Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000868-TA|BGIBMGA000868-PA|IPR001128|Cytochrome P450,
IPR002401|E-class P450, group I
(146 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 125 7e-29
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 125 7e-29
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 125 7e-29
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 125 7e-29
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 113 2e-25
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 111 7e-25
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 111 1e-24
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 111 1e-24
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 111 1e-24
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 111 1e-24
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 111 1e-24
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 110 2e-24
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 110 2e-24
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 109 3e-24
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 109 3e-24
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 109 3e-24
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 109 5e-24
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 109 5e-24
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 109 5e-24
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 109 5e-24
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 107 1e-23
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 107 1e-23
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 107 1e-23
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 107 1e-23
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 107 1e-23
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 107 1e-23
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 104 1e-22
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 104 1e-22
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 104 1e-22
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 104 1e-22
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 104 1e-22
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 104 1e-22
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 104 1e-22
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 104 1e-22
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 104 1e-22
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 104 1e-22
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 104 1e-22
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 104 1e-22
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 104 1e-22
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 103 2e-22
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 103 2e-22
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 103 2e-22
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 103 2e-22
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 103 2e-22
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 103 2e-22
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 103 2e-22
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 103 2e-22
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 103 2e-22
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 103 2e-22
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 103 2e-22
AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 103 2e-22
AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 103 2e-22
AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 103 2e-22
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 103 2e-22
AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 103 2e-22
AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 103 2e-22
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 103 2e-22
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 103 2e-22
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 103 2e-22
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 103 2e-22
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 103 2e-22
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 103 2e-22
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 103 2e-22
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 103 2e-22
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 101 7e-22
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 101 7e-22
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 101 7e-22
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 101 7e-22
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 101 7e-22
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 101 7e-22
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 100 4e-21
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 99 5e-21
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 99 5e-21
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 99 5e-21
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 99 5e-21
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 98 9e-21
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 98 9e-21
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 98 9e-21
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 98 9e-21
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 98 1e-20
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 97 3e-20
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 97 3e-20
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 95 6e-20
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 95 1e-19
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 95 1e-19
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 95 1e-19
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 95 1e-19
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 95 1e-19
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 95 1e-19
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 95 1e-19
AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, famil... 94 2e-19
AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family... 94 2e-19
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 94 2e-19
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 93 3e-19
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 93 3e-19
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 93 3e-19
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 93 3e-19
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 93 3e-19
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 93 3e-19
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 93 3e-19
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 93 3e-19
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 93 3e-19
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 92 8e-19
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 92 8e-19
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 85 1e-16
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 85 1e-16
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 84 2e-16
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 84 2e-16
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 84 2e-16
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 84 2e-16
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 84 2e-16
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 83 5e-16
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 82 8e-16
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 82 8e-16
AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 82 8e-16
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 82 8e-16
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 81 1e-15
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 80 3e-15
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 80 3e-15
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 80 3e-15
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 80 3e-15
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 80 3e-15
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 78 1e-14
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 78 1e-14
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 78 1e-14
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 78 1e-14
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 78 1e-14
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 78 1e-14
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 78 1e-14
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 78 1e-14
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 78 1e-14
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 78 1e-14
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 78 1e-14
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 78 1e-14
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 78 1e-14
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 78 1e-14
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 78 1e-14
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 78 1e-14
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 78 1e-14
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 78 1e-14
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 78 1e-14
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 78 1e-14
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 74 2e-13
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 74 2e-13
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 74 2e-13
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 74 2e-13
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 74 2e-13
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 74 2e-13
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 74 2e-13
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 74 2e-13
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 74 2e-13
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 72 7e-13
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 72 9e-13
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 72 9e-13
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 72 9e-13
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 72 9e-13
BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 72 9e-13
BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 72 9e-13
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 72 9e-13
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 72 9e-13
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 72 9e-13
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 72 9e-13
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 72 9e-13
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 72 9e-13
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 72 9e-13
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 72 9e-13
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 72 9e-13
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 72 9e-13
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 72 9e-13
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 72 9e-13
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 72 9e-13
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 72 9e-13
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 72 9e-13
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 72 9e-13
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 72 9e-13
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 72 9e-13
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 72 9e-13
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 71 1e-12
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 71 1e-12
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 71 1e-12
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 71 1e-12
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 71 1e-12
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 71 1e-12
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 71 1e-12
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 71 1e-12
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 71 1e-12
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 71 1e-12
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 71 1e-12
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 71 1e-12
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 71 1e-12
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 71 1e-12
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 71 1e-12
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 71 1e-12
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 71 1e-12
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 71 1e-12
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 71 1e-12
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 71 2e-12
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 71 2e-12
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 71 2e-12
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 70 3e-12
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 69 8e-12
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 68 1e-11
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 68 1e-11
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 66 3e-11
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 66 3e-11
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 66 3e-11
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 66 3e-11
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 66 3e-11
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 66 3e-11
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 66 3e-11
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 66 3e-11
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 66 6e-11
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 65 8e-11
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 65 8e-11
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 65 8e-11
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 65 8e-11
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 65 8e-11
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 65 8e-11
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 65 8e-11
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 65 8e-11
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 65 8e-11
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 65 8e-11
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 65 8e-11
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 65 1e-10
BC128535-1|AAI28536.1| 143|Homo sapiens LOC283480 protein protein. 64 1e-10
BC039307-1|AAH39307.1| 372|Homo sapiens FLJ16008 protein protein. 64 2e-10
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 64 2e-10
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 64 2e-10
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 64 2e-10
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 64 2e-10
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 64 2e-10
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 63 4e-10
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 62 5e-10
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 62 5e-10
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 62 7e-10
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 62 7e-10
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 62 7e-10
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 62 7e-10
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 62 9e-10
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 60 2e-09
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 60 2e-09
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 60 2e-09
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 60 2e-09
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 60 2e-09
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 60 2e-09
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 60 3e-09
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 60 4e-09
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 60 4e-09
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 60 4e-09
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 60 4e-09
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 60 4e-09
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 60 4e-09
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 60 4e-09
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 60 4e-09
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 60 4e-09
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 60 4e-09
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 60 4e-09
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 60 4e-09
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 60 4e-09
