Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000849-TA|BGIBMGA000849-PA|IPR002110|Ankyrin,
IPR001452|Src homology-3, IPR011511|Variant SH3
(523 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
DQ152234-1|AAZ77790.1| 707|Homo sapiens Shank2E protein. 392 e-108
AF163302-1|AAD45121.1| 2161|Homo sapiens somatostatin receptor i... 344 4e-94
AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kina... 94 1e-18
AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein. 94 1e-18
AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2 pro... 94 1e-18
U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein. 93 2e-18
U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein. 93 2e-18
AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 93 2e-18
AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 93 2e-18
AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 93 2e-18
AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranv... 93 2e-18
AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranv... 93 2e-18
AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1 var... 93 2e-18
BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein. 90 2e-17
AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone met... 90 2e-17
AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lys... 90 2e-17
AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lys... 90 2e-17
AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein. 90 2e-17
AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein. 90 2e-17
AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens ... 87 1e-16
BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein. 85 6e-16
BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein. 85 6e-16
BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein. 85 6e-16
BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin... 84 1e-15
U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein. 83 2e-15
X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2... 83 3e-15
X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for ... 83 3e-15
M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein. 83 3e-15
AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4 var... 83 3e-15
AK125360-1|BAC86146.1| 588|Homo sapiens protein ( Homo sapiens ... 81 1e-14
BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein pr... 80 2e-14
BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein. 80 2e-14
AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens ... 80 2e-14
AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein. 80 2e-14
Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein. 80 2e-14
X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein. 80 2e-14
BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein pr... 80 2e-14
U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein. 79 3e-14
U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein. 79 3e-14
D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein pro... 79 3e-14
BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 79 3e-14
BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 79 3e-14
BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein. 79 3e-14
BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein. 79 3e-14
BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein. 79 3e-14
AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosop... 79 3e-14
AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4 (Droso... 79 3e-14
AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4 (Droso... 79 3e-14
AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosop... 79 3e-14
AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens ... 79 3e-14
AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein. 79 3e-14
BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein. 78 7e-14
BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein. 78 7e-14
BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein. 78 9e-14
BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS... 77 1e-13
AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6... 77 1e-13
AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6... 77 1e-13
AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens ... 77 1e-13
AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein pr... 77 1e-13
AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteini... 77 1e-13
X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein. 77 2e-13
DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protei... 77 2e-13
BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protei... 77 2e-13
BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting se... 77 2e-13
BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting se... 77 2e-13
BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6... 77 2e-13
AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein. 77 2e-13
AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protei... 77 2e-13
AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protei... 77 2e-13
AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protei... 77 2e-13
AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein. 77 2e-13
AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein DK... 77 2e-13
AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specifici... 77 2e-13
AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein. 77 2e-13
X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein. 77 2e-13
BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lys... 77 2e-13
BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lys... 77 2e-13
BC075088-1|AAH75088.1| 453|Homo sapiens ankyrin repeat and SOCS... 77 2e-13
BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein. 77 2e-13
BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein. 77 2e-13
BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein. 77 2e-13
BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein. 77 2e-13
BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein. 77 2e-13
AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated transc... 77 2e-13
AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated transc... 77 2e-13
AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic histone-ly... 77 2e-13
AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic histone-ly... 77 2e-13
AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic histone-ly... 77 2e-13
AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic histone-ly... 77 2e-13
AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic histone-ly... 77 2e-13
AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic histone-ly... 77 2e-13
AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic histone-ly... 77 2e-13
AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic histone-ly... 77 2e-13
AK054727-1|BAB70800.1| 453|Homo sapiens protein ( Homo sapiens ... 77 2e-13
AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein. 77 2e-13
AF403034-1|AAL57353.1| 253|Homo sapiens ankyrin repeat domain-c... 77 2e-13
AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein. 77 2e-13
BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein. 76 3e-13
AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens ... 76 3e-13
AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein. 76 3e-13
BC100877-1|AAI00878.1| 241|Homo sapiens ASB15 protein protein. 76 4e-13
BC100876-1|AAI00877.1| 241|Homo sapiens ASB15 protein protein. 76 4e-13
BC100875-1|AAI00876.1| 241|Homo sapiens ASB15 protein protein. 76 4e-13
BC100874-1|AAI00875.1| 241|Homo sapiens ASB15 protein protein. 76 4e-13
AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens ... 76 4e-13
BC107759-1|AAI07760.1| 360|Homo sapiens ankyrin repeat domain 2... 75 5e-13
AL359388-4|CAI14194.1| 333|Homo sapiens ankyrin repeat domain 2... 75 5e-13
AL355315-9|CAI15463.1| 333|Homo sapiens ankyrin repeat domain 2... 75 5e-13
AJ583444-1|CAE47432.1| 449|Homo sapiens ankyrin repeat protein ... 75 5e-13
AJ304805-1|CAC19412.1| 333|Homo sapiens skeletal muscle ankyrin... 75 5e-13
AJ304804-1|CAC19411.1| 333|Homo sapiens skeletal muscle ankyrin... 75 5e-13
AB058599-1|BAB60958.1| 333|Homo sapiens ankyrin-repeat protein ... 75 5e-13
AF308292-1|AAG48260.1| 352|Homo sapiens serologically defined b... 75 8e-13
AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin... 73 2e-12
AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin... 73 2e-12
AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin... 73 2e-12
AF159164-1|AAD45345.1| 544|Homo sapiens ankyrin repeat-containi... 72 4e-12
M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein. 72 6e-12
AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1, transl... 72 6e-12
AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1, transl... 72 6e-12
AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein. 72 6e-12
AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein va... 72 6e-12
AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6... 71 8e-12
AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6... 71 8e-12
U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein. 71 1e-11
AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein pr... 71 1e-11
AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein. 71 1e-11
AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein. 71 1e-11
X83703-1|CAA58676.1| 319|Homo sapiens nuclear protein protein. 70 2e-11
BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 70 2e-11
BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1 (Dro... 70 2e-11
BC018667-1|AAH18667.1| 319|Homo sapiens ankyrin repeat domain 1... 70 2e-11
AY903446-1|AAX23581.1| 319|Homo sapiens liver ankyrin repeat do... 70 2e-11
AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein. 70 2e-11
AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein. 70 2e-11
AL590622-4|CAC70101.1| 319|Homo sapiens ankyrin repeat domain 1... 70 2e-11
AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS... 70 2e-11
BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein. 69 3e-11
BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 2... 69 3e-11
BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS... 69 3e-11
BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS... 69 3e-11
AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein pr... 69 3e-11
AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein. 69 3e-11
AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens ... 69 3e-11
AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein. 69 3e-11
AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein. 69 3e-11
AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS... 69 3e-11
DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinas... 69 4e-11
BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein pr... 69 4e-11
BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinas... 69 4e-11
BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinas... 69 4e-11
BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinas... 69 4e-11
AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat ... 69 4e-11
AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosi... 69 4e-11
AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinas... 69 4e-11
BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein. 69 5e-11
BC016490-1|AAH16490.1| 1030|Homo sapiens MIB2 protein protein. 69 5e-11
AL691432-4|CAM12833.1| 919|Homo sapiens mindbomb homolog 2 (Dro... 69 5e-11
AL691432-3|CAM12832.1| 753|Homo sapiens mindbomb homolog 2 (Dro... 69 5e-11
AL691432-2|CAM12831.1| 999|Homo sapiens mindbomb homolog 2 (Dro... 69 5e-11
AL691432-1|CAM12830.1| 948|Homo sapiens mindbomb homolog 2 (Dro... 69 5e-11
AK098785-1|BAC05413.1| 802|Homo sapiens protein ( Homo sapiens ... 69 5e-11
AK097106-1|BAC04952.1| 819|Homo sapiens protein ( Homo sapiens ... 69 5e-11
AK096295-1|BAC04752.1| 681|Homo sapiens protein ( Homo sapiens ... 69 5e-11
AK095914-1|BAC04646.1| 681|Homo sapiens protein ( Homo sapiens ... 69 5e-11
AK091610-1|BAC03707.1| 645|Homo sapiens protein ( Homo sapiens ... 69 5e-11
AB097000-1|BAC77353.1| 999|Homo sapiens putative NFkB activatin... 69 5e-11
AB076693-1|BAC00994.1| 1009|Homo sapiens skeletrophin gamma prot... 69 5e-11
AB076692-1|BAC00993.1| 948|Homo sapiens skeletrophin beta protein. 69 5e-11
AB076691-1|BAC00992.1| 999|Homo sapiens skeletrophin alpha prot... 69 5e-11
AB074480-1|BAB92950.1| 1013|Homo sapiens skeletrophin protein. 69 5e-11
AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS... 68 7e-11
AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated transc... 68 7e-11
BC037542-1|AAH37542.1| 999|Homo sapiens MIB2 protein protein. 68 9e-11
BC063581-1|AAH63581.1| 274|Homo sapiens ankyrin repeat and SOCS... 67 1e-10
AK222974-1|BAD96694.1| 274|Homo sapiens ankyrin repeat and SOCS... 67 1e-10
AK222958-1|BAD96678.1| 274|Homo sapiens ankyrin repeat and SOCS... 67 1e-10
AK026204-1|BAB15392.1| 274|Homo sapiens protein ( Homo sapiens ... 67 1e-10
AF451994-1|AAP97683.1| 318|Homo sapiens ankyrin repeat-containi... 67 1e-10
U76638-1|AAB38316.1| 777|Homo sapiens BRCA1-associated RING dom... 67 2e-10
BC126426-1|AAI26427.1| 777|Homo sapiens BRCA1 associated RING d... 67 2e-10
AK223409-1|BAD97129.1| 777|Homo sapiens BRCA1 associated RING d... 67 2e-10
AF038042-1|AAB99978.1| 777|Homo sapiens BRCA1-associated RING d... 67 2e-10
AC016708-1|AAX93130.1| 777|Homo sapiens unknown protein. 67 2e-10
AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein p... 66 2e-10
U05681-1|AAC51348.1| 368|Homo sapiens B-cell leukemia/lymphoma ... 66 3e-10
M69043-1|AAA16489.1| 317|Homo sapiens MAD3 protein. 66 3e-10
M31732-1|AAA51815.1| 446|Homo sapiens BCL3 protein. 66 3e-10
BT007091-1|AAP35754.1| 317|Homo sapiens nuclear factor of kappa... 66 3e-10
BC064993-1|AAH64993.1| 446|Homo sapiens B-cell CLL/lymphoma 3 p... 66 3e-10
BC004983-1|AAH04983.1| 317|Homo sapiens nuclear factor of kappa... 66 3e-10
BC002601-1|AAH02601.1| 317|Homo sapiens nuclear factor of kappa... 66 3e-10
AY496422-1|AAR29599.1| 317|Homo sapiens nuclear factor of kappa... 66 3e-10
AY033600-1|AAK51149.1| 317|Homo sapiens NFKBIA protein. 66 3e-10
AJ249294-1|CAB65556.2| 317|Homo sapiens IkBa protein. 66 3e-10
BC126428-1|AAI26429.1| 777|Homo sapiens BRCA1 associated RING d... 66 4e-10
AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein. 66 4e-10
AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein. 66 4e-10
AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat... 65 5e-10
Y10601-1|CAA71610.1| 1119|Homo sapiens ankyrin-like protein prot... 65 7e-10
BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 1... 64 9e-10
AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 1... 64 9e-10
AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens ... 64 9e-10
AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment e... 64 9e-10
AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein. 64 9e-10
CR457336-1|CAG33617.1| 288|Homo sapiens ASB8 protein. 64 1e-09
BC001321-1|AAH01321.1| 288|Homo sapiens ankyrin repeat and SOCS... 64 1e-09
AK024908-1|BAB15033.1| 288|Homo sapiens NP3) mRNA. protein. 64 1e-09
D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein. 64 2e-09
BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome, ma... 64 2e-09
AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome, ma... 64 2e-09
AB051515-1|BAB21819.1| 1644|Homo sapiens KIAA1728 protein protein. 64 2e-09
AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit ... 64 2e-09
BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome, ma... 63 2e-09
AL031177-4|CAI43134.1| 193|Homo sapiens proteasome (prosome, ma... 63 2e-09
DQ388145-2|ABD72216.1| 1482|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388144-2|ABD72214.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388143-2|ABD72212.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388142-2|ABD72210.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388141-2|ABD72208.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388140-2|ABD72206.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388139-2|ABD72204.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388138-2|ABD72202.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388137-2|ABD72200.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388136-2|ABD72198.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388135-2|ABD72196.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388134-2|ABD72194.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388133-2|ABD72192.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388132-2|ABD72190.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388131-2|ABD72188.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388130-2|ABD72186.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388129-2|ABD72184.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ388128-2|ABD72182.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ356264-2|ABC87066.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ356263-2|ABC87064.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ356262-2|ABC87062.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ356261-2|ABC87060.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ356260-2|ABC87058.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ356259-2|ABC87056.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ356258-2|ABC87054.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ356257-2|ABC87052.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ354391-2|ABC79055.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ354390-2|ABC79053.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ354389-2|ABC79051.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
DQ354388-2|ABC79049.1| 1663|Homo sapiens CTTNBP2 protein. 63 3e-09
CR457302-1|CAG33583.1| 278|Homo sapiens ASB13 protein. 63 3e-09
BC118585-1|AAI18586.1| 273|Homo sapiens ASB16 protein protein. 63 3e-09
BC118584-1|AAI18585.1| 273|Homo sapiens ASB16 protein protein. 63 3e-09
BC106000-1|AAI06001.1| 1663|Homo sapiens cortactin binding prote... 63 3e-09
AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 63 3e-09
AL512503-1|CAH72483.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 63 3e-09
AL365356-2|CAH72614.1| 278|Homo sapiens ankyrin repeat and SOCS... 63 3e-09
AL359752-4|CAI18974.1| 2471|Homo sapiens Notch homolog 2 (Drosop... 63 3e-09
AK027869-1|BAB55419.1| 773|Homo sapiens protein ( Homo sapiens ... 63 3e-09
AF377960-1|AAL32176.1| 1663|Homo sapiens cortactin-binding prote... 63 3e-09
AF315356-1|AAG37073.1| 2471|Homo sapiens NOTCH2 protein protein. 63 3e-09
AF308601-1|AAA36377.2| 2471|Homo sapiens NOTCH 2 protein. 63 3e-09
AB051545-1|BAB21849.1| 1662|Homo sapiens KIAA1758 protein protein. 63 3e-09
BC126351-1|AAI26352.1| 467|Homo sapiens ASB10 protein protein. 62 4e-09
BC013172-1|AAH13172.1| 294|Homo sapiens ankyrin repeat and SOCS... 62 4e-09
BC012056-1|AAH12056.1| 173|Homo sapiens ASB13 protein protein. 62 4e-09
AK125565-1|BAC86204.1| 452|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AK000643-1|BAA91302.1| 262|Homo sapiens protein ( Homo sapiens ... 62 4e-09
AF417920-1|AAL59159.1| 429|Homo sapiens ASB-10 protein. 62 4e-09
AF403031-1|AAL57350.1| 286|Homo sapiens ankyrin repeat domain-c... 62 4e-09
AB046856-1|BAB13462.2| 1864|Homo sapiens KIAA1636 protein protein. 62 4e-09
X61498-1|CAA43715.1| 933|Homo sapiens NF-kB subunit protein. 62 5e-09
S76638-1|AAB21124.1| 900|Homo sapiens p50-NF-kappa B homolog pr... 62 5e-09
BT009769-1|AAP88771.1| 899|Homo sapiens nuclear factor of kappa... 62 5e-09
BC002844-1|AAH02844.1| 899|Homo sapiens nuclear factor of kappa... 62 5e-09
AY865619-1|AAW56071.1| 900|Homo sapiens nuclear factor of kappa... 62 5e-09
AY557346-1|AAS67920.1| 273|Homo sapiens ankyrin repeat and SOCS... 62 5e-09
AL121928-1|CAC08399.1| 900|Homo sapiens nuclear factor of kappa... 62 5e-09
AL158217-11|CAI22163.1| 854|Homo sapiens espin protein. 62 6e-09
AL031848-3|CAI19773.1| 854|Homo sapiens espin protein. 62 6e-09
DQ508815-1|ABF60230.1| 593|Homo sapiens SARP protein. 61 8e-09
BC098394-1|AAH98394.1| 1327|Homo sapiens tankyrase, TRF1-interac... 61 8e-09
AL359707-2|CAC78760.1| 1166|Homo sapiens tankyrase, TRF1-interac... 61 8e-09
AL133620-1|CAB63746.1| 1031|Homo sapiens hypothetical protein pr... 61 8e-09
AF438201-1|AAL40795.1| 1166|Homo sapiens tankyrase II protein. 61 8e-09
AF342982-1|AAK25811.1| 1166|Homo sapiens tankyrase 2 protein. 61 8e-09
AF329696-1|AAK13463.1| 1166|Homo sapiens tankyrase 2 protein. 61 8e-09
AF309033-1|AAK82330.1| 1166|Homo sapiens tankyrase-2 protein. 61 8e-09
AF305081-1|AAG25674.1| 1265|Homo sapiens tankyrase-related prote... 61 8e-09
AF264912-1|AAG44694.1| 1166|Homo sapiens tankyrase-like protein ... 61 8e-09
AF082557-1|AAC79842.1| 1094|Homo sapiens TRF1-interacting ankyri... 61 8e-09
AF082556-1|AAC79841.1| 1327|Homo sapiens TRF1-interacting ankyri... 61 8e-09
AB209339-1|BAD92576.1| 1055|Homo sapiens tankyrase, TRF1-interac... 61 8e-09
DQ508934-1|ABF57994.1| 591|Homo sapiens SARP3 protein. 61 1e-08
BC022878-1|AAH22878.1| 776|Homo sapiens ankyrin repeat domain 5... 61 1e-08
AY462874-1|AAS58868.1| 508|Homo sapiens POTE14A protein. 61 1e-08
AL109754-1|CAB87618.2| 776|Homo sapiens ankyrin repeat domain 5... 61 1e-08
CR545463-1|CAM28350.1| 545|Homo sapiens protein expressed in pr... 60 1e-08
BC127623-1|AAI27624.1| 458|Homo sapiens ACTBL1 protein protein. 60 1e-08
BC127123-1|AAI27124.1| 581|Homo sapiens protein expressed in pr... 60 1e-08
BC112351-1|AAI12352.1| 725|Homo sapiens INVS protein protein. 60 1e-08
BC111761-1|AAI11762.1| 1065|Homo sapiens inversin, isoform a pro... 60 1e-08
BC107056-1|AAI07057.1| 305|Homo sapiens ankyrin repeat domain 2... 60 1e-08
BC101006-1|AAI01007.1| 581|Homo sapiens protein expressed in pr... 60 1e-08
BC101005-1|AAI01006.1| 544|Homo sapiens POTE15 protein protein. 60 1e-08
BC041665-1|AAH41665.1| 604|Homo sapiens Similar to inversin pro... 60 1e-08
AY465173-1|AAS58872.1| 581|Homo sapiens POTE15A protein. 60 1e-08
AY465172-1|AAS58871.1| 486|Homo sapiens POTE14C protein. 60 1e-08
AY465170-1|AAS58869.1| 544|Homo sapiens POTE15B protein. 60 1e-08
AY196212-1|AAO40750.1| 305|Homo sapiens muscle ankyrin repeat p... 60 1e-08
AL445214-4|CAI39744.1| 1065|Homo sapiens inversin protein. 60 1e-08
AL445214-3|CAI39745.2| 895|Homo sapiens inversin protein. 60 1e-08
AL356798-2|CAI40807.1| 1065|Homo sapiens inversin protein. 60 1e-08
AL356798-1|CAI40808.2| 895|Homo sapiens inversin protein. 60 1e-08
AL137072-3|CAH72173.1| 1065|Homo sapiens inversin protein. 60 1e-08
AL137072-2|CAM16212.1| 895|Homo sapiens inversin protein. 60 1e-08
AK092564-1|BAC03915.1| 263|Homo sapiens protein ( Homo sapiens ... 60 1e-08
AK057782-1|BAB71569.1| 268|Homo sapiens protein ( Homo sapiens ... 60 1e-08
AK023196-1|BAB14456.1| 278|Homo sapiens ARPP-19) mRNA. protein. 60 1e-08
AJ315766-1|CAC86120.1| 296|Homo sapiens Ankyrin repeat-containi... 60 1e-08
AF492401-1|AAO24067.1| 305|Homo sapiens diabetes related ankyri... 60 1e-08
AF084382-2|AAC79457.1| 895|Homo sapiens inversin protein altern... 60 1e-08
AF084382-1|AAC79456.1| 1065|Homo sapiens inversin protein protein. 60 1e-08
AF084367-1|AAC79436.1| 1065|Homo sapiens inversin protein protein. 60 1e-08
AC092636-3|AAY14965.1| 305|Homo sapiens unknown protein. 60 1e-08
BC101620-1|AAI01621.1| 1001|Homo sapiens ankyrin repeat domain 3... 60 2e-08
BC101618-1|AAI01619.1| 1001|Homo sapiens ankyrin repeat domain 3... 60 2e-08
AK091555-1|BAC03695.1| 505|Homo sapiens protein ( Homo sapiens ... 60 2e-08
BT006845-1|AAP35491.1| 528|Homo sapiens protein phosphatase 1, ... 60 2e-08
BC063609-1|AAH63609.1| 423|Homo sapiens NFKBIE protein protein. 60 2e-08
BC053506-1|AAH53506.1| 528|Homo sapiens protein phosphatase 1, ... 60 2e-08
BC049841-1|AAH49841.1| 528|Homo sapiens protein phosphatase 1, ... 60 2e-08
BC011676-1|AAH11676.2| 423|Homo sapiens NFKBIE protein protein. 60 2e-08
BC007854-1|AAH07854.1| 528|Homo sapiens protein phosphatase 1, ... 60 2e-08
AY462873-1|AAS58867.1| 376|Homo sapiens POTE2C protein. 60 2e-08
AY462871-1|AAS58865.1| 712|Homo sapiens POTE2A protein. 60 2e-08
AY462868-1|AAS58862.1| 376|Homo sapiens POTE2D protein. 60 2e-08
AL139392-10|CAI20103.1| 500|Homo sapiens nuclear factor of kapp... 60 2e-08
AK095193-1|BAC04496.1| 389|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AK091120-1|BAC03587.1| 1001|Homo sapiens protein ( Homo sapiens ... 60 2e-08
AF261937-1|AAM27002.1| 361|Homo sapiens NFKBIE protein protein. 60 2e-08
EF523384-1|ABP57734.1| 1075|Homo sapiens POTE-2 alpha-actin prot... 59 3e-08
BC113409-1|AAI13410.1| 1416|Homo sapiens uveal autoantigen with ... 59 3e-08
BC113407-1|AAI13408.1| 1416|Homo sapiens uveal autoantigen with ... 59 3e-08
BC069013-1|AAH69013.1| 457|Homo sapiens ANKRD11 protein protein. 59 3e-08
BC065710-1|AAH65710.1| 329|Homo sapiens ankyrin repeat and SOCS... 59 3e-08
BC016881-1|AAH16881.1| 638|Homo sapiens Unknown (protein for IM... 59 3e-08
AY533563-1|AAS45544.1| 2663|Homo sapiens ankyrin repeat-containi... 59 3e-08
AY373756-1|AAR25661.1| 2664|Homo sapiens ankyrin repeat-containi... 59 3e-08
AY057053-1|AAL18248.1| 329|Homo sapiens SOCS box protein ASB-5 ... 59 3e-08
AL080091-1|CAB45706.2| 266|Homo sapiens hypothetical protein pr... 59 3e-08
AK098693-1|BAC05382.1| 276|Homo sapiens protein ( Homo sapiens ... 59 3e-08
AK096441-1|BAC04791.1| 329|Homo sapiens protein ( Homo sapiens ... 59 3e-08
AK055435-1|BAB70922.1| 634|Homo sapiens protein ( Homo sapiens ... 59 3e-08
AF121775-1|AAF24125.1| 366|Homo sapiens nasopharyngeal carcinom... 59 3e-08
AF039217-1|AAD02131.2| 1013|Homo sapiens inv candidate homolog p... 59 3e-08
AB209186-1|BAD92423.1| 439|Homo sapiens ankyrin repeat domain 1... 59 3e-08
AB046781-1|BAB13387.2| 1416|Homo sapiens KIAA1561 protein protein. 59 3e-08
BC131801-1|AAI31802.1| 567|Homo sapiens protein phosphatase 1, ... 59 4e-08
AL121889-2|CAM27345.1| 467|Homo sapiens protein phosphatase 1, ... 59 4e-08
AL121889-1|CAI19080.1| 567|Homo sapiens protein phosphatase 1, ... 59 4e-08
AL031657-2|CAM28212.1| 467|Homo sapiens protein phosphatase 1, ... 59 4e-08
AL031657-1|CAI20058.1| 567|Homo sapiens protein phosphatase 1, ... 59 4e-08
AF362910-1|AAK52796.1| 567|Homo sapiens CAAX box protein TIMAP ... 59 4e-08
AB177855-1|BAD66833.1| 467|Homo sapiens KIAA0823 splice variant... 59 4e-08
AB020630-1|BAA74846.2| 578|Homo sapiens KIAA0823 protein protein. 59 4e-08
BC066909-1|AAH66909.1| 300|Homo sapiens ankyrin repeat domain 5... 58 6e-08
AK125596-1|BAC86214.1| 235|Homo sapiens protein ( Homo sapiens ... 58 6e-08
AK124559-1|BAC85884.1| 1005|Homo sapiens protein ( Homo sapiens ... 58 6e-08
AF451977-1|AAL49758.1| 1431|Homo sapiens cask-interacting protei... 58 6e-08
AB075861-1|BAB85567.1| 863|Homo sapiens KIAA1981 protein protein. 58 6e-08
AB033081-1|BAA86569.2| 1232|Homo sapiens KIAA1255 protein protein. 58 6e-08
EF041819-1|ABL09300.1| 782|Homo sapiens several ankyrin repeat ... 58 8e-08
AY172978-1|AAO23914.1| 584|Homo sapiens POTE protein. 58 8e-08
AL031177-2|CAI43133.1| 185|Homo sapiens proteasome (prosome, ma... 58 8e-08
BC066981-1|AAH66981.1| 381|Homo sapiens POTE15 protein protein. 58 1e-07
AY462869-1|AAS58863.1| 498|Homo sapiens POTE8A protein. 58 1e-07
BC130610-1|AAI30611.1| 1672|Homo sapiens KIDINS220 protein protein. 57 1e-07
BC066643-1|AAH66643.1| 1202|Homo sapiens CASK interacting protei... 57 1e-07
BC030622-1|AAH30622.1| 301|Homo sapiens ankyrin repeat domain 2... 57 1e-07
AF451976-1|AAL49757.1| 1202|Homo sapiens cask-interacting protei... 57 1e-07
AB033076-1|BAA86564.2| 1777|Homo sapiens KIAA1250 protein protein. 57 1e-07
Z97630-4|CAB63057.1| 300|Homo sapiens protein ( Human DNA seque... 57 2e-07
CR456471-1|CAG30357.1| 300|Homo sapiens dJ466N1.4 protein. 57 2e-07
BC017798-1|AAH17798.1| 239|Homo sapiens ankyrin repeat domain 4... 57 2e-07
BC014641-1|AAH14641.1| 300|Homo sapiens ankyrin repeat domain 5... 57 2e-07
AF025354-1|AAK60412.1| 239|Homo sapiens fetal globin-inducing f... 57 2e-07
AK000196-1|BAA91003.1| 239|Homo sapiens protein ( Homo sapiens ... 56 2e-07
BC004173-1|AAH04173.1| 1500|Homo sapiens ANKRD17 protein protein. 56 3e-07
AB014597-1|BAA31672.2| 2486|Homo sapiens KIAA0697 protein protein. 56 3e-07
BC024189-1|AAH24189.2| 345|Homo sapiens fibronectin type III an... 56 4e-07
AY358154-1|AAQ88521.1| 371|Homo sapiens CG3104 hlg protein. 56 4e-07
AL035288-1|CAA22892.1| 671|Homo sapiens hypothetical protein pr... 56 4e-07
AL021920-3|CAI19632.1| 671|Homo sapiens espin pseudogene protein. 56 4e-07
AK025859-1|BAB15260.1| 460|Homo sapiens protein ( Homo sapiens ... 56 4e-07
AB037360-1|BAA90300.1| 1166|Homo sapiens ANKHZN protein. 56 4e-07
D86982-1|BAA13218.1| 1180|Homo sapiens KIAA0229 protein. 55 7e-07
BX005460-4|CAM26150.1| 297|Homo sapiens euchromatic histone-lys... 55 7e-07
BC132832-1|AAI32833.1| 1134|Homo sapiens ankyrin repeat and ster... 55 7e-07
BC022396-1|AAH22396.1| 472|Homo sapiens Unknown (protein for IM... 55 7e-07
BC020817-1|AAH20817.2| 303|Homo sapiens ANKRD2 protein protein. 55 7e-07
AL671762-12|CAI18225.2| 297|Homo sapiens euchromatic histone-ly... 55 7e-07
AL662834-23|CAM24991.1| 297|Homo sapiens euchromatic histone-ly... 55 7e-07
AL591002-1|CAI15138.1| 1134|Homo sapiens ankyrin repeat and ster... 55 7e-07
AL359388-5|CAI14193.1| 300|Homo sapiens ankyrin repeat domain 2... 55 7e-07
AL355315-10|CAI15462.1| 300|Homo sapiens ankyrin repeat domain ... 55 7e-07
AL138721-1|CAI12437.1| 1134|Homo sapiens ankyrin repeat and ster... 55 7e-07
AL033520-2|CAI20281.1| 1134|Homo sapiens ankyrin repeat and ster... 55 7e-07
AK093479-1|BAC04181.1| 530|Homo sapiens protein ( Homo sapiens ... 55 7e-07
U91616-1|AAC51216.1| 500|Homo sapiens I kappa B epsilon protein. 54 9e-07
BC070234-1|AAH70234.1| 371|Homo sapiens ANKRD12 protein protein. 54 9e-07
BC057225-1|AAH57225.1| 330|Homo sapiens ANKRD12 protein protein. 54 9e-07
BC056152-1|AAH56152.1| 622|Homo sapiens zinc finger, DHHC-type ... 54 9e-07
BC036020-1|AAH36020.1| 622|Homo sapiens zinc finger, DHHC-type ... 54 9e-07
AY533564-1|AAS45545.2| 2039|Homo sapiens ankyrin repeat-containi... 54 9e-07
AY373757-1|AAR25662.1| 2062|Homo sapiens ankyrin repeat-containi... 54 9e-07
AK024808-1|BAB15014.1| 492|Homo sapiens protein ( Homo sapiens ... 54 9e-07
AK001714-1|BAA91856.1| 481|Homo sapiens protein ( Homo sapiens ... 54 9e-07
AF322916-1|AAG49577.1| 1416|Homo sapiens uveal autoantigen protein. 54 9e-07
AF317425-1|AAG38609.1| 2062|Homo sapiens GAC-1 protein. 54 9e-07
AB097027-1|BAC77380.1| 622|Homo sapiens putative MAPK activatin... 54 9e-07
AB097014-1|BAC77367.1| 622|Homo sapiens putative NFkB activatin... 54 9e-07
AB024495-1|BAC22090.1| 622|Homo sapiens huntingtin interacting ... 54 9e-07
D87930-1|BAA22378.1| 1030|Homo sapiens myosin phosphatase target... 54 1e-06
BC111752-1|AAI11753.1| 1030|Homo sapiens PPP1R12A protein protein. 54 1e-06
BC101007-1|AAI01008.1| 301|Homo sapiens POTE15 protein protein. 54 1e-06
BC092481-1|AAH92481.1| 730|Homo sapiens PPP1R12A protein protein. 54 1e-06
BC047898-1|AAH47898.1| 692|Homo sapiens PPP1R12A protein protein. 54 1e-06
BC035234-1|AAH35234.1| 343|Homo sapiens ankyrin repeat domain 5... 54 1e-06
AY380574-1|AAQ88438.1| 974|Homo sapiens myosin phosphatase targ... 54 1e-06
AF458589-1|AAM49717.1| 995|Homo sapiens myosin phosphatase targ... 54 1e-06
BC117678-1|AAI17679.1| 581|Homo sapiens ANKHD1 protein protein. 54 2e-06
BC004988-1|AAH04988.1| 669|Homo sapiens fem-1 homolog a (C. ele... 54 2e-06
AY356352-1|AAR10439.1| 669|Homo sapiens prostaglandin E recepto... 54 2e-06
AJ311359-1|CAC85342.1| 668|Homo sapiens putative sex determinin... 54 2e-06
AF403033-1|AAL57352.1| 434|Homo sapiens ankyrin repeat domain-c... 54 2e-06
BC022403-1|AAH22403.1| 395|Homo sapiens MIB1 protein protein. 53 2e-06
AY462872-1|AAS58866.1| 394|Homo sapiens POTE2B protein. 53 2e-06
AK098736-1|BAC05399.1| 181|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AK057011-1|BAB71342.1| 258|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AK000100-1|BAA90945.1| 420|Homo sapiens protein ( Homo sapiens ... 53 2e-06
AB037744-1|BAA92561.1| 396|Homo sapiens KIAA1323 protein protein. 53 2e-06
BC032799-1|AAH32799.1| 201|Homo sapiens ANKRD7 protein protein. 53 3e-06
BC009909-1|AAH09909.1| 627|Homo sapiens ankyrin repeat and KH d... 53 3e-06
BC028407-1|AAH28407.1| 619|Homo sapiens ankyrin repeat domain 3... 52 4e-06
D79994-1|BAA11489.2| 1366|Homo sapiens KIAA0172 protein. 52 5e-06
BC038116-1|AAH38116.1| 1194|Homo sapiens ankyrin repeat domain 1... 52 5e-06
BC037495-1|AAH37495.1| 1352|Homo sapiens ANKRD15 protein protein. 52 5e-06
BC020040-1|AAH20040.1| 784|Homo sapiens ANKRD15 protein protein. 52 5e-06
AY462870-1|AAS58864.1| 452|Homo sapiens POTE8B protein. 52 5e-06
AY281131-1|AAP37612.1| 1249|Homo sapiens AIDA-1b protein. 52 5e-06
AY070436-1|AAL65263.1| 968|Homo sapiens hypothetical protein pr... 52 5e-06
AY057056-1|AAL25260.1| 151|Homo sapiens hepatocellular carcinom... 52 5e-06
AL442128-2|CAH73039.1| 420|Homo sapiens ankyrin repeat domain 1... 52 5e-06
AL157875-2|CAH70238.1| 420|Homo sapiens ankyrin repeat domain 1... 52 5e-06
AL136979-5|CAH70389.1| 330|Homo sapiens ankyrin repeat domain 1... 52 5e-06
AL136979-4|CAM13084.1| 1194|Homo sapiens ankyrin repeat domain 1... 52 5e-06
AL136979-3|CAH70388.1| 1352|Homo sapiens ankyrin repeat domain 1... 52 5e-06
AL031177-6|CAI43131.1| 151|Homo sapiens proteasome (prosome, ma... 52 5e-06
AK074173-1|BAB84999.1| 1486|Homo sapiens FLJ00246 protein protein. 52 5e-06
AK000295-1|BAA91063.1| 686|Homo sapiens protein ( Homo sapiens ... 52 5e-06
AF521883-1|AAO14944.1| 2617|Homo sapiens multiple ankyrin repeat... 52 5e-06
AF521882-1|AAO14943.1| 2542|Homo sapiens multiple ankyrin repeat... 52 5e-06
AF217646-1|AAG41779.1| 532|Homo sapiens hypothetical protein pr... 52 5e-06
BC062346-1|AAH62346.1| 361|Homo sapiens ankyrin repeat domain 1... 52 7e-06
BC045621-1|AAH45621.1| 198|Homo sapiens ANKRD42 protein protein. 52 7e-06
AL137186-4|CAI41072.1| 361|Homo sapiens ankyrin repeat domain 1... 52 7e-06
U17074-1|AAC50074.1| 168|Homo sapiens p18 protein. 51 9e-06
CR450289-1|CAG29285.1| 168|Homo sapiens CDKN2C protein. 51 9e-06
BC113481-1|AAI13482.1| 349|Homo sapiens ankyrin repeat and SOCS... 51 9e-06
BC113479-1|AAI13480.1| 349|Homo sapiens ankyrin repeat and SOCS... 51 9e-06
BC028369-1|AAH28369.1| 617|Homo sapiens fem-1 homolog c (C. ele... 51 9e-06
BC025024-1|AAH25024.1| 318|Homo sapiens Unknown (protein for IM... 51 9e-06
BC016173-1|AAH16173.1| 168|Homo sapiens cyclin-dependent kinase... 51 9e-06
BC005041-1|AAH05041.1| 168|Homo sapiens cyclin-dependent kinase... 51 9e-06
BC000598-1|AAH00598.1| 168|Homo sapiens cyclin-dependent kinase... 51 9e-06
AY249188-1|AAO64429.1| 617|Homo sapiens FEM1C protein. 51 9e-06
AY094608-1|AAM11873.1| 168|Homo sapiens cyclin-dependent kinase... 51 9e-06
AL590455-1|CAH71955.1| 168|Homo sapiens cyclin-dependent kinase... 51 9e-06
AL390918-2|CAI15822.1| 940|Homo sapiens protein ( Human DNA seq... 51 9e-06
AL390918-1|CAI15821.1| 1858|Homo sapiens protein ( Human DNA seq... 51 9e-06
AL365415-1|CAB96957.1| 271|Homo sapiens similar to (NP_034322.1... 51 9e-06
AL359977-3|CAH70191.1| 168|Homo sapiens cyclin-dependent kinase... 51 9e-06
AL353143-2|CAH73222.1| 940|Homo sapiens protein ( Human DNA seq... 51 9e-06
AL353143-1|CAH73221.1| 1858|Homo sapiens protein ( Human DNA seq... 51 9e-06
AL161431-1|CAI15548.1| 1858|Homo sapiens protein ( Human DNA seq... 51 9e-06
AL157771-2|CAI16367.1| 940|Homo sapiens protein ( Human DNA seq... 51 9e-06
AL157771-1|CAI16366.1| 1858|Homo sapiens protein ( Human DNA seq... 51 9e-06
AL136979-6|CAH70390.1| 276|Homo sapiens ankyrin repeat domain 1... 51 9e-06
AL136132-2|CAH70520.1| 940|Homo sapiens protein ( Human DNA seq... 51 9e-06
AL136132-1|CAH70519.1| 1858|Homo sapiens protein ( Human DNA seq... 51 9e-06
AK127806-1|BAC87143.1| 935|Homo sapiens protein ( Homo sapiens ... 51 9e-06
AF391093-1|AAL37627.1| 617|Homo sapiens FEM1A protein. 51 9e-06
AF156779-1|AAD41896.1| 426|Homo sapiens ASB-4 protein protein. 51 9e-06
AF041250-1|AAC39783.1| 168|Homo sapiens cyclin-dependent kinase... 51 9e-06
AF041248-1|AAC39782.1| 168|Homo sapiens cyclin-dependent kinase... 51 9e-06
AC007874-1|AAF19231.1| 131|Homo sapiens WUGSC:H_DJ1035O02.1 pro... 51 9e-06
AC003079-1|AAB83943.2| 426|Homo sapiens unknown protein. 51 9e-06
AB058688-1|BAB47414.1| 617|Homo sapiens KIAA1785 protein protein. 51 9e-06
AB020672-1|BAA74888.2| 1900|Homo sapiens KIAA0865 protein protein. 51 9e-06
BC128517-1|AAI28518.1| 309|Homo sapiens ANKRD36 protein protein. 51 1e-05
BC128262-1|AAI28263.1| 346|Homo sapiens ANKRD36 protein protein. 51 1e-05
BC127127-1|AAI27128.1| 627|Homo sapiens ankyrin repeat and KH d... 51 1e-05
BC117677-1|AAI17678.1| 627|Homo sapiens ankyrin repeat and KH d... 51 1e-05
BC009420-1|AAH09420.1| 616|Homo sapiens ankyrin repeat and KH d... 51 1e-05
>DQ152234-1|AAZ77790.1| 707|Homo sapiens Shank2E protein.
Length = 707
Score = 392 bits (964), Expect = e-108
Identities = 186/320 (58%), Positives = 232/320 (72%), Gaps = 6/320 (1%)
Query: 1 MCVLKNELKESFNYGLFCPPVNGKAGKFLDEERRLGDYPFNGPVGY----LELKYKRRVY 56
+C L LK+ NYGLF P NG+ GKFLDEER L +YP PVG LE +YK+RVY
Sbjct: 88 LCTLTQSLKDVLNYGLFQPASNGRDGKFLDEERLLREYP--QPVGEGVPSLEFRYKKRVY 145
Query: 57 KMLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAA 116
K LDEK L LH++ NL++ ++H+ H ++KITK +GLDPNFH ETGETPLT+AA
Sbjct: 146 KQASLDEKQLAKLHTKTNLKKCMDHIQHRLVEKITKMLDRGLDPNFHDPETGETPLTLAA 205
Query: 117 GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGL 176
L +++ AL NGGA LD+R +DG TA+H+A + A+KTLLELGASP+YKD GL
Sbjct: 206 QLDDSVEVIKALKNGGAHLDFRAKDGMTALHKAARARNQVALKTLLELGASPDYKDSYGL 265
Query: 177 TPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMN 236
TPLY + DP CE LLH+HAT+ D GW E+HQACR G VQH++HLLFYGADM+
Sbjct: 266 TPLYHTAIVGGDPYCCELLLHEHATVCCKDENGWHEIHQACRYGHVQHLEHLLFYGADMS 325
Query: 237 ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
A+NASGNT LH+CA+ QDSCAR LLFRG +KE N+ +QTP+QVA+IAGN +LAE IKN
Sbjct: 326 AQNASGNTALHICALYNQDSCARVLLFRGGNKELKNYNSQTPFQVAIIAGNFELAEYIKN 385
Query: 297 YKSDEIVPFRGPPRYNPRRR 316
+K +IVPFR P Y+ RRR
Sbjct: 386 HKETDIVPFREAPAYSNRRR 405
Score = 48.0 bits (109), Expect = 8e-05
Identities = 24/65 (36%), Positives = 36/65 (55%), Gaps = 2/65 (3%)
Query: 417 SLQPSSTAVCLQPYEGAAPGHLRLNQGDIVEVTAASDDGLLEGCVRGSGAAGLFPAHCVQ 476
S P V ++PY+ G + L++GD V+V + + G EG RG G FPA CV+
Sbjct: 524 SAVPGRLFVAVKPYQPQVDGEIPLHRGDRVKVLSIGEGGFWEGSARGH--IGWFPAECVE 581
Query: 477 EVRLR 481
EV+ +
Sbjct: 582 EVQCK 586
>AF163302-1|AAD45121.1| 2161|Homo sapiens somatostatin receptor
interacting protein splice variant a protein.
Length = 2161
Score = 344 bits (846), Expect = 4e-94
Identities = 159/318 (50%), Positives = 216/318 (67%), Gaps = 2/318 (0%)
Query: 1 MCVLKNELKESFNYGLFCPPVNGKAGKFLDEERRLGDYP--FNGPVGYLELKYKRRVYKM 58
+C L L++ NYGLF P +G+ FL+EER L +YP F V YLE +YK RVYK
Sbjct: 104 LCALSESLQDVLNYGLFQPATSGRDANFLEEERLLREYPQSFEKGVPYLEFRYKTRVYKQ 163
Query: 59 LKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGL 118
LDEK L LH++ L++FLE+V G DK+ + KGLDPN+H ++GETPLT+AA
Sbjct: 164 TNLDEKQLAKLHTKTGLKKFLEYVQLGTSDKVARLLDKGLDPNYHDSDSGETPLTLAAQT 223
Query: 119 KSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTP 178
+ +++ L GGA +D+R RDG TA+H+A A+ LL+LG SPNYKD +GLTP
Sbjct: 224 EGSVEVIRTLCLGGAHIDFRARDGMTALHKAACARHCLALTALLDLGGSPNYKDRRGLTP 283
Query: 179 LYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
L+ + DP CE LL + A +G D GWQE+HQAC+ G QH++HLLFYGA+ A+
Sbjct: 284 LFHTAMVGGDPRCCELLLFNRAQLGIADENGWQEIHQACQRGHSQHLEHLLFYGAEPGAQ 343
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYK 298
NASGNT LH+CA+ +++CAR LL+RG DK+ N QTP+QVAVIAGN +L E+I+N++
Sbjct: 344 NASGNTALHICALYNKETCARILLYRGADKDVKNNNGQTPFQVAVIAGNFELGELIRNHR 403
Query: 299 SDEIVPFRGPPRYNPRRR 316
++VPF+ P+Y RRR
Sbjct: 404 EQDVVPFQESPKYAARRR 421
Score = 41.9 bits (94), Expect = 0.005
Identities = 20/65 (30%), Positives = 37/65 (56%), Gaps = 2/65 (3%)
Query: 417 SLQPSSTAVCLQPYEGAAPGHLRLNQGDIVEVTAASDDGLLEGCVRGSGAAGLFPAHCVQ 476
S P + + ++ Y+ A G + L++G+ ++V + + G EG V+G G FP+ C++
Sbjct: 552 SAVPGRSFMAVKSYQAQAEGEISLSKGEKIKVLSIGEGGFWEGQVKGR--VGWFPSDCLE 609
Query: 477 EVRLR 481
EV R
Sbjct: 610 EVANR 614
>AJ541797-1|CAD62569.2| 765|Homo sapiens ankyrin repeat and kinase
domain containing 1 protein.
Length = 765
Score = 93.9 bits (223), Expect = 1e-18
Identities = 62/185 (33%), Positives = 96/185 (51%), Gaps = 3/185 (1%)
Query: 99 DPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
DPN H E G+TPL +AA + + + L + GA LD + R+ T +H AVE+ + A+
Sbjct: 486 DPNLHEAE-GKTPLHVAAYFGHVSLVKL-LTSQGAELDAQQRNLRTPLHLAVERGKVRAI 543
Query: 159 KTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACR 218
+ LL+ GA P+ D G PL+ + + L+C+ LL A++ QGW +H A
Sbjct: 544 QHLLKSGAVPDALDQSGYGPLHTAAA-RGKYLICKMLLRYGASLELPTHQGWTPLHLAAY 602
Query: 219 NGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
G ++ + L A+M A A TPLH+ A + +++ LL G D A + TP
Sbjct: 603 KGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTP 662
Query: 279 YQVAV 283
+AV
Sbjct: 663 LHLAV 667
Score = 79.8 bits (188), Expect = 2e-14
Identities = 58/190 (30%), Positives = 82/190 (43%), Gaps = 2/190 (1%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL 164
Q TPL +A + + + L+ GA+ D + G +H A + K LL
Sbjct: 524 QRNLRTPLHLAVE-RGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRY 582
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
GAS +G TPL+L+ K + L HA +GA W +H A R+G
Sbjct: 583 GASLELPTHQGWTPLHLAAY-KGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAV 641
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
V LL GAD NA SG TPLH+ + LL + A N TP +A +
Sbjct: 642 VSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAAL 701
Query: 285 AGNLDLAEVI 294
GN + +V+
Sbjct: 702 KGNTAILKVL 711
Score = 76.2 bits (179), Expect = 3e-13
Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 1/151 (0%)
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H V + S+E V+ LL + + G TPL ++ ++ P LC LL A
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQ-QPDLCALLLAHGADAN 422
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D GW +H A +NG LL +GA ++A+ G TPLH+ A N ++ AR L+
Sbjct: 423 RVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVS 482
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
R D +TP VA G++ L +++
Sbjct: 483 RQADPNLHEAEGKTPLHVAAYFGHVSLVKLL 513
Score = 73.3 bits (172), Expect = 2e-12
Identities = 60/211 (28%), Positives = 95/211 (45%), Gaps = 4/211 (1%)
Query: 74 NLRRFLE-HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGG 132
NLR L V G++ I G P+ ++G PL AA + I L+ G
Sbjct: 526 NLRTPLHLAVERGKVRAIQHLLKSGAVPDA-LDQSGYGPLHTAAA-RGKYLICKMLLRYG 583
Query: 133 ALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLC 192
A L+ T G T +H A K LE + L E A+ TPL+L+ + + ++
Sbjct: 584 ASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVV- 642
Query: 193 ETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVN 252
LL A A + GW +H A + V +LL + A+++ARN G TP H+ A+
Sbjct: 643 SALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALK 702
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ + L+ G + + + TP Q+A+
Sbjct: 703 GNTAILKVLVEAGAQLDVQDGVSCTPLQLAL 733
Score = 70.5 bits (165), Expect = 1e-11
Identities = 57/224 (25%), Positives = 101/224 (45%), Gaps = 5/224 (2%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQE-TGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
V G ++++ A +D + CQ +G TPL IAA + P + L +G A +
Sbjct: 370 VAQGSVEQVRLLLAHEVDVD--CQTASGYTPLLIAAQDQQPDLCALLLAHG-ADANRVDE 426
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
DG +H A + + LL+ GA + ++ +G TPL+L+ N + + L+ A
Sbjct: 427 DGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENV-ARLLVSRQA 485
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ +G +H A G V V L GA+++A+ + TPLH+ + +
Sbjct: 486 DPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQH 545
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
LL G +AL+ + P A G + +++ Y + +P
Sbjct: 546 LLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELP 589
Score = 68.9 bits (161), Expect = 4e-11
Identities = 54/184 (29%), Positives = 78/184 (42%), Gaps = 4/184 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E TPL S ++ + L + +D +T G T + A + + LL G
Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHE-VDVDCQTASGYTPLLIAAQDQQPDLCALLLAHG 418
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQH 224
A N D G PL+ + N D LL DH A + A + +GW +H A +N
Sbjct: 419 ADANRVDEDGWAPLHFAAQNGDDGTA--RLLLDHGACVDAQEREGWTPLHLAAQNNFENV 476
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
L+ AD N A G TPLHV A S + L +G + +A +TP +AV
Sbjct: 477 ARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVE 536
Query: 285 AGNL 288
G +
Sbjct: 537 RGKV 540
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 2/108 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG+ ++ G DPN +++G TPL +A +S +I L+ A + R + G
Sbjct: 636 HGEEAVVSALLQCGADPNA-AEQSGWTPLHLAVQ-RSTFLSVINLLEHHANVHARNKVGW 693
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLL 191
T H A K + +K L+E GA + +DG TPL L++ ++ ++
Sbjct: 694 TPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIM 741
Score = 36.7 bits (81), Expect = 0.20
Identities = 23/85 (27%), Positives = 38/85 (44%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H G V+ V LL + D++ + ASG TPL + A + Q LL G D ++
Sbjct: 366 LHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVD 425
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNY 297
P A G+ A ++ ++
Sbjct: 426 EDGWAPLHFAAQNGDDGTARLLLDH 450
>AF525298-1|AAM91924.1| 765|Homo sapiens X-kinase protein.
Length = 765
Score = 93.9 bits (223), Expect = 1e-18
Identities = 62/185 (33%), Positives = 96/185 (51%), Gaps = 3/185 (1%)
Query: 99 DPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
DPN H E G+TPL +AA + + + L + GA LD + R+ T +H AVE+ + A+
Sbjct: 486 DPNLHEAE-GKTPLHVAAYFGHVSLVKL-LTSQGAELDAQQRNLRTPLHLAVERGKVRAI 543
Query: 159 KTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACR 218
+ LL+ GA P+ D G PL+ + + L+C+ LL A++ QGW +H A
Sbjct: 544 QHLLKSGAVPDALDQSGYGPLHTAAA-RGKYLICKMLLRYGASLELPTHQGWTPLHLAAY 602
Query: 219 NGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
G ++ + L A+M A A TPLH+ A + +++ LL G D A + TP
Sbjct: 603 KGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTP 662
Query: 279 YQVAV 283
+AV
Sbjct: 663 LHLAV 667
Score = 79.8 bits (188), Expect = 2e-14
Identities = 58/190 (30%), Positives = 82/190 (43%), Gaps = 2/190 (1%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL 164
Q TPL +A + + + L+ GA+ D + G +H A + K LL
Sbjct: 524 QRNLRTPLHLAVE-RGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRY 582
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
GAS +G TPL+L+ K + L HA +GA W +H A R+G
Sbjct: 583 GASLELPTHQGWTPLHLAAY-KGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAV 641
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
V LL GAD NA SG TPLH+ + LL + A N TP +A +
Sbjct: 642 VSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAAL 701
Query: 285 AGNLDLAEVI 294
GN + +V+
Sbjct: 702 KGNTAILKVL 711
Score = 76.2 bits (179), Expect = 3e-13
Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 1/151 (0%)
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H V + S+E V+ LL + + G TPL ++ ++ P LC LL A
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQ-QPDLCALLLAHGADAN 422
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D GW +H A +NG LL +GA ++A+ G TPLH+ A N ++ AR L+
Sbjct: 423 RVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVS 482
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
R D +TP VA G++ L +++
Sbjct: 483 RQADPNLHEAEGKTPLHVAAYFGHVSLVKLL 513
Score = 73.3 bits (172), Expect = 2e-12
Identities = 60/211 (28%), Positives = 95/211 (45%), Gaps = 4/211 (1%)
Query: 74 NLRRFLE-HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGG 132
NLR L V G++ I G P+ ++G PL AA + I L+ G
Sbjct: 526 NLRTPLHLAVERGKVRAIQHLLKSGAVPDA-LDQSGYGPLHTAAA-RGKYLICKMLLRYG 583
Query: 133 ALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLC 192
A L+ T G T +H A K LE + L E A+ TPL+L+ + + ++
Sbjct: 584 ASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVV- 642
Query: 193 ETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVN 252
LL A A + GW +H A + V +LL + A+++ARN G TP H+ A+
Sbjct: 643 SALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALK 702
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ + L+ G + + + TP Q+A+
Sbjct: 703 GNTAILKVLVEAGAQLDVQDGVSCTPLQLAL 733
Score = 70.5 bits (165), Expect = 1e-11
Identities = 57/224 (25%), Positives = 101/224 (45%), Gaps = 5/224 (2%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQE-TGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
V G ++++ A +D + CQ +G TPL IAA + P + L +G A +
Sbjct: 370 VAQGSVEQVRLLLAHEVDVD--CQTASGYTPLLIAAQDQQPDLCALLLAHG-ADANRVDE 426
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
DG +H A + + LL+ GA + ++ +G TPL+L+ N + + L+ A
Sbjct: 427 DGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENV-ARLLVSRQA 485
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ +G +H A G V V L GA+++A+ + TPLH+ + +
Sbjct: 486 DPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQH 545
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
LL G +AL+ + P A G + +++ Y + +P
Sbjct: 546 LLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELP 589
Score = 68.9 bits (161), Expect = 4e-11
Identities = 54/184 (29%), Positives = 78/184 (42%), Gaps = 4/184 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E TPL S ++ + L + +D +T G T + A + + LL G
Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHE-VDVDCQTASGYTPLLIAAQDQQPDLCALLLAHG 418
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQH 224
A N D G PL+ + N D LL DH A + A + +GW +H A +N
Sbjct: 419 ADANRVDEDGWAPLHFAAQNGDDGTA--RLLLDHGACVDAQEREGWTPLHLAAQNNFENV 476
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
L+ AD N A G TPLHV A S + L +G + +A +TP +AV
Sbjct: 477 ARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVE 536
Query: 285 AGNL 288
G +
Sbjct: 537 RGKV 540
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 2/108 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG+ ++ G DPN +++G TPL +A +S +I L+ A + R + G
Sbjct: 636 HGEEAVVSALLQCGADPNA-AEQSGWTPLHLAVQ-RSTFLSVINLLEHHANVHARNKVGW 693
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLL 191
T H A K + +K L+E GA + +DG TPL L++ ++ ++
Sbjct: 694 TPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIM 741
Score = 36.7 bits (81), Expect = 0.20
Identities = 23/85 (27%), Positives = 38/85 (44%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H G V+ V LL + D++ + ASG TPL + A + Q LL G D ++
Sbjct: 366 LHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVD 425
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNY 297
P A G+ A ++ ++
Sbjct: 426 EDGWAPLHFAAQNGDDGTARLLLDH 450
>AF487542-1|AAQ09005.1| 765|Homo sapiens protein kinase PKK2
protein.
Length = 765
Score = 93.9 bits (223), Expect = 1e-18
Identities = 62/185 (33%), Positives = 96/185 (51%), Gaps = 3/185 (1%)
Query: 99 DPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
DPN H E G+TPL +AA + + + L + GA LD + R+ T +H AVE+ + A+
Sbjct: 486 DPNLHEAE-GKTPLHVAAYFGHVSLVKL-LTSQGAELDAQQRNLRTPLHLAVERGKVRAI 543
Query: 159 KTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACR 218
+ LL+ GA P+ D G PL+ + + L+C+ LL A++ QGW +H A
Sbjct: 544 QHLLKSGAVPDALDQSGYGPLHTAAA-RGKYLICKMLLRYGASLELPTHQGWTPLHLAAY 602
Query: 219 NGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
G ++ + L A+M A A TPLH+ A + +++ LL G D A + TP
Sbjct: 603 KGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVVSALLQCGADPNAAEQSGWTP 662
Query: 279 YQVAV 283
+AV
Sbjct: 663 LHLAV 667
Score = 79.8 bits (188), Expect = 2e-14
Identities = 58/190 (30%), Positives = 82/190 (43%), Gaps = 2/190 (1%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL 164
Q TPL +A + + + L+ GA+ D + G +H A + K LL
Sbjct: 524 QRNLRTPLHLAVE-RGKVRAIQHLLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRY 582
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
GAS +G TPL+L+ K + L HA +GA W +H A R+G
Sbjct: 583 GASLELPTHQGWTPLHLAAY-KGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAV 641
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
V LL GAD NA SG TPLH+ + LL + A N TP +A +
Sbjct: 642 VSALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAAL 701
Query: 285 AGNLDLAEVI 294
GN + +V+
Sbjct: 702 KGNTAILKVL 711
Score = 76.2 bits (179), Expect = 3e-13
Identities = 48/151 (31%), Positives = 74/151 (49%), Gaps = 1/151 (0%)
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H V + S+E V+ LL + + G TPL ++ ++ P LC LL A
Sbjct: 364 TPLHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQ-QPDLCALLLAHGADAN 422
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D GW +H A +NG LL +GA ++A+ G TPLH+ A N ++ AR L+
Sbjct: 423 RVDEDGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENVARLLVS 482
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
R D +TP VA G++ L +++
Sbjct: 483 RQADPNLHEAEGKTPLHVAAYFGHVSLVKLL 513
Score = 73.3 bits (172), Expect = 2e-12
Identities = 60/211 (28%), Positives = 95/211 (45%), Gaps = 4/211 (1%)
Query: 74 NLRRFLE-HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGG 132
NLR L V G++ I G P+ ++G PL AA + I L+ G
Sbjct: 526 NLRTPLHLAVERGKVRAIQHLLKSGAVPDA-LDQSGYGPLHTAAA-RGKYLICKMLLRYG 583
Query: 133 ALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLC 192
A L+ T G T +H A K LE + L E A+ TPL+L+ + + ++
Sbjct: 584 ASLELPTHQGWTPLHLAAYKGHLEIIHLLAESHANMGALGAVNWTPLHLAARHGEEAVV- 642
Query: 193 ETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVN 252
LL A A + GW +H A + V +LL + A+++ARN G TP H+ A+
Sbjct: 643 SALLQCGADPNAAEQSGWTPLHLAVQRSTFLSVINLLEHHANVHARNKVGWTPAHLAALK 702
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ + L+ G + + + TP Q+A+
Sbjct: 703 GNTAILKVLVEAGAQLDVQDGVSCTPLQLAL 733
Score = 70.5 bits (165), Expect = 1e-11
Identities = 57/224 (25%), Positives = 101/224 (45%), Gaps = 5/224 (2%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQE-TGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
V G ++++ A +D + CQ +G TPL IAA + P + L +G A +
Sbjct: 370 VAQGSVEQVRLLLAHEVDVD--CQTASGYTPLLIAAQDQQPDLCALLLAHG-ADANRVDE 426
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
DG +H A + + LL+ GA + ++ +G TPL+L+ N + + L+ A
Sbjct: 427 DGWAPLHFAAQNGDDGTARLLLDHGACVDAQEREGWTPLHLAAQNNFENV-ARLLVSRQA 485
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ +G +H A G V V L GA+++A+ + TPLH+ + +
Sbjct: 486 DPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVERGKVRAIQH 545
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
LL G +AL+ + P A G + +++ Y + +P
Sbjct: 546 LLKSGAVPDALDQSGYGPLHTAAARGKYLICKMLLRYGASLELP 589
Score = 68.9 bits (161), Expect = 4e-11
Identities = 54/184 (29%), Positives = 78/184 (42%), Gaps = 4/184 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E TPL S ++ + L + +D +T G T + A + + LL G
Sbjct: 360 ENKVTPLHFLVAQGSVEQVRLLLAHE-VDVDCQTASGYTPLLIAAQDQQPDLCALLLAHG 418
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQH 224
A N D G PL+ + N D LL DH A + A + +GW +H A +N
Sbjct: 419 ADANRVDEDGWAPLHFAAQNGDDGTA--RLLLDHGACVDAQEREGWTPLHLAAQNNFENV 476
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
L+ AD N A G TPLHV A S + L +G + +A +TP +AV
Sbjct: 477 ARLLVSRQADPNLHEAEGKTPLHVAAYFGHVSLVKLLTSQGAELDAQQRNLRTPLHLAVE 536
Query: 285 AGNL 288
G +
Sbjct: 537 RGKV 540
Score = 48.4 bits (110), Expect = 6e-05
Identities = 32/108 (29%), Positives = 55/108 (50%), Gaps = 2/108 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG+ ++ G DPN +++G TPL +A +S +I L+ A + R + G
Sbjct: 636 HGEEAVVSALLQCGADPNA-AEQSGWTPLHLAVQ-RSTFLSVINLLEHHANVHARNKVGW 693
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLL 191
T H A K + +K L+E GA + +DG TPL L++ ++ ++
Sbjct: 694 TPAHLAALKGNTAILKVLVEAGAQLDVQDGVSCTPLQLALRSRKQGIM 741
Score = 36.7 bits (81), Expect = 0.20
Identities = 23/85 (27%), Positives = 38/85 (44%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H G V+ V LL + D++ + ASG TPL + A + Q LL G D ++
Sbjct: 366 LHFLVAQGSVEQVRLLLAHEVDVDCQTASGYTPLLIAAQDQQPDLCALLLAHGADANRVD 425
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNY 297
P A G+ A ++ ++
Sbjct: 426 EDGWAPLHFAAQNGDDGTARLLLDH 450
>U43965-1|AAB08437.1| 1088|Homo sapiens ankyrin G119 protein.
Length = 1088
Score = 93.5 bits (222), Expect = 2e-18
Identities = 64/216 (29%), Positives = 101/216 (46%), Gaps = 3/216 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ +++ G PN GET L +AA A+++ LV GA ++ + +D T
Sbjct: 65 GHVNIVSQLMHHGASPNT-TNVRGETALHMAAR-SGQAEVVRYLVQDGAQVEAKAKDDQT 122
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+H + + V+ LL+ GASPN G TPL+LS + + L H A++
Sbjct: 123 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG-ASLSI 181
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T +G+ +H A + G ++ + LL A +A SG TPLHV A A LL +
Sbjct: 182 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 241
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G A TP +A +D+A + Y +D
Sbjct: 242 GASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGAD 277
Score = 81.8 bits (193), Expect = 5e-15
Identities = 55/190 (28%), Positives = 88/190 (46%), Gaps = 2/190 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G TPL IAA K+ I L+ GA + TR G ++H A ++ ++ V LL
Sbjct: 250 KNGYTPLHIAAK-KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRN 308
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A+ N + GLTPL+L+ + + E L++ A + A G+ +H C G ++ V
Sbjct: 309 ANVNLSNKSGLTPLHLAA-QEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIV 367
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+ LL + A +NA+ +G TPLH A LL L T +A
Sbjct: 368 NFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRL 427
Query: 286 GNLDLAEVIK 295
G + + + +K
Sbjct: 428 GYISVVDTLK 437
Score = 80.2 bits (189), Expect = 2e-14
Identities = 58/192 (30%), Positives = 87/192 (45%), Gaps = 2/192 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A D + G T +H A ++ + LL+ GAS
Sbjct: 186 GFTPLHVAAKY-GKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGAS 244
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ K + TLL A A QG VH A + G V V
Sbjct: 245 PHAAAKNGYTPLHIAA-KKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSL 303
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A++N N SG TPLH+ A + + A L+ +G +A TP V GN
Sbjct: 304 LLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN 363
Query: 288 LDLAEVIKNYKS 299
+ + + + +
Sbjct: 364 IKIVNFLLQHSA 375
Score = 79.0 bits (186), Expect = 4e-14
Identities = 58/187 (31%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL IA K+ K++ L+ GA + T G T +H A + V L+ GAS
Sbjct: 21 GFTPLHIACK-KNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 79
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
PN + +G T L+++ + ++ L+ D A + A +H + R G V
Sbjct: 80 PNTTNVRGETALHMAARSGQAEVV-RYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 138
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL GA NA SG TPLH+ A + A LL G TP VA G
Sbjct: 139 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 198
Query: 288 LDLAEVI 294
L++A ++
Sbjct: 199 LEVANLL 205
Score = 75.4 bits (177), Expect = 5e-13
Identities = 44/157 (28%), Positives = 83/157 (52%), Gaps = 1/157 (0%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
+G T +H A +KN ++ ++ LL+ GAS GLTP++++ ++ + L+H A
Sbjct: 20 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQ-LMHHGA 78
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ T+++G +H A R+G + V +L+ GA + A+ TPLH+ A + +Q
Sbjct: 79 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 138
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
LL +G A + TP ++ G+ D+A + ++
Sbjct: 139 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDH 175
Score = 68.1 bits (159), Expect = 7e-11
Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Query: 161 LLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG 220
LL+ A+PN K G TPL+++ K + E LL A+I A G +H A G
Sbjct: 7 LLDKKANPNAKALNGFTPLHIAC-KKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMG 65
Query: 221 LVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQ 280
V V L+ +GA N N G T LH+ A + Q R L+ G EA +QTP
Sbjct: 66 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 125
Query: 281 VAVIAGNLDLAE 292
++ G D+ +
Sbjct: 126 ISARLGKADIVQ 137
Score = 53.2 bits (122), Expect = 2e-06
Identities = 34/111 (30%), Positives = 52/111 (46%), Gaps = 4/111 (3%)
Query: 190 LLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVC 249
L C+ LL A A L G+ +H AC+ ++ ++ LL +GA + A SG TP+HV
Sbjct: 3 LRCD-LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVA 61
Query: 250 AVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + QL+ G N +T +A +G AEV++ D
Sbjct: 62 AFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQ---AEVVRYLVQD 109
>U13616-1|AAA64834.1| 4377|Homo sapiens ankyrin G protein.
