Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000863-TA|BGIBMGA000863-PA|IPR009053|Prefoldin
(517 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein p... 68 7e-11
AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein ... 66 2e-10
AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens ... 66 2e-10
AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related... 66 2e-10
BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,... 65 5e-10
BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,... 65 5e-10
AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin he... 65 5e-10
AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin he... 65 5e-10
AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY... 65 5e-10
AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein. 65 5e-10
AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein ... 64 9e-10
AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein ... 64 9e-10
AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein ... 64 9e-10
AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein ... 64 9e-10
AF273042-1|AAG34902.1| 685|Homo sapiens CTCL tumor antigen se1-... 64 2e-09
X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein. 63 3e-09
D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 prot... 63 3e-09
Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein. 62 5e-09
D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heav... 62 6e-09
M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protei... 61 8e-09
X64838-1|CAA46050.1| 1427|Homo sapiens restin protein. 60 1e-08
BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein. 60 1e-08
BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein. 59 3e-08
AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain prot... 59 3e-08
AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated pr... 59 3e-08
AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein. 59 3e-08
Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein. 59 4e-08
BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein pr... 58 6e-08
BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open read... 58 6e-08
BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open read... 58 6e-08
BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein. 58 6e-08
U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1 ... 58 7e-08
AK023707-1|BAB14650.1| 435|Homo sapiens protein ( Homo sapiens ... 58 7e-08
BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containi... 58 1e-07
AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen HD-C... 58 1e-07
X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy ch... 57 1e-07
X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain ... 57 1e-07
X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mR... 57 1e-07
X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for ... 57 1e-07
X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 ... 57 1e-07
AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled co... 57 1e-07
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 57 2e-07
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 57 2e-07
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 57 2e-07
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 57 2e-07
BC113524-1|AAI13525.1| 578|Homo sapiens IFT74 protein protein. 56 2e-07
AY040325-1|AAK77221.1| 600|Homo sapiens capillary morphogenesis... 56 2e-07
AL356133-4|CAH72643.1| 600|Homo sapiens intraflagellar transpor... 56 2e-07
Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heav... 56 3e-07
D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heav... 56 3e-07
BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6, ... 56 3e-07
AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110... 56 3e-07
AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110... 56 3e-07
AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110... 56 3e-07
AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein. 56 3e-07
AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein. 56 3e-07
U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protei... 56 4e-07
BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein. 56 4e-07
AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F, 3... 56 4e-07
AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F, 3... 56 4e-07
AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein... 56 4e-07
D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein. 55 5e-07
BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein. 55 5e-07
BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-co... 55 5e-07
AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb ... 55 5e-07
M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein. 55 7e-07
BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,... 55 7e-07
AF092564-1|AAC72361.1| 1202|Homo sapiens chromosome-associated p... 55 7e-07
AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein p... 55 7e-07
AB019987-1|BAA73535.1| 1288|Homo sapiens chromosome-associated p... 55 7e-07
X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein. 54 9e-07
X63105-1|CAA44819.1| 726|Homo sapiens Tpr protein. 54 9e-07
U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein. 54 9e-07
U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein. 54 9e-07
L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory f... 54 9e-07
BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory... 54 9e-07
BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory... 54 9e-07
BC094764-1|AAH94764.1| 692|Homo sapiens TPR protein protein. 54 9e-07
BC016514-1|AAH16514.1| 687|Homo sapiens TPR protein protein. 54 9e-07
AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter r... 54 9e-07
AL136382-1|CAI23513.1| 620|Homo sapiens novel protein protein. 54 9e-07
AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter r... 54 9e-07
AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein. 54 9e-07
AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a varian... 54 9e-07
AB209109-1|BAD92346.1| 1096|Homo sapiens TATA element modulatory... 54 9e-07
BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 54 1e-06
BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/C... 54 1e-06
BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 54 1e-06
BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin rec... 54 1e-06
AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein. 54 1e-06
AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein. 54 1e-06
BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,... 54 2e-06
BC023634-1|AAH23634.2| 383|Homo sapiens IFT74 protein protein. 54 2e-06
AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion prote... 54 2e-06
AY422473-1|AAR13704.1| 1326|Homo sapiens myosin tail domain-cont... 54 2e-06
AL662788-1|CAI95333.1| 1326|Homo sapiens chromosome 9 open readi... 54 2e-06
AL592153-1|CAI95316.1| 1326|Homo sapiens chromosome 9 open readi... 54 2e-06
AL359877-3|CAI94977.1| 1326|Homo sapiens chromosome 9 open readi... 54 2e-06
AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein. 54 2e-06
AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring prot... 54 2e-06
AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein. 54 2e-06
Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated microtub... 53 2e-06
BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein pr... 53 2e-06
BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1, ... 53 2e-06
AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/... 53 2e-06
BC033545-1|AAH33545.1| 700|Homo sapiens cancer antigen 1 protein. 53 3e-06
BC026194-1|AAH26194.1| 700|Homo sapiens cancer antigen 1 protein. 53 3e-06
AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain cont... 53 3e-06
AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain cont... 53 3e-06
AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain cont... 53 3e-06
AL139095-7|CAI16451.1| 847|Homo sapiens cancer antigen 1 protein. 53 3e-06
AL139095-5|CAI16449.1| 545|Homo sapiens cancer antigen 1 protein. 53 3e-06
AK097760-1|BAC05162.1| 824|Homo sapiens protein ( Homo sapiens ... 53 3e-06
AF414185-1|AAO47239.1| 641|Homo sapiens CAGE-1 protein. 53 3e-06
AF272390-1|AAF78783.1| 1742|Homo sapiens myosin 5c protein. 53 3e-06
L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated prote... 52 4e-06
BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein pr... 52 4e-06
AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and Golgi-l... 52 4e-06
M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myo... 52 5e-06
D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein. 52 5e-06
BX537985-1|CAD97945.1| 1202|Homo sapiens hypothetical protein pr... 52 5e-06
BC029420-1|AAH29420.1| 427|Homo sapiens Unknown (protein for IM... 52 5e-06
AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein. 52 5e-06
AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting cit... 52 5e-06
AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein. 52 5e-06
X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain (... 52 6e-06
X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac m... 52 6e-06
U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein. 52 6e-06
BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2, ... 52 6e-06
AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransfera... 52 6e-06
AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa ... 52 6e-06
AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein. 52 6e-06
AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein. 52 6e-06
X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa pro... 51 9e-06
X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal ... 51 9e-06
BC038515-1|AAH38515.1| 796|Homo sapiens CCDC110 protein protein. 51 9e-06
BC028419-1|AAH28419.1| 833|Homo sapiens coiled-coil domain cont... 51 9e-06
AK127744-1|BAC87110.1| 600|Homo sapiens protein ( Homo sapiens ... 51 9e-06
AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein. 51 9e-06
AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein. 51 9e-06
AB080722-1|BAC81776.1| 833|Homo sapiens hypothetical protein pr... 51 9e-06
X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein. 51 1e-05
X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy... 51 1e-05
U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein. 51 1e-05
M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain p... 51 1e-05
M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain p... 51 1e-05
BC020645-1|AAH20645.1| 416|Homo sapiens Unknown (protein for IM... 51 1e-05
AY131226-1|AAN07912.1| 681|Homo sapiens medulloblastoma antigen... 51 1e-05
AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein. 51 1e-05
Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein. 50 1e-05
X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin he... 50 1e-05
M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle... 50 1e-05
L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein. 50 1e-05
EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7, ... 50 1e-05
D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein. 50 1e-05
BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein. 50 1e-05
BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7, ... 50 1e-05
BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7, ... 50 1e-05
BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein. 50 1e-05
BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein. 50 1e-05
BC041160-1|AAH41160.1| 501|Homo sapiens KIAA1212 protein protein. 50 1e-05
BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein. 50 1e-05
AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein ... 50 1e-05
AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antige... 50 1e-05
AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1 prot... 50 1e-05
AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain... 50 1e-05
AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein. 50 1e-05
AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypepti... 50 1e-05
AB067524-1|BAB67830.1| 704|Homo sapiens KIAA1937 protein protein. 50 1e-05
Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9, no... 50 2e-05
M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy cha... 50 2e-05
L06148-1|AAA35921.1| 579|Homo sapiens golgin-165 protein. 50 2e-05
D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein. 50 2e-05
CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein. 50 2e-05
BC060037-1|AAH60037.1| 622|Homo sapiens KIAA1212 protein protein. 50 2e-05
BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for IM... 50 2e-05
BC048203-1|AAH48203.1| 663|Homo sapiens Unknown (protein for IM... 50 2e-05
AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting p... 50 2e-05
AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting p... 50 2e-05
AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting p... 50 2e-05
AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting p... 50 2e-05
AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FH... 50 2e-05
AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens ... 50 2e-05
AF432211-1|AAL99918.1| 460|Homo sapiens CLL-associated antigen ... 50 2e-05
AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy... 50 2e-05
AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2 ... 50 2e-05
AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2... 50 2e-05
M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy ch... 50 3e-05
BC064391-1|AAH64391.1| 474|Homo sapiens coiled-coil domain cont... 50 3e-05
BC036757-1|AAH36757.2| 474|Homo sapiens coiled-coil domain cont... 50 3e-05
AK000990-1|BAA91457.1| 535|Homo sapiens protein ( Homo sapiens ... 50 3e-05
X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein. 49 3e-05
S72869-1|AAC60637.1| 585|Homo sapiens H4(D10S170) protein. 49 3e-05
BC130564-1|AAI30565.1| 905|Homo sapiens KIAA1524 protein. 49 3e-05
BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex pr... 49 3e-05
BC022284-1|AAH22284.1| 334|Homo sapiens Unknown (protein for IM... 49 3e-05
BC017659-1|AAH17659.1| 285|Homo sapiens KIAA1524 protein protein. 49 3e-05
AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex pr... 49 3e-05
AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex pr... 49 3e-05
AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex pr... 49 3e-05
AK022912-1|BAB14305.1| 472|Homo sapiens protein ( Homo sapiens ... 49 3e-05
AF334474-1|AAL11632.1| 905|Homo sapiens p90 autoantigen protein. 49 3e-05
AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-... 49 3e-05
AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golg... 49 3e-05
AB040957-1|BAA96048.1| 884|Homo sapiens KIAA1524 protein protein. 49 3e-05
AB033038-1|BAA86526.2| 802|Homo sapiens KIAA1212 protein protein. 49 3e-05
BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein. 49 5e-05
BC027493-1|AAH27493.1| 691|Homo sapiens Unknown (protein for IM... 49 5e-05
AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein. 49 5e-05
M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myos... 48 6e-05
AL031283-7|CAI21429.1| 647|Homo sapiens forkhead-associated (FH... 48 6e-05
AF308294-1|AAG48261.1| 312|Homo sapiens serologically defined b... 48 6e-05
AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20... 48 6e-05
Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein. 48 8e-05
Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein. 48 8e-05
BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein. 48 8e-05
BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1 (Drosoph... 48 8e-05
AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical rhabdomyos... 48 8e-05
AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein. 48 8e-05
AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1 (Drosoph... 48 8e-05
AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens ... 48 8e-05
AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein. 48 8e-05
AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein p... 48 8e-05
AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein. 48 8e-05
AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein. 48 8e-05
AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein. 48 8e-05
U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-co... 48 1e-04
BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated, coiled-... 48 1e-04
BC077732-1|AAH77732.1| 662|Homo sapiens FKBP15 protein protein. 48 1e-04
AK027406-1|BAB55092.1| 901|Homo sapiens protein ( Homo sapiens ... 48 1e-04
AF254756-1|AAK13079.1| 698|Homo sapiens predicted testis protei... 48 1e-04
AC019097-1|AAY14820.1| 698|Homo sapiens unknown protein. 48 1e-04
AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated, coiled-... 48 1e-04
X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for ... 47 1e-04
U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein. 47 1e-04
CR769776-10|CAI95382.1| 354|Homo sapiens coiled-coil domain con... 47 1e-04
BC127772-1|AAI27773.1| 863|Homo sapiens KIF5C protein protein. 47 1e-04
BC110287-1|AAI10288.1| 725|Homo sapiens KIF5C protein protein. 47 1e-04
BC091490-1|AAH91490.1| 620|Homo sapiens ODF2L protein protein. 47 1e-04
BC030802-1|AAH30802.2| 661|Homo sapiens Similar to ring finger ... 47 1e-04
BC028366-1|AAH28366.1| 698|Homo sapiens testis specific, 10 pro... 47 1e-04
BC018647-1|AAH18647.1| 1001|Homo sapiens ring finger protein 40 ... 47 1e-04
BC011769-1|AAH11769.1| 1001|Homo sapiens ring finger protein 40 ... 47 1e-04
BC006133-1|AAH06133.1| 1001|Homo sapiens ring finger protein 40 ... 47 1e-04
AL136382-2|CAI23514.1| 636|Homo sapiens novel protein protein. 47 1e-04
AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 47 1e-04
AC108512-1|AAX82030.1| 684|Homo sapiens unknown protein. 47 1e-04
AB033055-1|BAA86543.1| 696|Homo sapiens KIAA1229 protein protein. 47 1e-04
AB014561-1|BAA31636.2| 1030|Homo sapiens KIAA0661 protein protein. 47 1e-04
AB011103-1|BAA25457.2| 999|Homo sapiens KIAA0531 protein protein. 47 1e-04
M98776-1|AAB47721.1| 644|Homo sapiens keratin 1 protein. 47 2e-04
AK055217-1|BAB70876.1| 688|Homo sapiens protein ( Homo sapiens ... 47 2e-04
AF237621-1|AAF60327.1| 644|Homo sapiens keratin 1 protein. 47 2e-04
AB053469-1|BAC54108.1| 720|Homo sapiens ELKS gamma protein. 47 2e-04
AB046821-1|BAB13427.1| 690|Homo sapiens KIAA1601 protein protein. 47 2e-04
U29343-1|AAC52049.1| 725|Homo sapiens hyaluronan receptor protein. 46 2e-04
BC025177-1|AAH25177.1| 471|Homo sapiens Unknown (protein for IM... 46 2e-04
AY536375-1|AAT66048.1| 820|Homo sapiens rhabdomyosarcoma antige... 46 2e-04
AY528715-1|AAT44400.1| 1016|Homo sapiens antigen MU-RMS-40.16A p... 46 2e-04
AL832009-1|CAD89912.1| 1177|Homo sapiens hypothetical protein pr... 46 2e-04
AK131080-1|BAC85130.1| 563|Homo sapiens FLJ00279 protein protein. 46 2e-04
AF091711-1|AAD39719.1| 1773|Homo sapiens splice variant AKAP350 ... 46 2e-04
AC004013-1|AAB96867.2| 2058|Homo sapiens unknown protein. 46 2e-04
AB018346-1|BAA34523.1| 1708|Homo sapiens KIAA0803 protein protein. 46 2e-04
M77830-1|AAA85135.1| 2871|Homo sapiens desmoplakin I protein. 46 3e-04
J05211-1|AAA35766.1| 1752|Homo sapiens protein ( Human desmoplak... 46 3e-04
BC107742-1|AAI07743.1| 372|Homo sapiens IFT74 protein protein. 46 3e-04
AL832639-1|CAD89954.1| 1331|Homo sapiens hypothetical protein pr... 46 3e-04
AL031058-1|CAA19927.1| 2871|Homo sapiens desmoplakin protein. 46 3e-04
AF250731-1|AAO27830.1| 713|Homo sapiens centrosomal colon cance... 46 3e-04
BC056146-1|AAH56146.1| 718|Homo sapiens hook homolog 3 (Drosoph... 46 4e-04
AK001254-1|BAA91584.1| 636|Homo sapiens protein ( Homo sapiens ... 46 4e-04
AF241830-1|AAK29204.1| 718|Homo sapiens golgi-associated microt... 46 4e-04
AB014535-1|BAA31610.2| 864|Homo sapiens KIAA0635 protein protein. 46 4e-04
BC063697-1|AAH63697.1| 644|Homo sapiens keratin 1 (epidermolyti... 45 6e-04
BC045832-1|AAH45832.1| 249|Homo sapiens SDCCAG8 protein protein. 45 6e-04
AF304164-1|AAG41947.1| 644|Homo sapiens keratin 1 protein. 45 6e-04
Z75311-1|CAA99729.1| 1318|Homo sapiens RAD50 homologue hsRAD50 p... 45 7e-04
U63139-1|AAB07119.1| 1312|Homo sapiens Rad50 protein. 45 7e-04
L16782-1|AAC37542.1| 566|Homo sapiens putative M phase phosphop... 45 7e-04
BC112391-1|AAI12392.1| 957|Homo sapiens ELKS/RAB6-interacting/C... 45 7e-04
BC111550-1|AAI11551.1| 957|Homo sapiens ERC2 protein protein. 45 7e-04
BC108282-1|AAI08283.1| 723|Homo sapiens Unknown (protein for IM... 45 7e-04
BC101323-1|AAI01324.1| 546|Homo sapiens CTAGE4 protein protein. 45 7e-04
BC073850-1|AAH73850.1| 723|Homo sapiens RAD50 protein protein. 45 7e-04
BC062603-1|AAH62603.1| 557|Homo sapiens Unknown (protein for IM... 45 7e-04
AL590377-2|CAI14630.2| 1406|Homo sapiens chromosome 9 open readi... 45 7e-04
AL354738-1|CAI16195.2| 1406|Homo sapiens chromosome 9 open readi... 45 7e-04
AL354711-1|CAH72682.2| 1406|Homo sapiens chromosome 9 open readi... 45 7e-04
AL162725-3|CAH70424.1| 1406|Homo sapiens chromosome 9 open readi... 45 7e-04
AL133410-1|CAI10975.1| 284|Homo sapiens tropomyosin 2 (beta) pr... 45 7e-04
AL133214-3|CAH70743.2| 1406|Homo sapiens chromosome 9 open readi... 45 7e-04
AK026274-1|BAB15423.1| 310|Homo sapiens protein ( Homo sapiens ... 45 7e-04
AK000283-1|BAA91052.1| 1084|Homo sapiens protein ( Homo sapiens ... 45 7e-04
AF057300-1|AAD50326.1| 1173|Homo sapiens truncated RAD50 protein... 45 7e-04
AF057299-1|AAD50325.1| 1312|Homo sapiens RAD50-2 protein protein. 45 7e-04
AB002376-1|BAA20832.2| 970|Homo sapiens KIAA0378 protein. 45 7e-04
BX538342-1|CAD98105.1| 1122|Homo sapiens hypothetical protein pr... 44 0.001
BC114627-1|AAI14628.1| 790|Homo sapiens SLMAP protein protein. 44 0.001
BC060769-1|AAH60769.2| 1107|Homo sapiens chromosome 6 open readi... 44 0.001
BC050548-1|AAH50548.1| 1127|Homo sapiens KIF4A protein protein. 44 0.001
BC046212-1|AAH46212.1| 364|Homo sapiens Similar to cytomatrix p... 44 0.001
BC003664-1|AAH03664.1| 787|Homo sapiens Unknown (protein for IM... 44 0.001
AY014284-1|AAK27309.1| 699|Homo sapiens nucleoporin NYD-SP7 pro... 44 0.001
AL357752-3|CAI41487.1| 1232|Homo sapiens kinesin family member 4... 44 0.001
AL139398-5|CAI41024.1| 1232|Homo sapiens kinesin family member 4... 44 0.001
AK023677-1|BAB14636.1| 574|Homo sapiens protein ( Homo sapiens ... 44 0.001
AK023385-1|BAB14554.1| 284|Homo sapiens protein ( Homo sapiens ... 44 0.001
AK021596-1|BAB13850.1| 619|Homo sapiens protein ( Homo sapiens ... 44 0.001
AJ271784-1|CAB75427.1| 1232|Homo sapiens chromokinesin protein. 44 0.001
AF179308-1|AAD51855.1| 1232|Homo sapiens KIF4 protein. 44 0.001
DQ109808-1|AAZ83370.1| 2479|Homo sapiens nephrocystin-6 protein. 44 0.001
BC125087-1|AAI25088.1| 568|Homo sapiens CCDC41 protein protein. 44 0.001
BC125086-1|AAI25087.1| 634|Homo sapiens CCDC41 protein protein. 44 0.001
BC109126-1|AAI09127.1| 872|Homo sapiens chromosome 10 open read... 44 0.001
BC086869-1|AAH86869.1| 954|Homo sapiens FLJ25770 protein protein. 44 0.001
BC043398-1|AAH43398.1| 805|Homo sapiens CEP290 protein protein. 44 0.001
BC036225-1|AAH36225.1| 872|Homo sapiens chromosome 10 open read... 44 0.001
BC013023-1|AAH13023.1| 1193|Homo sapiens NUMA1 protein protein. 44 0.001
AY736182-1|AAU86898.1| 1989|Homo sapiens ninein isoform 6 protein. 44 0.001
AL450306-3|CAI17324.2| 1919|Homo sapiens discs, large homolog 5 ... 44 0.001
AL449305-3|CAI10964.1| 1244|Homo sapiens FK506 binding protein 1... 44 0.001
AL449105-1|CAI95402.1| 1244|Homo sapiens FK506 binding protein 1... 44 0.001
AL391421-2|CAI12104.2| 1919|Homo sapiens discs, large homolog 5 ... 44 0.001
AL355378-1|CAI15667.1| 872|Homo sapiens novel protein protein. 44 0.001
AL162742-5|CAI12110.1| 872|Homo sapiens novel protein protein. 44 0.001
AK125925-1|BAC86346.1| 623|Homo sapiens protein ( Homo sapiens ... 44 0.001
AK026958-1|BAB15602.1| 715|Homo sapiens protein ( Homo sapiens ... 44 0.001
AF458591-1|AAM49719.1| 590|Homo sapiens hypothetical protein pr... 44 0.001
AF352033-1|AAL83937.1| 1809|Homo sapiens DLG5 protein. 44 0.001
AF317887-1|AAK01919.1| 589|Homo sapiens monoclonal antibody 3H1... 44 0.001
AF302773-1|AAG33512.2| 2090|Homo sapiens ninein-Lm isoform protein. 44 0.001
AF212162-1|AAF23015.2| 2096|Homo sapiens ninein protein. 44 0.001
AF022655-1|AAC06349.1| 2442|Homo sapiens cep250 centrosome assoc... 44 0.001
AB091676-1|BAC65420.1| 1764|Homo sapiens discs large protein lp-... 44 0.001
AB046785-1|BAB13391.2| 1313|Homo sapiens KIAA1565 protein protein. 44 0.001
AB014574-1|BAA31649.1| 1234|Homo sapiens KIAA0674 protein protein. 44 0.001
AB011155-1|BAA25509.2| 1952|Homo sapiens KIAA0583 protein protein. 44 0.001
BC112148-1|AAI12149.1| 466|Homo sapiens GRINL1A combined protei... 44 0.002
BC101645-1|AAI01646.1| 466|Homo sapiens GRINL1A combined protei... 44 0.002
BC012568-1|AAH12568.1| 605|Homo sapiens coiled-coil domain cont... 44 0.002
AY517557-1|AAT44530.1| 605|Homo sapiens hypothetical rhabdomyos... 44 0.002
AY353057-1|AAQ76833.1| 466|Homo sapiens GRINL1A combined protei... 44 0.002
AY208913-1|AAP41549.1| 445|Homo sapiens GRINL1A complex protein... 44 0.002
AY207459-1|AAP41548.1| 466|Homo sapiens GRINL1A upstream protei... 44 0.002
AY207007-1|AAO39707.1| 550|Homo sapiens GRINL1A complex protein... 44 0.002
AL451125-2|CAI14346.1| 767|Homo sapiens golgi autoantigen, golg... 44 0.002
AL365275-1|CAI40383.1| 1140|Homo sapiens chromosome 6 open readi... 44 0.002
AL354928-1|CAI39632.1| 767|Homo sapiens golgi autoantigen, golg... 44 0.002
AL137009-1|CAI20344.1| 1140|Homo sapiens chromosome 6 open readi... 44 0.002
AL132874-2|CAI42604.1| 1140|Homo sapiens chromosome 6 open readi... 44 0.002
AK131384-1|BAD18535.1| 326|Homo sapiens protein ( Homo sapiens ... 44 0.002
AK055535-1|BAB70944.1| 466|Homo sapiens protein ( Homo sapiens ... 44 0.002
AK023738-1|BAB14662.1| 475|Homo sapiens protein ( Homo sapiens ... 44 0.002
AK000371-1|BAA91119.1| 413|Homo sapiens protein ( Homo sapiens ... 44 0.002
M19267-1|AAA36771.1| 284|Homo sapiens protein ( Human tropomyos... 43 0.002
BX664727-6|CAI39536.1| 823|Homo sapiens ankyrin repeat domain 2... 43 0.002
BC101324-1|AAI01325.1| 546|Homo sapiens LOC441294 protein protein. 43 0.002
BC090932-1|AAH90932.1| 1377|Homo sapiens NIN protein protein. 43 0.002
BC068006-1|AAH68006.1| 627|Homo sapiens ERC1 protein protein. 43 0.002
BC000280-1|AAH00280.1| 471|Homo sapiens MYH10 protein protein. 43 0.002
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 43 0.002
AY333779-1|AAQ76826.1| 414|Homo sapiens GRINL1A complex protein... 43 0.002
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 43 0.002
AL773545-6|CAI12706.1| 823|Homo sapiens ankyrin repeat domain 2... 43 0.002
AL591543-1|CAI17285.1| 992|Homo sapiens ankyrin repeat domain 1... 43 0.002
AL513478-3|CAH72532.1| 823|Homo sapiens ankyrin repeat domain 2... 43 0.002
AK092201-1|BAC03827.1| 284|Homo sapiens protein ( Homo sapiens ... 43 0.002
AF223939-1|AAK00630.1| 2073|Homo sapiens ninein isotype 3 protein. 43 0.002
AF223938-1|AAK00629.1| 2069|Homo sapiens ninein isotype 2 protein. 43 0.002
AF223937-1|AAK00628.1| 2029|Homo sapiens ninein isotype 1 protein. 43 0.002
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 43 0.002
AB095935-1|BAC23111.1| 996|Homo sapiens KIAA2015 protein protein. 43 0.002
U27109-1|AAC52065.1| 1228|Homo sapiens prepromultimerin protein. 43 0.003
M63618-1|AAA35606.1| 2095|Homo sapiens bullous pemphigoid antige... 43 0.003
M25142-1|AAA60387.1| 389|Homo sapiens myosin heavy chain alpha-... 43 0.003
L11690-1|AAA52288.1| 2649|Homo sapiens bullous pemphigoid antige... 43 0.003
BX530088-1|CAI95784.1| 810|Homo sapiens GRIP1 associated protei... 43 0.003
BC064999-1|AAH64999.1| 1068|Homo sapiens DAAM1 protein protein. 43 0.003
BC063848-1|AAH63848.1| 1228|Homo sapiens multimerin 1 protein. 43 0.003
BC060803-1|AAH60803.1| 715|Homo sapiens chromosome 6 open readi... 43 0.003
BC057227-1|AAH57227.1| 318|Homo sapiens Unknown (protein for IM... 43 0.003
BC038428-1|AAH38428.1| 1068|Homo sapiens DAAM1 protein protein. 43 0.003
BC024781-1|AAH24781.1| 662|Homo sapiens Similar to dishevelled ... 43 0.003
BC008345-1|AAH08345.1| 963|Homo sapiens Unknown (protein for IM... 43 0.003
AY027796-1|AAK27377.1| 530|Homo sapiens ninein centrosomal prot... 43 0.003
AY027795-1|AAK27376.1| 573|Homo sapiens ninein centrosomal prot... 43 0.003
AY027794-1|AAK27375.1| 573|Homo sapiens ninein centrosomal prot... 43 0.003
AL590543-3|CAI10943.1| 722|Homo sapiens chromosome 6 open readi... 43 0.003
AL359494-1|CAH71980.1| 722|Homo sapiens chromosome 6 open readi... 43 0.003
AL096710-6|CAI22047.1| 2649|Homo sapiens dystonin protein. 43 0.003
AF352034-1|AAL83938.1| 1809|Homo sapiens DLG5 protein. 43 0.003
AF269167-1|AAG01408.1| 510|Homo sapiens arsenite related gene 1... 43 0.003
AF186776-1|AAG17027.1| 573|Homo sapiens ninein centrosomal prot... 43 0.003
AC093759-2|AAY40957.1| 1228|Homo sapiens unknown protein. 43 0.003
AB208841-1|BAD92078.1| 1585|Homo sapiens Nuclear mitotic apparat... 43 0.003
AB014566-1|BAA31641.1| 1085|Homo sapiens KIAA0666 protein protein. 43 0.003
Z98949-1|CAI17892.1| 2566|Homo sapiens protein ( Human DNA seque... 42 0.004
X65873-1|CAA46703.1| 963|Homo sapiens kinesin heavy chain protein. 42 0.004
X04201-1|CAA27798.1| 285|Homo sapiens protein ( Human skeletal ... 42 0.004
U94780-1|AAB86593.1| 804|Homo sapiens MEA6 protein. 42 0.004
U73682-1|AAB86589.1| 776|Homo sapiens meningioma-expressed anti... 42 0.004
U51587-1|AAB81549.1| 767|Homo sapiens Golgi complex autoantigen... 42 0.004
M10938-1|AAA36153.1| 493|Homo sapiens protein ( Human epidermal... 42 0.004
D87931-1|BAA75636.1| 1388|Homo sapiens Rho kinase protein. 42 0.004
BC126281-1|AAI26282.1| 963|Homo sapiens kinesin family member 5... 42 0.004
BC126279-1|AAI26280.1| 963|Homo sapiens kinesin family member 5... 42 0.004
BC111801-1|AAI11802.1| 703|Homo sapiens ROCK2 protein protein. 42 0.004
BC064355-1|AAH64355.1| 809|Homo sapiens CTAGE5 protein protein. 42 0.004
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 42 0.004
BC051363-1|AAH51363.2| 729|Homo sapiens CTAGE family, member 5 ... 42 0.004
BC047368-1|AAH47368.1| 367|Homo sapiens ODF2L protein protein. 42 0.004
BC037774-1|AAH37774.1| 352|Homo sapiens GCC2 protein protein. 42 0.004
BC008425-1|AAH08425.1| 285|Homo sapiens tropomyosin 3 protein. 42 0.004
BC008407-1|AAH08407.1| 285|Homo sapiens tropomyosin 3 protein. 42 0.004
AL590431-11|CAH71269.1| 284|Homo sapiens tropomyosin 3 protein. 42 0.004
AL161932-2|CAH71618.1| 963|Homo sapiens kinesin family member 5... 42 0.004
AL139008-2|CAM15100.1| 1011|Homo sapiens ankyrin repeat domain 1... 42 0.004
AL080245-1|CAI16965.1| 2566|Homo sapiens protein ( Human DNA seq... 42 0.004
AL079300-1|CAI17881.1| 2566|Homo sapiens protein ( Human DNA seq... 42 0.004
AL022329-3|CAI17968.1| 2566|Homo sapiens protein ( Human DNA seq... 42 0.004
AF485338-1|AAL93149.1| 1498|Homo sapiens golgin-160 protein. 42 0.004
AF461266-1|AAL67520.1| 606|Homo sapiens RUFY2 protein. 42 0.004
AF411980-1|AAL04164.1| 590|Homo sapiens Run- and FYVE-domain co... 42 0.004
AF338234-1|AAN77611.1| 771|Homo sapiens CTAGE-5B protein protein. 42 0.004
AF338233-1|AAN77610.1| 775|Homo sapiens CTAGE-5A protein protein. 42 0.004
AF161352-1|AAF28912.1| 290|Homo sapiens HSPC089 protein. 42 0.004
AF020091-1|AAB69327.1| 622|Homo sapiens smooth muscle myosin he... 42 0.004
AF013570-1|AAB69326.1| 588|Homo sapiens smooth muscle myosin he... 42 0.004
AC018463-2|AAX93049.1| 1337|Homo sapiens unknown protein. 42 0.004
AB209528-1|BAD92765.1| 808|Homo sapiens CTAGE family, member 5 ... 42 0.004
AB040970-1|BAA96061.1| 619|Homo sapiens KIAA1537 protein protein. 42 0.004
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 42 0.004
AB014519-1|BAA31594.2| 1428|Homo sapiens KIAA0619 protein protein. 42 0.004
CR769776-11|CAI95383.1| 823|Homo sapiens ankyrin repeat domain ... 42 0.005
BX649567-2|CAH71137.1| 823|Homo sapiens ankyrin repeat domain 2... 42 0.005
BC049218-1|AAH49218.1| 671|Homo sapiens Unknown (protein for IM... 42 0.005
BC040280-1|AAH40280.1| 413|Homo sapiens CCDC83 protein protein. 42 0.005
BC036527-1|AAH36527.1| 811|Homo sapiens CTAGEP protein protein. 42 0.005
BC032853-1|AAH32853.1| 767|Homo sapiens golgi autoantigen, golg... 42 0.005
BC030701-1|AAH30701.3| 933|Homo sapiens LRRCC1 protein protein. 42 0.005
BC014050-1|AAH14050.1| 495|Homo sapiens centrosomal protein 63k... 42 0.005
BC004527-1|AAH04527.2| 268|Homo sapiens RNF40 protein protein. 42 0.005
AY353060-1|AAQ76836.1| 435|Homo sapiens GRINL1A combined protei... 42 0.005
AY353058-1|AAQ76834.1| 438|Homo sapiens GRINL1A combined protei... 42 0.005
AY341345-1|AAQ76831.1| 397|Homo sapiens GRINL1A combined protei... 42 0.005
AY334560-1|AAQ76827.1| 407|Homo sapiens GRINL1A complex protein... 42 0.005
AY237639-1|AAP75897.1| 438|Homo sapiens GRINL1A upstream protei... 42 0.005
AK097517-1|BAC05084.1| 621|Homo sapiens protein ( Homo sapiens ... 42 0.005
AK093285-1|BAC04121.1| 797|Homo sapiens protein ( Homo sapiens ... 42 0.005
AK057990-1|BAB71626.1| 502|Homo sapiens protein ( Homo sapiens ... 42 0.005
AK027546-1|BAB55190.1| 536|Homo sapiens protein ( Homo sapiens ... 42 0.005
AK022532-1|BAB14081.1| 975|Homo sapiens protein ( Homo sapiens ... 42 0.005
AF265230-1|AAK58539.1| 975|Homo sapiens RING finger protein 20 ... 42 0.005
AB208797-1|BAD92034.1| 1235|Homo sapiens Chromosome-associated k... 42 0.005
AB051551-1|BAB21855.1| 1029|Homo sapiens KIAA1764 protein protein. 42 0.005
Y07759-2|CAA69036.1| 1828|Homo sapiens mysoin heavy chain 12 pro... 42 0.007
Y07759-1|CAA69035.1| 1855|Homo sapiens mysoin heavy chain 12 pro... 42 0.007
U90942-1|AAD00702.1| 1855|Homo sapiens myosin heavy chain 12 pro... 42 0.007
DQ120669-1|ABB92450.1| 681|Homo sapiens rcCTAGE5 protein. 42 0.007
BC115383-1|AAI15384.1| 684|Homo sapiens taxilin beta protein. 42 0.007
BC080545-1|AAH80545.1| 498|Homo sapiens MYH11 protein protein. 42 0.007
BC043153-1|AAH43153.1| 732|Homo sapiens CTAGE6 protein protein. 42 0.007
BC039828-1|AAH39828.1| 1091|Homo sapiens structural maintenance ... 42 0.007
AL831988-1|CAD91140.1| 718|Homo sapiens hypothetical protein pr... 42 0.007
AK223258-1|BAD96978.1| 284|Homo sapiens tropomyosin 2 (beta) is... 42 0.007
AJ310551-1|CAC39248.1| 1091|Homo sapiens SMC6 protein protein. 42 0.007
AC097377-2|AAX88851.1| 1091|Homo sapiens unknown protein. 42 0.007
AB209505-1|BAD92742.1| 1409|Homo sapiens Myosin Va variant protein. 42 0.007
AB209487-1|BAD92724.1| 1409|Homo sapiens Myosin Va variant protein. 42 0.007
Y16789-1|CAA76385.1| 404|Homo sapiens type I hair keratin 3B pr... 41 0.009
D86970-1|BAA13206.2| 2067|Homo sapiens KIAA0216 protein. 41 0.009
BC133019-1|AAI33020.1| 1427|Homo sapiens LOC650001 protein protein. 41 0.009
BC110585-1|AAI10586.1| 975|Homo sapiens ring finger protein 20 ... 41 0.009
BC110584-1|AAI10585.1| 975|Homo sapiens ring finger protein 20 ... 41 0.009
BC039612-1|AAH39612.1| 2002|Homo sapiens MYO18A protein protein. 41 0.009
BC009971-1|AAH09971.1| 404|Homo sapiens keratin 33B protein. 41 0.009
AY703984-1|AAV80770.1| 1581|Homo sapiens SP-A receptor subunit S... 41 0.009
AY642382-1|AAV34207.1| 1135|Homo sapiens GPBP-interacting protei... 41 0.009
AL591377-3|CAH69963.1| 977|Homo sapiens ring finger protein 20 ... 41 0.009
AL353621-9|CAI14618.1| 977|Homo sapiens ring finger protein 20 ... 41 0.009
AK124113-1|BAC85776.1| 444|Homo sapiens protein ( Homo sapiens ... 41 0.009
AK093227-1|BAC04102.1| 550|Homo sapiens protein ( Homo sapiens ... 41 0.009
AK022300-1|BAB14005.1| 746|Homo sapiens protein ( Homo sapiens ... 41 0.009
AK002051-1|BAA92057.1| 333|Homo sapiens protein ( Homo sapiens ... 41 0.009
AF514869-1|AAQ08179.1| 1133|Homo sapiens GPBP-interacting protei... 41 0.009
AF514868-1|AAQ08178.1| 1133|Homo sapiens GPBP-interacting protei... 41 0.009
AF514867-1|AAQ08177.1| 1135|Homo sapiens GPBP-interacting protei... 41 0.009
AF329092-1|AAN16206.1| 764|Homo sapiens GPBP-interacting protei... 41 0.009
AF034802-1|AAC26103.1| 1005|Homo sapiens liprin-beta1 protein. 41 0.009
AB177860-1|BAD66838.1| 1715|Homo sapiens KIAA0216 splice variant... 41 0.009
AB177858-1|BAD66836.1| 2046|Homo sapiens KIAA0216 splice variant... 41 0.009
AB011137-1|BAA25491.2| 641|Homo sapiens KIAA0565 protein protein. 41 0.009
X98801-1|CAA67333.1| 1263|Homo sapiens dynactin protein. 41 0.012
M99061-1|AAC83410.1| 645|Homo sapiens epidermal cytokeratin 2 p... 41 0.012
BX572623-1|CAM12862.1| 664|Homo sapiens novel protein protein. 41 0.012
BC127816-1|AAI27817.1| 416|Homo sapiens Unknown (protein for IM... 41 0.012
BC115384-1|AAI15385.1| 684|Homo sapiens taxilin beta protein. 41 0.012
BC107746-1|AAI07747.1| 218|Homo sapiens Unknown (protein for IM... 41 0.012
BC101322-1|AAI01323.1| 546|Homo sapiens CTAGE4 protein protein. 41 0.012
>AB209996-1|BAE06078.1| 2585|Homo sapiens CENPE variant protein
protein.
Length = 2585
Score = 68.1 bits (159), Expect = 7e-11
Identities = 85/445 (19%), Positives = 191/445 (42%), Gaps = 28/445 (6%)
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES--LE 145
E + +LK ++ E EAL+R+ + +++ E++ + I L +S LE
Sbjct: 525 EKEEMELKLKEKNDLDEFEALERKTKKDQENELSSKVELLREKEDQIKKLQEYIDSQKLE 584
Query: 146 EVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKL- 204
+ +++ SI +TL D ET + + +L S E ++L
Sbjct: 585 NIKMDLSYSLESIEDPKQMKQTLFDA-----ETVALDAKRESAFLRSENLELKEKMKELA 639
Query: 205 --FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE- 261
++Q+ N + E ++++ + LQ +D + NLE
Sbjct: 640 TTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKD-LLCNLEL 698
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNE--KLICDRREFNETMQEKNILLSDLSKKVN 319
E K ++++L++ E++E ++E+ +L+E L + + +Q+K+ L ++ + +
Sbjct: 699 EGKITDLQKELNKEVEENEALREEVILLSELKSLPSEVERLRKEIQDKSEELHIITSEKD 758
Query: 320 KTERELEEKQEQLTHLMEQLNDTEN------NSYKLIENMFNKVSQIASDFKISNQLSCE 373
K E+ K+ ++ L+E++ T++ ++YK + F + DF+ ++ E
Sbjct: 759 KLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLE 818
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQIN-ETQK-NDNAQLLWEAKKQIADLTEQNII 431
++ +S K + + L T+++ +TQ+ + + + E ++ L EQ
Sbjct: 819 ENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQ--- 875
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEV---TLNLKDSSTXXXXXXXXXXXXSNEIEDM 488
L+ R S L+T +E + + ++ + EEV T D ++I D
Sbjct: 876 LENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSDIHDT 935
Query: 489 KTKVMEWKSQFEDLDDVMKQQQKEL 513
++ + Q + + +KQ Q+ +
Sbjct: 936 VNMNIDTQEQLRNALESLKQHQETI 960
Score = 62.1 bits (144), Expect = 5e-09
Identities = 82/425 (19%), Positives = 177/425 (41%), Gaps = 28/425 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K V E +N+ +N I L L +L+ + + + ++ +E+E L
Sbjct: 814 KMVLE-ENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQL 872
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTL 168
K E ++ S + V +TE + ++L + ++ + S+ + +K+
Sbjct: 873 K-EQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSD 931
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVD----- 223
+ + N +LRN+++ L+ + NT K+ E+++ + + E D
Sbjct: 932 IHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQK 991
Query: 224 LLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDE--- 280
++ I+ + L+ + + I +L + K L + S I EK++
Sbjct: 992 MVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKT 1051
Query: 281 NFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLN 340
+ K+ I+M E R +E +++ I+ + + + K E EL ++L + E+L
Sbjct: 1052 DLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKK-EGELSRTCDRLAEVEEKLK 1110
Query: 341 DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLN 400
+ + + + N +++ K N++ L +E +N LTL+ +
Sbjct: 1111 EKSQQLQEKQQQLLNVQEEMSEMQKKINEIE-NLKNELKNK----ELTLEHM-------- 1157
Query: 401 TQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEV 460
ET++ + AQ L E +++ +T++ +LKE ETE L I+ + + +
Sbjct: 1158 ----ETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQT 1213
Query: 461 TLNLK 465
LK
Sbjct: 1214 KEELK 1218
Score = 60.5 bits (140), Expect = 1e-08
Identities = 89/410 (21%), Positives = 181/410 (44%), Gaps = 49/410 (11%)
Query: 86 IAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLE 145
I K N++ + +D +ALK +++++ ++ + + E I + L
Sbjct: 1723 IVSEKTNEISNMQKDLEHSNDALKAQDLKIQ-EELRIAHMHLKEQQETI-------DKLR 1774
Query: 146 EVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKL- 204
+ E K +++ KD L+ K + I EL+ + L ++K + N +K+
Sbjct: 1775 GIVSEKTDKLSNMQKD-------LENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVS 1827
Query: 205 -FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
EQL + Q+ + L+IEN NL Q + L+
Sbjct: 1828 EMEQLKKQIKDQSLTLSK---LEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLE 1884
Query: 264 KTMLVEEKLSEIKEKDENFKQEID---MLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
+ L +E L E K +D +QE+ ML+++ + E + EK I +SD+ K ++K
Sbjct: 1885 RDQL-KESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDK 1943
Query: 321 TERELEEKQEQLTHLM-----------EQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
++ EL++KQ++ H + + L ++ I+ + + S++ ++ N+
Sbjct: 1944 SKDELQKKQDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMDDHYECLNR 2003
Query: 370 LSCELDDESENTYE-----RISLTLDKI-TNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
LS +L+ E E E + +L+L + T HI L T N+ + +++ + K ++
Sbjct: 2004 LSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFT-ANQRCSMEFHRIMKKLKYVLS 2062
Query: 424 DLTEQNIILKERLSQLETE-------NKELLIEIQTVRGSNEEVTLNLKD 466
+T+ E +++ E + KELLI+IQ ++ + + L+D
Sbjct: 2063 YVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRD 2112
Score = 50.8 bits (116), Expect = 1e-05
Identities = 75/399 (18%), Positives = 170/399 (42%), Gaps = 26/399 (6%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEAL--KRENIQMHTSDVMV-VPEIIDSLTEVINT 136
L EK ++ + L K ++ + EAL K + ++ H + + + E + +N
Sbjct: 1313 LNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNM 1372
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTL-LDKLITKNETDINELRNSIKYLESVKS 195
E+ + V+ K I I+ L L K + ++ ++ + L+ ++
Sbjct: 1373 KEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQE 1432
Query: 196 EYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
+ +++L E + V K +EE LK+ + L +
Sbjct: 1433 VLQSESDQLKENIKEIVAKHLETEEE---LKVAHCCLKEQEETINELRVNLSEKETEIST 1489
Query: 256 FIANLEEMKTMLVEEKLSEIKEKDENFK-QEIDMLNEKLICDRREFNETMQEKNILLSDL 314
LE + L + K+ EI EK+E F ++I + EK + + ++F E + K+ L +
Sbjct: 1490 IQKQLEAINDKL-QNKIQEIYEKEEQFNIKQISEVQEK-VNELKQFKEHRKAKDSALQSI 1547
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
K+ + L+E QE++ ++++ + + ++ E + + Q+ + K ++ ++
Sbjct: 1548 ESKMLELTNRLQESQEEIQIMIKEKEEMK----RVQEALQIERDQLKENTK---EIVAKM 1600
Query: 375 DDESENTYERISLTLDKITN----HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI 430
+ E Y+ + +T T I +L Q ETQK N + + ++ + +N+
Sbjct: 1601 KESQEKEYQFLKMTAVNETQEKMCEIEHLKEQF-ETQKL-NLENIETENIRLTQILHENL 1658
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSST 469
E + + E +L +T++ +++ NL+++ T
Sbjct: 1659 ---EEMRSVTKERDDLRSVEETLKVERDQLKENLRETIT 1694
Score = 45.2 bits (102), Expect = 6e-04
Identities = 89/456 (19%), Positives = 189/456 (41%), Gaps = 36/456 (7%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLT---EVINT 136
L+EK T T L+ + + ++++ + + Q + + V E ++ L E
Sbjct: 1480 LSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKA 1539
Query: 137 LTNGFESLEEVALEID--LKKNS-----ITKDNISIKTLLDKL-ITKNETDINELRNSIK 188
+ +S+E LE+ L+++ + K+ +K + + L I +++ N K
Sbjct: 1540 KDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAK 1599
Query: 189 YLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL----LQXXXXXXXXXX 244
ES + EY + + + ++E+ + K+ +N+ ++
Sbjct: 1600 MKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLE 1659
Query: 245 XXXXXXXARDKFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNE 302
RD + E +K ++E L E +D ++E+ +++ L +E E
Sbjct: 1660 EMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHL----KEHQE 1715
Query: 303 TMQEKNILLSDLSKKVNKTERELEEKQEQL----THLMEQLNDTENNSYKLIENMFNKVS 358
T+ + ++S+ + +++ +++LE + L + E+L + K + +K+
Sbjct: 1716 TIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELR-IAHMHLKEQQETIDKLR 1774
Query: 359 QIASD--FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLW 416
I S+ K+SN + +L++ + E+I L + + L +NETQK +
Sbjct: 1775 GIVSEKTDKLSN-MQKDLENSNAKLQEKIQ-ELKANEHQLITLKKDVNETQK--KVSEME 1830
Query: 417 EAKKQIAD--LTEQNIILKE-RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
+ KKQI D LT + ++ L+Q EN E + + R + V LK
Sbjct: 1831 QLKKQIKDQSLTLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKE 1890
Query: 474 XXXXXXXXSNEI-EDMKTKVMEWKSQFEDLDDVMKQ 508
EI +++KT M K E +D + ++
Sbjct: 1891 SLQETKARDLEIQQELKTARMLSKEHKETVDKLREK 1926
Score = 44.4 bits (100), Expect = 0.001
Identities = 86/453 (18%), Positives = 194/453 (42%), Gaps = 43/453 (9%)
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEID 152
+LK+ ++ A+ + ++ + IQ++ S + ++ L + + + N L + ++
Sbjct: 630 ELKEKMKELATTYKQMEND-IQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSL-IDGK 687
Query: 153 LKKNSITKDNISIK-TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
+ K+ + + K T L K + K + LR + L +KS + E+L +++ +
Sbjct: 688 VPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEV-ERLRKEIQDK 746
Query: 212 VDKQNCIQEEVDLLKIEN-------QNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMK 264
++ + I E D L E Q LL+ + D+ N + +
Sbjct: 747 SEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLH 806
Query: 265 TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
M E+K + E++E +N++++ +E + L ++LS K + + +
Sbjct: 807 -MDFEQKYKMVLEENER-------MNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEK 858
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS----NQLSCELDDESEN 380
E QE+L MEQL + N ++ + + + I + + L+ E DD +
Sbjct: 859 TREVQERLNE-MEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDD-LKQ 916
Query: 381 TYERISLTLDKITNHI---TYLNTQINETQKN------DNAQLLWEAKKQIADLTEQNII 431
E + + D++ + I +N E +N + + + K +I++ +N+
Sbjct: 917 LQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLH 976
Query: 432 LKERLSQLETENKELLIEI---QTVRGSN-EEVTLNLKDSS-TXXXXXXXXXXXXSNEIE 486
++E + + E ++ ++ I Q + N + +T ++KD+ NE++
Sbjct: 977 MEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQ 1036
Query: 487 DMKTKVMEWKSQFE-DLDDVMK---QQQKELKL 515
M V+ K Q + DL + ++ + Q+EL+L
Sbjct: 1037 QMLESVIAEKEQLKTDLKENIEMTIENQEELRL 1069
Score = 39.1 bits (87), Expect = 0.037
Identities = 41/159 (25%), Positives = 74/159 (46%), Gaps = 11/159 (6%)
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
E N L +D V E+ EK+E L E+ ND + ++ +E K + K
Sbjct: 504 ELNSLRADYDNLVLDYEQLRTEKEEMELKLKEK-NDLDE--FEALERKTKKDQENELSSK 560
Query: 366 ISNQLSCELDDESENTYERI-SLTLDKITNHITYLNTQINETQKN-----DNAQLLWEAK 419
+ +L E +D+ + E I S L+ I ++Y I + ++ D + +AK
Sbjct: 561 V--ELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPKQMKQTLFDAETVALDAK 618
Query: 420 KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNE 458
++ A L +N+ LKE++ +L T K++ +IQ + E
Sbjct: 619 RESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLE 657
Score = 33.1 bits (72), Expect = 2.4
Identities = 51/261 (19%), Positives = 113/261 (43%), Gaps = 34/261 (13%)
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
K I +L++ + E ++ EKD Q +L EK + + + NE ++ +L
Sbjct: 355 KEIMDLKKQLEEVSLETRAQAMEKD----QLAQLLEEKDLLQKVQ-NEKIENLTRMLVTS 409
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
S + E + + K+ ++T + ++N +N++Y N+ ++ K+S L E+
Sbjct: 410 SSLTLQQELKAKRKR-RVTWCLGKINKMKNSNYADQSNIPTNIT--TKTHKLSINLLREI 466
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
D+ + + S TLD ++ ++ W ++ L ++NI +
Sbjct: 467 DESVCSESDVFSNTLDTLS-------------------EIEWNPATKL--LNQENI--ES 503
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKV-- 492
L+ L + L+++ + +R EE+ L LK+ + ++ ++ +KV
Sbjct: 504 ELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQENELSSKVEL 563
Query: 493 -MEWKSQFEDLDDVMKQQQKE 512
E + Q + L + + Q+ E
Sbjct: 564 LREKEDQIKKLQEYIDSQKLE 584
>AY282407-1|AAP40331.1| 1116|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1116
Score = 66.5 bits (155), Expect = 2e-10
Identities = 97/512 (18%), Positives = 218/512 (42%), Gaps = 43/512 (8%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETK 90
KE+ Q++S ++ + + V + KN E I +L ++ + TK
Sbjct: 227 KEVQQIQSNY--DIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTK 284
Query: 91 HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++L+ L DS S++ + N++ S+ + ++ +++ + ++E ++
Sbjct: 285 IDELRTL--DSVSQISNIDLLNLR-DLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQ 341
Query: 151 IDLKKNSITKDNISIKTLLDKLI---TKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
++NS +I +++ +K I EL I+ L++ Y N +L E+
Sbjct: 342 EPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK 401
Query: 208 LNNAVD-----KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ D K+ IQ+ + L+ +N L + A ++E
Sbjct: 402 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKE 461
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNE-----KLICDRREFNETMQEKNILLSDLSKK 317
++T+L +K+ E+ + K E D+L + KL + +EF E +Q+ DL+ K
Sbjct: 462 LETILETQKV----ERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 517
Query: 318 VNKTERELEE---KQEQLTHLMEQLNDTENNSYKLIENMFNKVS-------QIASDFKIS 367
K + E+ + + + HL++ + E + + E + ++S + +D +
Sbjct: 518 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 577
Query: 368 NQLSCELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDN--AQLLWEAKKQI 422
+ +L ++ + ++I +++ + L +INE +K N +Q L ++ I
Sbjct: 578 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTI 637
Query: 423 ADLTEQ--NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXX 480
L EQ N ++E + Q E K+L ++ + + E++ + L++
Sbjct: 638 QQLKEQLNNQKVEEAIQQYERACKDLNVKEKII----EDMRMTLEEQEQTQVEQDQVLEA 693
Query: 481 XSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
E+E + T++ +WK + DL+ Q+ +
Sbjct: 694 KLEEVERLATELEKWKEKCNDLETKNNQRSNK 725
Score = 52.4 bits (120), Expect = 4e-06
Identities = 85/437 (19%), Positives = 187/437 (42%), Gaps = 41/437 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMH-TSDVMV--VPEIIDSLTEVINTLT 138
E + E +H + L ++ + ++ LK E + + T DV + V E +L+E+ +T
Sbjct: 394 ENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVT 453
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDK--LITKNETDINELRNSIKYLESVKS- 195
++E+ ++ +K + + +L+K +I K E ++ E + ++ +SVK+
Sbjct: 454 CYKAKIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQ--DSVKNT 511
Query: 196 -EYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ N KL E++ N +Q+ LL+++ +
Sbjct: 512 KDLNVKELKLKEEITQLT---NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQ 568
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
A+L+ EE +++KEK + K++I + +K + R+ ++ ++ K +++L
Sbjct: 569 NLKADLQRK-----EEDYADLKEKLTDAKKQIKQV-QKEVSVMRDEDKLLRIK---INEL 619
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
KK N+ +EL+ KQ + L EQLN+ + +E + + D + ++ ++
Sbjct: 620 EKKKNQCSQELDMKQRTIQQLKEQLNNQK------VEEAIQQYERACKDLNVKEKIIEDM 673
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
E E+ + D++ L ++ E ++ W K++ DL +N +
Sbjct: 674 RMTLEE-QEQTQVEQDQV------LEAKLEEVERLATELEKW--KEKCNDLETKN---NQ 721
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
R ++ N ++L ++ ++ +E + E E+++ K E
Sbjct: 722 RSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNK--E 779
Query: 495 WKSQFEDLDDVMKQQQK 511
K ED + KQQ +
Sbjct: 780 MKKYAEDRERFFKQQNE 796
Score = 32.3 bits (70), Expect = 4.2
Identities = 65/350 (18%), Positives = 146/350 (41%), Gaps = 22/350 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTEKLTIA 87
+EI QL + LQ K + +LK +E + ++ L L L
Sbjct: 523 EEITQLTNNLQDM-----KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 577
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E + DLK+ D+ +++ +++E M D ++ +I + L + N + + +
Sbjct: 578 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI-NELEKKKNQCSQELDMKQRT 636
Query: 148 ALEI-DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE 206
++ + N ++ I K + E I ++R +++ E + E + E E
Sbjct: 637 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 696
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM--- 263
++ + +E+ + +E +N + +D+ + ++
Sbjct: 697 EVERLATELEKWKEKCN--DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNAD 754
Query: 264 KTMLVEEKLSEIKE--KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ +EEK+ I + + EN + + +M +K DR F + E IL + L++K +
Sbjct: 755 RKKWLEEKMMLITQAKEAENIRNK-EM--KKYAEDRERFFKQQNEMEILTAQLTEKDSDL 811
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQL 370
++ EE+ + + L QL +++ + +N ++ +I S+ KI Q+
Sbjct: 812 QKWREERDQLVAALEIQLKALISSNVQK-DNEIEQLKRIISETSKIETQI 860
>AK024959-1|BAB15043.1| 696|Homo sapiens protein ( Homo sapiens
cDNA: FLJ21306 fis, clone COL02125. ).
Length = 696
Score = 66.5 bits (155), Expect = 2e-10
Identities = 97/512 (18%), Positives = 218/512 (42%), Gaps = 43/512 (8%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETK 90
KE+ Q++S ++ + + V + KN E I +L ++ + TK
Sbjct: 142 KEVQQIQSNY--DIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTK 199
Query: 91 HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++L+ L DS S++ + N++ S+ + ++ +++ + ++E ++
Sbjct: 200 IDELRTL--DSVSQISNIDLLNLR-DLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQ 256
Query: 151 IDLKKNSITKDNISIKTLLDKLI---TKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
++NS +I +++ +K I EL I+ L++ Y N +L E+
Sbjct: 257 EPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKER 316
Query: 208 LNNAVD-----KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ D K+ IQ+ + L+ +N L + A ++E
Sbjct: 317 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKE 376
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNE-----KLICDRREFNETMQEKNILLSDLSKK 317
++T+L +K+ E+ + K E D+L + KL + +EF E +Q+ DL+ K
Sbjct: 377 LETILETQKV----ERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 432
Query: 318 VNKTERELEE---KQEQLTHLMEQLNDTENNSYKLIENMFNKVS-------QIASDFKIS 367
K + E+ + + + HL++ + E + + E + ++S + +D +
Sbjct: 433 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 492
Query: 368 NQLSCELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDN--AQLLWEAKKQI 422
+ +L ++ + ++I +++ + L +INE +K N +Q L ++ I
Sbjct: 493 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTI 552
Query: 423 ADLTEQ--NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXX 480
L EQ N ++E + Q E K+L ++ + + E++ + L++
Sbjct: 553 QQLKEQLNNQKVEEAIQQYERACKDLNVKEKII----EDMRMTLEEQEQTQVEQDQVLEA 608
Query: 481 XSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
E+E + T++ +WK + DL+ Q+ +
Sbjct: 609 KLEEVERLATELEKWKEKCNDLETKNNQRSNK 640
Score = 51.2 bits (117), Expect = 9e-06
Identities = 75/374 (20%), Positives = 166/374 (44%), Gaps = 31/374 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMH-TSDVMV--VPEIIDSLTEVINTLT 138
E + E +H + L ++ + ++ LK E + + T DV + V E +L+E+ +T
Sbjct: 309 ENNRLKEREHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVT 368
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDK--LITKNETDINELRNSIKYLESVKS- 195
++E+ ++ +K + + +L+K +I K E ++ E + ++ +SVK+
Sbjct: 369 CYKAKIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQ--DSVKNT 426
Query: 196 -EYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ N KL E++ N +Q+ LL+++ +
Sbjct: 427 KDLNVKELKLKEEITQLT---NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQ 483
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
A+L+ EE +++KEK + K++I + +K + R+ ++ ++ K +++L
Sbjct: 484 NLKADLQRK-----EEDYADLKEKLTDAKKQIKQV-QKEVSVMRDEDKLLRIK---INEL 534
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
KK N+ +EL+ KQ + L EQLN+ + +E + + D + ++ ++
Sbjct: 535 EKKKNQCSQELDMKQRTIQQLKEQLNNQK------VEEAIQQYERACKDLNVKEKIIEDM 588
Query: 375 D---DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
+E E T L+ + L T++ + ++ N L + ++ E N
Sbjct: 589 RMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCN-DLETKNNQRSNKEHENNTD 647
Query: 432 LKERLSQLETENKE 445
+ +L+ L+ E +E
Sbjct: 648 VLGKLTNLQDELQE 661
>AB033337-1|BAB69456.1| 1820|Homo sapiens mitotic kinesin-related
protein protein.
Length = 1820
Score = 66.5 bits (155), Expect = 2e-10
Identities = 97/512 (18%), Positives = 218/512 (42%), Gaps = 43/512 (8%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETK 90
KE+ Q++S ++ + + V + KN E I +L ++ + TK
Sbjct: 931 KEVQQIQSNY--DIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTK 988
Query: 91 HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++L+ L DS S++ + N++ S+ + ++ +++ + ++E ++
Sbjct: 989 IDELRTL--DSVSQISNIDLLNLR-DLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQ 1045
Query: 151 IDLKKNSITKDNISIKTLLDKLI---TKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
++NS +I +++ +K I EL I+ L++ Y N +L E+
Sbjct: 1046 EPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK 1105
Query: 208 LNNAVD-----KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ D K+ IQ+ + L+ +N L + A ++E
Sbjct: 1106 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKE 1165
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNE-----KLICDRREFNETMQEKNILLSDLSKK 317
++T+L +K+ E+ + K E D+L + KL + +EF E +Q+ DL+ K
Sbjct: 1166 LETILETQKV----ERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVK 1221
Query: 318 VNKTERELEE---KQEQLTHLMEQLNDTENNSYKLIENMFNKVS-------QIASDFKIS 367
K + E+ + + + HL++ + E + + E + ++S + +D +
Sbjct: 1222 ELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1281
Query: 368 NQLSCELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDN--AQLLWEAKKQI 422
+ +L ++ + ++I +++ + L +INE +K N +Q L ++ I
Sbjct: 1282 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTI 1341
Query: 423 ADLTEQ--NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXX 480
L EQ N ++E + Q E K+L ++ + + E++ + L++
Sbjct: 1342 QQLKEQLNNQKVEEAIQQYERACKDLNVKEKII----EDMRMTLEEQEQTQVEQDQVLEA 1397
Query: 481 XSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
E+E + T++ +WK + DL+ Q+ +
Sbjct: 1398 KLEEVERLATELEKWKEKCNDLETKNNQRSNK 1429
Score = 52.4 bits (120), Expect = 4e-06
Identities = 85/437 (19%), Positives = 187/437 (42%), Gaps = 41/437 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMH-TSDVMV--VPEIIDSLTEVINTLT 138
E + E +H + L ++ + ++ LK E + + T DV + V E +L+E+ +T
Sbjct: 1098 ENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVT 1157
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDK--LITKNETDINELRNSIKYLESVKS- 195
++E+ ++ +K + + +L+K +I K E ++ E + ++ +SVK+
Sbjct: 1158 CYKAKIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQ--DSVKNT 1215
Query: 196 -EYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ N KL E++ N +Q+ LL+++ +
Sbjct: 1216 KDLNVKELKLKEEITQLT---NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQ 1272
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
A+L+ EE +++KEK + K++I + +K + R+ ++ ++ K +++L
Sbjct: 1273 NLKADLQRK-----EEDYADLKEKLTDAKKQIKQV-QKEVSVMRDEDKLLRIK---INEL 1323
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
KK N+ +EL+ KQ + L EQLN+ + +E + + D + ++ ++
Sbjct: 1324 EKKKNQCSQELDMKQRTIQQLKEQLNNQK------VEEAIQQYERACKDLNVKEKIIEDM 1377
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
E E+ + D++ L ++ E ++ W K++ DL +N +
Sbjct: 1378 RMTLEE-QEQTQVEQDQV------LEAKLEEVERLATELEKW--KEKCNDLETKN---NQ 1425
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
R ++ N ++L ++ ++ +E + E E+++ K E
Sbjct: 1426 RSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNK--E 1483
Query: 495 WKSQFEDLDDVMKQQQK 511
K ED + KQQ +
Sbjct: 1484 MKKYAEDRERFFKQQNE 1500
Score = 32.3 bits (70), Expect = 4.2
Identities = 65/350 (18%), Positives = 146/350 (41%), Gaps = 22/350 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTEKLTIA 87
+EI QL + LQ K + +LK +E + ++ L L L
Sbjct: 1227 EEITQLTNNLQDM-----KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1281
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E + DLK+ D+ +++ +++E M D ++ +I + L + N + + +
Sbjct: 1282 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI-NELEKKKNQCSQELDMKQRT 1340
Query: 148 ALEI-DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE 206
++ + N ++ I K + E I ++R +++ E + E + E E
Sbjct: 1341 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 1400
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM--- 263
++ + +E+ + +E +N + +D+ + ++
Sbjct: 1401 EVERLATELEKWKEKCN--DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNAD 1458
Query: 264 KTMLVEEKLSEIKE--KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ +EEK+ I + + EN + + +M +K DR F + E IL + L++K +
Sbjct: 1459 RKKWLEEKMMLITQAKEAENIRNK-EM--KKYAEDRERFFKQQNEMEILTAQLTEKDSDL 1515
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQL 370
++ EE+ + + L QL +++ + +N ++ +I S+ KI Q+
Sbjct: 1516 QKWREERDQLVAALEIQLKALISSNVQK-DNEIEQLKRIISETSKIETQI 1564
>BC104906-1|AAI04907.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 65.3 bits (152), Expect = 5e-10
Identities = 88/457 (19%), Positives = 197/457 (43%), Gaps = 42/457 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E++ E + K+ + + +EL+ L++++ Q+ T + ++ E + + TE+ +
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLLQEQLQAETEL-------Y 903
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE---TDINELRNSIKYLESVKSEYN 198
EE+ + + KK + + ++ L++ + + + ++ + LE E
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
A +KL + A K +++E+ ++ +N L + ++
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 259 NLEEMKTMLVEEKLSEIK---EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
NL ++K E +SE++ +K+E +QE++ L KL D +F+E + + +++L
Sbjct: 1024 NLTKLKNKH-ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1082
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF--------KIS 367
++ K E EL Q L L +++ +NN+ K I + +S + D K
Sbjct: 1083 MQLAKKEEEL---QAALARLDDEIAQ-KNNALKKIRELEGHISDLQEDLDSERAARNKAE 1138
Query: 368 NQ----------LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
Q L EL+D ++T + L K +T L ++E ++ AQ + E
Sbjct: 1139 KQKRDLGEELEALKTELEDTLDSTATQQELRA-KREQEVTVLKKALDEETRSHEAQ-VQE 1196
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
+++ A E+ L E+L Q + L QT+ N ++ L+
Sbjct: 1197 MRQKHAQAVEE---LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1253
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++++++K + + +L+D + + Q E++
Sbjct: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1290
Score = 50.4 bits (115), Expect = 1e-05
Identities = 81/441 (18%), Positives = 175/441 (39%), Gaps = 31/441 (7%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K E K ++ + +++L L +K+ + + + + ++ + L
Sbjct: 1247 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1306
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNIS-- 164
++ + +S + E++ T ++ LEE +L+ L + K N+
Sbjct: 1307 AKDVASL-SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNC 217
I TL +L + ++ + + ++++ LE K + E L +Q A DK +N
Sbjct: 1366 ISTLNIQL-SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424
Query: 218 IQEEVD--LLKIENQNLL---------QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+Q+E+D ++ ++NQ L + RD+ A E +T
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1484
Query: 267 LVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
+ L+ E+ K+E++ N+ L + + + + + +L K E ++E
Sbjct: 1485 ALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1542
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERIS 386
E + QL L ++L TE+ +L NM Q D + ++ + E + +
Sbjct: 1543 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYE 1602
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
L+ L + + D L +A I E+ I ++L +L+ + K+
Sbjct: 1603 TELEDERKQ-RALAAAAKKKLEGDLKDLELQADSAIKG-REEAI---KQLRKLQAQMKDF 1657
Query: 447 LIEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K++
Sbjct: 1658 QRELEDARASRDEIFATAKEN 1678
Score = 50.0 bits (114), Expect = 2e-05
Identities = 93/502 (18%), Positives = 199/502 (39%), Gaps = 41/502 (8%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTE 82
LEE +E + LQ + + +L+ DEI M Q L LT
Sbjct: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLE-DEILVMDDQNNKLSKERKLLEERISDLTT 1013
Query: 83 KLTIAETKHNDLKKL---YEDSASELEA-LKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L E K +L KL +E SELE LK+E ++ L +
Sbjct: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE---------LEKLKRKLEGDA 1064
Query: 139 NGF-ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ F E + ++ +I K + K ++ L +L + +I + N++K + ++
Sbjct: 1065 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARL----DDEIAQKNNALKKIRELEGHI 1120
Query: 198 NTANEKLFEQL---NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ E L + N A ++ + EE++ LK E ++ L
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1180
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE-KLICDRREFNETMQEKNILLSD 313
K + V+E + + E ++++ K D+ + +T++++N L+
Sbjct: 1181 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK--QTLEKENADLAG 1238
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ + + ++E+E K+++L +++L ++ + + +KV K+ N++
Sbjct: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH------KLQNEVESV 1292
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNII 431
+E + I L D + L++Q+ +TQ+ + + ++ L E+
Sbjct: 1293 TGMLNEAEGKAIKLAKD-----VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
L+++L + + L I T+ + L+D ++ EIE++ +
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407
Query: 492 VMEWKSQFEDLDDVMKQQQKEL 513
E + ++ L+ + Q+EL
Sbjct: 1408 YEEKAAAYDKLEKTKNRLQQEL 1429
Score = 44.4 bits (100), Expect = 0.001
Identities = 78/424 (18%), Positives = 177/424 (41%), Gaps = 47/424 (11%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNI 163
E+ LK+ + S V E+ + + LT E + +D K ++ K+N
Sbjct: 1175 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1234
Query: 164 SIKTLLDKLITKNETDINELRNSIK-YLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEE 221
+ L +++ + + ++ + ++ ++ ++S+ + E+ +LN+ V K QN ++
Sbjct: 1235 DLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESV 1292
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN 281
+L N + + + E + + V KL +++E+ +
Sbjct: 1293 TGML-----NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 282 FKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN---KTERELEEKQEQLTHLMEQ 338
+ ++D E ++ + NI LSD KK+ T LEE +++ +E
Sbjct: 1348 LQDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1403
Query: 339 LN---DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE--NTYERISLTLDKIT 393
L + + +Y +E N++ Q D + +LD++ + + E+ D++
Sbjct: 1404 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVV------DLDNQRQLVSNLEKKQRKFDQLL 1457
Query: 394 NHITYLNTQINETQKNDNAQLLWEAKK--QIADLTEQNIILKERLSQLETENKELLIEIQ 451
++++ + + A+ + K +A E+ + KE +LE NK L E++
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE---ELERTNKMLKAEME 1514
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ S ++V N+ + ++T++ E K+Q E+L+D + Q +
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRA--------------LETQMEEMKTQLEELEDEL-QATE 1559
Query: 512 ELKL 515
+ KL
Sbjct: 1560 DAKL 1563
Score = 41.5 bits (93), Expect = 0.007
Identities = 68/328 (20%), Positives = 135/328 (41%), Gaps = 30/328 (9%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + + N +K ++ L++ + +++EL S + LE+ E T E+
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + LK + + LQ R + L E
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEK---------RRQLQRQLHEY 1601
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+T L +E+ K E D+ + +L D + +E L L ++ +R
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--KGREEAIKQLRKLQAQMKDFQR 1659
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
ELE+ + + + E + L ++ +A+ + Q E ++ +E
Sbjct: 1660 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS 1719
Query: 384 RIS----LTLDK--ITNHITYLNTQINETQKN-----DNAQLLWEAKKQIAD--LTEQNI 430
+S L +K + I L ++ E Q N D + + +Q+++ TE++
Sbjct: 1720 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERST 1779
Query: 431 ILKERLS--QLETENKELLIEIQTVRGS 456
K + QLE +NKEL ++ + G+
Sbjct: 1780 AQKNESARQQLERQNKELRSKLHEMEGA 1807
Score = 37.9 bits (84), Expect = 0.085
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 252 ARDKFIANLEE--MKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQE 306
+RD+ A +E K +E L +++E E +++ D+ E+L E ++
Sbjct: 1667 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA---EELASSLSG 1723
Query: 307 KNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+N L + L ++ + E ELEE+Q + + +++ + +L + + S +
Sbjct: 1724 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1783
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
QL + + +E K + I L +I + ++ Q E +
Sbjct: 1784 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE-QEAREKQAATK 1842
Query: 424 DLTEQNIILKERLSQLETENK 444
L +++ LKE L Q+E E K
Sbjct: 1843 SLKQKDKKLKEILLQVEDERK 1863
Score = 36.7 bits (81), Expect = 0.20
Identities = 43/237 (18%), Positives = 98/237 (41%), Gaps = 15/237 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E D+ +L+ + E + + + E+L E+L +++ +N +Q+E L+ + Q
Sbjct: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE---ARIAQLE 1742
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICD 296
K E++ L E+ +K+E+ +Q+++ N++L
Sbjct: 1743 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATER--STAQKNESARQQLERQNKELRSK 1800
Query: 297 RREFNETMQEK-NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKL---IEN 352
E ++ K ++ L K+ + E ++E++ + + L + ++ +E+
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
Query: 353 MFNKVSQIASDFKISN----QLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
Q + N QL +L +E+E +RI+ K+ + T+ NE
Sbjct: 1861 ERKMAEQYKEQAEKGNARVKQLKRQL-EEAEEESQRINANRRKLQRELDEA-TESNE 1915
Score = 35.5 bits (78), Expect = 0.46
Identities = 44/246 (17%), Positives = 108/246 (43%), Gaps = 20/246 (8%)
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
L E E++E +Q++ + EK+ + + + ++++ +++ D + K++K + LEE+
Sbjct: 955 LEEQLEEEEAARQKLQL--EKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDK 391
LT + + + N KL + +S++ ++ + +++S E++ K
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISEL--------EVRLKKEEKSRQELEKLKR---K 1059
Query: 392 ITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
+ + + QI + Q AQ+ E K Q+A E+ RL + L +I+
Sbjct: 1060 LEGDASDFHEQIADLQ----AQIA-ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR 1114
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ G ++ +L E+E +KT++ + ++ ++++
Sbjct: 1115 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Query: 512 ELKLGK 517
E+ + K
Sbjct: 1175 EVTVLK 1180
>BC101677-1|AAI01678.1| 1938|Homo sapiens myosin, heavy chain 11,
smooth muscle protein.
Length = 1938
Score = 65.3 bits (152), Expect = 5e-10
Identities = 88/457 (19%), Positives = 197/457 (43%), Gaps = 42/457 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E++ E + K+ + + +EL+ L++++ Q+ T + ++ E + + TE+ +
Sbjct: 852 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLLQEQLQAETEL-------Y 903
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE---TDINELRNSIKYLESVKSEYN 198
EE+ + + KK + + ++ L++ + + + ++ + LE E
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
A +KL + A K +++E+ ++ +N L + ++
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 259 NLEEMKTMLVEEKLSEIK---EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
NL ++K E +SE++ +K+E +QE++ L KL D +F+E + + +++L
Sbjct: 1024 NLTKLKNKH-ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1082
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF--------KIS 367
++ K E EL Q L L +++ +NN+ K I + +S + D K
Sbjct: 1083 MQLAKKEEEL---QAALARLDDEIAQ-KNNALKKIRELEGHISDLQEDLDSERAARNKAE 1138
Query: 368 NQ----------LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
Q L EL+D ++T + L K +T L ++E ++ AQ + E
Sbjct: 1139 KQKRDLGEELEALKTELEDTLDSTATQQELRA-KREQEVTVLKKALDEETRSHEAQ-VQE 1196
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
+++ A E+ L E+L Q + L QT+ N ++ L+
Sbjct: 1197 MRQKHAQAVEE---LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1253
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++++++K + + +L+D + + Q E++
Sbjct: 1254 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1290
Score = 50.4 bits (115), Expect = 1e-05
Identities = 81/441 (18%), Positives = 175/441 (39%), Gaps = 31/441 (7%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K E K ++ + +++L L +K+ + + + + ++ + L
Sbjct: 1247 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1306
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNIS-- 164
++ + +S + E++ T ++ LEE +L+ L + K N+
Sbjct: 1307 AKDVASL-SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1365
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNC 217
I TL +L + ++ + + ++++ LE K + E L +Q A DK +N
Sbjct: 1366 ISTLNIQL-SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424
Query: 218 IQEEVD--LLKIENQNLL---------QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+Q+E+D ++ ++NQ L + RD+ A E +T
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1484
Query: 267 LVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
+ L+ E+ K+E++ N+ L + + + + + +L K E ++E
Sbjct: 1485 ALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1542
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERIS 386
E + QL L ++L TE+ +L NM Q D + ++ + E + +
Sbjct: 1543 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYE 1602
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
L+ L + + D L +A I E+ I ++L +L+ + K+
Sbjct: 1603 TELEDERKQ-RALAAAAKKKLEGDLKDLELQADSAIKG-REEAI---KQLRKLQAQMKDF 1657
Query: 447 LIEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K++
Sbjct: 1658 QRELEDARASRDEIFATAKEN 1678
Score = 50.0 bits (114), Expect = 2e-05
Identities = 93/502 (18%), Positives = 199/502 (39%), Gaps = 41/502 (8%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTE 82
LEE +E + LQ + + +L+ DEI M Q L LT
Sbjct: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLE-DEILVMDDQNNKLSKERKLLEERISDLTT 1013
Query: 83 KLTIAETKHNDLKKL---YEDSASELEA-LKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L E K +L KL +E SELE LK+E ++ L +
Sbjct: 1014 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE---------LEKLKRKLEGDA 1064
Query: 139 NGF-ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ F E + ++ +I K + K ++ L +L + +I + N++K + ++
Sbjct: 1065 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARL----DDEIAQKNNALKKIRELEGHI 1120
Query: 198 NTANEKLFEQL---NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ E L + N A ++ + EE++ LK E ++ L
Sbjct: 1121 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1180
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE-KLICDRREFNETMQEKNILLSD 313
K + V+E + + E ++++ K D+ + +T++++N L+
Sbjct: 1181 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK--QTLEKENADLAG 1238
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ + + ++E+E K+++L +++L ++ + + +KV K+ N++
Sbjct: 1239 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH------KLQNEVESV 1292
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNII 431
+E + I L D + L++Q+ +TQ+ + + ++ L E+
Sbjct: 1293 TGMLNEAEGKAIKLAKD-----VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
L+++L + + L I T+ + L+D ++ EIE++ +
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1407
Query: 492 VMEWKSQFEDLDDVMKQQQKEL 513
E + ++ L+ + Q+EL
Sbjct: 1408 YEEKAAAYDKLEKTKNRLQQEL 1429
Score = 44.4 bits (100), Expect = 0.001
Identities = 78/424 (18%), Positives = 177/424 (41%), Gaps = 47/424 (11%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNI 163
E+ LK+ + S V E+ + + LT E + +D K ++ K+N
Sbjct: 1175 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1234
Query: 164 SIKTLLDKLITKNETDINELRNSIK-YLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEE 221
+ L +++ + + ++ + ++ ++ ++S+ + E+ +LN+ V K QN ++
Sbjct: 1235 DLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESV 1292
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN 281
+L N + + + E + + V KL +++E+ +
Sbjct: 1293 TGML-----NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1347
Query: 282 FKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN---KTERELEEKQEQLTHLMEQ 338
+ ++D E ++ + NI LSD KK+ T LEE +++ +E
Sbjct: 1348 LQDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1403
Query: 339 LN---DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE--NTYERISLTLDKIT 393
L + + +Y +E N++ Q D + +LD++ + + E+ D++
Sbjct: 1404 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVV------DLDNQRQLVSNLEKKQRKFDQLL 1457
Query: 394 NHITYLNTQINETQKNDNAQLLWEAKK--QIADLTEQNIILKERLSQLETENKELLIEIQ 451
++++ + + A+ + K +A E+ + KE +LE NK L E++
Sbjct: 1458 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE---ELERTNKMLKAEME 1514
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ S ++V N+ + ++T++ E K+Q E+L+D + Q +
Sbjct: 1515 DLVSSKDDVGKNVHELEKSKRA--------------LETQMEEMKTQLEELEDEL-QATE 1559
Query: 512 ELKL 515
+ KL
Sbjct: 1560 DAKL 1563
Score = 41.5 bits (93), Expect = 0.007
Identities = 68/328 (20%), Positives = 135/328 (41%), Gaps = 30/328 (9%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + + N +K ++ L++ + +++EL S + LE+ E T E+
Sbjct: 1491 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1550
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + LK + + LQ R + L E
Sbjct: 1551 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEK---------RRQLQRQLHEY 1601
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+T L +E+ K E D+ + +L D + +E L L ++ +R
Sbjct: 1602 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--KGREEAIKQLRKLQAQMKDFQR 1659
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
ELE+ + + + E + L ++ +A+ + Q E ++ +E
Sbjct: 1660 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS 1719
Query: 384 RIS----LTLDK--ITNHITYLNTQINETQKN-----DNAQLLWEAKKQIAD--LTEQNI 430
+S L +K + I L ++ E Q N D + + +Q+++ TE++
Sbjct: 1720 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERST 1779
Query: 431 ILKERLS--QLETENKELLIEIQTVRGS 456
K + QLE +NKEL ++ + G+
Sbjct: 1780 AQKNESARQQLERQNKELRSKLHEMEGA 1807
Score = 37.9 bits (84), Expect = 0.085
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 252 ARDKFIANLEE--MKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQE 306
+RD+ A +E K +E L +++E E +++ D+ E+L E ++
Sbjct: 1667 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA---EELASSLSG 1723
Query: 307 KNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+N L + L ++ + E ELEE+Q + + +++ + +L + + S +
Sbjct: 1724 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1783
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
QL + + +E K + I L +I + ++ Q E +
Sbjct: 1784 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE-QEAREKQAATK 1842
Query: 424 DLTEQNIILKERLSQLETENK 444
L +++ LKE L Q+E E K
Sbjct: 1843 SLKQKDKKLKEILLQVEDERK 1863
Score = 36.7 bits (81), Expect = 0.20
Identities = 43/237 (18%), Positives = 98/237 (41%), Gaps = 15/237 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E D+ +L+ + E + + + E+L E+L +++ +N +Q+E L+ + Q
Sbjct: 1686 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE---ARIAQLE 1742
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICD 296
K E++ L E+ +K+E+ +Q+++ N++L
Sbjct: 1743 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATER--STAQKNESARQQLERQNKELRSK 1800
Query: 297 RREFNETMQEK-NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKL---IEN 352
E ++ K ++ L K+ + E ++E++ + + L + ++ +E+
Sbjct: 1801 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1860
Query: 353 MFNKVSQIASDFKISN----QLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
Q + N QL +L +E+E +RI+ K+ + T+ NE
Sbjct: 1861 ERKMAEQYKEQAEKGNARVKQLKRQL-EEAEEESQRINANRRKLQRELDEA-TESNE 1915
Score = 35.5 bits (78), Expect = 0.46
Identities = 44/246 (17%), Positives = 108/246 (43%), Gaps = 20/246 (8%)
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
L E E++E +Q++ + EK+ + + + ++++ +++ D + K++K + LEE+
Sbjct: 955 LEEQLEEEEAARQKLQL--EKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISD 1010
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDK 391
LT + + + N KL + +S++ ++ + +++S E++ K
Sbjct: 1011 LTTNLAEEEEKAKNLTKLKNKHESMISEL--------EVRLKKEEKSRQELEKLKR---K 1059
Query: 392 ITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
+ + + QI + Q AQ+ E K Q+A E+ RL + L +I+
Sbjct: 1060 LEGDASDFHEQIADLQ----AQIA-ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR 1114
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ G ++ +L E+E +KT++ + ++ ++++
Sbjct: 1115 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1174
Query: 512 ELKLGK 517
E+ + K
Sbjct: 1175 EVTVLK 1180
>AY520817-1|AAS98911.1| 1945|Homo sapiens smooth muscle myosin heavy
chain isoform SM2 protein.
Length = 1945
Score = 65.3 bits (152), Expect = 5e-10
Identities = 88/457 (19%), Positives = 197/457 (43%), Gaps = 42/457 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E++ E + K+ + + +EL+ L++++ Q+ T + ++ E + + TE+ +
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLLQEQLQAETEL-------Y 910
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE---TDINELRNSIKYLESVKSEYN 198
EE+ + + KK + + ++ L++ + + + ++ + LE E
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
A +KL + A K +++E+ ++ +N L + ++
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 259 NLEEMKTMLVEEKLSEIK---EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
NL ++K E +SE++ +K+E +QE++ L KL D +F+E + + +++L
Sbjct: 1031 NLTKLKNKH-ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1089
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF--------KIS 367
++ K E EL Q L L +++ +NN+ K I + +S + D K
Sbjct: 1090 MQLAKKEEEL---QAALARLDDEIAQ-KNNALKKIRELEGHISDLQEDLDSERAARNKAE 1145
Query: 368 NQ----------LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
Q L EL+D ++T + L K +T L ++E ++ AQ + E
Sbjct: 1146 KQKRDLGEELEALKTELEDTLDSTATQQELRA-KREQEVTVLKKALDEETRSHEAQ-VQE 1203
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
+++ A E+ L E+L Q + L QT+ N ++ L+
Sbjct: 1204 MRQKHAQAVEE---LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1260
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++++++K + + +L+D + + Q E++
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1297
Score = 50.4 bits (115), Expect = 1e-05
Identities = 81/441 (18%), Positives = 175/441 (39%), Gaps = 31/441 (7%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K E K ++ + +++L L +K+ + + + + ++ + L
Sbjct: 1254 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1313
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNIS-- 164
++ + +S + E++ T ++ LEE +L+ L + K N+
Sbjct: 1314 AKDVASL-SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNC 217
I TL +L + ++ + + ++++ LE K + E L +Q A DK +N
Sbjct: 1373 ISTLNIQL-SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431
Query: 218 IQEEVD--LLKIENQNLL---------QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+Q+E+D ++ ++NQ L + RD+ A E +T
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1491
Query: 267 LVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
+ L+ E+ K+E++ N+ L + + + + + +L K E ++E
Sbjct: 1492 ALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1549
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERIS 386
E + QL L ++L TE+ +L NM Q D + ++ + E + +
Sbjct: 1550 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYE 1609
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
L+ L + + D L +A I E+ I ++L +L+ + K+
Sbjct: 1610 TELEDERKQ-RALAAAAKKKLEGDLKDLELQADSAIKG-REEAI---KQLRKLQAQMKDF 1664
Query: 447 LIEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K++
Sbjct: 1665 QRELEDARASRDEIFATAKEN 1685
Score = 50.0 bits (114), Expect = 2e-05
Identities = 93/502 (18%), Positives = 199/502 (39%), Gaps = 41/502 (8%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTE 82
LEE +E + LQ + + +L+ DEI M Q L LT
Sbjct: 962 LEEQLEEEEAARQKLQLEKVTAEAKIKKLE-DEILVMDDQNNKLSKERKLLEERISDLTT 1020
Query: 83 KLTIAETKHNDLKKL---YEDSASELEA-LKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L E K +L KL +E SELE LK+E ++ L +
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE---------LEKLKRKLEGDA 1071
Query: 139 NGF-ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ F E + ++ +I K + K ++ L +L + +I + N++K + ++
Sbjct: 1072 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARL----DDEIAQKNNALKKIRELEGHI 1127
Query: 198 NTANEKLFEQL---NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ E L + N A ++ + EE++ LK E ++ L
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1187
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE-KLICDRREFNETMQEKNILLSD 313
K + V+E + + E ++++ K D+ + +T++++N L+
Sbjct: 1188 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK--QTLEKENADLAG 1245
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ + + ++E+E K+++L +++L ++ + + +KV K+ N++
Sbjct: 1246 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH------KLQNEVESV 1299
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNII 431
+E + I L D + L++Q+ +TQ+ + + ++ L E+
Sbjct: 1300 TGMLNEAEGKAIKLAKD-----VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
L+++L + + L I T+ + L+D ++ EIE++ +
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414
Query: 492 VMEWKSQFEDLDDVMKQQQKEL 513
E + ++ L+ + Q+EL
Sbjct: 1415 YEEKAAAYDKLEKTKNRLQQEL 1436
Score = 44.4 bits (100), Expect = 0.001
Identities = 78/424 (18%), Positives = 177/424 (41%), Gaps = 47/424 (11%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNI 163
E+ LK+ + S V E+ + + LT E + +D K ++ K+N
Sbjct: 1182 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1241
Query: 164 SIKTLLDKLITKNETDINELRNSIK-YLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEE 221
+ L +++ + + ++ + ++ ++ ++S+ + E+ +LN+ V K QN ++
Sbjct: 1242 DLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESV 1299
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN 281
+L N + + + E + + V KL +++E+ +
Sbjct: 1300 TGML-----NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 282 FKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN---KTERELEEKQEQLTHLMEQ 338
+ ++D E ++ + NI LSD KK+ T LEE +++ +E
Sbjct: 1355 LQDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1410
Query: 339 LN---DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE--NTYERISLTLDKIT 393
L + + +Y +E N++ Q D + +LD++ + + E+ D++
Sbjct: 1411 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVV------DLDNQRQLVSNLEKKQRKFDQLL 1464
Query: 394 NHITYLNTQINETQKNDNAQLLWEAKK--QIADLTEQNIILKERLSQLETENKELLIEIQ 451
++++ + + A+ + K +A E+ + KE +LE NK L E++
Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE---ELERTNKMLKAEME 1521
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ S ++V N+ + ++T++ E K+Q E+L+D + Q +
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRA--------------LETQMEEMKTQLEELEDEL-QATE 1566
Query: 512 ELKL 515
+ KL
Sbjct: 1567 DAKL 1570
Score = 41.5 bits (93), Expect = 0.007
Identities = 68/328 (20%), Positives = 135/328 (41%), Gaps = 30/328 (9%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + + N +K ++ L++ + +++EL S + LE+ E T E+
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1557
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + LK + + LQ R + L E
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEK---------RRQLQRQLHEY 1608
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+T L +E+ K E D+ + +L D + +E L L ++ +R
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--KGREEAIKQLRKLQAQMKDFQR 1666
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
ELE+ + + + E + L ++ +A+ + Q E ++ +E
Sbjct: 1667 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS 1726
Query: 384 RIS----LTLDK--ITNHITYLNTQINETQKN-----DNAQLLWEAKKQIAD--LTEQNI 430
+S L +K + I L ++ E Q N D + + +Q+++ TE++
Sbjct: 1727 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERST 1786
Query: 431 ILKERLS--QLETENKELLIEIQTVRGS 456
K + QLE +NKEL ++ + G+
Sbjct: 1787 AQKNESARQQLERQNKELRSKLHEMEGA 1814
Score = 37.9 bits (84), Expect = 0.085
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 252 ARDKFIANLEE--MKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQE 306
+RD+ A +E K +E L +++E E +++ D+ E+L E ++
Sbjct: 1674 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA---EELASSLSG 1730
Query: 307 KNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+N L + L ++ + E ELEE+Q + + +++ + +L + + S +
Sbjct: 1731 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1790
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
QL + + +E K + I L +I + ++ Q E +
Sbjct: 1791 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE-QEAREKQAATK 1849
Query: 424 DLTEQNIILKERLSQLETENK 444
L +++ LKE L Q+E E K
Sbjct: 1850 SLKQKDKKLKEILLQVEDERK 1870
Score = 36.7 bits (81), Expect = 0.20
Identities = 43/237 (18%), Positives = 98/237 (41%), Gaps = 15/237 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E D+ +L+ + E + + + E+L E+L +++ +N +Q+E L+ + Q
Sbjct: 1693 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE---ARIAQLE 1749
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICD 296
K E++ L E+ +K+E+ +Q+++ N++L
Sbjct: 1750 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATER--STAQKNESARQQLERQNKELRSK 1807
Query: 297 RREFNETMQEK-NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKL---IEN 352
E ++ K ++ L K+ + E ++E++ + + L + ++ +E+
Sbjct: 1808 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1867
Query: 353 MFNKVSQIASDFKISN----QLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
Q + N QL +L +E+E +RI+ K+ + T+ NE
Sbjct: 1868 ERKMAEQYKEQAEKGNARVKQLKRQL-EEAEEESQRINANRRKLQRELDEA-TESNE 1922
Score = 35.5 bits (78), Expect = 0.46
Identities = 44/246 (17%), Positives = 108/246 (43%), Gaps = 20/246 (8%)
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
L E E++E +Q++ + EK+ + + + ++++ +++ D + K++K + LEE+
Sbjct: 962 LEEQLEEEEAARQKLQL--EKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDK 391
LT + + + N KL + +S++ ++ + +++S E++ K
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISEL--------EVRLKKEEKSRQELEKLKR---K 1066
Query: 392 ITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
+ + + QI + Q AQ+ E K Q+A E+ RL + L +I+
Sbjct: 1067 LEGDASDFHEQIADLQ----AQIA-ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR 1121
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ G ++ +L E+E +KT++ + ++ ++++
Sbjct: 1122 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1181
Query: 512 ELKLGK 517
E+ + K
Sbjct: 1182 EVTVLK 1187
>AY520816-1|AAS98910.1| 1979|Homo sapiens smooth muscle myosin heavy
chain isoform SM1 protein.
Length = 1979
Score = 65.3 bits (152), Expect = 5e-10
Identities = 88/457 (19%), Positives = 197/457 (43%), Gaps = 42/457 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E++ E + K+ + + +EL+ L++++ Q+ T + ++ E + + TE+ +
Sbjct: 859 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLLQEQLQAETEL-------Y 910
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE---TDINELRNSIKYLESVKSEYN 198
EE+ + + KK + + ++ L++ + + + ++ + LE E
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
A +KL + A K +++E+ ++ +N L + ++
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 259 NLEEMKTMLVEEKLSEIK---EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
NL ++K E +SE++ +K+E +QE++ L KL D +F+E + + +++L
Sbjct: 1031 NLTKLKNKH-ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1089
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF--------KIS 367
++ K E EL Q L L +++ +NN+ K I + +S + D K
Sbjct: 1090 MQLAKKEEEL---QAALARLDDEIAQ-KNNALKKIRELEGHISDLQEDLDSERAARNKAE 1145
Query: 368 NQ----------LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
Q L EL+D ++T + L K +T L ++E ++ AQ + E
Sbjct: 1146 KQKRDLGEELEALKTELEDTLDSTATQQELRA-KREQEVTVLKKALDEETRSHEAQ-VQE 1203
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
+++ A E+ L E+L Q + L QT+ N ++ L+
Sbjct: 1204 MRQKHAQAVEE---LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1260
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++++++K + + +L+D + + Q E++
Sbjct: 1261 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1297
Score = 50.4 bits (115), Expect = 1e-05
Identities = 81/441 (18%), Positives = 175/441 (39%), Gaps = 31/441 (7%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K E K ++ + +++L L +K+ + + + + ++ + L
Sbjct: 1254 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1313
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNIS-- 164
++ + +S + E++ T ++ LEE +L+ L + K N+
Sbjct: 1314 AKDVASL-SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1372
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNC 217
I TL +L + ++ + + ++++ LE K + E L +Q A DK +N
Sbjct: 1373 ISTLNIQL-SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431
Query: 218 IQEEVD--LLKIENQNLL---------QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+Q+E+D ++ ++NQ L + RD+ A E +T
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1491
Query: 267 LVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
+ L+ E+ K+E++ N+ L + + + + + +L K E ++E
Sbjct: 1492 ALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1549
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERIS 386
E + QL L ++L TE+ +L NM Q D + ++ + E + +
Sbjct: 1550 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYE 1609
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
L+ L + + D L +A I E+ I ++L +L+ + K+
Sbjct: 1610 TELEDERKQ-RALAAAAKKKLEGDLKDLELQADSAIKG-REEAI---KQLRKLQAQMKDF 1664
Query: 447 LIEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K++
Sbjct: 1665 QRELEDARASRDEIFATAKEN 1685
Score = 50.0 bits (114), Expect = 2e-05
Identities = 93/502 (18%), Positives = 199/502 (39%), Gaps = 41/502 (8%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTE 82
LEE +E + LQ + + +L+ DEI M Q L LT
Sbjct: 962 LEEQLEEEEAARQKLQLEKVTAEAKIKKLE-DEILVMDDQNNKLSKERKLLEERISDLTT 1020
Query: 83 KLTIAETKHNDLKKL---YEDSASELEA-LKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L E K +L KL +E SELE LK+E ++ L +
Sbjct: 1021 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE---------LEKLKRKLEGDA 1071
Query: 139 NGF-ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ F E + ++ +I K + K ++ L +L + +I + N++K + ++
Sbjct: 1072 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARL----DDEIAQKNNALKKIRELEGHI 1127
Query: 198 NTANEKLFEQL---NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ E L + N A ++ + EE++ LK E ++ L
Sbjct: 1128 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1187
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE-KLICDRREFNETMQEKNILLSD 313
K + V+E + + E ++++ K D+ + +T++++N L+
Sbjct: 1188 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK--QTLEKENADLAG 1245
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ + + ++E+E K+++L +++L ++ + + +KV K+ N++
Sbjct: 1246 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH------KLQNEVESV 1299
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNII 431
+E + I L D + L++Q+ +TQ+ + + ++ L E+
Sbjct: 1300 TGMLNEAEGKAIKLAKD-----VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
L+++L + + L I T+ + L+D ++ EIE++ +
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1414
Query: 492 VMEWKSQFEDLDDVMKQQQKEL 513
E + ++ L+ + Q+EL
Sbjct: 1415 YEEKAAAYDKLEKTKNRLQQEL 1436
Score = 44.4 bits (100), Expect = 0.001
Identities = 78/424 (18%), Positives = 177/424 (41%), Gaps = 47/424 (11%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNI 163
E+ LK+ + S V E+ + + LT E + +D K ++ K+N
Sbjct: 1182 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1241
Query: 164 SIKTLLDKLITKNETDINELRNSIK-YLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEE 221
+ L +++ + + ++ + ++ ++ ++S+ + E+ +LN+ V K QN ++
Sbjct: 1242 DLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESV 1299
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN 281
+L N + + + E + + V KL +++E+ +
Sbjct: 1300 TGML-----NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1354
Query: 282 FKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN---KTERELEEKQEQLTHLMEQ 338
+ ++D E ++ + NI LSD KK+ T LEE +++ +E
Sbjct: 1355 LQDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1410
Query: 339 LN---DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE--NTYERISLTLDKIT 393
L + + +Y +E N++ Q D + +LD++ + + E+ D++
Sbjct: 1411 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVV------DLDNQRQLVSNLEKKQRKFDQLL 1464
Query: 394 NHITYLNTQINETQKNDNAQLLWEAKK--QIADLTEQNIILKERLSQLETENKELLIEIQ 451
++++ + + A+ + K +A E+ + KE +LE NK L E++
Sbjct: 1465 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE---ELERTNKMLKAEME 1521
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ S ++V N+ + ++T++ E K+Q E+L+D + Q +
Sbjct: 1522 DLVSSKDDVGKNVHELEKSKRA--------------LETQMEEMKTQLEELEDEL-QATE 1566
Query: 512 ELKL 515
+ KL
Sbjct: 1567 DAKL 1570
Score = 41.5 bits (93), Expect = 0.007
Identities = 68/328 (20%), Positives = 135/328 (41%), Gaps = 30/328 (9%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + + N +K ++ L++ + +++EL S + LE+ E T E+
Sbjct: 1498 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1557
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + LK + + LQ R + L E
Sbjct: 1558 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEK---------RRQLQRQLHEY 1608
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+T L +E+ K E D+ + +L D + +E L L ++ +R
Sbjct: 1609 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--KGREEAIKQLRKLQAQMKDFQR 1666
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
ELE+ + + + E + L ++ +A+ + Q E ++ +E
Sbjct: 1667 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS 1726
Query: 384 RIS----LTLDK--ITNHITYLNTQINETQKN-----DNAQLLWEAKKQIAD--LTEQNI 430
+S L +K + I L ++ E Q N D + + +Q+++ TE++
Sbjct: 1727 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERST 1786
Query: 431 ILKERLS--QLETENKELLIEIQTVRGS 456
K + QLE +NKEL ++ + G+
Sbjct: 1787 AQKNESARQQLERQNKELRSKLHEMEGA 1814
Score = 37.9 bits (84), Expect = 0.085
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 252 ARDKFIANLEE--MKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQE 306
+RD+ A +E K +E L +++E E +++ D+ E+L E ++
Sbjct: 1674 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA---EELASSLSG 1730
Query: 307 KNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+N L + L ++ + E ELEE+Q + + +++ + +L + + S +
Sbjct: 1731 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1790
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
QL + + +E K + I L +I + ++ Q E +
Sbjct: 1791 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE-QEAREKQAATK 1849
Query: 424 DLTEQNIILKERLSQLETENK 444
L +++ LKE L Q+E E K
Sbjct: 1850 SLKQKDKKLKEILLQVEDERK 1870
Score = 36.7 bits (81), Expect = 0.20
Identities = 43/237 (18%), Positives = 98/237 (41%), Gaps = 15/237 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E D+ +L+ + E + + + E+L E+L +++ +N +Q+E L+ + Q
Sbjct: 1693 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE---ARIAQLE 1749
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICD 296
K E++ L E+ +K+E+ +Q+++ N++L
Sbjct: 1750 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATER--STAQKNESARQQLERQNKELRSK 1807
Query: 297 RREFNETMQEK-NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKL---IEN 352
E ++ K ++ L K+ + E ++E++ + + L + ++ +E+
Sbjct: 1808 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1867
Query: 353 MFNKVSQIASDFKISN----QLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
Q + N QL +L +E+E +RI+ K+ + T+ NE
Sbjct: 1868 ERKMAEQYKEQAEKGNARVKQLKRQL-EEAEEESQRINANRRKLQRELDEA-TESNE 1922
Score = 35.5 bits (78), Expect = 0.46
Identities = 44/246 (17%), Positives = 108/246 (43%), Gaps = 20/246 (8%)
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
L E E++E +Q++ + EK+ + + + ++++ +++ D + K++K + LEE+
Sbjct: 962 LEEQLEEEEAARQKLQL--EKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISD 1017
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDK 391
LT + + + N KL + +S++ ++ + +++S E++ K
Sbjct: 1018 LTTNLAEEEEKAKNLTKLKNKHESMISEL--------EVRLKKEEKSRQELEKLKR---K 1066
Query: 392 ITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
+ + + QI + Q AQ+ E K Q+A E+ RL + L +I+
Sbjct: 1067 LEGDASDFHEQIADLQ----AQIA-ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR 1121
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ G ++ +L E+E +KT++ + ++ ++++
Sbjct: 1122 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1181
Query: 512 ELKLGK 517
E+ + K
Sbjct: 1182 EVTVLK 1187
>AF001548-1|AAC31665.1| 1857|Homo sapiens Myosin heavy chain (MHY11)
(5'partial) protein.
Length = 1857
Score = 65.3 bits (152), Expect = 5e-10
Identities = 88/457 (19%), Positives = 197/457 (43%), Gaps = 42/457 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E++ E + K+ + + +EL+ L++++ Q+ T + ++ E + + TE+ +
Sbjct: 737 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLLQEQLQAETEL-------Y 788
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE---TDINELRNSIKYLESVKSEYN 198
EE+ + + KK + + ++ L++ + + + ++ + LE E
Sbjct: 789 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 848
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
A +KL + A K +++E+ ++ +N L + ++
Sbjct: 849 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 908
Query: 259 NLEEMKTMLVEEKLSEIK---EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
NL ++K E +SE++ +K+E +QE++ L KL D +F+E + + +++L
Sbjct: 909 NLTKLKNKH-ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 967
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF--------KIS 367
++ K E EL Q L L +++ +NN+ K I + +S + D K
Sbjct: 968 MQLAKKEEEL---QAALARLDDEIAQ-KNNALKKIRELEGHISDLQEDLDSERAARNKAE 1023
Query: 368 NQ----------LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
Q L EL+D ++T + L K +T L ++E ++ AQ + E
Sbjct: 1024 KQKRDLGEELEALKTELEDTLDSTATQQELRA-KREQEVTVLKKALDEETRSHEAQ-VQE 1081
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
+++ A E+ L E+L Q + L QT+ N ++ L+
Sbjct: 1082 MRQKHAQAVEE---LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1138
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++++++K + + +L+D + + Q E++
Sbjct: 1139 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1175
Score = 50.4 bits (115), Expect = 1e-05
Identities = 81/441 (18%), Positives = 175/441 (39%), Gaps = 31/441 (7%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K E K ++ + +++L L +K+ + + + + ++ + L
Sbjct: 1132 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1191
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNIS-- 164
++ + +S + E++ T ++ LEE +L+ L + K N+
Sbjct: 1192 AKDVASL-SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1250
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNC 217
I TL +L + ++ + + ++++ LE K + E L +Q A DK +N
Sbjct: 1251 ISTLNIQL-SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1309
Query: 218 IQEEVD--LLKIENQNLL---------QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+Q+E+D ++ ++NQ L + RD+ A E +T
Sbjct: 1310 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1369
Query: 267 LVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
+ L+ E+ K+E++ N+ L + + + + + +L K E ++E
Sbjct: 1370 ALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1427
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERIS 386
E + QL L ++L TE+ +L NM Q D + ++ + E + +
Sbjct: 1428 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYE 1487
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
L+ L + + D L +A I E+ I ++L +L+ + K+
Sbjct: 1488 TELEDERKQ-RALAAAAKKKLEGDLKDLELQADSAIKG-REEAI---KQLRKLQAQMKDF 1542
Query: 447 LIEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K++
Sbjct: 1543 QRELEDARASRDEIFATAKEN 1563
Score = 50.0 bits (114), Expect = 2e-05
Identities = 93/502 (18%), Positives = 199/502 (39%), Gaps = 41/502 (8%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTE 82
LEE +E + LQ + + +L+ DEI M Q L LT
Sbjct: 840 LEEQLEEEEAARQKLQLEKVTAEAKIKKLE-DEILVMDDQNNKLSKERKLLEERISDLTT 898
Query: 83 KLTIAETKHNDLKKL---YEDSASELEA-LKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L E K +L KL +E SELE LK+E ++ L +
Sbjct: 899 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE---------LEKLKRKLEGDA 949
Query: 139 NGF-ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ F E + ++ +I K + K ++ L +L + +I + N++K + ++
Sbjct: 950 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARL----DDEIAQKNNALKKIRELEGHI 1005
Query: 198 NTANEKLFEQL---NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ E L + N A ++ + EE++ LK E ++ L
Sbjct: 1006 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1065
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE-KLICDRREFNETMQEKNILLSD 313
K + V+E + + E ++++ K D+ + +T++++N L+
Sbjct: 1066 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK--QTLEKENADLAG 1123
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ + + ++E+E K+++L +++L ++ + + +KV K+ N++
Sbjct: 1124 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH------KLQNEVESV 1177
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNII 431
+E + I L D + L++Q+ +TQ+ + + ++ L E+
Sbjct: 1178 TGMLNEAEGKAIKLAKD-----VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1232
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
L+++L + + L I T+ + L+D ++ EIE++ +
Sbjct: 1233 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1292
Query: 492 VMEWKSQFEDLDDVMKQQQKEL 513
E + ++ L+ + Q+EL
Sbjct: 1293 YEEKAAAYDKLEKTKNRLQQEL 1314
Score = 44.4 bits (100), Expect = 0.001
Identities = 78/424 (18%), Positives = 177/424 (41%), Gaps = 47/424 (11%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNI 163
E+ LK+ + S V E+ + + LT E + +D K ++ K+N
Sbjct: 1060 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1119
Query: 164 SIKTLLDKLITKNETDINELRNSIK-YLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEE 221
+ L +++ + + ++ + ++ ++ ++S+ + E+ +LN+ V K QN ++
Sbjct: 1120 DLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESV 1177
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN 281
+L N + + + E + + V KL +++E+ +
Sbjct: 1178 TGML-----NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1232
Query: 282 FKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN---KTERELEEKQEQLTHLMEQ 338
+ ++D E ++ + NI LSD KK+ T LEE +++ +E
Sbjct: 1233 LQDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1288
Query: 339 LN---DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE--NTYERISLTLDKIT 393
L + + +Y +E N++ Q D + +LD++ + + E+ D++
Sbjct: 1289 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVV------DLDNQRQLVSNLEKKQRKFDQLL 1342
Query: 394 NHITYLNTQINETQKNDNAQLLWEAKK--QIADLTEQNIILKERLSQLETENKELLIEIQ 451
++++ + + A+ + K +A E+ + KE +LE NK L E++
Sbjct: 1343 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE---ELERTNKMLKAEME 1399
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ S ++V N+ + ++T++ E K+Q E+L+D + Q +
Sbjct: 1400 DLVSSKDDVGKNVHELEKSKRA--------------LETQMEEMKTQLEELEDEL-QATE 1444
Query: 512 ELKL 515
+ KL
Sbjct: 1445 DAKL 1448
Score = 41.5 bits (93), Expect = 0.007
Identities = 68/328 (20%), Positives = 135/328 (41%), Gaps = 30/328 (9%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + + N +K ++ L++ + +++EL S + LE+ E T E+
Sbjct: 1376 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1435
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + LK + + LQ R + L E
Sbjct: 1436 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEK---------RRQLQRQLHEY 1486
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+T L +E+ K E D+ + +L D + +E L L ++ +R
Sbjct: 1487 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--KGREEAIKQLRKLQAQMKDFQR 1544
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
ELE+ + + + E + L ++ +A+ + Q E ++ +E
Sbjct: 1545 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS 1604
Query: 384 RIS----LTLDK--ITNHITYLNTQINETQKN-----DNAQLLWEAKKQIAD--LTEQNI 430
+S L +K + I L ++ E Q N D + + +Q+++ TE++
Sbjct: 1605 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERST 1664
Query: 431 ILKERLS--QLETENKELLIEIQTVRGS 456
K + QLE +NKEL ++ + G+
Sbjct: 1665 AQKNESARQQLERQNKELRSKLHEMEGA 1692
Score = 37.9 bits (84), Expect = 0.085
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 252 ARDKFIANLEE--MKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQE 306
+RD+ A +E K +E L +++E E +++ D+ E+L E ++
Sbjct: 1552 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA---EELASSLSG 1608
Query: 307 KNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+N L + L ++ + E ELEE+Q + + +++ + +L + + S +
Sbjct: 1609 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1668
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
QL + + +E K + I L +I + ++ Q E +
Sbjct: 1669 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE-QEAREKQAATK 1727
Query: 424 DLTEQNIILKERLSQLETENK 444
L +++ LKE L Q+E E K
Sbjct: 1728 SLKQKDKKLKEILLQVEDERK 1748
Score = 36.7 bits (81), Expect = 0.20
Identities = 43/237 (18%), Positives = 98/237 (41%), Gaps = 15/237 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E D+ +L+ + E + + + E+L E+L +++ +N +Q+E L+ + Q
Sbjct: 1571 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE---ARIAQLE 1627
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICD 296
K E++ L E+ +K+E+ +Q+++ N++L
Sbjct: 1628 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATER--STAQKNESARQQLERQNKELRSK 1685
Query: 297 RREFNETMQEK-NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKL---IEN 352
E ++ K ++ L K+ + E ++E++ + + L + ++ +E+
Sbjct: 1686 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1745
Query: 353 MFNKVSQIASDFKISN----QLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
Q + N QL +L +E+E +RI+ K+ + T+ NE
Sbjct: 1746 ERKMAEQYKEQAEKGNARVKQLKRQL-EEAEEESQRINANRRKLQRELDEA-TESNE 1800
Score = 35.5 bits (78), Expect = 0.46
Identities = 44/246 (17%), Positives = 108/246 (43%), Gaps = 20/246 (8%)
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
L E E++E +Q++ + EK+ + + + ++++ +++ D + K++K + LEE+
Sbjct: 840 LEEQLEEEEAARQKLQL--EKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISD 895
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDK 391
LT + + + N KL + +S++ ++ + +++S E++ K
Sbjct: 896 LTTNLAEEEEKAKNLTKLKNKHESMISEL--------EVRLKKEEKSRQELEKLKR---K 944
Query: 392 ITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
+ + + QI + Q AQ+ E K Q+A E+ RL + L +I+
Sbjct: 945 LEGDASDFHEQIADLQ----AQIA-ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR 999
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ G ++ +L E+E +KT++ + ++ ++++
Sbjct: 1000 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1059
Query: 512 ELKLGK 517
E+ + K
Sbjct: 1060 EVTVLK 1065
>AB020673-1|BAA74889.2| 1984|Homo sapiens KIAA0866 protein protein.
Length = 1984
Score = 65.3 bits (152), Expect = 5e-10
Identities = 88/457 (19%), Positives = 197/457 (43%), Gaps = 42/457 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E++ E + K+ + + +EL+ L++++ Q+ T + ++ E + + TE+ +
Sbjct: 864 EEMQAKEDELQKTKERQQKAENELKELEQKHSQL-TEEKNLLQEQLQAETEL-------Y 915
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE---TDINELRNSIKYLESVKSEYN 198
EE+ + + KK + + ++ L++ + + + ++ + LE E
Sbjct: 916 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 975
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
A +KL + A K +++E+ ++ +N L + ++
Sbjct: 976 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1035
Query: 259 NLEEMKTMLVEEKLSEIK---EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
NL ++K E +SE++ +K+E +QE++ L KL D +F+E + + +++L
Sbjct: 1036 NLTKLKNKH-ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELK 1094
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF--------KIS 367
++ K E EL Q L L +++ +NN+ K I + +S + D K
Sbjct: 1095 MQLAKKEEEL---QAALARLDDEIAQ-KNNALKKIRELEGHISDLQEDLDSERAARNKAE 1150
Query: 368 NQ----------LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
Q L EL+D ++T + L K +T L ++E ++ AQ + E
Sbjct: 1151 KQKRDLGEELEALKTELEDTLDSTATQQELRA-KREQEVTVLKKALDEETRSHEAQ-VQE 1208
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
+++ A E+ L E+L Q + L QT+ N ++ L+
Sbjct: 1209 MRQKHAQAVEE---LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHK 1265
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++++++K + + +L+D + + Q E++
Sbjct: 1266 KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 1302
Score = 50.4 bits (115), Expect = 1e-05
Identities = 81/441 (18%), Positives = 175/441 (39%), Gaps = 31/441 (7%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K E K ++ + +++L L +K+ + + + + ++ + L
Sbjct: 1259 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 1318
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNIS-- 164
++ + +S + E++ T ++ LEE +L+ L + K N+
Sbjct: 1319 AKDVASL-SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 1377
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNC 217
I TL +L + ++ + + ++++ LE K + E L +Q A DK +N
Sbjct: 1378 ISTLNIQL-SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1436
Query: 218 IQEEVD--LLKIENQNLL---------QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+Q+E+D ++ ++NQ L + RD+ A E +T
Sbjct: 1437 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1496
Query: 267 LVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
+ L+ E+ K+E++ N+ L + + + + + +L K E ++E
Sbjct: 1497 ALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 1554
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERIS 386
E + QL L ++L TE+ +L NM Q D + ++ + E + +
Sbjct: 1555 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYE 1614
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
L+ L + + D L +A I E+ I ++L +L+ + K+
Sbjct: 1615 TELEDERKQ-RALAAAAKKKLEGDLKDLELQADSAIKG-REEAI---KQLRKLQAQMKDF 1669
Query: 447 LIEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K++
Sbjct: 1670 QRELEDARASRDEIFATAKEN 1690
Score = 50.0 bits (114), Expect = 2e-05
Identities = 93/502 (18%), Positives = 199/502 (39%), Gaps = 41/502 (8%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTE 82
LEE +E + LQ + + +L+ DEI M Q L LT
Sbjct: 967 LEEQLEEEEAARQKLQLEKVTAEAKIKKLE-DEILVMDDQNNKLSKERKLLEERISDLTT 1025
Query: 83 KLTIAETKHNDLKKL---YEDSASELEA-LKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L E K +L KL +E SELE LK+E ++ L +
Sbjct: 1026 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE---------LEKLKRKLEGDA 1076
Query: 139 NGF-ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ F E + ++ +I K + K ++ L +L + +I + N++K + ++
Sbjct: 1077 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARL----DDEIAQKNNALKKIRELEGHI 1132
Query: 198 NTANEKLFEQL---NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ E L + N A ++ + EE++ LK E ++ L
Sbjct: 1133 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 1192
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE-KLICDRREFNETMQEKNILLSD 313
K + V+E + + E ++++ K D+ + +T++++N L+
Sbjct: 1193 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK--QTLEKENADLAG 1250
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ + + ++E+E K+++L +++L ++ + + +KV K+ N++
Sbjct: 1251 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH------KLQNEVESV 1304
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNII 431
+E + I L D + L++Q+ +TQ+ + + ++ L E+
Sbjct: 1305 TGMLNEAEGKAIKLAKD-----VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1359
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
L+++L + + L I T+ + L+D ++ EIE++ +
Sbjct: 1360 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 1419
Query: 492 VMEWKSQFEDLDDVMKQQQKEL 513
E + ++ L+ + Q+EL
Sbjct: 1420 YEEKAAAYDKLEKTKNRLQQEL 1441
Score = 44.4 bits (100), Expect = 0.001
Identities = 78/424 (18%), Positives = 177/424 (41%), Gaps = 47/424 (11%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNI 163
E+ LK+ + S V E+ + + LT E + +D K ++ K+N
Sbjct: 1187 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 1246
Query: 164 SIKTLLDKLITKNETDINELRNSIK-YLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEE 221
+ L +++ + + ++ + ++ ++ ++S+ + E+ +LN+ V K QN ++
Sbjct: 1247 DLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESV 1304
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN 281
+L N + + + E + + V KL +++E+ +
Sbjct: 1305 TGML-----NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 1359
Query: 282 FKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN---KTERELEEKQEQLTHLMEQ 338
+ ++D E ++ + NI LSD KK+ T LEE +++ +E
Sbjct: 1360 LQDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 1415
Query: 339 LN---DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE--NTYERISLTLDKIT 393
L + + +Y +E N++ Q D + +LD++ + + E+ D++
Sbjct: 1416 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVV------DLDNQRQLVSNLEKKQRKFDQLL 1469
Query: 394 NHITYLNTQINETQKNDNAQLLWEAKK--QIADLTEQNIILKERLSQLETENKELLIEIQ 451
++++ + + A+ + K +A E+ + KE +LE NK L E++
Sbjct: 1470 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE---ELERTNKMLKAEME 1526
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ S ++V N+ + ++T++ E K+Q E+L+D + Q +
Sbjct: 1527 DLVSSKDDVGKNVHELEKSKRA--------------LETQMEEMKTQLEELEDEL-QATE 1571
Query: 512 ELKL 515
+ KL
Sbjct: 1572 DAKL 1575
Score = 41.5 bits (93), Expect = 0.007
Identities = 68/328 (20%), Positives = 135/328 (41%), Gaps = 30/328 (9%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + + N +K ++ L++ + +++EL S + LE+ E T E+
Sbjct: 1503 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 1562
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + LK + + LQ R + L E
Sbjct: 1563 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEK---------RRQLQRQLHEY 1613
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+T L +E+ K E D+ + +L D + +E L L ++ +R
Sbjct: 1614 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--KGREEAIKQLRKLQAQMKDFQR 1671
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
ELE+ + + + E + L ++ +A+ + Q E ++ +E
Sbjct: 1672 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS 1731
Query: 384 RIS----LTLDK--ITNHITYLNTQINETQKN-----DNAQLLWEAKKQIAD--LTEQNI 430
+S L +K + I L ++ E Q N D + + +Q+++ TE++
Sbjct: 1732 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERST 1791
Query: 431 ILKERLS--QLETENKELLIEIQTVRGS 456
K + QLE +NKEL ++ + G+
Sbjct: 1792 AQKNESARQQLERQNKELRSKLHEMEGA 1819
Score = 37.9 bits (84), Expect = 0.085
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 252 ARDKFIANLEE--MKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQE 306
+RD+ A +E K +E L +++E E +++ D+ E+L E ++
Sbjct: 1679 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA---EELASSLSG 1735
Query: 307 KNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+N L + L ++ + E ELEE+Q + + +++ + +L + + S +
Sbjct: 1736 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 1795
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
QL + + +E K + I L +I + ++ Q E +
Sbjct: 1796 ESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE-QEAREKQAATK 1854
Query: 424 DLTEQNIILKERLSQLETENK 444
L +++ LKE L Q+E E K
Sbjct: 1855 SLKQKDKKLKEILLQVEDERK 1875
Score = 36.7 bits (81), Expect = 0.20
Identities = 43/237 (18%), Positives = 98/237 (41%), Gaps = 15/237 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E D+ +L+ + E + + + E+L E+L +++ +N +Q+E L+ + Q
Sbjct: 1698 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE---ARIAQLE 1754
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICD 296
K E++ L E+ +K+E+ +Q+++ N++L
Sbjct: 1755 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATER--STAQKNESARQQLERQNKELRSK 1812
Query: 297 RREFNETMQEK-NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKL---IEN 352
E ++ K ++ L K+ + E ++E++ + + L + ++ +E+
Sbjct: 1813 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 1872
Query: 353 MFNKVSQIASDFKISN----QLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
Q + N QL +L +E+E +RI+ K+ + T+ NE
Sbjct: 1873 ERKMAEQYKEQAEKGNARVKQLKRQL-EEAEEESQRINANRRKLQRELDEA-TESNE 1927
Score = 35.5 bits (78), Expect = 0.46
Identities = 44/246 (17%), Positives = 108/246 (43%), Gaps = 20/246 (8%)
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
L E E++E +Q++ + EK+ + + + ++++ +++ D + K++K + LEE+
Sbjct: 967 LEEQLEEEEAARQKLQL--EKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISD 1022
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDK 391
LT + + + N KL + +S++ ++ + +++S E++ K
Sbjct: 1023 LTTNLAEEEEKAKNLTKLKNKHESMISEL--------EVRLKKEEKSRQELEKLKR---K 1071
Query: 392 ITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
+ + + QI + Q AQ+ E K Q+A E+ RL + L +I+
Sbjct: 1072 LEGDASDFHEQIADLQ----AQIA-ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR 1126
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ G ++ +L E+E +KT++ + ++ ++++
Sbjct: 1127 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 1186
Query: 512 ELKLGK 517
E+ + K
Sbjct: 1187 EVTVLK 1192
>AL157400-6|CAI16830.1| 1820|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1820
Score = 64.5 bits (150), Expect = 9e-10
Identities = 95/508 (18%), Positives = 214/508 (42%), Gaps = 35/508 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETK 90
KE+ Q++S ++ + + V + KN E I +L ++ + TK
Sbjct: 931 KEVQQIQSNY--DIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTK 988
Query: 91 HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++L+ L DS S++ + N++ S+ + ++ +++ + ++E ++
Sbjct: 989 IDELRTL--DSVSQISNIDLLNLR-DLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQ 1045
Query: 151 IDLKKNSITKDNISIKTLLDKLI---TKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
++NS +I +++ +K I EL I+ L++ Y N +L E+
Sbjct: 1046 EPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK 1105
Query: 208 LNNAVD-----KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ D K+ IQ+ + L+ +N L + A ++E
Sbjct: 1106 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKE 1165
Query: 263 MKTMLVEEKLS-EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
++T+L +K+ K E E + + KL + +EF E +Q+ DL+ K K
Sbjct: 1166 LETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKL 1225
Query: 322 ERELEE---KQEQLTHLMEQLNDTENNSYKLIENMFNKVS-------QIASDFKISNQLS 371
+ E+ + + + HL++ + E + + E + ++S + +D + +
Sbjct: 1226 KEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDY 1285
Query: 372 CELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDN--AQLLWEAKKQIADLT 426
+L ++ + ++I +++ + L +INE +K N +Q L ++ I L
Sbjct: 1286 ADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLK 1345
Query: 427 EQ--NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNE 484
EQ N ++E + Q E K+L ++ + + E++ + L++ E
Sbjct: 1346 EQLNNQKVEEAIQQYERACKDLNVKEKII----EDMRMTLEEQEQTQVEQDQVLEAKLEE 1401
Query: 485 IEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+E + T++ +WK + DL+ Q+ +
Sbjct: 1402 VERLATELEKWKEKCNDLETKNNQRSNK 1429
Score = 53.2 bits (122), Expect = 2e-06
Identities = 85/437 (19%), Positives = 187/437 (42%), Gaps = 41/437 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMH-TSDVMV--VPEIIDSLTEVINTLT 138
E + E +H + L ++ + ++ LK E + + T DV + V E +L+E+ +T
Sbjct: 1098 ENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVT 1157
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDK--LITKNETDINELRNSIKYLESVKS- 195
++E+ ++ +K + + +L+K +I K E ++ E + ++ +SVK+
Sbjct: 1158 CYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQ--DSVKNT 1215
Query: 196 -EYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ N KL E++ N +Q+ LL+++ +
Sbjct: 1216 KDLNVKELKLKEEITQLT---NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQ 1272
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
A+L+ EE +++KEK + K++I + +K + R+ ++ ++ K +++L
Sbjct: 1273 NLKADLQRK-----EEDYADLKEKLTDAKKQIKQV-QKEVSVMRDEDKLLRIK---INEL 1323
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
KK N+ +EL+ KQ + L EQLN+ + +E + + D + ++ ++
Sbjct: 1324 EKKKNQCSQELDMKQRTIQQLKEQLNNQK------VEEAIQQYERACKDLNVKEKIIEDM 1377
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
E E+ + D++ L ++ E ++ W K++ DL +N +
Sbjct: 1378 RMTLEE-QEQTQVEQDQV------LEAKLEEVERLATELEKW--KEKCNDLETKN---NQ 1425
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
R ++ N ++L ++ ++ +E + E E+++ K E
Sbjct: 1426 RSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNK--E 1483
Query: 495 WKSQFEDLDDVMKQQQK 511
K ED + KQQ +
Sbjct: 1484 MKKYAEDRERFFKQQNE 1500
Score = 32.3 bits (70), Expect = 4.2
Identities = 65/350 (18%), Positives = 146/350 (41%), Gaps = 22/350 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTEKLTIA 87
+EI QL + LQ K + +LK +E + ++ L L L
Sbjct: 1227 EEITQLTNNLQDM-----KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1281
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E + DLK+ D+ +++ +++E M D ++ +I + L + N + + +
Sbjct: 1282 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI-NELEKKKNQCSQELDMKQRT 1340
Query: 148 ALEI-DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE 206
++ + N ++ I K + E I ++R +++ E + E + E E
Sbjct: 1341 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 1400
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM--- 263
++ + +E+ + +E +N + +D+ + ++
Sbjct: 1401 EVERLATELEKWKEKCN--DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNAD 1458
Query: 264 KTMLVEEKLSEIKE--KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ +EEK+ I + + EN + + +M +K DR F + E IL + L++K +
Sbjct: 1459 RKKWLEEKMMLITQAKEAENIRNK-EM--KKYAEDRERFFKQQNEMEILTAQLTEKDSDL 1515
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQL 370
++ EE+ + + L QL +++ + +N ++ +I S+ KI Q+
Sbjct: 1516 QKWREERDQLVAALEIQLKALISSNVQK-DNEIEQLKRIISETSKIETQI 1564
>AL157400-5|CAI16831.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 64.5 bits (150), Expect = 9e-10
Identities = 95/508 (18%), Positives = 214/508 (42%), Gaps = 35/508 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETK 90
KE+ Q++S ++ + + V + KN E I +L ++ + TK
Sbjct: 891 KEVQQIQSNY--DIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTK 948
Query: 91 HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++L+ L DS S++ + N++ S+ + ++ +++ + ++E ++
Sbjct: 949 IDELRTL--DSVSQISNIDLLNLR-DLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQ 1005
Query: 151 IDLKKNSITKDNISIKTLLDKLI---TKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
++NS +I +++ +K I EL I+ L++ Y N +L E+
Sbjct: 1006 EPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK 1065
Query: 208 LNNAVD-----KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ D K+ IQ+ + L+ +N L + A ++E
Sbjct: 1066 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKE 1125
Query: 263 MKTMLVEEKLS-EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
++T+L +K+ K E E + + KL + +EF E +Q+ DL+ K K
Sbjct: 1126 LETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKL 1185
Query: 322 ERELEE---KQEQLTHLMEQLNDTENNSYKLIENMFNKVS-------QIASDFKISNQLS 371
+ E+ + + + HL++ + E + + E + ++S + +D + +
Sbjct: 1186 KEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDY 1245
Query: 372 CELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDN--AQLLWEAKKQIADLT 426
+L ++ + ++I +++ + L +INE +K N +Q L ++ I L
Sbjct: 1246 ADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLK 1305
Query: 427 EQ--NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNE 484
EQ N ++E + Q E K+L ++ + + E++ + L++ E
Sbjct: 1306 EQLNNQKVEEAIQQYERACKDLNVKEKII----EDMRMTLEEQEQTQVEQDQVLEAKLEE 1361
Query: 485 IEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+E + T++ +WK + DL+ Q+ +
Sbjct: 1362 VERLATELEKWKEKCNDLETKNNQRSNK 1389
Score = 53.2 bits (122), Expect = 2e-06
Identities = 85/437 (19%), Positives = 187/437 (42%), Gaps = 41/437 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMH-TSDVMV--VPEIIDSLTEVINTLT 138
E + E +H + L ++ + ++ LK E + + T DV + V E +L+E+ +T
Sbjct: 1058 ENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVT 1117
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDK--LITKNETDINELRNSIKYLESVKS- 195
++E+ ++ +K + + +L+K +I K E ++ E + ++ +SVK+
Sbjct: 1118 CYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQ--DSVKNT 1175
Query: 196 -EYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ N KL E++ N +Q+ LL+++ +
Sbjct: 1176 KDLNVKELKLKEEITQLT---NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQ 1232
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
A+L+ EE +++KEK + K++I + +K + R+ ++ ++ K +++L
Sbjct: 1233 NLKADLQRK-----EEDYADLKEKLTDAKKQIKQV-QKEVSVMRDEDKLLRIK---INEL 1283
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
KK N+ +EL+ KQ + L EQLN+ + +E + + D + ++ ++
Sbjct: 1284 EKKKNQCSQELDMKQRTIQQLKEQLNNQK------VEEAIQQYERACKDLNVKEKIIEDM 1337
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
E E+ + D++ L ++ E ++ W K++ DL +N +
Sbjct: 1338 RMTLEE-QEQTQVEQDQV------LEAKLEEVERLATELEKW--KEKCNDLETKN---NQ 1385
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
R ++ N ++L ++ ++ +E + E E+++ K E
Sbjct: 1386 RSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNK--E 1443
Query: 495 WKSQFEDLDDVMKQQQK 511
K ED + KQQ +
Sbjct: 1444 MKKYAEDRERFFKQQNE 1460
Score = 32.3 bits (70), Expect = 4.2
Identities = 65/350 (18%), Positives = 146/350 (41%), Gaps = 22/350 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTEKLTIA 87
+EI QL + LQ K + +LK +E + ++ L L L
Sbjct: 1187 EEITQLTNNLQDM-----KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1241
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E + DLK+ D+ +++ +++E M D ++ +I + L + N + + +
Sbjct: 1242 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI-NELEKKKNQCSQELDMKQRT 1300
Query: 148 ALEI-DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE 206
++ + N ++ I K + E I ++R +++ E + E + E E
Sbjct: 1301 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 1360
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM--- 263
++ + +E+ + +E +N + +D+ + ++
Sbjct: 1361 EVERLATELEKWKEKCN--DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNAD 1418
Query: 264 KTMLVEEKLSEIKE--KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ +EEK+ I + + EN + + +M +K DR F + E IL + L++K +
Sbjct: 1419 RKKWLEEKMMLITQAKEAENIRNK-EM--KKYAEDRERFFKQQNEMEILTAQLTEKDSDL 1475
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQL 370
++ EE+ + + L QL +++ + +N ++ +I S+ KI Q+
Sbjct: 1476 QKWREERDQLVAALEIQLKALISSNVQK-DNEIEQLKRIISETSKIETQI 1524
>AL157389-3|CAI12887.1| 1780|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1780
Score = 64.5 bits (150), Expect = 9e-10
Identities = 95/508 (18%), Positives = 214/508 (42%), Gaps = 35/508 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETK 90
KE+ Q++S ++ + + V + KN E I +L ++ + TK
Sbjct: 891 KEVQQIQSNY--DIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTK 948
Query: 91 HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++L+ L DS S++ + N++ S+ + ++ +++ + ++E ++
Sbjct: 949 IDELRTL--DSVSQISNIDLLNLR-DLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQ 1005
Query: 151 IDLKKNSITKDNISIKTLLDKLI---TKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
++NS +I +++ +K I EL I+ L++ Y N +L E+
Sbjct: 1006 EPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK 1065
Query: 208 LNNAVD-----KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ D K+ IQ+ + L+ +N L + A ++E
Sbjct: 1066 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKE 1125
Query: 263 MKTMLVEEKLS-EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
++T+L +K+ K E E + + KL + +EF E +Q+ DL+ K K
Sbjct: 1126 LETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKL 1185
Query: 322 ERELEE---KQEQLTHLMEQLNDTENNSYKLIENMFNKVS-------QIASDFKISNQLS 371
+ E+ + + + HL++ + E + + E + ++S + +D + +
Sbjct: 1186 KEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDY 1245
Query: 372 CELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDN--AQLLWEAKKQIADLT 426
+L ++ + ++I +++ + L +INE +K N +Q L ++ I L
Sbjct: 1246 ADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLK 1305
Query: 427 EQ--NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNE 484
EQ N ++E + Q E K+L ++ + + E++ + L++ E
Sbjct: 1306 EQLNNQKVEEAIQQYERACKDLNVKEKII----EDMRMTLEEQEQTQVEQDQVLEAKLEE 1361
Query: 485 IEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+E + T++ +WK + DL+ Q+ +
Sbjct: 1362 VERLATELEKWKEKCNDLETKNNQRSNK 1389
Score = 53.2 bits (122), Expect = 2e-06
Identities = 85/437 (19%), Positives = 187/437 (42%), Gaps = 41/437 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMH-TSDVMV--VPEIIDSLTEVINTLT 138
E + E +H + L ++ + ++ LK E + + T DV + V E +L+E+ +T
Sbjct: 1058 ENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVT 1117
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDK--LITKNETDINELRNSIKYLESVKS- 195
++E+ ++ +K + + +L+K +I K E ++ E + ++ +SVK+
Sbjct: 1118 CYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQ--DSVKNT 1175
Query: 196 -EYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ N KL E++ N +Q+ LL+++ +
Sbjct: 1176 KDLNVKELKLKEEITQLT---NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQ 1232
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
A+L+ EE +++KEK + K++I + +K + R+ ++ ++ K +++L
Sbjct: 1233 NLKADLQRK-----EEDYADLKEKLTDAKKQIKQV-QKEVSVMRDEDKLLRIK---INEL 1283
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
KK N+ +EL+ KQ + L EQLN+ + +E + + D + ++ ++
Sbjct: 1284 EKKKNQCSQELDMKQRTIQQLKEQLNNQK------VEEAIQQYERACKDLNVKEKIIEDM 1337
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
E E+ + D++ L ++ E ++ W K++ DL +N +
Sbjct: 1338 RMTLEE-QEQTQVEQDQV------LEAKLEEVERLATELEKW--KEKCNDLETKN---NQ 1385
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
R ++ N ++L ++ ++ +E + E E+++ K E
Sbjct: 1386 RSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNK--E 1443
Query: 495 WKSQFEDLDDVMKQQQK 511
K ED + KQQ +
Sbjct: 1444 MKKYAEDRERFFKQQNE 1460
Score = 32.3 bits (70), Expect = 4.2
Identities = 65/350 (18%), Positives = 146/350 (41%), Gaps = 22/350 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTEKLTIA 87
+EI QL + LQ K + +LK +E + ++ L L L
Sbjct: 1187 EEITQLTNNLQDM-----KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1241
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E + DLK+ D+ +++ +++E M D ++ +I + L + N + + +
Sbjct: 1242 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI-NELEKKKNQCSQELDMKQRT 1300
Query: 148 ALEI-DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE 206
++ + N ++ I K + E I ++R +++ E + E + E E
Sbjct: 1301 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 1360
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM--- 263
++ + +E+ + +E +N + +D+ + ++
Sbjct: 1361 EVERLATELEKWKEKCN--DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNAD 1418
Query: 264 KTMLVEEKLSEIKE--KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ +EEK+ I + + EN + + +M +K DR F + E IL + L++K +
Sbjct: 1419 RKKWLEEKMMLITQAKEAENIRNK-EM--KKYAEDRERFFKQQNEMEILTAQLTEKDSDL 1475
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQL 370
++ EE+ + + L QL +++ + +N ++ +I S+ KI Q+
Sbjct: 1476 QKWREERDQLVAALEIQLKALISSNVQK-DNEIEQLKRIISETSKIETQI 1524
>AL157389-2|CAI12886.1| 1820|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 1820
Score = 64.5 bits (150), Expect = 9e-10
Identities = 95/508 (18%), Positives = 214/508 (42%), Gaps = 35/508 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETK 90
KE+ Q++S ++ + + V + KN E I +L ++ + TK
Sbjct: 931 KEVQQIQSNY--DIAIAELHVQKSKNQEQEEKIMKLSNEIETATRSITNNVSQIKLMHTK 988
Query: 91 HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++L+ L DS S++ + N++ S+ + ++ +++ + ++E ++
Sbjct: 989 IDELRTL--DSVSQISNIDLLNLR-DLSNGSEEDNLPNTQLDLLGNDYLVSKQVKEYRIQ 1045
Query: 151 IDLKKNSITKDNISIKTLLDKLI---TKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
++NS +I +++ +K I EL I+ L++ Y N +L E+
Sbjct: 1046 EPNRENSFHSSIEAIWEECKEIVKASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEK 1105
Query: 208 LNNAVD-----KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ D K+ IQ+ + L+ +N L + A ++E
Sbjct: 1106 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKE 1165
Query: 263 MKTMLVEEKLS-EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
++T+L +K+ K E E + + KL + +EF E +Q+ DL+ K K
Sbjct: 1166 LETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKL 1225
Query: 322 ERELEE---KQEQLTHLMEQLNDTENNSYKLIENMFNKVS-------QIASDFKISNQLS 371
+ E+ + + + HL++ + E + + E + ++S + +D + +
Sbjct: 1226 KEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDY 1285
Query: 372 CELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDN--AQLLWEAKKQIADLT 426
+L ++ + ++I +++ + L +INE +K N +Q L ++ I L
Sbjct: 1286 ADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLK 1345
Query: 427 EQ--NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNE 484
EQ N ++E + Q E K+L ++ + + E++ + L++ E
Sbjct: 1346 EQLNNQKVEEAIQQYERACKDLNVKEKII----EDMRMTLEEQEQTQVEQDQVLEAKLEE 1401
Query: 485 IEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+E + T++ +WK + DL+ Q+ +
Sbjct: 1402 VERLATELEKWKEKCNDLETKNNQRSNK 1429
Score = 53.2 bits (122), Expect = 2e-06
Identities = 85/437 (19%), Positives = 187/437 (42%), Gaps = 41/437 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMH-TSDVMV--VPEIIDSLTEVINTLT 138
E + E +H + L ++ + ++ LK E + + T DV + V E +L+E+ +T
Sbjct: 1098 ENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVT 1157
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDK--LITKNETDINELRNSIKYLESVKS- 195
++E+ ++ +K + + +L+K +I K E ++ E + ++ +SVK+
Sbjct: 1158 CYKAKIKELETILETQKVECSHSAKLEQDILEKESIILKLERNLKEFQEHLQ--DSVKNT 1215
Query: 196 -EYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ N KL E++ N +Q+ LL+++ +
Sbjct: 1216 KDLNVKELKLKEEITQLT---NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQ 1272
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
A+L+ EE +++KEK + K++I + +K + R+ ++ ++ K +++L
Sbjct: 1273 NLKADLQRK-----EEDYADLKEKLTDAKKQIKQV-QKEVSVMRDEDKLLRIK---INEL 1323
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
KK N+ +EL+ KQ + L EQLN+ + +E + + D + ++ ++
Sbjct: 1324 EKKKNQCSQELDMKQRTIQQLKEQLNNQK------VEEAIQQYERACKDLNVKEKIIEDM 1377
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
E E+ + D++ L ++ E ++ W K++ DL +N +
Sbjct: 1378 RMTLEE-QEQTQVEQDQV------LEAKLEEVERLATELEKW--KEKCNDLETKN---NQ 1425
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
R ++ N ++L ++ ++ +E + E E+++ K E
Sbjct: 1426 RSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNK--E 1483
Query: 495 WKSQFEDLDDVMKQQQK 511
K ED + KQQ +
Sbjct: 1484 MKKYAEDRERFFKQQNE 1500
Score = 32.3 bits (70), Expect = 4.2
Identities = 65/350 (18%), Positives = 146/350 (41%), Gaps = 22/350 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTEKLTIA 87
+EI QL + LQ K + +LK +E + ++ L L L
Sbjct: 1227 EEITQLTNNLQDM-----KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 1281
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E + DLK+ D+ +++ +++E M D ++ +I + L + N + + +
Sbjct: 1282 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI-NELEKKKNQCSQELDMKQRT 1340
Query: 148 ALEI-DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE 206
++ + N ++ I K + E I ++R +++ E + E + E E
Sbjct: 1341 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 1400
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM--- 263
++ + +E+ + +E +N + +D+ + ++
Sbjct: 1401 EVERLATELEKWKEKCN--DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNAD 1458
Query: 264 KTMLVEEKLSEIKE--KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ +EEK+ I + + EN + + +M +K DR F + E IL + L++K +
Sbjct: 1459 RKKWLEEKMMLITQAKEAENIRNK-EM--KKYAEDRERFFKQQNEMEILTAQLTEKDSDL 1515
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQL 370
++ EE+ + + L QL +++ + +N ++ +I S+ KI Q+
Sbjct: 1516 QKWREERDQLVAALEIQLKALISSNVQK-DNEIEQLKRIISETSKIETQI 1564
>AF273042-1|AAG34902.1| 685|Homo sapiens CTCL tumor antigen se1-1
protein.
Length = 685
Score = 63.7 bits (148), Expect = 2e-09
Identities = 86/381 (22%), Positives = 178/381 (46%), Gaps = 40/381 (10%)
Query: 99 EDSASELEALKRENIQMHTSDVMVVPE--IIDSLTEVINTLTNGFESLEEVALEIDLKKN 156
E E+++LK + H ++ + E + DS E + TL + L+E + +K
Sbjct: 165 EQHNREVQSLKEQ----HQKEISELNETFLSDSEKEKL-TLMFEIQGLKEQCENLQQEKQ 219
Query: 157 SITKDNISIKTLLDKLITKNETDINELRNSIKY-LESVKSEYNTANEKLFEQLNNAVDKQ 215
+ S++ +++ L +T++ E I ES+K + + +L ++L A ++
Sbjct: 220 EAILNYESLREIMEIL----QTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEK 275
Query: 216 NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML--VEEKLS 273
+ + E V+ L+ EN+ LL ++ +L + TML +E K++
Sbjct: 276 DALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKIN 335
Query: 274 EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT---ERELEEKQE 330
+ E+ ++F ++ +E++ F++ + + L+ +L KKV +T ELE+K
Sbjct: 336 SLTEEKDDFINKLKNSHEEM----DNFHKKCEREERLILELGKKVEQTIQYNSELEQKVN 391
Query: 331 QLT-HLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYER---IS 386
+LT L E L + + N KL E + ++ ++ D ++ + L +E+ N+ ++ +S
Sbjct: 392 ELTGGLEETLKEKDQNDQKL-EKLMVQMKVLSEDKEVLSAEVKSLYEETINSVQKKKQLS 450
Query: 387 LTLDK---------ITNHITYLNTQIN---ETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
L+ + HIT L ++ E Q N N L E +++ T+ LKE
Sbjct: 451 RDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKE 510
Query: 435 RLSQL--ETENKELLIEIQTV 453
S++ ++E K+++ +Q V
Sbjct: 511 MGSEVSEDSEEKDVVNVLQAV 531
Score = 43.6 bits (98), Expect = 0.002
Identities = 75/357 (21%), Positives = 139/357 (38%), Gaps = 21/357 (5%)
Query: 116 HTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITK 175
H +++ + E+ ++L + + E LE K S + I ++L + T
Sbjct: 11 HEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTF 70
Query: 176 NETDINELRNSIKYLESVKSEYNTANEKLFEQ---LNNAVDKQNCIQEEV-DLLKIENQN 231
E +NE +K+LE E + + L ++ +NN K + + D E ++
Sbjct: 71 VEQVVNE---KVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHERED 127
Query: 232 LLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE 291
L +A L + VE+ E++ E ++EI LNE
Sbjct: 128 LEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELNE 187
Query: 292 KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIE 351
+ D + T+ + L + + + + ++E E L +ME L S I
Sbjct: 188 TFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKIS 247
Query: 352 NMFNKV-SQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKND 410
F + Q ASD EL + + L+ + N + N ++ Q
Sbjct: 248 QEFESMKQQQASDVH-------ELQQKLRTAFTEKDALLETV-NRLQGENEKLLSQQ--- 296
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS 467
+L+ E + I +L E+N + LSQ +T KEL +I ++ ++ LK+S
Sbjct: 297 --ELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKINSLTEEKDDFINKLKNS 351
Score = 39.5 bits (88), Expect = 0.028
Identities = 65/267 (24%), Positives = 116/267 (43%), Gaps = 24/267 (8%)
Query: 88 ETKHNDLKKLYEDSASELEA----LKRENIQMH--TSDVMVVPEIIDSL-TEVINTLTNG 140
E K N+L E++ E + L++ +QM + D V+ + SL E IN++
Sbjct: 387 EQKVNELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEETINSVQKK 446
Query: 141 FESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTA 200
+ ++ + + K++ I K++I T L+K K + + E N K LE+ + +
Sbjct: 447 KQLSRDLEVFLSQKEDVILKEHI---TQLEK---KLQLMVEEQDNLNKLLENEQVQKLFV 500
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX-XXXXARDKFIAN 259
+L+ L + + EE D++ N+LQ RD+ +
Sbjct: 501 KTQLYGFLKEMGSEVSEDSEEKDVV-----NVLQAVGESLAKINEEKCNLAFQRDEKVLE 555
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
LE+ L EE + + +E + D EK++ R+E E EK L SDL + N
Sbjct: 556 LEKEIKCLQEESVVQCEELKSLLR---DYEQEKVLL-RKELEEIQSEKEALQSDLLEMKN 611
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNS 346
E+ E Q L +E+++ T + S
Sbjct: 612 ANEKTRLENQNLLIQ-VEEVSQTCSKS 637
>X75304-1|CAA53052.1| 3259|Homo sapiens giantin protein.
Length = 3259
Score = 62.9 bits (146), Expect = 3e-09
Identities = 87/464 (18%), Positives = 199/464 (42%), Gaps = 44/464 (9%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDS----LTEVIN 135
+T+ AE + +DL++ + +EL N +D + E+++S L + ++
Sbjct: 1908 VTKLKETAEEEKDDLEERLMNQLAELNG-SIGNYCQDVTDAQIKNELLESEMKNLKKCVS 1966
Query: 136 TLTNGFESL--EEVALEIDLKKNSITK--------DNISIKTLLDKLITKNETDINEL-R 184
L + L E+ +E +++K + K N S L +L+ + + ++ +L +
Sbjct: 1967 ELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 2026
Query: 185 NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
+ I+Y E + + T F Q + D + I +E +E++ Q
Sbjct: 2027 DCIRYQEKISALERTVKALEFVQTESQKDLE--ITKENLAQAVEHRKKAQAELASFKVLL 2084
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEK---LSEIKEKDENFKQEIDMLNEKLICDRREFN 301
AR +A+ ++K L K S++K+KDE+ ++ ++ EK + +++
Sbjct: 2085 DDTQSEAAR--VLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQ 2142
Query: 302 ETM----QEKNIL---LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF 354
E + +EK L + ++ +NK ++E+++ QE L + QL + L ++
Sbjct: 2143 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRD 2202
Query: 355 NKVSQIAS-DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQ 413
+ + + K S+ + + ++E + S+ D++ ++ + ++ +
Sbjct: 2203 RVIDEAKKWERKFSDAIQSK-EEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDK 2261
Query: 414 LLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
+WE+K Q +Q + L+ ENKELL ++ EE S
Sbjct: 2262 QIWESKAQTEVQLQQKV-----CDTLQGENKELLSQL-------EETRHLYHSSQNELAK 2309
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+++ D+ + + K Q +L+ +++QQ+ +++ K
Sbjct: 2310 LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK 2353
Score = 56.8 bits (131), Expect = 2e-07
Identities = 68/279 (24%), Positives = 122/279 (43%), Gaps = 30/279 (10%)
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
IK LE++ S+ N L E+ AVDK N + E + +K EN +Q
Sbjct: 2410 IKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEN---IQQKAQLDSFVKSM 2466
Query: 247 XXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQE 306
RD+ + + ++++ E LS I EKD+ QE N KL + R M +
Sbjct: 2467 SSLQNDRDRIVGDYQQLE----ERHLSIILEKDQLI-QEAAAENNKLKEEIRGLRSHMDD 2521
Query: 307 KNILLSDLSKKVNKTERELEE-------KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQ 359
N + L ++ + +L + +Q+QL + Q N N Y +E + +
Sbjct: 2522 LNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEE 2581
Query: 360 IASDFKIS-NQLSCELDDESENTYERISLTLDKITNHITYLNTQ-----------INETQ 407
D + S N L E D S+ E + +++ ++T +T L + + E +
Sbjct: 2582 ANEDLRRSFNALQEEKQDLSKEI-ESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEE 2640
Query: 408 KNDNAQLLWEAKKQIADLTEQNI-ILKERLSQL-ETENK 444
+ + L ++K+IA+L E+ + + KE ++ E E+K
Sbjct: 2641 VHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDK 2679
Score = 49.6 bits (113), Expect = 3e-05
Identities = 101/487 (20%), Positives = 196/487 (40%), Gaps = 48/487 (9%)
Query: 13 ENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTV--AELKNDEINSMIRQLXXXX 70
E I++++ A + +E Y G+L+S + N +K + AE + +E+ +R+
Sbjct: 1630 ERIQHVVEAVRQEKQELY---GKLRS-TEANKKETEKQLQEAEQEMEEMKEKMRKFAKSK 1685
Query: 71 XXXXXXXXXLTEKLTI-----AETKHNDLKKLYEDSASELEALKRENIQMHT--SDVMVV 123
++L +T ++ L +AS E L+R ++ T +
Sbjct: 1686 QQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSL 1745
Query: 124 PEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINEL 183
DSL+E + L + E ++ + + N++ + E D +
Sbjct: 1746 MSEKDSLSEEVQDLKHQIEDNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSM 1805
Query: 184 RNSIKYLESVKS--EYNTANEKLF---EQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXX 238
ESV S N A K F +++NN + + + ++E + L+ E Q +
Sbjct: 1806 STRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1865
Query: 239 XXXXXXXXXXXXXARDKFIANLEEMKTML------VEEKLSEIKEKDENFKQEIDMLNEK 292
+D + L+E T + ++E+LS + + E ++E D L E+
Sbjct: 1866 LENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER 1925
Query: 293 LICDRREFNETM----------QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
L+ E N ++ Q KN LL K + K ELEE+++QL ++
Sbjct: 1926 LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESE 1985
Query: 343 ENNSY-KLIENM----FNK--VSQIASDFKISNQLSCELDDESENTYERISLTLDKITNH 395
Y + I+ NK ++ K Q +L + E+IS L++
Sbjct: 1986 IRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKIS-ALERTVKA 2044
Query: 396 ITYLNTQIN---ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ---LETENKELLIE 449
+ ++ T+ E K + AQ + KK A+L ++L + S+ + +N +L E
Sbjct: 2045 LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKE 2104
Query: 450 IQTVRGS 456
+Q+ + S
Sbjct: 2105 LQSNKES 2111
Score = 48.0 bits (109), Expect = 8e-05
Identities = 99/452 (21%), Positives = 194/452 (42%), Gaps = 80/452 (17%)
Query: 5 EATLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIR 64
E L A+ E + + +H +I ++E ++I L SG ++ + V +AEL+ + I+
Sbjct: 2360 ETDLQASRE-LTSRLHE-EINMKE--QKIISLLSGKEEAIQVA---IAELRQQH-DKEIK 2411
Query: 65 QLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVP 124
+L L E+ A K N L + L+ +K+ENIQ V
Sbjct: 2412 ELENLLSQEEEENIVLEEENKKAVDKTNQLMET-------LKTIKKENIQQKAQLDSFVK 2464
Query: 125 EIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR 184
+ SL + + ++ LEE L I L+K D+LI + + N+L+
Sbjct: 2465 SM-SSLQNDRDRIVGDYQQLEERHLSIILEK--------------DQLIQEAAAENNKLK 2509
Query: 185 NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
I+ L S + N+ N KL +L + + + + + + + + LL+
Sbjct: 2510 EEIRGLRSHMDDLNSENAKLDAEL---IQYREDLNQVITIKDSQQKQLLE---------- 2556
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
++K + N K +EEKL E +E +E+ RR FN
Sbjct: 2557 ----VQLQQNKELEN----KYAKLEEKLKESEEANEDL--------------RRSFNALQ 2594
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+EK DLSK++ + + + Q+T L E+ T + ++ +V ++++ F
Sbjct: 2595 EEK----QDLSKEIESLKVSISQLTRQVTALQEE--GTLGLYHAQLKVKEEEVHRLSALF 2648
Query: 365 KISNQLSCELDDE----SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKK 420
S + EL++E + +++ DK+ + +L+ +N+ A++
Sbjct: 2649 SSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAG-IMRNETE----TAEE 2703
Query: 421 QIADLTEQNIILKERLSQLETENKELLIEIQT 452
++A+L + ++++L + ENK L +IQ+
Sbjct: 2704 RVAELARDLVEMEQKLLMVTKENKGLTAQIQS 2735
Score = 46.0 bits (104), Expect = 3e-04
Identities = 79/459 (17%), Positives = 188/459 (40%), Gaps = 25/459 (5%)
Query: 13 ENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXX 72
E+++ + H ++ E ++ L+S Q G+ + K DE+ +I +
Sbjct: 1354 ESLKTVSHEAEVHAESLQQK---LESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSY 1410
Query: 73 XXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTE 132
LT +T+ + + L + ++LE +E+ + + V + E
Sbjct: 1411 LSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE-RIKQLQVELCEMKQKPE 1469
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES 192
I + + ++ + + K+N K+L ++L T I L S+ +ES
Sbjct: 1470 EIGEESRAKQQIQRKLQAALISRKEALKEN---KSLQEELSLARGT-IERLTKSLADVES 1525
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
S N + + +L ++++ + E+D +ENQ+L
Sbjct: 1526 QVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSL---SSSCESLKLALEGLTED 1582
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL--ICDRRE-----FNETMQ 305
++K + +E +K+ + E +E +EK + ++E ++L + + + E Q
Sbjct: 1583 KEKLVKEIESLKSSKIAES-TEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQ 1641
Query: 306 EKNILLSDL-SKKVNK--TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
EK L L S + NK TE++L+E ++++ + E++ + + I + + ++ +
Sbjct: 1642 EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDRLRA 1701
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINE--TQKNDNAQLLWEAKK 420
+ + + E + ++ + L+++ L+ + ++K+ ++ + + K
Sbjct: 1702 EVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSLMSEKDSLSEEVQDLKH 1761
Query: 421 QIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
QI D + L E + + + Q++ G EE
Sbjct: 1762 QIEDNVSKQANL-EATEKHDNQTNVTEEGTQSIPGETEE 1799
Score = 41.9 bits (94), Expect = 0.005
Identities = 74/361 (20%), Positives = 140/361 (38%), Gaps = 36/361 (9%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDN---ISIKTLLDKLITKNETDIN-EL 183
+ L E I L + + L ++D + +D I+IK K + + + N EL
Sbjct: 2506 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKEL 2565
Query: 184 RNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXX 243
N LE E ANE L N +++ + +E++ LK+ L +
Sbjct: 2566 ENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEG 2625
Query: 244 X----------------XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEID 287
+ K IA LEE + +E ++ E ++ K+E+
Sbjct: 2626 TLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELK 2685
Query: 288 MLNEKLICDRREFNETMQEKNILLS----DLSKK---VNKTERELEEKQEQLTHLMEQLN 340
L+ R E ET +E+ L+ ++ +K V K + L + + M L
Sbjct: 2686 HLHHDAGIMRNE-TETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQ 2744
Query: 341 DTENNSYKLIENMFNKVS---QIASDFKISNQLSCELDDESENTYERISLTLDKITNHIT 397
++ +++ + ++ + K + + K L+ E D T ++ T + +H+
Sbjct: 2745 NSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLE 2804
Query: 398 YLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSN 457
LN Q+ + + QLL Q+ D Q + ++ L+ E L E++ R S
Sbjct: 2805 KLNQQL----LSKDEQLL-HLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSE 2859
Query: 458 E 458
E
Sbjct: 2860 E 2860
Score = 41.1 bits (92), Expect = 0.009
Identities = 78/442 (17%), Positives = 172/442 (38%), Gaps = 28/442 (6%)
Query: 10 ANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXX 69
A N ++ I + +++ E +L + L Q ++ + +K+ + ++
Sbjct: 2503 AENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVIT-IKDSQQKQLLEVQLQQ 2561
Query: 70 XXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDS 129
L EKL +E + DL++ + E + L +E + S I
Sbjct: 2562 NKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVS--------ISQ 2613
Query: 130 LTEVINTLTN-GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIK 188
LT + L G L L++ K+ + + + + ++ E + + + K
Sbjct: 2614 LTRQVTALQEEGTLGLYHAQLKV--KEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAK 2671
Query: 189 YLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXX 248
+ ++ + + L ++ +E V L + + Q
Sbjct: 2672 KVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTA 2731
Query: 249 XXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRRE---FNETMQ 305
+ + +++L+ + EE L E+K K + +E+ L E+ + +R +ET
Sbjct: 2732 QIQSFGRSMSSLQNSRDHANEE-LDELKRKYDASLKELAQLKEQGLLNRERDALLSETAF 2790
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-F 364
N + + K ++L K EQL HL QL D SY +++ ++ + ++
Sbjct: 2791 SMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLED----SYNQVQSFSKAMASLQNERD 2846
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD 424
+ N+L E +SE +R + + L ++ Q ND +LL K++ +
Sbjct: 2847 HLWNEL--EKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQ-NDRDRLL----KELKN 2899
Query: 425 LTEQNIILKERLSQLETENKEL 446
L +Q + + + +++L +L
Sbjct: 2900 LQQQYLQINQEITELHPLKAQL 2921
Score = 40.3 bits (90), Expect = 0.016
Identities = 68/421 (16%), Positives = 177/421 (42%), Gaps = 12/421 (2%)
Query: 96 KLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKK 155
K E + +E E +R + + T+ ++ E I SL+ + E L+ E+D +
Sbjct: 767 KQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQN---ELDDVQ 823
Query: 156 NSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQ 215
++ + I++L +L K E+++ E ++++ S E + A + ++L Q
Sbjct: 824 LQFSEQSTLIRSLQSQLQNK-ESEVLEGAERVRHISSKVEELSQALSQ--KELEITKMDQ 880
Query: 216 NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEI 275
++++ D+ ++ + ++ + E+KT+ +E+L+ +
Sbjct: 881 LLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTL--KEQLNLL 938
Query: 276 KEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL 335
+E K++++ NE ++ ++E I +L + + ++E E+++ +L
Sbjct: 939 SRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAA 998
Query: 336 MEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNH 395
+ + +L E + N + + +S E++++ EN K
Sbjct: 999 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEI 1058
Query: 396 ITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRG 455
YL I+E ++ + + + ++++A + ++K+ L+ + ++ + +Q
Sbjct: 1059 EIYLKQTISE-KEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDL-LQAEIS 1116
Query: 456 SNEEVTLNLKDSSTXXXXXXXXXXXXSN-EIEDMKTKVME-WKSQFEDLDDVMKQQQKEL 513
N+ + L S+T I T E WK + E+ +++++++L
Sbjct: 1117 ENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQL 1176
Query: 514 K 514
+
Sbjct: 1177 Q 1177
Score = 38.7 bits (86), Expect = 0.049
Identities = 81/416 (19%), Positives = 171/416 (41%), Gaps = 38/416 (9%)
Query: 104 ELEALKRE---NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITK 160
E+EA K E + TS++ E + L E IN ESL+ V+ E ++ S+ +
Sbjct: 1313 EIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQ 1372
Query: 161 DNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQE 220
K +L + EL+ + L+ + S+ L QL+ IQ
Sbjct: 1373 -----KLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQT 1427
Query: 221 EVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDE 280
E+ IE ++L++ D+ I L+ ++ +++K EI E +
Sbjct: 1428 EI----IEQEDLIKALHTQLEMQAKE------HDERIKQLQ-VELCEMKQKPEEIGE-ES 1475
Query: 281 NFKQEIDMLNEKLICDRREF---NETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLME 337
KQ+I + + R+E N+++QE+ L +++ K+ ++E +
Sbjct: 1476 RAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQ----VSAQN 1531
Query: 338 QLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHIT 397
+ DT L++ +K+ + NQ ++ E + L L+ +T
Sbjct: 1532 KEKDTVLGRLALLQEERDKLITEMDRSLLENQ-------SLSSSCESLKLALEGLTEDKE 1584
Query: 398 YLNTQINETQKNDNAQLL-WEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
L +I + + A+ W+ K + +L ++ IL + + E + + ++ VR
Sbjct: 1585 KLVKEIESLKSSKIAESTEWQEKHK--ELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1642
Query: 457 NEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW-KSQFEDLDDVMKQQQK 511
+E+ L+ + E+E+MK K+ ++ KS+ + + ++ ++ +
Sbjct: 1643 KQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDR 1698
Score = 38.7 bits (86), Expect = 0.049
Identities = 75/384 (19%), Positives = 170/384 (44%), Gaps = 35/384 (9%)
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+L++L ++ E++ L+++ I+ + + + + +L V E + E +A +
Sbjct: 2009 ELQELLKEKQQEVKQLQKDCIR-YQEKISALERTVKALEFVQTESQKDLEITKENLAQAV 2067
Query: 152 DLKKNSITKDNISIKTLLDKLITKNE---TDINELRNSIKY-LESVKSEYNTANEKLFEQ 207
+ +K + + S K LLD ++ D +L+ ++ ESVKS+ +E L +
Sbjct: 2068 EHRKKA-QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERR 2126
Query: 208 LNNAVDK----QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L A +K + +QE++D L+ E +L + +DK + L+E
Sbjct: 2127 LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK-------KDKEVQQLQEN 2179
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
V + L+ + + + + D + ++ R+F++ +Q K +++ E
Sbjct: 2180 LDSTVTQ-LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKE-------EEIRLKED 2231
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
++QL + + + + N +L + S+ ++ ++ ++ L E++
Sbjct: 2232 NCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLS 2291
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETEN 443
++ + T H+ Y ++Q NE K ++ L K Q+ DL+ KE+ LE
Sbjct: 2292 QL-----EETRHL-YHSSQ-NELAKLESE--LKSLKDQLTDLSNSLEKCKEQKGNLEGII 2342
Query: 444 KELLIEIQTVRGSNEEVTLNLKDS 467
++ +IQ + S E++ +L+ S
Sbjct: 2343 RQQEADIQNSKFSYEQLETDLQAS 2366
Score = 37.9 bits (84), Expect = 0.085
Identities = 62/288 (21%), Positives = 127/288 (44%), Gaps = 42/288 (14%)
Query: 267 LVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
L++++L+ +++++ Q++ + + R +E ILL + +V + +
Sbjct: 277 LLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFH 336
Query: 327 EKQEQLTHLMEQLNDTE------NNSYKLIE-----NMFNKVSQIASDFKISNQL--SCE 373
QE++ HL+EQ + Y +E M K S I S K +L +C+
Sbjct: 337 NLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACD 396
Query: 374 ---------LDDESE------NTYERISLTLDKITNHIT-YLN---TQINETQKNDNAQL 414
L D++E T +++ L + + I+ +LN Q +ET +
Sbjct: 397 ALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPD 456
Query: 415 LWEAKKQIADLTEQNII-LKERLSQLETENKELL---IEIQTVRGSNEEVT--LNLKDSS 468
++ Q +TE+NI L++R+ +LE E LL IE++ ++ NE+++ + L ++
Sbjct: 457 VYNEGTQA--VTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQ 514
Query: 469 TXXXXXXXXXXXXS-NEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
S +I + ++ E Q + L++ Q+ KEL +
Sbjct: 515 NRTGEADREVSEISIVDIANKRSSSAEESGQ-DVLENTFSQKHKELSV 561
Score = 33.9 bits (74), Expect = 1.4
Identities = 53/259 (20%), Positives = 108/259 (41%), Gaps = 26/259 (10%)
Query: 269 EEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE---- 324
EE+LS+ + + EI+ + KL ++ E T+Q + + TE E
Sbjct: 129 EEQLSKHDKSSTEEEMEIEKIKHKLQ-EKEELISTLQAQLTQAQAEQPAQSSTEMEEFVM 187
Query: 325 ----LEEKQEQLTHLMEQLNDT--ENNSYKLI-ENMFNKVSQIASDFKISNQLSCELDDE 377
L+EK+E ++ L QL+ T E + +++ E +Q+ QL + D E
Sbjct: 188 MKQQLQEKEEFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVE 247
Query: 378 SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS 437
+E +++ + K+ H E AQ++ ++++ ++N IL ++L
Sbjct: 248 TE-MQQKLRVLQRKLEEH---------EESLVGRAQVVDLLQQELTAAEQRNQILSQQLQ 297
Query: 438 QLETENKELLIEIQTVRGSN----EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
Q+E E+ L ++T R + E++ L + + + E
Sbjct: 298 QMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQA 357
Query: 494 EWKSQFEDLDDVMKQQQKE 512
E +S++ L+ K + +E
Sbjct: 358 ELESRYSALEQKHKAEMEE 376
Score = 33.9 bits (74), Expect = 1.4
Identities = 53/248 (21%), Positives = 97/248 (39%), Gaps = 13/248 (5%)
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEE 327
+E L +E +EI+M +K+I E +Q + +++L ++ +K +ELE
Sbjct: 2359 LETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQ---VAIAELRQQHDKEIKELEN 2415
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN-QLSCELDDESENTYERIS 386
Q E+ N K + N++ + K N Q +L D + +
Sbjct: 2416 LLSQ----EEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL-DSFVKSMSSLQ 2470
Query: 387 LTLDKITNHITYLNTQ-INETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
D+I L + ++ + D QL+ EA + L E+ L+ + L +EN +
Sbjct: 2471 NDRDRIVGDYQQLEERHLSIILEKD--QLIQEAAAENNKLKEEIRGLRSHMDDLNSENAK 2528
Query: 446 LLIE-IQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDD 504
L E IQ N+ +T+ N+ ++ K+ E + EDL
Sbjct: 2529 LDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRR 2588
Query: 505 VMKQQQKE 512
Q+E
Sbjct: 2589 SFNALQEE 2596
>D25542-1|BAA05025.1| 3225|Homo sapiens golgi antigen gcp372 protein.
Length = 3225
Score = 62.9 bits (146), Expect = 3e-09
Identities = 87/464 (18%), Positives = 199/464 (42%), Gaps = 44/464 (9%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDS----LTEVIN 135
+T+ AE + +DL++ + +EL N +D + E+++S L + ++
Sbjct: 1874 VTKLKETAEEEKDDLEERLMNQLAELNG-SIGNYCQDVTDAQIKNELLESEMKNLKKCVS 1932
Query: 136 TLTNGFESL--EEVALEIDLKKNSITK--------DNISIKTLLDKLITKNETDINEL-R 184
L + L E+ +E +++K + K N S L +L+ + + ++ +L +
Sbjct: 1933 ELEEEKQQLVKEKTKVESEIRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQK 1992
Query: 185 NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
+ I+Y E + + T F Q + D + I +E +E++ Q
Sbjct: 1993 DCIRYQEKISALERTVKALEFVQTESQKDLE--ITKENLAQAVEHRKKAQAELASFKVLL 2050
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEK---LSEIKEKDENFKQEIDMLNEKLICDRREFN 301
AR +A+ ++K L K S++K+KDE+ ++ ++ EK + +++
Sbjct: 2051 DDTQSEAAR--VLADNLKLKKELQSNKESVKSQMKQKDEDLERRLEQAEEKHLKEKKNMQ 2108
Query: 302 ETM----QEKNIL---LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF 354
E + +EK L + ++ +NK ++E+++ QE L + QL + L ++
Sbjct: 2109 EKLDALRREKVHLEETIGEIQVTLNKKDKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRD 2168
Query: 355 NKVSQIAS-DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQ 413
+ + + K S+ + + ++E + S+ D++ ++ + ++ +
Sbjct: 2169 RVIDEAKKWERKFSDAIQSK-EEEIRLKEDNCSVLKDQLRQMSIHMEELKINISRLEHDK 2227
Query: 414 LLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
+WE+K Q +Q + L+ ENKELL ++ EE S
Sbjct: 2228 QIWESKAQTEVQLQQKV-----CDTLQGENKELLSQL-------EETRHLYHSSQNELAK 2275
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+++ D+ + + K Q +L+ +++QQ+ +++ K
Sbjct: 2276 LESELKSLKDQLTDLSNSLEKCKEQKGNLEGIIRQQEADIQNSK 2319
Score = 56.8 bits (131), Expect = 2e-07
Identities = 68/279 (24%), Positives = 122/279 (43%), Gaps = 30/279 (10%)
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
IK LE++ S+ N L E+ AVDK N + E + +K EN +Q
Sbjct: 2376 IKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLKTIKKEN---IQQKAQLDSFVKSM 2432
Query: 247 XXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQE 306
RD+ + + ++++ E LS I EKD+ QE N KL + R M +
Sbjct: 2433 SSLQNDRDRIVGDYQQLE----ERHLSIILEKDQLI-QEAAAENNKLKEEIRGLRSHMDD 2487
Query: 307 KNILLSDLSKKVNKTERELEE-------KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQ 359
N + L ++ + +L + +Q+QL + Q N N Y +E + +
Sbjct: 2488 LNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEE 2547
Query: 360 IASDFKIS-NQLSCELDDESENTYERISLTLDKITNHITYLNTQ-----------INETQ 407
D + S N L E D S+ E + +++ ++T +T L + + E +
Sbjct: 2548 ANEDLRRSFNALQEEKQDLSKEI-ESLKVSISQLTRQVTALQEEGTLGLYHAQLKVKEEE 2606
Query: 408 KNDNAQLLWEAKKQIADLTEQNI-ILKERLSQL-ETENK 444
+ + L ++K+IA+L E+ + + KE ++ E E+K
Sbjct: 2607 VHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDK 2645
Score = 49.6 bits (113), Expect = 3e-05
Identities = 101/487 (20%), Positives = 196/487 (40%), Gaps = 48/487 (9%)
Query: 13 ENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTV--AELKNDEINSMIRQLXXXX 70
E I++++ A + +E Y G+L+S + N +K + AE + +E+ +R+
Sbjct: 1596 ERIQHVVEAVRQEKQELY---GKLRS-TEANKKETEKQLQEAEQEMEEMKEKMRKFAKSK 1651
Query: 71 XXXXXXXXXLTEKLTI-----AETKHNDLKKLYEDSASELEALKRENIQMHT--SDVMVV 123
++L +T ++ L +AS E L+R ++ T +
Sbjct: 1652 QQKILELEEENDRLRAEVHPAGDTAKECMETLLSSNASMKEELERVKMEYETLSKKFQSL 1711
Query: 124 PEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINEL 183
DSL+E + L + E ++ + + N++ + E D +
Sbjct: 1712 MSEKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSM 1771
Query: 184 RNSIKYLESVKS--EYNTANEKLF---EQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXX 238
ESV S N A K F +++NN + + + ++E + L+ E Q +
Sbjct: 1772 STRPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQT 1831
Query: 239 XXXXXXXXXXXXXARDKFIANLEEMKTML------VEEKLSEIKEKDENFKQEIDMLNEK 292
+D + L+E T + ++E+LS + + E ++E D L E+
Sbjct: 1832 LENEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEER 1891
Query: 293 LICDRREFNETM----------QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
L+ E N ++ Q KN LL K + K ELEE+++QL ++
Sbjct: 1892 LMNQLAELNGSIGNYCQDVTDAQIKNELLESEMKNLKKCVSELEEEKQQLVKEKTKVESE 1951
Query: 343 ENNSY-KLIENM----FNK--VSQIASDFKISNQLSCELDDESENTYERISLTLDKITNH 395
Y + I+ NK ++ K Q +L + E+IS L++
Sbjct: 1952 IRKEYLEKIQGAQKEPGNKSHAKELQELLKEKQQEVKQLQKDCIRYQEKIS-ALERTVKA 2010
Query: 396 ITYLNTQIN---ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ---LETENKELLIE 449
+ ++ T+ E K + AQ + KK A+L ++L + S+ + +N +L E
Sbjct: 2011 LEFVQTESQKDLEITKENLAQAVEHRKKAQAELASFKVLLDDTQSEAARVLADNLKLKKE 2070
Query: 450 IQTVRGS 456
+Q+ + S
Sbjct: 2071 LQSNKES 2077
Score = 48.0 bits (109), Expect = 8e-05
Identities = 99/452 (21%), Positives = 194/452 (42%), Gaps = 80/452 (17%)
Query: 5 EATLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIR 64
E L A+ E + + +H +I ++E ++I L SG ++ + V +AEL+ + I+
Sbjct: 2326 ETDLQASRE-LTSRLHE-EINMKE--QKIISLLSGKEEAIQVA---IAELRQQH-DKEIK 2377
Query: 65 QLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVP 124
+L L E+ A K N L + L+ +K+ENIQ V
Sbjct: 2378 ELENLLSQEEEENIVLEEENKKAVDKTNQLMET-------LKTIKKENIQQKAQLDSFVK 2430
Query: 125 EIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR 184
+ SL + + ++ LEE L I L+K D+LI + + N+L+
Sbjct: 2431 SM-SSLQNDRDRIVGDYQQLEERHLSIILEK--------------DQLIQEAAAENNKLK 2475
Query: 185 NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
I+ L S + N+ N KL +L + + + + + + + + LL+
Sbjct: 2476 EEIRGLRSHMDDLNSENAKLDAEL---IQYREDLNQVITIKDSQQKQLLE---------- 2522
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
++K + N K +EEKL E +E +E+ RR FN
Sbjct: 2523 ----VQLQQNKELEN----KYAKLEEKLKESEEANEDL--------------RRSFNALQ 2560
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+EK DLSK++ + + + Q+T L E+ T + ++ +V ++++ F
Sbjct: 2561 EEK----QDLSKEIESLKVSISQLTRQVTALQEE--GTLGLYHAQLKVKEEEVHRLSALF 2614
Query: 365 KISNQLSCELDDE----SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKK 420
S + EL++E + +++ DK+ + +L+ +N+ A++
Sbjct: 2615 SSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELKHLHHDAG-IMRNETE----TAEE 2669
Query: 421 QIADLTEQNIILKERLSQLETENKELLIEIQT 452
++A+L + ++++L + ENK L +IQ+
Sbjct: 2670 RVAELARDLVEMEQKLLMVTKENKGLTAQIQS 2701
Score = 45.2 bits (102), Expect = 6e-04
Identities = 60/354 (16%), Positives = 143/354 (40%), Gaps = 15/354 (4%)
Query: 13 ENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXX 72
E+++ + H ++ E ++ L+S Q G+ + K DE+ +I +
Sbjct: 1320 ESLKTVSHEAEVHAESLQQK---LESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSY 1376
Query: 73 XXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTE 132
LT +T+ + + L + ++LE +E+ + + V + E
Sbjct: 1377 LSGQLSEKEAALTKIQTEIIEQEDLIKALHTQLEMQAKEHDE-RIKQLQVELCEMKQKPE 1435
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES 192
I + + ++ + + K+N K+L ++L T I L S+ +ES
Sbjct: 1436 EIGEESRAKQQIQRKLQAALISRKEALKEN---KSLQEELSLARGT-IERLTKSLADVES 1491
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
S N + + +L ++++ + E+D +ENQ+L
Sbjct: 1492 QVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSL---SSSCESLKLALEGLTED 1548
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDML---NEKLICDRREFNETMQEKNI 309
++K + +E +K+ + E +E +EK + ++E ++L E + + ++
Sbjct: 1549 KEKLVKEIESLKSSKIAES-TEWQEKHKELQKEYEILLQSYENVSNEAERIQHVVEAVRQ 1607
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+L K+ TE +E ++QL +++ + + K ++ K+ ++ +
Sbjct: 1608 EKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEE 1661
Score = 41.9 bits (94), Expect = 0.005
Identities = 74/361 (20%), Positives = 140/361 (38%), Gaps = 36/361 (9%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDN---ISIKTLLDKLITKNETDIN-EL 183
+ L E I L + + L ++D + +D I+IK K + + + N EL
Sbjct: 2472 NKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKEL 2531
Query: 184 RNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXX 243
N LE E ANE L N +++ + +E++ LK+ L +
Sbjct: 2532 ENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVSISQLTRQVTALQEEG 2591
Query: 244 X----------------XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEID 287
+ K IA LEE + +E ++ E ++ K+E+
Sbjct: 2592 TLGLYHAQLKVKEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAKKVGEIEDKLKKELK 2651
Query: 288 MLNEKLICDRREFNETMQEKNILLS----DLSKK---VNKTERELEEKQEQLTHLMEQLN 340
L+ R E ET +E+ L+ ++ +K V K + L + + M L
Sbjct: 2652 HLHHDAGIMRNE-TETAEERVAELARDLVEMEQKLLMVTKENKGLTAQIQSFGRSMSSLQ 2710
Query: 341 DTENNSYKLIENMFNKVS---QIASDFKISNQLSCELDDESENTYERISLTLDKITNHIT 397
++ +++ + ++ + K + + K L+ E D T ++ T + +H+
Sbjct: 2711 NSRDHANEELDELKRKYDASLKELAQLKEQGLLNRERDALLSETAFSMNSTEENSLSHLE 2770
Query: 398 YLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSN 457
LN Q+ + + QLL Q+ D Q + ++ L+ E L E++ R S
Sbjct: 2771 KLNQQL----LSKDEQLL-HLSSQLEDSYNQVQSFSKAMASLQNERDHLWNELEKFRKSE 2825
Query: 458 E 458
E
Sbjct: 2826 E 2826
Score = 41.1 bits (92), Expect = 0.009
Identities = 78/442 (17%), Positives = 172/442 (38%), Gaps = 28/442 (6%)
Query: 10 ANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXX 69
A N ++ I + +++ E +L + L Q ++ + +K+ + ++
Sbjct: 2469 AENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVIT-IKDSQQKQLLEVQLQQ 2527
Query: 70 XXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDS 129
L EKL +E + DL++ + E + L +E + S I
Sbjct: 2528 NKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEIESLKVS--------ISQ 2579
Query: 130 LTEVINTLTN-GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIK 188
LT + L G L L++ K+ + + + + ++ E + + + K
Sbjct: 2580 LTRQVTALQEEGTLGLYHAQLKV--KEEEVHRLSALFSSSQKRIAELEEELVCVQKEAAK 2637
Query: 189 YLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXX 248
+ ++ + + L ++ +E V L + + Q
Sbjct: 2638 KVGEIEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVEMEQKLLMVTKENKGLTA 2697
Query: 249 XXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRRE---FNETMQ 305
+ + +++L+ + EE L E+K K + +E+ L E+ + +R +ET
Sbjct: 2698 QIQSFGRSMSSLQNSRDHANEE-LDELKRKYDASLKELAQLKEQGLLNRERDALLSETAF 2756
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-F 364
N + + K ++L K EQL HL QL D SY +++ ++ + ++
Sbjct: 2757 SMNSTEENSLSHLEKLNQQLLSKDEQLLHLSSQLED----SYNQVQSFSKAMASLQNERD 2812
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD 424
+ N+L E +SE +R + + L ++ Q ND +LL K++ +
Sbjct: 2813 HLWNEL--EKFRKSEEGKQRSAAQPSTSPAEVQSLKKAMSSLQ-NDRDRLL----KELKN 2865
Query: 425 LTEQNIILKERLSQLETENKEL 446
L +Q + + + +++L +L
Sbjct: 2866 LQQQYLQINQEITELHPLKAQL 2887
Score = 40.3 bits (90), Expect = 0.016
Identities = 50/258 (19%), Positives = 110/258 (42%), Gaps = 19/258 (7%)
Query: 269 EEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE---- 324
EE+LS+ + + EI+ + KL ++ E T+Q + + TE E
Sbjct: 90 EEQLSKHDKSSTEEEMEIEKIKHKLQ-EKEELISTLQAQLTQAQAEQPAQSSTEMEEFVM 148
Query: 325 ----LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
L+EK+E ++ L QL+ T+ + +M V + + F+ +L +DE
Sbjct: 149 MKQQLQEKEEFISTLQAQLSQTQAEQAAQLSSMQQVVREKDARFETQVRLH---EDELLQ 205
Query: 381 TYERISLTLDKITNHITYLNTQINETQKN--DNAQLLWEAKKQIADLTEQNIILKERLSQ 438
+ + + + + L ++ E +++ AQ++ ++++ ++N IL ++L Q
Sbjct: 206 LVTQADVETE-MQQKLRVLQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQ 264
Query: 439 LETENKELLIEIQTVRGSN----EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
+E E+ L ++T R + E++ L + + + E E
Sbjct: 265 MEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFHNLQEEMHHLLEQFEQAGQAQAE 324
Query: 495 WKSQFEDLDDVMKQQQKE 512
+S++ L+ K + +E
Sbjct: 325 LESRYSALEQKHKAEMEE 342
Score = 40.3 bits (90), Expect = 0.016
Identities = 68/421 (16%), Positives = 177/421 (42%), Gaps = 12/421 (2%)
Query: 96 KLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKK 155
K E + +E E +R + + T+ ++ E I SL+ + E L+ E+D +
Sbjct: 733 KQLEMNLAEAERQRRLDYESQTAHDNLLTEQIHSLSIEAKSKDVKIEVLQN---ELDDVQ 789
Query: 156 NSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQ 215
++ + I++L +L K E+++ E ++++ S E + A + ++L Q
Sbjct: 790 LQFSEQSTLIRSLQSQLQNK-ESEVLEGAERVRHISSKVEELSQALSQ--KELEITKMDQ 846
Query: 216 NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEI 275
++++ D+ ++ + ++ + E+KT+ +E+L+ +
Sbjct: 847 LLLEKKRDVETLQQTIEEKDQQVTEISFSMTEKMVQLNEEKFSLGVEIKTL--KEQLNLL 904
Query: 276 KEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL 335
+E K++++ NE ++ ++E I +L + + ++E E+++ +L
Sbjct: 905 SRAEEAKKEQVEEDNEVSSGLKQNYDEMSPAGQISKEELQHEFDLLKKENEQRKRKLQAA 964
Query: 336 MEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNH 395
+ + +L E + N + + +S E++++ EN K
Sbjct: 965 LINRKELLQRVSRLEEELANLKDESKKEIPLSETERGEVEEDKENKEYSEKCVTSKCQEI 1024
Query: 396 ITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRG 455
YL I+E ++ + + + ++++A + ++K+ L+ + ++ + +Q
Sbjct: 1025 EIYLKQTISE-KEVELQHIRKDLEEKLAAEEQFQALVKQMNQTLQDKTNQIDL-LQAEIS 1082
Query: 456 SNEEVTLNLKDSSTXXXXXXXXXXXXSN-EIEDMKTKVME-WKSQFEDLDDVMKQQQKEL 513
N+ + L S+T I T E WK + E+ +++++++L
Sbjct: 1083 ENQAIIQKLITSNTDASDGDSVALVKETVVISPPCTGSSEHWKPELEEKILALEKEKEQL 1142
Query: 514 K 514
+
Sbjct: 1143 Q 1143
Score = 38.7 bits (86), Expect = 0.049
Identities = 81/416 (19%), Positives = 171/416 (41%), Gaps = 38/416 (9%)
Query: 104 ELEALKRE---NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITK 160
E+EA K E + TS++ E + L E IN ESL+ V+ E ++ S+ +
Sbjct: 1279 EIEAEKVELELKVSSTTSELTKKSEEVFQLQEQINKQGLEIESLKTVSHEAEVHAESLQQ 1338
Query: 161 DNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQE 220
K +L + EL+ + L+ + S+ L QL+ IQ
Sbjct: 1339 -----KLESSQLQIAGLEHLRELQPKLDELQKLISKKEEDVSYLSGQLSEKEAALTKIQT 1393
Query: 221 EVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDE 280
E+ IE ++L++ D+ I L+ ++ +++K EI E +
Sbjct: 1394 EI----IEQEDLIKALHTQLEMQAKE------HDERIKQLQ-VELCEMKQKPEEIGE-ES 1441
Query: 281 NFKQEIDMLNEKLICDRREF---NETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLME 337
KQ+I + + R+E N+++QE+ L +++ K+ ++E +
Sbjct: 1442 RAKQQIQRKLQAALISRKEALKENKSLQEELSLARGTIERLTKSLADVESQ----VSAQN 1497
Query: 338 QLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHIT 397
+ DT L++ +K+ + NQ ++ E + L L+ +T
Sbjct: 1498 KEKDTVLGRLALLQEERDKLITEMDRSLLENQ-------SLSSSCESLKLALEGLTEDKE 1550
Query: 398 YLNTQINETQKNDNAQLL-WEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
L +I + + A+ W+ K + +L ++ IL + + E + + ++ VR
Sbjct: 1551 KLVKEIESLKSSKIAESTEWQEKHK--ELQKEYEILLQSYENVSNEAERIQHVVEAVRQE 1608
Query: 457 NEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW-KSQFEDLDDVMKQQQK 511
+E+ L+ + E+E+MK K+ ++ KS+ + + ++ ++ +
Sbjct: 1609 KQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKILELEEENDR 1664
Score = 38.7 bits (86), Expect = 0.049
Identities = 75/384 (19%), Positives = 170/384 (44%), Gaps = 35/384 (9%)
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+L++L ++ E++ L+++ I+ + + + + +L V E + E +A +
Sbjct: 1975 ELQELLKEKQQEVKQLQKDCIR-YQEKISALERTVKALEFVQTESQKDLEITKENLAQAV 2033
Query: 152 DLKKNSITKDNISIKTLLDKLITKNE---TDINELRNSIKY-LESVKSEYNTANEKLFEQ 207
+ +K + + S K LLD ++ D +L+ ++ ESVKS+ +E L +
Sbjct: 2034 EHRKKA-QAELASFKVLLDDTQSEAARVLADNLKLKKELQSNKESVKSQMKQKDEDLERR 2092
Query: 208 LNNAVDK----QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L A +K + +QE++D L+ E +L + +DK + L+E
Sbjct: 2093 LEQAEEKHLKEKKNMQEKLDALRREKVHLEETIGEIQVTLNK-------KDKEVQQLQEN 2145
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
V + L+ + + + + D + ++ R+F++ +Q K +++ E
Sbjct: 2146 LDSTVTQ-LAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKE-------EEIRLKED 2197
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
++QL + + + + N +L + S+ ++ ++ ++ L E++
Sbjct: 2198 NCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCDTLQGENKELLS 2257
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETEN 443
++ + T H+ Y ++Q NE K ++ L K Q+ DL+ KE+ LE
Sbjct: 2258 QL-----EETRHL-YHSSQ-NELAKLESE--LKSLKDQLTDLSNSLEKCKEQKGNLEGII 2308
Query: 444 KELLIEIQTVRGSNEEVTLNLKDS 467
++ +IQ + S E++ +L+ S
Sbjct: 2309 RQQEADIQNSKFSYEQLETDLQAS 2332
Score = 37.9 bits (84), Expect = 0.085
Identities = 62/288 (21%), Positives = 127/288 (44%), Gaps = 42/288 (14%)
Query: 267 LVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
L++++L+ +++++ Q++ + + R +E ILL + +V + +
Sbjct: 243 LLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREESKILLEKMELEVAERKLSFH 302
Query: 327 EKQEQLTHLMEQLNDTE------NNSYKLIE-----NMFNKVSQIASDFKISNQL--SCE 373
QE++ HL+EQ + Y +E M K S I S K +L +C+
Sbjct: 303 NLQEEMHHLLEQFEQAGQAQAELESRYSALEQKHKAEMEEKTSHILSLQKTGQELQSACD 362
Query: 374 ---------LDDESE------NTYERISLTLDKITNHIT-YLN---TQINETQKNDNAQL 414
L D++E T +++ L + + I+ +LN Q +ET +
Sbjct: 363 ALKDQNSKLLQDKNEQAVQSAQTIQQLEDQLQQKSKEISQFLNRLPLQQHETASQTSFPD 422
Query: 415 LWEAKKQIADLTEQNII-LKERLSQLETENKELL---IEIQTVRGSNEEVT--LNLKDSS 468
++ Q +TE+NI L++R+ +LE E LL IE++ ++ NE+++ + L ++
Sbjct: 423 VYNEGTQA--VTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQITLLEAQ 480
Query: 469 TXXXXXXXXXXXXS-NEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
S +I + ++ E Q + L++ Q+ KEL +
Sbjct: 481 NRTGEADREVSEISIVDIANKRSSSAEESGQ-DVLENTFSQKHKELSV 527
Score = 33.9 bits (74), Expect = 1.4
Identities = 53/248 (21%), Positives = 97/248 (39%), Gaps = 13/248 (5%)
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEE 327
+E L +E +EI+M +K+I E +Q + +++L ++ +K +ELE
Sbjct: 2325 LETDLQASRELTSRLHEEINMKEQKIISLLSGKEEAIQ---VAIAELRQQHDKEIKELEN 2381
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN-QLSCELDDESENTYERIS 386
Q E+ N K + N++ + K N Q +L D + +
Sbjct: 2382 LLSQ----EEEENIVLEEENKKAVDKTNQLMETLKTIKKENIQQKAQL-DSFVKSMSSLQ 2436
Query: 387 LTLDKITNHITYLNTQ-INETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
D+I L + ++ + D QL+ EA + L E+ L+ + L +EN +
Sbjct: 2437 NDRDRIVGDYQQLEERHLSIILEKD--QLIQEAAAENNKLKEEIRGLRSHMDDLNSENAK 2494
Query: 446 LLIE-IQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDD 504
L E IQ N+ +T+ N+ ++ K+ E + EDL
Sbjct: 2495 LDAELIQYREDLNQVITIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRR 2554
Query: 505 VMKQQQKE 512
Q+E
Sbjct: 2555 SFNALQEE 2562
>Z15005-1|CAA78727.1| 2663|Homo sapiens CENP-E protein.
