Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000866-TA|BGIBMGA000866-PA|IPR000246|Peptidase T2,
asparaginase 2
(248 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q16VX6 Cluster: N(4)-(Beta-n-acetylglucosaminyl)-l-aspa... 273 2e-72
UniRef50_Q8MR45 Cluster: GH25655p; n=6; Endopterygota|Rep: GH256... 264 1e-69
UniRef50_P20933 Cluster: N(4)-(beta-N-acetylglucosaminyl)-L-aspa... 241 2e-62
UniRef50_UPI000155C291 Cluster: PREDICTED: similar to lysosomal ... 225 8e-58
UniRef50_Q21697 Cluster: Putative N(4)-(beta-N-acetylglucosaminy... 224 2e-57
UniRef50_Q5DGG1 Cluster: SJCHGC09117 protein; n=1; Schistosoma j... 210 2e-53
UniRef50_UPI000023DB25 Cluster: hypothetical protein FG02189.1; ... 209 4e-53
UniRef50_Q9W2C3 Cluster: CG4372-PA; n=2; Sophophora|Rep: CG4372-... 194 1e-48
UniRef50_Q56W64 Cluster: Probable L-asparaginase 3 precursor (EC... 188 2e-46
UniRef50_UPI0000E484F2 Cluster: PREDICTED: similar to LOC496249 ... 181 1e-44
UniRef50_A6C783 Cluster: Asparaginase; n=1; Planctomyces maris D... 123 4e-27
UniRef50_Q47898 Cluster: N(4)-(Beta-N-acetylglucosaminyl)-L-aspa... 121 1e-26
UniRef50_Q2GPW6 Cluster: Putative uncharacterized protein; n=2; ... 121 2e-26
UniRef50_A2TS29 Cluster: Asparaginase; n=9; Bacteroidetes|Rep: A... 120 5e-26
UniRef50_Q7S2Q8 Cluster: Putative uncharacterized protein NCU097... 116 4e-25
UniRef50_Q02BR8 Cluster: Peptidase T2, asparaginase 2; n=1; Soli... 110 3e-23
UniRef50_A4A1V3 Cluster: Asparaginase; n=1; Blastopirellula mari... 107 3e-22
UniRef50_Q15ZN1 Cluster: Twin-arginine translocation pathway sig... 104 2e-21
UniRef50_A1RYG2 Cluster: Peptidase T2, asparaginase 2; n=1; Ther... 99 1e-19
UniRef50_Q1IU43 Cluster: Peptidase T2, asparaginase 2 precursor;... 98 2e-19
UniRef50_Q2RZ81 Cluster: Asparaginase; n=1; Salinibacter ruber D... 95 1e-18
UniRef50_Q08CE9 Cluster: Zgc:153169; n=5; Danio rerio|Rep: Zgc:1... 94 3e-18
UniRef50_A0X701 Cluster: Peptidase T2, asparaginase 2 precursor;... 91 2e-17
UniRef50_A3HZD4 Cluster: Asparaginase; n=1; Algoriphagus sp. PR1... 89 1e-16
UniRef50_A6D1A2 Cluster: Asparaginase; n=1; Vibrio shilonii AK1|... 87 5e-16
UniRef50_A7T1K5 Cluster: Predicted protein; n=2; Nematostella ve... 83 5e-15
UniRef50_Q1IU95 Cluster: Peptidase T2, asparaginase 2; n=3; Bact... 83 8e-15
UniRef50_A1VC55 Cluster: Peptidase T2, asparaginase 2; n=4; Bact... 83 8e-15
UniRef50_A5UPJ1 Cluster: Asparaginase; n=2; Roseiflexus|Rep: Asp... 82 1e-14
UniRef50_Q8U4E6 Cluster: Putative L-asparaginase; n=4; Thermococ... 82 1e-14
UniRef50_A4WD66 Cluster: Peptidase T2, asparaginase 2; n=10; Bac... 81 2e-14
UniRef50_A3UJ27 Cluster: Asparaginase; n=1; Oceanicaulis alexand... 79 8e-14
UniRef50_A3H9E5 Cluster: Peptidase T2, asparaginase 2; n=1; Cald... 79 1e-13
UniRef50_A5URB1 Cluster: Asparaginase; n=2; Roseiflexus|Rep: Asp... 78 2e-13
UniRef50_Q0LJI7 Cluster: Peptidase T2, asparaginase 2; n=1; Herp... 76 7e-13
UniRef50_A5D1N1 Cluster: Asparaginase; n=1; Pelotomaculum thermo... 75 1e-12
UniRef50_A2E938 Cluster: Family T2, asparaginase-like threonine ... 75 1e-12
UniRef50_Q8ZTV2 Cluster: Asparaginase; n=4; Pyrobaculum|Rep: Asp... 74 4e-12
UniRef50_UPI0000ECCAEA Cluster: asparaginase-like 1 protein; n=6... 73 9e-12
UniRef50_A7HAG4 Cluster: Asparaginase; n=2; Anaeromyxobacter|Rep... 73 9e-12
UniRef50_P30364 Cluster: L-asparaginase precursor (EC 3.5.1.1) (... 72 2e-11
UniRef50_Q4JBL1 Cluster: Asparaginase; n=4; Sulfolobaceae|Rep: A... 71 3e-11
UniRef50_A0IK19 Cluster: Peptidase T2, asparaginase 2; n=7; Prot... 71 4e-11
UniRef50_Q54WW4 Cluster: Putative asparaginase 2; n=1; Dictyoste... 70 5e-11
UniRef50_Q7UGC2 Cluster: L-asparaginase; n=1; Pirellula sp.|Rep:... 69 1e-10
UniRef50_Q4HJQ2 Cluster: Asparaginase family protein; n=5; Campy... 68 2e-10
UniRef50_Q0HJ56 Cluster: Peptidase T2, asparaginase 2 precursor;... 68 3e-10
UniRef50_A0PCJ8 Cluster: Putative asparaginase; n=1; Streptomyce... 68 3e-10
UniRef50_Q8CWF3 Cluster: L-asparaginase; n=3; Bifidobacterium|Re... 67 3e-10
UniRef50_Q47V06 Cluster: Asparaginase; n=2; Gammaproteobacteria|... 66 6e-10
UniRef50_Q3SHK2 Cluster: Putative asparaginase; n=1; Thiobacillu... 65 1e-09
UniRef50_Q2S311 Cluster: Asparaginase superfamily; n=1; Saliniba... 65 1e-09
UniRef50_Q2RYX8 Cluster: Asparaginase; n=3; Bacteria|Rep: Aspara... 65 2e-09
UniRef50_Q9VXT7 Cluster: Probable L-asparaginase CG7860; n=3; Di... 65 2e-09
UniRef50_Q4RQ97 Cluster: Chromosome 17 SCAF15006, whole genome s... 62 1e-08
UniRef50_Q16RJ1 Cluster: L-asparaginase; n=5; Endopterygota|Rep:... 62 1e-08
UniRef50_A2BJV5 Cluster: L asparaginase; n=1; Hyperthermus butyl... 62 1e-08
UniRef50_Q62CC7 Cluster: Asparaginase family protein; n=30; cell... 62 1e-08
UniRef50_Q1VJC1 Cluster: Probable l-asparaginase protein; n=1; P... 62 1e-08
UniRef50_A3DPP6 Cluster: Peptidase T2, asparaginase 2; n=1; Stap... 62 1e-08
UniRef50_A7RM62 Cluster: Predicted protein; n=3; Nematostella ve... 62 2e-08
UniRef50_A6BYT5 Cluster: Putative asparaginase; n=1; Planctomyce... 61 2e-08
UniRef50_A7SD31 Cluster: Predicted protein; n=1; Nematostella ve... 61 3e-08
UniRef50_Q9AAM1 Cluster: Asparaginase family protein; n=6; Alpha... 60 5e-08
UniRef50_A0VHR1 Cluster: Peptidase T2, asparaginase 2; n=6; Prot... 60 7e-08
UniRef50_A7SKS4 Cluster: Predicted protein; n=1; Nematostella ve... 60 7e-08
UniRef50_P50287 Cluster: L-asparaginase 1 precursor (EC 3.5.1.1)... 58 2e-07
UniRef50_A0RU73 Cluster: L-asparaginase; n=2; Cenarchaeum symbio... 58 3e-07
UniRef50_UPI000155F543 Cluster: PREDICTED: similar to ASRGL1 pro... 57 5e-07
UniRef50_A4BV37 Cluster: Putative L-asparaginase; n=1; Nitrococc... 57 5e-07
UniRef50_Q7L266 Cluster: L-asparaginase; n=17; Euteleostomi|Rep:... 57 5e-07
UniRef50_A6WWK5 Cluster: Peptidase T2 asparaginase 2; n=1; Ochro... 56 6e-07
UniRef50_A5BIQ7 Cluster: Putative uncharacterized protein; n=2; ... 56 6e-07
UniRef50_Q6L1Z2 Cluster: Asparaginase; n=4; Thermoplasmatales|Re... 56 6e-07
UniRef50_A7D1A3 Cluster: Asparaginase; n=1; Halorubrum lacusprof... 56 6e-07
UniRef50_UPI0000DB78D0 Cluster: PREDICTED: similar to asparagina... 56 8e-07
UniRef50_A3WE63 Cluster: Asparaginase family protein; n=3; Eryth... 56 8e-07
UniRef50_A3EVA9 Cluster: Asparaginase; n=1; Leptospirillum sp. G... 55 2e-06
UniRef50_Q6A5Z2 Cluster: Putative asparaginase; n=1; Propionibac... 54 3e-06
UniRef50_Q7CRG0 Cluster: AGR_L_3520p; n=2; Agrobacterium tumefac... 54 4e-06
UniRef50_Q9H6P5 Cluster: Threonine aspartase 1 (EC 3.4.25.-) (Ta... 54 4e-06
UniRef50_A1ZI34 Cluster: Asparaginase; n=1; Microscilla marina A... 53 8e-06
UniRef50_Q0E667 Cluster: L-asparaginase; n=3; Spermatophyta|Rep:... 53 8e-06
UniRef50_Q1E8D8 Cluster: Putative uncharacterized protein; n=1; ... 53 8e-06
UniRef50_UPI000038C5E9 Cluster: COG1446: Asparaginase; n=1; Nost... 52 1e-05
UniRef50_Q1GP93 Cluster: Peptidase T2, asparaginase 2 precursor;... 52 1e-05
UniRef50_Q4SA00 Cluster: Chromosome undetermined SCAF14693, whol... 52 2e-05
UniRef50_Q4P5A6 Cluster: Putative uncharacterized protein; n=1; ... 52 2e-05
UniRef50_A6LCT8 Cluster: Asparaginase family protein; n=2; Bacte... 51 2e-05
UniRef50_UPI0000E45F91 Cluster: PREDICTED: similar to Tasp1 prot... 51 3e-05
UniRef50_A1CEN4 Cluster: Asparaginase, putative; n=4; Trichocoma... 51 3e-05
UniRef50_A6G504 Cluster: Peptidase T2, asparaginase 2; n=1; Ples... 50 5e-05
UniRef50_UPI000051A5AD Cluster: PREDICTED: similar to Threonine ... 50 7e-05
UniRef50_Q3UJT0 Cluster: TIB-55 BB88 cDNA, RIKEN full-length enr... 50 7e-05
UniRef50_Q0U541 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_Q0TZH7 Cluster: Putative uncharacterized protein; n=1; ... 49 1e-04
UniRef50_UPI0000E4D55A Cluster: UPI0000E4D55A related cluster; n... 48 2e-04
UniRef50_A4KSC8 Cluster: Asparaginase; n=10; Francisella tularen... 48 2e-04
UniRef50_A6RA67 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q9P6N7 Cluster: L-asparaginase; n=1; Schizosaccharomyce... 48 2e-04
UniRef50_Q2ULY7 Cluster: Asparaginase; n=2; Aspergillus|Rep: Asp... 48 2e-04
UniRef50_A2RAH7 Cluster: Catalytic activity:; n=3; Aspergillus|R... 48 2e-04
UniRef50_Q5UXA3 Cluster: Asparaginase family protein; n=4; Halob... 48 2e-04
UniRef50_Q2GRS5 Cluster: Putative uncharacterized protein; n=1; ... 47 5e-04
UniRef50_Q9VUX9 Cluster: CG5241-PA; n=4; Diptera|Rep: CG5241-PA ... 46 7e-04
UniRef50_Q7S5Y2 Cluster: Putative uncharacterized protein NCU056... 46 7e-04
UniRef50_UPI0000D57224 Cluster: PREDICTED: similar to CG5241-PA;... 46 9e-04
UniRef50_A1CBA9 Cluster: Asparaginase family protein; n=4; Trich... 46 9e-04
UniRef50_UPI00015B4DAB Cluster: PREDICTED: similar to taspase, t... 45 0.002
UniRef50_Q54RC1 Cluster: Putative asparaginase 2; n=1; Dictyoste... 45 0.002
UniRef50_P74383 Cluster: Putative L-asparaginase; n=11; Cyanobac... 45 0.002
UniRef50_A3J5D1 Cluster: Asparaginase; n=3; Bacteroidetes|Rep: A... 44 0.003
UniRef50_A6QTZ1 Cluster: Predicted protein; n=2; Onygenales|Rep:... 44 0.004
UniRef50_O65268 Cluster: Putative L-asparaginase 4 precursor (EC... 44 0.004
UniRef50_UPI000023D475 Cluster: hypothetical protein FG10857.1; ... 44 0.005
UniRef50_A5V870 Cluster: Peptidase T2, asparaginase 2 precursor;... 44 0.005
UniRef50_Q5DEJ8 Cluster: SJCHGC02349 protein; n=1; Schistosoma j... 44 0.005
UniRef50_UPI0000D56B77 Cluster: PREDICTED: similar to asparagina... 43 0.006
UniRef50_A2XLP6 Cluster: Putative uncharacterized protein; n=2; ... 43 0.006
UniRef50_A7E9Y4 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_Q9P6D1 Cluster: Related to asparaginase; n=2; Sordarial... 42 0.019
UniRef50_A6S1U0 Cluster: Putative uncharacterized protein; n=2; ... 42 0.019
UniRef50_A4R4C7 Cluster: Putative uncharacterized protein; n=1; ... 42 0.019
UniRef50_Q7NPM0 Cluster: L-asparaginase; n=1; Gloeobacter violac... 40 0.044
UniRef50_Q01KK7 Cluster: OSIGBa0118P15.4 protein; n=17; Oryza sa... 36 0.72
UniRef50_Q9XTB8 Cluster: Putative uncharacterized protein; n=2; ... 36 1.3
UniRef50_A5E466 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_Q82KS4 Cluster: Putative fatty acid desaturase; n=1; St... 35 2.2
UniRef50_A3AK54 Cluster: Putative uncharacterized protein; n=1; ... 35 2.2
UniRef50_A7HXC8 Cluster: Alpha amylase catalytic region; n=1; Pa... 34 2.9
UniRef50_P11110 Cluster: Neck protein Gp13; n=11; Viruses|Rep: N... 33 5.1
UniRef50_A7AQA6 Cluster: Membrane protein, putative; n=1; Babesi... 33 6.7
UniRef50_A0DQ79 Cluster: Chromosome undetermined scaffold_6, who... 33 6.7
UniRef50_Q259G2 Cluster: H0124B04.14 protein; n=3; Oryza sativa|... 33 8.9
UniRef50_P83451 Cluster: N(4)-(beta-N-acetylglucosaminyl)-L-aspa... 33 8.9
>UniRef50_Q16VX6 Cluster:
N(4)-(Beta-n-acetylglucosaminyl)-l-asparaginase; n=3;
Endopterygota|Rep:
N(4)-(Beta-n-acetylglucosaminyl)-l-asparaginase - Aedes
aegypti (Yellowfever mosquito)
Length = 380
Score = 273 bits (670), Expect = 2e-72
Identities = 131/262 (50%), Positives = 168/262 (64%), Gaps = 16/262 (6%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
MN+GAV LR IKHAI+VA+HVL++TKH+ LVG AT FAV MGFQ E+L T S+++W
Sbjct: 115 MNVGAVAALREIKHAIAVAKHVLENTKHTMLVGRQATDFAVMMGFQRETLQTDYSREMWE 174
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQ-------------KHEYSHHLLKKSHLNVDRF 107
+W +HCQPNFW NV P P+ +CGPY+ + + + L+ R+
Sbjct: 175 QWKT-NHCQPNFWTNVIPSPSMSCGPYEPISGNSINENYLPEADDAAQKLEPVEPEFGRY 233
Query: 108 NHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXV 167
NHDTIGM+ ID +G + AGTSTNGA+ KIPGR+GDSPI GSGAY +
Sbjct: 234 NHDTIGMIVIDANGHVVAGTSTNGARNKIPGRVGDSPIVGSGAYADSTVGAAAATGDGDI 293
Query: 168 MLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINM 227
M+RF+PS L VE +R+G SP A + A+ARIA HYPDF+G +V DGEYGAACHG+
Sbjct: 294 MMRFMPSLLAVEGLRQGLSPMLAGEAALARIAKHYPDFVGGIVVATKDGEYGAACHGLTQ 353
Query: 228 FPYVVYDKKHSSYQIV--NVSC 247
FPY V Q+V V+C
Sbjct: 354 FPYSVAQGTEPEAQVVVKTVNC 375
>UniRef50_Q8MR45 Cluster: GH25655p; n=6; Endopterygota|Rep: GH25655p
- Drosophila melanogaster (Fruit fly)
Length = 393
Score = 264 bits (647), Expect = 1e-69
Identities = 125/236 (52%), Positives = 160/236 (67%), Gaps = 5/236 (2%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
M++GAV GLRRIK AI VARHVL+HT+H+ LVG+ A+ FA MGF+ ESL T SK +W+
Sbjct: 130 MDVGAVAGLRRIKDAIKVARHVLEHTQHTMLVGDAASAFANAMGFESESLVTPESKDMWL 189
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLK----KSHLNVDRFNHDTIGMVA 116
+W E+ CQPNFW NV PDP +CGPY+ K ++ + R NHDTIGM+A
Sbjct: 190 QWTAEN-CQPNFWKNVHPDPKVSCGPYKPRPTPLTRWKEDRARNEYEIGRKNHDTIGMIA 248
Query: 117 IDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFL 176
ID +I AGTSTNGA++KIPGR+GDSPIPG+GAY VM+RFLPS L
Sbjct: 249 IDVESNIHAGTSTNGARHKIPGRVGDSPIPGAGAYADNEVGAAVATGDGDVMMRFLPSLL 308
Query: 177 TVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINMFPYVV 232
VE MR G P +AA+ + RI H+ DFMGA++A+ G YGAAC+G+ FP++V
Sbjct: 309 AVETMRAGKPPAEAAQEGLRRILKHHKDFMGALIAVDRLGNYGAACYGLAEFPFMV 364
>UniRef50_P20933 Cluster:
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
precursor (EC 3.5.1.26) (Glycosylasparaginase)
(Aspartylglucosaminidase) (N4-(N-
acetyl-beta-glucosaminyl)-L-asparagine amidase) (AGA)
[Contains: Glycosylasparaginase alpha chain;
Glycosylasparaginase beta chain]; n=33; Eumetazoa|Rep:
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
precursor (EC 3.5.1.26) (Glycosylasparaginase)
(Aspartylglucosaminidase) (N4-(N-
acetyl-beta-glucosaminyl)-L-asparagine amidase) (AGA)
[Contains: Glycosylasparaginase alpha chain;
Glycosylasparaginase beta chain] - Homo sapiens (Human)
Length = 346
Score = 241 bits (589), Expect = 2e-62
Identities = 119/250 (47%), Positives = 154/250 (61%), Gaps = 4/250 (1%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
M++GAVG LRRIK+AI VAR VL+HT H+ LVGE AT FA MGF E L+TS S+ L
Sbjct: 97 MDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTSASQALHS 156
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
W +CQPN+W NV PDP++ CGPY+ + D HDTIGMV I +
Sbjct: 157 DWL-ARNCQPNYWRNVIPDPSKYCGPYKPPGILKQDIPIHKETEDDRGHDTIGMVVIHKT 215
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
G IAAGTSTNG K+KI GR+GDSPIPG+GAY +++RFLPS+ VE
Sbjct: 216 GHIAAGTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEY 275
Query: 181 MRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGIN---MFPYVVYDKKH 237
MRRG PT A + ++RI H+P+F GAV+ G YGAAC+ ++ F ++VY+ +
Sbjct: 276 MRRGEDPTIACQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYNSEK 335
Query: 238 SSYQIVNVSC 247
+ V C
Sbjct: 336 NQPTEEKVDC 345
>UniRef50_UPI000155C291 Cluster: PREDICTED: similar to lysosomal
glycosylasparaginase; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to lysosomal glycosylasparaginase -
Ornithorhynchus anatinus
Length = 485
Score = 225 bits (550), Expect = 8e-58
Identities = 110/250 (44%), Positives = 148/250 (59%), Gaps = 4/250 (1%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
M +GAV GLRR+K+AI VAR V++HT+H+ LVGE ATQFA MGF E L+T+ S +
