Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000872-TA|BGIBMGA000872-PA|IPR002290|Serine/threonine
protein kinase, IPR001245|Tyrosine protein kinase,
IPR000195|RabGAP/TBC, IPR000719|Protein kinase, IPR011009|Protein
kinase-like
(766 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC068496-1|AAH68496.1| 854|Homo sapiens MGC16169 protein protein. 452 e-126
BC009208-1|AAH09208.2| 830|Homo sapiens hypothetical protein MG... 452 e-126
AK098157-1|BAC05244.1| 636|Homo sapiens protein ( Homo sapiens ... 452 e-126
AK074305-1|BAB85045.1| 893|Homo sapiens protein ( Homo sapiens ... 452 e-126
AC114734-1|AAY41041.1| 534|Homo sapiens unknown protein. 416 e-115
BC020853-1|AAH20853.2| 286|Homo sapiens MGC16169 protein protein. 163 3e-39
U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein. 95 1e-18
BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2 ... 93 3e-18
U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kin... 91 1e-17
BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activate... 91 1e-17
AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B... 91 1e-17
U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kin... 91 2e-17
U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein. 89 4e-17
AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 89 4e-17
AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 89 4e-17
AL117326-3|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 89 4e-17
AL117326-2|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 89 4e-17
AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated ... 89 4e-17
AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated ... 89 4e-17
AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3 ... 89 4e-17
AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3 ... 89 4e-17
AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3 ... 89 4e-17
BC054492-1|AAH54492.1| 997|Homo sapiens RABGAP1 protein protein. 84 2e-15
AL365338-3|CAH70298.1| 997|Homo sapiens RAB GTPase activating p... 84 2e-15
AJ011679-1|CAB40267.2| 997|Homo sapiens Rab6 GTPase activating ... 84 2e-15
AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase S... 84 2e-15
AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein. 84 2e-15
AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A pr... 83 3e-15
AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protei... 83 3e-15
AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens ... 83 3e-15
AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threoni... 83 3e-15
AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threoni... 83 3e-15
AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threoni... 83 3e-15
AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threoni... 83 3e-15
AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threoni... 83 3e-15
AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kina... 83 3e-15
DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress respon... 83 4e-15
BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress respon... 83 4e-15
AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threoni... 83 4e-15
AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress respon... 83 4e-15
AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B pr... 82 8e-15
AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein. 82 8e-15
AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like pro... 82 8e-15
AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threoni... 82 8e-15
AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein. 82 8e-15
AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein. 82 8e-15
U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein... 80 3e-14
M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein. 80 3e-14
BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protei... 80 3e-14
BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protei... 80 3e-14
BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule affinit... 80 3e-14
AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule affinit... 80 3e-14
AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase ... 80 3e-14
AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein. 80 3e-14
AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein. 80 3e-14
U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kin... 79 6e-14
EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2 s... 79 6e-14
BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein k... 79 6e-14
BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein k... 79 6e-14
BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase, AMP-act... 79 6e-14
BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like ... 79 6e-14
AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase, AMP-act... 79 6e-14
AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens ... 79 6e-14
AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule affinit... 79 8e-14
AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine ... 79 8e-14
AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens ... 79 8e-14
AB088047-1|BAC03375.1| 752|Homo sapiens microtubule affinity-re... 79 8e-14
AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein. 79 8e-14
AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule affinit... 79 8e-14
X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein ... 78 1e-13
BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule affinit... 78 1e-13
BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule affinit... 78 1e-13
BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein. 78 1e-13
AL591849-3|CAI40161.1| 1178|Homo sapiens novel protein protein. 78 1e-13
AL391315-4|CAI39548.1| 1178|Homo sapiens novel protein protein. 78 1e-13
AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase ... 78 1e-13
AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase... 78 1e-13
BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein. 78 1e-13
AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein k... 78 1e-13
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 77 2e-13
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 77 2e-13
BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protei... 77 2e-13
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 77 2e-13
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 77 2e-13
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 77 2e-13
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 77 2e-13
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 77 2e-13
AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2 ... 77 2e-13
Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamm... 77 3e-13
M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase prot... 77 3e-13
BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein. 77 3e-13
BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein. 77 3e-13
BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase, g... 77 3e-13
AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule affinit... 77 3e-13
AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein. 77 3e-13
AL355341-2|CAH70583.2| 775|Homo sapiens TBC1 domain family, mem... 76 4e-13
AL138759-3|CAH70223.2| 775|Homo sapiens TBC1 domain family, mem... 76 4e-13
AB011180-1|BAA25534.1| 775|Homo sapiens KIAA0608 protein protein. 76 4e-13
AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein. 76 4e-13
BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein. 75 1e-12
BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase... 75 1e-12
AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase... 75 1e-12
AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine ... 75 1e-12
AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein. 75 1e-12
AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein. 75 1e-12
AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein. 74 2e-12
U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein. 73 3e-12
DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated prote... 73 3e-12
BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated prote... 73 3e-12
BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated prote... 73 3e-12
BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated prote... 73 3e-12
BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for IM... 73 3e-12
BC041167-1|AAH41167.1| 678|Homo sapiens TBC1 domain family, mem... 73 4e-12
AL833868-1|CAD38726.1| 381|Homo sapiens hypothetical protein pr... 73 4e-12
AB037743-1|BAA92560.1| 702|Homo sapiens KIAA1322 protein protein. 73 4e-12
BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protei... 73 5e-12
AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protei... 73 5e-12
AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threoni... 72 7e-12
Z48970-1|CAA88834.1| 303|Homo sapiens orf protein. 72 9e-12
X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein. 72 9e-12
U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein. 72 9e-12
U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4... 72 9e-12
U01038-1|AAA56634.1| 603|Homo sapiens pLK protein. 72 9e-12
M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein ... 72 9e-12
CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein. 72 9e-12
CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein. 72 9e-12
BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1 (Dro... 72 9e-12
BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase... 72 9e-12
BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase... 72 9e-12
BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase... 72 9e-12
BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1 (Dro... 72 9e-12
BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1 (Dro... 72 9e-12
AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase... 72 9e-12
Z99127-7|CAI18937.1| 815|Homo sapiens RAB GTPase activating pro... 71 1e-11
BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein. 71 1e-11
BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase, AMP-act... 71 1e-11
BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein. 71 1e-11
AY364260-1|AAQ76819.1| 468|Homo sapiens HHL protein. 71 1e-11
AL591108-1|CAH70225.1| 815|Homo sapiens RAB GTPase activating p... 71 1e-11
AL161671-6|CAI16281.1| 815|Homo sapiens RAB GTPase activating p... 71 1e-11
AL136377-4|CAI22935.1| 815|Homo sapiens RAB GTPase activating p... 71 1e-11
AL031286-3|CAI22382.1| 815|Homo sapiens RAB GTPase activating p... 71 1e-11
AL022400-4|CAI22878.1| 815|Homo sapiens RAB GTPase activating p... 71 1e-11
AL022171-4|CAI20384.1| 815|Homo sapiens RAB GTPase activating p... 71 1e-11
AK095838-1|BAC04635.1| 815|Homo sapiens protein ( Homo sapiens ... 71 1e-11
AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase... 71 1e-11
AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein. 71 1e-11
AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein. 71 1e-11
L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein. 71 2e-11
BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein. 71 2e-11
BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein. 71 2e-11
BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for IM... 71 2e-11
AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein. 71 2e-11
AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein. 71 2e-11
AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived STE20-... 71 2e-11
AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related prot... 71 2e-11
AB209179-1|BAD92416.1| 546|Homo sapiens polo-like kinase varian... 71 2e-11
AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein. 71 2e-11
U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein. 70 3e-11
BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein. 70 3e-11
AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein. 70 3e-11
AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein k... 70 3e-11
Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4... 70 4e-11
Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4... 70 4e-11
X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for ... 70 4e-11
U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein ... 70 4e-11
L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein. 70 4e-11
BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase... 70 4e-11
BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein. 70 4e-11
BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein. 70 4e-11
BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia... 70 4e-11
BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for IM... 70 4e-11
AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia... 70 4e-11
AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase... 70 4e-11
AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase... 70 4e-11
AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protei... 70 4e-11
AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase... 70 4e-11
AC016738-3|AAY14824.1| 897|Homo sapiens unknown protein. 69 5e-11
AB024057-1|BAA75489.1| 897|Homo sapiens vascular Rab-GAP/TBC-co... 69 5e-11
AB017114-1|BAA76517.1| 733|Homo sapiens AD 3 protein. 69 5e-11
U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein ... 69 6e-11
U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein. 69 6e-11
CT841514-1|CAJ86444.1| 508|Homo sapiens dJ130H16.2 protein. 69 6e-11
CR456441-1|CAG30327.1| 749|Homo sapiens dJ1042K10.2 protein. 69 6e-11
BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase... 69 6e-11
BC008078-1|AAH08078.1| 749|Homo sapiens RUN and TBC1 domain con... 69 6e-11
AY308849-1|AAQ81879.1| 749|Homo sapiens merlin binding protein ... 69 6e-11
AL022238-3|CAA18266.1| 777|Homo sapiens protein ( Human DNA seq... 69 6e-11
AK091248-1|BAC03620.1| 340|Homo sapiens protein ( Homo sapiens ... 69 6e-11
AK074656-1|BAC11117.1| 508|Homo sapiens protein ( Homo sapiens ... 69 6e-11
AK000006-1|BAA92231.1| 401|Homo sapiens FLJ00006 protein protein. 69 6e-11
AF331038-1|AAK35048.1| 508|Homo sapiens EPI64 protein. 69 6e-11
AC004997-3|AAC23434.1| 438|Homo sapiens WUGSC:H_DJ130H16.2 prot... 69 6e-11
AB196956-1|BAE02561.1| 749|Homo sapiens Rab-GTPase-activating-p... 69 6e-11
BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein. 69 8e-11
AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens ... 68 1e-10
AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b p... 68 1e-10
AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein. 68 1e-10
AB209055-1|BAD92292.1| 272|Homo sapiens phosphorylase kinase, g... 68 1e-10
AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b v... 68 1e-10
X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein ... 68 1e-10
D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein. 67 2e-10
D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein. 67 2e-10
BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase... 67 2e-10
BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein. 67 2e-10
BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase... 67 2e-10
BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein. 67 2e-10
BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein. 67 2e-10
BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein. 67 2e-10
BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase... 67 2e-10
BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leuc... 67 2e-10
AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leuc... 67 2e-10
AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related serine\/t... 67 2e-10
AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related serine\/t... 67 2e-10
AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase... 67 2e-10
AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase... 67 2e-10
AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase... 67 2e-10
AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leuc... 67 2e-10
AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related serine\/t... 67 2e-10
AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related serine\/t... 67 2e-10
AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase... 67 2e-10
AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase... 67 2e-10
AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase... 67 2e-10
AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leuc... 67 2e-10
AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20... 67 2e-10
AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-li... 67 2e-10
AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3 pro... 67 2e-10
AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein. 67 2e-10
AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens ... 67 3e-10
AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS p... 67 3e-10
X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein ... 66 3e-10
L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta pr... 66 3e-10
L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta pr... 66 3e-10
BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2 prot... 66 3e-10
BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2 prot... 66 3e-10
BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta... 66 3e-10
BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta... 66 3e-10
BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis ... 66 3e-10
BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase... 66 3e-10
AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase... 66 3e-10
AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta... 66 3e-10
AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta... 66 3e-10
AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis ... 66 3e-10
AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta... 66 3e-10
AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta... 66 3e-10
AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein. 66 3e-10
AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein. 66 3e-10
BC078179-1|AAH78179.1| 616|Homo sapiens EIF2AK4 protein protein. 66 4e-10
BC043487-1|AAH43487.1| 505|Homo sapiens calcium/calmodulin-depe... 66 4e-10
AL732423-2|CAM17479.1| 748|Homo sapiens mitogen-activated prote... 66 4e-10
AL732423-1|CAM17478.1| 788|Homo sapiens mitogen-activated prote... 66 4e-10
AL732326-2|CAM23143.1| 788|Homo sapiens mitogen-activated prote... 66 4e-10
AL732326-1|CAM23142.1| 748|Homo sapiens mitogen-activated prote... 66 4e-10
AK131412-1|BAD18559.1| 748|Homo sapiens protein ( Homo sapiens ... 66 4e-10
AF425301-1|AAN37387.1| 505|Homo sapiens CAMKK alpha protein pro... 66 4e-10
AF425232-1|AAN37386.1| 505|Homo sapiens CaMKK alpha protein pro... 66 4e-10
AF042345-1|AAC16041.1| 607|Homo sapiens truncated EVI5 protein. 66 4e-10
AF008915-1|AAC16031.1| 810|Homo sapiens EVI-5 homolog protein. 66 4e-10
AB037759-1|BAA92576.1| 1495|Homo sapiens KIAA1338 protein protein. 66 4e-10
CR542227-1|CAG47023.1| 431|Homo sapiens STK24 protein. 66 6e-10
BC038504-1|AAH38504.1| 783|Homo sapiens SNF1-like kinase protein. 66 6e-10
BC028587-1|AAH28587.1| 482|Homo sapiens NEK11 protein protein. 66 6e-10
AL354890-2|CAI21914.1| 810|Homo sapiens ecotropic viral integra... 66 6e-10
AL133332-1|CAC19437.2| 810|Homo sapiens ecotropic viral integra... 66 6e-10
AK131076-1|BAC85126.1| 764|Homo sapiens FLJ00263 protein protein. 66 6e-10
AB071997-1|BAC06351.1| 470|Homo sapiens NIMA-related kinase 11S... 66 6e-10
AB071996-1|BAC06350.1| 645|Homo sapiens NIMA-related kinase 11L... 66 6e-10
AB047786-1|BAD74070.1| 783|Homo sapiens serine/threonine protei... 66 6e-10
X78342-1|CAA55137.1| 360|Homo sapiens PISSLRE protein. 65 8e-10
U22456-1|AAA64850.1| 174|Homo sapiens AMP-activated protein kin... 65 8e-10
L33264-1|AAA60092.2| 314|Homo sapiens CDC2-related protein kina... 65 8e-10
D13644-1|BAA02807.2| 838|Homo sapiens KIAA0019 protein protein. 65 8e-10
BC042943-1|AAH42943.1| 828|Homo sapiens USP6 N-terminal like pr... 65 8e-10
BC032787-1|AAH32787.1| 476|Homo sapiens calcium/calmodulin-depe... 65 8e-10
BC025301-1|AAH25301.1| 272|Homo sapiens CDK10 protein protein. 65 8e-10
BC017342-1|AAH17342.1| 283|Homo sapiens CDK10 protein protein. 65 8e-10
BC014111-1|AAH14111.1| 794|Homo sapiens ecotropic viral integra... 65 8e-10
AY212935-1|AAP29964.1| 460|Homo sapiens CLICK III protein. 65 8e-10
AL590416-1|CAI16966.1| 828|Homo sapiens USP6 N-terminal like pr... 65 8e-10
AL512631-1|CAH70484.1| 828|Homo sapiens USP6 N-terminal like pr... 65 8e-10
AL049688-1|CAB41259.1| 481|Homo sapiens hypothetical protein pr... 65 8e-10
AL023754-3|CAI19991.1| 476|Homo sapiens calcium/calmodulin-depe... 65 8e-10
AJ010341-1|CAB37619.1| 360|Homo sapiens cyclin-dependent kinase... 65 8e-10
AF428261-1|AAL28100.1| 476|Homo sapiens calcium/calmodulin-depe... 65 8e-10
AF111105-1|AAD28547.1| 618|Homo sapiens mitogen-activated prote... 65 8e-10
U19775-1|AAC50329.1| 297|Homo sapiens Mxi2 protein. 65 1e-09
L35264-1|AAA57456.1| 360|Homo sapiens CSaids binding protein pr... 65 1e-09
L35253-1|AAA74301.1| 360|Homo sapiens MAP kinase protein. 65 1e-09
CR536505-1|CAG38743.1| 360|Homo sapiens MAPK14 protein. 65 1e-09
BT006933-1|AAP35579.1| 360|Homo sapiens mitogen-activated prote... 65 1e-09
BC125199-1|AAI25200.1| 936|Homo sapiens PKN2 protein protein. 65 1e-09
BC031574-1|AAH31574.1| 360|Homo sapiens mitogen-activated prote... 65 1e-09
BC000092-1|AAH00092.1| 360|Homo sapiens mitogen-activated prote... 65 1e-09
AF100544-1|AAF36770.1| 360|Homo sapiens stress-activated protei... 65 1e-09
AB102300-1|BAC80799.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102299-1|BAC80798.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102298-1|BAC80797.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102297-1|BAC80796.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102296-1|BAC80795.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102295-1|BAC80794.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102294-1|BAC80793.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102293-1|BAC80792.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102292-1|BAC80791.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102291-1|BAC80790.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102290-1|BAC80789.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102289-1|BAC80788.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102288-1|BAC80787.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102287-1|BAC80786.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102286-1|BAC80785.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102285-1|BAC80784.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102284-1|BAC80783.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102283-1|BAC80782.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102282-1|BAC80781.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
AB102281-1|BAC80780.1| 99|Homo sapiens p21-activated kinase 3 ... 65 1e-09
X99325-1|CAA67700.1| 426|Homo sapiens Ste20-like kinase protein. 64 1e-09
U33052-1|AAC50208.1| 984|Homo sapiens PRK2 protein. 64 1e-09
S75548-1|AAB33346.1| 984|Homo sapiens protein kinase PRK2 protein. 64 1e-09
D86968-1|BAA13204.2| 1626|Homo sapiens KIAA0213 protein. 64 1e-09
D63780-1|BAA20420.1| 426|Homo sapiens YSK1 protein. 64 1e-09
DQ093965-1|AAY88740.1| 426|Homo sapiens serine/threonine kinase... 64 1e-09
BT019961-1|AAV38764.1| 426|Homo sapiens serine/threonine kinase... 64 1e-09
BC128510-1|AAI28511.1| 1203|Homo sapiens KIAA0999 protein protein. 64 1e-09
BC091505-1|AAH91505.1| 426|Homo sapiens STK25 protein protein. 64 1e-09
BC019916-1|AAH19916.2| 506|Homo sapiens NIMA (never in mitosis ... 64 1e-09
BC015793-1|AAH15793.1| 426|Homo sapiens STK25 protein protein. 64 1e-09
BC007852-1|AAH07852.1| 426|Homo sapiens serine/threonine kinase... 64 1e-09
AL596452-3|CAI41309.1| 1498|Homo sapiens mitogen-activated prote... 64 1e-09
AL596452-2|CAI41310.1| 1544|Homo sapiens mitogen-activated prote... 64 1e-09
AL591045-2|CAH70639.1| 1498|Homo sapiens mitogen-activated prote... 64 1e-09
AL591045-1|CAH70640.1| 1544|Homo sapiens mitogen-activated prote... 64 1e-09
AL139393-2|CAI20815.1| 1498|Homo sapiens mitogen-activated prote... 64 1e-09
AL139393-1|CAI20816.1| 1544|Homo sapiens mitogen-activated prote... 64 1e-09
AL139082-7|CAI12895.1| 507|Homo sapiens NIMA (never in mitosis ... 64 1e-09
AL136381-3|CAI23271.1| 984|Homo sapiens protein kinase N2 protein. 64 1e-09
AL109942-4|CAI21477.1| 1498|Homo sapiens mitogen-activated prote... 64 1e-09
AL109942-3|CAC12766.2| 1544|Homo sapiens mitogen-activated prote... 64 1e-09
AK131477-1|BAD18622.1| 788|Homo sapiens protein ( Homo sapiens ... 64 1e-09
AK131359-1|BAD18511.1| 510|Homo sapiens protein ( Homo sapiens ... 64 1e-09
AF002715-1|AAB68804.1| 1607|Homo sapiens MAP kinase kinase kinas... 64 1e-09
AC110299-2|AAY14683.1| 426|Homo sapiens unknown protein. 64 1e-09
AB072828-1|BAC15599.1| 489|Homo sapiens NIMA-related protein ki... 64 1e-09
AB023216-1|BAA76843.2| 1371|Homo sapiens KIAA0999 protein protein. 64 1e-09
U71087-1|AAB16851.1| 448|Homo sapiens MAP kinase kinase MEK5b p... 64 2e-09
CR542229-1|CAG47025.1| 448|Homo sapiens MAP2K5 protein. 64 2e-09
BT006780-1|AAP35426.1| 448|Homo sapiens mitogen-activated prote... 64 2e-09
BC031647-1|AAH31647.1| 520|Homo sapiens calcium/calmodulin-depe... 64 2e-09
BC008838-1|AAH08838.1| 448|Homo sapiens mitogen-activated prote... 64 2e-09
Z29067-1|CAA82310.1| 459|Homo sapiens protein kinase protein. 64 2e-09
U56998-1|AAC50637.1| 607|Homo sapiens putative serine/threonine... 64 2e-09
L07861-1|AAA03175.1| 676|Homo sapiens protein kinase C-delta 13... 64 2e-09
L07860-1|AAA03176.1| 676|Homo sapiens protein kinase C-delta 13... 64 2e-09
D86965-1|BAA13201.2| 801|Homo sapiens KIAA0210 protein. 64 2e-09
D10495-1|BAA01381.1| 626|Homo sapiens protein kinase C delta-ty... 64 2e-09
CR542225-1|CAG47021.1| 372|Homo sapiens STK17B protein. 64 2e-09
BC043350-1|AAH43350.1| 676|Homo sapiens protein kinase C, delta... 64 2e-09
BC034511-1|AAH34511.1| 501|Homo sapiens PAK4 protein protein. 64 2e-09
BC025282-1|AAH25282.1| 591|Homo sapiens p21(CDKN1A)-activated k... 64 2e-09
BC013899-1|AAH13899.1| 646|Homo sapiens polo-like kinase 3 (Dro... 64 2e-09
BC013145-1|AAH13145.1| 795|Homo sapiens TBC1D5 protein protein. 64 2e-09
BC011368-1|AAH11368.1| 591|Homo sapiens p21(CDKN1A)-activated k... 64 2e-09
BC002921-1|AAH02921.1| 426|Homo sapiens p21(CDKN1A)-activated k... 64 2e-09
AY764184-1|AAU88146.1| 646|Homo sapiens polo-like kinase 3 (Dro... 64 2e-09
AL592166-11|CAI13006.1| 646|Homo sapiens polo-like kinase 3 (Dr... 64 2e-09
AK074728-1|BAC11166.1| 240|Homo sapiens protein ( Homo sapiens ... 64 2e-09
AJ293866-1|CAC10659.1| 646|Homo sapiens FNK serine/threonine pr... 64 2e-09
AJ011855-1|CAA09820.1| 591|Homo sapiens PAK4 protein protein. 64 2e-09
AF005046-1|AAD01210.1| 591|Homo sapiens serine/threonine kinase... 64 2e-09
AB209875-1|BAD93112.1| 621|Homo sapiens polo-like kinase 3 vari... 64 2e-09
AB032968-1|BAA86456.1| 467|Homo sapiens KIAA1142 protein protein. 64 2e-09
X90870-1|CAA62378.1| 458|Homo sapiens myosin-light-chain kinase... 63 3e-09
U48959-1|AAC18423.2| 1914|Homo sapiens myosin light chain kinase... 63 3e-09
U35146-1|AAC50918.1| 493|Homo sapiens p56 KKIAMRE protein kinas... 63 3e-09
M95936-1|AAA58364.1| 481|Homo sapiens protein serine/threonine ... 63 3e-09
M77198-1|AAA36585.1| 520|Homo sapiens rac protein kinase-beta p... 63 3e-09
M34182-1|AAC41690.1| 360|Homo sapiens protein kinase A gamma-su... 63 3e-09
L41816-1|AAA99458.1| 370|Homo sapiens cam kinase I protein. 63 3e-09
DQ667175-1|ABG25920.1| 351|Homo sapiens protein kinase, cAMP-de... 63 3e-09
CR542210-1|CAG47006.1| 372|Homo sapiens STK17B protein. 63 3e-09
BT020099-1|AAV38902.1| 416|Homo sapiens Mst3 and SOK1-related k... 63 3e-09
BC129951-1|AAI29952.1| 854|Homo sapiens MAP3K6 protein protein. 63 3e-09
BC129950-1|AAI29951.1| 854|Homo sapiens MAP3K6 protein protein. 63 3e-09
BC120994-1|AAI20995.1| 481|Homo sapiens v-akt murine thymoma vi... 63 3e-09
BC109032-1|AAI09033.1| 441|Homo sapiens MAP3K6 protein protein. 63 3e-09
BC106755-1|AAI06756.1| 370|Homo sapiens calcium/calmodulin-depe... 63 3e-09
BC106754-1|AAI06755.1| 370|Homo sapiens calcium/calmodulin-depe... 63 3e-09
BC103503-1|AAI03504.1| 416|Homo sapiens serine/threonine protei... 63 3e-09
BC099843-1|AAH99843.1| 416|Homo sapiens serine/threonine protei... 63 3e-09
BC098315-1|AAH98315.1| 416|Homo sapiens serine/threonine protei... 63 3e-09
BC093981-1|AAH93981.1| 493|Homo sapiens cyclin-dependent kinase... 63 3e-09
BC093646-1|AAH93646.1| 493|Homo sapiens cyclin-dependent kinase... 63 3e-09
BC039888-1|AAH39888.1| 351|Homo sapiens protein kinase, cAMP-de... 63 3e-09
BC016040-1|AAH16040.1| 372|Homo sapiens serine/threonine kinase... 63 3e-09
BC015914-1|AAH15914.1| 797|Homo sapiens MAP3K6 protein protein. 63 3e-09
AY339601-1|AAQ02673.1| 1914|Homo sapiens long myosin light chain... 63 3e-09
AP001751-1|BAA95536.1| 786|Homo sapiens SNF1LK protein. 63 3e-09
AL663123-5|CAI14778.1| 797|Homo sapiens mitogen-activated prote... 63 3e-09
AL663123-4|CAM12869.1| 1288|Homo sapiens mitogen-activated prote... 63 3e-09
AL162730-1|CAH71828.1| 351|Homo sapiens protein kinase, cAMP-de... 63 3e-09
AL109749-1|CAI42079.1| 416|Homo sapiens Mst3 and SOK1-related k... 63 3e-09
AK075150-1|BAC11435.1| 392|Homo sapiens protein ( Homo sapiens ... 63 3e-09
AJ001597-1|CAA04863.1| 351|Homo sapiens cAMP-dependent protein ... 63 3e-09
AF344882-1|AAK29620.1| 416|Homo sapiens serine/threonine protei... 63 3e-09
AF231012-1|AAK38484.1| 416|Homo sapiens STE20-like kinase MST4 ... 63 3e-09
AF100318-1|AAD05304.1| 1011|Homo sapiens mitogen-activated prote... 63 3e-09
AF069603-1|AAD15923.1| 1793|Homo sapiens myosin light chain kina... 63 3e-09
AF069602-1|AAD15922.1| 1862|Homo sapiens myosin light chain kina... 63 3e-09
AF069601-1|AAD15921.2| 1845|Homo sapiens myosin light chain kina... 63 3e-09
AC114760-2|AAY14982.1| 372|Homo sapiens unknown protein. 63 3e-09
AB208805-1|BAD92042.1| 1192|Homo sapiens mitogen-activated prote... 63 3e-09
AB167411-1|BAD12485.1| 1288|Homo sapiens apoptosis signal-regula... 63 3e-09
AB040057-1|BAA92785.2| 416|Homo sapiens serine/threonine protei... 63 3e-09
AB037663-1|BAB21504.1| 992|Homo sapiens myosin light chain kina... 63 3e-09
AB011421-1|BAA34127.1| 372|Homo sapiens DRAK2 protein. 63 3e-09
X16416-1|CAA34438.1| 1130|Homo sapiens protein ( Human c-abl mRN... 63 4e-09
U07563-2|AAB60394.1| 1130|Homo sapiens proto-oncogene tyrosine-p... 63 4e-09
U07563-1|AAB60393.1| 1149|Homo sapiens proto-oncogene tyrosine-p... 63 4e-09
L20321-1|AAA36658.1| 841|Homo sapiens protein serine/threonine ... 63 4e-09
DQ145721-1|AAZ38718.1| 1149|Homo sapiens v-abl Abelson murine le... 63 4e-09
BC117451-1|AAI17452.1| 1149|Homo sapiens v-abl Abelson murine le... 63 4e-09
BC063044-1|AAH63044.1| 781|Homo sapiens NEK4 protein protein. 63 4e-09
BC035745-1|AAH35745.1| 385|Homo sapiens calcium/calmodulin-depe... 63 4e-09
BC034988-1|AAH34988.1| 1036|Homo sapiens ULK2 protein protein. 63 4e-09
BC015515-1|AAH15515.1| 451|Homo sapiens Unknown (protein for IM... 63 4e-09
AY847283-1|AAW31760.1| 379|Homo sapiens cyclin-dependent kinase... 63 4e-09
AY845084-1|AAW30008.1| 315|Homo sapiens cyclin-dependent kinase... 63 4e-09
AL731559-2|CAI14675.1| 385|Homo sapiens calcium/calmodulin-depe... 63 4e-09
AL731559-1|CAI14674.1| 357|Homo sapiens calcium/calmodulin-depe... 63 4e-09
AL592406-2|CAH72462.1| 758|Homo sapiens MAP/microtubule affinit... 63 4e-09
AL512783-2|CAH74036.1| 385|Homo sapiens calcium/calmodulin-depe... 63 4e-09
AL512783-1|CAH74035.1| 357|Homo sapiens calcium/calmodulin-depe... 63 4e-09
AL512284-2|CAH71694.1| 385|Homo sapiens calcium/calmodulin-depe... 63 4e-09
AL512284-1|CAH71693.1| 357|Homo sapiens calcium/calmodulin-depe... 63 4e-09
AL391314-2|CAI14410.1| 385|Homo sapiens calcium/calmodulin-depe... 63 4e-09
AL391314-1|CAI14409.1| 357|Homo sapiens calcium/calmodulin-depe... 63 4e-09
AL359092-11|CAM45752.1| 1149|Homo sapiens v-abl Abelson murine l... 63 4e-09
AL161733-3|CAM45756.1| 1149|Homo sapiens v-abl Abelson murine le... 63 4e-09
AL161733-1|CAM45754.1| 1130|Homo sapiens v-abl Abelson murine le... 63 4e-09
AK027493-1|BAB55152.1| 638|Homo sapiens protein ( Homo sapiens ... 63 4e-09
AF286366-1|AAG00534.1| 357|Homo sapiens CamKI-like protein kina... 63 4e-09
AB209642-1|BAD92879.1| 949|Homo sapiens Proto-oncogene tyrosine... 63 4e-09
AB209456-1|BAD92693.1| 1167|Homo sapiens v-abl Abelson murine le... 63 4e-09
AB081726-1|BAC19846.1| 385|Homo sapiens CaM-kinase I delta prot... 63 4e-09
AB040910-1|BAA96001.1| 870|Homo sapiens KIAA1477 protein protein. 63 4e-09
AB014523-1|BAA31598.2| 1100|Homo sapiens KIAA0623 protein protein. 63 4e-09
Z15108-1|CAA78813.1| 584|Homo sapiens protein kinase C zeta pro... 62 5e-09
Y13115-1|CAA73575.1| 970|Homo sapiens serine/threonine protein ... 62 5e-09
X80229-1|CAA56515.1| 479|Homo sapiens serine/threonine protein ... 62 5e-09
U67156-1|AAC50894.1| 1374|Homo sapiens mitogen-activated kinase ... 62 5e-09
U33053-1|AAC50209.1| 942|Homo sapiens PRK1 protein. 62 5e-09
S75546-1|AAB33345.1| 942|Homo sapiens protein kinase PRK1 protein. 62 5e-09
L14283-1|AAA36488.1| 592|Homo sapiens protein kinase C zeta pro... 62 5e-09
L07597-1|AAC82497.1| 735|Homo sapiens ribosomal protein S6 kina... 62 5e-09
D84476-1|BAA12684.2| 1374|Homo sapiens apoptosis signal-regulati... 62 5e-09
D26181-1|BAA05169.1| 942|Homo sapiens PKN protein. 62 5e-09
BT007082-1|AAP35745.1| 592|Homo sapiens protein kinase C, zeta ... 62 5e-09
BC088829-1|AAH88829.1| 1374|Homo sapiens mitogen-activated prote... 62 5e-09
BC054503-1|AAH54503.1| 1374|Homo sapiens mitogen-activated prote... 62 5e-09
BC040061-1|AAH40061.1| 942|Homo sapiens protein kinase N1 protein. 62 5e-09
BC036023-1|AAH36023.1| 970|Homo sapiens polo-like kinase 4 (Dro... 62 5e-09
BC032784-1|AAH32784.1| 478|Homo sapiens calcium/calmodulin-depe... 62 5e-09
BC014966-1|AAH14966.1| 735|Homo sapiens ribosomal protein S6 ki... 62 5e-09
BC014270-1|AAH14270.1| 592|Homo sapiens protein kinase C, zeta ... 62 5e-09
BC008058-1|AAH08058.1| 592|Homo sapiens protein kinase C, zeta ... 62 5e-09
AY987011-1|AAX88806.1| 489|Homo sapiens calcium/calmodulin-depe... 62 5e-09
AL645703-1|CAI21535.1| 592|Homo sapiens protein kinase C, zeta ... 62 5e-09
AL627313-6|CAI14649.1| 735|Homo sapiens ribosomal protein S6 ki... 62 5e-09
AL590822-6|CAI12484.1| 592|Homo sapiens protein kinase C, zeta ... 62 5e-09
AL391845-5|CAI15438.1| 592|Homo sapiens protein kinase C, zeta ... 62 5e-09
AL121933-1|CAI15470.1| 1374|Homo sapiens mitogen-activated prote... 62 5e-09
AL024508-2|CAI20176.1| 1374|Homo sapiens mitogen-activated prote... 62 5e-09
AK075107-1|BAC11406.1| 339|Homo sapiens protein ( Homo sapiens ... 62 5e-09
AF071569-1|AAD20442.1| 499|Homo sapiens multifunctional calcium... 62 5e-09
AB209288-1|BAD92525.1| 522|Homo sapiens calcium/calmodulin-depe... 62 5e-09
AB209093-1|BAD92330.1| 1455|Homo sapiens mitogen-activated prote... 62 5e-09
AB006972-1|BAB69958.1| 970|Homo sapiens Sak protein. 62 5e-09
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 62 7e-09
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 62 7e-09
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 62 7e-09
L13616-1|AAA58469.1| 1052|Homo sapiens focal adhesion kinase pro... 62 7e-09
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 62 7e-09
BC128511-1|AAI28512.1| 1102|Homo sapiens KIAA0999 protein protein. 62 7e-09
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 62 7e-09
BC126979-1|AAI26980.1| 432|Homo sapiens TBC1D1 protein protein. 62 7e-09
BC114491-1|AAI14492.1| 1189|Homo sapiens NEK1 protein protein. 62 7e-09
BC109097-1|AAI09098.2| 795|Homo sapiens MLCK protein protein. 62 7e-09
BC065755-1|AAH65755.1| 234|Homo sapiens MAP3K2 protein protein. 62 7e-09
BC053648-1|AAH53648.1| 891|Homo sapiens TBC1D1 protein protein. 62 7e-09
BC050321-1|AAH50321.3| 1168|Homo sapiens TBC1 (tre-2/USP6, BUB2,... 62 7e-09
BC035782-1|AAH35782.1| 661|Homo sapiens TNK1 protein protein. 62 7e-09
BC035404-1|AAH35404.1| 1006|Homo sapiens PTK2 protein protein. 62 7e-09
BC028733-1|AAH28733.1| 680|Homo sapiens PTK2 protein protein. 62 7e-09
BC015147-1|AAH15147.1| 403|Homo sapiens Unknown (protein for IM... 62 7e-09
BC014529-1|AAH14529.1| 900|Homo sapiens TBC1D1 protein protein. 62 7e-09
AL928686-3|CAI40744.1| 283|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 62 7e-09
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 62 7e-09
>BC068496-1|AAH68496.1| 854|Homo sapiens MGC16169 protein protein.