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 60 4e-09
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 60 4e-09
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 59 7e-09
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 59 7e-09
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 59 7e-09
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 58 9e-09
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 58 2e-08
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 57 2e-08
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 57 3e-08
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 57 3e-08
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 57 3e-08
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 57 3e-08
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 57 3e-08
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 57 3e-08
AC005336-2|AAC27731.1| 93|Homo sapiens F20191_1, partial CDS p... 57 3e-08
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 56 4e-08
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 56 4e-08
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 56 4e-08
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 56 4e-08
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 56 5e-08
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 55 8e-08
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 55 1e-07
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 55 1e-07
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 55 1e-07
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 55 1e-07
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 55 1e-07
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 55 1e-07
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 54 2e-07
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 54 2e-07
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 54 2e-07
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 54 2e-07
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 54 2e-07
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 54 2e-07
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 54 2e-07
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 54 2e-07
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 54 2e-07
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 54 2e-07
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 54 2e-07
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 54 2e-07
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 54 2e-07
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 54 2e-07
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 54 2e-07
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 54 2e-07
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 54 2e-07
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 54 2e-07
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 54 2e-07
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 54 2e-07
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 54 2e-07
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 54 2e-07
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 53 3e-07
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 53 3e-07
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 53 4e-07
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 52 8e-07
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 52 1e-06
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 52 1e-06
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 52 1e-06
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 52 1e-06
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 52 1e-06
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 52 1e-06
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 52 1e-06
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 52 1e-06
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 52 1e-06
AF176805-1|AAK11850.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 52 1e-06
AF127090-1|AAD20021.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 52 1e-06
AF029403-1|AAC95426.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 52 1e-06
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 51 1e-06
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 51 2e-06
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 51 2e-06
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 51 2e-06
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 51 2e-06
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 51 2e-06
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 51 2e-06
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 51 2e-06
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 51 2e-06
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 50 2e-06
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 50 2e-06
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 50 2e-06
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 50 2e-06
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 50 2e-06
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 50 2e-06
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 50 2e-06
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 50 2e-06
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 50 2e-06
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 50 2e-06
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 50 4e-06
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 50 4e-06
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 50 4e-06
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 50 4e-06
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 50 4e-06
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 50 4e-06
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 50 4e-06
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 50 4e-06
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 50 4e-06
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 50 4e-06
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 50 4e-06
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 49 5e-06
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 48 9e-06
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 48 1e-05
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 48 2e-05
U03688-1|AAA19567.1| 543|Homo sapiens cytochrome P450 protein. 47 3e-05
DQ016495-1|AAY34975.1| 195|Homo sapiens cytochrome P450 1B1 pro... 47 3e-05
BT020001-1|AAV38804.1| 543|Homo sapiens cytochrome P450, family... 47 3e-05
BC012049-1|AAH12049.1| 543|Homo sapiens cytochrome P450, family... 47 3e-05
AY359068-1|AAQ89427.1| 462|Homo sapiens P450-like protein protein. 47 3e-05
AC009229-2|AAY15039.1| 543|Homo sapiens unknown protein. 47 3e-05
U56438-1|AAC50809.1| 543|Homo sapiens dioxin-inducible cytochro... 46 4e-05
AY393998-1|AAQ87875.1| 543|Homo sapiens cytochrome P450, family... 46 4e-05
AF450132-1|AAM50512.1| 543|Homo sapiens cytochrome P450 CYP1B1 ... 46 4e-05
BT019979-1|AAV38782.1| 543|Homo sapiens cytochrome P450, family... 46 7e-05
BC093022-1|AAH93022.1| 416|Homo sapiens CYP20A1 protein protein. 45 9e-05
BC033752-1|AAH33752.1| 462|Homo sapiens cytochrome P450, family... 45 9e-05
BC020616-1|AAH20616.1| 462|Homo sapiens cytochrome P450, family... 45 9e-05
AF183412-1|AAG09681.1| 435|Homo sapiens cytochrome P450 monooxy... 44 3e-04
BC029155-1|AAH29155.1| 489|Homo sapiens Unknown (protein for IM... 43 4e-04
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 42 8e-04
X56088-1|CAA39568.1| 504|Homo sapiens cholesterol 7-alpha-hydr... 41 0.002
M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha hydro... 41 0.002
BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family... 41 0.002
BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family... 41 0.002
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 38 0.017
S77873-1|AAD14267.1| 68|Homo sapiens CYP2E1 protein. 35 0.12
BC067444-1|AAH67444.1| 501|Homo sapiens cytochrome P450, family... 34 0.16
AK000366-1|BAA91114.1| 408|Homo sapiens protein ( Homo sapiens ... 34 0.22
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 33 0.38
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 33 0.38
AL138805-2|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 33 0.38
BC067442-1|AAH67442.1| 501|Homo sapiens cytochrome P450, family... 33 0.50
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 33 0.50
AF090320-1|AAD19877.1| 501|Homo sapiens sterol 12-alpha-hydroxy... 33 0.50
AF090318-1|AAC63037.1| 462|Homo sapiens sterol 12-alpha hydroxy... 33 0.50
BC067441-1|AAH67441.1| 501|Homo sapiens cytochrome P450, family... 31 1.1
BC067434-1|AAH67434.1| 501|Homo sapiens cytochrome P450, family... 31 1.1
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 31 2.0
L14721-1|AAA35522.1| 957|Homo sapiens aminopeptidase A protein. 30 3.5
L12468-1|AAA16876.1| 957|Homo sapiens aminopeptidase A protein. 30 3.5
BC094770-1|AAH94770.1| 957|Homo sapiens glutamyl aminopeptidase... 30 3.5
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 30 3.5
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 125 bits (301), Expect = 7e-29
Identities = 63/136 (46%), Positives = 92/136 (67%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ LE VIKE+LR++PSVPL R +++D EV G ++ KGT V+ + +HR+P F P
Sbjct: 378 LRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPE 437
Query: 61 EFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVD--I 116
EF PERF ++ + ++P++++ FSAGPRNCIGQKFA+ME K LS ++R+F +
Sbjct: 438 EFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKRE 497
Query: 117 EPILCADLILRSQNGV 132
E L LILR NG+
Sbjct: 498 ELGLEGQLILRPSNGI 513
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 125 bits (301), Expect = 7e-29
Identities = 63/136 (46%), Positives = 92/136 (67%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ LE VIKE+LR++PSVPL R +++D EV G ++ KGT V+ + +HR+P F P
Sbjct: 378 LRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPE 437
Query: 61 EFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVD--I 116
EF PERF ++ + ++P++++ FSAGPRNCIGQKFA+ME K LS ++R+F +
Sbjct: 438 EFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKRE 497
Query: 117 EPILCADLILRSQNGV 132
E L LILR NG+
Sbjct: 498 ELGLEGQLILRPSNGI 513
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 125 bits (301), Expect = 7e-29
Identities = 63/136 (46%), Positives = 92/136 (67%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ LE VIKE+LR++PSVPL R +++D EV G ++ KGT V+ + +HR+P F P
Sbjct: 356 LRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPE 415
Query: 61 EFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVD--I 116
EF PERF ++ + ++P++++ FSAGPRNCIGQKFA+ME K LS ++R+F +
Sbjct: 416 EFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKRE 475
Query: 117 EPILCADLILRSQNGV 132
E L LILR NG+
Sbjct: 476 ELGLEGQLILRPSNGI 491
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 125 bits (301), Expect = 7e-29
Identities = 63/136 (46%), Positives = 92/136 (67%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ LE VIKE+LR++PSVPL R +++D EV G ++ KGT V+ + +HR+P F P
Sbjct: 378 LRYLECVIKETLRLFPSVPLFARSVSEDCEVAGYRVLKGTEAVIIPYALHRDPRYFPNPE 437
Query: 61 EFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVD--I 116
EF PERF ++ + ++P++++ FSAGPRNCIGQKFA+ME K LS ++R+F +
Sbjct: 438 EFQPERFFPENAQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILSCILRHFWIESNQKRE 497
Query: 117 EPILCADLILRSQNGV 132
E L LILR NG+
Sbjct: 498 ELGLEGQLILRPSNGI 513
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 113 bits (273), Expect = 2e-25
Identities = 57/132 (43%), Positives = 88/132 (66%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + IKESLR++P VP+I R T+D + G + KG ++NI +H NP V+ P +
Sbjct: 381 LTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVY 440
Query: 63 IPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RF ++++ ++P +++ FSAGPRNCIGQ FAM EMKV L+ + +F+++P IEP
Sbjct: 441 DPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHIEPRR 500
Query: 121 CADLILRSQNGV 132
+LILR++ G+
Sbjct: 501 KPELILRAEGGL 512
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 111 bits (268), Expect = 7e-25
Identities = 56/132 (42%), Positives = 87/132 (65%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + IKESLR++P VP+I R T+D + G + KG ++NI +H NP V+ P +
Sbjct: 381 LTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVCLINIIGIHYNPTVWPDPEVY 440
Query: 63 IPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RF ++++ ++P +++ FSAGPRNCIGQ FAM EMKV L+ + +F+++P EP
Sbjct: 441 DPFRFNQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALTLLHFRILPTHTEPRR 500
Query: 121 CADLILRSQNGV 132
+LILR++ G+
Sbjct: 501 KPELILRAEGGL 512
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 111 bits (266), Expect = 1e-24
Identities = 54/132 (40%), Positives = 87/132 (65%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P VP+I R +T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L+ + F+++P EP
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 111 bits (266), Expect = 1e-24
Identities = 54/132 (40%), Positives = 87/132 (65%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P VP+I R +T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L+ + F+++P EP
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 111 bits (266), Expect = 1e-24
Identities = 54/132 (40%), Positives = 87/132 (65%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P VP+I R +T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L+ + F+++P EP
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 111 bits (266), Expect = 1e-24
Identities = 54/132 (40%), Positives = 87/132 (65%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P VP+I R +T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L+ + F+++P EP
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 111 bits (266), Expect = 1e-24
Identities = 54/132 (40%), Positives = 87/132 (65%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P VP+I R +T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L+ + F+++P EP
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 110 bits (265), Expect = 2e-24
Identities = 54/132 (40%), Positives = 87/132 (65%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P VP+I R +T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCMKESLRVHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L+ + F+++P EP
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 110 bits (265), Expect = 2e-24
Identities = 54/132 (40%), Positives = 84/132 (63%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + IKESLR++P VP + R T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L + F+++P EP
Sbjct: 441 DPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGI 512
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 109 bits (263), Expect = 3e-24
Identities = 53/132 (40%), Positives = 87/132 (65%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P VP+I R +T+D + G + KG ++++F H NP ++ P +
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAMWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L+ + F+++P EP
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 109 bits (263), Expect = 3e-24
Identities = 54/132 (40%), Positives = 84/132 (63%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + IKESLR++P VP + R T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L + F+++P EP
Sbjct: 441 DPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLRFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 109 bits (263), Expect = 3e-24
Identities = 53/132 (40%), Positives = 87/132 (65%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P VP+I R +T+D + G + KG ++++F H NP ++ P +
Sbjct: 381 LTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIICLISVFGTHHNPAMWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L+ + F+++P EP
Sbjct: 441 DPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKVVLALTLLRFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 109 bits (261), Expect = 5e-24
Identities = 54/132 (40%), Positives = 84/132 (63%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + IKESLR++P VP + R T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L + F+++P EP
Sbjct: 441 DPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 109 bits (261), Expect = 5e-24
Identities = 53/132 (40%), Positives = 85/132 (64%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLK-LSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P +P R T+D + + + KG +NIF +H NP V+ P +
Sbjct: 381 LTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVCNINIFAIHHNPSVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD + + ++P +++ FSAGPRNCIGQKFAM EMKV L+ + F+++P EP
Sbjct: 441 DPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKVVLALTLLRFRILPDHREPRR 500
