSSSKKHRDDRRDRDRERDR 433
Query: 1130 ESYDHNGGYDELQAMQSQRQRPQHQYERPNFDNDGTR 1166
D N R+R + + ER N DN+ R
Sbjct: 434 NDRDRN------------REREREERERENRDNERGR 458
>Z83244-4|CAB54314.1| 562|Caenorhabditis elegans Hypothetical protein
W06F12.2a protein.
Length = 562
Score = 32.3 bits (70), Expect = 2.2
Identities = 26/97 (26%), Positives = 45/97 (46%), Gaps = 13/97 (13%)
Query: 1070 EKSQKAQLRYNQSLEDRKADKNSKADVTQSLIGRTYGISSRKNSESETTYRAFGEFESDE 1129
++ Q+++ RY+ S+ D +AD+ + + +S R G S R +S+ R + E D
Sbjct: 369 KRRQRSRSRYDDSVYDSEADRERERERRRSKRNRQGG-SQRSSSKKHRDDRRDRDRERDR 427
Query: 1130 ESYDHNGGYDELQAMQSQRQRPQHQYERPNFDNDGTR 1166
D N R+R + + ER N DN+ R
Sbjct: 428 NDRDRN------------REREREERERENRDNERGR 452
>AC006607-2|AAF60372.1| 137|Caenorhabditis elegans One ig domain
protein 1 protein.
Length = 137
Score = 32.3 bits (70), Expect = 2.2
Identities = 22/66 (33%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Query: 31 LNCRAGGSPSPAIRWYKGGVLVVSDTHRSI---LPAGGLFFLRATHGRVHSDAGVYWCEA 87
L C + G+P P I WY GV V D +R+I + + D G Y C A
Sbjct: 61 LFCESSGNPRPQIVWYHRGVEVNPDHNRTIRFSIHGDTVSSHLEVDPTSIGDKGEYECVA 120
Query: 88 TNSYGT 93
TN G+
Sbjct: 121 TNLKGS 126
Score = 31.5 bits (68), Expect = 3.8
Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 7/66 (10%)
Query: 419 CTAICTPEPIIAWYFEGEALIQNHRRNV-------TNDGTLVLKDLDKSDSGTYTCVASS 471
C + P P I WY G + +H R + T L + D G Y CVA++
Sbjct: 63 CESSGNPRPQIVWYHRGVEVNPDHNRTIRFSIHGDTVSSHLEVDPTSIGDKGEYECVATN 122
Query: 472 RHGKYV 477
G V
Sbjct: 123 LKGSRV 128
Score = 30.3 bits (65), Expect = 8.7
Identities = 22/81 (27%), Positives = 32/81 (39%), Gaps = 7/81 (8%)
Query: 216 GSSVTFQCRVGGDPLPDVLWRRSAGGGNMPLGRV---KVLDD---GSLRLDNVILADEGE 269
G + C G+P P ++W N R + D L +D + D+GE
Sbjct: 56 GYKLKLFCESSGNPRPQIVWYHRGVEVNPDHNRTIRFSIHGDTVSSHLEVDPTSIGDKGE 115
Query: 270 YSCEAENSVGAVSASGYLTVY 290
Y C A N G+ +LT Y
Sbjct: 116 YECVATNLKGS-RVKKFLTDY 135
>AC024753-2|AAF60457.2| 561|Caenorhabditis elegans Hypothetical
protein Y23H5B.5 protein.
Length = 561
Score = 31.9 bits (69), Expect = 2.9
Identities = 18/61 (29%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 1043 YYNRNVYSEKYFQGHPNVLK-FYDLPSMEKSQKAQLRYNQSLEDRKADKNSKADVTQSLI 1101
+ N N+Y +YF V+ F+D+ ++EK K +++ QSL + + SLI
Sbjct: 443 FLNHNLYKAQYFSTLKEVVNAFFDVYALEKLDKDVVKHVQSLRGSLGRELEVQKMISSLI 502
Query: 1102 G 1102
G
Sbjct: 503 G 503
>U80846-3|AAC70890.1| 2232|Caenorhabditis elegans Hypothetical protein
K06A9.1b protein.
Length = 2232
Score = 31.5 bits (68), Expect = 3.8
Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 3/118 (2%)
Query: 508 TKPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETLSGNNTPRNSRGWVVIARRV 567
T P T++ T ++VT+ S + + +SS Q ++ + + S +T +S +
Sbjct: 1456 TSPSTNSQTGSTVTMGSSSTSGVSTSSASSTQPQMSTSQGSSAGSTVASSTASPAASSTA 1515
Query: 568 HQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVGDDSNSLWEGTGVSNSTE 625
+ + S G I +E+S S S +VT+G S S T ++ST+
Sbjct: 1516 PSSTGTMSSTSSGTVGSTI--SESSTTASASSQTGSTVTMGSSSTS-GVSTSSASSTQ 1570
>Z81042-1|CAB02795.1| 1657|Caenorhabditis elegans Hypothetical protein
C27H6.1 protein.
