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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000850-TA|BGIBMGA000850-PA|IPR001478|PDZ/DHR/GLGF
         (433 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI0000D55C4B Cluster: PREDICTED: similar to CG30483-PA...   220   5e-56
UniRef50_UPI00015B583E Cluster: PREDICTED: similar to GA15871-PA...   202   1e-50
UniRef50_Q7PRJ1 Cluster: ENSANGP00000022135; n=2; Culicidae|Rep:...   158   3e-37
UniRef50_UPI0000DB6DDE Cluster: PREDICTED: similar to Prosap CG3...   117   5e-25
UniRef50_Q292F7 Cluster: GA15871-PA; n=1; Drosophila pseudoobscu...   115   2e-24
UniRef50_A1Z9K8 Cluster: CG30483-PA; n=3; Diptera|Rep: CG30483-P...   113   1e-23
UniRef50_UPI00005A37E0 Cluster: PREDICTED: similar to SH3 and mu...    72   3e-11
UniRef50_Q9UPX8 Cluster: SH3 and multiple ankyrin repeat domains...    72   3e-11
UniRef50_UPI00015A7A57 Cluster: Synaptotagmin-3 (Synaptotagmin I...    71   6e-11
UniRef50_UPI00006A07BC Cluster: Synaptotagmin-3 (Synaptotagmin I...    71   8e-11
UniRef50_UPI0000F3490E Cluster: Synaptotagmin-3 (Synaptotagmin I...    71   8e-11
UniRef50_Q4RWM8 Cluster: Chromosome 3 SCAF14987, whole genome sh...    71   8e-11
UniRef50_Q9Y566 Cluster: SH3 and multiple ankyrin repeat domains...    71   8e-11
UniRef50_Q4T2H5 Cluster: Chromosome undetermined SCAF10273, whol...    70   1e-10
UniRef50_UPI0000EB29EE Cluster: SH3 and multiple ankyrin repeat ...    70   1e-10
UniRef50_Q9BYB0 Cluster: SH3 and multiple ankyrin repeat domains...    70   1e-10
UniRef50_UPI0000584890 Cluster: PREDICTED: similar to SH3 and mu...    69   2e-10
UniRef50_UPI00006A188B Cluster: SH3 and multiple ankyrin repeat ...    69   2e-10
UniRef50_UPI000065D97D Cluster: SH3 and multiple ankyrin repeat ...    69   2e-10
UniRef50_Q1LW87 Cluster: Novel protein similar to vertebrate SH3...    69   2e-10
UniRef50_UPI0000F21E9B Cluster: PREDICTED: hypothetical protein;...    69   3e-10
UniRef50_UPI00015A4C2C Cluster: Synaptotagmin-3 (Synaptotagmin I...    69   3e-10
UniRef50_Q5RGE7 Cluster: Novel protein similar to vertebrate SH3...    69   3e-10
UniRef50_Q675P2 Cluster: SH3 and multiple ankyrin repeat domains...    67   1e-09
UniRef50_A7S0X5 Cluster: Predicted protein; n=1; Nematostella ve...    66   2e-09
UniRef50_UPI0000F21B52 Cluster: PREDICTED: similar to SH3 and mu...    65   3e-09
UniRef50_UPI00015A5E07 Cluster: UPI00015A5E07 related cluster; n...    65   3e-09
UniRef50_Q09493 Cluster: Putative uncharacterized protein shn-1;...    64   9e-09
UniRef50_Q4TAT2 Cluster: Chromosome undetermined SCAF7261, whole...    52   2e-05
UniRef50_Q4S4Q0 Cluster: Chromosome 2 SCAF14738, whole genome sh...    48   6e-04
UniRef50_Q4RJR1 Cluster: Chromosome 13 SCAF15035, whole genome s...    47   0.001
UniRef50_UPI0000F211A9 Cluster: PREDICTED: similar to membrane-a...    43   0.014
UniRef50_Q93566 Cluster: Putative uncharacterized protein; n=2; ...    41   0.055
UniRef50_UPI0000DB7D47 Cluster: PREDICTED: similar to Tyrosine-p...    38   0.68 
UniRef50_A4RVJ8 Cluster: Predicted protein; n=1; Ostreococcus lu...    38   0.68 
UniRef50_Q70Q02 Cluster: PDZ-domain factor 1; n=1; Echinococcus ...    38   0.68 
UniRef50_UPI0000DB6C0C Cluster: PREDICTED: similar to Rhophilin ...    37   0.90 
UniRef50_Q5T2W1 Cluster: PDZ domain-containing protein 1 (CFTR-a...    37   0.90 
UniRef50_UPI000065E2F5 Cluster: Regulator of G-protein signaling...    37   1.2  
UniRef50_UPI000065DD5D Cluster: Homolog of Homo sapiens "protein...    37   1.2  
UniRef50_Q4SQB7 Cluster: Chromosome 4 SCAF14533, whole genome sh...    37   1.2  
UniRef50_A6R1R5 Cluster: Putative uncharacterized protein; n=1; ...    36   1.6  
UniRef50_Q9VRT8 Cluster: CG6619-PA; n=2; Drosophila melanogaster...    36   2.1  
UniRef50_Q13424 Cluster: Alpha-1-syntrophin; n=23; Gnathostomata...    36   2.1  
UniRef50_UPI00015B5174 Cluster: PREDICTED: similar to regulator ...    36   2.7  
UniRef50_UPI00015B4313 Cluster: PREDICTED: similar to rhophilin;...    36   2.7  
UniRef50_UPI0000E4706C Cluster: PREDICTED: similar to beta1-synt...    36   2.7  
UniRef50_Q4S7U1 Cluster: Chromosome 18 SCAF14712, whole genome s...    36   2.7  
UniRef50_Q0VMQ8 Cluster: Peptide synthetase, putative; n=1; Alca...    36   2.7  
UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1; Alca...    36   2.7  
UniRef50_Q9VFD3 Cluster: CG31304-PA; n=6; Diptera|Rep: CG31304-P...    36   2.7  
UniRef50_Q92614 Cluster: Myosin-XVIIIa; n=59; Euteleostomi|Rep: ...    36   2.7  
UniRef50_UPI0001560013 Cluster: PREDICTED: hypothetical protein;...    35   3.6  
UniRef50_UPI0000F1FDA9 Cluster: PREDICTED: hypothetical protein;...    35   3.6  
UniRef50_Q6EHH9 Cluster: Frizzled-8 associated multidomain prote...    35   3.6  
UniRef50_Q4SLD5 Cluster: Chromosome 7 SCAF14557, whole genome sh...    35   3.6  
UniRef50_Q4H4B6 Cluster: Scribble1; n=16; Euteleostomi|Rep: Scri...    35   3.6  
UniRef50_A7SS78 Cluster: Predicted protein; n=3; Nematostella ve...    35   3.6  
UniRef50_Q7SAE8 Cluster: Predicted protein; n=1; Neurospora cras...    35   3.6  
UniRef50_A7E5X2 Cluster: Putative uncharacterized protein; n=1; ...    35   3.6  
UniRef50_P28191 Cluster: Tyrosine-protein phosphatase 1; n=4; Ca...    35   3.6  
UniRef50_Q5JV73 Cluster: FERM and PDZ domain-containing protein ...    35   3.6  
UniRef50_UPI0000DB78FC Cluster: PREDICTED: similar to locomotion...    35   4.8  
UniRef50_UPI0000D577C0 Cluster: PREDICTED: similar to CG31304-PA...    35   4.8  
UniRef50_Q4T9U1 Cluster: Chromosome undetermined SCAF7497, whole...    35   4.8  
UniRef50_Q4ST81 Cluster: Chromosome undetermined SCAF14284, whol...    35   4.8  
UniRef50_Q64512 Cluster: Tyrosine-protein phosphatase non-recept...    35   4.8  
UniRef50_Q12923 Cluster: Tyrosine-protein phosphatase non-recept...    35   4.8  
UniRef50_UPI0000607CB5 Cluster: PREDICTED: similar to two transm...    34   6.3  
UniRef50_A5PKP4 Cluster: LOC100101295 protein; n=1; Xenopus laev...    34   6.3  
UniRef50_Q9ZWA1 Cluster: F11M21.28 protein; n=3; Arabidopsis tha...    34   6.3  
UniRef50_Q9XYY9 Cluster: Rhophilin; n=3; Diptera|Rep: Rhophilin ...    34   6.3  
UniRef50_Q9NDP4 Cluster: Tyrosine phosphatase; n=1; Ciona intest...    34   6.3  
UniRef50_A7RKG0 Cluster: Predicted protein; n=1; Nematostella ve...    34   6.3  
UniRef50_A7RJG2 Cluster: Predicted protein; n=1; Nematostella ve...    34   6.3  
UniRef50_Q8N3D4 Cluster: EH domain-binding protein 1-like protei...    34   6.3  
UniRef50_UPI000065DCC0 Cluster: PDZ domain-containing protein 1 ...    34   8.4  
UniRef50_Q5TTQ8 Cluster: ENSANGP00000025427; n=2; Culicidae|Rep:...    34   8.4  
UniRef50_Q9NY99 Cluster: Gamma-2-syntrophin; n=22; Euteleostomi|...    34   8.4  

>UniRef50_UPI0000D55C4B Cluster: PREDICTED: similar to CG30483-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG30483-PA - Tribolium castaneum
          Length = 1544

 Score =  220 bits (538), Expect = 5e-56
 Identities = 155/310 (50%), Positives = 181/310 (58%), Gaps = 36/310 (11%)

Query: 2   ECRTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGD 61
           E RTVVLHR R+GFGF+LRGAKA+SPLMEL PS++CPALQY                KGD
Sbjct: 531 EPRTVVLHRGRKGFGFILRGAKATSPLMELTPSDKCPALQYLDDVDPGGVADRAGLKKGD 590

Query: 62  FLVAINGEDVSAASHEHVVELIRNSGALXXXXXXXXXXXXXXXXXXACAVPAGKSQSQLP 121
           FL+ IN EDVS+ASHEHVV+LIR SG L                  +  +P     S++P
Sbjct: 591 FLLEINNEDVSSASHEHVVDLIRKSGDLVQMTVMSLAPITTLPMSKSTILPG---PSEVP 647

Query: 122 NSGRPYAATLXXXXXXXXXXXXXXXXXXXXTTLSVGRARAKSMVAGLENGGEKEESCEPL 181
            S R YA TL                    TTLSVGRARAKSMVAGLE G EKEE+ E +
Sbjct: 648 LS-RQYA-TLPRKMGQAPLPPRRDPK----TTLSVGRARAKSMVAGLEIG-EKEET-EDI 699

Query: 182 SAAGKSSSAESVQQPXXXXXXXXXXPRTASVRQRPASSRITAAELEELFQRQAVADAPGG 241
           +   KSSSAES+  P           RTAS+RQRP S+RIT+AELEELFQRQ   D    
Sbjct: 700 A---KSSSAESISTPVQL--------RTASIRQRPTSNRITSAELEELFQRQKTDDK--- 745