Length = 854
Score = 452 bits (1115), Expect = e-126
Identities = 247/540 (45%), Positives = 329/540 (60%), Gaps = 56/540 (10%)
Query: 276 LQYLYHWWQLAGGDIQVELKRNGLIKNSPPILSIPVAILLDGCTIG-GKT-GVLYDRRIA 333
++ +Y+ W LAGGD++ EL +I++ PPI ++P + DG + G G+ L D
Sbjct: 283 IEEVYYLWCLAGGDLEKELVNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTV 342
Query: 334 KYSIELLQSRLSHVSAHDYYPLMHERKKQ----------NDAVTLPKTIRERDTEYQFYR 383
S+ L++RL V +YPL+ + + + A TLP IRE+DTEYQ R
Sbjct: 343 TLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIREKDTEYQLNR 402
Query: 384 LLWFQRLLHGYPYTAPYIRAEAEIDIPPLVRGDVWAALLGVVGDIEEQYERIDKETPTPT 443
++ F RLL YPY I EA +DIPPL+RG WAALLGV G I +Y+ IDK+TP PT
Sbjct: 403 IILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPT 462
Query: 444 DRQIDVDIPRCHQYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFC 503
DRQI+VDIPRCHQY LL GH +R+LKAW++++P VYWQGLDSL APF+YLNF
Sbjct: 463 DRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFN 522
Query: 504 NEARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPEL 563
NEA A+AC+SAF+PK+L+ FFLKDNS VI+EYL F QM AFH+P L+ HL++I F+P+L
Sbjct: 523 NEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDL 582
Query: 564 FAIPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILL 623
+AIPWFLTMF+HVFPLHKI HLWD L+ S P +GV IL+QLRD LL +GFNECILL
Sbjct: 583 YAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILL 642
Query: 624 FSDLPEIDIGECVKEAIDMCRSSPRSISYRRF------TNDT----------------VK 661
FSDLPEIDI CV+E+I++ +P+S +YR+ ++D+
Sbjct: 643 FSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKPSSDSSGGRSSAPYFSAECPDPP 702
Query: 662 KDSMDQVEIPMEVLFVEICPRISLSDFFSLICE------------------DKCCVVDIR 703
K + + IP+ L E+ PRIS D L CE K VVDIR
Sbjct: 703 KTDLSRESIPLNDLKSEVSPRISAEDLIDL-CELTVTGHFKTPSKKTKSSKPKLLVVDIR 761
Query: 704 SNLLYEKSCIDGSVNVPYSGVHLGRHELRALGPQPERALQQAIKMKRNVVIASAEDETAQ 763
++ + + I GS+N+P+S EL P A+ Q K K V++ TA+
Sbjct: 762 NSEDFIRGHISGSINIPFSAAFTAEGELT---QGPYTAMLQNFKGKVIVIVGHVAKHTAE 818
Score = 182 bits (442), Expect = 6e-45
Identities = 103/247 (41%), Positives = 145/247 (58%), Gaps = 26/247 (10%)
Query: 10 KFAACTFFAKSHPGETCGSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDIIRGKHERI 69
+ A TFFA + P + CGSNGLPLTP+SI ILGR Q L +I HP LC Y+DI RGKHER+
Sbjct: 8 EMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERL 67
Query: 70 IVVAEVIGKSLADL---KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLN 126
+VVAE +SL DL +K +S ++ +A +V GLQY++ + I HR LS NIL+D
Sbjct: 68 VVVAEHCERSLEDLLRERKPVSCSTVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRK 127
Query: 127 GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPETILNSGGPTADIWTFGVILLELCIGKL 186
G +KL +G+++MT G +V FP+G P YL+PE KL
Sbjct: 128 GHIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEG-----------------------RKL 164
Query: 187 WAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRAT 246
+ L L+ +L L V+D +A EH ++ ++LP+ + L+ KCL PSKR T
Sbjct: 165 FQSLDISERLKFLLTLDCVDDTLIVLAEEHGCLDIIKELPETVIDLLNKCLTFHPSKRPT 224
Query: 247 ITEILQD 253
E+++D
Sbjct: 225 PDELMKD 231
>BC009208-1|AAH09208.2| 830|Homo sapiens hypothetical protein
MGC16169 protein.
Length = 830
Score = 452 bits (1115), Expect = e-126
Identities = 247/540 (45%), Positives = 329/540 (60%), Gaps = 56/540 (10%)
Query: 276 LQYLYHWWQLAGGDIQVELKRNGLIKNSPPILSIPVAILLDGCTIG-GKT-GVLYDRRIA 333
++ +Y+ W LAGGD++ EL +I++ PPI ++P + DG + G G+ L D
Sbjct: 259 IEEVYYLWCLAGGDLEKELVNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTV 318
Query: 334 KYSIELLQSRLSHVSAHDYYPLMHERKKQ----------NDAVTLPKTIRERDTEYQFYR 383
S+ L++RL V +YPL+ + + + A TLP IRE+DTEYQ R
Sbjct: 319 TLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIREKDTEYQLNR 378
Query: 384 LLWFQRLLHGYPYTAPYIRAEAEIDIPPLVRGDVWAALLGVVGDIEEQYERIDKETPTPT 443
++ F RLL YPY I EA +DIPPL+RG WAALLGV G I +Y+ IDK+TP PT
Sbjct: 379 IILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPT 438
Query: 444 DRQIDVDIPRCHQYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFC 503
DRQI+VDIPRCHQY LL GH +R+LKAW++++P VYWQGLDSL APF+YLNF
Sbjct: 439 DRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFN 498
Query: 504 NEARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPEL 563
NEA A+AC+SAF+PK+L+ FFLKDNS VI+EYL F QM AFH+P L+ HL++I F+P+L
Sbjct: 499 NEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDL 558
Query: 564 FAIPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILL 623
+AIPWFLTMF+HVFPLHKI HLWD L+ S P +GV IL+QLRD LL +GFNECILL
Sbjct: 559 YAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILL 618
Query: 624 FSDLPEIDIGECVKEAIDMCRSSPRSISYRRF------TNDT----------------VK 661
FSDLPEIDI CV+E+I++ +P+S +YR+ ++D+
Sbjct: 619 FSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKPSSDSSGGRSSAPYFSAECPDPP 678
Query: 662 KDSMDQVEIPMEVLFVEICPRISLSDFFSLICE------------------DKCCVVDIR 703
K + + IP+ L E+ PRIS D L CE K VVDIR
Sbjct: 679 KTDLSRESIPLNDLKSEVSPRISAEDLIDL-CELTVTGHFKTPSKKTKSSKPKLLVVDIR 737
Query: 704 SNLLYEKSCIDGSVNVPYSGVHLGRHELRALGPQPERALQQAIKMKRNVVIASAEDETAQ 763
++ + + I GS+N+P+S EL P A+ Q K K V++ TA+
Sbjct: 738 NSEDFIRGHISGSINIPFSAAFTAEGELT---QGPYTAMLQNFKGKVIVIVGHVAKHTAE 794
Score = 98.3 bits (234), Expect = 9e-20
Identities = 46/77 (59%), Positives = 57/77 (74%)
Query: 10 KFAACTFFAKSHPGETCGSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDIIRGKHERI 69
+ A TFFA + P + CGSNGLPLTP+SI ILGR Q L +I HP LC Y+DI RGKHER+
Sbjct: 8 EMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERL 67
Query: 70 IVVAEVIGKSLADLKKK 86
+VVAE +SL DL ++
Sbjct: 68 VVVAEHCERSLEDLLRE 84
Score = 70.5 bits (165), Expect = 2e-11
Identities = 35/89 (39%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Query: 166 GPTADIWTFGVILLELCIG-KLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQ 224
GP +D+W+ G+IL ELC+G KL+ L L+ +L L V+D +A EH ++ ++
Sbjct: 119 GPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTLIVLAEEHGCLDIIKE 178
Query: 225 LPKYLQTLIEKCLQICPSKRATITEILQD 253
LP+ + L+ KCL PSKR T E+++D
Sbjct: 179 LPETVIDLLNKCLTFHPSKRPTPDELMKD 207
>AK098157-1|BAC05244.1| 636|Homo sapiens protein ( Homo sapiens
cDNA FLJ40838 fis, clone TRACH2013552. ).
Length = 636
Score = 452 bits (1115), Expect = e-126
Identities = 247/540 (45%), Positives = 329/540 (60%), Gaps = 56/540 (10%)
Query: 276 LQYLYHWWQLAGGDIQVELKRNGLIKNSPPILSIPVAILLDGCTIG-GKT-GVLYDRRIA 333
++ +Y+ W LAGGD++ EL +I++ PPI ++P + DG + G G+ L D
Sbjct: 65 IEEVYYLWCLAGGDLEKELVNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTV 124
Query: 334 KYSIELLQSRLSHVSAHDYYPLMHERKKQ----------NDAVTLPKTIRERDTEYQFYR 383
S+ L++RL V +YPL+ + + + A TLP IRE+DTEYQ R
Sbjct: 125 TLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIREKDTEYQLNR 184
Query: 384 LLWFQRLLHGYPYTAPYIRAEAEIDIPPLVRGDVWAALLGVVGDIEEQYERIDKETPTPT 443
++ F RLL YPY I EA +DIPPL+RG WAALLGV G I +Y+ IDK+TP PT
Sbjct: 185 IILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPT 244
Query: 444 DRQIDVDIPRCHQYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFC 503
DRQI+VDIPRCHQY LL GH +R+LKAW++++P VYWQGLDSL APF+YLNF
Sbjct: 245 DRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFN 304
Query: 504 NEARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPEL 563
NEA A+AC+SAF+PK+L+ FFLKDNS VI+EYL F QM AFH+P L+ HL++I F+P+L
Sbjct: 305 NEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDL 364
Query: 564 FAIPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILL 623
+AIPWFLTMF+HVFPLHKI HLWD L+ S P +GV IL+QLRD LL +GFNECILL
Sbjct: 365 YAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILL 424
Query: 624 FSDLPEIDIGECVKEAIDMCRSSPRSISYRRF------TNDT----------------VK 661
FSDLPEIDI CV+E+I++ +P+S +YR+ ++D+
Sbjct: 425 FSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKPSSDSSGGRSSAPYFSAECPDPP 484
Query: 662 KDSMDQVEIPMEVLFVEICPRISLSDFFSLICE------------------DKCCVVDIR 703
K + + IP+ L E+ PRIS D L CE K VVDIR
Sbjct: 485 KTDLSRESIPLNDLKSEVSPRISAEDLIDL-CELTVTGHFKTPSKKTKSSKPKLLVVDIR 543
Query: 704 SNLLYEKSCIDGSVNVPYSGVHLGRHELRALGPQPERALQQAIKMKRNVVIASAEDETAQ 763
++ + + I GS+N+P+S EL P A+ Q K K V++ TA+
Sbjct: 544 NSEDFIRGHISGSINIPFSAAFTAEGELT---QGPYTAMLQNFKGKVIVIVGHVAKHTAE 600
>AK074305-1|BAB85045.1| 893|Homo sapiens protein ( Homo sapiens
cDNA FLJ23725 fis, clone HEP14024. ).
Length = 893
Score = 452 bits (1115), Expect = e-126
Identities = 247/540 (45%), Positives = 329/540 (60%), Gaps = 56/540 (10%)
Query: 276 LQYLYHWWQLAGGDIQVELKRNGLIKNSPPILSIPVAILLDGCTIG-GKT-GVLYDRRIA 333
++ +Y+ W LAGGD++ EL +I++ PPI ++P + DG + G G+ L D
Sbjct: 322 IEEVYYLWCLAGGDLEKELVNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTV 381
Query: 334 KYSIELLQSRLSHVSAHDYYPLMHERKKQ----------NDAVTLPKTIRERDTEYQFYR 383
S+ L++RL V +YPL+ + + + A TLP IRE+DTEYQ R
Sbjct: 382 TLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIREKDTEYQLNR 441
Query: 384 LLWFQRLLHGYPYTAPYIRAEAEIDIPPLVRGDVWAALLGVVGDIEEQYERIDKETPTPT 443
++ F RLL YPY I EA +DIPPL+RG WAALLGV G I +Y+ IDK+TP PT
Sbjct: 442 IILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPT 501
Query: 444 DRQIDVDIPRCHQYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFC 503
DRQI+VDIPRCHQY LL GH +R+LKAW++++P VYWQGLDSL APF+YLNF
Sbjct: 502 DRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFN 561
Query: 504 NEARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPEL 563
NEA A+AC+SAF+PK+L+ FFLKDNS VI+EYL F QM AFH+P L+ HL++I F+P+L
Sbjct: 562 NEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDL 621
Query: 564 FAIPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILL 623
+AIPWFLTMF+HVFPLHKI HLWD L+ S P +GV IL+QLRD LL +GFNECILL
Sbjct: 622 YAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILL 681
Query: 624 FSDLPEIDIGECVKEAIDMCRSSPRSISYRRF------TNDT----------------VK 661
FSDLPEIDI CV+E+I++ +P+S +YR+ ++D+
Sbjct: 682 FSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKPSSDSSGGRSSAPYFSAECPDPP 741
Query: 662 KDSMDQVEIPMEVLFVEICPRISLSDFFSLICE------------------DKCCVVDIR 703
K + + IP+ L E+ PRIS D L CE K VVDIR
Sbjct: 742 KTDLSRESIPLNDLKSEVSPRISAEDLIDL-CELTVTGHFKTPSKKTKSSKPKLLVVDIR 800
Query: 704 SNLLYEKSCIDGSVNVPYSGVHLGRHELRALGPQPERALQQAIKMKRNVVIASAEDETAQ 763
++ + + I GS+N+P+S EL P A+ Q K K V++ TA+
Sbjct: 801 NSEDFIRGHISGSINIPFSAAFTAEGELT---QGPYTAMLQNFKGKVIVIVGHVAKHTAE 857
Score = 218 bits (532), Expect = 7e-56
Identities = 115/263 (43%), Positives = 162/263 (61%), Gaps = 19/263 (7%)
Query: 10 KFAACTFFAKSHPGETCGSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDIIRGKHERI 69
+ A TFFA + P + CGSNGLPLTP+SI ILGR Q L +I HP LC Y+DI RGKHER+
Sbjct: 8 EMGAFTFFASALPHDVCGSNGLPLTPNSIKILGRFQILKTITHPRLCQYVDISRGKHERL 67
Query: 70 IVVAEVIGKSLADL---KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLN 126
+VVAE +SL DL +K +S ++ +A +V GLQY++ + I HR LS NIL+D
Sbjct: 68 VVVAEHCERSLEDLLRERKPVSCSTVLCIAFEVLQGLQYMNKHGIVHRALSPHNILLDRK 127
Query: 127 GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPETILNS---------------GGPTADI 171
G +KL +G+++MT G +V FP+G P YL+PE I GP +D+
Sbjct: 128 GHIKLAKFGLYHMTAHGDDVDFPIGYPSYLAPEVIAQGIFKTTDHMPSKKPLPSGPKSDV 187
Query: 172 WTFGVILLELCIG-KLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQ 230
W+ G+IL ELC+G KL+ L L+ +L L V+D +A EH ++ ++LP+ +
Sbjct: 188 WSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTLIVLAEEHGCLDIIKELPETVI 247
Query: 231 TLIEKCLQICPSKRATITEILQD 253
L+ KCL PSKR T E+++D
Sbjct: 248 DLLNKCLTFHPSKRPTPDELMKD 270
>AC114734-1|AAY41041.1| 534|Homo sapiens unknown protein.
Length = 534
Score = 416 bits (1025), Expect = e-115
Identities = 199/365 (54%), Positives = 255/365 (69%), Gaps = 12/365 (3%)
Query: 276 LQYLYHWWQLAGGDIQVELKRNGLIKNSPPILSIPVAILLDGCTIG-GKT-GVLYDRRIA 333
++ +Y+ W LAGGD++ EL +I++ PPI ++P + DG + G G+ L D
Sbjct: 170 IEEVYYLWCLAGGDLEKELVNKEIIRSKPPICTLPNFLFEDGESFGQGRDRSSLLDDTTV 229
Query: 334 KYSIELLQSRLSHVSAHDYYPLMHERKKQ----------NDAVTLPKTIRERDTEYQFYR 383
S+ L++RL V +YPL+ + + + A TLP IRE+DTEYQ R
Sbjct: 230 TLSLCQLRNRLKDVGGEAFYPLLEDDQSNLPHSNSNNELSAAATLPLIIREKDTEYQLNR 289
Query: 384 LLWFQRLLHGYPYTAPYIRAEAEIDIPPLVRGDVWAALLGVVGDIEEQYERIDKETPTPT 443
++ F RLL YPY I EA +DIPPL+RG WAALLGV G I +Y+ IDK+TP PT
Sbjct: 290 IILFDRLLKAYPYKKNQIWKEARVDIPPLMRGLTWAALLGVEGAIHAKYDAIDKDTPIPT 349
Query: 444 DRQIDVDIPRCHQYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFC 503
DRQI+VDIPRCHQY LL GH +R+LKAW++++P VYWQGLDSL APF+YLNF
Sbjct: 350 DRQIEVDIPRCHQYDELLSSPEGHAKFRRVLKAWVVSHPDLVYWQGLDSLCAPFLYLNFN 409
Query: 504 NEARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPEL 563
NEA A+AC+SAF+PK+L+ FFLKDNS VI+EYL F QM AFH+P L+ HL++I F+P+L
Sbjct: 410 NEALAYACMSAFIPKYLYNFFLKDNSHVIQEYLTVFSQMIAFHDPELSNHLNEIGFIPDL 469
Query: 564 FAIPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILL 623
+AIPWFLTMF+HVFPLHKI HLWD L+ S P +GV IL+QLRD LL +GFNECILL
Sbjct: 470 YAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLRDRLLANGFNECILL 529
Query: 624 FSDLP 628
FSDLP
Sbjct: 530 FSDLP 534
Score = 69.3 bits (162), Expect = 5e-11
Identities = 34/89 (38%), Positives = 55/89 (61%), Gaps = 1/89 (1%)
Query: 166 GPTADIWTFGVILLELCIG-KLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQ 224
GP +D+W+ G+IL ELC+G KL+ L L+ +L L V+D +A EH ++ ++
Sbjct: 30 GPKSDVWSLGIILFELCVGRKLFQSLDISERLKFLLTLDCVDDTLIVLAEEHGCLDIIKE 89
Query: 225 LPKYLQTLIEKCLQICPSKRATITEILQD 253
LP+ + L+ KCL PSKR T ++++D
Sbjct: 90 LPETVIDLLNKCLTFHPSKRPTPDQLMKD 118
>BC020853-1|AAH20853.2| 286|Homo sapiens MGC16169 protein protein.
Length = 286
Score = 163 bits (395), Expect = 3e-39
Identities = 102/254 (40%), Positives = 139/254 (54%), Gaps = 44/254 (17%)
Query: 550 LATHLHDINFVPELFAIPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILRQLR 609
L+ HL++I F+P+L+AIPWFLTMF+HVFPLHKI HLWD L+ S P +GV IL+QLR
Sbjct: 1 LSNHLNEIGFIPDLYAIPWFLTMFTHVFPLHKIFHLWDTLLLGNSSFPFCIGVAILQQLR 60
Query: 610 DTLLESGFNECILLFSDLPEIDIGECVKEAIDMCRSSPRSISYRRF------TNDT---- 659
D LL +GFNECILLFSDLPEIDI CV+E+I++ +P+S +YR+ ++D+
Sbjct: 61 DRLLANGFNECILLFSDLPEIDIERCVRESINLFCWTPKSATYRQHAQPPKPSSDSSGGR 120
Query: 660 ------------VKKDSMDQVEIPMEVLFVEICPRISLSDFFSLICE------------- 694
K + + IP+ L E+ PRIS D L CE
Sbjct: 121 SSAPYFSAECPDPPKTDLSRESIPLNDLKSEVSPRISAEDLIDL-CELTVTGHFKTPSKK 179
Query: 695 -----DKCCVVDIRSNLLYEKSCIDGSVNVPYSGVHLGRHELRALGPQPERALQQAIKMK 749
K VVDIR++ + + I GS+N+P+S EL P A+ Q K K
Sbjct: 180 TKSSKPKLLVVDIRNSEDFIRGHISGSINIPFSAAFTAEGELT---QGPYTAMLQNFKGK 236
Query: 750 RNVVIASAEDETAQ 763
V++ TA+
Sbjct: 237 VIVIVGHVAKHTAE 250
>U25975-1|AAA75468.1| 493|Homo sapiens hPAK65 protein.
Length = 493
Score = 94.7 bits (225), Expect = 1e-18
Identities = 60/222 (27%), Positives = 111/222 (50%), Gaps = 15/222 (6%)
Query: 35 PSSISILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--I 92
P I+ + +++PN+ +LD E +V+ + G+SL D+ + +E I
Sbjct: 255 PKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGRSLTDVVTETCMDEAQI 314
Query: 93 INVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLG 151
V R+ L++LHAN + HR + DN+L+ + G VKL ++G +T S+ + +G
Sbjct: 315 AAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVG 374
Query: 152 QPRYLSPETILNSG-GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAK 210
P +++PE + GP DIW+ G++ +E+ G+ L P+ R L L+ N +
Sbjct: 375 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE 431
Query: 211 RIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQ 252
++ E+L + + +CL++ KR + E+LQ
Sbjct: 432 --------LQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 465
>BC069613-1|AAH69613.1| 524|Homo sapiens p21-activated kinase 2
protein.
Length = 524
Score = 93.1 bits (221), Expect = 3e-18
Identities = 60/222 (27%), Positives = 110/222 (49%), Gaps = 15/222 (6%)
Query: 35 PSSISILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--I 92
P I+ + +++PN+ +LD E +V+ + G SL D+ + +E I
Sbjct: 286 PKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETCMDEAQI 345
Query: 93 INVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLG 151
V R+ L++LHAN + HR + DN+L+ + G VKL ++G +T S+ + +G
Sbjct: 346 AAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMVG 405
Query: 152 QPRYLSPETILNSG-GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAK 210
P +++PE + GP DIW+ G++ +E+ G+ L P+ R L L+ N +
Sbjct: 406 TPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE 462
Query: 211 RIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQ 252
++ E+L + + +CL++ KR + E+LQ
Sbjct: 463 --------LQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 496
>U24153-1|AAA65442.1| 525|Homo sapiens p21-activated protein kinase
protein.
Length = 525
Score = 91.5 bits (217), Expect = 1e-17
Identities = 59/223 (26%), Positives = 110/223 (49%), Gaps = 16/223 (7%)
Query: 35 PSSISILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKK---LSTEE 91
P I+ + +++PN+ +LD E +V+ + G SL D+ + + +
Sbjct: 286 PKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVMEYLAGGSLTDVVTETACMDEAQ 345
Query: 92 IINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPL 150
I V R+ L++LHAN + HR + DN+L+ + G VKL ++G +T S+ + +
Sbjct: 346 IAAVCRECLQALEFLHANQVIHRDIKSDNVLLGMEGSVKLTDFGFCAQITPEQSKRSTMV 405
Query: 151 GQPRYLSPETILNSG-GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPA 209
G P +++PE + GP DIW+ G++ +E+ G+ L P+ R L L+ N
Sbjct: 406 GTPYWMAPEVVTRKAYGPKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTP 462
Query: 210 KRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQ 252
+ ++ E+L + + +CL++ KR + E+LQ
Sbjct: 463 E--------LQNPEKLSPIFRDFLNRCLEMDVEKRGSAKELLQ 497
>BC109299-1|AAI09300.1| 545|Homo sapiens p21/Cdc42/Rac1-activated
kinase 1 (STE20 homolog, yeast) protein.
Length = 545
Score = 91.5 bits (217), Expect = 1e-17
Identities = 59/206 (28%), Positives = 106/206 (51%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L++LH+
Sbjct: 323 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHS 382
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 383 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 442
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 443 PKVDIWSLGIMAIEMIEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPEKLS 491
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ KR + E+LQ
Sbjct: 492 AIFRDFLNRCLEMDVEKRGSAKELLQ 517
>AF071884-1|AAC24716.1| 553|Homo sapiens p21 activated kinase 1B
protein.
Length = 553
Score = 91.5 bits (217), Expect = 1e-17
Identities = 59/206 (28%), Positives = 106/206 (51%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L++LH+
Sbjct: 323 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHS 382
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 383 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 442
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 443 PKVDIWSLGIMAIEMIEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPEKLS 491
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ KR + E+LQ
Sbjct: 492 AIFRDFLNRCLEMDVEKRGSAKELLQ 517
>U24152-1|AAA65441.1| 545|Homo sapiens p21-activated protein kinase
protein.
Length = 545
Score = 90.6 bits (215), Expect = 2e-17
Identities = 59/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L++LH+
Sbjct: 323 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALEFLHS 382
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 383 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 442
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 443 PKVDIWSLGIMAIEMIEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPEKLS 491
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL + KR + E+LQ
Sbjct: 492 AIFRDFLNRCLDMDVEKRGSAKELLQ 517
>U51120-1|AAC50590.1| 545|Homo sapiens PAK1 protein.
Length = 545
Score = 89.4 bits (212), Expect = 4e-17
Identities = 59/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L+ LH+
Sbjct: 323 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALESLHS 382
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 383 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 442
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 443 PKVDIWSLGIMAIEMIEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPEKLS 491
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ KR + E+LQ
Sbjct: 492 AIFRDFLNRCLEMDVEKRGSAKELLQ 517
>AL357774-2|CAI40843.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 89.4 bits (212), Expect = 4e-17
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L +LH+
Sbjct: 321 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHS 380
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 381 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 440
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 441 PKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPERLS 489
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ +R + E+LQ
Sbjct: 490 AVFRDFLNRCLEMDVDRRGSAKELLQ 515
>AL357774-1|CAI40844.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 89.4 bits (212), Expect = 4e-17
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L +LH+
Sbjct: 336 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHS 395
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 396 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 455
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 456 PKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPERLS 504
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ +R + E+LQ
Sbjct: 505 AVFRDFLNRCLEMDVDRRGSAKELLQ 530
>AL117326-3|CAI43168.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 89.4 bits (212), Expect = 4e-17
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L +LH+
Sbjct: 336 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHS 395
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 396 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 455
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 456 PKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPERLS 504
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ +R + E+LQ
Sbjct: 505 AVFRDFLNRCLEMDVDRRGSAKELLQ 530
>AL117326-2|CAI43167.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 89.4 bits (212), Expect = 4e-17
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L +LH+
Sbjct: 321 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHS 380
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 381 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 440
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 441 PKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPERLS 489
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ +R + E+LQ
Sbjct: 490 AVFRDFLNRCLEMDVDRRGSAKELLQ 515
>AL031117-6|CAI43157.1| 544|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 544
Score = 89.4 bits (212), Expect = 4e-17
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L +LH+
Sbjct: 321 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHS 380
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 381 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 440
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 441 PKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPERLS 489
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ +R + E+LQ
Sbjct: 490 AVFRDFLNRCLEMDVDRRGSAKELLQ 515
>AL031117-5|CAI43158.1| 559|Homo sapiens p21 (CDKN1A)-activated
kinase 3 protein.
