Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000879-TA|BGIBMGA000879-PA|IPR008015|GMP
phosphodiesterase, delta subunit
(131 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_O43924 Cluster: Retinal rod rhodopsin-sensitive cGMP 3'... 233 8e-61
UniRef50_UPI00006CF342 Cluster: GMP-PDE, delta subunit family pr... 120 9e-27
UniRef50_A2FVK6 Cluster: GMP-PDE, delta subunit family protein; ... 111 4e-24
UniRef50_Q3SE82 Cluster: PDEdelta, putative; n=1; Paramecium tet... 84 7e-16
UniRef50_Q3SE85 Cluster: UNC119 homologue, putative; n=2; Parame... 40 0.012
UniRef50_A4I307 Cluster: Putative uncharacterized protein; n=6; ... 40 0.012
UniRef50_Q3SE90 Cluster: UNC119 homologue, putative; n=10; Oligo... 39 0.028
UniRef50_Q5SYM3 Cluster: Unc-119 homolog; n=2; Eutheria|Rep: Unc... 39 0.036
UniRef50_Q4T421 Cluster: Chromosome undetermined SCAF9846, whole... 38 0.048
UniRef50_Q13432 Cluster: Protein unc-119 homolog; n=54; Eumetazo... 38 0.084
UniRef50_Q9XYQ2 Cluster: Protein unc-119 homolog; n=22; Eukaryot... 36 0.26
UniRef50_A5USR7 Cluster: DNA-directed RNA polymerase; n=5; Chlor... 35 0.59
UniRef50_A4BE95 Cluster: Peptidase M23B; n=1; Reinekea sp. MED29... 35 0.59
UniRef50_Q7QVI4 Cluster: GLP_21_34647_35153; n=1; Giardia lambli... 34 1.0
UniRef50_UPI00006CBA24 Cluster: hypothetical protein TTHERM_0055... 33 1.8
UniRef50_UPI0000545996 Cluster: PREDICTED: similar to ENSANGP000... 33 2.4
UniRef50_A4BAS2 Cluster: Putative RTX toxin; n=1; Reinekea sp. M... 32 3.2
UniRef50_UPI00015C5915 Cluster: hypothetical protein CKO_02092; ... 32 4.2
UniRef50_A3EZV6 Cluster: Putative DNA-binding protein; n=1; Salm... 32 4.2
UniRef50_Q4SHF6 Cluster: Chromosome 5 SCAF14581, whole genome sh... 31 5.5
UniRef50_Q45962 Cluster: RepB; n=2; Clostridium|Rep: RepB - Clos... 31 7.3
>UniRef50_O43924 Cluster: Retinal rod rhodopsin-sensitive cGMP
3',5'-cyclic phosphodiesterase subunit delta; n=31;
Eumetazoa|Rep: Retinal rod rhodopsin-sensitive cGMP
3',5'-cyclic phosphodiesterase subunit delta - Homo
sapiens (Human)
Length = 150
Score = 233 bits (570), Expect = 8e-61
Identities = 103/131 (78%), Positives = 120/131 (91%)
Query: 1 MNLRDADTGKILWQHNEDMSSPDAEHEARVPKRILKCRVVSREMNFSSIESMDRFRLEQK 60
MNLRDA+TGKILWQ ED+S P EHEARVPK+ILKC+ VSRE+NFSS E M++FRLEQK
Sbjct: 20 MNLRDAETGKILWQGTEDLSVPGVEHEARVPKKILKCKAVSRELNFSSTEQMEKFRLEQK 79
Query: 61 VLFKGRCLEEWFFDFGYVIPNSTNTWQSVIESAPESQMMPANVLNGNVVIETKFFDGDLL 120
V FKG+CLEEWFF+FG+VIPNSTNTWQS+IE+APESQMMPA+VL GNV+IETKFFD DLL
Sbjct: 80 VYFKGQCLEEWFFEFGFVIPNSTNTWQSLIEAAPESQMMPASVLTGNVIIETKFFDDDLL 139
Query: 121 ITTSRVRLFYI 131
++TSRVRLFY+
Sbjct: 140 VSTSRVRLFYV 150
>UniRef50_UPI00006CF342 Cluster: GMP-PDE, delta subunit family
protein; n=1; Tetrahymena thermophila SB210|Rep:
GMP-PDE, delta subunit family protein - Tetrahymena
