SilkBase IMG001 IMG002 IMG003 IMG005 IMG006 IMG007 IMG008 IMG009 kuwako IMG010 IMG011 IMG012

Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000875-TA|BGIBMGA000875-PA|IPR002018|Carboxylesterase,
type B
         (531 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

BC042510-1|AAH42510.1|  722|Homo sapiens CEL protein protein.         163   1e-39
S79774-1|AAB35488.2|  742|Homo sapiens bile salt-dependent lipas...   160   1e-38
X54457-1|CAA38325.1|  745|Homo sapiens protein ( Human mRNA for ...   159   2e-38
M94579-1|AAA51973.1|  745|Homo sapiens carboxyl ester lipase pro...   159   2e-38
M85201-1|AAA52014.1|  747|Homo sapiens cholesterol esterase prot...   159   2e-38
M54994-1|AAA63211.1|  742|Homo sapiens bile salt-activated lipas...   159   2e-38
AL162417-8|CAI13412.1|  756|Homo sapiens carboxyl ester lipase (...   159   2e-38
AF081673-1|AAC71012.1|  612|Homo sapiens bile salt-dependent lip...   159   2e-38
AF072711-1|AAC26514.1|  745|Homo sapiens carboxyl ester lipase p...   159   2e-38
M55040-1|AAA68151.1|  614|Homo sapiens acetylcholinesterase prot...   157   1e-37
BC105062-1|AAI05063.1|  617|Homo sapiens acetylcholinesterase, i...   157   1e-37
BC105060-1|AAI05061.1|  617|Homo sapiens acetylcholinesterase (Y...   157   1e-37
AY750146-1|AAU43801.1|  617|Homo sapiens acetylcholinesterase (Y...   157   1e-37
AK223443-1|BAD97163.1|  614|Homo sapiens acetylcholinesterase is...   157   1e-37
AC011895-2|AAP22364.1|  617|Homo sapiens unknown protein.             157   1e-37
AC011895-1|AAP22365.1|  614|Homo sapiens unknown protein.             157   1e-37
BC094752-1|AAH94752.1|  640|Homo sapiens ACHE protein protein.        156   2e-37
AY268104-1|AAP20868.1|  567|Homo sapiens cholesteryl ester hydro...   154   6e-37
M65261-1|AAA83932.1|  454|Homo sapiens carboxylesterase protein.      153   2e-36
BC117126-1|AAI17127.1|  575|Homo sapiens CES7 protein protein.        152   3e-36
BC069501-1|AAH69501.1|  575|Homo sapiens CES7 protein protein.        152   3e-36
AY907669-1|AAX86044.1|  575|Homo sapiens carboxylesterase 5 prot...   152   3e-36
X52973-1|CAA37147.1|  503|Homo sapiens monocyte/macrophage serin...   152   3e-36
L07765-1|AAA35711.1|  566|Homo sapiens carboxylesterase protein.      152   3e-36
L07764-1|AAA16036.1|  568|Homo sapiens carboxylesterase protein.      152   3e-36
S73751-1|AAC60631.2|  568|Homo sapiens acyl coenzyme A:cholester...   151   5e-36
M73499-1|AAA35649.1|  567|Homo sapiens carboxylesterase protein.      151   5e-36
M55509-1|AAA35650.1|  507|Homo sapiens carboxylesterase protein.      151   5e-36
D21088-1|BAA04650.1|  567|Homo sapiens carboxylesterase protein.      151   5e-36
BC110338-1|AAI10339.1|  567|Homo sapiens carboxylesterase 1 (mon...   151   5e-36
BC012418-1|AAH12418.1|  566|Homo sapiens carboxylesterase 1 (mon...   151   5e-36
AF177775-1|AAD53175.1|  567|Homo sapiens egasyn protein.              151   5e-36
AB119998-1|BAC87751.1|  567|Homo sapiens carboxylesterase HU1b p...   151   5e-36
AB119997-1|BAC87750.1|  567|Homo sapiens carboxylesterase HU1a p...   151   5e-36
AB119996-1|BAC87749.1|  567|Homo sapiens carboxylesterase HU1b p...   151   5e-36
AB119995-1|BAC87748.1|  567|Homo sapiens carboxylesterase HU1a p...   151   5e-36
BC036813-1|AAH36813.1|  546|Homo sapiens ACHE protein protein.        151   6e-36
AK090997-1|BAC03565.1|  469|Homo sapiens protein ( Homo sapiens ...   151   8e-36
AB025027-1|BAB85656.1|  565|Homo sapiens brain carboxylesterase ...   149   2e-35
M32391-1|AAA99296.1|  602|Homo sapiens butyrylcholinesterase pro...   147   1e-34
M16541-1|AAA98113.1|  602|Homo sapiens BCHE protein.                  147   1e-34
M16474-1|AAA52015.1|  602|Homo sapiens BCHE protein.                  147   1e-34
BC018141-1|AAH18141.1|  602|Homo sapiens butyrylcholinesterase p...   147   1e-34
BC064573-1|AAH64573.1|  442|Homo sapiens FLJ37464 protein protein.    146   2e-34
AB025028-1|BAA84996.1|  567|Homo sapiens brain carboxylesterase ...   142   4e-33
AB025026-1|BAA84995.1|  429|Homo sapiens brain carboxylesterase ...   140   1e-32
Y09616-1|CAA70831.1|  559|Homo sapiens carboxylesterase protein.      136   2e-31
U60553-1|AAB03611.1|  550|Homo sapiens carboxylesterase protein.      136   2e-31
D50579-1|BAA23606.1|  559|Homo sapiens carboxylesterase precurso...   136   2e-31
BC032095-1|AAH32095.1|  623|Homo sapiens carboxylesterase 2 (int...   136   2e-31
AY851164-1|AAW29943.1|  623|Homo sapiens carboxylesterase 2 (int...   136   2e-31
AK222724-1|BAD96444.1|  582|Homo sapiens carboxylesterase 2 isof...   136   2e-31
BC084555-1|AAH84555.1|  454|Homo sapiens FLJ37464 protein protein.    135   3e-31
AY358504-1|AAQ88868.1|  545|Homo sapiens carboxylesterase Hlo pr...   135   3e-31
BC053670-1|AAH53670.1|  568|Homo sapiens CES3 protein protein.        135   4e-31
BC028738-1|AAH28738.1|  518|Homo sapiens NLGN3 protein protein.       131   5e-30
AY358609-1|AAQ88972.1|  571|Homo sapiens carboxylesterase Hlo pr...   131   7e-30
BC069548-1|AAH69548.1|  525|Homo sapiens carboxylesterase 7 prot...   130   9e-30
AK056109-1|BAB71094.1|  525|Homo sapiens protein ( Homo sapiens ...   130   9e-30
AF106005-1|AAF14185.1|  288|Homo sapiens carboxylesterase-relate...   128   4e-29
BC098417-1|AAH98417.1|  587|Homo sapiens CES2 protein protein.        127   8e-29
BC071874-1|AAH71874.1|  586|Homo sapiens CES2 protein protein.        127   8e-29
BC032555-1|AAH32555.1|  823|Homo sapiens neuroligin 1 protein.        126   2e-28
AB028993-1|BAA83022.2|  826|Homo sapiens KIAA1070 protein protein.    126   2e-28
AF334270-1|AAO32948.1|  526|Homo sapiens apoptosis-related acety...   123   1e-27
BC034018-1|AAH34018.1|  816|Homo sapiens neuroligin 4, X-linked ...   123   2e-27
AF376803-1|AAM46112.1|  816|Homo sapiens neuroligin X protein.        123   2e-27
AF376802-1|AAM46111.1|  835|Homo sapiens neuroligin 2 protein.        123   2e-27
AB033086-1|BAA86574.1|  817|Homo sapiens KIAA1260 protein protein.    123   2e-27
BC113551-1|AAI13552.1|  816|Homo sapiens neuroligin 4, Y-linked ...   122   2e-27
BC113525-1|AAI13526.1|  816|Homo sapiens neuroligin 4, Y-linked ...   122   2e-27
AF376804-1|AAM46113.1|  816|Homo sapiens neuroligin Y protein.        122   2e-27
BX641059-1|CAE46030.1|  351|Homo sapiens hypothetical protein pr...   115   4e-25
BC051715-1|AAH51715.1|  828|Homo sapiens neuroligin 3 protein.        115   4e-25
AF217413-2|AAF71232.1|  828|Homo sapiens neuroligin 3 isoform pr...   115   4e-25
AF217413-1|AAF71233.1|  848|Homo sapiens neuroligin 3 isoform pr...   113   1e-24
AF217412-1|AAF71231.1|  558|Homo sapiens neuroligin 3 isoform HN...   113   1e-24
AB040913-1|BAA96004.1|  682|Homo sapiens KIAA1480 protein protein.    113   1e-24
AF217411-1|AAF71230.1|  828|Homo sapiens neuroligin 3 isoform HN...   113   1e-24
AY358562-1|AAQ88925.1|  816|Homo sapiens NLGN4 protein.               110   1e-23
AB023168-1|BAA76795.2|  679|Homo sapiens KIAA0951 protein protein.    110   1e-23
BC131699-1|AAI31700.1|  151|Homo sapiens CES4 protein protein.        105   5e-22
AK097538-1|BAC05093.1|  207|Homo sapiens protein ( Homo sapiens ...    97   1e-19
X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.          91   7e-18
U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.          91   7e-18
AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.        91   1e-17
AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor...    91   1e-17
BC127887-1|AAI27888.1|  422|Homo sapiens Unknown (protein for IM...    89   4e-17
AK094783-1|BAC04422.1|  367|Homo sapiens protein ( Homo sapiens ...    88   6e-17
L32179-1|AAA35551.1|  399|Homo sapiens arylacetamide deacetylase...    47   1e-04
BC032309-1|AAH32309.1|  399|Homo sapiens arylacetamide deacetyla...    47   1e-04
BC032567-1|AAH32567.1|  134|Homo sapiens NLGN4Y protein protein.       40   0.029
BC132824-1|AAI32825.1|  303|Homo sapiens AFMID protein protein.        36   0.27 
BC003170-1|AAH03170.1| 1087|Homo sapiens ubiquitin associated pr...    33   2.5  
AL590431-28|CAH71286.1|  382|Homo sapiens ubiquitin associated p...    33   2.5  
AL590431-27|CAH71285.1|  398|Homo sapiens ubiquitin associated p...    33   2.5  
AL590431-26|CAH71284.1| 1087|Homo sapiens ubiquitin associated p...    33   2.5  
AJ243670-1|CAB65101.2|  398|Homo sapiens NICE-4 protein protein.       33   2.5  
AJ243669-1|CAB65100.2|  408|Homo sapiens NICE-4 protein protein.       33   2.5  
AB037787-1|BAA92604.1|  550|Homo sapiens KIAA1366 protein protein.     32   5.8  
BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein.        31   7.7  
AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2 ...    31   7.7  

>BC042510-1|AAH42510.1|  722|Homo sapiens CEL protein protein.
          Length = 722

 Score =  163 bits (396), Expect = 1e-39
 Identities = 131/458 (28%), Positives = 214/458 (46%), Gaps = 40/458 (8%)

Query: 88  SSVGEQTLNCLRLNIYVPSAASS-RNPMPVLVWIHGGDFATGSA------SDY---GVKN 137
           S+ G++  +CL LNI+VP         +PV++WI+GG F  GS       ++Y   G + 
Sbjct: 96  STYGDE--DCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEI 153

Query: 138 IVRHGVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTI 197
             R  V+VVT NYR+GP GFL        GN GLRDQ+ A++W++ NIA+FGG+P N+T+
Sbjct: 154 ATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITL 213

Query: 198 AGQDAGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTE 256
            G+ AG  SV LQ  S  N+ L  + I +SG   S  +     +  A K+A  +G    +
Sbjct: 214 FGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGD 273

Query: 257 TEEAIQFLTKTSPDLVVAAAKE--LELQLKPCRERSFSGI--SNFVESDPYSLTNKKKVR 312
                Q L  T P  +  A K     L+        F  +   +F+ +DP +L       
Sbjct: 274 AARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLY--ANAA 331

Query: 313 NTPIMIGNTNKEKKSL-SADYFSTDPFYEKLKSNFN--LDEAQIEKAAKNVRH-FYIGDS 368
           +   + G  N +     S D  + +   +K+  +F   + E  I K  +  +  F +   
Sbjct: 332 DIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEDFYKLVSEFTITKGLRGAKTTFDVYTE 391

Query: 369 SLSAEVASE-----LQDFESDFVYNHPSQRTITQ-LLDENAGKIYEYLFSYSGELED--- 419
           S + + + E     + DFE+D ++  P++  + Q   +  + K Y YLFS+   +     
Sbjct: 392 SWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYPK 451

Query: 420 --GAEHSSELNYLFET--AGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIW 475
             GA+H+ ++ Y+F    A  +    +++ +   +   WTNF K G+P       +PT W
Sbjct: 452 WVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPN-MGDSAVPTHW 510

Query: 476 EPVTADTRPVLVLDKDVRLDSRIERQR---MAYWDLFF 510
           EP T +    L + K +   S     R   + YW L +
Sbjct: 511 EPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTY 548


>S79774-1|AAB35488.2|  742|Homo sapiens bile salt-dependent lipase
           protein.
          Length = 742

 Score =  160 bits (389), Expect = 1e-38
 Identities = 132/459 (28%), Positives = 214/459 (46%), Gaps = 41/459 (8%)

Query: 88  SSVGEQTLNCLRLNIYVPSAASS-RNPMPVLVWIHGGDFATGSA------SDY---GVKN 137
           S+ G++  +CL LNI+VP         +PV++WI+GG F  GS       ++Y   G + 
Sbjct: 93  STYGDE--DCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEI 150

Query: 138 IVRHGVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTI 197
             R  V+VVT NYR+GP GFL        GN GLRDQ+ A++W++ NIA+FGG+P N+T+
Sbjct: 151 ATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITL 210

Query: 198 AGQDAGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTE 256
            G+ AG  SV LQ  S  N+ L    I +SG   S  +     +  A K+A  +G    +
Sbjct: 211 FGESAGGASVSLQTLSPYNKGLIRAAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGD 270

Query: 257 TEEAIQFLTKTSPDLVVAAAKE--LELQLKPCRERSFSGI--SNFVESDPYSLTNKKKVR 312
                Q L  T P  V  A K     L+        F  +   +F+ +DP +L       
Sbjct: 271 AARMAQCLKVTDPAAVTVAYKVPLAGLEYPMLHYVGFVPVIDEDFIPADPINL--YANAA 328

Query: 313 NTPIMIGNTNKEKKSL-SADYFSTDPFYEKL-KSNFN--LDEAQIEKAAKNVR-HFYIGD 367
           +   + G  N +     S D  + +   +K+ + +F   + E  I K  +  +  F +  
Sbjct: 329 DIDYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGLRGAKTTFDVYT 388

Query: 368 SSLSAEVASE-----LQDFESDFVYNHPSQRTITQ-LLDENAGKIYEYLFSYSGELE--- 418
            S + + + E     + DFE+D ++  P++  + Q   +  + K Y YLFS+   +    
Sbjct: 389 ESWAQDPSQENKKKIVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYP 448

Query: 419 --DGAEHSSELNYLF--ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTI 474
              GA+H+ ++ Y+F    A  +    +++ +   +   WTNF K G+P       +PT 
Sbjct: 449 KWVGADHADDIQYVFGKPFATPTGYRPQDRTVFKAMIAYWTNFAKTGDPN-MGDSAVPTH 507

Query: 475 WEPVTADTRPVLVLDKDVRLDSRIERQR---MAYWDLFF 510
           WEP T +    L + K +   S     R   + YW L +
Sbjct: 508 WEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTY 546


>X54457-1|CAA38325.1|  745|Homo sapiens protein ( Human mRNA for
           bile-salt-stimulated lipase (BSSL) (EC 3.1.1.3). ).
          Length = 745

 Score =  159 bits (387), Expect = 2e-38
 Identities = 130/459 (28%), Positives = 212/459 (46%), Gaps = 41/459 (8%)

Query: 88  SSVGEQTLNCLRLNIYVPSAASS-RNPMPVLVWIHGGDFATGSA------SDY---GVKN 137
           S+ G++  +CL LNI+VP         +PV++WI+GG F  GS       ++Y   G + 
Sbjct: 96  STYGDE--DCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEI 153

Query: 138 IVRHGVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTI 197
             R  V+VVT NYR+GP GFL        GN GLRDQ+ A++W++ NIA+FGG+P N+T+
Sbjct: 154 ATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITL 213

Query: 198 AGQDAGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTE 256
            G+ AG  SV LQ  S  N+ L  + I +SG   S  +     +  A K+A  +G    +
Sbjct: 214 FGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGD 273

Query: 257 TEEAIQFLTKTSPDLVVAAAKE--LELQLKPCRERSFSGI--SNFVESDPYSL----TNK 308
                Q L  T P  +  A K     L+        F  +   +F+ +DP +L     + 
Sbjct: 274 AARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADI 333

Query: 309 KKVRNTPIMIGN--TNKEKKSLS-ADYFSTDPFYEKLKSNFNLDEAQIEKAAKNVRHFYI 365
             +  T  M G+   + +  +++  +   T+  + KL S F + +    + AK     Y 
Sbjct: 334 DYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGL--RGAKTTFDVYT 391

Query: 366 ---GDSSLSAEVASELQDFESDFVYNHPSQRTITQ-LLDENAGKIYEYLFSYSGELE--- 418
                          + DFE+D ++  P++  + Q   +  + K Y YLFS+   +    
Sbjct: 392 ESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYP 451

Query: 419 --DGAEHSSELNYLF--ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTI 474
              GA+H+ ++ Y+F    A  +    +++ +   +   WTNF K G+P       +PT 
Sbjct: 452 KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPN-MGDSAVPTH 510

Query: 475 WEPVTADTRPVLVLDKDVRLDSRIERQR---MAYWDLFF 510
           WEP T +    L + K +   S     R   + YW L +
Sbjct: 511 WEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTY 549


>M94579-1|AAA51973.1|  745|Homo sapiens carboxyl ester lipase
           protein.
          Length = 745

 Score =  159 bits (387), Expect = 2e-38
 Identities = 130/459 (28%), Positives = 212/459 (46%), Gaps = 41/459 (8%)

Query: 88  SSVGEQTLNCLRLNIYVPSAASS-RNPMPVLVWIHGGDFATGSA------SDY---GVKN 137
           S+ G++  +CL LNI+VP         +PV++WI+GG F  GS       ++Y   G + 
Sbjct: 96  STYGDE--DCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEI 153

Query: 138 IVRHGVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTI 197
             R  V+VVT NYR+GP GFL        GN GLRDQ+ A++W++ NIA+FGG+P N+T+
Sbjct: 154 ATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITL 213

Query: 198 AGQDAGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTE 256
            G+ AG  SV LQ  S  N+ L  + I +SG   S  +     +  A K+A  +G    +
Sbjct: 214 FGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGD 273

Query: 257 TEEAIQFLTKTSPDLVVAAAKE--LELQLKPCRERSFSGI--SNFVESDPYSL----TNK 308
                Q L  T P  +  A K     L+        F  +   +F+ +DP +L     + 
Sbjct: 274 AARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADI 333

Query: 309 KKVRNTPIMIGN--TNKEKKSLS-ADYFSTDPFYEKLKSNFNLDEAQIEKAAKNVRHFYI 365
             +  T  M G+   + +  +++  +   T+  + KL S F + +    + AK     Y 
Sbjct: 334 DYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGL--RGAKTTFDVYT 391

Query: 366 ---GDSSLSAEVASELQDFESDFVYNHPSQRTITQ-LLDENAGKIYEYLFSYSGELE--- 418
                          + DFE+D ++  P++  + Q   +  + K Y YLFS+   +    
Sbjct: 392 ESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYP 451

Query: 419 --DGAEHSSELNYLF--ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTI 474
              GA+H+ ++ Y+F    A  +    +++ +   +   WTNF K G+P       +PT 
Sbjct: 452 KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPN-MGDSAVPTH 510

Query: 475 WEPVTADTRPVLVLDKDVRLDSRIERQR---MAYWDLFF 510
           WEP T +    L + K +   S     R   + YW L +
Sbjct: 511 WEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTY 549


>M85201-1|AAA52014.1|  747|Homo sapiens cholesterol esterase
           protein.
          Length = 747

 Score =  159 bits (387), Expect = 2e-38
 Identities = 130/459 (28%), Positives = 212/459 (46%), Gaps = 41/459 (8%)

Query: 88  SSVGEQTLNCLRLNIYVPSAASS-RNPMPVLVWIHGGDFATGSA------SDY---GVKN 137
           S+ G++  +CL LNI+VP         +PV++WI+GG F  GS       ++Y   G + 
Sbjct: 96  STYGDE--DCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEI 153

Query: 138 IVRHGVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTI 197
             R  V+VVT NYR+GP GFL        GN GLRDQ+ A++W++ NIA+FGG+P N+T+
Sbjct: 154 ATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITL 213

Query: 198 AGQDAGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTE 256
            G+ AG  SV LQ  S  N+ L  + I +SG   S  +     +  A K+A  +G    +
Sbjct: 214 FGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGD 273

Query: 257 TEEAIQFLTKTSPDLVVAAAKE--LELQLKPCRERSFSGI--SNFVESDPYSL----TNK 308
                Q L  T P  +  A K     L+        F  +   +F+ +DP +L     + 
Sbjct: 274 AARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADI 333

Query: 309 KKVRNTPIMIGN--TNKEKKSLS-ADYFSTDPFYEKLKSNFNLDEAQIEKAAKNVRHFYI 365
             +  T  M G+   + +  +++  +   T+  + KL S F + +    + AK     Y 
Sbjct: 334 DYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGL--RGAKTTFDVYT 391

Query: 366 ---GDSSLSAEVASELQDFESDFVYNHPSQRTITQ-LLDENAGKIYEYLFSYSGELE--- 418
                          + DFE+D ++  P++  + Q   +  + K Y YLFS+   +    
Sbjct: 392 ESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYP 451

Query: 419 --DGAEHSSELNYLF--ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTI 474
              GA+H+ ++ Y+F    A  +    +++ +   +   WTNF K G+P       +PT 
Sbjct: 452 KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPN-MGDSAVPTH 510

Query: 475 WEPVTADTRPVLVLDKDVRLDSRIERQR---MAYWDLFF 510
           WEP T +    L + K +   S     R   + YW L +
Sbjct: 511 WEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTY 549


>M54994-1|AAA63211.1|  742|Homo sapiens bile salt-activated lipase
           protein.
          Length = 742

 Score =  159 bits (387), Expect = 2e-38
 Identities = 130/459 (28%), Positives = 212/459 (46%), Gaps = 41/459 (8%)