Length = 559
Score = 89.4 bits (212), Expect = 4e-17
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L +LH+
Sbjct: 336 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHS 395
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 396 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 455
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 456 PKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPERLS 504
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ +R + E+LQ
Sbjct: 505 AVFRDFLNRCLEMDVDRRGSAKELLQ 530
>AF155651-1|AAF67008.1| 544|Homo sapiens P21-activated kinase 3
protein.
Length = 544
Score = 89.4 bits (212), Expect = 4e-17
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L +LH+
Sbjct: 321 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHS 380
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 381 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 440
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 441 PKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPERLS 489
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ +R + E+LQ
Sbjct: 490 AVFRDFLNRCLEMDVDRRGSAKELLQ 515
>AF068864-1|AAC36097.1| 544|Homo sapiens p21-activated kinase 3
protein.
Length = 544
Score = 89.4 bits (212), Expect = 4e-17
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L +LH+
Sbjct: 321 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHS 380
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 381 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 440
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 441 PKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPERLS 489
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ +R + E+LQ
Sbjct: 490 AVFRDFLNRCLEMDVDRRGSAKELLQ 515
>AB102659-1|BAC81128.1| 559|Homo sapiens p21-activated kinase 3
protein.
Length = 559
Score = 89.4 bits (212), Expect = 4e-17
Identities = 58/206 (28%), Positives = 105/206 (50%), Gaps = 15/206 (7%)
Query: 51 EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--IINVARQVANGLQYLHA 108
++PN+ YLD E +V+ + G SL D+ + +E I V R+ L +LH+
Sbjct: 336 KNPNIVNYLDSYLVGDELWVVMEYLAGGSLTDVVTETCMDEGQIAAVCRECLQALDFLHS 395
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSG-G 166
N + HR + DNIL+ ++G VKL ++G +T S+ + +G P +++PE + G
Sbjct: 396 NQVIHRDIKSDNILLGMDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVTRKAYG 455
Query: 167 PTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLP 226
P DIW+ G++ +E+ G+ L P+ R L L+ N + ++ E+L
Sbjct: 456 PKVDIWSLGIMAIEMVEGEP-PYLNENPL--RALYLIATNGTPE--------LQNPERLS 504
Query: 227 KYLQTLIEKCLQICPSKRATITEILQ 252
+ + +CL++ +R + E+LQ
Sbjct: 505 AVFRDFLNRCLEMDVDRRGSAKELLQ 530
>BC054492-1|AAH54492.1| 997|Homo sapiens RABGAP1 protein protein.
Length = 997
Score = 84.2 bits (199), Expect = 2e-15
Identities = 66/224 (29%), Positives = 108/224 (48%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERIDKETPTPTDRQIDVDIPR---CHQYCWLLCG 463
+P +RG+VW L G + + E+Y RI +P D I DI R H Y + G
Sbjct: 495 VPEALRGEVWQLLAGCHNNDHLVEKY-RILITKESPQDSAITRDINRTFPAHDY-FKDTG 552
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + + Y QG L A + L E +AF+ L + + +
Sbjct: 553 GDGQDSLYKICKAYSVYDEEIGYCQGQSFLAA--VLLLHMPEEQAFSVLVKIMFDYGLRE 610
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
K N ++ KF+Q+ + P L H DI+ ++A WFLT+F+ FPL+
Sbjct: 611 LFKQN---FEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLY 667
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG S+ + +G+L+ +D LL + F + F
Sbjct: 668 MVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFF 711
>AL365338-3|CAH70298.1| 997|Homo sapiens RAB GTPase activating
protein 1 protein.
Length = 997
Score = 84.2 bits (199), Expect = 2e-15
Identities = 66/224 (29%), Positives = 108/224 (48%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERIDKETPTPTDRQIDVDIPR---CHQYCWLLCG 463
+P +RG+VW L G + + E+Y RI +P D I DI R H Y + G
Sbjct: 495 VPEALRGEVWQLLAGCHNNDHLVEKY-RILITKESPQDSAITRDINRTFPAHDY-FKDTG 552
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + + Y QG L A + L E +AF+ L + + +
Sbjct: 553 GDGQDSLYKICKAYSVYDEEIGYCQGQSFLAA--VLLLHMPEEQAFSVLVKIMFDYGLRE 610
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
K N ++ KF+Q+ + P L H DI+ ++A WFLT+F+ FPL+
Sbjct: 611 LFKQN---FEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLY 667
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG S+ + +G+L+ +D LL + F + F
Sbjct: 668 MVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFF 711
>AJ011679-1|CAB40267.2| 997|Homo sapiens Rab6 GTPase activating
protein, GAPCenA protein.
Length = 997
Score = 84.2 bits (199), Expect = 2e-15
Identities = 66/224 (29%), Positives = 108/224 (48%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERIDKETPTPTDRQIDVDIPR---CHQYCWLLCG 463
+P +RG+VW L G + + E+Y RI +P D I DI R H Y + G
Sbjct: 495 VPEALRGEVWQLLAGCHNNDHLVEKY-RILITKESPQDSAITRDINRTFPAHDY-FKDTG 552
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + + Y QG L A + L E +AF+ L + + +
Sbjct: 553 GDGQDSLYKICKAYSVYDEEIGYCQGQSFLAA--VLLLHMPEEQAFSVLVKIMFDYGLRE 610
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
K N ++ KF+Q+ + P L H DI+ ++A WFLT+F+ FPL+
Sbjct: 611 LFKQN---FEDLHCKFYQLERLMQEYIPDLYNHFLDISLEAHMYASQWFLTLFTAKFPLY 667
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG S+ + +G+L+ +D LL + F + F
Sbjct: 668 MVFHIIDLLLCEGISVIFNVALGLLKTSKDDLLLTDFEGALKFF 711
>AF099989-1|AAC72238.1| 547|Homo sapiens Ste-20 related kinase SPAK
protein.
Length = 547
Score = 83.8 bits (198), Expect = 2e-15
Identities = 70/236 (29%), Positives = 109/236 (46%), Gaps = 31/236 (13%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLST---------E 90
+L Q + HPN+ TY K E +V+ + G S+ D+ K + E
Sbjct: 108 LLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLE 167
Query: 91 EII--NVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
E I + ++V GL YLH N HR L NIL+ +G V++ ++G+ G +V
Sbjct: 168 EAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTR 227
Query: 149 P------LGQPRYLSPETILNSGGP--TADIWTFGVILLELCIGKL-WAKLKPGPILRRI 199
+G P +++PE + G AD+W+FG+ +EL G + K P ++
Sbjct: 228 NKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPP----MKV 283
Query: 200 LGLVHVNDPAKRIAREHNSIEEYEQLPKY---LQTLIEKCLQICPSKRATITEILQ 252
L L NDP +E+ E + KY + L+ CLQ PSKR T E+L+
Sbjct: 284 LMLTLQNDPPTL----ETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 335
>AC067940-1|AAY24032.1| 363|Homo sapiens unknown protein.
Length = 363
Score = 83.8 bits (198), Expect = 2e-15
Identities = 70/236 (29%), Positives = 109/236 (46%), Gaps = 31/236 (13%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLST---------E 90
+L Q + HPN+ TY K E +V+ + G S+ D+ K + E
Sbjct: 106 LLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLE 165
Query: 91 EII--NVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
E I + ++V GL YLH N HR L NIL+ +G V++ ++G+ G +V
Sbjct: 166 EAIIATILKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTR 225
Query: 149 P------LGQPRYLSPETILNSGGP--TADIWTFGVILLELCIGKL-WAKLKPGPILRRI 199
+G P +++PE + G AD+W+FG+ +EL G + K P ++
Sbjct: 226 NKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPP----MKV 281
Query: 200 LGLVHVNDPAKRIAREHNSIEEYEQLPKY---LQTLIEKCLQICPSKRATITEILQ 252
L L NDP +E+ E + KY + L+ CLQ PSKR T E+L+
Sbjct: 282 LMLTLQNDPPTL----ETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 333
>AY505125-1|AAS86443.1| 696|Homo sapiens protein kinase SAD-A
protein.
Length = 696
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 56 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 115
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+++I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 116 KEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 175
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 176 CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGAL 214
>AY166857-1|AAN87839.1| 668|Homo sapiens serine/threonine protein
kinase isoform protein.
Length = 668
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 56 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 115
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+++I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 116 KEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 175
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 176 CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGAL 214
>AK131534-1|BAD18671.1| 766|Homo sapiens protein ( Homo sapiens
cDNA FLJ16763 fis, clone BRAMY3018357, weakly similar
to SNF1-related protein kinase KIN10 (EC 2.7.1.-). ).
Length = 766
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 102 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 161
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+++I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 162 KEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 221
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 222 CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGAL 260
>AF533880-1|AAP97727.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B3 protein.
Length = 674
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 56 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 115
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+++I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 116 KEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 175
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 176 CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGAL 214
>AF533879-1|AAP97726.1| 736|Homo sapiens putative serine/threonine
protein kinase variant C protein.
Length = 736
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 56 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 115
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+++I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 116 KEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 175
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 176 CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGAL 214
>AF533878-1|AAP97725.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B2 protein.
Length = 674
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 56 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 115
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+++I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 116 KEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 175
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 176 CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGAL 214
>AF533877-1|AAP97724.1| 674|Homo sapiens putative serine/threonine
protein kinase variant B1 protein.
Length = 674
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 56 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 115
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+++I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 116 KEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 175
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 176 CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGAL 214
>AF533876-1|AAP97723.1| 668|Homo sapiens putative serine/threonine
protein kinase variant A protein.
Length = 668
Score = 83.4 bits (197), Expect = 3e-15
Identities = 49/159 (30%), Positives = 82/159 (51%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 56 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 115
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+++I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 116 KEARKFFRQIISALDFCHSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 175
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 176 CGSPHYACPEVIRGEKYDGRKADVWSCGVILFALLVGAL 214
>AF030403-1|AAD01901.1| 547|Homo sapiens Ste20-like protein kinase
protein.
Length = 547
Score = 83.4 bits (197), Expect = 3e-15
Identities = 70/236 (29%), Positives = 109/236 (46%), Gaps = 31/236 (13%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLST---------E 90
+L Q + HPN+ TY K E +V+ + G S+ D+ K + E
Sbjct: 108 LLKEIQAMSQCSHPNVVTYYTSFVVKDELWLVMKLLSGGSMLDIIKYIVNRGEHKNGVLE 167
Query: 91 EII--NVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
E I + ++V GL YLH N HR L NIL+ +G V++ ++G+ G +V
Sbjct: 168 EAIIATIFKEVLEGLDYLHRNGQIHRDLKAGNILLGEDGSVQIADFGVSAFLATGGDVTR 227
Query: 149 P------LGQPRYLSPETILNSGGP--TADIWTFGVILLELCIGKL-WAKLKPGPILRRI 199
+G P +++PE + G AD+W+FG+ +EL G + K P ++
Sbjct: 228 NKVRKTFVGTPCWMAPEVMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPP----MKV 283
Query: 200 LGLVHVNDPAKRIAREHNSIEEYEQLPKY---LQTLIEKCLQICPSKRATITEILQ 252
L L NDP +E+ E + KY + L+ CLQ PSKR T E+L+
Sbjct: 284 LMLTLQNDPPTL----ETGVEDKEMMKKYGKSFRKLLSLCLQKDPSKRPTAAELLK 335
>DQ201638-1|ABA27097.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 83.0 bits (196), Expect = 4e-15
Identities = 67/236 (28%), Positives = 107/236 (45%), Gaps = 31/236 (13%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKK-----------LS 88
+L Q + HPN+ +Y K E +V+ + G S+ D+ K L
Sbjct: 60 LLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLD 119
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
I + R+V GL+YLH N HR + NIL+ +G V++ ++G+ G ++
Sbjct: 120 ESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITR 179
Query: 149 P------LGQPRYLSPETILNSGGP--TADIWTFGVILLELCIGKL-WAKLKPGPILRRI 199
+G P +++PE + G ADIW+FG+ +EL G + K P ++
Sbjct: 180 NKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPP----MKV 235
Query: 200 LGLVHVNDPAKRIAREHNSIEEYEQLPKY---LQTLIEKCLQICPSKRATITEILQ 252
L L NDP +++ E L KY + +I CLQ P KR T E+L+
Sbjct: 236 LMLTLQNDPPSL----ETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>BC008726-1|AAH08726.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 83.0 bits (196), Expect = 4e-15
Identities = 67/236 (28%), Positives = 107/236 (45%), Gaps = 31/236 (13%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKK-----------LS 88
+L Q + HPN+ +Y K E +V+ + G S+ D+ K L
Sbjct: 60 LLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLD 119
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
I + R+V GL+YLH N HR + NIL+ +G V++ ++G+ G ++
Sbjct: 120 ESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITR 179
Query: 149 P------LGQPRYLSPETILNSGGP--TADIWTFGVILLELCIGKL-WAKLKPGPILRRI 199
+G P +++PE + G ADIW+FG+ +EL G + K P ++
Sbjct: 180 NKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPP----MKV 235
Query: 200 LGLVHVNDPAKRIAREHNSIEEYEQLPKY---LQTLIEKCLQICPSKRATITEILQ 252
L L NDP +++ E L KY + +I CLQ P KR T E+L+
Sbjct: 236 LMLTLQNDPPSL----ETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>AJ006701-1|CAA07196.1| 603|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 603
Score = 83.0 bits (196), Expect = 4e-15
Identities = 45/142 (31%), Positives = 73/142 (51%), Gaps = 5/142 (3%)
Query: 50 IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGLQYL 106
IEHP++ D+ K +V+ V G L D K +L+ +E RQ+ + L +
Sbjct: 2 IEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTPKEARKFFRQIISALDFC 61
Query: 107 HANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPETILNS-- 164
H+++I HR L +N+L+D +++ ++G+ + G S + G P Y PE I
Sbjct: 62 HSHSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETSCGSPHYACPEVIRGEKY 121
Query: 165 GGPTADIWTFGVILLELCIGKL 186
G AD+W+ GVIL L +G L
Sbjct: 122 DGRKADVWSCGVILFALLVGAL 143
>AB017642-1|BAA75674.1| 527|Homo sapiens oxidative-stress
responsive 1 protein.
Length = 527
Score = 83.0 bits (196), Expect = 4e-15
Identities = 67/236 (28%), Positives = 107/236 (45%), Gaps = 31/236 (13%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKK-----------LS 88
+L Q + HPN+ +Y K E +V+ + G S+ D+ K L
Sbjct: 60 LLKEIQAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLD 119
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
I + R+V GL+YLH N HR + NIL+ +G V++ ++G+ G ++
Sbjct: 120 ESTIATILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITR 179
Query: 149 P------LGQPRYLSPETILNSGGP--TADIWTFGVILLELCIGKL-WAKLKPGPILRRI 199
+G P +++PE + G ADIW+FG+ +EL G + K P ++
Sbjct: 180 NKVRKTFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPP----MKV 235
Query: 200 LGLVHVNDPAKRIAREHNSIEEYEQLPKY---LQTLIEKCLQICPSKRATITEILQ 252
L L NDP +++ E L KY + +I CLQ P KR T E+L+
Sbjct: 236 LMLTLQNDPPSL----ETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 287
>AY505124-1|AAS86442.1| 778|Homo sapiens protein kinase SAD-B
protein.
Length = 778
Score = 81.8 bits (193), Expect = 8e-15
Identities = 49/159 (30%), Positives = 81/159 (50%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 71 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 130
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+ +I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 131 KEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 190
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 191 CGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGAL 229
>AY458602-1|AAS10354.1| 778|Homo sapiens SAD1 kinase protein.
Length = 778
Score = 81.8 bits (193), Expect = 8e-15
Identities = 49/159 (30%), Positives = 81/159 (50%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 71 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 130
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+ +I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 131 KEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 190
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 191 CGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGAL 229
>AF479827-1|AAL87698.1| 778|Homo sapiens protein kinase-like
protein protein.
Length = 778
Score = 81.8 bits (193), Expect = 8e-15
Identities = 49/159 (30%), Positives = 81/159 (50%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 71 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 130
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+ +I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 131 KEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 190
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 191 CGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGAL 229
>AF479826-1|AAL87697.1| 794|Homo sapiens putative serine/threonine
protein kinase protein.
Length = 794
Score = 81.8 bits (193), Expect = 8e-15
Identities = 49/159 (30%), Positives = 81/159 (50%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 87 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 146
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+ +I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 147 KEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 206
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 207 CGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGAL 245
>AB058714-1|BAB47440.1| 715|Homo sapiens KIAA1811 protein protein.
Length = 715
Score = 81.8 bits (193), Expect = 8e-15
Identities = 49/159 (30%), Positives = 81/159 (50%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQRLLSI----EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S S+L + +R ++I EHP++ D+ K +V+ V G L D K +L+
Sbjct: 8 SESVLMKVEREIAILKLIEHPHVLKLHDVYENKKYLYLVLEHVSGGELFDYLVKKGRLTP 67
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E RQ+ + L + H+ +I HR L +N+L+D +++ ++G+ + G S +
Sbjct: 68 KEARKFFRQIVSALDFCHSYSICHRDLKPENLLLDEKNNIRIADFGMASLQVGDSLLETS 127
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y PE I G AD+W+ GVIL L +G L
Sbjct: 128 CGSPHYACPEVIKGEKYDGRRADMWSCGVILFALLVGAL 166
>AB029024-1|BAA83053.2| 467|Homo sapiens KIAA1101 protein protein.
Length = 467
Score = 81.8 bits (193), Expect = 8e-15
Identities = 66/231 (28%), Positives = 105/231 (45%), Gaps = 31/231 (13%)
Query: 45 QRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKK-----------LSTEEII 93
Q + HPN+ +Y K E +V+ + G S+ D+ K L I
Sbjct: 5 QAMSQCHHPNIVSYYTSFVVKDELWLVMKLLSGGSVLDIIKHIVAKGEHKSGVLDESTIA 64
Query: 94 NVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP---- 149
+ R+V GL+YLH N HR + NIL+ +G V++ ++G+ G ++
Sbjct: 65 TILREVLEGLEYLHKNGQIHRDVKAGNILLGEDGSVQIADFGVSAFLATGGDITRNKVRK 124
Query: 150 --LGQPRYLSPETILNSGGP--TADIWTFGVILLELCIGKL-WAKLKPGPILRRILGLVH 204
+G P +++PE + G ADIW+FG+ +EL G + K P ++L L
Sbjct: 125 TFVGTPCWMAPEVMEQVRGYDFKADIWSFGITAIELATGAAPYHKYPP----MKVLMLTL 180
Query: 205 VNDPAKRIAREHNSIEEYEQLPKY---LQTLIEKCLQICPSKRATITEILQ 252
NDP +++ E L KY + +I CLQ P KR T E+L+
Sbjct: 181 QNDPPSL----ETGVQDKEMLKKYGKSFRKMISLCLQKDPEKRPTAAELLR 227
>U64205-1|AAC15093.1| 729|Homo sapiens Cdc25C associated protein
kinase C-TAK1 protein.
Length = 729
Score = 80.2 bits (189), Expect = 3e-14
Identities = 61/228 (26%), Positives = 107/228 (46%), Gaps = 22/228 (9%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L P+S+ L R R++ I HPN+ ++I + +++ G + D ++
Sbjct: 92 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMK 151
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF-YMTYGGSEVA 147
+E + RQ+ + +QY H I HR L +N+L+D + +K+ ++G T GG
Sbjct: 152 EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDT 211
Query: 148 FPLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHV 205
F G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 212 F-CGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NL 258
Query: 206 NDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L+++ L + P KR T+ +I++D
Sbjct: 259 KELRERVLRGKYRIPFY--MSTDCENLLKRFLVLNPIKRGTLEQIMKD 304
>M80359-1|AAA59991.1| 713|Homo sapiens protein p78 protein.
Length = 713
Score = 80.2 bits (189), Expect = 3e-14
Identities = 61/228 (26%), Positives = 107/228 (46%), Gaps = 22/228 (9%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L P+S+ L R R++ I HPN+ ++I + +++ G + D ++
Sbjct: 92 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETQKTLYLIMEYASGGKVFDYLVAHGRMK 151
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF-YMTYGGSEVA 147
+E + RQ+ + +QY H I HR L +N+L+D + +K+ ++G T GG
Sbjct: 152 EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDT 211
Query: 148 FPLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHV 205
F G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 212 F-CGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NL 258
Query: 206 NDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L+++ L + P KR T+ +I++D
Sbjct: 259 KELRERVLRGKYRIPFY--MSTDCENLLKRFLVLNPIKRGTLEQIMKD 304
>BC126432-1|AAI26433.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 80.2 bits (189), Expect = 3e-14
Identities = 48/146 (32%), Positives = 76/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I HPN+ T DI K + ++++ V G L D K+ L+ +E +Q+ +G+
Sbjct: 68 LREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDL---NGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++KL ++GI + G+E G P +++PE
Sbjct: 128 HYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>BC126430-1|AAI26431.1| 454|Homo sapiens death-associated protein
kinase 3 protein.
Length = 454
Score = 80.2 bits (189), Expect = 3e-14
Identities = 48/146 (32%), Positives = 76/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I HPN+ T DI K + ++++ V G L D K+ L+ +E +Q+ +G+
Sbjct: 68 LREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDL---NGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++KL ++GI + G+E G P +++PE
Sbjct: 128 HYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>BC024773-1|AAH24773.1| 729|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 protein.
Length = 729
Score = 80.2 bits (189), Expect = 3e-14
Identities = 61/228 (26%), Positives = 107/228 (46%), Gaps = 22/228 (9%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L P+S+ L R R++ I HPN+ ++I + +++ G + D ++
Sbjct: 92 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMK 151
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF-YMTYGGSEVA 147
+E + RQ+ + +QY H I HR L +N+L+D + +K+ ++G T GG
Sbjct: 152 EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDT 211
Query: 148 FPLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHV 205
F G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 212 F-CGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NL 258
Query: 206 NDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L+++ L + P KR T+ +I++D
Sbjct: 259 KELRERVLRGKYRIPFY--MSTDCENLLKRFLVLNPIKRGTLEQIMKD 304
>AF465413-1|AAL69982.1| 753|Homo sapiens MAP/microtubule
affinity-regulating kinase 3 long isoform protein.
Length = 753
Score = 80.2 bits (189), Expect = 3e-14
Identities = 61/228 (26%), Positives = 107/228 (46%), Gaps = 22/228 (9%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L P+S+ L R R++ I HPN+ ++I + +++ G + D ++
Sbjct: 92 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGKVFDYLVAHGRMK 151
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF-YMTYGGSEVA 147
+E + RQ+ + +QY H I HR L +N+L+D + +K+ ++G T GG
Sbjct: 152 EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDT 211
Query: 148 FPLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHV 205
F G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 212 F-CGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NL 258
Query: 206 NDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L+++ L + P KR T+ +I++D
Sbjct: 259 KELRERVLRGKYRIPFY--MSTDCENLLKRFLVLNPIKRGTLEQIMKD 304
>AF387637-1|AAK82367.1| 744|Homo sapiens Ser/Thr protein kinase
PAR-1A protein.
Length = 744
Score = 80.2 bits (189), Expect = 3e-14
Identities = 61/228 (26%), Positives = 107/228 (46%), Gaps = 22/228 (9%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L P+S+ L R R++ I HPN+ ++I + +++ G + D ++
Sbjct: 92 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLIMEYASGGEVFDYLVAHGRMK 151
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF-YMTYGGSEVA 147
+E + RQ+ + +QY H I HR L +N+L+D + +K+ ++G T GG
Sbjct: 152 EKEARSKFRQIVSAVQYCHQKRIVHRDLKAENLLLDADMNIKIADFGFSNEFTVGGKLDT 211
Query: 148 FPLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHV 205
F G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 212 F-CGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NL 258
Query: 206 NDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L+++ L + P KR T+ +I++D
Sbjct: 259 KELRERVLRGKYRIPFY--MSTDCENLLKRFLVLNPIKRGTLEQIMKD 304
>AB022341-1|BAA81746.1| 454|Homo sapiens ZIP kinase protein.
Length = 454
Score = 80.2 bits (189), Expect = 3e-14
Identities = 48/146 (32%), Positives = 76/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I HPN+ T DI K + ++++ V G L D K+ L+ +E +Q+ +G+
Sbjct: 68 LREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDL---NGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++KL ++GI + G+E G P +++PE
Sbjct: 128 HYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>AB007144-1|BAA24955.1| 454|Homo sapiens ZIP-kinase protein.
Length = 454
Score = 80.2 bits (189), Expect = 3e-14
Identities = 48/146 (32%), Positives = 76/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I HPN+ T DI K + ++++ V G L D K+ L+ +E +Q+ +G+
Sbjct: 68 LREIRHPNIITLHDIFENKTDVVLILELVSGGELFDFLAEKESLTEDEATQFLKQILDGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDL---NGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++KL ++GI + G+E G P +++PE
Sbjct: 128 HYLHSKRIAHFDLKPENIMLLDKNVPNPRIKLIDFGIAHKIEAGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>U06454-1|AAA64745.1| 552|Homo sapiens AMP-activated protein kinase
protein.
Length = 552
Score = 79.0 bits (186), Expect = 6e-14
Identities = 66/223 (29%), Positives = 100/223 (44%), Gaps = 23/223 (10%)
Query: 37 SISILGRAQR----LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEEI 92
S+ ++G+ +R L HP++ +I + +V+ V G L D K E
Sbjct: 54 SLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEE 113
Query: 93 INVAR---QVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+ R Q+ + + Y H + + HR L +N+L+D + K+ ++G+ M G +
Sbjct: 114 MEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTS 173
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVND 207
G P Y +PE I GP DIW+ GVIL L G L P HV
Sbjct: 174 CGSPNYTAPEVISGRLYAGPEVDIWSCGVILYALLCGTL-------PFDDE-----HVPT 221
Query: 208 PAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
K+I I EY L + + TL+ LQ+ P KRATI +I
Sbjct: 222 LFKKIRGGVFYIPEY--LNRSVATLLMHMLQVDPLKRATIKDI 262
>EF056019-1|ABK30810.1| 552|Homo sapiens AMP-activated alpha 2
subunit protein.
Length = 552
Score = 79.0 bits (186), Expect = 6e-14
Identities = 66/223 (29%), Positives = 100/223 (44%), Gaps = 23/223 (10%)
Query: 37 SISILGRAQR----LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEEI 92
S+ ++G+ +R L HP++ +I + +V+ V G L D K E
Sbjct: 54 SLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEE 113
Query: 93 INVAR---QVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+ R Q+ + + Y H + + HR L +N+L+D + K+ ++G+ M G +
Sbjct: 114 MEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTS 173
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVND 207
G P Y +PE I GP DIW+ GVIL L G L P HV
Sbjct: 174 CGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTL-------PFDDE-----HVPT 221
Query: 208 PAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
K+I I EY L + + TL+ LQ+ P KRATI +I
Sbjct: 222 LFKKIRGGVFYIPEY--LNRSVATLLMHMLQVDPLKRATIKDI 262
>BC069823-1|AAH69823.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 79.0 bits (186), Expect = 6e-14
Identities = 66/223 (29%), Positives = 100/223 (44%), Gaps = 23/223 (10%)
Query: 37 SISILGRAQR----LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEEI 92
S+ ++G+ +R L HP++ +I + +V+ V G L D K E
Sbjct: 54 SLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEE 113
Query: 93 INVAR---QVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+ R Q+ + + Y H + + HR L +N+L+D + K+ ++G+ M G +
Sbjct: 114 MEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTS 173
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVND 207
G P Y +PE I GP DIW+ GVIL L G L P HV
Sbjct: 174 CGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTL-------PFDDE-----HVPT 221
Query: 208 PAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
K+I I EY L + + TL+ LQ+ P KRATI +I
Sbjct: 222 LFKKIRGGVFYIPEY--LNRSVATLLMHMLQVDPLKRATIKDI 262
>BC069740-1|AAH69740.1| 552|Homo sapiens AMP-activated protein
kinase alpha 2 catalytic subunit protein.
Length = 552
Score = 79.0 bits (186), Expect = 6e-14
Identities = 66/223 (29%), Positives = 100/223 (44%), Gaps = 23/223 (10%)
Query: 37 SISILGRAQR----LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEEI 92
S+ ++G+ +R L HP++ +I + +V+ V G L D K E
Sbjct: 54 SLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEE 113
Query: 93 INVAR---QVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+ R Q+ + + Y H + + HR L +N+L+D + K+ ++G+ M G +
Sbjct: 114 MEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTS 173
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVND 207
G P Y +PE I GP DIW+ GVIL L G L P HV
Sbjct: 174 CGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTL-------PFDDE-----HVPT 221
Query: 208 PAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
K+I I EY L + + TL+ LQ+ P KRATI +I
Sbjct: 222 LFKKIRGGVFYIPEY--LNRSVATLLMHMLQVDPLKRATIKDI 262
>BC069680-1|AAH69680.1| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 79.0 bits (186), Expect = 6e-14
Identities = 66/223 (29%), Positives = 100/223 (44%), Gaps = 23/223 (10%)
Query: 37 SISILGRAQR----LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEEI 92
S+ ++G+ +R L HP++ +I + +V+ V G L D K E
Sbjct: 54 SLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEE 113
Query: 93 INVAR---QVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+ R Q+ + + Y H + + HR L +N+L+D + K+ ++G+ M G +
Sbjct: 114 MEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTS 173
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVND 207
G P Y +PE I GP DIW+ GVIL L G L P HV
Sbjct: 174 CGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTL-------PFDDE-----HVPT 221
Query: 208 PAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
K+I I EY L + + TL+ LQ+ P KRATI +I
Sbjct: 222 LFKKIRGGVFYIPEY--LNRSVATLLMHMLQVDPLKRATIKDI 262
>BC017306-1|AAH17306.1| 628|Homo sapiens NUAK family, SNF1-like
kinase, 2 protein.
Length = 628
Score = 79.0 bits (186), Expect = 6e-14
Identities = 42/143 (29%), Positives = 72/143 (50%), Gaps = 5/143 (3%)
Query: 49 SIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGLQY 105
S+ HP++ ++ + +IV+ L D +++LS E + RQ+ + + Y
Sbjct: 106 SLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHY 165
Query: 106 LHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPETILNS- 164
H N + HR L +NIL+D NG +K+ ++G+ + + G + G P Y SPE +
Sbjct: 166 CHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKP 225
Query: 165 -GGPTADIWTFGVILLELCIGKL 186
GP D W+ GV+L L G +
Sbjct: 226 YTGPEVDSWSLGVLLYILVHGTM 248
>AL035705-2|CAC17574.2| 552|Homo sapiens protein kinase,
AMP-activated, alpha 2 catalytic subunit protein.
Length = 552
Score = 79.0 bits (186), Expect = 6e-14
Identities = 66/223 (29%), Positives = 100/223 (44%), Gaps = 23/223 (10%)
Query: 37 SISILGRAQR----LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEEI 92
S+ ++G+ +R L HP++ +I + +V+ V G L D K E
Sbjct: 54 SLDVVGKIKREIQNLKLFRHPHIIKLYQVISTPTDFFMVMEYVSGGELFDYICKHGRVEE 113
Query: 93 INVAR---QVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+ R Q+ + + Y H + + HR L +N+L+D + K+ ++G+ M G +
Sbjct: 114 MEARRLFQQILSAVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTS 173
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVND 207
G P Y +PE I GP DIW+ GVIL L G L P HV
Sbjct: 174 CGSPNYAAPEVISGRLYAGPEVDIWSCGVILYALLCGTL-------PFDDE-----HVPT 221
Query: 208 PAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
K+I I EY L + + TL+ LQ+ P KRATI +I
Sbjct: 222 LFKKIRGGVFYIPEY--LNRSVATLLMHMLQVDPLKRATIKDI 262
>AK074830-1|BAC11234.1| 628|Homo sapiens protein ( Homo sapiens
cDNA FLJ90349 fis, clone NT2RP2003179, weakly similar to
PUTATIVE SERINE/THREONINE-PROTEIN KINASE EMK (EC
2.7.1.-). ).