Length = 4377
Score = 93.5 bits (222), Expect = 2e-18
Identities = 64/216 (29%), Positives = 101/216 (46%), Gaps = 3/216 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ +++ G PN GET L +AA A+++ LV GA ++ + +D T
Sbjct: 444 GHVNIVSQLMHHGASPNT-TNVRGETALHMAAR-SGQAEVVRYLVQDGAQVEAKAKDDQT 501
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+H + + V+ LL+ GASPN G TPL+LS + + L H A++
Sbjct: 502 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG-ASLSI 560
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T +G+ +H A + G ++ + LL A +A SG TPLHV A A LL +
Sbjct: 561 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 620
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G A TP +A +D+A + Y +D
Sbjct: 621 GASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGAD 656
Score = 81.8 bits (193), Expect = 5e-15
Identities = 55/190 (28%), Positives = 88/190 (46%), Gaps = 2/190 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G TPL IAA K+ I L+ GA + TR G ++H A ++ ++ V LL
Sbjct: 629 KNGYTPLHIAAK-KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRN 687
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A+ N + GLTPL+L+ + + E L++ A + A G+ +H C G ++ V
Sbjct: 688 ANVNLSNKSGLTPLHLAA-QEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIV 746
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+ LL + A +NA+ +G TPLH A LL L T +A
Sbjct: 747 NFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRL 806
Query: 286 GNLDLAEVIK 295
G + + + +K
Sbjct: 807 GYISVVDTLK 816
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/214 (29%), Positives = 94/214 (43%), Gaps = 5/214 (2%)
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
H H ++ K+ K +PN G TPL IA K+ K++ L+ GA + T
Sbjct: 376 HCGHYKVAKVL--LDKKANPNAKALN-GFTPLHIACK-KNRIKVMELLLKHGASIQAVTE 431
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
G T +H A + V L+ GASPN + +G T L+++ + ++ L+ D A
Sbjct: 432 SGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVV-RYLVQDGA 490
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ A +H + R G V LL GA NA SG TPLH+ A + A
Sbjct: 491 QVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 550
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL G TP VA G L++A ++
Sbjct: 551 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 80.2 bits (189), Expect = 2e-14
Identities = 58/192 (30%), Positives = 87/192 (45%), Gaps = 2/192 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A D + G T +H A ++ + LL+ GAS
Sbjct: 565 GFTPLHVAAKY-GKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGAS 623
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ K + TLL A A QG VH A + G V V
Sbjct: 624 PHAAAKNGYTPLHIAA-KKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSL 682
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A++N N SG TPLH+ A + + A L+ +G +A TP V GN
Sbjct: 683 LLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN 742
Query: 288 LDLAEVIKNYKS 299
+ + + + +
Sbjct: 743 IKIVNFLLQHSA 754
Score = 79.4 bits (187), Expect = 3e-14
Identities = 52/158 (32%), Positives = 73/158 (46%), Gaps = 1/158 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D T D TA+H A + K LL+ A+PN K G TPL+++ K + E
Sbjct: 360 VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIAC-KKNRIKVMEL 418
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL A+I A G +H A G V V L+ +GA N N G T LH+ A + Q
Sbjct: 419 LLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQ 478
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAE 292
R L+ G EA +QTP ++ G D+ +
Sbjct: 479 AEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQ 516
Score = 76.6 bits (180), Expect = 2e-13
Identities = 47/175 (26%), Positives = 91/175 (52%), Gaps = 1/175 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
K+ L++ A + + +G T +H A +KN ++ ++ LL+ GAS GLTP++++
Sbjct: 381 KVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVA 440
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
++ + L+H A+ T+++G +H A R+G + V +L+ GA + A+
Sbjct: 441 AFMGHVNIVSQ-LMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 499
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
TPLH+ A + +QLL +G A + TP ++ G+ D+A + ++
Sbjct: 500 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDH 554
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/187 (29%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IA+ L A+++ LV GA ++ ++++G T ++ A ++N LE VK LL+ GAS
Sbjct: 107 GNTALHIAS-LAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGAS 165
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ G TPL +++ D ++ +LL ++ T G L +H A R +
Sbjct: 166 QSLATEDGFTPLAVALQQGHDQVV--SLLLENDTKGKVRLPA---LHIAARKDDTKAAAL 220
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL + + + SG TPLH+ A + A LL R + + TP VA GN
Sbjct: 221 LLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGN 280
Query: 288 LDLAEVI 294
++ +++
Sbjct: 281 ANMVKLL 287
Score = 70.1 bits (164), Expect = 2e-11
Identities = 53/190 (27%), Positives = 89/190 (46%), Gaps = 6/190 (3%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL +A+ + A ++ L++ GA +D +TRDG T +H + V+ LL+ A
Sbjct: 270 TPLHVASK-RGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPIL 328
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQG--WQEVHQACRNGLVQHVDH 227
K GL+PL+++ D L C LL H + D+ +H A G +
Sbjct: 329 SKTKNGLSPLHMATQG--DHLNCVQLLLQH-NVPVDDVTNDYLTALHVAAHCGHYKVAKV 385
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A+ NA+ +G TPLH+ + LL G +A+ + TP VA G+
Sbjct: 386 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 445
Query: 288 LDLAEVIKNY 297
+++ + ++
Sbjct: 446 VNIVSQLMHH 455
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/189 (26%), Positives = 85/189 (44%), Gaps = 2/189 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
++G TPL IAA + + L+N A +D+ R+ T +H A ++ + VK LL+ G
Sbjct: 233 KSGFTPLHIAAHYGN-INVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A + K GLTPL+ + + ++ E LL A I + G +H A + + V
Sbjct: 292 AKIDAKTRDGLTPLHCGARSGHEQVV-EMLLDRAAPILSKTKNGLSPLHMATQGDHLNCV 350
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL + ++ T LHV A A+ LL + + A TP +A
Sbjct: 351 QLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKK 410
Query: 286 GNLDLAEVI 294
+ + E++
Sbjct: 411 NRIKVMELL 419
Score = 61.7 bits (143), Expect = 6e-09
Identities = 54/219 (24%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
+L G ++K G+D N C + G L +A+ + +++ L+ A +D
Sbjct: 45 YLRAARAGHLEKALDYIKNGVDINI-CNQNGLNALHLASK-EGHVEVVSELLQREANVDA 102
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
T+ G+TA+H A E VK L+ GA+ N + G TPLY++ + + + LL
Sbjct: 103 ATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMA-AQENHLEVVKFLLD 161
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+ A+ G+ + A + G Q V LL + + + LH+ A
Sbjct: 162 NGASQSLATEDGFTPLAVALQQGHDQVVSLLL----ENDTKGKVRLPALHIAARKDDTKA 217
Query: 258 ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
A LL + + + + TP +A GN+++A ++ N
Sbjct: 218 AALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLN 256
Score = 57.6 bits (133), Expect = 1e-07
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 1/190 (0%)
Query: 111 PLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY 170
P A K K L+ D ++ G T +H A ++ LL A+ ++
Sbjct: 204 PALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF 263
Query: 171 KDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLF 230
+TPL+++ + + + + + LL A I A G +H R+G Q V+ LL
Sbjct: 264 TARNDITPLHVA-SKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Query: 231 YGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDL 290
A + ++ +G +PLH+ +C + LL + + T VA G+ +
Sbjct: 323 RAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKV 382
Query: 291 AEVIKNYKSD 300
A+V+ + K++
Sbjct: 383 AKVLLDKKAN 392
Score = 54.4 bits (125), Expect = 9e-07
Identities = 52/210 (24%), Positives = 84/210 (40%), Gaps = 7/210 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
GQ + + G + N Q G TPL +AA ++ +++ L++ GA T DG T
Sbjct: 118 GQAEVVKVLVTNGANVNAQSQN-GFTPLYMAAQ-ENHLEVVKFLLDNGASQSLATEDGFT 175
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+ A+++ + V LLE N GK P K D LL +
Sbjct: 176 PLAVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADV 230
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
G+ +H A G + LL A ++ + TPLHV + + + LL R
Sbjct: 231 ESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDR 290
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
G +A TP +G+ + E++
Sbjct: 291 GAKIDAKTRDGLTPLHCGARSGHEQVVEML 320
>AL592430-3|CAI40518.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 93.5 bits (222), Expect = 2e-18
Identities = 64/216 (29%), Positives = 101/216 (46%), Gaps = 3/216 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ +++ G PN GET L +AA A+++ LV GA ++ + +D T
Sbjct: 444 GHVNIVSQLMHHGASPNT-TNVRGETALHMAAR-SGQAEVVRYLVQDGAQVEAKAKDDQT 501
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+H + + V+ LL+ GASPN G TPL+LS + + L H A++
Sbjct: 502 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG-ASLSI 560
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T +G+ +H A + G ++ + LL A +A SG TPLHV A A LL +
Sbjct: 561 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 620
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G A TP +A +D+A + Y +D
Sbjct: 621 GASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGAD 656
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/214 (29%), Positives = 94/214 (43%), Gaps = 5/214 (2%)
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
H H ++ K+ K +PN G TPL IA K+ K++ L+ GA + T
Sbjct: 376 HCGHYKVAKVL--LDKKANPNAKALN-GFTPLHIACK-KNRIKVMELLLKHGASIQAVTE 431
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
G T +H A + V L+ GASPN + +G T L+++ + ++ L+ D A
Sbjct: 432 SGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVV-RYLVQDGA 490
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ A +H + R G V LL GA NA SG TPLH+ A + A
Sbjct: 491 QVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 550
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL G TP VA G L++A ++
Sbjct: 551 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 79.4 bits (187), Expect = 3e-14
Identities = 52/158 (32%), Positives = 73/158 (46%), Gaps = 1/158 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D T D TA+H A + K LL+ A+PN K G TPL+++ K + E
Sbjct: 360 VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIAC-KKNRIKVMEL 418
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL A+I A G +H A G V V L+ +GA N N G T LH+ A + Q
Sbjct: 419 LLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQ 478
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAE 292
R L+ G EA +QTP ++ G D+ +
Sbjct: 479 AEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQ 516
Score = 76.6 bits (180), Expect = 2e-13
Identities = 47/175 (26%), Positives = 91/175 (52%), Gaps = 1/175 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
K+ L++ A + + +G T +H A +KN ++ ++ LL+ GAS GLTP++++
Sbjct: 381 KVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVA 440
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
++ + L+H A+ T+++G +H A R+G + V +L+ GA + A+
Sbjct: 441 AFMGHVNIVSQ-LMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 499
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
TPLH+ A + +QLL +G A + TP ++ G+ D+A + ++
Sbjct: 500 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDH 554
Score = 73.3 bits (172), Expect = 2e-12
Identities = 55/190 (28%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G TPL IAA K+ I L+ GA + TR G ++H A ++ ++ V LL G
Sbjct: 629 KNGYTPLHIAAK-KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL--G 685
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ N GLTPL+L+ + + E L++ A + A G+ +H C G ++ V
Sbjct: 686 RNANVS---GLTPLHLAA-QEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIV 741
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+ LL + A +NA+ +G TPLH A LL L T +A
Sbjct: 742 NFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRL 801
Query: 286 GNLDLAEVIK 295
G + + + +K
Sbjct: 802 GYISVVDTLK 811
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/187 (29%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IA+ L A+++ LV GA ++ ++++G T ++ A ++N LE VK LL+ GAS
Sbjct: 107 GNTALHIAS-LAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGAS 165
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ G TPL +++ D ++ +LL ++ T G L +H A R +
Sbjct: 166 QSLATEDGFTPLAVALQQGHDQVV--SLLLENDTKGKVRLPA---LHIAARKDDTKAAAL 220
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL + + + SG TPLH+ A + A LL R + + TP VA GN
Sbjct: 221 LLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGN 280
Query: 288 LDLAEVI 294
++ +++
Sbjct: 281 ANMVKLL 287
Score = 70.5 bits (165), Expect = 1e-11
Identities = 57/192 (29%), Positives = 84/192 (43%), Gaps = 7/192 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A D + G T +H A ++ + LL+ GAS
Sbjct: 565 GFTPLHVAAKY-GKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGAS 623
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ K + TLL A A QG VH A + G V V
Sbjct: 624 PHAAAKNGYTPLHIAA-KKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSL 682
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A N SG TPLH+ A + + A L+ +G +A TP V GN
Sbjct: 683 LLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN 737
Query: 288 LDLAEVIKNYKS 299
+ + + + +
Sbjct: 738 IKIVNFLLQHSA 749
Score = 70.1 bits (164), Expect = 2e-11
Identities = 53/190 (27%), Positives = 89/190 (46%), Gaps = 6/190 (3%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL +A+ + A ++ L++ GA +D +TRDG T +H + V+ LL+ A
Sbjct: 270 TPLHVASK-RGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPIL 328
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQG--WQEVHQACRNGLVQHVDH 227
K GL+PL+++ D L C LL H + D+ +H A G +
Sbjct: 329 SKTKNGLSPLHMATQG--DHLNCVQLLLQH-NVPVDDVTNDYLTALHVAAHCGHYKVAKV 385
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A+ NA+ +G TPLH+ + LL G +A+ + TP VA G+
Sbjct: 386 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 445
Query: 288 LDLAEVIKNY 297
+++ + ++
Sbjct: 446 VNIVSQLMHH 455
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/189 (26%), Positives = 85/189 (44%), Gaps = 2/189 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
++G TPL IAA + + L+N A +D+ R+ T +H A ++ + VK LL+ G
Sbjct: 233 KSGFTPLHIAAHYGN-INVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A + K GLTPL+ + + ++ E LL A I + G +H A + + V
Sbjct: 292 AKIDAKTRDGLTPLHCGARSGHEQVV-EMLLDRAAPILSKTKNGLSPLHMATQGDHLNCV 350
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL + ++ T LHV A A+ LL + + A TP +A
Sbjct: 351 QLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKK 410
Query: 286 GNLDLAEVI 294
+ + E++
Sbjct: 411 NRIKVMELL 419
Score = 62.1 bits (144), Expect = 5e-09
Identities = 53/211 (25%), Positives = 91/211 (43%), Gaps = 8/211 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
+G+++ K P+ ++G TPL +AA + K+ + L++ GA ++G
Sbjct: 575 YGKLEVANLLLQKSASPDA-AGKSGLTPLHVAAHYDNQ-KVALLLLDQGASPHAAAKNGY 632
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A +KN ++ TLLE GA N +G+ ++L+ ++ LL +A +
Sbjct: 633 TPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMV-SLLLGRNANV- 690
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
G +H A + V + L+ GA ++A+ G TPLHV LL
Sbjct: 691 ----SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 746
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
A TP A G+ + V+
Sbjct: 747 HSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 777
Score = 61.7 bits (143), Expect = 6e-09
Identities = 54/219 (24%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
+L G ++K G+D N C + G L +A+ + +++ L+ A +D
Sbjct: 45 YLRAARAGHLEKALDYIKNGVDINI-CNQNGLNALHLASK-EGHVEVVSELLQREANVDA 102
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
T+ G+TA+H A E VK L+ GA+ N + G TPLY++ + + + LL
Sbjct: 103 ATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMA-AQENHLEVVKFLLD 161
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+ A+ G+ + A + G Q V LL + + + LH+ A
Sbjct: 162 NGASQSLATEDGFTPLAVALQQGHDQVVSLLL----ENDTKGKVRLPALHIAARKDDTKA 217
Query: 258 ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
A LL + + + + TP +A GN+++A ++ N
Sbjct: 218 AALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLN 256
Score = 57.6 bits (133), Expect = 1e-07
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 1/190 (0%)
Query: 111 PLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY 170
P A K K L+ D ++ G T +H A ++ LL A+ ++
Sbjct: 204 PALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF 263
Query: 171 KDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLF 230
+TPL+++ + + + + + LL A I A G +H R+G Q V+ LL
Sbjct: 264 TARNDITPLHVA-SKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Query: 231 YGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDL 290
A + ++ +G +PLH+ +C + LL + + T VA G+ +
Sbjct: 323 RAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKV 382
Query: 291 AEVIKNYKSD 300
A+V+ + K++
Sbjct: 383 AKVLLDKKAN 392
Score = 54.4 bits (125), Expect = 9e-07
Identities = 52/210 (24%), Positives = 84/210 (40%), Gaps = 7/210 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
GQ + + G + N Q G TPL +AA ++ +++ L++ GA T DG T
Sbjct: 118 GQAEVVKVLVTNGANVNAQSQN-GFTPLYMAAQ-ENHLEVVKFLLDNGASQSLATEDGFT 175
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+ A+++ + V LLE N GK P K D LL +
Sbjct: 176 PLAVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADV 230
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
G+ +H A G + LL A ++ + TPLHV + + + LL R
Sbjct: 231 ESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDR 290
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
G +A TP +G+ + E++
Sbjct: 291 GAKIDAKTRDGLTPLHCGARSGHEQVVEML 320
>AL592430-2|CAI40517.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 93.5 bits (222), Expect = 2e-18
Identities = 64/216 (29%), Positives = 101/216 (46%), Gaps = 3/216 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ +++ G PN GET L +AA A+++ LV GA ++ + +D T
Sbjct: 59 GHVNIVSQLMHHGASPNT-TNVRGETALHMAAR-SGQAEVVRYLVQDGAQVEAKAKDDQT 116
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+H + + V+ LL+ GASPN G TPL+LS + + L H A++
Sbjct: 117 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG-ASLSI 175
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T +G+ +H A + G ++ + LL A +A SG TPLHV A A LL +
Sbjct: 176 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 235
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G A TP +A +D+A + Y +D
Sbjct: 236 GASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGAD 271
Score = 79.0 bits (186), Expect = 4e-14
Identities = 58/187 (31%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL IA K+ K++ L+ GA + T G T +H A + V L+ GAS
Sbjct: 15 GFTPLHIACK-KNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 73
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
PN + +G T L+++ + ++ L+ D A + A +H + R G V
Sbjct: 74 PNTTNVRGETALHMAARSGQAEVV-RYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 132
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL GA NA SG TPLH+ A + A LL G TP VA G
Sbjct: 133 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 192
Query: 288 LDLAEVI 294
L++A ++
Sbjct: 193 LEVANLL 199
Score = 75.4 bits (177), Expect = 5e-13
Identities = 44/157 (28%), Positives = 83/157 (52%), Gaps = 1/157 (0%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
+G T +H A +KN ++ ++ LL+ GAS GLTP++++ ++ + L+H A
Sbjct: 14 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQ-LMHHGA 72
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ T+++G +H A R+G + V +L+ GA + A+ TPLH+ A + +Q
Sbjct: 73 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 132
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
LL +G A + TP ++ G+ D+A + ++
Sbjct: 133 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDH 169
Score = 73.3 bits (172), Expect = 2e-12
Identities = 55/190 (28%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G TPL IAA K+ I L+ GA + TR G ++H A ++ ++ V LL G
Sbjct: 244 KNGYTPLHIAAK-KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL--G 300
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ N GLTPL+L+ + + E L++ A + A G+ +H C G ++ V
Sbjct: 301 RNANVS---GLTPLHLAA-QEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIV 356
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+ LL + A +NA+ +G TPLH A LL L T +A
Sbjct: 357 NFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRL 416
Query: 286 GNLDLAEVIK 295
G + + + +K
Sbjct: 417 GYISVVDTLK 426
Score = 70.5 bits (165), Expect = 1e-11
Identities = 57/192 (29%), Positives = 84/192 (43%), Gaps = 7/192 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A D + G T +H A ++ + LL+ GAS
Sbjct: 180 GFTPLHVAAKY-GKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGAS 238
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ K + TLL A A QG VH A + G V V
Sbjct: 239 PHAAAKNGYTPLHIAA-KKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSL 297
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A N SG TPLH+ A + + A L+ +G +A TP V GN
Sbjct: 298 LLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN 352
Query: 288 LDLAEVIKNYKS 299
+ + + + +
Sbjct: 353 IKIVNFLLQHSA 364
Score = 68.1 bits (159), Expect = 7e-11
Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Query: 161 LLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG 220
LL+ A+PN K G TPL+++ K + E LL A+I A G +H A G
Sbjct: 1 LLDKKANPNAKALNGFTPLHIAC-KKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMG 59
Query: 221 LVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQ 280
V V L+ +GA N N G T LH+ A + Q R L+ G EA +QTP
Sbjct: 60 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 119
Query: 281 VAVIAGNLDLAE 292
++ G D+ +
Sbjct: 120 ISARLGKADIVQ 131
Score = 62.1 bits (144), Expect = 5e-09
Identities = 53/211 (25%), Positives = 91/211 (43%), Gaps = 8/211 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
+G+++ K P+ ++G TPL +AA + K+ + L++ GA ++G
Sbjct: 190 YGKLEVANLLLQKSASPDA-AGKSGLTPLHVAAHYDNQ-KVALLLLDQGASPHAAAKNGY 247
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A +KN ++ TLLE GA N +G+ ++L+ ++ LL +A +
Sbjct: 248 TPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMV-SLLLGRNANV- 305
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
G +H A + V + L+ GA ++A+ G TPLHV LL
Sbjct: 306 ----SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 361
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
A TP A G+ + V+
Sbjct: 362 HSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 392
Score = 52.4 bits (120), Expect = 4e-06
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 3/106 (2%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL A A L G+ +H AC+ ++ ++ LL +GA + A SG TP+HV A
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ QL+ G N +T +A +G AEV++ D
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQ---AEVVRYLVQD 103
>AL359377-2|CAI41373.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 93.5 bits (222), Expect = 2e-18
Identities = 64/216 (29%), Positives = 101/216 (46%), Gaps = 3/216 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ +++ G PN GET L +AA A+++ LV GA ++ + +D T
Sbjct: 444 GHVNIVSQLMHHGASPNT-TNVRGETALHMAAR-SGQAEVVRYLVQDGAQVEAKAKDDQT 501
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+H + + V+ LL+ GASPN G TPL+LS + + L H A++
Sbjct: 502 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG-ASLSI 560
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T +G+ +H A + G ++ + LL A +A SG TPLHV A A LL +
Sbjct: 561 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 620
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G A TP +A +D+A + Y +D
Sbjct: 621 GASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGAD 656
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/214 (29%), Positives = 94/214 (43%), Gaps = 5/214 (2%)
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
H H ++ K+ K +PN G TPL IA K+ K++ L+ GA + T
Sbjct: 376 HCGHYKVAKVL--LDKKANPNAKALN-GFTPLHIACK-KNRIKVMELLLKHGASIQAVTE 431
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
G T +H A + V L+ GASPN + +G T L+++ + ++ L+ D A
Sbjct: 432 SGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVV-RYLVQDGA 490
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ A +H + R G V LL GA NA SG TPLH+ A + A
Sbjct: 491 QVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 550
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL G TP VA G L++A ++
Sbjct: 551 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 79.4 bits (187), Expect = 3e-14
Identities = 52/158 (32%), Positives = 73/158 (46%), Gaps = 1/158 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D T D TA+H A + K LL+ A+PN K G TPL+++ K + E
Sbjct: 360 VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIAC-KKNRIKVMEL 418
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL A+I A G +H A G V V L+ +GA N N G T LH+ A + Q
Sbjct: 419 LLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQ 478
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAE 292
R L+ G EA +QTP ++ G D+ +
Sbjct: 479 AEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQ 516
Score = 76.6 bits (180), Expect = 2e-13
Identities = 47/175 (26%), Positives = 91/175 (52%), Gaps = 1/175 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
K+ L++ A + + +G T +H A +KN ++ ++ LL+ GAS GLTP++++
Sbjct: 381 KVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVA 440
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
++ + L+H A+ T+++G +H A R+G + V +L+ GA + A+
Sbjct: 441 AFMGHVNIVSQ-LMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 499
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
TPLH+ A + +QLL +G A + TP ++ G+ D+A + ++
Sbjct: 500 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDH 554
Score = 73.3 bits (172), Expect = 2e-12
Identities = 55/190 (28%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G TPL IAA K+ I L+ GA + TR G ++H A ++ ++ V LL G
Sbjct: 629 KNGYTPLHIAAK-KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL--G 685
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ N GLTPL+L+ + + E L++ A + A G+ +H C G ++ V
Sbjct: 686 RNANVS---GLTPLHLAA-QEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIV 741
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+ LL + A +NA+ +G TPLH A LL L T +A
Sbjct: 742 NFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRL 801
Query: 286 GNLDLAEVIK 295
G + + + +K
Sbjct: 802 GYISVVDTLK 811
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/187 (29%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IA+ L A+++ LV GA ++ ++++G T ++ A ++N LE VK LL+ GAS
Sbjct: 107 GNTALHIAS-LAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGAS 165
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ G TPL +++ D ++ +LL ++ T G L +H A R +
Sbjct: 166 QSLATEDGFTPLAVALQQGHDQVV--SLLLENDTKGKVRLPA---LHIAARKDDTKAAAL 220
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL + + + SG TPLH+ A + A LL R + + TP VA GN
Sbjct: 221 LLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGN 280
Query: 288 LDLAEVI 294
++ +++
Sbjct: 281 ANMVKLL 287
Score = 70.5 bits (165), Expect = 1e-11
Identities = 57/192 (29%), Positives = 84/192 (43%), Gaps = 7/192 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A D + G T +H A ++ + LL+ GAS
Sbjct: 565 GFTPLHVAAKY-GKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGAS 623
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ K + TLL A A QG VH A + G V V
Sbjct: 624 PHAAAKNGYTPLHIAA-KKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSL 682
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A N SG TPLH+ A + + A L+ +G +A TP V GN
Sbjct: 683 LLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN 737
Query: 288 LDLAEVIKNYKS 299
+ + + + +
Sbjct: 738 IKIVNFLLQHSA 749
Score = 70.1 bits (164), Expect = 2e-11
Identities = 53/190 (27%), Positives = 89/190 (46%), Gaps = 6/190 (3%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL +A+ + A ++ L++ GA +D +TRDG T +H + V+ LL+ A
Sbjct: 270 TPLHVASK-RGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPIL 328
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQG--WQEVHQACRNGLVQHVDH 227
K GL+PL+++ D L C LL H + D+ +H A G +
Sbjct: 329 SKTKNGLSPLHMATQG--DHLNCVQLLLQH-NVPVDDVTNDYLTALHVAAHCGHYKVAKV 385
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A+ NA+ +G TPLH+ + LL G +A+ + TP VA G+
Sbjct: 386 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 445
Query: 288 LDLAEVIKNY 297
+++ + ++
Sbjct: 446 VNIVSQLMHH 455
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/189 (26%), Positives = 85/189 (44%), Gaps = 2/189 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
++G TPL IAA + + L+N A +D+ R+ T +H A ++ + VK LL+ G
Sbjct: 233 KSGFTPLHIAAHYGN-INVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A + K GLTPL+ + + ++ E LL A I + G +H A + + V
Sbjct: 292 AKIDAKTRDGLTPLHCGARSGHEQVV-EMLLDRAAPILSKTKNGLSPLHMATQGDHLNCV 350
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL + ++ T LHV A A+ LL + + A TP +A
Sbjct: 351 QLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKK 410
Query: 286 GNLDLAEVI 294
+ + E++
Sbjct: 411 NRIKVMELL 419
Score = 62.1 bits (144), Expect = 5e-09
Identities = 53/211 (25%), Positives = 91/211 (43%), Gaps = 8/211 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
+G+++ K P+ ++G TPL +AA + K+ + L++ GA ++G
Sbjct: 575 YGKLEVANLLLQKSASPDA-AGKSGLTPLHVAAHYDNQ-KVALLLLDQGASPHAAAKNGY 632
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A +KN ++ TLLE GA N +G+ ++L+ ++ LL +A +
Sbjct: 633 TPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMV-SLLLGRNANV- 690
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
G +H A + V + L+ GA ++A+ G TPLHV LL
Sbjct: 691 ----SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 746
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
A TP A G+ + V+
Sbjct: 747 HSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 777
Score = 61.7 bits (143), Expect = 6e-09
Identities = 54/219 (24%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
+L G ++K G+D N C + G L +A+ + +++ L+ A +D
Sbjct: 45 YLRAARAGHLEKALDYIKNGVDINI-CNQNGLNALHLASK-EGHVEVVSELLQREANVDA 102
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
T+ G+TA+H A E VK L+ GA+ N + G TPLY++ + + + LL
Sbjct: 103 ATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMA-AQENHLEVVKFLLD 161
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+ A+ G+ + A + G Q V LL + + + LH+ A
Sbjct: 162 NGASQSLATEDGFTPLAVALQQGHDQVVSLLL----ENDTKGKVRLPALHIAARKDDTKA 217
Query: 258 ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
A LL + + + + TP +A GN+++A ++ N
Sbjct: 218 AALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLN 256
Score = 57.6 bits (133), Expect = 1e-07
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 1/190 (0%)
Query: 111 PLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY 170
P A K K L+ D ++ G T +H A ++ LL A+ ++
Sbjct: 204 PALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF 263
Query: 171 KDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLF 230
+TPL+++ + + + + + LL A I A G +H R+G Q V+ LL
Sbjct: 264 TARNDITPLHVA-SKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Query: 231 YGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDL 290
A + ++ +G +PLH+ +C + LL + + T VA G+ +
Sbjct: 323 RAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKV 382
Query: 291 AEVIKNYKSD 300
A+V+ + K++
Sbjct: 383 AKVLLDKKAN 392
Score = 54.4 bits (125), Expect = 9e-07
Identities = 52/210 (24%), Positives = 84/210 (40%), Gaps = 7/210 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
GQ + + G + N Q G TPL +AA ++ +++ L++ GA T DG T
Sbjct: 118 GQAEVVKVLVTNGANVNAQSQN-GFTPLYMAAQ-ENHLEVVKFLLDNGASQSLATEDGFT 175
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+ A+++ + V LLE N GK P K D LL +
Sbjct: 176 PLAVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADV 230
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
G+ +H A G + LL A ++ + TPLHV + + + LL R
Sbjct: 231 ESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDR 290
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
G +A TP +G+ + E++
Sbjct: 291 GAKIDAKTRDGLTPLHCGARSGHEQVVEML 320
>AL359377-1|CAI41372.1| 1071|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 1071
Score = 93.5 bits (222), Expect = 2e-18
Identities = 64/216 (29%), Positives = 101/216 (46%), Gaps = 3/216 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ +++ G PN GET L +AA A+++ LV GA ++ + +D T
Sbjct: 59 GHVNIVSQLMHHGASPNT-TNVRGETALHMAAR-SGQAEVVRYLVQDGAQVEAKAKDDQT 116
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+H + + V+ LL+ GASPN G TPL+LS + + L H A++
Sbjct: 117 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG-ASLSI 175
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T +G+ +H A + G ++ + LL A +A SG TPLHV A A LL +
Sbjct: 176 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 235
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G A TP +A +D+A + Y +D
Sbjct: 236 GASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGAD 271
Score = 79.0 bits (186), Expect = 4e-14
Identities = 58/187 (31%), Positives = 84/187 (44%), Gaps = 2/187 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL IA K+ K++ L+ GA + T G T +H A + V L+ GAS
Sbjct: 15 GFTPLHIACK-KNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGAS 73
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
PN + +G T L+++ + ++ L+ D A + A +H + R G V
Sbjct: 74 PNTTNVRGETALHMAARSGQAEVV-RYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 132
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL GA NA SG TPLH+ A + A LL G TP VA G
Sbjct: 133 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHGASLSITTKKGFTPLHVAAKYGK 192
Query: 288 LDLAEVI 294
L++A ++
Sbjct: 193 LEVANLL 199
Score = 75.4 bits (177), Expect = 5e-13
Identities = 44/157 (28%), Positives = 83/157 (52%), Gaps = 1/157 (0%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
+G T +H A +KN ++ ++ LL+ GAS GLTP++++ ++ + L+H A
Sbjct: 14 NGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQ-LMHHGA 72
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ T+++G +H A R+G + V +L+ GA + A+ TPLH+ A + +Q
Sbjct: 73 SPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 132
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
LL +G A + TP ++ G+ D+A + ++
Sbjct: 133 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDH 169
Score = 73.3 bits (172), Expect = 2e-12
Identities = 55/190 (28%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G TPL IAA K+ I L+ GA + TR G ++H A ++ ++ V LL G
Sbjct: 244 KNGYTPLHIAAK-KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL--G 300
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ N GLTPL+L+ + + E L++ A + A G+ +H C G ++ V
Sbjct: 301 RNANVS---GLTPLHLAA-QEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIV 356
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+ LL + A +NA+ +G TPLH A LL L T +A
Sbjct: 357 NFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRL 416
Query: 286 GNLDLAEVIK 295
G + + + +K
Sbjct: 417 GYISVVDTLK 426
Score = 70.5 bits (165), Expect = 1e-11
Identities = 57/192 (29%), Positives = 84/192 (43%), Gaps = 7/192 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A D + G T +H A ++ + LL+ GAS
Sbjct: 180 GFTPLHVAAKY-GKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGAS 238
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ K + TLL A A QG VH A + G V V
Sbjct: 239 PHAAAKNGYTPLHIAA-KKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSL 297
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A N SG TPLH+ A + + A L+ +G +A TP V GN
Sbjct: 298 LLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN 352
Query: 288 LDLAEVIKNYKS 299
+ + + + +
Sbjct: 353 IKIVNFLLQHSA 364
Score = 68.1 bits (159), Expect = 7e-11
Identities = 44/132 (33%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Query: 161 LLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG 220
LL+ A+PN K G TPL+++ K + E LL A+I A G +H A G
Sbjct: 1 LLDKKANPNAKALNGFTPLHIAC-KKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMG 59
Query: 221 LVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQ 280
V V L+ +GA N N G T LH+ A + Q R L+ G EA +QTP
Sbjct: 60 HVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLH 119
Query: 281 VAVIAGNLDLAE 292
++ G D+ +
Sbjct: 120 ISARLGKADIVQ 131
Score = 62.1 bits (144), Expect = 5e-09
Identities = 53/211 (25%), Positives = 91/211 (43%), Gaps = 8/211 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
+G+++ K P+ ++G TPL +AA + K+ + L++ GA ++G
Sbjct: 190 YGKLEVANLLLQKSASPDA-AGKSGLTPLHVAAHYDNQ-KVALLLLDQGASPHAAAKNGY 247
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A +KN ++ TLLE GA N +G+ ++L+ ++ LL +A +
Sbjct: 248 TPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMV-SLLLGRNANV- 305
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
G +H A + V + L+ GA ++A+ G TPLHV LL
Sbjct: 306 ----SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 361
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
A TP A G+ + V+
Sbjct: 362 HSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 392
Score = 52.4 bits (120), Expect = 4e-06
Identities = 32/106 (30%), Positives = 49/106 (46%), Gaps = 3/106 (2%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL A A L G+ +H AC+ ++ ++ LL +GA + A SG TP+HV A
Sbjct: 1 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 60
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ QL+ G N +T +A +G AEV++ D
Sbjct: 61 VNIVSQLMHHGASPNTTNVRGETALHMAARSGQ---AEVVRYLVQD 103
>AL359267-1|CAH73232.1| 4372|Homo sapiens ankyrin 3, node of Ranvier
(ankyrin G) protein.
Length = 4372
Score = 93.5 bits (222), Expect = 2e-18
Identities = 64/216 (29%), Positives = 101/216 (46%), Gaps = 3/216 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ +++ G PN GET L +AA A+++ LV GA ++ + +D T
Sbjct: 444 GHVNIVSQLMHHGASPNT-TNVRGETALHMAAR-SGQAEVVRYLVQDGAQVEAKAKDDQT 501
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+H + + V+ LL+ GASPN G TPL+LS + + L H A++
Sbjct: 502 PLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG-ASLSI 560
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T +G+ +H A + G ++ + LL A +A SG TPLHV A A LL +
Sbjct: 561 TTKKGFTPLHVAAKYGKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQ 620
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G A TP +A +D+A + Y +D
Sbjct: 621 GASPHAAAKNGYTPLHIAAKKNQMDIATTLLEYGAD 656
Score = 80.2 bits (189), Expect = 2e-14
Identities = 64/214 (29%), Positives = 94/214 (43%), Gaps = 5/214 (2%)
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
H H ++ K+ K +PN G TPL IA K+ K++ L+ GA + T
Sbjct: 376 HCGHYKVAKVL--LDKKANPNAKALN-GFTPLHIACK-KNRIKVMELLLKHGASIQAVTE 431
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
G T +H A + V L+ GASPN + +G T L+++ + ++ L+ D A
Sbjct: 432 SGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQAEVV-RYLVQDGA 490
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ A +H + R G V LL GA NA SG TPLH+ A + A
Sbjct: 491 QVEAKAKDDQTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAF 550
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL G TP VA G L++A ++
Sbjct: 551 LLDHGASLSITTKKGFTPLHVAAKYGKLEVANLL 584
Score = 79.4 bits (187), Expect = 3e-14
Identities = 52/158 (32%), Positives = 73/158 (46%), Gaps = 1/158 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D T D TA+H A + K LL+ A+PN K G TPL+++ K + E
Sbjct: 360 VDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIAC-KKNRIKVMEL 418
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL A+I A G +H A G V V L+ +GA N N G T LH+ A + Q
Sbjct: 419 LLKHGASIQAVTESGLTPIHVAAFMGHVNIVSQLMHHGASPNTTNVRGETALHMAARSGQ 478
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAE 292
R L+ G EA +QTP ++ G D+ +
Sbjct: 479 AEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQ 516
Score = 76.6 bits (180), Expect = 2e-13
Identities = 47/175 (26%), Positives = 91/175 (52%), Gaps = 1/175 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
K+ L++ A + + +G T +H A +KN ++ ++ LL+ GAS GLTP++++
Sbjct: 381 KVAKVLLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVA 440
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
++ + L+H A+ T+++G +H A R+G + V +L+ GA + A+
Sbjct: 441 AFMGHVNIVSQ-LMHHGASPNTTNVRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDD 499
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
TPLH+ A + +QLL +G A + TP ++ G+ D+A + ++
Sbjct: 500 QTPLHISARLGKADIVQQLLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDH 554
Score = 73.3 bits (172), Expect = 2e-12
Identities = 55/190 (28%), Positives = 87/190 (45%), Gaps = 7/190 (3%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G TPL IAA K+ I L+ GA + TR G ++H A ++ ++ V LL G
Sbjct: 629 KNGYTPLHIAAK-KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLL--G 685
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ N GLTPL+L+ + + E L++ A + A G+ +H C G ++ V
Sbjct: 686 RNANVS---GLTPLHLAA-QEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIV 741
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+ LL + A +NA+ +G TPLH A LL L T +A
Sbjct: 742 NFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRL 801
Query: 286 GNLDLAEVIK 295
G + + + +K
Sbjct: 802 GYISVVDTLK 811
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/187 (29%), Positives = 94/187 (50%), Gaps = 6/187 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IA+ L A+++ LV GA ++ ++++G T ++ A ++N LE VK LL+ GAS
Sbjct: 107 GNTALHIAS-LAGQAEVVKVLVTNGANVNAQSQNGFTPLYMAAQENHLEVVKFLLDNGAS 165
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ G TPL +++ D ++ +LL ++ T G L +H A R +
Sbjct: 166 QSLATEDGFTPLAVALQQGHDQVV--SLLLENDTKGKVRLPA---LHIAARKDDTKAAAL 220
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL + + + SG TPLH+ A + A LL R + + TP VA GN
Sbjct: 221 LLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGN 280
Query: 288 LDLAEVI 294
++ +++
Sbjct: 281 ANMVKLL 287
Score = 70.5 bits (165), Expect = 1e-11
Identities = 57/192 (29%), Positives = 84/192 (43%), Gaps = 7/192 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A D + G T +H A ++ + LL+ GAS
Sbjct: 565 GFTPLHVAAKY-GKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGAS 623
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ K + TLL A A QG VH A + G V V
Sbjct: 624 PHAAAKNGYTPLHIAA-KKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSL 682
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A N SG TPLH+ A + + A L+ +G +A TP V GN
Sbjct: 683 LLGRNA-----NVSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN 737
Query: 288 LDLAEVIKNYKS 299
+ + + + +
Sbjct: 738 IKIVNFLLQHSA 749
Score = 70.1 bits (164), Expect = 2e-11
Identities = 53/190 (27%), Positives = 89/190 (46%), Gaps = 6/190 (3%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL +A+ + A ++ L++ GA +D +TRDG T +H + V+ LL+ A
Sbjct: 270 TPLHVASK-RGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLDRAAPIL 328
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQG--WQEVHQACRNGLVQHVDH 227
K GL+PL+++ D L C LL H + D+ +H A G +
Sbjct: 329 SKTKNGLSPLHMATQG--DHLNCVQLLLQH-NVPVDDVTNDYLTALHVAAHCGHYKVAKV 385
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A+ NA+ +G TPLH+ + LL G +A+ + TP VA G+
Sbjct: 386 LLDKKANPNAKALNGFTPLHIACKKNRIKVMELLLKHGASIQAVTESGLTPIHVAAFMGH 445
Query: 288 LDLAEVIKNY 297
+++ + ++
Sbjct: 446 VNIVSQLMHH 455
Score = 62.5 bits (145), Expect = 4e-09
Identities = 51/189 (26%), Positives = 85/189 (44%), Gaps = 2/189 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
++G TPL IAA + + L+N A +D+ R+ T +H A ++ + VK LL+ G
Sbjct: 233 KSGFTPLHIAAHYGN-INVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDRG 291
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A + K GLTPL+ + + ++ E LL A I + G +H A + + V
Sbjct: 292 AKIDAKTRDGLTPLHCGARSGHEQVV-EMLLDRAAPILSKTKNGLSPLHMATQGDHLNCV 350
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL + ++ T LHV A A+ LL + + A TP +A
Sbjct: 351 QLLLQHNVPVDDVTNDYLTALHVAAHCGHYKVAKVLLDKKANPNAKALNGFTPLHIACKK 410
Query: 286 GNLDLAEVI 294
+ + E++
Sbjct: 411 NRIKVMELL 419
Score = 62.1 bits (144), Expect = 5e-09
Identities = 53/211 (25%), Positives = 91/211 (43%), Gaps = 8/211 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
+G+++ K P+ ++G TPL +AA + K+ + L++ GA ++G
Sbjct: 575 YGKLEVANLLLQKSASPDA-AGKSGLTPLHVAAHYDNQ-KVALLLLDQGASPHAAAKNGY 632
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A +KN ++ TLLE GA N +G+ ++L+ ++ LL +A +
Sbjct: 633 TPLHIAAKKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMV-SLLLGRNANV- 690
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
G +H A + V + L+ GA ++A+ G TPLHV LL
Sbjct: 691 ----SGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIVNFLLQ 746
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
A TP A G+ + V+
Sbjct: 747 HSAKVNAKTKNGYTPLHQAAQQGHTHIINVL 777
Score = 61.7 bits (143), Expect = 6e-09
Identities = 54/219 (24%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
+L G ++K G+D N C + G L +A+ + +++ L+ A +D
Sbjct: 45 YLRAARAGHLEKALDYIKNGVDINI-CNQNGLNALHLASK-EGHVEVVSELLQREANVDA 102
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
T+ G+TA+H A E VK L+ GA+ N + G TPLY++ + + + LL
Sbjct: 103 ATKKGNTALHIASLAGQAEVVKVLVTNGANVNAQSQNGFTPLYMA-AQENHLEVVKFLLD 161
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+ A+ G+ + A + G Q V LL + + + LH+ A
Sbjct: 162 NGASQSLATEDGFTPLAVALQQGHDQVVSLLL----ENDTKGKVRLPALHIAARKDDTKA 217
Query: 258 ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
A LL + + + + TP +A GN+++A ++ N
Sbjct: 218 AALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLN 256
Score = 57.6 bits (133), Expect = 1e-07
Identities = 44/190 (23%), Positives = 82/190 (43%), Gaps = 1/190 (0%)
Query: 111 PLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY 170
P A K K L+ D ++ G T +H A ++ LL A+ ++
Sbjct: 204 PALHIAARKDDTKAAALLLQNDNNADVESKSGFTPLHIAAHYGNINVATLLLNRAAAVDF 263
Query: 171 KDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLF 230
+TPL+++ + + + + + LL A I A G +H R+G Q V+ LL
Sbjct: 264 TARNDITPLHVA-SKRGNANMVKLLLDRGAKIDAKTRDGLTPLHCGARSGHEQVVEMLLD 322
Query: 231 YGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDL 290
A + ++ +G +PLH+ +C + LL + + T VA G+ +
Sbjct: 323 RAAPILSKTKNGLSPLHMATQGDHLNCVQLLLQHNVPVDDVTNDYLTALHVAAHCGHYKV 382
Query: 291 AEVIKNYKSD 300
A+V+ + K++
Sbjct: 383 AKVLLDKKAN 392
Score = 54.4 bits (125), Expect = 9e-07
Identities = 52/210 (24%), Positives = 84/210 (40%), Gaps = 7/210 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
GQ + + G + N Q G TPL +AA ++ +++ L++ GA T DG T
Sbjct: 118 GQAEVVKVLVTNGANVNAQSQN-GFTPLYMAAQ-ENHLEVVKFLLDNGASQSLATEDGFT 175
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+ A+++ + V LLE N GK P K D LL +
Sbjct: 176 PLAVALQQGHDQVVSLLLE-----NDTKGKVRLPALHIAARKDDTKAAALLLQNDNNADV 230
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
G+ +H A G + LL A ++ + TPLHV + + + LL R
Sbjct: 231 ESKSGFTPLHIAAHYGNINVATLLLNRAAAVDFTARNDITPLHVASKRGNANMVKLLLDR 290
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
G +A TP +G+ + E++
Sbjct: 291 GAKIDAKTRDGLTPLHCGARSGHEQVVEML 320
>AB209308-1|BAD92545.1| 931|Homo sapiens ankyrin 3 isoform 1
variant protein.
Length = 931
Score = 93.1 bits (221), Expect = 2e-18
Identities = 61/198 (30%), Positives = 94/198 (47%), Gaps = 2/198 (1%)
Query: 103 HCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL 162
H + GET L +AA A+++ LV GA ++ + +D T +H + + V+ LL
Sbjct: 5 HVPQRGETALHMAAR-SGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQLL 63
Query: 163 ELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLV 222
+ GASPN G TPL+LS + + L H A++ T +G+ +H A + G +
Sbjct: 64 QQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDHG-ASLSITTKKGFTPLHVAAKYGKL 122
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ + LL A +A SG TPLHV A A LL +G A TP +A
Sbjct: 123 EVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGASPHAAAKNGYTPLHIA 182
Query: 283 VIAGNLDLAEVIKNYKSD 300
+D+A + Y +D
Sbjct: 183 AKKNQMDIATTLLEYGAD 200
Score = 81.8 bits (193), Expect = 5e-15
Identities = 55/190 (28%), Positives = 88/190 (46%), Gaps = 2/190 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G TPL IAA K+ I L+ GA + TR G ++H A ++ ++ V LL
Sbjct: 173 KNGYTPLHIAAK-KNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSLLLGRN 231
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A+ N + GLTPL+L+ + + E L++ A + A G+ +H C G ++ V
Sbjct: 232 ANVNLSNKSGLTPLHLAA-QEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGNIKIV 290
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+ LL + A +NA+ +G TPLH A LL L T +A
Sbjct: 291 NFLLQHSAKVNAKTKNGYTPLHQAAQQGHTHIINVLLQNNASPNELTVNGNTALGIARRL 350
Query: 286 GNLDLAEVIK 295
G + + + +K
Sbjct: 351 GYISVVDTLK 360
Score = 80.2 bits (189), Expect = 2e-14
Identities = 58/192 (30%), Positives = 87/192 (45%), Gaps = 2/192 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A D + G T +H A ++ + LL+ GAS
Sbjct: 109 GFTPLHVAAKY-GKLEVANLLLQKSASPDAAGKSGLTPLHVAAHYDNQKVALLLLDQGAS 167
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ K + TLL A A QG VH A + G V V
Sbjct: 168 PHAAAKNGYTPLHIAA-KKNQMDIATTLLEYGADANAVTRQGIASVHLAAQEGHVDMVSL 226
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A++N N SG TPLH+ A + + A L+ +G +A TP V GN
Sbjct: 227 LLGRNANVNLSNKSGLTPLHLAAQEDRVNVAEVLVNQGAHVDAQTKMGYTPLHVGCHYGN 286
Query: 288 LDLAEVIKNYKS 299
+ + + + +
Sbjct: 287 IKIVNFLLQHSA 298
Score = 47.2 bits (107), Expect = 1e-04
Identities = 26/97 (26%), Positives = 47/97 (48%)
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
T+ +G +H A R+G + V +L+ GA + A+ TPLH+ A + +Q
Sbjct: 2 TLAHVPQRGETALHMAARSGQAEVVRYLVQDGAQVEAKAKDDQTPLHISARLGKADIVQQ 61
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
LL +G A + TP ++ G+ D+A + ++
Sbjct: 62 LLQQGASPNAATTSGYTPLHLSAREGHEDVAAFLLDH 98
>BC011608-1|AAH11608.2| 716|Homo sapiens EHMT1 protein protein.
Length = 716
Score = 89.8 bits (213), Expect = 2e-17
Identities = 68/243 (27%), Positives = 103/243 (42%), Gaps = 2/243 (0%)
Query: 58 MLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAG 117
++ LD + K L R + ++ G++ K+ G+DPNF + + AA
Sbjct: 142 LIALDSEKPKKL--RFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAA 199
Query: 118 LKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLT 177
I LV GA +D + D T + A E N LEAVK L++ GA + KD +G T
Sbjct: 200 EAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGST 259
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNA 237
L+L+ ++ L + + D GW + A V V LL G+D+N
Sbjct: 260 CLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINI 319
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
R+ N LH A + A LL CD A+N +P +A D + +
Sbjct: 320 RDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR 379
Query: 298 KSD 300
SD
Sbjct: 380 DSD 382
Score = 74.9 bits (176), Expect = 6e-13
Identities = 57/180 (31%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
C E TPL AA + + + L+ GAL+D + +GST +H A +K E V+ LL
Sbjct: 220 CSEDQRTPLMEAAE-NNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 278
Query: 164 LGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLV 222
G N +D G TP+ + K L+ + LL + I D + +H A +G V
Sbjct: 279 NGQMDVNCQDDGGWTPMIWATEYKHVDLV-KLLLSKGSDINIRDNEENICLHWAAFSGCV 337
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ LL D++A N G++PLH+ A + C L R D N +TP Q A
Sbjct: 338 DIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 397
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 1/154 (0%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA + L NG ++ + G T M A E ++ VK LL G+
Sbjct: 257 GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSD 316
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N +D + L+ + + + E LL + A ++ G +H A R V
Sbjct: 317 INIRDNEENICLHWAAFSGCVDI-AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVL 375
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
L +D+ +N G TPL ++N+Q A Q+
Sbjct: 376 FLSRDSDVTLKNKEGETPLQCASLNSQVWSALQM 409
>AY083210-1|AAM09024.1| 1267|Homo sapiens euchromatic histone
methyltransferase 1 protein.
Length = 1267
Score = 89.8 bits (213), Expect = 2e-17
Identities = 68/243 (27%), Positives = 103/243 (42%), Gaps = 2/243 (0%)
Query: 58 MLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAG 117
++ LD + K L R + ++ G++ K+ G+DPNF + + AA
Sbjct: 693 LIALDSEKPKKL--RFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAA 750
Query: 118 LKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLT 177
I LV GA +D + D T + A E N LEAVK L++ GA + KD +G T
Sbjct: 751 EAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGST 810
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNA 237
L+L+ ++ L + + D GW + A V V LL G+D+N
Sbjct: 811 CLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINI 870
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
R+ N LH A + A LL CD A+N +P +A D + +
Sbjct: 871 RDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR 930
Query: 298 KSD 300
SD
Sbjct: 931 DSD 933
Score = 74.9 bits (176), Expect = 6e-13
Identities = 57/180 (31%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
C E TPL AA + + + L+ GAL+D + +GST +H A +K E V+ LL
Sbjct: 771 CSEDQRTPLMEAAE-NNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 829
Query: 164 LGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLV 222
G N +D G TP+ + K L+ + LL + I D + +H A +G V
Sbjct: 830 NGQMDVNCQDDGGWTPMIWATEYKHVDLV-KLLLSKGSDINIRDNEENICLHWAAFSGCV 888
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ LL D++A N G++PLH+ A + C L R D N +TP Q A
Sbjct: 889 DIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 948
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 1/154 (0%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA + L NG ++ + G T M A E ++ VK LL G+
Sbjct: 808 GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSD 867
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N +D + L+ + + + E LL + A ++ G +H A R V
Sbjct: 868 INIRDNEENICLHWAAFSGCVDI-AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVL 926
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
L +D+ +N G TPL ++N+Q A Q+
Sbjct: 927 FLSRDSDVTLKNKEGETPLQCASLNSQVWSALQM 960
>AL611925-3|CAH71077.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 1 protein.
Length = 1267
Score = 89.8 bits (213), Expect = 2e-17
Identities = 68/243 (27%), Positives = 103/243 (42%), Gaps = 2/243 (0%)
Query: 58 MLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAG 117
++ LD + K L R + ++ G++ K+ G+DPNF + + AA
Sbjct: 693 LIALDSEKPKKL--RFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAA 750
Query: 118 LKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLT 177
I LV GA +D + D T + A E N LEAVK L++ GA + KD +G T
Sbjct: 751 EAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGST 810
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNA 237
L+L+ ++ L + + D GW + A V V LL G+D+N
Sbjct: 811 CLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINI 870
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
R+ N LH A + A LL CD A+N +P +A D + +
Sbjct: 871 RDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR 930
Query: 298 KSD 300
SD
Sbjct: 931 DSD 933
Score = 74.9 bits (176), Expect = 6e-13
Identities = 57/180 (31%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
C E TPL AA + + + L+ GAL+D + +GST +H A +K E V+ LL
Sbjct: 771 CSEDQRTPLMEAAE-NNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 829
Query: 164 LGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLV 222
G N +D G TP+ + K L+ + LL + I D + +H A +G V
Sbjct: 830 NGQMDVNCQDDGGWTPMIWATEYKHVDLV-KLLLSKGSDINIRDNEENICLHWAAFSGCV 888
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ LL D++A N G++PLH+ A + C L R D N +TP Q A
Sbjct: 889 DIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 948
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 1/154 (0%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA + L NG ++ + G T M A E ++ VK LL G+
Sbjct: 808 GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSD 867
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N +D + L+ + + + E LL + A ++ G +H A R V
Sbjct: 868 INIRDNEENICLHWAAFSGCVDI-AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVL 926
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
L +D+ +N G TPL ++N+Q A Q+
Sbjct: 927 FLSRDSDVTLKNKEGETPLQCASLNSQVWSALQM 960
>AL590627-3|CAI17355.1| 1267|Homo sapiens euchromatic histone-lysine
N-methyltransferase 1 protein.
Length = 1267
Score = 89.8 bits (213), Expect = 2e-17
Identities = 68/243 (27%), Positives = 103/243 (42%), Gaps = 2/243 (0%)
Query: 58 MLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAG 117
++ LD + K L R + ++ G++ K+ G+DPNF + + AA
Sbjct: 693 LIALDSEKPKKL--RFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAA 750
Query: 118 LKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLT 177
I LV GA +D + D T + A E N LEAVK L++ GA + KD +G T
Sbjct: 751 EAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGST 810
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNA 237
L+L+ ++ L + + D GW + A V V LL G+D+N
Sbjct: 811 CLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINI 870
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
R+ N LH A + A LL CD A+N +P +A D + +
Sbjct: 871 RDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR 930
Query: 298 KSD 300
SD
Sbjct: 931 DSD 933
Score = 74.9 bits (176), Expect = 6e-13
Identities = 57/180 (31%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
C E TPL AA + + + L+ GAL+D + +GST +H A +K E V+ LL
Sbjct: 771 CSEDQRTPLMEAAE-NNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 829
Query: 164 LGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLV 222
G N +D G TP+ + K L+ + LL + I D + +H A +G V
Sbjct: 830 NGQMDVNCQDDGGWTPMIWATEYKHVDLV-KLLLSKGSDINIRDNEENICLHWAAFSGCV 888
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ LL D++A N G++PLH+ A + C L R D N +TP Q A
Sbjct: 889 DIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 948
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 1/154 (0%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA + L NG ++ + G T M A E ++ VK LL G+
Sbjct: 808 GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSD 867
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N +D + L+ + + + E LL + A ++ G +H A R V
Sbjct: 868 INIRDNEENICLHWAAFSGCVDI-AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVL 926
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
L +D+ +N G TPL ++N+Q A Q+
Sbjct: 927 FLSRDSDVTLKNKEGETPLQCASLNSQVWSALQM 960
>AB058779-1|BAB47505.2| 803|Homo sapiens KIAA1876 protein protein.
Length = 803
Score = 89.8 bits (213), Expect = 2e-17
Identities = 68/243 (27%), Positives = 103/243 (42%), Gaps = 2/243 (0%)
Query: 58 MLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAG 117
++ LD + K L R + ++ G++ K+ G+DPNF + + AA
Sbjct: 343 LIALDSEKPKKL--RFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAA 400
Query: 118 LKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLT 177
I LV GA +D + D T + A E N LEAVK L++ GA + KD +G T
Sbjct: 401 EAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGST 460
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNA 237
L+L+ ++ L + + D GW + A V V LL G+D+N
Sbjct: 461 CLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINI 520
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
R+ N LH A + A LL CD A+N +P +A D + +
Sbjct: 521 RDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR 580
Query: 298 KSD 300
SD
Sbjct: 581 DSD 583
Score = 74.9 bits (176), Expect = 6e-13
Identities = 57/180 (31%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
C E TPL AA + + + L+ GAL+D + +GST +H A +K E V+ LL
Sbjct: 421 CSEDQRTPLMEAAE-NNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 479
Query: 164 LGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLV 222
G N +D G TP+ + K L+ + LL + I D + +H A +G V
Sbjct: 480 NGQMDVNCQDDGGWTPMIWATEYKHVDLV-KLLLSKGSDINIRDNEENICLHWAAFSGCV 538
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ LL D++A N G++PLH+ A + C L R D N +TP Q A
Sbjct: 539 DIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 598
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 1/154 (0%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA + L NG ++ + G T M A E ++ VK LL G+
Sbjct: 458 GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSD 517
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N +D + L+ + + + E LL + A ++ G +H A R V
Sbjct: 518 INIRDNEENICLHWAAFSGCVDI-AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVL 576
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
L +D+ +N G TPL ++N+Q A Q+
Sbjct: 577 FLSRDSDVTLKNKEGETPLQCASLNSQVWSALQM 610
>AB028932-1|BAB56104.1| 917|Homo sapiens GLP1 protein.
Length = 917
Score = 89.8 bits (213), Expect = 2e-17
Identities = 68/243 (27%), Positives = 103/243 (42%), Gaps = 2/243 (0%)
Query: 58 MLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAG 117
++ LD + K L R + ++ G++ K+ G+DPNF + + AA
Sbjct: 343 LIALDSEKPKKL--RFHPKQLYFSARQGELQKVLLMLVDGIDPNFKMEHQNKRSPLHAAA 400
Query: 118 LKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLT 177
I LV GA +D + D T + A E N LEAVK L++ GA + KD +G T
Sbjct: 401 EAGHVDICHMLVQAGANIDTCSEDQRTPLMEAAENNHLEAVKYLIKAGALVDPKDAEGST 460
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNA 237
L+L+ ++ L + + D GW + A V V LL G+D+N
Sbjct: 461 CLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSDINI 520
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
R+ N LH A + A LL CD A+N +P +A D + +
Sbjct: 521 RDNEENICLHWAAFSGCVDIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSR 580
Query: 298 KSD 300
SD
Sbjct: 581 DSD 583
Score = 74.9 bits (176), Expect = 6e-13
Identities = 57/180 (31%), Positives = 84/180 (46%), Gaps = 3/180 (1%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
C E TPL AA + + + L+ GAL+D + +GST +H A +K E V+ LL
Sbjct: 421 CSEDQRTPLMEAAE-NNHLEAVKYLIKAGALVDPKDAEGSTCLHLAAKKGHYEVVQYLLS 479
Query: 164 LGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLV 222
G N +D G TP+ + K L+ + LL + I D + +H A +G V
Sbjct: 480 NGQMDVNCQDDGGWTPMIWATEYKHVDLV-KLLLSKGSDINIRDNEENICLHWAAFSGCV 538
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ LL D++A N G++PLH+ A + C L R D N +TP Q A
Sbjct: 539 DIAEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVLFLSRDSDVTLKNKEGETPLQCA 598
Score = 46.8 bits (106), Expect = 2e-04
Identities = 41/154 (26%), Positives = 66/154 (42%), Gaps = 1/154 (0%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA + L NG ++ + G T M A E ++ VK LL G+
Sbjct: 458 GSTCLHLAAKKGHYEVVQYLLSNGQMDVNCQDDGGWTPMIWATEYKHVDLVKLLLSKGSD 517
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N +D + L+ + + + E LL + A ++ G +H A R V
Sbjct: 518 INIRDNEENICLHWAAFSGCVDI-AEILLAAKCDLHAVNIHGDSPLHIAARENRYDCVVL 576
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
L +D+ +N G TPL ++N+Q A Q+
Sbjct: 577 FLSRDSDVTLKNKEGETPLQCASLNSQVWSALQM 610
>AK098479-1|BAC05314.1| 353|Homo sapiens protein ( Homo sapiens
cDNA FLJ25613 fis, clone STM01546. ).
Length = 353
Score = 87.0 bits (206), Expect = 1e-16
Identities = 60/179 (33%), Positives = 91/179 (50%), Gaps = 2/179 (1%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
+TPL +AA ++ K AL + L+ R G +A+H AV LE V LL GAS
Sbjct: 126 QTPLHVAAANRA-TKCAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASL 184
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N D K PL+ + +L + L+ A +G D +G+ +H A +G ++ V +L
Sbjct: 185 NVCDKKERQPLHWAAFLGHLEVL-KLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYL 243
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
L GA+++ NA GNT LH+ QD+ A +L+ G + N TP VA ++ N
Sbjct: 244 LRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTN 302
Score = 52.8 bits (121), Expect = 3e-06
Identities = 42/135 (31%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+N GA L+ + +H A LE +K L+ GA KD KG L+ + +
Sbjct: 177 LLNKGASLNVCDKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQ 236
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
++ + LL A I + G +H AC G L+ GA++N N G TPLH
Sbjct: 237 IEVV-KYLLRMGAEIDEPNAFGNTALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLH 295
Query: 248 VCAVNAQDSCARQLL 262
V AV+ + +LL
Sbjct: 296 VAAVSTNGALCLELL 310
Score = 50.0 bits (114), Expect = 2e-05
Identities = 41/176 (23%), Positives = 73/176 (41%), Gaps = 2/176 (1%)
Query: 120 SPAKILIA-LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTP 178
SP I I + GA ++ + +HRA + + + LL A N +D TP
Sbjct: 69 SPPSIKIGNYIPTGANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTP 128
Query: 179 LYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
L+++ N+ E L +++ D G +H A +G ++ V+ LL GA +N
Sbjct: 129 LHVAAANRATK-CAEALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLNKGASLNVC 187
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ PLH A + L+ RG D + A +G +++ + +
Sbjct: 188 DKKERQPLHWAAFLGHLEVLKLLVARGADLGCKDRKGYGLLHTAAASGQIEVVKYL 243
Score = 42.7 bits (96), Expect = 0.003
Identities = 27/97 (27%), Positives = 45/97 (46%)
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + A D +H+A + + + LL + AD+NAR+ TPLHV A N CA
Sbjct: 83 ANVNAKDTLWLAPLHRAAASRNEKVLGLLLAHSADVNARDKLWQTPLHVAAANRATKCAE 142
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
L + + ++ AV +G+L+ ++ N
Sbjct: 143 ALAPLLSSLNVADRSGRSALHHAVHSGHLETVNLLLN 179
Score = 41.9 bits (94), Expect = 0.005
Identities = 29/116 (25%), Positives = 52/116 (44%), Gaps = 2/116 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ + A+G D C++ L A +++ L+ GA +D G+T
Sbjct: 202 GHLEVLKLLVARGAD--LGCKDRKGYGLLHTAAASGQIEVVKYLLRMGAEIDEPNAFGNT 259
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
A+H A L+ GA+ N + KG TPL+++ + L E L+++ A
Sbjct: 260 ALHIACYLGQDAVAIELVNAGANVNQPNDKGFTPLHVAAVSTNGALCLELLVNNGA 315
>BC101276-1|AAI01277.1| 420|Homo sapiens ANKDD1A protein protein.
Length = 420
Score = 85.0 bits (201), Expect = 6e-16
Identities = 62/211 (29%), Positives = 101/211 (47%), Gaps = 3/211 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HGQ+D + G D N +E G T L +AAG + +L LV+ G L+ + +G
Sbjct: 75 HGQLDALDFLVGSGCDHNVKDKE-GNTALHLAAG-RGHMAVLQRLVDIGLDLEEQNAEGL 132
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
TA+H A + + V+ LL G++ N K L+ L+ + + ++ + L+H
Sbjct: 133 TALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDV-SRVLIHAGGCAN 191
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D QG +H A R+ V L+ +D+NA + TPLH+ A +A A LL
Sbjct: 192 VVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLI 251
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
G D + +T VAV + ++ L ++I
Sbjct: 252 AGVDLNLRDEQGKTALAVAVRSNHVSLVDMI 282
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/175 (26%), Positives = 81/175 (46%), Gaps = 5/175 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE--LGASPNYKDGKGLTPLY 180
+IL LVN GA + ++DG T +H A +K + + ++E + ++ D G T +
Sbjct: 11 RILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFH 70
Query: 181 LSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN 239
+ + + D L + L+ D +G +H A G + + L+ G D+ +N
Sbjct: 71 RAAEHGQLDAL--DFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQN 128
Query: 240 ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
A G T LH A + C + LL G AL N + A ++G+ D++ V+
Sbjct: 129 AEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVL 183
Score = 60.5 bits (140), Expect = 1e-08
Identities = 49/200 (24%), Positives = 83/200 (41%), Gaps = 3/200 (1%)
Query: 103 HCQETGETPLTIAAGLKSPAKILIALVNG--GALLDYRTRDGSTAMHRAVEKNSLEAVKT 160
HC+ L A K +L ++ LD+ + G TA HRA E L+A+
Sbjct: 24 HCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDF 83
Query: 161 LLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG 220
L+ G N KD +G T L+L+ + + + L+ + + +G +H A
Sbjct: 84 LVGSGCDHNVKDKEGNTALHLA-AGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGS 142
Query: 221 LVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQ 280
V LL G+ +NA + LH A++ + +R L+ G ++ +P
Sbjct: 143 HPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLH 202
Query: 281 VAVIAGNLDLAEVIKNYKSD 300
+AV L ++ N SD
Sbjct: 203 LAVRHNFPALVRLLINSDSD 222
Score = 47.6 bits (108), Expect = 1e-04
Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 3/142 (2%)
Query: 155 LEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETL--LHDHATIGATDLQGWQE 212
L ++ L+ GA + + GLT L+ + P+L + L D A + D G
Sbjct: 10 LRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVA-LDHVDKLGRTA 68
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
H+A +G + +D L+ G D N ++ GNT LH+ A + ++L+ G D E N
Sbjct: 69 FHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQN 128
Query: 273 FANQTPYQVAVIAGNLDLAEVI 294
T A + D +++
Sbjct: 129 AEGLTALHSAAGGSHPDCVQLL 150
>BC101275-1|AAI01276.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 85.0 bits (201), Expect = 6e-16
Identities = 62/211 (29%), Positives = 101/211 (47%), Gaps = 3/211 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HGQ+D + G D N +E G T L +AAG + +L LV+ G L+ + +G
Sbjct: 78 HGQLDALDFLVGSGCDHNVKDKE-GNTALHLAAG-RGHMAVLQRLVDIGLDLEEQNAEGL 135
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
TA+H A + + V+ LL G++ N K L+ L+ + + ++ + L+H
Sbjct: 136 TALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDV-SRVLIHAGGCAN 194
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D QG +H A R+ V L+ +D+NA + TPLH+ A +A A LL
Sbjct: 195 VVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLI 254
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
G D + +T VAV + ++ L ++I
Sbjct: 255 AGVDLNLRDKQGKTALAVAVRSNHVSLVDMI 285
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/175 (26%), Positives = 81/175 (46%), Gaps = 5/175 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE--LGASPNYKDGKGLTPLY 180
+IL LVN GA + ++DG T +H A +K + + ++E + ++ D G T +
Sbjct: 14 RILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFH 73
Query: 181 LSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN 239
+ + + D L + L+ D +G +H A G + + L+ G D+ +N
Sbjct: 74 RAAEHGQLDAL--DFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQN 131
Query: 240 ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
A G T LH A + C + LL G AL N + A ++G+ D++ V+
Sbjct: 132 AEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVL 186
Score = 60.5 bits (140), Expect = 1e-08
Identities = 49/200 (24%), Positives = 83/200 (41%), Gaps = 3/200 (1%)
Query: 103 HCQETGETPLTIAAGLKSPAKILIALVNG--GALLDYRTRDGSTAMHRAVEKNSLEAVKT 160
HC+ L A K +L ++ LD+ + G TA HRA E L+A+
Sbjct: 27 HCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDF 86
Query: 161 LLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG 220
L+ G N KD +G T L+L+ + + + L+ + + +G +H A
Sbjct: 87 LVGSGCDHNVKDKEGNTALHLA-AGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGS 145
Query: 221 LVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQ 280
V LL G+ +NA + LH A++ + +R L+ G ++ +P
Sbjct: 146 HPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLH 205
Query: 281 VAVIAGNLDLAEVIKNYKSD 300
+AV L ++ N SD
Sbjct: 206 LAVRHNFPALVRLLINSDSD 225
Score = 47.6 bits (108), Expect = 1e-04
Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 3/142 (2%)
Query: 155 LEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETL--LHDHATIGATDLQGWQE 212
L ++ L+ GA + + GLT L+ + P+L + L D A + D G
Sbjct: 13 LRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVA-LDHVDKLGRTA 71
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
H+A +G + +D L+ G D N ++ GNT LH+ A + ++L+ G D E N
Sbjct: 72 FHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQN 131
Query: 273 FANQTPYQVAVIAGNLDLAEVI 294
T A + D +++
Sbjct: 132 AEGLTALHSAAGGSHPDCVQLL 153
>BC101274-1|AAI01275.1| 423|Homo sapiens ANKDD1A protein protein.
Length = 423
Score = 85.0 bits (201), Expect = 6e-16
Identities = 62/211 (29%), Positives = 101/211 (47%), Gaps = 3/211 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HGQ+D + G D N +E G T L +AAG + +L LV+ G L+ + +G
Sbjct: 78 HGQLDALDFLVGSGCDHNVKDKE-GNTALHLAAG-RGHMAVLQRLVDIGLDLEEQNAEGL 135
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
TA+H A + + V+ LL G++ N K L+ L+ + + ++ + L+H
Sbjct: 136 TALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDV-SRVLIHAGGCAN 194
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D QG +H A R+ V L+ +D+NA + TPLH+ A +A A LL
Sbjct: 195 VVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLI 254
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
G D + +T VAV + ++ L ++I
Sbjct: 255 AGVDLNLRDEQGKTALAVAVRSNHVSLVDMI 285
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/175 (26%), Positives = 81/175 (46%), Gaps = 5/175 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE--LGASPNYKDGKGLTPLY 180
+IL LVN GA + ++DG T +H A +K + + ++E + ++ D G T +
Sbjct: 14 RILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFH 73
Query: 181 LSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN 239
+ + + D L + L+ D +G +H A G + + L+ G D+ +N
Sbjct: 74 RAAEHGQLDAL--DFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQN 131
Query: 240 ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
A G T LH A + C + LL G AL N + A ++G+ D++ V+
Sbjct: 132 AEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVL 186
Score = 60.5 bits (140), Expect = 1e-08
Identities = 49/200 (24%), Positives = 83/200 (41%), Gaps = 3/200 (1%)
Query: 103 HCQETGETPLTIAAGLKSPAKILIALVNG--GALLDYRTRDGSTAMHRAVEKNSLEAVKT 160
HC+ L A K +L ++ LD+ + G TA HRA E L+A+
Sbjct: 27 HCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDF 86
Query: 161 LLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG 220
L+ G N KD +G T L+L+ + + + L+ + + +G +H A
Sbjct: 87 LVGSGCDHNVKDKEGNTALHLA-AGRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGS 145
Query: 221 LVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQ 280
V LL G+ +NA + LH A++ + +R L+ G ++ +P
Sbjct: 146 HPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLH 205
Query: 281 VAVIAGNLDLAEVIKNYKSD 300
+AV L ++ N SD
Sbjct: 206 LAVRHNFPALVRLLINSDSD 225
Score = 47.6 bits (108), Expect = 1e-04
Identities = 37/142 (26%), Positives = 63/142 (44%), Gaps = 3/142 (2%)
Query: 155 LEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETL--LHDHATIGATDLQGWQE 212
L ++ L+ GA + + GLT L+ + P+L + L D A + D G
Sbjct: 13 LRILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVA-LDHVDKLGRTA 71
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
H+A +G + +D L+ G D N ++ GNT LH+ A + ++L+ G D E N
Sbjct: 72 FHRAAEHGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQN 131
Query: 273 FANQTPYQVAVIAGNLDLAEVI 294
T A + D +++
Sbjct: 132 AEGLTALHSAAGGSHPDCVQLL 153
>BC034982-1|AAH34982.1| 909|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 909
Score = 84.2 bits (199), Expect = 1e-15
Identities = 63/200 (31%), Positives = 93/200 (46%), Gaps = 5/200 (2%)
Query: 99 DPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
D N+ + L IAA S + L+ L+ GA +Y+ G T +H A + +
Sbjct: 56 DVNYAFGRVKRSLLHIAANCGS-VECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCM 114
Query: 159 KTLLELGASPNYKDGKGLTPLY-LSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQAC 217
LLE A N + +GLT ++ L+V +T+ L L+ + + D G +H AC
Sbjct: 115 SKLLEYSADVNICNNEGLTAIHWLAVNGRTE--LLHDLVQHVSDVDVEDAMGQTALHVAC 172
Query: 218 RNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQT 277
+NG V LL GAD+N N SG TPL+ + Q A+ LL RG K + T
Sbjct: 173 QNGHKTTVQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVT 231
Query: 278 PYQVAVIAGNLDLAEVIKNY 297
P + V G + EV+ Y
Sbjct: 232 PLDLCVQGGYGETCEVLIQY 251
Score = 46.4 bits (105), Expect = 2e-04
Identities = 31/106 (29%), Positives = 46/106 (43%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL A D+ G +H A RNG + + LL Y AD+N N G T +H AVN +
Sbjct: 84 LLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICNNEGLTAIHWLAVNGR 143
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L+ D + + QT VA G+ + + + +D
Sbjct: 144 TELLHDLVQHVSDVDVEDAMGQTALHVACQNGHKTTVQCLLDSGAD 189
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/88 (31%), Positives = 40/88 (45%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A G V+ + LL GA+ N ++ SG TPLH+ A N Q C +LL D N
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNYKSD 300
T + G +L + + SD
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSD 156
>U50133-1|AAB47805.1| 1856|Homo sapiens ankyrin protein.
Length = 1856
Score = 83.0 bits (196), Expect = 2e-15
Identities = 74/237 (31%), Positives = 112/237 (47%), Gaps = 20/237 (8%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL G +DK G+D N C + G T L IAA L +++ LVN GA ++
Sbjct: 16 FLRAARSGNLDKALDHLRNGVDINT-CNQKGNTALHIAA-LAGQDEVVRELVNYGANVNA 73
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
+++ G T ++ A ++N LE VK LLE GA+ N G TPL +++ + ++ L
Sbjct: 74 QSQKGFTPLYMAAQENHLEVVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAH--LI 131
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
++ T G L +H A RN + LL + + + +G TPLH+ A +
Sbjct: 132 NYGTKGKVRLPA---LHIAARNDDTRTAAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNV 188
Query: 258 ARQLLFRGCDKEALNFANQ---TPYQVAVIAGN-------LDLAEVIKNYKSDEIVP 304
A+ LL RG ++NF Q TP +A GN LD I+ DE+ P
Sbjct: 189 AQLLLNRGA---SVNFTPQNGITPLHIASRRGNVIMVRLLLDRGAQIETKTKDELTP 242
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/214 (27%), Positives = 96/214 (44%), Gaps = 3/214 (1%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V H +D + +G P+ G TPL IAA ++ ++ +L+ G + +
Sbjct: 544 VHHNNLDIVKLLLPRGGSPHSPAWN-GYTPLHIAAK-QNQVEVARSLLQYGGSANAESVQ 601
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T +H A ++ E V LL A+ N + GLTPL+L P+ + L+
Sbjct: 602 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPV-ADVLIKHGVM 660
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ AT G+ +H A G ++ V LL + AD+NA+ G +PLH A L
Sbjct: 661 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 720
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIK 295
L G ++ TP +A G + + +V+K
Sbjct: 721 LKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLK 754
Score = 81.4 bits (192), Expect = 7e-15
Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 2/193 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A + ++G T +H AV N+L+ VK LL G S
Sbjct: 503 GFTPLHVAAKY-GKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGS 561
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ + + +LL + A +QG +H A + G + V
Sbjct: 562 PHSPAWNGYTPLHIAA-KQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVAL 620
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A+ N N SG TPLH+ A A L+ G +A TP VA GN
Sbjct: 621 LLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGN 680
Query: 288 LDLAEVIKNYKSD 300
+ L + + +++D
Sbjct: 681 IKLVKFLLQHQAD 693
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/190 (28%), Positives = 95/190 (50%), Gaps = 2/190 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL AA +I L++ GA + +T++G + +H A + + L+ V+ LL+ A +
Sbjct: 241 TPLHCAAR-NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 299
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
LTPL+++ + + + LL A + L G+ +H AC+ V+ ++ LL
Sbjct: 300 DITLDHLTPLHVAA-HCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 358
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
GA ++A SG TPLHV + + LL RG N +TP +A AG+ +
Sbjct: 359 KTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE 418
Query: 290 LAEVIKNYKS 299
+A+ + K+
Sbjct: 419 VAKYLLQNKA 428
Score = 70.9 bits (166), Expect = 1e-11
Identities = 57/214 (26%), Positives = 93/214 (43%), Gaps = 5/214 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G + + +G PN + ETPL +AA ++ L+ A ++ + +D T
Sbjct: 382 GHLPIVKNLLQRGASPNVSNVKV-ETPLHMAARA-GHTEVAKYLLQNKAKVNAKAKDDQT 439
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIG 203
+H A VK LLE A+PN G TPL+++ + +L LL A+
Sbjct: 440 PLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLA--LLEKEASQA 497
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
+G+ +H A + G V+ + LL A NA +G TPLHV + + LL
Sbjct: 498 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLP 557
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RG + + TP +A +++A + Y
Sbjct: 558 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQY 591
Score = 68.1 bits (159), Expect = 7e-11
Identities = 51/167 (30%), Positives = 73/167 (43%), Gaps = 1/167 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ A +D T D T +H A K LL+ GA PN + G TPL+++ K
Sbjct: 291 LLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIAC-KKN 349
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ E LL A+I A G +H A G + V +LL GA N N TPLH
Sbjct: 350 HVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 409
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ A A+ LL A +QTP A G+ ++ +++
Sbjct: 410 MAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 456
Score = 62.9 bits (146), Expect = 3e-09
Identities = 56/189 (29%), Positives = 79/189 (41%), Gaps = 2/189 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TPL +A+ + I+ L+ GA + T +H A E K LL+
Sbjct: 369 ESGLTPLHVASFM-GHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 427
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A N K TPL+ + ++ + LL ++A G +H A R G V+ V
Sbjct: 428 AKVNAKAKDDQTPLHCAARIGHTNMV-KLLLENNANPNLATTAGHTPLHIAAREGHVETV 486
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL A G TPLHV A + A LL R A TP VAV
Sbjct: 487 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHH 546
Query: 286 GNLDLAEVI 294
NLD+ +++
Sbjct: 547 NNLDIVKLL 555
Score = 58.8 bits (136), Expect = 4e-08
Identities = 50/195 (25%), Positives = 82/195 (42%), Gaps = 6/195 (3%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E G TPL +A + ++ L+N G R A+H A + LL+
Sbjct: 109 EDGFTPLAVALQ-QGHENVVAHLINYGTKGKVRL----PALHIAARNDDTRTAAVLLQND 163
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+P+ G TPL+++ + + + + LL+ A++ T G +H A R G V V
Sbjct: 164 PNPDVLSKTGFTPLHIAA-HYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMV 222
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA + + TPLH A N + LL G +A +P +A
Sbjct: 223 RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQG 282
Query: 286 GNLDLAEVIKNYKSD 300
+LD ++ Y ++
Sbjct: 283 DHLDCVRLLLQYDAE 297
>X16609-2|CAA34611.1| 1719|Homo sapiens alt. ankyrin (variant 2.2)
protein.
Length = 1719
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/214 (27%), Positives = 96/214 (44%), Gaps = 3/214 (1%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V H +D + +G P+ G TPL IAA ++ ++ +L+ G + +
Sbjct: 577 VHHNNLDIVKLLLPRGGSPHSPAWN-GYTPLHIAAK-QNQVEVARSLLQYGGSANAESVQ 634
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T +H A ++ E V LL A+ N + GLTPL+L P+ + L+
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPV-ADVLIKHGVM 693
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ AT G+ +H A G ++ V LL + AD+NA+ G +PLH A L
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIK 295
L G ++ TP +A G + + +V+K
Sbjct: 754 LKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLK 787
Score = 81.4 bits (192), Expect = 7e-15
Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 2/193 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A + ++G T +H AV N+L+ VK LL G S
Sbjct: 536 GFTPLHVAAKY-GKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGS 594
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ + + +LL + A +QG +H A + G + V
Sbjct: 595 PHSPAWNGYTPLHIAA-KQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVAL 653
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A+ N N SG TPLH+ A A L+ G +A TP VA GN
Sbjct: 654 LLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGN 713
Query: 288 LDLAEVIKNYKSD 300
+ L + + +++D
Sbjct: 714 IKLVKFLLQHQAD 726
Score = 78.2 bits (184), Expect = 7e-14
Identities = 60/219 (27%), Positives = 101/219 (46%), Gaps = 7/219 (3%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL G +DK G+D N C + G L +A+ + K+++ L++ +L+
Sbjct: 16 FLRAARSGNLDKALDHLRNGVDINT-CNQNGLNGLHLASK-EGHVKMVVELLHKEIILET 73
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
T+ G+TA+H A E V+ L+ GA+ N + KG TPLY++ + + + LL
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMA-AQENHLEVVKFLLE 132
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+ A G+ + A + G V HL+ YG R + LH+ A N
Sbjct: 133 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPA----LHIAARNDDTRT 188
Query: 258 ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
A LL + + L+ TP +A NL++A+++ N
Sbjct: 189 AAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN 227
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/190 (28%), Positives = 95/190 (50%), Gaps = 2/190 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL AA +I L++ GA + +T++G + +H A + + L+ V+ LL+ A +
Sbjct: 274 TPLHCAAR-NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
LTPL+++ + + + LL A + L G+ +H AC+ V+ ++ LL
Sbjct: 333 DITLDHLTPLHVAA-HCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
GA ++A SG TPLHV + + LL RG N +TP +A AG+ +
Sbjct: 392 KTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE 451
Query: 290 LAEVIKNYKS 299
+A+ + K+
Sbjct: 452 VAKYLLQNKA 461
Score = 70.9 bits (166), Expect = 1e-11
Identities = 57/214 (26%), Positives = 93/214 (43%), Gaps = 5/214 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G + + +G PN + ETPL +AA ++ L+ A ++ + +D T
Sbjct: 415 GHLPIVKNLLQRGASPNVSNVKV-ETPLHMAARA-GHTEVAKYLLQNKAKVNAKAKDDQT 472
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIG 203
+H A VK LLE A+PN G TPL+++ + +L LL A+
Sbjct: 473 PLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLA--LLEKEASQA 530
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
+G+ +H A + G V+ + LL A NA +G TPLHV + + LL
Sbjct: 531 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLP 590
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RG + + TP +A +++A + Y
Sbjct: 591 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQY 624
Score = 70.5 bits (165), Expect = 1e-11
Identities = 65/207 (31%), Positives = 100/207 (48%), Gaps = 19/207 (9%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IAA L +++ LVN GA ++ +++ G T ++ A ++N LE VK LLE GA+
Sbjct: 78 GNTALHIAA-LAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N G TPL +++ + ++ L ++ T G L +H A RN +
Sbjct: 137 QNVATEDGFTPLAVALQQGHENVVAH--LINYGTKGKVRLPA---LHIAARNDDTRTAAV 191
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQ---TPYQVAVI 284
LL + + + +G TPLH+ A + A+ LL RG ++NF Q TP +A
Sbjct: 192 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGA---SVNFTPQNGITPLHIASR 248
Query: 285 AGN-------LDLAEVIKNYKSDEIVP 304
GN LD I+ DE+ P
Sbjct: 249 RGNVIMVRLLLDRGAQIETKTKDELTP 275
Score = 68.1 bits (159), Expect = 7e-11
Identities = 51/167 (30%), Positives = 73/167 (43%), Gaps = 1/167 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ A +D T D T +H A K LL+ GA PN + G TPL+++ K
Sbjct: 324 LLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIAC-KKN 382
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ E LL A+I A G +H A G + V +LL GA N N TPLH
Sbjct: 383 HVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 442
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ A A+ LL A +QTP A G+ ++ +++
Sbjct: 443 MAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Score = 62.9 bits (146), Expect = 3e-09
Identities = 56/189 (29%), Positives = 79/189 (41%), Gaps = 2/189 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TPL +A+ + I+ L+ GA + T +H A E K LL+
Sbjct: 402 ESGLTPLHVASFM-GHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A N K TPL+ + ++ + LL ++A G +H A R G V+ V
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHTNMV-KLLLENNANPNLATTAGHTPLHIAAREGHVETV 519
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL A G TPLHV A + A LL R A TP VAV
Sbjct: 520 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHH 579
Query: 286 GNLDLAEVI 294
NLD+ +++
Sbjct: 580 NNLDIVKLL 588
Score = 59.7 bits (138), Expect = 2e-08
Identities = 44/161 (27%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Query: 137 YRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLL 196
+R D +T+ RA +L+ L G N + GL L+L+ ++ E LL
Sbjct: 7 FREADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVE-LL 65
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDS 256
H + T +G +H A G + V L+ YGA++NA++ G TPL++ A
Sbjct: 66 HKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLE 125
Query: 257 CARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
+ LL G ++ TP VA+ G+ ++ + NY
Sbjct: 126 VVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 166
Score = 58.8 bits (136), Expect = 4e-08
Identities = 50/195 (25%), Positives = 82/195 (42%), Gaps = 6/195 (3%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E G TPL +A + ++ L+N G R A+H A + LL+
Sbjct: 142 EDGFTPLAVALQ-QGHENVVAHLINYGTKGKVRL----PALHIAARNDDTRTAAVLLQND 196
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+P+ G TPL+++ + + + + LL+ A++ T G +H A R G V V
Sbjct: 197 PNPDVLSKTGFTPLHIAA-HYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMV 255
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA + + TPLH A N + LL G +A +P +A
Sbjct: 256 RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQG 315
Query: 286 GNLDLAEVIKNYKSD 300
+LD ++ Y ++
Sbjct: 316 DHLDCVRLLLQYDAE 330
>X16609-1|CAA34610.1| 1881|Homo sapiens protein ( Human mRNA for
ankyrin (variant 2.1). ).
Length = 1881
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/214 (27%), Positives = 96/214 (44%), Gaps = 3/214 (1%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V H +D + +G P+ G TPL IAA ++ ++ +L+ G + +
Sbjct: 577 VHHNNLDIVKLLLPRGGSPHSPAWN-GYTPLHIAAK-QNQVEVARSLLQYGGSANAESVQ 634
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T +H A ++ E V LL A+ N + GLTPL+L P+ + L+
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPV-ADVLIKHGVM 693
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ AT G+ +H A G ++ V LL + AD+NA+ G +PLH A L
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIK 295
L G ++ TP +A G + + +V+K
Sbjct: 754 LKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLK 787
Score = 81.4 bits (192), Expect = 7e-15
Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 2/193 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A + ++G T +H AV N+L+ VK LL G S
Sbjct: 536 GFTPLHVAAKY-GKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGS 594
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ + + +LL + A +QG +H A + G + V
Sbjct: 595 PHSPAWNGYTPLHIAA-KQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVAL 653
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A+ N N SG TPLH+ A A L+ G +A TP VA GN
Sbjct: 654 LLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGN 713
Query: 288 LDLAEVIKNYKSD 300
+ L + + +++D
Sbjct: 714 IKLVKFLLQHQAD 726
Score = 78.2 bits (184), Expect = 7e-14
Identities = 60/219 (27%), Positives = 101/219 (46%), Gaps = 7/219 (3%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL G +DK G+D N C + G L +A+ + K+++ L++ +L+
Sbjct: 16 FLRAARSGNLDKALDHLRNGVDINT-CNQNGLNGLHLASK-EGHVKMVVELLHKEIILET 73
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
T+ G+TA+H A E V+ L+ GA+ N + KG TPLY++ + + + LL
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMA-AQENHLEVVKFLLE 132
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+ A G+ + A + G V HL+ YG R + LH+ A N
Sbjct: 133 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPA----LHIAARNDDTRT 188
Query: 258 ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
A LL + + L+ TP +A NL++A+++ N
Sbjct: 189 AAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN 227
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/190 (28%), Positives = 95/190 (50%), Gaps = 2/190 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL AA +I L++ GA + +T++G + +H A + + L+ V+ LL+ A +
Sbjct: 274 TPLHCAAR-NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
LTPL+++ + + + LL A + L G+ +H AC+ V+ ++ LL
Sbjct: 333 DITLDHLTPLHVAA-HCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
GA ++A SG TPLHV + + LL RG N +TP +A AG+ +
Sbjct: 392 KTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE 451
Query: 290 LAEVIKNYKS 299
+A+ + K+
Sbjct: 452 VAKYLLQNKA 461
Score = 70.9 bits (166), Expect = 1e-11
Identities = 57/214 (26%), Positives = 93/214 (43%), Gaps = 5/214 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G + + +G PN + ETPL +AA ++ L+ A ++ + +D T
Sbjct: 415 GHLPIVKNLLQRGASPNVSNVKV-ETPLHMAARA-GHTEVAKYLLQNKAKVNAKAKDDQT 472
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIG 203
+H A VK LLE A+PN G TPL+++ + +L LL A+
Sbjct: 473 PLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLA--LLEKEASQA 530
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
+G+ +H A + G V+ + LL A NA +G TPLHV + + LL
Sbjct: 531 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLP 590
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RG + + TP +A +++A + Y
Sbjct: 591 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQY 624
Score = 70.5 bits (165), Expect = 1e-11
Identities = 65/207 (31%), Positives = 100/207 (48%), Gaps = 19/207 (9%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IAA L +++ LVN GA ++ +++ G T ++ A ++N LE VK LLE GA+
Sbjct: 78 GNTALHIAA-LAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N G TPL +++ + ++ L ++ T G L +H A RN +
Sbjct: 137 QNVATEDGFTPLAVALQQGHENVVAH--LINYGTKGKVRLPA---LHIAARNDDTRTAAV 191
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQ---TPYQVAVI 284
LL + + + +G TPLH+ A + A+ LL RG ++NF Q TP +A
Sbjct: 192 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGA---SVNFTPQNGITPLHIASR 248
Query: 285 AGN-------LDLAEVIKNYKSDEIVP 304
GN LD I+ DE+ P
Sbjct: 249 RGNVIMVRLLLDRGAQIETKTKDELTP 275
Score = 68.1 bits (159), Expect = 7e-11
Identities = 51/167 (30%), Positives = 73/167 (43%), Gaps = 1/167 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ A +D T D T +H A K LL+ GA PN + G TPL+++ K
Sbjct: 324 LLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIAC-KKN 382
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ E LL A+I A G +H A G + V +LL GA N N TPLH
Sbjct: 383 HVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 442
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ A A+ LL A +QTP A G+ ++ +++
Sbjct: 443 MAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Score = 62.9 bits (146), Expect = 3e-09
Identities = 56/189 (29%), Positives = 79/189 (41%), Gaps = 2/189 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TPL +A+ + I+ L+ GA + T +H A E K LL+
Sbjct: 402 ESGLTPLHVASFM-GHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A N K TPL+ + ++ + LL ++A G +H A R G V+ V
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHTNMV-KLLLENNANPNLATTAGHTPLHIAAREGHVETV 519
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL A G TPLHV A + A LL R A TP VAV
Sbjct: 520 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHH 579
Query: 286 GNLDLAEVI 294
NLD+ +++
Sbjct: 580 NNLDIVKLL 588
Score = 59.7 bits (138), Expect = 2e-08
Identities = 44/161 (27%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Query: 137 YRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLL 196
+R D +T+ RA +L+ L G N + GL L+L+ ++ E LL
Sbjct: 7 FREADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVE-LL 65
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDS 256
H + T +G +H A G + V L+ YGA++NA++ G TPL++ A
Sbjct: 66 HKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLE 125
Query: 257 CARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
+ LL G ++ TP VA+ G+ ++ + NY
Sbjct: 126 VVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 166
Score = 58.8 bits (136), Expect = 4e-08
Identities = 50/195 (25%), Positives = 82/195 (42%), Gaps = 6/195 (3%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E G TPL +A + ++ L+N G R A+H A + LL+
Sbjct: 142 EDGFTPLAVALQ-QGHENVVAHLINYGTKGKVRL----PALHIAARNDDTRTAAVLLQND 196
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+P+ G TPL+++ + + + + LL+ A++ T G +H A R G V V
Sbjct: 197 PNPDVLSKTGFTPLHIAA-HYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMV 255
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA + + TPLH A N + LL G +A +P +A
Sbjct: 256 RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQG 315
Query: 286 GNLDLAEVIKNYKSD 300
+LD ++ Y ++
Sbjct: 316 DHLDCVRLLLQYDAE 330
>M28880-1|AAA51732.1| 1880|Homo sapiens ankyrin protein.