Query: 88  SSVGEQTLNCLRLNIYVPSAASS-RNPMPVLVWIHGGDFATGSA------SDY---GVKN 137
           S+ G++  +CL LNI+VP         +PV++WI+GG F  GS       ++Y   G + 
Sbjct: 93  STYGDE--DCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEI 150

Query: 138 IVRHGVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTI 197
             R  V+VVT NYR+GP GFL        GN GLRDQ+ A++W++ NIA+FGG+P N+T+
Sbjct: 151 ATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITL 210

Query: 198 AGQDAGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTE 256
            G+ AG  SV LQ  S  N+ L  + I +SG   S  +     +  A K+A  +G    +
Sbjct: 211 FGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGD 270

Query: 257 TEEAIQFLTKTSPDLVVAAAKE--LELQLKPCRERSFSGI--SNFVESDPYSL----TNK 308
                Q L  T P  +  A K     L+        F  +   +F+ +DP +L     + 
Sbjct: 271 AARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADI 330

Query: 309 KKVRNTPIMIGN--TNKEKKSLS-ADYFSTDPFYEKLKSNFNLDEAQIEKAAKNVRHFYI 365
             +  T  M G+   + +  +++  +   T+  + KL S F + +    + AK     Y 
Sbjct: 331 DYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGL--RGAKTTFDVYT 388

Query: 366 ---GDSSLSAEVASELQDFESDFVYNHPSQRTITQ-LLDENAGKIYEYLFSYSGELE--- 418
                          + DFE+D ++  P++  + Q   +  + K Y YLFS+   +    
Sbjct: 389 ESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYP 448

Query: 419 --DGAEHSSELNYLF--ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTI 474
              GA+H+ ++ Y+F    A  +    +++ +   +   WTNF K G+P       +PT 
Sbjct: 449 KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPN-MGDSAVPTH 507

Query: 475 WEPVTADTRPVLVLDKDVRLDSRIERQR---MAYWDLFF 510
           WEP T +    L + K +   S     R   + YW L +
Sbjct: 508 WEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTY 546


>AL162417-8|CAI13412.1|  756|Homo sapiens carboxyl ester lipase
           (bile salt-stimulated lipase) protein.
          Length = 756

 Score =  159 bits (387), Expect = 2e-38
 Identities = 130/459 (28%), Positives = 212/459 (46%), Gaps = 41/459 (8%)

Query: 88  SSVGEQTLNCLRLNIYVPSAASS-RNPMPVLVWIHGGDFATGSA------SDY---GVKN 137
           S+ G++  +CL LNI+VP         +PV++WI+GG F  GS       ++Y   G + 
Sbjct: 96  STYGDE--DCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEI 153

Query: 138 IVRHGVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTI 197
             R  V+VVT NYR+GP GFL        GN GLRDQ+ A++W++ NIA+FGG+P N+T+
Sbjct: 154 ATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITL 213

Query: 198 AGQDAGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTE 256
            G+ AG  SV LQ  S  N+ L  + I +SG   S  +     +  A K+A  +G    +
Sbjct: 214 FGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGD 273

Query: 257 TEEAIQFLTKTSPDLVVAAAKE--LELQLKPCRERSFSGI--SNFVESDPYSL----TNK 308
                Q L  T P  +  A K     L+        F  +   +F+ +DP +L     + 
Sbjct: 274 AARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADI 333

Query: 309 KKVRNTPIMIGN--TNKEKKSLS-ADYFSTDPFYEKLKSNFNLDEAQIEKAAKNVRHFYI 365
             +  T  M G+   + +  +++  +   T+  + KL S F + +    + AK     Y 
Sbjct: 334 DYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGL--RGAKTTFDVYT 391

Query: 366 ---GDSSLSAEVASELQDFESDFVYNHPSQRTITQ-LLDENAGKIYEYLFSYSGELE--- 418
                          + DFE+D ++  P++  + Q   +  + K Y YLFS+   +    
Sbjct: 392 ESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYP 451

Query: 419 --DGAEHSSELNYLF--ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTI 474
              GA+H+ ++ Y+F    A  +    +++ +   +   WTNF K G+P       +PT 
Sbjct: 452 KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPN-MGDSAVPTH 510

Query: 475 WEPVTADTRPVLVLDKDVRLDSRIERQR---MAYWDLFF 510
           WEP T +    L + K +   S     R   + YW L +
Sbjct: 511 WEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTY 549


>AF081673-1|AAC71012.1|  612|Homo sapiens bile salt-dependent lipase
           oncofetal isoform protein.
          Length = 612

 Score =  159 bits (387), Expect = 2e-38
 Identities = 130/459 (28%), Positives = 212/459 (46%), Gaps = 41/459 (8%)

Query: 88  SSVGEQTLNCLRLNIYVPSAASS-RNPMPVLVWIHGGDFATGSA------SDY---GVKN 137
           S+ G++  +CL LNI+VP         +PV++WI+GG F  GS       ++Y   G + 
Sbjct: 73  STYGDE--DCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEI 130

Query: 138 IVRHGVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTI 197
             R  V+VVT NYR+GP GFL        GN GLRDQ+ A++W++ NIA+FGG+P N+T+
Sbjct: 131 ATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITL 190

Query: 198 AGQDAGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTE 256
            G+ AG  SV LQ  S  N+ L  + I +SG   S  +     +  A K+A  +G    +
Sbjct: 191 FGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGD 250

Query: 257 TEEAIQFLTKTSPDLVVAAAKE--LELQLKPCRERSFSGI--SNFVESDPYSL----TNK 308
                Q L  T P  +  A K     L+        F  +   +F+ +DP +L     + 
Sbjct: 251 AARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADI 310

Query: 309 KKVRNTPIMIGN--TNKEKKSLS-ADYFSTDPFYEKLKSNFNLDEAQIEKAAKNVRHFYI 365
             +  T  M G+   + +  +++  +   T+  + KL S F + +    + AK     Y 
Sbjct: 311 DYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGL--RGAKTTFDVYT 368

Query: 366 ---GDSSLSAEVASELQDFESDFVYNHPSQRTITQ-LLDENAGKIYEYLFSYSGELE--- 418
                          + DFE+D ++  P++  + Q   +  + K Y YLFS+   +    
Sbjct: 369 ESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYP 428

Query: 419 --DGAEHSSELNYLF--ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTI 474
              GA+H+ ++ Y+F    A  +    +++ +   +   WTNF K G+P       +PT 
Sbjct: 429 KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPN-MGDSAVPTH 487

Query: 475 WEPVTADTRPVLVLDKDVRLDSRIERQR---MAYWDLFF 510
           WEP T +    L + K +   S     R   + YW L +
Sbjct: 488 WEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTY 526


>AF072711-1|AAC26514.1|  745|Homo sapiens carboxyl ester lipase
           protein.
          Length = 745

 Score =  159 bits (387), Expect = 2e-38
 Identities = 130/459 (28%), Positives = 212/459 (46%), Gaps = 41/459 (8%)

Query: 88  SSVGEQTLNCLRLNIYVPSAASS-RNPMPVLVWIHGGDFATGSA------SDY---GVKN 137
           S+ G++  +CL LNI+VP         +PV++WI+GG F  GS       ++Y   G + 
Sbjct: 96  STYGDE--DCLYLNIWVPQGRKQVSRDLPVMIWIYGGAFLMGSGHGANFLNNYLYDGEEI 153

Query: 138 IVRHGVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTI 197
             R  V+VVT NYR+GP GFL        GN GLRDQ+ A++W++ NIA+FGG+P N+T+
Sbjct: 154 ATRGNVIVVTFNYRVGPLGFLSTGDANLPGNYGLRDQHMAIAWVKRNIAAFGGDPNNITL 213

Query: 198 AGQDAGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTE 256
            G+ AG  SV LQ  S  N+ L  + I +SG   S  +     +  A K+A  +G    +
Sbjct: 214 FGESAGGASVSLQTLSPYNKGLIRRAISQSGVALSPWVIQKNPLFWAKKVAEKVGCPVGD 273

Query: 257 TEEAIQFLTKTSPDLVVAAAKE--LELQLKPCRERSFSGI--SNFVESDPYSL----TNK 308
                Q L  T P  +  A K     L+        F  +   +F+ +DP +L     + 
Sbjct: 274 AARMAQCLKVTDPRALTLAYKVPLAGLEYPMLHYVGFVPVIDGDFIPADPINLYANAADI 333

Query: 309 KKVRNTPIMIGN--TNKEKKSLS-ADYFSTDPFYEKLKSNFNLDEAQIEKAAKNVRHFYI 365
             +  T  M G+   + +  +++  +   T+  + KL S F + +    + AK     Y 
Sbjct: 334 DYIAGTNNMDGHIFASIDMPAINKGNKKVTEEDFYKLVSEFTITKGL--RGAKTTFDVYT 391

Query: 366 ---GDSSLSAEVASELQDFESDFVYNHPSQRTITQ-LLDENAGKIYEYLFSYSGELE--- 418
                          + DFE+D ++  P++  + Q   +  + K Y YLFS+   +    
Sbjct: 392 ESWAQDPSQENKKKTVVDFETDVLFLVPTEIALAQHRANAKSAKTYAYLFSHPSRMPVYP 451

Query: 419 --DGAEHSSELNYLF--ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTI 474
              GA+H+ ++ Y+F    A  +    +++ +   +   WTNF K G+P       +PT 
Sbjct: 452 KWVGADHADDIQYVFGKPFATPTGYRPQDRTVSKAMIAYWTNFAKTGDPN-MGDSAVPTH 510

Query: 475 WEPVTADTRPVLVLDKDVRLDSRIERQR---MAYWDLFF 510
           WEP T +    L + K +   S     R   + YW L +
Sbjct: 511 WEPYTTENSGYLEITKKMGSSSMKRSLRTNFLRYWTLTY 549


>M55040-1|AAA68151.1|  614|Homo sapiens acetylcholinesterase
           protein.
          Length = 614

 Score =  157 bits (380), Expect = 1e-37
 Identities = 147/531 (27%), Positives = 236/531 (44%), Gaps = 49/531 (9%)

Query: 25  LVLISNQGLVRGH--KAADGDYSIFLGIPYAKVDVN----------NPFSTATDPIAFPE 72
           L++    G +RG   K   G  S FLGIP+A+  +            P+S   D   F  
Sbjct: 39  LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98

Query: 73  IIHDAVDEVRCPQTSSSVG----EQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATG 128
           + +  VD +      + +     E + +CL LN++ P    + +P PVLVWI+GG F +G
Sbjct: 99  VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVLVWIYGGGFYSG 157

Query: 129 SAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDVPT-ASGNQGLRDQYKALSWIRNN 184
           ++S   Y  + +V+    ++V+MNYR+G +GFL L     A GN GL DQ  AL W++ N
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

Query: 185 IASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTPQSEGMFVNADV--E 241
           +A+FGG+P +VT+ G+ AGA SV + L S   + LFH+ +++SG P      V       
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277

Query: 242 AAIKLAVHLGL---NTTETEEAIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGI--SN 296
            A +LA  +G     T   +  +    +T P  V+   +   L  +     SF  +   +
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337

Query: 297 FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---SADYFSTDPFYEKLKSNF----NLD 349
           F+   P +L N        +++G    E        A  FS D      ++ F     + 
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVG 397

Query: 350 EAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDFVYNHPSQRTITQL---LDENAGKI 406
             Q+   A      +  D  L  E  + L++  SD V +H     + QL   L     ++
Sbjct: 398 VPQVSDLAAEAVVLHYTD-WLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARV 456

Query: 407 YEYLFSY-----SGELEDGAEHSSELNYLFETAGGSDR--TEEEQLMVDRITTLWTNFVK 459
           Y Y+F +     S  L  G  H  E+ ++F       R  T EE++   R+   W NF +
Sbjct: 457 YAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFAR 516

Query: 460 FGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSRIERQRMAYWDLF 509
            G+P        P  W P TA  +  + LD + + +   +  Q  A+W+ F
Sbjct: 517 TGDPNEPRDPKAPQ-WPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 566


>BC105062-1|AAI05063.1|  617|Homo sapiens acetylcholinesterase,
           isoform E4-E5 precursor protein.
          Length = 617

 Score =  157 bits (380), Expect = 1e-37
 Identities = 147/531 (27%), Positives = 236/531 (44%), Gaps = 49/531 (9%)

Query: 25  LVLISNQGLVRGH--KAADGDYSIFLGIPYAKVDVN----------NPFSTATDPIAFPE 72
           L++    G +RG   K   G  S FLGIP+A+  +            P+S   D   F  
Sbjct: 39  LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98

Query: 73  IIHDAVDEVRCPQTSSSVG----EQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATG 128
           + +  VD +      + +     E + +CL LN++ P    + +P PVLVWI+GG F +G
Sbjct: 99  VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVLVWIYGGGFYSG 157

Query: 129 SAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDVPT-ASGNQGLRDQYKALSWIRNN 184
           ++S   Y  + +V+    ++V+MNYR+G +GFL L     A GN GL DQ  AL W++ N
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

Query: 185 IASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTPQSEGMFVNADV--E 241
           +A+FGG+P +VT+ G+ AGA SV + L S   + LFH+ +++SG P      V       
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277

Query: 242 AAIKLAVHLGL---NTTETEEAIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGI--SN 296
            A +LA  +G     T   +  +    +T P  V+   +   L  +     SF  +   +
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337

Query: 297 FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---SADYFSTDPFYEKLKSNF----NLD 349
           F+   P +L N        +++G    E        A  FS D      ++ F     + 
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVG 397

Query: 350 EAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDFVYNHPSQRTITQL---LDENAGKI 406
             Q+   A      +  D  L  E  + L++  SD V +H     + QL   L     ++
Sbjct: 398 VPQVSDLAAEAVVLHYTD-WLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARV 456

Query: 407 YEYLFSY-----SGELEDGAEHSSELNYLFETAGGSDR--TEEEQLMVDRITTLWTNFVK 459
           Y Y+F +     S  L  G  H  E+ ++F       R  T EE++   R+   W NF +
Sbjct: 457 YAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFAR 516

Query: 460 FGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSRIERQRMAYWDLF 509
            G+P        P  W P TA  +  + LD + + +   +  Q  A+W+ F
Sbjct: 517 TGDPNEPRDPKAPQ-WPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 566


>BC105060-1|AAI05061.1|  617|Homo sapiens acetylcholinesterase (Yt
           blood group) protein.
          Length = 617

 Score =  157 bits (380), Expect = 1e-37
 Identities = 147/531 (27%), Positives = 236/531 (44%), Gaps = 49/531 (9%)

Query: 25  LVLISNQGLVRGH--KAADGDYSIFLGIPYAKVDVN----------NPFSTATDPIAFPE 72
           L++    G +RG   K   G  S FLGIP+A+  +            P+S   D   F  
Sbjct: 39  LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98

Query: 73  IIHDAVDEVRCPQTSSSVG----EQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATG 128
           + +  VD +      + +     E + +CL LN++ P    + +P PVLVWI+GG F +G
Sbjct: 99  VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVLVWIYGGGFYSG 157

Query: 129 SAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDVPT-ASGNQGLRDQYKALSWIRNN 184
           ++S   Y  + +V+    ++V+MNYR+G +GFL L     A GN GL DQ  AL W++ N
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

Query: 185 IASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTPQSEGMFVNADV--E 241
           +A+FGG+P +VT+ G+ AGA SV + L S   + LFH+ +++SG P      V       
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277

Query: 242 AAIKLAVHLGL---NTTETEEAIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGI--SN 296
            A +LA  +G     T   +  +    +T P  V+   +   L  +     SF  +   +
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337

Query: 297 FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---SADYFSTDPFYEKLKSNF----NLD 349
           F+   P +L N        +++G    E        A  FS D      ++ F     + 
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVG 397

Query: 350 EAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDFVYNHPSQRTITQL---LDENAGKI 406
             Q+   A      +  D  L  E  + L++  SD V +H     + QL   L     ++
Sbjct: 398 VPQVSDLAAEAVVLHYTD-WLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARV 456

Query: 407 YEYLFSY-----SGELEDGAEHSSELNYLFETAGGSDR--TEEEQLMVDRITTLWTNFVK 459
           Y Y+F +     S  L  G  H  E+ ++F       R  T EE++   R+   W NF +
Sbjct: 457 YAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFAR 516

Query: 460 FGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSRIERQRMAYWDLF 509
            G+P        P  W P TA  +  + LD + + +   +  Q  A+W+ F
Sbjct: 517 TGDPNEPRDPKAPQ-WPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 566


>AY750146-1|AAU43801.1|  617|Homo sapiens acetylcholinesterase (YT
           blood group) protein.
          Length = 617

 Score =  157 bits (380), Expect = 1e-37
 Identities = 147/531 (27%), Positives = 236/531 (44%), Gaps = 49/531 (9%)

Query: 25  LVLISNQGLVRGH--KAADGDYSIFLGIPYAKVDVN----------NPFSTATDPIAFPE 72
           L++    G +RG   K   G  S FLGIP+A+  +            P+S   D   F  
Sbjct: 39  LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98

Query: 73  IIHDAVDEVRCPQTSSSVG----EQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATG 128
           + +  VD +      + +     E + +CL LN++ P    + +P PVLVWI+GG F +G
Sbjct: 99  VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVLVWIYGGGFYSG 157

Query: 129 SAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDVPT-ASGNQGLRDQYKALSWIRNN 184
           ++S   Y  + +V+    ++V+MNYR+G +GFL L     A GN GL DQ  AL W++ N
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

Query: 185 IASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTPQSEGMFVNADV--E 241
           +A+FGG+P +VT+ G+ AGA SV + L S   + LFH+ +++SG P      V       
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277

Query: 242 AAIKLAVHLGL---NTTETEEAIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGI--SN 296
            A +LA  +G     T   +  +    +T P  V+   +   L  +     SF  +   +
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337

Query: 297 FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---SADYFSTDPFYEKLKSNF----NLD 349
           F+   P +L N        +++G    E        A  FS D      ++ F     + 
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVG 397

Query: 350 EAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDFVYNHPSQRTITQL---LDENAGKI 406
             Q+   A      +  D  L  E  + L++  SD V +H     + QL   L     ++
Sbjct: 398 VPQVSDLAAEAVVLHYTD-WLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARV 456

Query: 407 YEYLFSY-----SGELEDGAEHSSELNYLFETAGGSDR--TEEEQLMVDRITTLWTNFVK 459
           Y Y+F +     S  L  G  H  E+ ++F       R  T EE++   R+   W NF +
Sbjct: 457 YAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFAR 516

Query: 460 FGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSRIERQRMAYWDLF 509
            G+P        P  W P TA  +  + LD + + +   +  Q  A+W+ F
Sbjct: 517 TGDPNEPRDPKAPQ-WPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 566


>AK223443-1|BAD97163.1|  614|Homo sapiens acetylcholinesterase
           isoform E4-E6 precursor variant protein.
          Length = 614

 Score =  157 bits (380), Expect = 1e-37
 Identities = 150/534 (28%), Positives = 239/534 (44%), Gaps = 55/534 (10%)

Query: 25  LVLISNQGLVRGH--KAADGDYSIFLGIPYAKVDVN----------NPFSTATDPIAFPE 72
           L++    G +RG   K   G  S FLGIP+A+  +            P+S   D   F  
Sbjct: 39  LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98

Query: 73  IIHDAVDEVRCPQTSSSVG----EQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATG 128
           + +  VD +      + +     E + +CL LN++ P    + +P PVLVWI+GG F +G
Sbjct: 99  VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVLVWIYGGGFYSG 157

Query: 129 SAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDVPT-ASGNQGLRDQYKALSWIRNN 184
           ++S   Y  + +V+    ++V+MNYR+G +GFL L     A GN GL DQ  AL W++ N
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

Query: 185 IASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTPQSEGMFVN-ADVEA 242
           +A+FGG+P +VT+ G+ AGA SV + L S   + LFH+ +++SG P      V   +   
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277

Query: 243 AIKLAVHL------GLNTTETEEAIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGI-- 294
                 HL      G    +TE  +    +T P  V+   +   L  +     SF  +  
Sbjct: 278 RTTQLAHLVGCPPGGTGGNDTE--LVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVD 335

Query: 295 SNFVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---SADYFSTDPFYEKLKSNF----N 347
            +F+   P +L N        +++G    E        A  FS D      ++ F     
Sbjct: 336 GDFLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVR 395

Query: 348 LDEAQI-EKAAKNVRHFYIGDSSLSAEVASELQDFESDFVYNHPSQRTITQL---LDENA 403
           +   Q+ + AA+ V   Y G   L  E  + L++  SD V +H     + QL   L    
Sbjct: 396 VGVPQVSDLAAEAVVLHYTG--WLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQG 453

Query: 404 GKIYEYLFSY-----SGELEDGAEHSSELNYLFETAGGSDR--TEEEQLMVDRITTLWTN 456
            ++Y Y+F +     S  L  G  H  E+ ++F       R  T EE++   R+   W N
Sbjct: 454 ARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWAN 513

Query: 457 FVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSRIERQRMAYWDLF 509
           F + G+P        P  W P TA  +  + LD + + +   +  Q  A+W+ F
Sbjct: 514 FARTGDPNEPRDPKAPQ-WPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 566


>AC011895-2|AAP22364.1|  617|Homo sapiens unknown protein.
          Length = 617

 Score =  157 bits (380), Expect = 1e-37
 Identities = 147/531 (27%), Positives = 236/531 (44%), Gaps = 49/531 (9%)

Query: 25  LVLISNQGLVRGH--KAADGDYSIFLGIPYAKVDVN----------NPFSTATDPIAFPE 72
           L++    G +RG   K   G  S FLGIP+A+  +            P+S   D   F  
Sbjct: 39  LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98

Query: 73  IIHDAVDEVRCPQTSSSVG----EQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATG 128
           + +  VD +      + +     E + +CL LN++ P    + +P PVLVWI+GG F +G
Sbjct: 99  VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVLVWIYGGGFYSG 157

Query: 129 SAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDVPT-ASGNQGLRDQYKALSWIRNN 184
           ++S   Y  + +V+    ++V+MNYR+G +GFL L     A GN GL DQ  AL W++ N
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

Query: 185 IASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTPQSEGMFVNADV--E 241
           +A+FGG+P +VT+ G+ AGA SV + L S   + LFH+ +++SG P      V       
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277

Query: 242 AAIKLAVHLGL---NTTETEEAIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGI--SN 296
            A +LA  +G     T   +  +    +T P  V+   +   L  +     SF  +   +
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337

Query: 297 FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---SADYFSTDPFYEKLKSNF----NLD 349
           F+   P +L N        +++G    E        A  FS D      ++ F     + 
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVG 397