Length = 2663
Score = 62.1 bits (144), Expect = 5e-09
Identities = 82/425 (19%), Positives = 177/425 (41%), Gaps = 28/425 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K V E +N+ +N I L L +L+ + + + ++ +E+E L
Sbjct: 834 KMVLE-ENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQL 892
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTL 168
K E ++ S + V +TE + ++L + ++ + S+ + +K+
Sbjct: 893 K-EQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSD 951
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVD----- 223
+ + N +LRN+++ L+ + NT K+ E+++ + + E D
Sbjct: 952 IHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKDEFQQK 1011
Query: 224 LLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDE--- 280
++ I+ + L+ + + I +L + K L + S I EK++
Sbjct: 1012 MVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKT 1071
Query: 281 NFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLN 340
+ K+ I+M E R +E +++ I+ + + + K E EL ++L + E+L
Sbjct: 1072 DLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKK-EGELSRTCDRLAEVEEKLK 1130
Query: 341 DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLN 400
+ + + + N +++ K N++ L +E +N LTL+ +
Sbjct: 1131 EKSQQLQEKQQQLLNVQEEMSEMQKKINEIE-NLKNELKNK----ELTLEHM-------- 1177
Query: 401 TQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEV 460
ET++ + AQ L E +++ +T++ +LKE ETE L I+ + + +
Sbjct: 1178 ----ETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGYIREIEATGLQT 1233
Query: 461 TLNLK 465
LK
Sbjct: 1234 KEELK 1238
Score = 56.8 bits (131), Expect = 2e-07
Identities = 74/376 (19%), Positives = 165/376 (43%), Gaps = 41/376 (10%)
Query: 86 IAETKHNDLKKLYEDSASELEALKRENIQMHTS------DVMVVPEIIDSLTEVINTLTN 139
I K N++ + +D +ALK +++++ + E ID L +++ T+
Sbjct: 1743 IVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTD 1802
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYN- 198
++++ +++ + + +K +LIT + D+NE + + +E +K +
Sbjct: 1803 KLSNMQK---DLENSNAKLQEKIQELKANEHQLITLKK-DVNETQKKVSEMEQLKKQIKD 1858
Query: 199 ---TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
T ++ E LN A + ++E ++K E NL + RD+
Sbjct: 1859 QSLTLSKLEIENLNLAQELHENLEEMKSVMK-ERDNLRRVEETLKLE----------RDQ 1907
Query: 256 FIANLEEMKT--MLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
+L+E K + ++++L + + K+ +D L EK+ EK I +SD
Sbjct: 1908 LKESLQETKARDLEIQQELKTARMLSKEHKETVDKLREKI-----------SEKTIQISD 1956
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ K ++K++ EL++K ++L QL + + + N++ Q+ F+ + CE
Sbjct: 1957 IQKDLDKSKDELQKKIQELQKKELQLLRVKED-VNMSHKKINEMEQLKKQFEPNYLCKCE 2015
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
+D+ SL +I +I E+ K + Q + ++ IA + + +
Sbjct: 2016 MDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIARDRQNHQVKP 2075
Query: 434 ERLSQLETENKELLIE 449
E+ +L ++ ++ L+E
Sbjct: 2076 EK--RLLSDGQQHLME 2089
Score = 46.4 bits (105), Expect = 2e-04
Identities = 73/399 (18%), Positives = 168/399 (42%), Gaps = 26/399 (6%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEAL--KRENIQMHTSDVMV-VPEIIDSLTEVINT 136
L EK ++ + L K ++ + EAL K + ++ H + + + E + +N
Sbjct: 1333 LNEKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNM 1392
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTL-LDKLITKNETDINELRNSIKYLESVKS 195
E+ + V+ K I I+ L L K + ++ ++ + L+ ++
Sbjct: 1393 KEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQE 1452
Query: 196 EYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
+ +++L E + V K +EE LK+ + L +
Sbjct: 1453 VLQSESDQLKENIKEIVAKHLETEEE---LKVAHCCLKEQEETINELRVNLSEKETEIST 1509
Query: 256 FIANLEEMKTMLVEEKLSEIKEKDENFK-QEIDMLNEKLICDRREFNETMQEKNILLSDL 314
LE + L + K+ EI EK+E ++I + E + + ++F E + K+ L +
Sbjct: 1510 IQKQLEAINDKL-QNKIQEIYEKEEQLNIKQISEVQEN-VNELKQFKEHRKAKDSALQSI 1567
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
K+ + L+E QE++ ++++ + + ++ E + + Q+ + K ++ ++
Sbjct: 1568 ESKMLELTNRLQESQEEIQIMIKEKEEMK----RVQEALQIERDQLKENTK---EIVAKM 1620
Query: 375 DDESENTYERISLTLDKITN----HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI 430
+ E Y+ + +T T I +L Q ETQK N + + ++ + +N+
Sbjct: 1621 KESQEKEYQFLKMTAVNETQEKMCEIEHLKEQF-ETQKL-NLENIETENIRLTQILHENL 1678
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSST 469
E + + E +L +T++ +++ NL+++ T
Sbjct: 1679 ---EEMRSVTKERDDLRSVEETLKVERDQLKENLRETIT 1714
Score = 46.4 bits (105), Expect = 2e-04
Identities = 98/508 (19%), Positives = 204/508 (40%), Gaps = 34/508 (6%)
Query: 25 RLEECYK-EIGQLKSGLQQNVGVGDKTVAELKN-----DEINSMIRQLXXXXXXXXXXXX 78
RL+E + E QLK +++ V +T ELK E I +L
Sbjct: 1449 RLQEVLQSESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKETEIS 1508
Query: 79 XLTEKLTIAETK-HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTL 137
+ ++L K N ++++YE +L + +Q + +++ E + + ++
Sbjct: 1509 TIQKQLEAINDKLQNKIQEIYEKE-EQLNIKQISEVQENVNELKQFKEHRKAKDSALQSI 1567
Query: 138 TNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETDINELRNSIKYLESVKSE 196
+ L E + + K+ +K + + L I +++ N K ES + E
Sbjct: 1568 ESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKE 1627
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL----LQXXXXXXXXXXXXXXXXXA 252
Y + + + ++E+ + K+ +N+ ++
Sbjct: 1628 YQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKE 1687
Query: 253 RDKFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL 310
RD + E +K ++E L E +D ++E+ +++ L +E ET+ + +
Sbjct: 1688 RDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHL----KEHQETIDKLRGI 1743
Query: 311 LSDLSKKVNKTERELEEKQEQL----THLMEQLNDTENNSYKLIENMFNKVSQIASD--F 364
+S+ + +++ +++LE + L + E+L + K + +K+ I S+
Sbjct: 1744 VSEKTNEISNMQKDLEHSNDALKAQDLKIQEELR-IAHMHLKEQQETIDKLRGIVSEKTD 1802
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD 424
K+SN + +L++ + E+I L + + L +NETQK + + KKQI D
Sbjct: 1803 KLSN-MQKDLENSNAKLQEKIQ-ELKANEHQLITLKKDVNETQK--KVSEMEQLKKQIKD 1858
Query: 425 --LTEQNIILKE-RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXX 481
LT + ++ L+Q EN E + + R + V LK
Sbjct: 1859 QSLTLSKLEIENLNLAQELHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKAR 1918
Query: 482 SNEI-EDMKTKVMEWKSQFEDLDDVMKQ 508
EI +++KT M K E +D + ++
Sbjct: 1919 DLEIQQELKTARMLSKEHKETVDKLREK 1946
Score = 43.6 bits (98), Expect = 0.002
Identities = 86/453 (18%), Positives = 194/453 (42%), Gaps = 43/453 (9%)
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEID 152
+LK+ ++ A+ + ++ + IQ++ S + ++ L + + + N L + ++
Sbjct: 650 ELKEKMKELATTYKQMEND-IQLYQSQLEAKKKMQVDLEKELQSAFNEITKLTSL-IDGK 707
Query: 153 LKKNSITKDNISIK-TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
+ K+ + + K T L K + K + LR + L +KS + E+L +++ +
Sbjct: 708 VPKDLLCNLELEGKITDLQKELNKEVEENEALREEVILLSELKSLPSEV-ERLRKEIQDK 766
Query: 212 VDKQNCIQEEVDLLKIEN-------QNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMK 264
++ + I E D L E Q LL+ + D+ N + +
Sbjct: 767 SEELHIITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLH 826
Query: 265 TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
M E+K + E++E +N++++ +E + L ++LS K + + +
Sbjct: 827 -MDFEQKYKMVLEENER-------MNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEK 878
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS----NQLSCELDDESEN 380
E QE+L MEQL + N ++ + + + I + + L+ E DD +
Sbjct: 879 TREVQERLNE-MEQLKEQLENRDSPLQTVEREKTLITEKLQQTLEEVKTLTQEKDD-LKQ 936
Query: 381 TYERISLTLDKITNHI---TYLNTQINETQKN------DNAQLLWEAKKQIADLTEQNII 431
E + + D++ + I +N E +N + + + K +I++ +N+
Sbjct: 937 LQESLQIERDQLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLH 996
Query: 432 LKERLSQLETENKELLIEI---QTVRGSN-EEVTLNLKDSS-TXXXXXXXXXXXXSNEIE 486
++E + + E ++ ++ I Q + N + +T ++KD+ NE++
Sbjct: 997 MEENTGETKDEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQ 1056
Query: 487 DMKTKVMEWKSQFE-DLDDVMK---QQQKELKL 515
M V+ K Q + DL + ++ + Q+EL+L
Sbjct: 1057 QMLESVIAEKEQLKTDLKENIEMTIENQEELRL 1089
Score = 41.5 bits (93), Expect = 0.007
Identities = 39/188 (20%), Positives = 87/188 (46%), Gaps = 13/188 (6%)
Query: 280 ENFKQEIDMLN---EKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM 336
EN + E++ L + L+ D + +E + L + + E + K++Q L+
Sbjct: 494 ENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLI 553
Query: 337 EQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI-SLTLDKITNH 395
++++ +N L+++ + ++ +L E +D+ + E I S L+ I
Sbjct: 554 HEISNLKN----LVKHREVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMD 609
Query: 396 ITYLNTQINETQKN-----DNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEI 450
++Y I + ++ D + +AK++ A L +N+ LKE++ +L T K++ +I
Sbjct: 610 LSYSLESIEDPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDI 669
Query: 451 QTVRGSNE 458
Q + E
Sbjct: 670 QLYQSQLE 677
Score = 41.5 bits (93), Expect = 0.007
Identities = 79/416 (18%), Positives = 167/416 (40%), Gaps = 30/416 (7%)
Query: 127 IDSLTEVINTLTNGFESL--EEVALEIDLK-KNSITK-DNISIKTLLDKLITKNETDINE 182
++SL + L +E L E+ +E+ LK KN + + + + KT D+ + +I+
Sbjct: 500 LNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIH-EISN 558
Query: 183 LRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIEN------QNLLQXX 236
L+N +K+ E + E L D+ +QE +D K+EN +L
Sbjct: 559 LKNLVKHREVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIE 618
Query: 237 XXXXXXXXXXXXXXXARD-KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC 295
A D K + + + ++EK+ E+ + + +I + +L
Sbjct: 619 DPKQMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQLEA 678
Query: 296 DR-------REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
+ +E E L S + KV K E + ++T L ++LN +
Sbjct: 679 KKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDLLCNLELEGKITDLQKELNKEVEENEA 738
Query: 349 LIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQI----N 404
L E + +S++ S +L E+ D+SE + I+ DK+ + + + +++
Sbjct: 739 LREEVI-LLSELKSLPSEVERLRKEIQDKSEELH-IITSEKDKLFSEVVHKESRVQGLLE 796
Query: 405 ETQKNDNAQLLWEAKKQIADLTEQN-----IILKERLSQLETENKELLIEIQTVRGSNEE 459
E K + ++ + D QN + +++ + EN+ + EI + ++
Sbjct: 797 EIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQK 856
Query: 460 VTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+L T + E+++ ++ + K Q E+ D ++ ++E L
Sbjct: 857 FDSSLGALKTELSYKTQELQEKTREVQERLNEMEQLKEQLENRDSPLQTVEREKTL 912
>D10667-1|BAA36971.1| 1052|Homo sapiens smooth muscle myosin heavy
chain protein.
Length = 1052
Score = 61.7 bits (143), Expect = 6e-09
Identities = 80/409 (19%), Positives = 171/409 (41%), Gaps = 34/409 (8%)
Query: 130 LTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE---TDINELRNS 186
L E + T + EE+ + + KK + + ++ L++ + + + ++
Sbjct: 6 LQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 65
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
+ LE E A +KL + A K +++E+ ++ +N L +
Sbjct: 66 MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 125
Query: 247 XXXXXARDKFIANLEEMKTMLVEEKLSEIK---EKDENFKQEIDMLNEKLICDRREFNET 303
++ NL ++K E +SE++ +K+E +QE++ L KL D +F+E
Sbjct: 126 TTNLAEEEEKAKNLTKLKNKH-ESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQ 184
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+ + +++L ++ K E EL Q L L +++ +NN+ K I + +S + D
Sbjct: 185 IADLQAQIAELKMQLAKKEEEL---QAALARLDDEIAQ-KNNALKKIRELEGHISDLQED 240
Query: 364 F--------KISNQ----------LSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
K Q L EL+D ++T + L K +T L ++E
Sbjct: 241 LDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRA-KREQEVTVLKKALDE 299
Query: 406 TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
++ AQ + E +++ A E+ L E+L Q + L QT+ N ++ L+
Sbjct: 300 ETRSHEAQ-VQEMRQKHAQAVEE---LTEQLEQFKRAKANLDKNKQTLEKENADLAGELR 355
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++++++K + + +L+D + + Q E++
Sbjct: 356 VLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVE 404
Score = 50.0 bits (114), Expect = 2e-05
Identities = 93/502 (18%), Positives = 199/502 (39%), Gaps = 41/502 (8%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTE 82
LEE +E + LQ + + +L+ DEI M Q L LT
Sbjct: 69 LEEQLEEEEAARQKLQLEKVTAEAKIKKLE-DEILVMDDQNNKLSKERKLLEERISDLTT 127
Query: 83 KLTIAETKHNDLKKL---YEDSASELEA-LKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L E K +L KL +E SELE LK+E ++ L +
Sbjct: 128 NLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQE---------LEKLKRKLEGDA 178
Query: 139 NGF-ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ F E + ++ +I K + K ++ L +L + +I + N++K + ++
Sbjct: 179 SDFHEQIADLQAQIAELKMQLAKKEEELQAALARL----DDEIAQKNNALKKIRELEGHI 234
Query: 198 NTANEKLFEQL---NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ E L + N A ++ + EE++ LK E ++ L
Sbjct: 235 SDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLK 294
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE-KLICDRREFNETMQEKNILLSD 313
K + V+E + + E ++++ K D+ + +T++++N L+
Sbjct: 295 KALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNK--QTLEKENADLAG 352
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ + + ++E+E K+++L +++L ++ + + +KV K+ N++
Sbjct: 353 ELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVH------KLQNEVESV 406
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNII 431
+E + I L D + L++Q+ +TQ+ + + ++ L E+
Sbjct: 407 TGMLNEAEGKAIKLAKD-----VASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 461
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
L+++L + + L I T+ + L+D ++ EIE++ +
Sbjct: 462 LQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQ 521
Query: 492 VMEWKSQFEDLDDVMKQQQKEL 513
E + ++ L+ + Q+EL
Sbjct: 522 YEEKAAAYDKLEKTKNRLQQEL 543
Score = 44.8 bits (101), Expect = 7e-04
Identities = 78/424 (18%), Positives = 177/424 (41%), Gaps = 47/424 (11%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNI 163
E+ LK+ + S V E+ + + LT E + +D K ++ K+N
Sbjct: 289 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 348
Query: 164 SIKTLLDKLITKNETDINELRNSIK-YLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEE 221
+ L +++ + + ++ + ++ ++ ++S+ + E+ +LN+ V K QN ++
Sbjct: 349 DLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESV 406
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN 281
+L N + + + E + + V KL +++E+ +
Sbjct: 407 TGML-----NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 461
Query: 282 FKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN---KTERELEEKQEQLTHLMEQ 338
+ ++D E ++ + NI LSD KK+ T LEE +++ +E
Sbjct: 462 LQDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 517
Query: 339 LN---DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE--NTYERISLTLDKIT 393
L + + +Y +E N++ Q D + +LD++ + + E+ D++
Sbjct: 518 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVV------DLDNQRQLVSNLEKKQRKFDQLL 571
Query: 394 NHITYLNTQINETQKNDNAQLLWEAKK--QIADLTEQNIILKERLSQLETENKELLIEIQ 451
++++ + + A+ + K +A E+ + KE +LE NK L E++
Sbjct: 572 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE---ELERTNKMLKAEME 628
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ S ++V N+ + ++T++ E K+Q E+L+D + Q +
Sbjct: 629 DLVSSKDDVGKNVHELEKSKRA--------------LETQMEEMKTQLEELEDEL-QASE 673
Query: 512 ELKL 515
+ KL
Sbjct: 674 DAKL 677
Score = 41.9 bits (94), Expect = 0.005
Identities = 79/402 (19%), Positives = 167/402 (41%), Gaps = 46/402 (11%)
Query: 130 LTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKY 189
L + ++ L N ES+ + E + K + KD S+ + L + + + N
Sbjct: 392 LNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTK 451
Query: 190 LESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXX 249
L ++ E N+ ++L E++ KQN ++ + L I+ L
Sbjct: 452 LRQLEEERNSLQDQLDEEMEA---KQN-LERHISTLNIQ---LSDSKKKLQDFASTVEAL 504
Query: 250 XXARDKFIANLEEMKTMLVEEKLSEIK--EKDEN-FKQEIDML-----NEKLICD----- 296
+ +F +E + T EEK + EK +N +QE+D L N++ +
Sbjct: 505 EEGKKRFQKEIENL-TQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKK 563
Query: 297 RREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK 356
+R+F++ + E+ + S + + ++ E E EK+ + L L + +L NK
Sbjct: 564 QRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEEL--ERTNK 621
Query: 357 VSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQI----NETQKNDNA 412
+ + + +S++ DD +N +E + + + + + TQ+ +E Q +++A
Sbjct: 622 MLKAEMEDLVSSK-----DDVGKNVHE-LEKSKRALETQMEEMKTQLEELEDELQASEDA 675
Query: 413 QLLWEAKKQI------ADL---TEQN----IILKERLSQLETENKELLIEIQTVRGSNEE 459
+L E Q DL EQN L+ +L + ETE ++ E + ++
Sbjct: 676 KLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERNERALAAAAKKK 735
Query: 460 VTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ +LKD ++ ++ ++ +++ + ED
Sbjct: 736 LEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 777
Score = 39.1 bits (87), Expect = 0.037
Identities = 70/404 (17%), Positives = 149/404 (36%), Gaps = 19/404 (4%)
Query: 48 DKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEA 107
D+ AE + E ++ T K+ AE + DL +D +
Sbjct: 586 DRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME--DLVSSKDDVGKNVHE 643
Query: 108 LKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKD------ 161
L++ + T + E+ L E+ + L ++ + + + K +D
Sbjct: 644 LEKSKRALETQ----MEEMKTQLEELEDELQASEDAKLRLEVNMQALKGQFERDLQARDE 699
Query: 162 -NISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQE 220
N + L + + + ET++ + RN + K + + L Q ++A+ + +
Sbjct: 700 QNEEKRRQLQRQLHEYETELEDERNERALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 759
Query: 221 EVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDE 280
++ L+ + ++ + +K +LE M ++E L+ + +
Sbjct: 760 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEA-DLMQLQEDLAAAERARK 818
Query: 281 NFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLN 340
E + L E+L N EK L ++ + E ELEE+Q + + +++
Sbjct: 819 QADLEKEELAEELASSLSGRNALQDEKR----RLEARIAQLEEELEEEQGNMEAMSDRVR 874
Query: 341 DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLN 400
+ +L + + S + QL + + +E K + I L
Sbjct: 875 KATQQAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALE 934
Query: 401 TQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENK 444
+I + ++ Q E + L +++ LKE L Q+E E K
Sbjct: 935 AKIAQLEEQVE-QEAREKQAATKSLKQKDKKLKEILLQVEDERK 977
Score = 36.7 bits (81), Expect = 0.20
Identities = 43/237 (18%), Positives = 98/237 (41%), Gaps = 15/237 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E D+ +L+ + E + + + E+L E+L +++ +N +Q+E L+ + Q
Sbjct: 800 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE---ARIAQLE 856
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICD 296
K E++ L E+ +K+E+ +Q+++ N++L
Sbjct: 857 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATER--STAQKNESARQQLERQNKELRSK 914
Query: 297 RREFNETMQEK-NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKL---IEN 352
E ++ K ++ L K+ + E ++E++ + + L + ++ +E+
Sbjct: 915 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 974
Query: 353 MFNKVSQIASDFKISN----QLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
Q + N QL +L +E+E +RI+ K+ + T+ NE
Sbjct: 975 ERKMAEQYKEQAEKGNARVKQLKRQL-EEAEEESQRINANRRKLQRELDEA-TESNE 1029
Score = 35.5 bits (78), Expect = 0.46
Identities = 44/246 (17%), Positives = 108/246 (43%), Gaps = 20/246 (8%)
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
L E E++E +Q++ + EK+ + + + ++++ +++ D + K++K + LEE+
Sbjct: 69 LEEQLEEEEAARQKLQL--EKVTAEAKI--KKLEDEILVMDDQNNKLSKERKLLEERISD 124
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDK 391
LT + + + N KL + +S++ ++ + +++S E++ K
Sbjct: 125 LTTNLAEEEEKAKNLTKLKNKHESMISEL--------EVRLKKEEKSRQELEKLKR---K 173
Query: 392 ITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
+ + + QI + Q AQ+ E K Q+A E+ RL + L +I+
Sbjct: 174 LEGDASDFHEQIADLQ----AQIA-ELKMQLAKKEEELQAALARLDDEIAQKNNALKKIR 228
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ G ++ +L E+E +KT++ + ++ ++++
Sbjct: 229 ELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ 288
Query: 512 ELKLGK 517
E+ + K
Sbjct: 289 EVTVLK 294
>M97501-1|AAA35693.1| 1392|Homo sapiens cytoplasmic linker protein-170
alpha-2 protein.
Length = 1392
Score = 61.3 bits (142), Expect = 8e-09
Identities = 109/519 (21%), Positives = 201/519 (38%), Gaps = 33/519 (6%)
Query: 10 ANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXX 69
A E + I A E+ KE LKS L+ +A K+ ++
Sbjct: 533 AREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAM 592
Query: 70 XXXXXXXXXXL-TEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIID 128
L TE AE K ++K+ D E+E L+ + + + +
Sbjct: 593 EELKVSFSKGLGTETAEFAELK-TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRA 651
Query: 129 SLTEVINTLTNGFESLEEVALEIDLKKNS-ITKDNISIKTLLDKLITKNETDINELR--N 185
L +VI N SLE + ++D ++ + + ++ L + I E ++ + +
Sbjct: 652 KLMKVIKEKEN---SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNE 708
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
K +++ S+ EKL + +A+ K + E +K Q L
Sbjct: 709 QTKVIDNFTSQLKATEEKLLDL--DALRKAS--SEGKSEMKKLRQQLEAAEKQIKHLEIE 764
Query: 246 XXXXXXARDKFIANLE--EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRRE---F 300
L+ E+K ++E LSE+ + E ++E+ +L EK E
Sbjct: 765 KNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSV 824
Query: 301 NETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
+MQE L ++ N +LE+ +E L + + + + +LI+ + I
Sbjct: 825 QRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDI 884
Query: 361 ASDFKISNQLSCEL---DDE---SENTYERISLTLDKITNHITYLNTQINE-TQKNDNAQ 413
A K+S S +L +DE E E + L L K + ++L I + T K + +Q
Sbjct: 885 AEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQ 944
Query: 414 LLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
EA K+ E+ L+ +LS LE + + + Q ++ E T ++ T
Sbjct: 945 --QEAAKK---HEEEKKELERKLSDLEKKMETSHNQCQELKARYERAT---SETKTKHEE 996
Query: 474 XXXXXXXXSNEIED-MKTKVMEWKSQFEDLDDVMKQQQK 511
+ ED +K E ++L+++ KQ +K
Sbjct: 997 ILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEK 1035
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/434 (18%), Positives = 181/434 (41%), Gaps = 23/434 (5%)
Query: 82 EKLTIAETK-HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNG 140
E+L A+ K ND+ ++ + S L + N ++ + V E+ LT+ +
Sbjct: 871 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE-RDVEELQLKLTKANENASFL 929
Query: 141 FESLEEVALEIDLKKNSITKDNISIKTLLDKLIT----KNETDINELRNSIKYLESVKSE 196
+S+E++ ++ + + K + K L++ ++ K ET N+ + E SE
Sbjct: 930 QKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSE 989
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
T +E++ + L + ++++ + EN LLQ A D
Sbjct: 990 TKTKHEEILQNLQKTLLDT---EDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDA- 1045
Query: 257 IANLEEMKTMLVEE--KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
+ +E+M E L + K+ + + E+D L E + + E N++ + LL+
Sbjct: 1046 MQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKE----LLTVE 1101
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++K+ + +E+E ++ +QL+ + + KL E + ++ S K+ + S L
Sbjct: 1102 NQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSV-L 1160
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNIIL 432
+++ +R S + L I+ T + L + + ++ L +N
Sbjct: 1161 NNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA 1220
Query: 433 KER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSS-TXXXXXXXXXXXXSNEIEDM 488
K + LE++ +L ++++ + +E L SS ++I+ +
Sbjct: 1221 KSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFL 1280
Query: 489 KTKVMEWKSQFEDL 502
+ +++ + + +DL
Sbjct: 1281 NSVIVDLQRKNQDL 1294
Score = 48.0 bits (109), Expect = 8e-05
Identities = 89/448 (19%), Positives = 180/448 (40%), Gaps = 34/448 (7%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L + + K N+ K+ ++ S+L+A + + + D+ + + + L
Sbjct: 697 KELEVLQAKCNEQTKVIDNFTSQLKATEEKLL-----DLDALRKASSEGKSEMKKLRQQL 751
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL-ESVKSEYNTA 200
E+ E+ ++++KN+ + SI L K T++ E + + + E+++ E
Sbjct: 752 EAAEKQIKHLEIEKNAESSKASSITRELQGRELKL-TNLQENLSEVSQVKETLEKELQIL 810
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
EK E AV Q +QE V+ L +Q Q KF
Sbjct: 811 KEKFAEASEEAVSVQRSMQETVNKL---HQKEEQFNMLSSDLEKLRENLADMEAKFREKD 867
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E EE+L + KEK EN EI ++ + N+ ++ K + +L K+ K
Sbjct: 868 ER------EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTK 921
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
Q+ + + + ++ + K E ++ + SD + + S E +
Sbjct: 922 ANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKA 981
Query: 381 TYER-ISLTLDKITNHITYLNTQINETQ------KNDNAQLLWE-------AKKQIADLT 426
YER S T K + L + +T+ + +N+ LL E A+K A T
Sbjct: 982 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQT 1041
Query: 427 EQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIE 486
++ + + + Q+ E E L ++ + +N ++ N D+ S E+
Sbjct: 1042 AEDAM--QIMEQMTKEKTETLASLEDTKQTNAKLQ-NELDTLKENNLKNVEELNKSKELL 1098
Query: 487 DMKT-KVMEWKSQFEDLDDVMKQQQKEL 513
++ K+ E++ + E L Q+ ++L
Sbjct: 1099 TVENQKMEEFRKEIETLKQAAAQKSQQL 1126
>X64838-1|CAA46050.1| 1427|Homo sapiens restin protein.
Length = 1427
Score = 60.5 bits (140), Expect = 1e-08
Identities = 101/472 (21%), Positives = 183/472 (38%), Gaps = 29/472 (6%)
Query: 10 ANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXX 69
A E + I A E+ KE LKS L+ +A K+ ++
Sbjct: 568 AREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAM 627
Query: 70 XXXXXXXXXXL-TEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIID 128
L TE AE K ++K+ D E+E L+ + + + +
Sbjct: 628 EELKVSFSKGLGTETAEFAELK-TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRA 686
Query: 129 SLTEVINTLTNGFESLEEVALEIDLKKNS-ITKDNISIKTLLDKLITKNETDINELR--N 185
L +VI N SLE + ++D ++ + + ++ L + I E ++ + +
Sbjct: 687 KLMKVIKEKEN---SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNE 743
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
K +++ S+ EKL + +A+ K + E +K Q L
Sbjct: 744 QTKVIDNFTSQLKATEEKLLDL--DALRKAS--SEGKSEMKKLRQQLEAAEKQIKHLEIE 799
Query: 246 XXXXXXARDKFIANLE--EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRRE---F 300
L+ E+K ++E LSE+ + E ++E+ +L EK E
Sbjct: 800 KNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSV 859
Query: 301 NETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
+MQE L ++ N +LE+ +E L + + + + +LI+ + I
Sbjct: 860 QRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDI 919
Query: 361 ASDFKISNQLSCEL---DDE---SENTYERISLTLDKITNHITYLNTQINE-TQKNDNAQ 413
A K+S S +L +DE E E + L L K + ++L I + T K + +Q
Sbjct: 920 AEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQ 979
Query: 414 LLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
EA K+ E+ L+ +LS LE + + + Q ++ E T K
Sbjct: 980 --QEAAKK---HEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETK 1026
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/434 (18%), Positives = 181/434 (41%), Gaps = 23/434 (5%)
Query: 82 EKLTIAETK-HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNG 140
E+L A+ K ND+ ++ + S L + N ++ + V E+ LT+ +
Sbjct: 906 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE-RDVEELQLKLTKANENASFL 964
Query: 141 FESLEEVALEIDLKKNSITKDNISIKTLLDKLIT----KNETDINELRNSIKYLESVKSE 196
+S+E++ ++ + + K + K L++ ++ K ET N+ + E SE
Sbjct: 965 QKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSE 1024
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
T +E++ + L + ++++ + EN LLQ A D
Sbjct: 1025 TKTKHEEILQNLQKTLLDT---EDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDA- 1080
Query: 257 IANLEEMKTMLVEE--KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
+ +E+M E L + K+ + + E+D L E + + E N++ + LL+
Sbjct: 1081 MQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKE----LLTVE 1136
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++K+ + +E+E ++ +QL+ + + KL E + ++ S K+ + S L
Sbjct: 1137 NQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSV-L 1195
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNIIL 432
+++ +R S + L I+ T + L + + ++ L +N
Sbjct: 1196 NNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA 1255
Query: 433 KER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSS-TXXXXXXXXXXXXSNEIEDM 488
K + LE++ +L ++++ + +E L SS ++I+ +
Sbjct: 1256 KSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFL 1315
Query: 489 KTKVMEWKSQFEDL 502
+ +++ + + +DL
Sbjct: 1316 NSVIVDLQRKNQDL 1329
Score = 47.6 bits (108), Expect = 1e-04
Identities = 87/446 (19%), Positives = 179/446 (40%), Gaps = 30/446 (6%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L + + K N+ K+ ++ S+L+A + + + D+ + + + L
Sbjct: 732 KELEVLQAKCNEQTKVIDNFTSQLKATEEKLL-----DLDALRKASSEGKSEMKKLRQQL 786
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL-ESVKSEYNTA 200
E+ E+ ++++KN+ + SI L K T++ E + + + E+++ E
Sbjct: 787 EAAEKQIKHLEIEKNAESSKASSITRELQGRELKL-TNLQENLSEVSQVKETLEKELQIL 845
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
EK E AV Q +QE V+ L +Q Q KF
Sbjct: 846 KEKFAEASEEAVSVQRSMQETVNKL---HQKEEQFNMLSSDLEKLRENLADMEAKFREKD 902
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E EE+L + KEK EN EI ++ + N+ ++ K + +L K+ K
Sbjct: 903 ER------EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTK 956
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
Q+ + + + ++ + K E ++ + SD + + S E +
Sbjct: 957 ANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKA 1016
Query: 381 TYER-ISLTLDKITNHITYLNTQINETQ------KNDNAQLLWEAK--KQIADLTEQNII 431
YER S T K + L + +T+ + +N+ LL E + ++ AD +
Sbjct: 1017 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQT 1076
Query: 432 LKER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDM 488
++ + Q+ E E L ++ + +N ++ N D+ S E+ +
Sbjct: 1077 AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ-NELDTLKENNLKNVEELNKSKELLTV 1135
Query: 489 KT-KVMEWKSQFEDLDDVMKQQQKEL 513
+ K+ E++ + E L Q+ ++L
Sbjct: 1136 ENQKMEEFRKEIETLKQAAAQKSQQL 1161
>BC126305-1|AAI26306.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 60.5 bits (140), Expect = 1e-08
Identities = 101/472 (21%), Positives = 183/472 (38%), Gaps = 29/472 (6%)
Query: 10 ANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXX 69
A E + I A E+ KE LKS L+ +A K+ ++
Sbjct: 579 AREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAM 638
Query: 70 XXXXXXXXXXL-TEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIID 128
L TE AE K ++K+ D E+E L+ + + + +
Sbjct: 639 EELKVSFSKGLGTETAEFAELK-TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRA 697
Query: 129 SLTEVINTLTNGFESLEEVALEIDLKKNS-ITKDNISIKTLLDKLITKNETDINELR--N 185
L +VI N SLE + ++D ++ + + ++ L + I E ++ + +
Sbjct: 698 KLMKVIKEKEN---SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNE 754
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
K +++ S+ EKL + +A+ K + E +K Q L
Sbjct: 755 QTKVIDNFTSQLKATEEKLLDL--DALRKAS--SEGKSEMKKLRQQLEAAEKQIKHLEIE 810
Query: 246 XXXXXXARDKFIANLE--EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRRE---F 300
L+ E+K ++E LSE+ + E ++E+ +L EK E
Sbjct: 811 KNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSV 870
Query: 301 NETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
+MQE L ++ N +LE+ +E L + + + + +LI+ + I
Sbjct: 871 QRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDI 930
Query: 361 ASDFKISNQLSCEL---DDE---SENTYERISLTLDKITNHITYLNTQINE-TQKNDNAQ 413
A K+S S +L +DE E E + L L K + ++L I + T K + +Q
Sbjct: 931 AEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQ 990
Query: 414 LLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
EA K+ E+ L+ +LS LE + + + Q ++ E T K
Sbjct: 991 --QEAAKK---HEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETK 1037
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/434 (18%), Positives = 181/434 (41%), Gaps = 23/434 (5%)
Query: 82 EKLTIAETK-HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNG 140
E+L A+ K ND+ ++ + S L + N ++ + V E+ LT+ +
Sbjct: 917 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE-RDVEELQLKLTKANENASFL 975
Query: 141 FESLEEVALEIDLKKNSITKDNISIKTLLDKLIT----KNETDINELRNSIKYLESVKSE 196
+S+E++ ++ + + K + K L++ ++ K ET N+ + E SE
Sbjct: 976 QKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSE 1035
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
T +E++ + L + ++++ + EN LLQ A D
Sbjct: 1036 TKTKHEEILQNLQKTLLDT---EDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDA- 1091
Query: 257 IANLEEMKTMLVEE--KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
+ +E+M E L + K+ + + E+D L E + + E N++ + LL+
Sbjct: 1092 MQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKE----LLTVE 1147
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++K+ + +E+E ++ +QL+ + + KL E + ++ S K+ + S L
Sbjct: 1148 NQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSV-L 1206
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNIIL 432
+++ +R S + L I+ T + L + + ++ L +N
Sbjct: 1207 NNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA 1266
Query: 433 KER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSS-TXXXXXXXXXXXXSNEIEDM 488
K + LE++ +L ++++ + +E L SS ++I+ +
Sbjct: 1267 KSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFL 1326
Query: 489 KTKVMEWKSQFEDL 502
+ +++ + + +DL
Sbjct: 1327 NSVIVDLQRKNQDL 1340
Score = 47.6 bits (108), Expect = 1e-04
Identities = 87/446 (19%), Positives = 179/446 (40%), Gaps = 30/446 (6%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L + + K N+ K+ ++ S+L+A + + + D+ + + + L
Sbjct: 743 KELEVLQAKCNEQTKVIDNFTSQLKATEEKLL-----DLDALRKASSEGKSEMKKLRQQL 797
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL-ESVKSEYNTA 200
E+ E+ ++++KN+ + SI L K T++ E + + + E+++ E
Sbjct: 798 EAAEKQIKHLEIEKNAESSKASSITRELQGRELKL-TNLQENLSEVSQVKETLEKELQIL 856
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
EK E AV Q +QE V+ L +Q Q KF
Sbjct: 857 KEKFAEASEEAVSVQRSMQETVNKL---HQKEEQFNMLSSDLEKLRENLADMEAKFREKD 913
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E EE+L + KEK EN EI ++ + N+ ++ K + +L K+ K
Sbjct: 914 ER------EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTK 967
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
Q+ + + + ++ + K E ++ + SD + + S E +
Sbjct: 968 ANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKA 1027
Query: 381 TYER-ISLTLDKITNHITYLNTQINETQ------KNDNAQLLWEAK--KQIADLTEQNII 431
YER S T K + L + +T+ + +N+ LL E + ++ AD +
Sbjct: 1028 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQT 1087
Query: 432 LKER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDM 488
++ + Q+ E E L ++ + +N ++ N D+ S E+ +
Sbjct: 1088 AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ-NELDTLKENNLKNVEELNKSKELLTV 1146
Query: 489 KT-KVMEWKSQFEDLDDVMKQQQKEL 513
+ K+ E++ + E L Q+ ++L
Sbjct: 1147 ENQKMEEFRKEIETLKQAAAQKSQQL 1172
>BC117209-1|AAI17210.1| 1438|Homo sapiens CLIP1 protein protein.
Length = 1438
Score = 59.3 bits (137), Expect = 3e-08
Identities = 109/520 (20%), Positives = 204/520 (39%), Gaps = 35/520 (6%)
Query: 10 ANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXX 69
A E + I A E+ KE LKS L+ +A K+ ++
Sbjct: 579 AREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAM 638
Query: 70 XXXXXXXXXXL-TEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIID 128
L TE AE K ++K+ D E+E L+ + + + +
Sbjct: 639 EELKVSFSKGLGTETAEFAELK-TQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRA 697
Query: 129 SLTEVINTLTNGFESLEEVALEIDLKKNS-ITKDNISIKTLLDKLITKNETDINELR--N 185
L +VI N SLE + ++D ++ + + ++ L + I E ++ + +
Sbjct: 698 KLMKVIKEKEN---SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNE 754
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
K +++ S+ EKL + +A+ K + E +K Q L
Sbjct: 755 QTKVIDNFTSQLKATEEKLLDL--DALRKAS--SEGKSEMKKLRQQLEAAEKQIKHLEIE 810
Query: 246 XXXXXXARDKFIANLE--EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRRE---F 300
L+ E+K ++E LSE+ + E ++E+ +L EK E
Sbjct: 811 KNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSV 870
Query: 301 NETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
+MQE L ++ N +LE+ +E L + + + + +LI+ + I
Sbjct: 871 QRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDI 930
Query: 361 ASDFKIS----NQLSCELDDE---SENTYERISLTLDKITNHITYLNTQINE-TQKNDNA 412
A K+S +QL+ +++DE E E + L L K + ++L I + T K + +
Sbjct: 931 AEIMKMSGDNPSQLT-KMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQS 989
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
Q EA K+ E+ L+ +LS LE + + + Q ++ E T ++ T
Sbjct: 990 Q--QEAAKK---HEEEKKELERKLSDLEKKMETSHNQCQELKARYERAT---SETKTKHE 1041
Query: 473 XXXXXXXXXSNEIED-MKTKVMEWKSQFEDLDDVMKQQQK 511
+ ED +K E ++L+++ KQ +K
Sbjct: 1042 EILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEK 1081
Score = 54.0 bits (124), Expect = 1e-06
Identities = 79/434 (18%), Positives = 181/434 (41%), Gaps = 23/434 (5%)
Query: 82 EKLTIAETK-HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNG 140
E+L A+ K ND+ ++ + S L + N ++ + V E+ LT+ +
Sbjct: 917 EQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKE-RDVEELQLKLTKANENASFL 975
Query: 141 FESLEEVALEIDLKKNSITKDNISIKTLLDKLIT----KNETDINELRNSIKYLESVKSE 196
+S+E++ ++ + + K + K L++ ++ K ET N+ + E SE
Sbjct: 976 QKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSE 1035
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
T +E++ + L + ++++ + EN LLQ A D
Sbjct: 1036 TKTKHEEILQNLQKTLLDT---EDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDA- 1091
Query: 257 IANLEEMKTMLVEE--KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
+ +E+M E L + K+ + + E+D L E + + E N++ + LL+
Sbjct: 1092 MQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKE----LLTVE 1147
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++K+ + +E+E ++ +QL+ + + KL E + ++ S K+ + S L
Sbjct: 1148 NQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSV-L 1206
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNIIL 432
+++ +R S + L I+ T + L + + ++ L +N
Sbjct: 1207 NNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA 1266
Query: 433 KER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSS-TXXXXXXXXXXXXSNEIEDM 488
K + LE++ +L ++++ + +E L SS ++I+ +
Sbjct: 1267 KSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFL 1326
Query: 489 KTKVMEWKSQFEDL 502
+ +++ + + +DL
Sbjct: 1327 NSVIVDLQRKNQDL 1340
Score = 47.6 bits (108), Expect = 1e-04
Identities = 89/448 (19%), Positives = 180/448 (40%), Gaps = 34/448 (7%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L + + K N+ K+ ++ S+L+A + + + D+ + + + L
Sbjct: 743 KELEVLQAKCNEQTKVIDNFTSQLKATEEKLL-----DLDALRKASSEGKSEMKKLRQQL 797
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL-ESVKSEYNTA 200
E+ E+ ++++KN+ + SI L K T++ E + + + E+++ E
Sbjct: 798 EAAEKQIKHLEIEKNAESSKASSITRELQGRELKL-TNLQENLSEVSQVKETLEKELQIL 856
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
EK E AV Q +QE V+ L +Q Q KF
Sbjct: 857 KEKFAEASEEAVSVQRSMQETVNKL---HQKEEQFNMLSSDLEKLRENLADMEAKFREKD 913
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E EE+L + KEK EN EI ++ + N+ ++ K + +L K+ K
Sbjct: 914 ER------EEQLIKAKEKLENDIAEIMKMSGDNPSQLTKMNDELRLKERDVEELQLKLTK 967
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
Q+ + + + ++ + K E ++ + SD + + S E +
Sbjct: 968 ANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKA 1027
Query: 381 TYER-ISLTLDKITNHITYLNTQINETQ------KNDNAQLLWE-------AKKQIADLT 426
YER S T K + L + +T+ + +N+ LL E A+K A T
Sbjct: 1028 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQAEKAKAAQT 1087
Query: 427 EQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIE 486
++ + + + Q+ E E L ++ + +N ++ N D+ S E+
Sbjct: 1088 AEDAM--QIMEQMTKEKTETLASLEDTKQTNAKLQ-NELDTLKENNLKNVEELNKSKELL 1144
Query: 487 DMKT-KVMEWKSQFEDLDDVMKQQQKEL 513
++ K+ E++ + E L Q+ ++L
Sbjct: 1145 TVENQKMEEFRKEIETLKQAAAQKSQQL 1172
>AF111782-1|AAD29948.1| 1938|Homo sapiens myosin heavy chain protein.
Length = 1938
Score = 59.3 bits (137), Expect = 3e-08
Identities = 94/465 (20%), Positives = 187/465 (40%), Gaps = 41/465 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEV-------I 134
E+L +E + +L++ E L+ + +Q T ++M E + L + +
Sbjct: 865 EELARSEARRKELEEKMVSLLQEKNDLQLQ-VQSETENLMDAEERCEGLIKSKILLEAKV 923
Query: 135 NTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYLE 191
LT E EE+ E+ KK ++ S+K +D L +TK E + + N +K L
Sbjct: 924 KELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNL- 982
Query: 192 SVKSEYNTANEKLFEQLNNAVDK-QNCIQEEVDLLKIEN---QNLLQXXXXXXXXXXXXX 247
SE TA E+ +L Q Q+ +D L++E L++
Sbjct: 983 ---SEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLE 1039
Query: 248 XXXXARDKFIANLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQ 305
K A+LE K L + K+S+ D EN KQ+I+ +K + + +
Sbjct: 1040 GSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQARID 1099
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQL-------THLMEQLNDTENNSYKLIENMFNKVS 358
++ + KK+ + + +EE +E++ + +Q +D ++ E +
Sbjct: 1100 DEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEASG 1159
Query: 359 QIASDFKISNQLSCELD------DESENTYERISLTL-DKITNHITYLNTQINETQ--KN 409
++ +++ + E +E+ +E + TL K + + L QI+ Q K
Sbjct: 1160 ATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRVKQ 1219
Query: 410 DNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSST 469
+ E K +I D+ L + S +E + + + ++ +E+ T + D +
Sbjct: 1220 KLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQTQLIHDLNM 1279
Query: 470 XXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
S+ +E+ ++ + SQ + QQ +ELK
Sbjct: 1280 QKARLQTQNGELSHRVEEKESLI----SQLTKSKQALTQQLEELK 1320
Score = 54.4 bits (125), Expect = 9e-07
Identities = 100/536 (18%), Positives = 208/536 (38%), Gaps = 42/536 (7%)
Query: 13 ENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKND---EINSMIRQLXXX 69
+N+ + A + + + KE L+ QQ + D V E K + +IN+ + Q
Sbjct: 980 KNLSEEMTALEENISKLTKEKKSLQEAHQQTLD--DLQVEEDKVNGLIKINAKLEQQTDD 1037
Query: 70 XXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELE--------ALKRENIQMHTSDVM 121
L L A+ K K+ ++S +LE LK++ ++
Sbjct: 1038 LEGSLEQEKKLRADLERAKRKLEGDLKMSQESIMDLENEKQQIEEKLKKKEFELSQLQAR 1097
Query: 122 VVPEIIDSLT--EVINTLTNGFESLEE-------VALEIDLKKNSITKDNISIKTLLDKL 172
+ E + SL + I L E LEE + +I+ +++ + ++ I L++
Sbjct: 1098 IDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLEEA 1157
Query: 173 --ITKNETDINELRNS-IKYLESVKSEYNTANEKLFEQLNNA-VDKQNCIQEEVDLLKIE 228
T + ++N+ R + + + E +E L D + E++D L+
Sbjct: 1158 SGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKQADSVAELGEQIDNLQRV 1217
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQ---E 285
Q L + A K +N+E VE++ SEIK KDE Q +
Sbjct: 1218 KQKLEKEKSELKMEIDDMASNIEALSKSKSNIERT-CRTVEDQFSEIKAKDEQQTQLIHD 1276
Query: 286 IDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN 345
++M +L E + ++EK L+S L+K ++LEE + Q ME+ +N
Sbjct: 1277 LNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQ----MEEETKAKNA 1332
Query: 346 SYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
+++ + + ++ + EL ++ K ++ E
Sbjct: 1333 MAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEE 1392
Query: 406 TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ-------TVRGSNE 458
+K AQ L EA+++ + L++ +L+ E ++L+ +++ T+
Sbjct: 1393 AKKK-LAQRLQEAEEKTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQR 1451
Query: 459 EVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
L + E + T++ + ++ +E++ D ++ ++E K
Sbjct: 1452 NFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENK 1507
Score = 44.0 bits (99), Expect = 0.001
Identities = 68/327 (20%), Positives = 136/327 (41%), Gaps = 24/327 (7%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKND-EINSMIR--QLXXXXXXXXXXXXXLTE 82
L E Y+E + K+ LQ+ + + VA+ K E +++ R +L E
Sbjct: 1347 LREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEELEEAKKKLAQRLQEAEE 1406
Query: 83 KLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFE 142
K A +K L+K + E+E L R+ + HT+ + L +
Sbjct: 1407 KTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTA----CATLDKKQRNFDKVLAEWKQ 1462
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
L+E E++ + K++ S+ T L K+ E +++L + ++++ E + E
Sbjct: 1463 KLDESQAELEAAQ----KESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTE 1518
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
++ E N + E+ L + ++ LQ R + L +
Sbjct: 1519 QIAETGKNLQEA-----EKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQL--ELSQ 1571
Query: 263 MKTML---VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK--- 316
+K+ L V EK EI++ N ++ + L L + R N+ ++ K + DL++
Sbjct: 1572 VKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEI 1631
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTE 343
++ + R++ E Q L + QL D++
Sbjct: 1632 QLGHSNRQMAETQRHLRTVQGQLKDSQ 1658
Score = 38.3 bits (85), Expect = 0.065
Identities = 66/370 (17%), Positives = 155/370 (41%), Gaps = 22/370 (5%)
Query: 161 DNIS-IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN---EKLFEQLNNAVDKQN 216
DN+ +K L+K ++ + +I+++ ++I+ L KS E F ++ ++Q
Sbjct: 1212 DNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKAKDEQQT 1271
Query: 217 CIQEEVDLLK--IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSE 274
+ ++++ K ++ QN + ++ LEE+K + EE ++
Sbjct: 1272 QLIHDLNMQKARLQTQNG-ELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEETKAK 1330
Query: 275 --IKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQL 332
+ ++ + + D+L E+ ++ E + + S++++ K E + ++ E+L
Sbjct: 1331 NAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWKTKYETDAIQRTEEL 1390
Query: 333 THLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD---ESENTYERISLTL 389
++L + + E +K + + K +L E++D + E ++ + TL
Sbjct: 1391 EEAKKKLAQRLQEAEEKTETANSKCASLE---KTKQRLQGEVEDLMRDLERSHTACA-TL 1446
Query: 390 DKITNHITYLNTQINETQKNDNAQL---LWEAKKQIADLTEQNIILKERLSQLET---EN 443
DK + + + + A+L E++ +L + +E + QLET EN
Sbjct: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN 1506
Query: 444 KELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLD 503
K L EI + E NL+++ +E+++ + +S+ +
Sbjct: 1507 KNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQ 1566
Query: 504 DVMKQQQKEL 513
+ Q + EL
Sbjct: 1567 LELSQVKSEL 1576
Score = 33.1 bits (72), Expect = 2.4
Identities = 80/439 (18%), Positives = 169/439 (38%), Gaps = 28/439 (6%)
Query: 32 EIGQLKSGLQQNVGVGDKTVAELKN--DEINSMIRQLXXXXXXXXXXXXXLTEKLTIAET 89
E+G+ LQ+ +K +ELK D++ S I L + ++ + +
Sbjct: 1206 ELGEQIDNLQRVKQKLEKEKSELKMEIDDMASNIEALSKSKSNIERTCRTVEDQFSEIKA 1265
Query: 90 KHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVAL 149
K +L D + L+ +N ++ + V +I LT+ LT + LEE+
Sbjct: 1266 KDEQQTQLIHDLNMQKARLQTQNGEL-SHRVEEKESLISQLTKSKQALT---QQLEELKR 1321
Query: 150 EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLN 209
+++ + K + + + D + LR + + K+E A K
Sbjct: 1322 QME--------EETKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKA----- 1368
Query: 210 NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML-- 267
N+ Q + E D ++ + L + + A+LE+ K L
Sbjct: 1369 NSEVAQWKTKYETDAIQ-RTEELEEAKKKLAQRLQEAEEKTETANSKCASLEKTKQRLQG 1427
Query: 268 -VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
VE+ + ++ E+ +D E+ + + E L K+ EL
Sbjct: 1428 EVEDLMRDL-ERSHTACATLDKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELF 1486
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERIS 386
+ + +++QL + L E + + QIA K + Q + + E +
Sbjct: 1487 KMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGK-NLQEAEKTKKLVEQEKSDLQ 1545
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
+ L+++ + + ++I Q + +Q+ E +++ + E+ LK R SQ E +
Sbjct: 1546 VALEEVEGSLEHEESKILRVQL-ELSQVKSELDRKVIEKDEEIEQLK-RNSQRAAEALQS 1603
Query: 447 LIEIQTVRGSNEEVTLNLK 465
+++ + +R N+ + L K
Sbjct: 1604 VLDAE-IRSRNDALRLKKK 1621
Score = 32.7 bits (71), Expect = 3.2
Identities = 29/203 (14%), Positives = 86/203 (42%), Gaps = 1/203 (0%)
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+++ ++E +E +E++ L+++ ND + EN+ + + K L ++
Sbjct: 865 EELARSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVK 924
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKE 434
+ +E E + + + + + + D+ +L ++ TE + L E
Sbjct: 925 ELTERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLELTLTKVEKEKHATENKVKNLSE 984
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
++ LE +L E ++++ ++++ +L+ + +D++ + +
Sbjct: 985 EMTALEENISKLTKEKKSLQEAHQQTLDDLQVEEDKVNGLIKINAKLEQQTDDLEGSLEQ 1044
Query: 495 WKSQFEDLDDVMKQQQKELKLGK 517
K DL+ ++ + +LK+ +
Sbjct: 1045 EKKLRADLERAKRKLEGDLKMSQ 1067
>AF083322-1|AAC32373.1| 994|Homo sapiens centriole associated
protein CEP110 protein.
Length = 994
Score = 59.3 bits (137), Expect = 3e-08
Identities = 104/504 (20%), Positives = 218/504 (43%), Gaps = 56/504 (11%)
Query: 23 KIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTE 82
KI+ EE KEI ++ + + K +L +E+ + + + L E
Sbjct: 181 KIKQEEILKEINKIVAAKDSDFQCLSKKKEKL-TEELQKLQKDIEMAERNEDHHLQVLKE 239
Query: 83 KLTIAETKHNDLKKLYEDSASELEALKRENIQM-HTSDVMVVPEIIDSLTEVINTLTNGF 141
+ + K +L+KL S+ + + + Q+ H + + + + S+ + L
Sbjct: 240 SEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ--GSMVQAKADLQ--- 294
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETDINELRNSIKYLESVKSEYNTA 200
E+L E+ K N I + +K+LL++L K E ++ ++ L +K E
Sbjct: 295 EALRLGETEVTEKCNHIRE----VKSLLEELSFQKGELNV-QISERKTQLTLIKQEIEKE 349
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L L + +Q +D+L++EN L D+ ++ L
Sbjct: 350 EENLQVVLRQMSKHKTELQNILDMLQLENHEL--------------QGLKLQHDQRVSEL 395
Query: 261 EEMKTMLVEEKLS--EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
E+ + ++EEKL +++ + K EI+ + L D+RE E M ++ L + +
Sbjct: 396 EKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREI-ERMTAESRALQSCVECL 454
Query: 319 NKTERELEEK----QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+K + +L+EK +++L L E NS K+ ++ K+ D + +L EL
Sbjct: 455 SKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS-KMEQSNLEKL-----DLNV-RKLQQEL 507
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
D + +++SL N I+ + Q+ E ++ N+ ++++A++ + + K+
Sbjct: 508 DQLNR---DKLSLH-----NDISAMQQQLQEKREAVNS-----LQEELANVQDHLNLAKQ 554
Query: 435 RLSQLETENKELLIEIQT-VRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
L T+++++L+ QT ++ E +D NEIE+ K K++
Sbjct: 555 DLLHT-TKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLV 613
Query: 494 EWKSQFEDLDDVMKQQQKELKLGK 517
+ + F+ L + ++ +L+ K
Sbjct: 614 QQEMMFQRLQKERESEESKLETSK 637
Score = 46.4 bits (105), Expect = 2e-04
Identities = 69/312 (22%), Positives = 135/312 (43%), Gaps = 24/312 (7%)
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKN-ETDINELRNSIKYLESVKSEYNTANEK 203
EE L++ L++ S K ++ +LD L +N E +L++ + E K++ EK
Sbjct: 349 EEENLQVVLRQMS--KHKTELQNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 406
Query: 204 L-FEQLNNAVDKQNC-IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
L E L +Q I+ + LL+ + + + + ++ +L+
Sbjct: 407 LELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKE----DLQ 462
Query: 262 EMKTMLVEEKLSEIKE----KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
E K + E+KL++ K +EN K E L EKL + R+ + + + N L
Sbjct: 463 E-KCDIWEKKLAQTKRVLAAAEENSKMEQSNL-EKLDLNVRKLQQELDQLNRDKLSLHND 520
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD-D 376
++ +++L+EK+E + L E+L + +++ +++ + D +S Q + D
Sbjct: 521 ISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKH--QDVLLSEQTRLQKDIS 578
Query: 377 ESENTYERISLTLDKITNHITYLNTQINET------QKNDNAQLLWEAKKQIADLTEQNI 430
E N +E + + L +I E Q+ +L E + + + L +
Sbjct: 579 EWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKV 638
Query: 431 ILKERLSQLETE 442
LKE+ QLE E
Sbjct: 639 TLKEQQHQLEKE 650
Score = 39.9 bits (89), Expect = 0.021
Identities = 79/448 (17%), Positives = 182/448 (40%), Gaps = 35/448 (7%)
Query: 35 QLKSGLQQNVGVGDKTVAELKND--EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHN 92
Q K+ LQ+ + +G+ V E N E+ S++ +L +LT+ +
Sbjct: 288 QAKADLQEALRLGETEVTEKCNHIREVKSLLEELSFQKGELNVQISERKTQLTLIK---Q 344
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMVVPEI--IDSLTEVINTLTNGFESLEEVALE 150
+++K E+ L + + ++ M+ E + L + + E + LE
Sbjct: 345 EIEKEEENLQVVLRQMSKHKTELQNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLE 404
Query: 151 IDLKKNSITKDNISIKTLLD---KLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
L+ ++ + + K ++ +L+ +++ +I + + L+S + E L E+
Sbjct: 405 EKLELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKEDLQEK 464
Query: 208 LN----NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
+ + + + K+E NL + + ++ M
Sbjct: 465 CDIWEKKLAQTKRVLAAAEENSKMEQSNLEKLDLNVRKLQQELDQLNRDKLSLHNDISAM 524
Query: 264 KTMLVE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ L E E ++ ++E+ N + +++ + L+ + + + E+ L D+S+ N+
Sbjct: 525 QQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRF 584
Query: 322 E---RELEEKQEQLTHLMEQLNDTENNSYKLI--ENMFNKVSQIASDFKISNQLSCELDD 376
E +E E KQ+QL L N+ E N KL+ E MF ++ + + + S
Sbjct: 585 EDCQKEEETKQQQLQVLQ---NEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLK 641
Query: 377 ESENTYERISLT-----LDKITNHITYLNTQINETQKNDN-----AQLLWEAKKQIADLT 426
E ++ E+ LT LD++ + + ++ Q+ + + L + K+Q+++
Sbjct: 642 EQQHQLEK-ELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSERE 700
Query: 427 EQNIILKERLSQLETENKELLIEIQTVR 454
+Q + L L+ E + + +R
Sbjct: 701 QQLVEKSGELLALQKEADSMRADFSLLR 728
Score = 38.7 bits (86), Expect = 0.049
Identities = 59/337 (17%), Positives = 131/337 (38%), Gaps = 18/337 (5%)
Query: 4 NEATLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMI 63
++ L + ++ I + R E+C KE + QQ + V + E K + +
Sbjct: 562 HQDVLLSEQTRLQKDISEWANRFEDCQKE----EETKQQQLQVLQNEIEENKLKLVQQEM 617
Query: 64 RQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENI--QMHTSDVM 121
T K+T+ E +H L+K D S+L+ + + + + +
Sbjct: 618 MFQRLQKERESEESKLETSKVTLKEQQHQ-LEKELTDQKSKLDQVLSKVLAAEERVRTLQ 676
Query: 122 VVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDIN 181
+SL + ++ E+ +E + ++ K+ S++ D + +N+ +
Sbjct: 677 EEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRA--DFSLLRNQF-LT 733
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
E + + K + S+K +L + L + +CIQ+E+ +++ Q+ +
Sbjct: 734 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMK 793
Query: 242 XXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFN 301
K +AN +++ E + EI + K E+ +++ + N
Sbjct: 794 ELNQMQYEYTELKKQMANQKDL-----ERRQMEISDAMRTLKSEV---KDEIRTSLKNLN 845
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ + E L + ++ E ELE +E L M +
Sbjct: 846 QFLPELPADLEAILERNENLEGELESLKENLPFTMNE 882
>AB201172-1|BAE44387.1| 1870|Homo sapiens girdin protein.
Length = 1870
Score = 59.3 bits (137), Expect = 3e-08
Identities = 93/449 (20%), Positives = 189/449 (42%), Gaps = 37/449 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMV--VPEIIDSLTEVINTLTN 139
E+L I+ + L+K + E L+++ Q+ + + EI D+ E N
Sbjct: 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Query: 140 GFESLEE-VALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYN 198
E + ++ EI + K S + L +L +N+ + IK L +++ +
Sbjct: 861 NLEKENKTLSKEIGIYKESCVR--------LKELEKENKELVKRATIDIKTLVTLREDL- 911
Query: 199 TANEKL-FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFI 257
+EKL +Q+NN ++K + E++ + + + LL + K
Sbjct: 912 -VSEKLKTQQMNNDLEK---LTHELEKIGLNKERLLHDEQSTDDRYKLLESKLESTLKKS 967
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL-ICDRREFNETMQEKNILLSDLSK 316
++E K +E +L E ++ +QE+ + + +R+ E M + + +S
Sbjct: 968 LEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS---PPISG 1024
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
+ NK ERE +E +L + ++L + E N+ L +Q+ +N L ++
Sbjct: 1025 EDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQILA 1084
Query: 377 ESENTY--ERISLTLDKITNHITYLNTQINETQK---NDNAQLLWEAKKQIADLTEQNII 431
T + + TL + N+ +N N NAQLL + Q + E +
Sbjct: 1085 LQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ---QSSLENENESV 1141
Query: 432 LKERLSQLETENKELL-----IEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIE 486
+KER L++ L+ +E+ R ++E +L K + ++E
Sbjct: 1142 IKER-EDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEH--RDLE 1198
Query: 487 DMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
D ++++ K Q EDL+ ++K +Q+++ L
Sbjct: 1199 DRYNQLLKQKGQLEDLEKMLKVEQEKMLL 1227
Score = 53.6 bits (123), Expect = 2e-06
Identities = 88/432 (20%), Positives = 192/432 (44%), Gaps = 48/432 (11%)
Query: 53 ELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIA----ETKHNDLKKLYEDSASELEAL 108
+L+N E+ S QL TE+L ++ + ++ L+K E+S +++ L
Sbjct: 724 QLENKELESEKEQLKKGLELLKASFKK-TERLEVSYQGLDIENQRLQKTLENSNKKIQQL 782
Query: 109 KRE--NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIK 166
+ E +++M + E + ++ + L +SLE+ +++ K + K+N K
Sbjct: 783 ESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN---K 839
Query: 167 TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLK 226
L + K +T + E N++K + +++ E T ++++ + K++C++ + L+
Sbjct: 840 RLRQQAEIK-DTTLEE--NNVK-IGNLEKENKTLSKEI------GIYKESCVR--LKELE 887
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEI 286
EN+ L++ R+ ++ E++KT + L ++ + E
Sbjct: 888 KENKELVKRATIDIKTLVTL------REDLVS--EKLKTQQMNNDLEKLTHELEKIGLNK 939
Query: 287 DML--NEKLICDRREFNETMQEKNIL--LSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
+ L +E+ DR + E+ E + L +K+ E LEE L ++L
Sbjct: 940 ERLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTV 999
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKIT----NHITY 398
+ N Y+ ++ ++ + S IS + + + + ES+ T + D++ N+ T
Sbjct: 1000 KKN-YEALKQRQDEERMVQSSPPISGEDN-KWERESQETTRELLKVKDRLIEVERNNATL 1057
Query: 399 ------LNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEI 450
L TQ+ ETQ N+ + ++Q L EQN L+ + ++L+ EN L +
Sbjct: 1058 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQS 1117
Query: 451 QTVRGSNEEVTL 462
++ N ++ +
Sbjct: 1118 TSLMNQNAQLLI 1129
Score = 52.8 bits (121), Expect = 3e-06
Identities = 108/501 (21%), Positives = 200/501 (39%), Gaps = 37/501 (7%)
Query: 24 IRLEECYKEIGQLKS----GLQQNVGVGDKTVAE-LKNDEINSMIRQLXXXXXXXXXXXX 78
+RL+E KE +L ++ V + + V+E LK ++N+ + +L
Sbjct: 881 VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKE 940
Query: 79 XLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L + ++ L+ E + + +K E I + + L + + T+
Sbjct: 941 RLLHDEQSTDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTVK 1000
Query: 139 NGFESLEEVALEIDLKKNSIT---KDNI----SIKTLLDKLITKNETDINELRNSIKYLE 191
+E+L++ E + ++S +DN S +T + L K+ + E+ + L+
Sbjct: 1001 KNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDR--LIEVERNNATLQ 1058
Query: 192 SVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXX 251
+ K T ++L Q NN + +Q + L+ +N L
Sbjct: 1059 AEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQST 1118
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDML---NEKL-ICDRREFNE--TMQ 305
+ A L ++ L E S IKE+ E+ K D L +EKL + R+ +E ++
Sbjct: 1119 SLMNQNAQLLIQQSSLENENESVIKER-EDLKSLYDSLIKDHEKLELLHERQASEYESLI 1177
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF--NKVSQ-IAS 362
K+ L K + R+LE++ QL QL D E E M NK + +A+
Sbjct: 1178 SKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVAA 1237
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKI-TNHITYL----NTQINETQKNDNAQLLWE 417
++K C +D +TY ++ + + T+H N+++ +T+ L E
Sbjct: 1238 EYK----KLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLKE 1293
Query: 418 AKKQI----ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
+Q+ L Q +L + LE EN+ LL +IQT+ N + +S
Sbjct: 1294 QYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFHV 1353
Query: 474 XXXXXXXXSNEIEDMKTKVME 494
NE+ K K+ E
Sbjct: 1354 EQRQYIDKLNELRRQKEKLEE 1374
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
E+ Q ++ L+D K+ + +ELEEK EQL ++L E +L + N +S
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 303
Query: 362 SDFKISNQLSC--ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
S ++L E + +S +++ + I + ++ E K DN Q+L E K
Sbjct: 304 SARMYRDELDALREKAVRVDKLESEVSRYKERL-HDIEFYKARVEEL-KEDN-QVLLETK 360
Query: 420 KQIADLTEQNIILKERLSQLETENKEL 446
+ D E ++L +LE EN +L
Sbjct: 361 TMLEDQLEGTRARSDKLHELEKENLQL 387
Score = 49.6 bits (113), Expect = 3e-05
Identities = 77/429 (17%), Positives = 182/429 (42%), Gaps = 26/429 (6%)
Query: 99 EDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
E +AS++ +++EN ++ ++ EI+ + N + ++E A L+K
Sbjct: 487 EGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA---QLEKTIE 543
Query: 159 TKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTA-----NEKLFEQLNNAVD 213
T S + + K++ + +N+ +S++ + +E N+ L E +
Sbjct: 544 TLRENSERQI--KILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSS 601
Query: 214 KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLS 273
K + I+ E +K E ++ + + + +K + EK+
Sbjct: 602 KLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLK--ITCEKIE 659
Query: 274 EIKEKDENFKQEIDMLNEKLICDRR-EFN-ETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
+++++ ++E L + L + F E+++++N L + + ++ + L+ +
Sbjct: 660 ALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMK 719
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD-ESENTYERISLTLD 390
+ L QL + E S K E + + + + FK + +L + EN +R+ TL+
Sbjct: 720 MAQL--QLENKELESEK--EQLKKGLELLKASFKKTERLEVSYQGLDIEN--QRLQKTLE 773
Query: 391 KITNHITYLNTQINETQKND-----NAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
I L +++ + + + N + L + K++ L ++N L++ SQLE + K+
Sbjct: 774 NSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Query: 446 LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDV 505
L E + +R E L++++ S EI K + K ++ ++
Sbjct: 834 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKEL 893
Query: 506 MKQQQKELK 514
+K+ ++K
Sbjct: 894 VKRATIDIK 902
Score = 35.1 bits (77), Expect = 0.60
Identities = 83/452 (18%), Positives = 176/452 (38%), Gaps = 30/452 (6%)
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
+ + + D++ L ++ A L+ L E + H+ ++ + E D L + + ++
Sbjct: 176 MEVTDMSQEDIEPLLKNMALHLKRLIDERDE-HSETIIELSEERDGLHFLPHASSSAQSP 234
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
++ + ++ + K + +L + E +L + + LE ++ E ++
Sbjct: 235 CGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE 294
Query: 204 LFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN-- 259
L++A + ++E+D L K + L+ AR + +
Sbjct: 295 NMNLLSDARSAR-MYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDN 353
Query: 260 --LEEMKTMLVEE---------KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
L E KTML ++ KL E+++++ K ++ + + DR++ E M+E N
Sbjct: 354 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE-N 412
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN 368
+ L K+ L + EQ++ E L++ S L + S ++ N
Sbjct: 413 MTLEMAQKQSMDESLHLGWELEQISRTSE-LSEAPQKS--LGHEVNELTSSRLLKLEMEN 469
Query: 369 QLSCELDDESENTYERISLTLDKI-----TNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
Q + +E T + + KI N +I E + Q L +
Sbjct: 470 QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 529
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL-NLKDSSTXXXXXXXXXXXXS 482
DL ++ L++ + L EN E I+I + T+ +L+ S
Sbjct: 530 DLMKEKAQLEKTIETLR-ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE 588
Query: 483 NEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
N+I + + E S+ ++ +Q +KEL+
Sbjct: 589 NKI--LHESIKETSSKLSKIEFEKRQIKKELE 618
>Z38133-1|CAA86293.1| 1937|Homo sapiens Myosin protein.
Length = 1937
Score = 58.8 bits (136), Expect = 4e-08
Identities = 79/422 (18%), Positives = 170/422 (40%), Gaps = 19/422 (4%)
Query: 43 NVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLK--KLYED 100
N+ KT E + D++ + Q L L +A+ D++ K D
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
Query: 101 SASELEALKRENIQMHTSDVMVVP----EIIDSLTEVINTLTNGFESLEEVALEIDLKKN 156
E + + N+ D V + I L I L E+ + + +++
Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
Query: 157 SITKDNISIKTLLDKL--ITKNETDINELRNS-IKYLESVKSEYNTANEKLFEQLNNA-V 212
++++ I L++ T + ++N+ R + + L E +E + L
Sbjct: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200
Query: 213 DKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKL 272
D + E++D L+ Q L + A K NLE+M L E+++
Sbjct: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSL-EDQV 1259
Query: 273 SEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
SE+K K+E ++ I+ L +L + E++ + EK+ L+S LS+ + +++EE
Sbjct: 1260 SELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEE-- 1317
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
L H +E+ +N +++ + + ++ + EL ++
Sbjct: 1318 --LKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWR 1375
Query: 390 DKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIE 449
K ++ E +K AQ L EA++ + + + L++ +L+ E ++L+++
Sbjct: 1376 TKYETDAIQRTEELEEAKKK-LAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 1434
Query: 450 IQ 451
++
Sbjct: 1435 VE 1436
Score = 44.4 bits (100), Expect = 0.001
Identities = 90/465 (19%), Positives = 196/465 (42%), Gaps = 34/465 (7%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q +++V + A L+ + + + + L L +K
Sbjct: 1389 LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKK 1448
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
+ ++ K+ YE++ +ELEA ++E+ + T ++ V + + + + TL ++
Sbjct: 1449 QRNFDKVLSEWKQKYEETQAELEASQKESRSLST-ELFKVKNVYEESLDQLETLRRENKN 1507
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLE-SVKSEYNTANE 202
L++ EI I + I L+K+ + E + E++ +++ E S++ E
Sbjct: 1508 LQQ---EISDLTEQIAEGGKQIHE-LEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILR 1563
Query: 203 KLFE--QLNNAVDKQNCIQ-EEVDLLKIENQNLLQX-XXXXXXXXXXXXXXXXARDKFIA 258
E Q+ + VD++ + EE+D LK + +++ + K
Sbjct: 1564 IQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEG 1623
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL--ICDRREFNETMQEK--------N 308
+L EM+ L E N++ +L E + D E ++E+ N
Sbjct: 1624 DLNEMEIQL-NHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRAN 1682
Query: 309 IL---LSDLSKKVNKTERELEEKQEQLTHLME--QLNDTENNS-YKLIENMFNKVSQIAS 362
+L + +L + +TER + +++L E QL T+N S + + N VSQ+ S
Sbjct: 1683 LLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQS 1742
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
+ + Q S +++++ ++ +++ +T + + N + + +
Sbjct: 1743 EVEEVIQESRNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNLEQTVKDLQHR 1799
Query: 423 ADLTEQNIIL--KERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
D EQ + K+++ +LE +EL E++ + N E L+
Sbjct: 1800 LDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLR 1844
Score = 43.6 bits (98), Expect = 0.002
Identities = 64/327 (19%), Positives = 142/327 (43%), Gaps = 39/327 (11%)
Query: 190 LESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXX 249
LE+ + E + + +LF+ + N ++ ++++ L+ EN+NL Q
Sbjct: 1470 LEASQKESRSLSTELFK-VKNVYEES---LDQLETLRRENKNLQQEISDLTEQIAEGG-- 1523
Query: 250 XXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNI 309
K I LE++K + +EK EI+ E + ++ K++ + E N+
Sbjct: 1524 -----KQIHELEKIKKQVEQEKC-EIQAALEEAEASLEHEEGKILRIQLELNQ------- 1570
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
+ S++ +K+ + + E+++ + T ++E + T + + + ++ D N+
Sbjct: 1571 VKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDL---NE 1627
Query: 370 LSCELDDESENTYERISLTLDKITNHITYLNTQ--INETQKNDNAQLLWEAKKQIADLTE 427
+ +L+ + L + + N Y NTQ + ETQ + L +A + DL E
Sbjct: 1628 MEIQLNHANR-------LAAESLRN---YRNTQGILKETQLH-----LDDALRGQEDLKE 1672
Query: 428 QNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED 487
Q I++ R + L+ E +EL ++ S + L D+S N +
Sbjct: 1673 QLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1732
Query: 488 MKTKVMEWKSQFEDLDDVMKQQQKELK 514
++ V + +S+ E++ + +++ K
Sbjct: 1733 LENDVSQLQSEVEEVIQESRNAEEKAK 1759
Score = 37.5 bits (83), Expect = 0.11
Identities = 37/221 (16%), Positives = 99/221 (44%), Gaps = 6/221 (2%)
Query: 302 ETMQEKNILLSDLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
ET +E + + K ++ K+E + +E +E++ L+++ ND + +++ +
Sbjct: 847 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEE 906
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWE 417
+ K QL ++ + +E E + + +T L + +E +K+ D+ +L
Sbjct: 907 RCEQLIKNKIQLEAKIKEVTERAEEEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLA 965
Query: 418 AKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXX 476
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 966 KVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTK 1025
Query: 477 XXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+++D++ + + K DL+ ++ + +LKL +
Sbjct: 1026 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1066
Score = 32.7 bits (71), Expect = 3.2
Identities = 52/265 (19%), Positives = 110/265 (41%), Gaps = 17/265 (6%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L E+L I E + N L+ E+ + LE +R ++ +++ E + L +L N
Sbjct: 1670 LKEQLAIVERRANLLQAEIEELWATLEQTERSR-KIAEQELLDASERVQLLHTQNTSLIN 1728
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR---NSIKYLESVKSE 196
+ LE ++ + + +++ + + K IT EL+ ++ +LE +K
Sbjct: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
+ L +L+ A +Q ++ ++ + + K
Sbjct: 1789 LEQTVKDLQHRLDEA--EQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKH 1846
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
++E+ E++ + ++ +D +D L K+ +R+ E ++ N LS
Sbjct: 1847 ERRVKELTYQTEEDRKNVLRLQDL-----VDKLQAKVKSYKRQAEEAEEQSNANLS---- 1897
Query: 317 KVNKTERELEEKQEQLTHLME-QLN 340
K K + ELEE +E+ H+ E Q+N
Sbjct: 1898 KFRKLQHELEEAEER-AHIAESQVN 1921
>BX537964-1|CAD97928.1| 898|Homo sapiens hypothetical protein
protein.
Length = 898
Score = 58.4 bits (135), Expect = 6e-08
Identities = 80/378 (21%), Positives = 156/378 (41%), Gaps = 31/378 (8%)
Query: 88 ETKHNDLKKLYEDSASELEAL---KRENIQMHTSDVMVVPEIIDSLTE---VINTLTNGF 141
E K N+L + ELE K + ++MH + + + ++ + E + TL
Sbjct: 446 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 505
Query: 142 ESLEEVAL----EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ LE+ L E+ K I + I+ LLDK+ T ++ +L+ + +E++K E
Sbjct: 506 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQ-EQLQRGKQEIENLKEEV 564
Query: 198 NTANEKLFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
+ N L L ++ + E+ L ++ ++N Q + +
Sbjct: 565 ESLNS-LINDLQKDIEGSRKRESELLLFTERLTSKNA-QLQSESNSLQSQFDKVSCSESQ 622
Query: 256 FIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
+ E+MK + + +KE +E K+E+ L +L C + E + L +L
Sbjct: 623 LQSQCEQMKQTNINLESRLLKE-EELRKEEVQTLQAELACRQTEVKALSTQVEELKDELV 681
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSY-KLIENMFNKVSQIASDFKISNQLSCEL 374
+ K +++ +QL +L+ E+ SY K + +M ++ S S N S
Sbjct: 682 TQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGS----LNARSSAE 737
Query: 375 DDESENTYERISL----TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE--- 427
D ENT +++ +DK + Q +KN+ + + + KQ+ +
Sbjct: 738 DRSPENTGSSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKT 797
Query: 428 ---QNIILKERLSQLETE 442
Q+ IL+E L +E
Sbjct: 798 KIIQSYILREESGTLSSE 815
Score = 39.9 bits (89), Expect = 0.021
Identities = 55/286 (19%), Positives = 125/286 (43%), Gaps = 25/286 (8%)
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL- 310
A+D N + + +++ + +K E +QE + + K + +E + +EK L
Sbjct: 274 AQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLE 333
Query: 311 --LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKI- 366
L D +K++ K ++++ ++ L + E + +LI + I S K+
Sbjct: 334 KKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVK 393
Query: 367 --SNQLSCELDDESENTYERISLTLDKIT----------NHITYLNTQINETQKNDNAQL 414
N+L E+D E T +++ T K+T + + E+++ + +L
Sbjct: 394 WAQNKLKAEMDSHKE-TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNEL 452
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXX 474
+ + +L +Q ++E+ QLE + ++ E++ ++ + +E L+ T
Sbjct: 453 DAKLRVTKGELEKQ---MQEKSDQLEMHHAKIK-ELEDLKRTFKEGMDELRTLRTKVKCL 508
Query: 475 XXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMK---QQQKELKLGK 517
+E+ K + K++ ++L D +K Q Q++L+ GK
Sbjct: 509 EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGK 554
Score = 35.1 bits (77), Expect = 0.60
Identities = 47/259 (18%), Positives = 105/259 (40%), Gaps = 17/259 (6%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+ +EE+ V+ ++ +D K + L++++ + N+ +E + K
Sbjct: 256 SRIEELNKE-VKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMK 314
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE 377
+ E+E + +++ L ++L D K +E NK+ Q++ + +QL + E
Sbjct: 315 YVRGEKESLDLRKEKETLEKKLRDAN----KELEKNTNKIKQLSQEKGRLHQLYETKEGE 370
Query: 378 SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS 437
+ I + I +H+ + N+ + ++ E K ++ + T + KE
Sbjct: 371 TTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHK--ETKDKLKETTTKLTQAKEEAD 428
Query: 438 QLETENKELLIEIQTVRGSNEEVTLNLKDSS--TXXXXXXXXXXXXSNEIEDMKTKVMEW 495
Q+ ++++ Q +EE+ N D+ S+++E K+ E
Sbjct: 429 QIRKNCQDMIKTYQ----ESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKE- 483
Query: 496 KSQFEDLDDVMKQQQKELK 514
EDL K+ EL+
Sbjct: 484 ---LEDLKRTFKEGMDELR 499
Score = 31.9 bits (69), Expect = 5.6
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 12/203 (5%)
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDM-LNEKLICDRREFNETMQEKNILLSDLSKKV 318
LEE+++ L+ + +E + + K E + L EK + D+ E + +K L+ + +KK
Sbjct: 163 LEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCVQDKYLQQEHIIKK--LIKE-NKKH 219
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ ++ +++ L +++ +TE I+ + +++ ++ + K S D +
Sbjct: 220 QELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTA 279
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL--WEAKKQIADLTEQNIILKERL 436
+N +++ ++ + N + E ++ A ++ +K+ DL ++ L+++
Sbjct: 280 KNAVQQLH---KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKK- 335
Query: 437 SQLETENKELLIEIQTVRGSNEE 459
L NKEL ++ ++E
Sbjct: 336 --LRDANKELEKNTNKIKQLSQE 356
>BC105632-1|AAI05633.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 58.4 bits (135), Expect = 6e-08
Identities = 80/378 (21%), Positives = 156/378 (41%), Gaps = 31/378 (8%)
Query: 88 ETKHNDLKKLYEDSASELEAL---KRENIQMHTSDVMVVPEIIDSLTE---VINTLTNGF 141
E K N+L + ELE K + ++MH + + + ++ + E + TL
Sbjct: 446 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 505
Query: 142 ESLEEVAL----EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ LE+ L E+ K I + I+ LLDK+ T ++ +L+ + +E++K E
Sbjct: 506 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQ-EQLQRGKQEIENLKEEV 564
Query: 198 NTANEKLFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
+ N L L ++ + E+ L ++ ++N Q + +
Sbjct: 565 ESLNS-LINDLQKDIEGSRKRESELLLFTERLTSKNA-QLQSESNSLQSQFDKVSCSESQ 622
Query: 256 FIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
+ E+MK + + +KE +E K+E+ L +L C + E + L +L
Sbjct: 623 LQSQCEQMKQTNINLESRLLKE-EELRKEEVQTLQAELACRQTEVKALSTQVEELKDELV 681
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSY-KLIENMFNKVSQIASDFKISNQLSCEL 374
+ K +++ +QL +L+ E+ SY K + +M ++ S S N S
Sbjct: 682 TQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGS----LNARSSAE 737
Query: 375 DDESENTYERISL----TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE--- 427
D ENT +++ +DK + Q +KN+ + + + KQ+ +
Sbjct: 738 DRSPENTGSSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKT 797
Query: 428 ---QNIILKERLSQLETE 442
Q+ IL+E L +E
Sbjct: 798 KIIQSYILREESGTLSSE 815
Score = 39.9 bits (89), Expect = 0.021
Identities = 55/286 (19%), Positives = 125/286 (43%), Gaps = 25/286 (8%)
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL- 310
A+D N + + +++ + +K E +QE + + K + +E + +EK L
Sbjct: 274 AQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLE 333
Query: 311 --LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKI- 366
L D +K++ K ++++ ++ L + E + +LI + I S K+
Sbjct: 334 KKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVK 393
Query: 367 --SNQLSCELDDESENTYERISLTLDKIT----------NHITYLNTQINETQKNDNAQL 414
N+L E+D E T +++ T K+T + + E+++ + +L
Sbjct: 394 WAQNKLKAEMDSHKE-TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNEL 452
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXX 474
+ + +L +Q ++E+ QLE + ++ E++ ++ + +E L+ T
Sbjct: 453 DAKLRVTKGELEKQ---MQEKSDQLEMHHAKIK-ELEDLKRTFKEGMDELRTLRTKVKCL 508
Query: 475 XXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMK---QQQKELKLGK 517
+E+ K + K++ ++L D +K Q Q++L+ GK
Sbjct: 509 EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGK 554
Score = 35.1 bits (77), Expect = 0.60
Identities = 47/259 (18%), Positives = 105/259 (40%), Gaps = 17/259 (6%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+ +EE+ V+ ++ +D K + L++++ + N+ +E + K
Sbjct: 256 SRIEELNKE-VKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMK 314
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE 377
+ E+E + +++ L ++L D K +E NK+ Q++ + +QL + E
Sbjct: 315 YVRGEKESLDLRKEKETLEKKLRDAN----KELEKNTNKIKQLSQEKGRLHQLYETKEGE 370
Query: 378 SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS 437
+ I + I +H+ + N+ + ++ E K ++ + T + KE
Sbjct: 371 TTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHK--ETKDKLKETTTKLTQAKEEAD 428
Query: 438 QLETENKELLIEIQTVRGSNEEVTLNLKDSS--TXXXXXXXXXXXXSNEIEDMKTKVMEW 495
Q+ ++++ Q +EE+ N D+ S+++E K+ E
Sbjct: 429 QIRKNCQDMIKTYQ----ESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKE- 483
Query: 496 KSQFEDLDDVMKQQQKELK 514
EDL K+ EL+
Sbjct: 484 ---LEDLKRTFKEGMDELR 499
Score = 31.9 bits (69), Expect = 5.6
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 12/203 (5%)
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDM-LNEKLICDRREFNETMQEKNILLSDLSKKV 318
LEE+++ L+ + +E + + K E + L EK + D+ E + +K L+ + +KK
Sbjct: 163 LEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCVQDKYLQQEHIIKK--LIKE-NKKH 219
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ ++ +++ L +++ +TE I+ + +++ ++ + K S D +
Sbjct: 220 QELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTA 279
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL--WEAKKQIADLTEQNIILKERL 436
+N +++ ++ + N + E ++ A ++ +K+ DL ++ L+++
Sbjct: 280 KNAVQQLH---KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKK- 335
Query: 437 SQLETENKELLIEIQTVRGSNEE 459
L NKEL ++ ++E
Sbjct: 336 --LRDANKELEKNTNKIKQLSQE 356
>BC103499-1|AAI03500.1| 898|Homo sapiens chromosome 10 open reading
frame 118 protein.
Length = 898
Score = 58.4 bits (135), Expect = 6e-08
Identities = 80/378 (21%), Positives = 156/378 (41%), Gaps = 31/378 (8%)
Query: 88 ETKHNDLKKLYEDSASELEAL---KRENIQMHTSDVMVVPEIIDSLTE---VINTLTNGF 141
E K N+L + ELE K + ++MH + + + ++ + E + TL
Sbjct: 446 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 505
Query: 142 ESLEEVAL----EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ LE+ L E+ K I + I+ LLDK+ T ++ +L+ + +E++K E
Sbjct: 506 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQ-EQLQRGKQEIENLKEEV 564
Query: 198 NTANEKLFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
+ N L L ++ + E+ L ++ ++N Q + +
Sbjct: 565 ESLNS-LINDLQKDIEGSRKRESELLLFTERLTSKNA-QLQSESNSLQSQFDKVSCSESQ 622
Query: 256 FIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
+ E+MK + + +KE +E K+E+ L +L C + E + L +L
Sbjct: 623 LQSQCEQMKQTNINLESRLLKE-EELRKEEVQTLQAELACRQTEVKALSTQVEELKDELV 681
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSY-KLIENMFNKVSQIASDFKISNQLSCEL 374
+ K +++ +QL +L+ E+ SY K + +M ++ S S N S
Sbjct: 682 TQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGS----LNARSSAE 737
Query: 375 DDESENTYERISL----TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE--- 427
D ENT +++ +DK + Q +KN+ + + + KQ+ +
Sbjct: 738 DRSPENTGSSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKT 797
Query: 428 ---QNIILKERLSQLETE 442
Q+ IL+E L +E
Sbjct: 798 KIIQSYILREESGTLSSE 815
Score = 41.1 bits (92), Expect = 0.009
Identities = 66/346 (19%), Positives = 146/346 (42%), Gaps = 33/346 (9%)
Query: 198 NTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFI 257
N +++LF + + +K N +E + E Q++ +RDK I
Sbjct: 216 NKKHQELFVDICS--EKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDKLI 273
Query: 258 ANLEEMKTMLVE------EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL- 310
A K + + +++ + +K E +QE + + K + +E + +EK L
Sbjct: 274 AQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLE 333
Query: 311 --LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKI- 366
L D +K++ K ++++ ++ L + E + +LI + I S K+
Sbjct: 334 KKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVK 393
Query: 367 --SNQLSCELDDESENTYERISLTLDKIT----------NHITYLNTQINETQKNDNAQL 414
N+L E+D E T +++ T K+T + + E+++ + +L
Sbjct: 394 WAQNKLKAEMDSHKE-TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNEL 452
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXX 474
+ + +L +Q ++E+ QLE + ++ E++ ++ + +E L+ T
Sbjct: 453 DAKLRVTKGELEKQ---MQEKSDQLEMHHAKIK-ELEDLKRTFKEGMDELRTLRTKVKCL 508
Query: 475 XXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMK---QQQKELKLGK 517
+E+ K + K++ ++L D +K Q Q++L+ GK
Sbjct: 509 EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGK 554
Score = 31.9 bits (69), Expect = 5.6
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 12/203 (5%)
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDM-LNEKLICDRREFNETMQEKNILLSDLSKKV 318
LEE+++ L+ + +E + + K E + L EK + D+ E + +K L+ + +KK
Sbjct: 163 LEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCVQDKYLQQEHIIKK--LIKE-NKKH 219
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ ++ +++ L +++ +TE I+ + +++ ++ + K S D +
Sbjct: 220 QELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDKLIAQDVTA 279
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL--WEAKKQIADLTEQNIILKERL 436
+N +++ ++ + N + E ++ A ++ +K+ DL ++ L+++
Sbjct: 280 KNAVQQLH---KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKK- 335
Query: 437 SQLETENKELLIEIQTVRGSNEE 459
L NKEL ++ ++E
Sbjct: 336 --LRDANKELEKNTNKIKQLSQE 356
>BC100670-1|AAI00671.1| 1004|Homo sapiens C10orf118 protein protein.
Length = 1004
Score = 58.4 bits (135), Expect = 6e-08
Identities = 80/378 (21%), Positives = 156/378 (41%), Gaps = 31/378 (8%)
Query: 88 ETKHNDLKKLYEDSASELEAL---KRENIQMHTSDVMVVPEIIDSLTE---VINTLTNGF 141
E K N+L + ELE K + ++MH + + + ++ + E + TL
Sbjct: 552 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 611
Query: 142 ESLEEVAL----EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ LE+ L E+ K I + I+ LLDK+ T ++ +L+ + +E++K E
Sbjct: 612 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQ-EQLQRGKQEIENLKEEV 670
Query: 198 NTANEKLFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
+ N L L ++ + E+ L ++ ++N Q + +
Sbjct: 671 ESLNS-LINDLQKDIEGSRKRESELLLFTERLTSKNA-QLQSESNSLQSQFDKVSCSESQ 728
Query: 256 FIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
+ E+MK + + +KE +E K+E+ L +L C + E + L +L
Sbjct: 729 LQSQCEQMKQTNINLESRLLKE-EELRKEEVQTLQAELACRQTEVKALSTQVEELKDELV 787
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSY-KLIENMFNKVSQIASDFKISNQLSCEL 374
+ K +++ +QL +L+ E+ SY K + +M ++ S S N S
Sbjct: 788 TQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGS----LNARSSAE 843
Query: 375 DDESENTYERISL----TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE--- 427
D ENT +++ +DK + Q +KN+ + + + KQ+ +
Sbjct: 844 DRSPENTGSSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVEEIRKKT 903
Query: 428 ---QNIILKERLSQLETE 442
Q+ IL+E L +E
Sbjct: 904 KIIQSYILREESGTLSSE 921
Score = 39.9 bits (89), Expect = 0.021
Identities = 55/286 (19%), Positives = 125/286 (43%), Gaps = 25/286 (8%)
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL- 310
A+D N + + +++ + +K E +QE + + K + +E + +EK L
Sbjct: 380 AQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLE 439
Query: 311 --LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKI- 366
L D +K++ K ++++ ++ L + E + +LI + I S K+
Sbjct: 440 KKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVK 499
Query: 367 --SNQLSCELDDESENTYERISLTLDKIT----------NHITYLNTQINETQKNDNAQL 414
N+L E+D E T +++ T K+T + + E+++ + +L
Sbjct: 500 WAQNKLKAEMDSHKE-TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNEL 558
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXX 474
+ + +L +Q ++E+ QLE + ++ E++ ++ + +E L+ T
Sbjct: 559 DAKLRVTKGELEKQ---MQEKSDQLEMHHAKIK-ELEDLKRTFKEGMDELRTLRTKVKCL 614
Query: 475 XXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMK---QQQKELKLGK 517
+E+ K + K++ ++L D +K Q Q++L+ GK
Sbjct: 615 EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGK 660
Score = 35.1 bits (77), Expect = 0.60
Identities = 47/259 (18%), Positives = 105/259 (40%), Gaps = 17/259 (6%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+ +EE+ V+ ++ +D K + L++++ + N+ +E + K
Sbjct: 362 SRIEELNKE-VKASRDQLIAQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMK 420
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE 377
+ E+E + +++ L ++L D K +E NK+ Q++ + +QL + E
Sbjct: 421 YVRGEKESLDLRKEKETLEKKLRDAN----KELEKNTNKIKQLSQEKGRLHQLYETKEGE 476
Query: 378 SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS 437
+ I + I +H+ + N+ + ++ E K ++ + T + KE
Sbjct: 477 TTRLIREIDKLKEDINSHVIKVKWAQNKLKAEMDSHK--ETKDKLKETTTKLTQAKEEAD 534
Query: 438 QLETENKELLIEIQTVRGSNEEVTLNLKDSS--TXXXXXXXXXXXXSNEIEDMKTKVMEW 495
Q+ ++++ Q +EE+ N D+ S+++E K+ E
Sbjct: 535 QIRKNCQDMIKTYQ----ESEEIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKE- 589
Query: 496 KSQFEDLDDVMKQQQKELK 514
EDL K+ EL+
Sbjct: 590 ---LEDLKRTFKEGMDELR 605
Score = 31.9 bits (69), Expect = 5.6
Identities = 37/203 (18%), Positives = 95/203 (46%), Gaps = 12/203 (5%)
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDM-LNEKLICDRREFNETMQEKNILLSDLSKKV 318
LEE+++ L+ + +E + + K E + L EK + D+ E + +K L+ + +KK
Sbjct: 269 LEEIESELLSTEFAEHRVPNGMNKGEHALVLFEKCVQDKYLQQEHIIKK--LIKE-NKKH 325
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ ++ +++ L +++ +TE I+ + +++ ++ + K S D +
Sbjct: 326 QELFVDICSEKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDQLIAQDVTA 385
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL--WEAKKQIADLTEQNIILKERL 436
+N +++ ++ + N + E ++ A ++ +K+ DL ++ L+++
Sbjct: 386 KNAVQQLH---KEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLEKK- 441
Query: 437 SQLETENKELLIEIQTVRGSNEE 459
L NKEL ++ ++E
Sbjct: 442 --LRDANKELEKNTNKIKQLSQE 462
>U93121-1|AAB88727.1| 753|Homo sapiens M-phase phosphoprotein-1
protein.
Length = 753
Score = 58.0 bits (134), Expect = 7e-08
Identities = 75/369 (20%), Positives = 158/369 (42%), Gaps = 35/369 (9%)
Query: 171 KLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVD-----KQNCIQEEVDLL 225
K +K I EL I+ L++ Y N +L E+ + D K+ IQ+ + L
Sbjct: 2 KASSKKSHQIEELEQQIEKLQAEVKGYKDENNRLKEKEHKNQDDLLKEKETLIQQLKEEL 61
Query: 226 KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQE 285
+ +N L + A ++E++T+L +K+ E+ + K E
Sbjct: 62 QEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKELETILETQKV----ERSHSAKLE 117
Query: 286 IDMLNE-----KLICDRREFNETMQEKNILLSDLSKKVNKTERELEE---KQEQLTHLME 337
D+L + KL + +EF E +Q+ DL+ K K + E+ + + + HL++
Sbjct: 118 QDILEKESIILKLERNLKEFQEHLQDSVKNTKDLNVKELKLKEEITQLTNNLQDMKHLLQ 177
Query: 338 QLNDTENNSYKLIENMFNKVS-------QIASDFKISNQLSCELDDESENTYERISLTLD 390
+ E + + E + ++S + +D + + +L ++ + ++I
Sbjct: 178 LKEEEEETNRQETEKLKEELSASSARTQNLKADLQRKEEDYADLKEKLTDAKKQIKQVQK 237
Query: 391 KIT---NHITYLNTQINETQKNDN--AQLLWEAKKQIADLTEQ--NIILKERLSQLETEN 443
+++ + L +INE +K N +Q L ++ I L EQ N ++E + Q E
Sbjct: 238 EVSVMRDEDKLLRIKINELEKKKNQCSQELDMKQRTIQQLKEQLNNQKVEEAIQQYERAC 297
Query: 444 KELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLD 503
K+L ++ + + E++ + L++ E+E + T++ +WK + DL+
Sbjct: 298 KDLNVKEKII----EDMRMTLEEQEQTQVEQDQVLEAKLEEVERLATELEKWKEKCNDLE 353
Query: 504 DVMKQQQKE 512
Q+ +
Sbjct: 354 TKNNQRSNK 362
Score = 52.4 bits (120), Expect = 4e-06
Identities = 85/437 (19%), Positives = 187/437 (42%), Gaps = 41/437 (9%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMH-TSDVMV--VPEIIDSLTEVINTLT 138
E + E +H + L ++ + ++ LK E + + T DV + V E +L+E+ +T
Sbjct: 31 ENNRLKEKEHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVT 90
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDK--LITKNETDINELRNSIKYLESVKS- 195
++E+ ++ +K + + +L+K +I K E ++ E + ++ +SVK+
Sbjct: 91 CYKAKIKELETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQ--DSVKNT 148
Query: 196 -EYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ N KL E++ N +Q+ LL+++ +
Sbjct: 149 KDLNVKELKLKEEITQLT---NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQ 205
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
A+L+ EE +++KEK + K++I + +K + R+ ++ ++ K +++L
Sbjct: 206 NLKADLQRK-----EEDYADLKEKLTDAKKQIKQV-QKEVSVMRDEDKLLRIK---INEL 256
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
KK N+ +EL+ KQ + L EQLN+ + +E + + D + ++ ++
Sbjct: 257 EKKKNQCSQELDMKQRTIQQLKEQLNNQK------VEEAIQQYERACKDLNVKEKIIEDM 310
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
E E+ + D++ L ++ E ++ W K++ DL +N +
Sbjct: 311 RMTLEE-QEQTQVEQDQV------LEAKLEEVERLATELEKW--KEKCNDLETKN---NQ 358
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
R ++ N ++L ++ ++ +E + E E+++ K E
Sbjct: 359 RSNKEHENNTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNK--E 416
Query: 495 WKSQFEDLDDVMKQQQK 511
K ED + KQQ +
Sbjct: 417 MKKYAEDRERFFKQQNE 433
Score = 32.3 bits (70), Expect = 4.2
Identities = 65/350 (18%), Positives = 146/350 (41%), Gaps = 22/350 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTEKLTIA 87
+EI QL + LQ K + +LK +E + ++ L L L
Sbjct: 160 EEITQLTNNLQDM-----KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 214
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E + DLK+ D+ +++ +++E M D ++ +I + L + N + + +
Sbjct: 215 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI-NELEKKKNQCSQELDMKQRT 273
Query: 148 ALEI-DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE 206
++ + N ++ I K + E I ++R +++ E + E + E E
Sbjct: 274 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 333
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM--- 263
++ + +E+ + +E +N + +D+ + ++
Sbjct: 334 EVERLATELEKWKEKCN--DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNAD 391
Query: 264 KTMLVEEKLSEIKE--KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ +EEK+ I + + EN + + +M +K DR F + E IL + L++K +
Sbjct: 392 RKKWLEEKMMLITQAKEAENIRNK-EM--KKYAEDRERFFKQQNEMEILTAQLTEKDSDL 448
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQL 370
++ EE+ + + L QL +++ + +N ++ +I S+ KI Q+
Sbjct: 449 QKWREERDQLVAALEIQLKALISSNVQK-DNEIEQLKRIISETSKIETQI 497
>AK023707-1|BAB14650.1| 435|Homo sapiens protein ( Homo sapiens
cDNA FLJ13645 fis, clone PLACE1011310, weakly similar to
MYOSIN HEAVY CHAIN, GIZZARD SMOOTH MUSCLE. ).
Length = 435
Score = 58.0 bits (134), Expect = 7e-08
Identities = 88/376 (23%), Positives = 163/376 (43%), Gaps = 48/376 (12%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
+SL+ + E K+ I I+ +K T + L N +KYLE T N
Sbjct: 20 QSLDVIFTERQAKEKQIRSVEEEIEQ--EKQATDDIIKNMSLENQVKYLEM-----KTTN 72
Query: 202 EKLFEQLNNA---VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
EKL ++L+ +D QN +E ++ +I + + Q RD+ IA
Sbjct: 73 EKLLQELDTLQQQLDSQNMKKESLEA-EIAHSQVKQEAVLLHEKLYELESH---RDQMIA 128
Query: 259 NLEEMKTMLVEEKLSEIKE-KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK- 316
+ + + + EE+ +K+ KD+N QEI + +L + + N+ ++E L DL +
Sbjct: 129 EDKSIGSPM-EEREKLLKQIKDDN--QEIASMERQLTDTKEKINQFIEEIRQLDMDLEEH 185
Query: 317 --KVNKTERELEEKQEQLTHLMEQLNDTENNSYK-----------LIENMFNKVSQIASD 363
++N+ +EL++++E + +E +T+N K L+E+ +++I
Sbjct: 186 QGEMNQKYKELKKREEHMDTFIETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQI 245
Query: 364 FKISNQ-LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
I+NQ L DD + + E + K + L + I Q + L E+K
Sbjct: 246 SSITNQELKMMQDDLNFKSTE-----VQKSQSTAQNLTSDIQRLQLDLQKMELLESK--- 297
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS----STXXXXXXXXX 478
+TE+ LK ++ Q+ T+ E+ ++ ++ S EE L ST
Sbjct: 298 --MTEEQHSLKSKIKQMTTD-LEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIM 354
Query: 479 XXXSNEIEDMKTKVME 494
+ E E +KT++ E
Sbjct: 355 EKQNIEYEALKTQLQE 370
>BC114213-1|AAI14214.1| 1392|Homo sapiens CAP-GLY domain containing
linker protein 1 protein.
Length = 1392
Score = 57.6 bits (133), Expect = 1e-07
Identities = 100/472 (21%), Positives = 182/472 (38%), Gaps = 29/472 (6%)
Query: 10 ANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXX 69
A E + I A E+ KE LKS L+ +A K+ ++
Sbjct: 533 AREETHQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAM 592
Query: 70 XXXXXXXXXXL-TEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIID 128
L E AE K ++K+ D E+E L+ + + + +
Sbjct: 593 EELKVSFSKGLGAETAEFAELK-TQIEKMRLDYQHEIENLQNQQNSERAAHAKEMEALRA 651
Query: 129 SLTEVINTLTNGFESLEEVALEIDLKKNS-ITKDNISIKTLLDKLITKNETDINELR--N 185
L +VI N SLE + ++D ++ + + ++ L + I E ++ + +
Sbjct: 652 KLMKVIKEKEN---SLEAIRSKLDKAEDQHLVEMEDTLNKLQEAEIKVKELEVLQAKCNE 708
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
K +++ S+ EKL + +A+ K + E +K Q L
Sbjct: 709 QTKVIDNFTSQPKATEEKLLDL--DALRKAS--SEGKSEMKKLRQQLEAAEKQIKHLEIE 764
Query: 246 XXXXXXARDKFIANLE--EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRRE---F 300
L+ E+K ++E LSE+ + E ++E+ +L EK E
Sbjct: 765 KNAESSKASSITRELQGRELKLTNLQENLSEVSQVKETLEKELQILKEKFAEASEEAVSV 824
Query: 301 NETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
+MQE L ++ N +LE+ +E L + + + + +LI+ + I
Sbjct: 825 QRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDI 884
Query: 361 ASDFKISNQLSCEL---DDE---SENTYERISLTLDKITNHITYLNTQINE-TQKNDNAQ 413
A K+S S +L +DE E E + L L K + ++L I + T K + +Q
Sbjct: 885 AEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQ 944
Query: 414 LLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
EA K+ E+ L+ +LS LE + + + Q ++ E T K
Sbjct: 945 --QEAAKK---HEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSETK 991
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/434 (18%), Positives = 181/434 (41%), Gaps = 23/434 (5%)
Query: 82 EKLTIAETK-HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNG 140
E+L A+ K ND+ ++ + S L + N ++ + V E+ LT+ +
Sbjct: 871 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE-RDVEELQLKLTKANENASFL 929
Query: 141 FESLEEVALEIDLKKNSITKDNISIKTLLDKLIT----KNETDINELRNSIKYLESVKSE 196
+S+E++ ++ + + K + K L++ ++ K ET N+ + E SE
Sbjct: 930 QKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSE 989
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
T +E++ + L + ++++ + EN LLQ A D
Sbjct: 990 TKTKHEEILQNLQKTLLDT---EDKLKGAREENSGLLQELEELRKQADKAKAAQTAEDA- 1045
Query: 257 IANLEEMKTMLVEE--KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
+ +E+M E L + K+ + + E+D L E + + E N++ + LL+
Sbjct: 1046 MQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKE----LLTVE 1101
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++K+ + +E+E ++ +QL+ + + KL E + ++ S K+ + S L
Sbjct: 1102 NQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSV-L 1160
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNIIL 432
+++ +R S + L I+ T + L + + ++ L +N
Sbjct: 1161 NNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA 1220
Query: 433 KER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSS-TXXXXXXXXXXXXSNEIEDM 488
K + LE++ +L ++++ + +E L SS ++I+ +
Sbjct: 1221 KSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFL 1280
Query: 489 KTKVMEWKSQFEDL 502
+ +++ + + +DL
Sbjct: 1281 NSVIVDLQRKNQDL 1294
Score = 44.8 bits (101), Expect = 7e-04
Identities = 86/446 (19%), Positives = 178/446 (39%), Gaps = 30/446 (6%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L + + K N+ K+ ++ S+ +A + + + D+ + + + L
Sbjct: 697 KELEVLQAKCNEQTKVIDNFTSQPKATEEKLL-----DLDALRKASSEGKSEMKKLRQQL 751
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL-ESVKSEYNTA 200
E+ E+ ++++KN+ + SI L K T++ E + + + E+++ E
Sbjct: 752 EAAEKQIKHLEIEKNAESSKASSITRELQGRELKL-TNLQENLSEVSQVKETLEKELQIL 810
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
EK E AV Q +QE V+ L +Q Q KF
Sbjct: 811 KEKFAEASEEAVSVQRSMQETVNKL---HQKEEQFNMLSSDLEKLRENLADMEAKFREKD 867
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E EE+L + KEK EN EI ++ + N+ ++ K + +L K+ K
Sbjct: 868 ER------EEQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKERDVEELQLKLTK 921
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
Q+ + + + ++ + K E ++ + SD + + S E +
Sbjct: 922 ANENASFLQKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKA 981
Query: 381 TYER-ISLTLDKITNHITYLNTQINETQ------KNDNAQLLWEAK--KQIADLTEQNII 431
YER S T K + L + +T+ + +N+ LL E + ++ AD +
Sbjct: 982 RYERATSETKTKHEEILQNLQKTLLDTEDKLKGAREENSGLLQELEELRKQADKAKAAQT 1041
Query: 432 LKER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDM 488
++ + Q+ E E L ++ + +N ++ N D+ S E+ +
Sbjct: 1042 AEDAMQIMEQMTKEKTETLASLEDTKQTNAKLQ-NELDTLKENNLKNVEELNKSKELLTV 1100
Query: 489 KT-KVMEWKSQFEDLDDVMKQQQKEL 513
+ K+ E++ + E L Q+ ++L
Sbjct: 1101 ENQKMEEFRKEIETLKQAAAQKSQQL 1126
Score = 37.9 bits (84), Expect = 0.085
Identities = 84/425 (19%), Positives = 175/425 (41%), Gaps = 47/425 (11%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETK 90
+E+ +L+ L+ N GD ++ EI+S+ +L L E E
Sbjct: 478 QEVAELRRRLESNKPAGDVDMSLSLLQEISSLQEKLEVTRTDHQREITSLKEHFGAREET 537
Query: 91 HN-DLKKLY---EDSASELEALKR--ENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
H ++K LY E + E E+LK E+ SDV+ + + +++ + + +++
Sbjct: 538 HQKEIKALYTATEKLSKENESLKSKLEHANKENSDVIALWK-----SKLETAIASHQQAM 592
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKL 204
EE+ + + T + +KT ++K+ + +I L+N ++ A+ K
Sbjct: 593 EELKVSFSKGLGAETAEFAELKTQIEKMRLDYQHEIENLQNQ-------QNSERAAHAKE 645
Query: 205 FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMK 264
E L + K ++K E +N L+ A D+ + +E+
Sbjct: 646 MEALRAKLMK---------VIK-EKENSLEAIRSKLDK---------AEDQHLVEMEDTL 686
Query: 265 TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L E +EIK K+ Q K+I + + +EK + L L K ++ + E
Sbjct: 687 NKLQE---AEIKVKELEVLQAKCNEQTKVIDNFTSQPKATEEKLLDLDALRKASSEGKSE 743
Query: 325 LEEKQEQLTHLMEQLN--DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
+++ ++QL +Q+ + E N+ + + Q + K++N L L + S+
Sbjct: 744 MKKLRQQLEAAEKQIKHLEIEKNAESSKASSITRELQ-GRELKLTN-LQENLSEVSQ-VK 800
Query: 383 ERISLTLDKITNHITYLNTQINETQKN--DNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
E + L + + + Q++ + L + ++Q L+ L+E L+ +E
Sbjct: 801 ETLEKELQILKEKFAEASEEAVSVQRSMQETVNKLHQKEEQFNMLSSDLEKLRENLADME 860
Query: 441 TENKE 445
+ +E
Sbjct: 861 AKFRE 865
>AF273054-1|AAM44457.1| 613|Homo sapiens CTCL tumor antigen
HD-CL-01 protein.
Length = 613
Score = 57.6 bits (133), Expect = 1e-07
Identities = 74/354 (20%), Positives = 147/354 (41%), Gaps = 25/354 (7%)
Query: 88 ETKHNDLKKLYEDSASELEAL---KRENIQMHTSDVMVVPEIIDSLTE---VINTLTNGF 141
E K N+L + ELE K + ++MH + + + ++ + E + TL
Sbjct: 263 EIKSNELDAKLRVTKGELEKQMQEKSDQLEMHHAKIKELEDLKRTFKEGMDELRTLRTKV 322
Query: 142 ESLEEVAL----EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEY 197
+ LE+ L E+ K I + I+ LLDK+ T ++ +L+ + +E++K E
Sbjct: 323 KCLEDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQ-EQLQRGKQEIENLKEEV 381
Query: 198 NTANEKLFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
+ N L L ++ + E+ L ++ ++N Q + +
Sbjct: 382 ESLNS-LINDLQKDIEGSRKRESELLLFTERLTSKNA-QLQSESNSLQSQFDKVSCSESQ 439
Query: 256 FIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
+ E+MK + + +KE +E K+E+ L +L C + E + L +L
Sbjct: 440 LQSQCEQMKQTNINLESRLLKE-EELRKEEVQTLQAELACRQTEVKALSTQVEELKDELV 498
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSY-KLIENMFNKVSQIASDFKISNQLSCEL 374
+ K +++ +QL +L+ E+ SY K + +M ++ S S N S
Sbjct: 499 TQRRKHASSIKDLTKQLQQARRKLDQVESGSYDKEVSSMGSRSSSSGS----LNARSSAE 554
Query: 375 DDESENTYERISL----TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD 424
D ENT +++ +DK + Q +KN+ + + + KQ+ +
Sbjct: 555 DRSPENTGSSVAVDNFPQVDKAMLIERIVRLQKAHARKNEKIEFMEDHIKQLVE 608
Score = 41.1 bits (92), Expect = 0.009
Identities = 66/346 (19%), Positives = 146/346 (42%), Gaps = 33/346 (9%)
Query: 198 NTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFI 257
N +++LF + + +K N +E + E Q++ +RDK I
Sbjct: 33 NKKHQELFVDICS--EKDNLREELKKRTETEKQHMNTIKQLESRIEELNKEVKASRDKLI 90
Query: 258 ANLEEMKTMLVE------EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL- 310
A K + + +++ + +K E +QE + + K + +E + +EK L
Sbjct: 91 AQDVTAKNAVQQLHKEMAQRMEQANKKCEEARQEKEAMVMKYVRGEKESLDLRKEKETLE 150
Query: 311 --LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKI- 366
L D +K++ K ++++ ++ L + E + +LI + I S K+
Sbjct: 151 KKLRDANKELEKNTNKIKQLSQEKGRLHQLYETKEGETTRLIREIDKLKEDINSHVIKVK 210
Query: 367 --SNQLSCELDDESENTYERISLTLDKIT----------NHITYLNTQINETQKNDNAQL 414
N+L E+D E T +++ T K+T + + E+++ + +L
Sbjct: 211 WAQNKLKAEMDSHKE-TKDKLKETTTKLTQAKEEADQIRKNCQDMIKTYQESEEIKSNEL 269
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXX 474
+ + +L +Q ++E+ QLE + ++ E++ ++ + +E L+ T
Sbjct: 270 DAKLRVTKGELEKQ---MQEKSDQLEMHHAKIK-ELEDLKRTFKEGMDELRTLRTKVKCL 325
Query: 475 XXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMK---QQQKELKLGK 517
+E+ K + K++ ++L D +K Q Q++L+ GK
Sbjct: 326 EDERLRTEDELSKYKEIINRQKAEIQNLLDKVKTADQLQEQLQRGK 371
>X51593-1|CAA35942.1| 1085|Homo sapiens embryonic myosin heavy chain
(1085 AA) protein.
Length = 1085
Score = 57.2 bits (132), Expect = 1e-07
Identities = 98/464 (21%), Positives = 188/464 (40%), Gaps = 39/464 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEV-------I 134
++L +E K +L++ E L+ + +Q + +++ E D L + I
Sbjct: 7 DELAKSEAKRKELEEKLVTLVQEKNDLQLQ-VQAESENLLDAEERCDQLIKAKFQLEAKI 65
Query: 135 NTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYLE 191
+T E EE+ E+ KK + + +K +D L + K E + + N +K L
Sbjct: 66 KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 125
Query: 192 SVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXXX 249
S + KL + A+ Q Q+ +D L+ E N L
Sbjct: 126 EELSGLDETIAKLTRE-KKAL--QEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 182
Query: 250 XXARDKFI-ANLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQE 306
++K + +LE K L + KL++ D EN KQ++D +K + + +++
Sbjct: 183 SLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVED 242
Query: 307 KNILLSDLSKKVNKTERELEEKQEQL-------THLMEQLNDTENNSYKLIENMFNKVSQ 359
+ L KK+ + + +EE +E++ +Q +D +L E +
Sbjct: 243 EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGV 302
Query: 360 IASDFKISNQLSCEL-----D-DESENTYERISLTL-DKITNHITYLNTQINETQ--KND 410
++ +++ + E D +E+ +E + TL K + + L QI+ Q K
Sbjct: 303 TSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQK 362
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTX 470
+ E K +I DL+ + + + LE + L ++ RG NEE+ +L + +T
Sbjct: 363 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQ 422
Query: 471 XXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
S ++E+ ++ V SQ QQ +ELK
Sbjct: 423 KSRLQTEAGELSRQLEEKESIV----SQLSRSKQAFTQQTEELK 462
Score = 48.4 bits (110), Expect = 6e-05
Identities = 69/363 (19%), Positives = 150/363 (41%), Gaps = 25/363 (6%)
Query: 81 TEKLTIAETKHNDLKKLYEDSASELEALK---------RENIQMHTSDVMVVPEIIDSLT 131
TE+L A+ K L + +DS ++EA+ ++ +Q D+MV E +SL
Sbjct: 529 TEELEEAKKK---LAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 585
Query: 132 EVINTLTNGFESL----EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
++ F+ + + E + + K++ S+ T L KL E +++L
Sbjct: 586 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 645
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
+ ++++ E E++ E + + +++++L K + Q L+
Sbjct: 646 RENKNLEQEIADLTEQIAEN-GKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKI 704
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
+ + + K + EK EI++ N+++ ++ + L + R NE ++ K
Sbjct: 705 LRIQLELTQVKSEIDRK---IAEKDEEIEQLKRNYQRTVETMQSALDAEVRRANEAIRLK 761
Query: 308 NILLSDLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+ DL++ +++ R+ E + L + QL DT+ + + + Q+A
Sbjct: 762 KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVE 821
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD 424
+ +N L E+ +E T E+ + N ++ + N L+ KK D
Sbjct: 822 RRANLLQAEV-EELRATLEQTERARKLAEQELLDSNERV-QLLHTQNTSLIHTKKKLETD 879
Query: 425 LTE 427
L +
Sbjct: 880 LMQ 882
Score = 46.0 bits (104), Expect = 3e-04
Identities = 93/499 (18%), Positives = 196/499 (39%), Gaps = 34/499 (6%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
F+ +++E I +L+ ++ KT E + + + +L
Sbjct: 250 FQKKIKELQARIEELEEEIEAERATRAKT--EKQRSDYARELEELSERLEEAGGVTSTQI 307
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E E + L++ E++ + EA+ + H V + E ID+L V L
Sbjct: 308 ELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLE--- 364
Query: 142 ESLEEVALEID---LKKNSITKDNISIKTL---LDKLITKNETDINELRNSIKYLESVKS 195
+ E LEID S++K +++ + L+ +++ E++ S+ L + KS
Sbjct: 365 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 424
Query: 196 EYNTANEKLFEQLNN--------AVDKQNCIQEEVDLLK-IENQNLLQXXXXXXXXXXXX 246
T +L QL + KQ Q+ +L + +E +N +
Sbjct: 425 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALGHALQSSRH 484
Query: 247 XXXXXARDKFIANLE---EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
R+++ E E++ L + SE+ + ++ + E+L +++ +
Sbjct: 485 DCDLL-REQYEEEQEGKAELQRALSKAN-SEVAQWRTKYETDAIQRTEELEEAKKKLAQR 542
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+Q+ + ++ K E+ + Q ++ LM + + N+ ++ ++ ++
Sbjct: 543 LQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDV-ERANSLAAALDKKQRNFDKVLAE 601
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
+K + S + S +S L K+ N Q+ ET K +N L +++IA
Sbjct: 602 WKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL-ETVKRENKNL----EQEIA 656
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
DLTEQ + + +LE K++ +E ++ + EE L+ +
Sbjct: 657 DLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 716
Query: 484 EIEDMKTKVMEWKSQFEDL 502
EI+ K+ E + E L
Sbjct: 717 EID---RKIAEKDEEIEQL 732
Score = 43.6 bits (98), Expect = 0.002
Identities = 38/200 (19%), Positives = 91/200 (45%), Gaps = 3/200 (1%)
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE 379
K+E + +E +E+L L+++ ND + EN+ + + K QL ++ + +E
Sbjct: 11 KSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTE 70
Query: 380 NTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAKKQIADLTEQNII-LKERLS 437
+ + + +T L + +E +K+ D+ +L ++ TE + L E LS
Sbjct: 71 RAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELS 129
Query: 438 QLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKS 497
L+ +L E + ++ ++++ +L+ ++ED+++ + + K
Sbjct: 130 GLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKK 189
Query: 498 QFEDLDDVMKQQQKELKLGK 517
DL+ ++ + +LKL +
Sbjct: 190 LRVDLERNKRKLEGDLKLAQ 209
Score = 38.3 bits (85), Expect = 0.065
Identities = 75/426 (17%), Positives = 179/426 (42%), Gaps = 37/426 (8%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES--LEEVALEI 151
LK YE++ +LE +KREN + ++ + E I + I+ L + LE+ +++
Sbjct: 630 LKNAYEEALDQLETVKRENKNLE-QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQL 688
Query: 152 DLKKNSITKDNISIKTLLDKL-ITKNETDIN-ELRNSIKYLESVKSEYNTANEKLFEQLN 209
L++ ++ K L +L +T+ +++I+ ++ + +E +K Y E + L+
Sbjct: 689 ALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNYQRTVETMQSALD 748
Query: 210 NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
V + N E + L K +L + + +L ++ L +
Sbjct: 749 AEVRRAN---EAIRLKKKMEGDLNEIEIQLSHANRQAAET-------LKHLRSVQGQLKD 798
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRRE--FNETMQEKNILLSDLSKKVNKTERELEE 327
+L D+ + + D+ + I +RR ++E L + E+EL +
Sbjct: 799 TQL----HLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 854
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
E++ L+ N + ++ K +E + Q+ S+ + +++ + +++++ ++
Sbjct: 855 SNERV-QLLHTQNTSLIHTKKKLET---DLMQLQSEVEDASRDARNAEEKAKKAITDAAM 910
Query: 388 TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL--KERLSQLETENKE 445
+++ +T + + N + + + D EQ + K+++ +LET +E
Sbjct: 911 MAEELKKE---QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRE 967
Query: 446 LLIEIQTVRGSNEEVTLNL-------KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
L E++ + N E L K+ + + ++ ++ KV +K Q
Sbjct: 968 LEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQ 1027
Query: 499 FEDLDD 504
E+ D+
Sbjct: 1028 AEEADE 1033
>X51592-1|CAA35941.1| 1437|Homo sapiens fetal-myosin heavy chain
(1437 AA) protein.
Length = 1437
Score = 57.2 bits (132), Expect = 1e-07
Identities = 77/422 (18%), Positives = 168/422 (39%), Gaps = 18/422 (4%)
Query: 43 NVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAE--TKHNDLKKLYED 100
N+ KT E + D++ + Q L L +A+ T N+ K D
Sbjct: 520 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDNENDKQQLD 579
Query: 101 SASELEALKRENIQMHTSDVMVVP----EIIDSLTEVINTLTNGFESLEEVALEIDLKKN 156
E + + N+ D V + I L I L E+ + + +++
Sbjct: 580 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 639
Query: 157 SITKDNISIKTLLDKL--ITKNETDINELRNS-IKYLESVKSEYNTANEKLFEQLNNA-V 212
++++ I L++ T + ++N+ R + + L E +E + L
Sbjct: 640 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 699
Query: 213 DKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKL 272
D + E++D L+ Q L + A K NLE+ +E+++
Sbjct: 700 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKDGGRSLEDQV 759
Query: 273 SEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
SE+K K+E ++ I+ L +L + E++ + EK+ L+S LS+ + +++EE
Sbjct: 760 SELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEE-- 817
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
L H +E+ +N +++ + + ++ + EL ++
Sbjct: 818 --LKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWR 875
Query: 390 DKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIE 449
++ E +K AQ L EA++ + + + L++ +L+ E ++L+++
Sbjct: 876 TNTETDAIQRTEELEEAKKK-LAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 934
Query: 450 IQ 451
++
Sbjct: 935 VE 936
Score = 44.4 bits (100), Expect = 0.001
Identities = 90/465 (19%), Positives = 196/465 (42%), Gaps = 34/465 (7%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q +++V + A L+ + + + + L L +K
Sbjct: 889 LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKK 948
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
+ ++ K+ YE++ +ELEA ++E+ + T ++ V + + + + TL ++
Sbjct: 949 QRNFDKVLSEWKQKYEETQAELEASQKESRSLST-ELFKVKNVYEESLDQLETLRRENKN 1007
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLE-SVKSEYNTANE 202
L++ EI I + I L+K+ + E + E++ +++ E S++ E
Sbjct: 1008 LQQ---EISDLTEQIAEGGKQIHE-LEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILR 1063
Query: 203 KLFE--QLNNAVDKQNCIQ-EEVDLLKIENQNLLQX-XXXXXXXXXXXXXXXXARDKFIA 258
E Q+ + VD++ + EE+D LK + +++ + K
Sbjct: 1064 IQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEG 1123
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL--ICDRREFNETMQEK--------N 308
+L EM+ L E N++ +L E + D E ++E+ N
Sbjct: 1124 DLNEMEIQL-NHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRAN 1182
Query: 309 IL---LSDLSKKVNKTERELEEKQEQLTHLME--QLNDTENNS-YKLIENMFNKVSQIAS 362
+L + +L + +TER + +++L E QL T+N S + + N VSQ+ S
Sbjct: 1183 LLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQS 1242
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
+ + Q S +++++ ++ +++ +T + + N + + +
Sbjct: 1243 EVEEVIQESRNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNLEQTVKDLQHR 1299
Query: 423 ADLTEQNIIL--KERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
D EQ + K+++ +LE +EL E++ + N E L+
Sbjct: 1300 LDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLR 1344
Score = 43.6 bits (98), Expect = 0.002
Identities = 64/327 (19%), Positives = 142/327 (43%), Gaps = 39/327 (11%)
Query: 190 LESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXX 249
LE+ + E + + +LF+ + N ++ ++++ L+ EN+NL Q
Sbjct: 970 LEASQKESRSLSTELFK-VKNVYEES---LDQLETLRRENKNLQQEISDLTEQIAEGG-- 1023
Query: 250 XXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNI 309
K I LE++K + +EK EI+ E + ++ K++ + E N+
Sbjct: 1024 -----KQIHELEKIKKQVEQEKC-EIQAALEEAEASLEHEEGKILRIQLELNQ------- 1070
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
+ S++ +K+ + + E+++ + T ++E + T + + + ++ D N+
Sbjct: 1071 VKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDL---NE 1127
Query: 370 LSCELDDESENTYERISLTLDKITNHITYLNTQ--INETQKNDNAQLLWEAKKQIADLTE 427
+ +L+ + L + + N Y NTQ + ETQ + L +A + DL E
Sbjct: 1128 MEIQLNHANR-------LAAESLRN---YRNTQGILKETQLH-----LDDALRGQEDLKE 1172
Query: 428 QNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED 487
Q I++ R + L+ E +EL ++ S + L D+S N +
Sbjct: 1173 QLAIVERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1232
Query: 488 MKTKVMEWKSQFEDLDDVMKQQQKELK 514
++ V + +S+ E++ + +++ K
Sbjct: 1233 LENDVSQLQSEVEEVIQESRNAEEKAK 1259
Score = 37.5 bits (83), Expect = 0.11
Identities = 37/221 (16%), Positives = 99/221 (44%), Gaps = 6/221 (2%)
Query: 302 ETMQEKNILLSDLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
ET +E + + K ++ K+E + +E +E++ L+++ ND + +++ +
Sbjct: 346 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEE 405
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWE 417
+ K QL ++ + +E E + + +T L + +E +K+ D+ +L
Sbjct: 406 RCEQLIKNKIQLEAKIKEVTERAEEEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLA 464
Query: 418 AKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXX 476
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 465 KVEKEKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTK 524
Query: 477 XXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+++D++ + + K DL+ ++ + +LKL +
Sbjct: 525 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 565
Score = 32.7 bits (71), Expect = 3.2
Identities = 50/264 (18%), Positives = 107/264 (40%), Gaps = 15/264 (5%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L E+L I E + N L+ E+ + LE +R ++ +++ E + L +L N
Sbjct: 1170 LKEQLAIVERRANLLQAEIEELWATLEQTERSR-KIAEQELLDASERVQLLHTQNTSLIN 1228
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR---NSIKYLESVKSE 196
+ LE ++ + + +++ + + K IT EL+ ++ +LE +K
Sbjct: 1229 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1288
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
+ L +L+ A +Q ++ ++ + + K
Sbjct: 1289 LEQTVKDLQHRLDEA--EQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKH 1346
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
++E+ E++ + ++ +D +D L K+ +R+ E ++ N LS
Sbjct: 1347 ERRVKELTYQTEEDRKNVLRLQDL-----VDKLQAKVKSYKRQAEEAEEQSNANLS---- 1397
Query: 317 KVNKTERELEEKQEQLTHLMEQLN 340
K K + ELEE +E+ Q+N
Sbjct: 1398 KFRKLQHELEEAEERADIAESQVN 1421
>X15696-1|CAA33731.1| 1085|Homo sapiens protein ( Human muscle mRNA
for embryonic myosin heavy chain (SMHCE). ).
Length = 1085
Score = 57.2 bits (132), Expect = 1e-07
Identities = 98/464 (21%), Positives = 188/464 (40%), Gaps = 39/464 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEV-------I 134
++L +E K +L++ E L+ + +Q + +++ E D L + I
Sbjct: 7 DELAKSEAKRKELEEKLVTLVQEKNDLQLQ-VQAESENLLDAEERCDQLIKAKFQLEAKI 65
Query: 135 NTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYLE 191
+T E EE+ E+ KK + + +K +D L + K E + + N +K L
Sbjct: 66 KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 125
Query: 192 SVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXXX 249
S + KL + A+ Q Q+ +D L+ E N L
Sbjct: 126 EELSGLDETIAKLTRE-KKAL--QEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 182
Query: 250 XXARDKFI-ANLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQE 306
++K + +LE K L + KL++ D EN KQ++D +K + + +++
Sbjct: 183 SLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVED 242
Query: 307 KNILLSDLSKKVNKTERELEEKQEQL-------THLMEQLNDTENNSYKLIENMFNKVSQ 359
+ L KK+ + + +EE +E++ +Q +D +L E +
Sbjct: 243 EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGV 302
Query: 360 IASDFKISNQLSCEL-----D-DESENTYERISLTL-DKITNHITYLNTQINETQ--KND 410
++ +++ + E D +E+ +E + TL K + + L QI+ Q K
Sbjct: 303 TSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQK 362
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTX 470
+ E K +I DL+ + + + LE + L ++ RG NEE+ +L + +T
Sbjct: 363 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQ 422
Query: 471 XXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
S ++E+ ++ V SQ QQ +ELK
Sbjct: 423 KSRLQTEAGELSRQLEEKESIV----SQLSRSKQAFTQQTEELK 462
Score = 48.0 bits (109), Expect = 8e-05
Identities = 69/363 (19%), Positives = 150/363 (41%), Gaps = 25/363 (6%)
Query: 81 TEKLTIAETKHNDLKKLYEDSASELEALK---------RENIQMHTSDVMVVPEIIDSLT 131
TE+L A+ K L + +DS ++EA+ ++ +Q D+MV E +SL
Sbjct: 529 TEELEEAKKK---LAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 585
Query: 132 EVINTLTNGFESL----EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
++ F+ + + E + + K++ S+ T L KL E +++L
Sbjct: 586 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 645
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
+ ++++ E E++ E + + +++++L K + Q L+
Sbjct: 646 RENKNLEQEIADLTEQIAEN-GKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKI 704
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
+ + + K + EK EI++ N+++ ++ + L + R NE ++ K
Sbjct: 705 LRIQLELTQVKSEIDRK---IAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLK 761
Query: 308 NILLSDLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+ DL++ +++ R+ E + L + QL DT+ + + + Q+A
Sbjct: 762 KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVE 821
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD 424
+ +N L E+ +E T E+ + N ++ + N L+ KK D
Sbjct: 822 RRANLLQAEV-EELRATLEQTERARKLAEQELLDSNERV-QLLHTQNTSLIHTKKKLETD 879
Query: 425 LTE 427
L +
Sbjct: 880 LMQ 882
Score = 46.4 bits (105), Expect = 2e-04
Identities = 93/499 (18%), Positives = 196/499 (39%), Gaps = 34/499 (6%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
F+ +++E I +L+ ++ KT E + + + +L
Sbjct: 250 FQKKIKELQARIEELEEEIEAERATRAKT--EKQRSDYARELEELSERLEEAGGVTSTQI 307
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E E + L++ E++ + EA+ + H V + E ID+L V L
Sbjct: 308 ELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLE--- 364
Query: 142 ESLEEVALEID---LKKNSITKDNISIKTL---LDKLITKNETDINELRNSIKYLESVKS 195
+ E LEID S++K +++ + L+ +++ E++ S+ L + KS
Sbjct: 365 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 424
Query: 196 EYNTANEKLFEQLNN--------AVDKQNCIQEEVDLLK-IENQNLLQXXXXXXXXXXXX 246
T +L QL + KQ Q+ +L + +E +N +
Sbjct: 425 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 484
Query: 247 XXXXXARDKFIANLE---EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
R+++ E E++ L + SE+ + ++ + E+L +++ +
Sbjct: 485 DCDLL-REQYEEEQEGKAELQRALSKAN-SEVAQWRTKYETDAIQRTEELEEAKKKLAQR 542
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+Q+ + ++ K E+ + Q ++ LM + + N+ ++ ++ ++
Sbjct: 543 LQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDV-ERANSLAAALDKKQRNFDKVLAE 601
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
+K + S + S +S L K+ N Q+ ET K +N L +++IA
Sbjct: 602 WKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL-ETVKRENKNL----EQEIA 656
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
DLTEQ + + +LE K++ +E ++ + EE L+ +
Sbjct: 657 DLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 716
Query: 484 EIEDMKTKVMEWKSQFEDL 502
EI+ K+ E + E L
Sbjct: 717 EID---RKIAEKDEEIEQL 732
Score = 43.6 bits (98), Expect = 0.002
Identities = 38/200 (19%), Positives = 91/200 (45%), Gaps = 3/200 (1%)
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE 379
K+E + +E +E+L L+++ ND + EN+ + + K QL ++ + +E
Sbjct: 11 KSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQLEAKIKEVTE 70
Query: 380 NTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAKKQIADLTEQNII-LKERLS 437
+ + + +T L + +E +K+ D+ +L ++ TE + L E LS
Sbjct: 71 RAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEELS 129
Query: 438 QLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKS 497
L+ +L E + ++ ++++ +L+ ++ED+++ + + K
Sbjct: 130 GLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKK 189
Query: 498 QFEDLDDVMKQQQKELKLGK 517
DL+ ++ + +LKL +
Sbjct: 190 LRVDLERNKRKLEGDLKLAQ 209
Score = 39.1 bits (87), Expect = 0.037
Identities = 74/426 (17%), Positives = 181/426 (42%), Gaps = 37/426 (8%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES--LEEVALEI 151
LK YE++ +LE +KREN + ++ + E I + I+ L + LE+ +++
Sbjct: 630 LKNAYEEALDQLETVKRENKNLE-QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQL 688
Query: 152 DLKKNSITKDNISIKTLLDKL-ITKNETDIN-ELRNSIKYLESVKSEYNTANEKLFEQLN 209
L++ ++ K L +L +T+ +++I+ ++ + +E +K Y ++ E +
Sbjct: 689 ALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNY----QRTVETMQ 744
Query: 210 NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
+A+D + + E LK + + L + +L ++ L +
Sbjct: 745 SALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAET------LKHLRSVQGQLKD 798
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRRE--FNETMQEKNILLSDLSKKVNKTERELEE 327
+L D+ + + D+ + I +RR ++E L + E+EL +
Sbjct: 799 TQL----HLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 854
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
E++ L+ N + ++ K +E + Q+ S+ + +++ + +++++ ++
Sbjct: 855 SNERV-QLLHTQNTSLIHTKKKLET---DLMQLQSEVEDASRDARNAEEKAKKAITDAAM 910
Query: 388 TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL--KERLSQLETENKE 445
+++ +T + + N + + + D EQ + K+++ +LET +E
Sbjct: 911 MAEELKKE---QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRE 967
Query: 446 LLIEIQTVRGSNEEVTLNL-------KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
L E++ + N E L K+ + + ++ ++ KV +K Q
Sbjct: 968 LEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQ 1027
Query: 499 FEDLDD 504
E+ D+
Sbjct: 1028 AEEADE 1033
>X13988-1|CAA32167.1| 1940|Homo sapiens protein ( Human mRNA for
embryonic myosin heavy chain. ).
Length = 1940
Score = 57.2 bits (132), Expect = 1e-07
Identities = 98/464 (21%), Positives = 188/464 (40%), Gaps = 39/464 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEV-------I 134
++L +E K +L++ E L+ + +Q + +++ E D L + I
Sbjct: 862 DELAKSEAKRKELEEKLVTLVQEKNDLQLQ-VQAESENLLDAEERCDQLIKAKFQLEAKI 920
Query: 135 NTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYLE 191
+T E EE+ E+ KK + + +K +D L + K E + + N +K L
Sbjct: 921 KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 980
Query: 192 SVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXXX 249
S + KL + A+ Q Q+ +D L+ E N L
Sbjct: 981 EELSGLDETIAKLTRE-KKAL--QEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 1037
Query: 250 XXARDKFI-ANLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQE 306
++K + +LE K L + KL++ D EN KQ++D +K + + +++
Sbjct: 1038 SLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVED 1097
Query: 307 KNILLSDLSKKVNKTERELEEKQEQL-------THLMEQLNDTENNSYKLIENMFNKVSQ 359
+ L KK+ + + +EE +E++ +Q +D +L E +
Sbjct: 1098 EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGV 1157
Query: 360 IASDFKISNQLSCEL-----D-DESENTYERISLTL-DKITNHITYLNTQINETQ--KND 410
++ +++ + E D +E+ +E + TL K + + L QI+ Q K
Sbjct: 1158 TSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQK 1217
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTX 470
+ E K +I DL+ + + + LE + L ++ RG NEE+ +L + +T
Sbjct: 1218 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQ 1277
Query: 471 XXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
S ++E+ ++ V SQ QQ +ELK
Sbjct: 1278 KSRLQTEAGELSRQLEEKESIV----SQLSRSKQAFTQQTEELK 1317
Score = 48.4 bits (110), Expect = 6e-05
Identities = 69/363 (19%), Positives = 150/363 (41%), Gaps = 25/363 (6%)
Query: 81 TEKLTIAETKHNDLKKLYEDSASELEALK---------RENIQMHTSDVMVVPEIIDSLT 131
TE+L A+ K L + +DS ++EA+ ++ +Q D+MV E +SL
Sbjct: 1384 TEELEEAQEK---LAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 1440
Query: 132 EVINTLTNGFESL----EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
++ F+ + + E + + K++ S+ T L KL E +++L
Sbjct: 1441 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 1500
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
+ ++++ E E++ E + + +++++L K + Q L+
Sbjct: 1501 RENKNLEQEIADLTEQIAEN-GKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKI 1559
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
+ + + K + EK EI++ N+++ ++ + L + R NE ++ K
Sbjct: 1560 LRIQLELTQVKSEIDRK---IAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLK 1616
Query: 308 NILLSDLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+ DL++ +++ R+ E + L + QL DT+ + + + Q+A
Sbjct: 1617 KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVE 1676
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD 424
+ +N L E+ +E T E+ + N ++ + N L+ KK D
Sbjct: 1677 RRANLLQAEV-EELRATLEQTERARKLAEQELLDSNERV-QLLHTQNTSLIHTKKKLETD 1734
Query: 425 LTE 427
L +
Sbjct: 1735 LMQ 1737
Score = 45.2 bits (102), Expect = 6e-04
Identities = 93/499 (18%), Positives = 195/499 (39%), Gaps = 34/499 (6%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
F+ +++E I +L+ ++ KT E + + + +L
Sbjct: 1105 FQKKIKELQARIEELEEEIEAERATRAKT--EKQRSDYARELEELSERLEEAGGVTSTQI 1162
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E E + L++ E++ + EA+ + H V + E ID+L V L
Sbjct: 1163 ELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLE--- 1219
Query: 142 ESLEEVALEID---LKKNSITKDNISIKTL---LDKLITKNETDINELRNSIKYLESVKS 195
+ E LEID S++K +++ + L+ +++ E++ S+ L + KS
Sbjct: 1220 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 1279
Query: 196 EYNTANEKLFEQLNN--------AVDKQNCIQEEVDLLK-IENQNLLQXXXXXXXXXXXX 246
T +L QL + KQ Q+ +L + +E +N +
Sbjct: 1280 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 1339
Query: 247 XXXXXARDKFIANLE---EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
R+++ E E++ L + SE+ + ++ + E+L + + +
Sbjct: 1340 DCDLL-REQYEEEQEGKAELQRALSKAN-SEVAQWRTKYETDAIQRTEELEEAQEKLAQR 1397
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+Q+ + ++ K E+ + Q ++ LM + + N+ ++ ++ ++
Sbjct: 1398 LQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDV-ERANSLAAALDKKQRNFDKVLAE 1456
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
+K + S + S +S L K+ N Q+ ET K +N L +++IA
Sbjct: 1457 WKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL-ETVKRENKNL----EQEIA 1511
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
DLTEQ + + +LE K++ +E ++ + EE L+ +
Sbjct: 1512 DLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 1571
Query: 484 EIEDMKTKVMEWKSQFEDL 502
EI+ K+ E + E L
Sbjct: 1572 EID---RKIAEKDEEIEQL 1587
Score = 44.4 bits (100), Expect = 0.001
Identities = 42/221 (19%), Positives = 100/221 (45%), Gaps = 6/221 (2%)
Query: 302 ETMQEKNILLSDLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
ET +E + + K ++ K+E + +E +E+L L+++ ND + EN+ +
Sbjct: 845 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEE 904
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWE 417
+ K QL ++ + +E + + + +T L + +E +K+ D+ +L
Sbjct: 905 RCDQLIKAKFQLEAKIKEVTERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLA 963
Query: 418 AKKQIADLTEQNII-LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXX 476
++ TE + L E LS L+ +L E + ++ ++++ +L+
Sbjct: 964 KVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNK 1023
Query: 477 XXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
++ED+++ + + K DL+ ++ + +LKL +
Sbjct: 1024 TKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQ 1064
Score = 39.1 bits (87), Expect = 0.037
Identities = 74/426 (17%), Positives = 181/426 (42%), Gaps = 37/426 (8%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES--LEEVALEI 151
LK YE++ +LE +KREN + ++ + E I + I+ L + LE+ +++
Sbjct: 1485 LKNAYEEALDQLETVKRENKNLE-QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQL 1543
Query: 152 DLKKNSITKDNISIKTLLDKL-ITKNETDIN-ELRNSIKYLESVKSEYNTANEKLFEQLN 209
L++ ++ K L +L +T+ +++I+ ++ + +E +K Y ++ E +
Sbjct: 1544 ALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNY----QRTVETMQ 1599
Query: 210 NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
+A+D + + E LK + + L + +L ++ L +
Sbjct: 1600 SALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAET------LKHLRSVQGQLKD 1653
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRRE--FNETMQEKNILLSDLSKKVNKTERELEE 327
+L D+ + + D+ + I +RR ++E L + E+EL +
Sbjct: 1654 TQL----HLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 1709
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
E++ L+ N + ++ K +E + Q+ S+ + +++ + +++++ ++
Sbjct: 1710 SNERV-QLLHTQNTSLIHTKKKLET---DLMQLQSEVEDASRDARNAEEKAKKAITDAAM 1765
Query: 388 TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL--KERLSQLETENKE 445
+++ +T + + N + + + D EQ + K+++ +LET +E
Sbjct: 1766 MAEELKKE---QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRE 1822
Query: 446 LLIEIQTVRGSNEEVTLNL-------KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
L E++ + N E L K+ + + ++ ++ KV +K Q
Sbjct: 1823 LEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQ 1882
Query: 499 FEDLDD 504
E+ D+
Sbjct: 1883 AEEADE 1888
>X13100-1|CAA31492.1| 1167|Homo sapiens myosin heavy chain (1167 AA)
protein.
Length = 1167
Score = 57.2 bits (132), Expect = 1e-07
Identities = 98/464 (21%), Positives = 188/464 (40%), Gaps = 39/464 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEV-------I 134
++L +E K +L++ E L+ + +Q + +++ E D L + I
Sbjct: 89 DELAKSEAKRKELEEKLVTLVQEKNDLQLQ-VQAESENLLDAEERCDQLIKAKFQLEAKI 147
Query: 135 NTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYLE 191
+T E EE+ E+ KK + + +K +D L + K E + + N +K L
Sbjct: 148 KEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 207
Query: 192 SVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXXX 249
S + KL + A+ Q Q+ +D L+ E N L
Sbjct: 208 EELSGLDETIAKLTRE-KKAL--QEAHQQALDDLQAEEDKVNSLNKTKSKLEQQVEDLES 264
Query: 250 XXARDKFI-ANLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQE 306
++K + +LE K L + KL++ D EN KQ++D +K + + +++
Sbjct: 265 SLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVED 324
Query: 307 KNILLSDLSKKVNKTERELEEKQEQL-------THLMEQLNDTENNSYKLIENMFNKVSQ 359
+ L KK+ + + +EE +E++ +Q +D +L E +
Sbjct: 325 EQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGV 384
Query: 360 IASDFKISNQLSCEL-----D-DESENTYERISLTL-DKITNHITYLNTQINETQ--KND 410
++ +++ + E D +E+ +E + TL K + + L QI+ Q K
Sbjct: 385 TSTQIELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQK 444
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTX 470
+ E K +I DL+ + + + LE + L ++ RG NEE+ +L + +T
Sbjct: 445 LEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQ 504
Query: 471 XXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
S ++E+ ++ V SQ QQ +ELK
Sbjct: 505 KSRLQTEAGELSRQLEEKESIV----SQLSRSKQAFTQQTEELK 544
Score = 49.2 bits (112), Expect = 3e-05
Identities = 69/363 (19%), Positives = 151/363 (41%), Gaps = 25/363 (6%)
Query: 81 TEKLTIAETKHNDLKKLYEDSASELEALK---------RENIQMHTSDVMVVPEIIDSLT 131
TE+L A+ K L + +DS ++EA+ ++ +Q D+MV E +SL
Sbjct: 611 TEELEEAQEK---LAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 667
Query: 132 EVINTLTNGFESL----EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
++ F+ + + E + + K++ S+ T L KL E +++L
Sbjct: 668 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 727
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
+ ++++ E E++ E + + +++++L K + Q L+
Sbjct: 728 RENKNLEQEIADLTEQIAEN-GKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKI 786
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
+ + + K + EK EI++ N+++ ++ + L + R NE ++ K
Sbjct: 787 LRIQLELTQVKSEIDRK---IAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLK 843
Query: 308 NILLSDLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+ DL++ +++ R+ E + L + QL DT+ + ++ + Q+A
Sbjct: 844 KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALQTQEDLKEQLAIVE 903
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD 424
+ +N L E+ +E T E+ + N ++ + N L+ KK D
Sbjct: 904 RRANLLQAEV-EELRATLEQTERARKLAEQELLDSNERV-QLLHTQNTSLIHTKKKLETD 961
Query: 425 LTE 427
L +
Sbjct: 962 LMQ 964
Score = 45.2 bits (102), Expect = 6e-04
Identities = 93/499 (18%), Positives = 195/499 (39%), Gaps = 34/499 (6%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
F+ +++E I +L+ ++ KT E + + + +L
Sbjct: 332 FQKKIKELQARIEELEEEIEAERATRAKT--EKQRSDYARELEELSERLEEAGGVTSTQI 389
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E E + L++ E++ + EA+ + H V + E ID+L V L
Sbjct: 390 ELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLE--- 446
Query: 142 ESLEEVALEID---LKKNSITKDNISIKTL---LDKLITKNETDINELRNSIKYLESVKS 195
+ E LEID S++K +++ + L+ +++ E++ S+ L + KS
Sbjct: 447 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 506
Query: 196 EYNTANEKLFEQLNN--------AVDKQNCIQEEVDLLK-IENQNLLQXXXXXXXXXXXX 246
T +L QL + KQ Q+ +L + +E +N +
Sbjct: 507 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 566
Query: 247 XXXXXARDKFIANLE---EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
R+++ E E++ L + SE+ + ++ + E+L + + +
Sbjct: 567 DCDLL-REQYEEEQEGKAELQRALSKAN-SEVAQWRTKYETDAIQRTEELEEAQEKLAQR 624
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+Q+ + ++ K E+ + Q ++ LM + + N+ ++ ++ ++
Sbjct: 625 LQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDV-ERANSLAAALDKKQRNFDKVLAE 683
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
+K + S + S +S L K+ N Q+ ET K +N L +++IA
Sbjct: 684 WKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL-ETVKRENKNL----EQEIA 738
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
DLTEQ + + +LE K++ +E ++ + EE L+ +
Sbjct: 739 DLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 798
Query: 484 EIEDMKTKVMEWKSQFEDL 502
EI+ K+ E + E L
Sbjct: 799 EID---RKIAEKDEEIEQL 814
Score = 44.4 bits (100), Expect = 0.001
Identities = 42/221 (19%), Positives = 100/221 (45%), Gaps = 6/221 (2%)
Query: 302 ETMQEKNILLSDLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
ET +E + + K ++ K+E + +E +E+L L+++ ND + EN+ +
Sbjct: 72 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEE 131
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWE 417
+ K QL ++ + +E + + + +T L + +E +K+ D+ +L
Sbjct: 132 RCDQLIKAKFQLEAKIKEVTERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLA 190
Query: 418 AKKQIADLTEQNII-LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXX 476
++ TE + L E LS L+ +L E + ++ ++++ +L+
Sbjct: 191 KVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAHQQALDDLQAEEDKVNSLNK 250
Query: 477 XXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
++ED+++ + + K DL+ ++ + +LKL +
Sbjct: 251 TKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQ 291
Score = 39.1 bits (87), Expect = 0.037
Identities = 74/426 (17%), Positives = 181/426 (42%), Gaps = 37/426 (8%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES--LEEVALEI 151
LK YE++ +LE +KREN + ++ + E I + I+ L + LE+ +++
Sbjct: 712 LKNAYEEALDQLETVKRENKNLE-QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQL 770
Query: 152 DLKKNSITKDNISIKTLLDKL-ITKNETDIN-ELRNSIKYLESVKSEYNTANEKLFEQLN 209
L++ ++ K L +L +T+ +++I+ ++ + +E +K Y ++ E +
Sbjct: 771 ALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNY----QRTVETMQ 826
Query: 210 NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
+A+D + + E LK + + L + +L ++ L +
Sbjct: 827 SALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAET------LKHLRSVQGQLKD 880
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRRE--FNETMQEKNILLSDLSKKVNKTERELEE 327
+L D+ + + D+ + I +RR ++E L + E+EL +
Sbjct: 881 TQL----HLDDALQTQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 936
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
E++ L+ N + ++ K +E + Q+ S+ + +++ + +++++ ++
Sbjct: 937 SNERV-QLLHTQNTSLIHTKKKLET---DLMQLQSEVEDASRDARNAEEKAKKAITDAAM 992
Query: 388 TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL--KERLSQLETENKE 445
+++ +T + + N + + + D EQ + K+++ +LET +E
Sbjct: 993 MAEELKKE---QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRE 1049
Query: 446 LLIEIQTVRGSNEEVTLNL-------KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
L E++ + N E L K+ + + ++ ++ KV +K Q
Sbjct: 1050 LEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQ 1109
Query: 499 FEDLDD 504
E+ D+
Sbjct: 1110 AEEADE 1115
>AB059622-1|BAB69690.1| 1594|Homo sapiens Rb1-inducible coiled coil
protein protein.
Length = 1594
Score = 57.2 bits (132), Expect = 1e-07
Identities = 70/381 (18%), Positives = 169/381 (44%), Gaps = 30/381 (7%)
Query: 146 EVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS-----IKYLESVKSEYNTA 200
E+ LE DLKK + D ++ L +L + ++ + EL ++ I+ E V +++ +
Sbjct: 956 EIVLE-DLKKLHVENDE-KLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVS 1013
Query: 201 NEKLF---EQLNNAVDKQNC--IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
E+L +Q+ N + + + IQE+ L+ + D+
Sbjct: 1014 LEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDE 1073
Query: 256 FIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS-DL 314
LEE + E S ++++ EN + EI LN+K+ + + + E L++ +
Sbjct: 1074 IKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEK 1133
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+++++ EE+ L + ++ N ++++ +N+ ++ ++ S K+ ++LS L
Sbjct: 1134 DQRISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQS--KLDSELSA-L 1190
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ + + + + I ++ ++ +Q+ D QL+ + + E
Sbjct: 1191 ERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQK-------------LNCE 1237
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
+ ++T KE +E + V E +L++ S+ + +++ K+ E
Sbjct: 1238 KDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQE 1297
Query: 495 WKSQF-EDLDDVMKQQQKELK 514
K++F E L++ K++ +E++
Sbjct: 1298 EKAKFLEQLEEQEKRKNEEMQ 1318
>BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 56.8 bits (131), Expect = 2e-07
Identities = 99/526 (18%), Positives = 205/526 (38%), Gaps = 29/526 (5%)
Query: 7 TLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQL 66
T+F E I A K + E K++ +LK + G + + L ++ N
Sbjct: 801 TVFVPPEKHEKEIIALKSNIVELKKQLSELK----KKCGEDQEKIHALTSENTNLKKMMS 856
Query: 67 XXXXXXXXXXXXXLTEKLTIAETKHN--DLKKLYEDSASELEALKRENI----QMHTSDV 120
+T T+A+T D+KK +ED E +K +N + +
Sbjct: 857 NQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQN 916
Query: 121 MVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETD 179
+ E I SL E +++ +S+ +V + K I TL ++ K E D
Sbjct: 917 QIKAEYI-SLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELD 975
Query: 180 INELRNSIKY-----LESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
+ +KY E + ++ ++L +QL+ K + +EEV K EN L +
Sbjct: 976 TIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKK 1035
Query: 235 XXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEK---DENFKQEIDMLNE 291
+ L KT + ++L ++ +K +N K+++ N
Sbjct: 1036 EIFTLQKDLRDKTVLIEKSHEMERALSR-KTDELNKQLKDLSQKYTEVKNVKEKLVEENA 1094
Query: 292 KLICDRREFNETMQEKNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
K + +Q++++ L L K +N T L+E+ + + E+ T ++
Sbjct: 1095 KQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQ 1154
Query: 349 LIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQK 408
L+EN N +A +I E+ + E+ + +K+ ++ L +++ T++
Sbjct: 1155 LLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKM-EEVSKLQSEVQNTKQ 1213
Query: 409 NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
L +++ DL++ + +Q+ + N++L + EEV K
Sbjct: 1214 ----ALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ EI+D K + + + +L +++ K+++
Sbjct: 1270 SAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIE 1315
Score = 48.4 bits (110), Expect = 6e-05
Identities = 50/247 (20%), Positives = 104/247 (42%), Gaps = 7/247 (2%)
Query: 274 EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER---ELEEKQE 330
E+ + E ++L ++L R Q++ L ++L+ KV + + E E +E
Sbjct: 427 ELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKE 486
Query: 331 QLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYERISLTL 389
++QL D + K + KV Q+ + F + L+ E + E + L
Sbjct: 487 DSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQL 546
Query: 390 DKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
+ + ++ + Q N ++ E K+ L E+N L++ LS E E ++
Sbjct: 547 KDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKG 606
Query: 448 IEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMK 507
++ + G +E++ L S SNE+ + K++E + + E ++
Sbjct: 607 RKVTEMEGQAKELSAKLA-LSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIR 665
Query: 508 QQQKELK 514
Q ++EL+
Sbjct: 666 QLKRELE 672
Score = 47.2 bits (107), Expect = 1e-04
Identities = 95/456 (20%), Positives = 191/456 (41%), Gaps = 42/456 (9%)
Query: 93 DLKKLYEDSASELEALKRE--NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++++ +E S SE+ LKRE N++ + V PE + +V + L L + E
Sbjct: 652 EMEREHEKSLSEIRQLKRELENVKAKLAQ-HVKPEEHE---QVKSRLEQKSGELGKKITE 707
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDIN-ELRNS---IKYLESVKSEYNTANEKLFE 206
+ LK ++ K+ I L +KL+ + ++ E++N +K E +K ++ + L
Sbjct: 708 LTLKNQTLQKE-IEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNR 766
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+L + K + E++ L +EN +L + +N+ E+K
Sbjct: 767 KLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQ 826
Query: 267 LVE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L E +K E +EK E L +K++ ++ +T +E + L+D K N+ +
Sbjct: 827 LSELKKKCGEDQEKIHALTSENTNL-KKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLD 885
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----QIASDFKISNQLSCELDDESEN 380
+++K E + ++ D + +EN N++ +A + LS + ++
Sbjct: 886 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 945
Query: 381 TYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAK------------------KQ 421
E I K I L+ +I +K D Q + K K+
Sbjct: 946 NAE-ILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKE 1004
Query: 422 IAD-LTEQN---IILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
+ D L+EQ + +E + + + EN +L EI T++ + T+ ++ S
Sbjct: 1005 LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK 1064
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
+ +++D+ K E K+ E L + +Q E+
Sbjct: 1065 TDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEI 1100
Score = 41.9 bits (94), Expect = 0.005
Identities = 48/244 (19%), Positives = 102/244 (41%), Gaps = 9/244 (3%)
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---LSKKVNKTERE 324
++++L ++K K E E+ L ++ + E +++ L+ + L K+++ E E
Sbjct: 542 LKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEME 601
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLI--ENMFNKVSQIASDFKISNQLSCELDDESENTY 382
E+K ++T + Q + I E N S ++++ + E++ E E +
Sbjct: 602 REKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSL 661
Query: 383 ERISLTLDKITNHITYLNTQI----NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
I ++ N L + +E K+ Q E K+I +LT +N L++ + +
Sbjct: 662 SEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEK 721
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
+ +NK L + + + + LK S + ++ D+ K E K +
Sbjct: 722 VYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLE 781
Query: 499 FEDL 502
E L
Sbjct: 782 MEKL 785
>BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with
coiled-coil domains and ankyrin repeats protein.
Length = 1416
Score = 56.8 bits (131), Expect = 2e-07
Identities = 99/526 (18%), Positives = 205/526 (38%), Gaps = 29/526 (5%)
Query: 7 TLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQL 66
T+F E I A K + E K++ +LK + G + + L ++ N
Sbjct: 801 TVFVPPEKHEKEIIALKSNIVELKKQLSELK----KKCGEDQEKIHALTSENTNLKKMMS 856
Query: 67 XXXXXXXXXXXXXLTEKLTIAETKHN--DLKKLYEDSASELEALKRENI----QMHTSDV 120
+T T+A+T D+KK +ED E +K +N + +
Sbjct: 857 NQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQN 916
Query: 121 MVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETD 179
+ E I SL E +++ +S+ +V + K I TL ++ K E D
Sbjct: 917 QIKAEYI-SLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELD 975
Query: 180 INELRNSIKY-----LESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
+ +KY E + ++ ++L +QL+ K + +EEV K EN L +
Sbjct: 976 TIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKK 1035
Query: 235 XXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEK---DENFKQEIDMLNE 291
+ L KT + ++L ++ +K +N K+++ N
Sbjct: 1036 EIFTLQKDLRDKTVLIEKSHEMERALSR-KTDELNKQLKDLSQKYTEVKNVKEKLVEENA 1094
Query: 292 KLICDRREFNETMQEKNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
K + +Q++++ L L K +N T L+E+ + + E+ T ++
Sbjct: 1095 KQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQ 1154
Query: 349 LIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQK 408
L+EN N +A +I E+ + E+ + +K+ ++ L +++ T++
Sbjct: 1155 LLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKM-EEVSKLQSEVQNTKQ 1213
Query: 409 NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
L +++ DL++ + +Q+ + N++L + EEV K
Sbjct: 1214 ----ALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ EI+D K + + + +L +++ K+++
Sbjct: 1270 SAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIE 1315
Score = 48.4 bits (110), Expect = 6e-05
Identities = 50/247 (20%), Positives = 104/247 (42%), Gaps = 7/247 (2%)
Query: 274 EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER---ELEEKQE 330
E+ + E ++L ++L R Q++ L ++L+ KV + + E E +E
Sbjct: 427 ELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKE 486
Query: 331 QLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYERISLTL 389
++QL D + K + KV Q+ + F + L+ E + E + L
Sbjct: 487 DSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQL 546
Query: 390 DKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
+ + ++ + Q N ++ E K+ L E+N L++ LS E E ++
Sbjct: 547 KDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKG 606
Query: 448 IEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMK 507
++ + G +E++ L S SNE+ + K++E + + E ++
Sbjct: 607 RKVTEMEGQAKELSAKLA-LSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIR 665
Query: 508 QQQKELK 514
Q ++EL+
Sbjct: 666 QLKRELE 672
Score = 47.2 bits (107), Expect = 1e-04
Identities = 95/456 (20%), Positives = 191/456 (41%), Gaps = 42/456 (9%)
Query: 93 DLKKLYEDSASELEALKRE--NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++++ +E S SE+ LKRE N++ + V PE + +V + L L + E
Sbjct: 652 EMEREHEKSLSEIRQLKRELENVKAKLAQ-HVKPEEHE---QVKSRLEQKSGELGKKITE 707
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDIN-ELRNS---IKYLESVKSEYNTANEKLFE 206
+ LK ++ K+ I L +KL+ + ++ E++N +K E +K ++ + L
Sbjct: 708 LTLKNQTLQKE-IEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNR 766
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+L + K + E++ L +EN +L + +N+ E+K
Sbjct: 767 KLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQ 826
Query: 267 LVE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L E +K E +EK E L +K++ ++ +T +E + L+D K N+ +
Sbjct: 827 LSELKKKCGEDQEKIHALTSENTNL-KKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLD 885
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----QIASDFKISNQLSCELDDESEN 380
+++K E + ++ D + +EN N++ +A + LS + ++
Sbjct: 886 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 945
Query: 381 TYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAK------------------KQ 421
E I K I L+ +I +K D Q + K K+
Sbjct: 946 NAE-ILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKE 1004
Query: 422 IAD-LTEQN---IILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
+ D L+EQ + +E + + + EN +L EI T++ + T+ ++ S
Sbjct: 1005 LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK 1064
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
+ +++D+ K E K+ E L + +Q E+
Sbjct: 1065 TDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEI 1100
Score = 41.9 bits (94), Expect = 0.005
Identities = 48/244 (19%), Positives = 102/244 (41%), Gaps = 9/244 (3%)
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---LSKKVNKTERE 324
++++L ++K K E E+ L ++ + E +++ L+ + L K+++ E E
Sbjct: 542 LKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEME 601
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLI--ENMFNKVSQIASDFKISNQLSCELDDESENTY 382
E+K ++T + Q + I E N S ++++ + E++ E E +
Sbjct: 602 REKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSL 661
Query: 383 ERISLTLDKITNHITYLNTQI----NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
I ++ N L + +E K+ Q E K+I +LT +N L++ + +
Sbjct: 662 SEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEK 721
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
+ +NK L + + + + LK S + ++ D+ K E K +
Sbjct: 722 VYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLE 781
Query: 499 FEDL 502
E L
Sbjct: 782 MEKL 785
>AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein.
Length = 1416
Score = 56.8 bits (131), Expect = 2e-07
Identities = 99/526 (18%), Positives = 205/526 (38%), Gaps = 29/526 (5%)
Query: 7 TLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQL 66
T+F E I A K + E K++ +LK + G + + L ++ N
Sbjct: 801 TVFVPPEKHEKEIIALKSNIVELKKQLSELK----KKCGEDQEKIHALTSENTNLKKMMS 856
Query: 67 XXXXXXXXXXXXXLTEKLTIAETKHN--DLKKLYEDSASELEALKRENI----QMHTSDV 120
+T T+A+T D+KK +ED E +K +N + +
Sbjct: 857 NQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQN 916
Query: 121 MVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETD 179
+ E I SL E +++ +S+ +V + K I TL ++ K E D
Sbjct: 917 QIKAEYI-SLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELD 975
Query: 180 INELRNSIKY-----LESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
+ +KY E + ++ ++L +QL+ K + +EEV K EN L +
Sbjct: 976 TIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKK 1035
Query: 235 XXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEK---DENFKQEIDMLNE 291
+ L KT + ++L ++ +K +N K+++ N
Sbjct: 1036 EIFTLQKDLRDKTVLIEKSHEMERALSR-KTDELNKQLKDLSQKYTEVKNVKEKLVEENA 1094
Query: 292 KLICDRREFNETMQEKNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
K + +Q++++ L L K +N T L+E+ + + E+ T ++
Sbjct: 1095 KQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQ 1154
Query: 349 LIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQK 408
L+EN N +A +I E+ + E+ + +K+ ++ L +++ T++
Sbjct: 1155 LLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKM-EEVSKLQSEVQNTKQ 1213
Query: 409 NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
L +++ DL++ + +Q+ + N++L + EEV K
Sbjct: 1214 ----ALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ EI+D K + + + +L +++ K+++
Sbjct: 1270 SAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIE 1315
Score = 48.4 bits (110), Expect = 6e-05
Identities = 50/247 (20%), Positives = 104/247 (42%), Gaps = 7/247 (2%)
Query: 274 EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER---ELEEKQE 330
E+ + E ++L ++L R Q++ L ++L+ KV + + E E +E
Sbjct: 427 ELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKE 486
Query: 331 QLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYERISLTL 389
++QL D + K + KV Q+ + F + L+ E + E + L
Sbjct: 487 DSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQL 546
Query: 390 DKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
+ + ++ + Q N ++ E K+ L E+N L++ LS E E ++
Sbjct: 547 KDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKG 606
Query: 448 IEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMK 507
++ + G +E++ L S SNE+ + K++E + + E ++
Sbjct: 607 RKVTEMEGQAKELSAKLA-LSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIR 665
Query: 508 QQQKELK 514
Q ++EL+
Sbjct: 666 QLKRELE 672
Score = 47.2 bits (107), Expect = 1e-04
Identities = 95/456 (20%), Positives = 191/456 (41%), Gaps = 42/456 (9%)
Query: 93 DLKKLYEDSASELEALKRE--NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++++ +E S SE+ LKRE N++ + V PE + +V + L L + E
Sbjct: 652 EMEREHEKSLSEIRQLKRELENVKAKLAQ-HVKPEEHE---QVKSRLEQKSGELGKKITE 707
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDIN-ELRNS---IKYLESVKSEYNTANEKLFE 206
+ LK ++ K+ I L +KL+ + ++ E++N +K E +K ++ + L
Sbjct: 708 LTLKNQTLQKE-IEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNR 766
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+L + K + E++ L +EN +L + +N+ E+K
Sbjct: 767 KLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQ 826
Query: 267 LVE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L E +K E +EK E L +K++ ++ +T +E + L+D K N+ +
Sbjct: 827 LSELKKKCGEDQEKIHALTSENTNL-KKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLD 885
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----QIASDFKISNQLSCELDDESEN 380
+++K E + ++ D + +EN N++ +A + LS + ++
Sbjct: 886 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 945
Query: 381 TYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAK------------------KQ 421
E I K I L+ +I +K D Q + K K+
Sbjct: 946 NAE-ILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKE 1004
Query: 422 IAD-LTEQN---IILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
+ D L+EQ + +E + + + EN +L EI T++ + T+ ++ S
Sbjct: 1005 LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK 1064
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
+ +++D+ K E K+ E L + +Q E+
Sbjct: 1065 TDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEI 1100
Score = 41.9 bits (94), Expect = 0.005
Identities = 48/244 (19%), Positives = 102/244 (41%), Gaps = 9/244 (3%)
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---LSKKVNKTERE 324
++++L ++K K E E+ L ++ + E +++ L+ + L K+++ E E
Sbjct: 542 LKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEME 601
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLI--ENMFNKVSQIASDFKISNQLSCELDDESENTY 382
E+K ++T + Q + I E N S ++++ + E++ E E +
Sbjct: 602 REKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSL 661
Query: 383 ERISLTLDKITNHITYLNTQI----NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
I ++ N L + +E K+ Q E K+I +LT +N L++ + +
Sbjct: 662 SEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEK 721
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
+ +NK L + + + + LK S + ++ D+ K E K +
Sbjct: 722 VYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLE 781
Query: 499 FEDL 502
E L
Sbjct: 782 MEKL 785
>AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein.
Length = 1416
Score = 56.8 bits (131), Expect = 2e-07
Identities = 99/526 (18%), Positives = 205/526 (38%), Gaps = 29/526 (5%)
Query: 7 TLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQL 66
T+F E I A K + E K++ +LK + G + + L ++ N
Sbjct: 801 TVFVPPEKHEKEIIALKSNIVELKKQLSELK----KKCGEDQEKIHALTSENTNLKKMMS 856
Query: 67 XXXXXXXXXXXXXLTEKLTIAETKHN--DLKKLYEDSASELEALKRENI----QMHTSDV 120
+T T+A+T D+KK +ED E +K +N + +
Sbjct: 857 NQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQN 916
Query: 121 MVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETD 179
+ E I SL E +++ +S+ +V + K I TL ++ K E D
Sbjct: 917 QIKAEYI-SLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELD 975
Query: 180 INELRNSIKY-----LESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
+ +KY E + ++ ++L +QL+ K + +EEV K EN L +
Sbjct: 976 TIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKK 1035
Query: 235 XXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEK---DENFKQEIDMLNE 291
+ L KT + ++L ++ +K +N K+++ N
Sbjct: 1036 EIFTLQKDLRDKTVLIEKSHEMERALSR-KTDELNKQLKDLSQKYTEVKNVKEKLVEENA 1094
Query: 292 KLICDRREFNETMQEKNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
K + +Q++++ L L K +N T L+E+ + + E+ T ++
Sbjct: 1095 KQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQ 1154
Query: 349 LIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQK 408
L+EN N +A +I E+ + E+ + +K+ ++ L +++ T++
Sbjct: 1155 LLENQKNSSVPLAEHLQIKEAFEKEVGIIKASLREKEEESQNKM-EEVSKLQSEVQNTKQ 1213
Query: 409 NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
L +++ DL++ + +Q+ + N++L + EEV K
Sbjct: 1214 ----ALKKLETREVVDLSKYKATKSDLETQISSLNEKLANLNRKYEEVCEEVLHAKKKEI 1269
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ EI+D K + + + +L +++ K+++
Sbjct: 1270 SAKDEKELLHFSIEQEIKDQKERCDKSLTTITELQRRIQESAKQIE 1315
Score = 48.4 bits (110), Expect = 6e-05
Identities = 50/247 (20%), Positives = 104/247 (42%), Gaps = 7/247 (2%)
Query: 274 EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER---ELEEKQE 330
E+ + E ++L ++L R Q++ L ++L+ KV + + E E +E
Sbjct: 427 ELSLPSQTSYSENEILKKELEAMRTFCESAKQDRLKLQNELAHKVAECKALALECERVKE 486
Query: 331 QLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYERISLTL 389
++QL D + K + KV Q+ + F + L+ E + E + L
Sbjct: 487 DSDEQIKQLEDALKDVQKRMYESEGKVKQMQTHFLALKEHLTSEAASGNHRLTEELKDQL 546
Query: 390 DKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
+ + ++ + Q N ++ E K+ L E+N L++ LS E E ++
Sbjct: 547 KDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEMEREKKG 606
Query: 448 IEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMK 507
++ + G +E++ L S SNE+ + K++E + + E ++
Sbjct: 607 RKVTEMEGQAKELSAKLA-LSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSLSEIR 665
Query: 508 QQQKELK 514
Q ++EL+
Sbjct: 666 QLKRELE 672
Score = 47.2 bits (107), Expect = 1e-04
Identities = 95/456 (20%), Positives = 191/456 (41%), Gaps = 42/456 (9%)
Query: 93 DLKKLYEDSASELEALKRE--NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++++ +E S SE+ LKRE N++ + V PE + +V + L L + E
Sbjct: 652 EMEREHEKSLSEIRQLKRELENVKAKLAQ-HVKPEEHE---QVKSRLEQKSGELGKKITE 707
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDIN-ELRNS---IKYLESVKSEYNTANEKLFE 206
+ LK ++ K+ I L +KL+ + ++ E++N +K E +K ++ + L
Sbjct: 708 LTLKNQTLQKE-IEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNR 766
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+L + K + E++ L +EN +L + +N+ E+K
Sbjct: 767 KLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQ 826
Query: 267 LVE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L E +K E +EK E L +K++ ++ +T +E + L+D K N+ +
Sbjct: 827 LSELKKKCGEDQEKIHALTSENTNL-KKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLD 885
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----QIASDFKISNQLSCELDDESEN 380
+++K E + ++ D + +EN N++ +A + LS + ++
Sbjct: 886 VKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDS 945
Query: 381 TYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAK------------------KQ 421
E I K I L+ +I +K D Q + K K+
Sbjct: 946 NAE-ILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKE 1004
Query: 422 IAD-LTEQN---IILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
+ D L+EQ + +E + + + EN +L EI T++ + T+ ++ S
Sbjct: 1005 LKDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRK 1064
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
+ +++D+ K E K+ E L + +Q E+
Sbjct: 1065 TDELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEI 1100
Score = 41.9 bits (94), Expect = 0.005
Identities = 48/244 (19%), Positives = 102/244 (41%), Gaps = 9/244 (3%)
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---LSKKVNKTERE 324
++++L ++K K E E+ L ++ + E +++ L+ + L K+++ E E
Sbjct: 542 LKDQLKDLKVKYEGASAEVGKLRNQIKQNEMIVEEFKRDEGKLIEENKRLQKELSMCEME 601
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLI--ENMFNKVSQIASDFKISNQLSCELDDESENTY 382
E+K ++T + Q + I E N S ++++ + E++ E E +
Sbjct: 602 REKKGRKVTEMEGQAKELSAKLALSIPAEKFENMKSSLSNEVNEKAKKLVEMEREHEKSL 661
Query: 383 ERISLTLDKITNHITYLNTQI----NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
I ++ N L + +E K+ Q E K+I +LT +N L++ + +
Sbjct: 662 SEIRQLKRELENVKAKLAQHVKPEEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEK 721
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
+ +NK L + + + + LK S + ++ D+ K E K +
Sbjct: 722 VYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLE 781
Query: 499 FEDL 502
E L
Sbjct: 782 MEKL 785
>BC113524-1|AAI13525.1| 578|Homo sapiens IFT74 protein protein.