Sbjct: 236 MEVGAVAGLRRVKNAIGVARKVMEHTRHTLLVGESATQFAEAMGFPNEDLSTNHSASAYS 295
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
+W ++ CQPNFW NV PD +++CGPY+ + ++ HDTIGMV I +
Sbjct: 296 RWLRQN-CQPNFWKNVIPDASKSCGPYKPAGGLVQRKAPAPGKINLHGHDTIGMVVIGKS 354
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
G A+GTS+NGA +KI GR+GDSP+ G+G+Y M+RFLPS+ VE
Sbjct: 355 GHTASGTSSNGANHKIHGRVGDSPVAGAGSYADSTVGGAAATGDGDAMMRFLPSYQAVEY 414
Query: 181 MRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGI---NMFPYVVYDKKH 237
MR G P A K ++RI H P F GAV+ G YGAAC+ + + F ++VY
Sbjct: 415 MRAGDDPASACKKVISRIQRHVPHFFGAVICANITGGYGAACNKLPEFSQFRFMVYHSLQ 474
Query: 238 SSYQIVNVSC 247
S V C
Sbjct: 475 SQPSEEKVDC 484
>UniRef50_Q21697 Cluster: Putative
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
precursor (EC 3.5.1.26) (Glycosylasparaginase)
(Aspartylglucosaminidase) (N4-(N-
acetyl-beta-glucosaminyl)-L-asparagine amidase) (AGA)
[Contains: Glycosylasparaginase alpha chain;
Glycosylasparaginase beta chain]; n=2;
Caenorhabditis|Rep: Putative
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase
precursor (EC 3.5.1.26) (Glycosylasparaginase)
(Aspartylglucosaminidase) (N4-(N-
acetyl-beta-glucosaminyl)-L-asparagine amidase) (AGA)
[Contains: Glycosylasparaginase alpha chain;
Glycosylasparaginase beta chain] - Caenorhabditis
elegans
Length = 363
Score = 224 bits (547), Expect = 2e-57
Identities = 116/240 (48%), Positives = 148/240 (61%), Gaps = 10/240 (4%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
M +GAV L RI+ A VA V++ TKH+ LVGE ATQFA +GF+EE L+T +K
Sbjct: 95 MRVGAVANLHRIRDAARVAWGVMNFTKHTLLVGESATQFAKTLGFKEEDLSTEETKSWIS 154
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLN--------VDRFNHDTI 112
KW E CQPNFW NVSPDP+ +CGPY+ + + + S +N V++ NHDTI
Sbjct: 155 KWKTEK-CQPNFWKNVSPDPSSSCGPYKTNPLTKSMRYYSLVNQSDEAGYLVEKTNHDTI 213
Query: 113 GMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFL 172
GMV D +AGTS+NGA++KIPGR+GDSPIPG+GAY VM+RFL
Sbjct: 214 GMVVRDTENIFSAGTSSNGARFKIPGRVGDSPIPGAGAY-ANKFGGAAATGDGDVMMRFL 272
Query: 173 PSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINMFPYVV 232
PSF V +M G+ P+ AA A+ RI +P F GAVVA+ G GA+C IN F Y V
Sbjct: 273 PSFFAVTQMELGTKPSKAAYKAITRILKVFPKFSGAVVAMNVKGRIGASCANINKFGYNV 332
>UniRef50_Q5DGG1 Cluster: SJCHGC09117 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC09117 protein - Schistosoma
japonicum (Blood fluke)
Length = 359
Score = 210 bits (513), Expect = 2e-53
Identities = 112/254 (44%), Positives = 156/254 (61%), Gaps = 8/254 (3%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
M +GAV + I+ A VAR VL TKH+ LVG LA +FA G++ SL TS S LW+
Sbjct: 103 MEVGAVASMPDIRQASQVARDVLLSTKHTLLVGPLAAEFAKSRGYKPTSLDTSKSHNLWI 162
Query: 61 KWHNEHHCQPNFWLNVS--PDPTRNCGPYQKH--EYSHHLLKKSHLN-VDRFNHDTIGMV 115
KW +++CQPNF + PDP +CGPY+ + + + LK +N +D NHDTIG++
Sbjct: 163 KWQ-KNNCQPNFRKSADWVPDPVTSCGPYRTNVSDINSPKLKDQRINKLDINNHDTIGVI 221
Query: 116 AIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSF 175
A+D +G +A GTST+G+ YKIPGR+GDSPIPG+G Y +M+R+L SF
Sbjct: 222 ALDAYGSMAVGTSTSGSTYKIPGRVGDSPIPGAGGYVVDNIGGAVATGDGDLMMRYLLSF 281
Query: 176 LTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINMFPYVVYDK 235
V+ +R+G PT+A KTA+ + S ++ GA+VAL N GEYG+AC G F Y V
Sbjct: 282 QVVDYLRQGIGPTEACKTALRSVRSK-EEWYGALVALTNRGEYGSACVGFTDFKYSVRAS 340
Query: 236 -KHSSYQIVNVSCS 248
+ I+ VSC+
Sbjct: 341 WIGNQTNIIAVSCT 354
>UniRef50_UPI000023DB25 Cluster: hypothetical protein FG02189.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG02189.1 - Gibberella zeae PH-1
Length = 367
Score = 209 bits (511), Expect = 4e-53
Identities = 107/245 (43%), Positives = 146/245 (59%), Gaps = 7/245 (2%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
MN GAV LRR+K AISVARHVL++T HS L G+ ATQFA+E GF+ +LTT S K
Sbjct: 98 MNTGAVAALRRVKDAISVARHVLEYTSHSLLAGDQATQFAIENGFKTTNLTTKASAKKCK 157
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
+W CQPN+ LNVSP+P CGPY+ + +K+ + +HDT+ ++AI +
Sbjct: 158 EW-KASKCQPNYRLNVSPNPEHFCGPYRPLAKNKQTQQKT-----QSSHDTLSLIAITKE 211
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
G +AAGT+TNGA +KIPGR+GD PI GSG+Y +MLRFLP + ++
Sbjct: 212 GSLAAGTTTNGASHKIPGRVGDGPIVGSGSYADSSIGGCGATGDGDIMLRFLPCYQALDS 271
Query: 181 MRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINMFPYVVYDKKHSSY 240
+ RG SP +AA+ AV R+ Y D +V + G +GAA G + F Y K
Sbjct: 272 LSRGLSPKEAAEDAVLRMVRKYSDLKSGIVVVDRYGNHGAAASGWD-FTYSYRGGKMKKT 330
Query: 241 QIVNV 245
++V V
Sbjct: 331 KVVKV 335
>UniRef50_Q9W2C3 Cluster: CG4372-PA; n=2; Sophophora|Rep: CG4372-PA
- Drosophila melanogaster (Fruit fly)
Length = 397
Score = 194 bits (474), Expect = 1e-48
Identities = 97/250 (38%), Positives = 142/250 (56%), Gaps = 4/250 (1%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+ GAV G+ +++AI VA VL +TKHS LVG+ AT+FA +G++EE LT + ++ +
Sbjct: 123 LEYGAVAGMNGVRNAILVADAVLKYTKHSVLVGKSATKFARSLGYKEEYLTDARTRNVLK 182
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQK-HEYSHHLLKKSHLNVDRFNHDTIGMVAIDQ 119
KW + + CQPNFW +V P P NCGPY E+ H + + HD + +A+D
Sbjct: 183 KWRS-NGCQPNFWRDVHPSPAENCGPYSPLPEHMHQHPMHQEYAIIQGQHDQLAFLALDA 241
Query: 120 HGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVE 179
G + ++GA+++IPGR+GDS +PG+G Y V++R LP+FL VE
Sbjct: 242 EGKFHVASQSSGAQFRIPGRVGDSAVPGAGIYADNEVGGAVASGDGDVLMRHLPAFLAVE 301
Query: 180 EMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINMFPYVVYDKKH-- 237
MR G P AA+ V R+ H +F GAVV + G Y AAC G++ F +VV K
Sbjct: 302 AMRAGKEPDKAAELVVQRLLRHNTEFNGAVVVVNRRGIYAAACAGLDEFHFVVSGGKEYL 361
Query: 238 SSYQIVNVSC 247
S ++ V C
Sbjct: 362 SMARVERVKC 371
>UniRef50_Q56W64 Cluster: Probable L-asparaginase 3 precursor (EC
3.5.1.1) (L-asparagine amidohydrolase 3) [Contains:
L-asparaginase 3 subunit alpha; L- asparaginase 3
subunit beta]; n=11; Eukaryota|Rep: Probable
L-asparaginase 3 precursor (EC 3.5.1.1) (L-asparagine
amidohydrolase 3) [Contains: L-asparaginase 3 subunit
alpha; L- asparaginase 3 subunit beta] - Arabidopsis
thaliana (Mouse-ear cress)
Length = 359
Score = 188 bits (457), Expect = 2e-46
Identities = 106/259 (40%), Positives = 145/259 (55%), Gaps = 18/259 (6%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEE-SLTTSVSKKLW 59
M +GAV +R +K I A V+ +++H+ L GE A+ FA+ MG +L++ S K W
Sbjct: 103 MEVGAVAAMRYVKDGIRAAHLVMKYSQHTLLAGEGASAFAISMGLPGPMNLSSPESVKKW 162
Query: 60 MKWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHL-LKKSHLN------------VDR 106
W E+ CQPNF NV P +CGPY+ + + ++ + KS + V
Sbjct: 163 SDW-KENQCQPNFRKNVVP--ANDCGPYKPNNSAMNVFVDKSTESCEMGAIEYKPPLVGP 219
Query: 107 FNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXX 166
NHDTI M ID+ G IA GTSTNGA YKIPGR+GD PI GS AY
Sbjct: 220 HNHDTISMAVIDRMGHIAVGTSTNGATYKIPGRVGDGPIVGSSAYADDEVGGCGATGDGD 279
Query: 167 VMLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGIN 226
M+RFLP + VE MR+G P +AAK A++RIA +PDF+GAVVA+ +G + AC+G
Sbjct: 280 TMMRFLPCYQVVESMRQGMKPEEAAKDAISRIARKFPDFVGAVVAVDKNGSHAGACYGWT 339
Query: 227 MFPYVVYDKKHSSYQIVNV 245
F Y V + + Q+ V
Sbjct: 340 -FQYSVQNPDMNDVQVFTV 357
>UniRef50_UPI0000E484F2 Cluster: PREDICTED: similar to LOC496249
protein, partial; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to LOC496249 protein,
partial - Strongylocentrotus purpuratus
Length = 390
Score = 181 bits (441), Expect = 1e-44
Identities = 99/216 (45%), Positives = 130/216 (60%), Gaps = 19/216 (8%)
Query: 3 IGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKW 62
+G+VGGLRRIK AISVAR V+ +T + LVGE AT+FA+EMGFQ+E+LTT+ S
Sbjct: 56 VGSVGGLRRIKSAISVARAVMMYTTETLLVGESATKFAIEMGFQQENLTTNRSSPYL--- 112
Query: 63 HNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGD 122
C P L + T + G Y ++++ NHDTIGM+ ID G
Sbjct: 113 ---GSCGPYTPLKANDLKTSSRGRYNS-------------DINKNNHDTIGMIVIDSDGH 156
Query: 123 IAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMR 182
IA GTSTNGA +K+PGR+GDSPI GSGAY VM+RFLPS+ VE +R
Sbjct: 157 IAGGTSTNGANHKVPGRVGDSPITGSGAYVDRDVGGAAGTGDGDVMMRFLPSYQVVENLR 216
Query: 183 RGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEY 218
G +P A ++A+ RI ++PDF GA++A DG Y
Sbjct: 217 NGMAPDKACQSALQRIIKYHPDFSGALIAATIDGNY 252
Score = 112 bits (269), Expect = 9e-24
Identities = 52/110 (47%), Positives = 68/110 (61%)
Query: 139 RIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMRRGSSPTDAAKTAVARI 198
R+GDSPI GSGAY VM+RFLPS+ VE +R G SP A ++A+ RI
Sbjct: 274 RVGDSPITGSGAYVDRDVGGAAGTGDGDVMMRFLPSYQVVENLRNGMSPDKACQSALQRI 333
Query: 199 ASHYPDFMGAVVALKNDGEYGAACHGINMFPYVVYDKKHSSYQIVNVSCS 248
++PDF GA++A DG+YGAACHG + F Y V + SS Q++ V CS
Sbjct: 334 IKYHPDFSGALIAATIDGQYGAACHGFSSFHYSVRNPSMSSVQVLEVPCS 383
Score = 37.9 bits (84), Expect = 0.24
Identities = 15/26 (57%), Positives = 23/26 (88%)
Query: 33 GELATQFAVEMGFQEESLTTSVSKKL 58
G AT+FA+EMGFQ+E+LTT+ S+++
Sbjct: 250 GNYATKFAIEMGFQQENLTTNRSRRV 275
>UniRef50_A6C783 Cluster: Asparaginase; n=1; Planctomyces maris DSM
8797|Rep: Asparaginase - Planctomyces maris DSM 8797
Length = 343
Score = 123 bits (297), Expect = 4e-27
Identities = 83/223 (37%), Positives = 114/223 (51%), Gaps = 27/223 (12%)
Query: 2 NIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMK 61
N G+VG L IK SVAR V++ T H LVGE A QFA GF+EE+L T S+K+W++
Sbjct: 110 NCGSVGALENIKTPSSVARLVMERTDHIHLVGEGARQFARAHGFKEENLLTDKSRKMWLR 169
Query: 62 WHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHG 121
W E+ + WL P ++ G Y ++D+ TI ++A+D G
Sbjct: 170 W-KENLSDKDDWL-----PPKD-GNY---------------DLDKRPTGTINILALDSKG 207
Query: 122 DIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEM 181
D+A T+T+G K+PGRIGDSPI G+G Y +LR SF VE+M
Sbjct: 208 DLAGCTTTSGLFGKLPGRIGDSPIIGAGLYVDNEVGAAGATGRGEEILRTCGSFFVVEQM 267
Query: 182 RRGSSPTDAAKTAVARIAS-----HYPDFMGAVVALKNDGEYG 219
R G SP +A + RI DF +VA+ +GE G
Sbjct: 268 RAGKSPREACQALCERIVKINGGPDKVDFNDKIVAINKNGEAG 310
>UniRef50_Q47898 Cluster:
N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase
precursor (EC 3.5.1.26) (Glycosylasparaginase)
(Aspartylglucosaminidase) (N4-(N-
acetyl-beta-glucosaminyl)-L-asparagine amidase) (AGA)
[Contains: Glycosylasparaginase alpha chain;
Glycosylasparaginase beta chain]; n=15; Bacteria|Rep:
N(4)-(Beta-N-acetylglucosaminyl)-L-asparaginase
precursor (EC 3.5.1.26) (Glycosylasparaginase)
(Aspartylglucosaminidase) (N4-(N-
acetyl-beta-glucosaminyl)-L-asparagine amidase) (AGA)
[Contains: Glycosylasparaginase alpha chain;
Glycosylasparaginase beta chain] - Elizabethkingia
miricola (Chryseobacterium miricola)
Length = 340
Score = 121 bits (292), Expect = 1e-26
Identities = 83/242 (34%), Positives = 124/242 (51%), Gaps = 40/242 (16%)
Query: 2 NIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMK 61
NIG+V + IK+ ISVAR V++ T H LVG+ A +FA+ GF++E+L T+ S+K W +
Sbjct: 120 NIGSVACMEHIKNPISVARAVMEKTPHVMLVGDGALEFALSQGFKKENLLTAESEKEWKE 179
Query: 62 WHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHG 121
WL S +Y K +N++ NHDTIGM+A+D G
Sbjct: 180 -----------WLKTS-------------QY------KPIVNIE--NHDTIGMIALDAQG 207
Query: 122 DIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEM 181
+++ +T+G YK+ GR+GDSPI G+G + ++R + + L VE M
Sbjct: 208 NLSGACTTSGMAYKMHGRVGDSPIIGAGLFVDNEIGAATATGHGEEVIRTVGTHLVVELM 267
Query: 182 RRGSSPTDAAKTAVARI-------ASHYPDFMGAVVALKNDGEYGAACHGINMFPYVVYD 234
+G +P A K AV RI + D +AL GEYGA C + F + V+D
Sbjct: 268 NQGRTPQQACKEAVERIVKIVNRRGKNLKDIQVGFIALNKKGEYGAYCIQ-DGFNFAVHD 326
Query: 235 KK 236
+K
Sbjct: 327 QK 328
>UniRef50_Q2GPW6 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 378
Score = 121 bits (291), Expect = 2e-26
Identities = 60/138 (43%), Positives = 82/138 (59%), Gaps = 1/138 (0%)
Query: 108 NHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXV 167
+HDTI MV ID+ G +AAGTSTNGA +KIPGR+GD PI GSG+Y +
Sbjct: 229 SHDTISMVVIDREGGMAAGTSTNGAAFKIPGRVGDGPIVGSGSYVDRDVGGCGATGDGDI 288
Query: 168 MLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINM 227
M+RFLP + VE +R G +PT+AA+ AV R+ YP+ +V + N E+GAA G
Sbjct: 289 MMRFLPCYQAVENLRLGMTPTEAAEDAVRRMLRKYPNISSGLVVVNNKAEHGAAGSGWT- 347
Query: 228 FPYVVYDKKHSSYQIVNV 245
F Y ++ ++V V
Sbjct: 348 FTYAFRGGAMNATEVVTV 365
Score = 69.3 bits (162), Expect = 8e-11
Identities = 32/44 (72%), Positives = 38/44 (86%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMG 44
M GAV GLRRI+ A++VAR VLDHT+HS LVG+LAT+FAVEMG
Sbjct: 118 MKSGAVAGLRRIRDAVAVARAVLDHTRHSLLVGDLATRFAVEMG 161
>UniRef50_A2TS29 Cluster: Asparaginase; n=9; Bacteroidetes|Rep:
Asparaginase - Dokdonia donghaensis MED134
Length = 337
Score = 120 bits (288), Expect = 5e-26
Identities = 86/244 (35%), Positives = 120/244 (49%), Gaps = 39/244 (15%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
GAV + I + ++AR V++ T H L G+ A +FA + GF++E+L T K W +
Sbjct: 120 GAVLAVENIVNVAALARKVMEDTPHVILAGKGAEEFAYQQGFKKENLLTEERKNAWQE-- 177
Query: 64 NEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGDI 123
WL S +Y K +N++ NHDTIGM+AID+ GDI
Sbjct: 178 ---------WLKTS-------------DY------KPEINIE--NHDTIGMLAIDKDGDI 207
Query: 124 AAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMRR 183
A +T+G YK+ GR+GDSPI GSG + +L+ + SFL VE MR
Sbjct: 208 AGVCTTSGLGYKMKGRVGDSPIIGSGLFIDNEVGGAVATGMGEEVLKTVGSFLIVELMRG 267
Query: 184 GSSPTDAAKTAVARIAS---HYPDFMGAVVALKNDGEYGAAC--HGINMFPYVVYDKKH- 237
G SP A + A+ RI Y DF A +A+ GE G+ C G M Y + K+
Sbjct: 268 GMSPQKACEEAITRITKKGPRYKDFQIAYIAINKSGEAGSHCIHKGFTMMKYQNGENKNI 327
Query: 238 -SSY 240
SSY
Sbjct: 328 TSSY 331
>UniRef50_Q7S2Q8 Cluster: Putative uncharacterized protein
NCU09718.1; n=1; Neurospora crassa|Rep: Putative
uncharacterized protein NCU09718.1 - Neurospora crassa
Length = 314
Score = 116 bits (280), Expect = 4e-25
Identities = 70/162 (43%), Positives = 97/162 (59%), Gaps = 12/162 (7%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
++ GAV LRR++ AI+VA+ VL +T+HS L G+ AT+FA E GF EE L T S+ +
Sbjct: 139 LDSGAVANLRRVRDAIAVAKRVLLYTRHSLLTGDQATEFARENGFAEEDLGTEESRAVCE 198
Query: 61 KWHNEHHCQPNFWLNVSPDPTRN------CGPY----QKHEYSHHLLKKSH--LNVDRFN 108
W E + ++ NV + CGP+ +K + L +S+ L R
Sbjct: 199 NWKREGCKKGSYRRNVVVGEGKGEGEGGACGPFVPVPEKDLGADGGLGESNKQLGEKRGG 258
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGA 150
HDTI M+AI + G +AAG+STNGA +KIPGR+GD PI GSGA
Sbjct: 259 HDTISMIAIGKDGRMAAGSSTNGASHKIPGRVGDGPIVGSGA 300
>UniRef50_Q02BR8 Cluster: Peptidase T2, asparaginase 2; n=1;
Solibacter usitatus Ellin6076|Rep: Peptidase T2,
asparaginase 2 - Solibacter usitatus (strain Ellin6076)
Length = 400
Score = 110 bits (265), Expect = 3e-23
Identities = 74/228 (32%), Positives = 107/228 (46%), Gaps = 13/228 (5%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
GAVG LR IK +A+ V+ T H LVGE A +FA G+ EE L T S+ W W
Sbjct: 134 GAVGALRGIKTPSKIAQLVMAETDHMMLVGEGALRFAKAWGYAEEDLLTDRSRLAWRMWK 193
Query: 64 NEHHCQ---PNFWLNVSPDPTRNCGPYQKH---EYSHHLLKKSHLNVDRFNHDTIGMVAI 117
E + N+ + P + +K L + ++ H TI +A+
Sbjct: 194 REMRDRGGHTNWESSTDAPPAKKMAELKKAFPGADEESLAWAYEIALNPPPHGTINCLAL 253
Query: 118 DQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLT 177
++ G+++A T+T+GA +KIPGR+GDSPI G G + LR +