Query: 242 NNAMMIRSAFQGGANSPPYSPAKGPGKVYASVAEMKRSRAKLWSK-----CPGTLRREFH 296
           +  +M  S FQ      P SPAK   +VYASVAEMKRS+ K   +       G L R+FH
Sbjct: 746 SKHLMSSSRFQ----DTPSSPAK--TRVYASVAEMKRSKNKSKVRFSTLYSSGELHRDFH 799

Query: 297 STPDLAAELA 306
           STPDLA E+A
Sbjct: 800 STPDLAQEVA 809


>UniRef50_UPI00015B583E Cluster: PREDICTED: similar to GA15871-PA;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           GA15871-PA - Nasonia vitripennis
          Length = 1386

 Score =  202 bits (493), Expect = 1e-50
 Identities = 143/328 (43%), Positives = 167/328 (50%), Gaps = 29/328 (8%)

Query: 2   ECRTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGD 61
           E RTVVLHR+R+GFGFVLRGAK+++ L E+  S R PALQY                KGD
Sbjct: 607 EPRTVVLHRSRKGFGFVLRGAKSTTNLTEVTLSARYPALQYLDDVDEGGVADLAGLRKGD 666

Query: 62  FLVAINGEDVSAASHEHVVELIRNSGALXXXXXXXXXXXXXXXXXXACAVPAGKSQSQLP 121
           FL+ INGEDV+ A HEHVV+LIR SG L                  A    +   Q Q  
Sbjct: 667 FLIQINGEDVTTALHEHVVDLIRKSGELVRMTVVSPVLSLPNSQLAAALPTSQPIQRQYA 726

Query: 122 NSGRPYAATLXXXXXXXXXXXXXXXXXXXXTTLSVGRARAKSMVAGLENGGEKEESCEPL 181
              R    ++                    TTLSVGRARA+SMVAGLE GGEK++  E  
Sbjct: 727 TLPRKTNNSVVIGGTLGRSPAPMPPRRDPKTTLSVGRARARSMVAGLEGGGEKDDRDEMS 786

Query: 182 SAAGKSSSAES--VQQPXX----XXXXXXXXPRTASVRQRPASSRITAAELEELFQRQAV 235
           S   KS+S+ES  + QP              PRTAS+R RP SSRITAAELEELFQRQ  
Sbjct: 787 SNCAKSNSSESLHLNQPTTPGGNANQNSSSQPRTASIRSRPTSSRITAAELEELFQRQQG 846

Query: 236 ADAP-------------GGNNAMMIRSAFQGG---ANSPPYSPAKGPGKVYASVAEMKR- 278
           A+               G    M   S F  G     S   SPAK  G+VYASVAEMKR 
Sbjct: 847 ANGAASSMSSAMSPSHYGSTMQMNSSSHFPSGTISTKSHSTSPAKS-GRVYASVAEMKRK 905

Query: 279 ---SRAKLWSKCPG--TLRREFHSTPDL 301
              SR + +    G   L R+FHSTPDL
Sbjct: 906 GKSSRVRFFGGLGGGSELHRDFHSTPDL 933


>UniRef50_Q7PRJ1 Cluster: ENSANGP00000022135; n=2; Culicidae|Rep:
           ENSANGP00000022135 - Anopheles gambiae str. PEST
          Length = 1238

 Score =  158 bits (383), Expect = 3e-37
 Identities = 122/328 (37%), Positives = 148/328 (45%), Gaps = 31/328 (9%)

Query: 2   ECRTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGD 61
           E RTVVLHRA+RGFGF+LRGAKASSPLM+L+PS RCPALQY                 GD
Sbjct: 557 EPRTVVLHRAKRGFGFILRGAKASSPLMQLKPSPRCPALQYLDDVDPGGVADIAGLKPGD 616

Query: 62  FLVAINGEDVSAASHEHVVELIRNSGALXXXXXXXXXXXXXXXXXXACAVPAGKSQSQLP 121
           FL+AIN EDV+ ASHEHVV+LIRNSG+L                    A   G   S   
Sbjct: 617 FLLAINSEDVTCASHEHVVDLIRNSGSLVSMTVVTLSQNLINSMMLE-ASEIGSQHSSGS 675

Query: 122 NSGRPYAATLXXXXXXXXXXXXXXXXXXXXTTLSVGRARAKSMVAGLENGGEKEESCEPL 181
               P ++                        +   R    ++  G           E  
Sbjct: 676 GMSTPISSRQCSTLPRRMNSGPPGSNCKQPAPMPPRRDPKTTLSVGRARAKSMVAGLEGG 735

Query: 182 SAAGKSSSAESVQQPXXXXXXXXXXPRTASVRQRPAS--SRIT-----AAELEELFQRQA 234
               ++   ++ QQ                V+ R AS  SR T     AAELEELFQRQ 
Sbjct: 736 GEKAQTQLLQAQQQCHSAIGTPTQTGPGTPVQPRTASIKSRPTSSRITAAELEELFQRQQ 795

Query: 235 VADAPGGNNAMMIRSA-------FQGGANSPPYSPAKGPGKVYASVAEMKRSRAKLWS-- 285
            ADA   N   M+ S+       F  GA +PP SP KGP  VYASVAEMKR ++      
Sbjct: 796 GADA---NRCSMLMSSSRFQSTGFDSGAGTPPISPQKGP-IVYASVAEMKRKKSSKVGMG 851

Query: 286 ----------KCPGTLRREFHSTPDLAA 303
                     +    L+R FHSTPDLA+
Sbjct: 852 TLKGRPIPIPQVGSDLKRTFHSTPDLAS 879


>UniRef50_UPI0000DB6DDE Cluster: PREDICTED: similar to Prosap
           CG30483-PA; n=1; Apis mellifera|Rep: PREDICTED: similar
           to Prosap CG30483-PA - Apis mellifera
          Length = 1393

 Score =  117 bits (282), Expect = 5e-25
 Identities = 62/124 (50%), Positives = 74/124 (59%), Gaps = 2/124 (1%)

Query: 2   ECRTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGD 61
           E RTVVLHR+R+GFGFVLRGAKA+SPLMEL PS R PALQY                KGD
Sbjct: 683 EPRTVVLHRSRKGFGFVLRGAKATSPLMELTPSARYPALQYLDDVDQGGVADLAGLRKGD 742

Query: 62  FLVAINGEDVSAASHEHVVELIRNSGALXXXXXXXXXXXXXXXXXXACAVPAGKSQSQLP 121
           +L+ INGEDV+ ASHEHVV+LIR SG L                  +  +P  +  S  P
Sbjct: 743 YLIQINGEDVTTASHEHVVDLIRKSGELRDDRDEITSTGAKSSSAESIHLP--QQPSTGP 800

Query: 122 NSGR 125
           N+G+
Sbjct: 801 NTGQ 804



 Score =  105 bits (253), Expect = 2e-21
 Identities = 81/183 (44%), Positives = 102/183 (55%), Gaps = 21/183 (11%)

Query: 156 VGRARAKSMVAGLENGGEKEESCEPLSAAG-KSSSAESV---QQPXXXXXXXXXXP---R 208
           V  A  + +V  +   GE  +  + +++ G KSSSAES+   QQP          P   R
Sbjct: 752 VTTASHEHVVDLIRKSGELRDDRDEITSTGAKSSSAESIHLPQQPSTGPNTGQNTPVQPR 811

Query: 209 TASVRQRPASSRITAAELEELFQRQAVADAPGGNNAMMIRSAFQGG--ANSPPYSPAKGP 266
           TAS+R RP SSRITAAELEELFQRQ    A G  ++ M+ S FQ G    S P SPAK  
Sbjct: 812 TASIRSRPTSSRITAAELEELFQRQQ-GSASGQYSSSMMSSHFQTGQATKSHPSSPAK-T 869

Query: 267 GKVYASVAEMKR-----SRAKLWSKCPG--TLRREFHSTPDLAAELAPH---PPRTRSTD 316
           G+VYASVAEMKR     SR + +    G   L R+FHSTPDL  ++      P   RS +
Sbjct: 870 GRVYASVAEMKRKGKLNSRVRFFGGLGGGSDLHRDFHSTPDLNVQVQSSILAPKGHRSQE 929

Query: 317 DVH 319
           DV+
Sbjct: 930 DVN 932


>UniRef50_Q292F7 Cluster: GA15871-PA; n=1; Drosophila
           pseudoobscura|Rep: GA15871-PA - Drosophila pseudoobscura
           (Fruit fly)
          Length = 1643

 Score =  115 bits (277), Expect = 2e-24
 Identities = 57/86 (66%), Positives = 65/86 (75%)

Query: 4   RTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFL 63
           R+VVLHRA+RGFGF+LRGAKASS LM+LRPSER PALQY                 GDFL
Sbjct: 634 RSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFL 693

Query: 64  VAINGEDVSAASHEHVVELIRNSGAL 89
           + INGEDVSAASHE VVE+IR++GAL
Sbjct: 694 LTINGEDVSAASHEQVVEMIRSAGAL 719



 Score = 99.5 bits (237), Expect = 1e-19
 Identities = 73/154 (47%), Positives = 83/154 (53%), Gaps = 24/154 (15%)

Query: 152 TTLSVGRARAKSMVAGLENGGEKEESCEPLSAAGKSSSAESVQQPXXXX------XXXXX 205
           TTLSVGRARAKSMVAGLENGGEKE+  +   +    S A S+                  
Sbjct: 805 TTLSVGRARAKSMVAGLENGGEKEDDVQHTKSNSVESIATSIAASVATSNGNGNGNNNQT 864

Query: 206 XP------RTASVRQRPASSRITAAELEELFQRQAVADAPGGNNA----MMIRSAFQGGA 255
            P      RTAS++ RP SSRITAAELEELFQRQ   D    N +    MM  S FQ G 
Sbjct: 865 GPGTPVQLRTASIKARPTSSRITAAELEELFQRQQ-GDGSAANASRYATMMTSSRFQSGT 923

Query: 256 NS----PPY---SPAKGPGKVYASVAEMKRSRAK 282
           +S    PP    SP +    VY SVAEMKR  A+
Sbjct: 924 DSGAATPPATNGSPMRSGPLVYGSVAEMKRKTAR 957


>UniRef50_A1Z9K8 Cluster: CG30483-PA; n=3; Diptera|Rep: CG30483-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 1843

 Score =  113 bits (271), Expect = 1e-23
 Identities = 55/86 (63%), Positives = 65/86 (75%)

Query: 4   RTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFL 63
           R+VVLHRA+RGFGF+LRGAKASS LM+LRPSER PALQY                 GDFL
Sbjct: 679 RSVVLHRAKRGFGFILRGAKASSQLMQLRPSERFPALQYLDDVDPGGVADMAGLRPGDFL 738

Query: 64  VAINGEDVSAASHEHVVELIRNSGAL 89
           + INGEDV++ASHE VVE+IR++GAL
Sbjct: 739 LTINGEDVTSASHEQVVEMIRSAGAL 764



 Score =  109 bits (263), Expect = 1e-22
 Identities = 86/185 (46%), Positives = 100/185 (54%), Gaps = 22/185 (11%)