Length = 578
Score = 56.4 bits (130), Expect = 2e-07
Identities = 87/376 (23%), Positives = 162/376 (43%), Gaps = 48/376 (12%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
+SL+ + E K+ I I+ +K T + N +KYLE T N
Sbjct: 163 QSLDVIFTERQAKEKQIRSVEEEIEQ--EKQATDDIIKNMSFENQVKYLEM-----KTTN 215
Query: 202 EKLFEQLNNA---VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
EKL ++L+ +D QN +E ++ +I + + Q RD+ IA
Sbjct: 216 EKLLQELDTLQQQLDSQNMKKESLEA-EIAHSQVKQEAVLLHEKLYELESH---RDQMIA 271
Query: 259 NLEEMKTMLVEEKLSEIKE-KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK- 316
+ + + + EE+ +K+ KD+N QEI + +L + + N+ ++E L DL +
Sbjct: 272 EDKSIGSPM-EEREKLLKQIKDDN--QEIASMERQLTDTKEKINQFIEEIRQLDMDLEEH 328
Query: 317 --KVNKTERELEEKQEQLTHLMEQLNDTENNSYK-----------LIENMFNKVSQIASD 363
++N+ +EL++++E + +E +T+N K L+E+ +++I
Sbjct: 329 QGEMNQKYKELKKREEHMDTFIETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQI 388
Query: 364 FKISNQ-LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
I+NQ L DD + + E + K + L + I Q + L E+K
Sbjct: 389 SSITNQELKMMQDDLNFKSTE-----VQKSQSTAQNLTSDIQRLQLDLQKMELLESK--- 440
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS----STXXXXXXXXX 478
+TE+ LK ++ Q+ T+ E+ ++ ++ S EE L ST
Sbjct: 441 --MTEEQHSLKSKIKQMTTD-LEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIM 497
Query: 479 XXXSNEIEDMKTKVME 494
+ E E +KT++ E
Sbjct: 498 EKQNIEYEALKTQLQE 513
>AY040325-1|AAK77221.1| 600|Homo sapiens capillary morphogenesis
protein-1 protein.
Length = 600
Score = 56.4 bits (130), Expect = 2e-07
Identities = 87/376 (23%), Positives = 162/376 (43%), Gaps = 48/376 (12%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
+SL+ + E K+ I I+ +K T + N +KYLE T N
Sbjct: 185 QSLDVIFTERQAKEKQIRSVEEEIEQ--EKQATDDIIKNMSFENQVKYLEM-----KTTN 237
Query: 202 EKLFEQLNNA---VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
EKL ++L+ +D QN +E ++ +I + + Q RD+ IA
Sbjct: 238 EKLLQELDTLQQQLDSQNMKKESLEA-EIAHSQVKQEAVLLHEKLYELESH---RDQMIA 293
Query: 259 NLEEMKTMLVEEKLSEIKE-KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK- 316
+ + + + EE+ +K+ KD+N QEI + +L + + N+ ++E L DL +
Sbjct: 294 EDKSIGSPM-EEREKLLKQIKDDN--QEIASMERQLTDTKEKINQFIEEIRQLDMDLEEH 350
Query: 317 --KVNKTERELEEKQEQLTHLMEQLNDTENNSYK-----------LIENMFNKVSQIASD 363
++N+ +EL++++E + +E +T+N K L+E+ +++I
Sbjct: 351 QGEMNQKYKELKKREEHMDTFIETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQI 410
Query: 364 FKISNQ-LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
I+NQ L DD + + E + K + L + I Q + L E+K
Sbjct: 411 SSITNQELKMMQDDLNFKSTE-----VQKSQSTAQNLTSDIQRLQLDLQKMELLESK--- 462
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS----STXXXXXXXXX 478
+TE+ LK ++ Q+ T+ E+ ++ ++ S EE L ST
Sbjct: 463 --MTEEQHSLKSKIKQMTTD-LEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIM 519
Query: 479 XXXSNEIEDMKTKVME 494
+ E E +KT++ E
Sbjct: 520 EKQNIEYEALKTQLQE 535
>AL356133-4|CAH72643.1| 600|Homo sapiens intraflagellar transport
74 homolog (Chlamydomonas) protein.
Length = 600
Score = 56.4 bits (130), Expect = 2e-07
Identities = 87/376 (23%), Positives = 162/376 (43%), Gaps = 48/376 (12%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
+SL+ + E K+ I I+ +K T + N +KYLE T N
Sbjct: 185 QSLDVIFTERQAKEKQIRSVEEEIEQ--EKQATDDIIKNMSFENQVKYLEM-----KTTN 237
Query: 202 EKLFEQLNNA---VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
EKL ++L+ +D QN +E ++ +I + + Q RD+ IA
Sbjct: 238 EKLLQELDTLQQQLDSQNMKKESLEA-EIAHSQVKQEAVLLHEKLYELESH---RDQMIA 293
Query: 259 NLEEMKTMLVEEKLSEIKE-KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK- 316
+ + + + EE+ +K+ KD+N QEI + +L + + N+ ++E L DL +
Sbjct: 294 EDKSIGSPM-EEREKLLKQIKDDN--QEIASMERQLTDTKEKINQFIEEIRQLDMDLEEH 350
Query: 317 --KVNKTERELEEKQEQLTHLMEQLNDTENNSYK-----------LIENMFNKVSQIASD 363
++N+ +EL++++E + +E +T+N K L+E+ +++I
Sbjct: 351 QGEMNQKYKELKKREEHMDTFIETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQI 410
Query: 364 FKISNQ-LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
I+NQ L DD + + E + K + L + I Q + L E+K
Sbjct: 411 SSITNQELKMMQDDLNFKSTE-----VQKSQSTAQNLTSDIQRLQLDLQKMELLESK--- 462
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS----STXXXXXXXXX 478
+TE+ LK ++ Q+ T+ E+ ++ ++ S EE L ST
Sbjct: 463 --MTEEQHSLKSKIKQMTTD-LEIYNDLPALKSSGEEKIKKLHQERMILSTHRNAFKKIM 519
Query: 479 XXXSNEIEDMKTKVME 494
+ E E +KT++ E
Sbjct: 520 EKQNIEYEALKTQLQE 535
>Z20656-1|CAA79675.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 56.0 bits (129), Expect = 3e-07
Identities = 84/420 (20%), Positives = 174/420 (41%), Gaps = 22/420 (5%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLT 85
L E Y+E + K+ LQ+ + + VA+ + I++ L ++L
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR----TEELEEAKKKLAQRLQ 1400
Query: 86 IAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL- 144
AE + + S LE K +Q D+MV E ++ ++ F+ +
Sbjct: 1401 DAE----EAVEAVNAKCSSLEKTKHR-LQNEIEDLMVDVERSNAAAAALDKKQRNFDKIL 1455
Query: 145 ---EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++ E + S K+ S+ T L KL E + L + ++++ E +
Sbjct: 1456 AEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLT 1515
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L E N + + +++++++ K+E Q+ L+ A+ +F
Sbjct: 1516 EQLGEGGKNVHELEK-VRKQLEVEKLELQSALEEAEASLEHEEGKILR--AQLEFNQIKA 1572
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK---KV 318
E++ L E K E+++ N ++ +D L L + R NE ++ K + DL++ ++
Sbjct: 1573 EIERKLAE-KDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQL 1631
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ R E Q+Q+ L L DT+ + + IA + +N L EL +E
Sbjct: 1632 SHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL-EEL 1690
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
E+ + + + ++ + + N L+ + KK +DLT+ ++E + +
Sbjct: 1691 RAVVEQTERSRKLAEQELIETSERV-QLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQE 1749
Score = 45.2 bits (102), Expect = 6e-04
Identities = 69/335 (20%), Positives = 138/335 (41%), Gaps = 23/335 (6%)
Query: 134 INTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYL 190
+ + E EE+ E+ KK + + +K +D L + K E + + N +K L
Sbjct: 921 VKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 980
Query: 191 ESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXX 248
+ + KL ++ A+ Q Q+ +D L++E N L
Sbjct: 981 TEEMAGLDEIIAKLTKE-KKAL--QEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLE 1037
Query: 249 XXXARDKFIA-NLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQ 305
++K + +LE K L + KL++ D EN K +++ +K D + N ++
Sbjct: 1038 GSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIE 1097
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
++ L L KK+ + + +EE +E+L E L + ++S+ +
Sbjct: 1098 DEQALALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSREL-EEISERLEEAG 1156
Query: 366 ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL 425
+ + E++ + E ++++ L++ T Q T A L + +A+L
Sbjct: 1157 GATSVQIEMNKKREAEFQKMRRDLEEAT-------LQHEATA----AALRKKHADSVAEL 1205
Query: 426 TEQNIILKERLSQLETENKELLIEIQTVRGSNEEV 460
EQ L+ +LE E E +E+ V + E++
Sbjct: 1206 GEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1240
Score = 43.2 bits (97), Expect = 0.002
Identities = 89/472 (18%), Positives = 179/472 (37%), Gaps = 43/472 (9%)
Query: 82 EKLTIAETKHNDLKKL---YEDSASELE-ALKREN-IQMHTSDVMVVPEIIDSLT-EVIN 135
+ L + E K N L K E +LE +L++E ++M E LT E I
Sbjct: 1010 DDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1069
Query: 136 TLTNGFESLEEVAL--EIDL-KKNSITKDNISIKTLLDKLITKNETDINELRNSIKY--- 189
L N LEE E D+ ++NS +D ++ L K + +N+ I EL ++
Sbjct: 1070 DLENDKLQLEEKLKKKEFDINQQNSKIEDEQALALQLQKKLKENQARIEELEEELEAERT 1129
Query: 190 ----LESVKSEYNTANEKLFEQLNNA-----VDKQNCIQEEVDLLKIEN---QNLLQXXX 237
+E ++S+ + E++ E+L A V + + E + K+ + LQ
Sbjct: 1130 ARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEA 1189
Query: 238 XXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLS---EIKEKDENFKQ------EIDM 288
+ I NL+ +K L +EK E+ + N +Q ++
Sbjct: 1190 TAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEK 1249
Query: 289 LNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
++ L E+ ++E L+D + + K + E E QL ++
Sbjct: 1250 VSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLS 1309
Query: 349 LIENMFNKVSQIASDFKISNQLSCELD------DESENTYERISLTLDKITNHITYLNTQ 402
+ M + Q+ + K N L+ L D YE + ++ ++ N++
Sbjct: 1310 YTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSE 1369
Query: 403 INETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL 462
+ + + +A ++ +L E L +RL E + + + ++ + +
Sbjct: 1370 VAQWRTKYET----DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425
Query: 463 NLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
++D + + + EWK ++E+ ++ QKE +
Sbjct: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1477
Score = 37.5 bits (83), Expect = 0.11
Identities = 42/216 (19%), Positives = 96/216 (44%), Gaps = 17/216 (7%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
ET+++ +L +K+ +E + Q Q+ + LND E +LI+ NK+ A
Sbjct: 863 ETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIK---NKIQLEA 919
Query: 362 SDFKISNQLSCELDDESENTYERISL--TLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
+++ +L E + +E T ++ L ++ I L + + +K +A +
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA-----TE 974
Query: 420 KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXX 479
++ +LTE+ L E +++L E K L + ++++ +L+
Sbjct: 975 NKVKNLTEEMAGLDEIIAKLTKEKKAL-------QEAHQQALDDLQVEEDKVNSLSKSKV 1027
Query: 480 XXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 1028 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1063
>D00943-1|BAA00791.1| 1939|Homo sapiens cardiac alpha-myosin heavy
chain protein.
Length = 1939
Score = 56.0 bits (129), Expect = 3e-07
Identities = 85/420 (20%), Positives = 175/420 (41%), Gaps = 22/420 (5%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLT 85
L E Y+E + K+ LQ+ + + VA+ + I++ L ++L
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQCRTKYETDAIQR----TEELEEAKKKLAQRLQ 1400
Query: 86 IAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL- 144
AE + + S LE K +Q D+MV E ++ ++ F+ +
Sbjct: 1401 DAE----EAVEAVNAKCSSLEKTKHR-LQNEIEDLMVDVERSNAAAAALDKKQRNFDKIL 1455
Query: 145 ---EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++ E + S K+ S+ T L KL E + L + ++++ E +
Sbjct: 1456 AEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLT 1515
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L E N + + +++++++ K+E Q+ L+ A+ +F
Sbjct: 1516 EQLGEGGKNVHELEK-VRKQLEVEKLELQSALEEAEASLEHEEGKILR--AQLEFNQIKA 1572
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK---KV 318
E++ L E K E+++ N ++ +D L L + R NE ++ K + DL++ ++
Sbjct: 1573 EIERKLAE-KDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQL 1631
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ R E Q+Q+ L L DT+ + + IA + +N L EL +E
Sbjct: 1632 SHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL-EEL 1690
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
E+ + K+ + ++ + + N L+ + KK ADL++ ++E + +
Sbjct: 1691 RAVVEQTERS-RKLADRELIETSERVQLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQE 1749
Score = 45.6 bits (103), Expect = 4e-04
Identities = 69/335 (20%), Positives = 138/335 (41%), Gaps = 23/335 (6%)
Query: 134 INTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYL 190
+ + E EE+ E+ KK + + +K +D L + K E + + N +K L
Sbjct: 921 VKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 980
Query: 191 ESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXX 248
+ + KL ++ A+ Q Q+ +D L+ E N L
Sbjct: 981 TEEMAGLDEIIAKLTKE-KKAL--QEAHQQALDDLQAEEDKVNTLSKSKVKLEQQVDDLE 1037
Query: 249 XXXARDKFIA-NLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQ 305
++K + +LE K L + KL++ D EN K +++ +K D + N ++
Sbjct: 1038 GSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIE 1097
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
++ +L L KK+ + + +EE +E+L E L + ++S+ +
Sbjct: 1098 DEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSREL-EEISERLEEAG 1156
Query: 366 ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL 425
+ + E++ + E ++++ L++ T Q T A L + +A+L
Sbjct: 1157 GATSVQIEMNKKREAEFQKMRRDLEEAT-------LQHEATA----AALRKKHADSVAEL 1205
Query: 426 TEQNIILKERLSQLETENKELLIEIQTVRGSNEEV 460
EQ L+ +LE E E +E+ V + E++
Sbjct: 1206 GEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1240
Score = 42.7 bits (96), Expect = 0.003
Identities = 83/464 (17%), Positives = 178/464 (38%), Gaps = 41/464 (8%)
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLT-EVINTLTNGFES 143
T++++K L++ +D LE K+ + + + + ++ LT E I L N
Sbjct: 1021 TLSKSKVK-LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL--KLTQESIMDLENDKLQ 1077
Query: 144 LEEVAL--EIDL-KKNSITKDNISIKTLLDKLITKNETDINELRNSIKY-------LESV 193
LEE E D+ ++NS +D + L K + +N+ I EL ++ +E +
Sbjct: 1078 LEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKL 1137
Query: 194 KSEYNTANEKLFEQLNNA-----VDKQNCIQEEVDLLKIEN---QNLLQXXXXXXXXXXX 245
+S+ + E++ E+L A V + + E + K+ + LQ
Sbjct: 1138 RSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRKK 1197
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLS---EIKEKDENFKQ------EIDMLNEKLICD 296
+ I NL+ +K L +EK E+ + N +Q ++ ++ L
Sbjct: 1198 HADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSRTLEDQ 1257
Query: 297 RREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK 356
E+ ++E L+D + + K + E E QL ++ + M +
Sbjct: 1258 ANEYRVKLEEAQRSLNDFTTQRAKLQTENGELSRQLEEKEALISQLTRGKLSYTQQMEDL 1317
Query: 357 VSQIASDFKISNQLSCELD------DESENTYERISLTLDKITNHITYLNTQINETQKND 410
Q+ + K N L+ L D YE + ++ ++ N+++ + +
Sbjct: 1318 KRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQCRTKY 1377
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTX 470
+A ++ +L E L +RL E + + + ++ + + ++D
Sbjct: 1378 ET----DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVD 1433
Query: 471 XXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ + + EWK ++E+ ++ QKE +
Sbjct: 1434 VERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1477
Score = 37.9 bits (84), Expect = 0.085
Identities = 42/216 (19%), Positives = 96/216 (44%), Gaps = 17/216 (7%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
ET+++ +L +K+ +E + Q Q+ + LND E +LI+ NK+ A
Sbjct: 863 ETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIK---NKIQLEA 919
Query: 362 SDFKISNQLSCELDDESENTYERISL--TLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
+++ +L E + +E T ++ L ++ I L + + +K +A +
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA-----TE 974
Query: 420 KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXX 479
++ +LTE+ L E +++L E K L + ++++ +L+
Sbjct: 975 NKVKNLTEEMAGLDEIIAKLTKEKKAL-------QEAHQQALDDLQAEEDKVNTLSKSKV 1027
Query: 480 XXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 1028 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1063
>BC132667-1|AAI32668.1| 1939|Homo sapiens myosin, heavy chain 6,
cardiac muscle, alpha (cardiomyopathy, hypertrophic 1)
protein.
Length = 1939
Score = 56.0 bits (129), Expect = 3e-07
Identities = 84/420 (20%), Positives = 174/420 (41%), Gaps = 22/420 (5%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLT 85
L E Y+E + K+ LQ+ + + VA+ + I++ L ++L
Sbjct: 1345 LREQYEEETEAKAELQRVLSKANSEVAQWRTKYETDAIQR----TEELEEAKKKLAQRLQ 1400
Query: 86 IAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL- 144
AE + + S LE K +Q D+MV E ++ ++ F+ +
Sbjct: 1401 DAE----EAVEAVNAKCSSLEKTKHR-LQNEIEDLMVDVERSNAAAAALDKKQRNFDKIL 1455
Query: 145 ---EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++ E + S K+ S+ T L KL E + L + ++++ E +
Sbjct: 1456 AEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLT 1515
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L E N + + +++++++ K+E Q+ L+ A+ +F
Sbjct: 1516 EQLGEGGKNVHELEK-VRKQLEVEKLELQSALEEAEASLEHEEGKILR--AQLEFNQIKA 1572
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK---KV 318
E++ L E K E+++ N ++ +D L L + R NE ++ K + DL++ ++
Sbjct: 1573 EIERKLAE-KDEEMEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQL 1631
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ R E Q+Q+ L L DT+ + + IA + +N L EL +E
Sbjct: 1632 SHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL-EEL 1690
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
E+ + + + ++ + + N L+ + KK +DLT+ ++E + +
Sbjct: 1691 RAVVEQTERSRKLAEQELIETSERV-QLLHSQNTSLINQKKKMESDLTQLQSEVEEAVQE 1749
Score = 46.8 bits (106), Expect = 2e-04
Identities = 69/335 (20%), Positives = 139/335 (41%), Gaps = 23/335 (6%)
Query: 134 INTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYL 190
+ + E EE+ E+ KK + + +K +D L + K E + + N +K L
Sbjct: 921 VKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 980
Query: 191 ESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXX 248
+ + KL ++ A+ Q Q+ +D L++E N L
Sbjct: 981 TEEMAGLDEIIAKLTKE-KKAL--QEAHQQALDDLQVEEDKVNSLSKSKVKLEQQVDDLE 1037
Query: 249 XXXARDKFIA-NLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQ 305
++K + +LE K L + KL++ D EN K +++ +K D + N ++
Sbjct: 1038 GSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDKLQLEEKLKKKEFDINQQNSKIE 1097
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
++ +L L KK+ + + +EE +E+L E L + ++S+ +
Sbjct: 1098 DEQVLALQLQKKLKENQARIEELEEELEAERTARAKVEKLRSDLSREL-EEISERLEEAG 1156
Query: 366 ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL 425
+ + E++ + E ++++ L++ T Q T A L + +A+L
Sbjct: 1157 GATSVQIEMNKKREAEFQKMRRDLEEAT-------LQHEATA----AALRKKHADSVAEL 1205
Query: 426 TEQNIILKERLSQLETENKELLIEIQTVRGSNEEV 460
EQ L+ +LE E E +E+ V + E++
Sbjct: 1206 GEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQI 1240
Score = 41.9 bits (94), Expect = 0.005
Identities = 89/472 (18%), Positives = 178/472 (37%), Gaps = 43/472 (9%)
Query: 82 EKLTIAETKHNDLKKL---YEDSASELE-ALKREN-IQMHTSDVMVVPEIIDSLT-EVIN 135
+ L + E K N L K E +LE +L++E ++M E LT E I
Sbjct: 1010 DDLQVEEDKVNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM 1069
Query: 136 TLTNGFESLEEVAL--EIDL-KKNSITKDNISIKTLLDKLITKNETDINELRNSIKY--- 189
L N LEE E D+ ++NS +D + L K + +N+ I EL ++
Sbjct: 1070 DLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAERT 1129
Query: 190 ----LESVKSEYNTANEKLFEQLNNA-----VDKQNCIQEEVDLLKIEN---QNLLQXXX 237
+E ++S+ + E++ E+L A V + + E + K+ + LQ
Sbjct: 1130 ARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEA 1189
Query: 238 XXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLS---EIKEKDENFKQ------EIDM 288
+ I NL+ +K L +EK E+ + N +Q ++
Sbjct: 1190 TAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEK 1249
Query: 289 LNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
++ L E+ ++E L+D + + K + E E QL ++
Sbjct: 1250 VSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQLEEKEALISQLTRGKLS 1309
Query: 349 LIENMFNKVSQIASDFKISNQLSCELD------DESENTYERISLTLDKITNHITYLNTQ 402
+ M + Q+ + K N L+ L D YE + ++ ++ N++
Sbjct: 1310 YTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSE 1369
Query: 403 INETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL 462
+ + + +A ++ +L E L +RL E + + + ++ + +
Sbjct: 1370 VAQWRTKYET----DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425
Query: 463 NLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
++D + + + EWK ++E+ ++ QKE +
Sbjct: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1477
Score = 37.5 bits (83), Expect = 0.11
Identities = 42/216 (19%), Positives = 96/216 (44%), Gaps = 17/216 (7%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
ET+++ +L +K+ +E + Q Q+ + LND E +LI+ NK+ A
Sbjct: 863 ETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAEERCDQLIK---NKIQLEA 919
Query: 362 SDFKISNQLSCELDDESENTYERISL--TLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
+++ +L E + +E T ++ L ++ I L + + +K +A +
Sbjct: 920 KVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHA-----TE 974
Query: 420 KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXX 479
++ +LTE+ L E +++L E K L + ++++ +L+
Sbjct: 975 NKVKNLTEEMAGLDEIIAKLTKEKKAL-------QEAHQQALDDLQVEEDKVNSLSKSKV 1027
Query: 480 XXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 1028 KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1063
>AL137068-7|CAD20123.1| 1007|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1007
Score = 56.0 bits (129), Expect = 3e-07
Identities = 102/504 (20%), Positives = 218/504 (43%), Gaps = 56/504 (11%)
Query: 23 KIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTE 82
KI+ EE KEI ++ + + K +L +E+ + + + L E
Sbjct: 194 KIKQEEILKEINKIVAAKDSDFQCLSKKKEKL-TEELQKLQKDIEMAERNEDHHLQVLKE 252
Query: 83 KLTIAETKHNDLKKLYEDSASELEALKRENIQM-HTSDVMVVPEIIDSLTEVINTLTNGF 141
+ + K +L+KL S+ + + + Q+ H + + + + S+ + L
Sbjct: 253 SEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ--GSMVQAKADLQ--- 307
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETDINELRNSIKYLESVKSEYNTA 200
E+L E+ K N I + +K+LL++L K E ++ ++ L +K E
Sbjct: 308 EALRLGETEVTEKCNHIRE----VKSLLEELSFQKGELNV-QISERKTQLTLIKQEIEKE 362
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L L + ++ +D+L++EN L D+ ++ L
Sbjct: 363 EENLQVVLRQMSKHKTELKNILDMLQLENHEL--------------QGLKLQHDQRVSEL 408
Query: 261 EEMKTMLVEEKLS--EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
E+ + ++EEKL +++ + K EI+ + L D+RE E M ++ L + +
Sbjct: 409 EKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREI-ERMTAESRALQSCVECL 467
Query: 319 NKTERELEEK----QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+K + +L+EK +++L L E NS K+ ++ K+ + + +L EL
Sbjct: 468 SKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS-KMEQSNLEKL-----ELNV-RKLQQEL 520
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
D + +++SL N I+ + Q+ E ++ N+ ++++A++ + + K+
Sbjct: 521 DQLNR---DKLSLH-----NDISAMQQQLQEKREAVNS-----LQEELANVQDHLNLAKQ 567
Query: 435 RLSQLETENKELLIEIQT-VRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
L T+++++L+ QT ++ E +D NEIE+ K K++
Sbjct: 568 DLLHT-TKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLV 626
Query: 494 EWKSQFEDLDDVMKQQQKELKLGK 517
+ + F+ L + ++ +L+ K
Sbjct: 627 QQEMMFQRLQKERESEESKLETSK 650
Score = 48.0 bits (109), Expect = 8e-05
Identities = 70/312 (22%), Positives = 135/312 (43%), Gaps = 24/312 (7%)
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKN-ETDINELRNSIKYLESVKSEYNTANEK 203
EE L++ L++ S K +K +LD L +N E +L++ + E K++ EK
Sbjct: 362 EEENLQVVLRQMS--KHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 419
Query: 204 L-FEQLNNAVDKQNC-IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
L E L +Q I+ + LL+ + + + + ++ +L+
Sbjct: 420 LELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKE----DLQ 475
Query: 262 EMKTMLVEEKLSEIKE----KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
E K + E+KL++ K +EN K E L EKL + R+ + + + N L
Sbjct: 476 E-KCDIWEKKLAQTKRVLAAAEENSKMEQSNL-EKLELNVRKLQQELDQLNRDKLSLHND 533
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD-D 376
++ +++L+EK+E + L E+L + +++ +++ + D +S Q + D
Sbjct: 534 ISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKH--QDVLLSEQTRLQKDIS 591
Query: 377 ESENTYERISLTLDKITNHITYLNTQINET------QKNDNAQLLWEAKKQIADLTEQNI 430
E N +E + + L +I E Q+ +L E + + + L +
Sbjct: 592 EWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKV 651
Query: 431 ILKERLSQLETE 442
LKE+ QLE E
Sbjct: 652 TLKEQQHQLEKE 663
Score = 39.5 bits (88), Expect = 0.028
Identities = 44/213 (20%), Positives = 97/213 (45%), Gaps = 21/213 (9%)
Query: 259 NLEEMKTMLVE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
++ M+ L E E ++ ++E+ N + +++ + L+ + + + E+ L D+S+
Sbjct: 533 DISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISE 592
Query: 317 KVNKTE---RELEEKQEQLTHLMEQLNDTENNSYKLI--ENMFNKVSQIASDFKISNQLS 371
N+ E +E E KQ+QL L N+ E N KL+ E MF ++ + + + S
Sbjct: 593 WANRFEDCQKEEETKQQQLQVLQ---NEIEENKLKLVQQEMMFQRLQKERESEESKLETS 649
Query: 372 CELDDESENTYERISLT-----LDKITNHITYLNTQINETQKNDN-----AQLLWEAKKQ 421
E ++ E+ LT LD++ + + ++ Q+ + + L + K+Q
Sbjct: 650 KVTLKEQQHQLEK-ELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQ 708
Query: 422 IADLTEQNIILKERLSQLETENKELLIEIQTVR 454
+++ +Q + L L+ E + + +R
Sbjct: 709 LSEREQQLVEKSGELLALQKEADSMRADFSLLR 741
Score = 38.7 bits (86), Expect = 0.049
Identities = 59/337 (17%), Positives = 131/337 (38%), Gaps = 18/337 (5%)
Query: 4 NEATLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMI 63
++ L + ++ I + R E+C KE + QQ + V + E K + +
Sbjct: 575 HQDVLLSEQTRLQKDISEWANRFEDCQKE----EETKQQQLQVLQNEIEENKLKLVQQEM 630
Query: 64 RQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENI--QMHTSDVM 121
T K+T+ E +H L+K D S+L+ + + + + +
Sbjct: 631 MFQRLQKERESEESKLETSKVTLKEQQHQ-LEKELTDQKSKLDQVLSKVLAAEERVRTLQ 689
Query: 122 VVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDIN 181
+SL + ++ E+ +E + ++ K+ S++ D + +N+ +
Sbjct: 690 EEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRA--DFSLLRNQF-LT 746
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
E + + K + S+K +L + L + +CIQ+E+ +++ Q+ +
Sbjct: 747 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMK 806
Query: 242 XXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFN 301
K +AN +++ E + EI + K E+ +++ + N
Sbjct: 807 ELNQMQYEYTELKKQMANQKDL-----ERRQMEISDAMRTLKSEV---KDEIRTSLKNLN 858
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ + E L + ++ E ELE +E L M +
Sbjct: 859 QFLPELPADLEAILERNENLEGELESLKENLPFTMNE 895
>AL137068-5|CAI12358.1| 1773|Homo sapiens centrosomal protein 110kDa
protein.
Length = 1773
Score = 56.0 bits (129), Expect = 3e-07
Identities = 102/504 (20%), Positives = 218/504 (43%), Gaps = 56/504 (11%)
Query: 23 KIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTE 82
KI+ EE KEI ++ + + K +L +E+ + + + L E
Sbjct: 960 KIKQEEILKEINKIVAAKDSDFQCLSKKKEKL-TEELQKLQKDIEMAERNEDHHLQVLKE 1018
Query: 83 KLTIAETKHNDLKKLYEDSASELEALKRENIQM-HTSDVMVVPEIIDSLTEVINTLTNGF 141
+ + K +L+KL S+ + + + Q+ H + + + + S+ + L
Sbjct: 1019 SEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ--GSMVQAKADLQ--- 1073
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETDINELRNSIKYLESVKSEYNTA 200
E+L E+ K N I + +K+LL++L K E ++ ++ L +K E
Sbjct: 1074 EALRLGETEVTEKCNHIRE----VKSLLEELSFQKGELNV-QISERKTQLTLIKQEIEKE 1128
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L L + ++ +D+L++EN L D+ ++ L
Sbjct: 1129 EENLQVVLRQMSKHKTELKNILDMLQLENHEL--------------QGLKLQHDQRVSEL 1174
Query: 261 EEMKTMLVEEKLS--EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
E+ + ++EEKL +++ + K EI+ + L D+RE E M ++ L + +
Sbjct: 1175 EKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREI-ERMTAESRALQSCVECL 1233
Query: 319 NKTERELEEK----QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+K + +L+EK +++L L E NS K+ ++ K+ + + +L EL
Sbjct: 1234 SKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS-KMEQSNLEKL-----ELNV-RKLQQEL 1286
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
D + +++SL N I+ + Q+ E ++ N+ ++++A++ + + K+
Sbjct: 1287 DQLNR---DKLSLH-----NDISAMQQQLQEKREAVNS-----LQEELANVQDHLNLAKQ 1333
Query: 435 RLSQLETENKELLIEIQT-VRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
L T+++++L+ QT ++ E +D NEIE+ K K++
Sbjct: 1334 DLLHT-TKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLV 1392
Query: 494 EWKSQFEDLDDVMKQQQKELKLGK 517
+ + F+ L + ++ +L+ K
Sbjct: 1393 QQEMMFQRLQKERESEESKLETSK 1416
Score = 48.0 bits (109), Expect = 8e-05
Identities = 70/312 (22%), Positives = 135/312 (43%), Gaps = 24/312 (7%)
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKN-ETDINELRNSIKYLESVKSEYNTANEK 203
EE L++ L++ S K +K +LD L +N E +L++ + E K++ EK
Sbjct: 1128 EEENLQVVLRQMS--KHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1185
Query: 204 L-FEQLNNAVDKQNC-IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
L E L +Q I+ + LL+ + + + + ++ +L+
Sbjct: 1186 LELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKE----DLQ 1241
Query: 262 EMKTMLVEEKLSEIKE----KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
E K + E+KL++ K +EN K E L EKL + R+ + + + N L
Sbjct: 1242 E-KCDIWEKKLAQTKRVLAAAEENSKMEQSNL-EKLELNVRKLQQELDQLNRDKLSLHND 1299
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD-D 376
++ +++L+EK+E + L E+L + +++ +++ + D +S Q + D
Sbjct: 1300 ISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKH--QDVLLSEQTRLQKDIS 1357
Query: 377 ESENTYERISLTLDKITNHITYLNTQINET------QKNDNAQLLWEAKKQIADLTEQNI 430
E N +E + + L +I E Q+ +L E + + + L +
Sbjct: 1358 EWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKV 1417
Query: 431 ILKERLSQLETE 442
LKE+ QLE E
Sbjct: 1418 TLKEQQHQLEKE 1429
Score = 39.5 bits (88), Expect = 0.028
Identities = 44/213 (20%), Positives = 97/213 (45%), Gaps = 21/213 (9%)
Query: 259 NLEEMKTMLVE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
++ M+ L E E ++ ++E+ N + +++ + L+ + + + E+ L D+S+
Sbjct: 1299 DISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISE 1358
Query: 317 KVNKTE---RELEEKQEQLTHLMEQLNDTENNSYKLI--ENMFNKVSQIASDFKISNQLS 371
N+ E +E E KQ+QL L N+ E N KL+ E MF ++ + + + S
Sbjct: 1359 WANRFEDCQKEEETKQQQLQVLQ---NEIEENKLKLVQQEMMFQRLQKERESEESKLETS 1415
Query: 372 CELDDESENTYERISLT-----LDKITNHITYLNTQINETQKNDN-----AQLLWEAKKQ 421
E ++ E+ LT LD++ + + ++ Q+ + + L + K+Q
Sbjct: 1416 KVTLKEQQHQLEK-ELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQ 1474
Query: 422 IADLTEQNIILKERLSQLETENKELLIEIQTVR 454
+++ +Q + L L+ E + + +R
Sbjct: 1475 LSEREQQLVEKSGELLALQKEADSMRADFSLLR 1507
Score = 38.7 bits (86), Expect = 0.049
Identities = 59/337 (17%), Positives = 131/337 (38%), Gaps = 18/337 (5%)
Query: 4 NEATLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMI 63
++ L + ++ I + R E+C KE + QQ + V + E K + +
Sbjct: 1341 HQDVLLSEQTRLQKDISEWANRFEDCQKE----EETKQQQLQVLQNEIEENKLKLVQQEM 1396
Query: 64 RQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENI--QMHTSDVM 121
T K+T+ E +H L+K D S+L+ + + + + +
Sbjct: 1397 MFQRLQKERESEESKLETSKVTLKEQQHQ-LEKELTDQKSKLDQVLSKVLAAEERVRTLQ 1455
Query: 122 VVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDIN 181
+SL + ++ E+ +E + ++ K+ S++ D + +N+ +
Sbjct: 1456 EEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRA--DFSLLRNQF-LT 1512
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
E + + K + S+K +L + L + +CIQ+E+ +++ Q+ +
Sbjct: 1513 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMK 1572
Query: 242 XXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFN 301
K +AN +++ E + EI + K E+ +++ + N
Sbjct: 1573 ELNQMQYEYTELKKQMANQKDL-----ERRQMEISDAMRTLKSEV---KDEIRTSLKNLN 1624
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ + E L + ++ E ELE +E L M +
Sbjct: 1625 QFLPELPADLEAILERNENLEGELESLKENLPFTMNE 1661
>AL137068-2|CAM13285.1| 2325|Homo sapiens centrosomal protein 110kDa
protein.
Length = 2325
Score = 56.0 bits (129), Expect = 3e-07
Identities = 102/504 (20%), Positives = 218/504 (43%), Gaps = 56/504 (11%)
Query: 23 KIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTE 82
KI+ EE KEI ++ + + K +L +E+ + + + L E
Sbjct: 1512 KIKQEEILKEINKIVAAKDSDFQCLSKKKEKL-TEELQKLQKDIEMAERNEDHHLQVLKE 1570
Query: 83 KLTIAETKHNDLKKLYEDSASELEALKRENIQM-HTSDVMVVPEIIDSLTEVINTLTNGF 141
+ + K +L+KL S+ + + + Q+ H + + + + S+ + L
Sbjct: 1571 SEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ--GSMVQAKADLQ--- 1625
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETDINELRNSIKYLESVKSEYNTA 200
E+L E+ K N I + +K+LL++L K E ++ ++ L +K E
Sbjct: 1626 EALRLGETEVTEKCNHIRE----VKSLLEELSFQKGELNV-QISERKTQLTLIKQEIEKE 1680
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L L + ++ +D+L++EN L D+ ++ L
Sbjct: 1681 EENLQVVLRQMSKHKTELKNILDMLQLENHEL--------------QGLKLQHDQRVSEL 1726
Query: 261 EEMKTMLVEEKLS--EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
E+ + ++EEKL +++ + K EI+ + L D+RE E M ++ L + +
Sbjct: 1727 EKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREI-ERMTAESRALQSCVECL 1785
Query: 319 NKTERELEEK----QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+K + +L+EK +++L L E NS K+ ++ K+ + + +L EL
Sbjct: 1786 SKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS-KMEQSNLEKL-----ELNV-RKLQQEL 1838
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
D + +++SL N I+ + Q+ E ++ N+ ++++A++ + + K+
Sbjct: 1839 DQLNR---DKLSLH-----NDISAMQQQLQEKREAVNS-----LQEELANVQDHLNLAKQ 1885
Query: 435 RLSQLETENKELLIEIQT-VRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
L T+++++L+ QT ++ E +D NEIE+ K K++
Sbjct: 1886 DLLHT-TKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLV 1944
Query: 494 EWKSQFEDLDDVMKQQQKELKLGK 517
+ + F+ L + ++ +L+ K
Sbjct: 1945 QQEMMFQRLQKERESEESKLETSK 1968
Score = 48.0 bits (109), Expect = 8e-05
Identities = 70/312 (22%), Positives = 135/312 (43%), Gaps = 24/312 (7%)
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKN-ETDINELRNSIKYLESVKSEYNTANEK 203
EE L++ L++ S K +K +LD L +N E +L++ + E K++ EK
Sbjct: 1680 EEENLQVVLRQMS--KHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1737
Query: 204 L-FEQLNNAVDKQNC-IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
L E L +Q I+ + LL+ + + + + ++ +L+
Sbjct: 1738 LELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKE----DLQ 1793
Query: 262 EMKTMLVEEKLSEIKE----KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
E K + E+KL++ K +EN K E L EKL + R+ + + + N L
Sbjct: 1794 E-KCDIWEKKLAQTKRVLAAAEENSKMEQSNL-EKLELNVRKLQQELDQLNRDKLSLHND 1851
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD-D 376
++ +++L+EK+E + L E+L + +++ +++ + D +S Q + D
Sbjct: 1852 ISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKH--QDVLLSEQTRLQKDIS 1909
Query: 377 ESENTYERISLTLDKITNHITYLNTQINET------QKNDNAQLLWEAKKQIADLTEQNI 430
E N +E + + L +I E Q+ +L E + + + L +
Sbjct: 1910 EWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKV 1969
Query: 431 ILKERLSQLETE 442
LKE+ QLE E
Sbjct: 1970 TLKEQQHQLEKE 1981
Score = 39.5 bits (88), Expect = 0.028
Identities = 44/213 (20%), Positives = 97/213 (45%), Gaps = 21/213 (9%)
Query: 259 NLEEMKTMLVE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
++ M+ L E E ++ ++E+ N + +++ + L+ + + + E+ L D+S+
Sbjct: 1851 DISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISE 1910
Query: 317 KVNKTE---RELEEKQEQLTHLMEQLNDTENNSYKLI--ENMFNKVSQIASDFKISNQLS 371
N+ E +E E KQ+QL L N+ E N KL+ E MF ++ + + + S
Sbjct: 1911 WANRFEDCQKEEETKQQQLQVLQ---NEIEENKLKLVQQEMMFQRLQKERESEESKLETS 1967
Query: 372 CELDDESENTYERISLT-----LDKITNHITYLNTQINETQKNDN-----AQLLWEAKKQ 421
E ++ E+ LT LD++ + + ++ Q+ + + L + K+Q
Sbjct: 1968 KVTLKEQQHQLEK-ELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQ 2026
Query: 422 IADLTEQNIILKERLSQLETENKELLIEIQTVR 454
+++ +Q + L L+ E + + +R
Sbjct: 2027 LSEREQQLVEKSGELLALQKEADSMRADFSLLR 2059
Score = 38.7 bits (86), Expect = 0.049
Identities = 59/337 (17%), Positives = 131/337 (38%), Gaps = 18/337 (5%)
Query: 4 NEATLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMI 63
++ L + ++ I + R E+C KE + QQ + V + E K + +
Sbjct: 1893 HQDVLLSEQTRLQKDISEWANRFEDCQKE----EETKQQQLQVLQNEIEENKLKLVQQEM 1948
Query: 64 RQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENI--QMHTSDVM 121
T K+T+ E +H L+K D S+L+ + + + + +
Sbjct: 1949 MFQRLQKERESEESKLETSKVTLKEQQHQ-LEKELTDQKSKLDQVLSKVLAAEERVRTLQ 2007
Query: 122 VVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDIN 181
+SL + ++ E+ +E + ++ K+ S++ D + +N+ +
Sbjct: 2008 EEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRA--DFSLLRNQF-LT 2064
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
E + + K + S+K +L + L + +CIQ+E+ +++ Q+ +
Sbjct: 2065 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMK 2124
Query: 242 XXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFN 301
K +AN +++ E + EI + K E+ +++ + N
Sbjct: 2125 ELNQMQYEYTELKKQMANQKDL-----ERRQMEISDAMRTLKSEV---KDEIRTSLKNLN 2176
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ + E L + ++ E ELE +E L M +
Sbjct: 2177 QFLPELPADLEAILERNENLEGELESLKENLPFTMNE 2213
>AK074079-1|BAB84905.1| 1793|Homo sapiens FLJ00150 protein protein.
Length = 1793
Score = 56.0 bits (129), Expect = 3e-07
Identities = 102/504 (20%), Positives = 218/504 (43%), Gaps = 56/504 (11%)
Query: 23 KIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTE 82
KI+ EE KEI ++ + + K +L +E+ + + + L E
Sbjct: 980 KIKQEEILKEINKIVAAKDSDFQCLSKKKEKL-TEELQKLQKDIEMAERNEDHHLQVLKE 1038
Query: 83 KLTIAETKHNDLKKLYEDSASELEALKRENIQM-HTSDVMVVPEIIDSLTEVINTLTNGF 141
+ + K +L+KL S+ + + + Q+ H + + + + S+ + L
Sbjct: 1039 SEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ--GSMVQAKADLQ--- 1093
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETDINELRNSIKYLESVKSEYNTA 200
E+L E+ K N I + +K+LL++L K E ++ ++ L +K E
Sbjct: 1094 EALRLGETEVTEKCNHIRE----VKSLLEELSFQKGELNV-QISERKTQLTLIKQEIEKE 1148
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L L + ++ +D+L++EN L D+ ++ L
Sbjct: 1149 EENLQVVLRQMSKHKTELKNILDMLQLENHEL--------------QGLKLQHDQRVSEL 1194
Query: 261 EEMKTMLVEEKLS--EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
E+ + ++EEKL +++ + K EI+ + L D+RE E M ++ L + +
Sbjct: 1195 EKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREI-ERMTAESRALQSCVECL 1253
Query: 319 NKTERELEEK----QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+K + +L+EK +++L L E NS K+ ++ K+ + + +L EL
Sbjct: 1254 SKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS-KMEQSNLEKL-----ELNV-RKLQQEL 1306
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
D + +++SL N I+ + Q+ E ++ N+ ++++A++ + + K+
Sbjct: 1307 DQLNR---DKLSLH-----NDISAMQQQLQEKREAVNS-----LQEELANVQDHLNLAKQ 1353
Query: 435 RLSQLETENKELLIEIQT-VRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
L T+++++L+ QT ++ E +D NEIE+ K K++
Sbjct: 1354 DLLHT-TKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLV 1412
Query: 494 EWKSQFEDLDDVMKQQQKELKLGK 517
+ + F+ L + ++ +L+ K
Sbjct: 1413 QQEMMFQRLQKERESEESKLETSK 1436
Score = 48.0 bits (109), Expect = 8e-05
Identities = 70/312 (22%), Positives = 135/312 (43%), Gaps = 24/312 (7%)
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKN-ETDINELRNSIKYLESVKSEYNTANEK 203
EE L++ L++ S K +K +LD L +N E +L++ + E K++ EK
Sbjct: 1148 EEENLQVVLRQMS--KHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1205
Query: 204 L-FEQLNNAVDKQNC-IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
L E L +Q I+ + LL+ + + + + ++ +L+
Sbjct: 1206 LELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKE----DLQ 1261
Query: 262 EMKTMLVEEKLSEIKE----KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
E K + E+KL++ K +EN K E L EKL + R+ + + + N L
Sbjct: 1262 E-KCDIWEKKLAQTKRVLAAAEENSKMEQSNL-EKLELNVRKLQQELDQLNRDKLSLHND 1319
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD-D 376
++ +++L+EK+E + L E+L + +++ +++ + D +S Q + D
Sbjct: 1320 ISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKH--QDVLLSEQTRLQKDIS 1377
Query: 377 ESENTYERISLTLDKITNHITYLNTQINET------QKNDNAQLLWEAKKQIADLTEQNI 430
E N +E + + L +I E Q+ +L E + + + L +
Sbjct: 1378 EWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKV 1437
Query: 431 ILKERLSQLETE 442
LKE+ QLE E
Sbjct: 1438 TLKEQQHQLEKE 1449
Score = 39.5 bits (88), Expect = 0.028
Identities = 44/213 (20%), Positives = 97/213 (45%), Gaps = 21/213 (9%)
Query: 259 NLEEMKTMLVE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
++ M+ L E E ++ ++E+ N + +++ + L+ + + + E+ L D+S+
Sbjct: 1319 DISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISE 1378
Query: 317 KVNKTE---RELEEKQEQLTHLMEQLNDTENNSYKLI--ENMFNKVSQIASDFKISNQLS 371
N+ E +E E KQ+QL L N+ E N KL+ E MF ++ + + + S
Sbjct: 1379 WANRFEDCQKEEETKQQQLQVLQ---NEIEENKLKLVQQEMMFQRLQKERESEESKLETS 1435
Query: 372 CELDDESENTYERISLT-----LDKITNHITYLNTQINETQKNDN-----AQLLWEAKKQ 421
E ++ E+ LT LD++ + + ++ Q+ + + L + K+Q
Sbjct: 1436 KVTLKEQQHQLEK-ELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQ 1494
Query: 422 IADLTEQNIILKERLSQLETENKELLIEIQTVR 454
+++ +Q + L L+ E + + +R
Sbjct: 1495 LSEREQQLVEKSGELLALQKEADSMRADFSLLR 1527
Score = 38.7 bits (86), Expect = 0.049
Identities = 59/337 (17%), Positives = 131/337 (38%), Gaps = 18/337 (5%)
Query: 4 NEATLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMI 63
++ L + ++ I + R E+C KE + QQ + V + E K + +
Sbjct: 1361 HQDVLLSEQTRLQKDISEWANRFEDCQKE----EETKQQQLQVLQNEIEENKLKLVQQEM 1416
Query: 64 RQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENI--QMHTSDVM 121
T K+T+ E +H L+K D S+L+ + + + + +
Sbjct: 1417 MFQRLQKERESEESKLETSKVTLKEQQHQ-LEKELTDQKSKLDQVLSKVLAAEERVRTLQ 1475
Query: 122 VVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDIN 181
+SL + ++ E+ +E + ++ K+ S++ D + +N+ +
Sbjct: 1476 EEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRA--DFSLLRNQF-LT 1532
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
E + + K + S+K +L + L + +CIQ+E+ +++ Q+ +
Sbjct: 1533 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMK 1592
Query: 242 XXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFN 301
K +AN +++ E + EI + K E+ +++ + N
Sbjct: 1593 ELNQMQYEYTELKKQMANQKDL-----ERRQMEISDAMRTLKSEV---KDEIRTSLKNLN 1644
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ + E L + ++ E ELE +E L M +
Sbjct: 1645 QFLPELPADLEAILERNENLEGELESLKENLPFTMNE 1681
>AF513978-1|AAP43846.1| 2325|Homo sapiens CENTRIOLIN protein.
Length = 2325
Score = 56.0 bits (129), Expect = 3e-07
Identities = 102/504 (20%), Positives = 218/504 (43%), Gaps = 56/504 (11%)
Query: 23 KIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTE 82
KI+ EE KEI ++ + + K +L +E+ + + + L E
Sbjct: 1512 KIKQEEILKEINKIVAAKDSDFQCLSKKKEKL-TEELQKLQKDIEMAERNEDHHLQVLKE 1570
Query: 83 KLTIAETKHNDLKKLYEDSASELEALKRENIQM-HTSDVMVVPEIIDSLTEVINTLTNGF 141
+ + K +L+KL S+ + + + Q+ H + + + + S+ + L
Sbjct: 1571 SEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLGHKKEELHLLQ--GSMVQAKADLQ--- 1625
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETDINELRNSIKYLESVKSEYNTA 200
E+L E+ K N I + +K+LL++L K E ++ ++ L +K E
Sbjct: 1626 EALRLGETEVTEKCNHIRE----VKSLLEELSFQKGELNV-QISERKTQLTLIKQEIEKE 1680
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L L + ++ +D+L++EN L D+ ++ L
Sbjct: 1681 EENLQVVLRQMSKHKTELKNILDMLQLENHEL--------------QGLKLQHDQRVSEL 1726
Query: 261 EEMKTMLVEEKLS--EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
E+ + ++EEKL +++ + K EI+ + L D+RE E M ++ L + +
Sbjct: 1727 EKTQVAVLEEKLELENLQQISQQQKGEIEWQKQLLERDKREI-ERMTAESRALQSCVECL 1785
Query: 319 NKTERELEEK----QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+K + +L+EK +++L L E NS K+ ++ K+ + + +L EL
Sbjct: 1786 SKEKEDLQEKCDIWEKKLAQTKRVLAAAEENS-KMEQSNLEKL-----ELNV-RKLQQEL 1838
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
D + +++SL N I+ + Q+ E ++ N+ ++++A++ + + K+
Sbjct: 1839 DQLNR---DKLSLH-----NDISAMQQQLQEKREAVNS-----LQEELANVQDHLNLAKQ 1885
Query: 435 RLSQLETENKELLIEIQT-VRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
L T+++++L+ QT ++ E +D NEIE+ K K++
Sbjct: 1886 DLLHT-TKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLV 1944
Query: 494 EWKSQFEDLDDVMKQQQKELKLGK 517
+ + F+ L + ++ +L+ K
Sbjct: 1945 QQEMMFQRLQKERESEESKLETSK 1968
Score = 48.0 bits (109), Expect = 8e-05
Identities = 70/312 (22%), Positives = 135/312 (43%), Gaps = 24/312 (7%)
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKN-ETDINELRNSIKYLESVKSEYNTANEK 203
EE L++ L++ S K +K +LD L +N E +L++ + E K++ EK
Sbjct: 1680 EEENLQVVLRQMS--KHKTELKNILDMLQLENHELQGLKLQHDQRVSELEKTQVAVLEEK 1737
Query: 204 L-FEQLNNAVDKQNC-IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
L E L +Q I+ + LL+ + + + + ++ +L+
Sbjct: 1738 LELENLQQISQQQKGEIEWQKQLLERDKREIERMTAESRALQSCVECLSKEKE----DLQ 1793
Query: 262 EMKTMLVEEKLSEIKE----KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
E K + E+KL++ K +EN K E L EKL + R+ + + + N L
Sbjct: 1794 E-KCDIWEKKLAQTKRVLAAAEENSKMEQSNL-EKLELNVRKLQQELDQLNRDKLSLHND 1851
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD-D 376
++ +++L+EK+E + L E+L + +++ +++ + D +S Q + D
Sbjct: 1852 ISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKH--QDVLLSEQTRLQKDIS 1909
Query: 377 ESENTYERISLTLDKITNHITYLNTQINET------QKNDNAQLLWEAKKQIADLTEQNI 430
E N +E + + L +I E Q+ +L E + + + L +
Sbjct: 1910 EWANRFEDCQKEEETKQQQLQVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKV 1969
Query: 431 ILKERLSQLETE 442
LKE+ QLE E
Sbjct: 1970 TLKEQQHQLEKE 1981
Score = 39.5 bits (88), Expect = 0.028
Identities = 44/213 (20%), Positives = 97/213 (45%), Gaps = 21/213 (9%)
Query: 259 NLEEMKTMLVE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
++ M+ L E E ++ ++E+ N + +++ + L+ + + + E+ L D+S+
Sbjct: 1851 DISAMQQQLQEKREAVNSLQEELANVQDHLNLAKQDLLHTTKHQDVLLSEQTRLQKDISE 1910
Query: 317 KVNKTE---RELEEKQEQLTHLMEQLNDTENNSYKLI--ENMFNKVSQIASDFKISNQLS 371
N+ E +E E KQ+QL L N+ E N KL+ E MF ++ + + + S
Sbjct: 1911 WANRFEDCQKEEETKQQQLQVLQ---NEIEENKLKLVQQEMMFQRLQKERESEESKLETS 1967
Query: 372 CELDDESENTYERISLT-----LDKITNHITYLNTQINETQKNDN-----AQLLWEAKKQ 421
E ++ E+ LT LD++ + + ++ Q+ + + L + K+Q
Sbjct: 1968 KVTLKEQQHQLEK-ELTDQKSKLDQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQ 2026
Query: 422 IADLTEQNIILKERLSQLETENKELLIEIQTVR 454
+++ +Q + L L+ E + + +R
Sbjct: 2027 LSEREQQLVEKSGELLALQKEADSMRADFSLLR 2059
Score = 38.7 bits (86), Expect = 0.049
Identities = 59/337 (17%), Positives = 131/337 (38%), Gaps = 18/337 (5%)
Query: 4 NEATLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMI 63
++ L + ++ I + R E+C KE + QQ + V + E K + +
Sbjct: 1893 HQDVLLSEQTRLQKDISEWANRFEDCQKE----EETKQQQLQVLQNEIEENKLKLVQQEM 1948
Query: 64 RQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENI--QMHTSDVM 121
T K+T+ E +H L+K D S+L+ + + + + +
Sbjct: 1949 MFQRLQKERESEESKLETSKVTLKEQQHQ-LEKELTDQKSKLDQVLSKVLAAEERVRTLQ 2007
Query: 122 VVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDIN 181
+SL + ++ E+ +E + ++ K+ S++ D + +N+ +
Sbjct: 2008 EEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEADSMRA--DFSLLRNQF-LT 2064
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
E + + K + S+K +L + L + +CIQ+E+ +++ Q+ +
Sbjct: 2065 ERKKAEKQVASLKEALKIQRSQLEKNLLEQKQENSCIQKEMATIELVAQDNHERARRLMK 2124
Query: 242 XXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFN 301
K +AN +++ E + EI + K E+ +++ + N
Sbjct: 2125 ELNQMQYEYTELKKQMANQKDL-----ERRQMEISDAMRTLKSEV---KDEIRTSLKNLN 2176
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ + E L + ++ E ELE +E L M +
Sbjct: 2177 QFLPELPADLEAILERNENLEGELESLKENLPFTMNE 2213
>U19769-1|AAA82889.1| 3210|Homo sapiens CENP-F kinetochore protein
protein.
Length = 3210
Score = 55.6 bits (128), Expect = 4e-07
Identities = 98/522 (18%), Positives = 221/522 (42%), Gaps = 46/522 (8%)
Query: 8 LFANNENIRNIIHAFKIRLEECYKEI-GQLKSGLQQNVGVGDKTVAELKNDEINSMIRQL 66
L A N+ +RN I+ ++RL+ KE+ GQ+ + + + +K EL E ++ +
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQL-EKAKVELIEKE--KVLNKC 339
Query: 67 XXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEI 126
+ K T E K LKKL ED + + + + + + E
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQK---LKKLTEDLSCQRQNAESARCSLEQK----IKEK 392
Query: 127 IDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS 186
E ++ F++L++ +++ K +T++ K + + L + ++++L +
Sbjct: 393 EKEFQEELSRQQRSFQTLDQECIQM---KARLTQELQQAKNMHNVL----QAELDKLTSV 445
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
+ LE+ E+ + + + K+N ++ ++ +K EN NLL+
Sbjct: 446 KQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKEN-NLLKSHSEQKAREVCH 504
Query: 247 XXXXXARDKFIANLEEMKTMLVEEK--LSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
A L+ +K L + + E+K K+ + + + L EK+ +++E + T+
Sbjct: 505 LE---------AELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKI--NQQENSLTL 553
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
++ + ++DL K+ + ++ L++++ + L ++L+ TE S L+ + K +
Sbjct: 554 EKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELK 613
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNT-----QINETQKNDNAQLLWEAK 419
+ SC E+E ++ + + + I +L T QI + N+ + L +
Sbjct: 614 EEKTLFSC-WKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDR 672
Query: 420 KQIA-DLTEQNIILKERLSQLETENKELL-----IEIQTVRGSNEEVTLNLKDSSTX--X 471
+ ++ ++ + +L + ++ET+ + E + E + LK S
Sbjct: 673 ENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQV 732
Query: 472 XXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
SNEI D + +++E L D++K + L
Sbjct: 733 EDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASL 774
Score = 52.0 bits (119), Expect = 5e-06
Identities = 101/520 (19%), Positives = 222/520 (42%), Gaps = 47/520 (9%)
Query: 11 NNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVA-ELKNDEINSMIRQLXXX 69
+NEN + +I + L E QL+ L + KT A + ++++ ++L
Sbjct: 2034 DNENKQKVIVCLEEELSVVTSERNQLRGELDT---MSKKTTALDQLSEKMKEKTQELESH 2090
Query: 70 XXX----XXXXXXXLTEKLTIAETKHNDLKKLYEDSA---SELEALKRENIQMHTSDVMV 122
+ EK + +T +D+ +L +D +L++L++++ + + +
Sbjct: 2091 QSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCEL 2150
Query: 123 VPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKD---NISIKTLLDKLITKNETD 179
+I L + L ESL+ E D +K +++K + K ++ + +
Sbjct: 2151 ENQIAQ-LNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEE 2209
Query: 180 INELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXX 239
+++LR I+ L V+ E A+EK +QL+ A +K + E D LK + +NL +
Sbjct: 2210 VHQLRRGIEKLR-VRIE---ADEK--KQLHIA-EKLKERERENDSLKDKVENLERELQMS 2262
Query: 240 XXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDRR 298
++ I + E K VE ++I+E + K E+D++ L ++
Sbjct: 2263 EEN----------QELVILDAENSKAE-VETLKTQIEEMARSLKVFELDLVT--LRSEKE 2309
Query: 299 EFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
+ +QEK LS+L K ++ + LEEK++ + E+ ++ + V+
Sbjct: 2310 NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVA 2369
Query: 359 QIASDFKISNQLSCELDDESE------NTYERISLTLDKITNHITYLNTQINETQKNDNA 412
+ D +I LD E N+ E++ L+ + Q+ E++ +A
Sbjct: 2370 ALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESE--HHA 2427
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
LL K ++ +L + I + E + E++T++ E +T +L+
Sbjct: 2428 DLL---KGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVV 2484
Query: 473 XXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+NE++ + ++ E + +++++++++E
Sbjct: 2485 TIRSEKEDLTNELQKEQERISELEIINSSFENILQEKEQE 2524
Score = 50.0 bits (114), Expect = 2e-05
Identities = 65/285 (22%), Positives = 124/285 (43%), Gaps = 34/285 (11%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD--- 313
I+ L+E T + ++E EN ++E+ +LN+K+ ++ E E +++ N LL D
Sbjct: 885 ISKLQE-DTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQE-LKKSNHLLEDSLK 942
Query: 314 ----------LSKK-----VNKTERELEEKQEQ---LTHLMEQLNDTENNSYKLIENMFN 355
L KK ++ +RE+EE ++ L + LN + N + E+ N
Sbjct: 943 ELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFAN 1002
Query: 356 -------KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINE-TQ 407
+S+++ +K + + +E+ N YE +S + L +NE T
Sbjct: 1003 YIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTS 1062
Query: 408 KNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS-NEEVTLNLKD 466
+N + E K+ Q + K L+ E N+ L++E++TV+ + E+T N +
Sbjct: 1063 LCENRKNELEQLKEAFAKEHQEFLTK--LAFAEERNQNLMLELETVQQALRSEMTDNQNN 1120
Query: 467 SSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
S + E M+ +V + + E L VMK + +
Sbjct: 1121 SKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHE 1165
Score = 49.2 bits (112), Expect = 3e-05
Identities = 86/416 (20%), Positives = 176/416 (42%), Gaps = 46/416 (11%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELE------ALKRENIQMHTSDVMVVPEIIDS-LTE 132
L E ++ E + N+L++L E A E + A E Q ++ V + + S +T+
Sbjct: 1057 LNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTD 1116
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISI----KTLLDKLITKNETDINE---LRN 185
N + L++ + + ++N + K+ + + L+ + TK+E E +RN
Sbjct: 1117 NQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRN 1176
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
S+K ES +++ N + E ++D N +++ + + N+ L
Sbjct: 1177 SVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAM-LRNKELKLQESEKEKECLQ 1235
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQ 305
D +NL++M++ +++S +K+ EID EK I E + +
Sbjct: 1236 HELQTIRGDLETSNLQDMQS----QEISGLKDC------EIDA-EEKYISGPHELSTSQN 1284
Query: 306 EKNILLSDLS---KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
+ L L K+N+ E+ E Q + L+ +LND+ + M +V ++ +
Sbjct: 1285 DNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEVGKLLN 1344
Query: 363 DFKISNQ----LSCELDD--------ESENTYERISLTLDKITNHITYLNTQINETQKND 410
+ KI N L EL + E N +SL +N +L E Q +
Sbjct: 1345 EVKILNDDSGLLHGELVEDIPGGEFGEQPNEQHPVSLAPLDESNSYEHLTLSDKEVQMH- 1403
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
E +++ L ++ IL ++ Q+ ++ EL + +++ N ++ NL++
Sbjct: 1404 ----FAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDSLKAENLVLSTNLRN 1455
Score = 45.2 bits (102), Expect = 6e-04
Identities = 52/264 (19%), Positives = 117/264 (44%), Gaps = 20/264 (7%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNE------TMQEKNILL 311
A+LE ++T EKL +++ +EN ++ I L E+L E N+ TM +K L
Sbjct: 2019 ADLEVVQT----EKLC-LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTAL 2073
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
LS+K+ + +ELE Q + H ++ +L++ + + VS++ D +
Sbjct: 2074 DQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKL 2133
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
L+ +S + +SLT ++ N I LN + E ++ L +A+ +D + N+
Sbjct: 2134 QSLEKDS----QALSLTKCELENQIAQLNKE-KELLVKESESL--QARLSESDYEKLNV- 2185
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
+ L E E + + + + ++ ++ + ++++ + +
Sbjct: 2186 -SKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERE 2244
Query: 492 VMEWKSQFEDLDDVMKQQQKELKL 515
K + E+L+ ++ ++ +L
Sbjct: 2245 NDSLKDKVENLERELQMSEENQEL 2268
Score = 43.2 bits (97), Expect = 0.002
Identities = 56/264 (21%), Positives = 111/264 (42%), Gaps = 15/264 (5%)
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL---ICDRREFNETMQEKNILLSDLS 315
+L+E++ M E E+++ K+E L+EKL CD +E + ++ L SDL
Sbjct: 1908 HLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLE 1967
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+K+ R E + + ++ND+ + +EN +++ + + L E D
Sbjct: 1968 MHADKSSR------EDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIE-HEALYLEAD 2020
Query: 376 DESENTYERISLTLDKITNH--ITYLNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNII 431
E T E++ L D I L +++ +++N L K+ L + +
Sbjct: 2021 LEVVQT-EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEK 2079
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
+KE+ +LE+ E L IQ +E T L+ S+ +++ ++
Sbjct: 2080 MKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKD 2139
Query: 492 VMEWKSQFEDLDDVMKQQQKELKL 515
+L++ + Q KE +L
Sbjct: 2140 SQALSLTKCELENQIAQLNKEKEL 2163
Score = 42.7 bits (96), Expect = 0.003
Identities = 87/485 (17%), Positives = 188/485 (38%), Gaps = 21/485 (4%)
Query: 35 QLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDL 94
Q + L+ G+ + K + + +R L LT +L + + ++L
Sbjct: 2448 QEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISEL 2507
Query: 95 KKLYEDSASELEALKRENIQMH--TSDVMVVPEI-IDSLTEVINTLTNGFESLEEVALEI 151
+ + + L+ ++E +QM +S M + + + L E + L N E+ + +
Sbjct: 2508 EIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNL 2567
Query: 152 DLKKNSITKDNISIKTLLDK-----LITKNETD--INELRNSIKYLESVKSEYNTANEKL 204
+ + + + LD+ ++ ++ + I E+ + + LE E + ++
Sbjct: 2568 SSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQI 2627
Query: 205 FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMK 264
+Q V K + ++ E L K +N L + + L+
Sbjct: 2628 QDQ-EQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSY 2686
Query: 265 TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L E +L K +F ++++ + K +RE +E Q+ L +LS + N+ E
Sbjct: 2687 KNL-ENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGE 2745
Query: 325 LEEKQEQLTHLMEQLND--TENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
L+ E++ +QL + EN+ K + +K Q+ + K+ +++ E
Sbjct: 2746 LQLLLEEIKSSKDQLKELTLENSELKKSLDCMHK-DQVEKEGKVREEIAEYQLRLHEAEK 2804
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
+ +L LD TN + Q + + L K +I DL + + KE L+
Sbjct: 2805 KHQALLLD--TNKQYEVEIQTYREKLTSKEECLSSQKLEI-DLLKSS---KEELNNSLKA 2858
Query: 443 NKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDL 502
++L E++ + N + LK + ++E+ K + + SQ +
Sbjct: 2859 TTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAA 2918
Query: 503 DDVMK 507
+ K
Sbjct: 2919 QEKQK 2923
Score = 37.1 bits (82), Expect = 0.15
Identities = 28/127 (22%), Positives = 62/127 (48%), Gaps = 16/127 (12%)
Query: 389 LDKITNHITYLNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++ + N + L+++++ E Q + E +K + +L ++N L E+L +++EL
Sbjct: 1893 VESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQEL 1952
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME-WKSQFEDLDDV 505
L ++T G N ++ ++ SS +I D KV + WK +F D+++
Sbjct: 1953 LQRVETSEGLNSDLEMHADKSS-------------REDIGDNVAKVNDSWKERFLDVENE 1999
Query: 506 MKQQQKE 512
+ + + E
Sbjct: 2000 LSRIRSE 2006
Score = 33.5 bits (73), Expect = 1.8
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 284 QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ-LNDT 342
+E++ L E + E M+ + I+ + K++ + E+ L ++++L L +Q L++
Sbjct: 1646 EELESLCEVYRQSLEKLEEKMESQGIMKN---KEIQELEQLLSSERQELDCLRKQYLSEN 1702
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
E KL S++A++ K + QLS EL+
Sbjct: 1703 EQWQQKLTSVTLEMESKLAAEKKQTEQLSLELE 1735
Score = 33.1 bits (72), Expect = 2.4
Identities = 37/196 (18%), Positives = 76/196 (38%), Gaps = 3/196 (1%)
Query: 325 LEEKQEQLTH-LMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
LE+K ++LT L Q + E+ L + + K + + + LD E
Sbjct: 360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Query: 384 RISLTLDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
R++ L + N L ++++ + K L E K+++ + + + ++L
Sbjct: 420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRR 479
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+E+ E ++ +E+ + N E+MK K ++ D
Sbjct: 480 SMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRD 539
Query: 502 LDDVMKQQQKELKLGK 517
L + + QQ+ L L K
Sbjct: 540 LQEKINQQENSLTLEK 555
Score = 32.3 bits (70), Expect = 4.2
Identities = 20/93 (21%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+K+ + E +L++ +++ QL+ E K + + N+ ++ ++ K NQ E+
Sbjct: 18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAAPQKQTQKVENEKTE-GTNLKRENQRLMEIC 76
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQK 408
+ E T ++IS L + + + Q+N +K
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKK 109
>BC132736-1|AAI32737.1| 1843|Homo sapiens KIAA1212 protein.
Length = 1843
Score = 55.6 bits (128), Expect = 4e-07
Identities = 93/450 (20%), Positives = 188/450 (41%), Gaps = 38/450 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMV--VPEIIDSLTEVINTLTN 139
E+L I+ + L+K + E L+++ Q+ + + EI D+ E N
Sbjct: 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Query: 140 GFESLEE-VALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYN 198
E + ++ EI + K S + L +L +N+ + IK L +++ +
Sbjct: 861 NLEKENKTLSKEIGIYKESCVR--------LKELEKENKELVKRATIDIKTLVTLREDL- 911
Query: 199 TANEKL-FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD-KF 256
+EKL +Q+NN ++K + E++ + + + LL K
Sbjct: 912 -VSEKLKTQQMNNDLEK---LTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKK 967
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL-ICDRREFNETMQEKNILLSDLS 315
++E K +E +L E ++ +QE+ + + +R+ E M + + +S
Sbjct: 968 SLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS---PPIS 1024
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+ NK ERE +E +L + ++L + E N+ L +Q+ +N L ++
Sbjct: 1025 GEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL 1084
Query: 376 DESENTY--ERISLTLDKITNHITYLNTQINETQK---NDNAQLLWEAKKQIADLTEQNI 430
T + + TL + N+ +N N NAQLL + Q + E
Sbjct: 1085 ALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ---QSSLENENES 1141
Query: 431 ILKERLSQLETENKELL-----IEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEI 485
++KER L++ L+ +E+ R ++E +L K + ++
Sbjct: 1142 VIKER-EDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEH--RDL 1198
Query: 486 EDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
ED ++++ K Q EDL+ ++K +Q+++ L
Sbjct: 1199 EDRYNQLLKQKGQLEDLEKMLKVEQEKMLL 1228
Score = 52.4 bits (120), Expect = 4e-06
Identities = 89/436 (20%), Positives = 200/436 (45%), Gaps = 55/436 (12%)
Query: 53 ELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIA----ETKHNDLKKLYEDSASELEAL 108
+L+N E+ S QL TE+L ++ + ++ L+K E+S +++ L
Sbjct: 724 QLENKELESEKEQLKKGLELLKASFKK-TERLEVSYQGLDIENQRLQKTLENSNKKIQQL 782
Query: 109 KRE--NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIK 166
+ E +++M + E + ++ + L +SLE+ +++ K + K+N K
Sbjct: 783 ESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN---K 839
Query: 167 TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLK 226
L + K +T + E N++K + +++ E T ++++ + K++C++ + L+
Sbjct: 840 RLRQQAEIK-DTTLEE--NNVK-IGNLEKENKTLSKEI------GIYKESCVR--LKELE 887
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEI 286
EN+ L++ R+ ++ E++KT + L ++ + E +I
Sbjct: 888 KENKELVKRATIDIKTLVTL------REDLVS--EKLKTQQMNNDLEKLTHELE----KI 935
Query: 287 DMLNEKLICDRREFNETMQE--KNILLSDLSKKVNKTERE---LEEKQEQLTHLMEQLND 341
+ E+L+ D + +++ + ++ L S L K + E + LE + E+ T+ +QL
Sbjct: 936 GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQ 995
Query: 342 ---TENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKIT----N 394
T +Y+ ++ ++ + S IS + + + + ES+ T + D++ N
Sbjct: 996 ELKTVKKNYEALKQRQDEERMVQSSPPISGEDN-KWERESQETTRELLKVKDRLIEVERN 1054
Query: 395 HITY------LNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
+ T L TQ+ ETQ N+ + ++Q L EQN L+ + ++L+ EN L
Sbjct: 1055 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Query: 447 LIEIQTVRGSNEEVTL 462
+ ++ N ++ +
Sbjct: 1115 NSQSTSLMNQNAQLLI 1130
Score = 51.6 bits (118), Expect = 6e-06
Identities = 108/502 (21%), Positives = 204/502 (40%), Gaps = 38/502 (7%)
Query: 24 IRLEECYKEIGQLKS----GLQQNVGVGDKTVAE-LKNDEINSMIRQLXXXXXXXXXXXX 78
+RL+E KE +L ++ V + + V+E LK ++N+ + +L
Sbjct: 881 VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKE 940
Query: 79 XLT-EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTL 137
L ++ + ++++ L+ E + + +K E I + + L + + T+
Sbjct: 941 RLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTV 1000
Query: 138 TNGFESLEEVALEIDLKKNSIT---KDNI----SIKTLLDKLITKNETDINELRNSIKYL 190
+E+L++ E + ++S +DN S +T + L K+ + E+ + L
Sbjct: 1001 KKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDR--LIEVERNNATL 1058
Query: 191 ESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXX 250
++ K T ++L Q NN + +Q + L+ +N L
Sbjct: 1059 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQS 1118
Query: 251 XARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDML---NEKL-ICDRREFNE--TM 304
+ A L ++ L E S IKE+ E+ K D L +EKL + R+ +E ++
Sbjct: 1119 TSLMNQNAQLLIQQSSLENENESVIKER-EDLKSLYDSLIKDHEKLELLHERQASEYESL 1177
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF--NKVSQ-IA 361
K+ L K + R+LE++ QL QL D E E M NK + +A
Sbjct: 1178 ISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVA 1237
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKI-TNHITYL----NTQINETQKNDNAQLLW 416
+++K C +D +TY ++ + + T+H N+++ +T+ L
Sbjct: 1238 AEYK----KLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLK 1293
Query: 417 EAKKQI----ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
E +Q+ L Q +L + LE EN+ LL +IQT+ N + +S
Sbjct: 1294 EQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFH 1353
Query: 473 XXXXXXXXXSNEIEDMKTKVME 494
NE+ K K+ E
Sbjct: 1354 VEQRQYIDKLNELRRQKEKLEE 1375
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
E+ Q ++ L+D K+ + +ELEEK EQL ++L E +L + N +S
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 303
Query: 362 SDFKISNQLSC--ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
S ++L E + +S +++ + I + ++ E K DN Q+L E K
Sbjct: 304 SARMYRDELDALREKAVRVDKLESEVSRYKERL-HDIEFYKARVEEL-KEDN-QVLLETK 360
Query: 420 KQIADLTEQNIILKERLSQLETENKEL 446
+ D E ++L +LE EN +L
Sbjct: 361 TMLEDQLEGTRARSDKLHELEKENLQL 387
Score = 49.6 bits (113), Expect = 3e-05
Identities = 77/429 (17%), Positives = 182/429 (42%), Gaps = 26/429 (6%)
Query: 99 EDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
E +AS++ +++EN ++ ++ EI+ + N + ++E A L+K
Sbjct: 487 EGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA---QLEKTIE 543
Query: 159 TKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTA-----NEKLFEQLNNAVD 213
T S + + K++ + +N+ +S++ + +E N+ L E +
Sbjct: 544 TLRENSERQI--KILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSS 601
Query: 214 KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLS 273
K + I+ E +K E ++ + + + +K + EK+
Sbjct: 602 KLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLK--ITCEKIE 659
Query: 274 EIKEKDENFKQEIDMLNEKLICDRR-EFN-ETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
+++++ ++E L + L + F E+++++N L + + ++ + L+ +
Sbjct: 660 ALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMK 719
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD-ESENTYERISLTLD 390
+ L QL + E S K E + + + + FK + +L + EN +R+ TL+
Sbjct: 720 MAQL--QLENKELESEK--EQLKKGLELLKASFKKTERLEVSYQGLDIEN--QRLQKTLE 773
Query: 391 KITNHITYLNTQINETQKND-----NAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
I L +++ + + + N + L + K++ L ++N L++ SQLE + K+
Sbjct: 774 NSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Query: 446 LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDV 505
L E + +R E L++++ S EI K + K ++ ++
Sbjct: 834 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKEL 893
Query: 506 MKQQQKELK 514
+K+ ++K
Sbjct: 894 VKRATIDIK 902
Score = 35.1 bits (77), Expect = 0.60
Identities = 83/452 (18%), Positives = 176/452 (38%), Gaps = 30/452 (6%)
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
+ + + D++ L ++ A L+ L E + H+ ++ + E D L + + ++
Sbjct: 176 MEVTDMSQEDIEPLLKNMALHLKRLIDERDE-HSETIIELSEERDGLHFLPHASSSAQSP 234
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
++ + ++ + K + +L + E +L + + LE ++ E ++
Sbjct: 235 CGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE 294
Query: 204 LFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN-- 259
L++A + ++E+D L K + L+ AR + +
Sbjct: 295 NMNLLSDARSAR-MYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDN 353
Query: 260 --LEEMKTMLVEE---------KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
L E KTML ++ KL E+++++ K ++ + + DR++ E M+E N
Sbjct: 354 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE-N 412
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN 368
+ L K+ L + EQ++ E L++ S L + S ++ N
Sbjct: 413 MTLEMAQKQSMDESLHLGWELEQISRTSE-LSEAPQKS--LGHEVNELTSSRLLKLEMEN 469
Query: 369 QLSCELDDESENTYERISLTLDKI-----TNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
Q + +E T + + KI N +I E + Q L +
Sbjct: 470 QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 529
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL-NLKDSSTXXXXXXXXXXXXS 482
DL ++ L++ + L EN E I+I + T+ +L+ S
Sbjct: 530 DLMKEKAQLEKTIETLR-ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE 588
Query: 483 NEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
N+I + + E S+ ++ +Q +KEL+
Sbjct: 589 NKI--LHESIKETSSKLSKIEFEKRQIKKELE 618
>AL445666-1|CAH71810.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 55.6 bits (128), Expect = 4e-07
Identities = 98/522 (18%), Positives = 221/522 (42%), Gaps = 46/522 (8%)
Query: 8 LFANNENIRNIIHAFKIRLEECYKEI-GQLKSGLQQNVGVGDKTVAELKNDEINSMIRQL 66
L A N+ +RN I+ ++RL+ KE+ GQ+ + + + +K EL E ++ +
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQL-EKAKVELIEKE--KVLNKC 339
Query: 67 XXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEI 126
+ K T E K LKKL ED + + + + + + E
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQK---LKKLTEDLSCQRQNAESARCSLEQK----IKEK 392
Query: 127 IDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS 186
E ++ F++L++ +++ K +T++ K + + L + ++++L +
Sbjct: 393 EKEFQEELSRQQRSFQTLDQECIQM---KARLTQELQQAKNMHNVL----QAELDKLTSV 445
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
+ LE+ E+ + + + K+N ++ ++ +K EN NLL+
Sbjct: 446 KQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKEN-NLLKSHSEQKAREVCH 504
Query: 247 XXXXXARDKFIANLEEMKTMLVEEK--LSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
A L+ +K L + + E+K K+ + + + L EK+ +++E + T+
Sbjct: 505 LE---------AELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKI--NQQENSLTL 553
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
++ + ++DL K+ + ++ L++++ + L ++L+ TE S L+ + K +
Sbjct: 554 EKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELK 613
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNT-----QINETQKNDNAQLLWEAK 419
+ SC E+E ++ + + + I +L T QI + N+ + L +
Sbjct: 614 EEKTLFSC-WKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDR 672
Query: 420 KQIA-DLTEQNIILKERLSQLETENKELL-----IEIQTVRGSNEEVTLNLKDSSTX--X 471
+ ++ ++ + +L + ++ET+ + E + E + LK S
Sbjct: 673 ENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQV 732
Query: 472 XXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
SNEI D + +++E L D++K + L
Sbjct: 733 EDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASL 774
Score = 52.0 bits (119), Expect = 5e-06
Identities = 101/520 (19%), Positives = 222/520 (42%), Gaps = 47/520 (9%)
Query: 11 NNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVA-ELKNDEINSMIRQLXXX 69
+NEN + +I + L E QL+ L + KT A + ++++ ++L
Sbjct: 1938 DNENKQKVIVCLEEELSVVTSERNQLRGELDT---MSKKTTALDQLSEKMKEKTQELESH 1994
Query: 70 XXX----XXXXXXXLTEKLTIAETKHNDLKKLYEDSA---SELEALKRENIQMHTSDVMV 122
+ EK + +T +D+ +L +D +L++L++++ + + +
Sbjct: 1995 QSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCEL 2054
Query: 123 VPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKD---NISIKTLLDKLITKNETD 179
+I L + L ESL+ E D +K +++K + K ++ + +
Sbjct: 2055 ENQIAQ-LNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEE 2113
Query: 180 INELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXX 239
+++LR I+ L V+ E A+EK +QL+ A +K + E D LK + +NL +
Sbjct: 2114 VHQLRRGIEKLR-VRIE---ADEK--KQLHIA-EKLKERERENDSLKDKVENLERELQMS 2166
Query: 240 XXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDRR 298
++ I + E K VE ++I+E + K E+D++ L ++
Sbjct: 2167 EEN----------QELVILDAENSKAE-VETLKTQIEEMARSLKVFELDLVT--LRSEKE 2213
Query: 299 EFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
+ +QEK LS+L K ++ + LEEK++ + E+ ++ + V+
Sbjct: 2214 NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVA 2273
Query: 359 QIASDFKISNQLSCELDDESE------NTYERISLTLDKITNHITYLNTQINETQKNDNA 412
+ D +I LD E N+ E++ L+ + Q+ E++ +A
Sbjct: 2274 ALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESE--HHA 2331
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
LL K ++ +L + I + E + E++T++ E +T +L+
Sbjct: 2332 DLL---KGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVV 2388
Query: 473 XXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+NE++ + ++ E + +++++++++E
Sbjct: 2389 TIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQE 2428
Score = 50.0 bits (114), Expect = 2e-05
Identities = 65/285 (22%), Positives = 124/285 (43%), Gaps = 34/285 (11%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD--- 313
I+ L+E T + ++E EN ++E+ +LN+K+ ++ E E +++ N LL D
Sbjct: 885 ISKLQE-DTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQE-LKKSNHLLEDSLK 942
Query: 314 ----------LSKK-----VNKTERELEEKQEQ---LTHLMEQLNDTENNSYKLIENMFN 355
L KK ++ +RE+EE ++ L + LN + N + E+ N
Sbjct: 943 ELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFAN 1002
Query: 356 -------KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINE-TQ 407
+S+++ +K + + +E+ N YE +S + L +NE T
Sbjct: 1003 YIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTS 1062
Query: 408 KNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS-NEEVTLNLKD 466
+N + E K+ Q + K L+ E N+ L++E++TV+ + E+T N +
Sbjct: 1063 LCENRKNELEQLKEAFAKEHQEFLTK--LAFAEERNQNLMLELETVQQALRSEMTDNQNN 1120
Query: 467 SSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
S + E M+ +V + + E L VMK + +
Sbjct: 1121 SKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHE 1165
Score = 49.2 bits (112), Expect = 3e-05
Identities = 86/416 (20%), Positives = 176/416 (42%), Gaps = 46/416 (11%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELE------ALKRENIQMHTSDVMVVPEIIDS-LTE 132
L E ++ E + N+L++L E A E + A E Q ++ V + + S +T+
Sbjct: 1057 LNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTD 1116
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISI----KTLLDKLITKNETDINE---LRN 185
N + L++ + + ++N + K+ + + L+ + TK+E E +RN
Sbjct: 1117 NQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRN 1176
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
S+K ES +++ N + E ++D N +++ + + N+ L
Sbjct: 1177 SVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAM-LRNKELKLQESEKEKECLQ 1235
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQ 305
D +NL++M++ +++S +K+ EID EK I E + +
Sbjct: 1236 HELQTIRGDLETSNLQDMQS----QEISGLKDC------EIDA-EEKYISGPHELSTSQN 1284
Query: 306 EKNILLSDLS---KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
+ L L K+N+ E+ E Q + L+ +LND+ + M +V ++ +
Sbjct: 1285 DNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEVGKLLN 1344
Query: 363 DFKISNQ----LSCELDD--------ESENTYERISLTLDKITNHITYLNTQINETQKND 410
+ KI N L EL + E N +SL +N +L E Q +
Sbjct: 1345 EVKILNDDSGLLHGELVEDIPGGEFGEQPNEQHPVSLAPLDESNSYEHLTLSDKEVQMH- 1403
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
E +++ L ++ IL ++ Q+ ++ EL + +++ N ++ NL++
Sbjct: 1404 ----FAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDSLKAENLVLSTNLRN 1455
Score = 45.2 bits (102), Expect = 6e-04
Identities = 52/264 (19%), Positives = 117/264 (44%), Gaps = 20/264 (7%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNE------TMQEKNILL 311
A+LE ++T EKL +++ +EN ++ I L E+L E N+ TM +K L
Sbjct: 1923 ADLEVVQT----EKLC-LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTAL 1977
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
LS+K+ + +ELE Q + H ++ +L++ + + VS++ D +
Sbjct: 1978 DQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKL 2037
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
L+ +S + +SLT ++ N I LN + E ++ L +A+ +D + N+
Sbjct: 2038 QSLEKDS----QALSLTKCELENQIAQLNKE-KELLVKESESL--QARLSESDYEKLNV- 2089
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
+ L E E + + + + ++ ++ + ++++ + +
Sbjct: 2090 -SKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERE 2148
Query: 492 VMEWKSQFEDLDDVMKQQQKELKL 515
K + E+L+ ++ ++ +L
Sbjct: 2149 NDSLKDKVENLERELQMSEENQEL 2172
Score = 43.2 bits (97), Expect = 0.002
Identities = 56/264 (21%), Positives = 111/264 (42%), Gaps = 15/264 (5%)
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL---ICDRREFNETMQEKNILLSDLS 315
+L+E++ M E E+++ K+E L+EKL CD +E + ++ L SDL
Sbjct: 1812 HLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLE 1871
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+K+ R E + + ++ND+ + +EN +++ + + L E D
Sbjct: 1872 MHADKSSR------EDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIE-HEALYLEAD 1924
Query: 376 DESENTYERISLTLDKITNH--ITYLNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNII 431
E T E++ L D I L +++ +++N L K+ L + +
Sbjct: 1925 LEVVQT-EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEK 1983
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
+KE+ +LE+ E L IQ +E T L+ S+ +++ ++
Sbjct: 1984 MKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKD 2043
Query: 492 VMEWKSQFEDLDDVMKQQQKELKL 515
+L++ + Q KE +L
Sbjct: 2044 SQALSLTKCELENQIAQLNKEKEL 2067
Score = 42.7 bits (96), Expect = 0.003
Identities = 87/485 (17%), Positives = 188/485 (38%), Gaps = 21/485 (4%)
Query: 35 QLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDL 94
Q + L+ G+ + K + + +R L LT +L + + ++L
Sbjct: 2352 QEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISEL 2411
Query: 95 KKLYEDSASELEALKRENIQMH--TSDVMVVPEI-IDSLTEVINTLTNGFESLEEVALEI 151
+ + + L+ ++E +QM +S M + + + L E + L N E+ + +
Sbjct: 2412 EIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNL 2471
Query: 152 DLKKNSITKDNISIKTLLDK-----LITKNETD--INELRNSIKYLESVKSEYNTANEKL 204
+ + + + LD+ ++ ++ + I E+ + + LE E + ++
Sbjct: 2472 SSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQI 2531
Query: 205 FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMK 264
+Q V K + ++ E L K +N L + + L+
Sbjct: 2532 QDQ-EQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSY 2590
Query: 265 TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L E +L K +F ++++ + K +RE +E Q+ L +LS + N+ E
Sbjct: 2591 KNL-ENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGE 2649
Query: 325 LEEKQEQLTHLMEQLND--TENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
L+ E++ +QL + EN+ K + +K Q+ + K+ +++ E
Sbjct: 2650 LQLLLEEIKSSKDQLKELTLENSELKKSLDCMHK-DQVEKEGKVREEIAEYQLRLHEAEK 2708
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
+ +L LD TN + Q + + L K +I DL + + KE L+
Sbjct: 2709 KHQALLLD--TNKQYEVEIQTYREKLTSKEECLSSQKLEI-DLLKSS---KEELNNSLKA 2762
Query: 443 NKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDL 502
++L E++ + N + LK + ++E+ K + + SQ +
Sbjct: 2763 TTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAA 2822
Query: 503 DDVMK 507
+ K
Sbjct: 2823 QEKQK 2827
Score = 37.1 bits (82), Expect = 0.15
Identities = 28/127 (22%), Positives = 62/127 (48%), Gaps = 16/127 (12%)
Query: 389 LDKITNHITYLNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++ + N + L+++++ E Q + E +K + +L ++N L E+L +++EL
Sbjct: 1797 VESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQEL 1856
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME-WKSQFEDLDDV 505
L ++T G N ++ ++ SS +I D KV + WK +F D+++
Sbjct: 1857 LQRVETSEGLNSDLEMHADKSS-------------REDIGDNVAKVNDSWKERFLDVENE 1903
Query: 506 MKQQQKE 512
+ + + E
Sbjct: 1904 LSRIRSE 1910
Score = 33.5 bits (73), Expect = 1.8
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 284 QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ-LNDT 342
+E++ L E + E M+ + I+ + K++ + E+ L ++++L L +Q L++
Sbjct: 1550 EELESLCEVYRQSLEKLEEKMESQGIMKN---KEIQELEQLLSSERQELDCLRKQYLSEN 1606
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
E KL S++A++ K + QLS EL+
Sbjct: 1607 EQWQQKLTSVTLEMESKLAAEKKQTEQLSLELE 1639
Score = 33.1 bits (72), Expect = 2.4
Identities = 37/196 (18%), Positives = 76/196 (38%), Gaps = 3/196 (1%)
Query: 325 LEEKQEQLTH-LMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
LE+K ++LT L Q + E+ L + + K + + + LD E
Sbjct: 360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Query: 384 RISLTLDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
R++ L + N L ++++ + K L E K+++ + + + ++L
Sbjct: 420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRR 479
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+E+ E ++ +E+ + N E+MK K ++ D
Sbjct: 480 SMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRD 539
Query: 502 LDDVMKQQQKELKLGK 517
L + + QQ+ L L K
Sbjct: 540 LQEKINQQENSLTLEK 555
Score = 31.5 bits (68), Expect = 7.4
Identities = 30/156 (19%), Positives = 66/156 (42%), Gaps = 6/156 (3%)
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
T + L L AV C +EV ++ +NL + + +
Sbjct: 1503 TGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAKGVEELESLC-EVYRQ 1561
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF---NETMQEK-NILLSDL 314
+LE+++ + + + + KE E +Q + ++L C R+++ NE Q+K + ++
Sbjct: 1562 SLEKLEEKMESQGIMKNKEIQE-LEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEM 1620
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLI 350
K+ +++ E+ +L QL + +S L+
Sbjct: 1621 ESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLL 1656
Score = 31.1 bits (67), Expect = 9.8
Identities = 20/93 (21%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+K+ + E +L++ +++ QL+ E K + + N+ ++ ++ K NQ E+
Sbjct: 18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTE-GTNLKRENQRLMEIC 76
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQK 408
+ E T ++IS L + + + Q+N +K
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKK 109
>AL445305-6|CAH73032.1| 3114|Homo sapiens centromere protein F,
350/400ka (mitosin) protein.
Length = 3114
Score = 55.6 bits (128), Expect = 4e-07
Identities = 98/522 (18%), Positives = 221/522 (42%), Gaps = 46/522 (8%)
Query: 8 LFANNENIRNIIHAFKIRLEECYKEI-GQLKSGLQQNVGVGDKTVAELKNDEINSMIRQL 66
L A N+ +RN I+ ++RL+ KE+ GQ+ + + + +K EL E ++ +
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQL-EKAKVELIEKE--KVLNKC 339
Query: 67 XXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEI 126
+ K T E K LKKL ED + + + + + + E
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQK---LKKLTEDLSCQRQNAESARCSLEQK----IKEK 392
Query: 127 IDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS 186
E ++ F++L++ +++ K +T++ K + + L + ++++L +
Sbjct: 393 EKEFQEELSRQQRSFQTLDQECIQM---KARLTQELQQAKNMHNVL----QAELDKLTSV 445
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
+ LE+ E+ + + + K+N ++ ++ +K EN NLL+
Sbjct: 446 KQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKEN-NLLKSHSEQKAREVCH 504
Query: 247 XXXXXARDKFIANLEEMKTMLVEEK--LSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
A L+ +K L + + E+K K+ + + + L EK+ +++E + T+
Sbjct: 505 LE---------AELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKI--NQQENSLTL 553
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
++ + ++DL K+ + ++ L++++ + L ++L+ TE S L+ + K +
Sbjct: 554 EKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEYEELK 613
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNT-----QINETQKNDNAQLLWEAK 419
+ SC E+E ++ + + + I +L T QI + N+ + L +
Sbjct: 614 EEKTLFSC-WKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDR 672
Query: 420 KQIA-DLTEQNIILKERLSQLETENKELL-----IEIQTVRGSNEEVTLNLKDSSTX--X 471
+ ++ ++ + +L + ++ET+ + E + E + LK S
Sbjct: 673 ENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQV 732
Query: 472 XXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
SNEI D + +++E L D++K + L
Sbjct: 733 EDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASL 774
Score = 52.0 bits (119), Expect = 5e-06
Identities = 101/520 (19%), Positives = 222/520 (42%), Gaps = 47/520 (9%)
Query: 11 NNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVA-ELKNDEINSMIRQLXXX 69
+NEN + +I + L E QL+ L + KT A + ++++ ++L
Sbjct: 1938 DNENKQKVIVCLEEELSVVTSERNQLRGELDT---MSKKTTALDQLSEKMKEKTQELESH 1994
Query: 70 XXX----XXXXXXXLTEKLTIAETKHNDLKKLYEDSA---SELEALKRENIQMHTSDVMV 122
+ EK + +T +D+ +L +D +L++L++++ + + +
Sbjct: 1995 QSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCEL 2054
Query: 123 VPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKD---NISIKTLLDKLITKNETD 179
+I L + L ESL+ E D +K +++K + K ++ + +
Sbjct: 2055 ENQIAQ-LNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEE 2113
Query: 180 INELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXX 239
+++LR I+ L V+ E A+EK +QL+ A +K + E D LK + +NL +
Sbjct: 2114 VHQLRRGIEKLR-VRIE---ADEK--KQLHIA-EKLKERERENDSLKDKVENLERELQMS 2166
Query: 240 XXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDRR 298
++ I + E K VE ++I+E + K E+D++ L ++
Sbjct: 2167 EEN----------QELVILDAENSKAE-VETLKTQIEEMARSLKVFELDLVT--LRSEKE 2213
Query: 299 EFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
+ +QEK LS+L K ++ + LEEK++ + E+ ++ + V+
Sbjct: 2214 NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVA 2273
Query: 359 QIASDFKISNQLSCELDDESE------NTYERISLTLDKITNHITYLNTQINETQKNDNA 412
+ D +I LD E N+ E++ L+ + Q+ E++ +A
Sbjct: 2274 ALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESE--HHA 2331
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
LL K ++ +L + I + E + E++T++ E +T +L+
Sbjct: 2332 DLL---KGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVV 2388
Query: 473 XXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+NE++ + ++ E + +++++++++E
Sbjct: 2389 TIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQE 2428
Score = 50.0 bits (114), Expect = 2e-05
Identities = 65/285 (22%), Positives = 124/285 (43%), Gaps = 34/285 (11%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD--- 313
I+ L+E T + ++E EN ++E+ +LN+K+ ++ E E +++ N LL D
Sbjct: 885 ISKLQE-DTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQE-LKKSNHLLEDSLK 942
Query: 314 ----------LSKK-----VNKTERELEEKQEQ---LTHLMEQLNDTENNSYKLIENMFN 355
L KK ++ +RE+EE ++ L + LN + N + E+ N
Sbjct: 943 ELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFAN 1002
Query: 356 -------KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINE-TQ 407
+S+++ +K + + +E+ N YE +S + L +NE T
Sbjct: 1003 YIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTS 1062
Query: 408 KNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS-NEEVTLNLKD 466
+N + E K+ Q + K L+ E N+ L++E++TV+ + E+T N +
Sbjct: 1063 LCENRKNELEQLKEAFAKEHQEFLTK--LAFAEERNQNLMLELETVQQALRSEMTDNQNN 1120
Query: 467 SSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
S + E M+ +V + + E L VMK + +
Sbjct: 1121 SKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHE 1165
Score = 49.2 bits (112), Expect = 3e-05
Identities = 86/416 (20%), Positives = 176/416 (42%), Gaps = 46/416 (11%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELE------ALKRENIQMHTSDVMVVPEIIDS-LTE 132
L E ++ E + N+L++L E A E + A E Q ++ V + + S +T+
Sbjct: 1057 LNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTD 1116
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISI----KTLLDKLITKNETDINE---LRN 185
N + L++ + + ++N + K+ + + L+ + TK+E E +RN
Sbjct: 1117 NQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRN 1176
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
S+K ES +++ N + E ++D N +++ + + N+ L
Sbjct: 1177 SVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAM-LRNKELKLQESEKEKECLQ 1235
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQ 305
D +NL++M++ +++S +K+ EID EK I E + +
Sbjct: 1236 HELQTIRGDLETSNLQDMQS----QEISGLKDC------EIDA-EEKYISGPHELSTSQN 1284
Query: 306 EKNILLSDLS---KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
+ L L K+N+ E+ E Q + L+ +LND+ + M +V ++ +
Sbjct: 1285 DNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEVGKLLN 1344
Query: 363 DFKISNQ----LSCELDD--------ESENTYERISLTLDKITNHITYLNTQINETQKND 410
+ KI N L EL + E N +SL +N +L E Q +
Sbjct: 1345 EVKILNDDSGLLHGELVEDIPGGEFGEQPNEQHPVSLAPLDESNSYEHLTLSDKEVQMH- 1403
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
E +++ L ++ IL ++ Q+ ++ EL + +++ N ++ NL++
Sbjct: 1404 ----FAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDSLKAENLVLSTNLRN 1455
Score = 45.2 bits (102), Expect = 6e-04
Identities = 52/264 (19%), Positives = 117/264 (44%), Gaps = 20/264 (7%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNE------TMQEKNILL 311
A+LE ++T EKL +++ +EN ++ I L E+L E N+ TM +K L
Sbjct: 1923 ADLEVVQT----EKLC-LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTAL 1977
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
LS+K+ + +ELE Q + H ++ +L++ + + VS++ D +
Sbjct: 1978 DQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKL 2037
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
L+ +S + +SLT ++ N I LN + E ++ L +A+ +D + N+
Sbjct: 2038 QSLEKDS----QALSLTKCELENQIAQLNKE-KELLVKESESL--QARLSESDYEKLNV- 2089
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
+ L E E + + + + ++ ++ + ++++ + +
Sbjct: 2090 -SKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERE 2148
Query: 492 VMEWKSQFEDLDDVMKQQQKELKL 515
K + E+L+ ++ ++ +L
Sbjct: 2149 NDSLKDKVENLERELQMSEENQEL 2172
Score = 43.2 bits (97), Expect = 0.002
Identities = 56/264 (21%), Positives = 111/264 (42%), Gaps = 15/264 (5%)
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL---ICDRREFNETMQEKNILLSDLS 315
+L+E++ M E E+++ K+E L+EKL CD +E + ++ L SDL
Sbjct: 1812 HLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLE 1871
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+K+ R E + + ++ND+ + +EN +++ + + L E D
Sbjct: 1872 MHADKSSR------EDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIE-HEALYLEAD 1924
Query: 376 DESENTYERISLTLDKITNH--ITYLNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNII 431
E T E++ L D I L +++ +++N L K+ L + +
Sbjct: 1925 LEVVQT-EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEK 1983
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
+KE+ +LE+ E L IQ +E T L+ S+ +++ ++
Sbjct: 1984 MKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKD 2043
Query: 492 VMEWKSQFEDLDDVMKQQQKELKL 515
+L++ + Q KE +L
Sbjct: 2044 SQALSLTKCELENQIAQLNKEKEL 2067
Score = 42.7 bits (96), Expect = 0.003
Identities = 87/485 (17%), Positives = 188/485 (38%), Gaps = 21/485 (4%)
Query: 35 QLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDL 94
Q + L+ G+ + K + + +R L LT +L + + ++L
Sbjct: 2352 QEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISEL 2411
Query: 95 KKLYEDSASELEALKRENIQMH--TSDVMVVPEI-IDSLTEVINTLTNGFESLEEVALEI 151
+ + + L+ ++E +QM +S M + + + L E + L N E+ + +
Sbjct: 2412 EIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNL 2471
Query: 152 DLKKNSITKDNISIKTLLDK-----LITKNETD--INELRNSIKYLESVKSEYNTANEKL 204
+ + + + LD+ ++ ++ + I E+ + + LE E + ++
Sbjct: 2472 SSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQI 2531
Query: 205 FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMK 264
+Q V K + ++ E L K +N L + + L+
Sbjct: 2532 QDQ-EQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSY 2590
Query: 265 TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L E +L K +F ++++ + K +RE +E Q+ L +LS + N+ E
Sbjct: 2591 KNL-ENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGE 2649
Query: 325 LEEKQEQLTHLMEQLND--TENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
L+ E++ +QL + EN+ K + +K Q+ + K+ +++ E
Sbjct: 2650 LQLLLEEIKSSKDQLKELTLENSELKKSLDCMHK-DQVEKEGKVREEIAEYQLRLHEAEK 2708
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
+ +L LD TN + Q + + L K +I DL + + KE L+
Sbjct: 2709 KHQALLLD--TNKQYEVEIQTYREKLTSKEECLSSQKLEI-DLLKSS---KEELNNSLKA 2762
Query: 443 NKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDL 502
++L E++ + N + LK + ++E+ K + + SQ +
Sbjct: 2763 TTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAA 2822
Query: 503 DDVMK 507
+ K
Sbjct: 2823 QEKQK 2827
Score = 37.1 bits (82), Expect = 0.15
Identities = 28/127 (22%), Positives = 62/127 (48%), Gaps = 16/127 (12%)
Query: 389 LDKITNHITYLNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++ + N + L+++++ E Q + E +K + +L ++N L E+L +++EL
Sbjct: 1797 VESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQEL 1856
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME-WKSQFEDLDDV 505
L ++T G N ++ ++ SS +I D KV + WK +F D+++
Sbjct: 1857 LQRVETSEGLNSDLEMHADKSS-------------REDIGDNVAKVNDSWKERFLDVENE 1903
Query: 506 MKQQQKE 512
+ + + E
Sbjct: 1904 LSRIRSE 1910
Score = 33.5 bits (73), Expect = 1.8
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 284 QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ-LNDT 342
+E++ L E + E M+ + I+ + K++ + E+ L ++++L L +Q L++
Sbjct: 1550 EELESLCEVYRQSLEKLEEKMESQGIMKN---KEIQELEQLLSSERQELDCLRKQYLSEN 1606
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
E KL S++A++ K + QLS EL+
Sbjct: 1607 EQWQQKLTSVTLEMESKLAAEKKQTEQLSLELE 1639
Score = 33.1 bits (72), Expect = 2.4
Identities = 37/196 (18%), Positives = 76/196 (38%), Gaps = 3/196 (1%)
Query: 325 LEEKQEQLTH-LMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
LE+K ++LT L Q + E+ L + + K + + + LD E
Sbjct: 360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Query: 384 RISLTLDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
R++ L + N L ++++ + K L E K+++ + + + ++L
Sbjct: 420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRR 479
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+E+ E ++ +E+ + N E+MK K ++ D
Sbjct: 480 SMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRD 539
Query: 502 LDDVMKQQQKELKLGK 517
L + + QQ+ L L K
Sbjct: 540 LQEKINQQENSLTLEK 555
Score = 31.5 bits (68), Expect = 7.4
Identities = 30/156 (19%), Positives = 66/156 (42%), Gaps = 6/156 (3%)
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
T + L L AV C +EV ++ +NL + + +
Sbjct: 1503 TGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAKGVEELESLC-EVYRQ 1561
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF---NETMQEK-NILLSDL 314
+LE+++ + + + + KE E +Q + ++L C R+++ NE Q+K + ++
Sbjct: 1562 SLEKLEEKMESQGIMKNKEIQE-LEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEM 1620
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLI 350
K+ +++ E+ +L QL + +S L+
Sbjct: 1621 ESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLL 1656
Score = 31.1 bits (67), Expect = 9.8
Identities = 20/93 (21%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+K+ + E +L++ +++ QL+ E K + + N+ ++ ++ K NQ E+
Sbjct: 18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAALQKQKQKVENEKTE-GTNLKRENQRLMEIC 76
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQK 408
+ E T ++IS L + + + Q+N +K
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKK 109
>AB125644-1|BAF44475.1| 1843|Homo sapiens PKB/Akt-binding protein
protein.
Length = 1843
Score = 55.6 bits (128), Expect = 4e-07
Identities = 93/450 (20%), Positives = 188/450 (41%), Gaps = 38/450 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMV--VPEIIDSLTEVINTLTN 139
E+L I+ + L+K + E L+++ Q+ + + EI D+ E N
Sbjct: 801 EELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIG 860
Query: 140 GFESLEE-VALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYN 198
E + ++ EI + K S + L +L +N+ + IK L +++ +
Sbjct: 861 NLEKENKTLSKEIGIYKESCVR--------LKELEKENKELVKRATIDIKTLVTLREDL- 911
Query: 199 TANEKL-FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD-KF 256
+EKL +Q+NN ++K + E++ + + + LL K
Sbjct: 912 -VSEKLKTQQMNNDLEK---LTHELEKIGLNKERLLHDEQSTDDSRYKLLESKLESTLKK 967
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL-ICDRREFNETMQEKNILLSDLS 315
++E K +E +L E ++ +QE+ + + +R+ E M + + +S
Sbjct: 968 SLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSS---PPIS 1024
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+ NK ERE +E +L + ++L + E N+ L +Q+ +N L ++
Sbjct: 1025 GEDNKWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL 1084
Query: 376 DESENTY--ERISLTLDKITNHITYLNTQINETQK---NDNAQLLWEAKKQIADLTEQNI 430
T + + TL + N+ +N N NAQLL + Q + E
Sbjct: 1085 ALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQSTSLMNQNAQLLIQ---QSSLENENES 1141
Query: 431 ILKERLSQLETENKELL-----IEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEI 485
++KER L++ L+ +E+ R ++E +L K + ++
Sbjct: 1142 VIKER-EDLKSLYDSLIKDHEKLELLHERQASEYESLISKHGTLKSAHKNLEVEH--RDL 1198
Query: 486 EDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
ED ++++ K Q EDL+ ++K +Q+++ L
Sbjct: 1199 EDRYNQLLKQKGQLEDLEKMLKVEQEKMLL 1228
Score = 52.4 bits (120), Expect = 4e-06
Identities = 89/436 (20%), Positives = 200/436 (45%), Gaps = 55/436 (12%)
Query: 53 ELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIA----ETKHNDLKKLYEDSASELEAL 108
+L+N E+ S QL TE+L ++ + ++ L+K E+S +++ L
Sbjct: 724 QLENKELESEKEQLKKGLELLKASFKK-TERLEVSYQGLDIENQRLQKTLENSNKKIQQL 782
Query: 109 KRE--NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIK 166
+ E +++M + E + ++ + L +SLE+ +++ K + K+N K
Sbjct: 783 ESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQLEKEN---K 839
Query: 167 TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLK 226
L + K +T + E N++K + +++ E T ++++ + K++C++ + L+
Sbjct: 840 RLRQQAEIK-DTTLEE--NNVK-IGNLEKENKTLSKEI------GIYKESCVR--LKELE 887
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEI 286
EN+ L++ R+ ++ E++KT + L ++ + E +I
Sbjct: 888 KENKELVKRATIDIKTLVTL------REDLVS--EKLKTQQMNNDLEKLTHELE----KI 935
Query: 287 DMLNEKLICDRREFNETMQE--KNILLSDLSKKVNKTERE---LEEKQEQLTHLMEQLND 341
+ E+L+ D + +++ + ++ L S L K + E + LE + E+ T+ +QL
Sbjct: 936 GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQ 995
Query: 342 ---TENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKIT----N 394
T +Y+ ++ ++ + S IS + + + + ES+ T + D++ N
Sbjct: 996 ELKTVKKNYEALKQRQDEERMVQSSPPISGEDN-KWERESQETTRELLKVKDRLIEVERN 1054
Query: 395 HITY------LNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
+ T L TQ+ ETQ N+ + ++Q L EQN L+ + ++L+ EN L
Sbjct: 1055 NATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 1114
Query: 447 LIEIQTVRGSNEEVTL 462
+ ++ N ++ +
Sbjct: 1115 NSQSTSLMNQNAQLLI 1130
Score = 51.6 bits (118), Expect = 6e-06
Identities = 108/502 (21%), Positives = 204/502 (40%), Gaps = 38/502 (7%)
Query: 24 IRLEECYKEIGQLKS----GLQQNVGVGDKTVAE-LKNDEINSMIRQLXXXXXXXXXXXX 78
+RL+E KE +L ++ V + + V+E LK ++N+ + +L
Sbjct: 881 VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKE 940
Query: 79 XLT-EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTL 137
L ++ + ++++ L+ E + + +K E I + + L + + T+
Sbjct: 941 RLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTV 1000
Query: 138 TNGFESLEEVALEIDLKKNSIT---KDNI----SIKTLLDKLITKNETDINELRNSIKYL 190
+E+L++ E + ++S +DN S +T + L K+ + E+ + L
Sbjct: 1001 KKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDR--LIEVERNNATL 1058
Query: 191 ESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXX 250
++ K T ++L Q NN + +Q + L+ +N L
Sbjct: 1059 QAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQS 1118
Query: 251 XARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDML---NEKL-ICDRREFNE--TM 304
+ A L ++ L E S IKE+ E+ K D L +EKL + R+ +E ++
Sbjct: 1119 TSLMNQNAQLLIQQSSLENENESVIKER-EDLKSLYDSLIKDHEKLELLHERQASEYESL 1177
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF--NKVSQ-IA 361
K+ L K + R+LE++ QL QL D E E M NK + +A
Sbjct: 1178 ISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVA 1237
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKI-TNHITYL----NTQINETQKNDNAQLLW 416
+++K C +D +TY ++ + + T+H N+++ +T+ L
Sbjct: 1238 AEYK----KLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLK 1293
Query: 417 EAKKQI----ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
E +Q+ L Q +L + LE EN+ LL +IQT+ N + +S
Sbjct: 1294 EQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFH 1353
Query: 473 XXXXXXXXXSNEIEDMKTKVME 494
NE+ K K+ E
Sbjct: 1354 VEQRQYIDKLNELRRQKEKLEE 1375
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
E+ Q ++ L+D K+ + +ELEEK EQL ++L E +L + N +S
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 303
Query: 362 SDFKISNQLSC--ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
S ++L E + +S +++ + I + ++ E K DN Q+L E K
Sbjct: 304 SARMYRDELDALREKAVRVDKLESEVSRYKERL-HDIEFYKARVEEL-KEDN-QVLLETK 360
Query: 420 KQIADLTEQNIILKERLSQLETENKEL 446
+ D E ++L +LE EN +L
Sbjct: 361 TMLEDQLEGTRARSDKLHELEKENLQL 387
Score = 49.6 bits (113), Expect = 3e-05
Identities = 77/429 (17%), Positives = 182/429 (42%), Gaps = 26/429 (6%)
Query: 99 EDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
E +AS++ +++EN ++ ++ EI+ + N + ++E A L+K
Sbjct: 487 EGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA---QLEKTIE 543
Query: 159 TKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTA-----NEKLFEQLNNAVD 213
T S + + K++ + +N+ +S++ + +E N+ L E +
Sbjct: 544 TLRENSERQI--KILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSS 601
Query: 214 KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLS 273
K + I+ E +K E ++ + + + +K + EK+
Sbjct: 602 KLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLK--ITCEKIE 659
Query: 274 EIKEKDENFKQEIDMLNEKLICDRR-EFN-ETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
+++++ ++E L + L + F E+++++N L + + ++ + L+ +
Sbjct: 660 ALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMK 719
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD-ESENTYERISLTLD 390
+ L QL + E S K E + + + + FK + +L + EN +R+ TL+
Sbjct: 720 MAQL--QLENKELESEK--EQLKKGLELLKASFKKTERLEVSYQGLDIEN--QRLQKTLE 773
Query: 391 KITNHITYLNTQINETQKND-----NAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
I L +++ + + + N + L + K++ L ++N L++ SQLE + K+
Sbjct: 774 NSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 833
Query: 446 LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDV 505
L E + +R E L++++ S EI K + K ++ ++
Sbjct: 834 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLKELEKENKEL 893
Query: 506 MKQQQKELK 514
+K+ ++K
Sbjct: 894 VKRATIDIK 902
Score = 35.1 bits (77), Expect = 0.60
Identities = 83/452 (18%), Positives = 176/452 (38%), Gaps = 30/452 (6%)
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
+ + + D++ L ++ A L+ L E + H+ ++ + E D L + + ++
Sbjct: 176 MEVTDMSQEDIEPLLKNMALHLKRLIDERDE-HSETIIELSEERDGLHFLPHASSSAQSP 234
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
++ + ++ + K + +L + E +L + + LE ++ E ++
Sbjct: 235 CGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE 294
Query: 204 LFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN-- 259
L++A + ++E+D L K + L+ AR + +
Sbjct: 295 NMNLLSDARSAR-MYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDN 353
Query: 260 --LEEMKTMLVEE---------KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
L E KTML ++ KL E+++++ K ++ + + DR++ E M+E N
Sbjct: 354 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE-N 412
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN 368
+ L K+ L + EQ++ E L++ S L + S ++ N
Sbjct: 413 MTLEMAQKQSMDESLHLGWELEQISRTSE-LSEAPQKS--LGHEVNELTSSRLLKLEMEN 469
Query: 369 QLSCELDDESENTYERISLTLDKI-----TNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
Q + +E T + + KI N +I E + Q L +
Sbjct: 470 QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 529
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL-NLKDSSTXXXXXXXXXXXXS 482
DL ++ L++ + L EN E I+I + T+ +L+ S
Sbjct: 530 DLMKEKAQLEKTIETLR-ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE 588
Query: 483 NEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
N+I + + E S+ ++ +Q +KEL+
Sbjct: 589 NKI--LHESIKETSSKLSKIEFEKRQIKKELE 618
>D86958-1|BAA13194.2| 1593|Homo sapiens KIAA0203 protein.
Length = 1593
Score = 55.2 bits (127), Expect = 5e-07
Identities = 70/381 (18%), Positives = 168/381 (44%), Gaps = 30/381 (7%)
Query: 146 EVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS-----IKYLESVKSEYNTA 200
E+ LE DLKK + D ++ L +L + ++ + EL ++ I+ E V +++ +
Sbjct: 958 EIVLE-DLKKLHVENDE-KLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVS 1015
Query: 201 NEKLF---EQLNNAVDKQNC--IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
E+L +Q+ N + + + IQE+ L+ + D+
Sbjct: 1016 LEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDE 1075
Query: 256 FIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS-DL 314
LEE + E S ++++ EN + EI LN+K+ + + + E L++ +
Sbjct: 1076 IKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEK 1135
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ +++ EE+ L + ++ N ++++ +N+ ++ ++ S K+ ++LS L
Sbjct: 1136 DQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQS--KLDSELSA-L 1192
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ + + + + I ++ ++ +Q+ D QL+ + + E
Sbjct: 1193 ERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQK-------------LNCE 1239
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
+ ++T KE +E + V E +L++ S+ + +++ K+ E
Sbjct: 1240 KDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQE 1299
Query: 495 WKSQF-EDLDDVMKQQQKELK 514
K++F E L++ K++ +E++
Sbjct: 1300 EKAKFLEQLEEQEKRKNEEMQ 1320
>BC131805-1|AAI31806.1| 913|Homo sapiens CCDC46 protein protein.
Length = 913
Score = 55.2 bits (127), Expect = 5e-07
Identities = 93/499 (18%), Positives = 208/499 (41%), Gaps = 41/499 (8%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLT 85
LE EI +LK+ + ++T+ +L+ ++ ++IR L +
Sbjct: 245 LERKNNEIEELKTLYRSKQHETEETIRKLEK-KVQTLIRDCQVIRETKEDQIAELKKICE 303
Query: 86 IA-ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF--- 141
+ E+ +ND +K ++ +E+E K + + HT ++ E+++ +N + + +
Sbjct: 304 QSTESLNNDWEKKLHNAVAEMEQEKFDLQKQHTENIQ---ELLEDTNVRLNKMESEYMAQ 360
Query: 142 -ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTA 200
+S + E++ + +T + + KLI + + + L+ VK+ NT
Sbjct: 361 TQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELERCYQITCSELQEVKARRNTL 420
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
+++ +N+ +Q + D + NLL+ ++ N+
Sbjct: 421 HKEKDHLVNDYEQNMKLLQTKYDA----DINLLKQEHALSASKASSMI-----EELEQNV 471
Query: 261 EEMKTMLVEEKLSEIKE-KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
++K L E +L ++ +D+ K +++ + K I + + ++ E + D KK++
Sbjct: 472 CQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYEEKA-HDLQSELDKGKEDTQKKIH 530
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE 379
K E L+EK+EQLT + E + +E F + ++ S+ K+ ++ E ++ E
Sbjct: 531 KFEEALKEKEEQLTRVTEVQRLQAQQADAALEE-FKRQVELNSE-KVYAEMK-EQMEKVE 587
Query: 380 NTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERL--- 436
R +K + + I + + +L E +++ L +Q+ K+ L
Sbjct: 588 ADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVELKLEHEQEKTHLLQQHNAEKDSLVRD 647
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWK 496
+ E EN E + + N+ +D+ I DM+ +V + +
Sbjct: 648 HEREIENLEKQLRAANMEHENQIQEFKKRDAQV---------------IADMEAQVHKLR 692
Query: 497 SQFEDLDDVMKQQQKELKL 515
+ +++ KQQ EL L
Sbjct: 693 EELINVNSQRKQQLVELGL 711
Score = 49.6 bits (113), Expect = 3e-05
Identities = 84/416 (20%), Positives = 170/416 (40%), Gaps = 53/416 (12%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
EKL + + D++K+ E +E+E LK ++ S E I L + + TL
Sbjct: 229 EKLKLQQKHDADVQKILERKNNEIEELK----TLYRSKQHETEETIRKLEKKVQTLIRDC 284
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETD-INELRNSIKYLESVK---SEY 197
+ + E K++ I + +K + ++ D +L N++ +E K +
Sbjct: 285 QVIRET------KEDQIAE----LKKICEQSTESLNNDWEKKLHNAVAEMEQEKFDLQKQ 334
Query: 198 NTAN-EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
+T N ++L E N ++K E + + N + + R K
Sbjct: 335 HTENIQELLEDTNVRLNKME--SEYMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQKL 392
Query: 257 IANLEEMKT--MLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK-----NI 309
I E++ + +L E+K + +E D L+ D + + +Q K N+
Sbjct: 393 IQEKAELERCYQITCSELQEVKARRNTLHKEKD----HLVNDYEQNMKLLQTKYDADINL 448
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK---- 365
L + + +K +EE ++ + L +QL ++E + + + NK S K
Sbjct: 449 LKQEHALSASKASSMIEELEQNVCQLKQQLQESELQRKQQLRDQENKFQMEKSHLKHIYE 508
Query: 366 -ISNQLSCELDDESENTYERISLTLDKITNHITYLN--TQINETQKNDNAQLLWEAKKQI 422
++ L ELD E+T ++I + + L T++ Q L E K+Q+
Sbjct: 509 EKAHDLQSELDKGKEDTQKKIHKFEEALKEKEEQLTRVTEVQRLQAQQADAALEEFKRQV 568
Query: 423 ADLTEQNII--LKERLSQLET-----------ENKELLIEIQTVRGSNEEVTLNLK 465
+L + + +KE++ ++E ++KE L +++ +R E+ + LK
Sbjct: 569 -ELNSEKVYAEMKEQMEKVEADLTRSKSLREKQSKEFLWQLEDIRQRYEQQIVELK 623
Score = 34.7 bits (76), Expect = 0.80
Identities = 51/270 (18%), Positives = 115/270 (42%), Gaps = 17/270 (6%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
A E K L ++ +++++ E EI+ L + E ET+++ + L +
Sbjct: 224 AKFHEEKLKLQQKHDADVQKILERKNNEIEELKTLYRSKQHETEETIRKLEKKVQTLIRD 283
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQLSCELDD 376
E++ +L + EQ ++ NN ++ + + N V+++ + F + Q + + +
Sbjct: 284 CQVIRETKEDQIAELKKICEQSTESLNNDWE--KKLHNAVAEMEQEKFDLQKQHTENIQE 341
Query: 377 ESENTYERIS------LTLDKITNH-ITYLNTQINE-TQKNDNAQLLWEAK-KQIADLTE 427
E+T R++ + + TNH I L ++ + T + +N+ L + ++ A+L
Sbjct: 342 LLEDTNVRLNKMESEYMAQTQSTNHMIKELEARVQQLTGEAENSNLQRQKLIQEKAELER 401
Query: 428 QNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK-----DSSTXXXXXXXXXXXXS 482
I L +++ L E + E+ L+ D + S
Sbjct: 402 CYQITCSELQEVKARRNTLHKEKDHLVNDYEQNMKLLQTKYDADINLLKQEHALSASKAS 461
Query: 483 NEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+ IE+++ V + K Q ++ + KQQ ++
Sbjct: 462 SMIEELEQNVCQLKQQLQESELQRKQQLRD 491
>BC017556-1|AAH17556.1| 1594|Homo sapiens RB1-inducible coiled-coil 1
protein.
Length = 1594
Score = 55.2 bits (127), Expect = 5e-07
Identities = 70/381 (18%), Positives = 168/381 (44%), Gaps = 30/381 (7%)
Query: 146 EVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS-----IKYLESVKSEYNTA 200
E+ LE DLKK + D ++ L +L + ++ + EL ++ I+ E V +++ +
Sbjct: 956 EIVLE-DLKKLHVENDE-KLQLLRAELQSLEQSHLKELEDTLQVRHIQEFEKVMTDHRVS 1013
Query: 201 NEKLF---EQLNNAVDKQNC--IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
E+L +Q+ N + + + IQE+ L+ + D+
Sbjct: 1014 LEELKKENQQIINQIQESHAEIIQEKEKQLQELKLKVSDLSDTRCKLEVELALKEAETDE 1073
Query: 256 FIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS-DL 314
LEE + E S ++++ EN + EI LN+K+ + + + E L++ +
Sbjct: 1074 IKILLEESRAQQKETLKSLLEQETENLRTEISKLNQKIQDNNENYQVGLAELRTLMTIEK 1133
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ +++ EE+ L + ++ N ++++ +N+ ++ ++ S K+ ++LS L
Sbjct: 1134 DQCISELISRHEEESNILKAELNKVTSLHNQAFEIEKNLKEQIIELQS--KLDSELSA-L 1190
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ + + + + I ++ ++ +Q+ D QL+ + + E
Sbjct: 1191 ERQKDEKITQQEEKYEAIIQNLEKDRQKLVSSQEQDREQLIQK-------------LNCE 1237
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
+ ++T KE +E + V E +L++ S+ + +++ K+ E
Sbjct: 1238 KDEAIQTALKEFKLEREVVEKELLEKVKHLENQIAKSPAIDSTRGDSSSLVAELQEKLQE 1297
Query: 495 WKSQF-EDLDDVMKQQQKELK 514
K++F E L++ K++ +E++
Sbjct: 1298 EKAKFLEQLEEQEKRKNEEMQ 1318
>AF111783-1|AAD29949.1| 1939|Homo sapiens myosin heavy chain IIb
protein.
Length = 1939
Score = 55.2 bits (127), Expect = 5e-07
Identities = 84/446 (18%), Positives = 172/446 (38%), Gaps = 21/446 (4%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L EK+ + NDL+ + A L + D ++ +I L I +T
Sbjct: 877 LEEKMVTLMQEKNDLQLQVQAEADALADAEER------CDQLIKTKI--QLEAKIKEVTE 928
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYLESVKSE 196
E EE+ E+ KK + + +K +D L + K E + + N +K L +
Sbjct: 929 RAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 988
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
+ KL ++ + +++ + + + L + K
Sbjct: 989 LDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLEQEKKL 1048
Query: 257 IANLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
+LE K L + KL++ D EN KQ+++ +K + ++++ L L
Sbjct: 1049 CMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIEDEQALAMQL 1108
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
KK+ + + +EE +E++ E L + ++S+ + + EL
Sbjct: 1109 QKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL-EEISERLEEAGGATSAQIEL 1167
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ + E ++++ L++ T + + T +K +A + E KQI L L++
Sbjct: 1168 NKKREAEFQKMRRDLEEST--LQHEATAAALRKK--HADSVAELGKQIDSLQRVKQKLEK 1223
Query: 435 RLSQLETENKELLIEIQTV---RGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
S+L+ E +L ++TV + + E++ L+D + NE+ K +
Sbjct: 1224 EKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQRLINELSAQKAR 1283
Query: 492 VMEWKSQFEDLDDVMKQQQKELKLGK 517
+ +F D +L GK
Sbjct: 1284 LHTESGEFSRQLDEKDAMVSQLSRGK 1309
Score = 52.0 bits (119), Expect = 5e-06
Identities = 81/427 (18%), Positives = 175/427 (40%), Gaps = 39/427 (9%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSD----VMVVPEIIDSLTEVINTLTNGFE----S 143
+K YE+S LE LKRE N+Q SD + + I L +V L + S
Sbjct: 1488 VKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTS 1547
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLDKLITKNETDINEL-RNSIKYLESVKSEYNT 199
LEE ++ ++ I + + +K+ +D+ I + + ++++L RN ++ +ES++S +
Sbjct: 1548 LEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDA 1607
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
+ L + + E L N+ + D I
Sbjct: 1608 EIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRG 1667
Query: 260 LEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K L VE + + ++ + E + ++ +E + + +L + +
Sbjct: 1668 QDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSL 1727
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE 377
+N T+++LE Q+ ME + N+ + + + +A + K S L
Sbjct: 1728 IN-TKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL--- 1783
Query: 378 SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS 437
ER+ +++ + L ++ E ++ L KKQI L + ++E S
Sbjct: 1784 -----ERMKKNMEQT---VKDLQLRLGEAEQ----LALKGGKKQIQKLEAR---VRELES 1828
Query: 438 QLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKS 497
++E+E K ++ V+G + +K+ + + ++ ++TKV +K
Sbjct: 1829 EVESEQKH---NVEAVKGLRKH-ERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKR 1884
Query: 498 QFEDLDD 504
Q E+ ++
Sbjct: 1885 QAEEAEE 1891
Score = 51.6 bits (118), Expect = 6e-06
Identities = 42/197 (21%), Positives = 94/197 (47%), Gaps = 9/197 (4%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDL 314
AN E+M L E++LSEIK K+E ++ I+ L+ +L + EF+ + EK+ ++S L
Sbjct: 1247 ANFEKMCRTL-EDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQLDEKDAMVSQL 1305
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
S+ +++EE + QL E+ ++ +++ + + ++ + EL
Sbjct: 1306 SRGKQAFTQQIEELKRQL----EEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAEL 1361
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
++ K ++ E +K AQ L +A++ + + + L++
Sbjct: 1362 QRGMSKANSEVAQWRTKYETDAIQRTEELEEAKKK-LAQRLQDAEEHVEAVNSKCASLEK 1420
Query: 435 RLSQLETENKELLIEIQ 451
+L+ E ++L+I+++
Sbjct: 1421 TKQRLQNEVEDLMIDVE 1437
Score = 49.6 bits (113), Expect = 3e-05
Identities = 51/264 (19%), Positives = 111/264 (42%), Gaps = 19/264 (7%)
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL---LSDLSKKVNKTERELE 326
+ L +K +++N +QEI L E++ + +E + K L S+L + + E LE
Sbjct: 1497 DHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLE 1556
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQLSCELDDE--SENTYE 383
++ ++ + +LN ++ + I ++ Q+ + ++ + LD E S N
Sbjct: 1557 HEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDAL 1616
Query: 384 RISLTLDKITNH----ITYLNTQINETQKN---------DNAQLLWEAKKQIADLTEQNI 430
RI ++ N + + N Q E +N D L +A + DL EQ
Sbjct: 1617 RIKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAIRGQDDLKEQLA 1676
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKT 490
+++ R + ++ E +EL ++ + L D+S N + ++T
Sbjct: 1677 MVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLET 1736
Query: 491 KVMEWKSQFEDLDDVMKQQQKELK 514
+ + + + ED+ + +++ K
Sbjct: 1737 DISQIQGEMEDIVQEARNAEEKAK 1760
Score = 38.7 bits (86), Expect = 0.049
Identities = 34/204 (16%), Positives = 92/204 (45%), Gaps = 3/204 (1%)
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+++ KTE + +E +E++ LM++ ND + + + + + K QL ++
Sbjct: 865 EELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKIQLEAKIK 924
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAKKQIADLTEQNI-ILK 433
+ +E + + + +T L + +E +K+ D+ +L ++ TE + L
Sbjct: 925 EVTERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 983
Query: 434 ERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
E ++ L+ +L E + ++ ++++ +L+ +++D++ +
Sbjct: 984 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLEQQVDDLEGSLE 1043
Query: 494 EWKSQFEDLDDVMKQQQKELKLGK 517
+ K DL+ ++ + +LKL +
Sbjct: 1044 QEKKLCMDLERAKRKLEGDLKLAQ 1067
Score = 32.7 bits (71), Expect = 3.2
Identities = 41/205 (20%), Positives = 92/205 (44%), Gaps = 12/205 (5%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
K +TE+E+ +E+ E+L TE +L E M + Q +D ++ Q +
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVT-LMQEKNDLQLQVQAEADALA 903
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKK---QIADLTEQNIILK 433
++E +++ T ++ I + T+ E ++ NA+L + +K + ++L + L+
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEV-TERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 434 ERLSQLE-----TEN--KELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIE 486
L+++E TEN K L E+ + + ++T K +++
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVN 1022
Query: 487 DMKTKVMEWKSQFEDLDDVMKQQQK 511
+ + + Q +DL+ ++Q++K
Sbjct: 1023 TLTKAKTKLEQQVDDLEGSLEQEKK 1047
>M69181-1|AAA99177.1| 1976|Homo sapiens non-muscle myosin B protein.
Length = 1976
Score = 54.8 bits (126), Expect = 7e-07
Identities = 78/440 (17%), Positives = 181/440 (41%), Gaps = 29/440 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K +E K ++++ +++L L EK + + + +++ L E++ +
Sbjct: 1247 KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKF 1306
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNISIK 166
++ + S + E++ T L++ LEE +L+ ++ + N+ +
Sbjct: 1307 AKDAASLE-SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ 1365
Query: 167 TL-LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNCI 218
L L + + +++ +I+ LE K + E L ++L A DK +N +
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 219 QEEVDLLKIENQNLLQXXXXX-----------XXXXXXXXXXXXARDKFIANLEEMKTML 267
Q+E+D L ++ + Q RD+ A E +T
Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA 1485
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEE 327
+ L+ E+ K+E + N++L D + + + + +L K E+++EE
Sbjct: 1486 LS--LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEE 1543
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
+ QL L ++L TE+ +L NM +Q D + ++ + +++ +++
Sbjct: 1544 MRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE---QNEEKKRLLIKQVRE 1600
Query: 388 TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
++ + + +K + EA+ + A+ +I ++L +L+ + K+
Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVI--KQLRKLQAQMKDYQ 1658
Query: 448 IEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K+S
Sbjct: 1659 RELEEARASRDEIFAQSKES 1678
Score = 46.4 bits (105), Expect = 2e-04
Identities = 95/513 (18%), Positives = 193/513 (37%), Gaps = 34/513 (6%)
Query: 14 NIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXX 73
++++ I + +++E ++ + + LQ + GD KN+ + ++R+L
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLH-KNNALK-VVRELQAQIAEL 1123
Query: 74 XXXXXXLTEKLTIAETKHNDLKKLYEDSASELE------ALKRENIQMHTSDVMVVPEII 127
AE + DL + E +ELE A ++E +V + + +
Sbjct: 1124 QEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAL 1183
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+ T+ ALE +L + + K L+K ETD EL +
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALE-ELSEQ--LEQAKRFKANLEKNKQGLETDNKELACEV 1240
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
K L+ VK+E +KL Q V + + E D L++E
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQ----VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLL 1296
Query: 248 XXXXARD-KFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
+ KF + +++ L +E L E + N I L E ++ E
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEE----EKNSLQEQQ 1352
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+E+ +L K+V + +L + ++++ + + E KL+++ +SQ +
Sbjct: 1353 EEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDA-EALSQRLEEK 1411
Query: 365 KISNQLSCELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDNAQLLWEAKKQ 421
++ D+ E T R+ LD +T +H + + + + QK + QLL E K
Sbjct: 1412 ALAY-------DKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFD-QLLAEEKSI 1463
Query: 422 IADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXX 481
A E+ + + ET+ L ++ + EE K
Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523
Query: 482 SNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ +++ + Q E++ +++ + EL+
Sbjct: 1524 GKNVHELEKSKRALEQQVEEMRTQLEELEDELQ 1556
Score = 45.2 bits (102), Expect = 6e-04
Identities = 69/352 (19%), Positives = 142/352 (40%), Gaps = 17/352 (4%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
L K+ K E I++L +K E + E A KL + + D+ +Q ++D LK++
Sbjct: 1025 LAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQ 1084
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDM 288
+ K + L+ L E+ SE +++ KQ+ D
Sbjct: 1085 LAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRD- 1143
Query: 289 LNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLME-QLNDTENNSY 347
L+E+L + E +T+ + +L K + EL++ E+ T E Q+ D
Sbjct: 1144 LSEELEALKTELEDTL-DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHA 1202
Query: 348 KLIENMFNKVSQIASDFKIS---NQLSCELDDESENTYERISLTLDKITNH-ITYLNTQI 403
+E + ++ Q A FK + N+ E D++ ++ + + H L+ Q+
Sbjct: 1203 TALEELSEQLEQ-AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQV 1261
Query: 404 NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL- 462
E + E + +L E+ L+ L + T +E E + ++ + + +L
Sbjct: 1262 QELHAK-----VSEGDRLRVELAEKASKLQNELDNVSTLLEE--AEKKGIKFAKDAASLE 1314
Query: 463 -NLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
L+D+ S+ I ++ + + Q E+ ++ K +K++
Sbjct: 1315 SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1366
Score = 45.2 bits (102), Expect = 6e-04
Identities = 73/330 (22%), Positives = 131/330 (39%), Gaps = 34/330 (10%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + N ++ ++ L++ + +++EL S + LE E T E+
Sbjct: 1491 ALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE 1550
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + +K + + LQ + I + E+
Sbjct: 1551 LEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEK---------KRLLIKQVREL 1601
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+ L +E+ K EID+ + L N+ E L L ++ +R
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDL--KDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1659
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI---SNQLSCELDDESEN 380
ELEE + + Q ++E L + ++AS + + Q EL DE N
Sbjct: 1660 ELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719
Query: 381 TYERISLTLD---KITNHITYLNTQINETQKNDNAQLLWEA-KKQIADLTEQNIILKERL 436
+ S LD ++ I L ++ E Q N +LL + +K + N L
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSN--MELLNDRFRKTTLQVDTLNAELAAER 1777
Query: 437 S----------QLETENKELLIEIQTVRGS 456
S QLE +NKEL ++Q + G+
Sbjct: 1778 SAAQKSDNARQQLERQNKELKAKLQELEGA 1807
Score = 44.4 bits (100), Expect = 0.001
Identities = 89/474 (18%), Positives = 193/474 (40%), Gaps = 64/474 (13%)
Query: 88 ETKHNDLKKLYEDSAS---ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+ K +L K+ E ELE ++R++ Q+ + ++ E + + TE+ F
Sbjct: 855 QAKDEELLKVKEKQTKVEGELEEMERKHQQL-LEEKNILAEQLQAETEL-------FAEA 906
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINE---LRNSIKYLESVKSEYNTAN 201
EE+ + KK + + +++ +++ +N+ NE ++ I+ LE E A
Sbjct: 907 EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
+KL + A K ++EE+ LL+ +N ++ E
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAE--------E 1018
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
E K + L++I+ K E +++ +K R+E + ++ + +DL ++ +
Sbjct: 1019 EEKA----KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 322 ERELEEKQEQLTHLMEQL------NDTE----NNSYKLIENMFNKVSQIASDFKI----- 366
+ +++E + QL E+L D E NN+ K++ + +++++ DF+
Sbjct: 1075 QAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASR 1134
Query: 367 --SNQLSCELDDESENTYERISLTLD----------KITNHITYLNTQINETQKNDNAQL 414
+ + +L +E E + TLD K + L + E KN AQ+
Sbjct: 1135 NKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQI 1194
Query: 415 ----------LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNL 464
L E +Q+ L++ LET+NKEL E++ ++ E
Sbjct: 1195 QDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR 1254
Query: 465 KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE-LKLGK 517
K ++ K + +++ +++ ++++ +K+ +K K
Sbjct: 1255 KKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAK 1308
Score = 43.2 bits (97), Expect = 0.002
Identities = 75/368 (20%), Positives = 146/368 (39%), Gaps = 33/368 (8%)
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLL 225
K L++ + + T + EL + ++ E K + + Q + ++ EE L
Sbjct: 1534 KRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593
Query: 226 KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQE 285
I+ L+ ++ K +L++++ + K +DE KQ
Sbjct: 1594 LIKQVRELEAELEDERKQRALAVA--SKKKMEIDLKDLEAQIEAAN----KARDEVIKQ- 1646
Query: 286 IDMLNEKLICDRREFNETMQEKNILLS---DLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
+ L ++ +RE E ++ + + + KK+ E E+ + QE+L
Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHA 1706
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSC---ELDDESENTYERISLTLD---KITNHI 396
E +L + + N S ++ +L +L++E E + L D K T +
Sbjct: 1707 EQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQV 1766
Query: 397 TYLNTQI----NETQKNDNA--QLLWEAKKQIADLTEQNIILKER----LSQLETENKEL 446
LN ++ + QK+DNA QL + K+ A L E +K + +S LE + +L
Sbjct: 1767 DTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQL 1826
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVM 506
E Q + + E N T ++ED + ++K Q E + M
Sbjct: 1827 --EEQLEQEAKERAAANKLVRRTEKKLKEIFM-----QVEDERRHADQYKEQMEKANARM 1879
Query: 507 KQQQKELK 514
KQ +++L+
Sbjct: 1880 KQLKRQLE 1887
Score = 40.7 bits (91), Expect = 0.012
Identities = 66/384 (17%), Positives = 154/384 (40%), Gaps = 20/384 (5%)
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTS--DVMVVPEIIDSLTEVINTLTNGFES-L 144
ETK L + E++ E +R+N Q+ D+M + + + E +
Sbjct: 1482 ETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQV 1541
Query: 145 EEVALEIDLKKNSI--TKD-NISIKTLLDKLITKNETDIN--ELRNSIKYLESVKSEYNT 199
EE+ +++ ++ + T+D + ++ + + + E D+ + +N K +K
Sbjct: 1542 EEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVREL 1601
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E E+ A+ + + E+DL +E Q +D +
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD-YQRE 1660
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQ---EIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
LEE + +E ++ KE ++ K EI L E+L R QE++ L +++
Sbjct: 1661 LEEARASR-DEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719
Query: 317 KVNKTERELEEK---QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ L+EK + ++ L E+L + ++N +L+ + F K +
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSN-MELLNDRFRKTTLQVDTLNAELAAERS 1778
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQL---LWEAKKQIADLTEQNI 430
+S+N +++ ++ + L + K + L + + ++Q+ ++
Sbjct: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1838
Query: 431 ILKERLSQLETENKELLIEIQTVR 454
+ + + E + KE+ ++++ R
Sbjct: 1839 AANKLVRRTEKKLKEIFMQVEDER 1862
Score = 37.1 bits (82), Expect = 0.15
Identities = 49/259 (18%), Positives = 106/259 (40%), Gaps = 20/259 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
+E + +E+L ++KEK + E++ + R+ + ++EKNIL L + +
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEME-------RKHQQLLEEKNILAEQLQAE-TE 901
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE-SE 379
E EE + +L ++L + ++ +E + + ++ K +L+++ E
Sbjct: 902 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 961
Query: 380 NTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL 439
R L L+K+T + D + KK + D + E SQL
Sbjct: 962 EEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR------IAECSSQL 1015
Query: 440 ETENKELLIEIQTVRGSNE----EVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
E +E + +R E ++ LK E D++ ++ E
Sbjct: 1016 -AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 496 KSQFEDLDDVMKQQQKELK 514
++Q ++L + ++++EL+
Sbjct: 1075 QAQIDELKLQLAKKEEELQ 1093
Score = 35.9 bits (79), Expect = 0.34
Identities = 41/159 (25%), Positives = 73/159 (45%), Gaps = 15/159 (9%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQLSC--E 373
+V + E EL+ K E+L + E+ E +E M K Q+ + I + QL E
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGE----LEEMERKHQQLLEEKNILAEQLQAETE 901
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
L E+E R++ ++ + L +++ E ++ N L E KK A + + L+
Sbjct: 902 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEER-NQILQNEKKKMQAHIQD----LE 956
Query: 434 ERLSQLETENKELLIEIQTVRG---SNEEVTLNLKDSST 469
E+L + E ++L +E T EE L L+D ++
Sbjct: 957 EQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNS 995
>BC117691-1|AAI17692.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 54.8 bits (126), Expect = 7e-07
Identities = 78/440 (17%), Positives = 181/440 (41%), Gaps = 29/440 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K +E K ++++ +++L L EK + + + +++ L E++ +
Sbjct: 1247 KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKF 1306
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNISIK 166
++ + S + E++ T L++ LEE +L+ ++ + N+ +
Sbjct: 1307 AKDAASLE-SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ 1365
Query: 167 TL-LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNCI 218
L L + + +++ +I+ LE K + E L ++L A DK +N +
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 219 QEEVDLLKIENQNLLQXXXXX-----------XXXXXXXXXXXXARDKFIANLEEMKTML 267
Q+E+D L ++ + Q RD+ A E +T
Sbjct: 1426 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA 1485
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEE 327
+ L+ E+ K+E + N++L D + + + + +L K E+++EE
Sbjct: 1486 LS--LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEE 1543
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
+ QL L ++L TE+ +L NM +Q D + ++ + +++ +++
Sbjct: 1544 MRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE---QNEEKKRLLIKQVRE 1600
Query: 388 TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
++ + + +K + EA+ + A+ +I ++L +L+ + K+
Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVI--KQLRKLQAQMKDYQ 1658
Query: 448 IEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K+S
Sbjct: 1659 RELEEARASRDEIFAQSKES 1678
Score = 46.4 bits (105), Expect = 2e-04
Identities = 95/513 (18%), Positives = 193/513 (37%), Gaps = 34/513 (6%)
Query: 14 NIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXX 73
++++ I + +++E ++ + + LQ + GD KN+ + ++R+L
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLH-KNNALK-VVRELQAQIAEL 1123
Query: 74 XXXXXXLTEKLTIAETKHNDLKKLYEDSASELE------ALKRENIQMHTSDVMVVPEII 127
AE + DL + E +ELE A ++E +V + + +
Sbjct: 1124 QEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAL 1183
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+ T+ ALE +L + + K L+K ETD EL +
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALE-ELSEQ--LEQAKRFKANLEKNKQGLETDNKELACEV 1240
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
K L+ VK+E +KL Q V + + E D L++E
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQ----VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLL 1296
Query: 248 XXXXARD-KFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
+ KF + +++ L +E L E + N I L E ++ E
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEE----EKNSLQEQQ 1352
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+E+ +L K+V + +L + ++++ + + E KL+++ +SQ +
Sbjct: 1353 EEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDA-EALSQRLEEK 1411
Query: 365 KISNQLSCELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDNAQLLWEAKKQ 421
++ D+ E T R+ LD +T +H + + + + QK + QLL E K
Sbjct: 1412 ALAY-------DKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFD-QLLAEEKSI 1463
Query: 422 IADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXX 481
A E+ + + ET+ L ++ + EE K
Sbjct: 1464 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1523
Query: 482 SNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ +++ + Q E++ +++ + EL+
Sbjct: 1524 GKNVHELEKSKRALEQQVEEMRTQLEELEDELQ 1556
Score = 45.2 bits (102), Expect = 6e-04
Identities = 69/352 (19%), Positives = 142/352 (40%), Gaps = 17/352 (4%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
L K+ K E I++L +K E + E A KL + + D+ +Q ++D LK++
Sbjct: 1025 LAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQ 1084
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDM 288
+ K + L+ L E+ SE +++ KQ+ D
Sbjct: 1085 LAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRD- 1143
Query: 289 LNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLME-QLNDTENNSY 347
L+E+L + E +T+ + +L K + EL++ E+ T E Q+ D
Sbjct: 1144 LSEELEALKTELEDTL-DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHA 1202
Query: 348 KLIENMFNKVSQIASDFKIS---NQLSCELDDESENTYERISLTLDKITNH-ITYLNTQI 403
+E + ++ Q A FK + N+ E D++ ++ + + H L+ Q+
Sbjct: 1203 TALEELSEQLEQ-AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQV 1261
Query: 404 NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL- 462
E + E + +L E+ L+ L + T +E E + ++ + + +L
Sbjct: 1262 QELHAK-----VSEGDRLRVELAEKASKLQNELDNVSTLLEE--AEKKGIKFAKDAASLE 1314
Query: 463 -NLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
L+D+ S+ I ++ + + Q E+ ++ K +K++
Sbjct: 1315 SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1366
Score = 45.2 bits (102), Expect = 6e-04
Identities = 73/330 (22%), Positives = 131/330 (39%), Gaps = 34/330 (10%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + N ++ ++ L++ + +++EL S + LE E T E+
Sbjct: 1491 ALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE 1550
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + +K + + LQ + I + E+
Sbjct: 1551 LEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEK---------KRLLIKQVREL 1601
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+ L +E+ K EID+ + L N+ E L L ++ +R
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDL--KDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1659
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI---SNQLSCELDDESEN 380
ELEE + + Q ++E L + ++AS + + Q EL DE N
Sbjct: 1660 ELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719
Query: 381 TYERISLTLD---KITNHITYLNTQINETQKNDNAQLLWEA-KKQIADLTEQNIILKERL 436
+ S LD ++ I L ++ E Q N +LL + +K + N L
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSN--MELLNDRFRKTTLQVDTLNAELAAER 1777
Query: 437 S----------QLETENKELLIEIQTVRGS 456
S QLE +NKEL ++Q + G+
Sbjct: 1778 SAAQKSDNARQQLERQNKELKAKLQELEGA 1807
Score = 44.4 bits (100), Expect = 0.001
Identities = 89/474 (18%), Positives = 193/474 (40%), Gaps = 64/474 (13%)
Query: 88 ETKHNDLKKLYEDSAS---ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+ K +L K+ E ELE ++R++ Q+ + ++ E + + TE+ F
Sbjct: 855 QAKDEELLKVKEKQTKVEGELEEMERKHQQL-LEEKNILAEQLQAETEL-------FAEA 906
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINE---LRNSIKYLESVKSEYNTAN 201
EE+ + KK + + +++ +++ +N+ NE ++ I+ LE E A
Sbjct: 907 EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
+KL + A K ++EE+ LL+ +N ++ E
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAE--------E 1018
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
E K + L++I+ K E +++ +K R+E + ++ + +DL ++ +
Sbjct: 1019 EEKA----KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 322 ERELEEKQEQLTHLMEQL------NDTE----NNSYKLIENMFNKVSQIASDFKI----- 366
+ +++E + QL E+L D E NN+ K++ + +++++ DF+
Sbjct: 1075 QAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASR 1134
Query: 367 --SNQLSCELDDESENTYERISLTLD----------KITNHITYLNTQINETQKNDNAQL 414
+ + +L +E E + TLD K + L + E KN AQ+
Sbjct: 1135 NKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQI 1194
Query: 415 ----------LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNL 464
L E +Q+ L++ LET+NKEL E++ ++ E
Sbjct: 1195 QDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR 1254
Query: 465 KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE-LKLGK 517
K ++ K + +++ +++ ++++ +K+ +K K
Sbjct: 1255 KKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAK 1308
Score = 43.2 bits (97), Expect = 0.002
Identities = 75/368 (20%), Positives = 146/368 (39%), Gaps = 33/368 (8%)
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLL 225
K L++ + + T + EL + ++ E K + + Q + ++ EE L
Sbjct: 1534 KRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593
Query: 226 KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQE 285
I+ L+ ++ K +L++++ + K +DE KQ
Sbjct: 1594 LIKQVRELEAELEDERKQRALAVA--SKKKMEIDLKDLEAQIEAAN----KARDEVIKQ- 1646
Query: 286 IDMLNEKLICDRREFNETMQEKNILLS---DLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
+ L ++ +RE E ++ + + + KK+ E E+ + QE+L
Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHA 1706
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSC---ELDDESENTYERISLTLD---KITNHI 396
E +L + + N S ++ +L +L++E E + L D K T +
Sbjct: 1707 EQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQV 1766
Query: 397 TYLNTQI----NETQKNDNA--QLLWEAKKQIADLTEQNIILKER----LSQLETENKEL 446
LN ++ + QK+DNA QL + K+ A L E +K + +S LE + +L
Sbjct: 1767 DTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQL 1826
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVM 506
E Q + + E N T ++ED + ++K Q E + M
Sbjct: 1827 --EEQLEQEAKERAAANKLVRRTEKKLKEIFM-----QVEDERRHADQYKEQMEKANARM 1879
Query: 507 KQQQKELK 514
KQ +++L+
Sbjct: 1880 KQLKRQLE 1887
Score = 40.7 bits (91), Expect = 0.012
Identities = 66/384 (17%), Positives = 154/384 (40%), Gaps = 20/384 (5%)
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTS--DVMVVPEIIDSLTEVINTLTNGFES-L 144
ETK L + E++ E +R+N Q+ D+M + + + E +
Sbjct: 1482 ETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQV 1541
Query: 145 EEVALEIDLKKNSI--TKD-NISIKTLLDKLITKNETDIN--ELRNSIKYLESVKSEYNT 199
EE+ +++ ++ + T+D + ++ + + + E D+ + +N K +K
Sbjct: 1542 EEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVREL 1601
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E E+ A+ + + E+DL +E Q +D +
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD-YQRE 1660
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQ---EIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
LEE + +E ++ KE ++ K EI L E+L R QE++ L +++
Sbjct: 1661 LEEARASR-DEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719
Query: 317 KVNKTERELEEK---QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ L+EK + ++ L E+L + ++N +L+ + F K +
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSN-MELLNDRFRKTTLQVDTLNAELAAERS 1778
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQL---LWEAKKQIADLTEQNI 430
+S+N +++ ++ + L + K + L + + ++Q+ ++
Sbjct: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1838
Query: 431 ILKERLSQLETENKELLIEIQTVR 454
+ + + E + KE+ ++++ R
Sbjct: 1839 AANKLVRRTEKKLKEIFMQVEDER 1862
Score = 37.1 bits (82), Expect = 0.15
Identities = 49/259 (18%), Positives = 106/259 (40%), Gaps = 20/259 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
+E + +E+L ++KEK + E++ + R+ + ++EKNIL L + +
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEME-------RKHQQLLEEKNILAEQLQAE-TE 901
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE-SE 379
E EE + +L ++L + ++ +E + + ++ K +L+++ E
Sbjct: 902 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 961
Query: 380 NTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL 439
R L L+K+T + D + KK + D + E SQL
Sbjct: 962 EEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR------IAECSSQL 1015
Query: 440 ETENKELLIEIQTVRGSNE----EVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
E +E + +R E ++ LK E D++ ++ E
Sbjct: 1016 -AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 496 KSQFEDLDDVMKQQQKELK 514
++Q ++L + ++++EL+
Sbjct: 1075 QAQIDELKLQLAKKEEELQ 1093
Score = 35.9 bits (79), Expect = 0.34
Identities = 41/159 (25%), Positives = 73/159 (45%), Gaps = 15/159 (9%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQLSC--E 373
+V + E EL+ K E+L + E+ E +E M K Q+ + I + QL E
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGE----LEEMERKHQQLLEEKNILAEQLQAETE 901
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
L E+E R++ ++ + L +++ E ++ N L E KK A + + L+
Sbjct: 902 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEER-NQILQNEKKKMQAHIQD----LE 956
Query: 434 ERLSQLETENKELLIEIQTVRG---SNEEVTLNLKDSST 469
E+L + E ++L +E T EE L L+D ++
Sbjct: 957 EQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNS 995
>AF092564-1|AAC72361.1| 1202|Homo sapiens chromosome-associated
protein-C protein.
Length = 1202
Score = 54.8 bits (126), Expect = 7e-07
Identities = 65/296 (21%), Positives = 121/296 (40%), Gaps = 28/296 (9%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
+ E T E H D K++ E S +K +N DV + ++ +T+ I
Sbjct: 248 IAEMETQKEKIHEDTKEINEKSNILSNEMKAKN-----KDVKDTEKKLNKITKFIE---E 299
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNT 199
E V LE D++ K S L+K + K++ + E ++ ++ +E T
Sbjct: 300 NKEKFTHVDLE-DVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTT 358
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
N L ++ K ++E +D LK E Q L + N
Sbjct: 359 RNNALEKEKEKEEKK---LKEVMDSLKQETQGLQKEKESREKELMGFSKS--------VN 407
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
K + + +L + ++ E LI +ET++E+ + D+ K+
Sbjct: 408 EARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAA----SETLKERKAAIRDIEGKLP 463
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+TE+EL+EK+++L ++L E N L+ ++F KV + S +++ LD
Sbjct: 464 QTEQELKEKEKEL----QKLTQEETNFKSLVHDLFQKVEEAKSSLAMNSSRGKVLD 515
Score = 37.5 bits (83), Expect = 0.11
Identities = 26/113 (23%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
Query: 123 VPEIIDSLTEVIN-TLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDIN 181
V + +++ E+ N L + L+++ ++D ++ITK ++IKT D+ + K + +
Sbjct: 798 VKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKT-ADRNLQKAQDSVL 856
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
IK E + + L ++ V N +E + ++ E++NLLQ
Sbjct: 857 RTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQ 909
Score = 32.3 bits (70), Expect = 4.2
Identities = 36/185 (19%), Positives = 83/185 (44%), Gaps = 9/185 (4%)
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
++E++ + +L D ++ + +QE+ + L + K+ +ERE+ E+ T +++L +
Sbjct: 687 EEEVNKMESQLQNDSKKAMQ-IQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQ 745
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYL-NT 401
E ++ + V A D K +L E + Y+ ++ K+ + L NT
Sbjct: 746 EEYLNVQVKELEANVLATAPD-KKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNT 804
Query: 402 --QINETQKNDNAQLLWEAKKQIAD----LTEQNIILKERLSQLETENKELLIEIQTVRG 455
+IN + L + KQ+ + +T+ + +K L+ +L + ++
Sbjct: 805 IVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKD 864
Query: 456 SNEEV 460
+ +EV
Sbjct: 865 TEKEV 869
Score = 31.9 bits (69), Expect = 5.6
Identities = 40/206 (19%), Positives = 86/206 (41%), Gaps = 27/206 (13%)
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYER 384
+E +E++ + QL +N+S K ++ KV K+ + + E NT E+
Sbjct: 683 IEISEEEVNKMESQL---QNDSKKAMQIQEQKVQLEERVVKLRHS-----EREMRNTLEK 734
Query: 385 ISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI--------ILKERL 436
+ ++ ++ YLN Q+ E + N A + KKQ L E+N+ + E+
Sbjct: 735 FTASIQRLIEQEEYLNVQVKELEANVLATAP-DKKKQ--KLLEENVSAFKTEYDAVAEKA 791
Query: 437 SQLETENKEL---LIEI-----QTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDM 488
++E E K L ++EI + + +++ L + ++ ++
Sbjct: 792 GKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKA 851
Query: 489 KTKVMEWKSQFEDLDDVMKQQQKELK 514
+ V+ + + +D + + ELK
Sbjct: 852 QDSVLRTEKEIKDTEKEVDDLTAELK 877
>AB210026-1|BAE06108.1| 2018|Homo sapiens MYH10 variant protein
protein.
Length = 2018
Score = 54.8 bits (126), Expect = 7e-07
Identities = 78/440 (17%), Positives = 181/440 (41%), Gaps = 29/440 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K +E K ++++ +++L L EK + + + +++ L E++ +
Sbjct: 1289 KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKF 1348
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNISIK 166
++ + S + E++ T L++ LEE +L+ ++ + N+ +
Sbjct: 1349 AKDAASLE-SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ 1407
Query: 167 TL-LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNCI 218
L L + + +++ +I+ LE K + E L ++L A DK +N +
Sbjct: 1408 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1467
Query: 219 QEEVDLLKIENQNLLQXXXXX-----------XXXXXXXXXXXXARDKFIANLEEMKTML 267
Q+E+D L ++ + Q RD+ A E +T
Sbjct: 1468 QQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA 1527
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEE 327
+ L+ E+ K+E + N++L D + + + + +L K E+++EE
Sbjct: 1528 LS--LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEE 1585
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
+ QL L ++L TE+ +L NM +Q D + ++ + +++ +++
Sbjct: 1586 MRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE---QNEEKKRLLIKQVRE 1642
Query: 388 TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
++ + + +K + EA+ + A+ +I ++L +L+ + K+
Sbjct: 1643 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVI--KQLRKLQAQMKDYQ 1700
Query: 448 IEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K+S
Sbjct: 1701 RELEEARASRDEIFAQSKES 1720
Score = 46.4 bits (105), Expect = 2e-04
Identities = 95/513 (18%), Positives = 193/513 (37%), Gaps = 34/513 (6%)
Query: 14 NIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXX 73
++++ I + +++E ++ + + LQ + GD KN+ + ++R+L
Sbjct: 1108 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLH-KNNALK-VVRELQAQIAEL 1165
Query: 74 XXXXXXLTEKLTIAETKHNDLKKLYEDSASELE------ALKRENIQMHTSDVMVVPEII 127
AE + DL + E +ELE A ++E +V + + +
Sbjct: 1166 QEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAL 1225
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+ T+ ALE +L + + K L+K ETD EL +
Sbjct: 1226 EEETKNHEAQIQDMRQRHATALE-ELSEQ--LEQAKRFKANLEKNKQGLETDNKELACEV 1282
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
K L+ VK+E +KL Q V + + E D L++E
Sbjct: 1283 KVLQQVKAESEHKRKKLDAQ----VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLL 1338
Query: 248 XXXXARD-KFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
+ KF + +++ L +E L E + N I L E ++ E
Sbjct: 1339 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEE----EKNSLQEQQ 1394
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+E+ +L K+V + +L + ++++ + + E KL+++ +SQ +
Sbjct: 1395 EEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDA-EALSQRLEEK 1453
Query: 365 KISNQLSCELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDNAQLLWEAKKQ 421
++ D+ E T R+ LD +T +H + + + + QK + QLL E K
Sbjct: 1454 ALAY-------DKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFD-QLLAEEKSI 1505
Query: 422 IADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXX 481
A E+ + + ET+ L ++ + EE K
Sbjct: 1506 SARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDV 1565
Query: 482 SNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ +++ + Q E++ +++ + EL+
Sbjct: 1566 GKNVHELEKSKRALEQQVEEMRTQLEELEDELQ 1598
Score = 45.2 bits (102), Expect = 6e-04
Identities = 69/352 (19%), Positives = 142/352 (40%), Gaps = 17/352 (4%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
L K+ K E I++L +K E + E A KL + + D+ +Q ++D LK++
Sbjct: 1067 LAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQ 1126
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDM 288
+ K + L+ L E+ SE +++ KQ+ D
Sbjct: 1127 LAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRD- 1185
Query: 289 LNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLME-QLNDTENNSY 347
L+E+L + E +T+ + +L K + EL++ E+ T E Q+ D
Sbjct: 1186 LSEELEALKTELEDTL-DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHA 1244
Query: 348 KLIENMFNKVSQIASDFKIS---NQLSCELDDESENTYERISLTLDKITNH-ITYLNTQI 403
+E + ++ Q A FK + N+ E D++ ++ + + H L+ Q+
Sbjct: 1245 TALEELSEQLEQ-AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQV 1303
Query: 404 NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL- 462
E + E + +L E+ L+ L + T +E E + ++ + + +L
Sbjct: 1304 QELHAK-----VSEGDRLRVELAEKASKLQNELDNVSTLLEE--AEKKGIKFAKDAASLE 1356
Query: 463 -NLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
L+D+ S+ I ++ + + Q E+ ++ K +K++
Sbjct: 1357 SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1408
Score = 45.2 bits (102), Expect = 6e-04
Identities = 73/330 (22%), Positives = 131/330 (39%), Gaps = 34/330 (10%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + N ++ ++ L++ + +++EL S + LE E T E+
Sbjct: 1533 ALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE 1592
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + +K + + LQ + I + E+
Sbjct: 1593 LEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEK---------KRLLIKQVREL 1643
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+ L +E+ K EID+ + L N+ E L L ++ +R
Sbjct: 1644 EAELEDERKQRALAVASKKKMEIDL--KDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1701
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI---SNQLSCELDDESEN 380
ELEE + + Q ++E L + ++AS + + Q EL DE N
Sbjct: 1702 ELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1761
Query: 381 TYERISLTLD---KITNHITYLNTQINETQKNDNAQLLWEA-KKQIADLTEQNIILKERL 436
+ S LD ++ I L ++ E Q N +LL + +K + N L
Sbjct: 1762 SASGKSALLDEKRRLEARIAQLEEELEEEQSN--MELLNDRFRKTTLQVDTLNAELAAER 1819
Query: 437 S----------QLETENKELLIEIQTVRGS 456
S QLE +NKEL ++Q + G+
Sbjct: 1820 SAAQKSDNARQQLERQNKELKAKLQELEGA 1849
Score = 44.4 bits (100), Expect = 0.001
Identities = 89/474 (18%), Positives = 193/474 (40%), Gaps = 64/474 (13%)
Query: 88 ETKHNDLKKLYEDSAS---ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+ K +L K+ E ELE ++R++ Q+ + ++ E + + TE+ F
Sbjct: 897 QAKDEELLKVKEKQTKVEGELEEMERKHQQL-LEEKNILAEQLQAETEL-------FAEA 948
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINE---LRNSIKYLESVKSEYNTAN 201
EE+ + KK + + +++ +++ +N+ NE ++ I+ LE E A
Sbjct: 949 EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 1008
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
+KL + A K ++EE+ LL+ +N ++ E
Sbjct: 1009 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAE--------E 1060
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
E K + L++I+ K E +++ +K R+E + ++ + +DL ++ +
Sbjct: 1061 EEKA----KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1116
Query: 322 ERELEEKQEQLTHLMEQL------NDTE----NNSYKLIENMFNKVSQIASDFKI----- 366
+ +++E + QL E+L D E NN+ K++ + +++++ DF+
Sbjct: 1117 QAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASR 1176
Query: 367 --SNQLSCELDDESENTYERISLTLD----------KITNHITYLNTQINETQKNDNAQL 414
+ + +L +E E + TLD K + L + E KN AQ+
Sbjct: 1177 NKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQI 1236
Query: 415 ----------LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNL 464
L E +Q+ L++ LET+NKEL E++ ++ E
Sbjct: 1237 QDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR 1296
Query: 465 KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE-LKLGK 517
K ++ K + +++ +++ ++++ +K+ +K K
Sbjct: 1297 KKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAK 1350
Score = 43.2 bits (97), Expect = 0.002
Identities = 75/368 (20%), Positives = 146/368 (39%), Gaps = 33/368 (8%)
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLL 225
K L++ + + T + EL + ++ E K + + Q + ++ EE L
Sbjct: 1576 KRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1635
Query: 226 KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQE 285
I+ L+ ++ K +L++++ + K +DE KQ
Sbjct: 1636 LIKQVRELEAELEDERKQRALAVA--SKKKMEIDLKDLEAQIEAAN----KARDEVIKQ- 1688
Query: 286 IDMLNEKLICDRREFNETMQEKNILLS---DLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
+ L ++ +RE E ++ + + + KK+ E E+ + QE+L
Sbjct: 1689 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHA 1748
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSC---ELDDESENTYERISLTLD---KITNHI 396
E +L + + N S ++ +L +L++E E + L D K T +
Sbjct: 1749 EQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQV 1808
Query: 397 TYLNTQI----NETQKNDNA--QLLWEAKKQIADLTEQNIILKER----LSQLETENKEL 446
LN ++ + QK+DNA QL + K+ A L E +K + +S LE + +L
Sbjct: 1809 DTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQL 1868
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVM 506
E Q + + E N T ++ED + ++K Q E + M
Sbjct: 1869 --EEQLEQEAKERAAANKLVRRTEKKLKEIFM-----QVEDERRHADQYKEQMEKANARM 1921
Query: 507 KQQQKELK 514
KQ +++L+
Sbjct: 1922 KQLKRQLE 1929
Score = 40.7 bits (91), Expect = 0.012
Identities = 66/384 (17%), Positives = 154/384 (40%), Gaps = 20/384 (5%)
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTS--DVMVVPEIIDSLTEVINTLTNGFES-L 144
ETK L + E++ E +R+N Q+ D+M + + + E +
Sbjct: 1524 ETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQV 1583
Query: 145 EEVALEIDLKKNSI--TKD-NISIKTLLDKLITKNETDIN--ELRNSIKYLESVKSEYNT 199
EE+ +++ ++ + T+D + ++ + + + E D+ + +N K +K
Sbjct: 1584 EEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVREL 1643
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E E+ A+ + + E+DL +E Q +D +
Sbjct: 1644 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD-YQRE 1702
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQ---EIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
LEE + +E ++ KE ++ K EI L E+L R QE++ L +++
Sbjct: 1703 LEEARASR-DEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1761
Query: 317 KVNKTERELEEK---QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ L+EK + ++ L E+L + ++N +L+ + F K +
Sbjct: 1762 SASGKSALLDEKRRLEARIAQLEEELEEEQSN-MELLNDRFRKTTLQVDTLNAELAAERS 1820
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQL---LWEAKKQIADLTEQNI 430
+S+N +++ ++ + L + K + L + + ++Q+ ++
Sbjct: 1821 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1880
Query: 431 ILKERLSQLETENKELLIEIQTVR 454
+ + + E + KE+ ++++ R
Sbjct: 1881 AANKLVRRTEKKLKEIFMQVEDER 1904
Score = 37.1 bits (82), Expect = 0.15
Identities = 49/259 (18%), Positives = 106/259 (40%), Gaps = 20/259 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
+E + +E+L ++KEK + E++ + R+ + ++EKNIL L + +
Sbjct: 892 QEEELQAKDEELLKVKEKQTKVEGELEEME-------RKHQQLLEEKNILAEQLQAE-TE 943
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE-SE 379
E EE + +L ++L + ++ +E + + ++ K +L+++ E
Sbjct: 944 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 1003
Query: 380 NTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL 439
R L L+K+T + D + KK + D + E SQL
Sbjct: 1004 EEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR------IAECSSQL 1057
Query: 440 ETENKELLIEIQTVRGSNE----EVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
E +E + +R E ++ LK E D++ ++ E
Sbjct: 1058 -AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1116
Query: 496 KSQFEDLDDVMKQQQKELK 514
++Q ++L + ++++EL+
Sbjct: 1117 QAQIDELKLQLAKKEEELQ 1135
Score = 35.9 bits (79), Expect = 0.34
Identities = 41/159 (25%), Positives = 73/159 (45%), Gaps = 15/159 (9%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQLSC--E 373
+V + E EL+ K E+L + E+ E +E M K Q+ + I + QL E
Sbjct: 888 QVTRQEEELQAKDEELLKVKEKQTKVEGE----LEEMERKHQQLLEEKNILAEQLQAETE 943
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
L E+E R++ ++ + L +++ E ++ N L E KK A + + L+
Sbjct: 944 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEER-NQILQNEKKKMQAHIQD----LE 998
Query: 434 ERLSQLETENKELLIEIQTVRG---SNEEVTLNLKDSST 469
E+L + E ++L +E T EE L L+D ++
Sbjct: 999 EQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNS 1037
>AB019987-1|BAA73535.1| 1288|Homo sapiens chromosome-associated
polypeptide-C protein.
Length = 1288
Score = 54.8 bits (126), Expect = 7e-07
Identities = 65/296 (21%), Positives = 121/296 (40%), Gaps = 28/296 (9%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
+ E T E H D K++ E S +K +N DV + ++ +T+ I
Sbjct: 334 IAEMETQKEKIHEDTKEINEKSNILSNEMKAKN-----KDVKDTEKKLNKITKFIEENKE 388
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNT 199
F L+ LE D++ K S L+K + K++ + E ++ ++ +E T
Sbjct: 389 KFTQLD---LE-DVQVREKLKHATSKAKKLEKQLQKDKEKVEEFKSIPAKSNNIINETTT 444
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
N L ++ K ++E +D LK E Q L + N
Sbjct: 445 RNNALEKEKEKEEKK---LKEVMDSLKQETQGLQKEKESREKELMGFSKS--------VN 493
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
K + + +L + ++ E LI +ET++E+ + D+ K+
Sbjct: 494 EARSKMDVAQSELDIYLSRHNTAVSQLTKAKEALIAA----SETLKERKAAIRDIEGKLP 549
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+TE+EL+EK+++L ++L E N L+ ++F KV + S ++ LD
Sbjct: 550 QTEQELKEKEKEL----QKLTQEETNFKSLVHDLFQKVEEAKSSLAMNRSRGKVLD 601
Score = 37.5 bits (83), Expect = 0.11
Identities = 26/113 (23%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
Query: 123 VPEIIDSLTEVIN-TLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDIN 181
V + +++ E+ N L + L+++ ++D ++ITK ++IKT D+ + K + +
Sbjct: 884 VKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKT-ADRNLQKAQDSVL 942
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
IK E + + L ++ V N +E + ++ E++NLLQ
Sbjct: 943 RTEKEIKDTEKEVDDLTAELKSLEDKAAEVVKNTNAAEESLPEIQKEHRNLLQ 995
Score = 32.3 bits (70), Expect = 4.2
Identities = 36/185 (19%), Positives = 83/185 (44%), Gaps = 9/185 (4%)
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
++E++ + +L D ++ + +QE+ + L + K+ +ERE+ E+ T +++L +
Sbjct: 773 EEEVNKMESQLQNDSKKAMQ-IQEQKVQLEERVVKLRHSEREMRNTLEKFTASIQRLIEQ 831
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYL-NT 401
E ++ + V A D K +L E + Y+ ++ K+ + L NT
Sbjct: 832 EEYLNVQVKELEANVLATAPD-KKKQKLLEENVSAFKTEYDAVAEKAGKVEAEVKRLHNT 890
Query: 402 --QINETQKNDNAQLLWEAKKQIAD----LTEQNIILKERLSQLETENKELLIEIQTVRG 455
+IN + L + KQ+ + +T+ + +K L+ +L + ++
Sbjct: 891 IVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKAQDSVLRTEKEIKD 950
Query: 456 SNEEV 460
+ +EV
Sbjct: 951 TEKEV 955
Score = 31.9 bits (69), Expect = 5.6
Identities = 40/206 (19%), Positives = 86/206 (41%), Gaps = 27/206 (13%)
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYER 384
+E +E++ + QL +N+S K ++ KV K+ + + E NT E+
Sbjct: 769 IEISEEEVNKMESQL---QNDSKKAMQIQEQKVQLEERVVKLRHS-----EREMRNTLEK 820
Query: 385 ISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI--------ILKERL 436
+ ++ ++ YLN Q+ E + N A + KKQ L E+N+ + E+
Sbjct: 821 FTASIQRLIEQEEYLNVQVKELEANVLATAP-DKKKQ--KLLEENVSAFKTEYDAVAEKA 877
Query: 437 SQLETENKEL---LIEI-----QTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDM 488
++E E K L ++EI + + +++ L + ++ ++
Sbjct: 878 GKVEAEVKRLHNTIVEINNHKLKAQQDKLDKINKQLDECASAITKAQVAIKTADRNLQKA 937
Query: 489 KTKVMEWKSQFEDLDDVMKQQQKELK 514
+ V+ + + +D + + ELK
Sbjct: 938 QDSVLRTEKEIKDTEKEVDDLTAELK 963
>X66397-1|CAA47021.1| 2349|Homo sapiens Tpr protein.
Length = 2349
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/448 (17%), Positives = 183/448 (40%), Gaps = 30/448 (6%)
Query: 80 LTEKLTIAETKHNDLK-KLYEDSASELEA------LKRENIQMHTSDVMVVPEIIDSLTE 132
L EKL + T +L+ KL E AS++ L++E +H+ + + E+ E
Sbjct: 148 LNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDE 207
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES 192
++ + E+ ++ KK +++ ++ ++ L T NE + + + L+
Sbjct: 208 LLALGREKGNEILELKCNLENKKEEVSR----LEEQMNGLKTSNEHLQKHVEDLLTKLKE 263
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
K + + EK +LN + N + D + ++ L + A
Sbjct: 264 AKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKA 323
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
+ +E+ K + +E L EK ++E++ N+ L +R+ +E+ +S
Sbjct: 324 IQDHLLEVEQSKDQMEKEML----EKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK-VSQIASDFKISNQLS 371
+ V K + + +LT L +T++ L+E + NK +++ + +
Sbjct: 380 PTAAAVAK----IVKPGMKLTELYNAYVETQDQ--LLLEKLENKRINKYLDEIVKEVEAK 433
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
+ YER + ++ + +I Q++ + +A KQ + L N
Sbjct: 434 APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTD-----KANKQSSVLERDNRR 488
Query: 432 LKERLSQLETENKELLIEIQTVRGSN--EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
++ ++ L + + LL+E++ RG++ + ++ D S+ N IE+++
Sbjct: 489 MEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRN-IEELQ 547
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+ +L + +++++E K
Sbjct: 548 QQNQRLLVALRELGETREREEQETTSSK 575
Score = 46.8 bits (106), Expect = 2e-04
Identities = 101/528 (19%), Positives = 219/528 (41%), Gaps = 55/528 (10%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
FK+ E+ Y EI + S Q+ + V + + E+ + QL
Sbjct: 46 FKVESEQQYFEIEKRLSHSQERL-VNETRECQSLRLELEKLNNQLKALTEK--------N 96
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L IA+ ++ ++ + + ELEA KR+ I+ + + + ++ LTE + L
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER----LSQELEYLTEDVKRLNEKL 152
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE------TDIN-ELRNSIKYLESVK 194
+ E+ LK + + ++S+K +L + E T +N EL+ L ++
Sbjct: 153 KESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALG 212
Query: 195 SEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA-R 253
E +L L N ++ + ++E+++ LK N++L + +
Sbjct: 213 REKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASME 272
Query: 254 DKFIANLE-EMK-TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+KF L +K + L + + + K + ++ L+ KL+ + E N+ +Q+ L
Sbjct: 273 EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELH-KLLKEAGEANKAIQDH---L 328
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLND----TENNSYKLIENMFNKVSQIAS----- 362
++ + ++ E+E+ EK +L +E ND T+ L E +S A+
Sbjct: 329 LEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKI 388
Query: 363 ---DFKISNQLSCELDDESENTYE-----RISLTLDKITNHI----TYLNTQINETQKND 410
K++ + ++ + + E RI+ LD+I + L Q E ++
Sbjct: 389 VKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQ 448
Query: 411 NAQL-----LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
A L +A K+I L E ++ S LE +N+ + I+++ + + + L+
Sbjct: 449 KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELE 508
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
++ S +I + + + +++++ +Q Q+ L
Sbjct: 509 EA--RGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLL 554
Score = 46.4 bits (105), Expect = 2e-04
Identities = 82/424 (19%), Positives = 171/424 (40%), Gaps = 29/424 (6%)
Query: 32 EIGQLKS-GLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXL--TEKLTIAE 88
E+ Q++S +Q V + ++ + EL+ D +N+ ++ + TE + +
Sbjct: 1215 EVAQVESLRYRQRVELLERELQELE-DSLNAEREKVQVTAKTMAQHEELMKKTETMNVVM 1273
Query: 89 TKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVA 148
+ L++ E +L+ ++ + ++ D++ + E L+E L + LEE
Sbjct: 1274 ETNKMLREEKERLEQDLQQMQAK-VRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDV 1332
Query: 149 LEIDLKKNSITKDNISIKTL-LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
+ + T KL+++ E ++ + + +K+E +N L
Sbjct: 1333 KRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASL--- 1389
Query: 208 LNNAVDKQNCIQE-EVDLLKIENQN-LLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKT 265
NN QN IQ + DL K+ + +Q + K I KT
Sbjct: 1390 TNN----QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGR--RYKT 1443
Query: 266 MLVEEKLSEIKEKDENFKQEIDMLNEKL-ICDRREFNETMQEKNILLSDLSKKVNKTERE 324
E K + K + + + D + + + + +E ET+ + L +V ++
Sbjct: 1444 QYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKT 1503
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYER 384
L EK+ + +L EQ ++ +L +++ ++ +Q QL ++ ++ E T +
Sbjct: 1504 LSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQ-------EEQLRQQITEKEEKTRKA 1556
Query: 385 ISLTLDKITNHITYLNTQI---NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
I KI H+ + Q+ NE K N L + + +T + R+S+LE
Sbjct: 1557 IVAAKSKIA-HLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLER 1615
Query: 442 ENKE 445
E +E
Sbjct: 1616 ELRE 1619
Score = 45.6 bits (103), Expect = 4e-04
Identities = 61/331 (18%), Positives = 130/331 (39%), Gaps = 14/331 (4%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E ++ EL +S+ E K + E+L + N + E +L+ E + L Q
Sbjct: 1232 ERELQELEDSLN-AEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDL 1290
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTML-VEEKLSEIKEKDENFKQEIDMLNEKLIC 295
+ A L E ML E+KL E K + + +++++
Sbjct: 1291 QQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQ-HLVSQQKDP 1349
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
D E+ + + EK + +K++ + E+ + ++ L + +N L E++ N
Sbjct: 1350 DTEEYRKLLSEKEVH----TKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDL-N 1404
Query: 356 KVSQIASDFKISNQLSCELDD--ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQ 413
KV I L ++ D E T ++ + L Q ++ + +AQ
Sbjct: 1405 KVR--TEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMET-SAQ 1461
Query: 414 LLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
+ ++Q + E LKE L+Q ET++K L +++ ++ + E ++
Sbjct: 1462 SSGDHQEQHVSVQEMQE-LKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQ 1520
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDD 504
+++D T+ + + Q + ++
Sbjct: 1521 LQSELSRLRQDLQDRTTQEEQLRQQITEKEE 1551
Score = 36.7 bits (81), Expect = 0.20
Identities = 55/305 (18%), Positives = 125/305 (40%), Gaps = 32/305 (10%)
Query: 53 ELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKREN 112
E+ I + ++ LT + ++ DL K+ +E E ++++
Sbjct: 1362 EVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKV----RTEKETIQKD- 1416
Query: 113 IQMHTSDVMVVPEIIDSLTEVINTLTNGFESL---EEVALEIDLKKNSITKD-NISIKTL 168
+ D+ + I + ++ +E L ++ +E + + ++ ++S++ +
Sbjct: 1417 LDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEM 1476
Query: 169 --LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLK 226
L + + + ET L + ++ L+ SE T L EQ + + +++++
Sbjct: 1477 QELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRT 1536
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEI 286
+ + L Q ++ IA+L +K L +E E+K+++ Q+
Sbjct: 1537 TQEEQLRQQITEKEEKTRKAIVAAKSK---IAHLAGVKDQLTKEN-EELKQRNGALDQQK 1592
Query: 287 DMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNS 346
D L+ ++ L S ++++ EREL E QE+ HL EQ ++ + S
Sbjct: 1593 DELDVRITA--------------LKSQYEGRISRLERELREHQER--HL-EQRDEPQEPS 1635
Query: 347 YKLIE 351
K+ E
Sbjct: 1636 NKVPE 1640
Score = 35.5 bits (78), Expect = 0.46
Identities = 65/359 (18%), Positives = 154/359 (42%), Gaps = 34/359 (9%)
Query: 125 EIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNIS-IKTLLDKLITKNETDINEL 183
E ++ L E + L + + L+ K+ + +DN+ + + L +N+
Sbjct: 695 EQLEKLQEQVTDLRSQNTKIS-TQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATT 753
Query: 184 RNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXX 243
+ + + ++ + ANEKL V +N +++E ++LK+ L Q
Sbjct: 754 QKQEQIINTMTQDLRGANEKLAVA---EVRAEN-LKKEKEMLKLSEVRLSQQRESLLAEQ 809
Query: 244 XXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
++ + NL+ ++ +L E +E K++ +I+ L ++ +++
Sbjct: 810 R-------GQNLLLTNLQTIQGIL-ERSETETKQR---LSSQIEKLEHEISHLKKKLENE 858
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+++++ L +L ++ T+R+L+ + + E L + + L +++ N Q+AS
Sbjct: 859 VEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQ 918
Query: 364 F-------KISNQLSC-ELDDESENTYERISLTLDKI---TNHITYLNTQIN--ETQKND 410
+ SN+ +L + T E+++ +++ T+++ + E N
Sbjct: 919 SSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNK 978
Query: 411 NAQLLWEAKKQI----ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
Q+ E +K I + E L+++L ++E E +EL + + S E+ LK
Sbjct: 979 EKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELK 1037
Score = 34.7 bits (76), Expect = 0.80
Identities = 83/438 (18%), Positives = 177/438 (40%), Gaps = 37/438 (8%)
Query: 92 NDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEI 151
+DL + ++ LK E ++ TS+V ++ SL E +N + EEV I
Sbjct: 935 DDLVSQLRQTEEQVNDLK-ERLKTSTSNVEQYQAMVTSLEESLNKEK---QVTEEVRKNI 990
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKY-LESVKSEYNTANEKLFEQLNN 210
+++ K++ +T L+K + + E + EL++ + +ES++ + + +K + N
Sbjct: 991 EVR----LKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSEL-KKTLSSVQN 1045
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE 270
V Q +Q L E Q A++E ++ +E
Sbjct: 1046 EV--QEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQA--AKE 1101
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD-LSKKVNKTERELEEKQ 329
++S++ + +Q ++ +K E + +E+ +L D +SK V + E +LE++
Sbjct: 1102 QVSKMA----SVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCE-DLEKQN 1156
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL-------DDESENTY 382
L +E+L+D S K E + ++ S+ S + E+ + +E +
Sbjct: 1157 RLLHDQIEKLSDKVVASVK--EGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRF 1214
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNA-----QLLWEAKKQIADL---TEQNIILKE 434
E + + + L ++ E + + NA Q+ + Q +L TE ++ E
Sbjct: 1215 EVAQVESLRYRQRVELLERELQELEDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVME 1274
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
L E + L ++Q ++ ++ L++ E + ++ V
Sbjct: 1275 TNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKR 1334
Query: 495 WKSQFEDLDDVMKQQQKE 512
WK++ + L K E
Sbjct: 1335 WKARNQHLVSQQKDPDTE 1352
Score = 31.9 bits (69), Expect = 5.6
Identities = 64/363 (17%), Positives = 148/363 (40%), Gaps = 24/363 (6%)
Query: 40 LQQNVGVGDKTVAEL--KNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKL 97
LQ NV + + L +N ++ + ++ EKL +AE + +LKK
Sbjct: 728 LQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKE 787
Query: 98 YED-SASELE-ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKK 155
E SE+ + +RE++ ++ + ++ ++ E+ + ++ +I+ +
Sbjct: 788 KEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSET--ETKQRLSSQIEKLE 845
Query: 156 NSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE-QLNNAVDK 214
+ I+ ++ +++ T +L ++ + L++ + + E L Q A K
Sbjct: 846 HEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLK 905
Query: 215 QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE-MKTML--VEEK 271
Q+ EV + +Q + ++ + +L+E +KT VE+
Sbjct: 906 QHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQY 965
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
+ + +E+ +E + E R+ ++E + L KK+ + E+E +E Q+
Sbjct: 966 QAMVTSLEESLNKEKQVTEEV----RKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDD 1021
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQI--ASDFKISNQLSCELD--------DESENT 381
+E + + K + ++ N+V + + +SN+ D E++N
Sbjct: 1022 KRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNK 1081
Query: 382 YER 384
YER
Sbjct: 1082 YER 1084
>X63105-1|CAA44819.1| 726|Homo sapiens Tpr protein.