Sbjct: 254 NEKGEMSAVTTTSGAAFKIPGRLGDSPIIGGGMWLDQDIGAAGSTGRGEENLRVCGAHTI 313
Query: 178 VEEMRRGSSPTDAAKTAVARIASHYPDFMGAVV-------ALKNDGEY 218
VE MR+G P DA A R+A ++ + G + AL DGEY
Sbjct: 314 VENMRQGMRPKDAILDAFKRVARNFDNDAGRLAQIDLNFYALNKDGEY 361
>UniRef50_A4A1V3 Cluster: Asparaginase; n=1; Blastopirellula marina
DSM 3645|Rep: Asparaginase - Blastopirellula marina DSM
3645
Length = 322
Score = 107 bits (256), Expect = 3e-22
Identities = 65/198 (32%), Positives = 100/198 (50%), Gaps = 8/198 (4%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
G+V GL+ ++HA VAR V+ T+ + L G+ A +FA GF EE+L T ++++W+ W
Sbjct: 79 GSVIGLKGVRHAAQVARLVMQQTRRAMLCGDGALEFARANGFVEENLLTEKARQIWLYW- 137
Query: 64 NEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGDI 123
C+ WL P P G + E + + ++ + T+ + A D D+
Sbjct: 138 KRLECRGKDWL--PPQP----GEFDA-ETIAEFERYYPVTGEKASGGTVHLAARDAGSDM 190
Query: 124 AAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMRR 183
A T+T+G +K+PGR+GDSPI G+G Y L SF V +M R
Sbjct: 191 ACATTTSGHCFKMPGRVGDSPIFGAGLYVDNEMGTCGSVGHGEANLLNCSSFQAVYQMGR 250
Query: 184 GSSPTDAAKTAVARIASH 201
G+SP DA +A +A H
Sbjct: 251 GASPVDAGLETLAMVAKH 268
>UniRef50_Q15ZN1 Cluster: Twin-arginine translocation pathway signal
precursor; n=1; Pseudoalteromonas atlantica T6c|Rep:
Twin-arginine translocation pathway signal precursor -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 327
Score = 104 bits (250), Expect = 2e-21
Identities = 51/128 (39%), Positives = 79/128 (61%), Gaps = 5/128 (3%)
Query: 98 KKSHLNVDRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXX 157
+K +N++ NHDTIGM+A+D G+++ +T+GA +K+PGR+GDSPI G+G Y
Sbjct: 174 QKKQINIE--NHDTIGMLALDASGNLSGACTTSGAAFKLPGRVGDSPIIGAGLYVDNEVG 231
Query: 158 XXXXXXXXXVMLRFLPSFLTVEEMRRGSSPTDAAKTAVARIAS---HYPDFMGAVVALKN 214
+M++ + L VE MR+G+SP +A + AV RIA+ ++ +F +AL
Sbjct: 232 AATATGMGELMMKTVGCHLVVELMRQGASPQEACQKAVERIATRLDNFAEFQVGFLALNK 291
Query: 215 DGEYGAAC 222
GEYGA C
Sbjct: 292 AGEYGAYC 299
Score = 66.5 bits (155), Expect = 6e-10
Identities = 32/62 (51%), Positives = 42/62 (67%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
MN G+V L+ I H ISVAR V+++T H LVG A +FAVE GF E++L T SK+ W+
Sbjct: 107 MNCGSVAYLQDILHPISVARKVMENTPHVMLVGAGAKKFAVEQGFAEQNLLTEQSKQDWL 166
Query: 61 KW 62
W
Sbjct: 167 AW 168
>UniRef50_A1RYG2 Cluster: Peptidase T2, asparaginase 2; n=1;
Thermofilum pendens Hrk 5|Rep: Peptidase T2,
asparaginase 2 - Thermofilum pendens (strain Hrk 5)
Length = 319
Score = 98.7 bits (235), Expect = 1e-19
Identities = 70/220 (31%), Positives = 104/220 (47%), Gaps = 27/220 (12%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+++GAV LRR +A+S+AR V++ T H LVG A A +GF
Sbjct: 96 LSVGAVASLRRTWNAVSLARVVMEKTDHVLLVGPGADALAERLGF--------------- 140
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYS--HHLLKKSHLNVDRFNHDTIGMVAID 118
E H P SP R Y++ S ++L +++ + F DT+G VAID
Sbjct: 141 ----EPHPGP------SPRALRRYEEYRRLLASKEYYLWSRNYSVAEVFLGDTVGAVAID 190
Query: 119 QHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTV 178
G++AA TST G K+PGR+GDSPIPG+G Y V+LR +
Sbjct: 191 SEGNLAAATSTGGLFLKLPGRVGDSPIPGAGVYAENGVVAVSATGIGEVILRSTLAARIA 250
Query: 179 EEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEY 218
+R G+ DA + V+ + S + + V+A+ G Y
Sbjct: 251 SLVRSGARVEDALREVVSSVTSKFGENTVGVIAIDGSGSY 290
>UniRef50_Q1IU43 Cluster: Peptidase T2, asparaginase 2 precursor;
n=1; Acidobacteria bacterium Ellin345|Rep: Peptidase T2,
asparaginase 2 precursor - Acidobacteria bacterium
(strain Ellin345)
Length = 402
Score = 97.9 bits (233), Expect = 2e-19
Identities = 67/217 (30%), Positives = 101/217 (46%), Gaps = 19/217 (8%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
G+VGG+ I H +A+ V++HT H LVGE A +FAV GF +L T S+K+W+ W
Sbjct: 111 GSVGGVHDIMHVALLAKTVMEHTGHVMLVGEGAKRFAVAHGFPTMNLLTEHSRKVWLLW- 169
Query: 64 NEHHCQPNFWLN--VSPD---PTRNCGPYQKHEYSHHLLKKSH----------LNVDRFN 108
E + ++W SP PT E + K + + R
Sbjct: 170 KETNSNQDWWGPGPASPHFKFPTNGTKSEDLKERIREMEKLAEQIGIEPERRMAAIHRVL 229
Query: 109 HDTIGMV---AIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXX 165
+ G + A+ +G+++ T+T+G +KIPGR GDSPI G+G Y
Sbjct: 230 YPPTGTINCSALKANGEMSGATTTSGLAWKIPGRCGDSPIIGAGCYCDQDVGSAGATGSG 289
Query: 166 XVMLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHY 202
++ + VE MR G SP +A A+ RI +Y
Sbjct: 290 EENIKIAGAHTIVENMRHGMSPKEAGMDALKRIVRNY 326
>UniRef50_Q2RZ81 Cluster: Asparaginase; n=1; Salinibacter ruber DSM
13855|Rep: Asparaginase - Salinibacter ruber (strain DSM
13855)
Length = 311
Score = 95.1 bits (226), Expect = 1e-18
Identities = 71/230 (30%), Positives = 106/230 (46%), Gaps = 28/230 (12%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
GAV L I VAR V++ T H LVG A +FA GF+ + L T ++++W++W
Sbjct: 70 GAVAVLEDIPVPSQVARLVMERTDHVRLVGTGAKEFAKMHGFETQDLLTEQARRIWVEWK 129
Query: 64 NEHHCQPNFWLNVSPDPTRNCGPYQK-HEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGD 122
+ N+ + PD ++ +K E H + TI A+ +G+
Sbjct: 130 ENLSQEDNY---LPPDSLKDPALGEKVREVQRH-------------YGTIHCSALAPNGN 173
Query: 123 IAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMR 182
I A T+T+G YKIPGR+ D+ + G+G Y L+ L S+L VE MR
Sbjct: 174 IGAVTTTSGLFYKIPGRVADTSVVGAGLYADNDVGAAGSTGRGEANLKNLSSYLIVERMR 233
Query: 183 RGSSPTDAAKTAVARIASH-----------YPDFMGAVVALKNDGEYGAA 221
G +P +A A RIA + P+F AL+ DG +G A
Sbjct: 234 DGDTPEEACLFACRRIAENTQVPRLLNAQDEPNFGVRFYALRKDGAFGGA 283
>UniRef50_Q08CE9 Cluster: Zgc:153169; n=5; Danio rerio|Rep:
Zgc:153169 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 274
Score = 93.9 bits (223), Expect = 3e-18
Identities = 49/134 (36%), Positives = 73/134 (54%), Gaps = 5/134 (3%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVM 168
HDTIG++A+D G+I G ST+GA +K+PGR+GDSP+PG G Y +
Sbjct: 133 HDTIGLIALDLSGNITVGVSTSGAPFKLPGRVGDSPLPGCGLYADHTVGAAAATGDGDKI 192
Query: 169 LRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPD---FMGAVVALKNDGEYGAACHGI 225
+ + PSF V+ M++GSSP +A +A I F +++L GE GAA
Sbjct: 193 MCYCPSFHVVQLMKQGSSPNEACSAVLADIQRRMGGNQCFEIGLISLNLKGEVGAA--SS 250
Query: 226 NMFPYVVYDKKHSS 239
FPY ++++ S
Sbjct: 251 VEFPYTFWNQELDS 264
Score = 43.6 bits (98), Expect = 0.005
Identities = 22/45 (48%), Positives = 27/45 (60%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEE 48
GAV LR I VAR V++ + HS LVGE A FA ++GF E
Sbjct: 61 GAVAALRGIPQPCRVARKVMEESPHSLLVGEGAKAFAQDLGFTSE 105
>UniRef50_A0X701 Cluster: Peptidase T2, asparaginase 2 precursor;
n=2; Shewanella|Rep: Peptidase T2, asparaginase 2
precursor - Shewanella pealeana ATCC 700345
Length = 361
Score = 91.1 bits (216), Expect = 2e-17
Identities = 56/157 (35%), Positives = 82/157 (52%), Gaps = 9/157 (5%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTT--SVSKKL 58
MN GAV G++ IK+ I +A V++ + H L G+ A +FA+ GFQ + + + S+
Sbjct: 113 MNAGAVAGVKHIKNPIDLAMTVMEKSPHVMLSGQGAEEFALTQGFQLVPVNSFDTESRYQ 172
Query: 59 WMKWHNEH----HCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGM 114
+K E P + + + GP H Y L S + + T+G
Sbjct: 173 QLKSAKEKIQKAESSPEYQASTGLSTGSSTGPNSHHNYKQSALDYSEFD---YKFGTVGA 229
Query: 115 VAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
VA+DQ+G++AAGTST G K GRIGDSPI G+G Y
Sbjct: 230 VALDQNGNLAAGTSTGGMTAKRFGRIGDSPIIGAGTY 266
>UniRef50_A3HZD4 Cluster: Asparaginase; n=1; Algoriphagus sp.
PR1|Rep: Asparaginase - Algoriphagus sp. PR1
Length = 326
Score = 89.0 bits (211), Expect = 1e-16
Identities = 45/126 (35%), Positives = 71/126 (56%), Gaps = 6/126 (4%)
Query: 99 KSHLNVDRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXX 158
K +N++ NHDTIGM+ +D+ G++A +T+G YK+ GR+GDSPI G+G +
Sbjct: 177 KPIINIE--NHDTIGMIGLDKDGNLAGSCTTSGLAYKMHGRVGDSPIIGAGLFVDNEVGA 234
Query: 159 XXXXXXXXVMLRFLPSFLTVEEMRRGSSPTDAAKTAVARIAS----HYPDFMGAVVALKN 214
+++ SF+ VE MR+G +P +A + AV R+ S + D +A+
Sbjct: 235 ATATGLGESIIKVCGSFMIVELMRQGRTPQEACEEAVRRLISKNKGNIKDIQAGFLAINK 294
Query: 215 DGEYGA 220
DGE GA
Sbjct: 295 DGEVGA 300
Score = 51.2 bits (117), Expect = 2e-05
Identities = 26/69 (37%), Positives = 44/69 (63%), Gaps = 3/69 (4%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGF--QEESLTTSVSKKLWMK 61
G+V +R++KH +S+AR V++ T H +VGE A Q A+ GF ++E L+ + +KK + K
Sbjct: 111 GSVAFVRQVKHPVSLARVVMEKTPHVMIVGEGARQLAISEGFPIEKEELSPN-AKKAYEK 169
Query: 62 WHNEHHCQP 70
W + +P
Sbjct: 170 WKVQSQYKP 178
>UniRef50_A6D1A2 Cluster: Asparaginase; n=1; Vibrio shilonii
AK1|Rep: Asparaginase - Vibrio shilonii AK1
Length = 318
Score = 86.6 bits (205), Expect = 5e-16
Identities = 68/220 (30%), Positives = 95/220 (43%), Gaps = 18/220 (8%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+ GAVG ++ H +A+ V++ H LVGE AT+FA EMGF+ + SK++W
Sbjct: 70 LRTGAVGAVKDHFHVTRIAKKVMEELNHEILVGEGATRFAYEMGFECPNPLLEDSKEVWF 129
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
K E + N P + P HL S + DT + D
Sbjct: 130 KKLQEITGEDN--------PDMSTRPLA------HL--NSMITDPEKVRDTTVFLTKDST 173
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
I A TST+G +K PGR+GDSPI G+G Y + +R S+ V
Sbjct: 174 DSIYAATSTSGWAWKYPGRLGDSPIVGAGFYADSRYGAAACTHTGEMTIRANTSYSIVMA 233
Query: 181 MRRGSSPTDAAKTAVARIASHYPDFMGAVV--ALKNDGEY 218
MR G S A A+ + S F+ VV A+ D Y
Sbjct: 234 MRLGFSLDQAVDMAIEELNSLRTGFLAGVVIHAIDKDDNY 273
>UniRef50_A7T1K5 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 352
Score = 83.4 bits (197), Expect = 5e-15
Identities = 61/230 (26%), Positives = 106/230 (46%), Gaps = 29/230 (12%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGF---QEESLTTSVSKK 57
++ GAV ++ + + +S+ARHV+ T H LV E A +FA ++ + +S+T+ S+
Sbjct: 117 LDAGAVACVKGVVNPVSLARHVMTDTPHCMLVSEGAVKFAQDLDLPMVEPQSMTSEFSR- 175
Query: 58 LWMKWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAI 117
F ++ +P L+ + L+ HDT+G VA+
Sbjct: 176 --------------FKASLRNNPNATF---------EDALRMTRLSKSLPEHDTVGAVAM 212
Query: 118 DQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLT 177
D HG+IA TST G K+ GR+GDSP+PGSG Y + ++ + +
Sbjct: 213 DCHGNIACATSTGGLFKKMCGRVGDSPMPGSGGYASKEGGASTTGHGESI-IKVVLAREV 271
Query: 178 VEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINM 227
+ ++ G S DA + ++ + G V+++ G YG A + M
Sbjct: 272 IYQLEDGKSVNDACTNGINKMFT-LTGGQGGVISIDKHGNYGKAFSTLGM 320
>UniRef50_Q1IU95 Cluster: Peptidase T2, asparaginase 2; n=3;
Bacteria|Rep: Peptidase T2, asparaginase 2 -
Acidobacteria bacterium (strain Ellin345)
Length = 308
Score = 82.6 bits (195), Expect = 8e-15
Identities = 63/221 (28%), Positives = 98/221 (44%), Gaps = 25/221 (11%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+ G VG + R+ + I AR VL + H + VGE A +FA E G + + ++ +
Sbjct: 88 LQAGGVGCVERLMNPIRAARKVLSDSPHIYFVGEGAERFAEEHGIALCANEELIIERELV 147
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
+W + Q +L V P+ GP +D HDT+G VA+D
Sbjct: 148 RWKDAKKQQ---FLKV---PSEFAGP----------------GMD--THDTVGAVALDAQ 183
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
G+IAAGTST G K GR+GDS + G G Y M++ + S +
Sbjct: 184 GNIAAGTSTGGTLNKAAGRVGDSSLIGCGGYADNLSAAVSVTGWGEPMMKLVLSKWAADR 243
Query: 181 MRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAA 221
+ G +P A A+ R+ + + G ++ L + G G A
Sbjct: 244 VEMGDAPQTVATAAIERLYTRL-NGHGGIILLDSKGRIGLA 283
>UniRef50_A1VC55 Cluster: Peptidase T2, asparaginase 2; n=4;
Bacteria|Rep: Peptidase T2, asparaginase 2 -
Desulfovibrio vulgaris subsp. vulgaris (strain DP4)
Length = 315
Score = 82.6 bits (195), Expect = 8e-15
Identities = 59/223 (26%), Positives = 100/223 (44%), Gaps = 21/223 (9%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
++ G V +RR + + +AR +LD T+ LVGE A +FA+E G + T + ++ +
Sbjct: 87 LDFGGVAAVRRFANPVDIARRLLD-TEFCLLVGEGAERFALEQGLKPVDPATLLVERERL 145
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
+ + R+ Y H+ + + T+G VA+D H
Sbjct: 146 LY----------------ETLRSRAGYSTHDAFRPVTDTAPAG--SVPKGTVGAVALDIH 187
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
G++AA TST G +K+ GR+GDSP+ G+G Y ++R L + E
Sbjct: 188 GNVAAATSTGGTPFKLAGRVGDSPLCGAGTYADNETGGASATGFGEGVMRTLMTHCACEH 247
Query: 181 MRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACH 223
+R P +AA+ A+ + G ++ L G YG C+
Sbjct: 248 LRE-CLPDEAARRAIDMLHRRVGGHAG-LIMLDRHGRYGVHCN 288
>UniRef50_A5UPJ1 Cluster: Asparaginase; n=2; Roseiflexus|Rep:
Asparaginase - Roseiflexus sp. RS-1
Length = 325
Score = 81.8 bits (193), Expect = 1e-14
Identities = 60/224 (26%), Positives = 106/224 (47%), Gaps = 14/224 (6%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQ---EESLTTSVSKKLWM 60
GAV +R I++ IS+AR VL+ ++ + LVG A +FA +G + +E + + W
Sbjct: 89 GAVAAVRGIRNPISLARRVLE-SEAALLVGRGAERFADTVGIERCADEDMIVPRERARWE 147
Query: 61 KWHN-EHHCQPNFWLNVSPDPT--RNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAI 117
+ + P+ + + R H H L+ H DT+G VA+
Sbjct: 148 ELRRLAAYRTPDAFQRPPGEVAGLRGIVAGGDHAPDHPGLRIQHPG------DTVGAVAL 201
Query: 118 DQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLT 177
D++G++AA ST G +K+PGR+GD+P+ G+G Y +++ L +
Sbjct: 202 DRYGNLAAAVSTGGTPFKLPGRVGDTPLIGAGLYADVQTGGCASTGWGESIIKVLLAKTA 261
Query: 178 VEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAA 221
+ + G +P +AA+ A+ R+ +G V+ + G G A
Sbjct: 262 TDFLGAGYAPVEAARAAIERLEQRVHG-LGGVILIDVRGRVGYA 304
>UniRef50_Q8U4E6 Cluster: Putative L-asparaginase; n=4;
Thermococcaceae|Rep: Putative L-asparaginase -
Pyrococcus furiosus
Length = 306
Score = 81.8 bits (193), Expect = 1e-14
Identities = 70/223 (31%), Positives = 102/223 (45%), Gaps = 25/223 (11%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
++ GAV G+ +K+ ISVAR V++ T H L+GE A +FA MGF E TT +K W
Sbjct: 85 LDAGAVAGIWGVKNPISVARKVMEKTDHVLLIGEGAVKFARLMGFPEYDPTTEERRKQWE 144
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
+ + G + + L+K+ + V R T+G VA D
Sbjct: 145 ELRKK---------------LLETGEIRHWKKLSELIKE-YPEVLR---STVGAVAFDGE 185
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
+I AGTST G K+ GR+GD+PI G+G Y + L T +
Sbjct: 186 -EIVAGTSTGGVFLKMFGRVGDTPIIGAGTYANEVAGASCTGLGEVAIKLSLAK--TATD 242
Query: 181 MRRGSSPTDAAKTAVARIASHY--PDFMGAVVALKNDGEYGAA 221
R AA A R+A+ Y PD MG ++ + ++G G A
Sbjct: 243 FVRLGLDAQAASEAAIRLATKYFGPDTMG-IIMVDSNGNVGFA 284
>UniRef50_A4WD66 Cluster: Peptidase T2, asparaginase 2; n=10;
Bacteria|Rep: Peptidase T2, asparaginase 2 -
Enterobacter sp. 638
Length = 319
Score = 81.4 bits (192), Expect = 2e-14
Identities = 66/234 (28%), Positives = 102/234 (43%), Gaps = 38/234 (16%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
GAVG L I + I VA + +S LVG+ A ++A+ GF ++++ T + + H
Sbjct: 75 GAVGNLVDIANPIRVAHALSRQRYNSLLVGQGAREWALSQGFTDKTMLTDRALQ-----H 129
Query: 64 NEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGDI 123
C+ + PY H DT+G++ +D HG +
Sbjct: 130 YRKRCRETL--------DKGLSPYNGH-------------------DTVGIIGLDNHGSM 162
Query: 124 AAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMRR 183
+ TST+G K GR+GDSPI GSG Y +++ S+ V M +
Sbjct: 163 SVATSTSGLFMKKRGRLGDSPIIGSGFYCDSETGAATATGVGEDLMKGCTSYEIVRRMAQ 222
Query: 184 GSSPTDAAKTAVARIASHYPDFMG-----AVVALKNDGEYGAACHGINMFPYVV 232
G +P AA + V + G +VV + N GE+GAA + I F +VV
Sbjct: 223 GMTPQQAADSVVFELEDKLMSRFGRVGDLSVVCMNNKGEFGAATN-IKTFSFVV 275
>UniRef50_A3UJ27 Cluster: Asparaginase; n=1; Oceanicaulis alexandrii
