Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000843-TA|BGIBMGA000843-PA|IPR006202|Neurotransmitter-
gated ion-channel ligand-binding, IPR006028|Gamma-aminobutyric acid A
receptor, IPR006201|Neurotransmitter-gated ion-channel,
IPR006029|Neurotransmitter-gated ion-channel transmembrane region
(418 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8SWZ1 Cluster: RH55021p; n=4; Diptera|Rep: RH55021p - ... 588 e-166
UniRef50_Q0GQQ5 Cluster: Cys-loop ligand-gated ion channel subun... 488 e-136
UniRef50_UPI00015B5BFB Cluster: PREDICTED: similar to cys-loop l... 464 e-129
UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio ... 212 2e-53
UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3 precur... 208 3e-52
UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12; Endopteryg... 204 4e-51
UniRef50_P48167 Cluster: Glycine receptor subunit beta precursor... 193 6e-48
UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep: CG7... 186 7e-46
UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus urticae... 185 2e-45
UniRef50_Q09453 Cluster: Glycine receptor subunit beta-type 4 pr... 185 2e-45
UniRef50_A7SNP9 Cluster: Predicted protein; n=2; Nematostella ve... 184 4e-45
UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella ve... 184 4e-45
UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subuni... 184 4e-45
UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated... 179 1e-43
UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr) ... 179 1e-43
UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella ve... 177 6e-43
UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subuni... 177 6e-43
UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella ve... 175 1e-42
UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subuni... 175 2e-42
UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22; Eumeta... 173 5e-42
UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome sh... 170 5e-41
UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subuni... 170 7e-41
UniRef50_Q22741 Cluster: Putative uncharacterized protein; n=2; ... 169 9e-41
UniRef50_Q08832 Cluster: Gamma-aminobutyric acid receptor subuni... 169 1e-40
UniRef50_Q8MTJ9 Cluster: Ionotropic GABA receptor beta subunit 1... 169 2e-40
UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated chloride... 167 5e-40
UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subuni... 167 6e-40
UniRef50_A7RS31 Cluster: Predicted protein; n=1; Nematostella ve... 164 4e-39
UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subuni... 164 4e-39
UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subuni... 163 8e-39
UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated... 161 2e-38
UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis melli... 161 3e-38
UniRef50_O17547 Cluster: GluClalpha2A protein; n=66; Chromadorea... 161 3e-38
UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2; ... 160 5e-38
UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4; ... 160 7e-38
UniRef50_A7LPG1 Cluster: Putative uncharacterized protein; n=3; ... 159 2e-37
UniRef50_Q94900 Cluster: Glutamate-gated chloride channel precur... 159 2e-37
UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2; ... 158 3e-37
UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP125... 157 4e-37
UniRef50_P28476 Cluster: Gamma-aminobutyric acid receptor subuni... 157 5e-37
UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4; ... 157 7e-37
UniRef50_P78334 Cluster: Gamma-aminobutyric acid receptor subuni... 157 7e-37
UniRef50_O46123 Cluster: GBR-2A protein precursor; n=3; Chromado... 156 9e-37
UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella ve... 156 1e-36
UniRef50_Q9Y0I3 Cluster: Ionotropic GABA receptor subunit UNC-49... 155 2e-36
UniRef50_Q25035 Cluster: GABA A/glycine receptor subunit; n=3; R... 155 2e-36
UniRef50_A7SFV7 Cluster: Predicted protein; n=1; Nematostella ve... 155 2e-36
UniRef50_Q9N517 Cluster: Putative uncharacterized protein; n=2; ... 153 6e-36
UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1; ... 152 2e-35
UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to glutamate-... 151 4e-35
UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1; Apl... 151 4e-35
UniRef50_UPI0000E4758B Cluster: PREDICTED: similar to GABA-gated... 149 1e-34
UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to gamma-amin... 149 1e-34
UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2; ... 149 1e-34
UniRef50_A7SJ14 Cluster: Predicted protein; n=2; Nematostella ve... 149 1e-34
UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2; ... 149 2e-34
UniRef50_A7SAS4 Cluster: Predicted protein; n=2; Nematostella ve... 147 4e-34
UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subuni... 146 9e-34
UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subuni... 146 1e-33
UniRef50_UPI0000E48505 Cluster: PREDICTED: similar to inhibitory... 145 2e-33
UniRef50_Q17328 Cluster: Glutamate-gated chloride channel subuni... 145 2e-33
UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG023... 144 3e-33
UniRef50_A7S448 Cluster: Predicted protein; n=2; Nematostella ve... 144 5e-33
UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella ve... 144 5e-33
UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella ve... 143 7e-33
UniRef50_UPI00015B49D8 Cluster: PREDICTED: similar to cys-loop l... 142 2e-32
UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr) ... 142 2e-32
UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subuni... 141 3e-32
UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1; ... 141 4e-32
UniRef50_A7SAV3 Cluster: Predicted protein; n=1; Nematostella ve... 140 5e-32
UniRef50_A7SCG4 Cluster: Predicted protein; n=1; Nematostella ve... 139 1e-31
UniRef50_Q9TZI5 Cluster: Expulsion defective (Defecation) protei... 138 2e-31
UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;... 138 2e-31
UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3; ... 138 3e-31
UniRef50_A7RZG9 Cluster: Predicted protein; n=3; Nematostella ve... 137 6e-31
UniRef50_Q17KW1 Cluster: Glycine receptor beta, putative; n=1; A... 136 8e-31
UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2; ... 136 1e-30
UniRef50_UPI0000D56CB6 Cluster: PREDICTED: similar to CG6927-PA;... 135 2e-30
UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella ve... 134 5e-30
UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like p... 132 1e-29
UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella ve... 132 2e-29
UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella ve... 132 2e-29
UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subun... 131 3e-29
UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor... 130 5e-29
UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;... 129 2e-28
UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella ve... 128 2e-28
UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella ve... 128 3e-28
UniRef50_Q95QT7 Cluster: Glutamate-gated chloride channel protei... 128 4e-28
UniRef50_UPI000065FF28 Cluster: Gamma-aminobutyric-acid receptor... 127 5e-28
UniRef50_Q0GQQ4 Cluster: Cys-loop ligand-gated ion channel subun... 127 6e-28
UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whol... 126 1e-27
UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella ve... 126 1e-27
UniRef50_UPI0000D56CB7 Cluster: PREDICTED: similar to CG6927-PA;... 125 2e-27
UniRef50_Q4SKT9 Cluster: Chromosome undetermined SCAF14565, whol... 124 3e-27
UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila ... 124 6e-27
UniRef50_Q2PDY9 Cluster: CG33989-PF, isoform F; n=16; Endopteryg... 124 6e-27
UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric ac... 123 1e-26
UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep: CG1134... 122 2e-26
UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA ... 120 9e-26
UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella ve... 119 1e-25
UniRef50_O17041 Cluster: Putative uncharacterized protein T15B7.... 119 2e-25
UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella ve... 119 2e-25
UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella ve... 118 2e-25
UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2; ... 118 3e-25
UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1; D... 116 1e-24
UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella ve... 115 3e-24
UniRef50_P90876 Cluster: Putative uncharacterized protein; n=2; ... 114 4e-24
UniRef50_UPI0000F1E22C Cluster: PREDICTED: hypothetical protein;... 105 2e-21
UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor alpha-... 100 6e-20
UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2; ... 100 1e-19
UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4... 100 1e-19
UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whol... 97 1e-18
UniRef50_UPI0000ECC613 Cluster: Gamma-aminobutyric-acid receptor... 87 6e-16
UniRef50_A0YQU9 Cluster: Putative uncharacterized protein; n=1; ... 85 2e-15
UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG067... 84 6e-15
UniRef50_Q45U92 Cluster: GABA-A receptor; n=3; Caenorhabditis|Re... 83 1e-14
UniRef50_A7SCG3 Cluster: Predicted protein; n=1; Nematostella ve... 82 3e-14
UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel liga... 79 2e-13
UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella ve... 79 2e-13
UniRef50_UPI0000D9B066 Cluster: PREDICTED: gamma-aminobutyric ac... 77 9e-13
UniRef50_A6FXF8 Cluster: Putative uncharacterized protein; n=1; ... 76 2e-12
UniRef50_A7NAE6 Cluster: Neurotransmitter-gated ion-channel liga... 76 2e-12
UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome sh... 75 3e-12
UniRef50_UPI00015ADFAB Cluster: hypothetical protein NEMVEDRAFT_... 74 8e-12
UniRef50_A7SAR5 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 73 1e-11
UniRef50_Q70GM3 Cluster: Ligand-gated chloride channel subunit p... 72 3e-11
UniRef50_A7SQS7 Cluster: Predicted protein; n=1; Nematostella ve... 69 2e-10
UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter viola... 69 3e-10
UniRef50_A4CWI3 Cluster: Putative uncharacterized protein; n=1; ... 67 9e-10
UniRef50_Q4RNA9 Cluster: Chromosome 1 SCAF15015, whole genome sh... 64 9e-09
UniRef50_A7SQS5 Cluster: Predicted protein; n=1; Nematostella ve... 63 1e-08
UniRef50_Q4SXG5 Cluster: Chromosome undetermined SCAF12416, whol... 63 2e-08
UniRef50_UPI0000EBED4A Cluster: PREDICTED: similar to gamma-amin... 62 2e-08
UniRef50_Q18556 Cluster: Putative uncharacterized protein acr-9;... 61 5e-08
UniRef50_A7SW63 Cluster: Predicted protein; n=3; Nematostella ve... 61 6e-08
UniRef50_A7SI11 Cluster: Predicted protein; n=1; Nematostella ve... 60 1e-07
UniRef50_A7S2J7 Cluster: Predicted protein; n=1; Nematostella ve... 57 7e-07
UniRef50_Q4T6F3 Cluster: Chromosome 7 SCAF8790, whole genome sho... 56 1e-06
UniRef50_UPI0000E48B7E Cluster: PREDICTED: similar to neuronal n... 56 2e-06
UniRef50_P11230 Cluster: Acetylcholine receptor subunit beta pre... 54 5e-06
UniRef50_A6FMG2 Cluster: Putative uncharacterized protein; n=1; ... 54 7e-06
UniRef50_Q9NA46 Cluster: Putative uncharacterized protein acr-24... 54 7e-06
UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD) alt... 54 9e-06
UniRef50_Q2XWK7 Cluster: Nicotinic acetylcholine receptor subuni... 54 9e-06
UniRef50_P48180 Cluster: Acetylcholine receptor subunit alpha-ty... 54 9e-06
UniRef50_P48182 Cluster: Acetylcholine receptor subunit beta-typ... 53 1e-05
UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2;... 53 2e-05
UniRef50_P91197 Cluster: Acetylcholine receptor protein 11; n=2;... 52 2e-05
UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor ... 52 2e-05
UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG104... 52 3e-05
UniRef50_A7RHV9 Cluster: Predicted protein; n=3; Nematostella ve... 51 5e-05
UniRef50_Q7T2S3 Cluster: Nicotinic acetylcholine receptor alpha ... 51 7e-05
UniRef50_UPI0001560C7D Cluster: PREDICTED: similar to cholinergi... 50 9e-05
UniRef50_A7RK99 Cluster: Predicted protein; n=2; Nematostella ve... 50 9e-05
UniRef50_P45963 Cluster: Acetylcholine receptor subunit alpha-ty... 50 9e-05
UniRef50_Q4S3I6 Cluster: Chromosome 1 SCAF14749, whole genome sh... 50 1e-04
UniRef50_A7S622 Cluster: Predicted protein; n=1; Nematostella ve... 50 1e-04
UniRef50_UPI0000F1DA85 Cluster: PREDICTED: similar to MGC52789 p... 50 2e-04
UniRef50_P43681 Cluster: Neuronal acetylcholine receptor subunit... 50 2e-04
UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-ty... 50 2e-04
UniRef50_A7S8Q4 Cluster: Predicted protein; n=3; Nematostella ve... 49 3e-04
UniRef50_P36544 Cluster: Neuronal acetylcholine receptor subunit... 49 3e-04
UniRef50_A7RR86 Cluster: Predicted protein; n=1; Nematostella ve... 48 3e-04
UniRef50_O46132 Cluster: Nicotinic acetylcholine receptor, alpha... 48 5e-04
UniRef50_A7RLM4 Cluster: Predicted protein; n=2; Nematostella ve... 48 5e-04
UniRef50_Q15822 Cluster: Neuronal acetylcholine receptor subunit... 48 5e-04
UniRef50_Q2XWL0 Cluster: Nicotinic acetylcholine receptor subuni... 48 6e-04
UniRef50_O61884 Cluster: Acetylcholine receptor protein 23; n=2;... 48 6e-04
UniRef50_A7RNN1 Cluster: Predicted protein; n=2; Nematostella ve... 48 6e-04
UniRef50_A7RNI2 Cluster: Predicted protein; n=3; Nematostella ve... 48 6e-04
UniRef50_A7RLP3 Cluster: Predicted protein; n=3; Nematostella ve... 48 6e-04
UniRef50_P46098 Cluster: 5-hydroxytryptamine receptor 3 precurso... 48 6e-04
UniRef50_Q4S864 Cluster: Chromosome 5 SCAF14709, whole genome sh... 47 8e-04
UniRef50_Q5BW84 Cluster: SJCHGC08361 protein; n=1; Schistosoma j... 47 8e-04
UniRef50_Q2XWK8 Cluster: Nicotinic acetylcholine receptor subuni... 47 8e-04
UniRef50_P04755 Cluster: Acetylcholine receptor subunit beta-lik... 47 8e-04
UniRef50_UPI0000EBE733 Cluster: PREDICTED: similar to nicotinic ... 47 0.001
UniRef50_P54245 Cluster: Uncharacterized acetylcholine receptor-... 47 0.001
UniRef50_UPI00015B4DDF Cluster: PREDICTED: similar to neurotrans... 46 0.001
UniRef50_Q4RIA9 Cluster: Chromosome 8 SCAF15044, whole genome sh... 46 0.001
UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subuni... 46 0.001
UniRef50_Q4RU50 Cluster: Chromosome 1 SCAF14995, whole genome sh... 46 0.002
UniRef50_Q9UGM1 Cluster: Neuronal acetylcholine receptor subunit... 46 0.002
UniRef50_UPI00015A4976 Cluster: 5-hydroxytryptamine receptor 3 s... 46 0.002
UniRef50_O95264 Cluster: 5-hydroxytryptamine 3B receptor precurs... 46 0.002
UniRef50_UPI0000E47621 Cluster: PREDICTED: similar to nicotinic ... 45 0.004
UniRef50_UPI00015A3E3C Cluster: Neuronal acetylcholine receptor ... 45 0.004
UniRef50_Q9GP98 Cluster: Acetylcholine receptor protein 22; n=3;... 45 0.004
UniRef50_Q65XS8 Cluster: Acetylcholine receptor protein 25; n=2;... 45 0.004
UniRef50_UPI0000F1E62D Cluster: PREDICTED: hypothetical protein;... 44 0.006
UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3 s... 44 0.006
UniRef50_A7S9T8 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.006
UniRef50_A7S2P0 Cluster: Predicted protein; n=4; Nematostella ve... 44 0.006
UniRef50_A7RS32 Cluster: Predicted protein; n=1; Nematostella ve... 44 0.006
UniRef50_UPI0000E49087 Cluster: PREDICTED: similar to Glra4a pro... 44 0.007
UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal a... 44 0.007
UniRef50_Q9N5U8 Cluster: Acetylcholine receptor protein 21; n=2;... 44 0.007
UniRef50_Q6Q069 Cluster: Neuronal nicotinic acetylcholine Apisa7... 44 0.007
UniRef50_UPI0000E49402 Cluster: PREDICTED: similar to alpha 10 s... 43 0.013
UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA... 43 0.013
UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2;... 43 0.013
UniRef50_Q2XWL1 Cluster: Nicotinic acetylcholine receptor subuni... 43 0.013
UniRef50_O61216 Cluster: Ligand-gated ion channel protein 30; n=... 43 0.013
UniRef50_A7I712 Cluster: Putative uncharacterized protein precur... 43 0.013
UniRef50_P17787 Cluster: Neuronal acetylcholine receptor subunit... 43 0.013
UniRef50_A7RFJ5 Cluster: Predicted protein; n=2; Nematostella ve... 43 0.017
UniRef50_A2TM48 Cluster: Nicotinic acetylcholine receptor alpha ... 43 0.017
UniRef50_Q04844 Cluster: Acetylcholine receptor subunit epsilon ... 43 0.017
UniRef50_Q66T35 Cluster: Nicotinic acetylcholine receptor subuni... 42 0.023
UniRef50_A7RJP2 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.023
UniRef50_UPI0000E49D12 Cluster: PREDICTED: similar to acetylchol... 42 0.030
UniRef50_Q9XTY8 Cluster: Putative uncharacterized protein lgc-25... 42 0.030
UniRef50_Q29ND1 Cluster: GA17977-PA; n=3; Schizophora|Rep: GA179... 42 0.030
UniRef50_UPI0000E4930A Cluster: PREDICTED: similar to nicotinic ... 42 0.040
UniRef50_Q4SGK0 Cluster: Chromosome 3 SCAF14593, whole genome sh... 42 0.040
UniRef50_O62083 Cluster: Putative uncharacterized protein acr-19... 42 0.040
UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma pr... 42 0.040
UniRef50_P30532 Cluster: Neuronal acetylcholine receptor subunit... 42 0.040
UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-ty... 42 0.040
UniRef50_Q2IWF4 Cluster: Neurotransmitter-gated ion-channel liga... 41 0.053
UniRef50_Q9XTE5 Cluster: Putative uncharacterized protein lgc-31... 41 0.053
UniRef50_P54244 Cluster: Acetylcholine receptor subunit alpha-ty... 41 0.053
UniRef50_Q7T2R4 Cluster: Nicotinic acetylcholine receptor alpha ... 41 0.070
UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isof... 41 0.070
UniRef50_Q2XWK4 Cluster: Nicotinic acetylcholine receptor subuni... 41 0.070
UniRef50_A7S9T6 Cluster: Predicted protein; n=2; Nematostella ve... 41 0.070
UniRef50_UPI00015B4A35 Cluster: PREDICTED: similar to nicotinic ... 40 0.092
UniRef50_UPI000041A8E7 Cluster: PREDICTED: similar to Gamma-amin... 40 0.092
UniRef50_A7T7Z5 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.12
UniRef50_P91766 Cluster: Acetylcholine receptor subunit alpha-li... 40 0.12
UniRef50_UPI0000E47C59 Cluster: PREDICTED: similar to alpha-9 ni... 40 0.16
UniRef50_UPI0000ECB6ED Cluster: Acetylcholine receptor subunit a... 40 0.16
UniRef50_Q6TMY0 Cluster: Nicotinic acetylcholine receptor non-al... 40 0.16
UniRef50_A7RFJ2 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.16
UniRef50_UPI0000D55E50 Cluster: PREDICTED: similar to AcetylChol... 39 0.21
UniRef50_Q5BZP4 Cluster: SJCHGC07923 protein; n=1; Schistosoma j... 39 0.21
UniRef50_Q22224 Cluster: Putative uncharacterized protein acr-14... 39 0.21
UniRef50_UPI0000E45D33 Cluster: PREDICTED: similar to nicotinic ... 39 0.28
UniRef50_Q4SRT3 Cluster: Chromosome undetermined SCAF14492, whol... 39 0.28
UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha ... 39 0.28
UniRef50_Q8JFN7 Cluster: Neuronal acetylcholine receptor subunit... 39 0.28
UniRef50_P25162 Cluster: Acetylcholine receptor subunit beta-lik... 39 0.28
UniRef50_UPI00006602DC Cluster: Homolog of Homo sapiens "5-hydro... 38 0.37
UniRef50_Q4RRI3 Cluster: Chromosome 16 SCAF15002, whole genome s... 38 0.37
UniRef50_P17644 Cluster: Acetylcholine receptor subunit alpha-li... 38 0.37
UniRef50_UPI0000E4906A Cluster: PREDICTED: similar to nicotinic ... 38 0.49
UniRef50_UPI00006A0062 Cluster: UPI00006A0062 related cluster; n... 38 0.49
UniRef50_UPI00006603C6 Cluster: Homolog of Homo sapiens "5-hydro... 38 0.49
UniRef50_Q4S3I4 Cluster: Chromosome 1 SCAF14749, whole genome sh... 38 0.49
UniRef50_UPI0000E49844 Cluster: PREDICTED: similar to nicotinic ... 38 0.65
UniRef50_UPI0000E47C58 Cluster: PREDICTED: similar to nicotinic ... 38 0.65
UniRef50_UPI0000660F16 Cluster: Homolog of Homo sapiens "Splice ... 38 0.65
UniRef50_Q2XWK5 Cluster: Nicotinic acetylcholine receptor subuni... 38 0.65
UniRef50_UPI0000E464AB Cluster: PREDICTED: similar to nicotinic ... 37 0.86
UniRef50_UPI000065F0EC Cluster: Homolog of Homo sapiens "5-hydro... 37 0.86
UniRef50_Q4RR58 Cluster: Chromosome 14 SCAF15003, whole genome s... 37 0.86
UniRef50_A7RTX5 Cluster: Predicted protein; n=1; Nematostella ve... 37 0.86
UniRef50_Q07001 Cluster: Acetylcholine receptor subunit delta pr... 37 0.86
UniRef50_UPI000069FF34 Cluster: UPI000069FF34 related cluster; n... 37 1.1
UniRef50_Q7KT97 Cluster: CG32975-PB, isoform B; n=69; Eumetazoa|... 37 1.1
UniRef50_Q6U4B5 Cluster: Nicotinic acetylcholine receptor beta 1... 37 1.1
UniRef50_Q66T21 Cluster: Nicotinic acetylcholine receptor subuni... 37 1.1
UniRef50_O44452 Cluster: Putative uncharacterized protein; n=2; ... 37 1.1
UniRef50_A5H038 Cluster: Nicotinic acetylcholine receptor subuni... 37 1.1
UniRef50_Q60S81 Cluster: Neuronal acetylcholine receptor subunit... 37 1.1
UniRef50_UPI00015B5C6B Cluster: PREDICTED: similar to nicotinic ... 36 1.5
UniRef50_Q7ZTN5 Cluster: MGC52789 protein; n=1; Xenopus laevis|R... 36 1.5
UniRef50_Q4RZC6 Cluster: Chromosome 1 SCAF14944, whole genome sh... 36 1.5
UniRef50_Q2XWL2 Cluster: Nicotinic acetylcholine receptor subuni... 36 1.5
UniRef50_Q2XWK3 Cluster: Nicotinic acetylcholine receptor subuni... 36 1.5
UniRef50_Q4SRT2 Cluster: Chromosome undetermined SCAF14492, whol... 36 2.0
UniRef50_Q9GUF0 Cluster: Ligand-gated ion channel protein 10; n=... 36 2.0
UniRef50_A7S3F7 Cluster: Predicted protein; n=1; Nematostella ve... 36 2.0
UniRef50_A7RUG1 Cluster: Predicted protein; n=2; Nematostella ve... 36 2.0
UniRef50_A0EIZ7 Cluster: Nicotinic acetylcholine receptor alpha9... 36 2.0
UniRef50_A4TVG5 Cluster: Glycine receptor, alpha 4 subunit; n=1;... 36 2.6
UniRef50_Q17BK7 Cluster: Nicotinic acetylcholine receptor, beta-... 36 2.6
UniRef50_P02708 Cluster: Acetylcholine receptor subunit alpha pr... 36 2.6
UniRef50_UPI0000E47720 Cluster: PREDICTED: similar to alpha-9 ni... 35 3.5
UniRef50_UPI000065DFE4 Cluster: 5-hydroxytryptamine 3 receptor p... 35 3.5
UniRef50_A5JYS3 Cluster: Putative uncharacterized protein lgc-24... 35 3.5
UniRef50_UPI0000E48474 Cluster: PREDICTED: similar to nicotinic ... 35 4.6
UniRef50_Q4RU52 Cluster: Chromosome 1 SCAF14995, whole genome sh... 35 4.6
UniRef50_Q8EW95 Cluster: Putative uncharacterized protein MYPE30... 35 4.6
UniRef50_Q2XWK9 Cluster: Nicotinic acetylcholine receptor subuni... 35 4.6
UniRef50_UPI0000F2C37E Cluster: PREDICTED: similar to CHRNG prot... 34 6.0
UniRef50_UPI0000F1DB4B Cluster: PREDICTED: hypothetical protein;... 34 6.0
UniRef50_UPI0000E49401 Cluster: PREDICTED: similar to alpha 10 s... 34 6.0
UniRef50_Q4W520 Cluster: Putative uncharacterized protein; n=1; ... 34 6.0
UniRef50_UPI0000E477D1 Cluster: PREDICTED: similar to nicotinic ... 34 8.0
UniRef50_UPI0000584BCE Cluster: PREDICTED: hypothetical protein;... 34 8.0
UniRef50_UPI0000499714 Cluster: protein kinase; n=3; Entamoeba h... 34 8.0
UniRef50_Q54LC8 Cluster: Putative uncharacterized protein; n=1; ... 34 8.0
UniRef50_O17848 Cluster: Putative uncharacterized protein acr-18... 34 8.0
UniRef50_P78820 Cluster: Acetyl-CoA carboxylase (EC 6.4.1.2) (AC... 34 8.0
UniRef50_Q9U298 Cluster: Neuronal acetylcholine receptor subunit... 34 8.0
>UniRef50_Q8SWZ1 Cluster: RH55021p; n=4; Diptera|Rep: RH55021p -
Drosophila melanogaster (Fruit fly)
Length = 449
Score = 588 bits (1451), Expect = e-166
Identities = 277/415 (66%), Positives = 325/415 (78%), Gaps = 15/415 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RPP++KG PVIV+FSI+VVD+NSINVEDMDFRVDMFI Q W ESRL++P+DIFEEGDD+
Sbjct: 48 IRPPSKKGSPVIVDFSIFVVDINSINVEDMDFRVDMFIHQRWLESRLEIPDDIFEEGDDY 107
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
VTL PE F+N W PDPYFLNSK+ EIA LTHKF+SVTLY+N+TVRY+ARMHAIIACQMEF
Sbjct: 108 VTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQMEF 167
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
QLYPMDIQ CPIYIESFS +NQKV+ RWS++GVT+NPELKLLQY++GQPL LEE++GYM
Sbjct: 168 QLYPMDIQVCPIYIESFSSNNQKVKLRWSDSGVTLNPELKLLQYNLGQPLELEESDGYMP 227
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
+K GN+SRL VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL LDAIPGR
Sbjct: 228 EKVGNFSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRVTLLVTCML 287
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQES 300
FTG ADIPPVAYVKALDLWMAGCM+ VFAAL EFVVVKVLD QYQ N+
Sbjct: 288 TLVTMFTG--ADIPPVAYVKALDLWMAGCMLSVFAALAEFVVVKVLDVQYQYQVNR---- 341
Query: 301 MPRIIPVRL-NGDKGSCGTIAAWEGSGVRCRKVDIXXXXXXXXXXXXXXXXXXXXXXXXX 359
+P+++P+R+ N +KG C T+A+WEG VR RK
Sbjct: 342 IPKVLPMRISNMEKGQCATVASWEGGAVRSRK--------ATQTPTTPGQTSLQGNGGPP 393
Query: 360 GVERRQSILQVAWLDADTGQERVLWREIDKLSRVVFPALFLLFVTMYWPVLLLKT 414
RRQS+L VAW D DTG E+++WREIDK+SR VFP LF +FV +YWP+LL+K+
Sbjct: 394 KPARRQSLLSVAWTDTDTGVEKIMWREIDKVSRAVFPILFFVFVLLYWPILLMKS 448
>UniRef50_Q0GQQ5 Cluster: Cys-loop ligand-gated ion channel subunit;
n=3; Endopterygota|Rep: Cys-loop ligand-gated ion
channel subunit - Apis mellifera (Honeybee)
Length = 391
Score = 488 bits (1203), Expect = e-136
Identities = 222/303 (73%), Positives = 256/303 (84%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RPP+++G PV+V+F+I+V D+NSINVEDMDFRVDMF+RQ+W ESRL +P+ IFEEGDD+
Sbjct: 1 IRPPSKQGLPVLVDFNIFVADINSINVEDMDFRVDMFVRQSWIESRLDMPDYIFEEGDDY 60
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
VTLPPEFFD+LW PDPYFLN+KV+EIA L HKFSSVTLYRN+TV+YSARMHAIIACQMEF
Sbjct: 61 VTLPPEFFDSLWQPDPYFLNAKVSEIAALNHKFSSVTLYRNKTVKYSARMHAIIACQMEF 120
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
QLYPMDIQ CPIYIESFSY QK+R RW VT+NPELKLLQY IG+P+ EET YM+
Sbjct: 121 QLYPMDIQICPIYIESFSYHKQKLRLRWGTGAVTVNPELKLLQYDIGKPVVAEETVDYML 180
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
+K GN+SRLVV+FRFERQIGHHLIQTFAPS+LVVMLSWFSFWL LDAIPGR
Sbjct: 181 EKSGNFSRLVVFFRFERQIGHHLIQTFAPSTLVVMLSWFSFWLGLDAIPGRVALLVTSML 240
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQES 300
FTGL++DIPPVAYVKALD+WMAGCMMFVFAALGEFVVVKVLD + Q+ +
Sbjct: 241 TLVTMFTGLKSDIPPVAYVKALDVWMAGCMMFVFAALGEFVVVKVLDLRSQLEYDLQTSI 300
Query: 301 MPR 303
M R
Sbjct: 301 MSR 303
Score = 46.8 bits (106), Expect = 0.001
Identities = 23/50 (46%), Positives = 31/50 (62%), Gaps = 3/50 (6%)
Query: 367 ILQVAWLDADTGQERVLWRE---IDKLSRVVFPALFLLFVTMYWPVLLLK 413
+LQ WLD + RV + ID SR+ FP LF+LF+ +YWP+LL K
Sbjct: 339 LLQNTWLDPEYPMIRVHKTQSQTIDIYSRIGFPILFMLFIILYWPILLFK 388
>UniRef50_UPI00015B5BFB Cluster: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit - Nasonia vitripennis
Length = 435
Score = 464 bits (1143), Expect = e-129
Identities = 215/310 (69%), Positives = 254/310 (81%), Gaps = 2/310 (0%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RPP PV+V F+I+VVD+NSINVEDMDFRVDMFI QTW+ESRL++P DIFE+ +D+
Sbjct: 46 IRPPTTGRTPVVVSFNIFVVDINSINVEDMDFRVDMFIYQTWTESRLRMPIDIFEDDEDY 105
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
VTLPPEFFDNLW PDPYFLNSKV+EIA L K SSVTLYRN+TVRYSARMHAIIACQMEF
Sbjct: 106 VTLPPEFFDNLWQPDPYFLNSKVSEIATLNSKHSSVTLYRNKTVRYSARMHAIIACQMEF 165
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
Q YPMDIQ CP+ IESFSY ++K+ RW GV +NPELKLLQY++ PL+++E+ ++
Sbjct: 166 QFYPMDIQICPMQIESFSYDSEKLSLRWGPDGVIVNPELKLLQYNLEDPLKIDESVSFID 225
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
+K+GN+SRL+VYF+FERQIGHHLIQTFAPS+LVVMLSWFSFWL LDAIPGR
Sbjct: 226 EKNGNFSRLIVYFQFERQIGHHLIQTFAPSTLVVMLSWFSFWLGLDAIPGRVALLVTSML 285
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQES 300
FTGL++DIPPVAYVKALDLWMAGCM FVF+ALGEFVVVKVLD YQ + +A S
Sbjct: 286 TLVTMFTGLKSDIPPVAYVKALDLWMAGCMFFVFSALGEFVVVKVLDLDYQ-RECEASNS 344
Query: 301 MPRIIPVRLN 310
R +P RL+
Sbjct: 345 YRR-LPARLS 353
Score = 48.0 bits (109), Expect = 5e-04
Identities = 24/53 (45%), Positives = 33/53 (62%), Gaps = 2/53 (3%)
Query: 365 QSILQVAWLDADTGQERVLWR--EIDKLSRVVFPALFLLFVTMYWPVLLLKTK 415
+++LQ W+D + R R +ID SRVVFP LFL+F +YWP LLL +
Sbjct: 380 RNLLQNTWIDPEILIRRPKNRAKQIDAYSRVVFPVLFLVFTLLYWPSLLLDNR 432
>UniRef50_A2BGE6 Cluster: Glycine receptor, alpha 4b; n=5; Danio
rerio|Rep: Glycine receptor, alpha 4b - Danio rerio
(Zebrafish) (Brachydanio rerio)
Length = 536
Score = 212 bits (517), Expect = 2e-53
Identities = 108/291 (37%), Positives = 167/291 (57%), Gaps = 11/291 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+R+++F+RQ W++ RL E DD + L
Sbjct: 107 PNFKGPPVNVTCNIFINSFGSITETTMDYRLNVFLRQQWNDPRLAYKE----YPDDSLDL 162
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K E+T + +++N V YS R+ I++C M+ + +
Sbjct: 163 DPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFQNGNVLYSIRLTLILSCPMDLKNF 222
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNGYMID- 181
PMD Q+C + +ESF Y+ + F+W + G V + +L L Q+ L+ E+ GY
Sbjct: 223 PMDTQTCTMQLESFGYTMNDLIFQWLDEGPVQVADDLMLPQF----VLKEEKDLGYCTKH 278
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G ++ + V F ERQ+G++LIQ + PS L V+LSW SFW+++DA P R
Sbjct: 279 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLTVILSWVSFWINMDAAPARVGLGITTVL 338
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ V + +QY+
Sbjct: 339 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQYK 389
>UniRef50_O75311 Cluster: Glycine receptor subunit alpha-3
precursor; n=128; Euteleostomi|Rep: Glycine receptor
subunit alpha-3 precursor - Homo sapiens (Human)
Length = 464
Score = 208 bits (507), Expect = 3e-52
Identities = 104/289 (35%), Positives = 164/289 (56%), Gaps = 7/289 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL E DD + L
Sbjct: 63 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE----YPDDSLDL 118
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K E+T + +++N V YS R+ ++C M+ + +
Sbjct: 119 DPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNF 178
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWS-EAGVTINPELKLLQYHIGQPLRLEETNGYMIDK 182
PMD+Q+C + +ESF Y+ + F W EA V + L L Q+ + + L +
Sbjct: 179 PMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHY--N 236
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 237 TGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTM 296
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVF+AL E+ V + +Q++
Sbjct: 297 TTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK 345
>UniRef50_Q9VGI0 Cluster: CG14723-PA, isoform A; n=12;
Endopterygota|Rep: CG14723-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 426
Score = 204 bits (497), Expect = 4e-51
Identities = 98/283 (34%), Positives = 165/283 (58%), Gaps = 7/283 (2%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
R P GQP +V F + V+ ++SIN E M + D+F+ Q+W + RL+LPE++ E+ +
Sbjct: 71 RAPKLLGQPTVVYFHVTVLSLDSINEESMTYVTDIFLAQSWRDPRLRLPENMSEQ---YR 127
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
L ++ ++W PD +F N+K E++ + LY ++T+ Y +++ +++C M+F+
Sbjct: 128 ILDVDWLHSIWRPDCFFKNAKKVTFHEMSIPNHYLWLYHDKTLLYMSKLTLVLSCAMKFE 187
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNGYMI 180
YP D Q C + IES S++ + + F W+ + +N E++L Q I + T Y
Sbjct: 188 SYPHDTQICSMMIESLSHTVEDLVFIWNMTDPLVVNTEIELPQLDISNNYTTDCTIEY-- 245
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
GN++ L + F R++G+HL T+ PS+L+V++SW SFW+ +AIP R
Sbjct: 246 -STGNFTCLAIVFNLRRRLGYHLFHTYIPSALIVVMSWISFWIKPEAIPARVTLGVTSLL 304
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
T + +PPV+YVKA+D+WM+ C +FVF +L EF VV
Sbjct: 305 TLATQNTQSQQSLPPVSYVKAIDVWMSSCSVFVFLSLMEFAVV 347
>UniRef50_P48167 Cluster: Glycine receptor subunit beta precursor;
n=34; Euteleostomi|Rep: Glycine receptor subunit beta
precursor - Homo sapiens (Human)
Length = 497
Score = 193 bits (471), Expect = 6e-48
Identities = 99/284 (34%), Positives = 158/284 (55%), Gaps = 4/284 (1%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL+LP D G D +T+
Sbjct: 73 PNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDF--RGSDALTV 130
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P + LW PD +F N K ++T + + ++R+ V S R+ ++C ++ L+
Sbjct: 131 DPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLF 190
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD 183
PMD Q C + +ESF Y+ +RF W ++ L Q+ I + +E N K
Sbjct: 191 PMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKE-DIEYGNCTKYYKG 249
Query: 184 -GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+ + V F RQ+G +++ +AP+ L+V+LSW SFW++ DA R
Sbjct: 250 TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSL 309
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T L A++P V+YVKALD+W+ C++F FA+L E+ VV+V+
Sbjct: 310 ASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVM 353
>UniRef50_Q9VDU9 Cluster: CG7411-PA; n=12; Endopterygota|Rep:
CG7411-PA - Drosophila melanogaster (Fruit fly)
Length = 485
Score = 186 bits (454), Expect = 7e-46
Identities = 90/303 (29%), Positives = 167/303 (55%), Gaps = 7/303 (2%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
MRPP ++GQP IV F + V+ ++SI+ M + D+F QTW + RL+LPE++ +E +
Sbjct: 43 MRPPKKEGQPTIVYFHVTVMGLDSIDENSMTYVADVFFAQTWKDHRLRLPENMTQE---Y 99
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
L ++ N+W PD +F N+K +T + LY+++T+ Y ++ ++C M F
Sbjct: 100 RLLEVDWLKNMWRPDSFFKNAKSVTFQTMTIPNHYMWLYKDKTILYMVKLTLKLSCIMNF 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNGYM 179
+YP D Q C + +ES S++ + F+W + ++ ++L Q + +R E +
Sbjct: 160 AIYPHDTQECKLQMESLSHTTDDLIFQWDPTTPLVVDENIELPQVAL---IRNETADCTQ 216
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
+ GN++ L V F +R++ +++ T+ P+ ++V++SW SFW+ +A P R
Sbjct: 217 VYSTGNFTCLEVVFTLKRRLVYYVFNTYIPTCMIVIMSWVSFWIKPEAAPARVTLGVTSL 276
Query: 240 XXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQE 299
++ +PPV+Y+KA+D +M+ C +FVF AL E+ ++ ++ + K A
Sbjct: 277 LTLSTQHAKSQSSLPPVSYLKAVDAFMSVCTVFVFMALMEYCLINIVLSDTPIPKPMAYP 336
Query: 300 SMP 302
P
Sbjct: 337 PKP 339
>UniRef50_Q2PMX5 Cluster: GABA receptor; n=1; Tetranychus
urticae|Rep: GABA receptor - Tetranychus urticae
(Two-spotted spider mite)
Length = 585
Score = 185 bits (451), Expect = 2e-45
Identities = 95/297 (31%), Positives = 154/297 (51%), Gaps = 7/297 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G PV V +++++ ++S++ MDF D + RQ W +SRL G + +
Sbjct: 63 PIMVGPPVKVGVTMHILTISSVSEVQMDFTADFYFRQLWRDSRLSFKA---RHGISQILV 119
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
E D +W PD +F N K E T K + + + + V S R+ +C M Q +
Sbjct: 120 DAEVADKIWVPDTFFANEKQAYFHEATTKNTFLRISHDGQVLRSIRLTVTASCPMNLQYF 179
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDK 182
PMD Q C I IES+ YS + + W E V I+ L L Q+ I + ++ Y+
Sbjct: 180 PMDRQKCNIEIESYGYSMTDIIYNWVDENAVKIDSNLMLPQFSIAS---IRQSWKYISLT 236
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
GNYSRL+ + R +G+++IQ + P+SL+V++SW SFWL +A P R
Sbjct: 237 TGNYSRLMCEIQLTRSMGYYMIQIYVPASLIVIISWVSFWLHRNATPARVHLGVITVLTM 296
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQE 299
+ + +P ++YVK++D+++ C + VFAAL E+ V + K+ M KN+ Q+
Sbjct: 297 TTLMSSTNSQLPKISYVKSIDVFLGTCFVMVFAALLEYAAVGYIGKRISMRKNRFQQ 353
Score = 36.3 bits (80), Expect = 1.5
Identities = 15/26 (57%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+IDK SRVVFP F+ F MYW + L
Sbjct: 546 DIDKYSRVVFPVCFVCFNLMYWIIFL 571
>UniRef50_Q09453 Cluster: Glycine receptor subunit beta-type 4
precursor; n=2; Caenorhabditis|Rep: Glycine receptor
subunit beta-type 4 precursor - Caenorhabditis elegans
Length = 473
Score = 185 bits (450), Expect = 2e-45
Identities = 89/272 (32%), Positives = 148/272 (54%), Gaps = 9/272 (3%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V+ +Y+ ++S + + MDF+VD++ ++ W + RLQ + P+ F LW
Sbjct: 68 VDIQMYIEGMSSFHAQSMDFQVDIYFQEKWVDHRLQ-----HNNTKRILVKDPKLFGLLW 122
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
HPD YF N++ ++T V +Y N TV Y R+ + C + YP+D Q+C +
Sbjct: 123 HPDLYFANARTASFHDVTQPNFLVWIYPNGTVWYDCRISLTVLCMQDLARYPLDSQNCGL 182
Query: 133 YIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVV 191
I S++Y +++ RW+ V +N +++ H+ + + Y G +S V
Sbjct: 183 RILSYAYDEEQLIIRWNGGNPVEVNRGIRMPDMHLKHIKFYTKRDKYAT---GIWSSAVA 239