Query: 152  TTLSVGRARAKSMVAGLENGGEKEESCEPLSAAGKSSSAESVQQPX-XXXXXXXXXP--- 207
            TTLSVGRARAKSMVAGLENGGEKE+         KS+S ES+  P           P   
Sbjct: 846  TTLSVGRARAKSMVAGLENGGEKEDDLPHT----KSNSVESIATPTPTGIQTGPGTPVQL 901

Query: 208  RTASVRQRPASSRITAAELEELFQRQAVADAPGGNN---AMMIRSAFQGGANS----PPY 260
            RTAS++ RP SSRITAAELEELFQRQ    +    +    MM  S FQ G +S    PP 
Sbjct: 902  RTASIKARPTSSRITAAELEELFQRQQGEGSAANASRYATMMTSSRFQSGTDSGAATPPA 961

Query: 261  ---SPAKGPGKVYASVAEMKRSRAKLWSKCPGTLRREFHSTPDL---AAELAPHPPRTRS 314
               SP +    VY SVAEMKR  A+      GTLR +  +TP +    A       R  S
Sbjct: 962  SNGSPMRSGPLVYGSVAEMKRKTARS-KHGSGTLRGKPVATPTVGPGGAGGGRDLKRFHS 1020

Query: 315  TDDVH 319
            T D+H
Sbjct: 1021 TPDLH 1025


>UniRef50_UPI00005A37E0 Cluster: PREDICTED: similar to SH3 and
           multiple ankyrin repeat domains 2 isoform 1; n=1; Canis
           lupus familiaris|Rep: PREDICTED: similar to SH3 and
           multiple ankyrin repeat domains 2 isoform 1 - Canis
           familiaris
          Length = 1938

 Score = 71.7 bits (168), Expect = 3e-11
 Identities = 37/88 (42%), Positives = 47/88 (53%), Gaps = 1/88 (1%)

Query: 1   MECRTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXK 59
           +E +TVVL +    GFGFVLRGAKA +P+ E  P+   PALQY                 
Sbjct: 618 IEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRT 677

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSG 87
           GDFL+ +N E+V    H  VV +IR  G
Sbjct: 678 GDFLIEVNNENVVKVGHRQVVNMIRQGG 705


>UniRef50_Q9UPX8 Cluster: SH3 and multiple ankyrin repeat domains
           protein 2; n=46; Euteleostomi|Rep: SH3 and multiple
           ankyrin repeat domains protein 2 - Homo sapiens (Human)
          Length = 1253

 Score = 71.7 bits (168), Expect = 3e-11
 Identities = 37/88 (42%), Positives = 47/88 (53%), Gaps = 1/88 (1%)

Query: 1   MECRTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXK 59
           +E +TVVL +    GFGFVLRGAKA +P+ E  P+   PALQY                 
Sbjct: 33  IEEKTVVLQKKDNEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRT 92

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSG 87
           GDFL+ +N E+V    H  VV +IR  G
Sbjct: 93  GDFLIEVNNENVVKVGHRQVVNMIRQGG 120



 Score = 33.9 bits (74), Expect = 8.4
 Identities = 23/78 (29%), Positives = 44/78 (56%), Gaps = 11/78 (14%)

Query: 160 RAKSMVAGLENGGEKEESCEPLSAAGKSSSAESVQQPXXXXXXXXXXPRTASVRQRPASS 219
           R+KSM + LE   +K++  E + A+  S +AE++             PR A+++QRP+S 
Sbjct: 159 RSKSMTSELEELVDKDKPEEIVPASKPSRAAENM----------AVEPRVATIKQRPSSR 208

Query: 220 RITA-AELEELFQRQAVA 236
              A +++  +++RQ +A
Sbjct: 209 CFPAGSDMNSVYERQGIA 226


>UniRef50_UPI00015A7A57 Cluster: Synaptotagmin-3 (Synaptotagmin III)
           (SytIII).; n=1; Danio rerio|Rep: Synaptotagmin-3
           (Synaptotagmin III) (SytIII). - Danio rerio
          Length = 1305

 Score = 70.9 bits (166), Expect = 6e-11
 Identities = 35/85 (41%), Positives = 46/85 (54%), Gaps = 1/85 (1%)

Query: 4   RTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDF 62
           +TV+L +    GFGFVLRGAKA +P+ E  P+   PALQY                 GDF
Sbjct: 111 KTVLLQKKDNEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDF 170

Query: 63  LVAINGEDVSAASHEHVVELIRNSG 87
           L+ +NG++V    H  VV +IR  G
Sbjct: 171 LIEVNGQNVVKVGHRQVVNMIRQGG 195


>UniRef50_UPI00006A07BC Cluster: Synaptotagmin-3 (Synaptotagmin III)
           (SytIII).; n=4; Xenopus tropicalis|Rep: Synaptotagmin-3
           (Synaptotagmin III) (SytIII). - Xenopus tropicalis
          Length = 1677

 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 35/85 (41%), Positives = 46/85 (54%), Gaps = 1/85 (1%)

Query: 4   RTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDF 62
           +TV+L +    GFGFVLRGAKA +P+ E  P+   PALQY                 GDF
Sbjct: 557 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDF 616

Query: 63  LVAINGEDVSAASHEHVVELIRNSG 87
           L+ +NG++V    H  VV +IR  G
Sbjct: 617 LIEVNGQNVVKVGHRQVVNMIRQGG 641


>UniRef50_UPI0000F3490E Cluster: Synaptotagmin-3 (Synaptotagmin
          III) (SytIII).; n=1; Bos taurus|Rep: Synaptotagmin-3
          (Synaptotagmin III) (SytIII). - Bos Taurus
          Length = 1265

 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 35/85 (41%), Positives = 46/85 (54%), Gaps = 1/85 (1%)

Query: 4  RTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDF 62
          +TV+L +    GFGFVLRGAKA +P+ E  P+   PALQY                 GDF
Sbjct: 8  KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDF 67

Query: 63 LVAINGEDVSAASHEHVVELIRNSG 87
          L+ +NG++V    H  VV +IR  G
Sbjct: 68 LIEVNGQNVVKVGHRQVVNMIRQGG 92


>UniRef50_Q4RWM8 Cluster: Chromosome 3 SCAF14987, whole genome
           shotgun sequence; n=8; Euteleostomi|Rep: Chromosome 3
           SCAF14987, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 2229

 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 35/85 (41%), Positives = 46/85 (54%), Gaps = 1/85 (1%)

Query: 4   RTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDF 62
           +TV+L +    GFGFVLRGAKA +P+ E  P+   PALQY                 GDF
Sbjct: 594 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDF 653

Query: 63  LVAINGEDVSAASHEHVVELIRNSG 87
           L+ +NG++V    H  VV +IR  G
Sbjct: 654 LIEVNGQNVVKVGHRQVVNMIRQGG 678


>UniRef50_Q9Y566 Cluster: SH3 and multiple ankyrin repeat domains
           protein 1; n=18; Eutheria|Rep: SH3 and multiple ankyrin
           repeat domains protein 1 - Homo sapiens (Human)
          Length = 2161

 Score = 70.5 bits (165), Expect = 8e-11
 Identities = 35/85 (41%), Positives = 46/85 (54%), Gaps = 1/85 (1%)

Query: 4   RTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDF 62
           +TV+L +    GFGFVLRGAKA +P+ E  P+   PALQY                 GDF
Sbjct: 662 KTVLLQKKDSEGFGFVLRGAKAQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDF 721

Query: 63  LVAINGEDVSAASHEHVVELIRNSG 87
           L+ +NG++V    H  VV +IR  G
Sbjct: 722 LIEVNGQNVVKVGHRQVVNMIRQGG 746


>UniRef50_Q4T2H5 Cluster: Chromosome undetermined SCAF10273, whole
           genome shotgun sequence; n=2; Tetraodontidae|Rep:
           Chromosome undetermined SCAF10273, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 1363

 Score = 70.1 bits (164), Expect = 1e-10
 Identities = 36/85 (42%), Positives = 45/85 (52%), Gaps = 1/85 (1%)

Query: 4   RTVVLHRARR-GFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDF 62
           +TVVL +    GFGFVLRGAKA +P+ E  P+   PALQY                 GDF
Sbjct: 37  KTVVLQKKENEGFGFVLRGAKADTPIEEFTPTPAFPALQYLESVDEGGVAWQAGLRTGDF 96

Query: 63  LVAINGEDVSAASHEHVVELIRNSG 87
           L+ +N E+V    H  VV +IR  G
Sbjct: 97  LIEVNQENVVKVGHRQVVNMIRQGG 121


>UniRef50_UPI0000EB29EE Cluster: SH3 and multiple ankyrin repeat
           domains protein 3 (Shank3) (Proline- rich
           synapse-associated protein 2) (ProSAP2); n=1; Canis
           lupus familiaris|Rep: SH3 and multiple ankyrin repeat
           domains protein 3 (Shank3) (Proline- rich
           synapse-associated protein 2) (ProSAP2) - Canis
           familiaris
          Length = 1861

 Score = 69.7 bits (163), Expect = 1e-10
 Identities = 35/82 (42%), Positives = 43/82 (52%)

Query: 6   VVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFLVA 65
           V+  R   GFGFVLRGAKA +P+ E  P+   PALQY                 GDFL+ 
Sbjct: 490 VLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIE 549

Query: 66  INGEDVSAASHEHVVELIRNSG 87
           +NG +V    H+ VV LIR  G
Sbjct: 550 VNGVNVVKVGHKQVVALIRQGG 571


>UniRef50_Q9BYB0 Cluster: SH3 and multiple ankyrin repeat domains
           protein 3; n=23; Mammalia|Rep: SH3 and multiple ankyrin
           repeat domains protein 3 - Homo sapiens (Human)
          Length = 1741

 Score = 69.7 bits (163), Expect = 1e-10
 Identities = 35/82 (42%), Positives = 43/82 (52%)

Query: 6   VVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFLVA 65
           V+  R   GFGFVLRGAKA +P+ E  P+   PALQY                 GDFL+ 
Sbjct: 574 VLQKRDHEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIE 633

Query: 66  INGEDVSAASHEHVVELIRNSG 87
           +NG +V    H+ VV LIR  G
Sbjct: 634 VNGVNVVKVGHKQVVALIRQGG 655



 Score = 39.9 bits (89), Expect = 0.13
 Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 9/85 (10%)

Query: 152 TTLSVGRARAKSMVAGLEN-GGEKEESCEPLSAAGKSSSAESVQQPXXXXXXXXXXPRTA 210
           TTL++   R+KSM A LE     +    E L     +++AE   +P           R A
Sbjct: 688 TTLTL---RSKSMTAELEELASIRRRKGEKLDEM-LAAAAEPTLRPDIADADS----RAA 739