HTCC2633|Rep: Asparaginase - Oceanicaulis alexandrii
HTCC2633
Length = 331
Score = 79.4 bits (187), Expect = 8e-14
Identities = 64/221 (28%), Positives = 97/221 (43%), Gaps = 13/221 (5%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
M GAV G+ ++H IS+AR VL+++ H L E A FA + + + +++
Sbjct: 97 MQAGAVAGVTNVRHPISLARAVLENSPHVMLQSEGAEAFAADQDLELVDNSYFFTER--- 153
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
+W + L V P P P E + L+++ H T+G+VA D
Sbjct: 154 RWASMVRAVRQLGLPVPPRPEGAPDPEPIREGALDLMEREHA------FGTVGVVARDAT 207
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
G+I AGTST G K GR+GDSPI G+G Y +R +
Sbjct: 208 GEIVAGTSTGGTTAKRWGRVGDSPIIGAGTY-ATPQCGVSATGTGEYFIRLNVAARICTY 266
Query: 181 MRRGSSPTDAAKTAVAR-IASHYPDFMGAVVALKNDGEYGA 220
+ G DA + + + + + D G VV L NDG + A
Sbjct: 267 IESGQDADDALDSVIMQDLTAMGGD--GGVVILANDGPHWA 305
>UniRef50_A3H9E5 Cluster: Peptidase T2, asparaginase 2; n=1;
Caldivirga maquilingensis IC-167|Rep: Peptidase T2,
asparaginase 2 - Caldivirga maquilingensis IC-167
Length = 315
Score = 79.0 bits (186), Expect = 1e-13
Identities = 58/221 (26%), Positives = 97/221 (43%), Gaps = 21/221 (9%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
M IGAV ++ + + I +AR +++ T H + G+ A + A KLW
Sbjct: 88 MRIGAVAAVKNVANPIKLARMIMEKTSHVIIAGDGAAELA----------------KLWK 131
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
+ H + D R+ K +S +L S L + DT+G VA+D+
Sbjct: 132 LYTPTHKLYSDAKSRRYEDMLRDYKS-GKGYFSGNLKLISELGIG----DTVGAVALDKD 186
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
G++AAGTST G K+ GR+GDSPIPG+G + V++R +
Sbjct: 187 GNLAAGTSTGGVWLKLDGRVGDSPIPGAGYWAQNGVAAFSASGLGEVIVRSMVCIRAAYL 246
Query: 181 MRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAA 221
+ G S +A + V + Y + + V+ + G ++
Sbjct: 247 VENGLSIGEALRRVVDDVTKRYGNGLVGVIGIDAKGNVASS 287
>UniRef50_A5URB1 Cluster: Asparaginase; n=2; Roseiflexus|Rep:
Asparaginase - Roseiflexus sp. RS-1
Length = 308
Score = 77.8 bits (183), Expect = 2e-13
Identities = 65/225 (28%), Positives = 104/225 (46%), Gaps = 21/225 (9%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+ GAVG L+ + AISVAR V++ H LVG+ A +FA E+G E+L T ++K+W
Sbjct: 70 LRAGAVGALKGYRAAISVARRVMEDLPHVVLVGDGAARFAAEIGMPRENLLTEHAEKVW- 128
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNH--DTIGMVAID 118
+ ++ P E LLK+S H T+ +A D
Sbjct: 129 ----RAGLEGRTLIDWQGAP----------ELLAALLKRSAALTQDPEHVTGTVNFIAQD 174
Query: 119 QHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTV 178
+ G IA+ ST+G +K PGR+GDSP+ G G Y +R + + V
Sbjct: 175 RQGRIASAVSTSGWAWKYPGRLGDSPMIGGGNYADDRYGAAACTGWGEAAIRAVTARSVV 234
Query: 179 EEMRRGSSPTDAAKTA---VARIASHYPDFMGAVVALKNDGEYGA 220
++ G +A + A +A + P+ M ++VA+ +G + A
Sbjct: 235 LYLKVGYPLEEACREAFRDLAPLLRGTPNTM-SLVAIDRNGNHCA 278
>UniRef50_Q0LJI7 Cluster: Peptidase T2, asparaginase 2; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep: Peptidase T2,
asparaginase 2 - Herpetosiphon aurantiacus ATCC 23779
Length = 300
Score = 76.2 bits (179), Expect = 7e-13
Identities = 43/118 (36%), Positives = 58/118 (49%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVML 169
DT+G VA+D G+IAA TST G K GRIGDSPIPG G Y +
Sbjct: 167 DTVGAVALDGLGNIAAATSTGGMSGKPLGRIGDSPIPGGGFYADSHAGGCSTTGWGETIA 226
Query: 170 RFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINM 227
R L + +E + RG AA+ AVA + G ++ + + G+ GAA + M
Sbjct: 227 RVLLARRAIENLERGMDVQAAAEAAVAVLGQRIEGGEGGLILVASSGQIGAAFNSQRM 284
>UniRef50_A5D1N1 Cluster: Asparaginase; n=1; Pelotomaculum
thermopropionicum SI|Rep: Asparaginase - Pelotomaculum
thermopropionicum SI
Length = 272
Score = 75.4 bits (177), Expect = 1e-12
Identities = 68/243 (27%), Positives = 105/243 (43%), Gaps = 31/243 (12%)
Query: 5 AVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWHN 64
AV +R I++ +SVAR V++ T L G+ A +FA + GF+E + ++ W K
Sbjct: 52 AVAAIRFIRNPVSVARAVMEKTGAVILAGDGALEFARKHGFRESNCISAEQLSTWQK--- 108
Query: 65 EHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGDIA 124
+ N PD G HH DT+G V D +G +A
Sbjct: 109 ---ARENLARGKKPDLNLFTG------LEHHA-------------DTVGCVVWDGNG-LA 145
Query: 125 AGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMRRG 184
A +ST G K+PGR+GD+P G G + + L + E++ G
Sbjct: 146 AASSTGGCSLKMPGRVGDTPCLGGGIF-ASRTSAVVCTGMGEAFIETLTAKYVDEKIESG 204
Query: 185 SSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINMFPYV--VYDKKHSSYQI 242
P AA+ A+ R+ S G ++AL G +G+A + FP + V K Y+
Sbjct: 205 LHPQQAAELALKRLHS-LKGAQGGILALDARGRFGSAFNAA-QFPVIIMVNGKTLEDYEP 262
Query: 243 VNV 245
VN+
Sbjct: 263 VNL 265
>UniRef50_A2E938 Cluster: Family T2, asparaginase-like threonine
peptidase; n=1; Trichomonas vaginalis G3|Rep: Family T2,
asparaginase-like threonine peptidase - Trichomonas
vaginalis G3
Length = 306
Score = 75.4 bits (177), Expect = 1e-12
Identities = 46/126 (36%), Positives = 61/126 (48%), Gaps = 4/126 (3%)
Query: 108 NHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXV 167
+H T+G VA D HG IAAGTST G + GR+GDSP PG G Y
Sbjct: 166 DHGTVGCVARDIHGHIAAGTSTGGTPFAPTGRVGDSPFPGCGVYANDEEGCCSCTGYGEA 225
Query: 168 MLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKND-GEYGAACHGIN 226
+L L T E + + +P AAK A+ A P +G V+ +K + GEYG H
Sbjct: 226 ILVELLGAKTAERLPK-MNPMQAAKEAINAFAKS-PRHVGGVICIKKETGEYG-LYHNTE 282
Query: 227 MFPYVV 232
P+ +
Sbjct: 283 HMPFAM 288
>UniRef50_Q8ZTV2 Cluster: Asparaginase; n=4; Pyrobaculum|Rep:
Asparaginase - Pyrobaculum aerophilum
Length = 299
Score = 73.7 bits (173), Expect = 4e-12
Identities = 58/213 (27%), Positives = 93/213 (43%), Gaps = 26/213 (12%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
GAV + +K A+ +AR+VL++T H + GE A A + G E S K + +
Sbjct: 88 GAVAAVEGVKSAVRLARYVLENTDHVIISGEGARLLAAKTGLLEASY------KFYTEEK 141
Query: 64 NEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGDI 123
N+ + V + R Y++ V F DT+G VA+D+ G++
Sbjct: 142 NKR------FQEVVQEARRGNWHYKR--------------VAEFFGDTVGAVALDRDGNL 181
Query: 124 AAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMRR 183
AA TST G K PGRIGDSPIPG+G + V++ S +E+ +
Sbjct: 182 AAATSTGGVWLKWPGRIGDSPIPGAGFWAENGVGAFSATGVGEVIIMSALSLRARDELIK 241
Query: 184 GSSPTDAAKTAVARIASHYPDFMGAVVALKNDG 216
A + A+ + Y ++ + + G
Sbjct: 242 TGDIGVAVEKAIGFVTESYGPNTAGIIGIDSKG 274
>UniRef50_UPI0000ECCAEA Cluster: asparaginase-like 1 protein; n=6;
Deuterostomia|Rep: asparaginase-like 1 protein - Gallus
gallus
Length = 319
Score = 72.5 bits (170), Expect = 9e-12
Identities = 59/217 (27%), Positives = 95/217 (43%), Gaps = 31/217 (14%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
GAV ++ I + I +AR V++ TKH L A FA MG E ++++ +W
Sbjct: 92 GAVSAVKCIANPIKLARLVMEKTKHMLLTDHGAQLFAQAMGVPEIPGEKLITERSRERWK 151
Query: 64 NEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGDI 123
N+ PD N +QK + T+G VA+D G++
Sbjct: 152 K----------NLEPDS--NPVEFQK------------------DLGTVGAVAVDSEGNV 181
Query: 124 AAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMRR 183
A TST G K+ GR+GD+ GSG Y +++ + + L + M +
Sbjct: 182 ACATSTGGLSNKLVGRVGDTACIGSGGYADNSSGATSTTGHGESIMKVVLARLILYHMEQ 241
Query: 184 GSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGA 220
G SP AA TA+ + + +G V+ + + GE+ A
Sbjct: 242 GMSPEMAADTALEYMKTRVGG-LGGVIVVSSSGEWAA 277
>UniRef50_A7HAG4 Cluster: Asparaginase; n=2; Anaeromyxobacter|Rep:
Asparaginase - Anaeromyxobacter sp. Fw109-5
Length = 310
Score = 72.5 bits (170), Expect = 9e-12
Identities = 60/221 (27%), Positives = 97/221 (43%), Gaps = 26/221 (11%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+ GAV ++ +++ +S+AR +++ + H L G A+ FA E+G V+ +
Sbjct: 95 LRCGAVAVVKDVRNPVSLARAIMERSHHVLLAGPGASAFAREVGILPHDNGLLVTPRQRA 154
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
+W +F SP H L +KS T+G A D
Sbjct: 155 RWEAARAAAGSF----SPRGL------------HPLGEKS---------GTVGAAARDAR 189
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
G +AA TST G + K+PGR+GD+P+ G G Y +++ + E
Sbjct: 190 GHLAAATSTGGMQLKLPGRVGDTPLIGCGTYADDALAAVSCTGHGERIIQLTLARHVAEL 249
Query: 181 MRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAA 221
+ RG + T+AA+ AVA + S G V+ + GE G A
Sbjct: 250 VGRGVAATEAAREAVAALGSRVQG-EGGVIVVGPRGEPGFA 289
>UniRef50_P30364 Cluster: L-asparaginase precursor (EC 3.5.1.1)
(L-asparagine amidohydrolase) [Contains: L-asparaginase
subunit alpha; L-asparaginase subunit beta]; n=21;
Magnoliophyta|Rep: L-asparaginase precursor (EC 3.5.1.1)
(L-asparagine amidohydrolase) [Contains: L-asparaginase
subunit alpha; L-asparaginase subunit beta] - Lupinus
angustifolius (Narrow-leaved blue lupin)
Length = 325
Score = 71.7 bits (168), Expect = 2e-11
Identities = 49/155 (31%), Positives = 76/155 (49%), Gaps = 16/155 (10%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
M GAV GL + + IS+AR V+D T H +L + A FA + G + +V ++
Sbjct: 91 MKCGAVSGLSTVLNPISLARLVMDKTPHIYLAFQGAQDFAKQQGVE------TVDSSHFI 144
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHD----TIGMVA 116
N L ++ + R Y ++ Y + + N D T+G VA
Sbjct: 145 TAENVER------LKLAIEANRVQVDYSQYNYPQPAQDDAEKELPLANGDSQIGTVGCVA 198
Query: 117 IDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
+D HG++A+ TST G K+ GRIGD+P+ G+G Y
Sbjct: 199 VDSHGNLASATSTGGLVNKMVGRIGDTPLIGAGTY 233
>UniRef50_Q4JBL1 Cluster: Asparaginase; n=4; Sulfolobaceae|Rep:
Asparaginase - Sulfolobus acidocaldarius
Length = 284
Score = 70.9 bits (166), Expect = 3e-11
Identities = 39/118 (33%), Positives = 62/118 (52%), Gaps = 1/118 (0%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVML 169
DT+G VA+D+ G++ AGTST G K+PGR+GDSPIPG+G Y ++L
Sbjct: 149 DTVGAVALDKEGNLVAGTSTGGISGKLPGRVGDSPIPGAGFY-ATERVAVSSTGIGEIIL 207
Query: 170 RFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINM 227
R LP+ + G S D+ ++ + ++ S + ++ L + G A + I M
Sbjct: 208 RTLPAKEVDILVSLGISIDDSIRSVINKVTSIFGKDNIGMIGLDSKGFVSAYYNTIGM 265
>UniRef50_A0IK19 Cluster: Peptidase T2, asparaginase 2; n=7;
Proteobacteria|Rep: Peptidase T2, asparaginase 2 -
Serratia proteamaculans 568
Length = 308
Score = 70.5 bits (165), Expect = 4e-11
Identities = 55/195 (28%), Positives = 83/195 (42%), Gaps = 15/195 (7%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+ GAVG L+ H + VA V++ H LVG A +FA E+G + SK++W
Sbjct: 70 LRTGAVGALQGYLHPVEVAYRVMEDLNHEILVGAGAARFAAEIGALAGDNLIADSKRVW- 128
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
W +S + R+ S++ + DT +A D
Sbjct: 129 -WEKLEQA-------MSAEQRRDWPNIPLAGLSNNATDPERVR------DTTVFLAQDSG 174
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
G ++A TST+G +K PGR+GDSPI GSG+Y + +R S V
Sbjct: 175 GTLSAATSTSGWAWKYPGRLGDSPIIGSGSYADSRYGACACTHTGEMTIRCGTSRAVVLY 234
Query: 181 MRRGSSPTDAAKTAV 195
M+ G + A A+
Sbjct: 235 MKMGMTLDQAVYEAI 249
>UniRef50_Q54WW4 Cluster: Putative asparaginase 2; n=1;
Dictyostelium discoideum AX4|Rep: Putative asparaginase
2 - Dictyostelium discoideum AX4
Length = 346
Score = 70.1 bits (164), Expect = 5e-11
Identities = 65/254 (25%), Positives = 107/254 (42%), Gaps = 11/254 (4%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+ GAVGG+ I++ I AR V++HT H LVG+ A +FA + + ++ +
Sbjct: 93 LKAGAVGGVSIIRNPIIAARAVMEHTNHCLLVGKGAEEFAKSKNLEIVEPSFFFTQNRYD 152
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVD----RFNHDTIGMVA 116
+ + + + +K+ + + VD ++ T+G V
Sbjct: 153 QLLRAKDEKKLILDHDGENLLEKEKEKEKNNETSTTTTTISVGVDPIDPKYKMGTVGAVC 212
Query: 117 IDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFL 176
+D G++AA TST G K+ GR+GD+PI G+G Y M R + +F
Sbjct: 213 LDSFGNLAAATSTGGMTNKMHGRVGDTPIIGAGVYANKNVAVSSTGTGEAFM-RTVAAFD 271
Query: 177 TVEEMRRGS-SPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINMF-PYVVYD 234
M GS S DA+ V D G V+ + G + M+ YV+ D
Sbjct: 272 IAAMMEYGSLSLKDASNKVVMEKLITVGD--GGVICVDKYGNVEMPFNTEGMYRGYVIID 329
Query: 235 K--KHSSYQIVNVS 246
++ I+NVS
Sbjct: 330 NNCENDQNDIINVS 343
>UniRef50_Q7UGC2 Cluster: L-asparaginase; n=1; Pirellula sp.|Rep:
L-asparaginase - Rhodopirellula baltica
Length = 471
Score = 68.5 bits (160), Expect = 1e-10
Identities = 35/113 (30%), Positives = 57/113 (50%), Gaps = 2/113 (1%)
Query: 105 DRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXX 164
D + T+G V +D HG++AAGTST G K+PGR+GDSPI G+G Y
Sbjct: 192 DESHLGTVGCVVLDSHGNLAAGTSTGGTANKLPGRVGDSPIVGAGTYAANGLCAVSGTGV 251
Query: 165 XXVMLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGE 217
+R ++ +MR + ++A T + + + +G ++A+ GE
Sbjct: 252 GEEYIRNSVAYDIAAQMRYANQSLESAVTDI--MLNRLDPGVGGLIAVSQQGE 302
Score = 42.7 bits (96), Expect = 0.008
Identities = 20/37 (54%), Positives = 26/37 (70%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFA 40
GAV G+ R+K+ IS+AR V+ TKH LVG A +FA
Sbjct: 123 GAVAGVTRVKNPISLARRVMTETKHVLLVGPGADEFA 159
>UniRef50_Q4HJQ2 Cluster: Asparaginase family protein; n=5;
Campylobacter|Rep: Asparaginase family protein -
Campylobacter lari RM2100
Length = 344
Score = 68.1 bits (159), Expect = 2e-10
Identities = 58/223 (26%), Positives = 96/223 (43%), Gaps = 24/223 (10%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+ GA+ R IK+ I AR V++ T H+ + GE A + A + G + V +K +
Sbjct: 117 LKAGAIAMARTIKNPIEAARLVMEKTPHTLIAGEGADKLAKKHGLE------IVGQKYFF 170
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNH-DTIGMVAIDQ 119
H Q K K+HL V + T+G +A+D+
Sbjct: 171 TEHRYKQLQE--------------AKKSKEVLLDSDKAKAHLGVSTEPYLGTVGAIALDK 216
Query: 120 HGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVE 179
+G++AAGTST G K+ GRIGDSPI G+G Y + +R +
Sbjct: 217 NGNLAAGTSTGGTTNKMTGRIGDSPIIGAGNYANNDSVAISCTGTGDIYIRVAAAHEVAS 276
Query: 180 EMR-RGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAA 221
+ + S AA+ + ++A G ++++ +G+ G A
Sbjct: 277 LYKYKKLSVQKAAEETIKQVAK--LGGTGGIISIDKNGKVGYA 317
>UniRef50_Q0HJ56 Cluster: Peptidase T2, asparaginase 2 precursor;
n=19; Bacteria|Rep: Peptidase T2, asparaginase 2
precursor - Shewanella sp. (strain MR-4)
Length = 343
Score = 67.7 bits (158), Expect = 3e-10
Identities = 51/151 (33%), Positives = 75/151 (49%), Gaps = 19/151 (12%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
MN GAV G+R I + I +A V++ ++H L G A +FA+ GF KL
Sbjct: 117 MNAGAVAGVRHIANPIDLALAVMNKSEHVMLSGAGAEEFALTQGF-----------KLVP 165
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
H + + L+ Q E S + ++D + T+G VA+D++
Sbjct: 166 NSHFDSDARYQQLLDARQK-------LQAAEKSDQIAGIEMKDLD-YKFGTVGAVALDKN 217
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
G++AAGTST G K GRIGDSP+ G+G Y
Sbjct: 218 GNLAAGTSTGGMTAKRFGRIGDSPVIGAGTY 248
>UniRef50_A0PCJ8 Cluster: Putative asparaginase; n=1; Streptomyces
clavuligerus|Rep: Putative asparaginase - Streptomyces
clavuligerus
Length = 390
Score = 67.7 bits (158), Expect = 3e-10
Identities = 59/221 (26%), Positives = 88/221 (39%), Gaps = 23/221 (10%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+ GAV G+ +++ + AR VL+ +KH L GE A F G + + ++ W
Sbjct: 161 LKAGAVAGVTSLRNPVEGARLVLEKSKHVLLSGEGADDFGARHGLRTVTQDYYWTQARWD 220
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
+ DP P D + T+G VA+D+
Sbjct: 221 ALLRAKETEAG-------DPAARRAP--------------EALADAQSTGTVGAVALDRR 259
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLR-FLPSFLTVE 179
GD+AA TST G K+PGRIGDSP+ G+G Y V +R S L+