Query: 121 CADLILRSQNGV 132
+++LR+++G+
Sbjct: 501 TPEIVLRAEDGL 512
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 109 bits (261), Expect = 5e-24
Identities = 54/132 (40%), Positives = 84/132 (63%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + IKESLR++P VP + R T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L + F+++P EP
Sbjct: 441 DPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 109 bits (261), Expect = 5e-24
Identities = 54/132 (40%), Positives = 84/132 (63%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + IKESLR++P VP + R T+D + G + KG ++++F H NP V+ P +
Sbjct: 381 LTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIICLISVFGTHHNPAVWPDPEVY 440
Query: 63 IPERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD +++ ++P +++ FSAGPRNCIGQ FAM EMKV L + F+++P EP
Sbjct: 441 DPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLGLTLLAFRVLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+L+LR++ G+
Sbjct: 501 KPELVLRAEGGL 512
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 107 bits (257), Expect = 1e-23
Identities = 54/132 (40%), Positives = 83/132 (62%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P P I R T+D + G + KG + +++I +H NP V+ P +
Sbjct: 381 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVY 440
Query: 63 IPERFDSLEHK--NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD K +P +++ FSAGPRNCIGQ FAM EMKV L+ ++ +F+ +P EP
Sbjct: 441 DPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+LI+R++ G+
Sbjct: 501 KLELIMRAEGGL 512
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 107 bits (257), Expect = 1e-23
Identities = 54/132 (40%), Positives = 83/132 (62%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P P I R T+D + G + KG + +++I +H NP V+ P +
Sbjct: 381 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVY 440
Query: 63 IPERFDSLEHK--NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD K +P +++ FSAGPRNCIGQ FAM EMKV L+ ++ +F+ +P EP
Sbjct: 441 DPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+LI+R++ G+
Sbjct: 501 KLELIMRAEGGL 512
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 107 bits (257), Expect = 1e-23
Identities = 54/132 (40%), Positives = 83/132 (62%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P P I R T+D + G + KG + +++I +H NP V+ P +
Sbjct: 381 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVY 440
Query: 63 IPERFDSLEHK--NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD K +P +++ FSAGPRNCIGQ FAM EMKV L+ ++ +F+ +P EP
Sbjct: 441 DPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+LI+R++ G+
Sbjct: 501 KLELIMRAEGGL 512
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 107 bits (257), Expect = 1e-23
Identities = 54/132 (40%), Positives = 83/132 (62%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P P I R T+D + G + KG + +++I +H NP V+ P +
Sbjct: 315 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVY 374
Query: 63 IPERFDSLEHK--NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD K +P +++ FSAGPRNCIGQ FAM EMKV L+ ++ +F+ +P EP
Sbjct: 375 DPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRR 434
Query: 121 CADLILRSQNGV 132
+LI+R++ G+
Sbjct: 435 KLELIMRAEGGL 446
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 107 bits (257), Expect = 1e-23
Identities = 54/132 (40%), Positives = 83/132 (62%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P P I R T+D + G + KG + +++I +H NP V+ P +
Sbjct: 381 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVY 440
Query: 63 IPERFDSLEHK--NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD K +P +++ FSAGPRNCIGQ FAM EMKV L+ ++ +F+ +P EP
Sbjct: 441 DPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+LI+R++ G+
Sbjct: 501 KLELIMRAEGGL 512
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 107 bits (257), Expect = 1e-23
Identities = 54/132 (40%), Positives = 83/132 (62%), Gaps = 3/132 (2%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEF 62
L + +KESLR++P P I R T+D + G + KG + +++I +H NP V+ P +
Sbjct: 381 LTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITCLIDIIGVHHNPTVWPDPEVY 440
Query: 63 IPERFDSLEHK--NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPIL 120
P RFD K +P +++ FSAGPRNCIGQ FAM EMKV L+ ++ +F+ +P EP
Sbjct: 441 DPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKVVLALMLLHFRFLPDHTEPRR 500
Query: 121 CADLILRSQNGV 132
+LI+R++ G+
Sbjct: 501 KLELIMRAEGGL 512
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 104 bits (250), Expect = 1e-22
Identities = 44/115 (38%), Positives = 76/115 (66%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+++ F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 104 bits (250), Expect = 1e-22
Identities = 44/115 (38%), Positives = 76/115 (66%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 352 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPE 411
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+++ F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 412 KFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 466
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 203 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 262
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 263 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 317
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 280 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 339
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 340 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 394
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 104 bits (249), Expect = 1e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGVVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 363 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 422
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 423 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 482
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 483 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 511
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 363 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 422
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 423 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 482
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 483 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 511
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 363 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 422
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 423 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 482
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 483 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 511
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 103 bits (248), Expect = 2e-22
Identities = 53/136 (38%), Positives = 88/136 (64%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+ R+ P+VP I R ++K G L G +VVL+I+ +H NP V++ P
Sbjct: 364 MSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 423
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ + ++P+++L FSAG RNCIGQ+FAM+E+KVT++ ++ +F++ P
Sbjct: 424 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 483
Query: 118 PILCAD-LILRSQNGV 132
P+ + IL+ +NG+
Sbjct: 484 PLTFPNHFILKPKNGM 499
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 364 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 423
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 424 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 483
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 484 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 512
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 103 bits (248), Expect = 2e-22
Identities = 53/136 (38%), Positives = 88/136 (64%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+ R+ P+VP I R ++K G L G +VVL+I+ +H NP V++ P
Sbjct: 364 MSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 423
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ + ++P+++L FSAG RNCIGQ+FAM+E+KVT++ ++ +F++ P
Sbjct: 424 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 483
Query: 118 PILCAD-LILRSQNGV 132
P+ + IL+ +NG+
Sbjct: 484 PLTFPNHFILKPKNGM 499
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 349 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 408
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 409 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 468
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 469 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 497
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 364 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 423
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 424 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 483
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 484 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 512
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 363 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 422
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 423 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 482
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 483 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 511
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 363 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 422
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 423 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 482
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 483 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 511
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 103 bits (248), Expect = 2e-22
Identities = 53/136 (38%), Positives = 88/136 (64%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+ R+ P+VP I R ++K G L G +VVL+I+ +H NP V++ P
Sbjct: 364 MSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 423
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ + ++P+++L FSAG RNCIGQ+FAM+E+KVT++ ++ +F++ P
Sbjct: 424 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 483
Query: 118 PILCAD-LILRSQNGV 132
P+ + IL+ +NG+
Sbjct: 484 PLTFPNHFILKPKNGM 499
>AL593856-7|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 349 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 408
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 409 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 468
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 469 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 497
>AL593856-6|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 364 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 423
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 424 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 483
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 484 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 512
>AL593856-5|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 363 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 422
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 423 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 482
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 483 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 511
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 103 bits (248), Expect = 2e-22
Identities = 53/136 (38%), Positives = 88/136 (64%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+ R+ P+VP I R ++K G L G +VVL+I+ +H NP V++ P
Sbjct: 364 MSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 423
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ + ++P+++L FSAG RNCIGQ+FAM+E+KVT++ ++ +F++ P
Sbjct: 424 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 483
Query: 118 PILCAD-LILRSQNGV 132
P+ + IL+ +NG+
Sbjct: 484 PLTFPNHFILKPKNGM 499
>AL356793-4|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 363 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 422
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 423 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 482
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 483 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 511
>AL356793-3|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 364 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 423
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 424 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 483
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 484 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 512
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 349 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 408
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 409 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 468
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 469 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 497
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 103 bits (248), Expect = 2e-22
Identities = 53/136 (38%), Positives = 88/136 (64%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+ R+ P+VP I R ++K G L G +VVL+I+ +H NP V++ P
Sbjct: 363 MSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 422
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ + ++P+++L FSAG RNCIGQ+FAM+E+KVT++ ++ +F++ P
Sbjct: 423 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 482
Query: 118 PILCAD-LILRSQNGV 132
P+ + IL+ +NG+
Sbjct: 483 PLTFPNHFILKPKNGM 498
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 103 bits (248), Expect = 2e-22
Identities = 53/136 (38%), Positives = 88/136 (64%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+ R+ P+VP I R ++K G L G +VVL+I+ +H NP V++ P
Sbjct: 364 MSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 423
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ + ++P+++L FSAG RNCIGQ+FAM+E+KVT++ ++ +F++ P
Sbjct: 424 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 483
Query: 118 PILCAD-LILRSQNGV 132
P+ + IL+ +NG+
Sbjct: 484 PLTFPNHFILKPKNGM 499
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 103 bits (248), Expect = 2e-22
Identities = 53/136 (38%), Positives = 88/136 (64%), Gaps = 4/136 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+ R+ P+VP I R ++K G L G +VVL+I+ +H NP V++ P
Sbjct: 299 MSYTTMCIKETCRLIPAVPSISRDLSKPLTFPDGCTLPAGITVVLSIWGLHHNPAVWKNP 358
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ + ++P+++L FSAG RNCIGQ+FAM+E+KVT++ ++ +F++ P
Sbjct: 359 KVFDPLRFSQENSDQRHPYAYLPFSAGSRNCIGQEFAMIELKVTIALILLHFRVTPDPTR 418
Query: 118 PILCAD-LILRSQNGV 132
P+ + IL+ +NG+
Sbjct: 419 PLTFPNHFILKPKNGM 434
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 103 bits (248), Expect = 2e-22
Identities = 62/150 (41%), Positives = 88/150 (58%), Gaps = 6/150 (4%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAE-VGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M L + IKES R+YP VP + R ++K V G L G+ + ++I+ +HRN V+ P
Sbjct: 363 MTYLTMCIKESFRLYPPVPQVYRQLSKPVTFVDGRSLPAGSLISMHIYALHRNSAVWPDP 422
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMK-VTLSTLVR-NFKLVPVD 115
F RF ++ ++PF+++ FSAGPRNCIGQ+FAM EMK VT L+R F L P
Sbjct: 423 EVFDSLRFSTENASKRHPFAFMPFSAGPRNCIGQQFAMSEMKVVTAMCLLRFEFSLDPSR 482
Query: 116 IEPILCADLILRSQNGVKVGFLPRTQSNSK 145
+ PI L+LRS+NG + P + K
Sbjct: 483 L-PIKMPQLVLRSKNGFHLHLKPLGPGSGK 511
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 103 bits (247), Expect = 2e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 467
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 103 bits (247), Expect = 2e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 354 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPE 413
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 414 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 468
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 103 bits (247), Expect = 2e-22
Identities = 44/115 (38%), Positives = 75/115 (65%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +HR+P+ + +P
Sbjct: 354 MEYLDMVVNETLRLFPIAMRLERVCKKDVEINGMFIPKGWVVMIPSYALHRDPKYWTEPE 413
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 414 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALMNMKLALIRVLQNFSFKP 468
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 101 bits (243), Expect = 7e-22
Identities = 44/114 (38%), Positives = 73/114 (64%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER KD E+ G+ + KG+ VV+ + +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHK-NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
EF PERF + +P+ + F GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 EFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKP 466
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 101 bits (243), Expect = 7e-22
Identities = 44/114 (38%), Positives = 73/114 (64%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER KD E+ G+ + KG+ VV+ + +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHK-NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