Query: 350 EAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDFVYNHPSQRTITQL---LDENAGKI 406
             Q+   A      +  D  L  E  + L++  SD V +H     + QL   L     ++
Sbjct: 398 VPQVSDLAAEAVVLHYTD-WLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARV 456

Query: 407 YEYLFSY-----SGELEDGAEHSSELNYLFETAGGSDR--TEEEQLMVDRITTLWTNFVK 459
           Y Y+F +     S  L  G  H  E+ ++F       R  T EE++   R+   W NF +
Sbjct: 457 YAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFAR 516

Query: 460 FGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSRIERQRMAYWDLF 509
            G+P        P  W P TA  +  + LD + + +   +  Q  A+W+ F
Sbjct: 517 TGDPNEPRDPKAPQ-WPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 566


>AC011895-1|AAP22365.1|  614|Homo sapiens unknown protein.
          Length = 614

 Score =  157 bits (380), Expect = 1e-37
 Identities = 147/531 (27%), Positives = 236/531 (44%), Gaps = 49/531 (9%)

Query: 25  LVLISNQGLVRGH--KAADGDYSIFLGIPYAKVDVN----------NPFSTATDPIAFPE 72
           L++    G +RG   K   G  S FLGIP+A+  +            P+S   D   F  
Sbjct: 39  LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98

Query: 73  IIHDAVDEVRCPQTSSSVG----EQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATG 128
           + +  VD +      + +     E + +CL LN++ P    + +P PVLVWI+GG F +G
Sbjct: 99  VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVLVWIYGGGFYSG 157

Query: 129 SAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDVPT-ASGNQGLRDQYKALSWIRNN 184
           ++S   Y  + +V+    ++V+MNYR+G +GFL L     A GN GL DQ  AL W++ N
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

Query: 185 IASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTPQSEGMFVNADV--E 241
           +A+FGG+P +VT+ G+ AGA SV + L S   + LFH+ +++SG P      V       
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277

Query: 242 AAIKLAVHLGL---NTTETEEAIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGI--SN 296
            A +LA  +G     T   +  +    +T P  V+   +   L  +     SF  +   +
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337

Query: 297 FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---SADYFSTDPFYEKLKSNF----NLD 349
           F+   P +L N        +++G    E        A  FS D      ++ F     + 
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVG 397

Query: 350 EAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDFVYNHPSQRTITQL---LDENAGKI 406
             Q+   A      +  D  L  E  + L++  SD V +H     + QL   L     ++
Sbjct: 398 VPQVSDLAAEAVVLHYTD-WLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARV 456

Query: 407 YEYLFSY-----SGELEDGAEHSSELNYLFETAGGSDR--TEEEQLMVDRITTLWTNFVK 459
           Y Y+F +     S  L  G  H  E+ ++F       R  T EE++   R+   W NF +
Sbjct: 457 YAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFAR 516

Query: 460 FGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSRIERQRMAYWDLF 509
            G+P        P  W P TA  +  + LD + + +   +  Q  A+W+ F
Sbjct: 517 TGDPNEPRDPKAPQ-WPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 566


>BC094752-1|AAH94752.1|  640|Homo sapiens ACHE protein protein.
          Length = 640

 Score =  156 bits (378), Expect = 2e-37
 Identities = 146/531 (27%), Positives = 236/531 (44%), Gaps = 49/531 (9%)

Query: 25  LVLISNQGLVRGH--KAADGDYSIFLGIPYAKVDVN----------NPFSTATDPIAFPE 72
           L++    G +RG   K   G  S FLGIP+A+  +            P+S   D   F  
Sbjct: 39  LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98

Query: 73  IIHDAVDEVRCPQTSSSVG----EQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATG 128
           + +  VD +      + +     E + +CL LN++ P    + +P PV+VWI+GG F +G
Sbjct: 99  VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVIVWIYGGGFYSG 157

Query: 129 SAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDVPT-ASGNQGLRDQYKALSWIRNN 184
           ++S   Y  + +V+    ++V+MNYR+G +GFL L     A GN GL DQ  AL W++ N
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

Query: 185 IASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTPQSEGMFVNADV--E 241
           +A+FGG+P +VT+ G+ AGA SV + L S   + LFH+ +++SG P      V       
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277

Query: 242 AAIKLAVHLGL---NTTETEEAIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGI--SN 296
            A +LA  +G     T   +  +    +T P  V+   +   L  +     SF  +   +
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337

Query: 297 FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---SADYFSTDPFYEKLKSNF----NLD 349
           F+   P +L N        +++G    E        A  FS D      ++ F     + 
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVG 397

Query: 350 EAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDFVYNHPSQRTITQL---LDENAGKI 406
             Q+   A      +  D  L  E  + L++  SD V +H     + QL   L     ++
Sbjct: 398 VPQVSDLAAEAVVLHYTD-WLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARV 456

Query: 407 YEYLFSY-----SGELEDGAEHSSELNYLFETAGGSDR--TEEEQLMVDRITTLWTNFVK 459
           Y Y+F +     S  L  G  H  E+ ++F       R  T EE++   R+   W NF +
Sbjct: 457 YAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFAR 516

Query: 460 FGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSRIERQRMAYWDLF 509
            G+P        P  W P TA  +  + LD + + +   +  Q  A+W+ F
Sbjct: 517 TGDPNEPRDPKAPQ-WPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 566


>AY268104-1|AAP20868.1|  567|Homo sapiens cholesteryl ester
           hydrolase protein.
          Length = 567

 Score =  154 bits (374), Expect = 6e-37
 Identities = 140/509 (27%), Positives = 222/509 (43%), Gaps = 48/509 (9%)

Query: 45  SIFLGIPYAKVDVNNPFSTATDPIAFPEIIHDAVDE----VRCPQTSSSVGEQTLN---- 96
           +IFLGIP+AK  +    ST   P      + +A        R P+    + E   N    
Sbjct: 48  AIFLGIPFAKPPLGPLRSTPPQPAEPWSFVKNATSYPPMCTRDPKAGQLLSELFTNRKEN 107

Query: 97  --------CLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVT 147
                   CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT
Sbjct: 108 IPLKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVT 167

Query: 148 MNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV 207
           + YRLG +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV
Sbjct: 168 IQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESV 227

Query: 208 LLQLYSDNEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL- 264
            + + S   K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L 
Sbjct: 228 SVLVLSPLAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLR 287

Query: 265 TKTSPDLVVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIM 317
            KT  +L+    K     L+LQ  P   +   G       +   P  L  ++     P M
Sbjct: 288 QKTEEELLETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYM 347

Query: 318 IGNTNKE-----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDS 368
           +G   +E        L +   S     +K   +       +   AK +       Y+G +
Sbjct: 348 VGINKQEFGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGT 407

Query: 369 SLSAEVASELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AE 422
             + +      D  +D ++  PS        D  A   +YE+ +  S+S +++      +
Sbjct: 408 DDTVKKKDLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGD 467

Query: 423 HSSELNYLFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTAD 481
           H  EL  +F      +   EE++ + + +   W NF + GNP  +    +P  W P    
Sbjct: 468 HGDELFSVFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQ 522

Query: 482 TRPVLVLDKDVRLDSRIERQRMAYWDLFF 510
               L +  + +   +++ + +A+W   F
Sbjct: 523 KEGYLQIGANTQAAQKLKDKEVAFWTNLF 551


>M65261-1|AAA83932.1|  454|Homo sapiens carboxylesterase protein.
          Length = 454

 Score =  153 bits (370), Expect = 2e-36
 Identities = 125/442 (28%), Positives = 203/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 2   HCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 61

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 62  WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 121

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 122 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAAMVHCLRQKTEEEL 181

Query: 272 VVAAAKELELQLKPCRE--RSFSGISNFVE-----SDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L   RE  R  + +   ++       P  L  ++     P M+G   +E
Sbjct: 182 LETTLKIGNSYLWTYRETQRESTLLGTVIDGMLLLKTPEELQRERNFHTVPYMVGINKQE 241

Query: 325 KKSLSADYFSTDPFYE---KLKSNFNLDEAQI------EKAAKNVRHFYIGDSSLSAEVA 375
              L      + P  E     K+  +L  + I      ++        Y+G +  + +  
Sbjct: 242 FGWLIPMQLMSYPLSEGQLDQKTAMSLLGSPIPLFAIAKELIPEATEKYLGGTDDTVKKK 301

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
             + D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 302 DLILDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 361

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  K    +P  W P        L +
Sbjct: 362 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGKG---LPH-W-PEYNQKEGYLQI 416

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 417 GANTQAAQKLKDKEVAFWTNLF 438


>BC117126-1|AAI17127.1|  575|Homo sapiens CES7 protein protein.
          Length = 575

 Score =  152 bits (369), Expect = 3e-36
 Identities = 137/435 (31%), Positives = 206/435 (47%), Gaps = 39/435 (8%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRH-GVLVVTMNYRLGP 154
           +CL LNIY P+ A + + +PVLVW  GG F TGSAS +    +  +  VLVV + YRLG 
Sbjct: 120 DCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGI 179

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       A GN   +DQ  ALSW++ NI  FGG+P +VTI G+ AGA SV   + S 
Sbjct: 180 FGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSP 239

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVEAA--IKLAVHLGLNTTETEEAIQFLTKTSPDL 271
             K LFHK I+ESG      +  + D E +  +++  H   N     EA+    +T P  
Sbjct: 240 MAKGLFHKAIMESGVAIIPYLEAH-DYEKSEDLQVVAHFCGNNASDSEALLRCLRTKP-- 296

Query: 272 VVAAAKELELQLKPCRERSFSGISN--FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSLS 329
               +KEL L L   + +SF+ + +  F  ++P  L ++K  +  P +IG  N E   L 
Sbjct: 297 ----SKEL-LTLSQ-KTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLL 350

Query: 330 ADYFSTDPFYEKLKS-NFNLDEAQIE---KAAKNVRHFYIGDSSLSAEVASELQDFESDF 385
               + +      KS   +L +  +    +    V + Y  D     E+   L D   D 
Sbjct: 351 PMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDV 410

Query: 386 VYNHPSQRTITQLLDENAGKIYEYLFSYSGE-LED------GAEHSSELNYLFETA---G 435
            +  P+  T     D  A  +Y Y F +  +  ED       A+H+ E+ ++F  A   G
Sbjct: 411 FFVVPALITARYHRDAGA-PVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKG 469

Query: 436 G----SDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDKD 491
                   TEEE+L+  ++   W  F + GN  P   DL  ++W P    T   L LD +
Sbjct: 470 DIVMFEGATEEEKLLSRKMMKYWATFARTGN--PNGNDL--SLW-PAYNLTEQYLQLDLN 524

Query: 492 VRLDSRIERQRMAYW 506
           + L  R++  R+ +W
Sbjct: 525 MSLGQRLKEPRVDFW 539


>BC069501-1|AAH69501.1|  575|Homo sapiens CES7 protein protein.
          Length = 575

 Score =  152 bits (369), Expect = 3e-36
 Identities = 137/435 (31%), Positives = 206/435 (47%), Gaps = 39/435 (8%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRH-GVLVVTMNYRLGP 154
           +CL LNIY P+ A + + +PVLVW  GG F TGSAS +    +  +  VLVV + YRLG 
Sbjct: 120 DCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGI 179

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       A GN   +DQ  ALSW++ NI  FGG+P +VTI G+ AGA SV   + S 
Sbjct: 180 FGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSP 239

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVEAA--IKLAVHLGLNTTETEEAIQFLTKTSPDL 271
             K LFHK I+ESG      +  + D E +  +++  H   N     EA+    +T P  
Sbjct: 240 MAKGLFHKAIMESGVAIIPYLEAH-DYEKSEDLQVVAHFCGNNASDSEALLRCLRTKP-- 296

Query: 272 VVAAAKELELQLKPCRERSFSGISN--FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSLS 329
               +KEL L L   + +SF+ + +  F  ++P  L ++K  +  P +IG  N E   L 
Sbjct: 297 ----SKEL-LTLSQ-KTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLL 350

Query: 330 ADYFSTDPFYEKLKS-NFNLDEAQIE---KAAKNVRHFYIGDSSLSAEVASELQDFESDF 385
               + +      KS   +L +  +    +    V + Y  D     E+   L D   D 
Sbjct: 351 PMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDV 410

Query: 386 VYNHPSQRTITQLLDENAGKIYEYLFSYSGE-LED------GAEHSSELNYLFETA---G 435
            +  P+  T     D  A  +Y Y F +  +  ED       A+H+ E+ ++F  A   G
Sbjct: 411 FFVVPALITARYHRDAGA-PVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKG 469

Query: 436 G----SDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDKD 491
                   TEEE+L+  ++   W  F + GN  P   DL  ++W P    T   L LD +
Sbjct: 470 DIVMFEGATEEEKLLSRKMMKYWATFARTGN--PNGNDL--SLW-PAYNLTEQYLQLDLN 524

Query: 492 VRLDSRIERQRMAYW 506
           + L  R++  R+ +W
Sbjct: 525 MSLGQRLKEPRVDFW 539


>AY907669-1|AAX86044.1|  575|Homo sapiens carboxylesterase 5
           protein.
          Length = 575

 Score =  152 bits (369), Expect = 3e-36
 Identities = 137/435 (31%), Positives = 206/435 (47%), Gaps = 39/435 (8%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRH-GVLVVTMNYRLGP 154
           +CL LNIY P+ A + + +PVLVW  GG F TGSAS +    +  +  VLVV + YRLG 
Sbjct: 120 DCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGI 179

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       A GN   +DQ  ALSW++ NI  FGG+P +VTI G+ AGA SV   + S 
Sbjct: 180 FGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSP 239

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVEAA--IKLAVHLGLNTTETEEAIQFLTKTSPDL 271
             K LFHK I+ESG      +  + D E +  +++  H   N     EA+    +T P  
Sbjct: 240 MAKGLFHKAIMESGVAIIPYLEAH-DYEKSEDLQVVAHFCGNNASDSEALLRCLRTKP-- 296

Query: 272 VVAAAKELELQLKPCRERSFSGISN--FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSLS 329
               +KEL L L   + +SF+ + +  F  ++P  L ++K  +  P +IG  N E   L 
Sbjct: 297 ----SKEL-LTLSQ-KTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHECGFLL 350

Query: 330 ADYFSTDPFYEKLKS-NFNLDEAQIE---KAAKNVRHFYIGDSSLSAEVASELQDFESDF 385
               + +      KS   +L +  +    +    V + Y  D     E+   L D   D 
Sbjct: 351 PMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDV 410

Query: 386 VYNHPSQRTITQLLDENAGKIYEYLFSYSGE-LED------GAEHSSELNYLFETA---G 435
            +  P+  T     D  A  +Y Y F +  +  ED       A+H+ E+ ++F  A   G
Sbjct: 411 FFVVPALITARYHRDAGA-PVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKG 469

Query: 436 G----SDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDKD 491
                   TEEE+L+  ++   W  F + GN  P   DL  ++W P    T   L LD +
Sbjct: 470 DIVMFEGATEEEKLLSRKMMKYWATFARTGN--PNGNDL--SLW-PAYNLTEQYLQLDLN 524

Query: 492 VRLDSRIERQRMAYW 506
           + L  R++  R+ +W
Sbjct: 525 MSLGQRLKEPRVDFW 539


>X52973-1|CAA37147.1|  503|Homo sapiens monocyte/macrophage
           serine-esterase 1 protein.
          Length = 503

 Score =  152 bits (368), Expect = 3e-36
 Identities = 125/442 (28%), Positives = 201/442 (45%), Gaps = 33/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 52  DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 111

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 112 WGFFSTGDEHSGGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 171

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 172 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 231

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G  NK+
Sbjct: 232 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVG-INKQ 290

Query: 325 KKSLSADYFSTDPFYE-----KLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
           +         + P  E     K   +       +   AK +       Y+G +  + +  
Sbjct: 291 EFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 350

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 351 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 410

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 411 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 465

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 466 GANTQAAQKLKDKEVAFWTNLF 487


>L07765-1|AAA35711.1|  566|Homo sapiens carboxylesterase protein.
          Length = 566

 Score =  152 bits (368), Expect = 3e-36
 Identities = 125/442 (28%), Positives = 201/442 (45%), Gaps = 33/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G  NK+
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVG-INKQ 353

Query: 325 KKSLSADYFSTDPFYE-----KLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
           +         + P  E     K   +       +   AK +       Y+G +  + +  
Sbjct: 354 EFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 413

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 414 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 473

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 474 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 528

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 529 GANTQAGQKLKDKEVAFWTNLF 550


>L07764-1|AAA16036.1|  568|Homo sapiens carboxylesterase protein.
          Length = 568

 Score =  152 bits (368), Expect = 3e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 116 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 175

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 176 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 235

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 236 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 295

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 296 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 355

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 356 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 415

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 416 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 475

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 476 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 530

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 531 GANTQAGQKLKDKEVAFWTNLF 552


>S73751-1|AAC60631.2|  568|Homo sapiens acyl coenzyme A:cholesterol
           acyltransferase protein.
          Length = 568

 Score =  151 bits (367), Expect = 5e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 116 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 175

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 176 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 235

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 236 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 295

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 296 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 355

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 356 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 415

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 416 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 475

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 476 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 530

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 531 GANTQAAQKLKDKEVAFWTNLF 552


>M73499-1|AAA35649.1|  567|Homo sapiens carboxylesterase protein.
          Length = 567

 Score =  151 bits (367), Expect = 5e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 355 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 414

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 415 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 474

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 475 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 529

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLF 551


>M55509-1|AAA35650.1|  507|Homo sapiens carboxylesterase protein.
          Length = 507

 Score =  151 bits (367), Expect = 5e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 55  DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 114

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 115 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 174

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 175 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 234

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 235 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 294

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 295 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 354

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 355 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 414

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 415 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 469

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 470 GANTQAAQKLKDKEVAFWTNLF 491


>D21088-1|BAA04650.1|  567|Homo sapiens carboxylesterase protein.
          Length = 567

 Score =  151 bits (367), Expect = 5e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 355 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 414

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 415 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 474

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 475 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 529

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLF 551


>BC110338-1|AAI10339.1|  567|Homo sapiens carboxylesterase 1
           (monocyte/macrophage serine esterase 1) protein.
          Length = 567

 Score =  151 bits (367), Expect = 5e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 355 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 414

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 415 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 474

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 475 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 529

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLF 551


>BC012418-1|AAH12418.1|  566|Homo sapiens carboxylesterase 1
           (monocyte/macrophage serine esterase 1) protein.
          Length = 566

 Score =  151 bits (367), Expect = 5e-36
 Identities = 125/442 (28%), Positives = 201/442 (45%), Gaps = 33/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G  NK+
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVG-INKQ 353

Query: 325 KKSLSADYFSTDPFYE-----KLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
           +         + P  E     K   +       +   AK +       Y+G +  + +  
Sbjct: 354 EFGWLIPMLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 413

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 414 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 473

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 474 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 528

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 529 GANTQAAQKLKDKEVAFWTNLF 550


>AF177775-1|AAD53175.1|  567|Homo sapiens egasyn protein.
          Length = 567

 Score =  151 bits (367), Expect = 5e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 355 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 414

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 415 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 474

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 475 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 529

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLF 551


>AB119998-1|BAC87751.1|  567|Homo sapiens carboxylesterase HU1b
           protein.
          Length = 567

 Score =  151 bits (367), Expect = 5e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 355 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 414

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 415 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 474

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 475 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 529

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLF 551


>AB119997-1|BAC87750.1|  567|Homo sapiens carboxylesterase HU1a
           protein.
          Length = 567

 Score =  151 bits (367), Expect = 5e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 355 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 414

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 415 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 474

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 475 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 529

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLF 551


>AB119996-1|BAC87749.1|  567|Homo sapiens carboxylesterase HU1b
           protein.
          Length = 567

 Score =  151 bits (367), Expect = 5e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 355 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 414

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 415 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 474

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 475 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 529

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLF 551


>AB119995-1|BAC87748.1|  567|Homo sapiens carboxylesterase HU1a
           protein.
          Length = 567

 Score =  151 bits (367), Expect = 5e-36
 Identities = 124/442 (28%), Positives = 200/442 (45%), Gaps = 32/442 (7%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354

Query: 325 -----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNV----RHFYIGDSSLSAEVA 375
                   L +   S     +K   +       +   AK +       Y+G +  + +  
Sbjct: 355 FGWLIPMQLMSYPLSEGQLDQKTAMSLLWKSYPLVCIAKELIPEATEKYLGGTDDTVKKK 414

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNY 429
               D  +D ++  PS        D  A   +YE+ +  S+S +++      +H  EL  
Sbjct: 415 DLFLDLIADVMFGVPSVIVARNHRDAGAPTYMYEFQYRPSFSSDMKPKTVIGDHGDELFS 474

Query: 430 LFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVL 488
           +F      +   EE++ + + +   W NF + GNP  +    +P  W P        L +
Sbjct: 475 VFGAPFLKEGASEEEIRLSKMVMKFWANFARNGNPNGEG---LPH-W-PEYNQKEGYLQI 529

Query: 489 DKDVRLDSRIERQRMAYWDLFF 510
             + +   +++ + +A+W   F
Sbjct: 530 GANTQAAQKLKDKEVAFWTNLF 551


>BC036813-1|AAH36813.1|  546|Homo sapiens ACHE protein protein.
          Length = 546

 Score =  151 bits (366), Expect = 6e-36
 Identities = 143/510 (28%), Positives = 226/510 (44%), Gaps = 48/510 (9%)

Query: 25  LVLISNQGLVRGH--KAADGDYSIFLGIPYAKVDVN----------NPFSTATDPIAFPE 72
           L++    G +RG   K   G  S FLGIP+A+  +            P+S   D   F  
Sbjct: 39  LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98

Query: 73  IIHDAVDEVRCPQTSSSVG----EQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATG 128
           + +  VD +      + +     E + +CL LN++ P    + +P PVLVWI+GG F +G
Sbjct: 99  VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVLVWIYGGGFYSG 157

Query: 129 SAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDVPT-ASGNQGLRDQYKALSWIRNN 184
           ++S   Y  + +V+    ++V+MNYR+G +GFL L     A GN GL DQ  AL W++ N
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

Query: 185 IASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTPQSEGMFVNADV--E 241
           +A+FGG+P +VT+ G+ AGA SV + L S   + LFH+ +++SG P      V       
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAPNGPWATVGMGEARR 277

Query: 242 AAIKLAVHLGL---NTTETEEAIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGI--SN 296
            A +LA  +G     T   +  +    +T P  V+   +   L  +     SF  +   +
Sbjct: 278 RATQLAHLVGCPPGGTGGNDTELVACLRTRPAQVLVNHEWHVLPQESVFRFSFVPVVDGD 337