thermophila SB210
Length = 333
Score = 120 bits (289), Expect = 9e-27
Identities = 55/123 (44%), Positives = 87/123 (70%), Gaps = 4/123 (3%)
Query: 1 MNLRDADTGKILW--QHNEDMSSPDAEHEARVPKRILKCRVVSREMNFSSIESMDRFRLE 58
+ + DADTG LW Q ++ + + + E +A +PK IL+C+ VSR++NFSS ++ + L+
Sbjct: 167 LTMGDADTGNKLWVCQDSQQLINSEKEIQANIPKEILQCKSVSRDINFSSAHTIKKLSLK 226
Query: 59 QKVLFKGRCLEEWFFDFGYVIPNSTNTWQSVIESAPESQMMPANVLNGNVVIETKFFDGD 118
Q G+ +E++ FDFG+VIP STN WQS+I+++ E M+P +L+GN+V+ETKF+D D
Sbjct: 227 QIFSLNGQPIEQFSFDFGFVIPGSTNNWQSIIQASEE--MIPVEILSGNLVVETKFYDED 284
Query: 119 LLI 121
LI
Sbjct: 285 NLI 287
>UniRef50_A2FVK6 Cluster: GMP-PDE, delta subunit family protein;
n=1; Trichomonas vaginalis G3|Rep: GMP-PDE, delta
subunit family protein - Trichomonas vaginalis G3
Length = 156
Score = 111 bits (267), Expect = 4e-24
Identities = 50/131 (38%), Positives = 84/131 (64%), Gaps = 1/131 (0%)
Query: 1 MNLRDADTGKILWQHNEDMSSP-DAEHEARVPKRILKCRVVSREMNFSSIESMDRFRLEQ 59
+ L+++ GK+ W + A +A +PK +L V RE+ FS+ E++ FR++Q
Sbjct: 25 LTLKNSSNGKVAWTSKDWTDDVFSAVKDAHLPKEMLGYPAVGREIVFSTEEAIKEFRIQQ 84
Query: 60 KVLFKGRCLEEWFFDFGYVIPNSTNTWQSVIESAPESQMMPANVLNGNVVIETKFFDGDL 119
+L G+ +E+W + FG+VIP S N+W++++E+A E M+PA L+GN+ I T F+ G+L
Sbjct: 85 DILVHGQNIEQWNYKFGFVIPGSENSWETIVEAAGEGNMLPAEYLSGNMYILTSFYAGNL 144
Query: 120 LITTSRVRLFY 130
I+ S VR+FY
Sbjct: 145 FISRSVVRVFY 155
>UniRef50_Q3SE82 Cluster: PDEdelta, putative; n=1; Paramecium
tetraurelia|Rep: PDEdelta, putative - Paramecium
tetraurelia
Length = 154
Score = 84.2 bits (199), Expect = 7e-16
Identities = 38/128 (29%), Positives = 70/128 (54%), Gaps = 1/128 (0%)
Query: 3 LRDADTGKILWQHNEDMSSPDAEHEARVPKRILKCRVVSREMNFSSIESMDRFRLEQKVL 62
++D++T ++ W + + D PK I+ + +R + FS+ E + L Q
Sbjct: 27 MKDSETQQVYWDSTSENITQDIMDITLDPK-IITSKAATRSIQFSTKEKLQDLILIQDAY 85
Query: 63 FKGRCLEEWFFDFGYVIPNSTNTWQSVIESAPESQMMPANVLNGNVVIETKFFDGDLLIT 122
+ +E + F FG+V+P + NTW S I + P QM+P + +GN++++ + F+ D LI
Sbjct: 86 LHDQKIEHFVFKFGFVMPETVNTWDSTIVNRPPEQMLPKEIQSGNLIVDIQMFEQDHLIF 145
Query: 123 TSRVRLFY 130
+VR+FY
Sbjct: 146 NVKVRIFY 153
>UniRef50_Q3SE85 Cluster: UNC119 homologue, putative; n=2;
Paramecium tetraurelia|Rep: UNC119 homologue, putative -
Paramecium tetraurelia
Length = 174
Score = 40.3 bits (90), Expect = 0.012
Identities = 24/91 (26%), Positives = 43/91 (47%), Gaps = 2/91 (2%)
Query: 3 LRDADTGKILWQHNEDMSSPDAEHEA-RVPKRILKCRVVSREMNFSSIES-MDRFRLEQK 60
LRDAD IL+ D + E + + + + + F + + + L +
Sbjct: 35 LRDADDNFILFDFENDEENQQQEVLSYQFTPQYFDIKTLGATKIFKTFDKPLKNLLLVDR 94
Query: 61 VLFKGRCLEEWFFDFGYVIPNSTNTWQSVIE 91
FK ++E+ F F + IP+STNTW+S+ +
Sbjct: 95 FYFKNNLIKEYEFCFPFCIPHSTNTWESMYD 125
>UniRef50_A4I307 Cluster: Putative uncharacterized protein; n=6;
Trypanosomatidae|Rep: Putative uncharacterized protein -
Leishmania infantum
Length = 197