Length = 1880
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/214 (27%), Positives = 96/214 (44%), Gaps = 3/214 (1%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V H +D + +G P+ G TPL IAA ++ ++ +L+ G + +
Sbjct: 577 VHHNNLDIVKLLLPRGGSPHSPAWN-GYTPLHIAAK-QNQVEVARSLLQYGGSANAESVQ 634
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T +H A ++ E V LL A+ N + GLTPL+L P+ + L+
Sbjct: 635 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPV-ADVLIKHGVM 693
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ AT G+ +H A G ++ V LL + AD+NA+ G +PLH A L
Sbjct: 694 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 753
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIK 295
L G ++ TP +A G + + +V+K
Sbjct: 754 LKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLK 787
Score = 81.4 bits (192), Expect = 7e-15
Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 2/193 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A + ++G T +H AV N+L+ VK LL G S
Sbjct: 536 GFTPLHVAAKY-GKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGS 594
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ + + +LL + A +QG +H A + G + V
Sbjct: 595 PHSPAWNGYTPLHIAA-KQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVAL 653
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A+ N N SG TPLH+ A A L+ G +A TP VA GN
Sbjct: 654 LLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGN 713
Query: 288 LDLAEVIKNYKSD 300
+ L + + +++D
Sbjct: 714 IKLVKFLLQHQAD 726
Score = 78.2 bits (184), Expect = 7e-14
Identities = 60/219 (27%), Positives = 101/219 (46%), Gaps = 7/219 (3%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL G +DK G+D N C + G L +A+ + K+++ L++ +L+
Sbjct: 16 FLRAARSGNLDKALDHLRNGVDINT-CNQNGLNGLHLASK-EGHVKMVVELLHKEIILET 73
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
T+ G+TA+H A E V+ L+ GA+ N + KG TPLY++ + + + LL
Sbjct: 74 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMA-AQENHLEVVKFLLE 132
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+ A G+ + A + G V HL+ YG R + LH+ A N
Sbjct: 133 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPA----LHIAARNDDTRT 188
Query: 258 ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
A LL + + L+ TP +A NL++A+++ N
Sbjct: 189 AAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN 227
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/190 (28%), Positives = 95/190 (50%), Gaps = 2/190 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL AA +I L++ GA + +T++G + +H A + + L+ V+ LL+ A +
Sbjct: 274 TPLHCAAR-NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 332
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
LTPL+++ + + + LL A + L G+ +H AC+ V+ ++ LL
Sbjct: 333 DITLDHLTPLHVAA-HCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 391
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
GA ++A SG TPLHV + + LL RG N +TP +A AG+ +
Sbjct: 392 KTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE 451
Query: 290 LAEVIKNYKS 299
+A+ + K+
Sbjct: 452 VAKYLLQNKA 461
Score = 70.9 bits (166), Expect = 1e-11
Identities = 57/214 (26%), Positives = 93/214 (43%), Gaps = 5/214 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G + + +G PN + ETPL +AA ++ L+ A ++ + +D T
Sbjct: 415 GHLPIVKNLLQRGASPNVSNVKV-ETPLHMAARA-GHTEVAKYLLQNKAKVNAKAKDDQT 472
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIG 203
+H A VK LLE A+PN G TPL+++ + +L LL A+
Sbjct: 473 PLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLA--LLEKEASQA 530
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
+G+ +H A + G V+ + LL A NA +G TPLHV + + LL
Sbjct: 531 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLP 590
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RG + + TP +A +++A + Y
Sbjct: 591 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQY 624
Score = 70.5 bits (165), Expect = 1e-11
Identities = 65/207 (31%), Positives = 100/207 (48%), Gaps = 19/207 (9%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IAA L +++ LVN GA ++ +++ G T ++ A ++N LE VK LLE GA+
Sbjct: 78 GNTALHIAA-LAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 136
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N G TPL +++ + ++ L ++ T G L +H A RN +
Sbjct: 137 QNVATEDGFTPLAVALQQGHENVVAH--LINYGTKGKVRLPA---LHIAARNDDTRTAAV 191
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQ---TPYQVAVI 284
LL + + + +G TPLH+ A + A+ LL RG ++NF Q TP +A
Sbjct: 192 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRG---SSVNFTPQNGITPLHIASR 248
Query: 285 AGN-------LDLAEVIKNYKSDEIVP 304
GN LD I+ DE+ P
Sbjct: 249 RGNVIMVRLLLDRGAQIETKTKDELTP 275
Score = 68.1 bits (159), Expect = 7e-11
Identities = 51/167 (30%), Positives = 73/167 (43%), Gaps = 1/167 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ A +D T D T +H A K LL+ GA PN + G TPL+++ K
Sbjct: 324 LLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIAC-KKN 382
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ E LL A+I A G +H A G + V +LL GA N N TPLH
Sbjct: 383 HVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 442
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ A A+ LL A +QTP A G+ ++ +++
Sbjct: 443 MAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 489
Score = 62.9 bits (146), Expect = 3e-09
Identities = 56/189 (29%), Positives = 79/189 (41%), Gaps = 2/189 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TPL +A+ + I+ L+ GA + T +H A E K LL+
Sbjct: 402 ESGLTPLHVASFM-GHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 460
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A N K TPL+ + ++ + LL ++A G +H A R G V+ V
Sbjct: 461 AKVNAKAKDDQTPLHCAARIGHTNMV-KLLLENNANPNLATTAGHTPLHIAAREGHVETV 519
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL A G TPLHV A + A LL R A TP VAV
Sbjct: 520 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHH 579
Query: 286 GNLDLAEVI 294
NLD+ +++
Sbjct: 580 NNLDIVKLL 588
Score = 59.7 bits (138), Expect = 2e-08
Identities = 44/161 (27%), Positives = 73/161 (45%), Gaps = 1/161 (0%)
Query: 137 YRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLL 196
+R D +T+ RA +L+ L G N + GL L+L+ ++ E LL
Sbjct: 7 FREADAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVE-LL 65
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDS 256
H + T +G +H A G + V L+ YGA++NA++ G TPL++ A
Sbjct: 66 HKEIILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLE 125
Query: 257 CARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
+ LL G ++ TP VA+ G+ ++ + NY
Sbjct: 126 VVKFLLENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 166
Score = 57.6 bits (133), Expect = 1e-07
Identities = 49/195 (25%), Positives = 82/195 (42%), Gaps = 6/195 (3%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E G TPL +A + ++ L+N G R A+H A + LL+
Sbjct: 142 EDGFTPLAVALQ-QGHENVVAHLINYGTKGKVRL----PALHIAARNDDTRTAAVLLQND 196
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+P+ G TPL+++ + + + + LL+ +++ T G +H A R G V V
Sbjct: 197 PNPDVLSKTGFTPLHIAA-HYENLNVAQLLLNRGSSVNFTPQNGITPLHIASRRGNVIMV 255
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA + + TPLH A N + LL G +A +P +A
Sbjct: 256 RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQG 315
Query: 286 GNLDLAEVIKNYKSD 300
+LD ++ Y ++
Sbjct: 316 DHLDCVRLLLQYDAE 330
>AB209418-1|BAD92655.1| 1899|Homo sapiens ankyrin 1 isoform 4
variant protein.
Length = 1899
Score = 82.6 bits (195), Expect = 3e-15
Identities = 59/214 (27%), Positives = 96/214 (44%), Gaps = 3/214 (1%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V H +D + +G P+ G TPL IAA ++ ++ +L+ G + +
Sbjct: 612 VHHNNLDIVKLLLPRGGSPHSPAWN-GYTPLHIAAK-QNQVEVARSLLQYGGSANAESVQ 669
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T +H A ++ E V LL A+ N + GLTPL+L P+ + L+
Sbjct: 670 GVTPLHLAAQEGHAEMVALLLSKQANGNLGNKSGLTPLHLVAQEGHVPV-ADVLIKHGVM 728
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ AT G+ +H A G ++ V LL + AD+NA+ G +PLH A L
Sbjct: 729 VDATTRMGYTPLHVASHYGNIKLVKFLLQHQADVNAKTKLGYSPLHQAAQQGHTDIVTLL 788
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIK 295
L G ++ TP +A G + + +V+K
Sbjct: 789 LKNGASPNEVSSDGTTPLAIAKRLGYISVTDVLK 822
Score = 81.4 bits (192), Expect = 7e-15
Identities = 59/193 (30%), Positives = 91/193 (47%), Gaps = 2/193 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL +AA ++ L+ A + ++G T +H AV N+L+ VK LL G S
Sbjct: 571 GFTPLHVAAKY-GKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLPRGGS 629
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
P+ G TPL+++ + + +LL + A +QG +H A + G + V
Sbjct: 630 PHSPAWNGYTPLHIAA-KQNQVEVARSLLQYGGSANAESVQGVTPLHLAAQEGHAEMVAL 688
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL A+ N N SG TPLH+ A A L+ G +A TP VA GN
Sbjct: 689 LLSKQANGNLGNKSGLTPLHLVAQEGHVPVADVLIKHGVMVDATTRMGYTPLHVASHYGN 748
Query: 288 LDLAEVIKNYKSD 300
+ L + + +++D
Sbjct: 749 IKLVKFLLQHQAD 761
Score = 78.2 bits (184), Expect = 7e-14
Identities = 60/219 (27%), Positives = 101/219 (46%), Gaps = 7/219 (3%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL G +DK G+D N C + G L +A+ + K+++ L++ +L+
Sbjct: 51 FLRAARSGNLDKALDHLRNGVDINT-CNQNGLNGLHLASK-EGHVKMVVELLHKEIILET 108
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
T+ G+TA+H A E V+ L+ GA+ N + KG TPLY++ + + + LL
Sbjct: 109 TTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMA-AQENHLEVVKFLLE 167
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+ A G+ + A + G V HL+ YG R + LH+ A N
Sbjct: 168 NGANQNVATEDGFTPLAVALQQGHENVVAHLINYGTKGKVRLPA----LHIAARNDDTRT 223
Query: 258 ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
A LL + + L+ TP +A NL++A+++ N
Sbjct: 224 AAVLLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLN 262
Score = 77.0 bits (181), Expect = 2e-13
Identities = 55/190 (28%), Positives = 95/190 (50%), Gaps = 2/190 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL AA +I L++ GA + +T++G + +H A + + L+ V+ LL+ A +
Sbjct: 309 TPLHCAAR-NGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQGDHLDCVRLLLQYDAEID 367
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
LTPL+++ + + + LL A + L G+ +H AC+ V+ ++ LL
Sbjct: 368 DITLDHLTPLHVAA-HCGHHRVAKVLLDKGAKPNSRALNGFTPLHIACKKNHVRVMELLL 426
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
GA ++A SG TPLHV + + LL RG N +TP +A AG+ +
Sbjct: 427 KTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTE 486
Query: 290 LAEVIKNYKS 299
+A+ + K+
Sbjct: 487 VAKYLLQNKA 496
Score = 70.9 bits (166), Expect = 1e-11
Identities = 57/214 (26%), Positives = 93/214 (43%), Gaps = 5/214 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G + + +G PN + ETPL +AA ++ L+ A ++ + +D T
Sbjct: 450 GHLPIVKNLLQRGASPNVSNVKV-ETPLHMAARA-GHTEVAKYLLQNKAKVNAKAKDDQT 507
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIG 203
+H A VK LLE A+PN G TPL+++ + +L LL A+
Sbjct: 508 PLHCAARIGHTNMVKLLLENNANPNLATTAGHTPLHIAAREGHVETVLA--LLEKEASQA 565
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
+G+ +H A + G V+ + LL A NA +G TPLHV + + LL
Sbjct: 566 CMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHHNNLDIVKLLLP 625
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RG + + TP +A +++A + Y
Sbjct: 626 RGGSPHSPAWNGYTPLHIAAKQNQVEVARSLLQY 659
Score = 70.5 bits (165), Expect = 1e-11
Identities = 65/207 (31%), Positives = 100/207 (48%), Gaps = 19/207 (9%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IAA L +++ LVN GA ++ +++ G T ++ A ++N LE VK LLE GA+
Sbjct: 113 GNTALHIAA-LAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKFLLENGAN 171
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N G TPL +++ + ++ L ++ T G L +H A RN +
Sbjct: 172 QNVATEDGFTPLAVALQQGHENVVAH--LINYGTKGKVRLPA---LHIAARNDDTRTAAV 226
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQ---TPYQVAVI 284
LL + + + +G TPLH+ A + A+ LL RG ++NF Q TP +A
Sbjct: 227 LLQNDPNPDVLSKTGFTPLHIAAHYENLNVAQLLLNRGA---SVNFTPQNGITPLHIASR 283
Query: 285 AGN-------LDLAEVIKNYKSDEIVP 304
GN LD I+ DE+ P
Sbjct: 284 RGNVIMVRLLLDRGAQIETKTKDELTP 310
Score = 68.1 bits (159), Expect = 7e-11
Identities = 51/167 (30%), Positives = 73/167 (43%), Gaps = 1/167 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ A +D T D T +H A K LL+ GA PN + G TPL+++ K
Sbjct: 359 LLQYDAEIDDITLDHLTPLHVAAHCGHHRVAKVLLDKGAKPNSRALNGFTPLHIAC-KKN 417
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ E LL A+I A G +H A G + V +LL GA N N TPLH
Sbjct: 418 HVRVMELLLKTGASIDAVTESGLTPLHVASFMGHLPIVKNLLQRGASPNVSNVKVETPLH 477
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ A A+ LL A +QTP A G+ ++ +++
Sbjct: 478 MAARAGHTEVAKYLLQNKAKVNAKAKDDQTPLHCAARIGHTNMVKLL 524
Score = 62.9 bits (146), Expect = 3e-09
Identities = 56/189 (29%), Positives = 79/189 (41%), Gaps = 2/189 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TPL +A+ + I+ L+ GA + T +H A E K LL+
Sbjct: 437 ESGLTPLHVASFM-GHLPIVKNLLQRGASPNVSNVKVETPLHMAARAGHTEVAKYLLQNK 495
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
A N K TPL+ + ++ + LL ++A G +H A R G V+ V
Sbjct: 496 AKVNAKAKDDQTPLHCAARIGHTNMV-KLLLENNANPNLATTAGHTPLHIAAREGHVETV 554
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL A G TPLHV A + A LL R A TP VAV
Sbjct: 555 LALLEKEASQACMTKKGFTPLHVAAKYGKVRVAELLLERDAHPNAAGKNGLTPLHVAVHH 614
Query: 286 GNLDLAEVI 294
NLD+ +++
Sbjct: 615 NNLDIVKLL 623
Score = 58.8 bits (136), Expect = 4e-08
Identities = 50/195 (25%), Positives = 82/195 (42%), Gaps = 6/195 (3%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E G TPL +A + ++ L+N G R A+H A + LL+
Sbjct: 177 EDGFTPLAVALQ-QGHENVVAHLINYGTKGKVRL----PALHIAARNDDTRTAAVLLQND 231
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+P+ G TPL+++ + + + + LL+ A++ T G +H A R G V V
Sbjct: 232 PNPDVLSKTGFTPLHIAA-HYENLNVAQLLLNRGASVNFTPQNGITPLHIASRRGNVIMV 290
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA + + TPLH A N + LL G +A +P +A
Sbjct: 291 RLLLDRGAQIETKTKDELTPLHCAARNGHVRISEILLDHGAPIQAKTKNGLSPIHMAAQG 350
Query: 286 GNLDLAEVIKNYKSD 300
+LD ++ Y ++
Sbjct: 351 DHLDCVRLLLQYDAE 365
Score = 57.2 bits (132), Expect = 1e-07
Identities = 43/157 (27%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
D +T+ RA +L+ L G N + GL L+L+ ++ E LLH
Sbjct: 46 DAATSFLRAARSGNLDKALDHLRNGVDINTCNQNGLNGLHLASKEGHVKMVVE-LLHKEI 104
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
+ T +G +H A G + V L+ YGA++NA++ G TPL++ A +
Sbjct: 105 ILETTTKKGNTALHIAALAGQDEVVRELVNYGANVNAQSQKGFTPLYMAAQENHLEVVKF 164
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
LL G ++ TP VA+ G+ ++ + NY
Sbjct: 165 LLENGANQNVATEDGFTPLAVALQQGHENVVAHLINY 201
>AK125360-1|BAC86146.1| 588|Homo sapiens protein ( Homo sapiens
cDNA FLJ43370 fis, clone NTONG2005277, weakly similar
to ANKYRIN 1. ).
Length = 588
Score = 80.6 bits (190), Expect = 1e-14
Identities = 54/173 (31%), Positives = 84/173 (48%), Gaps = 1/173 (0%)
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L +++T DG T + AV+ +E V+TLLE G PN K+ KG TPL ++V K +
Sbjct: 103 LWEFKTCDGETPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLIAV-KKGSYDMVS 161
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
TL+ + ++ ++ W +H+A + G V LL +G +++ R+ G TPL V A
Sbjct: 162 TLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLGVAAEYG 221
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFR 306
L+ +G D AL + A GN D ++ Y VP R
Sbjct: 222 HCDVLEHLIHKGGDVLALADDGASVLFEAAGGGNPDCISLLLEYGGSGNVPNR 274
Score = 68.9 bits (161), Expect = 4e-11
Identities = 58/213 (27%), Positives = 91/213 (42%), Gaps = 4/213 (1%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V G ++ + KG+ PN + GETPL IA K ++ L+ LD
Sbjct: 119 VKAGLVENVRTLLEKGVWPNTK-NDKGETPLLIAVK-KGSYDMVSTLIKHNTSLDQPCVK 176
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
+AMH A ++ + V LL+ G + + +DG G+TPL ++ +L E L+H
Sbjct: 177 RWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLGVAAEYGHCDVL-EHLIHKGGD 235
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ A G + +A G + LL YG N N +G+ P+H A A +
Sbjct: 236 VLALADDGASVLFEAAGGGNPDCISLLLEYGGSGNVPNRAGHLPIHRAAYEGH-YLALKY 294
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
L K A+ + TP A N E++
Sbjct: 295 LIPVTSKNAIRKSGLTPIHSAADGQNAQCLELL 327
>BX640674-1|CAE45806.1| 1280|Homo sapiens hypothetical protein
protein.
Length = 1280
Score = 80.2 bits (189), Expect = 2e-14
Identities = 58/202 (28%), Positives = 96/202 (47%), Gaps = 5/202 (2%)
Query: 103 HCQETGETPLTIAA----GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
H G T L++AA K A ++ L++ GA +D+ +DG T + A + ++ V
Sbjct: 556 HEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVV 615
Query: 159 KTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACR 218
LLE GA ++ D G TPL L+ + + TLL A + + D +G + A
Sbjct: 616 DLLLEGGADVDHTDNNGRTPL-LAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASA 674
Query: 219 NGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
G V+ V LL G D N R+ +G TPLH+ A L+ +G ++ + P
Sbjct: 675 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIP 734
Query: 279 YQVAVIAGNLDLAEVIKNYKSD 300
+ +A G+ D +++ KS+
Sbjct: 735 FILASQEGHYDCVQILLENKSN 756
Score = 76.6 bits (180), Expect = 2e-13
Identities = 60/228 (26%), Positives = 102/228 (44%), Gaps = 9/228 (3%)
Query: 73 ANLRRFLEHVTH-GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNG 131
+N R L + + G +D + ++G D G TPLT+AA + K++ L+
Sbjct: 394 SNGRTLLANAAYSGSLDVVNLLVSRGADLEIE-DAHGHTPLTLAAR-QGHTKVVNCLIGC 451
Query: 132 GALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLL 191
GA +++ +DG TA+ A E V LL G + D T L + + ++
Sbjct: 452 GANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGHEDIV 511
Query: 192 CETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAV 251
L H A + D +G + A G + V+HLL +GA++N + G T L V A+
Sbjct: 512 LNLLQHG-AEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAAL 570
Query: 252 -----NAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
S L+ RG + + + TP VA G++D+ +++
Sbjct: 571 CVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLL 618
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/249 (28%), Positives = 112/249 (44%), Gaps = 36/249 (14%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G +D + G D + H G TPL AA + A ++ L+ GA +D +G T
Sbjct: 610 GHVDVVDLLLEGGADVD-HTDNNGRTPLLAAASM-GHASVVNTLLFWGAAVDSIDSEGRT 667
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+ A + ++E V+TLL+ G N++D G TPL+++ + L+CE L+ A
Sbjct: 668 VLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAF-EGHRLICEALIEQGARTNE 726
Query: 205 TDLQGW-------QEVHQAC------------------RNGL-----VQHVD--HLLF-Y 231
D G QE H C RN L H D LLF +
Sbjct: 727 IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSH 786
Query: 232 GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
GAD+N ++A G L++ A+ Q + A L G + EA + +T V+ G++++
Sbjct: 787 GADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMV 846
Query: 292 EVIKNYKSD 300
+V+ Y +D
Sbjct: 847 QVLIAYHAD 855
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/215 (26%), Positives = 95/215 (44%), Gaps = 8/215 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G D + G + N G T L IAA +I+ L++ GA +++ DG T
Sbjct: 506 GHEDIVLNLLQHGAEVN-KADNEGRTAL-IAAAYMGHREIVEHLLDHGAEVNHEDVDGRT 563
Query: 145 AMHRAV-----EKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
A+ A K V L++ GA ++ D G+TPL ++ ++ + LL
Sbjct: 564 ALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVV-DLLLEGG 622
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + TD G + A G V+ LLF+GA +++ ++ G T L + + R
Sbjct: 623 ADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVR 682
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL RG D+ + A TP +A G+ + E +
Sbjct: 683 TLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 717
Score = 65.7 bits (153), Expect = 4e-10
Identities = 53/202 (26%), Positives = 87/202 (43%), Gaps = 4/202 (1%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
C + AA I++ L+ GA ++ +G TA+ A E V+ LL+
Sbjct: 490 CADADSRTALRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLD 549
Query: 164 LGASPNYKDGKGLTPLYLSV----TNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRN 219
GA N++D G T L ++ +K + L+ A + D G + A
Sbjct: 550 HGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYE 609
Query: 220 GLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPY 279
G V VD LL GAD++ + +G TPL A S LLF G ++++ +T
Sbjct: 610 GHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVL 669
Query: 280 QVAVIAGNLDLAEVIKNYKSDE 301
+A GN+++ + + DE
Sbjct: 670 SIASAQGNVEVVRTLLDRGLDE 691
Score = 62.5 bits (145), Expect = 4e-09
Identities = 43/173 (24%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ + +D R DG A+ A + + V+ L GA N KD G LY+ + +
Sbjct: 750 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYI-LALEN 808
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ E L + A + A+D +G +H +C G ++ V L+ Y AD+NA + + L
Sbjct: 809 QLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQ 868
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + L+ G + T +A G++D+ +V+ + +D
Sbjct: 869 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGAD 921
Score = 61.3 bits (142), Expect = 8e-09
Identities = 42/173 (24%), Positives = 73/173 (42%), Gaps = 1/173 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L++ GA ++ +G T + A SL+ V L+ GA +D G TPL L+
Sbjct: 382 LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGH 441
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
++ L+ A I TD GW + A G + V LL+ G ++ +A T L
Sbjct: 442 TKVV-NCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALR 500
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + LL G + + +T A G+ ++ E + ++ ++
Sbjct: 501 AAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAE 553
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/195 (24%), Positives = 87/195 (44%), Gaps = 2/195 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G L +AA L+ I+ L + GA ++ + DG ++ +N L + LE GA+
Sbjct: 764 GRNALRVAA-LEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGAN 822
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
D +G T L++S ++ + L+ HA + A D + + A G V+ V
Sbjct: 823 VEASDAEGRTALHVSCWQGHMEMV-QVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQL 881
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
L+ +GA ++ G T L + A + LL G D + +T +VA G+
Sbjct: 882 LIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGH 941
Query: 288 LDLAEVIKNYKSDEI 302
+ ++++ Y + +
Sbjct: 942 SQIIKLLEKYGASSL 956
Score = 37.9 bits (84), Expect = 0.087
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 3/139 (2%)
Query: 156 EAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
E ++ L++ GA N +D + + + + D + TLL + A++ D G +
Sbjct: 346 EVLQLLVKAGAHVNSEDDR-TSCIVRQALEREDSI--RTLLDNGASVNQCDSNGRTLLAN 402
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A +G + V+ L+ GAD+ +A G+TPL + A L+ G + +
Sbjct: 403 AAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDG 462
Query: 276 QTPYQVAVIAGNLDLAEVI 294
T + A G+ ++ +
Sbjct: 463 WTALRSAAWGGHTEVVSAL 481
>BC024725-1|AAH24725.1| 743|Homo sapiens ANKRD50 protein protein.
Length = 743
Score = 80.2 bits (189), Expect = 2e-14
Identities = 58/202 (28%), Positives = 96/202 (47%), Gaps = 5/202 (2%)
Query: 103 HCQETGETPLTIAA----GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
H G T L++AA K A ++ L++ GA +D+ +DG T + A + ++ V
Sbjct: 19 HEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVV 78
Query: 159 KTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACR 218
LLE GA ++ D G TPL L+ + + TLL A + + D +G + A
Sbjct: 79 DLLLEGGADVDHTDNNGRTPL-LAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASA 137
Query: 219 NGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
G V+ V LL G D N R+ +G TPLH+ A L+ +G ++ + P
Sbjct: 138 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIP 197
Query: 279 YQVAVIAGNLDLAEVIKNYKSD 300
+ +A G+ D +++ KS+
Sbjct: 198 FILASQEGHYDCVQILLENKSN 219
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/249 (28%), Positives = 112/249 (44%), Gaps = 36/249 (14%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G +D + G D + H G TPL AA + A ++ L+ GA +D +G T
Sbjct: 73 GHVDVVDLLLEGGADVD-HTDNNGRTPLLAAASM-GHASVVNTLLFWGAAVDSIDSEGRT 130
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+ A + ++E V+TLL+ G N++D G TPL+++ + L+CE L+ A
Sbjct: 131 VLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAF-EGHRLICEALIEQGARTNE 189
Query: 205 TDLQGW-------QEVHQAC------------------RNGL-----VQHVD--HLLF-Y 231
D G QE H C RN L H D LLF +
Sbjct: 190 IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSH 249
Query: 232 GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
GAD+N ++A G L++ A+ Q + A L G + EA + +T V+ G++++
Sbjct: 250 GADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMV 309
Query: 292 EVIKNYKSD 300
+V+ Y +D
Sbjct: 310 QVLIAYHAD 318
Score = 63.7 bits (148), Expect = 2e-09
Identities = 48/177 (27%), Positives = 83/177 (46%), Gaps = 6/177 (3%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAV-----EKNSLEAVKTLLELGASPNYKDGKGLT 177
+I+ L++ GA +++ DG TA+ A K V L++ GA ++ D G+T
Sbjct: 5 EIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMT 64
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNA 237
PL ++ ++ + LL A + TD G + A G V+ LLF+GA +++
Sbjct: 65 PLLVAAYEGHVDVV-DLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDS 123
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
++ G T L + + R LL RG D+ + A TP +A G+ + E +
Sbjct: 124 IDSEGRTVLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 180
Score = 62.5 bits (145), Expect = 4e-09
Identities = 43/173 (24%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ + +D R DG A+ A + + V+ L GA N KD G LY+ + +
Sbjct: 213 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYI-LALEN 271
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ E L + A + A+D +G +H +C G ++ V L+ Y AD+NA + + L
Sbjct: 272 QLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQ 331
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + L+ G + T +A G++D+ +V+ + +D
Sbjct: 332 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGAD 384
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/195 (24%), Positives = 87/195 (44%), Gaps = 2/195 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G L +AA L+ I+ L + GA ++ + DG ++ +N L + LE GA+
Sbjct: 227 GRNALRVAA-LEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGAN 285
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
D +G T L++S ++ + L+ HA + A D + + A G V+ V
Sbjct: 286 VEASDAEGRTALHVSCWQGHMEMV-QVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQL 344
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
L+ +GA ++ G T L + A + LL G D + +T +VA G+
Sbjct: 345 LIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGH 404
Query: 288 LDLAEVIKNYKSDEI 302
+ ++++ Y + +
Sbjct: 405 SQIIKLLEKYGASSL 419
Score = 54.8 bits (126), Expect = 7e-07
Identities = 42/150 (28%), Positives = 68/150 (45%), Gaps = 4/150 (2%)
Query: 156 EAVKTLLELGASPNYKDGKGLTPLYLSV----TNKTDPLLCETLLHDHATIGATDLQGWQ 211
E V+ LL+ GA N++D G T L ++ +K + L+ A + D G
Sbjct: 5 EIVEHLLDHGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMT 64
Query: 212 EVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ A G V VD LL GAD++ + +G TPL A S LLF G +++
Sbjct: 65 PLLVAAYEGHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSI 124
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSDE 301
+ +T +A GN+++ + + DE
Sbjct: 125 DSEGRTVLSIASAQGNVEVVRTLLDRGLDE 154
>AK127496-1|BAC87007.1| 1375|Homo sapiens protein ( Homo sapiens
cDNA FLJ45589 fis, clone BRTHA3014547, weakly similar
to Ankyrin 1. ).
Length = 1375
Score = 80.2 bits (189), Expect = 2e-14
Identities = 58/202 (28%), Positives = 96/202 (47%), Gaps = 5/202 (2%)
Query: 103 HCQETGETPLTIAA----GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
H G T L++AA K A ++ L++ GA +D+ +DG T + A + ++ V
Sbjct: 651 HEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVV 710
Query: 159 KTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACR 218
LLE GA ++ D G TPL L+ + + TLL A + + D +G + A
Sbjct: 711 DLLLEGGADVDHTDNNGRTPL-LAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASA 769
Query: 219 NGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
G V+ V LL G D N R+ +G TPLH+ A L+ +G ++ + P
Sbjct: 770 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIP 829
Query: 279 YQVAVIAGNLDLAEVIKNYKSD 300
+ +A G+ D +++ KS+
Sbjct: 830 FILASQEGHYDCVQILLENKSN 851
Score = 77.0 bits (181), Expect = 2e-13
Identities = 60/228 (26%), Positives = 102/228 (44%), Gaps = 9/228 (3%)
Query: 73 ANLRRFLEHVTH-GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNG 131
+N R L + + G +D + ++G D G TPLT+AA + K++ L+
Sbjct: 489 SNGRTLLANAAYSGSLDVVNLLVSRGADLEIE-DAHGHTPLTLAAR-QGHTKVVNCLIGC 546
Query: 132 GALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLL 191
GA +++ +DG TA+ A E V LL G + D T L + + ++
Sbjct: 547 GANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALRAAAWGGREDIV 606
Query: 192 CETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAV 251
L H A + D +G + A G + V+HLL +GA++N + G T L V A+
Sbjct: 607 LNLLQHG-AEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAAL 665
Query: 252 -----NAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
S L+ RG + + + TP VA G++D+ +++
Sbjct: 666 CVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLL 713
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/249 (28%), Positives = 112/249 (44%), Gaps = 36/249 (14%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G +D + G D + H G TPL AA + A ++ L+ GA +D +G T
Sbjct: 705 GHVDVVDLLLEGGADVD-HTDNNGRTPLLAAASM-GHASVVNTLLFWGAAVDSIDSEGRT 762
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+ A + ++E V+TLL+ G N++D G TPL+++ + L+CE L+ A
Sbjct: 763 VLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAF-EGHRLICEALIEQGARTNE 821
Query: 205 TDLQGW-------QEVHQAC------------------RNGL-----VQHVD--HLLF-Y 231
D G QE H C RN L H D LLF +
Sbjct: 822 IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSH 881
Query: 232 GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
GAD+N ++A G L++ A+ Q + A L G + EA + +T V+ G++++
Sbjct: 882 GADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMV 941
Query: 292 EVIKNYKSD 300
+V+ Y +D
Sbjct: 942 QVLIAYHAD 950
Score = 68.9 bits (161), Expect = 4e-11
Identities = 58/215 (26%), Positives = 96/215 (44%), Gaps = 8/215 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G+ D + G + N G T L IAA +I+ L++ GA +++ DG T
Sbjct: 601 GREDIVLNLLQHGAEVN-KADNEGRTAL-IAAAYMGHREIVEHLLDHGAEVNHEDVDGRT 658
Query: 145 AMHRAV-----EKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
A+ A K V L++ GA ++ D G+TPL ++ ++ + LL
Sbjct: 659 ALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVV-DLLLEGG 717
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + TD G + A G V+ LLF+GA +++ ++ G T L + + R
Sbjct: 718 ADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVR 777
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL RG D+ + A TP +A G+ + E +
Sbjct: 778 TLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 812
Score = 65.7 bits (153), Expect = 4e-10
Identities = 53/202 (26%), Positives = 87/202 (43%), Gaps = 4/202 (1%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
C + AA I++ L+ GA ++ +G TA+ A E V+ LL+
Sbjct: 585 CADADSRTALRAAAWGGREDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLD 644
Query: 164 LGASPNYKDGKGLTPLYLSV----TNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRN 219
GA N++D G T L ++ +K + L+ A + D G + A
Sbjct: 645 HGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYE 704
Query: 220 GLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPY 279
G V VD LL GAD++ + +G TPL A S LLF G ++++ +T
Sbjct: 705 GHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVL 764
Query: 280 QVAVIAGNLDLAEVIKNYKSDE 301
+A GN+++ + + DE
Sbjct: 765 SIASAQGNVEVVRTLLDRGLDE 786
Score = 62.5 bits (145), Expect = 4e-09
Identities = 43/173 (24%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ + +D R DG A+ A + + V+ L GA N KD G LY+ + +
Sbjct: 845 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYI-LALEN 903
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ E L + A + A+D +G +H +C G ++ V L+ Y AD+NA + + L
Sbjct: 904 QLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQ 963
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + L+ G + T +A G++D+ +V+ + +D
Sbjct: 964 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGAD 1016
Score = 61.7 bits (143), Expect = 6e-09
Identities = 42/173 (24%), Positives = 74/173 (42%), Gaps = 1/173 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L++ GA ++ +G T + A SL+ V L+ GA +D G TPL L+
Sbjct: 477 LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGH 536
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
++ L+ A I TD GW + A G + V LL+ G ++ +A T L
Sbjct: 537 TKVV-NCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTALR 595
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A ++ LL G + + +T A G+ ++ E + ++ ++
Sbjct: 596 AAAWGGREDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAE 648
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/195 (24%), Positives = 87/195 (44%), Gaps = 2/195 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G L +AA L+ I+ L + GA ++ + DG ++ +N L + LE GA+
Sbjct: 859 GRNALRVAA-LEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGAN 917
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
D +G T L++S ++ + L+ HA + A D + + A G V+ V
Sbjct: 918 VEASDAEGRTALHVSCWQGHMEMV-QVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQL 976
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
L+ +GA ++ G T L + A + LL G D + +T +VA G+
Sbjct: 977 LIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGH 1036
Query: 288 LDLAEVIKNYKSDEI 302
+ ++++ Y + +
Sbjct: 1037 SQIIKLLEKYGASSL 1051
Score = 37.9 bits (84), Expect = 0.087
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 3/139 (2%)
Query: 156 EAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
E ++ L++ GA N +D + + + + D + TLL + A++ D G +
Sbjct: 441 EVLQLLVKAGAHVNSEDDR-TSCIVRQALEREDSI--RTLLDNGASVNQCDSNGRTLLAN 497
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A +G + V+ L+ GAD+ +A G+TPL + A L+ G + +
Sbjct: 498 AAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDG 557
Query: 276 QTPYQVAVIAGNLDLAEVI 294
T + A G+ ++ +
Sbjct: 558 WTALRSAAWGGHTEVVSAL 576
>AB033049-1|BAA86537.2| 1089|Homo sapiens KIAA1223 protein protein.
Length = 1089
Score = 80.2 bits (189), Expect = 2e-14
Identities = 58/202 (28%), Positives = 96/202 (47%), Gaps = 5/202 (2%)
Query: 103 HCQETGETPLTIAA----GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
H G T L++AA K A ++ L++ GA +D+ +DG T + A + ++ V
Sbjct: 365 HEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVV 424
Query: 159 KTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACR 218
LLE GA ++ D G TPL L+ + + TLL A + + D +G + A
Sbjct: 425 DLLLEGGADVDHTDNNGRTPL-LAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASA 483
Query: 219 NGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
G V+ V LL G D N R+ +G TPLH+ A L+ +G ++ + P
Sbjct: 484 QGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEALIEQGARTNEIDNDGRIP 543
Query: 279 YQVAVIAGNLDLAEVIKNYKSD 300
+ +A G+ D +++ KS+
Sbjct: 544 FILASQEGHYDCVQILLENKSN 565
Score = 76.6 bits (180), Expect = 2e-13
Identities = 70/249 (28%), Positives = 112/249 (44%), Gaps = 36/249 (14%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G +D + G D + H G TPL AA + A ++ L+ GA +D +G T
Sbjct: 419 GHVDVVDLLLEGGADVD-HTDNNGRTPLLAAASM-GHASVVNTLLFWGAAVDSIDSEGRT 476
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
+ A + ++E V+TLL+ G N++D G TPL+++ + L+CE L+ A
Sbjct: 477 VLSIASAQGNVEVVRTLLDRGLDENHRDDAGWTPLHMAAF-EGHRLICEALIEQGARTNE 535
Query: 205 TDLQGW-------QEVHQAC------------------RNGL-----VQHVD--HLLF-Y 231
D G QE H C RN L H D LLF +
Sbjct: 536 IDNDGRIPFILASQEGHYDCVQILLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSH 595
Query: 232 GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
GAD+N ++A G L++ A+ Q + A L G + EA + +T V+ G++++
Sbjct: 596 GADVNCKDADGRPTLYILALENQLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMV 655
Query: 292 EVIKNYKSD 300
+V+ Y +D
Sbjct: 656 QVLIAYHAD 664
Score = 76.2 bits (179), Expect = 3e-13
Identities = 60/228 (26%), Positives = 102/228 (44%), Gaps = 9/228 (3%)
Query: 73 ANLRRFLEHVTH-GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNG 131
+N R L + + G +D + ++G D G TPLT+AA + K++ L+
Sbjct: 203 SNGRTLLANAAYSGSLDVVNLLVSRGADLEIE-DAHGHTPLTLAAR-QGHTKVVNCLIGC 260
Query: 132 GALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLL 191
GA +++ +DG TA+ A E V LL G + D T L + + ++
Sbjct: 261 GANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLRAAAWGGHEDIV 320
Query: 192 CETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAV 251
L H A + D +G + A G + V+HLL +GA++N + G T L V A+
Sbjct: 321 LNLLQHG-AEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAEVNHEDVDGRTALSVAAL 379
Query: 252 -----NAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
S L+ RG + + + TP VA G++D+ +++
Sbjct: 380 CVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVVDLL 427
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/215 (26%), Positives = 95/215 (44%), Gaps = 8/215 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G D + G + N G T L IAA +I+ L++ GA +++ DG T
Sbjct: 315 GHEDIVLNLLQHGAEVN-KADNEGRTAL-IAAAYMGHREIVEHLLDHGAEVNHEDVDGRT 372
Query: 145 AMHRAV-----EKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
A+ A K V L++ GA ++ D G+TPL ++ ++ + LL
Sbjct: 373 ALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYEGHVDVV-DLLLEGG 431
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + TD G + A G V+ LLF+GA +++ ++ G T L + + R
Sbjct: 432 ADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVLSIASAQGNVEVVR 491
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL RG D+ + A TP +A G+ + E +
Sbjct: 492 TLLDRGLDENHRDDAGWTPLHMAAFEGHRLICEAL 526
Score = 66.5 bits (155), Expect = 2e-10
Identities = 53/202 (26%), Positives = 88/202 (43%), Gaps = 4/202 (1%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
C + + AA I++ L+ GA ++ +G TA+ A E V+ LL+
Sbjct: 299 CADADSRTVLRAAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLD 358
Query: 164 LGASPNYKDGKGLTPLYLSV----TNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRN 219
GA N++D G T L ++ +K + L+ A + D G + A
Sbjct: 359 HGAEVNHEDVDGRTALSVAALCVPASKGHASVVSLLIDRGAEVDHCDKDGMTPLLVAAYE 418
Query: 220 GLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPY 279
G V VD LL GAD++ + +G TPL A S LLF G ++++ +T
Sbjct: 419 GHVDVVDLLLEGGADVDHTDNNGRTPLLAAASMGHASVVNTLLFWGAAVDSIDSEGRTVL 478
Query: 280 QVAVIAGNLDLAEVIKNYKSDE 301
+A GN+++ + + DE
Sbjct: 479 SIASAQGNVEVVRTLLDRGLDE 500
Score = 62.5 bits (145), Expect = 4e-09
Identities = 43/173 (24%), Positives = 77/173 (44%), Gaps = 1/173 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ + +D R DG A+ A + + V+ L GA N KD G LY+ + +
Sbjct: 559 LLENKSNIDQRGYDGRNALRVAALEGHRDIVELLFSHGADVNCKDADGRPTLYI-LALEN 617
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ E L + A + A+D +G +H +C G ++ V L+ Y AD+NA + + L
Sbjct: 618 QLTMAEYFLENGANVEASDAEGRTALHVSCWQGHMEMVQVLIAYHADVNAADNEKRSALQ 677
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + L+ G + T +A G++D+ +V+ + +D
Sbjct: 678 SAAWQGHVKVVQLLIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGAD 730
Score = 60.9 bits (141), Expect = 1e-08
Identities = 42/173 (24%), Positives = 73/173 (42%), Gaps = 1/173 (0%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L++ GA ++ +G T + A SL+ V L+ GA +D G TPL L+
Sbjct: 191 LLDNGASVNQCDSNGRTLLANAAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGH 250
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
++ L+ A I TD GW + A G + V LL+ G ++ +A T L
Sbjct: 251 TKVV-NCLIGCGANINHTDQDGWTALRSAAWGGHTEVVSALLYAGVKVDCADADSRTVLR 309
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + LL G + + +T A G+ ++ E + ++ ++
Sbjct: 310 AAAWGGHEDIVLNLLQHGAEVNKADNEGRTALIAAAYMGHREIVEHLLDHGAE 362
Score = 57.2 bits (132), Expect = 1e-07
Identities = 47/195 (24%), Positives = 87/195 (44%), Gaps = 2/195 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G L +AA L+ I+ L + GA ++ + DG ++ +N L + LE GA+
Sbjct: 573 GRNALRVAA-LEGHRDIVELLFSHGADVNCKDADGRPTLYILALENQLTMAEYFLENGAN 631
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
D +G T L++S ++ + L+ HA + A D + + A G V+ V
Sbjct: 632 VEASDAEGRTALHVSCWQGHMEMV-QVLIAYHADVNAADNEKRSALQSAAWQGHVKVVQL 690
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
L+ +GA ++ G T L + A + LL G D + +T +VA G+
Sbjct: 691 LIEHGAVVDHTCNQGATALCIAAQEGHIDVVQVLLEHGADPNHADQFGRTAMRVAAKNGH 750
Query: 288 LDLAEVIKNYKSDEI 302
+ ++++ Y + +
Sbjct: 751 SQIIKLLEKYGASSL 765
Score = 37.9 bits (84), Expect = 0.087
Identities = 31/139 (22%), Positives = 61/139 (43%), Gaps = 3/139 (2%)
Query: 156 EAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
E ++ L++ GA N +D + + + + D + TLL + A++ D G +
Sbjct: 155 EVLQLLVKAGAHVNSEDDR-TSCIVRQALEREDSI--RTLLDNGASVNQCDSNGRTLLAN 211
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A +G + V+ L+ GAD+ +A G+TPL + A L+ G + +
Sbjct: 212 AAYSGSLDVVNLLVSRGADLEIEDAHGHTPLTLAARQGHTKVVNCLIGCGANINHTDQDG 271
Query: 276 QTPYQVAVIAGNLDLAEVI 294
T + A G+ ++ +
Sbjct: 272 WTALRSAAWGGHTEVVSAL 290
>Z26634-1|CAB42644.1| 3925|Homo sapiens ankyrin B (440 kDa) protein.
Length = 3925
Score = 79.8 bits (188), Expect = 2e-14
Identities = 62/201 (30%), Positives = 94/201 (46%), Gaps = 5/201 (2%)
Query: 96 KGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSL 155
KG P+ + G TPL IAA K+ +I L+N GA + T+ G T +H A ++
Sbjct: 618 KGASPHATAKN-GYTPLHIAAK-KNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHT 675
Query: 156 EAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVH 214
+ V LL+ GA+ + GLT L+L+ + D + +L H A A G+ +
Sbjct: 676 DMVTLLLDKGANIHMSTKSGLTSLHLAA--QEDKVNVADILTKHGADQDAHTKLGYTPLI 733
Query: 215 QACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFA 274
AC G V+ V+ LL GA++NA+ +G TPLH A LL G A
Sbjct: 734 VACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTAN 793
Query: 275 NQTPYQVAVIAGNLDLAEVIK 295
T +A G + + + +K
Sbjct: 794 GNTALAIAKRLGYISVVDTLK 814
Score = 79.4 bits (187), Expect = 3e-14
Identities = 67/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
H H ++ K+ K +PN G TPL IA K+ K++ LV GA + T
Sbjct: 374 HCGHYRVTKLL--LDKRANPNARALN-GFTPLHIACK-KNRIKVMELLVKYGASIQAITE 429
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLLHDH 199
G T +H A L V LL+ GASP+ + +G T L+++ + + + C LL +
Sbjct: 430 SGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRC--LLRNG 487
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + A + +H A R G + V LL + A +A +G TPLH+ A Q A
Sbjct: 488 ALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVAS 547
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL G TP VA G+LD+A+++
Sbjct: 548 VLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLL 582
Score = 78.6 bits (185), Expect = 5e-14
Identities = 57/192 (29%), Positives = 90/192 (46%), Gaps = 2/192 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TPL IAA + + L+N GA +D+ R+G T +H A ++ + VK LL+ G
Sbjct: 231 ESGFTPLHIAAHYGN-VNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG 289
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ K GLTPL+ + + D ++ E LL A + A G +H A + V+ V
Sbjct: 290 GQIDAKTRDGLTPLHCAARSGHDQVV-ELLLERGAPLLARTKNGLSPLHMAAQGDHVECV 348
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
HLL + A ++ T LHV A + LL + + A TP +A
Sbjct: 349 KHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKK 408
Query: 286 GNLDLAEVIKNY 297
+ + E++ Y
Sbjct: 409 NRIKVMELLVKY 420
Score = 76.2 bits (179), Expect = 3e-13
Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL I+A + + L+ GA T+ G T +H A + SL+ K LL+ A+
Sbjct: 530 GYTPLHISAR-EGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAA 588
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ GLTPL+++ + + + LL A+ AT G+ +H A + +Q
Sbjct: 589 ADSAGKNGLTPLHVAA-HYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIAST 647
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL YGA+ N G TPLH+ + LL +G + + T +A
Sbjct: 648 LLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDK 707
Query: 288 LDLAEVIKNYKSDE 301
+++A+++ + +D+
Sbjct: 708 VNVADILTKHGADQ 721
Score = 71.7 bits (168), Expect = 6e-12
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL AA + + L G LL RT++G + +H A + + +E VK LL+ A
Sbjct: 299 GLTPLHCAARSGHDQVVELLLERGAPLLA-RTKNGLSPLHMAAQGDHVECVKHLLQHKAP 357
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ LT L+++ + + + LL A A L G+ +H AC+ ++ ++
Sbjct: 358 VDDVTLDYLTALHVAA-HCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMEL 416
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
L+ YGA + A SG TP+HV A + LL G + N +T +A AG
Sbjct: 417 LVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQ 476
Query: 288 LDLAEVI 294
+++ +
Sbjct: 477 VEVVRCL 483
Score = 71.7 bits (168), Expect = 6e-12
Identities = 58/187 (31%), Positives = 84/187 (44%), Gaps = 4/187 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TP+ +AA + I++ L+ GA D G TA+H A +E V+ LL G
Sbjct: 429 ESGLTPIHVAAFM-GHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 487
Query: 166 ASPNYKDGKGLTPLYL-SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
A + + + TPL++ S KT+ + + LL A A G+ +H + R G V
Sbjct: 488 ALVDARAREEQTPLHIASRLGKTE--IVQLLLQHMAHPDAATTNGYTPLHISAREGQVDV 545
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
LL GA + G TPLHV A A+ LL R ++ TP VA
Sbjct: 546 ASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAH 605
Query: 285 AGNLDLA 291
N +A
Sbjct: 606 YDNQKVA 612
Score = 63.3 bits (147), Expect = 2e-09
Identities = 43/172 (25%), Positives = 80/172 (46%), Gaps = 1/172 (0%)
Query: 129 VNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTD 188
V +++ T G T +H A ++ LL GA+ ++ G+TPL+++ + + +
Sbjct: 220 VQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVA-SKRGN 278
Query: 189 PLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHV 248
+ + LL I A G +H A R+G Q V+ LL GA + AR +G +PLH+
Sbjct: 279 TNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHM 338
Query: 249 CAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A C + LL + + T VA G+ + +++ + +++
Sbjct: 339 AAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRAN 390
Score = 62.1 bits (144), Expect = 5e-09
Identities = 61/228 (26%), Positives = 101/228 (44%), Gaps = 17/228 (7%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL G +DK+ + G+D N C + G L +AA + ++ L+ G+ +D
Sbjct: 35 FLRAARAGNLDKVVEYLKGGIDINT-CNQNGLNALHLAAK-EGHVGLVQELLGRGSSVDS 92
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLL 196
T+ G+TA+H A E VK L++ GA+ N + G TPLY++ N D + + LL
Sbjct: 93 ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHID--VVKYLL 150
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDS 256
+ A G+ + A + G Q V LL + + + LH+ A
Sbjct: 151 ENGANQSTATEDGFTPLAVALQQGHNQAVAILL----ENDTKGKVRLPALHIAARKDDTK 206
Query: 257 CARQLL--FRGCDKEALNFANQ------TPYQVAVIAGNLDLAEVIKN 296
A LL D ++ N+ TP +A GN+++A ++ N
Sbjct: 207 SAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLN 254
Score = 62.1 bits (144), Expect = 5e-09
Identities = 53/192 (27%), Positives = 92/192 (47%), Gaps = 8/192 (4%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IA+ L A+++ LV GA ++ ++++G T ++ A ++N ++ VK LLE GA+
Sbjct: 97 GNTALHIAS-LAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155
Query: 168 PNYKDGKGLTPLYLSVT---NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
+ G TPL +++ N+ +L E + A + ++ ++ L+
Sbjct: 156 QSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSA--ALLLQ 213
Query: 225 VDHLLFYGADM--NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
DH + M N SG TPLH+ A + A LL RG + TP VA
Sbjct: 214 NDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVA 273
Query: 283 VIAGNLDLAEVI 294
GN ++ +++
Sbjct: 274 SKRGNTNMVKLL 285
>X56958-1|CAA40279.2| 1872|Homo sapiens ankyrin (brank-2) protein.
Length = 1872
Score = 79.8 bits (188), Expect = 2e-14
Identities = 62/201 (30%), Positives = 94/201 (46%), Gaps = 5/201 (2%)
Query: 96 KGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSL 155
KG P+ + G TPL IAA K+ +I L+N GA + T+ G T +H A ++
Sbjct: 618 KGASPHATAKN-GYTPLHIAAK-KNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHT 675
Query: 156 EAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVH 214
+ V LL+ GA+ + GLT L+L+ + D + +L H A A G+ +
Sbjct: 676 DMVTLLLDKGANIHMSTKSGLTSLHLAA--QEDKVNVADILTKHGADQDAHTKLGYTPLI 733
Query: 215 QACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFA 274
AC G V+ V+ LL GA++NA+ +G TPLH A LL G A
Sbjct: 734 VACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTAN 793
Query: 275 NQTPYQVAVIAGNLDLAEVIK 295
T +A G + + + +K
Sbjct: 794 GNTALAIAKRLGYISVVDTLK 814
Score = 79.4 bits (187), Expect = 3e-14
Identities = 67/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
H H ++ K+ K +PN G TPL IA K+ K++ LV GA + T
Sbjct: 374 HCGHYRVTKLL--LDKRANPNARALN-GFTPLHIACK-KNRIKVMELLVKYGASIQAITE 429
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLLHDH 199
G T +H A L V LL+ GASP+ + +G T L+++ + + + C LL +
Sbjct: 430 SGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRC--LLRNG 487
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + A + +H A R G + V LL + A +A +G TPLH+ A Q A
Sbjct: 488 ALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVAS 547
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL G TP VA G+LD+A+++
Sbjct: 548 VLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLL 582
Score = 78.6 bits (185), Expect = 5e-14
Identities = 57/192 (29%), Positives = 90/192 (46%), Gaps = 2/192 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TPL IAA + + L+N GA +D+ R+G T +H A ++ + VK LL+ G
Sbjct: 231 ESGFTPLHIAAHYGN-VNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG 289
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ K GLTPL+ + + D ++ E LL A + A G +H A + V+ V
Sbjct: 290 GQIDAKTRDGLTPLHCAARSGHDQVV-ELLLERGAPLLARTKNGLSPLHMAAQGDHVECV 348
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
HLL + A ++ T LHV A + LL + + A TP +A
Sbjct: 349 KHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKK 408
Query: 286 GNLDLAEVIKNY 297
+ + E++ Y
Sbjct: 409 NRIKVMELLVKY 420
Score = 76.2 bits (179), Expect = 3e-13
Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL I+A + + L+ GA T+ G T +H A + SL+ K LL+ A+
Sbjct: 530 GYTPLHISAR-EGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAA 588
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ GLTPL+++ + + + LL A+ AT G+ +H A + +Q
Sbjct: 589 ADSAGKNGLTPLHVAA-HYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIAST 647
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL YGA+ N G TPLH+ + LL +G + + T +A
Sbjct: 648 LLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDK 707
Query: 288 LDLAEVIKNYKSDE 301
+++A+++ + +D+
Sbjct: 708 VNVADILTKHGADQ 721
Score = 71.7 bits (168), Expect = 6e-12
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL AA + + L G LL RT++G + +H A + + +E VK LL+ A
Sbjct: 299 GLTPLHCAARSGHDQVVELLLERGAPLLA-RTKNGLSPLHMAAQGDHVECVKHLLQHKAP 357
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ LT L+++ + + + LL A A L G+ +H AC+ ++ ++
Sbjct: 358 VDDVTLDYLTALHVAA-HCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMEL 416
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
L+ YGA + A SG TP+HV A + LL G + N +T +A AG
Sbjct: 417 LVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQ 476
Query: 288 LDLAEVI 294
+++ +
Sbjct: 477 VEVVRCL 483
Score = 71.7 bits (168), Expect = 6e-12
Identities = 58/187 (31%), Positives = 84/187 (44%), Gaps = 4/187 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TP+ +AA + I++ L+ GA D G TA+H A +E V+ LL G
Sbjct: 429 ESGLTPIHVAAFM-GHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 487
Query: 166 ASPNYKDGKGLTPLYL-SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
A + + + TPL++ S KT+ + + LL A A G+ +H + R G V
Sbjct: 488 ALVDARAREEQTPLHIASRLGKTE--IVQLLLQHMAHPDAATTNGYTPLHISAREGQVDV 545
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
LL GA + G TPLHV A A+ LL R ++ TP VA
Sbjct: 546 ASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAH 605
Query: 285 AGNLDLA 291
N +A
Sbjct: 606 YDNQKVA 612
Score = 63.3 bits (147), Expect = 2e-09
Identities = 43/172 (25%), Positives = 80/172 (46%), Gaps = 1/172 (0%)
Query: 129 VNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTD 188
V +++ T G T +H A ++ LL GA+ ++ G+TPL+++ + + +
Sbjct: 220 VQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVA-SKRGN 278
Query: 189 PLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHV 248
+ + LL I A G +H A R+G Q V+ LL GA + AR +G +PLH+
Sbjct: 279 TNMVKLLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHM 338
Query: 249 CAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A C + LL + + T VA G+ + +++ + +++
Sbjct: 339 AAQGDHVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRAN 390
Score = 62.1 bits (144), Expect = 5e-09
Identities = 61/228 (26%), Positives = 101/228 (44%), Gaps = 17/228 (7%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL G +DK+ + G+D N C + G L +AA + ++ L+ G+ +D
Sbjct: 35 FLRAARAGNLDKVVEYLKGGIDINT-CNQNGLNALHLAAK-EGHVGLVQELLGRGSSVDS 92
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLL 196
T+ G+TA+H A E VK L++ GA+ N + G TPLY++ N D + + LL
Sbjct: 93 ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHID--VVKYLL 150
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDS 256
+ A G+ + A + G Q V LL + + + LH+ A
Sbjct: 151 ENGANQSTATEDGFTPLAVALQQGHNQAVAILL----ENDTKGKVRLPALHIAARKDDTK 206
Query: 257 CARQLL--FRGCDKEALNFANQ------TPYQVAVIAGNLDLAEVIKN 296
A LL D ++ N+ TP +A GN+++A ++ N
Sbjct: 207 SAALLLQNDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLN 254
Score = 62.1 bits (144), Expect = 5e-09
Identities = 53/192 (27%), Positives = 92/192 (47%), Gaps = 8/192 (4%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IA+ L A+++ LV GA ++ ++++G T ++ A ++N ++ VK LLE GA+
Sbjct: 97 GNTALHIAS-LAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 155
Query: 168 PNYKDGKGLTPLYLSVT---NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
+ G TPL +++ N+ +L E + A + ++ ++ L+
Sbjct: 156 QSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSA--ALLLQ 213
Query: 225 VDHLLFYGADM--NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
DH + M N SG TPLH+ A + A LL RG + TP VA
Sbjct: 214 NDHNADVQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVA 273
Query: 283 VIAGNLDLAEVI 294
GN ++ +++
Sbjct: 274 SKRGNTNMVKLL 285
>BX537758-1|CAD97827.1| 1863|Homo sapiens hypothetical protein
protein.
Length = 1863
Score = 79.8 bits (188), Expect = 2e-14
Identities = 62/201 (30%), Positives = 94/201 (46%), Gaps = 5/201 (2%)
Query: 96 KGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSL 155
KG P+ + G TPL IAA K+ +I L+N GA + T+ G T +H A ++
Sbjct: 597 KGASPHATAKN-GYTPLHIAAK-KNQMQIASTLLNYGAETNIVTKQGVTPLHLASQEGHT 654
Query: 156 EAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVH 214
+ V LL+ GA+ + GLT L+L+ + D + +L H A A G+ +
Sbjct: 655 DMVTLLLDKGANIHMSTKSGLTSLHLAA--QEDKVNVADILTKHGADQDAHTKLGYTPLI 712
Query: 215 QACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFA 274
AC G V+ V+ LL GA++NA+ +G TPLH A LL G A
Sbjct: 713 VACHYGNVKMVNFLLKQGANVNAKTKNGYTPLHQAAQQGHTHIINVLLQHGAKPNATTAN 772
Query: 275 NQTPYQVAVIAGNLDLAEVIK 295
T +A G + + + +K
Sbjct: 773 GNTALAIAKRLGYISVVDTLK 793
Score = 79.4 bits (187), Expect = 3e-14
Identities = 67/215 (31%), Positives = 100/215 (46%), Gaps = 7/215 (3%)
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
H H ++ K+ K +PN G TPL IA K+ K++ LV GA + T
Sbjct: 353 HCGHYRVTKLL--LDKRANPNARALN-GFTPLHIACK-KNRIKVMELLVKYGASIQAITE 408
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLLHDH 199
G T +H A L V LL+ GASP+ + +G T L+++ + + + C LL +
Sbjct: 409 SGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRC--LLRNG 466
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + A + +H A R G + V LL + A +A +G TPLH+ A Q A
Sbjct: 467 ALVDARAREEQTPLHIASRLGKTEIVQLLLQHMAHPDAATTNGYTPLHISAREGQVDVAS 526
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL G TP VA G+LD+A+++
Sbjct: 527 VLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLL 561
Score = 78.6 bits (185), Expect = 5e-14
Identities = 57/192 (29%), Positives = 90/192 (46%), Gaps = 2/192 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TPL IAA + + L+N GA +D+ R+G T +H A ++ + VK LL+ G
Sbjct: 210 ESGFTPLHIAAHYGN-VNVATLLLNRGAAVDFTARNGITPLHVASKRGNTNMVKLLLDRG 268
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ K GLTPL+ + + D ++ E LL A + A G +H A + V+ V
Sbjct: 269 GQIDAKTRDGLTPLHCAARSGHDQVV-ELLLERGAPLLARTKNGLSPLHMAAQGDHVECV 327
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
HLL + A ++ T LHV A + LL + + A TP +A
Sbjct: 328 KHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRANPNARALNGFTPLHIACKK 387
Query: 286 GNLDLAEVIKNY 297
+ + E++ Y
Sbjct: 388 NRIKVMELLVKY 399
Score = 76.2 bits (179), Expect = 3e-13
Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL I+A + + L+ GA T+ G T +H A + SL+ K LL+ A+
Sbjct: 509 GYTPLHISAR-EGQVDVASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAA 567
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ GLTPL+++ + + + LL A+ AT G+ +H A + +Q
Sbjct: 568 ADSAGKNGLTPLHVAA-HYDNQKVALLLLEKGASPHATAKNGYTPLHIAAKKNQMQIAST 626
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
LL YGA+ N G TPLH+ + LL +G + + T +A
Sbjct: 627 LLNYGAETNIVTKQGVTPLHLASQEGHTDMVTLLLDKGANIHMSTKSGLTSLHLAAQEDK 686
Query: 288 LDLAEVIKNYKSDE 301
+++A+++ + +D+
Sbjct: 687 VNVADILTKHGADQ 700
Score = 71.7 bits (168), Expect = 6e-12
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 2/187 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL AA + + L G LL RT++G + +H A + + +E VK LL+ A
Sbjct: 278 GLTPLHCAARSGHDQVVELLLERGAPLLA-RTKNGLSPLHMAAQGDHVECVKHLLQHKAP 336
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ LT L+++ + + + LL A A L G+ +H AC+ ++ ++
Sbjct: 337 VDDVTLDYLTALHVAA-HCGHYRVTKLLLDKRANPNARALNGFTPLHIACKKNRIKVMEL 395
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
L+ YGA + A SG TP+HV A + LL G + N +T +A AG
Sbjct: 396 LVKYGASIQAITESGLTPIHVAAFMGHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQ 455
Query: 288 LDLAEVI 294
+++ +
Sbjct: 456 VEVVRCL 462
Score = 71.7 bits (168), Expect = 6e-12
Identities = 58/187 (31%), Positives = 84/187 (44%), Gaps = 4/187 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E+G TP+ +AA + I++ L+ GA D G TA+H A +E V+ LL G
Sbjct: 408 ESGLTPIHVAAFM-GHLNIVLLLLQNGASPDVTNIRGETALHMAARAGQVEVVRCLLRNG 466
Query: 166 ASPNYKDGKGLTPLYL-SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
A + + + TPL++ S KT+ + + LL A A G+ +H + R G V
Sbjct: 467 ALVDARAREEQTPLHIASRLGKTE--IVQLLLQHMAHPDAATTNGYTPLHISAREGQVDV 524
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
LL GA + G TPLHV A A+ LL R ++ TP VA
Sbjct: 525 ASVLLEAGAAHSLATKKGFTPLHVAAKYGSLDVAKLLLQRRAAADSAGKNGLTPLHVAAH 584
Query: 285 AGNLDLA 291
N +A
Sbjct: 585 YDNQKVA 591
Score = 62.9 bits (146), Expect = 3e-09
Identities = 42/167 (25%), Positives = 79/167 (47%), Gaps = 1/167 (0%)
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
+++ T G T +H A ++ LL GA+ ++ G+TPL+++ + + + + +
Sbjct: 204 MVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVA-SKRGNTNMVK 262
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
LL I A G +H A R+G Q V+ LL GA + AR +G +PLH+ A
Sbjct: 263 LLLDRGGQIDAKTRDGLTPLHCAARSGHDQVVELLLERGAPLLARTKNGLSPLHMAAQGD 322
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
C + LL + + T VA G+ + +++ + +++
Sbjct: 323 HVECVKHLLQHKAPVDDVTLDYLTALHVAAHCGHYRVTKLLLDKRAN 369
Score = 62.1 bits (144), Expect = 5e-09
Identities = 53/192 (27%), Positives = 92/192 (47%), Gaps = 8/192 (4%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L IA+ L A+++ LV GA ++ ++++G T ++ A ++N ++ VK LLE GA+
Sbjct: 76 GNTALHIAS-LAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHIDVVKYLLENGAN 134
Query: 168 PNYKDGKGLTPLYLSVT---NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
+ G TPL +++ N+ +L E + A + ++ ++ L+
Sbjct: 135 QSTATEDGFTPLAVALQQGHNQAVAILLENDTKGKVRLPALHIAARKDDTKSA--ALLLQ 192
Query: 225 VDHLLFYGADM--NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
DH + M N SG TPLH+ A + A LL RG + TP VA
Sbjct: 193 NDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLNRGAAVDFTARNGITPLHVA 252
Query: 283 VIAGNLDLAEVI 294
GN ++ +++
Sbjct: 253 SKRGNTNMVKLL 264
Score = 61.7 bits (143), Expect = 6e-09
Identities = 61/228 (26%), Positives = 101/228 (44%), Gaps = 17/228 (7%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL G +DK+ + G+D N C + G L +AA + ++ L+ G+ +D
Sbjct: 14 FLRAARAGNLDKVVEYLKGGIDINT-CNQNGLNALHLAAK-EGHVGLVQELLGRGSSVDS 71
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLL 196
T+ G+TA+H A E VK L++ GA+ N + G TPLY++ N D + + LL
Sbjct: 72 ATKKGNTALHIASLAGQAEVVKVLVKEGANINAQSQNGFTPLYMAAQENHID--VVKYLL 129
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDS 256
+ A G+ + A + G Q V LL + + + LH+ A
Sbjct: 130 ENGANQSTATEDGFTPLAVALQQGHNQAVAILL----ENDTKGKVRLPALHIAARKDDTK 185
Query: 257 CARQLL--FRGCDKEALNFANQ------TPYQVAVIAGNLDLAEVIKN 296
A LL D ++ N+ TP +A GN+++A ++ N
Sbjct: 186 SAALLLQNDHNADIQSKMMVNRTTESGFTPLHIAAHYGNVNVATLLLN 233
>U95299-1|AAC32288.1| 2003|Homo sapiens Notch4 protein.
Length = 2003
Score = 79.4 bits (187), Expect = 3e-14
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Query: 128 LVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNK 186
L++GGA T G T +H A + A + LLE GA+PN D G TPL+ +V
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 187 TDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
+C+ LL T + A G + A R + V+ L+ AD+ AR+ G T
Sbjct: 1679 ARE-VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTA 1737
Query: 246 LHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LH A AR LL G DK+A + QTP +A G +++A+++
Sbjct: 1738 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLL 1786
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/200 (30%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G P H TGETPL +AA P L+ GA + R G T +H AV ++ E
Sbjct: 1623 GACPQAHTVGTGETPLHLAARFSRPTAAR-RLLEAGANPNQPDRAGRTPLHAAVAADARE 1681
Query: 157 AVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+ LL + + + G TPL L+ + L+ E L+ A +GA D G +H
Sbjct: 1682 VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLV-EELIAAQADVGARDKWGKTALHW 1740
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A + LL GAD +A++ TPL + A A+ LL G +E + A
Sbjct: 1741 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 1800
Query: 276 QTPYQVAVIAGNLDLAEVIK 295
P VA + DL +++
Sbjct: 1801 LAPADVAHQRNHWDLLTLLE 1820
>U89335-1|AAC63097.1| 1999|Homo sapiens notch4 protein.
Length = 1999
Score = 79.4 bits (187), Expect = 3e-14
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Query: 128 LVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNK 186
L++GGA T G T +H A + A + LLE GA+PN D G TPL+ +V
Sbjct: 1615 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1674
Query: 187 TDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
+C+ LL T + A G + A R + V+ L+ AD+ AR+ G T
Sbjct: 1675 ARE-VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTA 1733
Query: 246 LHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LH A AR LL G DK+A + QTP +A G +++A+++
Sbjct: 1734 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLL 1782
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/200 (30%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G P H TGETPL +AA P L+ GA + R G T +H AV ++ E
Sbjct: 1619 GACPQAHTVGTGETPLHLAARFSRPTAAR-RLLEAGANPNQPDRAGRTPLHAAVAADARE 1677
Query: 157 AVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+ LL + + + G TPL L+ + L+ E L+ A +GA D G +H
Sbjct: 1678 VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLV-EELIAAQADVGARDKWGKTALHW 1736
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A + LL GAD +A++ TPL + A A+ LL G +E + A
Sbjct: 1737 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 1796
Query: 276 QTPYQVAVIAGNLDLAEVIK 295
P VA + DL +++
Sbjct: 1797 LAPADVAHQRNHWDLLTLLE 1816
>D63395-1|BAA09708.1| 1095|Homo sapiens notch related protein
protein.
Length = 1095
Score = 79.4 bits (187), Expect = 3e-14
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Query: 128 LVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNK 186
L++GGA T G T +H A + A + LLE GA+PN D G TPL+ +V
Sbjct: 711 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 770
Query: 187 TDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
+C+ LL T + A G + A R + V+ L+ AD+ AR+ G T
Sbjct: 771 ARE-VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTA 829
Query: 246 LHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LH A AR LL G DK+A + QTP +A G +++A+++
Sbjct: 830 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLL 878
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/200 (30%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G P H TGETPL +AA P L+ GA + R G T +H AV ++ E
Sbjct: 715 GACPQAHTVGTGETPLHLAARFSRPTAAR-RLLEAGANPNQPDRAGRTPLHAAVAADARE 773
Query: 157 AVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+ LL + + + G TPL L+ + L+ E L+ A +GA D G +H
Sbjct: 774 VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLV-EELIAAQADVGARDKWGKTALHW 832
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A + LL GAD +A++ TPL + A A+ LL G +E + A
Sbjct: 833 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 892
Query: 276 QTPYQVAVIAGNLDLAEVIK 295
P VA + DL +++
Sbjct: 893 LAPADVAHQRNHWDLLTLLE 912
>BX284927-1|CAM25850.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 79.4 bits (187), Expect = 3e-14
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Query: 128 LVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNK 186
L++GGA T G T +H A + A + LLE GA+PN D G TPL+ +V
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 187 TDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
+C+ LL T + A G + A R + V+ L+ AD+ AR+ G T
Sbjct: 1679 ARE-VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTA 1737
Query: 246 LHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LH A AR LL G DK+A + QTP +A G +++A+++
Sbjct: 1738 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLL 1786
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/200 (30%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G P H TGETPL +AA P L+ GA + R G T +H AV ++ E
Sbjct: 1623 GACPQAHTVGTGETPLHLAARFSRPTAAR-RLLEAGANPNQPDRAGRTPLHAAVAADARE 1681
Query: 157 AVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+ LL + + + G TPL L+ + L+ E L+ A +GA D G +H
Sbjct: 1682 VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLV-EELIAAQADVGARDKWGKTALHW 1740
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A + LL GAD +A++ TPL + A A+ LL G +E + A
Sbjct: 1741 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 1800
Query: 276 QTPYQVAVIAGNLDLAEVIK 295
P VA + DL +++
Sbjct: 1801 LAPADVAHQRNHWDLLTLLE 1820
>BX284686-1|CAM26209.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 79.4 bits (187), Expect = 3e-14
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Query: 128 LVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNK 186
L++GGA T G T +H A + A + LLE GA+PN D G TPL+ +V
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 187 TDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
+C+ LL T + A G + A R + V+ L+ AD+ AR+ G T
Sbjct: 1679 ARE-VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTA 1737
Query: 246 LHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LH A AR LL G DK+A + QTP +A G +++A+++
Sbjct: 1738 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLL 1786
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/200 (30%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G P H TGETPL +AA P L+ GA + R G T +H AV ++ E
Sbjct: 1623 GACPQAHTVGTGETPLHLAARFSRPTAAR-RLLEAGANPNQPDRAGRTPLHAAVAADARE 1681
Query: 157 AVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+ LL + + + G TPL L+ + L+ E L+ A +GA D G +H
Sbjct: 1682 VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLV-EELIAAQADVGARDKWGKTALHW 1740
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A + LL GAD +A++ TPL + A A+ LL G +E + A
Sbjct: 1741 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 1800
Query: 276 QTPYQVAVIAGNLDLAEVIK 295
P VA + DL +++
Sbjct: 1801 LAPADVAHQRNHWDLLTLLE 1820
>BC114476-1|AAI14477.1| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 79.4 bits (187), Expect = 3e-14
Identities = 58/174 (33%), Positives = 82/174 (47%), Gaps = 2/174 (1%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
+TPL IAA K+ K ALV + ++ R G TA+H A E VK LL GA+
Sbjct: 141 QTPLHIAAANKA-VKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANI 199
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N D K ++ + ++ + L+ A + D + + +H A +G++ V +L
Sbjct: 200 NAFDKKDRRAIHWAAYMGHIEVV-KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 258
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
L G DMN NA GNTPLHV N QD +L+ G N TP A
Sbjct: 259 LDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFA 312
Score = 77.4 bits (182), Expect = 1e-13
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 4/217 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G I + G+D N G TPL +A ++ L++ GA+++ + G T
Sbjct: 250 GMISVVKYLLDLGVDMN-EPNAYGNTPLHVAC-YNGQDVVVNELIDCGAIVNQKNEKGFT 307
Query: 145 AMH-RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
+H A + ++ L+ GA N K G TPL+++ + +T++ A I
Sbjct: 308 PLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSR-SQTIIQSGAVID 366
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D G +H A R G ++ L+ GAD R G PLH+ A++ C R+LL
Sbjct: 367 CEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLS 426
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G D + + +T A GNL+ ++ N +D
Sbjct: 427 SGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGAD 463
Score = 76.2 bits (179), Expect = 3e-13
Identities = 59/216 (27%), Positives = 99/216 (45%), Gaps = 3/216 (1%)
Query: 79 LEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYR 138
++ + +G D++ K D NF E TPL AA L A+I+ L+ GA ++ +
Sbjct: 46 VQAIFNGDPDEVRALIFKKEDVNFQDNEK-RTPLHAAAYL-GDAEIIELLILSGARVNAK 103
Query: 139 TRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHD 198
T +HRAV S EAV+ LL+ A N +D TPL+++ NK E L+
Sbjct: 104 DSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKA-VKCAEALVPL 162
Query: 199 HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCA 258
+ + +D G +H A +G + V LL GA++NA + +H A
Sbjct: 163 LSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVV 222
Query: 259 RQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ L+ G + + + TP A +G + + + +
Sbjct: 223 KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 258
Score = 70.9 bits (166), Expect = 1e-11
Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 4/200 (2%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
THG + + G D N ++ G+TPL + A L ++ GA++D ++G
Sbjct: 316 THGALC-LELLVGNGADVNMKSKD-GKTPLHMTA-LHGRFSRSQTIIQSGAVIDCEDKNG 372
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
+T +H A + TL+ GA + G+ PL+L+ + C LL I
Sbjct: 373 NTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDI 431
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D G +H A G ++ ++ LL GAD N ++ G +PLH A N C L+
Sbjct: 432 DTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 491
Query: 263 FRGCDKEALNFANQTPYQVA 282
G L+ TP A
Sbjct: 492 GSGASVNDLDERGCTPLHYA 511
Score = 69.3 bits (162), Expect = 3e-11
Identities = 49/182 (26%), Positives = 78/182 (42%), Gaps = 5/182 (2%)
Query: 110 TPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
TPL AA G+ S K L+ L G ++ G+T +H A V L++ GA
Sbjct: 241 TPLHAAASSGMISVVKYLLDL---GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAI 297
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N K+ KG TPL+ + + L E L+ + A + G +H +G
Sbjct: 298 VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQT 357
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
++ GA ++ + +GNTPLH+ A + L+ G D P +A ++G
Sbjct: 358 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 417
Query: 288 LD 289
D
Sbjct: 418 SD 419
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/201 (27%), Positives = 94/201 (46%), Gaps = 12/201 (5%)
Query: 115 AAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK 174
AA + L L+N GA + + + G + +H A + + + L+ GAS N D +
Sbjct: 444 AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDER 503
Query: 175 GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG------LVQH---V 225
G TPL+ + T+ TD E LL + A G D QG+ VH + G L+ +
Sbjct: 504 GCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPL 563
Query: 226 DHLL-FYGADM--NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
D L+ G DM ++ N + +PLH+ A + L+ D + N + +TP +A
Sbjct: 564 DVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLA 623
Query: 283 VIAGNLDLAEVIKNYKSDEIV 303
G+++ +V+ N + +V
Sbjct: 624 AFKGHVECVDVLINQGASILV 644
Score = 64.9 bits (151), Expect = 7e-10
Identities = 41/167 (24%), Positives = 85/167 (50%), Gaps = 3/167 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
++++ + T +H A E ++ L+ GA N KD K LTPL+ +V + ++ + +
Sbjct: 67 VNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAV-QV 125
Query: 195 LLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
LL A + A D + WQ +H A N V+ + L+ +++N + +G T LH A +
Sbjct: 126 LLKHSADVNARD-KNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSG 184
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ LL RG + A + ++ A G++++ +++ ++ ++
Sbjct: 185 HGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAE 231
Score = 63.3 bits (147), Expect = 2e-09
Identities = 51/151 (33%), Positives = 75/151 (49%), Gaps = 12/151 (7%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALL---DYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
+G TPL +AA K + + L+N GA + DY + T +H A E ++ L+
Sbjct: 615 SGRTPLDLAA-FKGHVECVDVLINQGASILVKDYILK--RTPIHAAATNGHSECLRLLIG 671
Query: 164 LGASPN---YKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRN 219
N +DG G TPL LSV N TD + +LL+ A + A D G +H+
Sbjct: 672 NAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVY--SLLNKGANVDAKDKWGRTALHRGAVT 729
Query: 220 GLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
G + VD LL +GA R++ G TP+H+ A
Sbjct: 730 GHEECVDALLQHGAKCLLRDSRGRTPIHLSA 760
Score = 62.5 bits (145), Expect = 4e-09
Identities = 47/177 (26%), Positives = 81/177 (45%), Gaps = 2/177 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL A S + + L+ A ++ R ++ T +H A +++ + L+ L ++ N
Sbjct: 109 TPLHRAVASCSEEAVQV-LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVN 167
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
D G T L+ + + ++ + LL A I A D + + +H A G ++ V L+
Sbjct: 168 VSDRAGRTALHHAAFSGHGEMV-KLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV 226
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
+GA++ ++ TPLH A + S + LL G D N TP VA G
Sbjct: 227 SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNG 283
Score = 55.6 bits (128), Expect = 4e-07
Identities = 53/183 (28%), Positives = 79/183 (43%), Gaps = 6/183 (3%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
+PL +AA + L LV LD R G T + A K +E V L+ GAS
Sbjct: 585 SPLHLAA-YHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 643
Query: 170 YKDG-KGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ---GWQEVHQACRNGLVQHV 225
KD TP++ + TN L L+ + A D+Q G + + NG V
Sbjct: 644 VKDYILKRTPIHAAATNGHSECL-RLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCV 702
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA+++A++ G T LH AV + C LL G + +TP ++
Sbjct: 703 YSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAAC 762
Query: 286 GNL 288
G++
Sbjct: 763 GHI 765
Score = 45.2 bits (102), Expect = 6e-04
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 17/207 (8%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAV---EKNSLEAVKT-- 160
E G TPL AA + K L L+ A R + G A+H + + L+ + +
Sbjct: 502 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 561
Query: 161 ----LLELGASPNYKDGKG---LTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEV 213
L+E + D ++PL+L+ + L E L+ + + G +
Sbjct: 562 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQAL-EVLVQSLLDLDVRNSSGRTPL 620
Query: 214 HQACRNGLVQHVDHLLFYGADMNARN-ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
A G V+ VD L+ GA + ++ TP+H A N C R L+ + A++
Sbjct: 621 DLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVD 680
Query: 273 FAN---QTPYQVAVIAGNLDLAEVIKN 296
+ QTP ++V+ G+ D + N
Sbjct: 681 IQDGNGQTPLMLSVLNGHTDCVYSLLN 707
Score = 33.9 bits (74), Expect = 1.4
Identities = 25/102 (24%), Positives = 41/102 (40%)
Query: 199 HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCA 258
H+ L + + QA NG V L+F D+N ++ TPLH A
Sbjct: 31 HSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEII 90
Query: 259 RQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L+ G A + TP AV + + + +V+ + +D
Sbjct: 91 ELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSAD 132
>BC113868-1|AAI13869.1| 782|Homo sapiens ANKRD28 protein protein.