Length = 628
Score = 79.0 bits (186), Expect = 6e-14
Identities = 42/143 (29%), Positives = 72/143 (50%), Gaps = 5/143 (3%)
Query: 49 SIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGLQY 105
S+ HP++ ++ + +IV+ L D +++LS E + RQ+ + + Y
Sbjct: 106 SLNHPHIIAIHEVFENSSKIVIVMEYASRGDLYDYISERQQLSEREARHFFRQIVSAVHY 165
Query: 106 LHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPETILNS- 164
H N + HR L +NIL+D NG +K+ ++G+ + + G + G P Y SPE +
Sbjct: 166 CHQNRVVHRDLKLENILLDANGNIKIADFGLSNLYHQGKFLQTFCGSPLYASPEIVNGKP 225
Query: 165 -GGPTADIWTFGVILLELCIGKL 186
GP D W+ GV+L L G +
Sbjct: 226 YTGPEVDSWSLGVLLYILVHGTM 248
>AY120867-1|AAM55491.1| 752|Homo sapiens MAP/microtubule
affinity-regulating kinase-like 1 protein.
Length = 752
Score = 78.6 bits (185), Expect = 8e-14
Identities = 58/227 (25%), Positives = 104/227 (45%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLS-IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L PSS+ L R R++ + HPN+ ++I + +V+ + D ++
Sbjct: 95 LNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMK 154
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + + Y H NI HR L +N+L+D +K+ ++G GS++
Sbjct: 155 EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDT 214
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP DIW+ GVIL L G L P ++
Sbjct: 215 FCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSL-------PFDGH-----NLK 262
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R + Y + ++++ + L + P+KR T+ +I++D
Sbjct: 263 ELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKD 307
>AY057448-1|AAL23683.1| 752|Homo sapiens MARK4 serine/threonine
protein kinase protein.
Length = 752
Score = 78.6 bits (185), Expect = 8e-14
Identities = 58/227 (25%), Positives = 104/227 (45%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLS-IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L PSS+ L R R++ + HPN+ ++I + +V+ + D ++
Sbjct: 95 LNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMK 154
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + + Y H NI HR L +N+L+D +K+ ++G GS++
Sbjct: 155 EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDT 214
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP DIW+ GVIL L G L P ++
Sbjct: 215 FCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSL-------PFDGH-----NLK 262
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R + Y + ++++ + L + P+KR T+ +I++D
Sbjct: 263 ELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKD 307
>AK075272-1|BAC11510.1| 752|Homo sapiens protein ( Homo sapiens
cDNA FLJ90791 fis, clone THYRO1001593, moderately
similar to PUTATIVE SERINE/THREONINE-PROTEIN KINASE P78
(EC 2.7.1.-). ).
Length = 752
Score = 78.6 bits (185), Expect = 8e-14
Identities = 58/227 (25%), Positives = 104/227 (45%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLS-IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L PSS+ L R R++ + HPN+ ++I + +V+ + D ++
Sbjct: 95 LNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMK 154
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + + Y H NI HR L +N+L+D +K+ ++G GS++
Sbjct: 155 EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDT 214
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP DIW+ GVIL L G L P ++
Sbjct: 215 FCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSL-------PFDGH-----NLK 262
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R + Y + ++++ + L + P+KR T+ +I++D
Sbjct: 263 ELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKD 307
>AB088047-1|BAC03375.1| 752|Homo sapiens microtubule
affinity-regulating kinase-like1 protein.
Length = 752
Score = 78.6 bits (185), Expect = 8e-14
Identities = 58/227 (25%), Positives = 104/227 (45%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLS-IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L PSS+ L R R++ + HPN+ ++I + +V+ + D ++
Sbjct: 95 LNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMK 154
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + + Y H NI HR L +N+L+D +K+ ++G GS++
Sbjct: 155 EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDT 214
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP DIW+ GVIL L G L P ++
Sbjct: 215 FCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSL-------PFDGH-----NLK 262
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R + Y + ++++ + L + P+KR T+ +I++D
Sbjct: 263 ELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKD 307
>AB058763-1|BAB47489.1| 689|Homo sapiens KIAA1860 protein protein.
Length = 689
Score = 78.6 bits (185), Expect = 8e-14
Identities = 58/227 (25%), Positives = 104/227 (45%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLS-IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L PSS+ L R R++ + HPN+ ++I + +V+ + D ++
Sbjct: 96 LNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMK 155
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + + Y H NI HR L +N+L+D +K+ ++G GS++
Sbjct: 156 EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDT 215
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP DIW+ GVIL L G L P ++
Sbjct: 216 FCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSL-------PFDGH-----NLK 263
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R + Y + ++++ + L + P+KR T+ +I++D
Sbjct: 264 ELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKD 308
>AB049127-1|BAB39380.1| 688|Homo sapiens MAP/microtubule
affinity-regulating kinase like 1 protein.
Length = 688
Score = 78.6 bits (185), Expect = 8e-14
Identities = 58/227 (25%), Positives = 104/227 (45%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLS-IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L PSS+ L R R++ + HPN+ ++I + +V+ + D ++
Sbjct: 95 LNPSSLQKLFREVRIMKGLNHPNIVKLFEVIETEKTLYLVMEYASAGEVFDYLVSHGRMK 154
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + + Y H NI HR L +N+L+D +K+ ++G GS++
Sbjct: 155 EKEARAKFRQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDT 214
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP DIW+ GVIL L G L P ++
Sbjct: 215 FCGSPPYAAPELFQGKKYDGPEVDIWSLGVILYTLVSGSL-------PFDGH-----NLK 262
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R + Y + ++++ + L + P+KR T+ +I++D
Sbjct: 263 ELRERVLRGKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKD 307
>X97630-1|CAA66229.1| 745|Homo sapiens serine/threonine protein
kinase protein.
Length = 745
Score = 78.2 bits (184), Expect = 1e-13
Identities = 60/227 (26%), Positives = 106/227 (46%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L SS+ L R R++ + HPN+ ++I + +V+ G + D ++
Sbjct: 56 LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK 115
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + +QY H I HR L +N+L+D + +K+ ++G G+++
Sbjct: 116 EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDT 175
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 176 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NLK 223
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L++K L + PSKR T+ +I++D
Sbjct: 224 ELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKD 268
>BT007342-1|AAP36006.1| 755|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 755
Score = 78.2 bits (184), Expect = 1e-13
Identities = 60/227 (26%), Positives = 106/227 (46%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L SS+ L R R++ + HPN+ ++I + +V+ G + D ++
Sbjct: 56 LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK 115
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + +QY H I HR L +N+L+D + +K+ ++G G+++
Sbjct: 116 EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDT 175
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 176 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NLK 223
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L++K L + PSKR T+ +I++D
Sbjct: 224 ELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKD 268
>BC084540-1|AAH84540.1| 724|Homo sapiens MAP/microtubule
affinity-regulating kinase 2 protein.
Length = 724
Score = 78.2 bits (184), Expect = 1e-13
Identities = 60/227 (26%), Positives = 106/227 (46%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L SS+ L R R++ + HPN+ ++I + +V+ G + D ++
Sbjct: 89 LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK 148
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + +QY H I HR L +N+L+D + +K+ ++G G+++
Sbjct: 149 EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDT 208
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 209 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NLK 256
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L++K L + PSKR T+ +I++D
Sbjct: 257 ELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKD 301
>BC008771-1|AAH08771.2| 778|Homo sapiens MARK2 protein protein.
Length = 778
Score = 78.2 bits (184), Expect = 1e-13
Identities = 60/227 (26%), Positives = 106/227 (46%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L SS+ L R R++ + HPN+ ++I + +V+ G + D ++
Sbjct: 79 LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK 138
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + +QY H I HR L +N+L+D + +K+ ++G G+++
Sbjct: 139 EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDT 198
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 199 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NLK 246
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L++K L + PSKR T+ +I++D
Sbjct: 247 ELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKD 291
>AL591849-3|CAI40161.1| 1178|Homo sapiens novel protein protein.
Length = 1178
Score = 78.2 bits (184), Expect = 1e-13
Identities = 58/211 (27%), Positives = 98/211 (46%), Gaps = 10/211 (4%)
Query: 409 IPPLVRGDVWAALLGVVGDIE---EQYERIDKE---TPTPTDRQIDVDIPRCHQYCWLLC 462
IP +RG++W G V D+ + Y + ++ T +I+ D+ R
Sbjct: 546 IPETLRGELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQ 605
Query: 463 GSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHK 522
G L+R+L A+ NP+ Y Q ++ LT+ + L + E AF L A + L
Sbjct: 606 SDTGISALRRVLTAYAYRNPKIGYCQAMNILTS--VLLLYAKEEEAFWLLVAVCERMLPD 663
Query: 523 FFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLHKI 582
+F + + + A F ++ H P+L H+ D+ F + ++ WFLT+F V P+
Sbjct: 664 YFNRRIIGALVDQ-AVFEELIRDHLPQLTEHMTDMTFFSSV-SLSWFLTLFISVLPIESA 721
Query: 583 VHLWDAFLVEGPSLPLFMGVGILRQLRDTLL 613
V++ D F +G L +G+ IL D LL
Sbjct: 722 VNVVDCFFYDGIKAILQLGLAILDYNLDKLL 752
>AL391315-4|CAI39548.1| 1178|Homo sapiens novel protein protein.
Length = 1178
Score = 78.2 bits (184), Expect = 1e-13
Identities = 58/211 (27%), Positives = 98/211 (46%), Gaps = 10/211 (4%)
Query: 409 IPPLVRGDVWAALLGVVGDIE---EQYERIDKE---TPTPTDRQIDVDIPRCHQYCWLLC 462
IP +RG++W G V D+ + Y + ++ T +I+ D+ R
Sbjct: 546 IPETLRGELWMLFSGAVNDMATNPDYYTEVVEQSLGTCNLATEEIERDLRRSLPEHPAFQ 605
Query: 463 GSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHK 522
G L+R+L A+ NP+ Y Q ++ LT+ + L + E AF L A + L
Sbjct: 606 SDTGISALRRVLTAYAYRNPKIGYCQAMNILTS--VLLLYAKEEEAFWLLVAVCERMLPD 663
Query: 523 FFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLHKI 582
+F + + + A F ++ H P+L H+ D+ F + ++ WFLT+F V P+
Sbjct: 664 YFNRRIIGALVDQ-AVFEELIRDHLPQLTEHMTDMTFFSSV-SLSWFLTLFISVLPIESA 721
Query: 583 VHLWDAFLVEGPSLPLFMGVGILRQLRDTLL 613
V++ D F +G L +G+ IL D LL
Sbjct: 722 VNVVDCFFYDGIKAILQLGLAILDYNLDKLL 752
>AF387638-1|AAK82368.1| 691|Homo sapiens Ser/Thr protein kinase
PAR-1Balpha protein.
Length = 691
Score = 78.2 bits (184), Expect = 1e-13
Identities = 60/227 (26%), Positives = 106/227 (46%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L SS+ L R R++ + HPN+ ++I + +V+ G + D ++
Sbjct: 56 LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK 115
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + +QY H I HR L +N+L+D + +K+ ++G G+++
Sbjct: 116 EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDT 175
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 176 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NLK 223
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L++K L + PSKR T+ +I++D
Sbjct: 224 ELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKD 268
>AB188493-1|BAD37141.1| 719|Homo sapiens serine/threonine kinase
protein.
Length = 719
Score = 78.2 bits (184), Expect = 1e-13
Identities = 60/227 (26%), Positives = 106/227 (46%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L SS+ L R R++ + HPN+ ++I + +V+ G + D ++
Sbjct: 89 LNSSSLQKLFREVRIMKVLNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK 148
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + +QY H I HR L +N+L+D + +K+ ++G G+++
Sbjct: 149 EKEARAKFRQIVSAVQYCHQKFIVHRDLKAENLLLDADMNIKIADFGFSNEFTFGNKLDT 208
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 209 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NLK 256
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L++K L + PSKR T+ +I++D
Sbjct: 257 ELRERVLRGKYRIPFY--MSTDCENLLKKFLILNPSKRGTLEQIMKD 301
>BC037303-1|AAH37303.1| 550|Homo sapiens PRKAA1 protein protein.
Length = 550
Score = 77.8 bits (183), Expect = 1e-13
Identities = 46/159 (28%), Positives = 77/159 (48%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQR----LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S+ ++G+ +R L HP++ +I + +V+ V G L D +L
Sbjct: 56 SLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDE 115
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E + +Q+ +G+ Y H + + HR L +N+L+D + K+ ++G+ M G +
Sbjct: 116 KESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTS 175
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y +PE I GP DIW+ GVIL L G L
Sbjct: 176 CGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTL 214
>AB022017-1|BAA36547.1| 550|Homo sapiens AMP-activated protein
kinase alpha-1 protein.
Length = 550
Score = 77.8 bits (183), Expect = 1e-13
Identities = 46/159 (28%), Positives = 77/159 (48%), Gaps = 9/159 (5%)
Query: 37 SISILGRAQR----LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLST 89
S+ ++G+ +R L HP++ +I + +V+ V G L D +L
Sbjct: 56 SLDVVGKIRREIQNLKLFRHPHIIKLYQVISTPSDIFMVMEYVSGGELFDYICKNGRLDE 115
Query: 90 EEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP 149
+E + +Q+ +G+ Y H + + HR L +N+L+D + K+ ++G+ M G +
Sbjct: 116 KESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGEFLRTS 175
Query: 150 LGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
G P Y +PE I GP DIW+ GVIL L G L
Sbjct: 176 CGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTL 214
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I+HPN+ T ++ K + I+++ V G L D K+ L+ EE +Q+ NG+
Sbjct: 68 LKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++K+ ++G+ + G+E G P +++PE
Sbjct: 128 YYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I+HPN+ T ++ K + I+++ V G L D K+ L+ EE +Q+ NG+
Sbjct: 68 LKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++K+ ++G+ + G+E G P +++PE
Sbjct: 128 YYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>BT006935-1|AAP35581.1| 367|Homo sapiens death-associated protein
kinase 1 protein.
Length = 367
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I+HPN+ T ++ K + I+++ V G L D K+ L+ EE +Q+ NG+
Sbjct: 68 LKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++K+ ++G+ + G+E G P +++PE
Sbjct: 128 YYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I+HPN+ T ++ K + I+++ V G L D K+ L+ EE +Q+ NG+
Sbjct: 68 LKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++K+ ++G+ + G+E G P +++PE
Sbjct: 128 YYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I+HPN+ T ++ K + I+++ V G L D K+ L+ EE +Q+ NG+
Sbjct: 68 LKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++K+ ++G+ + G+E G P +++PE
Sbjct: 128 YYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I+HPN+ T ++ K + I+++ V G L D K+ L+ EE +Q+ NG+
Sbjct: 68 LKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++K+ ++G+ + G+E G P +++PE
Sbjct: 128 YYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I+HPN+ T ++ K + I+++ V G L D K+ L+ EE +Q+ NG+
Sbjct: 68 LKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGV 127
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++K+ ++G+ + G+E G P +++PE
Sbjct: 128 YYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPE 187
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 188 IVNYEPLGLEADMWSIGVITYILLSG 213
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 77.4 bits (182), Expect = 2e-13
Identities = 47/146 (32%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L I+HPN+ T ++ K + I+++ V G L D K+ L+ EE +Q+ NG+
Sbjct: 71 LKEIQHPNVITLHEVYENKTDVILILELVAGGELFDFLAEKESLTEEEATEFLKQILNGV 130
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH+ I H L +NI L+D N ++K+ ++G+ + G+E G P +++PE
Sbjct: 131 YYLHSLQIAHFDLKPENIMLLDRNVPKPRIKIIDFGLAHKIDFGNEFKNIFGTPEFVAPE 190
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 191 IVNYEPLGLEADMWSIGVITYILLSG 216
>AB209428-1|BAD92665.1| 279|Homo sapiens p21-activated kinase 2
variant protein.
Length = 279
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/225 (26%), Positives = 107/225 (47%), Gaps = 20/225 (8%)
Query: 35 PSSISILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKLSTEE--I 92
P I+ + +++PN+ +LD E +VV + SL D+ + +E I
Sbjct: 44 PKKELIINEILVMKELKNPNIVNFLDSYLVGDELFVVVEYLARGSLTDVVTETCMDEAQI 103
Query: 93 INVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGI-FYMTYGGSEVAFPLG 151
V R+ L++LHAN + HR + D++L+ + G VKL ++G +T S+ + +
Sbjct: 104 AAVCRESLQALEFLHANQVIHRDIKSDSVLLGMEGSVKLTDFGFCAQITPEQSKRSTVIR 163
Query: 152 QPRYLSPETILNSG-GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAK 210
P +++PE + GP ++W+ G++ E+ G+ L P+ R L L+
Sbjct: 164 TPYWMAPEVVTRKAYGPKVNVWSLGIMATEMVEGEP-PYLNENPL--RALCLIAT----- 215
Query: 211 RIAREHNSIEEYEQLPKYLQTLI-EKCLQICPSKRATITEILQDL 254
N I E Q P+ L + ++CL+ KR + E+LQ L
Sbjct: 216 ------NGIPEL-QNPETLSPIFRDRCLETDVEKRGSAKELLQHL 253
>Y11950-1|CAA72694.1| 406|Homo sapiens phosphorylase kinase gamma
subunit protein.
Length = 406
Score = 76.6 bits (180), Expect = 3e-13
Identities = 78/281 (27%), Positives = 118/281 (41%), Gaps = 28/281 (9%)
Query: 52 HPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGLQYLHA 108
HP++ T +D +V + L D K LS +E ++ R + + +LHA
Sbjct: 87 HPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHA 146
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPETILNS---- 164
NNI HR L +NIL+D N +++L ++G G ++ G P YL+PE + S
Sbjct: 147 NNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDET 206
Query: 165 ---GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEE 221
G D+W GVIL L G P R+IL L + + + S E
Sbjct: 207 HPGYGKEVDLWACGVILFTLLAGS-----PPFWHRRQILMLRMIME-----GQYQFSSPE 256
Query: 222 YEQLPKYLQTLIEKCLQICPSKRATITEILQDLSNVDTKEMCAVKPPRGLMGCKLQYLYH 281
++ ++ LI + LQ+ P R T + LQ E C P L + +
Sbjct: 257 WDDRSSTVKDLISRLLQVDPEARLTAEQALQH----PFFERCEGSQPWNLTPRQRFRVAV 312
Query: 282 WWQLAGGDIQVELKR-NGLIKNS---PPILSIPVAILLDGC 318
W LA G + + R L KN+ P V L+D C
Sbjct: 313 WTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNC 353
>M31606-1|AAA36442.1| 406|Homo sapiens phosphorylase kinase
protein.
Length = 406
Score = 76.6 bits (180), Expect = 3e-13
Identities = 78/281 (27%), Positives = 118/281 (41%), Gaps = 28/281 (9%)
Query: 52 HPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGLQYLHA 108
HP++ T +D +V + L D K LS +E ++ R + + +LHA
Sbjct: 87 HPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHA 146
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPETILNS---- 164
NNI HR L +NIL+D N +++L ++G G ++ G P YL+PE + S
Sbjct: 147 NNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDET 206
Query: 165 ---GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEE 221
G D+W GVIL L G P R+IL L + + + S E
Sbjct: 207 HPGYGKEVDLWACGVILFTLLAGS-----PPFWHRRQILMLRMIME-----GQYQFSSPE 256
Query: 222 YEQLPKYLQTLIEKCLQICPSKRATITEILQDLSNVDTKEMCAVKPPRGLMGCKLQYLYH 281
++ ++ LI + LQ+ P R T + LQ E C P L + +
Sbjct: 257 WDDRSSTVKDLISRLLQVDPEARLTAEQALQH----PFFERCEGSQPWNLTPRQRFRVAV 312
Query: 282 WWQLAGGDIQVELKR-NGLIKNS---PPILSIPVAILLDGC 318
W LA G + + R L KN+ P V L+D C
Sbjct: 313 WTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNC 353
>BC114478-1|AAI14479.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 76.6 bits (180), Expect = 3e-13
Identities = 59/227 (25%), Positives = 106/227 (46%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L P+S+ L R R++ I HPN+ ++I + +V+ G + D ++
Sbjct: 96 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK 155
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + +QY H I HR L +N+L+D + +K+ ++G G+++
Sbjct: 156 EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDT 215
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 216 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NLK 263
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L++K L + P KR ++ +I++D
Sbjct: 264 ELRERVLRGKYRIPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKD 308
>BC113869-1|AAI13870.1| 795|Homo sapiens MARK1 protein protein.
Length = 795
Score = 76.6 bits (180), Expect = 3e-13
Identities = 59/227 (25%), Positives = 106/227 (46%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L P+S+ L R R++ I HPN+ ++I + +V+ G + D ++
Sbjct: 96 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK 155
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + +QY H I HR L +N+L+D + +K+ ++G G+++
Sbjct: 156 EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDT 215
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 216 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NLK 263
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L++K L + P KR ++ +I++D
Sbjct: 264 ELRERVLRGKYRIPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKD 308
>BC002541-1|AAH02541.1| 406|Homo sapiens phosphorylase kinase,
gamma 2 (testis) protein.
Length = 406
Score = 76.6 bits (180), Expect = 3e-13
Identities = 78/281 (27%), Positives = 118/281 (41%), Gaps = 28/281 (9%)
Query: 52 HPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGLQYLHA 108
HP++ T +D +V + L D K LS +E ++ R + + +LHA
Sbjct: 87 HPHIITLIDSYESSSFMFLVFDLMRKGELFDYLTEKVALSEKETRSIMRSLLEAVSFLHA 146
Query: 109 NNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPETILNS---- 164
NNI HR L +NIL+D N +++L ++G G ++ G P YL+PE + S
Sbjct: 147 NNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYLAPEILKCSMDET 206
Query: 165 ---GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEE 221
G D+W GVIL L G P R+IL L + + + S E
Sbjct: 207 HPGYGKEVDLWACGVILFTLLAGS-----PPFWHRRQILMLRMIME-----GQYQFSSPE 256
Query: 222 YEQLPKYLQTLIEKCLQICPSKRATITEILQDLSNVDTKEMCAVKPPRGLMGCKLQYLYH 281
++ ++ LI + LQ+ P R T + LQ E C P L + +
Sbjct: 257 WDDRSSTVKDLISRLLQVDPEARLTAEQALQH----PFFERCEGSQPWNLTPRQRFRVAV 312
Query: 282 WWQLAGGDIQVELKR-NGLIKNS---PPILSIPVAILLDGC 318
W LA G + + R L KN+ P V L+D C
Sbjct: 313 WTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNC 353
>AL592406-3|CAH72463.1| 795|Homo sapiens MAP/microtubule
affinity-regulating kinase 1 protein.
Length = 795
Score = 76.6 bits (180), Expect = 3e-13
Identities = 59/227 (25%), Positives = 106/227 (46%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L P+S+ L R R++ I HPN+ ++I + +V+ G + D ++
Sbjct: 96 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK 155
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + +QY H I HR L +N+L+D + +K+ ++G G+++
Sbjct: 156 EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDT 215
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 216 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NLK 263
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L++K L + P KR ++ +I++D
Sbjct: 264 ELRERVLRGKYRIPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKD 308
>AF154845-1|AAF72103.1| 795|Homo sapiens MARK protein.
Length = 795
Score = 76.6 bits (180), Expect = 3e-13
Identities = 59/227 (25%), Positives = 106/227 (46%), Gaps = 20/227 (8%)
Query: 33 LTPSSISILGRAQRLLSI-EHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLS 88
L P+S+ L R R++ I HPN+ ++I + +V+ G + D ++
Sbjct: 96 LNPTSLQKLFREVRIMKILNHPNIVKLFEVIETEKTLYLVMEYASGGEVFDYLVAHGRMK 155
Query: 89 TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAF 148
+E RQ+ + +QY H I HR L +N+L+D + +K+ ++G G+++
Sbjct: 156 EKEARAKFRQIVSAVQYCHQKYIVHRDLKAENLLLDGDMNIKIADFGFSNEFTVGNKLDT 215
Query: 149 PLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVN 206
G P Y +PE GP D+W+ GVIL L G L P + ++
Sbjct: 216 FCGSPPYAAPELFQGKKYDGPEVDVWSLGVILYTLVSGSL-------PFDGQ-----NLK 263
Query: 207 DPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ +R+ R I Y + + L++K L + P KR ++ +I++D
Sbjct: 264 ELRERVLRGKYRIPFY--MSTDCENLLKKLLVLNPIKRGSLEQIMKD 308
>AL355341-2|CAH70583.2| 775|Homo sapiens TBC1 domain family, member
12 protein.
Length = 775
Score = 76.2 bits (179), Expect = 4e-13
Identities = 78/336 (23%), Positives = 135/336 (40%), Gaps = 32/336 (9%)
Query: 324 TGVLYDRRIAKYSIELLQSRLSHVSAHDYYPLMHERKKQNDAVTLPKTIRER---DTEYQ 380
T ++ + R + + ++ L H +D ++++ +A + ++ER +
Sbjct: 395 TALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEENIA 454
Query: 381 FYRLLWFQRLLHGYPY--TAPYIRAEAEIDIPPLVRGDVWAALLGVVGDIE-EQYERI-- 435
++W +L + + +R +PP VRG VW+ +G +I E YE
Sbjct: 455 SAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLS 514
Query: 436 ----------------DKETPTPTDRQ-----IDVDIPRCHQYCWLLC-GSAGHRTLKRL 473
D E + DR+ I +DI R ++ G H L +
Sbjct: 515 RAKERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSI 574
Query: 474 LKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKFFLKDNSAVIK 533
L A+ P Y QG+ S A + LN EA AF + + K F + + +++
Sbjct: 575 LGAYTCYRPDVGYVQGM-SFIAAVLILNL-EEADAFIAFANLLNKPCQLAFFRVDHSMML 632
Query: 534 EYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLHKIVHLWDAFLVEG 593
+Y A F + +L H + P+++ I W T++S PL +WD F +G
Sbjct: 633 KYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDG 692
Query: 594 PSLPLFMGVGILRQLRDTLLESGFNECILLFSDLPE 629
G+GILR D LL+ F + LPE
Sbjct: 693 EEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPE 728
>AL138759-3|CAH70223.2| 775|Homo sapiens TBC1 domain family, member
12 protein.
Length = 775
Score = 76.2 bits (179), Expect = 4e-13
Identities = 78/336 (23%), Positives = 135/336 (40%), Gaps = 32/336 (9%)
Query: 324 TGVLYDRRIAKYSIELLQSRLSHVSAHDYYPLMHERKKQNDAVTLPKTIRER---DTEYQ 380
T ++ + R + + ++ L H +D ++++ +A + ++ER +
Sbjct: 395 TALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEENIA 454
Query: 381 FYRLLWFQRLLHGYPY--TAPYIRAEAEIDIPPLVRGDVWAALLGVVGDIE-EQYERI-- 435
++W +L + + +R +PP VRG VW+ +G +I E YE
Sbjct: 455 SAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLS 514
Query: 436 ----------------DKETPTPTDRQ-----IDVDIPRCHQYCWLLC-GSAGHRTLKRL 473
D E + DR+ I +DI R ++ G H L +
Sbjct: 515 RAKERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSI 574
Query: 474 LKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKFFLKDNSAVIK 533
L A+ P Y QG+ S A + LN EA AF + + K F + + +++
Sbjct: 575 LGAYTCYRPDVGYVQGM-SFIAAVLILNL-EEADAFIAFANLLNKPCQLAFFRVDHSMML 632
Query: 534 EYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLHKIVHLWDAFLVEG 593
+Y A F + +L H + P+++ I W T++S PL +WD F +G
Sbjct: 633 KYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDG 692
Query: 594 PSLPLFMGVGILRQLRDTLLESGFNECILLFSDLPE 629
G+GILR D LL+ F + LPE
Sbjct: 693 EEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPE 728
>AB011180-1|BAA25534.1| 775|Homo sapiens KIAA0608 protein protein.
Length = 775
Score = 76.2 bits (179), Expect = 4e-13
Identities = 78/336 (23%), Positives = 135/336 (40%), Gaps = 32/336 (9%)
Query: 324 TGVLYDRRIAKYSIELLQSRLSHVSAHDYYPLMHERKKQNDAVTLPKTIRER---DTEYQ 380
T ++ + R + + ++ L H +D ++++ +A + ++ER +
Sbjct: 395 TALILEDRPSNLPAKSVEEALRHRQEYDEMVAEAKKREIKEAHKRKRIMKERFKQEENIA 454
Query: 381 FYRLLWFQRLLHGYPY--TAPYIRAEAEIDIPPLVRGDVWAALLGVVGDIE-EQYERI-- 435
++W +L + + +R +PP VRG VW+ +G +I E YE
Sbjct: 455 SAMVIWINEILPNWEVMRSTRRVRELWWQGLPPSVRGKVWSLAVGNELNITPELYEIFLS 514
Query: 436 ----------------DKETPTPTDRQ-----IDVDIPRCHQYCWLLC-GSAGHRTLKRL 473
D E + DR+ I +DI R ++ G H L +
Sbjct: 515 RAKERWKSFSETSSENDTEGVSVADREASLELIKLDISRTFPSLYIFQKGGPYHDVLHSI 574
Query: 474 LKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKFFLKDNSAVIK 533
L A+ P Y QG+ S A + LN EA AF + + K F + + +++
Sbjct: 575 LGAYTCYRPDVGYVQGM-SFIAAVLILNL-EEADAFIAFANLLNKPCQLAFFRVDHSMML 632
Query: 534 EYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLHKIVHLWDAFLVEG 593
+Y A F + +L H + P+++ I W T++S PL +WD F +G
Sbjct: 633 KYFATFEVFFEENLSKLFLHFKSYSLTPDIYLIDWIFTLYSKSLPLDLACRVWDVFCRDG 692
Query: 594 PSLPLFMGVGILRQLRDTLLESGFNECILLFSDLPE 629
G+GILR D LL+ F + LPE
Sbjct: 693 EEFLFRTGLGILRLYEDILLQMDFIHIAQFLTKLPE 728
>AB011109-1|BAA25463.2| 698|Homo sapiens KIAA0537 protein protein.
Length = 698
Score = 76.2 bits (179), Expect = 4e-13
Identities = 61/210 (29%), Positives = 99/210 (47%), Gaps = 26/210 (12%)
Query: 49 SIEHPNLCTYLDIIRGKHERIIVVAEVIGKS-LADL---KKKLSTEEIINVARQVANGLQ 104
S+ HP++ + ++ K ++I+++ E K L D +++LS E + RQ+ + +
Sbjct: 146 SLNHPHIISIYEVFENK-DKIVIIMEYASKGELYDYISERRRLSERETRHFFRQIVSAVH 204
Query: 105 YLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPETILNS 164
Y H N + HR L +NIL+D N +K+ ++G+ + + G P Y SPE I+N
Sbjct: 205 YCHKNGVVHRDLKLENILLDDNCNIKIADFGLSNLYQKDKFLQTFCGSPLYASPE-IVNG 263
Query: 165 ---GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEE 221
GP D W GV+L L G + G H K + R+ +S E
Sbjct: 264 RPYRGPEVDSWALGVLLYTLVYGTM-----------PFDGFDH-----KNLIRQISSGEY 307
Query: 222 YEQL-PKYLQTLIEKCLQICPSKRATITEI 250
E P + LI L + P +RATI +I
Sbjct: 308 REPTQPSDARGLIRWMLMVNPDRRATIEDI 337
>BC133039-1|AAI33040.1| 1001|Homo sapiens TAO kinase 1 protein.