Sbjct: 260 GDLAAATSTGGLTNKLPGRIGDSPLIGAGTYADNRTVAASATGAGEVFIRGAATSTLSHL 319
Query: 180 EMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGA 220
+G AA + + G V+AL G++ A
Sbjct: 320 IEFKGLGVASAAYEVIVKRLPRLGG-QGGVIALDPRGDFDA 359
>UniRef50_Q8CWF3 Cluster: L-asparaginase; n=3; Bifidobacterium|Rep:
L-asparaginase - Bifidobacterium longum
Length = 310
Score = 67.3 bits (157), Expect = 3e-10
Identities = 38/123 (30%), Positives = 59/123 (47%), Gaps = 4/123 (3%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVM 168
H TIG VA D G+IAAGTST G ++ GR+GDSP+PG G +
Sbjct: 179 HGTIGAVARDAEGNIAAGTSTGGITNQMHGRVGDSPLPGCGTFANQSTVAVSCTGIGEAF 238
Query: 169 LRFLPSFLTVEEMR-RGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINM 227
++ + + + +R G + DAA + +A+H+ D G ++ L G G + M
Sbjct: 239 IKVVAAHQVSDRVRFAGENVEDAATATLDEVAAHHGD--GGMIVLPAVGR-GVVAYNSEM 295
Query: 228 FPY 230
+
Sbjct: 296 MNF 298
>UniRef50_Q47V06 Cluster: Asparaginase; n=2;
Gammaproteobacteria|Rep: Asparaginase - Colwellia
psychrerythraea (strain 34H / ATCC BAA-681)
(Vibriopsychroerythus)
Length = 342
Score = 66.5 bits (155), Expect = 6e-10
Identities = 53/194 (27%), Positives = 86/194 (44%), Gaps = 20/194 (10%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
GAV G++ I++ I++AR V+D + H L G A FA G + V K++ H
Sbjct: 117 GAVAGVKHIENPINLARLVMDESVHVMLSGAGAESFAHSQGVK------LVDNKIFDTDH 170
Query: 64 NEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVD-RFNHDTIGMVAIDQHGD 122
Q R +K + + + +H +D + T+G VA+D+ G+
Sbjct: 171 RYKSLQ------------RAKAKMKKAKQQNKDYQAAHFALDTEYKVGTVGAVALDKFGN 218
Query: 123 IAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRF-LPSFLTVEEM 181
+AAGTST G K GRIGDSP+ G+G + +R+ + + +
Sbjct: 219 VAAGTSTGGMTNKRYGRIGDSPVIGAGTFADNASCAVSATGHGEFFIRYNVAADICARVQ 278
Query: 182 RRGSSPTDAAKTAV 195
+G S A K +
Sbjct: 279 YQGKSIDQAGKEVI 292
>UniRef50_Q3SHK2 Cluster: Putative asparaginase; n=1; Thiobacillus
denitrificans ATCC 25259|Rep: Putative asparaginase -
Thiobacillus denitrificans (strain ATCC 25259)
Length = 341
Score = 65.3 bits (152), Expect = 1e-09
Identities = 60/223 (26%), Positives = 97/223 (43%), Gaps = 15/223 (6%)
Query: 3 IGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKW 62
+GAV L+ ++H + AR V D T H LVG+ A +FA ++ +++ + +
Sbjct: 127 LGAVAALQDVRHPVLAARAVAD-TAHWLLVGDGAREFAARCSLTGNHEPSARARERYAEV 185
Query: 63 HNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGD 122
+E FW SPD P ++ +++ L L ++ T+G V D G
Sbjct: 186 VSE---LARFWCE-SPDADL---PLRRF-WNYALPWDEALK--KWGCGTVGAVVRDATGQ 235
Query: 123 IAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMR 182
+A TST GA + GR+GD+PI GSG Y + +R L + +
Sbjct: 236 LAVATSTGGAVPALRGRVGDTPIIGSGFYAGPRAAVAVTGAGEQI-VRTLLANTVYRWIE 294
Query: 183 RGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGI 225
G P DA K +A PD ++A+ G + G+
Sbjct: 295 TGLPPADALKQGLALFP---PDVDIGIIAVSERESAGLSSRGM 334
>UniRef50_Q2S311 Cluster: Asparaginase superfamily; n=1;
Salinibacter ruber DSM 13855|Rep: Asparaginase
superfamily - Salinibacter ruber (strain DSM 13855)
Length = 345
Score = 65.3 bits (152), Expect = 1e-09
Identities = 61/212 (28%), Positives = 91/212 (42%), Gaps = 26/212 (12%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLD--HTKHSFLVGELATQFAVEMGFQEESLTTSVSKKL 58
++ GAV +R++H + VAR +L+ + LVGE A +FA G + T V +
Sbjct: 121 LDYGAVMAAQRLEHPVGVARRLLETGEGRVRMLVGEGAERFADATGTELVPNETLVHPRE 180
Query: 59 WMKWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAID 118
+ H Q + P+R+ P D DT+G V D
Sbjct: 181 RRR-HERIRAQAE-----ANHPSRSFRPG---------------GADPQGRDTVGAVMRD 219
Query: 119 QHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTV 178
G +AA TST G +K PGR+GDSP+PG+G Y + L +
Sbjct: 220 ATGTLAAATSTGGTPFKPPGRVGDSPLPGAGFYADAHVAVSTTGWGEAIAAVGLARSVR- 278
Query: 179 EEMRRGSSPTDAAKTAVARIASHY--PDFMGA 208
E +R G S AA+ +++R+ PD GA
Sbjct: 279 ERVRAGDSAEAAARASLSRMHEQVRAPDGGGA 310
>UniRef50_Q2RYX8 Cluster: Asparaginase; n=3; Bacteria|Rep:
Asparaginase - Salinibacter ruber (strain DSM 13855)
Length = 403
Score = 64.9 bits (151), Expect = 2e-09
Identities = 43/128 (33%), Positives = 58/128 (45%), Gaps = 4/128 (3%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVM 168
+ T+G VA+D G++AAGTST G K GR+GDSPI G+G Y
Sbjct: 264 YGTVGAVALDAAGNLAAGTSTGGISDKEFGRVGDSPIVGAGTYAHNASCAVSATGQGEFF 323
Query: 169 LRFLPSFLTVEEMRRGSSPT-DAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINM 227
+R + + MR G P +AA+ + I +G V+AL DG M
Sbjct: 324 IRGVAAHSVASRMRFGDRPLGEAAQRTIDEIEE--LGGVGGVIALDRDGNIATPFSTGGM 381
Query: 228 F-PYVVYD 234
F YV D
Sbjct: 382 FRAYVAPD 389
Score = 35.1 bits (77), Expect = 1.7
Identities = 15/45 (33%), Positives = 26/45 (57%)
Query: 2 NIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQ 46
N GA+ G++ +KH I +AR +++ + H E A FA + G +
Sbjct: 187 NAGALTGVQTVKHPIRLARAIMEDSYHVMFAQEGAEAFAEQQGLE 231
>UniRef50_Q9VXT7 Cluster: Probable L-asparaginase CG7860; n=3;
Diptera|Rep: Probable L-asparaginase CG7860 - Drosophila
melanogaster (Fruit fly)
Length = 332
Score = 64.9 bits (151), Expect = 2e-09
Identities = 59/222 (26%), Positives = 92/222 (41%), Gaps = 20/222 (9%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMG---FQEESLTTSVSKK 57
+ G + LR + H I+VAR +++ +H+FL G A + A+ G Q +L T +
Sbjct: 92 LRAGCITLLRDVMHPITVARRLMEKQRHTFLGGAAAQELALATGSERLQPGALVTE-GAR 150
Query: 58 LWMKWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAI 117
L +K + Q DP + + E + K D + +T+G VA+
Sbjct: 151 LTLKEFEDQVAQ-------GKDPF-----FARTELTDD---KPVPKTDP-SGETVGAVAM 194
Query: 118 DQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLT 177
D G I GTST G K PGRIGD+PI GSG Y ++R+ +
Sbjct: 195 DASGQIVVGTSTGGITGKWPGRIGDTPILGSGTYADNCRGGVSTTGHGETLMRYNLAQRI 254
Query: 178 VEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYG 219
+ M AA R + G + + + G+ G
Sbjct: 255 LSAMEYQGLSAQAAADKECREMTKRLGGTGGAIVVGHSGDLG 296
>UniRef50_Q4RQ97 Cluster: Chromosome 17 SCAF15006, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 17 SCAF15006, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1023
Score = 62.5 bits (145), Expect = 1e-08
Identities = 30/83 (36%), Positives = 44/83 (53%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVM 168
HDT+G VA+D G++A TST G + K+ GR+GDSPI G G Y +
Sbjct: 188 HDTVGAVAVDSVGNVACATSTGGIRNKMAGRVGDSPIIGCGGYADNLSGAVSCTGHGESI 247
Query: 169 LRFLPSFLTVEEMRRGSSPTDAA 191
L+ + L + M +G ++AA
Sbjct: 248 LKVTLARLILSHMEQGLDGSEAA 270
>UniRef50_Q16RJ1 Cluster: L-asparaginase; n=5; Endopterygota|Rep:
L-asparaginase - Aedes aegypti (Yellowfever mosquito)
Length = 386
Score = 62.5 bits (145), Expect = 1e-08
Identities = 34/114 (29%), Positives = 57/114 (50%), Gaps = 2/114 (1%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLR 170
T+G VAID+ G+IAA TST G K+PGR+GD+PI G+G Y +++
Sbjct: 225 TVGAVAIDKFGNIAAATSTGGLTGKLPGRVGDTPIIGAGTYADNLIGGISATGDGDTIMK 284
Query: 171 FLPSFLTVEEMR-RGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACH 223
+ ++ M G + A++ A+A ++ D ++ L +G C+
Sbjct: 285 VSLVYDILKRMEYLGDDMSKASEDALAAMSERL-DGTAGIIGLDTNGNVAIVCN 337
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 4/66 (6%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVG----ELATQFAVEMGFQEESLTTSVSK 56
+ G V G+R + H I++AR V+D T+H+FL G + + +E+ + L T SK
Sbjct: 146 LKAGCVAGVRDVLHPITLARRVMDKTRHNFLAGLGLVDFTEKEGIEIMYPPGQLVTQFSK 205
Query: 57 KLWMKW 62
KW
Sbjct: 206 DSLDKW 211
>UniRef50_A2BJV5 Cluster: L asparaginase; n=1; Hyperthermus
butylicus DSM 5456|Rep: L asparaginase - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 318
Score = 62.5 bits (145), Expect = 1e-08
Identities = 38/112 (33%), Positives = 52/112 (46%), Gaps = 1/112 (0%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVML 169
DT+G V + G +AAGTST G K PGR+GDSPIPG+G Y ++
Sbjct: 178 DTVGAVVLVS-GRLAAGTSTGGIALKHPGRVGDSPIPGAGFYVEHGVGGCAATGIGETII 236
Query: 170 RFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAA 221
P V+ + G +AA+ AVAR + ++ L G AA
Sbjct: 237 LSRPCIHAVKLLAEGMPVEEAARAAVARHTRLFGSDNLGIILLDAKGNAAAA 288
>UniRef50_Q62CC7 Cluster: Asparaginase family protein; n=30;
cellular organisms|Rep: Asparaginase family protein -
Burkholderia mallei (Pseudomonas mallei)
Length = 356
Score = 62.1 bits (144), Expect = 1e-08
Identities = 35/95 (36%), Positives = 49/95 (51%), Gaps = 2/95 (2%)
Query: 102 LNVDRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXX 161
L+ DR H T+G VA D HG +AA TST G K PGR+GD+PI G+G Y
Sbjct: 211 LDPDR-KHGTVGAVARDLHGHLAAATSTGGITNKQPGRVGDTPIIGAGCYANDATCAVSA 269
Query: 162 XXXXXVMLRFLPSF-LTVEEMRRGSSPTDAAKTAV 195
+ +R ++ ++ + RG+S AA V
Sbjct: 270 TGTGEMFIRLATAYDVSAQIEYRGASLAGAAYDVV 304
>UniRef50_Q1VJC1 Cluster: Probable l-asparaginase protein; n=1;
Psychroflexus torquis ATCC 700755|Rep: Probable
l-asparaginase protein - Psychroflexus torquis ATCC
700755
Length = 257
Score = 62.1 bits (144), Expect = 1e-08
Identities = 44/151 (29%), Positives = 67/151 (44%), Gaps = 24/151 (15%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEES---LTTSVSKKLWM 60
G+V GL+ +H + A ++++ L G FA E G ++ L T + + W
Sbjct: 34 GSVVGLQSSRHPVRAAERLMENGWPVMLAGPAGDVFAAENGVEQVEKAWLETQLRRAQWD 93
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQH 120
KW E + P T H+ H T+G VA+D +
Sbjct: 94 KWRRER---------LRPGATDEEDALLDHDAEHD------------GWGTVGAVALDAN 132
Query: 121 GDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
G++AA TST G K PGR+GD+PI G+G +
Sbjct: 133 GNLAAATSTGGMTGKPPGRVGDTPIIGAGTW 163
>UniRef50_A3DPP6 Cluster: Peptidase T2, asparaginase 2; n=1;
Staphylothermus marinus F1|Rep: Peptidase T2,
asparaginase 2 - Staphylothermus marinus (strain ATCC
43588 / DSM 3639 / F1)
Length = 319
Score = 62.1 bits (144), Expect = 1e-08
Identities = 36/111 (32%), Positives = 54/111 (48%), Gaps = 3/111 (2%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVML 169
DT+G VA+D +G +A ST G K+PGRIGDSPIPG+G Y +++
Sbjct: 186 DTVGAVAVDDNGLLATAVSTGGVILKLPGRIGDSPIPGAGFY-SSRKVACSATGFGEMII 244
Query: 170 RFLPSFLTVEEMRRGSSPTDAAKTAVARIASHY-PDFMGAVVALKNDGEYG 219
R +P E + +G +A + + D MG +A+ +G G
Sbjct: 245 RSMPCLKLAEYIDQGMDFEEALDNVITYVNETVGKDTMG-FIAVDYEGRIG 294
>UniRef50_A7RM62 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 380
Score = 61.7 bits (143), Expect = 2e-08
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 1/111 (0%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLR 170
T+G VA+D G++A TST G PGR+GDSPI G G Y +++R
Sbjct: 183 TVGAVAVDSFGNVACATSTGGLTAVHPGRVGDSPIVGCGGYADNQVAAASSTGTGEMIMR 242
Query: 171 FLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAA 221
+ + ++ G + DAA A+ + G ++ + DGE G A
Sbjct: 243 VNLARYALFMIQIGQTAADAAAAALRYMEQRVGGRAG-IIIVSRDGEAGIA 292
Score = 46.4 bits (105), Expect = 7e-04
Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 3/60 (5%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQE---ESLTTSVSKK 57
+N+G VGG+ + + ISVAR V+ + H L+GE A FA E G E+L T ++
Sbjct: 98 LNVGGVGGISGVSNPISVARKVMTESNHCLLIGEGANMFADEQGIPRIPPEALITEARRR 157
>UniRef50_A6BYT5 Cluster: Putative asparaginase; n=1; Planctomyces
maris DSM 8797|Rep: Putative asparaginase - Planctomyces
maris DSM 8797
Length = 263
Score = 61.3 bits (142), Expect = 2e-08
Identities = 56/219 (25%), Positives = 95/219 (43%), Gaps = 21/219 (9%)
Query: 2 NIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMK 61
+ AV + R+K+ ++VAR +L+ T H LVG+ AT +A + G+++ TT+ +K K
Sbjct: 51 DFAAVAAIERVKNPVAVARCLLE-TPHILLVGDGATTYARQCGYEDYDPTTAGAKSRLQK 109
Query: 62 WHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHG 121
L+VS G + + + ++ + DT+G VA D
Sbjct: 110 I-----------LSVS----EQMGDWSRADLERAWNFETPFR-EALGTDTVGSVAWDGQ- 152
Query: 122 DIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEM 181
A+ S+ G + GR+GD P+PG G Y + R L ++ E+
Sbjct: 153 TFASALSSGGTTIVLRGRVGDVPLPGCGLYASKAGAIATTGDGEYI-ARSLLAYRAYLEL 211
Query: 182 RRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGA 220
+G SP A+ +A +G +V + D GA
Sbjct: 212 EKGLSPAQTVDWALNELADSVD--IGIIVVNQTDFAGGA 248
>UniRef50_A7SD31 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 291
Score = 60.9 bits (141), Expect = 3e-08
Identities = 38/120 (31%), Positives = 60/120 (50%), Gaps = 10/120 (8%)
Query: 126 GTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEMRRGS 185
G S++G +K PGR+GDSP+PGSG + +LRF PS+ V+ M +G
Sbjct: 170 GVSSSGKPFKSPGRVGDSPLPGSGLF----ADNEVSSGDGDFLLRFCPSYQAVQLMSQGY 225
Query: 186 SPTDAAKTAV----ARIASHYPDFMGAVVALKNDGEYGAACHGINMFPYVVYDKKHSSYQ 241
+P +A + V + + F AV+A+ G GAA FPY V+ ++ + +
Sbjct: 226 TPQEACEQVVRVSQTKAGTLSEPFEMAVLAIDKVGRVGAA--STVEFPYTVWRQQDDTLE 283
Score = 40.7 bits (91), Expect = 0.033
Identities = 26/56 (46%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQ---EESLTTSVSK 56
GAV L+ + SVAR VL+ + HS LVG A FA + G + EESL T SK
Sbjct: 77 GAVAALQGVATPFSVARLVLERSPHSMLVGSGAHTFAEQNGVKIESEESLQTQESK 132
>UniRef50_Q9AAM1 Cluster: Asparaginase family protein; n=6;
Alphaproteobacteria|Rep: Asparaginase family protein -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 294
Score = 60.1 bits (139), Expect = 5e-08
Identities = 35/108 (32%), Positives = 51/108 (47%), Gaps = 2/108 (1%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVM 168
H T+G VA+D+ G +AA TST G K PGR+GD+P+PG+G + +
Sbjct: 163 HGTVGAVALDRRGALAAATSTGGVFGKRPGRVGDTPLPGAGVWADGEVAVSCTGVGEYFI 222
Query: 169 LRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDG 216
L + G S A + A+ARI D G ++A+ G
Sbjct: 223 LGATAYDVAARLRYAGQSLDQACQGAIARIGELGGD--GGLIAVDRRG 268
Score = 33.9 bits (74), Expect = 3.8
Identities = 17/41 (41%), Positives = 23/41 (56%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMG 44
GAV ++ + + AR VL+ T H L GE A+QFA G
Sbjct: 92 GAVCAIQGVASPVGAARQVLEATPHVLLAGEGASQFARARG 132
>UniRef50_A0VHR1 Cluster: Peptidase T2, asparaginase 2; n=6;
Proteobacteria|Rep: Peptidase T2, asparaginase 2 -
Delftia acidovorans SPH-1
Length = 462
Score = 59.7 bits (138), Expect = 7e-08
Identities = 42/126 (33%), Positives = 56/126 (44%), Gaps = 3/126 (2%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLR 170
T+G VA D HG++AA ST G K PGR+GD+P+ G+G Y LR
Sbjct: 329 TVGAVARDVHGNLAAAASTGGLTNKRPGRVGDTPVVGAGFYADSTTCAVAATGTGEHFLR 388
Query: 171 FLPSFLTVEEMR-RGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINMF- 228
+ MR G S AA AV +H G VVA+ + G + M+
Sbjct: 389 AAIAHDIHARMRYLGQSLELAADAAVRGTLTHIGG-QGGVVAVDSQGRVHCPFNSAGMYR 447
Query: 229 PYVVYD 234
Y+V D
Sbjct: 448 GYIVDD 453
Score = 39.1 bits (87), Expect = 0.10
Identities = 19/44 (43%), Positives = 29/44 (65%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMG 44
+ GAV + ++++ I++ARHVLD + LVGE A +FA E G
Sbjct: 233 LRAGAVASVSQVRNPIALARHVLDDGQCVLLVGEGAQRFADERG 276
>UniRef50_A7SKS4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 227
Score = 59.7 bits (138), Expect = 7e-08
Identities = 50/161 (31%), Positives = 78/161 (48%), Gaps = 23/161 (14%)
Query: 1 MNIGAVGGLRRIKHAISVARHVL-DHTKHS---------FLVGELATQFAVEMGFQEESL 50
M GAVG +RR+K+ VA H+L D K FLVGE A +A + G +
Sbjct: 54 MGFGAVGAIRRVKNPSQVAHHILRDEIKGPKTLGLVPPVFLVGEGAECWARDYGIPGVTE 113