Length = 782
Score = 79.4 bits (187), Expect = 3e-14
Identities = 58/174 (33%), Positives = 82/174 (47%), Gaps = 2/174 (1%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
+TPL IAA K+ K ALV + ++ R G TA+H A E VK LL GA+
Sbjct: 138 QTPLHIAAANKA-VKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANI 196
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N D K ++ + ++ + L+ A + D + + +H A +G++ V +L
Sbjct: 197 NAFDKKDRRAIHWAAYMGHIEVV-KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 255
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
L G DMN NA GNTPLHV N QD +L+ G N TP A
Sbjct: 256 LDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFA 309
Score = 78.6 bits (185), Expect = 5e-14
Identities = 64/231 (27%), Positives = 106/231 (45%), Gaps = 6/231 (2%)
Query: 67 KALHSRAN---LRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAK 123
K+LHS + L ++ + +G D++ K D NF E TPL AA L A+
Sbjct: 28 KSLHSPPSGNVLPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEK-RTPLHAAAYL-GDAE 85
Query: 124 ILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV 183
I+ L+ GA ++ + T +HRAV S EAV+ LL+ A N +D TPL+++
Sbjct: 86 IIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAA 145
Query: 184 TNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGN 243
NK E L+ + + +D G +H A +G + V LL GA++NA +
Sbjct: 146 ANKA-VKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDR 204
Query: 244 TPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+H A + L+ G + + + TP A +G + + + +
Sbjct: 205 RAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 255
Score = 77.4 bits (182), Expect = 1e-13
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 4/217 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G I + G+D N G TPL +A ++ L++ GA+++ + G T
Sbjct: 247 GMISVVKYLLDLGVDMN-EPNAYGNTPLHVAC-YNGQDVVVNELIDCGAIVNQKNEKGFT 304
Query: 145 AMH-RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
+H A + ++ L+ GA N K G TPL+++ + +T++ A I
Sbjct: 305 PLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSR-SQTIIQSGAVID 363
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D G +H A R G ++ L+ GAD R G PLH+ A++ C R+LL
Sbjct: 364 CEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLS 423
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G D + + +T A GNL+ ++ N +D
Sbjct: 424 SGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGAD 460
Score = 70.9 bits (166), Expect = 1e-11
Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 4/200 (2%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
THG + + G D N ++ G+TPL + A L ++ GA++D ++G
Sbjct: 313 THGALC-LELLVGNGADVNMKSKD-GKTPLHMTA-LHGRFSRSQTIIQSGAVIDCEDKNG 369
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
+T +H A + TL+ GA + G+ PL+L+ + C LL I
Sbjct: 370 NTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDI 428
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D G +H A G ++ ++ LL GAD N ++ G +PLH A N C L+
Sbjct: 429 DTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 488
Query: 263 FRGCDKEALNFANQTPYQVA 282
G L+ TP A
Sbjct: 489 GSGASVNDLDERGCTPLHYA 508
Score = 69.3 bits (162), Expect = 3e-11
Identities = 49/182 (26%), Positives = 78/182 (42%), Gaps = 5/182 (2%)
Query: 110 TPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
TPL AA G+ S K L+ L G ++ G+T +H A V L++ GA
Sbjct: 238 TPLHAAASSGMISVVKYLLDL---GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAI 294
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N K+ KG TPL+ + + L E L+ + A + G +H +G
Sbjct: 295 VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQT 354
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
++ GA ++ + +GNTPLH+ A + L+ G D P +A ++G
Sbjct: 355 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 414
Query: 288 LD 289
D
Sbjct: 415 SD 416
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/201 (27%), Positives = 94/201 (46%), Gaps = 12/201 (5%)
Query: 115 AAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK 174
AA + L L+N GA + + + G + +H A + + + L+ GAS N D +
Sbjct: 441 AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDER 500
Query: 175 GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG------LVQH---V 225
G TPL+ + T+ TD E LL + A G D QG+ VH + G L+ +
Sbjct: 501 GCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPL 560
Query: 226 DHLL-FYGADM--NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
D L+ G DM ++ N + +PLH+ A + L+ D + N + +TP +A
Sbjct: 561 DVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLA 620
Query: 283 VIAGNLDLAEVIKNYKSDEIV 303
G+++ +V+ N + +V
Sbjct: 621 AFKGHVECVDVLINQGASILV 641
Score = 64.9 bits (151), Expect = 7e-10
Identities = 41/167 (24%), Positives = 85/167 (50%), Gaps = 3/167 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
++++ + T +H A E ++ L+ GA N KD K LTPL+ +V + ++ + +
Sbjct: 64 VNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAV-QV 122
Query: 195 LLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
LL A + A D + WQ +H A N V+ + L+ +++N + +G T LH A +
Sbjct: 123 LLKHSADVNARD-KNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSG 181
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ LL RG + A + ++ A G++++ +++ ++ ++
Sbjct: 182 HGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAE 228
Score = 63.3 bits (147), Expect = 2e-09
Identities = 51/151 (33%), Positives = 75/151 (49%), Gaps = 12/151 (7%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALL---DYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
+G TPL +AA K + + L+N GA + DY + T +H A E ++ L+
Sbjct: 612 SGRTPLDLAA-FKGHVECVDVLINQGASILVKDYILK--RTPIHAAATNGHSECLRLLIG 668
Query: 164 LGASPN---YKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRN 219
N +DG G TPL LSV N TD + +LL+ A + A D G +H+
Sbjct: 669 NAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVY--SLLNKGANVDAKDKWGRTALHRGAVT 726
Query: 220 GLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
G + VD LL +GA R++ G TP+H+ A
Sbjct: 727 GHEECVDALLQHGAKCLLRDSRGRTPIHLSA 757
Score = 62.5 bits (145), Expect = 4e-09
Identities = 47/177 (26%), Positives = 81/177 (45%), Gaps = 2/177 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL A S + + L+ A ++ R ++ T +H A +++ + L+ L ++ N
Sbjct: 106 TPLHRAVASCSEEAVQV-LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVN 164
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
D G T L+ + + ++ + LL A I A D + + +H A G ++ V L+
Sbjct: 165 VSDRAGRTALHHAAFSGHGEMV-KLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV 223
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
+GA++ ++ TPLH A + S + LL G D N TP VA G
Sbjct: 224 SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNG 280
Score = 55.6 bits (128), Expect = 4e-07
Identities = 53/183 (28%), Positives = 79/183 (43%), Gaps = 6/183 (3%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
+PL +AA + L LV LD R G T + A K +E V L+ GAS
Sbjct: 582 SPLHLAA-YHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 640
Query: 170 YKDG-KGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ---GWQEVHQACRNGLVQHV 225
KD TP++ + TN L L+ + A D+Q G + + NG V
Sbjct: 641 VKDYILKRTPIHAAATNGHSECL-RLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCV 699
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA+++A++ G T LH AV + C LL G + +TP ++
Sbjct: 700 YSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAAC 759
Query: 286 GNL 288
G++
Sbjct: 760 GHI 762
Score = 45.2 bits (102), Expect = 6e-04
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 17/207 (8%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAV---EKNSLEAVKT-- 160
E G TPL AA + K L L+ A R + G A+H + + L+ + +
Sbjct: 499 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 558
Query: 161 ----LLELGASPNYKDGKG---LTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEV 213
L+E + D ++PL+L+ + L E L+ + + G +
Sbjct: 559 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQAL-EVLVQSLLDLDVRNSSGRTPL 617
Query: 214 HQACRNGLVQHVDHLLFYGADMNARN-ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
A G V+ VD L+ GA + ++ TP+H A N C R L+ + A++
Sbjct: 618 DLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVD 677
Query: 273 FAN---QTPYQVAVIAGNLDLAEVIKN 296
+ QTP ++V+ G+ D + N
Sbjct: 678 IQDGNGQTPLMLSVLNGHTDCVYSLLN 704
Score = 40.3 bits (90), Expect = 0.016
Identities = 32/145 (22%), Positives = 56/145 (38%)
Query: 150 VEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQG 209
VE S + L + S + + P + DP L+ + D +
Sbjct: 12 VEDESPAFISKLPQENKSLHSPPSGNVLPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEK 71
Query: 210 WQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKE 269
+H A G + ++ L+ GA +NA+++ TPLH + + + LL D
Sbjct: 72 RTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVN 131
Query: 270 ALNFANQTPYQVAVIAGNLDLAEVI 294
A + QTP +A + AE +
Sbjct: 132 ARDKNWQTPLHIAAANKAVKCAEAL 156
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/86 (26%), Positives = 36/86 (41%)
Query: 215 QACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFA 274
QA NG V L+F D+N ++ TPLH A L+ G A +
Sbjct: 44 QAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSK 103
Query: 275 NQTPYQVAVIAGNLDLAEVIKNYKSD 300
TP AV + + + +V+ + +D
Sbjct: 104 WLTPLHRAVASCSEEAVQVLLKHSAD 129
>BC106948-1|AAI06949.2| 785|Homo sapiens ANKRD28 protein protein.
Length = 785
Score = 79.4 bits (187), Expect = 3e-14
Identities = 58/174 (33%), Positives = 82/174 (47%), Gaps = 2/174 (1%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
+TPL IAA K+ K ALV + ++ R G TA+H A E VK LL GA+
Sbjct: 141 QTPLHIAAANKA-VKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANI 199
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N D K ++ + ++ + L+ A + D + + +H A +G++ V +L
Sbjct: 200 NAFDKKDRRAIHWAAYMGHIEVV-KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 258
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
L G DMN NA GNTPLHV N QD +L+ G N TP A
Sbjct: 259 LDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFA 312
Score = 77.4 bits (182), Expect = 1e-13
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 4/217 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G I + G+D N G TPL +A ++ L++ GA+++ + G T
Sbjct: 250 GMISVVKYLLDLGVDMN-EPNAYGNTPLHVAC-YNGQDVVVNELIDCGAIVNQKNEKGFT 307
Query: 145 AMH-RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
+H A + ++ L+ GA N K G TPL+++ + +T++ A I
Sbjct: 308 PLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSR-SQTIIQSGAVID 366
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D G +H A R G ++ L+ GAD R G PLH+ A++ C R+LL
Sbjct: 367 CEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLS 426
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G D + + +T A GNL+ ++ N +D
Sbjct: 427 SGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGAD 463
Score = 76.2 bits (179), Expect = 3e-13
Identities = 59/216 (27%), Positives = 99/216 (45%), Gaps = 3/216 (1%)
Query: 79 LEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYR 138
++ + +G D++ K D NF E TPL AA L A+I+ L+ GA ++ +
Sbjct: 46 VQAIFNGDPDEVRALIFKKEDVNFQDNEK-RTPLHAAAYL-GDAEIIELLILSGARVNAK 103
Query: 139 TRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHD 198
T +HRAV S EAV+ LL+ A N +D TPL+++ NK E L+
Sbjct: 104 DSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKA-VKCAEALVPL 162
Query: 199 HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCA 258
+ + +D G +H A +G + V LL GA++NA + +H A
Sbjct: 163 LSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVV 222
Query: 259 RQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ L+ G + + + TP A +G + + + +
Sbjct: 223 KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 258
Score = 70.9 bits (166), Expect = 1e-11
Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 4/200 (2%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
THG + + G D N ++ G+TPL + A L ++ GA++D ++G
Sbjct: 316 THGALC-LELLVGNGADVNMKSKD-GKTPLHMTA-LHGRFSRSQTIIQSGAVIDCEDKNG 372
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
+T +H A + TL+ GA + G+ PL+L+ + C LL I
Sbjct: 373 NTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDI 431
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D G +H A G ++ ++ LL GAD N ++ G +PLH A N C L+
Sbjct: 432 DTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 491
Query: 263 FRGCDKEALNFANQTPYQVA 282
G L+ TP A
Sbjct: 492 GSGASVNDLDERGCTPLHYA 511
Score = 69.3 bits (162), Expect = 3e-11
Identities = 49/182 (26%), Positives = 78/182 (42%), Gaps = 5/182 (2%)
Query: 110 TPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
TPL AA G+ S K L+ L G ++ G+T +H A V L++ GA
Sbjct: 241 TPLHAAASSGMISVVKYLLDL---GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAI 297
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N K+ KG TPL+ + + L E L+ + A + G +H +G
Sbjct: 298 VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQT 357
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
++ GA ++ + +GNTPLH+ A + L+ G D P +A ++G
Sbjct: 358 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 417
Query: 288 LD 289
D
Sbjct: 418 SD 419
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/201 (27%), Positives = 94/201 (46%), Gaps = 12/201 (5%)
Query: 115 AAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK 174
AA + L L+N GA + + + G + +H A + + + L+ GAS N D +
Sbjct: 444 AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDER 503
Query: 175 GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG------LVQH---V 225
G TPL+ + T+ TD E LL + A G D QG+ VH + G L+ +
Sbjct: 504 GCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPL 563
Query: 226 DHLL-FYGADM--NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
D L+ G DM ++ N + +PLH+ A + L+ D + N + +TP +A
Sbjct: 564 DVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLA 623
Query: 283 VIAGNLDLAEVIKNYKSDEIV 303
G+++ +V+ N + +V
Sbjct: 624 AFKGHVECVDVLINQGASILV 644
Score = 64.9 bits (151), Expect = 7e-10
Identities = 41/167 (24%), Positives = 85/167 (50%), Gaps = 3/167 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
++++ + T +H A E ++ L+ GA N KD K LTPL+ +V + ++ + +
Sbjct: 67 VNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAV-QV 125
Query: 195 LLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
LL A + A D + WQ +H A N V+ + L+ +++N + +G T LH A +
Sbjct: 126 LLKHSADVNARD-KNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSG 184
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ LL RG + A + ++ A G++++ +++ ++ ++
Sbjct: 185 HGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAE 231
Score = 63.3 bits (147), Expect = 2e-09
Identities = 51/151 (33%), Positives = 75/151 (49%), Gaps = 12/151 (7%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALL---DYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
+G TPL +AA K + + L+N GA + DY + T +H A E ++ L+
Sbjct: 615 SGRTPLDLAA-FKGHVECVDVLINQGASILVKDYILK--RTPIHAAATNGHSECLRLLIG 671
Query: 164 LGASPN---YKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRN 219
N +DG G TPL LSV N TD + +LL+ A + A D G +H+
Sbjct: 672 NAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVY--SLLNKGANVDAKDKWGRTALHRGAVT 729
Query: 220 GLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
G + VD LL +GA R++ G TP+H+ A
Sbjct: 730 GHEECVDALLQHGAKCLLRDSRGRTPIHLSA 760
Score = 62.5 bits (145), Expect = 4e-09
Identities = 47/177 (26%), Positives = 81/177 (45%), Gaps = 2/177 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL A S + + L+ A ++ R ++ T +H A +++ + L+ L ++ N
Sbjct: 109 TPLHRAVASCSEEAVQV-LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVN 167
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
D G T L+ + + ++ + LL A I A D + + +H A G ++ V L+
Sbjct: 168 VSDRAGRTALHHAAFSGHGEMV-KLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV 226
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
+GA++ ++ TPLH A + S + LL G D N TP VA G
Sbjct: 227 SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNG 283
Score = 55.6 bits (128), Expect = 4e-07
Identities = 53/183 (28%), Positives = 79/183 (43%), Gaps = 6/183 (3%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
+PL +AA + L LV LD R G T + A K +E V L+ GAS
Sbjct: 585 SPLHLAA-YHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASIL 643
Query: 170 YKDG-KGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ---GWQEVHQACRNGLVQHV 225
KD TP++ + TN L L+ + A D+Q G + + NG V
Sbjct: 644 VKDYILKRTPIHAAATNGHSECL-RLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCV 702
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA+++A++ G T LH AV + C LL G + +TP ++
Sbjct: 703 YSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAKCLLRDSRGRTPIHLSAAC 762
Query: 286 GNL 288
G++
Sbjct: 763 GHI 765
Score = 45.2 bits (102), Expect = 6e-04
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 17/207 (8%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAV---EKNSLEAVKT-- 160
E G TPL AA + K L L+ A R + G A+H + + L+ + +
Sbjct: 502 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 561
Query: 161 ----LLELGASPNYKDGKG---LTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEV 213
L+E + D ++PL+L+ + L E L+ + + G +
Sbjct: 562 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQAL-EVLVQSLLDLDVRNSSGRTPL 620
Query: 214 HQACRNGLVQHVDHLLFYGADMNARN-ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
A G V+ VD L+ GA + ++ TP+H A N C R L+ + A++
Sbjct: 621 DLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVD 680
Query: 273 FAN---QTPYQVAVIAGNLDLAEVIKN 296
+ QTP ++V+ G+ D + N
Sbjct: 681 IQDGNGQTPLMLSVLNGHTDCVYSLLN 707
Score = 33.9 bits (74), Expect = 1.4
Identities = 25/102 (24%), Positives = 41/102 (40%)
Query: 199 HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCA 258
H+ L + + QA NG V L+F D+N ++ TPLH A
Sbjct: 31 HSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEII 90
Query: 259 RQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L+ G A + TP AV + + + +V+ + +D
Sbjct: 91 ELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSAD 132
>AL845509-1|CAI18564.1| 2003|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2003
Score = 79.4 bits (187), Expect = 3e-14
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Query: 128 LVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNK 186
L++GGA T G T +H A + A + LLE GA+PN D G TPL+ +V
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 187 TDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
+C+ LL T + A G + A R + V+ L+ AD+ AR+ G T
Sbjct: 1679 ARE-VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTA 1737
Query: 246 LHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LH A AR LL G DK+A + QTP +A G +++A+++
Sbjct: 1738 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLL 1786
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/200 (30%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G P H TGETPL +AA P L+ GA + R G T +H AV ++ E
Sbjct: 1623 GACPQAHTVGTGETPLHLAARFSRPTAAR-RLLEAGANPNQPDRAGRTPLHAAVAADARE 1681
Query: 157 AVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+ LL + + + G TPL L+ + L+ E L+ A +GA D G +H
Sbjct: 1682 VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLV-EELIAAQADVGARDKWGKTALHW 1740
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A + LL GAD +A++ TPL + A A+ LL G +E + A
Sbjct: 1741 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 1800
Query: 276 QTPYQVAVIAGNLDLAEVIK 295
P VA + DL +++
Sbjct: 1801 LAPADVAHQRNHWDLLTLLE 1820
>AL845464-12|CAI41803.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 79.4 bits (187), Expect = 3e-14
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Query: 128 LVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNK 186
L++GGA T G T +H A + A + LLE GA+PN D G TPL+ +V
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 187 TDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
+C+ LL T + A G + A R + V+ L+ AD+ AR+ G T
Sbjct: 1679 ARE-VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTA 1737
Query: 246 LHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LH A AR LL G DK+A + QTP +A G +++A+++
Sbjct: 1738 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLL 1786
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/200 (30%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G P H TGETPL +AA P L+ GA + R G T +H AV ++ E
Sbjct: 1623 GACPQAHTVGTGETPLHLAARFSRPTAAR-RLLEAGANPNQPDRAGRTPLHAAVAADARE 1681
Query: 157 AVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+ LL + + + G TPL L+ + L+ E L+ A +GA D G +H
Sbjct: 1682 VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLV-EELIAAQADVGARDKWGKTALHW 1740
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A + LL GAD +A++ TPL + A A+ LL G +E + A
Sbjct: 1741 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 1800
Query: 276 QTPYQVAVIAGNLDLAEVIK 295
P VA + DL +++
Sbjct: 1801 LAPADVAHQRNHWDLLTLLE 1820
>AL662884-27|CAI18362.1| 2003|Homo sapiens Notch homolog 4
(Drosophila) protein.
Length = 2003
Score = 79.4 bits (187), Expect = 3e-14
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Query: 128 LVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNK 186
L++GGA T G T +H A + A + LLE GA+PN D G TPL+ +V
Sbjct: 1619 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1678
Query: 187 TDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
+C+ LL T + A G + A R + V+ L+ AD+ AR+ G T
Sbjct: 1679 ARE-VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTA 1737
Query: 246 LHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LH A AR LL G DK+A + QTP +A G +++A+++
Sbjct: 1738 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLL 1786
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/200 (30%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G P H TGETPL +AA P L+ GA + R G T +H AV ++ E
Sbjct: 1623 GACPQAHTVGTGETPLHLAARFSRPTAAR-RLLEAGANPNQPDRAGRTPLHAAVAADARE 1681
Query: 157 AVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+ LL + + + G TPL L+ + L+ E L+ A +GA D G +H
Sbjct: 1682 VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLV-EELIAAQADVGARDKWGKTALHW 1740
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A + LL GAD +A++ TPL + A A+ LL G +E + A
Sbjct: 1741 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 1800
Query: 276 QTPYQVAVIAGNLDLAEVIK 295
P VA + DL +++
Sbjct: 1801 LAPADVAHQRNHWDLLTLLE 1820
>AL662830-9|CAI17543.1| 2005|Homo sapiens Notch homolog 4 (Drosophila)
protein.
Length = 2005
Score = 79.4 bits (187), Expect = 3e-14
Identities = 56/169 (33%), Positives = 82/169 (48%), Gaps = 3/169 (1%)
Query: 128 LVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNK 186
L++GGA T G T +H A + A + LLE GA+PN D G TPL+ +V
Sbjct: 1621 LLDGGACPQAHTVGTGETPLHLAARFSRPTAARRLLEAGANPNQPDRAGRTPLHAAVAAD 1680
Query: 187 TDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
+C+ LL T + A G + A R + V+ L+ AD+ AR+ G T
Sbjct: 1681 ARE-VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLVEELIAAQADVGARDKWGKTA 1739
Query: 246 LHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LH A AR LL G DK+A + QTP +A G +++A+++
Sbjct: 1740 LHWAAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLL 1788
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/200 (30%), Positives = 88/200 (44%), Gaps = 3/200 (1%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G P H TGETPL +AA P L+ GA + R G T +H AV ++ E
Sbjct: 1625 GACPQAHTVGTGETPLHLAARFSRPTAAR-RLLEAGANPNQPDRAGRTPLHAAVAADARE 1683
Query: 157 AVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+ LL + + + G TPL L+ + L+ E L+ A +GA D G +H
Sbjct: 1684 VCQLLLRSRQTAVDARTEDGTTPLMLAARLAVEDLV-EELIAAQADVGARDKWGKTALHW 1742
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A + LL GAD +A++ TPL + A A+ LL G +E + A
Sbjct: 1743 AAAVNNARAARSLLQAGADKDAQDNREQTPLFLAAREGAVEVAQLLLGLGAARELRDQAG 1802
Query: 276 QTPYQVAVIAGNLDLAEVIK 295
P VA + DL +++
Sbjct: 1803 LAPADVAHQRNHWDLLTLLE 1822
>AK126888-1|BAC86737.1| 687|Homo sapiens protein ( Homo sapiens
cDNA FLJ44940 fis, clone BRAMY4000915, weakly similar
to Ankyrin 1. ).
Length = 687
Score = 79.4 bits (187), Expect = 3e-14
Identities = 58/174 (33%), Positives = 82/174 (47%), Gaps = 2/174 (1%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
+TPL IAA K+ K ALV + ++ R G TA+H A E VK LL GA+
Sbjct: 141 QTPLHIAAANKA-VKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANI 199
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N D K ++ + ++ + L+ A + D + + +H A +G++ V +L
Sbjct: 200 NAFDKKDRRAIHWAAYMGHIEVV-KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 258
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
L G DMN NA GNTPLHV N QD +L+ G N TP A
Sbjct: 259 LDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFA 312
Score = 77.4 bits (182), Expect = 1e-13
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 4/217 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G I + G+D N G TPL +A ++ L++ GA+++ + G T
Sbjct: 250 GMISVVKYLLDLGVDMN-EPNAYGNTPLHVAC-YNGQDVVVNELIDCGAIVNQKNEKGFT 307
Query: 145 AMH-RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
+H A + ++ L+ GA N K G TPL+++ + +T++ A I
Sbjct: 308 PLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSR-SQTIIQSGAVID 366
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D G +H A R G ++ L+ GAD R G PLH+ A++ C R+LL
Sbjct: 367 CEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLS 426
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G D + + +T A GNL+ ++ N +D
Sbjct: 427 SGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGAD 463
Score = 76.2 bits (179), Expect = 3e-13
Identities = 59/216 (27%), Positives = 99/216 (45%), Gaps = 3/216 (1%)
Query: 79 LEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYR 138
++ + +G D++ K D NF E TPL AA L A+I+ L+ GA ++ +
Sbjct: 46 VQAIFNGDPDEVRALIFKKEDVNFQDNEK-RTPLHAAAYL-GDAEIIELLILSGARVNAK 103
Query: 139 TRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHD 198
T +HRAV S EAV+ LL+ A N +D TPL+++ NK E L+
Sbjct: 104 DSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIAAANKA-VKCAEALVPL 162
Query: 199 HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCA 258
+ + +D G +H A +G + V LL GA++NA + +H A
Sbjct: 163 LSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVV 222
Query: 259 RQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ L+ G + + + TP A +G + + + +
Sbjct: 223 KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 258
Score = 70.9 bits (166), Expect = 1e-11
Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 4/200 (2%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
THG + + G D N ++ G+TPL + A L ++ GA++D ++G
Sbjct: 316 THGALC-LELLVGNGADVNMKSKD-GKTPLHMTA-LHGRFSRSQTIIQSGAVIDCEDKNG 372
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
+T +H A + TL+ GA + G+ PL+L+ + C LL I
Sbjct: 373 NTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDI 431
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D G +H A G ++ ++ LL GAD N ++ G +PLH A N C L+
Sbjct: 432 DTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 491
Query: 263 FRGCDKEALNFANQTPYQVA 282
G L+ TP A
Sbjct: 492 GSGASVNDLDERGCTPLHYA 511
Score = 69.3 bits (162), Expect = 3e-11
Identities = 49/182 (26%), Positives = 78/182 (42%), Gaps = 5/182 (2%)
Query: 110 TPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
TPL AA G+ S K L+ L G ++ G+T +H A V L++ GA
Sbjct: 241 TPLHAAASSGMISVVKYLLDL---GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAI 297
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N K+ KG TPL+ + + L E L+ + A + G +H +G
Sbjct: 298 VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQT 357
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
++ GA ++ + +GNTPLH+ A + L+ G D P +A ++G
Sbjct: 358 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 417
Query: 288 LD 289
D
Sbjct: 418 SD 419
Score = 69.3 bits (162), Expect = 3e-11
Identities = 55/201 (27%), Positives = 94/201 (46%), Gaps = 12/201 (5%)
Query: 115 AAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK 174
AA + L L+N GA + + + G + +H A + + + L+ GAS N D +
Sbjct: 444 AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDER 503
Query: 175 GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG------LVQH---V 225
G TPL+ + T+ TD E LL + A G D QG+ VH + G L+ +
Sbjct: 504 GCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASETPL 563
Query: 226 DHLL-FYGADM--NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
D L+ G DM ++ N + +PLH+ A + L+ D + N + +TP +A
Sbjct: 564 DVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLA 623
Query: 283 VIAGNLDLAEVIKNYKSDEIV 303
G+++ +V+ N + +V
Sbjct: 624 AFKGHVECVDVLINQGASILV 644
Score = 64.9 bits (151), Expect = 7e-10
Identities = 41/167 (24%), Positives = 85/167 (50%), Gaps = 3/167 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
++++ + T +H A E ++ L+ GA N KD K LTPL+ +V + ++ + +
Sbjct: 67 VNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAV-QV 125
Query: 195 LLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
LL A + A D + WQ +H A N V+ + L+ +++N + +G T LH A +
Sbjct: 126 LLKHSADVNARD-KNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSG 184
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ LL RG + A + ++ A G++++ +++ ++ ++
Sbjct: 185 HGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAE 231
Score = 62.5 bits (145), Expect = 4e-09
Identities = 47/177 (26%), Positives = 81/177 (45%), Gaps = 2/177 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL A S + + L+ A ++ R ++ T +H A +++ + L+ L ++ N
Sbjct: 109 TPLHRAVASCSEEAVQV-LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVN 167
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
D G T L+ + + ++ + LL A I A D + + +H A G ++ V L+
Sbjct: 168 VSDRAGRTALHHAAFSGHGEMV-KLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV 226
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
+GA++ ++ TPLH A + S + LL G D N TP VA G
Sbjct: 227 SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNG 283
Score = 37.5 bits (83), Expect = 0.11
Identities = 44/170 (25%), Positives = 68/170 (40%), Gaps = 14/170 (8%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKN-----SLEAVKT 160
E G TPL AA + K L L+ A R + G A+H + L A +T
Sbjct: 502 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGVRDKQGYNAVHYSAAYGHRLCLQLIASET 561
Query: 161 ----LLELGASPNYKDGKG---LTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEV 213
L+E + D ++PL+L+ + L E L+ + + G +
Sbjct: 562 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQAL-EVLVQSLLDLDVRNSSGRTPL 620
Query: 214 HQACRNGLVQHVDHLLFYGADMNARN-ASGNTPLHVCAVNAQDSCARQLL 262
A G V+ VD L+ GA + ++ TP+H A N C R L+
Sbjct: 621 DLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLI 670
Score = 33.9 bits (74), Expect = 1.4
Identities = 25/102 (24%), Positives = 41/102 (40%)
Query: 199 HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCA 258
H+ L + + QA NG V L+F D+N ++ TPLH A
Sbjct: 31 HSPPSGNVLVRYPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEII 90
Query: 259 RQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L+ G A + TP AV + + + +V+ + +D
Sbjct: 91 ELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSAD 132
>AB002377-1|BAA20833.2| 1059|Homo sapiens KIAA0379 protein protein.
Length = 1059
Score = 79.4 bits (187), Expect = 3e-14
Identities = 58/174 (33%), Positives = 82/174 (47%), Gaps = 2/174 (1%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
+TPL IAA K+ K ALV + ++ R G TA+H A E VK LL GA+
Sbjct: 114 QTPLHIAAANKA-VKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANI 172
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N D K ++ + ++ + L+ A + D + + +H A +G++ V +L
Sbjct: 173 NAFDKKDRRAIHWAAYMGHIEVV-KLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 231
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
L G DMN NA GNTPLHV N QD +L+ G N TP A
Sbjct: 232 LDLGVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAIVNQKNEKGFTPLHFA 285
Score = 77.4 bits (182), Expect = 1e-13
Identities = 58/217 (26%), Positives = 96/217 (44%), Gaps = 4/217 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G I + G+D N G TPL +A ++ L++ GA+++ + G T
Sbjct: 223 GMISVVKYLLDLGVDMN-EPNAYGNTPLHVAC-YNGQDVVVNELIDCGAIVNQKNEKGFT 280
Query: 145 AMH-RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
+H A + ++ L+ GA N K G TPL+++ + +T++ A I
Sbjct: 281 PLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSR-SQTIIQSGAVID 339
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D G +H A R G ++ L+ GAD R G PLH+ A++ C R+LL
Sbjct: 340 CEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDCCRKLLS 399
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G D + + +T A GNL+ ++ N +D
Sbjct: 400 SGFDIDTPDDFGRTCLHAAAAGGNLECLNLLLNTGAD 436
Score = 76.6 bits (180), Expect = 2e-13
Identities = 62/232 (26%), Positives = 103/232 (44%), Gaps = 3/232 (1%)
Query: 63 EKTLKALHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPA 122
E T A + ++ + +G D++ K D NF E TPL AA L A
Sbjct: 3 EATAMAFLKLRDQPSLVQAIFNGDPDEVRALIFKKEDVNFQDNEK-RTPLHAAAYL-GDA 60
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
+I+ L+ GA ++ + T +HRAV S EAV+ LL+ A N +D TPL+++
Sbjct: 61 EIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAVQVLLKHSADVNARDKNWQTPLHIA 120
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
NK E L+ + + +D G +H A +G + V LL GA++NA +
Sbjct: 121 AANKA-VKCAEALVPLLSNVNVSDRAGRTALHHAAFSGHGEMVKLLLSRGANINAFDKKD 179
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+H A + L+ G + + + TP A +G + + + +
Sbjct: 180 RRAIHWAAYMGHIEVVKLLVSHGAEVTCKDKKSYTPLHAAASSGMISVVKYL 231
Score = 70.9 bits (166), Expect = 1e-11
Identities = 55/200 (27%), Positives = 86/200 (43%), Gaps = 4/200 (2%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
THG + + G D N ++ G+TPL + A L ++ GA++D ++G
Sbjct: 289 THGALC-LELLVGNGADVNMKSKD-GKTPLHMTA-LHGRFSRSQTIIQSGAVIDCEDKNG 345
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
+T +H A + TL+ GA + G+ PL+L+ + C LL I
Sbjct: 346 NTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGFSDC-CRKLLSSGFDI 404
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D G +H A G ++ ++ LL GAD N ++ G +PLH A N C L+
Sbjct: 405 DTPDDFGRTCLHAAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALV 464
Query: 263 FRGCDKEALNFANQTPYQVA 282
G L+ TP A
Sbjct: 465 GSGASVNDLDERGCTPLHYA 484
Score = 69.3 bits (162), Expect = 3e-11
Identities = 49/182 (26%), Positives = 78/182 (42%), Gaps = 5/182 (2%)
Query: 110 TPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
TPL AA G+ S K L+ L G ++ G+T +H A V L++ GA
Sbjct: 214 TPLHAAASSGMISVVKYLLDL---GVDMNEPNAYGNTPLHVACYNGQDVVVNELIDCGAI 270
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N K+ KG TPL+ + + L E L+ + A + G +H +G
Sbjct: 271 VNQKNEKGFTPLHFAAASTHGALCLELLVGNGADVNMKSKDGKTPLHMTALHGRFSRSQT 330
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
++ GA ++ + +GNTPLH+ A + L+ G D P +A ++G
Sbjct: 331 IIQSGAVIDCEDKNGNTPLHIAARYGHELLINTLITSGADTAKRGIHGMFPLHLAALSGF 390
Query: 288 LD 289
D
Sbjct: 391 SD 392
Score = 68.9 bits (161), Expect = 4e-11
Identities = 55/201 (27%), Positives = 94/201 (46%), Gaps = 12/201 (5%)
Query: 115 AAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK 174
AA + L L+N GA + + + G + +H A + + + L+ GAS N D +
Sbjct: 417 AAAAGGNLECLNLLLNTGADFNKKDKFGRSPLHYAAANCNYQCLFALVGSGASVNDLDER 476
Query: 175 GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG------LVQH---V 225
G TPL+ + T+ TD E LL + A G D QG+ VH + G L+ +
Sbjct: 477 GCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASETPL 536
Query: 226 DHLL-FYGADM--NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
D L+ G DM ++ N + +PLH+ A + L+ D + N + +TP +A
Sbjct: 537 DVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLA 596
Query: 283 VIAGNLDLAEVIKNYKSDEIV 303
G+++ +V+ N + +V
Sbjct: 597 AFKGHVECVDVLINQGASILV 617
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/198 (26%), Positives = 89/198 (44%), Gaps = 9/198 (4%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G+TPL ++ L + +L+N GA +D + + G TA+HR E V LL+ GA
Sbjct: 659 GQTPLMLSV-LNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAK 717
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA----TDLQGWQEVHQACRNGLVQ 223
+D +G TP++LS +L LL A++ A D G+ +H AC NG
Sbjct: 718 CLLRDSRGRTPIHLSAACGHIGVL-GALLQSAASMDANPATADNHGYTALHWACYNGHET 776
Query: 224 HVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL--FRGCDKEALNFANQTPYQV 281
V+ LL + +PLH +N + A L+ A + +TP
Sbjct: 777 CVE-LLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHA 835
Query: 282 AVIAGNLDLAEVIKNYKS 299
A +++ +++ ++ +
Sbjct: 836 AAFTDHVECLQLLLSHNA 853
Score = 64.9 bits (151), Expect = 7e-10
Identities = 41/167 (24%), Positives = 85/167 (50%), Gaps = 3/167 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
++++ + T +H A E ++ L+ GA N KD K LTPL+ +V + ++ + +
Sbjct: 40 VNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSKWLTPLHRAVASCSEEAV-QV 98
Query: 195 LLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
LL A + A D + WQ +H A N V+ + L+ +++N + +G T LH A +
Sbjct: 99 LLKHSADVNARD-KNWQTPLHIAAANKAVKCAEALVPLLSNVNVSDRAGRTALHHAAFSG 157
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ LL RG + A + ++ A G++++ +++ ++ ++
Sbjct: 158 HGEMVKLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLVSHGAE 204
Score = 62.5 bits (145), Expect = 4e-09
Identities = 47/177 (26%), Positives = 81/177 (45%), Gaps = 2/177 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL A S + + L+ A ++ R ++ T +H A +++ + L+ L ++ N
Sbjct: 82 TPLHRAVASCSEEAVQV-LLKHSADVNARDKNWQTPLHIAAANKAVKCAEALVPLLSNVN 140
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
D G T L+ + + ++ + LL A I A D + + +H A G ++ V L+
Sbjct: 141 VSDRAGRTALHHAAFSGHGEMV-KLLLSRGANINAFDKKDRRAIHWAAYMGHIEVVKLLV 199
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
+GA++ ++ TPLH A + S + LL G D N TP VA G
Sbjct: 200 SHGAEVTCKDKKSYTPLHAAASSGMISVVKYLLDLGVDMNEPNAYGNTPLHVACYNG 256
Score = 54.0 bits (124), Expect = 1e-06
Identities = 48/176 (27%), Positives = 77/176 (43%), Gaps = 6/176 (3%)
Query: 122 AKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYL 181
A++LI + G ++++ G T +H A + +E ++ LL A N D G TPL +
Sbjct: 810 AEMLIDTL-GASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMM 868
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGAD---MNAR 238
+ N + + A + D +H AC G +L D +NA
Sbjct: 869 AAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINAT 928
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
NA+ TPLHV A N ++LL +G A++ TP A N D+A+ +
Sbjct: 929 NAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTP--ALACAPNKDVADCL 982
Score = 52.8 bits (121), Expect = 3e-06
Identities = 45/148 (30%), Positives = 65/148 (43%), Gaps = 4/148 (2%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE-LGA 166
G TPL AA + L L++ A ++ G T + A E V+ L+ A
Sbjct: 829 GRTPLH-AAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASA 887
Query: 167 SPNYKDGKGLTPLYLSVT--NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
+D T L+L+ + ++T LL + D I AT+ +H A RNGL
Sbjct: 888 ELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMV 947
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVN 252
V LL GA + A + +G TP CA N
Sbjct: 948 VQELLGKGASVLAVDENGYTPALACAPN 975
Score = 50.8 bits (116), Expect = 1e-05
Identities = 55/227 (24%), Positives = 92/227 (40%), Gaps = 10/227 (4%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V +G D + KG + + + G T L A + + + AL+ GA R
Sbjct: 667 VLNGHTDCVYSLLNKGANVDAK-DKWGRTALHRGA-VTGHEECVDALLQHGAKCLLRDSR 724
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGAS----PNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
G T +H + + + LL+ AS P D G T L+ + N + C LL
Sbjct: 725 GRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHET--CVELLL 782
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLL-FYGADM-NARNASGNTPLHVCAVNAQD 255
+ T+ + +H A N + L+ GA + NA ++ G TPLH A
Sbjct: 783 EQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHV 842
Query: 256 SCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEI 302
C + LL +++ +TP +A G + E++ + S E+
Sbjct: 843 ECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAEL 889
Score = 46.8 bits (106), Expect = 2e-04
Identities = 50/191 (26%), Positives = 81/191 (42%), Gaps = 8/191 (4%)
Query: 110 TPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
TP+ AA G ++LI +D + +G T + +V + V +LL GA+
Sbjct: 625 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 684
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ KD G T L+ + + + LL A D +G +H + G + +
Sbjct: 685 VDAKDKWGRTALHRGAVTGHEECV-DALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 743
Query: 228 LLFYGADMNARNAS----GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
LL A M+A A+ G T LH N ++C LL + ++ A +P AV
Sbjct: 744 LLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNA-FSPLHCAV 802
Query: 284 IAGNLDLAEVI 294
I N AE++
Sbjct: 803 INDNEGAAEML 813
Score = 45.2 bits (102), Expect = 6e-04
Identities = 50/207 (24%), Positives = 86/207 (41%), Gaps = 17/207 (8%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAV---EKNSLEAVKT-- 160
E G TPL AA + K L L+ A R + G A+H + + L+ + +
Sbjct: 475 ERGCTPLHYAATSDTDGKCLEYLLRNDANPGIRDKQGYNAVHYSAAYGHRLCLQLIASET 534
Query: 161 ----LLELGASPNYKDGKG---LTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEV 213
L+E + D ++PL+L+ + L E L+ + + G +
Sbjct: 535 PLDVLMETSGTDMLSDSDNRATISPLHLAAYHGHHQAL-EVLVQSLLDLDVRNSSGRTPL 593
Query: 214 HQACRNGLVQHVDHLLFYGADMNARN-ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
A G V+ VD L+ GA + ++ TP+H A N C R L+ + A++
Sbjct: 594 DLAAFKGHVECVDVLINQGASILVKDYILKRTPIHAAATNGHSECLRLLIGNAEPQNAVD 653
Query: 273 FAN---QTPYQVAVIAGNLDLAEVIKN 296
+ QTP ++V+ G+ D + N
Sbjct: 654 IQDGNGQTPLMLSVLNGHTDCVYSLLN 680
Score = 33.5 bits (73), Expect = 1.9
Identities = 23/86 (26%), Positives = 36/86 (41%)
Query: 215 QACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFA 274
QA NG V L+F D+N ++ TPLH A L+ G A +
Sbjct: 20 QAIFNGDPDEVRALIFKKEDVNFQDNEKRTPLHAAAYLGDAEIIELLILSGARVNAKDSK 79
Query: 275 NQTPYQVAVIAGNLDLAEVIKNYKSD 300
TP AV + + + +V+ + +D
Sbjct: 80 WLTPLHRAVASCSEEAVQVLLKHSAD 105
Score = 31.9 bits (69), Expect = 5.7
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 4/107 (3%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
TG+TPL +AA + + + + A L + +TA+H A K + +LE
Sbjct: 861 TGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKIT 920
Query: 167 SPNYKDGKGL---TPLYLSVTNKTDPLLCETLLHDHATIGATDLQGW 210
N + TPL+++ N ++ + LL A++ A D G+
Sbjct: 921 DRNLINATNAALQTPLHVAARNGL-TMVVQELLGKGASVLAVDENGY 966
>BC063622-1|AAH63622.1| 367|Homo sapiens ANKRD44 protein protein.
Length = 367
Score = 78.2 bits (184), Expect = 7e-14
Identities = 58/192 (30%), Positives = 92/192 (47%), Gaps = 8/192 (4%)
Query: 109 ETPLTIAAGLKSP--AKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
+TPL +AA K+ A+++I L++ + D R G TA+H A +E V LL GA
Sbjct: 108 QTPLHVAAANKAVKCAEVIIPLLSSVNVSD---RGGRTALHHAALNGHVEMVNLLLAKGA 164
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVD 226
+ N D K L+ + ++ L++ A + D +G+ +H A NG + V
Sbjct: 165 NINAFDKKDRRALHWAAYMGHLDVVA-LLINHGAEVTCKDKKGYTPLHAAASNGQINVVK 223
Query: 227 HLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA- 285
HLL G +++ N GNT LH+ N QD+ +L+ G + N TP A +
Sbjct: 224 HLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAAST 283
Query: 286 -GNLDLAEVIKN 296
G L L ++ N
Sbjct: 284 HGALCLELLVNN 295
Score = 76.2 bits (179), Expect = 3e-13
Identities = 54/187 (28%), Positives = 89/187 (47%), Gaps = 2/187 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL +AA L A+I+ L+ GA ++ + T +HRAV S EAV+ L++ A N
Sbjct: 43 TPLHVAAFL-GDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVN 101
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
+D TPL+++ NK E ++ +++ +D G +H A NG V+ V+ LL
Sbjct: 102 ARDKNWQTPLHVAAANKA-VKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLL 160
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
GA++NA + LH A L+ G + + TP A G ++
Sbjct: 161 AKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQIN 220
Query: 290 LAEVIKN 296
+ + + N
Sbjct: 221 VVKHLLN 227
Score = 69.3 bits (162), Expect = 3e-11
Identities = 51/194 (26%), Positives = 83/194 (42%), Gaps = 5/194 (2%)
Query: 76 RRFLEHVTH-GQIDKITKACAKGLDPNFHCQET-GETPLTIAAGLKSPAKILIALVNGGA 133
RR L + G +D + G + C++ G TPL AA ++ L+N G
Sbjct: 174 RRALHWAAYMGHLDVVALLINHGAEVT--CKDKKGYTPLHAAAS-NGQINVVKHLLNLGV 230
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
+D G+TA+H A V L++ GA+ N + G TPL+ + + L E
Sbjct: 231 EIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLE 290
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
L+++ A + G +H +G L+ G +++ + GNTPLHV A
Sbjct: 291 LLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYG 350
Query: 254 QDSCARQLLFRGCD 267
+ L+ G D
Sbjct: 351 HELLINTLITSGAD 364
Score = 66.5 bits (155), Expect = 2e-10
Identities = 53/215 (24%), Positives = 101/215 (46%), Gaps = 7/215 (3%)
Query: 76 RRFLEHVT-HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGAL 134
R L H +G ++ + AKG N + + + A ++ L+N GA
Sbjct: 141 RTALHHAALNGHVEMVNLLLAKGA--NINAFDKKDRRALHWAAYMGHLDVVALLINHGAE 198
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+ + + G T +H A + VK LL LG + + G T L+++ N D ++ E
Sbjct: 199 VTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNE- 257
Query: 195 LLHDHATIGATDLQGWQEVH--QACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVN 252
L+ A + + G+ +H A +G + ++ L+ GAD+N ++ G +PLH+ AV+
Sbjct: 258 LIDYGANVNQPNNNGFTPLHFAAASTHGALC-LELLVNNGADVNIQSKDGKSPLHMTAVH 316
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
+ + ++ L+ G + + ++ TP VA G+
Sbjct: 317 GRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGH 351
Score = 63.7 bits (148), Expect = 2e-09
Identities = 48/195 (24%), Positives = 92/195 (47%), Gaps = 4/195 (2%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
T + PL A P +I + L++ ++ + T +H A E ++ L+ GA
Sbjct: 7 TDQPPLVQAIFSGDPEEIRM-LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGA 65
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQE-VHQACRNGLVQHV 225
N KD LTPL+ +V ++++ + + L+ A + A D + WQ +H A N V+
Sbjct: 66 RVNAKDNMWLTPLHRAVASRSEEAV-QVLIKHSADVNARD-KNWQTPLHVAAANKAVKCA 123
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+ ++ + +N + G T LH A+N LL +G + A + ++ A
Sbjct: 124 EVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYM 183
Query: 286 GNLDLAEVIKNYKSD 300
G+LD+ ++ N+ ++
Sbjct: 184 GHLDVVALLINHGAE 198
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/120 (27%), Positives = 50/120 (41%)
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
DP L+H + D + +H A G + ++ L+ GA +NA++ TPLH
Sbjct: 20 DPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLH 79
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRG 307
+ + + L+ D A + QTP VA + AEVI S V RG
Sbjct: 80 RAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRG 139
>BC050586-1|AAH50586.2| 306|Homo sapiens ANKRD44 protein protein.
Length = 306
Score = 78.2 bits (184), Expect = 7e-14
Identities = 58/192 (30%), Positives = 92/192 (47%), Gaps = 8/192 (4%)
Query: 109 ETPLTIAAGLKSP--AKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
+TPL +AA K+ A+++I L++ + D R G TA+H A +E V LL GA
Sbjct: 47 QTPLHVAAANKAVKCAEVIIPLLSSVNVSD---RGGRTALHHAALNGHVEMVNLLLAKGA 103
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVD 226
+ N D K L+ + ++ L++ A + D +G+ +H A NG + V
Sbjct: 104 NINAFDKKDRRALHWAAYMGHLDVVA-LLINHGAEVTCKDKKGYTPLHAAASNGQINVVK 162
Query: 227 HLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA- 285
HLL G +++ N GNT LH+ N QD+ +L+ G + N TP A +
Sbjct: 163 HLLNLGVEIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAAST 222
Query: 286 -GNLDLAEVIKN 296
G L L ++ N
Sbjct: 223 HGALCLELLVNN 234
Score = 69.3 bits (162), Expect = 3e-11
Identities = 51/194 (26%), Positives = 83/194 (42%), Gaps = 5/194 (2%)
Query: 76 RRFLEHVTH-GQIDKITKACAKGLDPNFHCQET-GETPLTIAAGLKSPAKILIALVNGGA 133
RR L + G +D + G + C++ G TPL AA ++ L+N G
Sbjct: 113 RRALHWAAYMGHLDVVALLINHGAEVT--CKDKKGYTPLHAAAS-NGQINVVKHLLNLGV 169
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
+D G+TA+H A V L++ GA+ N + G TPL+ + + L E
Sbjct: 170 EIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLE 229
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
L+++ A + G +H +G L+ G +++ + GNTPLHV A
Sbjct: 230 LLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYG 289
Query: 254 QDSCARQLLFRGCD 267
+ L+ G D
Sbjct: 290 HELLINTLITSGAD 303
Score = 66.5 bits (155), Expect = 2e-10
Identities = 53/215 (24%), Positives = 101/215 (46%), Gaps = 7/215 (3%)
Query: 76 RRFLEHVT-HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGAL 134
R L H +G ++ + AKG N + + + A ++ L+N GA
Sbjct: 80 RTALHHAALNGHVEMVNLLLAKGA--NINAFDKKDRRALHWAAYMGHLDVVALLINHGAE 137
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+ + + G T +H A + VK LL LG + + G T L+++ N D ++ E
Sbjct: 138 VTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNGQDAVVNE- 196
Query: 195 LLHDHATIGATDLQGWQEVH--QACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVN 252
L+ A + + G+ +H A +G + ++ L+ GAD+N ++ G +PLH+ AV+
Sbjct: 197 LIDYGANVNQPNNNGFTPLHFAAASTHGALC-LELLVNNGADVNIQSKDGKSPLHMTAVH 255
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
+ + ++ L+ G + + ++ TP VA G+
Sbjct: 256 GRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYGH 290
Score = 66.1 bits (154), Expect = 3e-10
Identities = 45/165 (27%), Positives = 76/165 (46%), Gaps = 1/165 (0%)
Query: 132 GALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLL 191
GA ++ + T +HRAV S EAV+ L++ A N +D TPL+++ NK
Sbjct: 3 GARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKA-VKC 61
Query: 192 CETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAV 251
E ++ +++ +D G +H A NG V+ V+ LL GA++NA + LH A
Sbjct: 62 AEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAY 121
Query: 252 NAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
L+ G + + TP A G +++ + + N
Sbjct: 122 MGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLN 166
Score = 56.0 bits (129), Expect = 3e-07
Identities = 36/137 (26%), Positives = 68/137 (49%), Gaps = 3/137 (2%)
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQE-VHQACRNGLVQ 223
GA N KD LTPL+ +V ++++ + + L+ A + A D + WQ +H A N V+
Sbjct: 3 GARVNAKDNMWLTPLHRAVASRSEEAV-QVLIKHSADVNARD-KNWQTPLHVAAANKAVK 60
Query: 224 HVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ ++ + +N + G T LH A+N LL +G + A + ++ A
Sbjct: 61 CAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAA 120
Query: 284 IAGNLDLAEVIKNYKSD 300
G+LD+ ++ N+ ++
Sbjct: 121 YMGHLDVVALLINHGAE 137
Score = 33.1 bits (72), Expect = 2.5
Identities = 24/76 (31%), Positives = 33/76 (43%)
Query: 232 GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
GA +NA++ TPLH + + + L+ D A + QTP VA + A
Sbjct: 3 GARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCA 62
Query: 292 EVIKNYKSDEIVPFRG 307
EVI S V RG
Sbjct: 63 EVIIPLLSSVNVSDRG 78
>BC101273-1|AAI01274.1| 399|Homo sapiens ANKDD1A protein protein.
Length = 399
Score = 77.8 bits (183), Expect = 9e-14
Identities = 56/184 (30%), Positives = 88/184 (47%), Gaps = 3/184 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HGQ+D + G D N +E G T L +AAG + +L LV+ G L+ + +G
Sbjct: 78 HGQLDALDFLVGSGCDHNVKDKE-GNTALHLAAG-RGHMAVLQRLVDIGLDLEEQNAEGL 135
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
TA+H A + + V+ LL G++ N K L+ L+ + + ++ + L+H
Sbjct: 136 TALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDV-SRVLIHAGGCAN 194
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D QG +H A R+ V L+ +D+NA + TPLH+ A +A A LL
Sbjct: 195 VVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLAAEHAWQDIADMLLI 254
Query: 264 RGCD 267
G D
Sbjct: 255 AGVD 258
Score = 61.7 bits (143), Expect = 6e-09
Identities = 46/175 (26%), Positives = 81/175 (46%), Gaps = 5/175 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE--LGASPNYKDGKGLTPLY 180
+IL LVN GA + ++DG T +H A +K + + ++E + ++ D G T +
Sbjct: 14 RILQILVNSGAKIHCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFH 73
Query: 181 LSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN 239
+ + + D L + L+ D +G +H A G + + L+ G D+ +N
Sbjct: 74 RAAEHGQLDAL--DFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLVDIGLDLEEQN 131
Query: 240 ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
A G T LH A + C + LL G AL N + A ++G+ D++ V+
Sbjct: 132 AEGLTALHSAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVL 186
Score = 60.5 bits (140), Expect = 1e-08
Identities = 49/200 (24%), Positives = 83/200 (41%), Gaps = 3/200 (1%)
Query: 103 HCQETGETPLTIAAGLKSPAKILIALVNG--GALLDYRTRDGSTAMHRAVEKNSLEAVKT 160
HC+ L A K +L ++ LD+ + G TA HRA E L+A+
Sbjct: 27 HCESKDGLTLLHCAAQKGHVPVLAFIMEDLEDVALDHVDKLGRTAFHRAAEHGQLDALDF 86
Query: 161 LLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG 220
L+ G N KD +G T L+L+ + + + L+ + + +G +H A
Sbjct: 87 LVGSGCDHNVKDKEGNTALHLAA-GRGHMAVLQRLVDIGLDLEEQNAEGLTALHSAAGGS 145
Query: 221 LVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQ 280
V LL G+ +NA + LH A++ + +R L+ G ++ +P
Sbjct: 146 HPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSEDVSRVLIHAGGCANVVDHQGASPLH 205
Query: 281 VAVIAGNLDLAEVIKNYKSD 300
+AV L ++ N SD
Sbjct: 206 LAVRHNFPALVRLLINSDSD 225
Score = 59.7 bits (138), Expect = 2e-08
Identities = 46/192 (23%), Positives = 85/192 (44%), Gaps = 2/192 (1%)
Query: 103 HCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL 162
H + G T AA L LV G + + ++G+TA+H A + + ++ L+
Sbjct: 63 HVDKLGRTAFHRAAE-HGQLDALDFLVGSGCDHNVKDKEGNTALHLAAGRGHMAVLQRLV 121
Query: 163 ELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLV 222
++G ++ +GLT L+ S + P + LL +T+ A + +H A +G
Sbjct: 122 DIGLDLEEQNAEGLTALH-SAAGGSHPDCVQLLLRAGSTVNALTQKNLSCLHYAALSGSE 180
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
L+ G N + G +PLH+ + + R L+ D A++ QTP +A
Sbjct: 181 DVSRVLIHAGGCANVVDHQGASPLHLAVRHNFPALVRLLINSDSDVNAVDNRQQTPLHLA 240
Query: 283 VIAGNLDLAEVI 294
D+A+++
Sbjct: 241 AEHAWQDIADML 252
>BC032354-1|AAH32354.1| 587|Homo sapiens ankyrin repeat and SOCS
box-containing 2 protein.
Length = 587
Score = 77.4 bits (182), Expect = 1e-13
Identities = 78/298 (26%), Positives = 129/298 (43%), Gaps = 18/298 (6%)
Query: 24 KAGKFLDEERRLGDYPFNGPVGYLE---LKYKRRVYKMLKLDEKTLKALHSRANLRRFLE 80
K GK L E + G P + Y + LK +R Y +D++TL+ +L
Sbjct: 78 KEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGT-IDQRTLQE-----ETAVYLA 131
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
G +D + G +P+ ++ ETPL A K+ + I LV A ++R
Sbjct: 132 -TCRGHLDCLLSLLQAGAEPDIS-NKSRETPLYKACERKNAEAVKI-LVQHNADTNHRCN 188
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
G TA+H +V +N LE ++ L+ GA K+ G+TPL+++ + L L A
Sbjct: 189 RGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEAL-RFLAKYGA 247
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
I +++AC+N + V+ LL GAD N N G PLH+ + Q
Sbjct: 248 DINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIV-Q 306
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRGPPR---YNPRR 315
+L + + + +P +A + ++ E + + + D P P R Y RR
Sbjct: 307 MLLPVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPL-APERARLYEDRR 363
Score = 36.7 bits (81), Expect = 0.20
Identities = 24/124 (19%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL-LFYGADMN 236
PL ++ + + L +T++ + + + +GW +H+A G V + L Y ++
Sbjct: 60 PLIKAIKDGDEEAL-KTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTID 118
Query: 237 ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
R T +++ C LL G + + N + +TP A N + +++
Sbjct: 119 QRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQ 178
Query: 297 YKSD 300
+ +D
Sbjct: 179 HNAD 182
>AL159174-1|CAI39609.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 77.4 bits (182), Expect = 1e-13
Identities = 51/182 (28%), Positives = 85/182 (46%), Gaps = 4/182 (2%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A K + ++ L+N GA + T+ G T +H A K L V+ LL+ G + +D
Sbjct: 15 LVAAYKGQTENVVQLINKGARVAV-TKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDD 73
Query: 174 KGLTPLY-LSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T L+ +V T+ + L+H+ + D G +H+A +G Q L+ G
Sbjct: 74 GDQTALHRATVVGNTE--IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAG 131
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAE 292
A++ A+N +GNT LH+ N+ R LL G + N A T VA +L +
Sbjct: 132 ANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIR 191
Query: 293 VI 294
++
Sbjct: 192 LL 193
Score = 72.1 bits (169), Expect = 4e-12
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 1/187 (0%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL 164
Q+ G+ A + +I+ AL++ G LD + +DG+TA+H A ++ K L++
Sbjct: 71 QDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKA 130
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
GA+ K+ G T L+L+ N + LL + + G +H A R +
Sbjct: 131 GANVLAKNKAGNTALHLACQN-SHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSI 189
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
+ LL ++ +N +G+T LHV A A+ LL G D +N A QTP + A
Sbjct: 190 IRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARY 249
Query: 285 AGNLDLA 291
N ++A
Sbjct: 250 HNNPEVA 256
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/227 (26%), Positives = 97/227 (42%), Gaps = 4/227 (1%)
Query: 77 RFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLD 136
R L GQ + + + KG + G TPL +AA K ++ L+ G LD
Sbjct: 13 RLLVAAYKGQTENVVQLINKGA--RVAVTKHGRTPLHLAAN-KGHLPVVQILLKAGCDLD 69
Query: 137 YRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLL 196
+ TA+HRA + E + L+ G + + +D G T L+ + + + L+
Sbjct: 70 VQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQS-AKLLI 128
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDS 256
A + A + G +H AC+N Q LL G+ + +N +G+T LHV A S
Sbjct: 129 KAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLS 188
Query: 257 CARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIV 303
R LL C N A T VA + +A+++ +D +
Sbjct: 189 IIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTI 235
>AL096678-2|CAI42280.1| 692|Homo sapiens ankyrin repeat domain 6
protein.
Length = 692
Score = 77.4 bits (182), Expect = 1e-13
Identities = 51/182 (28%), Positives = 85/182 (46%), Gaps = 4/182 (2%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A K + ++ L+N GA + T+ G T +H A K L V+ LL+ G + +D
Sbjct: 15 LVAAYKGQTENVVQLINKGARVAV-TKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDD 73
Query: 174 KGLTPLY-LSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T L+ +V T+ + L+H+ + D G +H+A +G Q L+ G
Sbjct: 74 GDQTALHRATVVGNTE--IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAG 131
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAE 292
A++ A+N +GNT LH+ N+ R LL G + N A T VA +L +
Sbjct: 132 ANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIR 191
Query: 293 VI 294
++
Sbjct: 192 LL 193
Score = 72.1 bits (169), Expect = 4e-12
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 1/187 (0%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL 164
Q+ G+ A + +I+ AL++ G LD + +DG+TA+H A ++ K L++
Sbjct: 71 QDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKA 130
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
GA+ K+ G T L+L+ N + LL + + G +H A R +
Sbjct: 131 GANVLAKNKAGNTALHLACQN-SHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSI 189
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
+ LL ++ +N +G+T LHV A A+ LL G D +N A QTP + A
Sbjct: 190 IRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARY 249
Query: 285 AGNLDLA 291
N ++A
Sbjct: 250 HNNPEVA 256
Score = 70.9 bits (166), Expect = 1e-11
Identities = 60/227 (26%), Positives = 97/227 (42%), Gaps = 4/227 (1%)
Query: 77 RFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLD 136
R L GQ + + + KG + G TPL +AA K ++ L+ G LD
Sbjct: 13 RLLVAAYKGQTENVVQLINKGA--RVAVTKHGRTPLHLAAN-KGHLPVVQILLKAGCDLD 69
Query: 137 YRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLL 196
+ TA+HRA + E + L+ G + + +D G T L+ + + + L+
Sbjct: 70 VQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQS-AKLLI 128
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDS 256
A + A + G +H AC+N Q LL G+ + +N +G+T LHV A S
Sbjct: 129 KAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLS 188
Query: 257 CARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIV 303
R LL C N A T VA + +A+++ +D +
Sbjct: 189 IIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTI 235
>AK127855-1|BAC87163.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ45958 fis, clone PLACE7011559, highly similar
to Death-associated protein kinase 1 (EC 2.7.1.-). ).
Length = 337
Score = 77.4 bits (182), Expect = 1e-13
Identities = 49/161 (30%), Positives = 77/161 (47%), Gaps = 3/161 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG C G + N +E GETPL + A + I+ L GA L+ +DG
Sbjct: 42 HGHYSVAKALCEAGCNVNIKNRE-GETPL-LTASARGYHDIVECLAEHGADLNACDKDGH 99
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
A+H AV + +E +KTLL G +Y+D G TPL+++ + P++ L + +
Sbjct: 100 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV-ALCEANCNLD 158
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
++ G +H A NG++ V +L GA + A G T
Sbjct: 159 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 199
Score = 74.5 bits (175), Expect = 8e-13
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRD 141
+G D C+ G +PN +E ETPL AA G S AK AL G ++ + R+
Sbjct: 9 YGHADVAQLLCSFGSNPNIQDKEE-ETPLHCAAWHGHYSVAK---ALCEAGCNVNIKNRE 64
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T + A + + V+ L E GA N D G L+L+V + + +TLL
Sbjct: 65 GETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAV-RRCQMEVIKTLLSQGCF 123
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ D G +H AC++G + V L +++ N G TPLH+ A N R L
Sbjct: 124 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 183
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G EAL +T +A + +A ++ + D
Sbjct: 184 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKD 222
Score = 53.2 bits (122), Expect = 2e-06
Identities = 36/146 (24%), Positives = 64/146 (43%), Gaps = 1/146 (0%)
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A + + L G++PN +D + TPL+ + + + + L +
Sbjct: 2 ALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWH-GHYSVAKALCEAGCNVNI 60
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
+ +G + A G V+ L +GAD+NA + G+ LH+ Q + LL +
Sbjct: 61 KNREGETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAVRRCQMEVIKTLLSQ 120
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDL 290
GC + + TP VA GN+ +
Sbjct: 121 GCFVDYQDRHGNTPLHVACKDGNMPI 146
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/88 (28%), Positives = 39/88 (44%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A R G L +G++ N ++ TPLH A + S A+ L GC+ N
Sbjct: 3 LHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGHYSVAKALCEAGCNVNIKN 62
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+TP A G D+ E + + +D
Sbjct: 63 REGETPLLTASARGYHDIVECLAEHGAD 90
>AJ251238-1|CAC17765.1| 587|Homo sapiens hypothetical protein
protein.
Length = 587
Score = 77.4 bits (182), Expect = 1e-13
Identities = 78/298 (26%), Positives = 129/298 (43%), Gaps = 18/298 (6%)
Query: 24 KAGKFLDEERRLGDYPFNGPVGYLE---LKYKRRVYKMLKLDEKTLKALHSRANLRRFLE 80
K GK L E + G P + Y + LK +R Y +D++TL+ +L
Sbjct: 78 KEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGT-IDQRTLQE-----ETAVYLA 131
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
G +D + G +P+ ++ ETPL A K+ + I LV A ++R
Sbjct: 132 -TCRGHLDCLLSLLQAGAEPDIS-NKSRETPLYKACERKNAEAVKI-LVQHNADTNHRCN 188
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
G TA+H +V +N LE ++ L+ GA K+ G+TPL+++ + L L A
Sbjct: 189 RGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEAL-RFLAKYGA 247
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
I +++AC+N + V+ LL GAD N N G PLH+ + Q
Sbjct: 248 DINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIV-Q 306
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRGPPR---YNPRR 315
+L + + + +P +A + ++ E + + + D P P R Y RR
Sbjct: 307 MLLPVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPL-APERARLYEDRR 363
Score = 36.7 bits (81), Expect = 0.20
Identities = 24/124 (19%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL-LFYGADMN 236
PL ++ + + L +T++ + + + +GW +H+A G V + L Y ++
Sbjct: 60 PLIKAIKDGDEEAL-KTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTID 118
Query: 237 ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
R T +++ C LL G + + N + +TP A N + +++
Sbjct: 119 QRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQ 178
Query: 297 YKSD 300
+ +D
Sbjct: 179 HNAD 182
>AB056723-1|BAB64532.1| 587|Homo sapiens ankyrin repeat-conteining
protein with a SOCS box-2 protein.
Length = 587
Score = 77.4 bits (182), Expect = 1e-13
Identities = 78/298 (26%), Positives = 129/298 (43%), Gaps = 18/298 (6%)
Query: 24 KAGKFLDEERRLGDYPFNGPVGYLE---LKYKRRVYKMLKLDEKTLKALHSRANLRRFLE 80
K GK L E + G P + Y + LK +R Y +D++TL+ +L
Sbjct: 78 KEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGT-IDQRTLQE-----ETAVYLA 131
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
G +D + G +P+ ++ ETPL A K+ + I LV A ++R
Sbjct: 132 -TCRGHLDCLLSLLQAGAEPDIS-NKSRETPLYKACERKNAEAVKI-LVQHNADTNHRCN 188
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
G TA+H +V +N LE ++ L+ GA K+ G+TPL+++ + L L A
Sbjct: 189 RGWTALHESVSRNDLEVMQILVSGGAKVESKNAYGITPLFVAAQSGQLEAL-RFLAKYGA 247
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
I +++AC+N + V+ LL GAD N N G PLH+ + Q
Sbjct: 248 DINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIV-Q 306
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRGPPR---YNPRR 315
+L + + + +P +A + ++ E + + + D P P R Y RR
Sbjct: 307 MLLPVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPL-APERARLYEDRR 363
Score = 36.7 bits (81), Expect = 0.20
Identities = 24/124 (19%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL-LFYGADMN 236
PL ++ + + L +T++ + + + +GW +H+A G V + L Y ++
Sbjct: 60 PLIKAIKDGDEEAL-KTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTID 118
Query: 237 ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
R T +++ C LL G + + N + +TP A N + +++
Sbjct: 119 QRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQ 178
Query: 297 YKSD 300
+ +D
Sbjct: 179 HNAD 182
>X76104-1|CAA53712.1| 1431|Homo sapiens DAP-kinase protein.
Length = 1431
Score = 77.0 bits (181), Expect = 2e-13
Identities = 49/161 (30%), Positives = 77/161 (47%), Gaps = 3/161 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG C G + N +E GETPL + A + I+ L GA L+ +DG
Sbjct: 489 HGYYSVAKALCEAGCNVNIKNRE-GETPL-LTASARGYHDIVECLAEHGADLNACDKDGH 546
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
A+H AV + +E +KTLL G +Y+D G TPL+++ + P++ L + +
Sbjct: 547 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV-ALCEANCNLD 605
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
++ G +H A NG++ V +L GA + A G T
Sbjct: 606 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 646
Score = 68.9 bits (161), Expect = 4e-11
Identities = 61/219 (27%), Positives = 92/219 (42%), Gaps = 6/219 (2%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRD 141
+G D CA + ETPL AA G S AK AL G ++ + R+
Sbjct: 455 YGHADVAQVTCAASAQIPISRTKEEETPLHCAAWHGYYSVAK---ALCEAGCNVNIKNRE 511
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T + A + + V+ L E GA N D G L+L+V + + +TLL
Sbjct: 512 GETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAV-RRCQMEVIKTLLSQGCF 570
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ D G +H AC++G + V L +++ N G TPLH+ A N R L
Sbjct: 571 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 630
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G EAL +T +A + +A ++ + D
Sbjct: 631 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKD 669
Score = 68.1 bits (159), Expect = 7e-11
Identities = 54/211 (25%), Positives = 89/211 (42%), Gaps = 2/211 (0%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG +D + K ++ P ++GE L +AA + + RT++
Sbjct: 422 HGHVDTL-KFLSENKCPLDVKDKSGEMALHVAARYGHADVAQVTCAASAQIPISRTKEEE 480
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A K L E G + N K+ +G TPL L+ + + + E L A +
Sbjct: 481 TPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPL-LTASARGYHDIVECLAEHGADLN 539
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
A D G +H A R ++ + LL G ++ ++ GNTPLHV + L
Sbjct: 540 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 599
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
C+ + N +TP +A G LD+ +
Sbjct: 600 ANCNLDISNKYGRTPLHLAANNGILDVVRYL 630
>DQ436495-1|ABD96827.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 77.0 bits (181), Expect = 2e-13
Identities = 49/161 (30%), Positives = 77/161 (47%), Gaps = 3/161 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG C G + N +E GETPL + A + I+ L GA L+ +DG
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNRE-GETPL-LTASARGYHDIVECLAEHGADLNACDKDGH 545
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
A+H AV + +E +KTLL G +Y+D G TPL+++ + P++ L + +
Sbjct: 546 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV-ALCEANCNLD 604
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
++ G +H A NG++ V +L GA + A G T
Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 645
Score = 75.4 bits (177), Expect = 5e-13
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRD 141
+G D C+ G +PN +E ETPL AA G S AK AL G ++ + R+
Sbjct: 455 YGHADVAQLLCSFGSNPNIQDKEE-ETPLHCAAWHGYYSVAK---ALCEAGCNVNIKNRE 510
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T + A + + V+ L E GA N D G L+L+V + + +TLL
Sbjct: 511 GETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAV-RRCQMEVIKTLLSQGCF 569
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ D G +H AC++G + V L +++ N G TPLH+ A N R L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G EAL +T +A + +A ++ + D
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKD 668
Score = 67.3 bits (157), Expect = 1e-10
Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 3/211 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG +D + K ++ P ++GE L +AA A + L + G+ + + ++
Sbjct: 422 HGHVDTL-KFLSENKCPLDVKDKSGEMALHVAARY-GHADVAQLLCSFGSNPNIQDKEEE 479
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A K L E G + N K+ +G TPL L+ + + + E L A +
Sbjct: 480 TPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPL-LTASARGYHDIVECLAEHGADLN 538
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
A D G +H A R ++ + LL G ++ ++ GNTPLHV + L
Sbjct: 539 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
C+ + N +TP +A G LD+ +
Sbjct: 599 ANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 1/161 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+ G+ + A +++ ++ L++ G+ + +D G +Y + + L + L +
Sbjct: 377 KHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL-KFLSENK 435
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
+ D G +H A R G L +G++ N ++ TPLH A + S A+
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAK 495
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L GC+ N +TP A G D+ E + + +D
Sbjct: 496 ALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 536
>BC113660-1|AAI13661.1| 1430|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1430
Score = 77.0 bits (181), Expect = 2e-13
Identities = 49/161 (30%), Positives = 77/161 (47%), Gaps = 3/161 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG C G + N +E GETPL + A + I+ L GA L+ +DG
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNRE-GETPL-LTASARGYHDIVECLAEHGADLNACDKDGH 545
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
A+H AV + +E +KTLL G +Y+D G TPL+++ + P++ L + +
Sbjct: 546 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV-ALCEANCNLD 604
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
++ G +H A NG++ V +L GA + A G T
Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 645
Score = 75.4 bits (177), Expect = 5e-13
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRD 141
+G D C+ G +PN +E ETPL AA G S AK AL G ++ + R+
Sbjct: 455 YGHADVAQLLCSFGSNPNIQDKEE-ETPLHCAAWHGYYSVAK---ALCEAGCNVNIKNRE 510
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T + A + + V+ L E GA N D G L+L+V + + +TLL
Sbjct: 511 GETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAV-RRCQMEVIKTLLSQGCF 569
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ D G +H AC++G + V L +++ N G TPLH+ A N R L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G EAL +T +A + +A ++ + D
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKD 668
Score = 67.3 bits (157), Expect = 1e-10
Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 3/211 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG +D + K ++ P ++GE L +AA A + L + G+ + + ++
Sbjct: 422 HGHVDTL-KFLSENKCPLDVKDKSGEMALHVAARY-GHADVAQLLCSFGSNPNIQDKEEE 479
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A K L E G + N K+ +G TPL L+ + + + E L A +
Sbjct: 480 TPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPL-LTASARGYHDIVECLAEHGADLN 538
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
A D G +H A R ++ + LL G ++ ++ GNTPLHV + L
Sbjct: 539 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
C+ + N +TP +A G LD+ +
Sbjct: 599 ANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 1/161 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+ G+ + A +++ ++ L++ G+ + +D G +Y + + L + L +
Sbjct: 377 KHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL-KFLSENK 435
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
+ D G +H A R G L +G++ N ++ TPLH A + S A+
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAK 495
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L GC+ N +TP A G D+ E + + +D
Sbjct: 496 ALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 536
>BC110618-1|AAI10619.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 77.0 bits (181), Expect = 2e-13
Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D G++ +H AVE E K LL A+PN + +G TPL+++V + ++ E
Sbjct: 431 VDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVV-EL 489
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL ++ A D W +H A +NG LL A +N + G TP+HV + Q
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 549
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
++ R LL RG D P A G+L + +++
Sbjct: 550 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 589
Score = 64.5 bits (150), Expect = 9e-10
Identities = 46/168 (27%), Positives = 72/168 (42%), Gaps = 2/168 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
+G T MH A + V+ LL G + + PL+ + P++
Sbjct: 536 EGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
++ A L G +H A + G + L+ +D+N + TPLHV A S AR
Sbjct: 596 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARL 655
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRGP 308
LL RG KEA+ T +A G+L +++ K+D + RGP
Sbjct: 656 LLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLA--RGP 701
Score = 56.8 bits (131), Expect = 2e-07
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 4/180 (2%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HGQ + + +G+D + ++ PL AA + + G ++ +T DG
Sbjct: 547 HGQENIVRILLRRGVDVSLQGKDAW-LPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGR 605
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLLHDHATI 202
T +H A ++ + L++L + N TPL+++ T T LLH A
Sbjct: 606 TPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTST--ARLLLHRGAGK 663
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
A G+ +H A RNG + V L+ AD+ AR T LH+ A + +L+
Sbjct: 664 EAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV 723
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/186 (25%), Positives = 75/186 (40%), Gaps = 3/186 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL-GA 166
G TP+ +A I+ L+ G + + +D +H A + L VK L + G
Sbjct: 537 GRTPMHVACQ-HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVD 226
S N + G TPL+L+ + + L+ + + L +H A G
Sbjct: 596 SVNAQTLDGRTPLHLAA-QRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 654
Query: 227 HLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
LL GA A + G T LH+ A N + + L+ D A NQT +A G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 287 NLDLAE 292
+ ++ E
Sbjct: 715 HSEVVE 720
>BC110617-1|AAI10618.1| 784|Homo sapiens receptor-interacting
serine-threonine kinase 4 protein.