Query: 192 YFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRA 251
F +R+I HH+IQ++ P+SL+V++SWFSFWLD++A+PGR + R
Sbjct: 240 EFHVDREITHHIIQSYIPTSLIVIISWFSFWLDVEAVPGRVSLSITTLLTLATQSSAARM 299
Query: 252 DIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+P + VKA+D+WM CM FVF+A+ EF VV
Sbjct: 300 ALPQASDVKAIDVWMGTCMAFVFSAMIEFTVV 331
>UniRef50_A7SNP9 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 469
Score = 184 bits (448), Expect = 4e-45
Identities = 123/413 (29%), Positives = 195/413 (47%), Gaps = 26/413 (6%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEG-DD 59
+RP G PV+V +V+ ++SINV+DM F +D+F+RQ W ++RL + G +
Sbjct: 66 LRPQYNDG-PVLVTTGFWVLSIDSINVQDMAFGMDIFLRQNWVDNRL-------DHGLNQ 117
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++L N+W PD YF N+K E+T K +T+ V Y+ R+ +C M+
Sbjct: 118 TLSLSNAVMSNIWLPDSYFKNAKQANFHEVTSKNLMITIGPKGKVHYNTRVTLKASCSMD 177
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINP-ELKLLQYHIGQPLRLEET 175
+LYP DIQ CP+ +ES+ YS + + ++W + G++ P ++KLL L L
Sbjct: 178 LRLYPFDIQHCPLIMESYGYSVEHIMYKWEKGEGDGMSFVPRDVKLLPQFNLTKLELSSR 237
Query: 176 NG-YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXX 234
N Y+I GN+S ++ F FER ++I + PS+L+V++SW SF L D P R
Sbjct: 238 NTQYVI---GNWSGVMATFTFERTYSFYVIHIYGPSALIVLISWISFLLPRDQSPARVTL 294
Query: 235 XXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNK 294
T +P V YVKA+D ++ C +FVFA+L E+ ++ VL + M +
Sbjct: 295 GVTSVLTEVTILTMSNNAMPKVNYVKAVDKYLIACFLFVFASLMEYSLILVLANR-TMRR 353
Query: 295 NKAQESMPRIIPVRLNGDKGSCGTIAAWEGSGVRCRKVDIXXXXXXXXXXXXXXXXXXXX 354
K + + R+ + N + +RC
Sbjct: 354 EKQKRAAKRLAMEKENCSEHDPENSKLLLSPNIRC-----ACHRRSPSSSLRNANGNAHQ 408
Query: 355 XXXXXGVERRQSILQVAWLDADTGQERVLWREIDKLSRVVFPALFLLFVTMYW 407
V R S+L V+ D E +L +D+ SR +FP F F YW
Sbjct: 409 PNFALNVTHRDSLL-VSIRDILYRDETIL--AVDEYSRKLFPLAFFAFNVYYW 458
>UniRef50_A7SFG6 Cluster: Predicted protein; n=4; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 424
Score = 184 bits (448), Expect = 4e-45
Identities = 102/332 (30%), Positives = 178/332 (53%), Gaps = 19/332 (5%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V +V+ +++INV DMD+R+D F+RQ W + RL+ DD + L
Sbjct: 27 GDPVTVTVGFWVLSIDAINVIDMDYRMDFFLRQLWRDPRLK------HRFDDTLALSNTM 80
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D +W PD YF+NSK+++ +T +++ + V Y++R+ +C M +++P D+
Sbjct: 81 LDKIWVPDTYFVNSKMSKFHSVTTINKMLSISPDGLVHYNSRVTVKASCAMNLRMFPKDV 140
Query: 128 QSCPIYIESFSYSNQKVRFRW---SEAGVTINPELK-LLQYHIGQPLRLEETNGYMIDKD 183
Q+C I IES+ YS V+++W S+ G+ +N +++ + QY++ + + + +
Sbjct: 141 QNCNIDIESYGYSADNVQYQWENRSDNGIAVNKKIRDMPQYNLSD---INVSRHFTMYVA 197
Query: 184 GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXX 243
GN+S L FRF R+ G+ +I +AP +L+V+LSW SF + ++ R
Sbjct: 198 GNWSGLTATFRFRRRSGYFIIHIYAPCALIVILSWISFCIPPESTAARIALGITSVLTIT 257
Query: 244 XXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDK----QYQMN-KNKAQ 298
L +P V+YVKA+D ++ GC +FVFA L E+ V +D +Y+ + N +
Sbjct: 258 TILNMLNNSMPKVSYVKAVDWYLIGCFLFVFAVLLEYTFVLYIDNEEVTEYKKDLVNYSS 317
Query: 299 ESMPRIIPVR-LNGDKGSCGTIAAWEGSGVRC 329
ES+ P +NG + + A + G +C
Sbjct: 318 ESVKHRSPAHAMNGSIPNGYSPAVFSEHGKKC 349
>UniRef50_P25123 Cluster: Gamma-aminobutyric acid receptor subunit
beta precursor (GABA(A) receptor subunit beta); n=45;
Pancrustacea|Rep: Gamma-aminobutyric acid receptor
subunit beta precursor (GABA(A) receptor subunit beta) -
Drosophila melanogaster (Fruit fly)
Length = 606
Score = 184 bits (448), Expect = 4e-45
Identities = 96/296 (32%), Positives = 162/296 (54%), Gaps = 10/296 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G PV V ++YV+ ++S++ MDF +D + RQ W++ RL + G + +++
Sbjct: 76 PNYGGPPVEVGVTMYVLSISSVSEVLMDFTLDFYFRQFWTDPRLAYRK---RPGVETLSV 132
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
EF N+W PD +F+N K + T + ++ + ++ S R+ +C M Q +
Sbjct: 133 GSEFIKNIWVPDTFFVNEKQSYFHIATTSNEFIRVHHSGSITRSIRLTITASCPMNLQYF 192
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSE--AGVTINPELKLLQYHI-GQPLRLEETNGYMI 180
PMD Q C I IESF Y+ + +R+ W + + V ++ E++L Q+ + G R E N
Sbjct: 193 PMDRQLCHIEIESFGYTMRDIRYFWRDGLSSVGMSSEVELPQFRVLGHRQRATEINL--- 249
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
GNYSRL +F R +G++LIQ + PS L+V++SW SFWL+ +A P R
Sbjct: 250 -TTGNYSRLACEIQFVRSMGYYLIQIYIPSGLIVIISWVSFWLNRNATPARVALGVTTVL 308
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
+ A +P ++YVK++D+++ C + VFA+L E+ V + K+ QM K +
Sbjct: 309 TMTTLMSSTNAALPKISYVKSIDVYLGTCFVMVFASLLEYATVGYMAKRIQMRKQR 364
Score = 35.5 bits (78), Expect = 2.6
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+IDK SR+VFP F+ F MYW + L
Sbjct: 565 DIDKYSRIVFPVCFVCFNLMYWIIYL 590
>UniRef50_UPI00015B58ED Cluster: PREDICTED: similar to GABA-gated
ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to GABA-gated ion channel - Nasonia vitripennis
Length = 513
Score = 179 bits (435), Expect = 1e-43
Identities = 98/311 (31%), Positives = 158/311 (50%), Gaps = 11/311 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G P+ VE + + ++I+ +MD+ + M++ Q W + RL F + +TL +F
Sbjct: 72 GDPLFVEMDLTIASFDAISEVNMDYTITMYLNQYWKDERLA-----FSHEKEILTLSGDF 126
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ +W PD +F N K + + ++T + V L + +V Y R +AC M+ YP+D
Sbjct: 127 AEKIWVPDTFFANDKHSFLHDVTERNKLVRLAGDGSVTYGMRFTTTLACMMDLHYYPLDS 186
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYS 187
Q+C + IES+ Y+ V W E V E KL Q+ I + E + G Y
Sbjct: 187 QNCTVEIESYGYTVLDVVMSWKETPVRGVDEAKLPQFTI---IGYETNDRKEKLATGIYQ 243
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
RL + F+ +R IG+ + QT+ PS L+VMLSW SFW++ +A R T
Sbjct: 244 RLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVLTMTTIST 303
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL---DKQYQMNKNKAQESMPRI 304
G+R+ +P ++YVKA+D+++ C +FVFAAL E+ V + + +K K E +
Sbjct: 304 GVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGARAKKKSKKKETEEEKKT 363
Query: 305 IPVRLNGDKGS 315
I G K S
Sbjct: 364 ICSSKTGSKAS 374
>UniRef50_Q2WF65 Cluster: Gaba/glycine receptor family (See gbr)
protein 2, isoform a; n=3; Caenorhabditis|Rep:
Gaba/glycine receptor family (See gbr) protein 2,
isoform a - Caenorhabditis elegans
Length = 546
Score = 179 bits (435), Expect = 1e-43
Identities = 87/290 (30%), Positives = 153/290 (52%), Gaps = 11/290 (3%)
Query: 3 PPAR--KGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
PP + K + +VE ++Y+ ++S + MDF++D++ +Q W + RL E D
Sbjct: 46 PPVQHDKEEVTVVELAMYIEGMSSFRTQTMDFQLDVYFQQFWRDPRLAHNETRRVLVKDK 105
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
L +W PD YF N+++ E E+T V + + ++ Y R+ ++ C +
Sbjct: 106 AVL-----HKMWKPDVYFANARIAEFHEVTQPNFLVWIQPDGSILYDTRISMVVVCTLNL 160
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSE-AGVTINPELKLLQYHIGQPLRLEETNGYM 179
+ +P+D Q C + I S++Y+ +++ +W E +T NP + + HI Y
Sbjct: 161 EKWPLDSQRCHLRILSYAYTTEQLVIKWKEDEPITRNPNIAMSDMHIVDLYPGLCDGNY- 219
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
G +S + F +R+I HH++Q++ P++L+V++SWFSFWLD++A+P R
Sbjct: 220 --STGTWSCVTAEFFVKREITHHVMQSYVPTTLIVVISWFSFWLDVEAVPARVSLAITTL 277
Query: 240 XXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
R +P V+Y+KA+D+WM CMMFVF + EF +V +Q
Sbjct: 278 LTLSTQANAARMALPEVSYMKAIDVWMGACMMFVFGVMIEFTIVNYAQRQ 327
>UniRef50_A7S763 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 278
Score = 177 bits (430), Expect = 6e-43
Identities = 94/277 (33%), Positives = 153/277 (55%), Gaps = 10/277 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PVIV ++V+D+ I+ DM+FRV F RQ W ++RL + + + L
Sbjct: 3 GDPVIVYTDMFVLDIGDISEADMEFRVMFFYRQYWQDTRLAYDYTGYNK---RLALNARM 59
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D +W PD YF+N K +LT + V ++ + V +S R+ +C M+ YPMD
Sbjct: 60 VDYMWIPDIYFVNEKSGIKHDLTKQNEVVRVWPDGRVFHSIRLSMTASCPMKLHSYPMDK 119
Query: 128 QSCPIYIESFSYSNQKVRFRWSE----AGVTINPELKLLQYHIGQPLRLEETNGYMIDKD 183
Q+C + ESFSY + ++ F+W++ V ++ EL++ Q+ + + + T+ +
Sbjct: 120 QTCKLSFESFSYPSTELIFKWNKNRGNKEVQVSDELQIPQFILTE---YKTTSEFANFTT 176
Query: 184 GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXX 243
G+YSRL V FRFER IG LIQT+ P+ L+VMLSW +FW++ + P R
Sbjct: 177 GSYSRLTVLFRFERSIGFFLIQTYIPAYLIVMLSWIAFWINHTSTPARIGLGITTVLTMT 236
Query: 244 XXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEF 280
RA +P V+YVK+++ ++ C ++VF +L E+
Sbjct: 237 TLTNSARASLPKVSYVKSIEWFLIMCFLYVFMSLVEY 273
>UniRef50_O00591 Cluster: Gamma-aminobutyric acid receptor subunit
pi precursor (GABA(A) receptor subunit pi); n=19;
Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit pi precursor (GABA(A) receptor subunit pi) -
Homo sapiens (Human)
Length = 440
Score = 177 bits (430), Expect = 6e-43
Identities = 91/292 (31%), Positives = 152/292 (52%), Gaps = 12/292 (4%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G+PV + ++ + ++SI+ +MD+ +++RQ W + RL +FE G+ TL
Sbjct: 58 GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRL-----VFE-GNKSFTLDARL 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD Y + SK + + E+T + L+ N TV Y+ R+ +AC M+ YPMD
Sbjct: 112 VEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDT 171
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + +ES+ Y V F W ++ L+L QY I + L + + GN
Sbjct: 172 QTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQ---QETGN 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y+RLV+ F R + + +++T+ PS+ +V+LSW SFW+ LD++P R
Sbjct: 229 YTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTL 288
Query: 246 FTGLRADIPPV-AYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
G R +P ++KA+D+++ C FVF AL E+ V Q K++
Sbjct: 289 MIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
>UniRef50_A7SLK4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 319
Score = 175 bits (427), Expect = 1e-42
Identities = 89/285 (31%), Positives = 159/285 (55%), Gaps = 11/285 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG+PV+V +YV ++ ++ +MDF +D+++RQ W + RLQ + +TL
Sbjct: 39 PGSKGEPVVVYVDMYVSNIWAMQEMNMDFTIDIYLRQYWRDERLQFET---QTPGAMLTL 95
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+ +W P YFL +K ++T + + + ++ YS R+ +C+++ + +
Sbjct: 96 SSDINKQIWVPSTYFLATKKAYFHDVTTDNYLLQVKPDGSLFYSIRLTITTSCRLDLRDF 155
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSE-----AGVTINPELKLLQYHIGQPLRLEETNGY 178
P D QSC + +ES+ Y + V + W+E + + I+ +L+L Q+ + R + N Y
Sbjct: 156 PHDTQSCSLSLESYGYQSTDVLYVWNERLDNTSAIYIHDDLELPQFEVLGVSRSAKMNKY 215
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
I GN+S LV FR +R+IG+ LI T+ PS+++V++SW SFW+D + P R
Sbjct: 216 NI---GNHSSLVANFRMKRRIGYFLIDTYIPSTIIVIISWISFWIDPETAPARVALGITT 272
Query: 239 XXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ RA++P V+YVKA+D ++ C++FVF ++ E+ V
Sbjct: 273 VLTMTTLISSARANLPKVSYVKAIDWYLLLCLIFVFGSILEYTCV 317
>UniRef50_P18505 Cluster: Gamma-aminobutyric acid receptor subunit
beta-1 precursor (GABA(A) receptor subunit beta-1);
n=104; Euteleostomi|Rep: Gamma-aminobutyric acid
receptor subunit beta-1 precursor (GABA(A) receptor
subunit beta-1) - Homo sapiens (Human)
Length = 474
Score = 175 bits (425), Expect = 2e-42
Identities = 93/281 (33%), Positives = 150/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V I V ++ ++ +MD+ + M+ +Q+W + RL + ++TL
Sbjct: 58 GPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLS-----YSGIPLNLTLDNRV 112
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 113 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 172
Query: 128 QSCPIYIESFSYSNQKVRFRWS--EAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W+ E VT +++L Q+ I + + + G
Sbjct: 173 QNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTT---GA 229
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + FR +R IG+ ++QT+ PS+L+ +LSW SFW++ DA R
Sbjct: 230 YPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTI 289
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ V +
Sbjct: 290 STHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYI 330
>UniRef50_P47870-2 Cluster: Isoform Long of P47870 ; n=22;
Eumetazoa|Rep: Isoform Long of P47870 - Homo sapiens
(Human)
Length = 512
Score = 173 bits (422), Expect = 5e-42
Identities = 90/281 (32%), Positives = 151/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V +I + ++ ++ +MD+ + M+ +Q W + RL + ++TL
Sbjct: 57 GPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLS-----YNVIPLNLTLDNRV 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 112 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 171
Query: 128 QSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W + VT +++L Q+ I + + ++ G+
Sbjct: 172 QNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKK---VVFSTGS 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + F+ +R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 229 YPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTI 288
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ +V +
Sbjct: 289 NTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
>UniRef50_Q4S0E0 Cluster: Chromosome 2 SCAF14781, whole genome
shotgun sequence; n=5; Euteleostomi|Rep: Chromosome 2
SCAF14781, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 525
Score = 170 bits (414), Expect = 5e-41
Identities = 106/318 (33%), Positives = 162/318 (50%), Gaps = 40/318 (12%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G PV V +I++ SI MD+RV++F+RQ W++ RL + D + L
Sbjct: 108 PQPAGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSK----YPDPSLDL 163
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K ++T + +++N V YS R+ I++C M+ + +
Sbjct: 164 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRIFKNGNVLYSIRLTLILSCPMDLKNF 223
Query: 124 PMDIQ-------SCPIYIESFSYSNQKVR----------------------FRWSEAG-V 153
PMD+Q SC SF +Q+ R F W E G V
Sbjct: 224 PMDVQTCTMQLESCECCFLSFPRLSQRPRALILTHLSRSSLPVGYTMNDLIFEWLENGAV 283
Query: 154 TINPELKLLQYHIGQPLRLEETNGYMID--KDGNYSRLVVYFRFERQIGHHLIQTFAPSS 211
++ L L Q+ +R E+ GY G ++ + V F ERQ+G++LIQ + PS
Sbjct: 284 QVSDGLTLPQFI----MRDEKELGYCTKHYNTGKFTCIEVKFHLERQMGYYLIQMYIPSL 339
Query: 212 LVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMM 271
L+V+LSW SFW+++DA P R +G RA +P V+YVKA+D+WMA C++
Sbjct: 340 LIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLL 399
Query: 272 FVFAALGEFVVVKVLDKQ 289
FVFAAL E+ V + +Q
Sbjct: 400 FVFAALLEYAGVNFVSRQ 417
>UniRef50_Q9UN88 Cluster: Gamma-aminobutyric acid receptor subunit
theta precursor (GABA(A) receptor subunit theta); n=18;
Tetrapoda|Rep: Gamma-aminobutyric acid receptor subunit
theta precursor (GABA(A) receptor subunit theta) - Homo
sapiens (Human)
Length = 632
Score = 170 bits (413), Expect = 7e-41
Identities = 92/304 (30%), Positives = 157/304 (51%), Gaps = 12/304 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V SIYV + I+ +MD+ + MF QTW +SRL E ++TL
Sbjct: 80 GAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETTL-----NLTLDYRM 134
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD YFLNSK + ++T + L+ + TVRY R+ AC ++ +PMD
Sbjct: 135 HEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDK 194
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQY-HIGQPLRLEETNGYMIDKDG 184
Q+C + +ES+ Y+ + + W + G I+ EL + Q+ +G+ + +E Y G
Sbjct: 195 QACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYT----G 250
Query: 185 NYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXX 244
+Y RL++ F+ +R++ +L+Q + P+ L + SW SFW++ D+ R
Sbjct: 251 SYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTT 310
Query: 245 XFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRI 304
+ LR +P ++ +KA+D+++ C+ FVF +L E+V + L + + PR
Sbjct: 311 IDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRPRR 370
Query: 305 IPVR 308
+ R
Sbjct: 371 VIAR 374
>UniRef50_Q22741 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 494
Score = 169 bits (412), Expect = 9e-41
Identities = 87/303 (28%), Positives = 152/303 (50%), Gaps = 13/303 (4%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVT 62
P G P V S+++ ++S + + MD+ +D++ ++ W + RL +
Sbjct: 50 PTQYDGVPTNVTLSMFIEGMSSFSAQTMDYHLDVYFQEEWYDHRLA-----HNASAPILV 104
Query: 63 LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQL 122
F +WHPD YF N++ ++T V +Y N V Y AR+ + +C M+
Sbjct: 105 RDLTVFKMMWHPDVYFANARSAAFQDITDDNFLVWVYPNGRVWYDARISIVSSCNMDLWK 164
Query: 123 YPMDIQSCPIYIESFSYSNQKVRFRWSEA----GVTINPELKLLQYHIGQPLRLEETNGY 178
YP+D Q C + I S++Y +R WSE + NP++ + + + +R NG
Sbjct: 165 YPLDSQECALRILSYAYPMTVLRLLWSEKEDVPAIDRNPDITMPDMSL-KHIRTGYCNGT 223
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
G +S + F ER++ HH++QT+ P++L+V++SWF+FWL++D+ P R
Sbjct: 224 YAT--GEWSCMTAIFYVEREMMHHVMQTYVPTALIVVISWFNFWLEIDSAPARVSLSITT 281
Query: 239 XXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQ 298
++ +P V+Y+KA+D+WM CM FVF + EF + K +M + Q
Sbjct: 282 LLTISTQANAVKLALPEVSYMKAIDVWMGSCMAFVFGVMIEFTICHYA-KNLEMLRGDGQ 340
Query: 299 ESM 301
S+
Sbjct: 341 PSL 343
>UniRef50_Q08832 Cluster: Gamma-aminobutyric acid receptor subunit
beta-like precursor (GABA(A) receptor); n=11;
Protostomia|Rep: Gamma-aminobutyric acid receptor
subunit beta-like precursor (GABA(A) receptor) -
Drosophila melanogaster (Fruit fly)
Length = 496
Score = 169 bits (411), Expect = 1e-40
Identities = 94/304 (30%), Positives = 157/304 (51%), Gaps = 12/304 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRL------QLPEDIFEEG-DDH 60
G+P+ V + + ++I+ +MD+ + M++ Q W + RL Q +D ++G D
Sbjct: 61 GEPLHVGMDLTIASFDAISEVNMDYTITMYLNQYWRDERLAFNIFGQYFDDENDDGISDV 120
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+TL +F + +W PD +F N K + + ++T + V L + V Y R +AC M+
Sbjct: 121 LTLSGDFAEKIWVPDTFFANDKNSFLHDVTERNKLVRLGGDGAVTYGMRFTTTLACMMDL 180
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
YP+D Q+C + IES+ Y+ V W V + +L Q+ I + E +
Sbjct: 181 HYYPLDSQNCTVEIESYGYTVSDVVMYWKPTPVRGVEDAELPQFTI---IGYETNDRKER 237
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G Y RL + F+ +R IG+ + QT+ PS L+VMLSW SFW++ +A R
Sbjct: 238 LATGVYQRLSLSFKLQRNIGYFVFQTYLPSILIVMLSWVSFWINHEATSARVALGITTVL 297
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL--DKQYQMNKNKAQ 298
TG+R+ +P ++YVKA+D+++ C +FVFAAL E+ V K+ + K +
Sbjct: 298 TMTTISTGVRSSLPRISYVKAIDIYLVMCFVFVFAALLEYAAVNYTYWGKRAKKKIKKVK 357
Query: 299 ESMP 302
E P
Sbjct: 358 ECCP 361
>UniRef50_Q8MTJ9 Cluster: Ionotropic GABA receptor beta subunit 1b;
n=8; Pancrustacea|Rep: Ionotropic GABA receptor beta
subunit 1b - Homarus americanus (American lobster)
Length = 521
Score = 169 bits (410), Expect = 2e-40
Identities = 88/268 (32%), Positives = 134/268 (50%), Gaps = 8/268 (2%)
Query: 31 DFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELT 90
DF +D + RQ W++ RL P G D +T+ E+ +W PD +F N K + T
Sbjct: 128 DFTLDFYFRQHWTDPRLSFPG---RGGLDELTVGSEYLQKIWVPDTFFANEKKSYFHTAT 184
Query: 91 HKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRW-- 148
+ + V S R+ +C M Q +PMD + C I IESF YS +R W
Sbjct: 185 TSNEMLRITNQGKVLRSIRLTITASCPMNLQYFPMDRELCIIEIESFGYSMDHIRLSWHA 244
Query: 149 SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFA 208
+ V I ++ L Q+ + L GNYSRL+ F R +G++LIQ +
Sbjct: 245 GDRSVVIESDVSLPQFRV---LGYNRKTIISSTSTGNYSRLLCEIMFVRSMGYYLIQIYI 301
Query: 209 PSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAG 268
PSSL+V++SW SFWL+ A P R + A +P ++YVK++D+++
Sbjct: 302 PSSLIVVISWVSFWLNRSATPARVSLGVTTVLTMTTLMSSTNAALPKISYVKSIDVYLGT 361
Query: 269 CMMFVFAALGEFVVVKVLDKQYQMNKNK 296
C + VFA+L E+ V + K+ QM KN+
Sbjct: 362 CFVMVFASLLEYAAVGYMGKRIQMRKNR 389
Score = 35.5 bits (78), Expect = 2.6
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+IDK SR+VFP F+ F MYW + L
Sbjct: 479 DIDKYSRIVFPVCFVCFNLMYWIIYL 504
>UniRef50_Q08861 Cluster: Gamma-aminobutyric acid-grated
chloride-ion channel/receptor, zeta subunit precursor;
n=1; Lymnaea stagnalis|Rep: Gamma-aminobutyric
acid-grated chloride-ion channel/receptor, zeta subunit
precursor - Lymnaea stagnalis (Great pond snail)
Length = 437
Score = 167 bits (406), Expect = 5e-40
Identities = 93/303 (30%), Positives = 155/303 (51%), Gaps = 17/303 (5%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRL--QLPEDIFEEGD-D 59
P K +P ++ +YV ++++N MDF V + + W+++R+ ++F +
Sbjct: 50 PSYDKLEPARIQVLLYVSSIDAVNEASMDFTVGILLHLRWTDTRIYHDKAHNLFLQSKLQ 109
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ E +W PD +F N K ++ + + LY+ T+ Y +R+ ++C M+
Sbjct: 110 SLDFDSENIKKVWVPDIFFPNEKKGSFHDIMTQNQMMRLYQGGTILYISRLSMTLSCPMD 169
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEA----GVTINP---------ELKLLQYHI 166
YP D Q+C I I SF YS+Q + W +T+NP E+ L Q+ +
Sbjct: 170 LINYPFDKQTCHILIMSFGYSDQDLVLDWMNLTTADDLTMNPDGKAIVVDSEVLLPQFEV 229
Query: 167 GQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
+ Y K GN+S + F R IG +++Q + PS L+VMLSW SFWL ++
Sbjct: 230 KSVIPSFCNRRYH-QKAGNHSCIQAEFHLARNIGFYIVQMYIPSMLIVMLSWISFWLTVN 288
Query: 227 AIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
++PGR + + A +P V+Y KA+D+WM+ C++FVFAAL EF VV VL
Sbjct: 289 SVPGRVSLGLLTVLTMTTQSSSVNAALPRVSYTKAIDVWMSTCLVFVFAALLEFAVVNVL 348
Query: 287 DKQ 289
++
Sbjct: 349 SRK 351
>UniRef50_O18276 Cluster: Gamma-aminobutyric acid receptor subunit
beta precursor (GABA(A) receptor subunit beta); n=3;
Rhabditida|Rep: Gamma-aminobutyric acid receptor subunit
beta precursor (GABA(A) receptor subunit beta) -
Caenorhabditis elegans
Length = 550
Score = 167 bits (405), Expect = 6e-40
Identities = 82/280 (29%), Positives = 146/280 (52%), Gaps = 5/280 (1%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G +++ I + +SI+ DMD+ + M++ Q W++ RL+ +I D +TL
Sbjct: 71 PGFGGDALLLTMDIIIASFDSISEVDMDYTLTMYLHQYWTDERLRWSNEI---PIDEMTL 127
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
EF N+W PD + N K + + E+T + + + + V Y R+ + ++C M + +
Sbjct: 128 SGEFSQNIWVPDTFLANDKHSYLHEVTERNKMLRINVDGKVAYGMRLTSTLSCSMNLRNF 187
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD 183
P+D Q+C + IES+ Y+ +V +W+ E + E++ +
Sbjct: 188 PLDSQNCTVEIESYGYTTSEVLMKWNYPLAVHGVEQADVPQFTITGFHTEDS--IVSTAT 245
Query: 184 GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXX 243
G+Y RL + F+ R +G+ + QT+ P L+VMLSW SFW++ +A R
Sbjct: 246 GSYQRLSLVFQLRRSVGYFIFQTYLPCVLIVMLSWVSFWINHEATSARVALGITTVLTMT 305
Query: 244 XXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
TG+R +P ++YVK++D+++ C +FVFAAL E+ V
Sbjct: 306 TISTGVRQSLPRISYVKSIDIYLVMCFVFVFAALLEYAAV 345
>UniRef50_A7RS31 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 303
Score = 164 bits (398), Expect = 4e-39
Identities = 87/282 (30%), Positives = 144/282 (51%), Gaps = 4/282 (1%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
PV+V + +V ++ DM+F +M+ RQ W + RL + +TL + D
Sbjct: 1 PVLVTTELNLVSISQFREADMEFTAEMYFRQAWHDPRLAFGVTMGNSTVPVITLYGDLSD 60
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
+LW PD YF N +I ELT K + +Y + V S R+ +C M+F+ +PMD Q+
Sbjct: 61 SLWQPDTYFENEVQGKIHELTIKNKYMRVYSDGRVMTSLRVTLSCSCAMDFRKFPMDKQN 120
Query: 130 CPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRL 189
C I S+ Y+ + ++W++ VT + ++ Q+ + + T Y+ G++S L
Sbjct: 121 CGISFASYGYTTADIVYQWADERVTWAHDQEIAQFVLEKIETENLTRRYI---TGDFSAL 177
Query: 190 VVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGL 249
+ R R++GH+L + + P+ L+VMLSW SF+LD + P R G+
Sbjct: 178 GIRLRLNRRLGHYLTRVYVPAVLIVMLSWLSFYLDRHSAPARVSLGITTVLTMTTLLIGI 237
Query: 250 -RADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY 290
+ +P V+YVKALD ++ VF A E+ V+ DK Y
Sbjct: 238 GQGSLPVVSYVKALDWYLFVSYCMVFGAFAEYAVINHRDKSY 279
>UniRef50_Q99928 Cluster: Gamma-aminobutyric acid receptor subunit
gamma-3 precursor (GABA(A) receptor subunit gamma-3);
n=106; Euteleostomi|Rep: Gamma-aminobutyric acid
receptor subunit gamma-3 precursor (GABA(A) receptor
subunit gamma-3) - Homo sapiens (Human)
Length = 467
Score = 164 bits (398), Expect = 4e-39
Identities = 82/275 (29%), Positives = 138/275 (50%), Gaps = 6/275 (2%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +++ IYV + ++ +M++++D+F QTW++SRL+ F +TL
Sbjct: 69 KPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLR-----FNSTMKILTLNSNMV 123
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD F NSK E +T + ++ + + Y+ R+ CQ++ +PMD
Sbjct: 124 GLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEH 183
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
SCP+ S+ Y +++ +RW + V + Y + L T + G+Y
Sbjct: 184 SCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDF-MGLRNTTEIVTTSAGDYVV 242
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ +YF R++G+ IQT+ P L V+LSW SFW+ DA P R T
Sbjct: 243 MTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTI 302
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
R +P V+YV A+DL++ C +FVFAAL E+ +
Sbjct: 303 ARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
>UniRef50_O14764 Cluster: Gamma-aminobutyric acid receptor subunit
delta precursor (GABA(A) receptor subunit delta); n=27;
Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit delta precursor (GABA(A) receptor subunit delta)
- Homo sapiens (Human)
Length = 452
Score = 163 bits (396), Expect = 8e-39
Identities = 89/302 (29%), Positives = 153/302 (50%), Gaps = 9/302 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G PV V ++ V ++ I+ +M++ + +F+ Q+W +SRL + ++ + L
Sbjct: 57 PGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLS-----YNHTNETLGL 111
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
F D LW PD + +N+K ++T + + L + + YS R+ + +AC M+ Y
Sbjct: 112 DSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKY 171
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMID 181
PMD Q C + +ES+ YS++ + + WSE+ I+ +L+L Q+ I E +
Sbjct: 172 PMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFK-- 229
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
G + RL ++F R G ++IQ++ PS L+V +SW SFW+ A+P R
Sbjct: 230 SAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLT 289
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESM 301
R+ +P + +KALD++ C +FVFAAL E+ + K K + S
Sbjct: 290 MTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSR 349
Query: 302 PR 303
PR
Sbjct: 350 PR 351
>UniRef50_UPI00015B5C4C Cluster: PREDICTED: similar to GABA-gated
ion channel; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to GABA-gated ion channel - Nasonia vitripennis
Length = 442
Score = 161 bits (392), Expect = 2e-38
Identities = 93/283 (32%), Positives = 142/283 (50%), Gaps = 11/283 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G P +VE I V + I+ DM + +D + RQ+W + RL F+ G + + L
Sbjct: 71 GPPAVVEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDRRLA-----FQSGKETLALSISM 125
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+W PD YF N K + + +T V LY++ V YS+R+ AC M + +PMD
Sbjct: 126 LARIWKPDTYFYNGKQSYLHTITSPNKFVRLYQDGRVLYSSRLTIKAACPMNLEDFPMDT 185
Query: 128 QSCPIYIESFSYSNQKVRFRWSEA-GVTINPELKLLQYH-IGQPLRLEETNGYMIDKDGN 185
Q CP+ S+ Y+ + V ++W+ A V I ++KL Q+ +G P T+ + K
Sbjct: 186 QRCPLKFGSYGYTTRDVIYKWNSARQVAIAHDMKLSQFDLVGNP-TANATDSTLSQK--- 241
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
YS L+V F +R +G+ LIQ + P L+V+LSW SFWL+ +A R
Sbjct: 242 YSMLLVSFHLKRHMGNFLIQVYGPCVLLVVLSWVSFWLNREATADRVSLGITTVLTMTFL 301
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDK 288
R D+P V Y ALD ++ F+FA + +F VV K
Sbjct: 302 GLEARTDLPKVPYPTALDFFVFLSFGFIFATIIQFAVVHYFTK 344
>UniRef50_Q0GQR6 Cluster: GABA-gated ion channel; n=2; Apis
mellifera|Rep: GABA-gated ion channel - Apis mellifera
(Honeybee)
Length = 463
Score = 161 bits (391), Expect = 3e-38
Identities = 91/283 (32%), Positives = 138/283 (48%), Gaps = 9/283 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G P VE I V + I+ DM + +D + RQ+W + RL F+ G + + L
Sbjct: 27 GPPATVEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDRRLA-----FQGGKETLALSISM 81
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+W PD YF N K + + +T V LY++ V YS+R+ C M + +PMD
Sbjct: 82 LARIWKPDTYFYNGKHSYLHTITSPNKFVRLYQDGRVLYSSRLTIKAGCPMNLENFPMDT 141
Query: 128 QSCPIYIESFSYSNQKVRFRWSEA-GVTINPELKLLQYH-IGQPLRLEETNGYMIDKDGN 185
Q CP+ SF Y+ + V ++W+ A V I ++KL Q+ + P + +
Sbjct: 142 QRCPLQFGSFGYTKRDVIYKWNSARQVAIAEDMKLSQFDLVANPTANYSASTTL--SHAE 199
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
YS L+VYF +R +G+ LIQ + P L+V+LSW SFWL+ +A R
Sbjct: 200 YSMLLVYFHLQRHMGNFLIQVYGPCVLLVVLSWVSFWLNREATADRVSLGITTVLTMTFL 259
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDK 288
R D+P V Y ALD ++ F+FA + +F VV K
Sbjct: 260 GLEARTDLPKVPYPTALDFFVFLSFAFIFATIIQFAVVHYFTK 302
>UniRef50_O17547 Cluster: GluClalpha2A protein; n=66;
Chromadorea|Rep: GluClalpha2A protein - Caenorhabditis
elegans
Length = 657
Score = 161 bits (391), Expect = 3e-38
Identities = 89/317 (28%), Positives = 154/317 (48%), Gaps = 13/317 (4%)
Query: 1 MRPPARKGQ----PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEE 56
+RPP G PV+V ++ + ++ I+ +M++ V + R++W + RL +
Sbjct: 267 VRPPGEDGTIHGGPVVVSVNMLLRSISKIDNVNMEYSVQLTFRESWVDKRLSFGVKGDAQ 326
Query: 57 GDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIAC 116
D + + +W PD +F N + + ++++ T+ YS R+ +++C
Sbjct: 327 PDFLILTAGQ---EIWMPDSFFQNENQAYKHMIDKPNVLIRVHKDGTILYSVRISLVLSC 383
Query: 117 QMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETN 176
M Q YPMD+Q C I + S++Y+ + + + W E +LK +L T+
Sbjct: 384 PMHLQYYPMDVQQCFIDLASYAYTTKDIEYVWKEETPV---QLKAGLSSSLPSFQLTNTS 440
Query: 177 G-YMIDKD--GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXX 233
Y K G+YS L + RQ ++L+Q + PS ++V++SW SFW+D A+P R
Sbjct: 441 TTYCTSKTNTGSYSCLRTIIQLRRQFSYYLLQLYIPSCMLVIVSWVSFWIDRTAVPARVT 500
Query: 234 XXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMN 293
+G+ A +PPVAY+KA+D+W+ CM F+F AL EF V + + N
Sbjct: 501 LGVTTLLTMTTQSSGINAKLPPVAYIKAIDVWIGACMTFIFCALLEFAWVTYIANKQDAN 560
Query: 294 KNKAQESMPRIIPVRLN 310
K E +P N
Sbjct: 561 KRARTEREKAELPFLQN 577
>UniRef50_O17402 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 563
Score = 160 bits (389), Expect = 5e-38
Identities = 87/290 (30%), Positives = 141/290 (48%), Gaps = 14/290 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
M P +G+ V ++Y+ ++S + MDF VDM++ W + RL H
Sbjct: 138 MAPGQSQGKRTDVHVAVYIESMSSFKAQSMDFEVDMYLAMGWFDRRLA-------HNCTH 190
Query: 61 VTLPPE--FFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQM 118
L D +W+PD YF+NSK + E+T V +Y + + + R+ ++C M
Sbjct: 191 PILVTSKLIADRIWYPDLYFVNSKYAYLQEVTTPNLMVIVYPDGLIFKTMRLDVTLSCMM 250
Query: 119 EFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAG----VTINPELKLLQYHIGQPLRLEE 174
+ +L+P+D Q CP+ I+SF+Y Q V W + + NP++KL I ++
Sbjct: 251 DLKLFPLDYQECPLTIQSFAYIEQIVNLTWRDDPPNFPIGFNPDIKLNDMQITNKRFVKC 310
Query: 175 TNGY-MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXX 233
Y M + +S + Y +R + H+IQT+ P+ ++V +SW SFWLD A P R
Sbjct: 311 AGPYPMFRGEAAWSCIQGYIVMKRLVLFHIIQTYIPTGMLVSISWMSFWLDPRASPARIS 370
Query: 234 XXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
G R D+P V+Y+KALD+W+ +F L E+ V
Sbjct: 371 LTITSLLTLTTMSNGARQDLPQVSYIKALDIWLTFSQALIFLVLLEYSFV 420
>UniRef50_Q21420 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 457
Score = 160 bits (388), Expect = 7e-38
Identities = 92/298 (30%), Positives = 153/298 (51%), Gaps = 10/298 (3%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
R P G PV VEF +V + SIN DF +D++I + W + L+ D ++
Sbjct: 71 RIPNENGVPVQVEF--WVQAITSINEITNDFEMDIYINEMWLDPALKF--DHLNPCKQNL 126
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
++ + + LW P+ F+NSK EI + K + +Y N TV + R++ C + +
Sbjct: 127 SVSHQVLEQLWTPNSCFVNSKFAEIHDSPFKNVFLMIYPNGTVWVNYRVNVKGPCDLSLE 186
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAG---VTINPELKLLQYHIGQPLRLEETNGY 178
L+P+DIQ C + ESF+Y+NQ+VR RW+E V++ +++L + + +++E T
Sbjct: 187 LFPLDIQECHLIYESFNYNNQEVRMRWNEKSAEPVSVTNKIRLPDFEL---IKIESTRIS 243
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
G + L V FER+ + +Q + P+ L + +SW SF L A+P R
Sbjct: 244 APYPAGMWDELHVKLVFERRYIWYFMQAYLPTYLTIFISWISFSLGTKAMPARTMLGVNA 303
Query: 239 XXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
F + ++P V+YVKA+D+WM M F+F +L E +V K + +K K
Sbjct: 304 LLAMIFQFGNIMRNLPRVSYVKAIDVWMLVSMTFIFLSLLELAIVGYKTKNEEGSKKK 361
>UniRef50_A7LPG1 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 564
Score = 159 bits (385), Expect = 2e-37
Identities = 90/291 (30%), Positives = 140/291 (48%), Gaps = 15/291 (5%)
Query: 2 RPP-ARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
RPP A P+ V+ +Y+ + + +M F VD+++ +W + RL D+
Sbjct: 41 RPPTANASVPLGVKLGMYLESLGNFRSSEMSFDVDLYVYMSWQDPRLA------HNFSDY 94
Query: 61 VTLP-PEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
V + E +W PD YF N++ E+T ++ + + TV YS R +AC +
Sbjct: 95 VLINNDEIRKQIWLPDLYFANARQASFQEVTVPNFNLFVAPDGTVAYSCRCTLTVACSLN 154
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNGY 178
+ YPMD Q C I + S++Y ++V W + V N E+ L ++ I Y
Sbjct: 155 LRYYPMDQQLCSIRVLSYAYIAKQVNVTWFDKNPVRFNEEIGLPEFQIEHVSNAYCNGSY 214
Query: 179 MID------KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRX 232
K ++S L R IG++L+Q++ P+ L+VM+SW SFW+D A+P R
Sbjct: 215 QYALTENSYKSDDFSCLSGNLFLSRSIGYNLVQSYIPTGLIVMISWVSFWIDRRAVPARV 274
Query: 233 XXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
GLR +P V+Y KA+DLW CM FVF AL EF +
Sbjct: 275 TLSFTTLVSLTTLGNGLRFGLPQVSYAKAIDLWYGACMFFVFCALLEFATI 325
>UniRef50_Q94900 Cluster: Glutamate-gated chloride channel
precursor; n=21; Pancrustacea|Rep: Glutamate-gated
chloride channel precursor - Drosophila melanogaster
(Fruit fly)
Length = 456
Score = 159 bits (385), Expect = 2e-37
Identities = 91/306 (29%), Positives = 153/306 (50%), Gaps = 10/306 (3%)
Query: 1 MRPPARKGQ--PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGD 58
+RP G P IV +++V + +I+ M++ V + R+ W++ RL+ D +
Sbjct: 50 IRPSGINGTDGPAIVRINLFVRSIMTISDIKMEYSVQLTFREQWTDERLKF--DDIQGRL 107
Query: 59 DHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQM 118
++TL + +W PD +F N K + + ++ N +V YS R+ +AC M
Sbjct: 108 KYLTLTEA--NRVWMPDLFFSNEKEGHFHNIIMPNVYIRIFPNGSVLYSIRISLTLACPM 165
Query: 119 EFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNG 177
+LYP+D Q C + + S+ ++ + F W E V + L L ++ + + L + N
Sbjct: 166 NLKLYPLDRQICSLRMASYGWTTNDLVFLWKEGDPVQVVKNLHLPRFTLEKFLT-DYCNS 224
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
G YS L V F+R+ ++LIQ + P ++V++SW SFWLD A+P R
Sbjct: 225 KT--NTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQGAVPARVSLGVT 282
Query: 238 XXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKA 297
+G+ A +PPV+Y KA+D+W C+ FVF AL EF +V + N
Sbjct: 283 TLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSGSNKANMH 342
Query: 298 QESMPR 303
+ESM +
Sbjct: 343 KESMKK 348
>UniRef50_Q20828 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 517
Score = 158 bits (383), Expect = 3e-37
Identities = 95/308 (30%), Positives = 154/308 (50%), Gaps = 17/308 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
R P+ G VIV ++V +VNS+N DF +D+++ + W +S L+ ++
Sbjct: 81 RTPSESG--VIVWIEVWVQEVNSVNEITSDFDMDIYVTELWMDSALRYEH--LNPCKYNL 136
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+L E D +W P+ F+NSK I + K + +Y N TV + R+ C M+F
Sbjct: 137 SLNSEILDQIWKPNTVFINSKSANIHKSPFKNVFLMIYPNGTVWVNYRVQVKGPCSMDFS 196
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQP----LRLEETNG 177
+PMD QSC + +ESFSY+NQ+V +W + L LL+ I P +
Sbjct: 197 AFPMDQQSCHLTLESFSYNNQEVDMQW----MNWTTPLSLLKKEIVLPDFVMSNYSTSLK 252
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
+ I G ++ L + F F R+ G ++ Q + P+ L + +SW SF L IP R
Sbjct: 253 HEIYPAGVWNELTMTFVFSRRYGWYIFQAYIPTYLTIFISWISFCLGPKMIPARTMLGVN 312
Query: 238 XXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL-----DKQYQM 292
F + ++P V+YVKALD+WM C+ FVF +L E ++ + ++Q Q
Sbjct: 313 SLLALTFQFGNIMRNLPRVSYVKALDVWMLVCLTFVFCSLLELAIIGSMGARSENRQAQQ 372
Query: 293 NKNKAQES 300
K + +E+
Sbjct: 373 QKQQDEEA 380
Score = 34.7 bits (76), Expect = 4.6
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
EID+LS ++FP LF LF +YW L
Sbjct: 488 EIDRLSMIMFPGLFTLFNIIYWTYYL 513
>UniRef50_Q4V4V5 Cluster: IP12579p; n=6; Endopterygota|Rep: IP12579p
- Drosophila melanogaster (Fruit fly)
Length = 612
Score = 157 bits (382), Expect = 4e-37