Query: 51 TTSVSKKLWMKWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHD 110
+ +++K +H LN S P+ P ++ +L+ S L D
Sbjct: 114 QSLITEKSLASYHRYKE-----RLN-STKPSELHQPKKQKLDDMDVLEDSSL-------D 160
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
T+G+V +D G ++AG+S+ G K PGR+G + + G+G Y
Sbjct: 161 TVGVVCVDTAGCVSAGSSSGGLLLKKPGRVGQAAVYGAGCY 201
>UniRef50_P50287 Cluster: L-asparaginase 1 precursor (EC 3.5.1.1)
(L-asparagine amidohydrolase 1) [Contains:
L-asparaginase 1 subunit alpha; L-asparaginase 1 subunit
beta]; n=7; Magnoliophyta|Rep: L-asparaginase 1
precursor (EC 3.5.1.1) (L-asparagine amidohydrolase 1)
[Contains: L-asparaginase 1 subunit alpha;
L-asparaginase 1 subunit beta] - Arabidopsis thaliana
(Mouse-ear cress)
Length = 315
Score = 58.0 bits (134), Expect = 2e-07
Identities = 46/150 (30%), Positives = 70/150 (46%), Gaps = 22/150 (14%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKK--LWMK 61
GAV GL + + IS+AR V++ T H +L + A FA G + + ++ + +K
Sbjct: 94 GAVSGLTTVVNPISLARLVMEKTPHIYLAFDAAEAFARAHGVETVDSSHFITPENIARLK 153
Query: 62 WHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHG 121
E + + SP NCG Q T+G VA+D G
Sbjct: 154 QAKEFNRVQLDYTVPSPKVPDNCGDSQI--------------------GTVGCVAVDSAG 193
Query: 122 DIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
++A+ TST G K+ GRIGD+P+ G+G Y
Sbjct: 194 NLASATSTGGYVNKMVGRIGDTPVIGAGTY 223
>UniRef50_A0RU73 Cluster: L-asparaginase; n=2; Cenarchaeum
symbiosum|Rep: L-asparaginase - Cenarchaeum symbiosum
Length = 279
Score = 57.6 bits (133), Expect = 3e-07
Identities = 36/133 (27%), Positives = 59/133 (44%), Gaps = 1/133 (0%)
Query: 103 NVDRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXX 162
N+D T+G +D HGD+AA ST G GR+G S I GSG Y
Sbjct: 140 NMDHEKLGTVGAAILDTHGDMAAAVSTGGTGTMPSGRVGASAIAGSGYYAKNGAGAAATT 199
Query: 163 XXXXVMLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAAC 222
+L + E M + S+ A+ +V + + P MG ++++ +GE G +
Sbjct: 200 GNGDTLLMSGTARRCCELMEKKSAAQAASDLSVKELGA-LPGGMGGIISVDANGEIGFSF 258
Query: 223 HGINMFPYVVYDK 235
+ +M + D+
Sbjct: 259 NTTSMTYACINDR 271
Score = 34.7 bits (76), Expect = 2.2
Identities = 15/47 (31%), Positives = 28/47 (59%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESL 50
G VG + +K+ ++VA V+ + HS +VG A FA+ G ++ ++
Sbjct: 89 GGVGAISDVKNPVAVASKVMSLSDHSVIVGPGALSFALSHGMEKYTM 135
>UniRef50_UPI000155F543 Cluster: PREDICTED: similar to ASRGL1
protein; n=2; Equus caballus|Rep: PREDICTED: similar to
ASRGL1 protein - Equus caballus
Length = 440
Score = 56.8 bits (131), Expect = 5e-07
Identities = 38/140 (27%), Positives = 64/140 (45%), Gaps = 2/140 (1%)
Query: 108 NHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXV 167
N T+G VA+D G++A TST G K+ GR+GD+P GSG Y
Sbjct: 297 NLGTVGAVALDCRGNVAYATSTGGIVNKMVGRVGDTPCIGSGGYADNDIGAVSTTGHGES 356
Query: 168 MLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINM 227
+++ + L + M +G + +AA ++ + S +G V+ + G++ +M
Sbjct: 357 IMKVNLARLALFHMEQGKTLEEAADISLGYMKSKLKG-LGGVILVSKAGDWAVKWTSASM 415
Query: 228 FPYVVYD-KKHSSYQIVNVS 246
V D K HS + + S
Sbjct: 416 PWAAVKDGKLHSGIYLDDTS 435
Score = 41.1 bits (92), Expect = 0.025
Identities = 25/72 (34%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQE---ESLTTSVSKK 57
++ GAV +R + + I +AR V++ T H FL + A +FA MG E + L T + K
Sbjct: 219 LSAGAVSAVRCVANPIKLARLVMEKTPHCFLTDQGAAKFAAAMGIPEVPGKQLVTERNIK 278
Query: 58 LWMKWHNEHHCQ 69
L K +E Q
Sbjct: 279 LLAKEKHEKDAQ 290
>UniRef50_A4BV37 Cluster: Putative L-asparaginase; n=1; Nitrococcus
mobilis Nb-231|Rep: Putative L-asparaginase -
Nitrococcus mobilis Nb-231
Length = 303
Score = 56.8 bits (131), Expect = 5e-07
Identities = 33/92 (35%), Positives = 46/92 (50%), Gaps = 1/92 (1%)
Query: 105 DRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXX 164
D + T+G VA D G++AA TST G K K PGR+GDSP+ G+G Y
Sbjct: 155 DEHGYGTVGAVARDCAGNLAAATSTGGQKGKRPGRVGDSPLVGAGTYADNEGCAVSCTGW 214
Query: 165 XXVMLR-FLPSFLTVEEMRRGSSPTDAAKTAV 195
+R L ++L +R G AA+ A+
Sbjct: 215 GEDFIRTALAAYLDFLIVREGLEAHTAARIAI 246
Score = 33.5 bits (73), Expect = 5.1
Identities = 15/44 (34%), Positives = 24/44 (54%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMG 44
+ GAV + RI++ + +AR +++ T H L G A FA G
Sbjct: 92 LEAGAVTYVERIRNPVELARRIMEQTPHVMLAGRGAGDFAATNG 135
>UniRef50_Q7L266 Cluster: L-asparaginase; n=17; Euteleostomi|Rep:
L-asparaginase - Homo sapiens (Human)
Length = 308
Score = 56.8 bits (131), Expect = 5e-07
Identities = 32/106 (30%), Positives = 51/106 (48%)
Query: 108 NHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXV 167
N T+G VA+D G++A TST G K+ GR+GDSP G+G Y
Sbjct: 165 NLGTVGAVALDCKGNVAYATSTGGIVNKMVGRVGDSPCLGAGGYADNDIGAVSTTGHGES 224
Query: 168 MLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALK 213
+L+ + LT+ + +G + +AA ++ + S G +V K
Sbjct: 225 ILKVNLARLTLFHIEQGKTVEEAADLSLGYMKSRVKGLGGLIVVSK 270
Score = 42.7 bits (96), Expect = 0.008
Identities = 27/72 (37%), Positives = 38/72 (52%), Gaps = 3/72 (4%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQE---ESLTTSVSKK 57
++ GAV ++ I + I +AR V++ T H FL + A QFA MG E E L T +KK
Sbjct: 87 LSAGAVSAVQCIANPIKLARLVMEKTPHCFLTDQGAAQFAAAMGVPEIPGEKLVTERNKK 146
Query: 58 LWMKWHNEHHCQ 69
K +E Q
Sbjct: 147 RLEKEKHEKGAQ 158
>UniRef50_A6WWK5 Cluster: Peptidase T2 asparaginase 2; n=1;
Ochrobactrum anthropi ATCC 49188|Rep: Peptidase T2
asparaginase 2 - Ochrobactrum anthropi (strain ATCC
49188 / DSM 6882 / NCTC 12168)
Length = 311
Score = 56.4 bits (130), Expect = 6e-07
Identities = 23/43 (53%), Positives = 31/43 (72%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
H T+G VA+D+ G +AA TST G K PGR+GDSP+ G+G +
Sbjct: 176 HGTVGAVALDRFGHLAAATSTGGMTAKTPGRVGDSPVIGAGTW 218
>UniRef50_A5BIQ7 Cluster: Putative uncharacterized protein; n=2;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 160
Score = 56.4 bits (130), Expect = 6e-07
Identities = 29/72 (40%), Positives = 39/72 (54%), Gaps = 1/72 (1%)
Query: 174 SFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINMFPYVVY 233
S+ VE MR G P AA+ A+ RIA +PDF+GAV A +G + ACHG F Y V
Sbjct: 88 SYQVVESMRLGMEPKLAAQDAIKRIARKFPDFVGAVFAFNKNGLHAGACHGWT-FQYSVR 146
Query: 234 DKKHSSYQIVNV 245
+ ++ V
Sbjct: 147 SPEMEDVEVFTV 158
>UniRef50_Q6L1Z2 Cluster: Asparaginase; n=4; Thermoplasmatales|Rep:
Asparaginase - Picrophilus torridus
Length = 297
Score = 56.4 bits (130), Expect = 6e-07
Identities = 43/148 (29%), Positives = 75/148 (50%), Gaps = 23/148 (15%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
G+V + +K+ + VAR V++ + H + G+ A +FA +GF++ +T + K
Sbjct: 99 GSVMAIENVKNPVLVARAVMERSPHLIMAGDGAEKFAHLLGFEKYDPSTERAAK-----R 153
Query: 64 NEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGDI 123
E+ ++S +R Y K +++ +F DT+G VA +G+
Sbjct: 154 REN--------DISMILSRKIDSYNK--------MMETVDISKFV-DTVGAVA-RVNGEF 195
Query: 124 AAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
AA ST GA + GR+GDSP+PG+G +
Sbjct: 196 AAAVSTGGAPPMLRGRVGDSPVPGAGIF 223
>UniRef50_A7D1A3 Cluster: Asparaginase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Asparaginase - Halorubrum
lacusprofundi ATCC 49239
Length = 350
Score = 56.4 bits (130), Expect = 6e-07
Identities = 64/235 (27%), Positives = 98/235 (41%), Gaps = 13/235 (5%)
Query: 3 IGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKW 62
IGA + ++HA SVAR V T H F+ G+ A A E F E+ ++ + ++
Sbjct: 124 IGAACSMPGVEHAASVARVVHSETPHIFISGDHAVDLASE--FDIETGVDLLTDETRERY 181
Query: 63 HNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRF-NHDTIGMVAIDQHG 121
E Q ++ TR + ++S + R +HDT+G VA D
Sbjct: 182 EAEDPPQGGPREHLDWLATRFGSGDDQAGGGSGSDEESEDDAGRAPDHDTVGAVATDGE- 240
Query: 122 DIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEEM 181
AA TST G + + GR+GD P GSG + + R S V+ +
Sbjct: 241 TFAAATSTGGRSFALAGRVGDVPQVGSGFFCTEAGGASATGAGEDI-ARVTLSRRAVDFL 299
Query: 182 RRGSSPTDAAKTAVARIASHYPDFMGA---VVALKNDGEYGAACHGINMFPYVVY 233
G DAA A+ + D G+ V+ L +DG G+A + M + Y
Sbjct: 300 DDGFGAQDAADRAI----DEFEDITGSGAGVIVLGDDGA-GSAFNTDGMQTSIAY 349
>UniRef50_UPI0000DB78D0 Cluster: PREDICTED: similar to
asparaginase-like sperm autoantigen; n=1; Apis
mellifera|Rep: PREDICTED: similar to asparaginase-like
sperm autoantigen - Apis mellifera
Length = 920
Score = 56.0 bits (129), Expect = 8e-07
Identities = 39/138 (28%), Positives = 64/138 (46%), Gaps = 4/138 (2%)
Query: 108 NHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXV 167
N T+G VA D + +AAGT+T G K+ GR+GDSP+ G G Y +
Sbjct: 596 NTGTVGCVAYDGYS-VAAGTTTGGLNKKLVGRVGDSPLLGCGTYAIRNIGCSLTGHGESI 654
Query: 168 MLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINM 227
L + VE++ + S +A ++ + Y G +V L+++G + A +
Sbjct: 655 TKLGLARAI-VEDIEQNFSHMEALYKNLSHMLEKYKKVGGGIV-LQSNGHW-ATYFTSDK 711
Query: 228 FPYVVYDKKHSSYQIVNV 245
PY V D +Y V++
Sbjct: 712 MPYAVIDNDLITYGTVDI 729
>UniRef50_A3WE63 Cluster: Asparaginase family protein; n=3;
Erythrobacter|Rep: Asparaginase family protein -
Erythrobacter sp. NAP1
Length = 404
Score = 56.0 bits (129), Expect = 8e-07
Identities = 28/52 (53%), Positives = 36/52 (69%), Gaps = 1/52 (1%)
Query: 100 SHLNVDRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
S L+VD T+G VA+DQ G++AAGTST G K GRIGD+P+ G+G Y
Sbjct: 213 SALDVDH-KFGTVGAVALDQDGNLAAGTSTGGMTGKRWGRIGDAPVVGAGTY 263
Score = 38.7 bits (86), Expect = 0.14
Identities = 19/42 (45%), Positives = 27/42 (64%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGF 45
GAV G+ +++ I +A V + H FL+GE A QFA+E GF
Sbjct: 146 GAVTGVTTVRNPILLADRVRTDSPHVFLMGEGAEQFALERGF 187
>UniRef50_A3EVA9 Cluster: Asparaginase; n=1; Leptospirillum sp.
Group II UBA|Rep: Asparaginase - Leptospirillum sp.
Group II UBA
Length = 313
Score = 54.8 bits (126), Expect = 2e-06
Identities = 25/47 (53%), Positives = 33/47 (70%)
Query: 105 DRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
D+ +H T+G VA D++G +AA TST GA GRIGDS +PG+G Y
Sbjct: 151 DQGDHGTVGAVARDRNGHLAATTSTGGAGRMRAGRIGDSAVPGAGTY 197
>UniRef50_Q6A5Z2 Cluster: Putative asparaginase; n=1;
Propionibacterium acnes|Rep: Putative asparaginase -
Propionibacterium acnes
Length = 321
Score = 54.0 bits (124), Expect = 3e-06
Identities = 35/121 (28%), Positives = 50/121 (41%), Gaps = 8/121 (6%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVM 168
H T+G VA D++G +AA TST G GRIGDSP+ G+G +
Sbjct: 184 HGTVGAVARDRYGHLAAATSTGGIVASSQGRIGDSPVIGAGTFARDGVVAVSCTGDGEAF 243
Query: 169 LRFLPSFLTVEEMRRGSSPTDAAKTAV------ARIASHYPDFMGAVVALKNDGEYGAAC 222
L+ + + +MR P D A +R+ H P G + + E C
Sbjct: 244 LQGVVAHEVDAQMRLAGQPVDRAALGALTDEVSSRLTGHAPATDGLIAV--DSCEQLVVC 301
Query: 223 H 223
H
Sbjct: 302 H 302
>UniRef50_Q7CRG0 Cluster: AGR_L_3520p; n=2; Agrobacterium
tumefaciens str. C58|Rep: AGR_L_3520p - Agrobacterium
tumefaciens (strain C58 / ATCC 33970)
Length = 330
Score = 53.6 bits (123), Expect = 4e-06
Identities = 37/121 (30%), Positives = 51/121 (42%), Gaps = 2/121 (1%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVM 168
H T+G VA+D G +AA TST G K GR+GDSP+ G+G Y
Sbjct: 188 HGTVGAVALDAAGHLAAATSTGGYTNKPDGRVGDSPVIGAGTYARDGACAVSGTGKGEFF 247
Query: 169 LRFLPSFLTVEEMR-RGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINM 227
+R++ + G AA V R + Y D +VA+ G A + M
Sbjct: 248 IRYVVGHEIASRVAYLGQDLETAAGNLVHRDLAPY-DIGAGLVAIDAKGGITAPYNTPGM 306
Query: 228 F 228
F
Sbjct: 307 F 307
Score = 33.9 bits (74), Expect = 3.8
Identities = 16/57 (28%), Positives = 30/57 (52%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKK 57
++ GA+ R I++ + AR ++ + +L GE A +FA E G E + ++K
Sbjct: 108 LSAGAISASRAIRNPVKAARALMVDERAVYLTGEAADRFATEKGLATEPQSYFTTQK 164
>UniRef50_Q9H6P5 Cluster: Threonine aspartase 1 (EC 3.4.25.-)
(Taspase-1) [Contains: Threonine aspartase subunit
alpha; Threonine aspartase subunit beta]; n=24;
Euteleostomi|Rep: Threonine aspartase 1 (EC 3.4.25.-)
(Taspase-1) [Contains: Threonine aspartase subunit
alpha; Threonine aspartase subunit beta] - Homo sapiens
(Human)
Length = 420
Score = 53.6 bits (123), Expect = 4e-06
Identities = 46/161 (28%), Positives = 67/161 (41%), Gaps = 21/161 (13%)
Query: 1 MNIGAVGGLRRIKHAISVARHVL-DHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLW 59
+N GAVG L IK+ +SVA +L + K G + F V G W
Sbjct: 125 LNFGAVGALSGIKNPVSVANRLLCEGQKGKLSAGRIPPCFLVGEGAYR-----------W 173
Query: 60 MKWHNEHHCQPN-----FWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNH----D 110
H C PN F L R ++ + LKK + ++ N D
Sbjct: 174 AVDHGIPSCPPNIMTTRFSLAAFKRNKRKLELAERVDTDFMQLKKRRQSSEKENDSGTLD 233
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
T+G V +D G++AA S+ G K PGR+G + + G G +
Sbjct: 234 TVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCW 274
>UniRef50_A1ZI34 Cluster: Asparaginase; n=1; Microscilla marina ATCC
23134|Rep: Asparaginase - Microscilla marina ATCC 23134
Length = 317
Score = 52.8 bits (121), Expect = 8e-06
Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 4/134 (2%)
Query: 97 LKKSHLNVDRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXX 156
L S N +F T+G VA+D++G++AA TST G K GRIGDS I G+G Y
Sbjct: 164 LDHSKDNAKKFG--TVGAVALDKNGNVAAATSTGGMTNKKYGRIGDSSIIGAGTYANNAT 221
Query: 157 XXXXXXXXXXVMLRFLPSF-LTVEEMRRGSSPTDAAKTAV-ARIASHYPDFMGAVVALKN 214
LR + ++ ++ +G S +A+ + ++ + G ++A+
Sbjct: 222 CAVSCTGHGEPFLRAVSAYDISCLMEYKGLSLEEASNYLIHEKMKQTHLQGEGGLIAIDT 281
Query: 215 DGEYGAACHGINMF 228
G A + + M+
Sbjct: 282 TGNISIAFNTVGMY 295
>UniRef50_Q0E667 Cluster: L-asparaginase; n=3; Spermatophyta|Rep:
L-asparaginase - Pinus sylvestris (Scots pine)
Length = 375
Score = 52.8 bits (121), Expect = 8e-06
Identities = 31/125 (24%), Positives = 56/125 (44%), Gaps = 3/125 (2%)
Query: 104 VDRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXX 163
++ + +T+G V +D G A+ TST G K+ GRIGDSPI G+G Y
Sbjct: 238 INIYEPETVGCVVVDSEGHCASATSTGGLINKMSGRIGDSPIIGAGTYANGLCAVSATGE 297
Query: 164 XXXVMLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACH 223
++ + + +G S ++ + + D G ++A+ ++G+ A +
Sbjct: 298 GEAIIRATVGRDVAALMEYKGLSLQESVDFVINK---RLEDGKGGLIAVSSNGDVAAGFN 354
Query: 224 GINMF 228
MF
Sbjct: 355 TSGMF 359
Score = 35.1 bits (77), Expect = 1.7
Identities = 17/43 (39%), Positives = 26/43 (60%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQ 46
GAV GL +K+ IS+AR V++ + H +L A +FA G +
Sbjct: 92 GAVSGLSTVKNPISLARLVMERSPHVYLAFNGAEEFARAQGVE 134
>UniRef50_Q1E8D8 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 457
Score = 52.8 bits (121), Expect = 8e-06
Identities = 36/98 (36%), Positives = 44/98 (44%), Gaps = 4/98 (4%)
Query: 56 KKLWMKWHNEHHCQPNFWLNVSPDPTRNC--GPYQKHEYSH--HLLKKSHLNVDRFNHDT 111
+KL W E FW D R GP + H + SH + T
Sbjct: 209 EKLASDWGLEFKPDEWFWTKRRWDEHRRGLQGPKVEATIDHDAEMDLTSHDGDKYLSQGT 268
Query: 112 IGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
+G V IDQ G+IA TST G K PGRIGD+P G+G
Sbjct: 269 VGAVCIDQWGNIAVATSTGGLTNKFPGRIGDTPTLGAG 306
>UniRef50_UPI000038C5E9 Cluster: COG1446: Asparaginase; n=1; Nostoc
punctiforme PCC 73102|Rep: COG1446: Asparaginase -
Nostoc punctiforme PCC 73102
Length = 290
Score = 52.4 bits (120), Expect = 1e-05
Identities = 34/124 (27%), Positives = 57/124 (45%), Gaps = 3/124 (2%)