Length = 1657
Score = 31.1 bits (67), Expect = 5.0
Identities = 37/143 (25%), Positives = 58/143 (40%), Gaps = 17/143 (11%)
Query: 1027 NRYGADEELYPASNGGYYNRNVYSEKYFQGHPNVLKFYDLPSMEKSQKAQLRYNQSLEDR 1086
N YGA+ A N Y+ + Y ++G+ + YD E+SQ+ Q + E
Sbjct: 489 NAYGAEAA---ADNSQEYDYSAYGG--YEGYLAACRAYD----EESQQPQYGETVATEAY 539
Query: 1087 KADKN--SKADVTQSLIGRTYGISSRKNSESE----TTYRAFGEFESDEESYDHNGGYDE 1140
D + D +G T S+ S E +T +G+ + + YDHN Y +
Sbjct: 540 SQDYGYEQQGDYHHEGVGATDENSTSAISGYEQNGASTSLGYGDAQG-YDGYDHNASYYQ 598
Query: 1141 LQAMQSQRQRPQHQYERPNFDND 1163
Q Q Q H+YE + D
Sbjct: 599 GQEYQ-QEYYQNHKYENSQYQVD 620
>U42834-3|AAA83583.2| 860|Caenorhabditis elegans Hypothetical protein
F28B4.2 protein.
Length = 860
Score = 31.1 bits (67), Expect = 5.0
Identities = 20/76 (26%), Positives = 40/76 (52%), Gaps = 6/76 (7%)
Query: 1063 FYDLPSMEKSQKAQLRYNQSLEDRKADKNSKADVTQSLIGRTYGISSRKNS--ESETTYR 1120
F+ LP +++++ +N+SLE K +S D++ S I + + +++ ++ T R
Sbjct: 478 FFFLPCLDENEC----FNRSLEIEKPPMHSTPDLSSSRINSSMLSNGSQSTPVKNSTLSR 533
Query: 1121 AFGEFESDEESYDHNG 1136
F + E+S HNG
Sbjct: 534 LFNSSRTSEDSGSHNG 549
>AF132883-1|AAD25092.1| 925|Caenorhabditis elegans UNC-52/Perlecan
protein.
Length = 925
Score = 31.1 bits (67), Expect = 5.0
Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 13/154 (8%)
Query: 211 VVAQTGSSVTFQC--RVGGDPLPDVLWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEG 268
VV G C + P V+W + G ++P G ++ G L L +V DEG
Sbjct: 5 VVYTVGQPAYLSCIGKTETKPNQSVVWTKEEG--DLPSG--SRVEQGVLMLPSVHRDDEG 60
Query: 269 EYSCE---AENSVGA---VSASGYLTVYDPPSINLSPNSVNVESGNVARFTCTATGRPEP 322
Y+CE EN V + + ++ V D I L P S + E N+ T P+
Sbjct: 61 SYTCEIVKEENPVFSTVDLQIDDFIPVIDGEPIELPPLS-DEEIVNLDIEITLNTANPKG 119
Query: 323 TMFWSVEGNRTIIFPGMSRDKYHATAVFDGVTVL 356
+F + N + +H + D TVL
Sbjct: 120 IIFETKRINSGDLLATPYDTIHHEAKITDYGTVL 153
>AF040648-6|AAO91708.1| 908|Caenorhabditis elegans Lethal protein
805, isoform d protein.
Length = 908
Score = 31.1 bits (67), Expect = 5.0
Identities = 21/93 (22%), Positives = 41/93 (44%), Gaps = 4/93 (4%)
Query: 733 GPPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQA 792
G P NI ++ ++ L+W P + I GY +V A++S + A
Sbjct: 438 GVPTNIRSADVDGQSIKLEWDVPRCDETHTPIDGYEYIV----YEASQSAPVDGASYVGA 493
Query: 793 TSLIMTNLTSGVSYSVQIAAETIIGLGPFSQKV 825
+I+ L V Y+ ++ + ++ G +S+ V
Sbjct: 494 PHVIIKGLKQNVDYTFKVRSRSVNGHSQWSKDV 526
>Z72518-2|CAA96700.1| 613|Caenorhabditis elegans Hypothetical
protein ZC374.2 protein.