Query: 211 SVRQRPASSRITAAELEELFQRQAV 235
           +V+QRP S RIT AE+  LF+RQ +
Sbjct: 740 TVKQRPTSRRITPAEISSLFERQGL 764


>UniRef50_UPI0000584890 Cluster: PREDICTED: similar to SH3 and
           multiple ankyrin repeat domains protein 2 (Shank2)
           (Proline-rich synapse-associated protein 1) (ProSAP1)
           (Cortactin-binding protein 1) (CortBP1)
           (GKAP/SAPAP-interacting protein) (SPANK-3); n=2;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           SH3 and multiple ankyrin repeat domains protein 2
           (Shank2) (Proline-rich synapse-associated protein 1)
           (ProSAP1) (Cortactin-binding protein 1) (CortBP1)
           (GKAP/SAPAP-interacting protein) (SPANK-3) -
           Strongylocentrotus purpuratus
          Length = 1038

 Score = 69.3 bits (162), Expect = 2e-10
 Identities = 62/244 (25%), Positives = 98/244 (40%), Gaps = 14/244 (5%)

Query: 4   RTVVLHRARRGFGFVLRGAKA-SSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDF 62
           R   + R ++GFGFVLRGAK+     +   P++  PALQY                 GDF
Sbjct: 129 RIACVQRGKKGFGFVLRGAKSPQGGAVSFTPTKDFPALQYLEHVDKGSPGDKAGLKMGDF 188

Query: 63  LVAINGEDVSAASHEHVVELIRNS-GALXXXXXXXXXXXXXXXXXXACAVPAGKSQSQLP 121
           ++ INGEDVS+A H++VV L+ +S   +                     +    +   LP
Sbjct: 189 ILEINGEDVSSAPHQYVVNLVVSSPDTIVIKIITVPNSKAYSWLKEGGTLRRSGNGPHLP 248

Query: 122 NSGRPYAATLXXXXXXXXXXXXXXXXXXXXTTLSVGRARAKSMVAGLENGGEKEESCEPL 181
            S  P A                       TT S+  +  +       +      S  P 
Sbjct: 249 IS-TP-ATKSIAISSQDQNSNSPSIPVSTPTTRSISISSQEQHAVDELDKAIDSASTTPK 306

Query: 182 SAAGKSSSAESVQQPXXXXXXXXXXPRTASVRQRPASSRITAAELEELFQRQAVADAPGG 241
             +  SS   S+Q+           P+TAS+R+RP   +++  +L+ +FQRQ  + +   
Sbjct: 307 YVSPASSRCSSIQE---------DEPKTASIRKRPI-RQVSQQQLKGIFQRQGSSSSETN 356

Query: 242 NNAM 245
            N+M
Sbjct: 357 LNSM 360


>UniRef50_UPI00006A188B Cluster: SH3 and multiple ankyrin repeat
           domains protein 3 (Shank3) (Proline- rich
           synapse-associated protein 2) (ProSAP2); n=6; Xenopus
           tropicalis|Rep: SH3 and multiple ankyrin repeat domains
           protein 3 (Shank3) (Proline- rich synapse-associated
           protein 2) (ProSAP2) - Xenopus tropicalis
          Length = 1740

 Score = 69.3 bits (162), Expect = 2e-10
 Identities = 34/79 (43%), Positives = 42/79 (53%)

Query: 10  RARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFLVAINGE 69
           R   GFGFVLRGAKA +P+ E  P+   PALQY                 GDFL+ +NG 
Sbjct: 628 RELEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVDGVAWRAGLRTGDFLIEVNGV 687

Query: 70  DVSAASHEHVVELIRNSGA 88
           +V    H+ VV LIR  G+
Sbjct: 688 NVVKVGHKQVVSLIRQGGS 706



 Score = 35.9 bits (79), Expect = 2.1
 Identities = 15/28 (53%), Positives = 20/28 (71%)

Query: 208 RTASVRQRPASSRITAAELEELFQRQAV 235
           R A+V+QRP S RIT AE+  L +RQ +
Sbjct: 779 RAATVKQRPTSRRITPAEISSLLERQGI 806


>UniRef50_UPI000065D97D Cluster: SH3 and multiple ankyrin repeat
           domains protein 3 (Shank3) (Proline- rich
           synapse-associated protein 2) (ProSAP2); n=1; Takifugu
           rubripes|Rep: SH3 and multiple ankyrin repeat domains
           protein 3 (Shank3) (Proline- rich synapse-associated
           protein 2) (ProSAP2) - Takifugu rubripes
          Length = 1859

 Score = 69.3 bits (162), Expect = 2e-10
 Identities = 35/86 (40%), Positives = 44/86 (51%)

Query: 2   ECRTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGD 61
           E   V+  +   GFGFVLRGAKA +P+ E  P+   PALQY                 GD
Sbjct: 538 EKNAVLQKKESEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGD 597

Query: 62  FLVAINGEDVSAASHEHVVELIRNSG 87
           FL+ +NG +V    H+ VV LIR  G
Sbjct: 598 FLIEVNGVNVIKLGHKQVVSLIRQGG 623



 Score = 38.3 bits (85), Expect = 0.39
 Identities = 35/84 (41%), Positives = 45/84 (53%), Gaps = 16/84 (19%)

Query: 152 TTLSVGRARAKSMVAGLENGGEKEESCEPLSAAGKSSSAESVQQPXXXXXXXXXXPRTAS 211
           TTL++   R+KSM A LE   E E   E L  A + S+  S  QP           R A+
Sbjct: 725 TTLTL---RSKSMTAELE---ELERLDEML--ASQESALRS--QPSEADY------RAAT 768

Query: 212 VRQRPASSRITAAELEELFQRQAV 235
           V+QRP S RIT AE+  LF+RQ +
Sbjct: 769 VKQRPTSRRITPAEISSLFERQGM 792


>UniRef50_Q1LW87 Cluster: Novel protein similar to vertebrate SH3
           and multiple ankyrin repeat domains 2; n=5; Danio
           rerio|Rep: Novel protein similar to vertebrate SH3 and
           multiple ankyrin repeat domains 2 - Danio rerio
           (Zebrafish) (Brachydanio rerio)
          Length = 1466

 Score = 68.9 bits (161), Expect = 2e-10
 Identities = 34/86 (39%), Positives = 44/86 (51%)

Query: 2   ECRTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGD 61
           E   ++  +   GFGFVLRGAKA +P+ E  P+   PALQY                 GD
Sbjct: 245 EKNAMLQKKENEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGD 304

Query: 62  FLVAINGEDVSAASHEHVVELIRNSG 87
           FL+ +NG +V    H+ VV LIR  G
Sbjct: 305 FLIEVNGVNVVKVGHKQVVSLIRQGG 330



 Score = 39.5 bits (88), Expect = 0.17
 Identities = 35/85 (41%), Positives = 46/85 (54%), Gaps = 17/85 (20%)

Query: 152 TTLSVGRARAKSMVAGLENGGEKEESCEPLSAAGKSSSAESVQQPXXXXXXXXXXPRTAS 211
           TTL++   R+KSM A LE   E E   E L+      S E+V +P           R A+
Sbjct: 364 TTLTL---RSKSMTAELE---ELERLDEILA------SQETVLRPKVEADY-----RAAT 406

Query: 212 VRQRPASSRITAAELEELFQRQAVA 236
           V+QRP S RIT AE+  LF+RQ +A
Sbjct: 407 VKQRPTSRRITPAEISSLFERQGLA 431


>UniRef50_UPI0000F21E9B Cluster: PREDICTED: hypothetical protein;
           n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 2302

 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 35/85 (41%), Positives = 45/85 (52%), Gaps = 1/85 (1%)

Query: 4   RTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDF 62
           +TV+L +    GFGFVLRGAKA +P+ E  P+   PALQY                 GDF
Sbjct: 730 KTVLLQKKDNEGFGFVLRGAKAQTPVEEFSPTPAFPALQYLESVDEGGVAWRSGLRMGDF 789

Query: 63  LVAINGEDVSAASHEHVVELIRNSG 87
           L+ +NG +V    H  VV +IR  G
Sbjct: 790 LIEVNGINVVKVGHRQVVNMIRQGG 814


>UniRef50_UPI00015A4C2C Cluster: Synaptotagmin-3 (Synaptotagmin III)
           (SytIII).; n=1; Danio rerio|Rep: Synaptotagmin-3
           (Synaptotagmin III) (SytIII). - Danio rerio
          Length = 1302

 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 35/85 (41%), Positives = 45/85 (52%), Gaps = 1/85 (1%)

Query: 4   RTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDF 62
           +TV+L +    GFGFVLRGAKA +P+ E  P+   PALQY                 GDF
Sbjct: 113 KTVLLQKKDNEGFGFVLRGAKAQTPVEEFSPTPAFPALQYLESVDEGGVAWRSGLRMGDF 172

Query: 63  LVAINGEDVSAASHEHVVELIRNSG 87
           L+ +NG +V    H  VV +IR  G
Sbjct: 173 LIEVNGINVVKVGHRQVVNMIRQGG 197


>UniRef50_Q5RGE7 Cluster: Novel protein similar to vertebrate SH3
           and multiple ankyrin repeat domains family protein; n=5;
           Euteleostomi|Rep: Novel protein similar to vertebrate
           SH3 and multiple ankyrin repeat domains family protein -
           Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 1601

 Score = 68.5 bits (160), Expect = 3e-10
 Identities = 34/79 (43%), Positives = 40/79 (50%)

Query: 10  RARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFLVAINGE 69
           R   GFGFVLRGAKA +P+ E  P+   PALQY                 GDFL+ +NG 
Sbjct: 575 RDSEGFGFVLRGAKAETPIEEFTPTPAFPALQYLESVDLEGVAWRAGLRTGDFLIEVNGV 634

Query: 70  DVSAASHEHVVELIRNSGA 88
            V    H  VV LIR  G+
Sbjct: 635 SVVKVGHRQVVSLIRQGGS 653



 Score = 38.3 bits (85), Expect = 0.39
 Identities = 26/76 (34%), Positives = 35/76 (46%), Gaps = 3/76 (3%)

Query: 160 RAKSMVAGLENGGEKEESCEPLSAAGKSSSAESVQQPXXXXXXXXXXPRTASVRQRPASS 219
           R+KSM A LE    +    E L    +  S+   Q             R A+V+QRP S 
Sbjct: 691 RSKSMTAELEELASRRRRGEKLD---EMLSSPKEQVVVMRQRPVDSDSRAATVKQRPTSR 747

Query: 220 RITAAELEELFQRQAV 235
           RIT AE+  L +RQ +
Sbjct: 748 RITQAEISSLLERQGL 763


>UniRef50_Q675P2 Cluster: SH3 and multiple ankyrin repeat domains
          3-like protein; n=1; Oikopleura dioica|Rep: SH3 and
          multiple ankyrin repeat domains 3-like protein -
          Oikopleura dioica (Tunicate)
          Length = 589

 Score = 66.9 bits (156), Expect = 1e-09
 Identities = 34/83 (40%), Positives = 41/83 (49%)