EF PERF + +P+ + F GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 EFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKP 466
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 101 bits (243), Expect = 7e-22
Identities = 44/114 (38%), Positives = 73/114 (64%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER KD E+ G+ + KG+ VV+ + +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVAIRLERTCMKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHK-NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
EF PERF + +P+ + F GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 EFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKP 466
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 101 bits (243), Expect = 7e-22
Identities = 44/114 (38%), Positives = 73/114 (64%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER KD E+ G+ + KG+ VV+ + +H +P+ + +P
Sbjct: 24 MEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPE 83
Query: 61 EFIPERFDSLEHK-NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
EF PERF + +P+ + F GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 84 EFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKP 137
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 101 bits (243), Expect = 7e-22
Identities = 44/114 (38%), Positives = 73/114 (64%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER KD E+ G+ + KG+ VV+ + +H +P+ + +P
Sbjct: 11 MEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPE 70
Query: 61 EFIPERFDSLEHK-NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
EF PERF + +P+ + F GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 71 EFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKP 124
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 101 bits (243), Expect = 7e-22
Identities = 44/114 (38%), Positives = 73/114 (64%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P +ER KD E+ G+ + KG+ VV+ + +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVAIRLERTCKKDVEINGVFIPKGSMVVIPTYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHK-NPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
EF PERF + +P+ + F GPRNCIG +FA+M MK+ L +++NF P
Sbjct: 413 EFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALMNMKLALIRVLQNFSFKP 466
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 99.5 bits (237), Expect = 4e-21
Identities = 56/134 (41%), Positives = 80/134 (59%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+ P
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM E+KV + + F+L+P P
Sbjct: 429 EVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIP 488
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 489 IPIARLVLKSKNGI 502
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 99.1 bits (236), Expect = 5e-21
Identities = 41/115 (35%), Positives = 74/115 (64%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +H +P+ + +P
Sbjct: 353 LEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA++ MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKP 467
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 99.1 bits (236), Expect = 5e-21
Identities = 41/115 (35%), Positives = 74/115 (64%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +H +P+ + +P
Sbjct: 353 LEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA++ MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKP 467
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 99.1 bits (236), Expect = 5e-21
Identities = 41/115 (35%), Positives = 74/115 (64%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +H +P+ + +P
Sbjct: 353 LEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA++ MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKP 467
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 99.1 bits (236), Expect = 5e-21
Identities = 41/115 (35%), Positives = 74/115 (64%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ L++V+ E+LR++P +ER+ KD E+ G+ + KG V++ + +H +P+ + +P
Sbjct: 353 LEYLDMVVNETLRLFPVAMRLERVCKKDVEINGMFIPKGVVVMIPSYVLHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKN--PFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F+PERF N P+ + F +GPRNCIG +FA++ MK+ L +++NF P
Sbjct: 413 KFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALVNMKLALVRVLQNFSFKP 467
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 98.3 bits (234), Expect = 9e-21
Identities = 56/134 (41%), Positives = 80/134 (59%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+ P
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM E+KV + + F+L+P P
Sbjct: 429 EVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIP 488
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 489 IPIARLVLKSKNGI 502
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 98.3 bits (234), Expect = 9e-21
Identities = 56/134 (41%), Positives = 80/134 (59%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+ P
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM E+KV + + F+L+P P
Sbjct: 429 EVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIP 488
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 489 IPIARLVLKSKNGI 502
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 98.3 bits (234), Expect = 9e-21
Identities = 56/134 (41%), Positives = 80/134 (59%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+ P
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM E+KV + + F+L+P P
Sbjct: 429 EVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIP 488
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 489 IPIARLVLKSKNGI 502
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 98.3 bits (234), Expect = 9e-21
Identities = 56/134 (41%), Positives = 80/134 (59%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+ P
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM E+KV + + F+L+P P
Sbjct: 429 EVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIP 488
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 489 IPIARLVLKSKNGI 502
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 97.9 bits (233), Expect = 1e-20
Identities = 55/134 (41%), Positives = 80/134 (59%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+ P
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM ++KV + + F+L+P P
Sbjct: 429 EVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIP 488
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 489 IPMARLVLKSKNGI 502
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 96.7 bits (230), Expect = 3e-20
Identities = 55/134 (41%), Positives = 80/134 (59%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+ P
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM ++KV + + F+L+P P
Sbjct: 429 EVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRTP 488
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 489 IPMARLVLKSKNGI 502
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 96.7 bits (230), Expect = 3e-20
Identities = 55/134 (41%), Positives = 80/134 (59%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR++P VP I R L T G L KG V+L+I+ +H NP+V+ P
Sbjct: 369 MPYTTMCIKEALRLFPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM E+KV + + F+L+P P
Sbjct: 429 EVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIP 488
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 489 IPIARLVLKSKNGI 502
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 95.5 bits (227), Expect = 6e-20
Identities = 60/136 (44%), Positives = 82/136 (60%), Gaps = 5/136 (3%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+ P
Sbjct: 370 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 429
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKV--TLSTLVRNFKLVPVDIE 117
F P RF ++ ++L FS G RNCIG++FAM E+KV TLVR F+L+P
Sbjct: 430 EVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVGQQALTLVR-FELLPDPTR 488
Query: 118 -PILCADLILRSQNGV 132
PI A L+L+S+NG+
Sbjct: 489 IPIPIARLVLKSKNGI 504
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 94.7 bits (225), Expect = 1e-19
Identities = 42/116 (36%), Positives = 77/116 (66%), Gaps = 4/116 (3%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P V + R+ KD E+ G+ + KG +V++ I+ +H +P+ + +P
Sbjct: 243 MEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPE 302
Query: 61 EFIPERFDSLEHKNP---FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F PERF S ++K+ + ++ F AGPRNCIG +FA+ +K+ + ++NF P
Sbjct: 303 KFCPERF-SKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 357
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 94.7 bits (225), Expect = 1e-19
Identities = 42/116 (36%), Positives = 77/116 (66%), Gaps = 4/116 (3%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P V + R+ KD E+ G+ + KG +V++ I+ +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKNP---FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F PERF S ++K+ + ++ F AGPRNCIG +FA+ +K+ + ++NF P
Sbjct: 413 KFCPERF-SKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 94.7 bits (225), Expect = 1e-19
Identities = 42/116 (36%), Positives = 77/116 (66%), Gaps = 4/116 (3%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P V + R+ KD E+ G+ + KG +V++ I+ +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKNP---FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F PERF S ++K+ + ++ F AGPRNCIG +FA+ +K+ + ++NF P
Sbjct: 413 KFCPERF-SKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 94.7 bits (225), Expect = 1e-19
Identities = 42/116 (36%), Positives = 77/116 (66%), Gaps = 4/116 (3%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P V + R+ KD E+ G+ + KG +V++ I+ +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKNP---FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F PERF S ++K+ + ++ F AGPRNCIG +FA+ +K+ + ++NF P
Sbjct: 413 KFCPERF-SKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 94.7 bits (225), Expect = 1e-19
Identities = 42/116 (36%), Positives = 77/116 (66%), Gaps = 4/116 (3%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P V + R+ KD E+ G+ + KG +V++ I+ +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKNP---FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F PERF S ++K+ + ++ F AGPRNCIG +FA+ +K+ + ++NF P
Sbjct: 413 KFCPERF-SKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 94.7 bits (225), Expect = 1e-19
Identities = 42/116 (36%), Positives = 77/116 (66%), Gaps = 4/116 (3%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P V + R+ KD E+ G+ + KG +V++ I+ +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKNP---FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F PERF S ++K+ + ++ F AGPRNCIG +FA+ +K+ + ++NF P
Sbjct: 413 KFCPERF-SKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 94.7 bits (225), Expect = 1e-19
Identities = 42/116 (36%), Positives = 77/116 (66%), Gaps = 4/116 (3%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P V + R+ KD E+ G+ + KG +V++ I+ +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKNP---FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F PERF S ++K+ + ++ F AGPRNCIG +FA+ +K+ + ++NF P
Sbjct: 413 KFCPERF-SKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 467
>AL135960-10|CAI19737.1| 519|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 519
Score = 93.9 bits (223), Expect = 2e-19
Identities = 54/134 (40%), Positives = 79/134 (58%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNL 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM ++KV + + F+L+P P
Sbjct: 429 EVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIP 488
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 489 IPMARLVLKSKNGI 502
>AL135960-9|CAI19736.1| 421|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 421
Score = 93.9 bits (223), Expect = 2e-19
Identities = 54/134 (40%), Positives = 79/134 (58%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+
Sbjct: 271 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNL 330
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM ++KV + + F+L+P P
Sbjct: 331 EVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIP 390
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 391 IPMARLVLKSKNGI 404
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 93.9 bits (223), Expect = 2e-19
Identities = 54/134 (40%), Positives = 79/134 (58%), Gaps = 2/134 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNL 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM ++KV + + F+L+P P
Sbjct: 429 EVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQLKVARALTLLRFELLPDPTRIP 488
Query: 119 ILCADLILRSQNGV 132
I A L+L+S+NG+
Sbjct: 489 IPIARLVLKSKNGI 502
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 93.5 bits (222), Expect = 3e-19
Identities = 54/131 (41%), Positives = 77/131 (58%), Gaps = 2/131 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG V+L+I+ +H NP+V+ P
Sbjct: 369 MPYTTMCIKEALRLYPPVPGIGRELSTPVTFPDGRSLPKGIMVLLSIYGLHHNPKVWPNP 428
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE-P 118
F P RF ++ ++L FS G RNCIG++FAM E+KV + + F+L+P P
Sbjct: 429 EVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNELKVATALTLLRFELLPDPTRIP 488
Query: 119 ILCADLILRSQ 129
I A L+L+S+
Sbjct: 489 IPIARLVLKSK 499
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 93.5 bits (222), Expect = 3e-19
Identities = 54/138 (39%), Positives = 79/138 (57%), Gaps = 4/138 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE LR+Y V I RL+ K G L G +V +NI+ +H NP +E P
Sbjct: 362 MPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDP 421
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ E +P++++ FSAG RNCIGQ FA++E KV ++ + FKL P
Sbjct: 422 QVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSR 481
Query: 118 PIL-CADLILRSQNGVKV 134
P ++L+S+NG+ V
Sbjct: 482 PPQPVRQVVLKSKNGIHV 499
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 93.5 bits (222), Expect = 3e-19
Identities = 54/138 (39%), Positives = 79/138 (57%), Gaps = 4/138 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE LR+Y V I RL+ K G L G +V +NI+ +H NP +E P
Sbjct: 362 MPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDP 421
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ E +P++++ FSAG RNCIGQ FA++E KV ++ + FKL P
Sbjct: 422 QVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSR 481
Query: 118 PIL-CADLILRSQNGVKV 134
P ++L+S+NG+ V
Sbjct: 482 PPQPVRQVVLKSKNGIHV 499
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 93.5 bits (222), Expect = 3e-19
Identities = 54/138 (39%), Positives = 79/138 (57%), Gaps = 4/138 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE LR+Y V I RL+ K G L G +V +NI+ +H NP +E P
Sbjct: 362 MPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDP 421
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ E +P++++ FSAG RNCIGQ FA++E KV ++ + FKL P
Sbjct: 422 QVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSR 481
Query: 118 PIL-CADLILRSQNGVKV 134
P ++L+S+NG+ V
Sbjct: 482 PPQPVRQVVLKSKNGIHV 499
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 93.5 bits (222), Expect = 3e-19
Identities = 54/138 (39%), Positives = 79/138 (57%), Gaps = 4/138 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE LR+Y V I RL+ K G L G +V +NI+ +H NP +E P
Sbjct: 362 MPYTTMCIKECLRLYAPVVNISRLLDKPITFPDGRSLPAGITVFINIWALHHNPYFWEDP 421
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIE 117
F P RF ++ E +P++++ FSAG RNCIGQ FA++E KV ++ + FKL P
Sbjct: 422 QVFNPLRFSRENSEKIHPYAFIPFSAGLRNCIGQHFAIIECKVAVALTLLRFKLAPDHSR 481
Query: 118 PIL-CADLILRSQNGVKV 134
P ++L+S+NG+ V
Sbjct: 482 PPQPVRQVVLKSKNGIHV 499
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 93.1 bits (221), Expect = 3e-19
Identities = 55/139 (39%), Positives = 85/139 (61%), Gaps = 6/139 (4%)
Query: 6 LVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIP 64
+ IKESLR YP V L+ R T+D ++ G + KG +++I+ H NP V+ + P
Sbjct: 390 MCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNP 449
Query: 65 ERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVDIEPILC 121
RFD + + ++P +++ FSAGPRNCIGQ FAM E++V ++ + F+L V +
Sbjct: 450 YRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRK 509
Query: 122 ADLILRSQNG--VKVGFLP 138
+LILR++NG +KV LP
Sbjct: 510 PELILRTENGLWLKVEPLP 528
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 93.1 bits (221), Expect = 3e-19
Identities = 55/139 (39%), Positives = 85/139 (61%), Gaps = 6/139 (4%)
Query: 6 LVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIP 64
+ IKESLR YP V L+ R T+D ++ G + KG +++I+ H NP V+ + P
Sbjct: 390 MCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNP 449
Query: 65 ERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVDIEPILC 121
RFD + + ++P +++ FSAGPRNCIGQ FAM E++V ++ + F+L V +
Sbjct: 450 YRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRK 509
Query: 122 ADLILRSQNG--VKVGFLP 138
+LILR++NG +KV LP
Sbjct: 510 PELILRTENGLWLKVEPLP 528
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 2,
subfamily E, polypeptide 2 homolog protein.