Identities = 88/288 (30%), Positives = 141/288 (48%), Gaps = 10/288 (3%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVT 62
P +G P +V+ +I + + ++ DMD+ +D + RQ W + RL I ++
Sbjct: 125 PTHGQGVPTVVQTNILIRSMGPVSELDMDYSMDCYFRQYWRDKRLSFKGPI-----KSLS 179
Query: 63 LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQL 122
L + D +W PD YF N K ++I +T + L +N + YS R+ C ME Q
Sbjct: 180 LSIKMLDKIWRPDTYFYNGKHSQIHMITVPNKLLRLDQNGGILYSMRLTIKATCPMELQN 239
Query: 123 YPMDIQSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
+PMD QSCP+ I S+ Y NQ++ + W + V+ P + L Q+ + + + N +
Sbjct: 240 FPMDRQSCPLVIGSYGYINQQLIYEWKNQDDAVSFVPGMTLNQFDL---ISMMHRNFTTV 296
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
++G++S L V F +R G+ LIQ + P L+V+LSW SFW+ +A R
Sbjct: 297 RREGDFSVLHVAFNLKRHTGYFLIQVYVPCILIVVLSWVSFWIHREATSDRVSLCVTSVL 356
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDK 288
R D+P V Y ALD ++ ++ A L EF V K
Sbjct: 357 TLSTISLDSRTDLPKVKYATALDWFLLMSFLYCIATLLEFAGVHYFTK 404
>UniRef50_P28476 Cluster: Gamma-aminobutyric acid receptor subunit
rho-2 precursor (GABA(A) receptor subunit rho-2); n=99;
Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit rho-2 precursor (GABA(A) receptor subunit rho-2)
- Homo sapiens (Human)
Length = 465
Score = 157 bits (381), Expect = 5e-37
Identities = 84/300 (28%), Positives = 148/300 (49%), Gaps = 6/300 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
PA G + V + V ++SI+ DMDF + +++R W + RL + +T
Sbjct: 70 PAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSS----ASNKSMTF 125
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F++SK + + T + ++ + V YS R+ C M+F +
Sbjct: 126 DGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHF 185
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL-LQYHIGQPLRLEETNGYMIDK 182
P+D Q+C + +ES++Y+++ + W ++ + K+ L + Q +
Sbjct: 186 PLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFY-SS 244
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+RL + F R I L+QT+ P++L+VMLSW SFW+D A+P R
Sbjct: 245 TGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTM 304
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMP 302
TG+ A +P V+YVKA+D+++ +FVF ++ E+ V L + + K +E P
Sbjct: 305 TTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKFP 364
>UniRef50_Q9GQ00 Cluster: Serotonin-gated chloride channel; n=4;
Caenorhabditis|Rep: Serotonin-gated chloride channel -
Caenorhabditis elegans
Length = 489
Score = 157 bits (380), Expect = 7e-37
Identities = 87/309 (28%), Positives = 151/309 (48%), Gaps = 9/309 (2%)
Query: 11 VIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDN 70
V V I+V D+ S+N DF +D+ Q W +S L ++T+
Sbjct: 56 VQVNIEIHVQDMGSLNEISSDFEIDILFTQLWHDSALSFAH--LPACKRNITMETRLLPK 113
Query: 71 LWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSC 130
+W P+ +NSK T + + V LY N TV + R+ C ++ + +P D Q+C
Sbjct: 114 IWSPNTCMINSKRTTVHASPSENVMVILYENGTVWINHRLSVKSPCNLDLRQFPFDTQTC 173
Query: 131 PIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLV 190
+ ES+S+++++V W E VT+ ++L + + +ET ++ +G + +L
Sbjct: 174 ILIFESYSHNSEEVELHWMEEAVTLMKPIQLPDFDMVHYSTKKET---LLYPNGYWDQLQ 230
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
V F F+R+ G ++IQ + P+ L +++SW SF ++ A+P R F +
Sbjct: 231 VTFTFKRRYGFYIIQAYVPTYLTIIVSWVSFCMEPKALPARTTVGISSLLALTFQFGNIL 290
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDK-QYQMNKNKAQESMPRIIPVRL 309
++P V+YVKA+D+WM GC+ FVF + E V + + Q + + + R V
Sbjct: 291 KNLPRVSYVKAMDVWMLGCISFVFGTMVELAFVCYISRCQNSVRNAERRRERMRNSQVWA 350
Query: 310 NGDKGSCGT 318
N GSC T
Sbjct: 351 N---GSCRT 356
>UniRef50_P78334 Cluster: Gamma-aminobutyric acid receptor subunit
epsilon precursor (GABA(A) receptor subunit epsilon);
n=30; Eutheria|Rep: Gamma-aminobutyric acid receptor
subunit epsilon precursor (GABA(A) receptor subunit
epsilon) - Homo sapiens (Human)
Length = 506
Score = 157 bits (380), Expect = 7e-37
Identities = 92/304 (30%), Positives = 145/304 (47%), Gaps = 15/304 (4%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +V I V + +++ DM++ +D+ QTW + RL D FE + L
Sbjct: 93 KPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLCY-NDTFES----LVLNGNVV 147
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
LW PD +F NSK T E+T V +Y++ V Y+ RM C + +PMD
Sbjct: 148 SQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSH 207
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPE--LKLLQYHIGQPLRLEETNGYMIDKDGNY 186
SCP+ SFSY ++ ++W + IN + KL Q+ + + G++
Sbjct: 208 SCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDF---TGVSNKTEIITTPVGDF 264
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
+ ++F R+ G+ Q + PSS+ MLSW SFW+ ++ P R
Sbjct: 265 MVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLG 324
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRIIP 306
T R + P V+Y+ ALD ++A C +F F AL EF V+ L N+ KA S P++
Sbjct: 325 TFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL----IYNQTKAHAS-PKLRH 379
Query: 307 VRLN 310
R+N
Sbjct: 380 PRIN 383
>UniRef50_O46123 Cluster: GBR-2A protein precursor; n=3;
Chromadorea|Rep: GBR-2A protein precursor - Haemonchus
contortus (Barber pole worm)
Length = 421
Score = 156 bits (379), Expect = 9e-37
Identities = 84/304 (27%), Positives = 151/304 (49%), Gaps = 10/304 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLP--EDIFEEGDDHVTLPP 65
G PV+V +IY+ ++ I+ +M++ R+ W ++RL ED E V L
Sbjct: 64 GGPVLVTVNIYLRSISKIDDVNMEYSAQFTFREEWVDARLAYGRFEDESTEVPPFVVLAT 123
Query: 66 ----EFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+ +W PD +F N KV + + ++++ ++ YS R+ +++C M +
Sbjct: 124 SENADQSQQIWMPDTFFQNEKVARRHLIDKPNVLIRIHKDGSILYSVRLSLVLSCPMSLE 183
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMID 181
YP+D Q+C I + S+ Y+ Q +++ W E + + L Q L+ + Y
Sbjct: 184 FYPLDRQNCLIDLASYGYTTQDIKYEWKEQN-PVQQKDGLRQSLPSFELQ-DVVTKYCTS 241
Query: 182 KD--GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
K G YS L R+ ++L+Q + PS ++V++SW SFWLD D++P R
Sbjct: 242 KTNTGEYSCLRTQMVLRREFSYYLLQLYIPSFMLVIVSWVSFWLDKDSVPARVTLGVTTL 301
Query: 240 XXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQE 299
+G+ A++PPV+Y KA+D+W+ C+ F+F AL EF V ++ + +
Sbjct: 302 LTMTTQSSGINANVPPVSYTKAIDVWIGVCLAFIFGALLEFAWVNYAARKDMSCGQRMMK 361
Query: 300 SMPR 303
+P+
Sbjct: 362 QLPQ 365
>UniRef50_A7S8M2 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 303
Score = 156 bits (378), Expect = 1e-36
Identities = 85/291 (29%), Positives = 150/291 (51%), Gaps = 12/291 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP PV ++ +++ V+ +V +M++ + ++IRQ W + RL D+F E D
Sbjct: 18 VRPTYPDNGPVNIQVDLFIQSVSKFSVINMEYSMTLYIRQRWLDQRLAYG-DMFPE--DF 74
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSS-VTLYRNQTVRYSARMHAIIACQME 119
+TL E +W PD Y +N K + + H S + + RN +V +SA ++ CQM+
Sbjct: 75 ITLGQEMVSQIWTPDTYIVNKKQS-MTNSGHGMSMFIRISRNGSVIFSAENTLVLVCQMD 133
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRW----SEAGVTINPELKLLQYHIGQPLRLEET 175
+ +PMD Q C IES+ ++ + V ++W + + L ++ I +E
Sbjct: 134 LRNFPMDEQQCDFKIESYGFTMKDVVYKWLDDPKQKTIETAEGLDATEFSIVSLKTMENI 193
Query: 176 NGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXX 235
+ + + GN+S L + +R+ +++IQ + P S++VMLSW SFWLD ++P R
Sbjct: 194 SVFNL---GNFSSLTMRIYLDRRTTYYVIQIYIPCSMIVMLSWISFWLDYKSVPARTALG 250
Query: 236 XXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
G+++ +P V Y+KA+D ++ VF AL EF VV +
Sbjct: 251 ITTVLAMTTLLFGIQSSLPGVPYIKAVDQFLIVSFACVFVALIEFAVVNFI 301
>UniRef50_Q9Y0I3 Cluster: Ionotropic GABA receptor subunit
UNC-49B.3; n=11; Eumetazoa|Rep: Ionotropic GABA receptor
subunit UNC-49B.3 - Caenorhabditis elegans
Length = 506
Score = 155 bits (376), Expect = 2e-36
Identities = 86/300 (28%), Positives = 153/300 (51%), Gaps = 11/300 (3%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPE-DI-FEEGDDHVTLPPE 66
+PV V +I+V +++++ DMDF +D ++RQTW + RL D+ + D +T+ +
Sbjct: 58 KPVDVGITIHVSSISAVSEVDMDFTLDFYMRQTWQDPRLAFGSLDLGLSKEIDSLTVGVD 117
Query: 67 FFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMD 126
+ D LW PD +F N K + T S + + + TV S R+ C M+ +L+PMD
Sbjct: 118 YLDRLWKPDTFFPNEKKSFFHLATTHNSFLRIEGDGTVYTSQRLTVTATCPMDLKLFPMD 177
Query: 127 IQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMID----- 181
Q C + IES+ Y + + + W + + E+ +++ Q + + T Y ++
Sbjct: 178 SQHCKLEIESYGYETKDIDYYWGKKRTDL--EITAVKFDTFQLPQFQPTL-YFVNTTKAE 234
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G Y RL + R +G + + PS L+V +SW SFWL+ +A P R
Sbjct: 235 TSSGKYVRLALEVILVRNMGFYTMNIVIPSILIVTISWVSFWLNREASPARVGLGVTTVL 294
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQES 300
T +P V+YVK LD+++ C + VFA+L E+ +V ++K+ + + K +++
Sbjct: 295 TMTTLITTTNNSMPKVSYVKGLDVFLNFCFVMVFASLLEYAIVSYMNKRLVLRREKRRKA 354
>UniRef50_Q25035 Cluster: GABA A/glycine receptor subunit; n=3;
Rhabditida|Rep: GABA A/glycine receptor subunit -
Haemonchus contortus (Barber pole worm)
Length = 472
Score = 155 bits (376), Expect = 2e-36
Identities = 113/413 (27%), Positives = 181/413 (43%), Gaps = 13/413 (3%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP P+ VE I V + I+ +DM+F +D + RQ W + RL +
Sbjct: 52 RPTNPDSSPLNVEIDISVRSMGPISEQDMEFSLDCYFRQKWLDRRLAFTP--INPDKPVM 109
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
L + ++W PD Y N + + + LT + + V S R+ C M +
Sbjct: 110 PLASKMLKDIWVPDTYIRNGRKSYLHTLTVPNILFRVRSDGQVHVSQRLTIKTKCLMFLK 169
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMID 181
+PMD+Q+CPI I S Y + V + W + + L QY I + E +
Sbjct: 170 KFPMDVQACPIEIGSLGYFSNDVVYYWKDVELDAKMGNMLSQYKILGLFKSEHNFSDHRE 229
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
N S L VYF+ +RQ G++++Q + P +L+V++SW SFW++ +A P R
Sbjct: 230 IGRNISVLKVYFKLQRQQGYYVLQIYTPCTLLVVMSWVSFWINKEASPARVALGIMTVLS 289
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY---QMNKNKAQ 298
GLR D+P V++ ALD+++ C FVFAA+ E+ V+ Y Q++ K
Sbjct: 290 MSTLGFGLRTDLPKVSHSTALDIYILSCFGFVFAAMVEYSVINYAQIVYIRKQVHDLKGL 349
Query: 299 ESMPRIIPVRLNGDKGSCGTIAAWEGSGVRCRKVDIXXXXXXXXXXXXXXXXXXXXXXXX 358
ES + +RL G G A E V +D
Sbjct: 350 ESNRAMEKMRL-FTAGLMG--ARRETIQVDDLVLDEEEDLPWYSCFFRKKTKKQSSMFYR 406
Query: 359 XGVERRQSILQVAWLDADTGQERVLWREIDKLSRVVFPALFLLFVTMYWPVLL 411
V+ ++ ++ D RV D +S+V+FP+L++LF +YW L
Sbjct: 407 MAVKAAKARRKLKMKDPAKVVNRV-----DDVSKVIFPSLYVLFNILYWVAFL 454
>UniRef50_A7SFV7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 428
Score = 155 bits (376), Expect = 2e-36
Identities = 84/290 (28%), Positives = 150/290 (51%), Gaps = 16/290 (5%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEG-DDHVT 62
P G+PV+V+ +++ V+SI+V +MDF VD+F+RQ W + RL + G ++ +
Sbjct: 52 PFYNGKPVVVKVGYWILSVDSIDVVNMDFTVDLFLRQEWVDPRL-------DHGLNETIY 104
Query: 63 LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQL 122
L +W PD YFLN+K ++ +T + V+Y+ R+ AC ++ +
Sbjct: 105 LGHRVMQKIWTPDSYFLNAKTAKMHHVTTPNQMTLIAPMGVVKYNTRVTVKAACTIDLRS 164
Query: 123 YPMDIQSCPIYIESFSYSNQKVRFRW---SEAGVTINPE-LKLL-QYHIGQPLRLEETNG 177
+PMD Q+CP+ +ES+ Y + + W + G+ P ++++ QY + + E +
Sbjct: 165 FPMDQQNCPLVLESYGYDRSHIVYHWEGNATDGLPFVPNRMRIMPQYSLVRLTLSREWHQ 224
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
Y+I GN+S +V F ER + L + S ++V +SW F + D R
Sbjct: 225 YII---GNFSAVVAVFSIERSYTYFLTHVYGTSCVIVFISWMGFVIPPDQTAARIAVGVT 281
Query: 238 XXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLD 287
L + +P V+YVK++D ++ C++FVF +L E+ V+ +LD
Sbjct: 282 TLLTQVTVINILNSSMPKVSYVKSIDKFLISCLIFVFLSLIEYCVILILD 331
>UniRef50_Q9N517 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 382
Score = 153 bits (372), Expect = 6e-36
Identities = 81/284 (28%), Positives = 145/284 (51%), Gaps = 18/284 (6%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL-PPEFF 68
P+ V F YV + + +M + +DM++ +W + ++ E +HV + +
Sbjct: 10 PLQVHFGFYVESLGNFRATEMTYDMDMYLYMSWQDDSMRHNET------EHVLVNDKDIL 63
Query: 69 DNLWHPDPYFLNSKVTEIAELT-HKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D +W PD YF N++ ++T H F+ + + T+ Y R+ +AC ++ + YP+D
Sbjct: 64 DKIWLPDLYFANARTAYFHKVTVHNFN-MFISPQGTISYGTRVTLNLACNLDLKDYPLDY 122
Query: 128 QSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMI------ 180
Q+C I + S+++ ++ W + NPE+ L ++HI + L + NG +
Sbjct: 123 QTCYIKVISYAHVKNEMNVSWFPNDPIRFNPEIDLPEFHI-RALDKDYCNGVFLYTLTHN 181
Query: 181 -DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
+ G +S L+ + +R IG HL+Q++ P+ L+V +SW SFW+D A+P R
Sbjct: 182 SSRVGEFSCLLGMLKLKRAIGFHLVQSYIPTGLIVAISWVSFWIDRRAVPARVSLSFTTL 241
Query: 240 XXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
G+R +P V+Y KA+D + CM+F+F L EF V
Sbjct: 242 LTLSTQGNGIRYALPAVSYAKAIDYFYGVCMLFIFGVLLEFAAV 285
>UniRef50_P91985 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 400
Score = 152 bits (368), Expect = 2e-35
Identities = 94/304 (30%), Positives = 153/304 (50%), Gaps = 12/304 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G V VEF ++ ++NSI+ DF +++FI + W++ L+ P ++TL
Sbjct: 90 PRENGITVSVEF--WIQEINSISEMTNDFELELFINEMWTDPSLRFPH--LGACKANLTL 145
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+ LW P+ F+NSK EI E + + +TL+ N TV + R+ AC M+ +
Sbjct: 146 DQQTLTKLWTPNTCFVNSKFAEIYESSFQNVFLTLFDNGTVWVNYRVRVKGACNMDLVDF 205
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD 183
PMD QSC + +SF+Y+N++VR +W+ +P L + I L++ +I +D
Sbjct: 206 PMDTQSCRLNYQSFTYNNEEVRLQWNSQR---SPVFALQEIRIAD-FWLKDITPAVIKRD 261
Query: 184 ---GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G + LVV F FER+ + +Q + P+ + +SW +F L AI R
Sbjct: 262 YPAGLWDELVVTFVFERRYMWYFLQAYLPTFFSIFISWIAFSLGPQAITPRTMIGVNALL 321
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQES 300
F + ++P V+Y+KA+D+WM M FVF +L E +V Q Q K E
Sbjct: 322 SMIFHFGSIMKNLPRVSYIKAIDVWMLSSMTFVFLSLIELAIVG-YKLQIQREKEHVIEK 380
Query: 301 MPRI 304
+ +I
Sbjct: 381 VDKI 384
>UniRef50_UPI00015B4D8A Cluster: PREDICTED: similar to
glutamate-gated chloride channel; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to glutamate-gated
chloride channel - Nasonia vitripennis
Length = 510
Score = 151 bits (365), Expect = 4e-35
Identities = 88/306 (28%), Positives = 151/306 (49%), Gaps = 12/306 (3%)
Query: 1 MRPPARKGQ--PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGD 58
+RP G P IV +++V + +I+ M++ V + R+ W + RL+ + F
Sbjct: 51 IRPSGENGTDGPAIVRVNLFVRSIATISDIKMEYSVQLTFREQWVDERLRFND--FGGKL 108
Query: 59 DHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQM 118
++TL +W PD +F N K + + ++ + +V YS R+ ++C M
Sbjct: 109 KYLTLTDA--SRVWMPDLFFANEKEGHFHNIIMPNVYIRIFPDGSVLYSIRISLTLSCPM 166
Query: 119 EFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNG 177
+LYP+D Q C + + S+ ++ + F W E V + L L ++ + + L + N
Sbjct: 167 NLKLYPLDRQICSLRMASYGWTTADLVFLWKEGDPVQVVKNLHLPRFTLEKFLT-DYCNS 225
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
G YS L V F+R+ ++LIQ + P ++V++SW SFWLD A+P R
Sbjct: 226 KT--NTGEYSCLKVDLLFKREFSYYLIQIYIPCCMLVIVSWVSFWLDQSAVPARVSLGVT 283
Query: 238 XXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ--YQMNKN 295
+G+ A +PPV+Y KA+D+W C+ FVF AL EF +V + ++ N
Sbjct: 284 TLLTMATQTSGINASLPPVSYTKAIDVWTGVCLTFVFGALLEFALVNYASRSDIHRENMK 343
Query: 296 KAQESM 301
K + M
Sbjct: 344 KKYQEM 349
>UniRef50_Q8WSF7 Cluster: GABA A receptor alpha subunit; n=1;
Aplysia californica|Rep: GABA A receptor alpha subunit -
Aplysia californica (California sea hare)
Length = 448
Score = 151 bits (365), Expect = 4e-35
Identities = 87/289 (30%), Positives = 146/289 (50%), Gaps = 13/289 (4%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G+ + V I + + I+ +M + +D + RQ W + RL + + +++TL
Sbjct: 51 PGFGGEALTVNADISLRSMGPISELNMIYTLDCYFRQRWMDHRLAMNVSL-----ENLTL 105
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+ + +WHPD F N + + + +T + + N TV +S R+ C+M + +
Sbjct: 106 GIKILERIWHPDTVFYNGQKSYLHAITSHNRFLRIAANGTVLFSQRLTIQATCRMHPENF 165
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWS---EAGVTINPELKLLQYH-IGQPLRLEETNGYM 179
PMDIQ CP+ I SF+YS V ++W + + + P+L+L Q+ +G PL TN
Sbjct: 166 PMDIQHCPLLIGSFAYSTDDVIYKWRYGLQGSIELAPDLRLSQFDLVGYPL----TNYTG 221
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
+ K +S L V F+ R G+ LI + P L+V+LSW SFW++ +A R
Sbjct: 222 LVKGAVHSVLCVTFQLSRHTGYFLINLYLPCCLLVVLSWASFWINREATADRIALGSTTV 281
Query: 240 XXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDK 288
++ +P V+Y+ ALD+++A C +FV A EF VV K
Sbjct: 282 LTMTILGIENKSQLPKVSYITALDVYVALCFVFVIATTIEFAVVHYFTK 330
>UniRef50_UPI0000E4758B Cluster: PREDICTED: similar to GABA-gated
chloride channel; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to GABA-gated
chloride channel - Strongylocentrotus purpuratus
Length = 530
Score = 149 bits (362), Expect = 1e-34
Identities = 76/264 (28%), Positives = 131/264 (49%), Gaps = 10/264 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G P+ V S+YV + I M++ +DM+ RQ W + RLQ ++ + L
Sbjct: 66 PGFGGPPIDVTVSMYVYSMGPITESKMEYTLDMYFRQQWRDERLQFDSEV------GLAL 119
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
E D+ W PD Y +N K + +K S + + + +S R+ +C M+ +
Sbjct: 120 NAETLDSFWVPDIYIINEKSAAYHTVLYKNSLLRIEPTGEMLFSTRLTVTASCNMDLSTF 179
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNGYMIDK 182
P D Q C + +ES++YS V+F+W E G V ++P++ L Q+ Y +
Sbjct: 180 PFDKQRCSLDMESYAYSEDDVKFKWLENGPVYVDPKISLPQFKFLDSSVRSRIAEYFV-- 237
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
GNY+ + F R I ++++QT+ PSS++ LSW SFW++ +A+P R
Sbjct: 238 -GNYTVVSADFYLGRDITYYVVQTYIPSSMITCLSWLSFWINRNAVPARVALGITTVLTM 296
Query: 243 XXXFTGLRADIPPVAYVKALDLWM 266
+P ++Y+KA+DL++
Sbjct: 297 TTLVGNAGNSLPKLSYIKAIDLFL 320
>UniRef50_UPI0000E47589 Cluster: PREDICTED: similar to
gamma-aminobutyric acid A receptor beta 2S chain
precursor - chicken; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to gamma-aminobutyric
acid A receptor beta 2S chain precursor - chicken -
Strongylocentrotus purpuratus
Length = 418
Score = 149 bits (362), Expect = 1e-34
Identities = 75/255 (29%), Positives = 133/255 (52%), Gaps = 10/255 (3%)
Query: 31 DFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELT 90
D+ + M+ RQ W + RL ++ +V+L + +W PD YF N K + + ++T
Sbjct: 3 DYTLTMYFRQHWKDERLS-----YDPCLGNVSLSGILAERIWVPDTYFPNDKRSFVHDVT 57
Query: 91 HKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSE 150
+ + + T+ Y R+ ++ +C M+ YPMD Q+C + IES+ Y+ V F W
Sbjct: 58 VTNKLLRFHHDGTITYGMRITSVASCYMDLVHYPMDEQNCSLEIESYGYTTADVNFVWQY 117
Query: 151 AGVTINP--ELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFA 208
++ +++ Q+ + + + + G+Y RL + FR +R +G +QT+
Sbjct: 118 GDDSLEGVNNIEMAQFTLSDYKLIVKMQNF---STGSYPRLALTFRIKRNVGFFFLQTYL 174
Query: 209 PSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAG 268
PS L+VMLSW SFW++ +A R T +R +P ++YVK++D+++
Sbjct: 175 PSILLVMLSWVSFWINHEATSARVSLGITTVLTMTTISTAVRQSLPRISYVKSIDIYVIT 234
Query: 269 CMMFVFAALGEFVVV 283
C FVFAAL E+ +V
Sbjct: 235 CYSFVFAALVEYAIV 249
Score = 35.1 bits (77), Expect = 3.5
Identities = 12/21 (57%), Positives = 18/21 (85%)
Query: 387 IDKLSRVVFPALFLLFVTMYW 407
+D++SR++FP LFLLF +YW
Sbjct: 384 VDRVSRILFPFLFLLFNVLYW 404
>UniRef50_Q95Y52 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 508
Score = 149 bits (362), Expect = 1e-34
Identities = 84/300 (28%), Positives = 147/300 (49%), Gaps = 6/300 (2%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G V VE ++V ++ +I+ DF++D++I +TW + L +++L
Sbjct: 84 GGQVDVEVEVWVQEITTISDITSDFQLDIYIYETWYDPALNYA--FMNPCKYNLSLNSVL 141
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW P+ F+NSK +I + + +Y N TV + R+ C M+ +P D
Sbjct: 142 LEKLWTPNSCFINSKTADIHKSPFPNIFLMIYANGTVWTNYRLKLQGPCIMDLTKFPFDN 201
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVT-INPELKLLQYHIGQPLRLEETNGYMIDKDGNY 186
+C + ESF+Y+ +V+ WS GV + +++L Y + ++ T Y G +
Sbjct: 202 VTCSLTFESFNYNTDEVKMDWSVNGVQKMRDKMELADYELVDIHKIRTTEEYPA---GYW 258
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
L + F F+R+ G +++Q + P+ L + +SW SF L AIP R F
Sbjct: 259 HELTMSFEFKRRAGWYILQAYLPTYLTICISWISFALGSKAIPARTMLGVNSLLAMTFQF 318
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRIIP 306
+ ++P V+YVKA+D+WM CM FVF +L E V L ++ + K + ++ P
Sbjct: 319 GNIIRNLPRVSYVKAIDVWMLSCMTFVFCSLLELAWVGYLSREEEPTSAKCLQPSAQVAP 378
>UniRef50_A7SJ14 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 291
Score = 149 bits (361), Expect = 1e-34
Identities = 89/281 (31%), Positives = 142/281 (50%), Gaps = 16/281 (5%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRL--QLPEDIFEEGDDHVTLPP 65
G+PV+V IY+V++ I+V +MD+++ ++ RQTW + RL LPE I +G
Sbjct: 19 GKPVVVYVDIYIVNIGEISVTNMDYKLMLYYRQTWHDPRLAFDLPEAITVQGG------- 71
Query: 66 EFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPM 125
+++W PD F N K + ++T ++++ N T S R+ C M+ + YPM
Sbjct: 72 -MLNDIWIPDTLFTNEKSSTFHKVTQDNYLLSIWPNGTTYLSMRISLTGICPMDLRKYPM 130
Query: 126 DIQSCPIYIESFSYSNQKVRFRWS--EAG-VTINPELKLLQYHIGQPLRLEETNGYMIDK 182
D Q+C + I S+S S + +W E G VT + L Q + L ++ +
Sbjct: 131 DTQTCYLNIMSYSGSTDNLILKWKFGETGSVTWAENINLPQMDV---LGVKGREVVDVFA 187
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
GNYSRL + F+F+R+I L +T+ P L+V LSW SFW++ P R
Sbjct: 188 SGNYSRLSLAFKFKRRISLFLTETYVPLVLIVALSWVSFWINYKVAPARVALCITTVLTI 247
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+R +P V Y K D + +++VF AL E+ VV
Sbjct: 248 ITLSASVRTSLPKVTYTKYSDWILITGLVYVFGALVEYAVV 288
>UniRef50_O01792 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 469
Score = 149 bits (360), Expect = 2e-34
Identities = 81/299 (27%), Positives = 139/299 (46%), Gaps = 6/299 (2%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V+ + V DV ++V F D++ W + RL + +++ F
Sbjct: 49 GNPVGVQVEVTVQDVMELSVLSNSFTADIWFSSIWYDPRLAYSH--LDNCRQNLSFDDRF 106
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+W P+ +N+K + + L N T+ + R+ C M+ +P+D
Sbjct: 107 EKLIWSPNVCIVNTKSAHVHRSPKPNVLLMLLPNGTIWLNYRIRVQSPCSMDLARFPIDT 166
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYS 187
Q C + ES+SY+ V W VT+ PE+ L + + + T Y K G +
Sbjct: 167 QYCQLVFESYSYNTASVSVNWMANPVTVLPEISLADFDLSRYRTSRHTEVY---KAGEWY 223
Query: 188 RLVVYFRFERQIGHHLIQT-FAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
RL V F F R+ G +++Q + P+ + + +SW +F +D A+P R F
Sbjct: 224 RLTVEFEFTRKYGFYILQVLYVPTYISLFISWIAFCIDTKALPARIVLGVNSLMSLTFQF 283
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRII 305
+ +PPV+YVKA+DLWM C+ F+FA+L E V DK+ + K+ ++ ++
Sbjct: 284 GNIIRSLPPVSYVKAIDLWMCTCVGFIFASLLELAFVAYQDKKLILKSGKSNAAISTLV 342
>UniRef50_A7SAS4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 293
Score = 147 bits (357), Expect = 4e-34
Identities = 78/280 (27%), Positives = 140/280 (50%), Gaps = 16/280 (5%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G P+ + + VV +++ +DM+F +D+F +Q W + RL+ LP
Sbjct: 26 GPPLNISVYMSVVSFSTVYEKDMEFSLDVFFKQAWRDPRLR------HSAKMPFILPGSQ 79
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ W PD +FLN K ++ + + + + + S R+ +C+M+ ++YP+D
Sbjct: 80 KEKFWIPDTFFLNVKTARFHQVPAANTRIVVTPDGDIELSERLTVSASCRMDLRMYPLDQ 139
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD---- 183
Q+C + I S+S+ + +RW +L +L + + L+++ G K
Sbjct: 140 QTCVLEILSYSFDINDIDYRWKA-----KEDLIILDGEMNE-FELKDSRGERKQKSRSCT 193
Query: 184 GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXX 243
G Y+ LV F F R++ + IQ ++P+ L+V+LSW SFW+ DA+P R
Sbjct: 194 GTYTHLVAKFVFRRRLAYSFIQIYSPTFLIVVLSWLSFWISKDAVPARVALGITTVLTIV 253
Query: 244 XXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
LR +P V+Y+KA+DL++ +FVF L E++ V
Sbjct: 254 TLMGSLRNSVPKVSYIKAIDLYLIVSFIFVFGTLLEYIAV 293
>UniRef50_P48169 Cluster: Gamma-aminobutyric acid receptor subunit
alpha-4 precursor (GABA(A) receptor subunit alpha-4);
n=26; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit alpha-4 precursor (GABA(A) receptor subunit
alpha-4) - Homo sapiens (Human)
Length = 554
Score = 146 bits (354), Expect = 9e-34
Identities = 91/301 (30%), Positives = 144/301 (47%), Gaps = 16/301 (5%)
Query: 8 GQPVI-VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPE 66
G PV V+ IYV ++ +M++ +D+F RQTW + RL+ I + + L
Sbjct: 68 GGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPI-----EILRLNNM 122
Query: 67 FFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMD 126
+W PD +F N K + +T + RN T+ Y+ R+ C M +PMD
Sbjct: 123 MVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMD 182
Query: 127 IQSCPIYIESFSYSNQKVRFRWS---EAGVTINPE-LKLLQYH-IGQPLRLEETNGYMID 181
+CP+ S++Y ++ + W+ E V + E L+QY IGQ + E
Sbjct: 183 GHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSI--- 239
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
G Y + VYF R++G+ +IQT+ P + V+LS SFW++ +++P R
Sbjct: 240 -TGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLT 298
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESM 301
R +P V+Y+ A+D ++A C FVF+AL EF V QM K K + S
Sbjct: 299 MTTLSISARHSLPKVSYLTAMDWFIAVCFAFVFSALIEFAAVNYF-TNIQMEKAKRKTSK 357
Query: 302 P 302
P
Sbjct: 358 P 358
>UniRef50_P31644 Cluster: Gamma-aminobutyric acid receptor subunit
alpha-5 precursor (GABA(A) receptor subunit alpha-5);
n=86; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit alpha-5 precursor (GABA(A) receptor subunit
alpha-5) - Homo sapiens (Human)
Length = 462
Score = 146 bits (353), Expect = 1e-33
Identities = 85/294 (28%), Positives = 143/294 (48%), Gaps = 15/294 (5%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V IYV ++ +M++ +D+F RQ+W + RL+ F+ + L +W
Sbjct: 75 VRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLR-----FKGPMQRLPLNNLLASKIW 129
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + L + T+ Y+ R+ C M+ + +PMD +CP+
Sbjct: 130 TPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPL 189
Query: 133 YIESFSYSNQKVRFRWSEAG----VTINPELKLLQYHI-GQPLRLEETNGYMIDKDGNYS 187
S++Y N +V + W+ V +L QYH+ GQ + E + G Y+
Sbjct: 190 KFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENIS----TSTGEYT 245
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
+ +F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 246 IMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI 305
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ-YQMNKNKAQES 300
R +P VAY A+D ++A C FVF+AL EF V K+ + + KA E+
Sbjct: 306 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEA 359
Score = 34.3 bits (75), Expect = 6.0
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+IDK+SR+VFP LF F +YW L
Sbjct: 424 KIDKMSRIVFPVLFGTFNLVYWATYL 449
>UniRef50_UPI0000E48505 Cluster: PREDICTED: similar to inhibitory
glycine receptor; n=1; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to inhibitory glycine
receptor - Strongylocentrotus purpuratus
Length = 431
Score = 145 bits (351), Expect = 2e-33
Identities = 83/303 (27%), Positives = 145/303 (47%), Gaps = 14/303 (4%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G V V +++ ++ I+ + +D+ + I Q W + RL + TL
Sbjct: 54 PCVNGDAVHVFLDVFLASLDGIDEKHLDYSITATIHQRWHDPRLTF--------NGTTTL 105
Query: 64 PPEFF--DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
PP + D +WHP+ N+K + ++ VT+ + V R+ ++C M+F
Sbjct: 106 PPTAYLVDRVWHPNIVIGNAKEVLLHHISDTNQYVTVDWDGNVTLVQRLSVKLSCAMDFH 165
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPE-LKLLQYHIGQPLRLEETNGYMI 180
+PMD Q C + ++SF + + W + + ++L QY++ + T
Sbjct: 166 RFPMDTQKCNMDLQSFGLTTSDLVLLWGAQKLEFHSHHMRLPQYYMTGVDFFDCTEQRY- 224
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
+G +S + F ER +G++++Q F PS +VM+SW +FW+D+ A P R
Sbjct: 225 --NGIFSCVRAQFTLERTLGYYMLQAFIPSIALVMVSWVTFWIDVRASPARVGLGVTIIL 282
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQES 300
G+R DIPPV+Y+KA+D+W C+ FV AL E+ +V L + K K
Sbjct: 283 SVISKTNGVRLDIPPVSYLKAIDVWYTSCLFFVIGALLEYALVHHLSLGQKKTKQKVLAF 342
Query: 301 MPR 303
+P+
Sbjct: 343 IPK 345
>UniRef50_Q17328 Cluster: Glutamate-gated chloride channel subunit
beta precursor; n=8; Chromadorea|Rep: Glutamate-gated
chloride channel subunit beta precursor - Caenorhabditis
elegans
Length = 434
Score = 145 bits (351), Expect = 2e-33
Identities = 84/300 (28%), Positives = 148/300 (49%), Gaps = 10/300 (3%)
Query: 3 PPARKGQP--VIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
PPA V V +I + ++ I+V +M++ + + R+ W + RL F
Sbjct: 47 PPANSSTEGAVNVRVNIMIRMLSKIDVVNMEYSIQLTFREQWIDPRLAYENLGFYNPPAF 106
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+T+P +LW PD +F K + + + +Y + + YS+R+ +C M
Sbjct: 107 LTVP-HVKKSLWIPDTFFPTEKAAHRHLIDMENMFLRIYPDGKILYSSRISLTSSCPMRL 165
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKL-LQYHIGQPLRLEETNGY 178
QLYP+D QSC + S++++ + + W + V + P + L I L+ TN
Sbjct: 166 QLYPLDYQSCNFDLVSYAHTMNDIMYEWDPSTPVQLKPGVGSDLPNFI---LKNYTTNAD 222
Query: 179 MID--KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXX 236
G+Y L + F+RQ ++L+Q +AP++++V++SW SFW+DL + GR
Sbjct: 223 CTSHTNTGSYGCLRMQLLFKRQFSYYLVQLYAPTTMIVIVSWVSFWIDLHSTAGRVALGV 282
Query: 237 XXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
+ + A +PPV+YVK +D+W+ C FVF AL E+ V D Q ++++
Sbjct: 283 TTLLTMTTMQSAINAKLPPVSYVKVVDVWLGACQTFVFGALLEYAFVSYQDSVRQNDRSR 342
>UniRef50_Q621V5 Cluster: Putative uncharacterized protein CBG02331;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG02331 - Caenorhabditis
briggsae
Length = 472
Score = 144 bits (350), Expect = 3e-33
Identities = 86/302 (28%), Positives = 149/302 (49%), Gaps = 13/302 (4%)
Query: 11 VIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDN 70
V V + V D++SI+ F D++ Q W + RL+ + +++L +
Sbjct: 93 VQVSVELTVQDISSISEISSSFIADVWFSQVWEDPRLEYRNISCKT---NLSLDSYVSER 149
Query: 71 LWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSC 130
LW P+ F+NSK T++ + + +Y N TV + R+ C E +P+D Q C
Sbjct: 150 LWTPNVCFVNSKSTQVHKSPASNILLIIYPNGTVWLNYRVQVSAPCSFELSRFPIDAQEC 209
Query: 131 PIYIESFSYSNQKVRFRWSE-AGVTINP--ELKLLQYHIGQPLRLEETNGYMIDKDGNYS 187
+ ES+SY+ +VR W + A VT+ P + +L + + +N Y G +
Sbjct: 210 HLVFESYSYNIAEVRLNWQQWAPVTMPPPEDFRLPDFQFYNVTWGKTSNEYTA---GMWD 266
Query: 188 RLVV----YFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXX 243
+L V +FRF+R G++++Q + P+ L V +SW +FW+D A+P R
Sbjct: 267 QLKVTFSFFFRFKRLYGYYVLQMYLPTYLSVFISWIAFWIDTRALPARITLGVSSLMALT 326
Query: 244 XXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPR 303
F + ++P V++VKA+DLW C+ F+F +L E VV +DK ++ + + R
Sbjct: 327 FQFGNIVKNLPRVSFVKAIDLWFFVCVAFIFFSLVELAVVGFVDKITEIKRRSRRIKFQR 386
Query: 304 II 305
I
Sbjct: 387 AI 388
>UniRef50_A7S448 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 366
Score = 144 bits (348), Expect = 5e-33
Identities = 77/284 (27%), Positives = 146/284 (51%), Gaps = 12/284 (4%)
Query: 31 DFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELT 90
D+ +D+F RQ W + RL D+ + + P ++F W PD YF+N K ++ +T
Sbjct: 4 DYSLDIFFRQWWRDERLA--HDV-NKVFNMAANPGQYF---WTPDTYFVNVKSSKFHHVT 57
Query: 91 HKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSE 150
+ ++ + + YS+R+ +C+M+ + +PMD Q C + IES++Y+ + V + W+
Sbjct: 58 RENMRTKIWPDGLIYYSSRITLTASCEMDLRFFPMDTQDCVLKIESYAYTVEDVIYNWNN 117
Query: 151 AGVTINPELKLLQYHIGQPLRLEETNGYMIDKD---GNYSRLVVYFRFERQIGHHLIQTF 207
G T +++ + Q E T MI G++ L V FRF+R+ + ++Q +
Sbjct: 118 RGTT---PIEIFAGEMAQFDMTEMTMQTMITFSLLTGSFDSLRVSFRFKRRTSYFIVQHY 174
Query: 208 APSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMA 267
PS+ +V LSW FW++ +A+P R F + + +P ++Y+KA+D ++
Sbjct: 175 VPSAFIVFLSWLGFWINKNAVPARISLTVTCILSTMVLFESINSSLPRISYLKAVDYYLI 234
Query: 268 GCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRIIPVRLNG 311
MF+ A++ E+V+V + ++ ++ P R NG
Sbjct: 235 ISFMFILASMVEYVLVLNVTDYKRITLSRKHSLQPCHCRERSNG 278
>UniRef50_A7S2G2 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 270
Score = 144 bits (348), Expect = 5e-33
Identities = 74/266 (27%), Positives = 133/266 (50%), Gaps = 6/266 (2%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
GQPV + ++ + V + E MD+ + RQ W + RL + G H + E
Sbjct: 1 GQPVNITVNMRINSVFDVREEAMDYTMRFAFRQKWRDPRLTYNISL-TRGQGHPYIQLET 59
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D +W+PD +F+N++ + I ++T K + L+ + ++ S ++ CQM+ + +PMD
Sbjct: 60 ADLIWYPDTFFMNARKSYIHDVTKKNLGIRLFPDGSIYMSQKITVTAECQMDLRKFPMDT 119
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAG--VTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q C + ESF ++ ++ RW E V I+ ++ L + I + LE Y + K G
Sbjct: 120 QVCVLQFESFFHTAAEIVLRWEEGDTPVAISKDMNLPHFDI---VGLETKQIYNVYKSGK 176
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
++ L V+ F R++G++LIQT+ P + LSW FW+D R
Sbjct: 177 FNSLEVHITFRRRLGYYLIQTYLPCVFLCFLSWMPFWMDPSETGDRLAVGITAVLTIVFL 236
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMM 271
+ ++P V+Y+KA+D ++ C +
Sbjct: 237 AGAMNTNMPKVSYMKAIDWYVIACFL 262
>UniRef50_A7SCG0 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 286
Score = 143 bits (347), Expect = 7e-33
Identities = 80/277 (28%), Positives = 133/277 (48%), Gaps = 6/277 (2%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PVIV+ YV + +I+ + M+F VD+F RQ W E RL + + L P
Sbjct: 1 GGPVIVDVEAYVASIGAIDEKKMEFSVDIFFRQRWREERLCYLPQAGKGSGQRLILNPVL 60
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
N W PD + NSK E+ + + + S+R+ ++CQM F+ +PMD+
Sbjct: 61 LKNTWRPDVFIKNSKEARFHEVPSDNVMYGISPDGNILLSSRITTTLSCQMNFRRFPMDV 120
Query: 128 QSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNY 186
Q C S+ ++ + R G+ I+ E+++ QY I + + Y G +
Sbjct: 121 QKCHFQTGSYGHTEDDIVIRCRGGKGLIISDEVEISQYSITEVTSRDFKGVY---NTGVF 177
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
S + +R++ +++ + P+ LVV LSW SFW+D ++P R
Sbjct: 178 SEPIATIVLKRRLMYYVYGYYLPAGLVVFLSWISFWIDPRSVPARVSLGVITILAMGSFL 237
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
G + P V+Y ALD+++ C +FVF +L EF +V
Sbjct: 238 HGGKG--PSVSYATALDVYIISCYVFVFTSLLEFSLV 272
>UniRef50_UPI00015B49D8 Cluster: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to cys-loop
ligand-gated ion channel subunit - Nasonia vitripennis
Length = 513
Score = 142 bits (343), Expect = 2e-32
Identities = 81/303 (26%), Positives = 148/303 (48%), Gaps = 13/303 (4%)
Query: 1 MRPPARKG--QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGD 58
+RPP +PV V Y+ + S + + F V M ++ + ++RL+ +DI
Sbjct: 63 VRPPGELNDREPVKVWARAYIYTIKSNMAKTLQFDVHMMLQFRYLDTRLKF-DDIAPH-Q 120
Query: 59 DHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQM 118
+ + D +W P Y N + + I + K +++ + V + R+ AI+ C +
Sbjct: 121 NQIYGGQSAHDLIWTPSVYVANERSSVIMGNSVKDLLISIDPSGMVVLNTRLEAILNCGL 180
Query: 119 EFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGY 178
+ +P D+Q CP+ ES++++ Q + W EA + + EL L +Y + + Y
Sbjct: 181 RLEKFPFDVQECPMVFESWTHNVQDMILNWDEAPIVLADELHLTEYRLVEQWVNRSEVSY 240
Query: 179 MIDKD------GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRX 232
+ GN+S + + F+ R++G ++ + PS L+V++SW SFWL +DA P R
Sbjct: 241 TTAQQHYGHFAGNFSSISITFKLAREMGFFMMDYYIPSILIVVISWVSFWLHVDASPPRI 300
Query: 233 XXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQM 292
+ + +P V+Y+KA ++W GC +F+FAA+ EF V + Y+
Sbjct: 301 VLGTNTILAFMTLASKVENSLPKVSYIKASEIWFLGCTIFLFAAMVEFAFVNTI---YRR 357
Query: 293 NKN 295
KN
Sbjct: 358 KKN 360
Score = 35.5 bits (78), Expect = 2.6
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Query: 362 ERRQSILQVAWLDADTGQERVLWREIDKLSRVVFPALFLLFVTMYW 407
+RR ++ ++ T Q+ W IDK R+VFP FL+F +YW
Sbjct: 465 QRRGTLARLNTFTTMTPQQIAQW--IDKRCRIVFPVSFLIFNILYW 508
>UniRef50_Q10052 Cluster: Gaba/glycine receptor family (See gbr)
protein 3; n=4; Caenorhabditis|Rep: Gaba/glycine
receptor family (See gbr) protein 3 - Caenorhabditis
elegans
Length = 438
Score = 142 bits (343), Expect = 2e-32
Identities = 85/303 (28%), Positives = 149/303 (49%), Gaps = 14/303 (4%)
Query: 11 VIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDN 70
V V + V D++SI+ F D++ Q W + RL+ + +++L +
Sbjct: 58 VQVSVELTVQDISSISEISSSFIADVWFSQVWYDPRLEYRNISCKT---NLSLDSYVSER 114
Query: 71 LWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSC 130
LW P+ F+NSK T++ + + +Y N TV + R+ C E +P+D Q C
Sbjct: 115 LWTPNVCFVNSKSTQVHKSPASNILLIIYPNGTVWLNYRVQVSAPCSFELSRFPIDAQEC 174
Query: 131 PIYIESFSYSNQKVRFRWSE-AGVTINP--ELKLLQYHIGQPLRLEETNGYMIDKDGNYS 187
+ ES+SY+ +VR W + A VT+ P + +L + + +N Y G +
Sbjct: 175 HLVFESYSYNIAEVRLNWQQWAPVTMPPPEDFRLPDFQFYNVTWGKTSNEYTA---GMWD 231
Query: 188 RLVV-----YFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