Length = 613
Score = 30.7 bits (66), Expect = 6.6
Identities = 24/81 (29%), Positives = 36/81 (44%), Gaps = 4/81 (4%)
Query: 734 PPINIEMFILNTTTVHLKWSPPELQLQNGIITGYNVVVNWLDVPANKSMVAINTTVHQAT 793
PP++ I+N TTV LKW P Q+ Y V V L ++ S + AT
Sbjct: 192 PPLHFTANIMNPTTVQLKWQPAMPGKQH---IYYLVNVKQL-TTSSGSTLQNQQIKTAAT 247
Query: 794 SLIMTNLTSGVSYSVQIAAET 814
S + + +G Y + I + T
Sbjct: 248 SFTLGKMIAGEKYEMTIRSAT 268
>U41276-3|AAA82470.2| 517|Caenorhabditis elegans Hypothetical
protein C52B11.3 protein.
Length = 517
Score = 30.7 bits (66), Expect = 6.6
Identities = 22/71 (30%), Positives = 32/71 (45%), Gaps = 4/71 (5%)
Query: 927 KNTVTKTESLLWMENQPGVCL---SGNQTSQSKEKTNFEYDKVTHQLPEYAEVTSAR-AN 982
K + T+TES+L EN+P + + G Q+S S + F + T L + S
Sbjct: 253 KKSNTETESILSSENEPTLRIHFGRGKQSSSSLRNSRFHARESTRLLLKQVSCKSLNDRG 312
Query: 983 EWNTNKTATSP 993
E N N T P
Sbjct: 313 EHNNNNTVRQP 323
>U41272-8|AAA82451.2| 243|Caenorhabditis elegans 2 (zwei) ig-domain
protein protein6 protein.
Length = 243
Score = 30.7 bits (66), Expect = 6.6
Identities = 32/122 (26%), Positives = 55/122 (45%), Gaps = 8/122 (6%)
Query: 79 DAGVYWCEATNSYGTARSRNATLHVAVLRE-EFR-LEPESKQSAQGDTVVLECLPPRGSP 136
D+GVY+C+A G+ N + V V + FR + Q +V + C
Sbjct: 96 DSGVYYCQA--QVGSKVYMN-KMDVIVFEDIVFRDKQLHFGQVLATASVNISCEVSAKKD 152
Query: 137 EPNVYWKKNGQTLLFDGDSRMHLVDGGNLVIQDAR-QTDAGRYQC-IARNAAGTRESAIA 194
YW ++G+ +L +G G L IQ+ + + DAG+Y C + ++G+ +
Sbjct: 153 SVITYWTRHGKQIL-EGGKHKFYSRGSILEIQNYQPEQDAGQYTCEVFHVSSGSSNTKTV 211
Query: 195 TL 196
TL
Sbjct: 212 TL 213
>U28993-6|AAK31498.2| 639|Caenorhabditis elegans Hypothetical
protein F22D3.6 protein.
Length = 639
Score = 30.7 bits (66), Expect = 6.6
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYL-ITGPEDVVAQT--GSSVTFQCRVGGDPLPDV 233
R Q ++R +S L+ KP I PE V + ++ +C+ G P P++
Sbjct: 75 RLQFLSRTYEDEFDSIQFHLRRKFKPLRWIPDPEQQVTKEIDEGNIKLECKAQGFPCPEI 134
Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
W + +GRV + LR ++E +Y C A+N + S Y +Y
Sbjct: 135 KWFTKGSKEPVHIGRVYTI----LRCK---CSNEHQYKCVAKNEIR--EGSPYSEIY 182
>AF316599-1|AAG38591.1| 639|Caenorhabditis elegans paracaspase
protein.
Length = 639
Score = 30.7 bits (66), Expect = 6.6
Identities = 29/117 (24%), Positives = 49/117 (41%), Gaps = 12/117 (10%)
Query: 177 RYQCIARNAAGTRESAIATLKIHIKPYL-ITGPEDVVAQT--GSSVTFQCRVGGDPLPDV 233
R Q ++R +S L+ KP I PE V + ++ +C+ G P P++
Sbjct: 75 RLQFLSRTYEDEFDSIQFHLRRKFKPLRWIPDPEQQVTKEIDEGNIKLECKAQGFPCPEI 134
Query: 234 LWRRSAGGGNMPLGRVKVLDDGSLRLDNVILADEGEYSCEAENSVGAVSASGYLTVY 290
W + +GRV + LR ++E +Y C A+N + S Y +Y
Sbjct: 135 KWFTKGSKEPVHIGRVYTI----LRCK---CSNEHQYKCVAKNEIR--EGSPYSEIY 182
>AC024759-7|AAP13762.1| 483|Caenorhabditis elegans Hypothetical
protein Y37E11AR.7 protein.
Length = 483
Score = 30.7 bits (66), Expect = 6.6
Identities = 14/34 (41%), Positives = 22/34 (64%), Gaps = 2/34 (5%)
Query: 452 LVLKDLDKSDSGTYTCVASSRHGKYVWSGALLVD 485
LVLKD+D + +G Y C+ +RHG+ V S ++
Sbjct: 165 LVLKDVDANSTGHYRCI--NRHGRNVISNMYFLE 196
>Z77656-3|CAB01140.1| 424|Caenorhabditis elegans Hypothetical
protein F07B10.1 protein.