Score = 40.3 bits (90), Expect = 0.012
Identities = 13/42 (30%), Positives = 30/42 (71%)
Query: 50 ESMDRFRLEQKVLFKGRCLEEWFFDFGYVIPNSTNTWQSVIE 91
+ + +FR+ ++ F+ ++ + F+FG+ IP+STNTW+++ +
Sbjct: 110 QPVPKFRMIERHYFRNVLIKSFDFEFGFCIPHSTNTWEAIYD 151
>UniRef50_Q3SE90 Cluster: UNC119 homologue, putative; n=10;
Oligohymenophorea|Rep: UNC119 homologue, putative -
Paramecium tetraurelia
Length = 187
Score = 39.1 bits (87), Expect = 0.028
Identities = 34/146 (23%), Positives = 68/146 (46%), Gaps = 21/146 (14%)
Query: 3 LRDADTGKILWQHNEDMSS-------PDAEHEARVPK-----RILKCRVVSREMNFS-SI 49
+RD ++G++L++ D P + ++R K + + + + ++ FS
Sbjct: 40 IRDMESGQVLFEVERDPDEESIENLPPALQDDSRRIKYHFGPQFFELKTIGAQLTFSVGD 99
Query: 50 ESMDRFRLEQKVLFKGRCLEEWFFDFGYVIPNSTNTWQSVIESAPE-----SQMMPANVL 104
+ + F + ++ F+ L + F F + IPNSTNTW+ I + PE Q+M N
Sbjct: 100 KPIKNFTIIERHYFRNVLLRSYEFQFPFCIPNSTNTWEH-IYTIPEIAEDIKQLMIENPF 158
Query: 105 NGNVVIETKFFDGDLLITTSRVRLFY 130
+ ++ +F GD L+ ++ Y
Sbjct: 159 --DTKSDSFYFVGDTLVMHNKAEYDY 182
>UniRef50_Q5SYM3 Cluster: Unc-119 homolog; n=2; Eutheria|Rep:
Unc-119 homolog - Mus musculus (Mouse)
Length = 262
Score = 38.7 bits (86), Expect = 0.036
Identities = 20/73 (27%), Positives = 40/73 (54%), Gaps = 1/73 (1%)
Query: 35 LKCRVVSREMNFS-SIESMDRFRLEQKVLFKGRCLEEWFFDFGYVIPNSTNTWQSVIESA 93
L+ R V + F+ + ++ FR+ ++ F+ + L+ + F FG+ IP+S NT + + +
Sbjct: 138 LRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFP 197
Query: 94 PESQMMPANVLNG 106
P S+ + L G
Sbjct: 198 PLSEELILKSLQG 210
>UniRef50_Q4T421 Cluster: Chromosome undetermined SCAF9846, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF9846,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 210
Score = 38.3 bits (85), Expect = 0.048
Identities = 15/40 (37%), Positives = 26/40 (65%)
Query: 52 MDRFRLEQKVLFKGRCLEEWFFDFGYVIPNSTNTWQSVIE 91
++ FR+ ++ F+ L+ + FDFG+ IPNS NT + + E
Sbjct: 126 LNHFRMIERHYFRDHLLKSFDFDFGFCIPNSRNTCEHIYE 165
>UniRef50_Q13432 Cluster: Protein unc-119 homolog; n=54;
Eumetazoa|Rep: Protein unc-119 homolog - Homo sapiens
(Human)
Length = 240
Score = 37.5 bits (83), Expect = 0.084
Identities = 18/71 (25%), Positives = 41/71 (57%), Gaps = 1/71 (1%)
Query: 35 LKCRVVSREMNFS-SIESMDRFRLEQKVLFKGRCLEEWFFDFGYVIPNSTNTWQSVIESA 93
L+ R V + F+ + ++ FR+ ++ F+ + L+ + F FG+ IP+S NT + + +
Sbjct: 138 LRLRQVGATVEFTVGDKPVNNFRMIERHYFRNQLLKSFDFHFGFCIPSSKNTCEHIYDFP 197
Query: 94 PESQMMPANVL 104
P S+ + + ++
Sbjct: 198 PLSEELISEMI 208
>UniRef50_Q9XYQ2 Cluster: Protein unc-119 homolog; n=22;
Eukaryota|Rep: Protein unc-119 homolog - Drosophila
melanogaster (Fruit fly)
Length = 265
Score = 35.9 bits (79), Expect = 0.26
Identities = 20/78 (25%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 17 EDMSSPDAEHEARVP--KRILKCRVVSREMNFS-SIESMDRFRLEQKVLFKGRCLEEWFF 73
+D + P+A R L + V + F+ + ++ FR+ ++ F+ R L+ + F