Length = 1001
Score = 74.5 bits (175), Expect = 1e-12
Identities = 61/223 (27%), Positives = 102/223 (45%), Gaps = 24/223 (10%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
I+ + L I+HPN Y +H +V+ +G S +DL KK L EI +
Sbjct: 73 IIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 131
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
GL YLH++ + HR + NIL+ G+VKL ++G M + +G P +
Sbjct: 132 THGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF---VGTPYW 188
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G D+W+ G+ +EL A+ KP P+ ++
Sbjct: 189 MAPEVILAMDEGQYDGKVDVWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 236
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQDL 254
IA+ + + + Y + ++ CLQ P R T E+L+ +
Sbjct: 237 IAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHI 279
>BC026158-1|AAH26158.1| 1315|Homo sapiens serine/threonine kinase
36, fused homolog (Drosophila) protein.
Length = 1315
Score = 74.5 bits (175), Expect = 1e-12
Identities = 44/139 (31%), Positives = 70/139 (50%), Gaps = 4/139 (2%)
Query: 50 IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKK--KLSTEEIINVARQVANGLQYLH 107
+ HPN+ LD E ++V G+ L+ KL +++ +A Q+ + L YLH
Sbjct: 58 LRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLH 117
Query: 108 ANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPL-GQPRYLSPETILNSG- 165
++ I HR + NIL+ G +KL ++G + V + G P Y+SPE +
Sbjct: 118 SHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPY 177
Query: 166 GPTADIWTFGVILLELCIG 184
TAD+W+ G IL EL +G
Sbjct: 178 DHTADLWSVGCILYELAVG 196
>AY049015-1|AAL12217.1| 1001|Homo sapiens serine/threonine kinase
TAO1 protein.
Length = 1001
Score = 74.5 bits (175), Expect = 1e-12
Identities = 61/223 (27%), Positives = 102/223 (45%), Gaps = 24/223 (10%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
I+ + L I+HPN Y +H +V+ +G S +DL KK L EI +
Sbjct: 73 IIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 131
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
GL YLH++ + HR + NIL+ G+VKL ++G M + +G P +
Sbjct: 132 THGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF---VGTPYW 188
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G D+W+ G+ +EL A+ KP P+ ++
Sbjct: 189 MAPEVILAMDEGQYDGKVDVWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 236
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQDL 254
IA+ + + + Y + ++ CLQ P R T E+L+ +
Sbjct: 237 IAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHI 279
>AF200815-1|AAF97028.1| 1315|Homo sapiens FUSED serine/threonine
kinase protein.
Length = 1315
Score = 74.5 bits (175), Expect = 1e-12
Identities = 44/139 (31%), Positives = 70/139 (50%), Gaps = 4/139 (2%)
Query: 50 IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKK--KLSTEEIINVARQVANGLQYLH 107
+ HPN+ LD E ++V G+ L+ KL +++ +A Q+ + L YLH
Sbjct: 58 LRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLH 117
Query: 108 ANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPL-GQPRYLSPETILNSG- 165
++ I HR + NIL+ G +KL ++G + V + G P Y+SPE +
Sbjct: 118 SHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPY 177
Query: 166 GPTADIWTFGVILLELCIG 184
TAD+W+ G IL EL +G
Sbjct: 178 DHTADLWSVGCILYELAVG 196
>AB037782-1|BAA92599.1| 1005|Homo sapiens KIAA1361 protein protein.
Length = 1005
Score = 74.5 bits (175), Expect = 1e-12
Identities = 61/223 (27%), Positives = 102/223 (45%), Gaps = 24/223 (10%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
I+ + L I+HPN Y +H +V+ +G S +DL KK L EI +
Sbjct: 77 IIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 135
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
GL YLH++ + HR + NIL+ G+VKL ++G M + +G P +
Sbjct: 136 THGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF---VGTPYW 192
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G D+W+ G+ +EL A+ KP P+ ++
Sbjct: 193 MAPEVILAMDEGQYDGKVDVWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 240
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQDL 254
IA+ + + + Y + ++ CLQ P R T E+L+ +
Sbjct: 241 IAQNESPTLQSNEWSDYFRNFVDSCLQKIPQDRPTSEELLKHI 283
>AB033104-1|BAA86592.1| 1311|Homo sapiens KIAA1278 protein protein.
Length = 1311
Score = 74.5 bits (175), Expect = 1e-12
Identities = 44/139 (31%), Positives = 70/139 (50%), Gaps = 4/139 (2%)
Query: 50 IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKK--KLSTEEIINVARQVANGLQYLH 107
+ HPN+ LD E ++V G+ L+ KL +++ +A Q+ + L YLH
Sbjct: 75 LRHPNIVHMLDSFETDKEVVVVTDYAEGELFQILEDDGKLPEDQVQAIAAQLVSALYYLH 134
Query: 108 ANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPL-GQPRYLSPETILNSG- 165
++ I HR + NIL+ G +KL ++G + V + G P Y+SPE +
Sbjct: 135 SHRILHRDMKPQNILLAKGGGIKLCDFGFARAMSTNTMVLTSIKGTPLYMSPELVEERPY 194
Query: 166 GPTADIWTFGVILLELCIG 184
TAD+W+ G IL EL +G
Sbjct: 195 DHTADLWSVGCILYELAVG 213
>AF263312-1|AAG38502.1| 1001|Homo sapiens STE20-like kinase protein.
Length = 1001
Score = 73.7 bits (173), Expect = 2e-12
Identities = 61/223 (27%), Positives = 102/223 (45%), Gaps = 24/223 (10%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
I+ + L I+HPN Y +H +V+ +G S +DL KK L EI +
Sbjct: 73 IIKEVKFLQRIKHPNSIEYKGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 131
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
GL YLH++ + HR + NIL+ G+VKL ++G M + +G P +
Sbjct: 132 THGALQGLAYLHSHTMIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF---VGTPYW 188
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G D+W+ G+ +EL A+ KP P+ ++
Sbjct: 189 MAPEVILAMDEGQYDGKVDVWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 236
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQDL 254
IA+ + + + Y + ++ CLQ P R T E+L+ +
Sbjct: 237 IAQNESPTLQSNEWSDYFRNSVDSCLQKIPQDRPTSEELLKHI 279
>U78876-1|AAB41729.1| 626|Homo sapiens MEK kinase 3 protein.
Length = 626
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/170 (30%), Positives = 83/170 (48%), Gaps = 12/170 (7%)
Query: 32 PLTPSSISILG-RAQRLLSIEHPNLCTYLDIIRGKHERIIVV--AEVIGKSLADLKKKLS 88
P T +S L Q L +++H + Y +R + E+ + + + G S+ D K
Sbjct: 400 PETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYG 459
Query: 89 --TEEIIN-VARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYG----IFYMTY 141
TE + RQ+ G+ YLH+N I HR + NIL D G VKL ++G + +
Sbjct: 460 ALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM 519
Query: 142 GGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILLELCIGK-LWAK 189
G+ + G P ++SPE I G G AD+W+ G ++E+ K WA+
Sbjct: 520 SGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE 569
>DQ454151-1|ABE11554.1| 622|Homo sapiens mitogen-activated protein
kinase kinase kinase 3 variant 2 protein.
Length = 622
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/170 (30%), Positives = 83/170 (48%), Gaps = 12/170 (7%)
Query: 32 PLTPSSISILG-RAQRLLSIEHPNLCTYLDIIRGKHERIIVV--AEVIGKSLADLKKKLS 88
P T +S L Q L +++H + Y +R + E+ + + + G S+ D K
Sbjct: 396 PETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYG 455
Query: 89 --TEEIIN-VARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYG----IFYMTY 141
TE + RQ+ G+ YLH+N I HR + NIL D G VKL ++G + +
Sbjct: 456 ALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM 515
Query: 142 GGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILLELCIGK-LWAK 189
G+ + G P ++SPE I G G AD+W+ G ++E+ K WA+
Sbjct: 516 SGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE 565
>BC093674-1|AAH93674.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3, isoform 2 protein.
Length = 626
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/170 (30%), Positives = 83/170 (48%), Gaps = 12/170 (7%)
Query: 32 PLTPSSISILG-RAQRLLSIEHPNLCTYLDIIRGKHERIIVV--AEVIGKSLADLKKKLS 88
P T +S L Q L +++H + Y +R + E+ + + + G S+ D K
Sbjct: 400 PETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYG 459
Query: 89 --TEEIIN-VARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYG----IFYMTY 141
TE + RQ+ G+ YLH+N I HR + NIL D G VKL ++G + +
Sbjct: 460 ALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM 519
Query: 142 GGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILLELCIGK-LWAK 189
G+ + G P ++SPE I G G AD+W+ G ++E+ K WA+
Sbjct: 520 SGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE 569
>BC093672-1|AAH93672.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3, isoform 2 protein.
Length = 626
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/170 (30%), Positives = 83/170 (48%), Gaps = 12/170 (7%)
Query: 32 PLTPSSISILG-RAQRLLSIEHPNLCTYLDIIRGKHERIIVV--AEVIGKSLADLKKKLS 88
P T +S L Q L +++H + Y +R + E+ + + + G S+ D K
Sbjct: 400 PETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYG 459
Query: 89 --TEEIIN-VARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYG----IFYMTY 141
TE + RQ+ G+ YLH+N I HR + NIL D G VKL ++G + +
Sbjct: 460 ALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM 519
Query: 142 GGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILLELCIGK-LWAK 189
G+ + G P ++SPE I G G AD+W+ G ++E+ K WA+
Sbjct: 520 SGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE 569
>BC090859-1|AAH90859.1| 626|Homo sapiens mitogen-activated protein
kinase kinase kinase 3 protein.
Length = 626
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/170 (30%), Positives = 83/170 (48%), Gaps = 12/170 (7%)
Query: 32 PLTPSSISILG-RAQRLLSIEHPNLCTYLDIIRGKHERIIVV--AEVIGKSLADLKKKLS 88
P T +S L Q L +++H + Y +R + E+ + + + G S+ D K
Sbjct: 400 PETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYG 459
Query: 89 --TEEIIN-VARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYG----IFYMTY 141
TE + RQ+ G+ YLH+N I HR + NIL D G VKL ++G + +
Sbjct: 460 ALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM 519
Query: 142 GGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILLELCIGK-LWAK 189
G+ + G P ++SPE I G G AD+W+ G ++E+ K WA+
Sbjct: 520 SGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE 569
>BC008336-1|AAH08336.1| 594|Homo sapiens Unknown (protein for
IMAGE:3506235) protein.
Length = 594
Score = 73.3 bits (172), Expect = 3e-12
Identities = 52/170 (30%), Positives = 83/170 (48%), Gaps = 12/170 (7%)
Query: 32 PLTPSSISILG-RAQRLLSIEHPNLCTYLDIIRGKHERIIVV--AEVIGKSLADLKKKLS 88
P T +S L Q L +++H + Y +R + E+ + + + G S+ D K
Sbjct: 368 PETSKEVSALECEIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYG 427
Query: 89 --TEEIIN-VARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYG----IFYMTY 141
TE + RQ+ G+ YLH+N I HR + NIL D G VKL ++G + +
Sbjct: 428 ALTESVTRKYTRQILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICM 487
Query: 142 GGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILLELCIGK-LWAK 189
G+ + G P ++SPE I G G AD+W+ G ++E+ K WA+
Sbjct: 488 SGTGMRSVTGTPYWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAE 537
>BC041167-1|AAH41167.1| 678|Homo sapiens TBC1 domain family, member
14 protein.
Length = 678
Score = 72.9 bits (171), Expect = 4e-12
Identities = 51/184 (27%), Positives = 75/184 (40%), Gaps = 3/184 (1%)
Query: 447 IDVDIPRCH-QYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNE 505
I +DI R C G H L +L A+ P Y QG+ S A + LN +
Sbjct: 451 IKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGM-SFIAAVLILNL-DT 508
Query: 506 ARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFA 565
A AF S + K F + + ++ Y A F + P+L H N P+++
Sbjct: 509 ADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYL 568
Query: 566 IPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLFS 625
I W T++S PL +WD F +G +GIL+ D L + F +
Sbjct: 569 IDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLT 628
Query: 626 DLPE 629
LPE
Sbjct: 629 RLPE 632
>AL833868-1|CAD38726.1| 381|Homo sapiens hypothetical protein
protein.
Length = 381
Score = 72.9 bits (171), Expect = 4e-12
Identities = 51/184 (27%), Positives = 75/184 (40%), Gaps = 3/184 (1%)
Query: 447 IDVDIPRCH-QYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNE 505
I +DI R C G H L +L A+ P Y QG+ S A + LN +
Sbjct: 154 IKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGM-SFIAAVLILNL-DT 211
Query: 506 ARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFA 565
A AF S + K F + + ++ Y A F + P+L H N P+++
Sbjct: 212 ADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYL 271
Query: 566 IPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLFS 625
I W T++S PL +WD F +G +GIL+ D L + F +
Sbjct: 272 IDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLT 331
Query: 626 DLPE 629
LPE
Sbjct: 332 RLPE 335
>AB037743-1|BAA92560.1| 702|Homo sapiens KIAA1322 protein protein.
Length = 702
Score = 72.9 bits (171), Expect = 4e-12
Identities = 51/184 (27%), Positives = 75/184 (40%), Gaps = 3/184 (1%)
Query: 447 IDVDIPRCH-QYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNE 505
I +DI R C G H L +L A+ P Y QG+ S A + LN +
Sbjct: 475 IKLDISRTFPNLCIFQQGGPYHDMLHSILGAYTCYRPDVGYVQGM-SFIAAVLILNL-DT 532
Query: 506 ARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFA 565
A AF S + K F + + ++ Y A F + P+L H N P+++
Sbjct: 533 ADAFIAFSNLLNKPCQMAFFRVDHGLMLTYFAAFEVFFEENLPKLFAHFKKNNLTPDIYL 592
Query: 566 IPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLFS 625
I W T++S PL +WD F +G +GIL+ D L + F +
Sbjct: 593 IDWIFTLYSKSLPLDLACRIWDVFCRDGEEFLFRTALGILKLFEDILTKMDFIHMAQFLT 652
Query: 626 DLPE 629
LPE
Sbjct: 653 RLPE 656
>BC114506-1|AAI14507.1| 370|Homo sapiens death-associated protein
kinase 2 protein.
Length = 370
Score = 72.5 bits (170), Expect = 5e-12
Identities = 70/252 (27%), Positives = 113/252 (44%), Gaps = 23/252 (9%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L + H N+ T D+ + + ++++ V G L D K+ LS EE + +Q+ +G+
Sbjct: 78 LRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGV 137
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH I H L +NI L+D N +KL ++G+ + G E G P +++PE
Sbjct: 138 NYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPE 197
Query: 160 TI-LNSGGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNS 218
+ G AD+W+ GVI L G P LG A A ++
Sbjct: 198 IVNYEPLGLEADMWSIGVITYILLSG-----ASP------FLGDTKQETLANITAVSYDF 246
Query: 219 IEE-YEQLPKYLQTLIEKCLQICPSKRATITEILQD--LSNVDTKE-MCAVKPPRGLMGC 274
EE + Q + + I K L KR TI E L+ ++ VD ++ M + L
Sbjct: 247 DEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENF 306
Query: 275 KLQYLYHWWQLA 286
+ QY+ W+L+
Sbjct: 307 RKQYVRRRWKLS 318
>AB018001-1|BAA88063.1| 370|Homo sapiens Death-associated protein
kinase 2 protein.
Length = 370
Score = 72.5 bits (170), Expect = 5e-12
Identities = 70/252 (27%), Positives = 113/252 (44%), Gaps = 23/252 (9%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L + H N+ T D+ + + ++++ V G L D K+ LS EE + +Q+ +G+
Sbjct: 78 LRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGV 137
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH I H L +NI L+D N +KL ++G+ + G E G P +++PE
Sbjct: 138 NYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPE 197
Query: 160 TI-LNSGGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNS 218
+ G AD+W+ GVI L G P LG A A ++
Sbjct: 198 IVNYEPLGLEADMWSIGVITYILLSG-----ASP------FLGDTKQETLANITAVSYDF 246
Query: 219 IEE-YEQLPKYLQTLIEKCLQICPSKRATITEILQD--LSNVDTKE-MCAVKPPRGLMGC 274
EE + Q + + I K L KR TI E L+ ++ VD ++ M + L
Sbjct: 247 DEEFFSQTSELAKDFIRKLLVKETRKRLTIQEALRHPWITPVDNQQAMVRRESVVNLENF 306
Query: 275 KLQYLYHWWQLA 286
+ QY+ W+L+
Sbjct: 307 RKQYVRRRWKLS 318
>AJ271722-1|CAB71146.1| 714|Homo sapiens putative serine/threonine
protein kinase MAK-V protein.
Length = 714
Score = 72.1 bits (169), Expect = 7e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 9/158 (5%)
Query: 42 GRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQ 98
G+ Q++ I HPN+ LDI+ ++ +V+ G +L KK+L E RQ
Sbjct: 112 GQIQQM--IRHPNITQLLDILETENSYYLVMELCPGGNLMHKIYEKKRLEESEARRYIRQ 169
Query: 99 VANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMT--YGGSE-VAFPLGQPRY 155
+ + +++LH + HR L +N+L+D + +KL ++G+ G S+ + G P Y
Sbjct: 170 LISAVEHLHRAGVVHRDLKIENLLLDEDNNIKLIDFGLSNCAGILGYSDPFSTQCGSPAY 229
Query: 156 LSPETILNSG-GPTADIWTFGVILLELCIGKLWAKLKP 192
+PE + GP D+W+ GV + + G L ++P
Sbjct: 230 AAPELLARKKYGPKIDVWSIGVNMYAMLTGTLPFTVEP 267
>Z48970-1|CAA88834.1| 303|Homo sapiens orf protein.
Length = 303
Score = 71.7 bits (168), Expect = 9e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDII---RGKHE-RIIVVAEVIGKSLAD 82
G GLP+ S++ + +RL + EHPN+ +D+ R E ++ +V E + + L
Sbjct: 45 GGGGLPI--STVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
Query: 83 LKKK-----LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L E I ++ RQ GL +LHAN I HR L +NIL+ G VKL ++G+
Sbjct: 103 YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLA 162
Query: 138 YMTYGGSEVAFPLGQPR-YLSPETILNSGGPT-ADIWTFGVILLEL 181
+ Y P+ Y +PE +L S T D+W+ G I E+
Sbjct: 163 RI-YSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEM 207
>X73458-1|CAA51837.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 71.7 bits (168), Expect = 9e-12
Identities = 57/191 (29%), Positives = 92/191 (48%), Gaps = 20/191 (10%)
Query: 69 IIVVAEVIGK-SLADLKKK---LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILID 124
+ VV E+ + SL +L K+ L+ E RQ+ G QYLH N + HR L N+ ++
Sbjct: 126 VFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLN 185
Query: 125 LNGKVKLFNYGIFY-MTYGGSEVAFPLGQPRYLSPETILNSGGP-TADIWTFGVILLELC 182
+ +VK+ ++G+ + Y G G P Y++PE + G D+W+ G I+ L
Sbjct: 186 EDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLL 245
Query: 183 IGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPS 242
+GK P L ++ RI + SI ++ + +LI+K LQ P+
Sbjct: 246 VGK-------PPFETSCLKETYL-----RIKKNEYSIPKH--INPVAASLIQKMLQTDPT 291
Query: 243 KRATITEILQD 253
R TI E+L D
Sbjct: 292 ARPTINELLND 302
>U81031-1|AAC39521.2| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 71.7 bits (168), Expect = 9e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDII---RGKHE-RIIVVAEVIGKSLAD 82
G GLP+ S++ + +RL + EHPN+ +D+ R E ++ +V E + + L
Sbjct: 45 GGGGLPI--STVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
Query: 83 LKKK-----LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L E I ++ RQ GL +LHAN I HR L +NIL+ G VKL ++G+
Sbjct: 103 YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLA 162
Query: 138 YMTYGGSEVAFPLGQPR-YLSPETILNSGGPT-ADIWTFGVILLEL 181
+ Y P+ Y +PE +L S T D+W+ G I E+
Sbjct: 163 RI-YSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEM 207
>U37022-1|AAC50506.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 71.7 bits (168), Expect = 9e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDII---RGKHE-RIIVVAEVIGKSLAD 82
G GLP+ S++ + +RL + EHPN+ +D+ R E ++ +V E + + L
Sbjct: 45 GGGGLPI--STVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
Query: 83 LKKK-----LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L E I ++ RQ GL +LHAN I HR L +NIL+ G VKL ++G+
Sbjct: 103 YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLA 162
Query: 138 YMTYGGSEVAFPLGQPR-YLSPETILNSGGPT-ADIWTFGVILLEL 181
+ Y P+ Y +PE +L S T D+W+ G I E+
Sbjct: 163 RI-YSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEM 207
>U01038-1|AAA56634.1| 603|Homo sapiens pLK protein.
Length = 603
Score = 71.7 bits (168), Expect = 9e-12
Identities = 57/191 (29%), Positives = 92/191 (48%), Gaps = 20/191 (10%)
Query: 69 IIVVAEVIGK-SLADLKKK---LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILID 124
+ VV E+ + SL +L K+ L+ E RQ+ G QYLH N + HR L N+ ++
Sbjct: 126 VFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLN 185
Query: 125 LNGKVKLFNYGIFY-MTYGGSEVAFPLGQPRYLSPETILNSGGP-TADIWTFGVILLELC 182
+ +VK+ ++G+ + Y G G P Y++PE + G D+W+ G I+ L
Sbjct: 186 EDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLL 245
Query: 183 IGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPS 242
+GK P L ++ RI + SI ++ + +LI+K LQ P+
Sbjct: 246 VGK-------PPFETSCLKETYL-----RIKKNEYSIPKH--INPVAASLIQKMLQTDPT 291
Query: 243 KRATITEILQD 253
R TI E+L D
Sbjct: 292 ARPTINELLND 302
>M14505-1|AAA35673.1| 303|Homo sapiens cyclin-dependent protein
kinase, type 4 protein.
Length = 303
Score = 71.7 bits (168), Expect = 9e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDII---RGKHE-RIIVVAEVIGKSLAD 82
G GLP+ S++ + +RL + EHPN+ +D+ R E ++ +V E + + L
Sbjct: 45 GGGGLPI--STVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
Query: 83 LKKK-----LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L E I ++ RQ GL +LHAN I HR L +NIL+ G VKL ++G+
Sbjct: 103 YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLA 162
Query: 138 YMTYGGSEVAFPLGQPR-YLSPETILNSGGPT-ADIWTFGVILLEL 181
+ Y P+ Y +PE +L S T D+W+ G I E+
Sbjct: 163 RI-YSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEM 207
>CR542247-1|CAG47043.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 71.7 bits (168), Expect = 9e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDII---RGKHE-RIIVVAEVIGKSLAD 82
G GLP+ S++ + +RL + EHPN+ +D+ R E ++ +V E + + L
Sbjct: 45 GGGGLPI--STVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
Query: 83 LKKK-----LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L E I ++ RQ GL +LHAN I HR L +NIL+ G VKL ++G+
Sbjct: 103 YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLA 162
Query: 138 YMTYGGSEVAFPLGQPR-YLSPETILNSGGPT-ADIWTFGVILLEL 181
+ Y P+ Y +PE +L S T D+W+ G I E+
Sbjct: 163 RI-YSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEM 207
>CR407668-1|CAG28596.1| 303|Homo sapiens CDK4 protein.
Length = 303
Score = 71.7 bits (168), Expect = 9e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDII---RGKHE-RIIVVAEVIGKSLAD 82
G GLP+ S++ + +RL + EHPN+ +D+ R E ++ +V E + + L
Sbjct: 45 GGGGLPI--STVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
Query: 83 LKKK-----LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L E I ++ RQ GL +LHAN I HR L +NIL+ G VKL ++G+
Sbjct: 103 YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLA 162
Query: 138 YMTYGGSEVAFPLGQPR-YLSPETILNSGGPT-ADIWTFGVILLEL 181
+ Y P+ Y +PE +L S T D+W+ G I E+
Sbjct: 163 RI-YSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEM 207
>BC014846-1|AAH14846.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 71.7 bits (168), Expect = 9e-12
Identities = 57/191 (29%), Positives = 92/191 (48%), Gaps = 20/191 (10%)
Query: 69 IIVVAEVIGK-SLADLKKK---LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILID 124
+ VV E+ + SL +L K+ L+ E RQ+ G QYLH N + HR L N+ ++
Sbjct: 126 VFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLN 185
Query: 125 LNGKVKLFNYGIFY-MTYGGSEVAFPLGQPRYLSPETILNSGGP-TADIWTFGVILLELC 182
+ +VK+ ++G+ + Y G G P Y++PE + G D+W+ G I+ L
Sbjct: 186 EDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLL 245
Query: 183 IGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPS 242
+GK P L ++ RI + SI ++ + +LI+K LQ P+
Sbjct: 246 VGK-------PPFETSCLKETYL-----RIKKNEYSIPKH--INPVAASLIQKMLQTDPT 291
Query: 243 KRATITEILQD 253
R TI E+L D
Sbjct: 292 ARPTINELLND 302
>BC010153-1|AAH10153.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 71.7 bits (168), Expect = 9e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDII---RGKHE-RIIVVAEVIGKSLAD 82
G GLP+ S++ + +RL + EHPN+ +D+ R E ++ +V E + + L
Sbjct: 45 GGGGLPI--STVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
Query: 83 LKKK-----LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L E I ++ RQ GL +LHAN I HR L +NIL+ G VKL ++G+
Sbjct: 103 YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLA 162
Query: 138 YMTYGGSEVAFPLGQPR-YLSPETILNSGGPT-ADIWTFGVILLEL 181
+ Y P+ Y +PE +L S T D+W+ G I E+
Sbjct: 163 RI-YSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEM 207
>BC005864-1|AAH05864.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 71.7 bits (168), Expect = 9e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDII---RGKHE-RIIVVAEVIGKSLAD 82
G GLP+ S++ + +RL + EHPN+ +D+ R E ++ +V E + + L
Sbjct: 45 GGGGLPI--STVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
Query: 83 LKKK-----LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L E I ++ RQ GL +LHAN I HR L +NIL+ G VKL ++G+
Sbjct: 103 YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLA 162
Query: 138 YMTYGGSEVAFPLGQPR-YLSPETILNSGGPT-ADIWTFGVILLEL 181
+ Y P+ Y +PE +L S T D+W+ G I E+
Sbjct: 163 RI-YSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEM 207
>BC003644-1|AAH03644.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 71.7 bits (168), Expect = 9e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDII---RGKHE-RIIVVAEVIGKSLAD 82
G GLP+ S++ + +RL + EHPN+ +D+ R E ++ +V E + + L
Sbjct: 45 GGGGLPI--STVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
Query: 83 LKKK-----LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L E I ++ RQ GL +LHAN I HR L +NIL+ G VKL ++G+
Sbjct: 103 YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLA 162
Query: 138 YMTYGGSEVAFPLGQPR-YLSPETILNSGGPT-ADIWTFGVILLEL 181
+ Y P+ Y +PE +L S T D+W+ G I E+
Sbjct: 163 RI-YSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEM 207
>BC003002-1|AAH03002.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 71.7 bits (168), Expect = 9e-12
Identities = 57/191 (29%), Positives = 92/191 (48%), Gaps = 20/191 (10%)
Query: 69 IIVVAEVIGK-SLADLKKK---LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILID 124
+ VV E+ + SL +L K+ L+ E RQ+ G QYLH N + HR L N+ ++
Sbjct: 126 VFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLN 185
Query: 125 LNGKVKLFNYGIFY-MTYGGSEVAFPLGQPRYLSPETILNSGGP-TADIWTFGVILLELC 182
+ +VK+ ++G+ + Y G G P Y++PE + G D+W+ G I+ L
Sbjct: 186 EDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLL 245
Query: 183 IGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPS 242
+GK P L ++ RI + SI ++ + +LI+K LQ P+
Sbjct: 246 VGK-------PPFETSCLKETYL-----RIKKNEYSIPKH--INPVAASLIQKMLQTDPT 291
Query: 243 KRATITEILQD 253
R TI E+L D
Sbjct: 292 ARPTINELLND 302
>BC002369-1|AAH02369.1| 603|Homo sapiens polo-like kinase 1
(Drosophila) protein.
Length = 603
Score = 71.7 bits (168), Expect = 9e-12
Identities = 57/191 (29%), Positives = 92/191 (48%), Gaps = 20/191 (10%)
Query: 69 IIVVAEVIGK-SLADLKKK---LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILID 124
+ VV E+ + SL +L K+ L+ E RQ+ G QYLH N + HR L N+ ++
Sbjct: 126 VFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLN 185
Query: 125 LNGKVKLFNYGIFY-MTYGGSEVAFPLGQPRYLSPETILNSGGP-TADIWTFGVILLELC 182
+ +VK+ ++G+ + Y G G P Y++PE + G D+W+ G I+ L
Sbjct: 186 EDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLL 245
Query: 183 IGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPS 242
+GK P L ++ RI + SI ++ + +LI+K LQ P+
Sbjct: 246 VGK-------PPFETSCLKETYL-----RIKKNEYSIPKH--INPVAASLIQKMLQTDPT 291
Query: 243 KRATITEILQD 253
R TI E+L D
Sbjct: 292 ARPTINELLND 302
>AF507942-1|AAM23014.1| 303|Homo sapiens cyclin-dependent kinase 4
protein.
Length = 303
Score = 71.7 bits (168), Expect = 9e-12
Identities = 54/166 (32%), Positives = 83/166 (50%), Gaps = 14/166 (8%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDII---RGKHE-RIIVVAEVIGKSLAD 82
G GLP+ S++ + +RL + EHPN+ +D+ R E ++ +V E + + L
Sbjct: 45 GGGGLPI--STVREVALLRRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRT 102
Query: 83 LKKK-----LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L E I ++ RQ GL +LHAN I HR L +NIL+ G VKL ++G+
Sbjct: 103 YLDKAPPPGLPAETIKDLMRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLA 162
Query: 138 YMTYGGSEVAFPLGQPR-YLSPETILNSGGPT-ADIWTFGVILLEL 181
+ Y P+ Y +PE +L S T D+W+ G I E+
Sbjct: 163 RI-YSYQMALTPVVVTLWYRAPEVLLQSTYATPVDMWSVGCIFAEM 207
>Z99127-7|CAI18937.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 71.3 bits (167), Expect = 1e-11
Identities = 56/224 (25%), Positives = 103/224 (45%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERI---DKETPTPTDRQIDVDIPRCHQYCWLLCG 463
+P +R +VW L G + + ++Y + D + R I P H Y + G
Sbjct: 539 VPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFP-AHDY-FKDTG 596
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + Y QG L A + L E +AF L + + +
Sbjct: 597 GDGQESLYKICKAYSVYDEDIGYCQGQSFLAA--VLLLHMPEEQAFCVLVKIMYDYGLRD 654
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
++N ++ KF+Q+ + P L +H D+N ++A WFLT+F+ FPL
Sbjct: 655 LYRNN---FEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLC 711
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG ++ + + +L+ ++ LL++ F + F
Sbjct: 712 MVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFF 755
>BT007185-1|AAP35849.1| 898|Homo sapiens STE20-like kinase protein.