Length = 424
Score = 30.3 bits (65), Expect = 8.7
Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 7/73 (9%)
Query: 855 FVMETWFYFLIGAIVLFKIIVIAGII----YVRKYNIFAKKSALPNI--YDSNGTSLVTQ 908
F E ++F I++F +IV G++ YV YN KK P++ Y + S+
Sbjct: 341 FFFEAVYWFTPTIIIIFVLIVFEGLLGGSAYVNTYNKIHKK-VNPDVREYSLSAASMGNS 399
Query: 909 MNIKAAVSLSHPL 921
+ A LS PL
Sbjct: 400 LGTNIAAFLSIPL 412
>AL110479-24|CAJ76966.1| 1084|Caenorhabditis elegans Hypothetical
protein Y105C5B.21b protein.
Length = 1084
Score = 30.3 bits (65), Expect = 8.7
Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 13/124 (10%)
Query: 492 IHFFRAADVSSLPGPPT---KPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548
IH + S+L P P V +T+ W ++GY VE
Sbjct: 343 IHLRPTCNTSALRPAPNILEAPEFLEVDGDKITICWLPAQS--QLPVMGYDVEF------ 394
Query: 549 SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVG 608
+ ++ R + V + V V LI Y F V N+ G S PSP SD V +
Sbjct: 395 --RDLQQDDRWYKVNDQPVFACKMTVGDLIMDHDYQFRVLAHNASGCSQPSPPSDFVHIE 452
Query: 609 DDSN 612
+N
Sbjct: 453 PSTN 456
>AL110479-23|CAB60320.2| 1254|Caenorhabditis elegans Hypothetical
protein Y105C5B.21a protein.
Length = 1254
Score = 30.3 bits (65), Expect = 8.7
Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 13/124 (10%)
Query: 492 IHFFRAADVSSLPGPPT---KPITHNVTDTSVTLSWSQNNKIGSSSILGYQVEVFSRETL 548
IH + S+L P P V +T+ W ++GY VE
Sbjct: 513 IHLRPTCNTSALRPAPNILEAPEFLEVDGDKITICWLPAQS--QLPVMGYDVEF------ 564
Query: 549 SGNNTPRNSRGWVVIARRVHQTHYVVKSLIPGITYMFIVRTENSHGLSGPSPVSDSVTVG 608
+ ++ R + V + V V LI Y F V N+ G S PSP SD V +
Sbjct: 565 --RDLQQDDRWYKVNDQPVFACKMTVGDLIMDHDYQFRVLAHNASGCSQPSPPSDFVHIE 622
Query: 609 DDSN 612
+N
Sbjct: 623 PSTN 626
>AF326788-1|AAK38269.1| 424|Caenorhabditis elegans CLN-3.1 protein.
Length = 424
Score = 30.3 bits (65), Expect = 8.7
Identities = 22/73 (30%), Positives = 34/73 (46%), Gaps = 7/73 (9%)
Query: 855 FVMETWFYFLIGAIVLFKIIVIAGII----YVRKYNIFAKKSALPNI--YDSNGTSLVTQ 908
F E ++F I++F +IV G++ YV YN KK P++ Y + S+
Sbjct: 341 FFFEAVYWFTPTIIIIFVLIVFEGLLGGSAYVNTYNKIHKK-VNPDVREYSLSAASMGNS 399
Query: 909 MNIKAAVSLSHPL 921
+ A LS PL
Sbjct: 400 LGTNIAAFLSIPL 412
>AC024791-35|AAF60675.2| 462|Caenorhabditis elegans Innexin protein
22 protein.
Length = 462
Score = 30.3 bits (65), Expect = 8.7
Identities = 11/41 (26%), Positives = 22/41 (53%)
Query: 855 FVMETWFYFLIGAIVLFKIIVIAGIIYVRKYNIFAKKSALP 895
F+ W+Y L + ++ + ++++ KY +A KS LP
Sbjct: 282 FLFLYWWYILAMLVSIYSAVQFTAMLFLPKYQRYATKSLLP 322
Database: celegans
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 12,573,161
Number of sequences in database: 27,539
Lambda K H
0.315 0.132 0.393
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 31,876,518
Number of Sequences: 27539
Number of extensions: 1486249
Number of successful extensions: 10680
Number of sequences better than 10.0: 184
Number of HSP's better than 10.0 without gapping: 126
Number of HSP's successfully gapped in prelim test: 58
Number of HSP's that attempted gapping in prelim test: 3734
Number of HSP's gapped (non-prelim): 3288
length of query: 1207
length of database: 12,573,161
effective HSP length: 90
effective length of query: 1117
effective length of database: 10,094,651
effective search space: 11275725167
effective search space used: 11275725167
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 65 (30.3 bits)
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