Length = 784
Score = 77.0 bits (181), Expect = 2e-13
Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D G++ +H AVE E K LL A+PN + +G TPL+++V + ++ E
Sbjct: 431 VDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVV-EL 489
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL ++ A D W +H A +NG LL A +N + G TP+HV + Q
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 549
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
++ R LL RG D P A G+L + +++
Sbjct: 550 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 589
Score = 64.5 bits (150), Expect = 9e-10
Identities = 46/168 (27%), Positives = 72/168 (42%), Gaps = 2/168 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
+G T MH A + V+ LL G + + PL+ + P++
Sbjct: 536 EGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
++ A L G +H A + G + L+ +D+N + TPLHV A S AR
Sbjct: 596 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARL 655
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRGP 308
LL RG KEA+ T +A G+L +++ K+D + RGP
Sbjct: 656 LLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLA--RGP 701
Score = 56.8 bits (131), Expect = 2e-07
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 4/180 (2%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HGQ + + +G+D + ++ PL AA + + G ++ +T DG
Sbjct: 547 HGQENIVRILLRRGVDVSLQGKDAW-LPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGR 605
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLLHDHATI 202
T +H A ++ + L++L + N TPL+++ T T LLH A
Sbjct: 606 TPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTST--ARLLLHRGAGK 663
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
A G+ +H A RNG + V L+ AD+ AR T LH+ A + +L+
Sbjct: 664 EAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV 723
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/186 (25%), Positives = 75/186 (40%), Gaps = 3/186 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL-GA 166
G TP+ +A I+ L+ G + + +D +H A + L VK L + G
Sbjct: 537 GRTPMHVACQ-HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVD 226
S N + G TPL+L+ + + L+ + + L +H A G
Sbjct: 596 SVNAQTLDGRTPLHLAA-QRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 654
Query: 227 HLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
LL GA A + G T LH+ A N + + L+ D A NQT +A G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 287 NLDLAE 292
+ ++ E
Sbjct: 715 HSEVVE 720
>BC042173-1|AAH42173.1| 722|Homo sapiens ankyrin repeat domain 6
protein.
Length = 722
Score = 77.0 bits (181), Expect = 2e-13
Identities = 51/182 (28%), Positives = 85/182 (46%), Gaps = 4/182 (2%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A K + ++ L+N GA + T+ G T +H A K L V+ LL+ G + +D
Sbjct: 15 LVAAYKGQTENVVQLINKGARVAV-TKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDD 73
Query: 174 KGLTPLY-LSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T L+ +V T+ + L+H+ + D G +H+A +G Q L+ G
Sbjct: 74 GDQTALHRATVVGNTE--IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAG 131
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAE 292
A++ A+N +GNT LH+ N+ R LL G + N A T VA +L +
Sbjct: 132 ANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIR 191
Query: 293 VI 294
++
Sbjct: 192 LL 193
Score = 72.9 bits (171), Expect = 2e-12
Identities = 59/213 (27%), Positives = 100/213 (46%), Gaps = 4/213 (1%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL 164
Q+ G+ A + +I+ AL++ G LD + +DG+TA+H A ++ K L++
Sbjct: 71 QDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKA 130
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
GA+ K+ G T L+L+ N + LL + + G +H A R +
Sbjct: 131 GANVLAKNKAGNTALHLACQN-SHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSI 189
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
+ LL ++ +N +G+T LHV A A+ LL G D +N A QTP + A
Sbjct: 190 IRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARY 249
Query: 285 AGNLDLAEVIKNYKSDEIVPF-RGPPRYNPRRR 316
N ++A ++ K+ +++ F RG R R
Sbjct: 250 HNNPEVALLLT--KAPQVLRFSRGRSLRKKRER 280
>AP001743-1|BAA95526.1| 832|Homo sapiens ANKRD3 protein.
Length = 832
Score = 77.0 bits (181), Expect = 2e-13
Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D G++ +H AVE E K LL A+PN + +G TPL+++V + ++ E
Sbjct: 479 VDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVV-EL 537
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL ++ A D W +H A +NG LL A +N + G TP+HV + Q
Sbjct: 538 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 597
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
++ R LL RG D P A G+L + +++
Sbjct: 598 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 637
Score = 64.9 bits (151), Expect = 7e-10
Identities = 46/168 (27%), Positives = 72/168 (42%), Gaps = 2/168 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
+G T MH A + V+ LL G + + PL+ + P++
Sbjct: 584 EGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 643
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
++ A L G +H A + G + L+ +D+N + TPLHV A S AR
Sbjct: 644 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARL 703
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRGP 308
LL RG KEA+ T +A G+L +++ K+D + RGP
Sbjct: 704 LLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLA--RGP 749
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 4/180 (2%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HGQ + + +G+D + ++ PL AA + + G ++ +T DG
Sbjct: 595 HGQENIVRILLRRGVDVSLQGKDAW-LPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGR 653
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLLHDHATI 202
T +H A ++ + L++L + N TPL+++ T T LLH A
Sbjct: 654 TPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTST--ARLLLHRGAGK 711
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
A G+ +H A RNG + V L+ AD+ AR T LH+ A + +L+
Sbjct: 712 EAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV 771
Score = 51.2 bits (117), Expect = 9e-06
Identities = 47/186 (25%), Positives = 75/186 (40%), Gaps = 3/186 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL-GA 166
G TP+ +A I+ L+ G + + +D +H A + L VK L + G
Sbjct: 585 GRTPMHVACQ-HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 643
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVD 226
S N + G TPL+L+ + + L+ + + L +H A G
Sbjct: 644 SVNAQTLDGRTPLHLAA-QRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 702
Query: 227 HLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
LL GA A + G T LH+ A N + + L+ D A NQT +A G
Sbjct: 703 LLLHRGAGKEAMTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 762
Query: 287 NLDLAE 292
+ ++ E
Sbjct: 763 HSEVVE 768
>AL591852-1|CAH71696.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.0 bits (181), Expect = 2e-13
Identities = 49/161 (30%), Positives = 77/161 (47%), Gaps = 3/161 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG C G + N +E GETPL + A + I+ L GA L+ +DG
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNRE-GETPL-LTASARGYHDIVECLAEHGADLNACDKDGH 545
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
A+H AV + +E +KTLL G +Y+D G TPL+++ + P++ L + +
Sbjct: 546 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV-ALCEANCNLD 604
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
++ G +H A NG++ V +L GA + A G T
Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 645
Score = 75.4 bits (177), Expect = 5e-13
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRD 141
+G D C+ G +PN +E ETPL AA G S AK AL G ++ + R+
Sbjct: 455 YGHADVAQLLCSFGSNPNIQDKEE-ETPLHCAAWHGYYSVAK---ALCEAGCNVNIKNRE 510
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T + A + + V+ L E GA N D G L+L+V + + +TLL
Sbjct: 511 GETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAV-RRCQMEVIKTLLSQGCF 569
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ D G +H AC++G + V L +++ N G TPLH+ A N R L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G EAL +T +A + +A ++ + D
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKD 668
Score = 67.3 bits (157), Expect = 1e-10
Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 3/211 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG +D + K ++ P ++GE L +AA A + L + G+ + + ++
Sbjct: 422 HGHVDTL-KFLSENKCPLDVKDKSGEMALHVAARY-GHADVAQLLCSFGSNPNIQDKEEE 479
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A K L E G + N K+ +G TPL L+ + + + E L A +
Sbjct: 480 TPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPL-LTASARGYHDIVECLAEHGADLN 538
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
A D G +H A R ++ + LL G ++ ++ GNTPLHV + L
Sbjct: 539 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
C+ + N +TP +A G LD+ +
Sbjct: 599 ANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 1/161 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+ G+ + A +++ ++ L++ G+ + +D G +Y + + L + L +
Sbjct: 377 KHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL-KFLSENK 435
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
+ D G +H A R G L +G++ N ++ TPLH A + S A+
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAK 495
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L GC+ N +TP A G D+ E + + +D
Sbjct: 496 ALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 536
>AL161787-1|CAH73544.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.0 bits (181), Expect = 2e-13
Identities = 49/161 (30%), Positives = 77/161 (47%), Gaps = 3/161 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG C G + N +E GETPL + A + I+ L GA L+ +DG
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNRE-GETPL-LTASARGYHDIVECLAEHGADLNACDKDGH 545
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
A+H AV + +E +KTLL G +Y+D G TPL+++ + P++ L + +
Sbjct: 546 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV-ALCEANCNLD 604
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
++ G +H A NG++ V +L GA + A G T
Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 645
Score = 75.4 bits (177), Expect = 5e-13
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRD 141
+G D C+ G +PN +E ETPL AA G S AK AL G ++ + R+
Sbjct: 455 YGHADVAQLLCSFGSNPNIQDKEE-ETPLHCAAWHGYYSVAK---ALCEAGCNVNIKNRE 510
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T + A + + V+ L E GA N D G L+L+V + + +TLL
Sbjct: 511 GETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAV-RRCQMEVIKTLLSQGCF 569
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ D G +H AC++G + V L +++ N G TPLH+ A N R L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G EAL +T +A + +A ++ + D
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKD 668
Score = 67.3 bits (157), Expect = 1e-10
Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 3/211 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG +D + K ++ P ++GE L +AA A + L + G+ + + ++
Sbjct: 422 HGHVDTL-KFLSENKCPLDVKDKSGEMALHVAARY-GHADVAQLLCSFGSNPNIQDKEEE 479
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A K L E G + N K+ +G TPL L+ + + + E L A +
Sbjct: 480 TPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPL-LTASARGYHDIVECLAEHGADLN 538
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
A D G +H A R ++ + LL G ++ ++ GNTPLHV + L
Sbjct: 539 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
C+ + N +TP +A G LD+ +
Sbjct: 599 ANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 1/161 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+ G+ + A +++ ++ L++ G+ + +D G +Y + + L + L +
Sbjct: 377 KHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL-KFLSENK 435
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
+ D G +H A R G L +G++ N ++ TPLH A + S A+
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAK 495
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L GC+ N +TP A G D+ E + + +D
Sbjct: 496 ALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 536
>AL160279-1|CAI16306.1| 1455|Homo sapiens death-associated protein
kinase 1 protein.
Length = 1455
Score = 77.0 bits (181), Expect = 2e-13
Identities = 49/161 (30%), Positives = 77/161 (47%), Gaps = 3/161 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG C G + N +E GETPL + A + I+ L GA L+ +DG
Sbjct: 488 HGYYSVAKALCEAGCNVNIKNRE-GETPL-LTASARGYHDIVECLAEHGADLNACDKDGH 545
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
A+H AV + +E +KTLL G +Y+D G TPL+++ + P++ L + +
Sbjct: 546 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV-ALCEANCNLD 604
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
++ G +H A NG++ V +L GA + A G T
Sbjct: 605 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 645
Score = 75.4 bits (177), Expect = 5e-13
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRD 141
+G D C+ G +PN +E ETPL AA G S AK AL G ++ + R+
Sbjct: 455 YGHADVAQLLCSFGSNPNIQDKEE-ETPLHCAAWHGYYSVAK---ALCEAGCNVNIKNRE 510
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T + A + + V+ L E GA N D G L+L+V + + +TLL
Sbjct: 511 GETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAV-RRCQMEVIKTLLSQGCF 569
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ D G +H AC++G + V L +++ N G TPLH+ A N R L
Sbjct: 570 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G EAL +T +A + +A ++ + D
Sbjct: 630 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKD 668
Score = 67.3 bits (157), Expect = 1e-10
Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 3/211 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG +D + K ++ P ++GE L +AA A + L + G+ + + ++
Sbjct: 422 HGHVDTL-KFLSENKCPLDVKDKSGEMALHVAARY-GHADVAQLLCSFGSNPNIQDKEEE 479
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A K L E G + N K+ +G TPL L+ + + + E L A +
Sbjct: 480 TPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPL-LTASARGYHDIVECLAEHGADLN 538
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
A D G +H A R ++ + LL G ++ ++ GNTPLHV + L
Sbjct: 539 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 598
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
C+ + N +TP +A G LD+ +
Sbjct: 599 ANCNLDISNKYGRTPLHLAANNGILDVVRYL 629
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 1/161 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+ G+ + A +++ ++ L++ G+ + +D G +Y + + L + L +
Sbjct: 377 KHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL-KFLSENK 435
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
+ D G +H A R G L +G++ N ++ TPLH A + S A+
Sbjct: 436 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAK 495
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L GC+ N +TP A G D+ E + + +D
Sbjct: 496 ALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 536
>AJ278016-1|CAC04247.1| 784|Homo sapiens protein kinase protein.
Length = 784
Score = 77.0 bits (181), Expect = 2e-13
Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D G++ +H AVE E K LL A+PN + +G TPL+++V + ++ E
Sbjct: 431 VDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVV-EL 489
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL ++ A D W +H A +NG LL A +N + G TP+HV + Q
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 549
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
++ R LL RG D P A G+L + +++
Sbjct: 550 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 589
Score = 62.9 bits (146), Expect = 3e-09
Identities = 45/168 (26%), Positives = 72/168 (42%), Gaps = 2/168 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
+G T MH A + V+ LL G + + PL+ + P++
Sbjct: 536 EGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
++ A L G +H A + G + L+ +D+N + TPLHV A S AR
Sbjct: 596 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARL 655
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRGP 308
LL RG K+A+ T +A G+L +++ K+D + RGP
Sbjct: 656 LLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLA--RGP 701
Score = 56.8 bits (131), Expect = 2e-07
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 4/180 (2%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HGQ + + +G+D + ++ PL AA + + G ++ +T DG
Sbjct: 547 HGQENIVRILLRRGVDVSLQGKDAW-LPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGR 605
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLLHDHATI 202
T +H A ++ + L++L + N TPL+++ T T LLH A
Sbjct: 606 TPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTST--ARLLLHRGAGK 663
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
A G+ +H A RNG + V L+ AD+ AR T LH+ A + +L+
Sbjct: 664 KAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV 723
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/186 (25%), Positives = 75/186 (40%), Gaps = 3/186 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL-GA 166
G TP+ +A I+ L+ G + + +D +H A + L VK L + G
Sbjct: 537 GRTPMHVACQ-HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVD 226
S N + G TPL+L+ + + L+ + + L +H A G
Sbjct: 596 SVNAQTLDGRTPLHLAA-QRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 654
Query: 227 HLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
LL GA A + G T LH+ A N + + L+ D A NQT +A G
Sbjct: 655 LLLHRGAGKKAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 287 NLDLAE 292
+ ++ E
Sbjct: 715 HSEVVE 720
>AB208871-1|BAD92108.1| 1433|Homo sapiens Hypothetical protein
DKFZp781I035 variant protein.
Length = 1433
Score = 77.0 bits (181), Expect = 2e-13
Identities = 49/161 (30%), Positives = 77/161 (47%), Gaps = 3/161 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG C G + N +E GETPL + A + I+ L GA L+ +DG
Sbjct: 491 HGYYSVAKALCEAGCNVNIKNRE-GETPL-LTASARGYHDIVECLAEHGADLNACDKDGH 548
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
A+H AV + +E +KTLL G +Y+D G TPL+++ + P++ L + +
Sbjct: 549 IALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVV-ALCEANCNLD 607
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
++ G +H A NG++ V +L GA + A G T
Sbjct: 608 ISNKYGRTPLHLAANNGILDVVRYLCLMGASVEALTTDGKT 648
Score = 75.4 bits (177), Expect = 5e-13
Identities = 64/219 (29%), Positives = 97/219 (44%), Gaps = 7/219 (3%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRD 141
+G D C+ G +PN +E ETPL AA G S AK AL G ++ + R+
Sbjct: 458 YGHADVAQLLCSFGSNPNIQDKEE-ETPLHCAAWHGYYSVAK---ALCEAGCNVNIKNRE 513
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G T + A + + V+ L E GA N D G L+L+V + + +TLL
Sbjct: 514 GETPLLTASARGYHDIVECLAEHGADLNACDKDGHIALHLAV-RRCQMEVIKTLLSQGCF 572
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ D G +H AC++G + V L +++ N G TPLH+ A N R L
Sbjct: 573 VDYQDRHGNTPLHVACKDGNMPIVVALCEANCNLDISNKYGRTPLHLAANNGILDVVRYL 632
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
G EAL +T +A + +A ++ + D
Sbjct: 633 CLMGASVEALTTDGKTAEDLARSEQHEHVAGLLARLRKD 671
Score = 67.3 bits (157), Expect = 1e-10
Identities = 55/211 (26%), Positives = 93/211 (44%), Gaps = 3/211 (1%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HG +D + K ++ P ++GE L +AA A + L + G+ + + ++
Sbjct: 425 HGHVDTL-KFLSENKCPLDVKDKSGEMALHVAARY-GHADVAQLLCSFGSNPNIQDKEEE 482
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A K L E G + N K+ +G TPL L+ + + + E L A +
Sbjct: 483 TPLHCAAWHGYYSVAKALCEAGCNVNIKNREGETPL-LTASARGYHDIVECLAEHGADLN 541
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
A D G +H A R ++ + LL G ++ ++ GNTPLHV + L
Sbjct: 542 ACDKDGHIALHLAVRRCQMEVIKTLLSQGCFVDYQDRHGNTPLHVACKDGNMPIVVALCE 601
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
C+ + N +TP +A G LD+ +
Sbjct: 602 ANCNLDISNKYGRTPLHLAANNGILDVVRYL 632
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/161 (22%), Positives = 69/161 (42%), Gaps = 1/161 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+ G+ + A +++ ++ L++ G+ + +D G +Y + + L + L +
Sbjct: 380 KHGTPPLLIAAGCGNIQILQLLIKRGSRIDVQDKGGSNAVYWAARHGHVDTL-KFLSENK 438
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
+ D G +H A R G L +G++ N ++ TPLH A + S A+
Sbjct: 439 CPLDVKDKSGEMALHVAARYGHADVAQLLCSFGSNPNIQDKEEETPLHCAAWHGYYSVAK 498
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L GC+ N +TP A G D+ E + + +D
Sbjct: 499 ALCEAGCNVNIKNREGETPLLTASARGYHDIVECLAEHGAD 539
>AB047783-1|BAB56136.1| 784|Homo sapiens probable dual-specificity
Ser/Thr/Tyr kinase protein.
Length = 784
Score = 77.0 bits (181), Expect = 2e-13
Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D G++ +H AVE E K LL A+PN + +G TPL+++V + ++ E
Sbjct: 431 VDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVV-EL 489
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL ++ A D W +H A +NG LL A +N + G TP+HV + Q
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 549
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
++ R LL RG D P A G+L + +++
Sbjct: 550 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 589
Score = 64.5 bits (150), Expect = 9e-10
Identities = 46/168 (27%), Positives = 72/168 (42%), Gaps = 2/168 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
+G T MH A + V+ LL G + + PL+ + P++
Sbjct: 536 EGRTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
++ A L G +H A + G + L+ +D+N + TPLHV A S AR
Sbjct: 596 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARL 655
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRGP 308
LL RG KEA+ T +A G+L +++ K+D + RGP
Sbjct: 656 LLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLA--RGP 701
Score = 56.8 bits (131), Expect = 2e-07
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 4/180 (2%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HGQ + + +G+D + ++ PL AA + + G ++ +T DG
Sbjct: 547 HGQENIVRILLRRGVDVSLQGKDAW-LPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGR 605
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLLHDHATI 202
T +H A ++ + L++L + N TPL+++ T T LLH A
Sbjct: 606 TPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTST--ARLLLHRGAGK 663
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
A G+ +H A RNG + V L+ AD+ AR T LH+ A + +L+
Sbjct: 664 EAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV 723
Score = 50.4 bits (115), Expect = 2e-05
Identities = 47/186 (25%), Positives = 75/186 (40%), Gaps = 3/186 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL-GA 166
G TP+ +A I+ L+ G + + +D +H A + L VK L + G
Sbjct: 537 GRTPMHVACQ-HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVD 226
S N + G TPL+L+ + + L+ + + L +H A G
Sbjct: 596 SVNAQTLDGRTPLHLAA-QRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 654
Query: 227 HLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
LL GA A + G T LH+ A N + + L+ D A NQT +A G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 287 NLDLAE 292
+ ++ E
Sbjct: 715 HSEVVE 720
>AB023174-1|BAA76801.2| 693|Homo sapiens KIAA0957 protein protein.
Length = 693
Score = 77.0 bits (181), Expect = 2e-13
Identities = 51/182 (28%), Positives = 85/182 (46%), Gaps = 4/182 (2%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A K + ++ L+N GA + T+ G T +H A K L V+ LL+ G + +D
Sbjct: 16 LVAAYKGQTENVVQLINKGARVAV-TKHGRTPLHLAANKGHLPVVQILLKAGCDLDVQDD 74
Query: 174 KGLTPLY-LSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T L+ +V T+ + L+H+ + D G +H+A +G Q L+ G
Sbjct: 75 GDQTALHRATVVGNTE--IIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAG 132
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAE 292
A++ A+N +GNT LH+ N+ R LL G + N A T VA +L +
Sbjct: 133 ANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIR 192
Query: 293 VI 294
++
Sbjct: 193 LL 194
Score = 71.7 bits (168), Expect = 6e-12
Identities = 53/187 (28%), Positives = 88/187 (47%), Gaps = 1/187 (0%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL 164
Q+ G+ A + +I+ AL++ G LD + +DG+TA+H A ++ K L++
Sbjct: 72 QDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKA 131
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
GA+ K+ G T L+L+ N + LL + + G +H A R +
Sbjct: 132 GANVLAKNKAGNTALHLACQN-SHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSI 190
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
+ LL ++ +N +G+T LHV A A+ LL G D +N A QTP + A
Sbjct: 191 IRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARY 250
Query: 285 AGNLDLA 291
N ++A
Sbjct: 251 HNNPEVA 257
Score = 70.5 bits (165), Expect = 1e-11
Identities = 60/227 (26%), Positives = 97/227 (42%), Gaps = 4/227 (1%)
Query: 77 RFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLD 136
R L GQ + + + KG + G TPL +AA K ++ L+ G LD
Sbjct: 14 RLLVAAYKGQTENVVQLINKGA--RVAVTKHGRTPLHLAAN-KGHLPVVQILLKAGCDLD 70
Query: 137 YRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLL 196
+ TA+HRA + E + L+ G + + +D G T L+ + + + L+
Sbjct: 71 VQDDGDQTALHRATVVGNTEIIAALIHEGCALDRQDKDGNTALHEASWHGFSQS-AKLLV 129
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDS 256
A + A + G +H AC+N Q LL G+ + +N +G+T LHV A S
Sbjct: 130 KAGANVLAKNKAGNTALHLACQNSHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLS 189
Query: 257 CARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIV 303
R LL C N A T VA + +A+++ +D +
Sbjct: 190 IIRLLLTAFCSVHEKNQAGDTALHVAAALNHKKVAKILLEAGADTTI 236
>X69838-1|CAA49491.1| 1001|Homo sapiens G9a protein.
Length = 1001
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 439 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 497
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 498 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 557
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 558 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 617
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 618 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 649
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 511 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 569
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 570 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 628
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 629 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 681
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 443 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 502
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 503 NAVDKQQRTPLMEAVVNNHLEVA 525
>BX005460-6|CAM26152.1| 922|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 922
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 360 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 418
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 419 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 478
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 479 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 538
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 539 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 570
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 432 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 490
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 491 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 549
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 550 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 602
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 364 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 423
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 424 NAVDKQQRTPLMEAVVNNHLEVA 446
>BX005460-5|CAM26151.1| 888|Homo sapiens euchromatic histone-lysine
N-methyltransferase 2 protein.
Length = 888
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 326 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 384
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 385 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 444
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 445 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 504
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 505 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 536
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 398 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 456
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 457 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 515
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 516 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 568
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 330 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 389
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 390 NAVDKQQRTPLMEAVVNNHLEVA 412
>BC075088-1|AAH75088.1| 453|Homo sapiens ankyrin repeat and SOCS
box-containing protein 16 protein.
Length = 453
Score = 76.6 bits (180), Expect = 2e-13
Identities = 62/187 (33%), Positives = 86/187 (45%), Gaps = 13/187 (6%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA LD R G A+H A + + V+ LL GA N +G TPL+L ++
Sbjct: 130 LIRQGAELDARV-GGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPES 188
Query: 188 DPLLC-ETLLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
L C + LL AT+ + + +H A GL QHV L +GAD+ R + G T
Sbjct: 189 --LQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETA 246
Query: 246 LHVCAVNAQ--DSC------ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
L+ A+ SC AR+LL G D A TP A +G LAE++ Y
Sbjct: 247 LNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRY 306
Query: 298 KSDEIVP 304
+ VP
Sbjct: 307 GARAEVP 313
Score = 57.2 bits (132), Expect = 1e-07
Identities = 50/167 (29%), Positives = 70/167 (41%), Gaps = 10/167 (5%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGL-TPLYLSVTNK 186
L+ GA + T +G+T +H SL+ K LLE GA+ N G+ TPL+++
Sbjct: 162 LLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARG 221
Query: 187 TDPLLCETLLHDHATIGATDLQGWQEVHQACRNG-----LVQH---VDHLLFYGADMNAR 238
+ + L H A +G QG ++ AC +H LL GAD A
Sbjct: 222 LEQHVALYLEHG-ADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAA 280
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+TPLH + A LL G E N A TP A+ A
Sbjct: 281 GRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQA 327
Score = 44.4 bits (100), Expect = 0.001
Identities = 48/186 (25%), Positives = 72/186 (38%), Gaps = 12/186 (6%)
Query: 80 EHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRT 139
E Q D + G N +E G TPL + + + L+ GA ++
Sbjct: 149 EACARAQFDCVRLLLTFGAKANVLTEE-GTTPLHLCT-IPESLQCAKLLLEAGATVNLAA 206
Query: 140 RDGS-TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET---- 194
+ T +H A + + V LE GA + +G T L + P C
Sbjct: 207 GESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAA 266
Query: 195 ---LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAV 251
LL A A + +H AC +G + LL YGA N +G+TP+ CA+
Sbjct: 267 ARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTPMD-CAL 325
Query: 252 NA-QDS 256
A QD+
Sbjct: 326 QAVQDA 331
>BC020970-1|AAH20970.2| 1198|Homo sapiens EHMT2 protein protein.
Length = 1198
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 636 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 694
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 695 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 754
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 755 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 814
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 815 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 846
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 708 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 766
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 767 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 825
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 826 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 878
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 640 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 699
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 700 NAVDKQQRTPLMEAVVNNHLEVA 722
>BC018718-1|AAH18718.1| 1001|Homo sapiens EHMT2 protein protein.
Length = 1001
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 439 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 497
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 498 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 557
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 558 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 617
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 618 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 649
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 511 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 569
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 570 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 628
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 629 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 681
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 443 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 502
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 503 NAVDKQQRTPLMEAVVNNHLEVA 525
>BC009351-1|AAH09351.1| 1209|Homo sapiens EHMT2 protein protein.
Length = 1209
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 647 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 705
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 706 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 765
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 766 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 825
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 826 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 857
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 719 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 777
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 778 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 836
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 837 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 889
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 651 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 710
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 711 NAVDKQQRTPLMEAVVNNHLEVA 733
>BC002686-1|AAH02686.2| 1043|Homo sapiens EHMT2 protein protein.
Length = 1043
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 481 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 539
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 540 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 599
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 600 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 659
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 660 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 691
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 553 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 611
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 612 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 670
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 671 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 723
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 485 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 544
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 545 NAVDKQQRTPLMEAVVNNHLEVA 567
>BA000025-4|BAB63295.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 439 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 497
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 498 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 557
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 558 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 617
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 618 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 649
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 511 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 569
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 570 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 628
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 629 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 681
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 443 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 502
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 503 NAVDKQQRTPLMEAVVNNHLEVA 525
>AL844853-4|CAI41853.1| 1210|Homo sapiens HLA-B associated
transcript 8 protein.
Length = 1210
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 648 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 706
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 707 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 766
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 767 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 826
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 827 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 858
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 720 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 778
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 779 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 837
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 838 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 890
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 652 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 711
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 712 NAVDKQQRTPLMEAVVNNHLEVA 734
>AL844853-3|CAI41852.1| 1176|Homo sapiens HLA-B associated
transcript 8 protein.
Length = 1176
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 614 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 672
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 673 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 732
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 733 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 792
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 793 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 824
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 686 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 744
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 745 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 803
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 804 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 856
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 618 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 677
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 678 NAVDKQQRTPLMEAVVNNHLEVA 700
>AL671762-16|CAI18224.2| 1210|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1210
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 648 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 706
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 707 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 766
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 767 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 826
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 827 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 858
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 720 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 778
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 779 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 837
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 838 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 890
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 652 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 711
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 712 NAVDKQQRTPLMEAVVNNHLEVA 734
>AL671762-15|CAI18226.2| 1176|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1176
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 614 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 672
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 673 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 732
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 733 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 792
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 793 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 824
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 686 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 744
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 745 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 803
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 804 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 856
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 618 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 677
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 678 NAVDKQQRTPLMEAVVNNHLEVA 700
>AL671762-14|CAM25534.1| 1267|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1267
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 705 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 763
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 764 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 823
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 824 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 883
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 884 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 915
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 777 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 835
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 836 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 894
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 895 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 947
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 709 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 768
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 769 NAVDKQQRTPLMEAVVNNHLEVA 791
>AL671762-13|CAM25533.1| 1233|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1233
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 671 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 729
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 730 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 789
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 790 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 849
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 850 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 881
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 743 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 801
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 802 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 860
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 861 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 913
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 675 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 734
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 735 NAVDKQQRTPLMEAVVNNHLEVA 757
>AL662834-27|CAI17747.2| 1176|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1176
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 614 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 672
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 673 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 732
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 733 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 792
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 793 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 824
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 686 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 744
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 745 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 803
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 804 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 856
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 618 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 677
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 678 NAVDKQQRTPLMEAVVNNHLEVA 700
>AL662834-26|CAI17748.1| 1210|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1210
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 648 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 706
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 707 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 766
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 767 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 826
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 827 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 858
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 720 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 778
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 779 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 837
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 838 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 890
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 652 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 711
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 712 NAVDKQQRTPLMEAVVNNHLEVA 734
>AL662834-25|CAM24993.1| 1267|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1267
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 705 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 763
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 764 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 823
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 824 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 883
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 884 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 915
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 777 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 835
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 836 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 894
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 895 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 947
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 709 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 768
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 769 NAVDKQQRTPLMEAVVNNHLEVA 791
>AL662834-24|CAM24992.1| 1233|Homo sapiens euchromatic
histone-lysine N-methyltransferase 2 protein.
Length = 1233
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 671 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 729
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 730 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 789
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 790 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 849
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 850 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 881
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 743 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 801
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 802 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 860
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 861 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 913
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 675 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 734
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 735 NAVDKQQRTPLMEAVVNNHLEVA 757
>AK054727-1|BAB70800.1| 453|Homo sapiens protein ( Homo sapiens
cDNA FLJ30165 fis, clone BRACE2000698, weakly similar to
ANKYRIN 2. ).
Length = 453
Score = 76.6 bits (180), Expect = 2e-13
Identities = 62/187 (33%), Positives = 86/187 (45%), Gaps = 13/187 (6%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA LD R G A+H A + + V+ LL GA N +G TPL+L ++
Sbjct: 130 LIRQGAELDARV-GGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPES 188
Query: 188 DPLLC-ETLLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
L C + LL AT+ + + +H A GL QHV L +GAD+ R + G T
Sbjct: 189 --LQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETA 246
Query: 246 LHVCAVNAQ--DSC------ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
L+ A+ SC AR+LL G D A TP A +G LAE++ Y
Sbjct: 247 LNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRY 306
Query: 298 KSDEIVP 304
+ VP
Sbjct: 307 GARAEVP 313
Score = 57.2 bits (132), Expect = 1e-07
Identities = 50/167 (29%), Positives = 70/167 (41%), Gaps = 10/167 (5%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGL-TPLYLSVTNK 186
L+ GA + T +G+T +H SL+ K LLE GA+ N G+ TPL+++
Sbjct: 162 LLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARG 221
Query: 187 TDPLLCETLLHDHATIGATDLQGWQEVHQACRNG-----LVQH---VDHLLFYGADMNAR 238
+ + L H A +G QG ++ AC +H LL GAD A
Sbjct: 222 LEQHVALYLEHG-ADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAA 280
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+TPLH + A LL G E N A TP A+ A
Sbjct: 281 GRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQA 327
Score = 44.4 bits (100), Expect = 0.001
Identities = 48/186 (25%), Positives = 72/186 (38%), Gaps = 12/186 (6%)
Query: 80 EHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRT 139
E Q D + G N +E G TPL + + + L+ GA ++
Sbjct: 149 EACARAQFDCVRLLLTFGAKANVLTEE-GTTPLHLCT-IPESLQCAKLLLEAGATVNLAA 206
Query: 140 RDGS-TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET---- 194
+ T +H A + + V LE GA + +G T L + P C
Sbjct: 207 GESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAA 266
Query: 195 ---LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAV 251
LL A A + +H AC +G + LL YGA N +G+TP+ CA+
Sbjct: 267 ARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTPMD-CAL 325
Query: 252 NA-QDS 256
A QD+
Sbjct: 326 QAVQDA 331
>AJ315532-1|CAC86666.1| 1210|Homo sapiens NG36/G9a protein.
Length = 1210
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 648 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 706
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 707 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 766
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 767 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 826
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 827 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 858
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 720 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 778
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 779 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 837
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 838 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 890
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 652 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 711
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 712 NAVDKQQRTPLMEAVVNNHLEVA 734
>AF403034-1|AAL57353.1| 253|Homo sapiens ankyrin repeat
domain-containing SOCS box protein Asb-16 protein.
Length = 253
Score = 76.6 bits (180), Expect = 2e-13
Identities = 62/187 (33%), Positives = 86/187 (45%), Gaps = 13/187 (6%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA LD R G A+H A + + V+ LL GA N +G TPL+L ++
Sbjct: 29 LIRQGAELDARV-GGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPES 87
Query: 188 DPLLC-ETLLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
L C + LL AT+ + + +H A GL QHV L +GAD+ R + G T
Sbjct: 88 --LQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETA 145
Query: 246 LHVCAVNAQ--DSC------ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
L+ A+ SC AR+LL G D A TP A +G LAE++ Y
Sbjct: 146 LNAACAGAEGPGSCRRHQAAARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRY 205
Query: 298 KSDEIVP 304
+ VP
Sbjct: 206 GARAEVP 212
Score = 57.2 bits (132), Expect = 1e-07
Identities = 50/167 (29%), Positives = 70/167 (41%), Gaps = 10/167 (5%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGL-TPLYLSVTNK 186
L+ GA + T +G+T +H SL+ K LLE GA+ N G+ TPL+++
Sbjct: 61 LLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATVNLAAGESQETPLHVAAARG 120
Query: 187 TDPLLCETLLHDHATIGATDLQGWQEVHQACRNG-----LVQH---VDHLLFYGADMNAR 238
+ + L H A +G QG ++ AC +H LL GAD A
Sbjct: 121 LEQHVALYLEHG-ADVGLRTSQGETALNAACAGAEGPGSCRRHQAAARRLLEAGADARAA 179
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+TPLH + A LL G E N A TP A+ A
Sbjct: 180 GRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTPMDCALQA 226
Score = 44.4 bits (100), Expect = 0.001
Identities = 48/186 (25%), Positives = 72/186 (38%), Gaps = 12/186 (6%)
Query: 80 EHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRT 139
E Q D + G N +E G TPL + + + L+ GA ++
Sbjct: 48 EACARAQFDCVRLLLTFGAKANVLTEE-GTTPLHLCT-IPESLQCAKLLLEAGATVNLAA 105
Query: 140 RDGS-TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET---- 194
+ T +H A + + V LE GA + +G T L + P C
Sbjct: 106 GESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETALNAACAGAEGPGSCRRHQAA 165
Query: 195 ---LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAV 251
LL A A + +H AC +G + LL YGA N +G+TP+ CA+
Sbjct: 166 ARRLLEAGADARAAGRKRHTPLHNACASGCGGLAELLLRYGARAEVPNGAGHTPMD-CAL 224
Query: 252 NA-QDS 256
A QD+
Sbjct: 225 QAVQDA 230
>AF134726-3|AAD21812.1| 1001|Homo sapiens G9A protein.
Length = 1001
Score = 76.6 bits (180), Expect = 2e-13
Identities = 56/212 (26%), Positives = 91/212 (42%), Gaps = 2/212 (0%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 439 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 497
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 498 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 557
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ L + A D GW + A + ++ + LL GAD+ + N LH +
Sbjct: 558 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNEENICLHWAS 617
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
+ A LL CD A+N+ TP +A
Sbjct: 618 FTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 649
Score = 66.1 bits (154), Expect = 3e-10
Identities = 50/173 (28%), Positives = 79/173 (45%), Gaps = 3/173 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 511 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 569
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
N +D G TP+ + +K ++ LL A + TD + +H A G + L
Sbjct: 570 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNEENICLHWASFTGSAAIAEVL 628
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
L D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 629 LNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 681
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 443 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 502
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 503 NAVDKQQRTPLMEAVVNNHLEVA 525
>BC016985-1|AAH16985.2| 579|Homo sapiens ANKRD44 protein protein.
Length = 579
Score = 76.2 bits (179), Expect = 3e-13
Identities = 54/187 (28%), Positives = 89/187 (47%), Gaps = 2/187 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL +AA L A+I+ L+ GA ++ + T +HRAV S EAV+ L++ A N
Sbjct: 43 TPLHVAAFL-GDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVN 101
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
+D TPL+++ NK E ++ +++ +D G +H A NG V+ V+ LL
Sbjct: 102 ARDKNWQTPLHVAAANKA-VKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLL 160
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
GA++NA + LH A L+ G + + TP A G ++
Sbjct: 161 AKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQIN 220
Query: 290 LAEVIKN 296
+ + + N
Sbjct: 221 VVKHLLN 227
Score = 72.9 bits (171), Expect = 2e-12
Identities = 54/216 (25%), Positives = 90/216 (41%), Gaps = 5/216 (2%)
Query: 76 RRFLEHVTH-GQIDKITKACAKGLDPNFHCQET-GETPLTIAAGLKSPAKILIALVNGGA 133
RR L + G +D + G + C++ G TPL AA ++ L+N G
Sbjct: 174 RRALHWAAYMGHLDVVALLINHGAEVT--CKDKKGYTPLHAAAS-NGQINVVKHLLNLGV 230
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
+D G+TA+H A V L++ GA+ N + G TPL+ + + L E
Sbjct: 231 EIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLE 290
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
L+++ A + G +H +G L+ G +++ + GNTPLHV A
Sbjct: 291 LLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYG 350
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
+ L+ G D + P +A + + D
Sbjct: 351 HELLINTLITSGADTAKCGIHSMFPLHLAALNAHSD 386
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 2/177 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL A +S + + L+ A ++ R ++ T +H A +++ + ++ L +S N
Sbjct: 76 TPLHRAVASRSEEAVQV-LIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVN 134
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
D G T L+ + N ++ LL A I A D + + +H A G + V L+
Sbjct: 135 VSDRGGRTALHHAALNGHVEMV-NLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLI 193
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
+GA++ ++ G TPLH A N Q + + LL G + + +N T +A G
Sbjct: 194 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNG 250
Score = 66.1 bits (154), Expect = 3e-10
Identities = 53/219 (24%), Positives = 100/219 (45%), Gaps = 4/219 (1%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
++GQI+ + G++ + G T L IA A ++ L++ GA ++ +G
Sbjct: 215 SNGQINVVKHLLNLGVEID-EINVYGNTALHIACYNGQDA-VVNELIDYGANVNQPNNNG 272
Query: 143 STAMH-RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
T +H A + ++ L+ GA N + G +PL+++ + +TL+ +
Sbjct: 273 FTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTR-SQTLIQNGGE 331
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
I D G +H A R G ++ L+ GAD PLH+ A+NA C R+L
Sbjct: 332 IDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKL 391
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L G + + + +T A GN++ +++++ +D
Sbjct: 392 LSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGAD 430
Score = 63.7 bits (148), Expect = 2e-09
Identities = 48/195 (24%), Positives = 92/195 (47%), Gaps = 4/195 (2%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
T + PL A P +I + L++ ++ + T +H A E ++ L+ GA
Sbjct: 7 TDQPPLVQAIFSGDPEEIRM-LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGA 65
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQE-VHQACRNGLVQHV 225
N KD LTPL+ +V ++++ + + L+ A + A D + WQ +H A N V+
Sbjct: 66 RVNAKDNMWLTPLHRAVASRSEEAV-QVLIKHSADVNARD-KNWQTPLHVAAANKAVKCA 123
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
+ ++ + +N + G T LH A+N LL +G + A + ++ A
Sbjct: 124 EVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLLAKGANINAFDKKDRRALHWAAYM 183
Query: 286 GNLDLAEVIKNYKSD 300
G+LD+ ++ N+ ++
Sbjct: 184 GHLDVVALLINHGAE 198
Score = 63.7 bits (148), Expect = 2e-09
Identities = 56/212 (26%), Positives = 87/212 (41%), Gaps = 5/212 (2%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
THG + + G D N ++ G++PL + A + + NGG + D +DG
Sbjct: 283 THGALC-LELLVNNGADVNIQSKD-GKSPLHMTAVHGRFTRSQTLIQNGGEI-DCVDKDG 339
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
+T +H A + TL+ GA + PL+L+ N C LL I
Sbjct: 340 NTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDC-CRKLLSSGFEI 398
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D G +H A G V+ + L GAD + ++ G TPLH A N C L+
Sbjct: 399 DTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLV 458
Query: 263 FRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
G + + +T A A ++D + I
Sbjct: 459 TTGANVNETDDWGRTALHYAA-ASDMDRNKTI 489
Score = 44.0 bits (99), Expect = 0.001
Identities = 33/120 (27%), Positives = 50/120 (41%)
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
DP L+H + D + +H A G + ++ L+ GA +NA++ TPLH
Sbjct: 20 DPEEIRMLIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLH 79
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRG 307
+ + + L+ D A + QTP VA + AEVI S V RG
Sbjct: 80 RAVASRSEEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRG 139
>AK097086-1|BAC04946.1| 919|Homo sapiens protein ( Homo sapiens
cDNA FLJ39767 fis, clone SPLEN2000607, weakly similar to
ANKYRIN 1. ).
Length = 919
Score = 76.2 bits (179), Expect = 3e-13
Identities = 54/187 (28%), Positives = 89/187 (47%), Gaps = 2/187 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL +AA L A+I+ L+ GA ++ + T +HRAV S EAV+ L++ A N
Sbjct: 18 TPLHVAAFL-GDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVN 76
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
+D TPL+++ NK E ++ +++ +D G +H A NG V+ V+ LL
Sbjct: 77 ARDKNWQTPLHVAAANKA-VKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLL 135
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
GA++NA + LH A L+ G + + TP A G ++
Sbjct: 136 AKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQIN 195
Query: 290 LAEVIKN 296
+ + + N
Sbjct: 196 VVKHLLN 202
Score = 71.3 bits (167), Expect = 8e-12
Identities = 54/216 (25%), Positives = 89/216 (41%), Gaps = 5/216 (2%)
Query: 76 RRFLEHVTH-GQIDKITKACAKGLDPNFHCQET-GETPLTIAAGLKSPAKILIALVNGGA 133
RR L + G +D + G + C++ G TPL AA ++ L+N G
Sbjct: 149 RRALHWAAYMGHLDVVALLINHGAEVT--CKDKKGYTPLHAAAS-NGQINVVKHLLNLGV 205
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
+D G+TA+H A V L++ GA+ N + G TPL+ + + L E
Sbjct: 206 EIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLE 265
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
L+++ A + G +H +G L+ G +++ + GNTPLHV A
Sbjct: 266 LLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYG 325
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
+ L G D + P +A + + D
Sbjct: 326 HELLINTLRTSGADTAKCGIHSMFPLHLAALNAHSD 361
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 2/177 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL A +S + + L+ A ++ R ++ T +H A +++ + ++ L +S N
Sbjct: 51 TPLHRAVASRSEEAVQV-LIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVN 109
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
D G T L+ + N ++ LL A I A D + + +H A G + V L+
Sbjct: 110 VSDRGGRTALHHAALNGHVEMV-NLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLI 168
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
+GA++ ++ G TPLH A N Q + + LL G + + +N T +A G
Sbjct: 169 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNG 225
Score = 65.7 bits (153), Expect = 4e-10
Identities = 59/201 (29%), Positives = 88/201 (43%), Gaps = 11/201 (5%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR-DGSTAMHRAVEKNSLEAVKTLLEL 164
E G T L +AA K + + AL+N GA + + T +H +V ++ LLE+
Sbjct: 573 EKGRTALDLAA-FKGHTECVEALINPGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEI 631
Query: 165 GASP---NYKDGKGLTPLYLSVT-NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG 220
+P + KD KG TPL L+V D + LL A + D+ G +H+ G
Sbjct: 632 ADNPEAVDVKDAKGQTPLMLAVAYGHIDAV--SLLLEKEANVDTVDILGCTALHRGIMTG 689
Query: 221 LVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFA-NQ--T 277
+ V LL + +++ G TPLH A + +LL +E F NQ T
Sbjct: 690 HEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYT 749
Query: 278 PYQVAVIAGNLDLAEVIKNYK 298
P A GN + EV+ K
Sbjct: 750 PLHWACYNGNENCIEVLLEQK 770
Score = 64.5 bits (150), Expect = 9e-10
Identities = 53/219 (24%), Positives = 99/219 (45%), Gaps = 4/219 (1%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
++GQI+ + G++ + G T L IA A ++ L++ GA ++ +G
Sbjct: 190 SNGQINVVKHLLNLGVEID-EINVYGNTALHIACYNGQDA-VVNELIDYGANVNQPNNNG 247
Query: 143 STAMH-RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
T +H A + ++ L+ GA N + G +PL+++ + +TL+ +
Sbjct: 248 FTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTR-SQTLIQNGGE 306
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
I D G +H A R G ++ L GAD PLH+ A+NA C R+L
Sbjct: 307 IDCVDKDGNTPLHVAARYGHELLINTLRTSGADTAKCGIHSMFPLHLAALNAHSDCCRKL 366
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L G + + + +T A GN++ +++++ +D
Sbjct: 367 LSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGAD 405
Score = 63.3 bits (147), Expect = 2e-09
Identities = 44/168 (26%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Query: 136 DYRTRDGS--TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
D T D T +H A E ++ L+ GA N KD LTPL+ +V ++++ + +
Sbjct: 8 DVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAV-Q 66
Query: 194 TLLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVN 252
L+ A + A D + WQ +H A N V+ + ++ + +N + G T LH A+N
Sbjct: 67 VLIKHSADVNARD-KNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALN 125
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
LL +G + A + ++ A G+LD+ ++ N+ ++
Sbjct: 126 GHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAE 173
Score = 62.1 bits (144), Expect = 5e-09
Identities = 56/212 (26%), Positives = 86/212 (40%), Gaps = 5/212 (2%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
THG + + G D N ++ G++PL + A + + NGG + D +DG
Sbjct: 258 THGALC-LELLVNNGADVNIQSKD-GKSPLHMTAVHGRFTRSQTLIQNGGEI-DCVDKDG 314
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
+T +H A + TL GA + PL+L+ N C LL I
Sbjct: 315 NTPLHVAARYGHELLINTLRTSGADTAKCGIHSMFPLHLAALNAHSDC-CRKLLSSGFEI 373
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D G +H A G V+ + L GAD + ++ G TPLH A N C L+
Sbjct: 374 DTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLV 433
Query: 263 FRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
G + + +T A A ++D + I
Sbjct: 434 TTGANVNETDDWGRTALHYAA-ASDMDRNKTI 464
Score = 55.2 bits (127), Expect = 5e-07
Identities = 59/211 (27%), Positives = 90/211 (42%), Gaps = 9/211 (4%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
++PL +AA + L L+ LD R G TA+ A K E V+ L+ GAS
Sbjct: 543 KSPLHLAA-YNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINPGASI 601
Query: 169 NYKDG-KGLTPLYLSVTNKTDPLLCETLLHDHA----TIGATDLQGWQEVHQACRNGLVQ 223
KD TPL+ SV N LC LL + A + D +G + A G +
Sbjct: 602 FVKDNVTKRTPLHASVIN--GHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHID 659
Query: 224 HVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
V LL A+++ + G T LH + + C + LL + + +TP A
Sbjct: 660 AVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAA 719
Query: 284 IAGNLD-LAEVIKNYKSDEIVPFRGPPRYNP 313
G+ L+E+++ S+E F+ Y P
Sbjct: 720 ARGHATWLSELLQMALSEEDCCFKDNQGYTP 750
Score = 46.4 bits (105), Expect = 2e-04
Identities = 34/107 (31%), Positives = 49/107 (45%), Gaps = 4/107 (3%)
Query: 171 KDGKGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
+D KG TPL + D + C LL H A + A D G + A NG VD L+
Sbjct: 810 RDDKGRTPLRAAAF--ADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILV 867
Query: 230 FYG-ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
AD+ ++ NTPLH+ + CA +L + D+ +N N
Sbjct: 868 NSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESLINEKN 914
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/113 (27%), Positives = 48/113 (42%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
L+H + D + +H A G + ++ L+ GA +NA++ TPLH +
Sbjct: 2 LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRS 61
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRG 307
+ + L+ D A + QTP VA + AEVI S V RG
Sbjct: 62 EEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRG 114
Score = 34.7 bits (76), Expect = 0.81
Identities = 35/160 (21%), Positives = 62/160 (38%), Gaps = 7/160 (4%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPN---YKDGKGLTPLYLSVTNKTDPLLCETLLHD 198
G T +H A + + LL++ S +KD +G TPL+ + N + C +L +
Sbjct: 711 GRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNEN--CIEVLLE 768
Query: 199 HATIGATDLQGWQEVHQACRNGLVQHVDHLL--FYGADMNARNASGNTPLHVCAVNAQDS 256
+ +H A N LL + ++ R+ G TPL A
Sbjct: 769 QKCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLRAAAFADHVE 828
Query: 257 CARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
C + LL A++ + +T +A G +++ N
Sbjct: 829 CLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVN 868
>AC013264-1|AAX93155.1| 525|Homo sapiens unknown protein.
Length = 525
Score = 76.2 bits (179), Expect = 3e-13
Identities = 54/187 (28%), Positives = 89/187 (47%), Gaps = 2/187 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL +AA L A+I+ L+ GA ++ + T +HRAV S EAV+ L++ A N
Sbjct: 18 TPLHVAAFL-GDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAVQVLIKHSADVN 76
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
+D TPL+++ NK E ++ +++ +D G +H A NG V+ V+ LL
Sbjct: 77 ARDKNWQTPLHVAAANKA-VKCAEVIIPLLSSVNVSDRGGRTALHHAALNGHVEMVNLLL 135
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
GA++NA + LH A L+ G + + TP A G ++
Sbjct: 136 AKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAEVTCKDKKGYTPLHAAASNGQIN 195
Query: 290 LAEVIKN 296
+ + + N
Sbjct: 196 VVKHLLN 202
Score = 72.9 bits (171), Expect = 2e-12
Identities = 54/216 (25%), Positives = 90/216 (41%), Gaps = 5/216 (2%)
Query: 76 RRFLEHVTH-GQIDKITKACAKGLDPNFHCQET-GETPLTIAAGLKSPAKILIALVNGGA 133
RR L + G +D + G + C++ G TPL AA ++ L+N G
Sbjct: 149 RRALHWAAYMGHLDVVALLINHGAEVT--CKDKKGYTPLHAAAS-NGQINVVKHLLNLGV 205
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
+D G+TA+H A V L++ GA+ N + G TPL+ + + L E
Sbjct: 206 EIDEINVYGNTALHIACYNGQDAVVNELIDYGANVNQPNNNGFTPLHFAAASTHGALCLE 265
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
L+++ A + G +H +G L+ G +++ + GNTPLHV A
Sbjct: 266 LLVNNGADVNIQSKDGKSPLHMTAVHGRFTRSQTLIQNGGEIDCVDKDGNTPLHVAARYG 325
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
+ L+ G D + P +A + + D
Sbjct: 326 HELLINTLITSGADTAKCGIHSMFPLHLAALNAHSD 361
Score = 66.9 bits (156), Expect = 2e-10
Identities = 47/177 (26%), Positives = 83/177 (46%), Gaps = 2/177 (1%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL A +S + + L+ A ++ R ++ T +H A +++ + ++ L +S N
Sbjct: 51 TPLHRAVASRSEEAVQV-LIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVN 109
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
D G T L+ + N ++ LL A I A D + + +H A G + V L+
Sbjct: 110 VSDRGGRTALHHAALNGHVEMV-NLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLI 168
Query: 230 FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
+GA++ ++ G TPLH A N Q + + LL G + + +N T +A G
Sbjct: 169 NHGAEVTCKDKKGYTPLHAAASNGQINVVKHLLNLGVEIDEINVYGNTALHIACYNG 225
Score = 66.1 bits (154), Expect = 3e-10
Identities = 53/219 (24%), Positives = 100/219 (45%), Gaps = 4/219 (1%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
++GQI+ + G++ + G T L IA A ++ L++ GA ++ +G
Sbjct: 190 SNGQINVVKHLLNLGVEID-EINVYGNTALHIACYNGQDA-VVNELIDYGANVNQPNNNG 247
Query: 143 STAMH-RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
T +H A + ++ L+ GA N + G +PL+++ + +TL+ +
Sbjct: 248 FTPLHFAAASTHGALCLELLVNNGADVNIQSKDGKSPLHMTAVHGRFTR-SQTLIQNGGE 306
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
I D G +H A R G ++ L+ GAD PLH+ A+NA C R+L
Sbjct: 307 IDCVDKDGNTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDCCRKL 366
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L G + + + +T A GN++ +++++ +D
Sbjct: 367 LSSGFEIDTPDKFGRTCLHAAAAGGNVECIKLLQSSGAD 405
Score = 63.7 bits (148), Expect = 2e-09
Identities = 56/212 (26%), Positives = 87/212 (41%), Gaps = 5/212 (2%)
Query: 83 THGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDG 142
THG + + G D N ++ G++PL + A + + NGG + D +DG
Sbjct: 258 THGALC-LELLVNNGADVNIQSKD-GKSPLHMTAVHGRFTRSQTLIQNGGEI-DCVDKDG 314
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
+T +H A + TL+ GA + PL+L+ N C LL I
Sbjct: 315 NTPLHVAARYGHELLINTLITSGADTAKCGIHSMFPLHLAALNAHSDC-CRKLLSSGFEI 373
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D G +H A G V+ + L GAD + ++ G TPLH A N C L+
Sbjct: 374 DTPDKFGRTCLHAAAAGGNVECIKLLQSSGADFHKKDKCGRTPLHYAAANCHFHCIETLV 433
Query: 263 FRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
G + + +T A A ++D + I
Sbjct: 434 TTGANVNETDDWGRTALHYAA-ASDMDRNKTI 464
Score = 63.3 bits (147), Expect = 2e-09
Identities = 44/168 (26%), Positives = 80/168 (47%), Gaps = 5/168 (2%)
Query: 136 DYRTRDGS--TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
D T D T +H A E ++ L+ GA N KD LTPL+ +V ++++ + +
Sbjct: 8 DVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRSEEAV-Q 66
Query: 194 TLLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVN 252
L+ A + A D + WQ +H A N V+ + ++ + +N + G T LH A+N
Sbjct: 67 VLIKHSADVNARD-KNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRGGRTALHHAALN 125
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
LL +G + A + ++ A G+LD+ ++ N+ ++
Sbjct: 126 GHVEMVNLLLAKGANINAFDKKDRRALHWAAYMGHLDVVALLINHGAE 173
Score = 41.9 bits (94), Expect = 0.005
Identities = 31/113 (27%), Positives = 48/113 (42%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
L+H + D + +H A G + ++ L+ GA +NA++ TPLH +
Sbjct: 2 LIHKTEDVNTLDSEKRTPLHVAAFLGDAEIIELLILSGARVNAKDNMWLTPLHRAVASRS 61
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRG 307
+ + L+ D A + QTP VA + AEVI S V RG
Sbjct: 62 EEAVQVLIKHSADVNARDKNWQTPLHVAAANKAVKCAEVIIPLLSSVNVSDRG 114
>BC100877-1|AAI00878.1| 241|Homo sapiens ASB15 protein protein.
Length = 241
Score = 75.8 bits (178), Expect = 4e-13
Identities = 46/138 (33%), Positives = 73/138 (52%), Gaps = 1/138 (0%)
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L +++T DG T + AV+ +E V+TLLE G PN K+ KG TPL ++V K +
Sbjct: 103 LWEFKTCDGETPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLIAV-KKGSYDMVS 161
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
TL+ + ++ ++ W +H+A + G V LL +G +++ R+ G TPL V A
Sbjct: 162 TLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLGVAAEYG 221
Query: 254 QDSCARQLLFRGCDKEAL 271
L+ +G D AL
Sbjct: 222 HCDVLEHLIHKGGDVLAL 239
Score = 47.2 bits (107), Expect = 1e-04
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V G ++ + KG+ PN + GETPL IA K ++ L+ LD
Sbjct: 119 VKAGLVENVRTLLEKGVWPNTK-NDKGETPLLIAVK-KGSYDMVSTLIKHNTSLDQPCVK 176
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPL 179
+AMH A ++ + V LL+ G + + +DG G+TPL
Sbjct: 177 RWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPL 214
Score = 33.1 bits (72), Expect = 2.5
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 2/91 (2%)
Query: 206 DLQGWQEVHQACRNGLVQHVDHLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D +GW +H+A + Q ++ +L Y + G TPL + R LL
Sbjct: 73 DEKGWFPLHEAVVQPIQQILEIVLDASYKTLWEFKTCDGETPLTLAVKAGLVENVRTLLE 132
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+G N +TP +AV G+ D+ +
Sbjct: 133 KGVWPNTKNDKGETPLLIAVKKGSYDMVSTL 163
>BC100876-1|AAI00877.1| 241|Homo sapiens ASB15 protein protein.
Length = 241
Score = 75.8 bits (178), Expect = 4e-13
Identities = 46/138 (33%), Positives = 73/138 (52%), Gaps = 1/138 (0%)
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L +++T DG T + AV+ +E V+TLLE G PN K+ KG TPL ++V K +
Sbjct: 103 LWEFKTCDGETPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLIAV-KKGSYDMVS 161
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
TL+ + ++ ++ W +H+A + G V LL +G +++ R+ G TPL V A
Sbjct: 162 TLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLGVAAEYG 221
Query: 254 QDSCARQLLFRGCDKEAL 271
L+ +G D AL
Sbjct: 222 HCDVLEHLIHKGGDVLAL 239
Score = 47.2 bits (107), Expect = 1e-04
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V G ++ + KG+ PN + GETPL IA K ++ L+ LD
Sbjct: 119 VKAGLVENVRTLLEKGVWPNTK-NDKGETPLLIAVK-KGSYDMVSTLIKHNTSLDQPCVK 176
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPL 179
+AMH A ++ + V LL+ G + + +DG G+TPL
Sbjct: 177 RWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPL 214
Score = 33.1 bits (72), Expect = 2.5
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 2/91 (2%)
Query: 206 DLQGWQEVHQACRNGLVQHVDHLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D +GW +H+A + Q ++ +L Y + G TPL + R LL
Sbjct: 73 DEKGWFPLHEAVVQPIQQILEIVLDASYKTLWEFKTCDGETPLTLAVKAGLVENVRTLLE 132
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+G N +TP +AV G+ D+ +
Sbjct: 133 KGVWPNTKNDKGETPLLIAVKKGSYDMVSTL 163
>BC100875-1|AAI00876.1| 241|Homo sapiens ASB15 protein protein.
Length = 241
Score = 75.8 bits (178), Expect = 4e-13
Identities = 46/138 (33%), Positives = 73/138 (52%), Gaps = 1/138 (0%)
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L +++T DG T + AV+ +E V+TLLE G PN K+ KG TPL ++V K +
Sbjct: 103 LWEFKTCDGETPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLIAV-KKGSYDMVS 161
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
TL+ + ++ ++ W +H+A + G V LL +G +++ R+ G TPL V A
Sbjct: 162 TLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLGVAAEYG 221
Query: 254 QDSCARQLLFRGCDKEAL 271
L+ +G D AL
Sbjct: 222 HCDVLEHLIHKGGDVLAL 239
Score = 47.2 bits (107), Expect = 1e-04
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V G ++ + KG+ PN + GETPL IA K ++ L+ LD
Sbjct: 119 VKAGLVENVRTLLEKGVWPNTK-NDKGETPLLIAVK-KGSYDMVSTLIKHNTSLDQPCVK 176
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPL 179
+AMH A ++ + V LL+ G + + +DG G+TPL
Sbjct: 177 RWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPL 214
Score = 33.1 bits (72), Expect = 2.5
Identities = 23/91 (25%), Positives = 38/91 (41%), Gaps = 2/91 (2%)
Query: 206 DLQGWQEVHQACRNGLVQHVDHLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
D +GW +H+A + Q ++ +L Y + G TPL + R LL
Sbjct: 73 DEKGWFPLHEAVVQPIQQILEIVLDASYKTLWEFKTCDGETPLTLAVKAGLVENVRTLLE 132
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+G N +TP +AV G+ D+ +
Sbjct: 133 KGVWPNTKNDKGETPLLIAVKKGSYDMVSTL 163
>BC100874-1|AAI00875.1| 241|Homo sapiens ASB15 protein protein.
Length = 241
Score = 75.8 bits (178), Expect = 4e-13
Identities = 46/138 (33%), Positives = 73/138 (52%), Gaps = 1/138 (0%)
Query: 134 LLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L +++T DG T + AV+ +E V+TLLE G PN K+ KG TPL ++V K +
Sbjct: 103 LWEFKTCDGETPLTLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLIAV-KKGSYDMVS 161
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
TL+ + ++ ++ W +H+A + G V LL +G +++ R+ G TPL V A
Sbjct: 162 TLIKHNTSLDQPCVKRWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPLGVAAEYG 221
Query: 254 QDSCARQLLFRGCDKEAL 271
L+ +G D AL
Sbjct: 222 HCDVLEHLIHKGGDVLAL 239
Score = 47.2 bits (107), Expect = 1e-04
Identities = 31/98 (31%), Positives = 48/98 (48%), Gaps = 2/98 (2%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V G ++ + KG+ PN + GETPL IA K ++ L+ LD
Sbjct: 119 VKAGLVENVRTLLEKGVWPNTK-NDKGETPLLIAVK-KGSYDMVSTLIKHNTSLDQPCVK 176
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPL 179
+AMH A ++ + V LL+ G + + +DG G+TPL
Sbjct: 177 RWSAMHEAAKQGRKDIVALLLKHGGNVHLRDGFGVTPL 214
Score = 33.9 bits (74), Expect = 1.4
Identities = 27/108 (25%), Positives = 46/108 (42%), Gaps = 3/108 (2%)
Query: 189 PLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLL--FYGADMNARNASGNTPL 246
P L E + + +A + D +GW +H+A + Q ++ +L Y + G TPL
Sbjct: 57 PELQEYVKYKYA-MDEADEKGWFPLHEAVVQPIQQILEIVLDASYKTLWEFKTCDGETPL 115
Query: 247 HVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ R LL +G N +TP +AV G+ D+ +
Sbjct: 116 TLAVKAGLVENVRTLLEKGVWPNTKNDKGETPLLIAVKKGSYDMVSTL 163
>AK027424-1|BAB55102.1| 784|Homo sapiens protein ( Homo sapiens
cDNA FLJ14518 fis, clone NT2RM1000850, weakly similar to
ANKYRIN R. ).
Length = 784
Score = 75.8 bits (178), Expect = 4e-13
Identities = 48/160 (30%), Positives = 76/160 (47%), Gaps = 1/160 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D G++ +H AVE E K LL A+PN + +G TPL+++V + ++ E
Sbjct: 431 VDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVV-ER 489
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL ++ A D W +H A +NG LL A +N + G TP+HV + Q
Sbjct: 490 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGLTPMHVACQHGQ 549
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
++ R LL RG D P A G+L + +++
Sbjct: 550 ENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLL 589
Score = 64.1 bits (149), Expect = 1e-09
Identities = 46/168 (27%), Positives = 72/168 (42%), Gaps = 2/168 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
+G T MH A + V+ LL G + + PL+ + P++
Sbjct: 536 EGLTPMHVACQHGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
++ A L G +H A + G + L+ +D+N + TPLHV A S AR
Sbjct: 596 SVNAQTLDGRTPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTARL 655
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRGP 308
LL RG KEA+ T +A G+L +++ K+D + RGP
Sbjct: 656 LLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLA--RGP 701
Score = 56.8 bits (131), Expect = 2e-07
Identities = 46/180 (25%), Positives = 77/180 (42%), Gaps = 4/180 (2%)
Query: 84 HGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGS 143
HGQ + + +G+D + ++ PL AA + + G ++ +T DG
Sbjct: 547 HGQENIVRILLRRGVDVSLQGKDAW-LPLHYAAWQGHLPIVKLLAKQPGVSVNAQTLDGR 605
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLLHDHATI 202
T +H A ++ + L++L + N TPL+++ T T LLH A
Sbjct: 606 TPLHLAAQRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTST--ARLLLHRGAGK 663
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
A G+ +H A RNG + V L+ AD+ AR T LH+ A + +L+
Sbjct: 664 EAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHGHSEVVEELV 723
Score = 49.2 bits (112), Expect = 4e-05
Identities = 47/186 (25%), Positives = 75/186 (40%), Gaps = 3/186 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLEL-GA 166
G TP+ +A I+ L+ G + + +D +H A + L VK L + G
Sbjct: 537 GLTPMHVACQ-HGQENIVRILLRRGVDVSLQGKDAWLPLHYAAWQGHLPIVKLLAKQPGV 595
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVD 226
S N + G TPL+L+ + + L+ + + L +H A G
Sbjct: 596 SVNAQTLDGRTPLHLAA-QRGHYRVARILIDLCSDVNVCSLLAQTPLHVAAETGHTSTAR 654
Query: 227 HLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAG 286
LL GA A + G T LH+ A N + + L+ D A NQT +A G
Sbjct: 655 LLLHRGAGKEAVTSDGYTALHLAARNGHLATVKLLVEEKADVLARGPLNQTALHLAAAHG 714
Query: 287 NLDLAE 292
+ ++ E
Sbjct: 715 HSEVVE 720
>BC107759-1|AAI07760.1| 360|Homo sapiens ankyrin repeat domain 2
(stretch responsive muscle) protein.
Length = 360
Score = 75.4 bits (177), Expect = 5e-13
Identities = 57/169 (33%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL+ G++ I K A G + C + T L A L+ +IL L++ GA +D+
Sbjct: 152 FLKAAVEGKMKVIEKFLADGGSADT-CDQFRRTALH-RASLEGHMEILEKLLDNGATVDF 209
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLL 196
+ R TAMH A LE VK L GA N +D TPL+++V T + + + E L
Sbjct: 210 QDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVE--IVEHFL 267
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
I A D +G +H A R + + LL +GADM +N +G TP
Sbjct: 268 SLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 316
Score = 64.5 bits (150), Expect = 9e-10
Identities = 46/166 (27%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A ++ K++ + G D + TA+HRA + +E ++ LL+ GA+ +++D
Sbjct: 153 LKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDR 212
Query: 174 KGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T ++ + + L LL H A D +H A R G V+ V+H L G
Sbjct: 213 LDCTAMHWAC--RGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG 270
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
++NAR+ G+T LH + + LL G D N A +TP
Sbjct: 271 LEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 316
Score = 49.6 bits (113), Expect = 3e-05
Identities = 43/160 (26%), Positives = 68/160 (42%), Gaps = 2/160 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
D T + AVE ++ ++ L G S + D T L+ + +L E LL + A
Sbjct: 148 DEETFLKAAVE-GKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEIL-EKLLDNGA 205
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
T+ D +H ACR G ++ V L +GAD N R+ +TPLHV Q
Sbjct: 206 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 265
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L G + A + T AV + +++ + +D
Sbjct: 266 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGAD 305
>AL359388-4|CAI14194.1| 333|Homo sapiens ankyrin repeat domain 2
(stretch responsive muscle) protein.
Length = 333
Score = 75.4 bits (177), Expect = 5e-13
Identities = 57/169 (33%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL+ G++ I K A G + C + T L A L+ +IL L++ GA +D+
Sbjct: 125 FLKAAVEGKMKVIEKFLADGGSADT-CDQFRRTALH-RASLEGHMEILEKLLDNGATVDF 182
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLL 196
+ R TAMH A LE VK L GA N +D TPL+++V T + + + E L
Sbjct: 183 QDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVE--IVEHFL 240
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
I A D +G +H A R + + LL +GADM +N +G TP
Sbjct: 241 SLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 289
Score = 64.5 bits (150), Expect = 9e-10
Identities = 46/166 (27%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A ++ K++ + G D + TA+HRA + +E ++ LL+ GA+ +++D
Sbjct: 126 LKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDR 185
Query: 174 KGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T ++ + + L LL H A D +H A R G V+ V+H L G
Sbjct: 186 LDCTAMHWAC--RGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG 243
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
++NAR+ G+T LH + + LL G D N A +TP
Sbjct: 244 LEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 289
Score = 49.6 bits (113), Expect = 3e-05
Identities = 43/160 (26%), Positives = 68/160 (42%), Gaps = 2/160 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
D T + AVE ++ ++ L G S + D T L+ + +L E LL + A
Sbjct: 121 DEETFLKAAVE-GKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEIL-EKLLDNGA 178
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
T+ D +H ACR G ++ V L +GAD N R+ +TPLHV Q
Sbjct: 179 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 238
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L G + A + T AV + +++ + +D
Sbjct: 239 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGAD 278
>AL355315-9|CAI15463.1| 333|Homo sapiens ankyrin repeat domain 2
(stretch responsive muscle) protein.
Length = 333
Score = 75.4 bits (177), Expect = 5e-13
Identities = 57/169 (33%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL+ G++ I K A G + C + T L A L+ +IL L++ GA +D+
Sbjct: 125 FLKAAVEGKMKVIEKFLADGGSADT-CDQFRRTALH-RASLEGHMEILEKLLDNGATVDF 182
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLL 196
+ R TAMH A LE VK L GA N +D TPL+++V T + + + E L
Sbjct: 183 QDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVE--IVEHFL 240
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
I A D +G +H A R + + LL +GADM +N +G TP
Sbjct: 241 SLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 289
Score = 64.5 bits (150), Expect = 9e-10
Identities = 46/166 (27%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A ++ K++ + G D + TA+HRA + +E ++ LL+ GA+ +++D
Sbjct: 126 LKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDR 185
Query: 174 KGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T ++ + + L LL H A D +H A R G V+ V+H L G
Sbjct: 186 LDCTAMHWAC--RGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG 243
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
++NAR+ G+T LH + + LL G D N A +TP
Sbjct: 244 LEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 289
Score = 49.6 bits (113), Expect = 3e-05
Identities = 43/160 (26%), Positives = 68/160 (42%), Gaps = 2/160 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
D T + AVE ++ ++ L G S + D T L+ + +L E LL + A
Sbjct: 121 DEETFLKAAVE-GKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEIL-EKLLDNGA 178
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
T+ D +H ACR G ++ V L +GAD N R+ +TPLHV Q
Sbjct: 179 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 238
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L G + A + T AV + +++ + +D
Sbjct: 239 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGAD 278
>AJ583444-1|CAE47432.1| 449|Homo sapiens ankyrin repeat protein
protein.
Length = 449
Score = 75.4 bits (177), Expect = 5e-13
Identities = 57/169 (33%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL+ G++ I K A G + C + T L A L+ +IL L++ GA +D+
Sbjct: 241 FLKAAVEGKMKVIEKFLADGGSADT-CDQFRRTALH-RASLEGHMEILEKLLDNGATVDF 298
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLL 196
+ R TAMH A LE VK L GA N +D TPL+++V T + + + E L
Sbjct: 299 QDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVE--IVEHFL 356
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
I A D +G +H A R + + LL +GADM +N +G TP
Sbjct: 357 SLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 405
Score = 64.5 bits (150), Expect = 9e-10
Identities = 46/166 (27%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A ++ K++ + G D + TA+HRA + +E ++ LL+ GA+ +++D
Sbjct: 242 LKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDR 301
Query: 174 KGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T ++ + + L LL H A D +H A R G V+ V+H L G
Sbjct: 302 LDCTAMHWAC--RGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG 359
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
++NAR+ G+T LH + + LL G D N A +TP
Sbjct: 360 LEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 405
Score = 49.6 bits (113), Expect = 3e-05
Identities = 43/160 (26%), Positives = 68/160 (42%), Gaps = 2/160 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
D T + AVE ++ ++ L G S + D T L+ + +L E LL + A
Sbjct: 237 DEETFLKAAVE-GKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEIL-EKLLDNGA 294
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
T+ D +H ACR G ++ V L +GAD N R+ +TPLHV Q
Sbjct: 295 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 354
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L G + A + T AV + +++ + +D
Sbjct: 355 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGAD 394
>AJ304805-1|CAC19412.1| 333|Homo sapiens skeletal muscle ankyrin
protein 2 protein.
Length = 333
Score = 75.4 bits (177), Expect = 5e-13
Identities = 57/169 (33%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL+ G++ I K A G + C + T L A L+ +IL L++ GA +D+
Sbjct: 125 FLKAAVEGKMKVIEKFLADGGSADT-CDQFRRTALH-RASLEGHMEILEKLLDNGATVDF 182
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLL 196
+ R TAMH A LE VK L GA N +D TPL+++V T + + + E L
Sbjct: 183 QDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVE--IVEHFL 240
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
I A D +G +H A R + + LL +GADM +N +G TP
Sbjct: 241 SLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 289
Score = 64.5 bits (150), Expect = 9e-10
Identities = 46/166 (27%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A ++ K++ + G D + TA+HRA + +E ++ LL+ GA+ +++D
Sbjct: 126 LKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDR 185
Query: 174 KGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T ++ + + L LL H A D +H A R G V+ V+H L G
Sbjct: 186 LDCTAMHWAC--RGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG 243
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
++NAR+ G+T LH + + LL G D N A +TP
Sbjct: 244 LEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 289
Score = 49.6 bits (113), Expect = 3e-05
Identities = 43/160 (26%), Positives = 68/160 (42%), Gaps = 2/160 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
D T + AVE ++ ++ L G S + D T L+ + +L E LL + A
Sbjct: 121 DEETFLKAAVE-GKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEIL-EKLLDNGA 178
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
T+ D +H ACR G ++ V L +GAD N R+ +TPLHV Q
Sbjct: 179 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 238
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L G + A + T AV + +++ + +D
Sbjct: 239 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGAD 278
>AJ304804-1|CAC19411.1| 333|Homo sapiens skeletal muscle ankyrin
repeat protein.
Length = 333
Score = 75.4 bits (177), Expect = 5e-13
Identities = 57/169 (33%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL+ G++ I K A G + C + T L A L+ +IL L++ GA +D+
Sbjct: 125 FLKAAVEGKMKVIEKFLADGGSADT-CDQFRRTALH-RASLEGHMEILEKLLDNGATVDF 182
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLL 196
+ R TAMH A LE VK L GA N +D TPL+++V T + + + E L
Sbjct: 183 QDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVE--IVEHFL 240
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
I A D +G +H A R + + LL +GADM +N +G TP
Sbjct: 241 SLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 289
Score = 64.5 bits (150), Expect = 9e-10
Identities = 46/166 (27%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A ++ K++ + G D + TA+HRA + +E ++ LL+ GA+ +++D
Sbjct: 126 LKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDR 185
Query: 174 KGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T ++ + + L LL H A D +H A R G V+ V+H L G
Sbjct: 186 LDCTAMHWAC--RGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG 243
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
++NAR+ G+T LH + + LL G D N A +TP
Sbjct: 244 LEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 289
Score = 49.6 bits (113), Expect = 3e-05
Identities = 43/160 (26%), Positives = 68/160 (42%), Gaps = 2/160 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
D T + AVE ++ ++ L G S + D T L+ + +L E LL + A
Sbjct: 121 DEETFLKAAVE-GKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEIL-EKLLDNGA 178
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
T+ D +H ACR G ++ V L +GAD N R+ +TPLHV Q
Sbjct: 179 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 238
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L G + A + T AV + +++ + +D
Sbjct: 239 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGAD 278
>AB058599-1|BAB60958.1| 333|Homo sapiens ankyrin-repeat protein
protein.
Length = 333
Score = 75.4 bits (177), Expect = 5e-13
Identities = 57/169 (33%), Positives = 83/169 (49%), Gaps = 5/169 (2%)
Query: 78 FLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY 137
FL+ G++ I K A G + C + T L A L+ +IL L++ GA +D+
Sbjct: 125 FLKAAVEGKMKVIEKFLADGGSADT-CDQFRRTALH-RASLEGHMEILEKLLDNGATVDF 182
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV-TNKTDPLLCETLL 196
+ R TAMH A LE VK L GA N +D TPL+++V T + + + E L
Sbjct: 183 QDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVE--IVEHFL 240
Query: 197 HDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
I A D +G +H A R + + LL +GADM +N +G TP
Sbjct: 241 SLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 289
Score = 64.5 bits (150), Expect = 9e-10
Identities = 46/166 (27%), Positives = 77/166 (46%), Gaps = 3/166 (1%)
Query: 114 IAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDG 173
+ A ++ K++ + G D + TA+HRA + +E ++ LL+ GA+ +++D
Sbjct: 126 LKAAVEGKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEILEKLLDNGATVDFQDR 185
Query: 174 KGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
T ++ + + L LL H A D +H A R G V+ V+H L G
Sbjct: 186 LDCTAMHWAC--RGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEHFLSLG 243
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
++NAR+ G+T LH + + LL G D N A +TP
Sbjct: 244 LEINARDREGDTALHDAVRLNRYKIIKLLLLHGADMMTKNLAGKTP 289
Score = 49.6 bits (113), Expect = 3e-05
Identities = 43/160 (26%), Positives = 68/160 (42%), Gaps = 2/160 (1%)
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
D T + AVE ++ ++ L G S + D T L+ + +L E LL + A
Sbjct: 121 DEETFLKAAVE-GKMKVIEKFLADGGSADTCDQFRRTALHRASLEGHMEIL-EKLLDNGA 178
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
T+ D +H ACR G ++ V L +GAD N R+ +TPLHV Q
Sbjct: 179 TVDFQDRLDCTAMHWACRGGHLEVVKLLQSHGADTNVRDKLLSTPLHVAVRTGQVEIVEH 238
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L G + A + T AV + +++ + +D
Sbjct: 239 FLSLGLEINARDREGDTALHDAVRLNRYKIIKLLLLHGAD 278
>AF308292-1|AAG48260.1| 352|Homo sapiens serologically defined
breast cancer antigen NY-BR-49 protein.