Length = 898
Score = 71.3 bits (167), Expect = 1e-11
Identities = 61/221 (27%), Positives = 102/221 (46%), Gaps = 24/221 (10%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
IL + L ++HPN Y +H +V+ +G S +DL KK L EI +
Sbjct: 69 ILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 127
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
+GL YLH++ + HR + NIL+ G+VKL ++G M + +G P +
Sbjct: 128 THGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF---VGTPYW 184
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G DIW+ G+ +EL A+ KP P+ ++
Sbjct: 185 MAPEVILAMDEGQYDGKVDIWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 232
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQ 252
IA+ + + + + ++ CLQ P +R T E+L+
Sbjct: 233 IAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLR 273
>BC048980-1|AAH48980.1| 574|Homo sapiens protein kinase,
AMP-activated, alpha 1 catalytic subunit protein.
Length = 574
Score = 71.3 bits (167), Expect = 1e-11
Identities = 35/104 (33%), Positives = 55/104 (52%), Gaps = 2/104 (1%)
Query: 85 KKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGS 144
K+L +E + +Q+ +G+ Y H + + HR L +N+L+D + K+ ++G+ M G
Sbjct: 135 KELDEKESRRLFQQILSGVDYCHRHMVVHRDLKPENVLLDAHMNAKIADFGLSNMMSDGE 194
Query: 145 EVAFPLGQPRYLSPETILNS--GGPTADIWTFGVILLELCIGKL 186
+ G P Y +PE I GP DIW+ GVIL L G L
Sbjct: 195 FLRTSCGSPNYAAPEVISGRLYAGPEVDIWSSGVILYALLCGTL 238
>BC002756-1|AAH02756.1| 898|Homo sapiens TAO kinase 3 protein.
Length = 898
Score = 71.3 bits (167), Expect = 1e-11
Identities = 61/221 (27%), Positives = 102/221 (46%), Gaps = 24/221 (10%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
IL + L ++HPN Y +H +V+ +G S +DL KK L EI +
Sbjct: 69 ILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 127
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
+GL YLH++ + HR + NIL+ G+VKL ++G M + +G P +
Sbjct: 128 THGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF---VGTPYW 184
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G DIW+ G+ +EL A+ KP P+ ++
Sbjct: 185 MAPEVILAMDEGQYDGKVDIWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 232
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQ 252
IA+ + + + + ++ CLQ P +R T E+L+
Sbjct: 233 IAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLR 273
>AY364260-1|AAQ76819.1| 468|Homo sapiens HHL protein.
Length = 468
Score = 71.3 bits (167), Expect = 1e-11
Identities = 56/224 (25%), Positives = 103/224 (45%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERI---DKETPTPTDRQIDVDIPRCHQYCWLLCG 463
+P +R +VW L G + + ++Y + D + R I P H Y + G
Sbjct: 192 VPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFP-AHDY-FKDTG 249
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + Y QG L A + L E +AF L + + +
Sbjct: 250 GDGQESLYKICKAYSVYDEDIGYCQGQSFLAA--VLLLHMPEEQAFCVLVKIMYDYGLRD 307
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
++N ++ KF+Q+ + P L +H D+N ++A WFLT+F+ FPL
Sbjct: 308 LYRNN---FEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLC 364
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG ++ + + +L+ ++ LL++ F + F
Sbjct: 365 MVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFF 408
>AL591108-1|CAH70225.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 71.3 bits (167), Expect = 1e-11
Identities = 56/224 (25%), Positives = 103/224 (45%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERI---DKETPTPTDRQIDVDIPRCHQYCWLLCG 463
+P +R +VW L G + + ++Y + D + R I P H Y + G
Sbjct: 539 VPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFP-AHDY-FKDTG 596
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + Y QG L A + L E +AF L + + +
Sbjct: 597 GDGQESLYKICKAYSVYDEDIGYCQGQSFLAA--VLLLHMPEEQAFCVLVKIMYDYGLRD 654
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
++N ++ KF+Q+ + P L +H D+N ++A WFLT+F+ FPL
Sbjct: 655 LYRNN---FEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLC 711
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG ++ + + +L+ ++ LL++ F + F
Sbjct: 712 MVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFF 755
>AL161671-6|CAI16281.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 71.3 bits (167), Expect = 1e-11
Identities = 56/224 (25%), Positives = 103/224 (45%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERI---DKETPTPTDRQIDVDIPRCHQYCWLLCG 463
+P +R +VW L G + + ++Y + D + R I P H Y + G
Sbjct: 539 VPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFP-AHDY-FKDTG 596
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + Y QG L A + L E +AF L + + +
Sbjct: 597 GDGQESLYKICKAYSVYDEDIGYCQGQSFLAA--VLLLHMPEEQAFCVLVKIMYDYGLRD 654
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
++N ++ KF+Q+ + P L +H D+N ++A WFLT+F+ FPL
Sbjct: 655 LYRNN---FEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLC 711
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG ++ + + +L+ ++ LL++ F + F
Sbjct: 712 MVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFF 755
>AL136377-4|CAI22935.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 71.3 bits (167), Expect = 1e-11
Identities = 56/224 (25%), Positives = 103/224 (45%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERI---DKETPTPTDRQIDVDIPRCHQYCWLLCG 463
+P +R +VW L G + + ++Y + D + R I P H Y + G
Sbjct: 539 VPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFP-AHDY-FKDTG 596
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + Y QG L A + L E +AF L + + +
Sbjct: 597 GDGQESLYKICKAYSVYDEDIGYCQGQSFLAA--VLLLHMPEEQAFCVLVKIMYDYGLRD 654
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
++N ++ KF+Q+ + P L +H D+N ++A WFLT+F+ FPL
Sbjct: 655 LYRNN---FEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLC 711
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG ++ + + +L+ ++ LL++ F + F
Sbjct: 712 MVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFF 755
>AL031286-3|CAI22382.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 71.3 bits (167), Expect = 1e-11
Identities = 56/224 (25%), Positives = 103/224 (45%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERI---DKETPTPTDRQIDVDIPRCHQYCWLLCG 463
+P +R +VW L G + + ++Y + D + R I P H Y + G
Sbjct: 539 VPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFP-AHDY-FKDTG 596
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + Y QG L A + L E +AF L + + +
Sbjct: 597 GDGQESLYKICKAYSVYDEDIGYCQGQSFLAA--VLLLHMPEEQAFCVLVKIMYDYGLRD 654
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
++N ++ KF+Q+ + P L +H D+N ++A WFLT+F+ FPL
Sbjct: 655 LYRNN---FEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLC 711
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG ++ + + +L+ ++ LL++ F + F
Sbjct: 712 MVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFF 755
>AL022400-4|CAI22878.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 71.3 bits (167), Expect = 1e-11
Identities = 56/224 (25%), Positives = 103/224 (45%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERI---DKETPTPTDRQIDVDIPRCHQYCWLLCG 463
+P +R +VW L G + + ++Y + D + R I P H Y + G
Sbjct: 539 VPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFP-AHDY-FKDTG 596
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + Y QG L A + L E +AF L + + +
Sbjct: 597 GDGQESLYKICKAYSVYDEDIGYCQGQSFLAA--VLLLHMPEEQAFCVLVKIMYDYGLRD 654
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
++N ++ KF+Q+ + P L +H D+N ++A WFLT+F+ FPL
Sbjct: 655 LYRNN---FEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLC 711
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG ++ + + +L+ ++ LL++ F + F
Sbjct: 712 MVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFF 755
>AL022171-4|CAI20384.1| 815|Homo sapiens RAB GTPase activating
protein 1-like protein.
Length = 815
Score = 71.3 bits (167), Expect = 1e-11
Identities = 56/224 (25%), Positives = 103/224 (45%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERI---DKETPTPTDRQIDVDIPRCHQYCWLLCG 463
+P +R +VW L G + + ++Y + D + R I P H Y + G
Sbjct: 539 VPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFP-AHDY-FKDTG 596
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + Y QG L A + L E +AF L + + +
Sbjct: 597 GDGQESLYKICKAYSVYDEDIGYCQGQSFLAA--VLLLHMPEEQAFCVLVKIMYDYGLRD 654
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
++N ++ KF+Q+ + P L +H D+N ++A WFLT+F+ FPL
Sbjct: 655 LYRNN---FEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLC 711
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG ++ + + +L+ ++ LL++ F + F
Sbjct: 712 MVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFF 755
>AK095838-1|BAC04635.1| 815|Homo sapiens protein ( Homo sapiens
cDNA FLJ38519 fis, clone HCHON2000751, moderately
similar to Rab6 GTPase activating protein. ).
Length = 815
Score = 71.3 bits (167), Expect = 1e-11
Identities = 56/224 (25%), Positives = 103/224 (45%), Gaps = 15/224 (6%)
Query: 409 IPPLVRGDVWAALLGVVGD--IEEQYERI---DKETPTPTDRQIDVDIPRCHQYCWLLCG 463
+P +R +VW L G + + ++Y + D + R I P H Y + G
Sbjct: 539 VPEALRAEVWQLLAGCHDNQAMLDRYRILITKDSAQESVITRDIHRTFP-AHDY-FKDTG 596
Query: 464 SAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKF 523
G +L ++ KA+ + + Y QG L A + L E +AF L + + +
Sbjct: 597 GDGQESLYKICKAYSVYDEDIGYCQGQSFLAA--VLLLHMPEEQAFCVLVKIMYDYGLRD 654
Query: 524 FLKDNSAVIKEYLAKFWQMAAFHE---PRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
++N ++ KF+Q+ + P L +H D+N ++A WFLT+F+ FPL
Sbjct: 655 LYRNN---FEDLHCKFYQLERLMQEQLPDLHSHFSDLNLEAHMYASQWFLTLFTAKFPLC 711
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECILLF 624
+ H+ D L EG ++ + + +L+ ++ LL++ F + F
Sbjct: 712 MVFHIIDLLLCEGLNIIFHVALALLKTSKEDLLQADFEGALKFF 755
>AF181985-1|AAF25817.1| 898|Homo sapiens serine/threonine kinase
protein.
Length = 898
Score = 71.3 bits (167), Expect = 1e-11
Identities = 61/221 (27%), Positives = 102/221 (46%), Gaps = 24/221 (10%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
IL + L ++HPN Y +H +V+ +G S +DL KK L EI +
Sbjct: 69 ILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 127
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
+GL YLH++ + HR + NIL+ G+VKL ++G M + +G P +
Sbjct: 128 THGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF---VGTPYW 184
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G DIW+ G+ +EL A+ KP P+ ++
Sbjct: 185 MAPEVILAMDEGQYDGKVDIWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 232
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQ 252
IA+ + + + + ++ CLQ P +R T E+L+
Sbjct: 233 IAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLR 273
>AF179867-1|AAF14559.1| 898|Homo sapiens STE20-like kinase protein.
Length = 898
Score = 71.3 bits (167), Expect = 1e-11
Identities = 61/221 (27%), Positives = 102/221 (46%), Gaps = 24/221 (10%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
IL + L ++HPN Y +H +V+ +G S +DL KK L EI +
Sbjct: 69 ILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 127
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
+GL YLH++ + HR + NIL+ G+VKL ++G M + +G P +
Sbjct: 128 THGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF---VGTPYW 184
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G DIW+ G+ +EL A+ KP P+ ++
Sbjct: 185 MAPEVILAMDEGQYDGKVDIWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 232
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQ 252
IA+ + + + + ++ CLQ P +R T E+L+
Sbjct: 233 IAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLR 273
>AF135158-1|AAG09131.1| 898|Homo sapiens serine kinase protein.
Length = 898
Score = 71.3 bits (167), Expect = 1e-11
Identities = 61/221 (27%), Positives = 102/221 (46%), Gaps = 24/221 (10%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
IL + L ++HPN Y +H +V+ +G S +DL KK L EI +
Sbjct: 69 ILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 127
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
+GL YLH++ + HR + NIL+ G+VKL ++G M + +G P +
Sbjct: 128 THGALHGLAYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMASPANSF---VGTPYW 184
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G DIW+ G+ +EL A+ KP P+ ++
Sbjct: 185 MAPEVILAMDEGQYDGKVDIWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 232
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQ 252
IA+ + + + + ++ CLQ P +R T E+L+
Sbjct: 233 IAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLR 273
>L19559-1|AAA36659.1| 603|Homo sapiens protein kinase protein.
Length = 603
Score = 70.9 bits (166), Expect = 2e-11
Identities = 57/191 (29%), Positives = 92/191 (48%), Gaps = 20/191 (10%)
Query: 69 IIVVAEVIGK-SLADLKKK---LSTEEIINVARQVANGLQYLHANNITHRTLSDDNILID 124
+ VV E+ + SL +L K+ L+ E RQ+ G QYLH N + HR L N+ ++
Sbjct: 126 VFVVLELCRRRSLLELHKRRKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLN 185
Query: 125 LNGKVKLFNYGIFY-MTYGGSEVAFPLGQPRYLSPETILNSGGP-TADIWTFGVILLELC 182
+ +VK+ ++G+ + Y G G P Y++PE + G D+W+ G I+ L
Sbjct: 186 EDLEVKIGDFGLATKVEYDGERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLL 245
Query: 183 IGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPS 242
+GK P L ++ RI + SI ++ + +LI+K LQ P+
Sbjct: 246 VGK-------PPFETSCLKETYL-----RIKKNEYSIPKH--INPVAASLIQKMLQTDPT 291
Query: 243 KRATITEILQD 253
R TI E+L D
Sbjct: 292 ARPTINELLGD 302
>BC051798-1|AAH51798.1| 1426|Homo sapiens TAOK2 protein protein.
Length = 1426
Score = 70.9 bits (166), Expect = 2e-11
Identities = 61/220 (27%), Positives = 101/220 (45%), Gaps = 25/220 (11%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
I+ + L + HPN Y +H +V+ +G S +DL KK L EI V
Sbjct: 257 IIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAV 315
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
GL YLH++N+ HR + NIL+ G VKL ++G + + +G P +
Sbjct: 316 THGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSF---VGTPYW 372
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G D+W+ G+ +EL A+ KP P+ ++
Sbjct: 373 MAPEVILAMDEGQYDGKVDVWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 420
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEIL 251
IA+ + + + +Y + ++ CLQ P R T +E+L
Sbjct: 421 IAQNESPVLQSGHWSEYFRNFVDSCLQKIPQDRPT-SEVL 459
>BC031825-1|AAH31825.1| 560|Homo sapiens TAOK2 protein protein.
Length = 560
Score = 70.9 bits (166), Expect = 2e-11
Identities = 61/220 (27%), Positives = 101/220 (45%), Gaps = 25/220 (11%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
I+ + L + HPN Y +H +V+ +G S +DL KK L EI V
Sbjct: 73 IIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAV 131
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
GL YLH++N+ HR + NIL+ G VKL ++G + + +G P +
Sbjct: 132 THGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSF---VGTPYW 188
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G D+W+ G+ +EL A+ KP P+ ++
Sbjct: 189 MAPEVILAMDEGQYDGKVDVWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 236
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEIL 251
IA+ + + + +Y + ++ CLQ P R T +E+L
Sbjct: 237 IAQNESPVLQSGHWSEYFRNFVDSCLQKIPQDRPT-SEVL 275
>BC015204-1|AAH15204.1| 762|Homo sapiens Unknown (protein for
IMAGE:3878048) protein.
Length = 762
Score = 70.9 bits (166), Expect = 2e-11
Identities = 61/220 (27%), Positives = 101/220 (45%), Gaps = 25/220 (11%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
I+ + L + HPN Y +H +V+ +G S +DL KK L EI V
Sbjct: 73 IIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAV 131
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
GL YLH++N+ HR + NIL+ G VKL ++G + + +G P +
Sbjct: 132 THGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSF---VGTPYW 188
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G D+W+ G+ +EL A+ KP P+ ++
Sbjct: 189 MAPEVILAMDEGQYDGKVDVWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 236
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEIL 251
IA+ + + + +Y + ++ CLQ P R T +E+L
Sbjct: 237 IAQNESPVLQSGHWSEYFRNFVDSCLQKIPQDRPT-SEVL 275
>AF263313-1|AAG38503.1| 1049|Homo sapiens STE20-like kinase protein.
Length = 1049
Score = 70.9 bits (166), Expect = 2e-11
Identities = 61/220 (27%), Positives = 101/220 (45%), Gaps = 25/220 (11%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
I+ + L + HPN Y +H +V+ +G S +DL KK L EI V
Sbjct: 73 IIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAV 131
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
GL YLH++N+ HR + NIL+ G VKL ++G + + +G P +
Sbjct: 132 THGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSF---VGTPYW 188
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G D+W+ G+ +EL A+ KP P+ ++
Sbjct: 189 MAPEVILAMDEGQYDGKVDVWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 236
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEIL 251
IA+ + + + +Y + ++ CLQ P R T +E+L
Sbjct: 237 IAQNESPVLQSGHWSEYFRNFVDSCLQKIPQDRPT-SEVL 275
>AF263311-1|AAG38501.1| 898|Homo sapiens STE20-like kinase protein.
Length = 898
Score = 70.9 bits (166), Expect = 2e-11
Identities = 61/221 (27%), Positives = 102/221 (46%), Gaps = 24/221 (10%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
IL + L ++HPN Y +H +V+ +G S +DL KK L EI +
Sbjct: 69 ILKEVKFLRQLKHPNTIEYKGCYLKEHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAI 127
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
+GL YLH++ + HR + NIL+ G+VKL ++G M + +G P +
Sbjct: 128 THGALHGLTYLHSHALIHRDIKAGNILLTEPGQVKLADFGSASMAPPANSF---VGTPYW 184
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G DIW+ G+ +EL A+ KP P+ ++
Sbjct: 185 MAPEVILAMDEGQYDGKVDIWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 232
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQ 252
IA+ + + + + ++ CLQ P +R T E+L+
Sbjct: 233 IAQNDSPTLQSNEWTDSFRRFVDYCLQKIPQERPTSAELLR 273
>AF061943-1|AAD45616.1| 1235|Homo sapiens prostate derived
STE20-like kinase PSK protein.
Length = 1235
Score = 70.9 bits (166), Expect = 2e-11
Identities = 61/220 (27%), Positives = 101/220 (45%), Gaps = 25/220 (11%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
I+ + L + HPN Y +H +V+ +G S +DL KK L EI V
Sbjct: 73 IIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAV 131
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
GL YLH++N+ HR + NIL+ G VKL ++G + + +G P +
Sbjct: 132 THGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSF---VGTPYW 188
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G D+W+ G+ +EL A+ KP P+ ++
Sbjct: 189 MAPEVILAMDEGQYDGKVDVWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 236
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEIL 251
IA+ + + + +Y + ++ CLQ P R T +E+L
Sbjct: 237 IAQNESPVLQSGHWSEYFRNFVDSCLQKIPQDRPT-SEVL 275
>AF052941-1|AAC35001.1| 370|Homo sapiens DAP-kinase related protein
1 protein.
Length = 370
Score = 70.9 bits (166), Expect = 2e-11
Identities = 45/146 (30%), Positives = 73/146 (50%), Gaps = 8/146 (5%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVANGL 103
L + H N+ T D+ + + ++++ V G L D K+ LS EE + +Q+ +G+
Sbjct: 78 LRQVLHHNVITLHDVYENRTDVVLILELVSGGELFDFLAQKESLSEEEATSFIKQILDGV 137
Query: 104 QYLHANNITHRTLSDDNI-LIDLN---GKVKLFNYGIFYMTYGGSEVAFPLGQPRYLSPE 159
YLH I H L +NI L+D N +KL ++G+ + G E G P +++PE
Sbjct: 138 NYLHTKKIAHFDLKPENIMLLDKNIPIPHIKLIDFGLAHEIEDGVEFKNIFGTPEFVAPE 197
Query: 160 TI-LNSGGPTADIWTFGVILLELCIG 184
+ G AD+W+ GVI L G
Sbjct: 198 IVNYEPLGLEADMWSIGVITYILLSG 223
>AB209179-1|BAD92416.1| 546|Homo sapiens polo-like kinase variant
protein.
Length = 546
Score = 70.9 bits (166), Expect = 2e-11
Identities = 51/172 (29%), Positives = 82/172 (47%), Gaps = 16/172 (9%)
Query: 84 KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFY-MTYG 142
+K L+ E RQ+ G QYLH N + HR L N+ ++ + +VK+ ++G+ + Y
Sbjct: 88 RKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYD 147
Query: 143 GSEVAFPLGQPRYLSPETILNSGGP-TADIWTFGVILLELCIGKLWAKLKPGPILRRILG 201
G G P Y++PE + G D+W+ G I+ L +GK P L
Sbjct: 148 GERKKTLCGTPNYIAPEVLSKKGHSFEVDVWSIGCIMYTLLVGK-------PPFETSCLK 200
Query: 202 LVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
++ RI + SI ++ + +LI+K LQ P+ R TI E+L D
Sbjct: 201 ETYL-----RIKKNEYSIPKH--INPVAASLIQKMLQTDPTARPTINELLND 245
>AB020688-1|BAA74904.2| 1064|Homo sapiens KIAA0881 protein protein.
Length = 1064
Score = 70.9 bits (166), Expect = 2e-11
Identities = 61/220 (27%), Positives = 101/220 (45%), Gaps = 25/220 (11%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL----KKKLSTEEIINV 95
I+ + L + HPN Y +H +V+ +G S +DL KK L EI V
Sbjct: 88 IIKEVRFLQKLRHPNTIQYRGCYLREHTAWLVMEYCLG-SASDLLEVHKKPLQEVEIAAV 146
Query: 96 ARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRY 155
GL YLH++N+ HR + NIL+ G VKL ++G + + +G P +
Sbjct: 147 THGALQGLAYLHSHNMIHRDVKAGNILLSEPGLVKLGDFGSASIMAPANSF---VGTPYW 203
Query: 156 LSPETIL--NSG--GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKR 211
++PE IL + G D+W+ G+ +EL A+ KP P+ ++
Sbjct: 204 MAPEVILAMDEGQYDGKVDVWSLGITCIEL------AERKP-PLFN-----MNAMSALYH 251
Query: 212 IAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEIL 251
IA+ + + + +Y + ++ CLQ P R T +E+L
Sbjct: 252 IAQNESPVLQSGHWSEYFRNFVDSCLQKIPQDRPT-SEVL 290
>U18297-1|AAA83254.1| 487|Homo sapiens MST1 protein.
Length = 487
Score = 70.1 bits (164), Expect = 3e-11
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 213
Query: 178 LLELCIGKL-WAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 214 AIEMAEGKRPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 261
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 262 LVKSPEQRATATQLLQ 277
>BC035596-1|AAH35596.1| 681|Homo sapiens PAK6 protein protein.
Length = 681
Score = 70.1 bits (164), Expect = 3e-11
Identities = 53/191 (27%), Positives = 98/191 (51%), Gaps = 18/191 (9%)
Query: 67 ERIIVVAEVI-GKSLADL--KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILI 123
E + V+ E + G +L D+ + +L+ E+I V V L YLHA + HR + D+IL+
Sbjct: 475 EELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILL 534
Query: 124 DLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSGGPT-ADIWTFGVILLEL 181
L+G+VKL ++G ++ + +G P +++PE I S T DIW+ G++++E+
Sbjct: 535 TLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEM 594
Query: 182 CIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQIC 240
G+ + P ++R+ + P ++ H ++ L+ +E+ L
Sbjct: 595 VDGEPPYFSDSPVQAMKRLR-----DSPPPKLKNSH-------KVSPVLRDFLERMLVRD 642
Query: 241 PSKRATITEIL 251
P +RAT E+L
Sbjct: 643 PQERATAQELL 653
>AJ236915-1|CAC18720.1| 681|Homo sapiens pak5 protein protein.
Length = 681
Score = 70.1 bits (164), Expect = 3e-11
Identities = 53/191 (27%), Positives = 98/191 (51%), Gaps = 18/191 (9%)
Query: 67 ERIIVVAEVI-GKSLADL--KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILI 123
E + V+ E + G +L D+ + +L+ E+I V V L YLHA + HR + D+IL+
Sbjct: 475 EELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILL 534
Query: 124 DLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSGGPT-ADIWTFGVILLEL 181
L+G+VKL ++G ++ + +G P +++PE I S T DIW+ G++++E+
Sbjct: 535 TLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEM 594
Query: 182 CIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQIC 240
G+ + P ++R+ + P ++ H ++ L+ +E+ L
Sbjct: 595 VDGEPPYFSDSPVQAMKRLR-----DSPPPKLKNSH-------KVSPVLRDFLERMLVRD 642
Query: 241 PSKRATITEIL 251
P +RAT E+L
Sbjct: 643 PQERATAQELL 653
>AF276893-1|AAF82800.1| 681|Homo sapiens p21-activated protein
kinase 6 protein.
Length = 681
Score = 70.1 bits (164), Expect = 3e-11
Identities = 53/191 (27%), Positives = 98/191 (51%), Gaps = 18/191 (9%)
Query: 67 ERIIVVAEVI-GKSLADL--KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILI 123
E + V+ E + G +L D+ + +L+ E+I V V L YLHA + HR + D+IL+
Sbjct: 475 EELWVLMEFLQGGALTDIVSQVRLNEEQIATVCEAVLQALAYLHAQGVIHRDIKSDSILL 534
Query: 124 DLNGKVKLFNYGI-FYMTYGGSEVAFPLGQPRYLSPETILNSGGPT-ADIWTFGVILLEL 181
L+G+VKL ++G ++ + +G P +++PE I S T DIW+ G++++E+
Sbjct: 535 TLDGRVKLSDFGFCAQISKDVPKRKSLVGTPYWMAPEVISRSLYATEVDIWSLGIMVIEM 594
Query: 182 CIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQIC 240
G+ + P ++R+ + P ++ H ++ L+ +E+ L
Sbjct: 595 VDGEPPYFSDSPVQAMKRLR-----DSPPPKLKNSH-------KVSPVLRDFLERMLVRD 642
Query: 241 PSKRATITEIL 251
P +RAT E+L
Sbjct: 643 PQERATAQELL 653
>Z93016-2|CAI19815.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 69.7 bits (163), Expect = 4e-11
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 213
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 214 AIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 261
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 262 LVKSPEQRATATQLLQ 277
>Z93016-1|CAB07508.2| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 69.7 bits (163), Expect = 4e-11
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 213
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 214 AIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 261
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 262 LVKSPEQRATATQLLQ 277
>X03484-1|CAA27204.1| 648|Homo sapiens protein ( Human mRNA for raf
oncogene. ).
Length = 648
Score = 69.7 bits (163), Expect = 4e-11
Identities = 46/185 (24%), Positives = 92/185 (49%), Gaps = 17/185 (9%)
Query: 78 KSLADLKKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L + K ++I++ARQ A G+ YLHA NI HR + +NI + VK+ ++G+
Sbjct: 431 KHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLA 490
Query: 138 YMT---YGGSEVAFPLGQPRYLSPETI-LNSGGP---TADIWTFGVILLELCIGKL-WAK 189
+ G +V P G +++PE I + P +D++++G++L EL G+L ++
Sbjct: 491 TVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSH 550
Query: 190 LKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITE 249
+ + ++G + + ++ Y+ PK ++ L+ C++ +R +
Sbjct: 551 INNRDQIIFMVGRGYASPDLSKL---------YKNCPKAMKRLVADCVKKVKEERPLFPQ 601
Query: 250 ILQDL 254
IL +
Sbjct: 602 ILSSI 606
>U60207-1|AAB17262.1| 487|Homo sapiens serine/threonine protein
kinase Krs-2 protein.
Length = 487
Score = 69.7 bits (163), Expect = 4e-11
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 213
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 214 AIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 261
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 262 LVKSPEQRATATQLLQ 277
>L00212-1|AAA60247.1| 421|Homo sapiens RAF1 protein.
Length = 421
Score = 69.7 bits (163), Expect = 4e-11
Identities = 46/185 (24%), Positives = 92/185 (49%), Gaps = 17/185 (9%)
Query: 78 KSLADLKKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L + K ++I++ARQ A G+ YLHA NI HR + +NI + VK+ ++G+
Sbjct: 204 KHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLA 263
Query: 138 YMT---YGGSEVAFPLGQPRYLSPETI-LNSGGP---TADIWTFGVILLELCIGKL-WAK 189
+ G +V P G +++PE I + P +D++++G++L EL G+L ++
Sbjct: 264 TVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELITGELPYSH 323
Query: 190 LKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITE 249
+ + ++G + + ++ Y+ PK ++ L+ C++ +R +
Sbjct: 324 INNRDQIIFMVGRGYASPDLSKL---------YKNCPKAMKRLVADCVKKVKEERPLFPQ 374
Query: 250 ILQDL 254
IL +
Sbjct: 375 ILSSI 379
>BC093768-1|AAH93768.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 69.7 bits (163), Expect = 4e-11
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 213
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 214 AIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 261
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 262 LVKSPEQRATATQLLQ 277
>BC058916-1|AAH58916.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 69.7 bits (163), Expect = 4e-11
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 213
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 214 AIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 261
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 262 LVKSPEQRATATQLLQ 277
>BC041799-1|AAH41799.1| 592|Homo sapiens CDKL3 protein protein.
Length = 592
Score = 69.7 bits (163), Expect = 4e-11
Identities = 58/229 (25%), Positives = 103/229 (44%), Gaps = 25/229 (10%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKK----LSTEEIINVARQVANG 102
L H NL +++ R K ++I +V E I ++ D + L ++ + Q+
Sbjct: 54 LKQFHHENLVNLIEVFRQK-KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRA 112
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPR-YLSPETI 161
+ YLH+NNI HR + +NIL+ +G KL ++G ++ R Y +PE +
Sbjct: 113 IDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELV 172
Query: 162 L--NSGGPTADIWTFGVILLELCIGKLWAK------------LKPG---PILRRILGL-- 202
L S G DIW G +++E+ G + LK G P L+ I
Sbjct: 173 LKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSP 232
Query: 203 VHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEIL 251
+ ++ N+ ++Y +L L ++ CLQI P+ R + +++L
Sbjct: 233 IFAGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLL 281
>BC018119-1|AAH18119.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 69.7 bits (163), Expect = 4e-11
Identities = 46/185 (24%), Positives = 92/185 (49%), Gaps = 17/185 (9%)
Query: 78 KSLADLKKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L + K ++I++ARQ A G+ YLHA NI HR + +NI + VK+ ++G+
Sbjct: 431 KHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLA 490
Query: 138 YMT---YGGSEVAFPLGQPRYLSPETI-LNSGGP---TADIWTFGVILLELCIGKL-WAK 189
+ G +V P G +++PE I + P +D++++G++L EL G+L ++
Sbjct: 491 TVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSH 550
Query: 190 LKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITE 249
+ + ++G + + ++ Y+ PK ++ L+ C++ +R +
Sbjct: 551 INNRDQIIFMVGRGYASPDLSKL---------YKNCPKAMKRLVADCVKKVKEERPLFPQ 601
Query: 250 ILQDL 254
IL +
Sbjct: 602 ILSSI 606
>BC015332-1|AAH15332.1| 405|Homo sapiens Unknown (protein for
IMAGE:4400771) protein.
Length = 405
Score = 69.7 bits (163), Expect = 4e-11
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 213
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 214 AIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 261
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 262 LVKSPEQRATATQLLQ 277
>AY271661-1|AAP03432.1| 648|Homo sapiens v-raf-1 murine leukemia
viral oncogene homolog 1 protein.