Sbjct: 141 DDTADPNAGRYVRYQFTPAFLNLKTVGATVEFTVGSQPLNNFRMIERHFFRDRLLKTFDF 200
Query: 74 DFGYVIPNSTNTWQSVIE 91
+FG+ P S NT + + E
Sbjct: 201 EFGFCFPFSKNTVEHIYE 218
>UniRef50_A5USR7 Cluster: DNA-directed RNA polymerase; n=5;
Chloroflexi (class)|Rep: DNA-directed RNA polymerase -
Roseiflexus sp. RS-1
Length = 1229
Score = 34.7 bits (76), Expect = 0.59
Identities = 18/56 (32%), Positives = 33/56 (58%), Gaps = 1/56 (1%)
Query: 5 DADTGKILWQHNEDMSSPDAEHEARVPKRILKCR-VVSREMNFSSIESMDRFRLEQ 59
D TG+++ ++++ AE P +I+K R VVS+E+++ S + DRF + Q
Sbjct: 580 DPTTGEVIAHAGQEVNRALAERIVETPLKIIKIRPVVSQEVDYLSADEEDRFVIVQ 635
>UniRef50_A4BE95 Cluster: Peptidase M23B; n=1; Reinekea sp.
MED297|Rep: Peptidase M23B - Reinekea sp. MED297
Length = 374
Score = 34.7 bits (76), Expect = 0.59
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 9/110 (8%)
Query: 14 QHNEDMSSPDAEHEARVPKRI--LKCRVVSREMNFSSIESMDRFRLEQKVLFKGRCLEEW 71
Q +++++ +E E RV + I L+ ++ SR++NF+ E ++ R GR +
Sbjct: 205 QTDDEIARMVSERE-RVTELITELEAQLASRDLNFAGAEPVEEARGSLPWPVDGRLMNR- 262
Query: 72 FFDFGYVIPNSTNTWQSVIESAPESQMMPANVLNGNVVIETKFFDGDLLI 121
+G I S TWQ + +A E + P ++G +I FF + L+
Sbjct: 263 ---YGRAINQSGLTWQGWLLAADEGE--PVRAVHGGRIIFADFFKSNGLL 307
>UniRef50_Q7QVI4 Cluster: GLP_21_34647_35153; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_21_34647_35153 - Giardia lamblia
ATCC 50803
Length = 168
Score = 33.9 bits (74), Expect = 1.0
Identities = 18/80 (22%), Positives = 38/80 (47%), Gaps = 1/80 (1%)
Query: 50 ESMDRFRLEQKVLFKGRCLEEWFFDFGYVIPNSTNTWQSVIE-SAPESQMMPANVLNGNV 108
E + ++ ++ + +G L+ + FD ++ P + NTW+++ E L G
Sbjct: 86 EPISGIKIVEEHILQGVPLQRYDFDLMFLAPRTQNTWETLYEPEFKRGHNFEEQALAGPW 145
Query: 109 VIETKFFDGDLLITTSRVRL 128
+I T + D L+ +R +L
Sbjct: 146 IIITSLYISDKLMLRNRAQL 165
>UniRef50_UPI00006CBA24 Cluster: hypothetical protein
TTHERM_00558430; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00558430 - Tetrahymena
thermophila SB210
Length = 1322
Score = 33.1 bits (72), Expect = 1.8
Identities = 17/77 (22%), Positives = 36/77 (46%)
Query: 10 KILWQHNEDMSSPDAEHEARVPKRILKCRVVSREMNFSSIESMDRFRLEQKVLFKGRCLE 69
K ++++ +D + + + K+++KC+V +N+S L K L ++
Sbjct: 683 KFVYENKDDKELDELDKTQMIFKKLIKCQVEKAAINYSKSRDEYIKILSNKYLKNNFLID 742
Query: 70 EWFFDFGYVIPNSTNTW 86
+FDF N+ NT+
Sbjct: 743 LKYFDFSNSSNNNLNTY 759
>UniRef50_UPI0000545996 Cluster: PREDICTED: similar to
ENSANGP00000004777 isoform 2; n=3; Danio rerio|Rep:
PREDICTED: similar to ENSANGP00000004777 isoform 2 -
Danio rerio
Length = 261
Score = 32.7 bits (71), Expect = 2.4
Identities = 13/40 (32%), Positives = 27/40 (67%)
Query: 50 ESMDRFRLEQKVLFKGRCLEEWFFDFGYVIPNSTNTWQSV 89
+++++FRL +K F+ L+ + F+ G+ IP+S NT + +
Sbjct: 168 KAVNKFRLIEKHYFRDLLLKTFDFEIGFCIPHSRNTCEHI 207
>UniRef50_A4BAS2 Cluster: Putative RTX toxin; n=1; Reinekea sp.