Length = 352
Score = 74.5 bits (175), Expect = 8e-13
Identities = 44/133 (33%), Positives = 67/133 (50%), Gaps = 1/133 (0%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+D G++ +H AVE E K LL A+PN + +G TPL+++V + ++ E
Sbjct: 118 VDLALDSGASLLHLAVEAGQEECAKWLLLNNANPNLSNRRGSTPLHMAVERRVRGVV-EL 176
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL ++ A D W +H A +NG LL A +N + G TP+HV + Q
Sbjct: 177 LLARKISVNAKDEDQWTALHFAAQNGDESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQ 236
Query: 255 DSCARQLLFRGCD 267
++ R LL RG D
Sbjct: 237 ENIVRILLRRGVD 249
Score = 52.8 bits (121), Expect = 3e-06
Identities = 42/125 (33%), Positives = 59/125 (47%), Gaps = 4/125 (3%)
Query: 112 LTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYK 171
L + AG + AK L+ L N L R GST +H AVE+ V+ LL S N K
Sbjct: 131 LAVEAGQEECAKWLL-LNNANPNLS--NRRGSTPLHMAVERRVRGVVELLLARKISVNAK 187
Query: 172 DGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFY 231
D T L+ + N D LL +A++ D +G +H AC++G V LL
Sbjct: 188 DEDQWTALHFAAQNG-DESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRILLRR 246
Query: 232 GADMN 236
G D++
Sbjct: 247 GVDVS 251
Score = 40.3 bits (90), Expect = 0.016
Identities = 26/100 (26%), Positives = 46/100 (46%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
LL ++A ++ +G +H A + V+ LL +NA++ T LH A N
Sbjct: 144 LLLNNANPNLSNRRGSTPLHMAVERRVRGVVELLLARKISVNAKDEDQWTALHFAAQNGD 203
Query: 255 DSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+S R LL + ++F +TP VA G ++ ++
Sbjct: 204 ESSTRLLLEKNASVNEVDFEGRTPMHVACQHGQENIVRIL 243
>AL590402-2|CAH74024.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 73.3 bits (172), Expect = 2e-12
Identities = 61/200 (30%), Positives = 90/200 (45%), Gaps = 11/200 (5%)
Query: 99 DPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
D N+ + L IAA S + L+ L+ GA +Y+ G T +H A + +
Sbjct: 56 DVNYAFGRVKRSLLHIAANCGS-VECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCM 114
Query: 159 KTLLELGASPNYKDGKGLTPL-YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQAC 217
LLE A N + +GLT + +L+V +T+ L L+ + + D G +H AC
Sbjct: 115 SKLLEYSADVNICNNEGLTAIHWLAVNGRTE--LLHDLVQHVSDVDVEDAMGQTALHVAC 172
Query: 218 RNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQT 277
V LL GAD+N N SG TPL+ + Q A+ LL RG K + T
Sbjct: 173 T------VQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVT 225
Query: 278 PYQVAVIAGNLDLAEVIKNY 297
P + V G + EV+ Y
Sbjct: 226 PLDLCVQGGYGETCEVLIQY 245
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/88 (31%), Positives = 40/88 (45%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A G V+ + LL GA+ N ++ SG TPLH+ A N Q C +LL D N
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNYKSD 300
T + G +L + + SD
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSD 156
>AL513472-2|CAH71890.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 73.3 bits (172), Expect = 2e-12
Identities = 61/200 (30%), Positives = 90/200 (45%), Gaps = 11/200 (5%)
Query: 99 DPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
D N+ + L IAA S + L+ L+ GA +Y+ G T +H A + +
Sbjct: 56 DVNYAFGRVKRSLLHIAANCGS-VECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCM 114
Query: 159 KTLLELGASPNYKDGKGLTPL-YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQAC 217
LLE A N + +GLT + +L+V +T+ L L+ + + D G +H AC
Sbjct: 115 SKLLEYSADVNICNNEGLTAIHWLAVNGRTE--LLHDLVQHVSDVDVEDAMGQTALHVAC 172
Query: 218 RNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQT 277
V LL GAD+N N SG TPL+ + Q A+ LL RG K + T
Sbjct: 173 T------VQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVT 225
Query: 278 PYQVAVIAGNLDLAEVIKNY 297
P + V G + EV+ Y
Sbjct: 226 PLDLCVQGGYGETCEVLIQY 245
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/88 (31%), Positives = 40/88 (45%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A G V+ + LL GA+ N ++ SG TPLH+ A N Q C +LL D N
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNYKSD 300
T + G +L + + SD
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSD 156
>AL357315-1|CAI16815.1| 903|Homo sapiens HECT domain and ankyrin
repeat containing, E3 ubiquitin protein ligase 1
protein.
Length = 903
Score = 73.3 bits (172), Expect = 2e-12
Identities = 61/200 (30%), Positives = 90/200 (45%), Gaps = 11/200 (5%)
Query: 99 DPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAV 158
D N+ + L IAA S + L+ L+ GA +Y+ G T +H A + +
Sbjct: 56 DVNYAFGRVKRSLLHIAANCGS-VECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCM 114
Query: 159 KTLLELGASPNYKDGKGLTPL-YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQAC 217
LLE A N + +GLT + +L+V +T+ L L+ + + D G +H AC
Sbjct: 115 SKLLEYSADVNICNNEGLTAIHWLAVNGRTE--LLHDLVQHVSDVDVEDAMGQTALHVAC 172
Query: 218 RNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQT 277
V LL GAD+N N SG TPL+ + Q A+ LL RG K + T
Sbjct: 173 T------VQCLLDSGADINRPNVSGATPLYFACSHGQRDTAQILLLRGA-KYLPDKNGVT 225
Query: 278 PYQVAVIAGNLDLAEVIKNY 297
P + V G + EV+ Y
Sbjct: 226 PLDLCVQGGYGETCEVLIQY 245
Score = 44.0 bits (99), Expect = 0.001
Identities = 28/88 (31%), Positives = 40/88 (45%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A G V+ + LL GA+ N ++ SG TPLH+ A N Q C +LL D N
Sbjct: 69 LHIAANCGSVECLVLLLKKGANPNYQDISGCTPLHLAARNGQKKCMSKLLEYSADVNICN 128
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNYKSD 300
T + G +L + + SD
Sbjct: 129 NEGLTAIHWLAVNGRTELLHDLVQHVSD 156
>AF159164-1|AAD45345.1| 544|Homo sapiens ankyrin repeat-containing
protein ASB-2 protein.
Length = 544
Score = 72.1 bits (169), Expect = 4e-12
Identities = 78/298 (26%), Positives = 128/298 (42%), Gaps = 19/298 (6%)
Query: 24 KAGKFLDEERRLGDYPFNGPVGYLE---LKYKRRVYKMLKLDEKTLKALHSRANLRRFLE 80
K GK L E + G P + Y + LK +R Y +D++TL+ +L
Sbjct: 37 KEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGT-IDQRTLQE-----ETAVYLA 90
Query: 81 HVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR 140
G +D + G +P+ ++ ETPL A K+ + I LV A ++R
Sbjct: 91 -TCRGHLDCLLSLLQAGAEPDIS-NKSRETPLYKACERKNAEAVKI-LVQHNADTNHRCN 147
Query: 141 DGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHA 200
G TA+H +V +N LE ++ L+ GA K+ G TPL+++ + L L A
Sbjct: 148 RGWTALHESVSRNDLEVMQILVSGGAKVESKNAYG-TPLFVAAQSGQLEAL-RFLAKYGA 205
Query: 201 TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQ 260
I +++AC+N + V+ LL GAD N N G PLH+ + Q
Sbjct: 206 DINTQASDNASALYEACKNEHEEVVEFLLSQGADANKTNKDGLLPLHIASKKGNYRIV-Q 264
Query: 261 LLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVPFRGPPR---YNPRR 315
+L + + + +P +A + ++ E + + + D P P R Y RR
Sbjct: 265 MLLPVTSRTRIRRSGVSPLHLAAERNHDEVLEALLSARFDVNTPL-APERARLYEDRR 321
Score = 36.7 bits (81), Expect = 0.20
Identities = 24/124 (19%), Positives = 53/124 (42%), Gaps = 2/124 (1%)
Query: 178 PLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL-LFYGADMN 236
PL ++ + + L +T++ + + + +GW +H+A G V + L Y ++
Sbjct: 19 PLIKAIKDGDEEAL-KTMIKEGKNLAEPNKEGWLPLHEAAYYGQVGCLKVLQRAYPGTID 77
Query: 237 ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
R T +++ C LL G + + N + +TP A N + +++
Sbjct: 78 QRTLQEETAVYLATCRGHLDCLLSLLQAGAEPDISNKSRETPLYKACERKNAEAVKILVQ 137
Query: 297 YKSD 300
+ +D
Sbjct: 138 HNAD 141
>M73980-1|AAA60614.1| 2444|Homo sapiens TAN1 protein.
Length = 2444
Score = 71.7 bits (168), Expect = 6e-12
Identities = 55/180 (30%), Positives = 90/180 (50%), Gaps = 4/180 (2%)
Query: 120 SPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPL 179
+PA I + G +L + R G TA+H A + +A K LLE A N +D G TPL
Sbjct: 1907 APAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPL 1966
Query: 180 YLSVTNKTDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
+ +V+ + + L+ + AT + A G + A R + ++ L+ AD+NA
Sbjct: 1967 HAAVSADAQGVF-QILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAV 2025
Query: 239 NASGNTPLH-VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
+ G + LH AVN D+ A LL G +K+ N +TP +A G+ + A+V+ ++
Sbjct: 2026 DDLGKSALHWAAAVNNVDA-AVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDH 2084
Score = 56.8 bits (131), Expect = 2e-07
Identities = 54/213 (25%), Positives = 94/213 (44%), Gaps = 8/213 (3%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
TGET L +AA S + L+ A + + G T +H AV ++ + L+ A
Sbjct: 1928 TGETALHLAARY-SRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRNRA 1986
Query: 167 SP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ + + G TPL L+ + +L E L++ HA + A D G +H A V
Sbjct: 1987 TDLDARMHDGTTPLILAARLAVEGML-EDLINSHADVNAVDDLGKSALHWAAAVNNVDAA 2045
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA+ + +N TPL + A A+ LL +++ + ++ P +A
Sbjct: 2046 VVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQER 2105
Query: 286 GNLDLAEVIKNY---KSDEI--VPFRGPPRYNP 313
+ D+ ++ Y +S ++ P G P +P
Sbjct: 2106 MHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSP 2138
Score = 32.7 bits (71), Expect = 3.3
Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 225 VDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ ++ GA + N + +G T LH+ A ++ A++LL D + +TP AV
Sbjct: 1911 ISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAV 1970
Query: 284 IAGNLDLAEV-IKNYKSD 300
A + ++ I+N +D
Sbjct: 1971 SADAQGVFQILIRNRATD 1988
>AL592301-5|CAI13934.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 71.7 bits (168), Expect = 6e-12
Identities = 55/180 (30%), Positives = 90/180 (50%), Gaps = 4/180 (2%)
Query: 120 SPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPL 179
+PA I + G +L + R G TA+H A + +A K LLE A N +D G TPL
Sbjct: 1906 APAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPL 1965
Query: 180 YLSVTNKTDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
+ +V+ + + L+ + AT + A G + A R + ++ L+ AD+NA
Sbjct: 1966 HAAVSADAQGVF-QILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAV 2024
Query: 239 NASGNTPLH-VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
+ G + LH AVN D+ A LL G +K+ N +TP +A G+ + A+V+ ++
Sbjct: 2025 DDLGKSALHWAAAVNNVDA-AVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDH 2083
Score = 56.8 bits (131), Expect = 2e-07
Identities = 54/213 (25%), Positives = 94/213 (44%), Gaps = 8/213 (3%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
TGET L +AA S + L+ A + + G T +H AV ++ + L+ A
Sbjct: 1927 TGETALHLAARY-SRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRNRA 1985
Query: 167 SP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ + + G TPL L+ + +L E L++ HA + A D G +H A V
Sbjct: 1986 TDLDARMHDGTTPLILAARLAVEGML-EDLINSHADVNAVDDLGKSALHWAAAVNNVDAA 2044
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA+ + +N TPL + A A+ LL +++ + ++ P +A
Sbjct: 2045 VVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQER 2104
Query: 286 GNLDLAEVIKNY---KSDEI--VPFRGPPRYNP 313
+ D+ ++ Y +S ++ P G P +P
Sbjct: 2105 MHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSP 2137
Score = 32.7 bits (71), Expect = 3.3
Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 225 VDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ ++ GA + N + +G T LH+ A ++ A++LL D + +TP AV
Sbjct: 1910 ISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAV 1969
Query: 284 IAGNLDLAEV-IKNYKSD 300
A + ++ I+N +D
Sbjct: 1970 SADAQGVFQILIRNRATD 1987
>AL354671-1|CAI16149.1| 2555|Homo sapiens Notch homolog 1,
translocation-associated (Drosophila) protein.
Length = 2555
Score = 71.7 bits (168), Expect = 6e-12
Identities = 55/180 (30%), Positives = 90/180 (50%), Gaps = 4/180 (2%)
Query: 120 SPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPL 179
+PA I + G +L + R G TA+H A + +A K LLE A N +D G TPL
Sbjct: 1906 APAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPL 1965
Query: 180 YLSVTNKTDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
+ +V+ + + L+ + AT + A G + A R + ++ L+ AD+NA
Sbjct: 1966 HAAVSADAQGVF-QILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAV 2024
Query: 239 NASGNTPLH-VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
+ G + LH AVN D+ A LL G +K+ N +TP +A G+ + A+V+ ++
Sbjct: 2025 DDLGKSALHWAAAVNNVDA-AVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDH 2083
Score = 56.8 bits (131), Expect = 2e-07
Identities = 54/213 (25%), Positives = 94/213 (44%), Gaps = 8/213 (3%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
TGET L +AA S + L+ A + + G T +H AV ++ + L+ A
Sbjct: 1927 TGETALHLAARY-SRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRNRA 1985
Query: 167 SP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ + + G TPL L+ + +L E L++ HA + A D G +H A V
Sbjct: 1986 TDLDARMHDGTTPLILAARLAVEGML-EDLINSHADVNAVDDLGKSALHWAAAVNNVDAA 2044
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA+ + +N TPL + A A+ LL +++ + ++ P +A
Sbjct: 2045 VVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQER 2104
Query: 286 GNLDLAEVIKNY---KSDEI--VPFRGPPRYNP 313
+ D+ ++ Y +S ++ P G P +P
Sbjct: 2105 MHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSP 2137
Score = 32.7 bits (71), Expect = 3.3
Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 225 VDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ ++ GA + N + +G T LH+ A ++ A++LL D + +TP AV
Sbjct: 1910 ISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAV 1969
Query: 284 IAGNLDLAEV-IKNYKSD 300
A + ++ I+N +D
Sbjct: 1970 SADAQGVFQILIRNRATD 1987
>AF308602-1|AAG33848.1| 2556|Homo sapiens NOTCH 1 protein.
Length = 2556
Score = 71.7 bits (168), Expect = 6e-12
Identities = 55/180 (30%), Positives = 90/180 (50%), Gaps = 4/180 (2%)
Query: 120 SPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPL 179
+PA I + G +L + R G TA+H A + +A K LLE A N +D G TPL
Sbjct: 1907 APAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPL 1966
Query: 180 YLSVTNKTDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
+ +V+ + + L+ + AT + A G + A R + ++ L+ AD+NA
Sbjct: 1967 HAAVSADAQGVF-QILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAV 2025
Query: 239 NASGNTPLH-VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
+ G + LH AVN D+ A LL G +K+ N +TP +A G+ + A+V+ ++
Sbjct: 2026 DDLGKSALHWAAAVNNVDA-AVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDH 2084
Score = 56.8 bits (131), Expect = 2e-07
Identities = 54/213 (25%), Positives = 94/213 (44%), Gaps = 8/213 (3%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
TGET L +AA S + L+ A + + G T +H AV ++ + L+ A
Sbjct: 1928 TGETALHLAARY-SRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRNRA 1986
Query: 167 SP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ + + G TPL L+ + +L E L++ HA + A D G +H A V
Sbjct: 1987 TDLDARMHDGTTPLILAARLAVEGML-EDLINSHADVNAVDDLGKSALHWAAAVNNVDAA 2045
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA+ + +N TPL + A A+ LL +++ + ++ P +A
Sbjct: 2046 VVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQER 2105
Query: 286 GNLDLAEVIKNY---KSDEI--VPFRGPPRYNP 313
+ D+ ++ Y +S ++ P G P +P
Sbjct: 2106 MHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSP 2138
Score = 32.7 bits (71), Expect = 3.3
Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 225 VDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ ++ GA + N + +G T LH+ A ++ A++LL D + +TP AV
Sbjct: 1911 ISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAV 1970
Query: 284 IAGNLDLAEV-IKNYKSD 300
A + ++ I+N +D
Sbjct: 1971 SADAQGVFQILIRNRATD 1988
>AB209873-1|BAD93110.1| 2067|Homo sapiens notch1 preproprotein variant
protein.
Length = 2067
Score = 71.7 bits (168), Expect = 6e-12
Identities = 55/180 (30%), Positives = 90/180 (50%), Gaps = 4/180 (2%)
Query: 120 SPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPL 179
+PA I + G +L + R G TA+H A + +A K LLE A N +D G TPL
Sbjct: 1418 APAVISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPL 1477
Query: 180 YLSVTNKTDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
+ +V+ + + L+ + AT + A G + A R + ++ L+ AD+NA
Sbjct: 1478 HAAVSADAQGVF-QILIRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAV 1536
Query: 239 NASGNTPLH-VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
+ G + LH AVN D+ A LL G +K+ N +TP +A G+ + A+V+ ++
Sbjct: 1537 DDLGKSALHWAAAVNNVDA-AVVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDH 1595
Score = 56.8 bits (131), Expect = 2e-07
Identities = 54/213 (25%), Positives = 94/213 (44%), Gaps = 8/213 (3%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
TGET L +AA S + L+ A + + G T +H AV ++ + L+ A
Sbjct: 1439 TGETALHLAARY-SRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQILIRNRA 1497
Query: 167 SP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHV 225
+ + + G TPL L+ + +L E L++ HA + A D G +H A V
Sbjct: 1498 TDLDARMHDGTTPLILAARLAVEGML-EDLINSHADVNAVDDLGKSALHWAAAVNNVDAA 1556
Query: 226 DHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
LL GA+ + +N TPL + A A+ LL +++ + ++ P +A
Sbjct: 1557 VVLLKNGANKDMQNNREETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDIAQER 1616
Query: 286 GNLDLAEVIKNY---KSDEI--VPFRGPPRYNP 313
+ D+ ++ Y +S ++ P G P +P
Sbjct: 1617 MHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSP 1649
Score = 32.7 bits (71), Expect = 3.3
Identities = 20/78 (25%), Positives = 38/78 (48%), Gaps = 2/78 (2%)
Query: 225 VDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ ++ GA + N + +G T LH+ A ++ A++LL D + +TP AV
Sbjct: 1422 ISDFIYQGASLHNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAV 1481
Query: 284 IAGNLDLAEV-IKNYKSD 300
A + ++ I+N +D
Sbjct: 1482 SADAQGVFQILIRNRATD 1499
>AL159174-2|CAI39610.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 71.3 bits (167), Expect = 8e-12
Identities = 56/195 (28%), Positives = 94/195 (48%), Gaps = 4/195 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
+I+ AL++ G LD + +DG+TA+H A ++ K L++ GA+ K+ G T L+L+
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
N + LL + + G +H A R + + LL ++ +N +G
Sbjct: 62 CQN-SHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEI 302
+T LHV A A+ LL G D +N A QTP + A N ++A ++ K+ ++
Sbjct: 121 DTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLT--KAPQV 178
Query: 303 VPF-RGPPRYNPRRR 316
+ F RG R R
Sbjct: 179 LRFSRGRSLRKKRER 193
>AL096678-3|CAI42281.1| 640|Homo sapiens ankyrin repeat domain 6
protein.
Length = 640
Score = 71.3 bits (167), Expect = 8e-12
Identities = 56/195 (28%), Positives = 94/195 (48%), Gaps = 4/195 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
+I+ AL++ G LD + +DG+TA+H A ++ K L++ GA+ K+ G T L+L+
Sbjct: 2 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLIKAGANVLAKNKAGNTALHLA 61
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
N + LL + + G +H A R + + LL ++ +N +G
Sbjct: 62 CQN-SHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 120
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEI 302
+T LHV A A+ LL G D +N A QTP + A N ++A ++ K+ ++
Sbjct: 121 DTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLT--KAPQV 178
Query: 303 VPF-RGPPRYNPRRR 316
+ F RG R R
Sbjct: 179 LRFSRGRSLRKKRER 193
>U97669-1|AAB91371.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 70.9 bits (166), Expect = 1e-11
Identities = 53/178 (29%), Positives = 86/178 (48%), Gaps = 3/178 (1%)
Query: 122 AKILIALVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLY 180
A I+ L+ GA L RT R G TA+H A +A K LL+ GA N +D G TPL+
Sbjct: 1818 ASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLH 1877
Query: 181 LSVTNKTDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN 239
+VT + + L+ + +T + A G + A R + V+ L+ AD+NA +
Sbjct: 1878 TAVTADAQGVF-QILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVD 1936
Query: 240 ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
G + LH A LL G +K+ + +TP +A G+ + A+++ ++
Sbjct: 1937 ELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDH 1994
Score = 53.2 bits (122), Expect = 2e-06
Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 3/194 (1%)
Query: 90 ITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRA 149
I+ +G TGET L +AA + A L++ GA + + G T +H A
Sbjct: 1821 ISDLICQGAQLGARTDRTGETALHLAARY-ARADAAKRLLDAGADTNAQDHSGRTPLHTA 1879
Query: 150 VEKNSLEAVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
V ++ + L+ ++ + + G T L L+ + ++ E L+ HA + A D
Sbjct: 1880 VTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMV-EELIASHADVNAVDEL 1938
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
G +H A V+ LL GA+ + +++ TPL + A A+ LL ++
Sbjct: 1939 GKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANR 1998
Query: 269 EALNFANQTPYQVA 282
E + ++ P VA
Sbjct: 1999 EITDHLDRLPRDVA 2012
Score = 41.5 bits (93), Expect = 0.007
Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 225 VDHLLFYGADMNAR-NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ L+ GA + AR + +G T LH+ A A+ A++LL G D A + + +TP AV
Sbjct: 1821 ISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAV 1880
Query: 284 IAGNLDLAEV-IKNYKSD 300
A + ++ I+N +D
Sbjct: 1881 TADAQGVFQILIRNRSTD 1898
>AL117504-1|CAB55968.1| 641|Homo sapiens hypothetical protein
protein.
Length = 641
Score = 70.9 bits (166), Expect = 1e-11
Identities = 56/195 (28%), Positives = 94/195 (48%), Gaps = 4/195 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
+I+ AL++ G LD + +DG+TA+H A ++ K L++ GA+ K+ G T L+L+
Sbjct: 3 EIIAALIHEGCALDRQDKDGNTALHEASWHGFSQSAKLLVKAGANVLAKNKAGNTALHLA 62
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
N + LL + + G +H A R + + LL ++ +N +G
Sbjct: 63 CQN-SHSQSTRVLLLAGSRADLKNNAGDTCLHVAARYNHLSIIRLLLTAFCSVHEKNQAG 121
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEI 302
+T LHV A A+ LL G D +N A QTP + A N ++A ++ K+ ++
Sbjct: 122 DTALHVAAALNHKKVAKILLEAGADTTIVNNAGQTPLETARYHNNPEVALLLT--KAPQV 179
Query: 303 VPF-RGPPRYNPRRR 316
+ F RG R R
Sbjct: 180 LRFSRGRSLRKKRER 194
>AF058900-1|AAC14346.1| 2321|Homo sapiens Notch3 protein.
Length = 2321
Score = 70.9 bits (166), Expect = 1e-11
Identities = 53/178 (29%), Positives = 86/178 (48%), Gaps = 3/178 (1%)
Query: 122 AKILIALVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLY 180
A I+ L+ GA L RT R G TA+H A +A K LL+ GA N +D G TPL+
Sbjct: 1818 ASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLH 1877
Query: 181 LSVTNKTDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN 239
+VT + + L+ + +T + A G + A R + V+ L+ AD+NA +
Sbjct: 1878 TAVTADAQGVF-QILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVD 1936
Query: 240 ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
G + LH A LL G +K+ + +TP +A G+ + A+++ ++
Sbjct: 1937 ELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDH 1994
Score = 53.2 bits (122), Expect = 2e-06
Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 3/194 (1%)
Query: 90 ITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRA 149
I+ +G TGET L +AA + A L++ GA + + G T +H A
Sbjct: 1821 ISDLICQGAQLGARTDRTGETALHLAARY-ARADAAKRLLDAGADTNAQDHSGRTPLHTA 1879
Query: 150 VEKNSLEAVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
V ++ + L+ ++ + + G T L L+ + ++ E L+ HA + A D
Sbjct: 1880 VTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMV-EELIASHADVNAVDEL 1938
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
G +H A V+ LL GA+ + +++ TPL + A A+ LL ++
Sbjct: 1939 GKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANR 1998
Query: 269 EALNFANQTPYQVA 282
E + ++ P VA
Sbjct: 1999 EITDHLDRLPRDVA 2012
Score = 41.5 bits (93), Expect = 0.007
Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 225 VDHLLFYGADMNAR-NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ L+ GA + AR + +G T LH+ A A+ A++LL G D A + + +TP AV
Sbjct: 1821 ISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAV 1880
Query: 284 IAGNLDLAEV-IKNYKSD 300
A + ++ I+N +D
Sbjct: 1881 TADAQGVFQILIRNRSTD 1898
>AC004663-1|AAC15789.1| 2281|Homo sapiens Notch 3 protein.
Length = 2281
Score = 70.9 bits (166), Expect = 1e-11
Identities = 53/178 (29%), Positives = 86/178 (48%), Gaps = 3/178 (1%)
Query: 122 AKILIALVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLY 180
A I+ L+ GA L RT R G TA+H A +A K LL+ GA N +D G TPL+
Sbjct: 1778 ASIISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLH 1837
Query: 181 LSVTNKTDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN 239
+VT + + L+ + +T + A G + A R + V+ L+ AD+NA +
Sbjct: 1838 TAVTADAQGVF-QILIRNRSTDLDARMADGSTALILAARLAVEGMVEELIASHADVNAVD 1896
Query: 240 ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
G + LH A LL G +K+ + +TP +A G+ + A+++ ++
Sbjct: 1897 ELGKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDH 1954
Score = 53.2 bits (122), Expect = 2e-06
Identities = 48/194 (24%), Positives = 85/194 (43%), Gaps = 3/194 (1%)
Query: 90 ITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRA 149
I+ +G TGET L +AA + A L++ GA + + G T +H A
Sbjct: 1781 ISDLICQGAQLGARTDRTGETALHLAARY-ARADAAKRLLDAGADTNAQDHSGRTPLHTA 1839
Query: 150 VEKNSLEAVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
V ++ + L+ ++ + + G T L L+ + ++ E L+ HA + A D
Sbjct: 1840 VTADAQGVFQILIRNRSTDLDARMADGSTALILAARLAVEGMV-EELIASHADVNAVDEL 1898
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
G +H A V+ LL GA+ + +++ TPL + A A+ LL ++
Sbjct: 1899 GKSALHWAAAVNNVEATLALLKNGANKDMQDSKEETPLFLAAREGSYEAAKLLLDHFANR 1958
Query: 269 EALNFANQTPYQVA 282
E + ++ P VA
Sbjct: 1959 EITDHLDRLPRDVA 1972
Score = 41.5 bits (93), Expect = 0.007
Identities = 25/78 (32%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 225 VDHLLFYGADMNAR-NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
+ L+ GA + AR + +G T LH+ A A+ A++LL G D A + + +TP AV
Sbjct: 1781 ISDLICQGAQLGARTDRTGETALHLAARYARADAAKRLLDAGADTNAQDHSGRTPLHTAV 1840
Query: 284 IAGNLDLAEV-IKNYKSD 300
A + ++ I+N +D
Sbjct: 1841 TADAQGVFQILIRNRSTD 1858
>X83703-1|CAA58676.1| 319|Homo sapiens nuclear protein protein.
Length = 319
Score = 70.1 bits (164), Expect = 2e-11
Identities = 70/279 (25%), Positives = 119/279 (42%), Gaps = 19/279 (6%)
Query: 22 NGKAGKFLDEERRLGDYP--------------FNGPVGYLELKYKRRVYKMLKLDEKTLK 67
NG+AG+FL E+ R G+Y PV E ++K + +L +K L+
Sbjct: 17 NGEAGEFLPEDFRDGEYEAAVTLEKQEDLKTLLAHPVTLGEQQWKSEKQREAELPKKKLE 76
Query: 68 A---LHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKI 124
L + +L ++ + K K +P E + P + A L++ +
Sbjct: 77 QRSKLENLEDLEIIIQLKKRKKYRKTKVPVVKEPEPEI-ITEPVDVPTFLKAALENKLPV 135
Query: 125 LIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVT 184
+ ++ D TA+HRA + L V+ L+E GA ++D T ++ +
Sbjct: 136 VEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASR 195
Query: 185 NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
+L + LL+ A I A D +H A R G + +HL+ AD+NA++ G+T
Sbjct: 196 GGNLDVL-KLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDT 254
Query: 245 PLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
PLH + R L+ G D N A +TP + +
Sbjct: 255 PLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVL 293
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
Query: 148 RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDL 207
+A +N L V+ L +P+ D T L+ + + + E L+ A I D+
Sbjct: 126 KAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACL-EGHLAIVEKLMEAGAQIEFRDM 184
Query: 208 QGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD 267
+H A R G + + LL GA ++AR+ +T LHV CA L+ D
Sbjct: 185 LESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEAD 244
Query: 268 KEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + TP AV + ++ Y +D
Sbjct: 245 LNAKDREGDTPLHDAVRLNRYKMIRLLIMYGAD 277
>BC110582-1|AAI10583.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/164 (30%), Positives = 80/164 (48%), Gaps = 5/164 (3%)
Query: 124 ILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV 183
++ L G A L+ R + T +H AV K L+ VKTLL+ G P+ +D +G TPL+ ++
Sbjct: 512 VIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAI 571
Query: 184 TNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGAD---MNARNA 240
+ K D +L LL A + T+ G+ +H A G + LL ++ +
Sbjct: 572 SKKRDDILA-VLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKD 630
Query: 241 SGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQVAV 283
G T LH+ A+N A L+ +G + + N QT +AV
Sbjct: 631 DGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAV 674
Score = 53.2 bits (122), Expect = 2e-06
Identities = 47/156 (30%), Positives = 75/156 (48%), Gaps = 15/156 (9%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVN-GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
++ G T L +AA L + ++ LV+ G A LD + + TA+H AVE+ + V+ L+
Sbjct: 629 KDDGYTALHLAA-LNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVR 687
Query: 164 LGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-V 222
GA + +D G TPL+ ++ + T L + L D +G D W+ GL
Sbjct: 688 AGAKLDIQDKDGDTPLHEALRHHTLSQLRQ--LQDMQDVGKVD-AAWEPSKNTLIMGLGT 744
Query: 223 QHVD---------HLLFYGADMNARNASGNTPLHVC 249
Q + L GAD++ RN G +PL +C
Sbjct: 745 QGAEKKSAASIACFLAANGADLSIRNKKGQSPLDLC 780
Score = 52.4 bits (120), Expect = 4e-06
Identities = 51/184 (27%), Positives = 79/184 (42%), Gaps = 7/184 (3%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V G + + G P+ E G+TPL A K IL L+ GA + +
Sbjct: 538 VNKGHLQVVKTLLDFGCHPSLQDSE-GDTPLHDAISKKRD-DILAVLLEAGADVTITNNN 595
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK---GLTPLYLSVTNKTDPLLCETLLHD 198
G A+H A + + A++ LL P D K G T L+L+ N + E L+H
Sbjct: 596 GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEV-AELLVHQ 654
Query: 199 -HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+A + ++ +H A Q V L+ GA ++ ++ G+TPLH + S
Sbjct: 655 GNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQ 714
Query: 258 ARQL 261
RQL
Sbjct: 715 LRQL 718
Score = 48.8 bits (111), Expect = 5e-05
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 5/207 (2%)
Query: 57 KMLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAK-GLDPNFHCQETGETPLTIA 115
++ +L +K + S ++ +G + K+ + +D N C G T + A
Sbjct: 414 RLSQLLKKLFETQESGDLNEELVKAAANGDVAKVEDLLKRPDVDVNGQC--AGHTAMQ-A 470
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKG 175
A IL L+ ++ +DG A+H A + ++ L A N ++ +
Sbjct: 471 ASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRR 530
Query: 176 LTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADM 235
TPL+++V NK + +TLL D +G +H A + LL GAD+
Sbjct: 531 QTPLHIAV-NKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADV 589
Query: 236 NARNASGNTPLHVCAVNAQDSCARQLL 262
N +G LH A+ S R LL
Sbjct: 590 TITNNNGFNALHHAALRGNPSAMRVLL 616
Score = 48.8 bits (111), Expect = 5e-05
Identities = 46/211 (21%), Positives = 84/211 (39%), Gaps = 6/211 (2%)
Query: 77 RFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLD 136
R + H G + + +G + +TPL IA K +++ L++ G
Sbjct: 499 RAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVN-KGHLQVVKTLLDFGCHPS 557
Query: 137 YRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLL 196
+ +G T +H A+ K + + LLE GA + G L+ + + +P LL
Sbjct: 558 LQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAAL-RGNPSAMRVLL 616
Query: 197 HDHATIGATDLQ---GWQEVHQACRNGLVQHVDHLLFYG-ADMNARNASGNTPLHVCAVN 252
D + G+ +H A N V+ + L+ G A+++ +N + T LH+
Sbjct: 617 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER 676
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
R L+ G + + TP A+
Sbjct: 677 QHTQIVRLLVRAGAKLDIQDKDGDTPLHEAL 707
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/153 (24%), Positives = 62/153 (40%), Gaps = 1/153 (0%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G TAM A + ++ +K LL+ +D G ++ + ++ E L A
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVI-EVLHRGSAD 522
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ A + + +H A G +Q V LL +G + +++ G+TPLH +D L
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
L G D N A + GN V+
Sbjct: 583 LEAGADVTITNNNGFNALHHAALRGNPSAMRVL 615
Score = 42.3 bits (95), Expect = 0.004
Identities = 29/110 (26%), Positives = 44/110 (40%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ + LL + + A D G + VH A ++ L AD+NARN TPLH+
Sbjct: 479 ILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAV 538
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ LL GC + TP A+ D+ V+ +D
Sbjct: 539 NKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD 588
Score = 37.9 bits (84), Expect = 0.087
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRG-CD 267
G + A +NG V + LL D+ A + G+ +H A + ++L RG D
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFG-DEGAVIEVLHRGSAD 522
Query: 268 KEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
A N QTP +AV G+L + + + ++
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDF 552
>BC110581-1|AAI10582.1| 1006|Homo sapiens mindbomb homolog 1
(Drosophila) protein.
Length = 1006
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/164 (30%), Positives = 80/164 (48%), Gaps = 5/164 (3%)
Query: 124 ILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV 183
++ L G A L+ R + T +H AV K L+ VKTLL+ G P+ +D +G TPL+ ++
Sbjct: 512 VIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAI 571
Query: 184 TNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGAD---MNARNA 240
+ K D +L LL A + T+ G+ +H A G + LL ++ +
Sbjct: 572 SKKRDDILA-VLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKD 630
Query: 241 SGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQVAV 283
G T LH+ A+N A L+ +G + + N QT +AV
Sbjct: 631 DGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAV 674
Score = 53.2 bits (122), Expect = 2e-06
Identities = 47/156 (30%), Positives = 75/156 (48%), Gaps = 15/156 (9%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVN-GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
++ G T L +AA L + ++ LV+ G A LD + + TA+H AVE+ + V+ L+
Sbjct: 629 KDDGYTALHLAA-LNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVR 687
Query: 164 LGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-V 222
GA + +D G TPL+ ++ + T L + L D +G D W+ GL
Sbjct: 688 AGAKLDIQDKDGDTPLHEALRHHTLSQLRQ--LQDMQDVGKVD-AAWEPSKNTLIMGLGT 744
Query: 223 QHVD---------HLLFYGADMNARNASGNTPLHVC 249
Q + L GAD++ RN G +PL +C
Sbjct: 745 QGAEKKSAASIACFLAANGADLSIRNKKGQSPLDLC 780
Score = 52.4 bits (120), Expect = 4e-06
Identities = 51/184 (27%), Positives = 79/184 (42%), Gaps = 7/184 (3%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V G + + G P+ E G+TPL A K IL L+ GA + +
Sbjct: 538 VNKGHLQVVKTLLDFGCHPSLQDSE-GDTPLHDAISKKRD-DILAVLLEAGADVTITNNN 595
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK---GLTPLYLSVTNKTDPLLCETLLHD 198
G A+H A + + A++ LL P D K G T L+L+ N + E L+H
Sbjct: 596 GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEV-AELLVHQ 654
Query: 199 -HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+A + ++ +H A Q V L+ GA ++ ++ G+TPLH + S
Sbjct: 655 GNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQ 714
Query: 258 ARQL 261
RQL
Sbjct: 715 LRQL 718
Score = 48.8 bits (111), Expect = 5e-05
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 5/207 (2%)
Query: 57 KMLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAK-GLDPNFHCQETGETPLTIA 115
++ +L +K + S ++ +G + K+ + +D N C G T + A
Sbjct: 414 RLSQLLKKLFETQESGDLNEELVKAAANGDVAKVEDLLKRPDVDVNGQC--AGHTAMQ-A 470
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKG 175
A IL L+ ++ +DG A+H A + ++ L A N ++ +
Sbjct: 471 ASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRR 530
Query: 176 LTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADM 235
TPL+++V NK + +TLL D +G +H A + LL GAD+
Sbjct: 531 QTPLHIAV-NKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADV 589
Query: 236 NARNASGNTPLHVCAVNAQDSCARQLL 262
N +G LH A+ S R LL
Sbjct: 590 TITNNNGFNALHHAALRGNPSAMRVLL 616
Score = 48.8 bits (111), Expect = 5e-05
Identities = 46/211 (21%), Positives = 84/211 (39%), Gaps = 6/211 (2%)
Query: 77 RFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLD 136
R + H G + + +G + +TPL IA K +++ L++ G
Sbjct: 499 RAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVN-KGHLQVVKTLLDFGCHPS 557
Query: 137 YRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLL 196
+ +G T +H A+ K + + LLE GA + G L+ + + +P LL
Sbjct: 558 LQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAAL-RGNPSAMRVLL 616
Query: 197 HDHATIGATDLQ---GWQEVHQACRNGLVQHVDHLLFYG-ADMNARNASGNTPLHVCAVN 252
D + G+ +H A N V+ + L+ G A+++ +N + T LH+
Sbjct: 617 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER 676
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
R L+ G + + TP A+
Sbjct: 677 QHTQIVRLLVRAGAKLDIQDKDGDTPLHEAL 707
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/153 (24%), Positives = 62/153 (40%), Gaps = 1/153 (0%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G TAM A + ++ +K LL+ +D G ++ + ++ E L A
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVI-EVLHRGSAD 522
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ A + + +H A G +Q V LL +G + +++ G+TPLH +D L
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
L G D N A + GN V+
Sbjct: 583 LEAGADVTITNNNGFNALHHAALRGNPSAMRVL 615
Score = 42.3 bits (95), Expect = 0.004
Identities = 29/110 (26%), Positives = 44/110 (40%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ + LL + + A D G + VH A ++ L AD+NARN TPLH+
Sbjct: 479 ILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAV 538
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ LL GC + TP A+ D+ V+ +D
Sbjct: 539 NKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD 588
Score = 37.9 bits (84), Expect = 0.087
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRG-CD 267
G + A +NG V + LL D+ A + G+ +H A + ++L RG D
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFG-DEGAVIEVLHRGSAD 522
Query: 268 KEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
A N QTP +AV G+L + + + ++
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDF 552
>BC018667-1|AAH18667.1| 319|Homo sapiens ankyrin repeat domain 1
(cardiac muscle) protein.
Length = 319
Score = 70.1 bits (164), Expect = 2e-11
Identities = 70/279 (25%), Positives = 119/279 (42%), Gaps = 19/279 (6%)
Query: 22 NGKAGKFLDEERRLGDYP--------------FNGPVGYLELKYKRRVYKMLKLDEKTLK 67
NG+AG+FL E+ R G+Y PV E ++K + +L +K L+
Sbjct: 17 NGEAGEFLPEDFRDGEYEAAVTLEKQEDLKTLLAHPVTLGEQQWKSEKQREAELKKKKLE 76
Query: 68 A---LHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKI 124
L + +L ++ + K K +P E + P + A L++ +
Sbjct: 77 QRSKLENLEDLEIIIQLKKRKKYRKTKVPVVKEPEPEI-ITEPVDVPTFLKAALENKLPV 135
Query: 125 LIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVT 184
+ ++ D TA+HRA + L V+ L+E GA ++D T ++ +
Sbjct: 136 VEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASR 195
Query: 185 NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
+L + LL+ A I A D +H A R G + +HL+ AD+NA++ G+T
Sbjct: 196 GGNLDVL-KLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDT 254
Query: 245 PLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
PLH + R L+ G D N A +TP + +
Sbjct: 255 PLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVL 293
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
Query: 148 RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDL 207
+A +N L V+ L +P+ D T L+ + + + E L+ A I D+
Sbjct: 126 KAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACL-EGHLAIVEKLMEAGAQIEFRDM 184
Query: 208 QGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD 267
+H A R G + + LL GA ++AR+ +T LHV CA L+ D
Sbjct: 185 LESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEAD 244
Query: 268 KEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + TP AV + ++ Y +D
Sbjct: 245 LNAKDREGDTPLHDAVRLNRYKMIRLLIMYGAD 277
>AY903446-1|AAX23581.1| 319|Homo sapiens liver ankyrin repeat
domain 1 protein.
Length = 319
Score = 70.1 bits (164), Expect = 2e-11
Identities = 70/279 (25%), Positives = 119/279 (42%), Gaps = 19/279 (6%)
Query: 22 NGKAGKFLDEERRLGDYP--------------FNGPVGYLELKYKRRVYKMLKLDEKTLK 67
NG+AG+FL E+ R G+Y PV E ++K + +L +K L+
Sbjct: 17 NGEAGEFLPEDFRDGEYEAAVTLEKQEDLKTLLAHPVTLGEQQWKSEKQREAELKKKKLE 76
Query: 68 A---LHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKI 124
L + +L ++ + K K +P E + P + A L++ +
Sbjct: 77 QRSKLENLEDLEIIIQLKKRKKYRKTKVPVVKEPEPEI-ITEPVDVPTFLKAALENKLPV 135
Query: 125 LIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVT 184
+ ++ D TA+HRA + L V+ L+E GA ++D T ++ +
Sbjct: 136 VEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASR 195
Query: 185 NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
+L + LL+ A I A D +H A R G + +HL+ AD+NA++ G+T
Sbjct: 196 GGNLDVL-KLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDT 254
Query: 245 PLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
PLH + R L+ G D N A +TP + +
Sbjct: 255 PLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVL 293
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
Query: 148 RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDL 207
+A +N L V+ L +P+ D T L+ + + + E L+ A I D+
Sbjct: 126 KAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACL-EGHLAIVEKLMEAGAQIEFRDM 184
Query: 208 QGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD 267
+H A R G + + LL GA ++AR+ +T LHV CA L+ D
Sbjct: 185 LESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEAD 244
Query: 268 KEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + TP AV + ++ Y +D
Sbjct: 245 LNAKDREGDTPLHDAVRLNRYKMIRLLIMYGAD 277
>AY149908-1|AAN75493.1| 1006|Homo sapiens mind bomb protein.
Length = 1006
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/164 (30%), Positives = 80/164 (48%), Gaps = 5/164 (3%)
Query: 124 ILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV 183
++ L G A L+ R + T +H AV K L+ VKTLL+ G P+ +D +G TPL+ ++
Sbjct: 512 VIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAI 571
Query: 184 TNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGAD---MNARNA 240
+ K D +L LL A + T+ G+ +H A G + LL ++ +
Sbjct: 572 SKKRDDILA-VLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKD 630
Query: 241 SGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQVAV 283
G T LH+ A+N A L+ +G + + N QT +AV
Sbjct: 631 DGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAV 674
Score = 53.2 bits (122), Expect = 2e-06
Identities = 47/156 (30%), Positives = 75/156 (48%), Gaps = 15/156 (9%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVN-GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
++ G T L +AA L + ++ LV+ G A LD + + TA+H AVE+ + V+ L+
Sbjct: 629 KDDGYTALHLAA-LNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVR 687
Query: 164 LGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-V 222
GA + +D G TPL+ ++ + T L + L D +G D W+ GL
Sbjct: 688 AGAKLDIQDKDGDTPLHEALRHHTLSQLRQ--LQDMQDVGKVD-AAWEPSKNTLIMGLGT 744
Query: 223 QHVD---------HLLFYGADMNARNASGNTPLHVC 249
Q + L GAD++ RN G +PL +C
Sbjct: 745 QGAEKKSAASIACFLAANGADLSIRNKKGQSPLDLC 780
Score = 52.4 bits (120), Expect = 4e-06
Identities = 51/184 (27%), Positives = 79/184 (42%), Gaps = 7/184 (3%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V G + + G P+ E G+TPL A K IL L+ GA + +
Sbjct: 538 VNKGHLQVVKTLLDFGCHPSLQDSE-GDTPLHDAISKKRD-DILAVLLEAGADVTITNNN 595
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK---GLTPLYLSVTNKTDPLLCETLLHD 198
G A+H A + + A++ LL P D K G T L+L+ N + E L+H
Sbjct: 596 GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEV-AELLVHQ 654
Query: 199 -HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+A + ++ +H A Q V L+ GA ++ ++ G+TPLH + S
Sbjct: 655 GNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQ 714
Query: 258 ARQL 261
RQL
Sbjct: 715 LRQL 718
Score = 48.8 bits (111), Expect = 5e-05
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 5/207 (2%)
Query: 57 KMLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAK-GLDPNFHCQETGETPLTIA 115
++ +L +K + S ++ +G + K+ + +D N C G T + A
Sbjct: 414 RLSQLLKKLFETQESGDLNEELVKAAANGDVAKVEDLLKRPDVDVNGQC--AGHTAMQ-A 470
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKG 175
A IL L+ ++ +DG A+H A + ++ L A N ++ +
Sbjct: 471 ASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRR 530
Query: 176 LTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADM 235
TPL+++V NK + +TLL D +G +H A + LL GAD+
Sbjct: 531 QTPLHIAV-NKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADV 589
Query: 236 NARNASGNTPLHVCAVNAQDSCARQLL 262
N +G LH A+ S R LL
Sbjct: 590 TITNNNGFNALHHAALRGNPSAMRVLL 616
Score = 48.8 bits (111), Expect = 5e-05
Identities = 46/211 (21%), Positives = 84/211 (39%), Gaps = 6/211 (2%)
Query: 77 RFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLD 136
R + H G + + +G + +TPL IA K +++ L++ G
Sbjct: 499 RAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVN-KGHLQVVKTLLDFGCHPS 557
Query: 137 YRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLL 196
+ +G T +H A+ K + + LLE GA + G L+ + + +P LL
Sbjct: 558 LQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAAL-RGNPSAMRVLL 616
Query: 197 HDHATIGATDLQ---GWQEVHQACRNGLVQHVDHLLFYG-ADMNARNASGNTPLHVCAVN 252
D + G+ +H A N V+ + L+ G A+++ +N + T LH+
Sbjct: 617 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER 676
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
R L+ G + + TP A+
Sbjct: 677 QHTQIVRLLVRAGAKLDIQDKDGDTPLHEAL 707
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/153 (24%), Positives = 62/153 (40%), Gaps = 1/153 (0%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G TAM A + ++ +K LL+ +D G ++ + ++ E L A
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVI-EVLHRGSAD 522
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ A + + +H A G +Q V LL +G + +++ G+TPLH +D L
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 582
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
L G D N A + GN V+
Sbjct: 583 LEAGADVTITNNNGFNALHHAALRGNPSAMRVL 615
Score = 42.3 bits (95), Expect = 0.004
Identities = 29/110 (26%), Positives = 44/110 (40%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ + LL + + A D G + VH A ++ L AD+NARN TPLH+
Sbjct: 479 ILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAV 538
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ LL GC + TP A+ D+ V+ +D
Sbjct: 539 NKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD 588
Score = 37.9 bits (84), Expect = 0.087
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRG-CD 267
G + A +NG V + LL D+ A + G+ +H A + ++L RG D
Sbjct: 464 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFG-DEGAVIEVLHRGSAD 522
Query: 268 KEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
A N QTP +AV G+L + + + ++
Sbjct: 523 LNARNKRRQTPLHIAVNKGHLQVVKTLLDF 552
>AY147849-1|AAN18023.1| 997|Homo sapiens MINDBOMB protein.
Length = 997
Score = 70.1 bits (164), Expect = 2e-11
Identities = 50/164 (30%), Positives = 80/164 (48%), Gaps = 5/164 (3%)
Query: 124 ILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSV 183
++ L G A L+ R + T +H AV K L+ VKTLL+ G P+ +D +G TPL+ ++
Sbjct: 503 VIEVLHRGSADLNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAI 562
Query: 184 TNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGAD---MNARNA 240
+ K D +L LL A + T+ G+ +H A G + LL ++ +
Sbjct: 563 SKKRDDILA-VLLEAGADVTITNNNGFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKD 621
Query: 241 SGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQVAV 283
G T LH+ A+N A L+ +G + + N QT +AV
Sbjct: 622 DGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAV 665
Score = 53.2 bits (122), Expect = 2e-06
Identities = 47/156 (30%), Positives = 75/156 (48%), Gaps = 15/156 (9%)
Query: 105 QETGETPLTIAAGLKSPAKILIALVN-GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE 163
++ G T L +AA L + ++ LV+ G A LD + + TA+H AVE+ + V+ L+
Sbjct: 620 KDDGYTALHLAA-LNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVERQHTQIVRLLVR 678
Query: 164 LGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-V 222
GA + +D G TPL+ ++ + T L + L D +G D W+ GL
Sbjct: 679 AGAKLDIQDKDGDTPLHEALRHHTLSQLRQ--LQDMQDVGKVD-AAWEPSKNTLIMGLGT 735
Query: 223 QHVD---------HLLFYGADMNARNASGNTPLHVC 249
Q + L GAD++ RN G +PL +C
Sbjct: 736 QGAEKKSAASIACFLAANGADLSIRNKKGQSPLDLC 771
Score = 52.4 bits (120), Expect = 4e-06
Identities = 51/184 (27%), Positives = 79/184 (42%), Gaps = 7/184 (3%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V G + + G P+ E G+TPL A K IL L+ GA + +
Sbjct: 529 VNKGHLQVVKTLLDFGCHPSLQDSE-GDTPLHDAISKKRD-DILAVLLEAGADVTITNNN 586
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK---GLTPLYLSVTNKTDPLLCETLLHD 198
G A+H A + + A++ LL P D K G T L+L+ N + E L+H
Sbjct: 587 GFNALHHAALRGNPSAMRVLLSKLPRPWIVDEKKDDGYTALHLAALNNHVEV-AELLVHQ 645
Query: 199 -HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
+A + ++ +H A Q V L+ GA ++ ++ G+TPLH + S
Sbjct: 646 GNANLDIQNVNQQTALHLAVERQHTQIVRLLVRAGAKLDIQDKDGDTPLHEALRHHTLSQ 705
Query: 258 ARQL 261
RQL
Sbjct: 706 LRQL 709
Score = 48.8 bits (111), Expect = 5e-05
Identities = 50/207 (24%), Positives = 85/207 (41%), Gaps = 5/207 (2%)
Query: 57 KMLKLDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAK-GLDPNFHCQETGETPLTIA 115
++ +L +K + S ++ +G + K+ + +D N C G T + A
Sbjct: 405 RLSQLLKKLFETQESGDLNEELVKAAANGDVAKVEDLLKRPDVDVNGQC--AGHTAMQ-A 461
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKG 175
A IL L+ ++ +DG A+H A + ++ L A N ++ +
Sbjct: 462 ASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRR 521
Query: 176 LTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADM 235
TPL+++V NK + +TLL D +G +H A + LL GAD+
Sbjct: 522 QTPLHIAV-NKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGADV 580
Query: 236 NARNASGNTPLHVCAVNAQDSCARQLL 262
N +G LH A+ S R LL
Sbjct: 581 TITNNNGFNALHHAALRGNPSAMRVLL 607
Score = 48.8 bits (111), Expect = 5e-05
Identities = 46/211 (21%), Positives = 84/211 (39%), Gaps = 6/211 (2%)
Query: 77 RFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLD 136
R + H G + + +G + +TPL IA K +++ L++ G
Sbjct: 490 RAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAVN-KGHLQVVKTLLDFGCHPS 548
Query: 137 YRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLL 196
+ +G T +H A+ K + + LLE GA + G L+ + + +P LL
Sbjct: 549 LQDSEGDTPLHDAISKKRDDILAVLLEAGADVTITNNNGFNALHHAAL-RGNPSAMRVLL 607
Query: 197 HDHATIGATDLQ---GWQEVHQACRNGLVQHVDHLLFYG-ADMNARNASGNTPLHVCAVN 252
D + G+ +H A N V+ + L+ G A+++ +N + T LH+
Sbjct: 608 SKLPRPWIVDEKKDDGYTALHLAALNNHVEVAELLVHQGNANLDIQNVNQQTALHLAVER 667
Query: 253 AQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
R L+ G + + TP A+
Sbjct: 668 QHTQIVRLLVRAGAKLDIQDKDGDTPLHEAL 698
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/153 (24%), Positives = 62/153 (40%), Gaps = 1/153 (0%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G TAM A + ++ +K LL+ +D G ++ + ++ E L A
Sbjct: 455 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVI-EVLHRGSAD 513
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ A + + +H A G +Q V LL +G + +++ G+TPLH +D L
Sbjct: 514 LNARNKRRQTPLHIAVNKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVL 573
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
L G D N A + GN V+
Sbjct: 574 LEAGADVTITNNNGFNALHHAALRGNPSAMRVL 606
Score = 42.3 bits (95), Expect = 0.004
Identities = 29/110 (26%), Positives = 44/110 (40%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ + LL + + A D G + VH A ++ L AD+NARN TPLH+
Sbjct: 470 ILKLLLKQNVDVEAEDKDGDRAVHHAAFGDEGAVIEVLHRGSADLNARNKRRQTPLHIAV 529
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ LL GC + TP A+ D+ V+ +D
Sbjct: 530 NKGHLQVVKTLLDFGCHPSLQDSEGDTPLHDAISKKRDDILAVLLEAGAD 579
Score = 37.9 bits (84), Expect = 0.087
Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 2/90 (2%)
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRG-CD 267
G + A +NG V + LL D+ A + G+ +H A + ++L RG D
Sbjct: 455 GHTAMQAASQNGHVDILKLLLKQNVDVEAEDKDGDRAVHHAAFG-DEGAVIEVLHRGSAD 513
Query: 268 KEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
A N QTP +AV G+L + + + ++
Sbjct: 514 LNARNKRRQTPLHIAVNKGHLQVVKTLLDF 543
>AL590622-4|CAC70101.1| 319|Homo sapiens ankyrin repeat domain 1
(cardiac muscle) protein.
Length = 319
Score = 70.1 bits (164), Expect = 2e-11
Identities = 70/279 (25%), Positives = 119/279 (42%), Gaps = 19/279 (6%)
Query: 22 NGKAGKFLDEERRLGDYP--------------FNGPVGYLELKYKRRVYKMLKLDEKTLK 67
NG+AG+FL E+ R G+Y PV E ++K + +L +K L+
Sbjct: 17 NGEAGEFLPEDFRDGEYEAAVTLEKQEDLKTLLAHPVTLGEQQWKSEKQREAELKKKKLE 76
Query: 68 A---LHSRANLRRFLEHVTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKI 124
L + +L ++ + K K +P E + P + A L++ +
Sbjct: 77 QRSKLENLEDLEIIIQLKKRKKYRKTKVPVVKEPEPEI-ITEPVDVPTFLKAALENKLPV 135
Query: 125 LIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVT 184
+ ++ D TA+HRA + L V+ L+E GA ++D T ++ +
Sbjct: 136 VEKFLSDKNNPDVCDEYKRTALHRACLEGHLAIVEKLMEAGAQIEFRDMLESTAIHWASR 195
Query: 185 NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNT 244
+L + LL+ A I A D +H A R G + +HL+ AD+NA++ G+T
Sbjct: 196 GGNLDVL-KLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEADLNAKDREGDT 254
Query: 245 PLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
PLH + R L+ G D N A +TP + +
Sbjct: 255 PLHDAVRLNRYKMIRLLIMYGADLNIKNCAGKTPMDLVL 293
Score = 43.2 bits (97), Expect = 0.002
Identities = 39/153 (25%), Positives = 63/153 (41%), Gaps = 1/153 (0%)
Query: 148 RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDL 207
+A +N L V+ L +P+ D T L+ + + + E L+ A I D+
Sbjct: 126 KAALENKLPVVEKFLSDKNNPDVCDEYKRTALHRACL-EGHLAIVEKLMEAGAQIEFRDM 184
Query: 208 QGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD 267
+H A R G + + LL GA ++AR+ +T LHV CA L+ D
Sbjct: 185 LESTAIHWASRGGNLDVLKLLLNKGAKISARDKLLSTALHVAVRTGHYECAEHLIACEAD 244
Query: 268 KEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
A + TP AV + ++ Y +D
Sbjct: 245 LNAKDREGDTPLHDAVRLNRYKMIRLLIMYGAD 277
>AK222595-1|BAD96315.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 518
Score = 69.7 bits (163), Expect = 2e-11
Identities = 59/219 (26%), Positives = 94/219 (42%), Gaps = 5/219 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY---RTRD 141
G + + K KG + G P+ AA S + L L+N + +Y +T +
Sbjct: 21 GNVKVLRKLLKKGRSVDV-ADNRGWMPIHEAAYHNS-VECLQMLINADSSENYIKMKTFE 78
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G A+H A + + V+ LLE GA PN + TPL+L+V N +L L H
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
G+ + GW +HQA + + LL GA+ ++ G TPL V A + L
Sbjct: 139 NGSHSMCGWNSLHQASFQDNAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSIL 198
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ G + TP +A G+ E++ + +D
Sbjct: 199 ISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGAD 237
Score = 56.8 bits (131), Expect = 2e-07
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 5/183 (2%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY---KD 172
A + K+L L+ G +D G +H A NS+E ++ L+ +S NY K
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
+G L+L+ + ++ + LL A AT L+ + A NG + + LL +G
Sbjct: 77 FEGFCALHLAASQGHWKIV-QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 233 ADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
A++N + + G LH + + LL +G +KE + TP VA G L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQDNAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 292 EVI 294
++
Sbjct: 196 SIL 198
Score = 48.4 bits (110), Expect = 6e-05
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK-GLTPLYL 181
KI+ L+ GA + T + +T + AVE ++ ++ LL+ GA+ N G L+
Sbjct: 93 KIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLH- 151
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNAS 241
+ + + + + LL A D G + A + G ++ + L+ GA++N +
Sbjct: 152 QASFQDNAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALD 211
Query: 242 GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
TPL + A C LL G D + + N+ +Q+ + A
Sbjct: 212 KATPLFIAAQEGHTKCVELLLSSGADPDL--YCNEDSWQLPIHA 253
>BC110915-1|AAI10916.1| 553|Homo sapiens ASB3 protein protein.
Length = 553
Score = 69.3 bits (162), Expect = 3e-11
Identities = 59/219 (26%), Positives = 94/219 (42%), Gaps = 5/219 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY---RTRD 141
G + + K KG + G P+ AA S + L L+N + +Y +T +
Sbjct: 56 GNVKVLRKLLKKGRSVDV-ADNRGWMPIHEAAYHNS-VECLQMLINADSSENYIKMKTFE 113
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G A+H A + + V+ LLE GA PN + TPL+L+V N +L L H
Sbjct: 114 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 173
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
G+ + GW +HQA + + LL GA+ ++ G TPL V A + L
Sbjct: 174 NGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSIL 233
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ G + TP +A G+ E++ + +D
Sbjct: 234 ISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGAD 272
Score = 57.2 bits (132), Expect = 1e-07
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 5/183 (2%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY---KD 172
A + K+L L+ G +D G +H A NS+E ++ L+ +S NY K
Sbjct: 52 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 111
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
+G L+L+ + ++ + LL A AT L+ + A NG + + LL +G
Sbjct: 112 FEGFCALHLAASQGHWKIV-QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 170
Query: 233 ADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
A++N + + G LH + + LL +G +KE + TP VA G L+
Sbjct: 171 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 230
Query: 292 EVI 294
++
Sbjct: 231 SIL 233
Score = 48.8 bits (111), Expect = 5e-05
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK-GLTPLYL 181
KI+ L+ GA + T + +T + AVE ++ ++ LL+ GA+ N G L+
Sbjct: 128 KIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQ 187
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNAS 241
+ + ++ + LL A D G + A + G ++ + L+ GA++N +
Sbjct: 188 ASFQENAEII-KLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALD 246
Query: 242 GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
TPL + A C LL G D + + N+ +Q+ + A
Sbjct: 247 KATPLFIAAQEGHTKCVELLLSSGADPDL--YCNEDSWQLPIHA 288
>BC050529-1|AAH50529.1| 1050|Homo sapiens ankyrin repeat domain 27
(VPS9 domain) protein.
Length = 1050
Score = 69.3 bits (162), Expect = 3e-11
Identities = 51/166 (30%), Positives = 80/166 (48%), Gaps = 3/166 (1%)
Query: 89 KITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHR 148
++ K A GL N Q+ G +PL +AA L A ++ L+ GA R D + +H
Sbjct: 726 RLAKVPASGLGVNVTSQD-GSSPLHVAA-LHGRADLIPLLLKHGANAGARNADQAVPLHL 783
Query: 149 AVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
A ++ + VK LL+ A PN KD G TPL + + L+ L H A+I A++ +
Sbjct: 784 ACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHG-ASINASNNK 842
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
G +H+A V V+ LL +GA + N T + N++
Sbjct: 843 GNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSK 888
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/140 (28%), Positives = 68/140 (48%), Gaps = 5/140 (3%)
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVD 226
+P +D +G TPL+++ L+ + L+ A + ATD G +H AC+ G
Sbjct: 455 TPFSRDDRGHTPLHVAAVCGQASLI-DLLVSKGAMVNATDYHGATPLHLACQKGYQSVTL 513
Query: 227 HLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQ---TPYQVAV 283
LL Y A ++ +GNTPLH+ + C + L++ + L+ N+ TP +A
Sbjct: 514 LLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAA 573
Query: 284 IAGNLDLAE-VIKNYKSDEI 302
G + E +++N S EI
Sbjct: 574 RWGYQGVIETLLQNGASTEI 593
Score = 62.5 bits (145), Expect = 4e-09
Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
Query: 120 SPAKILIALVNGGAL-LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTP 178
+PA+ +A V L ++ ++DGS+ +H A + + LL+ GA+ ++ P
Sbjct: 721 APAQKRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVP 780
Query: 179 LYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
L+L+ ++ + LL +A DL G + AC G + V LL +GA +NA
Sbjct: 781 LHLACQQGHFQVV-KCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINAS 839
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
N GNT LH + LL G + LN +T A
Sbjct: 840 NNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCA 883
Score = 61.3 bits (142), Expect = 8e-09
Identities = 55/198 (27%), Positives = 84/198 (42%), Gaps = 12/198 (6%)
Query: 123 KILIALVNGGALLDYRTRD--GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLY 180
K++ +N +++ +RD G T +H A + L+ GA N D G TPL+
Sbjct: 442 KLVSGRLNDPSVVTPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLH 501
Query: 181 LSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGAD---MNA 237
L+ K + LLH A+ D G +H AC G V L++Y + ++
Sbjct: 502 LAC-QKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDI 560
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI--- 294
N G+TPLH+ A LL G E N +TP + A+ + L + E
Sbjct: 561 GNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKILSVMEAYHLS 620
Query: 295 --KNYKSDEIVPFRGPPR 310
+ KS E P + P R
Sbjct: 621 FERRQKSSE-APVQSPQR 637
Score = 60.1 bits (139), Expect = 2e-08
Identities = 45/155 (29%), Positives = 74/155 (47%), Gaps = 4/155 (2%)
Query: 102 FHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTL 161
F + G TPL +AA + A ++ LV+ GA+++ G+T +H A +K L
Sbjct: 457 FSRDDRGHTPLHVAA-VCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLL 515
Query: 162 LELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHD--HATIGATDLQGWQEVHQACRN 219
L AS +D G TPL+L+ T + + + +D + + +G +H A R
Sbjct: 516 LHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARW 575
Query: 220 GLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
G ++ LL GA +N TPL CA+N++
Sbjct: 576 GYQGVIETLLQNGASTEIQNRLKETPLK-CALNSK 609
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/130 (28%), Positives = 53/130 (40%), Gaps = 1/130 (0%)
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
G N G +PL+++ + L+ L H A GA + +H AC+ G Q
Sbjct: 734 GLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHG-ANAGARNADQAVPLHLACQQGHFQV 792
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
V LL A N ++ SGNTPL LL G A N T AVI
Sbjct: 793 VKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVI 852
Query: 285 AGNLDLAEVI 294
++ + E++
Sbjct: 853 EKHVFVVELL 862
>BC009569-1|AAH09569.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 69.3 bits (162), Expect = 3e-11
Identities = 59/219 (26%), Positives = 94/219 (42%), Gaps = 5/219 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY---RTRD 141
G + + K KG + G P+ AA S + L L+N + +Y +T +
Sbjct: 21 GNVKVLRKLLKKGRSVDV-ADNRGWMPIHEAAYHNS-VECLQMLINADSSENYIKMKTFE 78
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G A+H A + + V+ LLE GA PN + TPL+L+V N +L L H
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
G+ + GW +HQA + + LL GA+ ++ G TPL V A + L
Sbjct: 139 NGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSIL 198
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ G + TP +A G+ E++ + +D
Sbjct: 199 ISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGAD 237
Score = 57.2 bits (132), Expect = 1e-07
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 5/183 (2%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY---KD 172
A + K+L L+ G +D G +H A NS+E ++ L+ +S NY K
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
+G L+L+ + ++ + LL A AT L+ + A NG + + LL +G
Sbjct: 77 FEGFCALHLAASQGHWKIV-QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 233 ADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
A++N + + G LH + + LL +G +KE + TP VA G L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 292 EVI 294
++
Sbjct: 196 SIL 198
Score = 48.8 bits (111), Expect = 5e-05
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK-GLTPLYL 181
KI+ L+ GA + T + +T + AVE ++ ++ LL+ GA+ N G L+
Sbjct: 93 KIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQ 152
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNAS 241
+ + ++ + LL A D G + A + G ++ + L+ GA++N +
Sbjct: 153 ASFQENAEII-KLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALD 211
Query: 242 GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
TPL + A C LL G D + + N+ +Q+ + A
Sbjct: 212 KATPLFIAAQEGHTKCVELLLSSGADPDL--YCNEDSWQLPIHA 253
>BC006488-1|AAH06488.1| 518|Homo sapiens ankyrin repeat and SOCS
box-containing 3 protein.
Length = 518
Score = 69.3 bits (162), Expect = 3e-11
Identities = 59/219 (26%), Positives = 94/219 (42%), Gaps = 5/219 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY---RTRD 141
G + + K KG + G P+ AA S + L L+N + +Y +T +
Sbjct: 21 GNVKVLRKLLKKGRSVDV-ADNRGWMPIHEAAYHNS-VECLQMLINADSSENYIKMKTFE 78
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G A+H A + + V+ LLE GA PN + TPL+L+V N +L L H
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
G+ + GW +HQA + + LL GA+ ++ G TPL V A + L
Sbjct: 139 NGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSIL 198
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ G + TP +A G+ E++ + +D
Sbjct: 199 ISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGAD 237
Score = 57.2 bits (132), Expect = 1e-07
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 5/183 (2%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY---KD 172
A + K+L L+ G +D G +H A NS+E ++ L+ +S NY K
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
+G L+L+ + ++ + LL A AT L+ + A NG + + LL +G
Sbjct: 77 FEGFCALHLAASQGHWKIV-QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 233 ADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
A++N + + G LH + + LL +G +KE + TP VA G L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 292 EVI 294
++
Sbjct: 196 SIL 198
Score = 48.8 bits (111), Expect = 5e-05
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK-GLTPLYL 181
KI+ L+ GA + T + +T + AVE ++ ++ LL+ GA+ N G L+
Sbjct: 93 KIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQ 152
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNAS 241
+ + ++ + LL A D G + A + G ++ + L+ GA++N +
Sbjct: 153 ASFQENAEII-KLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALD 211
Query: 242 GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
TPL + A C LL G D + + N+ +Q+ + A
Sbjct: 212 KATPLFIAAQEGHTKCVELLLSSGADPDL--YCNEDSWQLPIHA 253
>AL834335-1|CAD39003.1| 407|Homo sapiens hypothetical protein
protein.
Length = 407
Score = 69.3 bits (162), Expect = 3e-11
Identities = 51/166 (30%), Positives = 80/166 (48%), Gaps = 3/166 (1%)
Query: 89 KITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHR 148
++ K A GL N Q+ G +PL +AA L A ++ L+ GA R D + +H
Sbjct: 83 RLAKVPASGLGVNVTSQD-GSSPLHVAA-LHGRADLIPLLLKHGANAGARNADQAVPLHL 140
Query: 149 AVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
A ++ + VK LL+ A PN KD G TPL + + L+ L H A+I A++ +
Sbjct: 141 ACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHG-ASINASNNK 199
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
G +H+A V V+ LL +GA + N T + N++
Sbjct: 200 GNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSK 245
Score = 62.5 bits (145), Expect = 4e-09
Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
Query: 120 SPAKILIALVNGGAL-LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTP 178
+PA+ +A V L ++ ++DGS+ +H A + + LL+ GA+ ++ P
Sbjct: 78 APAQKRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVP 137
Query: 179 LYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
L+L+ ++ + LL +A DL G + AC G + V LL +GA +NA
Sbjct: 138 LHLACQQGHFQVV-KCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINAS 196
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
N GNT LH + LL G + LN +T A
Sbjct: 197 NNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCA 240
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/130 (28%), Positives = 53/130 (40%), Gaps = 1/130 (0%)
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
G N G +PL+++ + L+ L H A GA + +H AC+ G Q
Sbjct: 91 GLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHG-ANAGARNADQAVPLHLACQQGHFQV 149
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
V LL A N ++ SGNTPL LL G A N T AVI
Sbjct: 150 VKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVI 209
Query: 285 AGNLDLAEVI 294
++ + E++
Sbjct: 210 EKHVFVVELL 219
>AK054561-1|BAB70755.1| 1060|Homo sapiens FLJ00040 protein protein.
Length = 1060
Score = 69.3 bits (162), Expect = 3e-11
Identities = 51/166 (30%), Positives = 80/166 (48%), Gaps = 3/166 (1%)
Query: 89 KITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHR 148
++ K A GL N Q+ G +PL +AA L A ++ L+ GA R D + +H
Sbjct: 736 RLAKVPASGLGVNVTSQD-GSSPLHVAA-LHGRADLIPLLLKHGANAGARNADQAVPLHL 793
Query: 149 AVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
A ++ + VK LL+ A PN KD G TPL + + L+ L H A+I A++ +
Sbjct: 794 ACQQGHFQVVKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHG-ASINASNNK 852
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
G +H+A V V+ LL +GA + N T + N++
Sbjct: 853 GNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCAEQNSK 898
Score = 62.5 bits (145), Expect = 4e-09
Identities = 40/140 (28%), Positives = 68/140 (48%), Gaps = 5/140 (3%)
Query: 167 SPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVD 226
+P +D +G TPL+++ L+ + L+ A + ATD G +H AC+ G
Sbjct: 465 TPFSRDDRGHTPLHVAAVCGQASLI-DLLVSKGAMVNATDYHGATPLHLACQKGYQSVTL 523
Query: 227 HLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQ---TPYQVAV 283
LL Y A ++ +GNTPLH+ + C + L++ + L+ N+ TP +A
Sbjct: 524 LLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAA 583
Query: 284 IAGNLDLAE-VIKNYKSDEI 302
G + E +++N S EI
Sbjct: 584 RWGYQGVIETLLQNGASTEI 603
Score = 62.5 bits (145), Expect = 4e-09
Identities = 46/164 (28%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
Query: 120 SPAKILIALVNGGAL-LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTP 178
+PA+ +A V L ++ ++DGS+ +H A + + LL+ GA+ ++ P
Sbjct: 731 APAQKRLAKVPASGLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHGANAGARNADQAVP 790
Query: 179 LYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
L+L+ ++ + LL +A DL G + AC G + V LL +GA +NA
Sbjct: 791 LHLACQQGHFQVV-KCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINAS 849
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
N GNT LH + LL G + LN +T A
Sbjct: 850 NNKGNTALHEAVIEKHVFVVELLLLHGASVQVLNKRQRTAVDCA 893
Score = 61.3 bits (142), Expect = 8e-09
Identities = 55/198 (27%), Positives = 84/198 (42%), Gaps = 12/198 (6%)
Query: 123 KILIALVNGGALLDYRTRD--GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLY 180
K++ +N +++ +RD G T +H A + L+ GA N D G TPL+
Sbjct: 452 KLVSGRLNDPSVVTPFSRDDRGHTPLHVAAVCGQASLIDLLVSKGAMVNATDYHGATPLH 511
Query: 181 LSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGAD---MNA 237
L+ K + LLH A+ D G +H AC G V L++Y + ++
Sbjct: 512 LAC-QKGYQSVTLLLLHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDI 570
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI--- 294
N G+TPLH+ A LL G E N +TP + A+ + L + E
Sbjct: 571 GNEKGDTPLHIAARWGYQGVIETLLQNGASTEIQNRLKETPLKCALNSKILSVMEAYHLS 630
Query: 295 --KNYKSDEIVPFRGPPR 310
+ KS E P + P R
Sbjct: 631 FERRQKSSE-APVQSPQR 647
Score = 60.1 bits (139), Expect = 2e-08
Identities = 45/155 (29%), Positives = 74/155 (47%), Gaps = 4/155 (2%)
Query: 102 FHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTL 161
F + G TPL +AA + A ++ LV+ GA+++ G+T +H A +K L
Sbjct: 467 FSRDDRGHTPLHVAA-VCGQASLIDLLVSKGAMVNATDYHGATPLHLACQKGYQSVTLLL 525
Query: 162 LELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHD--HATIGATDLQGWQEVHQACRN 219
L AS +D G TPL+L+ T + + + +D + + +G +H A R
Sbjct: 526 LHYKASAEVQDNNGNTPLHLACTYGHEDCVKALVYYDVESCRLDIGNEKGDTPLHIAARW 585
Query: 220 GLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
G ++ LL GA +N TPL CA+N++
Sbjct: 586 GYQGVIETLLQNGASTEIQNRLKETPLK-CALNSK 619
Score = 46.8 bits (106), Expect = 2e-04
Identities = 37/130 (28%), Positives = 53/130 (40%), Gaps = 1/130 (0%)
Query: 165 GASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
G N G +PL+++ + L+ L H A GA + +H AC+ G Q
Sbjct: 744 GLGVNVTSQDGSSPLHVAALHGRADLIPLLLKHG-ANAGARNADQAVPLHLACQQGHFQV 802
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVI 284
V LL A N ++ SGNTPL LL G A N T AVI
Sbjct: 803 VKCLLDSNAKPNKKDLSGNTPLIYACSGGHHELVALLLQHGASINASNNKGNTALHEAVI 862
Query: 285 AGNLDLAEVI 294
++ + E++
Sbjct: 863 EKHVFVVELL 872
>AK000985-1|BAA91455.1| 518|Homo sapiens protein ( Homo sapiens
cDNA FLJ10123 fis, clone HEMBA1002939, weakly similar to
ANKYRIN R. ).
Length = 518
Score = 69.3 bits (162), Expect = 3e-11
Identities = 59/219 (26%), Positives = 94/219 (42%), Gaps = 5/219 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY---RTRD 141
G + + K KG + G P+ AA S + L L+N + +Y +T +
Sbjct: 21 GNVKVLRKLLKKGRSVDV-ADNRGWMPIHEAAYHNS-VECLQMLINADSSENYIKMKTFE 78
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G A+H A + + V+ LLE GA PN + TPL+L+V N +L L H
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
G+ + GW +HQA + + LL GA+ ++ G TPL V A + L
Sbjct: 139 NGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSIL 198
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ G + TP +A G+ E++ + +D
Sbjct: 199 ISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGAD 237
Score = 57.2 bits (132), Expect = 1e-07
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 5/183 (2%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY---KD 172
A + K+L L+ G +D G +H A NS+E ++ L+ +S NY K
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
+G L+L+ + ++ + LL A AT L+ + A NG + + LL +G
Sbjct: 77 FEGFCALHLAASQGHWKIV-QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 233 ADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
A++N + + G LH + + LL +G +KE + TP VA G L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 292 EVI 294
++
Sbjct: 196 SIL 198
Score = 48.8 bits (111), Expect = 5e-05
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK-GLTPLYL 181
KI+ L+ GA + T + +T + AVE ++ ++ LL+ GA+ N G L+
Sbjct: 93 KIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQ 152
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNAS 241
+ + ++ + LL A D G + A + G ++ + L+ GA++N +
Sbjct: 153 ASFQENAEII-KLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALD 211
Query: 242 GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
TPL + A C LL G D + + N+ +Q+ + A
Sbjct: 212 KATPLFIAAQEGHTKCVELLLSSGADPDL--YCNEDSWQLPIHA 253
>AF156778-1|AAD41895.1| 518|Homo sapiens ASB-3 protein protein.