Query: 297 FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---SADYFSTDPFYEKLKSNF----NLD 349
           F+   P +L N        +++G    E        A  FS D      ++ F     + 
Sbjct: 338 FLSDTPEALINAGDFHGLQVLVGVVKDEGSYFLVYGAPGFSKDNESLISRAEFLAGVRVG 397

Query: 350 EAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDFVYNHPSQRTITQL---LDENAGKI 406
             Q+   A      +  D  L  E  + L++  SD V +H     + QL   L     ++
Sbjct: 398 VPQVSDLAAEAVVLHYTD-WLHPEDPARLREALSDVVGDHNVVCPVAQLAGRLAAQGARV 456

Query: 407 YEYLFSY-----SGELEDGAEHSSELNYLFETAGGSDR--TEEEQLMVDRITTLWTNFVK 459
           Y Y+F +     S  L  G  H  E+ ++F       R  T EE++   R+   W NF +
Sbjct: 457 YAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLMRYWANFAR 516

Query: 460 FGNPTPKSTDLIPTIWEPVTADTRPVLVLD 489
            G+P        P  W P TA  +  + LD
Sbjct: 517 TGDPNEPRDPKAPQ-WPPYTAGAQQYVSLD 545


>AK090997-1|BAC03565.1|  469|Homo sapiens protein ( Homo sapiens
           cDNA FLJ33678 fis, clone BRAWH2002191, weakly similar to
           FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
           3.1.2.14). ).
          Length = 469

 Score =  151 bits (365), Expect = 8e-36
 Identities = 136/435 (31%), Positives = 206/435 (47%), Gaps = 39/435 (8%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRH-GVLVVTMNYRLGP 154
           +CL LNIY P+ A + + +PVLVW  GG F TGSAS +    +  +  VLVV + YRLG 
Sbjct: 14  DCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGI 73

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       A GN   +DQ  ALSW++ NI  FGG+P +VTI G+ AGA SV   + S 
Sbjct: 74  FGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSP 133

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVEAA--IKLAVHLGLNTTETEEAIQFLTKTSPDL 271
             K LFHK I+ESG      +  + D E +  +++  H   N     EA+    +T P  
Sbjct: 134 MAKGLFHKAIMESGVAIIPYLEAH-DYEKSEDLQVVAHFCGNNASDSEALLRCLRTKP-- 190

Query: 272 VVAAAKELELQLKPCRERSFSGISN--FVESDPYSLTNKKKVRNTPIMIGNTNKEKKSLS 329
               +KEL L L   + +SF+ + +  F  ++P  L ++K  +  P +IG  + E   L 
Sbjct: 191 ----SKEL-LTLSQ-KTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNSHECGFLL 244

Query: 330 ADYFSTDPFYEKLKS-NFNLDEAQIE---KAAKNVRHFYIGDSSLSAEVASELQDFESDF 385
               + +      KS   +L +  +    +    V + Y  D     E+   L D   D 
Sbjct: 245 PMKEAPEILSGSNKSLALHLIQNILHIPPQYLHLVANEYFHDKHSLTEIRDSLLDLLGDV 304

Query: 386 VYNHPSQRTITQLLDENAGKIYEYLFSYSGE-LED------GAEHSSELNYLFETA---G 435
            +  P+  T     D  A  +Y Y F +  +  ED       A+H+ E+ ++F  A   G
Sbjct: 305 FFVVPALITARYHRDAGA-PVYFYEFRHRPQCFEDTKPAFVKADHADEVRFVFGGAFLKG 363

Query: 436 G----SDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDKD 491
                   TEEE+L+  ++   W  F + GN  P   DL  ++W P    T   L LD +
Sbjct: 364 DIVMFEGATEEEKLLSRKMMKYWATFARTGN--PNGNDL--SLW-PAYNLTEQYLQLDLN 418

Query: 492 VRLDSRIERQRMAYW 506
           + L  R++  R+ +W
Sbjct: 419 MSLGQRLKEPRVEFW 433


>AB025027-1|BAB85656.1|  565|Homo sapiens brain carboxylesterase
           hBr2 protein.
          Length = 565

 Score =  149 bits (362), Expect = 2e-35
 Identities = 122/436 (27%), Positives = 195/436 (44%), Gaps = 30/436 (6%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  +  + +PV+VWIHGG    G AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGLALSAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF         GN G  DQ  AL W++ NIA+FGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHGRGNWGHLDQLAALRWVQENIANFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVV 273
             K LFH+ I ESG   +  +      + A ++AV  G  +T +   +  L + + D ++
Sbjct: 235 LAKNLFHRAISESGVALTAALVKKDMKDTAQQIAVFAGCKSTTSAVLVHCLRQKTEDELL 294

Query: 274 AAAKELE---LQLKPCRERSFSGISNFVE-----SDPYSLTNKKKVRNTPIMIGNTNKE- 324
             + +L+   L L      S+  +   V+       P  +  +KK  + P +IG   +E 
Sbjct: 295 EVSLKLKFFTLDLLGDPRESYPFLPTVVDGVLLPKMPQEILAEKKFNSVPYIIGINKQEF 354

Query: 325 --KKSLSADY-FSTDPFYEKLKSNFNLDEAQI----EKAAKNVRHFYIGDSSLSAEVASE 377
                +   Y  S D   +K  S+       I    E+        Y+G +    +  + 
Sbjct: 355 GWLLPMMMGYPLSEDKLDQKTASSLLWKSYPIANIPEELTPLASEKYLGGTDDPVKKKAL 414

Query: 378 LQDFESDFVYNHPSQRTITQLLDENAGK-IYEYLF--SYSGELEDG---AEHSSELNYLF 431
             D   D V+  PS        D  A   +YE+ +  S+S +++      +H  EL  +F
Sbjct: 415 FLDMLGDVVFGVPSVTVARHHRDAGAPTYMYEFQYHPSFSSDMKPQTVVGDHGDELFSVF 474

Query: 432 ETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDK 490
                     EE++ + + +  LW NF + GNP  K      + W P        L +  
Sbjct: 475 GAPFLKGGASEEEIRLSKMMMKLWANFARSGNPMGKGC----SSW-PAYDQKEGYLQIGI 529

Query: 491 DVRLDSRIERQRMAYW 506
             +   +++ + MA+W
Sbjct: 530 PTQPAQKLKSKEMAFW 545


>M32391-1|AAA99296.1|  602|Homo sapiens butyrylcholinesterase
           protein.
          Length = 602

 Score =  147 bits (356), Expect = 1e-34
 Identities = 156/553 (28%), Positives = 243/553 (43%), Gaps = 55/553 (9%)

Query: 3   FMPWFLLLMLSYVQANLVRVDPLVLISNQGLVRGHKAA--DGDYSIFLGIPYAKVDVNN- 59
           F+ WFLLL +   +++    D +++ +  G VRG       G  + FLGIPYA+  +   
Sbjct: 12  FLFWFLLLCMLIGKSHTE--DDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRL 69

Query: 60  PFSTATDPIAFPEIIHDAVDEVRCPQTSSSV-----GEQTLN--------CLRLNIYVPS 106
            F        + +I +       C Q          G +  N        CL LN+++P 
Sbjct: 70  RFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP- 128

Query: 107 AASSRNPMPVLVWIHGGDFATGSAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDV- 162
           A   +N   VL+WI+GG F TG++S   Y  K + R   V+VV+MNYR+G  GFL L   
Sbjct: 129 APKPKNAT-VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGN 187

Query: 163 PTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYS-DNEKLFHK 221
           P A GN GL DQ  AL W++ NIA+FGGNP +VT+ G+ AGA SV L L S  +  LF +
Sbjct: 188 PEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTR 247

Query: 222 VIIESGTPQSEGMFVNADVEA---AIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKE 278
            I++SG+  +    V +  EA    + LA   G +     E I+ L    P  ++     
Sbjct: 248 AILQSGSFNAP-WAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAF 306

Query: 279 LELQLKPCRERSFSGI-SNFVESDPYSLTNKKKVRNTPIMIGNTNKEKKSLSADY----F 333
           +     P        +  +F+   P  L    + + T I++G  NK++ +    Y    F
Sbjct: 307 VVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVG-VNKDEGTAFLVYGAPGF 365

Query: 334 STD--------PFYEKLKSNFNLDEAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDF 385
           S D         F E LK  F    ++  K +    +    D          L D   D+
Sbjct: 366 SKDNNSIITRKEFQEGLKIFFP-GVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDY 424

Query: 386 VYNHPSQRTITQLLDENAGKIYEYLFSY-SGELE----DGAEHSSELNYLF--ETAGGSD 438
            +  P+    T+   E     + Y F + S +L      G  H  E+ ++F        +
Sbjct: 425 NFICPALE-FTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDN 483

Query: 439 RTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSR 497
            T+ E+++   I   W NF K+GN  P  T    T W    +  +  L L+ +  R+ ++
Sbjct: 484 YTKAEEILSRSIVKRWANFAKYGN--PNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTK 541

Query: 498 IERQRMAYWDLFF 510
           +  Q+  +W  FF
Sbjct: 542 LRAQQCRFWTSFF 554


>M16541-1|AAA98113.1|  602|Homo sapiens BCHE protein.
          Length = 602

 Score =  147 bits (356), Expect = 1e-34
 Identities = 156/553 (28%), Positives = 243/553 (43%), Gaps = 55/553 (9%)

Query: 3   FMPWFLLLMLSYVQANLVRVDPLVLISNQGLVRGHKAA--DGDYSIFLGIPYAKVDVNN- 59
           F+ WFLLL +   +++    D +++ +  G VRG       G  + FLGIPYA+  +   
Sbjct: 12  FLFWFLLLCMLIGKSHTE--DDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRL 69

Query: 60  PFSTATDPIAFPEIIHDAVDEVRCPQTSSSV-----GEQTLN--------CLRLNIYVPS 106
            F        + +I +       C Q          G +  N        CL LN+++P 
Sbjct: 70  RFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP- 128

Query: 107 AASSRNPMPVLVWIHGGDFATGSAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDV- 162
           A   +N   VL+WI+GG F TG++S   Y  K + R   V+VV+MNYR+G  GFL L   
Sbjct: 129 APKPKNAT-VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGN 187

Query: 163 PTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYS-DNEKLFHK 221
           P A GN GL DQ  AL W++ NIA+FGGNP +VT+ G+ AGA SV L L S  +  LF +
Sbjct: 188 PEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTR 247

Query: 222 VIIESGTPQSEGMFVNADVEA---AIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKE 278
            I++SG+  +    V +  EA    + LA   G +     E I+ L    P  ++     
Sbjct: 248 AILQSGSFNAP-WAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAF 306

Query: 279 LELQLKPCRERSFSGI-SNFVESDPYSLTNKKKVRNTPIMIGNTNKEKKSLSADY----F 333
           +     P        +  +F+   P  L    + + T I++G  NK++ +    Y    F
Sbjct: 307 VVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVG-VNKDEGTAFLVYGAPGF 365

Query: 334 STD--------PFYEKLKSNFNLDEAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDF 385
           S D         F E LK  F    ++  K +    +    D          L D   D+
Sbjct: 366 SKDNNSIITRKEFQEGLKIFFP-GVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDY 424

Query: 386 VYNHPSQRTITQLLDENAGKIYEYLFSY-SGELE----DGAEHSSELNYLF--ETAGGSD 438
            +  P+    T+   E     + Y F + S +L      G  H  E+ ++F        +
Sbjct: 425 NFICPALE-FTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDN 483

Query: 439 RTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSR 497
            T+ E+++   I   W NF K+GN  P  T    T W    +  +  L L+ +  R+ ++
Sbjct: 484 YTKAEEILSRSIVKRWANFAKYGN--PNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTK 541

Query: 498 IERQRMAYWDLFF 510
           +  Q+  +W  FF
Sbjct: 542 LRAQQCRFWTSFF 554


>M16474-1|AAA52015.1|  602|Homo sapiens BCHE protein.
          Length = 602

 Score =  147 bits (356), Expect = 1e-34
 Identities = 156/553 (28%), Positives = 243/553 (43%), Gaps = 55/553 (9%)

Query: 3   FMPWFLLLMLSYVQANLVRVDPLVLISNQGLVRGHKAA--DGDYSIFLGIPYAKVDVNN- 59
           F+ WFLLL +   +++    D +++ +  G VRG       G  + FLGIPYA+  +   
Sbjct: 12  FLFWFLLLCMLIGKSHTE--DDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRL 69

Query: 60  PFSTATDPIAFPEIIHDAVDEVRCPQTSSSV-----GEQTLN--------CLRLNIYVPS 106
            F        + +I +       C Q          G +  N        CL LN+++P 
Sbjct: 70  RFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP- 128

Query: 107 AASSRNPMPVLVWIHGGDFATGSAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDV- 162
           A   +N   VL+WI+GG F TG++S   Y  K + R   V+VV+MNYR+G  GFL L   
Sbjct: 129 APKPKNAT-VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGN 187

Query: 163 PTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYS-DNEKLFHK 221
           P A GN GL DQ  AL W++ NIA+FGGNP +VT+ G+ AGA SV L L S  +  LF +
Sbjct: 188 PEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTR 247

Query: 222 VIIESGTPQSEGMFVNADVEA---AIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKE 278
            I++SG+  +    V +  EA    + LA   G +     E I+ L    P  ++     
Sbjct: 248 AILQSGSFNAP-WAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAF 306

Query: 279 LELQLKPCRERSFSGI-SNFVESDPYSLTNKKKVRNTPIMIGNTNKEKKSLSADY----F 333
           +     P        +  +F+   P  L    + + T I++G  NK++ +    Y    F
Sbjct: 307 VVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVG-VNKDEGTAFLVYGAPGF 365

Query: 334 STD--------PFYEKLKSNFNLDEAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDF 385
           S D         F E LK  F    ++  K +    +    D          L D   D+
Sbjct: 366 SKDNNSIITRKEFQEGLKIFFP-GVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDY 424

Query: 386 VYNHPSQRTITQLLDENAGKIYEYLFSY-SGELE----DGAEHSSELNYLF--ETAGGSD 438
            +  P+    T+   E     + Y F + S +L      G  H  E+ ++F        +
Sbjct: 425 NFICPALE-FTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDN 483

Query: 439 RTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSR 497
            T+ E+++   I   W NF K+GN  P  T    T W    +  +  L L+ +  R+ ++
Sbjct: 484 YTKAEEILSRSIVKRWANFAKYGN--PNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTK 541

Query: 498 IERQRMAYWDLFF 510
           +  Q+  +W  FF
Sbjct: 542 LRAQQCRFWTSFF 554


>BC018141-1|AAH18141.1|  602|Homo sapiens butyrylcholinesterase
           protein.
          Length = 602

 Score =  147 bits (356), Expect = 1e-34
 Identities = 156/553 (28%), Positives = 243/553 (43%), Gaps = 55/553 (9%)

Query: 3   FMPWFLLLMLSYVQANLVRVDPLVLISNQGLVRGHKAA--DGDYSIFLGIPYAKVDVNN- 59
           F+ WFLLL +   +++    D +++ +  G VRG       G  + FLGIPYA+  +   
Sbjct: 12  FLFWFLLLCMLIGKSHTE--DDIIIATKNGKVRGMNLTVFGGTVTAFLGIPYAQPPLGRL 69

Query: 60  PFSTATDPIAFPEIIHDAVDEVRCPQTSSSV-----GEQTLN--------CLRLNIYVPS 106
            F        + +I +       C Q          G +  N        CL LN+++P 
Sbjct: 70  RFKKPQSLTKWSDIWNATKYANSCCQNIDQSFPGFHGSEMWNPNTDLSEDCLYLNVWIP- 128

Query: 107 AASSRNPMPVLVWIHGGDFATGSAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDV- 162
           A   +N   VL+WI+GG F TG++S   Y  K + R   V+VV+MNYR+G  GFL L   
Sbjct: 129 APKPKNAT-VLIWIYGGGFQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGN 187

Query: 163 PTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYS-DNEKLFHK 221
           P A GN GL DQ  AL W++ NIA+FGGNP +VT+ G+ AGA SV L L S  +  LF +
Sbjct: 188 PEAPGNMGLFDQQLALQWVQKNIAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTR 247

Query: 222 VIIESGTPQSEGMFVNADVEA---AIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKE 278
            I++SG+  +    V +  EA    + LA   G +     E I+ L    P  ++     
Sbjct: 248 AILQSGSFNAP-WAVTSLYEARNRTLNLAKLTGCSRENETEIIKCLRNKDPQEILLNEAF 306

Query: 279 LELQLKPCRERSFSGI-SNFVESDPYSLTNKKKVRNTPIMIGNTNKEKKSLSADY----F 333
           +     P        +  +F+   P  L    + + T I++G  NK++ +    Y    F
Sbjct: 307 VVPYGTPLSVNFGPTVDGDFLTDMPDILLELGQFKKTQILVG-VNKDEGTAFLVYGAPGF 365

Query: 334 STD--------PFYEKLKSNFNLDEAQIEKAAKNVRHFYIGDSSLSAEVASELQDFESDF 385
           S D         F E LK  F    ++  K +    +    D          L D   D+
Sbjct: 366 SKDNNSIITRKEFQEGLKIFFP-GVSEFGKESILFHYTDWVDDQRPENYREALGDVVGDY 424

Query: 386 VYNHPSQRTITQLLDENAGKIYEYLFSY-SGELE----DGAEHSSELNYLF--ETAGGSD 438
            +  P+    T+   E     + Y F + S +L      G  H  E+ ++F        +
Sbjct: 425 NFICPALE-FTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVFGLPLERRDN 483

Query: 439 RTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSR 497
            T+ E+++   I   W NF K+GN  P  T    T W    +  +  L L+ +  R+ ++
Sbjct: 484 YTKAEEILSRSIVKRWANFAKYGN--PNETQNNSTSWPVFKSTEQKYLTLNTESTRIMTK 541

Query: 498 IERQRMAYWDLFF 510
           +  Q+  +W  FF
Sbjct: 542 LRAQQCRFWTSFF 554


>BC064573-1|AAH64573.1|  442|Homo sapiens FLJ37464 protein protein.
          Length = 442

 Score =  146 bits (354), Expect = 2e-34
 Identities = 125/434 (28%), Positives = 196/434 (45%), Gaps = 35/434 (8%)

Query: 101 NIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGPYGFLC 159
           N+Y P+ A     +PV+VW  GG F  G+AS Y G     R  V++V + +RLG +GFL 
Sbjct: 1   NVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGIFGFLS 60

Query: 160 LDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVL-LQLYSDNEKL 218
            D   A GN GL DQ  AL W++ NIA+FGG+P NVT+ GQ AGA S+  L +      L
Sbjct: 61  TDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGL 120

Query: 219 FHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKE 278
           FH+ I +SGT           ++ A K+A   G N   T+  +  L   S   V+  + +
Sbjct: 121 FHRAISQSGTALFRLFITRNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNK 180

Query: 279 LE-LQLKPCRER-----SFSGISN--FVESDPYSLTNKKKVRNTPIMIGNTNKE------ 324
           +  LQL   R+      S S + +   +  DP  L  + KV + P ++G  N E      
Sbjct: 181 MRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLP 240

Query: 325 ---KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKNVRHFYIGDSSLSAE-VASELQD 380
              K  L+      +   + L S   L     E+    V  +    +    + + + + D
Sbjct: 241 YIMKFPLNRQAMRKETITKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMD 300

Query: 381 FESDFVYNHPSQRTITQLLDENAGKIYEYLFSYSGE------LEDGAEHSSELNYLF--E 432
              D  + + + +T     D     +Y Y F +           DGA+H  E+ +LF   
Sbjct: 301 IVQDATFVYATLQTAHYHRDAGL-PVYLYEFEHHARGIIVKPRTDGADHGDEMYFLFGGP 359

Query: 433 TAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDKDV 492
            A G    +E+ L + ++   W NF + GNP   +   +P  W     D +  L LD   
Sbjct: 360 FATGLSMGKEKALSL-QMMKYWANFARTGNPNDGN---LP-CWPRYNKDEK-YLQLDFTT 413

Query: 493 RLDSRIERQRMAYW 506
           R+  +++ ++MA+W
Sbjct: 414 RVGMKLKEKKMAFW 427


>AB025028-1|BAA84996.1|  567|Homo sapiens brain carboxylesterase
           hBr3 protein.
          Length = 567

 Score =  142 bits (343), Expect = 4e-33
 Identities = 131/462 (28%), Positives = 206/462 (44%), Gaps = 44/462 (9%)

Query: 45  SIFLGIPYAKVDVNN----------PFSTATDPIAFPEII-HDAV-----DEVRCPQTSS 88
           + FLG+P+AK  + +          P+S   +  ++P +   DAV      E+   +  +
Sbjct: 48  AFFLGVPFAKPPLGSLRFAPPQPAEPWSFVKNTTSYPPMCSQDAVGWQVLSELFTNRKEN 107

Query: 89  SVGEQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVT 147
              + + +CL LNIY P+  +  + +PV+VWIHGG    G AS Y G+       V+VVT
Sbjct: 108 IPLQFSEDCLYLNIYTPADLTKNSRLPVMVWIHGGGLVVGGASTYDGLALSAHENVVVVT 167

Query: 148 MNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV 207
           + YRLG +GF       + GN G  DQ  AL W+++NIA+FGGNP +VTI G+ AG  SV
Sbjct: 168 IQYRLGIWGFFSTGDEHSRGNWGHLDQVAALRWVQDNIANFGGNPGSVTIFGESAGGFSV 227

Query: 208 LLQLYSDNEK-LFHKVIIESGTPQSEGMFVNADVEAAIKLAVHL-GLNTTETEEAIQFL- 264
            + + S   K LFH+ I ESG   +  + +  DV+    L   L G  TT +   +  L 
Sbjct: 228 SVLVLSPLAKNLFHRAISESGVSLTAAL-ITTDVKPIAGLVATLSGCKTTTSAVMVHCLR 286

Query: 265 TKTSPDLVVAAAK----ELELQLKPCRERSF--SGISNFV-ESDPYSLTNKKKVRNTPIM 317
            KT  +L+  + K    +L+L   P     F  + I   V    P  +  +K     P +
Sbjct: 287 QKTEDELLETSLKLNLFKLDLLGNPKESYPFLPTVIDGVVLPKAPEEILAEKSFSTVPYI 346

Query: 318 IGNTNKE----KKSLSADYFSTDPFYEKLKSNFNLDEAQIEKAAKN----VRHFYIGDSS 369
           +G   +E      +L     +     +K  ++         K ++N    V   Y+G + 
Sbjct: 347 VGINKQEFGWIIPTLMGYPLAEGKLDQKTANSLLWKSYPTLKISENMIPVVAEKYLGGTD 406