Length = 531
Score = 93.1 bits (221), Expect = 3e-19
Identities = 55/139 (39%), Positives = 85/139 (61%), Gaps = 6/139 (4%)
Query: 6 LVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIP 64
+ IKESLR YP V L+ R T+D ++ G + KG +++I+ H NP V+ + P
Sbjct: 390 MCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNP 449
Query: 65 ERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVDIEPILC 121
RFD + + ++P +++ FSAGPRNCIGQ FAM E++V ++ + F+L V +
Sbjct: 450 YRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRK 509
Query: 122 ADLILRSQNG--VKVGFLP 138
+LILR++NG +KV LP
Sbjct: 510 PELILRTENGLWLKVEPLP 528
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 93.1 bits (221), Expect = 3e-19
Identities = 55/139 (39%), Positives = 85/139 (61%), Gaps = 6/139 (4%)
Query: 6 LVIKESLRMYPSVPLIERLITKDAEV-GGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIP 64
+ IKESLR YP V L+ R T+D ++ G + KG +++I+ H NP V+ + P
Sbjct: 390 MCIKESLRQYPPVTLVSRQCTEDIKLPDGRIIPKGIICLVSIYGTHHNPTVWPDSKVYNP 449
Query: 65 ERFD--SLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVDIEPILC 121
RFD + + ++P +++ FSAGPRNCIGQ FAM E++V ++ + F+L V +
Sbjct: 450 YRFDPDNPQQRSPLAYVPFSAGPRNCIGQSFAMAELRVVVALTLLRFRLSVDRTRKVRRK 509
Query: 122 ADLILRSQNG--VKVGFLP 138
+LILR++NG +KV LP
Sbjct: 510 PELILRTENGLWLKVEPLP 528
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 91.9 bits (218), Expect = 8e-19
Identities = 40/116 (34%), Positives = 75/116 (64%), Gaps = 3/116 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P V + R+ KD E+ G+ + KG +V++ I+ +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKNP---FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F PE S ++K+ + ++ F AGPRNCIG +FA+ +K+ + ++NF P
Sbjct: 413 KFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 468
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 91.9 bits (218), Expect = 8e-19
Identities = 40/116 (34%), Positives = 75/116 (64%), Gaps = 3/116 (2%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M+ L++V+ E+LR++P V + R+ KD E+ G+ + KG +V++ I+ +H +P+ + +P
Sbjct: 353 MEYLDMVVNETLRLFPVVSRVTRVCKKDIEINGVFIPKGLAVMVPIYALHHDPKYWTEPE 412
Query: 61 EFIPERFDSLEHKNP---FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
+F PE S ++K+ + ++ F AGPRNCIG +FA+ +K+ + ++NF P
Sbjct: 413 KFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMRFALTNIKLAVIRALQNFSFKP 468
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 84.6 bits (200), Expect = 1e-16
Identities = 44/115 (38%), Positives = 70/115 (60%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ L V+KESLR+YP RL+ ++ + G+++ T ++ + + M R FE PL
Sbjct: 350 LQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPL 409
Query: 61 EFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVR--NFKLVP 113
F P+RF K F++ FS G R+CIGQ+FA ME+KV ++ L++ F+LVP
Sbjct: 410 TFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVP 464
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 84.6 bits (200), Expect = 1e-16
Identities = 44/115 (38%), Positives = 70/115 (60%), Gaps = 2/115 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ L V+KESLR+YP RL+ ++ + G+++ T ++ + + M R FE PL
Sbjct: 350 LQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGVRVPGNTPLLFSTYVMGRMDTYFEDPL 409
Query: 61 EFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVR--NFKLVP 113
F P+RF K F++ FS G R+CIGQ+FA ME+KV ++ L++ F+LVP
Sbjct: 410 TFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVP 464
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 84.2 bits (199), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPENFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 84.2 bits (199), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPKTFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 326 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 385
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 386 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 445
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 446 QLESKSALGPKNGVYIKIVSR 466
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAEDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 83.8 bits (198), Expect = 2e-16
Identities = 47/141 (33%), Positives = 79/141 (56%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 394 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 453
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G + ++E+K+TL ++ F+ P P+
Sbjct: 454 PERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLEVKLTLLHVLHKFRFQACPETQVPL 513
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 514 QLESKSALGPKNGVYIKIVSR 534
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 82.6 bits (195), Expect = 5e-16
Identities = 47/141 (33%), Positives = 78/141 (55%), Gaps = 5/141 (3%)
Query: 4 LELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFI 63
L++VI E+LRMYP R +D EV G ++ G + + + +H +PE + P F
Sbjct: 393 LDMVIAETLRMYPPAFRFTREAAQDCEVLGQRIPAGAVLEMAVGALHHDPEHWPSPETFN 452
Query: 64 PERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL--VPVDIEPI 119
PERF ++ + PF++L F AGPR+C+G ++E+K+TL ++ F+ P P+
Sbjct: 453 PERFTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLEVKLTLLHVLHKFRFQACPETQVPL 512
Query: 120 -LCADLILRSQNGVKVGFLPR 139
L + L +NGV + + R
Sbjct: 513 QLESKSALGPKNGVYIKIVSR 533
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 81.8 bits (193), Expect = 8e-16
Identities = 43/120 (35%), Positives = 67/120 (55%), Gaps = 1/120 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M L+ +KES+R+ PSVP R + K +G L KGT ++LN + + + FE
Sbjct: 117 MPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSS 176
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPI 119
+F PER+ E NPF+ L F G R CIG++ A +++ + L +VR + + D EP+
Sbjct: 177 QFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPV 236
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 81.8 bits (193), Expect = 8e-16
Identities = 43/120 (35%), Positives = 67/120 (55%), Gaps = 1/120 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M L+ +KES+R+ PSVP R + K +G L KGT ++LN + + + FE
Sbjct: 232 MPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSS 291
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPI 119
+F PER+ E NPF+ L F G R CIG++ A +++ + L +VR + + D EP+
Sbjct: 292 QFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPV 351
>AL138805-3|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 81.8 bits (193), Expect = 8e-16
Identities = 43/120 (35%), Positives = 67/120 (55%), Gaps = 1/120 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M L+ +KES+R+ PSVP R + K +G L KGT ++LN + + + FE
Sbjct: 374 MPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSS 433
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPI 119
+F PER+ E NPF+ L F G R CIG++ A +++ + L +VR + + D EP+
Sbjct: 434 QFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPV 493
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 81.8 bits (193), Expect = 8e-16
Identities = 43/120 (35%), Positives = 67/120 (55%), Gaps = 1/120 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M L+ +KES+R+ PSVP R + K +G L KGT ++LN + + + FE
Sbjct: 232 MPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSS 291
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPI 119
+F PER+ E NPF+ L F G R CIG++ A +++ + L +VR + + D EP+
Sbjct: 292 QFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPV 351
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 81.4 bits (192), Expect = 1e-15
Identities = 49/147 (33%), Positives = 80/147 (54%), Gaps = 8/147 (5%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M +L+ V+KE+LR+YP VP R+I K+ EV G K T V +++ R+P F +P
Sbjct: 383 MPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYEVSRDPTAFSEPE 442
Query: 61 EFIPERF------DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLV-- 112
F P R+ + ++PF + F G R C+G++ A +EM++ L+ L++ +K+V
Sbjct: 443 SFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLA 502
Query: 113 PVDIEPILCADLILRSQNGVKVGFLPR 139
P E A ++L V + FL R
Sbjct: 503 PETGELKSVARIVLVPNKKVGLQFLQR 529
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 80.2 bits (189), Expect = 3e-15
Identities = 42/120 (35%), Positives = 66/120 (55%), Gaps = 1/120 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M L+ +KES+R+ P VP R + K +G L KGT ++LN + + + FE
Sbjct: 373 MPYLKACLKESMRLTPGVPFTTRTLDKATVLGEYALPKGTVLMLNTQVLGSSEDNFEDSS 432
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEPI 119
+F PER+ E NPF+ L F G R CIG++ A +++ + L +VR + + D EP+
Sbjct: 433 QFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQLHLALCWIVRKYDIQATDNEPV 492
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 79.8 bits (188), Expect = 3e-15
Identities = 49/147 (33%), Positives = 79/147 (53%), Gaps = 8/147 (5%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M +L+ V+KE+LR+YP VP R+I K+ EV G K T V + + R+P F +P
Sbjct: 382 MPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPE 441
Query: 61 EFIPERF------DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLV-- 112
F P R+ + ++PF + F G R C+G++ A +EM++ L+ L++ +K+V