Length = 726
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/448 (17%), Positives = 183/448 (40%), Gaps = 30/448 (6%)
Query: 80 LTEKLTIAETKHNDLK-KLYEDSASELEA------LKRENIQMHTSDVMVVPEIIDSLTE 132
L EKL + T +L+ KL E AS++ L++E +H+ + + E+ E
Sbjct: 148 LNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDE 207
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES 192
++ + E+ ++ KK +++ ++ ++ L T NE + + + L+
Sbjct: 208 LLALGREKGNEILELKCNLENKKEEVSR----LEEQMNGLKTSNEHLQKHVEDLLTKLKE 263
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
K + + EK +LN + N + D + ++ L + A
Sbjct: 264 AKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKA 323
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
+ +E+ K + +E L EK ++E++ N+ L +R+ +E+ +S
Sbjct: 324 IQDHLLEVEQSKDQMEKEML----EKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK-VSQIASDFKISNQLS 371
+ V K + + +LT L +T++ L+E + NK +++ + +
Sbjct: 380 PTAAAVAK----IVKPGMKLTELYNAYVETQDQ--LLLEKLENKRINKYLDEIVKEVEAK 433
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
+ YER + ++ + +I Q++ + +A KQ + L N
Sbjct: 434 APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTD-----KANKQSSVLERDNRR 488
Query: 432 LKERLSQLETENKELLIEIQTVRGSN--EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
++ ++ L + + LL+E++ RG++ + ++ D S+ N IE+++
Sbjct: 489 MEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRN-IEELQ 547
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+ +L + +++++E K
Sbjct: 548 QQNQRLLVALRELGETREREEQETTSSK 575
Score = 46.8 bits (106), Expect = 2e-04
Identities = 101/528 (19%), Positives = 219/528 (41%), Gaps = 55/528 (10%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
FK+ E+ Y EI + S Q+ + V + + E+ + QL
Sbjct: 46 FKVESEQQYFEIEKRLSHSQERL-VNETRECQSLRLELEKLNNQLKALTEK--------N 96
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L IA+ ++ ++ + + ELEA KR+ I+ + + + ++ LTE + L
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER----LSQELEYLTEDVKRLNEKL 152
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE------TDIN-ELRNSIKYLESVK 194
+ E+ LK + + ++S+K +L + E T +N EL+ L ++
Sbjct: 153 KESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALG 212
Query: 195 SEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA-R 253
E +L L N ++ + ++E+++ LK N++L + +
Sbjct: 213 REKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASME 272
Query: 254 DKFIANLE-EMK-TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+KF L +K + L + + + K + ++ L+ KL+ + E N+ +Q+ L
Sbjct: 273 EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELH-KLLKEAGEANKAIQDH---L 328
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLND----TENNSYKLIENMFNKVSQIAS----- 362
++ + ++ E+E+ EK +L +E ND T+ L E +S A+
Sbjct: 329 LEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKI 388
Query: 363 ---DFKISNQLSCELDDESENTYE-----RISLTLDKITNHI----TYLNTQINETQKND 410
K++ + ++ + + E RI+ LD+I + L Q E ++
Sbjct: 389 VKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQ 448
Query: 411 NAQL-----LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
A L +A K+I L E ++ S LE +N+ + I+++ + + + L+
Sbjct: 449 KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELE 508
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
++ S +I + + + +++++ +Q Q+ L
Sbjct: 509 EA--RGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLL 554
>U69668-1|AAB48030.1| 2363|Homo sapiens Tpr protein.
Length = 2363
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/448 (17%), Positives = 183/448 (40%), Gaps = 30/448 (6%)
Query: 80 LTEKLTIAETKHNDLK-KLYEDSASELEA------LKRENIQMHTSDVMVVPEIIDSLTE 132
L EKL + T +L+ KL E AS++ L++E +H+ + + E+ E
Sbjct: 148 LNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDE 207
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES 192
++ + E+ ++ KK +++ ++ ++ L T NE + + + L+
Sbjct: 208 LLALGREKGNEILELKCNLENKKEEVSR----LEEQMNGLKTSNEHLQKHVEDLLTKLKE 263
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
K + + EK +LN + N + D + ++ L + A
Sbjct: 264 AKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKA 323
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
+ +E+ K + +E L EK ++E++ N+ L +R+ +E+ +S
Sbjct: 324 IQDHLLEVEQSKDQMEKEML----EKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK-VSQIASDFKISNQLS 371
+ V K + + +LT L +T++ L+E + NK +++ + +
Sbjct: 380 PTAAAVAK----IVKPGMKLTELYNAYVETQDQ--LLLEKLENKRINKYLDEIVKEVEAK 433
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
+ YER + ++ + +I Q++ + +A KQ + L N
Sbjct: 434 APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTD-----KANKQSSVLERDNRR 488
Query: 432 LKERLSQLETENKELLIEIQTVRGSN--EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
++ ++ L + + LL+E++ RG++ + ++ D S+ N IE+++
Sbjct: 489 MEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRN-IEELQ 547
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+ +L + +++++E K
Sbjct: 548 QQNQRLLVALRELGETREREEQETTSSK 575
Score = 46.8 bits (106), Expect = 2e-04
Identities = 101/528 (19%), Positives = 219/528 (41%), Gaps = 55/528 (10%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
FK+ E+ Y EI + S Q+ + V + + E+ + QL
Sbjct: 46 FKVESEQQYFEIEKRLSHSQERL-VNETRECQSLRLELEKLNNQLKALTEK--------N 96
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L IA+ ++ ++ + + ELEA KR+ I+ + + + ++ LTE + L
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER----LSQELEYLTEDVKRLNEKL 152
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE------TDIN-ELRNSIKYLESVK 194
+ E+ LK + + ++S+K +L + E T +N EL+ L ++
Sbjct: 153 KESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALG 212
Query: 195 SEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA-R 253
E +L L N ++ + ++E+++ LK N++L + +
Sbjct: 213 REKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASME 272
Query: 254 DKFIANLE-EMK-TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+KF L +K + L + + + K + ++ L+ KL+ + E N+ +Q+ L
Sbjct: 273 EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELH-KLLKEAGEANKAIQDH---L 328
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLND----TENNSYKLIENMFNKVSQIAS----- 362
++ + ++ E+E+ EK +L +E ND T+ L E +S A+
Sbjct: 329 LEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKI 388
Query: 363 ---DFKISNQLSCELDDESENTYE-----RISLTLDKITNHI----TYLNTQINETQKND 410
K++ + ++ + + E RI+ LD+I + L Q E ++
Sbjct: 389 VKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQ 448
Query: 411 NAQL-----LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
A L +A K+I L E ++ S LE +N+ + I+++ + + + L+
Sbjct: 449 KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELE 508
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
++ S +I + + + +++++ +Q Q+ L
Sbjct: 509 EA--RGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLL 554
Score = 46.4 bits (105), Expect = 2e-04
Identities = 82/424 (19%), Positives = 171/424 (40%), Gaps = 29/424 (6%)
Query: 32 EIGQLKS-GLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXL--TEKLTIAE 88
E+ Q++S +Q V + ++ + EL+ D +N+ ++ + TE + +
Sbjct: 1215 EVAQVESLRYRQRVELLERELQELQ-DSLNAEREKVQVTAKTMAQHEELMKKTETMNVVM 1273
Query: 89 TKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVA 148
+ L++ E +L+ ++ + ++ D++ + E L+E L + LEE
Sbjct: 1274 ETNKMLREEKERLEQDLQQMQAK-VRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDV 1332
Query: 149 LEIDLKKNSITKDNISIKTL-LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
+ + T KL+++ E ++ + + +K+E +N L
Sbjct: 1333 KRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASL--- 1389
Query: 208 LNNAVDKQNCIQE-EVDLLKIENQN-LLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKT 265
NN QN IQ + DL K+ + +Q + K I KT
Sbjct: 1390 TNN----QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGR--RYKT 1443
Query: 266 MLVEEKLSEIKEKDENFKQEIDMLNEKL-ICDRREFNETMQEKNILLSDLSKKVNKTERE 324
E K + K + + + D + + + + +E ET+ + L +V ++
Sbjct: 1444 QYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKT 1503
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYER 384
L EK+ + +L EQ ++ +L +++ ++ +Q QL ++ ++ E T +
Sbjct: 1504 LSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQ-------EEQLRQQITEKEEKTRKA 1556
Query: 385 ISLTLDKITNHITYLNTQI---NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
I KI H+ + Q+ NE K N L + + +T + R+S+LE
Sbjct: 1557 IVAAKSKIA-HLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLER 1615
Query: 442 ENKE 445
E +E
Sbjct: 1616 ELRE 1619
Score = 46.0 bits (104), Expect = 3e-04
Identities = 61/331 (18%), Positives = 131/331 (39%), Gaps = 14/331 (4%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E ++ EL++S+ E K + E+L + N + E +L+ E + L Q
Sbjct: 1232 ERELQELQDSLN-AEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDL 1290
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTML-VEEKLSEIKEKDENFKQEIDMLNEKLIC 295
+ A L E ML E+KL E K + + +++++
Sbjct: 1291 QQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQ-HLVSQQKDP 1349
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
D E+ + + EK + +K++ + E+ + ++ L + +N L E++ N
Sbjct: 1350 DTEEYRKLLSEKEVH----TKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDL-N 1404
Query: 356 KVSQIASDFKISNQLSCELDD--ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQ 413
KV I L ++ D E T ++ + L Q ++ + +AQ
Sbjct: 1405 KVR--TEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMET-SAQ 1461
Query: 414 LLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
+ ++Q + E LKE L+Q ET++K L +++ ++ + E ++
Sbjct: 1462 SSGDHQEQHVSVQEMQE-LKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQ 1520
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDD 504
+++D T+ + + Q + ++
Sbjct: 1521 LQSELSRLRQDLQDRTTQEEQLRQQITEKEE 1551
Score = 36.7 bits (81), Expect = 0.20
Identities = 55/305 (18%), Positives = 125/305 (40%), Gaps = 32/305 (10%)
Query: 53 ELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKREN 112
E+ I + ++ LT + ++ DL K+ +E E ++++
Sbjct: 1362 EVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKV----RTEKETIQKD- 1416
Query: 113 IQMHTSDVMVVPEIIDSLTEVINTLTNGFESL---EEVALEIDLKKNSITKD-NISIKTL 168
+ D+ + I + ++ +E L ++ +E + + ++ ++S++ +
Sbjct: 1417 LDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEM 1476
Query: 169 --LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLK 226
L + + + ET L + ++ L+ SE T L EQ + + +++++
Sbjct: 1477 QELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRT 1536
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEI 286
+ + L Q ++ IA+L +K L +E E+K+++ Q+
Sbjct: 1537 TQEEQLRQQITEKEEKTRKAIVAAKSK---IAHLAGVKDQLTKEN-EELKQRNGALDQQK 1592
Query: 287 DMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNS 346
D L+ ++ L S ++++ EREL E QE+ HL EQ ++ + S
Sbjct: 1593 DELDVRITA--------------LKSQYEGRISRLERELREHQER--HL-EQRDEPQEPS 1635
Query: 347 YKLIE 351
K+ E
Sbjct: 1636 NKVPE 1640
Score = 36.3 bits (80), Expect = 0.26
Identities = 92/490 (18%), Positives = 194/490 (39%), Gaps = 38/490 (7%)
Query: 41 QQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKH-NDLKKLYE 99
+ N+ + K + + EI ++ R L T K + + +DL
Sbjct: 883 ETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLR 942
Query: 100 DSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSIT 159
+ ++ LK E ++ TS+V ++ SL E +N + EEV I+++
Sbjct: 943 QTEEQVNDLK-ERLKTSTSNVEQYQAMVTSLEESLNKEK---QVTEEVRKNIEVR----L 994
Query: 160 KDNISIKTLLDKLITKNETDINELRNSIKY-LESVKSEYNTANEKLFEQLNNAVDKQNCI 218
K++ +T L+K + + E + EL++ + +ES++ + + +K + N V Q +
Sbjct: 995 KESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSEL-KKTLSSVQNEV--QEAL 1051
Query: 219 QEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEK 278
Q L E Q A++E ++ +E++S++
Sbjct: 1052 QRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQA--AKEQVSKMA-- 1107
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSD-LSKKVNKTERELEEKQEQLTHLME 337
+ +Q ++ +K E + +E+ +L D +SK V + E +LE++ L +E
Sbjct: 1108 --SVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCE-DLEKQNRLLHDQIE 1164
Query: 338 QLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL-------DDESENTYERISLTLD 390
+L+D S K E + ++ S+ S + E+ + +E +E +
Sbjct: 1165 KLSDKVVASVK--EGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRFEVAQVESL 1222
Query: 391 KITNHITYLNTQINETQKNDNA-----QLLWEAKKQIADL---TEQNIILKERLSQLETE 442
+ + L ++ E Q + NA Q+ + Q +L TE ++ E L E
Sbjct: 1223 RYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREE 1282
Query: 443 NKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDL 502
+ L ++Q ++ ++ L++ E + ++ V WK++ + L
Sbjct: 1283 KERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQHL 1342
Query: 503 DDVMKQQQKE 512
K E
Sbjct: 1343 VSQQKDPDTE 1352
Score = 34.3 bits (75), Expect = 1.1
Identities = 64/359 (17%), Positives = 153/359 (42%), Gaps = 34/359 (9%)
Query: 125 EIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNIS-IKTLLDKLITKNETDINEL 183
E ++ L E + L + + L+ K+ + +DN+ + + L +N+
Sbjct: 695 EQLEKLQEQVTDLRSQNTKIS-TQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATT 753
Query: 184 RNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXX 243
+ + + ++ + ANEKL + +N +++E ++LK+ L Q
Sbjct: 754 QKQEQIINTMTQDLRGANEKLAVA---EIRAEN-LKKEKEMLKLSEVRLSQQRESLLAEQ 809
Query: 244 XXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
++ + NL+ ++ +L E +E K++ +I+ L ++ +++
Sbjct: 810 R-------GQNLLLTNLQTIQGIL-ERSETETKQR---LSSQIEKLEHEISHLKKKLENE 858
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+++++ L +L ++ T+R+L+ + + E L + + L ++ N Q+AS
Sbjct: 859 VEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKRHLSNMEVQVASQ 918
Query: 364 F-------KISNQLSC-ELDDESENTYERISLTLDKI---TNHITYLNTQIN--ETQKND 410
+ SN+ +L + T E+++ +++ T+++ + E N
Sbjct: 919 SSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNK 978
Query: 411 NAQLLWEAKKQI----ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
Q+ E +K I + E L+++L ++E E +EL + + S E+ LK
Sbjct: 979 EKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELK 1037
Score = 31.9 bits (69), Expect = 5.6
Identities = 79/406 (19%), Positives = 152/406 (37%), Gaps = 39/406 (9%)
Query: 10 ANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXX 69
A NE I+N +L+E ++ + + + K E+ D + R++
Sbjct: 687 AENEKIQN---EQLEKLQEQVTDLRSQNTKISTQLDFASKRY-EMLQDNVEGYRREITSL 742
Query: 70 XXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSA-SELEA--LKRENIQMHTSDVMVVPEI 126
++ I T DL+ E A +E+ A LK+E + S+V + +
Sbjct: 743 HERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEIRAENLKKEKEMLKLSEVRLSQQR 802
Query: 127 IDSLTEVI--NTLTNGFESLEEVA--LEIDLKK---NSITKDNISIKTLLDKLITKNETD 179
L E N L ++++ + E + K+ + I K I L KL + E
Sbjct: 803 ESLLAEQRGQNLLLTNLQTIQGILERSETETKQRLSSQIEKLEHEISHLKKKLENEVEQR 862
Query: 180 INELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLK--IENQNLLQXXX 237
RN L K + +T LN +N Q+E+ LK + N +
Sbjct: 863 HTLTRNLDVQLLDTKRQLDTETNL---HLNTKELLKNA-QKEIATLKRHLSNMEVQVASQ 918
Query: 238 XXXXXXXXXXXXXXARDKFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLIC 295
D ++ L + + + ++E+L E ++ + L E L
Sbjct: 919 SSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNK 978
Query: 296 DRREFNETMQEKNILLSD-------LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
+++ E + + L + L KK+ + E+E +E Q+ +E + + K
Sbjct: 979 EKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELKK 1038
Query: 349 LIENMFNKVSQI--ASDFKISNQLSCELD--------DESENTYER 384
+ ++ N+V + + +SN+ D E++N YER
Sbjct: 1039 TLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYER 1084
>U30872-1|AAA82935.1| 3113|Homo sapiens mitosin protein.
Length = 3113
Score = 54.4 bits (125), Expect = 9e-07
Identities = 98/522 (18%), Positives = 221/522 (42%), Gaps = 47/522 (9%)
Query: 8 LFANNENIRNIIHAFKIRLEECYKEI-GQLKSGLQQNVGVGDKTVAELKNDEINSMIRQL 66
L A N+ +RN I+ ++RL+ KE+ GQ+ + + + +K EL E ++ +
Sbjct: 283 LKAQNQELRNKINELELRLQGHEKEMKGQVNKFQELQLQL-EKAKVELIEKE--KVLNKC 339
Query: 67 XXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEI 126
+ K T E K LKKL ED + + + + + + E
Sbjct: 340 RDELVRTTAQYDQASTKYTALEQK---LKKLTEDLSCQRQNAESARCSLEQK----IKEK 392
Query: 127 IDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS 186
E ++ F++L++ +++ K +T++ K + + L + ++++L +
Sbjct: 393 EKEFQEELSRQQRSFQTLDQECIQM---KARLTQELQQAKNMHNVL----QAELDKLTSV 445
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
+ LE+ E+ + + + K+N ++ ++ +K EN NLL+
Sbjct: 446 KQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMKKEN-NLLKSHSEQKAREVCH 504
Query: 247 XXXXXARDKFIANLEEMKTMLVEEK--LSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
A L+ +K L + + E+K K+ + + + L EK+ +++E + T+
Sbjct: 505 LE---------AELKNIKQCLNQSQNFAEEMKAKNTSQETMLRDLQEKI--NQQENSLTL 553
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
++ + ++DL K+ + ++ L++++ + L ++L+ TE S L+ + K + +
Sbjct: 554 EKLKLAVADLEKQRDCSQDLLKKREHHIEQLNDKLSKTEKESKALLSALELKKKEY--EL 611
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNT-----QINETQKNDNAQLLWEAK 419
K L E+E ++ + + + I +L T QI + N+ + L +
Sbjct: 612 KEEKTLFSCWKSENEKLLTQMESEKENLQSKINHLETCLKTQQIKSHEYNERVRTLEMDR 671
Query: 420 KQIA-DLTEQNIILKERLSQLETENKELL-----IEIQTVRGSNEEVTLNLKDSSTX--X 471
+ ++ ++ + +L + ++ET+ + E + E + LK S
Sbjct: 672 ENLSVEIRNLHNVLDSKSVEVETQKLAYMELQQKAEFSDQKHQKEIENMCLKTSQLTGQV 731
Query: 472 XXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
SNEI D + +++E L D++K + L
Sbjct: 732 EDLEHKLQLLSNEIMDKDRCYQDLHAEYESLRDLLKSKDASL 773
Score = 52.0 bits (119), Expect = 5e-06
Identities = 101/520 (19%), Positives = 222/520 (42%), Gaps = 47/520 (9%)
Query: 11 NNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVA-ELKNDEINSMIRQLXXX 69
+NEN + +I + L E QL+ L + KT A + ++++ ++L
Sbjct: 1937 DNENKQKVIVCLEEELSVVTSERNQLRGELDT---MSKKTTALDQLSEKMKEKTQELESH 1993
Query: 70 XXX----XXXXXXXLTEKLTIAETKHNDLKKLYEDSA---SELEALKRENIQMHTSDVMV 122
+ EK + +T +D+ +L +D +L++L++++ + + +
Sbjct: 1994 QSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKDSQALSLTKCEL 2053
Query: 123 VPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKD---NISIKTLLDKLITKNETD 179
+I L + L ESL+ E D +K +++K + K ++ + +
Sbjct: 2054 ENQIAQ-LNKEKELLVKESESLQARLSESDYEKLNVSKALEAALVEKGEFALRLSSTQEE 2112
Query: 180 INELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXX 239
+++LR I+ L V+ E A+EK +QL+ A +K + E D LK + +NL +
Sbjct: 2113 VHQLRRGIEKLR-VRIE---ADEK--KQLHIA-EKLKERERENDSLKDKVENLERELQMS 2165
Query: 240 XXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDRR 298
++ I + E K VE ++I+E + K E+D++ L ++
Sbjct: 2166 EEN----------QELVILDAENSKAE-VETLKTQIEEMARSLKVFELDLVT--LRSEKE 2212
Query: 299 EFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
+ +QEK LS+L K ++ + LEEK++ + E+ ++ + V+
Sbjct: 2213 NLTKQIQEKQGQLSELDKLLSSFKSLLEEKEQAEIQIKEESKTAVEMLQNQLKELNEAVA 2272
Query: 359 QIASDFKISNQLSCELDDESE------NTYERISLTLDKITNHITYLNTQINETQKNDNA 412
+ D +I LD E N+ E++ L+ + Q+ E++ +A
Sbjct: 2273 ALCGDQEIMKATEQSLDPPIEEEHQLRNSIEKLRARLEADEKKQLCVLQQLKESE--HHA 2330
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
LL K ++ +L + I + E + E++T++ E +T +L+
Sbjct: 2331 DLL---KGRVENLERELEIARTNQEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVV 2387
Query: 473 XXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+NE++ + ++ E + +++++++++E
Sbjct: 2388 TIRSEKENLTNELQKEQERISELEIINSSFENILQEKEQE 2427
Score = 50.0 bits (114), Expect = 2e-05
Identities = 65/285 (22%), Positives = 124/285 (43%), Gaps = 34/285 (11%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD--- 313
I+ L+E T + ++E EN ++E+ +LN+K+ ++ E E +++ N LL D
Sbjct: 884 ISKLQE-DTSAHQNVVAETLSALENKEKELQLLNDKVETEQAEIQE-LKKSNHLLEDSLK 941
Query: 314 ----------LSKK-----VNKTERELEEKQEQ---LTHLMEQLNDTENNSYKLIENMFN 355
L KK ++ +RE+EE ++ L + LN + N + E+ N
Sbjct: 942 ELQLLSETLSLEKKEMSSIISLNKREIEELTQENGTLKEINASLNQEKMNLIQKSESFAN 1001
Query: 356 -------KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINE-TQ 407
+S+++ +K + + +E+ N YE +S + L +NE T
Sbjct: 1002 YIDEREKSISELSDQYKQEKLILLQRCEETGNAYEDLSQKYKAAQEKNSKLECLLNECTS 1061
Query: 408 KNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS-NEEVTLNLKD 466
+N + E K+ Q + K L+ E N+ L++E++TV+ + E+T N +
Sbjct: 1062 LCENRKNELEQLKEAFAKEHQEFLTK--LAFAEERNQNLMLELETVQQALRSEMTDNQNN 1119
Query: 467 SSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
S + E M+ +V + + E L VMK + +
Sbjct: 1120 SKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHE 1164
Score = 49.2 bits (112), Expect = 3e-05
Identities = 86/416 (20%), Positives = 176/416 (42%), Gaps = 46/416 (11%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELE------ALKRENIQMHTSDVMVVPEIIDS-LTE 132
L E ++ E + N+L++L E A E + A E Q ++ V + + S +T+
Sbjct: 1056 LNECTSLCENRKNELEQLKEAFAKEHQEFLTKLAFAEERNQNLMLELETVQQALRSEMTD 1115
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISI----KTLLDKLITKNETDINE---LRN 185
N + L++ + + ++N + K+ + + L+ + TK+E E +RN
Sbjct: 1116 NQNNSKSEAGGLKQEIMTLKEEQNKMQKEVNDLLQENEQLMKVMKTKHECQNLESEPIRN 1175
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
S+K ES +++ N + E ++D N +++ + + N+ L
Sbjct: 1176 SVKERESERNQCNFKPQMDLEVKEISLDSYNAQLVQLEAM-LRNKELKLQESEKEKECLQ 1234
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQ 305
D +NL++M++ +++S +K+ EID EK I E + +
Sbjct: 1235 HELQTIRGDLETSNLQDMQS----QEISGLKDC------EIDA-EEKYISGPHELSTSQN 1283
Query: 306 EKNILLSDLS---KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
+ L L K+N+ E+ E Q + L+ +LND+ + M +V ++ +
Sbjct: 1284 DNAHLQCSLQTTMNKLNELEKICEILQAEKYELVTELNDSRSECITATRKMAEEVGKLLN 1343
Query: 363 DFKISNQ----LSCELDD--------ESENTYERISLTLDKITNHITYLNTQINETQKND 410
+ KI N L EL + E N +SL +N +L E Q +
Sbjct: 1344 EVKILNDDSGLLHGELVEDIPGGEFGEQPNEQHPVSLAPLDESNSYEHLTLSDKEVQMH- 1402
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
E +++ L ++ IL ++ Q+ ++ EL + +++ N ++ NL++
Sbjct: 1403 ----FAELQEKFLSLQSEHKILHDQHCQMSSKMSELQTYVDSLKAENLVLSTNLRN 1454
Score = 45.2 bits (102), Expect = 6e-04
Identities = 52/264 (19%), Positives = 117/264 (44%), Gaps = 20/264 (7%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNE------TMQEKNILL 311
A+LE ++T EKL +++ +EN ++ I L E+L E N+ TM +K L
Sbjct: 1922 ADLEVVQT----EKLC-LEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTAL 1976
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
LS+K+ + +ELE Q + H ++ +L++ + + VS++ D +
Sbjct: 1977 DQLSEKMKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKL 2036
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
L+ +S + +SLT ++ N I LN + E ++ L +A+ +D + N+
Sbjct: 2037 QSLEKDS----QALSLTKCELENQIAQLNKE-KELLVKESESL--QARLSESDYEKLNV- 2088
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
+ L E E + + + + ++ ++ + ++++ + +
Sbjct: 2089 -SKALEAALVEKGEFALRLSSTQEEVHQLRRGIEKLRVRIEADEKKQLHIAEKLKERERE 2147
Query: 492 VMEWKSQFEDLDDVMKQQQKELKL 515
K + E+L+ ++ ++ +L
Sbjct: 2148 NDSLKDKVENLERELQMSEENQEL 2171
Score = 43.2 bits (97), Expect = 0.002
Identities = 56/264 (21%), Positives = 111/264 (42%), Gaps = 15/264 (5%)
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL---ICDRREFNETMQEKNILLSDLS 315
+L+E++ M E E+++ K+E L+EKL CD +E + ++ L SDL
Sbjct: 1811 HLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQELLQRVETSEGLNSDLE 1870
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+K+ R E + + ++ND+ + +EN +++ + + L E D
Sbjct: 1871 MHADKSSR------EDIGDNVAKVNDSWKERFLDVENELSRIRSEKASIE-HEALYLEAD 1923
Query: 376 DESENTYERISLTLDKITNH--ITYLNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNII 431
E T E++ L D I L +++ +++N L K+ L + +
Sbjct: 1924 LEVVQT-EKLCLEKDNENKQKVIVCLEEELSVVTSERNQLRGELDTMSKKTTALDQLSEK 1982
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
+KE+ +LE+ E L IQ +E T L+ S+ +++ ++
Sbjct: 1983 MKEKTQELESHQSECLHCIQVAEAEVKEKTELLQTLSSDVSELLKDKTHLQEKLQSLEKD 2042
Query: 492 VMEWKSQFEDLDDVMKQQQKELKL 515
+L++ + Q KE +L
Sbjct: 2043 SQALSLTKCELENQIAQLNKEKEL 2066
Score = 42.7 bits (96), Expect = 0.003
Identities = 87/485 (17%), Positives = 188/485 (38%), Gaps = 21/485 (4%)
Query: 35 QLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDL 94
Q + L+ G+ + K + + +R L LT +L + + ++L
Sbjct: 2351 QEHAALEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKENLTNELQKEQERISEL 2410
Query: 95 KKLYEDSASELEALKRENIQMH--TSDVMVVPEI-IDSLTEVINTLTNGFESLEEVALEI 151
+ + + L+ ++E +QM +S M + + + L E + L N E+ + +
Sbjct: 2411 EIINSSFENILQEKEQEKVQMKEKSSTAMEMLQTQLKELNERVAALHNDQEACKAKEQNL 2470
Query: 152 DLKKNSITKDNISIKTLLDK-----LITKNETD--INELRNSIKYLESVKSEYNTANEKL 204
+ + + + LD+ ++ ++ + I E+ + + LE E + ++
Sbjct: 2471 SSQVECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQI 2530
Query: 205 FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMK 264
+Q V K + ++ E L K +N L + + L+
Sbjct: 2531 QDQ-EQLVSKLSQVEGEHQLWKEQNLELRNLTVELEQKIQVLQSKNASLQDTLEVLQSSY 2589
Query: 265 TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L E +L K +F ++++ + K +RE +E Q+ L +LS + N+ E
Sbjct: 2590 KNL-ENELELTKMDKMSFVEKVNKMTAKETELQREMHEMAQKTAELQEELSGEKNRLAGE 2648
Query: 325 LEEKQEQLTHLMEQLND--TENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
L+ E++ +QL + EN+ K + +K Q+ + K+ +++ E
Sbjct: 2649 LQLLLEEIKSSKDQLKELTLENSELKKSLDCMHK-DQVEKEGKVREEIAEYQLRLHEAEK 2707
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
+ +L LD TN + Q + + L K +I DL + + KE L+
Sbjct: 2708 KHQALLLD--TNKQYEVEIQTYREKLTSKEECLSSQKLEI-DLLKSS---KEELNNSLKA 2761
Query: 443 NKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDL 502
++L E++ + N + LK + ++E+ K + + SQ +
Sbjct: 2762 TTQILEELKKTKMDNLKYVNQLKKENERAQGKMKLLIKSCKQLEEEKEILQKELSQLQAA 2821
Query: 503 DDVMK 507
+ K
Sbjct: 2822 QEKQK 2826
Score = 37.1 bits (82), Expect = 0.15
Identities = 28/127 (22%), Positives = 62/127 (48%), Gaps = 16/127 (12%)
Query: 389 LDKITNHITYLNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++ + N + L+++++ E Q + E +K + +L ++N L E+L +++EL
Sbjct: 1796 VESLLNEMKELDSKLHLQEVQLMTKIEACIELEKIVGELKKENSDLSEKLEYFSCDHQEL 1855
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME-WKSQFEDLDDV 505
L ++T G N ++ ++ SS +I D KV + WK +F D+++
Sbjct: 1856 LQRVETSEGLNSDLEMHADKSS-------------REDIGDNVAKVNDSWKERFLDVENE 1902
Query: 506 MKQQQKE 512
+ + + E
Sbjct: 1903 LSRIRSE 1909
Score = 33.5 bits (73), Expect = 1.8
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 4/93 (4%)
Query: 284 QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ-LNDT 342
+E++ L E + E M+ + I+ + K++ + E+ L ++++L L +Q L++
Sbjct: 1549 EELESLCEVYRQSLEKLEEKMESQGIMKN---KEIQELEQLLSSERQELDCLRKQYLSEN 1605
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
E KL S++A++ K + QLS EL+
Sbjct: 1606 EQWQQKLTSVTLEMESKLAAEKKQTEQLSLELE 1638
Score = 33.1 bits (72), Expect = 2.4
Identities = 37/196 (18%), Positives = 76/196 (38%), Gaps = 3/196 (1%)
Query: 325 LEEKQEQLTH-LMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
LE+K ++LT L Q + E+ L + + K + + + LD E
Sbjct: 360 LEQKLKKLTEDLSCQRQNAESARCSLEQKIKEKEKEFQEELSRQQRSFQTLDQECIQMKA 419
Query: 384 RISLTLDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
R++ L + N L ++++ + K L E K+++ + + + ++L
Sbjct: 420 RLTQELQQAKNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRR 479
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+E+ E ++ +E+ + N E+MK K ++ D
Sbjct: 480 SMEEMKKENNLLKSHSEQKAREVCHLEAELKNIKQCLNQSQNFAEEMKAKNTSQETMLRD 539
Query: 502 LDDVMKQQQKELKLGK 517
L + + QQ+ L L K
Sbjct: 540 LQEKINQQENSLTLEK 555
Score = 32.3 bits (70), Expect = 4.2
Identities = 20/93 (21%), Positives = 46/93 (49%), Gaps = 1/93 (1%)
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+K+ + E +L++ +++ QL+ E K + + N+ ++ ++ K NQ E+
Sbjct: 18 QKIQELEGQLDKLKKEKQQRQFQLDSLEAAPQKQTQKVENEKTE-GTNLKRENQRLMEIC 76
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQK 408
+ E T ++IS L + + + Q+N +K
Sbjct: 77 ESLEKTKQKISHELQVKESQVNFQEGQLNSGKK 109
Score = 31.5 bits (68), Expect = 7.4
Identities = 30/156 (19%), Positives = 66/156 (42%), Gaps = 6/156 (3%)
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
T + L L AV C +EV ++ +NL + + +
Sbjct: 1502 TGDMSLLSNLEGAVSANQCSVDEVFCSSLQEENLTRKETPSAPAKGVEELESLC-EVYRQ 1560
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF---NETMQEK-NILLSDL 314
+LE+++ + + + + KE E +Q + ++L C R+++ NE Q+K + ++
Sbjct: 1561 SLEKLEEKMESQGIMKNKEIQE-LEQLLSSERQELDCLRKQYLSENEQWQQKLTSVTLEM 1619
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLI 350
K+ +++ E+ +L QL + +S L+
Sbjct: 1620 ESKLAAEKKQTEQLSLELEVARLQLQGLDLSSRSLL 1655
>L01042-1|AAD54608.1| 1093|Homo sapiens TATA element modulatory
factor protein.
Length = 1093
Score = 54.4 bits (125), Expect = 9e-07
Identities = 91/479 (18%), Positives = 200/479 (41%), Gaps = 41/479 (8%)
Query: 48 DKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEA 107
+K + E D + + ++ T+++ AE K K + + E++
Sbjct: 471 EKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKN 530
Query: 108 LKRE-NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE---IDLKKNSITKDNI 163
+K E ++++S+ +++ E I L E L + L I K + K+N
Sbjct: 531 IKEELATRLNSSETA---DLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENE 587
Query: 164 SIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVD 223
++ L+K + + E ++ L+ + E V+ ++ +KL + +Q ++D
Sbjct: 588 NMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMD 647
Query: 224 LLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFK 283
L+ +N+++ A+D + M +E+LS EK +
Sbjct: 648 ELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQE-- 705
Query: 284 QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTH----LMEQL 339
+ R+ ET+ I + DL + +TE+ K++ L H L ++L
Sbjct: 706 ------------EARQQQETLA---IQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRL 750
Query: 340 NDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL-DKITNHITY 398
+ EN + +L +++ + + +I N L L ++ +++E++ L D++ T
Sbjct: 751 QEAENRNQELSQSVSSTTRPLLR--QIEN-LQATLGSQT-SSWEKLEKNLSDRLGESQTL 806
Query: 399 LNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS----QLETENKELLIEIQTVR 454
L + E ++ +LL K Q++ + QN +L++ S QLE+E K L +++
Sbjct: 807 LAAAV-ERERAATEELL-ANKIQMSSMESQNSLLRQENSRFQAQLESE-KNRLCKLEDEN 863
Query: 455 GSNEEVTLNLKDSSTXXXXXXXXXXXXSN-EIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+ NLKD N ++E + KV + + + + +K+++++
Sbjct: 864 NRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKERK 922
>BC126123-1|AAI26124.1| 1093|Homo sapiens TATA element modulatory
factor 1 protein.
Length = 1093
Score = 54.4 bits (125), Expect = 9e-07
Identities = 91/479 (18%), Positives = 200/479 (41%), Gaps = 41/479 (8%)
Query: 48 DKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEA 107
+K + E D + + ++ T+++ AE K K + + E++
Sbjct: 471 EKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKN 530
Query: 108 LKRE-NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE---IDLKKNSITKDNI 163
+K E ++++S+ +++ E I L E L + L I K + K+N
Sbjct: 531 IKEELATRLNSSETA---DLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENE 587
Query: 164 SIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVD 223
++ L+K + + E ++ L+ + E V+ ++ +KL + +Q ++D
Sbjct: 588 NMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMD 647
Query: 224 LLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFK 283
L+ +N+++ A+D + M +E+LS EK +
Sbjct: 648 ELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQE-- 705
Query: 284 QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTH----LMEQL 339
+ R+ ET+ I + DL + +TE+ K++ L H L ++L
Sbjct: 706 ------------EARQQQETLA---IQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRL 750
Query: 340 NDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL-DKITNHITY 398
+ EN + +L +++ + + +I N L L ++ +++E++ L D++ T
Sbjct: 751 QEAENRNQELSQSVSSTTRPLLR--QIEN-LQATLGSQT-SSWEKLEKNLSDRLGESQTL 806
Query: 399 LNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS----QLETENKELLIEIQTVR 454
L + E ++ +LL K Q++ + QN +L++ S QLE+E K L +++
Sbjct: 807 LAAAV-ERERAATEELL-ANKIQMSSMESQNSLLRQENSRFQAQLESE-KNRLCKLEDEN 863
Query: 455 GSNEEVTLNLKDSSTXXXXXXXXXXXXSN-EIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+ NLKD N ++E + KV + + + + +K+++++
Sbjct: 864 NRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKERK 922
>BC117418-1|AAI17419.1| 1093|Homo sapiens TATA element modulatory
factor 1 protein.
Length = 1093
Score = 54.4 bits (125), Expect = 9e-07
Identities = 91/479 (18%), Positives = 200/479 (41%), Gaps = 41/479 (8%)
Query: 48 DKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEA 107
+K + E D + + ++ T+++ AE K K + + E++
Sbjct: 471 EKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKN 530
Query: 108 LKRE-NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE---IDLKKNSITKDNI 163
+K E ++++S+ +++ E I L E L + L I K + K+N
Sbjct: 531 IKEELATRLNSSETA---DLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENE 587
Query: 164 SIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVD 223
++ L+K + + E ++ L+ + E V+ ++ +KL + +Q ++D
Sbjct: 588 NMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMD 647
Query: 224 LLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFK 283
L+ +N+++ A+D + M +E+LS EK +
Sbjct: 648 ELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQE-- 705
Query: 284 QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTH----LMEQL 339
+ R+ ET+ I + DL + +TE+ K++ L H L ++L
Sbjct: 706 ------------EARQQQETLA---IQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRL 750
Query: 340 NDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL-DKITNHITY 398
+ EN + +L +++ + + +I N L L ++ +++E++ L D++ T
Sbjct: 751 QEAENRNQELSQSVSSTTRPLLR--QIEN-LQATLGSQT-SSWEKLEKNLSDRLGESQTL 806
Query: 399 LNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS----QLETENKELLIEIQTVR 454
L + E ++ +LL K Q++ + QN +L++ S QLE+E K L +++
Sbjct: 807 LAAAV-ERERAATEELL-ANKIQMSSMESQNSLLRQENSRFQAQLESE-KNRLCKLEDEN 863
Query: 455 GSNEEVTLNLKDSSTXXXXXXXXXXXXSN-EIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+ NLKD N ++E + KV + + + + +K+++++
Sbjct: 864 NRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKERK 922
>BC094764-1|AAH94764.1| 692|Homo sapiens TPR protein protein.
Length = 692
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/448 (17%), Positives = 183/448 (40%), Gaps = 30/448 (6%)
Query: 80 LTEKLTIAETKHNDLK-KLYEDSASELEA------LKRENIQMHTSDVMVVPEIIDSLTE 132
L EKL + T +L+ KL E AS++ L++E +H+ + + E+ E
Sbjct: 148 LNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDE 207
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES 192
++ + E+ ++ KK +++ ++ ++ L T NE + + + L+
Sbjct: 208 LLALGREKGNEILELKCNLENKKEEVSR----LEEQMNGLKTSNEHLQKHVEDLLTKLKE 263
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
K + + EK +LN + N + D + ++ L + A
Sbjct: 264 AKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKA 323
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
+ +E+ K + +E L EK ++E++ N+ L +R+ +E+ +S
Sbjct: 324 IQDHLLEVEQSKDQMEKEML----EKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK-VSQIASDFKISNQLS 371
+ V K + + +LT L +T++ L+E + NK +++ + +
Sbjct: 380 PTAAAVAK----IVKPGMKLTELYNAYVETQDQ--LLLEKLENKRINKYLDEIVKEVEAK 433
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
+ YER + ++ + +I Q++ + +A KQ + L N
Sbjct: 434 APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTD-----KANKQSSVLERDNRR 488
Query: 432 LKERLSQLETENKELLIEIQTVRGSN--EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
++ ++ L + + LL+E++ RG++ + ++ D S+ N IE+++
Sbjct: 489 MEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRN-IEELQ 547
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+ +L + +++++E K
Sbjct: 548 QQNQRLLVALRELGETREREEQETTSSK 575
Score = 46.8 bits (106), Expect = 2e-04
Identities = 101/528 (19%), Positives = 219/528 (41%), Gaps = 55/528 (10%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
FK+ E+ Y EI + S Q+ + V + + E+ + QL
Sbjct: 46 FKVESEQQYFEIEKRLSHSQERL-VNETRECQSLRLELEKLNNQLKALTEK--------N 96
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L IA+ ++ ++ + + ELEA KR+ I+ + + + ++ LTE + L
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER----LSQELEYLTEDVKRLNEKL 152
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE------TDIN-ELRNSIKYLESVK 194
+ E+ LK + + ++S+K +L + E T +N EL+ L ++
Sbjct: 153 KESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALG 212
Query: 195 SEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA-R 253
E +L L N ++ + ++E+++ LK N++L + +
Sbjct: 213 REKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASME 272
Query: 254 DKFIANLE-EMK-TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+KF L +K + L + + + K + ++ L+ KL+ + E N+ +Q+ L
Sbjct: 273 EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELH-KLLKEAGEANKAIQDH---L 328
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLND----TENNSYKLIENMFNKVSQIAS----- 362
++ + ++ E+E+ EK +L +E ND T+ L E +S A+
Sbjct: 329 LEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKI 388
Query: 363 ---DFKISNQLSCELDDESENTYE-----RISLTLDKITNHI----TYLNTQINETQKND 410
K++ + ++ + + E RI+ LD+I + L Q E ++
Sbjct: 389 VKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQ 448
Query: 411 NAQL-----LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
A L +A K+I L E ++ S LE +N+ + I+++ + + + L+
Sbjct: 449 KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELE 508
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
++ S +I + + + +++++ +Q Q+ L
Sbjct: 509 EA--RGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLL 554
>BC016514-1|AAH16514.1| 687|Homo sapiens TPR protein protein.
Length = 687
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/448 (17%), Positives = 183/448 (40%), Gaps = 30/448 (6%)
Query: 80 LTEKLTIAETKHNDLK-KLYEDSASELEA------LKRENIQMHTSDVMVVPEIIDSLTE 132
L EKL + T +L+ KL E AS++ L++E +H+ + + E+ E
Sbjct: 148 LNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDE 207
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES 192
++ + E+ ++ KK +++ ++ ++ L T NE + + + L+
Sbjct: 208 LLALGREKGNEILELKCNLENKKEEVSR----LEEQMNGLKTSNEHLQKHVEDLLTKLKE 263
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
K + + EK +LN + N + D + ++ L + A
Sbjct: 264 AKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKA 323
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
+ +E+ K + +E L EK ++E++ N+ L +R+ +E+ +S
Sbjct: 324 IQDHLLEVEQSKDQMEKEML----EKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK-VSQIASDFKISNQLS 371
+ V K + + +LT L +T++ L+E + NK +++ + +
Sbjct: 380 PTAAAVAK----IVKPGMKLTELYNAYVETQDQ--LLLEKLENKRINKYLDEIVKEVEAK 433
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
+ YER + ++ + +I Q++ + +A KQ + L N
Sbjct: 434 APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTD-----KANKQSSVLERDNRR 488
Query: 432 LKERLSQLETENKELLIEIQTVRGSN--EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
++ ++ L + + LL+E++ RG++ + ++ D S+ N IE+++
Sbjct: 489 MEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRN-IEELQ 547
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+ +L + +++++E K
Sbjct: 548 QQNQRLLVALRELGETREREEQETTSSK 575
Score = 46.8 bits (106), Expect = 2e-04
Identities = 101/528 (19%), Positives = 219/528 (41%), Gaps = 55/528 (10%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
FK+ E+ Y EI + S Q+ + V + + E+ + QL
Sbjct: 46 FKVESEQQYFEIEKRLSHSQERL-VNETRECQSLRLELEKLNNQLKALTEK--------N 96
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L IA+ ++ ++ + + ELEA KR+ I+ + + + ++ LTE + L
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER----LSQELEYLTEDVKRLNEKL 152
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE------TDIN-ELRNSIKYLESVK 194
+ E+ LK + + ++S+K +L + E T +N EL+ L ++
Sbjct: 153 KESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALG 212
Query: 195 SEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA-R 253
E +L L N ++ + ++E+++ LK N++L + +
Sbjct: 213 REKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASME 272
Query: 254 DKFIANLE-EMK-TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+KF L +K + L + + + K + ++ L+ KL+ + E N+ +Q+ L
Sbjct: 273 EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELH-KLLKEAGEANKAIQDH---L 328
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLND----TENNSYKLIENMFNKVSQIAS----- 362
++ + ++ E+E+ EK +L +E ND T+ L E +S A+
Sbjct: 329 LEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKI 388
Query: 363 ---DFKISNQLSCELDDESENTYE-----RISLTLDKITNHI----TYLNTQINETQKND 410
K++ + ++ + + E RI+ LD+I + L Q E ++
Sbjct: 389 VKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQ 448
Query: 411 NAQL-----LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
A L +A K+I L E ++ S LE +N+ + I+++ + + + L+
Sbjct: 449 KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELE 508
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
++ S +I + + + +++++ +Q Q+ L
Sbjct: 509 EA--RGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLL 554
>AL596220-1|CAI13119.1| 2363|Homo sapiens translocated promoter
region (to activated MET oncogene) protein.
Length = 2363
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/448 (17%), Positives = 183/448 (40%), Gaps = 30/448 (6%)
Query: 80 LTEKLTIAETKHNDLK-KLYEDSASELEA------LKRENIQMHTSDVMVVPEIIDSLTE 132
L EKL + T +L+ KL E AS++ L++E +H+ + + E+ E
Sbjct: 148 LNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDE 207
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES 192
++ + E+ ++ KK +++ ++ ++ L T NE + + + L+
Sbjct: 208 LLALGREKGNEILELKCNLENKKEEVSR----LEEQMNGLKTSNEHLQKHVEDLLTKLKE 263
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
K + + EK +LN + N + D + ++ L + A
Sbjct: 264 AKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKA 323
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
+ +E+ K + +E L EK ++E++ N+ L +R+ +E+ +S
Sbjct: 324 IQDHLLEVEQSKDQMEKEML----EKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK-VSQIASDFKISNQLS 371
+ V K + + +LT L +T++ L+E + NK +++ + +
Sbjct: 380 PTAAAVAK----IVKPGMKLTELYNAYVETQDQ--LLLEKLENKRINKYLDEIVKEVEAK 433
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
+ YER + ++ + +I Q++ + +A KQ + L N
Sbjct: 434 APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTD-----KANKQSSVLERDNRR 488
Query: 432 LKERLSQLETENKELLIEIQTVRGSN--EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
++ ++ L + + LL+E++ RG++ + ++ D S+ N IE+++
Sbjct: 489 MEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRN-IEELQ 547
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+ +L + +++++E K
Sbjct: 548 QQNQRLLVALRELGETREREEQETTSSK 575
Score = 46.8 bits (106), Expect = 2e-04
Identities = 101/528 (19%), Positives = 219/528 (41%), Gaps = 55/528 (10%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
FK+ E+ Y EI + S Q+ + V + + E+ + QL
Sbjct: 46 FKVESEQQYFEIEKRLSHSQERL-VNETRECQSLRLELEKLNNQLKALTEK--------N 96
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L IA+ ++ ++ + + ELEA KR+ I+ + + + ++ LTE + L
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER----LSQELEYLTEDVKRLNEKL 152
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE------TDIN-ELRNSIKYLESVK 194
+ E+ LK + + ++S+K +L + E T +N EL+ L ++
Sbjct: 153 KESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALG 212
Query: 195 SEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA-R 253
E +L L N ++ + ++E+++ LK N++L + +
Sbjct: 213 REKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASME 272
Query: 254 DKFIANLE-EMK-TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+KF L +K + L + + + K + ++ L+ KL+ + E N+ +Q+ L
Sbjct: 273 EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELH-KLLKEAGEANKAIQDH---L 328
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLND----TENNSYKLIENMFNKVSQIAS----- 362
++ + ++ E+E+ EK +L +E ND T+ L E +S A+
Sbjct: 329 LEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKI 388
Query: 363 ---DFKISNQLSCELDDESENTYE-----RISLTLDKITNHI----TYLNTQINETQKND 410
K++ + ++ + + E RI+ LD+I + L Q E ++
Sbjct: 389 VKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQ 448
Query: 411 NAQL-----LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
A L +A K+I L E ++ S LE +N+ + I+++ + + + L+
Sbjct: 449 KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELE 508
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
++ S +I + + + +++++ +Q Q+ L
Sbjct: 509 EA--RGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLL 554
Score = 46.4 bits (105), Expect = 2e-04
Identities = 82/424 (19%), Positives = 171/424 (40%), Gaps = 29/424 (6%)
Query: 32 EIGQLKS-GLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXL--TEKLTIAE 88
E+ Q++S +Q V + ++ + EL+ D +N+ ++ + TE + +
Sbjct: 1215 EVAQVESLRYRQRVELLERELQELQ-DSLNAEREKVQVTAKTMAQHEELMKKTETMNVVM 1273
Query: 89 TKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVA 148
+ L++ E +L+ ++ + ++ D++ + E L+E L + LEE
Sbjct: 1274 ETNKMLREEKERLEQDLQQMQAK-VRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDV 1332
Query: 149 LEIDLKKNSITKDNISIKTL-LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
+ + T KL+++ E ++ + + +K+E +N L
Sbjct: 1333 KRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASL--- 1389
Query: 208 LNNAVDKQNCIQE-EVDLLKIENQN-LLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKT 265
NN QN IQ + DL K+ + +Q + K I KT
Sbjct: 1390 TNN----QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGR--RYKT 1443
Query: 266 MLVEEKLSEIKEKDENFKQEIDMLNEKL-ICDRREFNETMQEKNILLSDLSKKVNKTERE 324
E K + K + + + D + + + + +E ET+ + L +V ++
Sbjct: 1444 QYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKT 1503
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYER 384
L EK+ + +L EQ ++ +L +++ ++ +Q QL ++ ++ E T +
Sbjct: 1504 LSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQ-------EEQLRQQITEKEEKTRKA 1556
Query: 385 ISLTLDKITNHITYLNTQI---NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
I KI H+ + Q+ NE K N L + + +T + R+S+LE
Sbjct: 1557 IVAAKSKIA-HLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLER 1615
Query: 442 ENKE 445
E +E
Sbjct: 1616 ELRE 1619
Score = 46.0 bits (104), Expect = 3e-04
Identities = 61/331 (18%), Positives = 131/331 (39%), Gaps = 14/331 (4%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E ++ EL++S+ E K + E+L + N + E +L+ E + L Q
Sbjct: 1232 ERELQELQDSLN-AEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDL 1290
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTML-VEEKLSEIKEKDENFKQEIDMLNEKLIC 295
+ A L E ML E+KL E K + + +++++
Sbjct: 1291 QQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQ-HLVSQQKDP 1349
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
D E+ + + EK + +K++ + E+ + ++ L + +N L E++ N
Sbjct: 1350 DTEEYRKLLSEKEVH----TKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDL-N 1404
Query: 356 KVSQIASDFKISNQLSCELDD--ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQ 413
KV I L ++ D E T ++ + L Q ++ + +AQ
Sbjct: 1405 KVR--TEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMET-SAQ 1461
Query: 414 LLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
+ ++Q + E LKE L+Q ET++K L +++ ++ + E ++
Sbjct: 1462 SSGDHQEQHVSVQEMQE-LKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQ 1520
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDD 504
+++D T+ + + Q + ++
Sbjct: 1521 LQSELSRLRQDLQDRTTQEEQLRQQITEKEE 1551
Score = 36.7 bits (81), Expect = 0.20
Identities = 55/305 (18%), Positives = 125/305 (40%), Gaps = 32/305 (10%)
Query: 53 ELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKREN 112
E+ I + ++ LT + ++ DL K+ +E E ++++
Sbjct: 1362 EVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKV----RTEKETIQKD- 1416
Query: 113 IQMHTSDVMVVPEIIDSLTEVINTLTNGFESL---EEVALEIDLKKNSITKD-NISIKTL 168
+ D+ + I + ++ +E L ++ +E + + ++ ++S++ +
Sbjct: 1417 LDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEM 1476
Query: 169 --LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLK 226
L + + + ET L + ++ L+ SE T L EQ + + +++++
Sbjct: 1477 QELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRT 1536
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEI 286
+ + L Q ++ IA+L +K L +E E+K+++ Q+
Sbjct: 1537 TQEEQLRQQITEKEEKTRKAIVAAKSK---IAHLAGVKDQLTKEN-EELKQRNGALDQQK 1592
Query: 287 DMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNS 346
D L+ ++ L S ++++ EREL E QE+ HL EQ ++ + S
Sbjct: 1593 DELDVRITA--------------LKSQYEGRISRLERELREHQER--HL-EQRDEPQEPS 1635
Query: 347 YKLIE 351
K+ E
Sbjct: 1636 NKVPE 1640
Score = 35.9 bits (79), Expect = 0.34
Identities = 84/438 (19%), Positives = 177/438 (40%), Gaps = 37/438 (8%)
Query: 92 NDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEI 151
+DL + ++ LK E ++ TS+V ++ SL E +N + EEV I
Sbjct: 935 DDLVSQLRQTEEQVNDLK-ERLKTSTSNVEQYQAMVTSLEESLNKEK---QVTEEVRKNI 990
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKY-LESVKSEYNTANEKLFEQLNN 210
+++ K++ +T L+K + + E + EL++ + +ES++ + + +K + N
Sbjct: 991 EVR----LKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSEL-KKTLSSVQN 1045
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE 270
V Q +Q L E Q A++E ++ +E
Sbjct: 1046 EV--QEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQA--AKE 1101
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD-LSKKVNKTERELEEKQ 329
++S++ + +Q ++ +K E + +E+ +L D +SK V + E +LE++
Sbjct: 1102 QVSKMA----SVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCE-DLEKQN 1156
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL-------DDESENTY 382
L +E+L+D S K E + ++ S+ S + E+ + +E +
Sbjct: 1157 RLLHDQIEKLSDKVVASVK--EGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRF 1214
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNA-----QLLWEAKKQIADL---TEQNIILKE 434
E + + + L ++ E Q + NA Q+ + Q +L TE ++ E
Sbjct: 1215 EVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVME 1274
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
L E + L ++Q ++ ++ L++ E + ++ V
Sbjct: 1275 TNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKR 1334
Query: 495 WKSQFEDLDDVMKQQQKE 512
WK++ + L K E
Sbjct: 1335 WKARNQHLVSQQKDPDTE 1352
Score = 35.5 bits (78), Expect = 0.46
Identities = 65/359 (18%), Positives = 154/359 (42%), Gaps = 34/359 (9%)
Query: 125 EIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNIS-IKTLLDKLITKNETDINEL 183
E ++ L E + L + + L+ K+ + +DN+ + + L +N+
Sbjct: 695 EQLEKLQEQVTDLRSQNTKIS-TQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATT 753
Query: 184 RNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXX 243
+ + + ++ + ANEKL V +N +++E ++LK+ L Q
Sbjct: 754 QKQEQIINTMTQDLRGANEKLAVA---EVRAEN-LKKEKEMLKLSEVRLSQQRESLLAEQ 809
Query: 244 XXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
++ + NL+ ++ +L E +E K++ +I+ L ++ +++
Sbjct: 810 R-------GQNLLLTNLQTIQGIL-ERSETETKQR---LSSQIEKLEHEISHLKKKLENE 858
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+++++ L +L ++ T+R+L+ + + E L + + L +++ N Q+AS
Sbjct: 859 VEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQ 918
Query: 364 F-------KISNQLSC-ELDDESENTYERISLTLDKI---TNHITYLNTQIN--ETQKND 410
+ SN+ +L + T E+++ +++ T+++ + E N
Sbjct: 919 SSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNK 978
Query: 411 NAQLLWEAKKQI----ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
Q+ E +K I + E L+++L ++E E +EL + + S E+ LK
Sbjct: 979 EKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELK 1037
Score = 31.9 bits (69), Expect = 5.6
Identities = 64/363 (17%), Positives = 148/363 (40%), Gaps = 24/363 (6%)
Query: 40 LQQNVGVGDKTVAEL--KNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKL 97
LQ NV + + L +N ++ + ++ EKL +AE + +LKK
Sbjct: 728 LQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKE 787
Query: 98 YED-SASELE-ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKK 155
E SE+ + +RE++ ++ + ++ ++ E+ + ++ +I+ +
Sbjct: 788 KEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSET--ETKQRLSSQIEKLE 845
Query: 156 NSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE-QLNNAVDK 214
+ I+ ++ +++ T +L ++ + L++ + + E L Q A K
Sbjct: 846 HEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLK 905
Query: 215 QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE-MKTML--VEEK 271
Q+ EV + +Q + ++ + +L+E +KT VE+
Sbjct: 906 QHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQY 965
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
+ + +E+ +E + E R+ ++E + L KK+ + E+E +E Q+
Sbjct: 966 QAMVTSLEESLNKEKQVTEEV----RKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDD 1021
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQI--ASDFKISNQLSCELD--------DESENT 381
+E + + K + ++ N+V + + +SN+ D E++N
Sbjct: 1022 KRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNK 1081
Query: 382 YER 384
YER
Sbjct: 1082 YER 1084
>AL136382-1|CAI23513.1| 620|Homo sapiens novel protein protein.
Length = 620
Score = 54.4 bits (125), Expect = 9e-07
Identities = 73/353 (20%), Positives = 150/353 (42%), Gaps = 31/353 (8%)
Query: 111 ENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLD 170
E I +++ + I E++ + F+S++ +ALE L+K + ++ ++L
Sbjct: 76 EKINFENANLSALNLKISEQKEILIKELDTFKSVK-LALEHLLRKRDYKQTGDNLSSMLL 134
Query: 171 KLITKNETDINELRNSIKYLES--------VKSE-YNTANEKLFEQLNNAVDKQNCIQEE 221
+ +T NE++ L+ + E+ +SE NT F Q V ++ +Q +
Sbjct: 135 ENLTDNESENTNLKKKVFEKEAHIQELSCLFQSEKANTLKANRFSQSVKVVHER--LQIQ 192
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE---MKTMLVEEKLSEIKEK 278
+ + EN L + ++E KT+ +++ K++
Sbjct: 193 IHKREAENDKLKEYVKSLETKIAKWNLQSRMNKNEAIVMKEASRQKTVALKKASKVYKQR 252
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK-KVNKTERE--LEEKQEQLTHL 335
++F I+ L ++ + +ET+ N S K + KTE E +E ++Q+ +L
Sbjct: 253 LDHFTGAIEKLTSQIRDQEAKLSETISASNAWKSHYEKIVIEKTELEVQIETMKKQIINL 312
Query: 336 MEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNH 395
+E L E++ E + KV I + + N ENT ++ TL + +
Sbjct: 313 LEDLKKMEDHGKNSCEEILRKVHSIEYENETLN---------LENT--KLKTTLAALKDE 361
Query: 396 ITYLNTQINETQKNDNAQ--LLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
+ + +++E Q+ + Q L+ K Q+ L E I+K R L +N ++
Sbjct: 362 VVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLHKNNQI 414
Score = 34.7 bits (76), Expect = 0.80
Identities = 51/278 (18%), Positives = 113/278 (40%), Gaps = 17/278 (6%)
Query: 105 LEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNIS 164
L ALK E + + +++ + E+ +I + L+E A + + ++ N
Sbjct: 355 LAALKDEVVSVE-NELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLHKNNQ 413
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE-QLNNAVDKQNCIQEEVD 223
I +K + K ++ + +K LE V A +L E Q + K C +E
Sbjct: 414 ITKTKNKNVEKMR---GQMESHLKELERVCDSLTAAERRLHECQESLQCCKGKCADQEHT 470
Query: 224 LLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN--LEEMKTMLVEEKLSEIKEKDEN 281
+ +++ Q L Q + L ++K +++KL ++ +++
Sbjct: 471 IRELQGQILKQWEEYSVLAWVDGNHNLLTKLSLEEENCLIQLKCENLQQKLEQMDAENKE 530
Query: 282 FKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLND 341
++++ E L +F E E L L E LEE ++++ +E+++
Sbjct: 531 LEKKLANQEECLKHSNLKFKEKSAEYTALARQL-------EAALEEGRQKVAEEIEKMSS 583
Query: 342 TENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE 379
E+ L + + +++ + NQL C+++ + E
Sbjct: 584 RES---ALQIKILDLETELRKKNEEQNQLVCKMNSDPE 618
>AL133553-3|CAI17859.1| 2363|Homo sapiens translocated promoter
region (to activated MET oncogene) protein.
Length = 2363
Score = 54.4 bits (125), Expect = 9e-07
Identities = 79/448 (17%), Positives = 183/448 (40%), Gaps = 30/448 (6%)
Query: 80 LTEKLTIAETKHNDLK-KLYEDSASELEA------LKRENIQMHTSDVMVVPEIIDSLTE 132
L EKL + T +L+ KL E AS++ L++E +H+ + + E+ E
Sbjct: 148 LNEKLKESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDE 207
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES 192
++ + E+ ++ KK +++ ++ ++ L T NE + + + L+
Sbjct: 208 LLALGREKGNEILELKCNLENKKEEVSR----LEEQMNGLKTSNEHLQKHVEDLLTKLKE 263
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
K + + EK +LN + N + D + ++ L + A
Sbjct: 264 AKEQQASMEEKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELHKLLKEAGEANKA 323
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
+ +E+ K + +E L EK ++E++ N+ L +R+ +E+ +S
Sbjct: 324 IQDHLLEVEQSKDQMEKEML----EKIGRLEKELENANDLLSATKRKGAILSEEELAAMS 379
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK-VSQIASDFKISNQLS 371
+ V K + + +LT L +T++ L+E + NK +++ + +
Sbjct: 380 PTAAAVAK----IVKPGMKLTELYNAYVETQDQ--LLLEKLENKRINKYLDEIVKEVEAK 433
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
+ YER + ++ + +I Q++ + +A KQ + L N
Sbjct: 434 APILKRQREEYERAQKAVASLSVKLEQAMKEIQRLQEDTD-----KANKQSSVLERDNRR 488
Query: 432 LKERLSQLETENKELLIEIQTVRGSN--EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
++ ++ L + + LL+E++ RG++ + ++ D S+ N IE+++
Sbjct: 489 MEIQVKDLSQQIRVLLMELEEARGNHVIRDEEVSSADISSSSEVISQHLVSYRN-IEELQ 547
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+ +L + +++++E K
Sbjct: 548 QQNQRLLVALRELGETREREEQETTSSK 575
Score = 46.8 bits (106), Expect = 2e-04
Identities = 101/528 (19%), Positives = 219/528 (41%), Gaps = 55/528 (10%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
FK+ E+ Y EI + S Q+ + V + + E+ + QL
Sbjct: 46 FKVESEQQYFEIEKRLSHSQERL-VNETRECQSLRLELEKLNNQLKALTEK--------N 96
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++L IA+ ++ ++ + + ELEA KR+ I+ + + + ++ LTE + L
Sbjct: 97 KELEIAQDRNIAIQSQFTRTKEELEAEKRDLIRTNER----LSQELEYLTEDVKRLNEKL 152
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE------TDIN-ELRNSIKYLESVK 194
+ E+ LK + + ++S+K +L + E T +N EL+ L ++
Sbjct: 153 KESNTTKGELQLKLDELQASDVSVKYREKRLEQEKELLHSQNTWLNTELKTKTDELLALG 212
Query: 195 SEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA-R 253
E +L L N ++ + ++E+++ LK N++L + +
Sbjct: 213 REKGNEILELKCNLENKKEEVSRLEEQMNGLKTSNEHLQKHVEDLLTKLKEAKEQQASME 272
Query: 254 DKFIANLE-EMK-TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+KF L +K + L + + + K + ++ L+ KL+ + E N+ +Q+ L
Sbjct: 273 EKFHNELNAHIKLSNLYKSAADDSEAKSNELTRAVEELH-KLLKEAGEANKAIQDH---L 328
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLND----TENNSYKLIENMFNKVSQIAS----- 362
++ + ++ E+E+ EK +L +E ND T+ L E +S A+
Sbjct: 329 LEVEQSKDQMEKEMLEKIGRLEKELENANDLLSATKRKGAILSEEELAAMSPTAAAVAKI 388
Query: 363 ---DFKISNQLSCELDDESENTYE-----RISLTLDKITNHI----TYLNTQINETQKND 410
K++ + ++ + + E RI+ LD+I + L Q E ++
Sbjct: 389 VKPGMKLTELYNAYVETQDQLLLEKLENKRINKYLDEIVKEVEAKAPILKRQREEYERAQ 448
Query: 411 NAQL-----LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
A L +A K+I L E ++ S LE +N+ + I+++ + + + L+
Sbjct: 449 KAVASLSVKLEQAMKEIQRLQEDTDKANKQSSVLERDNRRMEIQVKDLSQQIRVLLMELE 508
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
++ S +I + + + +++++ +Q Q+ L
Sbjct: 509 EA--RGNHVIRDEEVSSADISSSSEVISQHLVSYRNIEELQQQNQRLL 554
Score = 46.4 bits (105), Expect = 2e-04
Identities = 82/424 (19%), Positives = 171/424 (40%), Gaps = 29/424 (6%)
Query: 32 EIGQLKS-GLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXL--TEKLTIAE 88
E+ Q++S +Q V + ++ + EL+ D +N+ ++ + TE + +
Sbjct: 1215 EVAQVESLRYRQRVELLERELQELQ-DSLNAEREKVQVTAKTMAQHEELMKKTETMNVVM 1273
Query: 89 TKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVA 148
+ L++ E +L+ ++ + ++ D++ + E L+E L + LEE
Sbjct: 1274 ETNKMLREEKERLEQDLQQMQAK-VRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDV 1332
Query: 149 LEIDLKKNSITKDNISIKTL-LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
+ + T KL+++ E ++ + + +K+E +N L
Sbjct: 1333 KRWKARNQHLVSQQKDPDTEEYRKLLSEKEVHTKRIQQLTEEIGRLKAEIARSNASL--- 1389
Query: 208 LNNAVDKQNCIQE-EVDLLKIENQN-LLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKT 265
NN QN IQ + DL K+ + +Q + K I KT
Sbjct: 1390 TNN----QNLIQSLKEDLNKVRTEKETIQKDLDAKIIDIQEKVKTITQVKKIGR--RYKT 1443
Query: 266 MLVEEKLSEIKEKDENFKQEIDMLNEKL-ICDRREFNETMQEKNILLSDLSKKVNKTERE 324
E K + K + + + D + + + + +E ET+ + L +V ++
Sbjct: 1444 QYEELKAQQDKVMETSAQSSGDHQEQHVSVQEMQELKETLNQAETKSKSLESQVENLQKT 1503
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYER 384
L EK+ + +L EQ ++ +L +++ ++ +Q QL ++ ++ E T +
Sbjct: 1504 LSEKETEARNLQEQTVQLQSELSRLRQDLQDRTTQ-------EEQLRQQITEKEEKTRKA 1556
Query: 385 ISLTLDKITNHITYLNTQI---NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
I KI H+ + Q+ NE K N L + + +T + R+S+LE
Sbjct: 1557 IVAAKSKIA-HLAGVKDQLTKENEELKQRNGALDQQKDELDVRITALKSQYEGRISRLER 1615
Query: 442 ENKE 445
E +E
Sbjct: 1616 ELRE 1619
Score = 46.0 bits (104), Expect = 3e-04
Identities = 61/331 (18%), Positives = 131/331 (39%), Gaps = 14/331 (4%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E ++ EL++S+ E K + E+L + N + E +L+ E + L Q
Sbjct: 1232 ERELQELQDSLN-AEREKVQVTAKTMAQHEELMKKTETMNVVMETNKMLREEKERLEQDL 1290
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTML-VEEKLSEIKEKDENFKQEIDMLNEKLIC 295
+ A L E ML E+KL E K + + +++++
Sbjct: 1291 QQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKRWKARNQ-HLVSQQKDP 1349
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
D E+ + + EK + +K++ + E+ + ++ L + +N L E++ N
Sbjct: 1350 DTEEYRKLLSEKEVH----TKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDL-N 1404
Query: 356 KVSQIASDFKISNQLSCELDD--ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQ 413
KV I L ++ D E T ++ + L Q ++ + +AQ
Sbjct: 1405 KVR--TEKETIQKDLDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMET-SAQ 1461
Query: 414 LLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
+ ++Q + E LKE L+Q ET++K L +++ ++ + E ++
Sbjct: 1462 SSGDHQEQHVSVQEMQE-LKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQ 1520
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDD 504
+++D T+ + + Q + ++
Sbjct: 1521 LQSELSRLRQDLQDRTTQEEQLRQQITEKEE 1551
Score = 36.7 bits (81), Expect = 0.20
Identities = 55/305 (18%), Positives = 125/305 (40%), Gaps = 32/305 (10%)
Query: 53 ELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKREN 112
E+ I + ++ LT + ++ DL K+ +E E ++++
Sbjct: 1362 EVHTKRIQQLTEEIGRLKAEIARSNASLTNNQNLIQSLKEDLNKV----RTEKETIQKD- 1416
Query: 113 IQMHTSDVMVVPEIIDSLTEVINTLTNGFESL---EEVALEIDLKKNSITKD-NISIKTL 168
+ D+ + I + ++ +E L ++ +E + + ++ ++S++ +
Sbjct: 1417 LDAKIIDIQEKVKTITQVKKIGRRYKTQYEELKAQQDKVMETSAQSSGDHQEQHVSVQEM 1476
Query: 169 --LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLK 226
L + + + ET L + ++ L+ SE T L EQ + + +++++
Sbjct: 1477 QELKETLNQAETKSKSLESQVENLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQDRT 1536
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEI 286
+ + L Q ++ IA+L +K L +E E+K+++ Q+
Sbjct: 1537 TQEEQLRQQITEKEEKTRKAIVAAKSK---IAHLAGVKDQLTKEN-EELKQRNGALDQQK 1592
Query: 287 DMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNS 346
D L+ ++ L S ++++ EREL E QE+ HL EQ ++ + S
Sbjct: 1593 DELDVRITA--------------LKSQYEGRISRLERELREHQER--HL-EQRDEPQEPS 1635
Query: 347 YKLIE 351
K+ E
Sbjct: 1636 NKVPE 1640
Score = 35.9 bits (79), Expect = 0.34
Identities = 84/438 (19%), Positives = 177/438 (40%), Gaps = 37/438 (8%)
Query: 92 NDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEI 151
+DL + ++ LK E ++ TS+V ++ SL E +N + EEV I
Sbjct: 935 DDLVSQLRQTEEQVNDLK-ERLKTSTSNVEQYQAMVTSLEESLNKEK---QVTEEVRKNI 990
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKY-LESVKSEYNTANEKLFEQLNN 210
+++ K++ +T L+K + + E + EL++ + +ES++ + + +K + N
Sbjct: 991 EVR----LKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSEL-KKTLSSVQN 1045
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE 270
V Q +Q L E Q A++E ++ +E
Sbjct: 1046 EV--QEALQRASTALSNEQQARRDCQEQAKIAVEAQNKYERELMLHAADVEALQA--AKE 1101
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD-LSKKVNKTERELEEKQ 329
++S++ + +Q ++ +K E + +E+ +L D +SK V + E +LE++
Sbjct: 1102 QVSKMA----SVRQHLEETTQKAESQLLECKASWEERERMLKDEVSKCVCRCE-DLEKQN 1156
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL-------DDESENTY 382
L +E+L+D S K E + ++ S+ S + E+ + +E +
Sbjct: 1157 RLLHDQIEKLSDKVVASVK--EGVQGPLNVSLSEEGKSQEQILEILRFIRREKEIAETRF 1214
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNA-----QLLWEAKKQIADL---TEQNIILKE 434
E + + + L ++ E Q + NA Q+ + Q +L TE ++ E
Sbjct: 1215 EVAQVESLRYRQRVELLERELQELQDSLNAEREKVQVTAKTMAQHEELMKKTETMNVVME 1274
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
L E + L ++Q ++ ++ L++ E + ++ V
Sbjct: 1275 TNKMLREEKERLEQDLQQMQAKVRKLELDILPLQEANAELSEKSGMLQAEKKLLEEDVKR 1334
Query: 495 WKSQFEDLDDVMKQQQKE 512
WK++ + L K E
Sbjct: 1335 WKARNQHLVSQQKDPDTE 1352
Score = 35.5 bits (78), Expect = 0.46
Identities = 65/359 (18%), Positives = 154/359 (42%), Gaps = 34/359 (9%)
Query: 125 EIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNIS-IKTLLDKLITKNETDINEL 183
E ++ L E + L + + L+ K+ + +DN+ + + L +N+
Sbjct: 695 EQLEKLQEQVTDLRSQNTKIS-TQLDFASKRYEMLQDNVEGYRREITSLHERNQKLTATT 753
Query: 184 RNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXX 243
+ + + ++ + ANEKL V +N +++E ++LK+ L Q
Sbjct: 754 QKQEQIINTMTQDLRGANEKLAVA---EVRAEN-LKKEKEMLKLSEVRLSQQRESLLAEQ 809
Query: 244 XXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
++ + NL+ ++ +L E +E K++ +I+ L ++ +++
Sbjct: 810 R-------GQNLLLTNLQTIQGIL-ERSETETKQR---LSSQIEKLEHEISHLKKKLENE 858
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+++++ L +L ++ T+R+L+ + + E L + + L +++ N Q+AS
Sbjct: 859 VEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLKQHLSNMEVQVASQ 918
Query: 364 F-------KISNQLSC-ELDDESENTYERISLTLDKI---TNHITYLNTQIN--ETQKND 410
+ SN+ +L + T E+++ +++ T+++ + E N
Sbjct: 919 SSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNK 978
Query: 411 NAQLLWEAKKQI----ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
Q+ E +K I + E L+++L ++E E +EL + + S E+ LK
Sbjct: 979 EKQVTEEVRKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSELK 1037
Score = 31.9 bits (69), Expect = 5.6
Identities = 64/363 (17%), Positives = 148/363 (40%), Gaps = 24/363 (6%)
Query: 40 LQQNVGVGDKTVAEL--KNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKL 97
LQ NV + + L +N ++ + ++ EKL +AE + +LKK
Sbjct: 728 LQDNVEGYRREITSLHERNQKLTATTQKQEQIINTMTQDLRGANEKLAVAEVRAENLKKE 787
Query: 98 YED-SASELE-ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKK 155
E SE+ + +RE++ ++ + ++ ++ E+ + ++ +I+ +
Sbjct: 788 KEMLKLSEVRLSQQRESLLAEQRGQNLLLTNLQTIQGILERSET--ETKQRLSSQIEKLE 845
Query: 156 NSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE-QLNNAVDK 214
+ I+ ++ +++ T +L ++ + L++ + + E L Q A K
Sbjct: 846 HEISHLKKKLENEVEQRHTLTRNLDVQLLDTKRQLDTETNLHLNTKELLKNAQKEIATLK 905
Query: 215 QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE-MKTML--VEEK 271
Q+ EV + +Q + ++ + +L+E +KT VE+
Sbjct: 906 QHLSNMEVQVASQSSQRTGKGQPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQY 965
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
+ + +E+ +E + E R+ ++E + L KK+ + E+E +E Q+
Sbjct: 966 QAMVTSLEESLNKEKQVTEEV----RKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDD 1021
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQI--ASDFKISNQLSCELD--------DESENT 381
+E + + K + ++ N+V + + +SN+ D E++N
Sbjct: 1022 KRRAIESMEQQLSELKKTLSSVQNEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNK 1081
Query: 382 YER 384
YER
Sbjct: 1082 YER 1084
>AC012487-1|AAX88838.1| 1583|Homo sapiens unknown protein.
Length = 1583
Score = 54.4 bits (125), Expect = 9e-07
Identities = 78/388 (20%), Positives = 162/388 (41%), Gaps = 35/388 (9%)
Query: 120 VMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETD 179
V V+ + +SL ++ N +E LE++ + + ++++ L L+ E +
Sbjct: 679 VNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQE 738
Query: 180 INELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXX 239
LR K LE ++SE L E + NA +K ++ENQNLL
Sbjct: 739 KVLLR---KELEEIQSEKEALQSDLLE-MKNANEKT----------RLENQNLLIQVEEV 784
Query: 240 XXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRRE 299
FI E +K +L E+K E++++ + E+ +L + L
Sbjct: 785 SQTCSKSEIHNEKEKCFIKEHENLKPLL-EQK--ELRDR----RAELILLKDSLAKSPSV 837
Query: 300 FNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL---MEQLNDTENNSYKLIENMFNK 356
N+ + + +L +K+ E+E +EK+E++ + + ++S K + + +
Sbjct: 838 KNDPLSS----VKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEE 893
Query: 357 VSQIASDFKISNQLSCELDD--ESENTYERISLTLDKITNHITYLNTQIN--ETQKNDNA 412
+ + S+ +QLS + D + +Y+ + L +K + + + N E + D
Sbjct: 894 LESLRSE---KDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLT 950
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
+ L + Q + N L R+ L++ K L ++I V+ + V L+
Sbjct: 951 RQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKE 1010
Query: 473 XXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
NE+E+++ ++ + K Q +
Sbjct: 1011 QKIKEHATTVNELEELQVQLQKQKKQLQ 1038
Score = 50.8 bits (116), Expect = 1e-05
Identities = 87/381 (22%), Positives = 172/381 (45%), Gaps = 40/381 (10%)
Query: 99 EDSASELEALKRENIQMHTSDVMVVPE--IIDSLTEVINTLTNGFESLEEVALEIDLKKN 156
E E+++LK + H ++ + E + DS E + TL + L+E + +K
Sbjct: 319 EQHNREVQSLKEQ----HQKEISELNETFLSDSEKEKL-TLMFEIQGLKEQCENLQQEKQ 373
Query: 157 SITKDNISIKTLLDKLITKNETDINELRNSIKY-LESVKSEYNTANEKLFEQLNNAVDKQ 215
+ S++ +++ L +T++ E I ES+K + + +L ++L A ++
Sbjct: 374 EAILNYESLREIMEIL----QTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEK 429
Query: 216 NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML--VEEKLS 273
+ + E V+ L+ EN+ LL ++ +L + TML +E K++
Sbjct: 430 DALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKIN 489
Query: 274 EI-KEKDE-------------NFKQEIDMLNEKLICD-RREFNETMQEKNILLSDLSKKV 318
+ +EKD+ NF ++ + E+LI + ++ +T+Q S+L +KV
Sbjct: 490 SLTEEKDDFINKLKNSHEEMDNFHKKCER-EERLILELGKKVEQTIQYN----SELEQKV 544
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
N+ LEE ++ ++L L E+ +++ S ++ +N+LS E S
Sbjct: 545 NELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLS 604
Query: 379 ENTYERISLTLDKI-TNHITYLNTQIN---ETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ +S D I HIT L ++ E Q N N L E +++ T+ LKE
Sbjct: 605 RDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKE 664
Query: 435 RLSQL--ETENKELLIEIQTV 453
S++ ++E K+++ +Q V
Sbjct: 665 MGSEVSEDSEEKDVVNVLQAV 685
Score = 50.0 bits (114), Expect = 2e-05
Identities = 79/379 (20%), Positives = 149/379 (39%), Gaps = 21/379 (5%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDL 153
LK ++++ EL + + H +++ + E+ ++L + + E LE
Sbjct: 143 LKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLR 202
Query: 154 KKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ---LNN 210
K S + I ++L + T E +NE +K+LE E + + L ++ +NN
Sbjct: 203 KATSNANQDNQICSILLQENTFVEQVVNE---KVKHLEDTLKELESQHSILKDEVTYMNN 259
Query: 211 AVDKQNCIQEEV-DLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
K + + D E ++L +A L + VE
Sbjct: 260 LKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVE 319
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
+ E++ E ++EI LNE + D + T+ + L + + + + ++E
Sbjct: 320 QHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNY 379
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKV-SQIASDFKISNQLSCELDDESENTYERISLT 388
E L +ME L S I F + Q ASD EL + +
Sbjct: 380 ESLREIMEILQTELGESAGKISQEFESMKQQQASDVH-------ELQQKLRTAFTEKDAL 432
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLI 448
L+ + N + N ++ Q +L+ E + I +L E+N + LSQ +T KEL
Sbjct: 433 LETV-NRLQGENEKLLSQQ-----ELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEG 486
Query: 449 EIQTVRGSNEEVTLNLKDS 467
+I ++ ++ LK+S
Sbjct: 487 KINSLTEEKDDFINKLKNS 505
Score = 48.4 bits (110), Expect = 6e-05
Identities = 70/380 (18%), Positives = 158/380 (41%), Gaps = 27/380 (7%)
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E K N +K + + EL++ ++E Q ++ + D L+ + L G ES + +
Sbjct: 863 EEKINKIKLVAVKAKKELDSSRKET-QTVKEELESLRSEKDQLSASMRDLIQGAESYKNL 921
Query: 148 ALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
LE + + + + K + + E +LRNS E++ S+ NE L +
Sbjct: 922 LLEYEKQSEQLDVE----KERANNFEHRIEDLTRQLRNSTLQCETINSD----NEDLLAR 973
Query: 208 LNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML 267
+ + N EV +L+++ + + LEE++ L
Sbjct: 974 IETL--QSNAKLLEVQILEVQRAKAM-VDKELEAEKLQKEQKIKEHATTVNELEELQVQL 1030
Query: 268 VEEK--LSEIKEKDENFK---QEIDMLNEKLICDRR---EFNETMQEKNILLSDLSKKVN 319
++K L + ++ E K Q+ ++N ++ R E N+ + KN + DL +++
Sbjct: 1031 QKQKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIK 1090
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ---LSCELDD 376
+++ E QE++T L + E + K+ + + ++A + L L
Sbjct: 1091 IQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKG 1150
Query: 377 ESENTYERI---SLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
E E + +++ + L +IT+ ++ + +T + + L ++++ L E+ K
Sbjct: 1151 ELEASQQQVEVYKIQLAEITSEKHKIHEHL-KTSAEQHQRTLSAYQQRVTALQEECRAAK 1209
Query: 434 ERLSQLETENKELLIEIQTV 453
+ + +E + + + V
Sbjct: 1210 AEQATVTSEFESYKVRVHNV 1229
Score = 44.4 bits (100), Expect = 0.001
Identities = 89/419 (21%), Positives = 170/419 (40%), Gaps = 29/419 (6%)
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTL--TNGFESLE 145
E K N+L E++ E + + ++ + V+ E + L+ + +L N S E
Sbjct: 541 EQKVNELTGGLEETLKEKDQ-NDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSE 599
Query: 146 EVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLF 205
+ L DL+ K+++ +K + +L K + + E N K LE+ + + +L+
Sbjct: 600 KKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLY 659
Query: 206 EQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX-XXXXARDKFIANLEEMK 264
L + + EE D++ N+LQ RD+ + LE+
Sbjct: 660 GFLKEMGSEVSEDSEEKDVV-----NVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEI 714
Query: 265 TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L EE + + +E + D EK++ R+E E EK L SDL + N E+
Sbjct: 715 KCLQEESVVQCEELKSLLR---DYEQEKVLL-RKELEEIQSEKEALQSDLLEMKNANEKT 770
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYER 384
E Q L +E+++ T + S I N K F ++ L ++ E R
Sbjct: 771 RLENQNLLIQ-VEEVSQTCSKSE--IHNEKEKC------FIKEHENLKPLLEQKELRDRR 821
Query: 385 ISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENK 444
L L K + + + KND + E +++I +L ++ +E++++++
Sbjct: 822 AELILLKD-------SLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAV 874
Query: 445 ELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLD 503
+ E+ + R + V L+ + E K ++E++ Q E LD
Sbjct: 875 KAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLD 933
Score = 39.9 bits (89), Expect = 0.021
Identities = 97/473 (20%), Positives = 191/473 (40%), Gaps = 46/473 (9%)
Query: 13 ENIRNIIHAFKIRLEECYKEIGQLKSGLQQ----NVGVGD------KTVAELKNDEINSM 62
E++ I K + E +EI L+S +QQ N + K +A+ K E + +
Sbjct: 1083 EDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHL 1142
Query: 63 IRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMV 122
I Q K+ +AE ++ K++E + E +R + + V
Sbjct: 1143 ILQASLKGELEASQQQVEVYKIQLAEIT-SEKHKIHEHLKTSAEQHQR-TLSAYQQRVTA 1200
Query: 123 VPEIIDSLTEVINTLTNGFESLE-EVALEIDLKKNS---------ITKDNISIKTLLDKL 172
+ E + T+T+ FES + V + +KN ++ ++ L+D+L
Sbjct: 1201 LQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQL 1260
Query: 173 ITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL 232
K + N L+ ++ L++++SE++T E+ + L V K+ ++E+ L I+++N+
Sbjct: 1261 KIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREK--LCSIQSENM 1318
Query: 233 LQXXXXXXXXXXXXXXXXXARDKF---IANLEEMKTMLVEEKLSEI-KEKDENFKQEIDM 288
+ R+ F + +L+E VE ++ K + + F+ + +
Sbjct: 1319 MMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQLKNEP 1378
Query: 289 LNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
+ ++ + +N L L ++ RE E E T E ++ +
Sbjct: 1379 TTRSPVSSQQSLKNLRERRNTDLPLLD--MHTVTREEGEGME--TTDTESVSSASTYTQS 1434
Query: 349 LIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQK 408
L E + N + + K+ L +E T E + L T +LN + ET+
Sbjct: 1435 L-EQLLN-----SPETKLEPPLW-----HAEFTKEELVQKLSSTTKSADHLNGLLRETEA 1483
Query: 409 NDNAQLLWEAKKQIADL--TEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
NA L+ + K +++ E+N ++ + LE LL I GS E
Sbjct: 1484 T-NAILMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKPGSERE 1535
Score = 38.7 bits (86), Expect = 0.049
Identities = 70/390 (17%), Positives = 143/390 (36%), Gaps = 14/390 (3%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++ T+ + D ++L ++ +L K I+ ++ + + ++L E I +L +
Sbjct: 1052 QQTTLMNMEIADYERLMKELNQKLTN-KNNKIEDLEQEIKIQKQKQETLQEEITSLQSSV 1110
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTL-LDKLITKNETDINELRNSIKYLESVK---SEY 197
+ EE +I K+ K D LI + EL S + +E K +E
Sbjct: 1111 QQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLK-GELEASQQQVEVYKIQLAEI 1169
Query: 198 NTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFI 257
+ K+ E L + ++ Q + R +
Sbjct: 1170 TSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNV 1229
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
++ K+M E K++ E+ + ID L KL + + E L S+
Sbjct: 1230 LKQQKNKSMSQAET-EGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTL 1288
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQLSCE--- 373
+ + + L+E + L E+L ++ + + VSQ+ S ++ N +
Sbjct: 1289 LERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRH 1348
Query: 374 LDDESENTYERISLTLDKITNHITYLN---TQINETQKNDNAQLLWEAKKQIADLTEQNI 430
L +E T E + L K+ + L T + + + L E + L + +
Sbjct: 1349 LQEEHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHT 1408
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEV 460
+ +E +ET + E + T S E++
Sbjct: 1409 VTREEGEGMETTDTESVSSASTYTQSLEQL 1438
Score = 35.1 bits (77), Expect = 0.60
Identities = 50/200 (25%), Positives = 96/200 (48%), Gaps = 19/200 (9%)
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM-QEKNILLSD---LSKKVNKTER 323
V++ EI++ F+++I L ++L E ET+ Q +NI+ ++ K +N +
Sbjct: 79 VKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQE 138
Query: 324 ELEE----KQEQLTHLMEQL----NDTENNSYKLIENMFNKVSQI-ASDFKISNQLSCEL 374
EL + QE++ LM Q+ + E KL E N V Q AS+ I + CEL
Sbjct: 139 ELLQLKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECEL 198
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
++ + T + ++I + + NT + E N+ + L + K +L Q+ ILK+
Sbjct: 199 ENLRKATSN--ANQDNQICSILLQENTFV-EQVVNEKVKHLEDTLK---ELESQHSILKD 252
Query: 435 RLSQLETENKELLIEIQTVR 454
++ + +L ++ Q ++
Sbjct: 253 EVTYMNNLKLKLEMDAQHIK 272
Score = 31.1 bits (67), Expect = 9.8
Identities = 31/139 (22%), Positives = 63/139 (45%), Gaps = 14/139 (10%)
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENT 381
++E+E+ ++ ++L + N K IEN+ N++ + S + + +E+ NT
Sbjct: 2 KQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNT 61
Query: 382 YERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI-ADLTEQNIILKERLSQLE 440
+S L K N+ DN + L E ++I EQ + L+++L
Sbjct: 62 QLELSEQL-KFQNN------------SEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATT 108
Query: 441 TENKELLIEIQTVRGSNEE 459
E KE + ++Q + +N +
Sbjct: 109 DEKKETVTQLQNIIEANSQ 127
>AB209115-1|BAD92352.1| 1065|Homo sapiens restin isoform a variant
protein.
Length = 1065
Score = 54.4 bits (125), Expect = 9e-07
Identities = 82/441 (18%), Positives = 184/441 (41%), Gaps = 29/441 (6%)
Query: 82 EKLTIAETK-HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNG 140
E+L A+ K ND+ ++ + S L + N ++ + V E+ LT+ +
Sbjct: 542 EQLIKAKEKLENDIAEIMKMSGDNSSQLTKMNDELRLKE-RDVEELQLKLTKANENASFL 600
Query: 141 FESLEEVALEIDLKKNSITKDNISIKTLLDKLIT----KNETDINELRNSIKYLESVKSE 196
+S+E++ ++ + + K + K L++ ++ K ET N+ + E SE
Sbjct: 601 QKSIEDMTVKAEQSQQEAAKKHEEEKKELERKLSDLEKKMETSHNQCQELKARYERATSE 660
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
T +E++ + L + ++++ + EN LLQ A D
Sbjct: 661 TKTKHEEILQNLQKTLLDT---EDKLKGAREENSGLLQELEELRKQAEKAKAAQTAEDA- 716
Query: 257 IANLEEMKTMLVEE--KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
+ +E+M E L + K+ + + E+D L E + + E N++ + LL+
Sbjct: 717 MQIMEQMTKEKTETLASLEDTKQTNAKLQNELDTLKENNLKNVEELNKSKE----LLTVE 772
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++K+ + +E+E ++ +QL+ + + KL E + ++ S K+ + S L
Sbjct: 773 NQKMEEFRKEIETLKQAAAQKSQQLSALQEENVKLAEELGRSRDEVTSHQKLEEERSV-L 831
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQIADLTEQNIIL 432
+++ +R S + L I+ T + L + + ++ L +N
Sbjct: 832 NNQLLEMKKRESKFIKDADEEKASLQKSISITSALLTEKDAELEKLRNEVTVLRGENASA 891
Query: 433 KERLSQLET-ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK 491
K S ++T E+ ++ +E++ + + L LK++ ++E E +
Sbjct: 892 KSLHSVVQTLESDKVKLELKV-----KNLELQLKENKRQLSSSSGNTDTQADEDE----R 942
Query: 492 VMEWKSQFEDLDDVMKQQQKE 512
E + + L+ V+ Q++
Sbjct: 943 AQESQQMIDFLNSVIVDLQRK 963
Score = 44.4 bits (100), Expect = 0.001
Identities = 84/476 (17%), Positives = 183/476 (38%), Gaps = 31/476 (6%)
Query: 63 IRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDS-----ASELEALKRENIQMHT 117
I+ L L KL A +++D+ L++ AS +A++ +
Sbjct: 328 IKALYTATEKLSKENESLKSKLEHANKENSDVIALWKSKLETAIASHQQAMEELKVSFSK 387
Query: 118 SDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNE 177
E + T++ + +E + + D ++ + K+ +++ L K+I + E
Sbjct: 388 GLGTETAEFAELKTQIEKMRLDYQHEIENLQNQQDSERAAHAKEMEALRAKLMKVIKEKE 447
Query: 178 TDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXX 237
+ +R+ L+ + ++ E +L A K+ E + +++ +
Sbjct: 448 NSLEAIRSK---LDKAEDQHLVEMEDTLNKLQEAEIKKEKFAEASEEAVSVQRSMQETVN 504
Query: 238 XXXXXXXXXXXXXXARDKFIANLEEMKTMLVE-----EKLSEIKEKDENFKQEIDMLNEK 292
+K NL +M+ E E+L + KEK EN EI ++
Sbjct: 505 KLHQKEEQFNMLSSDLEKLRENLADMEAKFREKDEREEQLIKAKEKLENDIAEIMKMSGD 564
Query: 293 LICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIEN 352
+ N+ ++ K + +L K+ K Q+ + + + ++ + K E
Sbjct: 565 NSSQLTKMNDELRLKERDVEELQLKLTKANENASFLQKSIEDMTVKAEQSQQEAAKKHEE 624
Query: 353 MFNKVSQIASDFKISNQLSCELDDESENTYER-ISLTLDKITNHITYLNTQINETQ---- 407
++ + SD + + S E + YER S T K + L + +T+
Sbjct: 625 EKKELERKLSDLEKKMETSHNQCQELKARYERATSETKTKHEEILQNLQKTLLDTEDKLK 684
Query: 408 --KNDNAQLLWE-------AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNE 458
+ +N+ LL E A+K A T ++ + + + Q+ E E L ++ + +N
Sbjct: 685 GAREENSGLLQELEELRKQAEKAKAAQTAEDAM--QIMEQMTKEKTETLASLEDTKQTNA 742
Query: 459 EVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKT-KVMEWKSQFEDLDDVMKQQQKEL 513
++ N D+ S E+ ++ K+ E++ + E L Q+ ++L
Sbjct: 743 KLQ-NELDTLKENNLKNVEELNKSKELLTVENQKMEEFRKEIETLKQAAAQKSQQL 797
>AB209109-1|BAD92346.1| 1096|Homo sapiens TATA element modulatory
factor 1 variant protein.
Length = 1096
Score = 54.4 bits (125), Expect = 9e-07
Identities = 91/479 (18%), Positives = 200/479 (41%), Gaps = 41/479 (8%)
Query: 48 DKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEA 107
+K + E D + + ++ T+++ AE K K + + E++
Sbjct: 474 EKALLEEAFDNLKDEMFRVKEESSSISSLKDEFTQRIAEAEKKVQLACKERDAAKKEIKN 533
Query: 108 LKRE-NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE---IDLKKNSITKDNI 163
+K E ++++S+ +++ E I L E L + L I K + K+N
Sbjct: 534 IKEELATRLNSSETA---DLLKEKDEQIRGLMEEGEKLSKQQLHNSNIIKKLRAKDKENE 590
Query: 164 SIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVD 223
++ L+K + + E ++ L+ + E V+ ++ +KL + +Q ++D
Sbjct: 591 NMVAKLNKKVKELEEELQHLKQVLDGKEEVEKQHRENIKKLNSMVERQEKDLGRLQVDMD 650
Query: 224 LLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFK 283
L+ +N+++ A+D + M +E+LS EK +
Sbjct: 651 ELEEKNRSIQAALDSAYKELTDLHKANAAKDSEAQEAALSREMKAKEELSAALEKAQE-- 708
Query: 284 QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTH----LMEQL 339
+ R+ ET+ I + DL + +TE+ K++ L H L ++L
Sbjct: 709 ------------EARQQQETLA---IQVGDLRLALQRTEQAAARKEDYLRHEIGELQQRL 753
Query: 340 NDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL-DKITNHITY 398
+ EN + +L +++ + + +I N L L ++ +++E++ L D++ T
Sbjct: 754 QEAENRNQELSQSVSSTTRPLLR--QIEN-LQATLGSQT-SSWEKLEKNLSDRLGESQTL 809
Query: 399 LNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS----QLETENKELLIEIQTVR 454
L + E ++ +LL K Q++ + QN +L++ S QLE+E K L +++
Sbjct: 810 LAAAV-ERERAATEELL-ANKIQMSSMESQNSLLRQENSRFQAQLESE-KNRLCKLEDEN 866
Query: 455 GSNEEVTLNLKDSSTXXXXXXXXXXXXSN-EIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
+ NLKD N ++E + KV + + + + +K+++++
Sbjct: 867 NRYQVELENLKDEYVRTLEETRKEKTLLNSQLEMERMKVEQERKKAIFTQETIKEKERK 925
>BC132784-1|AAI32785.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 54.0 bits (124), Expect = 1e-06
Identities = 93/439 (21%), Positives = 187/439 (42%), Gaps = 38/439 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L E+L+ E + +LKK +E+ +K+E + T E++ +L + TLTN
Sbjct: 443 LKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDT-------ELL-ALQTKLETLTN 494
Query: 140 GFESLEEVALEIDLKKNSIT-KDNIS--IKTLLDKLITKNETDINELRNSIKYLESVKSE 196
F ++ I++ K S+T K+ + ++T +D L + E L K ++ + E
Sbjct: 495 QFSDSKQ---HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEE 551
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
T ++ + L + +D + + +V++L+ + +NL + +
Sbjct: 552 KGTQAGEIHD-LKDMLDVK---ERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQAD 607
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
N + T L EE L+E + E K++ D D RE E + L DL +
Sbjct: 608 TTNTDTALTTL-EEALAEKERTIERLKEQRDR-------DEREKQEEIDNYKKDLKDLKE 659
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
KV+ + +L EK+ L L E + ++ K + K +IA + K L E
Sbjct: 660 KVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRL--KTLEIALEQKKEECLKMESQL 717
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERL 436
+ + + ++++ I +L +I T+ D + +A+ ++ L E ILKE
Sbjct: 718 KKAHEAALEARASPEMSDRIQHLEREI--TRYKDESS---KAQAEVDRLLE---ILKEVE 769
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED-MKTKVMEW 495
++ ++K++ + V+ N++V NLK + ED + +
Sbjct: 770 NEKNDKDKKIAELERQVKDQNKKVA-NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL 828
Query: 496 KSQFEDLDDVMKQQQKELK 514
+ DD +++ ++ L+
Sbjct: 829 QDSLRKKDDRIEELEEALR 847
Score = 48.8 bits (111), Expect = 5e-05
Identities = 67/379 (17%), Positives = 158/379 (41%), Gaps = 12/379 (3%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++LEE+ L I+ +K ++ + SIK LL+ L +K + + + ++E + +
Sbjct: 286 KTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHH 345
Query: 202 -EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L EQ +K+N + E + EN + ++ + +L
Sbjct: 346 LESLLEQ----KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDL 401
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDR-REFNETMQEKNILLSDLSKKV 318
EE ML +E++E KQ E+ + K + ++ + E + K +L KK
Sbjct: 402 EEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKA 461
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ E+ + +++L+ +L + + + N F+ Q K S +
Sbjct: 462 AGLQAEIGQVKQELSRKDTELLALQ-TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAIL 520
Query: 379 ENTYERISLTLDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
+ + + L L++ + QI + +K A + + K + D+ E+ + +L+++
Sbjct: 521 QTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML-DVKERKVNVLQKK 579
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
+ L+ + ++ ++ +++ + + + ++ T IE +K +
Sbjct: 580 IENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRD 639
Query: 496 KSQFEDLDDVMKQQQKELK 514
+ + ++ D K+ K+LK
Sbjct: 640 EREKQEEIDNYKKDLKDLK 658
Score = 44.0 bits (99), Expect = 0.001
Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 12/225 (5%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVK---SEYN 198
E L+EV E + K I + +K K+ + E + S + LE + N
Sbjct: 763 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLN 822
Query: 199 TANEKLFEQLNNAVDK----QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
++++L + L D+ + ++E V + L Q A +
Sbjct: 823 DSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 882
Query: 255 KFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDM-LNEKLICDRREFNETMQEK--NI 309
K LE MK L ++ L+E + N + E L E L + + EK NI
Sbjct: 883 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 942
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF 354
L +LS KT+ E+ + + L++QL N KL+ + +
Sbjct: 943 ALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNY 987
Score = 33.5 bits (73), Expect = 1.8
Identities = 50/200 (25%), Positives = 82/200 (41%), Gaps = 18/200 (9%)
Query: 48 DKTVAELKND--EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSA--- 102
DK +AEL+ + N + L + E+ E ND + +DS
Sbjct: 776 DKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKK 835
Query: 103 ----SELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
ELE RE++Q+ MV+ + + T + ++E+V E++ K +
Sbjct: 836 DDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKL 895
Query: 159 TKDNISI---KTLLDKLITKNETDINE-LRNSIKYLESVKSEYNTANEKLFEQLNNAVDK 214
+ S+ +T L L + + E L + L + SE AN L E L+++ K
Sbjct: 896 SSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISE-KDANIALLE-LSSSKKK 953
Query: 215 QNCIQEEVDLLKIENQNLLQ 234
QEEV LK E L+Q
Sbjct: 954 ---TQEEVAALKREKDRLVQ 970
>BC132782-1|AAI32783.1| 1116|Homo sapiens ELKS/RAB6-interacting/CAST
family member 1 protein.
Length = 1116
Score = 54.0 bits (124), Expect = 1e-06
Identities = 93/439 (21%), Positives = 187/439 (42%), Gaps = 38/439 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L E+L+ E + +LKK +E+ +K+E + T E++ +L + TLTN
Sbjct: 443 LKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDT-------ELL-ALQTKLETLTN 494
Query: 140 GFESLEEVALEIDLKKNSIT-KDNIS--IKTLLDKLITKNETDINELRNSIKYLESVKSE 196
F ++ I++ K S+T K+ + ++T +D L + E L K ++ + E
Sbjct: 495 QFSDSKQ---HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEE 551
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
T ++ + L + +D + + +V++L+ + +NL + +
Sbjct: 552 KGTQAGEIHD-LKDMLDVK---ERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQAD 607
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
N + T L EE L+E + E K++ D D RE E + L DL +
Sbjct: 608 TTNTDTALTTL-EEALAEKERTIERLKEQRDR-------DEREKQEEIDNYKKDLKDLKE 659
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
KV+ + +L EK+ L L E + ++ K + K +IA + K L E
Sbjct: 660 KVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRL--KTLEIALEQKKEECLKMESQL 717
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERL 436
+ + + ++++ I +L +I T+ D + +A+ ++ L E ILKE
Sbjct: 718 KKAHEAALEARASPEMSDRIQHLEREI--TRYKDESS---KAQAEVDRLLE---ILKEVE 769
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED-MKTKVMEW 495
++ ++K++ + V+ N++V NLK + ED + +
Sbjct: 770 NEKNDKDKKIAELERQVKDQNKKVA-NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL 828
Query: 496 KSQFEDLDDVMKQQQKELK 514
+ DD +++ ++ L+
Sbjct: 829 QDSLRKKDDRIEELEEALR 847
Score = 48.8 bits (111), Expect = 5e-05
Identities = 67/379 (17%), Positives = 158/379 (41%), Gaps = 12/379 (3%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++LEE+ L I+ +K ++ + SIK LL+ L +K + + + ++E + +
Sbjct: 286 KTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHH 345
Query: 202 -EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L EQ +K+N + E + EN + ++ + +L
Sbjct: 346 LESLLEQ----KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDL 401
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDR-REFNETMQEKNILLSDLSKKV 318
EE ML +E++E KQ E+ + K + ++ + E + K +L KK
Sbjct: 402 EEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKA 461
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ E+ + +++L+ +L + + + N F+ Q K S +
Sbjct: 462 AGLQAEIGQVKQELSRKDTELLALQ-TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAIL 520
Query: 379 ENTYERISLTLDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
+ + + L L++ + QI + +K A + + K + D+ E+ + +L+++
Sbjct: 521 QTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML-DVKERKVNVLQKK 579
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
+ L+ + ++ ++ +++ + + + ++ T IE +K +
Sbjct: 580 IENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRD 639
Query: 496 KSQFEDLDDVMKQQQKELK 514
+ + ++ D K+ K+LK
Sbjct: 640 EREKQEEIDNYKKDLKDLK 658
Score = 44.0 bits (99), Expect = 0.001
Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 12/225 (5%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVK---SEYN 198
E L+EV E + K I + +K K+ + E + S + LE + N
Sbjct: 763 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLN 822
Query: 199 TANEKLFEQLNNAVDK----QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
++++L + L D+ + ++E V + L Q A +
Sbjct: 823 DSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 882
Query: 255 KFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDM-LNEKLICDRREFNETMQEK--NI 309
K LE MK L ++ L+E + N + E L E L + + EK NI
Sbjct: 883 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 942
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF 354
L +LS KT+ E+ + + L++QL N KL+ + +
Sbjct: 943 ALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNY 987
Score = 33.5 bits (73), Expect = 1.8
Identities = 50/200 (25%), Positives = 82/200 (41%), Gaps = 18/200 (9%)
Query: 48 DKTVAELKND--EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSA--- 102
DK +AEL+ + N + L + E+ E ND + +DS
Sbjct: 776 DKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKK 835
Query: 103 ----SELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
ELE RE++Q+ MV+ + + T + ++E+V E++ K +
Sbjct: 836 DDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKL 895
Query: 159 TKDNISI---KTLLDKLITKNETDINE-LRNSIKYLESVKSEYNTANEKLFEQLNNAVDK 214
+ S+ +T L L + + E L + L + SE AN L E L+++ K
Sbjct: 896 SSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISE-KDANIALLE-LSSSKKK 953
Query: 215 QNCIQEEVDLLKIENQNLLQ 234
QEEV LK E L+Q
Sbjct: 954 ---TQEEVAALKREKDRLVQ 970
>BC117132-1|AAI17133.1| 1306|Homo sapiens kinectin 1 (kinesin
receptor) protein.
Length = 1306
Score = 54.0 bits (124), Expect = 1e-06
Identities = 76/407 (18%), Positives = 162/407 (39%), Gaps = 40/407 (9%)
Query: 55 KNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQ 114
+N+ + + I+Q E + K +K+ + ASE + L + +
Sbjct: 577 QNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 636
Query: 115 MHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLIT 174
+ D+ + ++ + + + L N A E++ + S+ + I+ L ++L
Sbjct: 637 L--KDIQNMNFLLKAEVQKLQALAN---EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH 691
Query: 175 KNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQ--NCIQEEVDLLKIENQNL 232
+ + E + +++KSE + EQ N V +Q CIQE+ + LK + L
Sbjct: 692 EISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELL 751
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM---------LVEEKLSEIKEKDENFK 283
++++K LVEE I EKD K
Sbjct: 752 ETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIK 811
Query: 284 QEIDMLNEKL--ICDRRE-----FNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM 336
++L +L + ++ + +QE LL +++N + LEEK++ L +
Sbjct: 812 SVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTG 871
Query: 337 EQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHI 396
+ L D + + E++ V ++A + L + S + +E + + L + N +
Sbjct: 872 KWLQDLQEEN----ESLKAHVQEVA-----QHNLK---EASSASQFEELEIVLKEKENEL 919
Query: 397 TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETEN 443
L + E + + L + + D+ ++N + K ++ QL+ +N
Sbjct: 920 KRLEAMLKERESD-----LSSKTQLLQDVQDENKLFKSQIEQLKQQN 961
Score = 48.8 bits (111), Expect = 5e-05
Identities = 64/342 (18%), Positives = 141/342 (41%), Gaps = 24/342 (7%)
Query: 20 HAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKN-DEINSMIRQLXXXXXXXXXXXX 78
H ++EE +K + L+ V V+E N D + M + +
Sbjct: 691 HEISNKMEE-FKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEE 749
Query: 79 XLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L L TK +L + +++S + + ++++ +D + +++ L +VI+
Sbjct: 750 LLETGLIQVATKEEELNAIRTENSSLTKEV--QDLKAKQNDQVSFASLVEELKKVIHEKD 807
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYN 198
+S+EE+ LE +L K + + + + IT + EL+N +K E +
Sbjct: 808 GKIKSVEEL-LEAELLKVANKEKTVQLS------ITSK---VQELQNLLKGKEEQMNTMK 857
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
E+ + L N +QEE + LK Q + Q +
Sbjct: 858 AVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKEN 917
Query: 259 NLEEMKTMLVEEK---------LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNI 309
L+ ++ ML E + L +++++++ FK +I+ L ++ F +E
Sbjct: 918 ELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSF-PPHEELLK 976
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIE 351
++S+ K+++ EL+ ++ + H ++ ND +++ +E
Sbjct: 977 VISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAME 1018
Score = 40.7 bits (91), Expect = 0.012
Identities = 68/314 (21%), Positives = 133/314 (42%), Gaps = 27/314 (8%)
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD----KFIANLEEMKTM 266
A ++ +E +L I+N N L A + + +++ K
Sbjct: 624 ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIR 683
Query: 267 LVEEKLS-EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK--VNKTER 323
L+EE+L EI K E FK +LN++ + +Q+ L+S+ K V + E+
Sbjct: 684 LLEEQLQHEISNKMEEFK----ILNDQ----NKALKSEVQKLQTLVSEQPNKDVVEQMEK 735
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
++EK E+L +E+L +T LI+ + K ++ + ++ L+ E+ D +
Sbjct: 736 CIQEKDEKLK-TVEELLETG-----LIQ-VATKEEELNAIRTENSSLTKEVQDLKAKQND 788
Query: 384 RISLT--LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK-ERLSQLE 440
++S ++++ I + +I ++ A+LL A K+ + +I K + L L
Sbjct: 789 QVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE--KTVQLSITSKVQELQNLL 846
Query: 441 TENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
+E + ++ V E+ N E+ K SQFE
Sbjct: 847 KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFE 906
Query: 501 DLDDVMKQQQKELK 514
+L+ V+K+++ ELK
Sbjct: 907 ELEIVLKEKENELK 920
>BC112337-1|AAI12338.1| 1306|Homo sapiens kinectin 1 (kinesin
receptor) protein.
Length = 1306
Score = 54.0 bits (124), Expect = 1e-06
Identities = 76/407 (18%), Positives = 162/407 (39%), Gaps = 40/407 (9%)
Query: 55 KNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQ 114
+N+ + + I+Q E + K +K+ + ASE + L + +
Sbjct: 577 QNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 636
Query: 115 MHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLIT 174
+ D+ + ++ + + + L N A E++ + S+ + I+ L ++L
Sbjct: 637 L--KDIQNMNFLLKAEVQKLQALAN---EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH 691
Query: 175 KNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQ--NCIQEEVDLLKIENQNL 232
+ + E + +++KSE + EQ N V +Q CIQE+ + LK + L
Sbjct: 692 EISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELL 751
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM---------LVEEKLSEIKEKDENFK 283
++++K LVEE I EKD K
Sbjct: 752 ETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIK 811
Query: 284 QEIDMLNEKL--ICDRRE-----FNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM 336
++L +L + ++ + +QE LL +++N + LEEK++ L +
Sbjct: 812 SVEELLEAELLKVANKEKTVQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTG 871
Query: 337 EQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHI 396
+ L D + + E++ V ++A + L + S + +E + + L + N +
Sbjct: 872 KWLQDLQEEN----ESLKAHVQEVA-----QHNLK---EASSASQFEELEIVLKEKENEL 919
Query: 397 TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETEN 443
L + E + + L + + D+ ++N + K ++ QL+ +N
Sbjct: 920 KRLEAMLKERESD-----LSSKTQLLQDVQDENKLFKSQIEQLKQQN 961
Score = 48.8 bits (111), Expect = 5e-05
Identities = 64/342 (18%), Positives = 141/342 (41%), Gaps = 24/342 (7%)
Query: 20 HAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKN-DEINSMIRQLXXXXXXXXXXXX 78
H ++EE +K + L+ V V+E N D + M + +
Sbjct: 691 HEISNKMEE-FKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEE 749
Query: 79 XLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L L TK +L + +++S + + ++++ +D + +++ L +VI+
Sbjct: 750 LLETGLIQVATKEEELNAIRTENSSLTKEV--QDLKAKQNDQVSFASLVEELKKVIHEKD 807
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYN 198
+S+EE+ LE +L K + + + + IT + EL+N +K E +
Sbjct: 808 GKIKSVEEL-LEAELLKVANKEKTVQLS------ITSK---VQELQNLLKGKEEQMNTMK 857
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
E+ + L N +QEE + LK Q + Q +
Sbjct: 858 AVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKEN 917
Query: 259 NLEEMKTMLVEEK---------LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNI 309
L+ ++ ML E + L +++++++ FK +I+ L ++ F +E
Sbjct: 918 ELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQASSF-PPHEELLK 976
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIE 351
++S+ K+++ EL+ ++ + H ++ ND +++ +E
Sbjct: 977 VISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAME 1018
Score = 40.7 bits (91), Expect = 0.012
Identities = 68/314 (21%), Positives = 133/314 (42%), Gaps = 27/314 (8%)
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD----KFIANLEEMKTM 266
A ++ +E +L I+N N L A + + +++ K
Sbjct: 624 ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIR 683
Query: 267 LVEEKLS-EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK--VNKTER 323
L+EE+L EI K E FK +LN++ + +Q+ L+S+ K V + E+
Sbjct: 684 LLEEQLQHEISNKMEEFK----ILNDQ----NKALKSEVQKLQTLVSEQPNKDVVEQMEK 735
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
++EK E+L +E+L +T LI+ + K ++ + ++ L+ E+ D +
Sbjct: 736 CIQEKDEKLK-TVEELLETG-----LIQ-VATKEEELNAIRTENSSLTKEVQDLKAKQND 788
Query: 384 RISLT--LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK-ERLSQLE 440
++S ++++ I + +I ++ A+LL A K+ + +I K + L L
Sbjct: 789 QVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKE--KTVQLSITSKVQELQNLL 846
Query: 441 TENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
+E + ++ V E+ N E+ K SQFE
Sbjct: 847 KGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQFE 906
Query: 501 DLDDVMKQQQKELK 514
+L+ V+K+++ ELK
Sbjct: 907 ELEIVLKEKENELK 920
>AB053471-1|BAC54110.1| 1116|Homo sapiens ELKS epsilon protein.
Length = 1116
Score = 54.0 bits (124), Expect = 1e-06
Identities = 93/439 (21%), Positives = 187/439 (42%), Gaps = 38/439 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L E+L+ E + +LKK +E+ +K+E + T E++ +L + TLTN
Sbjct: 443 LKEELSSKEAQWEELKKKAAGLQAEIGQVKQELSRKDT-------ELL-ALQTKLETLTN 494
Query: 140 GFESLEEVALEIDLKKNSIT-KDNIS--IKTLLDKLITKNETDINELRNSIKYLESVKSE 196
F ++ I++ K S+T K+ + ++T +D L + E L K ++ + E
Sbjct: 495 QFSDSKQ---HIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMAEE 551
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
T ++ + L + +D + + +V++L+ + +NL + +
Sbjct: 552 KGTQAGEIHD-LKDMLDVK---ERKVNVLQKKIENLQEQLRDKEKQMSSLKERVKSLQAD 607
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
N + T L EE L+E + E K++ D D RE E + L DL +
Sbjct: 608 TTNTDTALTTL-EEALAEKERTIERLKEQRDR-------DEREKQEEIDNYKKDLKDLKE 659
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
KV+ + +L EK+ L L E + ++ K + K +IA + K L E
Sbjct: 660 KVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSRL--KTLEIALEQKKEECLKMESQL 717
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERL 436
+ + + ++++ I +L +I T+ D + +A+ ++ L E ILKE
Sbjct: 718 KKAHEAALEARASPEMSDRIQHLEREI--TRYKDESS---KAQAEVDRLLE---ILKEVE 769
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED-MKTKVMEW 495
++ ++K++ + V+ N++V NLK + ED + +
Sbjct: 770 NEKNDKDKKIAELERQVKDQNKKVA-NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQL 828
Query: 496 KSQFEDLDDVMKQQQKELK 514
+ DD +++ ++ L+
Sbjct: 829 QDSLRKKDDRIEELEEALR 847
Score = 48.8 bits (111), Expect = 5e-05
Identities = 67/379 (17%), Positives = 158/379 (41%), Gaps = 12/379 (3%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++LEE+ L I+ +K ++ + SIK LL+ L +K + + + ++E + +
Sbjct: 286 KTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHH 345
Query: 202 -EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L EQ +K+N + E + EN + ++ + +L
Sbjct: 346 LESLLEQ----KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDL 401
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDR-REFNETMQEKNILLSDLSKKV 318
EE ML +E++E KQ E+ + K + ++ + E + K +L KK
Sbjct: 402 EEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKVEQLKEELSSKEAQWEELKKKA 461
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ E+ + +++L+ +L + + + N F+ Q K S +
Sbjct: 462 AGLQAEIGQVKQELSRKDTELLALQ-TKLETLTNQFSDSKQHIEVLKESLTAKEQRAAIL 520
Query: 379 ENTYERISLTLDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
+ + + L L++ + QI + +K A + + K + D+ E+ + +L+++
Sbjct: 521 QTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLKDML-DVKERKVNVLQKK 579
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
+ L+ + ++ ++ +++ + + + ++ T IE +K +
Sbjct: 580 IENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTLEEALAEKERTIERLKEQRDRD 639
Query: 496 KSQFEDLDDVMKQQQKELK 514
+ + ++ D K+ K+LK
Sbjct: 640 EREKQEEIDNYKKDLKDLK 658
Score = 44.0 bits (99), Expect = 0.001
Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 12/225 (5%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVK---SEYN 198
E L+EV E + K I + +K K+ + E + S + LE + N
Sbjct: 763 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLN 822
Query: 199 TANEKLFEQLNNAVDK----QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
++++L + L D+ + ++E V + L Q A +
Sbjct: 823 DSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 882
Query: 255 KFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDM-LNEKLICDRREFNETMQEK--NI 309
K LE MK L ++ L+E + N + E L E L + + EK NI
Sbjct: 883 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 942
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF 354
L +LS KT+ E+ + + L++QL N KL+ + +
Sbjct: 943 ALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNY 987
Score = 33.5 bits (73), Expect = 1.8
Identities = 50/200 (25%), Positives = 82/200 (41%), Gaps = 18/200 (9%)
Query: 48 DKTVAELKND--EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSA--- 102
DK +AEL+ + N + L + E+ E ND + +DS
Sbjct: 776 DKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKK 835
Query: 103 ----SELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
ELE RE++Q+ MV+ + + T + ++E+V E++ K +
Sbjct: 836 DDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKL 895
Query: 159 TKDNISI---KTLLDKLITKNETDINE-LRNSIKYLESVKSEYNTANEKLFEQLNNAVDK 214
+ S+ +T L L + + E L + L + SE AN L E L+++ K
Sbjct: 896 SSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISE-KDANIALLE-LSSSKKK 953
Query: 215 QNCIQEEVDLLKIENQNLLQ 234
QEEV LK E L+Q
Sbjct: 954 ---TQEEVAALKREKDRLVQ 970
>AB002334-1|BAA20794.2| 1635|Homo sapiens KIAA0336 protein.
Length = 1635
Score = 54.0 bits (124), Expect = 1e-06
Identities = 78/388 (20%), Positives = 162/388 (41%), Gaps = 35/388 (9%)
Query: 120 VMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETD 179
V V+ + +SL ++ N +E LE++ + + ++++ L L+ E +
Sbjct: 731 VNVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQE 790
Query: 180 INELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXX 239
LR K LE ++SE L E + NA +K ++ENQNLL
Sbjct: 791 KVLLR---KELEEIQSEKEALQSDLLE-MKNANEKT----------RLENQNLLIQVEEV 836
Query: 240 XXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRRE 299
FI E +K +L E+K E++++ + E+ +L + L
Sbjct: 837 SQTCSKSEIHNEKEKCFIKEHENLKPLL-EQK--ELRDR----RAELILLKDSLAKSPSV 889
Query: 300 FNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL---MEQLNDTENNSYKLIENMFNK 356
N+ + + +L +K+ E+E +EK+E++ + + ++S K + + +
Sbjct: 890 KNDPLSS----VKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKETQTVKEE 945
Query: 357 VSQIASDFKISNQLSCELDD--ESENTYERISLTLDKITNHITYLNTQIN--ETQKNDNA 412
+ + S+ +QLS + D + +Y+ + L +K + + + N E + D
Sbjct: 946 LESLRSE---KDQLSASMRDLIQGAESYKNLLLEYEKQSEQLDVEKERANNFEHRIEDLT 1002
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
+ L + Q + N L R+ L++ K L ++I V+ + V L+
Sbjct: 1003 RQLRNSTLQCETINSDNEDLLARIETLQSNAKLLEVQILEVQRAKAMVDKELEAEKLQKE 1062
Query: 473 XXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
NE+E+++ ++ + K Q +
Sbjct: 1063 QKIKEHATTVNELEELQVQLQKEKKQLQ 1090
Score = 50.8 bits (116), Expect = 1e-05
Identities = 87/381 (22%), Positives = 172/381 (45%), Gaps = 40/381 (10%)
Query: 99 EDSASELEALKRENIQMHTSDVMVVPE--IIDSLTEVINTLTNGFESLEEVALEIDLKKN 156
E E+++LK + H ++ + E + DS E + TL + L+E + +K
Sbjct: 371 EQHNREVQSLKEQ----HQKEISELNETFLSDSEKEKL-TLMFEIQGLKEQCENLQQEKQ 425
Query: 157 SITKDNISIKTLLDKLITKNETDINELRNSIKY-LESVKSEYNTANEKLFEQLNNAVDKQ 215
+ S++ +++ L +T++ E I ES+K + + +L ++L A ++
Sbjct: 426 EAILNYESLREIMEIL----QTELGESAGKISQEFESMKQQQASDVHELQQKLRTAFTEK 481
Query: 216 NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML--VEEKLS 273
+ + E V+ L+ EN+ LL ++ +L + TML +E K++
Sbjct: 482 DALLETVNRLQGENEKLLSQQELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEGKIN 541
Query: 274 EI-KEKDE-------------NFKQEIDMLNEKLICD-RREFNETMQEKNILLSDLSKKV 318
+ +EKD+ NF ++ + E+LI + ++ +T+Q S+L +KV
Sbjct: 542 SLTEEKDDFINKLKNSHEEMDNFHKKCER-EERLILELGKKVEQTIQYN----SELEQKV 596
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
N+ LEE ++ ++L L E+ +++ S ++ +N+LS E S
Sbjct: 597 NELTGGLEETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSEKKQLS 656
Query: 379 ENTYERISLTLDKI-TNHITYLNTQIN---ETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ +S D I HIT L ++ E Q N N L E +++ T+ LKE
Sbjct: 657 RDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLYGFLKE 716
Query: 435 RLSQL--ETENKELLIEIQTV 453
S++ ++E K+++ +Q V
Sbjct: 717 MGSEVSEDSEEKDVVNVLQAV 737
Score = 50.4 bits (115), Expect = 1e-05
Identities = 78/423 (18%), Positives = 171/423 (40%), Gaps = 43/423 (10%)
Query: 126 IIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITK--------NE 177
+ + ++I LT ++L E + + S+ K+NI +K ++ +TK +
Sbjct: 14 VTEGTGDIIKALTERLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQ 73
Query: 178 TDIN---ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
+ IN E+ N L +V+S+Y+ L +QL A++ Q + E++ N+ +
Sbjct: 74 SHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKK 133
Query: 235 XXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLI 294
K + + K V + + I+ +++++ I+ L E+L+
Sbjct: 134 LQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELL 193
Query: 295 CDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF 354
+ E ++E L+ + + E E+ + E +L++Q +E N K E
Sbjct: 194 QLKAIHQEEVKE---LMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECEL 250
Query: 355 NKVSQIASDFKISNQLSCELDDES--------------ENTYERISLTLDKITNHITYLN 400
+ + S+ NQ+ L E+ E+T + + + + +TY+N
Sbjct: 251 ENLRKATSNANQDNQICSILLQENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMN 310
Query: 401 T----------QINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEI 450
I + ++ L ++ + + EQ ++++ S+L NK+
Sbjct: 311 NLKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQF---C 367
Query: 451 QTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQ 510
TV N EV +LK+ +E E + T + E + E +++ +++Q
Sbjct: 368 YTVEQHNREVQ-SLKEQHQKEISELNETFLSDSEKEKL-TLMFEIQGLKEQCENLQQEKQ 425
Query: 511 KEL 513
+ +
Sbjct: 426 EAI 428
Score = 50.0 bits (114), Expect = 2e-05
Identities = 79/379 (20%), Positives = 149/379 (39%), Gaps = 21/379 (5%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDL 153
LK ++++ EL + + H +++ + E+ ++L + + E LE
Sbjct: 195 LKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLR 254
Query: 154 KKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ---LNN 210
K S + I ++L + T E +NE +K+LE E + + L ++ +NN
Sbjct: 255 KATSNANQDNQICSILLQENTFVEQVVNE---KVKHLEDTLKELESQHSILKDEVTYMNN 311
Query: 211 AVDKQNCIQEEV-DLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
K + + D E ++L +A L + VE
Sbjct: 312 LKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVE 371
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
+ E++ E ++EI LNE + D + T+ + L + + + + ++E
Sbjct: 372 QHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILNY 431
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKV-SQIASDFKISNQLSCELDDESENTYERISLT 388
E L +ME L S I F + Q ASD EL + +
Sbjct: 432 ESLREIMEILQTELGESAGKISQEFESMKQQQASDVH-------ELQQKLRTAFTEKDAL 484
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLI 448
L+ + N + N ++ Q +L+ E + I +L E+N + LSQ +T KEL
Sbjct: 485 LETV-NRLQGENEKLLSQQ-----ELVPELENTIKNLQEKNGVYLLSLSQRDTMLKELEG 538
Query: 449 EIQTVRGSNEEVTLNLKDS 467
+I ++ ++ LK+S
Sbjct: 539 KINSLTEEKDDFINKLKNS 557
Score = 49.6 bits (113), Expect = 3e-05
Identities = 71/380 (18%), Positives = 158/380 (41%), Gaps = 27/380 (7%)
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E K N +K + + EL++ ++E Q ++ + D L+ + L G ES + +
Sbjct: 915 EEKINKIKLVAVKAKKELDSSRKET-QTVKEELESLRSEKDQLSASMRDLIQGAESYKNL 973
Query: 148 ALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
LE + + + + K + + E +LRNS E++ S+ NE L +
Sbjct: 974 LLEYEKQSEQLDVE----KERANNFEHRIEDLTRQLRNSTLQCETINSD----NEDLLAR 1025
Query: 208 LNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML 267
+ + N EV +L+++ + + LEE++ L
Sbjct: 1026 IETL--QSNAKLLEVQILEVQRAKAM-VDKELEAEKLQKEQKIKEHATTVNELEELQVQL 1082
Query: 268 VEEK--LSEIKEKDENFK---QEIDMLNEKLICDRR---EFNETMQEKNILLSDLSKKVN 319
+EK L + ++ E K Q+ ++N ++ R E N+ + KN + DL +++
Sbjct: 1083 QKEKKQLQKTMQELELVKKDAQQTTLMNMEIADYERLMKELNQKLTNKNNKIEDLEQEIK 1142
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ---LSCELDD 376
+++ E QE++T L + E + K+ + + ++A + L L
Sbjct: 1143 IQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLKG 1202
Query: 377 ESENTYERI---SLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
E E + +++ + L +IT+ ++ + +T + + L ++++ L E+ K
Sbjct: 1203 ELEASQQQVEVYKIQLAEITSEKHKIHEHL-KTSAEQHQRTLSAYQQRVTALQEECRAAK 1261
Query: 434 ERLSQLETENKELLIEIQTV 453
+ + +E + + + V
Sbjct: 1262 AEQATVTSEFESYKVRVHNV 1281
Score = 44.4 bits (100), Expect = 0.001
Identities = 89/419 (21%), Positives = 170/419 (40%), Gaps = 29/419 (6%)
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTL--TNGFESLE 145
E K N+L E++ E + + ++ + V+ E + L+ + +L N S E
Sbjct: 593 EQKVNELTGGLEETLKEKDQ-NDQKLEKLMVQMKVLSEDKEVLSAEVKSLYEENNKLSSE 651
Query: 146 EVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLF 205
+ L DL+ K+++ +K + +L K + + E N K LE+ + + +L+
Sbjct: 652 KKQLSRDLEVFLSQKEDVILKEHITQLEKKLQLMVEEQDNLNKLLENEQVQKLFVKTQLY 711
Query: 206 EQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX-XXXXARDKFIANLEEMK 264
L + + EE D++ N+LQ RD+ + LE+
Sbjct: 712 GFLKEMGSEVSEDSEEKDVV-----NVLQAVGESLAKINEEKCNLAFQRDEKVLELEKEI 766
Query: 265 TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
L EE + + +E + D EK++ R+E E EK L SDL + N E+
Sbjct: 767 KCLQEESVVQCEELKSLLR---DYEQEKVLL-RKELEEIQSEKEALQSDLLEMKNANEKT 822
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYER 384
E Q L +E+++ T + S I N K F ++ L ++ E R
Sbjct: 823 RLENQNLLIQ-VEEVSQTCSKSE--IHNEKEKC------FIKEHENLKPLLEQKELRDRR 873
Query: 385 ISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENK 444
L L K + + + KND + E +++I +L ++ +E++++++
Sbjct: 874 AELILLKD-------SLAKSPSVKNDPLSSVKELEEKIENLEKECKEKEEKINKIKLVAV 926
Query: 445 ELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLD 503
+ E+ + R + V L+ + E K ++E++ Q E LD
Sbjct: 927 KAKKELDSSRKETQTVKEELESLRSEKDQLSASMRDLIQGAESYKNLLLEYEKQSEQLD 985
Score = 39.9 bits (89), Expect = 0.021
Identities = 97/473 (20%), Positives = 191/473 (40%), Gaps = 46/473 (9%)
Query: 13 ENIRNIIHAFKIRLEECYKEIGQLKSGLQQ----NVGVGD------KTVAELKNDEINSM 62
E++ I K + E +EI L+S +QQ N + K +A+ K E + +
Sbjct: 1135 EDLEQEIKIQKQKQETLQEEITSLQSSVQQYEEKNTKIKQLLVKTKKELADSKQAETDHL 1194
Query: 63 IRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMV 122
I Q K+ +AE ++ K++E + E +R + + V
Sbjct: 1195 ILQASLKGELEASQQQVEVYKIQLAEIT-SEKHKIHEHLKTSAEQHQR-TLSAYQQRVTA 1252
Query: 123 VPEIIDSLTEVINTLTNGFESLE-EVALEIDLKKNS---------ITKDNISIKTLLDKL 172
+ E + T+T+ FES + V + +KN ++ ++ L+D+L
Sbjct: 1253 LQEECRAAKAEQATVTSEFESYKVRVHNVLKQQKNKSMSQAETEGAKQEREHLEMLIDQL 1312
Query: 173 ITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL 232
K + N L+ ++ L++++SE++T E+ + L V K+ ++E+ L I+++N+
Sbjct: 1313 KIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSKEAELREK--LCSIQSENM 1370
Query: 233 LQXXXXXXXXXXXXXXXXXARDKF---IANLEEMKTMLVEEKLSEI-KEKDENFKQEIDM 288
+ R+ F + +L+E VE ++ K + + F+ + +
Sbjct: 1371 MMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQLSKMEAQLFQLKNEP 1430
Query: 289 LNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
+ ++ + +N L L ++ RE E E T E ++ +
Sbjct: 1431 TTRSPVSSQQSLKNLRERRNTDLPLLD--MHTVTREEGEGME--TTDTESVSSASTYTQS 1486
Query: 349 LIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQK 408
L E + N + + K+ L +E T E + L T +LN + ET+
Sbjct: 1487 L-EQLLN-----SPETKLEPPLW-----HAEFTKEELVQKLSSTTKSADHLNGLLRETEA 1535
Query: 409 NDNAQLLWEAKKQIADL--TEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
NA L+ + K +++ E+N ++ + LE LL I GS E
Sbjct: 1536 T-NAILMEQIKLLKSEIRRLERNQEREKSAANLEYLKNVLLQFIFLKPGSERE 1587
Score = 38.7 bits (86), Expect = 0.049
Identities = 70/390 (17%), Positives = 143/390 (36%), Gaps = 14/390 (3%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
++ T+ + D ++L ++ +L K I+ ++ + + ++L E I +L +
Sbjct: 1104 QQTTLMNMEIADYERLMKELNQKLTN-KNNKIEDLEQEIKIQKQKQETLQEEITSLQSSV 1162
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTL-LDKLITKNETDINELRNSIKYLESVK---SEY 197
+ EE +I K+ K D LI + EL S + +E K +E
Sbjct: 1163 QQYEEKNTKIKQLLVKTKKELADSKQAETDHLILQASLK-GELEASQQQVEVYKIQLAEI 1221
Query: 198 NTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFI 257
+ K+ E L + ++ Q + R +
Sbjct: 1222 TSEKHKIHEHLKTSAEQHQRTLSAYQQRVTALQEECRAAKAEQATVTSEFESYKVRVHNV 1281
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
++ K+M E K++ E+ + ID L KL + + E L S+
Sbjct: 1282 LKQQKNKSMSQAET-EGAKQEREHLEMLIDQLKIKLQDSQNNLQINVSELQTLQSEHDTL 1340
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQLSCE--- 373
+ + + L+E + L E+L ++ + + VSQ+ S ++ N +
Sbjct: 1341 LERHNKMLQETVSKEAELREKLCSIQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRH 1400
Query: 374 LDDESENTYERISLTLDKITNHITYLN---TQINETQKNDNAQLLWEAKKQIADLTEQNI 430
L +E T E + L K+ + L T + + + L E + L + +
Sbjct: 1401 LQEEHRKTVETLQQQLSKMEAQLFQLKNEPTTRSPVSSQQSLKNLRERRNTDLPLLDMHT 1460
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEV 460
+ +E +ET + E + T S E++
Sbjct: 1461 VTREEGEGMETTDTESVSSASTYTQSLEQL 1490
Score = 38.3 bits (85), Expect = 0.065
Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 20/195 (10%)
Query: 268 VEEKLSEIKEKD--ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
+E+++ E++ K E I L E+L E ET Q+ LS L K+ K ++E+
Sbjct: 2 LEKEIEELRSKPVTEGTGDIIKALTERLDALLLEKAETEQQ---CLS-LKKENIKMKQEV 57
Query: 326 EEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI 385
E+ ++ ++L + N K IEN+ N++ + S + + +E+ NT +
Sbjct: 58 EDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLEL 117
Query: 386 SLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI-ADLTEQNIILKERLSQLETENK 444
S L K N+ DN + L E ++I EQ + L+++L E K
Sbjct: 118 SEQL-KFQNN------------SEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKK 164
Query: 445 ELLIEIQTVRGSNEE 459
E + ++Q + +N +
Sbjct: 165 ETVTQLQNIIEANSQ 179
Score = 37.9 bits (84), Expect = 0.085
Identities = 77/433 (17%), Positives = 177/433 (40%), Gaps = 32/433 (7%)
Query: 107 ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIK 166
+LK+ENI+M V ++ D+ E+ + N + +E + E+ ++ ++D +++
Sbjct: 45 SLKKENIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQ 104
Query: 167 TLLDKLITKNETDINELR---NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVD 223
L++ + +L+ NS ++ ++ E EQ+ + + +E
Sbjct: 105 KQLEEAMNTQLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKK 164
Query: 224 LLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLV---------EEKLSE 274
+ QN+++ + K I + EE+K ++ E ++++
Sbjct: 165 ETVTQLQNIIEANSQHYQKNINSLQEELLQLKAI-HQEEVKELMCQIEASAKEHEAEINK 223
Query: 275 IKEKDENFKQEIDM----LNEKLICD---RREFNETMQEKNILLSDLSKKVNKTERELEE 327
+ E EN ++ + + +K C+ R+ + N + S L ++ E+ + E
Sbjct: 224 LNELKENLVKQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQENTFVEQVVNE 283
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK-ISNQLSCELDD------ESEN 380
K + L +++L + + M N ++ D + I ++ E +D E
Sbjct: 284 KVKHLEDTLKELESQHSILKDEVTYMNNLKLKLEMDAQHIKDEFFHEREDLEFKINELLL 343
Query: 381 TYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
E ++K+ + + LN Q T + N ++ ++ +++E N + LS E
Sbjct: 344 AKEEQGCVIEKLKSELAGLNKQFCYTVEQHNREVQSLKEQHQKEISELN---ETFLSDSE 400
Query: 441 TENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKV-MEWKS-Q 498
E L+ EIQ ++ E + +++ E+ + K+ E++S +
Sbjct: 401 KEKLTLMFEIQGLKEQCENLQQEKQEAILNYESLREIMEILQTELGESAGKISQEFESMK 460
Query: 499 FEDLDDVMKQQQK 511
+ DV + QQK
Sbjct: 461 QQQASDVHELQQK 473
>BC117690-1|AAI17691.1| 1976|Homo sapiens myosin, heavy chain 10,
non-muscle protein.
Length = 1976
Score = 53.6 bits (123), Expect = 2e-06
Identities = 78/440 (17%), Positives = 180/440 (40%), Gaps = 29/440 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K +E K ++++ +++L L EK + + + +++ L E++ +
Sbjct: 1247 KAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKF 1306
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNISIK 166
++ + S + E++ T L++ LEE +L+ ++ + N+ +
Sbjct: 1307 AKDAASLE-SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQ 1365
Query: 167 TL-LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNCI 218
L L + + +++ +I+ LE K + E L ++L A DK +N +
Sbjct: 1366 VLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRL 1425
Query: 219 QEEVDLLKIENQNLLQXXXXX-----------XXXXXXXXXXXXARDKFIANLEEMKTML 267
Q+E D L ++ + Q RD+ A E +T
Sbjct: 1426 QQEPDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKA 1485
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEE 327
+ L+ E+ K+E + N++L D + + + + +L K E+++EE
Sbjct: 1486 LS--LARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEE 1543
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
+ QL L ++L TE+ +L NM +Q D + ++ + +++ +++
Sbjct: 1544 MRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDE---QNEEKKRLLIKQVRE 1600
Query: 388 TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
++ + + +K + EA+ + A+ +I ++L +L+ + K+
Sbjct: 1601 LEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVI--KQLRKLQAQMKDYQ 1658
Query: 448 IEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K+S
Sbjct: 1659 RELEEARASRDEIFAQSKES 1678
Score = 45.2 bits (102), Expect = 6e-04
Identities = 69/352 (19%), Positives = 142/352 (40%), Gaps = 17/352 (4%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
L K+ K E I++L +K E + E A KL + + D+ +Q ++D LK++
Sbjct: 1025 LAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQ 1084
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDM 288
+ K + L+ L E+ SE +++ KQ+ D
Sbjct: 1085 LAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRD- 1143
Query: 289 LNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLME-QLNDTENNSY 347
L+E+L + E +T+ + +L K + EL++ E+ T E Q+ D
Sbjct: 1144 LSEELEALKTELEDTL-DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHA 1202
Query: 348 KLIENMFNKVSQIASDFKIS---NQLSCELDDESENTYERISLTLDKITNH-ITYLNTQI 403
+E + ++ Q A FK + N+ E D++ ++ + + H L+ Q+
Sbjct: 1203 TALEELSEQLEQ-AKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQV 1261
Query: 404 NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL- 462
E + E + +L E+ L+ L + T +E E + ++ + + +L
Sbjct: 1262 QELHAK-----VSEGDRLRVELAEKASKLQNELDNVSTLLEE--AEKKGIKFAKDAASLE 1314
Query: 463 -NLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
L+D+ S+ I ++ + + Q E+ ++ K +K++
Sbjct: 1315 SQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQV 1366
Score = 45.2 bits (102), Expect = 6e-04
Identities = 73/330 (22%), Positives = 131/330 (39%), Gaps = 34/330 (10%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + N ++ ++ L++ + +++EL S + LE E T E+
Sbjct: 1491 ALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE 1550
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + +K + + LQ + I + E+
Sbjct: 1551 LEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEK---------KRLLIKQVREL 1601
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+ L +E+ K EID+ + L N+ E L L ++ +R
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDL--KDLEAQIEAANKARDEVIKQLRKLQAQMKDYQR 1659
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI---SNQLSCELDDESEN 380
ELEE + + Q ++E L + ++AS + + Q EL DE N
Sbjct: 1660 ELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719
Query: 381 TYERISLTLD---KITNHITYLNTQINETQKNDNAQLLWEA-KKQIADLTEQNIILKERL 436
+ S LD ++ I L ++ E Q N +LL + +K + N L
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSN--MELLNDRFRKTTLQVDTLNAELAAER 1777
Query: 437 S----------QLETENKELLIEIQTVRGS 456
S QLE +NKEL ++Q + G+
Sbjct: 1778 SAAQKSDNARQQLERQNKELKAKLQELEGA 1807
Score = 44.8 bits (101), Expect = 7e-04
Identities = 103/520 (19%), Positives = 208/520 (40%), Gaps = 54/520 (10%)
Query: 14 NIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXX 73
++++ I + +++E ++ + + LQ + GD KN+ + ++R+L
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLH-KNNALK-VVRELQAQIAEL 1123
Query: 74 XXXXXXLTEKLTIAETKHNDLKKLYEDSASELE------ALKRENIQMHTSDVMVVPEII 127
AE + DL + E +ELE A ++E +V + + +
Sbjct: 1124 QEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKAL 1183
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+ T+ ALE +L + + K L+K ETD EL +
Sbjct: 1184 EEETKNHEAQIQDMRQRHATALE-ELSEQ--LEQAKRFKANLEKNKQGLETDNKELACEV 1240
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
K L+ VK+E +KL Q V + + E D L++E
Sbjct: 1241 KVLQQVKAESEHKRKKLDAQ----VQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLL 1296
Query: 248 XXXXARD-KFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEK--LICDRREFNE 302
+ KF + +++ L +E L E + N I L E+ + +++E E
Sbjct: 1297 EEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEE 1356
Query: 303 TMQ---EKNIL-----LSDLSKKVNK---TERELEEKQEQLTHLMEQLN---DTENNSYK 348
+ EK +L L+D KKV+ T LEE +++L E L+ + + +Y
Sbjct: 1357 EARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYD 1416
Query: 349 LIENMFNKVSQIASDFKISNQLSCELDDESE--NTYERISLTLDKITNHITYLNTQINET 406
+E N++ Q D L+ +LD + + + E+ D++ ++ + E
Sbjct: 1417 KLEKTKNRLQQEPDD------LTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEE 1470
Query: 407 QKNDNAQLLWEAKK--QIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNL 464
+ A+ + K +A E+ + KE + E +NK+L +++ + S ++V N+
Sbjct: 1471 RDRAEAEAREKETKALSLARALEEALEAKE---EFERQNKQLRADMEDLMSSKDDVGKNV 1527
Query: 465 KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDD 504
+ ++E+M+T++ E + + + +D
Sbjct: 1528 HE-------LEKSKRALEQQVEEMRTQLEELEDELQATED 1560
Score = 44.4 bits (100), Expect = 0.001
Identities = 89/474 (18%), Positives = 193/474 (40%), Gaps = 64/474 (13%)
Query: 88 ETKHNDLKKLYEDSAS---ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+ K +L K+ E ELE ++R++ Q+ + ++ E + + TE+ F
Sbjct: 855 QAKDEELLKVKEKQTKVEGELEEMERKHQQL-LEEKNILAEQLQAETEL-------FAEA 906
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINE---LRNSIKYLESVKSEYNTAN 201
EE+ + KK + + +++ +++ +N+ NE ++ I+ LE E A
Sbjct: 907 EEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
+KL + A K ++EE+ LL+ +N ++ E
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAE--------E 1018
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
E K + L++I+ K E +++ +K R+E + ++ + +DL ++ +
Sbjct: 1019 EEKA----KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 322 ERELEEKQEQLTHLMEQL------NDTE----NNSYKLIENMFNKVSQIASDFKI----- 366
+ +++E + QL E+L D E NN+ K++ + +++++ DF+
Sbjct: 1075 QAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASR 1134
Query: 367 --SNQLSCELDDESENTYERISLTLD----------KITNHITYLNTQINETQKNDNAQL 414
+ + +L +E E + TLD K + L + E KN AQ+
Sbjct: 1135 NKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQI 1194
Query: 415 ----------LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNL 464
L E +Q+ L++ LET+NKEL E++ ++ E
Sbjct: 1195 QDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR 1254
Query: 465 KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE-LKLGK 517
K ++ K + +++ +++ ++++ +K+ +K K
Sbjct: 1255 KKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAK 1308
Score = 43.2 bits (97), Expect = 0.002
Identities = 75/368 (20%), Positives = 146/368 (39%), Gaps = 33/368 (8%)
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLL 225
K L++ + + T + EL + ++ E K + + Q + ++ EE L
Sbjct: 1534 KRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRL 1593
Query: 226 KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQE 285
I+ L+ ++ K +L++++ + K +DE KQ
Sbjct: 1594 LIKQVRELEAELEDERKQRALAVA--SKKKMEIDLKDLEAQIEAAN----KARDEVIKQ- 1646
Query: 286 IDMLNEKLICDRREFNETMQEKNILLS---DLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
+ L ++ +RE E ++ + + + KK+ E E+ + QE+L
Sbjct: 1647 LRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHA 1706
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSC---ELDDESENTYERISLTLD---KITNHI 396
E +L + + N S ++ +L +L++E E + L D K T +
Sbjct: 1707 EQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQV 1766
Query: 397 TYLNTQI----NETQKNDNA--QLLWEAKKQIADLTEQNIILKER----LSQLETENKEL 446
LN ++ + QK+DNA QL + K+ A L E +K + +S LE + +L
Sbjct: 1767 DTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQL 1826
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVM 506
E Q + + E N T ++ED + ++K Q E + M
Sbjct: 1827 --EEQLEQEAKERAAANKLVRRTEKKLKEIFM-----QVEDERRHADQYKEQMEKANARM 1879
Query: 507 KQQQKELK 514
KQ +++L+
Sbjct: 1880 KQLKRQLE 1887
Score = 40.7 bits (91), Expect = 0.012
Identities = 66/384 (17%), Positives = 154/384 (40%), Gaps = 20/384 (5%)
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTS--DVMVVPEIIDSLTEVINTLTNGFES-L 144
ETK L + E++ E +R+N Q+ D+M + + + E +
Sbjct: 1482 ETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQV 1541
Query: 145 EEVALEIDLKKNSI--TKD-NISIKTLLDKLITKNETDIN--ELRNSIKYLESVKSEYNT 199
EE+ +++ ++ + T+D + ++ + + + E D+ + +N K +K
Sbjct: 1542 EEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVREL 1601
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E E+ A+ + + E+DL +E Q +D +
Sbjct: 1602 EAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKD-YQRE 1660
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQ---EIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
LEE + +E ++ KE ++ K EI L E+L R QE++ L +++
Sbjct: 1661 LEEARASR-DEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITN 1719
Query: 317 KVNKTERELEEK---QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
+ L+EK + ++ L E+L + ++N +L+ + F K +
Sbjct: 1720 SASGKSALLDEKRRLEARIAQLEEELEEEQSN-MELLNDRFRKTTLQVDTLNAELAAERS 1778
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQL---LWEAKKQIADLTEQNI 430
+S+N +++ ++ + L + K + L + + ++Q+ ++
Sbjct: 1779 AAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 1838
Query: 431 ILKERLSQLETENKELLIEIQTVR 454
+ + + E + KE+ ++++ R
Sbjct: 1839 AANKLVRRTEKKLKEIFMQVEDER 1862
Score = 37.1 bits (82), Expect = 0.15
Identities = 49/259 (18%), Positives = 106/259 (40%), Gaps = 20/259 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
+E + +E+L ++KEK + E++ + R+ + ++EKNIL L + +
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEME-------RKHQQLLEEKNILAEQLQAE-TE 901
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE-SE 379
E EE + +L ++L + ++ +E + + ++ K +L+++ E
Sbjct: 902 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDE 961
Query: 380 NTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL 439
R L L+K+T + D + KK + D + E SQL
Sbjct: 962 EEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDR------IAECSSQL 1015
Query: 440 ETENKELLIEIQTVRGSNE----EVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
E +E + +R E ++ LK E D++ ++ E
Sbjct: 1016 -AEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAEL 1074
Query: 496 KSQFEDLDDVMKQQQKELK 514
++Q ++L + ++++EL+
Sbjct: 1075 QAQIDELKLQLAKKEEELQ 1093
Score = 35.9 bits (79), Expect = 0.34
Identities = 41/159 (25%), Positives = 73/159 (45%), Gaps = 15/159 (9%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQLSC--E 373
+V + E EL+ K E+L + E+ E +E M K Q+ + I + QL E
Sbjct: 846 QVTRQEEELQAKDEELLKVKEKQTKVEGE----LEEMERKHQQLLEEKNILAEQLQAETE 901
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
L E+E R++ ++ + L +++ E ++ N L E KK A + + L+
Sbjct: 902 LFAEAEEMRARLAAKKQELEEILHDLESRVEEEEER-NQILQNEKKKMQAHIQD----LE 956
Query: 434 ERLSQLETENKELLIEIQTVRG---SNEEVTLNLKDSST 469
E+L + E ++L +E T EE L L+D ++
Sbjct: 957 EQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNS 995
>BC023634-1|AAH23634.2| 383|Homo sapiens IFT74 protein protein.
Length = 383
Score = 53.6 bits (123), Expect = 2e-06
Identities = 78/337 (23%), Positives = 150/337 (44%), Gaps = 44/337 (13%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
+SL+ + E K+ I I+ +K T + N +KYLE T N
Sbjct: 65 QSLDVIFTERQAKEKQIRSVEEEIEQ--EKQATDDIIKNMSFENQVKYLEM-----KTTN 117
Query: 202 EKLFEQLNNA---VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
EKL ++L+ +D QN +E ++ +I + + Q RD+ IA
Sbjct: 118 EKLLQELDTLQQQLDSQNMKKESLEA-EIAHSQVKQEAVLLHEKLYELESH---RDQMIA 173
Query: 259 NLEEMKTMLVEEKLSEIKE-KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK- 316
+ + + + EE+ +K+ KD+N QEI + +L + + N+ ++E L DL +
Sbjct: 174 EDKSIGSPM-EEREKLLKQIKDDN--QEIASMERQLTDTKEKINQFIEEIRQLDMDLEEH 230
Query: 317 --KVNKTERELEEKQEQLTHLMEQLNDTENNSYK-----------LIENMFNKVSQIASD 363
++N+ +EL++++E + +E +T+N K L+E+ +++I
Sbjct: 231 QGEMNQKYKELKKREEHMDTFIETFEETKNQELKRKAQIEANIVALLEHCSRNINRIEQI 290
Query: 364 FKISNQ-LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
I+NQ L DD + + E + K + L + I Q + L E+K
Sbjct: 291 SSITNQELKMMQDDLNFKSTE-----VQKSQSTAQNLTSDIQRLQLDLQKMELLESK--- 342
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
+TE+ LK ++ Q+ T+ E+ ++ ++ S E+
Sbjct: 343 --MTEEQHSLKSKIKQMTTD-LEIYNDLPALKSSGEK 376
>AY803272-1|AAW30454.1| 1492|Homo sapiens AKAP9-BRAF fusion protein
protein.
Length = 1492
Score = 53.6 bits (123), Expect = 2e-06
Identities = 92/391 (23%), Positives = 178/391 (45%), Gaps = 47/391 (12%)
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMV-VPEIIDSLTEVINTLTNGFESLEEVALEI 151
+L KL ED LE R NI+ ++ + + ID L N ++ E+++ +
Sbjct: 636 ELSKLKED----LEIEHRINIEKLKDNLGIHYKQQIDGLQ---NEMSQKIETMQFEKDNL 688
Query: 152 DLKKNSITKDNISIKTLLDKLI-TKNET---DINELRNSIKYLESVKSEYNTANEKLFE- 206
K+N + + +K L L+ +K+E INEL+ I+ L + E T +++ E
Sbjct: 689 ITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL 748
Query: 207 QLNNAV------DKQNCIQEEVDLLKIENQNLL-QXXXXXXXXXXXXXXXXXARDKFIAN 259
QL + +K+N +QE+ L+ EN L + R F+ +
Sbjct: 749 QLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDS 808
Query: 260 LEEMKTMLVEEKLSEIK-EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
++ V EK EI E++E+ KQ+ LNE++ R F + EKN +V
Sbjct: 809 IKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTF--SFAEKNF-------EV 859
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENN---SYKLIENMFNKVSQIASDFKISNQLSCELD 375
N +EL+E+ L + + L D++N YK N+ + + ++ +
Sbjct: 860 N--YQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 917
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKER 435
DE + T+ +L + ++ T T++ E + + L E ++++DL+EQ LK++
Sbjct: 918 DE-DKTFVAETLEMGEVVEKDT---TELMEKLEVTKREKL-ELSQRLSDLSEQ---LKQK 969
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
++ N+ E+++++ E+V+L ++
Sbjct: 970 HGEISFLNE----EVKSLKQEKEQVSLRCRE 996
Score = 51.2 bits (117), Expect = 9e-06
Identities = 72/307 (23%), Positives = 139/307 (45%), Gaps = 26/307 (8%)
Query: 173 ITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL 232
IT NE I + +I L + N+ EKL E+L ++++ +Q +++ L E
Sbjct: 481 ITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFS 540
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLV--EEKLSEIKEKDE----NFKQEI 286
+ K ++ +E++K +V E E++ K E N+K ++
Sbjct: 541 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 600
Query: 287 DMLNEK--LICDR-REFNETMQEK---NILLS---DLSKKVNKTERE----LEEKQEQL- 332
+ML ++ + DR E E E+ +L S +LSK E E +E+ ++ L
Sbjct: 601 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLG 660
Query: 333 THLMEQLNDTENNSYKLIENM-FNKVSQIASDFKISNQLS--CELDDESENT-YERISLT 388
H +Q++ +N + IE M F K + I ++ ++S +L N+ E ++L
Sbjct: 661 IHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ 720
Query: 389 LDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++++ I L + E T + + +L + + + E+ L+E+ +QLE EN L
Sbjct: 721 INELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSIL 780
Query: 447 LIEIQTV 453
E +T+
Sbjct: 781 KDEKKTL 787
Score = 45.2 bits (102), Expect = 6e-04
Identities = 56/335 (16%), Positives = 145/335 (43%), Gaps = 22/335 (6%)
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
LE + E+ K++ I + N ++ + T+ + E +IK + + ++ ++
Sbjct: 157 LEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQ 216
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNL-LQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ + + + + E+ L+I+ Q L A+ + + + ++
Sbjct: 217 ARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQ 276
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC-----DRREFN---ETMQEKNILLSDL 314
++ + L + ++K E+F +I L EK+ D++ N E +QEK ++ +L
Sbjct: 277 LEEQ--DHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 334
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ K+ + E++ E +++LT + L + + + + + N ++ + + Q S E+
Sbjct: 335 NTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEI 394
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII--- 431
+ T E L K + + T I + + + + L + + ++ ++ Q I+
Sbjct: 395 -KQLMGTVEE----LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMK 449
Query: 432 ---LKERLSQLETENKELLIEIQTVRGSNEEVTLN 463
+++ ++Q+E E++ S +T+N
Sbjct: 450 QELIRQHMAQMEEMKTRHKGEMENALRSYSNITVN 484
>AY422473-1|AAR13704.1| 1326|Homo sapiens myosin tail
domain-containing protein protein.
Length = 1326
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/193 (22%), Positives = 91/193 (47%), Gaps = 11/193 (5%)
Query: 257 IANLEEMKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
+A+LE +K E + + +EK E+F + +++L ++ ++ NE ++E+ ++ D
Sbjct: 326 VADLEIIKNEFKEVESAYEREKHNAQESFAK-LNLLEKEYFSKNKKLNEDIEEQKKVIID 384
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
LSK++ E+ E QE+L + + + EN ++ I F +S Q +
Sbjct: 385 LSKRLQYNEKSCSELQEELVMAKKH----QAFLVETCENNVKELESILDSFTVSGQWTSG 440
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
+ + + S+ L+++ +T ++ + + A ++ KQ D +NI K
Sbjct: 441 IHKDKDKP-PSFSVVLERLRRTLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNI--K 497
Query: 434 ERLSQLETENKEL 446
E +L NKEL
Sbjct: 498 ELQDKLADVNKEL 510
Score = 32.7 bits (71), Expect = 3.2
Identities = 84/411 (20%), Positives = 161/411 (39%), Gaps = 42/411 (10%)
Query: 123 VPEIIDSLTE--VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDI 180
V +I+ + TE + + L ++ LEI K N+ + S ++ + KL ++E +
Sbjct: 22 VKQILKNETELDITDNLRKKLHWAKKEKLEITTKHNA---ELASYESQIAKL--RSEVEK 76
Query: 181 NE-LRNSIKY-LESVKSEYNTANEKLFEQLNNA--VDKQNCIQE-EVDLLKIENQNLLQX 235
E LR S++Y L + E E+L A + ++ C Q E+ E + Q
Sbjct: 77 GEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQT 136
Query: 236 XXXXXXXX-XXXXXXXXARDKFIANLEEMKTMLVEEK------LSEIKEKDENFKQEID- 287
RD I N +L++EK L E EK + K E++
Sbjct: 137 SQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEMES 196
Query: 288 -----------MLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQL---T 333
+ E+ +RRE +QE++ + ++ KKV K E E + + L T
Sbjct: 197 HIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQT 256
Query: 334 HLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI-----SLT 388
+E E K E +V ++ + + E SE RI +L
Sbjct: 257 SELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQ 316
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA--DLTEQNIILKERLSQLETENKEL 446
++K + + +I + + + + +E +K A + N++ KE S+ + N+++
Sbjct: 317 VEKASQAEAVADLEIIKNEFKE-VESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDI 375
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKS 497
+ + + ++ + N K S + +E + V E +S
Sbjct: 376 EEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELES 426
Score = 31.9 bits (69), Expect = 5.6
Identities = 22/95 (23%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Query: 254 DKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL---ICDRREFNETMQEKNIL 310
+KF + EE+ L+ E+ +++ ++ Q++ LN KL + + N+T+ E
Sbjct: 1033 EKFESACEELNNALLREEQAQMLLNEQ--AQQLQELNYKLELHSSEEADKNQTLGEAVKS 1090
Query: 311 LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN 345
LS+ ++ + ++ L + LT L + E N
Sbjct: 1091 LSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEEN 1125
>AL662788-1|CAI95333.1| 1326|Homo sapiens chromosome 9 open reading
frame 93 protein.
Length = 1326
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/193 (22%), Positives = 91/193 (47%), Gaps = 11/193 (5%)
Query: 257 IANLEEMKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
+A+LE +K E + + +EK E+F + +++L ++ ++ NE ++E+ ++ D
Sbjct: 326 VADLEIIKNEFKEVESAYEREKHNAQESFAK-LNLLEKEYFSKNKKLNEDIEEQKKVIID 384
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
LSK++ E+ E QE+L + + + EN ++ I F +S Q +
Sbjct: 385 LSKRLQYNEKSCSELQEELVMAKKH----QAFLVETCENNVKELESILDSFTVSGQWTSG 440
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
+ + + S+ L+++ +T ++ + + A ++ KQ D +NI K
Sbjct: 441 IHKDKDKP-PSFSVVLERLRRTLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNI--K 497
Query: 434 ERLSQLETENKEL 446
E +L NKEL
Sbjct: 498 ELQDKLADVNKEL 510
Score = 32.7 bits (71), Expect = 3.2
Identities = 84/411 (20%), Positives = 161/411 (39%), Gaps = 42/411 (10%)
Query: 123 VPEIIDSLTE--VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDI 180
V +I+ + TE + + L ++ LEI K N+ + S ++ + KL ++E +
Sbjct: 22 VKQILKNETELDITDNLRKKLHWAKKEKLEITTKHNA---ELASYESQIAKL--RSEVEK 76
Query: 181 NE-LRNSIKY-LESVKSEYNTANEKLFEQLNNA--VDKQNCIQE-EVDLLKIENQNLLQX 235
E LR S++Y L + E E+L A + ++ C Q E+ E + Q
Sbjct: 77 GEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQT 136
Query: 236 XXXXXXXX-XXXXXXXXARDKFIANLEEMKTMLVEEK------LSEIKEKDENFKQEID- 287
RD I N +L++EK L E EK + K E++
Sbjct: 137 SQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEMES 196
Query: 288 -----------MLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQL---T 333
+ E+ +RRE +QE++ + ++ KKV K E E + + L T
Sbjct: 197 HIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQT 256
Query: 334 HLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI-----SLT 388
+E E K E +V ++ + + E SE RI +L
Sbjct: 257 SELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQ 316
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA--DLTEQNIILKERLSQLETENKEL 446
++K + + +I + + + + +E +K A + N++ KE S+ + N+++
Sbjct: 317 VEKASQAEAVADLEIIKNEFKE-VESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDI 375
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKS 497
+ + + ++ + N K S + +E + V E +S
Sbjct: 376 EEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELES 426
Score = 31.9 bits (69), Expect = 5.6
Identities = 22/95 (23%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Query: 254 DKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL---ICDRREFNETMQEKNIL 310
+KF + EE+ L+ E+ +++ ++ Q++ LN KL + + N+T+ E
Sbjct: 1033 EKFESACEELNNALLREEQAQMLLNEQ--AQQLQELNYKLELHSSEEADKNQTLGEAVKS 1090
Query: 311 LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN 345
LS+ ++ + ++ L + LT L + E N
Sbjct: 1091 LSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEEN 1125
>AL592153-1|CAI95316.1| 1326|Homo sapiens chromosome 9 open reading
frame 93 protein.
Length = 1326
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/193 (22%), Positives = 91/193 (47%), Gaps = 11/193 (5%)
Query: 257 IANLEEMKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
+A+LE +K E + + +EK E+F + +++L ++ ++ NE ++E+ ++ D
Sbjct: 326 VADLEIIKNEFKEVESAYEREKHNAQESFAK-LNLLEKEYFSKNKKLNEDIEEQKKVIID 384
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
LSK++ E+ E QE+L + + + EN ++ I F +S Q +
Sbjct: 385 LSKRLQYNEKSCSELQEELVMAKKH----QAFLVETCENNVKELESILDSFTVSGQWTSG 440
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
+ + + S+ L+++ +T ++ + + A ++ KQ D +NI K
Sbjct: 441 IHKDKDKP-PSFSVVLERLRRTLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNI--K 497
Query: 434 ERLSQLETENKEL 446
E +L NKEL
Sbjct: 498 ELQDKLADVNKEL 510
Score = 32.7 bits (71), Expect = 3.2
Identities = 84/411 (20%), Positives = 161/411 (39%), Gaps = 42/411 (10%)
Query: 123 VPEIIDSLTE--VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDI 180
V +I+ + TE + + L ++ LEI K N+ + S ++ + KL ++E +
Sbjct: 22 VKQILKNETELDITDNLRKKLHWAKKEKLEITTKHNA---ELASYESQIAKL--RSEVEK 76
Query: 181 NE-LRNSIKY-LESVKSEYNTANEKLFEQLNNA--VDKQNCIQE-EVDLLKIENQNLLQX 235
E LR S++Y L + E E+L A + ++ C Q E+ E + Q
Sbjct: 77 GEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQT 136
Query: 236 XXXXXXXX-XXXXXXXXARDKFIANLEEMKTMLVEEK------LSEIKEKDENFKQEID- 287
RD I N +L++EK L E EK + K E++
Sbjct: 137 SQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEMES 196
Query: 288 -----------MLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQL---T 333
+ E+ +RRE +QE++ + ++ KKV K E E + + L T
Sbjct: 197 HIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQT 256
Query: 334 HLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI-----SLT 388
+E E K E +V ++ + + E SE RI +L
Sbjct: 257 SELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQ 316
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA--DLTEQNIILKERLSQLETENKEL 446
++K + + +I + + + + +E +K A + N++ KE S+ + N+++
Sbjct: 317 VEKASQAEAVADLEIIKNEFKE-VESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDI 375
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKS 497
+ + + ++ + N K S + +E + V E +S
Sbjct: 376 EEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELES 426
Score = 31.9 bits (69), Expect = 5.6
Identities = 22/95 (23%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Query: 254 DKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL---ICDRREFNETMQEKNIL 310
+KF + EE+ L+ E+ +++ ++ Q++ LN KL + + N+T+ E
Sbjct: 1033 EKFESACEELNNALLREEQAQMLLNEQ--AQQLQELNYKLELHSSEEADKNQTLGEAVKS 1090
Query: 311 LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN 345
LS+ ++ + ++ L + LT L + E N
Sbjct: 1091 LSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEEN 1125
>AL359877-3|CAI94977.1| 1326|Homo sapiens chromosome 9 open reading
frame 93 protein.
Length = 1326
Score = 53.6 bits (123), Expect = 2e-06
Identities = 44/193 (22%), Positives = 91/193 (47%), Gaps = 11/193 (5%)
Query: 257 IANLEEMKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
+A+LE +K E + + +EK E+F + +++L ++ ++ NE ++E+ ++ D
Sbjct: 326 VADLEIIKNEFKEVESAYEREKHNAQESFAK-LNLLEKEYFSKNKKLNEDIEEQKKVIID 384
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
LSK++ E+ E QE+L + + + EN ++ I F +S Q +
Sbjct: 385 LSKRLQYNEKSCSELQEELVMAKKH----QAFLVETCENNVKELESILDSFTVSGQWTSG 440
Query: 374 LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
+ + + S+ L+++ +T ++ + + A ++ KQ D +NI K
Sbjct: 441 IHKDKDKP-PSFSVVLERLRRTLTDYQNKLEDASNEEKACNELDSTKQKIDSHTKNI--K 497
Query: 434 ERLSQLETENKEL 446
E +L NKEL
Sbjct: 498 ELQDKLADVNKEL 510
Score = 32.7 bits (71), Expect = 3.2
Identities = 84/411 (20%), Positives = 161/411 (39%), Gaps = 42/411 (10%)
Query: 123 VPEIIDSLTE--VINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDI 180
V +I+ + TE + + L ++ LEI K N+ + S ++ + KL ++E +
Sbjct: 22 VKQILKNETELDITDNLRKKLHWAKKEKLEITTKHNA---ELASYESQIAKL--RSEVEK 76
Query: 181 NE-LRNSIKY-LESVKSEYNTANEKLFEQLNNA--VDKQNCIQE-EVDLLKIENQNLLQX 235
E LR S++Y L + E E+L A + ++ C Q E+ E + Q
Sbjct: 77 GEALRQSLEYDLAVARKEAGLGRRAAEERLAEAHRIQEKLCAQNSELQAKTNETEKAFQT 136
Query: 236 XXXXXXXX-XXXXXXXXARDKFIANLEEMKTMLVEEK------LSEIKEKDENFKQEID- 287
RD I N +L++EK L E EK + K E++
Sbjct: 137 SQQKWKEECRRFEHDLEERDNMIQNCNREYDLLMKEKSRLEKTLQEALEKHQREKNEMES 196
Query: 288 -----------MLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQL---T 333
+ E+ +RRE +QE++ + ++ KKV K E E + + L T
Sbjct: 197 HIRETALEEFRLQEEQWEAERRELQFIVQEQDTAVQNMHKKVEKLETEHMDCSDLLRRQT 256
Query: 334 HLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI-----SLT 388
+E E K E +V ++ + + E SE RI +L
Sbjct: 257 SELEFSTQREERLRKEFEATTLRVRKLEENIEAERAAHLESKFNSEIIQLRIRDLEGALQ 316
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA--DLTEQNIILKERLSQLETENKEL 446
++K + + +I + + + + +E +K A + N++ KE S+ + N+++
Sbjct: 317 VEKASQAEAVADLEIIKNEFKE-VESAYEREKHNAQESFAKLNLLEKEYFSKNKKLNEDI 375
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKS 497
+ + + ++ + N K S + +E + V E +S
Sbjct: 376 EEQKKVIIDLSKRLQYNEKSCSELQEELVMAKKHQAFLVETCENNVKELES 426
Score = 31.9 bits (69), Expect = 5.6
Identities = 22/95 (23%), Positives = 46/95 (48%), Gaps = 5/95 (5%)
Query: 254 DKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL---ICDRREFNETMQEKNIL 310
+KF + EE+ L+ E+ +++ ++ Q++ LN KL + + N+T+ E
Sbjct: 1033 EKFESACEELNNALLREEQAQMLLNEQ--AQQLQELNYKLELHSSEEADKNQTLGEAVKS 1090
Query: 311 LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN 345
LS+ ++ + ++ L + LT L + E N
Sbjct: 1091 LSEAKMELRRKDQSLRQLNRHLTQLEQDKRRLEEN 1125
>AJ010770-1|CAA09361.1| 3911|Homo sapiens Hyperion protein protein.
Length = 3911
Score = 53.6 bits (123), Expect = 2e-06
Identities = 92/391 (23%), Positives = 178/391 (45%), Gaps = 47/391 (12%)
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMV-VPEIIDSLTEVINTLTNGFESLEEVALEI 151
+L KL ED LE R NI+ ++ + + ID L N ++ E+++ +
Sbjct: 648 ELSKLKED----LEIEHRINIEKLKDNLGIHYKQQIDGLQ---NEMSQKIETMQFEKDNL 700
Query: 152 DLKKNSITKDNISIKTLLDKLI-TKNET---DINELRNSIKYLESVKSEYNTANEKLFE- 206
K+N + + +K L L+ +K+E INEL+ I+ L + E T +++ E
Sbjct: 701 ITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL 760
Query: 207 QLNNAV------DKQNCIQEEVDLLKIENQNLL-QXXXXXXXXXXXXXXXXXARDKFIAN 259
QL + +K+N +QE+ L+ EN L + R F+ +
Sbjct: 761 QLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDS 820
Query: 260 LEEMKTMLVEEKLSEIK-EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
++ V EK EI E++E+ KQ+ LNE++ R F + EKN +V
Sbjct: 821 IKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTF--SFAEKNF-------EV 871
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENN---SYKLIENMFNKVSQIASDFKISNQLSCELD 375
N +EL+E+ L + + L D++N YK N+ + + ++ +
Sbjct: 872 N--YQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 929
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKER 435
DE + T+ +L + ++ T T++ E + + L E ++++DL+EQ LK++
Sbjct: 930 DE-DKTFVAETLEMGEVVEKDT---TELMEKLEVTKREKL-ELSQRLSDLSEQ---LKQK 981
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
++ N+ E+++++ E+V+L ++
Sbjct: 982 HGEISFLNE----EVKSLKQEKEQVSLRCRE 1008
Score = 51.2 bits (117), Expect = 9e-06
Identities = 72/307 (23%), Positives = 139/307 (45%), Gaps = 26/307 (8%)
Query: 173 ITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL 232
IT NE I + +I L + N+ EKL E+L ++++ +Q +++ L E
Sbjct: 493 ITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFS 552
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLV--EEKLSEIKEKDE----NFKQEI 286
+ K ++ +E++K +V E E++ K E N+K ++
Sbjct: 553 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 612
Query: 287 DMLNEK--LICDR-REFNETMQEK---NILLS---DLSKKVNKTERE----LEEKQEQL- 332
+ML ++ + DR E E E+ +L S +LSK E E +E+ ++ L
Sbjct: 613 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLG 672
Query: 333 THLMEQLNDTENNSYKLIENM-FNKVSQIASDFKISNQLS--CELDDESENT-YERISLT 388
H +Q++ +N + IE M F K + I ++ ++S +L N+ E ++L
Sbjct: 673 IHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ 732
Query: 389 LDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++++ I L + E T + + +L + + + E+ L+E+ +QLE EN L
Sbjct: 733 INELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSIL 792
Query: 447 LIEIQTV 453
E +T+
Sbjct: 793 KDEKKTL 799
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/190 (19%), Positives = 95/190 (50%), Gaps = 15/190 (7%)
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQE 330
+L E++++++ FK +++ L + + + Q++++L ++ + + E E+++ E
Sbjct: 2255 RLQELEQENKLFKDDMEKLG---LAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNE 2311
Query: 331 QLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK-ISNQLSCELDDESENTYERISLTL 389
Q+T L +QL T +N K+IE + + + + + + C + E E+++ +
Sbjct: 2312 QVTKLQQQLKITTDN--KVIEEKNELIRDLETQIECLMSDQEC-VKRNREEEIEQLNEVI 2368
Query: 390 DKITNHITYL--NTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
+K+ + + T +N ++ A L K Q+ + + + L++ Q+ET N+E+
Sbjct: 2369 EKLQQELANIGQKTSMNAHSLSEEADSL---KHQLDVVIAEKLALEQ---QVETANEEMT 2422
Query: 448 IEIQTVRGSN 457
++ +N
Sbjct: 2423 FMKNVLKETN 2432
Score = 45.2 bits (102), Expect = 6e-04
Identities = 56/335 (16%), Positives = 145/335 (43%), Gaps = 22/335 (6%)
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
LE + E+ K++ I + N ++ + T+ + E +IK + + ++ ++
Sbjct: 169 LEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQ 228
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNL-LQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ + + + + E+ L+I+ Q L A+ + + + ++
Sbjct: 229 ARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQ 288
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC-----DRREFN---ETMQEKNILLSDL 314
++ + L + ++K E+F +I L EK+ D++ N E +QEK ++ +L
Sbjct: 289 LEEQ--DHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 346
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ K+ + E++ E +++LT + L + + + + + N ++ + + Q S E+
Sbjct: 347 NTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEI 406
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII--- 431
+ T E L K + + T I + + + + L + + ++ ++ Q I+
Sbjct: 407 -KQLMGTVEE----LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMK 461
Query: 432 ---LKERLSQLETENKELLIEIQTVRGSNEEVTLN 463
+++ ++Q+E E++ S +T+N
Sbjct: 462 QELIRQHMAQMEEMKTRHKGEMENALRSYSNITVN 496
Score = 40.3 bits (90), Expect = 0.016
Identities = 50/214 (23%), Positives = 94/214 (43%), Gaps = 17/214 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQE---KNILLSDLSKK 317
+E + +EE+L + +E+ EN +E+ L+ +L ++E +QE +N L D +K
Sbjct: 2213 KEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEK 2272
Query: 318 VNKTERELEEKQEQLTHLM----EQLNDTENNSYKLIENMFNKVSQ---IASDFKI---S 367
+ +E + Q H++ Q+ + + K+ Q I +D K+
Sbjct: 2273 LGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEK 2332
Query: 368 NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE 427
N+L +L+ + E I LN I + Q+ + A + + L+E
Sbjct: 2333 NELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ-ELANIGQKTSMNAHSLSE 2391
Query: 428 QNIILKERLSQLETENKELLIEIQTVRGSNEEVT 461
+ LK +L + E +L +E Q V +NEE+T
Sbjct: 2392 EADSLKHQLDVVIAE--KLALE-QQVETANEEMT 2422
Score = 36.3 bits (80), Expect = 0.26
Identities = 75/345 (21%), Positives = 146/345 (42%), Gaps = 35/345 (10%)
Query: 127 IDSLTEVINTLTN-GFE-SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR 184
+ SL + + T+T+ G E S+ +V + + +D +S + + +K E I +
Sbjct: 1028 VSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHL 1087
Query: 185 NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
S+ S+++ + N+KL ++LN +QN ++ L++E Q +
Sbjct: 1088 PSVTKESSLRATQPSENDKLQKELNVLKSEQNDLR-----LQMEAQRICLSLVYSTHVDQ 1142
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
+DK + +L+E EEK+ E+ Q+I L E +E +
Sbjct: 1143 VREYMENEKDKALCSLKEELIFAQEEKIKEL--------QKIHQL-ELQTMKTQETGDEG 1193
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+ ++L+ L K V+ EE L L L + + K N +K + + D+
Sbjct: 1194 KPLHLLIGKLQKAVS------EECSYFLQTLCSVLGEYYTPALKCEVNAEDK--ENSGDY 1245
Query: 365 KISNQLSCELDD---ESENTYERISLTLDKIT---NHITYLNTQINET--QKNDNAQLLW 416
IS EL D E ++ E + L+K+T N + L T++++ Q+ D +L +
Sbjct: 1246 -ISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEF 1304
Query: 417 EAKKQIADLTEQNIILKE--RLSQLETENKELLIEIQTVRGSNEE 459
+ + TE I + L ++ +K L +Q + + E
Sbjct: 1305 GEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLE 1349
Score = 36.3 bits (80), Expect = 0.26
Identities = 41/161 (25%), Positives = 82/161 (50%), Gaps = 11/161 (6%)
Query: 260 LEEMKTMLVEEKLSEIKEK-DENFKQEIDMLN--EKLICDRREFNETMQEKNILLSDLSK 316
L+E++ L EEK S I E +E K ++D L +++ DR+ +T+Q + ++ K
Sbjct: 3349 LKELQKQL-EEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQK 3407
Query: 317 KVNKTERELEEKQEQLTHLMEQLN--DTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
K+++ + ++E+ Q QL +Q+ D E + I F K + + S ++ +
Sbjct: 3408 KMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQN 3467
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL 415
+E T+ SLT D+ N + + ET++++ A+L+
Sbjct: 3468 LNE-PTTW---SLTSDRTRNWVLQQKIE-GETKESNYAKLI 3503
Score = 33.5 bits (73), Expect = 1.8
Identities = 16/82 (19%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
EE + + + +++ +++ D N K ++ L + ++ + E +QE L+S L +++ +
Sbjct: 1312 EETEFLSIHSQMTNLEDIDVNHKSKLSSLQD---LEKTKLEEQVQELESLISSLQQQLKE 1368
Query: 321 TERELEEKQEQLTHLMEQLNDT 342
TE+ E + L ++ ++++
Sbjct: 1369 TEQNYEAEIHCLQKRLQAVSES 1390
Score = 33.1 bits (72), Expect = 2.4
Identities = 56/270 (20%), Positives = 116/270 (42%), Gaps = 24/270 (8%)
Query: 210 NAVDKQNCIQEEVDLLKIENQ---NLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+AV NC+++ + +E Q LQ + I E ++
Sbjct: 3060 DAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESE 3119
Query: 267 LVEEKLSE--IKEKDENF-KQEIDMLNEKLICDRR-EFNETMQEKNILLSDLSKKVNKTE 322
++L E I++K + ++++ + K DR E E + + +++++L ++ +T+
Sbjct: 3120 KPSQELLEYNIQQKQSQMLEMQVELSSMK---DRATELQEQLSSEKMVVAELKSELAQTK 3176
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
ELE + +++L + + +AS+ K S +L L+ E
Sbjct: 3177 LELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKA--- 3233
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQL--LWEAKKQIADLTEQNI-----ILKER 435
++ + ++ + L + E+QK N QL L E +KQ+ + ++Q I + +
Sbjct: 3234 -KLGRSEERDKEELEDLKFSL-ESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQ 3291
Query: 436 LSQLETENKEL--LIEIQTVRGSNEEVTLN 463
LS+ + N EL L+E + VR TL+
Sbjct: 3292 LSEEQGRNLELQVLLESEKVRIREMSSTLD 3321
Score = 32.7 bits (71), Expect = 3.2
Identities = 73/378 (19%), Positives = 162/378 (42%), Gaps = 31/378 (8%)
Query: 80 LTEKLTI---AETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINT 136
+ EKL + AE +DL+K + ++E I++ + ++ +
Sbjct: 2014 MKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQ 2073
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
L + L+E A++ + +++ ++ ++ L + ++ R + +K +
Sbjct: 2074 LEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEK 2133
Query: 197 YNTANEKLF--EQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ +E L EQL + ++N EE++ L+ + L Q
Sbjct: 2134 TDKCSELLLSKEQLQRDIQERN---EEIEKLEFRVRELEQALLVSADTFQKVEDR----- 2185
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF---NETMQEKNILL 311
K +E + +E +L ++ + ++EI L E+L R E NE +Q+ ++ L
Sbjct: 2186 KHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQL 2245
Query: 312 SDLSKKVNKTE-RELEEKQEQLTHLMEQLN----DTENNSYKLIENMFNKVSQIASDFKI 366
++ KK + T +ELE++ + ME+L +++ S + +F K +QI + ++
Sbjct: 2246 -EIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV 2304
Query: 367 SNQLSCELDDESENTYERISLTLD-KITNH----ITYLNTQINETQKNDNAQLLWEAKKQ 421
+L+++ +++ +T D K+ I L TQI E +D + +++
Sbjct: 2305 EID---QLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQI-ECLMSDQECVKRNREEE 2360
Query: 422 IADLTEQNIILKERLSQL 439
I L E L++ L+ +
Sbjct: 2361 IEQLNEVIEKLQQELANI 2378
Score = 32.3 bits (70), Expect = 4.2
Identities = 78/413 (18%), Positives = 174/413 (42%), Gaps = 29/413 (7%)
Query: 123 VPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINE 182
V +++++++E + L + + E+ E +K T+ + L ++L ++ +
Sbjct: 1866 VEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAR-EQ 1924
Query: 183 LRNSIKYLESVKSEY---NTANEKLFEQLNNAVDKQN----CIQEEVDLLKIENQNLLQX 235
L + E V Y T E+ ++ + +D+ C + L+ E Q + +
Sbjct: 1925 LAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEE 1984
Query: 236 XXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC 295
++ + L+E + L++EKL E++ + E + ++ + L
Sbjct: 1985 RELLSRQKEAMKAEAGPVEQQL--LQETEK-LMKEKL-EVQCQAEKVRDDLQKQVKALEI 2040
Query: 296 DRRE----FNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL---MEQLNDTENNSYK 348
D E F E QEKN L DL ++ E++LE+ ++ L E D +
Sbjct: 2041 DVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQ 2100
Query: 349 LIENMFNKVS--QIASDFKIS--NQLSCELDDESENTYERISLTLDKITNHITYLNTQIN 404
+E V Q S+ + QL+ L ++++ E + L+ +++ I N +I
Sbjct: 2101 KLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSE-LLLSKEQLQRDIQERNEEIE 2159
Query: 405 ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNL 464
+ + + L +A AD T Q + ++ +E + EL +E+Q ++ + +
Sbjct: 2160 KLE--FRVRELEQALLVSAD-TFQKVEDRKHFGAVEAK-PELSLEVQ-LQAERDAIDRKE 2214
Query: 465 KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
K+ + N+ E+++ M+ + Q ++ +++ ++E KL K
Sbjct: 2215 KEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFK 2267
>AF083037-1|AAD22767.1| 3595|Homo sapiens A-kinase anchoring protein
AKAP350 protein.