Query: 370 LSAEVASELQDFESDFVYNHPSQRTITQLLDENAGKI---YEYLFSYSGELEDG----AE 422
              +     QD  +D V+  PS        D  A      +EY  S+    ED      +
Sbjct: 407 DLTKKKDLFQDLMADVVFGVPSVIVSRSHRDAGASTYMYEFEYRPSFVSRHEDPKAVIGD 466

Query: 423 HSSELNYLFETAGGSDRTEEEQLMVDR-ITTLWTNFVKFGNP 463
           H  E+  +F +    D   EE+  + + +   W NF + GNP
Sbjct: 467 HGDEIFSVFGSPFLKDGASEEETNLSKMVMKFWANFARNGNP 508


>AB025026-1|BAA84995.1|  429|Homo sapiens brain carboxylesterase
           hBr1 protein.
          Length = 429

 Score =  140 bits (339), Expect = 1e-32
 Identities = 88/240 (36%), Positives = 125/240 (52%), Gaps = 11/240 (4%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 115 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 174

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G+ AG  SV + + S 
Sbjct: 175 WGFFSTGDEHSRGNWGHLDQVAALRWVQDNIASFGGNPGSVTIFGESAGGESVSVLVLSP 234

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVE-AAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             K LFH+ I ESG   +  +    DV+  A ++A+  G  TT +   +  L  KT  +L
Sbjct: 235 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEQIAITAGCKTTTSAVMVHCLRQKTEEEL 294

Query: 272 VVAAAK----ELELQLKPCRERSFSGI---SNFVESDPYSLTNKKKVRNTPIMIGNTNKE 324
           +    K     L+LQ  P   +   G       +   P  L  ++     P M+G   +E
Sbjct: 295 LETTLKMKFLSLDLQGDPRESQPLLGTVIDGMLLLKTPEELQAERNFHTVPYMVGINKQE 354


>Y09616-1|CAA70831.1|  559|Homo sapiens carboxylesterase protein.
          Length = 559

 Score =  136 bits (329), Expect = 2e-31
 Identities = 134/505 (26%), Positives = 219/505 (43%), Gaps = 51/505 (10%)

Query: 38  KAADGDYSIFLGIPYAKVDVNN-PFSTATDPIAFPEIIHDAVDEVRCPQTSSSVGEQTLN 96
           K A+     FLGIP+AK  +    F+    P ++  +         C Q  ++V  + L+
Sbjct: 49  KGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLS 108

Query: 97  --------------CLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRH 141
                         CL L+IY P+ +   + +PV+VWIHGG    G AS Y G       
Sbjct: 109 QFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE 168

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQD 201
            V+VV + YRLG  GF       A+GN G  DQ  AL W++ NIA FGGNP  VTI G+ 
Sbjct: 169 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 228

Query: 202 AGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFV-NADVEAAIKLAVHLGLNTTETEE 259
           AG TSV   + S  ++ LFH  I+ESG     G+   +ADV + + +A     +  ++E 
Sbjct: 229 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTV-VANLSACDQVDSEA 287

Query: 260 AIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIG 319
            +  L   S + ++A  K  ++           G+  F+   P  L      +  P ++G
Sbjct: 288 LVGCLRGKSKEEILAINKPFKM-----IPGVVDGV--FLPRHPQELLASADFQPVPSIVG 340

Query: 320 NTNKEKKSLSAD---YFSTDPFYEKLKSNFNLDEAQI-----EKAAKNVRHFYIGDSSLS 371
             N E   L       + T    ++  S   L +              +R  YIGD+   
Sbjct: 341 VNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDP 400

Query: 372 AEVASELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYSGE-LED------GAEHS 424
             + ++ Q+  +D ++  P+ +        +   +Y Y F +    L++       A+H 
Sbjct: 401 QTLQAQFQEMMADSMFVIPALQVAH--FQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHG 458

Query: 425 SELNYLFETAGGSDR---TEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTAD 481
            EL ++F +  G +    TEEE+ +  ++   W NF + GNP  +    +P  W P+   
Sbjct: 459 DELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEG---LPH-W-PLFDQ 513

Query: 482 TRPVLVLDKDVRLDSRIERQRMAYW 506
               L L+    +   ++  R+ +W
Sbjct: 514 EEQYLQLNLQPAVGRALKAHRLQFW 538


>U60553-1|AAB03611.1|  550|Homo sapiens carboxylesterase protein.
          Length = 550

 Score =  136 bits (329), Expect = 2e-31
 Identities = 134/505 (26%), Positives = 219/505 (43%), Gaps = 51/505 (10%)

Query: 38  KAADGDYSIFLGIPYAKVDVNN-PFSTATDPIAFPEIIHDAVDEVRCPQTSSSVGEQTLN 96
           K A+     FLGIP+AK  +    F+    P ++  +         C Q  ++V  + L+
Sbjct: 40  KGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLS 99

Query: 97  --------------CLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRH 141
                         CL L+IY P+ +   + +PV+VWIHGG    G AS Y G       
Sbjct: 100 QFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE 159

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQD 201
            V+VV + YRLG  GF       A+GN G  DQ  AL W++ NIA FGGNP  VTI G+ 
Sbjct: 160 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 219

Query: 202 AGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFV-NADVEAAIKLAVHLGLNTTETEE 259
           AG TSV   + S  ++ LFH  I+ESG     G+   +ADV + + +A     +  ++E 
Sbjct: 220 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTV-VANLSACDQVDSEA 278

Query: 260 AIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIG 319
            +  L   S + ++A  K  ++           G+  F+   P  L      +  P ++G
Sbjct: 279 LVGCLRGKSKEEILAINKPFKM-----IPGVVDGV--FLPRHPQELLASADFQPVPSIVG 331

Query: 320 NTNKEKKSLSAD---YFSTDPFYEKLKSNFNLDEAQI-----EKAAKNVRHFYIGDSSLS 371
             N E   L       + T    ++  S   L +              +R  YIGD+   
Sbjct: 332 VNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDP 391

Query: 372 AEVASELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYSGE-LED------GAEHS 424
             + ++ Q+  +D ++  P+ +        +   +Y Y F +    L++       A+H 
Sbjct: 392 QTLQAQFQEMMADSMFVIPALQVAH--FQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHG 449

Query: 425 SELNYLFETAGGSDR---TEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTAD 481
            EL ++F +  G +    TEEE+ +  ++   W NF + GNP  +    +P  W P+   
Sbjct: 450 DELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEG---LPH-W-PLFDQ 504

Query: 482 TRPVLVLDKDVRLDSRIERQRMAYW 506
               L L+    +   ++  R+ +W
Sbjct: 505 EEQYLQLNLQPAVGRALKAHRLQFW 529


>D50579-1|BAA23606.1|  559|Homo sapiens carboxylesterase precursor
           protein.
          Length = 559

 Score =  136 bits (329), Expect = 2e-31
 Identities = 134/505 (26%), Positives = 219/505 (43%), Gaps = 51/505 (10%)

Query: 38  KAADGDYSIFLGIPYAKVDVNN-PFSTATDPIAFPEIIHDAVDEVRCPQTSSSVGEQTLN 96
           K A+     FLGIP+AK  +    F+    P ++  +         C Q  ++V  + L+
Sbjct: 49  KGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLS 108

Query: 97  --------------CLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRH 141
                         CL L+IY P+ +   + +PV+VWIHGG    G AS Y G       
Sbjct: 109 QFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE 168

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQD 201
            V+VV + YRLG  GF       A+GN G  DQ  AL W++ NIA FGGNP  VTI G+ 
Sbjct: 169 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 228

Query: 202 AGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFV-NADVEAAIKLAVHLGLNTTETEE 259
           AG TSV   + S  ++ LFH  I+ESG     G+   +ADV + + +A     +  ++E 
Sbjct: 229 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTV-VANLSACDQVDSEA 287

Query: 260 AIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIG 319
            +  L   S + ++A  K  ++           G+  F+   P  L      +  P ++G
Sbjct: 288 LVGCLRGKSKEEILAINKPFKM-----IPGVVDGV--FLPRHPQELLASADFQPVPSIVG 340

Query: 320 NTNKEKKSLSAD---YFSTDPFYEKLKSNFNLDEAQI-----EKAAKNVRHFYIGDSSLS 371
             N E   L       + T    ++  S   L +              +R  YIGD+   
Sbjct: 341 VNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDP 400

Query: 372 AEVASELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYSGE-LED------GAEHS 424
             + ++ Q+  +D ++  P+ +        +   +Y Y F +    L++       A+H 
Sbjct: 401 QTLQAQFQEMMADSMFVIPALQVAH--FQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHG 458

Query: 425 SELNYLFETAGGSDR---TEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTAD 481
            EL ++F +  G +    TEEE+ +  ++   W NF + GNP  +    +P  W P+   
Sbjct: 459 DELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEG---LPH-W-PLFDQ 513

Query: 482 TRPVLVLDKDVRLDSRIERQRMAYW 506
               L L+    +   ++  R+ +W
Sbjct: 514 EEQYLQLNLQPAVGRALKAHRLQFW 538


>BC032095-1|AAH32095.1|  623|Homo sapiens carboxylesterase 2
           (intestine, liver) protein.
          Length = 623

 Score =  136 bits (329), Expect = 2e-31
 Identities = 134/505 (26%), Positives = 219/505 (43%), Gaps = 51/505 (10%)

Query: 38  KAADGDYSIFLGIPYAKVDVNN-PFSTATDPIAFPEIIHDAVDEVRCPQTSSSVGEQTLN 96
           K A+     FLGIP+AK  +    F+    P ++  +         C Q  ++V  + L+
Sbjct: 113 KGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLS 172

Query: 97  --------------CLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRH 141
                         CL L+IY P+ +   + +PV+VWIHGG    G AS Y G       
Sbjct: 173 QFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE 232

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQD 201
            V+VV + YRLG  GF       A+GN G  DQ  AL W++ NIA FGGNP  VTI G+ 
Sbjct: 233 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 292

Query: 202 AGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFV-NADVEAAIKLAVHLGLNTTETEE 259
           AG TSV   + S  ++ LFH  I+ESG     G+   +ADV + + +A     +  ++E 
Sbjct: 293 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTV-VANLSACDQVDSEA 351

Query: 260 AIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIG 319
            +  L   S + ++A  K  ++           G+  F+   P  L      +  P ++G
Sbjct: 352 LVGCLRGKSKEEILAINKPFKM-----IPGVVDGV--FLPRHPQELLASADFQPVPSIVG 404

Query: 320 NTNKEKKSLSAD---YFSTDPFYEKLKSNFNLDEAQI-----EKAAKNVRHFYIGDSSLS 371
             N E   L       + T    ++  S   L +              +R  YIGD+   
Sbjct: 405 VNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDP 464

Query: 372 AEVASELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYSGE-LED------GAEHS 424
             + ++ Q+  +D ++  P+ +        +   +Y Y F +    L++       A+H 
Sbjct: 465 QTLQAQFQEMMADSMFVIPALQVAH--FQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHG 522

Query: 425 SELNYLFETAGGSDR---TEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTAD 481
            EL ++F +  G +    TEEE+ +  ++   W NF + GNP  +    +P  W P+   
Sbjct: 523 DELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEG---LPH-W-PLFDQ 577

Query: 482 TRPVLVLDKDVRLDSRIERQRMAYW 506
               L L+    +   ++  R+ +W
Sbjct: 578 EEQYLQLNLQPAVGRALKAHRLQFW 602


>AY851164-1|AAW29943.1|  623|Homo sapiens carboxylesterase 2
           (intestine, liver) protein.
          Length = 623

 Score =  136 bits (329), Expect = 2e-31
 Identities = 134/505 (26%), Positives = 219/505 (43%), Gaps = 51/505 (10%)

Query: 38  KAADGDYSIFLGIPYAKVDVNN-PFSTATDPIAFPEIIHDAVDEVRCPQTSSSVGEQTLN 96
           K A+     FLGIP+AK  +    F+    P ++  +         C Q  ++V  + L+
Sbjct: 113 KGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLS 172

Query: 97  --------------CLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRH 141
                         CL L+IY P+ +   + +PV+VWIHGG    G AS Y G       
Sbjct: 173 QFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE 232

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQD 201
            V+VV + YRLG  GF       A+GN G  DQ  AL W++ NIA FGGNP  VTI G+ 
Sbjct: 233 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 292

Query: 202 AGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFV-NADVEAAIKLAVHLGLNTTETEE 259
           AG TSV   + S  ++ LFH  I+ESG     G+   +ADV + + +A     +  ++E 
Sbjct: 293 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTV-VANLSACDQVDSEA 351

Query: 260 AIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIG 319
            +  L   S + ++A  K  ++           G+  F+   P  L      +  P ++G
Sbjct: 352 LVGCLRGKSKEEILAINKPFKM-----IPGVVDGV--FLPRHPQELLASADFQPVPSIVG 404

Query: 320 NTNKEKKSLSAD---YFSTDPFYEKLKSNFNLDEAQI-----EKAAKNVRHFYIGDSSLS 371
             N E   L       + T    ++  S   L +              +R  YIGD+   
Sbjct: 405 VNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDP 464

Query: 372 AEVASELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYSGE-LED------GAEHS 424
             + ++ Q+  +D ++  P+ +        +   +Y Y F +    L++       A+H 
Sbjct: 465 QTLQAQFQEMMADSMFVIPALQVAH--FQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHG 522

Query: 425 SELNYLFETAGGSDR---TEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTAD 481
            EL ++F +  G +    TEEE+ +  ++   W NF + GNP  +    +P  W P+   
Sbjct: 523 DELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEG---LPH-W-PLFDQ 577

Query: 482 TRPVLVLDKDVRLDSRIERQRMAYW 506
               L L+    +   ++  R+ +W
Sbjct: 578 EEQYLQLNLQPAVGRALKAHRLQFW 602


>AK222724-1|BAD96444.1|  582|Homo sapiens carboxylesterase 2 isoform
           1 variant protein.
          Length = 582

 Score =  136 bits (328), Expect = 2e-31
 Identities = 134/505 (26%), Positives = 219/505 (43%), Gaps = 51/505 (10%)

Query: 38  KAADGDYSIFLGIPYAKVDVNN-PFSTATDPIAFPEIIHDAVDEVRCPQTSSSVGEQTLN 96
           K A+     FLGIP+AK  +    F+    P ++  +         C Q  ++V  + L+
Sbjct: 72  KGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLS 131

Query: 97  --------------CLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRH 141
                         CL L+IY P+ +   + +PV+VWIHGG    G AS Y G       
Sbjct: 132 QFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE 191

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQD 201
            V+VV + YRLG  GF       A+GN G  DQ  AL W++ NIA FGGNP  VTI G+ 
Sbjct: 192 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 251

Query: 202 AGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFV-NADVEAAIKLAVHLGLNTTETEE 259
           AG TSV   + S  ++ LFH  I+ESG     G+   +ADV + + +A     +  ++E 
Sbjct: 252 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTV-VANLSACDQVDSEA 310

Query: 260 AIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIG 319
            +  L   S + ++A  K  ++           G+  F+   P  L      +  P ++G
Sbjct: 311 LVGCLRGKSKEEILAINKPFKM-----IPGVVDGV--FLPRHPKELLASADFQPVPSIVG 363

Query: 320 NTNKEKKSLSAD---YFSTDPFYEKLKSNFNLDEAQI-----EKAAKNVRHFYIGDSSLS 371
             N E   L       + T    ++  S   L +              +R  YIGD+   
Sbjct: 364 VNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDP 423

Query: 372 AEVASELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYSGE-LED------GAEHS 424
             + ++ Q+  +D ++  P+ +        +   +Y Y F +    L++       A+H 
Sbjct: 424 QTLQAQFQEMMADSMFVIPALQVAH--FQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHG 481

Query: 425 SELNYLFETAGGSDR---TEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTAD 481
            EL ++F +  G +    TEEE+ +  ++   W NF + GNP  +    +P  W P+   
Sbjct: 482 DELPFVFRSFFGGNYIKFTEEEEQLSRKMMKYWANFARNGNPNGEG---LPH-W-PLFDQ 536

Query: 482 TRPVLVLDKDVRLDSRIERQRMAYW 506
               L L+    +   ++  R+ +W
Sbjct: 537 EEQYLQLNLQPAVGRALKAHRLQFW 561


>BC084555-1|AAH84555.1|  454|Homo sapiens FLJ37464 protein protein.
          Length = 454

 Score =  135 bits (327), Expect = 3e-31
 Identities = 87/239 (36%), Positives = 125/239 (52%), Gaps = 10/239 (4%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LN+Y P+ A     +PV+VW  GG F  G+AS Y G     R  V++V + +RLG 
Sbjct: 78  DCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGI 137

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVL-LQLYS 213
           +GFL  D   A GN GL DQ  AL W++ NIA+FGG+P NVT+ GQ AGA S+  L +  
Sbjct: 138 FGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSP 197

Query: 214 DNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVV 273
               LFH+ I +SGT        +  ++ A K+A   G N   T+  +  L   S   V+
Sbjct: 198 LASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVM 257

Query: 274 AAAKELE-LQLKPCRER-----SFSGISN--FVESDPYSLTNKKKVRNTPIMIGNTNKE 324
             + ++  LQL   R+      S S + +   +  DP  L  + KV + P ++G  N E
Sbjct: 258 RVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLE 316


>AY358504-1|AAQ88868.1|  545|Homo sapiens carboxylesterase Hlo
           protein.
          Length = 545

 Score =  135 bits (327), Expect = 3e-31
 Identities = 87/239 (36%), Positives = 125/239 (52%), Gaps = 10/239 (4%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LN+Y P+ A     +PV+VW  GG F  G+AS Y G     R  V++V + +RLG 
Sbjct: 219 DCLYLNVYAPARAPGDPQLPVMVWFPGGAFIVGAASSYEGSDLAAREKVVLVFLQHRLGI 278

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVL-LQLYS 213
           +GFL  D   A GN GL DQ  AL W++ NIA+FGG+P NVT+ GQ AGA S+  L +  
Sbjct: 279 FGFLSTDDSHARGNWGLLDQMAALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSP 338

Query: 214 DNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVV 273
               LFH+ I +SGT        +  ++ A K+A   G N   T+  +  L   S   V+
Sbjct: 339 LASGLFHRAISQSGTALFRLFITSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVM 398

Query: 274 AAAKELE-LQLKPCRER-----SFSGISN--FVESDPYSLTNKKKVRNTPIMIGNTNKE 324
             + ++  LQL   R+      S S + +   +  DP  L  + KV + P ++G  N E
Sbjct: 399 RVSNKMRFLQLNFQRDPEEIIWSMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLE 457


>BC053670-1|AAH53670.1|  568|Homo sapiens CES3 protein protein.
          Length = 568

 Score =  135 bits (326), Expect = 4e-31
 Identities = 127/469 (27%), Positives = 217/469 (46%), Gaps = 44/469 (9%)

Query: 36  GHKAADGDYSIFLGIPYAKVDVNNPFSTATDPIAFPEIIHDA-------VDEVRCPQTSS 88
           G K  D   ++FLGIP+A+  +     +A  P    E + DA       + +V    +S 
Sbjct: 49  GVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSR 108

Query: 89  SV--GEQTL-----NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRH 141
            V  G+Q +     +CL LN+Y P+   + +  PV+VW+HGG   TG+A+ Y    +  +
Sbjct: 109 FVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAY 168

Query: 142 G-VLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQ 200
           G V+VVT+ YRLG  GF       A GNQG  D   AL W++ NIA FGG+   VT+ G 
Sbjct: 169 GDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGG 228

Query: 201 DAGATSVL-LQLYSDNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEE 259
            AG + +  L L      LFH+ I +SG   + G+  +     A K+A  L  +++   E
Sbjct: 229 SAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAE 288

Query: 260 AIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIG 319
            +Q L +   + +V  +K+L+  + P    +  G + F +S P  L  +K   + P ++G
Sbjct: 289 MVQCLQQKEGEELV-LSKKLKNTIYPL---TVDG-TVFPKS-PKELLKEKPFHSVPFLMG 342

Query: 320 NTNKEKKSLSADYFSTDPFYEKLK-------SNFNLDEAQI-EKAAKNVRHFYIGDSSLS 371
             N E   L    +      E++        S   L    +  +    V   Y+G +S +
Sbjct: 343 VNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDA 402

Query: 372 AEVASELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYS----GELEDG---AEHS 424
                  Q+F  D   N P+  + ++ L ++   ++ Y F +      +++     A+H 
Sbjct: 403 QAKCQAFQEFMGDVFINVPTV-SFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHG 461

Query: 425 SELNYLF------ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKS 467
           +E  ++F      + +   + TEEE+ +   +   WT+F + G+P  K+
Sbjct: 462 AEGAFVFGGPFLMDESSRLEATEEEKQLSLTMMAQWTHFARTGDPNSKA 510


>BC028738-1|AAH28738.1|  518|Homo sapiens NLGN3 protein protein.
          Length = 518

 Score =  131 bits (317), Expect = 5e-30
 Identities = 92/269 (34%), Positives = 137/269 (50%), Gaps = 23/269 (8%)

Query: 67  PIAFPEIIHDAVDEVRCPQ--------TSSSVGEQTLNCLRLNIYVPSAASSRNP--MPV 116
           P   P+ IH AV EV  P          ++ + E   +CL LN+YVP+    R+    PV
Sbjct: 103 PPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDDIRDSGAKPV 162

Query: 117 LVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQY 175
           +V+IHGG +  G+ +      +  +G V+V+T+NYR+G  GFL      A GN GL DQ 
Sbjct: 163 MVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLDQI 222

Query: 176 KALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLYSDNEKLFHKVIIESGTPQSEGM 234
           +AL W+  NIA FGG+P  +T+ G   GA+ V LL L   +E LF + II+SG+  S   
Sbjct: 223 QALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSSWA 282

Query: 235 FVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKEL-ELQLKPCRER-SFS 292
                V+    LA  +G N  +T + +  L + S       AKEL E  ++P R   +F 
Sbjct: 283 VNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKS-------AKELVEQDIQPARYHVAFG 335

Query: 293 GI--SNFVESDPYSLTNKKKVRNTPIMIG 319
            +   + +  DP  L  + +  N  +M+G
Sbjct: 336 PVIDGDVIPDDPEILMEQGEFLNYDVMLG 364


>AY358609-1|AAQ88972.1|  571|Homo sapiens carboxylesterase Hlo
           protein.
          Length = 571

 Score =  131 bits (316), Expect = 7e-30
 Identities = 127/472 (26%), Positives = 215/472 (45%), Gaps = 47/472 (9%)

Query: 36  GHKAADGDYSIFLGIPYAKVDVNNPFSTATDPIAFPEIIHDA-------VDEVRCPQTSS 88
           G K  D   ++FLGIP+A+  +     +A  P    E + DA       + +V    +S 
Sbjct: 49  GVKGTDRLVNVFLGIPFAQPPLGPDRFSAPHPAQPWEGVRDASTAPPMCLQDVESMNSSR 108