Length = 648
Score = 69.7 bits (163), Expect = 4e-11
Identities = 46/185 (24%), Positives = 92/185 (49%), Gaps = 17/185 (9%)
Query: 78 KSLADLKKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K L + K ++I++ARQ A G+ YLHA NI HR + +NI + VK+ ++G+
Sbjct: 431 KHLHVQETKFQMFQLIDIARQTAQGMDYLHAKNIIHRDMKSNNIFLHEGLTVKIGDFGLA 490
Query: 138 YMT---YGGSEVAFPLGQPRYLSPETI-LNSGGP---TADIWTFGVILLELCIGKL-WAK 189
+ G +V P G +++PE I + P +D++++G++L EL G+L ++
Sbjct: 491 TVKSRWSGSQQVEQPTGSVLWMAPEVIRMQDNNPFSFQSDVYSYGIVLYELMTGELPYSH 550
Query: 190 LKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITE 249
+ + ++G + + ++ Y+ PK ++ L+ C++ +R +
Sbjct: 551 INNRDQIIFMVGRGYASPDLSKL---------YKNCPKAMKRLVADCVKKVKEERPLFPQ 601
Query: 250 ILQDL 254
IL +
Sbjct: 602 ILSSI 606
>AL109839-4|CAI95634.1| 487|Homo sapiens serine/threonine kinase 4
protein.
Length = 487
Score = 69.7 bits (163), Expect = 4e-11
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 213
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 214 AIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 261
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 262 LVKSPEQRATATQLLQ 277
>AL109839-3|CAI95633.1| 462|Homo sapiens serine/threonine kinase 4
protein.
Length = 462
Score = 69.7 bits (163), Expect = 4e-11
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 213
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 214 AIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 261
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 262 LVKSPEQRATATQLLQ 277
>AF130372-1|AAF36509.1| 455|Homo sapiens serine-threonine protein
kinase NKIAMRE protein.
Length = 455
Score = 69.7 bits (163), Expect = 4e-11
Identities = 58/229 (25%), Positives = 103/229 (44%), Gaps = 25/229 (10%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKK----LSTEEIINVARQVANG 102
L H NL +++ R K ++I +V E I ++ D + L ++ + Q+
Sbjct: 54 LKQFHHENLVNLIEVFRQK-KKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRA 112
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPR-YLSPETI 161
+ YLH+NNI HR + +NIL+ +G KL ++G ++ R Y +PE +
Sbjct: 113 IDYLHSNNIIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELV 172
Query: 162 L--NSGGPTADIWTFGVILLELCIGKLWAK------------LKPG---PILRRILGL-- 202
L S G DIW G +++E+ G + LK G P L+ I
Sbjct: 173 LKDTSYGKPVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSP 232
Query: 203 VHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEIL 251
+ ++ N+ ++Y +L L ++ CLQI P+ R + +++L
Sbjct: 233 IFAGVVLPQVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLL 281
>AB209315-1|BAD92552.1| 511|Homo sapiens serine/threonine kinase 4
variant protein.
Length = 511
Score = 69.7 bits (163), Expect = 4e-11
Identities = 54/196 (27%), Positives = 95/196 (48%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 118 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 177
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 178 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 237
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 238 AIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 285
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 286 LVKSPEQRATATQLLQ 301
>AC016738-3|AAY14824.1| 897|Homo sapiens unknown protein.
Length = 897
Score = 69.3 bits (162), Expect = 5e-11
Identities = 77/309 (24%), Positives = 128/309 (41%), Gaps = 29/309 (9%)
Query: 324 TGVLYDRRIAKYSIELLQSRLSHVSAHDYYPLMHERKK----QNDAVTLPKTIRERDTEY 379
T + D R +E++ S+ S S + PLMH Q P + R+
Sbjct: 175 TSMCSDHRFG--DLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSRE--- 229
Query: 380 QFYRLLWFQRLLHGYPYTAPYIRAE-----AEIDIPPLVRGDVWAALLGVVGDIEEQ--- 431
Q LW + Y T R E + IP +RG +W V D+
Sbjct: 230 QIKISLWNDHFVE-YGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGY 288
Query: 432 YERIDKETPTP---TDRQIDVDIPRCHQYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQ 488
Y + +E+ +I+ D+ R G L+R+L A+ NP+ Y Q
Sbjct: 289 YGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQ 348
Query: 489 GLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAK--FWQMAAFH 546
++ LT+ + L + E AF L A + L +F N VI + + F ++ H
Sbjct: 349 SMNILTS--VLLLYTKEEEAFWLLVAVCERMLPDYF---NHRVIGAQVDQSVFEELIKGH 403
Query: 547 EPRLATHLHDINFVPELFAIPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILR 606
P LA H++D++ + + ++ WFLT+F + PL V++ D F +G +G+ +L
Sbjct: 404 LPELAEHMNDLSALASV-SLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLE 462
Query: 607 QLRDTLLES 615
+ L S
Sbjct: 463 ANAEDLCSS 471
>AB024057-1|BAA75489.1| 897|Homo sapiens vascular
Rab-GAP/TBC-containing protein protein.
Length = 897
Score = 69.3 bits (162), Expect = 5e-11
Identities = 77/309 (24%), Positives = 128/309 (41%), Gaps = 29/309 (9%)
Query: 324 TGVLYDRRIAKYSIELLQSRLSHVSAHDYYPLMHERKK----QNDAVTLPKTIRERDTEY 379
T + D R +E++ S+ S S + PLMH Q P + R+
Sbjct: 175 TSMCSDHRFG--DLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSRE--- 229
Query: 380 QFYRLLWFQRLLHGYPYTAPYIRAE-----AEIDIPPLVRGDVWAALLGVVGDIEEQ--- 431
Q LW + Y T R E + IP +RG +W V D+
Sbjct: 230 QIKISLWNDHFVE-YGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGY 288
Query: 432 YERIDKETPTP---TDRQIDVDIPRCHQYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQ 488
Y + +E+ +I+ D+ R G L+R+L A+ NP+ Y Q
Sbjct: 289 YGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQ 348
Query: 489 GLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAK--FWQMAAFH 546
++ LT+ + L + E AF L A + L +F N VI + + F ++ H
Sbjct: 349 SMNILTS--VLLLYTKEEEAFWLLVAVCERMLPDYF---NHRVIGAQVDQSVFEELIKGH 403
Query: 547 EPRLATHLHDINFVPELFAIPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILR 606
P LA H++D++ + + ++ WFLT+F + PL V++ D F +G +G+ +L
Sbjct: 404 LPELAEHMNDLSALASV-SLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLE 462
Query: 607 QLRDTLLES 615
+ L S
Sbjct: 463 ANAEDLCSS 471
>AB017114-1|BAA76517.1| 733|Homo sapiens AD 3 protein.
Length = 733
Score = 69.3 bits (162), Expect = 5e-11
Identities = 77/309 (24%), Positives = 128/309 (41%), Gaps = 29/309 (9%)
Query: 324 TGVLYDRRIAKYSIELLQSRLSHVSAHDYYPLMHERKK----QNDAVTLPKTIRERDTEY 379
T + D R +E++ S+ S S + PLMH Q P + R+
Sbjct: 171 TSMCSDHRFG--DLEMMSSQNSEESEKEKSPLMHPDALVTAFQQSGSQSPDSRMSRE--- 225
Query: 380 QFYRLLWFQRLLHGYPYTAPYIRAE-----AEIDIPPLVRGDVWAALLGVVGDIEEQ--- 431
Q LW + Y T R E + IP +RG +W V D+
Sbjct: 226 QIKISLWNDHFVE-YGRTVCMFRTEKIRKLVAMGIPESLRGRLWLLFSDAVTDLASHPGY 284
Query: 432 YERIDKETPTP---TDRQIDVDIPRCHQYCWLLCGSAGHRTLKRLLKAWLLTNPQYVYWQ 488
Y + +E+ +I+ D+ R G L+R+L A+ NP+ Y Q
Sbjct: 285 YGNLVEESLGKCCLVTEEIERDLHRSLPEHPAFQNETGIAALRRVLTAYAHRNPKIGYCQ 344
Query: 489 GLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKFFLKDNSAVIKEYLAK--FWQMAAFH 546
++ LT+ + L + E AF L A + L +F N VI + + F ++ H
Sbjct: 345 SMNILTS--VLLLYTKEEEAFWLLVAVCERMLPDYF---NHRVIGAQVDQSVFEELIKGH 399
Query: 547 EPRLATHLHDINFVPELFAIPWFLTMFSHVFPLHKIVHLWDAFLVEGPSLPLFMGVGILR 606
P LA H++D++ + + ++ WFLT+F + PL V++ D F +G +G+ +L
Sbjct: 400 LPELAEHMNDLSALASV-SLSWFLTLFLSIMPLESAVNVVDCFFYDGIKAIFQLGLAVLE 458
Query: 607 QLRDTLLES 615
+ L S
Sbjct: 459 ANAEDLCSS 467
>U60206-1|AAB17261.1| 491|Homo sapiens serine/threonine protein
kinase Krs-1 protein.
Length = 491
Score = 68.9 bits (161), Expect = 6e-11
Identities = 55/196 (28%), Positives = 94/196 (47%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L +EI + + GL+YLH HR +
Sbjct: 91 KNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAG 150
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 151 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 210
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E ++KC
Sbjct: 211 SIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDDFTDFVKKC 258
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 259 LVKNPEQRATATQLLQ 274
>U26424-1|AAC50386.1| 491|Homo sapiens MST2 protein.
Length = 491
Score = 68.9 bits (161), Expect = 6e-11
Identities = 55/196 (28%), Positives = 94/196 (47%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L +EI + + GL+YLH HR +
Sbjct: 91 KNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAG 150
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 151 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 210
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E ++KC
Sbjct: 211 SIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDDFTDFVKKC 258
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 259 LVKNPEQRATATQLLQ 274
>CT841514-1|CAJ86444.1| 508|Homo sapiens dJ130H16.2 protein.
Length = 508
Score = 68.9 bits (161), Expect = 6e-11
Identities = 55/212 (25%), Positives = 92/212 (43%), Gaps = 9/212 (4%)
Query: 401 IRAEAEIDIPPLVRGDVWAALLGVVGDIEEQYERIDKETPTPTD-RQIDV---DIPRCHQ 456
IR + IPP +RG W L G +++ + D+ +P D + +DV D+ R
Sbjct: 104 IRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFP 163
Query: 457 YCWLLCGSAGH--RTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSA 514
+ + GH + L R+LKA+ L P+ Y Q + A + L +AF CL
Sbjct: 164 FHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAA--VLLMHMPAEQAFWCLVQ 221
Query: 515 FVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFS 574
K+L ++ + A+ + F + P HL P L+ WF+ FS
Sbjct: 222 ICEKYLPGYYSEKLEAIQLDGEILFSLLQKV-SPVAHKHLSRQKIDPLLYMTEWFMCAFS 280
Query: 575 HVFPLHKIVHLWDAFLVEGPSLPLFMGVGILR 606
P ++ +WD F EG + +G+ +L+
Sbjct: 281 RTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
>CR456441-1|CAG30327.1| 749|Homo sapiens dJ1042K10.2 protein.
Length = 749
Score = 68.9 bits (161), Expect = 6e-11
Identities = 60/229 (26%), Positives = 98/229 (42%), Gaps = 11/229 (4%)
Query: 409 IPPLVRGDVWAALLGVVG---DIEEQYERIDKETP---TPTDRQIDVDIPRC--HQYCWL 460
IP +R +W L G + + E Y I K + T +QI+ D+ R C+
Sbjct: 115 IPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFA 174
Query: 461 LCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFL 520
GS G L+R+L+A P+ Y QG + A L F E AF +SA + L
Sbjct: 175 SMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAA--CLLLFLEEEDAFWMMSAIIEDLL 232
Query: 521 HKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
+ ++ + + PRL L + + L + WFLT F+ V +
Sbjct: 233 PASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIK 292
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECIL-LFSDLP 628
++ +WD F EG + + +G+L + L++S + I SD+P
Sbjct: 293 LLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIP 341
>BC010640-1|AAH10640.1| 491|Homo sapiens serine/threonine kinase 3
(STE20 homolog, yeast) protein.
Length = 491
Score = 68.9 bits (161), Expect = 6e-11
Identities = 55/196 (28%), Positives = 94/196 (47%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L +EI + + GL+YLH HR +
Sbjct: 91 KNTDLWIVMEYCGAGSVSDIIRLRNKTLIEDEIATILKSTLKGLEYLHFMRKIHRDIKAG 150
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P +++PE I G ADIW+ G+
Sbjct: 151 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFWMAPEVIQEIGYNCVADIWSLGIT 210
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E ++KC
Sbjct: 211 SIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDDFTDFVKKC 258
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 259 LVKNPEQRATATQLLQ 274
>BC008078-1|AAH08078.1| 749|Homo sapiens RUN and TBC1 domain
containing 3 protein.
Length = 749
Score = 68.9 bits (161), Expect = 6e-11
Identities = 60/229 (26%), Positives = 98/229 (42%), Gaps = 11/229 (4%)
Query: 409 IPPLVRGDVWAALLGVVG---DIEEQYERIDKETP---TPTDRQIDVDIPRC--HQYCWL 460
IP +R +W L G + + E Y I K + T +QI+ D+ R C+
Sbjct: 115 IPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFA 174
Query: 461 LCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFL 520
GS G L+R+L+A P+ Y QG + A L F E AF +SA + L
Sbjct: 175 SMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAA--CLLLFLEEEDAFWMMSAIIEDLL 232
Query: 521 HKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
+ ++ + + PRL L + + L + WFLT F+ V +
Sbjct: 233 PASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIK 292
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECIL-LFSDLP 628
++ +WD F EG + + +G+L + L++S + I SD+P
Sbjct: 293 LLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIP 341
>AY308849-1|AAQ81879.1| 749|Homo sapiens merlin binding protein
protein.
Length = 749
Score = 68.9 bits (161), Expect = 6e-11
Identities = 60/229 (26%), Positives = 98/229 (42%), Gaps = 11/229 (4%)
Query: 409 IPPLVRGDVWAALLGVVG---DIEEQYERIDKETP---TPTDRQIDVDIPRC--HQYCWL 460
IP +R +W L G + + E Y I K + T +QI+ D+ R C+
Sbjct: 115 IPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFA 174
Query: 461 LCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFL 520
GS G L+R+L+A P+ Y QG + A L F E AF +SA + L
Sbjct: 175 SMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAA--CLLLFLEEEDAFWMMSAIIEDLL 232
Query: 521 HKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
+ ++ + + PRL L + + L + WFLT F+ V +
Sbjct: 233 PASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIK 292
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECIL-LFSDLP 628
++ +WD F EG + + +G+L + L++S + I SD+P
Sbjct: 293 LLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIP 341
>AL022238-3|CAA18266.1| 777|Homo sapiens protein ( Human DNA
sequence from clone RP5-1042K10 on chromosome
22q13.1-13.2. ).
Length = 777
Score = 68.9 bits (161), Expect = 6e-11
Identities = 60/229 (26%), Positives = 98/229 (42%), Gaps = 11/229 (4%)
Query: 409 IPPLVRGDVWAALLGVVG---DIEEQYERIDKETP---TPTDRQIDVDIPRC--HQYCWL 460
IP +R +W L G + + E Y I K + T +QI+ D+ R C+
Sbjct: 115 IPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFA 174
Query: 461 LCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFL 520
GS G L+R+L+A P+ Y QG + A L F E AF +SA + L
Sbjct: 175 SMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAA--CLLLFLEEEDAFWMMSAIIEDLL 232
Query: 521 HKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
+ ++ + + PRL L + + L + WFLT F+ V +
Sbjct: 233 PASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIK 292
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECIL-LFSDLP 628
++ +WD F EG + + +G+L + L++S + I SD+P
Sbjct: 293 LLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIP 341
>AK091248-1|BAC03620.1| 340|Homo sapiens protein ( Homo sapiens
cDNA FLJ33929 fis, clone CTONG2017458, moderately
similar to Homo sapiens mRNA for vascular
Rab-GAP/TBC-containing ).
Length = 340
Score = 68.9 bits (161), Expect = 6e-11
Identities = 45/148 (30%), Positives = 74/148 (50%), Gaps = 4/148 (2%)
Query: 466 GHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFLHKFFL 525
G L+R+L A+ NP+ Y Q ++ LT+ + L + E AF L A + L +F
Sbjct: 45 GISALRRVLTAYAYRNPKIGYCQAMNILTS--VLLLYAKEEEAFWLLVAVCERMLPDYFN 102
Query: 526 KDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLHKIVHL 585
+ + + A F ++ H P+L H+ D+ F + ++ WFLT+F V P+ V++
Sbjct: 103 RRIIGALVDQ-AVFEELIKDHLPQLTEHMTDMTFFSSV-SLSWFLTLFISVLPIESAVNV 160
Query: 586 WDAFLVEGPSLPLFMGVGILRQLRDTLL 613
D F +G L +G+ IL D LL
Sbjct: 161 VDCFFYDGIKAILQLGLAILDYNLDKLL 188
>AK074656-1|BAC11117.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ90175 fis, clone MAMMA1000496, weakly similar to
MIC1 PROTEIN. ).
Length = 508
Score = 68.9 bits (161), Expect = 6e-11
Identities = 55/212 (25%), Positives = 92/212 (43%), Gaps = 9/212 (4%)
Query: 401 IRAEAEIDIPPLVRGDVWAALLGVVGDIEEQYERIDKETPTPTD-RQIDV---DIPRCHQ 456
IR + IPP +RG W L G +++ + D+ +P D + +DV D+ R
Sbjct: 104 IRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFP 163
Query: 457 YCWLLCGSAGH--RTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSA 514
+ + GH + L R+LKA+ L P+ Y Q + A + L +AF CL
Sbjct: 164 FHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAA--VLLMHMPAEQAFWCLVQ 221
Query: 515 FVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFS 574
K+L ++ + A+ + F + P HL P L+ WF+ FS
Sbjct: 222 ICEKYLPGYYSEKLEAIQLDGEILFSLLQKV-SPVAHKHLSRQKIDPLLYMTEWFMCAFS 280
Query: 575 HVFPLHKIVHLWDAFLVEGPSLPLFMGVGILR 606
P ++ +WD F EG + +G+ +L+
Sbjct: 281 RTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
>AK000006-1|BAA92231.1| 401|Homo sapiens FLJ00006 protein protein.
Length = 401
Score = 68.9 bits (161), Expect = 6e-11
Identities = 60/229 (26%), Positives = 98/229 (42%), Gaps = 11/229 (4%)
Query: 409 IPPLVRGDVWAALLGVVG---DIEEQYERIDKETP---TPTDRQIDVDIPRC--HQYCWL 460
IP +R +W L G + + E Y I K + T +QI+ D+ R C+
Sbjct: 59 IPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFA 118
Query: 461 LCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFL 520
GS G L+R+L+A P+ Y QG + A L F E AF +SA + L
Sbjct: 119 SMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAA--CLLLFLEEEDAFWMMSAIIEDLL 176
Query: 521 HKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
+ ++ + + PRL L + + L + WFLT F+ V +
Sbjct: 177 PASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIK 236
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECIL-LFSDLP 628
++ +WD F EG + + +G+L + L++S + I SD+P
Sbjct: 237 LLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIP 285
>AF331038-1|AAK35048.1| 508|Homo sapiens EPI64 protein.
Length = 508
Score = 68.9 bits (161), Expect = 6e-11
Identities = 55/212 (25%), Positives = 92/212 (43%), Gaps = 9/212 (4%)
Query: 401 IRAEAEIDIPPLVRGDVWAALLGVVGDIEEQYERIDKETPTPTD-RQIDV---DIPRCHQ 456
IR + IPP +RG W L G +++ + D+ +P D + +DV D+ R
Sbjct: 104 IRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFP 163
Query: 457 YCWLLCGSAGH--RTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSA 514
+ + GH + L R+LKA+ L P+ Y Q + A + L +AF CL
Sbjct: 164 FHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAA--VLLMHMPAEQAFWCLVQ 221
Query: 515 FVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFS 574
K+L ++ + A+ + F + P HL P L+ WF+ FS
Sbjct: 222 ICEKYLPGYYSEKLEAIQLDGEILFSLLQKV-SPVAHKHLSRQKIDPLLYMTEWFMCAFS 280
Query: 575 HVFPLHKIVHLWDAFLVEGPSLPLFMGVGILR 606
P ++ +WD F EG + +G+ +L+
Sbjct: 281 RTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 312
>AC004997-3|AAC23434.1| 438|Homo sapiens WUGSC:H_DJ130H16.2
protein.
Length = 438
Score = 68.9 bits (161), Expect = 6e-11
Identities = 55/212 (25%), Positives = 92/212 (43%), Gaps = 9/212 (4%)
Query: 401 IRAEAEIDIPPLVRGDVWAALLGVVGDIEEQYERIDKETPTPTD-RQIDV---DIPRCHQ 456
IR + IPP +RG W L G +++ + D+ +P D + +DV D+ R
Sbjct: 34 IRLRCQKGIPPSLRGRAWQYLSGGKVKLQQNPGKFDELDMSPGDPKWLDVIERDLHRQFP 93
Query: 457 YCWLLCGSAGH--RTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSA 514
+ + GH + L R+LKA+ L P+ Y Q + A + L +AF CL
Sbjct: 94 FHEMFVSRGGHGQQDLFRVLKAYTLYRPEEGYCQAQAPIAA--VLLMHMPAEQAFWCLVQ 151
Query: 515 FVPKFLHKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFS 574
K+L ++ + A+ + F + P HL P L+ WF+ FS
Sbjct: 152 ICEKYLPGYYSEKLEAIQLDGEILFSLLQKV-SPVAHKHLSRQKIDPLLYMTEWFMCAFS 210
Query: 575 HVFPLHKIVHLWDAFLVEGPSLPLFMGVGILR 606
P ++ +WD F EG + +G+ +L+
Sbjct: 211 RTLPWSSVLRVWDMFFCEGVKIIFRVGLVLLK 242
>AB196956-1|BAE02561.1| 749|Homo sapiens
Rab-GTPase-activating-protein-like protein protein.
Length = 749
Score = 68.9 bits (161), Expect = 6e-11
Identities = 60/229 (26%), Positives = 98/229 (42%), Gaps = 11/229 (4%)
Query: 409 IPPLVRGDVWAALLGVVG---DIEEQYERIDKETP---TPTDRQIDVDIPRC--HQYCWL 460
IP +R +W L G + + E Y I K + T +QI+ D+ R C+
Sbjct: 115 IPHGMRPQLWMRLSGALQKKRNSELSYREIVKNSSNDETIAAKQIEKDLLRTMPSNACFA 174
Query: 461 LCGSAGHRTLKRLLKAWLLTNPQYVYWQGLDSLTAPFMYLNFCNEARAFACLSAFVPKFL 520
GS G L+R+L+A P+ Y QG + A L F E AF +SA + L
Sbjct: 175 SMGSIGVPRLRRVLRALAWLYPEIGYCQGTGMVAA--CLLLFLEEEDAFWMMSAIIEDLL 232
Query: 521 HKFFLKDNSAVIKEYLAKFWQMAAFHEPRLATHLHDINFVPELFAIPWFLTMFSHVFPLH 580
+ ++ + + PRL L + + L + WFLT F+ V +
Sbjct: 233 PASYFSTTLLGVQTDQRVLRHLIVQYLPRLDKLLQEHDIELSLITLHWFLTAFASVVDIK 292
Query: 581 KIVHLWDAFLVEGPSLPLFMGVGILRQLRDTLLESGFNECIL-LFSDLP 628
++ +WD F EG + + +G+L + L++S + I SD+P
Sbjct: 293 LLLRIWDLFFYEGSRVLFQLTLGMLHLKEEELIQSENSASIFNTLSDIP 341
>BC029511-1|AAH29511.1| 405|Homo sapiens STK4 protein protein.
Length = 405
Score = 68.5 bits (160), Expect = 8e-11
Identities = 54/196 (27%), Positives = 94/196 (47%), Gaps = 20/196 (10%)
Query: 65 KHERIIVVAEVIGK-SLADL----KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDD 119
K+ + +V E G S++D+ K L+ +EI + + GL+YLH HR +
Sbjct: 94 KNTDLWIVMEYCGAGSVSDIIRLRNKTLTEDEIATILQSTLKGLEYLHFMRKIHRDIKAG 153
Query: 120 NILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVI 177
NIL++ G KL ++G+ +T ++ +G P ++PE I G ADIW+ G+
Sbjct: 154 NILLNTEGHAKLADFGVAGQLTDTMAKRNTVIGTPFLMAPEVIQEIGYNCVADIWSLGIT 213
Query: 178 LLELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKC 236
+E+ GK +A + P R + ++ N P + + E +++C
Sbjct: 214 AIEMAEGKPPYADIHP----MRAIFMIPTNPPP--------TFRKPELWSDNFTDFVKQC 261
Query: 237 LQICPSKRATITEILQ 252
L P +RAT T++LQ
Sbjct: 262 LVKSPEQRATATQLLQ 277
>AK075004-1|BAC11348.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ90523 fis, clone NT2RP4000634, highly similar to
Homo sapiens mitogen-activated protein kinase kinase
kinase ).
Length = 423
Score = 68.1 bits (159), Expect = 1e-10
Identities = 52/172 (30%), Positives = 82/172 (47%), Gaps = 12/172 (6%)
Query: 32 PLTPSSISILG-RAQRLLSIEHPNLCTYLDIIRGKHERII-VVAEVI-GKSLADLKKKLS 88
P T ++ L Q L ++ H + Y +R E+ + + E + G S+ D K
Sbjct: 198 PETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYG 257
Query: 89 --TEEIIN-VARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYG----IFYMTY 141
TE + RQ+ G+ YLH+N I HR + NIL D G VKL ++G + +
Sbjct: 258 ALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICL 317
Query: 142 GGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILLELCIGK-LWAKLK 191
G+ + G P ++SPE I G G ADIW+ ++E+ K WA+ +
Sbjct: 318 SGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFE 369
>AF239798-1|AAF63496.1| 619|Homo sapiens protein kinase MEKK2b
protein.
Length = 619
Score = 68.1 bits (159), Expect = 1e-10
Identities = 52/172 (30%), Positives = 82/172 (47%), Gaps = 12/172 (6%)
Query: 32 PLTPSSISILG-RAQRLLSIEHPNLCTYLDIIRGKHERII-VVAEVI-GKSLADLKKKLS 88
P T ++ L Q L ++ H + Y +R E+ + + E + G S+ D K
Sbjct: 394 PETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYG 453
Query: 89 --TEEIIN-VARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYG----IFYMTY 141
TE + RQ+ G+ YLH+N I HR + NIL D G VKL ++G + +
Sbjct: 454 ALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICL 513
Query: 142 GGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILLELCIGK-LWAKLK 191
G+ + G P ++SPE I G G ADIW+ ++E+ K WA+ +
Sbjct: 514 SGTGMKSVTGTPYWMSPEVISGQGYGRKADIWSVACTVVEMLTEKPPWAEFE 565
>AC110926-2|AAY15070.1| 270|Homo sapiens unknown protein.
Length = 270
Score = 68.1 bits (159), Expect = 1e-10
Identities = 52/172 (30%), Positives = 82/172 (47%), Gaps = 12/172 (6%)
Query: 32 PLTPSSISILG-RAQRLLSIEHPNLCTYLDIIRGKHERII-VVAEVI-GKSLADLKKKLS 88
P T ++ L Q L ++ H + Y +R E+ + + E + G S+ D K
Sbjct: 45 PETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYG 104
Query: 89 --TEEIIN-VARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYG----IFYMTY 141
TE + RQ+ G+ YLH+N I HR + NIL D G VKL ++G + +
Sbjct: 105 ALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICL 164
Query: 142 GGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILLELCIGK-LWAKLK 191
G+ + G P ++SPE I G G ADIW+ ++E+ K WA+ +
Sbjct: 165 SGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFE 216
>AB209055-1|BAD92292.1| 272|Homo sapiens phosphorylase kinase,
gamma 2 (testis) variant protein.
Length = 272
Score = 68.1 bits (159), Expect = 1e-10
Identities = 67/233 (28%), Positives = 99/233 (42%), Gaps = 25/233 (10%)
Query: 97 RQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYL 156
R + + +LHANNI HR L +NIL+D N +++L ++G G ++ G P YL
Sbjct: 1 RSLLEAVSFLHANNIVHRDLKPENILLDDNMQIRLSDFGFSCHLEPGEKLRELCGTPGYL 60
Query: 157 SPETILNS-------GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPA 209
+PE + S G D+W GVIL L G P R+IL L + +
Sbjct: 61 APEILKCSMDETHPGYGKEVDLWACGVILFTLLAGS-----PPFWHRRQILMLRMIME-- 113
Query: 210 KRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQDLSNVDTKEMCAVKPPR 269
+ S E++ ++ LI + LQ+ P R T + LQ E C P
Sbjct: 114 ---GQYQFSSPEWDDRSSTVKDLISRLLQVDPEARLTAEQALQH----PFFERCEGSQPW 166
Query: 270 GLMGCKLQYLYHWWQLAGGDIQVELKR-NGLIKNS---PPILSIPVAILLDGC 318
L + + W LA G + + R L KN+ P V L+D C
Sbjct: 167 NLTPRQRFRVAVWTVLAAGRVALSTHRVRPLTKNALLRDPYALRSVRHLIDNC 219
>AB208963-1|BAD92200.1| 621|Homo sapiens Protein kinase MEKK2b
variant protein.
Length = 621
Score = 68.1 bits (159), Expect = 1e-10
Identities = 52/172 (30%), Positives = 82/172 (47%), Gaps = 12/172 (6%)
Query: 32 PLTPSSISILG-RAQRLLSIEHPNLCTYLDIIRGKHERII-VVAEVI-GKSLADLKKKLS 88
P T ++ L Q L ++ H + Y +R E+ + + E + G S+ D K
Sbjct: 396 PETSKEVNALECEIQLLKNLLHERIVQYYGCLRDPQEKTLSIFMEYMPGGSIKDQLKAYG 455
Query: 89 --TEEIIN-VARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYG----IFYMTY 141
TE + RQ+ G+ YLH+N I HR + NIL D G VKL ++G + +
Sbjct: 456 ALTENVTRKYTRQILEGVHYLHSNMIVHRDIKGANILRDSTGNVKLGDFGASKRLQTICL 515
Query: 142 GGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILLELCIGK-LWAKLK 191
G+ + G P ++SPE I G G ADIW+ ++E+ K WA+ +
Sbjct: 516 SGTGMKSVTGTPYWMSPEVISGEGYGRKADIWSVACTVVEMLTEKPPWAEFE 567
>X75932-1|CAA53536.1| 603|Homo sapiens Serine/Threonine protein
kinase protein.
Length = 603
Score = 67.7 bits (158), Expect = 1e-10
Identities = 50/172 (29%), Positives = 81/172 (47%), Gaps = 16/172 (9%)
Query: 84 KKKLSTEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFY-MTYG 142
+K L+ E RQ+ G QYLH N + HR L N+ ++ + +VK+ ++G+ + Y
Sbjct: 145 RKALTEPEARYYLRQIVLGCQYLHRNRVIHRDLKLGNLFLNEDLEVKIGDFGLATKVEYD 204
Query: 143 GSEVAFPLGQPRYLSPETILNSGGP-TADIWTFGVILLELCIGKLWAKLKPGPILRRILG 201
G G P Y++PE + D+W+ G I+ L +GK P L
Sbjct: 205 GERKKTLCGTPNYIAPEVLSKKEHSFEVDVWSIGCIMYTLLVGK-------PPFETSCLK 257
Query: 202 LVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
++ RI + SI ++ + +LI+K LQ P+ R TI E+L D
Sbjct: 258 ETYL-----RIKKNEYSIPKH--INPVAASLIQKMLQTDPTARPTINELLND 302
>D86959-1|BAA13195.2| 1164|Homo sapiens KIAA0204 protein protein.