Length = 3595
Score = 53.6 bits (123), Expect = 2e-06
Identities = 92/391 (23%), Positives = 178/391 (45%), Gaps = 47/391 (12%)
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMV-VPEIIDSLTEVINTLTNGFESLEEVALEI 151
+L KL ED LE R NI+ ++ + + ID L N ++ E+++ +
Sbjct: 326 ELSKLKED----LEIEHRINIEKLKDNLGIHYKQQIDGLQ---NEMSQKIETMQFEKDNL 378
Query: 152 DLKKNSITKDNISIKTLLDKLI-TKNET---DINELRNSIKYLESVKSEYNTANEKLFE- 206
K+N + + +K L L+ +K+E INEL+ I+ L + E T +++ E
Sbjct: 379 ITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL 438
Query: 207 QLNNAV------DKQNCIQEEVDLLKIENQNLL-QXXXXXXXXXXXXXXXXXARDKFIAN 259
QL + +K+N +QE+ L+ EN L + R F+ +
Sbjct: 439 QLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDS 498
Query: 260 LEEMKTMLVEEKLSEIK-EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
++ V EK EI E++E+ KQ+ LNE++ R F + EKN +V
Sbjct: 499 IKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTF--SFAEKNF-------EV 549
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENN---SYKLIENMFNKVSQIASDFKISNQLSCELD 375
N +EL+E+ L + + L D++N YK N+ + + ++ +
Sbjct: 550 N--YQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 607
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKER 435
DE + T+ +L + ++ T T++ E + + L E ++++DL+EQ LK++
Sbjct: 608 DE-DKTFVAETLEMGEVVEKDT---TELMEKLEVTKREKL-ELSQRLSDLSEQ---LKQK 659
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
++ N+ E+++++ E+V+L ++
Sbjct: 660 HGEISFLNE----EVKSLKQEKEQVSLRCRE 686
Score = 51.2 bits (117), Expect = 9e-06
Identities = 72/307 (23%), Positives = 139/307 (45%), Gaps = 26/307 (8%)
Query: 173 ITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL 232
IT NE I + +I L + N+ EKL E+L ++++ +Q +++ L E
Sbjct: 171 ITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFS 230
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLV--EEKLSEIKEKDE----NFKQEI 286
+ K ++ +E++K +V E E++ K E N+K ++
Sbjct: 231 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 290
Query: 287 DMLNEK--LICDR-REFNETMQEK---NILLS---DLSKKVNKTERE----LEEKQEQL- 332
+ML ++ + DR E E E+ +L S +LSK E E +E+ ++ L
Sbjct: 291 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLG 350
Query: 333 THLMEQLNDTENNSYKLIENM-FNKVSQIASDFKISNQLS--CELDDESENT-YERISLT 388
H +Q++ +N + IE M F K + I ++ ++S +L N+ E ++L
Sbjct: 351 IHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ 410
Query: 389 LDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++++ I L + E T + + +L + + + E+ L+E+ +QLE EN L
Sbjct: 411 INELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSIL 470
Query: 447 LIEIQTV 453
E +T+
Sbjct: 471 KDEKKTL 477
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/190 (19%), Positives = 95/190 (50%), Gaps = 15/190 (7%)
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQE 330
+L E++++++ FK +++ L + + + Q++++L ++ + + E E+++ E
Sbjct: 1931 RLQELEQENKLFKDDMEKLG---LAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNE 1987
Query: 331 QLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK-ISNQLSCELDDESENTYERISLTL 389
Q+T L +QL T +N K+IE + + + + + + C + E E+++ +
Sbjct: 1988 QVTKLQQQLKITTDN--KVIEEKNELIRDLETQIECLMSDQEC-VKRNREEEIEQLNEVI 2044
Query: 390 DKITNHITYL--NTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
+K+ + + T +N ++ A L K Q+ + + + L++ Q+ET N+E+
Sbjct: 2045 EKLQQELANIGQKTSMNAHSLSEEADSL---KHQLDVVIAEKLALEQ---QVETANEEMT 2098
Query: 448 IEIQTVRGSN 457
++ +N
Sbjct: 2099 FMKNVLKETN 2108
Score = 40.3 bits (90), Expect = 0.016
Identities = 50/214 (23%), Positives = 94/214 (43%), Gaps = 17/214 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQE---KNILLSDLSKK 317
+E + +EE+L + +E+ EN +E+ L+ +L ++E +QE +N L D +K
Sbjct: 1889 KEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEK 1948
Query: 318 VNKTERELEEKQEQLTHLM----EQLNDTENNSYKLIENMFNKVSQ---IASDFKI---S 367
+ +E + Q H++ Q+ + + K+ Q I +D K+
Sbjct: 1949 LGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEK 2008
Query: 368 NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE 427
N+L +L+ + E I LN I + Q+ + A + + L+E
Sbjct: 2009 NELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ-ELANIGQKTSMNAHSLSE 2067
Query: 428 QNIILKERLSQLETENKELLIEIQTVRGSNEEVT 461
+ LK +L + E +L +E Q V +NEE+T
Sbjct: 2068 EADSLKHQLDVVIAE--KLALE-QQVETANEEMT 2098
Score = 36.3 bits (80), Expect = 0.26
Identities = 75/345 (21%), Positives = 146/345 (42%), Gaps = 35/345 (10%)
Query: 127 IDSLTEVINTLTN-GFE-SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR 184
+ SL + + T+T+ G E S+ +V + + +D +S + + +K E I +
Sbjct: 706 VSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHL 765
Query: 185 NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
S+ S+++ + N+KL ++LN +QN ++ L++E Q +
Sbjct: 766 PSVTKESSLRATQPSENDKLQKELNVLKSEQNDLR-----LQMEAQRICLSLVYSTHVDQ 820
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
+DK + +L+E EEK+ E+ Q+I L E +E +
Sbjct: 821 VREYMENEKDKALCSLKEELIFAQEEKIKEL--------QKIHQL-ELQTMKTQETGDEG 871
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+ ++L+ L K V+ EE L L L + + K N +K + + D+
Sbjct: 872 KPLHLLIGKLQKAVS------EECSYFLQTLCSVLGEYYTPALKCEVNAEDK--ENSGDY 923
Query: 365 KISNQLSCELDD---ESENTYERISLTLDKIT---NHITYLNTQINET--QKNDNAQLLW 416
IS EL D E ++ E + L+K+T N + L T++++ Q+ D +L +
Sbjct: 924 -ISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEF 982
Query: 417 EAKKQIADLTEQNIILKE--RLSQLETENKELLIEIQTVRGSNEE 459
+ + TE I + L ++ +K L +Q + + E
Sbjct: 983 GEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLE 1027
Score = 36.3 bits (80), Expect = 0.26
Identities = 41/161 (25%), Positives = 82/161 (50%), Gaps = 11/161 (6%)
Query: 260 LEEMKTMLVEEKLSEIKEK-DENFKQEIDMLN--EKLICDRREFNETMQEKNILLSDLSK 316
L+E++ L EEK S I E +E K ++D L +++ DR+ +T+Q + ++ K
Sbjct: 3033 LKELQKQL-EEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQK 3091
Query: 317 KVNKTERELEEKQEQLTHLMEQLN--DTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
K+++ + ++E+ Q QL +Q+ D E + I F K + + S ++ +
Sbjct: 3092 KMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQN 3151
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL 415
+E T+ SLT D+ N + + ET++++ A+L+
Sbjct: 3152 LNE-PTTW---SLTSDRTRNWVLQQKIE-GETKESNYAKLI 3187
Score = 33.5 bits (73), Expect = 1.8
Identities = 16/82 (19%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
EE + + + +++ +++ D N K ++ L + ++ + E +QE L+S L +++ +
Sbjct: 990 EETEFLSIHSQMTNLEDIDVNHKSKLSSLQD---LEKTKLEEQVQELESLISSLQQQLKE 1046
Query: 321 TERELEEKQEQLTHLMEQLNDT 342
TE+ E + L ++ ++++
Sbjct: 1047 TEQNYEAEIHCLQKRLQAVSES 1068
Score = 33.1 bits (72), Expect = 2.4
Identities = 73/378 (19%), Positives = 162/378 (42%), Gaps = 31/378 (8%)
Query: 80 LTEKLTI---AETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINT 136
+ EKL + AE +DL+K + ++E I++ + ++ +
Sbjct: 1690 MKEKLEVQCQAEKDRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQ 1749
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
L + L+E A++ + +++ ++ ++ L + ++ R + +K +
Sbjct: 1750 LEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEK 1809
Query: 197 YNTANEKLF--EQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ +E L EQL + ++N EE++ L+ + L Q
Sbjct: 1810 TDKCSELLLSKEQLQRDIQERN---EEIEKLEFRVRELEQALLVSADTFQKVEDR----- 1861
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF---NETMQEKNILL 311
K +E + +E +L ++ + ++EI L E+L R E NE +Q+ ++ L
Sbjct: 1862 KHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQL 1921
Query: 312 SDLSKKVNKTE-RELEEKQEQLTHLMEQLN----DTENNSYKLIENMFNKVSQIASDFKI 366
++ KK + T +ELE++ + ME+L +++ S + +F K +QI + ++
Sbjct: 1922 -EIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV 1980
Query: 367 SNQLSCELDDESENTYERISLTLD-KITNH----ITYLNTQINETQKNDNAQLLWEAKKQ 421
+L+++ +++ +T D K+ I L TQI E +D + +++
Sbjct: 1981 EID---QLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQI-ECLMSDQECVKRNREEE 2036
Query: 422 IADLTEQNIILKERLSQL 439
I L E L++ L+ +
Sbjct: 2037 IEQLNEVIEKLQQELANI 2054
Score = 33.1 bits (72), Expect = 2.4
Identities = 56/270 (20%), Positives = 116/270 (42%), Gaps = 24/270 (8%)
Query: 210 NAVDKQNCIQEEVDLLKIENQ---NLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+AV NC+++ + +E Q LQ + I E ++
Sbjct: 2744 DAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESE 2803
Query: 267 LVEEKLSE--IKEKDENF-KQEIDMLNEKLICDRR-EFNETMQEKNILLSDLSKKVNKTE 322
++L E I++K + ++++ + K DR E E + + +++++L ++ +T+
Sbjct: 2804 KPSQELLEYNIQQKQSQMLEMQVELSSMK---DRATELQEQLSSEKMVVAELKSELAQTK 2860
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
ELE + +++L + + +AS+ K S +L L+ E
Sbjct: 2861 LELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKA--- 2917
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQL--LWEAKKQIADLTEQNI-----ILKER 435
++ + ++ + L + E+QK N QL L E +KQ+ + ++Q I + +
Sbjct: 2918 -KLGRSEERDKEELEDLKFSL-ESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQ 2975
Query: 436 LSQLETENKEL--LIEIQTVRGSNEEVTLN 463
LS+ + N EL L+E + VR TL+
Sbjct: 2976 LSEEQGRNLELQVLLESEKVRIREMSSTLD 3005
Score = 32.7 bits (71), Expect = 3.2
Identities = 74/410 (18%), Positives = 167/410 (40%), Gaps = 23/410 (5%)
Query: 123 VPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINE 182
V +++++++E + L + + E+ E +K T+ + L ++L ++ +
Sbjct: 1542 VEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAR-EQ 1600
Query: 183 LRNSIKYLESVKSEY---NTANEKLFEQLNNAVDKQN----CIQEEVDLLKIENQNLLQX 235
L + E V Y T E+ ++ + +D+ C + L+ E Q + +
Sbjct: 1601 LAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEE 1660
Query: 236 XXXXXXXXXXXXXXXX-ARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLI 294
+ + E++ +E + K++D+ KQ + L +
Sbjct: 1661 RELLSRQKEAMKAEAGPVEQQLLQETEKLMKEKLEVQCQAEKDRDDLQKQ-VKALEIDVE 1719
Query: 295 CDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL---MEQLNDTENNSYKLIE 351
F E QEKN L DL ++ E++LE+ ++ L E D + +E
Sbjct: 1720 EQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQKLE 1779
Query: 352 NMFNKVS--QIASDFKIS--NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQ 407
V Q S+ + QL+ L ++++ E + L+ +++ I N +I + +
Sbjct: 1780 QQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSE-LLLSKEQLQRDIQERNEEIEKLE 1838
Query: 408 KNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS 467
+ L +A AD T Q + ++ +E + EL +E+Q ++ + + K+
Sbjct: 1839 --FRVRELEQALLVSAD-TFQKVEDRKHFGAVEAK-PELSLEVQ-LQAERDAIDRKEKEI 1893
Query: 468 STXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+ N+ E+++ M+ + Q ++ +++ ++E KL K
Sbjct: 1894 TNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFK 1943
Score = 31.9 bits (69), Expect = 5.6
Identities = 30/119 (25%), Positives = 59/119 (49%), Gaps = 12/119 (10%)
Query: 260 LEEMKTMLVEE--KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+EE+ T ++EE K E+K+K + + L E+++ +E KN+ L + K
Sbjct: 21 IEELNTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEI------KNMKLELTNSK 74
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
+ ER+ E+ +QL +E+L + + ++ ++ Q + K+ QL ELD+
Sbjct: 75 --QKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQ-ETQRKL-EQLRAELDE 129
>AC000066-1|AAC60380.1| 1620|Homo sapiens yotiao protein.
Length = 1620
Score = 53.6 bits (123), Expect = 2e-06
Identities = 92/391 (23%), Positives = 178/391 (45%), Gaps = 47/391 (12%)
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMV-VPEIIDSLTEVINTLTNGFESLEEVALEI 151
+L KL ED LE R NI+ ++ + + ID L N ++ E+++ +
Sbjct: 617 ELSKLKED----LEIEHRINIEKLKDNLGIHYKQQIDGLQ---NEMSQKIETMQFEKDNL 669
Query: 152 DLKKNSITKDNISIKTLLDKLI-TKNET---DINELRNSIKYLESVKSEYNTANEKLFE- 206
K+N + + +K L L+ +K+E INEL+ I+ L + E T +++ E
Sbjct: 670 ITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL 729
Query: 207 QLNNAV------DKQNCIQEEVDLLKIENQNLL-QXXXXXXXXXXXXXXXXXARDKFIAN 259
QL + +K+N +QE+ L+ EN L + R F+ +
Sbjct: 730 QLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDS 789
Query: 260 LEEMKTMLVEEKLSEIK-EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
++ V EK EI E++E+ KQ+ LNE++ R F + EKN +V
Sbjct: 790 IKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTF--SFAEKNF-------EV 840
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENN---SYKLIENMFNKVSQIASDFKISNQLSCELD 375
N +EL+E+ L + + L D++N YK N+ + + ++ +
Sbjct: 841 N--YQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 898
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKER 435
DE + T+ +L + ++ T T++ E + + L E ++++DL+EQ LK++
Sbjct: 899 DE-DKTFVAETLEMGEVVEKDT---TELMEKLEVTKREKL-ELSQRLSDLSEQ---LKQK 950
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
++ N+ E+++++ E+V+L ++
Sbjct: 951 HGEISFLNE----EVKSLKQEKEQVSLRCRE 977
Score = 51.2 bits (117), Expect = 9e-06
Identities = 72/307 (23%), Positives = 139/307 (45%), Gaps = 26/307 (8%)
Query: 173 ITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL 232
IT NE I + +I L + N+ EKL E+L ++++ +Q +++ L E
Sbjct: 462 ITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFS 521
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLV--EEKLSEIKEKDE----NFKQEI 286
+ K ++ +E++K +V E E++ K E N+K ++
Sbjct: 522 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 581
Query: 287 DMLNEK--LICDR-REFNETMQEK---NILLS---DLSKKVNKTERE----LEEKQEQL- 332
+ML ++ + DR E E E+ +L S +LSK E E +E+ ++ L
Sbjct: 582 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLG 641
Query: 333 THLMEQLNDTENNSYKLIENM-FNKVSQIASDFKISNQLS--CELDDESENT-YERISLT 388
H +Q++ +N + IE M F K + I ++ ++S +L N+ E ++L
Sbjct: 642 IHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ 701
Query: 389 LDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++++ I L + E T + + +L + + + E+ L+E+ +QLE EN L
Sbjct: 702 INELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSIL 761
Query: 447 LIEIQTV 453
E +T+
Sbjct: 762 KDEKKTL 768
Score = 45.2 bits (102), Expect = 6e-04
Identities = 56/335 (16%), Positives = 145/335 (43%), Gaps = 22/335 (6%)
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
LE + E+ K++ I + N ++ + T+ + E +IK + + ++ ++
Sbjct: 138 LEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQ 197
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNL-LQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ + + + + E+ L+I+ Q L A+ + + + ++
Sbjct: 198 ARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQ 257
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC-----DRREFN---ETMQEKNILLSDL 314
++ + L + ++K E+F +I L EK+ D++ N E +QEK ++ +L
Sbjct: 258 LEEQ--DHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 315
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ K+ + E++ E +++LT + L + + + + + N ++ + + Q S E+
Sbjct: 316 NTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEI 375
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII--- 431
+ T E L K + + T I + + + + L + + ++ ++ Q I+
Sbjct: 376 -KQLMGTVEE----LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMK 430
Query: 432 ---LKERLSQLETENKELLIEIQTVRGSNEEVTLN 463
+++ ++Q+E E++ S +T+N
Sbjct: 431 QELIRQHMAQMEEMKTRHKGEMENALRSYSNITVN 465
Score = 36.3 bits (80), Expect = 0.26
Identities = 75/345 (21%), Positives = 146/345 (42%), Gaps = 35/345 (10%)
Query: 127 IDSLTEVINTLTN-GFE-SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR 184
+ SL + + T+T+ G E S+ +V + + +D +S + + +K E I +
Sbjct: 997 VSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHL 1056
Query: 185 NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
S+ S+++ + N+KL ++LN +QN ++ L++E Q +
Sbjct: 1057 PSVTKESSLRATQPSENDKLQKELNVLKSEQNDLR-----LQMEAQRICLSLVYSTHVDQ 1111
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
+DK + +L+E EEK+ E+ Q+I L E +E +
Sbjct: 1112 VREYMENEKDKALCSLKEELIFAQEEKIKEL--------QKIHQL-ELQTMKTQETGDEG 1162
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+ ++L+ L K V+ EE L L L + + K N +K + + D+
Sbjct: 1163 KPLHLLIGKLQKAVS------EECSYFLQTLCSVLGEYYTPALKCEVNAEDK--ENSGDY 1214
Query: 365 KISNQLSCELDD---ESENTYERISLTLDKIT---NHITYLNTQINET--QKNDNAQLLW 416
IS EL D E ++ E + L+K+T N + L T++++ Q+ D +L +
Sbjct: 1215 -ISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEF 1273
Query: 417 EAKKQIADLTEQNIILKE--RLSQLETENKELLIEIQTVRGSNEE 459
+ + TE I + L ++ +K L +Q + + E
Sbjct: 1274 GEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLE 1318
Score = 33.5 bits (73), Expect = 1.8
Identities = 16/82 (19%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
EE + + + +++ +++ D N K ++ L + ++ + E +QE L+S L +++ +
Sbjct: 1281 EETEFLSIHSQMTNLEDIDVNHKSKLSSLQD---LEKTKLEEQVQELESLISSLQQQLKE 1337
Query: 321 TERELEEKQEQLTHLMEQLNDT 342
TE+ E + L ++ ++++
Sbjct: 1338 TEQNYEAEIHCLQKRLQAVSES 1359
>Y12490-1|CAA73095.1| 1979|Homo sapiens Golgi-associated
microtubule-binding protein protein.
Length = 1979
Score = 53.2 bits (122), Expect = 2e-06
Identities = 85/474 (17%), Positives = 204/474 (43%), Gaps = 44/474 (9%)
Query: 10 ANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXX 69
A+ + + I + L + + I +L++ LQQ G V E +I M + +
Sbjct: 242 AHQQKLTEISRRHREELSDYEERIEELENLLQQ----GGSGVIETDLSKIYEMQKTIQVL 297
Query: 70 XXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDS 129
T+K+ E K D+ K + ++ + L+RE Q++ ++ E +
Sbjct: 298 QIEKVES----TKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENL 353
Query: 130 LTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKY 189
E + + + + +K I + S++ + + + +++ N I
Sbjct: 354 KLECSKLQPSAVKQSDTMT-----EKERILAQSASVEE-----VFRLQQALSDAENEIMR 403
Query: 190 LESVKSEYNTANEKLFEQLN-NAVDKQNCI--QE----EVDLLKIENQ-NLLQXXXXXXX 241
L S+ + + A + L ++ ++K+ + QE ++ LLK+ N+ +++
Sbjct: 404 LSSLNQDNSLAEDNLKLKMRIEVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDI 463
Query: 242 XXXX----XXXXXXARDKFI-ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICD 296
A+++ + ++ E +T++ E + E+ +++ + + ++ ++L
Sbjct: 464 SLDSELHDLRLNLEAKEQELNQSISEKETLIAE--IEELDRQNQEATKHMILIKDQLSKQ 521
Query: 297 RREFNETMQEKNILLSDLSKKVNKTE-------RELEEKQEQLTHLMEQLNDTENNSYKL 349
+ E + + + L+D K+V++ E +EL+ ++E+L LND KL
Sbjct: 522 QNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKLIQSEVALNDLHLTKQKL 581
Query: 350 IENMFNKVSQI--ASDFKISNQL-SCELDDESENTYERISLTLDKITNHITY-LNTQINE 405
+ + N V Q+ + + +S Q + EL + E +S +++ + N+ +
Sbjct: 582 EDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIRNELMQSLNQDSNSNFKD 641
Query: 406 TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
T + + K+ +++L + N LK+ ++ EN++L++ + VR EE
Sbjct: 642 TLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVLACEDVRHQLEE 695
Score = 53.2 bits (122), Expect = 2e-06
Identities = 108/530 (20%), Positives = 207/530 (39%), Gaps = 41/530 (7%)
Query: 27 EECYKEIGQLKSGLQQNVGVGDKTVAELKND--EINSMIRQLXXXXXXXXXXXXXLTEKL 84
+E K + +K L + GD +++LK D + + QL EKL
Sbjct: 505 QEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKL 564
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+E NDL + ++E L + + S+V + E ++ +
Sbjct: 565 IQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIR 624
Query: 145 EEVALEIDLKKNSITKDNISIKTLLD-KLITKNETDINELRNSIKYLE-SVKSEYNT--- 199
E+ ++ NS KD + + + + + +N +++ +L ++K + VK E
Sbjct: 625 NELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVL 684
Query: 200 ANEKLFEQLNNAVDKQNCIQEE----VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
A E + QL + N + E V+ LK+E + +
Sbjct: 685 ACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIE 744
Query: 256 FIANLEEMKT---MLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
++N + T L E L ++ +K + E+ E++ D +E + +
Sbjct: 745 ELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQK 804
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK---LIENMFNKVSQIASDFKISNQ 369
L++ +NK E +E+ +E+ + L E+L+ K L + + K + S + +N
Sbjct: 805 QLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNH 864
Query: 370 LSCEL----DDESENTYERISLTLDKIT---NHITYLNT-------------QINETQKN 409
L EL +++S TLD +T + ++ LNT +I E Q
Sbjct: 865 LQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQ 924
Query: 410 DNAQL---LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ-TVRGSNEEVTLNLK 465
QL L E KK++ + Q+ + +QL E E + +Q T+ ++ +
Sbjct: 925 SKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQ 984
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
D T S IE+ K K++ E L +K+++ E+KL
Sbjct: 985 DIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKL 1034
Score = 41.9 bits (94), Expect = 0.005
Identities = 95/444 (21%), Positives = 182/444 (40%), Gaps = 55/444 (12%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMV--VPEIIDSLTE---VI 134
L KL I + + L SA L A K E + +S+++ + E+ SL E I
Sbjct: 1305 LLGKLDIISPQLSSASLLTPQSAECLRASKSE-VLSESSELLQQELEELRKSLQEKDATI 1363
Query: 135 NTLT-NGFESLEEVALEIDLKKNSITKDNISIKTLLDK--LITK--NETDINELRNSIKY 189
TL N + +A +L++ + + IK L +K ++ K E D+ S +
Sbjct: 1364 RTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQL 1423
Query: 190 LESVKSEYNTANEK--LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
L S ++ N NE L + + N ++ ++ ++ LK EN+ +++
Sbjct: 1424 LSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQ 1483
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNE----- 302
KF L E E + +KEK F+Q +L EK E N+
Sbjct: 1484 ETNM---KFSMMLREK-----EFECHSMKEKALAFEQ---LLKEKEQGKTGELNQLLNAV 1532
Query: 303 -TMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
+MQEK ++ +V ++ + + L + +++L D E S + +E + N + + +
Sbjct: 1533 KSMQEKTVVFQQERDQVMLALKQKQMENTALQNEVQRLRDKEFRSNQELERLRNHLLE-S 1591
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQ 421
D L+ E D +++++ +K+ ++ + +NA +A Q
Sbjct: 1592 EDSYTREALAAE--DREAKLRKKVTVLEEKL----------VSSSNAMENAS--HQASVQ 1637
Query: 422 IADLTEQ-NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD-SSTXXXXXXXXXX 479
+ L EQ N++ K+R E +++ + ++ L+L +
Sbjct: 1638 VESLQEQLNVVSKQR--------DETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKA 1689
Query: 480 XXSNEIEDMKTKVMEWKSQFEDLD 503
S E+E K + EWK E+L+
Sbjct: 1690 MYSAELEKQKQLIAEWKKNAENLE 1713
Score = 41.5 bits (93), Expect = 0.007
Identities = 56/275 (20%), Positives = 124/275 (45%), Gaps = 27/275 (9%)
Query: 257 IANLEEMKTM-LVEEKLSEIKEKDENFKQEIDMLN---EKLICDRREFNETMQEKNILLS 312
I +E K M +E+K+ +I +K + + + D+L E+L ++R+ E + + S
Sbjct: 299 IEKVESTKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECS 358
Query: 313 DLSKKVNKTERELEEKQ---------EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
L K + EK+ E++ L + L+D EN +L + N+ + +A D
Sbjct: 359 KLQPSAVKQSDTMTEKERILAQSASVEEVFRLQQALSDAENEIMRL--SSLNQDNSLAED 416
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
+ ++ E+ ++ ++ +S +++ + LN + + + ++ ++
Sbjct: 417 -NLKLKMRIEVLEKEKSL---LSQEKEELQMSLLKLNNEYEVIKSTATRDISLDS--ELH 470
Query: 424 DLTEQNIILKER-LSQLETENKELLIEIQTVRGSNEEVT---LNLKDS-STXXXXXXXXX 478
DL N+ KE+ L+Q +E + L+ EI+ + N+E T + +KD S
Sbjct: 471 DL-RLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSII 529
Query: 479 XXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
++ D K +V + + D+ + Q+++L
Sbjct: 530 SKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKL 564
Score = 32.7 bits (71), Expect = 3.2
Identities = 49/221 (22%), Positives = 90/221 (40%), Gaps = 19/221 (8%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
+ LE + + ++S T++ ++ + KL K +L +S +E+ + +
Sbjct: 1579 QELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQV 1638
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK--FIAN 259
E L EQLN V KQ ++E L +Q ++ +K + A
Sbjct: 1639 ESLQEQLN-VVSKQ---RDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAE 1694
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
LE+ K ++ +E K+ EN + ++ L E L E N + + L L K
Sbjct: 1695 LEKQKQLI-----AEWKKNAENLEGKVISLQECL----DEANAALDSASRLTEQLDVK-- 1743
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
E ++EE + Q E L+D + L + KV ++
Sbjct: 1744 --EEQIEELKRQNELRQEMLDDVQKKLMSLANSSEGKVDKV 1782
>BX641024-1|CAE46015.1| 1694|Homo sapiens hypothetical protein
protein.
Length = 1694
Score = 53.2 bits (122), Expect = 2e-06
Identities = 108/530 (20%), Positives = 207/530 (39%), Gaps = 41/530 (7%)
Query: 27 EECYKEIGQLKSGLQQNVGVGDKTVAELKND--EINSMIRQLXXXXXXXXXXXXXLTEKL 84
+E K + +K L + GD +++LK D + + QL EKL
Sbjct: 220 QEATKHMILIKDQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKL 279
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+E NDL + ++E L + + S+V + E ++ +
Sbjct: 280 IQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIR 339
Query: 145 EEVALEIDLKKNSITKDNISIKTLLD-KLITKNETDINELRNSIKYLE-SVKSEYNT--- 199
E+ ++ NS KD + + + + + +N +++ +L ++K + VK E
Sbjct: 340 NELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVL 399
Query: 200 ANEKLFEQLNNAVDKQNCIQEE----VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
A E + QL + N + E V+ LK+E + +
Sbjct: 400 ACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIE 459
Query: 256 FIANLEEMKT---MLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
++N + T L E L ++ +K + E+ E++ D +E + +
Sbjct: 460 ELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQK 519
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK---LIENMFNKVSQIASDFKISNQ 369
L++ +NK E +E+ +E+ + L E+L+ K L + + K + S + +N
Sbjct: 520 QLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNH 579
Query: 370 LSCEL----DDESENTYERISLTLDKIT---NHITYLNT-------------QINETQKN 409
L EL +++S TLD +T + ++ LNT +I E Q
Sbjct: 580 LQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQ 639
Query: 410 DNAQL---LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ-TVRGSNEEVTLNLK 465
QL L E KK++ + Q+ + +QL E E + +Q T+ ++ +
Sbjct: 640 SKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQ 699
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
D T S IE+ K K++ E L +K+++ E+KL
Sbjct: 700 DIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKL 749
Score = 50.0 bits (114), Expect = 2e-05
Identities = 80/387 (20%), Positives = 165/387 (42%), Gaps = 33/387 (8%)
Query: 81 TEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNG 140
T+K+ E K D+ K + ++ + L+RE Q++ ++ E + E +
Sbjct: 49 TKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSA 108
Query: 141 FESLEEVALEIDLKKNSITKDNISIKTL--LDKLITKNETDINELRNSIKYLESVKSEYN 198
+ + + +K I + S++ + L + ++ E +I L +S+ E S
Sbjct: 109 VKQSDTMT-----EKERILAQSASVEEVFRLQQALSDAENEIMRL-SSLNQEELQMSLLK 162
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
NE +E + + + + E+ L++ NL ++ IA
Sbjct: 163 LNNE--YEVIKSTATRDISLDSELHDLRL---NL-------EAKEQELNQSISEKETLIA 210
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQ--EIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
+EE+ E I KD+ KQ E D + KL +++ N+ + + L D
Sbjct: 211 EIEELDRQNQEATKHMILIKDQLSKQQNEGDSIISKL---KQDLNDEKKRVHQLEDD--- 264
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI--ASDFKISNQL-SCE 373
K++ T +EL+ ++E+L LND KL + + N V Q+ + + +S Q + E
Sbjct: 265 KMDIT-KELDVQKEKLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLE 323
Query: 374 LDDESENTYERISLTLDKITNHITY-LNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL 432
L + E +S +++ + N+ +T + + K+ +++L + N L
Sbjct: 324 LKEHIRQNEEELSRIRNELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENL 383
Query: 433 KERLSQLETENKELLIEIQTVRGSNEE 459
K+ ++ EN++L++ + VR EE
Sbjct: 384 KKVAFDVKMENEKLVLACEDVRHQLEE 410
Score = 43.6 bits (98), Expect = 0.002
Identities = 95/444 (21%), Positives = 183/444 (41%), Gaps = 55/444 (12%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMV--VPEIIDSLTE---VI 134
L KL I + + L SA L A K E + +S+++ + E+ SL E I
Sbjct: 1020 LLGKLDIISPQLSSASLLTPQSAECLRASKSE-VLSESSELLQQELEELRKSLQEKDATI 1078
Query: 135 NTLT-NGFESLEEVALEIDLKKNSITKDNISIKTLLDK--LITK--NETDINELRNSIKY 189
TL N + +A +L++ + + IK L +K ++ K E D+ S +
Sbjct: 1079 RTLQENNHRLSDSIAATSELERKEHEQTDSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQL 1138
Query: 190 LESVKSEYNTANEK--LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
L S ++ N NE L + + N ++ ++ ++ LK EN+ +++
Sbjct: 1139 LSSNENFTNKVNENELLRQAVTNLKERILILEMDIGKLKGENEKIVETYRGKETEYQALQ 1198
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNE----- 302
KF L E E + +KEK F+Q +L EK E N+
Sbjct: 1199 ETNM---KFSMMLREK-----EFECHSMKEKALAFEQ---LLKEKEQGKTGELNQLLNAV 1247
Query: 303 -TMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
+MQEK ++ +V ++ + + L +++++L D E S + +E + N + + +
Sbjct: 1248 KSMQEKTVVFQQERDQVMLALKQKQMENTALQNVVQRLRDKEFRSNQELERLRNHLLE-S 1306
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQ 421
D L+ E D +++++ +K+ ++ + +NA +A Q
Sbjct: 1307 EDSYTREALAAE--DREAKLRKKVTVLEEKL----------VSSSNAMENAS--HQASVQ 1352
Query: 422 IADLTEQ-NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD-SSTXXXXXXXXXX 479
+ L EQ N++ K+R E +++ + ++ L+L +
Sbjct: 1353 VESLQEQLNVVSKQR--------DETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKA 1404
Query: 480 XXSNEIEDMKTKVMEWKSQFEDLD 503
S E+E K + EWK E+L+
Sbjct: 1405 MYSAELEKQKQLIAEWKKNAENLE 1428
Score = 37.9 bits (84), Expect = 0.085
Identities = 56/275 (20%), Positives = 118/275 (42%), Gaps = 25/275 (9%)
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
+EE++ +L ++ S + E D + E+ + L ++ E + M++ + D++KK++
Sbjct: 9 IEELENLL-QQGGSGVIETDLSKIYEMQKTIQVLQIEKVESTKKMEQLEDKIKDINKKLS 67
Query: 320 KTERE---LEEKQEQLT----HLMEQLNDTENNSYKL-------IENMFNKVSQIASDFK 365
E + L +QEQL +ME+ + + KL + M K +A
Sbjct: 68 SAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSAVKQSDTMTEKERILAQSAS 127
Query: 366 ISN--QLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
+ +L L D SL +++ + LN + + + ++ ++
Sbjct: 128 VEEVFRLQQALSDAENEIMRLSSLNQEELQMSLLKLNNEYEVIKSTATRDISLDS--ELH 185
Query: 424 DLTEQNIILKER-LSQLETENKELLIEIQTVRGSNEEVT---LNLKDS-STXXXXXXXXX 478
DL N+ KE+ L+Q +E + L+ EI+ + N+E T + +KD S
Sbjct: 186 DL-RLNLEAKEQELNQSISEKETLIAEIEELDRQNQEATKHMILIKDQLSKQQNEGDSII 244
Query: 479 XXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
++ D K +V + + D+ + Q+++L
Sbjct: 245 SKLKQDLNDEKKRVHQLEDDKMDITKELDVQKEKL 279
Score = 32.7 bits (71), Expect = 3.2
Identities = 49/221 (22%), Positives = 90/221 (40%), Gaps = 19/221 (8%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
+ LE + + ++S T++ ++ + KL K +L +S +E+ + +
Sbjct: 1294 QELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNAMENASHQASVQV 1353
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK--FIAN 259
E L EQLN V KQ ++E L +Q ++ +K + A
Sbjct: 1354 ESLQEQLN-VVSKQ---RDETALQLSVSQEQVKQYALSLANLQMVLEHFQQEEKAMYSAE 1409
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
LE+ K ++ +E K+ EN + ++ L E L E N + + L L K
Sbjct: 1410 LEKQKQLI-----AEWKKNAENLEGKVISLQECL----DEANAALDSASRLTEQLDVK-- 1458
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
E ++EE + Q E L+D + L + KV ++
Sbjct: 1459 --EEQIEELKRQNELRQEMLDDVQKKLMSLANSSEGKVDKV 1497
>BC114545-1|AAI14546.1| 1939|Homo sapiens myosin, heavy chain 1,
skeletal muscle, adult protein.
Length = 1939
Score = 53.2 bits (122), Expect = 2e-06
Identities = 87/444 (19%), Positives = 180/444 (40%), Gaps = 31/444 (6%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L EK+ + NDL+ + A L + D ++ +I L I +T
Sbjct: 877 LEEKMVTLMQEKNDLQLQVQAEADSLADAEER------CDQLIKTKI--QLEAKIKEVTE 928
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYLESVKSE 196
E EE+ E+ KK + + +K +D L + K E + + N +K L +
Sbjct: 929 RAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 988
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXXXXXARD 254
+ KL ++ A+ Q Q+ +D L+ E N L ++
Sbjct: 989 LDETIAKLTKE-KKAL--QEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQE 1045
Query: 255 KFIA-NLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
K I +LE K L + KL++ D EN KQ++D +K + ++++ L
Sbjct: 1046 KKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALG 1105
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
L KK+ + + +EE +E++ E L + ++S+ + +
Sbjct: 1106 MQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL-EEISERLEEAGGATSAQ 1164
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
E++ + E ++++ L++ T + T + +A + E +QI +L
Sbjct: 1165 IEMNKKREAEFQKMRRDLEE----ATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1220
Query: 432 LKERLSQLETENKELLIEIQTV---RGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDM 488
L++ S+++ E +L ++TV +G+ E++ L+D + N++
Sbjct: 1221 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQ 1280
Query: 489 KTKVM----EWKSQFEDLDDVMKQ 508
+ ++ E+ Q ++ D ++ Q
Sbjct: 1281 RARLQTESGEYSRQLDEKDTLVSQ 1304
Score = 51.2 bits (117), Expect = 9e-06
Identities = 76/427 (17%), Positives = 175/427 (40%), Gaps = 39/427 (9%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVMV--------VPEIIDSLTEVINTLTNGFES 143
+K YE+S +LE LKRE N+Q SD+ + E+ +V + +
Sbjct: 1488 IKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQAA 1547
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLDKLITKNETDINEL-RNSIKYLESVKSEYNT 199
LEE ++ ++ I + + +K+ +D+ I + + +I+++ RN I+ +ES++S +
Sbjct: 1548 LEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDA 1607
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
+ + + + E L N+ + D + +
Sbjct: 1608 EIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRS 1667
Query: 260 LEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
E++K L VE + + ++ + E + ++ +E + + +L + +
Sbjct: 1668 QEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSL 1727
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE 377
+N T+++LE Q+ ME + N+ + + + +A + K S L
Sbjct: 1728 IN-TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL--- 1783
Query: 378 SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS 437
ER+ L++ + + +++E ++ L KKQI L + ++E
Sbjct: 1784 -----ERMKKNLEQTVKDLQH---RLDEAEQ----LALKGGKKQIQKLEAR---VRELEG 1828
Query: 438 QLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKS 497
++E+E K ++ V+G + +K+ + + ++ ++ KV +K
Sbjct: 1829 EVESEQKR---NVEAVKGLRKH-ERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKR 1884
Query: 498 QFEDLDD 504
Q E+ ++
Sbjct: 1885 QAEEAEE 1891
Score = 51.2 bits (117), Expect = 9e-06
Identities = 50/264 (18%), Positives = 113/264 (42%), Gaps = 19/264 (7%)
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL---LSDLSKKVNKTERELE 326
++L +K +++N +QEI L E++ + +E + K + S+L + + E LE
Sbjct: 1497 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELKKIKKQVEQEKSELQAALEEAEASLE 1556
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQLSCELDDESENTYERI 385
++ ++ + +LN ++ + I ++ Q+ + +I + LD E + + I
Sbjct: 1557 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAI 1616
Query: 386 SLT------LDKITNHITYLNTQINETQKN---------DNAQLLWEAKKQIADLTEQNI 430
L L+++ + + N E +N D L +A + DL EQ
Sbjct: 1617 RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLA 1676
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKT 490
+++ R + L+ E +EL ++ S + L D+S N + ++T
Sbjct: 1677 MVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLET 1736
Query: 491 KVMEWKSQFEDLDDVMKQQQKELK 514
+ + + + ED+ + +++ K
Sbjct: 1737 DISQIQGEMEDIIQEARNAEEKAK 1760
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/235 (20%), Positives = 104/235 (44%), Gaps = 9/235 (3%)
Query: 220 EEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD 279
E++D L+ Q L + K NLE+M L E++LSEIK K+
Sbjct: 1209 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRAL-EDQLSEIKTKE 1267
Query: 280 ENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM 336
E ++ I+ L +L + E++ + EK+ L+S LS+ +++EE + QL
Sbjct: 1268 EEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLE--- 1324
Query: 337 EQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHI 396
E++ ++ L ++ + + ++ + EL ++ K
Sbjct: 1325 EEIKAKSALAHAL-QSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDA 1383
Query: 397 TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
++ E +K AQ L +A++ + + + L++ +L+ E ++L+I+++
Sbjct: 1384 IQRTEELEEAKKK-LAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVE 1437
Score = 39.1 bits (87), Expect = 0.037
Identities = 34/204 (16%), Positives = 93/204 (45%), Gaps = 3/204 (1%)
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+++ KTE + +E +E++ LM++ ND + +++ + + K QL ++
Sbjct: 865 EELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIK 924
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAKKQIADLTEQNI-ILK 433
+ +E + + + +T L + +E +K+ D+ +L ++ TE + L
Sbjct: 925 EVTERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 983
Query: 434 ERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
E ++ L+ +L E + ++ ++++ +L+ +++D++ +
Sbjct: 984 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLE 1043
Query: 494 EWKSQFEDLDDVMKQQQKELKLGK 517
+ K DL+ ++ + +LKL +
Sbjct: 1044 QEKKIRMDLERAKRKLEGDLKLAQ 1067
Score = 33.5 bits (73), Expect = 1.8
Identities = 41/205 (20%), Positives = 93/205 (45%), Gaps = 12/205 (5%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
K +TE+E+ +E+ E+L TE +L E M + Q +D ++ Q +
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVT-LMQEKNDLQLQVQAEADSLA 903
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKK---QIADLTEQNIILK 433
++E +++ T ++ I + T+ E ++ NA+L + +K + ++L + L+
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEV-TERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 434 ERLSQLE-----TEN--KELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIE 486
L+++E TEN K L E+ + + ++T K +++
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1022
Query: 487 DMKTKVMEWKSQFEDLDDVMKQQQK 511
+ ++ + Q +DL+ ++Q++K
Sbjct: 1023 TLTKAKIKLEQQVDDLEGSLEQEKK 1047
>AF111785-1|AAD29951.1| 1939|Homo sapiens myosin heavy chain IIx/d
protein.
Length = 1939
Score = 53.2 bits (122), Expect = 2e-06
Identities = 87/444 (19%), Positives = 180/444 (40%), Gaps = 31/444 (6%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L EK+ + NDL+ + A L + D ++ +I L I +T
Sbjct: 877 LEEKMVTLMQEKNDLQLQVQAEADSLADAEER------CDQLIKTKI--QLEAKIKEVTE 928
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYLESVKSE 196
E EE+ E+ KK + + +K +D L + K E + + N +K L +
Sbjct: 929 RAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLTEEMAG 988
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXXXXXARD 254
+ KL ++ A+ Q Q+ +D L+ E N L ++
Sbjct: 989 LDETIAKLTKE-KKAL--QEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLEQE 1045
Query: 255 KFIA-NLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
K I +LE K L + KL++ D EN KQ++D +K + ++++ L
Sbjct: 1046 KKIRMDLERAKRKLEGDLKLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALG 1105
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
L KK+ + + +EE +E++ E L + ++S+ + +
Sbjct: 1106 MQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL-EEISERLEEAGGATSAQ 1164
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
E++ + E ++++ L++ T + T + +A + E +QI +L
Sbjct: 1165 IEMNKKREAEFQKMRRDLEE----ATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQK 1220
Query: 432 LKERLSQLETENKELLIEIQTV---RGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDM 488
L++ S+++ E +L ++TV +G+ E++ L+D + N++
Sbjct: 1221 LEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQ 1280
Query: 489 KTKVM----EWKSQFEDLDDVMKQ 508
+ ++ E+ Q ++ D ++ Q
Sbjct: 1281 RARLQTESGEYSRQLDEKDTLVSQ 1304
Score = 51.2 bits (117), Expect = 9e-06
Identities = 76/427 (17%), Positives = 175/427 (40%), Gaps = 39/427 (9%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVMV--------VPEIIDSLTEVINTLTNGFES 143
+K YE+S +LE LKRE N+Q SD+ + E+ +V + +
Sbjct: 1488 IKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAA 1547
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLDKLITKNETDINEL-RNSIKYLESVKSEYNT 199
LEE ++ ++ I + + +K+ +D+ I + + +I+++ RN I+ +ES++S +
Sbjct: 1548 LEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDA 1607
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
+ + + + E L N+ + D + +
Sbjct: 1608 EIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRS 1667
Query: 260 LEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
E++K L VE + + ++ + E + ++ +E + + +L + +
Sbjct: 1668 QEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSL 1727
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE 377
+N T+++LE Q+ ME + N+ + + + +A + K S L
Sbjct: 1728 IN-TKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL--- 1783
Query: 378 SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS 437
ER+ L++ + + +++E ++ L KKQI L + ++E
Sbjct: 1784 -----ERMKKNLEQTVKDLQH---RLDEAEQ----LALKGGKKQIQKLEAR---VRELEG 1828
Query: 438 QLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKS 497
++E+E K ++ V+G + +K+ + + ++ ++ KV +K
Sbjct: 1829 EVESEQKR---NVEAVKGLRKH-ERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKR 1884
Query: 498 QFEDLDD 504
Q E+ ++
Sbjct: 1885 QAEEAEE 1891
Score = 50.8 bits (116), Expect = 1e-05
Identities = 50/264 (18%), Positives = 113/264 (42%), Gaps = 19/264 (7%)
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL---LSDLSKKVNKTERELE 326
++L +K +++N +QEI L E++ + +E + K + S+L + + E LE
Sbjct: 1497 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLE 1556
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQLSCELDDESENTYERI 385
++ ++ + +LN ++ + I ++ Q+ + +I + LD E + + I
Sbjct: 1557 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAI 1616
Query: 386 SLT------LDKITNHITYLNTQINETQKN---------DNAQLLWEAKKQIADLTEQNI 430
L L+++ + + N E +N D L +A + DL EQ
Sbjct: 1617 RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLA 1676
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKT 490
+++ R + L+ E +EL ++ S + L D+S N + ++T
Sbjct: 1677 MVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLET 1736
Query: 491 KVMEWKSQFEDLDDVMKQQQKELK 514
+ + + + ED+ + +++ K
Sbjct: 1737 DISQIQGEMEDIIQEARNAEEKAK 1760
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/235 (20%), Positives = 104/235 (44%), Gaps = 9/235 (3%)
Query: 220 EEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD 279
E++D L+ Q L + K NLE+M L E++LSEIK K+
Sbjct: 1209 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRAL-EDQLSEIKTKE 1267
Query: 280 ENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM 336
E ++ I+ L +L + E++ + EK+ L+S LS+ +++EE + QL
Sbjct: 1268 EEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGKQAFTQQIEELKRQLE--- 1324
Query: 337 EQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHI 396
E++ ++ L ++ + + ++ + EL ++ K
Sbjct: 1325 EEIKAKSALAHAL-QSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDA 1383
Query: 397 TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
++ E +K AQ L +A++ + + + L++ +L+ E ++L+I+++
Sbjct: 1384 IQRTEELEEAKKK-LAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVE 1437
Score = 39.1 bits (87), Expect = 0.037
Identities = 34/204 (16%), Positives = 93/204 (45%), Gaps = 3/204 (1%)
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+++ KTE + +E +E++ LM++ ND + +++ + + K QL ++
Sbjct: 865 EELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQLEAKIK 924
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAKKQIADLTEQNI-ILK 433
+ +E + + + +T L + +E +K+ D+ +L ++ TE + L
Sbjct: 925 EVTERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNLT 983
Query: 434 ERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
E ++ L+ +L E + ++ ++++ +L+ +++D++ +
Sbjct: 984 EEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLEGSLE 1043
Query: 494 EWKSQFEDLDDVMKQQQKELKLGK 517
+ K DL+ ++ + +LKL +
Sbjct: 1044 QEKKIRMDLERAKRKLEGDLKLAQ 1067
Score = 33.5 bits (73), Expect = 1.8
Identities = 41/205 (20%), Positives = 93/205 (45%), Gaps = 12/205 (5%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
K +TE+E+ +E+ E+L TE +L E M + Q +D ++ Q +
Sbjct: 845 KSAETEKEMANMKEEFEKTKEELAKTEAKRKELEEKMVT-LMQEKNDLQLQVQAEADSLA 903
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKK---QIADLTEQNIILK 433
++E +++ T ++ I + T+ E ++ NA+L + +K + ++L + L+
Sbjct: 904 DAEERCDQLIKTKIQLEAKIKEV-TERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE 962
Query: 434 ERLSQLE-----TEN--KELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIE 486
L+++E TEN K L E+ + + ++T K +++
Sbjct: 963 LTLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVN 1022
Query: 487 DMKTKVMEWKSQFEDLDDVMKQQQK 511
+ ++ + Q +DL+ ++Q++K
Sbjct: 1023 TLTKAKIKLEQQVDDLEGSLEQEKK 1047
>BC033545-1|AAH33545.1| 700|Homo sapiens cancer antigen 1 protein.
Length = 700
Score = 52.8 bits (121), Expect = 3e-06
Identities = 47/217 (21%), Positives = 104/217 (47%), Gaps = 12/217 (5%)
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
K + NLEE+ ++ L E + E + + + +C + + MQ+KN +S
Sbjct: 380 KTLQNLEEVLAN-TQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQY 438
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ ++KT + EE+ E+L L ++L ++ L++ K +Q + + +L
Sbjct: 439 LE-MDKTLSKKEEEVERLQQLKKELEKATASALDLLKR--EKEAQEQEFLSLQEEFQ-KL 494
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ E+ +++ L+K+ + L ++E ++ N +L ++QI ++ +N LK+
Sbjct: 495 EKENLEERQKLKSRLEKLLTQVRNLQF-MSENERTKNIKL----QQQINEVKNENAKLKQ 549
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLN--LKDSST 469
++++ E +N E ++ EEV + KD+ T
Sbjct: 550 QVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKT 586
Score = 39.5 bits (88), Expect = 0.028
Identities = 42/213 (19%), Positives = 89/213 (41%), Gaps = 13/213 (6%)
Query: 132 EVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLE 191
+VIN L E L E +I L+KN TK + L++++ + + E RN + L+
Sbjct: 352 DVINKLKENVEELIEDKYKIILEKND-TKKTLQ---NLEEVLANTQKHLQESRNDKEMLQ 407
Query: 192 ----SVKSEYNTANEKLFEQL--NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
+K+ Y E+ ++ N Q ++ K E LQ
Sbjct: 408 LQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATA 467
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQ 305
R+K +E + + ++E+ ++++++ +Q++ EKL+ R +
Sbjct: 468 SALDLLKREK---EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSE 524
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ L +++N+ + E + ++Q+ EQ
Sbjct: 525 NERTKNIKLQQQINEVKNENAKLKQQVARSEEQ 557
Score = 38.3 bits (85), Expect = 0.065
Identities = 31/158 (19%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
+DK ++K E ++ L+ K LE TA+ + +Q + + + K+E
Sbjct: 441 MDKTLSKKEEEVERLQQLKKELEKA-----TASALDLLKREKEAQEQEFLSLQEEFQKLE 495
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDM 288
+NL + + F++ E K + ++++++E+K ++ KQ++
Sbjct: 496 KENLEERQKLKSRLEKLLTQVRNLQ--FMSENERTKNIKLQQQINEVKNENAKLKQQVAR 553
Query: 289 LNEKLICDRREFNETM-QEKNILLSDLSKKVNKTEREL 325
E+ + E + Q + +L SD++K T L
Sbjct: 554 SEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNL 591
Score = 37.9 bits (84), Expect = 0.085
Identities = 50/254 (19%), Positives = 91/254 (35%), Gaps = 9/254 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+M V +KL K E QE+ N L +E + ++ + + +NK
Sbjct: 301 EDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFID----VINK 356
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
+ +EE E ++ + NDT+ L E + N + L + N
Sbjct: 357 LKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKAN 416
Query: 381 ---TYERISLTLDKITNHIT-YLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
ER + + ++ YL ++K + + L + KK++ T + +LK
Sbjct: 417 YVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKRE 476
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
E E L E Q + N E LK S K+ +
Sbjct: 477 KEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQ 536
Query: 496 KSQFEDLDDVMKQQ 509
++ ++ + +KQQ
Sbjct: 537 INEVKNENAKLKQQ 550
>BC026194-1|AAH26194.1| 700|Homo sapiens cancer antigen 1 protein.
Length = 700
Score = 52.8 bits (121), Expect = 3e-06
Identities = 47/217 (21%), Positives = 104/217 (47%), Gaps = 12/217 (5%)
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
K + NLEE+ ++ L E + E + + + +C + + MQ+KN +S
Sbjct: 380 KTLQNLEEVLAN-TQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQY 438
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ ++KT + EE+ E+L L ++L ++ L++ K +Q + + +L
Sbjct: 439 LE-MDKTLSKKEEEVERLQQLKKELEKATASALDLLKR--EKEAQEQEFLSLQEEFQ-KL 494
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ E+ +++ L+K+ + L ++E ++ N +L ++QI ++ +N LK+
Sbjct: 495 EKENLEERQKLKSRLEKLLTQVRNLQF-MSENERTKNIKL----QQQINEVKNENAKLKQ 549
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLN--LKDSST 469
++++ E +N E ++ EEV + KD+ T
Sbjct: 550 QVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKT 586
Score = 39.5 bits (88), Expect = 0.028
Identities = 42/213 (19%), Positives = 89/213 (41%), Gaps = 13/213 (6%)
Query: 132 EVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLE 191
+VIN L E L E +I L+KN TK + L++++ + + E RN + L+
Sbjct: 352 DVINKLKENVEELIEDKYKIILEKND-TKKTLQ---NLEEVLANTQKHLQESRNDKEMLQ 407
Query: 192 ----SVKSEYNTANEKLFEQL--NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
+K+ Y E+ ++ N Q ++ K E LQ
Sbjct: 408 LQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATA 467
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQ 305
R+K +E + + ++E+ ++++++ +Q++ EKL+ R +
Sbjct: 468 SALDLLKREK---EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSE 524
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ L +++N+ + E + ++Q+ EQ
Sbjct: 525 NERTKNIKLQQQINEVKNENAKLKQQVARSEEQ 557
Score = 38.3 bits (85), Expect = 0.065
Identities = 31/158 (19%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
+DK ++K E ++ L+ K LE TA+ + +Q + + + K+E
Sbjct: 441 MDKTLSKKEEEVERLQQLKKELEKA-----TASALDLLKREKEAQEQEFLSLQEEFQKLE 495
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDM 288
+NL + + F++ E K + ++++++E+K ++ KQ++
Sbjct: 496 KENLEERQKLKSRLEKLLTQVRNLQ--FMSENERTKNIKLQQQINEVKNENAKLKQQVAR 553
Query: 289 LNEKLICDRREFNETM-QEKNILLSDLSKKVNKTEREL 325
E+ + E + Q + +L SD++K T L
Sbjct: 554 SEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNL 591
Score = 37.9 bits (84), Expect = 0.085
Identities = 50/254 (19%), Positives = 91/254 (35%), Gaps = 9/254 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+M V +KL K E QE+ N L +E + ++ + + +NK
Sbjct: 301 EDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFID----VINK 356
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
+ +EE E ++ + NDT+ L E + N + L + N
Sbjct: 357 LKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKAN 416
Query: 381 ---TYERISLTLDKITNHIT-YLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
ER + + ++ YL ++K + + L + KK++ T + +LK
Sbjct: 417 YVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKRE 476
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
E E L E Q + N E LK S K+ +
Sbjct: 477 KEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQ 536
Query: 496 KSQFEDLDDVMKQQ 509
++ ++ + +KQQ
Sbjct: 537 INEVKNENAKLKQQ 550
>AL139421-4|CAI22511.1| 720|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 720
Score = 52.8 bits (121), Expect = 3e-06
Identities = 94/522 (18%), Positives = 212/522 (40%), Gaps = 55/522 (10%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETK 90
+E +L S + V +G V +K+ ++M +Q L KL E +
Sbjct: 198 QESSKLSSLETEPVKLGGHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAE 257
Query: 91 HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++DLK S+ + ++ E ++ ++ + E+ ++++ TL E + VA
Sbjct: 258 NSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLL-TLEKQLEE-KIVAYS 315
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES---VKSEYNTANEKLFEQ 207
KN+ + + ++ L+K + E ++ L+ K + + ++L +
Sbjct: 316 SIAAKNAELEQELMLEAQLEK----KDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTE 371
Query: 208 LNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML 267
+ K+N ++E L ++NQ +++ + +L +++
Sbjct: 372 SKGEMKKENMKKDEA-LKALQNQ----VSEETIKVRQLDSALEICKEELVLHLNQLEGNK 426
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE--- 324
E+ ++K+K E E+ L ++L ET ++ IL L ++ ++E
Sbjct: 427 -EKFEKQLKKKSE----EVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIR 481
Query: 325 ---LEEKQ----EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD- 376
LE+ Q +Q++ L ++L +S + + M K A + + Q EL
Sbjct: 482 NGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGT 541
Query: 377 ------ESENTYERISLTLDKITN----------HITYLNTQINET----QKNDNA---- 412
E + E +S +I + H++ L+ +++T +K NA
Sbjct: 542 ARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKEL 601
Query: 413 -QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXX 471
+L + ++ + ++ +L+ L E K L ++Q +R ++ L+L++ T
Sbjct: 602 EKLQHSTETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTI 661
Query: 472 XXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
EIED K +++E ++ + +KQ+ ++
Sbjct: 662 KDLTAELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQV 703
Score = 32.3 bits (70), Expect = 4.2
Identities = 50/260 (19%), Positives = 108/260 (41%), Gaps = 14/260 (5%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDEN-FKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
+++LE L ++ +K+++++ ++ + ++L+ E + + SDL
Sbjct: 203 LSSLETEPVKLGGHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAENSDL- 261
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
KVN R Q QL + E+L + +NS KL M K SQ+ + + QL ++
Sbjct: 262 -KVNMAHRT---SQFQL--IQEELLEKASNSSKLESEMTKKCSQLLT---LEKQLEEKIV 312
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKER 435
S + L + + Q + Q+ + L + + L + +L E
Sbjct: 313 AYSSIAAKNAELEQELMLEAQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTES 372
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
+++ EN + ++ ++ E T+ ++ + N++E K K +
Sbjct: 373 KGEMKKENMKKDEALKALQNQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEK---F 429
Query: 496 KSQFEDLDDVMKQQQKELKL 515
+ Q + + + QKELK+
Sbjct: 430 EKQLKKKSEEVYCLQKELKI 449
>AL139421-3|CAI22510.1| 1044|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1044
Score = 52.8 bits (121), Expect = 3e-06
Identities = 106/498 (21%), Positives = 204/498 (40%), Gaps = 41/498 (8%)
Query: 52 AELKND--EINSMIRQLXXXXXXXXXXXXXLTEKLT-IAETKHNDLKKLYEDSASELEAL 108
AEL+ + E N IR L EK I +H +++K E ++LE
Sbjct: 348 AELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKK 407
Query: 109 KRE------NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLK--KNSITK 160
++ + M D++ ++SL ++ T + G E + + LK +N +++
Sbjct: 408 DQQFKEQEKTMSMLQQDIICKQHHLESLDRLL-TESKGEMKKENMKKDEALKALQNQVSE 466
Query: 161 DNISIKTLLDKL-ITKNET--DINELR-NSIKYLESVK--SEYNTANEKLFEQLNNAVDK 214
+ I ++ L L I K E +N+L N K+ + +K SE +K + N+++ +
Sbjct: 467 ETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQE 526
Query: 215 ---QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
QN I + L+ + Q L Q K L++ + E K
Sbjct: 527 TSEQNVILQHT--LQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAE-K 583
Query: 272 LSEIKEKDENFKQEIDMLNEKLI---CDRREFNETMQEKNILLSDLSKKVNKTERELEEK 328
L +++EK E+ E D+ +K+I R+ M + LS + K++ +R+ E K
Sbjct: 584 LRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENK 643
Query: 329 QEQLTHLMEQLNDTENNSYKLIENMFNKVSQI--ASDFKISNQLSCE--LDDESENTYER 384
L+ L L+ T+ K N ++ ++ +++ +++ L L+ E +N +
Sbjct: 644 AMHLSQLDMILDQTKTELEKK-TNAVKELEKLQHSTETELTEALQKREVLETELQNAHGE 702
Query: 385 ISLTLDKITN-----HITYLNTQINETQKNDNAQLLWEAKKQIAD----LTEQNIILKER 435
+ TL ++ L+ + T D L E K +I D L E + LKER
Sbjct: 703 LKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKER 762
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
+L+ ++ T+R E+ + + +IE + K+
Sbjct: 763 NWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNA 822
Query: 496 KSQFEDLDDVMKQQQKEL 513
K Q + + +M Q ++E+
Sbjct: 823 KEQLREKEFIMLQNEQEI 840
Score = 49.6 bits (113), Expect = 3e-05
Identities = 86/506 (16%), Positives = 204/506 (40%), Gaps = 25/506 (4%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAE-LKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAET 89
+E +L S + V +G VAE +K+ ++M +Q L KL E
Sbjct: 223 QESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEA 282
Query: 90 KHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVAL 149
+++DLK S+ + ++ E ++ ++ + E+ ++++ TL E
Sbjct: 283 ENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLL-TLEKQLEEKIVAYS 341
Query: 150 EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLN 209
I K + ++ + + L T T+ ++ + + + + E + EK E+L
Sbjct: 342 SIAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLE 401
Query: 210 NAVDK--QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML 267
++K Q ++E + ++ + + + + + E +K +
Sbjct: 402 AQLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQ 461
Query: 268 --VEEKLSEIKEKD---ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
V E+ ++++ D E K+E+ + +L ++ +F + +++K+ + L K++
Sbjct: 462 NQVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKN 521
Query: 323 RELEEKQEQ---LTHLMEQLNDT------ENNSYKLIENMFNK-VSQIASDFKISNQLSC 372
L+E EQ L H ++Q N + + K VS++ + + + S
Sbjct: 522 HSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSA 581
Query: 373 E----LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQ 428
E ++++ E+ L K+ +T Q+ + + + + L + +K+I L
Sbjct: 582 EKLRKMEEKCESAAHEADLKRQKVIE-LTGTARQV-KIEMDQYKEELSKMEKEIMHLKRD 639
Query: 429 NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDM 488
LSQL+ + E++ + +E+ + T E+++
Sbjct: 640 GENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNA 699
Query: 489 KTKVMEWKSQFEDLDDVMKQQQKELK 514
++ Q ++L DV+++ Q L+
Sbjct: 700 HGELKSTLRQLQELRDVLQKAQLSLE 725
Score = 44.0 bits (99), Expect = 0.001
Identities = 69/338 (20%), Positives = 142/338 (42%), Gaps = 29/338 (8%)
Query: 144 LEEVALEIDLKKNSITK--DNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
+ E+ +++ +K+ I K N++ L LIT N++ + +S++ E VK +
Sbjct: 186 ISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLE-TEPVKLGGHQVA 244
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E + +Q + ++KQ + E Q L+ +A+
Sbjct: 245 ESVKDQNQHTMNKQ---------YEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAH-R 294
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ L++E+L E + E+ +L+ ++ ++EK + S ++ K +
Sbjct: 295 TSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQ----LEEKIVAYSSIAAKNAEL 350
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV--SQIASDFKISNQLSCELD---- 375
E+EL EK E++ L +N TE+ L K+ Q K +L +L+
Sbjct: 351 EQELMEKNEKIRSLETNIN-TEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQ 409
Query: 376 --DESENTYERISLTLDKITNHITYLNTQINETQ---KNDNAQLLWEAKKQIADLTEQNI 430
E E T + + +H+ L+ + E++ K +N + K ++E+ I
Sbjct: 410 QFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETI 469
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
+++ S LE +EL++ + + G+ E+ LK S
Sbjct: 470 KVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKS 507
Score = 42.7 bits (96), Expect = 0.003
Identities = 75/425 (17%), Positives = 183/425 (43%), Gaps = 34/425 (8%)
Query: 104 ELEALKR--ENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKD 161
E+ LKR EN MH S + + I+D + TN + LE++ + + +
Sbjct: 632 EIMHLKRDGENKAMHLSQLDM---ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQK 688
Query: 162 NISIKTLLDKL---ITKNETDINELRNSIKYLE-SVKSEYNTANE---KLFEQLNNAVDK 214
++T L + + ELR+ ++ + S++ +Y T + +L E DK
Sbjct: 689 REVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDK 748
Query: 215 QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSE 274
+ + E LK N L Q ++ I LE T+ EK SE
Sbjct: 749 KQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEG--TL---EK-SE 802
Query: 275 IKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTH 334
++ K+ N ++I+ LN+KL + E ++EK ++ +++++ ++E+E Q+++
Sbjct: 803 LELKECN--KQIESLNDKL----QNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKE 856
Query: 335 LMEQLNDTENNSYKLIENMFNKVSQIASDFKIS-NQLSCELDDESENTYERISL--TLDK 391
+ + + E + I + + + + +++ Q+ + +E ++++ +++
Sbjct: 857 MESVMKEQE----QYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIER 912
Query: 392 ITNHITYLNTQINETQKNDN--AQLLWEAKKQIADL-TEQNIILKERLSQLETENKELLI 448
+++ + + E + N A+ L +K + A L +K+ +++E+ + +
Sbjct: 913 LSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHM 972
Query: 449 EIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQ 508
E+ + + ++ + ++ + E+E+ + V Q +D ++V++
Sbjct: 973 EMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEA 1032
Query: 509 QQKEL 513
+ L
Sbjct: 1033 ANEAL 1037
>AL139421-1|CAI22508.1| 1454|Homo sapiens coiled-coil domain
containing 18 protein.
Length = 1454
Score = 52.8 bits (121), Expect = 3e-06
Identities = 106/498 (21%), Positives = 204/498 (40%), Gaps = 41/498 (8%)
Query: 52 AELKND--EINSMIRQLXXXXXXXXXXXXXLTEKLT-IAETKHNDLKKLYEDSASELEAL 108
AEL+ + E N IR L EK I +H +++K E ++LE
Sbjct: 602 AELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKK 661
Query: 109 KRE------NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLK--KNSITK 160
++ + M D++ ++SL ++ T + G E + + LK +N +++
Sbjct: 662 DQQFKEQEKTMSMLQQDIICKQHHLESLDRLL-TESKGEMKKENMKKDEALKALQNQVSE 720
Query: 161 DNISIKTLLDKL-ITKNET--DINELR-NSIKYLESVK--SEYNTANEKLFEQLNNAVDK 214
+ I ++ L L I K E +N+L N K+ + +K SE +K + N+++ +
Sbjct: 721 ETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQE 780
Query: 215 ---QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
QN I + L+ + Q L Q K L++ + E K
Sbjct: 781 TSEQNVILQHT--LQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAE-K 837
Query: 272 LSEIKEKDENFKQEIDMLNEKLI---CDRREFNETMQEKNILLSDLSKKVNKTERELEEK 328
L +++EK E+ E D+ +K+I R+ M + LS + K++ +R+ E K
Sbjct: 838 LRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENK 897
Query: 329 QEQLTHLMEQLNDTENNSYKLIENMFNKVSQI--ASDFKISNQLSCE--LDDESENTYER 384
L+ L L+ T+ K N ++ ++ +++ +++ L L+ E +N +
Sbjct: 898 AMHLSQLDMILDQTKTELEKK-TNAVKELEKLQHSTETELTEALQKREVLETELQNAHGE 956
Query: 385 ISLTLDKITN-----HITYLNTQINETQKNDNAQLLWEAKKQIAD----LTEQNIILKER 435
+ TL ++ L+ + T D L E K +I D L E + LKER
Sbjct: 957 LKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDKKQELLEMDQALKER 1016
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
+L+ ++ T+R E+ + + +IE + K+
Sbjct: 1017 NWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNA 1076
Query: 496 KSQFEDLDDVMKQQQKEL 513
K Q + + +M Q ++E+
Sbjct: 1077 KEQLREKEFIMLQNEQEI 1094
Score = 50.0 bits (114), Expect = 2e-05
Identities = 84/505 (16%), Positives = 202/505 (40%), Gaps = 24/505 (4%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETK 90
+E +L S + V +G V +K+ ++M +Q L KL E +
Sbjct: 478 QESSKLSSLETEPVKLGGHQVESVKDQNQHTMNKQYEKERQRLVTGIEELRTKLIQIEAE 537
Query: 91 HNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALE 150
++DLK S+ + ++ E ++ ++ + E+ ++++ TL E
Sbjct: 538 NSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLL-TLEKQLEEKIVAYSS 596
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN 210
I K + ++ + + L T T+ ++ + + + + E + EK E+L
Sbjct: 597 IAAKNAELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEA 656
Query: 211 AVDK--QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML- 267
++K Q ++E + ++ + + + + + E +K +
Sbjct: 657 QLEKKDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQN 716
Query: 268 -VEEKLSEIKEKD---ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
V E+ ++++ D E K+E+ + +L ++ +F + +++K+ + L K++
Sbjct: 717 QVSEETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNH 776
Query: 324 ELEEKQEQ---LTHLMEQLNDT------ENNSYKLIENMFNK-VSQIASDFKISNQLSCE 373
L+E EQ L H ++Q N + + K VS++ + + + S E
Sbjct: 777 SLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAE 836
Query: 374 ----LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQN 429
++++ E+ L K+ +T Q+ + + + + L + +K+I L
Sbjct: 837 KLRKMEEKCESAAHEADLKRQKVIE-LTGTARQV-KIEMDQYKEELSKMEKEIMHLKRDG 894
Query: 430 IILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
LSQL+ + E++ + +E+ + T E+++
Sbjct: 895 ENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAH 954
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELK 514
++ Q ++L DV+++ Q L+
Sbjct: 955 GELKSTLRQLQELRDVLQKAQLSLE 979
Score = 42.7 bits (96), Expect = 0.003
Identities = 75/425 (17%), Positives = 183/425 (43%), Gaps = 34/425 (8%)
Query: 104 ELEALKR--ENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKD 161
E+ LKR EN MH S + + I+D + TN + LE++ + + +
Sbjct: 886 EIMHLKRDGENKAMHLSQLDM---ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQK 942
Query: 162 NISIKTLLDKL---ITKNETDINELRNSIKYLE-SVKSEYNTANE---KLFEQLNNAVDK 214
++T L + + ELR+ ++ + S++ +Y T + +L E DK
Sbjct: 943 REVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDK 1002
Query: 215 QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSE 274
+ + E LK N L Q ++ I LE T+ EK SE
Sbjct: 1003 KQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEG--TL---EK-SE 1056
Query: 275 IKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTH 334
++ K+ N ++I+ LN+KL + E ++EK ++ +++++ ++E+E Q+++
Sbjct: 1057 LELKECN--KQIESLNDKL----QNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKE 1110
Query: 335 LMEQLNDTENNSYKLIENMFNKVSQIASDFKIS-NQLSCELDDESENTYERISL--TLDK 391
+ + + E + I + + + + +++ Q+ + +E ++++ +++
Sbjct: 1111 MESVMKEQE----QYIATQYKEAIDLGQELRLTREQVQNSHTELAEARHQQVQAQREIER 1166
Query: 392 ITNHITYLNTQINETQKNDN--AQLLWEAKKQIADL-TEQNIILKERLSQLETENKELLI 448
+++ + + E + N A+ L +K + A L +K+ +++E+ + +
Sbjct: 1167 LSSELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHM 1226
Query: 449 EIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQ 508
E+ + + ++ + ++ + E+E+ + V Q +D ++V++
Sbjct: 1227 EMISHQENHAKWKISADSQKSSVQQLNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEA 1286
Query: 509 QQKEL 513
+ L
Sbjct: 1287 ANEAL 1291
Score = 41.9 bits (94), Expect = 0.005
Identities = 42/191 (21%), Positives = 91/191 (47%), Gaps = 15/191 (7%)
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
LE+ + M++E++ S + K+E K ++D+L + R E E +LSK
Sbjct: 196 LEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAE--RQRNEALYNAEELSKAFQ 253
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE 379
+ ++++ EK E++ E L N K + + + S+ +I + +L +E+
Sbjct: 254 QYKKKVAEKLEKVQAEEEILERNLTNCEKENKRLQERCGLYKSELEILKEKLRQLKEENN 313
Query: 380 NTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL 439
N E++ + K N+++ Q ++ Q + + + ++ + E IL+++ S L
Sbjct: 314 NGKEKLRIMAVK--------NSEV-MAQLTESRQSILKLESELENKDE---ILRDKFS-L 360
Query: 440 ETENKELLIEI 450
EN+EL + +
Sbjct: 361 MNENRELKVRV 371
Score = 36.7 bits (81), Expect = 0.20
Identities = 71/346 (20%), Positives = 140/346 (40%), Gaps = 28/346 (8%)
Query: 23 KIRLEECYKEIGQLKSGLQQ-NVGVGDKTVAELKND-EINSMIRQLXXXXXXXXXXXXXL 80
++ L+EC K+I L LQ + +K L+N+ EI+ + +++ +
Sbjct: 1056 ELELKECNKQIESLNDKLQNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKEMESVM 1115
Query: 81 TEKLTIAETKHNDLKKLYEDSASELEALKRENIQ-MHTSDVMVVPEIIDSLTEVINTLTN 139
E+ T++ + D EL L RE +Q HT + + + E I L++
Sbjct: 1116 KEQEQYIATQYKEAI----DLGQELR-LTREQVQNSHTELAEARHQQVQAQRE-IERLSS 1169
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIK------YLESV 193
E +++++ E D N + ++ + K L + + +I +L ++ ++E +
Sbjct: 1170 ELEDMKQLSKEKDAHGNHLAEELGASKVREAHLEARMQAEIKKLSAEVESLKEAYHMEMI 1229
Query: 194 KSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXAR 253
+ N A K+ + +Q + E+++ K+E + A
Sbjct: 1230 SHQENHAKWKISADSQKSSVQQ--LNEQLEKAKLELEEAQDTVSNLHQQVQDRNEVIEAA 1287
Query: 254 DKFIANLEEMKTMLV-----EEKLSEIKEKDENFKQ--EI--DMLNEKLI-CDRREFNE- 302
++ + E T L EK +IK F EI D+ + K C F++
Sbjct: 1288 NEALLTKESELTRLQAKISGHEKAEDIKFLPAPFTSPTEIMPDVQDPKFAKCFHTSFSKC 1347
Query: 303 TMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
T ++I SDL+ K++ E EE + L + + T S+K
Sbjct: 1348 TKLRRSISASDLTFKIHGDEDLSEELLQDLKKMQLEQPSTLEESHK 1393
Score = 35.5 bits (78), Expect = 0.46
Identities = 34/160 (21%), Positives = 71/160 (44%), Gaps = 8/160 (5%)
Query: 311 LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQL 370
+S K + + E +LE+ Q+ + + L +++ KL ++ + Q + N+
Sbjct: 182 VSAQDKVLREAENKLEQSQKMVIEKEQSLQESKEECIKLKVDLLEQTKQGKRAERQRNEA 241
Query: 371 ---SCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE 427
+ EL + ++++ L+K+ L + +K +N +L ++L
Sbjct: 242 LYNAEELSKAFQQYKKKVAEKLEKVQAEEEILERNLTNCEK-ENKRLQERCGLYKSELE- 299
Query: 428 QNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS 467
ILKE+L QL+ EN +++ + N EV L +S
Sbjct: 300 ---ILKEKLRQLKEENNNGKEKLRIMAVKNSEVMAQLTES 336
>AL139095-7|CAI16451.1| 847|Homo sapiens cancer antigen 1 protein.
Length = 847
Score = 52.8 bits (121), Expect = 3e-06
Identities = 47/217 (21%), Positives = 104/217 (47%), Gaps = 12/217 (5%)
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
K + NLEE+ ++ L E + E + + + +C + + MQ+KN +S
Sbjct: 410 KTLQNLEEVLAN-TQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQY 468
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ ++KT + EE+ E+L L ++L ++ L++ K +Q + + +L
Sbjct: 469 LE-MDKTLSKKEEEVERLQQLKKELEKATASALDLLKR--EKEAQEQEFLSLQEEFQ-KL 524
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ E+ +++ L+K+ + L ++E ++ N +L ++QI ++ +N LK+
Sbjct: 525 EKENLEERQKLKSRLEKLLTQVRNLQF-MSENERTKNIKL----QQQINEVKNENAKLKQ 579
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLN--LKDSST 469
++++ E +N E ++ EEV + KD+ T
Sbjct: 580 QVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKT 616
Score = 39.5 bits (88), Expect = 0.028
Identities = 42/213 (19%), Positives = 89/213 (41%), Gaps = 13/213 (6%)
Query: 132 EVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLE 191
+VIN L E L E +I L+KN TK + L++++ + + E RN + L+
Sbjct: 382 DVINKLKENVEELIEDKYKIILEKND-TKKTLQ---NLEEVLANTQKHLQESRNDKEMLQ 437
Query: 192 ----SVKSEYNTANEKLFEQL--NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
+K+ Y E+ ++ N Q ++ K E LQ
Sbjct: 438 LQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATA 497
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQ 305
R+K +E + + ++E+ ++++++ +Q++ EKL+ R +
Sbjct: 498 SALDLLKREK---EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSE 554
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ L +++N+ + E + ++Q+ EQ
Sbjct: 555 NERTKNIKLQQQINEVKNENAKLKQQVARSEEQ 587
Score = 38.3 bits (85), Expect = 0.065
Identities = 31/158 (19%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
+DK ++K E ++ L+ K LE TA+ + +Q + + + K+E
Sbjct: 471 MDKTLSKKEEEVERLQQLKKELEKA-----TASALDLLKREKEAQEQEFLSLQEEFQKLE 525
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDM 288
+NL + + F++ E K + ++++++E+K ++ KQ++
Sbjct: 526 KENLEERQKLKSRLEKLLTQVRNLQ--FMSENERTKNIKLQQQINEVKNENAKLKQQVAR 583
Query: 289 LNEKLICDRREFNETM-QEKNILLSDLSKKVNKTEREL 325
E+ + E + Q + +L SD++K T L
Sbjct: 584 SEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNL 621
Score = 37.9 bits (84), Expect = 0.085
Identities = 50/254 (19%), Positives = 91/254 (35%), Gaps = 9/254 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+M V +KL K E QE+ N L +E + ++ + + +NK
Sbjct: 331 EDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFID----VINK 386
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
+ +EE E ++ + NDT+ L E + N + L + N
Sbjct: 387 LKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKAN 446
Query: 381 ---TYERISLTLDKITNHIT-YLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
ER + + ++ YL ++K + + L + KK++ T + +LK
Sbjct: 447 YVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKRE 506
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
E E L E Q + N E LK S K+ +
Sbjct: 507 KEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQ 566
Query: 496 KSQFEDLDDVMKQQ 509
++ ++ + +KQQ
Sbjct: 567 INEVKNENAKLKQQ 580
>AL139095-5|CAI16449.1| 545|Homo sapiens cancer antigen 1 protein.
Length = 545
Score = 52.8 bits (121), Expect = 3e-06
Identities = 47/217 (21%), Positives = 104/217 (47%), Gaps = 12/217 (5%)
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
K + NLEE+ ++ L E + E + + + +C + + MQ+KN +S
Sbjct: 108 KTLQNLEEVLAN-TQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQY 166
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ ++KT + EE+ E+L L ++L ++ L++ K +Q + + +L
Sbjct: 167 LE-MDKTLSKKEEEVERLQQLKKELEKATASALDLLKR--EKEAQEQEFLSLQEEFQ-KL 222
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ E+ +++ L+K+ + L ++E ++ N +L ++QI ++ +N LK+
Sbjct: 223 EKENLEERQKLKSRLEKLLTQVRNLQF-MSENERTKNIKL----QQQINEVKNENAKLKQ 277
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLN--LKDSST 469
++++ E +N E ++ EEV + KD+ T
Sbjct: 278 QVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKT 314
Score = 39.5 bits (88), Expect = 0.028
Identities = 42/213 (19%), Positives = 89/213 (41%), Gaps = 13/213 (6%)
Query: 132 EVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLE 191
+VIN L E L E +I L+KN TK + L++++ + + E RN + L+
Sbjct: 80 DVINKLKENVEELIEDKYKIILEKND-TKKTLQ---NLEEVLANTQKHLQESRNDKEMLQ 135
Query: 192 ----SVKSEYNTANEKLFEQL--NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
+K+ Y E+ ++ N Q ++ K E LQ
Sbjct: 136 LQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATA 195
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQ 305
R+K +E + + ++E+ ++++++ +Q++ EKL+ R +
Sbjct: 196 SALDLLKREK---EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSE 252
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ L +++N+ + E + ++Q+ EQ
Sbjct: 253 NERTKNIKLQQQINEVKNENAKLKQQVARSEEQ 285
Score = 38.3 bits (85), Expect = 0.065
Identities = 31/158 (19%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
+DK ++K E ++ L+ K LE TA+ + +Q + + + K+E
Sbjct: 169 MDKTLSKKEEEVERLQQLKKELEKA-----TASALDLLKREKEAQEQEFLSLQEEFQKLE 223
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDM 288
+NL + + F++ E K + ++++++E+K ++ KQ++
Sbjct: 224 KENLEERQKLKSRLEKLLTQVRNLQ--FMSENERTKNIKLQQQINEVKNENAKLKQQVAR 281
Query: 289 LNEKLICDRREFNETM-QEKNILLSDLSKKVNKTEREL 325
E+ + E + Q + +L SD++K T L
Sbjct: 282 SEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNL 319
Score = 37.9 bits (84), Expect = 0.085
Identities = 50/254 (19%), Positives = 91/254 (35%), Gaps = 9/254 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+M V +KL K E QE+ N L +E + ++ + + +NK
Sbjct: 29 EDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFID----VINK 84
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
+ +EE E ++ + NDT+ L E + N + L + N
Sbjct: 85 LKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKAN 144
Query: 381 ---TYERISLTLDKITNHIT-YLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
ER + + ++ YL ++K + + L + KK++ T + +LK
Sbjct: 145 YVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKRE 204
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
E E L E Q + N E LK S K+ +
Sbjct: 205 KEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQ 264
Query: 496 KSQFEDLDDVMKQQ 509
++ ++ + +KQQ
Sbjct: 265 INEVKNENAKLKQQ 278
>AK097760-1|BAC05162.1| 824|Homo sapiens protein ( Homo sapiens
cDNA FLJ40441 fis, clone TESTI2040094. ).
Length = 824
Score = 52.8 bits (121), Expect = 3e-06
Identities = 47/217 (21%), Positives = 104/217 (47%), Gaps = 12/217 (5%)
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
K + NLEE+ ++ L E + E + + + +C + + MQ+KN +S
Sbjct: 380 KTLQNLEEVLAN-TQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQY 438
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ ++KT + EE+ E+L L ++L ++ L++ K +Q + + +L
Sbjct: 439 LE-MDKTLSKKEEEVERLQQLKKELEKATASALDLLKR--EKEAQEQEFLSLQEEFQ-KL 494
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ E+ +++ L+K+ + L ++E ++ N +L ++QI ++ +N LK+
Sbjct: 495 EKENLEERQKLKSRLEKLLTQVRNLQF-MSENERTKNIKL----QQQINEVKNENAKLKQ 549
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLN--LKDSST 469
++++ E +N E ++ EEV + KD+ T
Sbjct: 550 QVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKT 586
Score = 39.5 bits (88), Expect = 0.028
Identities = 42/213 (19%), Positives = 89/213 (41%), Gaps = 13/213 (6%)
Query: 132 EVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLE 191
+VIN L E L E +I L+KN TK + L++++ + + E RN + L+
Sbjct: 352 DVINKLKENVEELIEDKYKIILEKND-TKKTLQ---NLEEVLANTQKHLQESRNDKEMLQ 407
Query: 192 ----SVKSEYNTANEKLFEQL--NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
+K+ Y E+ ++ N Q ++ K E LQ
Sbjct: 408 LQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATA 467
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQ 305
R+K +E + + ++E+ ++++++ +Q++ EKL+ R +
Sbjct: 468 SALDLLKREK---EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSE 524
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ L +++N+ + E + ++Q+ EQ
Sbjct: 525 NERTKNIKLQQQINEVKNENAKLKQQVARSEEQ 557
Score = 38.3 bits (85), Expect = 0.065
Identities = 31/158 (19%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
+DK ++K E ++ L+ K LE TA+ + +Q + + + K+E
Sbjct: 441 MDKTLSKKEEEVERLQQLKKELEKA-----TASALDLLKREKEAQEQEFLSLQEEFQKLE 495
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDM 288
+NL + + F++ E K + ++++++E+K ++ KQ++
Sbjct: 496 KENLEERQKLKSRLEKLLTQVRNLQ--FMSENERTKNIKLQQQINEVKNENAKLKQQVAR 553
Query: 289 LNEKLICDRREFNETM-QEKNILLSDLSKKVNKTEREL 325
E+ + E + Q + +L SD++K T L
Sbjct: 554 SEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNL 591
Score = 37.9 bits (84), Expect = 0.085
Identities = 50/254 (19%), Positives = 91/254 (35%), Gaps = 9/254 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+M V +KL K E QE+ N L +E + ++ + + +NK
Sbjct: 301 EDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFID----VINK 356
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
+ +EE E ++ + NDT+ L E + N + L + N
Sbjct: 357 LKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKAN 416
Query: 381 ---TYERISLTLDKITNHIT-YLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
ER + + ++ YL ++K + + L + KK++ T + +LK
Sbjct: 417 YVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKRE 476
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
E E L E Q + N E LK S K+ +
Sbjct: 477 KEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQ 536
Query: 496 KSQFEDLDDVMKQQ 509
++ ++ + +KQQ
Sbjct: 537 INEVKNENAKLKQQ 550
>AF414185-1|AAO47239.1| 641|Homo sapiens CAGE-1 protein.
Length = 641
Score = 52.8 bits (121), Expect = 3e-06
Identities = 47/217 (21%), Positives = 104/217 (47%), Gaps = 12/217 (5%)
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
K + NLEE+ ++ L E + E + + + +C + + MQ+KN +S
Sbjct: 244 KTLQNLEEVLAN-TQKHLQESRNDKEMLQLQFKKIKANYVCLQERYMTEMQQKNKSVSQY 302
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ ++KT + EE+ E+L L ++L ++ L++ K +Q + + +L
Sbjct: 303 LE-MDKTLSKKEEEVERLQQLKKELEKATASALDLLKR--EKEAQEQEFLSLQEEFQ-KL 358
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+ E+ +++ L+K+ + L ++E ++ N +L ++QI ++ +N LK+
Sbjct: 359 EKENLEERQKLKSRLEKLLTQVRNLQF-MSENERTKNIKL----QQQINEVKNENAKLKQ 413
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLN--LKDSST 469
++++ E +N E ++ EEV + KD+ T
Sbjct: 414 QVARSEEQNYVPKFETAQLKDQLEEVLKSDITKDTKT 450
Score = 39.5 bits (88), Expect = 0.028
Identities = 42/213 (19%), Positives = 89/213 (41%), Gaps = 13/213 (6%)
Query: 132 EVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLE 191
+VIN L E L E +I L+KN TK + L++++ + + E RN + L+
Sbjct: 216 DVINKLKENVEELIEDKYKIILEKND-TKKTLQ---NLEEVLANTQKHLQESRNDKEMLQ 271
Query: 192 ----SVKSEYNTANEKLFEQL--NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
+K+ Y E+ ++ N Q ++ K E LQ
Sbjct: 272 LQFKKIKANYVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATA 331
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQ 305
R+K +E + + ++E+ ++++++ +Q++ EKL+ R +
Sbjct: 332 SALDLLKREK---EAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSE 388
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+ L +++N+ + E + ++Q+ EQ
Sbjct: 389 NERTKNIKLQQQINEVKNENAKLKQQVARSEEQ 421
Score = 38.3 bits (85), Expect = 0.065
Identities = 31/158 (19%), Positives = 68/158 (43%), Gaps = 8/158 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
+DK ++K E ++ L+ K LE TA+ + +Q + + + K+E
Sbjct: 305 MDKTLSKKEEEVERLQQLKKELEKA-----TASALDLLKREKEAQEQEFLSLQEEFQKLE 359
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDM 288
+NL + + F++ E K + ++++++E+K ++ KQ++
Sbjct: 360 KENLEERQKLKSRLEKLLTQVRNLQ--FMSENERTKNIKLQQQINEVKNENAKLKQQVAR 417
Query: 289 LNEKLICDRREFNETM-QEKNILLSDLSKKVNKTEREL 325
E+ + E + Q + +L SD++K T L
Sbjct: 418 SEEQNYVPKFETAQLKDQLEEVLKSDITKDTKTTHSNL 455
Score = 37.9 bits (84), Expect = 0.085
Identities = 50/254 (19%), Positives = 91/254 (35%), Gaps = 9/254 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+M V +KL K E QE+ N L +E + ++ + + +NK
Sbjct: 165 EDMALNEVLQKLKHTNRKQEVRIQELQCSNLYLEKRVKELQMKITKQQVFID----VINK 220
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
+ +EE E ++ + NDT+ L E + N + L + N
Sbjct: 221 LKENVEELIEDKYKIILEKNDTKKTLQNLEEVLANTQKHLQESRNDKEMLQLQFKKIKAN 280
Query: 381 ---TYERISLTLDKITNHIT-YLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
ER + + ++ YL ++K + + L + KK++ T + +LK
Sbjct: 281 YVCLQERYMTEMQQKNKSVSQYLEMDKTLSKKEEEVERLQQLKKELEKATASALDLLKRE 340
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
E E L E Q + N E LK S K+ +
Sbjct: 341 KEAQEQEFLSLQEEFQKLEKENLEERQKLKSRLEKLLTQVRNLQFMSENERTKNIKLQQQ 400
Query: 496 KSQFEDLDDVMKQQ 509
++ ++ + +KQQ
Sbjct: 401 INEVKNENAKLKQQ 414
>AF272390-1|AAF78783.1| 1742|Homo sapiens myosin 5c protein.
Length = 1742
Score = 52.8 bits (121), Expect = 3e-06
Identities = 75/399 (18%), Positives = 173/399 (43%), Gaps = 26/399 (6%)
Query: 126 IIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRN 185
+++ LT + E +++ LE +L+K + + N K + E + +L+
Sbjct: 908 LVEKLTSLAALRAGDVEKIQK--LEAELEKAATHRRNYEEKG--KRYRDAVEEKLAKLQK 963
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
LE+ K + ++ E+L +D Q D+ K E Q +L
Sbjct: 964 HNSELETQKEQIQLKLQEKTEELKEKMDNLTK-QLFDDVQKEERQRMLLEKSFELKTQDY 1022
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE--KLICDRREFNET 303
+++ A +E M ++ + + K E+ L++ K I + + E
Sbjct: 1023 EKQIQSLKEEIKALKDEK--MQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIEL 1080
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKL-IENM--FNKVSQI 360
+Q + I D+ K V +RE+ EK ++T + + D E+ +L +E++ N+ ++
Sbjct: 1081 LQAQKI---DVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGEL 1137
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQK--NDNAQLLWEA 418
++ + + L+ ++ + ++ + + +L+ +IN QK + +
Sbjct: 1138 WFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREENDINESI 1197
Query: 419 KKQIADLTEQNIIL---KERLSQLETENKELLIEI----QTVRGSNEEVTLNLKDSSTXX 471
+ ++ LT +N+++ K+++S+LE + ++L I + + ++G EE++ N S
Sbjct: 1198 RHEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELS-NQLHRSQEE 1256
Query: 472 XXXXXXXXXXSNEIEDM-KTKVMEWKSQFEDLDDVMKQQ 509
NEI K K+++ + ++ D +K+Q
Sbjct: 1257 EGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQ 1295
Score = 35.1 bits (77), Expect = 0.60
Identities = 26/111 (23%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E N L + E+ ++ +AL+ +N ++HT + + + I + E + L FE+ EV
Sbjct: 1244 EELSNQLHRSQEEEGTQRKALEAQN-EIHTKEKEKLIDKIQEMQEASDHLKKQFETESEV 1302
Query: 148 ALEIDLKKNSITKDNISIKTLL---DKLITKNETDINELRNSIKYLESVKS 195
+ + +T +N ++ L D++I K + + L +I V S
Sbjct: 1303 KCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHS 1353
>L40157-1|AAA79121.1| 1410|Homo sapiens endosome-associated protein
protein.
Length = 1410
Score = 52.4 bits (120), Expect = 4e-06
Identities = 92/462 (19%), Positives = 197/462 (42%), Gaps = 37/462 (8%)
Query: 27 EECYKE---IGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEK 83
EE KE I LK+ L Q G+ D V + + ++ +++ + ++K
Sbjct: 198 EELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDESKK 257
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
E+++ + SEL +E ++++ ++ + ++ LT+ TLT
Sbjct: 258 F---ESQYASSEATISQLRSELSKGPQE-VRVYVQELQKLKSSVNELTQKNQTLTENLLK 313
Query: 144 LEEVALEIDLKKN--SITKDNISIKTLLDKLI--TKNETDINELRNSIKYLESVKSEYNT 199
E+ +++ K N S++K NI TL K + + ++ ++ S+ + SE
Sbjct: 314 KEQDYTKLEEKHNEESVSKKNIQ-ATLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGE 372
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
A +KL E+L+ K ++ E L+ + + Q ++
Sbjct: 373 ATQKLKEELSEVETKYQHLKAEFKQLQQQREEKEQHGLQLQSEINQLHSKLLETER---Q 429
Query: 260 LEEMKTMLVEEK-LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
L E L E++ LS K D+ +Q++ L KL E ++EK ++L ++
Sbjct: 430 LGEAHGRLKEQRQLSSEKLMDK--EQQVADLQLKL----SRLEEQLKEKVTNSTELQHQL 483
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENM---FNKVSQIASDFKISNQLSCELD 375
+KT+++ +E+Q +L + +N+ +++ + K+ + + + S + L+
Sbjct: 484 DKTKQQHQEQQALQQSTTAKLREAQNDLEQVLRQIGEKDQKIQNLEALLQKSKENISLLE 543
Query: 376 DESENTYERISLTLDK--ITNHITYLNTQINE--TQKNDNAQLLWEAKKQIAD-----LT 426
E E+ Y +I + + N + N + + TQ +N + E+ KQ + +
Sbjct: 544 KEREDLYAKIQAGEGETAVLNQLQEKNHTLQDEVTQLTENVKNQSESHKQAQENLHDQVQ 603
Query: 427 EQNIILK---ERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
EQ L+ +R+ LET EL ++ + ++ + +K
Sbjct: 604 EQKAHLRAAQDRVLSLETSVNELNSQLNESKEKVSQLDIQIK 645
Score = 49.2 bits (112), Expect = 3e-05
Identities = 77/408 (18%), Positives = 172/408 (42%), Gaps = 26/408 (6%)
Query: 53 ELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKREN 112
+++++E+N+ I+ L +L+ + K + + ++S SE E ++
Sbjct: 824 KIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKG 883
Query: 113 IQMHTSDVMVVPEIIDSL-TEVINTLTNGFE---SLE---EVALEIDLKKNSITKDNISI 165
E+ L ++ NTL E SLE E + ++ L+ NS+ + I
Sbjct: 884 KAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQA 943
Query: 166 KTLL---DKLITKNETDINELRNSI----KYLESVKSEYNTA-------NEKLFEQLNNA 211
+ L +K + + +INEL+ S K +E+++ E A KL +QL A
Sbjct: 944 QNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQA 1003
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +E++ +L+ + + A + + ++EE ++ E+
Sbjct: 1004 AQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDL 1063
Query: 272 LSEIKEKDENFK--QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
+S + K QE+ L D + + +QE+ L D+ K+ + E+EL ++
Sbjct: 1064 ISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEK 1123
Query: 330 EQLTHLMEQLNDTENNSYKLIENM-FNKVSQI--ASDFKISNQLSCELDDESENTYERIS 386
+L + E E KL E + +K+ I ++ K + QL + E + + +
Sbjct: 1124 SKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLK 1183
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+++ + L Q+ + ++ + + + K +++ E+ + +K+
Sbjct: 1184 AAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKK 1231
Score = 48.0 bits (109), Expect = 8e-05
Identities = 74/415 (17%), Positives = 171/415 (41%), Gaps = 36/415 (8%)
Query: 101 SASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITK 160
SA + +R ++Q H + + +N +T L++V ++ K+ ++
Sbjct: 653 SAEAAKTAQRADLQNHLDTAQ---NALQDKHQELNKITT---QLDQVTAKLQDKQEHCSQ 706
Query: 161 DNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQE 220
+K +K ++ E EL IK LE+ E + E+ + L +Q +
Sbjct: 707 LESHLKEYKEKYLSL-EQKTEELEGQIKKLEADSLEVKASKEQALQDLQ----QQRQLNT 761
Query: 221 EVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDE 280
+++L E L+ K LE +K +KL++ +E+ +
Sbjct: 762 DLELRATELSKQLEMEKEIVSSTRLDL------QKKSEALESIK-----QKLTKQEEEKQ 810
Query: 281 NFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLN 340
KQ+ + L+++ E N +Q L + + EL +++L+ + + L
Sbjct: 811 ILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLK 870
Query: 341 DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENT---YERISLTLDKITNHIT 397
++++ K EN K + + + K +L +L + ENT + + +L+K
Sbjct: 871 NSKSEFEK--ENQKGKAAILDLE-KTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASH 927
Query: 398 YLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSN 457
L ++N Q+ QL+ +A+ + ++ L+ +++L+ +++ +I+ ++G
Sbjct: 928 QLKLELNSMQE----QLI-QAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQG-- 980
Query: 458 EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
E+ + + + + E+ K K+ ++ +E + KQ Q +
Sbjct: 981 -ELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSD 1034
>BX538286-1|CAD98081.1| 724|Homo sapiens hypothetical protein
protein.
Length = 724
Score = 52.4 bits (120), Expect = 4e-06
Identities = 91/517 (17%), Positives = 219/517 (42%), Gaps = 44/517 (8%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAE-LKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAET 89
+E +L S + V +G VAE +K+ ++M +Q L KL E
Sbjct: 198 QESSKLSSLETEPVKLGGHQVAESVKDQNQHTMNKQYEKERQGLVTGIEELRTKLIQIEA 257
Query: 90 KHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVAL 149
+++DLK S+ + ++ E ++ ++ + E+ ++++ TL E + VA
Sbjct: 258 ENSDLKVNMAHRTSQFQLIQEELLEKASNSSKLESEMTKKCSQLL-TLEKQLEE-KIVAY 315
Query: 150 EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLES---VKSEYNTANEKLFE 206
KN+ + + ++ L+K + E ++ L+ K + + ++L
Sbjct: 316 SSIAAKNAELEQELMLEAQLEK----KDQQFKEQEKTMSMLQQDIICKQHHLESLDRLLT 371
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQ---NLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
+ + K+N ++E L ++NQ ++ ++ N E+
Sbjct: 372 ESKGEMKKENMKKDEA-LKALQNQVSEETIKVRQLDSALEIRKEELVLHLNQLEGNKEKF 430
Query: 264 KTMLVEEK------LSEIKEKDENFKQ--EIDMLNEKLICDRREFNETMQEKNILLSD-- 313
+ L ++ E+K K+ + ++ E +++ + + +++ + +N L D
Sbjct: 431 EKQLKKKSEEVYCLQKELKIKNHSLQETSEQNVILQHTLQQQQQMLQQETIRNGELEDTQ 490
Query: 314 --LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
L K+V+K E+EL++++E + ++ + ++ + KV ++ + Q+
Sbjct: 491 TKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAAHEADLKRQKVIELTGT---ARQVK 547
Query: 372 CELDDESE--NTYERISLTL----DKITNHITYLNTQINET----QKNDNA-----QLLW 416
E+D E + E+ + L + H++ L+ +++T +K NA +L
Sbjct: 548 IEMDQYKEELSKMEKEIMHLKRDGENKAMHLSQLDMILDQTKTELEKKTNAVKELEKLQH 607
Query: 417 EAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXX 476
+ ++ + ++ +L+ L E K L ++Q +R ++ L+L++ T
Sbjct: 608 STETELTEALQKREVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTA 667
Query: 477 XXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
EIED K +++E ++ + +KQ+ ++
Sbjct: 668 ELRECKMEIEDKKQELLEMDQALKERNWELKQRAAQV 704
>AB019691-1|BAA78718.1| 3899|Homo sapiens Centrosome- and
Golgi-localized PKN-associated protein (CG-NAP) protein.
Length = 3899
Score = 52.4 bits (120), Expect = 4e-06
Identities = 93/394 (23%), Positives = 179/394 (45%), Gaps = 53/394 (13%)
Query: 93 DLKKLYEDSASE----LEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVA 148
+L KL ED E +E LK +N+ +H + ID L N ++ E+++
Sbjct: 636 ELSKLKEDLEIEHRISIEKLK-DNLGIHYK------QQIDGLQ---NEMSQKIETMQFEK 685
Query: 149 LEIDLKKNSITKDNISIKTLLDKLI-TKNET---DINELRNSIKYLESVKSEYNTANEKL 204
+ K+N + + +K L L+ +K+E INEL+ I+ L + E T +++
Sbjct: 686 DNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEV 745
Query: 205 FE-QLNNAV------DKQNCIQEEVDLLKIENQNLL-QXXXXXXXXXXXXXXXXXARDKF 256
E QL + +K+N +QE+ L+ EN L + R F
Sbjct: 746 QELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIF 805
Query: 257 IANLEEMKTMLVEEKLSEIK-EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
+ +++ V EK EI E++E+ KQ+ LNE++ R F + EKN
Sbjct: 806 LDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTF--SFAEKNF------ 857
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTENN---SYKLIENMFNKVSQIASDFKISNQLSC 372
+VN +EL+E+ L + + L D++N YK N+ + + ++
Sbjct: 858 -EVN--YQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELNLQRINPTTVKMKS 914
Query: 373 ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL 432
+ DE + T+ +L + ++ T T++ E + + L E ++++DL+EQ L
Sbjct: 915 SVFDE-DKTFVAETLEMGEVVEKDT---TELMENLEVTKREKL-ELSQRLSDLSEQ---L 966
Query: 433 KERLSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
K++ ++ N+ E+++++ E+V+L ++
Sbjct: 967 KQKHGEISFLNE----EVKSLKQEKEQVSLRCRE 996
Score = 49.6 bits (113), Expect = 3e-05
Identities = 72/307 (23%), Positives = 138/307 (44%), Gaps = 26/307 (8%)
Query: 173 ITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL 232
IT NE I + +I L + N+ EKL E+L ++++ +Q +++ L E
Sbjct: 481 ITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFS 540
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLV--EEKLSEIKEKDE----NFKQEI 286
K ++ +E++K +V E E++ K E N+K ++
Sbjct: 541 RGQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 600
Query: 287 DMLNEK--LICDR-REFNETMQEK---NILLS---DLSKKVNKTERE----LEEKQEQL- 332
+ML ++ + DR E E E+ +L S +LSK E E +E+ ++ L
Sbjct: 601 EMLEKEKNAVLDRMAESQEAELERLSTQLLFSHEEELSKLKEDLEIEHRISIEKLKDNLG 660
Query: 333 THLMEQLNDTENNSYKLIENM-FNKVSQIASDFKISNQLS--CELDDESENT-YERISLT 388
H +Q++ +N + IE M F K + I ++ ++S +L N+ E ++L
Sbjct: 661 IHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ 720
Query: 389 LDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++++ I L + E T + + +L + + + E+ L+E+ +QLE EN L
Sbjct: 721 INELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSIL 780
Query: 447 LIEIQTV 453
E +T+
Sbjct: 781 KDEKKTL 787
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/190 (19%), Positives = 95/190 (50%), Gaps = 15/190 (7%)
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQE 330
+L E++++++ FK +++ L + + + Q++++L ++ + + E E+++ E
Sbjct: 2235 RLQELEQENKLFKDDMEKLG---LAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNE 2291
Query: 331 QLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK-ISNQLSCELDDESENTYERISLTL 389
Q+T L +QL T +N K+IE + + + + + + C + E E+++ +
Sbjct: 2292 QVTKLQQQLKITTDN--KVIEEKNELIRDLETQIECLMSDQEC-VKRNREEEIEQLNEVI 2348
Query: 390 DKITNHITYL--NTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
+K+ + + T +N ++ A L K Q+ + + + L++ Q+ET N+E+
Sbjct: 2349 EKLQQELANIGQKTSMNAHSLSEEADSL---KHQLDVVIAEKLALEQ---QVETANEEMT 2402
Query: 448 IEIQTVRGSN 457
++ +N
Sbjct: 2403 FMKNVLKETN 2412
Score = 44.8 bits (101), Expect = 7e-04
Identities = 56/335 (16%), Positives = 145/335 (43%), Gaps = 22/335 (6%)
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
LE + E+ K++ I + N ++ + T+ + E +IK + + ++ ++
Sbjct: 157 LEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQ 216
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNL-LQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ + + + + E+ L+I+ Q L A+ + + + ++
Sbjct: 217 ARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQ 276
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC-----DRREFN---ETMQEKNILLSDL 314
++ + L + ++K E+F +I L EK+ D++ N E +QEK ++ +L
Sbjct: 277 LEEQ--DHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 334
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ K+ + E++ E +++LT + L + + + + + N ++ + + Q S E+
Sbjct: 335 NTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEI 394
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII--- 431
+ T E L K + + T I + + + + L + + ++ ++ Q I+
Sbjct: 395 -KQLMGTVEE----LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMK 449
Query: 432 ---LKERLSQLETENKELLIEIQTVRGSNEEVTLN 463
+++ ++Q+E E++ S +T+N
Sbjct: 450 QELIRQHMAQMEEIKTRHKGEMENALRSYSNITVN 484
Score = 42.3 bits (95), Expect = 0.004
Identities = 67/307 (21%), Positives = 130/307 (42%), Gaps = 25/307 (8%)
Query: 173 ITKNET-DINELRNSIKYLESVKSEYNTANEKL---FEQLNNAVDKQNC-IQEEVDLLKI 227
I++++T ++ +L N +K SE + E+L ++ N ++K ++E V L +
Sbjct: 2103 ISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELVQALLV 2162
Query: 228 ENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEID 287
E++ RD +E+ + EE+L + +E+ EN +E+
Sbjct: 2163 EDRKHF-GAVEAKPELSLEVQLQAERDAIDRKEKEITNL--EEQLEQFREELENKNEEVQ 2219
Query: 288 MLNEKLICDRREFNETMQE---KNILLSDLSKKVNKTERELEEKQEQLTHLM----EQLN 340
L+ +L ++E +QE +N L D +K+ +E + Q H++ Q+
Sbjct: 2220 QLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQII 2279
Query: 341 DTENNSYKLIENMFNKVSQ---IASDFKI---SNQLSCELDDESENTYERISLTLDKITN 394
+ + K+ Q I +D K+ N+L +L+ + E
Sbjct: 2280 QEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQECVKRNREE 2339
Query: 395 HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVR 454
I LN I + Q+ + A + + L+E+ LK +L + E +L +E Q V
Sbjct: 2340 EIEQLNEVIEKLQQ-ELANIGQKTSMNAHSLSEEADSLKHQLDVVIAE--KLALE-QQVE 2395
Query: 455 GSNEEVT 461
+NEE+T
Sbjct: 2396 TANEEMT 2402
Score = 36.3 bits (80), Expect = 0.26
Identities = 41/161 (25%), Positives = 82/161 (50%), Gaps = 11/161 (6%)
Query: 260 LEEMKTMLVEEKLSEIKEK-DENFKQEIDMLN--EKLICDRREFNETMQEKNILLSDLSK 316
L+E++ L EEK S I E +E K ++D L +++ DR+ +T+Q + ++ K
Sbjct: 3337 LKELQKQL-EEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQK 3395
Query: 317 KVNKTERELEEKQEQLTHLMEQLN--DTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
K+++ + ++E+ Q QL +Q+ D E + I F K + + S ++ +
Sbjct: 3396 KMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQN 3455
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL 415
+E T+ SLT D+ N + + ET++++ A+L+
Sbjct: 3456 LNE-PTTW---SLTSDRTRNWVLQQKIE-GETKESNYAKLI 3491
Score = 35.9 bits (79), Expect = 0.34
Identities = 81/368 (22%), Positives = 152/368 (41%), Gaps = 38/368 (10%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN-GFE-SLEEVALEIDLKKNSITKD 161
ELE + N DV SL + + T+T+ G E S+ +V + + +D
Sbjct: 996 ELEIIINHN---RAEDVQSCDTQESSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVED 1052
Query: 162 NISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEE 221
+S + + +K E I + S+ S+++ + N+KL ++LN +QN ++
Sbjct: 1053 KVSFENMTVGEESKQEQLILDHLPSVTKESSLRATQPSENDKLQKELNVLKSEQNDLR-- 1110
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN 281
L++E Q + +DK + +L+E EEK+ E+
Sbjct: 1111 ---LQMEAQRICLSLVYSTHVDQVREYMENEKDKALCSLKEELIFAQEEKIKEL------ 1161
Query: 282 FKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLND 341
Q+I L E +E + + ++L+ L K V+ EE L L L +
Sbjct: 1162 --QKIHQL-ELQTMKTQETGDEGKPLHLLIGKLQKAVS------EECSYFLQTLCSVLGE 1212
Query: 342 TENNSYKLIENMFNKVSQIASDFKISNQLSCELDD---ESENTYERISLTLDKIT---NH 395
+ K N +K + + D+ IS EL D E ++ E + L+K+T N
Sbjct: 1213 YYTPALKCEVNAEDK--ENSGDY-ISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNK 1269
Query: 396 ITYLNTQINET--QKNDNAQLLWEAKKQIADLTEQNIILKE--RLSQLETENKELLIEIQ 451
+ L T++++ Q+ D +L + + + TE I + L ++ +K L +Q
Sbjct: 1270 LLVLQTRLSKIWGQQTDGMKLEFGEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQ 1329
Query: 452 TVRGSNEE 459
+ + E
Sbjct: 1330 DLEKTKLE 1337
Score = 33.5 bits (73), Expect = 1.8
Identities = 16/82 (19%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
EE + + + +++ +++ D N K ++ L + ++ + E +QE L+S L +++ +
Sbjct: 1300 EETEFLSIHSQMTNLEDIDVNHKSKLSSLQD---LEKTKLEEQVQELESLISSLQQQLKE 1356
Query: 321 TERELEEKQEQLTHLMEQLNDT 342
TE+ E + L ++ ++++
Sbjct: 1357 TEQNYEAEIHCLQKRLQAVSES 1378
Score = 32.7 bits (71), Expect = 3.2
Identities = 72/409 (17%), Positives = 176/409 (43%), Gaps = 29/409 (7%)
Query: 123 VPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINE 182
V +++++++E + L + + E+ E +K T+ + L ++L ++ +
Sbjct: 1854 VEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAR-EQ 1912
Query: 183 LRNSIKYLESVKSEY---NTANEKLFEQLNNAVDKQN----CIQEEVDLLKIENQNLLQX 235
L + E V Y T E+ ++ + +D+ C + L+ E Q + +
Sbjct: 1913 LAVELSKAEGVIDGYADEKTLFERQIQEKTDVIDRLEQELLCASNRLQELEAEQQQIQEE 1972
Query: 236 XXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC 295
++ + L+E + L++EKL E++ + E + ++ + L
Sbjct: 1973 RELLSRQKEAMKAEAGPVEQQL--LQETEK-LMKEKL-EVQCQAEKVRDDLQKQVKALEI 2028
Query: 296 DRRE----FNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIE 351
D E F E QEKN L DL ++ E++LE+ ++ L EQ D E+ +
Sbjct: 2029 DVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRK---FLDEQAIDREHER----D 2081
Query: 352 NMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-- 409
++ ++ K+ + + + E+++ L + T+ + L + Q++
Sbjct: 2082 VFQQEIQKLEQQLKVVPRFQ-PISEHQTREVEQLANHLKEKTDKCSELLLSKEQLQRDIQ 2140
Query: 410 DNAQLLWEAKKQIADLTEQNIILKERLSQLETENK-ELLIEIQTVRGSNEEVTLNLKDSS 468
+ + + + + ++ +L Q +++++R E K EL +E+Q ++ + + K+ +
Sbjct: 2141 ERNEEIEKLEFRVRELV-QALLVEDRKHFGAVEAKPELSLEVQ-LQAERDAIDRKEKEIT 2198
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
N+ E+++ M+ + Q ++ +++ ++E KL K
Sbjct: 2199 NLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFK 2247
Score = 32.7 bits (71), Expect = 3.2
Identities = 36/173 (20%), Positives = 80/173 (46%), Gaps = 12/173 (6%)
Query: 299 EFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
E E + + +++++L ++ +T+ ELE + +++L + +
Sbjct: 3141 ELQEQLSSEKMVVAELKSELAQTKLELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLND 3200
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQL--LW 416
+AS+ K S +L L+ E ++ + ++ + L + E+QK N QL L
Sbjct: 3201 TLASEHKKSRELQWALEKEKA----KLGRSEERDKEELEDLKFSL-ESQKQRNLQLNLLL 3255
Query: 417 EAKKQIADLTEQNI-----ILKERLSQLETENKELLIEIQTVRGSNEEVTLNL 464
E +KQ+ + ++Q I + +LS+ + N EL + +Q+ + E++ L
Sbjct: 3256 EQQKQLLNESQQKIESQRMLYDAQLSEEQGRNLELQVLLQSQKVRIREMSSTL 3308
>M21664-1|AAA36344.1| 532|Homo sapiens protein ( Human alpha-myosin
heavy chain mRNA, 3' end. ).
Length = 532
Score = 52.0 bits (119), Expect = 5e-06
Identities = 69/344 (20%), Positives = 143/344 (41%), Gaps = 16/344 (4%)
Query: 103 SELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL----EEVALEIDLKKNSI 158
S LE K +Q D+MV E ++ ++ F+ + ++ E + S
Sbjct: 8 SSLEKTKHR-LQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESS 66
Query: 159 TKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCI 218
K+ S+ T L KL E + L + ++++ E + E+L E N + + +
Sbjct: 67 QKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEK-V 125
Query: 219 QEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXAR-DKFIANLEEMKTMLVEEKLSEIKE 277
+ ++++ K+E Q+ L+ ++ A +E V EK E+++
Sbjct: 126 RNQLEVEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERN----VAEKDEEMEQ 181
Query: 278 KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK---KVNKTERELEEKQEQLTH 334
N ++ +D L L + R NE ++ K + DL++ +++ R E Q+Q+
Sbjct: 182 AKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 241
Query: 335 LMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITN 394
L L DT+ + + IA + +N L EL +E E+ +
Sbjct: 242 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL-EELRAVVEQTERSRKLAEQ 300
Query: 395 HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
+ + ++ + + N L+ + KK ADL++ ++E + +
Sbjct: 301 ELIETSERV-QLLHSQNTSLINQKKKMDADLSQLQSEVEEAVQE 343
Score = 43.2 bits (97), Expect = 0.002
Identities = 70/401 (17%), Positives = 161/401 (40%), Gaps = 35/401 (8%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVMVV----PEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + + L +V N L E +
Sbjct: 80 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRNQLEVEKMELQSA 139
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLDKLITKNETDINEL-RNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK +++ + + + ++ + RN + ++S+++ +
Sbjct: 140 LEEAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEEMEQAKRNHQRVVDSLQTSLDA 199
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E L + + E L N+ + D +
Sbjct: 200 ETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 259
Query: 260 LEEMK--TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K +VE + + ++ + E + ++ +E ET + +L S +
Sbjct: 260 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 319
Query: 318 VN---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS------- 367
+N K + +L + Q ++ +++ + E + K I + ++ + S
Sbjct: 320 INQKKKMDADLSQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMK 379
Query: 368 -------NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN--DNAQLLWEA 418
L LD+ + + L K+ + L ++ QK ++ + + ++
Sbjct: 380 KNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGMRKS 439
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
+++I +LT Q K+ L +L+ +L ++++ +G EE
Sbjct: 440 ERRIKELTYQTEEDKKNLLRLQDLVNKLQLKVKAYKGQAEE 480
>D64159-1|BAA21515.1| 709|Homo sapiens 3-7 gene product protein.
Length = 709
Score = 52.0 bits (119), Expect = 5e-06
Identities = 89/451 (19%), Positives = 191/451 (42%), Gaps = 30/451 (6%)
Query: 24 IRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEK 83
+R+++ E+ + K L ++ V ELK D N ++ + ++K
Sbjct: 245 VRVDKLESEVSRYKERLH-DIEFYKARVEELKED--NQVLLETKTMLEDQLEGTRARSDK 301
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
L E ++ LK D E + +++ ++ ++ + S+ E ++ G+E
Sbjct: 302 LHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHL---GWE- 357
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
LE+++ +L + + L + K E + L +++ L + K
Sbjct: 358 LEQISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASK 417
Query: 204 LFEQLNNAVDKQNC-IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ + ++K+N + ++V++L+ E Q +K I L E
Sbjct: 418 ILK-----MEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRE 472
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKL-ICDRREFNETMQEKNIL---LSDLSKKV 318
E ++ +++++E+ Q + L ++ I + +E IL + + S K+
Sbjct: 473 NS----ERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKL 528
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN-QLSCELDD- 376
+K E E + +++L H E+ E +L + K +++ KI+N +++CE +
Sbjct: 529 SKIEFEKRQIKKELEHYKEKGERAEELENEL--HHLEKENELLQK-KITNLKITCEKIEA 585
Query: 377 -ESENT-YERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
E EN+ ER + L K + L Q+ +K +N+QL E ++ E
Sbjct: 586 LEQENSELERENRKLKKTLDSFKNLTFQLESLEK-ENSQLD-EENLELRRNVESLKCASM 643
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
+++QL+ ENKEL E + ++ E + + K
Sbjct: 644 KMAQLQLENKELESEKEQLKKGLELLKASFK 674
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
E+ Q ++ L+D K+ + +ELEEK EQL ++L E +L + N +S
Sbjct: 169 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 228
Query: 362 SDFKISNQLSC--ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
S ++L E + +S +++ + I + ++ E K DN Q+L E K
Sbjct: 229 SARMYRDELDALREKAVRVDKLESEVSRYKERL-HDIEFYKARVEEL-KEDN-QVLLETK 285
Query: 420 KQIADLTEQNIILKERLSQLETENKEL 446
+ D E ++L +LE EN +L
Sbjct: 286 TMLEDQLEGTRARSDKLHELEKENLQL 312
Score = 35.1 bits (77), Expect = 0.60
Identities = 83/452 (18%), Positives = 176/452 (38%), Gaps = 30/452 (6%)
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
+ + + D++ L ++ A L+ L E + H+ ++ + E D L + + ++
Sbjct: 101 MEVTDMSQEDIEPLLKNMALHLKRLIDERDE-HSETIIELSEERDGLHFLPHASSSAQSP 159
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
++ + ++ + K + +L + E +L + + LE ++ E ++
Sbjct: 160 CGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE 219
Query: 204 LFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN-- 259
L++A + ++E+D L K + L+ AR + +
Sbjct: 220 NMNLLSDARSAR-MYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDN 278
Query: 260 --LEEMKTMLVEE---------KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
L E KTML ++ KL E+++++ K ++ + + DR++ E M+E N
Sbjct: 279 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE-N 337
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN 368
+ L K+ L + EQ++ E L++ S L + S ++ N
Sbjct: 338 MTLEMAQKQSMDESLHLGWELEQISRTSE-LSEAPQKS--LGHEVNELTSSRLLKLEMEN 394
Query: 369 QLSCELDDESENTYERISLTLDKI-----TNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
Q + +E T + + KI N +I E + Q L +
Sbjct: 395 QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 454
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL-NLKDSSTXXXXXXXXXXXXS 482
DL ++ L++ + L EN E I+I + T+ +L+ S
Sbjct: 455 DLMKEKAQLEKTIETLR-ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE 513
Query: 483 NEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
N+I + + E S+ ++ +Q +KEL+
Sbjct: 514 NKI--LHESIKETSSKLSKIEFEKRQIKKELE 543
>BX537985-1|CAD97945.1| 1202|Homo sapiens hypothetical protein
protein.
Length = 1202
Score = 52.0 bits (119), Expect = 5e-06
Identities = 108/502 (21%), Positives = 204/502 (40%), Gaps = 38/502 (7%)
Query: 24 IRLEECYKEIGQLKS----GLQQNVGVGDKTVAE-LKNDEINSMIRQLXXXXXXXXXXXX 78
+RL+E KE +L ++ V + + V+E LK ++N+ + +L
Sbjct: 56 VRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKIGLNKE 115
Query: 79 XLT-EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTL 137
L ++ + ++++ L+ E + + +K E I + + L + + T+
Sbjct: 116 RLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQELKTV 175
Query: 138 TNGFESLEEVALEIDLKKNSIT---KDNI----SIKTLLDKLITKNETDINELRNSIKYL 190
+E+L++ E + ++S +DN S +T + L K+ + E+ + L
Sbjct: 176 KKNYEALKQRQDEERMVQSSPPISGEDNKWERESQETTRELLKVKDR--LIEVERNNATL 233
Query: 191 ESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXX 250
++ K T ++L Q NN + +Q + L+ +N L
Sbjct: 234 QAEKQALKTQLKQLETQNNNLQTQILALQRQTVSLQEQNTTLQTQNAKLQVENSTLNSQS 293
Query: 251 XARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDML---NEKL-ICDRREFNE--TM 304
+ A L ++ L E S IKE+ E+ K D L +EKL + R+ +E ++
Sbjct: 294 TSLMNQNAQLLIQQSSLENENESVIKER-EDLKSLYDSLIKDHEKLELLHERQASEYESL 352
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF--NKVSQ-IA 361
K+ L K + R+LE++ QL QL D E E M NK + +A
Sbjct: 353 ISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLLENKNHETVA 412
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKI-TNHITYL----NTQINETQKNDNAQLLW 416
+++K C +D +TY ++ + + T+H N+++ +T+ L
Sbjct: 413 AEYK----KLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTRLEAEFSKLK 468
Query: 417 EAKKQI----ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
E +Q+ L Q +L + LE EN+ LL +IQT+ N + +S
Sbjct: 469 EQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQNMESKDLFH 528
Query: 473 XXXXXXXXXSNEIEDMKTKVME 494
NE+ K K+ E
Sbjct: 529 VEQRQYIDKLNELRRQKEKLEE 550
Score = 50.4 bits (115), Expect = 1e-05
Identities = 75/360 (20%), Positives = 153/360 (42%), Gaps = 27/360 (7%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKL-FEQLNNAVDKQNCIQEEVDLLKI 227
L +L +N+ + IK L +++ + +EKL +Q+NN ++K + E++ + +
Sbjct: 58 LKELEKENKELVKRATIDIKTLVTLREDL--VSEKLKTQQMNNDLEK---LTHELEKIGL 112
Query: 228 ENQNLLQXXXXXXXXXXXXXXXXXARD-KFIANLEEMKTMLVEEKLSEIKEKDENFKQEI 286
+ LL K ++E K +E +L E ++ +QE+
Sbjct: 113 NKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQEL 172
Query: 287 DMLNEKL-ICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN 345
+ + +R+ E M + + +S + NK ERE +E +L + ++L + E N
Sbjct: 173 KTVKKNYEALKQRQDEERMVQSS---PPISGEDNKWERESQETTRELLKVKDRLIEVERN 229
Query: 346 SYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY--ERISLTLDKITNHITYLNTQI 403
+ L +Q+ +N L ++ T + + TL + N+ +
Sbjct: 230 NATLQAEKQALKTQLKQLETQNNNLQTQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 289
Query: 404 NETQK---NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL-----IEIQTVRG 455
N N NAQLL + Q + E ++KER L++ L+ +E+ R
Sbjct: 290 NSQSTSLMNQNAQLLIQ---QSSLENENESVIKER-EDLKSLYDSLIKDHEKLELLHERQ 345
Query: 456 SNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
++E +L K + ++ED ++++ K Q EDL+ ++K +Q+++ L
Sbjct: 346 ASEYESLISKHGTLKSAHKNLEVEH--RDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLL 403
Score = 41.1 bits (92), Expect = 0.009
Identities = 67/316 (21%), Positives = 138/316 (43%), Gaps = 34/316 (10%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEE--VDLLK 226
L+K + E + LR + ++ E N L E+ N + K+ I +E V L +
Sbjct: 2 LEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNL-EKENKTLSKEIGIYKESCVRLKE 60
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEI 286
+E +N R+ ++ E++KT + L ++ + E +I
Sbjct: 61 LEKEN----KELVKRATIDIKTLVTLREDLVS--EKLKTQQMNNDLEKLTHELE----KI 110
Query: 287 DMLNEKLICDRREFNETMQE--KNILLSDLSKKVNKTERE---LEEKQEQLTHLMEQLND 341
+ E+L+ D + +++ + ++ L S L K + E + LE + E+ T+ +QL
Sbjct: 111 GLNKERLLHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLRQ 170
Query: 342 ---TENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKIT----N 394
T +Y+ ++ ++ + S IS + + + + ES+ T + D++ N
Sbjct: 171 ELKTVKKNYEALKQRQDEERMVQSSPPISGEDN-KWERESQETTRELLKVKDRLIEVERN 229
Query: 395 HITY------LNTQIN--ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
+ T L TQ+ ETQ N+ + ++Q L EQN L+ + ++L+ EN L
Sbjct: 230 NATLQAEKQALKTQLKQLETQNNNLQTQILALQRQTVSLQEQNTTLQTQNAKLQVENSTL 289
Query: 447 LIEIQTVRGSNEEVTL 462
+ ++ N ++ +
Sbjct: 290 NSQSTSLMNQNAQLLI 305
>BC029420-1|AAH29420.1| 427|Homo sapiens Unknown (protein for
IMAGE:4737945) protein.
Length = 427
Score = 52.0 bits (119), Expect = 5e-06
Identities = 71/353 (20%), Positives = 147/353 (41%), Gaps = 31/353 (8%)
Query: 111 ENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLD 170
E I +++ + I E++ + F+S++ +ALE L+K + ++ ++L
Sbjct: 76 EKINFENANLSALNLKISEQKEILIKELDTFKSVK-LALEHLLRKRDYKQTGDNLSSMLL 134
Query: 171 KLITKNETDINELRNSIKYLESVKSEY---------NTANEKLFEQLNNAVDKQNCIQEE 221
+ +T NE++ L+ + E+ E NT F Q V ++ +Q +
Sbjct: 135 ENLTDNESENTNLKKKVFEKEAHIQELSCLFQSEKANTLKANRFSQSVKVVHER--LQIQ 192
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE---MKTMLVEEKLSEIKEK 278
+ + EN + ++E KT+ +++ K++
Sbjct: 193 IHKREAENDKSKEYVKSLETKIAKWNLQSRMNKNEAIVMKEASRQKTVALKKASKVYKQR 252
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK-KVNKTERE--LEEKQEQLTHL 335
++F I+ L ++ + +ET+ N S K + KTE E +E ++Q+ +L
Sbjct: 253 LDHFTGAIEKLTSQIRDQEAKLSETISASNAWKSHYEKIVIEKTELEVQIETMKKQIINL 312
Query: 336 MEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNH 395
+E L E++ E + KV I + + N ENT ++ TL + +
Sbjct: 313 LEDLKKMEDHGKNSCEEILRKVHSIEYENETLN---------LENT--KLKTTLAALKDE 361
Query: 396 ITYLNTQINETQKNDNAQ--LLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
+ + +++E Q+ + Q L+ K Q+ L E I+K R L +N ++
Sbjct: 362 VVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLLHKNNQI 414
>AY681966-1|AAV87216.1| 2069|Homo sapiens citron protein.
Length = 2069
Score = 52.0 bits (119), Expect = 5e-06
Identities = 81/445 (18%), Positives = 183/445 (41%), Gaps = 25/445 (5%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L +K E K L + ++ E L+ +Q H + +I+ +IN + +
Sbjct: 756 LKQKEQHYEEKIKVLDNQIKKDLADKETLENM-MQRHEEEAHEKGKILSEQKAMINAMDS 814
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNT 199
SLE+ +E+ + N + N S+ T + + E I+ELR YLE+ +
Sbjct: 815 KIRSLEQRIVELS-EANKLAA-NSSLFT--QRNMKAQEEMISELRQQKFYLETQAGKLEA 870
Query: 200 ANEKLFEQL-----NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
N KL EQL + DK ++ E L ++ ++ Q R+
Sbjct: 871 QNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQ-KLELKRQLTELQLSLQERE 929
Query: 255 KFIANLEEMKTML---VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+ L+ + L + + +E++E ++EI L +R+F + ++ ++
Sbjct: 930 SQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKF-DALRNSCTVI 988
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
+DL +++N+ + E Q +L +QL++ + ++++ + ++V + + +
Sbjct: 989 TDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQ-LRSEVDHLRREI---TERE 1044
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA--DLTEQN 429
+L + + T E + T + + L +E + + WEA + + + ++
Sbjct: 1045 MQLTSQKQ-TMEALKTTCTMLEEQVMDLEALNDELLEKERQ---WEAWRSVLGDEKSQFE 1100
Query: 430 IILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
++E L+TE + Q + S + V L +K+ + E +
Sbjct: 1101 CRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLS 1160
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELK 514
K+ + + + L+ + Q++L+
Sbjct: 1161 DKLNDLEKKHAMLEMNARSLQQKLE 1185
Score = 37.1 bits (82), Expect = 0.15
Identities = 56/278 (20%), Positives = 114/278 (41%), Gaps = 21/278 (7%)
Query: 83 KLTIAETKHNDLKKLYEDSASELE---ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
+LT + L+ + +ELE A E IQ T+ + D+L +T+
Sbjct: 931 QLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITD 990
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL--ESVKSEY 197
LEE ++ + N + LD+ N+ +I +LR+ + +L E + E
Sbjct: 991 ----LEEQLNQLTEDNAELNNQNFYLSKQLDEASGAND-EIVQLRSEVDHLRREITEREM 1045
Query: 198 NTANEKLFEQLNNAVDKQNC--IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
++K Q A+ K C ++E+V L+ N LL+ + +
Sbjct: 1046 QLTSQK---QTMEAL-KTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDE---KSQ 1098
Query: 256 FIANLEEMKTMLVEEKLSEIK--EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
F + E++ ML EK S + ++ +Q +++ ++ + + ++E+ +
Sbjct: 1099 FECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAES 1158
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIE 351
LS K+N E++ + L ++L +L+E
Sbjct: 1159 LSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLE 1196
>AY257469-1|AAP13528.1| 2027|Homo sapiens rho/rac-interacting citron
kinase protein.
Length = 2027
Score = 52.0 bits (119), Expect = 5e-06
Identities = 81/445 (18%), Positives = 183/445 (41%), Gaps = 25/445 (5%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L +K E K L + ++ E L+ +Q H + +I+ +IN + +
Sbjct: 714 LKQKEQHYEEKIKVLDNQIKKDLADKETLENM-MQRHEEEAHEKGKILSEQKAMINAMDS 772
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNT 199
SLE+ +E+ + N + N S+ T + + E I+ELR YLE+ +
Sbjct: 773 KIRSLEQRIVELS-EANKLAA-NSSLFT--QRNMKAQEEMISELRQQKFYLETQAGKLEA 828
Query: 200 ANEKLFEQL-----NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
N KL EQL + DK ++ E L ++ ++ Q R+
Sbjct: 829 QNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQ-KLELKRQLTELQLSLQERE 887
Query: 255 KFIANLEEMKTML---VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+ L+ + L + + +E++E ++EI L +R+F + ++ ++
Sbjct: 888 SQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKF-DALRNSCTVI 946
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
+DL +++N+ + E Q +L +QL++ + ++++ + ++V + + +
Sbjct: 947 TDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQ-LRSEVDHLRREI---TERE 1002
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA--DLTEQN 429
+L + + T E + T + + L +E + + WEA + + + ++
Sbjct: 1003 MQLTSQKQ-TMEALKTTCTMLEEQVMDLEALNDELLEKERQ---WEAWRSVLGDEKSQFE 1058
Query: 430 IILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
++E L+TE + Q + S + V L +K+ + E +
Sbjct: 1059 CRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLS 1118
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELK 514
K+ + + + L+ + Q++L+
Sbjct: 1119 DKLNDLEKKHAMLEMNARSLQQKLE 1143
Score = 37.1 bits (82), Expect = 0.15
Identities = 56/278 (20%), Positives = 114/278 (41%), Gaps = 21/278 (7%)
Query: 83 KLTIAETKHNDLKKLYEDSASELE---ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
+LT + L+ + +ELE A E IQ T+ + D+L +T+
Sbjct: 889 QLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITD 948
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL--ESVKSEY 197
LEE ++ + N + LD+ N+ +I +LR+ + +L E + E
Sbjct: 949 ----LEEQLNQLTEDNAELNNQNFYLSKQLDEASGAND-EIVQLRSEVDHLRREITEREM 1003
Query: 198 NTANEKLFEQLNNAVDKQNC--IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
++K Q A+ K C ++E+V L+ N LL+ + +
Sbjct: 1004 QLTSQK---QTMEAL-KTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDE---KSQ 1056
Query: 256 FIANLEEMKTMLVEEKLSEIK--EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
F + E++ ML EK S + ++ +Q +++ ++ + + ++E+ +
Sbjct: 1057 FECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAES 1116
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIE 351
LS K+N E++ + L ++L +L+E
Sbjct: 1117 LSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLE 1154
>AB023166-1|BAA76793.2| 1559|Homo sapiens KIAA0949 protein protein.
Length = 1559
Score = 52.0 bits (119), Expect = 5e-06
Identities = 81/445 (18%), Positives = 183/445 (41%), Gaps = 25/445 (5%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L +K E K L + ++ E L+ +Q H + +I+ +IN + +
Sbjct: 262 LKQKEQHYEEKIKVLDNQIKKDLADKETLENM-MQRHEEEAHEKGKILSEQKAMINAMDS 320
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNT 199
SLE+ +E+ + N + N S+ T + + E I+ELR YLE+ +
Sbjct: 321 KIRSLEQRIVELS-EANKLAA-NSSLFT--QRNMKAQEEMISELRQQKFYLETQAGKLEA 376
Query: 200 ANEKLFEQL-----NNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
N KL EQL + DK ++ E L ++ ++ Q R+
Sbjct: 377 QNRKLEEQLEKISHQDHSDKNRLLELETRLREVSLEHEEQ-KLELKRQLTELQLSLQERE 435
Query: 255 KFIANLEEMKTML---VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+ L+ + L + + +E++E ++EI L +R+F + ++ ++
Sbjct: 436 SQLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKF-DALRNSCTVI 494
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
+DL +++N+ + E Q +L +QL++ + ++++ + ++V + + +
Sbjct: 495 TDLEEQLNQLTEDNAELNNQNFYLSKQLDEASGANDEIVQ-LRSEVDHLRREI---TERE 550
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA--DLTEQN 429
+L + + T E + T + + L +E + + WEA + + + ++
Sbjct: 551 MQLTSQKQ-TMEALKTTCTMLEEQVMDLEALNDELLEKERQ---WEAWRSVLGDEKSQFE 606
Query: 430 IILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
++E L+TE + Q + S + V L +K+ + E +
Sbjct: 607 CRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAESLS 666
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELK 514
K+ + + + L+ + Q++L+
Sbjct: 667 DKLNDLEKKHAMLEMNARSLQQKLE 691
Score = 37.1 bits (82), Expect = 0.15
Identities = 56/278 (20%), Positives = 114/278 (41%), Gaps = 21/278 (7%)
Query: 83 KLTIAETKHNDLKKLYEDSASELE---ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
+LT + L+ + +ELE A E IQ T+ + D+L +T+
Sbjct: 437 QLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITD 496
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL--ESVKSEY 197
LEE ++ + N + LD+ N+ +I +LR+ + +L E + E
Sbjct: 497 ----LEEQLNQLTEDNAELNNQNFYLSKQLDEASGAND-EIVQLRSEVDHLRREITEREM 551
Query: 198 NTANEKLFEQLNNAVDKQNC--IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
++K Q A+ K C ++E+V L+ N LL+ + +
Sbjct: 552 QLTSQK---QTMEAL-KTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDE---KSQ 604
Query: 256 FIANLEEMKTMLVEEKLSEIK--EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
F + E++ ML EK S + ++ +Q +++ ++ + + ++E+ +
Sbjct: 605 FECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAES 664
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIE 351
LS K+N E++ + L ++L +L+E
Sbjct: 665 LSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLE 702
>X51591-1|CAA35940.1| 1151|Homo sapiens beta-myosin heavy chain
(1151 AA) protein.
Length = 1151
Score = 51.6 bits (118), Expect = 6e-06
Identities = 96/492 (19%), Positives = 197/492 (40%), Gaps = 44/492 (8%)
Query: 41 QQNVGVGDKTVAEL-KND-EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLY 98
Q N+ ++ +L KN ++ + ++++ LT K E + ++LK+
Sbjct: 111 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 170
Query: 99 EDSASELEALKREN------IQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+D L +++E ++ T ++ + EII LT+ L + +L+++ E
Sbjct: 171 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 230
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
D K N++TK + K E +++L S++ + V+ + A KL L
Sbjct: 231 D-KVNTLTKAKV-----------KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-- 276
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +++ + E D ++E + L + + L+E++ + E+
Sbjct: 277 LTQESIMDLENDKQQLE-ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARI--EE 333
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS---DLSKK----VNKTERE 324
L E E + + +++ L L + E +E ++E S +++KK K R+
Sbjct: 334 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 393
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYE 383
LEE Q L +S + + + ++ K ++ ELDD + N E
Sbjct: 394 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-ME 452
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL--ET 441
+I + L Q+NE + E ++ + DLT Q L+ +L +
Sbjct: 453 QIIKAKANLEKMCRTLEDQMNEHRSKAE-----ETQRSVNDLTSQRAKLQTENGELSRQL 507
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ KE LI Q RG T L+D ++ ++ + + Q+E+
Sbjct: 508 DEKEALIS-QLTRG-KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 565
Query: 502 LDDVMKQQQKEL 513
+ + Q+ L
Sbjct: 566 ETEAKAELQRVL 577
Score = 40.7 bits (91), Expect = 0.012
Identities = 50/260 (19%), Positives = 108/260 (41%), Gaps = 30/260 (11%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDL 314
ANLE+M L E++++E + K E ++ ++ L KL + E + + EK L+S L
Sbjct: 459 ANLEKMCRTL-EDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL 517
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++ ++LE+ + QL E+ +N +++ + + ++ + EL
Sbjct: 518 TRGKLTYTQQLEDLKRQL----EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 573
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+R+ L K + + T+ ET + L EAKK++A +
Sbjct: 574 --------QRV---LSKANSEVAQWRTKY-ETDAIQRTEELEEAKKKLA----------Q 611
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
RL + E + + + ++ + + ++D + + + E
Sbjct: 612 RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 671
Query: 495 WKSQFEDLDDVMKQQQKELK 514
WK ++E+ ++ QKE +
Sbjct: 672 WKQKYEESQSELESSQKEAR 691
Score = 39.5 bits (88), Expect = 0.028
Identities = 73/381 (19%), Positives = 155/381 (40%), Gaps = 29/381 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 700 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 759
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLD-KLITKNETDINELRNSIKYLESVK----S 195
LEE ++ ++ I + + IK ++ KL K+E RN ++ ++S++ +
Sbjct: 760 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 819
Query: 196 EYNTANE--KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQX-XXXXXXXXXXXXXXXXA 252
E + NE ++ +++ +++ + + E Q ++ A
Sbjct: 820 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 879
Query: 253 RDKFIANLE--EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL 310
D N+ E + L++ +L E++ E ++ + +E+LI + E + + +N
Sbjct: 880 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLADEELI-ETSERVQLLHSQNTS 938
Query: 311 LSDLSKK----VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI 366
L + KK +++ + E+EE ++ + E+ ++ + E + + A ++
Sbjct: 939 LINQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERM 998
Query: 367 SNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLT 426
+ + D E + L + L ++ E + A+ A + + +
Sbjct: 999 KKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNA-ESVKGMR 1057
Query: 427 EQNIILKERLSQLETENKELL 447
+ +KE Q E + K LL
Sbjct: 1058 KSERRIKELTYQTEEDRKNLL 1078
Score = 36.3 bits (80), Expect = 0.26
Identities = 100/489 (20%), Positives = 191/489 (39%), Gaps = 46/489 (9%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q ++ V + + L+ + + + I L L +K
Sbjct: 602 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 661
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF-E 142
+ + K+ YE+S SELE+ ++E SL+ + L N + E
Sbjct: 662 QRNFDKILAEWKQKYEESQSELESSQKE---------------ARSLSTELFKLKNAYEE 706
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
SLE LE ++N ++ IS L ++L + +T I+EL K LE+ K E +A E
Sbjct: 707 SLEH--LETFKRENKNLQEEIS--DLTEQLGSSGKT-IHELEKVRKQLEAEKMELQSALE 761
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ L + K Q E + +K E + L A+ + ++
Sbjct: 762 EAEASLEHEEGKILRAQLEFNQIKAEIERKL---------AEKDEEMEQAKRNHLRVVDS 812
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
++T L E S + K E D LNE I N E + L + T+
Sbjct: 813 LQTSLDAETRSRNEALRVKKKMEGD-LNEMEI-QLSHANRMAAEAQKQVKSLQSLLKDTQ 870
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
+L++ L E + E + L++ ++ + + S +L+ D+E T
Sbjct: 871 IQLDDAVRANDDLKENIAIVERRN-NLLQAELEELRAVVEQTERSRKLA---DEELIETS 926
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
ER+ L + T+ I + D +QL E ++ + + K+ ++
Sbjct: 927 ERVQLLHSQNTSLINQ-----KKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMM 981
Query: 443 NKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDL 502
+EL E Q E + N++ T ++ K ++ + +++ +L
Sbjct: 982 AEELKKE-QDTSAHLERMKKNME--QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVREL 1038
Query: 503 DDVMKQQQK 511
++ ++ +QK
Sbjct: 1039 ENELEAEQK 1047
Score = 35.5 bits (78), Expect = 0.46
Identities = 38/222 (17%), Positives = 98/222 (44%), Gaps = 6/222 (2%)
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+R + +M+E+ L + +K +ELEEK + L+++ ND + +N+ +
Sbjct: 60 EREKEMASMKEEFTRLKEALEKSEARRKELEEK---MVSLLQEKNDLQLQVQAEQDNLAD 116
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQL 414
+ K QL ++ + +E + + + +T L + +E +++ D+ +L
Sbjct: 117 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKRDIDDLEL 175
Query: 415 LWEAKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 176 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 235
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 236 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 277
>X03741-1|CAA27381.1| 635|Homo sapiens protein ( Human cardiac mRNA
for myosin heavy chain light meromyosin region. ).
Length = 635
Score = 51.6 bits (118), Expect = 6e-06
Identities = 80/421 (19%), Positives = 169/421 (40%), Gaps = 24/421 (5%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLT 85
L E Y+E + K+ LQ ++ + VA+ + I++ L ++L
Sbjct: 43 LREQYEEETEAKARLQGDLSKANSEVAQWRTKYETDAIQR----TEELEEAKKKLAQRLQ 98
Query: 86 IAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL- 144
AE + + S LE K +Q D+MV E ++ ++ F+ +
Sbjct: 99 EAE----EAVEAVNAKCSSLEKTKHR-LQNEIEDLMVDVERSNAAAAALDKKQRNFDKIL 153
Query: 145 ---EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++ E + S K+ S+ T L KL E + L + ++++ E +
Sbjct: 154 AEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLT 213
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXAR-DKFIANL 260
E+L + + ++++++ K+E Q+ L+ ++ A +
Sbjct: 214 EQLGSS-GKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 272
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK---K 317
E + +EK E+++ N + +D L L + R NE ++ K + DL++ +
Sbjct: 273 ERKR----QEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQ 328
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE 377
++ R E Q+Q+ L L DT+ + + IA + +N L EL +E
Sbjct: 329 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL-EE 387
Query: 378 SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS 437
E+ + + + ++ + + N L+ + KK ADL++ ++E +
Sbjct: 388 LRAVVEQTERSRKLAEQELIETSERV-QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQ 446
Query: 438 Q 438
+
Sbjct: 447 E 447
Score = 39.5 bits (88), Expect = 0.028
Identities = 39/193 (20%), Positives = 86/193 (44%), Gaps = 6/193 (3%)
Query: 273 SEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQL 332
SE+ + ++ + E+L +++ + +QE + ++ K + E+ Q ++
Sbjct: 66 SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEI 125
Query: 333 THLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKI 392
LM + + N + ++ +I +++K + S + S+ +S L K+
Sbjct: 126 EDLMVDV-ERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKL 184
Query: 393 TNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQT 452
N + ET K +N L +++I+DLTEQ + + +LE K+L E
Sbjct: 185 KNAYEESLEHL-ETFKRENKNL----QEEISDLTEQLGSSGKTIHELEKVRKQLEAEKME 239
Query: 453 VRGSNEEVTLNLK 465
++ + EE +L+
Sbjct: 240 LQSALEEAEASLE 252
>U31906-1|AAC51791.1| 2083|Homo sapiens golgin-245 protein.
Length = 2083
Score = 51.6 bits (118), Expect = 6e-06
Identities = 92/442 (20%), Positives = 191/442 (43%), Gaps = 31/442 (7%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEII--DSLTEVINTLTNGFESLEEVALE- 150
L+KL+E + E + +Q + ++ S +E + ++ E E +ALE
Sbjct: 336 LQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK-ISQEKEQQESLALEE 394
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN 210
++L+K +I ++ + L + T I EL +S LE E ++ L L
Sbjct: 395 LELQKKAILTESENKLRDLQQEAETYRTRILELESS---LEKSLQENENQSKDLAVHLEA 451
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE 270
+K N +E+ ++ +++ L+ + ++ +E+++ +E
Sbjct: 452 EKNKHN---KEITVMVEKHKTELESLKHQQDALWAEELQVL-KQQYQTEMEKLREKCEQE 507
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNET-MQEKNILLSDLSKKVNKTERELEEKQ 329
K + +K+K+ F+ I+ +NEK + ++ + N+T ++ + LS++ K +K E EL +
Sbjct: 508 KETLLKDKEIIFQAHIEEMNEKTL-EKLDVNQTELESLSSELSEVLKARHKLEEELSVLK 566
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+Q T M+Q + + + K + +V I + ++S Q + + + N E +
Sbjct: 567 DQ-TDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKER 623
Query: 390 DKITN----HITYLNTQINETQ--------KNDNAQLLWEA-KKQIADLTEQNIILKERL 436
DK H+ L I ++ K D Q A +Q EQ L+++L
Sbjct: 624 DKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKL 683
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED-MKTKVMEW 495
LETE L ++ V ++V L ++E+E +K+ +
Sbjct: 684 LDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVY 743
Query: 496 KSQFEDLDDVMKQQQKELKLGK 517
+S+ ED + ++Q K++ + K
Sbjct: 744 ESKLED-GNKEQEQTKQILVEK 764
Score = 50.8 bits (116), Expect = 1e-05
Identities = 91/467 (19%), Positives = 199/467 (42%), Gaps = 49/467 (10%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTE-VINTLT 138
LT KL + + LK +E S LE E ++ + ++ + +I TE ++ T
Sbjct: 1029 LTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKL-SEELAIQLDICCKKTEALLEAKT 1087
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYN 198
N ++ L + S + + + + L+ K T ++EL ++ L ++ N
Sbjct: 1088 NELINISSSKTNAILSRISHCQHRTT--KVKEALLIKTCT-VSELEAQLRQLTEEQNTLN 1144
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
+ ++ QL ++ ++ +++ L E + L + K ++
Sbjct: 1145 ISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELS 1204
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
T++ EE L E K + + +++ LN +L + + ++ EK +S L K+
Sbjct: 1205 ENINAVTLMKEE-LKEKKVEISSLSKQLTDLNVQL-----QNSISLSEKEAAISSLRKQY 1258
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQ----IASDF----KISNQL 370
++ + EL ++ + L+ ++ L+ + ++ + +++ NK S+ S F +L
Sbjct: 1259 DEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKEL 1318
Query: 371 SCELDDESENTYER---ISLT---LDKITNHITYLNTQINETQ---KNDNAQLLWEAKKQ 421
+L+ +S+ YE+ I+L LD+ L ++ + + + + L E K Q
Sbjct: 1319 QIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQ 1378
Query: 422 IADLTEQ--------------NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS 467
A + E N +LK Q + E+KEL+ ++Q + EE +K++
Sbjct: 1379 TARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEA 1438
Query: 468 STXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
N++ MK ++ K + E ++ +K +++ELK
Sbjct: 1439 E-------EKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELK 1478
Score = 48.4 bits (110), Expect = 6e-05
Identities = 53/214 (24%), Positives = 100/214 (46%), Gaps = 15/214 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+ K +LVE++ + I + E K+EI++L +KL + +E + KK+ K
Sbjct: 755 EQTKQILVEKE-NMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEK 813
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-----KISNQLSCELD 375
+++ +E QE L ++L D E K +EN ++SQ F +++ S +
Sbjct: 814 VKQKAKEMQET---LKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGIS 870
Query: 376 DESENTYERISLTLDKITN-HITYLNTQIN--ETQKNDNAQLLWEAKK-QIADLTEQNII 431
D ++ +T H LN I+ E + N A+ L E + Q+ + ++
Sbjct: 871 DAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAE 930
Query: 432 LKERLSQLETENKELLIEIQTVR--GSNEEVTLN 463
LK+++ E +E+ EI ++ G ++ TLN
Sbjct: 931 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLN 964
Score = 48.4 bits (110), Expect = 6e-05
Identities = 96/460 (20%), Positives = 178/460 (38%), Gaps = 50/460 (10%)
Query: 100 DSASELEALKRENIQMHTS-DVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
D+ S LE ++E I+ T + ++I + +N + + E+ L+ ++ +
Sbjct: 871 DAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAE 930
Query: 159 TKDNISI----KTLLDKLIT-------KNETDINELRNSIKY-------LESVKSEYNTA 200
K I + K ++K IT K +T +NEL+ +K L +++
Sbjct: 931 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 990
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
EKL LN ++ + +QE++ LK+ L + + + +
Sbjct: 991 LEKLEVDLNKSLKENTFLQEQLVELKM----LAEEDKRKVSELTSKLKTTDEEFQSLKSS 1046
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEK----LICDRREF-NETMQEKNILLSDLS 315
E +E+K E K+ E ++D+ +K L E N + + N +LS +S
Sbjct: 1047 HEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRIS 1106
Query: 316 KKVNKTER-------------ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
++T + ELE + QLT LN + + +E N++ + +
Sbjct: 1107 HCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKA 1166
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
D + L E N + S IT L+ IN L E K +I
Sbjct: 1167 DIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEE--LKEKKVEI 1224
Query: 423 ADLTEQNIILKERL-SQLETENKELLIEIQTVRGSNEEVTL--NLKDSSTXXXXXXXXXX 479
+ L++Q L +L + + KE I + E+ L ++D S
Sbjct: 1225 SSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKI 1284
Query: 480 XXSNEIEDMKTKVMEWK----SQFEDLDDVMKQQQKELKL 515
+++D K EWK S+F + +K+ Q +L+L
Sbjct: 1285 SALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLEL 1324
Score = 45.6 bits (103), Expect = 4e-04
Identities = 75/373 (20%), Positives = 160/373 (42%), Gaps = 32/373 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEI-IDSLTEVINTLT 138
L+E + +LK+ + +S + L N+Q+ S + E I SL + +
Sbjct: 1203 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDE-- 1260
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITK-------NETDINELRNSIKYLE 191
E L++V ++ K ++++K+ IS +D K ++ + +N++K L+
Sbjct: 1261 EKCELLDQVQ-DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQ 1319
Query: 192 ---SVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXX 248
+KS+ ++ L +D+QN + D LK E ++
Sbjct: 1320 IQLELKSKEAYEKDEQINLLKEELDQQN---KRFDCLKGEMEDDKSKMEKKESNLETELK 1376
Query: 249 XXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
AR I LE+ T E + + E +N+ Q+ D+ +++L+ + F E +EK+
Sbjct: 1377 SQTAR---IMELEDHITQKTIE-IESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKD 1432
Query: 309 ILLSDLSKKVNKTER-------ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK-VSQI 360
+ + +K+ E ELE K+++L H+ + E L + + ++ +++
Sbjct: 1433 NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1492
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDKIT-NHITYLNTQINETQKNDNAQLLWEAK 419
A + + Q + + + E K T +H++ LNT++ E ++ +L E
Sbjct: 1493 AELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERER--EVHILEEKL 1550
Query: 420 KQIADLTEQNIIL 432
K + + +I+
Sbjct: 1551 KSVESSQSETLIV 1563
Score = 44.4 bits (100), Expect = 0.001
Identities = 63/353 (17%), Positives = 137/353 (38%), Gaps = 17/353 (4%)
Query: 175 KNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEEVDLLKIENQNLL 233
+ E + + S+ + V+ E N + + L N D Q +QE+ +I Q +
Sbjct: 1653 QEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIK 1712
Query: 234 QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL 293
+ L+ ++ M K +E+ E++ K + ++ KL
Sbjct: 1713 ELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKL 1772
Query: 294 ICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM-EQLNDTENNSYKLIEN 352
+ + + ++ K L+ ++ K +E+ Q+ L L E + E + +
Sbjct: 1773 LSNMEAQHNDLEFK---LAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQE 1829
Query: 353 MFNKVSQIASDFKISN-----QLSCELDDESENTYERISLTLDKITNHITYLNTQINETQ 407
K+ Q D ++ + QL E + + + + +T+ + N + ++ E+
Sbjct: 1830 REEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESH 1889
Query: 408 KNDNAQLLWEAKKQIADL----TEQNIILKERLSQLETENKEL---LIEIQTVRGSNEEV 460
+ + QLL + ++ DL IL R ++ + ++L L E+Q E
Sbjct: 1890 QEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ 1949
Query: 461 TLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
N + + + I D K K E++ Q +L+D +K+ +K +
Sbjct: 1950 EENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNV 2002
Score = 41.9 bits (94), Expect = 0.005
Identities = 95/453 (20%), Positives = 180/453 (39%), Gaps = 46/453 (10%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRE-NIQMHTSDVMVVPEIIDSLTEVINTLT 138
L +KL E K LKK E++A EL +++ N +M I D+++ +
Sbjct: 825 LKKKLLDQEAK---LKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK 881
Query: 139 NGFESLEEVALE-----IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESV 193
ESL EV I + + + + ++ + + + + E ++ EL+ I
Sbjct: 882 EQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCE 941
Query: 194 KSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXAR 253
K E N L K+ ++++ L +++ Q L Q
Sbjct: 942 KEEMNKEITWL---------KEEGVKQDTTLNELQEQ-LKQKSAHVNSLAQDETKLKAHL 991
Query: 254 DKFIANLEEM--KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF---NETMQEKN 308
+K +L + + ++E+L E+K E K+++ L KL EF + ++ N
Sbjct: 992 EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSN 1051
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN 368
L D S + K EL + + E L + + N +LI +K + I S +IS+
Sbjct: 1052 KSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTN--ELINISSSKTNAILS--RISH 1107
Query: 369 QLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL--WEAKKQIADLT 426
C + T + +L + T ++ L Q+ + + N + +A Q+ +
Sbjct: 1108 ---C----QHRTTKVKEALLIKTCT--VSELEAQLRQLTEEQNTLNISFQQATHQLEEKE 1158
Query: 427 EQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEI- 485
Q +K + L TE + L E G N++ + K+S + +
Sbjct: 1159 NQIKSMKADIESLVTEKEALQKE-----GGNQQQAASEKESCITQLKKELSENINAVTLM 1213
Query: 486 -EDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
E++K K +E S + L D+ Q Q + L +
Sbjct: 1214 KEELKEKKVEISSLSKQLTDLNVQLQNSISLSE 1246
Score = 35.1 bits (77), Expect = 0.60
Identities = 51/268 (19%), Positives = 104/268 (38%), Gaps = 20/268 (7%)
Query: 142 ESLEEVALEIDLKKNSIT--KDNISIKTL--LDKLITKNETDINELRNSI-KYLESVKSE 196
+ LE V L + K+ + +D + ++ L +L K E I ++ + +E + +
Sbjct: 1461 KELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1520
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
Y E +LN + ++ + EV +L+ + +++ ++
Sbjct: 1521 YKKGTESHLSELNTKLQER---EREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQE 1577
Query: 257 IANLEEMKTMLVEEKLSEIKE---KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
A+ + EEK+S ++ + E Q + E+ + E QE+ I
Sbjct: 1578 EADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLI---- 1633
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
K+ E + E Q + HL E+L + +N Y LI + ++ + L
Sbjct: 1634 ---KLEHAEAKQHEDQSMIGHLQEELEE-KNKKYSLIVAQHVEKEGGKNNIQAKQNLENV 1689
Query: 374 LDDESENTYERISLTLDKITNHITYLNT 401
DD + E+ LT + I L++
Sbjct: 1690 FDDVQKTLQEK-ELTCQILEQKIKELDS 1716
Score = 33.9 bits (74), Expect = 1.4
Identities = 36/175 (20%), Positives = 79/175 (45%), Gaps = 8/175 (4%)
Query: 175 KNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQ-NCIQE-EVDLLKIENQNL 232
K E + EL+++ L+ + E+NT + ++L + + N QE E +LL+ +
Sbjct: 1835 KQEQEDLELKHN-STLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEET 1893
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEK 292
Q ++ + EE T V + ++++E + ++Q+++ E
Sbjct: 1894 NQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ-EEN 1952
Query: 293 LICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSY 347
D N T+ E L+ + ++ ++ + +E +EQ+ +L ++L E N Y
Sbjct: 1953 PGND----NVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVY 2003
Score = 33.5 bits (73), Expect = 1.8
Identities = 43/211 (20%), Positives = 104/211 (49%), Gaps = 22/211 (10%)
Query: 268 VEEKLSEI-KEKDENFKQEIDMLNEKLICDRREFNETM-QEKNILLSDLSKKVNKTEREL 325
++E+L E+ K KD + ++ ++ + + D + E + Q+K +++++ +++++T L
Sbjct: 178 LDERLQELEKIKDLHMAEKTKLITQ--LRDAKNLIEQLEQDKGMVIAETKRQMHET---L 232
Query: 326 EEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI 385
E K+E++ L ++ +L E + S+ A+ ++ LS ++E ++
Sbjct: 233 EMKEEEIAQLRSRIKQMTTQGEELREQ--KEKSERAAFEELEKALSTA--QKTEEARRKL 288
Query: 386 SLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL----TEQNIILKERLSQLET 441
+D+ I + +E ++ Q L K+++ D+ +E+ I ++L + E
Sbjct: 289 KAEMDEQIKTI----EKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKEL 344
Query: 442 ENK--ELLIEIQT-VRGSNEEVTLNLKDSST 469
K EL ++QT R E++ + L+ S +
Sbjct: 345 ARKEQELTKKLQTREREFQEQMKVALEKSQS 375
Score = 33.1 bits (72), Expect = 2.4
Identities = 48/225 (21%), Positives = 96/225 (42%), Gaps = 14/225 (6%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK----NILLS 312
I LE+ K M++ E ++ E E ++EI L ++ + E ++K
Sbjct: 210 IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE 269
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK---LIENMFNKVSQIASDF--KIS 367
+L K ++ ++ E +++ + EQ+ E S + ++ ++V Q D K S
Sbjct: 270 ELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 329
Query: 368 NQLSCELD--DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQL-LWEAKKQIAD 424
+ +L E E + LT T + +K+ + L + + K+Q
Sbjct: 330 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQES 389
Query: 425 LTEQNIILKERLSQLETENK--ELLIEIQTVRGSNEEVTLNLKDS 467
L + + L+++ E+ENK +L E +T R E+ +L+ S
Sbjct: 390 LALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 434
>BC126409-1|AAI26410.1| 1941|Homo sapiens myosin, heavy chain 2,
skeletal muscle, adult protein.
Length = 1941
Score = 51.6 bits (118), Expect = 6e-06
Identities = 76/395 (19%), Positives = 160/395 (40%), Gaps = 19/395 (4%)
Query: 134 INTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYL 190
I +T E EE+ E+ KK + + +K +D L + K E + + N +K L
Sbjct: 925 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 984
Query: 191 ESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXX 248
+ + KL ++ A+ Q Q+ +D L+ E N L
Sbjct: 985 TEEMAGLDETIAKLTKE-KKAL--QEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLE 1041
Query: 249 XXXARDKFIA-NLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQ 305
++K + +LE K L + KL++ D EN KQ++D +K + ++
Sbjct: 1042 GSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIE 1101
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
++ L L KK+ + + +EE +E++ E L + ++S+ +
Sbjct: 1102 DEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL-EEISERLEEAG 1160
Query: 366 ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL 425
+ E++ + E ++++ L++ T + T + +A + E +QI +L
Sbjct: 1161 GATSAQIEMNKKREAEFQKMRRDLEE----ATLQHEATAATLRKKHADSVAELGEQIDNL 1216
Query: 426 TEQNIILKERLSQLETENKELLIEIQTV---RGSNEEVTLNLKDSSTXXXXXXXXXXXXS 482
L++ S+++ E +L ++TV +G+ E++ L+D +
Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Query: 483 NEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
N++ + ++ +F D + +L GK
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGK 1311
Score = 49.2 bits (112), Expect = 3e-05
Identities = 49/264 (18%), Positives = 112/264 (42%), Gaps = 19/264 (7%)
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---LSKKVNKTERELE 326
++L +K +++N +QEI L E++ + +E + K + + L + + E LE
Sbjct: 1499 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLE 1558
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQLSCELDDESENTYERI 385
++ ++ + +LN ++ + I ++ Q+ + +I + LD E + + I
Sbjct: 1559 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAI 1618
Query: 386 SLT------LDKITNHITYLNTQINETQKN---------DNAQLLWEAKKQIADLTEQNI 430
L L+++ + + N E +N D L +A + DL EQ
Sbjct: 1619 RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLA 1678
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKT 490
+++ R + L+ E +EL ++ S + L D+S N + ++T
Sbjct: 1679 MVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLET 1738
Query: 491 KVMEWKSQFEDLDDVMKQQQKELK 514
+ + + + ED+ + +++ K
Sbjct: 1739 DISQMQGEMEDILQEARNAEEKAK 1762
Score = 48.8 bits (111), Expect = 5e-05
Identities = 48/235 (20%), Positives = 101/235 (42%), Gaps = 9/235 (3%)
Query: 220 EEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD 279
E++D L+ Q L + K NLE+M L E++LSE+K K+
Sbjct: 1211 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTL-EDQLSELKSKE 1269
Query: 280 ENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM 336
E ++ I+ L +L + EF+ + EK L+S LS+ +++EE + QL
Sbjct: 1270 EEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQL---- 1325
Query: 337 EQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHI 396
E+ +N +++ + + ++ + EL ++ K
Sbjct: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDA 1385
Query: 397 TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
++ E +K AQ L A++ + + + L++ +L+ E ++L+++++
Sbjct: 1386 IQRTEELEEAKKK-LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439
Score = 37.5 bits (83), Expect = 0.11
Identities = 37/217 (17%), Positives = 98/217 (45%), Gaps = 6/217 (2%)
Query: 303 TMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
TM+E+ + D ++ K+E + +E +E++ L+++ ND + E + + +
Sbjct: 857 TMKEEFQKIKD---ELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAKKQ 421
K QL ++ + +E + + + +T L + +E +K+ D+ +L ++
Sbjct: 914 LIKTKIQLEAKIKEVTERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEK 972
Query: 422 IADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXX 480
TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 973 EKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIK 1032
Query: 481 XSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+++D++ + + K DL+ ++ + +LKL +
Sbjct: 1033 LEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069
>AK126045-1|BAC86410.1| 978|Homo sapiens galactosaminyltransferase
9 protein.
Length = 978
Score = 51.6 bits (118), Expect = 6e-06
Identities = 106/499 (21%), Positives = 204/499 (40%), Gaps = 43/499 (8%)
Query: 52 AELKND--EINSMIRQLXXXXXXXXXXXXXLTEKLT-IAETKHNDLKKLYEDSASELEAL 108
AEL+ + E N IR L EK I +H +++K E ++LE
Sbjct: 282 AELEQELMEKNEKIRSLETNINTEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKK 341
Query: 109 KRE------NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLK--KNSITK 160
++ + M D++ ++SL ++ T + G E + + LK +N +++
Sbjct: 342 DQQFKEQEKTMSMLQQDIICKQHHLESLDRLL-TESKGEMKKENMKKDEALKALQNQVSE 400
Query: 161 DNISIKTLLDKL-ITKNET--DINELR-NSIKYLESVK--SEYNTANEKLFEQLNNAVDK 214
+ I ++ L L I K E +N+L N K+ + +K SE +K + N+++ +
Sbjct: 401 ETIKVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKSEEVYCLQKELKIKNHSLQE 460
Query: 215 ---QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
QN I + L+ + Q L Q K L++ + E K
Sbjct: 461 TSEQNVILQHT--LQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAE-K 517
Query: 272 LSEIKEKDENFKQEIDMLNEKLI---CDRREFNETMQEKNILLSDLSKKVNKTERELEEK 328
L +++EK E+ E D+ +K+I R+ M + LS + K++ +R+ E K
Sbjct: 518 LRKMEEKCESAAHEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENK 577
Query: 329 Q---EQLTHLMEQLN---DTENNSYKLIENMFNKV-SQIASDFKISNQLSCELDD---ES 378
QL +++Q + + N+ K +E + + +++ + L EL + E
Sbjct: 578 AMHFSQLDMILDQTKTELEKKTNAVKELEKLQHSTETELTEALQKREVLETELQNAHGEL 637
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD----LTEQNIILKE 434
++T ++ D + L+ + T D L E K +I D L E + LKE
Sbjct: 638 KSTLRQLQELRDVLQK--AQLSLEEKYTTIKDLTAELRECKMEIEDEKQELLEMDQALKE 695
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
R +L+ ++ T+R E+ + + +IE + K+
Sbjct: 696 RNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQN 755
Query: 495 WKSQFEDLDDVMKQQQKEL 513
K Q + + +M Q ++E+
Sbjct: 756 AKEQLREKEFIMLQNEQEI 774
Score = 44.0 bits (99), Expect = 0.001
Identities = 69/338 (20%), Positives = 142/338 (42%), Gaps = 29/338 (8%)
Query: 144 LEEVALEIDLKKNSITK--DNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
+ E+ +++ +K+ I K N++ L LIT N++ + +S++ E VK +
Sbjct: 120 ISELRIKLAIKEAEIQKLHANLTANQLSQSLITCNDSQESSKLSSLE-TEPVKLGGHQVA 178
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E + +Q + ++KQ + E Q L+ +A+
Sbjct: 179 ESVKDQNQHTMNKQ---------YEKERQRLVTGIEELRTKLIQIEAENSDLKVNMAH-R 228
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ L++E+L E + E+ +L+ ++ ++EK + S ++ K +
Sbjct: 229 TSQFQLIQEELLEKASNSSKLESEMTKKCSQLLTLEKQ----LEEKIVAYSSIAAKNAEL 284
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV--SQIASDFKISNQLSCELD---- 375
E+EL EK E++ L +N TE+ L K+ Q K +L +L+
Sbjct: 285 EQELMEKNEKIRSLETNIN-TEHEKICLAFEKAKKIHLEQHKEMEKQIERLEAQLEKKDQ 343
Query: 376 --DESENTYERISLTLDKITNHITYLNTQINETQ---KNDNAQLLWEAKKQIADLTEQNI 430
E E T + + +H+ L+ + E++ K +N + K ++E+ I
Sbjct: 344 QFKEQEKTMSMLQQDIICKQHHLESLDRLLTESKGEMKKENMKKDEALKALQNQVSEETI 403
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
+++ S LE +EL++ + + G+ E+ LK S
Sbjct: 404 KVRQLDSALEICKEELVLHLNQLEGNKEKFEKQLKKKS 441
Score = 43.6 bits (98), Expect = 0.002
Identities = 73/416 (17%), Positives = 172/416 (41%), Gaps = 42/416 (10%)
Query: 135 NTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVK 194
+TL + L++ + +++ TK + L +L + E+ +LR + ES
Sbjct: 470 HTLQQQQQMLQQETIRNGELEDTQTKLEKQVSKLEQELQKQRESSAEKLRKMEEKCESAA 529
Query: 195 SEYNTANEKLFE----------QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
E + +K+ E +++ ++ + +++E+ LK + +N
Sbjct: 530 HEADLKRQKVIELTGTARQVKIEMDQYKEELSKMEKEIMHLKRDGENKAMHFSQLDMILD 589
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNE-- 302
+ + LE+++ E +L+E +K E + E+ + +L R+ E
Sbjct: 590 QTKTELEKKTNAVKELEKLQHS-TETELTEALQKREVLETELQNAHGELKSTLRQLQELR 648
Query: 303 --------TMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF 354
+++EK + DL+ ++ + + E+E+++++L + + L + +++L +
Sbjct: 649 DVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDEKQELLEMDQALKE---RNWELKQRAA 705
Query: 355 NKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN----- 409
+V+ + + + + E T E+ L L + I LN ++ ++
Sbjct: 706 -QVTHLDMTIREHRGEMEQKIIKLEGTLEKSELELKECNKQIESLNDKLQNAKEQLREKE 764
Query: 410 ----DNAQLLWEAKKQIAD----LTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVT 461
N Q + + KK+I + E ++KE+ + T+ KE + Q +R + E+V
Sbjct: 765 FIMLQNEQEISQLKKEIERTQQRMKEMESVMKEQEQYIATQCKEAIDLGQKLRLTREQV- 823
Query: 462 LNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
++S T EIE + +++ + K ++ D +EL K
Sbjct: 824 ---QNSHTELAEARHQQVQAQREIERLSSELEDMKQLSKEKDAHGNHLAEELGASK 876
Score = 37.9 bits (84), Expect = 0.085
Identities = 53/249 (21%), Positives = 112/249 (44%), Gaps = 24/249 (9%)
Query: 104 ELEALKR--ENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKD 161
E+ LKR EN MH S + + I+D + TN + LE++ + + +
Sbjct: 566 EIMHLKRDGENKAMHFSQLDM---ILDQTKTELEKKTNAVKELEKLQHSTETELTEALQK 622
Query: 162 NISIKTLLDKL---ITKNETDINELRNSIKYLE-SVKSEYNTANEKLFEQLNNAVDKQNC 217
++T L + + ELR+ ++ + S++ +Y T + E ++ ++
Sbjct: 623 REVLETELQNAHGELKSTLRQLQELRDVLQKAQLSLEEKYTTIKDLTAELRECKMEIEDE 682
Query: 218 IQEEVDL---LKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSE 274
QE +++ LK N L Q ++ I LE T+ EK SE
Sbjct: 683 KQELLEMDQALKERNWELKQRAAQVTHLDMTIREHRGEMEQKIIKLEG--TL---EK-SE 736
Query: 275 IKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTH 334
++ K+ N ++I+ LN+KL + E ++EK ++ +++++ ++E+E Q+++
Sbjct: 737 LELKECN--KQIESLNDKL----QNAKEQLREKEFIMLQNEQEISQLKKEIERTQQRMKE 790
Query: 335 LMEQLNDTE 343
+ + + E
Sbjct: 791 MESVMKEQE 799
>AF111784-1|AAD29950.1| 1941|Homo sapiens myosin heavy chain IIa
protein.
Length = 1941
Score = 51.6 bits (118), Expect = 6e-06
Identities = 76/395 (19%), Positives = 160/395 (40%), Gaps = 19/395 (4%)
Query: 134 INTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYL 190
I +T E EE+ E+ KK + + +K +D L + K E + + N +K L
Sbjct: 925 IKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKEKHATENKVKNL 984
Query: 191 ESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXX 248
+ + KL ++ A+ Q Q+ +D L+ E N L
Sbjct: 985 TEEMAGLDETIAKLTKE-KKAL--QEAHQQTLDDLQAEEDKVNTLTKAKIKLEQQVDDLE 1041
Query: 249 XXXARDKFIA-NLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQ 305
++K + +LE K L + KL++ D EN KQ++D +K + ++
Sbjct: 1042 GSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEFEISNLQSKIE 1101
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
++ L L KK+ + + +EE +E++ E L + ++S+ +
Sbjct: 1102 DEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSREL-EEISERLEEAG 1160
Query: 366 ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL 425
+ E++ + E ++++ L++ T + T + +A + E +QI +L
Sbjct: 1161 GATSAQIEMNKKREAEFQKMRRDLEE----ATLQHEATAATLRKKHADSVAELGEQIDNL 1216
Query: 426 TEQNIILKERLSQLETENKELLIEIQTV---RGSNEEVTLNLKDSSTXXXXXXXXXXXXS 482
L++ S+++ E +L ++TV +G+ E++ L+D +
Sbjct: 1217 QRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSKEEEQQRLI 1276
Query: 483 NEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
N++ + ++ +F D + +L GK
Sbjct: 1277 NDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGK 1311
Score = 49.2 bits (112), Expect = 3e-05
Identities = 49/264 (18%), Positives = 112/264 (42%), Gaps = 19/264 (7%)
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---LSKKVNKTERELE 326
++L +K +++N +QEI L E++ + +E + K + + L + + E LE
Sbjct: 1499 DQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEEAEASLE 1558
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQLSCELDDESENTYERI 385
++ ++ + +LN ++ + I ++ Q+ + +I + LD E + + I
Sbjct: 1559 HEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQSTLDAEIRSRNDAI 1618
Query: 386 SLT------LDKITNHITYLNTQINETQKN---------DNAQLLWEAKKQIADLTEQNI 430
L L+++ + + N E +N D L +A + DL EQ
Sbjct: 1619 RLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLA 1678
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKT 490
+++ R + L+ E +EL ++ S + L D+S N + ++T
Sbjct: 1679 MVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLET 1738
Query: 491 KVMEWKSQFEDLDDVMKQQQKELK 514
+ + + + ED+ + +++ K
Sbjct: 1739 DISQMQGEMEDILQEARNAEEKAK 1762
Score = 48.8 bits (111), Expect = 5e-05
Identities = 48/235 (20%), Positives = 101/235 (42%), Gaps = 9/235 (3%)
Query: 220 EEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD 279
E++D L+ Q L + K NLE+M L E++LSE+K K+
Sbjct: 1211 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTL-EDQLSELKSKE 1269
Query: 280 ENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM 336
E ++ I+ L +L + EF+ + EK L+S LS+ +++EE + QL
Sbjct: 1270 EEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGKQAFTQQIEELKRQL---- 1325
Query: 337 EQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHI 396
E+ +N +++ + + ++ + EL ++ K
Sbjct: 1326 EEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKANTEVAQWRTKYETDA 1385
Query: 397 TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
++ E +K AQ L A++ + + + L++ +L+ E ++L+++++
Sbjct: 1386 IQRTEELEEAKKK-LAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVE 1439
Score = 37.5 bits (83), Expect = 0.11
Identities = 37/217 (17%), Positives = 98/217 (45%), Gaps = 6/217 (2%)
Query: 303 TMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
TM+E+ + D ++ K+E + +E +E++ L+++ ND + E + + +
Sbjct: 857 TMKEEFQKIKD---ELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAKKQ 421
K QL ++ + +E + + + +T L + +E +K+ D+ +L ++
Sbjct: 914 LIKTKIQLEAKIKEVTERAEDEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLAKVEK 972
Query: 422 IADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXX 480
TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 973 EKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTLTKAKIK 1032
Query: 481 XSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+++D++ + + K DL+ ++ + +LKL +
Sbjct: 1033 LEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1069
>AC002563-2|AAB71327.1| 1286|Homo sapiens WUGSC:H_127H14.1 protein.
Length = 1286
Score = 51.6 bits (118), Expect = 6e-06
Identities = 74/412 (17%), Positives = 171/412 (41%), Gaps = 24/412 (5%)
Query: 113 IQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL 172
+Q H + +I+ +IN + + SLE+ +E+ + N + N S+ T +
Sbjct: 20 MQRHEEEAHEKGKILSEQKAMINAMDSKIRSLEQRIVELS-EANKLAA-NSSLFT--QRN 75
Query: 173 ITKNETDINELRNSIKYLESVKSEYNTANEKLFEQL-----NNAVDKQNCIQEEVDLLKI 227
+ E I+ELR YLE+ + N KL EQL + DK ++ E L ++
Sbjct: 76 MKAQEEMISELRQQKFYLETQAGKLEAQNRKLEEQLEKISHQDHSDKNRLLELETRLREV 135
Query: 228 ENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML---VEEKLSEIKEKDENFKQ 284
++ Q R+ + L+ + L + + +E++E ++
Sbjct: 136 SLEHEEQ-KLELKRQLTELQLSLQERESQLTALQAARAALESQLRQAKTELEETTAEAEE 194
Query: 285 EIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTEN 344
EI L +R+F + ++ +++DL +++N+ + E Q +L +QL++
Sbjct: 195 EIQALTAHRDEIQRKF-DALRNSCTVITDLEEQLNQLTEDNAELNNQNFYLSKQLDEASG 253
Query: 345 NSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQIN 404
+ ++++ + ++V + + + +L + + T E + T + + L +
Sbjct: 254 ANDEIVQ-LRSEVDHLRREI---TEREMQLTSQKQ-TMEALKTTCTMLEEQVMDLEALND 308
Query: 405 ETQKNDNAQLLWEAKKQIA--DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL 462
E + + WEA + + + ++ ++E L+TE + Q + S + V L
Sbjct: 309 ELLEKERQ---WEAWRSVLGDEKSQFECRVRELQRMLDTEKQSRARADQRITESRQVVEL 365
Query: 463 NLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+K+ + E + K+ + + + L+ + Q++L+
Sbjct: 366 AVKEHKAEILALQQALKEQKLKAESLSDKLNDLEKKHAMLEMNARSLQQKLE 417
Score = 37.1 bits (82), Expect = 0.15
Identities = 56/278 (20%), Positives = 114/278 (41%), Gaps = 21/278 (7%)
Query: 83 KLTIAETKHNDLKKLYEDSASELE---ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
+LT + L+ + +ELE A E IQ T+ + D+L +T+
Sbjct: 163 QLTALQAARAALESQLRQAKTELEETTAEAEEEIQALTAHRDEIQRKFDALRNSCTVITD 222
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL--ESVKSEY 197
LEE ++ + N + LD+ N+ +I +LR+ + +L E + E
Sbjct: 223 ----LEEQLNQLTEDNAELNNQNFYLSKQLDEASGAND-EIVQLRSEVDHLRREITEREM 277
Query: 198 NTANEKLFEQLNNAVDKQNC--IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
++K Q A+ K C ++E+V L+ N LL+ + +
Sbjct: 278 QLTSQK---QTMEAL-KTTCTMLEEQVMDLEALNDELLEKERQWEAWRSVLGDE---KSQ 330
Query: 256 FIANLEEMKTMLVEEKLSEIK--EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
F + E++ ML EK S + ++ +Q +++ ++ + + ++E+ +
Sbjct: 331 FECRVRELQRMLDTEKQSRARADQRITESRQVVELAVKEHKAEILALQQALKEQKLKAES 390
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIE 351
LS K+N E++ + L ++L +L+E
Sbjct: 391 LSDKLNDLEKKHAMLEMNARSLQQKLETERELKQRLLE 428
>AB053470-1|BAC54109.1| 1088|Homo sapiens ELKS delta protein.