Query: 89  SV--GEQTL-----NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRH 141
            V  G+Q +     +CL LN+Y P+   + +  PV+VW+HGG   TG+A+ Y    +  +
Sbjct: 109 FVLNGKQQIFSVSEDCLVLNVYSPAEVPAGSGRPVMVWVHGGALITGAATSYDGSALAAY 168

Query: 142 G-VLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQ 200
           G V+VVT+ YRLG  GF       A GNQG  D   AL W++ NIA FGG+   VT+ G 
Sbjct: 169 GDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVVAALRWVQENIAPFGGDLNCVTVFGG 228

Query: 201 DAGATSVL-LQLYSDNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEE 259
            AG + +  L L      LFH+ I +SG   + G+  +     A K+A  L  +++   E
Sbjct: 229 SAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGIIDSHPWPLAQKIANTLACSSSSPAE 288

Query: 260 AIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIG 319
            +Q L +   + +V  +K+L+  + P    +  G + F +S P  L  +K   + P ++G
Sbjct: 289 MVQCLQQKEGEELV-LSKKLKNTIYPL---TVDG-TVFPKS-PKELLKEKPFHSVPFLMG 342

Query: 320 NTNKEKKSLSADYFSTDPFYEKLK-------SNFNLDEAQI-EKAAKNVRHFYIGDSSLS 371
             N E   L    +      E++        S   L    +  +    V   Y+G +S +
Sbjct: 343 VNNHEFSWLIPRGWGLLDTMEQMSREDMLAISTPVLTSLDVPPEMMPTVIDEYLGSNSDA 402

Query: 372 AEVASELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYS----GELEDG---AEHS 424
                  Q+F  D   N P+  + ++ L ++   ++ Y F +      +++     A+H 
Sbjct: 403 QAKCQAFQEFMGDVFINVPTV-SFSRYLRDSGSPVFFYEFQHRPSSFAKIKPAWVKADHG 461

Query: 425 SELNYLF---------ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKS 467
           +E  ++F               + TEEE+ +   +   WT+F + G+P  K+
Sbjct: 462 AEGAFVFGGPFLMDESSRLAFPEATEEEKQLSLTMMAQWTHFARTGDPNSKA 513


>BC069548-1|AAH69548.1|  525|Homo sapiens carboxylesterase 7
           protein.
          Length = 525

 Score =  130 bits (315), Expect = 9e-30
 Identities = 89/235 (37%), Positives = 127/235 (54%), Gaps = 15/235 (6%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRH-GVLVVTMNYRLGP 154
           +CL LNIY P+ A + + +PVLVW  GG F TGSAS +    +  +  VLVV + YRLG 
Sbjct: 120 DCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGI 179

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       A GN   +DQ  ALSW++ NI  FGG+P +VTI G+ AGA SV   + S 
Sbjct: 180 FGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSP 239

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVEAA--IKLAVHLGLNTTETEEAIQFLTKTSPDL 271
             K LFHK I+ESG      +  + D E +  +++  H   N     EA+    +T P  
Sbjct: 240 MAKGLFHKAIMESGVAIIPYLEAH-DYEKSEDLQVVAHFCGNNASDSEALLRCLRTKP-- 296

Query: 272 VVAAAKELELQLKPCRERSFSGISN--FVESDPYSLTNKKKVRNTPIMIGNTNKE 324
               +KEL L L   + +SF+ + +  F  ++P  L ++K  +  P +IG  N E
Sbjct: 297 ----SKEL-LTLSQ-KTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE 345



 Score = 39.1 bits (87), Expect = 0.038
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 5/67 (7%)

Query: 440 TEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDKDVRLDSRIE 499
           TEEE+L+  ++   W  F + GN  P   DL  ++W P    T   L LD ++ L  R++
Sbjct: 428 TEEEKLLSRKMMKYWATFARTGN--PNGNDL--SLW-PAYNLTEQYLQLDLNMSLGQRLK 482

Query: 500 RQRMAYW 506
             R+ +W
Sbjct: 483 EPRVDFW 489


>AK056109-1|BAB71094.1|  525|Homo sapiens protein ( Homo sapiens
           cDNA FLJ31547 fis, clone NT2RI2001010, weakly similar to
           FATTY ACYL-COA HYDROLASE PRECURSOR, MEDIUM CHAIN (EC
           3.1.2.14). ).
          Length = 525

 Score =  130 bits (315), Expect = 9e-30
 Identities = 89/235 (37%), Positives = 127/235 (54%), Gaps = 15/235 (6%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRH-GVLVVTMNYRLGP 154
           +CL LNIY P+ A + + +PVLVW  GG F TGSAS +    +  +  VLVV + YRLG 
Sbjct: 120 DCLYLNIYAPAHADTGSKLPVLVWFPGGAFKTGSASIFDGSALAAYEDVLVVVVQYRLGI 179

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       A GN   +DQ  ALSW++ NI  FGG+P +VTI G+ AGA SV   + S 
Sbjct: 180 FGFFTTWDQHAPGNWAFKDQVAALSWVQKNIEFFGGDPSSVTIFGESAGAISVSSLILSP 239

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVEAA--IKLAVHLGLNTTETEEAIQFLTKTSPDL 271
             K LFHK I+ESG      +  + D E +  +++  H   N     EA+    +T P  
Sbjct: 240 MAKGLFHKAIMESGVAIIPYLEAH-DYEKSEDLQVVAHFCGNNASDSEALLRCLRTKP-- 296

Query: 272 VVAAAKELELQLKPCRERSFSGISN--FVESDPYSLTNKKKVRNTPIMIGNTNKE 324
               +KEL L L   + +SF+ + +  F  ++P  L ++K  +  P +IG  N E
Sbjct: 297 ----SKEL-LTLSQ-KTKSFTRVVDGAFFPNEPLDLLSQKAFKAIPSIIGVNNHE 345



 Score = 39.1 bits (87), Expect = 0.038
 Identities = 22/67 (32%), Positives = 35/67 (52%), Gaps = 5/67 (7%)

Query: 440 TEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDKDVRLDSRIE 499
           TEEE+L+  ++   W  F + GN  P   DL  ++W P    T   L LD ++ L  R++
Sbjct: 428 TEEEKLLSRKMMKYWATFARTGN--PNGNDL--SLW-PAYNLTEQYLQLDLNMSLGQRLK 482

Query: 500 RQRMAYW 506
             R+ +W
Sbjct: 483 EPRVDFW 489


>AF106005-1|AAF14185.1|  288|Homo sapiens carboxylesterase-related
           protein protein.
          Length = 288

 Score =  128 bits (310), Expect = 4e-29
 Identities = 68/157 (43%), Positives = 93/157 (59%), Gaps = 2/157 (1%)

Query: 96  NCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGP 154
           +CL LNIY P+  + +N +PV+VWIHGG    G+AS Y G+       V+VVT+ YRLG 
Sbjct: 117 DCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGI 176

Query: 155 YGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSD 214
           +GF       + GN G  DQ  AL W+++NIASFGGNP +VTI G  AG  SV + + S 
Sbjct: 177 WGFFSTGDEHSPGNWGHLDQLAALHWVQDNIASFGGNPGSVTIFGGSAGGESVSVLVLSP 236

Query: 215 NEK-LFHKVIIESGTPQSEGMFVNADVEAAIKLAVHL 250
             K LFH+ I ESG   +  +    DV+   ++ + L
Sbjct: 237 LAKNLFHRAISESGVALTSVLVKKGDVKPLAEVGLRL 273


>BC098417-1|AAH98417.1|  587|Homo sapiens CES2 protein protein.
          Length = 587

 Score =  127 bits (307), Expect = 8e-29
 Identities = 129/495 (26%), Positives = 206/495 (41%), Gaps = 47/495 (9%)

Query: 38  KAADGDYSIFLGIPYAKVDVNN-PFSTATDPIAFPEIIHDAVDEVRCPQTSSSVGEQTLN 96
           K A+     FLGIP+AK  +    F+    P ++  +         C Q  ++V  + L+
Sbjct: 93  KGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLS 152

Query: 97  --------------CLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRH 141
                         CL L+IY P+ +   + +PV+VWIHGG    G AS Y G       
Sbjct: 153 QFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE 212

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQD 201
            V+VV + YRLG  GF       A+GN G  DQ  AL W++ NIA FGGNP  VTI G+ 
Sbjct: 213 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 272

Query: 202 AGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFV-NADVEAAIKLAVHLGLNTTETEE 259
           AG TSV   + S  ++ LFH  I+ESG     G+   +ADV + + +A     +  ++E 
Sbjct: 273 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTV-VANLSACDQVDSEA 331

Query: 260 AIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIG 319
            +  L   S + ++A  K  ++           G+  F+   P  L      +  P ++G
Sbjct: 332 LVGCLRGKSKEEILAINKPFKM-----IPGVVDGV--FLPRHPQELLASADFQPVPSIVG 384

Query: 320 NTNKEKKSLSAD---YFSTDPFYEKLKSNFNLDEAQI-----EKAAKNVRHFYIGDSSLS 371
             N E   L       + T    ++  S   L +              +R  YIGD+   
Sbjct: 385 VNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDP 444

Query: 372 AEVASELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYSGELEDGAEHSSELNYLF 431
             + ++ Q+  +D ++  P+ +             YE+    S        H    +  F
Sbjct: 445 QTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHVKF 504

Query: 432 ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDKD 491
                   TEEE+ +  ++   W NF + GNP  +    +P  W P+       L L+  
Sbjct: 505 --------TEEEEQLSRKMMKYWANFARNGNPNGEG---LPH-W-PLFDQEEQYLQLNLQ 551

Query: 492 VRLDSRIERQRMAYW 506
             +   ++  R+ +W
Sbjct: 552 PAVGRALKAHRLQFW 566


>BC071874-1|AAH71874.1|  586|Homo sapiens CES2 protein protein.
          Length = 586

 Score =  127 bits (307), Expect = 8e-29
 Identities = 129/495 (26%), Positives = 206/495 (41%), Gaps = 47/495 (9%)

Query: 38  KAADGDYSIFLGIPYAKVDVNN-PFSTATDPIAFPEIIHDAVDEVRCPQTSSSVGEQTLN 96
           K A+     FLGIP+AK  +    F+    P ++  +         C Q  ++V  + L+
Sbjct: 92  KGANAGVQTFLGIPFAKPPLGPLRFAPPEPPESWSGVRDGTTHPAMCLQDLTAVESEFLS 151

Query: 97  --------------CLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDY-GVKNIVRH 141
                         CL L+IY P+ +   + +PV+VWIHGG    G AS Y G       
Sbjct: 152 QFNMTFPSDSMSEDCLYLSIYTPAHSHEGSNLPVMVWIHGGALVFGMASLYDGSMLAALE 211

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQD 201
            V+VV + YRLG  GF       A+GN G  DQ  AL W++ NIA FGGNP  VTI G+ 
Sbjct: 212 NVVVVIIQYRLGVLGFFSTGDKHATGNWGYLDQVAALRWVQQNIAHFGGNPDRVTIFGES 271

Query: 202 AGATSVLLQLYSD-NEKLFHKVIIESGTPQSEGMFV-NADVEAAIKLAVHLGLNTTETEE 259
           AG TSV   + S  ++ LFH  I+ESG     G+   +ADV + + +A     +  ++E 
Sbjct: 272 AGGTSVSSLVVSPISQGLFHGAIMESGVALLPGLIASSADVISTV-VANLSACDQVDSEA 330

Query: 260 AIQFLTKTSPDLVVAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIG 319
            +  L   S + ++A  K  ++           G+  F+   P  L      +  P ++G
Sbjct: 331 LVGCLRGKSKEEILAINKPFKM-----IPGVVDGV--FLPRHPQELLASADFQPVPSIVG 383

Query: 320 NTNKEKKSLSAD---YFSTDPFYEKLKSNFNLDEAQI-----EKAAKNVRHFYIGDSSLS 371
             N E   L       + T    ++  S   L +              +R  YIGD+   
Sbjct: 384 VNNNEFGWLIPKVMRIYDTQKEMDREASQAALQKMLTLLMLPPTFGDLLREEYIGDNGDP 443

Query: 372 AEVASELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYSGELEDGAEHSSELNYLF 431
             + ++ Q+  +D ++  P+ +             YE+    S        H    +  F
Sbjct: 444 QTLQAQFQEMMADSMFVIPALQVAHFQCSRAPVYFYEFQHQPSWLKNIRPPHMKADHVKF 503

Query: 432 ETAGGSDRTEEEQLMVDRITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDKD 491
                   TEEE+ +  ++   W NF + GNP  +    +P  W P+       L L+  
Sbjct: 504 --------TEEEEQLSRKMMKYWANFARNGNPNGEG---LPH-W-PLFDQEEQYLQLNLQ 550

Query: 492 VRLDSRIERQRMAYW 506
             +   ++  R+ +W
Sbjct: 551 PAVGRALKAHRLQFW 565


>BC032555-1|AAH32555.1|  823|Homo sapiens neuroligin 1 protein.
          Length = 823

 Score =  126 bits (304), Expect = 2e-28
 Identities = 114/344 (33%), Positives = 163/344 (47%), Gaps = 54/344 (15%)

Query: 22  VDPLVLISNQGLVRGHKAADGDYSI-----FLGIPYAKVDVN----------NPFS---- 62
           VDPLV  +N G +RG K    +  +     FLG+PYA               +P+S    
Sbjct: 51  VDPLVA-TNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRN 109

Query: 63  -TATDPIAFPEIIHDAVDEVRCPQ--------TSSSVGEQTLNCLRLNIYVPSAASSRN- 112
            T   P+    II   + EV  P          SS V +Q+ +CL LNIYVP+    R+ 
Sbjct: 110 ATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDS 169

Query: 113 --PMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYGFLCLDVPTASGNQ 169
             P PV+V+IHGG +  G+ + Y    +  +G V+V+T+NYRLG  GFL      A GN 
Sbjct: 170 GGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNY 229

Query: 170 GLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQL--YSDNEK-------LF 219
           GL D  +AL W   NI  FGG+P  +T+ G  AG + V LL L  YS+  +       LF
Sbjct: 230 GLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLF 289

Query: 220 HKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKEL 279
            + I +SGT  S         + A  LA  +G N ++T E ++ L K          KEL
Sbjct: 290 QRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQK-------KPYKEL 342

Query: 280 -ELQLKPCRER-SFSGI--SNFVESDPYSLTNKKKVRNTPIMIG 319
            +  ++P R   +F  +   + +  DP  L  + +  N  IM+G
Sbjct: 343 VDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLG 386


>AB028993-1|BAA83022.2|  826|Homo sapiens KIAA1070 protein protein.
          Length = 826

 Score =  126 bits (304), Expect = 2e-28
 Identities = 114/344 (33%), Positives = 163/344 (47%), Gaps = 54/344 (15%)

Query: 22  VDPLVLISNQGLVRGHKAADGDYSI-----FLGIPYAKVDVN----------NPFS---- 62
           VDPLV  +N G +RG K    +  +     FLG+PYA               +P+S    
Sbjct: 54  VDPLVA-TNFGKIRGIKKELNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPSPWSDIRN 112

Query: 63  -TATDPIAFPEIIHDAVDEVRCPQ--------TSSSVGEQTLNCLRLNIYVPSAASSRN- 112
            T   P+    II   + EV  P          SS V +Q+ +CL LNIYVP+    R+ 
Sbjct: 113 ATQFAPVCPQNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDDIRDS 172

Query: 113 --PMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYGFLCLDVPTASGNQ 169
             P PV+V+IHGG +  G+ + Y    +  +G V+V+T+NYRLG  GFL      A GN 
Sbjct: 173 GGPKPVMVYIHGGSYMEGTGNLYDGSVLASYGNVIVITVNYRLGVLGFLSTGDQAAKGNY 232

Query: 170 GLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQL--YSDNEK-------LF 219
           GL D  +AL W   NI  FGG+P  +T+ G  AG + V LL L  YS+  +       LF
Sbjct: 233 GLLDLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEGNRWSNSTKGLF 292

Query: 220 HKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKEL 279
            + I +SGT  S         + A  LA  +G N ++T E ++ L K          KEL
Sbjct: 293 QRAIAQSGTALSSWAVSFQPAKYARMLATKVGCNVSDTVELVECLQK-------KPYKEL 345

Query: 280 -ELQLKPCRER-SFSGI--SNFVESDPYSLTNKKKVRNTPIMIG 319
            +  ++P R   +F  +   + +  DP  L  + +  N  IM+G
Sbjct: 346 VDQDIQPARYHIAFGPVIDGDVIPDDPQILMEQGEFLNYDIMLG 389


>AF334270-1|AAO32948.1|  526|Homo sapiens apoptosis-related
           acetylcholinesterase protein.
          Length = 526

 Score =  123 bits (297), Expect = 1e-27
 Identities = 81/226 (35%), Positives = 125/226 (55%), Gaps = 22/226 (9%)

Query: 25  LVLISNQGLVRGH--KAADGDYSIFLGIPYAKVDVN----------NPFSTATDPIAFPE 72
           L++    G +RG   K   G  S FLGIP+A+  +            P+S   D   F  
Sbjct: 39  LLVTVRGGRLRGIRLKTPGGPVSAFLGIPFAEPPMGPRRFLPPEPKQPWSGVVDATTFQS 98

Query: 73  IIHDAVDEVRCPQTSSSVG----EQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATG 128
           + +  VD +      + +     E + +CL LN++ P    + +P PVLVWI+GG F +G
Sbjct: 99  VCYQYVDTLYPGFEGTEMWNPNRELSEDCLYLNVWTPYPRPT-SPTPVLVWIYGGGFYSG 157

Query: 129 SAS--DYGVKNIVR-HGVLVVTMNYRLGPYGFLCLDVPT-ASGNQGLRDQYKALSWIRNN 184
           ++S   Y  + +V+    ++V+MNYR+G +GFL L     A GN GL DQ  AL W++ N
Sbjct: 158 ASSLDVYDGRFLVQAERTVLVSMNYRVGAFGFLALPGSREAPGNVGLLDQRLALQWVQEN 217

Query: 185 IASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTP 229
           +A+FGG+P +VT+ G+ AGA SV + L S   + LFH+ +++SG P
Sbjct: 218 VAAFGGDPTSVTLFGESAGAASVGMHLLSPPSRGLFHRAVLQSGAP 263



 Score = 48.4 bits (110), Expect = 6e-05
 Identities = 31/119 (26%), Positives = 51/119 (42%), Gaps = 9/119 (7%)

Query: 399 LDENAGKIYEYLFSY-----SGELEDGAEHSSELNYLFETAGGSDR--TEEEQLMVDRIT 451
           L     ++Y Y+F +     S  L  G  H  E+ ++F       R  T EE++   R+ 
Sbjct: 361 LAAQGARVYAYVFEHRASTLSWPLWMGVPHGYEIEFIFGIPLDPSRNYTAEEKIFAQRLM 420

Query: 452 TLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLD-KDVRLDSRIERQRMAYWDLF 509
             W NF + G+P        P  W P TA  +  + LD + + +   +  Q  A+W+ F
Sbjct: 421 RYWANFARTGDPNEPRDPKAPQ-WPPYTAGAQQYVSLDLRPLEVRRGLRAQACAFWNRF 478


>BC034018-1|AAH34018.1|  816|Homo sapiens neuroligin 4, X-linked
           protein.
          Length = 816

 Score =  123 bits (296), Expect = 2e-27
 Identities = 73/180 (40%), Positives = 100/180 (55%), Gaps = 5/180 (2%)

Query: 90  VGEQTLNCLRLNIYVPSAAS---SRNPMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLV 145
           V +Q  +CL LNIYVP+        +  PV+V+IHGG +  G+ +      +  +G V+V
Sbjct: 139 VQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIV 198

Query: 146 VTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGAT 205
           +T+NYRLG  GFL      A GN GL DQ +AL WI  N+ +FGG+P  VTI G  AGA+
Sbjct: 199 ITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGAS 258

Query: 206 SV-LLQLYSDNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFL 264
            V LL L   +E LF K II+SGT  S         +    LA  +G N  +T + ++ L
Sbjct: 259 CVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECL 318


>AF376803-1|AAM46112.1|  816|Homo sapiens neuroligin X protein.
          Length = 816

 Score =  123 bits (296), Expect = 2e-27
 Identities = 73/180 (40%), Positives = 100/180 (55%), Gaps = 5/180 (2%)

Query: 90  VGEQTLNCLRLNIYVPSAAS---SRNPMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLV 145
           V +Q  +CL LNIYVP+        +  PV+V+IHGG +  G+ +      +  +G V+V
Sbjct: 139 VQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIV 198

Query: 146 VTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGAT 205
           +T+NYRLG  GFL      A GN GL DQ +AL WI  N+ +FGG+P  VTI G  AGA+
Sbjct: 199 ITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGAS 258

Query: 206 SV-LLQLYSDNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFL 264
            V LL L   +E LF K II+SGT  S         +    LA  +G N  +T + ++ L
Sbjct: 259 CVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECL 318


>AF376802-1|AAM46111.1|  835|Homo sapiens neuroligin 2 protein.
          Length = 835

 Score =  123 bits (296), Expect = 2e-27
 Identities = 140/514 (27%), Positives = 225/514 (43%), Gaps = 79/514 (15%)

Query: 62  STATDPIAFPEIIHDAVDEVRCP--------QTSSSVGEQTLNCLRLNIYVPSA------ 107
           +  T P A P+ +H A+  +  P          ++ V  Q+ +CL LN+YVP+       
Sbjct: 98  NATTLPPACPQNLHGALPAIMLPVWFTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTK 157

Query: 108 ---ASSRNP----------MPVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLG 153
               ++ NP           PV++++HGG +  G+ + +    +  +G V+V T+NYRLG
Sbjct: 158 KRDEATLNPPDTDIRDPGKKPVMLFLHGGSYMEGTGNMFDGSVLAAYGNVIVATLNYRLG 217

Query: 154 PYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLY 212
             GFL      A GN GL DQ +AL W+  NIA FGG+P  +TI G  AGA+ V LL L 
Sbjct: 218 VLGFLSTGDQAAKGNYGLLDQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILS 277

Query: 213 SDNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFL-TKTSPDL 271
             +E LF K I +SGT  S        ++    LA  +G +  ++ EA++ L  K S +L
Sbjct: 278 HHSEGLFQKAIAQSGTAISSWSVNYQPLKYTRLLAAKVGCDREDSAEAVECLRRKPSREL 337

Query: 272 VVAAAKELELQLKPCRER-SFSGI--SNFVESDPYSLTNKKKVRNTPIMIG-NTNK---- 323
           V       +  ++P R   +F  +   + V  DP  L  + +  N  ++IG N  +    
Sbjct: 338 V-------DQDVQPARYHIAFGPVVDGDVVPDDPEILMQQGEFLNYDMLIGVNQGEGLKF 390