Query: 104 VDRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXX 163
+DR N TIG VA+D G +AAGTST G + GR+GD+ + G G Y
Sbjct: 152 IDRPN--TIGCVALDASGVLAAGTSTGGTTKQQQGRVGDTALVGCGLYADNKFGACSTTG 209
Query: 164 XXXVMLRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACH 223
++ + + ++ + P +AA+ A+ + S G ++ + G G A +
Sbjct: 210 DGESIIPVVLAKTAIDFLSGDRHPDEAAQMAIDALVSKVKGEAGCIL-IDRQGRVGWAYN 268
Query: 224 GINM 227
+M
Sbjct: 269 SSHM 272
Score = 38.7 bits (86), Expect = 0.14
Identities = 17/62 (27%), Positives = 34/62 (54%), Gaps = 1/62 (1%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWMKWH 63
GA+ ++ ++H ISVAR ++D K LV +FA++ G + ++++ W +W
Sbjct: 88 GAIAAVQGVRHPISVARKIMD-DKPRLLVARGGERFAIDCGAEMCKKEDLIAEEQWQQWK 146
Query: 64 NE 65
+
Sbjct: 147 ED 148
>UniRef50_Q1GP93 Cluster: Peptidase T2, asparaginase 2 precursor;
n=57; Bacteria|Rep: Peptidase T2, asparaginase 2
precursor - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 353
Score = 52.0 bits (119), Expect = 1e-05
Identities = 31/89 (34%), Positives = 42/89 (47%), Gaps = 1/89 (1%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLR 170
T+G VA D HG++AA TST G K GRIGD+PI G+G Y +R
Sbjct: 219 TVGAVARDTHGNLAAATSTGGLTGKRWGRIGDAPIVGAGTYADDRACAVSATGAGEYFIR 278
Query: 171 FLPSFLTVEEMR-RGSSPTDAAKTAVARI 198
+ +R G S +AA +A +
Sbjct: 279 VGVAHEICARVRLAGQSLQEAADAVMAEV 307
>UniRef50_Q4SA00 Cluster: Chromosome undetermined SCAF14693, whole
genome shotgun sequence; n=6; Eukaryota|Rep: Chromosome
undetermined SCAF14693, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 1438
Score = 51.6 bits (118), Expect = 2e-05
Identities = 24/57 (42%), Positives = 37/57 (64%), Gaps = 1/57 (1%)
Query: 96 LLKKSHLNVDRFNH-DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
L K H+N + NH T+G VA+D+ ++AA +ST G K+ GR+GD+ + G+G Y
Sbjct: 753 LAKLRHINPLKNNHPQTVGAVALDRFQNLAAASSTGGLVGKLKGRVGDTAVAGAGIY 809
Score = 33.9 bits (74), Expect = 3.8
Identities = 15/36 (41%), Positives = 24/36 (66%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQF 39
G+V L+ +K+ I AR V++ + HS +VGE A +F
Sbjct: 692 GSVACLQSVKNPIKAARCVMEQSPHSLIVGEGAEEF 727
>UniRef50_Q4P5A6 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 443
Score = 51.6 bits (118), Expect = 2e-05
Identities = 30/87 (34%), Positives = 42/87 (48%), Gaps = 3/87 (3%)
Query: 63 HNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGD 122
H+ Q N +P P +H+ + +HL D T+G VA+D +G
Sbjct: 218 HSTAAIQANIPSEAESEPELESEP--EHQDQSIFDRYAHLT-DLLPQGTVGAVALDSNGH 274
Query: 123 IAAGTSTNGAKYKIPGRIGDSPIPGSG 149
++ TST G K PGRIGD+P GSG
Sbjct: 275 LSVATSTGGKTNKYPGRIGDTPSVGSG 301
>UniRef50_A6LCT8 Cluster: Asparaginase family protein; n=2;
Bacteroidales|Rep: Asparaginase family protein -
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701
/ NCTC11152)
Length = 332
Score = 51.2 bits (117), Expect = 2e-05
Identities = 33/128 (25%), Positives = 52/128 (40%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLR 170
T+G V +D+ G++ AGTST G K GRIGDSP+ G+G Y +R
Sbjct: 186 TVGCVVLDKQGNLTAGTSTGGMFKKRWGRIGDSPVIGAGTYADNNSCAVSCTGHGEYFIR 245
Query: 171 FLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGAACHGINMFPY 230
+F + + A + + G ++A+ G + MF
Sbjct: 246 HAVAFDVCARYKYLKESVEKAADYIIHTELNTNAGNGGLIAVDKLGNIAMPYNSGGMFRG 305
Query: 231 VVYDKKHS 238
+Y +K S
Sbjct: 306 FLYKEKGS 313
Score = 37.9 bits (84), Expect = 0.24
Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 3/64 (4%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQ--EESLTTSVSKKL 58
++ GAV GL+ +KH I+ A V + H L G A +FA E G + E+++ + K +
Sbjct: 112 LSAGAVAGLKHVKHPINAAYAVKTKSPHVMLSGAGAEEFAKEQGLEMVEDNMYFATPKTM 171
Query: 59 -WMK 61
W++
Sbjct: 172 EWIE 175
>UniRef50_UPI0000E45F91 Cluster: PREDICTED: similar to Tasp1
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Tasp1 protein - Strongylocentrotus
purpuratus
Length = 377
Score = 50.8 bits (116), Expect = 3e-05
Identities = 41/161 (25%), Positives = 72/161 (44%), Gaps = 18/161 (11%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFL----------VGELATQFAVEMGFQEESL 50
++ GAVG L I++ + VA+ +L + L VG A Q+A + GF+E +
Sbjct: 86 LHFGAVGALGGIRNPVKVAKALLCEQRKGLLSHGRIPPCVLVGNGALQWACDHGFKEVNT 145
Query: 51 TTSVSKKLWMKWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHD 110
++ ++ + + F + PD + K + S ++ D D
Sbjct: 146 SSLITPRALSAYRKHKRALTGF-STLPPDQQESLAKRMKGDGS------PVMDGDTMQ-D 197
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
T+G V +D +G IA+ S+ G K PGR+G + G G +
Sbjct: 198 TVGAVCVDSNGQIASAVSSGGIALKHPGRVGHAMCFGCGCW 238
>UniRef50_A1CEN4 Cluster: Asparaginase, putative; n=4;
Trichocomaceae|Rep: Asparaginase, putative - Aspergillus
clavatus
Length = 482
Score = 50.8 bits (116), Expect = 3e-05
Identities = 21/39 (53%), Positives = 28/39 (71%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
T+G V +D+ GD+A TST G K+PGRIGD+P G+G
Sbjct: 227 TVGCVCLDRWGDLAVATSTGGLTNKLPGRIGDTPTLGAG 265
>UniRef50_A6G504 Cluster: Peptidase T2, asparaginase 2; n=1;
Plesiocystis pacifica SIR-1|Rep: Peptidase T2,
asparaginase 2 - Plesiocystis pacifica SIR-1
Length = 305
Score = 50.0 bits (114), Expect = 5e-05
Identities = 26/89 (29%), Positives = 40/89 (44%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVML 169
DT+G V D G++ A ST G K+PGR+GD+PI G+G Y ++
Sbjct: 168 DTVGAVVRDHRGELCALGSTGGVLLKLPGRVGDTPIIGAGFYAHPELGAAVATGVGEALM 227
Query: 170 RFLPSFLTVEEMRRGSSPTDAAKTAVARI 198
+ + + + G AA+ A I
Sbjct: 228 QRVACHELLRRVAAGQPAQAAAEALCAEI 256
Score = 42.7 bits (96), Expect = 0.008
Identities = 19/41 (46%), Positives = 28/41 (68%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMG 44
GA+ +R + A VAR V+DH++H+ LVGE A +FA+ G
Sbjct: 95 GAIASVRDLADACVVARAVMDHSRHALLVGEGARRFALAQG 135
>UniRef50_UPI000051A5AD Cluster: PREDICTED: similar to Threonine
aspartase 1 (Taspase-1); n=1; Apis mellifera|Rep:
PREDICTED: similar to Threonine aspartase 1 (Taspase-1)
- Apis mellifera
Length = 351
Score = 49.6 bits (113), Expect = 7e-05
Identities = 42/192 (21%), Positives = 77/192 (40%), Gaps = 24/192 (12%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLWM 60
+ GAVG + IK+ + +A+ + +H G + F V G
Sbjct: 90 LQFGAVGAVSGIKNPVLLAKRLCEHQSVKIAYGRIPPSFLVGNGAHV------------- 136
Query: 61 KWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNH---DTIGMVAI 117
W E Q +SP+ + + +++ ++ S+ +V ++ DT+G + +
Sbjct: 137 -WAQEMRIQ-----TLSPEQLISTKAQKMYKHYKRKIENSNADVQKYTKQRMDTVGAICV 190
Query: 118 DQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG--AYXXXXXXXXXXXXXXXVMLRFLPSF 175
D+ G+IA S+ G K PGR+G + + G G AY ++R L +
Sbjct: 191 DKEGNIAGACSSGGIILKYPGRVGQAGMWGCGTWAYKDKYSIGTSTSGCGEHLIRTLLAR 250
Query: 176 LTVEEMRRGSSP 187
E + S P
Sbjct: 251 TVAEAISHSSCP 262
>UniRef50_Q3UJT0 Cluster: TIB-55 BB88 cDNA, RIKEN full-length
enriched library, clone:I730051L04 product:Threonine
aspartase 1 (EC 3.4.25.-) (Taspase 1) homolog; n=9;
Amniota|Rep: TIB-55 BB88 cDNA, RIKEN full-length
enriched library, clone:I730051L04 product:Threonine
aspartase 1 (EC 3.4.25.-) (Taspase 1) homolog - Mus
musculus (Mouse)
Length = 383
Score = 49.6 bits (113), Expect = 7e-05
Identities = 45/161 (27%), Positives = 66/161 (40%), Gaps = 21/161 (13%)
Query: 1 MNIGAVGGLRRIKHAISVARHVL-DHTKHSFLVGELATQFAVEMGFQEESLTTSVSKKLW 59
+N GAVG L IK+ +SVA +L + K G + F V G W
Sbjct: 125 LNFGAVGALSGIKNPVSVAHRLLCEGQKGKLSAGRIPPCFLVGEGAYR-----------W 173
Query: 60 MKWHNEHHCQPN-----FWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNH----D 110
H C P+ F L R ++ E LK+ + + N D
Sbjct: 174 AVDHGIPSCPPSTMTTRFSLAAFKRNKRKLELAERVETDFIQLKRRRQSSAKENDSGTLD 233
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
T+G V +D G++AA S+ G K PGR+G + + G G +
Sbjct: 234 TVGAVVVDHEGNVAAAVSSGGLALKHPGRVGQAALYGCGCW 274
>UniRef50_Q0U541 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 417
Score = 48.8 bits (111), Expect = 1e-04
Identities = 21/39 (53%), Positives = 24/39 (61%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
T G V +D HG I TST G K PGRIGD+P G+G
Sbjct: 202 TCGAVVVDSHGTICVATSTGGLTNKAPGRIGDTPCMGTG 240
>UniRef50_Q0TZH7 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 575
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/71 (40%), Positives = 42/71 (59%), Gaps = 12/71 (16%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHS---------FLVGELATQFAVEMG---FQEESLT 51
GAVG + +IK+ IS+AR V +HT HS LV + AT FAVEMG ++L
Sbjct: 55 GAVGAVAQIKNPISLARLVHEHTMHSLTLRRVPPNLLVSQGATDFAVEMGMPILPHDALI 114
Query: 52 TSVSKKLWMKW 62
+ +K+ W++W
Sbjct: 115 SPAAKERWLRW 125
Score = 42.7 bits (96), Expect = 0.008
Identities = 18/41 (43%), Positives = 26/41 (63%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGA 150
DT+G +A+D G+IA G S+ G K GR+G + + G GA
Sbjct: 382 DTVGAIAVDSWGNIACGASSGGIGMKYRGRVGPAALVGVGA 422
>UniRef50_UPI0000E4D55A Cluster: UPI0000E4D55A related cluster; n=1;
Danio rerio|Rep: UPI0000E4D55A UniRef100 entry - Danio
rerio
Length = 261
Score = 48.4 bits (110), Expect = 2e-04
Identities = 42/157 (26%), Positives = 69/157 (43%), Gaps = 12/157 (7%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFL-VGELATQFAVEMGFQEESLTTSVSKKLW 59
+N GAVG L IK+ + V+R +L T+ L G + F V G ++ +++ +
Sbjct: 57 LNYGAVGALSGIKNPVLVSRRLLSETQKGKLSAGRIPPCFLVGKGAEQWAISHGIPACPT 116
Query: 60 MKWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNH-----DTIGM 114
K + F L+ R ++ E KK V+ + DT+G
Sbjct: 117 EKMTTK------FSLSGYKRNKRKMELAEQVETKRFTKKKKKKPVEGEENNSACLDTVGA 170
Query: 115 VAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
V +D G++AA S+ G K PGR+G + G G +
Sbjct: 171 VVVDWEGNVAAAVSSGGLAMKHPGRVGQAAHYGCGCW 207
>UniRef50_A4KSC8 Cluster: Asparaginase; n=10; Francisella
tularensis|Rep: Asparaginase - Francisella tularensis
subsp. holarctica 257
Length = 287
Score = 48.4 bits (110), Expect = 2e-04
Identities = 21/34 (61%), Positives = 26/34 (76%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSP 144
TIG+VA+D G I A TST GA ++ PGR+GDSP
Sbjct: 155 TIGVVALDSKGKICAVTSTGGAGFEYPGRVGDSP 188
>UniRef50_A6RA67 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 477
Score = 48.4 bits (110), Expect = 2e-04
Identities = 21/39 (53%), Positives = 27/39 (69%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
T+G V +D+ G+IA TST G K PGRIGD+P G+G
Sbjct: 178 TVGCVCLDRWGNIAVATSTGGLTNKCPGRIGDTPTLGAG 216
>UniRef50_Q9P6N7 Cluster: L-asparaginase; n=1; Schizosaccharomyces
pombe|Rep: L-asparaginase - Schizosaccharomyces pombe
(Fission yeast)
Length = 285
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/42 (50%), Positives = 29/42 (69%)
Query: 108 NHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
+ DTIG++ +D++G IA +S+ G K GRIG SPIPG G
Sbjct: 173 SQDTIGVICVDKNGRIAVVSSSGGLLLKPAGRIGSSPIPGHG 214
>UniRef50_Q2ULY7 Cluster: Asparaginase; n=2; Aspergillus|Rep:
Asparaginase - Aspergillus oryzae
Length = 445
Score = 48.0 bits (109), Expect = 2e-04
Identities = 21/43 (48%), Positives = 26/43 (60%)
Query: 107 FNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
F+ T+G V +D G +A TST G K PGRIGD+P G G
Sbjct: 201 FSQGTVGCVCLDMWGGVAVATSTGGLTNKWPGRIGDTPTLGGG 243
>UniRef50_A2RAH7 Cluster: Catalytic activity:; n=3; Aspergillus|Rep:
Catalytic activity: - Aspergillus niger
Length = 486
Score = 48.0 bits (109), Expect = 2e-04
Identities = 23/48 (47%), Positives = 33/48 (68%), Gaps = 1/48 (2%)
Query: 102 LNVDRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
+++DR N DT+G +AID G+IAAG+S+ G K GRIG + + G G
Sbjct: 285 MDIDRVN-DTVGAIAIDSKGNIAAGSSSGGIGMKHRGRIGPAALVGIG 331
Score = 38.3 bits (85), Expect = 0.18
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 12/74 (16%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHS---------FLVGELATQFAVEMG---FQEESLT 51
GAVG + ++K+ IS+AR +LD + S FLVG+ AT FA E G + L
Sbjct: 96 GAVGAVGQVKNPISLARVILDASSKSLSLARVPPNFLVGQGATDFAYEHGLVVLPPDGLV 155
Query: 52 TSVSKKLWMKWHNE 65
+++ W W +
Sbjct: 156 APSARERWTHWKRD 169
>UniRef50_Q5UXA3 Cluster: Asparaginase family protein; n=4;
Halobacteriaceae|Rep: Asparaginase family protein -
Haloarcula marismortui (Halobacterium marismortui)
Length = 294
Score = 48.0 bits (109), Expect = 2e-04
Identities = 60/220 (27%), Positives = 89/220 (40%), Gaps = 33/220 (15%)
Query: 3 IGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVEMGFQE-ESLTTSVSKKLWMK 61
+GA + + HA VA V T H L G+ A +FA G + LTT+ +++ + +
Sbjct: 94 VGAACAMSGVVHAADVAHTVATETPHVLLAGDEAVEFAAGTGVETGRDLTTAETRQRYER 153
Query: 62 WHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHG 121
DP GP ++ + H + DT+G VA D G
Sbjct: 154 ----------------ADPPDG-GPADHLDWV-----REHFS----GTDTVGAVATD--G 185
Query: 122 D-IAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRFLPSFLTVEE 180
D +AA TST G + + GR+GD P G+G Y + RF + V E
Sbjct: 186 DRLAAATSTAGRWFALAGRVGDVPQVGAGFYADGRGGASATGEGEAI-ARFGVARRAV-E 243
Query: 181 MRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGEYGA 220
+ P AA+ A+A G V+ L + G GA
Sbjct: 244 LLDTYGPKQAAEEAIAEFEDATGGRAG-VIVLDHAGHTGA 282
>UniRef50_Q2GRS5 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 460
Score = 46.8 bits (106), Expect = 5e-04
Identities = 19/39 (48%), Positives = 26/39 (66%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
T+G VA+D+ G + TST G K+ GRIGD+P G+G
Sbjct: 224 TVGAVAVDEEGVVCVATSTGGLTNKVTGRIGDTPTVGAG 262
>UniRef50_Q9VUX9 Cluster: CG5241-PA; n=4; Diptera|Rep: CG5241-PA -
Drosophila melanogaster (Fruit fly)
Length = 365
Score = 46.4 bits (105), Expect = 7e-04
Identities = 47/204 (23%), Positives = 82/204 (40%), Gaps = 18/204 (8%)
Query: 1 MNIGAVGGLRRIKHAISVARHV---------LDHTKHSFLVGELATQFAVEMGFQEESLT 51
+N GA + R+K+ I +AR + L+ L G A +A E+G
Sbjct: 84 LNFGACTNVSRVKNPIQLARRICDAQSSPQLLERIPPMILAGTGAEHYADEVGCSMVEPG 143
Query: 52 TSVSKKLWMKWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDT 111
+S K ++ N + + + +N + Q E + + + L DT
Sbjct: 144 VLISSKAKFQF-NHYKSKYDLVVNSRLGKATSEESVQVPEPGNEVELAAAL-------DT 195
Query: 112 IGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLRF 171
+G V +D G+ AAG S+ G K+PGR+G + G+G + +
Sbjct: 196 VGAVCVDGAGNTAAGCSSGGILLKVPGRVGQAATYGAGCWATDTDELAIATCTTG-NGEY 254
Query: 172 LPSFLTVEEMRRGSSPTDAAKTAV 195
L L E+ G+ +D A T++
Sbjct: 255 LMKTLLAREICHGAFSSDCAVTSL 278
>UniRef50_Q7S5Y2 Cluster: Putative uncharacterized protein
NCU05624.1; n=4; Pezizomycotina|Rep: Putative
uncharacterized protein NCU05624.1 - Neurospora crassa
Length = 488
Score = 46.4 bits (105), Expect = 7e-04
Identities = 20/39 (51%), Positives = 26/39 (66%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
T+G VA+D G I TST G K+ GRIGD+P+ G+G
Sbjct: 245 TVGAVALDVEGVICVATSTGGMTNKLTGRIGDTPVVGAG 283
>UniRef50_UPI0000D57224 Cluster: PREDICTED: similar to CG5241-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG5241-PA - Tribolium castaneum
Length = 348
Score = 46.0 bits (104), Expect = 9e-04
Identities = 19/42 (45%), Positives = 27/42 (64%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
DT+G V +D G +AAG S+ G K PGR+G + + SGA+
Sbjct: 172 DTVGAVCVDNSGHVAAGCSSGGILLKRPGRVGQAAVYASGAW 213
>UniRef50_A1CBA9 Cluster: Asparaginase family protein; n=4;