Length = 518
Score = 69.3 bits (162), Expect = 3e-11
Identities = 59/219 (26%), Positives = 94/219 (42%), Gaps = 5/219 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY---RTRD 141
G + + K KG + G P+ AA S + L L+N + +Y +T +
Sbjct: 21 GNVKVLRKLLKKGRSVDV-ADNRGWMPIHEAAYHNS-VECLQMLINADSSENYIKMKTFE 78
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G A+H A + + V+ LLE GA PN + TPL+L+V N +L L H
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
G+ + GW +HQA + + LL GA+ ++ G TPL V A + L
Sbjct: 139 NGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSIL 198
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ G + TP +A G+ E++ + +D
Sbjct: 199 ISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGAD 237
Score = 57.2 bits (132), Expect = 1e-07
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 5/183 (2%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY---KD 172
A + K+L L+ G +D G +H A NS+E ++ L+ +S NY K
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
+G L+L+ + ++ + LL A AT L+ + A NG + + LL +G
Sbjct: 77 FEGFCALHLAASQGHWKIV-QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 233 ADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
A++N + + G LH + + LL +G +KE + TP VA G L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 292 EVI 294
++
Sbjct: 196 SIL 198
Score = 48.8 bits (111), Expect = 5e-05
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK-GLTPLYL 181
KI+ L+ GA + T + +T + AVE ++ ++ LL+ GA+ N G L+
Sbjct: 93 KIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQ 152
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNAS 241
+ + ++ + LL A D G + A + G ++ + L+ GA++N +
Sbjct: 153 ASFQENAEII-KLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALD 211
Query: 242 GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
TPL + A C LL G D + + N+ +Q+ + A
Sbjct: 212 KATPLFIAAQEGHTKCVELLLSSGADPDL--YCNEDSWQLPIHA 253
>AC007883-1|AAY24350.1| 326|Homo sapiens unknown protein.
Length = 326
Score = 69.3 bits (162), Expect = 3e-11
Identities = 59/219 (26%), Positives = 94/219 (42%), Gaps = 5/219 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY---RTRD 141
G + + K KG + G P+ AA S + L L+N + +Y +T +
Sbjct: 21 GNVKVLRKLLKKGRSVDV-ADNRGWMPIHEAAYHNS-VECLQMLINADSSENYIKMKTFE 78
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G A+H A + + V+ LLE GA PN + TPL+L+V N +L L H
Sbjct: 79 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 138
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
G+ + GW +HQA + + LL GA+ ++ G TPL V A + L
Sbjct: 139 NGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSIL 198
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ G + TP +A G+ E++ + +D
Sbjct: 199 ISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGAD 237
Score = 57.2 bits (132), Expect = 1e-07
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 5/183 (2%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY---KD 172
A + K+L L+ G +D G +H A NS+E ++ L+ +S NY K
Sbjct: 17 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 76
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
+G L+L+ + ++ + LL A AT L+ + A NG + + LL +G
Sbjct: 77 FEGFCALHLAASQGHWKIV-QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 135
Query: 233 ADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
A++N + + G LH + + LL +G +KE + TP VA G L+
Sbjct: 136 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 195
Query: 292 EVI 294
++
Sbjct: 196 SIL 198
Score = 48.8 bits (111), Expect = 5e-05
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK-GLTPLYL 181
KI+ L+ GA + T + +T + AVE ++ ++ LL+ GA+ N G L+
Sbjct: 93 KIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQ 152
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNAS 241
+ + ++ + LL A D G + A + G ++ + L+ GA++N +
Sbjct: 153 ASFQENAEII-KLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALD 211
Query: 242 GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
TPL + A C LL G D + + N+ +Q+ + A
Sbjct: 212 KATPLFIAAQEGHTKCVELLLSSGADPDL--YCNEDSWQLPIHA 253
>AB209795-1|BAD93032.1| 340|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 340
Score = 69.3 bits (162), Expect = 3e-11
Identities = 59/219 (26%), Positives = 94/219 (42%), Gaps = 5/219 (2%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDY---RTRD 141
G + + K KG + G P+ AA S + L L+N + +Y +T +
Sbjct: 31 GNVKVLRKLLKKGRSVDV-ADNRGWMPIHEAAYHNS-VECLQMLINADSSENYIKMKTFE 88
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G A+H A + + V+ LLE GA PN + TPL+L+V N +L L H
Sbjct: 89 GFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANV 148
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
G+ + GW +HQA + + LL GA+ ++ G TPL V A + L
Sbjct: 149 NGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESLSIL 208
Query: 262 LFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ G + TP +A G+ E++ + +D
Sbjct: 209 ISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGAD 247
Score = 57.2 bits (132), Expect = 1e-07
Identities = 48/183 (26%), Positives = 82/183 (44%), Gaps = 5/183 (2%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY---KD 172
A + K+L L+ G +D G +H A NS+E ++ L+ +S NY K
Sbjct: 27 AAREGNVKVLRKLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 86
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
+G L+L+ + ++ + LL A AT L+ + A NG + + LL +G
Sbjct: 87 FEGFCALHLAASQGHWKIV-QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 145
Query: 233 ADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
A++N + + G LH + + LL +G +KE + TP VA G L+
Sbjct: 146 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 205
Query: 292 EVI 294
++
Sbjct: 206 SIL 208
Score = 48.8 bits (111), Expect = 5e-05
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK-GLTPLYL 181
KI+ L+ GA + T + +T + AVE ++ ++ LL+ GA+ N G L+
Sbjct: 103 KIVQILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQ 162
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNAS 241
+ + ++ + LL A D G + A + G ++ + L+ GA++N +
Sbjct: 163 ASFQENAEII-KLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALD 221
Query: 242 GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
TPL + A C LL G D + + N+ +Q+ + A
Sbjct: 222 KATPLFIAAQEGHTKCVELLLSSGADPDL--YCNEDSWQLPIHA 263
>DQ822519-1|ABG46944.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEA-VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L+YRT +G + +H ++ ++TL+ G P+ G T L+L+V K + L
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVY-KDNAELIT 118
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
+LLH A I G +H A G ++ D LL +GA++N ++A TPLH+ A
Sbjct: 119 SLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYG 178
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ R LL G D P +A G L++A+++
Sbjct: 179 HEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 7/214 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G+ I KGL P+ G T L +A K A+++ +L++ GA + G T
Sbjct: 79 GKKSHIRTLMLKGLRPS-RLTRNGFTALHLAV-YKDNAELITSLLHSGADIQQVGYGGLT 136
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A LEA LL+ GA+ N +D TPL+++ + + LL A +
Sbjct: 137 ALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQ-VTRLLLKFGADVNV 195
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYG--ADMNARNASGNTPLHVCAVNAQDSCARQLL 262
+ G + +H A G + L+ G AD+NA++ + PLH C+ + LL
Sbjct: 196 SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL 255
Query: 263 FRGCDKE--ALNFANQTPYQVAVIAGNLDLAEVI 294
+ + +N TP +A G ++A+ I
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEI 289
Score = 37.5 bits (83), Expect = 0.11
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 8/174 (4%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA ++ + T +H A + + LL+ GA N G PL+L+ + K
Sbjct: 153 LLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLA-SAKG 211
Query: 188 DPLLCETLLHD--HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR--NASGN 243
+ + L+ + A + A D + +H R G V +LL ++ N G+
Sbjct: 212 FLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGD 271
Query: 244 TPLHVCAVNAQDSCARQLL-FRGCDK-EALNFANQTPYQVAVIAG-NLDLAEVI 294
TPLH+ N + A++++ G + N ++T + A G ++DL + +
Sbjct: 272 TPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFL 325
Score = 36.3 bits (80), Expect = 0.26
Identities = 29/132 (21%), Positives = 49/132 (37%)
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
NY+ GL+ L+L TL+ G+ +H A + + L
Sbjct: 61 NYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSL 120
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
L GAD+ G T LH+ + A LL G + + TP +A G+
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHE 180
Query: 289 DLAEVIKNYKSD 300
+ ++ + +D
Sbjct: 181 QVTRLLLKFGAD 192
Score = 31.9 bits (69), Expect = 5.7
Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK--GLTPLYLSVTNKTDPLLCETLLHDH 199
G T +H A E K ++++ + + T + + T L + LL +
Sbjct: 270 GDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQN 329
Query: 200 A-TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMN 236
I G +H AC +G ++ V LL GADMN
Sbjct: 330 VININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
>BX640903-1|CAE45949.1| 714|Homo sapiens hypothetical protein
protein.
Length = 714
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEA-VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L+YRT +G + +H ++ ++TL+ G P+ G T L+L+V K + L
Sbjct: 178 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVY-KDNAELIT 236
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
+LLH A I G +H A G ++ D LL +GA++N ++A TPLH+ A
Sbjct: 237 SLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYG 296
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ R LL G D P +A G L++A+++
Sbjct: 297 HEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 337
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 7/214 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G+ I KGL P+ G T L +A K A+++ +L++ GA + G T
Sbjct: 197 GKKSHIRTLMLKGLRPS-RLTRNGFTALHLAV-YKDNAELITSLLHSGADIQQVGYGGLT 254
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A LEA LL+ GA+ N +D TPL+++ + + LL A +
Sbjct: 255 ALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQ-VTRLLLKFGADVNV 313
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYG--ADMNARNASGNTPLHVCAVNAQDSCARQLL 262
+ G + +H A G + L+ G AD+NA++ + PLH C+ + LL
Sbjct: 314 SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDMVKYLL 373
Query: 263 FRGCDKE--ALNFANQTPYQVAVIAGNLDLAEVI 294
+ + +N TP +A G ++A+ I
Sbjct: 374 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEI 407
Score = 37.9 bits (84), Expect = 0.087
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 8/174 (4%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA ++ + T +H A + + LL+ GA N G PL+L+ + K
Sbjct: 271 LLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLA-SAKG 329
Query: 188 DPLLCETLLHD--HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR--NASGN 243
+ + L+ + A + A D + +H R G V +LL ++ N G+
Sbjct: 330 FLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDMVKYLLQSDLEVQPHVVNIYGD 389
Query: 244 TPLHVCAVNAQDSCARQLL-FRGCDK-EALNFANQTPYQVAVIAG-NLDLAEVI 294
TPLH+ N + A++++ G + N ++T + A G ++DL + +
Sbjct: 390 TPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFL 443
Score = 36.3 bits (80), Expect = 0.26
Identities = 29/132 (21%), Positives = 49/132 (37%)
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
NY+ GL+ L+L TL+ G+ +H A + + L
Sbjct: 179 NYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSL 238
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
L GAD+ G T LH+ + A LL G + + TP +A G+
Sbjct: 239 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHE 298
Query: 289 DLAEVIKNYKSD 300
+ ++ + +D
Sbjct: 299 QVTRLLLKFGAD 310
>BX470253-1|CAI16293.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEA-VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L+YRT +G + +H ++ ++TL+ G P+ G T L+L+V K + L
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVY-KDNAELIT 118
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
+LLH A I G +H A G ++ D LL +GA++N ++A TPLH+ A
Sbjct: 119 SLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYG 178
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ R LL G D P +A G L++A+++
Sbjct: 179 HEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 7/214 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G+ I KGL P+ G T L +A K A+++ +L++ GA + G T
Sbjct: 79 GKKSHIRTLMLKGLRPS-RLTRNGFTALHLAV-YKDNAELITSLLHSGADIQQVGYGGLT 136
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A LEA LL+ GA+ N +D TPL+++ + + LL A +
Sbjct: 137 ALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQ-VTRLLLKFGADVNV 195
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYG--ADMNARNASGNTPLHVCAVNAQDSCARQLL 262
+ G + +H A G + L+ G AD+NA++ + PLH C+ + LL
Sbjct: 196 SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL 255
Query: 263 FRGCDKE--ALNFANQTPYQVAVIAGNLDLAEVI 294
+ + +N TP +A G ++A+ I
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEI 289
Score = 37.5 bits (83), Expect = 0.11
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 8/174 (4%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA ++ + T +H A + + LL+ GA N G PL+L+ + K
Sbjct: 153 LLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLA-SAKG 211
Query: 188 DPLLCETLLHD--HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR--NASGN 243
+ + L+ + A + A D + +H R G V +LL ++ N G+
Sbjct: 212 FLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGD 271
Query: 244 TPLHVCAVNAQDSCARQLL-FRGCDK-EALNFANQTPYQVAVIAG-NLDLAEVI 294
TPLH+ N + A++++ G + N ++T + A G ++DL + +
Sbjct: 272 TPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFL 325
Score = 36.3 bits (80), Expect = 0.26
Identities = 29/132 (21%), Positives = 49/132 (37%)
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
NY+ GL+ L+L TL+ G+ +H A + + L
Sbjct: 61 NYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSL 120
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
L GAD+ G T LH+ + A LL G + + TP +A G+
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHE 180
Query: 289 DLAEVIKNYKSD 300
+ ++ + +D
Sbjct: 181 QVTRLLLKFGAD 192
Score = 31.9 bits (69), Expect = 5.7
Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK--GLTPLYLSVTNKTDPLLCETLLHDH 199
G T +H A E K ++++ + + T + + T L + LL +
Sbjct: 270 GDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQN 329
Query: 200 A-TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMN 236
I G +H AC +G ++ V LL GADMN
Sbjct: 330 VININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
>BC117262-1|AAI17263.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEA-VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L+YRT +G + +H ++ ++TL+ G P+ G T L+L+V K + L
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVY-KDNAELIT 118
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
+LLH A I G +H A G ++ D LL +GA++N ++A TPLH+ A
Sbjct: 119 SLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYG 178
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ R LL G D P +A G L++A+++
Sbjct: 179 HEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 7/214 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G+ I KGL P+ G T L +A K A+++ +L++ GA + G T
Sbjct: 79 GKKSHIRTLMLKGLRPS-RLTRNGFTALHLAV-YKDNAELITSLLHSGADIQQVGYGGLT 136
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A LEA LL+ GA+ N +D TPL+++ + + LL A +
Sbjct: 137 ALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQ-VTRLLLKFGADVNV 195
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYG--ADMNARNASGNTPLHVCAVNAQDSCARQLL 262
+ G + +H A G + L+ G AD+NA++ + PLH C+ + LL
Sbjct: 196 SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL 255
Query: 263 FRGCDKE--ALNFANQTPYQVAVIAGNLDLAEVI 294
+ + +N TP +A G ++A+ I
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEI 289
Score = 37.5 bits (83), Expect = 0.11
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 8/174 (4%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA ++ + T +H A + + LL+ GA N G PL+L+ + K
Sbjct: 153 LLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLA-SAKG 211
Query: 188 DPLLCETLLHD--HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR--NASGN 243
+ + L+ + A + A D + +H R G V +LL ++ N G+
Sbjct: 212 FLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGD 271
Query: 244 TPLHVCAVNAQDSCARQLL-FRGCDK-EALNFANQTPYQVAVIAG-NLDLAEVI 294
TPLH+ N + A++++ G + N ++T + A G ++DL + +
Sbjct: 272 TPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFL 325
Score = 36.3 bits (80), Expect = 0.26
Identities = 29/132 (21%), Positives = 49/132 (37%)
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
NY+ GL+ L+L TL+ G+ +H A + + L
Sbjct: 61 NYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSL 120
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
L GAD+ G T LH+ + A LL G + + TP +A G+
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHE 180
Query: 289 DLAEVIKNYKSD 300
+ ++ + +D
Sbjct: 181 QVTRLLLKFGAD 192
Score = 31.9 bits (69), Expect = 5.7
Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK--GLTPLYLSVTNKTDPLLCETLLHDH 199
G T +H A E K ++++ + + T + + T L + LL +
Sbjct: 270 GDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQN 329
Query: 200 A-TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMN 236
I G +H AC +G ++ V LL GADMN
Sbjct: 330 VININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
>BC113539-1|AAI13540.1| 835|Homo sapiens TNNI3 interacting kinase
protein.
Length = 835
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEA-VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L+YRT +G + +H ++ ++TL+ G P+ G T L+L+V K + L
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVY-KDNAELIT 118
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
+LLH A I G +H A G ++ D LL +GA++N ++A TPLH+ A
Sbjct: 119 SLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYG 178
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ R LL G D P +A G L++A+++
Sbjct: 179 HEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 7/214 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G+ I KGL P+ G T L +A K A+++ +L++ GA + G T
Sbjct: 79 GKKSHIRTLMLKGLRPS-RLTRNGFTALHLAV-YKDNAELITSLLHSGADIQQVGYGGLT 136
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A LEA LL+ GA+ N +D TPL+++ + + LL A +
Sbjct: 137 ALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQ-VTRLLLKFGADVNV 195
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYG--ADMNARNASGNTPLHVCAVNAQDSCARQLL 262
+ G + +H A G + L+ G AD+NA++ + PLH C+ + LL
Sbjct: 196 SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL 255
Query: 263 FRGCDKE--ALNFANQTPYQVAVIAGNLDLAEVI 294
+ + +N TP +A G ++A+ I
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEI 289
Score = 37.5 bits (83), Expect = 0.11
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 8/174 (4%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA ++ + T +H A + + LL+ GA N G PL+L+ + K
Sbjct: 153 LLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLA-SAKG 211
Query: 188 DPLLCETLLHD--HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR--NASGN 243
+ + L+ + A + A D + +H R G V +LL ++ N G+
Sbjct: 212 FLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGD 271
Query: 244 TPLHVCAVNAQDSCARQLL-FRGCDK-EALNFANQTPYQVAVIAG-NLDLAEVI 294
TPLH+ N + A++++ G + N ++T + A G ++DL + +
Sbjct: 272 TPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFL 325
Score = 36.3 bits (80), Expect = 0.26
Identities = 29/132 (21%), Positives = 49/132 (37%)
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
NY+ GL+ L+L TL+ G+ +H A + + L
Sbjct: 61 NYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSL 120
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
L GAD+ G T LH+ + A LL G + + TP +A G+
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHE 180
Query: 289 DLAEVIKNYKSD 300
+ ++ + +D
Sbjct: 181 QVTRLLLKFGAD 192
Score = 31.9 bits (69), Expect = 5.7
Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK--GLTPLYLSVTNKTDPLLCETLLHDH 199
G T +H A E K ++++ + + T + + T L + LL +
Sbjct: 270 GDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQN 329
Query: 200 A-TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMN 236
I G +H AC +G ++ V LL GADMN
Sbjct: 330 VININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
>AY303691-1|AAP72030.1| 835|Homo sapiens cardiac ankyrin repeat
kinase protein.
Length = 835
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEA-VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L+YRT +G + +H ++ ++TL+ G P+ G T L+L+V K + L
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVY-KDNAELIT 118
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
+LLH A I G +H A G ++ D LL +GA++N ++A TPLH+ A
Sbjct: 119 SLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYG 178
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ R LL G D P +A G L++A+++
Sbjct: 179 HEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 7/214 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G+ I KGL P+ G T L +A K A+++ +L++ GA + G T
Sbjct: 79 GKKSHIRTLMLKGLRPS-RLTRNGFTALHLAV-YKDNAELITSLLHSGADIQQVGYGGLT 136
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A LEA LL+ GA+ N +D TPL+++ + + LL A +
Sbjct: 137 ALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQ-VTRLLLKFGADVNV 195
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYG--ADMNARNASGNTPLHVCAVNAQDSCARQLL 262
+ G + +H A G + L+ G AD+NA++ + PLH C+ + LL
Sbjct: 196 SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL 255
Query: 263 FRGCDKE--ALNFANQTPYQVAVIAGNLDLAEVI 294
+ + +N TP +A G ++A+ I
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEI 289
Score = 37.5 bits (83), Expect = 0.11
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 8/174 (4%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA ++ + T +H A + + LL+ GA N G PL+L+ + K
Sbjct: 153 LLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLA-SAKG 211
Query: 188 DPLLCETLLHD--HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR--NASGN 243
+ + L+ + A + A D + +H R G V +LL ++ N G+
Sbjct: 212 FLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGD 271
Query: 244 TPLHVCAVNAQDSCARQLL-FRGCDK-EALNFANQTPYQVAVIAG-NLDLAEVI 294
TPLH+ N + A++++ G + N ++T + A G ++DL + +
Sbjct: 272 TPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFL 325
Score = 36.3 bits (80), Expect = 0.26
Identities = 29/132 (21%), Positives = 49/132 (37%)
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
NY+ GL+ L+L TL+ G+ +H A + + L
Sbjct: 61 NYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSL 120
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
L GAD+ G T LH+ + A LL G + + TP +A G+
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHE 180
Query: 289 DLAEVIKNYKSD 300
+ ++ + +D
Sbjct: 181 QVTRLLLKFGAD 192
Score = 31.9 bits (69), Expect = 5.7
Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK--GLTPLYLSVTNKTDPLLCETLLHDH 199
G T +H A E K ++++ + + T + + T L + LL +
Sbjct: 270 GDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQN 329
Query: 200 A-TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMN 236
I G +H AC +G ++ V LL GADMN
Sbjct: 330 VININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
>AF116826-1|AAD29632.1| 835|Homo sapiens putative protein-tyrosine
kinase protein.
Length = 835
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEA-VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L+YRT +G + +H ++ ++TL+ G P+ G T L+L+V K + L
Sbjct: 60 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVY-KDNAELIT 118
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
+LLH A I G +H A G ++ D LL +GA++N ++A TPLH+ A
Sbjct: 119 SLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYG 178
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ R LL G D P +A G L++A+++
Sbjct: 179 HEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 219
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 7/214 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G+ I KGL P+ G T L +A K A+++ +L++ GA + G T
Sbjct: 79 GKKSHIRTLMLKGLRPS-RLTRNGFTALHLAV-YKDNAELITSLLHSGADIQQVGYGGLT 136
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A LEA LL+ GA+ N +D TPL+++ + + LL A +
Sbjct: 137 ALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQ-VTRLLLKFGADVNV 195
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYG--ADMNARNASGNTPLHVCAVNAQDSCARQLL 262
+ G + +H A G + L+ G AD+NA++ + PLH C+ + LL
Sbjct: 196 SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL 255
Query: 263 FRGCDKE--ALNFANQTPYQVAVIAGNLDLAEVI 294
+ + +N TP +A G ++A+ I
Sbjct: 256 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEI 289
Score = 37.5 bits (83), Expect = 0.11
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 8/174 (4%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA ++ + T +H A + + LL+ GA N G PL+L+ + K
Sbjct: 153 LLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLA-SAKG 211
Query: 188 DPLLCETLLHD--HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR--NASGN 243
+ + L+ + A + A D + +H R G V +LL ++ N G+
Sbjct: 212 FLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGD 271
Query: 244 TPLHVCAVNAQDSCARQLL-FRGCDK-EALNFANQTPYQVAVIAG-NLDLAEVI 294
TPLH+ N + A++++ G + N ++T + A G ++DL + +
Sbjct: 272 TPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFL 325
Score = 36.3 bits (80), Expect = 0.26
Identities = 29/132 (21%), Positives = 49/132 (37%)
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
NY+ GL+ L+L TL+ G+ +H A + + L
Sbjct: 61 NYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSL 120
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
L GAD+ G T LH+ + A LL G + + TP +A G+
Sbjct: 121 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHE 180
Query: 289 DLAEVIKNYKSD 300
+ ++ + +D
Sbjct: 181 QVTRLLLKFGAD 192
Score = 31.9 bits (69), Expect = 5.7
Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK--GLTPLYLSVTNKTDPLLCETLLHDH 199
G T +H A E K ++++ + + T + + T L + LL +
Sbjct: 270 GDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQN 329
Query: 200 A-TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMN 236
I G +H AC +G ++ V LL GADMN
Sbjct: 330 VININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 367
>AB208941-1|BAD92178.1| 941|Homo sapiens TNNI3 interacting kinase
variant protein.
Length = 941
Score = 68.9 bits (161), Expect = 4e-11
Identities = 48/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEA-VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L+YRT +G + +H ++ ++TL+ G P+ G T L+L+V K + L
Sbjct: 166 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVY-KDNAELIT 224
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
+LLH A I G +H A G ++ D LL +GA++N ++A TPLH+ A
Sbjct: 225 SLLHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYG 284
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ R LL G D P +A G L++A+++
Sbjct: 285 HEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 325
Score = 68.5 bits (160), Expect = 5e-11
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 7/214 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G+ I KGL P+ G T L +A K A+++ +L++ GA + G T
Sbjct: 185 GKKSHIRTLMLKGLRPS-RLTRNGFTALHLAV-YKDNAELITSLLHSGADIQQVGYGGLT 242
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A LEA LL+ GA+ N +D TPL+++ + + LL A +
Sbjct: 243 ALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQ-VTRLLLKFGADVNV 301
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYG--ADMNARNASGNTPLHVCAVNAQDSCARQLL 262
+ G + +H A G + L+ G AD+NA++ + PLH C+ + LL
Sbjct: 302 SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL 361
Query: 263 FRGCDKE--ALNFANQTPYQVAVIAGNLDLAEVI 294
+ + +N TP +A G ++A+ I
Sbjct: 362 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEI 395
Score = 37.5 bits (83), Expect = 0.11
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 8/174 (4%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA ++ + T +H A + + LL+ GA N G PL+L+ + K
Sbjct: 259 LLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLA-SAKG 317
Query: 188 DPLLCETLLHD--HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR--NASGN 243
+ + L+ + A + A D + +H R G V +LL ++ N G+
Sbjct: 318 FLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGD 377
Query: 244 TPLHVCAVNAQDSCARQLL-FRGCDK-EALNFANQTPYQVAVIAG-NLDLAEVI 294
TPLH+ N + A++++ G + N ++T + A G ++DL + +
Sbjct: 378 TPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFL 431
Score = 36.3 bits (80), Expect = 0.26
Identities = 29/132 (21%), Positives = 49/132 (37%)
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
NY+ GL+ L+L TL+ G+ +H A + + L
Sbjct: 167 NYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSL 226
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
L GAD+ G T LH+ + A LL G + + TP +A G+
Sbjct: 227 LHSGADIQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHE 286
Query: 289 DLAEVIKNYKSD 300
+ ++ + +D
Sbjct: 287 QVTRLLLKFGAD 298
Score = 31.9 bits (69), Expect = 5.7
Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK--GLTPLYLSVTNKTDPLLCETLLHDH 199
G T +H A E K ++++ + + T + + T L + LL +
Sbjct: 376 GDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQN 435
Query: 200 A-TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMN 236
I G +H AC +G ++ V LL GADMN
Sbjct: 436 VININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 473
>BC032865-1|AAH32865.1| 843|Homo sapiens TNNI3K protein protein.
Length = 843
Score = 68.5 bits (160), Expect = 5e-11
Identities = 47/161 (29%), Positives = 78/161 (48%), Gaps = 2/161 (1%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEA-VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCE 193
L+YRT +G + +H ++ ++TL+ G P+ G T L+L+V K + L
Sbjct: 161 LNYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVY-KDNAELIT 219
Query: 194 TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNA 253
+LLH A + G +H A G ++ D LL +GA++N ++A TPLH+ A
Sbjct: 220 SLLHSGADVQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYG 279
Query: 254 QDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+ R LL G D P +A G L++A+++
Sbjct: 280 HEQVTRLLLKFGADVNVSGEVGDRPLHLASAKGFLNIAKLL 320
Score = 68.1 bits (159), Expect = 7e-11
Identities = 58/214 (27%), Positives = 96/214 (44%), Gaps = 7/214 (3%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G+ I KGL P+ G T L +A K A+++ +L++ GA + G T
Sbjct: 180 GKKSHIRTLMLKGLRPS-RLTRNGFTALHLAV-YKDNAELITSLLHSGADVQQVGYGGLT 237
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A LEA LL+ GA+ N +D TPL+++ + + LL A +
Sbjct: 238 ALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHEQ-VTRLLLKFGADVNV 296
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYG--ADMNARNASGNTPLHVCAVNAQDSCARQLL 262
+ G + +H A G + L+ G AD+NA++ + PLH C+ + LL
Sbjct: 297 SGEVGDRPLHLASAKGFLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLL 356
Query: 263 FRGCDKE--ALNFANQTPYQVAVIAGNLDLAEVI 294
+ + +N TP +A G ++A+ I
Sbjct: 357 QSDLEVQPHVVNIYGDTPLHLACYNGKFEVAKEI 390
Score = 37.5 bits (83), Expect = 0.11
Identities = 41/174 (23%), Positives = 77/174 (44%), Gaps = 8/174 (4%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA ++ + T +H A + + LL+ GA N G PL+L+ + K
Sbjct: 254 LLQHGANVNIQDAVFFTPLHIAAYYGHEQVTRLLLKFGADVNVSGEVGDRPLHLA-SAKG 312
Query: 188 DPLLCETLLHD--HATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR--NASGN 243
+ + L+ + A + A D + +H R G V +LL ++ N G+
Sbjct: 313 FLNIAKLLMEEGSKADVNAQDNEDHVPLHFCSRFGHHDIVKYLLQSDLEVQPHVVNIYGD 372
Query: 244 TPLHVCAVNAQDSCARQLL-FRGCDK-EALNFANQTPYQVAVIAG-NLDLAEVI 294
TPLH+ N + A++++ G + N ++T + A G ++DL + +
Sbjct: 373 TPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFL 426
Score = 36.3 bits (80), Expect = 0.26
Identities = 29/132 (21%), Positives = 49/132 (37%)
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHL 228
NY+ GL+ L+L TL+ G+ +H A + + L
Sbjct: 162 NYRTENGLSLLHLCCICGGKKSHIRTLMLKGLRPSRLTRNGFTALHLAVYKDNAELITSL 221
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
L GAD+ G T LH+ + A LL G + + TP +A G+
Sbjct: 222 LHSGADVQQVGYGGLTALHIATIAGHLEAADVLLQHGANVNIQDAVFFTPLHIAAYYGHE 281
Query: 289 DLAEVIKNYKSD 300
+ ++ + +D
Sbjct: 282 QVTRLLLKFGAD 293
Score = 31.9 bits (69), Expect = 5.7
Identities = 25/98 (25%), Positives = 40/98 (40%), Gaps = 3/98 (3%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK--GLTPLYLSVTNKTDPLLCETLLHDH 199
G T +H A E K ++++ + + T + + T L + LL +
Sbjct: 371 GDTPLHLACYNGKFEVAKEIIQISGTESLTKENIFSETAFHSACTYGKSIDLVKFLLDQN 430
Query: 200 A-TIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMN 236
I G +H AC +G ++ V LL GADMN
Sbjct: 431 VININHQGRDGHTGLHSACYHGHIRLVQFLLDNGADMN 468
>BC016490-1|AAH16490.1| 1030|Homo sapiens MIB2 protein protein.
Length = 1030
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 571 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 629
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 630 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 689
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 690 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 749
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 750 AVQQAHVGLVPLL 762
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 536 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 595
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 596 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 635
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 540 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 598
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 599 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 657
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 658 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 717
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 718 LNNHREVAQIL 728
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 620 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 679
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 680 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 739
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 740 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 784
>AL691432-4|CAM12833.1| 919|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 919
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 460 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 518
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 519 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 578
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 579 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 638
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 639 AVQQAHVGLVPLL 651
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 425 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 484
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 485 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 524
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 429 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 487
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 488 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 546
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 547 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 606
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 607 LNNHREVAQIL 617
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 509 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 568
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 569 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 628
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 629 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 673
>AL691432-3|CAM12832.1| 753|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 753
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 431 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 489
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 490 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 549
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 550 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 609
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 610 AVQQAHVGLVPLL 622
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 396 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 455
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 456 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 495
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 400 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 458
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 459 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 517
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 518 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 577
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 578 LNNHREVAQIL 588
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 480 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 539
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 540 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 599
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 600 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 644
>AL691432-2|CAM12831.1| 999|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 999
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 540 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 598
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 599 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 658
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 659 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 718
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 719 AVQQAHVGLVPLL 731
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 505 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 564
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 565 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 604
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 509 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 567
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 568 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 626
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 627 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 686
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 687 LNNHREVAQIL 697
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 589 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 648
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 649 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 708
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 709 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 753
>AL691432-1|CAM12830.1| 948|Homo sapiens mindbomb homolog 2
(Drosophila) protein.
Length = 948
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 489 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 547
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 548 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 607
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 608 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 667
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 668 AVQQAHVGLVPLL 680
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 454 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 513
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 514 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 553
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 458 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 516
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 517 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 575
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 576 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 635
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 636 LNNHREVAQIL 646
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 538 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 597
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 598 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 657
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 658 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 702
>AK098785-1|BAC05413.1| 802|Homo sapiens protein ( Homo sapiens
cDNA FLJ25919 fis, clone CBR04994. ).
Length = 802
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 496 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 554
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 555 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 614
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 615 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 674
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 675 AVQQAHVGLVPLL 687
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 461 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 520
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 521 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 560
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 465 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 523
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 524 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 582
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 583 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 642
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 643 LNNHREVAQIL 653
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 545 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 604
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 605 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 664
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 665 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 709
>AK097106-1|BAC04952.1| 819|Homo sapiens protein ( Homo sapiens
cDNA FLJ39787 fis, clone SPLEN2002744, weakly similar to
ANKYRIN 2. ).
Length = 819
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 360 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 418
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 419 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 478
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 479 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 538
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 539 AVQQAHVGLVPLL 551
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 325 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 384
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 385 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 424
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 329 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 387
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 388 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 446
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 447 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 506
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 507 LNNHREVAQIL 517
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 409 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 468
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 469 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 528
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 529 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 573
>AK096295-1|BAC04752.1| 681|Homo sapiens protein ( Homo sapiens
cDNA FLJ38976 fis, clone NT2RI2004099, weakly similar to
ANKYRIN 2. ).
Length = 681
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 222 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 280
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 281 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 340
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 341 AVRKILARARQLVDAKEEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 400
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 401 AVQQAHVGLVPLL 413
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 187 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 246
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 247 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 286
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 191 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 249
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 250 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 308
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 309 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKEEDGFTALHLAA 368
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 369 LNNHREVAQIL 379
Score = 32.7 bits (71), Expect = 3.3
Identities = 35/165 (21%), Positives = 64/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 271 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 330
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A + G+ +H A N + L+ G D+N R
Sbjct: 331 HHASLKGHALAVRKILARARQLVDAKEEDGFTALHLAALNNHREVAQILIREGRCDVNVR 390
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 391 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 435
>AK095914-1|BAC04646.1| 681|Homo sapiens protein ( Homo sapiens
cDNA FLJ38595 fis, clone HEART2001773, weakly similar to
ANKYRIN 2. ).
Length = 681
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 222 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 280
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 281 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 340
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 341 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 400
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 401 AVQQAHVGLVPLL 413
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 187 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 246
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 247 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 286
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 191 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 249
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 250 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 308
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 309 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 368
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 369 LNNHREVAQIL 379
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 271 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 330
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 331 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 390
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 391 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 435
>AK091610-1|BAC03707.1| 645|Homo sapiens protein ( Homo sapiens
cDNA FLJ34291 fis, clone FEBRA2004620, weakly similar to
ANKYRIN 2. ).
Length = 645
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 186 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 244
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 245 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 304
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 305 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 364
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 365 AVQQAHVGLVPLL 377
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 151 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 210
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 211 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 250
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 155 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 213
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 214 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 272
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 273 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 332
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 333 LNNHREVAQIL 343
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 235 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 294
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 295 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 354
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 355 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 399
>AB097000-1|BAC77353.1| 999|Homo sapiens putative NFkB activating
protein protein.
Length = 999
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 540 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 598
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 599 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 658
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 659 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 718
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 719 AVQQAHVGLVPLL 731
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 505 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 564
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 565 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 604
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 509 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 567
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 568 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 626
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 627 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 686
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 687 LNNHREVAQIL 697
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 589 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 648
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 649 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 708
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 709 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 753
>AB076693-1|BAC00994.1| 1009|Homo sapiens skeletrophin gamma
protein.
Length = 1009
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 550 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 608
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 609 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 668
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 669 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 728
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 729 AVQQAHVGLVPLL 741
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 515 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 574
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 575 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 614
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 519 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 577
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 578 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 636
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 637 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 696
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 697 LNNHREVAQIL 707
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 599 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 658
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 659 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 718
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 719 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 763
>AB076692-1|BAC00993.1| 948|Homo sapiens skeletrophin beta protein.
Length = 948
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 489 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 547
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 548 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 607
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 608 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 667
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 668 AVQQAHVGLVPLL 680
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 454 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 513
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 514 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 553
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 458 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 516
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 517 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 575
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 576 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 635
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 636 LNNHREVAQIL 646
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 538 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 597
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 598 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 657
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 658 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 702
>AB076691-1|BAC00992.1| 999|Homo sapiens skeletrophin alpha
protein.
Length = 999
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 540 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 598
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 599 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 658
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 659 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 718
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 719 AVQQAHVGLVPLL 731
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 505 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 564
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 565 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 604
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 509 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 567
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 568 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 626
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 627 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 686
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 687 LNNHREVAQIL 697
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 589 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 648
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 649 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 708
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 709 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 753
>AB074480-1|BAB92950.1| 1013|Homo sapiens skeletrophin protein.
Length = 1013
Score = 68.5 bits (160), Expect = 5e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 554 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 612
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPL-LCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 613 CDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 672
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 673 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 732
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 733 AVQQAHVGLVPLL 745
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 519 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 578
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 579 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 618
Score = 39.5 bits (88), Expect = 0.028
Identities = 43/191 (22%), Positives = 79/191 (41%), Gaps = 6/191 (3%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 523 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 581
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL-VQHVD 226
+ + T L+++V ++ L + D +H A G +
Sbjct: 582 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGASGIV 640
Query: 227 HLL--FYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQVAV 283
+L D+ A N+ G T LH ++ R++L R +A T +A
Sbjct: 641 EVLTEVPNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAA 700
Query: 284 IAGNLDLAEVI 294
+ + ++A+++
Sbjct: 701 LNNHREVAQIL 711
Score = 31.5 bits (68), Expect = 7.5
Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + + V+ L E+ + +G T L
Sbjct: 603 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGASGIVEVLTEVPNIDVTATNSQGFTLL 662
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 663 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 722
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 723 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 767
>AK222715-1|BAD96435.1| 512|Homo sapiens ankyrin repeat and SOCS
box-containing protein 3 isoform a variant protein.
Length = 512
Score = 68.1 bits (159), Expect = 7e-11
Identities = 51/188 (27%), Positives = 83/188 (44%), Gaps = 3/188 (1%)
Query: 116 AGLKSPAKILIALVNGGALLDY---RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKD 172
A + + L L+N + +Y +T +G A+H A + + V+ LLE GA PN
Sbjct: 44 AAYHNSVECLQMLINADSSENYIKMKTFEGFCALHLAASQGHWKIVQILLEAGADPNATT 103
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
+ TPL+L+V N +L L H G+ + GW +HQA + + LL G
Sbjct: 104 LEETTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKG 163
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAE 292
A+ ++ G TPL V A + L+ G + TP +A G+ E
Sbjct: 164 ANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVE 223
Query: 293 VIKNYKSD 300
++ + +D
Sbjct: 224 LLLSSGAD 231
Score = 57.6 bits (133), Expect = 1e-07
Identities = 48/183 (26%), Positives = 83/183 (45%), Gaps = 5/183 (2%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY---KD 172
A ++ K+L L+ G +D G +H A NS+E ++ L+ +S NY K
Sbjct: 11 AAREANVKVLRQLLKKGRSVDVADNRGWMPIHEAAYHNSVECLQMLINADSSENYIKMKT 70
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
+G L+L+ + ++ + LL A AT L+ + A NG + + LL +G
Sbjct: 71 FEGFCALHLAASQGHWKIV-QILLEAGADPNATTLEETTPLFLAVENGQIDVLRLLLQHG 129
Query: 233 ADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
A++N + + G LH + + LL +G +KE + TP VA G L+
Sbjct: 130 ANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL 189
Query: 292 EVI 294
++
Sbjct: 190 SIL 192
Score = 51.2 bits (117), Expect = 9e-06
Identities = 54/204 (26%), Positives = 86/204 (42%), Gaps = 12/204 (5%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G DPN E TPL +A + + L +G + + G ++H+A + + E
Sbjct: 96 GADPNATTLEE-TTPLFLAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAE 154
Query: 157 AVKTLLELGASPNYKDGKGLTPLYLSVT-NKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+K LL GA+ +D G+TPL+++ K + L L+ A + L +
Sbjct: 155 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL--SILISSGANVNCQALDKATPLFI 212
Query: 216 ACRNGLVQHVDHLLFYGA--DMNARNASGNTPLHVCAVNAQDSCARQLL---FRGCDKEA 270
A + G + V+ LL GA D+ S P+H A L+ R CD
Sbjct: 213 AAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRACD-TG 271
Query: 271 LNFANQTPYQVAVIAGNLDLAEVI 294
LN +P AV G+ D E++
Sbjct: 272 LN--KVSPVYSAVFGGHEDCLEIL 293
>AB209433-1|BAD92670.1| 1031|Homo sapiens HLA-B associated
transcript 8 BAT8 isoform a variant protein.
Length = 1031
Score = 68.1 bits (159), Expect = 7e-11
Identities = 58/219 (26%), Positives = 92/219 (42%), Gaps = 9/219 (4%)
Query: 72 RANLRRFLEHVTHGQIDKITKACAKGLDPNFHC-QETGETPLTIAAGLKSPAKILIALVN 130
R + R+ V G++ K+ LDPNF Q++ TPL AA K +I L+
Sbjct: 462 RFHPRQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLH-AAAQKGSVEICHVLLQ 520
Query: 131 GGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPL 190
GA ++ + T + AV N LE + +++ G K+ G T L+ + +
Sbjct: 521 AGANINAVDKQQRTPLMEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEM 580
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMN-ARNAS------GN 243
+ L + A D GW + A + ++ + LL GAD+ N S N
Sbjct: 581 VSLLLSTGQVDVNAQDSGGWTPIIWAAEHKHIEVIRMLLTRGADVTLTDNVSERLVEEEN 640
Query: 244 TPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
LH + + A LL CD A+N+ TP +A
Sbjct: 641 ICLHWASFTGSAAIAEVLLNARCDLHAVNYHGDTPLHIA 679
Score = 59.7 bits (138), Expect = 2e-08
Identities = 51/180 (28%), Positives = 79/180 (43%), Gaps = 10/180 (5%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG-ASP 168
TPL + A + + ++ +V G + + DGST +H A + +LE V LL G
Sbjct: 534 TPL-MEAVVNNHLEVARYMVQRGGCVYSKEEDGSTCLHHAAKIGNLEMVSLLLSTGQVDV 592
Query: 169 NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEV-------HQACRNGL 221
N +D G TP+ + +K ++ LL A + TD + V H A G
Sbjct: 593 NAQDSGGWTPIIWAAEHKHIEVI-RMLLTRGADVTLTDNVSERLVEEENICLHWASFTGS 651
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ LL D++A N G+TPLH+ A + C L RG + E N T + +
Sbjct: 652 AAIAEVLLNARCDLHAVNYHGDTPLHIAARESYHDCVLLFLSRGANPELRNKEGDTAWDL 711
Score = 33.5 bits (73), Expect = 1.9
Identities = 22/83 (26%), Positives = 40/83 (48%), Gaps = 2/83 (2%)
Query: 211 QEVHQACRNGLVQHVDHLLFYGADMNARN--ASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
++++ + + G +Q V +L D N ++ S TPLH A LL G +
Sbjct: 466 RQLYLSVKQGELQKVILMLLDNLDPNFQSDQQSKRTPLHAAAQKGSVEICHVLLQAGANI 525
Query: 269 EALNFANQTPYQVAVIAGNLDLA 291
A++ +TP AV+ +L++A
Sbjct: 526 NAVDKQQRTPLMEAVVNNHLEVA 548
>BC037542-1|AAH37542.1| 999|Homo sapiens MIB2 protein protein.
Length = 999
Score = 67.7 bits (158), Expect = 9e-11
Identities = 56/193 (29%), Positives = 88/193 (45%), Gaps = 5/193 (2%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G T L AA P + L++ G D STA+H AV++ LE V+ L E G
Sbjct: 540 DEGNTALHYAALGNQPEATRV-LLSAGCRADAINSTQSTALHVAVQRGFLEVVRALCERG 598
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDP-LLCETLLH-DHATIGATDLQGWQEVHQACRNGLVQ 223
N D TPL+ +++ T + E L + + AT+ QG+ +H A G
Sbjct: 599 CDVNLPDAHSDTPLHSAISAGTGAGGIVEVLTEVPNIDVTATNSQGFTLLHHASLKGHAL 658
Query: 224 HVDHLLFYGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG-CDKEALNFANQTPYQV 281
V +L + +A+ G T LH+ A+N A+ L+ G CD N Q+P +
Sbjct: 659 AVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVRNRKLQSPLHL 718
Query: 282 AVIAGNLDLAEVI 294
AV ++ L ++
Sbjct: 719 AVQQAHVGLVPLL 731
Score = 45.2 bits (102), Expect = 6e-04
Identities = 31/100 (31%), Positives = 44/100 (44%)
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFR 264
T QG + A G V+ + LL A ++ + GNT LH A+ Q R LL
Sbjct: 505 TKNQGRTALQVAAYLGQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSA 564
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEIVP 304
GC +A+N T VAV G L++ + D +P
Sbjct: 565 GCRADAINSTQSTALHVAVQRGFLEVVRALCERGCDVNLP 604
Score = 39.1 bits (87), Expect = 0.038
Identities = 43/193 (22%), Positives = 81/193 (41%), Gaps = 10/193 (5%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G T L +AA L +++ L+ A +D +G+TA+H A N EA + LL G
Sbjct: 509 GRTALQVAAYL-GQVELIRLLLQARAGVDLPDDEGNTALHYAALGNQPEATRVLLSAGCR 567
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQAC-----RNGLV 222
+ + T L+++V ++ L + D +H A G+V
Sbjct: 568 ADAINSTQSTALHVAVQRGFLEVV-RALCERGCDVNLPDAHSDTPLHSAISAGTGAGGIV 626
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCD-KEALNFANQTPYQV 281
+ + + D+ A N+ G T LH ++ R++L R +A T +
Sbjct: 627 EVLTEV--PNIDVTATNSQGFTLLHHASLKGHALAVRKILARARQLVDAKKEDGFTALHL 684
Query: 282 AVIAGNLDLAEVI 294
A + + ++A+++
Sbjct: 685 AALNNHREVAQIL 697
Score = 31.1 bits (67), Expect = 9.9
Identities = 35/165 (21%), Positives = 62/165 (37%), Gaps = 4/165 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEA--VKTLLEL-GASPNYKDGKGLTPL 179
+++ AL G ++ T +H A+ + V+ L E+ + +G T L
Sbjct: 589 EVVRALCERGCDVNLPDAHSDTPLHSAISAGTGAGGIVEVLTEVPNIDVTATNSQGFTLL 648
Query: 180 YLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG-ADMNAR 238
+ + + + L + A G+ +H A N + L+ G D+N R
Sbjct: 649 HHASLKGHALAVRKILARARQLVDAKKEDGFTALHLAALNNHREVAQILIREGRCDVNVR 708
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
N +PLH+ A L+ GC A + T VA+
Sbjct: 709 NRKLQSPLHLAVQQAHVGLVPLLVDAGCSVNAEDEEGDTALHVAL 753
>BC063581-1|AAH63581.1| 274|Homo sapiens ankyrin repeat and SOCS
box-containing 7 protein.
Length = 274
Score = 67.3 bits (157), Expect = 1e-10
Identities = 58/195 (29%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 97 GLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNS 154
G DP G T L AA G A++++ +++ ++ DG T +H A
Sbjct: 70 GADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGR 129
Query: 155 LEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVH 214
V+ LLE A + KG TPL L++ + C +L DH D+Q +
Sbjct: 130 DSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSS--CVKILLDHNA--NIDIQNGFLLR 185
Query: 215 QACRNGLVQHVDHLLFYGADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNF 273
A + L GAD N R G TPLH+ A+ CAR L G D N+
Sbjct: 186 YAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNY 245
Query: 274 ANQTPYQVAV-IAGN 287
QTP V++ I+G+
Sbjct: 246 EGQTPLAVSISISGS 260
Score = 58.8 bits (136), Expect = 4e-08
Identities = 43/155 (27%), Positives = 73/155 (47%), Gaps = 3/155 (1%)
Query: 149 AVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
AV + V+ +LE G SPN +D G T L+ S + + L H +
Sbjct: 21 AVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIG 80
Query: 209 GWQEVHQACRNGLVQHVDHLLF--YGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG 265
G+ +H A +G + +L Y +D+ NA++ G TPLHV A +DS R LL
Sbjct: 81 GFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFK 140
Query: 266 CDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ + L+ TP Q+A+I +++ ++ ++
Sbjct: 141 AEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNAN 175
Score = 40.3 bits (90), Expect = 0.016
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
+LH H +LQ ++ A G V V +L G N R+A+G T LH A +
Sbjct: 1 MLHHHCRRNP-ELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGK 59
Query: 255 DSCARQLLFRGCDKEALN-FANQTPYQVAVIAGNLDLAEVI--KNYKSDEI 302
+ C R L G D + T A + G +A ++ Y+SD I
Sbjct: 60 ERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDII 110
>AK222974-1|BAD96694.1| 274|Homo sapiens ankyrin repeat and SOCS
box-containing protein 7 isoform 1 variant protein.
Length = 274
Score = 67.3 bits (157), Expect = 1e-10
Identities = 58/195 (29%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 97 GLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNS 154
G DP G T L AA G A++++ +++ ++ DG T +H A
Sbjct: 70 GADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGR 129
Query: 155 LEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVH 214
V+ LLE A + KG TPL L++ + C +L DH D+Q +
Sbjct: 130 DSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSS--CVKILLDHNA--NIDIQNGFLLR 185
Query: 215 QACRNGLVQHVDHLLFYGADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNF 273
A + L GAD N R G TPLH+ A+ CAR L G D N+
Sbjct: 186 YAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNY 245
Query: 274 ANQTPYQVAV-IAGN 287
QTP V++ I+G+
Sbjct: 246 EGQTPLAVSISISGS 260
Score = 58.8 bits (136), Expect = 4e-08
Identities = 43/155 (27%), Positives = 73/155 (47%), Gaps = 3/155 (1%)
Query: 149 AVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
AV + V+ +LE G SPN +D G T L+ S + + L H +
Sbjct: 21 AVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIG 80
Query: 209 GWQEVHQACRNGLVQHVDHLLF--YGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG 265
G+ +H A +G + +L Y +D+ NA++ G TPLHV A +DS R LL
Sbjct: 81 GFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFK 140
Query: 266 CDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ + L+ TP Q+A+I +++ ++ ++
Sbjct: 141 AEVDPLSDKGTTPLQLAIIREKSSCVKILLDHNAN 175
Score = 40.3 bits (90), Expect = 0.016
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
+LH H +LQ ++ A G V V +L G N R+A+G T LH A +
Sbjct: 1 MLHHHCRRNP-ELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGK 59
Query: 255 DSCARQLLFRGCDKEALN-FANQTPYQVAVIAGNLDLAEVI--KNYKSDEI 302
+ C R L G D + T A + G +A ++ Y+SD I
Sbjct: 60 ERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDII 110
>AK222958-1|BAD96678.1| 274|Homo sapiens ankyrin repeat and SOCS
box-containing protein 7 isoform 1 variant protein.
Length = 274
Score = 67.3 bits (157), Expect = 1e-10
Identities = 58/195 (29%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 97 GLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNS 154
G DP G T L AA G A++++ +++ ++ DG T +H A
Sbjct: 70 GADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGR 129
Query: 155 LEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVH 214
V+ LLE A + KG TPL L++ + C +L DH D+Q +
Sbjct: 130 DSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSS--CVKILLDHNA--NIDIQNGFLLR 185
Query: 215 QACRNGLVQHVDHLLFYGADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNF 273
A + L GAD N R G TPLH+ A+ CAR L G D N+
Sbjct: 186 YAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNY 245
Query: 274 ANQTPYQVAV-IAGN 287
QTP V++ I+G+
Sbjct: 246 EGQTPLAVSISISGS 260
Score = 58.8 bits (136), Expect = 4e-08
Identities = 43/155 (27%), Positives = 73/155 (47%), Gaps = 3/155 (1%)
Query: 149 AVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
AV + V+ +LE G SPN +D G T L+ S + + L H +
Sbjct: 21 AVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIG 80
Query: 209 GWQEVHQACRNGLVQHVDHLLF--YGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG 265
G+ +H A +G + +L Y +D+ NA++ G TPLHV A +DS R LL
Sbjct: 81 GFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFK 140
Query: 266 CDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ + L+ TP Q+A+I +++ ++ ++
Sbjct: 141 AEVDPLSDKGTTPLQLAIIREKSSCVKILLDHNAN 175
Score = 40.3 bits (90), Expect = 0.016
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
+LH H +LQ ++ A G V V +L G N R+A+G T LH A +
Sbjct: 1 MLHHHCRRNP-ELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGK 59
Query: 255 DSCARQLLFRGCDKEALN-FANQTPYQVAVIAGNLDLAEVI--KNYKSDEI 302
+ C R L G D + T A + G +A ++ Y+SD I
Sbjct: 60 ERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDII 110
>AK026204-1|BAB15392.1| 274|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22551 fis, clone HSI00804. ).
Length = 274
Score = 67.3 bits (157), Expect = 1e-10
Identities = 58/195 (29%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 97 GLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNS 154
G DP G T L AA G A++++ +++ ++ DG T +H A
Sbjct: 70 GADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGR 129
Query: 155 LEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVH 214
V+ LLE A + KG TPL L++ + C +L DH D+Q +
Sbjct: 130 DSFVRLLLEFKAEVDPLSDKGTTPLQLAIIREKSS--CVKILLDHNA--NIDIQNGFLLR 185
Query: 215 QACRNGLVQHVDHLLFYGADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNF 273
A + L GAD N R G TPLH+ A+ CAR L G D N+
Sbjct: 186 YAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNY 245
Query: 274 ANQTPYQVAV-IAGN 287
QTP V++ I+G+
Sbjct: 246 EGQTPLAVSISISGS 260
Score = 58.8 bits (136), Expect = 4e-08
Identities = 43/155 (27%), Positives = 73/155 (47%), Gaps = 3/155 (1%)
Query: 149 AVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
AV + V+ +LE G SPN +D G T L+ S + + L H +
Sbjct: 21 AVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIG 80
Query: 209 GWQEVHQACRNGLVQHVDHLLF--YGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG 265
G+ +H A +G + +L Y +D+ NA++ G TPLHV A +DS R LL
Sbjct: 81 GFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFK 140
Query: 266 CDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ + L+ TP Q+A+I +++ ++ ++
Sbjct: 141 AEVDPLSDKGTTPLQLAIIREKSSCVKILLDHNAN 175
Score = 40.3 bits (90), Expect = 0.016
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
+LH H +LQ ++ A G V V +L G N R+A+G T LH A +
Sbjct: 1 MLHHHCRRNP-ELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGK 59
Query: 255 DSCARQLLFRGCDKEALN-FANQTPYQVAVIAGNLDLAEVI--KNYKSDEI 302
+ C R L G D + T A + G +A ++ Y+SD I
Sbjct: 60 ERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDII 110
>AF451994-1|AAP97683.1| 318|Homo sapiens ankyrin repeat-containing
SOCS box protein 7 protein.
Length = 318
Score = 67.3 bits (157), Expect = 1e-10
Identities = 58/195 (29%), Positives = 84/195 (43%), Gaps = 8/195 (4%)
Query: 97 GLDPNFHCQETGETPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNS 154
G DP G T L AA G A++++ +++ ++ DG T +H A
Sbjct: 70 GADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGR 129
Query: 155 LEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVH 214
V+ LLE A + KG TPL L++ + C +L DH D+Q +
Sbjct: 130 DSFVRLLLEFKAEVDPLSDKGTTPLQLAIIRERSS--CVKILLDHNA--NIDIQNGFLLR 185
Query: 215 QACRNGLVQHVDHLLFYGADMN-ARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNF 273
A + L GAD N R G TPLH+ A+ CAR L G D N+
Sbjct: 186 YAVIKSNHSYCRMFLQRGADTNLGRLEDGQTPLHLSALRDDVLCARMLYNYGADTNTRNY 245
Query: 274 ANQTPYQVAV-IAGN 287
QTP V++ I+G+
Sbjct: 246 EGQTPLAVSISISGS 260
Score = 58.8 bits (136), Expect = 4e-08
Identities = 43/155 (27%), Positives = 73/155 (47%), Gaps = 3/155 (1%)
Query: 149 AVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
AV + V+ +LE G SPN +D G T L+ S + + L H +
Sbjct: 21 AVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGKERCVRVFLEHGADPTVKDLIG 80
Query: 209 GWQEVHQACRNGLVQHVDHLLF--YGADM-NARNASGNTPLHVCAVNAQDSCARQLLFRG 265
G+ +H A +G + +L Y +D+ NA++ G TPLHV A +DS R LL
Sbjct: 81 GFTALHYAAMHGRARIARLMLESEYRSDIINAKSNDGWTPLHVAAHYGRDSFVRLLLEFK 140
Query: 266 CDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ + L+ TP Q+A+I +++ ++ ++
Sbjct: 141 AEVDPLSDKGTTPLQLAIIRERSSCVKILLDHNAN 175
Score = 40.3 bits (90), Expect = 0.016
Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 4/111 (3%)
Query: 195 LLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
+LH H +LQ ++ A G V V +L G N R+A+G T LH A +
Sbjct: 1 MLHHHCRRNP-ELQEELQIQAAVAAGDVHTVRKMLEQGYSPNGRDANGWTLLHFSAARGK 59
Query: 255 DSCARQLLFRGCDKEALN-FANQTPYQVAVIAGNLDLAEVI--KNYKSDEI 302
+ C R L G D + T A + G +A ++ Y+SD I
Sbjct: 60 ERCVRVFLEHGADPTVKDLIGGFTALHYAAMHGRARIARLMLESEYRSDII 110
>U76638-1|AAB38316.1| 777|Homo sapiens BRCA1-associated RING domain
protein protein.
Length = 777
Score = 66.9 bits (156), Expect = 2e-10
Identities = 41/109 (37%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
R G T +H A K + +V+ LL+ G+ PN KD G TPL+ N + E LL
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLH-EACNHGHLKVVELLLQ 482
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPL 246
A + T Q +H A +NG V V LL YGA NA N G P+
Sbjct: 483 HKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPV 531
Score = 52.4 bits (120), Expect = 4e-06
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 5/136 (3%)
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
S++ +R V +S A+K L + N++ G T L+++ + K D E LL + +
Sbjct: 400 SSSSYRQV-MSSPSAMKLLPNMAVKRNHR---GETLLHIA-SIKGDIPSVEYLLQNGSDP 454
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D GW +H+AC +G ++ V+ LL + A +N ++PLH A N + LL
Sbjct: 455 NVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLL 514
Query: 263 FRGCDKEALNFANQTP 278
G + A+N P
Sbjct: 515 SYGASRNAVNIFGLRP 530
Score = 39.1 bits (87), Expect = 0.038
Identities = 22/85 (25%), Positives = 40/85 (47%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A G + V++LL G+D N ++ +G TPLH + LL
Sbjct: 432 LHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTG 491
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNY 297
+ N +P A G++D+ +++ +Y
Sbjct: 492 YQNDSPLHDAAKNGHVDIVKLLLSY 516
Score = 34.7 bits (76), Expect = 0.81
Identities = 18/62 (29%), Positives = 28/62 (45%)
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RN G T LH+ ++ LL G D + A TP A G+L + E++ +
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQH 483
Query: 298 KS 299
K+
Sbjct: 484 KA 485
>BC126426-1|AAI26427.1| 777|Homo sapiens BRCA1 associated RING
domain 1 protein.
Length = 777
Score = 66.9 bits (156), Expect = 2e-10
Identities = 41/109 (37%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
R G T +H A K + +V+ LL+ G+ PN KD G TPL+ N + E LL
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLH-EACNHGHLKVVELLLQ 482
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPL 246
A + T Q +H A +NG V V LL YGA NA N G P+
Sbjct: 483 HKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPV 531
Score = 52.4 bits (120), Expect = 4e-06
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 5/136 (3%)
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
S++ +R V +S A+K L + N++ G T L+++ + K D E LL + +
Sbjct: 400 SSSSYRRV-MSSPSAMKLLPNMAVKRNHR---GETLLHIA-SIKGDIPSVEYLLQNGSDP 454
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D GW +H+AC +G ++ V+ LL + A +N ++PLH A N + LL
Sbjct: 455 NVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLL 514
Query: 263 FRGCDKEALNFANQTP 278
G + A+N P
Sbjct: 515 SYGASRNAVNIFGLRP 530
Score = 39.1 bits (87), Expect = 0.038
Identities = 22/85 (25%), Positives = 40/85 (47%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A G + V++LL G+D N ++ +G TPLH + LL
Sbjct: 432 LHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTG 491
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNY 297
+ N +P A G++D+ +++ +Y
Sbjct: 492 YQNDSPLHDAAKNGHVDIVKLLLSY 516
Score = 34.7 bits (76), Expect = 0.81
Identities = 18/62 (29%), Positives = 28/62 (45%)
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RN G T LH+ ++ LL G D + A TP A G+L + E++ +
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQH 483
Query: 298 KS 299
K+
Sbjct: 484 KA 485
>AK223409-1|BAD97129.1| 777|Homo sapiens BRCA1 associated RING
domain 1 variant protein.
Length = 777
Score = 66.9 bits (156), Expect = 2e-10
Identities = 41/109 (37%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
R G T +H A K + +V+ LL+ G+ PN KD G TPL+ N + E LL
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLH-EACNHGHLKVVELLLQ 482
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPL 246
A + T Q +H A +NG V V LL YGA NA N G P+
Sbjct: 483 HKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPV 531
Score = 52.4 bits (120), Expect = 4e-06
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 5/136 (3%)
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
S++ +R V +S A+K L + N++ G T L+++ + K D E LL + +
Sbjct: 400 SSSSYRRV-MSSPSAMKLLPNMAVKRNHR---GETLLHIA-SIKGDIPSVEYLLQNGSDP 454
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D GW +H+AC +G ++ V+ LL + A +N ++PLH A N + LL
Sbjct: 455 NVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLL 514
Query: 263 FRGCDKEALNFANQTP 278
G + A+N P
Sbjct: 515 SYGASRNAVNIFGLRP 530
Score = 39.1 bits (87), Expect = 0.038
Identities = 22/85 (25%), Positives = 40/85 (47%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A G + V++LL G+D N ++ +G TPLH + LL
Sbjct: 432 LHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTG 491
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNY 297
+ N +P A G++D+ +++ +Y
Sbjct: 492 YQNDSPLHDAAKNGHVDIVKLLLSY 516
Score = 34.7 bits (76), Expect = 0.81
Identities = 18/62 (29%), Positives = 28/62 (45%)
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RN G T LH+ ++ LL G D + A TP A G+L + E++ +
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQH 483
Query: 298 KS 299
K+
Sbjct: 484 KA 485
>AF038042-1|AAB99978.1| 777|Homo sapiens BRCA1-associated RING
domain protein protein.
Length = 777
Score = 66.9 bits (156), Expect = 2e-10
Identities = 41/109 (37%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
R G T +H A K + +V+ LL+ G+ PN KD G TPL+ N + E LL
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLH-EACNHGHLKVVELLLQ 482
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPL 246
A + T Q +H A +NG V V LL YGA NA N G P+
Sbjct: 483 HKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPV 531
Score = 52.4 bits (120), Expect = 4e-06
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 5/136 (3%)
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
S++ +R V +S A+K L + N++ G T L+++ + K D E LL + +
Sbjct: 400 SSSSYRRV-MSSPSAMKLLPNMAVKRNHR---GETLLHIA-SIKGDIPSVEYLLQNGSDP 454
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D GW +H+AC +G ++ V+ LL + A +N ++PLH A N + LL
Sbjct: 455 NVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLL 514
Query: 263 FRGCDKEALNFANQTP 278
G + A+N P
Sbjct: 515 SYGASRNAVNIFGLRP 530
Score = 39.1 bits (87), Expect = 0.038
Identities = 22/85 (25%), Positives = 40/85 (47%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A G + V++LL G+D N ++ +G TPLH + LL
Sbjct: 432 LHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTG 491
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNY 297
+ N +P A G++D+ +++ +Y
Sbjct: 492 YQNDSPLHDAAKNGHVDIVKLLLSY 516
Score = 34.7 bits (76), Expect = 0.81
Identities = 18/62 (29%), Positives = 28/62 (45%)
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RN G T LH+ ++ LL G D + A TP A G+L + E++ +
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQH 483
Query: 298 KS 299
K+
Sbjct: 484 KA 485
>AC016708-1|AAX93130.1| 777|Homo sapiens unknown protein.
Length = 777
Score = 66.9 bits (156), Expect = 2e-10
Identities = 41/109 (37%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
R G T +H A K + +V+ LL+ G+ PN KD G TPL+ N + E LL
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLH-EACNHGHLKVVELLLQ 482
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPL 246
A + T Q +H A +NG V V LL YGA NA N G P+
Sbjct: 483 HKALVNTTGYQNDSPLHDAAKNGHVDIVKLLLSYGASRNAVNIFGLRPV 531
Score = 52.4 bits (120), Expect = 4e-06
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 5/136 (3%)
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
S++ +R V +S A+K L + N++ G T L+++ + K D E LL + +
Sbjct: 400 SSSSYRRV-MSSPSAMKLLPNMAVKRNHR---GETLLHIA-SIKGDIPSVEYLLQNGSDP 454
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D GW +H+AC +G ++ V+ LL + A +N ++PLH A N + LL
Sbjct: 455 NVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHVDIVKLLL 514
Query: 263 FRGCDKEALNFANQTP 278
G + A+N P
Sbjct: 515 SYGASRNAVNIFGLRP 530
Score = 39.1 bits (87), Expect = 0.038
Identities = 22/85 (25%), Positives = 40/85 (47%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A G + V++LL G+D N ++ +G TPLH + LL
Sbjct: 432 LHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTG 491
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNY 297
+ N +P A G++D+ +++ +Y
Sbjct: 492 YQNDSPLHDAAKNGHVDIVKLLLSY 516
Score = 34.7 bits (76), Expect = 0.81
Identities = 18/62 (29%), Positives = 28/62 (45%)
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RN G T LH+ ++ LL G D + A TP A G+L + E++ +
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQH 483
Query: 298 KS 299
K+
Sbjct: 484 KA 485
>AY367056-1|AAQ72374.1| 520|Homo sapiens KIAA0379-like protein
protein.
Length = 520
Score = 66.5 bits (155), Expect = 2e-10
Identities = 52/198 (26%), Positives = 89/198 (44%), Gaps = 9/198 (4%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G+TPL ++ L + +L+N GA +D + + G TA+HR E V LL+ GA
Sbjct: 120 GQTPLMLSV-LNGHTDCVYSLLNKGANVDAKDKWGRTALHRGAVTGHEECVDALLQHGAK 178
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA----TDLQGWQEVHQACRNGLVQ 223
+D +G TP++LS +L LL A++ A D G+ +H AC NG
Sbjct: 179 CLLRDSRGRTPIHLSAACGHIGVL-GALLQSAASMDANPATADNHGYTALHWACYNGHET 237
Query: 224 HVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL--FRGCDKEALNFANQTPYQV 281
V+ LL + +PLH +N + A L+ A + +TP
Sbjct: 238 CVE-LLLEQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHA 296
Query: 282 AVIAGNLDLAEVIKNYKS 299
A +++ +++ ++ +
Sbjct: 297 AAFTDHVECLQLLLSHNA 314
Score = 54.0 bits (124), Expect = 1e-06
Identities = 48/176 (27%), Positives = 77/176 (43%), Gaps = 6/176 (3%)
Query: 122 AKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYL 181
A++LI + G ++++ G T +H A + +E ++ LL A N D G TPL +
Sbjct: 271 AEMLIDTL-GASIVNATDSKGRTPLHAAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMM 329
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGAD---MNAR 238
+ N + + A + D +H AC G +L D +NA
Sbjct: 330 AAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINAT 389
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
NA+ TPLHV A N ++LL +G A++ TP A N D+A+ +
Sbjct: 390 NAALQTPLHVAARNGLTMVVQELLGKGASVLAVDENGYTP--ALACAPNKDVADCL 443
Score = 52.8 bits (121), Expect = 3e-06
Identities = 45/148 (30%), Positives = 65/148 (43%), Gaps = 4/148 (2%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLE-LGA 166
G TPL AA + L L++ A ++ G T + A E V+ L+ A
Sbjct: 290 GRTPLH-AAAFTDHVECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASA 348
Query: 167 SPNYKDGKGLTPLYLSVT--NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
+D T L+L+ + ++T LL + D I AT+ +H A RNGL
Sbjct: 349 ELTLQDNSKNTALHLACSKGHETSALLILEKITDRNLINATNAALQTPLHVAARNGLTMV 408
Query: 225 VDHLLFYGADMNARNASGNTPLHVCAVN 252
V LL GA + A + +G TP CA N
Sbjct: 409 VQELLGKGASVLAVDENGYTPALACAPN 436
Score = 50.8 bits (116), Expect = 1e-05
Identities = 55/227 (24%), Positives = 92/227 (40%), Gaps = 10/227 (4%)
Query: 82 VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRD 141
V +G D + KG + + + G T L A + + + AL+ GA R
Sbjct: 128 VLNGHTDCVYSLLNKGANVDAK-DKWGRTALHRGA-VTGHEECVDALLQHGAKCLLRDSR 185
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGAS----PNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
G T +H + + + LL+ AS P D G T L+ + N + C LL
Sbjct: 186 GRTPIHLSAACGHIGVLGALLQSAASMDANPATADNHGYTALHWACYNGHET--CVELLL 243
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLL-FYGADM-NARNASGNTPLHVCAVNAQD 255
+ T+ + +H A N + L+ GA + NA ++ G TPLH A
Sbjct: 244 EQEVFQKTEGNAFSPLHCAVINDNEGAAEMLIDTLGASIVNATDSKGRTPLHAAAFTDHV 303
Query: 256 SCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDEI 302
C + LL +++ +TP +A G + E++ + S E+
Sbjct: 304 ECLQLLLSHNAQVNSVDSTGKTPLMMAAENGQTNTVEMLVSSASAEL 350
Score = 46.8 bits (106), Expect = 2e-04
Identities = 50/191 (26%), Positives = 81/191 (42%), Gaps = 8/191 (4%)
Query: 110 TPLTIAA--GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
TP+ AA G ++LI +D + +G T + +V + V +LL GA+
Sbjct: 86 TPIHAAATNGHSECLRLLIGNAEPQNAVDIQDGNGQTPLMLSVLNGHTDCVYSLLNKGAN 145
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+ KD G T L+ + + + LL A D +G +H + G + +
Sbjct: 146 VDAKDKWGRTALHRGAVTGHEECV-DALLQHGAKCLLRDSRGRTPIHLSAACGHIGVLGA 204
Query: 228 LLFYGADMNARNAS----GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
LL A M+A A+ G T LH N ++C LL + ++ A +P AV
Sbjct: 205 LLQSAASMDANPATADNHGYTALHWACYNGHETCVELLLEQEVFQKTEGNA-FSPLHCAV 263
Query: 284 IAGNLDLAEVI 294
I N AE++
Sbjct: 264 INDNEGAAEML 274
Score = 34.3 bits (75), Expect = 1.1
Identities = 21/83 (25%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A +G Q ++ L+ D++ RN+SG TPL + A C L+ +G +
Sbjct: 21 LHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVECVDVLINQGASILVKD 80
Query: 273 F-ANQTPYQVAVIAGNLDLAEVI 294
+ +TP A G+ + ++
Sbjct: 81 YILKRTPIHAAATNGHSECLRLL 103
Score = 31.9 bits (69), Expect = 5.7
Identities = 27/107 (25%), Positives = 48/107 (44%), Gaps = 4/107 (3%)
Query: 107 TGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGA 166
TG+TPL +AA + + + + A L + +TA+H A K + +LE
Sbjct: 322 TGKTPLMMAAENGQTNTVEMLVSSASAELTLQDNSKNTALHLACSKGHETSALLILEKIT 381
Query: 167 SPNYKDGKGL---TPLYLSVTNKTDPLLCETLLHDHATIGATDLQGW 210
N + TPL+++ N ++ + LL A++ A D G+
Sbjct: 382 DRNLINATNAALQTPLHVAARNGL-TMVVQELLGKGASVLAVDENGY 427
Score = 31.5 bits (68), Expect = 7.5
Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Query: 232 GADM--NARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLD 289
G DM ++ N + +PLH+ A + L+ D + N + +TP +A G+++
Sbjct: 5 GTDMLSDSDNRATISPLHLAAYHGHHQALEVLVQSLLDLDVRNSSGRTPLDLAAFKGHVE 64
Query: 290 LAEVIKNYKSDEIV 303
+V+ N + +V
Sbjct: 65 CVDVLINQGASILV 78
>U05681-1|AAC51348.1| 368|Homo sapiens B-cell leukemia/lymphoma 3
protein.
Length = 368
Score = 66.1 bits (154), Expect = 3e-10
Identities = 57/180 (31%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
+TPL +A P+ + + LV GA R G TA H A E S ++ LL+ A+P
Sbjct: 87 QTPLHLAVITTLPSVVRL-LVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLD-SAAP 144
Query: 169 NYKDGK-----GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ-GWQEVHQACRNGLV 222
D + GLT L+++V + + + LL A I A D++ G + A N +
Sbjct: 145 GTLDLEARNYDGLTALHVAVNTECQETV-QLLLERGADIDAVDIKSGRSPLIHAVENNSL 203
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
V LL +GA++NA+ SG++ LH + R L+ G D N N TP VA
Sbjct: 204 SMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVA 263
Score = 63.3 bits (147), Expect = 2e-09
Identities = 50/145 (34%), Positives = 72/145 (49%), Gaps = 5/145 (3%)
Query: 108 GETPLTIAAGLKSPA--KILIALVNGGAL-LDYRTRDGSTAMHRAVEKNSLEAVKTLLEL 164
G+T +A +SP + L+ G L L+ R DG TA+H AV E V+ LLE
Sbjct: 119 GQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTECQETVQLLLER 178
Query: 165 GASPNYKDGK-GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQ 223
GA + D K G +PL +V N + ++ + LL A + A G +H A GL+
Sbjct: 179 GADIDAVDIKSGRSPLIHAVENNSLSMV-QLLLQHGANVNAQMYSGSSALHSASGRGLLP 237
Query: 224 HVDHLLFYGADMNARNASGNTPLHV 248
V L+ GAD + +N +TPL V
Sbjct: 238 LVRTLVRSGADSSLKNCHNDTPLMV 262
Score = 56.4 bits (130), Expect = 2e-07
Identities = 58/204 (28%), Positives = 85/204 (41%), Gaps = 11/204 (5%)
Query: 106 ETGETPLTIAA---GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL 162
E G+TPL IA L + +++ GG LD T +H AV V+ L+
Sbjct: 47 EDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLV 106
Query: 163 ELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ-----GWQEVHQAC 217
GASP D G T +L+ +++ C L D A G DL+ G +H A
Sbjct: 107 TAGASPMALDRHGQTAAHLACEHRSP--TCLRALLDSAAPGTLDLEARNYDGLTALHVAV 164
Query: 218 RNGLVQHVDHLLFYGADMNARN-ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQ 276
+ V LL GAD++A + SG +PL N S + LL G + A ++
Sbjct: 165 NTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYSGS 224
Query: 277 TPYQVAVIAGNLDLAEVIKNYKSD 300
+ A G L L + +D
Sbjct: 225 SALHSASGRGLLPLVRTLVRSGAD 248
Score = 37.1 bits (82), Expect = 0.15
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
++G +PL A S + + + L+ GA ++ + GS+A+H A + L V+TL+ G
Sbjct: 188 KSGRSPLIHAVENNSLSMVQL-LLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSG 246
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLL 191
A + K+ TPL ++ + + +L
Sbjct: 247 ADSSLKNCHNDTPLMVARSRRVIDIL 272
>M69043-1|AAA16489.1| 317|Homo sapiens MAD3 protein.
Length = 317
Score = 66.1 bits (154), Expect = 3e-10
Identities = 49/156 (31%), Positives = 80/156 (51%), Gaps = 8/156 (5%)
Query: 133 ALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN---KTDP 189
A L+++ T +H AV N E + LL G P +D +G TPL+L+ +
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVG 161
Query: 190 LLCE--TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN-ASGNTPL 246
+L + T H H+ + AT+ G +H A +G + V+ L+ GAD+NA+ +G T L
Sbjct: 162 VLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTAL 221
Query: 247 HVCAVNAQDSCARQLLFR-GCDKEALNFANQTPYQV 281
H+ AV+ Q+ LL + G D + + +PYQ+
Sbjct: 222 HL-AVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQL 256
Score = 40.3 bits (90), Expect = 0.016
Identities = 21/56 (37%), Positives = 27/56 (48%)
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
A +N +N TPLH+ + Q A LL GCD E +F TP +A G L
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCL 157
>M31732-1|AAA51815.1| 446|Homo sapiens BCL3 protein.
Length = 446
Score = 66.1 bits (154), Expect = 3e-10
Identities = 57/180 (31%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
+TPL +A P+ + + LV GA R G TA H A E S ++ LL+ A+P
Sbjct: 165 QTPLHLAVITTLPSVVRL-LVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLD-SAAP 222
Query: 169 NYKDGK-----GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ-GWQEVHQACRNGLV 222
D + GLT L+++V + + + LL A I A D++ G + A N +
Sbjct: 223 GTLDLEARNYDGLTALHVAVNTECQETV-QLLLERGADIDAVDIKSGRSPLIHAVENNSL 281
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
V LL +GA++NA+ SG++ LH + R L+ G D N N TP VA
Sbjct: 282 SMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVA 341
Score = 63.3 bits (147), Expect = 2e-09
Identities = 50/145 (34%), Positives = 72/145 (49%), Gaps = 5/145 (3%)
Query: 108 GETPLTIAAGLKSPA--KILIALVNGGAL-LDYRTRDGSTAMHRAVEKNSLEAVKTLLEL 164
G+T +A +SP + L+ G L L+ R DG TA+H AV E V+ LLE
Sbjct: 197 GQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTECQETVQLLLER 256
Query: 165 GASPNYKDGK-GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQ 223
GA + D K G +PL +V N + ++ + LL A + A G +H A GL+
Sbjct: 257 GADIDAVDIKSGRSPLIHAVENNSLSMV-QLLLQHGANVNAQMYSGSSALHSASGRGLLP 315
Query: 224 HVDHLLFYGADMNARNASGNTPLHV 248
V L+ GAD + +N +TPL V
Sbjct: 316 LVRTLVRSGADSSLKNCHNDTPLMV 340
Score = 56.4 bits (130), Expect = 2e-07
Identities = 58/204 (28%), Positives = 85/204 (41%), Gaps = 11/204 (5%)
Query: 106 ETGETPLTIAA---GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL 162
E G+TPL IA L + +++ GG LD T +H AV V+ L+
Sbjct: 125 EDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLV 184
Query: 163 ELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ-----GWQEVHQAC 217
GASP D G T +L+ +++ C L D A G DL+ G +H A
Sbjct: 185 TAGASPMALDRHGQTAAHLACEHRSP--TCLRALLDSAAPGTLDLEARNYDGLTALHVAV 242
Query: 218 RNGLVQHVDHLLFYGADMNARN-ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQ 276
+ V LL GAD++A + SG +PL N S + LL G + A ++
Sbjct: 243 NTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYSGS 302
Query: 277 TPYQVAVIAGNLDLAEVIKNYKSD 300
+ A G L L + +D
Sbjct: 303 SALHSASGRGLLPLVRTLVRSGAD 326
Score = 37.1 bits (82), Expect = 0.15
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
++G +PL A S + + + L+ GA ++ + GS+A+H A + L V+TL+ G
Sbjct: 266 KSGRSPLIHAVENNSLSMVQL-LLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSG 324
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLL 191
A + K+ TPL ++ + + +L
Sbjct: 325 ADSSLKNCHNDTPLMVARSRRVIDIL 350
>BT007091-1|AAP35754.1| 317|Homo sapiens nuclear factor of kappa
light polypeptide gene enhancer in B-cells inhibitor, a
protein.