+L V ++RF+R G++++Q + P+ L V +SW +FW+D A+P R
Sbjct: 232 QLKVTFSQTFYRFKRLYGYYVLQMYLPTYLSVFISWIAFWIDTRALPARITLGVSSLMAL 291
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMP 302
F + ++P V++VKA+DLW C+ F+F +L E VV +DK ++ + +
Sbjct: 292 TFQFGNIVKNLPRVSFVKAIDLWFFVCVAFIFFSLVELAVVGFVDKITEIKRRSRRIKFQ 351
Query: 303 RII 305
R I
Sbjct: 352 RAI 354
>UniRef50_P34903 Cluster: Gamma-aminobutyric acid receptor subunit
alpha-3 precursor (GABA(A) receptor subunit alpha-3);
n=94; Euteleostomi|Rep: Gamma-aminobutyric acid receptor
subunit alpha-3 precursor (GABA(A) receptor subunit
alpha-3) - Homo sapiens (Human)
Length = 492
Score = 141 bits (342), Expect = 3e-32
Identities = 82/279 (29%), Positives = 135/279 (48%), Gaps = 8/279 (2%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V+ IYV ++ DM++ +D+F RQTW + RL+ F+ + L +W
Sbjct: 93 VKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLK-----FDGPMKILPLNNLLASKIW 147
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + L N T+ Y+ R+ C M + +PMD+ +CP+
Sbjct: 148 TPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPL 207
Query: 133 YIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD--GNYSRLV 190
S++Y+ +V + W+ G + E+ + Q L G I + G Y +
Sbjct: 208 KFGSYAYTTAEVVYSWT-LGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMT 266
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
+F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R R
Sbjct: 267 THFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 326
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
+P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 327 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365
Score = 35.5 bits (78), Expect = 2.6
Identities = 12/31 (38%), Positives = 21/31 (67%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLLLKTKA 416
++DK+SR++FP LF +F +YW + + A
Sbjct: 454 KVDKISRIIFPVLFAIFNLVYWATYVNRESA 484
>UniRef50_Q9NA62 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 434
Score = 141 bits (341), Expect = 4e-32
Identities = 78/294 (26%), Positives = 138/294 (46%), Gaps = 7/294 (2%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
PV VE I + D++ I+ F +D +I W++ RL + +++L +
Sbjct: 77 PVKVEVEITIQDISDISAITGTFTIDYWISAIWNDKRLAFSH--LDPCRKNLSLDHDMEP 134
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
LW P+ +NSK T++ + + ++ N T+ + R+ + CQM + +P+D
Sbjct: 135 KLWSPNVCIVNSKSTKVHDSPKPNILLMIFPNGTIWLNYRIRSEAPCQMNLRNFPLDSIR 194
Query: 130 CPIYIESFSYSNQKVRFRWSEAGV--TINPELKLLQYHIGQPLRLEETNGYMIDKDGNYS 187
C + ES+SY+ V +W E T+ + L + + T Y G +
Sbjct: 195 CSLVFESYSYNAADVELQWLEWSPVSTVRNDYNLPDFRMTNITYGSVTEAYTA---GMWH 251
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
RL V FER G +++Q + P+ + V +SW +FW+D A+P R F
Sbjct: 252 RLSVSIHFERLYGFYILQMYLPTYISVFISWIAFWMDTKALPARITLSVSSLMALTFQFG 311
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESM 301
+ +P +YVKA+D+WM C+ F+F +L E +V DK + + + S+
Sbjct: 312 NIVKSLPKASYVKAIDIWMFSCVGFIFFSLIELAIVAYNDKMHDQRLREVRCSV 365
>UniRef50_A7SAV3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 373
Score = 140 bits (340), Expect = 5e-32
Identities = 102/391 (26%), Positives = 176/391 (45%), Gaps = 27/391 (6%)
Query: 31 DFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELT 90
DF + ++ RQ W +SRL D++ D VT+ + +W PD +F K +
Sbjct: 1 DFSMTIYFRQWWRDSRLAYG-DMYHR--DSVTIGGDILKQIWLPDTHFEYEKKPKDRTRD 57
Query: 91 HKFSSVTLYRNQTVRYSARM---HAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFR 147
H F + L+R+ T+ +S R C M+ + YPMD Q C IESF Y V ++
Sbjct: 58 HVFL-LKLWRDGTIMWSRRQVIDSITTTCAMDLRSYPMDTQRCNFSIESFGYPINDVVYK 116
Query: 148 W----SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHL 203
W S+ + + +L L ++ + + + + Y+ G++S +V F R+ +++
Sbjct: 117 WRLGRSDEDIKVKQDLALTKFTLWKIQTFTKISHYVT---GSFSGIVAEFTMTRRALYYV 173
Query: 204 IQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALD 263
IQ F P +++V LSW SFW+D + P R G+++ +P V YVK+LD
Sbjct: 174 IQIFLPCAMIVFLSWISFWIDSHSTPARIALGITTVLSMTTLLFGVQSSLPKVPYVKSLD 233
Query: 264 LWMAGCMMFVFAALGEFVVVKV-LDKQYQMNKNKAQESMPRIIPVRLNGDKGSCGTIAAW 322
++M VFA+L E+ V + K+ + AQ+ + + G+K + +
Sbjct: 234 VYMFVSFTLVFASLIEYACVHYNITKKDRAVFQVAQQQKQTHME-KATGNKETVRLLRRM 292
Query: 323 EGSGVRCRKVDIXXXXXXXXXXXXXXXXXXXXXXXXXGVERRQSILQVAWLDADTG-QER 381
+G + + V S L + +D R
Sbjct: 293 KGQSMNFK--------MAAFGRLGPTSKSSTEAAAWSAVNLVPSALDGKSVPSDENLVPR 344
Query: 382 VLWREIDKLSRVVFPALFLLFVTMYWPVLLL 412
V +D+ SRV+FP+ FL+F +YWP+ +L
Sbjct: 345 V--NLVDRYSRVLFPSFFLVFNIIYWPIYML 373
>UniRef50_A7SCG4 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 270
Score = 139 bits (336), Expect = 1e-31
Identities = 82/265 (30%), Positives = 131/265 (49%), Gaps = 12/265 (4%)
Query: 31 DFRVDMFIRQTWSESRLQLPED-IFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAEL 89
DF + ++RQ W + L+ + ++ + + L +NLW PD Y N K E+
Sbjct: 1 DFSFEFYMRQRWIDPTLKYNKSSLYNKNYSYAILDHTLVNNLWKPDTYIENLKRLEMGFS 60
Query: 90 THKF--SSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFR 147
F + L+ N V S+R+ A ++C M F +PMD QSC + I S+ ++ + +
Sbjct: 61 GGPFINEGLRLFPNGLVLISSRVSATLSCAMNFHNFPMDRQSCSVTISSYFFTEDDLYYD 120
Query: 148 WSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTF 207
W++ + L Q+ + L L+ ++ G YS LV FRF R+I ++L+ +
Sbjct: 121 WNDVSIYKG---NLSQFDL---LGLDSLRKSLVFTSGTYSSLVATFRFRRRIQNYLLSFY 174
Query: 208 APSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMA 267
P+ L VMLSW SF++ ++ P R T R P V+YV + DL++
Sbjct: 175 VPTILTVMLSWVSFFISPNSAPARCALGIITVLAVGGFLTNQRKSFPTVSYVMSADLYIL 234
Query: 268 GCMMFVFAALGEFVVVK---VLDKQ 289
C +FVF AL E+ VV V DKQ
Sbjct: 235 VCYVFVFCALLEYAVVHFFFVYDKQ 259
>UniRef50_Q9TZI5 Cluster: Expulsion defective (Defecation) protein
1; n=6; Caenorhabditis|Rep: Expulsion defective
(Defecation) protein 1 - Caenorhabditis elegans
Length = 539
Score = 138 bits (335), Expect = 2e-31
Identities = 81/298 (27%), Positives = 145/298 (48%), Gaps = 13/298 (4%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVT 62
P KG+ VE S+ V ++ +++ MD+ +++F R++W + RLQ +F+ + +
Sbjct: 117 PENEKGEATYVEVSVVVSNIRAVSEVTMDYALELFYRESWRDPRLQYDRKLFKNKTE-LA 175
Query: 63 LPPEFFDNLWHPDPYFLN---SKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
L + + LW PD + N SK + ++H+ S + L + YS R+ + C M+
Sbjct: 176 LHESYTNFLWFPDTFVPNAIASKNPQRNSISHR-SLLRLDETGKLLYSRRISLVCECTMD 234
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINP--ELKLLQYHIGQPLRLEETNG 177
L+P D Q C + IES+ Y+ V ++WS+ T +++L + I + +
Sbjct: 235 LTLFPFDKQLCKLGIESYGYTADHVVYKWSKGARTALELKKIRLPDFTIQEAYVTSQMES 294
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
Y GNYSRL V F F R G +Q PS+ VV+ SW S W++ +
Sbjct: 295 YAT---GNYSRLYVCFVFSRSSGFCFLQLIIPSTAVVITSWVSLWMETET---EFQDMIS 348
Query: 238 XXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKN 295
+P V+Y+KA+D+++ C M VF +L + +VK + ++ + +
Sbjct: 349 IILAITFLIFSYNEMMPRVSYIKAMDIYLGVCFMIVFLSLIKLALVKYMRQKIMLTSD 406
>UniRef50_Q21005 Cluster: Putative uncharacterized protein acc-1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acc-1 - Caenorhabditis elegans
Length = 466
Score = 138 bits (335), Expect = 2e-31
Identities = 83/294 (28%), Positives = 146/294 (49%), Gaps = 8/294 (2%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
P V ++V +V S++ DF +D++I + W + L + ED+ +++ +
Sbjct: 54 PTHVRVDMWVQEVTSVSELTQDFEIDLYINEFWEDPAL-VYEDM-NPCKRNISFDDKVLQ 111
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
LW P+ F+NSK I E K + ++ N T+ + RM C M+ + +P D Q
Sbjct: 112 RLWLPNTCFINSKSAAIHESPFKNVFLMVFSNGTLWTNYRMKLTGPCDMKLKRFPFDKQK 171
Query: 130 CPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRL 189
C + ESF+Y+ +VR +W++ I LK ++ + + + G + L
Sbjct: 172 CYLTFESFNYNTGEVRMQWNQPYPVIL--LKRIELPDFKLVNFSVIAVEQMYPAGWWDEL 229
Query: 190 VVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGL 249
V F FER+ G +++Q + P+ + +++SW SF+L AIP R F +
Sbjct: 230 TVAFVFERRYGWYVLQGYIPTMVTIVISWISFYLGPRAIPARTMLGVNSLLAMTFQFGNI 289
Query: 250 RADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY----QMNKNKAQE 299
++P V+YVKA+D+WM M+F+F +L E VV + + ++ K K QE
Sbjct: 290 IRNLPRVSYVKAIDVWMLSGMLFIFLSLLELAVVGFMSRNEGLPPKVKKRKRQE 343
>UniRef50_Q8MM20 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 428
Score = 138 bits (333), Expect = 3e-31
Identities = 77/290 (26%), Positives = 140/290 (48%), Gaps = 5/290 (1%)
Query: 11 VIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDN 70
V V ++V +V S++ DF +D+++ + W++ L DI +++ N
Sbjct: 82 VDVRIEMWVQEVTSVSELTQDFEIDLYMNEYWTDPGLAY--DILNPCQGNLSFDWAVMQN 139
Query: 71 LWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSC 130
+W P+ F+NSK ++ + ++ N +V + R+ + C M+ +PMD C
Sbjct: 140 IWTPNTCFINSKKAQLHSSPFTNVFLMVFPNGSVWSNWRIKSTGPCVMDLTKFPMDSIEC 199
Query: 131 PIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLV 190
+ ESF+Y+ +V RW + +TI ++L + + +N + + G +S L
Sbjct: 200 TLTFESFNYNKDEVFMRWGDPPLTIFKPIELPDFTM---TNFSTSNKFQLYAAGYWSELN 256
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
V F F R+ G +L+Q + P+ + V +SW F+L AIP R F +
Sbjct: 257 VNFLFRRRSGWYLLQGYIPTYMTVFISWIPFYLGPKAIPARTMIGVNALLALTFQFGNII 316
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQES 300
++P V+Y+KA+D+WM + FVFA+L E + L + K+ S
Sbjct: 317 RNLPRVSYIKAIDVWMLSGICFVFASLFELATIGFLMRNEGKPATKSSRS 366
>UniRef50_A7RZG9 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 405
Score = 137 bits (331), Expect = 6e-31
Identities = 79/281 (28%), Positives = 137/281 (48%), Gaps = 9/281 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDI-FEEGDDHVT 62
P G+ V+V+ V+ I +M++ +D+F RQ W +SR + F D
Sbjct: 58 PNAGGEKVMVDIEFKVISFGEIKEANMEYSLDIFFRQWWYDSRFAHNYSMPFTMAAD--- 114
Query: 63 LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQL 122
P E F W PD YF N K +T + V + + + +SAR+ C+M+ L
Sbjct: 115 -PTELF---WTPDTYFWNVKSANYHRVTRENMRVMINPDGKIYFSARITLTCQCEMDLHL 170
Query: 123 YPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDK 182
YP+D Q CP+ IES++++ V +RW + G T E+ + L + +
Sbjct: 171 YPLDTQECPLRIESYAHTVADVDYRW-KGGETQGVEIVSEEMAQFDLLGVRTDTKKSTNS 229
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G ++ L FRF R++ +L + P ++V+LSW +F++ A+P R
Sbjct: 230 KGAFASLKATFRFRRRMDFYLSSIYVPEVILVVLSWTTFFITPSAVPARTALSITTILTT 289
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ + + +P V+Y+K++D +M F+FAAL E+++V
Sbjct: 290 ILLSSSVNSGMPKVSYMKSIDHFMLISFGFIFAALIEYIIV 330
>UniRef50_Q17KW1 Cluster: Glycine receptor beta, putative; n=1;
Aedes aegypti|Rep: Glycine receptor beta, putative -
Aedes aegypti (Yellowfever mosquito)
Length = 439
Score = 136 bits (330), Expect = 8e-31
Identities = 73/277 (26%), Positives = 134/277 (48%), Gaps = 8/277 (2%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V S+Y+ ++ ++ + +D F++ TW + RL + +++ L P +W
Sbjct: 13 VSISLYINRISGVDENKEEISIDAFLQVTWEDPRLVPDDPTGTMTKEYMELTPTEQMTVW 72
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD Y + ++ L + S + LY+N T+ + I C M+F LYP+D+Q CP+
Sbjct: 73 VPDLYIRQLREMKVMTLFEEISKLRLYKNSTLVLTKGATIIFKCDMDFVLYPLDVQRCPV 132
Query: 133 YIESFSYSNQKVRFRWSEAGVTINPE------LKLLQYHIGQPLRLEETNGYMIDKDGNY 186
S+ YS +++RFRW I P+ +L +Y + E+ + + N+
Sbjct: 133 DFSSYKYSVREMRFRWKNDNGLIFPKDFGDGFFRLPKYVVS--FYTEQNPQTIHYGEDNH 190
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
S + R++ +L++ + PS+L V +SW SF + + +PGR F
Sbjct: 191 SSARLEITLSREVKSYLLENYLPSTLFVSMSWGSFVVVPEIVPGRMVLLVTTLLSLITMF 250
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+R + P +K L++W+ C +FVF AL E+ +V
Sbjct: 251 DTVRNNSPDALELKCLEVWLISCTLFVFFALMEYFIV 287
>UniRef50_Q9TVI7 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 538
Score = 136 bits (328), Expect = 1e-30
Identities = 78/294 (26%), Positives = 142/294 (48%), Gaps = 7/294 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG V VE + + V+ I+ + + Q W + L + +++L
Sbjct: 105 PKMKGVDVDVE--LLIQRVSEISEIQSSSTMHILFSQIWHDPGLSFEHEEGAHCLTNLSL 162
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
DN+W P+ +NSK + I + + ++ N TV + R+ C+M+F +
Sbjct: 163 SHRMVDNIWLPNVCIVNSKGSAIHKSPTPNIFLAIFPNGTVWMNYRVVVESPCEMDFSFF 222
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMID 181
PMD C ES++++ KVR W G + ++KL +H+ + + + T I
Sbjct: 223 PMDRVMCTTIFESYAFNVGKVRLHWKRQGQPVEFIDDVKLPDFHMTKFVHEKAT---FIY 279
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
G + +L + F R G +++Q + P+ +V++SW SFWLD ++P R
Sbjct: 280 PAGVWDQLNIKLLFRRSYGFYILQIYLPTYCMVLISWISFWLDRRSLPARVTLGVSSLMA 339
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKN 295
++ + +P V+YVK LDL+M GC++++F ++ E VV L+++ Q N
Sbjct: 340 LTLQYSNVSRSLPKVSYVKGLDLFMFGCIVYIFLSIVELAVVGSLEQRKQQRTN 393
>UniRef50_UPI0000D56CB6 Cluster: PREDICTED: similar to CG6927-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG6927-PA - Tribolium castaneum
Length = 464
Score = 135 bits (326), Expect = 2e-30
Identities = 82/282 (29%), Positives = 137/282 (48%), Gaps = 13/282 (4%)
Query: 15 FSIYV-VDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFD-NLW 72
F + V VD+N + F M ++ T+ +S L+ EDI + + L E +W
Sbjct: 62 FGVIVNVDINHLEASQSQFTAYMTVKCTYLDSNLKF-EDISPKRS--LILGDETLKAKIW 118
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
P+ + + T I ++ K V++ + V Y+ +M + C M+ + +P D Q C +
Sbjct: 119 TPNILLKDQEETTIVQVEKKEDLVSIDKTGLVIYTYKMVSKFYCWMDLKKFPFDTQKCTL 178
Query: 133 YIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNG--Y----MIDKDG 184
+SY++ + W++ ++N L ++ + + TN Y M D+ G
Sbjct: 179 IFSDWSYNSTNLLLEWNKKSESLNVSDNLHFTEFIVDEIKCDTGTNDGPYQNRDMSDQVG 238
Query: 185 NYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXX 244
++S LV+ FRF R IG++L+ F PS L+V +W +FWL DA P R
Sbjct: 239 SFSELVIKFRFHRDIGYYLLDFFIPSYLLVCTAWVTFWLQADAGPPRATLGATTVVAFIT 298
Query: 245 XFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
G+ DIP V+Y+KA D+W G F+F +L EF V V+
Sbjct: 299 LHLGMSKDIPKVSYIKASDIWFLGVSCFIFFSLAEFAFVNVI 340
>UniRef50_A7SDF0 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 349
Score = 134 bits (323), Expect = 5e-30
Identities = 89/270 (32%), Positives = 138/270 (51%), Gaps = 20/270 (7%)
Query: 37 FIRQTWSESRL--QLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFS 94
+ RQ W + RL +L + + +GD+ +W PDP+ N++ + + +
Sbjct: 1 YFRQFWKDERLANRLNKSVVLKGDE--------ITKMWRPDPFCYNARESSLTASDDDIN 52
Query: 95 SV-TLYRNQTVRYSARMHAIIA-CQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRW-SEA 151
S+ T++ N V YS RM I A C+M+ +PMD Q C + + S+SYS + + +RW S
Sbjct: 53 SMMTIHPNGDVVYS-RMTIITAECEMKLHDFPMDEQQCHLKLGSYSYSTKNIVYRWQSPL 111
Query: 152 GVTI-NPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPS 210
GVT+ N L + + EE G M GNYS L V F F+R++G+ LIQ +AP
Sbjct: 112 GVTVRNKNLAQFIFTYLELSEYEEIYGMM----GNYSILQVDFAFKRRLGYFLIQVYAPD 167
Query: 211 SLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCM 270
VV+LSW FW+D D + R + A +P V+Y KALD ++
Sbjct: 168 IFVVLLSWIVFWMDKDDMGNRMALGITTILTIMFLLGSVNAAMPRVSYPKALDWYLMVSF 227
Query: 271 MFVFAALGEFVVVKVLDKQYQMNKNKAQES 300
VF L E ++V V+ K Y+ ++ K + S
Sbjct: 228 SLVFLVLIECMIVFVISK-YKNDRRKRRIS 256
Score = 34.7 bits (76), Expect = 4.6
Identities = 11/26 (42%), Positives = 20/26 (76%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
++DK +R+VFP +F++F +YW + L
Sbjct: 321 DVDKFARIVFPMVFIVFNILYWCIYL 346
>UniRef50_P41849 Cluster: Uncharacterized glycine receptor-like
protein T20B12.9; n=2; Caenorhabditis|Rep:
Uncharacterized glycine receptor-like protein T20B12.9 -
Caenorhabditis elegans
Length = 476
Score = 132 bits (320), Expect = 1e-29
Identities = 76/286 (26%), Positives = 140/286 (48%), Gaps = 8/286 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P +G V +E ++V V+ I+ DF +D+ + W + RL ++TL
Sbjct: 33 PEAEGVNVTIE--LHVQGVSGISEITGDFSLDVMYSEIWQDPRLSFKH--LNVCATNITL 88
Query: 64 P-PEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQL 122
+F +W PD +NSK + I + + V LY N V + R++ C + ++
Sbjct: 89 KVSDFRKKIWTPDTCIINSKSSSIHSSPSENTFVILYENGLVWSNFRLNVKTPCSVNLKM 148
Query: 123 YPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDK 182
+P D SC I +ES+S++ +VR W + +T+ +++L + + + + +
Sbjct: 149 FPFDSLSCEIVLESYSFNTDEVRLMWHDVPITMMEKVELPDFDL---IGWSTDHQRLEYP 205
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
+G + R V F F R+ G +L Q++ P+SL V+ SW F+ D+ ++ R
Sbjct: 206 NGIWDRAKVKFTFARRYGFYLFQSYFPTSLTVISSWVGFFFDVRSVSARITLGVSSLLAL 265
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDK 288
F + +P V+Y+K LD+WM ++F+F L E +V L++
Sbjct: 266 TFQFGNVLRHLPRVSYIKCLDVWMIFSVIFIFCTLVELAIVCQLNR 311
>UniRef50_A7SDF1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 273
Score = 132 bits (318), Expect = 2e-29
Identities = 74/267 (27%), Positives = 128/267 (47%), Gaps = 10/267 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP G P ++ +YV +I +M+++V F RQ W E RL + +
Sbjct: 16 LRPGDGDG-PTLITADLYVSSFGNIQETNMEYKVFGFFRQYWREDRLA------GKHNKT 68
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSS-VTLYRNQTVRYSARMHAIIACQME 119
V L + DN+W PDP+ N++ + + E SS V L + +V YS + C M
Sbjct: 69 VILTGKEIDNMWKPDPFCNNARESNLRETDESISSMVFLEPDGSVLYSRLIIVTAECNMN 128
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+ +PMD Q C + + S+SY+ + + ++W + K L + + +
Sbjct: 129 LRFFPMDEQKCYLKLSSYSYTTENIIYKWKTGKPAVEVGTKDLAQFDMKTVEISNMTDTF 188
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
+ G++ ++V F F+R++G+ +IQ FAP VVMLSW FW+D + + R
Sbjct: 189 VT--GDFEAIIVTFTFKRRLGYFIIQVFAPDIFVVMLSWIVFWMDREDMGNRMALGITII 246
Query: 240 XXXXXXFTGLRADIPPVAYVKALDLWM 266
+ + +P V+Y KALD ++
Sbjct: 247 LTIMFLLGAINSSMPRVSYPKALDWYL 273
>UniRef50_A7RTF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 291
Score = 132 bits (318), Expect = 2e-29
Identities = 72/284 (25%), Positives = 138/284 (48%), Gaps = 19/284 (6%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G+P V+ ++Y + IN M++ + RQ W + RL + I E +
Sbjct: 19 PGLGGKPCRVKVNLYFMSFAPINEPQMEYTPTFYFRQYWQDPRLAFGDSIRAEA---IRP 75
Query: 64 PPEFFDNLWHPDPYFLNS---KVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+F +W PD +F++ V + + S+ + N+ R+ R C M F
Sbjct: 76 RGDFTKKIWTPDTFFIDDVTDNVRRVDSMLEISSNGSFNTNRFFRWRIRSF----CPMTF 131
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSE--AGVTINPELKLLQYHIGQPLRLEETNGY 178
+P D+Q C SFSY+++ + + W + + + +L++ Y + +E +
Sbjct: 132 TRFPFDVQRCSFTFSSFSYNDKDLVYEWMKNPPALEFSSQLRMAHYDL-----IEWSTES 186
Query: 179 MIDK--DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXX 236
+D+ G Y+ L F F+R++ +++ F P++ +V+LSW FW+D ++P R
Sbjct: 187 KLDEFVTGKYASLTAKFVFKRRVRFYILSAFIPAAFIVILSWVGFWIDERSVPARVSLGI 246
Query: 237 XXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEF 280
G+++ +P V Y+KA+D+++ G +FVFA+L E+
Sbjct: 247 TTVLAITTLIFGVQSTLPRVGYIKAIDVYLLGNFLFVFASLVEY 290
>UniRef50_Q0GQQ6 Cluster: Cys-loop ligand-gated ion channel subunit;
n=3; Endopterygota|Rep: Cys-loop ligand-gated ion
channel subunit - Apis mellifera (Honeybee)
Length = 510
Score = 131 bits (317), Expect = 3e-29
Identities = 83/289 (28%), Positives = 132/289 (45%), Gaps = 12/289 (4%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVT 62
P KG P +V+ +I + + ++ DMD+ +D + RQ+W +SRL I ++
Sbjct: 54 PTHGKGTPTVVKTNILIRSMGPVSELDMDYSMDCYFRQSWRDSRLSFLGPI-----KSLS 108
Query: 63 LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQL 122
L + + +W PD YF N K + + +T + + ++ + YS R+ C ME +
Sbjct: 109 LSIKMLERIWRPDTYFYNGKHSYVHTITVPNKLLRISQDGDILYSMRLTIKAKCPMELRN 168
Query: 123 YPMDIQSCPIYIESFS--YSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYM 179
+PMD QSCP+ + S Y + P + L Q+ + G P R N
Sbjct: 169 FPMDRQSCPLILGSCKCIYVQSINLCMAGRLFGYLCPGMALSQFDLMGSPYR----NLTF 224
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
+ ++G +S L V F +R G+ LIQ + P L+V+LSW SFW+ +A R
Sbjct: 225 VRREGEFSVLQVSFNLQRHTGYFLIQVYVPCVLIVVLSWVSFWIHREATSDRVGLGITTV 284
Query: 240 XXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDK 288
R D+P V Y ALD ++ + A L EF V K
Sbjct: 285 LTLSTISLDSRTDLPKVRYATALDWFLLMSFGYCIATLLEFAGVHYFTK 333
>UniRef50_UPI00006A0B5C Cluster: Gamma-aminobutyric-acid receptor
subunit alpha-3 precursor (GABA(A) receptor subunit
alpha-3).; n=2; Xenopus tropicalis|Rep:
Gamma-aminobutyric-acid receptor subunit alpha-3
precursor (GABA(A) receptor subunit alpha-3). - Xenopus
tropicalis
Length = 465
Score = 130 bits (315), Expect = 5e-29
Identities = 75/268 (27%), Positives = 121/268 (45%), Gaps = 5/268 (1%)
Query: 22 VNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNS 81
V +N+ +++ +D+F RQ+W + RL+ F+ + L +W PD +F N
Sbjct: 76 VKQVNMPSLEYTIDVFFRQSWLDERLK-----FDGPIRTLPLNNLLASKIWTPDTFFHNG 130
Query: 82 KVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSN 141
K + +T + L N T+ Y+ R+ C M + +PMD+ +CP+ S Y N
Sbjct: 131 KKSVAHNMTTPNKLLRLIDNGTLLYTMRLTIHAECTMHLEDFPMDVHACPLKFGSCMYCN 190
Query: 142 QKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGH 201
++V F L Y + G Y + +F +R+IG+
Sbjct: 191 EQVSFYCHIDSDFPGQVAVHLHYFFSIITYYSAISSNCCSSLGEYIVMTTHFHLKRKIGY 250
Query: 202 HLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKA 261
+IQT+ P + V+LS SFWL+ +++P R R +P VAY A
Sbjct: 251 FVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATA 310
Query: 262 LDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
+D +MA C FVF+AL EF V K+
Sbjct: 311 MDWFMAVCYAFVFSALIEFATVNYFTKR 338
Score = 35.5 bits (78), Expect = 2.6
Identities = 13/21 (61%), Positives = 17/21 (80%)
Query: 387 IDKLSRVVFPALFLLFVTMYW 407
IDK+SR+VFP LF +F +YW
Sbjct: 440 IDKISRIVFPVLFAIFNLVYW 460
>UniRef50_Q9U358 Cluster: Putative uncharacterized protein acc-4;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acc-4 - Caenorhabditis elegans
Length = 408
Score = 129 bits (311), Expect = 2e-28
Identities = 73/296 (24%), Positives = 143/296 (48%), Gaps = 11/296 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLP-PE 66
G V+V I+V +V+ I +F +D+++ + W++ L ++++
Sbjct: 71 GGHVVVSIEIWVQEVSKIIEITSEFELDIYVTERWTDPSLAYSH--LNPCKSNMSVDGAT 128
Query: 67 FFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMD 126
+ +W+P F+NSK+ I E K + +Y N ++ ++ R+ C + +P+D
Sbjct: 129 ILNKIWNPHACFVNSKLANIHESPFKNIFLQIYSNGSIWHNYRIKLTGPCSSTLRTFPID 188
Query: 127 IQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQP----LRLEETNGYMIDK 182
Q C ++ ESF+++ +V+ W +T P + +L+ +I P + ++ +
Sbjct: 189 QQRCMLFYESFTHNTDQVKMEW----ITTVPPITILKGNITLPDYVLVDFSSSSELRLYP 244
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G ++ L+ F F+R G +++Q + P+ + V +SW SF L + IP R
Sbjct: 245 PGIFNELIATFTFQRLYGFYILQVYVPAYISVFISWVSFTLGAEQIPSRTTVGVNSLLAL 304
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQ 298
F + ++P + VKA+D+W+ M F+FA+L E VV L + Q K +
Sbjct: 305 TFQFGAVVNNLPKTSDVKAIDVWILSSMAFIFASLIELAVVGYLSRDGQHGSIKCR 360
>UniRef50_A7S5Y7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 304
Score = 128 bits (310), Expect = 2e-28
Identities = 80/285 (28%), Positives = 135/285 (47%), Gaps = 16/285 (5%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQ--LPEDI-FEEGDDH 60
P +G PV + I V ++ DM F +DMF RQ+W + RL+ + E + G H
Sbjct: 17 PNYQGDPVEILIDISVASFGNLQEADMKFSLDMFFRQSWHDPRLRHNMNETMTLTTGTKH 76
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
P +F +W PD F+++ + + + + V + R I C M
Sbjct: 77 ---PADF---VWVPDTVFVDASHAYMHNVMVANHKLDVTPGGRVFWGTRATLIARCHMNL 130
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQ--PLRLEETNGY 178
+ YPMD Q+C + I S++Y + + +RW + P +K+L + Q R+ +
Sbjct: 131 RRYPMDEQTCNLSIISYAYPVRHLLYRWKNS-----PGIKVLDGEMSQFYMTRITTSLRN 185
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
I G YS L F F+R++G +LIQ + P +V ++W S W+D A P R
Sbjct: 186 EIYVAGEYSVLKASFTFQRRVGFYLIQIYIPCMAIVFVAWMSLWVDRRATPARVSLCITT 245
Query: 239 XXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ + A +P V+YVK++D+++ FV L E++V+
Sbjct: 246 LLTIATIWGNVNASMPRVSYVKSIDIYLMTSFTFVLGTLLEYIVI 290
>UniRef50_A7RF65 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 290
Score = 128 bits (309), Expect = 3e-28
Identities = 77/260 (29%), Positives = 129/260 (49%), Gaps = 13/260 (5%)
Query: 25 INVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVT 84
I ++MDF +++++ QTW + RL D + L EF ++W PD L +
Sbjct: 43 IREKEMDFSLEVYLNQTWHDDRLN------HTLDHPIILSGEFKGSVWQPDTIILYVRSL 96
Query: 85 EIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYS-NQK 143
+ + SS+T+Y + TVR + R+ +I C M+ + YP+D Q C + + S + + N
Sbjct: 97 TVYNSLSEPSSITIYSDGTVRSTVRLALVINCLMDLRDYPLDEQECSLAMLSCNLTVNSH 156
Query: 144 VRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHL 203
++ + + L + I + + L N + GN+SR+ F F+RQI + L
Sbjct: 157 NNYKMLVV-IAFFSTVVLPRISIYKSMSL---NSVLFV--GNWSRVTTTFLFKRQIEYAL 210
Query: 204 IQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALD 263
+Q +AP+ L+V LSW SFW+ +A+P R R P V+Y+KA+D
Sbjct: 211 LQIYAPTMLIVSLSWLSFWISKEAVPARVTLGVTTILTIVTLIGSFRFQFPKVSYIKAID 270
Query: 264 LWMAGCMMFVFAALGEFVVV 283
+ +FVF A EF+ V
Sbjct: 271 WFFIVSFVFVFGAQIEFIAV 290
>UniRef50_Q95QT7 Cluster: Glutamate-gated chloride channel protein
4; n=2; Caenorhabditis|Rep: Glutamate-gated chloride
channel protein 4 - Caenorhabditis elegans
Length = 500
Score = 128 bits (308), Expect = 4e-28
Identities = 79/300 (26%), Positives = 137/300 (45%), Gaps = 15/300 (5%)
Query: 11 VIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF-- 68
V+V S+ + +++++ ++M+F RQ W + RL+ E D+ EF
Sbjct: 74 VMVTTSLNIRSISAVSEKNMEFVAQFRFRQEWYDDRLRFIEHQGLLSSDYRNF--EFIHV 131
Query: 69 ---DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPM 125
+LW PD +F N K L + + + + + Y R+ +AC M YPM
Sbjct: 132 ARDQSLWIPDTFFQNEKNGWYHMLNQENRFLKIRSDGKLIYDRRLTLHLACSMHLSRYPM 191
Query: 126 DIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELK--LLQYHIGQPLRLEETNGYMIDKD 183
D Q+C I S++Y+ + + W + I+ L + I T+
Sbjct: 192 DHQNCEIAFASYAYTTADIEYIWDVPAIQIHEGANGALPNFEIASFKNASCTSK---TNT 248
Query: 184 GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXX 243
G YS L V R R L+Q + PSS++V ++W S+W+D + R
Sbjct: 249 GTYSCLKVEIRLNRVFSFFLLQLYIPSSMLVGVAWVSYWIDWKSTAARVPLAIVTLLTMI 308
Query: 244 XXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVK---VLDKQYQMNKNKAQES 300
+ +++PPV+Y K++D+W+ C++F+F +L E+ VV +LD+ QM K S
Sbjct: 309 TTSHAINSNLPPVSYAKSIDIWVGACVVFIFFSLIEYAVVNYVGILDEHRQMKKAACNRS 368
>UniRef50_UPI000065FF28 Cluster: Gamma-aminobutyric-acid receptor
subunit rho-1 precursor (GABA(A) receptor subunit
rho-1).; n=1; Takifugu rubripes|Rep:
Gamma-aminobutyric-acid receptor subunit rho-1 precursor
(GABA(A) receptor subunit rho-1). - Takifugu rubripes
Length = 477
Score = 127 bits (307), Expect = 5e-28
Identities = 69/230 (30%), Positives = 120/230 (52%), Gaps = 8/230 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
PA G + V + V ++SI+ DMDF + +++R W + RL + +T
Sbjct: 73 PAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFRSST----NKSMTF 128
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F++SK + I + T + ++ + V YS R+ AC M+F +
Sbjct: 129 DGRLVKKIWVPDVFFVHSKRSFIHDTTTDNIMLRVFPDGHVLYSLRVTVTAACNMDFSRF 188
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMID 181
P+D Q+C + +ES++Y+++ + W + ++I+ + L Q+ I Q +
Sbjct: 189 PLDTQTCTLELESYAYTDEDLMLYWKSGDESLSIDDRISLSQFLI-QKFHTTSRLAF-YS 246
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGR 231
G Y+RL + F R I L+QT+ P++L+VMLSW SFW+D A+P R
Sbjct: 247 STGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPAR 296
>UniRef50_Q0GQQ4 Cluster: Cys-loop ligand-gated ion channel subunit;
n=2; Apis mellifera|Rep: Cys-loop ligand-gated ion
channel subunit - Apis mellifera (Honeybee)
Length = 469
Score = 127 bits (306), Expect = 6e-28
Identities = 73/293 (24%), Positives = 135/293 (46%), Gaps = 10/293 (3%)
Query: 2 RPPARKGQ--PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDD 59
RPP P+ V Y+ + S + + F V M ++ + ++RL+ +
Sbjct: 28 RPPGEINSINPINVYTKAYIYTIKSNMAKTLQFDVHMMLQFRYLDARLKFSN--IAPYLN 85
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ D +W P Y N + I K V++ + VR + R+ A + C +
Sbjct: 86 QIYGGQFVRDLIWTPTVYVSNEPSSAITGNNVKDVLVSIDPSGMVRLNTRLQATLNCGLR 145
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI------GQPLRLE 173
+ +P D+Q CP+ ES++++ + W + + + EL L +Y + +
Sbjct: 146 LEKFPFDVQECPLIFESWTHNVLDMVLYWDQEPIILADELHLTEYKLVEKWVNSSEIFYT 205
Query: 174 ETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXX 233
+ Y GN+S + + F+ R++G ++ + PS L+V++SW SFWL +DA P R
Sbjct: 206 TSQQYYGHFAGNFSSISITFKLAREMGFFMMDYYIPSILIVVISWVSFWLHMDASPPRIV 265
Query: 234 XXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
+ + +P V+Y+KA ++W GC +F+FAA+ EF V +
Sbjct: 266 LGTNTILTFMTLASKVENSLPKVSYIKASEIWFLGCTIFLFAAMVEFAFVNTI 318
Score = 37.5 bits (83), Expect = 0.65
Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Query: 363 RRQSILQVAWLDADTGQERVLWREIDKLSRVVFPALFLLFVTMYW 407
RR ++ Q+ T QE W ID+ SR+VFP F++F +YW
Sbjct: 422 RRATLAQLHNFTTMTPQEIAQW--IDRRSRIVFPVAFIIFNILYW 464
>UniRef50_Q4SC79 Cluster: Chromosome undetermined SCAF14659, whole
genome shotgun sequence; n=2; Euteleostomi|Rep:
Chromosome undetermined SCAF14659, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 481
Score = 126 bits (304), Expect = 1e-27
Identities = 87/312 (27%), Positives = 148/312 (47%), Gaps = 42/312 (13%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G PV V +I V ++ I+ +M++ + +F+RQ+W + RL + + + L
Sbjct: 45 PGIGGPPVNVAMAIEVASIDHISEANMEYTMTVFLRQSWHDDRLS-----YNHTNKTLGL 99
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
F D LW PD + +N+K ++T + + L N + YS+R+ + +AC M+ Y
Sbjct: 100 DSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPNGVILYSSRITSTVACDMDLTKY 159
Query: 124 PM-------DIQSCP-------------IYIESF-------------SYSNQKVRFRWSE 150
PM D++SC I+I S YS++ + + WSE
Sbjct: 160 PMDEQECRLDLESCKSTSSNTFALLAPFIFIPSNHTALEKHHCVFVDGYSSEDIVYHWSE 219
Query: 151 AGVTIN--PELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFA 208
+ ++ +L+L Q+ I R + T G + RL + F+ R G ++IQ++
Sbjct: 220 SQQHVHGLDKLELSQFTITD-YRFD-TEMMNFKSAGRFPRLSLCFQLRRNRGVYIIQSYM 277
Query: 209 PSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAG 268
PS L+V +SW SFW+ A+P R R+ +P + +KALD++
Sbjct: 278 PSILLVAMSWVSFWISQSAVPARVTLGITTVLTMTTLMVSARSSLPRASAIKALDVYFWI 337
Query: 269 CMMFVFAALGEF 280
C +FVFAAL E+
Sbjct: 338 CYVFVFAALIEY 349
>UniRef50_A7RTF8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 262
Score = 126 bits (304), Expect = 1e-27
Identities = 75/256 (29%), Positives = 129/256 (50%), Gaps = 16/256 (6%)
Query: 32 FRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTH 91
F F+RQ W++ RL ++++ + +TL + +W PD Y N K + + E +
Sbjct: 1 FETTFFLRQLWTDPRLAYGH-VYKKRN--LTLGGDIMKQIWKPDTYINNEKSSTVPE--N 55
Query: 92 KFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWS-- 149
+F +T+ V YS RM + +C M + YPMD QSC I ES+ +N + W
Sbjct: 56 QFL-LTIDPEGRVVYSQRMTVVASCMMYLRNYPMDTQSCSISFESYGMNNDDLLLSWKAD 114
Query: 150 -----EAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLI 204
+ V I+ L + Q+ + + +ET Y G ++ L + F R+ ++++
Sbjct: 115 PGDKYKNAVIISDNLTMSQFALDEYHASKETFTY---PTGTFTLLKLTFSIRRKKFYYVV 171
Query: 205 QTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDL 264
QT+ P+ L+V+LSW SFW+ + P R G+++ +P V+YVKA+D
Sbjct: 172 QTYIPTILIVILSWVSFWIPRSSPPARVALGITTVLALTTLIFGIQSSMPRVSYVKAIDW 231
Query: 265 WMAGCMMFVFAALGEF 280
++ +FVF AL E+
Sbjct: 232 FLMVSFLFVFCALIEY 247
>UniRef50_UPI0000D56CB7 Cluster: PREDICTED: similar to CG6927-PA;
n=2; Tribolium castaneum|Rep: PREDICTED: similar to
CG6927-PA - Tribolium castaneum
Length = 534
Score = 125 bits (302), Expect = 2e-27
Identities = 77/287 (26%), Positives = 131/287 (45%), Gaps = 9/287 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
PA +G P+ V I + + S + + F+ M ++ + +SRL+ +D+F + D +
Sbjct: 104 PATEG-PLPVYMQIDLTHIES--ADQLQFKAHMLVQYLYKDSRLRY-KDVFPQRGDLIG- 158
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W P N + + + K V + V YS RM A C M Q +
Sbjct: 159 EELLRSKIWVPHVMVRNERDARVMGIDGKDVFVLIKPTGDVVYSYRMTATFYCWMNLQKF 218
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNGYMIDK 182
P D Q C + +S++Y+ + W + V I L L ++ + L E +
Sbjct: 219 PFDTQDCYLRWDSWTYNTTNLILHWDKNNPVKIAKNLHLTEFVLSGSLPQETVVPASFNN 278
Query: 183 D---GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
GN+S LV F +R++G++++ F PS L+V SW +FWL DA R
Sbjct: 279 GAFVGNFSELVFKFTLKREVGYYVMDYFLPSILLVCTSWVTFWLQADASAPRVTLGTSTM 338
Query: 240 XXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
G+ ++P V+Y+KA ++W C F+F ++ EF V V+
Sbjct: 339 LAFITLNGGINKNLPKVSYIKASEIWFLACACFIFCSMAEFAFVNVI 385
>UniRef50_Q4SKT9 Cluster: Chromosome undetermined SCAF14565, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF14565, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 502
Score = 124 bits (300), Expect = 3e-27
Identities = 66/246 (26%), Positives = 122/246 (49%), Gaps = 9/246 (3%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V + V ++SI+ +MDF + +++R W + RL P + + T +W
Sbjct: 86 VGIDVQVESIDSISEVNMDFTMTLYLRHYWKDERLAFPS----QTNQSRTFDSRLVKKIW 141
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F++SK + I + T + + +Y + + +S R+ M+F ++P+D Q+C +
Sbjct: 142 VPDVFFVHSKRSFIHDTTMENIMLRVYPDGNILFSVRVTVTALRSMDFTIFPLDTQNCSL 201
Query: 133 YIESFSYSNQKVRFRWSEAGVTINP-ELKLLQYHIGQPLRLEETNGYMI-DKDGNYSRLV 190
+ES++Y+ + W ++ E+ L Q+ I Q + ++G G Y+RL
Sbjct: 202 ELESYAYNENDLMLYWKNGNDSLRTDEIVLSQFFIEQ---FQASSGLAFYSSTGWYNRLF 258
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
+ F R I ++QT+ P+ L+V+LSW SFW+D A+P R TG+
Sbjct: 259 ISFLLRRHIFFFMLQTYFPTMLMVVLSWVSFWIDRRAVPARVSLGITTVLTMSTIITGVS 318
Query: 251 ADIPPV 256
+ +P V
Sbjct: 319 SSMPQV 324
Score = 33.9 bits (74), Expect = 8.0
Identities = 14/21 (66%), Positives = 16/21 (76%)
Query: 387 IDKLSRVVFPALFLLFVTMYW 407
ID SRVVFP +LLF T+YW
Sbjct: 478 IDSYSRVVFPLSYLLFNTIYW 498
>UniRef50_Q9VUV2 Cluster: CG33989-PD, isoform D; n=2; Drosophila
melanogaster|Rep: CG33989-PD, isoform D - Drosophila
melanogaster (Fruit fly)
Length = 737
Score = 124 bits (298), Expect = 6e-27
Identities = 70/279 (25%), Positives = 134/279 (48%), Gaps = 10/279 (3%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V ++ ++ + S + + + V+ + Q W++ RLQ + + + D++W
Sbjct: 364 VNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNAL----HHHDSIW 419
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD YF+ + + F+ + ++RN T+ Y+ R H I++CQ ++P D C
Sbjct: 420 TPDTYFIMHGDFKDPIIPMHFA-LRIFRNGTITYAMRRHLILSCQGSLHIFPFDDPKCSF 478
Query: 133 YIESFSYSNQKVRFRWSEAGVTI--NPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLV 190
+ES SY ++++ W T+ +P L L ++ ++ + T GNYS L
Sbjct: 479 SMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYL---IKNQTTACDQNSWRGNYSCLQ 535
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
V F R ++ F P ++V S+ +FWL+ +A+P R G R
Sbjct: 536 VELTFTRDRAYYFTTVFIPGIILVTSSFITFWLEWNAVPARVMIGVTTMLNFFTTSNGFR 595
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
+ +P V+ + A+++W CM F++A+L EFV V + ++
Sbjct: 596 STLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRK 634
>UniRef50_Q2PDY9 Cluster: CG33989-PF, isoform F; n=16;
Endopterygota|Rep: CG33989-PF, isoform F - Drosophila
melanogaster (Fruit fly)
Length = 779
Score = 124 bits (298), Expect = 6e-27
Identities = 76/313 (24%), Positives = 147/313 (46%), Gaps = 18/313 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
R P +G + V ++ ++ + S + + + V+ + Q W++ RLQ + + +
Sbjct: 379 RRPHNRGT-LTVNVNVLLLSLASPDESSLKYEVEFLLNQQWNDPRLQYGNKSHYDFLNAL 437
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
D++W PD YF+ + + F+ + ++RN T+ Y+ R H I++CQ
Sbjct: 438 ----HHHDSIWTPDTYFIMHGDFKDPIIPMHFA-LRIFRNGTITYAMRRHLILSCQGSLH 492
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTI--NPELKLLQYHIGQPLRLEETNGYM 179
++P D C +ES SY ++++ W T+ +P L L ++ ++ + T
Sbjct: 493 IFPFDDPKCSFSMESISYEEAQIKYVWKNDEDTLRKSPSLTTLNAYL---IKNQTTACDQ 549
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
GNYS L V F R + F P ++V S+ +FWL+ +A+P R
Sbjct: 550 NSWRGNYSCLRVDLIFTRDRAFYFTTVFIPGIILVTSSFITFWLEWNAVPARSMIGVTTM 609
Query: 240 XXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ-------YQM 292
G R+ +P V+ + A+++W CM F++A+L EFV V + ++ Y+
Sbjct: 610 LNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFVCVNYVGRKRPLHNVVYRP 669
Query: 293 NKNKAQESMPRII 305