Trichocomaceae|Rep: Asparaginase family protein -
Aspergillus clavatus
Length = 515
Score = 46.0 bits (104), Expect = 9e-04
Identities = 19/42 (45%), Positives = 29/42 (69%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
DT+G +A+D +G+IAAG+S+ G K GR+G + + G G Y
Sbjct: 333 DTVGAIAVDSNGNIAAGSSSGGIGAKHRGRVGPAALVGIGTY 374
Score = 38.7 bits (86), Expect = 0.14
Identities = 24/71 (33%), Positives = 39/71 (54%), Gaps = 12/71 (16%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKH---------SFLVGELATQFAVEMG---FQEESLT 51
GA G + ++K+ IS+AR +L+ + +FLVG+ AT FA E G ++L
Sbjct: 96 GAAGAVAQVKNPISLARVILEASSRPLTCHRVPPNFLVGDGATDFAFEQGLVVLPPDALI 155
Query: 52 TSVSKKLWMKW 62
+ SK+ W +W
Sbjct: 156 SRESKERWHRW 166
>UniRef50_UPI00015B4DAB Cluster: PREDICTED: similar to taspase,
threonine aspartase 1; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to taspase, threonine aspartase 1 -
Nasonia vitripennis
Length = 357
Score = 45.2 bits (102), Expect = 0.002
Identities = 18/42 (42%), Positives = 28/42 (66%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
DT+G V IDQ+G++A+ S+ G K PGR+G + + G G +
Sbjct: 183 DTVGAVCIDQYGNVASACSSGGIILKYPGRVGQAGVWGCGVW 224
>UniRef50_Q54RC1 Cluster: Putative asparaginase 2; n=1;
Dictyostelium discoideum AX4|Rep: Putative asparaginase
2 - Dictyostelium discoideum AX4
Length = 589
Score = 45.2 bits (102), Expect = 0.002
Identities = 45/170 (26%), Positives = 80/170 (47%), Gaps = 23/170 (13%)
Query: 3 IGAVGGLRR-IKHAISVARHVLD--HTKH------SFLVGELATQFAVEMGFQE------ 47
+G+VGG++ IK + + R L +TK LVGE A ++A G +
Sbjct: 216 VGSVGGVKNPIKLSAELLRKQLHKGNTKSLGRQRPMILVGEGAKEWASNHGLETFDSNQL 275
Query: 48 ---ESLTTSVSKKLWMKWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNV 104
+ L T S W+K+ ++ NF + Q+H Y+ + + N
Sbjct: 276 LLGDPLITQQSNVNWLKYKSKLENFKNFKHYYKQQEQQQDEQQQQH-YNEDENENENEN- 333
Query: 105 DRFN---HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
D N +DT+G + +D +G+I++G S+ G K GR+G++ + G+G +
Sbjct: 334 DEGNGDLYDTVGAIVVDWNGNISSGVSSGGIILKHSGRVGEAAVFGAGCW 383
>UniRef50_P74383 Cluster: Putative L-asparaginase; n=11;
Cyanobacteria|Rep: Putative L-asparaginase -
Synechocystis sp. (strain PCC 6803)
Length = 329
Score = 45.2 bits (102), Expect = 0.002
Identities = 33/114 (28%), Positives = 55/114 (48%), Gaps = 6/114 (5%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVMLR 170
TIG+VA+D +G IAAGTST G + GR+ DS +P +G Y ++
Sbjct: 173 TIGVVALDANGKIAAGTSTGGKGLERIGRVSDSAMP-AGNYATRFAGVSCTGVGEDIINE 231
Query: 171 FLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDGE--YGAAC 222
L + + + ++ G + A ++ + D +GA +AL + G +G C
Sbjct: 232 CLAAKVVI-RVKDGQNLAQAMAKSITEALENNTD-LGA-IALDHQGHIAWGKTC 282
>UniRef50_A3J5D1 Cluster: Asparaginase; n=3; Bacteroidetes|Rep:
Asparaginase - Flavobacteria bacterium BAL38
Length = 281
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/33 (57%), Positives = 24/33 (72%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDS 143
T+G VA+D +G IA TST G ++IPGRI DS
Sbjct: 155 TVGCVALDNNGKIAVATSTGGKGFEIPGRISDS 187
>UniRef50_A6QTZ1 Cluster: Predicted protein; n=2; Onygenales|Rep:
Predicted protein - Ajellomyces capsulatus NAm1
Length = 473
Score = 44.0 bits (99), Expect = 0.004
Identities = 19/40 (47%), Positives = 27/40 (67%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
DT+G +A+D HG+IAAG+S+ G K GR G + + G G
Sbjct: 351 DTVGAIAVDCHGNIAAGSSSGGIGMKHSGRTGPAALVGVG 390
Score = 39.1 bits (87), Expect = 0.10
Identities = 28/74 (37%), Positives = 40/74 (54%), Gaps = 12/74 (16%)
Query: 4 GAVGGLRRIKHAISVARHVLD-HTK--------HSFLVGELATQFAVEMG---FQEESLT 51
GAVG + IK+ IS+AR VLD TK + LVG AT+FA E G + L
Sbjct: 100 GAVGAVEHIKNPISLARLVLDVSTKPLSLNRVPPNLLVGPGATEFAYENGMPVLHADFLV 159
Query: 52 TSVSKKLWMKWHNE 65
+ S++ W++W +
Sbjct: 160 SGGSRERWLRWKRD 173
>UniRef50_O65268 Cluster: Putative L-asparaginase 4 precursor (EC
3.5.1.1) (L-asparagine amidohydrolase 4) [Contains:
L-asparaginase 4 subunit alpha; L- asparaginase 4
subunit beta]; n=6; Magnoliophyta|Rep: Putative
L-asparaginase 4 precursor (EC 3.5.1.1) (L-asparagine
amidohydrolase 4) [Contains: L-asparaginase 4 subunit
alpha; L- asparaginase 4 subunit beta] - Arabidopsis
thaliana (Mouse-ear cress)
Length = 407
Score = 44.0 bits (99), Expect = 0.004
Identities = 18/42 (42%), Positives = 27/42 (64%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
DT+G++ +D G IA G+S+ G KI GR+G + GSG +
Sbjct: 220 DTVGVICVDNEGHIACGSSSGGIAMKISGRVGLAATYGSGCW 261
>UniRef50_UPI000023D475 Cluster: hypothetical protein FG10857.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG10857.1 - Gibberella zeae PH-1
Length = 548
Score = 43.6 bits (98), Expect = 0.005
Identities = 20/40 (50%), Positives = 27/40 (67%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
DTIG +AID G+IAAG+S+ G K GR+G + + G G
Sbjct: 352 DTIGAIAIDDQGNIAAGSSSGGIGMKHRGRLGPAALVGVG 391
>UniRef50_A5V870 Cluster: Peptidase T2, asparaginase 2 precursor;
n=1; Sphingomonas wittichii RW1|Rep: Peptidase T2,
asparaginase 2 precursor - Sphingomonas wittichii RW1
Length = 318
Score = 43.6 bits (98), Expect = 0.005
Identities = 21/43 (48%), Positives = 27/43 (62%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
+ T+G VA D G +AA TST G K RIGDSP+ G+G +
Sbjct: 182 YGTVGAVARDDKGRLAAATSTGGLTGKRWNRIGDSPVIGAGTW 224
>UniRef50_Q5DEJ8 Cluster: SJCHGC02349 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC02349 protein - Schistosoma
japonicum (Blood fluke)
Length = 368
Score = 43.6 bits (98), Expect = 0.005
Identities = 46/166 (27%), Positives = 73/166 (43%), Gaps = 28/166 (16%)
Query: 1 MNIGAVGGLRRIKHAISVARHVL----DH-------TKHSFLVGELATQFAVEMGFQ--E 47
+ +G +R +++ + VAR +L DH S LVG+ A +A G+
Sbjct: 86 LRFAGIGAVRNMRNPVKVARLLLQSQIDHPLGELGRVPPSLLVGDGAHLWASSKGYSIDN 145
Query: 48 ESLTTSVSKKLWMKWHNEHHCQPNFWL--NVSPDPTRNCGPYQKHEYSHHLLKKSHLNVD 105
++L T S W K+ + WL + D T N + HE + + K+S +
Sbjct: 146 KNLVTKDSLFSWEKYKS--------WLFNGNNIDVTANNPHFTNHE-NCSIPKRSRTH-- 194
Query: 106 RFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
DT+G V ID G +AA S+ G K GR+G + G G +
Sbjct: 195 --RLDTVGAVCIDLEGKVAAAVSSGGIAMKYEGRLGQACAYGCGCW 238
>UniRef50_UPI0000D56B77 Cluster: PREDICTED: similar to asparaginase
like 1; n=1; Tribolium castaneum|Rep: PREDICTED: similar
to asparaginase like 1 - Tribolium castaneum
Length = 282
Score = 43.2 bits (97), Expect = 0.006
Identities = 18/40 (45%), Positives = 25/40 (62%)
Query: 112 IGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
+G +A+D G +AA +ST G + PGR DS I G+G Y
Sbjct: 186 VGAIAVDAQGRVAAASSTGGRLARAPGRCSDSAIVGAGLY 225
Score = 33.5 bits (73), Expect = 5.1
Identities = 16/39 (41%), Positives = 24/39 (61%)
Query: 4 GAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVE 42
G V ++ + H IS+AR V++ + H L GE A +FA E
Sbjct: 108 GGVTVVKNVAHPISLARLVMEKSPHFLLAGEGAKKFAKE 146
>UniRef50_A2XLP6 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 482
Score = 43.2 bits (97), Expect = 0.006
Identities = 15/57 (26%), Positives = 31/57 (54%)
Query: 78 PDPTRNCGPYQKHEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGDIAAGTSTNGAKY 134
P P + G + KHEY ++++ + N F H+ +G + ++ ++ +G NG +Y
Sbjct: 60 PAPDDDPGNFDKHEYRRKMIRQGNYNRKSFGHEILGAINLEYTSELISGMERNGGEY 116
>UniRef50_A7E9Y4 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 490
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/39 (48%), Positives = 24/39 (61%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
T G V +D G + GTST G K+ GRIGD+P G+G
Sbjct: 238 TCGAVCLDSDGVLCVGTSTGGMTNKLTGRIGDTPTLGAG 276
>UniRef50_Q9P6D1 Cluster: Related to asparaginase; n=2;
Sordariales|Rep: Related to asparaginase - Neurospora
crassa
Length = 606
Score = 41.5 bits (93), Expect = 0.019
Identities = 20/40 (50%), Positives = 26/40 (65%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
DT+G +AID G IAAG+S+ G K GRIG + + G G
Sbjct: 424 DTVGAIAIDLKGRIAAGSSSGGIGIKHRGRIGPAALVGIG 463
>UniRef50_A6S1U0 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 662
Score = 41.5 bits (93), Expect = 0.019
Identities = 23/60 (38%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 90 HEYSHHLLKKSHLNVDRFNHDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
HE L +VD DT+G +AID +G IAA +S+ G K GR+G + + G G
Sbjct: 460 HESIPEPLTPEKADVDLIT-DTVGAIAIDMYGRIAAASSSGGIGMKHRGRVGPAALVGIG 518
>UniRef50_A4R4C7 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 585
Score = 41.5 bits (93), Expect = 0.019
Identities = 18/41 (43%), Positives = 27/41 (65%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
+DT+G++AID G IAA +S+ G K GR+G + + G G
Sbjct: 399 YDTVGVIAIDYQGHIAAASSSGGIGMKHRGRVGPAALVGIG 439
>UniRef50_Q7NPM0 Cluster: L-asparaginase; n=1; Gloeobacter
violaceus|Rep: L-asparaginase - Gloeobacter violaceus
Length = 287
Score = 40.3 bits (90), Expect = 0.044
Identities = 31/108 (28%), Positives = 47/108 (43%), Gaps = 4/108 (3%)
Query: 109 HDTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSGAYXXXXXXXXXXXXXXXVM 168
H T+G A+D G +AA TST G GR+ DS P +G Y ++
Sbjct: 158 HGTVGAAAVDGEGGLAAATSTGGRFMAGVGRVSDSCTP-AGNYATDRCAVSCTGHGEDIL 216
Query: 169 LRFLPSFLTVEEMRRGSSPTDAAKTAVARIASHYPDFMGAVVALKNDG 216
L + + + + G S A + + A S DF A +A+ +DG
Sbjct: 217 DEALAARIAI-RVDDGMSLQRAFERSFAEAESRGRDF--AAIAVDSDG 261
>UniRef50_Q01KK7 Cluster: OSIGBa0118P15.4 protein; n=17; Oryza
sativa|Rep: OSIGBa0118P15.4 protein - Oryza sativa
(Rice)
Length = 208
Score = 36.3 bits (80), Expect = 0.72
Identities = 17/39 (43%), Positives = 22/39 (56%)
Query: 111 TIGMVAIDQHGDIAAGTSTNGAKYKIPGRIGDSPIPGSG 149
T+G + +G AA S G K+ G IGDSP+ GSG
Sbjct: 75 TVGCAVMHSNGHTAAAMSMGGLMNKMTGCIGDSPLIGSG 113
>UniRef50_Q9XTB8 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 331
Score = 35.5 bits (78), Expect = 1.3
Identities = 17/44 (38%), Positives = 28/44 (63%), Gaps = 1/44 (2%)
Query: 109 HDTIGMVAIDQHG-DIAAGTSTNGAKYKIPGRIGDSPIPGSGAY 151
HDT+G ++I+ + + +GTS+ G K GR+G S + GSG +
Sbjct: 156 HDTVGAISINTNTMNSESGTSSGGIVLKHSGRLGHSCVYGSGTW 199
>UniRef50_A5E466 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 354
Score = 35.1 bits (77), Expect = 1.7
Identities = 15/32 (46%), Positives = 22/32 (68%), Gaps = 1/32 (3%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKIPGRIG 141
DT+G+ I +HG + TS+ G +K+PGRIG
Sbjct: 186 DTVGLTQIKEHGFVMV-TSSGGNFFKLPGRIG 216
>UniRef50_Q82KS4 Cluster: Putative fatty acid desaturase; n=1;
Streptomyces avermitilis|Rep: Putative fatty acid
desaturase - Streptomyces avermitilis
Length = 365
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/53 (32%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
Query: 40 AVEMGFQEESLTTSVSKKLWMKWHNEHHCQPNFWLNVSPDPTRNCGPYQKHEY 92
A +G+ +L VS W+ HN HH PN L++ PD R + +Y
Sbjct: 105 ASAVGYFHANLVNGVSFGWWVNHHNRHHSNPNH-LDMDPDIGRRTAIFDIKQY 156
>UniRef50_A3AK54 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 198
Score = 34.7 bits (76), Expect = 2.2
Identities = 17/42 (40%), Positives = 26/42 (61%)
Query: 1 MNIGAVGGLRRIKHAISVARHVLDHTKHSFLVGELATQFAVE 42
+ GAV GL + +A+S+AR V++ T H +L + A FA E
Sbjct: 121 LRCGAVSGLSTVVNAVSLARLVMEKTPHIYLAFDGAEAFARE 162
>UniRef50_A7HXC8 Cluster: Alpha amylase catalytic region; n=1;
Parvibaculum lavamentivorans DS-1|Rep: Alpha amylase
catalytic region - Parvibaculum lavamentivorans DS-1
Length = 549
Score = 34.3 bits (75), Expect = 2.9
Identities = 20/70 (28%), Positives = 30/70 (42%), Gaps = 3/70 (4%)
Query: 45 FQEESLTTSVSKKLWMKWHN--EHHCQPNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHL 102
FQE L+ K W W + E PN WL+ P + P ++ +Y HH KS
Sbjct: 128 FQESQLSADNPKSDWYVWADAKEDGTVPNNWLSAFGGPAWSWNPVRR-KYYHHKFLKSQP 186
Query: 103 NVDRFNHDTI 112
++ N +
Sbjct: 187 KLNFHNEQVV 196
>UniRef50_P11110 Cluster: Neck protein Gp13; n=11; Viruses|Rep: Neck
protein Gp13 - Bacteriophage T4
Length = 309
Score = 33.5 bits (73), Expect = 5.1
Identities = 19/84 (22%), Positives = 38/84 (45%), Gaps = 2/84 (2%)
Query: 70 PNFWLNVSPDPTRNCGPYQKHE-YSHHLLKKSHLNVDRFNHDTIGMVAIDQHGDIAAGTS 128
P+FW N + + + G +QK++ KS+++ ++ +T+G + +
Sbjct: 159 PDFWFNSANEQLKVMGNFQKYDLIIVESWTKSYIDTNKMVGNTVGYGTVGPQDSWSLSER 218
Query: 129 TNGAKYKIPGR-IGDSPIPGSGAY 151
N + + GR +G P GAY
Sbjct: 219 YNNPDHNLVGRVVGQDPNVKQGAY 242
>UniRef50_A7AQA6 Cluster: Membrane protein, putative; n=1; Babesia
bovis|Rep: Membrane protein, putative - Babesia bovis
Length = 2031
Score = 33.1 bits (72), Expect = 6.7
Identities = 20/56 (35%), Positives = 25/56 (44%), Gaps = 2/56 (3%)
Query: 70 PNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRFN--HDTIGMVAIDQHGDI 123
PN+W N S P + GP E L K L +DR N HD + + Q DI
Sbjct: 33 PNYWENNSEVPQQAAGPIFALEEQRGALTKKPLLIDRNNKHHDRAIEIVLQQGNDI 88
>UniRef50_A0DQ79 Cluster: Chromosome undetermined scaffold_6, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_6,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 665
Score = 33.1 bits (72), Expect = 6.7
Identities = 15/44 (34%), Positives = 28/44 (63%), Gaps = 2/44 (4%)
Query: 65 EHHCQ-PNFWLNVSPDPTRNCGPYQKHEYSHHLLKKSHLNVDRF 107
++H Q PN + N +P+P +N PY + +HH++ ++ N DR+
Sbjct: 563 QYHSQNPNPYYNQNPNPYQNQNPYDQRYGNHHVVGHNN-NPDRY 605
>UniRef50_Q259G2 Cluster: H0124B04.14 protein; n=3; Oryza
sativa|Rep: H0124B04.14 protein - Oryza sativa (Rice)
Length = 355
Score = 32.7 bits (71), Expect = 8.9
Identities = 12/27 (44%), Positives = 19/27 (70%)
Query: 110 DTIGMVAIDQHGDIAAGTSTNGAKYKI 136
DT+G V +D +G+IA+G S+ G K+
Sbjct: 223 DTVGAVCVDAYGNIASGASSGGIALKV 249
>UniRef50_P83451 Cluster:
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (EC
3.5.1.26) (Glycosylasparaginase)
(Aspartylglucosaminidase) (N4-(N-acetyl-beta-
glucosaminyl)-L-asparagine amidase) (AGA) [Contains:
Glycosylasparaginase alpha chain (AGA subunit alpha)
(p18); Glycosylasparaginase beta chain (AGA subunit
beta) (p30)]; n=1; Asobara tabida|Rep:
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase (EC
3.5.1.26) (Glycosylasparaginase)
(Aspartylglucosaminidase) (N4-(N-acetyl-beta-
glucosaminyl)-L-asparagine amidase) (AGA) [Contains:
Glycosylasparaginase alpha chain (AGA subunit alpha)
(p18); Glycosylasparaginase beta chain (AGA subunit
beta) (p30)] - Asobara tabida (Parasitic wasp)
Length = 40
Score = 32.7 bits (71), Expect = 8.9
Identities = 13/20 (65%), Positives = 17/20 (85%)
Query: 111 TIGMVAIDQHGDIAAGTSTN 130
TIG++A+D +G IA GTSTN
Sbjct: 21 TIGIIAVDANGHIAVGTSTN 40
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.320 0.134 0.417
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 277,413,248
Number of Sequences: 1657284
Number of extensions: 10834852
Number of successful extensions: 21603
Number of sequences better than 10.0: 135
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 21333
Number of HSP's gapped (non-prelim): 229
length of query: 248
length of database: 575,637,011
effective HSP length: 99
effective length of query: 149
effective length of database: 411,565,895
effective search space: 61323318355
effective search space used: 61323318355
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 71 (32.7 bits)
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