Length = 1088
Score = 51.6 bits (118), Expect = 6e-06
Identities = 97/470 (20%), Positives = 197/470 (41%), Gaps = 35/470 (7%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
+TV E+K+ +I+SM R L + E + ++K++ E S + +
Sbjct: 381 QTVIEMKDSKISSMERGLRDLEEEIQMLK---SNGALSTEEREEEMKQM-EVYRSHSKFM 436
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSIT-KDNIS--I 165
K + Q+ E++ +L + TLTN F ++ I++ K S+T K+ + +
Sbjct: 437 KNKIGQVKQELSRKDTELL-ALQTKLETLTNQFSDSKQ---HIEVLKESLTAKEQRAAIL 492
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLL 225
+T +D L + E L K ++ + E T ++ + L + +D + + +V++L
Sbjct: 493 QTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHD-LKDMLDVK---ERKVNVL 548
Query: 226 KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQE 285
+ + +NL + + N + T L EE L+E + E K++
Sbjct: 549 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL-EEALAEKERTIERLKEQ 607
Query: 286 IDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN 345
D D RE E + L DL +KV+ + +L EK+ L L E + ++
Sbjct: 608 RDR-------DEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS 660
Query: 346 SYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
K + K +IA + K L E + + + ++++ I +L +I
Sbjct: 661 GLKKDSRL--KTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI-- 716
Query: 406 TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
T+ D + +A+ ++ L E ILKE ++ ++K++ + V+ N++V NLK
Sbjct: 717 TRYKDESS---KAQAEVDRLLE---ILKEVENEKNDKDKKIAELERQVKDQNKKVA-NLK 769
Query: 466 DSSTXXXXXXXXXXXXSNEIED-MKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ ED + + + DD +++ ++ L+
Sbjct: 770 HKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALR 819
Score = 44.0 bits (99), Expect = 0.001
Identities = 66/358 (18%), Positives = 141/358 (39%), Gaps = 17/358 (4%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++LEE+ L I+ +K ++ + SIK LL+ L +K + + + ++E + +
Sbjct: 286 KTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHH 345
Query: 202 -EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L EQ +K+N + E + EN + ++ + +L
Sbjct: 346 LESLLEQ----KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDL 401
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDR-REFNETMQEKNILLSDLSKKV 318
EE ML +E++E KQ E+ + K + ++ + + + K+ L L K+
Sbjct: 402 EEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKL 461
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ + ++ + L E L E + L + ++ + N+ + ++ D +
Sbjct: 462 ETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA 521
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
E + + + + + ++N QK + ++Q+ D +Q LKER+
Sbjct: 522 EEKGTQAG-EIHDLKDMLDVKERKVNVLQKK-----IENLQEQLRDKEKQMSSLKERVKS 575
Query: 439 LE---TENKELLIEIQTVRGSNEEVTLNLKDS-STXXXXXXXXXXXXSNEIEDMKTKV 492
L+ T L ++ E LK+ +++D+K KV
Sbjct: 576 LQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKV 633
Score = 44.0 bits (99), Expect = 0.001
Identities = 51/225 (22%), Positives = 88/225 (39%), Gaps = 12/225 (5%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVK---SEYN 198
E L+EV E + K I + +K K+ + E + S + LE + N
Sbjct: 735 EILKEVENEKNDKDKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLN 794
Query: 199 TANEKLFEQLNNAVDK----QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
++++L + L D+ + ++E V + L Q A +
Sbjct: 795 DSSQQLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAME 854
Query: 255 KFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDM-LNEKLICDRREFNETMQEK--NI 309
K LE MK L ++ L+E + N + E L E L + + EK NI
Sbjct: 855 KVKQELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANI 914
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF 354
L +LS KT+ E+ + + L++QL N KL+ + +
Sbjct: 915 ALLELSSSKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNY 959
Score = 33.5 bits (73), Expect = 1.8
Identities = 50/200 (25%), Positives = 82/200 (41%), Gaps = 18/200 (9%)
Query: 48 DKTVAELKND--EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSA--- 102
DK +AEL+ + N + L + E+ E ND + +DS
Sbjct: 748 DKKIAELERQVKDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKK 807
Query: 103 ----SELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
ELE RE++Q+ MV+ + + T + ++E+V E++ K +
Sbjct: 808 DDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKL 867
Query: 159 TKDNISI---KTLLDKLITKNETDINE-LRNSIKYLESVKSEYNTANEKLFEQLNNAVDK 214
+ S+ +T L L + + E L + L + SE AN L E L+++ K
Sbjct: 868 SSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISE-KDANIALLE-LSSSKKK 925
Query: 215 QNCIQEEVDLLKIENQNLLQ 234
QEEV LK E L+Q
Sbjct: 926 ---TQEEVAALKREKDRLVQ 942
>X95654-1|CAA64956.1| 976|Homo sapiens polypeptide of 976 aa
protein.
Length = 976
Score = 51.2 bits (117), Expect = 9e-06
Identities = 93/442 (21%), Positives = 180/442 (40%), Gaps = 54/442 (12%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
EK E + + +++Y D + +E + I H ++ V E +S E+ L +
Sbjct: 195 EKTKKYEYEREETRQVYMDLNNNIEKM----ITAH-GELRVQAE--NSRLEMHFKLKEDY 247
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E ++ LE + KK K+ + LL + IT+ E N++++ LE + + N
Sbjct: 248 EKIQH--LEQEYKKEINDKEK-QVSLLLIQ-ITEKE---NKMKDLTFLLEESRDKVNQLE 300
Query: 202 EKL---FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
EK E L +++KQ+ + +E++ +K+ Q + K I
Sbjct: 301 EKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQIAT-------KTIC 353
Query: 259 NL-EEMKTMLVEEKLSEIKEKD--ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
L EE +T + E + F+ + L E L +++ + + IL +L
Sbjct: 354 QLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQ 413
Query: 316 KKVNKTERELE---EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSC 372
KK ++ E + K+ +L L + L + E Y+ F K IA + K + Q
Sbjct: 414 KKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYE--NKQFEK---IAEELKGTEQELI 468
Query: 373 ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL 432
L E + + L IT Y + ++ + K ++ + +N L
Sbjct: 469 GLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL------------KTELENEKLKNTEL 516
Query: 433 KERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKV 492
++L ENKEL E ++TL LK+ +IE+++
Sbjct: 517 TSHCNKLSLENKELTQE-------TSDMTLELKNQQEDINNNKKQEERMLKQIENLQETE 569
Query: 493 MEWKSQFEDLDDVMKQQQKELK 514
+ +++ E + + +KQ++ E+K
Sbjct: 570 TQLRNELEYVREELKQKRDEVK 591
Score = 43.2 bits (97), Expect = 0.002
Identities = 84/394 (21%), Positives = 160/394 (40%), Gaps = 28/394 (7%)
Query: 89 TKHNDLKKLYEDSASELE-ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
T H +L+ E+S E+ LK + ++ + EI D +V L E ++
Sbjct: 223 TAHGELRVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKM 282
Query: 148 ALEIDLKKNSITKDN-ISIKTLLDKLITKN-ETDINELRNSIKYLESVKS--EYNTANEK 203
L + S K N + KT KL ++N + I + + K LE +K + + + +K
Sbjct: 283 KDLTFLLEESRDKVNQLEEKT---KLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQK 339
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
E+ K C E ++E N + + E+
Sbjct: 340 ALEEDLQIATKTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEE---LLRTEQQ 396
Query: 264 KTMLVEEKLS----EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
+ E++L E+++K ++ + N K + + E + + EK LL + +K+
Sbjct: 397 RLEKNEDQLKILTMELQKKSSELEEMTKLTNNKEV-ELEELKKVLGEKETLLYE-NKQFE 454
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES- 378
K EL+ +++L L+ Q + E + ++ Q S K L EL++E
Sbjct: 455 KIAEELKGTEQELIGLL-QAREKEVHDLEIQLTAITTSEQYYS--KEVKDLKTELENEKL 511
Query: 379 ENTY-----ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAK--KQIADLTEQNII 431
+NT ++SL ++T + + ++ Q++ N E + KQI +L E
Sbjct: 512 KNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDINNNKKQEERMLKQIENLQETETQ 571
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
L+ L + E K+ E++ +EE NL+
Sbjct: 572 LRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Score = 31.1 bits (67), Expect = 9.8
Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 8/162 (4%)
Query: 298 REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV 357
+E N T N+L ++ KT++ E++E M D NN K+I ++
Sbjct: 174 KENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM----DLNNNIEKMI-TAHGEL 228
Query: 358 SQIASDFKISNQLSCELDDES-ENTYERISLTLDKITNHITYLNTQINETQK--NDNAQL 414
A + ++ + D E ++ + ++ ++ L QI E + D L
Sbjct: 229 RVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL 288
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
L E++ ++ L E+ + E L Q + L E++ ++ S
Sbjct: 289 LEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVS 330
>X03740-1|CAA27380.1| 876|Homo sapiens protein ( Human skeletal
mRNA for myosin heavy chain light meromyosin region. ).
Length = 876
Score = 51.2 bits (117), Expect = 9e-06
Identities = 77/427 (18%), Positives = 175/427 (40%), Gaps = 39/427 (9%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVMV--------VPEIIDSLTEVINTLTNGFES 143
+K YE+S +LE LKRE N+Q SD+ + E+ +V + +
Sbjct: 425 IKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAA 484
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLDKLITKNETDINEL-RNSIKYLESVKSEYNT 199
LEE ++ ++ I + + +K+ +D+ I + + +I+++ RN I+ ES++S N
Sbjct: 485 LEEAEASLEHEEGKILRIQLEVNQVKSEVDRKIAEKDEEIDQMKRNHIRIEESMQSTLNA 544
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
+ + + + E L N+ + D + +
Sbjct: 545 EIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEDLRNYQNTQAILKDTQLHLDDALRS 604
Query: 260 LEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
E++K L VE + + ++ + E + ++ +E + + +L + +
Sbjct: 605 QEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSL 664
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE 377
+N T+++LE Q+ ME + N+ + + + +A + K S L
Sbjct: 665 IN-TKKKLETDISQIQGEMEDIIKEARNAEEKAKKAITDAAMMAEELKKEQDTSAHL--- 720
Query: 378 SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLS 437
ER+ L++ + + +++E ++ L KKQI L + ++E
Sbjct: 721 -----ERMKKNLEQTVKDLQH---RLDEAEQ----LALKGGKKQIQKLEAK---VRELEG 765
Query: 438 QLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKS 497
++E+E K ++ V+G ++ +K+ + + ++ ++ KV +K
Sbjct: 766 EVESEQKR---NVEAVKGLHKH-ERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKR 821
Query: 498 QFEDLDD 504
Q E+ ++
Sbjct: 822 QAEEAEE 828
Score = 48.0 bits (109), Expect = 8e-05
Identities = 72/369 (19%), Positives = 157/369 (42%), Gaps = 43/369 (11%)
Query: 149 LEIDLKKNSITKDNISIK-TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ 207
L ID+++ + + K T DK++ + + E LES + E + + +LF+
Sbjct: 369 LMIDVERTNAACAALDKKQTNFDKILAEWKQKCEETH---AVLESFQKESRSLSTELFK- 424
Query: 208 LNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML 267
+ NA ++ ++++ LK EN+NL Q K I LE++K +
Sbjct: 425 IKNAYEES---LDQLETLKRENKNLQQEISDLTEQIAEGG-------KRIHELEKIKKQV 474
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEE 327
+EK SE++ E + ++ K++ + E N+ + S++ +K+ + + E+++
Sbjct: 475 EQEK-SELQAALEEAEASLEHEEGKILRIQLEVNQ-------VKSEVDRKIAEKDEEIDQ 526
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
+ + E + T N + + ++ D N++ +L+ + E +
Sbjct: 527 MKRNHIRIEESMQSTLNAEIRSRNDAIRLKKKMEGDL---NEMEIQLNHANRMAAEDLR- 582
Query: 388 TLDKITNHITYLNTQ--INETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
Y NTQ + +TQ + L +A + DL EQ +++ R + L+ E +E
Sbjct: 583 ---------NYQNTQAILKDTQLH-----LDDALRSQEDLKEQLAMVERRANLLQAEIEE 628
Query: 446 LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDV 505
L ++ S + L D+S N + ++T + + + + ED+
Sbjct: 629 LRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIIKE 688
Query: 506 MKQQQKELK 514
+ +++ K
Sbjct: 689 ARNAEEKAK 697
Score = 46.4 bits (105), Expect = 2e-04
Identities = 48/235 (20%), Positives = 104/235 (44%), Gaps = 9/235 (3%)
Query: 220 EEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD 279
E++D L+ Q L + K NLE+M L E++LSEIK K+
Sbjct: 146 EQIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRAL-EDQLSEIKTKE 204
Query: 280 ENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM 336
E ++ I+ L +L ++ E++ + EK+ L + LS+ +++EE + QL
Sbjct: 205 EEQQRLINDLTAQRARLQQNQVEYSRQLDEKDTLETQLSRGKQAFTQQIEELKRQLE--- 261
Query: 337 EQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHI 396
E++ ++ L ++ + + ++ + EL ++ K
Sbjct: 262 EEIKAKSALAHAL-QSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDA 320
Query: 397 TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
++ E +K AQ L +A++ + + + L++ +L+ E ++L+I+++
Sbjct: 321 IQRTEELEEAKKK-LAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVE 374
Score = 40.7 bits (91), Expect = 0.012
Identities = 60/347 (17%), Positives = 145/347 (41%), Gaps = 20/347 (5%)
Query: 161 DNIS-IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQ 219
DN+ +K L+K ++ + +I++L ++++ + K L +QL+ K+ Q
Sbjct: 149 DNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEEQQ 208
Query: 220 EEVDLLKIE----NQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE--KLS 273
++ L + QN ++ + F +EE+K L EE S
Sbjct: 209 RLINDLTAQRARLQQNQVEYSRQLDEKDTLETQLSRGKQAFTQQIEELKRQLEEEIKAKS 268
Query: 274 EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLT 333
+ ++ + + D+L E+ ++ E + + S++++ K E + ++ E+L
Sbjct: 269 ALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELE 328
Query: 334 HLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKIT 393
++L ++ + +E + K + + K +L E++D + ER + +
Sbjct: 329 EAKKKLAQRLQDAEEHVEAVNAKCASLE---KTKQRLQNEVEDLMIDV-ERTNAACAALD 384
Query: 394 NHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTV 453
T + + E + Q E + +++ L L +++ +E L +++T+
Sbjct: 385 KKQTNFDKILAEWK-----QKCEETHAVLESFQKESRSLSTELFKIKNAYEESLDQLETL 439
Query: 454 RGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
+ N+ NL+ + +E+E +K +V + KS+ +
Sbjct: 440 KRENK----NLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQ 482
Score = 39.5 bits (88), Expect = 0.028
Identities = 44/251 (17%), Positives = 107/251 (42%), Gaps = 9/251 (3%)
Query: 271 KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
KL++ D EN KQ++D +K + ++++ L L KK+ + + +EE +
Sbjct: 1 KLAQESAMDIENDKQQLDEKLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELE 60
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
E++ E L + ++S+ + + E++ + E ++++ L
Sbjct: 61 EEIEAERTSRAKAEKLRSDLSREL-EEISERLEEAVGATSTQIEMNKKREAEFQKMRRDL 119
Query: 390 DKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIE 449
++ T + T + +A + E +QI +L L++ S+++ E +L
Sbjct: 120 EE----ATLQHEATAATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEMKMEIDDLASN 175
Query: 450 IQTV---RGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVM 506
++TV +G+ E++ L+D + N++ + ++ + + ++ D
Sbjct: 176 METVSKAKGNLEKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQQNQVEYSRQLDEK 235
Query: 507 KQQQKELKLGK 517
+ +L GK
Sbjct: 236 DTLETQLSRGK 246
>BC038515-1|AAH38515.1| 796|Homo sapiens CCDC110 protein protein.
Length = 796
Score = 51.2 bits (117), Expect = 9e-06
Identities = 68/324 (20%), Positives = 139/324 (42%), Gaps = 16/324 (4%)
Query: 195 SEYNTANEKL---FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXX 251
S+ N+ E+ + L N + + IQ++V L+ EN NL
Sbjct: 378 SKVNSVTEQCVAKIQYLQNYLKESVQIQKKVMELESENLNLKSKMKPLIFTTQSLIQKVE 437
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+K + NL E K+ ++ KLS+ +E + +E + K + + N+T++EKNI L
Sbjct: 438 TYEKQLKNLVEEKST-IQSKLSKTEEYSKECLKEFKKIISKYNVLQGQ-NKTLEEKNIQL 495
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
S +++ + +L+ K+ + M +N+ N +E M + I + ++ + +
Sbjct: 496 SLEKQQMMEALDQLKSKEHKTQSDMAIVNNENNRMSIEMEAMKTNILLIQDEKEMLEKKT 555
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL--TEQN 429
+L E + + + +I ++ +T++ Q++ K + +L T Q
Sbjct: 556 HQLLKEKSSLGNELKESQLEIIQ--LKEKERLAKTEQETLLQIIETVKDEKLNLETTLQE 613
Query: 430 IILKERLSQLETENKELLIEIQTVRGSNEEVTL-NLKDSSTXXXXXXXXXXXXSNEIEDM 488
++ + E EN IQT + + EE L +K++ + E E +
Sbjct: 614 STAARQIMEREIEN------IQTYQSTAEENFLQEIKNAKSEASIYKNSLSEIGKECEML 667
Query: 489 KTKVMEWKSQFEDLDDVMKQQQKE 512
VME K+ + L + +K+ +E
Sbjct: 668 SKMVMETKTDNQILKEELKKHSQE 691
>BC028419-1|AAH28419.1| 833|Homo sapiens coiled-coil domain
containing 110 protein.
Length = 833
Score = 51.2 bits (117), Expect = 9e-06
Identities = 68/324 (20%), Positives = 139/324 (42%), Gaps = 16/324 (4%)
Query: 195 SEYNTANEKL---FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXX 251
S+ N+ E+ + L N + + IQ++V L+ EN NL
Sbjct: 415 SKVNSVTEQCVAKIQYLQNYLKESVQIQKKVMELESENLNLKSKMKPLIFTTQSLIQKVE 474
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+K + NL E K+ ++ KLS+ +E + +E + K + + N+T++EKNI L
Sbjct: 475 TYEKQLKNLVEEKST-IQSKLSKTEEYSKECLKEFKKIISKYNVLQGQ-NKTLEEKNIQL 532
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
S +++ + +L+ K+ + M +N+ N +E M + I + ++ + +
Sbjct: 533 SLEKQQMMEALDQLKSKEHKTQSDMAIVNNENNRMSIEMEAMKTNILLIQDEKEMLEKKT 592
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL--TEQN 429
+L E + + + +I ++ +T++ Q++ K + +L T Q
Sbjct: 593 HQLLKEKSSLGNELKESQLEIIQ--LKEKERLAKTEQETLLQIIETVKDEKLNLETTLQE 650
Query: 430 IILKERLSQLETENKELLIEIQTVRGSNEEVTL-NLKDSSTXXXXXXXXXXXXSNEIEDM 488
++ + E EN IQT + + EE L +K++ + E E +
Sbjct: 651 STAARQIMEREIEN------IQTYQSTAEENFLQEIKNAKSEASIYKNSLSEIGKECEML 704
Query: 489 KTKVMEWKSQFEDLDDVMKQQQKE 512
VME K+ + L + +K+ +E
Sbjct: 705 SKMVMETKTDNQILKEELKKHSQE 728
>AK127744-1|BAC87110.1| 600|Homo sapiens protein ( Homo sapiens
cDNA FLJ45844 fis, clone OCBBF2003518. ).
Length = 600
Score = 51.2 bits (117), Expect = 9e-06
Identities = 67/314 (21%), Positives = 134/314 (42%), Gaps = 25/314 (7%)
Query: 149 LEIDLKKNSITKDNISIKTLL-DKLITKNETDINELRNSIKYLESVKSEYNTAN-EKLFE 206
L ++ KN + ++ ++K +L DKL T N+ +I L++ ++ KSE + E L
Sbjct: 30 LNLEEDKNQLQQELENLKEVLEDKLNTANQ-EIGHLQDMVR-----KSEQGLGSAEGLIA 83
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
L D Q +Q E+DL K +L + ++ IA ++E + +
Sbjct: 84 SLQ---DSQERLQNELDLTK---DSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKL 137
Query: 267 LVEEKLSEIKEK-DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
V++ +++ K EN +QE L E+L E ++ + + L D K +
Sbjct: 138 KVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAAR----- 192
Query: 326 EEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI 385
+ Q+++ L+ Q++ + N + + Q+ + F Q + +E E +++
Sbjct: 193 DSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQR 252
Query: 386 SLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
+L + H+ T E +K A +K A+L +E + E ++
Sbjct: 253 HKSLKEA--HVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQ 310
Query: 446 LLIEIQTVRGSNEE 459
E+QT+R E+
Sbjct: 311 ---ELQTLRFELED 321
>AJ131693-1|CAB40713.1| 3908|Homo sapiens AKAP450 protein protein.
Length = 3908
Score = 51.2 bits (117), Expect = 9e-06
Identities = 72/307 (23%), Positives = 139/307 (45%), Gaps = 26/307 (8%)
Query: 173 ITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL 232
IT NE I + +I L + N+ EKL E+L ++++ +Q +++ L E
Sbjct: 481 ITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFS 540
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLV--EEKLSEIKEKDE----NFKQEI 286
+ K ++ +E++K +V E E++ K E N+K ++
Sbjct: 541 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 600
Query: 287 DMLNEK--LICDR-REFNETMQEK---NILLS---DLSKKVNKTERE----LEEKQEQL- 332
+ML ++ + DR E E E+ +L S +LSK E E +E+ ++ L
Sbjct: 601 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLG 660
Query: 333 THLMEQLNDTENNSYKLIENM-FNKVSQIASDFKISNQLS--CELDDESENT-YERISLT 388
H +Q++ +N + IE M F K + I ++ ++S +L N+ E ++L
Sbjct: 661 IHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ 720
Query: 389 LDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++++ I L + E T + + +L + + + E+ L+E+ +QLE EN L
Sbjct: 721 INELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSIL 780
Query: 447 LIEIQTV 453
E +T+
Sbjct: 781 KDEKKTL 787
Score = 51.2 bits (117), Expect = 9e-06
Identities = 92/391 (23%), Positives = 176/391 (45%), Gaps = 47/391 (12%)
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMV-VPEIIDSLTEVINTLTNGFESLEEVALEI 151
+L KL ED LE R NI+ ++ + + ID L N ++ E+++ +
Sbjct: 636 ELSKLKED----LEIEHRINIEKLKDNLGIHYKQQIDGLQ---NEMSQKIETMQFEKDNL 688
Query: 152 DLKKNSITKDNISIKTLLDKLI-TKNET---DINELRNSIKYLESVKSEYNTANEKLFE- 206
K+N + + +K L L+ +K+E INEL+ I+ L + E T +++ E
Sbjct: 689 ITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL 748
Query: 207 QLNNAV------DKQNCIQEEVDLLKIENQNLL-QXXXXXXXXXXXXXXXXXARDKFIAN 259
QL + +K+N +QE+ L+ EN L + R F+ +
Sbjct: 749 QLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDS 808
Query: 260 LEEMKTMLVEEKLSEIK-EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
++ V EK EI E++E+ KQ+ LNE++ R F + EKN +V
Sbjct: 809 IKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTF--SFAEKNF-------EV 859
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENN---SYKLIENMFNKVSQIASDFKISNQLSCELD 375
N +EL+E+ L + + L D++N YK N+ + + ++ +
Sbjct: 860 N--YQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 917
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKER 435
DE + T+ +L + ++ T T++ E + + L E ++++DL+EQ LK +
Sbjct: 918 DE-DKTFVAETLEMGEVVEKDT---TELMEKLEVTKREKL-ELSQRLSDLSEQ---LKPK 969
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
++ N+ E+++++ E V+L ++
Sbjct: 970 PGEISFLNE----EVKSLKPEKEPVSLRCRE 996
Score = 46.4 bits (105), Expect = 2e-04
Identities = 37/190 (19%), Positives = 95/190 (50%), Gaps = 15/190 (7%)
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQE 330
+L E++++++ FK +++ L + + + Q++++L ++ + + E E+++ E
Sbjct: 2244 RLQELEQENKLFKDDMEKLG---LAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNE 2300
Query: 331 QLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK-ISNQLSCELDDESENTYERISLTL 389
Q+T L +QL T +N K+IE + + + + + + C + E E+++ +
Sbjct: 2301 QVTKLQQQLKITTDN--KVIEEKNELIRDLETQIECLMSDQEC-VKRNREEEIEQLNEVI 2357
Query: 390 DKITNHITYL--NTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL 447
+K+ + + T +N ++ A L K Q+ + + + L++ Q+ET N+E+
Sbjct: 2358 EKLQQELANIGQKTSMNAHSLSEEADSL---KHQLDVVIAEKLALEQ---QVETANEEMT 2411
Query: 448 IEIQTVRGSN 457
++ +N
Sbjct: 2412 FMKNVLKETN 2421
Score = 45.2 bits (102), Expect = 6e-04
Identities = 56/335 (16%), Positives = 145/335 (43%), Gaps = 22/335 (6%)
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
LE + E+ K++ I + N ++ + T+ + E +IK + + ++ ++
Sbjct: 157 LEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQ 216
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNL-LQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ + + + + E+ L+I+ Q L A+ + + + ++
Sbjct: 217 ARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQ 276
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC-----DRREFN---ETMQEKNILLSDL 314
++ + L + ++K E+F +I L EK+ D++ N E +QEK ++ +L
Sbjct: 277 LEEQ--DHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 334
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ K+ + E++ E +++LT + L + + + + + N ++ + + Q S E+
Sbjct: 335 NTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEI 394
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII--- 431
+ T E L K + + T I + + + + L + + ++ ++ Q I+
Sbjct: 395 -KQLMGTVEE----LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMK 449
Query: 432 ---LKERLSQLETENKELLIEIQTVRGSNEEVTLN 463
+++ ++Q+E E++ S +T+N
Sbjct: 450 QELIRQHMAQMEEMKTRHKGEMENALRSYSNITVN 484
Score = 40.3 bits (90), Expect = 0.016
Identities = 50/214 (23%), Positives = 94/214 (43%), Gaps = 17/214 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQE---KNILLSDLSKK 317
+E + +EE+L + +E+ EN +E+ L+ +L ++E +QE +N L D +K
Sbjct: 2202 KEKEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEK 2261
Query: 318 VNKTERELEEKQEQLTHLM----EQLNDTENNSYKLIENMFNKVSQ---IASDFKI---S 367
+ +E + Q H++ Q+ + + K+ Q I +D K+
Sbjct: 2262 LGLAIKESDAMSTQDQHVLFGKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEK 2321
Query: 368 NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE 427
N+L +L+ + E I LN I + Q+ + A + + L+E
Sbjct: 2322 NELIRDLETQIECLMSDQECVKRNREEEIEQLNEVIEKLQQ-ELANIGQKTSMNAHSLSE 2380
Query: 428 QNIILKERLSQLETENKELLIEIQTVRGSNEEVT 461
+ LK +L + E +L +E Q V +NEE+T
Sbjct: 2381 EADSLKHQLDVVIAE--KLALE-QQVETANEEMT 2411
Score = 36.3 bits (80), Expect = 0.26
Identities = 74/344 (21%), Positives = 146/344 (42%), Gaps = 35/344 (10%)
Query: 127 IDSLTEVINTLTN-GFE-SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR 184
+ SL + + T+T+ G E S+ +V + + +D +S + + +K E I +
Sbjct: 1016 VSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHL 1075
Query: 185 NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
S+ S+++ + N+KL ++LN +QN ++ L++E Q +
Sbjct: 1076 PSVTKESSLRATQPSENDKLQKELNVLKSEQNDLR-----LQMEAQRICLSLVYSTHVDQ 1130
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
+DK + +L+E EEK+ E+ Q+I L E +E +
Sbjct: 1131 VREYMENEKDKALCSLKEELIFAQEEKIKEL--------QKIHQL-ELQTMKTQETGDEG 1181
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+ ++L+ L K V+ EE L L L + + K N +K + + D+
Sbjct: 1182 KPLHLLIGKLQKAVS------EECSYFLQTLCSVLGEYYTPALKCEVNAEDK--ENSGDY 1233
Query: 365 KISNQLSCELDD---ESENTYERISLTLDKIT---NHITYLNTQINET--QKNDNAQLLW 416
IS EL D E ++ E + L+K+T N + L T++++ Q+ D +L +
Sbjct: 1234 -ISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEF 1292
Query: 417 EAKKQIADLTEQNIILKE--RLSQLETENKELLIEIQTVRGSNE 458
+ + TE I + L ++ +K L +Q + + +
Sbjct: 1293 GEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKQ 1336
Score = 36.3 bits (80), Expect = 0.26
Identities = 41/161 (25%), Positives = 82/161 (50%), Gaps = 11/161 (6%)
Query: 260 LEEMKTMLVEEKLSEIKEK-DENFKQEIDMLN--EKLICDRREFNETMQEKNILLSDLSK 316
L+E++ L EEK S I E +E K ++D L +++ DR+ +T+Q + ++ K
Sbjct: 3346 LKELQKQL-EEKHSRIVELLNETEKYKLDSLQTRQQMEKDRQVHRKTLQTEQEANTEGQK 3404
Query: 317 KVNKTERELEEKQEQLTHLMEQLN--DTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
K+++ + ++E+ Q QL +Q+ D E + I F K + + S ++ +
Sbjct: 3405 KMHELQSKVEDLQRQLEEKRQQVYKLDLEGQRLQGIMQEFQKQELEREEKRESRRILYQN 3464
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL 415
+E T+ SLT D+ N + + ET++++ A+L+
Sbjct: 3465 LNE-PTTW---SLTSDRTRNWVLQQKIE-GETKESNYAKLI 3500
Score = 33.1 bits (72), Expect = 2.4
Identities = 16/82 (19%), Positives = 45/82 (54%), Gaps = 2/82 (2%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
EE + + + +++ +++ D N K ++ L + + ++ E +QE L+S L +++ +
Sbjct: 1300 EETEFLSIHSQMTNLEDIDVNHKSKLSSLQD--LEKTKQLEEQVQELESLISSLQQQLKE 1357
Query: 321 TERELEEKQEQLTHLMEQLNDT 342
TE+ E + L ++ ++++
Sbjct: 1358 TEQNYEAEIHCLQKRLQAVSES 1379
Score = 33.1 bits (72), Expect = 2.4
Identities = 56/270 (20%), Positives = 116/270 (42%), Gaps = 24/270 (8%)
Query: 210 NAVDKQNCIQEEVDLLKIENQ---NLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+AV NC+++ + +E Q LQ + I E ++
Sbjct: 3057 DAVGLLNCLEQRIQEQGVEYQAAMECLQKADRRSLLSEIQALHAQMNGRKITLKREQESE 3116
Query: 267 LVEEKLSE--IKEKDENF-KQEIDMLNEKLICDRR-EFNETMQEKNILLSDLSKKVNKTE 322
++L E I++K + ++++ + K DR E E + + +++++L ++ +T+
Sbjct: 3117 KPSQELLEYNIQQKQSQMLEMQVELSSMK---DRATELQEQLSSEKMVVAELKSELAQTK 3173
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
ELE + +++L + + +AS+ K S +L L+ E
Sbjct: 3174 LELETTLKAQHKHLKELEAFRLEVKDKTDEVHLLNDTLASEQKKSRELQWALEKEKA--- 3230
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQL--LWEAKKQIADLTEQNI-----ILKER 435
++ + ++ + L + E+QK N QL L E +KQ+ + ++Q I + +
Sbjct: 3231 -KLGRSEERDKEELEDLKFSL-ESQKQRNLQLNLLLEQQKQLLNESQQKIESQRMLYDAQ 3288
Query: 436 LSQLETENKEL--LIEIQTVRGSNEEVTLN 463
LS+ + N EL L+E + VR TL+
Sbjct: 3289 LSEEQGRNLELQVLLESEKVRIREMSSTLD 3318
Score = 32.7 bits (71), Expect = 3.2
Identities = 73/378 (19%), Positives = 162/378 (42%), Gaps = 31/378 (8%)
Query: 80 LTEKLTI---AETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINT 136
+ EKL + AE +DL+K + ++E I++ + ++ +
Sbjct: 2003 MKEKLEVQCQAEKVRDDLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQ 2062
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
L + L+E A++ + +++ ++ ++ L + ++ R + +K +
Sbjct: 2063 LEKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQTREVEQLANHLKEK 2122
Query: 197 YNTANEKLF--EQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD 254
+ +E L EQL + ++N EE++ L+ + L Q
Sbjct: 2123 TDKCSELLLSKEQLQRDIQERN---EEIEKLEFRVRELEQALLVSADTFQKVEDR----- 2174
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF---NETMQEKNILL 311
K +E + +E +L ++ + ++EI L E+L R E NE +Q+ ++ L
Sbjct: 2175 KHFGAVEAKPELSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNEEVQQLHMQL 2234
Query: 312 SDLSKKVNKTE-RELEEKQEQLTHLMEQLN----DTENNSYKLIENMFNKVSQIASDFKI 366
++ KK + T +ELE++ + ME+L +++ S + +F K +QI + ++
Sbjct: 2235 -EIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLFGKFAQIIQEKEV 2293
Query: 367 SNQLSCELDDESENTYERISLTLD-KITNH----ITYLNTQINETQKNDNAQLLWEAKKQ 421
+L+++ +++ +T D K+ I L TQI E +D + +++
Sbjct: 2294 EID---QLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQI-ECLMSDQECVKRNREEE 2349
Query: 422 IADLTEQNIILKERLSQL 439
I L E L++ L+ +
Sbjct: 2350 IEQLNEVIEKLQQELANI 2367
Score = 32.3 bits (70), Expect = 4.2
Identities = 78/413 (18%), Positives = 174/413 (42%), Gaps = 29/413 (7%)
Query: 123 VPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINE 182
V +++++++E + L + + E+ E +K T+ + L ++L ++ +
Sbjct: 1855 VEKLLEAISETSSQLEHAKVTQTELMRESFRQKQEATESLKCQEELRERLHEESRAR-EQ 1913
Query: 183 LRNSIKYLESVKSEY---NTANEKLFEQLNNAVDKQN----CIQEEVDLLKIENQNLLQX 235
L + E V Y T E+ ++ + +D+ C + L+ E Q + +
Sbjct: 1914 LAVELSKAEGVIDGYADEKTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEE 1973
Query: 236 XXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC 295
++ + L+E + L++EKL E++ + E + ++ + L
Sbjct: 1974 RELLSRQKEAMKAEAGPVEQQL--LQETEK-LMKEKL-EVQCQAEKVRDDLQKQVKALEI 2029
Query: 296 DRRE----FNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL---MEQLNDTENNSYK 348
D E F E QEKN L DL ++ E++LE+ ++ L E D +
Sbjct: 2030 DVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDREHERDVFQQEIQ 2089
Query: 349 LIENMFNKVS--QIASDFKIS--NQLSCELDDESENTYERISLTLDKITNHITYLNTQIN 404
+E V Q S+ + QL+ L ++++ E + L+ +++ I N +I
Sbjct: 2090 KLEQQLKVVPRFQPISEHQTREVEQLANHLKEKTDKCSE-LLLSKEQLQRDIQERNEEIE 2148
Query: 405 ETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNL 464
+ + + L +A AD T Q + ++ +E + EL +E+Q ++ + +
Sbjct: 2149 KLE--FRVRELEQALLVSAD-TFQKVEDRKHFGAVEAK-PELSLEVQ-LQAERDAIDRKE 2203
Query: 465 KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
K+ + N+ E+++ M+ + Q ++ +++ ++E KL K
Sbjct: 2204 KEITNLEEQLEQFREELENKNEEVQQLHMQLEIQKKESTTRLQELEQENKLFK 2256
>AF026245-1|AAB86384.1| 1642|Homo sapiens yotiao protein.
Length = 1642
Score = 51.2 bits (117), Expect = 9e-06
Identities = 72/307 (23%), Positives = 139/307 (45%), Gaps = 26/307 (8%)
Query: 173 ITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNL 232
IT NE I + +I L + N+ EKL E+L ++++ +Q +++ L E
Sbjct: 493 ITVNEDQIKLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEELSFS 552
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLV--EEKLSEIKEKDE----NFKQEI 286
+ K ++ +E++K +V E E++ K E N+K ++
Sbjct: 553 REQIQRARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRKELELKHEAEVTNYKIKL 612
Query: 287 DMLNEK--LICDR-REFNETMQEK---NILLS---DLSKKVNKTERE----LEEKQEQL- 332
+ML ++ + DR E E E+ +L S +LSK E E +E+ ++ L
Sbjct: 613 EMLEKEKNAVLDRMAESQEAELERLRTQLLFSHEEELSKLKEDLEIEHRINIEKLKDNLG 672
Query: 333 THLMEQLNDTENNSYKLIENM-FNKVSQIASDFKISNQLS--CELDDESENT-YERISLT 388
H +Q++ +N + IE M F K + I ++ ++S +L N+ E ++L
Sbjct: 673 IHYKQQIDGLQNEMSQKIETMQFEKDNLITKQNQLILEISKLKDLQQSLVNSKSEEMTLQ 732
Query: 389 LDKITNHITYLNTQINE--TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
++++ I L + E T + + +L + + + E+ L+E+ +QLE EN L
Sbjct: 733 INELQKEIEILRQEEKEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSIL 792
Query: 447 LIEIQTV 453
E +T+
Sbjct: 793 KDEKKTL 799
Score = 51.2 bits (117), Expect = 9e-06
Identities = 92/391 (23%), Positives = 176/391 (45%), Gaps = 47/391 (12%)
Query: 93 DLKKLYEDSASELEALKRENIQMHTSDVMV-VPEIIDSLTEVINTLTNGFESLEEVALEI 151
+L KL ED LE R NI+ ++ + + ID L N ++ E+++ +
Sbjct: 648 ELSKLKED----LEIEHRINIEKLKDNLGIHYKQQIDGLQ---NEMSQKIETMQFEKDNL 700
Query: 152 DLKKNSITKDNISIKTLLDKLI-TKNET---DINELRNSIKYLESVKSEYNTANEKLFE- 206
K+N + + +K L L+ +K+E INEL+ I+ L + E T +++ E
Sbjct: 701 ITKQNQLILEISKLKDLQQSLVNSKSEEMTLQINELQKEIEILRQEEKEKGTLEQEVQEL 760
Query: 207 QLNNAV------DKQNCIQEEVDLLKIENQNLL-QXXXXXXXXXXXXXXXXXARDKFIAN 259
QL + +K+N +QE+ L+ EN L + R F+ +
Sbjct: 761 QLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHTPVSQEERLIFLDS 820
Query: 260 LEEMKTMLVEEKLSEIK-EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
++ V EK EI E++E+ KQ+ LNE++ R F + EKN +V
Sbjct: 821 IKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTF--SFAEKNF-------EV 871
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENN---SYKLIENMFNKVSQIASDFKISNQLSCELD 375
N +EL+E+ L + + L D++N YK N+ + + ++ +
Sbjct: 872 N--YQELQEEYACLLKVKDDLEDSKNKQELEYKSKLKALNEELHLQRINPTTVKMKSSVF 929
Query: 376 DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKER 435
DE + T+ +L + ++ T T++ E + + L E ++++DL+EQ LK +
Sbjct: 930 DE-DKTFVAETLEMGEVXEKDT---TELMEKLEVTKREKL-ELSQRLSDLSEQ---LKPK 981
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKD 466
++ N+ E+++++ E V+L ++
Sbjct: 982 PGEISFLNE----EVKSLKPEKEPVSLRCRE 1008
Score = 45.2 bits (102), Expect = 6e-04
Identities = 56/335 (16%), Positives = 145/335 (43%), Gaps = 22/335 (6%)
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
LE + E+ K++ I + N ++ + T+ + E +IK + + ++ ++
Sbjct: 169 LEMMESELAGKQHEIEELNRELEEMRVTYGTEGLQQLQEFEAAIKQRDGIITQLTANLQQ 228
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNL-LQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ + + + + E+ L+I+ Q L A+ + + + ++
Sbjct: 229 ARREKDETMREFLELTEQSQKLQIQFQQLQASETLRNSTHSSTAADLLQAKQQILTHQQQ 288
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC-----DRREFN---ETMQEKNILLSDL 314
++ + L + ++K E+F +I L EK+ D++ N E +QEK ++ +L
Sbjct: 289 LEEQ--DHLLEDYQKKKEDFTMQISFLQEKIKVYEMEQDKKVENSNKEEIQEKETIIEEL 346
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+ K+ + E++ E +++LT + L + + + + + N ++ + + Q S E+
Sbjct: 347 NTKIIEEEKKTLELKDKLTTADKLLGELQEQIVQKNQEIKNMKLELTNSKQKERQSSEEI 406
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII--- 431
+ T E L K + + T I + + + + L + + ++ ++ Q I+
Sbjct: 407 -KQLMGTVEE----LQKRNHKDSQFETDIVQRMEQETQRKLEQLRAELDEMYGQQIVQMK 461
Query: 432 ---LKERLSQLETENKELLIEIQTVRGSNEEVTLN 463
+++ ++Q+E E++ S +T+N
Sbjct: 462 QELIRQHMAQMEEMKTRHKGEMENALRSYSNITVN 496
Score = 36.3 bits (80), Expect = 0.26
Identities = 75/345 (21%), Positives = 146/345 (42%), Gaps = 35/345 (10%)
Query: 127 IDSLTEVINTLTN-GFE-SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR 184
+ SL + + T+T+ G E S+ +V + + +D +S + + +K E I +
Sbjct: 1028 VSSLLDGVVTMTSRGAEGSVSKVNKSFGEESKIMVEDKVSFENMTVGEESKQEQLILDHL 1087
Query: 185 NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
S+ S+++ + N+KL ++LN +QN ++ L++E Q +
Sbjct: 1088 PSVTKESSLRATQPSENDKLQKELNVLKSEQNDLR-----LQMEAQRICLSLVYSTHVDQ 1142
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
+DK + +L+E EEK+ E+ Q+I L E +E +
Sbjct: 1143 VREYMENEKDKALCSLKEELIFAQEEKIKEL--------QKIHQL-ELQTMKTQETGDEG 1193
Query: 305 QEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+ ++L+ L K V+ EE L L L + + K N +K + + D+
Sbjct: 1194 KPLHLLIGKLQKAVS------EECSYFLQTLCSVLGEYYTPALKCEVNAEDK--ENSGDY 1245
Query: 365 KISNQLSCELDD---ESENTYERISLTLDKIT---NHITYLNTQINET--QKNDNAQLLW 416
IS EL D E ++ E + L+K+T N + L T++++ Q+ D +L +
Sbjct: 1246 -ISENEDPELQDYRYEVQDFQENMHTLLNKVTEEYNKLLVLQTRLSKIWGQQTDGMKLEF 1304
Query: 417 EAKKQIADLTEQNIILKE--RLSQLETENKELLIEIQTVRGSNEE 459
+ + TE I + L ++ +K L +Q + + E
Sbjct: 1305 GEENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLE 1349
Score = 33.5 bits (73), Expect = 1.8
Identities = 16/82 (19%), Positives = 45/82 (54%), Gaps = 3/82 (3%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
EE + + + +++ +++ D N K ++ L + ++ + E +QE L+S L +++ +
Sbjct: 1312 EETEFLSIHSQMTNLEDIDVNHKSKLSSLQD---LEKTKLEEQVQELESLISSLXQQLKE 1368
Query: 321 TERELEEKQEQLTHLMEQLNDT 342
TE+ E + L ++ ++++
Sbjct: 1369 TEQNYEAEIHCLQKRLQAVSES 1390
>AB080722-1|BAC81776.1| 833|Homo sapiens hypothetical protein
protein.
Length = 833
Score = 51.2 bits (117), Expect = 9e-06
Identities = 68/324 (20%), Positives = 139/324 (42%), Gaps = 16/324 (4%)
Query: 195 SEYNTANEKL---FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXX 251
S+ N+ E+ + L N + + IQ++V L+ EN NL
Sbjct: 415 SKVNSVTEQCVAKIQYLQNYLKESVQIQKKVMELESENLNLKSKMKPLIFTTQSLIQKVE 474
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+K + NL E K+ ++ KLS+ +E + +E + K + + N+T++EKNI L
Sbjct: 475 TYEKQLKNLVEEKST-IQSKLSKTEEYSKECLKEFKKIISKYNVLQGQ-NKTLEEKNIQL 532
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
S +++ + +L+ K+ + M +N+ N +E M + I + ++ + +
Sbjct: 533 SLEKQQMMEALDQLKSKEHKTQSDMAIVNNENNRMSIEMEAMKTNILLIQDEKEMLEKKT 592
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL--TEQN 429
+L E + + + +I ++ +T++ Q++ K + +L T Q
Sbjct: 593 HQLLKEKSSLGNELKESQLEIIQ--LKEKERLAKTEQETLLQIIETVKDEKLNLETTLQE 650
Query: 430 IILKERLSQLETENKELLIEIQTVRGSNEEVTL-NLKDSSTXXXXXXXXXXXXSNEIEDM 488
++ + E EN IQT + + EE L +K++ + E E +
Sbjct: 651 STAARQIMEREIEN------IQTYQSTAEENFLQEIKNAKSEASIYKNSLSEIGKECEML 704
Query: 489 KTKVMEWKSQFEDLDDVMKQQQKE 512
VME K+ + L + +K+ +E
Sbjct: 705 SKMVMETKTDNQILKEELKKHSQE 728
>X82834-1|CAA58041.1| 2185|Homo sapiens 256 kD golgin protein.
Length = 2185
Score = 50.8 bits (116), Expect = 1e-05
Identities = 91/467 (19%), Positives = 199/467 (42%), Gaps = 49/467 (10%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTE-VINTLT 138
LT KL + + LK +E S LE E ++ + ++ + +I TE ++ T
Sbjct: 1174 LTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKL-SEELAIQLDICCKKTEALLEAKT 1232
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYN 198
N ++ L + S + + + + L+ K T ++EL ++ L ++ N
Sbjct: 1233 NELINISSSKTNAILSRISHCQHRTT--KVKEALLIKTCT-VSELEAQLRQLTEEQNTLN 1289
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
+ ++ QL ++ ++ +++ L E + L + K ++
Sbjct: 1290 ISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELS 1349
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
T++ EE L E K + + +++ LN +L + + ++ EK +S L K+
Sbjct: 1350 ENINAVTLMKEE-LKEKKVEISSLSKQLTDLNVQL-----QNSISLSEKEAAISSLRKQY 1403
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQ----IASDF----KISNQL 370
++ + EL ++ + L+ ++ L+ + ++ + +++ NK S+ S F +L
Sbjct: 1404 DEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKEL 1463
Query: 371 SCELDDESENTYER---ISLT---LDKITNHITYLNTQINETQ---KNDNAQLLWEAKKQ 421
+L+ +S+ YE+ I+L LD+ L ++ + + + + L E K Q
Sbjct: 1464 QIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQ 1523
Query: 422 IADLTEQ--------------NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS 467
A + E N +LK Q + E+KEL+ ++Q + EE +K++
Sbjct: 1524 TARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEA 1583
Query: 468 STXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
N++ MK ++ K + E ++ +K +++ELK
Sbjct: 1584 E-------EKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELK 1623
Score = 49.2 bits (112), Expect = 3e-05
Identities = 91/442 (20%), Positives = 190/442 (42%), Gaps = 31/442 (7%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEII--DSLTEVINTLTNGFESLEEVALE- 150
L+KL+E + E + +Q + ++ S +E + ++ E E +ALE
Sbjct: 481 LQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK-ISQEKEQQESLALEE 539
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN 210
++L+K +I ++ + L + T I EL +S LE E ++ L L
Sbjct: 540 LELQKKAILTESENKLRDLQQEAETYRTRILELESS---LEKSLQENKNQSKDLAVHLEA 596
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE 270
+K N +E+ ++ +++ L+ + ++ +E+++ +E
Sbjct: 597 EKNKHN---KEITVMVEKHKTELESLKHQQDALWTEKLQVL-KQQYQTEMEKLREKCEQE 652
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNET-MQEKNILLSDLSKKVNKTERELEEKQ 329
K + +K+K+ F+ I+ +NEK + ++ + +T ++ + LS++ K +K E EL +
Sbjct: 653 KETLLKDKEIIFQAHIEEMNEKTL-EKLDVKQTELESLSSELSEVLKARHKLEEELSVLK 711
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+Q T M+Q + + + K + +V I + ++S Q + + + N E +
Sbjct: 712 DQ-TDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKER 768
Query: 390 DKITN----HITYLNTQINETQ--------KNDNAQLLWEA-KKQIADLTEQNIILKERL 436
DK H+ L I ++ K D Q A +Q EQ L+++L
Sbjct: 769 DKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKL 828
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED-MKTKVMEW 495
LETE L ++ V ++V L ++E+E +K+ +
Sbjct: 829 LDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVY 888
Query: 496 KSQFEDLDDVMKQQQKELKLGK 517
+S+ ED + ++Q K++ + K
Sbjct: 889 ESKLED-GNKEQEQTKQILVEK 909
Score = 48.4 bits (110), Expect = 6e-05
Identities = 53/214 (24%), Positives = 100/214 (46%), Gaps = 15/214 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+ K +LVE++ + I + E K+EI++L +KL + +E + KK+ K
Sbjct: 900 EQTKQILVEKE-NMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEK 958
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-----KISNQLSCELD 375
+++ +E QE L ++L D E K +EN ++SQ F +++ S +
Sbjct: 959 VKQKAKEMQET---LKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGIS 1015
Query: 376 DESENTYERISLTLDKITN-HITYLNTQIN--ETQKNDNAQLLWEAKK-QIADLTEQNII 431
D ++ +T H LN I+ E + N A+ L E + Q+ + ++
Sbjct: 1016 DAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAE 1075
Query: 432 LKERLSQLETENKELLIEIQTVR--GSNEEVTLN 463
LK+++ E +E+ EI ++ G ++ TLN
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLN 1109
Score = 48.4 bits (110), Expect = 6e-05
Identities = 96/460 (20%), Positives = 178/460 (38%), Gaps = 50/460 (10%)
Query: 100 DSASELEALKRENIQMHTS-DVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
D+ S LE ++E I+ T + ++I + +N + + E+ L+ ++ +
Sbjct: 1016 DAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAE 1075
Query: 159 TKDNISI----KTLLDKLIT-------KNETDINELRNSIKY-------LESVKSEYNTA 200
K I + K ++K IT K +T +NEL+ +K L +++
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 1135
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
EKL LN ++ + +QE++ LK+ L + + + +
Sbjct: 1136 LEKLEVDLNKSLKENTFLQEQLVELKM----LAEEDKRKVSELTSKLKTTDEEFQSLKSS 1191
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEK----LICDRREF-NETMQEKNILLSDLS 315
E +E+K E K+ E ++D+ +K L E N + + N +LS +S
Sbjct: 1192 HEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRIS 1251
Query: 316 KKVNKTER-------------ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
++T + ELE + QLT LN + + +E N++ + +
Sbjct: 1252 HCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKA 1311
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
D + L E N + S IT L+ IN L E K +I
Sbjct: 1312 DIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEE--LKEKKVEI 1369
Query: 423 ADLTEQNIILKERL-SQLETENKELLIEIQTVRGSNEEVTL--NLKDSSTXXXXXXXXXX 479
+ L++Q L +L + + KE I + E+ L ++D S
Sbjct: 1370 SSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKI 1429
Query: 480 XXSNEIEDMKTKVMEWK----SQFEDLDDVMKQQQKELKL 515
+++D K EWK S+F + +K+ Q +L+L
Sbjct: 1430 SALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLEL 1469
Score = 45.6 bits (103), Expect = 4e-04
Identities = 75/373 (20%), Positives = 160/373 (42%), Gaps = 32/373 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEI-IDSLTEVINTLT 138
L+E + +LK+ + +S + L N+Q+ S + E I SL + +
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDE-- 1405
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITK-------NETDINELRNSIKYLE 191
E L++V ++ K ++++K+ IS +D K ++ + +N++K L+
Sbjct: 1406 EKCELLDQVQ-DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQ 1464
Query: 192 ---SVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXX 248
+KS+ ++ L +D+QN + D LK E ++
Sbjct: 1465 IQLELKSKEAYEKDEQINLLKEELDQQN---KRFDCLKGEMEDDKSKMEKKESNLETELK 1521
Query: 249 XXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
AR I LE+ T E + + E +N+ Q+ D+ +++L+ + F E +EK+
Sbjct: 1522 SQTAR---IMELEDHITQKTIE-IESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKD 1577
Query: 309 ILLSDLSKKVNKTER-------ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK-VSQI 360
+ + +K+ E ELE K+++L H+ + E L + + ++ +++
Sbjct: 1578 NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1637
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDKIT-NHITYLNTQINETQKNDNAQLLWEAK 419
A + + Q + + + E K T +H++ LNT++ E ++ +L E
Sbjct: 1638 AELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERER--EVHILEEKL 1695
Query: 420 KQIADLTEQNIIL 432
K + + +I+
Sbjct: 1696 KSVESSQSETLIV 1708
Score = 44.4 bits (100), Expect = 0.001
Identities = 63/353 (17%), Positives = 137/353 (38%), Gaps = 17/353 (4%)
Query: 175 KNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEEVDLLKIENQNLL 233
+ E + + S+ + V+ E N + + L N D Q +QE+ +I Q +
Sbjct: 1798 QEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIK 1857
Query: 234 QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL 293
+ L+ ++ M K +E+ E++ K + ++ KL
Sbjct: 1858 ELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKL 1917
Query: 294 ICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM-EQLNDTENNSYKLIEN 352
+ + + ++ K L+ ++ K +E+ Q+ L L E + E + +
Sbjct: 1918 LSNMEAQHNDLEFK---LAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQE 1974
Query: 353 MFNKVSQIASDFKISN-----QLSCELDDESENTYERISLTLDKITNHITYLNTQINETQ 407
K+ Q D ++ + QL E + + + + +T+ + N + ++ E+
Sbjct: 1975 REEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESH 2034
Query: 408 KNDNAQLLWEAKKQIADL----TEQNIILKERLSQLETENKEL---LIEIQTVRGSNEEV 460
+ + QLL + ++ DL IL R ++ + ++L L E+Q E
Sbjct: 2035 QEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ 2094
Query: 461 TLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
N + + + I D K K E++ Q +L+D +K+ +K +
Sbjct: 2095 EENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNV 2147
Score = 41.9 bits (94), Expect = 0.005
Identities = 95/453 (20%), Positives = 180/453 (39%), Gaps = 46/453 (10%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRE-NIQMHTSDVMVVPEIIDSLTEVINTLT 138
L +KL E K LKK E++A EL +++ N +M I D+++ +
Sbjct: 970 LKKKLLDQEAK---LKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK 1026
Query: 139 NGFESLEEVALE-----IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESV 193
ESL EV I + + + + ++ + + + + E ++ EL+ I
Sbjct: 1027 EQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCE 1086
Query: 194 KSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXAR 253
K E N L K+ ++++ L +++ Q L Q
Sbjct: 1087 KEEMNKEITWL---------KEEGVKQDTTLNELQEQ-LKQKSAHVNSLAQDETKLKAHL 1136
Query: 254 DKFIANLEEM--KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF---NETMQEKN 308
+K +L + + ++E+L E+K E K+++ L KL EF + ++ N
Sbjct: 1137 EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSN 1196
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN 368
L D S + K EL + + E L + + N +LI +K + I S +IS+
Sbjct: 1197 KSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTN--ELINISSSKTNAILS--RISH 1252
Query: 369 QLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL--WEAKKQIADLT 426
C + T + +L + T ++ L Q+ + + N + +A Q+ +
Sbjct: 1253 ---C----QHRTTKVKEALLIKTCT--VSELEAQLRQLTEEQNTLNISFQQATHQLEEKE 1303
Query: 427 EQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEI- 485
Q +K + L TE + L E G N++ + K+S + +
Sbjct: 1304 NQIKSMKADIESLVTEKEALQKE-----GGNQQQAASEKESCITQLKKELSENINAVTLM 1358
Query: 486 -EDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
E++K K +E S + L D+ Q Q + L +
Sbjct: 1359 KEELKEKKVEISSLSKQLTDLNVQLQNSISLSE 1391
Score = 35.1 bits (77), Expect = 0.60
Identities = 51/268 (19%), Positives = 104/268 (38%), Gaps = 20/268 (7%)
Query: 142 ESLEEVALEIDLKKNSIT--KDNISIKTL--LDKLITKNETDINELRNSI-KYLESVKSE 196
+ LE V L + K+ + +D + ++ L +L K E I ++ + +E + +
Sbjct: 1606 KELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1665
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
Y E +LN + ++ + EV +L+ + +++ ++
Sbjct: 1666 YKKGTESHLSELNTKLQER---EREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQE 1722
Query: 257 IANLEEMKTMLVEEKLSEIKE---KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
A+ + EEK+S ++ + E Q + E+ + E QE+ I
Sbjct: 1723 EADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLI---- 1778
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
K+ E + E Q + HL E+L + +N Y LI + ++ + L
Sbjct: 1779 ---KLEHAEAKQHEDQSMIGHLQEELEE-KNKKYSLIVAQHVEKEGGKNNIQAKQNLENV 1834
Query: 374 LDDESENTYERISLTLDKITNHITYLNT 401
DD + E+ LT + I L++
Sbjct: 1835 FDDVQKTLQEK-ELTCQILEQKIKELDS 1861
Score = 35.1 bits (77), Expect = 0.60
Identities = 38/186 (20%), Positives = 82/186 (44%), Gaps = 8/186 (4%)
Query: 175 KNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQ-NCIQE-EVDLLKIENQNL 232
K E + EL+++ L+ + E+NT + ++L + + N QE E +LL+ +
Sbjct: 1980 KQEQEDLELKHN-STLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEET 2038
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEK 292
Q ++ + EE T V + ++++E + ++Q+++ E
Sbjct: 2039 NQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ-EEN 2097
Query: 293 LICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIEN 352
D N T+ E L+ + ++ ++ + +E +EQ+ +L ++L E N Y
Sbjct: 2098 PGND----NVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVYATTVG 2153
Query: 353 MFNKVS 358
KV+
Sbjct: 2154 HLTKVA 2159
Score = 33.9 bits (74), Expect = 1.4
Identities = 51/270 (18%), Positives = 116/270 (42%), Gaps = 26/270 (9%)
Query: 268 VEEKLSEI-KEKDENFKQEIDMLNEKLICDRREFNETM-QEKNILLSDLSKKVNKT---- 321
++E+L E+ K KD + ++ ++ + + D + E + Q+K +++++ +++++T
Sbjct: 323 LDERLQELEKIKDLHMAEKTKLITQ--LRDAKNLIEQLEQDKGMVIAETKRQMHETLEMK 380
Query: 322 ERE---LEEKQEQLTHLMEQLNDTENNSYK-LIENMFNKVSQIASDFKISNQLSCELDD- 376
E E L + +Q+T E+L + + S + E + +S + +L E+D+
Sbjct: 381 EEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 440
Query: 377 ----ESENTYERISL--TLDKITNHITYL-----NTQINETQKNDNAQLLWEAKKQIADL 425
E + ERISL L ++ + + QI + QK +L + ++ L
Sbjct: 441 IKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKL 500
Query: 426 TEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD--SSTXXXXXXXXXXXXSN 483
+ +E++ +++ ++I + E + L +
Sbjct: 501 QTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQ 560
Query: 484 EIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
E E +T+++E +S E K Q K+L
Sbjct: 561 EAETYRTRILELESSLEKSLQENKNQSKDL 590
Score = 33.1 bits (72), Expect = 2.4
Identities = 48/225 (21%), Positives = 96/225 (42%), Gaps = 14/225 (6%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK----NILLS 312
I LE+ K M++ E ++ E E ++EI L ++ + E ++K
Sbjct: 355 IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE 414
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK---LIENMFNKVSQIASDF--KIS 367
+L K ++ ++ E +++ + EQ+ E S + ++ ++V Q D K S
Sbjct: 415 ELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 474
Query: 368 NQLSCELD--DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQL-LWEAKKQIAD 424
+ +L E E + LT T + +K+ + L + + K+Q
Sbjct: 475 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQES 534
Query: 425 LTEQNIILKERLSQLETENK--ELLIEIQTVRGSNEEVTLNLKDS 467
L + + L+++ E+ENK +L E +T R E+ +L+ S
Sbjct: 535 LALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 579
>X52889-1|CAA37068.1| 1934|Homo sapiens cardiac beta myosin heavy
chain protein.
Length = 1934
Score = 50.8 bits (116), Expect = 1e-05
Identities = 95/492 (19%), Positives = 197/492 (40%), Gaps = 44/492 (8%)
Query: 41 QQNVGVGDKTVAEL-KND-EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLY 98
Q N+ ++ +L KN ++ + ++++ LT K E + ++LK+
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRNVEDECSELKRDI 954
Query: 99 EDSASELEALKREN------IQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+D L +++E ++ T ++ + EII LT+ L + +L+++ E
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
D K N++TK + K E +++L S++ + V+ + A KL L
Sbjct: 1015 D-KVNTLTKAKV-----------KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-- 1060
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +++ + E D +++ + L + + L+E++ + E+
Sbjct: 1061 LTQESIMDLENDKQQLD-ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARI--EE 1117
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS---DLSKK----VNKTERE 324
L E E + + +++ L L + E +E ++E S +++KK K R+
Sbjct: 1118 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRD 1177
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYE 383
LEE Q L +S + + + ++ K ++ ELDD + N E
Sbjct: 1178 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-ME 1236
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL--ET 441
+I + L Q+NE + E ++ + DLT Q L+ +L +
Sbjct: 1237 QIIKAKANLEKMCRTLEDQMNEHRSKAE-----ETQRSVNDLTSQRAKLQTENGELSRQL 1291
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ KE LI Q RG T L+D ++ ++ + + Q+E+
Sbjct: 1292 DEKEALIS-QLTRG-KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349
Query: 502 LDDVMKQQQKEL 513
+ + Q+ L
Sbjct: 1350 ETEAKAELQRVL 1361
Score = 41.9 bits (94), Expect = 0.005
Identities = 83/465 (17%), Positives = 178/465 (38%), Gaps = 43/465 (9%)
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLT-EVINTLTNGFE 142
LT A+ K L++ +D LE K+ + + + + ++ LT E I L N +
Sbjct: 1020 LTKAKVK---LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL--KLTQESIMDLENDKQ 1074
Query: 143 SLEEVALEIDLKKNSIT---KDNISIKTLLDKLITKNETDINELRNSIKY-------LES 192
L+E + D + N++ +D ++ + L K + + + I EL ++ +E
Sbjct: 1075 QLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEK 1134
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQE-----EVDLLKIEN---QNLLQXXXXXXXXXX 244
++S+ + E++ E+L A +C E E + K+ + LQ
Sbjct: 1135 LRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRK 1194
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLS---EIKEKDENFKQEIDM-LNEKLIC----- 295
+ I NL+ +K L +EK E+ + N +Q I N + +C
Sbjct: 1195 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
E +E ++DL+ + K + E E QL ++ + + +
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 356 KVSQIASDFKISNQLSCELD------DESENTYERISLTLDKITNHITYLNTQINETQKN 409
Q+ + K N L+ L D YE + ++ ++ N+++ + +
Sbjct: 1315 LKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1374
Query: 410 DNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSST 469
+A ++ +L E L +RL + E + + + ++ + + ++D
Sbjct: 1375 YET----DAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMV 1430
Query: 470 XXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ + + EWK ++E+ ++ QKE +
Sbjct: 1431 DVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1475
Score = 41.9 bits (94), Expect = 0.005
Identities = 61/310 (19%), Positives = 122/310 (39%), Gaps = 22/310 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLD-KLITKNETDINELRNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK ++ KL K+E RN ++ ++S+++ +
Sbjct: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFI-A 258
E L + + E L N+ + D + A
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
N + + + + E+ + ++ + E + ++ RE ET + +L S + +
Sbjct: 1664 NDDLKENIAIVERRNNLQAELEELRAVVEQTERSRKLADRELIETSERVQLLHSQNTSLI 1723
Query: 319 N---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
N K + +L + Q ++ +++ + E + K I + + +A + K S L+
Sbjct: 1724 NQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD----AAMMAEELKKEQDTSAHLE 1779
Query: 376 DESENTYERI 385
+N + I
Sbjct: 1780 RMKKNMEQTI 1789
Score = 37.9 bits (84), Expect = 0.085
Identities = 92/408 (22%), Positives = 164/408 (40%), Gaps = 42/408 (10%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q ++ V + + L+ + + + I L L +K
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF-E 142
+ + K+ YE+S SELE+ ++E SL+ + L N + E
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKE---------------ARSLSTELFKLKNAYEE 1490
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
SLE LE ++N ++ IS L ++L + +T I+EL K LE+ K E +A E
Sbjct: 1491 SLEH--LETFKRENKNLQEEIS--DLTEQLGSSGKT-IHELEKVRKQLEAEKMELQSALE 1545
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ L + K Q E + +K E + L A+ + ++
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKL---------AEKDEEMEQAKRNHLRVVDS 1596
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
++T L E S + K E D LNE I N E + L + T+
Sbjct: 1597 LQTSLDAETRSRNEALRVKKKMEGD-LNEMEI-QLSHANRMAAEAQKQVKSLQSLLKDTQ 1654
Query: 323 RELEEKQEQLTHLMEQLNDTE--NNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
+L++ L E + E NN +E + V Q K++++ E + +
Sbjct: 1655 IQLDDAVRANDDLKENIAIVERRNNLQAELEELRAVVEQTERSRKLADRELIETSERVQL 1714
Query: 381 TYERISLTLD---KITNHITYLNTQINE-TQKNDNAQLLWEAKKQIAD 424
+ + + ++ K+ ++ L T++ E Q+ NA+ +AKK I D
Sbjct: 1715 LHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE--EKAKKAITD 1760
Score = 34.7 bits (76), Expect = 0.80
Identities = 37/222 (16%), Positives = 98/222 (44%), Gaps = 6/222 (2%)
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+R + +M+E+ L + +K +ELEEK + L+++ ND + +N+ +
Sbjct: 844 EREKEMASMKEEFTALKEALEKSEARRKELEEK---MVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQL 414
+ K QL ++ + +E + + + +T + + +E +++ D+ +L
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRNVEDECSELKRDIDDLEL 959
Query: 415 LWEAKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1061
>U41740-1|AAC50434.1| 2230|Homo sapiens trans-Golgi p230 protein.
Length = 2230
Score = 50.8 bits (116), Expect = 1e-05
Identities = 91/467 (19%), Positives = 199/467 (42%), Gaps = 49/467 (10%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTE-VINTLT 138
LT KL + + LK +E S LE E ++ + ++ + +I TE ++ T
Sbjct: 1174 LTSKLKTTDEEFQSLKSSHEKSNKSLEDKSLEFKKL-SEELAIQLDICCKKTEALLEAKT 1232
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYN 198
N ++ L + S + + + + L+ K T ++EL ++ L ++ N
Sbjct: 1233 NELINISSSKTNAILSRISHCQHRTT--KVKEALLIKTCT-VSELEAQLRQLTEEQNTLN 1289
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
+ ++ QL ++ ++ +++ L E + L + K ++
Sbjct: 1290 ISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELS 1349
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
T++ EE L E K + + +++ LN +L + + ++ EK +S L K+
Sbjct: 1350 ENINAVTLMKEE-LKEKKVEISSLSKQLTDLNVQL-----QNSISLSEKEAAISSLRKQY 1403
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQ----IASDF----KISNQL 370
++ + EL ++ + L+ ++ L+ + ++ + +++ NK S+ S F +L
Sbjct: 1404 DEEKCELLDQVQDLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKEL 1463
Query: 371 SCELDDESENTYER---ISLT---LDKITNHITYLNTQINETQ---KNDNAQLLWEAKKQ 421
+L+ +S+ YE+ I+L LD+ L ++ + + + + L E K Q
Sbjct: 1464 QIQLELKSKEAYEKDEQINLLKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQ 1523
Query: 422 IADLTEQ--------------NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS 467
A + E N +LK Q + E+KEL+ ++Q + EE +K++
Sbjct: 1524 TARIMELEDHITQKTIEIESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEA 1583
Query: 468 STXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
N++ MK ++ K + E ++ +K +++ELK
Sbjct: 1584 E-------EKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELK 1623
Score = 49.2 bits (112), Expect = 3e-05
Identities = 91/442 (20%), Positives = 190/442 (42%), Gaps = 31/442 (7%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEII--DSLTEVINTLTNGFESLEEVALE- 150
L+KL+E + E + +Q + ++ S +E + ++ E E +ALE
Sbjct: 481 LQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK-ISQEKEQQESLALEE 539
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN 210
++L+K +I ++ + L + T I EL +S LE E ++ L L
Sbjct: 540 LELQKKAILTESENKLRDLQQEAETYRTRILELESS---LEKSLQENKNQSKDLAVHLEA 596
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE 270
+K N +E+ ++ +++ L+ + ++ +E+++ +E
Sbjct: 597 EKNKHN---KEITVMVEKHKTELESLKHQQDALWTEKLQVL-KQQYQTEMEKLREKCEQE 652
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNET-MQEKNILLSDLSKKVNKTERELEEKQ 329
K + +K+K+ F+ I+ +NEK + ++ + +T ++ + LS++ K +K E EL +
Sbjct: 653 KETLLKDKEIIFQAHIEEMNEKTL-EKLDVKQTELESLSSELSEVLKARHKLEEELSVLK 711
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+Q T M+Q + + + K + +V I + ++S Q + + + N E +
Sbjct: 712 DQ-TDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKER 768
Query: 390 DKITN----HITYLNTQINETQ--------KNDNAQLLWEA-KKQIADLTEQNIILKERL 436
DK H+ L I ++ K D Q A +Q EQ L+++L
Sbjct: 769 DKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKL 828
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED-MKTKVMEW 495
LETE L ++ V ++V L ++E+E +K+ +
Sbjct: 829 LDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVY 888
Query: 496 KSQFEDLDDVMKQQQKELKLGK 517
+S+ ED + ++Q K++ + K
Sbjct: 889 ESKLED-GNKEQEQTKQILVEK 909
Score = 48.4 bits (110), Expect = 6e-05
Identities = 53/214 (24%), Positives = 100/214 (46%), Gaps = 15/214 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+ K +LVE++ + I + E K+EI++L +KL + +E + KK+ K
Sbjct: 900 EQTKQILVEKE-NMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEK 958
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-----KISNQLSCELD 375
+++ +E QE L ++L D E K +EN ++SQ F +++ S +
Sbjct: 959 VKQKAKEMQET---LKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGIS 1015
Query: 376 DESENTYERISLTLDKITN-HITYLNTQIN--ETQKNDNAQLLWEAKK-QIADLTEQNII 431
D ++ +T H LN I+ E + N A+ L E + Q+ + ++
Sbjct: 1016 DAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAE 1075
Query: 432 LKERLSQLETENKELLIEIQTVR--GSNEEVTLN 463
LK+++ E +E+ EI ++ G ++ TLN
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLN 1109
Score = 48.4 bits (110), Expect = 6e-05
Identities = 96/460 (20%), Positives = 178/460 (38%), Gaps = 50/460 (10%)
Query: 100 DSASELEALKRENIQMHTS-DVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
D+ S LE ++E I+ T + ++I + +N + + E+ L+ ++ +
Sbjct: 1016 DAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAE 1075
Query: 159 TKDNISI----KTLLDKLIT-------KNETDINELRNSIKY-------LESVKSEYNTA 200
K I + K ++K IT K +T +NEL+ +K L +++
Sbjct: 1076 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQKSAHVNSLAQDETKLKAH 1135
Query: 201 NEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
EKL LN ++ + +QE++ LK+ L + + + +
Sbjct: 1136 LEKLEVDLNKSLKENTFLQEQLVELKM----LAEEDKRKVSELTSKLKTTDEEFQSLKSS 1191
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEK----LICDRREF-NETMQEKNILLSDLS 315
E +E+K E K+ E ++D+ +K L E N + + N +LS +S
Sbjct: 1192 HEKSNKSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTNELINISSSKTNAILSRIS 1251
Query: 316 KKVNKTER-------------ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
++T + ELE + QLT LN + + +E N++ + +
Sbjct: 1252 HCQHRTTKVKEALLIKTCTVSELEAQLRQLTEEQNTLNISFQQATHQLEEKENQIKSMKA 1311
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
D + L E N + S IT L+ IN L E K +I
Sbjct: 1312 DIESLVTEKEALQKEGGNQQQAASEKESCITQLKKELSENINAVTLMKEE--LKEKKVEI 1369
Query: 423 ADLTEQNIILKERL-SQLETENKELLIEIQTVRGSNEEVTL--NLKDSSTXXXXXXXXXX 479
+ L++Q L +L + + KE I + E+ L ++D S
Sbjct: 1370 SSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLSFKVDTLSKEKI 1429
Query: 480 XXSNEIEDMKTKVMEWK----SQFEDLDDVMKQQQKELKL 515
+++D K EWK S+F + +K+ Q +L+L
Sbjct: 1430 SALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQIQLEL 1469
Score = 45.6 bits (103), Expect = 4e-04
Identities = 75/373 (20%), Positives = 160/373 (42%), Gaps = 32/373 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEI-IDSLTEVINTLT 138
L+E + +LK+ + +S + L N+Q+ S + E I SL + +
Sbjct: 1348 LSENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQNSISLSEKEAAISSLRKQYDE-- 1405
Query: 139 NGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITK-------NETDINELRNSIKYLE 191
E L++V ++ K ++++K+ IS +D K ++ + +N++K L+
Sbjct: 1406 EKCELLDQVQ-DLSFKVDTLSKEKISALEQVDDWSNKFSEWKKKAQSRFTQHQNTVKELQ 1464
Query: 192 ---SVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXX 248
+KS+ ++ L +D+QN + D LK E ++
Sbjct: 1465 IQLELKSKEAYEKDEQINLLKEELDQQN---KRFDCLKGEMEDDKSKMEKKESNLETELK 1521
Query: 249 XXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
AR I LE+ T E + + E +N+ Q+ D+ +++L+ + F E +EK+
Sbjct: 1522 SQTAR---IMELEDHITQKTIE-IESLNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKD 1577
Query: 309 ILLSDLSKKVNKTER-------ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNK-VSQI 360
+ + +K+ E ELE K+++L H+ + E L + + ++ +++
Sbjct: 1578 NRVKEAEEKILTLENQVYSMKAELETKKKELEHVNLSVKSKEEELKALEDRLESESAAKL 1637
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDKIT-NHITYLNTQINETQKNDNAQLLWEAK 419
A + + Q + + + E K T +H++ LNT++ E ++ +L E
Sbjct: 1638 AELKRKAEQKIAAIKKQLLSQMEEKEEQYKKGTESHLSELNTKLQERER--EVHILEEKL 1695
Query: 420 KQIADLTEQNIIL 432
K + + +I+
Sbjct: 1696 KSVESSQSETLIV 1708
Score = 44.4 bits (100), Expect = 0.001
Identities = 63/353 (17%), Positives = 137/353 (38%), Gaps = 17/353 (4%)
Query: 175 KNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEEVDLLKIENQNLL 233
+ E + + S+ + V+ E N + + L N D Q +QE+ +I Q +
Sbjct: 1798 QEELEEKNKKYSLIVAQHVEKEGGKNNIQAKQNLENVFDDVQKTLQEKELTCQILEQKIK 1857
Query: 234 QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL 293
+ L+ ++ M K +E+ E++ K + ++ KL
Sbjct: 1858 ELDSCLVRQKEVHRVEMEELTSKYEKLQALQQMDGRNKPTELLEENTEEKSKSHLVQPKL 1917
Query: 294 ICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM-EQLNDTENNSYKLIEN 352
+ + + ++ K L+ ++ K +E+ Q+ L L E + E + +
Sbjct: 1918 LSNMEAQHNDLEFK---LAGAEREKQKLGKEIVRLQKDLRMLRKEHQQELEILKKEYDQE 1974
Query: 353 MFNKVSQIASDFKISN-----QLSCELDDESENTYERISLTLDKITNHITYLNTQINETQ 407
K+ Q D ++ + QL E + + + + +T+ + N + ++ E+
Sbjct: 1975 REEKIKQEQEDLELKHNSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESH 2034
Query: 408 KNDNAQLLWEAKKQIADL----TEQNIILKERLSQLETENKEL---LIEIQTVRGSNEEV 460
+ + QLL + ++ DL IL R ++ + ++L L E+Q E
Sbjct: 2035 QEETNQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ 2094
Query: 461 TLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
N + + + I D K K E++ Q +L+D +K+ +K +
Sbjct: 2095 EENPGNDNVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNV 2147
Score = 41.9 bits (94), Expect = 0.005
Identities = 95/453 (20%), Positives = 180/453 (39%), Gaps = 46/453 (10%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRE-NIQMHTSDVMVVPEIIDSLTEVINTLT 138
L +KL E K LKK E++A EL +++ N +M I D+++ +
Sbjct: 970 LKKKLLDQEAK---LKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK 1026
Query: 139 NGFESLEEVALE-----IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESV 193
ESL EV I + + + + ++ + + + + E ++ EL+ I
Sbjct: 1027 EQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCE 1086
Query: 194 KSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXAR 253
K E N L K+ ++++ L +++ Q L Q
Sbjct: 1087 KEEMNKEITWL---------KEEGVKQDTTLNELQEQ-LKQKSAHVNSLAQDETKLKAHL 1136
Query: 254 DKFIANLEEM--KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF---NETMQEKN 308
+K +L + + ++E+L E+K E K+++ L KL EF + ++ N
Sbjct: 1137 EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSN 1196
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN 368
L D S + K EL + + E L + + N +LI +K + I S +IS+
Sbjct: 1197 KSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTN--ELINISSSKTNAILS--RISH 1252
Query: 369 QLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL--WEAKKQIADLT 426
C + T + +L + T ++ L Q+ + + N + +A Q+ +
Sbjct: 1253 ---C----QHRTTKVKEALLIKTCT--VSELEAQLRQLTEEQNTLNISFQQATHQLEEKE 1303
Query: 427 EQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEI- 485
Q +K + L TE + L E G N++ + K+S + +
Sbjct: 1304 NQIKSMKADIESLVTEKEALQKE-----GGNQQQAASEKESCITQLKKELSENINAVTLM 1358
Query: 486 -EDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
E++K K +E S + L D+ Q Q + L +
Sbjct: 1359 KEELKEKKVEISSLSKQLTDLNVQLQNSISLSE 1391
Score = 35.1 bits (77), Expect = 0.60
Identities = 51/268 (19%), Positives = 104/268 (38%), Gaps = 20/268 (7%)
Query: 142 ESLEEVALEIDLKKNSIT--KDNISIKTL--LDKLITKNETDINELRNSI-KYLESVKSE 196
+ LE V L + K+ + +D + ++ L +L K E I ++ + +E + +
Sbjct: 1606 KELEHVNLSVKSKEEELKALEDRLESESAAKLAELKRKAEQKIAAIKKQLLSQMEEKEEQ 1665
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
Y E +LN + ++ + EV +L+ + +++ ++
Sbjct: 1666 YKKGTESHLSELNTKLQER---EREVHILEEKLKSVESSQSETLIVPRSAKNVAAYTEQE 1722
Query: 257 IANLEEMKTMLVEEKLSEIKE---KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSD 313
A+ + EEK+S ++ + E Q + E+ + E QE+ I
Sbjct: 1723 EADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVSSHFEMRCQYQERLI---- 1778
Query: 314 LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCE 373
K+ E + E Q + HL E+L + +N Y LI + ++ + L
Sbjct: 1779 ---KLEHAEAKQHEDQSMIGHLQEELEE-KNKKYSLIVAQHVEKEGGKNNIQAKQNLENV 1834
Query: 374 LDDESENTYERISLTLDKITNHITYLNT 401
DD + E+ LT + I L++
Sbjct: 1835 FDDVQKTLQEK-ELTCQILEQKIKELDS 1861
Score = 33.9 bits (74), Expect = 1.4
Identities = 51/270 (18%), Positives = 116/270 (42%), Gaps = 26/270 (9%)
Query: 268 VEEKLSEI-KEKDENFKQEIDMLNEKLICDRREFNETM-QEKNILLSDLSKKVNKT---- 321
++E+L E+ K KD + ++ ++ + + D + E + Q+K +++++ +++++T
Sbjct: 323 LDERLQELEKIKDLHMAEKTKLITQ--LRDAKNLIEQLEQDKGMVIAETKRQMHETLEMK 380
Query: 322 ERE---LEEKQEQLTHLMEQLNDTENNSYK-LIENMFNKVSQIASDFKISNQLSCELDD- 376
E E L + +Q+T E+L + + S + E + +S + +L E+D+
Sbjct: 381 EEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 440
Query: 377 ----ESENTYERISL--TLDKITNHITYL-----NTQINETQKNDNAQLLWEAKKQIADL 425
E + ERISL L ++ + + QI + QK +L + ++ L
Sbjct: 441 IKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKL 500
Query: 426 TEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD--SSTXXXXXXXXXXXXSN 483
+ +E++ +++ ++I + E + L +
Sbjct: 501 QTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQ 560
Query: 484 EIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
E E +T+++E +S E K Q K+L
Sbjct: 561 EAETYRTRILELESSLEKSLQENKNQSKDL 590
Score = 33.9 bits (74), Expect = 1.4
Identities = 36/175 (20%), Positives = 79/175 (45%), Gaps = 8/175 (4%)
Query: 175 KNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQ-NCIQE-EVDLLKIENQNL 232
K E + EL+++ L+ + E+NT + ++L + + N QE E +LL+ +
Sbjct: 1980 KQEQEDLELKHN-STLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAELLESHQEET 2038
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEK 292
Q ++ + EE T V + ++++E + ++Q+++ E
Sbjct: 2039 NQLLKKIAEKDDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQ-EEN 2097
Query: 293 LICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSY 347
D N T+ E L+ + ++ ++ + +E +EQ+ +L ++L E N Y
Sbjct: 2098 PGND----NVTIMELQTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKKYEKNVY 2148
Score = 33.1 bits (72), Expect = 2.4
Identities = 48/225 (21%), Positives = 96/225 (42%), Gaps = 14/225 (6%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK----NILLS 312
I LE+ K M++ E ++ E E ++EI L ++ + E ++K
Sbjct: 355 IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE 414
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK---LIENMFNKVSQIASDF--KIS 367
+L K ++ ++ E +++ + EQ+ E S + ++ ++V Q D K S
Sbjct: 415 ELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 474
Query: 368 NQLSCELD--DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQL-LWEAKKQIAD 424
+ +L E E + LT T + +K+ + L + + K+Q
Sbjct: 475 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQES 534
Query: 425 LTEQNIILKERLSQLETENK--ELLIEIQTVRGSNEEVTLNLKDS 467
L + + L+++ E+ENK +L E +T R E+ +L+ S
Sbjct: 535 LALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 579
>M58018-1|AAA62830.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 50.8 bits (116), Expect = 1e-05
Identities = 95/492 (19%), Positives = 197/492 (40%), Gaps = 44/492 (8%)
Query: 41 QQNVGVGDKTVAEL-KND-EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLY 98
Q N+ ++ +L KN ++ + ++++ LT K E + ++LK+
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 99 EDSASELEALKREN------IQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+D L +++E ++ T ++ + EII LT+ L + +L+++ E
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
D K N++TK + K E +++L S++ + V+ + A KL L
Sbjct: 1015 D-KVNTLTKAKV-----------KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-- 1060
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +++ + E D +++ + L + + L+E++ + E+
Sbjct: 1061 LTQESIMDLENDKQQLD-ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARI--EE 1117
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS---DLSKK----VNKTERE 324
L E E + + +++ L L + E +E ++E S +++KK K R+
Sbjct: 1118 LEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 1177
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYE 383
LEE Q L +S + + + ++ K ++ ELDD + N E
Sbjct: 1178 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-ME 1236
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL--ET 441
+I + L Q+NE + E ++ + DLT Q L+ +L +
Sbjct: 1237 QIIKAKANLEKMCRTLEDQMNEHRSKAE-----ETQRSVNDLTSQRAKLQTENGELSRQL 1291
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ KE LI Q RG T L+D ++ ++ + + Q+E+
Sbjct: 1292 DEKEALIS-QLTRG-KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349
Query: 502 LDDVMKQQQKEL 513
+ + Q+ L
Sbjct: 1350 ETEAKAELQRVL 1361
Score = 40.7 bits (91), Expect = 0.012
Identities = 50/260 (19%), Positives = 108/260 (41%), Gaps = 30/260 (11%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDL 314
ANLE+M L E++++E + K E ++ ++ L KL + E + + EK L+S L
Sbjct: 1243 ANLEKMCRTL-EDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL 1301
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++ ++LE+ + QL E+ +N +++ + + ++ + EL
Sbjct: 1302 TRGKLTYTQQLEDLKRQL----EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 1357
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+R+ L K + + T+ ET + L EAKK++A +
Sbjct: 1358 --------QRV---LSKANSEVAQWRTKY-ETDAIQRTEELEEAKKKLA----------Q 1395
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
RL + E + + + ++ + + ++D + + + E
Sbjct: 1396 RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1455
Query: 495 WKSQFEDLDDVMKQQQKELK 514
WK ++E+ ++ QKE +
Sbjct: 1456 WKQKYEESQSELESSQKEAR 1475
Score = 39.9 bits (89), Expect = 0.021
Identities = 60/311 (19%), Positives = 122/311 (39%), Gaps = 23/311 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLD-KLITKNETDINELRNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK ++ KL K+E RN ++ ++S+++ +
Sbjct: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E L + + E L N+ + D +
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 260 LEEMK--TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K +VE + + ++ + E + ++ +E ET + +L S +
Sbjct: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723
Query: 318 VN---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+N K + +L + Q ++ +++ + E + K I + + +A + K S L
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD----AAMMAEELKKEQDTSAHL 1779
Query: 375 DDESENTYERI 385
+ +N + I
Sbjct: 1780 ERMKKNMEQTI 1790
Score = 36.7 bits (81), Expect = 0.20
Identities = 92/409 (22%), Positives = 163/409 (39%), Gaps = 43/409 (10%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q ++ V + + L+ + + + I L L +K
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF-E 142
+ + K+ YE+S SELE+ ++E SL+ + L N + E
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKE---------------ARSLSTELFKLKNAYEE 1490
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
SLE LE ++N ++ IS L ++L + +T I+EL K LE+ K E +A E
Sbjct: 1491 SLEH--LETFKRENKNLQEEIS--DLTEQLGSSGKT-IHELEKVRKQLEAEKMELQSALE 1545
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ L + K Q E + +K E + L A+ + ++
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKL---------AEKDEEMEQAKRNHLRVVDS 1596
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
++T L E S + K E D LNE I N E + L + T+
Sbjct: 1597 LQTSLDAETRSRNEALRVKKKMEGD-LNEMEI-QLSHANRMAAEAQKQVKSLQSLLKDTQ 1654
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKL---IENMFNKVSQIASDFKISNQLSCELDDESE 379
+L++ L E + E + L +E + V Q K++ Q E + +
Sbjct: 1655 IQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ 1714
Query: 380 NTYERISLTLD---KITNHITYLNTQINE-TQKNDNAQLLWEAKKQIAD 424
+ + + ++ K+ ++ L T++ E Q+ NA+ +AKK I D
Sbjct: 1715 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE--EKAKKAITD 1761
Score = 35.5 bits (78), Expect = 0.46
Identities = 38/222 (17%), Positives = 98/222 (44%), Gaps = 6/222 (2%)
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+R + +M+E+ L + +K +ELEEK + L+++ ND + +N+ +
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEK---MVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQL 414
+ K QL ++ + +E + + + +T L + +E +++ D+ +L
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKRDIDDLEL 959
Query: 415 LWEAKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1061
>M57965-1|AAA51837.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 50.8 bits (116), Expect = 1e-05
Identities = 95/492 (19%), Positives = 197/492 (40%), Gaps = 44/492 (8%)
Query: 41 QQNVGVGDKTVAEL-KND-EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLY 98
Q N+ ++ +L KN ++ + ++++ LT K E + ++LK+
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 99 EDSASELEALKREN------IQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+D L +++E ++ T ++ + EII LT+ L + +L+++ E
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
D K N++TK + K E +++L S++ + V+ + A KL L
Sbjct: 1015 D-KVNTLTKAKV-----------KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-- 1060
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +++ + E D +++ + L + + L+E++ + E+
Sbjct: 1061 LTQESIMDLENDKQQLD-ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARI--EE 1117
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS---DLSKK----VNKTERE 324
L E E + + +++ L L + E +E ++E S +++KK K R+
Sbjct: 1118 LEEELESERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 1177
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYE 383
LEE Q L +S + + + ++ K ++ ELDD + N E
Sbjct: 1178 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-ME 1236
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL--ET 441
+I + L Q+NE + E ++ + DLT Q L+ +L +
Sbjct: 1237 QIIKAKANLEKMCRTLEDQMNEHRSKAE-----ETQRSVNDLTSQRAKLQTENGELSRQL 1291
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ KE LI Q RG T L+D ++ ++ + + Q+E+
Sbjct: 1292 DEKEALIS-QLTRG-KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349
Query: 502 LDDVMKQQQKEL 513
+ + Q+ L
Sbjct: 1350 ETEAKAELQRVL 1361
Score = 40.7 bits (91), Expect = 0.012
Identities = 50/260 (19%), Positives = 108/260 (41%), Gaps = 30/260 (11%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDL 314
ANLE+M L E++++E + K E ++ ++ L KL + E + + EK L+S L
Sbjct: 1243 ANLEKMCRTL-EDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL 1301
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++ ++LE+ + QL E+ +N +++ + + ++ + EL
Sbjct: 1302 TRGKLTYTQQLEDLKRQL----EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 1357
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+R+ L K + + T+ ET + L EAKK++A +
Sbjct: 1358 --------QRV---LSKANSEVAQWRTKY-ETDAIQRTEELEEAKKKLA----------Q 1395
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
RL + E + + + ++ + + ++D + + + E
Sbjct: 1396 RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1455
Query: 495 WKSQFEDLDDVMKQQQKELK 514
WK ++E+ ++ QKE +
Sbjct: 1456 WKQKYEESQSELESSQKEAR 1475
Score = 39.9 bits (89), Expect = 0.021
Identities = 60/311 (19%), Positives = 122/311 (39%), Gaps = 23/311 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLD-KLITKNETDINELRNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK ++ KL K+E RN ++ ++S+++ +
Sbjct: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E L + + E L N+ + D +
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 260 LEEMK--TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K +VE + + ++ + E + ++ +E ET + +L S +
Sbjct: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723
Query: 318 VN---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+N K + +L + Q ++ +++ + E + K I + + +A + K S L
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD----AAMMAEELKKEQDTSAHL 1779
Query: 375 DDESENTYERI 385
+ +N + I
Sbjct: 1780 ERMKKNMEQTI 1790
Score = 36.7 bits (81), Expect = 0.20
Identities = 92/409 (22%), Positives = 163/409 (39%), Gaps = 43/409 (10%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q ++ V + + L+ + + + I L L +K
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF-E 142
+ + K+ YE+S SELE+ ++E SL+ + L N + E
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKE---------------ARSLSTELFKLKNAYEE 1490
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
SLE LE ++N ++ IS L ++L + +T I+EL K LE+ K E +A E
Sbjct: 1491 SLEH--LETFKRENKNLQEEIS--DLTEQLGSSGKT-IHELEKVRKQLEAEKMELQSALE 1545
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ L + K Q E + +K E + L A+ + ++
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKL---------AEKDEEMEQAKRNHLRVVDS 1596
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
++T L E S + K E D LNE I N E + L + T+
Sbjct: 1597 LQTSLDAETRSRNEALRVKKKMEGD-LNEMEI-QLSHANRMAAEAQKQVKSLQSLLKDTQ 1654
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKL---IENMFNKVSQIASDFKISNQLSCELDDESE 379
+L++ L E + E + L +E + V Q K++ Q E + +
Sbjct: 1655 IQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ 1714
Query: 380 NTYERISLTLD---KITNHITYLNTQINE-TQKNDNAQLLWEAKKQIAD 424
+ + + ++ K+ ++ L T++ E Q+ NA+ +AKK I D
Sbjct: 1715 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE--EKAKKAITD 1761
Score = 35.5 bits (78), Expect = 0.46
Identities = 38/222 (17%), Positives = 98/222 (44%), Gaps = 6/222 (2%)
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+R + +M+E+ L + +K +ELEEK + L+++ ND + +N+ +
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEK---MVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQL 414
+ K QL ++ + +E + + + +T L + +E +++ D+ +L
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKRDIDDLEL 959
Query: 415 LWEAKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1061
>BC020645-1|AAH20645.1| 416|Homo sapiens Unknown (protein for
IMAGE:4659829) protein.
Length = 416
Score = 50.8 bits (116), Expect = 1e-05
Identities = 54/268 (20%), Positives = 113/268 (42%), Gaps = 16/268 (5%)
Query: 126 IIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITK--------NE 177
+ + ++I LT ++L E + + S+ K+NI +K ++ +TK +
Sbjct: 37 VTEGTGDIIKALTERLDALLPEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQ 96
Query: 178 TDIN---ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
+ IN E+ N L +V+S+Y+ L +QL A++ Q + E++ N+ +
Sbjct: 97 SHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKK 156
Query: 235 XXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLI 294
K + + K V + + I+ +++++ I+ L E+L+
Sbjct: 157 LQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELL 216
Query: 295 CDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF 354
+ E ++E L+ + + E E+ + E +L++Q +E N K E
Sbjct: 217 QLKAIHQEEVKE---LMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECEL 273
Query: 355 NKVSQIASDFKISNQLSCELDDESENTY 382
+ + S+ NQ+ L ENT+
Sbjct: 274 ENLRKATSNANQDNQICSIL--LQENTF 299
Score = 43.6 bits (98), Expect = 0.002
Identities = 77/344 (22%), Positives = 137/344 (39%), Gaps = 30/344 (8%)
Query: 18 IIHAFKIRLEECYKEIGQLKSGLQQNVGVGD--KTVAELKN---DEINSMIRQLXXXXXX 72
+I K R E KEIG+L+S G GD K + E + E +Q
Sbjct: 14 LIQKAKSRCTELEKEIGELRS-KPVTEGTGDIIKALTERLDALLPEKAETEQQCLSLKKE 72
Query: 73 XXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTE 132
+ + +T H +L++ + + E+E LK E + + + + L E
Sbjct: 73 NIKMKQEVEDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEE 132
Query: 133 VINTLTNGFESLEEVALEIDLKKNSITKDNI-SIKTLLDKLITKNETDINELRNSIKYLE 191
+NT ++ L LK + ++DN+ ++ ++K+ E I L+ +
Sbjct: 133 AMNT---------QLELSEQLKFQNNSEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATT 183
Query: 192 SVKSEYNTANEKLFEQLNNAVDKQ-NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXX 250
K E T + + E + K N +QEE+ LK +Q ++
Sbjct: 184 DEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQEEVK------ELMCQIEASA 237
Query: 251 XARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLN-EKLICDRREFNE----TMQ 305
+ I L E+K LV K E EK+ K E ++ N K + + N+ +Q
Sbjct: 238 KEHEAEINKLNELKENLV--KQCEASEKNIQKKYECELENLRKATSNANQDNQICSILLQ 295
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKL 349
E + +++KV E L+E + Q + L +++ N KL
Sbjct: 296 ENTFVEQVVNEKVKHLEDTLKELESQHSILKDEVTYMNNLKLKL 339
Score = 34.3 bits (75), Expect = 1.1
Identities = 71/364 (19%), Positives = 161/364 (44%), Gaps = 41/364 (11%)
Query: 107 ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIK 166
+LK+ENI+M E+ DS+T+ + + E++ + K+ ++K
Sbjct: 68 SLKKENIKMK-------QEVEDSVTK-----------MGDAHKELEQSHINYVKEIENLK 109
Query: 167 TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLK 226
L + +K D L+ ++ E++ ++ + + F+ NN+ D +QEE++ ++
Sbjct: 110 NELMAVRSKYSEDKANLQKQLE--EAMNTQLELSEQLKFQ--NNSEDNVKKLQEEIEKIR 165
Query: 227 --IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML--VEEKLSEIKEKDENF 282
E Q L ++ AN + + + ++E+L ++K +
Sbjct: 166 PGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQ-- 223
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQE-QLTHLMEQL-N 340
+E+ L ++ +E + + N L +L K+ +E+ +++K E +L +L + N
Sbjct: 224 -EEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSN 282
Query: 341 DTENN---SYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLT-LDKITNHI 396
++N S L EN F V Q+ ++ K+ + + ES+++ + +T ++ + +
Sbjct: 283 ANQDNQICSILLQENTF--VEQVVNE-KVKHLEDTLKELESQHSILKDEVTYMNNLKLKL 339
Query: 397 TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
I + ++ L ++ + + EQ ++++ S+L NK+ TV
Sbjct: 340 EMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQF---CYTVEQH 396
Query: 457 NEEV 460
N EV
Sbjct: 397 NREV 400
>AY131226-1|AAN07912.1| 681|Homo sapiens medulloblastoma antigen
MU-MB-20.201 protein.
Length = 681
Score = 50.8 bits (116), Expect = 1e-05
Identities = 66/309 (21%), Positives = 132/309 (42%), Gaps = 25/309 (8%)
Query: 149 LEIDLKKNSITKDNISIKTLL-DKLITKNETDINELRNSIKYLESVKSEYNTAN-EKLFE 206
L ++ KN + ++ ++K +L DKL T N+ +I L++ ++ KSE + E L
Sbjct: 62 LNLEEDKNQLQQELENLKEVLEDKLNTANQ-EIGHLQDMVR-----KSEQGLGSAEGLIA 115
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
L D Q +Q E+DL K +L + ++ IA ++E + +
Sbjct: 116 SLQ---DSQERLQNELDLTK---DSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKL 169
Query: 267 LVEEKLSEIKEK-DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
V++ +++ K EN +QE L E+L E ++ + + L D K +
Sbjct: 170 KVDKMAHDLEIKWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKNAAR----- 224
Query: 326 EEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI 385
+ Q+++ L+ Q++ + N + + Q+ + F Q + +E E +++
Sbjct: 225 DSWQKKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQAQFTQERQRLTQELEELEEQHQQR 284
Query: 386 SLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
+L + H+ T E +K A +K A+L +E + E ++
Sbjct: 285 HKSLKEA--HVLAFQTMEEEKEKEQRALENHLQQKHSAELQSLKDAHRESMEGFRIEMEQ 342
Query: 446 LLIEIQTVR 454
E+QT+R
Sbjct: 343 ---ELQTLR 348
Score = 33.1 bits (72), Expect = 2.4
Identities = 63/276 (22%), Positives = 112/276 (40%), Gaps = 22/276 (7%)
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
EL+N LE ++ N A+ K E+L K + E V I ++ LQ
Sbjct: 1 ELKNLQSRLEEEVTQLNEAHSKTLEEL---AWKHHMAIEAVHSNAIRDKKKLQMDLEEQH 57
Query: 242 XXXXXXXXXXARDKFIANLEEMKTMLVEEKLS----EIKEKDENFKQEIDMLN--EKLIC 295
+++ LE +K +L E+KL+ EI + ++ L E LI
Sbjct: 58 NKDKLNLEED-KNQLQQELENLKEVL-EDKLNTANQEIGHLQDMVRKSEQGLGSAEGLIA 115
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
++ E +Q + L D K+ +E + EQ E+ KL
Sbjct: 116 SLQDSQERLQNELDLTKDSLKETKDALLNVEGELEQERQQHEETIAAMKEEEKL------ 169
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLL 415
KV ++A D +I + + L E E + L ++ Q+ + +KN A+
Sbjct: 170 KVDKMAHDLEI--KWTENLRQECSKLREELRLQHEEDKKSAMSQLLQLKDREKN-AARDS 226
Query: 416 WEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ 451
W+ K++ DL Q +LK+ L ++++ L ++Q
Sbjct: 227 WQ--KKVEDLLNQISLLKQNLEIQLSQSQTSLQQLQ 260
>AF007217-1|AAD09135.1| 1978|Homo sapiens Trip230 protein.
Length = 1978
Score = 50.8 bits (116), Expect = 1e-05
Identities = 78/408 (19%), Positives = 171/408 (41%), Gaps = 32/408 (7%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKREN----IQMHTSDVMVVPEIIDSLTEVINTL 137
+KLT +H + YE+ ELE L ++ I+ S + + + I L
Sbjct: 245 QKLTEISRRHREELSDYEERIEELENLLQQGGSGVIETDLSKIYEMQKTIQVLQIEKVES 304
Query: 138 TNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRN-----SIKYLES 192
T E LE+ +I+ K +S D ++ ++L + + E N S +
Sbjct: 305 TKKMEQLEDKIKDINKKLSSAENDRDILRREQEQLNVEKRQIMEECENLKLECSKLQPSA 364
Query: 193 VK-SEYNTANEKLFEQLNNAVD----KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
VK S+ T E++ Q + + +Q E +++++ + N
Sbjct: 365 VKQSDTMTEKERILAQSGSVEEVFRLRQALSDAENEIMRLSSLNQDNSLAEDNLKLKMRI 424
Query: 248 XXXXARDKFIA-NLEEMKTMLVE-----EKLSEIKEKDENFKQEIDMLNEKLICDRREFN 301
++ EE++ L++ E + +D + E+ L L +E N
Sbjct: 425 EVLEKEKSLLSQEKEELQMSLLKLNNEYEVIKSTATRDISLDSELHDLRLNLEAKEQELN 484
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
+++ EK L+++ + + +R+ +E + + + QL+ +N +++ +K+ Q
Sbjct: 485 QSISEKETLIAE----IEELDRQNQEATKHMILIKAQLSKQQNEG----DSIISKLKQDL 536
Query: 362 SDFKIS-NQLSCE-LDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
+D K +QL + +D E + + L ++ + +L Q E + + L +++
Sbjct: 537 NDEKKRVHQLEDDKMDITKELDVQFVLLIQSEVALNDLHLTKQKLEDKVENLVDQLNKSQ 596
Query: 420 KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS 467
+ + ++N+ LKE + Q E E + E+ ++ N++ N KD+
Sbjct: 597 ESNVSIQKENLELKEHIRQNEEELSRIRNEL--MQSLNQDSNSNFKDT 642
Score = 47.6 bits (108), Expect = 1e-04
Identities = 106/530 (20%), Positives = 206/530 (38%), Gaps = 41/530 (7%)
Query: 27 EECYKEIGQLKSGLQQNVGVGDKTVAELKND--EINSMIRQLXXXXXXXXXXXXXLTEKL 84
+E K + +K+ L + GD +++LK D + + QL L
Sbjct: 505 QEATKHMILIKAQLSKQQNEGDSIISKLKQDLNDEKKRVHQLEDDKMDITKELDVQFVLL 564
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+E NDL + ++E L + + S+V + E ++ +
Sbjct: 565 IQSEVALNDLHLTKQKLEDKVENLVDQLNKSQESNVSIQKENLELKEHIRQNEEELSRIR 624
Query: 145 EEVALEIDLKKNSITKDNISIKTLLD-KLITKNETDINELRNSIKYLE-SVKSEYNT--- 199
E+ ++ NS KD + + + + + +N +++ +L ++K + VK E
Sbjct: 625 NELMQSLNQDSNSNFKDTLLKEREAEVRNLKQNLSELEQLNENLKKVAFDVKMENEKLVL 684
Query: 200 ANEKLFEQLNNAVDKQNCIQEE----VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDK 255
A E + QL + N + E V+ LK+E + +
Sbjct: 685 ACEDVRHQLEECLAGNNQLSLEKNTIVETLKMEKGEIEAELCWAKKRLLEEANKYEKTIE 744
Query: 256 FIANLEEMKT---MLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
++N + T L E L ++ +K + E+ E++ D +E + +
Sbjct: 745 ELSNARNLNTSALQLEHEHLIKLNQKKDMEIAELKKNIEQMDTDHKETKDVLSSSLEEQK 804
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK---LIENMFNKVSQIASDFKISNQ 369
L++ +NK E +E+ +E+ + L E+L+ K L + + K + S + +N
Sbjct: 805 QLTQLINKKEIFIEKLKERSSKLQEELDKYSQALRKNEILRQTIEEKDRSLGSMKEENNH 864
Query: 370 LSCEL----DDESENTYERISLTLDKIT---NHITYLNT-------------QINETQKN 409
L EL +++S TLD +T + ++ LNT +I E Q
Sbjct: 865 LQEELERLREEQSRTAPVADPKTLDSVTELASEVSQLNTIKEHLEEEIKHHQKIIEDQNQ 924
Query: 410 DNAQL---LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQ-TVRGSNEEVTLNLK 465
QL L E KK++ + Q+ + +QL E E + +Q T+ ++ +
Sbjct: 925 SKMQLLQSLQEQKKEMDEFRYQHEQMNATHTQLFLEKDEEIKSLQKTIEQIKTQLHEERQ 984
Query: 466 DSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
D T S IE+ K K++ E L +K+++ E+KL
Sbjct: 985 DIQTDNSDIFQETKVQSLNIENGSEKHDLSKAETERLVKGIKERELEIKL 1034
Score = 32.3 bits (70), Expect = 4.2
Identities = 80/397 (20%), Positives = 165/397 (41%), Gaps = 59/397 (14%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
ES E + E++ + S+ + + +I+TL + + + L +SI ++ + +
Sbjct: 1340 ESSELLQQELEELRKSLQEKDATIRTL--------QENNHRLSDSIAATSELERKEHEQT 1391
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLL-KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
+ +QL D + +E DLL K ++ LL A + NL
Sbjct: 1392 DSEIKQLKEKQDVLQKLLKEKDLLIKAKSDQLLSSNENFTNKVNENELLRQA----VTNL 1447
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEI---DMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+E + +++E + ++K ++E + + + L +F+ ++EK + +K
Sbjct: 1448 KE-RILILEMDIGKLKGENEKIVETYRGKETEYQALQETNMKFSMMLREKEFECHSMKEK 1506
Query: 318 VNKTERELEEKQE----QLTHLMEQLNDTENNS---------------YKLIEN--MFNK 356
E+ L+EK++ +L L+ + + + K +EN + N+
Sbjct: 1507 ALAFEQLLKEKEQGKTGELNQLLNAVKSMQEKTVVFQQERDQVMLALKQKQMENTALQNE 1566
Query: 357 VSQIASDFKISNQLSCELDD---ESENTYERISLTLD----KITNHITYLNTQ-INETQK 408
V ++ SNQ L + ESE++Y R +L + K+ +T L + ++ +
Sbjct: 1567 VQRLRDKEFRSNQELERLRNHLLESEDSYTREALAAEDREAKLRKKVTVLEEKLVSSSNA 1626
Query: 409 NDNAQLLWEAKKQIADLTEQ-NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD- 466
+NA +A Q+ L EQ N++ K+R E + + G+ ++ L+L +
Sbjct: 1627 MENAS--HQASVQVESLQEQLNVVSKQR--------DETALRF-CLSGTVKQYRLSLANL 1675
Query: 467 SSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLD 503
S E+E K + EWK E+L+
Sbjct: 1676 QMVLEHFQQEEKAMYSAELEKQKQLIAEWKKNAENLE 1712
>Z22551-1|CAA80271.1| 1356|Homo sapiens 156 kDa Protein protein.
Length = 1356
Score = 50.4 bits (115), Expect = 1e-05
Identities = 79/482 (16%), Positives = 202/482 (41%), Gaps = 31/482 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K A D + +++ + +++ E +HN + S E + +
Sbjct: 344 KEDAAATKDRCKQLTQEMMTEKERSNVVMTRMKDRIGTLEKEHNVFQNKIHVSYQETQQM 403
Query: 109 KRENIQMHT---SDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISI 165
+ + Q+ +++ + + L + ++ TN ES + L N + +D +
Sbjct: 404 QMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAEL------NKLRQDYARL 457
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNC----IQEE 221
L + K + + + +N+ + +K + A E+ +E++ + + K+ Q++
Sbjct: 458 VNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEA-ERRWEEVQSYIRKRTAEHEAAQQD 516
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE---KLSEIKEK 278
+ + +N +Q R + E+ + E ++ +I E+
Sbjct: 517 LQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQ 576
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+E K +I + + I + + +E + ++++ K++ +TE L ++++LT E+
Sbjct: 577 NEALKAQIQQFHSQ-IAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 635
Query: 339 LNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY---ERISLTLDKITNH 395
L D +N ++ L++ K+ +A++ + EL+ ++ Y ++I L +++ +
Sbjct: 636 LKDIQNMNF-LLKAEVQKLQALANE---QAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 691
Query: 396 ITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRG 455
I+ + + + N L E +K ++EQ K+ + Q+E +E +++TV
Sbjct: 692 ISNKMEEF-KILNDQNKALKSEVQKLQTLVSEQP--NKDVVEQMEKCIQEKDEKLKTVEE 748
Query: 456 SNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK---VMEWKSQFEDLDDVMKQQQKE 512
E + + + E++D+K K + + S E+L V+ ++ +
Sbjct: 749 LLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGK 808
Query: 513 LK 514
+K
Sbjct: 809 IK 810
Score = 46.0 bits (104), Expect = 3e-04
Identities = 64/355 (18%), Positives = 147/355 (41%), Gaps = 27/355 (7%)
Query: 20 HAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKN-DEINSMIRQLXXXXXXXXXXXX 78
H ++EE +K + L+ V V+E N D + M + +
Sbjct: 690 HEISNKMEE-FKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEE 748
Query: 79 XLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L L TK +L + +++S + + ++++ +D + +++ L +VI+
Sbjct: 749 LLETGLIQVATKEEELNAIRTENSSLTKEV--QDLKAKQNDQVSFASLVEELKKVIHEKD 806
Query: 139 NGFESLEEVA----LEIDLKKNSITKDNISIKTLLDKL----ITKNE-----TDINELRN 185
+S+EE+ L++ K+ ++ IK L +++ + K + + + EL+N
Sbjct: 807 GKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQN 866
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
+K E + E+ + L N +QEE + LK Q + Q
Sbjct: 867 LLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQ 926
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEK---------LSEIKEKDENFKQEIDMLNEKLICD 296
+ L+ ++ ML E + L +++++++ FK +I+ L ++
Sbjct: 927 FEELEIVLKEKGNELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQ 986
Query: 297 RREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIE 351
F +E ++S+ K+++ EL+ ++ + H ++ ND +++ +E
Sbjct: 987 ASSF-PPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAME 1040
Score = 41.9 bits (94), Expect = 0.005
Identities = 76/335 (22%), Positives = 147/335 (43%), Gaps = 46/335 (13%)
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD----KFIANLEEMKTM 266
A ++ +E +L I+N N L A + + +++ K
Sbjct: 623 ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIR 682
Query: 267 LVEEKLS-EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK--VNKTER 323
L+EE+L EI K E FK +LN++ + +Q+ L+S+ K V + E+
Sbjct: 683 LLEEQLQHEISNKMEEFK----ILNDQ----NKALKSEVQKLQTLVSEQPNKDVVEQMEK 734
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
++EK E+L +E+L +T LI+ + K ++ + ++ L+ E+ D +
Sbjct: 735 CIQEKDEKLK-TVEELLETG-----LIQ-VATKEEELNAIRTENSSLTKEVQDLKAKQND 787
Query: 384 RISLT--LDKITNHITYLNTQINETQKNDNAQLLWEAKKQ--IADLTEQNIILKERLSQL 439
++S ++++ I + +I ++ A+LL A K+ + DL ++ LKE + +
Sbjct: 788 QVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNV 847
Query: 440 ETENKELLI------EIQTV-RGSNEEV-TLN--LKDSSTXXXXXXXXXXXXSNEIEDMK 489
+ E + L E+Q + +G E++ T+ L++ E E +K
Sbjct: 848 QLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 907
Query: 490 TKVMEWK----------SQFEDLDDVMKQQQKELK 514
V E SQFE+L+ V+K++ ELK
Sbjct: 908 AHVQEVAQHNLKEASSASQFEELEIVLKEKGNELK 942
Score = 37.1 bits (82), Expect = 0.15
Identities = 23/91 (25%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 253 RDKFIANLEEMKTMLVEEK-LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+ F ++ +E++ + E K + ++ + E+ + E+ EK +R + ++E LL
Sbjct: 1178 QSSFTSSEQELERLRSENKDIENLRREREHLEMEL----EKAEMERSTYVTEVRELKDLL 1233
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
++L KK++ + E + E+L L QLN+T
Sbjct: 1234 TELQKKLDDSYSEAVRQNEELNLLKAQLNET 1264
Score = 32.7 bits (71), Expect = 3.2
Identities = 38/193 (19%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 160 KDNISIKTLLDKLITKNETDINELRNSIKYLE-SVKSEYNTANEKLFEQLNNAVDKQNCI 218
K+ + TLL K ++ + E ++ L+ SV+ E N K+ E Q+
Sbjct: 1122 KEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSF 1181
Query: 219 ---QEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEI 275
++E++ L+ EN+++ R ++ + E+K +L +E+
Sbjct: 1182 TSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLL-----TEL 1236
Query: 276 KEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK---KVNKTERELEEKQEQL 332
++K ++ E NE+L + + NET+ + ++ K ++K ++ LE Q ++
Sbjct: 1237 QKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1296
Query: 333 THLMEQLNDTENN 345
EN+
Sbjct: 1297 VKAAGDTTVIENS 1309
>X69292-1|CAA49154.1| 881|Homo sapiens smooth muscle mysosin heavy
chain protein.
Length = 881
Score = 50.4 bits (115), Expect = 1e-05
Identities = 81/441 (18%), Positives = 175/441 (39%), Gaps = 31/441 (7%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K E K ++ + +++L L +K+ + + + + ++ + L
Sbjct: 156 KQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKL 215
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV--ALEIDLKKNSITKDNIS-- 164
++ + +S + E++ T ++ LEE +L+ L + K N+
Sbjct: 216 AKDVASL-SSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERH 274
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN---AVDK----QNC 217
I TL +L + ++ + + ++++ LE K + E L +Q A DK +N
Sbjct: 275 ISTLNIQL-SDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 333
Query: 218 IQEEVD--LLKIENQNLL---------QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM 266
+Q+E+D ++ ++NQ L + RD+ A E +T
Sbjct: 334 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 393
Query: 267 LVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
+ L+ E+ K+E++ N+ L + + + + + +L K E ++E
Sbjct: 394 ALS--LARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQME 451
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERIS 386
E + QL L ++L TE+ +L NM Q D + ++ + E + +
Sbjct: 452 EMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYE 511
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
L+ L + + D L +A I E+ I ++L +L+ + K+
Sbjct: 512 TELEDERKQ-RALAAAAKKKLEGDLKDLELQADSAIKG-REEAI---KQLRKLQAQMKDF 566
Query: 447 LIEIQTVRGSNEEVTLNLKDS 467
E++ R S +E+ K++
Sbjct: 567 QRELEDARASRDEIFATAKEN 587
Score = 46.8 bits (106), Expect = 2e-04
Identities = 57/351 (16%), Positives = 144/351 (41%), Gaps = 19/351 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQL---NNAVDKQNCIQEEVDLL 225
L + + + +I + N++K + ++ + E L + N A ++ + EE++ L
Sbjct: 1 LQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEAL 60
Query: 226 KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQE 285
K E ++ L K + V+E + + E ++
Sbjct: 61 KTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQ 120
Query: 286 IDMLNE-KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTEN 344
++ K D+ + +T++++N L+ + + + ++E+E K+++L +++L +
Sbjct: 121 LEQFKRAKANLDKNK--QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCS 178
Query: 345 NSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQIN 404
+ + + +KV K+ N++ +E + I L D + L++Q+
Sbjct: 179 DGERARAELNDKVH------KLQNEVESVTGMLNEAEGKAIKLAKD-----VASLSSQLQ 227
Query: 405 ETQK--NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL 462
+TQ+ + + ++ L E+ L+++L + + L I T+ +
Sbjct: 228 DTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKK 287
Query: 463 NLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
L+D ++ EIE++ + E + ++ L+ + Q+EL
Sbjct: 288 KLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQEL 338
Score = 44.4 bits (100), Expect = 0.001
Identities = 78/424 (18%), Positives = 177/424 (41%), Gaps = 47/424 (11%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNI 163
E+ LK+ + S V E+ + + LT E + +D K ++ K+N
Sbjct: 84 EVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENA 143
Query: 164 SIKTLLDKLITKNETDINELRNSIK-YLESVKSEYNTANEKLFEQLNNAVDK-QNCIQEE 221
+ L +++ + + ++ + ++ ++ ++S+ + E+ +LN+ V K QN ++
Sbjct: 144 DLAGEL-RVLGQAKQEVEHKKKKLEAQVQELQSKCSDG-ERARAELNDKVHKLQNEVESV 201
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN 281
+L N + + + E + + V KL +++E+ +
Sbjct: 202 TGML-----NEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNS 256
Query: 282 FKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN---KTERELEEKQEQLTHLMEQ 338
+ ++D E ++ + NI LSD KK+ T LEE +++ +E
Sbjct: 257 LQDQLDEEMEA----KQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIEN 312
Query: 339 LN---DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE--NTYERISLTLDKIT 393
L + + +Y +E N++ Q D + +LD++ + + E+ D++
Sbjct: 313 LTQQYEEKAAAYDKLEKTKNRLQQELDDLVV------DLDNQRQLVSNLEKKQRKFDQLL 366
Query: 394 NHITYLNTQINETQKNDNAQLLWEAKK--QIADLTEQNIILKERLSQLETENKELLIEIQ 451
++++ + + A+ + K +A E+ + KE +LE NK L E++
Sbjct: 367 AEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKE---ELERTNKMLKAEME 423
Query: 452 TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+ S ++V N+ + ++T++ E K+Q E+L+D + Q +
Sbjct: 424 DLVSSKDDVGKNVHELEKSKRA--------------LETQMEEMKTQLEELEDEL-QATE 468
Query: 512 ELKL 515
+ KL
Sbjct: 469 DAKL 472
Score = 42.7 bits (96), Expect = 0.003
Identities = 69/328 (21%), Positives = 135/328 (41%), Gaps = 30/328 (9%)
Query: 148 ALEIDLK-KNSITKDNISIKTLLDKLITKNET---DINELRNSIKYLESVKSEYNTANEK 203
ALE L+ K + + N +K ++ L++ + +++EL S + LE+ E T E+
Sbjct: 400 ALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEE 459
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM 263
L ++L D + ++ + LK + + LQ R + L E
Sbjct: 460 LEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEK---------RRQLQRQLHEY 510
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
+T L +E+ K E D+ + +L D + +E L L ++ +R
Sbjct: 511 ETELEDERKQRALAAAAKKKLEGDLKDLELQADSAI--KGREEAIKQLRKLQAQMKDFQR 568
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
ELE+ + + + E + L ++ +A+ + Q E ++ +E
Sbjct: 569 ELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELAS 628
Query: 384 RIS----LTLDK--ITNHITYLNTQINETQKN-----DNAQLLWEAKKQIAD--LTEQNI 430
+S L +K + I L ++ E Q N D + + +Q+++ TE++
Sbjct: 629 SLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERST 688
Query: 431 ILKERLS--QLETENKELLIEIQTVRGS 456
K S QLE +NKEL ++ + G+
Sbjct: 689 AQKNESSRQQLERQNKELRSKLHEMEGA 716
Score = 37.5 bits (83), Expect = 0.11
Identities = 42/201 (20%), Positives = 85/201 (42%), Gaps = 12/201 (5%)
Query: 252 ARDKFIANLEE--MKTMLVEEKLSEIKEK---DENFKQEIDMLNEKLICDRREFNETMQE 306
+RD+ A +E K +E L +++E E +++ D+ E+L E ++
Sbjct: 576 SRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELA---EELASSLSG 632
Query: 307 KNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+N L + L ++ + E ELEE+Q + + +++ + +L + + S +
Sbjct: 633 RNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKN 692
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
QL + + +E K + I L +I + ++ Q E +
Sbjct: 693 ESSRQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVE-QEAREKQAATK 751
Query: 424 DLTEQNIILKERLSQLETENK 444
L +++ LKE L Q+E E K
Sbjct: 752 SLKQKDKKLKEILLQVEDERK 772
Score = 36.7 bits (81), Expect = 0.20
Identities = 43/237 (18%), Positives = 98/237 (41%), Gaps = 15/237 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E D+ +L+ + E + + + E+L E+L +++ +N +Q+E L+ + Q
Sbjct: 595 EADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLE---ARIAQLE 651
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICD 296
K E++ L E+ +K+E+ +Q+++ N++L
Sbjct: 652 EELEEEQGNMEAMSDRVRKATQQAEQLSNELATER--STAQKNESSRQQLERQNKELRSK 709
Query: 297 RREFNETMQEK-NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKL---IEN 352
E ++ K ++ L K+ + E ++E++ + + L + ++ +E+
Sbjct: 710 LHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVED 769
Query: 353 MFNKVSQIASDFKISN----QLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
Q + N QL +L +E+E +RI+ K+ + T+ NE
Sbjct: 770 ERKMAEQYKEQAEKGNARVKQLKRQL-EEAEEESQRINANRRKLQRELDEA-TESNE 824
>M31013-1|AAA36349.1| 1247|Homo sapiens protein ( Human nonmuscle
myosin heavy chain (NMHC) mRNA, 3' end. ).
Length = 1247
Score = 50.4 bits (115), Expect = 1e-05
Identities = 80/427 (18%), Positives = 172/427 (40%), Gaps = 27/427 (6%)
Query: 107 ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIK 166
A + ++M T ++ E + L E + T EE+ + KK + + ++
Sbjct: 149 AAENRLMEMETLQSQLMAEKLQ-LQEQLQAETELCAEAEELRARLTAKKQELEEICHDLE 207
Query: 167 TLLDKLITKNE---TDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVD 223
+++ + + + +++ +I+ LE E +A +KL + K ++EE
Sbjct: 208 ARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQI 267
Query: 224 LLKIENQNLL---QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDE 280
+L+ +N L + + K +A L+ ++ + L E ++E
Sbjct: 268 ILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD-LEERLRREE 326
Query: 281 NFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL-------EEKQEQLT 333
+QE++ KL D + ++ + E +++L ++ K E EL EE+ Q
Sbjct: 327 KQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKN 386
Query: 334 HLMEQLNDTENNSYKLIENM------FNKVSQIASDF-KISNQLSCELDDESENTYERIS 386
++++ + E+ +L E++ NK + D + L EL+D ++T +
Sbjct: 387 MALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQE 446
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
L K + L + E K AQ + E +++ + E+ L E+L Q + L
Sbjct: 447 LR-SKREQEVNILKKTLEEEAKTHEAQ-IQEMRQKHSQAVEE---LAEQLEQTKRVKANL 501
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVM 506
QT+ E+ +K ++++++ K E + +L D +
Sbjct: 502 EKAKQTLENERGELANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKV 561
Query: 507 KQQQKEL 513
+ Q EL
Sbjct: 562 TKLQVEL 568
Score = 46.0 bits (104), Expect = 3e-04
Identities = 91/505 (18%), Positives = 200/505 (39%), Gaps = 36/505 (7%)
Query: 25 RLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKL 84
++ E +I +L+ L+ +K AE + ++ + L E
Sbjct: 391 KIRELESQISELQEDLESERASRNK--AEKQKRDLGEELEALKTELEDTLDSTAAQQELR 448
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+ E + N LKK E+ A EA +E Q H+ V + E ++ V L ++L
Sbjct: 449 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 508
Query: 145 E----EVALEIDL------------KKNSITKDNISIK-TLLDKLITKNETDINELRNSI 187
E E+A E+ + KK + +K +++ T+ + +L+ +
Sbjct: 509 ENERGELANEVKVLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 568
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXX----XXXXXX 243
+ + S+ ++ + KL + +A++ Q +Q+ +LL+ EN+ L
Sbjct: 569 DNVTGLLSQSDSKSSKLTKDF-SALESQ--LQDTQELLQEENRQKLSLSTKLKQVEDEKN 625
Query: 244 XXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN---FKQEIDMLNEKLICDRREF 300
++ NLE+ L +++++K+K E+ + + + KL D
Sbjct: 626 SFREQLEEEEEEAKHNLEKQIATL-HAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGL 684
Query: 301 NETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
++ +EK L K + ++EL++ L H + + E K + + + I
Sbjct: 685 SQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ-KKFDQLLAEEKTI 743
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDKITN---HITYLNTQINETQKNDNAQLLWE 417
++ + + E E ++ L++ + LN Q T+ D +
Sbjct: 744 SAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQF-RTEMEDLMSSKDD 802
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
K + +L + L++++ +++T+ +EL E+Q + + +NL+
Sbjct: 803 VGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQG 862
Query: 478 XXXXSNE-IEDMKTKVMEWKSQFED 501
S E + + +V E +++ ED
Sbjct: 863 RDEQSEEKKKQLVRQVREMEAELED 887
Score = 45.6 bits (103), Expect = 4e-04
Identities = 78/392 (19%), Positives = 161/392 (41%), Gaps = 36/392 (9%)
Query: 157 SITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQN 216
++T++ K+L KL K+E I +L ++ E + E KL + D+
Sbjct: 293 NLTEEEEKSKSLA-KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 351
Query: 217 CIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIK 276
+Q ++ LK++ + K I LE + L E+ SE
Sbjct: 352 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 411
Query: 277 EKDENFKQEIDMLNEKLICDRREFNETM--------------QEKNILLSDLSKKVNKTE 322
+++ KQ+ D L E+L + E +T+ QE NIL L ++ E
Sbjct: 412 SRNKAEKQKRD-LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 470
Query: 323 RELEEKQ-------EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+++E + E+L +EQ + N K + + N+ ++A++ K+ Q + +
Sbjct: 471 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGGRDSE 530
Query: 376 DES---ENTYERISLTLDKITNHITYLNTQINETQ-KNDNAQ-LLWEAKKQIADLTEQNI 430
+ E + + + ++ T L ++ + Q + DN LL ++ + + LT+
Sbjct: 531 HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS 590
Query: 431 ILKERLSQ----LETENKE---LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
L+ +L L+ EN++ L +++ V L++ +
Sbjct: 591 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQIATLH 650
Query: 484 -EIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
++ DMK K+ + E ++V ++ QK+L+
Sbjct: 651 AQVADMKKKMEDSVGCLETAEEVKRKLQKDLE 682
Score = 45.6 bits (103), Expect = 4e-04
Identities = 73/431 (16%), Positives = 168/431 (38%), Gaps = 18/431 (4%)
Query: 40 LQQNVGVGDKTVAEL--KNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKL 97
LQ G++ EL K ++ + + LT+ + E++ D ++L
Sbjct: 543 LQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQEL 602
Query: 98 YEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNS 157
++ + +L + Q+ ++ + E + L +L A D+KK
Sbjct: 603 LQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEAKHNLEKQIATLH--AQVADMKKKM 660
Query: 158 ITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA-VDKQN 216
+D++ +++ K + D+ L + + + +L ++L++ VD +
Sbjct: 661 --EDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDH 718
Query: 217 CIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIK 276
Q +L K Q R + A +E K + + L E
Sbjct: 719 QRQSACNLEK--KQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAM 776
Query: 277 EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLM 336
E+ K E++ LN++ + + + + + +L K E+++EE + QL L
Sbjct: 777 EQ----KAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELE 832
Query: 337 EQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHI 396
++L TE+ +L N+ +Q D + ++ S +++ + ++ ++ +
Sbjct: 833 DELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQS---EEKKKQLVRQVREMEAELEDER 889
Query: 397 TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
+ + +K + EA A+ I ++L +L+ + K+ + E+ R S
Sbjct: 890 KQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAI--KQLRKLQAQMKDCMRELDDTRAS 947
Query: 457 NEEVTLNLKDS 467
EE+ K++
Sbjct: 948 REEILAQAKEN 958
Score = 45.2 bits (102), Expect = 6e-04
Identities = 55/255 (21%), Positives = 110/255 (43%), Gaps = 24/255 (9%)
Query: 269 EEKLSEIKEKDENFKQ---EIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
EE L++ KE ++ K E+ L E+L R + QE++ L +++ K L
Sbjct: 949 EEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAL 1008
Query: 326 EEK---QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
EEK + ++ L E+L + + N+ +LI + K + + D +I+ L+ E +N
Sbjct: 1009 EEKRRLEARIAQLEEELEEEQGNT-ELINDRLKK-ANLQID-QINADLNLERGHAQKN-- 1063
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
E L++ + ++ T K+ + + +IA L E QL+ E
Sbjct: 1064 ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE----------QLDNE 1113
Query: 443 NKELLIEIQTVRGSN---EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQF 499
KE + VR + ++V L + D S ++ +K ++ E + +
Sbjct: 1114 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1173
Query: 500 EDLDDVMKQQQKELK 514
+ + ++ Q+EL+
Sbjct: 1174 QRANASRRKLQRELE 1188
Score = 44.4 bits (100), Expect = 0.001
Identities = 76/465 (16%), Positives = 184/465 (39%), Gaps = 40/465 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L E L N +K D ELEALK E ++ E+ + +N L
Sbjct: 402 LQEDLESERASRNKAEKQKRDLGEELEALKTE-LEDTLDSTAAQQELRSKREQEVNILKK 460
Query: 140 GFES---LEEVALEIDLKKNSITKDNIS--------IKTLLDKLITKNETDINELRNSIK 188
E E ++ +K+S + ++ +K L+K E + EL N +K
Sbjct: 461 TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVK 520
Query: 189 YL-------ESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
L E + + ++L + N + + ++V L++E N+
Sbjct: 521 VLLQGGRDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDS 580
Query: 242 XXXXXXXXXXARDKFIANLEEM------KTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC 295
A + + + +E+ + + + KL +++++ +F+++++ E+
Sbjct: 581 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEEA-- 638
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+ + + + ++D+ KK+ + LE +E L + L + + ++
Sbjct: 639 -KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA-AYD 696
Query: 356 KVSQIASDFKIS-NQLSCELDDESENT--YERISLTLDKITNHITYLNTQINETQKNDNA 412
K+ + + + + L +LD + ++ E+ D++ ++ + E + A
Sbjct: 697 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 756
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
+ + K ++ L E+ ++LE NK+ E++ + S ++V ++ +
Sbjct: 757 EAREKETKALS-LARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 815
Query: 473 XXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
++E+MKT++ E + + + +D + + L+ K
Sbjct: 816 AL-------EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMK 853
Score = 43.2 bits (97), Expect = 0.002
Identities = 54/257 (21%), Positives = 115/257 (44%), Gaps = 20/257 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+ K ++L E E++E+ +Q++ + EK+ + + + ++E+ I+L D + K+ K
Sbjct: 223 EKKKMQQNIQELEEQLEEEESARQKLQL--EKVTTEAKL--KKLEEEQIILEDQNCKLAK 278
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
++ LE++ + T L + E S K + + NK + +D + +L E E
Sbjct: 279 EKKLLEDRIAEFT---TNLTEEEEKS-KSLAKLKNKHEAMITD--LEERLRRE-----EK 327
Query: 381 TYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
+ + T K+ T L+ QI E Q AQ+ E K Q+A E+ R+ +
Sbjct: 328 QRQELEKTRRKLEGDSTDLSDQIAELQ----AQIA-ELKMQLAKKEEELQAALARVEEEA 382
Query: 441 TENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
+ L +I+ + E+ +L+ E+E +KT++ +
Sbjct: 383 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 442
Query: 501 DLDDVMKQQQKELKLGK 517
++ ++++E+ + K
Sbjct: 443 AQQELRSKREQEVNILK 459
Score = 40.3 bits (90), Expect = 0.016
Identities = 49/282 (17%), Positives = 122/282 (43%), Gaps = 32/282 (11%)
Query: 261 EEMKTMLVEEKLSEIKEKD---ENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---- 313
+E + M EE+L +++EK EN E++ L +L+ ++ + E +Q + L ++
Sbjct: 129 QEEEMMAKEEELVKVREKQLAAENRLMEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 188
Query: 314 ----------LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----- 358
L + + E +EE++E+ HL + + N +L E + + S
Sbjct: 189 RARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKMQQNIQELEEQLEEEESARQKL 248
Query: 359 ---QIASDFKIS--NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQ-----K 408
++ ++ K+ + L+D++ + L D+I T L + +++ K
Sbjct: 249 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 308
Query: 409 NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
N + ++ + ++++ +Q L++ +LE ++ +L +I ++ E+ + L
Sbjct: 309 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 368
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQ 510
+ + K+ E +SQ +L + ++ ++
Sbjct: 369 EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 410
Score = 32.3 bits (70), Expect = 4.2
Identities = 33/134 (24%), Positives = 64/134 (47%), Gaps = 8/134 (5%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
+V++ E E+ K+E+L + E+ EN +L+E + +A ++ QL E +
Sbjct: 125 QVSRQEEEMMAKEEELVKVREKQLAAEN---RLMEMETLQSQLMAEKLQLQEQLQAETEL 181
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
+E R LT K + + ++ + Q L KK++ +QNI L+E+
Sbjct: 182 CAEAEELRARLTAKKQELEEICHDLEARVEEEEERYQHLQAEKKKM----QQNIQELEEQ 237
Query: 436 LSQLETENKELLIE 449
L + E+ ++L +E
Sbjct: 238 LEEEESARQKLQLE 251
>L25616-1|AAB65853.1| 1300|Homo sapiens kinectin protein.
Length = 1300
Score = 50.4 bits (115), Expect = 1e-05
Identities = 79/482 (16%), Positives = 202/482 (41%), Gaps = 31/482 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K A D + +++ + +++ E +HN + S E + +
Sbjct: 345 KEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQM 404
Query: 109 KRENIQMHT---SDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISI 165
+ + Q+ +++ + + L + ++ TN ES + L N + +D +
Sbjct: 405 QMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAEL------NKLRQDYARL 458
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNC----IQEE 221
L + K + + + +N+ + +K + A E+ +E++ + + K+ Q++
Sbjct: 459 VNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEA-ERRWEEVQSYIRKRTAEHEAAQQD 517
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE---KLSEIKEK 278
+ + +N +Q R + E+ + E ++ +I E+
Sbjct: 518 LQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQ 577
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+E K +I + + I + + +E + ++++ K++ +TE L ++++LT E+
Sbjct: 578 NEALKAQIQQFHSQ-IAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 636
Query: 339 LNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY---ERISLTLDKITNH 395
L D +N ++ L++ K+ +A++ + EL+ ++ Y ++I L +++ +
Sbjct: 637 LKDIQNMNF-LLKAEVQKLQALANE---QAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 692
Query: 396 ITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRG 455
I+ + + + N L E +K ++EQ K+ + Q+E +E +++TV
Sbjct: 693 ISNKMEEF-KILNDQNKALKSEVQKLQTLVSEQP--NKDVVEQMEKCIQEKDEKLKTVEE 749
Query: 456 SNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK---VMEWKSQFEDLDDVMKQQQKE 512
E + + + E++D+K K + + S E+L V+ ++ +
Sbjct: 750 LLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGK 809
Query: 513 LK 514
+K
Sbjct: 810 IK 811
Score = 43.6 bits (98), Expect = 0.002
Identities = 76/335 (22%), Positives = 148/335 (44%), Gaps = 46/335 (13%)
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD----KFIANLEEMKTM 266
A ++ +E +L I+N N L A + + +++ K
Sbjct: 624 ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIR 683
Query: 267 LVEEKLS-EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK--VNKTER 323
L+EE+L EI K E FK +LN++ + +Q+ L+S+ K V + E+
Sbjct: 684 LLEEQLQHEISNKMEEFK----ILNDQ----NKALKSEVQKLQTLVSEQPNKDVVEQMEK 735
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
++EK E+L +E+L +T LI+ + K ++ + ++ L+ E+ D +
Sbjct: 736 CIQEKDEKLK-TVEELLETG-----LIQ-VATKEEELNAIRTENSSLTKEVQDLKAKQND 788
Query: 384 RISLT--LDKITNHITYLNTQINETQKNDNAQLLWEAKKQ--IADLTEQNIILKERLSQL 439
++S ++++ I + +I ++ A+LL A K+ + DL ++ LKE + +
Sbjct: 789 QVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNV 848
Query: 440 ETENKELLI------EIQTV-RGSNEEV-TLN--LKDSSTXXXXXXXXXXXXSNEIEDMK 489
+ E + L E+Q + +G E++ T+ L++ E E +K
Sbjct: 849 QLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Query: 490 TKVMEWK----------SQFEDLDDVMKQQQKELK 514
V E SQFE+L+ V+K+++ ELK
Sbjct: 909 AHVQEVAQHNLKEASSASQFEELEIVLKEKENELK 943
Score = 34.7 bits (76), Expect = 0.80
Identities = 80/399 (20%), Positives = 168/399 (42%), Gaps = 33/399 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNG- 140
EK+ + +D +L E+ + K E ++ + + L +++ N
Sbjct: 669 EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKD 728
Query: 141 -FESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR--NS--IKYLESVKS 195
E +E+ E D K ++ + ++T L ++ TK E ++N +R NS K ++ +K+
Sbjct: 729 VVEQMEKCIQEKDEKLKTVEE---LLETGLIQVATKEE-ELNAIRTENSSLTKEVQDLKA 784
Query: 196 EYN--TANEKLFEQLNNAV-DKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
+ N + L E+L + +K I+ +LL+ E LL+
Sbjct: 785 KQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE---LLKVANKEKTVQDLKQEIKAL 841
Query: 253 RDKF-IANLEEMKTMLVEEKLSEI------KEKDENFKQEIDMLNEKLICDRREFNETMQ 305
+++ LE+ + + + K+ E+ KE+ N + + EK + + ++ + +Q
Sbjct: 842 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
E+N L ++V + + Q L L + E N K +E M + + SD
Sbjct: 902 EENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKE-NELKRLEAM---LKERESDLS 957
Query: 366 ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL 425
QL ++ DE++ +I K N+ + +E + +++ E +K+I+ L
Sbjct: 958 SKTQLLQDVQDENKLFKSQIEQL--KQQNYQQASSFPPHE----ELLKVISEREKEISGL 1011
Query: 426 TEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNL 464
+ LK+ + +N E +++ V +EV L
Sbjct: 1012 WNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKL 1050
>EF179180-1|ABN05283.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 50.4 bits (115), Expect = 1e-05
Identities = 95/492 (19%), Positives = 197/492 (40%), Gaps = 44/492 (8%)
Query: 41 QQNVGVGDKTVAEL-KND-EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLY 98
Q N+ ++ +L KN ++ + ++++ LT K E + ++LK+
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 99 EDSASELEALKREN------IQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+D L +++E ++ T ++ + EII LT+ L + +L+++ E
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
D K N++TK + K E +++L S++ + V+ + A KL L
Sbjct: 1015 D-KVNTLTKAKV-----------KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-- 1060
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +++ + E D +++ + L + + L+E++ + E+
Sbjct: 1061 LTQESIMDLENDKQQLD-ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARI--EE 1117
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS---DLSKK----VNKTERE 324
L E E + + +++ L L + E +E ++E S +++KK K R+
Sbjct: 1118 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 1177
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYE 383
LEE Q L +S + + + ++ K ++ ELDD + N E
Sbjct: 1178 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-ME 1236
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL--ET 441
+I + L Q+NE + E ++ + DLT Q L+ +L +
Sbjct: 1237 QIIKAKANLEKMCRTLEDQMNEHRSKAE-----ETQRSVNDLTSQRAKLQTENGELSRQL 1291
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ KE LI Q RG T L+D ++ ++ + + Q+E+
Sbjct: 1292 DEKEALIS-QLTRG-KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349
Query: 502 LDDVMKQQQKEL 513
+ + Q+ L
Sbjct: 1350 ETEAKAELQRVL 1361
Score = 40.7 bits (91), Expect = 0.012
Identities = 50/260 (19%), Positives = 108/260 (41%), Gaps = 30/260 (11%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDL 314
ANLE+M L E++++E + K E ++ ++ L KL + E + + EK L+S L
Sbjct: 1243 ANLEKMCRTL-EDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL 1301
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++ ++LE+ + QL E+ +N +++ + + ++ + EL
Sbjct: 1302 TRGKLTYTQQLEDLKRQL----EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 1357
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+R+ L K + + T+ ET + L EAKK++A +
Sbjct: 1358 --------QRV---LSKANSEVAQWRTKY-ETDAIQRTEELEEAKKKLA----------Q 1395
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
RL + E + + + ++ + + ++D + + + E
Sbjct: 1396 RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1455
Query: 495 WKSQFEDLDDVMKQQQKELK 514
WK ++E+ ++ QKE +
Sbjct: 1456 WKQKYEESQSELESSQKEAR 1475
Score = 39.9 bits (89), Expect = 0.021
Identities = 60/311 (19%), Positives = 122/311 (39%), Gaps = 23/311 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLD-KLITKNETDINELRNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK ++ KL K+E RN ++ ++S+++ +
Sbjct: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E L + + E L N+ + D +
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 260 LEEMK--TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K +VE + + ++ + E + ++ +E ET + +L S +
Sbjct: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723
Query: 318 VN---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+N K + +L + Q ++ +++ + E + K I + + +A + K S L
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD----AAMMAEELKKEQDTSAHL 1779
Query: 375 DDESENTYERI 385
+ +N + I
Sbjct: 1780 ERMKKNMEQTI 1790
Score = 36.7 bits (81), Expect = 0.20
Identities = 92/409 (22%), Positives = 163/409 (39%), Gaps = 43/409 (10%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q ++ V + + L+ + + + I L L +K
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF-E 142
+ + K+ YE+S SELE+ ++E SL+ + L N + E
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKE---------------ARSLSTELFKLKNAYEE 1490
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
SLE LE ++N ++ IS L ++L + +T I+EL K LE+ K E +A E
Sbjct: 1491 SLEH--LETFKRENKNLQEEIS--DLTEQLGSSGKT-IHELEKVRKQLEAEKMELQSALE 1545
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ L + K Q E + +K E + L A+ + ++
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKL---------AEKDEEMEQAKRNHLRVVDS 1596
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
++T L E S + K E D LNE I N E + L + T+
Sbjct: 1597 LQTSLDAETRSRNEALRVKKKMEGD-LNEMEI-QLSHANRMAAEAQKQVKSLQSLLKDTQ 1654
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKL---IENMFNKVSQIASDFKISNQLSCELDDESE 379
+L++ L E + E + L +E + V Q K++ Q E + +
Sbjct: 1655 IQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ 1714
Query: 380 NTYERISLTLD---KITNHITYLNTQINE-TQKNDNAQLLWEAKKQIAD 424
+ + + ++ K+ ++ L T++ E Q+ NA+ +AKK I D
Sbjct: 1715 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE--EKAKKAITD 1761
Score = 35.5 bits (78), Expect = 0.46
Identities = 38/222 (17%), Positives = 98/222 (44%), Gaps = 6/222 (2%)
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+R + +M+E+ L + +K +ELEEK + L+++ ND + +N+ +
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEK---MVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQL 414
+ K QL ++ + +E + + + +T L + +E +++ D+ +L
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKRDIDDLEL 959
Query: 415 LWEAKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1061
>D13629-1|BAA02794.2| 1307|Homo sapiens KIAA0004 protein.
Length = 1307
Score = 50.4 bits (115), Expect = 1e-05
Identities = 79/482 (16%), Positives = 202/482 (41%), Gaps = 31/482 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K A D + +++ + +++ E +HN + S E + +
Sbjct: 352 KEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQM 411
Query: 109 KRENIQMHT---SDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISI 165
+ + Q+ +++ + + L + ++ TN ES + L N + +D +
Sbjct: 412 QMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAEL------NKLRQDYARL 465
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNC----IQEE 221
L + K + + + +N+ + +K + A E+ +E++ + + K+ Q++
Sbjct: 466 VNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEA-ERRWEEVQSYIRKRTAEHEAAQQD 524
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE---KLSEIKEK 278
+ + +N +Q R + E+ + E ++ +I E+
Sbjct: 525 LQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQ 584
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+E K +I + + I + + +E + ++++ K++ +TE L ++++LT E+
Sbjct: 585 NEALKAQIQQFHSQ-IAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 643
Query: 339 LNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY---ERISLTLDKITNH 395
L D +N ++ L++ K+ +A++ + EL+ ++ Y ++I L +++ +
Sbjct: 644 LKDIQNMNF-LLKAEVQKLQALANE---QAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 699
Query: 396 ITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRG 455
I+ + + + N L E +K ++EQ K+ + Q+E +E +++TV
Sbjct: 700 ISNKMEEF-KILNDQNKALKSEVQKLQTLVSEQP--NKDVVEQMEKCIQEKDEKLKTVEE 756
Query: 456 SNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK---VMEWKSQFEDLDDVMKQQQKE 512
E + + + E++D+K K + + S E+L V+ ++ +
Sbjct: 757 LLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGK 816
Query: 513 LK 514
+K
Sbjct: 817 IK 818
Score = 43.6 bits (98), Expect = 0.002
Identities = 76/335 (22%), Positives = 148/335 (44%), Gaps = 46/335 (13%)
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD----KFIANLEEMKTM 266
A ++ +E +L I+N N L A + + +++ K
Sbjct: 631 ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIR 690
Query: 267 LVEEKLS-EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK--VNKTER 323
L+EE+L EI K E FK +LN++ + +Q+ L+S+ K V + E+
Sbjct: 691 LLEEQLQHEISNKMEEFK----ILNDQ----NKALKSEVQKLQTLVSEQPNKDVVEQMEK 742
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
++EK E+L +E+L +T LI+ + K ++ + ++ L+ E+ D +
Sbjct: 743 CIQEKDEKLK-TVEELLETG-----LIQ-VATKEEELNAIRTENSSLTKEVQDLKAKQND 795
Query: 384 RISLT--LDKITNHITYLNTQINETQKNDNAQLLWEAKKQ--IADLTEQNIILKERLSQL 439
++S ++++ I + +I ++ A+LL A K+ + DL ++ LKE + +
Sbjct: 796 QVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNV 855
Query: 440 ETENKELLI------EIQTV-RGSNEEV-TLN--LKDSSTXXXXXXXXXXXXSNEIEDMK 489
+ E + L E+Q + +G E++ T+ L++ E E +K
Sbjct: 856 QLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 915
Query: 490 TKVMEWK----------SQFEDLDDVMKQQQKELK 514
V E SQFE+L+ V+K+++ ELK
Sbjct: 916 AHVQEVAQHNLKEASSASQFEELEIVLKEKENELK 950
Score = 34.7 bits (76), Expect = 0.80
Identities = 80/399 (20%), Positives = 168/399 (42%), Gaps = 33/399 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNG- 140
EK+ + +D +L E+ + K E ++ + + L +++ N
Sbjct: 676 EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKD 735
Query: 141 -FESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR--NS--IKYLESVKS 195
E +E+ E D K ++ + ++T L ++ TK E ++N +R NS K ++ +K+
Sbjct: 736 VVEQMEKCIQEKDEKLKTVEE---LLETGLIQVATKEE-ELNAIRTENSSLTKEVQDLKA 791
Query: 196 EYN--TANEKLFEQLNNAV-DKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
+ N + L E+L + +K I+ +LL+ E LL+
Sbjct: 792 KQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE---LLKVANKEKTVQDLKQEIKAL 848
Query: 253 RDKF-IANLEEMKTMLVEEKLSEI------KEKDENFKQEIDMLNEKLICDRREFNETMQ 305
+++ LE+ + + + K+ E+ KE+ N + + EK + + ++ + +Q
Sbjct: 849 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 908
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
E+N L ++V + + Q L L + E N K +E M + + SD
Sbjct: 909 EENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKE-NELKRLEAM---LKERESDLS 964
Query: 366 ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL 425
QL ++ DE++ +I K N+ + +E + +++ E +K+I+ L
Sbjct: 965 SKTQLLQDVQDENKLFKSQIEQL--KQQNYQQASSFPPHE----ELLKVISEREKEISGL 1018
Query: 426 TEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNL 464
+ LK+ + +N E +++ V +EV L
Sbjct: 1019 WNELDSLKDAVEHQRKKNNERQQQVEAVELEAKEVLKKL 1057
>BC117174-1|AAI17175.1| 1291|Homo sapiens KIF15 protein protein.
Length = 1291
Score = 50.4 bits (115), Expect = 1e-05
Identities = 69/360 (19%), Positives = 154/360 (42%), Gaps = 30/360 (8%)
Query: 169 LDKLITKNE---TDINELR----NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEE 221
L + TKN+ +++++LR ++ K L SVK EY++ ++ N ++ +Q +
Sbjct: 689 LQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQ 748
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE---KLSEIKEK 278
+D L++EN+ LL+ +D + NL+E+ +++ L K++
Sbjct: 749 LDNLRLENEKLLE-------------SKACLQDSY-DNLQEIMKFEIDQLSRNLQNFKKE 794
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT-ERELEEKQEQLTHLME 337
+E K +++ L E L ++ N+ + + SK++ K E +EKQ++ +
Sbjct: 795 NETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQ 854
Query: 338 QLNDTENNSYKLI--ENMFNKVSQIA-SDFKISNQLSCELDDESENTYERISLTLDKITN 394
Q+ + L+ E + + + + SD K+ L ++ + + E+ T+D +
Sbjct: 855 QMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRSSVCEKTE-TIDTLKQ 913
Query: 395 HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVR 454
+ +N + N D + KKQ D+ + L+ R+ + E L ++
Sbjct: 914 ELKDINCKYNSALV-DREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHAT 972
Query: 455 GSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+T K S I++++ K+ + K + E + + ++L+
Sbjct: 973 EQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLE 1032
Score = 35.9 bits (79), Expect = 0.34
Identities = 79/434 (18%), Positives = 169/434 (38%), Gaps = 29/434 (6%)
Query: 25 RLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKL 84
+LEE ++ S L+++ K VA+L N I++L L ++L
Sbjct: 861 KLEESLLATEKVISSLEKSRDSDKKVVADLMNQ-----IQELRSSVCEKTETIDTLKQEL 915
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQM-HTSDVMVVPEIIDSLTEVINTLTNGFES 143
K+N E+S ++ + + + + T + ++ E I+ + L + E
Sbjct: 916 KDINCKYNSALVDREESRVLIKKQEVDILDLKETLRLRILSEDIER-DMLCEDLAHATEQ 974
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
L + E K + + + T + LI + + +N+ + + E K+EYN +
Sbjct: 975 LNMLT-EASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEV---EQKKNEYNFKMRQ 1030
Query: 204 LFEQLNNAVDKQNCIQEE-------VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
L +++A + + LL+ + Q + R+
Sbjct: 1031 LEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVK 1090
Query: 257 IANLEEMKTMLVE-EKL----SEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
A + MK L E E L ++ EK+ + ++D + + + + Q KN
Sbjct: 1091 NAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQE 1150
Query: 312 SDLSKKVNKTE--RELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
+ +++ K++ E+ + + L + L + E ++ + + + + F+ Q
Sbjct: 1151 ESIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQ 1210
Query: 370 LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQN 429
L +L++ E ER S ++ + + L E K Q L + + + L ++N
Sbjct: 1211 LRSKLEEMYEER-ERTSQEMEMLRKQVECL---AEENGKLVGHQNLHQKIQYVVRLKKEN 1266
Query: 430 IILKERLSQLETEN 443
+ L E +L EN
Sbjct: 1267 VRLAEETEKLRAEN 1280
Score = 35.1 bits (77), Expect = 0.60
Identities = 63/347 (18%), Positives = 145/347 (41%), Gaps = 27/347 (7%)
Query: 12 NENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXX 71
N+ +++ +H ++ L KE+ +K L+ + KT E + ++++ +
Sbjct: 696 NDFLKSEVHDLRVVLHSADKELSSVK--LEYS---SFKTNQEKEFNKLSERHMHVQLQLD 750
Query: 72 XXXXXXXXLTEKLTIAETKHNDLKKLYE---DSASE-LEALKRENIQMHTSDVMVVPEII 127
L E + +++L+++ + D S L+ K+EN + SD+ + E++
Sbjct: 751 NLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLK-SDLNNLMELL 809
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTL-LDKLITKNETDINELRNS 186
++ E N L+ FE +E + + LK + +T ++ + K + L +
Sbjct: 810 EAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLAT 869
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
K + S++ ++ + + + +N + ++ + E+ + + Q L
Sbjct: 870 EKVISSLEKSRDSDKKVVADLMNQIQELRSSVCEKTETIDTLKQELKDINCKYNSALVDR 929
Query: 247 XXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD---ENFKQEIDMLNEKLICDRREFN-- 301
K ++ ++K L LSE E+D E+ + LN ++
Sbjct: 930 EESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLL 989
Query: 302 ----ETMQEKNILLSDLSKKVNKTERELEEKQE-------QLTHLME 337
E + +K L+ +L K+N+ + E+E+K+ QL H+M+
Sbjct: 990 QSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMD 1036
Score = 31.1 bits (67), Expect = 9.8
Identities = 69/378 (18%), Positives = 145/378 (38%), Gaps = 15/378 (3%)
Query: 90 KHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVAL 149
+H D + + EL + +R + +++ +++ + T N F E L
Sbjct: 648 QHVDKLEHHSTQMQELFSSERIDWTKQQEELLSQLNVLEKQLQETQT-KNDFLKSEVHDL 706
Query: 150 EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ-- 207
+ L +S K+ S+K T E + N+L +++ NEKL E
Sbjct: 707 RVVL--HSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQLDNLRLENEKLLESKA 764
Query: 208 -LNNAVDK-QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKT 265
L ++ D Q ++ E+D L QN + A + L
Sbjct: 765 CLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKLSLQFE 824
Query: 266 MLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
E EI + E +QE E C+++ E+++L ++ K ++ E+
Sbjct: 825 EDKENSSKEILKVLEAVRQE--KQKETAKCEQQMAKVQKLEESLLATE--KVISSLEKSR 880
Query: 326 EEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI 385
+ ++ + LM Q+ + ++ + E + + + Q D + +ES ++
Sbjct: 881 DSDKKVVADLMNQIQELRSSVCEKTETI-DTLKQELKDINCKYNSALVDREESRVLIKKQ 939
Query: 386 SL-TLD-KITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETEN 443
+ LD K T + L+ I ++ E + + ++++ L + + T+
Sbjct: 940 EVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKK 999
Query: 444 KELLIEIQ-TVRGSNEEV 460
+ L+ E+Q + EEV
Sbjct: 1000 EALIQELQHKLNQKKEEV 1017
>BC112173-1|AAI12174.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 50.4 bits (115), Expect = 1e-05
Identities = 95/492 (19%), Positives = 197/492 (40%), Gaps = 44/492 (8%)
Query: 41 QQNVGVGDKTVAEL-KND-EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLY 98
Q N+ ++ +L KN ++ + ++++ LT K E + ++LK+
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 99 EDSASELEALKREN------IQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+D L +++E ++ T ++ + EII LT+ L + +L+++ E
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
D K N++TK + K E +++L S++ + V+ + A KL L
Sbjct: 1015 D-KVNTLTKAKV-----------KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-- 1060
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +++ + E D +++ + L + + L+E++ + E+
Sbjct: 1061 LTQESIMDLENDKQQLD-ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARI--EE 1117
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS---DLSKK----VNKTERE 324
L E E + + +++ L L + E +E ++E S +++KK K R+
Sbjct: 1118 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 1177
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYE 383
LEE Q L +S + + + ++ K ++ ELDD + N E
Sbjct: 1178 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-ME 1236
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL--ET 441
+I + L Q+NE + E ++ + DLT Q L+ +L +
Sbjct: 1237 QIIKAKANLEKMCRTLEDQMNEHRSKAE-----ETQRSVNDLTSQRAKLQTENGELSRQL 1291
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ KE LI Q RG T L+D ++ ++ + + Q+E+
Sbjct: 1292 DEKEALIS-QLTRG-KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349
Query: 502 LDDVMKQQQKEL 513
+ + Q+ L
Sbjct: 1350 ETEAKAELQRVL 1361
Score = 40.7 bits (91), Expect = 0.012
Identities = 50/260 (19%), Positives = 108/260 (41%), Gaps = 30/260 (11%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDL 314
ANLE+M L E++++E + K E ++ ++ L KL + E + + EK L+S L
Sbjct: 1243 ANLEKMCRTL-EDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL 1301
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++ ++LE+ + QL E+ +N +++ + + ++ + EL
Sbjct: 1302 TRGKLTYTQQLEDLKRQL----EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 1357
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+R+ L K + + T+ ET + L EAKK++A +
Sbjct: 1358 --------QRV---LSKANSEVAQWRTKY-ETDAIQRTEELEEAKKKLA----------Q 1395
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
RL + E + + + ++ + + ++D + + + E
Sbjct: 1396 RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1455
Query: 495 WKSQFEDLDDVMKQQQKELK 514
WK ++E+ ++ QKE +
Sbjct: 1456 WKQKYEESQSELESSQKEAR 1475
Score = 39.9 bits (89), Expect = 0.021
Identities = 60/311 (19%), Positives = 122/311 (39%), Gaps = 23/311 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLD-KLITKNETDINELRNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK ++ KL K+E RN ++ ++S+++ +
Sbjct: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E L + + E L N+ + D +
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 260 LEEMK--TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K +VE + + ++ + E + ++ +E ET + +L S +
Sbjct: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723
Query: 318 VN---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+N K + +L + Q ++ +++ + E + K I + + +A + K S L
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD----AAMMAEELKKEQDTSAHL 1779
Query: 375 DDESENTYERI 385
+ +N + I
Sbjct: 1780 ERMKKNMEQTI 1790
Score = 36.7 bits (81), Expect = 0.20
Identities = 92/409 (22%), Positives = 163/409 (39%), Gaps = 43/409 (10%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q ++ V + + L+ + + + I L L +K
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF-E 142
+ + K+ YE+S SELE+ ++E SL+ + L N + E
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKE---------------ARSLSTELFKLKNAYEE 1490
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
SLE LE ++N ++ IS L ++L + +T I+EL K LE+ K E +A E
Sbjct: 1491 SLEH--LETFKRENKNLQEEIS--DLTEQLGSSGKT-IHELEKVRKQLEAEKMELQSALE 1545
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ L + K Q E + +K E + L A+ + ++
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKL---------AEKDEEMEQAKRNHLRVVDS 1596
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
++T L E S + K E D LNE I N E + L + T+
Sbjct: 1597 LQTSLDAETRSRNEALRVKKKMEGD-LNEMEI-QLSHANRMAAEAQKQVKSLQSLLKDTQ 1654
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKL---IENMFNKVSQIASDFKISNQLSCELDDESE 379
+L++ L E + E + L +E + V Q K++ Q E + +
Sbjct: 1655 IQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ 1714
Query: 380 NTYERISLTLD---KITNHITYLNTQINE-TQKNDNAQLLWEAKKQIAD 424
+ + + ++ K+ ++ L T++ E Q+ NA+ +AKK I D
Sbjct: 1715 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE--EKAKKAITD 1761
Score = 35.5 bits (78), Expect = 0.46
Identities = 38/222 (17%), Positives = 98/222 (44%), Gaps = 6/222 (2%)
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+R + +M+E+ L + +K +ELEEK + L+++ ND + +N+ +
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEK---MVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQL 414
+ K QL ++ + +E + + + +T L + +E +++ D+ +L
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKRDIDDLEL 959
Query: 415 LWEAKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1061
>BC112171-1|AAI12172.1| 1935|Homo sapiens myosin, heavy chain 7,
cardiac muscle, beta protein.
Length = 1935
Score = 50.4 bits (115), Expect = 1e-05
Identities = 95/492 (19%), Positives = 197/492 (40%), Gaps = 44/492 (8%)
Query: 41 QQNVGVGDKTVAEL-KND-EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLY 98
Q N+ ++ +L KN ++ + ++++ LT K E + ++LK+
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 99 EDSASELEALKREN------IQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+D L +++E ++ T ++ + EII LT+ L + +L+++ E
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
D K N++TK + K E +++L S++ + V+ + A KL L
Sbjct: 1015 D-KVNTLTKAKV-----------KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-- 1060
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +++ + E D +++ + L + + L+E++ + E+
Sbjct: 1061 LTQESIMDLENDKQQLD-ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARI--EE 1117
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS---DLSKK----VNKTERE 324
L E E + + +++ L L + E +E ++E S +++KK K R+
Sbjct: 1118 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 1177
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYE 383
LEE Q L +S + + + ++ K ++ ELDD + N E
Sbjct: 1178 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-ME 1236
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL--ET 441
+I + L Q+NE + E ++ + DLT Q L+ +L +
Sbjct: 1237 QIIKAKANLEKMCRTLEDQMNEHRSKAE-----ETQRSVNDLTSQRAKLQTENGELSRQL 1291
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ KE LI Q RG T L+D ++ ++ + + Q+E+
Sbjct: 1292 DEKEALIS-QLTRG-KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349
Query: 502 LDDVMKQQQKEL 513
+ + Q+ L
Sbjct: 1350 ETEAKAELQRVL 1361
Score = 40.7 bits (91), Expect = 0.012
Identities = 50/260 (19%), Positives = 108/260 (41%), Gaps = 30/260 (11%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDL 314
ANLE+M L E++++E + K E ++ ++ L KL + E + + EK L+S L
Sbjct: 1243 ANLEKMCRTL-EDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL 1301
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++ ++LE+ + QL E+ +N +++ + + ++ + EL
Sbjct: 1302 TRGKLTYTQQLEDLKRQL----EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 1357
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+R+ L K + + T+ ET + L EAKK++A +
Sbjct: 1358 --------QRV---LSKANSEVAQWRTKY-ETDAIQRTEELEEAKKKLA----------Q 1395
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
RL + E + + + ++ + + ++D + + + E
Sbjct: 1396 RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1455
Query: 495 WKSQFEDLDDVMKQQQKELK 514
WK ++E+ ++ QKE +
Sbjct: 1456 WKQKYEESQSELESSQKEAR 1475
Score = 39.9 bits (89), Expect = 0.021
Identities = 60/311 (19%), Positives = 122/311 (39%), Gaps = 23/311 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLD-KLITKNETDINELRNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK ++ KL K+E RN ++ ++S+++ +
Sbjct: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E L + + E L N+ + D +
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 260 LEEMK--TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K +VE + + ++ + E + ++ +E ET + +L S +
Sbjct: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723
Query: 318 VN---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+N K + +L + Q ++ +++ + E + K I + + +A + K S L
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD----AAMMAEELKKEQDTSAHL 1779
Query: 375 DDESENTYERI 385
+ +N + I
Sbjct: 1780 ERMKKNMEQTI 1790
Score = 36.7 bits (81), Expect = 0.20
Identities = 92/409 (22%), Positives = 163/409 (39%), Gaps = 43/409 (10%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q ++ V + + L+ + + + I L L +K
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF-E 142
+ + K+ YE+S SELE+ ++E SL+ + L N + E
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKE---------------ARSLSTELFKLKNAYEE 1490
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
SLE LE ++N ++ IS L ++L + +T I+EL K LE+ K E +A E
Sbjct: 1491 SLEH--LETFKRENKNLQEEIS--DLTEQLGSSGKT-IHELEKVRKQLEAEKMELQSALE 1545
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ L + K Q E + +K E + L A+ + ++
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKL---------AEKDEEMEQAKRNHLRVVDS 1596
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
++T L E S + K E D LNE I N E + L + T+
Sbjct: 1597 LQTSLDAETRSRNEALRVKKKMEGD-LNEMEI-QLSHANRMAAEAQKQVKSLQSLLKDTQ 1654
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKL---IENMFNKVSQIASDFKISNQLSCELDDESE 379
+L++ L E + E + L +E + V Q K++ Q E + +
Sbjct: 1655 IQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ 1714
Query: 380 NTYERISLTLD---KITNHITYLNTQINE-TQKNDNAQLLWEAKKQIAD 424
+ + + ++ K+ ++ L T++ E Q+ NA+ +AKK I D
Sbjct: 1715 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE--EKAKKAITD 1761
Score = 35.5 bits (78), Expect = 0.46
Identities = 38/222 (17%), Positives = 98/222 (44%), Gaps = 6/222 (2%)
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+R + +M+E+ L + +K +ELEEK + L+++ ND + +N+ +
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEK---MVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQL 414
+ K QL ++ + +E + + + +T L + +E +++ D+ +L
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKRDIDDLEL 959
Query: 415 LWEAKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1061
>BC078168-1|AAH78168.1| 887|Homo sapiens KIAA1212 protein protein.
Length = 887
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
E+ Q ++ L+D K+ + +ELEEK EQL ++L E +L + N +S
Sbjct: 241 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 300
Query: 362 SDFKISNQLSC--ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
S ++L E + +S +++ + I + ++ E K DN Q+L E K
Sbjct: 301 SARMYRDELDALREKAVRVDKLESEVSRYKERL-HDIEFYKARVEEL-KEDN-QVLLETK 357
Query: 420 KQIADLTEQNIILKERLSQLETENKEL 446
+ D E ++L +LE EN +L
Sbjct: 358 TMLEDQLEGTRARSDKLHELEKENLQL 384
Score = 46.4 bits (105), Expect = 2e-04
Identities = 75/411 (18%), Positives = 172/411 (41%), Gaps = 26/411 (6%)
Query: 99 EDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSI 158
E +AS++ +++EN ++ ++ EI+ + N + ++E A L+K
Sbjct: 484 EGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKA---QLEKTIE 540
Query: 159 TKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTA-----NEKLFEQLNNAVD 213
T S + + K++ + +N+ +S++ + +E N+ L E +
Sbjct: 541 TLRENSERQI--KILEQENEHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSS 598
Query: 214 KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLS 273
K + I+ E +K E ++ + + + +K + EK+
Sbjct: 599 KLSKIEFEKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLK--ITCEKIE 656
Query: 274 EIKEKDENFKQEIDMLNEKLICDRR-EFN-ETMQEKNILLSDLSKKVNKTERELEEKQEQ 331
+++++ ++E L + L + F E+++++N L + + ++ + L+ +
Sbjct: 657 ALEQENSELERENRKLKKTLDSFKNLTFQLESLEKENSQLDEENLELRRNVESLKCASMK 716
Query: 332 LTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD-ESENTYERISLTLD 390
+ L QL + E S K E + + + + FK + +L + EN +R+ TL+
Sbjct: 717 MAQL--QLENKELESEK--EQLKKGLELLKASFKKTERLEVSYQGLDIEN--QRLQKTLE 770
Query: 391 KITNHITYLNTQINETQKND-----NAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
I L +++ + + + N + L + K++ L ++N L++ SQLE + K+
Sbjct: 771 NSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQETSQLEKDKKQ 830
Query: 446 LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWK 496
L E + +R E L++++ S EI K + K
Sbjct: 831 LEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTLSKEIGIYKESCVRLK 881
Score = 35.1 bits (77), Expect = 0.60
Identities = 83/452 (18%), Positives = 176/452 (38%), Gaps = 30/452 (6%)
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
+ + + D++ L ++ A L+ L E + H+ ++ + E D L + + ++
Sbjct: 173 MEVTDMSQEDIEPLLKNMALHLKRLIDERDE-HSETIIELSEERDGLHFLPHASSSAQSP 231
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
++ + ++ + K + +L + E +L + + LE ++ E ++
Sbjct: 232 CGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE 291
Query: 204 LFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN-- 259
L++A + ++E+D L K + L+ AR + +
Sbjct: 292 NMNLLSDARSAR-MYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDN 350
Query: 260 --LEEMKTMLVEE---------KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
L E KTML ++ KL E+++++ K ++ + + DR++ E M+E N
Sbjct: 351 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE-N 409
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN 368
+ L K+ L + EQ++ E L++ S L + S ++ N
Sbjct: 410 MTLEMAQKQSMDESLHLGWELEQISRTSE-LSEAPQKS--LGHEVNELTSSRLLKLEMEN 466
Query: 369 QLSCELDDESENTYERISLTLDKI-----TNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
Q + +E T + + KI N +I E + Q L +
Sbjct: 467 QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 526
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL-NLKDSSTXXXXXXXXXXXXS 482
DL ++ L++ + L EN E I+I + T+ +L+ S
Sbjct: 527 DLMKEKAQLEKTIETLR-ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE 585
Query: 483 NEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
N+I + + E S+ ++ +Q +KEL+
Sbjct: 586 NKI--LHESIKETSSKLSKIEFEKRQIKKELE 615
>BC050555-1|AAH50555.1| 873|Homo sapiens KTN1 protein protein.
Length = 873
Score = 50.4 bits (115), Expect = 1e-05
Identities = 79/482 (16%), Positives = 202/482 (41%), Gaps = 31/482 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K A D + +++ + +++ E +HN + S E + +
Sbjct: 345 KEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQM 404
Query: 109 KRENIQMHT---SDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISI 165
+ + Q+ +++ + + L + ++ TN ES + L N + +D +
Sbjct: 405 QMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAEL------NKLRQDYARL 458
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNC----IQEE 221
L + K + + + +N+ + +K + A E+ +E++ + + K+ Q++
Sbjct: 459 VNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEA-ERRWEEVQSYIRKRTAEHEAAQQD 517
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE---KLSEIKEK 278
+ + +N +Q R + E+ + E ++ +I E+
Sbjct: 518 LQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQ 577
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+E K +I + + I + + +E + ++++ K++ +TE L ++++LT E+
Sbjct: 578 NEALKAQIQQFHSQ-IAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 636
Query: 339 LNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY---ERISLTLDKITNH 395
L D +N ++ L++ K+ +A++ + EL+ ++ Y ++I L +++ +
Sbjct: 637 LKDIQNMNF-LLKAEVQKLQALANE---QAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 692
Query: 396 ITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRG 455
I+ + + + N L E +K ++EQ K+ + Q+E +E +++TV
Sbjct: 693 ISNKMEEF-KILNDQNKALKSEVQKLQTLVSEQP--NKDVVEQMEKCIQEKDEKLKTVEE 749
Query: 456 SNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK---VMEWKSQFEDLDDVMKQQQKE 512
E + + + E++D+K K + + S E+L V+ ++ +
Sbjct: 750 LLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGK 809
Query: 513 LK 514
+K
Sbjct: 810 IK 811
Score = 39.9 bits (89), Expect = 0.021
Identities = 54/298 (18%), Positives = 117/298 (39%), Gaps = 18/298 (6%)
Query: 55 KNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQ 114
+N+ + + I+Q E + K +K+ + ASE + L + +
Sbjct: 577 QNEALKAQIQQFHSQIAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 636
Query: 115 MHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLIT 174
+ D+ + ++ + + + L N A E++ + S+ + I+ L ++L
Sbjct: 637 L--KDIQNMNFLLKAEVQKLQALAN---EQAAAAHELEKMQQSVYVKDDKIRLLEEQLQH 691
Query: 175 KNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQ--NCIQEEVDLLKIENQNL 232
+ + E + +++KSE + EQ N V +Q CIQE+ + LK + L
Sbjct: 692 EISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEELL 751
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTM---------LVEEKLSEIKEKDENFK 283
++++K LVEE I EKD K
Sbjct: 752 ETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGKIK 811
Query: 284 QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLND 341
++L +L+ + +T+Q+ + L +++ + E + +Q +T +++L +
Sbjct: 812 SVEELLEAELLKVANK-EKTVQDLKQEIKALKEEIGNVQLE-KAQQLSITSKVQELQN 867
>BC041160-1|AAH41160.1| 501|Homo sapiens KIAA1212 protein protein.
Length = 501
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
E+ Q ++ L+D K+ + +ELEEK EQL ++L E +L + N +S
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 303
Query: 362 SDFKISNQLSC--ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
S ++L E + +S +++ + I + ++ E K DN Q+L E K
Sbjct: 304 SARMYRDELDALREKAVRVDKLESEVSRYKERL-HDIEFYKARVEEL-KEDN-QVLLETK 360
Query: 420 KQIADLTEQNIILKERLSQLETENKEL 446
+ D E ++L +LE EN +L
Sbjct: 361 TMLEDQLEGTRARSDKLHELEKENLQL 387
>BC028423-1|AAH28423.1| 1022|Homo sapiens PMFBP1 protein protein.
Length = 1022
Score = 50.4 bits (115), Expect = 1e-05
Identities = 74/329 (22%), Positives = 137/329 (41%), Gaps = 19/329 (5%)
Query: 150 EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLN 209
E++ + K + ++K KL +NE EL+ LES ++YNT ++++ + LN
Sbjct: 641 ELEALRQEFKKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNKYNT-SQQVIQDLN 699
Query: 210 N--AVDKQN--CIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM-- 263
A+ K++ +Q ++D + ++ LQ +D LE++
Sbjct: 700 KEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQDDLTQALEKLNH 759
Query: 264 ---KTMLVEEKLSEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDLSKK 317
+T +++ L++ +EK ++EI E KL + R+ QE + + KK
Sbjct: 760 VTSETKSLQQSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKLRGFHQESELEVHAFDKK 819
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE 377
+ + ++ + Q+Q + ++ L E + E M + D K + C
Sbjct: 820 LEEMSCQVLQWQKQHQNDLKMLAAKEEQLREFQEEMAALKENLLEDDK---EPCCLPQWS 876
Query: 378 SENTYERISLTLDKI-TNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERL 436
R+ D+I TN + Q +K N L E K IA L+ + L +
Sbjct: 877 VPKDTCRLYRGNDQIMTNLEQWAKQQKVANEKLGNQ--LREQVKYIAKLSGEKDHLHSVM 934
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLK 465
L+ ENK+L EI+ + E L K
Sbjct: 935 VHLQQENKKLKKEIEEKKMKAENTRLCTK 963
Score = 48.8 bits (111), Expect = 5e-05
Identities = 78/365 (21%), Positives = 167/365 (45%), Gaps = 54/365 (14%)
Query: 172 LITKNETD-INELRNSIKYLE---SVKSEYNTANEKLFEQLN----NAVDK-QNCIQEEV 222
L+ K + D I EL+ ++ L+ S+ + T+N K E+L+ A+ K +N +E+
Sbjct: 517 LLDKQKADTIQELQRELQMLQKESSMAEKEQTSNRKRVEELSLELSEALRKLENSDKEKR 576
Query: 223 DLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENF 282
L K + ++ + K +L+E T L+E+K ++K+ E+
Sbjct: 577 QLQKTVAEQDMKMNDMLDRIKHQHREQGSIKCKLEEDLQEA-TKLLEDKREQLKKSKEHE 635
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
K ++ +L R+EF ++K+ L + S+K+ + L + + + +E +
Sbjct: 636 K----LMEGELEALRQEF----KKKDKTLKENSRKLEEENENLRAELQCCSTQLESSLNK 687
Query: 343 ENNSYKLIENMFNKVS-QIASDFKISNQLSCELDDE--------SENTYERIS----LTL 389
N S ++I+++ +++ Q S + QL L E ++ Y+ +S
Sbjct: 688 YNTSQQVIQDLNKEIALQKESLMSLQAQLDKALQKEKHYLQTTITKEAYDALSRKSAACQ 747
Query: 390 DKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIE 449
D +T + LN +ET+ Q L + +++ A L E+ I +ER+ +L TE ++L
Sbjct: 748 DDLTQALEKLNHVTSETKSLQ--QSLTQTQEKKAQLEEEIIAYEERMKKLNTELRKL--- 802
Query: 450 IQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQ 509
RG ++E L + ++E+M +V++W+ Q ++ ++ +
Sbjct: 803 ----RGFHQESELEVH--------------AFDKKLEEMSCQVLQWQKQHQNDLKMLAAK 844
Query: 510 QKELK 514
+++L+
Sbjct: 845 EEQLR 849
Score = 34.3 bits (75), Expect = 1.1
Identities = 42/212 (19%), Positives = 89/212 (41%), Gaps = 17/212 (8%)
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+QE + ++ K K ++ L+EK E L L ++L +N+ K E K +A++
Sbjct: 382 LQELQLEFTETQKLTLKKDKFLQEKDEMLQELEKKLTQVQNSLLKK-EKELEKQQCMATE 440
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
+++ + + D E + + + K+ N + E ++ + A +Q A
Sbjct: 441 LEMTVK-EAKQDKSKEAECKALQAEVQKLKN-------SLEEAKQQERLAGEAPAAQQAA 492
Query: 424 DLTEQNIILKERLSQLETE-NKELLIEIQ---TVRGSNEEVTLNLKDSSTXXXXXXXXXX 479
E+ + L + + K LL++ Q T++ E+ + K+SS
Sbjct: 493 QCKEEAALAGCHLEDTQRKLQKGLLLDKQKADTIQELQRELQMLQKESS----MAEKEQT 548
Query: 480 XXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
+E++ ++ E + E+ D +Q QK
Sbjct: 549 SNRKRVEELSLELSEALRKLENSDKEKRQLQK 580
Score = 32.3 bits (70), Expect = 4.2
Identities = 50/229 (21%), Positives = 91/229 (39%), Gaps = 19/229 (8%)
Query: 284 QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTE 343
Q++ + +K + +E +E +QE L+ + + K E+ELE++Q T L + + +
Sbjct: 393 QKLTLKKDKFL---QEKDEMLQELEKKLTQVQNSLLKKEKELEKQQCMATELEMTVKEAK 449
Query: 344 NNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQI 403
+ K E K Q A K+ N L E + + +
Sbjct: 450 QDKSKEAE---CKALQ-AEVQKLKNSLEEAKQQERLAGEAPAAQQAAQCKEEAALAGCHL 505
Query: 404 NETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLN 463
+TQ+ LL + KQ AD ++ L+ L L+ E+ E + R EE++L
Sbjct: 506 EDTQRKLQKGLLLD--KQKADTIQE---LQRELQMLQKESSMAEKEQTSNRKRVEELSLE 560
Query: 464 LKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
L ++ E ++ V E + D+ D +K Q +E
Sbjct: 561 LSEA-------LRKLENSDKEKRQLQKTVAEQDMKMNDMLDRIKHQHRE 602
>AY739715-1|AAW65984.1| 617|Homo sapiens M-phase phosphoprotein 1
protein.
Length = 617
Score = 50.4 bits (115), Expect = 1e-05
Identities = 57/277 (20%), Positives = 127/277 (45%), Gaps = 30/277 (10%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE-----KLICDRREFNETMQEKNILLS 312
A ++E++T+L +K+ E+ + K E D+L + KL + +EF E +Q+
Sbjct: 56 AKIKELETILETQKV----ERSHSAKLEQDILEKESIILKLERNLKEFQEHLQDSVKNTK 111
Query: 313 DLSKKVNKTERELEE---KQEQLTHLMEQLNDTENNSYKLIENMFNKVS-------QIAS 362
DL+ K K + E+ + + + HL++ + E + + E + ++S + +
Sbjct: 112 DLNVKELKLKEEITQLTNNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKA 171
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKIT---NHITYLNTQINETQKNDN--AQLLWE 417
D + + +L ++ + ++I +++ + L +INE +K N +Q L
Sbjct: 172 DLQRKEEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKINELEKKKNQCSQELDM 231
Query: 418 AKKQIADLTEQ--NIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXX 475
++ I L EQ N ++E + Q E K+L ++ + + E++ + L++
Sbjct: 232 KQRTIQQLKEQLNNQKVEEAIQQYERACKDLNVKEKII----EDMRMTLEEQEQTQVEQD 287
Query: 476 XXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
E+E + T++ +WK + DL+ Q+ +
Sbjct: 288 QVLEAKLEEVERLATELEKWKEKCNDLETKNNQRSNK 324
Score = 50.0 bits (114), Expect = 2e-05
Identities = 83/429 (19%), Positives = 184/429 (42%), Gaps = 41/429 (9%)
Query: 90 KHNDLKKLYEDSASELEALKRENIQMH-TSDVMV--VPEIIDSLTEVINTLTNGFESLEE 146
+H + L ++ + ++ LK E + + T DV + V E +L+E+ +T ++E
Sbjct: 1 EHKNQDDLLKEKETLIQQLKEELQEKNVTLDVQIQHVVEGKRALSELTQGVTCYKAKIKE 60
Query: 147 VALEIDLKKNSITKDNISIKTLLDK--LITKNETDINELRNSIKYLESVKS--EYNTANE 202
+ ++ +K + + +L+K +I K E ++ E + ++ +SVK+ + N
Sbjct: 61 LETILETQKVERSHSAKLEQDILEKESIILKLERNLKEFQEHLQ--DSVKNTKDLNVKEL 118
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
KL E++ N +Q+ LL+++ + A+L+
Sbjct: 119 KLKEEITQLT---NNLQDMKHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQR 175
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
EE +++KEK + K++I + +K + R+ ++ ++ K +++L KK N+
Sbjct: 176 K-----EEDYADLKEKLTDAKKQIKQV-QKEVSVMRDEDKLLRIK---INELEKKKNQCS 226
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
+EL+ KQ + L EQLN+ + +E + + D + ++ ++ E
Sbjct: 227 QELDMKQRTIQQLKEQLNNQK------VEEAIQQYERACKDLNVKEKIIEDMRMTLEE-Q 279
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
E+ + D++ L ++ E ++ W K++ DL +N +R ++
Sbjct: 280 EQTQVEQDQV------LEAKLEEVERLATELEKW--KEKCNDLETKN---NQRSNKEHEN 328
Query: 443 NKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDL 502
N ++L ++ ++ +E + E E+++ K E K ED
Sbjct: 329 NTDVLGKLTNLQDELQESEQKYNADRKKWLEEKMMLITQAKEAENIRNK--EMKKYAEDR 386
Query: 503 DDVMKQQQK 511
+ KQQ +
Sbjct: 387 ERFFKQQNE 395
Score = 32.3 bits (70), Expect = 4.2
Identities = 65/350 (18%), Positives = 146/350 (41%), Gaps = 22/350 (6%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQ---LXXXXXXXXXXXXXLTEKLTIA 87
+EI QL + LQ K + +LK +E + ++ L L L
Sbjct: 122 EEITQLTNNLQDM-----KHLLQLKEEEEETNRQETEKLKEELSASSARTQNLKADLQRK 176
Query: 88 ETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEV 147
E + DLK+ D+ +++ +++E M D ++ +I + L + N + + +
Sbjct: 177 EEDYADLKEKLTDAKKQIKQVQKEVSVMRDEDKLLRIKI-NELEKKKNQCSQELDMKQRT 235
Query: 148 ALEI-DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFE 206
++ + N ++ I K + E I ++R +++ E + E + E E
Sbjct: 236 IQQLKEQLNNQKVEEAIQQYERACKDLNVKEKIIEDMRMTLEEQEQTQVEQDQVLEAKLE 295
Query: 207 QLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM--- 263
++ + +E+ + +E +N + +D+ + ++
Sbjct: 296 EVERLATELEKWKEKCN--DLETKNNQRSNKEHENNTDVLGKLTNLQDELQESEQKYNAD 353
Query: 264 KTMLVEEKLSEIKE--KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
+ +EEK+ I + + EN + + +M +K DR F + E IL + L++K +
Sbjct: 354 RKKWLEEKMMLITQAKEAENIRNK-EM--KKYAEDRERFFKQQNEMEILTAQLTEKDSDL 410
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQL 370
++ EE+ + + L QL +++ + +N ++ +I S+ KI Q+
Sbjct: 411 QKWREERDQLVAALEIQLKALISSNVQK-DNEIEQLKRIISETSKIETQI 459
>AY518538-1|AAT44534.1| 1179|Homo sapiens rhabdomyosarcoma antigen
MU-RMS-40.7B protein.