Length = 1164
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 95 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 154
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 155 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 214
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 215 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 259
>D79997-1|BAA11492.2| 656|Homo sapiens KIAA0175 protein.
Length = 656
Score = 67.3 bits (157), Expect = 2e-10
Identities = 41/149 (27%), Positives = 71/149 (47%), Gaps = 7/149 (4%)
Query: 45 QRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVAN 101
+ L ++ H ++C ++ ++ +V+ G L D + +LS EE V RQ+ +
Sbjct: 64 EALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVS 123
Query: 102 GLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP--LGQPRYLSPE 159
+ Y+H+ HR L +N+L D K+KL ++G+ G + G Y +PE
Sbjct: 124 AVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPE 183
Query: 160 TILNSG--GPTADIWTFGVILLELCIGKL 186
I G AD+W+ G++L L G L
Sbjct: 184 LIQGKSYLGSEADVWSMGILLYVLMCGFL 212
>BT019619-1|AAV38425.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 91 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 150
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 151 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 210
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 211 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 256
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 257 KEPSFRPTAKELLK 270
>BC111565-1|AAI11566.1| 1204|Homo sapiens SLK protein protein.
Length = 1204
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 83 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 142
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 143 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 202
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 247
>BC065378-1|AAH65378.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 91 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 150
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 151 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 210
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 211 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 256
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 257 KEPSFRPTAKELLK 270
>BC064804-1|AAH64804.1| 617|Homo sapiens SLK protein protein.
Length = 617
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 83 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 142
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 143 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 202
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 247
>BC047885-1|AAH47885.1| 426|Homo sapiens SLK protein protein.
Length = 426
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 83 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 142
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 143 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 202
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 247
>BC047762-1|AAH47762.1| 614|Homo sapiens SLK protein protein.
Length = 614
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 83 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 142
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 143 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 202
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 247
>BC035578-1|AAH35578.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 91 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 150
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 151 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 210
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 211 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 256
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 257 KEPSFRPTAKELLK 270
>BC014039-1|AAH14039.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 67.3 bits (157), Expect = 2e-10
Identities = 41/149 (27%), Positives = 71/149 (47%), Gaps = 7/149 (4%)
Query: 45 QRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVAN 101
+ L ++ H ++C ++ ++ +V+ G L D + +LS EE V RQ+ +
Sbjct: 59 EALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVS 118
Query: 102 GLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP--LGQPRYLSPE 159
+ Y+H+ HR L +N+L D K+KL ++G+ G + G Y +PE
Sbjct: 119 AVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPE 178
Query: 160 TILNSG--GPTADIWTFGVILLELCIGKL 186
I G AD+W+ G++L L G L
Sbjct: 179 LIQGKSYLGSEADVWSMGILLYVLMCGFL 207
>AL442063-1|CAI16995.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 67.3 bits (157), Expect = 2e-10
Identities = 41/149 (27%), Positives = 71/149 (47%), Gaps = 7/149 (4%)
Query: 45 QRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVAN 101
+ L ++ H ++C ++ ++ +V+ G L D + +LS EE V RQ+ +
Sbjct: 59 EALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVS 118
Query: 102 GLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP--LGQPRYLSPE 159
+ Y+H+ HR L +N+L D K+KL ++G+ G + G Y +PE
Sbjct: 119 AVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPE 178
Query: 160 TILNSG--GPTADIWTFGVILLELCIGKL 186
I G AD+W+ G++L L G L
Sbjct: 179 LIQGKSYLGSEADVWSMGILLYVLMCGFL 207
>AL360170-2|CAH70404.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 83 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 142
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 143 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 202
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 247
>AL360170-1|CAH70403.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 83 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 142
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 143 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 202
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 247
>AL356423-3|CAI13115.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 91 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 150
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 151 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 210
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 211 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 256
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 257 KEPSFRPTAKELLK 270
>AL356423-2|CAI13114.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 103 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 162
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 163 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 222
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 223 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 268
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 269 KEPSFRPTAKELLK 282
>AL356423-1|CAI13113.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 8 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 67
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 68 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 127
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 128 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 173
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 174 KEPSFRPTAKELLK 187
>AL354932-1|CAI11034.2| 651|Homo sapiens maternal embryonic leucine
zipper kinase protein.
Length = 651
Score = 67.3 bits (157), Expect = 2e-10
Identities = 41/149 (27%), Positives = 71/149 (47%), Gaps = 7/149 (4%)
Query: 45 QRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVAN 101
+ L ++ H ++C ++ ++ +V+ G L D + +LS EE V RQ+ +
Sbjct: 59 EALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVS 118
Query: 102 GLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP--LGQPRYLSPE 159
+ Y+H+ HR L +N+L D K+KL ++G+ G + G Y +PE
Sbjct: 119 AVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPE 178
Query: 160 TILNSG--GPTADIWTFGVILLELCIGKL 186
I G AD+W+ G++L L G L
Sbjct: 179 LIQGKSYLGSEADVWSMGILLYVLMCGFL 207
>AL138761-2|CAI12395.1| 1235|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1235
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 83 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 142
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 143 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 202
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 247
>AL138761-1|CAI12396.1| 1204|Homo sapiens Ste20-related
serine\/threonine kinase (SLK) protein.
Length = 1204
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 83 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 142
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 143 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 202
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 247
>AL137249-7|CAI39457.1| 431|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 431
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 91 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 150
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 151 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 210
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 211 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 256
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 257 KEPSFRPTAKELLK 270
>AL137249-3|CAI39453.1| 443|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 443
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 103 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 162
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 163 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 222
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 223 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 268
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 269 KEPSFRPTAKELLK 282
>AL137249-2|CAI39452.1| 368|Homo sapiens serine/threonine kinase 24
(STE20 homolog, yeast) protein.
Length = 368
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 8 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 67
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 68 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 127
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 128 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 173
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 174 KEPSFRPTAKELLK 187
>AK222811-1|BAD96531.1| 651|Homo sapiens maternal embryonic leucine
zipper kinase variant protein.
Length = 651
Score = 67.3 bits (157), Expect = 2e-10
Identities = 41/149 (27%), Positives = 71/149 (47%), Gaps = 7/149 (4%)
Query: 45 QRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADL---KKKLSTEEIINVARQVAN 101
+ L ++ H ++C ++ ++ +V+ G L D + +LS EE V RQ+ +
Sbjct: 59 EALKNLRHQHICQLYHVLETANKIFMVLEYCPGGELFDYIISQDRLSEEETRVVFRQIVS 118
Query: 102 GLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFP--LGQPRYLSPE 159
+ Y+H+ HR L +N+L D K+KL ++G+ G + G Y +PE
Sbjct: 119 AVAYVHSQGYAHRDLKPENLLFDEYHKLKLIDFGLCAKPKGNKDYHLQTCCGSLAYAAPE 178
Query: 160 TILNSG--GPTADIWTFGVILLELCIGKL 186
I G AD+W+ G++L L G L
Sbjct: 179 LIQGKSYLGSEADVWSMGILLYVLMCGFL 207
>AF273048-1|AAG34908.1| 1235|Homo sapiens CTCL tumor antigen se20-9
protein.
Length = 1235
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 83 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 142
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 143 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 202
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 247
>AF083420-1|AAD42039.1| 443|Homo sapiens brain-specific STE20-like
protein kinase 3 protein.
Length = 443
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 103 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 162
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 163 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 222
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 223 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 268
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 269 KEPSFRPTAKELLK 282
>AF024636-1|AAB82560.1| 431|Homo sapiens STE20-like kinase 3
protein.
Length = 431
Score = 67.3 bits (157), Expect = 2e-10
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 20/194 (10%)
Query: 65 KHERIIVVAEVIGKSLA-DLKKK--LSTEEIINVARQVANGLQYLHANNITHRTLSDDNI 121
K ++ ++ E +G A DL + L +I + R++ GL YLH+ HR + N+
Sbjct: 91 KDTKLWIIMEYLGGGSALDLLEPGPLDETQIATILREILKGLDYLHSEKKIHRDIKAANV 150
Query: 122 LIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSPETILNSG-GPTADIWTFGVILL 179
L+ +G+VKL ++G+ +T + +G P +++PE I S ADIW+ G+ +
Sbjct: 151 LLSEHGEVKLADFGVAGQLTDTQIKRNTFVGTPFWMAPEVIKQSAYDSKADIWSLGITAI 210
Query: 180 ELCIGK-LWAKLKPGPILRRILGLVHVNDPAKRIAREHNSIEEYEQLPKYLQTLIEKCLQ 238
EL G+ ++L P ++L L+ N+P E N K L+ +E CL
Sbjct: 211 ELARGEPPHSELHP----MKVLFLIPKNNPP---TLEGN-------YSKPLKEFVEACLN 256
Query: 239 ICPSKRATITEILQ 252
PS R T E+L+
Sbjct: 257 KEPSFRPTAKELLK 270
>AB002804-1|BAA19655.1| 1204|Homo sapiens hSLK protein.
Length = 1204
Score = 67.3 bits (157), Expect = 2e-10
Identities = 48/165 (29%), Positives = 83/165 (50%), Gaps = 12/165 (7%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKS----LADLKKKLSTEEIINVARQVANG 102
L S +HPN+ LD ++ I++ G + + +L++ L+ +I V +Q +
Sbjct: 83 LASCDHPNIVKLLDAFYYENNLWILIEFCAGGAVDAVMLELERPLTESQIQVVCKQTLDA 142
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYM-TYGGSEVAFPLGQPRYLSPETI 161
L YLH N I HR L NIL L+G +KL ++G+ T +G P +++PE +
Sbjct: 143 LNYLHDNKIIHRDLKAGNILFTLDGDIKLADFGVSAKNTRTIQRRDSFIGTPYWMAPEVV 202
Query: 162 L---NSGGP---TADIWTFGVILLELC-IGKLWAKLKPGPILRRI 199
+ + P AD+W+ G+ L+E+ I +L P +L +I
Sbjct: 203 MCETSKDRPYDYKADVWSLGITLIEMAEIEPPHHELNPMRVLLKI 247
>AK074578-1|BAC11070.1| 426|Homo sapiens protein ( Homo sapiens
cDNA FLJ90097 fis, clone HEMBA1005929, weakly similar to
H.sapiens mRNA for serine/threonine protein kinase EMK.
).
Length = 426
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/159 (27%), Positives = 76/159 (47%), Gaps = 16/159 (10%)
Query: 97 RQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYL 156
RQ+ + + Y H NI HR L +N+L+D +K+ ++G GS++ G P Y
Sbjct: 29 RQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYA 88
Query: 157 SPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAR 214
+PE GP DIW+ GVIL L G L P ++ + +R+ R
Sbjct: 89 APELFQGKKYDGPEVDIWSLGVILYTLVSGSL-------PFDGH-----NLKELRERVLR 136
Query: 215 EHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ Y + ++++ + L + P+KR T+ +I++D
Sbjct: 137 GKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKD 173
>AC005581-1|AAC33487.1| 462|Homo sapiens R31237_1, partial CDS
protein.
Length = 462
Score = 66.9 bits (156), Expect = 3e-10
Identities = 44/159 (27%), Positives = 76/159 (47%), Gaps = 16/159 (10%)
Query: 97 RQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYL 156
RQ+ + + Y H NI HR L +N+L+D +K+ ++G GS++ G P Y
Sbjct: 193 RQIVSAVHYCHQKNIVHRDLKAENLLLDAEANIKIADFGFSNEFTLGSKLDTFCGSPPYA 252
Query: 157 SPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAR 214
+PE GP DIW+ GVIL L G L P ++ + +R+ R
Sbjct: 253 APELFQGKKYDGPEVDIWSLGVILYTLVSGSL-------PFDGH-----NLKELRERVLR 300
Query: 215 EHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEILQD 253
+ Y + ++++ + L + P+KR T+ +I++D
Sbjct: 301 GKYRVPFY--MSTDCESILRRFLVLNPAKRCTLEQIMKD 337
>X66365-1|CAA47008.1| 326|Homo sapiens serine/threonine protein
kinase protein.
Length = 326
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/165 (27%), Positives = 81/165 (49%), Gaps = 12/165 (7%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDIIR----GKHERIIVVAEVIGKSLAD 82
G G+PL S+I + + L + EHPN+ D+ + ++ +V E + + L
Sbjct: 50 GEEGMPL--STIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTT 107
Query: 83 LKKKLS-----TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K+ TE I ++ Q+ GL +LH++ + HR L NIL+ +G++KL ++G+
Sbjct: 108 YLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLA 167
Query: 138 YMTYGGSEVAFPLGQPRYLSPETILNSGGPT-ADIWTFGVILLEL 181
+ + + Y +PE +L S T D+W+ G I E+
Sbjct: 168 RIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEM 212
>L07032-1|AAA60101.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 7/148 (4%)
Query: 45 QRLLSI--EHPNLCTYLDIIRGKHERIIVVAEVIGKSLA---DLKKKLSTEEIINVARQV 99
+R+LS+ EHP L + K V+ + G L K A ++
Sbjct: 429 KRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 488
Query: 100 ANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMT-YGGSEVAFPLGQPRYLSP 158
GLQ+LH+ I +R L DNIL+D +G +K+ ++G+ G ++ G P Y++P
Sbjct: 489 ILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 548
Query: 159 ETILNSG-GPTADIWTFGVILLELCIGK 185
E +L + D W+FGV+L E+ IG+
Sbjct: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQ 576
>L01087-1|AAA75571.1| 706|Homo sapiens protein kinase C-theta
protein.
Length = 706
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 7/148 (4%)
Query: 45 QRLLSI--EHPNLCTYLDIIRGKHERIIVVAEVIGKSLA---DLKKKLSTEEIINVARQV 99
+R+LS+ EHP L + K V+ + G L K A ++
Sbjct: 429 KRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 488
Query: 100 ANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMT-YGGSEVAFPLGQPRYLSP 158
GLQ+LH+ I +R L DNIL+D +G +K+ ++G+ G ++ G P Y++P
Sbjct: 489 ILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 548
Query: 159 ETILNSG-GPTADIWTFGVILLELCIGK 185
E +L + D W+FGV+L E+ IG+
Sbjct: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQ 576
>BC117183-1|AAI17184.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 66.5 bits (155), Expect = 3e-10
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 19/216 (8%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKK---KLSTEEIINVA 96
I Q + ++HP++ ++ K +V + D +L+ E
Sbjct: 64 IYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKF 123
Query: 97 RQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYL 156
Q+ + + Y H I HR L +N+L+D N +K+ ++G G +A G P Y
Sbjct: 124 WQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYA 183
Query: 157 SPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAR 214
+PE GP DIW+ GV+L L G L PILR +R+
Sbjct: 184 APEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILR------------QRVLE 231
Query: 215 EHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
I + + + + LI + L + PSKR TI +I
Sbjct: 232 GRFRIPYF--MSEDCEHLIRRMLVLDPSKRLTIAQI 265
>BC113459-1|AAI13460.1| 926|Homo sapiens SNF1-like kinase 2
protein.
Length = 926
Score = 66.5 bits (155), Expect = 3e-10
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 19/216 (8%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKK---KLSTEEIINVA 96
I Q + ++HP++ ++ K +V + D +L+ E
Sbjct: 64 IYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKF 123
Query: 97 RQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYL 156
Q+ + + Y H I HR L +N+L+D N +K+ ++G G +A G P Y
Sbjct: 124 WQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYA 183
Query: 157 SPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAR 214
+PE GP DIW+ GV+L L G L PILR +R+
Sbjct: 184 APEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILR------------QRVLE 231
Query: 215 EHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
I + + + + LI + L + PSKR TI +I
Sbjct: 232 GRFRIPYF--MSEDCEHLIRRMLVLDPSKRLTIAQI 265
>BC113359-1|AAI13360.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 7/148 (4%)
Query: 45 QRLLSI--EHPNLCTYLDIIRGKHERIIVVAEVIGKSLA---DLKKKLSTEEIINVARQV 99
+R+LS+ EHP L + K V+ + G L K A ++
Sbjct: 429 KRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 488
Query: 100 ANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMT-YGGSEVAFPLGQPRYLSP 158
GLQ+LH+ I +R L DNIL+D +G +K+ ++G+ G ++ G P Y++P
Sbjct: 489 ILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 548
Query: 159 ETILNSG-GPTADIWTFGVILLELCIGK 185
E +L + D W+FGV+L E+ IG+
Sbjct: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQ 576
>BC101465-1|AAI01466.1| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 7/148 (4%)
Query: 45 QRLLSI--EHPNLCTYLDIIRGKHERIIVVAEVIGKSLA---DLKKKLSTEEIINVARQV 99
+R+LS+ EHP L + K V+ + G L K A ++
Sbjct: 429 KRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 488
Query: 100 ANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMT-YGGSEVAFPLGQPRYLSP 158
GLQ+LH+ I +R L DNIL+D +G +K+ ++G+ G ++ G P Y++P
Sbjct: 489 ILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 548
Query: 159 ETILNSG-GPTADIWTFGVILLELCIGK 185
E +L + D W+FGV+L E+ IG+
Sbjct: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQ 576
>BC063885-1|AAH63885.1| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 66.5 bits (155), Expect = 3e-10
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 14/147 (9%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKL--------STEEIINVARQ 98
L ++HPN+ + + + ++ R+ +V E DL K++ S ++I+ Q
Sbjct: 55 LEKMKHPNIVAFFNSFQ-ENGRLFIVMEYCDGG--DLMKRINRQRGVLFSEDQILGWFVQ 111
Query: 99 VANGLQYLHANNITHRTLSDDNILIDLNGKV-KLFNYGIFYMTYGGSEVAFP-LGQPRYL 156
++ GL+++H I HR + NI + NG V KL ++GI + E+A +G P YL
Sbjct: 112 ISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYYL 171
Query: 157 SPETILNSG-GPTADIWTFGVILLELC 182
SPE N DIW+ G +L ELC
Sbjct: 172 SPEICQNKPYNNKTDIWSLGCVLYELC 198
>BC052264-1|AAH52264.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/165 (27%), Positives = 81/165 (49%), Gaps = 12/165 (7%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDIIR----GKHERIIVVAEVIGKSLAD 82
G G+PL S+I + + L + EHPN+ D+ + ++ +V E + + L
Sbjct: 50 GEEGMPL--STIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTT 107
Query: 83 LKKKLS-----TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K+ TE I ++ Q+ GL +LH++ + HR L NIL+ +G++KL ++G+
Sbjct: 108 YLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLA 167
Query: 138 YMTYGGSEVAFPLGQPRYLSPETILNSGGPT-ADIWTFGVILLEL 181
+ + + Y +PE +L S T D+W+ G I E+
Sbjct: 168 RIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEM 212
>AY128534-1|AAM76970.1| 326|Homo sapiens cyclin-dependent kinase 6
protein.
Length = 326
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/165 (27%), Positives = 81/165 (49%), Gaps = 12/165 (7%)
Query: 27 GSNGLPLTPSSISILGRAQRLLSIEHPNLCTYLDIIR----GKHERIIVVAEVIGKSLAD 82
G G+PL S+I + + L + EHPN+ D+ + ++ +V E + + L
Sbjct: 50 GEEGMPL--STIREVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTT 107
Query: 83 LKKKLS-----TEEIINVARQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF 137
K+ TE I ++ Q+ GL +LH++ + HR L NIL+ +G++KL ++G+
Sbjct: 108 YLDKVPEPGVPTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLA 167
Query: 138 YMTYGGSEVAFPLGQPRYLSPETILNSGGPT-ADIWTFGVILLEL 181
+ + + Y +PE +L S T D+W+ G I E+
Sbjct: 168 RIYSFQMALTSVVVTLWYRAPEVLLQSSYATPVDLWSVGCIFAEM 212
>AL158043-2|CAC12904.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 7/148 (4%)
Query: 45 QRLLSI--EHPNLCTYLDIIRGKHERIIVVAEVIGKSLA---DLKKKLSTEEIINVARQV 99
+R+LS+ EHP L + K V+ + G L K A ++
Sbjct: 429 KRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 488
Query: 100 ANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMT-YGGSEVAFPLGQPRYLSP 158
GLQ+LH+ I +R L DNIL+D +G +K+ ++G+ G ++ G P Y++P
Sbjct: 489 ILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 548
Query: 159 ETILNSG-GPTADIWTFGVILLELCIGK 185
E +L + D W+FGV+L E+ IG+
Sbjct: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQ 576
>AL158043-1|CAI16127.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 7/148 (4%)
Query: 45 QRLLSI--EHPNLCTYLDIIRGKHERIIVVAEVIGKSLA---DLKKKLSTEEIINVARQV 99
+R+LS+ EHP L + K V+ + G L K A ++
Sbjct: 201 KRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 260
Query: 100 ANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMT-YGGSEVAFPLGQPRYLSP 158
GLQ+LH+ I +R L DNIL+D +G +K+ ++G+ G ++ G P Y++P
Sbjct: 261 ILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 320
Query: 159 ETILNSG-GPTADIWTFGVILLELCIGK 185
E +L + D W+FGV+L E+ IG+
Sbjct: 321 EILLGQKYNHSVDWWSFGVLLYEMLIGQ 348
>AL139082-5|CAI12892.2| 708|Homo sapiens NIMA (never in mitosis
gene a)-related kinase 5 protein.
Length = 708
Score = 66.5 bits (155), Expect = 3e-10
Identities = 46/147 (31%), Positives = 75/147 (51%), Gaps = 14/147 (9%)
Query: 47 LLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKKL--------STEEIINVARQ 98
L ++HPN+ + + + ++ R+ +V E DL K++ S ++I+ Q
Sbjct: 55 LEKMKHPNIVAFFNSFQ-ENGRLFIVMEYCDGG--DLMKRINRQRGVLFSEDQILGWFVQ 111
Query: 99 VANGLQYLHANNITHRTLSDDNILIDLNGKV-KLFNYGIFYMTYGGSEVAFP-LGQPRYL 156
++ GL+++H I HR + NI + NG V KL ++GI + E+A +G P YL
Sbjct: 112 ISLGLKHIHDRKILHRDIKAQNIFLSKNGMVAKLGDFGIARVLNNSMELARTCIGTPYYL 171
Query: 157 SPETILNSG-GPTADIWTFGVILLELC 182
SPE N DIW+ G +L ELC
Sbjct: 172 SPEICQNKPYNNKTDIWSLGCVLYELC 198
>AL137145-2|CAC10200.2| 706|Homo sapiens protein kinase C, theta
protein.
Length = 706
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 7/148 (4%)
Query: 45 QRLLSI--EHPNLCTYLDIIRGKHERIIVVAEVIGKSLA---DLKKKLSTEEIINVARQV 99
+R+LS+ EHP L + K V+ + G L K A ++
Sbjct: 429 KRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 488
Query: 100 ANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMT-YGGSEVAFPLGQPRYLSP 158
GLQ+LH+ I +R L DNIL+D +G +K+ ++G+ G ++ G P Y++P
Sbjct: 489 ILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 548
Query: 159 ETILNSG-GPTADIWTFGVILLELCIGK 185
E +L + D W+FGV+L E+ IG+
Sbjct: 549 EILLGQKYNHSVDWWSFGVLLYEMLIGQ 576
>AL137145-1|CAI15756.1| 478|Homo sapiens protein kinase C, theta
protein.
Length = 478
Score = 66.5 bits (155), Expect = 3e-10
Identities = 45/148 (30%), Positives = 73/148 (49%), Gaps = 7/148 (4%)
Query: 45 QRLLSI--EHPNLCTYLDIIRGKHERIIVVAEVIGKSLA---DLKKKLSTEEIINVARQV 99
+R+LS+ EHP L + K V+ + G L K A ++
Sbjct: 201 KRVLSLAWEHPFLTHMFCTFQTKENLFFVMEYLNGGDLMYHIQSCHKFDLSRATFYAAEI 260
Query: 100 ANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMT-YGGSEVAFPLGQPRYLSP 158
GLQ+LH+ I +R L DNIL+D +G +K+ ++G+ G ++ G P Y++P
Sbjct: 261 ILGLQFLHSKGIVYRDLKLDNILLDKDGHIKIADFGMCKENMLGDAKTNTFCGTPDYIAP 320
Query: 159 ETILNSG-GPTADIWTFGVILLELCIGK 185
E +L + D W+FGV+L E+ IG+
Sbjct: 321 EILLGQKYNHSVDWWSFGVLLYEMLIGQ 348
>AB084424-1|BAB91442.1| 346|Homo sapiens KIAA0781 protein protein.
Length = 346
Score = 66.5 bits (155), Expect = 3e-10
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 19/216 (8%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKK---KLSTEEIINVA 96
I Q + ++HP++ ++ K +V + D +L+ E
Sbjct: 62 IYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKF 121
Query: 97 RQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYL 156
Q+ + + Y H I HR L +N+L+D N +K+ ++G G +A G P Y
Sbjct: 122 WQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYA 181
Query: 157 SPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAR 214
+PE GP DIW+ GV+L L G L PILR +R+
Sbjct: 182 APEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILR------------QRVLE 229
Query: 215 EHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
I + + + + LI + L + PSKR TI +I
Sbjct: 230 GRFRIPYF--MSEDCEHLIRRMLVLDPSKRLTIAQI 263
>AB018324-1|BAA34501.3| 950|Homo sapiens KIAA0781 protein protein.
Length = 950
Score = 66.5 bits (155), Expect = 3e-10
Identities = 56/216 (25%), Positives = 90/216 (41%), Gaps = 19/216 (8%)
Query: 40 ILGRAQRLLSIEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKK---KLSTEEIINVA 96
I Q + ++HP++ ++ K +V + D +L+ E
Sbjct: 88 IYREVQIMKMLDHPHIIKLYQVMETKSMLYLVTEYAKNGEIFDYLANHGRLNESEARRKF 147
Query: 97 RQVANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGGSEVAFPLGQPRYL 156
Q+ + + Y H I HR L +N+L+D N +K+ ++G G +A G P Y
Sbjct: 148 WQILSAVDYCHGRKIVHRDLKAENLLLDNNMNIKIADFGFGNFFKSGELLATWCGSPPYA 207
Query: 157 SPETILNS--GGPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAR 214
+PE GP DIW+ GV+L L G L PILR +R+
Sbjct: 208 APEVFEGQQYEGPQLDIWSMGVVLYVLVCGALPFDGPTLPILR------------QRVLE 255
Query: 215 EHNSIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
I + + + + LI + L + PSKR TI +I
Sbjct: 256 GRFRIPYF--MSEDCEHLIRRMLVLDPSKRLTIAQI 289
>BC078179-1|AAH78179.1| 616|Homo sapiens EIF2AK4 protein protein.
Length = 616
Score = 66.1 bits (154), Expect = 4e-10
Identities = 43/147 (29%), Positives = 74/147 (50%), Gaps = 9/147 (6%)
Query: 47 LLSIEHPNLCTYLDI-IRGKHERIIV---VAEVIGKSLA---DLKKKLSTEEIINVARQV 99
L+ + HPN+ YL + ++ + + I+V V + G SLA + ++ Q+
Sbjct: 350 LVKLSHPNVVRYLAMNLKEQDDSIVVDILVEHISGVSLAAHLSHSGPIPVHQLRRYTAQL 409
Query: 100 ANGLQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIF-YMTYGGSEVAFPLGQPRYLSP 158
+GL YLH+N++ H+ LS N+L+D G VK+ +Y I + E F + R+ S
Sbjct: 410 LSGLDYLHSNSVVHKVLSASNVLVDAEGTVKITDYSISKRLADICKEDVFEQTRVRF-SD 468
Query: 159 ETILNSGGPTADIWTFGVILLELCIGK 185
+ G D+W G++LL L G+
Sbjct: 469 NALPYKTGKKGDVWRLGLLLLSLSQGQ 495
>BC043487-1|AAH43487.1| 505|Homo sapiens
calcium/calmodulin-dependent protein kinase kinase 1,
alpha protein.
Length = 505
Score = 66.1 bits (154), Expect = 4e-10
Identities = 54/213 (25%), Positives = 96/213 (45%), Gaps = 21/213 (9%)
Query: 47 LLSIEHPNLCTYLDIIRGKHE-RIIVVAEVIGKSLA---DLKKKLSTEEIINVARQVANG 102
L ++H N+ ++++ E + +V +++ K K S E+ R V G
Sbjct: 203 LKKLDHVNVVKLIEVLDDPAEDNLYLVFDLLRKGPVMEVPCDKPFSEEQARLYLRDVILG 262
Query: 103 LQYLHANNITHRTLSDDNILIDLNGKVKLFNYGIFYMTYGG-SEVAFPLGQPRYLSPETI 161
L+YLH I HR + N+L+ +G VK+ ++G+ G ++++ G P +++PE I
Sbjct: 263 LEYLHCQKIVHRDIKPSNLLLGDDGHVKIADFGVSNQFEGNDAQLSSTAGTPAFMAPEAI 322
Query: 162 LNSG----GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHN 217
+SG G D+W GV L GK P + + +H ++I E
Sbjct: 323 SDSGQSFSGKALDVWATGVTLYCFVYGKC-------PFIDDFILALH-----RKIKNEPV 370
Query: 218 SIEEYEQLPKYLQTLIEKCLQICPSKRATITEI 250
E ++ + L+ LI K L P R + +I
Sbjct: 371 VFPEEPEISEELKDLILKMLDKNPETRIGVPDI 403
>AL732423-2|CAM17479.1| 748|Homo sapiens mitogen-activated protein
kinase kinase kinase 15 protein.
Length = 748
Score = 66.1 bits (154), Expect = 4e-10
Identities = 69/241 (28%), Positives = 106/241 (43%), Gaps = 26/241 (10%)
Query: 50 IEHPNLCTYLDIIRGKHERIIVVAEVIGKSLADLKKK----LSTEEIINVARQVANGLQY 105
++H N+ YL + I + +V G SL+ L + + I +Q+ GL+Y
Sbjct: 139 LKHRNIVQYLGSVSENGYIKIFMEQVPGGSLSALLRSKWGPMKEPTIKFYTKQILEGLKY 198
Query: 106 LHANNITHRTLSDDNILID-LNGKVKLFNYGIFYMTYGGSEVAFPL-GQPRYLSPETILN 163
LH N I HR + DN+L++ +G VK+ ++G G + G +Y++PE I++
Sbjct: 199 LHENQIVHRDIKGDNVLVNTYSGVVKISDFGTSKRLAGVNPCTETFTGTLQYMAPE-IID 257
Query: 164 SG----GPTADIWTFGVILLELCIGKLWAKLKPGPILRRILGLVHVNDPAKRIAREHNSI 219
G G ADIW+ G ++E+ A KP P LG + + H I
Sbjct: 258 QGPRGYGAPADIWSLGCTIIEM------ATSKP-PF--HELGEPQAAMFKVGMFKIHPEI 308
Query: 220 EEYEQLPKYLQTLIEKCLQICPSKRATITEILQD----LSNVDTKEMCAVKPPRGLMGCK 275
E L + I C + P KRAT E+L++ N K A KP G G
Sbjct: 309 P--EALSAEARAFILSCFEPDPHKRATTAELLREGFLRQVNKGKKNRIAFKPSEGPRGVV 366
Query: 276 L 276
L
Sbjct: 367 L 367
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.324 0.140 0.436
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 121,006,622
Number of Sequences: 224733
Number of extensions: 5582822
Number of successful extensions: 14628
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1984
Number of HSP's successfully gapped in prelim test: 698
Number of HSP's that attempted gapping in prelim test: 9903
Number of HSP's gapped (non-prelim): 3271
length of query: 766
length of database: 73,234,838
effective HSP length: 96
effective length of query: 670
effective length of database: 51,660,470
effective search space: 34612514900
effective search space used: 34612514900
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (22.0 bits)
S2: 69 (31.9 bits)
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