+N + +P ++
Sbjct: 670 GENPVTQRLPAVL 682
>UniRef50_UPI0000E20C28 Cluster: PREDICTED: gamma-aminobutyric acid
A receptor, alpha 6 isoform 1; n=1; Pan troglodytes|Rep:
PREDICTED: gamma-aminobutyric acid A receptor, alpha 6
isoform 1 - Pan troglodytes
Length = 478
Score = 123 bits (296), Expect = 1e-26
Identities = 89/335 (26%), Positives = 147/335 (43%), Gaps = 40/335 (11%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G V+ IYV ++ +M++ +D+F RQTW++ RL+ F + ++L
Sbjct: 49 PGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLK-----FGGPTEILSL 103
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F N K + +T + +N T+ Y+ R+ C M +
Sbjct: 104 NNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNF 163
Query: 124 PMDIQSCPIYIESFS-------------------------YSNQKVRFRWSEA---GVTI 155
PMD +CP+ S++ Y ++ + W + V +
Sbjct: 164 PMDGHACPLKFGSYNVHFEGKKDNSSNSLLYLICFKYLDAYPKSEIIYTWKKGPLYSVEV 223
Query: 156 NPELK-LLQYH-IGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLV 213
E LLQY IGQ + E G Y + VYF +R++G+ +IQ + P +
Sbjct: 224 PEESSSLLQYDLIGQTVSSETIKS----NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMT 279
Query: 214 VMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFV 273
V+LS SFW++ +++P R R +P V+Y A+D ++A C FV
Sbjct: 280 VILSQVSFWINKESVPARTVFGITTVLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFV 339
Query: 274 FAALGEFVVVKVL-DKQYQMNKNKAQESMPRIIPV 307
F+AL EF V + Q Q K KAQ + P + +
Sbjct: 340 FSALIEFAAVNYFTNLQTQKAKRKAQIAAPPSVTI 374
>UniRef50_Q9V9Y4 Cluster: CG11340-PA; n=2; Sophophora|Rep:
CG11340-PA - Drosophila melanogaster (Fruit fly)
Length = 526
Score = 122 bits (294), Expect = 2e-26
Identities = 72/284 (25%), Positives = 127/284 (44%), Gaps = 8/284 (2%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
P+ + Y+ + +++ D+ F V ++ + + RL + E
Sbjct: 102 PMDIYARFYIYVMKNLDSSDLQFTVQGLLQLRYLDPRLAF-SSYLPNRRQPIMGESELKK 160
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
LW P + N + + + + K ++Y N TV S R+ A + C M FQ +P D Q
Sbjct: 161 MLWVPHIFLTNEQASTVLGTSAKDELTSIYPNGTVLTSTRLQATLYCWMNFQKFPFDEQK 220
Query: 130 CPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLE----ETNGYMI--DK 182
C +ES+ Y+ V+ W ++ V+ + +L+L +Y++ L E YM
Sbjct: 221 CKTTLESWMYNTTLVQLHWETDNPVSFDKQLQLTEYNLIGSLYNESIRVSNESYMSHGSL 280
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
+GNYS + R++G+++I F PS ++V +SW SFWL D P R
Sbjct: 281 EGNYSIISFTVLLTREVGYYVIDYFLPSIMIVTISWVSFWLQADQTPARTTLGCTTLLSF 340
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
++ V+YV ++W C +F+F +L EF V +
Sbjct: 341 ITLSLSQENNLMKVSYVTMSEVWFLVCTIFIFGSLVEFAFVNTI 384
>UniRef50_Q9W4G1 Cluster: CG6927-PA; n=6; Diptera|Rep: CG6927-PA -
Drosophila melanogaster (Fruit fly)
Length = 524
Score = 120 bits (288), Expect = 9e-26
Identities = 70/284 (24%), Positives = 127/284 (44%), Gaps = 8/284 (2%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
PV V Y+ + ++ D+ F++ ++ + + RL ++ + + +
Sbjct: 66 PVDVYMRAYIYFMQNLEAHDLQFKIYALLQMRYLDPRLNF-RNVSPKRRQPILGEEHLRN 124
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
+LW P + N + + I LT K ++ + TV S R+ A + C + + +P D Q
Sbjct: 125 SLWMPHIFLANERDSSILGLTEKDILTSISPDGTVIVSNRIKATLYCWLNLKKFPFDEQH 184
Query: 130 CPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEET-NGYMIDKD---- 183
C +ES+ Y+ ++ W + +T + L L ++ + + E N + D
Sbjct: 185 CSTVLESWMYNTSELVLHWEQKRPITYDGALHLTEFVLQRSWSNETVINADLSDLRHGAF 244
Query: 184 -GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
GNYS L R +G +L+ F PS L+V +SW SFWL D P R
Sbjct: 245 AGNYSSLSFTVHLTRVVGFYLMDYFLPSMLIVAISWVSFWLQADQAPPRITLGTSTLLTF 304
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
+ +P V+Y+K ++W GC +F+F ++ EF V +
Sbjct: 305 ITLASAQGKTLPKVSYIKVSEVWFLGCTIFIFGSMVEFAFVNTI 348
>UniRef50_A7S6R3 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 409
Score = 119 bits (287), Expect = 1e-25
Identities = 82/259 (31%), Positives = 129/259 (49%), Gaps = 17/259 (6%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A K +P+ V SI V SI +M+F +F+RQ W++ RL D +
Sbjct: 60 RPNAGK-EPLDVYLSIGVQAFTSIKETNMEFTTSLFLRQEWTDIRLA------HGLDGTI 112
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+L + +W PD Y N+ E+ + ++ + ++ Y + V +SARM +CQM Q
Sbjct: 113 SLGGVEVNQIWRPDTYINNNNDYEL-HVENQLALISKYGD--VYFSARMLVRASCQMYLQ 169
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTI-NPELKLLQYHIGQPLRLEETNGYM 179
+PMD+Q C + ESF+Y+N V F W +TI N EL ++ + Q L +EE + M
Sbjct: 170 NFPMDVQKCSLVFESFAYTNDHVAFHWKGRNPITIFNKELS--EFDMEQWL-IEEVD--M 224
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
G Y L V F F R++G +LI + P ++V++SW FW+D +I R
Sbjct: 225 TYVAGKYRNLKVTFIFRRRLGFYLINFYVPCVVMVIMSWIVFWMDSSSIGERISLGITTI 284
Query: 240 XXXXXXFTGLRADIPPVAY 258
+ +P V+Y
Sbjct: 285 LTIVFLLGSSNSTMPRVSY 303
>UniRef50_O17041 Cluster: Putative uncharacterized protein T15B7.16;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T15B7.16 - Caenorhabditis elegans
Length = 435
Score = 119 bits (286), Expect = 2e-25
Identities = 82/303 (27%), Positives = 136/303 (44%), Gaps = 19/303 (6%)
Query: 11 VIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDN 70
V VEF I ++ ++ F +D+ Q W + RL+ D ++TL +
Sbjct: 59 VSVEFGIQ--NIAQVSEISASFTLDLLFSQIWHDPRLRF--DHLTNCLQNLTLGYSMVEK 114
Query: 71 LWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSC 130
LW P+ F+NSK TEI + +Y N TV + R+ C ++ L+PMDI +C
Sbjct: 115 LWTPNVCFVNSKKTEIHSSPTPNIFLMIYPNGTVWVNYRLQVQSPCMVDLVLFPMDIMNC 174
Query: 131 PIYIESFSYSNQKVRFRWSE-AGVTINPELKL--------------LQYHIGQPLRLEET 175
+ IES++Y+ KV+ W E V + KL +Y GQ ++
Sbjct: 175 ELIIESYAYNAAKVKLNWREWQPVFSIAKSKLSDFTLYGLQWTKNSFEYAAGQWDQVSSF 234
Query: 176 NGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXX 235
+ +L V F R G +++Q + P+ V LS+ SFW+DL A+P R
Sbjct: 235 CSLNCFSKMDGFQLTVSLTFSRAYGFYILQMYIPTYSSVFLSFVSFWIDLKALPARITLG 294
Query: 236 XXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKN 295
+ + ++P V YVK++D++M F+F + E V LD + + +
Sbjct: 295 VSSLMALTFQYGNVAKNLPRVGYVKSIDVYMVLTTAFIFLTMIEVAFVCYLDSENNLRRK 354
Query: 296 KAQ 298
+ Q
Sbjct: 355 ERQ 357
>UniRef50_A7SH22 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 239
Score = 119 bits (286), Expect = 2e-25
Identities = 63/216 (29%), Positives = 111/216 (51%), Gaps = 11/216 (5%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
P V+ YV +I +++F V M+ RQ W + RL + + V L +
Sbjct: 1 PTDVKLDFYVESFGNIEEANLEFSVFMYFRQMWRDPRLA------DRVNQSVVLQRDQIS 54
Query: 70 NLWHPDPYFLNSKVTEIAEL-THKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
LW PD Y N+K +++ T SS+TL + ++ YS H + +C+M+ + +PMD Q
Sbjct: 55 YLWFPDTYCSNAKRSDLMSPDTEIHSSLTLEPDGSIFYSRSAHIVASCEMDLRDFPMDTQ 114
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
+C + S+ Y++ ++ W + I ++ Q+ +G + +T Y+ GNY+
Sbjct: 115 TCNLVFGSYGYTDNDIKLSWKSTKILI-ANKEMAQFSLGDCVLSSKTMEYV---QGNYTL 170
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLD 224
L F R+IG++ IQ + P + +VMLSW FW++
Sbjct: 171 LSASFPMHRRIGYYAIQMYVPCTFLVMLSWIVFWMN 206
>UniRef50_A7RT31 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 443
Score = 118 bits (285), Expect = 2e-25
Identities = 66/251 (26%), Positives = 124/251 (49%), Gaps = 5/251 (1%)
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIA-ELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+TL N PDPY N++ + + E S +++ + + YS + + +C+M+
Sbjct: 93 ITLTVSAASNACKPDPYCYNARQSNMMLEDKDVNSRLSIDPDGKIFYSRGVSIVASCEMD 152
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELK-LLQYHIGQPLRLEETNGY 178
+P+D Q+C + S+++++ + FRW+ + L Q+H+ + ET Y
Sbjct: 153 LHDFPLDTQNCYLKFGSYAFTDTDIFFRWNNPNKLSRVQKSDLAQFHLAGYDLITETGIY 212
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
++GNY+ + V F+ R++G+++IQ + P L+V+LSW FW+D+ + R
Sbjct: 213 ---EEGNYTTVKVIFKMNRRVGYYIIQAYCPDVLIVVLSWIIFWMDVKDMGDRMALGITT 269
Query: 239 XXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQ 298
+ A +P V+Y KALD ++ FVF L E ++V +L Q + K K
Sbjct: 270 ILTIMFLLGAVNASMPKVSYPKALDWYLMVSFAFVFLTLIESMIVFLLTPQGESEKPKKT 329
Query: 299 ESMPRIIPVRL 309
+ + + L
Sbjct: 330 SCLTKRVVTML 340
>UniRef50_Q6BET0 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 536
Score = 118 bits (284), Expect = 3e-25
Identities = 81/304 (26%), Positives = 138/304 (45%), Gaps = 12/304 (3%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP G+P V +++ + ++ + + + RQ W++ RL G +
Sbjct: 78 RPGFNSGKPTKVYIDLFIRTMGPVSDLFNTYSFNCYFRQKWTDDRLHFNNSGI--GFRQL 135
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+L D +W PD YF N + + +T V L + T+ YS+R+ CQM+
Sbjct: 136 SLSMAMLDKIWKPDTYFWNGAGSYVHGITTSNRLVRLEPDGTILYSSRITVKAKCQMDMS 195
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRW----SEAGVTINPE--LKLLQYHIGQPLRLEET 175
YP+D Q+C + I S++YS+ +V+++W + GV I+ E L Q+ + +
Sbjct: 196 RYPLDKQACRLVIGSYAYSSDEVQYKWRIMGDDNGVKIDYESIADLPQFSLSGFKVYKPA 255
Query: 176 NGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXX 235
N I +D YS L V F F+R G+ L+ + P +LVV+L W +F+ +A R
Sbjct: 256 N---ITRDKEYSALEVRFYFDRHFGYFLMNFYVPCALVVLLCWVAFFTKREATAERIGIG 312
Query: 236 XXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKN 295
++D P V AL++++ C + + EF VV K Y
Sbjct: 313 ITNVLTIVLISMDSKSDSPKVDSPTALEVFIWICYLTHLICMVEFTVVHYHTK-YNTGDP 371
Query: 296 KAQE 299
+ QE
Sbjct: 372 EIQE 375
>UniRef50_UPI0000EB6CC4 Cluster: glycine receptor, beta b; n=1;
Danio rerio|Rep: glycine receptor, beta b - Danio rerio
Length = 451
Score = 116 bits (279), Expect = 1e-24
Identities = 56/165 (33%), Positives = 90/165 (54%), Gaps = 3/165 (1%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV +I++ SI MD+RV++F+RQ W++ RL+LP+D D +T+
Sbjct: 81 PNFKGIPVEDRVNIFINSFGSIQETTMDYRVNIFLRQRWNDPRLRLPQDF---KSDSLTV 137
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P+ F LW PD +F N K ++T + + ++RN V S R+ ++C ++ L+
Sbjct: 138 DPKMFKCLWKPDLFFANEKSANFHDVTQENILLFIFRNGDVLISMRLSVTLSCPLDLTLF 197
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQ 168
PMD Q C + +ESF Y+ ++F W E+ L Q+ I Q
Sbjct: 198 PMDTQRCKMQLESFGYTTDDLQFMWQSGDPVQMDEIALPQFDIKQ 242
Score = 51.2 bits (117), Expect = 5e-05
Identities = 19/40 (47%), Positives = 32/40 (80%)
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T L +++P V+YVKA+D+W+ C++F FA+L E+ VV+V+
Sbjct: 270 TSLASELPKVSYVKAIDIWLIACLLFGFASLVEYAVVQVM 309
>UniRef50_A7SVS1 Cluster: Predicted protein; n=5; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 318
Score = 115 bits (276), Expect = 3e-24
Identities = 83/301 (27%), Positives = 151/301 (50%), Gaps = 20/301 (6%)
Query: 11 VIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDN 70
V ++ + ++ ++ +M+F VDM++ Q W E RL I E + L +
Sbjct: 26 VDIQLDMLILSFGELSETNMEFTVDMYLGQFWKEPRLAF--GIKRE----IILSGVASEK 79
Query: 71 LWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQT---VRYSARMHAIIACQMEFQLYPMDI 127
LW PD +F+NS T++ L FS+ ++ N T V SAR+ +C+++ + YPMD
Sbjct: 80 LWVPDTFFVNSIDTKVHALL--FSNKKVWINLTDGSVMLSARLTTRNSCKVDLRNYPMDE 137
Query: 128 QSCPIYIESFSYSNQKVRFRW-SEAGVTIN-PELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + ESFSY + + + W S+ G I + ++ Q+ I R + + +
Sbjct: 138 QTCHLPFESFSYEQKDLNYTWRSKVGSDIAIYDKEMAQFDIIAAKRFLK---HPVYHSPM 194
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
+S L F R+ +++ Q + P + VV+LSW +FW+D R
Sbjct: 195 FSGLTATMSFRRRSLYYIFQMYIPCTCVVILSWIAFWIDPKEGSERVGLGISAVLTISYM 254
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRII 305
+ A +P V+Y+K++D ++ +FVF +L E+V+V + D + + K + ++P I+
Sbjct: 255 RGSMNAGMPRVSYLKSIDYFLLISFVFVFMSLIEYVLV-LKDARKERRK---KITLPGIL 310
Query: 306 P 306
P
Sbjct: 311 P 311
>UniRef50_P90876 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 618
Score = 114 bits (275), Expect = 4e-24
Identities = 75/305 (24%), Positives = 141/305 (46%), Gaps = 16/305 (5%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQ--LPEDIFEEGDDH 60
P V V+ I V +++ + MD+ +D ++R +W + RL+ L I +D+
Sbjct: 265 PSLHVDDTVTVKVGIAVQSMSNFELSTMDYDLDAWVRMSWIDPRLRHDLSRPILV--NDY 322
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAI-IACQME 119
F +W PDP F NSK + ++T+ + ++ + + R++ A Q+
Sbjct: 323 T-----FLKMIWRPDPIFTNSKYSTFHKVTYLNFYLFIFPDGKIFMDMRVYLKPTAAQIV 377
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRW---SEAGVTINPELKLLQYHIGQPLRLEETN 176
YP D + + I S ++ V+ W + + I +K+ + I + L + N
Sbjct: 378 LCKYPHDNPAVSLKISSMGFTQDVVKLEWFSDTNDAIWIEKNVKIPELSI-RHLHPDTCN 436
Query: 177 GYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXX 236
G + K G YS L F R++G+H+ T+ P+++ V+ SW S WL + + GR
Sbjct: 437 G--VRKSGVYSCLEAKFYMHREVGYHIANTYIPTAICVVFSWISVWLPEEFVEGRIFVSL 494
Query: 237 XXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
+ ++P V+YVKA+D+W FVF + + +VV L+ + + K
Sbjct: 495 TVFLTLSAENNSAKEELPKVSYVKAIDIWFGFTSTFVFLTMLQALVVISLEHNSKRLRLK 554
Query: 297 AQESM 301
+ ++
Sbjct: 555 FENNL 559
>UniRef50_UPI0000F1E22C Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 447
Score = 105 bits (252), Expect = 2e-21
Identities = 61/199 (30%), Positives = 103/199 (51%), Gaps = 10/199 (5%)
Query: 108 ARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPE-LKLLQ 163
+R+ C M+ + +PMD +CP+ S++Y +V ++W++ V + E +L Q
Sbjct: 159 SRLTISAECPMQLEDFPMDAHACPLKFGSYAYPISEVVYKWTKGPGKSVVVAEEGSRLNQ 218
Query: 164 YH-IGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFW 222
YH IG E+ + G Y+ ++ +F +R+IG+ +IQT+ P + V+LS SFW
Sbjct: 219 YHLIGHTAGTEDIS----TSRGQYTVMMAHFYLKRKIGYFVIQTYMPCFMTVILSQVSFW 274
Query: 223 LDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVV 282
L+ +++P R R +P VAY A+D ++A C FVF+AL EF
Sbjct: 275 LNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFAT 334
Query: 283 VKVLDKQ-YQMNKNKAQES 300
V K+ + + KA E+
Sbjct: 335 VNYFTKRSWAWDGKKALEA 353
Score = 34.3 bits (75), Expect = 6.0
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+IDK+SR+VFP LF F +YW L
Sbjct: 412 KIDKMSRIVFPVLFGTFNLVYWATYL 437
>UniRef50_Q24352 Cluster: Gamma-aminobutyric acid receptor
alpha-like precursor (GABA(A) receptor alpha-like and
glycine receptor-like subunit of Drosophila); n=3;
Diptera|Rep: Gamma-aminobutyric acid receptor alpha-like
precursor (GABA(A) receptor alpha-like and glycine
receptor-like subunit of Drosophila) - Drosophila
melanogaster (Fruit fly)
Length = 686
Score = 100 bits (240), Expect = 6e-20
Identities = 53/161 (32%), Positives = 80/161 (49%), Gaps = 7/161 (4%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G P +E I V + I+ DM + +D + RQ+W + RL FE D + L
Sbjct: 130 GPPATIEVDIMVRSMGPISEVDMTYSMDCYFRQSWVDKRLA-----FEGAQDTLALSVSM 184
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+W PD YF N K + + +T V +Y+N V YS+R+ C M +PMDI
Sbjct: 185 LARIWKPDTYFYNGKQSYLHTITTPNKFVRIYQNGRVLYSSRLTIKAGCPMNLADFPMDI 244
Query: 128 QSCPIYIESFSYSNQKVRFRWSE--AGVTINPELKLLQYHI 166
Q CP+ SF Y+ V +RW++ V I ++KL Q+ +
Sbjct: 245 QKCPLKFGSFGYTTSDVIYRWNKERPPVAIAEDMKLSQFDL 285
Score = 72.5 bits (170), Expect = 2e-11
Identities = 37/103 (35%), Positives = 53/103 (51%)
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
YS L+V F +R +G+ LIQ + P L+V+LSW SFWL+ +A R
Sbjct: 378 YSMLMVNFHLQRHMGNFLIQVYGPCCLLVVLSWVSFWLNREATADRVSLGITTVLTMTFL 437
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDK 288
R D+P V+Y ALD ++ F+FA + +F VV K
Sbjct: 438 GLEARTDLPKVSYPTALDFFVFLSFGFIFATILQFAVVHYYTK 480
>UniRef50_Q7YTP9 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 679
Score = 99.5 bits (237), Expect = 1e-19
Identities = 74/295 (25%), Positives = 135/295 (45%), Gaps = 13/295 (4%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVT 62
P A PV V + + + + + E M+F +D+ + +W + RL + + + +
Sbjct: 336 PLAFNDIPVNVAVAFNFLYLANFDSEMMEFSMDVEMEFSWIDIRLV---NNYTK-PIRIR 391
Query: 63 LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQL 122
P + +W PDPY +NSK + ++ + + V Y+ R+ ++ +C M F L
Sbjct: 392 EKP-IIEQIWRPDPYIVNSKHSYFHYVSFPNIRMRITPEGLVTYTVRVSSVCSCFMSFCL 450
Query: 123 YPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLE-ETNGYMID 181
YP D Q C + I S +YSNQ V+F W + ++ L + HI + E T G ++D
Sbjct: 451 YPHDRQECDLRISSIAYSNQYVKFHWHSNPIKFQSKITLPELHITKIKTAECSTKGKLVD 510
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
S L + F ER +I+ + PS+L +M +W + ++ + R
Sbjct: 511 A----SCLRIIFSLERDSARFVIEKYVPSTLAMMFAWVAPYVPYNYEDVRIITPITVLLT 566
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMF-VFAALGEFVVVKVLDKQYQMNKN 295
G + +I +Y+ ++D+W A F V + L V+ ++ + M KN
Sbjct: 567 LVQMEKGDK-EI-RTSYLTSIDVWFAAMKSFTVLSLLESLAVLALIKRSRAMTKN 619
>UniRef50_Q0GQQ7 Cluster: PH-sensitive chloride channel variant 4;
n=2; Apocrita|Rep: PH-sensitive chloride channel variant
4 - Apis mellifera (Honeybee)
Length = 489
Score = 99.5 bits (237), Expect = 1e-19
Identities = 75/312 (24%), Positives = 139/312 (44%), Gaps = 36/312 (11%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V S+ ++ + S + + + V+ ++Q W + RL+ E + + +D++W
Sbjct: 88 VNVSVLLLSLASPDESSLKYEVEFLLQQQWYDPRLRYSNRSQYEFLNAI----HHYDDIW 143
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD YF+ + + F+ + +YRN TV Y R H I++CQ ++P D C
Sbjct: 144 LPDTYFIMHGDFKDPLIPVHFA-LRIYRNGTVNYLMRRHLILSCQGRLNIFPFDDPLCSF 202
Query: 133 YIESFSYSNQKVRFRW--SEAGVTINPELKLLQYH------IGQPLRLE-ETNG-YMIDK 182
IES SY + + W E + +P L L + I P+++ +G M+D
Sbjct: 203 AIESISYEQTAITYVWKNDEGTLRKSPSLTSLNAYLIKNQTITCPIKVSWRADGQIMVDY 262
Query: 183 DGNYSRL------VVYFRFERQIGHHLIQ---------------TFAPSSLVVMLSWFSF 221
+ + + RFE Q + ++ F P ++V S+ +F
Sbjct: 263 EDEFDEFGDSKCSLCQRRFEEQGNYSCLKVDLIFTRDRAFYFTTVFIPGIILVTSSFITF 322
Query: 222 WLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFV 281
WL+ +A+P R G R+ +P V+ + A+++W CM F++A+L EFV
Sbjct: 323 WLEWNAVPARVMIGVTTMLNFFTTSNGFRSTLPVVSNLTAMNVWDGVCMCFIYASLLEFV 382
Query: 282 VVKVLDKQYQMN 293
V + ++ M+
Sbjct: 383 CVNYVGRKRPMH 394
>UniRef50_Q4RN70 Cluster: Chromosome undetermined SCAF15016, whole
genome shotgun sequence; n=22; Eukaryota|Rep: Chromosome
undetermined SCAF15016, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 269
Score = 96.7 bits (230), Expect = 1e-18
Identities = 51/168 (30%), Positives = 95/168 (56%), Gaps = 9/168 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP G PV V S+ + +++I+ +MD+ +F+RQ W++ RL +FE G+
Sbjct: 40 LRPFFDNG-PVTVGMSLDIASIDTISEINMDYTATIFLRQRWTDERL-----VFE-GNKS 92
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
++L + LW PD + ++SK + + ++T + + ++ N TV Y+ R+ +AC M+
Sbjct: 93 LSLDGRLVELLWVPDTFIVDSKKSFLHDITVENRLIRIFPNGTVLYALRITTTVACNMDL 152
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHI 166
YPMD Q+C + +ES+ Y+ V F W+ +++ L+L QY +
Sbjct: 153 TKYPMDKQTCTLQLESWGYNINDVMFYWTRGNESVSGLDTLQLAQYTV 200
>UniRef50_UPI0000ECC613 Cluster: Gamma-aminobutyric-acid receptor
subunit beta-1 precursor (GABA(A) receptor subunit
beta-1).; n=1; Gallus gallus|Rep:
Gamma-aminobutyric-acid receptor subunit beta-1
precursor (GABA(A) receptor subunit beta-1). - Gallus
gallus
Length = 382
Score = 87.4 bits (207), Expect = 6e-16
Identities = 59/203 (29%), Positives = 101/203 (49%), Gaps = 13/203 (6%)
Query: 31 DFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELT 90
D+ + M+ +Q+W E RL + ++TL D+LW D YF N K + + +
Sbjct: 1 DYTLTMYFQQSWREKRLP-----YSGISLNLTLDNRAADHLWVSDTYFQNDKNSFVQGVM 55
Query: 91 HKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWS- 149
K ++ + + TV Y R+ AC M+ YP+D Q+C + I S Y+ + F W+
Sbjct: 56 VK-QTIQYHPDGTVLYGLRI-TTAACMMDLHRYPLDEQNCTLEIYSNGYTTNDIEFYWNG 113
Query: 150 -EAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFA 208
++ VT ++L Q+ I + + + G Y +L + F +R G+ +QT
Sbjct: 114 GKSAVTGVSNIELPQFSIVDYKTVSKRVEF---PTGTYPQLSLSFWLKRNTGYFTLQTHM 170
Query: 209 PSSLVVMLSWFSFWLDLDAIPGR 231
PS+L+ +LS SFW++ DA R
Sbjct: 171 PSTLITILSRVSFWIN-DASAAR 192
>UniRef50_A0YQU9 Cluster: Putative uncharacterized protein; n=1;
Lyngbya sp. PCC 8106|Rep: Putative uncharacterized
protein - Lyngbya sp. PCC 8106
Length = 343
Score = 85.4 bits (202), Expect = 2e-15
Identities = 70/312 (22%), Positives = 129/312 (41%), Gaps = 15/312 (4%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP + +G V +YV+D+ I+ F VD FI W + L + + +
Sbjct: 37 RPFSEQGATE-VSVGLYVIDLFKIDEARQSFEVDFFIEFRWKDPHL-----VMSQSHCSI 90
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+ D +WHP N + LT F + + + TV R H +++ + +
Sbjct: 91 ASCRKNLDEIWHPAARIFNQR-----NLTKNFETTVVAPDGTVVCGQRFHGLVSSPLNLK 145
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMID 181
+P D Q+ I I SF +S +V+F + + E+ L + P+ + ++
Sbjct: 146 RFPFDEQTLRIQIMSFVFSPDEVQFVVNHHLTGLAEEISLPNWSTNIPV-AHNGSRHIAQ 204
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAI-PGRXXXXXXXXX 240
+ ++ + +R +++ + P L+V++S+ FW I P
Sbjct: 205 LNQSFVCFDYELKVKRYTAYYITRVILPLILIVLMSYAVFWFPPGQIMPQVTISVTAILS 264
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFV-VVKVLDKQYQMNKNKAQE 299
FT L+ +P V Y+ LD ++ G M+ VF AL E V +++ + + Q
Sbjct: 265 LITYEFT-LQQSLPQVPYLTVLDKFVIGAMVLVFLALVETVTTIELAEVKLQFLALDLDN 323
Query: 300 SMPRIIPVRLNG 311
+ I P L G
Sbjct: 324 WLRWIFPAFLTG 335
>UniRef50_Q61R47 Cluster: Putative uncharacterized protein CBG06736;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG06736 - Caenorhabditis
briggsae
Length = 394
Score = 84.2 bits (199), Expect = 6e-15
Identities = 50/177 (28%), Positives = 86/177 (48%), Gaps = 12/177 (6%)
Query: 132 IYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD---GNYSR 188
++ +FSY+N++VR +W+ P + + + T G I +D G +
Sbjct: 208 LFFLNFSYNNEEVRLQWNSQR---KPVFAIQPIRLADFTLKDITTG-TISRDYPAGKWDE 263
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
L+V F FER+ + +Q + P+ + +SW +F L AI R F
Sbjct: 264 LIVTFVFERRYMWYFLQAYLPTFFSIFISWIAFSLGPQAITPRTMIGVNALLSMIFHFGS 323
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRII 305
+ ++P V+Y+KA+D+WM G M+FVF +L E VV Y + + + +E + II
Sbjct: 324 IMKNLPKVSYIKAIDVWMLGSMLFVFLSLVELAVV-----GYTLQRRRGKEHIVEII 375
Score = 73.3 bits (172), Expect = 1e-11
Identities = 43/143 (30%), Positives = 77/143 (53%), Gaps = 5/143 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P + G V VEF ++ +++SI+ DF ++++I + W++ L+ ++TL
Sbjct: 44 PKKGGITVSVEF--WIQEISSISEMTNDFEMEIYINEMWTDPNLKFSH--LGACKANLTL 99
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+ + LW P+ F+NSK EI E + +TL+ N TV + R+ C+ME +
Sbjct: 100 YEQTLNKLWKPNTCFVNSKFAEIYESPFQNVFLTLFDNGTVWVNYRLRVKGPCEMELTNF 159
Query: 124 PMDIQSCPIYIESFSYSNQKVRF 146
PMD Q+C + +SF Y++ + F
Sbjct: 160 PMDTQACRLNYQSF-YNSTLIVF 181
>UniRef50_Q45U92 Cluster: GABA-A receptor; n=3; Caenorhabditis|Rep:
GABA-A receptor - Caenorhabditis remanei
Length = 206
Score = 83.4 bits (197), Expect = 1e-14
Identities = 48/142 (33%), Positives = 68/142 (47%), Gaps = 3/142 (2%)
Query: 156 NPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVM 215
NP++KL + +I R E T K G +S L FR +R +G H+ QT+ P+SL +M
Sbjct: 4 NPDVKLPELYID---RYETTTCANERKSGAFSCLRAVFRLKRDVGFHIAQTYIPTSLALM 60
Query: 216 LSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFA 275
SW WL + + GR G R +P V+Y+KA+DLW FVF
Sbjct: 61 FSWVGVWLPEEFMEGRIGVAITVLLTLSTESAGAREHLPSVSYLKAIDLWFGFITGFVFF 120
Query: 276 ALGEFVVVKVLDKQYQMNKNKA 297
L + + V DK+ K A
Sbjct: 121 TLLQTLFVIGFDKRANQLKKWA 142
>UniRef50_A7SCG3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 201
Score = 81.8 bits (193), Expect = 3e-14
Identities = 38/111 (34%), Positives = 58/111 (52%)
Query: 184 GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXX 243
GN+S L V FRF R++ ++L + + P+SL V++SW SFW+ A P R
Sbjct: 5 GNFSALTVGFRFRREVYYYLFRFYIPASLTVVMSWVSFWISPLATPARISLTIITVLAMA 64
Query: 244 XXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNK 294
G D P +Y ++ D++M C +FVF L E+ V L + + NK
Sbjct: 65 GFLIGDHPDFPKSSYARSFDVYMMMCFVFVFGCLVEYAAVHYLLRDDKYNK 115
Score = 35.9 bits (79), Expect = 2.0
Identities = 11/22 (50%), Positives = 20/22 (90%)
Query: 386 EIDKLSRVVFPALFLLFVTMYW 407
++D++SR++FP +F+LF T+YW
Sbjct: 178 KLDEISRILFPVMFILFNTVYW 199
>UniRef50_Q4BXY7 Cluster: Neurotransmitter-gated ion-channel
ligand-binding; n=2; Chroococcales|Rep:
Neurotransmitter-gated ion-channel ligand-binding -
Crocosphaera watsonii
Length = 340
Score = 79.4 bits (187), Expect = 2e-13
Identities = 67/281 (23%), Positives = 120/281 (42%), Gaps = 22/281 (7%)
Query: 4 PARKGQPVIVEF--SIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
P P I + IY +D+ IN + +D ++ W +SR F+ +
Sbjct: 30 PRPNDDPEITQILVGIYTLDLAKINEVEQTVYIDFYLGLQWYDSR-------FDSALSNT 82
Query: 62 TLPP--EFFDNLWHPDPYFLNSKVT--EIAELTHKFSSVTLYRNQTVRYSARMHAIIACQ 117
L P + +W P+ + +N + E+ E+ H + V Y R + +A
Sbjct: 83 NLSPYQRKLEEVWQPNLHIINQRNLDKELDEIVH------INSQGIVTYRQRYYGKLATS 136
Query: 118 MEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNG 177
++ + +P D Q+ I + SFSYS +++ F +E I+ E+ L+ + I L
Sbjct: 137 LDLRRFPFDEQTIKIELISFSYSPEEIHFVEAEELNGISSEISLVNWSI-IGLSSHSHAH 195
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLD-LDAIPGRXXXXX 236
Y+ + +Y+R + +R + + P +L+V +S FWL+ IP
Sbjct: 196 YLQPEQQDYARFDYEIKVKRHSSFYAWRVLFPVALIVFMSDLVFWLEPTQIIPQITLATA 255
Query: 237 XXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAAL 277
F LR ++P + Y+ A D + G M+ VF AL
Sbjct: 256 TMVSLITYQFI-LRQELPKMNYLTAEDKVIVGSMLLVFIAL 295
>UniRef50_A7SDE9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 299
Score = 79.0 bits (186), Expect = 2e-13
Identities = 45/145 (31%), Positives = 71/145 (48%), Gaps = 7/145 (4%)
Query: 138 SYSNQKVRFRWS---EAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFR 194
SY+ Q +++RW + V + L Q+ + + +E Y + GN +R+ V F
Sbjct: 159 SYTTQDIKYRWRPPMNSSVDVRSR-NLAQFALTSIIEVEYVEHYDL---GNQNRMCVCFT 214
Query: 195 FERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIP 254
F+R++G+ LIQ + PS VV+LSW FW+D D + R + A +P
Sbjct: 215 FQRRLGYFLIQVYIPSIFVVVLSWIVFWMDKDNMGDRMALGITTVLTIMFLLGAVNASMP 274
Query: 255 PVAYVKALDLWMAGCMMFVFAALGE 279
V+Y KALD ++ VF L E
Sbjct: 275 RVSYPKALDWYLMVSFTLVFLVLIE 299
Score = 69.7 bits (163), Expect = 1e-10
Identities = 42/134 (31%), Positives = 67/134 (50%), Gaps = 9/134 (6%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV+V+ SIYV +I +M+++ + RQ W + RL + V L +
Sbjct: 1 GPPVVVDLSIYVSSFGNIEEANMEYKFFGYFRQFWKDERLA------NRVNHSVILKGDE 54
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSS-VTLYRNQTVRYSARMHAIIA-CQMEFQLYPM 125
+W PDP+ N++ + + + +S VT++ N V YS RM I A C++ +PM
Sbjct: 55 ISRMWRPDPFCYNARKSSLTDADADINSMVTIHPNGDVVYS-RMTIITAECELNLHKFPM 113
Query: 126 DIQSCPIYIESFSY 139
D Q C + I S Y
Sbjct: 114 DEQKCHLKIGSCEY 127
>UniRef50_UPI0000D9B066 Cluster: PREDICTED: gamma-aminobutyric acid
A receptor, alpha 2 isoform 2; n=2; Euteleostomi|Rep:
PREDICTED: gamma-aminobutyric acid A receptor, alpha 2
isoform 2 - Macaca mulatta
Length = 403
Score = 77.0 bits (181), Expect = 9e-13
Identities = 36/104 (34%), Positives = 56/104 (53%)
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y+ + +F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 189 YTVMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTL 248
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
R +P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 249 SISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 292
Score = 66.1 bits (154), Expect = 2e-09
Identities = 35/131 (26%), Positives = 61/131 (46%), Gaps = 5/131 (3%)
Query: 16 SIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPD 75
+IYV ++ DM++ +D+F RQ W + RL+ F+ + + L +W PD
Sbjct: 71 NIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLK-----FKGPMNILRLNNLMASKIWTPD 125
Query: 76 PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIE 135
+F N K + +T + + + T+ Y+ R+ C M + +PMD SCP+
Sbjct: 126 TFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFG 185
Query: 136 SFSYSNQKVRF 146
S Y+ F
Sbjct: 186 SCEYTVMTAHF 196
>UniRef50_A6FXF8 Cluster: Putative uncharacterized protein; n=1;
Plesiocystis pacifica SIR-1|Rep: Putative
uncharacterized protein - Plesiocystis pacifica SIR-1
Length = 394
Score = 76.2 bits (179), Expect = 2e-12
Identities = 60/278 (21%), Positives = 116/278 (41%), Gaps = 11/278 (3%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPED-IFEEGDDHV 61
PP + + + I +V+V++ + F+ ++F+ W + RL E+ I E + +
Sbjct: 77 PPHTPTKVEVGMYLISLVEVSAPSESFPTFKAEIFLDLEWHDPRLAFSEESIGTEREVFL 136
Query: 62 TLPPEF-FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
E + +W PD F N E E + + ++ + V YS R + ME
Sbjct: 137 EHEAELELERIWWPDIEFEN----EQGERHTESRELVIHHDGHVEYSERFQGVFTVDMEL 192
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
+P D Q+ I+ ESFS+ ++ V F N + K L++ + + E +
Sbjct: 193 IKFPFDHQNLTIHAESFSWDDRYVVFEPLPEKTGFNEDFKTLEWTL-HDVHTEVHAKKEV 251
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
D +S V +R G++L + P ++V +W +FW+ + R
Sbjct: 252 RSDEAFSEYVYSVNVDRDPGYYLYKIVIPLLIIVAFNWATFWMPGEPASVRMERTVIALL 311
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALG 278
+ ++P + Y+ +D G + FA++G
Sbjct: 312 TVVAFHQVVATNLPRIGYLTFMD----GIVYVAFASVG 345
>UniRef50_A7NAE6 Cluster: Neurotransmitter-gated ion-channel ligand
binding domain protein; n=10; Francisella
tularensis|Rep: Neurotransmitter-gated ion-channel
ligand binding domain protein - Francisella tularensis
subsp. holarctica FTA
Length = 351
Score = 75.8 bits (178), Expect = 2e-12
Identities = 64/305 (20%), Positives = 132/305 (43%), Gaps = 21/305 (6%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF- 67
+P +++ S ++ D+ S++ + ++D+ R +W++ RL+ ++ EE + +F
Sbjct: 31 KPTLIKTSAFITDIQSLDEMNEQLQIDVIFRFSWNDQRLEFDKN--EEKTPYKLYQGDFQ 88
Query: 68 FDNL---WHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYP 124
+D + W P +N EI K + +Y N + Y+ + + M + +P
Sbjct: 89 YDEVFEGWKPQISIIN----EIGTPQIKARQIKIYPNGDIIYTEQRTLHLETPMRLEKFP 144
Query: 125 MDIQSCPIYIESFSYSNQKVRFRWS-EAGVTI------NPELKLLQYHIGQ-PLRLEETN 176
D Q+ YI F Y++++V+ +T+ +P + + ++H+ L+ E
Sbjct: 145 FDKQTLKTYIIPFGYNSKEVQLIVEPNHKITVKDYVKDHPNINVAEWHLSNFDLKNIEPI 204
Query: 177 GYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXX 236
Y K S L ER+ + L++ P +L+V+ W FW+D A+ R
Sbjct: 205 KYYYGKPQRISMLEFSISLERKPTNILLKVLIPLTLLVLAMWAIFWMDTKALSDRLNITF 264
Query: 237 XXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
+ +I + Y+ D ++ +F+ + E + V L K +NK+K
Sbjct: 265 IGILSVIAYQFLIEGEILDIDYLTFTDGFLLLSFSILFSTVLESLAVYWLIK---LNKDK 321
Query: 297 AQESM 301
M
Sbjct: 322 LARKM 326
>UniRef50_Q4SJX0 Cluster: Chromosome 1 SCAF14573, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14573, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 371
Score = 75.4 bits (177), Expect = 3e-12
Identities = 38/108 (35%), Positives = 59/108 (54%), Gaps = 5/108 (4%)
Query: 31 DFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELT 90
D+ + M+ +Q W + RL E + ++TL D LW PD YFLN K + + +T
Sbjct: 89 DYTLTMYFQQAWRDKRLSYSEIAY-----NLTLDNRVADQLWVPDTYFLNDKKSFVHGVT 143
Query: 91 HKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFS 138
K + L+ + TV Y R+ AC M+ + YP+D Q+C + IES+S
Sbjct: 144 VKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESWS 191
Score = 59.3 bits (137), Expect = 2e-07
Identities = 31/95 (32%), Positives = 54/95 (56%), Gaps = 5/95 (5%)
Query: 139 YSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFE 196
Y+ + F W + V+ +++L Q+ I +L N ++ G+Y RL + F+ +
Sbjct: 228 YTTDDIEFYWRGGDGAVSGVDKIELPQFSIVD-YKLISKN--VVFSTGSYPRLSLSFKLK 284
Query: 197 RQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGR 231
R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 285 RNIGYFILQTYMPSILITILSWVSFWINYDASAAR 319
>UniRef50_UPI00015ADFAB Cluster: hypothetical protein
NEMVEDRAFT_v1g9118; n=1; Nematostella vectensis|Rep:
hypothetical protein NEMVEDRAFT_v1g9118 - Nematostella
vectensis
Length = 135
Score = 73.7 bits (173), Expect = 8e-12
Identities = 39/122 (31%), Positives = 62/122 (50%), Gaps = 6/122 (4%)
Query: 31 DFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELT 90
DF +D+F+RQ WS+ RL+ E H TL +W PD + LN K +
Sbjct: 2 DFTLDLFLRQVWSDPRLRHGEP------RHHTLTGTDKHLIWLPDTFILNVKEAYHHHVP 55
Query: 91 HKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSE 150
S V + + V YS M A C+M+ YP+D Q+C + I S+++ + ++ ++W E
Sbjct: 56 SDNSQVAIEADGDVMYSIGMRATAGCEMDLSSYPLDTQTCQLRIMSYAHVSAELVYKWGE 115
Query: 151 AG 152
G
Sbjct: 116 EG 117
>UniRef50_A7SAR5 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 93
Score = 72.9 bits (171), Expect = 1e-11
Identities = 31/90 (34%), Positives = 48/90 (53%)
Query: 184 GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXX 243
G + + F F R IG+ L+Q +AP++L+V LSW +FW+ DA+P R
Sbjct: 4 GAWIHITASFVFNRNIGYSLLQVYAPTTLIVALSWLAFWIPRDAVPARITLSVTTILTIV 63
Query: 244 XXFTGLRADIPPVAYVKALDLWMAGCMMFV 273
R P V+YVKA+D+++ +FV
Sbjct: 64 TLMGSFRTQFPKVSYVKAVDVFLIVSFLFV 93
>UniRef50_Q70GM3 Cluster: Ligand-gated chloride channel subunit
precursor; n=3; Chromadorea|Rep: Ligand-gated chloride
channel subunit precursor - Dirofilaria immitis (Canine
heartworm)
Length = 406
Score = 71.7 bits (168), Expect = 3e-11
Identities = 68/289 (23%), Positives = 116/289 (40%), Gaps = 19/289 (6%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RPP R I + +N I D VD+++RQ W + RL D +G + V
Sbjct: 57 RPPVRDSADHSAIVVIASIFINRILWHDHQAVVDLYLRQQWEDGRLVYELDD-RDGIEEV 115
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+P ++W PD YF N +L T Y VR S+ M +
Sbjct: 116 VVPHN--RHIWIPDTYFSNGHDVNHEKLHRTVVEPTGY----VR-SSEMRTVTVPVEYGS 168
Query: 122 LYPMD-IQSCPIYIESFSYSNQKVRFRWSEAGVTINP-----ELKLLQYHIGQPLRLEET 175
YP + + + + S+ Y + + + W+ + T+ P EL Y + + +
Sbjct: 169 KYPFENTRMIKLRLSSYKYPIEDIVYLWANSPPTVIPVEVSQELLTGFYEFKEAVAEDCA 228
Query: 176 NGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD-AIPGRXXX 234
Y I G YS + V F + F PS L++++SW FW+ ++P
Sbjct: 229 GNYTI---GIYSCIDVLITFTGASSEAFWRIFIPSILLILVSWLHFWVHGSWSVPRTISA 285
Query: 235 XXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ ++ V +L +W+ C++F FA+L E+ +V
Sbjct: 286 AVPFLIFVSILIFYPQPNLTTYG-VSSLQIWLFFCLIFTFASLVEYFIV 333
>UniRef50_A7SQS7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 155
Score = 69.3 bits (162), Expect = 2e-10
Identities = 37/132 (28%), Positives = 63/132 (47%), Gaps = 3/132 (2%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V + ++ + IN +M+F M+ RQ W + RL + + + + PE
Sbjct: 23 GAPVNVSVTTFIEFIGDINEINMEFTTIMYFRQYWEDPRLAYADTGYTK---RLAFNPEM 79
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+W PD +F K ++T V ++ N T+ YS R+ C M+ + +PMD
Sbjct: 80 LKFIWVPDTHFPGIKDGLKNDITASNEVVRIFPNGTLLYSMRLKVTSQCPMDLRNFPMDS 139
Query: 128 QSCPIYIESFSY 139
Q C + +E+ Y
Sbjct: 140 QKCRLKMEACKY 151
>UniRef50_Q7NDN8 Cluster: Glr4197 protein; n=1; Gloeobacter
violaceus|Rep: Glr4197 protein - Gloeobacter violaceus
Length = 359
Score = 68.5 bits (160), Expect = 3e-10
Identities = 51/220 (23%), Positives = 98/220 (44%), Gaps = 10/220 (4%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVT 62
PP +P+ V IY+++ S++ + F+V+ F+ +W + RL D G T
Sbjct: 50 PPPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAF--DPVRSGVRVKT 107
Query: 63 LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQL 122
PE +W P+ F+N + A++ +++ + TV+Y R A + ++F+
Sbjct: 108 YEPE---AIWIPEIRFVNVENARDADVV----DISVSPDGTVQYLERFSARVLSPLDFRR 160
Query: 123 YPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDK 182
YP D Q+ IY+ S + + V N ++ L + I + + + ++
Sbjct: 161 YPFDSQTLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALE- 219
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFW 222
D S+L R RQ ++ P ++ +SW +FW
Sbjct: 220 DRLESKLDYQLRISRQYFSYIPNIILPMLFILFISWTAFW 259
>UniRef50_A4CWI3 Cluster: Putative uncharacterized protein; n=1;
Synechococcus sp. WH 7805|Rep: Putative uncharacterized
protein - Synechococcus sp. (strain WH7805)
Length = 386
Score = 66.9 bits (156), Expect = 9e-10
Identities = 65/313 (20%), Positives = 136/313 (43%), Gaps = 17/313 (5%)
Query: 3 PPARKG-QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
P RK +P+ V +I+V ++ I+ F+VD + TW +SR+ + E +G+ +
Sbjct: 68 PQERKEPKPIPVGVNIHVNEIPQISDTYNRFQVDGLLTSTWCDSRI-ISE--IPQGEAEL 124
Query: 62 TLPPEFFDNL----WHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQ 117
L +N W P F N ++E ++ ++ L N +V +AR + +
Sbjct: 125 ILFNNAAENWLSEHWSPQLEFTN----RVSEAFYQTQTIALRSNGSVERTARFEEQLGSE 180
Query: 118 MEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNG 177