Length = 1179
Score = 50.4 bits (115), Expect = 1e-05
Identities = 95/492 (19%), Positives = 197/492 (40%), Gaps = 44/492 (8%)
Query: 41 QQNVGVGDKTVAEL-KND-EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLY 98
Q N+ ++ +L KN ++ + ++++ LT K E + ++LK+
Sbjct: 139 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 198
Query: 99 EDSASELEALKREN------IQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+D L +++E ++ T ++ + EII LT+ L + +L+++ E
Sbjct: 199 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 258
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
D K N++TK + K E +++L S++ + V+ + A KL L
Sbjct: 259 D-KVNTLTKAKV-----------KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-- 304
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +++ + E D +++ + L + + L+E++ + E+
Sbjct: 305 LTQESIMDLENDKQQLD-ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARI--EE 361
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS---DLSKK----VNKTERE 324
L E E + + +++ L L + E +E ++E S +++KK K R+
Sbjct: 362 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 421
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYE 383
LEE Q L +S + + + ++ K ++ ELDD + N E
Sbjct: 422 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-ME 480
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL--ET 441
+I + L Q+NE + E ++ + DLT Q L+ +L +
Sbjct: 481 QIIKAKANLEKMCRTLEDQMNEHRSKAE-----ETQRSVNDLTSQQAKLQTENGELSRQL 535
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ KE LI Q RG T L+D ++ ++ + + Q+E+
Sbjct: 536 DEKEALIS-QLTRG-KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 593
Query: 502 LDDVMKQQQKEL 513
+ + Q+ L
Sbjct: 594 ETEAKAELQRVL 605
Score = 40.7 bits (91), Expect = 0.012
Identities = 50/260 (19%), Positives = 108/260 (41%), Gaps = 30/260 (11%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDL 314
ANLE+M L E++++E + K E ++ ++ L KL + E + + EK L+S L
Sbjct: 487 ANLEKMCRTL-EDQMNEHRSKAEETQRSVNDLTSQQAKLQTENGELSRQLDEKEALISQL 545
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++ ++LE+ + QL E+ +N +++ + + ++ + EL
Sbjct: 546 TRGKLTYTQQLEDLKRQL----EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 601
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+R+ L K + + T+ ET + L EAKK++A +
Sbjct: 602 --------QRV---LSKANSEVAQWRTKY-ETDAIQRTEELEEAKKKLA----------Q 639
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
RL + E + + + ++ + + ++D + + + E
Sbjct: 640 RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 699
Query: 495 WKSQFEDLDDVMKQQQKELK 514
WK ++E+ ++ QKE +
Sbjct: 700 WKQKYEESQSELESSQKEAR 719
Score = 39.9 bits (89), Expect = 0.021
Identities = 60/311 (19%), Positives = 122/311 (39%), Gaps = 23/311 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 728 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 787
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLD-KLITKNETDINELRNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK ++ KL K+E RN ++ ++S+++ +
Sbjct: 788 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 847
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E L + + E L N+ + D +
Sbjct: 848 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 907
Query: 260 LEEMK--TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K +VE + + ++ + E + ++ +E ET + +L S +
Sbjct: 908 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 967
Query: 318 VN---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+N K + +L + Q ++ +++ + E + K I + + +A + K S L
Sbjct: 968 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD----AAMMAEELKKEQDTSAHL 1023
Query: 375 DDESENTYERI 385
+ +N + I
Sbjct: 1024 ERMKKNMEQTI 1034
Score = 36.7 bits (81), Expect = 0.20
Identities = 92/409 (22%), Positives = 163/409 (39%), Gaps = 43/409 (10%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q ++ V + + L+ + + + I L L +K
Sbjct: 630 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 689
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF-E 142
+ + K+ YE+S SELE+ ++E SL+ + L N + E
Sbjct: 690 QRNFDKILAEWKQKYEESQSELESSQKE---------------ARSLSTELFKLKNAYEE 734
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
SLE LE ++N ++ IS L ++L + +T I+EL K LE+ K E +A E
Sbjct: 735 SLEH--LETFKRENKNLQEEIS--DLTEQLGSSGKT-IHELEKVRKQLEAEKMELQSALE 789
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ L + K Q E + +K E + L A+ + ++
Sbjct: 790 EAEASLEHEEGKILRAQLEFNQIKAEIERKL---------AEKDEEMEQAKRNHLRVVDS 840
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
++T L E S + K E D LNE I N E + L + T+
Sbjct: 841 LQTSLDAETRSRNEALRVKKKMEGD-LNEMEI-QLSHANRMAAEAQKQVKSLQSLLKDTQ 898
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKL---IENMFNKVSQIASDFKISNQLSCELDDESE 379
+L++ L E + E + L +E + V Q K++ Q E + +
Sbjct: 899 IQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ 958
Query: 380 NTYERISLTLD---KITNHITYLNTQINE-TQKNDNAQLLWEAKKQIAD 424
+ + + ++ K+ ++ L T++ E Q+ NA+ +AKK I D
Sbjct: 959 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE--EKAKKAITD 1005
Score = 35.5 bits (78), Expect = 0.46
Identities = 38/222 (17%), Positives = 98/222 (44%), Gaps = 6/222 (2%)
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+R + +M+E+ L + +K +ELEEK + L+++ ND + +N+ +
Sbjct: 88 EREKEMASMKEEFTRLKEALEKSEARRKELEEK---MVSLLQEKNDLQLQVQAEQDNLAD 144
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQL 414
+ K QL ++ + +E + + + +T L + +E +++ D+ +L
Sbjct: 145 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKRDIDDLEL 203
Query: 415 LWEAKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 204 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 263
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 264 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 305
>AY264265-1|AAP20418.1| 1357|Homo sapiens kinectin variant 1
protein.
Length = 1357
Score = 50.4 bits (115), Expect = 1e-05
Identities = 79/482 (16%), Positives = 202/482 (41%), Gaps = 31/482 (6%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
K A D + +++ + +++ E +HN + S E + +
Sbjct: 345 KEDAAATKDRCKQLTQEMMTEKERSNVVITRMKDRIGTLEKEHNVFQNKIHVSYQETQQM 404
Query: 109 KRENIQMHT---SDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISI 165
+ + Q+ +++ + + L + ++ TN ES + L N + +D +
Sbjct: 405 QMKFQQVREQMEAEIAHLKQENGILRDAVSNTTNQLESKQSAEL------NKLRQDYARL 458
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNC----IQEE 221
L + K + + + +N+ + +K + A E+ +E++ + + K+ Q++
Sbjct: 459 VNELTEKTGKLQQEEVQKKNAEQAATQLKVQLQEA-ERRWEEVQSYIRKRTAEHEAAQQD 517
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE---KLSEIKEK 278
+ + +N +Q R + E+ + E ++ +I E+
Sbjct: 518 LQSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRVNKEESLQMQVQDILEQ 577
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQ 338
+E K +I + + I + + +E + ++++ K++ +TE L ++++LT E+
Sbjct: 578 NEALKAQIQQFHSQ-IAAQTSASVLAEELHKVIAEKDKQIKQTEDSLASERDRLTSKEEE 636
Query: 339 LNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY---ERISLTLDKITNH 395
L D +N ++ L++ K+ +A++ + EL+ ++ Y ++I L +++ +
Sbjct: 637 LKDIQNMNF-LLKAEVQKLQALANE---QAAAAHELEKMQQSVYVKDDKIRLLEEQLQHE 692
Query: 396 ITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRG 455
I+ + + + N L E +K ++EQ K+ + Q+E +E +++TV
Sbjct: 693 ISNKMEEF-KILNDQNKALKSEVQKLQTLVSEQP--NKDVVEQMEKCIQEKDEKLKTVEE 749
Query: 456 SNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTK---VMEWKSQFEDLDDVMKQQQKE 512
E + + + E++D+K K + + S E+L V+ ++ +
Sbjct: 750 LLETGLIQVATKEEELNAIRTENSSLTKEVQDLKAKQNDQVSFASLVEELKKVIHEKDGK 809
Query: 513 LK 514
+K
Sbjct: 810 IK 811
Score = 46.4 bits (105), Expect = 2e-04
Identities = 64/355 (18%), Positives = 147/355 (41%), Gaps = 27/355 (7%)
Query: 20 HAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKN-DEINSMIRQLXXXXXXXXXXXX 78
H ++EE +K + L+ V V+E N D + M + +
Sbjct: 691 HEISNKMEE-FKILNDQNKALKSEVQKLQTLVSEQPNKDVVEQMEKCIQEKDEKLKTVEE 749
Query: 79 XLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLT 138
L L TK +L + +++S + + ++++ +D + +++ L +VI+
Sbjct: 750 LLETGLIQVATKEEELNAIRTENSSLTKEV--QDLKAKQNDQVSFASLVEELKKVIHEKD 807
Query: 139 NGFESLEEVA----LEIDLKKNSITKDNISIKTLLDKL----ITKNE-----TDINELRN 185
+S+EE+ L++ K+ ++ IK L +++ + K + + + EL+N
Sbjct: 808 GKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNVQLEKAQQLSITSKVQELQN 867
Query: 186 SIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXX 245
+K E + E+ + L N +QEE + LK Q + Q
Sbjct: 868 LLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLKAHVQEVAQHNLKEASSASQ 927
Query: 246 XXXXXXARDKFIANLEEMKTMLVEEK---------LSEIKEKDENFKQEIDMLNEKLICD 296
+ L+ ++ ML E + L +++++++ FK +I+ L ++
Sbjct: 928 FEELEIVLKEKENELKRLEAMLKERESDLSSKTQLLQDVQDENKLFKSQIEQLKQQNYQQ 987
Query: 297 RREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIE 351
F +E ++S+ K+++ EL+ ++ + H ++ ND +++ +E
Sbjct: 988 ASSF-PPHEELLKVISEREKEISGLWNELDSLKDAVEHQRKKNNDLREKNWEAME 1041
Score = 43.6 bits (98), Expect = 0.002
Identities = 76/335 (22%), Positives = 148/335 (44%), Gaps = 46/335 (13%)
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARD----KFIANLEEMKTM 266
A ++ +E +L I+N N L A + + +++ K
Sbjct: 624 ASERDRLTSKEEELKDIQNMNFLLKAEVQKLQALANEQAAAAHELEKMQQSVYVKDDKIR 683
Query: 267 LVEEKLS-EIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK--VNKTER 323
L+EE+L EI K E FK +LN++ + +Q+ L+S+ K V + E+
Sbjct: 684 LLEEQLQHEISNKMEEFK----ILNDQ----NKALKSEVQKLQTLVSEQPNKDVVEQMEK 735
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYE 383
++EK E+L +E+L +T LI+ + K ++ + ++ L+ E+ D +
Sbjct: 736 CIQEKDEKLK-TVEELLETG-----LIQ-VATKEEELNAIRTENSSLTKEVQDLKAKQND 788
Query: 384 RISLT--LDKITNHITYLNTQINETQKNDNAQLLWEAKKQ--IADLTEQNIILKERLSQL 439
++S ++++ I + +I ++ A+LL A K+ + DL ++ LKE + +
Sbjct: 789 QVSFASLVEELKKVIHEKDGKIKSVEELLEAELLKVANKEKTVQDLKQEIKALKEEIGNV 848
Query: 440 ETENKELLI------EIQTV-RGSNEEV-TLN--LKDSSTXXXXXXXXXXXXSNEIEDMK 489
+ E + L E+Q + +G E++ T+ L++ E E +K
Sbjct: 849 QLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQEENESLK 908
Query: 490 TKVMEWK----------SQFEDLDDVMKQQQKELK 514
V E SQFE+L+ V+K+++ ELK
Sbjct: 909 AHVQEVAQHNLKEASSASQFEELEIVLKEKENELK 943
Score = 37.1 bits (82), Expect = 0.15
Identities = 23/91 (25%), Positives = 49/91 (53%), Gaps = 5/91 (5%)
Query: 253 RDKFIANLEEMKTMLVEEK-LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
+ F ++ +E++ + E K + ++ + E+ + E+ EK +R + ++E LL
Sbjct: 1179 QSSFTSSEQELERLRSENKDIENLRREREHLEMEL----EKAEMERSTYVTEVRELKDLL 1234
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
++L KK++ + E + E+L L QLN+T
Sbjct: 1235 TELQKKLDDSYSEAVRQNEELNLLKAQLNET 1265
Score = 32.7 bits (71), Expect = 3.2
Identities = 38/193 (19%), Positives = 82/193 (42%), Gaps = 12/193 (6%)
Query: 160 KDNISIKTLLDKLITKNETDINELRNSIKYLE-SVKSEYNTANEKLFEQLNNAVDKQNCI 218
K+ + TLL K ++ + E ++ L+ SV+ E N K+ E Q+
Sbjct: 1123 KEADEMHTLLQLECEKYKSVLAETEGILQKLQRSVEQEENKWKVKVDESHKTIKQMQSSF 1182
Query: 219 ---QEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEI 275
++E++ L+ EN+++ R ++ + E+K +L +E+
Sbjct: 1183 TSSEQELERLRSENKDIENLRREREHLEMELEKAEMERSTYVTEVRELKDLL-----TEL 1237
Query: 276 KEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK---KVNKTERELEEKQEQL 332
++K ++ E NE+L + + NET+ + ++ K ++K ++ LE Q ++
Sbjct: 1238 QKKLDDSYSEAVRQNEELNLLKAQLNETLTKLRTEQNERQKVAGDLHKAQQSLELIQSKI 1297
Query: 333 THLMEQLNDTENN 345
EN+
Sbjct: 1298 VKAAGDTTVIENS 1310
Score = 31.9 bits (69), Expect = 5.6
Identities = 64/314 (20%), Positives = 133/314 (42%), Gaps = 27/314 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNG- 140
EK+ + +D +L E+ + K E ++ + + L +++ N
Sbjct: 669 EKMQQSVYVKDDKIRLLEEQLQHEISNKMEEFKILNDQNKALKSEVQKLQTLVSEQPNKD 728
Query: 141 -FESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR--NS--IKYLESVKS 195
E +E+ E D K ++ + ++T L ++ TK E ++N +R NS K ++ +K+
Sbjct: 729 VVEQMEKCIQEKDEKLKTVEE---LLETGLIQVATKEE-ELNAIRTENSSLTKEVQDLKA 784
Query: 196 EYN--TANEKLFEQLNNAV-DKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXA 252
+ N + L E+L + +K I+ +LL+ E LL+
Sbjct: 785 KQNDQVSFASLVEELKKVIHEKDGKIKSVEELLEAE---LLKVANKEKTVQDLKQEIKAL 841
Query: 253 RDKF-IANLEEMKTMLVEEKLSEI------KEKDENFKQEIDMLNEKLICDRREFNETMQ 305
+++ LE+ + + + K+ E+ KE+ N + + EK + + ++ + +Q
Sbjct: 842 KEEIGNVQLEKAQQLSITSKVQELQNLLKGKEEQMNTMKAVLEEKEKDLANTGKWLQDLQ 901
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
E+N L ++V + + Q L L + E N K +E M + + SD
Sbjct: 902 EENESLKAHVQEVAQHNLKEASSASQFEELEIVLKEKE-NELKRLEAM---LKERESDLS 957
Query: 366 ISNQLSCELDDESE 379
QL ++ DE++
Sbjct: 958 SKTQLLQDVQDENK 971
>AJ238393-1|CAC20413.1| 1935|Homo sapiens beta-myosin heavy chain
protein.
Length = 1935
Score = 50.4 bits (115), Expect = 1e-05
Identities = 95/492 (19%), Positives = 197/492 (40%), Gaps = 44/492 (8%)
Query: 41 QQNVGVGDKTVAEL-KND-EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLY 98
Q N+ ++ +L KN ++ + ++++ LT K E + ++LK+
Sbjct: 895 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 954
Query: 99 EDSASELEALKREN------IQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+D L +++E ++ T ++ + EII LT+ L + +L+++ E
Sbjct: 955 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 1014
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
D K N++TK + K E +++L S++ + V+ + A KL L
Sbjct: 1015 D-KVNTLTKAKV-----------KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-- 1060
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +++ + E D +++ + L + + L+E++ + E+
Sbjct: 1061 LTQESIMDLENDKQQLD-ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARI--EE 1117
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS---DLSKK----VNKTERE 324
L E E + + +++ L L + E +E ++E S +++KK K R+
Sbjct: 1118 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRD 1177
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYE 383
LEE Q L +S + + + ++ K ++ ELDD + N E
Sbjct: 1178 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-ME 1236
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL--ET 441
+I + L Q+NE + E ++ + DLT Q L+ +L +
Sbjct: 1237 QIIKAKANLEKMCRTLEDQMNEHRSKAE-----ETQRSVNDLTSQRAKLQTENGELSRQL 1291
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ KE LI Q RG T L+D ++ ++ + + Q+E+
Sbjct: 1292 DEKEALIS-QLTRG-KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 1349
Query: 502 LDDVMKQQQKEL 513
+ + Q+ L
Sbjct: 1350 ETEAKAELQRVL 1361
Score = 41.9 bits (94), Expect = 0.005
Identities = 83/465 (17%), Positives = 178/465 (38%), Gaps = 43/465 (9%)
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLT-EVINTLTNGFE 142
LT A+ K L++ +D LE K+ + + + + ++ LT E I L N +
Sbjct: 1020 LTKAKVK---LEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDL--KLTQESIMDLENDKQ 1074
Query: 143 SLEEVALEIDLKKNSIT---KDNISIKTLLDKLITKNETDINELRNSIKY-------LES 192
L+E + D + N++ +D ++ + L K + + + I EL ++ +E
Sbjct: 1075 QLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAKVEK 1134
Query: 193 VKSEYNTANEKLFEQLNNAVDKQNCIQE-----EVDLLKIEN---QNLLQXXXXXXXXXX 244
++S+ + E++ E+L A +C E E + K+ + LQ
Sbjct: 1135 LRSDLSRELEEISERLEEAGGATSCQIEMNKKREAEFQKMRRDLEEATLQHEATAAALRK 1194
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLS---EIKEKDENFKQEIDM-LNEKLIC----- 295
+ I NL+ +K L +EK E+ + N +Q I N + +C
Sbjct: 1195 KHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCRTLED 1254
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
E +E ++DL+ + K + E E QL ++ + + +
Sbjct: 1255 QMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTYTQQLED 1314
Query: 356 KVSQIASDFKISNQLSCELD------DESENTYERISLTLDKITNHITYLNTQINETQKN 409
Q+ + K N L+ L D YE + ++ ++ N+++ + +
Sbjct: 1315 LKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKANSEVAQWRTK 1374
Query: 410 DNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSST 469
+A ++ +L E L +RL + E + + + ++ + + ++D
Sbjct: 1375 YET----DAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMV 1430
Query: 470 XXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+ + + EWK ++E+ ++ QKE +
Sbjct: 1431 DVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEAR 1475
Score = 39.9 bits (89), Expect = 0.021
Identities = 60/311 (19%), Positives = 122/311 (39%), Gaps = 23/311 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLD-KLITKNETDINELRNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK ++ KL K+E RN ++ ++S+++ +
Sbjct: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E L + + E L N+ + D +
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 260 LEEMK--TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K +VE + + ++ + E + ++ +E ET + +L S +
Sbjct: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723
Query: 318 VN---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+N K + +L + Q ++ +++ + E + K I + + +A + K S L
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD----AAMMAEELKKEQDTSAHL 1779
Query: 375 DDESENTYERI 385
+ +N + I
Sbjct: 1780 ERMKKNMEQTI 1790
Score = 36.7 bits (81), Expect = 0.20
Identities = 92/409 (22%), Positives = 163/409 (39%), Gaps = 43/409 (10%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q ++ V + + L+ + + + I L L +K
Sbjct: 1386 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1445
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF-E 142
+ + K+ YE+S SELE+ ++E SL+ + L N + E
Sbjct: 1446 QRNFDKILAEWKQKYEESQSELESSQKE---------------ARSLSTELFKLKNAYEE 1490
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
SLE LE ++N ++ IS L ++L + +T I+EL K LE+ K E +A E
Sbjct: 1491 SLEH--LETFKRENKNLQEEIS--DLTEQLGSSGKT-IHELEKVRKQLEAEKMELQSALE 1545
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ L + K Q E + +K E + L A+ + ++
Sbjct: 1546 EAEASLEHEEGKILRAQLEFNQIKAEIERKL---------AEKDEEMEQAKRNHLRVVDS 1596
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
++T L E S + K E D LNE I N E + L + T+
Sbjct: 1597 LQTSLDAETRSRNEALRVKKKMEGD-LNEMEI-QLSHANRMAAEAQKQVKSLQSLLKDTQ 1654
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKL---IENMFNKVSQIASDFKISNQLSCELDDESE 379
+L++ L E + E + L +E + V Q K++ Q E + +
Sbjct: 1655 IQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ 1714
Query: 380 NTYERISLTLD---KITNHITYLNTQINE-TQKNDNAQLLWEAKKQIAD 424
+ + + ++ K+ ++ L T++ E Q+ NA+ +AKK I D
Sbjct: 1715 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE--EKAKKAITD 1761
Score = 35.5 bits (78), Expect = 0.46
Identities = 38/222 (17%), Positives = 98/222 (44%), Gaps = 6/222 (2%)
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+R + +M+E+ L + +K +ELEEK + L+++ ND + +N+ +
Sbjct: 844 EREKEMASMKEEFTRLKEALEKSEARRKELEEK---MVSLLQEKNDLQLQVQAEQDNLAD 900
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQL 414
+ K QL ++ + +E + + + +T L + +E +++ D+ +L
Sbjct: 901 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKRDIDDLEL 959
Query: 415 LWEAKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 1019
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 1020 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 1061
>AF112218-1|AAF17206.1| 742|Homo sapiens unknown protein.
Length = 742
Score = 50.4 bits (115), Expect = 1e-05
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
E+ Q ++ L+D K+ + +ELEEK EQL ++L E +L + N +S
Sbjct: 169 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 228
Query: 362 SDFKISNQLSC--ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
S ++L E + +S +++ + I + ++ E K DN Q+L E K
Sbjct: 229 SARMYRDELDALREKAVRVDKLESEVSRYKERL-HDIEFYKARVEEL-KEDN-QVLLETK 285
Query: 420 KQIADLTEQNIILKERLSQLETENKEL 446
+ D E ++L +LE EN +L
Sbjct: 286 TMLEDQLEGTRARSDKLHELEKENLQL 312
Score = 47.2 bits (107), Expect = 1e-04
Identities = 76/383 (19%), Positives = 170/383 (44%), Gaps = 21/383 (5%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDL 153
+ + E S + ++L E ++ +S ++ + SLT+ + L +S+E A +I L
Sbjct: 361 ISRTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKI-L 419
Query: 154 KKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVD 213
K + +L+ I + + + +N K L K++ EK E L +
Sbjct: 420 KMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSKDLMKEKAQL----EKTIETLRENSE 475
Query: 214 KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFI-ANLEEMKTML--VEE 270
+Q I E+ + + NQ + +K + +++E + L +E
Sbjct: 476 RQIKILEQEN--EHLNQTVSSLRQRSQISAEARVKDIEKENKILHESIKETSSKLSKIEF 533
Query: 271 KLSEIKEKDENFKQEIDMLNE--KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEK 328
+ +IK++ E++K++ + E + + NE +Q+K L +K+ E+E E
Sbjct: 534 EKRQIKKELEHYKEKGERAEELENELHHLEKENELLQKKITNLKITCEKIEALEQENSEL 593
Query: 329 QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF----KISNQLSCELDDESENTYER 384
+ + L + L+ +N +++L E++ + SQ+ + + L C ++ E
Sbjct: 594 ERENRKLKKTLDSFKNLTFQL-ESLEKENSQLDEENLELRRNVESLKCASMKMAQLQLEN 652
Query: 385 ISLTLDK--ITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
L +K + + L +T++ + + + + Q T +N +++ QLE+E
Sbjct: 653 KELESEKEQLKKGLELLKASFKKTERLEVSYQGLDIENQRLQKTLENS--NKKIQQLESE 710
Query: 443 NKELLIEIQTVRGSNEEVTLNLK 465
++L +E QT++ + EE+ ++ K
Sbjct: 711 LQDLEMENQTLQKNLEELKISSK 733
Score = 35.1 bits (77), Expect = 0.60
Identities = 83/452 (18%), Positives = 176/452 (38%), Gaps = 30/452 (6%)
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
+ + + D++ L ++ A L+ L E + H+ ++ + E D L + + ++
Sbjct: 101 MEVTDMSQEDIEPLLKNMALHLKRLIDERDE-HSETIIELSEERDGLHFLPHASSSAQSP 159
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
++ + ++ + K + +L + E +L + + LE ++ E ++
Sbjct: 160 CGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE 219
Query: 204 LFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN-- 259
L++A + ++E+D L K + L+ AR + +
Sbjct: 220 NMNLLSDARSAR-MYRDELDALREKAVRVDKLESEVSRYKERLHDIEFYKARVEELKEDN 278
Query: 260 --LEEMKTMLVEE---------KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
L E KTML ++ KL E+++++ K ++ + + DR++ E M+E N
Sbjct: 279 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEE-N 337
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN 368
+ L K+ L + EQ++ E L++ S L + S ++ N
Sbjct: 338 MTLEMAQKQSMDESLHLGWELEQISRTSE-LSEAPQKS--LGHEVNELTSSRLLKLEMEN 394
Query: 369 QLSCELDDESENTYERISLTLDKI-----TNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
Q + +E T + + KI N +I E + Q L +
Sbjct: 395 QSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEILENEIVQEKQSLQNCQNLSK 454
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL-NLKDSSTXXXXXXXXXXXXS 482
DL ++ L++ + L EN E I+I + T+ +L+ S
Sbjct: 455 DLMKEKAQLEKTIETLR-ENSERQIKILEQENEHLNQTVSSLRQRSQISAEARVKDIEKE 513
Query: 483 NEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
N+I + + E S+ ++ +Q +KEL+
Sbjct: 514 NKI--LHESIKETSSKLSKIEFEKRQIKKELE 543
>AB209708-1|BAD92945.1| 1574|Homo sapiens myosin, heavy polypeptide 7,
cardiac muscle, beta variant protein.
Length = 1574
Score = 50.4 bits (115), Expect = 1e-05
Identities = 95/492 (19%), Positives = 197/492 (40%), Gaps = 44/492 (8%)
Query: 41 QQNVGVGDKTVAEL-KND-EINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLY 98
Q N+ ++ +L KN ++ + ++++ LT K E + ++LK+
Sbjct: 534 QDNLADAEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKRDI 593
Query: 99 EDSASELEALKREN------IQMHTSDVMVVPEIIDSLTEVINTLTNGFE-SLEEVALEI 151
+D L +++E ++ T ++ + EII LT+ L + +L+++ E
Sbjct: 594 DDLELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEE 653
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNA 211
D K N++TK + K E +++L S++ + V+ + A KL L
Sbjct: 654 D-KVNTLTKAKV-----------KLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLK-- 699
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +++ + E D +++ + L + + L+E++ + E+
Sbjct: 700 LTQESIMDLENDKQQLD-ERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARI--EE 756
Query: 272 LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS---DLSKK----VNKTERE 324
L E E + + +++ L L + E +E ++E S +++KK K R+
Sbjct: 757 LEEELEAERTARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRD 816
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-KISNQLSCELDDESENTYE 383
LEE Q L +S + + + ++ K ++ ELDD + N E
Sbjct: 817 LEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSN-ME 875
Query: 384 RISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQL--ET 441
+I + L Q+NE + E ++ + DLT Q L+ +L +
Sbjct: 876 QIIKAKANLEKMCRTLEDQMNEHRSKAE-----ETQRSVNDLTSQRAKLQTENGELSRQL 930
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFED 501
+ KE LI Q RG T L+D ++ ++ + + Q+E+
Sbjct: 931 DEKEALIS-QLTRG-KLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEE 988
Query: 502 LDDVMKQQQKEL 513
+ + Q+ L
Sbjct: 989 ETEAKAELQRVL 1000
Score = 40.7 bits (91), Expect = 0.012
Identities = 50/260 (19%), Positives = 108/260 (41%), Gaps = 30/260 (11%)
Query: 258 ANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDL 314
ANLE+M L E++++E + K E ++ ++ L KL + E + + EK L+S L
Sbjct: 882 ANLEKMCRTL-EDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQL 940
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
++ ++LE+ + QL E+ +N +++ + + ++ + EL
Sbjct: 941 TRGKLTYTQQLEDLKRQL----EEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAEL 996
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+R+ L K + + T+ ET + L EAKK++A +
Sbjct: 997 --------QRV---LSKANSEVAQWRTKY-ETDAIQRTEELEEAKKKLA----------Q 1034
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
RL + E + + + ++ + + ++D + + + E
Sbjct: 1035 RLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAE 1094
Query: 495 WKSQFEDLDDVMKQQQKELK 514
WK ++E+ ++ QKE +
Sbjct: 1095 WKQKYEESQSELESSQKEAR 1114
Score = 39.9 bits (89), Expect = 0.021
Identities = 60/311 (19%), Positives = 122/311 (39%), Gaps = 23/311 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 1123 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1182
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLD-KLITKNETDINELRNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK ++ KL K+E RN ++ ++S+++ +
Sbjct: 1183 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1242
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E L + + E L N+ + D +
Sbjct: 1243 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1302
Query: 260 LEEMK--TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K +VE + + ++ + E + ++ +E ET + +L S +
Sbjct: 1303 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1362
Query: 318 VN---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+N K + +L + Q ++ +++ + E + K I + + +A + K S L
Sbjct: 1363 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD----AAMMAEELKKEQDTSAHL 1418
Query: 375 DDESENTYERI 385
+ +N + I
Sbjct: 1419 ERMKKNMEQTI 1429
Score = 36.7 bits (81), Expect = 0.20
Identities = 92/409 (22%), Positives = 163/409 (39%), Gaps = 43/409 (10%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q ++ V + + L+ + + + I L L +K
Sbjct: 1025 LEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKK 1084
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF-E 142
+ + K+ YE+S SELE+ ++E SL+ + L N + E
Sbjct: 1085 QRNFDKILAEWKQKYEESQSELESSQKE---------------ARSLSTELFKLKNAYEE 1129
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANE 202
SLE LE ++N ++ IS L ++L + +T I+EL K LE+ K E +A E
Sbjct: 1130 SLEH--LETFKRENKNLQEEIS--DLTEQLGSSGKT-IHELEKVRKQLEAEKMELQSALE 1184
Query: 203 KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
+ L + K Q E + +K E + L A+ + ++
Sbjct: 1185 EAEASLEHEEGKILRAQLEFNQIKAEIERKL---------AEKDEEMEQAKRNHLRVVDS 1235
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
++T L E S + K E D LNE I N E + L + T+
Sbjct: 1236 LQTSLDAETRSRNEALRVKKKMEGD-LNEMEI-QLSHANRMAAEAQKQVKSLQSLLKDTQ 1293
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKL---IENMFNKVSQIASDFKISNQLSCELDDESE 379
+L++ L E + E + L +E + V Q K++ Q E + +
Sbjct: 1294 IQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQ 1353
Query: 380 NTYERISLTLD---KITNHITYLNTQINE-TQKNDNAQLLWEAKKQIAD 424
+ + + ++ K+ ++ L T++ E Q+ NA+ +AKK I D
Sbjct: 1354 LLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE--EKAKKAITD 1400
Score = 35.5 bits (78), Expect = 0.46
Identities = 38/222 (17%), Positives = 98/222 (44%), Gaps = 6/222 (2%)
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+R + +M+E+ L + +K +ELEEK + L+++ ND + +N+ +
Sbjct: 483 EREKEMASMKEEFTRLKEALEKSEARRKELEEK---MVSLLQEKNDLQLQVQAEQDNLAD 539
Query: 356 KVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQL 414
+ K QL ++ + +E + + + +T L + +E +++ D+ +L
Sbjct: 540 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAE-LTAKKRKLEDECSELKRDIDDLEL 598
Query: 415 LWEAKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXX 473
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 599 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDKVNT 658
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
+++D++ + + K DL+ ++ + +LKL
Sbjct: 659 LTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKL 700
>AB067524-1|BAB67830.1| 704|Homo sapiens KIAA1937 protein protein.
Length = 704
Score = 50.4 bits (115), Expect = 1e-05
Identities = 49/279 (17%), Positives = 123/279 (44%), Gaps = 7/279 (2%)
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE-NQNLLQXXXXXX 240
+LR + E + E EKL ++ +++ ++E + + + L +
Sbjct: 20 KLREHLAEKEKLNEERLEQEEKLKAKIRQLTEEKAALEEYITQERNRAKETLEEERKRMQ 79
Query: 241 XXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF 300
A K I + +EE+ + ++E +E ++ ++ + ++R+
Sbjct: 80 ELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLARQKEISESNIAYEKRKA 139
Query: 301 NETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
E M+++ + DL ++ K + ELE K+++ L +L+D + E K ++
Sbjct: 140 KEAMEKEKKKVQDLENRLTKQKEELELKEQKEDVLNNKLSDA---LAMVEETQKTKATES 196
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDK--ITNHITYLNTQINETQKNDNAQLLWEA 418
++ +L+ E E E T ++ + ++ + + E+Q++ + + E
Sbjct: 197 LKAESLALKLN-ETLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFGEEIMEY 255
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSN 457
K+QI + + L+E+L ++ +K++ EI T++ ++
Sbjct: 256 KEQIKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLKDND 294
Score = 35.5 bits (78), Expect = 0.46
Identities = 50/228 (21%), Positives = 89/228 (39%), Gaps = 21/228 (9%)
Query: 266 MLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
+ +EEKL E + E +E EKL R+ E EK L ++++ N+ + L
Sbjct: 15 LFLEEKLREHLAEKEKLNEERLEQEEKLKAKIRQLTE---EKAALEEYITQERNRAKETL 71
Query: 326 EEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI 385
EE+++++ L L + K I N+V + + + Q EL+ ER+
Sbjct: 72 EEERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQ---ELE-------ERL 121
Query: 386 SLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
+ + ++I Y + E + + KK++ DL + KE L E +
Sbjct: 122 ARQKEISESNIAYEKRKAKEAMEKE--------KKKVQDLENRLTKQKEELELKEQKEDV 173
Query: 446 LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
L ++ EE S E+E KTK++
Sbjct: 174 LNNKLSDALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMI 221
>Z82215-4|CAB05105.1| 1960|Homo sapiens myosin, heavy chain 9,
non-muscle protein.
Length = 1960
Score = 50.0 bits (114), Expect = 2e-05
Identities = 69/354 (19%), Positives = 144/354 (40%), Gaps = 23/354 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLL--- 233
+ + +++ +I+ LE E +A +KL + K ++EE +L+ +N L
Sbjct: 935 QAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEK 994
Query: 234 QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL 293
+ + K +A L+ ++ + L E ++E +QE++ KL
Sbjct: 995 KLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD-LEERLRREEKQRQELEKTRRKL 1053
Query: 294 ICDRREFNETMQEKNILLSDLSKKVNKTEREL-------EEKQEQLTHLMEQLNDTENNS 346
D + ++ + E +++L ++ K E EL EE+ Q ++++ + E+
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 347 YKLIENM------FNKVSQIASDF-KISNQLSCELDDESENTYERISLTLDKITNHITYL 399
+L E++ NK + D + L EL+D ++T + L K + L
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR-SKREQEVNIL 1172
Query: 400 NTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
+ E K AQ + E +++ + E+ L E+L Q + L QT+ E
Sbjct: 1173 KKTLEEEAKTHEAQ-IQEMRQKHSQAVEE---LAEQLEQTKRVKANLEKAKQTLENERGE 1228
Query: 460 VTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
+ +K ++++++ K E + +L D + + Q EL
Sbjct: 1229 LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Score = 49.2 bits (112), Expect = 3e-05
Identities = 78/391 (19%), Positives = 160/391 (40%), Gaps = 35/391 (8%)
Query: 157 SITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQN 216
++T++ K+L KL K+E I +L ++ E + E KL + D+
Sbjct: 1007 NLTEEEEKSKSLA-KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 217 CIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIK 276
+Q ++ LK++ + K I LE + L E+ SE
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 277 EKDENFKQEIDMLNEKLICDRREFNETM--------------QEKNILLSDLSKKVNKTE 322
+++ KQ+ D L E+L + E +T+ QE NIL L ++ E
Sbjct: 1126 SRNKAEKQKRD-LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 323 RELEEKQ-------EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+++E + E+L +EQ + N K + + N+ ++A++ K+ Q + +
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSE 1244
Query: 376 DES---ENTYERISLTLDKITNHITYLNTQINETQ-KNDNAQ-LLWEAKKQIADLTEQNI 430
+ E + + + ++ T L ++ + Q + DN LL ++ + + LT+
Sbjct: 1245 HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS 1304
Query: 431 ILKERLSQ----LETENKE---LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
L+ +L L+ EN++ L +++ V L++
Sbjct: 1305 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHA 1364
Query: 484 EIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
++ DMK K+ + E ++V ++ QK+L+
Sbjct: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLE 1395
Score = 47.6 bits (108), Expect = 1e-04
Identities = 93/504 (18%), Positives = 200/504 (39%), Gaps = 35/504 (6%)
Query: 25 RLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKL 84
++ E +I +L+ L+ +K AE + ++ + L E
Sbjct: 1105 KIRELESQISELQEDLESERASRNK--AEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+ E + N LKK E+ A EA +E Q H+ V + E ++ V L ++L
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 145 E----EVALEIDL---KKNSITKDNISIKTLLDKLITK-NETD---------INELRNSI 187
E E+A E+ + K ++ L +L K NE + + +L+ +
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXX---XXXXXXX 244
+ + S+ ++ + KL + +A++ Q +Q+ +LL+ EN+ L
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDF-SALESQ--LQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN---FKQEIDMLNEKLICDRREFN 301
++ NLE+ L +++++K+K E+ + + + KL D +
Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATL-HAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLS 1398
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
+ +EK L K + ++EL++ L H + + E K + + + I+
Sbjct: 1399 QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ-KKFDQLLAEEKTIS 1457
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKITN---HITYLNTQINETQKNDNAQLLWEA 418
+ + + E E ++ L++ + LN Q T+ D +
Sbjct: 1458 AKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQF-RTEMEDLMSSKDDV 1516
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXX 478
K + +L + L++++ +++T+ +EL E+Q + + +NL+
Sbjct: 1517 GKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGR 1576
Query: 479 XXXSNE-IEDMKTKVMEWKSQFED 501
S E + + +V E +++ ED
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELED 1600
Score = 46.4 bits (105), Expect = 2e-04
Identities = 55/255 (21%), Positives = 110/255 (43%), Gaps = 24/255 (9%)
Query: 269 EEKLSEIKEKDENFKQ---EIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
EE L++ KE ++ K E+ L E+L R + QE++ L +++ K L
Sbjct: 1662 EEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAL 1721
Query: 326 EEK---QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
EEK + ++ L E+L + + N+ +LI + K + + D +I+ L+ E +N
Sbjct: 1722 EEKRRLEARIAQLEEELEEEQGNT-ELINDRLKK-ANLQID-QINTDLNLERSHAQKN-- 1776
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
E L++ + ++ T K+ + + +IA L E QL+ E
Sbjct: 1777 ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE----------QLDNE 1826
Query: 443 NKELLIEIQTVRGSN---EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQF 499
KE + VR + ++V L + D S ++ +K ++ E + +
Sbjct: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
Query: 500 EDLDDVMKQQQKELK 514
+ + ++ Q+EL+
Sbjct: 1887 QRANASRRKLQRELE 1901
Score = 45.6 bits (103), Expect = 4e-04
Identities = 79/465 (16%), Positives = 183/465 (39%), Gaps = 41/465 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L E L N +K D ELEALK E ++ E+ + +N L
Sbjct: 1116 LQEDLESERASRNKAEKQKRDLGEELEALKTE-LEDTLDSTAAQQELRSKREQEVNILKK 1174
Query: 140 GFES---LEEVALEIDLKKNSITKDNIS--------IKTLLDKLITKNETDINELRNSIK 188
E E ++ +K+S + ++ +K L+K E + EL N +K
Sbjct: 1175 TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVK 1234
Query: 189 YLESVKSEYNTANEKLFEQLNNAVDKQNC-------IQEEVDLLKIENQNLLQXXXXXXX 241
L K + +K+ QL K N + ++V L++E N+
Sbjct: 1235 VLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDS 1294
Query: 242 XXXXXXXXXXARDKFIANLEEM------KTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC 295
A + + + +E+ + + + KL +++++ +F+++++ E
Sbjct: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEA--- 1351
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+ + + + ++D+ KK+ + LE +E L + L + + ++
Sbjct: 1352 -KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA-AYD 1409
Query: 356 KVSQIASDFKIS-NQLSCELDDESENT--YERISLTLDKITNHITYLNTQINETQKNDNA 412
K+ + + + + L +LD + ++ E+ D++ ++ + E + A
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 1469
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
+ + K ++ L E+ ++LE NK+ E++ + S ++V ++ +
Sbjct: 1470 EAREKETKALS-LARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 473 XXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
++E+MKT++ E + + + +D + + L+ K
Sbjct: 1529 AL-------EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMK 1566
Score = 44.0 bits (99), Expect = 0.001
Identities = 41/215 (19%), Positives = 94/215 (43%), Gaps = 7/215 (3%)
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
RD+ A E +T + L+ E+ K E++ LN++ + + + + +
Sbjct: 1464 RDRAEAEAREKETKALS--LARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSC 372
+L K E+++EE + QL L ++L TE+ +L N+ +Q D + ++ S
Sbjct: 1522 ELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQS- 1580
Query: 373 ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL 432
+++ + ++ ++ + + + +K + EA A+ I
Sbjct: 1581 --EEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAI- 1637
Query: 433 KERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS 467
++L +L+ + K+ + E+ R S EE+ K++
Sbjct: 1638 -KQLRKLQAQMKDCMRELDDTRASREEILAQAKEN 1671
Score = 43.2 bits (97), Expect = 0.002
Identities = 54/257 (21%), Positives = 115/257 (44%), Gaps = 20/257 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+ K ++L E E++E+ +Q++ + EK+ + + + ++E+ I+L D + K+ K
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQL--EKVTTEAKL--KKLEEEQIILEDQNCKLAK 992
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
++ LE++ + T L + E S K + + NK + +D + +L E E
Sbjct: 993 EKKLLEDRIAEFT---TNLTEEEEKS-KSLAKLKNKHEAMITD--LEERLRRE-----EK 1041
Query: 381 TYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
+ + T K+ T L+ QI E Q AQ+ E K Q+A E+ R+ +
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQ----AQIA-ELKMQLAKKEEELQAALARVEEEA 1096
Query: 441 TENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
+ L +I+ + E+ +L+ E+E +KT++ +
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
Query: 501 DLDDVMKQQQKELKLGK 517
++ ++++E+ + K
Sbjct: 1157 AQQELRSKREQEVNILK 1173
Score = 39.9 bits (89), Expect = 0.021
Identities = 49/282 (17%), Positives = 122/282 (43%), Gaps = 32/282 (11%)
Query: 261 EEMKTMLVEEKLSEIKEKD---ENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---- 313
+E + M EE+L +++EK EN E++ L +L+ ++ + E +Q + L ++
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 314 ----------LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----- 358
L + + E +EE++E+ HL + + N +L E + + S
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 359 ---QIASDFKIS--NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQ-----K 408
++ ++ K+ + L+D++ + L D+I T L + +++ K
Sbjct: 963 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 1022
Query: 409 NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
N + ++ + ++++ +Q L++ +LE ++ +L +I ++ E+ + L
Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQ 510
+ + K+ E +SQ +L + ++ ++
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Score = 32.3 bits (70), Expect = 4.2
Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
+V++ E E+ K+E+L + E+ EN +L E + +A ++ QL E +
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAEN---RLTEMETLQSQLMAEKLQLQEQLQAETEL 895
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
+E R LT K + + ++ + Q L KK++ +QNI L+E+
Sbjct: 896 CAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKM----QQNIQELEEQ 951
Query: 436 LSQLETENKELLIE 449
L + E+ ++L +E
Sbjct: 952 LEEEESARQKLQLE 965
>M81105-1|AAA59888.1| 1337|Homo sapiens cellular myosin heavy chain
protein.
Length = 1337
Score = 50.0 bits (114), Expect = 2e-05
Identities = 69/354 (19%), Positives = 144/354 (40%), Gaps = 23/354 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLL--- 233
+ + +++ +I+ LE E +A +KL + K ++EE +L+ +N L
Sbjct: 935 QAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEK 994
Query: 234 QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL 293
+ + K +A L+ ++ + L E ++E +QE++ KL
Sbjct: 995 KLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD-LEERLRREEKQRQELEKTRRKL 1053
Query: 294 ICDRREFNETMQEKNILLSDLSKKVNKTEREL-------EEKQEQLTHLMEQLNDTENNS 346
D + ++ + E +++L ++ K E EL EE+ Q ++++ + E+
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 347 YKLIENM------FNKVSQIASDF-KISNQLSCELDDESENTYERISLTLDKITNHITYL 399
+L E++ NK + D + L EL+D ++T + L K + L
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR-SKREQEVNIL 1172
Query: 400 NTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
+ E K AQ + E +++ + E+ L E+L Q + L QT+ E
Sbjct: 1173 KKTLEEEAKTHEAQ-IQEMRQKHSQAVEE---LAEQLEQTKRVKANLEKAKQTLENERGE 1228
Query: 460 VTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
+ +K ++++++ K E + +L D + + Q EL
Sbjct: 1229 LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Score = 43.2 bits (97), Expect = 0.002
Identities = 54/257 (21%), Positives = 115/257 (44%), Gaps = 20/257 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+ K ++L E E++E+ +Q++ + EK+ + + + ++E+ I+L D + K+ K
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQL--EKVTTEAKL--KKLEEEQIILEDQNCKLAK 992
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
++ LE++ + T L + E S K + + NK + +D + +L E E
Sbjct: 993 EKKLLEDRIAEFT---TNLTEEEEKS-KSLAKLKNKHEAMITD--LEERLRRE-----EK 1041
Query: 381 TYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
+ + T K+ T L+ QI E Q AQ+ E K Q+A E+ R+ +
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQ----AQIA-ELKMQLAKKEEELQAALARVEEEA 1096
Query: 441 TENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
+ L +I+ + E+ +L+ E+E +KT++ +
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
Query: 501 DLDDVMKQQQKELKLGK 517
++ ++++E+ + K
Sbjct: 1157 AQQELRSKREQEVNILK 1173
Score = 40.3 bits (90), Expect = 0.016
Identities = 51/267 (19%), Positives = 113/267 (42%), Gaps = 22/267 (8%)
Query: 157 SITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQN 216
++T++ K+L KL K+E I +L ++ E + E KL + D+
Sbjct: 1007 NLTEEEEKSKSLA-KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 217 CIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIK 276
+Q ++ LK++ + K I LE + L E+ SE
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 277 EKDENFKQEIDMLNEKLICDRREFNETM--------------QEKNILLSDLSKKVNKTE 322
+++ KQ+ D L E+L + E +T+ QE NIL L ++ E
Sbjct: 1126 SRNKAEKQKRD-LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD-FKISNQLSCELDDESENT 381
+++E +++ + +E+L + + ++ N+ + ++ +++N++ L + ++
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSE 1244
Query: 382 YERISLTLDKITNHITYLNTQINETQK 408
++R K+ + L + NE ++
Sbjct: 1245 HKR-----KKVEAQLQELQVKFNEGER 1266
Score = 39.9 bits (89), Expect = 0.021
Identities = 49/282 (17%), Positives = 122/282 (43%), Gaps = 32/282 (11%)
Query: 261 EEMKTMLVEEKLSEIKEKD---ENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---- 313
+E + M EE+L +++EK EN E++ L +L+ ++ + E +Q + L ++
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 314 ----------LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----- 358
L + + E +EE++E+ HL + + N +L E + + S
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 359 ---QIASDFKIS--NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQ-----K 408
++ ++ K+ + L+D++ + L D+I T L + +++ K
Sbjct: 963 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 1022
Query: 409 NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
N + ++ + ++++ +Q L++ +LE ++ +L +I ++ E+ + L
Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQ 510
+ + K+ E +SQ +L + ++ ++
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Score = 32.7 bits (71), Expect = 3.2
Identities = 42/186 (22%), Positives = 73/186 (39%), Gaps = 6/186 (3%)
Query: 25 RLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKL 84
++ E +I +L+ L+ +K AE + ++ + L E
Sbjct: 1105 KIRELESQISELQEDLESERASRNK--AEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+ E + N LKK E+ A EA +E Q H+ V + E ++ V L ++L
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKL 204
E E+ N + K + K + K E + EL+ E V++E KL
Sbjct: 1223 ENERGEL---ANEV-KVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKL 1278
Query: 205 FEQLNN 210
+L+N
Sbjct: 1279 QVELDN 1284
Score = 32.3 bits (70), Expect = 4.2
Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
+V++ E E+ K+E+L + E+ EN +L E + +A ++ QL E +
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAEN---RLTEMETLQSQLMAEKLQLQEQLQAETEL 895
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
+E R LT K + + ++ + Q L KK++ +QNI L+E+
Sbjct: 896 CAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKM----QQNIQELEEQ 951
Query: 436 LSQLETENKELLIE 449
L + E+ ++L +E
Sbjct: 952 LEEEESARQKLQLE 965
>L06148-1|AAA35921.1| 579|Homo sapiens golgin-165 protein.
Length = 579
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/289 (17%), Positives = 131/289 (45%), Gaps = 16/289 (5%)
Query: 95 KKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLK 154
K L E E+ AL + ++ V+ + + + + ES +++ALE++ +
Sbjct: 289 KTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHE 348
Query: 155 KNSIT---KDNISIK---TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQL 208
K +T + N +++ ++L+ + K E D+ +L ++ + K E + + L + L
Sbjct: 349 KGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQAL 408
Query: 209 NNAVDKQ----NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE-EM 263
+++K+ N ++E+V K+E + + A++ + L+ E
Sbjct: 409 QASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEA 468
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK---NILLSDLSKKVNK 320
+ + E + ++ F+ E+ +L +++ +E + ++ N + +L +V++
Sbjct: 469 DDLQIRE--GKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQ 526
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
ERE++ ++QL +Q +L++N+ +++ D ++ +
Sbjct: 527 KEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQK 575
Score = 35.1 bits (77), Expect = 0.60
Identities = 43/206 (20%), Positives = 90/206 (43%), Gaps = 19/206 (9%)
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
K+E+D +L E +ET+++ L+ S +V ++E ++Q+ + EQ
Sbjct: 20 KEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQ 79
Query: 343 E----------NNSYKLIENMFNKVSQIASDFKISNQLSCELDDE---SENTYERISLTL 389
+ + +LI + ++ S+ K Q ++ E +E R+ +
Sbjct: 80 KVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREV 139
Query: 390 DKITNHITYLNTQINETQKN-----DNAQLLWEAKKQIADLTEQNIILKERLSQLETENK 444
++ H+ L + QK + Q L K+Q+ +TE N LK+++ +L+ E +
Sbjct: 140 AQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEAR 199
Query: 445 ELLIE-IQTVRGSNEEVTLNLKDSST 469
+ + E Q +R ++T K+ T
Sbjct: 200 KAITEQKQKMRRLGSDLTSAQKEMKT 225
Score = 32.3 bits (70), Expect = 4.2
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
EL + LE E + EKL E+L + +Q+E LK + Q + +
Sbjct: 22 ELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKV 81
Query: 242 XXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFN 301
++D+ I+ L+ + L + +L E++++ E +L RE
Sbjct: 82 MVEAYRRDATSKDQLISELKATRKRL-DSELKELRQELMQVHGEKRTAEAELSRLHREVA 140
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL 335
+ Q ++DL + ++E +E + L L
Sbjct: 141 QVRQH----MADLEGHLQSAQKERDEMETHLQSL 170
>D63997-1|BAA23661.1| 1530|Homo sapiens GCP170 protein.
Length = 1530
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/289 (17%), Positives = 131/289 (45%), Gaps = 16/289 (5%)
Query: 95 KKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLK 154
K L E E+ AL + ++ V+ + + + + ES +++ALE++ +
Sbjct: 1058 KTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHE 1117
Query: 155 KNSIT---KDNISIK---TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQL 208
K +T + N +++ ++L+ + K E D+ +L ++ + K E + + L + L
Sbjct: 1118 KGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQAL 1177
Query: 209 NNAVDKQ----NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE-EM 263
+++K+ N ++E+V K+E + + A++ + L+ E
Sbjct: 1178 QASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEA 1237
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK---NILLSDLSKKVNK 320
+ + E + ++ F+ E+ +L +++ +E + ++ N + +L +V++
Sbjct: 1238 DDLQIRE--GKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQ 1295
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
ERE++ ++QL +Q +L++N+ +++ D ++ +
Sbjct: 1296 KEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQK 1344
Score = 42.7 bits (96), Expect = 0.003
Identities = 47/236 (19%), Positives = 101/236 (42%), Gaps = 11/236 (4%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNI 163
+LEAL++E++ + + + E + S + ++ L ++ L+ E+ + S +D I
Sbjct: 711 QLEALQQEHLDL-MKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAAS-REDTI 768
Query: 164 SI----KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQ 219
+ K +L+ + ++ EL + LE E + EKL E+L + +Q
Sbjct: 769 CLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQ 828
Query: 220 EEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD 279
+E LK + Q + + ++D+ I+ L+ + L + +L E++++
Sbjct: 829 QETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRL-DSELKELRQEL 887
Query: 280 ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL 335
E +L RE + Q ++DL + ++E +E + L L
Sbjct: 888 MQVHGEKRTAEAELSRLHREVAQVRQH----MADLEGHLQSAQKERDEMETHLQSL 939
Score = 36.7 bits (81), Expect = 0.20
Identities = 49/233 (21%), Positives = 102/233 (43%), Gaps = 21/233 (9%)
Query: 258 ANLEEMKTMLVEEK--LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
A+ E+ +L EK L + ++ K+E+D +L E +ET+++ L+ S
Sbjct: 762 ASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKS 821
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTE----------NNSYKLIENMFNKVSQIASDFK 365
+V ++E ++Q+ + EQ + + +LI + ++ S+ K
Sbjct: 822 GQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELK 881
Query: 366 ISNQLSCELDDE---SENTYERISLTLDKITNHITYLNTQINETQKN-----DNAQLLWE 417
Q ++ E +E R+ + ++ H+ L + QK + Q L
Sbjct: 882 ELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQF 941
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIE-IQTVRGSNEEVTLNLKDSST 469
K+Q+ +TE N LK+++ +L+ E ++ + E Q +R ++T K+ T
Sbjct: 942 DKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKT 994
>CR456526-1|CAG30412.1| 1960|Homo sapiens MYH9 protein.
Length = 1960
Score = 50.0 bits (114), Expect = 2e-05
Identities = 69/354 (19%), Positives = 144/354 (40%), Gaps = 23/354 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLL--- 233
+ + +++ +I+ LE E +A +KL + K ++EE +L+ +N L
Sbjct: 935 QAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEK 994
Query: 234 QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL 293
+ + K +A L+ ++ + L E ++E +QE++ KL
Sbjct: 995 KLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD-LEERLRREEKQRQELEKTRRKL 1053
Query: 294 ICDRREFNETMQEKNILLSDLSKKVNKTEREL-------EEKQEQLTHLMEQLNDTENNS 346
D + ++ + E +++L ++ K E EL EE+ Q ++++ + E+
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 347 YKLIENM------FNKVSQIASDF-KISNQLSCELDDESENTYERISLTLDKITNHITYL 399
+L E++ NK + D + L EL+D ++T + L K + L
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR-SKREQEVNIL 1172
Query: 400 NTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
+ E K AQ + E +++ + E+ L E+L Q + L QT+ E
Sbjct: 1173 KKTLEEEAKTHEAQ-IQEMRQKHSQAVEE---LAEQLEQTKRVKANLEKAKQTLENERGE 1228
Query: 460 VTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
+ +K ++++++ K E + +L D + + Q EL
Sbjct: 1229 LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Score = 49.2 bits (112), Expect = 3e-05
Identities = 78/391 (19%), Positives = 160/391 (40%), Gaps = 35/391 (8%)
Query: 157 SITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQN 216
++T++ K+L KL K+E I +L ++ E + E KL + D+
Sbjct: 1007 NLTEEEEKSKSLA-KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 217 CIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIK 276
+Q ++ LK++ + K I LE + L E+ SE
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 277 EKDENFKQEIDMLNEKLICDRREFNETM--------------QEKNILLSDLSKKVNKTE 322
+++ KQ+ D L E+L + E +T+ QE NIL L ++ E
Sbjct: 1126 SRNKAEKQKRD-LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 323 RELEEKQ-------EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+++E + E+L +EQ + N K + + N+ ++A++ K+ Q + +
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSE 1244
Query: 376 DES---ENTYERISLTLDKITNHITYLNTQINETQ-KNDNAQ-LLWEAKKQIADLTEQNI 430
+ E + + + ++ T L ++ + Q + DN LL ++ + + LT+
Sbjct: 1245 HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS 1304
Query: 431 ILKERLSQ----LETENKE---LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
L+ +L L+ EN++ L +++ V L++
Sbjct: 1305 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHA 1364
Query: 484 EIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
++ DMK K+ + E ++V ++ QK+L+
Sbjct: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLE 1395
Score = 47.6 bits (108), Expect = 1e-04
Identities = 93/504 (18%), Positives = 200/504 (39%), Gaps = 35/504 (6%)
Query: 25 RLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKL 84
++ E +I +L+ L+ +K AE + ++ + L E
Sbjct: 1105 KIRELESQISELQEDLESERASRNK--AEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+ E + N LKK E+ A EA +E Q H+ V + E ++ V L ++L
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 145 E----EVALEIDL---KKNSITKDNISIKTLLDKLITK-NETD---------INELRNSI 187
E E+A E+ + K ++ L +L K NE + + +L+ +
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXX---XXXXXXX 244
+ + S+ ++ + KL + +A++ Q +Q+ +LL+ EN+ L
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDF-SALESQ--LQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN---FKQEIDMLNEKLICDRREFN 301
++ NLE+ L +++++K+K E+ + + + KL D +
Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATL-HAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLS 1398
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
+ +EK L K + ++EL++ L H + + E K + + + I+
Sbjct: 1399 QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ-KKFDQLLAEEKTIS 1457
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKITN---HITYLNTQINETQKNDNAQLLWEA 418
+ + + E E ++ L++ + LN Q T+ D +
Sbjct: 1458 AKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQF-RTEMEDLMSSKDDV 1516
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXX 478
K + +L + L++++ +++T+ +EL E+Q + + +NL+
Sbjct: 1517 GKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGR 1576
Query: 479 XXXSNE-IEDMKTKVMEWKSQFED 501
S E + + +V E +++ ED
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELED 1600
Score = 46.4 bits (105), Expect = 2e-04
Identities = 55/255 (21%), Positives = 110/255 (43%), Gaps = 24/255 (9%)
Query: 269 EEKLSEIKEKDENFKQ---EIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
EE L++ KE ++ K E+ L E+L R + QE++ L +++ K L
Sbjct: 1662 EEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAL 1721
Query: 326 EEK---QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
EEK + ++ L E+L + + N+ +LI + K + + D +I+ L+ E +N
Sbjct: 1722 EEKRRLEARIAQLEEELEEEQGNT-ELINDRLKK-ANLQID-QINTDLNLERSHAQKN-- 1776
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
E L++ + ++ T K+ + + +IA L E QL+ E
Sbjct: 1777 ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE----------QLDNE 1826
Query: 443 NKELLIEIQTVRGSN---EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQF 499
KE + VR + ++V L + D S ++ +K ++ E + +
Sbjct: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
Query: 500 EDLDDVMKQQQKELK 514
+ + ++ Q+EL+
Sbjct: 1887 QRANASRRKLQRELE 1901
Score = 45.6 bits (103), Expect = 4e-04
Identities = 79/465 (16%), Positives = 183/465 (39%), Gaps = 41/465 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L E L N +K D ELEALK E ++ E+ + +N L
Sbjct: 1116 LQEDLESERASRNKAEKQKRDLGEELEALKTE-LEDTLDSTAAQQELRSKREQEVNILKK 1174
Query: 140 GFES---LEEVALEIDLKKNSITKDNIS--------IKTLLDKLITKNETDINELRNSIK 188
E E ++ +K+S + ++ +K L+K E + EL N +K
Sbjct: 1175 TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVK 1234
Query: 189 YLESVKSEYNTANEKLFEQLNNAVDKQNC-------IQEEVDLLKIENQNLLQXXXXXXX 241
L K + +K+ QL K N + ++V L++E N+
Sbjct: 1235 VLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDS 1294
Query: 242 XXXXXXXXXXARDKFIANLEEM------KTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC 295
A + + + +E+ + + + KL +++++ +F+++++ E
Sbjct: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEA--- 1351
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+ + + + ++D+ KK+ + LE +E L + L + + ++
Sbjct: 1352 -KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA-AYD 1409
Query: 356 KVSQIASDFKIS-NQLSCELDDESENT--YERISLTLDKITNHITYLNTQINETQKNDNA 412
K+ + + + + L +LD + ++ E+ D++ ++ + E + A
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 1469
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
+ + K ++ L E+ ++LE NK+ E++ + S ++V ++ +
Sbjct: 1470 EAREKETKALS-LARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 473 XXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
++E+MKT++ E + + + +D + + L+ K
Sbjct: 1529 AL-------EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMK 1566
Score = 44.0 bits (99), Expect = 0.001
Identities = 41/215 (19%), Positives = 94/215 (43%), Gaps = 7/215 (3%)
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
RD+ A E +T + L+ E+ K E++ LN++ + + + + +
Sbjct: 1464 RDRAEAEAREKETKALS--LARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSC 372
+L K E+++EE + QL L ++L TE+ +L N+ +Q D + ++ S
Sbjct: 1522 ELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQS- 1580
Query: 373 ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL 432
+++ + ++ ++ + + + +K + EA A+ I
Sbjct: 1581 --EEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAI- 1637
Query: 433 KERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS 467
++L +L+ + K+ + E+ R S EE+ K++
Sbjct: 1638 -KQLRKLQAQMKDCMRELDDTRASREEILAQAKEN 1671
Score = 43.2 bits (97), Expect = 0.002
Identities = 54/257 (21%), Positives = 115/257 (44%), Gaps = 20/257 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+ K ++L E E++E+ +Q++ + EK+ + + + ++E+ I+L D + K+ K
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQL--EKVTTEAKL--KKLEEEQIILEDQNCKLAK 992
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
++ LE++ + T L + E S K + + NK + +D + +L E E
Sbjct: 993 EKKLLEDRIAEFT---TNLTEEEEKS-KSLAKLKNKHEAMITD--LEERLRRE-----EK 1041
Query: 381 TYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
+ + T K+ T L+ QI E Q AQ+ E K Q+A E+ R+ +
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQ----AQIA-ELKMQLAKKEEELQAALARVEEEA 1096
Query: 441 TENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
+ L +I+ + E+ +L+ E+E +KT++ +
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
Query: 501 DLDDVMKQQQKELKLGK 517
++ ++++E+ + K
Sbjct: 1157 AQQELRSKREQEVNILK 1173
Score = 39.9 bits (89), Expect = 0.021
Identities = 49/282 (17%), Positives = 122/282 (43%), Gaps = 32/282 (11%)
Query: 261 EEMKTMLVEEKLSEIKEKD---ENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---- 313
+E + M EE+L +++EK EN E++ L +L+ ++ + E +Q + L ++
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 314 ----------LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----- 358
L + + E +EE++E+ HL + + N +L E + + S
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 359 ---QIASDFKIS--NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQ-----K 408
++ ++ K+ + L+D++ + L D+I T L + +++ K
Sbjct: 963 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 1022
Query: 409 NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
N + ++ + ++++ +Q L++ +LE ++ +L +I ++ E+ + L
Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQ 510
+ + K+ E +SQ +L + ++ ++
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Score = 32.3 bits (70), Expect = 4.2
Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
+V++ E E+ K+E+L + E+ EN +L E + +A ++ QL E +
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAEN---RLTEMETLQSQLMAEKLQLQEQLQAETEL 895
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
+E R LT K + + ++ + Q L KK++ +QNI L+E+
Sbjct: 896 CAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKM----QQNIQELEEQ 951
Query: 436 LSQLETENKELLIE 449
L + E+ ++L +E
Sbjct: 952 LEEEESARQKLQLE 965
>BC060037-1|AAH60037.1| 622|Homo sapiens KIAA1212 protein protein.
Length = 622
Score = 50.0 bits (114), Expect = 2e-05
Identities = 39/147 (26%), Positives = 68/147 (46%), Gaps = 5/147 (3%)
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
E+ Q ++ L+D K+ + +ELEEK EQL ++L E +L + N +S
Sbjct: 244 ESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQENMNLLSDAR 303
Query: 362 SDFKISNQLSC--ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAK 419
S ++L E + +S +++ + I + ++ E K DN Q+L E K
Sbjct: 304 SARMYRDELDALREKVVRVDKLESEVSRYKERL-HDIEFYKARVEEL-KEDN-QVLLETK 360
Query: 420 KQIADLTEQNIILKERLSQLETENKEL 446
+ D E ++L +LE EN +L
Sbjct: 361 TMLEDQLEGTRARSDKLHELEKENLQL 387
Score = 34.7 bits (76), Expect = 0.80
Identities = 71/393 (18%), Positives = 171/393 (43%), Gaps = 36/393 (9%)
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
+ + + D++ L ++ A L+ L E + H+ ++ + E D L + + ++
Sbjct: 176 MEVTDMSQEDIEPLLKNMALHLKRLIDERDE-HSETIIELSEERDGLHFLPHASSSAQSP 234
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
++ + ++ + K + +L + E +L + + LE ++ E ++
Sbjct: 235 CGSPGMKRTESRQHLSVELADAKAKIRRLRQELEEKTEQLLDCKQELEQMEIELKRLQQE 294
Query: 204 LFEQLNNAVDKQNCIQEEVDLL--KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN-- 259
L++A + ++E+D L K+ + L+ AR + +
Sbjct: 295 NMNLLSDARSAR-MYRDELDALREKVVRVDKLESEVSRYKERLHDIEFYKARVEELKEDN 353
Query: 260 --LEEMKTMLVEE---------KLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
L E KTML ++ KL E+++++ K ++ + + DR++ E M+E
Sbjct: 354 QVLLETKTMLEDQLEGTRARSDKLHELEKENLQLKAKLHDMEMERDMDRKKIEELMEENM 413
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISN 368
L +++ ++ L +EQ++ T S +++ ++V+++ S S
Sbjct: 414 TL--------EMAQKQSMDESLHLGWELEQISRTSELSEAPQKSLGHEVNELTS----SR 461
Query: 369 QLSCELDDES-ENTYERISLTLDKITNHITYLNTQINETQK-NDNAQLLWEAKKQIADLT 426
L E++++S T E + T+D + + + + E Q+ + ++L + +I
Sbjct: 462 LLKLEMENQSLTKTVEELRTTVDSVEGNASKILKMEKENQRLSKKVEIL---ENEIVQ-E 517
Query: 427 EQNIILKERLSQ-LETENKELLIEIQTVRGSNE 458
+Q++ + LS+ L E +L I+T+R ++E
Sbjct: 518 KQSLQNCQNLSKDLMKEKAQLEKTIETLRENSE 550
>BC049849-1|AAH49849.1| 1374|Homo sapiens Unknown (protein for
IMAGE:5563109) protein.
Length = 1374
Score = 50.0 bits (114), Expect = 2e-05
Identities = 69/354 (19%), Positives = 144/354 (40%), Gaps = 23/354 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLL--- 233
+ + +++ +I+ LE E +A +KL + K ++EE +L+ +N L
Sbjct: 935 QAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEK 994
Query: 234 QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL 293
+ + K +A L+ ++ + L E ++E +QE++ KL
Sbjct: 995 KLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD-LEERLRREEKQRQELEKTRRKL 1053
Query: 294 ICDRREFNETMQEKNILLSDLSKKVNKTEREL-------EEKQEQLTHLMEQLNDTENNS 346
D + ++ + E +++L ++ K E EL EE+ Q ++++ + E+
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 347 YKLIENM------FNKVSQIASDF-KISNQLSCELDDESENTYERISLTLDKITNHITYL 399
+L E++ NK + D + L EL+D ++T + L K + L
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR-SKREQEVNIL 1172
Query: 400 NTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
+ E K AQ + E +++ + E+ L E+L Q + L QT+ E
Sbjct: 1173 KKTLEEEAKTHEAQ-IQEMRQKHSQAVEE---LAEQLEQTKRVKANLEKAKQTLENERGE 1228
Query: 460 VTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
+ +K ++++++ K E + +L D + + Q EL
Sbjct: 1229 LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Score = 43.2 bits (97), Expect = 0.002
Identities = 54/257 (21%), Positives = 115/257 (44%), Gaps = 20/257 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+ K ++L E E++E+ +Q++ + EK+ + + + ++E+ I+L D + K+ K
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQL--EKVTTEAKL--KKLEEEQIILEDQNCKLAK 992
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
++ LE++ + T L + E S K + + NK + +D + +L E E
Sbjct: 993 EKKLLEDRIAEFT---TNLTEEEEKS-KSLAKLKNKHEAMITD--LEERLRRE-----EK 1041
Query: 381 TYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
+ + T K+ T L+ QI E Q AQ+ E K Q+A E+ R+ +
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQ----AQIA-ELKMQLAKKEEELQAALARVEEEA 1096
Query: 441 TENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
+ L +I+ + E+ +L+ E+E +KT++ +
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
Query: 501 DLDDVMKQQQKELKLGK 517
++ ++++E+ + K
Sbjct: 1157 AQQELRSKREQEVNILK 1173
Score = 40.7 bits (91), Expect = 0.012
Identities = 73/368 (19%), Positives = 147/368 (39%), Gaps = 35/368 (9%)
Query: 157 SITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQN 216
++T++ K+L KL K+E I +L ++ E + E KL + D+
Sbjct: 1007 NLTEEEEKSKSLA-KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 217 CIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIK 276
+Q ++ LK++ + K I LE + L E+ SE
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 277 EKDENFKQEIDMLNEKLICDRREFNETM--------------QEKNILLSDLSKKVNKTE 322
+++ KQ+ D L E+L + E +T+ QE NIL L ++ E
Sbjct: 1126 SRNKAEKQKRD-LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 323 RELEEKQ-------EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+++E + E+L +EQ + N K + + N+ ++A++ K+ Q + +
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSE 1244
Query: 376 DES---ENTYERISLTLDKITNHITYLNTQINETQ-KNDNAQ-LLWEAKKQIADLTEQNI 430
+ E + + + ++ T L ++ + Q + DN LL ++ + + LT+
Sbjct: 1245 HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS 1304
Query: 431 ILKERLSQ----LETENKE---LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
L+ +L L+ EN++ L +++ V L++
Sbjct: 1305 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHA 1364
Query: 484 EIEDMKTK 491
++ DMK K
Sbjct: 1365 QVADMKKK 1372
Score = 39.9 bits (89), Expect = 0.021
Identities = 49/282 (17%), Positives = 122/282 (43%), Gaps = 32/282 (11%)
Query: 261 EEMKTMLVEEKLSEIKEKD---ENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---- 313
+E + M EE+L +++EK EN E++ L +L+ ++ + E +Q + L ++
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 314 ----------LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----- 358
L + + E +EE++E+ HL + + N +L E + + S
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 359 ---QIASDFKIS--NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQ-----K 408
++ ++ K+ + L+D++ + L D+I T L + +++ K
Sbjct: 963 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 1022
Query: 409 NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
N + ++ + ++++ +Q L++ +LE ++ +L +I ++ E+ + L
Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQ 510
+ + K+ E +SQ +L + ++ ++
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Score = 32.7 bits (71), Expect = 3.2
Identities = 42/186 (22%), Positives = 73/186 (39%), Gaps = 6/186 (3%)
Query: 25 RLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKL 84
++ E +I +L+ L+ +K AE + ++ + L E
Sbjct: 1105 KIRELESQISELQEDLESERASRNK--AEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+ E + N LKK E+ A EA +E Q H+ V + E ++ V L ++L
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKL 204
E E+ N + K + K + K E + EL+ E V++E KL
Sbjct: 1223 ENERGEL---ANEV-KVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKL 1278
Query: 205 FEQLNN 210
+L+N
Sbjct: 1279 QVELDN 1284
Score = 32.3 bits (70), Expect = 4.2
Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
+V++ E E+ K+E+L + E+ EN +L E + +A ++ QL E +
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAEN---RLTEMETLQSQLMAEKLQLQEQLQAETEL 895
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
+E R LT K + + ++ + Q L KK++ +QNI L+E+
Sbjct: 896 CAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKM----QQNIQELEEQ 951
Query: 436 LSQLETENKELLIE 449
L + E+ ++L +E
Sbjct: 952 LEEEESARQKLQLE 965
>BC048203-1|AAH48203.1| 663|Homo sapiens Unknown (protein for
IMAGE:4139784) protein.
Length = 663
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/289 (17%), Positives = 131/289 (45%), Gaps = 16/289 (5%)
Query: 95 KKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLK 154
K L E E+ AL + ++ V+ + + + + ES +++ALE++ +
Sbjct: 270 KTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHE 329
Query: 155 KNSIT---KDNISIK---TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQL 208
K +T + N +++ ++L+ + K E D+ +L ++ + K E + + L + L
Sbjct: 330 KGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQAL 389
Query: 209 NNAVDKQ----NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE-EM 263
+++K+ N ++E+V K+E + + A++ + L+ E
Sbjct: 390 QASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEA 449
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK---NILLSDLSKKVNK 320
+ + E + ++ F+ E+ +L +++ +E + ++ N + +L +V++
Sbjct: 450 DDLQIRE--GKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQ 507
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
ERE++ ++QL +Q +L++N+ +++ D ++ +
Sbjct: 508 KEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQK 556
Score = 35.1 bits (77), Expect = 0.60
Identities = 43/206 (20%), Positives = 90/206 (43%), Gaps = 19/206 (9%)
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
K+E+D +L E +ET+++ L+ S +V ++E ++Q+ + EQ
Sbjct: 1 KEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQ 60
Query: 343 E----------NNSYKLIENMFNKVSQIASDFKISNQLSCELDDE---SENTYERISLTL 389
+ + +LI + ++ S+ K Q ++ E +E R+ +
Sbjct: 61 KVMVEAYRRDATSKDQLISELKATRKRLDSELKELRQELMQVHGEKRTAEAELSRLHREV 120
Query: 390 DKITNHITYLNTQINETQKN-----DNAQLLWEAKKQIADLTEQNIILKERLSQLETENK 444
++ H+ L + QK + Q L K+Q+ +TE N LK+++ +L+ E +
Sbjct: 121 AQVRQHMADLEGHLQSAQKERDEMETHLQSLQFDKEQMVAVTEANEALKKQIEELQQEAR 180
Query: 445 ELLIE-IQTVRGSNEEVTLNLKDSST 469
+ + E Q +R ++T K+ T
Sbjct: 181 KAITEQKQKMRRLGSDLTSAQKEMKT 206
Score = 32.3 bits (70), Expect = 4.2
Identities = 32/154 (20%), Positives = 62/154 (40%), Gaps = 5/154 (3%)
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
EL + LE E + EKL E+L + +Q+E LK + Q + +
Sbjct: 3 ELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQQETAALKKQMQKIKEQFLQQKV 62
Query: 242 XXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFN 301
++D+ I+ L+ + L + +L E++++ E +L RE
Sbjct: 63 MVEAYRRDATSKDQLISELKATRKRL-DSELKELRQELMQVHGEKRTAEAELSRLHREVA 121
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL 335
+ Q ++DL + ++E +E + L L
Sbjct: 122 QVRQH----MADLEGHLQSAQKERDEMETHLQSL 151
>AL589649-3|CAH71820.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 50.0 bits (114), Expect = 2e-05
Identities = 87/380 (22%), Positives = 160/380 (42%), Gaps = 54/380 (14%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLT--EVINT- 136
+ KL E+ + L+ +E L+ N + ++ + E+ D + E N+
Sbjct: 317 MNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEEL-QELRDKIAKGECGNSS 375
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
L E+L + LE++ K ITK + L KL + E ELR ++ L+ SE
Sbjct: 376 LMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKL-QEEEHHSKELRLEVEKLQKRMSE 434
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIEN--QNLLQXXXXXXXXXXXXXXXXXARD 254
EKL E + + K C Q ++L K +N ++LL +
Sbjct: 435 L----EKLEEAFSKS--KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE 488
Query: 255 KF-------IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
K + L+ MLV+E+ + EK + ++++D LN+ ++ + + ++
Sbjct: 489 KAELSLKDDLTKLKSFTVMLVDER-KNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK- 546
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
L + SKK+ K + E+EEK LT ++L + ++ S+ + S
Sbjct: 547 ---LIEESKKLLKLKSEMEEKVYNLTRERDEL-----------------IGKLKSEEEKS 586
Query: 368 NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE 427
++LSC +D L K + I + +I + ++L +I +LT
Sbjct: 587 SELSCSVD------------LLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTL 634
Query: 428 QNIILKERLSQLETENKELL 447
+ LK+RL QLE +L+
Sbjct: 635 EIERLKKRLQQLEVVEGDLM 654
Score = 38.3 bits (85), Expect = 0.065
Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 14/172 (8%)
Query: 269 EEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEK 328
EEKL I K + +Q++ L F++ +E N L++ R+L K
Sbjct: 279 EEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESH----NRQLRLK 334
Query: 329 QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLT 388
LT +E+L +T N K E + +IA ++ L E+ EN +R+ L
Sbjct: 335 LVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEV----ENLRKRV-LE 389
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
++ IT +Q E +K L E + +L + L++R+S+LE
Sbjct: 390 MEGKDEEITKTESQCRELRKK-----LQEEEHHSKELRLEVEKLQKRMSELE 436
Score = 33.9 bits (74), Expect = 1.4
Identities = 53/325 (16%), Positives = 128/325 (39%), Gaps = 11/325 (3%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E L++ E++ + + +K S T L + K + +L N ++ ++S E +
Sbjct: 426 EKLQKRMSELEKLEEAFSKSK-SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 484
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
+L + + D ++ +L E +N+++ + ++
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 544
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
E K + +KL ++K + E + ++LI + E E + + L K+++
Sbjct: 545 E-KLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGI 603
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENT 381
E E + +L E+N K + ++ + ++ + +DE +
Sbjct: 604 EEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQL 663
Query: 382 YERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
++ DK +L+ Q+ E + Q+ + ++ Q L+ R E
Sbjct: 664 EQKFRTEQDK----ANFLSQQLEEIKH----QIAKNKAIEKGEVVSQEAELRHRFRLEEA 715
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKD 466
++++L E+Q ++ E+ +N +D
Sbjct: 716 KSRDLKAEVQALKEKIHEL-MNKED 739
>AL589649-1|CAH71818.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 50.0 bits (114), Expect = 2e-05
Identities = 87/380 (22%), Positives = 160/380 (42%), Gaps = 54/380 (14%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLT--EVINT- 136
+ KL E+ + L+ +E L+ N + ++ + E+ D + E N+
Sbjct: 218 MNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEEL-QELRDKIAKGECGNSS 276
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
L E+L + LE++ K ITK + L KL + E ELR ++ L+ SE
Sbjct: 277 LMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKL-QEEEHHSKELRLEVEKLQKRMSE 335
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIEN--QNLLQXXXXXXXXXXXXXXXXXARD 254
EKL E + + K C Q ++L K +N ++LL +
Sbjct: 336 L----EKLEEAFSKS--KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE 389
Query: 255 KF-------IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
K + L+ MLV+E+ + EK + ++++D LN+ ++ + + ++
Sbjct: 390 KAELSLKDDLTKLKSFTVMLVDER-KNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK- 447
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
L + SKK+ K + E+EEK LT ++L + ++ S+ + S
Sbjct: 448 ---LIEESKKLLKLKSEMEEKVYNLTRERDEL-----------------IGKLKSEEEKS 487
Query: 368 NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE 427
++LSC +D L K + I + +I + ++L +I +LT
Sbjct: 488 SELSCSVD------------LLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTL 535
Query: 428 QNIILKERLSQLETENKELL 447
+ LK+RL QLE +L+
Sbjct: 536 EIERLKKRLQQLEVVEGDLM 555
Score = 38.3 bits (85), Expect = 0.065
Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 14/172 (8%)
Query: 269 EEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEK 328
EEKL I K + +Q++ L F++ +E N L++ R+L K
Sbjct: 180 EEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESH----NRQLRLK 235
Query: 329 QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLT 388
LT +E+L +T N K E + +IA ++ L E+ EN +R+ L
Sbjct: 236 LVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEV----ENLRKRV-LE 290
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
++ IT +Q E +K L E + +L + L++R+S+LE
Sbjct: 291 MEGKDEEITKTESQCRELRKK-----LQEEEHHSKELRLEVEKLQKRMSELE 337
Score = 33.9 bits (74), Expect = 1.4
Identities = 53/325 (16%), Positives = 128/325 (39%), Gaps = 11/325 (3%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E L++ E++ + + +K S T L + K + +L N ++ ++S E +
Sbjct: 327 EKLQKRMSELEKLEEAFSKSK-SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 385
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
+L + + D ++ +L E +N+++ + ++
Sbjct: 386 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 445
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
E K + +KL ++K + E + ++LI + E E + + L K+++
Sbjct: 446 E-KLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGI 504
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENT 381
E E + +L E+N K + ++ + ++ + +DE +
Sbjct: 505 EEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQL 564
Query: 382 YERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
++ DK +L+ Q+ E + Q+ + ++ Q L+ R E
Sbjct: 565 EQKFRTEQDK----ANFLSQQLEEIKH----QIAKNKAIEKGEVVSQEAELRHRFRLEEA 616
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKD 466
++++L E+Q ++ E+ +N +D
Sbjct: 617 KSRDLKAEVQALKEKIHEL-MNKED 640
>AL445465-2|CAH73615.1| 1213|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1213
Score = 50.0 bits (114), Expect = 2e-05
Identities = 87/380 (22%), Positives = 160/380 (42%), Gaps = 54/380 (14%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLT--EVINT- 136
+ KL E+ + L+ +E L+ N + ++ + E+ D + E N+
Sbjct: 317 MNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEEL-QELRDKIAKGECGNSS 375
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
L E+L + LE++ K ITK + L KL + E ELR ++ L+ SE
Sbjct: 376 LMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKL-QEEEHHSKELRLEVEKLQKRMSE 434
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIEN--QNLLQXXXXXXXXXXXXXXXXXARD 254
EKL E + + K C Q ++L K +N ++LL +
Sbjct: 435 L----EKLEEAFSKS--KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE 488
Query: 255 KF-------IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
K + L+ MLV+E+ + EK + ++++D LN+ ++ + + ++
Sbjct: 489 KAELSLKDDLTKLKSFTVMLVDER-KNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK- 546
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
L + SKK+ K + E+EEK LT ++L + ++ S+ + S
Sbjct: 547 ---LIEESKKLLKLKSEMEEKVYNLTRERDEL-----------------IGKLKSEEEKS 586
Query: 368 NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE 427
++LSC +D L K + I + +I + ++L +I +LT
Sbjct: 587 SELSCSVD------------LLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTL 634
Query: 428 QNIILKERLSQLETENKELL 447
+ LK+RL QLE +L+
Sbjct: 635 EIERLKKRLQQLEVVEGDLM 654
Score = 38.3 bits (85), Expect = 0.065
Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 14/172 (8%)
Query: 269 EEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEK 328
EEKL I K + +Q++ L F++ +E N L++ R+L K
Sbjct: 279 EEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESH----NRQLRLK 334
Query: 329 QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLT 388
LT +E+L +T N K E + +IA ++ L E+ EN +R+ L
Sbjct: 335 LVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEV----ENLRKRV-LE 389
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
++ IT +Q E +K L E + +L + L++R+S+LE
Sbjct: 390 MEGKDEEITKTESQCRELRKK-----LQEEEHHSKELRLEVEKLQKRMSELE 436
Score = 33.9 bits (74), Expect = 1.4
Identities = 53/325 (16%), Positives = 128/325 (39%), Gaps = 11/325 (3%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E L++ E++ + + +K S T L + K + +L N ++ ++S E +
Sbjct: 426 EKLQKRMSELEKLEEAFSKSK-SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 484
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
+L + + D ++ +L E +N+++ + ++
Sbjct: 485 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 544
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
E K + +KL ++K + E + ++LI + E E + + L K+++
Sbjct: 545 E-KLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGI 603
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENT 381
E E + +L E+N K + ++ + ++ + +DE +
Sbjct: 604 EEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQL 663
Query: 382 YERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
++ DK +L+ Q+ E + Q+ + ++ Q L+ R E
Sbjct: 664 EQKFRTEQDK----ANFLSQQLEEIKH----QIAKNKAIEKGEVVSQEAELRHRFRLEEA 715
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKD 466
++++L E+Q ++ E+ +N +D
Sbjct: 716 KSRDLKAEVQALKEKIHEL-MNKED 739
>AL445465-1|CAH73614.1| 1114|Homo sapiens filamin A interacting
protein 1 protein.
Length = 1114
Score = 50.0 bits (114), Expect = 2e-05
Identities = 87/380 (22%), Positives = 160/380 (42%), Gaps = 54/380 (14%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLT--EVINT- 136
+ KL E+ + L+ +E L+ N + ++ + E+ D + E N+
Sbjct: 218 MNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEEL-QELRDKIAKGECGNSS 276
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
L E+L + LE++ K ITK + L KL + E ELR ++ L+ SE
Sbjct: 277 LMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKL-QEEEHHSKELRLEVEKLQKRMSE 335
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIEN--QNLLQXXXXXXXXXXXXXXXXXARD 254
EKL E + + K C Q ++L K +N ++LL +
Sbjct: 336 L----EKLEEAFSKS--KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE 389
Query: 255 KF-------IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
K + L+ MLV+E+ + EK + ++++D LN+ ++ + + ++
Sbjct: 390 KAELSLKDDLTKLKSFTVMLVDER-KNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK- 447
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
L + SKK+ K + E+EEK LT ++L + ++ S+ + S
Sbjct: 448 ---LIEESKKLLKLKSEMEEKVYNLTRERDEL-----------------IGKLKSEEEKS 487
Query: 368 NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE 427
++LSC +D L K + I + +I + ++L +I +LT
Sbjct: 488 SELSCSVD------------LLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTL 535
Query: 428 QNIILKERLSQLETENKELL 447
+ LK+RL QLE +L+
Sbjct: 536 EIERLKKRLQQLEVVEGDLM 555
Score = 38.3 bits (85), Expect = 0.065
Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 14/172 (8%)
Query: 269 EEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEK 328
EEKL I K + +Q++ L F++ +E N L++ R+L K
Sbjct: 180 EEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESH----NRQLRLK 235
Query: 329 QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLT 388
LT +E+L +T N K E + +IA ++ L E+ EN +R+ L
Sbjct: 236 LVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEV----ENLRKRV-LE 290
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
++ IT +Q E +K L E + +L + L++R+S+LE
Sbjct: 291 MEGKDEEITKTESQCRELRKK-----LQEEEHHSKELRLEVEKLQKRMSELE 337
Score = 33.9 bits (74), Expect = 1.4
Identities = 53/325 (16%), Positives = 128/325 (39%), Gaps = 11/325 (3%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E L++ E++ + + +K S T L + K + +L N ++ ++S E +
Sbjct: 327 EKLQKRMSELEKLEEAFSKSK-SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 385
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
+L + + D ++ +L E +N+++ + ++
Sbjct: 386 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 445
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
E K + +KL ++K + E + ++LI + E E + + L K+++
Sbjct: 446 E-KLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGI 504
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENT 381
E E + +L E+N K + ++ + ++ + +DE +
Sbjct: 505 EEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQL 564
Query: 382 YERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
++ DK +L+ Q+ E + Q+ + ++ Q L+ R E
Sbjct: 565 EQKFRTEQDK----ANFLSQQLEEIKH----QIAKNKAIEKGEVVSQEAELRHRFRLEEA 616
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKD 466
++++L E+Q ++ E+ +N +D
Sbjct: 617 KSRDLKAEVQALKEKIHEL-MNKED 640
>AL031283-6|CAI21428.1| 692|Homo sapiens forkhead-associated (FHA)
phosphopeptide binding domain 1 protein.
Length = 692
Score = 50.0 bits (114), Expect = 2e-05
Identities = 49/279 (17%), Positives = 123/279 (44%), Gaps = 7/279 (2%)
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE-NQNLLQXXXXXX 240
+LR + E + E EKL ++ +++ ++E + + + L +
Sbjct: 8 KLREHLAEKEKLNEERLEQEEKLKAKIRQLTEEKAALEEYITQERNRAKETLEEERKRMQ 67
Query: 241 XXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF 300
A K I + +EE+ + ++E +E ++ ++ + ++R+
Sbjct: 68 ELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQELEERLARQKEISESNIAYEKRKA 127
Query: 301 NETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
E M+++ + DL ++ K + ELE K+++ L +L+D + E K ++
Sbjct: 128 KEAMEKEKKKVQDLENRLTKQKEELELKEQKEDVLNNKLSDA---LAMVEETQKTKATES 184
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDK--ITNHITYLNTQINETQKNDNAQLLWEA 418
++ +L+ E E E T ++ + ++ + + E+Q++ + + E
Sbjct: 185 LKAESLALKLN-ETLAELETTKTKMIMVEERLILQQKMVKALQDEQESQRHGFEEEIMEY 243
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSN 457
K+QI + + L+E+L ++ +K++ EI T++ ++
Sbjct: 244 KEQIKQHAQTIVSLEEKLQKVTQHHKKIEGEIATLKDND 282
Score = 35.1 bits (77), Expect = 0.60
Identities = 50/227 (22%), Positives = 89/227 (39%), Gaps = 21/227 (9%)
Query: 267 LVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
L++EKL E + E +E EKL R+ E EK L ++++ N+ + LE
Sbjct: 4 LLQEKLREHLAEKEKLNEERLEQEEKLKAKIRQLTE---EKAALEEYITQERNRAKETLE 60
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERIS 386
E+++++ L L + K I N+V + + + Q EL+ ER++
Sbjct: 61 EERKRMQELESLLAQQKKALAKSITQEKNRVKEALEEEQTRVQ---ELE-------ERLA 110
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKEL 446
+ ++I Y + E + + KK++ DL + KE L E + L
Sbjct: 111 RQKEISESNIAYEKRKAKEAMEKE--------KKKVQDLENRLTKQKEELELKEQKEDVL 162
Query: 447 LIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
++ EE S E+E KTK++
Sbjct: 163 NNKLSDALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMI 209
>AK027705-1|BAB55310.1| 965|Homo sapiens protein ( Homo sapiens
cDNA FLJ14799 fis, clone NT2RP4001351, weakly similar to
Human ovarian cancer downregulated myosin heavy chain
homolog ).
Length = 965
Score = 50.0 bits (114), Expect = 2e-05
Identities = 87/380 (22%), Positives = 160/380 (42%), Gaps = 54/380 (14%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLT--EVINT- 136
+ KL E+ + L+ +E L+ N + ++ + E+ D + E N+
Sbjct: 69 MNAKLANQESHNRQLRLKLVGLTQRIEELEETNKNLQKAEEEL-QELRDKIAKGECGNSS 127
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
L E+L + LE++ K ITK + L KL + E ELR ++ L+ SE
Sbjct: 128 LMAEVENLRKRVLEMEGKDEEITKTESQCRELRKKL-QEEEHHSKELRLEVEKLQKRMSE 186
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIEN--QNLLQXXXXXXXXXXXXXXXXXARD 254
EKL E + + K C Q ++L K +N ++LL +
Sbjct: 187 L----EKLEEAFSKS--KSECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSESRLE 240
Query: 255 KF-------IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
K + L+ MLV+E+ + EK + ++++D LN+ ++ + + ++
Sbjct: 241 KAELSLKDDLTKLKSFTVMLVDER-KNMMEKIKQEERKVDGLNKNFKVEQGKVMDVTEK- 298
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
L + SKK+ K + E+EEK LT ++L + ++ S+ + S
Sbjct: 299 ---LIEESKKLLKLKSEMEEKVYNLTRERDEL-----------------IGKLKSEEEKS 338
Query: 368 NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTE 427
++LSC +D L K + I + +I + ++L +I +LT
Sbjct: 339 SELSCSVD------------LLKKRLDGIEEVEREITRGRSRKGSELTCPEDNKIKELTL 386
Query: 428 QNIILKERLSQLETENKELL 447
+ LK+RL QLE +L+
Sbjct: 387 EIERLKKRLQQLEVVEGDLM 406
Score = 38.3 bits (85), Expect = 0.065
Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 14/172 (8%)
Query: 269 EEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEK 328
EEKL I K + +Q++ L F++ +E N L++ R+L K
Sbjct: 31 EEKLKAITSKSKEDRQKLLKLEVDFEHKASRFSQEHEEMNAKLANQESH----NRQLRLK 86
Query: 329 QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLT 388
LT +E+L +T N K E + +IA ++ L E+ EN +R+ L
Sbjct: 87 LVGLTQRIEELEETNKNLQKAEEELQELRDKIAKGECGNSSLMAEV----ENLRKRV-LE 141
Query: 389 LDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
++ IT +Q E +K L E + +L + L++R+S+LE
Sbjct: 142 MEGKDEEITKTESQCRELRKK-----LQEEEHHSKELRLEVEKLQKRMSELE 188
Score = 31.1 bits (67), Expect = 9.8
Identities = 52/325 (16%), Positives = 127/325 (39%), Gaps = 11/325 (3%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E L++ E++ + + +K S T L + K + +L N ++ ++S E +
Sbjct: 178 EKLQKRMSELEKLEEAFSKSK-SECTQLHLNLEKEKNLTKDLLNELEVVKSRVKELECSE 236
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
+L + + D ++ +L E +N+++ + ++
Sbjct: 237 SRLEKAELSLKDDLTKLKSFTVMLVDERKNMMEKIKQEERKVDGLNKNFKVEQGKVMDVT 296
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
E K + +KL ++K + E + ++LI + E E + + L K+++
Sbjct: 297 E-KLIEESKKLLKLKSEMEEKVYNLTRERDELIGKLKSEEEKSSELSCSVDLLKKRLDGI 355
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENT 381
E E + +L E+N K + ++ + ++ + +DE +
Sbjct: 356 EEVEREITRGRSRKGSELTCPEDNKIKELTLEIERLKKRLQQLEVVEGDLMKTEDEYDQL 415
Query: 382 YERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLET 441
++ DK +L+ Q+ E + Q+ + ++ Q L+ R E
Sbjct: 416 EQKFRTEQDK----ANFLSQQLEEIKH----QIAKNKAIEKGEVVSQEAELRHRFRLEEA 467
Query: 442 ENKELLIEIQTVRGSNEEVTLNLKD 466
++++L +Q ++ E+ +N +D
Sbjct: 468 KSRDLKAGVQALKEKIHEL-MNKED 491
>AF432211-1|AAL99918.1| 460|Homo sapiens CLL-associated antigen
KW-11 protein.
Length = 460
Score = 50.0 bits (114), Expect = 2e-05
Identities = 54/268 (20%), Positives = 113/268 (42%), Gaps = 16/268 (5%)
Query: 126 IIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITK--------NE 177
+ + ++I LT ++L E + + S+ K+NI +K ++ +TK +
Sbjct: 75 VTEGTGDIIKALTERLDALLLEKAETEQQCLSLKKENIKMKQEVEDSVTKMGDAHKELEQ 134
Query: 178 TDIN---ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
+ IN E+ N L +V+S+Y+ L +QL A++ Q + E++ N+ +
Sbjct: 135 SHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELSEQLKFQNNSEDNVKK 194
Query: 235 XXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLI 294
K + + K V + + I+ +++++ I+ L E+L+
Sbjct: 195 LQEEIEKIRPGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELL 254
Query: 295 CDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF 354
+ E ++E L+ + + E E+ + E +L++Q +E N K E
Sbjct: 255 QLKAIHQEEVKE---LMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECEL 311
Query: 355 NKVSQIASDFKISNQLSCELDDESENTY 382
+ + S+ NQ+ L ENT+
Sbjct: 312 ENLRKATSNANQDNQICSIL--LQENTF 337
Score = 38.3 bits (85), Expect = 0.065
Identities = 48/195 (24%), Positives = 89/195 (45%), Gaps = 20/195 (10%)
Query: 268 VEEKLSEIKEKD--ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
+E+++ E++ K E I L E+L E ET Q+ LS L K+ K ++E+
Sbjct: 63 LEKEIEELRSKPVTEGTGDIIKALTERLDALLLEKAETEQQ---CLS-LKKENIKMKQEV 118
Query: 326 EEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERI 385
E+ ++ ++L + N K IEN+ N++ + S + + +E+ NT +
Sbjct: 119 EDSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLEL 178
Query: 386 SLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI-ADLTEQNIILKERLSQLETENK 444
S L K N+ DN + L E ++I EQ + L+++L E K
Sbjct: 179 SEQL-KFQNN------------SEDNVKKLQEEIEKIRPGFEEQILYLQKQLDATTDEKK 225
Query: 445 ELLIEIQTVRGSNEE 459
E + ++Q + +N +
Sbjct: 226 ETVTQLQNIIEANSQ 240
Score = 34.3 bits (75), Expect = 1.1
Identities = 71/364 (19%), Positives = 161/364 (44%), Gaps = 41/364 (11%)
Query: 107 ALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIK 166
+LK+ENI+M E+ DS+T+ + + E++ + K+ ++K
Sbjct: 106 SLKKENIKMK-------QEVEDSVTK-----------MGDAHKELEQSHINYVKEIENLK 147
Query: 167 TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLK 226
L + +K D L+ ++ E++ ++ + + F+ NN+ D +QEE++ ++
Sbjct: 148 NELMAVRSKYSEDKANLQKQLE--EAMNTQLELSEQLKFQ--NNSEDNVKKLQEEIEKIR 203
Query: 227 --IENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML--VEEKLSEIKEKDENF 282
E Q L ++ AN + + + ++E+L ++K +
Sbjct: 204 PGFEEQILYLQKQLDATTDEKKETVTQLQNIIEANSQHYQKNINSLQEELLQLKAIHQ-- 261
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQE-QLTHLMEQL-N 340
+E+ L ++ +E + + N L +L K+ +E+ +++K E +L +L + N
Sbjct: 262 -EEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLRKATSN 320
Query: 341 DTENN---SYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLT-LDKITNHI 396
++N S L EN F V Q+ ++ K+ + + ES+++ + +T ++ + +
Sbjct: 321 ANQDNQICSILLQENTF--VEQVVNE-KVKHLEDTLKELESQHSILKDEVTYMNNLKLKL 377
Query: 397 TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
I + ++ L ++ + + EQ ++++ S+L NK+ TV
Sbjct: 378 EMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQF---CYTVEQH 434
Query: 457 NEEV 460
N EV
Sbjct: 435 NREV 438
Score = 32.3 bits (70), Expect = 4.2
Identities = 41/207 (19%), Positives = 80/207 (38%), Gaps = 7/207 (3%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDL 153
LK ++++ EL + + H +++ + E+ ++L + + E LE
Sbjct: 256 LKAIHQEEVKELMCQIEASAKEHEAEINKLNELKENLVKQCEASEKNIQKKYECELENLR 315
Query: 154 KKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ---LNN 210
K S + I ++L + T E +NE +K+LE E + + L ++ +NN
Sbjct: 316 KATSNANQDNQICSILLQENTFVEQVVNE---KVKHLEDTLKELESQHSILKDEVTYMNN 372
Query: 211 AVDKQNCIQEEV-DLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
K + + D E ++L +A L + VE
Sbjct: 373 LKLKLEMDAQHIKDEFFHEREDLEFKINELLLAKEEQGCVIEKLKSELAGLNKQFCYTVE 432
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICD 296
+ E++ E ++EI LNE + D
Sbjct: 433 QHNREVQSLKEQHQKEISELNETFLSD 459
>AB191263-1|BAD52439.1| 1960|Homo sapiens non-muscle myosin heavy
polypeptide 9 protein.
Length = 1960
Score = 50.0 bits (114), Expect = 2e-05
Identities = 69/354 (19%), Positives = 144/354 (40%), Gaps = 23/354 (6%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLL--- 233
+ + +++ +I+ LE E +A +KL + K ++EE +L+ +N L
Sbjct: 935 QAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEK 994
Query: 234 QXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL 293
+ + K +A L+ ++ + L E ++E +QE++ KL
Sbjct: 995 KLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITD-LEERLRREEKQRQELEKTRRKL 1053
Query: 294 ICDRREFNETMQEKNILLSDLSKKVNKTEREL-------EEKQEQLTHLMEQLNDTENNS 346
D + ++ + E +++L ++ K E EL EE+ Q ++++ + E+
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 347 YKLIENM------FNKVSQIASDF-KISNQLSCELDDESENTYERISLTLDKITNHITYL 399
+L E++ NK + D + L EL+D ++T + L K + L
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELR-SKREQEVNIL 1172
Query: 400 NTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
+ E K AQ + E +++ + E+ L E+L Q + L QT+ E
Sbjct: 1173 KKTLEEEAKTHEAQ-IQEMRQKHSQAVEE---LAEQLEQTKRVKANLEKAKQTLENERGE 1228
Query: 460 VTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
+ +K ++++++ K E + +L D + + Q EL
Sbjct: 1229 LANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Score = 49.2 bits (112), Expect = 3e-05
Identities = 78/391 (19%), Positives = 160/391 (40%), Gaps = 35/391 (8%)
Query: 157 SITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQN 216
++T++ K+L KL K+E I +L ++ E + E KL + D+
Sbjct: 1007 NLTEEEEKSKSLA-KLKNKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIA 1065
Query: 217 CIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIK 276
+Q ++ LK++ + K I LE + L E+ SE
Sbjct: 1066 ELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERA 1125
Query: 277 EKDENFKQEIDMLNEKLICDRREFNETM--------------QEKNILLSDLSKKVNKTE 322
+++ KQ+ D L E+L + E +T+ QE NIL L ++ E
Sbjct: 1126 SRNKAEKQKRD-LGEELEALKTELEDTLDSTAAQQELRSKREQEVNILKKTLEEEAKTHE 1184
Query: 323 RELEEKQ-------EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+++E + E+L +EQ + N K + + N+ ++A++ K+ Q + +
Sbjct: 1185 AQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVKVLLQGKGDSE 1244
Query: 376 DES---ENTYERISLTLDKITNHITYLNTQINETQ-KNDNAQ-LLWEAKKQIADLTEQNI 430
+ E + + + ++ T L ++ + Q + DN LL ++ + + LT+
Sbjct: 1245 HKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFS 1304
Query: 431 ILKERLSQ----LETENKE---LLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
L+ +L L+ EN++ L +++ V L++
Sbjct: 1305 ALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEAKHNLEKQIATLHA 1364
Query: 484 EIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
++ DMK K+ + E ++V ++ QK+L+
Sbjct: 1365 QVADMKKKMEDSVGCLETAEEVKRKLQKDLE 1395
Score = 47.6 bits (108), Expect = 1e-04
Identities = 93/504 (18%), Positives = 200/504 (39%), Gaps = 35/504 (6%)
Query: 25 RLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKL 84
++ E +I +L+ L+ +K AE + ++ + L E
Sbjct: 1105 KIRELESQISELQEDLESERASRNK--AEKQKRDLGEELEALKTELEDTLDSTAAQQELR 1162
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
+ E + N LKK E+ A EA +E Q H+ V + E ++ V L ++L
Sbjct: 1163 SKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTL 1222
Query: 145 E----EVALEIDL---KKNSITKDNISIKTLLDKLITK-NETD---------INELRNSI 187
E E+A E+ + K ++ L +L K NE + + +L+ +
Sbjct: 1223 ENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVEL 1282
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXX---XXXXXXX 244
+ + S+ ++ + KL + +A++ Q +Q+ +LL+ EN+ L
Sbjct: 1283 DNVTGLLSQSDSKSSKLTKDF-SALESQ--LQDTQELLQEENRQKLSLSTKLKQVEDEKN 1339
Query: 245 XXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDEN---FKQEIDMLNEKLICDRREFN 301
++ NLE+ L +++++K+K E+ + + + KL D +
Sbjct: 1340 SFREQLEEEEEAKHNLEKQIATL-HAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLS 1398
Query: 302 ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
+ +EK L K + ++EL++ L H + + E K + + + I+
Sbjct: 1399 QRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQ-KKFDQLLAEEKTIS 1457
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKITN---HITYLNTQINETQKNDNAQLLWEA 418
+ + + E E ++ L++ + LN Q T+ D +
Sbjct: 1458 AKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQF-RTEMEDLMSSKDDV 1516
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXX 478
K + +L + L++++ +++T+ +EL E+Q + + +NL+
Sbjct: 1517 GKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGR 1576
Query: 479 XXXSNE-IEDMKTKVMEWKSQFED 501
S E + + +V E +++ ED
Sbjct: 1577 DEQSEEKKKQLVRQVREMEAELED 1600
Score = 46.4 bits (105), Expect = 2e-04
Identities = 55/255 (21%), Positives = 110/255 (43%), Gaps = 24/255 (9%)
Query: 269 EEKLSEIKEKDENFKQ---EIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
EE L++ KE ++ K E+ L E+L R + QE++ L +++ K L
Sbjct: 1662 EEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALAL 1721
Query: 326 EEK---QEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
EEK + ++ L E+L + + N+ +LI + K + + D +I+ L+ E +N
Sbjct: 1722 EEKRRLEARIAQLEEELEEEQGNT-ELINDRLKK-ANLQID-QINTDLNLERSHAQKN-- 1776
Query: 383 ERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETE 442
E L++ + ++ T K+ + + +IA L E QL+ E
Sbjct: 1777 ENARQQLERQNKELKVKLQEMEGTVKSKYKASITALEAKIAQLEE----------QLDNE 1826
Query: 443 NKELLIEIQTVRGSN---EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQF 499
KE + VR + ++V L + D S ++ +K ++ E + +
Sbjct: 1827 TKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEA 1886
Query: 500 EDLDDVMKQQQKELK 514
+ + ++ Q+EL+
Sbjct: 1887 QRANASRRKLQRELE 1901
Score = 45.6 bits (103), Expect = 4e-04
Identities = 79/465 (16%), Positives = 183/465 (39%), Gaps = 41/465 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L E L N +K D ELEALK E ++ E+ + +N L
Sbjct: 1116 LQEDLESERASRNKAEKQKRDLGEELEALKTE-LEDTLDSTAAQQELRSKREQEVNILKK 1174
Query: 140 GFES---LEEVALEIDLKKNSITKDNIS--------IKTLLDKLITKNETDINELRNSIK 188
E E ++ +K+S + ++ +K L+K E + EL N +K
Sbjct: 1175 TLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELANEVK 1234
Query: 189 YLESVKSEYNTANEKLFEQLNNAVDKQNC-------IQEEVDLLKIENQNLLQXXXXXXX 241
L K + +K+ QL K N + ++V L++E N+
Sbjct: 1235 VLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLSQSDS 1294
Query: 242 XXXXXXXXXXARDKFIANLEEM------KTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC 295
A + + + +E+ + + + KL +++++ +F+++++ E
Sbjct: 1295 KSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEEA--- 1351
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFN 355
+ + + + ++D+ KK+ + LE +E L + L + + ++
Sbjct: 1352 -KHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVA-AYD 1409
Query: 356 KVSQIASDFKIS-NQLSCELDDESENT--YERISLTLDKITNHITYLNTQINETQKNDNA 412
K+ + + + + L +LD + ++ E+ D++ ++ + E + A
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEA 1469
Query: 413 QLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXX 472
+ + K ++ L E+ ++LE NK+ E++ + S ++V ++ +
Sbjct: 1470 EAREKETKALS-LARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 473 XXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
++E+MKT++ E + + + +D + + L+ K
Sbjct: 1529 AL-------EQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMK 1566
Score = 44.0 bits (99), Expect = 0.001
Identities = 41/215 (19%), Positives = 94/215 (43%), Gaps = 7/215 (3%)
Query: 253 RDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
RD+ A E +T + L+ E+ K E++ LN++ + + + + +
Sbjct: 1464 RDRAEAEAREKETKALS--LARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVH 1521
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSC 372
+L K E+++EE + QL L ++L TE+ +L N+ +Q D + ++ S
Sbjct: 1522 ELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFERDLQGRDEQS- 1580
Query: 373 ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL 432
+++ + ++ ++ + + + +K + EA A+ I
Sbjct: 1581 --EEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEAHIDSANKNRDEAI- 1637
Query: 433 KERLSQLETENKELLIEIQTVRGSNEEVTLNLKDS 467
++L +L+ + K+ + E+ R S EE+ K++
Sbjct: 1638 -KQLRKLQAQMKDCMRELDDTRASREEILAQAKEN 1671
Score = 43.2 bits (97), Expect = 0.002
Identities = 54/257 (21%), Positives = 115/257 (44%), Gaps = 20/257 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+ K ++L E E++E+ +Q++ + EK+ + + + ++E+ I+L D + K+ K
Sbjct: 937 EKKKMQQNIQELEEQLEEEESARQKLQL--EKVTTEAKL--KKLEEEQIILEDQNCKLAK 992
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESEN 380
++ LE++ + T L + E S K + + NK + +D + +L E E
Sbjct: 993 EKKLLEDRIAEFT---TNLTEEEEKS-KSLAKLKNKHEAMITD--LEERLRRE-----EK 1041
Query: 381 TYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
+ + T K+ T L+ QI E Q AQ+ E K Q+A E+ R+ +
Sbjct: 1042 QRQELEKTRRKLEGDSTDLSDQIAELQ----AQIA-ELKMQLAKKEEELQAALARVEEEA 1096
Query: 441 TENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
+ L +I+ + E+ +L+ E+E +KT++ +
Sbjct: 1097 AQKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTA 1156
Query: 501 DLDDVMKQQQKELKLGK 517
++ ++++E+ + K
Sbjct: 1157 AQQELRSKREQEVNILK 1173
Score = 39.9 bits (89), Expect = 0.021
Identities = 49/282 (17%), Positives = 122/282 (43%), Gaps = 32/282 (11%)
Query: 261 EEMKTMLVEEKLSEIKEKD---ENFKQEIDMLNEKLICDRREFNETMQEKNILLSD---- 313
+E + M EE+L +++EK EN E++ L +L+ ++ + E +Q + L ++
Sbjct: 843 QEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQLQEQLQAETELCAEAEEL 902
Query: 314 ----------LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----- 358
L + + E +EE++E+ HL + + N +L E + + S
Sbjct: 903 RARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKL 962
Query: 359 ---QIASDFKIS--NQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQ-----K 408
++ ++ K+ + L+D++ + L D+I T L + +++ K
Sbjct: 963 QLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLK 1022
Query: 409 NDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSS 468
N + ++ + ++++ +Q L++ +LE ++ +L +I ++ E+ + L
Sbjct: 1023 NKHEAMITDLEERLRREEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKE 1082
Query: 469 TXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQ 510
+ + K+ E +SQ +L + ++ ++
Sbjct: 1083 EELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESER 1124
Score = 32.3 bits (70), Expect = 4.2
Identities = 33/134 (24%), Positives = 63/134 (47%), Gaps = 8/134 (5%)
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
+V++ E E+ K+E+L + E+ EN +L E + +A ++ QL E +
Sbjct: 839 QVSRQEEEMMAKEEELVKVREKQLAAEN---RLTEMETLQSQLMAEKLQLQEQLQAETEL 895
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI-ILKER 435
+E R LT K + + ++ + Q L KK++ +QNI L+E+
Sbjct: 896 CAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKM----QQNIQELEEQ 951
Query: 436 LSQLETENKELLIE 449
L + E+ ++L +E
Sbjct: 952 LEEEESARQKLQLE 965
>AB035898-1|BAB03309.1| 1388|Homo sapiens kinesin-like protein 2
protein.
Length = 1388
Score = 50.0 bits (114), Expect = 2e-05
Identities = 69/360 (19%), Positives = 154/360 (42%), Gaps = 30/360 (8%)
Query: 169 LDKLITKNE---TDINELR----NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEE 221
L + TKN+ +++++LR ++ K L SVK EY++ ++ N ++ +Q +
Sbjct: 786 LQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQ 845
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE---KLSEIKEK 278
+D L++EN+ LL+ +D + NL+E+ +++ L K++
Sbjct: 846 LDNLRLENEKLLE-------------SKACLQDSY-DNLQEIMKFEIDQLSRNLQNFKKE 891
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT-ERELEEKQEQLTHLME 337
+E K +++ L E L ++ N+ + + SK++ K E +EKQ++ +
Sbjct: 892 NETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQ 951
Query: 338 QLNDTENNSYKLI--ENMFNKVSQIA-SDFKISNQLSCELDDESENTYERISLTLDKITN 394
Q+ + L+ E + + + + SD K+ L ++ + + E+ T+D +
Sbjct: 952 QMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTE-TIDTLKQ 1010
Query: 395 HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVR 454
+ +N + N D + KKQ D+ + L+ R+ + E L ++
Sbjct: 1011 ELKDINCKYNSALV-DREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHAT 1069
Query: 455 GSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+T K S I++++ K+ + K + E + + ++L+
Sbjct: 1070 EQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLE 1129
Score = 41.9 bits (94), Expect = 0.005
Identities = 70/331 (21%), Positives = 139/331 (41%), Gaps = 24/331 (7%)
Query: 191 ESVKSEYNT-ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXX 249
E V E N A E + E+L ++ + +Q ++D + +N L Q
Sbjct: 701 EPVPPEMNEQAFEAISEELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQEL 760
Query: 250 XXA-RDKFIANLEEMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQE 306
+ R + EE+ + L +E++L E + K++ K E+ L L +E + E
Sbjct: 761 FSSERIDWTKQQEELLSQLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLE 820
Query: 307 KNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI 366
+ S K N+ E+E + E+ H+ QL++ + KL+E +K S +
Sbjct: 821 YS------SFKTNQ-EKEFNKLSERHMHVQLQLDNLRLENEKLLE---SKACLQDSYDNL 870
Query: 367 SNQLSCELDDESEN--TYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD 424
+ E+D S N +++ + TL N++ L E ++N+ L +E K+ +
Sbjct: 871 QEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEA--EKERNNKLSLQFEEDKENSS 928
Query: 425 LTEQNIILKERL-SQLETEN-KELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXS 482
++ R Q ET ++ + ++Q + S +
Sbjct: 929 KEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLM 988
Query: 483 NEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
N+I++++T V E + E + D +KQ+ K++
Sbjct: 989 NQIQELRTSVCE---KTETI-DTLKQELKDI 1015
Score = 35.9 bits (79), Expect = 0.34
Identities = 79/434 (18%), Positives = 169/434 (38%), Gaps = 29/434 (6%)
Query: 25 RLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKL 84
+LEE ++ S L+++ K VA+L N I++L L ++L
Sbjct: 958 KLEESLLATEKVISSLEKSRDSDKKVVADLMNQ-----IQELRTSVCEKTETIDTLKQEL 1012
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQM-HTSDVMVVPEIIDSLTEVINTLTNGFES 143
K+N E+S ++ + + + + T + ++ E I+ + L + E
Sbjct: 1013 KDINCKYNSALVDREESRVLIKKQEVDILDLKETLRLRILSEDIER-DMLCEDLAHATEQ 1071
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
L + E K + + + T + LI + + +N+ + + E K+EYN +
Sbjct: 1072 LNMLT-EASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEV---EQKKNEYNFKMRQ 1127
Query: 204 LFEQLNNAVDKQNCIQEE-------VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
L +++A + + LL+ + Q + R+
Sbjct: 1128 LEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVK 1187
Query: 257 IANLEEMKTMLVE-EKL----SEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
A + MK L E E L ++ EK+ + ++D + + + + Q KN
Sbjct: 1188 NAEILRMKEQLREMENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQE 1247
Query: 312 SDLSKKVNKTE--RELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
+ +++ K++ E+ + + L + L + E ++ + + + + F+ Q
Sbjct: 1248 ESIKERLAKSKIVEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQ 1307
Query: 370 LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQN 429
L +L++ E ER S ++ + + L E K Q L + + + L ++N
Sbjct: 1308 LRSKLEEMYEER-ERTSQEMEMLRKQVECL---AEENGKLVGHQNLHQKIQYVVRLKKEN 1363
Query: 430 IILKERLSQLETEN 443
+ L E +L EN
Sbjct: 1364 VRLAEETEKLRAEN 1377
Score = 34.7 bits (76), Expect = 0.80
Identities = 63/347 (18%), Positives = 144/347 (41%), Gaps = 27/347 (7%)
Query: 12 NENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXX 71
N+ +++ +H ++ L KE+ +K L+ + KT E + ++++ +
Sbjct: 793 NDFLKSEVHDLRVVLHSADKELSSVK--LEYS---SFKTNQEKEFNKLSERHMHVQLQLD 847
Query: 72 XXXXXXXXLTEKLTIAETKHNDLKKLYE---DSASE-LEALKRENIQMHTSDVMVVPEII 127
L E + +++L+++ + D S L+ K+EN + SD+ + E++
Sbjct: 848 NLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLK-SDLNNLMELL 906
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTL-LDKLITKNETDINELRNS 186
++ E N L+ FE +E + + LK + +T ++ + K + L +
Sbjct: 907 EAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLAT 966
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
K + S++ ++ + + + +N + + + E+ + + Q L
Sbjct: 967 EKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDR 1026
Query: 247 XXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD---ENFKQEIDMLNEKLICDRREFN-- 301
K ++ ++K L LSE E+D E+ + LN ++
Sbjct: 1027 EESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLL 1086
Query: 302 ----ETMQEKNILLSDLSKKVNKTERELEEKQE-------QLTHLME 337
E + +K L+ +L K+N+ + E+E+K+ QL H+M+
Sbjct: 1087 QSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMD 1133
>AB027133-1|BAB71953.1| 1390|Homo sapiens male enhanced antigen-2
protein.
Length = 1390
Score = 50.0 bits (114), Expect = 2e-05
Identities = 50/289 (17%), Positives = 131/289 (45%), Gaps = 16/289 (5%)
Query: 95 KKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLK 154
K L E E+ AL + ++ V+ + + + + ES +++ALE++ +
Sbjct: 1058 KTLLEKELQEVIALTSQELEESREKVLELEDELQESRGFRKKIKRLEESNKKLALELEHE 1117
Query: 155 KNSIT---KDNISIK---TLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQL 208
K +T + N +++ ++L+ + K E D+ +L ++ + K E + + L + L
Sbjct: 1118 KGKLTGLGQSNAALREHNSILETALAKREADLVQLNLQVQAVLQRKEEEDRQMKHLVQAL 1177
Query: 209 NNAVDKQ----NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE-EM 263
+++K+ N ++E+V K+E + + A++ + L+ E
Sbjct: 1178 QASLEKEKEKVNSLKEQVAAAKVEAGHNRRHFKAASLELSEVKKELQAKEHLVQKLQAEA 1237
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK---NILLSDLSKKVNK 320
+ + E + ++ F+ E+ +L +++ +E + ++ N + +L +V++
Sbjct: 1238 DDLQIRE--GKHSQEIAQFQAELAEARAQLQLLQKQLDEQLSKQPVGNQEMENLKWEVDQ 1295
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
ERE++ ++QL +Q +L++N+ +++ D ++ +
Sbjct: 1296 KEREIQSLKQQLDLTEQQGRKELEGLQQLLQNVKSELEMAQEDLSMTQK 1344
Score = 42.7 bits (96), Expect = 0.003
Identities = 47/236 (19%), Positives = 101/236 (42%), Gaps = 11/236 (4%)
Query: 104 ELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNI 163
+LEAL++E++ + + + E + S + ++ L ++ L+ E+ + S +D I
Sbjct: 711 QLEALQQEHLDL-MKQLTLTQEALQSREQSLDALQTHYDELQARLGELQGEAAS-REDTI 768
Query: 164 SI----KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQ 219
+ K +L+ + ++ EL + LE E + EKL E+L + +Q
Sbjct: 769 CLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKSGQVEHLQ 828
Query: 220 EEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD 279
+E LK + Q + + ++D+ I+ L+ + L + +L E++++
Sbjct: 829 QETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRL-DSELKELRQEL 887
Query: 280 ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL 335
E +L RE + Q ++DL + ++E +E + L L
Sbjct: 888 MQVHGEKRTAEAELSRLHREVAQVRQH----MADLEGHLQSAQKERDEMETHLQSL 939
Score = 36.7 bits (81), Expect = 0.20
Identities = 49/233 (21%), Positives = 102/233 (43%), Gaps = 21/233 (9%)
Query: 258 ANLEEMKTMLVEEK--LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLS 315
A+ E+ +L EK L + ++ K+E+D +L E +ET+++ L+ S
Sbjct: 762 ASREDTICLLQNEKIILEAALQAAKSGKEELDRGARRLEEGTEETSETLEKLREELAIKS 821
Query: 316 KKVNKTERELEEKQEQLTHLMEQLNDTE----------NNSYKLIENMFNKVSQIASDFK 365
+V ++E ++Q+ + EQ + + +LI + ++ S+ K
Sbjct: 822 GQVEHLQQETAALKKQMQKIKEQFLQQKVMVEAYRRDATSKDQLISELKATRKRLDSELK 881
Query: 366 ISNQLSCELDDE---SENTYERISLTLDKITNHITYLNTQINETQKN-----DNAQLLWE 417
Q ++ E +E R+ + ++ H+ L + QK + Q L
Sbjct: 882 ELRQELMQVHGEKRTAEAELSRLHREVAQVRQHMADLEGHLQSAQKERDEMETHLQSLQF 941
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIE-IQTVRGSNEEVTLNLKDSST 469
K+Q+ +TE N LK+++ +L+ E ++ + E Q +R ++T K+ T
Sbjct: 942 DKEQMVAVTEANEALKKQIEELQQEARKAITEQKQKMRRLGSDLTSAQKEMKT 994
>M36769-1|AAC17185.1| 1937|Homo sapiens perinatal myosin heavy chain
protein.
Length = 1937
Score = 49.6 bits (113), Expect = 3e-05
Identities = 84/444 (18%), Positives = 178/444 (40%), Gaps = 31/444 (6%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L EK+ + NDL+ + A L + Q+ + + L I +T
Sbjct: 876 LEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQ--------LEAKIKEVTE 927
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKL---ITKNETDINELRNSIKYLESVKSE 196
E EE+ E+ KK + + +K +D L + K E + N +K L +
Sbjct: 928 RAEEEEEINAELTAKKRKLEDECSELKKDIDDLELTLAKVEKQKHATENKVKNLTEEMAG 987
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ--NLLQXXXXXXXXXXXXXXXXXARD 254
+ KL ++ A+ + + Q+ +D L+ E N+L ++
Sbjct: 988 LDETIAKLSKE-KKALQETH--QQTLDDLQAEEDKVNILTKAKTKLEQQVDDLEGSLEQE 1044
Query: 255 KFIA-NLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
K + +LE K L + KL++ D EN KQ++D EK + ++++ +
Sbjct: 1045 KKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEISNLISKIEDEQAVE 1104
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLS 371
L KK+ + + +EE E++ E L + ++S+ + +
Sbjct: 1105 IQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSREL-EEISERLEEAGGATSAQ 1163
Query: 372 CELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
EL+ + E ++++ L++ T + + + + A+L +QI +L
Sbjct: 1164 VELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAEL----GEQIDNLQRVKQK 1219
Query: 432 LKERLSQLETENKELLIEIQTV---RGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEI--- 485
L++ S+L+ E +L + + +G E++ +L+D + N++
Sbjct: 1220 LEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSLEDQVSGLKTKEEEQQRLINDLTAQ 1279
Query: 486 -EDMKTKVMEWKSQFEDLDDVMKQ 508
++T+ E+ Q ++ D ++ Q
Sbjct: 1280 RARLQTEAGEYSRQLDEQDALVSQ 1303
Score = 48.4 bits (110), Expect = 6e-05
Identities = 89/483 (18%), Positives = 190/483 (39%), Gaps = 40/483 (8%)
Query: 43 NVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLK--KLYED 100
N+ KT E + D++ + Q L L +A+ D++ K D
Sbjct: 1021 NILTKAKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLD 1080
Query: 101 SASELEALKRENIQMHTSDVMVVP----EIIDSLTEVINTLTNGFESLEEVALEIDLKKN 156
E + + N+ D V + I L I L E+ + + +++
Sbjct: 1081 EKLEKKEFEISNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRS 1140
Query: 157 SITKDNISIKTLLDKL--ITKNETDINELRNS-IKYLESVKSEYNTANEKLFEQLNNA-V 212
++++ I L++ T + ++N+ R + + L E +E + L
Sbjct: 1141 DLSRELEEISERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHA 1200
Query: 213 DKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKL 272
D + E++D L+ Q L + A K +LE+M L E+++
Sbjct: 1201 DSMAELGEQIDNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGHLEKMCRSL-EDQV 1259
Query: 273 SEIKEKDENFKQEIDMLNE---KLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
S +K K+E ++ I+ L +L + E++ + E++ L+S LS+ + +++EE
Sbjct: 1260 SGLKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEQDALVSQLSRSKQASTQQIEE-- 1317
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
L H +E+ +N +++ + + + ++E E E + L
Sbjct: 1318 --LKHQLEEETKAKNALAHALQSSRHDCDLLREQY----------EEEQEGKAE-LQRAL 1364
Query: 390 DKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIE 449
K + + T+ ET + L EAKK++A ++ +E + + + L
Sbjct: 1365 SKANSEVAQWRTKY-ETDAIQRTEELEEAKKKLAQRLQE---AEEHVEAVNAKCASLEKT 1420
Query: 450 IQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQ 509
Q ++ E++ L+++ S+ + + + EWK ++E+ ++
Sbjct: 1421 KQRLQNEVEDLMLDVERSNAACAAL-------DKKQRNFDKVLSEWKQKYEETQAELEAS 1473
Query: 510 QKE 512
QKE
Sbjct: 1474 QKE 1476
Score = 46.0 bits (104), Expect = 3e-04
Identities = 90/465 (19%), Positives = 196/465 (42%), Gaps = 34/465 (7%)
Query: 26 LEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLTEK 83
LEE K++ Q +++V + A L+ + + + + L L +K
Sbjct: 1389 LEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKK 1448
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
+ ++ K+ YE++ +ELEA ++E+ + T ++ V + + + + TL ++
Sbjct: 1449 QRNFDKVLSEWKQKYEETQAELEASQKESRSLST-ELFKVKNVYEESLDQLETLRRAHKN 1507
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLE-SVKSEYNTANE 202
L++ EI I + I L+K+ + E + E++ +++ E S++ E
Sbjct: 1508 LQQ---EISDLTEQIAEGGKQIHE-LEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILR 1563
Query: 203 KLFE--QLNNAVDKQNCIQ-EEVDLLKIENQNLLQX-XXXXXXXXXXXXXXXXARDKFIA 258
E Q+ + VD++ + EE+D LK + +++ + K
Sbjct: 1564 IQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEG 1623
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL--ICDRREFNETMQEK--------N 308
+L EM+ L E N++ +L E + D E ++E+ N
Sbjct: 1624 DLNEMEIQL-NHANRLAAESLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRAN 1682
Query: 309 IL---LSDLSKKVNKTERELEEKQEQLTHLME--QLNDTENNS-YKLIENMFNKVSQIAS 362
+L + +L + +TER + +++L E QL T+N S + + N VSQ+ S
Sbjct: 1683 LLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQS 1742
Query: 363 DFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
+ + Q S +++++ ++ +++ +T + + N + + +
Sbjct: 1743 EVEEVIQESRNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNLEQTVKDLQHR 1799
Query: 423 ADLTEQNIIL--KERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
D EQ + K+++ +LE +EL E++ + N E L+
Sbjct: 1800 LDEAEQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLR 1844
Score = 41.1 bits (92), Expect = 0.009
Identities = 52/262 (19%), Positives = 115/262 (43%), Gaps = 28/262 (10%)
Query: 255 KFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL 314
K I LE++K + +EK EI+ E + ++ K++ + E N+ + S++
Sbjct: 1524 KQIHELEKIKKQVEQEKC-EIQAALEEAEASLEHEEGKILRIQLELNQ-------VKSEV 1575
Query: 315 SKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+K+ + + E+++ + T ++E + T + + + ++ D N++ +L
Sbjct: 1576 DRKIAEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDL---NEMEIQL 1632
Query: 375 DDESENTYERISLTLDKITNHITYLNTQ--INETQKNDNAQLLWEAKKQIADLTEQNIIL 432
+ + L + + N Y NTQ + ETQ + L +A + DL EQ I+
Sbjct: 1633 NHANR-------LAAESLRN---YRNTQGILKETQLH-----LDDALRGQEDLKEQLAIV 1677
Query: 433 KERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKV 492
+ R + L+ E +EL ++ S + L D+S N + ++ V
Sbjct: 1678 ERRANLLQAEIEELWATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDV 1737
Query: 493 MEWKSQFEDLDDVMKQQQKELK 514
+ +S+ E++ + +++ K
Sbjct: 1738 SQLQSEVEEVIQESRNAEEKAK 1759
Score = 37.5 bits (83), Expect = 0.11
Identities = 37/221 (16%), Positives = 99/221 (44%), Gaps = 6/221 (2%)
Query: 302 ETMQEKNILLSDLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
ET +E + + K ++ K+E + +E +E++ L+++ ND + +++ +
Sbjct: 847 ETEKEMATMKEEFQKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEE 906
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKN-DNAQLLWE 417
+ K QL ++ + +E E + + +T L + +E +K+ D+ +L
Sbjct: 907 RCEQLIKNKIQLEAKIKEVTERAEEEEEINAE-LTAKKRKLEDECSELKKDIDDLELTLA 965
Query: 418 AKKQIADLTEQNI-ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXX 476
++ TE + L E ++ L+ +L E + ++ ++++ +L+
Sbjct: 966 KVEKQKHATENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNILTK 1025
Query: 477 XXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKLGK 517
+++D++ + + K DL+ ++ + +LKL +
Sbjct: 1026 AKTKLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQ 1066
Score = 32.7 bits (71), Expect = 3.2
Identities = 50/264 (18%), Positives = 107/264 (40%), Gaps = 15/264 (5%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTN 139
L E+L I E + N L+ E+ + LE +R ++ +++ E + L +L N
Sbjct: 1670 LKEQLAIVERRANLLQAEIEELWATLEQTERSR-KIAEQELLDASERVQLLHTQNTSLIN 1728
Query: 140 GFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELR---NSIKYLESVKSE 196
+ LE ++ + + +++ + + K IT EL+ ++ +LE +K
Sbjct: 1729 TKKKLENDVSQLQSEVEEVIQESRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKN 1788
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
+ L +L+ A +Q ++ ++ + + K
Sbjct: 1789 LEQTVKDLQHRLDEA--EQLALKGGKKQIQKLEARVRELEGEVENEQKRNAEAVKGLRKH 1846
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
++E+ E++ + ++ +D +D L K+ +R+ E ++ N LS
Sbjct: 1847 DRRVKELTYQTEEDRKNVLRLQDL-----VDKLQAKVKSYKRQAEEAEEQSNANLS---- 1897
Query: 317 KVNKTERELEEKQEQLTHLMEQLN 340
K K + ELEE +E+ Q+N
Sbjct: 1898 KFRKLQHELEEAEERADIAESQVN 1921
>BC064391-1|AAH64391.1| 474|Homo sapiens coiled-coil domain
containing 6 protein.
Length = 474
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/262 (21%), Positives = 111/262 (42%), Gaps = 16/262 (6%)
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L +L + + ++ E++ K++ + L + ++FI+N
Sbjct: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTL 116
Query: 262 EMKTMLVE---EKLSEIKEKDENF-KQEIDMLNEKLICDRREFNETM-QEKNILLSDLSK 316
K ++ E L+ EK+E F E+ +L ++ E + + QE+ ++ L K
Sbjct: 117 FKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMK 176
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
K+ K E + KQ L L + D EN + E + N++ + + ++ E D
Sbjct: 177 KIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLD 236
Query: 377 E---SENTYERISLTLDKITN---HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI 430
+ + + IS+ +D N HI +L ++ +K A L ++K L E+
Sbjct: 237 QPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERH 296
Query: 431 ILKERLS-----QLETENKELL 447
+ +E L Q E E +E L
Sbjct: 297 MREENLRLQRKLQREMERREAL 318
>BC036757-1|AAH36757.2| 474|Homo sapiens coiled-coil domain
containing 6 protein.
Length = 474
Score = 49.6 bits (113), Expect = 3e-05
Identities = 57/262 (21%), Positives = 111/262 (42%), Gaps = 16/262 (6%)
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L +L + + ++ E++ K++ + L + ++FI+N
Sbjct: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTL 116
Query: 262 EMKTMLVE---EKLSEIKEKDENF-KQEIDMLNEKLICDRREFNETM-QEKNILLSDLSK 316
K ++ E L+ EK+E F E+ +L ++ E + + QE+ ++ L K
Sbjct: 117 FKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMK 176
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
K+ K E + KQ L L + D EN + E + N++ + + ++ E D
Sbjct: 177 KIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLD 236
Query: 377 E---SENTYERISLTLDKITN---HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI 430
+ + + IS+ +D N HI +L ++ +K A L ++K L E+
Sbjct: 237 QPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERH 296
Query: 431 ILKERLS-----QLETENKELL 447
+ +E L Q E E +E L
Sbjct: 297 MREENLRLQRKLQREMERREAL 318
>AK000990-1|BAA91457.1| 535|Homo sapiens protein ( Homo sapiens
cDNA FLJ10128 fis, clone HEMBA1002997, weakly similar to
CENTROMERIC PROTEIN E. ).
Length = 535
Score = 49.6 bits (113), Expect = 3e-05
Identities = 79/386 (20%), Positives = 149/386 (38%), Gaps = 24/386 (6%)
Query: 7 TLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQL 66
T+F E I A K + E K++ +LK + G + + L ++ N
Sbjct: 149 TVFVPPEKHEKEIIALKSNIVELKKQLSELK----KKCGEDQEKIHALTSENTNLKKMMS 204
Query: 67 XXXXXXXXXXXXXLTEKLTIAETKHN--DLKKLYEDSASELEALKRENI----QMHTSDV 120
+T T+A+T D+KK +ED E +K +N + +
Sbjct: 205 NQYVPVKTHEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQN 264
Query: 121 MVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKL-ITKNETD 179
+ E I SL E +++ +S+ +V + K I TL ++ K E D
Sbjct: 265 QIKAEYI-SLAEHEAKMSSLSQSMRKVQDSNAEILANYRKGQEEIVTLHAEIKAQKKELD 323
Query: 180 INELRNSIKY-----LESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
+ +KY E + ++ ++L +QL+ K + +EEV K EN L +
Sbjct: 324 TIQECIKVKYAPIVSFEECERKFKATEKELKDQLSEQTQKYSVSEEEVKKNKQENDKLKK 383
Query: 235 XXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEK---DENFKQEIDMLNE 291
+ L KT + ++L ++ +K +N K+++ N
Sbjct: 384 EIFTLQKDLRDKTVLIEKSHEMERALSR-KTDELNKQLKDLSQKYTEVKNVKEKLVEENA 442
Query: 292 KLICDRREFNETMQEKNILLSD---LSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
K + +Q++++ L L K +N T L+E+ + + E+ T ++
Sbjct: 443 KQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQRCYEKEQQTVTKLHQ 502
Query: 349 LIENMFNKVSQIASDFKISNQLSCEL 374
L+EN N +A +I E+
Sbjct: 503 LLENQKNSSVPLAEHLQIKEAFEKEV 528
Score = 46.4 bits (105), Expect = 2e-04
Identities = 95/455 (20%), Positives = 190/455 (41%), Gaps = 42/455 (9%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEI 151
+++ +E S SE+ LKRE N++ + V PE + +V + L L + E+
Sbjct: 1 MEREHEKSLSEIRQLKRELENVKAKLAQ-HVKPEEHE---QVKSRLEQKSGELGKKITEL 56
Query: 152 DLKKNSITKDNISIKTLLDKLITKNETDIN-ELRNS---IKYLESVKSEYNTANEKLFEQ 207
LK ++ K+ I L +KL+ + ++ E++N +K E +K ++ + L +
Sbjct: 57 TLKNQTLQKE-IEKVYLDNKLLKEQAHNLTIEMKNHYVPLKVSEDMKKSHDAIIDDLNRK 115
Query: 208 LNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML 267
L + K + E++ L +EN +L + +N+ E+K L
Sbjct: 116 LLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFVPPEKHEKEIIALKSNIVELKKQL 175
Query: 268 VE--EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTEREL 325
E +K E +EK E L +K++ ++ +T +E + L+D K N+ ++
Sbjct: 176 SELKKKCGEDQEKIHALTSENTNL-KKMMSNQYVPVKTHEEVKMTLNDTLAKTNRELLDV 234
Query: 326 EEKQEQLTHLMEQLNDTENNSYKLIENMFNKVS----QIASDFKISNQLSCELDDESENT 381
++K E + ++ D + +EN N++ +A + LS + ++
Sbjct: 235 KKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYISLAEHEAKMSSLSQSMRKVQDSN 294
Query: 382 YERISLTLDKITNHITYLNTQINETQKN-DNAQLLWEAK------------------KQI 422
E I K I L+ +I +K D Q + K K++
Sbjct: 295 AE-ILANYRKGQEEIVTLHAEIKAQKKELDTIQECIKVKYAPIVSFEECERKFKATEKEL 353
Query: 423 AD-LTEQN---IILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXX 478
D L+EQ + +E + + + EN +L EI T++ + T+ ++ S
Sbjct: 354 KDQLSEQTQKYSVSEEEVKKNKQENDKLKKEIFTLQKDLRDKTVLIEKSHEMERALSRKT 413
Query: 479 XXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
+ +++D+ K E K+ E L + +Q E+
Sbjct: 414 DELNKQLKDLSQKYTEVKNVKEKLVEENAKQTSEI 448
Score = 35.1 bits (77), Expect = 0.60
Identities = 93/501 (18%), Positives = 197/501 (39%), Gaps = 46/501 (9%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAEL--KNDEINSMIRQLXXXXXXXXXXXXXLTEKLT--- 85
+E Q+KS L+Q G K + EL KN + I ++ LT ++
Sbjct: 33 EEHEQVKSRLEQKSGELGKKITELTLKNQTLQKEIEKVYLDNKLLKEQAHNLTIEMKNHY 92
Query: 86 IAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEII---DSLTEVINTLTNGFE 142
+ D+KK ++ +L + Q +T + + +++ DSL++ ++ L F
Sbjct: 93 VPLKVSEDMKKSHDAIIDDLNRKLLDVTQKYTEKKLEMEKLLLENDSLSKDVSRLETVFV 152
Query: 143 SLEEVALEIDLKKNSITKDNISIKTLLDKL---------ITKNETDINELRNS----IKY 189
E+ EI K++I + + L K +T T++ ++ ++ +K
Sbjct: 153 PPEKHEKEIIALKSNIVELKKQLSELKKKCGEDQEKIHALTSENTNLKKMMSNQYVPVKT 212
Query: 190 LESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXX 249
E VK N K +L + K I +E +K +N+ L +
Sbjct: 213 HEEVKMTLNDTLAKTNRELLDVKKKFEDINQEFVKIKDKNEILKRNLENTQNQIKAEYIS 272
Query: 250 XXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNI 309
+ +++L + V++ +EI ++EI L+ ++ ++E +T+QE
Sbjct: 273 LAEHEAKMSSLSQSMRK-VQDSNAEILANYRKGQEEIVTLHAEIKAQKKEL-DTIQECIK 330
Query: 310 LLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
+ + ER+ + +++L +QL++ + Y + E K Q
Sbjct: 331 VKYAPIVSFEECERKFKATEKELK---DQLSE-QTQKYSVSEEEVKKNKQ---------- 376
Query: 370 LSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQN 429
E++ + I TL K T L + +E ++ + + E KQ+ DL+++
Sbjct: 377 -------ENDKLKKEI-FTLQKDLRDKTVLIEKSHEMERALSRKTD-ELNKQLKDLSQKY 427
Query: 430 IILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
+K +L EN + EI V+ ++ + L+ E++ M+
Sbjct: 428 TEVKNVKEKLVEENAKQTSEILAVQNLLQKQHVPLEQVEALKKSLNGTIENLKEELKSMQ 487
Query: 490 TKVMEWKSQFEDLDDVMKQQQ 510
+ + L +++ Q+
Sbjct: 488 RCYEKEQQTVTKLHQLLENQK 508
>X78998-1|CAA55632.1| 1411|Homo sapiens endosomal protein protein.
Length = 1411
Score = 49.2 bits (112), Expect = 3e-05
Identities = 77/408 (18%), Positives = 172/408 (42%), Gaps = 26/408 (6%)
Query: 53 ELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKREN 112
+++++E+N+ I+ L +L+ + K + + ++S SE E ++
Sbjct: 824 KIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQKG 883
Query: 113 IQMHTSDVMVVPEIIDSL-TEVINTLTNGFE---SLE---EVALEIDLKKNSITKDNISI 165
E+ L ++ NTL E SLE E + ++ L+ NS+ + I
Sbjct: 884 KAAILDLEKTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASHQLKLELNSMQEQLIQA 943
Query: 166 KTLL---DKLITKNETDINELRNSI----KYLESVKSEYNTA-------NEKLFEQLNNA 211
+ L +K + + +INEL+ S K +E+++ E A KL +QL A
Sbjct: 944 QNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQGELKIAVLQKTELENKLQQQLTQA 1003
Query: 212 VDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEK 271
+ +E++ +L+ + + A + + ++EE ++ E+
Sbjct: 1004 AQELAAEKEKISVLQNNYEKSQETFKQLQSDFYGRESELLATRQDLKSVEEKLSLAQEDL 1063
Query: 272 LSEIKEKDENFK--QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
+S + K QE+ L D + + +QE+ L D+ K+ + E+EL ++
Sbjct: 1064 ISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQQLQERCKALQDIQKEKSLKEKELVNEK 1123
Query: 330 EQLTHLMEQLNDTENNSYKLIENM-FNKVSQI--ASDFKISNQLSCELDDESENTYERIS 386
+L + E E KL E + +K+ I ++ K + QL + E + + +
Sbjct: 1124 SKLAEIEEIKCRQEKEITKLNEELKSHKLESIKEITNLKDAKQLLIQQKLELQGKADSLK 1183
Query: 387 LTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
+++ + L Q+ + ++ + + + K +++ E+ + +K+
Sbjct: 1184 AAVEQEKRNQQILKDQVKKEEEELKKEFIEKEAKLHSEIKEKEVGMKK 1231
Score = 48.4 bits (110), Expect = 6e-05
Identities = 74/415 (17%), Positives = 171/415 (41%), Gaps = 36/415 (8%)
Query: 101 SASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITK 160
SA + +R ++Q H + + +N +T L++V ++ K+ ++
Sbjct: 653 SAEAAKTAQRADLQNHLDTAQ---NALQDKQQELNKITT---QLDQVTAKLQDKQEHCSQ 706
Query: 161 DNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQE 220
+K +K ++ E EL IK LE+ E + E+ + L +Q +
Sbjct: 707 LESHLKEYKEKYLSL-EQKTEELEGQIKKLEADSLEVKASKEQALQDLQ----QQRQLNT 761
Query: 221 EVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDE 280
+++L E L+ K LE +K +KL++ +E+ +
Sbjct: 762 DLELRATELSKQLEMEKEIVSSTRLDL------QKKSEALESIK-----QKLTKQEEEKQ 810
Query: 281 NFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLN 340
KQ+ + L+++ E N +Q L + + EL +++L+ + + L
Sbjct: 811 ILKQDFETLSQETKIQHEELNNRIQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLK 870
Query: 341 DTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENT---YERISLTLDKITNHIT 397
++++ K EN K + + + K +L +L + ENT + + +L+K
Sbjct: 871 NSKSEFEK--ENQKGKAAILDLE-KTCKELKHQLQVQMENTLKEQKELKKSLEKEKEASH 927
Query: 398 YLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSN 457
L ++N Q+ QL+ +A+ + ++ L+ +++L+ +++ +I+ ++G
Sbjct: 928 QLKLELNSMQE----QLI-QAQNTLKQNEKEEQQLQGNINELKQSSEQKKKQIEALQG-- 980
Query: 458 EEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKE 512
E+ + + + + E+ K K+ ++ +E + KQ Q +
Sbjct: 981 -ELKIAVLQKTELENKLQQQLTQAAQELAAEKEKISVLQNNYEKSQETFKQLQSD 1034
Score = 46.8 bits (106), Expect = 2e-04
Identities = 91/498 (18%), Positives = 215/498 (43%), Gaps = 55/498 (11%)
Query: 27 EECYKE---IGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEK 83
EE KE I LK+ L Q G+ D V + + ++ +++ + +K
Sbjct: 198 EELNKEATVIQDLKTELLQRPGIEDVAVLKKELVQVQTLMDNMTLERERESEKLKDECKK 257
Query: 84 LTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES 143
L ++++ + SEL A + + ++ ++ + ++ LT+ TLT
Sbjct: 258 L---QSQYASSEATISQLRSEL-AKGPQEVAVYVQELQKLKSSVNELTQKNQTLTENLLK 313
Query: 144 LEEVALEIDLKKN--SITKDNISIKTLLDKLIT--KNETDINELRNSIKYLESVKSEYNT 199
E+ +++ K N S++K NI TL K + + ++ ++ S+ + SE
Sbjct: 314 KEQDYTKLEEKHNEESVSKKNIQA-TLHQKDLDCQQLQSRLSASETSLHRIHVELSEKGE 372
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
A +KL E+L+ ++ + LK E + L Q R++
Sbjct: 373 ATQKLKEELSE-------VETKYQHLKAEFKQLQQQ-----------------REE---- 404
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
+E + ++ +++++ K ++++ + +L R+ +E + +K ++DL K++
Sbjct: 405 -KEQHGLQLQSEINQLHSKLLETERQLGEAHGRLKEQRQLSSEKLMDKEQQVADLQLKLS 463
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYK---LIENMFNKVSQIASDFKISNQLSCELDD 376
+ E +L+EK T L QL+ T+ + L ++ K+ + +D + Q+ ++ D
Sbjct: 464 RLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTAKLREAQNDLE---QVLRQIGD 520
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD-LTEQNIILKER 435
+ + + + L K +I+ L + + A E + + + L E+N L+E+
Sbjct: 521 KDQK-IQNLEALLQKSKENISLLEKEREDLYAKIQA---GEGETAVLNQLQEKNHTLQEQ 576
Query: 436 LSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEW 495
++QL ++L + ++ + + E + +++ + ++ +++ E
Sbjct: 577 VTQL---TEKLKNQSESHKQAQENLHDQVQEQKAHLRAAQDRVLSLETSVNELNSQLNES 633
Query: 496 KSQFEDLDDVMKQQQKEL 513
K + LD +K + + L
Sbjct: 634 KEKVSQLDIQIKAKTELL 651
>S72869-1|AAC60637.1| 585|Homo sapiens H4(D10S170) protein.
Length = 585
Score = 49.2 bits (112), Expect = 3e-05
Identities = 57/262 (21%), Positives = 111/262 (42%), Gaps = 16/262 (6%)
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L +L + + ++ E++ K++ + L + ++FI+N
Sbjct: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTL 116
Query: 262 EMKTMLVE---EKLSEIKEKDENF-KQEIDMLNEKLICDRREFNETM-QEKNILLSDLSK 316
K ++ E L+ EK+E F E+ +L ++ E + + QE+ ++ L K
Sbjct: 117 FKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKGELEQHLEQEQEFQVNKLMK 176
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
K+ K E + KQ L L + D EN + E + N++ + + ++ E D
Sbjct: 177 KIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAETRILQEKLD 236
Query: 377 E---SENTYERISLTLDKITN---HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI 430
+ + + IS+ +D N HI +L ++ +K A L ++K L E+
Sbjct: 237 QPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERH 296
Query: 431 ILKERLS-----QLETENKELL 447
+ +E L Q E E +E L
Sbjct: 297 MREENLRLQRKLQREMERREAL 318
>BC130564-1|AAI30565.1| 905|Homo sapiens KIAA1524 protein.
Length = 905
Score = 49.2 bits (112), Expect = 3e-05
Identities = 42/200 (21%), Positives = 92/200 (46%), Gaps = 10/200 (5%)
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMF---NKVSQIASDFKISNQLSCELDDESE 379
RE+E K E+L+ L++ + IE++F K+ +A + +I + EL +E
Sbjct: 680 REVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNE 739
Query: 380 NTYER---ISLTLDKITNHI---TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
+T ++ + +T D + I LN + E + AQL+ E ++Q ++ Q + +
Sbjct: 740 STEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLI-EKEEQRKEVQNQLVDRE 798
Query: 434 ERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
+L+ L + K +I+T++ E+ + S + ++ +
Sbjct: 799 HKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKA 858
Query: 494 EWKSQFEDLDDVMKQQQKEL 513
+ + + E+ + ++K QQ+EL
Sbjct: 859 QLEGRLEEKESLVKLQQEEL 878
Score = 41.9 bits (94), Expect = 0.005
Identities = 45/181 (24%), Positives = 85/181 (46%), Gaps = 22/181 (12%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFE--QLNNAVDKQN------C--IQEEVDLLK 226
++DI L + LESV E+ + E Q N + +K+N C + ++++ +K
Sbjct: 704 QSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVK 763
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXA-------RDKFIANLEEMKTMLVEEKLSEIKEKD 279
N++L + R+ +ANL + KT + EEK+ ++++
Sbjct: 764 KLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQ-KTKVQEEKIKTLQKER 822
Query: 280 ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQL 339
E+ ++ ID+L ++L R E + +E +I S L + + E LEEK+ + E+L
Sbjct: 823 EDKEETIDILRKEL--SRTE--QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
Query: 340 N 340
N
Sbjct: 879 N 879
Score = 35.5 bits (78), Expect = 0.46
Identities = 46/260 (17%), Positives = 101/260 (38%), Gaps = 15/260 (5%)
Query: 146 EVALEIDLKKNSITKDNISIKTLL----DKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E+ L K S +D + K L D+LI ++ + + L S+ E N
Sbjct: 627 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 686
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L L + Q +++ L N+ L + +
Sbjct: 687 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 746
Query: 262 EMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
+++ + +++ +K+ +E+ K++ NEK I E E +E L D K+
Sbjct: 747 DLQITCDSLNKQIETVKKLNESLKEQ----NEKSIAQLIEKEEQRKEVQNQLVDREHKLA 802
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQL---SCELD 375
++ + ++E++ L ++ D E + ++ ++ QI + I ++ L +L+
Sbjct: 803 NLHQKTKVQEEKIKTLQKEREDKE-ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLE 861
Query: 376 DESENTYERISLTLDKITNH 395
E + L +++ H
Sbjct: 862 GRLEEKESLVKLQQEELNKH 881
>BC126266-1|AAI26267.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 49.2 bits (112), Expect = 3e-05
Identities = 83/396 (20%), Positives = 160/396 (40%), Gaps = 47/396 (11%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+S E+ L +E ++ LE + KK K+ + LL + IT+ E N++++
Sbjct: 234 NSRLEMHFKLKEDYEKIQH--LEQEYKKEINDKEK-QVSLLLIQ-ITEKE---NKMKDLT 286
Query: 188 KYLESVKSEYNTANEKL---FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
LE + + N EK E L +++KQ+ + +E++ +K+ Q +
Sbjct: 287 FLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQ 346
Query: 245 XXXXXXXARDKFIANL-EEMKTMLVEEKLSEIKEKD--ENFKQEIDMLNEKLICDRREFN 301
K I L EE +T + E + F+ + L E L +++
Sbjct: 347 IAT-------KTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLE 399
Query: 302 ETMQEKNILLSDLSKKVNKTERELE---EKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
+ + IL +L KK ++ E + K+ +L L + L + E Y+ F K
Sbjct: 400 KNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYE--NKQFEK-- 455
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEA 418
IA + K + Q L E + + L IT Y + ++ +
Sbjct: 456 -IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL------------ 502
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXX 478
K ++ + +N L ++L ENKEL E ++TL LK+
Sbjct: 503 KTELENEKLKNTELTSHCNKLSLENKELTQE-------TSDMTLELKNQQEDINNNKKQE 555
Query: 479 XXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+IE+++ + +++ E + + +KQ++ E+K
Sbjct: 556 ERMLKQIENLQETETQLRNELEYVREELKQKRDEVK 591
Score = 44.4 bits (100), Expect = 0.001
Identities = 79/416 (18%), Positives = 165/416 (39%), Gaps = 37/416 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELE----ALKRENIQMHTSDVMVVPEIIDSLTEVINTL 137
EK E + + +++Y D + +E A + +Q S + + ++ + ++ +
Sbjct: 195 EKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLE 254
Query: 138 TNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL-----ES 192
+ + + ++ L IT+ +K L L+ ++ +N+L K +S
Sbjct: 255 QEYKKEINDKEKQVSLLLIQITEKENKMKDLTF-LLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 193 VKSEYNTANE--KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXX 250
++ +++ E + L +V Q ++E+ L+I + + Q
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVSTQKALEED---LQIATKTICQLTEEKETQMEESNKAR 370
Query: 251 XARDKFIANLEEMKTMLVEEKLSEIK--EKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
A + E L E +E + EK+E+ + + M +K + E + K
Sbjct: 371 AAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKE 430
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF---- 364
+ L +L K + + E L E + Q + E+L TE L++ +V +
Sbjct: 431 VELEELKKVLGEKETLLYENK-QFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAIT 489
Query: 365 -------KISNQLSCELDDES-ENTY-----ERISLTLDKITNHITYLNTQINETQKNDN 411
K L EL++E +NT ++SL ++T + + ++ Q++ N
Sbjct: 490 TSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN 549
Query: 412 AQLLWEAK--KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
E + KQI +L E L+ L + E K+ E++ +EE NL+
Sbjct: 550 NNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Score = 33.9 bits (74), Expect = 1.4
Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 8/162 (4%)
Query: 298 REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV 357
+E N T N+L ++ KT++ E++E M D NN K+I F ++
Sbjct: 174 KENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM----DLNNNIEKMI-TAFEEL 228
Query: 358 SQIASDFKISNQLSCELDDES-ENTYERISLTLDKITNHITYLNTQINETQK--NDNAQL 414
A + ++ + D E ++ + ++ ++ L QI E + D L
Sbjct: 229 RVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL 288
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
L E++ ++ L E+ + E L Q + L E++ ++ S
Sbjct: 289 LEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVS 330
>BC022284-1|AAH22284.1| 334|Homo sapiens Unknown (protein for
IMAGE:4762273) protein.
Length = 334
Score = 49.2 bits (112), Expect = 3e-05
Identities = 52/245 (21%), Positives = 105/245 (42%), Gaps = 11/245 (4%)
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L +L + + ++ E++ K++ + L + ++FI+N
Sbjct: 57 EELTNRLASLQQENKVLKIELETYKLKCKALQEENRDLRKASVTIQARAEQEEEFISNTL 116
Query: 262 EMKTMLVE---EKLSEIKEKDENF-KQEIDMLNEKLICDRREFNETM-QEKNILLSDLSK 316
K ++ E L+ EK+E F E+ +L ++ E + + QE+ ++ L K
Sbjct: 117 FKKIQALQKEKETLAVNYEKEEEFLTNELSRKLMQLQHEKAELEQHLEQEQEFQVNKLMK 176
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
K+ K E + KQ L L + D EN + E + N++ + + ++ E D
Sbjct: 177 KIKKLENDTISKQLTLEQLRREKIDLENTLEQEQEALVNRLWKRMDKLEAEKRILQEKLD 236
Query: 377 E---SENTYERISLTLDKITN---HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNI 430
+ + + IS+ +D N HI +L ++ +K A L ++K L E+
Sbjct: 237 QPVSAPPSPRDISMEIDSPENMMRHIRFLKNEVERLKKQLRAAQLQHSEKMAQYLEEERH 296
Query: 431 ILKER 435
+ +ER
Sbjct: 297 MREER 301
>BC017659-1|AAH17659.1| 285|Homo sapiens KIAA1524 protein protein.
Length = 285
Score = 49.2 bits (112), Expect = 3e-05
Identities = 42/200 (21%), Positives = 92/200 (46%), Gaps = 10/200 (5%)
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMF---NKVSQIASDFKISNQLSCELDDESE 379
RE+E K E+L+ L++ + IE++F K+ +A + +I + EL +E
Sbjct: 60 REVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNE 119
Query: 380 NTYER---ISLTLDKITNHI---TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
+T ++ + +T D + I LN + E + AQL+ E ++Q ++ Q + +
Sbjct: 120 STEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLI-EKEEQRKEVQNQLVDRE 178
Query: 434 ERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
+L+ L + K +I+T++ E+ + S + ++ +
Sbjct: 179 HKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKA 238
Query: 494 EWKSQFEDLDDVMKQQQKEL 513
+ + + E+ + ++K QQ+EL
Sbjct: 239 QLEGRLEEKESLVKLQQEEL 258
Score = 41.9 bits (94), Expect = 0.005
Identities = 45/181 (24%), Positives = 85/181 (46%), Gaps = 22/181 (12%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFE--QLNNAVDKQN------C--IQEEVDLLK 226
++DI L + LESV E+ + E Q N + +K+N C + ++++ +K
Sbjct: 84 QSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVK 143
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXA-------RDKFIANLEEMKTMLVEEKLSEIKEKD 279
N++L + R+ +ANL + KT + EEK+ ++++
Sbjct: 144 KLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQ-KTKVQEEKIKTLQKER 202
Query: 280 ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQL 339
E+ ++ ID+L ++L R E + +E +I S L + + E LEEK+ + E+L
Sbjct: 203 EDKEETIDILRKEL--SRTE--QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 258
Query: 340 N 340
N
Sbjct: 259 N 259
Score = 35.5 bits (78), Expect = 0.46
Identities = 46/260 (17%), Positives = 101/260 (38%), Gaps = 15/260 (5%)
Query: 146 EVALEIDLKKNSITKDNISIKTLL----DKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E+ L K S +D + K L D+LI ++ + + L S+ E N
Sbjct: 7 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 66
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L L + Q +++ L N+ L + +
Sbjct: 67 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 126
Query: 262 EMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
+++ + +++ +K+ +E+ K++ NEK I E E +E L D K+
Sbjct: 127 DLQITCDSLNKQIETVKKLNESLKEQ----NEKSIAQLIEKEEQRKEVQNQLVDREHKLA 182
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQL---SCELD 375
++ + ++E++ L ++ D E + ++ ++ QI + I ++ L +L+
Sbjct: 183 NLHQKTKVQEEKIKTLQKEREDKE-ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLE 241
Query: 376 DESENTYERISLTLDKITNH 395
E + L +++ H
Sbjct: 242 GRLEEKESLVKLQQEELNKH 261
>AL645502-1|CAH70064.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 49.2 bits (112), Expect = 3e-05
Identities = 83/396 (20%), Positives = 160/396 (40%), Gaps = 47/396 (11%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+S E+ L +E ++ LE + KK K+ + LL + IT+ E N++++
Sbjct: 234 NSRLEMHFKLKEDYEKIQH--LEQEYKKEINDKEK-QVSLLLIQ-ITEKE---NKMKDLT 286
Query: 188 KYLESVKSEYNTANEKL---FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
LE + + N EK E L +++KQ+ + +E++ +K+ Q +
Sbjct: 287 FLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQ 346
Query: 245 XXXXXXXARDKFIANL-EEMKTMLVEEKLSEIKEKD--ENFKQEIDMLNEKLICDRREFN 301
K I L EE +T + E + F+ + L E L +++
Sbjct: 347 IAT-------KTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLE 399
Query: 302 ETMQEKNILLSDLSKKVNKTERELE---EKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
+ + IL +L KK ++ E + K+ +L L + L + E Y+ F K
Sbjct: 400 KNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYE--NKQFEK-- 455
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEA 418
IA + K + Q L E + + L IT Y + ++ +
Sbjct: 456 -IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL------------ 502
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXX 478
K ++ + +N L ++L ENKEL E ++TL LK+
Sbjct: 503 KTELENEKLKNTELTSHCNKLSLENKELTQE-------TSDMTLELKNQQEDINNNKKQE 555
Query: 479 XXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+IE+++ + +++ E + + +KQ++ E+K
Sbjct: 556 ERMLKQIENLQETETQLRNELEYVREELKQKRDEVK 591
Score = 44.4 bits (100), Expect = 0.001
Identities = 79/416 (18%), Positives = 165/416 (39%), Gaps = 37/416 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELE----ALKRENIQMHTSDVMVVPEIIDSLTEVINTL 137
EK E + + +++Y D + +E A + +Q S + + ++ + ++ +
Sbjct: 195 EKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLE 254
Query: 138 TNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL-----ES 192
+ + + ++ L IT+ +K L L+ ++ +N+L K +S
Sbjct: 255 QEYKKEINDKEKQVSLLLIQITEKENKMKDLTF-LLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 193 VKSEYNTANE--KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXX 250
++ +++ E + L +V Q ++E+ L+I + + Q
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVSTQKALEED---LQIATKTICQLTEEKETQMEESNKAR 370
Query: 251 XARDKFIANLEEMKTMLVEEKLSEIK--EKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
A + E L E +E + EK+E+ + + M +K + E + K
Sbjct: 371 AAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKE 430
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF---- 364
+ L +L K + + E L E + Q + E+L TE L++ +V +
Sbjct: 431 VELEELKKVLGEKETLLYENK-QFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAIT 489
Query: 365 -------KISNQLSCELDDES-ENTY-----ERISLTLDKITNHITYLNTQINETQKNDN 411
K L EL++E +NT ++SL ++T + + ++ Q++ N
Sbjct: 490 TSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN 549
Query: 412 AQLLWEAK--KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
E + KQI +L E L+ L + E K+ E++ +EE NL+
Sbjct: 550 NNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Score = 33.9 bits (74), Expect = 1.4
Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 8/162 (4%)
Query: 298 REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV 357
+E N T N+L ++ KT++ E++E M D NN K+I F ++
Sbjct: 174 KENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM----DLNNNIEKMI-TAFEEL 228
Query: 358 SQIASDFKISNQLSCELDDES-ENTYERISLTLDKITNHITYLNTQINETQK--NDNAQL 414
A + ++ + D E ++ + ++ ++ L QI E + D L
Sbjct: 229 RVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL 288
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
L E++ ++ L E+ + E L Q + L E++ ++ S
Sbjct: 289 LEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVS 330
>AL358372-3|CAH72848.1| 792|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 792
Score = 49.2 bits (112), Expect = 3e-05
Identities = 83/396 (20%), Positives = 160/396 (40%), Gaps = 47/396 (11%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+S E+ L +E ++ LE + KK K+ + LL + IT+ E N++++
Sbjct: 234 NSRLEMHFKLKEDYEKIQH--LEQEYKKEINDKEK-QVSLLLIQ-ITEKE---NKMKDLT 286
Query: 188 KYLESVKSEYNTANEKL---FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
LE + + N EK E L +++KQ+ + +E++ +K+ Q +
Sbjct: 287 FLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQ 346
Query: 245 XXXXXXXARDKFIANL-EEMKTMLVEEKLSEIKEKD--ENFKQEIDMLNEKLICDRREFN 301
K I L EE +T + E + F+ + L E L +++
Sbjct: 347 IAT-------KTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLE 399
Query: 302 ETMQEKNILLSDLSKKVNKTERELE---EKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
+ + IL +L KK ++ E + K+ +L L + L + E Y+ F K
Sbjct: 400 KNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYE--NKQFEK-- 455
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEA 418
IA + K + Q L E + + L IT Y + ++ +
Sbjct: 456 -IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL------------ 502
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXX 478
K ++ + +N L ++L ENKEL E ++TL LK+
Sbjct: 503 KTELENEKLKNTELTSHCNKLSLENKELTQE-------TSDMTLELKNQQEDINNNKKQE 555
Query: 479 XXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+IE+++ + +++ E + + +KQ++ E+K
Sbjct: 556 ERMLKQIENLQETETQLRNELEYVREELKQKRDEVK 591
Score = 44.4 bits (100), Expect = 0.001
Identities = 79/416 (18%), Positives = 165/416 (39%), Gaps = 37/416 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELE----ALKRENIQMHTSDVMVVPEIIDSLTEVINTL 137
EK E + + +++Y D + +E A + +Q S + + ++ + ++ +
Sbjct: 195 EKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLE 254
Query: 138 TNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL-----ES 192
+ + + ++ L IT+ +K L L+ ++ +N+L K +S
Sbjct: 255 QEYKKEINDKEKQVSLLLIQITEKENKMKDLTF-LLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 193 VKSEYNTANE--KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXX 250
++ +++ E + L +V Q ++E+ L+I + + Q
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVSTQKALEED---LQIATKTICQLTEEKETQMEESNKAR 370
Query: 251 XARDKFIANLEEMKTMLVEEKLSEIK--EKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
A + E L E +E + EK+E+ + + M +K + E + K
Sbjct: 371 AAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKE 430
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF---- 364
+ L +L K + + E L E + Q + E+L TE L++ +V +
Sbjct: 431 VELEELKKVLGEKETLLYENK-QFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAIT 489
Query: 365 -------KISNQLSCELDDES-ENTY-----ERISLTLDKITNHITYLNTQINETQKNDN 411
K L EL++E +NT ++SL ++T + + ++ Q++ N
Sbjct: 490 TSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN 549
Query: 412 AQLLWEAK--KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
E + KQI +L E L+ L + E K+ E++ +EE NL+
Sbjct: 550 NNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Score = 33.9 bits (74), Expect = 1.4
Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 8/162 (4%)
Query: 298 REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV 357
+E N T N+L ++ KT++ E++E M D NN K+I F ++
Sbjct: 174 KENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM----DLNNNIEKMI-TAFEEL 228
Query: 358 SQIASDFKISNQLSCELDDES-ENTYERISLTLDKITNHITYLNTQINETQK--NDNAQL 414
A + ++ + D E ++ + ++ ++ L QI E + D L
Sbjct: 229 RVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL 288
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
L E++ ++ L E+ + E L Q + L E++ ++ S
Sbjct: 289 LEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVS 330
>AL358372-2|CAH72847.1| 976|Homo sapiens synaptonemal complex
protein 1 protein.
Length = 976
Score = 49.2 bits (112), Expect = 3e-05
Identities = 83/396 (20%), Positives = 160/396 (40%), Gaps = 47/396 (11%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+S E+ L +E ++ LE + KK K+ + LL + IT+ E N++++
Sbjct: 234 NSRLEMHFKLKEDYEKIQH--LEQEYKKEINDKEK-QVSLLLIQ-ITEKE---NKMKDLT 286
Query: 188 KYLESVKSEYNTANEKL---FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
LE + + N EK E L +++KQ+ + +E++ +K+ Q +
Sbjct: 287 FLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQ 346
Query: 245 XXXXXXXARDKFIANL-EEMKTMLVEEKLSEIKEKD--ENFKQEIDMLNEKLICDRREFN 301
K I L EE +T + E + F+ + L E L +++
Sbjct: 347 IAT-------KTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLE 399
Query: 302 ETMQEKNILLSDLSKKVNKTERELE---EKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
+ + IL +L KK ++ E + K+ +L L + L + E Y+ F K
Sbjct: 400 KNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYE--NKQFEK-- 455
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEA 418
IA + K + Q L E + + L IT Y + ++ +
Sbjct: 456 -IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL------------ 502
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXX 478
K ++ + +N L ++L ENKEL E ++TL LK+
Sbjct: 503 KTELENEKLKNTELTSHCNKLSLENKELTQE-------TSDMTLELKNQQEDINNNKKQE 555
Query: 479 XXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+IE+++ + +++ E + + +KQ++ E+K
Sbjct: 556 ERMLKQIENLQETETQLRNELEYVREELKQKRDEVK 591
Score = 44.4 bits (100), Expect = 0.001
Identities = 79/416 (18%), Positives = 165/416 (39%), Gaps = 37/416 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELE----ALKRENIQMHTSDVMVVPEIIDSLTEVINTL 137
EK E + + +++Y D + +E A + +Q S + + ++ + ++ +
Sbjct: 195 EKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLE 254
Query: 138 TNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL-----ES 192
+ + + ++ L IT+ +K L L+ ++ +N+L K +S
Sbjct: 255 QEYKKEINDKEKQVSLLLIQITEKENKMKDLTF-LLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 193 VKSEYNTANE--KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXX 250
++ +++ E + L +V Q ++E+ L+I + + Q
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVSTQKALEED---LQIATKTICQLTEEKETQMEESNKAR 370
Query: 251 XARDKFIANLEEMKTMLVEEKLSEIK--EKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
A + E L E +E + EK+E+ + + M +K + E + K
Sbjct: 371 AAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKE 430
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF---- 364
+ L +L K + + E L E + Q + E+L TE L++ +V +
Sbjct: 431 VELEELKKVLGEKETLLYENK-QFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAIT 489
Query: 365 -------KISNQLSCELDDES-ENTY-----ERISLTLDKITNHITYLNTQINETQKNDN 411
K L EL++E +NT ++SL ++T + + ++ Q++ N
Sbjct: 490 TSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN 549
Query: 412 AQLLWEAK--KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
E + KQI +L E L+ L + E K+ E++ +EE NL+
Sbjct: 550 NNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Score = 33.9 bits (74), Expect = 1.4
Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 8/162 (4%)
Query: 298 REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV 357
+E N T N+L ++ KT++ E++E M D NN K+I F ++
Sbjct: 174 KENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM----DLNNNIEKMI-TAFEEL 228
Query: 358 SQIASDFKISNQLSCELDDES-ENTYERISLTLDKITNHITYLNTQINETQK--NDNAQL 414
A + ++ + D E ++ + ++ ++ L QI E + D L
Sbjct: 229 RVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL 288
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
L E++ ++ L E+ + E L Q + L E++ ++ S
Sbjct: 289 LEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVS 330
>AK022912-1|BAB14305.1| 472|Homo sapiens protein ( Homo sapiens
cDNA FLJ12850 fis, clone NT2RP2003394, weakly similar to
INTRACELLULAR PROTEIN TRANSPORT PROTEIN USO1. ).
Length = 472
Score = 49.2 bits (112), Expect = 3e-05
Identities = 42/200 (21%), Positives = 92/200 (46%), Gaps = 10/200 (5%)
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMF---NKVSQIASDFKISNQLSCELDDESE 379
RE+E K E+L+ L++ + IE++F K+ +A + +I + EL +E
Sbjct: 247 REVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNE 306
Query: 380 NTYER---ISLTLDKITNHI---TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
+T ++ + +T D + I LN + E + AQL+ E ++Q ++ Q + +
Sbjct: 307 STEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLI-EKEEQRKEVQNQLVDRE 365
Query: 434 ERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
+L+ L + K +I+T++ E+ + S + ++ +
Sbjct: 366 HKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKA 425
Query: 494 EWKSQFEDLDDVMKQQQKEL 513
+ + + E+ + ++K QQ+EL
Sbjct: 426 QLEGRLEEKESLVKLQQEEL 445
Score = 41.9 bits (94), Expect = 0.005
Identities = 45/181 (24%), Positives = 85/181 (46%), Gaps = 22/181 (12%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFE--QLNNAVDKQN------C--IQEEVDLLK 226
++DI L + LESV E+ + E Q N + +K+N C + ++++ +K
Sbjct: 271 QSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVK 330
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXA-------RDKFIANLEEMKTMLVEEKLSEIKEKD 279
N++L + R+ +ANL + KT + EEK+ ++++
Sbjct: 331 KLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQ-KTKVQEEKIKTLQKER 389
Query: 280 ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQL 339
E+ ++ ID+L ++L R E + +E +I S L + + E LEEK+ + E+L
Sbjct: 390 EDKEETIDILRKEL--SRTE--QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 445
Query: 340 N 340
N
Sbjct: 446 N 446
Score = 35.5 bits (78), Expect = 0.46
Identities = 46/260 (17%), Positives = 101/260 (38%), Gaps = 15/260 (5%)
Query: 146 EVALEIDLKKNSITKDNISIKTLL----DKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E+ L K S +D + K L D+LI ++ + + L S+ E N
Sbjct: 194 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 253
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L L + Q +++ L N+ L + +
Sbjct: 254 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 313
Query: 262 EMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
+++ + +++ +K+ +E+ K++ NEK I E E +E L D K+
Sbjct: 314 DLQITCDSLNKQIETVKKLNESLKEQ----NEKSIAQLIEKEEQRKEVQNQLVDREHKLA 369
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQL---SCELD 375
++ + ++E++ L ++ D E + ++ ++ QI + I ++ L +L+
Sbjct: 370 NLHQKTKVQEEKIKTLQKEREDKE-ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLE 428
Query: 376 DESENTYERISLTLDKITNH 395
E + L +++ H
Sbjct: 429 GRLEEKESLVKLQQEELNKH 448
>AF334474-1|AAL11632.1| 905|Homo sapiens p90 autoantigen protein.
Length = 905
Score = 49.2 bits (112), Expect = 3e-05
Identities = 42/200 (21%), Positives = 92/200 (46%), Gaps = 10/200 (5%)
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMF---NKVSQIASDFKISNQLSCELDDESE 379
RE+E K E+L+ L++ + IE++F K+ +A + +I + EL +E
Sbjct: 680 REVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNE 739
Query: 380 NTYER---ISLTLDKITNHI---TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
+T ++ + +T D + I LN + E + AQL+ E ++Q ++ Q + +
Sbjct: 740 STEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLI-EKEEQRKEVQNQLVDRE 798
Query: 434 ERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
+L+ L + K +I+T++ E+ + S + ++ +
Sbjct: 799 HKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKA 858
Query: 494 EWKSQFEDLDDVMKQQQKEL 513
+ + + E+ + ++K QQ+EL
Sbjct: 859 QLEGRLEEKESLVKLQQEEL 878
Score = 41.9 bits (94), Expect = 0.005
Identities = 45/181 (24%), Positives = 85/181 (46%), Gaps = 22/181 (12%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFE--QLNNAVDKQN------C--IQEEVDLLK 226
++DI L + LESV E+ + E Q N + +K+N C + ++++ +K
Sbjct: 704 QSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVK 763
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXA-------RDKFIANLEEMKTMLVEEKLSEIKEKD 279
N++L + R+ +ANL + KT + EEK+ ++++
Sbjct: 764 KLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQ-KTKVQEEKIKTLQKER 822
Query: 280 ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQL 339
E+ ++ ID+L ++L R E + +E +I S L + + E LEEK+ + E+L
Sbjct: 823 EDKEETIDILRKEL--SRTE--QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 878
Query: 340 N 340
N
Sbjct: 879 N 879
Score = 35.5 bits (78), Expect = 0.46
Identities = 46/260 (17%), Positives = 101/260 (38%), Gaps = 15/260 (5%)
Query: 146 EVALEIDLKKNSITKDNISIKTLL----DKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E+ L K S +D + K L D+LI ++ + + L S+ E N
Sbjct: 627 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 686
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L L + Q +++ L N+ L + +
Sbjct: 687 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 746
Query: 262 EMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
+++ + +++ +K+ +E+ K++ NEK I E E +E L D K+
Sbjct: 747 DLQITCDSLNKQIETVKKLNESLKEQ----NEKSIAQLIEKEEQRKEVQNQLVDREHKLA 802
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQL---SCELD 375
++ + ++E++ L ++ D E + ++ ++ QI + I ++ L +L+
Sbjct: 803 NLHQKTKVQEEKIKTLQKEREDKE-ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLE 861
Query: 376 DESENTYERISLTLDKITNH 395
E + L +++ H
Sbjct: 862 GRLEEKESLVKLQQEELNKH 881
>AF273043-1|AAG34903.1| 795|Homo sapiens CTCL tumor antigen se2-1
protein.
Length = 795
Score = 49.2 bits (112), Expect = 3e-05
Identities = 83/396 (20%), Positives = 160/396 (40%), Gaps = 47/396 (11%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+S E+ L +E ++ LE + KK K+ + LL + IT+ E N++++
Sbjct: 234 NSRLEMHFKLKEDYEKIQH--LEQEYKKEINDKEK-QVSLLLIQ-ITEKE---NKMKDLT 286
Query: 188 KYLESVKSEYNTANEKL---FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXX 244
LE + + N EK E L +++KQ+ + +E++ +K+ Q +
Sbjct: 287 FLLEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVSLQRSVSTQKALEEDLQ 346
Query: 245 XXXXXXXARDKFIANL-EEMKTMLVEEKLSEIKEKD--ENFKQEIDMLNEKLICDRREFN 301
K I L EE +T + E + F+ + L E L +++
Sbjct: 347 IAT-------KTICQLTEEKETQMEESNKARAAHSFVVTEFETTVCSLEELLRTEQQRLE 399
Query: 302 ETMQEKNILLSDLSKKVNKTERELE---EKQEQLTHLMEQLNDTENNSYKLIENMFNKVS 358
+ + IL +L KK ++ E + K+ +L L + L + E Y+ F K
Sbjct: 400 KNEDQLKILTMELQKKSSELEEMTKLTNNKEVELEELKKVLGEKETLLYE--NKQFEK-- 455
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEA 418
IA + K + Q L E + + L IT Y + ++ +
Sbjct: 456 -IAEELKGTEQELIGLLQAREKEVHDLEIQLTAITTSEQYYSKEVKDL------------ 502
Query: 419 KKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXX 478
K ++ + +N L ++L ENKEL E ++TL LK+
Sbjct: 503 KTELENEKLKNTELTSHCNKLSLENKELTQE-------TSDMTLELKNQQEDINNNKKQE 555
Query: 479 XXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+IE+++ + +++ E + + +KQ++ E+K
Sbjct: 556 ERMLKQIENLQETETQLRNELEYVREELKQKRDEVK 591
Score = 44.4 bits (100), Expect = 0.001
Identities = 79/416 (18%), Positives = 165/416 (39%), Gaps = 37/416 (8%)
Query: 82 EKLTIAETKHNDLKKLYEDSASELE----ALKRENIQMHTSDVMVVPEIIDSLTEVINTL 137
EK E + + +++Y D + +E A + +Q S + + ++ + ++ +
Sbjct: 195 EKTKKYEYEREETRQVYMDLNNNIEKMITAFEELRVQAENSRLEMHFKLKEDYEKIQHLE 254
Query: 138 TNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYL-----ES 192
+ + + ++ L IT+ +K L L+ ++ +N+L K +S
Sbjct: 255 QEYKKEINDKEKQVSLLLIQITEKENKMKDLTF-LLEESRDKVNQLEEKTKLQSENLKQS 313
Query: 193 VKSEYNTANE--KLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXX 250
++ +++ E + L +V Q ++E+ L+I + + Q
Sbjct: 314 IEKQHHLTKELEDIKVSLQRSVSTQKALEED---LQIATKTICQLTEEKETQMEESNKAR 370
Query: 251 XARDKFIANLEEMKTMLVEEKLSEIK--EKDENFKQEIDMLNEKLICDRREFNETMQEKN 308
A + E L E +E + EK+E+ + + M +K + E + K
Sbjct: 371 AAHSFVVTEFETTVCSLEELLRTEQQRLEKNEDQLKILTMELQKKSSELEEMTKLTNNKE 430
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF---- 364
+ L +L K + + E L E + Q + E+L TE L++ +V +
Sbjct: 431 VELEELKKVLGEKETLLYENK-QFEKIAEELKGTEQELIGLLQAREKEVHDLEIQLTAIT 489
Query: 365 -------KISNQLSCELDDES-ENTY-----ERISLTLDKITNHITYLNTQINETQKNDN 411
K L EL++E +NT ++SL ++T + + ++ Q++ N
Sbjct: 490 TSEQYYSKEVKDLKTELENEKLKNTELTSHCNKLSLENKELTQETSDMTLELKNQQEDIN 549
Query: 412 AQLLWEAK--KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
E + KQI +L E L+ L + E K+ E++ +EE NL+
Sbjct: 550 NNKKQEERMLKQIENLQETETQLRNELEYVREELKQKRDEVKCKLDKSEENCNNLR 605
Score = 33.9 bits (74), Expect = 1.4
Identities = 35/162 (21%), Positives = 69/162 (42%), Gaps = 8/162 (4%)
Query: 298 REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV 357
+E N T N+L ++ KT++ E++E M D NN K+I F ++
Sbjct: 174 KENNATRHLCNLLKETCARSAEKTKKYEYEREETRQVYM----DLNNNIEKMI-TAFEEL 228
Query: 358 SQIASDFKISNQLSCELDDES-ENTYERISLTLDKITNHITYLNTQINETQK--NDNAQL 414
A + ++ + D E ++ + ++ ++ L QI E + D L
Sbjct: 229 RVQAENSRLEMHFKLKEDYEKIQHLEQEYKKEINDKEKQVSLLLIQITEKENKMKDLTFL 288
Query: 415 LWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGS 456
L E++ ++ L E+ + E L Q + L E++ ++ S
Sbjct: 289 LEESRDKVNQLEEKTKLQSENLKQSIEKQHHLTKELEDIKVS 330
>AB209693-1|BAD92930.1| 1310|Homo sapiens golgi autoantigen, golgin
subfamily a, 4 variant protein.