Query: 324 -EKKSLSADYFSTDPFYEKLKSNF--NL---DEAQIEKAAKNVRHFYI--GDSSLSAEVA 375
            E  + S D  S   F +   SNF  NL    E + +   + ++  Y    D        
Sbjct: 391 VEDSAESEDGVSASAF-DFTVSNFVDNLYGYPEGK-DVLRETIKFMYTDWADRDNGEMRR 448

Query: 376 SELQDFESDFVYNHPSQRTITQLLDENAGKIYEYLFSYSGELED-----GAEHSSELNYL 430
             L    +D  +  P+  T  +L  +    +Y Y F +  + E       A H  EL Y+
Sbjct: 449 KTLLALFTDHQWVAPAVAT-AKLHADYQSPVYFYTFYHHCQAEGRPEWADAAHGDELPYV 507

Query: 431 F--ETAGGSDR-----TEEEQLMVDRITTLWTNFVKFGN---PTPKSTDLIPT------- 473
           F     G +D      ++ + ++   + T WTNF K G+   P P+ T  I T       
Sbjct: 508 FGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEE 567

Query: 474 -IWEPVTADTRPVLVLDKDVRLDSRIERQRMAYW 506
            +W    +  +  L +    R+       ++A+W
Sbjct: 568 VVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFW 601


>AB033086-1|BAA86574.1|  817|Homo sapiens KIAA1260 protein protein.
          Length = 817

 Score =  123 bits (296), Expect = 2e-27
 Identities = 73/180 (40%), Positives = 100/180 (55%), Gaps = 5/180 (2%)

Query: 90  VGEQTLNCLRLNIYVPSAAS---SRNPMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLV 145
           V +Q  +CL LNIYVP+        +  PV+V+IHGG +  G+ +      +  +G V+V
Sbjct: 140 VQDQNEDCLYLNIYVPTEDDIHDQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIV 199

Query: 146 VTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGAT 205
           +T+NYRLG  GFL      A GN GL DQ +AL WI  N+ +FGG+P  VTI G  AGA+
Sbjct: 200 ITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGAS 259

Query: 206 SV-LLQLYSDNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFL 264
            V LL L   +E LF K II+SGT  S         +    LA  +G N  +T + ++ L
Sbjct: 260 CVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECL 319


>BC113551-1|AAI13552.1|  816|Homo sapiens neuroligin 4, Y-linked
           protein.
          Length = 816

 Score =  122 bits (295), Expect = 2e-27
 Identities = 73/180 (40%), Positives = 99/180 (55%), Gaps = 5/180 (2%)

Query: 90  VGEQTLNCLRLNIYVP---SAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLV 145
           V +Q  +CL LNIYVP         +  PV+V+IHGG +  G+ +      +  +G V+V
Sbjct: 139 VQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIV 198

Query: 146 VTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGAT 205
           +T+NYRLG  GFL      A GN GL DQ +AL WI  N+ +FGG+P  VTI G  AGA+
Sbjct: 199 ITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGAS 258

Query: 206 SV-LLQLYSDNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFL 264
            V LL L   +E LF K II+SGT  S         +    LA  +G N  +T + ++ L
Sbjct: 259 CVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECL 318


>BC113525-1|AAI13526.1|  816|Homo sapiens neuroligin 4, Y-linked
           protein.
          Length = 816

 Score =  122 bits (295), Expect = 2e-27
 Identities = 73/180 (40%), Positives = 99/180 (55%), Gaps = 5/180 (2%)

Query: 90  VGEQTLNCLRLNIYVP---SAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLV 145
           V +Q  +CL LNIYVP         +  PV+V+IHGG +  G+ +      +  +G V+V
Sbjct: 139 VQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIV 198

Query: 146 VTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGAT 205
           +T+NYRLG  GFL      A GN GL DQ +AL WI  N+ +FGG+P  VTI G  AGA+
Sbjct: 199 ITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGAS 258

Query: 206 SV-LLQLYSDNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFL 264
            V LL L   +E LF K II+SGT  S         +    LA  +G N  +T + ++ L
Sbjct: 259 CVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECL 318


>AF376804-1|AAM46113.1|  816|Homo sapiens neuroligin Y protein.
          Length = 816

 Score =  122 bits (295), Expect = 2e-27
 Identities = 73/180 (40%), Positives = 99/180 (55%), Gaps = 5/180 (2%)

Query: 90  VGEQTLNCLRLNIYVP---SAASSRNPMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLV 145
           V +Q  +CL LNIYVP         +  PV+V+IHGG +  G+ +      +  +G V+V
Sbjct: 139 VQDQNEDCLYLNIYVPMEDDIHEQNSKKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIV 198

Query: 146 VTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGAT 205
           +T+NYRLG  GFL      A GN GL DQ +AL WI  N+ +FGG+P  VTI G  AGA+
Sbjct: 199 ITINYRLGILGFLSTGDQAAKGNYGLLDQIQALRWIEENVGAFGGDPKRVTIFGSGAGAS 258

Query: 206 SV-LLQLYSDNEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFL 264
            V LL L   +E LF K II+SGT  S         +    LA  +G N  +T + ++ L
Sbjct: 259 CVSLLTLSHYSEGLFQKAIIQSGTALSSWAVNYQPAKYTRILADKVGCNMLDTTDMVECL 318


>BX641059-1|CAE46030.1|  351|Homo sapiens hypothetical protein
           protein.
          Length = 351

 Score =  115 bits (277), Expect = 4e-25
 Identities = 76/211 (36%), Positives = 111/211 (52%), Gaps = 13/211 (6%)

Query: 115 PVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYGFLCLDVPTASGNQGLRD 173
           PV+V+IHGG +  G+ +      +  +G V+V+T+NYR+G  GFL      A GN GL D
Sbjct: 64  PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 123

Query: 174 QYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLYSDNEKLFHKVIIESGTPQSE 232
           Q +AL W+  NIA FGG+P  +T+ G   GA+ V LL L   +E LF + II+SG+  S 
Sbjct: 124 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 183

Query: 233 GMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKEL-ELQLKPCRER-S 290
                  VE    LA  +G N  +T + +  L + S       AKEL E  ++P R   +
Sbjct: 184 WAVNYQPVEYTSLLADKVGCNVLDTVDMVDCLRQKS-------AKELVEQDIQPARYHVA 236

Query: 291 FSGI--SNFVESDPYSLTNKKKVRNTPIMIG 319
           F  +   + +  DP  L  + +  N  IM+G
Sbjct: 237 FGPVIDGDVIPDDPEILMEQGEFLNYDIMLG 267


>BC051715-1|AAH51715.1|  828|Homo sapiens neuroligin 3 protein.
          Length = 828

 Score =  115 bits (277), Expect = 4e-25
 Identities = 93/289 (32%), Positives = 136/289 (47%), Gaps = 43/289 (14%)

Query: 67  PIAFPEIIHDAVDEVRCPQ--------TSSSVGEQTLNCLRLNIYVPSAASS-------- 110
           P   P+ IH AV EV  P          ++ + E   +CL LN+YVP+   S        
Sbjct: 103 PPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGED 162

Query: 111 --------------RNPMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPY 155
                             PV+V+IHGG +  G+ +      +  +G V+V+T+NYR+G  
Sbjct: 163 LADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVL 222

Query: 156 GFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLYSD 214
           GFL      A GN GL DQ +AL W+  NIA FGG+P  +T+ G   GA+ V LL L   
Sbjct: 223 GFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHH 282

Query: 215 NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVA 274
           +E LF + II+SG+  S        V+    LA  +G N  +T + +  L + S      
Sbjct: 283 SEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKS------ 336

Query: 275 AAKEL-ELQLKPCRER-SFSGI--SNFVESDPYSLTNKKKVRNTPIMIG 319
            AKEL E  ++P R   +F  +   + +  DP  L  + +  N  IM+G
Sbjct: 337 -AKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLG 384


>AF217413-2|AAF71232.1|  828|Homo sapiens neuroligin 3 isoform
           protein.
          Length = 828

 Score =  115 bits (277), Expect = 4e-25
 Identities = 93/289 (32%), Positives = 136/289 (47%), Gaps = 43/289 (14%)

Query: 67  PIAFPEIIHDAVDEVRCPQ--------TSSSVGEQTLNCLRLNIYVPSAASS-------- 110
           P   P+ IH AV EV  P          ++ + E   +CL LN+YVP+   S        
Sbjct: 103 PPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGED 162

Query: 111 --------------RNPMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPY 155
                             PV+V+IHGG +  G+ +      +  +G V+V+T+NYR+G  
Sbjct: 163 LADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVL 222

Query: 156 GFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLYSD 214
           GFL      A GN GL DQ +AL W+  NIA FGG+P  +T+ G   GA+ V LL L   
Sbjct: 223 GFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHH 282

Query: 215 NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVA 274
           +E LF + II+SG+  S        V+    LA  +G N  +T + +  L + S      
Sbjct: 283 SEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKS------ 336

Query: 275 AAKEL-ELQLKPCRER-SFSGI--SNFVESDPYSLTNKKKVRNTPIMIG 319
            AKEL E  ++P R   +F  +   + +  DP  L  + +  N  IM+G
Sbjct: 337 -AKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLG 384


>AF217413-1|AAF71233.1|  848|Homo sapiens neuroligin 3 isoform
           protein.
          Length = 848

 Score =  113 bits (273), Expect = 1e-24
 Identities = 75/211 (35%), Positives = 111/211 (52%), Gaps = 13/211 (6%)

Query: 115 PVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYGFLCLDVPTASGNQGLRD 173
           PV+V+IHGG +  G+ +      +  +G V+V+T+NYR+G  GFL      A GN GL D
Sbjct: 201 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 260

Query: 174 QYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLYSDNEKLFHKVIIESGTPQSE 232
           Q +AL W+  NIA FGG+P  +T+ G   GA+ V LL L   +E LF + II+SG+  S 
Sbjct: 261 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 320

Query: 233 GMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKEL-ELQLKPCRER-S 290
                  V+    LA  +G N  +T + +  L + S       AKEL E  ++P R   +
Sbjct: 321 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKS-------AKELVEQDIQPARYHVA 373

Query: 291 FSGI--SNFVESDPYSLTNKKKVRNTPIMIG 319
           F  +   + +  DP  L  + +  N  IM+G
Sbjct: 374 FGPVIDGDVIPDDPEILMEQGEFLNYDIMLG 404


>AF217412-1|AAF71231.1|  558|Homo sapiens neuroligin 3 isoform HNL3s
           protein.
          Length = 558

 Score =  113 bits (273), Expect = 1e-24
 Identities = 75/211 (35%), Positives = 111/211 (52%), Gaps = 13/211 (6%)

Query: 115 PVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYGFLCLDVPTASGNQGLRD 173
           PV+V+IHGG +  G+ +      +  +G V+V+T+NYR+G  GFL      A GN GL D
Sbjct: 201 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 260

Query: 174 QYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLYSDNEKLFHKVIIESGTPQSE 232
           Q +AL W+  NIA FGG+P  +T+ G   GA+ V LL L   +E LF + II+SG+  S 
Sbjct: 261 QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 320

Query: 233 GMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKEL-ELQLKPCRER-S 290
                  V+    LA  +G N  +T + +  L + S       AKEL E  ++P R   +
Sbjct: 321 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKS-------AKELVEQDIQPARYHVA 373

Query: 291 FSGI--SNFVESDPYSLTNKKKVRNTPIMIG 319
           F  +   + +  DP  L  + +  N  IM+G
Sbjct: 374 FGPVIDGDVIPDDPEILMEQGEFLNYDIMLG 404


>AB040913-1|BAA96004.1|  682|Homo sapiens KIAA1480 protein protein.
          Length = 682

 Score =  113 bits (273), Expect = 1e-24
 Identities = 75/211 (35%), Positives = 111/211 (52%), Gaps = 13/211 (6%)

Query: 115 PVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYGFLCLDVPTASGNQGLRD 173
           PV+V+IHGG +  G+ +      +  +G V+V+T+NYR+G  GFL      A GN GL D
Sbjct: 35  PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITLNYRVGVLGFLSTGDQAAKGNYGLLD 94

Query: 174 QYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLYSDNEKLFHKVIIESGTPQSE 232
           Q +AL W+  NIA FGG+P  +T+ G   GA+ V LL L   +E LF + II+SG+  S 
Sbjct: 95  QIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAIIQSGSALSS 154

Query: 233 GMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKEL-ELQLKPCRER-S 290
                  V+    LA  +G N  +T + +  L + S       AKEL E  ++P R   +
Sbjct: 155 WAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKS-------AKELVEQDIQPARYHVA 207

Query: 291 FSGI--SNFVESDPYSLTNKKKVRNTPIMIG 319
           F  +   + +  DP  L  + +  N  IM+G
Sbjct: 208 FGPVIDGDVIPDDPEILMEQGEFLNYDIMLG 238


>AF217411-1|AAF71230.1|  828|Homo sapiens neuroligin 3 isoform HNL3
           protein.
          Length = 828

 Score =  113 bits (272), Expect = 1e-24
 Identities = 93/289 (32%), Positives = 135/289 (46%), Gaps = 43/289 (14%)

Query: 67  PIAFPEIIHDAVDEVRCPQ--------TSSSVGEQTLNCLRLNIYVPSAASS-------- 110
           P   P+ IH AV EV  P          ++ + E   +CL LN+YVP+   S        
Sbjct: 103 PPVCPQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGED 162

Query: 111 --------------RNPMPVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPY 155
                             PV+V+IHGG +  G+ +         +G V+V+T+NYR+G  
Sbjct: 163 LADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSIPASYGNVIVITLNYRVGVL 222

Query: 156 GFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLYSD 214
           GFL      A GN GL DQ +AL W+  NIA FGG+P  +T+ G   GA+ V LL L   
Sbjct: 223 GFLSTGDQAAKGNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHH 282

Query: 215 NEKLFHKVIIESGTPQSEGMFVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVA 274
           +E LF + II+SG+  S        V+    LA  +G N  +T + +  L + S      
Sbjct: 283 SEGLFQRAIIQSGSALSSWAVNYQPVKYTSLLADKVGCNVLDTVDMVDCLRQKS------ 336

Query: 275 AAKEL-ELQLKPCRER-SFSGI--SNFVESDPYSLTNKKKVRNTPIMIG 319
            AKEL E  ++P R   +F  +   + +  DP  L  + +  N  IM+G
Sbjct: 337 -AKELVEQDIQPARYHVAFGPVIDGDVIPDDPEILMEQGEFLNYDIMLG 384


>AY358562-1|AAQ88925.1|  816|Homo sapiens NLGN4 protein.
          Length = 816

 Score =  110 bits (264), Expect = 1e-23
 Identities = 63/152 (41%), Positives = 86/152 (56%), Gaps = 2/152 (1%)

Query: 115 PVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYGFLCLDVPTASGNQGLRD 173
           PV+V+IHGG +  G+ +      +  +G V+V+T+NYRLG  GFL      A GN GL D
Sbjct: 168 PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLD 227

Query: 174 QYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLYSDNEKLFHKVIIESGTPQSE 232
           Q +AL WI  N+ +FGG+P  VTI G  AGA+ V LL L   +E LF K II+SGT  S 
Sbjct: 228 QIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS 287

Query: 233 GMFVNADVEAAIKLAVHLGLNTTETEEAIQFL 264
                   +    LA  +G N  +T + ++ L
Sbjct: 288 WAVNYQPAKYTRILADKVGCNMLDTTDMVECL 319


>AB023168-1|BAA76795.2|  679|Homo sapiens KIAA0951 protein protein.
          Length = 679

 Score =  110 bits (264), Expect = 1e-23
 Identities = 63/152 (41%), Positives = 86/152 (56%), Gaps = 2/152 (1%)

Query: 115 PVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYGFLCLDVPTASGNQGLRD 173
           PV+V+IHGG +  G+ +      +  +G V+V+T+NYRLG  GFL      A GN GL D
Sbjct: 30  PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILGFLSTGDQAAKGNYGLLD 89

Query: 174 QYKALSWIRNNIASFGGNPYNVTIAGQDAGATSV-LLQLYSDNEKLFHKVIIESGTPQSE 232
           Q +AL WI  N+ +FGG+P  VTI G  AGA+ V LL L   +E LF K II+SGT  S 
Sbjct: 90  QIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQKAIIQSGTALSS 149

Query: 233 GMFVNADVEAAIKLAVHLGLNTTETEEAIQFL 264
                   +    LA  +G N  +T + ++ L
Sbjct: 150 WAVNYQPAKYTRILADKVGCNMLDTTDMVECL 181


>BC131699-1|AAI31700.1|  151|Homo sapiens CES4 protein protein.
          Length = 151

 Score =  105 bits (251), Expect = 5e-22
 Identities = 58/136 (42%), Positives = 78/136 (57%), Gaps = 2/136 (1%)

Query: 117 LVWIHGGDFATGSASDY-GVKNIVRHGVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQY 175
           +VWIHGG    G+AS Y G+       V+VVT+ YRLG +GF       + GN G  DQ 
Sbjct: 1   MVWIHGGGLMVGAASTYDGLALAAHENVVVVTIQYRLGIWGFFSTGDEHSPGNCGHLDQL 60

Query: 176 KALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSDNEK-LFHKVIIESGTPQSEGM 234
            AL W+++NIASFGGNP +VTI G  AG  SV + + S   K LFH+ I ESG   +  +
Sbjct: 61  AALHWVQDNIASFGGNPGSVTIFGGSAGGESVSVLVLSPLAKNLFHRAISESGVALTSVL 120

Query: 235 FVNADVEAAIKLAVHL 250
               DV+   ++ + L
Sbjct: 121 VKKGDVKPLAEVGLRL 136


>AK097538-1|BAC05093.1|  207|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40219 fis, clone TESTI2021637, moderately
           similar to LIVER CARBOXYLESTERASE PRECURSOR (EC
           3.1.1.1). ).
          Length = 207

 Score = 97.5 bits (232), Expect = 1e-19
 Identities = 58/163 (35%), Positives = 86/163 (52%), Gaps = 2/163 (1%)

Query: 117 LVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQY 175
           +VW+HGG   TG+A+ Y    +  +G V+VVT+ YRLG  GF       A GNQG  D  
Sbjct: 1   MVWVHGGALITGAATSYDGSALAAYGDVVVVTVQYRLGVLGFFSTGDEHAPGNQGFLDVV 60

Query: 176 KALSWIRNNIASFGGNPYNVTIAGQDAGATSVL-LQLYSDNEKLFHKVIIESGTPQSEGM 234
            AL W++ NIA FGG+   VT+ G  AG + +  L L      LFH+ I +SG   + G+
Sbjct: 61  AALRWVQENIAPFGGDLNCVTVFGGSAGGSIISGLVLSPVAAGLFHRAITQSGVITTPGI 120

Query: 235 FVNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAK 277
             +     A K+A  L  +++   E +Q L +   + +V + K
Sbjct: 121 IDSHPWPLAQKIANTLACSSSSPAEMVQCLQQKEGEELVLSKK 163


>X05615-1|CAA29104.1| 2767|Homo sapiens thyroglobulin protein.
          Length = 2767

 Score = 91.5 bits (217), Expect = 7e-18
 Identities = 102/444 (22%), Positives = 191/444 (43%), Gaps = 30/444 (6%)

Query: 47   FLGIPYAKVDVNNPFSTATDPIAFPEIIHDAVDEVRCPQ----TSSSVGEQTLNCLRLNI 102
            FLG+PYA   +      A +P+ +      +     C Q    TS+S G    +CL LN+
Sbjct: 2227 FLGVPYAAPPLAERHFQAPEPLNWTGSWDASKPRASCWQPGTRTSTSPGVSE-DCLYLNV 2285

Query: 103  YVPSAASSRNPMPVLVWIHGG---DFATGSASDYGVKNIVRHGVLVVTMNYRLGPYGFLC 159
            ++P   +      VLV+ H     + + G  +  G        ++VVT +YR+G +GFL 
Sbjct: 2286 FIPQNVAPN--ASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLS 2343

Query: 160  LDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGA--TSV-LLQLYSDNE 216
                  SGN GL DQ  AL+W++ +I  FGG+P  V++A    GA   S+ LL   + N 
Sbjct: 2344 SGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNS 2403

Query: 217  KLFHKVIIESGTPQSEGMFVNAD--VEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVA 274
            +LF + ++  G+  S    ++ +   + AI LA  +    + ++E +  L +   +++  
Sbjct: 2404 QLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLND 2463

Query: 275  AAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIGNTNKE---KKSLSAD 331
            A  +L     P          +F+   P     +       ++IG++  +    ++ +  
Sbjct: 2464 AQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVK 2523

Query: 332  YF--------STDPFYEKLKSNFNLDEAQIEKAAKNVRHFYIGDSSLS-AEVASELQDFE 382
             F        S   FY+ L+++   +++     A    ++ +  S+   A  +  L++  
Sbjct: 2524 QFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENAT 2583

Query: 383  SDFVYNHPSQRTITQLLDENAGKIYEYLF--SYS-GELEDGAEHSSELNYLFETAGGSDR 439
             D+    P     +       G ++ Y    +Y  G LE  A+    L   F  A     
Sbjct: 2584 RDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQF 2643

Query: 440  TEEEQLMVDRITTLWTNFVKFGNP 463
            + EE+ +  +I   +++F++ GNP
Sbjct: 2644 SLEEKSLSLKIMQYFSHFIRSGNP 2667


>U93033-1|AAC51924.1| 2768|Homo sapiens thyroglobulin protein.
          Length = 2768

 Score = 91.5 bits (217), Expect = 7e-18
 Identities = 102/444 (22%), Positives = 191/444 (43%), Gaps = 30/444 (6%)

Query: 47   FLGIPYAKVDVNNPFSTATDPIAFPEIIHDAVDEVRCPQ----TSSSVGEQTLNCLRLNI 102
            FLG+PYA   +      A +P+ +      +     C Q    TS+S G    +CL LN+
Sbjct: 2228 FLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASCWQPGTRTSTSPGVSE-DCLYLNV 2286

Query: 103  YVPSAASSRNPMPVLVWIHGG---DFATGSASDYGVKNIVRHGVLVVTMNYRLGPYGFLC 159
            ++P   +      VLV+ H     + + G  +  G        ++VVT +YR+G +GFL 
Sbjct: 2287 FIPQNVAPN--ASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLS 2344

Query: 160  LDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGA--TSV-LLQLYSDNE 216
                  SGN GL DQ  AL+W++ +I  FGG+P  V++A    GA   S+ LL   + N 
Sbjct: 2345 SGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNS 2404