+ + +P D Q ++++SFS+ V+ V+++ +L ++ I + LR N
Sbjct: 181 FKLEKFPFDQQLLKLFVQSFSWEQSIVKLVSLGDVVSLSRNARLPEWKI-KDLRYVIKNH 239
Query: 178 YMIDKDG-NYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXX 236
+K +SRL R+ G+++ + F P ++ S F + +DA R
Sbjct: 240 DDPEKGSKEFSRLSSTITISRRSGYYIYKIFLPLGILTFTSIFFLAIPIDAFADRMAFIS 299
Query: 237 XXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
+ + +P V Y+ D + +F F + E + + + + N ++
Sbjct: 300 GLLFTTLAYQIIIASSVPRVPYLTLGDTYT--IFLFTF-MISEVFIAYHISQNLRKNGSE 356
Query: 297 AQESMPRIIPVRL 309
++ R++ + L
Sbjct: 357 RVPAIERVMEIFL 369
>UniRef50_Q4RNA9 Cluster: Chromosome 1 SCAF15015, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF15015, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 201
Score = 63.7 bits (148), Expect = 9e-09
Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 1/88 (1%)
Query: 205 QTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPV-AYVKALD 263
+T+ PS+L+V+LSW SFW+ ++P R G R +P ++KA+D
Sbjct: 2 ETYVPSTLLVVLSWVSFWISQSSVPARTCIGVTTVLTMTTLMMGARTSLPNANCFIKAID 61
Query: 264 LWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+++ C F+F AL E+ Q+Q
Sbjct: 62 VYLGICFTFIFGALLEYACAHFYTMQHQ 89
>UniRef50_A7SQS5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 194
Score = 63.3 bits (147), Expect = 1e-08
Identities = 33/100 (33%), Positives = 51/100 (51%), Gaps = 1/100 (1%)
Query: 207 FAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWM 266
+ PS L+V+LSW SFW+D + R R +P V+YVK+L+L++
Sbjct: 2 YLPSYLIVILSWVSFWVDREQTAARIAMGITTVLTMATLIGSARVSLPKVSYVKSLELFL 61
Query: 267 AGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRIIP 306
C +FVF+A+ E+ V L + Q KN+ + I P
Sbjct: 62 IMCFLFVFSAILEYSFVSYLVFR-QRVKNREDYAQQLIEP 100
>UniRef50_Q4SXG5 Cluster: Chromosome undetermined SCAF12416, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF12416, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 643
Score = 62.9 bits (146), Expect = 2e-08
Identities = 51/233 (21%), Positives = 109/233 (46%), Gaps = 16/233 (6%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP Q V+V + + +N+++ + + + W++ RL P+D +G +
Sbjct: 39 VRPAVSPEQRVVVRVGMILSSFVGLNMKNEEMSTIVVMNLEWTDYRLSWSPKDY--DGIE 96
Query: 60 HVTLPPEFFDNLWHPDPYFLNSK--VTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQ 117
+ +P +W PD +N+ V E+A H V +Y N V ++ +C
Sbjct: 97 VLRIPS---GKIWLPDIVLINNNDGVFEVALQVH----VQVYSNGRVTWTPPALYCSSCG 149
Query: 118 MEFQLYPMDIQSCPIYIESFSYSNQKVRFRWS--EAGVTINPELKLLQ-YHIGQPLRLEE 174
++ + +P D Q+C + S++Y + ++ +++ G I E++L + Y G ++
Sbjct: 150 VKVEYFPFDWQNCSMQFRSYTYDSTEIDIQYALDSKGREIK-EIQLDEAYTEGGEWYIKH 208
Query: 175 TNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
+ D Y +V Y ER+ ++++ P L+ +++ F+F+L DA
Sbjct: 209 RPSRKVMLDDEYEGMVFYLIIERKPLYYVLNIILPCILITIIAIFNFYLPPDA 261
>UniRef50_UPI0000EBED4A Cluster: PREDICTED: similar to
gamma-aminobutyric acid receptor rho1 subunit; n=1; Bos
taurus|Rep: PREDICTED: similar to gamma-aminobutyric
acid receptor rho1 subunit - Bos taurus
Length = 299
Score = 62.5 bits (145), Expect = 2e-08
Identities = 27/85 (31%), Positives = 44/85 (51%)
Query: 218 WFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAAL 277
W SFW+D A+P R TG+ A +P V+Y+KA+D+++ +FVF ++
Sbjct: 120 WVSFWIDRRAVPARVPLGITTVLTMSTIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSV 179
Query: 278 GEFVVVKVLDKQYQMNKNKAQESMP 302
E+ V L + + K QE +P
Sbjct: 180 LEYAAVNYLTTVQERKERKPQEKLP 204
Score = 35.5 bits (78), Expect = 2.6
Identities = 13/29 (44%), Positives = 20/29 (68%)
Query: 381 RVLWREIDKLSRVVFPALFLLFVTMYWPV 409
R+ IDK SR++FPA ++LF +YW +
Sbjct: 269 RIDTHAIDKYSRIIFPAAYILFNLIYWSI 297
>UniRef50_Q18556 Cluster: Putative uncharacterized protein acr-9;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acr-9 - Caenorhabditis elegans
Length = 534
Score = 61.3 bits (142), Expect = 5e-08
Identities = 69/308 (22%), Positives = 129/308 (41%), Gaps = 17/308 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A +P++V IY+ + ++ ++ + +I W++ +L+ D E G
Sbjct: 44 RPVANASEPLVVSVKIYLQQILDVDEKNQVITLVAWIEYQWTDYKLKW--DPSEYGGIKD 101
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P + +W PD NS E + T+ + V Y ++ + ++C+++
Sbjct: 102 IRIPGNANAIWKPDVLLYNS-ADENFDSTYPVNYVVSYTGDVLQVPPGI-LKLSCKIDIT 159
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWS-EAGVTINPELKLLQYHI--GQ--PLRLEETN 176
+P D Q C + S++YS + R + G I+ E +QY++ G+ L + +
Sbjct: 160 YFPFDDQICHLKFGSWTYSGNFIDLRINGPEGKNISDEGIDVQYYVQNGEWNLLAVPARH 219
Query: 177 GYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXX 236
I + Y L Y +R+ ++ + PS L+ +++ F L DA G
Sbjct: 220 ETNIFDEQPYPSLFFYLIIQRRTLYYGLNLIIPSFLISLMTVLGFTLPPDA--GEKITLE 277
Query: 237 XXXXXXXXXFTGLRADI-PPVA-YVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNK 294
F + AD+ PP + V + + + CM+ V A+ VV VL K
Sbjct: 278 ITILLSVCFFLSMVADMTPPTSEAVPLIGAFFSCCMLVVSAS----VVFTVLVLNLHNRK 333
Query: 295 NKAQESMP 302
+ E P
Sbjct: 334 PETHEMSP 341
>UniRef50_A7SW63 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 324
Score = 60.9 bits (141), Expect = 6e-08
Identities = 46/224 (20%), Positives = 94/224 (41%), Gaps = 7/224 (3%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP PV ++ I + V +N D ++++IRQ W + L+ D F G +
Sbjct: 17 RPVLNVNDPVQLKLGIMLRQVIDLNERDQILTINVWIRQYWKDHLLKWNPDDF-GGIKSI 75
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKF-SSVTLYRNQTVRYSARMHAIIACQMEF 120
+ P D +W PD N L +K ++V + + + + A C+++
Sbjct: 76 NIAP---DRVWKPDVLLYNRTDLRFGSLNNKIDTNVIVNHDGSTTWLAPAIIKSECKIDV 132
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+ +P D+QSC + S+++ K+ E+G+ ++ + + Y+
Sbjct: 133 RFFPFDVQSCELTFGSWTHDGLKIDIHLKQESGIDTENFSDNREWFLKGTSGRRDVKMYI 192
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ Y + R+ ++ P+ ++ +LS FSF+L
Sbjct: 193 CCPE-PYPTVTYTIILRRRAMFYVFNMVLPTGVIALLSLFSFYL 235
>UniRef50_A7SI11 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 404
Score = 59.7 bits (138), Expect = 1e-07
Identities = 48/223 (21%), Positives = 97/223 (43%), Gaps = 5/223 (2%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP +P ++ F+I + + +N + ++I Q W + +LQ + + G V
Sbjct: 18 RPALDNNEPTVINFTIRLQQIYELNGQLQKMVSSVWIEQAWWDHKLQWDQSKYG-GIKEV 76
Query: 62 TLPPEFFDNLWHPDPYFLNS-KVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
LP +W PD LN+ + + + + ++ + V + N VR+ A + C+M+
Sbjct: 77 VLPERGV--IWVPDVVLLNNAEKSSMGKPVNEGNPVLVESNGVVRWLAPVVLKSRCKMDV 134
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
+ YP D Q C + S++ S ++R + V N + ++ + Q L +
Sbjct: 135 RSYPFDEQYCGLKFASWTGSQSELRLDAMDNDVRQNYS-ESSEWDLLQTYTLRSSAKATH 193
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
S + R +R + ++++ AP L +L+ F L
Sbjct: 194 SSPEKKSAIRYVIRIKRHVFYYIVYLLAPCLLTSLLAILLFTL 236
>UniRef50_A7S2J7 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 462
Score = 57.2 bits (132), Expect = 7e-07
Identities = 47/225 (20%), Positives = 96/225 (42%), Gaps = 8/225 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP V VEFS+ ++ + ++N + V ++IRQ W+ L + G +
Sbjct: 53 VRPVFNDSDKVNVEFSLSLIQIIAVNSKSQLVTVSVWIRQKWTNPMLAWNTSKY-GGIES 111
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKF-SSVTLYRNQTVRYSARMHAIIACQME 119
V L P +W PD N+ A K+ +SV + T +++ C +
Sbjct: 112 VNLNPA---KVWIPDIILYNNADETYAGGLEKYKTSVIASSDGTQEWNSPASFTSTCNIN 168
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYH-IGQPLRLEETNGY 178
+ +P D Q+C + S++Y ++ + ++ + ++H + P +L Y
Sbjct: 169 VRYFPFDSQNCSLKFGSWTYVGNRLTMTSTSDSADLSKYVNNGEWHLLAMPAKLNRV-FY 227
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
K Y + +Y +R+ +++ P +L+ L+ F+L
Sbjct: 228 NCCKYPFYD-VTLYLEIQRKPLYYVFNLIIPCALIATLTLIKFFL 271
>UniRef50_Q4T6F3 Cluster: Chromosome 7 SCAF8790, whole genome
shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 7
SCAF8790, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 66
Score = 56.4 bits (130), Expect = 1e-06
Identities = 22/48 (45%), Positives = 34/48 (70%)
Query: 184 GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGR 231
G+Y RL + F+ +R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 3 GSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAAR 50
>UniRef50_UPI0000E48B7E Cluster: PREDICTED: similar to neuronal
nicotinic acetylcholine receptor alpha3 subunit; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
neuronal nicotinic acetylcholine receptor alpha3 subunit
- Strongylocentrotus purpuratus
Length = 525
Score = 55.6 bits (128), Expect = 2e-06
Identities = 47/228 (20%), Positives = 96/228 (42%), Gaps = 9/228 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP + PV+V+F + + + +I+ ++ ++++ W + L PED EG
Sbjct: 48 IRPVKNESDPVVVKFGLSISQLIAIDEKNQVMTTSVWVKHEWQDHHLMWNPEDY--EGIT 105
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P E N+W PD N+ ++ +++ Y TV + +C ++
Sbjct: 106 ELHIPAE---NIWRPDILLYNNANGNF-DVQFLVNAIVKYTG-TVTWLPPAIYKSSCTID 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+ +P D QSC + +++ K+ S V ++ I + Y
Sbjct: 161 IEYFPFDEQSCKMKFGPWTHDTLKIDMASSNDVVDQEDYWPNGEWEIVESPATRNEITYP 220
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
D Y + +YF+ R+ +++ P L+ L+ F+L DA
Sbjct: 221 C-CDDKYVDVTLYFKLHRKPLFYVVTLVVPCLLISFLTILVFFLPSDA 267
>UniRef50_P11230 Cluster: Acetylcholine receptor subunit beta
precursor; n=30; Gnathostomata|Rep: Acetylcholine
receptor subunit beta precursor - Homo sapiens (Human)
Length = 501
Score = 54.4 bits (125), Expect = 5e-06
Identities = 52/238 (21%), Positives = 102/238 (42%), Gaps = 17/238 (7%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP G V V + + + S+N +D + +++ W++ RL + +G D
Sbjct: 42 VRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSW-DPAEHDGIDS 100
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ + E ++W PD LN+ SV + + +VR+ +C ++
Sbjct: 101 LRITAE---SVWLPDVVLLNNNDGNFDVALD--ISVVVSSDGSVRWQPPGIYRSSCSIQV 155
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFR---------WSEAGVTINPELKLLQYH-IGQPL 170
+P D Q+C + S+SY + +V + E + ++ Q+ I +P
Sbjct: 156 TYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQWEIIHKPS 215
Query: 171 RLEETNG-YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
RL + G ++G ++ Y R+ +L+ AP L+ +L+ F F+L DA
Sbjct: 216 RLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDA 273
>UniRef50_A6FMG2 Cluster: Putative uncharacterized protein; n=1;
Roseobacter sp. AzwK-3b|Rep: Putative uncharacterized
protein - Roseobacter sp. AzwK-3b
Length = 244
Score = 54.0 bits (124), Expect = 7e-06
Identities = 35/179 (19%), Positives = 69/179 (38%), Gaps = 1/179 (0%)
Query: 104 VRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQ 163
V Y R I+ + +P D I ++F +A ++ +L +
Sbjct: 26 VSYRQRFFGDISTYHNLRNFPFDTHDFAITFMPVGTGAATLKFVPDQANTWLSDQLNISG 85
Query: 164 YHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+H+ L L+E + + S L + +R++ ++L + P VV +SW FW+
Sbjct: 86 WHVNT-LSLQEQQAKLRESGHFLSMLTLTISADREVNYYLFRIMLPLFFVVAMSWVIFWV 144
Query: 224 DLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVV 282
+ + + +PP+ Y+ LD + + VF A+ E +V
Sbjct: 145 PPNRFEFQIGLGATSMLTVIAFNLAVAGSLPPLGYLTVLDQILIWSIAIVFLAIAEALV 203
>UniRef50_Q9NA46 Cluster: Putative uncharacterized protein acr-24;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acr-24 - Caenorhabditis elegans
Length = 540
Score = 54.0 bits (124), Expect = 7e-06
Identities = 38/163 (23%), Positives = 78/163 (47%), Gaps = 12/163 (7%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP +P V FS+ + + SIN + + ++++ Q W++ L ++ G +
Sbjct: 15 VRPVMNHSKPTTVSFSMSLYQILSINEKQQNVDLNVWAIQKWNDDFLGWNPYLY--GMIN 72
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTL----YRNQTVRYSARMHAII-- 114
T+ P FD +W PD Y NS V E T ++ +V + ++ +T M+ +
Sbjct: 73 TTILP--FDAIWLPDTYLYNSVVMN-REETERYINVVVTTNYWKGETGAEVKFMYPALYR 129
Query: 115 -ACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTIN 156
+C ++ + +P D Q+C + I S++ S + + V ++
Sbjct: 130 TSCLLDIRFFPYDQQACKLTISSWTSSKSDINYEPEHESVNMD 172
>UniRef50_Q6QWI5 Cluster: Acetylcholine receptor 20 (63.9 kD)
alternative variant a; n=5; Caenorhabditis|Rep:
Acetylcholine receptor 20 (63.9 kD) alternative variant
a - Caenorhabditis elegans
Length = 553
Score = 53.6 bits (123), Expect = 9e-06
Identities = 49/227 (21%), Positives = 99/227 (43%), Gaps = 13/227 (5%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVT 62
P K P+ V FS+ + + S+N ++ ++ + W++ L + F + +
Sbjct: 41 PSMGKKSPIEVHFSMELYQIISVNEPQQFLMLNAWVVERWTDRLLGWDPEKFGNVTE-IM 99
Query: 63 LPPEFFDNLWHPDPYFLNSKVTEIAELTHKF-SSVTLYRNQTVRYSARMHAII---ACQM 118
LP F +W PD NS V + E + VT + ++ I +C +
Sbjct: 100 LPHHF---IWLPDTTLYNSLVMKDDENRRLLHAKVTTLGEGNGAFIELLYPTIYKLSCLL 156
Query: 119 EFQLYPMDIQSCPIYIESFSYSNQKV---RFRWSEAGVTINPELKLLQYHIGQPLRLEET 175
+ +P D+QSC + S+++ N K+ F S+A T N ++ +++ +
Sbjct: 157 NLRFFPFDVQSCRLLFGSWTFDNTKIDYFAFNESQAIGTTNC-IENEGWNVLSTSVIRHE 215
Query: 176 NGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFW 222
N Y + NY+ L +R+ +++I P+S++ +S F+
Sbjct: 216 NKYDCCPN-NYTLLEFRLTIQRKPLYYIINLIIPTSIITFISIIGFF 261
>UniRef50_Q2XWK7 Cluster: Nicotinic acetylcholine receptor subunit
type F; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type F - Lymnaea
stagnalis (Great pond snail)
Length = 488
Score = 53.6 bits (123), Expect = 9e-06
Identities = 46/227 (20%), Positives = 94/227 (41%), Gaps = 15/227 (6%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP V VEF + ++ + ++V+D + +++ TWS+ L+ + ++ D V
Sbjct: 60 RPVVNTSDAVRVEFGLSLIQILDVDVKDQVLKTNVWYEYTWSDVLLKWDIEQYDNITD-V 118
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+P E ++W PD N + E + + V + + ++ + + +C
Sbjct: 119 RIPSE---HIWLPDILLYNFADDRLKE--QRNALVVVSHDGSLLWMPQAILRSSCAFNTL 173
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMID 181
+P D Q+C + S+SY+ K+ + + + L+ Y + E GY
Sbjct: 174 YFPFDEQTCVLKFGSWSYNGFKLDIHFKQG----RDKFDLMDYIENNEWTIIENEGYRNI 229
Query: 182 K-----DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
K Y L F R++ + P +L+ +L+ FW+
Sbjct: 230 KMYTCCPEPYPDLKFKLVFRRRVAFYTFILIMPCALLSLLTMVIFWV 276
>UniRef50_P48180 Cluster: Acetylcholine receptor subunit alpha-type
acr-16 precursor; n=3; Caenorhabditis|Rep: Acetylcholine
receptor subunit alpha-type acr-16 precursor -
Caenorhabditis elegans
Length = 498
Score = 53.6 bits (123), Expect = 9e-06
Identities = 62/293 (21%), Positives = 119/293 (40%), Gaps = 15/293 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A +PV V + + + ++ ++ V+ ++ TW++ L + + D V
Sbjct: 39 RPVANHSEPVTVHLKVALQQIIDVDEKNQVVYVNAWLDYTWNDYNLVWDKAEYGNITD-V 97
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P +W PD NS T + T++ +++ +Y V + I+C+++ Q
Sbjct: 98 RFPA---GKIWKPDVLLYNSVDTNF-DSTYQ-TNMIVYSTGLVHWVPPGIFKISCKIDIQ 152
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMID 181
+P D Q C S++Y K+ + + G I+ + ++ + PL E N D
Sbjct: 153 WFPFDEQKCFFKFGSWTYDGYKLDLQPATGGFDISEYISNGEWAL--PLTTVERNEKFYD 210
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
Y + Y R+ ++ P L +++ F L DA G
Sbjct: 211 CCPEPYPDVHFYLHMRRRTLYYGFNLIMPCILTTLMTLLGFTLPPDA--GEKITLQITVL 268
Query: 241 XXXXXFTGLRADI-PPVA-YVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
F + +++ PP + V L ++ CM+ V A+ V VL+ Y+
Sbjct: 269 LSICFFLSIVSEMSPPTSEAVPLLGIFFTCCMIVVTAS--TVFTVYVLNLHYR 319
>UniRef50_P48182 Cluster: Acetylcholine receptor subunit beta-type
acr-2 precursor; n=3; Rhabditida|Rep: Acetylcholine
receptor subunit beta-type acr-2 precursor -
Caenorhabditis elegans
Length = 575
Score = 53.2 bits (122), Expect = 1e-05
Identities = 55/279 (19%), Positives = 126/279 (45%), Gaps = 15/279 (5%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
PV+V+F + ++ + +++ ++ + ++++ W++ QL + E G+ P D
Sbjct: 85 PVVVDFGVAMILLINVDEKNQILQTNVWLTMKWND--FQLAWNPAEYGNISNLHVPS--D 140
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
+W PD N+ E++ K S+V + + V + +C+++ + +P D Q
Sbjct: 141 RVWLPDIVLFNNADGNY-EVSFK-SNVFVDHHGDVTWVPPAMFKSSCRIDVEWFPFDEQC 198
Query: 130 CPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDK-DGNYSR 188
C + S++Y++++VR W I ++L Y + + G ++ K D ++
Sbjct: 199 CTLVFGSWTYNSEEVRLHWYN---NIQ-AVQLHDYSYSGIWDVIDVPGQLVHKPDLKENK 254
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+V R+ + + P+ L+ LS +F+L +D+ G F
Sbjct: 255 MVFNVVIRRKTLFYTVILIIPTVLMAFLSVMAFYLPVDS--GEKVSLTISLLLALVVFLL 312
Query: 249 LRADI-PPVAYVKALDLW-MAGCMMFVFAALGEFVVVKV 285
L + I PP + + + + + ++ + A +G V+V +
Sbjct: 313 LVSKILPPTSNIPLMGKYLLLAFVLNITAVVGTVVIVNI 351
>UniRef50_O16926 Cluster: Acetylcholine receptor protein 15; n=2;
Caenorhabditis|Rep: Acetylcholine receptor protein 15 -
Caenorhabditis elegans
Length = 479
Score = 52.8 bits (121), Expect = 2e-05
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 6/144 (4%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP +PV+V +++ + +++ ++ V+ +++ W + L+ +E D +
Sbjct: 38 RPTLDSSKPVVVSLGVFLQQIINLSEKEEQLEVNAWLKFQWRDENLRWEPTAYENVTD-L 96
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
PP D LW PD NS +E + ++K + V Y + + ++C+++
Sbjct: 97 RHPP---DALWTPDILLYNSVDSEF-DSSYKVNLVN-YHTGNINWMPPGIFKVSCKLDIY 151
Query: 122 LYPMDIQSCPIYIESFSYSNQKVR 145
+P D Q C S++Y+ K++
Sbjct: 152 WFPFDEQVCYFKFGSWTYTRDKIQ 175
>UniRef50_P91197 Cluster: Acetylcholine receptor protein 11; n=2;
Caenorhabditis|Rep: Acetylcholine receptor protein 11 -
Caenorhabditis elegans
Length = 461
Score = 52.4 bits (120), Expect = 2e-05
Identities = 57/289 (19%), Positives = 115/289 (39%), Gaps = 14/289 (4%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP QP+ V+ +++ + ++ ++ V+ ++ TW + +LQ + G +
Sbjct: 42 RPVQNSSQPLEVKIKLFLQQILDVDEKNQIVSVNAWLSYTWFDHKLQWEPKKY-GGIQDI 100
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P D++W PD NS E + T K S++ Y TV + CQ++
Sbjct: 101 RFPGS-SDHIWKPDVLLYNS-AAEDFDSTFK-SNLLTYHTGTVVWIPPGVLKFVCQLDVT 157
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETN----- 176
+P D Q C + S+++ + + + + L Y + ++ TN
Sbjct: 158 WFPFDDQVCEMKFGSWTFHGYAIDLQIDD-DTNGTQSMDLSTYLVNGEWQVISTNAKRVV 216
Query: 177 GYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXX 236
Y Y + Y R+ ++ PS L+ +++ F DA G
Sbjct: 217 SYYKCCPEPYPTVNYYLHIRRRTLYYGFNLIIPSLLISLMAILGFMFPPDA--GEKITLE 274
Query: 237 XXXXXXXXXFTGLRADI-PPVA-YVKALDLWMAGCMMFVFAALGEFVVV 283
F + +++ PP + V + ++ + CM+ V A++ +VV
Sbjct: 275 VTILLAIVFFLSMVSEMTPPTSEAVPLIGVFFSCCMLVVSASVVFTIVV 323
>UniRef50_Q7Z6B2 Cluster: 5-hydroxytryptamine serotonin receptor 3E;
n=30; Theria|Rep: 5-hydroxytryptamine serotonin receptor
3E - Homo sapiens (Human)
Length = 471
Score = 52.4 bits (120), Expect = 2e-05
Identities = 44/216 (20%), Positives = 87/216 (40%), Gaps = 7/216 (3%)
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
NLW PD + + ++ ++ + T K + + +RY M C ++ +P D Q+
Sbjct: 134 NLWLPDIFII--ELMDV-DKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQN 190
Query: 130 CPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN-YS 187
C + SF Y+ + E + +LQ H L + + GN Y
Sbjct: 191 CTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQTHGEWELLGLSKATAKLSRGGNLYD 250
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
++V Y R+ ++I PS +V + SF+L + + G F
Sbjct: 251 QIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPVKS--GNRVPFKITLLLGYNVFL 308
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ +D+ P + + ++ A C+ + +L E + +
Sbjct: 309 LMMSDLLPTSGTPLIGVYFALCLSLMVGSLLETIFI 344
>UniRef50_Q61I41 Cluster: Putative uncharacterized protein CBG10413;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG10413 - Caenorhabditis
briggsae
Length = 366
Score = 52.0 bits (119), Expect = 3e-05
Identities = 50/297 (16%), Positives = 125/297 (42%), Gaps = 15/297 (5%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQT--WSESRLQLPEDIFEEGDDHVTLPPEF 67
P + E ++ + + ++V +++ + + W++ RL + G H+ +P +
Sbjct: 69 PPMTELNLIMAMLKLVDVVEVEEKATFLFDYSAEWTDHRLTW-NPLEYGGISHIYVPQK- 126
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
++W P+ ++ + E S + N TV + A + C+M+ +PMD
Sbjct: 127 --SIWLPEITIADAHEVKFFESEDAPSIAWINFNGTVGFYTSTVASVICEMDVFQFPMDQ 184
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL--LQYHIGQPLRLEETNGYMIDKDGN 185
C + + + +Y + + + P KL ++ + EE +G + N
Sbjct: 185 HECGVSVVANTYFADEYKMNGDMEDMP-KPLSKLGNGEWKVSYIGVKEEKSG-----NEN 238
Query: 186 YSRLVVYF-RFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXX 244
Y +++ RF+R G ++ P+ + LS F+ +++++ + +
Sbjct: 239 YGSTIMFIARFQRNPGFYVALVMVPAFFINFLSIFALFVNVENLSEKITVGLTNIMAMTF 298
Query: 245 XFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESM 301
L AD+P A + L +++ ++ V ++G +++ + K + + +E +
Sbjct: 299 ILVILAADLPKTARIPLLAIYVIVGLVIVMTSIGICLLIPYIRKWRKKRNSSEKEKL 355
>UniRef50_A7RHV9 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 336
Score = 51.2 bits (117), Expect = 5e-05
Identities = 53/281 (18%), Positives = 114/281 (40%), Gaps = 10/281 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP +P V I + ++ + ++IRQ+W L + G +
Sbjct: 27 VRPILDLARPTNVTLDITFNSIIDVDEKHQILSSSVWIRQSWIAETLSWDPAEYG-GVNQ 85
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEI-AELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ + + LW PD N+ E + L + V +Y + V ++ C+++
Sbjct: 86 IVVSSQL---LWQPDTVLYNNIFEEFDSRLDTTVTRVRVYSSGFVYWAMPYVFKTMCKID 142
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTI-NPELKLLQYHIGQPLRLEETNGY 178
+P D Q CPI ++ Y +V ++ T+ + ++ ++ + + Y
Sbjct: 143 VTDFPFDSQRCPITFGAWQYDQNEVNLINNKRLATVASTRVENGEWTVEKVAIERRVIFY 202
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
+ Y + +R+ +++ P+ L+ +L++FSF++ ++ G
Sbjct: 203 QCCPNQPYPEISFVIHMQRRSLFYVVNLVLPNFLITLLAFFSFFIPVEC--GERMSFVIT 260
Query: 239 XXXXXXXFTGLRAD-IPPVA-YVKALDLWMAGCMMFVFAAL 277
F L A+ IPP + V + ++ C++ VF AL
Sbjct: 261 VLLSMTVFLLLVAESIPPTSEAVPVIGVYYTFCIVEVFLAL 301
>UniRef50_Q7T2S3 Cluster: Nicotinic acetylcholine receptor alpha 4
subunit; n=2; Tetraodontidae|Rep: Nicotinic
acetylcholine receptor alpha 4 subunit - Fugu rubripes
(Japanese pufferfish) (Takifugu rubripes)
Length = 622
Score = 50.8 bits (116), Expect = 7e-05
Identities = 43/222 (19%), Positives = 93/222 (41%), Gaps = 7/222 (3%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP V+V F + + + ++ ++ +++++Q W++ +L+ + +E +
Sbjct: 27 RPVENTTDTVLVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWNDYKLRWNPEEYENVTS-I 85
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+P E +W PD N+ + A +TH + L+ + +++ +C ++
Sbjct: 86 RIPSEI---IWRPDIVLYNNADGDFA-VTH-LTKAQLFYDGRIKWMPPAIYKSSCSIDVT 140
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMID 181
+P D QSC + S++Y K+ + V + ++ I + T Y
Sbjct: 141 FFPFDQQSCKMKFGSWTYDRAKIDLISMASDVDQMDYWESGEWVIVNAVGKYNTKKYECC 200
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ YS + YF R + I P L+ L+ F+L
Sbjct: 201 TE-IYSDITYYFIIRRLPLFYTINLIIPCLLISCLTVLVFYL 241
>UniRef50_UPI0001560C7D Cluster: PREDICTED: similar to cholinergic
receptor, nicotinic, alpha 2 (neuronal); n=2;
Laurasiatheria|Rep: PREDICTED: similar to cholinergic
receptor, nicotinic, alpha 2 (neuronal) - Equus caballus
Length = 630
Score = 50.4 bits (115), Expect = 9e-05
Identities = 48/226 (21%), Positives = 91/226 (40%), Gaps = 9/226 (3%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP VIV F + + + ++ ++ +++++Q WS+ +L+ P D
Sbjct: 73 RPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADF--GNITS 130
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ E A +TH + L+ TV + +C ++
Sbjct: 131 LRVPSEM---IWIPDIVLYNNADGEFA-VTH-MTKAHLFSTGTVHWVPPAIYKSSCSIDV 185
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
+P D Q+C + S++Y K+ E V + + ++ I + Y
Sbjct: 186 TFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDYWESGEWAIINATGTYNSKKYDC 245
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
+ Y + YF R + I P L+ L+ F+L D
Sbjct: 246 CAE-IYPDVTYYFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSD 290
>UniRef50_A7RK99 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 446
Score = 50.4 bits (115), Expect = 9e-05
Identities = 46/214 (21%), Positives = 93/214 (43%), Gaps = 17/214 (7%)
Query: 15 FSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHP 74
F + + +N ++ ++ V+ ++ Q W + LQ + + + P E +W P
Sbjct: 58 FVLKITKLNKVDTKNQVISVNAWVFQQWKDPSLQWDKAKYNLHKTRFS-PKE----IWVP 112
Query: 75 DPYFLNS--KVTEIAELTHKFSSVTLYRNQ-TVRYSARMHAIIACQMEFQLYPMDIQSCP 131
D +N+ K+ +A F++ T+ R V + A+ C + + +PMD Q C
Sbjct: 113 DVSLINNGDKLVHVAGGAELFNADTVVRQSGKVDWIAQASFTSTCNLRVRFWPMDDQFCT 172
Query: 132 IYIESFSYSNQKVRFRWSEAGVTI----NPELKLLQYHIGQPLRLEETNGYMIDKDGNYS 187
+ S++Y+ ++ + +G+T N E +L + + L L+ N D N+S
Sbjct: 173 LTFSSWTYTESEIALKMDNSGLTTGHLSNNEWDILNITVKRGL-LDHNNCC----DANFS 227
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSF 221
+ R+ L +P+ ++ LS SF
Sbjct: 228 SVSYTIHMRRKPLFLLFYLASPAVILAALSLASF 261
>UniRef50_P45963 Cluster: Acetylcholine receptor subunit alpha-type
acr-7 precursor; n=2; Caenorhabditis|Rep: Acetylcholine
receptor subunit alpha-type acr-7 precursor -
Caenorhabditis elegans
Length = 538
Score = 50.4 bits (115), Expect = 9e-05
Identities = 62/314 (19%), Positives = 123/314 (39%), Gaps = 16/314 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V +++ V ++ + V+ +++ W++ RL+ + E
Sbjct: 46 VRPVRNPKKALTVTMKVFIQQVLLVDAKHQMIEVNAWLKYIWTDFRLRW-NPLDYENITS 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAE---LTHKFSSVTLYRNQTVRYSARMHAIIACQ 117
V E D +W PD N + + E +T+K ++V Y + + + ++C+
Sbjct: 105 VRFQGE--DQIWQPDILLYNRYIEDEQESFDITYKTNAVA-YSDGVINWIPPGIFKLSCK 161
Query: 118 MEFQLYPMDIQSCPIYIESFSYSNQKVRFR-----WSEAGVTINPELKLLQYH-IGQPLR 171
M+ L+P D Q C + S++Y + R E ++ + ++H + P R
Sbjct: 162 MDITLFPFDEQICFMKFGSWTYHGFALDLRLDVVKGQEPSADLSTYITNGEWHLLSAPAR 221
Query: 172 LEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGR 231
EE Y K+ Y + Y R+ +++ P+ LV +S +F L + +
Sbjct: 222 REE-KFYKCCKE-PYPTVKFYLHLRRRTFYYVFNVVLPTLLVSFMSLLAFCLPATDLSEK 279
Query: 232 XXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
T L P + L + F+ A F ++ VL+ +Y+
Sbjct: 280 IGLQTTILLSVCFFLTILSEMTPTTSEAVPLLGVFFSALTFIVAMSTTFTIL-VLNIRYR 338
Query: 292 MNKNKAQESMPRII 305
N M R I
Sbjct: 339 QITNHYLSPMFRSI 352
>UniRef50_Q4S3I6 Cluster: Chromosome 1 SCAF14749, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 1 SCAF14749, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 340
Score = 50.0 bits (114), Expect = 1e-04
Identities = 33/145 (22%), Positives = 67/145 (46%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP Q V + + + + +N D + ++ Q W + RL PE+ EG
Sbjct: 27 IRPAVNNSQQVTIYIQVSLAQLIHVNERDQIMTTNCWLSQVWYDYRLMWNPEEY--EGIK 84
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ LP + ++W PD N+ E+++ +S+ + N V + AC++E
Sbjct: 85 KIRLPTQ---HIWLPDIVLYNN-ADGTYEVSY-YSNAVISNNGEVNWLPPAIYKSACKIE 139
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+ +P D Q+C + S++Y + ++
Sbjct: 140 VRDFPFDQQNCTLQFRSWTYDHTEI 164
>UniRef50_A7S622 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 299
Score = 50.0 bits (114), Expect = 1e-04
Identities = 35/153 (22%), Positives = 63/153 (41%), Gaps = 7/153 (4%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP P IV F + + + + ++ ++ W L P D G
Sbjct: 17 RPSIESDAPAIVTFRAKLKQIVDLKDNEQLLKIILYNYMQWENPILTWDPRDY--GGVQE 74
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSS-VTLYRNQTVRYSARMHAIIACQME 119
+ + PE +W PD NS + LTHK+ + V + N T + A + CQ++
Sbjct: 75 INVAPE---EVWVPDIVIYNSAEDVLGGLTHKYKTDVVIQANGTNIWLAPAMFLTTCQLD 131
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAG 152
+ +P D Q C + S+++ + ++ R G
Sbjct: 132 VRYFPFDEQKCLLKFGSWTHDSSRLDMRTQTNG 164
>UniRef50_UPI0000F1DA85 Cluster: PREDICTED: similar to MGC52789
protein; n=1; Danio rerio|Rep: PREDICTED: similar to
MGC52789 protein - Danio rerio
Length = 433
Score = 49.6 bits (113), Expect = 2e-04
Identities = 41/164 (25%), Positives = 66/164 (40%), Gaps = 7/164 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP V V ++V + +N + + + W D F G
Sbjct: 53 LRPVDNWKNHVTVYIDLFVTSITEVNEKAQSISTQVLLAHGWGNDFTTWKPDDFC-GMSA 111
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
++ D +W PD S TEIA + + F V L V S + AC+M+
Sbjct: 112 CSVKK---DMVWTPDIVIAESIKTEIATMENAF--VRLESRGIVFASNTLAVTSACKMDL 166
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFR-WSEAGVTINPELKLLQ 163
L+P D QSC + I S +S+ +++ R +S+A K Q
Sbjct: 167 HLFPFDTQSCTLTIMSSVHSSDQLQIRPFSDASFLTQSSQKAFQ 210
>UniRef50_P43681 Cluster: Neuronal acetylcholine receptor subunit
alpha-4 precursor; n=35; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit alpha-4 precursor - Homo
sapiens (Human)
Length = 627
Score = 49.6 bits (113), Expect = 2e-04
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP A V+V F + + + ++ ++ +++++Q W + +L+ P D E
Sbjct: 53 RPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADY--ENVTS 110
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ + A +TH + L+ + V+++ +C ++
Sbjct: 111 IRIPSEL---IWRPDIVLYNNADGDFA-VTH-LTKAHLFHDGRVQWTPPAIYKSSCSIDV 165
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y K+
Sbjct: 166 TFFPFDQQNCTMKFGSWTYDKAKI 189
>UniRef50_O76554 Cluster: Acetylcholine receptor subunit alpha-type
des-2 precursor; n=2; Caenorhabditis|Rep: Acetylcholine
receptor subunit alpha-type des-2 precursor -
Caenorhabditis elegans
Length = 548
Score = 49.6 bits (113), Expect = 2e-04
Identities = 45/226 (19%), Positives = 98/226 (43%), Gaps = 11/226 (4%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
+P +P+ V FS+ + + +N ++ +I + W + L D +E + +
Sbjct: 42 KPMWDNSKPINVSFSMDLYQILELNEPQQYILLNAWIIERWFDEFLYWNPDDYENITE-L 100
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAE----LTHKFSSVTLYRNQTVRYSARMHAIIACQ 117
LP +D++W PD NS V + + L K ++ T R + +C
Sbjct: 101 RLP---YDSIWLPDTTLYNSLVMKDDDTRRLLNSKLTTDTHRRAALIELLYPTIYKFSCL 157
Query: 118 MEFQLYPMDIQSCPIYIESFSYSNQKV-RFRWSEAGVTINPELKLLQYHIGQPLRLEETN 176
++ + +P D+Q C + S++Y + + F +S+ T N Y + ++ +E
Sbjct: 158 LDLRFFPFDVQVCTMTFSSWTYDQKGIDYFPYSDKIGTSNYLENEGWYILQTKIKRQEVK 217
Query: 177 GYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFW 222
+ +L +Y R R+ +L+ P+S++ +++ F+
Sbjct: 218 YACCPNNYTLLQLTLYLR--RKPLFYLVNLIIPTSIITLIAIVGFF 261
>UniRef50_A7S8Q4 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 311
Score = 48.8 bits (111), Expect = 3e-04
Identities = 36/142 (25%), Positives = 67/142 (47%), Gaps = 11/142 (7%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDD-HV 61
P + QP++V+F ++++ +N + V ++RQ W+ S L +F D HV
Sbjct: 13 PMLDRSQPILVKFGFDLINIVDVNAKQQAITVYGWVRQMWNNSLLTWDPALFGGLDILHV 72
Query: 62 TLPPEFFDNLWHPD-PYFLN---SKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQ 117
+ ++W PD F N T T+K + V +Y N T ++ + C+
Sbjct: 73 SA-----KDVWVPDILLFYNVDEQDQTAGGRTTYK-TDVIMYSNGTNKWRSPALLKSICK 126
Query: 118 MEFQLYPMDIQSCPIYIESFSY 139
++ + +P D Q+C + SFS+
Sbjct: 127 IKVKFFPFDSQTCKLKFGSFSH 148
>UniRef50_P36544 Cluster: Neuronal acetylcholine receptor subunit
alpha-7 precursor; n=65; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit alpha-7 precursor - Homo
sapiens (Human)
Length = 502
Score = 48.8 bits (111), Expect = 3e-04
Identities = 66/294 (22%), Positives = 116/294 (39%), Gaps = 23/294 (7%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A QP+ V FS+ ++ + ++ ++ +++++ +W++ LQ + G V
Sbjct: 42 RPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEY-PGVKTV 100
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P +W PD NS H ++V + + +Y +C ++ +
Sbjct: 101 RFPD---GQIWKPDILLYNSADERFDATFH--TNVLVNSSGHCQYLPPGIFKSSCYIDVR 155
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELKLLQYHIGQPLRLEETNGY 178
+P D+Q C + S+SY + + EA G N E L +G P + E Y
Sbjct: 156 WFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDL----VGIPGKRSE-RFY 210
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
K+ Y + R+ ++ + P L+ L+ F L D+ G
Sbjct: 211 ECCKE-PYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADS--GEKISLGIT 267
Query: 239 XXXXXXXFTGLRADIPPVA--YVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY 290
F L A+I P V + + A M+ V G VVV V+ QY
Sbjct: 268 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIV----GLSVVVTVIVLQY 317
>UniRef50_A7RR86 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 479
Score = 48.4 bits (110), Expect = 3e-04
Identities = 32/141 (22%), Positives = 62/141 (43%), Gaps = 5/141 (3%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVT 62
P QP+ V F I + ++ ++ +++RQ WS +RL+ + G V
Sbjct: 50 PIKNHSQPIKVIFDIAFAQLVELDSKNQIMTSYIWVRQFWSNTRLRWDPSKYG-GQTSVN 108
Query: 63 LPPEFFDNLWHPDPYFLNS-KVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
L P +W PD N+ I E+ + V L+ + + A C+++
Sbjct: 109 LSPHL---IWLPDIVLYNNINSNTIGEMFKFDTKVVLHNTGAIEWYAPTLVKSICKIDIT 165
Query: 122 LYPMDIQSCPIYIESFSYSNQ 142
+P D Q+C + S++Y+++
Sbjct: 166 YFPFDKQNCSLVFGSWTYTSE 186
>UniRef50_O46132 Cluster: Nicotinic acetylcholine receptor, alpha1
subunit; n=1; Locusta migratoria|Rep: Nicotinic
acetylcholine receptor, alpha1 subunit - Locusta
migratoria (Migratory locust)
Length = 559
Score = 48.0 bits (109), Expect = 5e-04
Identities = 31/146 (21%), Positives = 68/146 (46%), Gaps = 6/146 (4%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP + V+ + + + +N+++ ++++ Q W++ +L+ D + G D +
Sbjct: 1 RPVTNNSYRLTVKMGLRLSQLIDVNLKNQIMTTNVWVEQEWNDYKLKWNPDDYG-GVDTL 59
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+P E ++W PD N+ E+T + T+Y V + +C+++ +
Sbjct: 60 HVPSE---HIWLPDIVLTNNSEGNF-EVTLA-TKATIYHQGLVEWKPPAIYKSSCEIDVE 114
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFR 147
+P D Q+C + S++Y KV R
Sbjct: 115 YFPFDEQTCVLKFGSWTYDGFKVDLR 140
>UniRef50_A7RLM4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 300
Score = 48.0 bits (109), Expect = 5e-04
Identities = 38/223 (17%), Positives = 93/223 (41%), Gaps = 5/223 (2%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP R P+ + F I + ++ + + IR++W ++ L + FE G
Sbjct: 7 VRPSDRADMPINITFGISLNEIYELTDRTQLLITKVEIRESWVDTSLAWNKSDFE-GLAK 65
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ L PE ++W PD N+ + + + ++V + V + +C+++
Sbjct: 66 IVLRPE---SIWRPDIVLYNNAGEDFGDGQTRTNAVVT-SDGLVSMTIPSILKTSCKIDA 121
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
YP D QSCP+ S++Y + + ++ + +++ + + ++
Sbjct: 122 TRYPFDKQSCPMIFGSWTYDGNLLSIKMESHSADLSEYSENVEWKLVSAEAKFHSKLFVC 181
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
D + + +R+ ++++ P+ + +L+ F L
Sbjct: 182 CPDTPFEEVTYTIVVKRRSLYYIMYLIIPAVAIALLTLLVFLL 224
>UniRef50_Q15822 Cluster: Neuronal acetylcholine receptor subunit
alpha-2 precursor; n=98; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit alpha-2 precursor - Homo
sapiens (Human)
Length = 529
Score = 48.0 bits (109), Expect = 5e-04
Identities = 35/155 (22%), Positives = 68/155 (43%), Gaps = 8/155 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP VIV F + + + ++ ++ +++++Q WS+ +L+ P D
Sbjct: 75 RPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADF--GNITS 132
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ E A +TH + L+ TV + +C ++
Sbjct: 133 LRVPSEM---IWIPDIVLYNNADGEFA-VTH-MTKAHLFSTGTVHWVPPAIYKSSCSIDV 187
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTI 155
+P D Q+C + S++Y K+ E V +
Sbjct: 188 TFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDL 222
>UniRef50_Q2XWL0 Cluster: Nicotinic acetylcholine receptor subunit
type C; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type C - Lymnaea
stagnalis (Great pond snail)
Length = 506
Score = 47.6 bits (108), Expect = 6e-04
Identities = 35/158 (22%), Positives = 73/158 (46%), Gaps = 6/158 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A + + V+ + + V S++ + + +++RQ W + RL+ E G +
Sbjct: 48 IRPSAGPMKKLTVKLGLRLSQVLSVDERNQILTISVWLRQEWYDFRLKWEPS--EYGGVN 105
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V P D LW PD N+ + ++T K ++ + + V ++ C ++
Sbjct: 106 VLNIPS--DQLWKPDLVLYNNADGDF-QITLKTKAIVNHTGRIVWEPPAIYKSY-CPIDV 161
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPE 158
+ +P DIQ C + I S++Y ++ + G+ + E
Sbjct: 162 EYFPFDIQECFLKISSWTYHGHELDLQHLCKGIMSHEE 199
>UniRef50_O61884 Cluster: Acetylcholine receptor protein 23; n=2;
Caenorhabditis|Rep: Acetylcholine receptor protein 23 -
Caenorhabditis elegans