Length = 1310
Score = 49.2 bits (112), Expect = 3e-05
Identities = 91/442 (20%), Positives = 190/442 (42%), Gaps = 31/442 (7%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEII--DSLTEVINTLTNGFESLEEVALE- 150
L+KL+E + E + +Q + ++ S +E + ++ E E +ALE
Sbjct: 512 LQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK-ISQEKEQQESLALEE 570
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN 210
++L+K +I ++ + L + T I EL +S LE E ++ L L
Sbjct: 571 LELQKKAILTESENKLRDLQQEAETYRTRILELESS---LEKSLQENKNQSKDLAVHLEA 627
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE 270
+K N +E+ ++ +++ L+ + ++ +E+++ +E
Sbjct: 628 EKNKHN---KEITVMVEKHKTELESLKHQQDALWTEKLQVL-KQQYQTEMEKLREKCEQE 683
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNET-MQEKNILLSDLSKKVNKTERELEEKQ 329
K + +K+K+ F+ I+ +NEK + ++ + +T ++ + LS++ K +K E EL +
Sbjct: 684 KETLLKDKEIIFQAHIEEMNEKTL-EKLDVKQTELESLSSELSEVLKARHKLEEELSVLK 742
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+Q T M+Q + + + K + +V I + ++S Q + + + N E +
Sbjct: 743 DQ-TDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKER 799
Query: 390 DKITN----HITYLNTQINETQ--------KNDNAQLLWEA-KKQIADLTEQNIILKERL 436
DK H+ L I ++ K D Q A +Q EQ L+++L
Sbjct: 800 DKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKL 859
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED-MKTKVMEW 495
LETE L ++ V ++V L ++E+E +K+ +
Sbjct: 860 LDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVY 919
Query: 496 KSQFEDLDDVMKQQQKELKLGK 517
+S+ ED + ++Q K++ + K
Sbjct: 920 ESKLED-GNKEQEQTKQILVEK 940
Score = 48.4 bits (110), Expect = 6e-05
Identities = 53/214 (24%), Positives = 100/214 (46%), Gaps = 15/214 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNK 320
E+ K +LVE++ + I + E K+EI++L +KL + +E + KK+ K
Sbjct: 931 EQTKQILVEKE-NMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFKNQEKKMEK 989
Query: 321 TERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF-----KISNQLSCELD 375
+++ +E QE L ++L D E K +EN ++SQ F +++ S +
Sbjct: 990 VKQKAKEMQET---LKKKLLDQEAKLKKELENTALELSQKEKQFNAKMLEMAQANSAGIS 1046
Query: 376 DESENTYERISLTLDKITN-HITYLNTQIN--ETQKNDNAQLLWEAKK-QIADLTEQNII 431
D ++ +T H LN I+ E + N A+ L E + Q+ + ++
Sbjct: 1047 DAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAE 1106
Query: 432 LKERLSQLETENKELLIEIQTVR--GSNEEVTLN 463
LK+++ E +E+ EI ++ G ++ TLN
Sbjct: 1107 LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLN 1140
Score = 34.3 bits (75), Expect = 1.1
Identities = 63/294 (21%), Positives = 117/294 (39%), Gaps = 26/294 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRE-NIQMHTSDVMVVPEIIDSLTEVINTLT 138
L +KL E K LKK E++A EL +++ N +M I D+++ +
Sbjct: 1001 LKKKLLDQEAK---LKKELENTALELSQKEKQFNAKMLEMAQANSAGISDAVSRLETNQK 1057
Query: 139 NGFESLEEVALE-----IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESV 193
ESL EV I + + + + ++ + + + + E ++ EL+ I
Sbjct: 1058 EQIESLTEVHRRELNDVISIWEKKLNQQAEELQEIHEIQLQEKEQEVAELKQKILLFGCE 1117
Query: 194 KSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXAR 253
K E N L K+ ++++ L +++ Q L Q
Sbjct: 1118 KEEMNKEITWL---------KEEGVKQDTTLNELQEQ-LKQKSAHVNSLAQDETKLKAHL 1167
Query: 254 DKFIANLEEM--KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREF---NETMQEKN 308
+K +L + + ++E+L E+K E K+++ L KL EF + ++ N
Sbjct: 1168 EKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKLKTTDEEFQSLKSSHEKSN 1227
Query: 309 ILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIAS 362
L D S + K EL + + E L + + N +LI +K + I S
Sbjct: 1228 KSLEDKSLEFKKLSEELAIQLDICCKKTEALLEAKTN--ELINISSSKTNAILS 1279
Score = 33.9 bits (74), Expect = 1.4
Identities = 51/270 (18%), Positives = 116/270 (42%), Gaps = 26/270 (9%)
Query: 268 VEEKLSEI-KEKDENFKQEIDMLNEKLICDRREFNETM-QEKNILLSDLSKKVNKT---- 321
++E+L E+ K KD + ++ ++ + + D + E + Q+K +++++ +++++T
Sbjct: 354 LDERLQELEKIKDLHMAEKTKLITQ--LRDAKNLIEQLEQDKGMVIAETKRQMHETLEMK 411
Query: 322 ERE---LEEKQEQLTHLMEQLNDTENNSYK-LIENMFNKVSQIASDFKISNQLSCELDD- 376
E E L + +Q+T E+L + + S + E + +S + +L E+D+
Sbjct: 412 EEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMDEQ 471
Query: 377 ----ESENTYERISL--TLDKITNHITYL-----NTQINETQKNDNAQLLWEAKKQIADL 425
E + ERISL L ++ + + QI + QK +L + ++ L
Sbjct: 472 IKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKL 531
Query: 426 TEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD--SSTXXXXXXXXXXXXSN 483
+ +E++ +++ ++I + E + L +
Sbjct: 532 QTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQ 591
Query: 484 EIEDMKTKVMEWKSQFEDLDDVMKQQQKEL 513
E E +T+++E +S E K Q K+L
Sbjct: 592 EAETYRTRILELESSLEKSLQENKNQSKDL 621
Score = 33.1 bits (72), Expect = 2.4
Identities = 48/225 (21%), Positives = 96/225 (42%), Gaps = 14/225 (6%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK----NILLS 312
I LE+ K M++ E ++ E E ++EI L ++ + E ++K
Sbjct: 386 IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE 445
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK---LIENMFNKVSQIASDF--KIS 367
+L K ++ ++ E +++ + EQ+ E S + ++ ++V Q D K S
Sbjct: 446 ELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 505
Query: 368 NQLSCELD--DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQL-LWEAKKQIAD 424
+ +L E E + LT T + +K+ + L + + K+Q
Sbjct: 506 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQES 565
Query: 425 LTEQNIILKERLSQLETENK--ELLIEIQTVRGSNEEVTLNLKDS 467
L + + L+++ E+ENK +L E +T R E+ +L+ S
Sbjct: 566 LALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 610
>AB040957-1|BAA96048.1| 884|Homo sapiens KIAA1524 protein protein.
Length = 884
Score = 49.2 bits (112), Expect = 3e-05
Identities = 42/200 (21%), Positives = 92/200 (46%), Gaps = 10/200 (5%)
Query: 323 RELEEKQEQLTHLMEQLNDTENNSYKLIENMF---NKVSQIASDFKISNQLSCELDDESE 379
RE+E K E+L+ L++ + IE++F K+ +A + +I + EL +E
Sbjct: 659 REVERKNEELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNE 718
Query: 380 NTYER---ISLTLDKITNHI---TYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILK 433
+T ++ + +T D + I LN + E + AQL+ E ++Q ++ Q + +
Sbjct: 719 STEKKNKDLQITCDSLNKQIETVKKLNESLKEQNEKSIAQLI-EKEEQRKEVQNQLVDRE 777
Query: 434 ERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVM 493
+L+ L + K +I+T++ E+ + S + ++ +
Sbjct: 778 HKLANLHQKTKVQEEKIKTLQKEREDKEETIDILRKELSRTEQIRKELSIKASSLEVQKA 837
Query: 494 EWKSQFEDLDDVMKQQQKEL 513
+ + + E+ + ++K QQ+EL
Sbjct: 838 QLEGRLEEKESLVKLQQEEL 857
Score = 41.9 bits (94), Expect = 0.005
Identities = 45/181 (24%), Positives = 85/181 (46%), Gaps = 22/181 (12%)
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFE--QLNNAVDKQN------C--IQEEVDLLK 226
++DI L + LESV E+ + E Q N + +K+N C + ++++ +K
Sbjct: 683 QSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNKDLQITCDSLNKQIETVK 742
Query: 227 IENQNLLQXXXXXXXXXXXXXXXXXA-------RDKFIANLEEMKTMLVEEKLSEIKEKD 279
N++L + R+ +ANL + KT + EEK+ ++++
Sbjct: 743 KLNESLKEQNEKSIAQLIEKEEQRKEVQNQLVDREHKLANLHQ-KTKVQEEKIKTLQKER 801
Query: 280 ENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQL 339
E+ ++ ID+L ++L R E + +E +I S L + + E LEEK+ + E+L
Sbjct: 802 EDKEETIDILRKEL--SRTE--QIRKELSIKASSLEVQKAQLEGRLEEKESLVKLQQEEL 857
Query: 340 N 340
N
Sbjct: 858 N 858
Score = 35.5 bits (78), Expect = 0.46
Identities = 46/260 (17%), Positives = 101/260 (38%), Gaps = 15/260 (5%)
Query: 146 EVALEIDLKKNSITKDNISIKTLL----DKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E+ L K S +D + K L D+LI ++ + + L S+ E N
Sbjct: 606 EMKLSTLASKESRLQDLLETKALALAQADRLIAQHRCQRTQAETEARTLASMLREVERKN 665
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
E+L L + Q +++ L N+ L + +
Sbjct: 666 EELSVLLKAQQVESERAQSDIEHLFQHNRKLESVAEEHEILTKSYMELLQRNESTEKKNK 725
Query: 262 EMKTML--VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVN 319
+++ + +++ +K+ +E+ K++ NEK I E E +E L D K+
Sbjct: 726 DLQITCDSLNKQIETVKKLNESLKEQ----NEKSIAQLIEKEEQRKEVQNQLVDREHKLA 781
Query: 320 KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI-SNQL---SCELD 375
++ + ++E++ L ++ D E + ++ ++ QI + I ++ L +L+
Sbjct: 782 NLHQKTKVQEEKIKTLQKEREDKE-ETIDILRKELSRTEQIRKELSIKASSLEVQKAQLE 840
Query: 376 DESENTYERISLTLDKITNH 395
E + L +++ H
Sbjct: 841 GRLEEKESLVKLQQEELNKH 860
>AB033038-1|BAA86526.2| 802|Homo sapiens KIAA1212 protein protein.
Length = 802
Score = 49.2 bits (112), Expect = 3e-05
Identities = 77/331 (23%), Positives = 132/331 (39%), Gaps = 23/331 (6%)
Query: 182 ELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXX 241
E+ + L++ K T ++L Q NN + +Q + L+ +N L
Sbjct: 9 EVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV 68
Query: 242 XXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDML---NEKL-ICDR 297
+ A L ++ L E S IKE+ E+ K D L +EKL +
Sbjct: 69 ENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKER-EDLKSLYDSLIKDHEKLELLHE 127
Query: 298 REFNE--TMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMF- 354
R+ +E ++ K+ L K + R+LE++ QL QL D E E M
Sbjct: 128 RQASEYESLISKHGTLKSAHKNLEVEHRDLEDRYNQLLKQKGQLEDLEKMLKVEQEKMLL 187
Query: 355 -NKVSQ-IASDFKISNQLSCELDDESENTYERISLTLDKI-TNHITYL----NTQINETQ 407
NK + +A+++K C +D +TY ++ + + T+H N+++ +T+
Sbjct: 188 ENKNHETVAAEYK----KLCGENDRLNHTYSQLLKETEVLQTDHKNLKSLLNNSKLEQTR 243
Query: 408 KNDNAQLLWEAKKQI----ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLN 463
L E +Q+ L Q +L + LE EN+ LL +IQT+ N +
Sbjct: 244 LEAEFSKLKEQYQQLDITSTKLNNQCELLSQLKGNLEEENRHLLDQIQTLMLQNRTLLEQ 303
Query: 464 LKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
+S NE+ K K+ E
Sbjct: 304 NMESKDLFHVEQRQYIDKLNELRRQKEKLEE 334
Score = 31.5 bits (68), Expect = 7.4
Identities = 21/101 (20%), Positives = 47/101 (46%), Gaps = 3/101 (2%)
Query: 417 EAKKQIADLTEQNIILKERLSQLETENKEL---LIEIQTVRGSNEEVTLNLKDSSTXXXX 473
E ++ A L + LK +L QLET+N L ++ +Q S +E L+ +
Sbjct: 9 EVERNNATLQAEKQALKTQLKQLETQNNNLQAQILALQRQTVSLQEQNTTLQTQNAKLQV 68
Query: 474 XXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
S + + +++ +S E+ ++ + +++++LK
Sbjct: 69 ENSTLNSQSTSLMNQNAQLLIQQSSLENENESVIKEREDLK 109
>BC103765-1|AAI03766.1| 691|Homo sapiens NUMA1 protein protein.
Length = 691
Score = 48.8 bits (111), Expect = 5e-05
Identities = 67/408 (16%), Positives = 166/408 (40%), Gaps = 20/408 (4%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+SLT ++ + L+ ++D K N ++++N + L + + + + L
Sbjct: 286 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
+ E+ +L ++L+ A+ + C++E+ ++L+ + L +
Sbjct: 346 EEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEK 405
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
+ L++ L ++++ + E + E KL+ +R F E Q+
Sbjct: 406 GEVLGDVLQLETLKQEAATLAANN-TQLQARVEMLETERGQQEAKLLAERGHFEEEKQQL 464
Query: 308 NILLSDLSKKV---NKTERELEEKQE----QLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
+ L++DL + ++ + ELE+ + +LT + L I+ +++ +
Sbjct: 465 SSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGL 524
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKK 420
K + + E + + ++++++ + Q+ E + A A++
Sbjct: 525 KQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQ 584
Query: 421 QIADLTEQNIILKER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSS-TXXXXXXX 476
E+ L+ER L QLE KE +++ ++ +V +DS+ T
Sbjct: 585 LATAAEEREASLRERDAALKQLEALEKEKAAKLEILQ-QQLQVANEARDSAQTSVTQAQR 643
Query: 477 XXXXXSNEIEDMKTKV-------MEWKSQFEDLDDVMKQQQKELKLGK 517
S ++E+++ V E ++Q +L+ ++ +Q++ K K
Sbjct: 644 EKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKAKKKK 691
Score = 41.5 bits (93), Expect = 0.007
Identities = 61/354 (17%), Positives = 146/354 (41%), Gaps = 19/354 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
L++L KNE+ L ++K + +K+E + + K+ + D ++E L+
Sbjct: 278 LEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQL 337
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFI-ANLEEMKTM-----LVEEKLSEIKEKDENF 282
L + +K + A L++ K + +++ KLS+++E
Sbjct: 338 QDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQL 397
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
+ +++ D + QE L ++ ++ + E E+ +Q L+ +
Sbjct: 398 QDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHF 457
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQ 402
E + + + ++ + S +Q EL+ S+ R++ + +T+ +T LN
Sbjct: 458 EEEK----QQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNAT 513
Query: 403 INETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL 462
I + Q + A L +AK++ A L + L Q E ++ L +++ + S ++
Sbjct: 514 IQQ-QDQELAGLKQQAKEKQAQLA-------QTLQQQEQASQGLRHQVEQLSSSLKQKEQ 565
Query: 463 NLKD-SSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
LK+ + + E+ + + E + + L+ + K++ +L++
Sbjct: 566 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEI 619
>BC027493-1|AAH27493.1| 691|Homo sapiens Unknown (protein for
IMAGE:4540541) protein.
Length = 691
Score = 48.8 bits (111), Expect = 5e-05
Identities = 67/408 (16%), Positives = 166/408 (40%), Gaps = 20/408 (4%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+SLT ++ + L+ ++D K N ++++N + L + + + + L
Sbjct: 286 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
+ E+ +L ++L+ A+ + C++E+ ++L+ + L +
Sbjct: 346 EEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEK 405
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
+ L++ L ++++ + E + E KL+ +R F E Q+
Sbjct: 406 GEVLGDVLQLETLKQEAATLAANN-TQLQARVEMLETERGQQEAKLLAERGHFEEEKQQL 464
Query: 308 NILLSDLSKKV---NKTERELEEKQE----QLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
+ L++DL + ++ + ELE+ + +LT + L I+ +++ +
Sbjct: 465 SSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGL 524
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKK 420
K + + E + + ++++++ + Q+ E + A A++
Sbjct: 525 KQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQ 584
Query: 421 QIADLTEQNIILKER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSS-TXXXXXXX 476
E+ L+ER L QLE KE +++ ++ +V +DS+ T
Sbjct: 585 LATAAEEREASLRERDAALKQLEALEKEKAAKLEILQ-QQLQVANEARDSAQTSVTQAQR 643
Query: 477 XXXXXSNEIEDMKTKV-------MEWKSQFEDLDDVMKQQQKELKLGK 517
S ++E+++ V E ++Q +L+ ++ +Q++ K K
Sbjct: 644 EKAELSRKVEELQACVETARQEQHEAQAQVAELELQLRSEQQKAKKKK 691
Score = 41.5 bits (93), Expect = 0.007
Identities = 61/354 (17%), Positives = 146/354 (41%), Gaps = 19/354 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
L++L KNE+ L ++K + +K+E + + K+ + D ++E L+
Sbjct: 278 LEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQL 337
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFI-ANLEEMKTM-----LVEEKLSEIKEKDENF 282
L + +K + A L++ K + +++ KLS+++E
Sbjct: 338 QDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQL 397
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
+ +++ D + QE L ++ ++ + E E+ +Q L+ +
Sbjct: 398 QDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHF 457
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQ 402
E + + + ++ + S +Q EL+ S+ R++ + +T+ +T LN
Sbjct: 458 EEEK----QQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNAT 513
Query: 403 INETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL 462
I + Q + A L +AK++ A L + L Q E ++ L +++ + S ++
Sbjct: 514 IQQ-QDQELAGLKQQAKEKQAQLA-------QTLQQQEQASQGLRHQVEQLSSSLKQKEQ 565
Query: 463 NLKD-SSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
LK+ + + E+ + + E + + L+ + K++ +L++
Sbjct: 566 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEI 619
>AB015617-1|BAA88763.1| 948|Homo sapiens ELKS protein.
Length = 948
Score = 48.8 bits (111), Expect = 5e-05
Identities = 100/473 (21%), Positives = 200/473 (42%), Gaps = 39/473 (8%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
+TV E+K+ +I+SM R L + E + ++K++ E S + +
Sbjct: 381 QTVIEMKDSKISSMERGLRDLEEEIQMLK---SNGALSTEEREEEMKQM-EVYRSHSKFM 436
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSIT-KDNIS--I 165
K + Q+ E++ +L + TLTN F ++ I++ K S+T K+ + +
Sbjct: 437 KNKIGQVKQELSRKDTELL-ALQTKLETLTNQFSDSKQ---HIEVLKESLTAKEQRAAIL 492
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLL 225
+T +D L + E L K ++ + E T ++ + L + +D + + +V++L
Sbjct: 493 QTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHD-LKDMLDVK---ERKVNVL 548
Query: 226 KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQE 285
+ + +NL + + N + T L EE L+E + E K++
Sbjct: 549 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL-EEALAEKERTIERLKEQ 607
Query: 286 IDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN 345
D D RE E + L DL +KV+ + +L EK+ L L E + ++
Sbjct: 608 RDR-------DEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS 660
Query: 346 SYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
K + K +IA + K L E + + + ++++ I +L +I
Sbjct: 661 GLKKDSRL--KTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI-- 716
Query: 406 TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL----IEIQTVRGSNEEVT 461
T+ D + +A+ ++ L E ILKE ++ ++K++ + + V+ N++V
Sbjct: 717 TRYKDESS---KAQAEVDRLLE---ILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVA 770
Query: 462 LNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
NLK + ED + + Q E+L M++ ++EL+
Sbjct: 771 -NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQ-QLQVEELLMAMEKVKQELE 821
Score = 44.0 bits (99), Expect = 0.001
Identities = 66/358 (18%), Positives = 141/358 (39%), Gaps = 17/358 (4%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++LEE+ L I+ +K ++ + SIK LL+ L +K + + + ++E + +
Sbjct: 286 KTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHH 345
Query: 202 -EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L EQ +K+N + E + EN + ++ + +L
Sbjct: 346 LESLLEQ----KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDL 401
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDR-REFNETMQEKNILLSDLSKKV 318
EE ML +E++E KQ E+ + K + ++ + + + K+ L L K+
Sbjct: 402 EEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKL 461
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ + ++ + L E L E + L + ++ + N+ + ++ D +
Sbjct: 462 ETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA 521
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
E + + + + + ++N QK + ++Q+ D +Q LKER+
Sbjct: 522 EEKGTQAG-EIHDLKDMLDVKERKVNVLQKK-----IENLQEQLRDKEKQMSSLKERVKS 575
Query: 439 LE---TENKELLIEIQTVRGSNEEVTLNLKDS-STXXXXXXXXXXXXSNEIEDMKTKV 492
L+ T L ++ E LK+ +++D+K KV
Sbjct: 576 LQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKV 633
Score = 42.7 bits (96), Expect = 0.003
Identities = 75/436 (17%), Positives = 165/436 (37%), Gaps = 35/436 (8%)
Query: 80 LTEKLTIAETKHNDLKKLYEDS---ASELEALKRENIQMHTSDVMVVPEIIDSLTEVINT 136
L EK T+ K ++ + E+ A E+ LK + + + V V+ + I++L E +
Sbjct: 503 LEEKETMLNKKTKQIQDMAEEKGTQAGEIHDLK-DMLDVKERKVNVLQKKIENLQEQLRD 561
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
SL+E + + T + ++ TL + L K T +E +K +
Sbjct: 562 KEKQMSSLKE---RVKSLQADTTNTDTALTTLEEALAEKERT-----------IERLKEQ 607
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
+ + E+++N ++E+V LL+ + +D
Sbjct: 608 RDRDEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASSGLKKDSR 667
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
+ LE + +E+K E + + K+ + E E ++ +Q L +
Sbjct: 668 LKTLE----IALEQKKEECLKMESQLKKAHEAALEARASP--EMSDRIQH-------LER 714
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
++ + + E + Q ++ L+E L + EN + + S + K N+ L
Sbjct: 715 EITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVANLKH 774
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERL 436
+ + ++ + L++ LN + Q + + + K+++ + + ++ L
Sbjct: 775 KEQVEKKKSAQMLEEARRREDNLNDSSQQLQVEELLMAMEKVKQELESMKAKLSSTQQSL 834
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWK 496
++ ET L ++ R + E L +K + E+ K K E
Sbjct: 835 AEKETH----LTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEV 890
Query: 497 SQFEDLDDVMKQQQKE 512
+ + D + QQ K+
Sbjct: 891 AALKREKDRLVQQLKQ 906
Score = 40.7 bits (91), Expect = 0.012
Identities = 52/246 (21%), Positives = 96/246 (39%), Gaps = 10/246 (4%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
+ ++ + EI K+ +K + LL+ ++ + E + N+ I LES+ S
Sbjct: 707 DRIQHLEREITRYKDESSKAQAEVDRLLE-ILKEVENEKNDKDKKIAELESLTSRQVKDQ 765
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
K ++ N K+ ++++ +E + A +K LE
Sbjct: 766 NK---KVANLKHKEQ-VEKKKSAQMLEEARRREDNLNDSSQQLQVEELLMAMEKVKQELE 821
Query: 262 EMKTML--VEEKLSEIKEKDENFKQEIDM-LNEKLICDRREFNETMQEK--NILLSDLSK 316
MK L ++ L+E + N + E L E L + + EK NI L +LS
Sbjct: 822 SMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSS 881
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
KT+ E+ + + L++QL N KL+ + + +S +N D
Sbjct: 882 SKKKTQEEVAALKREKDRLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQD 941
Query: 377 ESENTY 382
E E +
Sbjct: 942 EEEGIW 947
>M21665-1|AAA36345.1| 524|Homo sapiens protein ( Human beta-myosin
heavy chain mRNA, 3' end. ).
Length = 524
Score = 48.4 bits (110), Expect = 6e-05
Identities = 67/344 (19%), Positives = 140/344 (40%), Gaps = 16/344 (4%)
Query: 103 SELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL----EEVALEIDLKKNSI 158
S LE K +Q D+MV E ++ ++ F+ + ++ E + S
Sbjct: 1 SSLEKTKHR-LQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESS 59
Query: 159 TKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCI 218
K+ S+ T L KL E + L + ++++ E + E+L + + +
Sbjct: 60 QKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSS-GKTIHELEKV 118
Query: 219 QEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXAR-DKFIANLEEMKTMLVEEKLSEIKE 277
+++++ K+E Q+ L+ ++ A +E V EK E+++
Sbjct: 119 RKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERN----VAEKDEEMEQ 174
Query: 278 KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK---KVNKTERELEEKQEQLTH 334
N + +D L L + R NE ++ K + DL++ +++ R E Q+Q+
Sbjct: 175 AKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKS 234
Query: 335 LMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITN 394
L L DT+ + + IA + +N L EL +E E+ +
Sbjct: 235 LQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAEL-EELRAVVEQTERSRKLAEQ 293
Query: 395 HITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
+ + ++ + + N L+ + KK ADL++ ++E + +
Sbjct: 294 ELIETSERV-QLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQE 336
Score = 39.9 bits (89), Expect = 0.021
Identities = 56/311 (18%), Positives = 124/311 (39%), Gaps = 23/311 (7%)
Query: 94 LKKLYEDSASELEALKRE--NIQMHTSDVM----VVPEIIDSLTEVINTL-TNGFE---S 143
LK YE+S LE KRE N+Q SD+ + I L +V L E +
Sbjct: 73 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 132
Query: 144 LEEVALEIDLKKNSITKDNI---SIKTLLDKLITKNETDINEL-RNSIKYLESVKSEYNT 199
LEE ++ ++ I + + IK +++ + + + ++ + RN ++ ++S+++ +
Sbjct: 133 LEEAEASLEHEEGKILRAQLEFNQIKAEIERNVAEKDEEMEQAKRNHLRVVDSLQTSLDA 192
Query: 200 ANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIAN 259
E L + + E L N+ + D +
Sbjct: 193 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 252
Query: 260 LEEMK--TMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK 317
+++K +VE + + ++ + E + ++ +E ET + +L S +
Sbjct: 253 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 312
Query: 318 VN---KTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
+N K + +L + Q ++ +++ + E + K I + + +A + K S L
Sbjct: 313 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITD----AAMMAEELKKEQDTSAHL 368
Query: 375 DDESENTYERI 385
+ +N + I
Sbjct: 369 ERMKKNMEQTI 379
>AL031283-7|CAI21429.1| 647|Homo sapiens forkhead-associated (FHA)
phosphopeptide binding domain 1 protein.
Length = 647
Score = 48.4 bits (110), Expect = 6e-05
Identities = 37/192 (19%), Positives = 96/192 (50%), Gaps = 6/192 (3%)
Query: 268 VEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEE 327
+EE+ + ++E +E ++ ++ + ++R+ E M+++ + DL ++ K + ELE
Sbjct: 12 LEEEQTRVQELEERLARQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEELEL 71
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
K+++ L +L+D + E K ++ ++ +L+ E E E T ++ +
Sbjct: 72 KEQKEDVLNNKLSDA---LAMVEETQKTKATESLKAESLALKLN-ETLAELETTKTKMIM 127
Query: 388 TLDK--ITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKE 445
++ + + E+Q++ + + E K+QI + + L+E+L ++ +K+
Sbjct: 128 VEERLILQQKMVKALQDEQESQRHGFEEEIMEYKEQIKQHAQTIVSLEEKLQKVTQHHKK 187
Query: 446 LLIEIQTVRGSN 457
+ EI T++ ++
Sbjct: 188 IEGEIATLKDND 199
Score = 40.3 bits (90), Expect = 0.016
Identities = 46/210 (21%), Positives = 97/210 (46%), Gaps = 15/210 (7%)
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKL---ICDRREFNETMQEKNILLSDLSKK 317
E+ K +E +L++ KE+ E +Q+ D+LN KL + E +T +++ L+ K
Sbjct: 51 EKKKVQDLENRLTKQKEELELKEQKEDVLNNKLSDALAMVEETQKTKATESLKAESLALK 110
Query: 318 VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDE 377
+N+T ELE + ++ + E+L + K+++ + ++ F+ E +
Sbjct: 111 LNETLAELETTKTKMIMVEERLILQQ----KMVKALQDEQESQRHGFEEEIMEYKEQIKQ 166
Query: 378 SENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQ---IADLTE---QNII 431
T + L K+T H + +I + ND A E + Q +A +TE +++
Sbjct: 167 HAQTIVSLEEKLQKVTQHHKKIEGEIATLKDNDPAPK--EERPQDPLVAPMTESSAKDMA 224
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVT 461
+ + L KE+L + + + +++T
Sbjct: 225 YEHLIDDLLAAQKEILSQQEVIMKLRKDLT 254
Score = 37.9 bits (84), Expect = 0.085
Identities = 74/371 (19%), Positives = 144/371 (38%), Gaps = 35/371 (9%)
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKL 204
E +A + ++ +++I + K ++K K + N L + LE + + + N KL
Sbjct: 24 ERLARQKEISESNIAYEKRKAKEAMEKEKKKVQDLENRLTKQKEELELKEQKEDVLNNKL 83
Query: 205 FEQLNNAVDKQNCIQEE---VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
+ L + Q E + L ++ L + K + L+
Sbjct: 84 SDALAMVEETQKTKATESLKAESLALKLNETLAELETTKTKMIMVEERLILQQKMVKALQ 143
Query: 262 ---EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV 318
E + EE++ E KE+ + Q I L EKL T K I + K
Sbjct: 144 DEQESQRHGFEEEIMEYKEQIKQHAQTIVSLEEKL------QKVTQHHKKIEGEIATLKD 197
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
N + E Q+ L M + + + LI+++ +I S ++ +L +L +
Sbjct: 198 NDPAPKEERPQDPLVAPMTESSAKDMAYEHLIDDLLAAQKEILSQQEVIMKLRKDLTE-- 255
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
+ R+S L ++NE QK + Q + ++Q +L+ +LKE+++Q
Sbjct: 256 --AHSRMS-----------DLRGELNEKQKMELEQNVVLVQQQSKELS----VLKEKMAQ 298
Query: 439 L----ETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
+ E +++EL + +R S E+ L L S +IE + T+
Sbjct: 299 MSSLVEKKDRELKALEEALRASQEKHRLQLNTEKEQKPRKKTQTCDTSVQIEPVHTEAFS 358
Query: 495 WKSQFEDLDDV 505
+ + D+
Sbjct: 359 SSQEQQSFSDL 369
>AF308294-1|AAG48261.1| 312|Homo sapiens serologically defined
breast cancer antigen NY-BR-62 protein.
Length = 312
Score = 48.4 bits (110), Expect = 6e-05
Identities = 57/275 (20%), Positives = 127/275 (46%), Gaps = 31/275 (11%)
Query: 169 LDKLITKNE---TDINELR----NSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEE 221
L + TKN+ +++++LR ++ K L SVK EY++ ++ N ++ +Q +
Sbjct: 1 LQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERHMHVQLQ 60
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE---KLSEIKEK 278
+D L++EN+ LL+ +D + NL+E+ +++ L K++
Sbjct: 61 LDNLRLENEKLLE-------------SKACLQDSY-DNLQEIMKFEIDQLSRNLQNFKKE 106
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT-ERELEEKQEQLTHLME 337
+E K +++ L E L ++ N+ + + SK++ K E +EKQ++ +
Sbjct: 107 NETLKSDLNNLMELLEAEKERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQ 166
Query: 338 QLNDTENNSYKLI--ENMFNKVSQIA-SDFKISNQLSCELDDESENTYERISLTLDKITN 394
Q+ + L+ E + + + + SD K+ L ++ + + E+ T+D +
Sbjct: 167 QMAKVQKLEESLLATEKVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTE-TIDTLKQ 225
Query: 395 HITYLNTQINE--TQKNDNAQLLWEAKKQIADLTE 427
+ +N + N + ++ L+ + + I DL E
Sbjct: 226 ELKDINCKYNSALVDREESRVLIKKQEVDILDLKE 260
>AF273047-1|AAG34907.1| 623|Homo sapiens CTCL tumor antigen se20-7
protein.
Length = 623
Score = 48.4 bits (110), Expect = 6e-05
Identities = 91/442 (20%), Positives = 189/442 (42%), Gaps = 31/442 (7%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEII--DSLTEVINTLTNGFESLEEVALE- 150
L+KL+E + E + +Q + ++ S +E + ++ E E +ALE
Sbjct: 144 LQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLK-ISQEKEQQESLALEE 202
Query: 151 IDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNN 210
++L+K +I ++ + L + T I EL +S LE E ++ L L
Sbjct: 203 LELQKKAILTESENKLRDLQQEAETYRTRILELESS---LEKSLQENKNQSKDLAVHLEA 259
Query: 211 AVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE 270
+K N E+ ++ +++ L+ + ++ +E+++ +E
Sbjct: 260 EKNKHNM---EITVMVEKHKTELESLKHQQDALWTEKLQVL-KQQYQTEMEKLREKCEQE 315
Query: 271 KLSEIKEKDENFKQEIDMLNEKLICDRREFNET-MQEKNILLSDLSKKVNKTERELEEKQ 329
K + +K+K+ F+ I+ +NEK + ++ + +T ++ + LS++ K +K E EL +
Sbjct: 316 KETLLKDKEIIFQAHIEEMNEKTL-EKLDVKQTELESLSSELSEVLKARHKLEEELSVLK 374
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+Q T M+Q + + + K + +V I + ++S Q + + + N E +
Sbjct: 375 DQ-TDKMKQELEAKMDEQK--NHHQQQVDSIIKEHEVSIQRTEKALKDQINQLELLLKER 431
Query: 390 DKITN----HITYLNTQINETQ--------KNDNAQLLWEA-KKQIADLTEQNIILKERL 436
DK H+ L I ++ K D Q A +Q EQ L+++L
Sbjct: 432 DKHLKEHQAHVENLEADIKRSEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKL 491
Query: 437 SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED-MKTKVMEW 495
LETE L ++ V ++V L ++E+E +K+ +
Sbjct: 492 LDLETERILLTKQVAEVEAQKKDVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQVY 551
Query: 496 KSQFEDLDDVMKQQQKELKLGK 517
+S+ ED + ++Q K++ + K
Sbjct: 552 ESKLED-GNKEQEQTKQILVEK 572
Score = 33.1 bits (72), Expect = 2.4
Identities = 48/225 (21%), Positives = 96/225 (42%), Gaps = 14/225 (6%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK----NILLS 312
I LE+ K M++ E ++ E E ++EI L ++ + E ++K
Sbjct: 18 IEQLEQDKGMVIAETKRQMHETLEMKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFE 77
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK---LIENMFNKVSQIASDF--KIS 367
+L K ++ ++ E +++ + EQ+ E S + ++ ++V Q D K S
Sbjct: 78 ELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSS 137
Query: 368 NQLSCELD--DESENTYERISLTLDKITNHITYLNTQINETQKNDNAQL-LWEAKKQIAD 424
+ +L E E + LT T + +K+ + L + + K+Q
Sbjct: 138 EEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQES 197
Query: 425 LTEQNIILKERLSQLETENK--ELLIEIQTVRGSNEEVTLNLKDS 467
L + + L+++ E+ENK +L E +T R E+ +L+ S
Sbjct: 198 LALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKS 242
Score = 31.1 bits (67), Expect = 9.8
Identities = 50/264 (18%), Positives = 107/264 (40%), Gaps = 28/264 (10%)
Query: 264 KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTER 323
KT L+ + L + K E +Q+ M+ + +R+ +ET++ K ++ L ++ +
Sbjct: 4 KTKLITQ-LRDAKNLIEQLEQDKGMVIAET---KRQMHETLEMKEEEIAQLRSRIKQMTT 59
Query: 324 ELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD-----ES 378
+ EE L EQ +E +++ +E + + + +L E+D+ E
Sbjct: 60 QGEE-------LREQKEKSERAAFEELEKALSTAQKTE---EARRKLKAEMDEQIKTIEK 109
Query: 379 ENTYERISL--TLDKITNHITYL-----NTQINETQKNDNAQLLWEAKKQIADLTEQNII 431
+ ERISL L ++ + + QI + QK +L + ++ L +
Sbjct: 110 TSEEERISLQQELSRVKQEVVDVMKKSSEEQIAKLQKLHEKELARKEQELTKKLQTRERE 169
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEEVTLNLKD--SSTXXXXXXXXXXXXSNEIEDMK 489
+E++ +++ ++I + E + L + E E +
Sbjct: 170 FQEQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYR 229
Query: 490 TKVMEWKSQFEDLDDVMKQQQKEL 513
T+++E +S E K Q K+L
Sbjct: 230 TRILELESSLEKSLQENKNQSKDL 253
>Z11584-1|CAA77670.1| 2101|Homo sapiens NuMA protein protein.
Length = 2101
Score = 48.0 bits (109), Expect = 8e-05
Identities = 61/376 (16%), Positives = 151/376 (40%), Gaps = 13/376 (3%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+SLT ++ + L+ ++D K N ++++N + L + + + + L
Sbjct: 286 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
+ E+ +L ++L+ A+ + C++E+ ++L+ + L +
Sbjct: 346 EEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEK 405
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
+ L++ L ++++ + E + E KL+ +R F E Q+
Sbjct: 406 GEVLGDVLQLETLKQEAATLAANN-TQLQARVEMLETERGQQEAKLLAERGHFEEEKQQL 464
Query: 308 NILLSDLSKKV---NKTERELEEKQE----QLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
+ L++DL + ++ + ELE+ + +LT + L I+ +++ +
Sbjct: 465 SSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGL 524
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKK 420
K + + E + + ++++++ + Q+ E + A A++
Sbjct: 525 KQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQ 584
Query: 421 QIADLTEQNIILKER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSS-TXXXXXXX 476
E+ L+ER L QLE KE +++ ++ +V +DS+ T
Sbjct: 585 LATAAEEREASLRERDAALKQLEALEKEKAAKLEILQ-QQLQVANEARDSAQTSVTQAQR 643
Query: 477 XXXXXSNEIEDMKTKV 492
S ++E+++ V
Sbjct: 644 EKAELSRKVEELQACV 659
Score = 41.5 bits (93), Expect = 0.007
Identities = 61/354 (17%), Positives = 146/354 (41%), Gaps = 19/354 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
L++L KNE+ L ++K + +K+E + + K+ + D ++E L+
Sbjct: 278 LEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQL 337
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFI-ANLEEMKTM-----LVEEKLSEIKEKDENF 282
L + +K + A L++ K + +++ KLS+++E
Sbjct: 338 QDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQL 397
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
+ +++ D + QE L ++ ++ + E E+ +Q L+ +
Sbjct: 398 QDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHF 457
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQ 402
E + + + ++ + S +Q EL+ S+ R++ + +T+ +T LN
Sbjct: 458 EEEK----QQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNAT 513
Query: 403 INETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL 462
I + Q + A L +AK++ A L + L Q E ++ L +++ + S ++
Sbjct: 514 IQQ-QDQELAGLKQQAKEKQAQLA-------QTLQQQEQASQGLRHQVEQLSSSLKQKEQ 565
Query: 463 NLKD-SSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
LK+ + + E+ + + E + + L+ + K++ +L++
Sbjct: 566 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEI 619
Score = 39.5 bits (88), Expect = 0.028
Identities = 68/395 (17%), Positives = 153/395 (38%), Gaps = 25/395 (6%)
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
LT+ E EE+ E+ + + ++ TL + T + ++EL + + +++E
Sbjct: 1315 LTSQAERAEELGQELKAWQEKFFQKEQALSTLQLEH-TSTQALVSELLPAKHLCQQLQAE 1373
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
A ++ E+L + ++ E+ + E L+ + +
Sbjct: 1374 QAAAEKRHREELEQSKQAAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASY 1433
Query: 257 IANLEEMKT---MLVEEK--LSEIKEKDENFKQ-EIDMLNEKLICDRREFNETMQEKNIL 310
L +K +L EE L E F + E+D EK + +E +
Sbjct: 1434 AEQLSMLKKAHGLLAEENRGLGERANLGRQFLEVELDQAREKYV---QELAAVRADAETR 1490
Query: 311 LSDLSKKVNKTERELE----EKQEQLTHLMEQLNDTENNSYKL---IENMFNKVSQIASD 363
L+++ ++ T RELE + + ++E+ + KL +E + K++
Sbjct: 1491 LAEVQREAQSTARELEVMTAKYEGAKVKVLEERQRFQEERQKLTAQVEELSKKLADSDQA 1550
Query: 364 FKISNQLSCELD---DESENTYERISLTLDKITNHITYLNTQINETQ-KNDNAQLLWEAK 419
K+ Q + ES+ +R L+++ ++ + + + A+ ++AK
Sbjct: 1551 SKVQQQKLKAVQAQGGESQQEAQRFQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAK 1610
Query: 420 KQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXX 479
KQ ++ + L QL+ ENKEL E + + ++ L K++
Sbjct: 1611 KQQNQELQEQL---RSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVR 1667
Query: 480 XXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
++ ++ + +F+ D +K ++ + K
Sbjct: 1668 SLEAQVAHADQQLRD-LGKFQVATDALKSREPQAK 1701
>Z11583-1|CAA77669.1| 2115|Homo sapiens NuMA protein protein.
Length = 2115
Score = 48.0 bits (109), Expect = 8e-05
Identities = 61/376 (16%), Positives = 151/376 (40%), Gaps = 13/376 (3%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+SLT ++ + L+ ++D K N ++++N + L + + + + L
Sbjct: 286 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 345
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
+ E+ +L ++L+ A+ + C++E+ ++L+ + L +
Sbjct: 346 EEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEK 405
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
+ L++ L ++++ + E + E KL+ +R F E Q+
Sbjct: 406 GEVLGDVLQLETLKQEAATLAANN-TQLQARVEMLETERGQQEAKLLAERGHFEEEKQQL 464
Query: 308 NILLSDLSKKV---NKTERELEEKQE----QLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
+ L++DL + ++ + ELE+ + +LT + L I+ +++ +
Sbjct: 465 SSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGL 524
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKK 420
K + + E + + ++++++ + Q+ E + A A++
Sbjct: 525 KQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQ 584
Query: 421 QIADLTEQNIILKER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSS-TXXXXXXX 476
E+ L+ER L QLE KE +++ ++ +V +DS+ T
Sbjct: 585 LATAAEEREASLRERDAALKQLEALEKEKAAKLEILQ-QQLQVANEARDSAQTSVTQAQR 643
Query: 477 XXXXXSNEIEDMKTKV 492
S ++E+++ V
Sbjct: 644 EKAELSRKVEELQACV 659
Score = 45.2 bits (102), Expect = 6e-04
Identities = 91/509 (17%), Positives = 198/509 (38%), Gaps = 49/509 (9%)
Query: 36 LKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTI--AETKHND 93
L S L++ V + ++ V E + + ++L L E+L + AET N
Sbjct: 1226 LISSLEEEVSILNRQVLEKEGES-----KELKRLVMAESEKSQKLEERLRLLQAETASNS 1280
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDL 153
+ A+E + RE +Q + ++L + LT+ E EE+ E+
Sbjct: 1281 AR------AAERSSALREEVQSLREEAEKQRVASENLRQ---ELTSQAERAEELGQELKA 1331
Query: 154 KKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVD 213
+ + ++ TL + T + ++EL + + +++E A ++ E+L +
Sbjct: 1332 WQEKFFQKEQALSTLQLEH-TSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQ 1390
Query: 214 KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKT---MLVEE 270
++ E+ + E L+ + + L +K +L EE
Sbjct: 1391 AAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEE 1450
Query: 271 K--LSEIKEKDENFKQ-EIDMLNEKLICD---------------RREFNETMQEKNILLS 312
L E F + E+D EK + + +RE T +E ++ +
Sbjct: 1451 NRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTA 1510
Query: 313 DLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
KV + + +E++++LT +EQL + K +E + K++ K+ Q
Sbjct: 1511 KYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQ 1570
Query: 370 LSCELD---DESENTYERISLTLDKITNHITYLNTQINETQ-KNDNAQLLWEAKKQIADL 425
+ ES+ +R+ L+++ ++ + + + A+ ++AKKQ
Sbjct: 1571 KLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQE 1630
Query: 426 TEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEI 485
++ + L QL+ ENKEL E + + ++ L K++ ++
Sbjct: 1631 LQEQL---RSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQV 1687
Query: 486 EDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
++ + +F+ D +K ++ + K
Sbjct: 1688 AHADQQLRD-LGKFQVATDALKSREPQAK 1715
Score = 41.5 bits (93), Expect = 0.007
Identities = 61/354 (17%), Positives = 146/354 (41%), Gaps = 19/354 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
L++L KNE+ L ++K + +K+E + + K+ + D ++E L+
Sbjct: 278 LEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQL 337
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFI-ANLEEMKTM-----LVEEKLSEIKEKDENF 282
L + +K + A L++ K + +++ KLS+++E
Sbjct: 338 QDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQL 397
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
+ +++ D + QE L ++ ++ + E E+ +Q L+ +
Sbjct: 398 QDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHF 457
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQ 402
E + + + ++ + S +Q EL+ S+ R++ + +T+ +T LN
Sbjct: 458 EEEK----QQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNAT 513
Query: 403 INETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL 462
I + Q + A L +AK++ A L + L Q E ++ L +++ + S ++
Sbjct: 514 IQQ-QDQELAGLKQQAKEKQAQLA-------QTLQQQEQASQGLRHQVEQLSSSLKQKEQ 565
Query: 463 NLKD-SSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
LK+ + + E+ + + E + + L+ + K++ +L++
Sbjct: 566 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEI 619
>BC130453-1|AAI30454.1| 1726|Homo sapiens ANKRD26 protein protein.
Length = 1726
Score = 48.0 bits (109), Expect = 8e-05
Identities = 73/374 (19%), Positives = 158/374 (42%), Gaps = 30/374 (8%)
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVD---KQNCIQEE 221
IK+ L+ + E ++ LR S+ E + +T EK+ EQL + K+ ++++
Sbjct: 789 IKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQ 848
Query: 222 VDL--------LKIENQNLLQXXXXXXXXXXXXXXXXXAR---DKFIAN-LEEMKTM-LV 268
++L L+ NL Q AR D + N L + K + +
Sbjct: 849 LELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMA 908
Query: 269 EEKL----SEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
++K+ S E++++ + ML E++ R E +T++ +N + KK + +
Sbjct: 909 QKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEI-DTIKNQN---QEKEKKCFEDLKI 964
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV----SQIASDFKISNQLSCELDDESEN 380
++EK E L ++Q +T + + + + + S + Q L+ E E+
Sbjct: 965 VKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 1024
Query: 381 TYERISLTL-DKITNHITYLNTQINETQKNDNAQLLWEAKK-QIADLTEQNIILKERLSQ 438
+ R++ + D+ + + ++ + D L + +++L + N IL ++L +
Sbjct: 1025 YHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFK 1084
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
E++ L IE R + E TL L+ + ++ + KV ++ +
Sbjct: 1085 TESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGK 1144
Query: 499 FEDLDDVMKQQQKE 512
E +++ + Q Q E
Sbjct: 1145 QESVEERLSQLQSE 1158
Score = 37.5 bits (83), Expect = 0.11
Identities = 45/214 (21%), Positives = 96/214 (44%), Gaps = 18/214 (8%)
Query: 178 TDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDL-------LKIENQ 230
++ N L+ E+ K+E +L ++L + + KQ+ + +++ L+ E Q
Sbjct: 1214 SECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQ 1273
Query: 231 NLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE----KLSEIKEKDENFKQEI 286
+L + + +++ K L ++ K++ K+ D+ + +
Sbjct: 1274 DLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQK 1333
Query: 287 DMLNEKLICDRRE-FNETMQEKNILLSDLSKKVNKT---ERELEEKQEQLTHLMEQLNDT 342
++LN L D +E + M+ K L +L +++ K ERE+ + L ++LN+
Sbjct: 1334 NLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEY 1393
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
EN + ++ K SQ D +I N+L ++DD
Sbjct: 1394 ENGEFSFHGDL--KTSQFEMDIQI-NKLKHKIDD 1424
Score = 36.3 bits (80), Expect = 0.26
Identities = 53/261 (20%), Positives = 106/261 (40%), Gaps = 16/261 (6%)
Query: 266 MLVEEKLSEIKEKDENFK-QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
+L+E+ E K+ K Q+ + E+L+ ++ E + K + + KVN +RE
Sbjct: 726 LLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVK---IKKMEDKVNVLQRE 782
Query: 325 LEEKQEQLTHLMEQLNDTENN--SYKLIENMFNKVSQIASDF--KISNQLSCELDD--ES 378
L E +E + L Q + E S + N + + A KI QL + + +
Sbjct: 783 LSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKE 842
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
+++ L+L + + + + +N+ + N +++Q A + + I+ Q
Sbjct: 843 VEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQ 902
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDS--STXXXXXXXXXXXXSNEIEDMKTKVME-- 494
E E + + + EE L+ K+S N+ ++ + K E
Sbjct: 903 KEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDL 962
Query: 495 --WKSQFEDLDDVMKQQQKEL 513
K + EDL +KQ ++ L
Sbjct: 963 KIVKEKNEDLQKTIKQNEETL 983
Score = 33.5 bits (73), Expect = 1.8
Identities = 59/321 (18%), Positives = 127/321 (39%), Gaps = 43/321 (13%)
Query: 150 EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLN 209
EI++ + + +N L KN E+ ++++K++ +K FE L
Sbjct: 904 EIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLK 963
Query: 210 NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
+K +Q+ + K + L Q + ++
Sbjct: 964 IVKEKNEDLQKTI---KQNEETLTQTISQYNGRLSVLTA---------------ENAMLN 1005
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
KL K+ E + E++ + +L + +++ K +L + E Q
Sbjct: 1006 SKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKR----ELELAFQRARDECSRLQ 1061
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+++ + L D N+ L + +F S++ N L E + E+ +L L
Sbjct: 1062 DKMNFDVSNLKD---NNEILSQQLFKTESKL-------NSLEIEFHHTRDALREK-TLGL 1110
Query: 390 DKITNHITYLNTQINE-TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETEN---KE 445
+++ ++ Q+ E QK N Q+ + K I ++++ +ERLSQL++EN ++
Sbjct: 1111 ERVQKDLSQTQCQMKEMEQKYQNEQV--KVNKYIG--KQESV--EERLSQLQSENMLLRQ 1164
Query: 446 LLIEIQTVRGSNEEVTLNLKD 466
L + + E+ +N++D
Sbjct: 1165 QLDDAHNKADNKEKTVINIQD 1185
Score = 31.5 bits (68), Expect = 7.4
Identities = 52/270 (19%), Positives = 105/270 (38%), Gaps = 15/270 (5%)
Query: 255 KFIANLEEMKTMLVE---EKLSE-IKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL 310
+F N EE K + EK+ E ++ K+E +++E+++ ++L + ++
Sbjct: 808 RFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEV-KQQLELSLQTLEMELRTVKSN 866
Query: 311 LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQL 370
L+ + ++ N +R+L +Q L + + + K IE K++ S+ S++
Sbjct: 867 LNQVVQERNDAQRQLSREQNARM-LQDGILTNHLSKQKEIEMAQKKMN---SENSHSHEE 922
Query: 371 SCELDDESENTYERIS---LTLDKITNHITYLNTQINETQK---NDNAQLLWEAKKQIAD 424
+L ++ E I+ L +D I N + E K N L K+
Sbjct: 923 EKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEET 982
Query: 425 LTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNE 484
LT+ RLS L EN L +++ + S E + ++ +
Sbjct: 983 LTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETS 1042
Query: 485 IEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++ + + L D M LK
Sbjct: 1043 KRELELAFQRARDECSRLQDKMNFDVSNLK 1072
>BC011621-1|AAH11621.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 48.0 bits (109), Expect = 8e-05
Identities = 105/501 (20%), Positives = 198/501 (39%), Gaps = 48/501 (9%)
Query: 35 QLKSGLQQ-NVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHND 93
QLK L++ + +K + +E++ + L + EKL + +D
Sbjct: 179 QLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDD 238
Query: 94 ----LKKLYEDSASELEALKRENIQMHTS--DVMV-VPEIIDSLTEVINT---LTNGFES 143
+ K Y + +LE L+ EN ++ + D V E+ L E + LT+ E
Sbjct: 239 PNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEE 298
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
+ EID+ + + K N T+ ++ + D+N+LR +K L+ Y
Sbjct: 299 TRALKDEIDVLRATSDKANKLESTV--EIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVS 356
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNL-LQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
L E+L K N + +++ K + Q+L ++ +K A L+E
Sbjct: 357 LEEELK----KANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKE 412
Query: 263 MKTMLVEEK--LSEIKEKDENFKQEIDMLN---------------EKLICDRREFNETMQ 305
K L+E++ L E E+ + + D LN E + + RE +Q
Sbjct: 413 -KERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQ 471
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
+N +L L ++ ++ ER +EE QEQL ++N+ E +L + ++ Q D +
Sbjct: 472 HENKMLR-LQQEGSENER-IEELQEQLEQKHRKMNELETEQ-RLSKERIRELQQQIEDLQ 528
Query: 366 ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDN--AQLLWEAKKQIA 423
S Q E +SE E S K+ H+ L E QK L + + +
Sbjct: 529 KSLQ---EQGSKSEG--ESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQ 583
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
+ E L+++ ++ + + ++ R + + L +S
Sbjct: 584 KINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKER 643
Query: 484 EIE--DMKTKVMEWKSQFEDL 502
IE + + KV +++ E L
Sbjct: 644 RIEILESECKVAKFRDYEEKL 664
>AY517555-1|AAT44528.1| 941|Homo sapiens hypothetical
rhabdomyosarcoma antigen MU-RMS-40.3 protein.
Length = 941
Score = 48.0 bits (109), Expect = 8e-05
Identities = 69/363 (19%), Positives = 150/363 (41%), Gaps = 25/363 (6%)
Query: 81 TEKLTIAETKHNDLKKLYEDSASELEALK---------RENIQMHTSDVMVVPEIIDSLT 131
TE+L A+ K L + +DS ++EA+ ++ +Q D+MV E +SL
Sbjct: 385 TEELEEAKKK---LAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANSLA 441
Query: 132 EVINTLTNGFESL----EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
++ F+ + + E + + K++ S+ T L KL E +++L
Sbjct: 442 AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLETVK 501
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
+ ++++ E E++ E + + +++++L K + Q L+
Sbjct: 502 RENKNLEQEIADLTEQIAEN-GKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKI 560
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
+ + + K + EK EI++ N+++ ++ + L + R NE ++ K
Sbjct: 561 LRIQLELTQVKSEIDRK---IAEKDEEIEQLKRNYQRTVETMQSALDAEVRSRNEAIRLK 617
Query: 308 NILLSDLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDF 364
+ DL++ +++ R+ E + L + QL DT+ + + + Q+A
Sbjct: 618 KKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVE 677
Query: 365 KISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIAD 424
+ +N L E+ +E T E+ + N ++ + N L+ KK D
Sbjct: 678 RRANLLQAEV-EELRATLEQTERARKLAEQELLDSNERV-QLLHTQNTSLIHTKKKLETD 735
Query: 425 LTE 427
L +
Sbjct: 736 LMQ 738
Score = 46.4 bits (105), Expect = 2e-04
Identities = 93/499 (18%), Positives = 196/499 (39%), Gaps = 34/499 (6%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
F+ +++E I +L+ ++ KT E + + + +L
Sbjct: 106 FQKKIKELQARIEELEEEIEAERATRAKT--EKQRSDYARELEELSERLEEAGGVTSTQI 163
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
E E + L++ E++ + EA+ + H V + E ID+L V L
Sbjct: 164 ELNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLE--- 220
Query: 142 ESLEEVALEID---LKKNSITKDNISIKTL---LDKLITKNETDINELRNSIKYLESVKS 195
+ E LEID S++K +++ + L+ +++ E++ S+ L + KS
Sbjct: 221 KEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKS 280
Query: 196 EYNTANEKLFEQLNN--------AVDKQNCIQEEVDLLK-IENQNLLQXXXXXXXXXXXX 246
T +L QL + KQ Q+ +L + +E +N +
Sbjct: 281 RLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRH 340
Query: 247 XXXXXARDKFIANLE---EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
R+++ E E++ L + SE+ + ++ + E+L +++ +
Sbjct: 341 DCDLL-REQYEEEQEGKAELQRALSKAN-SEVAQWRTKYETDAIQRTEELEEAKKKLAQR 398
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
+Q+ + ++ K E+ + Q ++ LM + + N+ ++ ++ ++
Sbjct: 399 LQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDV-ERANSLAAALDKKQRNFDKVLAE 457
Query: 364 FKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIA 423
+K + S + S +S L K+ N Q+ ET K +N L +++IA
Sbjct: 458 WKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQL-ETVKRENKNL----EQEIA 512
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
DLTEQ + + +LE K++ +E ++ + EE L+ +
Sbjct: 513 DLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKS 572
Query: 484 EIEDMKTKVMEWKSQFEDL 502
EI+ K+ E + E L
Sbjct: 573 EID---RKIAEKDEEIEQL 588
Score = 44.4 bits (100), Expect = 0.001
Identities = 61/278 (21%), Positives = 117/278 (42%), Gaps = 22/278 (7%)
Query: 255 KFIANLEEMKTMLVEE-KLSEIKEKD-ENFKQEIDMLNEKLICDRREFNETMQEKNILLS 312
K +LE K L + KL++ D EN KQ++D +K + + ++++ L
Sbjct: 45 KLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGL 104
Query: 313 DLSKKVNKTERELEEKQEQL-------THLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
KK+ + + +EE +E++ +Q +D +L E + ++ +
Sbjct: 105 QFQKKIKELQARIEELEEEIEAERATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIE 164
Query: 366 ISNQLSCEL-----D-DESENTYERISLTL-DKITNHITYLNTQINETQ--KNDNAQLLW 416
++ + E D +E+ +E + TL K + + L QI+ Q K +
Sbjct: 165 LNKKREAEFLKLRRDLEEATLQHEAMVATLRKKHADSVAELGEQIDNLQRVKQKLEKEKS 224
Query: 417 EAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXX 476
E K +I DL+ + + + LE + L ++ RG NEE+ +L + +T
Sbjct: 225 EFKLEIDDLSSSMESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQT 284
Query: 477 XXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
S ++E+ ++ V SQ QQ +ELK
Sbjct: 285 EAGELSRQLEEKESIV----SQLSRSKQAFTQQTEELK 318
Score = 39.1 bits (87), Expect = 0.037
Identities = 74/426 (17%), Positives = 181/426 (42%), Gaps = 37/426 (8%)
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFES--LEEVALEI 151
LK YE++ +LE +KREN + ++ + E I + I+ L + LE+ +++
Sbjct: 486 LKNAYEEALDQLETVKRENKNLE-QEIADLTEQIAENGKTIHELEKSRKQIELEKADIQL 544
Query: 152 DLKKNSITKDNISIKTLLDKL-ITKNETDIN-ELRNSIKYLESVKSEYNTANEKLFEQLN 209
L++ ++ K L +L +T+ +++I+ ++ + +E +K Y ++ E +
Sbjct: 545 ALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLKRNY----QRTVETMQ 600
Query: 210 NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
+A+D + + E LK + + L + +L ++ L +
Sbjct: 601 SALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAET------LKHLRSVQGQLKD 654
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRRE--FNETMQEKNILLSDLSKKVNKTERELEE 327
+L D+ + + D+ + I +RR ++E L + E+EL +
Sbjct: 655 TQL----HLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQELLD 710
Query: 328 KQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISL 387
E++ L+ N + ++ K +E + Q+ S+ + +++ + +++++ ++
Sbjct: 711 SNERV-QLLHTQNTSLIHTKKKLET---DLMQLQSEVEDASRDARNAEEKAKKAITDAAM 766
Query: 388 TLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIIL--KERLSQLETENKE 445
+++ +T + + N + + + D EQ + K+++ +LET +E
Sbjct: 767 MAEELKKE---QDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRE 823
Query: 446 LLIEIQTVRGSNEEVTLNL-------KDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
L E++ + N E L K+ + + ++ ++ KV +K Q
Sbjct: 824 LEFELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQ 883
Query: 499 FEDLDD 504
E+ D+
Sbjct: 884 AEEADE 889
Score = 33.9 bits (74), Expect = 1.4
Identities = 58/231 (25%), Positives = 97/231 (41%), Gaps = 34/231 (14%)
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLN----DTENNSYKL----------IENMFNKVS 358
D +NKT+ +LE++ E L +EQ D E N KL I ++ N
Sbjct: 17 DKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQ 76
Query: 359 QIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEA 418
Q+ K + C+L + E+ + + L K I L +I E ++ A+ A
Sbjct: 77 QLDERLKKKDFEYCQLQSKVEDE-QTLGLQFQK---KIKELQARIEELEEEIEAERATRA 132
Query: 419 K--KQIADLTEQNIILKERL--------SQLETENKELLIEIQTVRGSNEEVTLNLKDS- 467
K KQ +D + L ERL +Q+E NK+ E +R EE TL +
Sbjct: 133 KTEKQRSDYARELEELSERLEEAGGVTSTQIEL-NKKREAEFLKLRRDLEEATLQHEAMV 191
Query: 468 STXXXXXXXXXXXXSNEIEDM---KTKVMEWKSQFE-DLDDVMKQQQKELK 514
+T +I+++ K K+ + KS+F+ ++DD+ + K
Sbjct: 192 ATLRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSK 242
>AL162272-4|CAC19649.1| 1710|Homo sapiens novel protein protein.
Length = 1710
Score = 48.0 bits (109), Expect = 8e-05
Identities = 73/374 (19%), Positives = 158/374 (42%), Gaps = 30/374 (8%)
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVD---KQNCIQEE 221
IK+ L+ + E ++ LR S+ E + +T EK+ EQL + K+ ++++
Sbjct: 773 IKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQ 832
Query: 222 VDL--------LKIENQNLLQXXXXXXXXXXXXXXXXXAR---DKFIAN-LEEMKTM-LV 268
++L L+ NL Q AR D + N L + K + +
Sbjct: 833 LELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMA 892
Query: 269 EEKL----SEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
++K+ S E++++ + ML E++ R E +T++ +N + KK + +
Sbjct: 893 QKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEI-DTIKNQN---QEKEKKCFEDLKI 948
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV----SQIASDFKISNQLSCELDDESEN 380
++EK E L ++Q +T + + + + + S + Q L+ E E+
Sbjct: 949 VKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 1008
Query: 381 TYERISLTL-DKITNHITYLNTQINETQKNDNAQLLWEAKK-QIADLTEQNIILKERLSQ 438
+ R++ + D+ + + ++ + D L + +++L + N IL ++L +
Sbjct: 1009 YHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFK 1068
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
E++ L IE R + E TL L+ + ++ + KV ++ +
Sbjct: 1069 TESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGK 1128
Query: 499 FEDLDDVMKQQQKE 512
E +++ + Q Q E
Sbjct: 1129 QESVEERLSQLQSE 1142
Score = 37.5 bits (83), Expect = 0.11
Identities = 45/214 (21%), Positives = 96/214 (44%), Gaps = 18/214 (8%)
Query: 178 TDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDL-------LKIENQ 230
++ N L+ E+ K+E +L ++L + + KQ+ + +++ L+ E Q
Sbjct: 1198 SECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQ 1257
Query: 231 NLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE----KLSEIKEKDENFKQEI 286
+L + + +++ K L ++ K++ K+ D+ + +
Sbjct: 1258 DLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQK 1317
Query: 287 DMLNEKLICDRRE-FNETMQEKNILLSDLSKKVNKT---ERELEEKQEQLTHLMEQLNDT 342
++LN L D +E + M+ K L +L +++ K ERE+ + L ++LN+
Sbjct: 1318 NLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEY 1377
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
EN + ++ K SQ D +I N+L ++DD
Sbjct: 1378 ENGEFSFHGDL--KTSQFEMDIQI-NKLKHKIDD 1408
Score = 36.3 bits (80), Expect = 0.26
Identities = 53/261 (20%), Positives = 106/261 (40%), Gaps = 16/261 (6%)
Query: 266 MLVEEKLSEIKEKDENFK-QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
+L+E+ E K+ K Q+ + E+L+ ++ E + K + + KVN +RE
Sbjct: 710 LLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVK---IKKMEDKVNVLQRE 766
Query: 325 LEEKQEQLTHLMEQLNDTENN--SYKLIENMFNKVSQIASDF--KISNQLSCELDD--ES 378
L E +E + L Q + E S + N + + A KI QL + + +
Sbjct: 767 LSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKE 826
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
+++ L+L + + + + +N+ + N +++Q A + + I+ Q
Sbjct: 827 VEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQ 886
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDS--STXXXXXXXXXXXXSNEIEDMKTKVME-- 494
E E + + + EE L+ K+S N+ ++ + K E
Sbjct: 887 KEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDL 946
Query: 495 --WKSQFEDLDDVMKQQQKEL 513
K + EDL +KQ ++ L
Sbjct: 947 KIVKEKNEDLQKTIKQNEETL 967
Score = 33.5 bits (73), Expect = 1.8
Identities = 59/321 (18%), Positives = 127/321 (39%), Gaps = 43/321 (13%)
Query: 150 EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLN 209
EI++ + + +N L KN E+ ++++K++ +K FE L
Sbjct: 888 EIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLK 947
Query: 210 NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
+K +Q+ + K + L Q + ++
Sbjct: 948 IVKEKNEDLQKTI---KQNEETLTQTISQYNGRLSVLTA---------------ENAMLN 989
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
KL K+ E + E++ + +L + +++ K +L + E Q
Sbjct: 990 SKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKR----ELELAFQRARDECSRLQ 1045
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+++ + L D N+ L + +F S++ N L E + E+ +L L
Sbjct: 1046 DKMNFDVSNLKD---NNEILSQQLFKTESKL-------NSLEIEFHHTRDALREK-TLGL 1094
Query: 390 DKITNHITYLNTQINE-TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETEN---KE 445
+++ ++ Q+ E QK N Q+ + K I ++++ +ERLSQL++EN ++
Sbjct: 1095 ERVQKDLSQTQCQMKEMEQKYQNEQV--KVNKYIG--KQESV--EERLSQLQSENMLLRQ 1148
Query: 446 LLIEIQTVRGSNEEVTLNLKD 466
L + + E+ +N++D
Sbjct: 1149 QLDDAHNKADNKEKTVINIQD 1169
Score = 31.5 bits (68), Expect = 7.4
Identities = 52/270 (19%), Positives = 105/270 (38%), Gaps = 15/270 (5%)
Query: 255 KFIANLEEMKTMLVE---EKLSE-IKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL 310
+F N EE K + EK+ E ++ K+E +++E+++ ++L + ++
Sbjct: 792 RFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEV-KQQLELSLQTLEMELRTVKSN 850
Query: 311 LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQL 370
L+ + ++ N +R+L +Q L + + + K IE K++ S+ S++
Sbjct: 851 LNQVVQERNDAQRQLSREQNARM-LQDGILTNHLSKQKEIEMAQKKMN---SENSHSHEE 906
Query: 371 SCELDDESENTYERIS---LTLDKITNHITYLNTQINETQK---NDNAQLLWEAKKQIAD 424
+L ++ E I+ L +D I N + E K N L K+
Sbjct: 907 EKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEET 966
Query: 425 LTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNE 484
LT+ RLS L EN L +++ + S E + ++ +
Sbjct: 967 LTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETS 1026
Query: 485 IEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++ + + L D M LK
Sbjct: 1027 KRELELAFQRARDECSRLQDKMNFDVSNLK 1056
>AL035416-6|CAI22779.1| 728|Homo sapiens hook homolog 1
(Drosophila) protein.
Length = 728
Score = 48.0 bits (109), Expect = 8e-05
Identities = 105/501 (20%), Positives = 198/501 (39%), Gaps = 48/501 (9%)
Query: 35 QLKSGLQQ-NVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHND 93
QLK L++ + +K + +E++ + L + EKL + +D
Sbjct: 179 QLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDD 238
Query: 94 ----LKKLYEDSASELEALKRENIQMHTS--DVMV-VPEIIDSLTEVINT---LTNGFES 143
+ K Y + +LE L+ EN ++ + D V E+ L E + LT+ E
Sbjct: 239 PNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEE 298
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
+ EID+ + + K N T+ ++ + D+N+LR +K L+ Y
Sbjct: 299 TRALKDEIDVLRATSDKANKLESTV--EIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVS 356
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNL-LQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
L E+L K N + +++ K + Q+L ++ +K A L+E
Sbjct: 357 LEEELK----KANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKE 412
Query: 263 MKTMLVEEK--LSEIKEKDENFKQEIDMLN---------------EKLICDRREFNETMQ 305
K L+E++ L E E+ + + D LN E + + RE +Q
Sbjct: 413 -KERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQ 471
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
+N +L L ++ ++ ER +EE QEQL ++N+ E +L + ++ Q D +
Sbjct: 472 HENKMLR-LQQEGSENER-IEELQEQLEQKHRKMNELETEQ-RLSKERIRELQQQIEDLQ 528
Query: 366 ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDN--AQLLWEAKKQIA 423
S Q E +SE E S K+ H+ L E QK L + + +
Sbjct: 529 KSLQ---EQGSKSEG--ESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQ 583
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
+ E L+++ ++ + + ++ R + + L +S
Sbjct: 584 KINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKER 643
Query: 484 EIE--DMKTKVMEWKSQFEDL 502
IE + + KV +++ E L
Sbjct: 644 RIEILESECKVAKFRDYEEKL 664
>AK128577-1|BAC87508.1| 1080|Homo sapiens protein ( Homo sapiens
cDNA FLJ46736 fis, clone TRACH3020769, weakly similar
to Myosin heavy chain, nonmuscle type B. ).
Length = 1080
Score = 48.0 bits (109), Expect = 8e-05
Identities = 73/374 (19%), Positives = 158/374 (42%), Gaps = 30/374 (8%)
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVD---KQNCIQEE 221
IK+ L+ + E ++ LR S+ E + +T EK+ EQL + K+ ++++
Sbjct: 330 IKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQ 389
Query: 222 VDL--------LKIENQNLLQXXXXXXXXXXXXXXXXXAR---DKFIAN-LEEMKTM-LV 268
++L L+ NL Q AR D + N L + K + +
Sbjct: 390 LELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMA 449
Query: 269 EEKL----SEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
++K+ S E++++ + ML E++ R E +T++ +N + KK + +
Sbjct: 450 QKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEI-DTIKNQN---QEKEKKCFEDLKI 505
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV----SQIASDFKISNQLSCELDDESEN 380
++EK E L ++Q +T + + + + + S + Q L+ E E+
Sbjct: 506 VKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 565
Query: 381 TYERISLTL-DKITNHITYLNTQINETQKNDNAQLLWEAKK-QIADLTEQNIILKERLSQ 438
+ R++ + D+ + + ++ + D L + +++L + N IL ++L +
Sbjct: 566 YHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFK 625
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
E++ L IE R + E TL L+ + ++ + KV ++ +
Sbjct: 626 TESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGK 685
Query: 499 FEDLDDVMKQQQKE 512
E +++ + Q Q E
Sbjct: 686 QESVEERLSQLQSE 699
Score = 37.1 bits (82), Expect = 0.15
Identities = 45/214 (21%), Positives = 96/214 (44%), Gaps = 18/214 (8%)
Query: 178 TDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDL-------LKIENQ 230
++ N L+ E+ K+E +L ++L + + KQ+ + +++ L+ E Q
Sbjct: 755 SECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQ 814
Query: 231 NLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE----KLSEIKEKDENFKQEI 286
+L + + +++ K L ++ K++ K+ D+ + +
Sbjct: 815 DLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTIKKQMDKIEELQK 874
Query: 287 DMLNEKLICDRRE-FNETMQEKNILLSDLSKKVNKT---ERELEEKQEQLTHLMEQLNDT 342
++LN L D +E + M+ K L +L +++ K ERE+ + L ++LN+
Sbjct: 875 NLLNANLSEDEKEQLKKLMELKQSLECNLGQEMKKNVELEREITGFKNLLKMTRKKLNEY 934
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
EN + ++ K SQ D +I N+L ++DD
Sbjct: 935 ENGEFSFHGDL--KTSQFEMDIQI-NKLKHKIDD 965
Score = 36.3 bits (80), Expect = 0.26
Identities = 53/261 (20%), Positives = 106/261 (40%), Gaps = 16/261 (6%)
Query: 266 MLVEEKLSEIKEKDENFK-QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
+L+E+ E K+ K Q+ + E+L+ ++ E + K + + KVN +RE
Sbjct: 267 LLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVK---IKKMEDKVNVLQRE 323
Query: 325 LEEKQEQLTHLMEQLNDTENN--SYKLIENMFNKVSQIASDF--KISNQLSCELDD--ES 378
L E +E + L Q + E S + N + + A KI QL + + +
Sbjct: 324 LSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKE 383
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
+++ L+L + + + + +N+ + N +++Q A + + I+ Q
Sbjct: 384 VEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQ 443
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDS--STXXXXXXXXXXXXSNEIEDMKTKVME-- 494
E E + + + EE L+ K+S N+ ++ + K E
Sbjct: 444 KEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDL 503
Query: 495 --WKSQFEDLDDVMKQQQKEL 513
K + EDL +KQ ++ L
Sbjct: 504 KIVKEKNEDLQKTIKQNEETL 524
Score = 33.5 bits (73), Expect = 1.8
Identities = 59/321 (18%), Positives = 127/321 (39%), Gaps = 43/321 (13%)
Query: 150 EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLN 209
EI++ + + +N L KN E+ ++++K++ +K FE L
Sbjct: 445 EIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLK 504
Query: 210 NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
+K +Q+ + K + L Q + ++
Sbjct: 505 IVKEKNEDLQKTI---KQNEETLTQTISQYNGRLSVLTA---------------ENAMLN 546
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
KL K+ E + E++ + +L + +++ K +L + E Q
Sbjct: 547 SKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKR----ELELAFQRARDECSRLQ 602
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+++ + L D N+ L + +F S++ N L E + E+ +L L
Sbjct: 603 DKMNFDVSNLKD---NNEILSQQLFKTESKL-------NSLEIEFHHTRDALREK-TLGL 651
Query: 390 DKITNHITYLNTQINE-TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETEN---KE 445
+++ ++ Q+ E QK N Q+ + K I ++++ +ERLSQL++EN ++
Sbjct: 652 ERVQKDLSQTQCQMKEMEQKYQNEQV--KVNKYIG--KQESV--EERLSQLQSENMLLRQ 705
Query: 446 LLIEIQTVRGSNEEVTLNLKD 466
L + + E+ +N++D
Sbjct: 706 QLDDAHNKADNKEKTVINIQD 726
Score = 31.5 bits (68), Expect = 7.4
Identities = 52/270 (19%), Positives = 105/270 (38%), Gaps = 15/270 (5%)
Query: 255 KFIANLEEMKTMLVE---EKLSE-IKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL 310
+F N EE K + EK+ E ++ K+E +++E+++ ++L + ++
Sbjct: 349 RFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEV-KQQLELSLQTLEMELRTVKSN 407
Query: 311 LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQL 370
L+ + ++ N +R+L +Q L + + + K IE K++ S+ S++
Sbjct: 408 LNQVVQERNDAQRQLSREQNARM-LQDGILTNHLSKQKEIEMAQKKMN---SENSHSHEE 463
Query: 371 SCELDDESENTYERIS---LTLDKITNHITYLNTQINETQK---NDNAQLLWEAKKQIAD 424
+L ++ E I+ L +D I N + E K N L K+
Sbjct: 464 EKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEET 523
Query: 425 LTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNE 484
LT+ RLS L EN L +++ + S E + ++ +
Sbjct: 524 LTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETS 583
Query: 485 IEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++ + + L D M LK
Sbjct: 584 KRELELAFQRARDECSRLQDKMNFDVSNLK 613
>AF044923-1|AAC09298.1| 728|Homo sapiens hook1 protein protein.
Length = 728
Score = 48.0 bits (109), Expect = 8e-05
Identities = 105/501 (20%), Positives = 198/501 (39%), Gaps = 48/501 (9%)
Query: 35 QLKSGLQQ-NVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHND 93
QLK L++ + +K + +E++ + L + EKL + +D
Sbjct: 179 QLKRALEELQEALAEKEELRQRCEELDMQVTTLQDEKNSLVSENEMMNEKLDQLDGSFDD 238
Query: 94 ----LKKLYEDSASELEALKRENIQMHTS--DVMV-VPEIIDSLTEVINT---LTNGFES 143
+ K Y + +LE L+ EN ++ + D V E+ L E + LT+ E
Sbjct: 239 PNTVVAKKYFHAQLQLEQLQEENFRLEAAKDDYRVHCEELEKQLIEFQHRNDELTSLAEE 298
Query: 144 LEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEK 203
+ EID+ + + K N T+ ++ + D+N+LR +K L+ Y
Sbjct: 299 TRALKDEIDVLRATSDKANKLESTV--EIYRQKLQDLNDLRKQVKTLQETNMMYMHNTVS 356
Query: 204 LFEQLNNAVDKQNCIQEEVDLLKIENQNL-LQXXXXXXXXXXXXXXXXXARDKFIANLEE 262
L E+L K N + +++ K + Q+L ++ +K A L+E
Sbjct: 357 LEEELK----KANAARTQLETYKRQVQDLHVKLSSESKRADTLAFEMKRLEEKHEALLKE 412
Query: 263 MKTMLVEEK--LSEIKEKDENFKQEIDMLN---------------EKLICDRREFNETMQ 305
K L+E++ L E E+ + + D LN E + + RE +Q
Sbjct: 413 -KERLIEQRDTLKETNEELRCSQVQQDHLNQTDASATKSYENLAAEIMPVEYREVFIRLQ 471
Query: 306 EKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFK 365
+N +L L ++ ++ ER +EE QEQL ++N+ E +L + ++ Q D +
Sbjct: 472 HENKMLR-LQQEGSENER-IEELQEQLEQKHRKMNELETEQ-RLSKERIRELQQQIEDLQ 528
Query: 366 ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDN--AQLLWEAKKQIA 423
S Q E +SE E S K+ H+ L E QK L + + +
Sbjct: 529 KSLQ---EQGSKSEG--ESSSKLKQKLEAHMEKLTEVHEELQKKQELIEDLQPDINQNVQ 583
Query: 424 DLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSN 483
+ E L+++ ++ + + ++ R + + L +S
Sbjct: 584 KINELEAALQKKDEDMKAMEERYKMYLEKARNVIKTLDPKLNPASAEIMLLRKQLAEKER 643
Query: 484 EIE--DMKTKVMEWKSQFEDL 502
IE + + KV +++ E L
Sbjct: 644 RIEILESECKVAKFRDYEEKL 664
>AB210007-1|BAE06089.1| 2121|Homo sapiens NUMA1 variant protein
protein.
Length = 2121
Score = 48.0 bits (109), Expect = 8e-05
Identities = 61/376 (16%), Positives = 151/376 (40%), Gaps = 13/376 (3%)
Query: 128 DSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSI 187
+SLT ++ + L+ ++D K N ++++N + L + + + + L
Sbjct: 292 ESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQLQDALNELT 351
Query: 188 KYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXX 247
+ E+ +L ++L+ A+ + C++E+ ++L+ + L +
Sbjct: 352 EEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQLQDNPPQEK 411
Query: 248 XXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEK 307
+ L++ L ++++ + E + E KL+ +R F E Q+
Sbjct: 412 GEVLGDVLQLETLKQEAATLAANN-TQLQARVEMLETERGQQEAKLLAERGHFEEEKQQL 470
Query: 308 NILLSDLSKKV---NKTERELEEKQE----QLTHLMEQLNDTENNSYKLIENMFNKVSQI 360
+ L++DL + ++ + ELE+ + +LT + L I+ +++ +
Sbjct: 471 SSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNATIQQQDQELAGL 530
Query: 361 ASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKK 420
K + + E + + ++++++ + Q+ E + A A++
Sbjct: 531 KQQAKEKQAQLAQTLQQQEQASQGLRHQVEQLSSSLKQKEQQLKEVAEKQEATRQDHAQQ 590
Query: 421 QIADLTEQNIILKER---LSQLETENKELLIEIQTVRGSNEEVTLNLKDSS-TXXXXXXX 476
E+ L+ER L QLE KE +++ ++ +V +DS+ T
Sbjct: 591 LATAAEEREASLRERDAALKQLEALEKEKAAKLEILQ-QQLQVANEARDSAQTSVTQAQR 649
Query: 477 XXXXXSNEIEDMKTKV 492
S ++E+++ V
Sbjct: 650 EKAELSRKVEELQACV 665
Score = 45.2 bits (102), Expect = 6e-04
Identities = 91/509 (17%), Positives = 198/509 (38%), Gaps = 49/509 (9%)
Query: 36 LKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTI--AETKHND 93
L S L++ V + ++ V E + + ++L L E+L + AET N
Sbjct: 1232 LISSLEEEVSILNRQVLEKEGES-----KELKRLVMAESEKSQKLEERLRLLQAETASNS 1286
Query: 94 LKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDL 153
+ A+E + RE +Q + ++L + LT+ E EE+ E+
Sbjct: 1287 AR------AAERSSALREEVQSLREEAEKQRVASENLRQ---ELTSQAERAEELGQELKA 1337
Query: 154 KKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVD 213
+ + ++ TL + T + ++EL + + +++E A ++ E+L +
Sbjct: 1338 WQEKFFQKEQALSTLQLEH-TSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQ 1396
Query: 214 KQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKT---MLVEE 270
++ E+ + E L+ + + L +K +L EE
Sbjct: 1397 AAGGLRAELLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEE 1456
Query: 271 K--LSEIKEKDENFKQ-EIDMLNEKLICD---------------RREFNETMQEKNILLS 312
L E F + E+D EK + + +RE T +E ++ +
Sbjct: 1457 NRGLGERANLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTA 1516
Query: 313 DLSK---KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
KV + + +E++++LT +EQL + K +E + K++ K+ Q
Sbjct: 1517 KYEGAKVKVLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQ 1576
Query: 370 LSCELD---DESENTYERISLTLDKITNHITYLNTQINETQ-KNDNAQLLWEAKKQIADL 425
+ ES+ +R+ L+++ ++ + + + A+ ++AKKQ
Sbjct: 1577 KLKAVQAQGGESQQEAQRLQAQLNELQAQLSQKEQAAEHYKLQMEKAKTHYDAKKQQNQE 1636
Query: 426 TEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEI 485
++ + L QL+ ENKEL E + + ++ L K++ ++
Sbjct: 1637 LQEQL---RSLEQLQKENKELRAEAERLGHELQQAGLKTKEAEQTCRHLTAQVRSLEAQV 1693
Query: 486 EDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
++ + +F+ D +K ++ + K
Sbjct: 1694 AHADQQLRD-LGKFQVATDALKSREPQAK 1721
Score = 41.5 bits (93), Expect = 0.007
Identities = 61/354 (17%), Positives = 146/354 (41%), Gaps = 19/354 (5%)
Query: 169 LDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIE 228
L++L KNE+ L ++K + +K+E + + K+ + D ++E L+
Sbjct: 284 LEELRDKNESLTMRLHETLKQCQDLKTEKSQMDRKINQLSEENGDLSFKLREFASHLQQL 343
Query: 229 NQNLLQXXXXXXXXXXXXXXXXXARDKFI-ANLEEMKTM-----LVEEKLSEIKEKDENF 282
L + +K + A L++ K + +++ KLS+++E
Sbjct: 344 QDALNELTEEHSKATQEWLEKQAQLEKELSAALQDKKCLEEKNEILQGKLSQLEEHLSQL 403
Query: 283 KQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDT 342
+ +++ D + QE L ++ ++ + E E+ +Q L+ +
Sbjct: 404 QDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQLQARVEMLETERGQQEAKLLAERGHF 463
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQ 402
E + + + ++ + S +Q EL+ S+ R++ + +T+ +T LN
Sbjct: 464 EEEK----QQLSSLITDLQSSISNLSQAKEELEQASQAHGARLTAQVASLTSELTTLNAT 519
Query: 403 INETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTL 462
I + Q + A L +AK++ A L + L Q E ++ L +++ + S ++
Sbjct: 520 IQQ-QDQELAGLKQQAKEKQAQLA-------QTLQQQEQASQGLRHQVEQLSSSLKQKEQ 571
Query: 463 NLKD-SSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQKELKL 515
LK+ + + E+ + + E + + L+ + K++ +L++
Sbjct: 572 QLKEVAEKQEATRQDHAQQLATAAEEREASLRERDAALKQLEALEKEKAAKLEI 625
>AB053468-1|BAC54107.1| 992|Homo sapiens ELKS beta protein.
Length = 992
Score = 48.0 bits (109), Expect = 8e-05
Identities = 97/474 (20%), Positives = 198/474 (41%), Gaps = 39/474 (8%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
+TV E+K+ +I+SM R L + E + ++K++ E S + +
Sbjct: 381 QTVIEMKDSKISSMERGLRDLEEEIQMLK---SNGALSTEEREEEMKQM-EVYRSHSKFM 436
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSIT-KDNIS--I 165
K + Q+ E++ +L + TLTN F ++ I++ K S+T K+ + +
Sbjct: 437 KNKIGQVKQELSRKDTELL-ALQTKLETLTNQFSDSKQ---HIEVLKESLTAKEQRAAIL 492
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLL 225
+T +D L + E L K ++ + E T ++ + L + +D + + +V++L
Sbjct: 493 QTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHD-LKDMLDVK---ERKVNVL 548
Query: 226 KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQE 285
+ + +NL + + N + T L EE L+E + E K++
Sbjct: 549 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL-EEALAEKERTIERLKEQ 607
Query: 286 IDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN 345
D D RE E + L DL +KV+ + +L EK+ L L E + ++
Sbjct: 608 RDR-------DEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS 660
Query: 346 SYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
K + K +IA + K L E + + + ++++ I +L +I
Sbjct: 661 GLKKDSRL--KTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI-- 716
Query: 406 TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL----IEIQTVRGSNEEVT 461
T+ D + +A+ ++ L E ILKE ++ ++K++ + + V+ N++V
Sbjct: 717 TRYKDESS---KAQAEVDRLLE---ILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVA 770
Query: 462 LNLKDSSTXXXXXXXXXXXXSNEIED-MKTKVMEWKSQFEDLDDVMKQQQKELK 514
NLK + ED + + + DD +++ ++ L+
Sbjct: 771 -NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALR 823
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/289 (18%), Positives = 108/289 (37%), Gaps = 7/289 (2%)
Query: 100 DSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEID-LKKNSI 158
+ + ++ L+RE I + + +D L E++ + N ++ E++ L +
Sbjct: 704 EMSDRIQHLERE-ITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQV 762
Query: 159 TKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCI 218
N + L K + + L + + +++ + L ++ + + + +
Sbjct: 763 KDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEAL 822
Query: 219 QEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML--VEEKLSEIK 276
+E V + L Q A +K LE MK L ++ L+E +
Sbjct: 823 RESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE 882
Query: 277 EKDENFKQEIDM-LNEKLICDRREFNETMQEK--NILLSDLSKKVNKTERELEEKQEQLT 333
N + E L E L + + EK NI L +LS KT+ E+ + +
Sbjct: 883 THLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKD 942
Query: 334 HLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
L++QL N KL+ + + +S +N DE E +
Sbjct: 943 RLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQDEEEGIW 991
Score = 44.0 bits (99), Expect = 0.001
Identities = 66/358 (18%), Positives = 141/358 (39%), Gaps = 17/358 (4%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++LEE+ L I+ +K ++ + SIK LL+ L +K + + + ++E + +
Sbjct: 286 KTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHH 345
Query: 202 -EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L EQ +K+N + E + EN + ++ + +L
Sbjct: 346 LESLLEQ----KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDL 401
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDR-REFNETMQEKNILLSDLSKKV 318
EE ML +E++E KQ E+ + K + ++ + + + K+ L L K+
Sbjct: 402 EEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKL 461
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ + ++ + L E L E + L + ++ + N+ + ++ D +
Sbjct: 462 ETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA 521
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
E + + + + + ++N QK + ++Q+ D +Q LKER+
Sbjct: 522 EEKGTQAG-EIHDLKDMLDVKERKVNVLQKK-----IENLQEQLRDKEKQMSSLKERVKS 575
Query: 439 LE---TENKELLIEIQTVRGSNEEVTLNLKDS-STXXXXXXXXXXXXSNEIEDMKTKV 492
L+ T L ++ E LK+ +++D+K KV
Sbjct: 576 LQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKV 633
Score = 33.9 bits (74), Expect = 1.4
Identities = 53/209 (25%), Positives = 88/209 (42%), Gaps = 16/209 (7%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTE-KLTIAET 89
K+I +L+S + V +K VA LK+ E Q+ E L +
Sbjct: 749 KKIAELESLTSRQVKDQNKKVANLKHKE------QVEKKKSAQMLEEARRREDNLNDSSQ 802
Query: 90 KHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVAL 149
+ D + +D ELE RE++Q+ MV+ + + T + ++E+V
Sbjct: 803 QLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQ 862
Query: 150 EIDLKKNSITKDNISI---KTLLDKLITKNETDINE-LRNSIKYLESVKSEYNTANEKLF 205
E++ K ++ S+ +T L L + + E L + L + SE AN L
Sbjct: 863 ELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISE-KDANIALL 921
Query: 206 EQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
E L+++ K QEEV LK E L+Q
Sbjct: 922 E-LSSSKKK---TQEEVAALKREKDRLVQ 946
>AB029004-1|BAA83033.2| 1003|Homo sapiens KIAA1081 protein protein.
Length = 1003
Score = 48.0 bits (109), Expect = 8e-05
Identities = 97/474 (20%), Positives = 198/474 (41%), Gaps = 39/474 (8%)
Query: 49 KTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEAL 108
+TV E+K+ +I+SM R L + E + ++K++ E S + +
Sbjct: 392 QTVIEMKDSKISSMERGLRDLEEEIQMLK---SNGALSTEEREEEMKQM-EVYRSHSKFM 447
Query: 109 KRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSIT-KDNIS--I 165
K + Q+ E++ +L + TLTN F ++ I++ K S+T K+ + +
Sbjct: 448 KNKIGQVKQELSRKDTELL-ALQTKLETLTNQFSDSKQ---HIEVLKESLTAKEQRAAIL 503
Query: 166 KTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLL 225
+T +D L + E L K ++ + E T ++ + L + +D + + +V++L
Sbjct: 504 QTEVDALRLRLEEKETMLNKKTKQIQDMAEEKGTQAGEIHD-LKDMLDVK---ERKVNVL 559
Query: 226 KIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQE 285
+ + +NL + + N + T L EE L+E + E K++
Sbjct: 560 QKKIENLQEQLRDKEKQMSSLKERVKSLQADTTNTDTALTTL-EEALAEKERTIERLKEQ 618
Query: 286 IDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN 345
D D RE E + L DL +KV+ + +L EK+ L L E + ++
Sbjct: 619 RDR-------DEREKQEEIDNYKKDLKDLKEKVSLLQGDLSEKEASLLDLKEHASSLASS 671
Query: 346 SYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINE 405
K + K +IA + K L E + + + ++++ I +L +I
Sbjct: 672 GLKKDSRL--KTLEIALEQKKEECLKMESQLKKAHEAALEARASPEMSDRIQHLEREI-- 727
Query: 406 TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELL----IEIQTVRGSNEEVT 461
T+ D + +A+ ++ L E ILKE ++ ++K++ + + V+ N++V
Sbjct: 728 TRYKDESS---KAQAEVDRLLE---ILKEVENEKNDKDKKIAELESLTSRQVKDQNKKVA 781
Query: 462 LNLKDSSTXXXXXXXXXXXXSNEIED-MKTKVMEWKSQFEDLDDVMKQQQKELK 514
NLK + ED + + + DD +++ ++ L+
Sbjct: 782 -NLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEALR 834
Score = 46.8 bits (106), Expect = 2e-04
Identities = 54/289 (18%), Positives = 108/289 (37%), Gaps = 7/289 (2%)
Query: 100 DSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEID-LKKNSI 158
+ + ++ L+RE I + + +D L E++ + N ++ E++ L +
Sbjct: 715 EMSDRIQHLERE-ITRYKDESSKAQAEVDRLLEILKEVENEKNDKDKKIAELESLTSRQV 773
Query: 159 TKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCI 218
N + L K + + L + + +++ + L ++ + + + +
Sbjct: 774 KDQNKKVANLKHKEQVEKKKSAQMLEEARRREDNLNDSSQQLQDSLRKKDDRIEELEEAL 833
Query: 219 QEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTML--VEEKLSEIK 276
+E V + L Q A +K LE MK L ++ L+E +
Sbjct: 834 RESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQELESMKAKLSSTQQSLAEKE 893
Query: 277 EKDENFKQEIDM-LNEKLICDRREFNETMQEK--NILLSDLSKKVNKTERELEEKQEQLT 333
N + E L E L + + EK NI L +LS KT+ E+ + +
Sbjct: 894 THLTNLRAERRKHLEEVLEMKQEALLAAISEKDANIALLELSSSKKKTQEEVAALKREKD 953
Query: 334 HLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTY 382
L++QL N KL+ + + +S +N DE E +
Sbjct: 954 RLVQQLKQQTQNRMKLMADNYEDDHFKSSHSNQTNHKPSPDQDEEEGIW 1002
Score = 44.0 bits (99), Expect = 0.001
Identities = 66/358 (18%), Positives = 141/358 (39%), Gaps = 17/358 (4%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
++LEE+ L I+ +K ++ + SIK LL+ L +K + + + ++E + +
Sbjct: 297 KTLEEMELRIETQKQTLNARDESIKKLLEMLQSKGLSAKATEEDHERTRRLAEAEMHVHH 356
Query: 202 -EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANL 260
E L EQ +K+N + E + EN + ++ + +L
Sbjct: 357 LESLLEQ----KEKENSMLREEMHRRFENAPDSAKTKALQTVIEMKDSKISSMERGLRDL 412
Query: 261 EEMKTMLVEEKLSEIKEKDENFKQ-EIDMLNEKLICDR-REFNETMQEKNILLSDLSKKV 318
EE ML +E++E KQ E+ + K + ++ + + + K+ L L K+
Sbjct: 413 EEEIQMLKSNGALSTEEREEEMKQMEVYRSHSKFMKNKIGQVKQELSRKDTELLALQTKL 472
Query: 319 NKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDES 378
+ + ++ + L E L E + L + ++ + N+ + ++ D +
Sbjct: 473 ETLTNQFSDSKQHIEVLKESLTAKEQRAAILQTEVDALRLRLEEKETMLNKKTKQIQDMA 532
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
E + + + + + ++N QK + ++Q+ D +Q LKER+
Sbjct: 533 EEKGTQAG-EIHDLKDMLDVKERKVNVLQKK-----IENLQEQLRDKEKQMSSLKERVKS 586
Query: 439 LE---TENKELLIEIQTVRGSNEEVTLNLKDS-STXXXXXXXXXXXXSNEIEDMKTKV 492
L+ T L ++ E LK+ +++D+K KV
Sbjct: 587 LQADTTNTDTALTTLEEALAEKERTIERLKEQRDRDEREKQEEIDNYKKDLKDLKEKV 644
Score = 33.9 bits (74), Expect = 1.4
Identities = 53/209 (25%), Positives = 88/209 (42%), Gaps = 16/209 (7%)
Query: 31 KEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTE-KLTIAET 89
K+I +L+S + V +K VA LK+ E Q+ E L +
Sbjct: 760 KKIAELESLTSRQVKDQNKKVANLKHKE------QVEKKKSAQMLEEARRREDNLNDSSQ 813
Query: 90 KHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVAL 149
+ D + +D ELE RE++Q+ MV+ + + T + ++E+V
Sbjct: 814 QLQDSLRKKDDRIEELEEALRESVQITAEREMVLAQEESARTNAEKQVEELLMAMEKVKQ 873
Query: 150 EIDLKKNSITKDNISI---KTLLDKLITKNETDINE-LRNSIKYLESVKSEYNTANEKLF 205
E++ K ++ S+ +T L L + + E L + L + SE AN L
Sbjct: 874 ELESMKAKLSSTQQSLAEKETHLTNLRAERRKHLEEVLEMKQEALLAAISE-KDANIALL 932
Query: 206 EQLNNAVDKQNCIQEEVDLLKIENQNLLQ 234
E L+++ K QEEV LK E L+Q
Sbjct: 933 E-LSSSKKK---TQEEVAALKREKDRLVQ 957
>AB028997-1|BAA83026.2| 1715|Homo sapiens KIAA1074 protein protein.
Length = 1715
Score = 48.0 bits (109), Expect = 8e-05
Identities = 73/374 (19%), Positives = 158/374 (42%), Gaps = 30/374 (8%)
Query: 165 IKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVD---KQNCIQEE 221
IK+ L+ + E ++ LR S+ E + +T EK+ EQL + K+ ++++
Sbjct: 778 IKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEVKQQ 837
Query: 222 VDL--------LKIENQNLLQXXXXXXXXXXXXXXXXXAR---DKFIAN-LEEMKTM-LV 268
++L L+ NL Q AR D + N L + K + +
Sbjct: 838 LELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQKEIEMA 897
Query: 269 EEKL----SEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
++K+ S E++++ + ML E++ R E +T++ +N + KK + +
Sbjct: 898 QKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEI-DTIKNQN---QEKEKKCFEDLKI 953
Query: 325 LEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV----SQIASDFKISNQLSCELDDESEN 380
++EK E L ++Q +T + + + + + S + Q L+ E E+
Sbjct: 954 VKEKNEDLQKTIKQNEETLTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVES 1013
Query: 381 TYERISLTL-DKITNHITYLNTQINETQKNDNAQLLWEAKK-QIADLTEQNIILKERLSQ 438
+ R++ + D+ + + ++ + D L + +++L + N IL ++L +
Sbjct: 1014 YHSRLAAAIHDRDQSETSKRELELAFQRARDECSRLQDKMNFDVSNLKDNNEILSQQLFK 1073
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQ 498
E++ L IE R + E TL L+ + ++ + KV ++ +
Sbjct: 1074 TESKLNSLEIEFHHTRDALREKTLGLERVQKDLSQTQCQMKEMEQKYQNEQVKVNKYIGK 1133
Query: 499 FEDLDDVMKQQQKE 512
E +++ + Q Q E
Sbjct: 1134 QESVEERLSQLQSE 1147
Score = 37.5 bits (83), Expect = 0.11
Identities = 45/214 (21%), Positives = 96/214 (44%), Gaps = 18/214 (8%)
Query: 178 TDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDL-------LKIENQ 230
++ N L+ E+ K+E +L ++L + + KQ+ + +++ L+ E Q
Sbjct: 1203 SECNHLKERQYQYENEKAEREVVVRQLQQELADTLKKQSMSEASLEVTSRYRINLEDETQ 1262
Query: 231 NLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEE----KLSEIKEKDENFKQEI 286
+L + + +++ K L ++ K++ K+ D+ + +
Sbjct: 1263 DLKKKLGQIRNQLQEAQDRHTEAVRCAEKMQDHKQKLEKDNAKLKVTVKKQMDKIEELQK 1322
Query: 287 DMLNEKLICDRRE-FNETMQEKNILLSDLSKKVNKT---ERELEEKQEQLTHLMEQLNDT 342
++LN L D +E + M+ K L +L +++ K ERE+ + L ++LN+
Sbjct: 1323 NLLNANLSEDEKEQLKKLMELKQSLECNLDQEMKKNVELEREITGFKNLLKMTRKKLNEY 1382
Query: 343 ENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
EN + ++ K SQ D +I N+L ++DD
Sbjct: 1383 ENGEFSFHGDL--KTSQFEMDIQI-NKLKHKIDD 1413
Score = 36.3 bits (80), Expect = 0.26
Identities = 53/261 (20%), Positives = 106/261 (40%), Gaps = 16/261 (6%)
Query: 266 MLVEEKLSEIKEKDENFK-QEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERE 324
+L+E+ E K+ K Q+ + E+L+ ++ E + K + + KVN +RE
Sbjct: 715 LLIEQLGMECKDSVSLLKIQDAALSCERLLELKKNHCELLTVK---IKKMEDKVNVLQRE 771
Query: 325 LEEKQEQLTHLMEQLNDTENN--SYKLIENMFNKVSQIASDF--KISNQLSCELDD--ES 378
L E +E + L Q + E S + N + + A KI QL + + +
Sbjct: 772 LSETKEIKSQLEHQKVEWERELCSLRFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKE 831
Query: 379 ENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQ 438
+++ L+L + + + + +N+ + N +++Q A + + I+ Q
Sbjct: 832 VEVKQQLELSLQTLEMELRTVKSNLNQVVQERNDAQRQLSREQNARMLQDGILTNHLSKQ 891
Query: 439 LETENKELLIEIQTVRGSNEEVTLNLKDS--STXXXXXXXXXXXXSNEIEDMKTKVME-- 494
E E + + + EE L+ K+S N+ ++ + K E
Sbjct: 892 KEIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDL 951
Query: 495 --WKSQFEDLDDVMKQQQKEL 513
K + EDL +KQ ++ L
Sbjct: 952 KIVKEKNEDLQKTIKQNEETL 972
Score = 33.5 bits (73), Expect = 1.8
Identities = 59/321 (18%), Positives = 127/321 (39%), Gaps = 43/321 (13%)
Query: 150 EIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLN 209
EI++ + + +N L KN E+ ++++K++ +K FE L
Sbjct: 893 EIEMAQKKMNSENSHSHEEEKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLK 952
Query: 210 NAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVE 269
+K +Q+ + K + L Q + ++
Sbjct: 953 IVKEKNEDLQKTI---KQNEETLTQTISQYNGRLSVLTA---------------ENAMLN 994
Query: 270 EKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQ 329
KL K+ E + E++ + +L + +++ K +L + E Q
Sbjct: 995 SKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETSKR----ELELAFQRARDECSRLQ 1050
Query: 330 EQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+++ + L D N+ L + +F S++ N L E + E+ +L L
Sbjct: 1051 DKMNFDVSNLKD---NNEILSQQLFKTESKL-------NSLEIEFHHTRDALREK-TLGL 1099
Query: 390 DKITNHITYLNTQINE-TQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETEN---KE 445
+++ ++ Q+ E QK N Q+ + K I ++++ +ERLSQL++EN ++
Sbjct: 1100 ERVQKDLSQTQCQMKEMEQKYQNEQV--KVNKYIG--KQESV--EERLSQLQSENMLLRQ 1153
Query: 446 LLIEIQTVRGSNEEVTLNLKD 466
L + + E+ +N++D
Sbjct: 1154 QLDDAHNKADNKEKTVINIQD 1174
Score = 31.5 bits (68), Expect = 7.4
Identities = 52/270 (19%), Positives = 105/270 (38%), Gaps = 15/270 (5%)
Query: 255 KFIANLEEMKTMLVE---EKLSE-IKEKDENFKQEIDMLNEKLICDRREFNETMQEKNIL 310
+F N EE K + EK+ E ++ K+E +++E+++ ++L + ++
Sbjct: 797 RFSLNQEEEKRRNADTLYEKIREQLRRKEEQYRKEVEV-KQQLELSLQTLEMELRTVKSN 855
Query: 311 LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQL 370
L+ + ++ N +R+L +Q L + + + K IE K++ S+ S++
Sbjct: 856 LNQVVQERNDAQRQLSREQNARM-LQDGILTNHLSKQKEIEMAQKKMN---SENSHSHEE 911
Query: 371 SCELDDESENTYERIS---LTLDKITNHITYLNTQINETQK---NDNAQLLWEAKKQIAD 424
+L ++ E I+ L +D I N + E K N L K+
Sbjct: 912 EKDLSHKNSMLQEEIAMLRLEIDTIKNQNQEKEKKCFEDLKIVKEKNEDLQKTIKQNEET 971
Query: 425 LTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNE 484
LT+ RLS L EN L +++ + S E + ++ +
Sbjct: 972 LTQTISQYNGRLSVLTAENAMLNSKLENEKQSKERLEAEVESYHSRLAAAIHDRDQSETS 1031
Query: 485 IEDMKTKVMEWKSQFEDLDDVMKQQQKELK 514
+++ + + L D M LK
Sbjct: 1032 KRELELAFQRARDECSRLQDKMNFDVSNLK 1061
>U43195-1|AAB02814.1| 1354|Homo sapiens Rho-associated, coiled-coil
containing protein kinase p160ROCK protein.
Length = 1354
Score = 47.6 bits (108), Expect = 1e-04
Identities = 92/405 (22%), Positives = 172/405 (42%), Gaps = 41/405 (10%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMV-VPEIIDSLTEVINTLT 138
L E+ I E + K Y + LEA +R+ + H S+++ + I SL E + L
Sbjct: 585 LQERNRILENSKSQTDKDYYQLQAILEAERRD--RGHDSEMIGDLQARITSLQEEVKHLK 642
Query: 139 NGFESLEEVALEI-------DLKKNSITKD-NISIKTLLDKLITK-NETDINELRNSIKY 189
+ E +E E + +KN++ D N +K+L +L + NE + + R + K+
Sbjct: 643 HNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKH 702
Query: 190 --LESVKSEYNTANEKLFEQLNNAVDK-QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
+E KS EK ++ A +K +N + + + + +L Q
Sbjct: 703 QSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNK 762
Query: 247 XXXXXARDKFIANLEEM--KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
LE+ K +L++ +L + +N K L +++ ++E N +
Sbjct: 763 ERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKG----LEKQM---KQEINTLL 815
Query: 305 QEKNIL---LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
+ K +L L+ L+K+ E ++ E Q+QL EQ T YK +V ++
Sbjct: 816 EAKRLLEFELAQLTKQYRGNEGQMRELQDQLE--AEQYFST---LYK------TQVKELK 864
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQ 421
+ + N+ + + E +N E ++ LD + Q+ + L + K+
Sbjct: 865 EEIEEKNRENLKKIQELQNEKETLATQLDLAETKAE--SEQLARGLLEEQYFELTQESKK 922
Query: 422 IADLTEQNIILKER-LSQLETENKELLIEIQTVRGSNEEVTLNLK 465
A Q I K+ +S+LE N L +I+ +R NEE+T +K
Sbjct: 923 AASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMK 967
Score = 39.5 bits (88), Expect = 0.028
Identities = 91/467 (19%), Positives = 199/467 (42%), Gaps = 48/467 (10%)
Query: 24 IRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLT 81
I+L++ KE+ + + ++N+ + TV++++ ++ + I + +
Sbjct: 458 IKLDKIMKELDE-EGNQRRNL---ESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVE 513
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPE------IIDSLTEVIN 135
+++ + + DLKK+ ++S E L + Q+ ++ ++ E + S TE+
Sbjct: 514 NEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSK 573
Query: 136 TLTNGFESLEEVALE----IDLKKNSITKDNISIKTLLDKLITKNETD---INELRNSIK 188
+++ ESL E ++ K+ KD ++ +L+ D I +L+ I
Sbjct: 574 SISQ-LESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARIT 632
Query: 189 YLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXX 248
L+ EK+ + A D N ++E + L+I+ L+
Sbjct: 633 SLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHK 692
Query: 249 XXXAR--DKFIANLEEMKTMLV---EEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
AR DK ++EE K++ + E+KL E +E E + + + ++ C + +
Sbjct: 693 VTKARLTDKH-QSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQ--CSMLDVDLK 749
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
++ + + + + +E++ + LT +EQ E+N L++N + A +
Sbjct: 750 QSQQKL------EHLTGNKERMEDEVKNLTLQLEQ----ESNKRLLLQNELKTQAFEADN 799
Query: 364 FK-ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
K + Q+ E++ E + L ++T Q+ E Q QL EA++
Sbjct: 800 LKGLEKQMKQEINTLLE-AKRLLEFELAQLTKQYRGNEGQMRELQD----QL--EAEQYF 852
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSST 469
+ L + + KE ++E +N+E L +IQ ++ E + L + T
Sbjct: 853 STLYKTQV--KELKEEIEEKNRENLKKIQELQNEKETLATQLDLAET 897
Score = 32.7 bits (71), Expect = 3.2
Identities = 54/211 (25%), Positives = 86/211 (40%), Gaps = 23/211 (10%)
Query: 174 TKNETDINELRNSI--KYLESVKSEYNTANEK--LFEQLNNAVDKQNCIQEEVDLLKIEN 229
T +T + EL+ I K E++K NEK L QL+ A K Q LL+ +
Sbjct: 854 TLYKTQVKELKEEIEEKNRENLKKIQELQNEKETLATQLDLAETKAESEQLARGLLEEQY 913
Query: 230 QNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDML 289
L Q +D ++ LEE +ML ++ E ++E + L
Sbjct: 914 FELTQESKKAASRNRQEITD---KDHTVSRLEEANSMLTKDI--------EILRRENEEL 962
Query: 290 NEKLICDRREFN-ETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYK 348
EK+ E+ E +E + L + K +N TER L K + + L E +N +K
Sbjct: 963 TEKMKKAEEEYKLEKEEEISNLKAAFEKNIN-TERTL--KTQAVNKLAEIMN---RKDFK 1016
Query: 349 LIENMFNKVSQIASDFKISNQLSCELDDESE 379
+ N + K + +L EL+ E E
Sbjct: 1017 IDRKKAN-TQDLRKKEKENRKLQLELNQERE 1046
>BC113114-1|AAI13115.1| 1354|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 protein.
Length = 1354
Score = 47.6 bits (108), Expect = 1e-04
Identities = 92/405 (22%), Positives = 172/405 (42%), Gaps = 41/405 (10%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMV-VPEIIDSLTEVINTLT 138
L E+ I E + K Y + LEA +R+ + H S+++ + I SL E + L
Sbjct: 585 LQERNRILENSKSQTDKDYYQLQAILEAERRD--RGHDSEMIGDLQARITSLQEEVKHLK 642
Query: 139 NGFESLEEVALEI-------DLKKNSITKD-NISIKTLLDKLITK-NETDINELRNSIKY 189
+ E +E E + +KN++ D N +K+L +L + NE + + R + K+
Sbjct: 643 HNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKH 702
Query: 190 --LESVKSEYNTANEKLFEQLNNAVDK-QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
+E KS EK ++ A +K +N + + + + +L Q
Sbjct: 703 QSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNK 762
Query: 247 XXXXXARDKFIANLEEM--KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
LE+ K +L++ +L + +N K L +++ ++E N +
Sbjct: 763 ERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKG----LEKQM---KQEINTLL 815
Query: 305 QEKNIL---LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
+ K +L L+ L+K+ E ++ E Q+QL EQ T YK +V ++
Sbjct: 816 EAKRLLEFELAQLTKQYRGNEGQMRELQDQLE--AEQYFST---LYK------TQVKELK 864
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQ 421
+ + N+ + + E +N E ++ LD + Q+ + L + K+
Sbjct: 865 EEIEEKNRENLKKIQELQNEKETLATQLDLAETKAE--SEQLARGLLEEQYFELTQESKK 922
Query: 422 IADLTEQNIILKER-LSQLETENKELLIEIQTVRGSNEEVTLNLK 465
A Q I K+ +S+LE N L +I+ +R NEE+T +K
Sbjct: 923 AASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTERMK 967
Score = 45.6 bits (103), Expect = 4e-04
Identities = 84/439 (19%), Positives = 183/439 (41%), Gaps = 46/439 (10%)
Query: 85 TIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESL 144
++ E+ + KL E +E++ LK E Q + + + +I+ L E N N ++
Sbjct: 423 SLQESLQKTIYKLEEQLHNEMQ-LKDEMEQKCRTSNIKLDKIMKELDEEGNQRRNLESTV 481
Query: 145 EEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKL 204
++ E L ++ I + + +K E +++ L+N ++ L+ V ANEKL
Sbjct: 482 SQIEKEKMLLQHRINEYQRKAEQENEKR-RNVENEVSTLKNQLEDLKKVSQNSQLANEKL 540
Query: 205 FEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMK 264
QL +++ N DLL+ E+ ++ K I+ LE +
Sbjct: 541 -SQLQKQLEEAN------DLLRTESDTAVR-----------LRKSHTEMSKSISQLESLN 582
Query: 265 TMLVEEK--LSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKV---- 318
L E L K + + ++ + E DR +E + + ++ L ++V
Sbjct: 583 RELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARITSLQEEVKHLK 642
Query: 319 ---NKTERELEEKQEQLTHLMEQLNDTE-NNSYKLIENMFNKVSQIASDFKISNQLSCEL 374
K E E +E Q+ L H ++ N+ E + +YKL +++ ++ Q ++ K++ L
Sbjct: 643 HNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKL-KSLQQRLEQEVNEHKVT---KARL 698
Query: 375 DDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKE 434
D+ ++ E S+ + ++ E + + + +A+ ++ + +Q +L
Sbjct: 699 TDKHQSIEEAKSVAMCEM------------EKKLKEEREAREKAENRVVQIEKQCSMLDV 746
Query: 435 RLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME 494
L Q + + + L + + + +TL L+ S + E +++K +
Sbjct: 747 DLKQSQQKLEHLTGNKERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKGLEKQ 806
Query: 495 WKSQFEDLDDVMKQQQKEL 513
K + L + + + EL
Sbjct: 807 MKQEINTLLEAKRLLEFEL 825
Score = 39.9 bits (89), Expect = 0.021
Identities = 91/467 (19%), Positives = 199/467 (42%), Gaps = 48/467 (10%)
Query: 24 IRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLT 81
I+L++ KE+ + + ++N+ + TV++++ ++ + I + +
Sbjct: 458 IKLDKIMKELDE-EGNQRRNL---ESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVE 513
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPE------IIDSLTEVIN 135
+++ + + DLKK+ ++S E L + Q+ ++ ++ E + S TE+
Sbjct: 514 NEVSTLKNQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSK 573
Query: 136 TLTNGFESLEEVALE----IDLKKNSITKDNISIKTLLDKLITKNETD---INELRNSIK 188
+++ ESL E ++ K+ KD ++ +L+ D I +L+ I
Sbjct: 574 SISQ-LESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARIT 632
Query: 189 YLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXX 248
L+ EK+ + A D N ++E + L+I+ L+
Sbjct: 633 SLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHK 692
Query: 249 XXXAR--DKFIANLEEMKTMLV---EEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
AR DK ++EE K++ + E+KL E +E E + + + ++ C + +
Sbjct: 693 VTKARLTDKH-QSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQ--CSMLDVDLK 749
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
++ + + + + +E++ + LT +EQ E+N L++N + A +
Sbjct: 750 QSQQKL------EHLTGNKERMEDEVKNLTLQLEQ----ESNKRLLLQNELKTQAFEADN 799
Query: 364 FK-ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
K + Q+ E++ E + L ++T Q+ E Q QL EA++
Sbjct: 800 LKGLEKQMKQEINTLLE-AKRLLEFELAQLTKQYRGNEGQMRELQD----QL--EAEQYF 852
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSST 469
+ L + + KE ++E +N+E L +IQ ++ E + L + T
Sbjct: 853 STLYKTQV--KELKEEIEEKNRENLKKIQELQNEKETLATQLDLAET 897
>BC077732-1|AAH77732.1| 662|Homo sapiens FKBP15 protein protein.
Length = 662
Score = 47.6 bits (108), Expect = 1e-04
Identities = 36/204 (17%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Query: 313 DLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSC 372
+ S ++ +R ++E + ++E+ N E + K+ E + + + + +
Sbjct: 12 ETSMIMSNIQRIIQENERLKQEILEKSNRIEEQNDKISELIERNQRYVEQSNLMMEKRNN 71
Query: 373 ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNA--QLLWEAKKQIADLTEQNI 430
L +ENT +++ L T +++L ++ QK + L E+ K+ L Q
Sbjct: 72 SLQTATENTQAKVTEELAAATAQVSHLQLKMTAHQKKETELQMQLTESLKETDLLRGQLT 131
Query: 431 ILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKT 490
++ +LS+L+ +++ + ++ + + +++ L + + + K
Sbjct: 132 KVQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEKNLSERKK 191
Query: 491 KVMEWKSQFED-LDDVMKQQQKEL 513
K + +SQ E+ +D++ K Q+EL
Sbjct: 192 KSAQERSQAEEEIDEIRKSYQEEL 215
Score = 38.7 bits (86), Expect = 0.049
Identities = 42/188 (22%), Positives = 89/188 (47%), Gaps = 20/188 (10%)
Query: 263 MKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTE 322
M+T ++ + I +++E KQEI E + ++E+N +S+L + + +
Sbjct: 11 METSMIMSNIQRIIQENERLKQEI-----------LEKSNRIEEQNDKISEL---IERNQ 56
Query: 323 RELEEKQEQLTHLMEQLND-TENNSYKLIENMFNKVSQIAS-DFKISNQLSCELDDESEN 380
R +E+ + L TEN K+ E + +Q++ K++ E + + +
Sbjct: 57 RYVEQSNLMMEKRNNSLQTATENTQAKVTEELAAATAQVSHLQLKMTAHQKKETELQMQL 116
Query: 381 TYERISLTLDKITNHITYLNTQINETQK-NDNAQLLWEAKKQIADLTEQNII-LKERLSQ 438
T E + T D + +T + +++E Q+ ++ AQ ++++KQ E + L+E L+
Sbjct: 117 T-ESLKET-DLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELTD 174
Query: 439 LETENKEL 446
L E + L
Sbjct: 175 LRVEKESL 182
Score = 37.1 bits (82), Expect = 0.15
Identities = 62/353 (17%), Positives = 143/353 (40%), Gaps = 23/353 (6%)
Query: 157 SITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQN 216
S+T + I + + ++I +NE E+ +E E N +L E+ V++ N
Sbjct: 8 SVTMETSMIMSNIQRIIQENERLKQEILEKSNRIE----EQNDKISELIERNQRYVEQSN 63
Query: 217 CIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIK 276
+ E+ N +L A+ +++L+ +K ++K +E++
Sbjct: 64 LMMEK------RNNSLQTATENTQAKVTEELAAATAQ---VSHLQ-LKMTAHQKKETELQ 113
Query: 277 EKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDL-SKKVNKTERELE--EKQEQLT 333
+ +E D+L +L + + +E + S S+K N+ + EL+ +E+LT
Sbjct: 114 MQLTESLKETDLLRGQLTKVQAKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELT 173
Query: 334 HLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKIT 393
L + E N + + + SQ + + E D+ ++ ++ D+
Sbjct: 174 DLRVEKESLEKNLSERKKKSAQERSQAEEEIDEIRKSYQEELDKLRQLLKKTRVSTDQAA 233
Query: 394 -NHITYLNTQINETQKNDNAQLLWEAK----KQIADLTEQNIILKERLSQLETENKELLI 448
++ + ++ + LL AK +Q ++ Q +++L QL+ + L
Sbjct: 234 AEQLSLVQAELQTQWEAKCEHLLASAKDEHLQQYQEVCAQRDAYQQKLVQLQEKCLALQA 293
Query: 449 EIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVME-WKSQFE 500
+I + NE+ L+ + + S +++ + +V + + +FE
Sbjct: 294 QITALTKQNEQHIKELEKNKSQMSGVEAAASDPSEKVKKIMNQVFQSLRREFE 346
Score = 33.9 bits (74), Expect = 1.4
Identities = 71/355 (20%), Positives = 138/355 (38%), Gaps = 33/355 (9%)
Query: 1 MIDNEATLFANNENIRNIIHAFKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEIN 60
++ N + NE ++ I R+EE +I +L Q+ V + + E +N+ +
Sbjct: 16 IMSNIQRIIQENERLKQEILEKSNRIEEQNDKISELIERNQRYVEQSN-LMMEKRNNSLQ 74
Query: 61 SMIR----QLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRE--NIQ 114
+ ++ L K+T + K +L+ +S E + L+ + +Q
Sbjct: 75 TATENTQAKVTEELAAATAQVSHLQLKMTAHQKKETELQMQLTESLKETDLLRGQLTKVQ 134
Query: 115 MHTSDVMVVPEIIDSL--TEVINT--LTNGFESLEEVALEIDLKKNSITKDNISIKTLLD 170
S++ E S +E N L SLEE ++ ++K S+ K+ K
Sbjct: 135 AKLSELQETSEQAQSKFKSEKQNRKQLELKVTSLEEELTDLRVEKESLEKNLSERKKKSA 194
Query: 171 KLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQ 230
+ ++ E +I+E+R S Y +KL + L + D E
Sbjct: 195 QERSQAEEEIDEIRKS----------YQEELDKLRQLLKKT-------RVSTDQAAAEQL 237
Query: 231 NLLQXXXXXXXXXXXXXXXXXARDKFIANLEEM--KTMLVEEKLSEIKEKDENFKQEIDM 288
+L+Q A+D+ + +E+ + ++KL +++EK + +I
Sbjct: 238 SLVQAELQTQWEAKCEHLLASAKDEHLQQYQEVCAQRDAYQQKLVQLQEKCLALQAQITA 297
Query: 289 L---NEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLN 340
L NE+ I + + M SD S+KV K ++ + + L E N
Sbjct: 298 LTKQNEQHIKELEKNKSQMSGVEAAASDPSEKVKKIMNQVFQSLRREFELEESYN 352
>AK027406-1|BAB55092.1| 901|Homo sapiens protein ( Homo sapiens
cDNA FLJ14500 fis, clone NT2RM1000086. ).
Length = 901
Score = 47.6 bits (108), Expect = 1e-04
Identities = 52/223 (23%), Positives = 106/223 (47%), Gaps = 17/223 (7%)
Query: 252 ARDKFIANLEEMKTML--VEEKLSEIKEK--DENFKQEIDMLNEKLICDRREFNETMQEK 307
A K A ++E+++ + +EE+ +K DE+ + I E++ +R+ T QE+
Sbjct: 592 AERKAKAEVDELRSRIRELEERNRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEE 651
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
LLS++ + T + E+ QEQ L++QL + ++ ++KL+ K +QI K+
Sbjct: 652 EALLSEM----DVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERI-KANQI---HKLL 703
Query: 368 NQLSCELDDESENTYERIS---LTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQI 422
+ EL ++ ++ LT+ K+ L + +K +Q L K++
Sbjct: 704 REEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKA 763
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
+ + LK +L ++T +E+ + R + E+ + NLK
Sbjct: 764 VEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLK 806
>AF254756-1|AAK13079.1| 698|Homo sapiens predicted testis protein
protein.
Length = 698
Score = 47.6 bits (108), Expect = 1e-04
Identities = 79/417 (18%), Positives = 167/417 (40%), Gaps = 34/417 (8%)
Query: 40 LQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYE 99
+ Q +K E + +E+ + L + E ++ E + L +
Sbjct: 128 IAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAM 187
Query: 100 DSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSIT 159
D+ SEL K EN + ++ D+ + + +E + +D K ++ T
Sbjct: 188 DTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKKYE-LQLTQEKIMCLDEKIDNFT 246
Query: 160 KDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN--EKLFEQLNNAVDKQNC 217
+ NI+ + + ++ D+ + + ++ KSE N A+ E L + +N
Sbjct: 247 RQNIAQREEIS-ILGGTLNDLAKEKECLQACLDKKSE-NIASLGESLAMKEKTISGMKNI 304
Query: 218 IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKE 277
I E ++ ++ + + +A + + +L + ++E
Sbjct: 305 IAE----MEQASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDN-DNLQE 359
Query: 278 KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLME 337
+ KQE L++KL E N+ Q+ + D + +VNK + L+ ++ + +ME
Sbjct: 360 QFAKAKQENQALSKKLNDTHNELNDIKQK----VQDTNLEVNKLKNILKSEESENRQMME 415
Query: 338 QLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHIT 397
QL ++ EN NK Q +D +N L EL +E R+ +D +
Sbjct: 416 QLRKANEDA----ENWENKARQSEAD---NNTLKLEL-ITAEAEGNRLKEKVDSLN---- 463
Query: 398 YLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVR 454
E +++ NA+ + K QI+ L + + ++E L +++ E L ++ + R
Sbjct: 464 ------REVEQHLNAERSY--KSQISTLHKSVVKMEEELQKVQFEKVSALADLSSTR 512
Score = 42.3 bits (95), Expect = 0.004
Identities = 76/388 (19%), Positives = 158/388 (40%), Gaps = 34/388 (8%)
Query: 86 IAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLE 145
+ +++ + + LYE + E+ L+RE ++ S I L V F L
Sbjct: 56 VLKSERDKIFLLYEQAQEEITRLRREMMKSCKSPKSTTAHAI--LRRVETERDVAFTDLR 113
Query: 146 EVALEIDLKKNSIT---KDNISIKTLLDKLITKNETDINELRNS----IKYLESVKSEYN 198
+ E D + + + + K L++ I + E ++ L + + + +K +
Sbjct: 114 RMTTERDSLRERLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETIS 173
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
T +++ A+D ++ E+ K EN N L+ A+ K+
Sbjct: 174 TVEKEMKSLARKAMDTES----ELGRQKAEN-NSLRLLYENTEKDLSDTQRHLAKKKYEL 228
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK- 317
L + K M ++EK+ ++ ++EI +L L N+ +EK L + L KK
Sbjct: 229 QLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTL-------NDLAKEKECLQACLDKKS 281
Query: 318 --VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+ L K++ ++ + + + E S + E + ++ ++ QL D
Sbjct: 282 ENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVS---RMRRQLDETND 338
Query: 376 DESENTYERISLTLDKITNHITYLNT-QINET---QKNDNAQLLWEAKKQIADLTEQNII 431
+ ++ ER L D + Q N+ + ND L + K+++ D +
Sbjct: 339 ELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNK 398
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEE 459
LK L E+EN++++ + +R +NE+
Sbjct: 399 LKNILKSEESENRQMM---EQLRKANED 423
Score = 42.3 bits (95), Expect = 0.004
Identities = 54/265 (20%), Positives = 105/265 (39%), Gaps = 15/265 (5%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
+ NL++ + M ++ +KE ++E+ L K + E E N L
Sbjct: 151 VHNLDDER-MEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENN----SLRL 205
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
TE++L + Q L +L T+ L E + N Q + + + L L+D
Sbjct: 206 LYENTEKDLSDTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLND 265
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQ--LLWEAKKQIADLTEQNIILKE 434
++ E + LDK + +I L + +K + ++ E ++ TE I+ ++
Sbjct: 266 LAKEK-ECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQ 324
Query: 435 RLS----QLETENKELLI---EIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED 487
+S QL+ N EL E + N+ + + NE+ D
Sbjct: 325 DVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELND 384
Query: 488 MKTKVMEWKSQFEDLDDVMKQQQKE 512
+K KV + + L +++K ++ E
Sbjct: 385 IKQKVQDTNLEVNKLKNILKSEESE 409
Score = 41.1 bits (92), Expect = 0.009
Identities = 65/322 (20%), Positives = 129/322 (40%), Gaps = 23/322 (7%)
Query: 57 DEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMH 116
DE N + Q+ L E+ A+ ++ L K D+ +EL +K++ +Q
Sbjct: 334 DETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQK-VQDT 392
Query: 117 TSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKN 176
+V + I+ S + E A + K DN ++K +LIT
Sbjct: 393 NLEVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKL---ELITA- 448
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E + N L+ + L ++ A Q++ ++EE+ ++ E + L
Sbjct: 449 EAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALADL 508
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD-ENFKQEIDMLNEKLIC 295
K + N + ++ +++ E++E + ++ EI++L ++
Sbjct: 509 SSTRELCIKLDSS-----KELLN----RQLVAKDQEIEMRENELDSAHSEIELLRSQMAN 559
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN---SYKLIEN 352
+R +MQ LL K +++ L+EK+ ++ L E L EN + +
Sbjct: 560 ERI----SMQNLEALLVANRDKEYQSQIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQ 615
Query: 353 MFNKVSQIASDFKIS-NQLSCE 373
N V+Q+ +D I+ QL E
Sbjct: 616 FRNVVTQLEADLDITKRQLGTE 637
>AC019097-1|AAY14820.1| 698|Homo sapiens unknown protein.
Length = 698
Score = 47.6 bits (108), Expect = 1e-04
Identities = 79/417 (18%), Positives = 167/417 (40%), Gaps = 34/417 (8%)
Query: 40 LQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYE 99
+ Q +K E + +E+ + L + E ++ E + L +
Sbjct: 128 IAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAM 187
Query: 100 DSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSIT 159
D+ SEL K EN + ++ D+ + + +E + +D K ++ T
Sbjct: 188 DTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKKYE-LQLTQEKIMCLDEKIDNFT 246
Query: 160 KDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN--EKLFEQLNNAVDKQNC 217
+ NI+ + + ++ D+ + + ++ KSE N A+ E L + +N
Sbjct: 247 RQNIAQREEIS-ILGGTLNDLAKEKECLQACLDKKSE-NIASLGESLAMKEKTISGMKNI 304
Query: 218 IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKE 277
I E ++ ++ + + +A + + +L + ++E
Sbjct: 305 IAE----MEQASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDN-DNLQE 359
Query: 278 KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLME 337
+ KQE L++KL E N+ Q+ + D + +VNK + L+ ++ + +ME
Sbjct: 360 QFAKAKQENQALSKKLNDTHNELNDIKQK----VQDTNLEVNKLKNILKSEESENRQMME 415
Query: 338 QLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHIT 397
QL ++ EN NK Q +D +N L EL +E R+ +D +
Sbjct: 416 QLRKANEDA----ENWENKARQSEAD---NNTLKLEL-ITAEAEGNRLKEKVDSLN---- 463
Query: 398 YLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVR 454
E +++ NA+ + K QI+ L + + ++E L +++ E L ++ + R
Sbjct: 464 ------REVEQHLNAERSY--KSQISTLHKSVVKMEEELQKVQFEKVSALADLSSTR 512
Score = 42.3 bits (95), Expect = 0.004
Identities = 76/388 (19%), Positives = 158/388 (40%), Gaps = 34/388 (8%)
Query: 86 IAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLE 145
+ +++ + + LYE + E+ L+RE ++ S I L V F L
Sbjct: 56 VLKSERDKIFLLYEQAQEEITRLRREMMKSCKSPKSTTAHAI--LRRVETERDVAFTDLR 113
Query: 146 EVALEIDLKKNSIT---KDNISIKTLLDKLITKNETDINELRNS----IKYLESVKSEYN 198
+ E D + + + + K L++ I + E ++ L + + + +K +
Sbjct: 114 RMTTERDSLRERLKIAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETIS 173
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
T +++ A+D ++ E+ K EN N L+ A+ K+
Sbjct: 174 TVEKEMKSLARKAMDTES----ELGRQKAEN-NSLRLLYENTEKDLSDTQRHLAKKKYEL 228
Query: 259 NLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKK- 317
L + K M ++EK+ ++ ++EI +L L N+ +EK L + L KK
Sbjct: 229 QLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTL-------NDLAKEKECLQACLDKKS 281
Query: 318 --VNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELD 375
+ L K++ ++ + + + E S + E + ++ ++ QL D
Sbjct: 282 ENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQDVS---RMRRQLDETND 338
Query: 376 DESENTYERISLTLDKITNHITYLNT-QINET---QKNDNAQLLWEAKKQIADLTEQNII 431
+ ++ ER L D + Q N+ + ND L + K+++ D +
Sbjct: 339 ELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQKVQDTNLEVNK 398
Query: 432 LKERLSQLETENKELLIEIQTVRGSNEE 459
LK L E+EN++++ + +R +NE+
Sbjct: 399 LKNILKSEESENRQMM---EQLRKANED 423
Score = 42.3 bits (95), Expect = 0.004
Identities = 54/265 (20%), Positives = 105/265 (39%), Gaps = 15/265 (5%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
+ NL++ + M ++ +KE ++E+ L K + E E N L
Sbjct: 151 VHNLDDER-MEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENN----SLRL 205
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
TE++L + Q L +L T+ L E + N Q + + + L L+D
Sbjct: 206 LYENTEKDLSDTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLND 265
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQ--LLWEAKKQIADLTEQNIILKE 434
++ E + LDK + +I L + +K + ++ E ++ TE I+ ++
Sbjct: 266 LAKEK-ECLQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQ 324
Query: 435 RLS----QLETENKELLI---EIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED 487
+S QL+ N EL E + N+ + + NE+ D
Sbjct: 325 DVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELND 384
Query: 488 MKTKVMEWKSQFEDLDDVMKQQQKE 512
+K KV + + L +++K ++ E
Sbjct: 385 IKQKVQDTNLEVNKLKNILKSEESE 409
Score = 41.1 bits (92), Expect = 0.009
Identities = 65/322 (20%), Positives = 129/322 (40%), Gaps = 23/322 (7%)
Query: 57 DEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMH 116
DE N + Q+ L E+ A+ ++ L K D+ +EL +K++ +Q
Sbjct: 334 DETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQK-VQDT 392
Query: 117 TSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKN 176
+V + I+ S + E A + K DN ++K +LIT
Sbjct: 393 NLEVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKL---ELITA- 448
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E + N L+ + L ++ A Q++ ++EE+ ++ E + L
Sbjct: 449 EAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALADL 508
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD-ENFKQEIDMLNEKLIC 295
K + N + ++ +++ E++E + ++ EI++L ++
Sbjct: 509 SSTRELCIKLDSS-----KELLN----RQLVAKDQEIEMRENELDSAHSEIELLRSQMAN 559
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN---SYKLIEN 352
+R +MQ LL K +++ L+EK+ ++ L E L EN + +
Sbjct: 560 ERI----SMQNLEALLVANRDKEYQSQIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQ 615
Query: 353 MFNKVSQIASDFKIS-NQLSCE 373
N V+Q+ +D I+ QL E
Sbjct: 616 FRNVVTQLEADLDITKRQLGTE 637
>AB208965-1|BAD92202.1| 705|Homo sapiens Rho-associated,
coiled-coil containing protein kinase 1 variant protein.
Length = 705
Score = 47.6 bits (108), Expect = 1e-04
Identities = 92/405 (22%), Positives = 172/405 (42%), Gaps = 41/405 (10%)
Query: 80 LTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMV-VPEIIDSLTEVINTLT 138
L E+ I E + K Y + LEA +R+ + H S+++ + I SL E + L
Sbjct: 263 LQERNRILENSKSQTDKDYYQLQAILEAERRD--RGHDSEMIGDLQARITSLQEEVKHLK 320
Query: 139 NGFESLEEVALEI-------DLKKNSITKD-NISIKTLLDKLITK-NETDINELRNSIKY 189
+ E +E E + +KN++ D N +K+L +L + NE + + R + K+
Sbjct: 321 HNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHKVTKARLTDKH 380
Query: 190 --LESVKSEYNTANEKLFEQLNNAVDK-QNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
+E KS EK ++ A +K +N + + + + +L Q
Sbjct: 381 QSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQCSMLDVDLKQSQQKLEHLTGNK 440
Query: 247 XXXXXARDKFIANLEEM--KTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETM 304
LE+ K +L++ +L + +N K L +++ ++E N +
Sbjct: 441 ERMEDEVKNLTLQLEQESNKRLLLQNELKTQAFEADNLKG----LEKQM---KQEINTLL 493
Query: 305 QEKNIL---LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIA 361
+ K +L L+ L+K+ E ++ E Q+QL EQ T YK +V ++
Sbjct: 494 EAKRLLEFELAQLTKQYRGNEGQMRELQDQLE--AEQYFST---LYK------TQVKELK 542
Query: 362 SDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQ 421
+ + N+ + + E +N E ++ LD + Q+ + L + K+
Sbjct: 543 EEIEEKNRENLKKIQELQNEKETLATQLDLAETKAE--SEQLARGLLEEQYFELTQESKK 600
Query: 422 IADLTEQNIILKER-LSQLETENKELLIEIQTVRGSNEEVTLNLK 465
A Q I K+ +S+LE N L +I+ +R NEE+T +K
Sbjct: 601 AASRNRQEITDKDHTVSRLEEANSMLTKDIEILRRENEELTEKMK 645
Score = 39.5 bits (88), Expect = 0.028
Identities = 91/467 (19%), Positives = 199/467 (42%), Gaps = 48/467 (10%)
Query: 24 IRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDE--INSMIRQLXXXXXXXXXXXXXLT 81
I+L++ KE+ + + ++N+ + TV++++ ++ + I + +
Sbjct: 136 IKLDKIMKELDE-EGNQRRNL---ESTVSQIEKEKMLLQHRINEYQRKAEQENEKRRNVE 191
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPE------IIDSLTEVIN 135
+++ + + DLKK+ ++S E L + Q+ ++ ++ E + S TE+
Sbjct: 192 NEVSTLKDQLEDLKKVSQNSQLANEKLSQLQKQLEEANDLLRTESDTAVRLRKSHTEMSK 251
Query: 136 TLTNGFESLEEVALE----IDLKKNSITKDNISIKTLLDKLITKNETD---INELRNSIK 188
+++ ESL E ++ K+ KD ++ +L+ D I +L+ I
Sbjct: 252 SISQ-LESLNRELQERNRILENSKSQTDKDYYQLQAILEAERRDRGHDSEMIGDLQARIT 310
Query: 189 YLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXX 248
L+ EK+ + A D N ++E + L+I+ L+
Sbjct: 311 SLQEEVKHLKHNLEKVEGERKEAQDMLNHSEKEKNNLEIDLNYKLKSLQQRLEQEVNEHK 370
Query: 249 XXXAR--DKFIANLEEMKTMLV---EEKLSEIKEKDENFKQEIDMLNEKLICDRREFNET 303
AR DK ++EE K++ + E+KL E +E E + + + ++ C + +
Sbjct: 371 VTKARLTDKH-QSIEEAKSVAMCEMEKKLKEEREAREKAENRVVQIEKQ--CSMLDVDLK 427
Query: 304 MQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASD 363
++ + + + + +E++ + LT +EQ E+N L++N + A +
Sbjct: 428 QSQQKL------EHLTGNKERMEDEVKNLTLQLEQ----ESNKRLLLQNELKTQAFEADN 477
Query: 364 FK-ISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQI 422
K + Q+ E++ E + L ++T Q+ E Q QL EA++
Sbjct: 478 LKGLEKQMKQEINTLLE-AKRLLEFELAQLTKQYRGNEGQMRELQD----QL--EAEQYF 530
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSST 469
+ L + + KE ++E +N+E L +IQ ++ E + L + T
Sbjct: 531 STLYKTQV--KELKEEIEEKNRENLKKIQELQNEKETLATQLDLAET 575
>X06825-1|CAA29971.1| 284|Homo sapiens protein ( Human mRNA for
skeletal beta-tropomyosin. ).
Length = 284
Score = 47.2 bits (107), Expect = 1e-04
Identities = 57/301 (18%), Positives = 133/301 (44%), Gaps = 34/301 (11%)
Query: 216 NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEI 275
+ I++++ +LK++ +N + A D+ LEE + L ++KL
Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQ------AEDR-CKQLEEEQQAL-QKKLKGT 53
Query: 276 KEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL 335
+++ E + + + EKL ++ E T E ++ + L++++ E EL+ QE+L
Sbjct: 54 EDEVEKYSESVKEAQEKL--EQAEKKATDAEADV--ASLNRRIQLVEEELDRAQERLATA 109
Query: 336 MEQLNDTE------NNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+++L + E K+IEN K + ++ + + + ++S+ YE
Sbjct: 110 LQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE------ 163
Query: 390 DKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIE 449
++ + L ++ ++ + A++ A+ + DL E+ I+ L LE + + +
Sbjct: 164 -EVARKLVILEGELERSE--ERAEV---AESKCGDLEEELKIVTNNLKSLEAQADKYSTK 217
Query: 450 IQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKV----MEWKSQFEDLDDV 505
+ + LK++ T I+D++ +V M++K+ E+LD+
Sbjct: 218 EDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNA 277
Query: 506 M 506
+
Sbjct: 278 L 278
>U25725-1|AAA86889.1| 1017|Homo sapiens AH antigen protein.
Length = 1017
Score = 47.2 bits (107), Expect = 1e-04
Identities = 47/252 (18%), Positives = 111/252 (44%), Gaps = 14/252 (5%)
Query: 268 VEEKLSEIKEKDENFKQ-EIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELE 326
VE ++I+E + K E+D++ L ++ + +QEK LS+L K ++ + +LE
Sbjct: 87 VETLKTQIEEMARSLKVFELDLVT--LRSEKENLTKQIQEKQGQLSELDKLLSSFKSQLE 144
Query: 327 EKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESE------N 380
EK++ + E+ ++ + V+ + D +I LD E N
Sbjct: 145 EKEQAEIQIKEESKTAVEMLQNQLKELNEAVAALCGDQEIMKATEQSLDPPIEEEHQLRN 204
Query: 381 TYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLE 440
+ E++ L+ + Q+ E++ +A LL K ++ +L + I +
Sbjct: 205 SIEKLRARLEADEKKQLCVLQQLKESE--HHADLL---KGRVENLERELEIARTNQEHAA 259
Query: 441 TENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKVMEWKSQFE 500
E + E++T++ E +T +L+ +NE++ + ++ E +
Sbjct: 260 LEAENSKGEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEIINS 319
Query: 501 DLDDVMKQQQKE 512
+++++++++E
Sbjct: 320 SFENILQEKEQE 331
Score = 41.1 bits (92), Expect = 0.009
Identities = 103/505 (20%), Positives = 199/505 (39%), Gaps = 60/505 (11%)
Query: 22 FKIRLEECYKEIGQLKSGLQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLT 81
F +RL +E+ QL+ G+ +K ++ DE + +
Sbjct: 6 FALRLSSTQEEVHQLRRGI-------EKLRVRIEADEKKQL----------------HIA 42
Query: 82 EKLTIAETKHNDLKKLYEDSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGF 141
EKL + +++ LK E+ EL+ + EN ++ D +++L I +
Sbjct: 43 EKLKERDGENDSLKDKVENLERELQ-MSEENQELVILDAENSKAEVETLKTQIEEMARSL 101
Query: 142 ESLEEVALEIDLKKNSITK---DNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYN 198
+ E + + +K ++TK + + LDKL++ ++ + E + +K E
Sbjct: 102 KVFELDLVTLRSEKENLTKQIQEKQGQLSELDKLLSSFKSQLEEKEQA---EIQIKEESK 158
Query: 199 TANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIA 258
TA E L QL + + + +++K Q+L + +K A
Sbjct: 159 TAVEMLQNQLKELNEAVAALCGDQEIMKATEQSL-------DPPIEEEHQLRNSIEKLRA 211
Query: 259 NLE--EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
LE E K + V ++L E + + K ++ L +L E T QE L ++ SK
Sbjct: 212 RLEADEKKQLCVLQQLKESEHHADLLKGRVENLEREL-----EIARTNQEHAALEAENSK 266
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
+T + E Q +E T + + + N K + S+ +I N +
Sbjct: 267 GEVETLKAKIEGMTQSLRGLELDVVTIRSEKEDLTNELQKEQERISELEIINSSFENILQ 326
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERL 436
E E E++ + +K + + L TQ+ + + ++ KK ++ EQN L ++
Sbjct: 327 EKEQ--EKVQMK-EKSSTAMEMLQTQLKSSMREWQPCIM--TKKPVS-AKEQN--LSSQV 378
Query: 437 SQLETENKELLIEIQ-------TVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMK 489
LE E +LL + ++ S + ++D N+I+D +
Sbjct: 379 ECLELEKAQLLQGLDEAKNNYIVLQSSVNGLIQEVEDGKQKLEKKDEEISRLKNQIQDQE 438
Query: 490 TKVMEWKSQFEDLDDVMKQQQKELK 514
V + SQ E + K+Q EL+
Sbjct: 439 QLVSK-LSQVEGEHQLWKEQNLELR 462
Score = 38.7 bits (86), Expect = 0.049
Identities = 64/330 (19%), Positives = 128/330 (38%), Gaps = 11/330 (3%)
Query: 180 INELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXX 239
I E+ + + LE E + ++ +Q V K + ++ E L K +N L
Sbjct: 410 IQEVEDGKQKLEKKDEEISRLKNQIQDQ-EQLVSKLSQVEGEHQLWKEQNLELRNLTVEL 468
Query: 240 XXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRRE 299
+ + L+ L E +L K +F ++++ + K +RE
Sbjct: 469 EQKIQVLQSKNASLQDTLEVLQSSYKNL-ENELELTKMDKMSFVEKVNKMTAKETELQRE 527
Query: 300 FNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLND--TENNSYKLIENMFNKV 357
+E Q+ L +LS + N+ EL+ E++ +QL + EN+ K + +K
Sbjct: 528 MHEMAQKTAELQEELSGEKNRLAGELQLLLEEIKSSKDQLKELTLENSELKKSLDCMHK- 586
Query: 358 SQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
Q+ + K+ +++ E + +L LD TN + Q + + L
Sbjct: 587 DQVEKEGKVREEIAEYQLRLHEAEKKHQALLLD--TNKQYEVEIQTYREKLTSKEECLSS 644
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
K +I DL + + KE L+ ++L E++ + N + LK +
Sbjct: 645 QKLEI-DLLKSS---KEELNNSLKATTQILEELKKTKMDNLKYVNQLKKENERAQGKMKL 700
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMK 507
++E+ K + + SQ + + K
Sbjct: 701 LIKSCKQLEEEKEILQKELSQLQAAQEKQK 730
Score = 33.1 bits (72), Expect = 2.4
Identities = 37/141 (26%), Positives = 59/141 (41%), Gaps = 13/141 (9%)
Query: 137 LTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSE 196
LT+ E L LEIDL K+S + N S+K L +T ++ L KY+ +K E
Sbjct: 635 LTSKEECLSSQKLEIDLLKSSKEELNNSLKATTQILEELKKTKMDNL----KYVNQLKKE 690
Query: 197 YNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKF 256
NE+ ++ + ++EE ++L+ E L D+
Sbjct: 691 ----NERAQGKMKLLIKSCKQLEEEKEILQKE----LSQLQAAQEKQKTGTVMDTKVDEL 742
Query: 257 IANLEEMKTMLVEEKLSEIKE 277
++E+K L EEK E E
Sbjct: 743 TTEIKELKETL-EEKTKEADE 762
>CR769776-10|CAI95382.1| 354|Homo sapiens coiled-coil domain
containing 29 protein.
Length = 354
Score = 47.2 bits (107), Expect = 1e-04
Identities = 85/367 (23%), Positives = 142/367 (38%), Gaps = 40/367 (10%)
Query: 142 ESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN 201
E L E E +K N++ + L K ET N L + + + +K Y A
Sbjct: 2 EFLTEQLSETQIKFNALKDKFRKTRDSLRKKSLALETVQNNLSQTQQQTQEMKEMYQNAE 61
Query: 202 EKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLE 261
K+ NN+ K NC++E + L+ EN L+Q + FI E
Sbjct: 62 AKV----NNSTGKWNCVEERICHLQRENAWLVQQLDDVHQKEDHKEIVTNIQRGFI---E 114
Query: 262 EMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKT 321
K V ++EK + E D L E L RE E + L +++ V K
Sbjct: 115 SGKKDFV------LEEKSKKLMNECDHLKESLFQYEREKTEVVVVVRQLQQEVADSVKKL 168
Query: 322 ERELEEKQEQLTHLMEQLNDTENNSYKLI-------------ENMFNKVSQIASDFKISN 368
LE E ++ L++T+ ++ KL E + +K +A D ++
Sbjct: 169 -TTLESPLEGISRCHINLDETQASNKKLFQVKSQFDDLTAQKEALSSKCVNLAKDNQVLQ 227
Query: 369 Q--LSC-ELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADL 425
Q LS ++ + E E + ++I N T++ E K +L + K A
Sbjct: 228 QEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVEISKLQEYKLELDEKAMQAVE 287
Query: 426 TEQNIILKERL---SQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXS 482
+ I L+E+ QLE NK+ + + + +E+T LKD +
Sbjct: 288 KLEEIHLQEQAQYEKQLEQLNKDNMASL-----NKKELT--LKDVECKFSEMKTAYEEVT 340
Query: 483 NEIEDMK 489
E+E+ K
Sbjct: 341 TELEEYK 347
Score = 34.7 bits (76), Expect = 0.80
Identities = 30/129 (23%), Positives = 57/129 (44%), Gaps = 1/129 (0%)
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILL 311
A+D + E + V+++ +++E + K+EI L + +R E ++ + K L
Sbjct: 220 AKDNQVLQQEFLSMKKVQQQCEKLEEDKKMLKEEILNLKTHMENNRVEISKLQEYKLELD 279
Query: 312 SDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS-NQL 370
+ V K E ++Q Q +EQLN S E V S+ K + ++
Sbjct: 280 EKAMQAVEKLEEIHLQEQAQYEKQLEQLNKDNMASLNKKELTLKDVECKFSEMKTAYEEV 339
Query: 371 SCELDDESE 379
+ EL++ E
Sbjct: 340 TTELEEYKE 348
>BC127772-1|AAI27773.1| 863|Homo sapiens KIF5C protein protein.
Length = 863
Score = 47.2 bits (107), Expect = 1e-04
Identities = 64/319 (20%), Positives = 132/319 (41%), Gaps = 24/319 (7%)
Query: 127 IDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS 186
I + + +L N + LE ++ + K N+ ++ + + L I+++E I L +
Sbjct: 497 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLL----ISQHEAKIKSLTDY 552
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
++ +E + + + + L E+L ++ EV E ++L +
Sbjct: 553 MQNMEQKRRQLEESQDSLSEELAKLRAQEK--MHEVSFQDKEKEHLTRLQDAEEMKKALE 610
Query: 247 XXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQE 306
R+ L ++ +EEK +I ++ + Q++ + EKL D + QE
Sbjct: 611 QQMESHREAHQKQLSRLRDE-IEEK-QKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQE 668
Query: 307 KNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI 366
+ + L L L +K+EQ ++ L +T + + + N+ K+ D
Sbjct: 669 REMKLEKLLL--------LNDKREQAREDLKGLEETVSRELQTLHNL-RKL--FVQDLTT 717
Query: 367 SNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLT 426
+ S ELD++ + + N++ L T++++ DNA L E K L
Sbjct: 718 RVKKSVELDNDDGGGSAAQKQKISFLENNLEQL-TKVHKQLVRDNADLRCELPK----LE 772
Query: 427 EQNIILKERLSQLETENKE 445
++ ER+ LE+ KE
Sbjct: 773 KRLRATAERVKALESALKE 791
Score = 34.3 bits (75), Expect = 1.1
Identities = 41/214 (19%), Positives = 95/214 (44%), Gaps = 18/214 (8%)
Query: 298 REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV 357
+E N+T+ KN++ L ++N+ +++ +Q N ++ +I+N+ V
Sbjct: 256 KEKNKTL--KNVI-QHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVV 312
Query: 358 SQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
+ I+++ K + D+E + Y ++ D+I N + L ++ + Q D +LL
Sbjct: 313 AGISTEEKE------KYDEEISSLYRQLDDKDDEI-NQQSQLAEKLKQ-QMLDQDELLAS 364
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
++ + E+ L++L+ EN+ E++ V + EE+ +N S
Sbjct: 365 TRRDYEKIQEE-------LTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRA 417
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
++E+ T + + + L ++ Q+K
Sbjct: 418 NEQLTDELAQKTTTLTTTQRELSQLQELSNHQKK 451
>BC110287-1|AAI10288.1| 725|Homo sapiens KIF5C protein protein.
Length = 725
Score = 47.2 bits (107), Expect = 1e-04
Identities = 64/319 (20%), Positives = 132/319 (41%), Gaps = 24/319 (7%)
Query: 127 IDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS 186
I + + +L N + LE ++ + K N+ ++ + + L I+++E I L +
Sbjct: 359 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLL----ISQHEAKIKSLTDY 414
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
++ +E + + + + L E+L ++ EV E ++L +
Sbjct: 415 MQNMEQKRRQLEESQDSLSEELAKLRAQEK--MHEVSFQDKEKEHLTRLQDAEEMKKALE 472
Query: 247 XXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQE 306
R+ L ++ +EEK +I ++ + Q++ + EKL D + QE
Sbjct: 473 QQMESHREAHQKQLSRLRDE-IEEK-QKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQE 530
Query: 307 KNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI 366
+ + L L L +K+EQ ++ L +T + + + N+ K+ D
Sbjct: 531 REMKLEKLLL--------LNDKREQAREDLKGLEETVSRELQTLHNL-RKL--FVQDLTT 579
Query: 367 SNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLT 426
+ S ELD++ + + N++ L T++++ DNA L E K L
Sbjct: 580 RVKKSVELDNDDGGGSAAQKQKISFLENNLEQL-TKVHKQLVRDNADLRCELPK----LE 634
Query: 427 EQNIILKERLSQLETENKE 445
++ ER+ LE+ KE
Sbjct: 635 KRLRATAERVKALESALKE 653
Score = 34.3 bits (75), Expect = 1.1
Identities = 41/214 (19%), Positives = 95/214 (44%), Gaps = 18/214 (8%)
Query: 298 REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV 357
+E N+T+ KN++ L ++N+ +++ +Q N ++ +I+N+ V
Sbjct: 118 KEKNKTL--KNVI-QHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVV 174
Query: 358 SQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
+ I+++ K + D+E + Y ++ D+I N + L ++ + Q D +LL
Sbjct: 175 AGISTEEKE------KYDEEISSLYRQLDDKDDEI-NQQSQLAEKLKQ-QMLDQDELLAS 226
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
++ + E+ L++L+ EN+ E++ V + EE+ +N S
Sbjct: 227 TRRDYEKIQEE-------LTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRA 279
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
++E+ T + + + L ++ Q+K
Sbjct: 280 NEQLTDELAQKTTTLTTTQRELSQLQELSNHQKK 313
>BC091490-1|AAH91490.1| 620|Homo sapiens ODF2L protein protein.
Length = 620
Score = 47.2 bits (107), Expect = 1e-04
Identities = 76/372 (20%), Positives = 154/372 (41%), Gaps = 40/372 (10%)
Query: 111 ENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLD 170
E I +++ + I E++ + F+S++ +ALE L+K + ++ ++L
Sbjct: 76 EKINFENANLSALNLKISEQKEILIKELDTFKSVK-LALEHLLRKRDYKQTGDNLSSMLL 134
Query: 171 KLITKNETDINELRNSIKYLES--------VKSE-YNTANEKLFEQLNNAVDKQNCIQEE 221
+ +T NE++ L+ + E+ +SE NT F Q V ++ +Q +
Sbjct: 135 ENLTDNESENTNLKKKVFEKEAHIQELSCLFQSEKANTLKANRFSQSVKVVHER--LQIQ 192
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE---MKTMLVEEKLSEIKEK 278
+ + EN L + ++E KT+ +++ K++
Sbjct: 193 IHKREAENDKLKEYVKSLETKIAKWNLQSRMNKNEAIVMKEASRQKTVALKKASKVYKQR 252
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK-KVNKTERE--LEEKQEQLTHL 335
++F I+ L ++ + +ET+ N S K + KTE E +E ++Q+ +L
Sbjct: 253 LDHFTGAIEKLTSQIRDQEAKLSETISASNAWKSHYEKIVIEKTELEVQIETMKKQIINL 312
Query: 336 MEQLNDTENNSYKLIENMFNKVSQI--------ASDFKISNQLSCELDDESENTYERISL 387
+E L E++ E + KV I + K+ + C + ES+N I L
Sbjct: 313 LEDLKKMEDHGKNSCEEILRKVHSIEYENETLNLENTKLKLRFPCRI-TESKNMNILIVL 371
Query: 388 -----------TLDKITNHITYLNTQINETQKNDNAQ--LLWEAKKQIADLTEQNIILKE 434
TL + + + + +++E Q+ + Q L+ K Q+ L E I+K
Sbjct: 372 DMLCYISSEKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKS 431
Query: 435 RLSQLETENKEL 446
R L +N ++
Sbjct: 432 RCENLLHKNNQI 443
Score = 39.1 bits (87), Expect = 0.037
Identities = 46/242 (19%), Positives = 97/242 (40%), Gaps = 8/242 (3%)
Query: 117 TSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNIS---IKTLLDKLI 173
+S+ + + D + V N L+ E ++ I++ K + K + +K+ + L+
Sbjct: 378 SSEKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKSRCENLL 437
Query: 174 TKNETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVD-KQNCIQEEVDLLKIENQNL 232
KN I + +N K +E V +N + E+ N + K +Q++++ + EN+ L
Sbjct: 438 HKNN-QITKTKN--KNVEKVDGNHNLLTKLSLEEENCLIQLKCENLQQKLEQMDAENKEL 494
Query: 233 LQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEK 292
+ + L +EE ++ E+ E L K
Sbjct: 495 EKKLANQEECLKHSNLKFKEKSAEYTALARQLEAALEEGRQKVAEEIEKMSSRESALQIK 554
Query: 293 LICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIEN 352
++ E + +E+N L+ ++ K E L+E Q L E N++ N + ++
Sbjct: 555 ILDLETELRKKNEEQNQLVCKMNSKAQHQEVCLKEVQNSL-EKSENQNESIKNYLQFLKT 613
Query: 353 MF 354
+
Sbjct: 614 SY 615
>BC030802-1|AAH30802.2| 661|Homo sapiens Similar to ring finger
protein 40 protein.
Length = 661
Score = 47.2 bits (107), Expect = 1e-04
Identities = 51/223 (22%), Positives = 105/223 (47%), Gaps = 17/223 (7%)
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEK----DENFKQEIDMLNEKLICDRREFNETMQEK 307
A K A ++E+++ + E + + +E DE+ + I E++ +R+ T QE+
Sbjct: 352 AERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEE 411
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
LLS++ + T + E+ QEQ L++QL + ++ ++KL+ K +QI K+
Sbjct: 412 EALLSEM----DVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERI-KANQI---HKLL 463
Query: 368 NQLSCELDDESENTYERIS---LTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQI 422
+ EL ++ ++ LT+ K+ L + +K +Q L K++
Sbjct: 464 REEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKA 523
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
+ + LK +L ++T +E+ + R + E+ + NLK
Sbjct: 524 VEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLK 566
>BC028366-1|AAH28366.1| 698|Homo sapiens testis specific, 10
protein.
Length = 698
Score = 47.2 bits (107), Expect = 1e-04
Identities = 79/417 (18%), Positives = 167/417 (40%), Gaps = 34/417 (8%)
Query: 40 LQQNVGVGDKTVAELKNDEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYE 99
+ Q +K E + +E+ + L + E ++ E + L +
Sbjct: 128 IAQETAFNEKAHLEQRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAM 187
Query: 100 DSASELEALKRENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSIT 159
D+ SEL K EN + ++ D+ + + +E + +D K ++ T
Sbjct: 188 DTESELGRQKAENNSLRLLYENTEKDLSDTQRHLAKKKYE-LQLTQEKIMCLDEKIDNFT 246
Query: 160 KDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTAN--EKLFEQLNNAVDKQNC 217
+ NI+ + + ++ D+ + + ++ KSE N A+ E L + +N
Sbjct: 247 RQNIAQREEIS-ILGGTLNDLAKEKECMQACLDKKSE-NIASLGESLAMKEKTISGMKNI 304
Query: 218 IQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKE 277
I E ++ ++ + + +A + + +L + ++E
Sbjct: 305 IAE----MEQASRQCTEALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDN-DNLQE 359
Query: 278 KDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLME 337
+ KQE L++KL E N+ Q+ + D + +VNK + L+ ++ + +ME
Sbjct: 360 QFAKAKQENQALSKKLNDTHNELNDIKQK----VQDTNLEVNKLKNILKSEESENRQMME 415
Query: 338 QLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTLDKITNHIT 397
QL ++ EN NK Q +D +N L EL +E R+ +D +
Sbjct: 416 QLRKANEDA----ENWENKARQSEAD---NNTLKLEL-ITAEAEGNRLKEKVDSLN---- 463
Query: 398 YLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVR 454
E +++ NA+ + K QI+ L + + ++E L +++ E L ++ + R
Sbjct: 464 ------REVEQHLNAERSY--KSQISTLHKSVVKMEEELQKVQFEKVSALADLSSTR 512
Score = 41.9 bits (94), Expect = 0.005
Identities = 54/265 (20%), Positives = 105/265 (39%), Gaps = 15/265 (5%)
Query: 257 IANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK 316
+ NL++ + M ++ +KE ++E+ L K + E E N L
Sbjct: 151 VHNLDDER-MEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENN----SLRL 205
Query: 317 KVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQLSCELDD 376
TE++L + Q L +L T+ L E + N Q + + + L L+D
Sbjct: 206 LYENTEKDLSDTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGGTLND 265
Query: 377 ESENTYERISLTLDKITNHITYLNTQINETQKNDNAQ--LLWEAKKQIADLTEQNIILKE 434
++ E + LDK + +I L + +K + ++ E ++ TE I+ ++
Sbjct: 266 LAKEK-ECMQACLDKKSENIASLGESLAMKEKTISGMKNIIAEMEQASRQCTEALIVCEQ 324
Query: 435 RLS----QLETENKELLI---EIQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIED 487
+S QL+ N EL E + N+ + + NE+ D
Sbjct: 325 DVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELND 384
Query: 488 MKTKVMEWKSQFEDLDDVMKQQQKE 512
+K KV + + L +++K ++ E
Sbjct: 385 IKQKVQDTNLEVNKLKNILKSEESE 409
Score = 41.5 bits (93), Expect = 0.007
Identities = 83/409 (20%), Positives = 169/409 (41%), Gaps = 54/409 (13%)
Query: 96 KLYEDSASELEALK--RENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVA-LEID 152
+L + + + E LK E + H +++ +++ S + I L ++ EE+ L +
Sbjct: 24 ELLKTTTRDREELKCMLEKYERHLAEIQGNVKVLKSERDKIFLLYE--QAQEEITRLRRE 81
Query: 153 LKKNSITKDNISIKTLLDKLITKNETDINELRNSIKYLESVKSEYNTANEKLFEQ---LN 209
+ K+ + + + +L ++ T+ + +LR +S++ A E F + L
Sbjct: 82 MMKSCKSPKSTTAHAILRRVETERDVAFTDLRRMTTERDSLRERLKIAQETAFNEKAHLE 141
Query: 210 NAVDKQNCIQEEVDLLKIE---NQNLLQXXXXXX-------XXXXXXXXXXXARDKFIAN 259
+++ C +D ++E N L++ R K N
Sbjct: 142 QRIEELECTVHNLDDERMEQMSNMTLMKETISTVEKEMKSLARKAMDTESELGRQKAENN 201
Query: 260 LEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLIC-DRREFNETMQ------EKNIL-- 310
+ E+ LS+ + K E+ + EK++C D + N T Q E +IL
Sbjct: 202 SLRLLYENTEKDLSDTQRHLAKKKYELQLTQEKIMCLDEKIDNFTRQNIAQREEISILGG 261
Query: 311 -LSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKISNQ 369
L+DL+K+ + L++K E + L E L E K I M N ++++ + +
Sbjct: 262 TLNDLAKEKECMQACLDKKSENIASLGESLAMKE----KTISGMKNIIAEMEQASRQCTE 317
Query: 370 --LSCELD--------DESENTYERISLTLDKITNHITYLNTQINETQK---------ND 410
+ CE D DE+ + +I+ D + + L Q + ++ ND
Sbjct: 318 ALIVCEQDVSRMRRQLDETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLND 377
Query: 411 NAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEE 459
L + K+++ D + LK L E+EN++++ + +R +NE+
Sbjct: 378 THNELNDIKQKVQDTNLEVNKLKNILKSEESENRQMM---EQLRKANED 423
Score = 41.1 bits (92), Expect = 0.009
Identities = 65/322 (20%), Positives = 129/322 (40%), Gaps = 23/322 (7%)
Query: 57 DEINSMIRQLXXXXXXXXXXXXXLTEKLTIAETKHNDLKKLYEDSASELEALKRENIQMH 116
DE N + Q+ L E+ A+ ++ L K D+ +EL +K++ +Q
Sbjct: 334 DETNDELAQIARERDILAHDNDNLQEQFAKAKQENQALSKKLNDTHNELNDIKQK-VQDT 392
Query: 117 TSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKN 176
+V + I+ S + E A + K DN ++K +LIT
Sbjct: 393 NLEVNKLKNILKSEESENRQMMEQLRKANEDAENWENKARQSEADNNTLKL---ELITA- 448
Query: 177 ETDINELRNSIKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXX 236
E + N L+ + L ++ A Q++ ++EE+ ++ E + L
Sbjct: 449 EAEGNRLKEKVDSLNREVEQHLNAERSYKSQISTLHKSVVKMEEELQKVQFEKVSALADL 508
Query: 237 XXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEIKEKD-ENFKQEIDMLNEKLIC 295
K + N + ++ +++ E++E + ++ EI++L ++
Sbjct: 509 SSTRELCIKLDSS-----KELLN----RQLVAKDQEIEMRENELDSAHSEIELLRSQMAN 559
Query: 296 DRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENN---SYKLIEN 352
+R +MQ LL K +++ L+EK+ ++ L E L EN + +
Sbjct: 560 ERI----SMQNLEALLVANRDKEYQSQIALQEKESEIQLLKEHLCLAENKMAIQSRDVAQ 615
Query: 353 MFNKVSQIASDFKIS-NQLSCE 373
N V+Q+ +D I+ QL E
Sbjct: 616 FRNVVTQLEADLDITKRQLGTE 637
>BC018647-1|AAH18647.1| 1001|Homo sapiens ring finger protein 40
protein.
Length = 1001
Score = 47.2 bits (107), Expect = 1e-04
Identities = 51/223 (22%), Positives = 105/223 (47%), Gaps = 17/223 (7%)
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEK----DENFKQEIDMLNEKLICDRREFNETMQEK 307
A K A ++E+++ + E + + +E DE+ + I E++ +R+ T QE+
Sbjct: 692 AERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEE 751
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
LLS++ + T + E+ QEQ L++QL + ++ ++KL+ K +QI K+
Sbjct: 752 EALLSEM----DVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERI-KANQI---HKLL 803
Query: 368 NQLSCELDDESENTYERIS---LTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQI 422
+ EL ++ ++ LT+ K+ L + +K +Q L K++
Sbjct: 804 REEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKA 863
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
+ + LK +L ++T +E+ + R + E+ + NLK
Sbjct: 864 VEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLK 906
>BC011769-1|AAH11769.1| 1001|Homo sapiens ring finger protein 40
protein.
Length = 1001
Score = 47.2 bits (107), Expect = 1e-04
Identities = 51/223 (22%), Positives = 105/223 (47%), Gaps = 17/223 (7%)
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEK----DENFKQEIDMLNEKLICDRREFNETMQEK 307
A K A ++E+++ + E + + +E DE+ + I E++ +R+ T QE+
Sbjct: 692 AERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEE 751
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
LLS++ + T + E+ QEQ L++QL + ++ ++KL+ K +QI K+
Sbjct: 752 EALLSEM----DVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERI-KANQI---HKLL 803
Query: 368 NQLSCELDDESENTYERIS---LTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQI 422
+ EL ++ ++ LT+ K+ L + +K +Q L K++
Sbjct: 804 REEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKA 863
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
+ + LK +L ++T +E+ + R + E+ + NLK
Sbjct: 864 VEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLK 906
>BC006133-1|AAH06133.1| 1001|Homo sapiens ring finger protein 40
protein.
Length = 1001
Score = 47.2 bits (107), Expect = 1e-04
Identities = 51/223 (22%), Positives = 105/223 (47%), Gaps = 17/223 (7%)
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEK----DENFKQEIDMLNEKLICDRREFNETMQEK 307
A K A ++E+++ + E + + +E DE+ + I E++ +R+ T QE+
Sbjct: 692 AERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEE 751
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
LLS++ + T + E+ QEQ L++QL + ++ ++KL+ K +QI K+
Sbjct: 752 EALLSEM----DVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERI-KANQI---HKLL 803
Query: 368 NQLSCELDDESENTYERIS---LTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQI 422
+ EL ++ ++ LT+ K+ L + +K +Q L K++
Sbjct: 804 REEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKA 863
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
+ + LK +L ++T +E+ + R + E+ + NLK
Sbjct: 864 VEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLK 906
>AL136382-2|CAI23514.1| 636|Homo sapiens novel protein protein.
Length = 636
Score = 47.2 bits (107), Expect = 1e-04
Identities = 76/372 (20%), Positives = 154/372 (41%), Gaps = 40/372 (10%)
Query: 111 ENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLD 170
E I +++ + I E++ + F+S++ +ALE L+K + ++ ++L
Sbjct: 76 EKINFENANLSALNLKISEQKEILIKELDTFKSVK-LALEHLLRKRDYKQTGDNLSSMLL 134
Query: 171 KLITKNETDINELRNSIKYLES--------VKSE-YNTANEKLFEQLNNAVDKQNCIQEE 221
+ +T NE++ L+ + E+ +SE NT F Q V ++ +Q +
Sbjct: 135 ENLTDNESENTNLKKKVFEKEAHIQELSCLFQSEKANTLKANRFSQSVKVVHER--LQIQ 192
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE---MKTMLVEEKLSEIKEK 278
+ + EN L + ++E KT+ +++ K++
Sbjct: 193 IHKREAENDKLKEYVKSLETKIAKWNLQSRMNKNEAIVMKEASRQKTVALKKASKVYKQR 252
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK-KVNKTERE--LEEKQEQLTHL 335
++F I+ L ++ + +ET+ N S K + KTE E +E ++Q+ +L
Sbjct: 253 LDHFTGAIEKLTSQIRDQEAKLSETISASNAWKSHYEKIVIEKTELEVQIETMKKQIINL 312
Query: 336 MEQLNDTENNSYKLIENMFNKVSQI--------ASDFKISNQLSCELDDESENTYERISL 387
+E L E++ E + KV I + K+ + C + ES+N I L
Sbjct: 313 LEDLKKMEDHGKNSCEEILRKVHSIEYENETLNLENTKLKLRFPCRI-TESKNMNILIVL 371
Query: 388 -----------TLDKITNHITYLNTQINETQKNDNAQ--LLWEAKKQIADLTEQNIILKE 434
TL + + + + +++E Q+ + Q L+ K Q+ L E I+K
Sbjct: 372 DMLCYISSEKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKS 431
Query: 435 RLSQLETENKEL 446
R L +N ++
Sbjct: 432 RCENLLHKNNQI 443
>AL133410-4|CAI10977.1| 284|Homo sapiens tropomyosin 2 (beta)
protein.
Length = 284
Score = 47.2 bits (107), Expect = 1e-04
Identities = 57/301 (18%), Positives = 133/301 (44%), Gaps = 34/301 (11%)
Query: 216 NCIQEEVDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEEMKTMLVEEKLSEI 275
+ I++++ +LK++ +N + A D+ LEE + L ++KL
Sbjct: 2 DAIKKKMQMLKLDKENAIDRAEQAEADKKQ------AEDR-CKQLEEEQQAL-QKKLKGT 53
Query: 276 KEKDENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHL 335
+++ E + + + EKL ++ E T E ++ + L++++ E EL+ QE+L
Sbjct: 54 EDEVEKYSESVKEAQEKL--EQAEKKATDAEADV--ASLNRRIQLVEEELDRAQERLATA 109
Query: 336 MEQLNDTE------NNSYKLIENMFNKVSQIASDFKISNQLSCELDDESENTYERISLTL 389
+++L + E K+IEN K + ++ + + + ++S+ YE
Sbjct: 110 LQKLEEAEKAADESERGMKVIENRAMKDEEKMELQEMQLKEAKHIAEDSDRKYE------ 163
Query: 390 DKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLTEQNIILKERLSQLETENKELLIE 449
++ + L ++ ++ + A++ A+ + DL E+ I+ L LE + + +
Sbjct: 164 -EVARKLVILEGELERSE--ERAEV---AESKCGDLEEELKIVTNNLKSLEAQADKYSTK 217
Query: 450 IQTVRGSNEEVTLNLKDSSTXXXXXXXXXXXXSNEIEDMKTKV----MEWKSQFEDLDDV 505
+ + LK++ T I+D++ +V M++K+ E+LD+
Sbjct: 218 EDKYEEEIKLLEEKLKEAETRAEFAERSVAKLEKTIDDLEDEVYAQKMKYKAISEELDNA 277
Query: 506 M 506
+
Sbjct: 278 L 278
>AC108512-1|AAX82030.1| 684|Homo sapiens unknown protein.
Length = 684
Score = 47.2 bits (107), Expect = 1e-04
Identities = 64/319 (20%), Positives = 132/319 (41%), Gaps = 24/319 (7%)
Query: 127 IDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS 186
I + + +L N + LE ++ + K N+ ++ + + L I+++E I L +
Sbjct: 318 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLL----ISQHEAKIKSLTDY 373
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
++ +E + + + + L E+L ++ EV E ++L +
Sbjct: 374 MQNMEQKRRQLEESQDSLSEELAKLRAQEK--MHEVSFQDKEKEHLTRLQDAEEMKKALE 431
Query: 247 XXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQE 306
R+ L ++ +EEK +I ++ + Q++ + EKL D + QE
Sbjct: 432 QQMESHREAHQKQLSRLRDE-IEEK-QKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQE 489
Query: 307 KNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI 366
+ + L L L +K+EQ ++ L +T + + + N+ K+ D
Sbjct: 490 REMKLEKLLL--------LNDKREQAREDLKGLEETVSRELQTLHNL-RKL--FVQDLTT 538
Query: 367 SNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLT 426
+ S ELD++ + + N++ L T++++ DNA L E K L
Sbjct: 539 RVKKSVELDNDDGGGSAAQKQKISFLENNLEQL-TKVHKQLVRDNADLRCELPK----LE 593
Query: 427 EQNIILKERLSQLETENKE 445
++ ER+ LE+ KE
Sbjct: 594 KRLRATAERVKALESALKE 612
Score = 34.3 bits (75), Expect = 1.1
Identities = 41/214 (19%), Positives = 95/214 (44%), Gaps = 18/214 (8%)
Query: 298 REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV 357
+E N+T+ KN++ L ++N+ +++ +Q N ++ +I+N+ V
Sbjct: 77 KEKNKTL--KNVI-QHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVV 133
Query: 358 SQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
+ I+++ K + D+E + Y ++ D+I N + L ++ + Q D +LL
Sbjct: 134 AGISTEEKE------KYDEEISSLYRQLDDKDDEI-NQQSQLAEKLKQ-QMLDQDELLAS 185
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
++ + E+ L++L+ EN+ E++ V + EE+ +N S
Sbjct: 186 TRRDYEKIQEE-------LTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRA 238
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
++E+ T + + + L ++ Q+K
Sbjct: 239 NEQLTDELAQKTTTLTTTQRELSQLQELSNHQKK 272
>AB033055-1|BAA86543.1| 696|Homo sapiens KIAA1229 protein protein.
Length = 696
Score = 47.2 bits (107), Expect = 1e-04
Identities = 76/372 (20%), Positives = 154/372 (41%), Gaps = 40/372 (10%)
Query: 111 ENIQMHTSDVMVVPEIIDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLD 170
E I +++ + I E++ + F+S++ +ALE L+K + ++ ++L
Sbjct: 136 EKINFENANLSALNLKISEQKEILIKELDTFKSVK-LALEHLLRKRDYKQTGDNLSSMLL 194
Query: 171 KLITKNETDINELRNSIKYLES--------VKSE-YNTANEKLFEQLNNAVDKQNCIQEE 221
+ +T NE++ L+ + E+ +SE NT F Q V ++ +Q +
Sbjct: 195 ENLTDNESENTNLKKKVFEKEAHIQELSCLFQSEKANTLKANRFSQSVKVVHER--LQIQ 252
Query: 222 VDLLKIENQNLLQXXXXXXXXXXXXXXXXXARDKFIANLEE---MKTMLVEEKLSEIKEK 278
+ + EN L + ++E KT+ +++ K++
Sbjct: 253 IHKREAENDKLKEYVKSLETKIAKWNLQSRMNKNEAIVMKEASRQKTVALKKASKVYKQR 312
Query: 279 DENFKQEIDMLNEKLICDRREFNETMQEKNILLSDLSK-KVNKTERE--LEEKQEQLTHL 335
++F I+ L ++ + +ET+ N S K + KTE E +E ++Q+ +L
Sbjct: 313 LDHFTGAIEKLTSQIRDQEAKLSETISASNAWKSHYEKIVIEKTELEVQIETMKKQIINL 372
Query: 336 MEQLNDTENNSYKLIENMFNKVSQI--------ASDFKISNQLSCELDDESENTYERISL 387
+E L E++ E + KV I + K+ + C + ES+N I L
Sbjct: 373 LEDLKKMEDHGKNSCEEILRKVHSIEHENETLNLENTKLKLRFPCRI-TESKNMNILIVL 431
Query: 388 -----------TLDKITNHITYLNTQINETQKNDNAQ--LLWEAKKQIADLTEQNIILKE 434
TL + + + + +++E Q+ + Q L+ K Q+ L E I+K
Sbjct: 432 DMLCYISSEKTTLAALKDEVVSVENELSELQEVEKKQKTLIEMYKTQVQKLQEAAEIVKS 491
Query: 435 RLSQLETENKEL 446
R L +N ++
Sbjct: 492 RCENLLHKNNQI 503
>AB014561-1|BAA31636.2| 1030|Homo sapiens KIAA0661 protein protein.
Length = 1030
Score = 47.2 bits (107), Expect = 1e-04
Identities = 51/223 (22%), Positives = 105/223 (47%), Gaps = 17/223 (7%)
Query: 252 ARDKFIANLEEMKTMLVEEKLSEIKEK----DENFKQEIDMLNEKLICDRREFNETMQEK 307
A K A ++E+++ + E + + +E DE+ + I E++ +R+ T QE+
Sbjct: 721 AERKAKAEVDELRSRIRELEERDRRESKKIADEDALRRIRQAEEQIEHLQRKLGATKQEE 780
Query: 308 NILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKIS 367
LLS++ + T + E+ QEQ L++QL + ++ ++KL+ K +QI K+
Sbjct: 781 EALLSEM----DVTGQAFEDMQEQNGRLLQQLREKDDANFKLMSERI-KANQI---HKLL 832
Query: 368 NQLSCELDDESENTYERIS---LTLDKITNHITYLNTQINETQK--NDNAQLLWEAKKQI 422
+ EL ++ ++ LT+ K+ L + +K +Q L K++
Sbjct: 833 REEKDELGEQVLGLKSQVDAQLLTVQKLEEKERALQGSLGGVEKELTLRSQALELNKRKA 892
Query: 423 ADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLK 465
+ + LK +L ++T +E+ + R + E+ + NLK
Sbjct: 893 VEAAQLAEDLKVQLEHVQTRLREIQPCLAESRAAREKESFNLK 935
>AB011103-1|BAA25457.2| 999|Homo sapiens KIAA0531 protein protein.
Length = 999
Score = 47.2 bits (107), Expect = 1e-04
Identities = 64/319 (20%), Positives = 132/319 (41%), Gaps = 24/319 (7%)
Query: 127 IDSLTEVINTLTNGFESLEEVALEIDLKKNSITKDNISIKTLLDKLITKNETDINELRNS 186
I + + +L N + LE ++ + K N+ ++ + + L I+++E I L +
Sbjct: 633 ISKMKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLL----ISQHEAKIKSLTDY 688
Query: 187 IKYLESVKSEYNTANEKLFEQLNNAVDKQNCIQEEVDLLKIENQNLLQXXXXXXXXXXXX 246
++ +E + + + + L E+L ++ EV E ++L +
Sbjct: 689 MQNMEQKRRQLEESQDSLSEELAKLRAQEK--MHEVSFQDKEKEHLTRLQDAEEMKKALE 746
Query: 247 XXXXXARDKFIANLEEMKTMLVEEKLSEIKEKDENFKQEIDMLNEKLICDRREFNETMQE 306
R+ L ++ +EEK +I ++ + Q++ + EKL D + QE
Sbjct: 747 QQMESHREAHQKQLSRLRDE-IEEK-QKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQE 804
Query: 307 KNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKVSQIASDFKI 366
+ + L L L +K+EQ ++ L +T + + + N+ K+ D
Sbjct: 805 REMKLEKLLL--------LNDKREQAREDLKGLEETVSRELQTLHNL-RKL--FVQDLTT 853
Query: 367 SNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWEAKKQIADLT 426
+ S ELD++ + + N++ L T++++ DNA L E K L
Sbjct: 854 RVKKSVELDNDDGGGSAAQKQKISFLENNLEQL-TKVHKQLVRDNADLRCELPK----LE 908
Query: 427 EQNIILKERLSQLETENKE 445
++ ER+ LE+ KE
Sbjct: 909 KRLRATAERVKALESALKE 927
Score = 34.3 bits (75), Expect = 1.1
Identities = 41/214 (19%), Positives = 95/214 (44%), Gaps = 18/214 (8%)
Query: 298 REFNETMQEKNILLSDLSKKVNKTERELEEKQEQLTHLMEQLNDTENNSYKLIENMFNKV 357
+E N+T+ KN++ L ++N+ +++ +Q N ++ +I+N+ V
Sbjct: 392 KEKNKTL--KNVI-QHLEMELNRWRNGEAVPEDEQISAKDQKNLEPCDNTPIIDNIAPVV 448
Query: 358 SQIASDFKISNQLSCELDDESENTYERISLTLDKITNHITYLNTQINETQKNDNAQLLWE 417
+ I+++ K + D+E + Y ++ D+I N + L ++ + Q D +LL
Sbjct: 449 AGISTEEKE------KYDEEISSLYRQLDDKDDEI-NQQSQLAEKLKQ-QMLDQDELLAS 500
Query: 418 AKKQIADLTEQNIILKERLSQLETENKELLIEIQTVRGSNEEVTLNLKDSSTXXXXXXXX 477
++ + E+ L++L+ EN+ E++ V + EE+ +N S
Sbjct: 501 TRRDYEKIQEE-------LTRLQIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRA 553
Query: 478 XXXXSNEIEDMKTKVMEWKSQFEDLDDVMKQQQK 511
++E+ T + + + L ++ Q+K
Sbjct: 554 NEQLTDELAQKTTTLTTTQRELSQLQELSNHQKK 587
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.308 0.127 0.325
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 54,947,775
Number of Sequences: 224733
Number of extensions: 2048740
Number of successful extensions: 21859
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 295
Number of HSP's successfully gapped in prelim test: 1517
Number of HSP's that attempted gapping in prelim test: 14351
Number of HSP's gapped (non-prelim): 6741
length of query: 517
length of database: 73,234,838
effective HSP length: 93
effective length of query: 424
effective length of database: 52,334,669
effective search space: 22189899656
effective search space used: 22189899656
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.6 bits)
S2: 67 (31.1 bits)
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