Query: 4  RTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFL 63
          R V L R   GFGFVLRGAK   P+ E  PS   PA+QY                 GDF+
Sbjct: 11 RRVELARGANGFGFVLRGAKNDGPIAEFTPSPAFPAVQYLESVDPNGPAHEAGLRDGDFI 70

Query: 64 VAINGEDVSAASHEHVVELIRNS 86
          + ING  +  A H   V+LIR +
Sbjct: 71 IEINGISIIRAGHRQAVDLIRGA 93


>UniRef50_A7S0X5 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 638

 Score = 66.1 bits (154), Expect = 2e-09
 Identities = 33/82 (40%), Positives = 47/82 (57%), Gaps = 1/82 (1%)

Query: 4   RTVVLHRARRG-FGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDF 62
           R V L+R  +G FGF +RGA + +P ++ +P+   PALQY                  DF
Sbjct: 556 RVVTLYRGNQGGFGFQMRGANSQTPRLDFQPTLEFPALQYIGEVERGGEADRKGVKCKDF 615

Query: 63  LVAINGEDVSAASHEHVVELIR 84
           ++ +N EDV+ A+H HVVELIR
Sbjct: 616 ILEVNWEDVTTATHTHVVELIR 637


>UniRef50_UPI0000F21B52 Cluster: PREDICTED: similar to SH3 and
           multiple ankyrin repeat domains 2; n=2; Danio rerio|Rep:
           PREDICTED: similar to SH3 and multiple ankyrin repeat
           domains 2 - Danio rerio
          Length = 1105

 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 35/87 (40%), Positives = 45/87 (51%), Gaps = 1/87 (1%)

Query: 2   ECRTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKG 60
           E +TVVL +    GFGFVLRGAKA +P+ E  P+   PALQY                 G
Sbjct: 19  EQKTVVLQKQDSEGFGFVLRGAKADTPIEEFIPTAAFPALQYLESVDEGGVAWLMGLRTG 78

Query: 61  DFLVAINGEDVSAASHEHVVELIRNSG 87
           DFL  +N + V    H  VV +I++ G
Sbjct: 79  DFLTEVNHQSVVKMGHRQVVSMIKHGG 105


>UniRef50_UPI00015A5E07 Cluster: UPI00015A5E07 related cluster; n=1;
           Danio rerio|Rep: UPI00015A5E07 UniRef100 entry - Danio
           rerio
          Length = 1081

 Score = 65.3 bits (152), Expect = 3e-09
 Identities = 35/87 (40%), Positives = 45/87 (51%), Gaps = 1/87 (1%)

Query: 2   ECRTVVLHRA-RRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKG 60
           E +TVVL +    GFGFVLRGAKA +P+ E  P+   PALQY                 G
Sbjct: 33  EQKTVVLQKQDSEGFGFVLRGAKADTPIEEFIPTAAFPALQYLESVDEGGVAWLMGLRTG 92

Query: 61  DFLVAINGEDVSAASHEHVVELIRNSG 87
           DFL  +N + V    H  VV +I++ G
Sbjct: 93  DFLTEVNHQSVVKMGHRQVVSMIKHGG 119


>UniRef50_Q09493 Cluster: Putative uncharacterized protein shn-1;
           n=3; Caenorhabditis|Rep: Putative uncharacterized
           protein shn-1 - Caenorhabditis elegans
          Length = 1110

 Score = 63.7 bits (148), Expect = 9e-09
 Identities = 31/84 (36%), Positives = 46/84 (54%)

Query: 4   RTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFL 63
           R +V+ R  +GFGF+LRGAK  +  +   P+ + PALQ+                 GD+L
Sbjct: 435 RILVIPRGVKGFGFILRGAKHVAMPLNFEPTAQVPALQFFEGVDMSGMAVRAGLRPGDYL 494

Query: 64  VAINGEDVSAASHEHVVELIRNSG 87
           + I+G DV   SH+ VVE I+ +G
Sbjct: 495 LEIDGIDVRRCSHDEVVEFIQQAG 518



 Score = 44.8 bits (101), Expect = 0.004
 Identities = 41/107 (38%), Positives = 51/107 (47%), Gaps = 14/107 (13%)

Query: 208 RTASVRQRPASS-RITAAELEELFQRQAVADAPGGNNAMMI-RSAFQGGANSPPYSPA-- 263
           R ASVRQRP S  RI+AAELE L  RQ V    G    M   + +  GG +S  Y+    
Sbjct: 569 RHASVRQRPGSGRRISAAELENLMVRQRVPSVQGSPYQMQYDQESLNGGYSSKKYNSVSD 628

Query: 264 ----KGPGKVYASVAEMKRSRAKLWSKCPGTLRREFH----STPDLA 302
               KG   V AS A + RS  +     P T   E++    STP L+
Sbjct: 629 MKRRKGQRNVVASSAGLNRSTFE--QAAPTTSTFEYNCSSRSTPQLS 673


>UniRef50_Q4TAT2 Cluster: Chromosome undetermined SCAF7261, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7261,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 1448

 Score = 52.4 bits (120), Expect = 2e-05
 Identities = 30/81 (37%), Positives = 40/81 (49%), Gaps = 1/81 (1%)

Query: 1   MECRTVVLH-RARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXK 59
           +E +T +L  R   GFGFVLRGAKA +P+ E  P+   PALQY                 
Sbjct: 878 IEEKTAILQKRESEGFGFVLRGAKAETPIEEFVPTPAFPALQYLESVDQGGVAWRAGLRT 937

Query: 60  GDFLVAINGEDVSAASHEHVV 80
           GDFL+ ++   +S      VV
Sbjct: 938 GDFLIEVSAGRLSPEQPAAVV 958


>UniRef50_Q4S4Q0 Cluster: Chromosome 2 SCAF14738, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 2
           SCAF14738, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 1101

 Score = 47.6 bits (108), Expect = 6e-04
 Identities = 22/64 (34%), Positives = 30/64 (46%)

Query: 24  ASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFLVAINGEDVSAASHEHVVELI 83
           A +P+ E  P+   PALQY                 GDFL+ +NG++V    H  VV +I
Sbjct: 716 AQTPIEEFTPTPAFPALQYLESVDEGGVAWRAGLRMGDFLIEVNGQNVVKVGHRQVVNMI 775

Query: 84  RNSG 87
           R  G
Sbjct: 776 RQGG 779


>UniRef50_Q4RJR1 Cluster: Chromosome 13 SCAF15035, whole genome
          shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
          Chromosome 13 SCAF15035, whole genome shotgun sequence
          - Tetraodon nigroviridis (Green puffer)
          Length = 1125

 Score = 46.8 bits (106), Expect = 0.001
 Identities = 23/64 (35%), Positives = 30/64 (46%)

Query: 24 ASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFLVAINGEDVSAASHEHVVELI 83
          A +P+ E  P+   PALQY                 GDFL+ +NG +V    H+ VV LI
Sbjct: 30 AETPIEEFTPTPAFPALQYLESVDVEGVAWRAGLRTGDFLIEVNGVNVIKLGHKQVVSLI 89

Query: 84 RNSG 87
          R  G
Sbjct: 90 RQGG 93


>UniRef50_UPI0000F211A9 Cluster: PREDICTED: similar to
            membrane-associated guanylate kinase-related 3 (MAGI-3);
            n=1; Danio rerio|Rep: PREDICTED: similar to
            membrane-associated guanylate kinase-related 3 (MAGI-3) -
            Danio rerio
          Length = 1279

 Score = 43.2 bits (97), Expect = 0.014
 Identities = 32/86 (37%), Positives = 40/86 (46%), Gaps = 13/86 (15%)

Query: 3    CRTVVLHRARRGFGFVLRGAKA-SSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGD 61
            C  V L R +RGFGF LRG K  +  L  LR +E  PAL+                  GD
Sbjct: 953  CYPVELERGQRGFGFSLRGGKEYNMGLFILRLAEDGPALK------------DGRIHVGD 1000

Query: 62   FLVAINGEDVSAASHEHVVELIRNSG 87
             +V INGE     +H   +ELI+  G
Sbjct: 1001 QIVEINGEPTQGITHTRAIELIQAGG 1026


>UniRef50_Q93566 Cluster: Putative uncharacterized protein; n=2;
           Caenorhabditis|Rep: Putative uncharacterized protein -
           Caenorhabditis elegans
          Length = 578

 Score = 41.1 bits (92), Expect = 0.055
 Identities = 20/78 (25%), Positives = 36/78 (46%)

Query: 10  RARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFLVAINGE 69
           ++  GFGF ++G  +    +     +    LQ+                KGD ++ +NG 
Sbjct: 54  KSETGFGFNVKGQVSEGGQLRSLNGQLYAPLQHVSAVLRRGAADQAGLRKGDRILEVNGL 113

Query: 70  DVSAASHEHVVELIRNSG 87
           +V  ++H  VV+LI+N G
Sbjct: 114 NVEGSTHRKVVDLIKNGG 131


>UniRef50_UPI0000DB7D47 Cluster: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 4
           (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG);
           n=3; Endopterygota|Rep: PREDICTED: similar to
           Tyrosine-protein phosphatase non-receptor type 4
           (Protein-tyrosine phosphatase MEG1) (PTPase-MEG1) (MEG)
           - Apis mellifera
          Length = 927

 Score = 37.5 bits (83), Expect = 0.68
 Identities = 18/28 (64%), Positives = 20/28 (71%)

Query: 59  KGDFLVAINGEDVSAASHEHVVELIRNS 86
           +GD +V ING DVS   HEHVV LIR S
Sbjct: 550 EGDQVVYINGIDVSGLLHEHVVNLIRQS 577


>UniRef50_A4RVJ8 Cluster: Predicted protein; n=1; Ostreococcus
            lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus
            lucimarinus CCE9901
          Length = 1451

 Score = 37.5 bits (83), Expect = 0.68
 Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 1/89 (1%)

Query: 221  ITAAELEELFQRQAVADAPGGNNAMMIRSAFQGGANSPPYSPAKGPGKVYASVAEMKRSR 280
            + AAEL+    R +V   PG + A+   SA+  G+  P    A G  +  A     +   
Sbjct: 1201 VAAAELKTAGVRVSVVTVPGADGAVP-SSAYYSGSPWPSKCTADGQCEFSAPYGGDRGHW 1259

Query: 281  AKLWSKCPGTLRREFHSTPDLAAELAPHP 309
               ++   G L R+++  P+LA ++  HP
Sbjct: 1260 GSWYTDANGDLTRDYNPGPELACQMRVHP 1288


>UniRef50_Q70Q02 Cluster: PDZ-domain factor 1; n=1; Echinococcus
          multilocularis|Rep: PDZ-domain factor 1 - Echinococcus
          multilocularis
          Length = 208

 Score = 37.5 bits (83), Expect = 0.68
 Identities = 15/28 (53%), Positives = 21/28 (75%)

Query: 60 GDFLVAINGEDVSAASHEHVVELIRNSG 87
          GDF+V +NGE++ + SH  VVELI+  G
Sbjct: 50 GDFVVEVNGENILSYSHPEVVELIKKGG 77