Query: 217  KLFHKVIIESGTPQSEGMFVNAD--VEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVA 274
            +LF + ++  G+  S    ++ +   + AI LA  +    + ++E +  L +   +++  
Sbjct: 2405 QLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLND 2464

Query: 275  AAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIGNTNKE---KKSLSAD 331
            A  +L     P          +F+   P     +       ++IG++  +    ++ +  
Sbjct: 2465 AQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLXVEVDLLIGSSQDDGLINRAKAVK 2524

Query: 332  YF--------STDPFYEKLKSNFNLDEAQIEKAAKNVRHFYIGDSSLS-AEVASELQDFE 382
             F        S   FY+ L+++   +++     A    ++ +  S+   A  +  L++  
Sbjct: 2525 QFEESQGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENAT 2584

Query: 383  SDFVYNHPSQRTITQLLDENAGKIYEYLF--SYS-GELEDGAEHSSELNYLFETAGGSDR 439
             D+    P     +       G ++ Y    +Y  G LE  A+    L   F  A     
Sbjct: 2585 RDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQF 2644

Query: 440  TEEEQLMVDRITTLWTNFVKFGNP 463
            + EE+ +  +I   +++F++ GNP
Sbjct: 2645 SLEEKSLSLKIMQYFSHFIRSGNP 2668


>AF080484-1|AAD50912.2| 1124|Homo sapiens thyroglobulin protein.
          Length = 1124

 Score = 90.6 bits (215), Expect = 1e-17
 Identities = 102/444 (22%), Positives = 191/444 (43%), Gaps = 30/444 (6%)

Query: 47   FLGIPYAKVDVNNPFSTATDPIAFPEIIHDAVDEVRCPQ----TSSSVGEQTLNCLRLNI 102
            FLG+PYA   +      A +P+ +      +     C Q    TS+S G    +CL LN+
Sbjct: 584  FLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASCWQPGTRTSTSPGVSE-DCLYLNV 642

Query: 103  YVPSAASSRNPMPVLVWIHGG---DFATGSASDYGVKNIVRHGVLVVTMNYRLGPYGFLC 159
            ++P   +      VLV+ H     + + G  +  G        ++VVT +YR+G +GFL 
Sbjct: 643  FIPQNVAPN--ASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLS 700

Query: 160  LDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGA--TSV-LLQLYSDNE 216
                  SGN GL DQ  AL+W++ +I  FGG+P  V++A    GA   S+ LL   + N 
Sbjct: 701  SGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNS 760

Query: 217  KLFHKVIIESGTPQSEGMFVNAD--VEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVA 274
            +LF + ++  G+  S    ++ +   + AI LA  +    + ++E +  L +   +++  
Sbjct: 761  QLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLND 820

Query: 275  AAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIGNTNKE---KKSLSAD 331
            A  +L     P          +F+   P     +       ++IG++  +    ++ +  
Sbjct: 821  AQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVK 880

Query: 332  YF--------STDPFYEKLKSNFNLDEAQIEKAAKNVRHFYIGDSSLS-AEVASELQDFE 382
             F        S   FY+ L+++   +++     A    ++ +  S+   A  +  L++  
Sbjct: 881  QFEESRGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENAT 940

Query: 383  SDFVYNHPSQRTITQLLDENAGKIYEYLF--SYS-GELEDGAEHSSELNYLFETAGGSDR 439
             D+    P     +       G ++ Y    +Y  G LE  A+    L   F  A     
Sbjct: 941  RDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQF 1000

Query: 440  TEEEQLMVDRITTLWTNFVKFGNP 463
            + EE+ +  +I   +++F++ GNP
Sbjct: 1001 SLEEKSLSLKIMQYFSHFIRSGNP 1024


>AB209159-1|BAD92396.1| 1574|Homo sapiens Thyroglobulin precursor
            variant protein.
          Length = 1574

 Score = 90.6 bits (215), Expect = 1e-17
 Identities = 102/444 (22%), Positives = 191/444 (43%), Gaps = 30/444 (6%)

Query: 47   FLGIPYAKVDVNNPFSTATDPIAFPEIIHDAVDEVRCPQ----TSSSVGEQTLNCLRLNI 102
            FLG+PYA   +      A +P+ +      +     C Q    TS+S G    +CL LN+
Sbjct: 1034 FLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASCWQPGTRTSTSPGVSE-DCLYLNV 1092

Query: 103  YVPSAASSRNPMPVLVWIHGG---DFATGSASDYGVKNIVRHGVLVVTMNYRLGPYGFLC 159
            ++P   +      VLV+ H     + + G  +  G        ++VVT +YR+G +GFL 
Sbjct: 1093 FIPQNVAPN--ASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLS 1150

Query: 160  LDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGA--TSV-LLQLYSDNE 216
                  SGN GL DQ  AL+W++ +I  FGG+P  V++A    GA   S+ LL   + N 
Sbjct: 1151 SGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNS 1210

Query: 217  KLFHKVIIESGTPQSEGMFVNAD--VEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVA 274
            +LF + ++  G+  S    ++ +   + AI LA  +    + ++E +  L +   +++  
Sbjct: 1211 QLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPANVLND 1270

Query: 275  AAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIGNTNKE---KKSLSAD 331
            A  +L     P          +F+   P     +       ++IG++  +    ++ +  
Sbjct: 1271 AQTKLLAVSGPFHYWGPVIDGHFLREPPARALKRSLWVEVDLLIGSSQDDGLINRAKAVK 1330

Query: 332  YF--------STDPFYEKLKSNFNLDEAQIEKAAKNVRHFYIGDSSLS-AEVASELQDFE 382
             F        S   FY+ L+++   +++     A    ++ +  S+   A  +  L++  
Sbjct: 1331 QFEESQGRTSSKTAFYQALQNSLGGEDSDARVEAAATWYYSLEHSTDDYASFSRALENAT 1390

Query: 383  SDFVYNHPSQRTITQLLDENAGKIYEYLF--SYS-GELEDGAEHSSELNYLFETAGGSDR 439
             D+    P     +       G ++ Y    +Y  G LE  A+    L   F  A     
Sbjct: 1391 RDYFIICPIIDMASAWAKRARGNVFMYHAPENYGHGSLELLADVQFALGLPFYPAYEGQF 1450

Query: 440  TEEEQLMVDRITTLWTNFVKFGNP 463
            + EE+ +  +I   +++F++ GNP
Sbjct: 1451 SLEEKSLSLKIMQYFSHFIRSGNP 1474


>BC127887-1|AAI27888.1|  422|Homo sapiens Unknown (protein for
           IMAGE:40133565) protein.
          Length = 422

 Score = 89.0 bits (211), Expect = 4e-17
 Identities = 68/235 (28%), Positives = 113/235 (48%), Gaps = 15/235 (6%)

Query: 47  FLGIPYAKVDVNNPFSTATDPIAFPEIIHDAVDEVRCPQ----TSSSVGEQTLNCLRLNI 102
           FLG+PYA   +      A +P+ +      +     C Q    TS+S G    +CL LN+
Sbjct: 190 FLGVPYAAPPLAERRFQAPEPLNWTGSWDASKPRASCWQPGTRTSTSPGVSE-DCLYLNV 248

Query: 103 YVPSAASSRNPMPVLVWIHGG---DFATGSASDYGVKNIVRHGVLVVTMNYRLGPYGFLC 159
           ++P   +      VLV+ H     + + G  +  G        ++VVT +YR+G +GFL 
Sbjct: 249 FIPQNVAPN--ASVLVFFHNTMDREESEGWPAIDGSFLAAVGNLIVVTASYRVGVFGFLS 306

Query: 160 LDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGA--TSV-LLQLYSDNE 216
                 SGN GL DQ  AL+W++ +I  FGG+P  V++A    GA   S+ LL   + N 
Sbjct: 307 SGSGEVSGNWGLLDQVAALTWVQTHIRGFGGDPRRVSLAADRGGADVASIHLLTARATNS 366

Query: 217 KLFHKVIIESGTPQSEGMFVNAD--VEAAIKLAVHLGLNTTETEEAIQFLTKTSP 269
           +LF + ++  G+  S    ++ +   + AI LA  +    + ++E +  L +  P
Sbjct: 367 QLFRRAVLMGGSALSPAAVISHERAQQQAIALAKEVSCPMSSSQEVVSCLRQKPP 421


>AK094783-1|BAC04422.1|  367|Homo sapiens protein ( Homo sapiens
           cDNA FLJ37464 fis, clone BRAWH2011795, weakly similar to
           LIVER CARBOXYLESTERASE PRECURSOR (EC 3.1.1.1). ).
          Length = 367

 Score = 88.2 bits (209), Expect = 6e-17
 Identities = 92/357 (25%), Positives = 154/357 (43%), Gaps = 34/357 (9%)

Query: 177 ALSWIRNNIASFGGNPYNVTIAGQDAGATSVL-LQLYSDNEKLFHKVIIESGTPQSEGMF 235
           AL W++ NIA+FGG+P NVT+ GQ AGA S+  L +      LFH+ I +SGT       
Sbjct: 3   ALRWVQENIAAFGGDPGNVTLFGQSAGAMSISGLMMSPLASGLFHRAISQSGTALFRPFI 62

Query: 236 VNADVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVVAAAKELE-LQLKPCRER----- 289
            +  ++ A K+A   G N   T+  +  L   S   V+  + ++  LQL   R+      
Sbjct: 63  TSNPLKVAKKVAHLAGCNHNSTQILVNCLRALSGTKVMRVSNKMRFLQLNFQRDPEEIIW 122

Query: 290 SFSGISN--FVESDPYSLTNKKKVRNTPIMIGNTNKE---------KKSLSADYFSTDPF 338
           S S + +   +  DP  L  + KV + P ++G  N E         K  L+      +  
Sbjct: 123 SMSPVVDGVVIPDDPLVLLTQGKVSSVPYLLGVNNLEFNWLLPYIMKFPLNRQAMRKETI 182

Query: 339 YEKLKSNFNLDEAQIEKAAKNVRHFYIGDSSLSAE-VASELQDFESDFVYNHPSQRTITQ 397
            + L S   L     E+    V  +    +    + + + + D   D  + + + +T   
Sbjct: 183 TKMLWSTRTLLNITKEQVPLVVEEYLDNVNEHDWKMLRNRMMDIVQDATFVYATLQTAHY 242

Query: 398 LLDENAGKIYEYLFSYSGE------LEDGAEHSSELNYLF--ETAGGSDRTEEEQLMVDR 449
             D     +Y Y F +           DGA+H  E+ +LF    A G    +E+ L + +
Sbjct: 243 HRDAGL-PVYLYEFEHHARGIIVKPRTDGADHGDEMYFLFGGPFATGLSMGKEKALSL-Q 300

Query: 450 ITTLWTNFVKFGNPTPKSTDLIPTIWEPVTADTRPVLVLDKDVRLDSRIERQRMAYW 506
           +   W NF + GNP   +   +P  W     D +  L LD   R+  +++ ++MA+W
Sbjct: 301 MMKYWANFARTGNPNDGN---LP-CWPRYNKDEK-YLQLDFTTRVGMKLKEKKMAFW 352


>L32179-1|AAA35551.1|  399|Homo sapiens arylacetamide deacetylase
           protein.
          Length = 399

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 51/150 (34%), Positives = 67/150 (44%), Gaps = 27/150 (18%)

Query: 79  DEVRCPQTSS---SVGEQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDYGV 135
           DEV  P TS    +V E   N + + +YVP   S       L +IHGG +  GSA+  G 
Sbjct: 69  DEV--PPTSDENVTVTETKFNNILVRVYVPKRKSEALRRG-LFYIHGGGWCVGSAALSGY 125

Query: 136 KNIVRH-----GVLVVTMNYRLGP-YGFLCLDVPTASGNQGLRDQYKALSWI--RNNIAS 187
             + R        +VV+ NYRL P Y F     P         D Y AL W   +  +A 
Sbjct: 126 DLLSRWTADRLDAVVVSTNYRLAPKYHF-----PIQ-----FEDVYNALRWFLRKKVLAK 175

Query: 188 FGGNPYNVTIAGQDAG---ATSVLLQLYSD 214
           +G NP  + I+G  AG   A +V  QL  D
Sbjct: 176 YGVNPERIGISGDSAGGNLAAAVTQQLLDD 205


>BC032309-1|AAH32309.1|  399|Homo sapiens arylacetamide deacetylase
           (esterase) protein.
          Length = 399

 Score = 47.2 bits (107), Expect = 1e-04
 Identities = 51/150 (34%), Positives = 67/150 (44%), Gaps = 27/150 (18%)

Query: 79  DEVRCPQTSS---SVGEQTLNCLRLNIYVPSAASSRNPMPVLVWIHGGDFATGSASDYGV 135
           DEV  P TS    +V E   N + + +YVP   S       L +IHGG +  GSA+  G 
Sbjct: 69  DEV--PPTSDENVTVTETKFNNILVRVYVPKRKSEALRRG-LFYIHGGGWCVGSAALSGY 125

Query: 136 KNIVRH-----GVLVVTMNYRLGP-YGFLCLDVPTASGNQGLRDQYKALSWI--RNNIAS 187
             + R        +VV+ NYRL P Y F     P         D Y AL W   +  +A 
Sbjct: 126 DLLSRWTADRLDAVVVSTNYRLAPKYHF-----PIQ-----FEDVYNALRWFLRKKVLAK 175

Query: 188 FGGNPYNVTIAGQDAG---ATSVLLQLYSD 214
           +G NP  + I+G  AG   A +V  QL  D
Sbjct: 176 YGVNPERIGISGDSAGGNLAAAVTQQLLDD 205


>BC032567-1|AAH32567.1|  134|Homo sapiens NLGN4Y protein protein.
          Length = 134

 Score = 39.5 bits (88), Expect = 0.029
 Identities = 18/43 (41%), Positives = 28/43 (65%), Gaps = 1/43 (2%)

Query: 115 PVLVWIHGGDFATGSASDYGVKNIVRHG-VLVVTMNYRLGPYG 156
           PV+V+IHGG +  G+ +      +  +G V+V+T+NYRLG  G
Sbjct: 65  PVMVYIHGGSYMEGTGNMIDGSILASYGNVIVITINYRLGILG 107


>BC132824-1|AAI32825.1|  303|Homo sapiens AFMID protein protein.
          Length = 303

 Score = 36.3 bits (80), Expect = 0.27
 Identities = 48/187 (25%), Positives = 85/187 (45%), Gaps = 32/187 (17%)

Query: 99  RLNIYVPSAASSRNPMPVLVWIHGGDFATGS--ASDYGVKNIVRHGVLVVTMNYRLGPYG 156
           +++IY P  +S    +P  ++ HGG + +GS   S + V  +   GV VV + Y + P G
Sbjct: 75  KVDIYFPDESSEA--LPFFLFFHGGYWQSGSKDESAFMVHPLTAQGVAVVIVAYGIAPKG 132

Query: 157 FLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYNVTIAGQDAGATSVLLQLYSDNE 216
            L   V   +         +++++++    S  G    + + G  AGA    + L +D  
Sbjct: 133 TLDHMVDQVT---------RSVAFVQKRYPSNKG----IYLCGHSAGAHLAAMMLLADWT 179

Query: 217 KLFHKVIIESGTPQSEGMFVNA---DVEAAIKLAVHLGLNTTETEEAIQFLTKTSPDLVV 273
           K  H V     TP   G F+ +   D+E  +  + ++ L  T  E+A     + SP L V
Sbjct: 180 K--HGV-----TPNLRGFFLVSGVFDLEPIVYTSQNVALQLT-LEDA----QRNSPQLKV 227

Query: 274 AAAKELE 280
           A A+ ++
Sbjct: 228 AQAQPVD 234


>BC003170-1|AAH03170.1| 1087|Homo sapiens ubiquitin associated protein
            2-like protein.
          Length = 1087

 Score = 33.1 bits (72), Expect = 2.5
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 142  GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYN--VTIAG 199
            GV  +   ++ GP  F     PT+S   G+     A +      + +G + YN  V++  
Sbjct: 916  GVPGLPSTFQYGPAVFPV--APTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTS 973

Query: 200  QDAGATSVLLQLYSDNEKLFHKVIIESGTP 229
             + G   +   +YS  ++ F K    SGTP
Sbjct: 974  SNTGVPDISGSVYSKTQQSFEKQGFHSGTP 1003


>AL590431-28|CAH71286.1|  382|Homo sapiens ubiquitin associated
           protein 2-like protein.
          Length = 382

 Score = 33.1 bits (72), Expect = 2.5
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYN--VTIAG 199
           GV  +   ++ GP  F     PT+S   G+     A +      + +G + YN  V++  
Sbjct: 194 GVPGLPSTFQYGPAVFPV--APTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTS 251

Query: 200 QDAGATSVLLQLYSDNEKLFHKVIIESGTP 229
            + G   +   +YS  ++ F K    SGTP
Sbjct: 252 SNTGVPDISGSVYSKTQQSFEKQGFHSGTP 281


>AL590431-27|CAH71285.1|  398|Homo sapiens ubiquitin associated
           protein 2-like protein.
          Length = 398

 Score = 33.1 bits (72), Expect = 2.5
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYN--VTIAG 199
           GV  +   ++ GP  F     PT+S   G+     A +      + +G + YN  V++  
Sbjct: 246 GVPGLPSTFQYGPAVFPV--APTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTS 303

Query: 200 QDAGATSVLLQLYSDNEKLFHKVIIESGTP 229
            + G   +   +YS  ++ F K    SGTP
Sbjct: 304 SNTGVPDISGSVYSKTQQSFEKQGFHSGTP 333


>AL590431-26|CAH71284.1| 1087|Homo sapiens ubiquitin associated
            protein 2-like protein.
          Length = 1087

 Score = 33.1 bits (72), Expect = 2.5
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 142  GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYN--VTIAG 199
            GV  +   ++ GP  F     PT+S   G+     A +      + +G + YN  V++  
Sbjct: 916  GVPGLPSTFQYGPAVFPV--APTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTS 973

Query: 200  QDAGATSVLLQLYSDNEKLFHKVIIESGTP 229
             + G   +   +YS  ++ F K    SGTP
Sbjct: 974  SNTGVPDISGSVYSKTQQSFEKQGFHSGTP 1003


>AJ243670-1|CAB65101.2|  398|Homo sapiens NICE-4 protein protein.
          Length = 398

 Score = 33.1 bits (72), Expect = 2.5
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYN--VTIAG 199
           GV  +   ++ GP  F     PT+S   G+     A +      + +G + YN  V++  
Sbjct: 246 GVPGLPSTFQYGPAVFPV--APTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTS 303

Query: 200 QDAGATSVLLQLYSDNEKLFHKVIIESGTP 229
            + G   +   +YS  ++ F K    SGTP
Sbjct: 304 SNTGVPDISGSVYSKTQQSFEKQGFHSGTP 333


>AJ243669-1|CAB65100.2|  408|Homo sapiens NICE-4 protein protein.
          Length = 408

 Score = 33.1 bits (72), Expect = 2.5
 Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 142 GVLVVTMNYRLGPYGFLCLDVPTASGNQGLRDQYKALSWIRNNIASFGGNPYN--VTIAG 199
           GV  +   ++ GP  F     PT+S   G+     A +      + +G + YN  V++  
Sbjct: 157 GVPGLPSTFQYGPAVFPV--APTSSKQHGVNVSVNASATPFQQPSGYGSHGYNTGVSVTS 214

Query: 200 QDAGATSVLLQLYSDNEKLFHKVIIESGTP 229
            + G   +   +YS  ++ F K    SGTP
Sbjct: 215 SNTGVPDISGSVYSKTQQSFEKQGFHSGTP 244


>AB037787-1|BAA92604.1|  550|Homo sapiens KIAA1366 protein protein.
          Length = 550

 Score = 31.9 bits (69), Expect = 5.8
 Identities = 25/104 (24%), Positives = 43/104 (41%), Gaps = 18/104 (17%)

Query: 421 AEHSSELNYLFET--AGGSDR-----TEEEQLMVDRITTLWTNFVKFGN---PTPKSTDL 470
           A H  EL Y+F     G +D      ++ + ++   + T WTNF K G+   P P+ T  
Sbjct: 213 AAHGDELPYVFGVPMVGATDLFPCNFSKNDVMLSAVVMTYWTNFAKTGDPNQPVPQDTKF 272

Query: 471 IPT--------IWEPVTADTRPVLVLDKDVRLDSRIERQRMAYW 506
           I T        +W    +  +  L +    R+       ++A+W
Sbjct: 273 IHTKPNRFEEVVWSKFNSKEKQYLHIGLKPRVRDNYRANKVAFW 316


>BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein.
          Length = 1291

 Score = 31.5 bits (68), Expect = 7.7
 Identities = 26/112 (23%), Positives = 50/112 (44%), Gaps = 4/112 (3%)

Query: 273 VAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---S 329
           V  A+E++ Q     E++FS IS   +SD        K +  P +  NT K K  L    
Sbjct: 436 VKRAQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLFANTEKLKAQLLQIQ 495

Query: 330 ADYFSTDPFYEKLKSNFNLDEAQIEKAAKNVRHFYIG-DSSLSAEVASELQD 380
            +  ++   YE+ K      + ++E   ++++   +  ++ L A  A + Q+
Sbjct: 496 TELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENLLEATKACKRQE 547


>AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2
           protein.
          Length = 1388

 Score = 31.5 bits (68), Expect = 7.7
 Identities = 26/112 (23%), Positives = 50/112 (44%), Gaps = 4/112 (3%)

Query: 273 VAAAKELELQLKPCRERSFSGISNFVESDPYSLTNKKKVRNTPIMIGNTNKEKKSL---S 329
           V  A+E++ Q     E++FS IS   +SD        K +  P +  NT K K  L    
Sbjct: 533 VKRAQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLFANTEKLKAQLLQIQ 592

Query: 330 ADYFSTDPFYEKLKSNFNLDEAQIEKAAKNVRHFYIG-DSSLSAEVASELQD 380
            +  ++   YE+ K      + ++E   ++++   +  ++ L A  A + Q+
Sbjct: 593 TELNNSKQEYEEFKELTRKRQLELESELQSLQKANLNLENLLEATKACKRQE 644


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.317    0.134    0.394 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 77,859,770
Number of Sequences: 224733
Number of extensions: 3317089
Number of successful extensions: 6069
Number of sequences better than 10.0: 102
Number of HSP's better than 10.0 without gapping: 89
Number of HSP's successfully gapped in prelim test: 13
Number of HSP's that attempted gapping in prelim test: 5644
Number of HSP's gapped (non-prelim): 210
length of query: 531
length of database: 73,234,838
effective HSP length: 93
effective length of query: 438
effective length of database: 52,334,669
effective search space: 22922585022
effective search space used: 22922585022
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 68 (31.5 bits)

- SilkBase 1999-2023 -