Length = 545
Score = 47.6 bits (108), Expect = 6e-04
Identities = 37/149 (24%), Positives = 65/149 (43%), Gaps = 10/149 (6%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVT 62
P RKG P+ V S+ + + +N ++ + + W + L F D+ T
Sbjct: 44 PKVRKGSPINVTLSLQLYQIIQVNEPQQYLLLNAWAVERWVDQMLGWDPSEF----DNET 99
Query: 63 LPPEFFDNLWHPDPYFLNS-KVTEIA--ELTHKFSSVTLYRNQTVRYSARMHAI--IACQ 117
D++W PD NS ++ + A +LTH TL +NQ I I+C
Sbjct: 100 EIMARHDDIWLPDTTLYNSLEMDDSASKKLTH-VKLTTLGKNQGAMVELLYPTIYKISCL 158
Query: 118 MEFQLYPMDIQSCPIYIESFSYSNQKVRF 146
+ + +P D Q+C + S+S+ N + +
Sbjct: 159 LNLKYFPFDTQTCRMTFGSWSFDNSLIDY 187
>UniRef50_A7RNN1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 317
Score = 47.6 bits (108), Expect = 6e-04
Identities = 50/232 (21%), Positives = 99/232 (42%), Gaps = 13/232 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP V V FS+ + + +N + D+++ Q W L E + G H
Sbjct: 31 VRPVLHPQDAVNVSFSVRLNKLVEVNTKHQLLITDVWVVQKWENPFLVWNESDY--GGVH 88
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIA--ELTHKFSS-VTLYRNQTVRYSARMHAIIACQ 117
TL F D +W PD N+ +++ T KF + + L+ + T + + +C+
Sbjct: 89 -TLHVTFND-VWVPDIVLYNNGDPDLSLSGFTEKFKTFIILHSSGTCTWMSPTTFKSSCK 146
Query: 118 MEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNG 177
++ +P D Q+C + S++Y N+ + + + + + LR ET
Sbjct: 147 LDITKFPFDSQTCSMTFGSWTYDNRLLSMDLLDKQYS---HTERYVENGDWSLRKVETRR 203
Query: 178 YMIDK---DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
Y+++ +S + F +R+ +H++ P ++ LS +F L D
Sbjct: 204 YLLNYTCCPHPFSDVTFTFYLDRKPTYHILYLIVPCVVIAALSVVNFLLPPD 255
>UniRef50_A7RNI2 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 485
Score = 47.6 bits (108), Expect = 6e-04
Identities = 43/227 (18%), Positives = 89/227 (39%), Gaps = 6/227 (2%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP K + + V+F + + ++N +D + ++ RQ W L ++ G +
Sbjct: 43 RPVLNKSEAIEVQFDMAYAQLINLNSKDQILQSKVWFRQRWVNPFLTWDPKMYG-GLTSI 101
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSS-VTLYRNQTVRYSARMHAIIACQMEF 120
+ P +W PD ++ +KF + T+ N + A C ++
Sbjct: 102 NVNPNM---IWKPDIVLYHNIGFGETGAIYKFDTRATIMHNGYTEWFAPTEIHSICAIDI 158
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
+P D Q C + S+SYS +++ ++ K ++ + + Y
Sbjct: 159 TYFPFDEQFCKMKFGSWSYSGRQLNLTSKGDSADLSKYTKSGEWDLLGMRAVRNVVKYSC 218
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
D + + R++ +L AP ++ L+ FSF L L++
Sbjct: 219 CPD-PFIDITFTMHIRRKVLFYLTNLIAPCIVLATLTVFSFQLPLES 264
>UniRef50_A7RLP3 Cluster: Predicted protein; n=3; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 417
Score = 47.6 bits (108), Expect = 6e-04
Identities = 47/216 (21%), Positives = 91/216 (42%), Gaps = 12/216 (5%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
+ FS+ V + + ++ V+ + W S L+ + ++ + V P +W
Sbjct: 38 LNFSLKFVQIMDVKDKEQLVSVECWYSMNWINSFLKWDKKKYQN-ESRVFFDPS---EIW 93
Query: 73 HPDPYFLNS---KVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
PD N+ KV T +++ + +S + C M +P D Q+
Sbjct: 94 VPDIALYNNGDDKVQTSGGRTKFLTNIVVEDTGKCVWSGPVTFTFTCSMALSRWPFDDQN 153
Query: 130 CPIYIESFSYSNQKVRFRWSEAGVTINPE-LKLLQYHIGQ-PLRLEETNGYMIDKDGNYS 187
C + S SY K F S+ V+ + + ++ + + + L+ET+ G +S
Sbjct: 154 CTMKFGSLSYG--KNNFIISKVKVSKSDDFIENSNWELKNITVALQETDHGDCCLFG-FS 210
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
++ R+ +H+ AP L+V+LS FSFW+
Sbjct: 211 QVTYTLNMARKFKYHMFYLVAPCLLMVILSLFSFWI 246
>UniRef50_P46098 Cluster: 5-hydroxytryptamine receptor 3 precursor;
n=50; Tetrapoda|Rep: 5-hydroxytryptamine receptor 3
precursor - Homo sapiens (Human)
Length = 478
Score = 47.6 bits (108), Expect = 6e-04
Identities = 50/295 (16%), Positives = 119/295 (40%), Gaps = 16/295 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 49 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 103
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L ++ ++ + + V + V+ + + AC ++
Sbjct: 104 NITKLSIPTDSIWVPD--ILINEFVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNG 177
+P D+Q+C + S+ ++ Q + + + + L L
Sbjct: 161 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 220
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
+ ++ Y+ + Y R+ +++ PS ++++ F+L ++ G
Sbjct: 221 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS--GERVSFKI 278
Query: 238 XXXXXXXXFTGLRADIPPVAYV--KALDLWMAGCMMFVFAALGEFV-VVKVLDKQ 289
F + +D P + + ++ CM + +L E + +V+++ KQ
Sbjct: 279 TLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 333
>UniRef50_Q4S864 Cluster: Chromosome 5 SCAF14709, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 5
SCAF14709, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 733
Score = 47.2 bits (107), Expect = 8e-04
Identities = 30/145 (20%), Positives = 70/145 (48%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP PVIV+F + + + ++ + ++++R W++ +L+ P++ G +
Sbjct: 192 IRPVENVTDPVIVQFEVSMSQLVKVDEVNQIMETNLWLRHIWNDYKLRWNPKEY--GGVE 249
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++ +P +W PD N+ V + ++ K ++ Y N V + +C+++
Sbjct: 250 YIRVPS---SRIWKPDIVLYNNAVGDF-QVDDKTKALLRY-NGDVTWIPPAIFKSSCKID 304
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y K+
Sbjct: 305 VTYFPFDYQNCTMKFGSWTYDKAKI 329
Score = 44.0 bits (99), Expect = 0.007
Identities = 30/138 (21%), Positives = 66/138 (47%), Gaps = 6/138 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A + + V V+ + + + S+N + ++++ Q W + RL + EG +
Sbjct: 24 IRPAASRSERVPVKLQVSLAQLISVNEREQIMTTNLWLMQHWVDYRLSWDPAKY-EGINK 82
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P +W PD N+ E+T +++ L+ N ++ + AC++E
Sbjct: 83 LRIPSRL---IWLPDIVLYNN-ADGTYEVTVYTNAIVLF-NGSINWLPPAIYKSACKIEV 137
Query: 121 QLYPMDIQSCPIYIESFS 138
+ +P D Q+C + S++
Sbjct: 138 KHFPFDQQNCTLKFRSWT 155
>UniRef50_Q5BW84 Cluster: SJCHGC08361 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC08361 protein - Schistosoma
japonicum (Blood fluke)
Length = 213
Score = 47.2 bits (107), Expect = 8e-04
Identities = 33/149 (22%), Positives = 66/149 (44%), Gaps = 7/149 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V+ SI + + +N + +F+ Q W + L+ E F G+
Sbjct: 27 VRPLKNISEKLTVKISIRLQQIGGLNERNQVLTTILFLEQIWEDDYLKWNESEF--GNVR 84
Query: 61 VTLPPEFFDNLWHPDPY-FLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
P +W PD Y F N+ T L + V ++ + V + + +C+++
Sbjct: 85 TLRIPA--KQVWTPDTYVFNNADHTNSGFLEGIY--VIIHSSGKVSWPIPVQLKTSCKVD 140
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRW 148
L+P D Q+C I S+ Y + + +++
Sbjct: 141 ITLFPFDHQNCEIQFGSWMYKSDWIEYKF 169
>UniRef50_Q2XWK8 Cluster: Nicotinic acetylcholine receptor subunit
type E; n=16; Protostomia|Rep: Nicotinic acetylcholine
receptor subunit type E - Lymnaea stagnalis (Great pond
snail)
Length = 538
Score = 47.2 bits (107), Expect = 8e-04
Identities = 37/170 (21%), Positives = 77/170 (45%), Gaps = 11/170 (6%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP ++V+ I + + I+ ++ ++++RQ W++ +L + G DH
Sbjct: 47 IRPVGNNTDKLVVKMGIRLSQLIDIDEKNQIMTTNVWLRQEWTDKKLTWQASEYG-GVDH 105
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E ++W PD N+ E+T + T++ V + +C +
Sbjct: 106 LYVPSE---HIWLPDIVLYNNADGNY-EVT-LMTKATVHSTGLVVWEPPAIYKSSCTINV 160
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRF-----RWSEAGVTINPELKLLQYH 165
+ +P D QSC + S++Y +V + +EA VTI + L ++
Sbjct: 161 EFFPFDEQSCKMKFGSWTYDGDQVDLVHICAKSNEANVTIKNGIDLRDFY 210
>UniRef50_P04755 Cluster: Acetylcholine receptor subunit beta-like 1
precursor; n=20; Protostomia|Rep: Acetylcholine receptor
subunit beta-like 1 precursor - Drosophila melanogaster
(Fruit fly)
Length = 521
Score = 47.2 bits (107), Expect = 8e-04
Identities = 35/144 (24%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q V V F + V + ++N ++ + ++++R W + +LQ E + G
Sbjct: 43 IRPVQNMTQKVGVRFGLAFVQLINVNEKNQVMKSNVWLRLVWYDYQLQWDEADYG-GIGV 101
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ LPP D +W PD N+ E+ +K S+V +Y V + +C ++
Sbjct: 102 LRLPP---DKVWKPDIVLFNNADGNY-EVRYK-SNVLIYPTGEVLWVPPAIYQSSCTIDV 156
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++++ +V
Sbjct: 157 TYFPFDQQTCIMKFGSWTFNGDQV 180
>UniRef50_UPI0000EBE733 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor alpha6 subunit; n=2; Bos
taurus|Rep: PREDICTED: similar to nicotinic
acetylcholine receptor alpha6 subunit - Bos taurus
Length = 630
Score = 46.8 bits (106), Expect = 0.001
Identities = 40/231 (17%), Positives = 95/231 (41%), Gaps = 17/231 (7%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP P+ V F + + + ++ + ++++R W++ +L+ ++ G +
Sbjct: 54 IRPVENVSDPITVYFEVAITQLADVDEVNQIMETNLWLRHIWNDYKLRWDPTEYD-GIET 112
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ V + ++ K ++ Y + ++ +C M+
Sbjct: 113 LRVPAEM---IWKPDIVLYNNAVGDF-QVKGKTKALLKYDGM-ITWTPPAIFKSSCPMDI 167
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
+P D Q+C + S++Y ++ + I ++ + ++ + + +GY
Sbjct: 168 TFFPFDHQNCSLKFGSWTYDKAEIDL------LIIGSKVDMNEFWENSEWEIVDASGYKH 221
Query: 181 DKDGN-----YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D N Y+ + F R + I P + L+ F+L D
Sbjct: 222 DIKYNCCEEIYTDITYSFYIRRLPMFYTINLIIPCLFISFLTVLVFYLPSD 272
>UniRef50_P54245 Cluster: Uncharacterized acetylcholine
receptor-like protein F18G5.4 precursor; n=2;
Caenorhabditis|Rep: Uncharacterized acetylcholine
receptor-like protein F18G5.4 precursor - Caenorhabditis
elegans
Length = 615
Score = 46.8 bits (106), Expect = 0.001
Identities = 40/222 (18%), Positives = 87/222 (39%), Gaps = 7/222 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP QP V F + + ++ + ++ W + RL E ++ E
Sbjct: 128 VRPCIHHSQPTNVTFGFLLNQIVEMDERNQALTTRSWLNINWMDPRLSWNESLWSE-IKA 186
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEI-AELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P +W PD +N+ + E A L VT N T +SA + +C +
Sbjct: 187 IYIPHA---RIWKPDIILVNNAIREYYASLVSTDVMVTSDGNVTWLFSALFRS--SCPIR 241
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+ YP D Q C + S+S+ ++ + ++ + ++ + + E +
Sbjct: 242 VRYYPFDDQQCDLKFASWSHDITEINLGLNTDKGDLSSYMNNSEFDLVDMTAVREVVTFP 301
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSF 221
D + ++ +V+ R+ ++ P L+ ++ F
Sbjct: 302 SDTNSDWPIIVIRIHMHRRPLFYVFNHIVPCVLISSMAVLGF 343
>UniRef50_UPI00015B4DDF Cluster: PREDICTED: similar to
neurotransmitter gated ion channel; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to neurotransmitter
gated ion channel - Nasonia vitripennis
Length = 461
Score = 46.4 bits (105), Expect = 0.001
Identities = 44/208 (21%), Positives = 89/208 (42%), Gaps = 13/208 (6%)
Query: 20 VDVNSINVEDMD--FRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPY 77
++V ++ V+DM ++++ TW++ +L + G V L +W PD Y
Sbjct: 72 LNVQTVEVDDMTNVMAANVWVVMTWNDDKLTWNSSEYS-GLKQVNLGAH---EIWLPDIY 127
Query: 78 FLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESF 137
LNS + + V+ V + C ++F +P ++ +C + + S+
Sbjct: 128 LLNSAAHGMEYYGDRHCVVS--EQGVVLWVTPTIFHGYCHLDFTFWPFEMNTCRLSLSSW 185
Query: 138 SYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFER 197
+Y +V + +GV ++ + + ++ I Q + Y L F R
Sbjct: 186 TYDGTQVDLKLLTSGVDLDDYVAINEW-IVQNITASRREEVFDCCPEPYVSLDFEFELSR 244
Query: 198 --QIGHHLIQTFAPSSLVVMLSWFSFWL 223
++ +H+I F P+ +V LS +FWL
Sbjct: 245 SSELYYHII--FIPTVPIVFLSLITFWL 270
>UniRef50_Q4RIA9 Cluster: Chromosome 8 SCAF15044, whole genome
shotgun sequence; n=3; Clupeocephala|Rep: Chromosome 8
SCAF15044, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 549
Score = 46.4 bits (105), Expect = 0.001
Identities = 47/228 (20%), Positives = 96/228 (42%), Gaps = 14/228 (6%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQ-LPEDIFEEGDD 59
+RP + V V+ + + + S++ + ++++ Q W + RL +PE+ +G
Sbjct: 20 IRPATNGSELVTVQLMVSLAQLISVHEREQVMTTNVWLTQEWQDYRLTWIPEEF--DGML 77
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
V LP + ++W PD N+ + E++ ++V Y ++ AC++E
Sbjct: 78 KVRLPSK---HIWLPDVVLYNN-ADGVYEVSFYSNAVVSYDGSIFWLPPAIYKS-ACKIE 132
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYH-IGQPLRLEETNGY 178
+ +P D Q+C + S++Y ++ +++ ++ I P R E G
Sbjct: 133 VKHFPFDQQNCTLRFRSWTYDRTEIDLVLRADVASMDDFTPSGEWDIIALPGRRNENPG- 191
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D Y + F R+ + I P L+ L+ F+L D
Sbjct: 192 ----DPTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSD 235
>UniRef50_Q2XWK6 Cluster: Nicotinic acetylcholine receptor subunit
type G; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type G - Lymnaea
stagnalis (Great pond snail)
Length = 618
Score = 46.4 bits (105), Expect = 0.001
Identities = 45/226 (19%), Positives = 90/226 (39%), Gaps = 7/226 (3%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP V V+F + +V ++ ++ + +++++ Q W + RL E + H+
Sbjct: 104 RPVMNASLSVQVKFGLTLVQISDMDEVNQVLTINVWLEQEWVDERLTWSPK--EYNNLHI 161
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P + LW PD NS + + S + N TV + +C+++
Sbjct: 162 LRIP--CEKLWLPDIVLYNS--ADDYTTGYMNSKAMVQHNGTVFWPPPAKFRSSCKIDIT 217
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMID 181
+P D Q+C + S++Y +V A V + + ++ + +R+ T
Sbjct: 218 YFPFDDQTCELKFGSWTYDGFQVDITNRSATVDLQNYVFSGEWEL-MDVRIRRTEVTYAC 276
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
Y + R+ ++L P + +LS FWL D+
Sbjct: 277 CIEPYPDVRFTIVIRRKTLYYLFNIIFPCLWLTILSLLGFWLPPDS 322
>UniRef50_Q4RU50 Cluster: Chromosome 1 SCAF14995, whole genome
shotgun sequence; n=3; Tetraodontidae|Rep: Chromosome 1
SCAF14995, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1044
Score = 46.0 bits (104), Expect = 0.002
Identities = 42/174 (24%), Positives = 73/174 (41%), Gaps = 8/174 (4%)
Query: 52 DIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMH 111
D E G V+LP E LW PD + + + T V +Y V + +
Sbjct: 19 DAEECGTQRVSLPRE---KLWIPDIHITEFMDEDKSPRT---PYVYIYNTGHVFDDSPLR 72
Query: 112 AIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVR-FRWSEAGVTINPELKLLQYH-IGQP 169
+ C++ +P DIQ+C + S+ + + ++ F + A + L + Q +
Sbjct: 73 VVSTCKLGIYSFPFDIQNCSLTFGSYIHFDTDIQMFASTTAAEILEESLSVAQTKGEWEL 132
Query: 170 LRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ ++ + DG YS+L Y R+ ++I PS +V L FSF L
Sbjct: 133 INIQVFPSVLEITDGKYSQLKYYLILRRRPILYVINLILPSIFLVTLDVFSFLL 186
>UniRef50_Q9UGM1 Cluster: Neuronal acetylcholine receptor subunit
alpha-9 precursor; n=30; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit alpha-9 precursor - Homo
sapiens (Human)
Length = 479
Score = 46.0 bits (104), Expect = 0.002
Identities = 43/224 (19%), Positives = 97/224 (43%), Gaps = 9/224 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V I + + ++ + ++IRQ W ++ L D ++ G D
Sbjct: 46 LRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYD-GLDS 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N E +E + ++V L + + + A +C ++
Sbjct: 105 IRIPS---DLVWRPDIVLYNKADDESSEPVN--TNVVLRYDGLITWDAPAITKSSCVVDV 159
Query: 121 QLYPMDIQSCPIYIESFSYS-NQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+P D Q C + S++Y+ NQ F ++G ++ ++ +++ + ++ Y
Sbjct: 160 TYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSG-DLSDFIEDVEWEVHGMPAVKNVISYG 218
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ Y + +R+ +++ P L+ L+ SF+L
Sbjct: 219 CCSE-PYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYL 261
>UniRef50_UPI00015A4976 Cluster: 5-hydroxytryptamine receptor 3
subunit C; n=2; Danio rerio|Rep: 5-hydroxytryptamine
receptor 3 subunit C - Danio rerio
Length = 410
Score = 45.6 bits (103), Expect = 0.002
Identities = 60/286 (20%), Positives = 113/286 (39%), Gaps = 19/286 (6%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP P V + + + +N + +++R W L D E G +
Sbjct: 1 RPVISLKTPTNVTVDLTLYGILGVNEKSQVLETYLWVRTRWQIEGLTW--DPAECGTKKI 58
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+LP E +W PD +N + E + VT Q + H I +C+++
Sbjct: 59 SLPRE---KIWFPD-IVINEFMDENRAPDTYYVYVTS-TGQVID-GRPFHIISSCKLDIY 112
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMID 181
+P D Q+C S+ +S V+ + + I E L G+ ++ M+
Sbjct: 113 TFPFDFQNCTYTFNSYKHSRDDVQLFFYKPVKDIFKESLDLMTTKGEWELID-----MLA 167
Query: 182 KDGNYSRLVVYFR--FERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
+ YS L+ +F+ R+ +++ PSS ++ L FSF L +
Sbjct: 168 EKPVYSFLLRHFQIVLRRRATLYVVNLLIPSSFLLSLDIFSFLLPPQTVD--RASFKMTL 225
Query: 240 XXXXXXFTGLRADIPPVA--YVKALDLWMAGCMMFVFAALGEFVVV 283
F L D+ PV + ++++ + C+ + A+L E +V+
Sbjct: 226 ILGYTVFLLLMNDLLPVTGNNLPLINVFFSMCLALMVASLLETIVI 271
>UniRef50_O95264 Cluster: 5-hydroxytryptamine 3B receptor precursor;
n=13; Theria|Rep: 5-hydroxytryptamine 3B receptor
precursor - Homo sapiens (Human)
Length = 441
Score = 45.6 bits (103), Expect = 0.002
Identities = 39/224 (17%), Positives = 96/224 (42%), Gaps = 8/224 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V ++V + ++ E+ + ++ ++ W++ L +F+E +
Sbjct: 47 VRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWNSSMFDEIRE- 105
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
++LP +W PD + ++ +I E V + + T+ + + AC +E
Sbjct: 106 ISLP---LSAIWAPD--IIINEFVDI-ERYPDLPYVYVNSSGTIENYKPIQVVSACSLET 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELK-LLQYHIGQPLRLEETNGYM 179
+P D+Q+C + +S ++ + V + + I + K L + L + T +
Sbjct: 160 YAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWELLSVSSTYSIL 219
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
G ++++ R +++ PS ++++ SF+L
Sbjct: 220 QSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYL 263
>UniRef50_UPI0000E47621 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor subunit type G, partial; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor subunit type G, partial
- Strongylocentrotus purpuratus
Length = 283
Score = 44.8 bits (101), Expect = 0.004
Identities = 46/229 (20%), Positives = 94/229 (41%), Gaps = 10/229 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP + + V+ + +V++ ++ + + F+ Q W+++ LQ P + + D
Sbjct: 28 VRPVMYQEDTITVKIDLAIVNLLDMDEANQIMTANTFMTQEWNDAFLQWEPSESWNITDV 87
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
V + +N+W PD L++ + +++ + + TV + + AC M
Sbjct: 88 QVPI-----NNIWRPD-IILHNNANDELNGGIRWTHAWIRYDGTVTWKTNYILMSACPMN 141
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVR-FRWSEAGVTINPELKLLQYHIGQPLRLEETNGY 178
+P D Q+C + + S++Y+ ++ S +G + I PLR E
Sbjct: 142 PLYFPFDTQNCSLKLGSWTYNEDEINVIANSTSGDATQYQPNGEWDLIDFPLRREVDVRQ 201
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
G Y ++ +RQ + P ++ L SF L DA
Sbjct: 202 CC--PGAYPSVIFNVIIKRQFLFYFFNLVVPCVIISSLVLLSFVLPSDA 248
>UniRef50_UPI00015A3E3C Cluster: Neuronal acetylcholine receptor
subunit alpha-4 precursor.; n=1; Danio rerio|Rep:
Neuronal acetylcholine receptor subunit alpha-4
precursor. - Danio rerio
Length = 556
Score = 44.8 bits (101), Expect = 0.004
Identities = 59/291 (20%), Positives = 113/291 (38%), Gaps = 25/291 (8%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQ-LPEDIFEEGDDH 60
RP V V F + + + ++ ++ +++++Q W + RL+ PED
Sbjct: 46 RPVHSVSDVVHVHFGLSIAQLIDVDEKNQMMTTNVWVKQEWLDYRLRWTPED--NGNVSS 103
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P +F +W PD N+ + +TH + L+ + ++ +C ++
Sbjct: 104 MRIPAQF---IWKPDIVLYNNADGDFT-VTHLTKAHLLHDGRVTWIPPAIYKS-SCSIDV 158
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQY-HIGQPLRLEETNGYM 179
P D Q+C I S++Y K+ + I + L Y G+ L Y
Sbjct: 159 TFLPFDQQNCTIKFGSWTYDRSKIDL------IRIADSVDQLDYWESGEWLITSAVATYN 212
Query: 180 IDK----DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXX 235
+ K Y+ + F R + I P L++ L+ F+L D G
Sbjct: 213 VKKYECCSEEYADITYSFIIRRLPLFYTINLIIPCLLILCLTVLVFYLPSDC--GEEVTM 270
Query: 236 XXXXXXXXXXFTGLRAD-IPPVAYVKALDLWMAGCMMFVFAALGEFVVVKV 285
F L + IPP + V L +A ++F+ + F+++ V
Sbjct: 271 CISVLLSLTVFLLLITEIIPPTSLVIPL---IAEYLLFIMIFIILFIIITV 318
>UniRef50_Q9GP98 Cluster: Acetylcholine receptor protein 22; n=3;
Caenorhabditis|Rep: Acetylcholine receptor protein 22 -
Caenorhabditis elegans
Length = 434
Score = 44.8 bits (101), Expect = 0.004
Identities = 42/210 (20%), Positives = 88/210 (41%), Gaps = 15/210 (7%)
Query: 11 VIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDN 70
V V+ IY ++ +N ++ ++ ++ Q+W + L + G + + +P
Sbjct: 63 VTVQPQIY--NLVEVNEQNEQIKILLWFPQSWKDDYLTWDPKEWN-GIERIIIPKS---Q 116
Query: 71 LWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSC 130
+W PD Y N+ V E L + + V V ++ + + C M +P D+Q C
Sbjct: 117 IWIPDGYIFNT-VEETEPLENHNARVRYDGRVEVDFNKLVD--LTCPMSVLSFPFDVQLC 173
Query: 131 PIYIESFSYSNQKVRFRWSEAGV---TINPELKLLQYHIGQPLRLEETNGYMIDKDGNYS 187
+ S+SY + F + V + N E ++ ++ ++ G + Y
Sbjct: 174 ALQFGSWSYQAHAISFNVLDTFVPKKSKNSEWDIVSFN---ATKMTTKYGDTLGGFNVYE 230
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLS 217
+ Y R+ ++++ PS L+V +S
Sbjct: 231 EIFYYLELRRKPLYYIVVILLPSFLIVTVS 260
>UniRef50_Q65XS8 Cluster: Acetylcholine receptor protein 25; n=2;
Caenorhabditis elegans|Rep: Acetylcholine receptor
protein 25 - Caenorhabditis elegans
Length = 544
Score = 44.8 bits (101), Expect = 0.004
Identities = 66/335 (19%), Positives = 127/335 (37%), Gaps = 22/335 (6%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP + V+V+ + + + ++ ++ V+ +++ +W + L+ PED D
Sbjct: 42 RPIENSSEAVMVKMGLVLQQIVDVDEKNQVVDVNAWLKFSWVDYSLKWKPEDYGGVTDLR 101
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
LW PD NS + + S++ +Y N V + ++C+++
Sbjct: 102 FRK-----GQLWTPDVLMYNSADPQFD--SRYASNLLVYPNGLVNWMPPGLYRLSCKIQV 154
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
+P D+Q C + S+++ K+ + G I+ ++ ++ + Y
Sbjct: 155 VWFPFDVQECFLKFGSWTFDGTKLNLEIDDNGFDISNYMQNGEWTLEGTTVKRNIQYYQC 214
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
+ Y LV F R+ ++ P L+ ML+ F DA G
Sbjct: 215 CPEPYYD-LVFTFVIRRRALYYAFNLILPCILITMLTLVGFTFPPDA--GEKMSLQITIM 271
Query: 241 XXXXXFTGLRADI-PPVA-YVKALDLWMAGCMMFVFAALGEFVVVKV-----LDKQYQMN 293
F A++ PP + V L + A C +F A + + K +QMN
Sbjct: 272 LSICIFQNYVAELSPPTSEAVPFLSAFFAVC-LFTCACCVTATTLALNFHHRTGKSHQMN 330
Query: 294 KN---KAQESMPRIIPVRLNGDKGSCGTIAAWEGS 325
E +P ++ +R G CG I + S
Sbjct: 331 NTFRLLMLEWIPWLLMMRRPGYVARCGKIVKQDDS 365
>UniRef50_UPI0000F1E62D Cluster: PREDICTED: hypothetical protein;
n=1; Danio rerio|Rep: PREDICTED: hypothetical protein -
Danio rerio
Length = 357
Score = 44.4 bits (100), Expect = 0.006
Identities = 40/173 (23%), Positives = 73/173 (42%), Gaps = 10/173 (5%)
Query: 55 EEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAII 114
E G D ++LP + LW PD A +T+ + + N V H I
Sbjct: 78 ECGTDRISLPRK---QLWMPDIVINEFMDENKAPVTYY---LYVQHNGMVMDDRPTHVIS 131
Query: 115 ACQMEFQLYPMDIQSCPIYIESFS-YSNQKVRFRWSEAGVTINPELKLLQYH-IGQPLRL 172
+C M+ +P DIQ+C S+ +++ + E VT+ L +++ + + L
Sbjct: 132 SCIMDIYTFPFDIQNCTFTFNSYKLFASDIQMLFFEEVEVTLANSLAVMKTKGEWELVNL 191
Query: 173 EETNGYMIDKDGN--YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
++ +D N + L+ Y R+ +++ PS ++ L FSF L
Sbjct: 192 LAEKPFIPPEDLNNTFDTLIYYIALRRRPTMYVVNLLIPSCFLIALDLFSFLL 244
>UniRef50_UPI000069F132 Cluster: 5-hydroxytryptamine receptor 3
subunit D; n=3; Euteleostomi|Rep: 5-hydroxytryptamine
receptor 3 subunit D - Xenopus tropicalis
Length = 415
Score = 44.4 bits (100), Expect = 0.006
Identities = 33/144 (22%), Positives = 61/144 (42%), Gaps = 7/144 (4%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP P +V SI V + +N +D +++ W + E G ++
Sbjct: 1 RPVRDLNHPTVVNISITVYAILGVNEKDQLLTSFLWLTMVWFNEFAEW-EPALCGGVQNI 59
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
++P E +W PD + L V E + + + + N VR+ + + +C +
Sbjct: 60 SVPAE---EMWIPDIFVLQF-VDE--DKSPHLPYLLVDHNGRVRFLKPLRVVSSCNLSIF 113
Query: 122 LYPMDIQSCPIYIESFSYSNQKVR 145
+P DIQ+C + SF S + +R
Sbjct: 114 RFPFDIQNCTLTFGSFLDSGRDIR 137
>UniRef50_A7S9T8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 390
Score = 44.4 bits (100), Expect = 0.006
Identities = 40/190 (21%), Positives = 83/190 (43%), Gaps = 8/190 (4%)
Query: 35 DMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFS 94
++++RQTW+++ L+ + G + + P F LW PD N+ E + F+
Sbjct: 10 NVWVRQTWTDAWLKW-DPAKHGGITAINVDPSF---LWKPDMVLYNNVNDEDRGEQYLFN 65
Query: 95 S-VTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQK--VRFRWSEA 151
+ V +Y + + + C+++ Q +P D Q+C + S++Y+ K V F A
Sbjct: 66 TKVIIYSTGDIEWYSPNILKTHCKIDIQYFPFDTQTCKLTFGSWTYNGLKIDVTFFRGIA 125
Query: 152 GVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSS 211
G I+ + ++ + + Y + Y L + +R+ ++ P
Sbjct: 126 GADISTYSQNGEWELVSADAVRNVVKYSCCPE-PYQDLTYKIKIKRRSMFYVNNLILPCI 184
Query: 212 LVVMLSWFSF 221
L+ +L+ SF
Sbjct: 185 LLALLTGLSF 194
>UniRef50_A7S2P0 Cluster: Predicted protein; n=4; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 541
Score = 44.4 bits (100), Expect = 0.006
Identities = 54/262 (20%), Positives = 101/262 (38%), Gaps = 10/262 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP K V V+ + + + + + V +++RQ W + + + G
Sbjct: 84 LRPVLSKTHNVTVKLGLTLNQIMDVIEKFELLSVSLYVRQKWENPLVAWNKSEYG-GIVQ 142
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSS-VTLYRNQTVRYSARMHAIIACQME 119
V L P LW PD Y N+ + + F++ + + + T + A +C++
Sbjct: 143 VNLDPS---TLWKPDIYLYNNADSGYDGSLYGFTAKIKVNYSGTNTWLAPKIFTTSCKIN 199
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQY-HIGQPLRLEETNGY 178
+ +P D Q C + S++Y V E +I K ++ IG P + Y
Sbjct: 200 VKYFPFDQQECRLKFGSWTYDANSVDIFPEEDQASIKGYQKNGEWDFIGFPCK-RSILYY 258
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
D ++ + R+ ++ + P L+ +LS SF + D+ G
Sbjct: 259 PCCPDSPFTDVTCTLIIRRKTLYYWVNLIIPCMLITVLSLLSFIVSTDS--GERVGLVIT 316
Query: 239 XXXXXXXFTGLRADI-PPVAYV 259
F + ADI PP + V
Sbjct: 317 DLLALTVFMLIVADILPPTSEV 338
>UniRef50_A7RS32 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 325
Score = 44.4 bits (100), Expect = 0.006
Identities = 47/220 (21%), Positives = 97/220 (44%), Gaps = 14/220 (6%)
Query: 7 KGQPVIVEFSI-YVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPP 65
KG PV ++ ++ ++DVN V +++RQ W + RL+ ++ G D++ +
Sbjct: 36 KGVPVRLDLALNQIIDVNK---RAQTMTVVIWVRQYWRDPRLRWNVSAYD-GVDNIVIKA 91
Query: 66 EFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLY-RNQTVRYSARMHAIIACQMEFQLYP 124
LW PD N+ + S+T+ R R+ ++ +C + + +P
Sbjct: 92 S---RLWLPDITLYNNARDDYKLDKESQHSLTITSRGGVSRFFPTIYKS-SCALNIRHFP 147
Query: 125 MDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYMIDKD 183
D Q+C + + S+SY+ +V + +N + ++ + G P ET
Sbjct: 148 FDDQTCILKLGSWSYNVFEVNLT-NVGNGDLNSFISNGEWVLKGMPAERHETKFRCCPHP 206
Query: 184 GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
Y L+ R+ +++I F P +++ L++ F+L
Sbjct: 207 --YIFLLYKINIRRRSLYYVINCFTPCLIMLALTFLGFYL 244
>UniRef50_UPI0000E49087 Cluster: PREDICTED: similar to Glra4a
protein; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to Glra4a protein -
Strongylocentrotus purpuratus
Length = 541
Score = 44.0 bits (99), Expect = 0.007
Identities = 53/294 (18%), Positives = 109/294 (37%), Gaps = 24/294 (8%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P Q V ++ V I+ F ++++ TW E +++ + D+H
Sbjct: 110 PREDKQKVFARIRCNIITVGDIDTVAQLFTAEIYLSVTWKEPKVKGMKREDVNWDEH--- 166
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKF---SSVTLYRNQTVRYSARMHAIIACQMEF 120
W P YF N+ + + H VR S RM C M+
Sbjct: 167 --------WDPRIYFFNAVNIDKMQTNHYIMPNDDDDPDGIPDVRLSIRMKGTFKCSMQL 218
Query: 121 QLYPMDIQSCPIY------IESFSY-SNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLE 173
+ +P D Q I +E + + ++ T + KL ++ + QP+
Sbjct: 219 KDFPFDCQDLTIKLMSDWPVEDVEFVKDMNIKDSIRLDTFTAGHQWKLWKHVLAQPI--- 275
Query: 174 ETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXX 233
E + + +Y + +R+ G ++ L+V+L++ SF ++ A R
Sbjct: 276 EEDKALTGAHRSYPIYHITTHVQRRPGFYIWNIALIMLLIVILTFTSFVVERGAPADRLS 335
Query: 234 XXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLD 287
+ +P ++Y+ LD ++ C++F +G+ + V++
Sbjct: 336 VTVTLLLTAVAFKYVVSQSLPLISYLTMLDKYVLSCLIFQCLVVGQNALSAVVE 389
>UniRef50_UPI0000E473D1 Cluster: PREDICTED: similar to neuronal
acetylcholine receptor subunit alpha-9 precursor; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
neuronal acetylcholine receptor subunit alpha-9
precursor - Strongylocentrotus purpuratus
Length = 510
Score = 44.0 bits (99), Expect = 0.007
Identities = 47/227 (20%), Positives = 97/227 (42%), Gaps = 14/227 (6%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V+V F + + V + ++ + RQ W + LQ D + G +
Sbjct: 114 IRPVNNASKTVVVSFRVLISQVILFDERKQHVQLSGWRRQDWRDEFLQWDPDDYG-GLET 172
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSS-VTLYRNQTVRYSARMHAIIACQME 119
+T D +W PD + + V + + ++FS+ V + + +V + + AC +
Sbjct: 173 ITFSK---DGIWKPDITLIEN-VNQ--DFINEFSADVIVTYDGSVTWFTPIILTSACMVG 226
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL-LQYHIG--QPLRLEETN 176
+ +P D Q+C + S++Y + + + + +P + LQ + Q + N
Sbjct: 227 VRYFPFDFQTCQMTYMSWAYDSNGI---YLQLPTNEDPNQSVFLQNGVWSLQNSVAHQKN 283
Query: 177 GYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ YS++V ER G +++ PS L+ ++ F L
Sbjct: 284 ETYACCETPYSQIVYELILERSYGFYVLNIVLPSGLLAFVNCLVFLL 330
>UniRef50_Q9N5U8 Cluster: Acetylcholine receptor protein 21; n=2;
Caenorhabditis|Rep: Acetylcholine receptor protein 21 -
Caenorhabditis elegans
Length = 469
Score = 44.0 bits (99), Expect = 0.007
Identities = 41/228 (17%), Positives = 88/228 (38%), Gaps = 8/228 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP +P+ V F + + ++ + + +IR W + +L +++
Sbjct: 15 VRPSVHSKEPINVTFVFSLTQIIDVDERNQILTTNSWIRLHWVDYKLVWDPRLYQNVT-R 73
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N+ + + + Y + + +C ++
Sbjct: 74 IHIPS---DKIWKPDIILYNNADAQYMKSVMSTDVIVDYLGN-IHWPLSAIFTSSCPLDV 129
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+ YP D Q+C + S++Y K+ SE G N IG +R E+
Sbjct: 130 KHYPFDRQTCILKYASWAYDGTKIDLLLKSEQGDLTNYITNTEWSLIG--IRAEKNQVIY 187
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
Y + V+ ER+ ++ P L+ +++ F++ D+
Sbjct: 188 SCCPEPYPFIDVHVTIERRAMFYVFNLILPCVLISLIALMGFYMPTDS 235
>UniRef50_Q6Q069 Cluster: Neuronal nicotinic acetylcholine Apisa7-2
subunit; n=3; Apis mellifera|Rep: Neuronal nicotinic
acetylcholine Apisa7-2 subunit - Apis mellifera
(Honeybee)
Length = 461
Score = 44.0 bits (99), Expect = 0.007
Identities = 31/159 (19%), Positives = 69/159 (43%), Gaps = 10/159 (6%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP QP+ V F + + + ++ ++ + ++ Q W++ L+ F G
Sbjct: 21 VRPAENSSQPLAVVFGLSLHHIIDVDEKNQILTTNCWVTQIWTDHHLKWNASEF-AGIRV 79
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAII--ACQM 118
+ +P ++ +W PD N+ + + + + + + V S H I +C +
Sbjct: 80 IRVP---YNRVWRPDTILYNNADPQYSSAVINTNVIVSHTGEVVWLS---HGIFRSSCDI 133
Query: 119 EFQLYPMDIQSCPIYIESFSYSNQKVRF-RWSEAGVTIN 156
+ + +P D Q C + S++Y ++ + SE G N
Sbjct: 134 DVEFFPFDEQRCVLKWASWTYDGYQLELEKQSEQGDVSN 172
>UniRef50_UPI0000E49402 Cluster: PREDICTED: similar to alpha 10
subunit of nicotinic acetylcholine receptor; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
alpha 10 subunit of nicotinic acetylcholine receptor -
Strongylocentrotus purpuratus
Length = 473
Score = 43.2 bits (97), Expect = 0.013
Identities = 59/313 (18%), Positives = 123/313 (39%), Gaps = 22/313 (7%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIR------QTWSESRLQL-PEDI 53
+RP R P+ V + + ++ ++ +++++R Q W++S L+ P D
Sbjct: 33 IRPVERSADPIDVLIGAAIQQIIDMDEKNQVITLNLWMRMHFLFIQQWTDSNLKWNPADY 92
Query: 54 FEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAI 113
GD V + P + +W PD + + + +S ++ + VR++A
Sbjct: 93 ---GDTTVLIVP--IETIWRPDIVLFTNADSSFNGMM--MTSASISHDGIVRWNAPAIYQ 145
Query: 114 IACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYH-IGQPLRL 172
C+++ +P D Q C + S++Y ++ + I+ + ++ +G P++
Sbjct: 146 STCKIDITYFPFDEQHCSLKFGSWAYHGFQIDLKNRTTSGDISAYIDNGEWTLVGMPVKR 205
Query: 173 EETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRX 232
+ V R R+ + I P L+ +++ F++ DA G
Sbjct: 206 NLLFYNCCPEPYPDVEFTVIIR--RRALFYFINLLGPCVLISLITVLDFFMPADA--GEK 261
Query: 233 XXXXXXXXXXXXXFTGLRAD-IPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
F L A+ +PP + V L C + V +L + V VL Y+
Sbjct: 262 VTLGITILLALTVFLLLVAETMPPTSEVVPLIAQYYACTI-VLVSLSTVMTVYVLSLHYR 320
Query: 292 M-NKNKAQESMPR 303
+ N+ M +
Sbjct: 321 LPGTNRVPRGMKK 333
>UniRef50_UPI0000D55EDD Cluster: PREDICTED: similar to CG11822-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG11822-PA, isoform A - Tribolium castaneum
Length = 438
Score = 43.2 bits (97), Expect = 0.013
Identities = 37/191 (19%), Positives = 79/191 (41%), Gaps = 8/191 (4%)
Query: 34 VDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKF 93
V +IR +W + +LQ + G + + L +W PD + NS + + +TH
Sbjct: 86 VHSWIRLSWKDEKLQWNSTNYG-GLETLNLADH---EIWQPDIFLYNSATS--SGITHYG 139
Query: 94 S-SVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAG 152
+ + +Y V + + C + + +P D Q C + S++Y+ ++ G
Sbjct: 140 NVNCIVYEGGDVLWVPPAQFSVLCNLNLKYWPFDTQRCEMIFGSWTYNGDQIDIDPDNDG 199
Query: 153 VTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSL 212
V + ++ +++I L++ Y Y + + R + P+ +
Sbjct: 200 VKMELLIENSEWNIVDK-SLKKNMKYYACCPSPYPDITIDLTLSRISPSYKALIVTPAFV 258
Query: 213 VVMLSWFSFWL 223
V++L +FWL
Sbjct: 259 VIILVLVNFWL 269
>UniRef50_Q67X94 Cluster: Putative uncharacterized protein lgc-2;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein lgc-2 - Caenorhabditis elegans
Length = 509
Score = 43.2 bits (97), Expect = 0.013
Identities = 32/137 (23%), Positives = 62/137 (45%), Gaps = 8/137 (5%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
VE+ + +V + I+ V +++ + W + L +F G +P D +W
Sbjct: 90 VEYELELVHILGIDELKQTMTVLIYVDEHWVDPSLTWDPALFG-GITKTWIP---LDKIW 145
Query: 73 HPDPYFLNS-KVTEIAE---LTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
PD N K +A L+ + ++ N T+ S ++C++ + +P+D Q
Sbjct: 146 VPDIIVFNMVKSNRLAHEDLLSAVRAPARIHYNGTIVASHPAVHTVSCEINIRHFPLDDQ 205
Query: 129 SCPIYIESFSYSNQKVR 145
C I I S++Y +K+R
Sbjct: 206 RCAIEIASWAYGQEKIR 222
>UniRef50_Q2XWL1 Cluster: Nicotinic acetylcholine receptor subunit
type B; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type B - Lymnaea
stagnalis (Great pond snail)
Length = 527
Score = 43.2 bits (97), Expect = 0.013
Identities = 41/225 (18%), Positives = 93/225 (41%), Gaps = 10/225 (4%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP + + +++ + ++ + ++ + +++ +W + L E E G+ +
Sbjct: 49 RPVQEQSDKITIKYGMSLIQIVDLDERNQILTTNVWPTYSWIDMYLAWNES--EYGN--I 104
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
T D++W PD N T + E + + L N V + + +C ++ +
Sbjct: 105 TTVRVNNDDIWKPDIKLYNYADTRLEE--KREALCVLSSNGEVVWIPQAVFKSSCSIDIR 162
Query: 122 LYPMDIQSCPIYIESFSYSNQK--VRFRWSEA-GVTINPELKLLQYHIGQPLRLEETNGY 178
+P D+Q C + S++Y K ++FR+ + G ++ + ++ I + Y
Sbjct: 163 HFPFDVQRCDMKFGSWTYDGSKLDIQFRYPDVKGFEMDDYIVSNEWDIVESNAKRNVKYY 222
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ + Y LV R++ + P L+ L+ FWL
Sbjct: 223 LCCPE-PYVDLVFSLTIRRKVAFYSYILILPCVLLSSLTLVLFWL 266
>UniRef50_O61216 Cluster: Ligand-gated ion channel protein 30; n=3;
Caenorhabditis|Rep: Ligand-gated ion channel protein 30
- Caenorhabditis elegans
Length = 529
Score = 43.2 bits (97), Expect = 0.013
Identities = 33/194 (17%), Positives = 85/194 (43%), Gaps = 5/194 (2%)
Query: 34 VDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKF 93
V ++ W++ ++ +IF G + + +P ++ +W P+ Y +S + +
Sbjct: 113 VSAYLDVHWNDDFIKWKPEIFG-GIERIFVPIKW---IWKPEFYMYHSVYGRVPDYAPD- 167
Query: 94 SSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGV 153
+S L+ N VR + + C + F+ +P D Q+C S++Y + V ++ +
Sbjct: 168 ASAELHYNGLVRMFVSISSKSFCPINFKRFPFDSQTCSFSCGSWAYQSNIVNLVAAKQEI 227
Query: 154 TINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLV 213
+ ++ + T + + ++S + + +RQ +++ P++LV
Sbjct: 228 ALEDFYDNQEWLLTDARLFNGTTRNVSAANESFSMVYMQLDLKRQSFYYVFNLVFPTTLV 287
Query: 214 VMLSWFSFWLDLDA 227
+++ F ++A
Sbjct: 288 SLVAVIGFHAPINA 301
>UniRef50_A7I712 Cluster: Putative uncharacterized protein
precursor; n=1; Candidatus Methanoregula boonei 6A8|Rep:
Putative uncharacterized protein precursor -
Methanoregula boonei (strain 6A8)
Length = 337
Score = 43.2 bits (97), Expect = 0.013
Identities = 45/216 (20%), Positives = 87/216 (40%), Gaps = 8/216 (3%)
Query: 80 NSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSY 139
N + ++ + +SV+ + R++A + + + YP D + PI IE
Sbjct: 96 NISINDLEFMNGHATSVSTITDTPGEKDYRVYAEMTANPDLRRYPFDNHTLPIIIEPTIL 155
Query: 140 SNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQI 199
+ + + F ++ E L + + + E TN ++ + YSR+ ER