Sbjct: 442 SFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLA 501
Query: 113 PVDIEPILCADLILRSQNGVKVGFLPR 139
P E A ++L V + FL R
Sbjct: 502 PETGELKSVARIVLVPNKKVGLQFLQR 528
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 79.8 bits (188), Expect = 3e-15
Identities = 49/147 (33%), Positives = 79/147 (53%), Gaps = 8/147 (5%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M +L+ V+KE+LR+YP VP R+I K+ EV G K T V + + R+P F +P
Sbjct: 383 MPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPE 442
Query: 61 EFIPERF------DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLV-- 112
F P R+ + ++PF + F G R C+G++ A +EM++ L+ L++ +K+V
Sbjct: 443 SFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLA 502
Query: 113 PVDIEPILCADLILRSQNGVKVGFLPR 139
P E A ++L V + FL R
Sbjct: 503 PETGELKSVARIVLVPNKKVGLQFLQR 529
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 79.8 bits (188), Expect = 3e-15
Identities = 49/147 (33%), Positives = 79/147 (53%), Gaps = 8/147 (5%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M +L+ V+KE+LR+YP VP R+I K+ EV G K T V + + R+P F +P
Sbjct: 383 MPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPE 442
Query: 61 EFIPERF------DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLV-- 112
F P R+ + ++PF + F G R C+G++ A +EM++ L+ L++ +K+V
Sbjct: 443 SFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLA 502
Query: 113 PVDIEPILCADLILRSQNGVKVGFLPR 139
P E A ++L V + FL R
Sbjct: 503 PETGELKSVARIVLVPNKKVGLQFLQR 529
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 79.8 bits (188), Expect = 3e-15
Identities = 49/147 (33%), Positives = 79/147 (53%), Gaps = 8/147 (5%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
M +L+ V+KE+LR+YP VP R+I K+ EV G K T V + + R+P F +P
Sbjct: 383 MPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPE 442
Query: 61 EFIPERF------DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLV-- 112
F P R+ + ++PF + F G R C+G++ A +EM++ L+ L++ +K+V
Sbjct: 443 SFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLA 502
Query: 113 PVDIEPILCADLILRSQNGVKVGFLPR 139
P E A ++L V + FL R
Sbjct: 503 PETGELKSVARIVLVPNKKVGLQFLQR 529
>Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for
aromatase P-450. ).
Length = 503
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 353 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 411
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 412 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for
aromatase (estrogen synthetase). ).
Length = 503
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 353 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 411
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 412 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 78.2 bits (184), Expect = 1e-14
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Query: 3 VLELVIKESLRMYPSVP-LIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLE 61
+LE I+E LR+ P P LI D+ +G + KGT V++N++ +H N + + +P +
Sbjct: 352 LLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQ 411
Query: 62 FIPERF---DSLEHKNP-FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVD 115
F+PERF + +P S+L F AGPR+CIG+ A E+ + ++ L++ F L VP D
Sbjct: 412 FMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 78.2 bits (184), Expect = 1e-14
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Query: 3 VLELVIKESLRMYPSVP-LIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLE 61
+LE I+E LR+ P P LI D+ +G + KGT V++N++ +H N + + +P +
Sbjct: 352 LLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQ 411
Query: 62 FIPERF---DSLEHKNP-FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVD 115
F+PERF + +P S+L F AGPR+CIG+ A E+ + ++ L++ F L VP D
Sbjct: 412 FMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase
cytochrome P-450 gene, exon 10. ).
Length = 503
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 353 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 411
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 412 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatase
protein.
Length = 419
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 269 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 327
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 328 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 374
>M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase
mRNA, complete cds. ).
Length = 503
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 353 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 411
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 412 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 78.2 bits (184), Expect = 1e-14
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Query: 3 VLELVIKESLRMYPSVP-LIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLE 61
+LE I+E LR+ P P LI D+ +G + KGT V++N++ +H N + + +P +
Sbjct: 352 LLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQ 411
Query: 62 FIPERF---DSLEHKNP-FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVD 115
F+PERF + +P S+L F AGPR+CIG+ A E+ + ++ L++ F L VP D
Sbjct: 412 FMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase
(Aro1) mRNA, complete cds. ).
Length = 419
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 269 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 327
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 328 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 374
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 78.2 bits (184), Expect = 1e-14
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Query: 3 VLELVIKESLRMYPSVP-LIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLE 61
+LE I+E LR+ P P LI D+ +G + KGT V++N++ +H N + + +P +
Sbjct: 352 LLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQ 411
Query: 62 FIPERF---DSLEHKNP-FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVD 115
F+PERF + +P S+L F AGPR+CIG+ A E+ + ++ L++ F L VP D
Sbjct: 412 FMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein.
Length = 503
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 353 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 411
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 412 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 78.2 bits (184), Expect = 1e-14
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Query: 3 VLELVIKESLRMYPSVP-LIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLE 61
+LE I+E LR+ P P LI D+ +G + KGT V++N++ +H N + + +P +
Sbjct: 352 LLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQ 411
Query: 62 FIPERF---DSLEHKNP-FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVD 115
F+PERF + +P S+L F AGPR+CIG+ A E+ + ++ L++ F L VP D
Sbjct: 412 FMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfamily
19 subfamily A polypeptide 1 protein.
Length = 503
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 353 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 411
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 412 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 78.2 bits (184), Expect = 1e-14
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Query: 3 VLELVIKESLRMYPSVP-LIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLE 61
+LE I+E LR+ P P LI D+ +G + KGT V++N++ +H N + + +P +
Sbjct: 352 LLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQ 411
Query: 62 FIPERF---DSLEHKNP-FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVD 115
F+PERF + +P S+L F AGPR+CIG+ A E+ + ++ L++ F L VP D
Sbjct: 412 FMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 353 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 411
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 412 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 78.2 bits (184), Expect = 1e-14
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Query: 3 VLELVIKESLRMYPSVP-LIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLE 61
+LE I+E LR+ P P LI D+ +G + KGT V++N++ +H N + + +P +
Sbjct: 352 LLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQ 411
Query: 62 FIPERF---DSLEHKNP-FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVD 115
F+PERF + +P S+L F AGPR+CIG+ A E+ + ++ L++ F L VP D
Sbjct: 412 FMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 78.2 bits (184), Expect = 1e-14
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Query: 3 VLELVIKESLRMYPSVP-LIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLE 61
+LE I+E LR+ P P LI D+ +G + KGT V++N++ +H N + + +P +
Sbjct: 352 LLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQ 411
Query: 62 FIPERF---DSLEHKNP-FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVD 115
F+PERF + +P S+L F AGPR+CIG+ A E+ + ++ L++ F L VP D
Sbjct: 412 FMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 353 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 411
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 412 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family
19, subfamily A, polypeptide 1 protein.