>UniRef50_UPI0000DB6C0C Cluster: PREDICTED: similar to Rhophilin
           CG8497-PA, isoform A; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Rhophilin CG8497-PA, isoform A -
           Apis mellifera
          Length = 660

 Score = 37.1 bits (82), Expect = 0.90
 Identities = 16/29 (55%), Positives = 21/29 (72%)

Query: 59  KGDFLVAINGEDVSAASHEHVVELIRNSG 87
           +GDF+V I  +DV  +SHE VV LI+ SG
Sbjct: 554 EGDFIVGIGDKDVKWSSHEQVVRLIKQSG 582


>UniRef50_Q5T2W1 Cluster: PDZ domain-containing protein 1
           (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter
           C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+)
           exchanger regulatory factor 3); n=24; Amniota|Rep: PDZ
           domain-containing protein 1 (CFTR-associated protein of
           70 kDa) (Na/Pi cotransporter C-terminal-associated
           protein) (NaPi-Cap1) (Na(+)/H(+) exchanger regulatory
           factor 3) - Homo sapiens (Human)
          Length = 519

 Score = 37.1 bits (82), Expect = 0.90
 Identities = 15/28 (53%), Positives = 21/28 (75%)

Query: 61  DFLVAINGEDVSAASHEHVVELIRNSGA 88
           D L+ +NGE+V  ASHE VVE ++ SG+
Sbjct: 178 DHLIEVNGENVEDASHEEVVEKVKKSGS 205



 Score = 35.1 bits (77), Expect = 3.6
 Identities = 14/27 (51%), Positives = 18/27 (66%)

Query: 61  DFLVAINGEDVSAASHEHVVELIRNSG 87
           D +VA+NGE V    H+ VVE+IR  G
Sbjct: 286 DLVVAVNGESVETLDHDSVVEMIRKGG 312


>UniRef50_UPI000065E2F5 Cluster: Regulator of G-protein signaling
          12 (RGS12).; n=1; Takifugu rubripes|Rep: Regulator of
          G-protein signaling 12 (RGS12). - Takifugu rubripes
          Length = 1267

 Score = 36.7 bits (81), Expect = 1.2
 Identities = 29/82 (35%), Positives = 39/82 (47%), Gaps = 16/82 (19%)

Query: 2  ECRTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGD 61
          E R+V + R R G+GF + G +   P +     E  PA                   +GD
Sbjct: 16 ELRSVEIIRGRAGYGFTISGQR---PCLLSGIQEGSPA-------------DVVGLKQGD 59

Query: 62 FLVAINGEDVSAASHEHVVELI 83
           ++AING DVS A HE VV+LI
Sbjct: 60 QIMAINGTDVSVALHETVVQLI 81


>UniRef50_UPI000065DD5D Cluster: Homolog of Homo sapiens "protein
            tyrosine phosphatase, non-receptor type 13 isoform 2;
            n=1; Takifugu rubripes|Rep: Homolog of Homo sapiens
            "protein tyrosine phosphatase, non-receptor type 13
            isoform 2 - Takifugu rubripes
          Length = 2538

 Score = 36.7 bits (81), Expect = 1.2
 Identities = 13/29 (44%), Positives = 23/29 (79%)

Query: 59   KGDFLVAINGEDVSAASHEHVVELIRNSG 87
            KGD +VA+NG+ +  A+H+  VE++R++G
Sbjct: 1470 KGDRVVAVNGKSLDGATHQQAVEILRDTG 1498


>UniRef50_Q4SQB7 Cluster: Chromosome 4 SCAF14533, whole genome shotgun
            sequence; n=1; Tetraodon nigroviridis|Rep: Chromosome 4
            SCAF14533, whole genome shotgun sequence - Tetraodon
            nigroviridis (Green puffer)
          Length = 2517

 Score = 36.7 bits (81), Expect = 1.2
 Identities = 13/29 (44%), Positives = 23/29 (79%)

Query: 59   KGDFLVAINGEDVSAASHEHVVELIRNSG 87
            KGD +VA+NG+ +  A+H+  VE++R++G
Sbjct: 1466 KGDRVVAVNGKSLEGATHQQAVEILRDTG 1494


>UniRef50_A6R1R5 Cluster: Putative uncharacterized protein; n=1;
           Ajellomyces capsulatus NAm1|Rep: Putative
           uncharacterized protein - Ajellomyces capsulatus NAm1
          Length = 908

 Score = 36.3 bits (80), Expect = 1.6
 Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 1/69 (1%)

Query: 210 ASVRQRPASSRITAAELEELFQRQAVADAPGGNNAMMIRSAFQGGANSPPYSPAKGPGKV 269
           + +R  P +  I++  + E  QRQAV+  PG +   ++  + Q     PP++P  G   +
Sbjct: 92  SQIRDVPDAVGISSETISEYSQRQAVSSTPGPSQNPLLSLSHQ-SYGLPPHAPTGGGKSL 150

Query: 270 YASVAEMKR 278
            A V  +KR
Sbjct: 151 IADVLMLKR 159


>UniRef50_Q9VRT8 Cluster: CG6619-PA; n=2; Drosophila
           melanogaster|Rep: CG6619-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 866

 Score = 35.9 bits (79), Expect = 2.1
 Identities = 19/81 (23%), Positives = 37/81 (45%), Gaps = 5/81 (6%)

Query: 4   RTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFL 63
           RT+++ +    +GF L+     S  +  +  E    + Y                +GD +
Sbjct: 130 RTIIVEKKNNSYGFTLQ-----SYGIHYKRDEELEMITYVDYVEYGGPAYRAGMREGDVI 184

Query: 64  VAINGEDVSAASHEHVVELIR 84
           ++ING+D+  A H+ +VE I+
Sbjct: 185 LSINGKDMEKADHKTIVEFIK 205


>UniRef50_Q13424 Cluster: Alpha-1-syntrophin; n=23;
           Gnathostomata|Rep: Alpha-1-syntrophin - Homo sapiens
           (Human)
          Length = 505

 Score = 35.9 bits (79), Expect = 2.1
 Identities = 11/28 (39%), Positives = 24/28 (85%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSG 87
           GD ++++NGED+S+A+H+  V++++ +G
Sbjct: 132 GDAILSVNGEDLSSATHDEAVQVLKKTG 159


>UniRef50_UPI00015B5174 Cluster: PREDICTED: similar to regulator
          of g protein signaling; n=1; Nasonia vitripennis|Rep:
          PREDICTED: similar to regulator of g protein signaling
          - Nasonia vitripennis
          Length = 1378

 Score = 35.5 bits (78), Expect = 2.7
 Identities = 16/30 (53%), Positives = 19/30 (63%)

Query: 60 GDFLVAINGEDVSAASHEHVVELIRNSGAL 89
          GD+LVA+NG  V  A H+ VV LI  S  L
Sbjct: 67 GDYLVAVNGHGVGKAPHDDVVRLIGRSNGL 96


>UniRef50_UPI00015B4313 Cluster: PREDICTED: similar to rhophilin;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           rhophilin - Nasonia vitripennis
          Length = 713

 Score = 35.5 bits (78), Expect = 2.7
 Identities = 16/29 (55%), Positives = 20/29 (68%)

Query: 59  KGDFLVAINGEDVSAASHEHVVELIRNSG 87
           +GDF+V I  +DV  ASHE VV LI+  G
Sbjct: 605 EGDFIVNIGDKDVKWASHEQVVRLIKQCG 633


>UniRef50_UPI0000E4706C Cluster: PREDICTED: similar to
           beta1-syntrophin; n=2; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to beta1-syntrophin -
           Strongylocentrotus purpuratus
          Length = 541

 Score = 35.5 bits (78), Expect = 2.7
 Identities = 13/28 (46%), Positives = 21/28 (75%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSG 87
           GD ++++NGED+  ASH+  V L++ SG
Sbjct: 158 GDAILSVNGEDLRDASHDEAVRLLKRSG 185


>UniRef50_Q4S7U1 Cluster: Chromosome 18 SCAF14712, whole genome
          shotgun sequence; n=10; Euteleostomi|Rep: Chromosome 18
          SCAF14712, whole genome shotgun sequence - Tetraodon
          nigroviridis (Green puffer)
          Length = 1510

 Score = 35.5 bits (78), Expect = 2.7
 Identities = 31/87 (35%), Positives = 42/87 (48%), Gaps = 17/87 (19%)

Query: 4  RTVVLHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFL 63
          R V + R R G+GF L G    SP +  R  +  PA                    GD++
Sbjct: 3  RAVEVARGRTGYGFTLSG---QSPCVLSRILKGSPA-------------DYVGLRSGDYI 46

Query: 64 VAINGEDVSAASHEHVVELI-RNSGAL 89
          +++N  +VS ASHE VV+LI R SG L
Sbjct: 47 LSVNDINVSKASHEDVVKLIGRCSGVL 73


>UniRef50_Q0VMQ8 Cluster: Peptide synthetase, putative; n=1;
           Alcanivorax borkumensis SK2|Rep: Peptide synthetase,
           putative - Alcanivorax borkumensis (strain SK2 / ATCC
           700651 / DSM 11573)
          Length = 1824

 Score = 35.5 bits (78), Expect = 2.7
 Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 17/134 (12%)

Query: 217 ASSRITAAELEELFQRQAVADAPGGNNAM---MIRSAFQGGANSPPYSP---AKGPGKVY 270
           A +R T   ++++ + Q + +  G    +   M+ +A++G   S  Y+P   A GP K+Y
Sbjct: 767 AFTRETFERMQQVLKPQRILNGYGPTETVVTPMLWAAYEGDTLSSAYAPIGHAVGPRKLY 826

Query: 271 ASVAEMKRS----RAKLWSKCPGTLRREFHSTPDLAAE-LAPHP-----PRTRSTDDVHV 320
               ++ R       +L+      L R +H  PDL AE   P P      R   T D+ V
Sbjct: 827 VLDQDLNRVPVGVAGELYIGNEVGLARGYHQRPDLTAERFLPDPFGEPGERMYRTGDL-V 885

Query: 321 HYDDECVVLGCGRV 334
            Y D+ V+   GRV
Sbjct: 886 KYRDDGVMEYLGRV 899


>UniRef50_Q0VMQ7 Cluster: Peptide synthetase, putative; n=1;
           Alcanivorax borkumensis SK2|Rep: Peptide synthetase,
           putative - Alcanivorax borkumensis (strain SK2 / ATCC
           700651 / DSM 11573)
          Length = 3600

 Score = 35.5 bits (78), Expect = 2.7
 Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 17/134 (12%)

Query: 217 ASSRITAAELEELFQRQAVADAPGGNNAM---MIRSAFQGGANSPPYSP---AKGPGKVY 270
           A +R T   ++++ + Q + +  G    +   M+ +A++G   S  Y+P   A GP K+Y
Sbjct: 738 AFTRETFERMQQVLKPQRILNGYGPTETVVTPMLWAAYEGDTLSSAYAPIGHAVGPRKLY 797