MED297|Rep: Putative RTX toxin - Reinekea sp. MED297
Length = 1629
Score = 32.3 bits (70), Expect = 3.2
Identities = 13/28 (46%), Positives = 17/28 (60%)
Query: 96 SQMMPANVLNGNVVIETKFFDGDLLITT 123
S +MPA NG + + + FDGDLL T
Sbjct: 885 STLMPAQNFNGELTVPVRIFDGDLLSNT 912
>UniRef50_UPI00015C5915 Cluster: hypothetical protein CKO_02092;
n=1; Citrobacter koseri ATCC BAA-895|Rep: hypothetical
protein CKO_02092 - Citrobacter koseri ATCC BAA-895
Length = 83
Score = 31.9 bits (69), Expect = 4.2
Identities = 15/50 (30%), Positives = 28/50 (56%), Gaps = 3/50 (6%)
Query: 35 LKCRVVSREMNFS-SIESMDRFRLEQKVLFKG--RCLEEWFFDFGYVIPN 81
+KC V+++ +N + +++F + V+F G C E+F+D GY N
Sbjct: 1 MKCGVINQTLNLCLACADINKFHIHYLVIFAGIFGCQHEYFYDSGYSSAN 50
>UniRef50_A3EZV6 Cluster: Putative DNA-binding protein; n=1;
Salmonella phage SETP3|Rep: Putative DNA-binding protein
- Salmonella phage SETP3
Length = 223
Score = 31.9 bits (69), Expect = 4.2
Identities = 14/49 (28%), Positives = 25/49 (51%)
Query: 50 ESMDRFRLEQKVLFKGRCLEEWFFDFGYVIPNSTNTWQSVIESAPESQM 98
+ +++F + + + +GR ++WF D GY I T T S E +M
Sbjct: 163 KQLEQFGVYNRSVKRGRVFQQWFIDKGYGIMRETETGHSQAMFFAEGEM 211
>UniRef50_Q4SHF6 Cluster: Chromosome 5 SCAF14581, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 5 SCAF14581, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1795
Score = 31.5 bits (68), Expect = 5.5
Identities = 18/59 (30%), Positives = 32/59 (54%)
Query: 3 LRDADTGKILWQHNEDMSSPDAEHEARVPKRILKCRVVSREMNFSSIESMDRFRLEQKV 61
L D D+ K++ N ++ P E EA K+ LK + S MN I ++++F+ Q++
Sbjct: 411 LVDLDSSKVIAPTNAEILPPLPEPEAMELKKHLKQALASMSMNTQPILNLEKFQEGQEL 469
>UniRef50_Q45962 Cluster: RepB; n=2; Clostridium|Rep: RepB -
Clostridium butyricum
Length = 362
Score = 31.1 bits (67), Expect = 7.3
Identities = 17/51 (33%), Positives = 28/51 (54%)
Query: 19 MSSPDAEHEARVPKRILKCRVVSREMNFSSIESMDRFRLEQKVLFKGRCLE 69
MS D+ +A + K +LK + + E N + I+ +RF E ++FK LE
Sbjct: 1 MSLKDSLKKAEIDKDLLKDIINNIEYNKTIIKYYERFSKESSIVFKNTILE 51
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.322 0.135 0.410
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 147,052,189
Number of Sequences: 1657284
Number of extensions: 5291165
Number of successful extensions: 11305
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 11285
Number of HSP's gapped (non-prelim): 22
length of query: 131
length of database: 575,637,011
effective HSP length: 92
effective length of query: 39
effective length of database: 423,166,883
effective search space: 16503508437
effective search space used: 16503508437
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 66 (30.7 bits)
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