Length = 317
Score = 66.1 bits (154), Expect = 3e-10
Identities = 49/156 (31%), Positives = 80/156 (51%), Gaps = 8/156 (5%)
Query: 133 ALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN---KTDP 189
A L+++ T +H AV N E + LL G P +D +G TPL+L+ +
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVG 161
Query: 190 LLCE--TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN-ASGNTPL 246
+L + T H H+ + AT+ G +H A +G + V+ L+ GAD+NA+ +G T L
Sbjct: 162 VLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTAL 221
Query: 247 HVCAVNAQDSCARQLLFR-GCDKEALNFANQTPYQV 281
H+ AV+ Q+ LL + G D + + +PYQ+
Sbjct: 222 HL-AVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQL 256
Score = 40.3 bits (90), Expect = 0.016
Identities = 21/56 (37%), Positives = 27/56 (48%)
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
A +N +N TPLH+ + Q A LL GCD E +F TP +A G L
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCL 157
>BC064993-1|AAH64993.1| 446|Homo sapiens B-cell CLL/lymphoma 3
protein.
Length = 446
Score = 66.1 bits (154), Expect = 3e-10
Identities = 57/180 (31%), Positives = 85/180 (47%), Gaps = 9/180 (5%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
+TPL +A P+ + + LV GA R G TA H A E S ++ LL+ A+P
Sbjct: 165 QTPLHLAVITTLPSVVRL-LVTAGASPMALDRHGQTAAHLACEHRSPTCLRALLD-SAAP 222
Query: 169 NYKDGK-----GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ-GWQEVHQACRNGLV 222
D + GLT L+++V + + + LL A I A D++ G + A N +
Sbjct: 223 GTLDLEARNYDGLTALHVAVNTECQETV-QLLLERGADIDAVDIKSGRSPLIHAVENNSL 281
Query: 223 QHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
V LL +GA++NA+ SG++ LH + R L+ G D N N TP VA
Sbjct: 282 SMVQLLLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSGADSSLKNCHNDTPLMVA 341
Score = 63.3 bits (147), Expect = 2e-09
Identities = 50/145 (34%), Positives = 72/145 (49%), Gaps = 5/145 (3%)
Query: 108 GETPLTIAAGLKSPA--KILIALVNGGAL-LDYRTRDGSTAMHRAVEKNSLEAVKTLLEL 164
G+T +A +SP + L+ G L L+ R DG TA+H AV E V+ LLE
Sbjct: 197 GQTAAHLACEHRSPTCLRALLDSAAPGTLDLEARNYDGLTALHVAVNTECQETVQLLLER 256
Query: 165 GASPNYKDGK-GLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQ 223
GA + D K G +PL +V N + ++ + LL A + A G +H A GL+
Sbjct: 257 GADIDAVDIKSGRSPLIHAVENNSLSMV-QLLLQHGANVNAQMYSGSSALHSASGRGLLP 315
Query: 224 HVDHLLFYGADMNARNASGNTPLHV 248
V L+ GAD + +N +TPL V
Sbjct: 316 LVRTLVRSGADSSLKNCHNDTPLMV 340
Score = 56.4 bits (130), Expect = 2e-07
Identities = 58/204 (28%), Positives = 85/204 (41%), Gaps = 11/204 (5%)
Query: 106 ETGETPLTIAA---GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL 162
E G+TPL IA L + +++ GG LD T +H AV V+ L+
Sbjct: 125 EDGDTPLHIAVVQGNLPAVHRLVNLFQQGGRELDIYNNLRQTPLHLAVITTLPSVVRLLV 184
Query: 163 ELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ-----GWQEVHQAC 217
GASP D G T +L+ +++ C L D A G DL+ G +H A
Sbjct: 185 TAGASPMALDRHGQTAAHLACEHRSP--TCLRALLDSAAPGTLDLEARNYDGLTALHVAV 242
Query: 218 RNGLVQHVDHLLFYGADMNARN-ASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQ 276
+ V LL GAD++A + SG +PL N S + LL G + A ++
Sbjct: 243 NTECQETVQLLLERGADIDAVDIKSGRSPLIHAVENNSLSMVQLLLQHGANVNAQMYSGS 302
Query: 277 TPYQVAVIAGNLDLAEVIKNYKSD 300
+ A G L L + +D
Sbjct: 303 SALHSASGRGLLPLVRTLVRSGAD 326
Score = 37.1 bits (82), Expect = 0.15
Identities = 24/86 (27%), Positives = 46/86 (53%), Gaps = 1/86 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
++G +PL A S + + + L+ GA ++ + GS+A+H A + L V+TL+ G
Sbjct: 266 KSGRSPLIHAVENNSLSMVQL-LLQHGANVNAQMYSGSSALHSASGRGLLPLVRTLVRSG 324
Query: 166 ASPNYKDGKGLTPLYLSVTNKTDPLL 191
A + K+ TPL ++ + + +L
Sbjct: 325 ADSSLKNCHNDTPLMVARSRRVIDIL 350
>BC004983-1|AAH04983.1| 317|Homo sapiens nuclear factor of kappa
light polypeptide gene enhancer in B-cells inhibitor, a
protein.
Length = 317
Score = 66.1 bits (154), Expect = 3e-10
Identities = 49/156 (31%), Positives = 80/156 (51%), Gaps = 8/156 (5%)
Query: 133 ALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN---KTDP 189
A L+++ T +H AV N E + LL G P +D +G TPL+L+ +
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVG 161
Query: 190 LLCE--TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN-ASGNTPL 246
+L + T H H+ + AT+ G +H A +G + V+ L+ GAD+NA+ +G T L
Sbjct: 162 VLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTAL 221
Query: 247 HVCAVNAQDSCARQLLFR-GCDKEALNFANQTPYQV 281
H+ AV+ Q+ LL + G D + + +PYQ+
Sbjct: 222 HL-AVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQL 256
Score = 40.3 bits (90), Expect = 0.016
Identities = 21/56 (37%), Positives = 27/56 (48%)
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
A +N +N TPLH+ + Q A LL GCD E +F TP +A G L
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCL 157
>BC002601-1|AAH02601.1| 317|Homo sapiens nuclear factor of kappa
light polypeptide gene enhancer in B-cells inhibitor, a
protein.
Length = 317
Score = 66.1 bits (154), Expect = 3e-10
Identities = 49/156 (31%), Positives = 80/156 (51%), Gaps = 8/156 (5%)
Query: 133 ALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN---KTDP 189
A L+++ T +H AV N E + LL G P +D +G TPL+L+ +
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVG 161
Query: 190 LLCE--TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN-ASGNTPL 246
+L + T H H+ + AT+ G +H A +G + V+ L+ GAD+NA+ +G T L
Sbjct: 162 VLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTAL 221
Query: 247 HVCAVNAQDSCARQLLFR-GCDKEALNFANQTPYQV 281
H+ AV+ Q+ LL + G D + + +PYQ+
Sbjct: 222 HL-AVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQL 256
Score = 40.3 bits (90), Expect = 0.016
Identities = 21/56 (37%), Positives = 27/56 (48%)
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
A +N +N TPLH+ + Q A LL GCD E +F TP +A G L
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCL 157
>AY496422-1|AAR29599.1| 317|Homo sapiens nuclear factor of kappa
light polypeptide gene enhancer in B-cells inhibitor, a
protein.
Length = 317
Score = 66.1 bits (154), Expect = 3e-10
Identities = 49/156 (31%), Positives = 80/156 (51%), Gaps = 8/156 (5%)
Query: 133 ALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN---KTDP 189
A L+++ T +H AV N E + LL G P +D +G TPL+L+ +
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVG 161
Query: 190 LLCE--TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN-ASGNTPL 246
+L + T H H+ + AT+ G +H A +G + V+ L+ GAD+NA+ +G T L
Sbjct: 162 VLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTAL 221
Query: 247 HVCAVNAQDSCARQLLFR-GCDKEALNFANQTPYQV 281
H+ AV+ Q+ LL + G D + + +PYQ+
Sbjct: 222 HL-AVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQL 256
Score = 40.3 bits (90), Expect = 0.016
Identities = 21/56 (37%), Positives = 27/56 (48%)
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
A +N +N TPLH+ + Q A LL GCD E +F TP +A G L
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCL 157
>AY033600-1|AAK51149.1| 317|Homo sapiens NFKBIA protein.
Length = 317
Score = 66.1 bits (154), Expect = 3e-10
Identities = 49/156 (31%), Positives = 80/156 (51%), Gaps = 8/156 (5%)
Query: 133 ALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN---KTDP 189
A L+++ T +H AV N E + LL G P +D +G TPL+L+ +
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVG 161
Query: 190 LLCE--TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN-ASGNTPL 246
+L + T H H+ + AT+ G +H A +G + V+ L+ GAD+NA+ +G T L
Sbjct: 162 VLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTAL 221
Query: 247 HVCAVNAQDSCARQLLFR-GCDKEALNFANQTPYQV 281
H+ AV+ Q+ LL + G D + + +PYQ+
Sbjct: 222 HL-AVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQL 256
Score = 40.3 bits (90), Expect = 0.016
Identities = 21/56 (37%), Positives = 27/56 (48%)
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
A +N +N TPLH+ + Q A LL GCD E +F TP +A G L
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCL 157
>AJ249294-1|CAB65556.2| 317|Homo sapiens IkBa protein.
Length = 317
Score = 66.1 bits (154), Expect = 3e-10
Identities = 49/156 (31%), Positives = 80/156 (51%), Gaps = 8/156 (5%)
Query: 133 ALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTN---KTDP 189
A L+++ T +H AV N E + LL G P +D +G TPL+L+ +
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCLASVG 161
Query: 190 LLCE--TLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARN-ASGNTPL 246
+L + T H H+ + AT+ G +H A +G + V+ L+ GAD+NA+ +G T L
Sbjct: 162 VLTQSCTTPHLHSILKATNYNGHTCLHLASIHGYLGIVELLVSLGADVNAQEPCNGRTAL 221
Query: 247 HVCAVNAQDSCARQLLFR-GCDKEALNFANQTPYQV 281
H+ AV+ Q+ LL + G D + + +PYQ+
Sbjct: 222 HL-AVDLQNPDLVSLLLKCGADVNRVTYQGYSPYQL 256
Score = 40.3 bits (90), Expect = 0.016
Identities = 21/56 (37%), Positives = 27/56 (48%)
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNL 288
A +N +N TPLH+ + Q A LL GCD E +F TP +A G L
Sbjct: 102 AFLNFQNNLQQTPLHLAVITNQPEIAEALLGAGCDPELRDFRGNTPLHLACEQGCL 157
>BC126428-1|AAI26429.1| 777|Homo sapiens BRCA1 associated RING
domain 1 protein.
Length = 777
Score = 65.7 bits (153), Expect = 4e-10
Identities = 40/109 (36%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
R G T +H A K + +V+ LL+ G+ PN KD G TPL+ N + E LL
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLH-EACNHGHLKVVELLLQ 482
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPL 246
A + T Q +H A +NG + V LL YGA NA N G P+
Sbjct: 483 HKALVNTTGYQNDSPLHDAAKNGHMDIVKLLLSYGASRNAVNIFGLRPV 531
Score = 52.4 bits (120), Expect = 4e-06
Identities = 39/136 (28%), Positives = 66/136 (48%), Gaps = 5/136 (3%)
Query: 143 STAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATI 202
S++ +R V +S A+K L + N++ G T L+++ + K D E LL + +
Sbjct: 400 SSSSYRRV-MSSPSAMKLLPNMAVKRNHR---GETLLHIA-SIKGDIPSVEYLLQNGSDP 454
Query: 203 GATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D GW +H+AC +G ++ V+ LL + A +N ++PLH A N + LL
Sbjct: 455 NVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTGYQNDSPLHDAAKNGHMDIVKLLL 514
Query: 263 FRGCDKEALNFANQTP 278
G + A+N P
Sbjct: 515 SYGASRNAVNIFGLRP 530
Score = 39.5 bits (88), Expect = 0.028
Identities = 22/85 (25%), Positives = 40/85 (47%)
Query: 213 VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALN 272
+H A G + V++LL G+D N ++ +G TPLH + LL
Sbjct: 432 LHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQHKALVNTTG 491
Query: 273 FANQTPYQVAVIAGNLDLAEVIKNY 297
+ N +P A G++D+ +++ +Y
Sbjct: 492 YQNDSPLHDAAKNGHMDIVKLLLSY 516
Score = 34.7 bits (76), Expect = 0.81
Identities = 18/62 (29%), Positives = 28/62 (45%)
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
RN G T LH+ ++ LL G D + A TP A G+L + E++ +
Sbjct: 424 RNHRGETLLHIASIKGDIPSVEYLLQNGSDPNVKDHAGWTPLHEACNHGHLKVVELLLQH 483
Query: 298 KS 299
K+
Sbjct: 484 KA 485
>AY317139-1|AAP84319.1| 983|Homo sapiens RAI14 isoform protein.
Length = 983
Score = 65.7 bits (153), Expect = 4e-10
Identities = 56/209 (26%), Positives = 89/209 (42%), Gaps = 6/209 (2%)
Query: 61 LDEKTLKALHSRANLRRFLEHVTHGQIDKITKACAK-GLDPNFHCQETGETPLTIAAGLK 119
L K K N R L+ V +G +K+ K G H E G+T +AA K
Sbjct: 9 LSAKEKKTNEWNKNDDRLLQAVENGDAEKVASLLGKKGASATKHDSE-GKTAFHLAAA-K 66
Query: 120 SPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPL 179
+ L ++ G + + G +A+H A + + E ++ LL+ D G T L
Sbjct: 67 GHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTAL 126
Query: 180 YLSVTNKTDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNAR 238
+ + L +L +H + I DL G + A +NG + LL +GAD+N+R
Sbjct: 127 HYAAAQGC--LQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSR 184
Query: 239 NASGNTPLHVCAVNAQDSCARQLLFRGCD 267
N SG T L + + L+ +G D
Sbjct: 185 NKSGRTALMLACEIGSSNAVEALIKKGAD 213
Score = 62.9 bits (146), Expect = 3e-09
Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 1/172 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
K+ L GA +G TA H A K +E ++ ++ G +D G + L+L+
Sbjct: 37 KVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLA 96
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
N + LL + D G +H A G +Q V L + + +N ++ G
Sbjct: 97 AKNSHHECI-RKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDG 155
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
N PL + N LL G D + N + +T +A G+ + E +
Sbjct: 156 NIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEAL 207
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 3/163 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ + G+D TG + L +AA S + + L+ + G T
Sbjct: 67 GHVECLRVMITHGVDVTAQ-DTTGHSALHLAAK-NSHHECIRKLLQSKCPAESVDSSGKT 124
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A + L+AV+ L E + N KD G PL L+V N + C LL A + +
Sbjct: 125 ALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEI-CHFLLDHGADVNS 183
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ G + AC G V+ L+ GAD+N ++ G LH
Sbjct: 184 RNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALH 226
Score = 54.4 bits (125), Expect = 9e-07
Identities = 26/94 (27%), Positives = 50/94 (53%)
Query: 206 DLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRG 265
D +G H A G V+ + ++ +G D+ A++ +G++ LH+ A N+ C R+LL
Sbjct: 53 DSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSK 112
Query: 266 CDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
C E+++ + +T A G L +++ +KS
Sbjct: 113 CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKS 146
>AC017035-2|AAY15060.1| 394|Homo sapiens unknown protein.
Length = 394
Score = 65.7 bits (153), Expect = 4e-10
Identities = 59/201 (29%), Positives = 88/201 (43%), Gaps = 11/201 (5%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTR-DGSTAMHRAVEKNSLEAVKTLLEL 164
E G T L +AA K + + AL+N GA + + T +H +V ++ LLE+
Sbjct: 48 EKGRTALDLAA-FKGHTECVEALINQGASIFVKDNVTKRTPLHASVINGHTLCLRLLLEI 106
Query: 165 GASP---NYKDGKGLTPLYLSVT-NKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNG 220
+P + KD KG TPL L+V D + LL A + D+ G +H+ G
Sbjct: 107 ADNPEAVDVKDAKGQTPLMLAVAYGHIDAV--SLLLEKEANVDTVDILGCTALHRGIMTG 164
Query: 221 LVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFA-NQ--T 277
+ V LL + +++ G TPLH A + +LL +E F NQ T
Sbjct: 165 HEECVQMLLEQEVSILCKDSRGRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYT 224
Query: 278 PYQVAVIAGNLDLAEVIKNYK 298
P A GN + EV+ K
Sbjct: 225 PLHWACYNGNENCIEVLLEQK 245
Score = 55.6 bits (128), Expect = 4e-07
Identities = 59/211 (27%), Positives = 90/211 (42%), Gaps = 9/211 (4%)
Query: 109 ETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASP 168
++PL +AA + L L+ LD R G TA+ A K E V+ L+ GAS
Sbjct: 18 KSPLHLAA-YNGHHQALEVLLQSLVDLDIRDEKGRTALDLAAFKGHTECVEALINQGASI 76
Query: 169 NYKDG-KGLTPLYLSVTNKTDPLLCETLLHDHA----TIGATDLQGWQEVHQACRNGLVQ 223
KD TPL+ SV N LC LL + A + D +G + A G +
Sbjct: 77 FVKDNVTKRTPLHASVIN--GHTLCLRLLLEIADNPEAVDVKDAKGQTPLMLAVAYGHID 134
Query: 224 HVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
V LL A+++ + G T LH + + C + LL + + +TP A
Sbjct: 135 AVSLLLEKEANVDTVDILGCTALHRGIMTGHEECVQMLLEQEVSILCKDSRGRTPLHYAA 194
Query: 284 IAGNLD-LAEVIKNYKSDEIVPFRGPPRYNP 313
G+ L+E+++ S+E F+ Y P
Sbjct: 195 ARGHATWLSELLQMALSEEDCCFKDNQGYTP 225
Score = 48.0 bits (109), Expect = 8e-05
Identities = 34/107 (31%), Positives = 50/107 (46%), Gaps = 4/107 (3%)
Query: 171 KDGKGLTPLYLSVTNKTDPLLCETLLHDH-ATIGATDLQGWQEVHQACRNGLVQHVDHLL 229
+D KG TPL+ + D + C LL H A + A D G + A NG VD L+
Sbjct: 285 RDDKGRTPLHAAAF--ADHVECLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILV 342
Query: 230 FYG-ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
AD+ ++ NTPLH+ + CA +L + D+ +N N
Sbjct: 343 NSAQADLTVKDKDLNTPLHLACSKGHEKCALLILDKIQDESLINEKN 389
Score = 37.9 bits (84), Expect = 0.087
Identities = 36/160 (22%), Positives = 63/160 (39%), Gaps = 7/160 (4%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPN---YKDGKGLTPLYLSVTNKTDPLLCETLLHD 198
G T +H A + + LL++ S +KD +G TPL+ + N + C +L +
Sbjct: 186 GRTPLHYAAARGHATWLSELLQMALSEEDCCFKDNQGYTPLHWACYNGNEN--CIEVLLE 243
Query: 199 HATIGATDLQGWQEVHQACRNGLVQHVDHLL--FYGADMNARNASGNTPLHVCAVNAQDS 256
+ +H A N LL + ++ R+ G TPLH A
Sbjct: 244 QKCFRKFIGNPFTPLHCAIINDHGNCASLLLGAIDSSIVSCRDDKGRTPLHAAAFADHVE 303
Query: 257 CARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
C + LL A++ + +T +A G +++ N
Sbjct: 304 CLQLLLRHSAPVNAVDNSGKTALMMAAENGQAGAVDILVN 343
>AJ278120-1|CAB92314.1| 1101|Homo sapiens putative ankyrin-repeat
containing protein protein.
Length = 1101
Score = 65.3 bits (152), Expect = 5e-10
Identities = 54/204 (26%), Positives = 88/204 (43%), Gaps = 3/204 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
GET LT AAG + ++ L+ GA + R G+ + V + + V LL GA
Sbjct: 135 GETALTAAAG-RGKLEVCRLLLEQGAAVAQPNRRGAVPLFSTVRQGHWQIVDLLLTHGAD 193
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N D +G TPL ++ + + + LL A+I D +G + AC G + V
Sbjct: 194 VNMADKQGRTPLMMAASEGHLGTV-DFLLAQGASIALMDKEGLTALSWACLKGHLSVVRS 252
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
L+ GA + + +G TPL + A + L+ G E ++++ P AV N
Sbjct: 253 LVDNGAATDHADKNGRTPLDLAAFYGDAEVVQFLVDHGAMIEHVDYSGMRPLDRAVGCPN 312
Query: 288 LD-LAEVIKNYKSDEIVPFRGPPR 310
+ ++K D + PR
Sbjct: 313 TSVVVTLLKKRSQDRLSDVXSRPR 336
>Y10601-1|CAA71610.1| 1119|Homo sapiens ankyrin-like protein
protein.
Length = 1119
Score = 64.9 bits (151), Expect = 7e-10
Identities = 47/160 (29%), Positives = 76/160 (47%), Gaps = 8/160 (5%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G+T +H AVEKN +E+VK LL GA+PN ++ + PL+++V + ++ L H
Sbjct: 98 GNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTID 157
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
+ G V AC + + LL GA N G P+H A + C +
Sbjct: 158 VNLEGENGNTAVIIACTTNNSEALQILLNKGAKPCKSNKWGCFPIHQAAFSGSKECMEII 217
Query: 262 L----FRGCDKEA-LNFANQ---TPYQVAVIAGNLDLAEV 293
L G ++ +NF N TP +AV G+L++ ++
Sbjct: 218 LRFGEEHGYSRQLHINFMNNGKATPLHLAVQNGDLEMIKM 257
Score = 44.4 bits (100), Expect = 0.001
Identities = 41/164 (25%), Positives = 64/164 (39%), Gaps = 7/164 (4%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
G TPL A P + L+ + +++D + +H A + + LL+ +
Sbjct: 413 GCTPLHYACRQGGPGSVN-NLLGFNVSIHSKSKDKKSPLHFAASYGRINTCQRLLQDISD 471
Query: 168 P---NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQH 224
N D G+TPL+L+ N D ++ LL + +D GW +H A G Q
Sbjct: 472 TRLLNEGDLHGMTPLHLAAKNGHDKVV--QLLLKKGALFLSDHNGWTALHHASMGGYTQT 529
Query: 225 VDHLLFYGADMNAR-NASGNTPLHVCAVNAQDSCARQLLFRGCD 267
+ +L R + GNT LH A LL D
Sbjct: 530 MKVILDTNLKCTDRLDEDGNTALHFAAREGHAKAVALLLSHNAD 573
Score = 41.9 bits (94), Expect = 0.005
Identities = 42/174 (24%), Positives = 74/174 (42%), Gaps = 7/174 (4%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNK- 186
L++ GA ++ +G + + A S V LL GA + KD G L+L+V
Sbjct: 328 LISVGADINKIDSEGRSPLILATASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPY 387
Query: 187 -TDPLLCETLLHDHAT--IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGN 243
L E + + D G +H ACR G V++LL + +++++
Sbjct: 388 GLKNLRPEFMQMQQIKELVMDEDNDGCTPLHYACRQGGPGSVNNLLGFNVSIHSKSKDKK 447
Query: 244 TPLHVCAVNAQDSCARQLLFRGCDKEALN---FANQTPYQVAVIAGNLDLAEVI 294
+PLH A + + ++LL D LN TP +A G+ + +++
Sbjct: 448 SPLHFAASYGRINTCQRLLQDISDTRLLNEGDLHGMTPLHLAAKNGHDKVVQLL 501
Score = 41.1 bits (92), Expect = 0.009
Identities = 41/181 (22%), Positives = 79/181 (43%), Gaps = 17/181 (9%)
Query: 135 LDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCET 194
+++ +T +H AV+ LE +K L+ GA + + T ++ + T ++ +
Sbjct: 232 INFMNNGKATPLHLAVQNGDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIV-KL 290
Query: 195 LLHDHATIGATDLQGWQE-VHQAC--RNGLVQH---VDHLLFYGADMNARNASGNTPLHV 248
++ ++ G+ D+ + H+ R L H D+L+ GAD+N ++ G +PL +
Sbjct: 291 MISSYS--GSVDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLIL 348
Query: 249 CAVNAQDSCARQLLFRGC-----DKEALNFAN---QTPYQVAVIAGNLDLAEVIKNYKSD 300
+A + LL +G D NF + Q PY + + + IK D
Sbjct: 349 ATASASWNIVNLLLSKGAQVDIKDNFGRNFLHLTVQQPYGLKNLRPEFMQMQQIKELVMD 408
Query: 301 E 301
E
Sbjct: 409 E 409
Score = 36.7 bits (81), Expect = 0.20
Identities = 18/61 (29%), Positives = 30/61 (49%)
Query: 242 GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSDE 301
GNTPLH Q + LL RG + NF P +AV N ++ +V+ +++ +
Sbjct: 98 GNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTID 157
Query: 302 I 302
+
Sbjct: 158 V 158
Score = 36.7 bits (81), Expect = 0.20
Identities = 56/251 (22%), Positives = 102/251 (40%), Gaps = 24/251 (9%)
Query: 64 KTLKALHSRANLRRF-----LEHVTHGQIDKITKACA--KGLDPNFHCQETGETPLTIAA 116
K L + + NLR F L G +++ K + +D N E G T + IA
Sbjct: 115 KFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHRTIDVNLE-GENGNTAVIIAC 173
Query: 117 GLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNY------ 170
+ + I L+N GA + G +H+A S E ++ +L G Y
Sbjct: 174 TTNNSEALQI-LLNKGAKPCKSNKWGCFPIHQAAFSGSKECMEIILRFGEEHGYSRQLHI 232
Query: 171 ---KDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
+GK TPL+L+V N D + + L + A I + +H A G + V
Sbjct: 233 NFMNNGKA-TPLHLAVQN-GDLEMIKMCLDNGAQIDPVEKGRCTAIHFAATQGATEIVKL 290
Query: 228 LL--FYGA--DMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
++ + G+ +N + T LH ++ A L+ G D ++ ++P +A
Sbjct: 291 MISSYSGSVDIVNTTDGCHETMLHRASLFDHHELADYLISVGADINKIDSEGRSPLILAT 350
Query: 284 IAGNLDLAEVI 294
+ + ++ ++
Sbjct: 351 ASASWNIVNLL 361
Score = 32.7 bits (71), Expect = 3.3
Identities = 29/120 (24%), Positives = 53/120 (44%), Gaps = 3/120 (2%)
Query: 63 EKTLKALHSRANLRRFLEH--VTHGQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKS 120
+ +L+ LH + H V QI+ + ++G +PN PL IA +
Sbjct: 85 DSSLEVLHEMDDYGNTPLHCAVEKNQIESVKFLLSRGANPNLR-NFNMMAPLHIAVQGMN 143
Query: 121 PAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLY 180
+ + L + ++ +G+TA+ A N+ EA++ LL GA P + G P++
Sbjct: 144 NEVMKVLLEHRTIDVNLEGENGNTAVIIACTTNNSEALQILLNKGAKPCKSNKWGCFPIH 203
Score = 31.5 bits (68), Expect = 7.5
Identities = 23/92 (25%), Positives = 36/92 (39%), Gaps = 1/92 (1%)
Query: 206 DLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL-FR 264
D G +H A ++ V LL GA+ N RN + PLH+ + + LL R
Sbjct: 95 DDYGNTPLHCAVEKNQIESVKFLLSRGANPNLRNFNMMAPLHIAVQGMNNEVMKVLLEHR 154
Query: 265 GCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
D T +A N + +++ N
Sbjct: 155 TIDVNLEGENGNTAVIIACTTNNSEALQILLN 186
>BC052988-1|AAH52988.1| 980|Homo sapiens retinoic acid induced 14
protein.
Length = 980
Score = 64.5 bits (150), Expect = 9e-10
Identities = 52/193 (26%), Positives = 85/193 (44%), Gaps = 6/193 (3%)
Query: 77 RFLEHVTHGQIDKITKACAK-GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALL 135
R L+ V +G +K+ K G H E G+T +AA K + L ++ G +
Sbjct: 22 RLLQAVENGDAEKVASLLGKKGASATKHDSE-GKTAFHLAAA-KGHVECLRVMITHGVDV 79
Query: 136 DYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETL 195
+ G +A+H A + + E ++ LL+ D G T L+ + L +
Sbjct: 80 TAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGC--LQAVQI 137
Query: 196 LHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
L +H + I DL G + A +NG + LL +GAD+N+RN SG T L +
Sbjct: 138 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGS 197
Query: 255 DSCARQLLFRGCD 267
+ L+ +G D
Sbjct: 198 SNAVEALIKKGAD 210
Score = 62.9 bits (146), Expect = 3e-09
Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 1/172 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
K+ L GA +G TA H A K +E ++ ++ G +D G + L+L+
Sbjct: 34 KVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLA 93
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
N + LL + D G +H A G +Q V L + + +N ++ G
Sbjct: 94 AKNSHHECI-RKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDG 152
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
N PL + N LL G D + N + +T +A G+ + E +
Sbjct: 153 NIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEAL 204
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 3/163 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ + G+D TG + L +AA S + + L+ + G T
Sbjct: 64 GHVECLRVMITHGVDVTAQ-DTTGHSALHLAAK-NSHHECIRKLLQSKCPAESVDSSGKT 121
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A + L+AV+ L E + N KD G PL L+V N + C LL A + +
Sbjct: 122 ALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEI-CHFLLDHGADVNS 180
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ G + AC G V+ L+ GAD+N ++ G LH
Sbjct: 181 RNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALH 223
Score = 54.4 bits (125), Expect = 9e-07
Identities = 26/94 (27%), Positives = 50/94 (53%)
Query: 206 DLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRG 265
D +G H A G V+ + ++ +G D+ A++ +G++ LH+ A N+ C R+LL
Sbjct: 50 DSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSK 109
Query: 266 CDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
C E+++ + +T A G L +++ +KS
Sbjct: 110 CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKS 143
>AY354204-1|AAQ63889.2| 972|Homo sapiens retinoic acid induced 14
isoform protein.
Length = 972
Score = 64.5 bits (150), Expect = 9e-10
Identities = 52/193 (26%), Positives = 85/193 (44%), Gaps = 6/193 (3%)
Query: 77 RFLEHVTHGQIDKITKACAK-GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALL 135
R L+ V +G +K+ K G H E G+T +AA K + L ++ G +
Sbjct: 14 RLLQAVENGDAEKVASLLGKKGASATKHDSE-GKTAFHLAAA-KGHVECLRVMITHGVDV 71
Query: 136 DYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETL 195
+ G +A+H A + + E ++ LL+ D G T L+ + L +
Sbjct: 72 TAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGC--LQAVQI 129
Query: 196 LHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
L +H + I DL G + A +NG + LL +GAD+N+RN SG T L +
Sbjct: 130 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGS 189
Query: 255 DSCARQLLFRGCD 267
+ L+ +G D
Sbjct: 190 SNAVEALIKKGAD 202
Score = 62.9 bits (146), Expect = 3e-09
Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 1/172 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
K+ L GA +G TA H A K +E ++ ++ G +D G + L+L+
Sbjct: 26 KVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLA 85
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
N + LL + D G +H A G +Q V L + + +N ++ G
Sbjct: 86 AKNSHHECI-RKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDG 144
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
N PL + N LL G D + N + +T +A G+ + E +
Sbjct: 145 NIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEAL 196
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 3/163 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ + G+D TG + L +AA S + + L+ + G T
Sbjct: 56 GHVECLRVMITHGVDVTAQ-DTTGHSALHLAAK-NSHHECIRKLLQSKCPAESVDSSGKT 113
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A + L+AV+ L E + N KD G PL L+V N + C LL A + +
Sbjct: 114 ALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEI-CHFLLDHGADVNS 172
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ G + AC G V+ L+ GAD+N ++ G LH
Sbjct: 173 RNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALH 215
Score = 54.4 bits (125), Expect = 9e-07
Identities = 26/94 (27%), Positives = 50/94 (53%)
Query: 206 DLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRG 265
D +G H A G V+ + ++ +G D+ A++ +G++ LH+ A N+ C R+LL
Sbjct: 42 DSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSK 101
Query: 266 CDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
C E+++ + +T A G L +++ +KS
Sbjct: 102 CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKS 135
>AK001283-1|BAA91599.1| 445|Homo sapiens protein ( Homo sapiens
cDNA FLJ10421 fis, clone NT2RP1000202, weakly similar to
ANKYRIN. ).
Length = 445
Score = 64.5 bits (150), Expect = 9e-10
Identities = 45/163 (27%), Positives = 72/163 (44%)
Query: 138 RTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLH 197
+T +G A+H A + + V+ LLE GA PN + TPL+ +V N +L L H
Sbjct: 2 KTFEGFCALHLAASQGHWKIVQILLEAGADPNATTLEETTPLFSAVENGQIDVLRLLLQH 61
Query: 198 DHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSC 257
G+ + GW +HQA + + LL GA+ ++ G TPL V A +
Sbjct: 62 GANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKECQDDFGITPLFVAAQYGKLES 121
Query: 258 ARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
L+ G + TP +A G+ E++ + +D
Sbjct: 122 LSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLSSGAD 164
Score = 49.6 bits (113), Expect = 3e-05
Identities = 54/204 (26%), Positives = 85/204 (41%), Gaps = 12/204 (5%)
Query: 97 GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLE 156
G DPN E TPL A + + L +G + + G ++H+A + + E
Sbjct: 29 GADPNATTLEE-TTPLFSAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAE 87
Query: 157 AVKTLLELGASPNYKDGKGLTPLYLSVT-NKTDPLLCETLLHDHATIGATDLQGWQEVHQ 215
+K LL GA+ +D G+TPL+++ K + L L+ A + L +
Sbjct: 88 IIKLLLRKGANKECQDDFGITPLFVAAQYGKLESL--SILISSGANVNCQALDKATPLFI 145
Query: 216 ACRNGLVQHVDHLLFYGA--DMNARNASGNTPLHVCAVNAQDSCARQLL---FRGCDKEA 270
A + G + V+ LL GA D+ S P+H A L+ R CD
Sbjct: 146 AAQEGHTKCVELLLSSGADPDLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRACD-TG 204
Query: 271 LNFANQTPYQVAVIAGNLDLAEVI 294
LN +P AV G+ D E++
Sbjct: 205 LN--KVSPVYSAVFGGHEDCLEIL 226
Score = 49.2 bits (112), Expect = 4e-05
Identities = 40/164 (24%), Positives = 74/164 (45%), Gaps = 4/164 (2%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGK-GLTPLYL 181
KI+ L+ GA + T + +T + AVE ++ ++ LL+ GA+ N G L+
Sbjct: 20 KIVQILLEAGADPNATTLEETTPLFSAVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQ 79
Query: 182 SVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNAS 241
+ + ++ + LL A D G + A + G ++ + L+ GA++N +
Sbjct: 80 ASFQENAEII-KLLLRKGANKECQDDFGITPLFVAAQYGKLESLSILISSGANVNCQALD 138
Query: 242 GNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIA 285
TPL + A C LL G D + + N+ +Q+ + A
Sbjct: 139 KATPLFIAAQEGHTKCVELLLSSGADPDL--YCNEDSWQLPIHA 180
>AF155135-1|AAF44722.1| 980|Homo sapiens novel retinal pigment
epithelial cell protein protein.
Length = 980
Score = 64.5 bits (150), Expect = 9e-10
Identities = 52/193 (26%), Positives = 85/193 (44%), Gaps = 6/193 (3%)
Query: 77 RFLEHVTHGQIDKITKACAK-GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALL 135
R L+ V +G +K+ K G H E G+T +AA K + L ++ G +
Sbjct: 22 RLLQAVENGDAEKVASLLGKKGASATKHDSE-GKTAFHLAAA-KGHVECLRVMITHGVDV 79
Query: 136 DYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETL 195
+ G +A+H A + + E ++ LL+ D G T L+ + L +
Sbjct: 80 TAQDTTGHSALHLAAKNSHHECIRRLLQSKCPAESVDSSGKTALHYAAAQGC--LQAVQI 137
Query: 196 LHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
L +H + I DL G + A +NG + LL +GAD+N+RN SG T L +
Sbjct: 138 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGS 197
Query: 255 DSCARQLLFRGCD 267
+ L+ +G D
Sbjct: 198 SNAVEALIKKGAD 210
Score = 62.9 bits (146), Expect = 3e-09
Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 1/172 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
K+ L GA +G TA H A K +E ++ ++ G +D G + L+L+
Sbjct: 34 KVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLA 93
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
N + LL + D G +H A G +Q V L + + +N ++ G
Sbjct: 94 AKNSHHECI-RRLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDG 152
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
N PL + N LL G D + N + +T +A G+ + E +
Sbjct: 153 NIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEAL 204
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 3/163 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ + G+D TG + L +AA S + + L+ + G T
Sbjct: 64 GHVECLRVMITHGVDVTAQ-DTTGHSALHLAAK-NSHHECIRRLLQSKCPAESVDSSGKT 121
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A + L+AV+ L E + N KD G PL L+V N + C LL A + +
Sbjct: 122 ALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEI-CHFLLDHGADVNS 180
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ G + AC G V+ L+ GAD+N ++ G LH
Sbjct: 181 RNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALH 223
Score = 54.4 bits (125), Expect = 9e-07
Identities = 26/94 (27%), Positives = 50/94 (53%)
Query: 206 DLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRG 265
D +G H A G V+ + ++ +G D+ A++ +G++ LH+ A N+ C R+LL
Sbjct: 50 DSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRRLLQSK 109
Query: 266 CDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
C E+++ + +T A G L +++ +KS
Sbjct: 110 CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKS 143
>AB037755-1|BAA92572.1| 989|Homo sapiens KIAA1334 protein protein.
Length = 989
Score = 64.5 bits (150), Expect = 9e-10
Identities = 52/193 (26%), Positives = 85/193 (44%), Gaps = 6/193 (3%)
Query: 77 RFLEHVTHGQIDKITKACAK-GLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALL 135
R L+ V +G +K+ K G H E G+T +AA K + L ++ G +
Sbjct: 31 RLLQAVENGDAEKVASLLGKKGASATKHDSE-GKTAFHLAAA-KGHVECLRVMITHGVDV 88
Query: 136 DYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETL 195
+ G +A+H A + + E ++ LL+ D G T L+ + L +
Sbjct: 89 TAQDTTGHSALHLAAKNSHHECIRKLLQSKCPAESVDSSGKTALHYAAAQGC--LQAVQI 146
Query: 196 LHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQ 254
L +H + I DL G + A +NG + LL +GAD+N+RN SG T L +
Sbjct: 147 LCEHKSPINLKDLDGNIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGS 206
Query: 255 DSCARQLLFRGCD 267
+ L+ +G D
Sbjct: 207 SNAVEALIKKGAD 219
Score = 62.9 bits (146), Expect = 3e-09
Identities = 42/172 (24%), Positives = 70/172 (40%), Gaps = 1/172 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
K+ L GA +G TA H A K +E ++ ++ G +D G + L+L+
Sbjct: 43 KVASLLGKKGASATKHDSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLA 102
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
N + LL + D G +H A G +Q V L + + +N ++ G
Sbjct: 103 AKNSHHECI-RKLLQSKCPAESVDSSGKTALHYAAAQGCLQAVQILCEHKSPINLKDLDG 161
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
N PL + N LL G D + N + +T +A G+ + E +
Sbjct: 162 NIPLLLAVQNGHSEICHFLLDHGADVNSRNKSGRTALMLACEIGSSNAVEAL 213
Score = 56.4 bits (130), Expect = 2e-07
Identities = 46/163 (28%), Positives = 72/163 (44%), Gaps = 3/163 (1%)
Query: 85 GQIDKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGST 144
G ++ + G+D TG + L +AA S + + L+ + G T
Sbjct: 73 GHVECLRVMITHGVDVTAQ-DTTGHSALHLAAK-NSHHECIRKLLQSKCPAESVDSSGKT 130
Query: 145 AMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGA 204
A+H A + L+AV+ L E + N KD G PL L+V N + C LL A + +
Sbjct: 131 ALHYAAAQGCLQAVQILCEHKSPINLKDLDGNIPLLLAVQNGHSEI-CHFLLDHGADVNS 189
Query: 205 TDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ G + AC G V+ L+ GAD+N ++ G LH
Sbjct: 190 RNKSGRTALMLACEIGSSNAVEALIKKGADLNLVDSLGYNALH 232
Score = 54.4 bits (125), Expect = 9e-07
Identities = 26/94 (27%), Positives = 50/94 (53%)
Query: 206 DLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRG 265
D +G H A G V+ + ++ +G D+ A++ +G++ LH+ A N+ C R+LL
Sbjct: 59 DSEGKTAFHLAAAKGHVECLRVMITHGVDVTAQDTTGHSALHLAAKNSHHECIRKLLQSK 118
Query: 266 CDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
C E+++ + +T A G L +++ +KS
Sbjct: 119 CPAESVDSSGKTALHYAAAQGCLQAVQILCEHKS 152
>CR457336-1|CAG33617.1| 288|Homo sapiens ASB8 protein.
Length = 288
Score = 64.1 bits (149), Expect = 1e-09
Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 3/143 (2%)
Query: 158 VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQAC 217
V+ L+ GA N G L PL+ + +D E LL A + A D +H A
Sbjct: 37 VEDLIRGGADVNCTHGT-LKPLHCACM-VSDADCVELLLEKGAEVNALDGYNRTALHYAA 94
Query: 218 RNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQT 277
V+ LL YGA+ NA + + +TPLH A C R LL G AL++ N T
Sbjct: 95 EKDEAC-VEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDT 153
Query: 278 PYQVAVIAGNLDLAEVIKNYKSD 300
P A + GNL+ ++ +Y ++
Sbjct: 154 PLSWAAMKGNLESVSILLDYGAE 176
Score = 61.7 bits (143), Expect = 6e-09
Identities = 50/159 (31%), Positives = 71/159 (44%), Gaps = 5/159 (3%)
Query: 88 DKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMH 147
D + G D N C PL A + S A + L+ GA ++ TA+H
Sbjct: 35 DNVEDLIRGGADVN--CTHGTLKPLHCAC-MVSDADCVELLLEKGAEVNALDGYNRTALH 91
Query: 148 RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDL 207
A EK+ V+ LLE GA+PN DG TPL+ + K + LL A++ A D
Sbjct: 92 YAAEKDEA-CVEVLLEYGANPNALDGNRDTPLHWAAF-KNNAECVRALLESGASVNALDY 149
Query: 208 QGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPL 246
+ A G ++ V LL YGA++ N G TP+
Sbjct: 150 NNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPI 188
Score = 54.8 bits (126), Expect = 7e-07
Identities = 50/166 (30%), Positives = 70/166 (42%), Gaps = 3/166 (1%)
Query: 113 TIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKD 172
TIAA P + L+ GGA ++ T +H A + + V+ LLE GA N D
Sbjct: 25 TIAAIRSFPHDNVEDLIRGGADVNC-THGTLKPLHCACMVSDADCVELLLEKGAEVNALD 83
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
G T L+ + + D E LL A A D +H A + V LL G
Sbjct: 84 GYNRTALHYAA--EKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESG 141
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
A +NA + + +TPL A+ LL G + +N QTP
Sbjct: 142 ASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTP 187
>BC001321-1|AAH01321.1| 288|Homo sapiens ankyrin repeat and SOCS
box-containing 8 protein.
Length = 288
Score = 64.1 bits (149), Expect = 1e-09
Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 3/143 (2%)
Query: 158 VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQAC 217
V+ L+ GA N G L PL+ + +D E LL A + A D +H A
Sbjct: 37 VEDLIRGGADVNCTHGT-LKPLHCACM-VSDADCVELLLEKGAEVNALDGYNRTALHYAA 94
Query: 218 RNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQT 277
V+ LL YGA+ NA + + +TPLH A C R LL G AL++ N T
Sbjct: 95 EKDEAC-VEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDT 153
Query: 278 PYQVAVIAGNLDLAEVIKNYKSD 300
P A + GNL+ ++ +Y ++
Sbjct: 154 PLSWAAMKGNLESVSILLDYGAE 176
Score = 61.7 bits (143), Expect = 6e-09
Identities = 50/159 (31%), Positives = 71/159 (44%), Gaps = 5/159 (3%)
Query: 88 DKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMH 147
D + G D N C PL A + S A + L+ GA ++ TA+H
Sbjct: 35 DNVEDLIRGGADVN--CTHGTLKPLHCAC-MVSDADCVELLLEKGAEVNALDGYNRTALH 91
Query: 148 RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDL 207
A EK+ V+ LLE GA+PN DG TPL+ + K + LL A++ A D
Sbjct: 92 YAAEKDEA-CVEVLLEYGANPNALDGNRDTPLHWAAF-KNNAECVRALLESGASVNALDY 149
Query: 208 QGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPL 246
+ A G ++ V LL YGA++ N G TP+
Sbjct: 150 NNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPI 188
Score = 54.8 bits (126), Expect = 7e-07
Identities = 50/166 (30%), Positives = 70/166 (42%), Gaps = 3/166 (1%)
Query: 113 TIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKD 172
TIAA P + L+ GGA ++ T +H A + + V+ LLE GA N D
Sbjct: 25 TIAAIRSFPHDNVEDLIRGGADVNC-THGTLKPLHCACMVSDADCVELLLEKGAEVNALD 83
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
G T L+ + + D E LL A A D +H A + V LL G
Sbjct: 84 GYNRTALHYAA--EKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESG 141
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
A +NA + + +TPL A+ LL G + +N QTP
Sbjct: 142 ASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTP 187
>AK024908-1|BAB15033.1| 288|Homo sapiens NP3) mRNA. protein.
Length = 288
Score = 64.1 bits (149), Expect = 1e-09
Identities = 46/143 (32%), Positives = 67/143 (46%), Gaps = 3/143 (2%)
Query: 158 VKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQAC 217
V+ L+ GA N G L PL+ + +D E LL A + A D +H A
Sbjct: 37 VEDLIRGGADVNCTHGT-LKPLHCACM-VSDADCVELLLEKGAEVNALDGYNRTALHYAA 94
Query: 218 RNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQT 277
V+ LL YGA+ NA + + +TPLH A C R LL G AL++ N T
Sbjct: 95 EKDEAC-VEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESGASVNALDYNNDT 153
Query: 278 PYQVAVIAGNLDLAEVIKNYKSD 300
P A + GNL+ ++ +Y ++
Sbjct: 154 PLSWAAMKGNLESVSILLDYGAE 176
Score = 61.7 bits (143), Expect = 6e-09
Identities = 50/159 (31%), Positives = 71/159 (44%), Gaps = 5/159 (3%)
Query: 88 DKITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMH 147
D + G D N C PL A + S A + L+ GA ++ TA+H
Sbjct: 35 DNVEDLIRGGADVN--CTHGTLKPLHCAC-MVSDADCVELLLEKGAEVNALDGYNRTALH 91
Query: 148 RAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDL 207
A EK+ V+ LLE GA+PN DG TPL+ + K + LL A++ A D
Sbjct: 92 YAAEKDEA-CVEVLLEYGANPNALDGNRDTPLHWAAF-KNNAECVRALLESGASVNALDY 149
Query: 208 QGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPL 246
+ A G ++ V LL YGA++ N G TP+
Sbjct: 150 NNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTPI 188
Score = 54.8 bits (126), Expect = 7e-07
Identities = 50/166 (30%), Positives = 70/166 (42%), Gaps = 3/166 (1%)
Query: 113 TIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKD 172
TIAA P + L+ GGA ++ T +H A + + V+ LLE GA N D
Sbjct: 25 TIAAIRSFPHDNVEDLIRGGADVNC-THGTLKPLHCACMVSDADCVELLLEKGAEVNALD 83
Query: 173 GKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYG 232
G T L+ + + D E LL A A D +H A + V LL G
Sbjct: 84 GYNRTALHYAA--EKDEACVEVLLEYGANPNALDGNRDTPLHWAAFKNNAECVRALLESG 141
Query: 233 ADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTP 278
A +NA + + +TPL A+ LL G + +N QTP
Sbjct: 142 ASVNALDYNNDTPLSWAAMKGNLESVSILLDYGAEVRVINLIGQTP 187
>D83197-1|BAA34594.1| 226|Homo sapiens gankyrin protein.
Length = 226
Score = 63.7 bits (148), Expect = 2e-09
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 1/160 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
+I+ L+ G ++ + G + +H A E VK LL GA N + G TPL+ +
Sbjct: 54 EIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYA 113
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
+ K + LL A A D +H+A G ++ + LL+Y A N ++ G
Sbjct: 114 AS-KNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
NTPLH+ + A+ L+ +G N +TP QVA
Sbjct: 173 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 3/96 (3%)
Query: 88 DKITKAC-AKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAM 146
D+I KA KG N + G TPL AA K+ +I + L+ GGA D + +TAM
Sbjct: 86 DEIVKALLGKGAQVNA-VNQNGCTPLHYAAS-KNRHEIAVMLLEGGANPDAKDHYEATAM 143
Query: 147 HRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
HRA K +L+ + LL AS N +D +G TPL+L+
Sbjct: 144 HRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/109 (32%), Positives = 49/109 (44%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ E LL + D GW +H A G + V LL GA +NA N +G TPLH A
Sbjct: 55 IVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAA 114
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
+ A LL G + +A + T A GNL + ++ YK+
Sbjct: 115 SKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
Score = 53.2 bits (122), Expect = 2e-06
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 1/155 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+D TA+H A E V+ LL+LG N KD G +PL+++ + D ++ + LL
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIV-KALLGKG 96
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + A + G +H A + LL GA+ +A++ T +H A
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL+ + TP +A ++ A+++
Sbjct: 157 ILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191
Score = 52.0 bits (119), Expect = 5e-06
Identities = 30/104 (28%), Positives = 50/104 (48%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
L E++L D + TD +H AC G + V+ LL G +N ++ +G +PLH+ A
Sbjct: 22 LKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAA 81
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+D + LL +G A+N TP A ++A ++
Sbjct: 82 SAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Score = 31.1 bits (67), Expect = 9.9
Identities = 18/67 (26%), Positives = 35/67 (52%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKG 175
A K K++ L+ A + + +G+T +H A ++ +E K L+ GAS ++ +
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
Query: 176 LTPLYLS 182
TPL ++
Sbjct: 206 KTPLQVA 212
>BC011960-1|AAH11960.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 63.7 bits (148), Expect = 2e-09
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 1/160 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
+I+ L+ G ++ + G + +H A E VK LL GA N + G TPL+ +
Sbjct: 54 EIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYA 113
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
+ K + LL A A D +H+A G ++ + LL+Y A N ++ G
Sbjct: 114 AS-KNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
NTPLH+ + A+ L+ +G N +TP QVA
Sbjct: 173 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 3/96 (3%)
Query: 88 DKITKAC-AKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAM 146
D+I KA KG N + G TPL AA K+ +I + L+ GGA D + +TAM
Sbjct: 86 DEIVKALLGKGAQVNA-VNQNGCTPLHYAAS-KNRHEIAVMLLEGGANPDAKDHYEATAM 143
Query: 147 HRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
HRA K +L+ + LL AS N +D +G TPL+L+
Sbjct: 144 HRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/109 (32%), Positives = 49/109 (44%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ E LL + D GW +H A G + V LL GA +NA N +G TPLH A
Sbjct: 55 IVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAA 114
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
+ A LL G + +A + T A GNL + ++ YK+
Sbjct: 115 SKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
Score = 53.2 bits (122), Expect = 2e-06
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 1/155 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+D TA+H A E V+ LL+LG N KD G +PL+++ + D ++ + LL
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIV-KALLGKG 96
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + A + G +H A + LL GA+ +A++ T +H A
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL+ + TP +A ++ A+++
Sbjct: 157 ILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191
Score = 52.0 bits (119), Expect = 5e-06
Identities = 30/104 (28%), Positives = 50/104 (48%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
L E++L D + TD +H AC G + V+ LL G +N ++ +G +PLH+ A
Sbjct: 22 LKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAA 81
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+D + LL +G A+N TP A ++A ++
Sbjct: 82 SAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Score = 31.1 bits (67), Expect = 9.9
Identities = 18/67 (26%), Positives = 35/67 (52%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKG 175
A K K++ L+ A + + +G+T +H A ++ +E K L+ GAS ++ +
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
Query: 176 LTPLYLS 182
TPL ++
Sbjct: 206 KTPLQVA 212
>AL031177-5|CAA20117.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 63.7 bits (148), Expect = 2e-09
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 1/160 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
+I+ L+ G ++ + G + +H A E VK LL GA N + G TPL+ +
Sbjct: 54 EIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYA 113
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
+ K + LL A A D +H+A G ++ + LL+Y A N ++ G
Sbjct: 114 AS-KNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
NTPLH+ + A+ L+ +G N +TP QVA
Sbjct: 173 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 3/96 (3%)
Query: 88 DKITKAC-AKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAM 146
D+I KA KG N + G TPL AA K+ +I + L+ GGA D + +TAM
Sbjct: 86 DEIVKALLGKGAQVNA-VNQNGCTPLHYAAS-KNRHEIAVMLLEGGANPDAKDHYEATAM 143
Query: 147 HRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
HRA K +L+ + LL AS N +D +G TPL+L+
Sbjct: 144 HRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/109 (32%), Positives = 49/109 (44%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ E LL + D GW +H A G + V LL GA +NA N +G TPLH A
Sbjct: 55 IVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAA 114
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
+ A LL G + +A + T A GNL + ++ YK+
Sbjct: 115 SKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
Score = 53.2 bits (122), Expect = 2e-06
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 1/155 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+D TA+H A E V+ LL+LG N KD G +PL+++ + D ++ + LL
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIV-KALLGKG 96
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + A + G +H A + LL GA+ +A++ T +H A
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL+ + TP +A ++ A+++
Sbjct: 157 ILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191
Score = 52.0 bits (119), Expect = 5e-06
Identities = 30/104 (28%), Positives = 50/104 (48%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
L E++L D + TD +H AC G + V+ LL G +N ++ +G +PLH+ A
Sbjct: 22 LKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAA 81
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+D + LL +G A+N TP A ++A ++
Sbjct: 82 SAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Score = 31.1 bits (67), Expect = 9.9
Identities = 18/67 (26%), Positives = 35/67 (52%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKG 175
A K K++ L+ A + + +G+T +H A ++ +E K L+ GAS ++ +
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
Query: 176 LTPLYLS 182
TPL ++
Sbjct: 206 KTPLQVA 212
>AB051515-1|BAB21819.1| 1644|Homo sapiens KIAA1728 protein protein.
Length = 1644
Score = 63.7 bits (148), Expect = 2e-09
Identities = 48/176 (27%), Positives = 78/176 (44%), Gaps = 2/176 (1%)
Query: 108 GETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGAS 167
GET LT AAG + ++ L+ GA + R G + A + + V+ LLE G
Sbjct: 862 GETALTAAAG-RGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCD 920
Query: 168 PNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDH 227
N D +G TPL ++ + E LL A + + D +G + AC G V +
Sbjct: 921 VNLSDKQGRTPLMVAACEGHLSTV-EFLLSKGAALSSLDKEGLSALSWACLKGHRAVVQY 979
Query: 228 LLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAV 283
L+ GA ++ + +G TPL + A L+ +G E ++ + P A+
Sbjct: 980 LVEEGAAIDQTDKNGRTPLDLAAFYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAI 1035
Score = 45.6 bits (103), Expect = 4e-04
Identities = 48/200 (24%), Positives = 76/200 (38%), Gaps = 12/200 (6%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
E G T L AA K++ L G +D+ + G A+ + + + ++ LL
Sbjct: 749 ENGMTALCYAAAA-GHMKLVCLLTKKGVRVDHLDKKGQCALVHSALRGHGDILQYLLTCE 807
Query: 166 ASPN------YKDGKGLTPLYLSVTNKTDPLLCETLL-----HDHATIGATDLQGWQEVH 214
SP + L + + + + LL H+ G L G +
Sbjct: 808 WSPGPPQPGTLRKSHALQQALTAAASMGHSSVVQCLLGMEKEHEVEVNGTDTLWGETALT 867
Query: 215 QACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFA 274
A G ++ + LL +GA ++ N G PL A R LL RGCD +
Sbjct: 868 AAAGRGKLEVCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQ 927
Query: 275 NQTPYQVAVIAGNLDLAEVI 294
+TP VA G+L E +
Sbjct: 928 GRTPLMVAACEGHLSTVEFL 947
Score = 42.7 bits (96), Expect = 0.003
Identities = 30/97 (30%), Positives = 43/97 (44%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+CE LL A + T+ +G + A R G Q V LL G D+N + G TPL V A
Sbjct: 877 VCELLLGHGAAVSRTNRRGVPPLFCAARQGHWQIVRLLLERGCDVNLSDKQGRTPLMVAA 936
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGN 287
S LL +G +L+ + A + G+
Sbjct: 937 CEGHLSTVEFLLSKGAALSSLDKEGLSALSWACLKGH 973
Score = 32.7 bits (71), Expect = 3.3
Identities = 19/61 (31%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Query: 106 ETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELG 165
+ G TPL +AA A+ ++ LV GA++++ G + RA+ + V LL G
Sbjct: 992 KNGRTPLDLAA-FYGDAETVLYLVEKGAVIEHVDHSGMRPLDRAIGCRNTSVVVALLRKG 1050
Query: 166 A 166
A
Sbjct: 1051 A 1051
>AB009619-1|BAA33215.1| 226|Homo sapiens 26S proteasome subunit p28
protein.
Length = 226
Score = 63.7 bits (148), Expect = 2e-09
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 1/160 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
+I+ L+ G ++ + G + +H A E VK LL GA N + G TPL+ +
Sbjct: 54 EIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYA 113
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
+ K + LL A A D +H+A G ++ + LL+Y A N ++ G
Sbjct: 114 AS-KNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
NTPLH+ + A+ L+ +G N +TP QVA
Sbjct: 173 NTPLHLACDEERVEEAKLLVSQGASIYIENKEEKTPLQVA 212
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 3/96 (3%)
Query: 88 DKITKAC-AKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAM 146
D+I KA KG N + G TPL AA K+ +I + L+ GGA D + +TAM
Sbjct: 86 DEIVKALLGKGAQVNA-VNQNGCTPLHYAAS-KNRHEIAVMLLEGGANPDAKDHYEATAM 143
Query: 147 HRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
HRA K +L+ + LL AS N +D +G TPL+L+
Sbjct: 144 HRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/109 (32%), Positives = 49/109 (44%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ E LL + D GW +H A G + V LL GA +NA N +G TPLH A
Sbjct: 55 IVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAA 114
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
+ A LL G + +A + T A GNL + ++ YK+
Sbjct: 115 SKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
Score = 53.2 bits (122), Expect = 2e-06
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 1/155 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+D TA+H A E V+ LL+LG N KD G +PL+++ + D ++ + LL
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIV-KALLGKG 96
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + A + G +H A + LL GA+ +A++ T +H A
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL+ + TP +A ++ A+++
Sbjct: 157 ILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191
Score = 52.0 bits (119), Expect = 5e-06
Identities = 30/104 (28%), Positives = 50/104 (48%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
L E++L D + TD +H AC G + V+ LL G +N ++ +G +PLH+ A
Sbjct: 22 LKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAA 81
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+D + LL +G A+N TP A ++A ++
Sbjct: 82 SAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
Score = 31.1 bits (67), Expect = 9.9
Identities = 18/67 (26%), Positives = 35/67 (52%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKG 175
A K K++ L+ A + + +G+T +H A ++ +E K L+ GAS ++ +
Sbjct: 146 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 205
Query: 176 LTPLYLS 182
TPL ++
Sbjct: 206 KTPLQVA 212
>BT019689-1|AAV38495.1| 226|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 226
Score = 63.3 bits (147), Expect = 2e-09
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 1/160 (0%)
Query: 123 KILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
+I+ L+ G ++ + G + +H A E VK LL GA N + G TPL+ +
Sbjct: 54 EIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYA 113
Query: 183 VTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASG 242
+ K + LL A A D +H+A G ++ + LL+Y A N ++ G
Sbjct: 114 AS-KNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEG 172
Query: 243 NTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVA 282
NTPLH+ + A+ L+ +G N +TP QVA
Sbjct: 173 NTPLHLACDEERVEEAKLLVSQGTSIYIENKEEKTPLQVA 212
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 3/96 (3%)
Query: 88 DKITKAC-AKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAM 146
D+I KA KG N + G TPL AA K+ +I + L+ GGA D + +TAM
Sbjct: 86 DEIVKALLGKGAQVNA-VNQNGCTPLHYAAS-KNRHEIAVMLLEGGANPDAKDHYEATAM 143
Query: 147 HRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
HRA K +L+ + LL AS N +D +G TPL+L+
Sbjct: 144 HRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 179
Score = 54.4 bits (125), Expect = 9e-07
Identities = 35/109 (32%), Positives = 49/109 (44%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
+ E LL + D GW +H A G + V LL GA +NA N +G TPLH A
Sbjct: 55 IVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAA 114
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
+ A LL G + +A + T A GNL + ++ YK+
Sbjct: 115 SKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 163
Score = 53.2 bits (122), Expect = 2e-06
Identities = 39/155 (25%), Positives = 68/155 (43%), Gaps = 1/155 (0%)
Query: 140 RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDH 199
+D TA+H A E V+ LL+LG N KD G +PL+++ + D ++ + LL
Sbjct: 38 QDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAASAGRDEIV-KALLGKG 96
Query: 200 ATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCAR 259
A + A + G +H A + LL GA+ +A++ T +H A
Sbjct: 97 AQVNAVNQNGCTPLHYAASKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIH 156
Query: 260 QLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
LL+ + TP +A ++ A+++
Sbjct: 157 ILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 191
Score = 52.0 bits (119), Expect = 5e-06
Identities = 30/104 (28%), Positives = 50/104 (48%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
L E++L D + TD +H AC G + V+ LL G +N ++ +G +PLH+ A
Sbjct: 22 LKESILADKSLATRTDQDSRTALHWACSAGHTEIVEFLLQLGVPVNDKDDAGWSPLHIAA 81
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
+D + LL +G A+N TP A ++A ++
Sbjct: 82 SAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVML 125
>AL031177-4|CAI43134.1| 193|Homo sapiens proteasome (prosome,
macropain) 26S subunit, non-ATPase, 10 protein.
Length = 193
Score = 63.3 bits (147), Expect = 2e-09
Identities = 44/141 (31%), Positives = 65/141 (46%), Gaps = 1/141 (0%)
Query: 142 GSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHAT 201
G + +H A E VK LL GA N + G TPL+ + + K + LL A
Sbjct: 40 GWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAAS-KNRHEIAVMLLEGGAN 98
Query: 202 IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQL 261
A D +H+A G ++ + LL+Y A N ++ GNTPLH+ + A+ L
Sbjct: 99 PDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLL 158
Query: 262 LFRGCDKEALNFANQTPYQVA 282
+ +G N +TP QVA
Sbjct: 159 VSQGASIYIENKEEKTPLQVA 179
Score = 60.1 bits (139), Expect = 2e-08
Identities = 37/109 (33%), Positives = 52/109 (47%)
Query: 191 LCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCA 250
L E++L D + TD GW +H A G + V LL GA +NA N +G TPLH A
Sbjct: 22 LKESILADKSLATRTDQAGWSPLHIAASAGRDEIVKALLGKGAQVNAVNQNGCTPLHYAA 81
Query: 251 VNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNYKS 299
+ A LL G + +A + T A GNL + ++ YK+
Sbjct: 82 SKNRHEIAVMLLEGGANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKA 130
Score = 58.0 bits (134), Expect = 8e-08
Identities = 39/96 (40%), Positives = 54/96 (56%), Gaps = 3/96 (3%)
Query: 88 DKITKAC-AKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAM 146
D+I KA KG N + G TPL AA K+ +I + L+ GGA D + +TAM
Sbjct: 53 DEIVKALLGKGAQVNA-VNQNGCTPLHYAAS-KNRHEIAVMLLEGGANPDAKDHYEATAM 110
Query: 147 HRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLS 182
HRA K +L+ + LL AS N +D +G TPL+L+
Sbjct: 111 HRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLA 146
Score = 31.1 bits (67), Expect = 9.9
Identities = 26/123 (21%), Positives = 51/123 (41%), Gaps = 1/123 (0%)
Query: 172 DGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFY 231
D G +PL+++ + D ++ + LL A + A + G +H A + LL
Sbjct: 37 DQAGWSPLHIAASAGRDEIV-KALLGKGAQVNAVNQNGCTPLHYAASKNRHEIAVMLLEG 95
Query: 232 GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLA 291
GA+ +A++ T +H A LL+ + TP +A ++ A
Sbjct: 96 GANPDAKDHYEATAMHRAAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEA 155
Query: 292 EVI 294
+++
Sbjct: 156 KLL 158
Score = 31.1 bits (67), Expect = 9.9
Identities = 18/67 (26%), Positives = 35/67 (52%)
Query: 116 AGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKG 175
A K K++ L+ A + + +G+T +H A ++ +E K L+ GAS ++ +
Sbjct: 113 AAAKGNLKMIHILLYYKASTNIQDTEGNTPLHLACDEERVEEAKLLVSQGASIYIENKEE 172
Query: 176 LTPLYLS 182
TPL ++
Sbjct: 173 KTPLQVA 179
>DQ388145-2|ABD72216.1| 1482|Homo sapiens CTTNBP2 protein.
Length = 1482
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388144-2|ABD72214.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388143-2|ABD72212.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388142-2|ABD72210.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388141-2|ABD72208.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388140-2|ABD72206.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388139-2|ABD72204.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388138-2|ABD72202.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388137-2|ABD72200.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388136-2|ABD72198.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388135-2|ABD72196.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388134-2|ABD72194.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388133-2|ABD72192.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388132-2|ABD72190.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388131-2|ABD72188.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388130-2|ABD72186.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388129-2|ABD72184.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ388128-2|ABD72182.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ356264-2|ABC87066.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ356263-2|ABC87064.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ356262-2|ABC87062.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ356261-2|ABC87060.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ356260-2|ABC87058.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ356259-2|ABC87056.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ356258-2|ABC87054.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ356257-2|ABC87052.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ354391-2|ABC79055.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ354390-2|ABC79053.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ354389-2|ABC79051.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>DQ354388-2|ABC79049.1| 1663|Homo sapiens CTTNBP2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>CR457302-1|CAG33583.1| 278|Homo sapiens ASB13 protein.
Length = 278
Score = 62.9 bits (146), Expect = 3e-09
Identities = 46/167 (27%), Positives = 75/167 (44%), Gaps = 3/167 (1%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA ++ T D T +H A + V+ LL GA + ++ G TPL + + +
Sbjct: 38 LIESGACVNQVTVDSITPLHAASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGS 97
Query: 188 DPLLCETLLHDHATIGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLH 247
+ C LL + L +H+AC +G + V L+ GA++ A + TPLH
Sbjct: 98 --IECVKLLLSYGAKVNPPLYTASPLHEACMSGSSECVRLLIDVGANLEAHDCHFGTPLH 155
Query: 248 VCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVI 294
V C + LL G + A ++T A N+DL E++
Sbjct: 156 VACAREHLDCVKVLLNAGANVNAAKL-HETALHHAAKVKNVDLIEML 201
Score = 62.5 bits (145), Expect = 4e-09
Identities = 43/153 (28%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Query: 144 TAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIG 203
T +H A ++ ++ L+E GA N +TPL+ + + + + LL A +
Sbjct: 21 TPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLH-AASLQGQARCVQLLLAAGAQVD 79
Query: 204 ATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLF 263
A ++ G + AC +G ++ V LL YGA +N + + PLH ++ C R L+
Sbjct: 80 ARNIDGSTPLCDACASGSIECVKLLLSYGAKVNPPLYTAS-PLHEACMSGSSECVRLLID 138
Query: 264 RGCDKEALNFANQTPYQVAVIAGNLDLAEVIKN 296
G + EA + TP VA +LD +V+ N
Sbjct: 139 VGANLEAHDCHFGTPLHVACAREHLDCVKVLLN 171
Score = 51.2 bits (117), Expect = 9e-06
Identities = 50/157 (31%), Positives = 68/157 (43%), Gaps = 5/157 (3%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL AA L+ A+ + L+ GA +D R DGST + A S+E VK LL GA N
Sbjct: 54 TPLH-AASLQGQARCVQLLLAAGAQVDARNIDGSTPLCDACASGSIECVKLLLSYGAKVN 112
Query: 170 YKDGKGLTPLYLSVTNKTDPLLCETLLHD-HATIGATDLQGWQEVHQACRNGLVQHVDHL 228
+PL+ + + + C LL D A + A D +H AC + V L
Sbjct: 113 -PPLYTASPLHEACMSGSSE--CVRLLIDVGANLEAHDCHFGTPLHVACAREHLDCVKVL 169
Query: 229 LFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRG 265
L GA++NA H V D + F G
Sbjct: 170 LNAGANVNAAKLHETALHHAAKVKNVDLIEMLIEFGG 206
Score = 48.0 bits (109), Expect = 8e-05
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 3/95 (3%)
Query: 206 DLQGWQE---VHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLL 262
D+ W E VH+A + G + L+ GA +N TPLH ++ Q C + LL
Sbjct: 13 DVGFWVERTPVHEAAQRGESLQLQQLIESGACVNQVTVDSITPLHAASLQGQARCVQLLL 72
Query: 263 FRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
G +A N TP A +G+++ +++ +Y
Sbjct: 73 AAGAQVDARNIDGSTPLCDACASGSIECVKLLLSY 107
Score = 31.5 bits (68), Expect = 7.5
Identities = 18/69 (26%), Positives = 36/69 (52%), Gaps = 2/69 (2%)
Query: 110 TPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPN 169
TPL +A + + L+N GA ++ + TA+H A + +++ ++ L+E G +
Sbjct: 152 TPLHVACA-REHLDCVKVLLNAGANVN-AAKLHETALHHAAKVKNVDLIEMLIEFGGNIY 209
Query: 170 YKDGKGLTP 178
+D +G P
Sbjct: 210 ARDNRGKKP 218
>BC118585-1|AAI18586.1| 273|Homo sapiens ASB16 protein protein.
Length = 273
Score = 62.9 bits (146), Expect = 3e-09
Identities = 45/136 (33%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA LD R G A+H A + + V+ LL GA N +G TPL+L ++
Sbjct: 130 LIRQGAELDARV-GGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPES 188
Query: 188 DPLLC-ETLLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
L C + LL AT+ + + +H A GL QHV L +GAD+ R + G T
Sbjct: 189 --LQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETA 246
Query: 246 LHVCAVNAQDSCARQL 261
L+ A+ A L
Sbjct: 247 LNTACAGAEGPDAETL 262
Score = 47.6 bits (108), Expect = 1e-04
Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
G +H+AC V LL +GA N G TPLH+C + CA+ LL G
Sbjct: 143 GRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATV 202
Query: 269 E-ALNFANQTPYQVAVIAG 286
A + +TP VA G
Sbjct: 203 NLAAGESQETPLHVAAARG 221
Score = 39.9 bits (89), Expect = 0.021
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A G HL+ GA+++AR G LH AQ C R LL G L
Sbjct: 118 ATARGYTDCARHLIRQGAELDAR-VGGRAALHEACARAQFDCVRLLLTFGAKANVLTEEG 176
Query: 276 QTPYQVAVIAGNLDLAEVI 294
TP + I +L A+++
Sbjct: 177 TTPLHLCTIPESLQCAKLL 195
>BC118584-1|AAI18585.1| 273|Homo sapiens ASB16 protein protein.
Length = 273
Score = 62.9 bits (146), Expect = 3e-09
Identities = 45/136 (33%), Positives = 64/136 (47%), Gaps = 5/136 (3%)
Query: 128 LVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTPLYLSVTNKT 187
L+ GA LD R G A+H A + + V+ LL GA N +G TPL+L ++
Sbjct: 130 LIRQGAELDARV-GGRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPES 188
Query: 188 DPLLC-ETLLHDHATIGATDLQGWQE-VHQACRNGLVQHVDHLLFYGADMNARNASGNTP 245
L C + LL AT+ + + +H A GL QHV L +GAD+ R + G T
Sbjct: 189 --LQCAKLLLEAGATVNLAAGESQETPLHVAAARGLEQHVALYLEHGADVGLRTSQGETA 246
Query: 246 LHVCAVNAQDSCARQL 261
L+ A+ A L
Sbjct: 247 LNTACAGAEGPDAETL 262
Score = 47.6 bits (108), Expect = 1e-04
Identities = 27/79 (34%), Positives = 35/79 (44%), Gaps = 1/79 (1%)
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
G +H+AC V LL +GA N G TPLH+C + CA+ LL G
Sbjct: 143 GRAALHEACARAQFDCVRLLLTFGAKANVLTEEGTTPLHLCTIPESLQCAKLLLEAGATV 202
Query: 269 E-ALNFANQTPYQVAVIAG 286
A + +TP VA G
Sbjct: 203 NLAAGESQETPLHVAAARG 221
Score = 39.9 bits (89), Expect = 0.021
Identities = 24/79 (30%), Positives = 33/79 (41%), Gaps = 1/79 (1%)
Query: 216 ACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFAN 275
A G HL+ GA+++AR G LH AQ C R LL G L
Sbjct: 118 ATARGYTDCARHLIRQGAELDAR-VGGRAALHEACARAQFDCVRLLLTFGAKANVLTEEG 176
Query: 276 QTPYQVAVIAGNLDLAEVI 294
TP + I +L A+++
Sbjct: 177 TTPLHLCTIPESLQCAKLL 195
>BC106000-1|AAI06001.1| 1663|Homo sapiens cortactin binding protein
2 protein.
Length = 1663
Score = 62.9 bits (146), Expect = 3e-09
Identities = 52/197 (26%), Positives = 85/197 (43%), Gaps = 8/197 (4%)
Query: 104 CQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRAVEKNSLEAVKTLL- 162
C+ L + A SP+ + + G A L R T + +A + ++ + LL
Sbjct: 676 CRPGASDSLLVTASGWSPSLTPLLMSGGPAPLAGRP----TLLQQAAAQGNVTLLSMLLN 731
Query: 163 ELGASPNYKDGKGLTPLYLSVTN-KTDPLLCETLLHDHATIGATDLQGWQEVHQACRNGL 221
E G NY G + LY + N TD + LL A + A D G+ + A G
Sbjct: 732 EEGLDINYSCEDGHSALYSAAKNGHTDCV--RLLLSAEAQVNAADKNGFTPLCAAAAQGH 789
Query: 222 VQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQV 281
+ V+ L+ Y A++N G TPL++ N C + LL G ++ TP
Sbjct: 790 FECVELLISYDANINHAADGGQTPLYLACKNGNKECIKLLLEAGTNRSVKTTDGWTPVHA 849
Query: 282 AVIAGNLDLAEVIKNYK 298
AV GN+D +++ ++
Sbjct: 850 AVDTGNVDSLKLLMYHR 866
Score = 33.5 bits (73), Expect = 1.9
Identities = 24/89 (26%), Positives = 38/89 (42%), Gaps = 1/89 (1%)
Query: 213 VHQACRNGLVQHVDHLLFY-GADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDKEAL 271
+ QA G V + LL G D+N G++ L+ A N C R LL A
Sbjct: 714 LQQAAAQGNVTLLSMLLNEEGLDINYSCEDGHSALYSAAKNGHTDCVRLLLSAEAQVNAA 773
Query: 272 NFANQTPYQVAVIAGNLDLAEVIKNYKSD 300
+ TP A G+ + E++ +Y ++
Sbjct: 774 DKNGFTPLCAAAAQGHFECVELLISYDAN 802
>AL596222-1|CAH70182.1| 2471|Homo sapiens Notch homolog 2 (Drosophila)
protein.
Length = 2471
Score = 62.9 bits (146), Expect = 3e-09
Identities = 50/180 (27%), Positives = 83/180 (46%), Gaps = 3/180 (1%)
Query: 120 SPAKILIALVNGGALLDYRT-RDGSTAMHRAVEKNSLEAVKTLLELGASPNYKDGKGLTP 178
S A I+ LV GA L +T R G A+H A + +A K LL+ GA N +D G P
Sbjct: 1854 SSANIITDLVYQGASLQAQTDRTGEMALHLAARYSRADAAKRLLDAGADANAQDNMGRCP 1913
Query: 179 LYLSVTNKTDPLLCETLLHDHAT-IGATDLQGWQEVHQACRNGLVQHVDHLLFYGADMNA 237
L+ +V + + L+ + T + A G + A R + V L+ AD+NA
Sbjct: 1914 LHAAVAADAQGVF-QILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAELINCQADVNA 1972
Query: 238 RNASGNTPLHVCAVNAQDSCARQLLFRGCDKEALNFANQTPYQVAVIAGNLDLAEVIKNY 297
+ G + LH A LL G +++ + +TP +A G+ + A+++ ++
Sbjct: 1973 VDDHGKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDH 2032
Score = 48.8 bits (111), Expect = 5e-05
Identities = 49/209 (23%), Positives = 88/209 (42%), Gaps = 3/209 (1%)
Query: 90 ITKACAKGLDPNFHCQETGETPLTIAAGLKSPAKILIALVNGGALLDYRTRDGSTAMHRA 149
IT +G TGE L +AA S A L++ GA + + G +H A
Sbjct: 1859 ITDLVYQGASLQAQTDRTGEMALHLAARY-SRADAAKRLLDAGADANAQDNMGRCPLHAA 1917
Query: 150 VEKNSLEAVKTLLELGASP-NYKDGKGLTPLYLSVTNKTDPLLCETLLHDHATIGATDLQ 208
V ++ + L+ + + + G TPL L+ + ++ E L++ A + A D
Sbjct: 1918 VAADAQGVFQILIRNRVTDLDARMNDGTTPLILAARLAVEGMVAE-LINCQADVNAVDDH 1976
Query: 209 GWQEVHQACRNGLVQHVDHLLFYGADMNARNASGNTPLHVCAVNAQDSCARQLLFRGCDK 268
G +H A V+ LL GA+ + ++ TPL + A A+ LL ++
Sbjct: 1977 GKSALHWAAAVNNVEATLLLLKNGANRDMQDNKEETPLFLAAREGSYEAAKILLDHFANR 2036
Query: 269 EALNFANQTPYQVAVIAGNLDLAEVIKNY 297
+ + ++ P VA + D+ ++ Y
Sbjct: 2037 DITDHMDRLPRDVARDRMHHDIVRLLDEY 2065
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.318 0.134 0.405
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 72,321,358
Number of Sequences: 224733
Number of extensions: 2901901
Number of successful extensions: 13718
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 918
Number of HSP's successfully gapped in prelim test: 187
Number of HSP's that attempted gapping in prelim test: 6097
Number of HSP's gapped (non-prelim): 4396
length of query: 523
length of database: 73,234,838
effective HSP length: 93
effective length of query: 430
effective length of database: 52,334,669
effective search space: 22503907670
effective search space used: 22503907670
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 67 (31.1 bits)
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