Query: 271 ASVAEMKRS----RAKLWSKCPGTLRREFHSTPDLAAE-LAPHP-----PRTRSTDDVHV 320
               ++ R       +L+      L R +H  PDL AE   P P      R   T D+ V
Sbjct: 798 VLDQDLNRVPVGVAGELYIGNEVGLARGYHQRPDLTAERFLPDPFGEPGERMYRTGDL-V 856

Query: 321 HYDDECVVLGCGRV 334
            Y D+ V+   GRV
Sbjct: 857 KYRDDGVMEYLGRV 870



 Score = 35.5 bits (78), Expect = 2.7
 Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 17/134 (12%)

Query: 217  ASSRITAAELEELFQRQAVADAPGGNNAM---MIRSAFQGGANSPPYSP---AKGPGKVY 270
            A +R T   ++++ + Q + +  G    +   M+ +A++G   S  Y+P   A GP K+Y
Sbjct: 2219 AFTRETFERMQQVLKPQRILNGYGPTETVVTPMLWAAYEGDTLSSAYAPIGHAVGPRKLY 2278

Query: 271  ASVAEMKRS----RAKLWSKCPGTLRREFHSTPDLAAE-LAPHP-----PRTRSTDDVHV 320
                ++ R       +L+      L R +H  PDL AE   P P      R   T D+ V
Sbjct: 2279 VLDQDLNRVPVGVAGELYIGNEVGLARGYHQRPDLTAERFLPDPFGEPGERMYRTGDL-V 2337

Query: 321  HYDDECVVLGCGRV 334
             Y D+ V+   GRV
Sbjct: 2338 KYRDDGVMEYLGRV 2351


>UniRef50_Q9VFD3 Cluster: CG31304-PA; n=6; Diptera|Rep: CG31304-PA -
           Drosophila melanogaster (Fruit fly)
          Length = 1363

 Score = 35.5 bits (78), Expect = 2.7
 Identities = 13/25 (52%), Positives = 20/25 (80%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIR 84
           GD ++A+NGEDV  A  +HV++L+R
Sbjct: 102 GDQILAVNGEDVKDAPRDHVIQLVR 126


>UniRef50_Q92614 Cluster: Myosin-XVIIIa; n=59; Euteleostomi|Rep:
           Myosin-XVIIIa - Homo sapiens (Human)
          Length = 2054

 Score = 35.5 bits (78), Expect = 2.7
 Identities = 26/86 (30%), Positives = 39/86 (45%), Gaps = 6/86 (6%)

Query: 4   RTVVLHRARRG-FGFVLRGAKASSPLMELRPS-ERCPALQYXXXXXXXXXXXXXXXXKGD 61
           R + L R   G FGF LR     + +++  P  + C  + +                 GD
Sbjct: 219 RELELQRRPTGDFGFSLR----RTTMLDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGD 274

Query: 62  FLVAINGEDVSAASHEHVVELIRNSG 87
            LV ING +V + S + +VE+IR SG
Sbjct: 275 RLVEINGHNVESKSRDEIVEMIRQSG 300


>UniRef50_UPI0001560013 Cluster: PREDICTED: hypothetical protein;
          n=1; Equus caballus|Rep: PREDICTED: hypothetical
          protein - Equus caballus
          Length = 393

 Score = 35.1 bits (77), Expect = 3.6
 Identities = 11/28 (39%), Positives = 23/28 (82%)

Query: 60 GDFLVAINGEDVSAASHEHVVELIRNSG 87
          GD ++++NGED+S+A+H+  V+ ++ +G
Sbjct: 47 GDAILSVNGEDLSSATHDEAVQALKKTG 74


>UniRef50_UPI0000F1FDA9 Cluster: PREDICTED: hypothetical protein;
           n=2; Danio rerio|Rep: PREDICTED: hypothetical protein -
           Danio rerio
          Length = 501

 Score = 35.1 bits (77), Expect = 3.6
 Identities = 26/86 (30%), Positives = 40/86 (46%), Gaps = 14/86 (16%)

Query: 4   RTVVLHRARRGFGFVLRGAKASSPLME--LRPSERCPALQYXXXXXXXXXXXXXXXXKGD 61
           +T+ L +  +G+GF+LR  K  S  +   LR  + C   +                  G+
Sbjct: 263 KTLHLTQGPQGYGFLLRQEKLRSGRIAHILREIDPCSPAE------------TAGMEDGE 310

Query: 62  FLVAINGEDVSAASHEHVVELIRNSG 87
            ++A+NGE V  A HE +V  IR SG
Sbjct: 311 IVLAVNGEQVEDAEHEGIVSKIRQSG 336


>UniRef50_Q6EHH9 Cluster: Frizzled-8 associated multidomain protein;
            n=3; Xenopus|Rep: Frizzled-8 associated multidomain
            protein - Xenopus laevis (African clawed frog)
          Length = 2500

 Score = 35.1 bits (77), Expect = 3.6
 Identities = 12/29 (41%), Positives = 22/29 (75%)

Query: 59   KGDFLVAINGEDVSAASHEHVVELIRNSG 87
            KGD ++++NG  +  A+H+  VE++RN+G
Sbjct: 1395 KGDRVLSVNGTSLEGATHKQAVEMLRNTG 1423


>UniRef50_Q4SLD5 Cluster: Chromosome 7 SCAF14557, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 7
           SCAF14557, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 370

 Score = 35.1 bits (77), Expect = 3.6
 Identities = 13/28 (46%), Positives = 19/28 (67%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSG 87
           GD L+ +NGE V +  H+ +VE +R SG
Sbjct: 273 GDLLLEVNGESVESLRHQEIVERVRQSG 300


>UniRef50_Q4H4B6 Cluster: Scribble1; n=16; Euteleostomi|Rep:
           Scribble1 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 1724

 Score = 35.1 bits (77), Expect = 3.6
 Identities = 15/29 (51%), Positives = 19/29 (65%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSGA 88
           GD L+ +NG D+  A H   VE +RNSGA
Sbjct: 780 GDKLLEVNGVDLHGAEHHTAVEALRNSGA 808


>UniRef50_A7SS78 Cluster: Predicted protein; n=3; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 1030

 Score = 35.1 bits (77), Expect = 3.6
 Identities = 19/80 (23%), Positives = 35/80 (43%), Gaps = 5/80 (6%)

Query: 8   LHRARRGFGFVLRGAKASSPLMELRPSERCPALQYXXXXXXXXXXXXXXXXKGDFLVAIN 67
           +HR  +G G  + G K S+P       E    +                   GD ++ +N
Sbjct: 571 IHRDTKGLGINIAGGKGSTPY-----KENDEGIFISRISENGPAGRDGILHVGDKILKVN 625

Query: 68  GEDVSAASHEHVVELIRNSG 87
           G D+S A+H   V++++++G
Sbjct: 626 GVDISNATHHQAVDVLKSTG 645


>UniRef50_Q7SAE8 Cluster: Predicted protein; n=1; Neurospora
           crassa|Rep: Predicted protein - Neurospora crassa
          Length = 486

 Score = 35.1 bits (77), Expect = 3.6
 Identities = 23/68 (33%), Positives = 34/68 (50%), Gaps = 1/68 (1%)

Query: 256 NSPPYSPAKGPGKVYASVAEMKRSRAKLWSKCPGTLRREFHSTPDLAAELAPHPPRTRST 315
           N+ P SP + PG   A      + RA   +K   TLR+   +   ++AE A  PP+ RS 
Sbjct: 83  NNRPTSP-QTPGSPGALQRTTSQVRAAGQAKARATLRKRQRTDSVMSAENADKPPKYRSR 141

Query: 316 DDVHVHYD 323
             + V+YD
Sbjct: 142 SMIIVYYD 149


>UniRef50_A7E5X2 Cluster: Putative uncharacterized protein; n=1;
           Sclerotinia sclerotiorum 1980|Rep: Putative
           uncharacterized protein - Sclerotinia sclerotiorum 1980
          Length = 1735

 Score = 35.1 bits (77), Expect = 3.6
 Identities = 19/64 (29%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 252 QGGANSPPYSPAKGPGKVYASVAEMKRSRAKLWSKCPGTLRREFHSTPDLAAELAPHPPR 311
           Q   N PP +P    G  +A    M+ ++   +   PG + RE +ST  ++ ++ P PP 
Sbjct: 249 QASYNPPPTAPYPVNGDTFAEDDYMRNTQMPTYPNFPGGVLRE-NSTDSVSQDIPPIPPP 307

Query: 312 TRST 315
            RS+
Sbjct: 308 KRSS 311


>UniRef50_P28191 Cluster: Tyrosine-protein phosphatase 1; n=4;
           Caenorhabditis|Rep: Tyrosine-protein phosphatase 1 -
           Caenorhabditis elegans
          Length = 1026

 Score = 35.1 bits (77), Expect = 3.6
 Identities = 14/28 (50%), Positives = 22/28 (78%)

Query: 59  KGDFLVAINGEDVSAASHEHVVELIRNS 86
           +GD ++ I+G DVS  SH+HVV+ IR++
Sbjct: 662 EGDQVLFIDGRDVSTMSHDHVVQFIRSA 689


>UniRef50_Q5JV73 Cluster: FERM and PDZ domain-containing protein 3;
           n=10; Mammalia|Rep: FERM and PDZ domain-containing
           protein 3 - Homo sapiens (Human)
          Length = 1810

 Score = 35.1 bits (77), Expect = 3.6
 Identities = 16/27 (59%), Positives = 21/27 (77%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNS 86
           GD +VAIN EDVS A  E ++ELIR++
Sbjct: 93  GDQIVAINEEDVSEAPRERLIELIRSA 119


>UniRef50_UPI0000DB78FC Cluster: PREDICTED: similar to locomotion
          defects CG5248-PD, isoform D; n=1; Apis mellifera|Rep:
          PREDICTED: similar to locomotion defects CG5248-PD,
          isoform D - Apis mellifera
          Length = 632

 Score = 34.7 bits (76), Expect = 4.8
 Identities = 16/31 (51%), Positives = 23/31 (74%), Gaps = 1/31 (3%)

Query: 60 GDFLVAINGEDVSAASHEHVVELI-RNSGAL 89
          GD+LV++NG +VS   H+ VV+LI R+ G L
Sbjct: 56 GDYLVSVNGHNVSKLPHDDVVQLIGRSKGIL 86


>UniRef50_UPI0000D577C0 Cluster: PREDICTED: similar to CG31304-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG31304-PA - Tribolium castaneum
          Length = 1248

 Score = 34.7 bits (76), Expect = 4.8
 Identities = 13/25 (52%), Positives = 18/25 (72%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIR 84
           GD ++ +NGEDV  A  EHV+ L+R
Sbjct: 160 GDQILTVNGEDVKMAPREHVISLVR 184


>UniRef50_Q4T9U1 Cluster: Chromosome undetermined SCAF7497, whole
           genome shotgun sequence; n=3; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7497,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 653