Length = 503
Score = 78.2 bits (184), Expect = 1e-14
Identities = 48/111 (43%), Positives = 64/111 (57%), Gaps = 7/111 (6%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+KV+E I ES+R P V L+ R +D + G + KGT+++LNI +MHR E F KP
Sbjct: 353 LKVMENFIYESMRYQPVVDLVMRKALEDDVIDGYPVKKGTNIILNIGRMHR-LEFFPKPN 411
Query: 61 EFIPERFDSLEHKN-PFSWL-AFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
EF E F KN P+ + F GPR C G+ AM+ MK L TL+R F
Sbjct: 412 EFTLENF----AKNVPYRYFQPFGFGPRGCAGKYIAMVMMKAILVTLLRRF 458
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 78.2 bits (184), Expect = 1e-14
Identities = 44/119 (36%), Positives = 71/119 (59%), Gaps = 6/119 (5%)
Query: 3 VLELVIKESLRMYPSVP-LIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLE 61
+LE I+E LR+ P P LI D+ +G + KGT V++N++ +H N + + +P +
Sbjct: 352 LLEATIREVLRLRPVAPMLIPHKANVDSSIGEFAVDKGTEVIINLWALHHNEKEWHQPDQ 411
Query: 62 FIPERF---DSLEHKNP-FSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVD 115
F+PERF + +P S+L F AGPR+CIG+ A E+ + ++ L++ F L VP D
Sbjct: 412 FMPERFLNPAGTQLISPSVSYLPFGAGPRSCIGEILARQELFLIMAWLLQRFDLEVPDD 470
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 73.7 bits (173), Expect = 2e-13
Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+ +L+ V+KE LR+YP VP R+ KD VG + K T V L + R+P F +P
Sbjct: 367 LPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
F P R+ +PF+ L F G R+C+G++ A +E+++ L+ ++ +F++ P
Sbjct: 427 SFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQP 480
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 73.7 bits (173), Expect = 2e-13
Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+ +L+ V+KE LR+YP VP R+ KD VG + K T V L + R+P F +P
Sbjct: 367 LPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
F P R+ +PF+ L F G R+C+G++ A +E+++ L+ ++ +F++ P
Sbjct: 427 SFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQP 480
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 73.7 bits (173), Expect = 2e-13
Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+ +L+ V+KE LR+YP VP R+ KD VG + K T V L + R+P F +P
Sbjct: 367 LPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
F P R+ +PF+ L F G R+C+G++ A +E+++ L+ ++ +F++ P
Sbjct: 427 SFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQP 480
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 73.7 bits (173), Expect = 2e-13
Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+ +L+ V+KE LR+YP VP R+ KD VG + K T V L + R+P F +P
Sbjct: 367 LPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
F P R+ +PF+ L F G R+C+G++ A +E+++ L+ ++ +F++ P
Sbjct: 427 SFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQP 480
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 73.7 bits (173), Expect = 2e-13
Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+ +L+ V+KE LR+YP VP R+ KD VG + K T V L + R+P F +P
Sbjct: 367 LPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
F P R+ +PF+ L F G R+C+G++ A +E+++ L+ ++ +F++ P
Sbjct: 427 SFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQP 480
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 73.7 bits (173), Expect = 2e-13
Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+ +L+ V+KE LR+YP VP R+ KD VG + K T V L + R+P F +P
Sbjct: 367 LPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
F P R+ +PF+ L F G R+C+G++ A +E+++ L+ ++ +F++ P
Sbjct: 427 SFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQP 480
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 73.7 bits (173), Expect = 2e-13
Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+ +L+ V+KE LR+YP VP R+ KD VG + K T V L + R+P F +P
Sbjct: 367 LPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
F P R+ +PF+ L F G R+C+G++ A +E+++ L+ ++ +F++ P
Sbjct: 427 SFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQP 480
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 73.7 bits (173), Expect = 2e-13
Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+ +L+ V+KE LR+YP VP R+ KD VG + K T V L + R+P F +P
Sbjct: 367 LPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
F P R+ +PF+ L F G R+C+G++ A +E+++ L+ ++ +F++ P
Sbjct: 427 SFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQP 480
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 73.7 bits (173), Expect = 2e-13
Identities = 39/114 (34%), Positives = 66/114 (57%), Gaps = 1/114 (0%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+ +L+ V+KE LR+YP VP R+ KD VG + K T V L + R+P F +P
Sbjct: 367 LPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDYIIPKNTLVTLCHYATSRDPAQFPEPN 426
Query: 61 EFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
F P R+ +PF+ L F G R+C+G++ A +E+++ L+ ++ +F++ P
Sbjct: 427 SFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELELQMALAQILTHFEVQP 480
>AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 72.1 bits (169), Expect = 7e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHCTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 343 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 402
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 403 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 460
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 461 SLQPLPHCSVILKMQ 475
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 343 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 402
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 403 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 460
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 461 SLQPLPHCSVILKMQ 475
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 343 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 402
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 403 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 460
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 461 SLQPLPHCSVILKMQ 475
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>BX679671-8|CAM26071.1| 464|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 464
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 312 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 371
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 372 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 429
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 430 SLQPLPHCSVILKMQ 444
>BX679671-7|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 343 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 402
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 403 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 460
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 461 SLQPLPHCSVILKMQ 475
>AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGTHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 313 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 372
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 373 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 430
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 431 SLQPLPHCSVILKMQ 445
>AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 343 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 402
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 403 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 460
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 461 SLQPLPHCSVILKMQ 475
>AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 313 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 372
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 373 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 430
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 431 SLQPLPHCSVILKMQ 445
>AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 343 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 402
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 403 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 460
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 461 SLQPLPHCSVILKMQ 475
>AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 495
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 343 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 402
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 403 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 460
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 461 SLQPLPHCSVILKMQ 475
>AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 465
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 313 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 372
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 373 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 430
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 431 SLQPLPHCSVILKMQ 445
>AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P450,
subfamily XXIA (steroid 21-hydroxylase, congenital a
protein.
Length = 495
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 343 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 402
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 403 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 460
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 461 SLQPLPHCSVILKMQ 475
>AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens
cDNA FLJ30054 fis, clone ADRGL1000160, highly similar to
CYTOCHROME P450 XXIB (EC 1.14.99.10). ).
Length = 465
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 313 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 372
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 373 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 430
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 431 SLQPLPHCSVILKMQ 445
>AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 403
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 251 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 310
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 311 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 368
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 369 SLQPLPHCSVILKMQ 383
>AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450
21-hydroxylase protein.
Length = 495
Score = 71.7 bits (168), Expect = 9e-13
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 343 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 402
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 403 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 460
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 461 SLQPLPHCSVILKMQ 475
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 362 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 421
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 422 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 467
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 235 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 294
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 295 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 340
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 362 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 421
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 422 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 467
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 358 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 417
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 418 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 463
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 308 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 367
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 368 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 413
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 308 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 367
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 368 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 413
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 308 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 367
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 368 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 413
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 378 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 437
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 438 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 483
>AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,
CYP21 protein.
Length = 494
Score = 71.3 bits (167), Expect = 1e-12
Identities = 40/114 (35%), Positives = 64/114 (56%), Gaps = 3/114 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP 113
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLP 453
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/110 (35%), Positives = 63/110 (57%), Gaps = 2/110 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+K + VIKE+LR+ P VP R+ K E+ G ++ KG +V+ +I H E+F
Sbjct: 284 LKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKE 343
Query: 61 EFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRN 108
EF P+RF E + FS++ F G R+C+G++FA + +K+ L R+
Sbjct: 344 EFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 393
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/110 (35%), Positives = 63/110 (57%), Gaps = 2/110 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+K + VIKE+LR+ P VP R+ K E+ G ++ KG +V+ +I H E+F
Sbjct: 353 LKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKE 412
Query: 61 EFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRN 108
EF P+RF E + FS++ F G R+C+G++FA + +K+ L R+
Sbjct: 413 EFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 462
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/110 (35%), Positives = 63/110 (57%), Gaps = 2/110 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
+K + VIKE+LR+ P VP R+ K E+ G ++ KG +V+ +I H E+F
Sbjct: 353 LKYIGCVIKETLRLNPPVPGGFRVALKTFELNGYQIPKGWNVIYSICDTHDVAEIFTNKE 412
Query: 61 EFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRN 108
EF P+RF E + FS++ F G R+C+G++FA + +K+ L R+
Sbjct: 413 EFNPDRFMLPHPEDASRFSFIPFGGGLRSCVGKEFAKILLKIFTVELARH 462
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 71.3 bits (167), Expect = 1e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 428 VIHEVQRFGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 487
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 488 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 533
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 70.5 bits (165), Expect = 2e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 70.5 bits (165), Expect = 2e-12
Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
Query: 7 VIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPLEFIPE 65
VI E R VPL + + ++D EV G ++ KGT+++ N+ + ++ V+EKP F PE
Sbjct: 359 VIHEVQRFGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKPFRFHPE 418
Query: 66 RF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNF 109
F D+ H P ++L FSAG R C+G+ A ME+ + ++L+++F
Sbjct: 419 HFLDAQGHFVKPEAFLPFSAGRRACLGEPLARMELFLFFTSLLQHF 464
>M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein.
Length = 230
Score = 70.5 bits (165), Expect = 2e-12
Identities = 44/135 (32%), Positives = 73/135 (54%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 78 LPLLIATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 137
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+P
Sbjct: 138 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLLPSGDALP 195
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 196 SLQPLPHCSVILKMQ 210
>AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
Homo sapiens cholesterol 24-hydroxylase mRNA. ).
Length = 337
Score = 70.1 bits (164), Expect = 3e-12
Identities = 43/115 (37%), Positives = 64/115 (55%), Gaps = 12/115 (10%)
Query: 1 MKVLELVIKESLRMYPSVPLIERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKPL 60
++ L V+KESLR+YP RL+ ++ + G + + M R FE PL
Sbjct: 197 LQYLSQVLKESLRLYPPAWGTFRLLEEETLIDGF----------STYVMGRMDTYFEDPL 246
Query: 61 EFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVR--NFKLVP 113
F P+RF K F++ FS G R+CIGQ+FA ME+KV ++ L++ F+LVP
Sbjct: 247 TFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQMEVKVVMAKLLQRLEFRLVP 301
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 68.5 bits (160), Expect = 8e-12
Identities = 39/113 (34%), Positives = 63/113 (55%), Gaps = 3/113 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 343 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 402
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLV 112
EF P+RF LE LAF G R C+G+ A +E+ V L+ L++ F L+
Sbjct: 403 HEFWPDRF--LEPGKNSRALAFGCGARVCLGEPLARLELFVVLTRLLQAFTLL 453
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 67.7 bits (158), Expect = 1e-11
Identities = 37/89 (41%), Positives = 51/89 (57%), Gaps = 1/89 (1%)
Query: 1 MKVLELVIKESLRMYPSVPLIER-LITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + IKE+LR+YP VP I R L T G L KG +V+L+I+ +H NP+V+ P
Sbjct: 53 MPYTTMCIKEALRLYPPVPGISRELSTPVTFPDGRSLPKGITVMLSIYGLHHNPKVWPNP 112
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNC 88
F P RF ++ ++L FS G RNC
Sbjct: 113 EVFDPSRFAPGSAQHSHAFLPFSGGSRNC 141
>M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase
protein.
Length = 494
Score = 67.7 bits (158), Expect = 1e-11
Identities = 42/135 (31%), Positives = 72/135 (53%), Gaps = 8/135 (5%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
+ +L I E LR+ P VPL + T+ + + G + +GT ++ N+ H + V+E+P
Sbjct: 342 LPLLNATIAEVLRLRPVVPLALPHRTTRPSSISGYDIPEGTVIIPNLQGAHLDETVWERP 401
Query: 60 LEFIPERFDSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVP-----V 114
EF P+RF LE LAF G C+G+ A +++ V L+ L++ F L+P
Sbjct: 402 HEFWPDRF--LEPGKNSRALAFGCGAPVCLGEPLARLDLFVVLTRLLQAFTLLPSGDALP 459
Query: 115 DIEPILCADLILRSQ 129
++P+ +IL+ Q
Sbjct: 460 SLQPLPHCSVILKMQ 474
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 66.5 bits (155), Expect = 3e-11
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M VI E RM +PL + R +T D + G L KGT ++ N+ +HR+P + P
Sbjct: 359 MPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATP 418
Query: 60 LEFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEP 118
F P+ F ++ + K +++ FS G R C+G++ A E+ + ++L++ F P + E
Sbjct: 419 DTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEK 478
Query: 119 I 119
+
Sbjct: 479 L 479
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 66.5 bits (155), Expect = 3e-11
Identities = 44/124 (35%), Positives = 68/124 (54%), Gaps = 4/124 (3%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M E V+ E LR VPL I ++DA V G + KGT+V+ N++ +H + + + P
Sbjct: 358 MPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDP 417
Query: 60 LEFIPERF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVDI 116
F PERF DS + + + FS G R+C+G+ A MEM + + L++ F L P ++
Sbjct: 418 EVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHEL 477
Query: 117 EPIL 120
P L
Sbjct: 478 VPDL 481
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 66.5 bits (155), Expect = 3e-11
Identities = 44/124 (35%), Positives = 68/124 (54%), Gaps = 4/124 (3%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M E V+ E LR VPL I ++DA V G + KGT+V+ N++ +H + + + P
Sbjct: 358 MPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDP 417
Query: 60 LEFIPERF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVDI 116
F PERF DS + + + FS G R+C+G+ A MEM + + L++ F L P ++
Sbjct: 418 EVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHEL 477
Query: 117 EPIL 120
P L
Sbjct: 478 VPDL 481
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 66.5 bits (155), Expect = 3e-11
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M VI E RM +PL + R +T D + G L KGT ++ N+ +HR+P + P
Sbjct: 359 MPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATP 418
Query: 60 LEFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEP 118
F P+ F ++ + K +++ FS G R C+G++ A E+ + ++L++ F P + E
Sbjct: 419 DTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEK 478
Query: 119 I 119
+
Sbjct: 479 L 479
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 66.5 bits (155), Expect = 3e-11
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M VI E RM +PL + R +T D + G L KGT ++ N+ +HR+P + P
Sbjct: 359 MPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATP 418
Query: 60 LEFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEP 118
F P+ F ++ + K +++ FS G R C+G++ A E+ + ++L++ F P + E
Sbjct: 419 DTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEK 478
Query: 119 I 119
+
Sbjct: 479 L 479
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 66.5 bits (155), Expect = 3e-11
Identities = 44/124 (35%), Positives = 68/124 (54%), Gaps = 4/124 (3%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M E V+ E LR VPL I ++DA V G + KGT+V+ N++ +H + + + P
Sbjct: 358 MPYTEAVLHEVLRFCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDP 417
Query: 60 LEFIPERF-DSLEH-KNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVDI 116
F PERF DS + + + FS G R+C+G+ A MEM + + L++ F L P ++
Sbjct: 418 EVFHPERFLDSSGYFAKKEALVPFSLGRRHCLGEHLARMEMFLFFTALLQRFHLHFPHEL 477
Query: 117 EPIL 120
P L
Sbjct: 478 VPDL 481
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 66.5 bits (155), Expect = 3e-11
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M VI E RM +PL + R +T D + G L KGT ++ N+ +HR+P + P
Sbjct: 359 MPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATP 418
Query: 60 LEFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEP 118
F P+ F ++ + K +++ FS G R C+G++ A E+ + ++L++ F P + E
Sbjct: 419 DTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEK 478
Query: 119 I 119
+
Sbjct: 479 L 479
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 66.5 bits (155), Expect = 3e-11
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 2/121 (1%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M VI E RM +PL + R +T D + G L KGT ++ N+ +HR+P + P
Sbjct: 359 MPYTNAVIHEVQRMGNIIPLNVPREVTVDTTLAGYHLPKGTMILTNLTALHRDPTEWATP 418
Query: 60 LEFIPERF-DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPVDIEP 118
F P+ F ++ + K +++ FS G R C+G++ A E+ + ++L++ F P + E
Sbjct: 419 DTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTELFIFFTSLMQKFTFRPPNNEK 478
Query: 119 I 119
+
Sbjct: 479 L 479
>AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1
protein.
Length = 495
Score = 65.7 bits (153), Expect = 6e-11
Identities = 37/117 (31%), Positives = 62/117 (52%), Gaps = 3/117 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M + VI E R +P+ + +T+D G + KGT V+ + +H +P F P
Sbjct: 350 MPYTDAVIHEVQRFADIIPMNLPHRVTRDTAFRGFLIPKGTDVITLLNTVHYDPSQFLTP 409
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKLVPV 114
EF PE F + K +++ FSAG R C+G+ A ME+ + L+ ++++F L P+
Sbjct: 410 QEFNPEHFLDANQSFKKSPAFMPFSAGRRLCLGESLARMELFLYLTAILQSFSLQPL 466
>X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mRNA
for P-450 IIA4 protein. ).
Length = 494
Score = 65.3 bits (152), Expect = 8e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M +E VI E R +P+ + R + KD + L KGT V + + R+P F P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL 111
+F P+ F + + K +++ FS G RNC G+ A ME+ + +T+++NF+L
Sbjct: 409 QDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRL 462
>X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is 3rd
base in codon) protein.
Length = 448
Score = 65.3 bits (152), Expect = 8e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M +E VI E R +P+ + R + KD + L KGT V + + R+P F P
Sbjct: 303 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 362
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL 111
+F P+ F + + K +++ FS G RNC G+ A ME+ + +T+++NF+L
Sbjct: 363 QDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRL 416
>X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for
cytochrome P-450IIA. ).
Length = 489
Score = 65.3 bits (152), Expect = 8e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M +E VI E R +P+ + R + KD + L KGT V + + R+P F P
Sbjct: 344 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 403
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL 111
+F P+ F + + K +++ FS G RNC G+ A ME+ + +T+++NF+L
Sbjct: 404 QDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRL 457
>M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein.
Length = 494
Score = 65.3 bits (152), Expect = 8e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M +E VI E R +P+ + R + KD + L KGT V + + R+P F P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL 111
+F P+ F + + K +++ FS G RNC G+ A ME+ + +T+++NF+L
Sbjct: 409 QDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRL 462
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 65.3 bits (152), Expect = 8e-11
Identities = 39/125 (31%), Positives = 71/125 (56%), Gaps = 5/125 (4%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M E I E R+ VPL I + +++ + G + KGT ++ N++ +HR+P ++EKP
Sbjct: 400 MPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKP 459
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVDI 116
+F P RF D + +++ F G R C+G++ A ME+ + +L+++F +P D
Sbjct: 460 EDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDS 519
Query: 117 -EPIL 120
+P+L
Sbjct: 520 KKPLL 524
>BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 65.3 bits (152), Expect = 8e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M +E VI E R +P+ + R + KD + L KGT V + + R+P F P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL 111
+F P+ F + + K +++ FS G RNC G+ A ME+ + +T+++NF+L
Sbjct: 409 QDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRL 462
>BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 65.3 bits (152), Expect = 8e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M +E VI E R +P+ + R + KD + L KGT V + + R+P F P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL 111
+F P+ F + + K +++ FS G RNC G+ A ME+ + +T+++NF+L
Sbjct: 409 QDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRL 462
>BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 65.3 bits (152), Expect = 8e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M +E VI E R +P+ + R + KD + L KGT V + + R+P F P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL 111
+F P+ F + + K +++ FS G RNC G+ A ME+ + +T+++NF+L
Sbjct: 409 QDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRL 462
>BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family 2,
subfamily A, polypeptide 6 protein.
Length = 494
Score = 65.3 bits (152), Expect = 8e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M +E VI E R +P+ + R + KD + L KGT V + + R+P F P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL 111
+F P+ F + + K +++ FS G RNC G+ A ME+ + +T+++NF+L
Sbjct: 409 QDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRL 462
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 65.3 bits (152), Expect = 8e-11
Identities = 39/125 (31%), Positives = 71/125 (56%), Gaps = 5/125 (4%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M E I E R+ VPL I + +++ + G + KGT ++ N++ +HR+P ++EKP
Sbjct: 400 MPYTEATIMEVQRLTVVVPLAIPHMTSENTVLQGYTIPKGTLILPNLWSVHRDPAIWEKP 459
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL-VPVDI 116
+F P RF D + +++ F G R C+G++ A ME+ + +L+++F +P D
Sbjct: 460 EDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKMELFLMFVSLMQSFAFALPEDS 519
Query: 117 -EPIL 120
+P+L
Sbjct: 520 KKPLL 524
>AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6
protein.
Length = 494
Score = 65.3 bits (152), Expect = 8e-11
Identities = 37/114 (32%), Positives = 61/114 (53%), Gaps = 3/114 (2%)
Query: 1 MKVLELVIKESLRMYPSVPL-IERLITKDAEVGGLKLSKGTSVVLNIFQMHRNPEVFEKP 59
M +E VI E R +P+ + R + KD + L KGT V + + R+P F P
Sbjct: 349 MPYMEAVIHEIQRFGDVIPMSLARRVKKDTKFRDFFLPKGTEVYPMLGSVLRDPSFFSNP 408
Query: 60 LEFIPERF--DSLEHKNPFSWLAFSAGPRNCIGQKFAMMEMKVTLSTLVRNFKL 111
+F P+ F + + K +++ FS G RNC G+ A ME+ + +T+++NF+L
Sbjct: 409 QDFNPQHFLNEKGQFKKSDAFVPFSIGKRNCFGEGLARMELFLFFTTVMQNFRL 462
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.322 0.138 0.399
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 20,046,597
Number of Sequences: 224733
Number of extensions: 696416
Number of successful extensions: 1821
Number of sequences better than 10.0: 423
Number of HSP's better than 10.0 without gapping: 396
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 1008
Number of HSP's gapped (non-prelim): 427
length of query: 146
length of database: 73,234,838
effective HSP length: 83
effective length of query: 63
effective length of database: 54,581,999
effective search space: 3438665937
effective search space used: 3438665937
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.9 bits)
S2: 61 (28.7 bits)
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