 Score = 34.7 bits (76), Expect = 4.8
 Identities = 13/30 (43%), Positives = 21/30 (70%)

Query: 59  KGDFLVAINGEDVSAASHEHVVELIRNSGA 88
           +GD++VA++G+D   A H  VV L++N  A
Sbjct: 539 EGDYIVAVDGQDCKWAKHAEVVHLLKNCSA 568


>UniRef50_Q4ST81 Cluster: Chromosome undetermined SCAF14284, whole
          genome shotgun sequence; n=8; Euteleostomi|Rep:
          Chromosome undetermined SCAF14284, whole genome shotgun
          sequence - Tetraodon nigroviridis (Green puffer)
          Length = 83

 Score = 34.7 bits (76), Expect = 4.8
 Identities = 12/29 (41%), Positives = 22/29 (75%)

Query: 59 KGDFLVAINGEDVSAASHEHVVELIRNSG 87
          KGD ++++NG D+S+A+HE     ++N+G
Sbjct: 43 KGDRILSVNGVDLSSATHEQAAAALKNAG 71


>UniRef50_Q64512 Cluster: Tyrosine-protein phosphatase non-receptor
            type 13; n=19; Eumetazoa|Rep: Tyrosine-protein
            phosphatase non-receptor type 13 - Mus musculus (Mouse)
          Length = 2453

 Score = 34.7 bits (76), Expect = 4.8
 Identities = 13/29 (44%), Positives = 21/29 (72%)

Query: 59   KGDFLVAINGEDVSAASHEHVVELIRNSG 87
            KGD ++A+NG  +  A+H+  VE +RN+G
Sbjct: 1403 KGDRVLAVNGVSLEGATHKQAVETLRNTG 1431


>UniRef50_Q12923 Cluster: Tyrosine-protein phosphatase non-receptor
            type 13; n=12; Amniota|Rep: Tyrosine-protein phosphatase
            non-receptor type 13 - Homo sapiens (Human)
          Length = 2485

 Score = 34.7 bits (76), Expect = 4.8
 Identities = 13/29 (44%), Positives = 21/29 (72%)

Query: 59   KGDFLVAINGEDVSAASHEHVVELIRNSG 87
            KGD ++A+NG  +  A+H+  VE +RN+G
Sbjct: 1414 KGDRVLAVNGVSLEGATHKQAVETLRNTG 1442


>UniRef50_UPI0000607CB5 Cluster: PREDICTED: similar to two
           transmembrane domain family member A; n=2; Theria|Rep:
           PREDICTED: similar to two transmembrane domain family
           member A - Mus musculus
          Length = 637

 Score = 34.3 bits (75), Expect = 6.3
 Identities = 34/162 (20%), Positives = 53/162 (32%), Gaps = 5/162 (3%)

Query: 159 ARAKSMVAGLENGGEKEESCEPLSAAGKSSSAESVQQPXXXXXXXXXXPRTASVRQRPAS 218
           A A + V    +GG     C P  + G+ S+  S+             P     R R   
Sbjct: 353 AAATATVTAAASGGSSPAPCSPTGSWGRQSTTSSLV--GSSLSAFALLPLQGD-RDRDGD 409

Query: 219 SRITAAELEELFQRQAVADAPGGNNAMMIRS--AFQGGANSPPYSPAKGPGKVYASVAEM 276
           S   +         +   D P G   + +      +GGA      P +  G   A  A  
Sbjct: 410 SEGASCSWHRPPGERGSRDLPRGELDLSLTDLRGAEGGARWASCEPGEPEGAKTARTARG 469

Query: 277 KRSRAKLWSKCPGTLRREFHSTPDLAAELAPHPPRTRSTDDV 318
           +  R     +     RR     PD  A  +P PP + S +++
Sbjct: 470 QGGRLPRTRRYAAWRRRSTSGLPDYRAPPSPEPPPSSSAENL 511


>UniRef50_A5PKP4 Cluster: LOC100101295 protein; n=1; Xenopus
           laevis|Rep: LOC100101295 protein - Xenopus laevis
           (African clawed frog)
          Length = 416

 Score = 34.3 bits (75), Expect = 6.3
 Identities = 26/88 (29%), Positives = 39/88 (44%), Gaps = 17/88 (19%)

Query: 4   RTVVLHRAR--RGFGFVLRGAKASSPLMELRPSERCPALQ--YXXXXXXXXXXXXXXXXK 59
           RT  LH  +  +G+GF+LR              E+CPA Q  +                +
Sbjct: 265 RTRKLHLVKGPQGYGFLLR-------------QEKCPAGQGQFLREIDPGLPAEDAGMRE 311

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSG 87
           GD L+ +NG+ V    HE +V +I+ SG
Sbjct: 312 GDCLLGVNGQSVEGLEHEDIVSMIQESG 339


>UniRef50_Q9ZWA1 Cluster: F11M21.28 protein; n=3; Arabidopsis
           thaliana|Rep: F11M21.28 protein - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 393

 Score = 34.3 bits (75), Expect = 6.3
 Identities = 23/106 (21%), Positives = 44/106 (41%), Gaps = 1/106 (0%)

Query: 212 VRQRPASSRITAAELEELFQRQAVADAPGGNNAMMIRSAFQGGANSPPYSPAKGPGKVYA 271
           +R R AS+   AA    +  +  +++     ++M +  A Q  ++SP  +P       +A
Sbjct: 248 LRNRAASAVSAAAAAGSMNYKDVLSELVNSLDSMSLAEALQASSSSPVTTPVSAAAAAFA 307

Query: 272 SVAEMKRSRAKLWSKCPGTLRREFHSTPDLAAELAPHPPRTRSTDD 317
           S   +   R  L  + P +   +F  +P   + L   P     +DD
Sbjct: 308 SSCGLSNQRLHLQQQQPSS-PLQFALSPSTPSYLTNSPQANFFSDD 352


>UniRef50_Q9XYY9 Cluster: Rhophilin; n=3; Diptera|Rep: Rhophilin -
           Drosophila melanogaster (Fruit fly)
          Length = 718

 Score = 34.3 bits (75), Expect = 6.3
 Identities = 15/30 (50%), Positives = 22/30 (73%)

Query: 59  KGDFLVAINGEDVSAASHEHVVELIRNSGA 88
           +GDF+V I G DV   SH+ VV+LI++ G+
Sbjct: 606 EGDFIVEIAGVDVKWYSHQQVVQLIQSCGS 635


>UniRef50_Q9NDP4 Cluster: Tyrosine phosphatase; n=1; Ciona
           intestinalis|Rep: Tyrosine phosphatase - Ciona
           intestinalis (Transparent sea squirt)
          Length = 987

 Score = 34.3 bits (75), Expect = 6.3
 Identities = 14/28 (50%), Positives = 21/28 (75%)

Query: 59  KGDFLVAINGEDVSAASHEHVVELIRNS 86
           +GD ++ ING D+S+ SHE VV  IR++
Sbjct: 599 EGDEVLQINGRDISSHSHEQVVRFIRST 626


>UniRef50_A7RKG0 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 404

 Score = 34.3 bits (75), Expect = 6.3
 Identities = 14/29 (48%), Positives = 21/29 (72%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSGA 88
           GD ++ ING +V   +H HVVEL++ SG+
Sbjct: 256 GDHILEINGLNVRNKTHAHVVELLKGSGS 284


>UniRef50_A7RJG2 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 2195

 Score = 34.3 bits (75), Expect = 6.3
 Identities = 14/29 (48%), Positives = 21/29 (72%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSGA 88
           GD ++ ING +V   +H HVVEL++ SG+
Sbjct: 360 GDHILEINGLNVRNKTHAHVVELLKGSGS 388


>UniRef50_Q8N3D4 Cluster: EH domain-binding protein 1-like protein 1;
            n=4; Catarrhini|Rep: EH domain-binding protein 1-like
            protein 1 - Homo sapiens (Human)
          Length = 1523

 Score = 34.3 bits (75), Expect = 6.3
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 3/81 (3%)

Query: 179  EPLSAAGKSSSAESVQQPXXXXXXXXXXP---RTASVRQRPASSRITAAELEELFQRQAV 235
            +P  A G  ++A+S Q P          P     A +++   +S+   AEL+ L Q Q  
Sbjct: 1317 DPSPAPGPPTAADSQQPPGGSSPSEEPPPSPGEEAGLQRFQDTSQYVCAELQALEQEQRQ 1376

Query: 236  ADAPGGNNAMMIRSAFQGGAN 256
             D       M +RS  + GAN
Sbjct: 1377 IDGRAAEVEMQLRSLMESGAN 1397


>UniRef50_UPI000065DCC0 Cluster: PDZ domain-containing protein 1
           (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter
           C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+)
           exchanger regulatory factor 3) (Sodium-hydrogen
           exchanger regulatory factor 3).; n=1; Takifugu
           rubripes|Rep: PDZ domain-containing protein 1
           (CFTR-associated protein of 70 kDa) (Na/Pi cotransporter
           C-terminal-associated protein) (NaPi-Cap1) (Na(+)/H(+)
           exchanger regulatory factor 3) (Sodium-hydrogen
           exchanger regulatory factor 3). - Takifugu rubripes
          Length = 527

 Score = 33.9 bits (74), Expect = 8.4
 Identities = 16/28 (57%), Positives = 19/28 (67%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSG 87
           GD LV ING +V   SH+ VVE+I  SG
Sbjct: 434 GDILVEINGINVENRSHDEVVEMIHLSG 461


>UniRef50_Q5TTQ8 Cluster: ENSANGP00000025427; n=2; Culicidae|Rep:
          ENSANGP00000025427 - Anopheles gambiae str. PEST
          Length = 641

 Score = 33.9 bits (74), Expect = 8.4
 Identities = 14/24 (58%), Positives = 19/24 (79%)

Query: 60 GDFLVAINGEDVSAASHEHVVELI 83
          GDFL+++NG +VS   HE VV+LI
Sbjct: 52 GDFLISVNGLNVSKLPHESVVQLI 75


>UniRef50_Q9NY99 Cluster: Gamma-2-syntrophin; n=22;
           Euteleostomi|Rep: Gamma-2-syntrophin - Homo sapiens
           (Human)
          Length = 539

 Score = 33.9 bits (74), Expect = 8.4
 Identities = 14/28 (50%), Positives = 20/28 (71%)

Query: 60  GDFLVAINGEDVSAASHEHVVELIRNSG 87
           GD ++ +NG  V  A+HE VV L+RN+G
Sbjct: 118 GDAVLQVNGIHVENATHEEVVHLLRNAG 145


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.315    0.129    0.380 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 362,906,619
Number of Sequences: 1657284
Number of extensions: 11403777
Number of successful extensions: 29632
Number of sequences better than 10.0: 79
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 29460
Number of HSP's gapped (non-prelim): 161
length of query: 433
length of database: 575,637,011
effective HSP length: 103
effective length of query: 330
effective length of database: 404,936,759
effective search space: 133629130470
effective search space used: 133629130470
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.6 bits)
S2: 74 (33.9 bits)

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