Sbjct: 156 TEKDLVFVIDGNNTGLDDEANLPGWSL-TGMSAEVTNRTYVEGEVPYSRVTFSNGIERDT 214
Query: 200 GHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYV 259
L++ F P +L++++S S + + R + IP VAY
Sbjct: 215 ASTLLKFFLPITLIIIVSLASLLMKTSS---RLGLNGSMFLAAVLIHWRIADAIPLVAYA 271
Query: 260 KALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKN 295
LDL+ M+ +A L V +L ++ +KN
Sbjct: 272 TFLDLF----MIITYATLVMVCVSGILLLKFTEDKN 303
>UniRef50_P17787 Cluster: Neuronal acetylcholine receptor subunit
beta-2 precursor; n=69; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit beta-2 precursor - Homo
sapiens (Human)
Length = 502
Score = 43.2 bits (97), Expect = 0.013
Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V V+ + + + S++ + ++++ Q W + RL + F+
Sbjct: 46 IRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKK- 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V LP + ++W PD N+ + E++ ++V Y ++ AC++E
Sbjct: 105 VRLPSK---HIWLPDVVLYNN-ADGMYEVSFYSNAVVSYDGSIFWLPPAIYKS-ACKIEV 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYM 179
+ +P D Q+C + S++Y ++ +++ ++ I P R E
Sbjct: 160 KHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNEN---- 215
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D Y + F R+ + I P L+ L+ F+L D
Sbjct: 216 -PDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSD 261
>UniRef50_A7RFJ5 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 328
Score = 42.7 bits (96), Expect = 0.017
Identities = 39/220 (17%), Positives = 90/220 (40%), Gaps = 7/220 (3%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
PV+V F + + +++ ++ +++Q W L F G + + + P D
Sbjct: 28 PVVVTFGAKLGRIAAVDEKNNVVLAHWYLKQKWVNPSLSWNASEFG-GVNTLHVEP---D 83
Query: 70 NLWHPDPYFLNSK--VTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
LW PD N+ ++A + + + + T+ + A AC M+ + +P D
Sbjct: 84 RLWVPDIVLYNNADPKNDLAGGFQYKTKIEMQADGTMIWLAPAMFHSACPMDIRYFPFDE 143
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYS 187
QSC + S+ Y K+ + + ++ I + L +++ Y
Sbjct: 144 QSCDLQFASWMYDTSKLEMKIDANETKVMDTFTNKEWEIPK-LTIKKKRIKYTCCPNPYE 202
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
+ + R+ ++++ P SL+ +++ +F L ++
Sbjct: 203 DVTITMSLVRRPYYYIMNMIFPCSLIACMTYLTFILPAES 242
>UniRef50_A2TM48 Cluster: Nicotinic acetylcholine receptor alpha 1
subunit; n=3; Aphidinae|Rep: Nicotinic acetylcholine
receptor alpha 1 subunit - Sitobion avenae (English
grain aphid)
Length = 496
Score = 42.7 bits (96), Expect = 0.017
Identities = 27/147 (18%), Positives = 67/147 (45%), Gaps = 6/147 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V+V+ + + + +N++D ++++ W++ + + E + G
Sbjct: 39 IRPVSNNTDTVLVKLGLRLSQLIELNLKDQILTTNVWLEHEWADHKF-IWEPLEYGGVKE 97
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E ++W PD N+ E T + L+ + V ++ +C+++
Sbjct: 98 LYVPSE---HIWLPDIVLYNNADGEYVVTT--MTKAVLHHSGKVMWTPPAIFKSSCEIDV 152
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFR 147
+ +P D Q+C + S+SY + +
Sbjct: 153 RYFPFDQQTCFMKFGSWSYDGNLINLK 179
>UniRef50_Q04844 Cluster: Acetylcholine receptor subunit epsilon
precursor; n=35; Euteleostomi|Rep: Acetylcholine
receptor subunit epsilon precursor - Homo sapiens
(Human)
Length = 493
Score = 42.7 bits (96), Expect = 0.017
Identities = 34/157 (21%), Positives = 70/157 (44%), Gaps = 8/157 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP V + + + ++ S+N ++ ++I W + RL +D F G + +
Sbjct: 40 RPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFG-GIETL 98
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+P E +W P+ L + + + + ++V +Y +V + C +E
Sbjct: 99 RVPSEL---VWLPE-IVLENNIDGQFGVAYD-ANVLVYEGGSVTWLPPAIYRSVCAVEVT 153
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWS--EAGVTIN 156
+P D Q+C + S +Y+ ++V F ++ G TIN
Sbjct: 154 YFPFDWQNCSLIFRSQTYNAEEVEFTFAVDNDGKTIN 190
>UniRef50_Q66T35 Cluster: Nicotinic acetylcholine receptor subunit
alpha 3; n=7; Coelomata|Rep: Nicotinic acetylcholine
receptor subunit alpha 3 - Anopheles gambiae (African
malaria mosquito)
Length = 710
Score = 42.3 bits (95), Expect = 0.023
Identities = 34/149 (22%), Positives = 71/149 (47%), Gaps = 10/149 (6%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V+ + + + +N+++ ++++ QTW + +L+ + G +
Sbjct: 39 VRPVVNVTDALTVKIKLKLSQLIDVNLKNQIMTTNLWVEQTWYDYKLKWEPKEYG-GVEM 97
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAII--ACQM 118
+ +P D++W PD N+ E+T + TL N T R R AI +C++
Sbjct: 98 LHVPS---DHIWRPDIVLYNNADGNF-EVTLA-TKATL--NYTGRVEWRPPAIYKSSCEI 150
Query: 119 EFQLYPMDIQSCPIYIESFSYSNQKVRFR 147
+ + +P D Q+C + S++Y +V R
Sbjct: 151 DVEYFPFDEQTCVMKFGSWTYDGFQVDLR 179
>UniRef50_A7RJP2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 140
Score = 42.3 bits (95), Expect = 0.023
Identities = 28/109 (25%), Positives = 50/109 (45%), Gaps = 7/109 (6%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP G+PV + I+ + I +M+ V +++R W + RL D +
Sbjct: 38 RPGVDTGKPVELGVDIHFDNFGRIEEMNMEVDVFLYMRYNWKDPRLA------NFTDKTI 91
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEI-AELTHKFSSVTLYRNQTVRYSAR 109
T + +W PD Y N++ +++ E T S + + RN ++ YS R
Sbjct: 92 TFTRGDIEKVWRPDTYCSNARESDLPLEETKTHSMLRIDRNGSIYYSRR 140
>UniRef50_UPI0000E49D12 Cluster: PREDICTED: similar to acetylcholin
receptor alpha subunit 1A; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to acetylcholin
receptor alpha subunit 1A - Strongylocentrotus
purpuratus
Length = 462
Score = 41.9 bits (94), Expect = 0.030
Identities = 45/229 (19%), Positives = 89/229 (38%), Gaps = 10/229 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q V + + ++ + N + ++ TW + LQ ++ G
Sbjct: 59 VRPVYNYRQTTYVYLRMLIYELVAFNEHSQHITLRSNMKMTWRDEYLQWDPSEWD-GITS 117
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
VTL P ++W PD + L V + + + Y TVR+ + AC++
Sbjct: 118 VTLRPS---DIWKPD-FDLEQNVERVHFIVADTYVIADYTG-TVRWIFPVITTTACKINI 172
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
+P D+Q C + ++ N ++R +E + ++ ++ + + N +
Sbjct: 173 VYFPYDVQQCNVTFYPWTLDNSQMRL-LAEDDDDAHQQM-YIRNGVWDLTNFQAANESIP 230
Query: 181 DK--DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
K + +V R+ Q PS + +L SFWL D+
Sbjct: 231 YKCCPHPFDHVVYTLDLAREAAFFTTQIVMPSVFLSILMLISFWLHPDS 279
>UniRef50_Q9XTY8 Cluster: Putative uncharacterized protein lgc-25;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein lgc-25 - Caenorhabditis elegans
Length = 502
Score = 41.9 bits (94), Expect = 0.030
Identities = 34/144 (23%), Positives = 55/144 (38%), Gaps = 5/144 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V + + V ++ + V I TW + +Q D +E
Sbjct: 42 VRPVKSEATVTQVNVFLSIAHVEKVDEHEQTALVHGHIWATWIDEYMQW--DAKKENVTK 99
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+T+ +LW P NS L T+Y V + + CQ +F
Sbjct: 100 LTISAH---SLWQPALALYNSARGNSWHLYMGAMPATVYSTGKVWSTGTFSFYVTCQFDF 156
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D QSCPI I + Y+ +V
Sbjct: 157 TNWPFDQQSCPIVIADWVYNLNQV 180
>UniRef50_Q29ND1 Cluster: GA17977-PA; n=3; Schizophora|Rep:
GA17977-PA - Drosophila pseudoobscura (Fruit fly)
Length = 531
Score = 41.9 bits (94), Expect = 0.030
Identities = 39/173 (22%), Positives = 75/173 (43%), Gaps = 12/173 (6%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A + +P+ V+F + + + ++ ++ ++++ W++ L+ E + G +
Sbjct: 27 RPVANESEPLEVKFGLTLQQIIDVDEKNQLLITNLWLSLEWNDYNLRWNETEY-GGVKDL 85
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+ P + LW PD NS H +++ + N + Y C+++
Sbjct: 86 RITP---NKLWKPDVLMYNSADEGFDGTYH--TNIVVKHNGSCLYVPPGIFKSTCKIDIT 140
Query: 122 LYPMDIQSCPIYIESFSY-SNQKVRFRWSEAGVTI-----NPELKLLQYHIGQ 168
+P D Q C + S++Y NQ SE G + N E LL YH G+
Sbjct: 141 WFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDGGDLSDFITNGEWYLLGYHAGK 193
>UniRef50_UPI0000E4930A Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor subunit Dalpha7; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor subunit Dalpha7 -
Strongylocentrotus purpuratus
Length = 1094
Score = 41.5 bits (93), Expect = 0.040
Identities = 56/279 (20%), Positives = 101/279 (36%), Gaps = 16/279 (5%)
Query: 30 MDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAEL 89
+ F ++RQ W++ L + + G D + + P D +W PD NS +
Sbjct: 749 LSFLTSSWMRQRWTDPTLAWNKSEYG-GLDKIRVLP---DMIWRPDILVYNSAAPKFDPT 804
Query: 90 THKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWS 149
H + VT+ + +C ++ +P DIQ C I S++Y V
Sbjct: 805 FH--TKVTVTSEGLCEWIPPGIFKTSCPIDVTYFPFDIQECEIKFGSWTYGGFTVDLELL 862
Query: 150 EAGVTINPELKLLQYH----IGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQ 205
V +N + ++ IG P ++ Y + Y L Y R+ ++ +
Sbjct: 863 SDEVAMNDTSEFVKNGEWNLIGMPAE-KKIKNYTCCPE-TYPSLHFYITIRRRALYYTLN 920
Query: 206 TFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKA-LDL 264
P ++ L+ F L +++ G F L A+ P V L
Sbjct: 921 ILVPCLVISSLALVGFTLPVES--GEKLSFGITILLSLTVFMLLVAEAMPATSVSVPLIA 978
Query: 265 WMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPR 303
C++ + A F V+ L+ Y+ + S R
Sbjct: 979 KYFDCVLMMVAVSVVFTVI-TLNIHYRHPNSHVMASWQR 1016
>UniRef50_Q4SGK0 Cluster: Chromosome 3 SCAF14593, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 3
SCAF14593, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 359
Score = 41.5 bits (93), Expect = 0.040
Identities = 24/92 (26%), Positives = 44/92 (47%), Gaps = 6/92 (6%)
Query: 47 LQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRY 106
L L D + D + LP +W P+ + N T+ + H + +Y N TV++
Sbjct: 104 LDLAWDTADYEYDEMVLPVA---KVWTPELHVTNGINTD---MKHSSQDLLVYSNGTVKH 157
Query: 107 SARMHAIIACQMEFQLYPMDIQSCPIYIESFS 138
S + A I C++ YP +CP+ I++++
Sbjct: 158 SVTLSAEINCEVNLFNYPFAFDACPVAIQAWT 189
>UniRef50_O62083 Cluster: Putative uncharacterized protein acr-19;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acr-19 - Caenorhabditis elegans
Length = 554
Score = 41.5 bits (93), Expect = 0.040
Identities = 32/139 (23%), Positives = 61/139 (43%), Gaps = 6/139 (4%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP + + V+V + + I+ + ++++R +W++ L F + V
Sbjct: 41 RPVRNESEAVVVLLGMDYQQILDIDEKHQIMNSNVWLRMSWTDHYLTWDPSEFGNIKE-V 99
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
LP +N+W PD NS V + + T ++V LY V + +C ++
Sbjct: 100 RLP---INNIWKPDVLLYNS-VDQQFDSTWPVNAVVLYTGN-VTWIPPAIIRSSCAIDIA 154
Query: 122 LYPMDIQSCPIYIESFSYS 140
+P D Q C + S++YS
Sbjct: 155 YFPFDTQHCTMKFGSWTYS 173
>UniRef50_P07510 Cluster: Acetylcholine receptor subunit gamma
precursor; n=31; Gnathostomata|Rep: Acetylcholine
receptor subunit gamma precursor - Homo sapiens (Human)
Length = 517
Score = 41.5 bits (93), Expect = 0.040
Identities = 37/157 (23%), Positives = 70/157 (44%), Gaps = 9/157 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP R V V + + ++ S+N + +++I W + RL+ P D EG
Sbjct: 41 LRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPRDY--EGLW 98
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P +W PD L + V + E+ + +V + + + + AC +
Sbjct: 99 VLRVPSTM---VWRPD-IVLENNVDGVFEVA-LYCNVLVSPDGCIYWLPPAIFRSACSIS 153
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWS-EAGVTI 155
+P D Q+C + +S +YS ++ + S E G TI
Sbjct: 154 VTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQEDGQTI 190
>UniRef50_P30532 Cluster: Neuronal acetylcholine receptor subunit
alpha-5 precursor; n=70; Euteleostomi|Rep: Neuronal
acetylcholine receptor subunit alpha-5 precursor - Homo
sapiens (Human)
Length = 468
Score = 41.5 bits (93), Expect = 0.040
Identities = 28/144 (19%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + ++F + + + ++ ++ +++++Q W + +L+ D + G
Sbjct: 62 VRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDY--GGIK 119
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V P D++W PD ++ + K +V Y N TV ++ + +C ++
Sbjct: 120 VIRVPS--DSVWTPDIVLFDNADGRFEGTSTK--TVIRY-NGTVTWTPPANYKSSCTIDV 174
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D+Q+C + S++Y +V
Sbjct: 175 TFFPFDLQNCSMKFGSWTYDGSQV 198
>UniRef50_Q23022 Cluster: Acetylcholine receptor subunit alpha-type
unc-38 precursor; n=9; Chromadorea|Rep: Acetylcholine
receptor subunit alpha-type unc-38 precursor -
Caenorhabditis elegans
Length = 511
Score = 41.5 bits (93), Expect = 0.040
Identities = 30/158 (18%), Positives = 67/158 (42%), Gaps = 6/158 (3%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP +P+ ++ + + + ++ D ++++QTW + +L D G +V
Sbjct: 43 RPSTSPNKPLTIKLKLRLSQIIDVHEIDQIMTCSVWLKQTWIDRKLSW--DPVNYGGVNV 100
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P ++ +W PD N+ + +T + TL+ V + CQ++ +
Sbjct: 101 LYVP--YEMIWVPDIVLYNNADSNY-NITIS-TKATLHYTGEVTWEPPAIFKSMCQIDVR 156
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPEL 159
+P D Q C + S+++S + +E + E+
Sbjct: 157 WFPFDEQQCHLKFGSWTFSENLLSVELNEPSLRYEEEI 194
>UniRef50_Q2IWF4 Cluster: Neurotransmitter-gated ion-channel
ligand-binding precursor; n=5; Rhodopseudomonas
palustris|Rep: Neurotransmitter-gated ion-channel
ligand-binding precursor - Rhodopseudomonas palustris
(strain HaA2)
Length = 353
Score = 41.1 bits (92), Expect = 0.053
Identities = 44/220 (20%), Positives = 88/220 (40%), Gaps = 13/220 (5%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDHVTLPPE-F 67
P+ V ++V+D+ + R+ + + Q W++ R + P ++ D V + F
Sbjct: 36 PMQVRVGLHVLDITEVKEVAGRARLHIEVTQRWTDPRRRFDPVEVGATRVDRVGAEADQF 95
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+W P N +I E + +++ Y + ++ R A ++ +P+D
Sbjct: 96 LAGIWTPGVAIDN----QIGEPRSRTQAISAYADGSIVMVERYEADFRVAIDMSAFPIDR 151
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRL----EETNGYMIDKD 183
Q + Y+ Q+ +E+ + L +PL L +E G+
Sbjct: 152 QKLTLSFSLPRYAKQEAMLVTTESDRQFSRIDNKLSVIDWRPLDLTFFYDEATGW---NA 208
Query: 184 GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+YSRL ER +L++ F P + +S F W+
Sbjct: 209 RSYSRLNSTVGIERLSERYLLRLFIPILSTLAVSLFVLWI 248
>UniRef50_Q9XTE5 Cluster: Putative uncharacterized protein lgc-31;
n=3; Caenorhabditis|Rep: Putative uncharacterized
protein lgc-31 - Caenorhabditis elegans
Length = 503
Score = 41.1 bits (92), Expect = 0.053
Identities = 38/200 (19%), Positives = 88/200 (44%), Gaps = 16/200 (8%)
Query: 25 INVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVT 84
I+ ++ D F++ W+ S + E+IF D PEF +L+ Y LN
Sbjct: 4 ISYSKNEYWEDEFLK--WNPSSYEGAEEIFLSSSD--IWIPEF--SLY----YSLN--FN 51
Query: 85 EIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKV 144
+ +L Y Q VRY + C+++ + +P D+Q C + S+++SN +
Sbjct: 52 DAVKLQSNNDVRVNYTGQ-VRYYIPFSSESLCKLDVKFFPFDVQQCSLLFGSWAHSNDSI 110
Query: 145 RFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM---IDKDGNYSRLVVYFRFERQIGH 201
++ +++ ++ + ++G++ +D + +++ +RQ +
Sbjct: 111 KYSLYSQNLSLIDFYDNQEWELDTHNSSVHSDGFLYDYLDPPLFWEMIIITLVMKRQSFY 170
Query: 202 HLIQTFAPSSLVVMLSWFSF 221
++ PS+++ ++S F
Sbjct: 171 YVFNLVIPSTMITLVSVIGF 190
>UniRef50_P54244 Cluster: Acetylcholine receptor subunit alpha-type
deg-3 precursor; n=2; Caenorhabditis|Rep: Acetylcholine
receptor subunit alpha-type deg-3 precursor -
Caenorhabditis elegans
Length = 564
Score = 41.1 bits (92), Expect = 0.053
Identities = 35/153 (22%), Positives = 70/153 (45%), Gaps = 12/153 (7%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V SI + + ++ + ++++++ Q W + L + E G +
Sbjct: 68 VRPILDHKKSLKVHISISLYQIIEVDEPSQNIKLNVWMIQKWRDEYLDWNPN--EYGMIN 125
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRN-----QTVRYSARMHAI-- 113
T+ P F +LW PD Y NS V + T ++ ++ N + S AI
Sbjct: 126 STIIP--FHHLWIPDTYLYNS-VKMSRDETERYMNIQATSNYWKGEKGAELSFLYPAIYT 182
Query: 114 IACQMEFQLYPMDIQSCPIYIESFSYSNQKVRF 146
I C++ + +P D Q+C + I S++ S + +
Sbjct: 183 ITCRLNIRFFPYDRQNCTLTISSWTNSKSALDY 215
>UniRef50_Q7T2R4 Cluster: Nicotinic acetylcholine receptor alpha 9d
subunit; n=7; Clupeocephala|Rep: Nicotinic acetylcholine
receptor alpha 9d subunit - Fugu rubripes (Japanese
pufferfish) (Takifugu rubripes)
Length = 521
Score = 40.7 bits (91), Expect = 0.070
Identities = 50/278 (17%), Positives = 107/278 (38%), Gaps = 12/278 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V I + + ++ + +++RQ W ++ L ++ ++ G D
Sbjct: 24 LRPVEDTDHIINVTLQITLSQIIDMDERNQILTTYLWVRQVWMDAYLTWKKEDYD-GLDT 82
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P + +W PD NS E + ++V L + V + +C ++
Sbjct: 83 IRIPSSY---VWRPDIVLYNSADDEFSSSME--TNVVLRHDGQVMWDQPAITKSSCSVDV 137
Query: 121 QLYPMDIQSCPIYIESFSYS-NQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+P D+Q C + S++++ NQ F ++ + + +G P + + Y
Sbjct: 138 AHFPFDLQECHLTFGSWTHNGNQMDLFNALDSADLADFVPNVEWEVLGMPAK-KNVILYG 196
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXX 239
D Y + +R+ ++ P ++ L+ F+L D+ G
Sbjct: 197 CCSD-PYPDITFTLHLKRRASFYIFNLLIPCMMISFLAPLGFYLPADS--GEKVSLGVTV 253
Query: 240 XXXXXXFTGLRAD-IPPVAYVKALDLWMAGCMMFVFAA 276
F L A+ +PP V + + M V A+
Sbjct: 254 LLALTVFQLLVAESMPPSESVPLIGKYYIATMTMVTAS 291
>UniRef50_Q6F6K3 Cluster: Acetylcholine receptor protein 17, isoform
b; n=4; Caenorhabditis|Rep: Acetylcholine receptor
protein 17, isoform b - Caenorhabditis elegans
Length = 515
Score = 40.7 bits (91), Expect = 0.070
Identities = 43/226 (19%), Positives = 82/226 (36%), Gaps = 19/226 (8%)
Query: 10 PVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDHVTLPPEFF 68
P V +Y + ++ D + +I + W + L P D HV P E
Sbjct: 49 PTNVTVQLYFKQIQKVHENDQIITLYCWIEEYWQDEFLTWNPSDFGNIKSLHV--PSEM- 105
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD N+ I E ++V + + + I C ++ + +P D Q
Sbjct: 106 --IWKPDLLVYNNANMNIKE-NEMQTNVQIEHTGKISLFRAIITDITCDLQMEKFPYDQQ 162
Query: 129 SCPIYIESFSYSNQKVRFRWSE------AGVTINPELKLLQYHIGQ------PLRLEETN 176
C I + S+SY ++ +E + L +L ++I R
Sbjct: 163 ICFIMLASWSYDGSQIMLNTAEQPTEAPLDIKNTTNLAILNHYIPNMEWKLVDFRYRNNL 222
Query: 177 GYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFW 222
Y Y + +F +R ++L PS+ + +++ F+
Sbjct: 223 KYYDCCPNPYPDISYFFAIKRNPSYYLFTLIIPSAFITIVTVIGFF 268
>UniRef50_Q2XWK4 Cluster: Nicotinic acetylcholine receptor subunit
type I; n=1; Lymnaea stagnalis|Rep: Nicotinic
acetylcholine receptor subunit type I - Lymnaea
stagnalis (Great pond snail)
Length = 527
Score = 40.7 bits (91), Expect = 0.070
Identities = 34/223 (15%), Positives = 89/223 (39%), Gaps = 8/223 (3%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP + V F + ++ + ++ + + M+ R W++ L+ + + +
Sbjct: 78 RPVINTSDNMTVLFGLSLIQILDVDESNQVLKASMWYRYEWNDMLLKW-DPAMHDDIQSI 136
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+P +W PD N + E + + + N +++ + +C + +
Sbjct: 137 RIPSSM---IWLPDILLYNFADDRLRE--QRDALCIVQNNGDIQWMPQAILRSSCSFDTK 191
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
+P D+QSC + S++Y+ K+ + E ++ + ++ I + + Y
Sbjct: 192 YFPFDVQSCWLKFGSWTYNGFKLNVEFVREHSFDLSDYVMSNEWDIIENRAVRNVKYYTC 251
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ + L + +R+ + P +L+ +L+ FW+
Sbjct: 252 CPE-PFPDLTFHLTLKRKTAFYTFILILPCTLLSLLTLVIFWV 293
>UniRef50_A7S9T6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 321
Score = 40.7 bits (91), Expect = 0.070
Identities = 54/283 (19%), Positives = 114/283 (40%), Gaps = 19/283 (6%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP R + V V F I + ++ ++ ++++R W + L E F G
Sbjct: 19 VRPVKRVEEVVPVSFDIGYSQMVNLVEKNQILISNLWVRLKWYDPWLTWNESDFG-GMKS 77
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSS-VTLYRNQTVRYSARMHAIIACQME 119
+ + P +W PD N+ ++ + +KF++ V ++ + TV++ + + C+++
Sbjct: 78 IKVDPSC---VWVPDIVLYNNVDSDSSGEMYKFTTKVNIHSDGTVQWLSPIQVKSECKID 134
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGV-----TINPELKLLQYHIGQPLRLEE 174
+P+D Q C + S++Y ++ + T N E ++L + + L
Sbjct: 135 ITNFPLDEQFCKLEFGSWAYDGFELNLTNARETADLSLYTTNGEWRMLSGKVTRKL---- 190
Query: 175 TNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXX 234
+ Y L+ F +R+ +++ P L+ LS +F ++ G
Sbjct: 191 --SKFPCCEAPYITLIYMFHVQRRALFYVMNLIIPCVLLTFLSALTFRFPPES--GERVS 246
Query: 235 XXXXXXXXXXXFTGLRAD-IPPVAYVKALDLWMAGCMMFVFAA 276
F + D IPP + V L C +F+ +
Sbjct: 247 LTITILLGMTVFMLIFIDNIPPTSEVMPLIGKYFSCSLFIMGS 289
>UniRef50_UPI00015B4A35 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor alpha9 subunit; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to nicotinic
acetylcholine receptor alpha9 subunit - Nasonia
vitripennis
Length = 431
Score = 40.3 bits (90), Expect = 0.092
Identities = 34/181 (18%), Positives = 75/181 (41%), Gaps = 10/181 (5%)
Query: 54 FEEGDDHVTLPPEFFDN----------LWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQT 103
FE D H+T PE FD +W PD NS E ++ + L +
Sbjct: 85 FEWTDQHLTWKPEDFDGVQETRVKSDEIWVPDFALYNSGDMETSQTGIPETLCQLSHTGS 144
Query: 104 VRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQ 163
V + C+ +F +P D Q+C + + S++++ +++ F + + + ++ + +
Sbjct: 145 VICLPSIKYKTLCESDFTYWPYDKQTCTLRMGSWTHTGEEISFDFKNSSIDMSNYRENNE 204
Query: 164 YHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ I ++ Y + + L++ F R P+ ++++++ WL
Sbjct: 205 WKILNYTASKKNPKYSCCPNETFPSLLLDFELARHPTMLHAAYITPAVVLMVITLTVLWL 264
Query: 224 D 224
D
Sbjct: 265 D 265
>UniRef50_UPI000041A8E7 Cluster: PREDICTED: similar to
Gamma-aminobutyric-acid receptor alpha-5 subunit
precursor (GABA(A) receptor); n=1; Homo sapiens|Rep:
PREDICTED: similar to Gamma-aminobutyric-acid receptor
alpha-5 subunit precursor (GABA(A) receptor) - Homo
sapiens
Length = 207
Score = 40.3 bits (90), Expect = 0.092
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Query: 116 CQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAG----VTINPELKLLQYHI-GQPL 170
C M+ + +PMD +CP+ S++Y N +V + W+ V +L QYH+ GQ +
Sbjct: 51 CPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTV 110
Query: 171 RLE 173
E
Sbjct: 111 GTE 113
>UniRef50_A7T7Z5 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 152
Score = 39.9 bits (89), Expect = 0.12
Identities = 29/132 (21%), Positives = 58/132 (43%), Gaps = 7/132 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP + + V F++ +V + ++ + RV+++ Q W + L P D G +
Sbjct: 21 VRPVMNNHEQLKVYFALKLVQIVDVDGKSEAVRVNVWTTQNWKDPFLTWDPSDY--GGIE 78
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSS-VTLYRNQTVRYSARMHAIIACQM 118
+ + P +W P N+ A K+ + V + N TV + A + +C++
Sbjct: 79 EINVTPTM---VWLPIIILYNNAANGFAGGPEKYKTKVVINSNGTVNWFAATQFLFSCKI 135
Query: 119 EFQLYPMDIQSC 130
+ +P D Q C
Sbjct: 136 NIRWFPFDEQYC 147
>UniRef50_P91766 Cluster: Acetylcholine receptor subunit alpha-like
precursor; n=31; Coelomata|Rep: Acetylcholine receptor
subunit alpha-like precursor - Manduca sexta (Tobacco
hawkmoth) (Tobacco hornworm)
Length = 516
Score = 39.9 bits (89), Expect = 0.12
Identities = 33/149 (22%), Positives = 69/149 (46%), Gaps = 10/149 (6%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V + + + +N+++ ++++ Q+W + +L + G +
Sbjct: 40 VRPVLNVSDALTVRIKLKLSQLIDVNLKNQIMTTNLWVEQSWYDYKLSWEPREYG-GVEM 98
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAII--ACQM 118
+ +P D++W PD N+ E+T + TL N T R R AI +C++
Sbjct: 99 LHVPS---DHIWRPDIVLYNNADGNF-EVTLA-TKATL--NYTGRVEWRPPAIYKSSCEI 151
Query: 119 EFQLYPMDIQSCPIYIESFSYSNQKVRFR 147
+ + +P D Q+C + S++Y +V R
Sbjct: 152 DVEYFPFDQQTCVMKFGSWTYDGFQVDLR 180
>UniRef50_UPI0000E47C59 Cluster: PREDICTED: similar to alpha-9
nicotinic acetylcholine receptor subunit precursor; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
alpha-9 nicotinic acetylcholine receptor subunit
precursor - Strongylocentrotus purpuratus
Length = 451
Score = 39.5 bits (88), Expect = 0.16
Identities = 40/214 (18%), Positives = 79/214 (36%), Gaps = 5/214 (2%)
Query: 71 LWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSC 130
+W PD N+ E + K V + V ++A C + +P D Q C
Sbjct: 68 VWMPDVVLYNNAAKEYKDFM-KDEIVVITNEGQVNWAAPKIISSYCSINVNTFPFDEQQC 126
Query: 131 PIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLV 190
P+ + + +++R W + Q+ I Y Y+ +
Sbjct: 127 PMKFGPWQHEGKELRI-WGGGSGDASVFNSDGQWDILAMTAKSNEVEYPDAPGKTYTDVT 185
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
+F+R+ +++ P + V M++ SF+L ++ G F L
Sbjct: 186 YVIKFKRRPLYYVFNLILPCTFVSMVALLSFFLPPES--GEKISLGITVLLSLTVFLLLV 243
Query: 251 AD-IPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
A+ +PP + V + + M+ + +L V+V
Sbjct: 244 AETMPPTSAVPVVGQYFMSTMVLISGSLAMSVMV 277
>UniRef50_UPI0000ECB6ED Cluster: Acetylcholine receptor subunit
alpha precursor.; n=1; Gallus gallus|Rep: Acetylcholine
receptor subunit alpha precursor. - Gallus gallus
Length = 352
Score = 39.5 bits (88), Expect = 0.16
Identities = 26/144 (18%), Positives = 65/144 (45%), Gaps = 6/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP V+V + ++ + +++ + ++ ++Q W++ L+ D + G
Sbjct: 38 VRPVENHRDAVVVTVGLQLIQLINVDEVNQIVTTNVRLKQQWTDINLKWNPDDYG-GVKQ 96
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D++W PD N+ + A + K++ V L + ++ C++
Sbjct: 97 IRIPS---DDIWRPDLVLYNNADGDFAIV--KYTKVLLEHTGKITWTPPAIFKSYCEIIV 151
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + + +++Y V
Sbjct: 152 TYFPFDQQNCSMKLGTWTYDGTMV 175
>UniRef50_Q6TMY0 Cluster: Nicotinic acetylcholine receptor non-alpha
subunit precursor; n=3; Schistosoma|Rep: Nicotinic
acetylcholine receptor non-alpha subunit precursor -
Schistosoma bovis (Blood fluke)
Length = 740
Score = 39.5 bits (88), Expect = 0.16
Identities = 31/146 (21%), Positives = 64/146 (43%), Gaps = 12/146 (8%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP + G+PV V ++ + ++ ++ +++ WS+ +E +
Sbjct: 52 RPVSVDGKPVQVFLKCFLNQIMDVDEKNQVLSTIIWLDLKWSDYHFHWNASDYEN-IRQI 110
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQ-TVRY--SARMHAIIACQM 118
LPPE +W PD NS + ++ F + + RN +++ H+I C +
Sbjct: 111 NLPPE---RIWKPDILLYNSASEKFDQI---FPTKVIVRNTGNIQWVPPGLFHSI--CDI 162
Query: 119 EFQLYPMDIQSCPIYIESFSYSNQKV 144
E +P D Q+C + + +++Y V
Sbjct: 163 EVNWFPFDSQNCIMKLGTWTYQGNTV 188
>UniRef50_A7RFJ2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 278
Score = 39.5 bits (88), Expect = 0.16
Identities = 41/229 (17%), Positives = 95/229 (41%), Gaps = 14/229 (6%)
Query: 3 PPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVT 62
P + +P+ V FS +++ + +N ++ + ++I++ W L + F G+
Sbjct: 23 PLRNRSEPITVVFSAHLLGLAKVNEKEQSIKTHLWIKEEWYNPFLMWNPEEF--GNITEI 80
Query: 63 LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQL 122
+ P + +W PD N T L + + N T R A + + C ++ +
Sbjct: 81 IVPA--NMIWVPDIILYNKGST----LFNTKVIIAFNGNNTWRSPAIYNTM--CVLDVKY 132
Query: 123 YPMDIQSCPIYIESFSYSNQKVRF-RWSEAGVTINPELKLLQYHIGQPLRLEETNGYMID 181
+P D Q+C + S++ K+ S+ + KL Q + + + Y +
Sbjct: 133 FPFDEQTCDLVFASWTRDISKLNLVTTSDTVPRSRRDSKLFQENEEWRVMFAKMKRYEVI 192
Query: 182 KDGN---YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
D + + + + R +R+ ++++ P +L+ + F L ++
Sbjct: 193 FDWSEIPVADVTISVRLQRRTYYYVMNLILPCTLIACTIFLEFILPAES 241
>UniRef50_UPI0000D55E50 Cluster: PREDICTED: similar to AcetylCholine
Receptor family member (acr-21); n=3; Endopterygota|Rep:
PREDICTED: similar to AcetylCholine Receptor family
member (acr-21) - Tribolium castaneum
Length = 649
Score = 39.1 bits (87), Expect = 0.21
Identities = 30/157 (19%), Positives = 65/157 (41%), Gaps = 6/157 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP P+ V F I + + ++ ++ + +I Q W + L+ F G
Sbjct: 35 VRPVENSSLPLTVIFGISLHHIIDVDEKNQILTTNCWITQAWIDHHLRWNASDFA-GIKV 93
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P + +W PD N+ + + + + + S ++ +C +
Sbjct: 94 IRIP---YTRVWRPDLILYNNADPQFQSSVINTNVIVSSSGEVLWLSHGIYRS-SCDINV 149
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRF-RWSEAGVTIN 156
+ +P D+QSC + S++Y +V + +E G N
Sbjct: 150 EYFPFDLQSCHMKWASWTYDGYQVELAKQTEEGDVSN 186
>UniRef50_Q5BZP4 Cluster: SJCHGC07923 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC07923 protein - Schistosoma
japonicum (Blood fluke)
Length = 247
Score = 39.1 bits (87), Expect = 0.21
Identities = 19/50 (38%), Positives = 29/50 (58%), Gaps = 1/50 (2%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPE 51
RPP G IV ++ V+ + SI+V MD+ +D+ +RQ W + RL E
Sbjct: 162 RPPDG-GNATIVTVNMKVLAIFSIDVRTMDYYIDLLLRQVWRDRRLSWQE 210
>UniRef50_Q22224 Cluster: Putative uncharacterized protein acr-14;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein acr-14 - Caenorhabditis elegans
Length = 500
Score = 39.1 bits (87), Expect = 0.21
Identities = 30/144 (20%), Positives = 62/144 (43%), Gaps = 3/144 (2%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEE-GDDH 60
RP P+ V+ + + ++ ++ + ++ W++ +L +F D
Sbjct: 37 RPVENSSAPLDVKVRFLLNQIMDVDEKNQVMSILAYMDYHWNDYKLTWDPKLFGGIRDVR 96
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ + LW PD NS V+E + T+ S + N V+ + CQ++
Sbjct: 97 FSGDDDASFKLWRPDVLLFNS-VSESFDSTYS-SRFIVSSNGDVQQNPPGIFRFVCQIDV 154
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
YP D Q+C + + S++Y+ Q +
Sbjct: 155 TYYPFDKQTCFLKLGSWTYNGQYI 178
>UniRef50_UPI0000E45D33 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor subunit alpha 6; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor subunit alpha 6 -
Strongylocentrotus purpuratus
Length = 440
Score = 38.7 bits (86), Expect = 0.28
Identities = 55/287 (19%), Positives = 100/287 (34%), Gaps = 8/287 (2%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP QPV V F + + ++ +++ V +R W++ LQ D G +
Sbjct: 51 VRPVKDHLQPVEVFFRMLLFELITLDETHQMVTVRSNMRLQWTDEYLQWDPDE-NGGIYN 109
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+TL + +W PD + + + V + + + AC+M
Sbjct: 110 ITLKT---NQVWRPDVVLDEDLDRDFISIPEADTFVIVQYTGAMDWLFPAITTSACKMNI 166
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
Q +P D Q C + ++ K+RF + + E + I
Sbjct: 167 QYFPFDTQQCVLTFYPWTLDESKMRFFAKNDEDALQARYVRNGIWSMTDFKPENFSFRYI 226
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
+ F+R+ G L P+ + L FWL D+ G
Sbjct: 227 CCPYPNDHIRYTLTFDREYGFFLSNIIVPAIFLTSLMLVGFWLHPDS--GEKVAFTVTNL 284
Query: 241 XXXXXFTGLRAD-IPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
F L +D +PP+ +++ + M+ V + F V VL
Sbjct: 285 LALILFQQLVSDSMPPIGEPRSI-IVTCFFMLVVVSGCSVFFSVLVL 330
>UniRef50_Q4SRT3 Cluster: Chromosome undetermined SCAF14492, whole
genome shotgun sequence; n=3; Clupeocephala|Rep:
Chromosome undetermined SCAF14492, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 457
Score = 38.7 bits (86), Expect = 0.28
Identities = 39/200 (19%), Positives = 84/200 (42%), Gaps = 11/200 (5%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V + V + +++ ++ ++ RQ+W++ L + F+E V++P N+W
Sbjct: 28 VAIDLMVYSILNVDEKNQVLTTYVWYRQSWTDEFLVWNPEDFDEVKQ-VSMPTA---NVW 83
Query: 73 HPDPYF--LNSKVTEIAEL--THKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
PD L S VT ++ + V + + VR + + AC + +P D+Q
Sbjct: 84 VPDILINELLSPVTCSVDVGKSPDIPYVYVSHDGLVRNYKPIQVVTACTLNIYNFPFDVQ 143
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNGYMIDKDGNY 186
C + +S+ ++ + + + + + L L + + +D D Y
Sbjct: 144 KCSLTFQSWLHTIDDINITLLRSPEELREDKSVFMNQGEWELLHILSKYKSFSVDNDDYY 203
Query: 187 SRLVVYFRFERQIGHHLIQT 206
+ + + RF R + LI+T
Sbjct: 204 AEMKFHVRF-RPVPGALIKT 222
>UniRef50_A7UFK6 Cluster: Nicotinic acetylcholine receptor alpha
subunit; n=2; Ascaris suum|Rep: Nicotinic acetylcholine
receptor alpha subunit - Ascaris suum (Pig roundworm)
(Ascaris lumbricoides)
Length = 513
Score = 38.7 bits (86), Expect = 0.28
Identities = 29/139 (20%), Positives = 60/139 (43%), Gaps = 6/139 (4%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP +PV ++ + + + ++ D ++++Q W + +L D G V
Sbjct: 41 RPAMSPHEPVTIKLKLRLSQIIDVHEIDQIMTYSVWLKQVWIDKKLSW--DPKNYGGVSV 98
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P ++ +W PD N+ + +T + TL+ + V + CQ++ +
Sbjct: 99 LYVP--YEMIWVPDIVLYNNADSNY-NITIS-TKATLHYSGEVTWEPPAIFKSMCQIDVR 154
Query: 122 LYPMDIQSCPIYIESFSYS 140
+P D Q C + S++YS
Sbjct: 155 WFPFDEQKCHLKFGSWTYS 173
>UniRef50_Q8JFN7 Cluster: Neuronal acetylcholine receptor subunit
alpha-9-I precursor; n=8; Clupeocephala|Rep: Neuronal
acetylcholine receptor subunit alpha-9-I precursor -
Oncorhynchus mykiss (Rainbow trout) (Salmo gairdneri)
Length = 572
Score = 38.7 bits (86), Expect = 0.28
Identities = 28/144 (19%), Positives = 63/144 (43%), Gaps = 6/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V I + + ++ + ++IRQTW ++ L+ ++ ++ G +
Sbjct: 40 LRPVEDTDKTLNVTLQITLSQIKDMDERNQVLTTYLWIRQTWFDAYLKWDKEEYD-GLEV 98
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P +W PD N E + ++V L N + + +C ++
Sbjct: 99 IRIPSNL---VWRPDIVLYNKADEEASGPAD--TNVVLRYNGEITWDMPAITKSSCVVDV 153
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q C + S++Y+ +V
Sbjct: 154 SYFPFDWQWCNLTFGSWTYNGNQV 177
>UniRef50_P25162 Cluster: Acetylcholine receptor subunit beta-like 2
precursor; n=7; Diptera|Rep: Acetylcholine receptor
subunit beta-like 2 precursor - Drosophila melanogaster
(Fruit fly)
Length = 519
Score = 38.7 bits (86), Expect = 0.28
Identities = 28/149 (18%), Positives = 70/149 (46%), Gaps = 16/149 (10%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V + + + +N+++ +++++Q W + +L+ + + G +
Sbjct: 45 IRPVVNNTETLTVWLGLKLSQLIEVNLKNQVMTTNLWVKQRWFDYKLRWDPEEYG-GVEQ 103
Query: 61 VTLPPEFFDNLWHPDPYFLNS-----KVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIA 115
+ +P E ++W PD N+ +VT + + T K++ + + S+
Sbjct: 104 LYVPSE---HIWVPDIVLYNNWDGNYEVTLMTKATLKYTGEVFWEPPAIYKSS------- 153
Query: 116 CQMEFQLYPMDIQSCPIYIESFSYSNQKV 144
C+M + +P D Q C + S++Y+ +V
Sbjct: 154 CEMNVEYFPYDEQICFMKFGSWTYNGAQV 182
>UniRef50_UPI00006602DC Cluster: Homolog of Homo sapiens
"5-hydroxytryptamine 3 receptor B subunit; n=1; Takifugu
rubripes|Rep: Homolog of Homo sapiens
"5-hydroxytryptamine 3 receptor B subunit - Takifugu
rubripes
Length = 271
Score = 38.3 bits (85), Expect = 0.37
Identities = 29/114 (25%), Positives = 47/114 (41%), Gaps = 6/114 (5%)
Query: 34 VDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKF 93
V +F Q W L +F + L P LW PD + V++ + +
Sbjct: 47 VPIFFPQKWKNEFLAWNSSVF----CGMELLPVSLSLLWVPD-IVIREDVSDTSS-NYMS 100
Query: 94 SSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFR 147
TL N V S R C+++ +L+P D+Q C + S S+S+ + R
Sbjct: 101 PLATLSSNGWVHSSLRHVLTSTCKLDLKLFPFDMQICNLSFGSMSFSDDIISMR 154
>UniRef50_Q4RRI3 Cluster: Chromosome 16 SCAF15002, whole genome
shotgun sequence; n=3; Euteleostomi|Rep: Chromosome 16
SCAF15002, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 636
Score = 38.3 bits (85), Expect = 0.37
Identities = 32/193 (16%), Positives = 83/193 (43%), Gaps = 9/193 (4%)
Query: 36 MFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSS 95
++IR+ W ++ L+ +D ++ G D + +P + +W PD N+ ++
Sbjct: 60 LWIRRVWVDAHLKWNKDEYD-GLDTIRIPSSY---VWRPDIVLYNNADDHFTGPMD--TN 113
Query: 96 VTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTI 155
V + + + + + +C+++ +P D Q C S++Y+ ++ + +
Sbjct: 114 VVIRHDGQITWDSPAITKSSCRVDVSFFPFDAQQCRFTYGSWTYNGNQLDILNALDSADL 173
Query: 156 NPELKLLQYHI-GQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVV 214
++ +++ I G P + + Y D Y + + +R+ ++ P ++
Sbjct: 174 ADLVENVEWEILGMPAK-KNVIQYGCCAD-PYPDVTYTLKLKRRASFYVFNLLIPCVMIS 231
Query: 215 MLSWFSFWLDLDA 227
L+ F+L D+
Sbjct: 232 FLAPLGFYLPADS 244
>UniRef50_P17644 Cluster: Acetylcholine receptor subunit alpha-like
2 precursor; n=38; Neoptera|Rep: Acetylcholine receptor
subunit alpha-like 2 precursor - Drosophila melanogaster
(Fruit fly)
Length = 576
Score = 38.3 bits (85), Expect = 0.37
Identities = 25/144 (17%), Positives = 64/144 (44%), Gaps = 6/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V+V+ + + + +N++D ++++ W + + + + G
Sbjct: 60 IRPVSNNTDTVLVKLGLRLSQLIDLNLKDQILTTNVWLEHEWQDHKFKWDPSEYG-GVTE 118
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E ++W PD N+ E T + L+ V ++ +C+++
Sbjct: 119 LYVPSE---HIWLPDIVLYNNADGEYVVTT--MTKAILHYTGKVVWTPPAIFKSSCEIDV 173
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+ +P D Q+C + S++Y ++
Sbjct: 174 RYFPFDQQTCFMKFGSWTYDGDQI 197
>UniRef50_UPI0000E4906A Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor subunit type G; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor subunit type G -
Strongylocentrotus purpuratus
Length = 705
Score = 37.9 bits (84), Expect = 0.49
Identities = 48/257 (18%), Positives = 91/257 (35%), Gaps = 10/257 (3%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP +PV V F + + + ++R +W + + D ++ G + +
Sbjct: 10 RPVRDAARPVWVYFRFLPSQIIKFDETQQQLTIMAYMRMSWRDEFITWNPDDYD-GIELL 68
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
L P +LW PD S E ++++ + V N T + C+++ +
Sbjct: 69 ALRPS---DLWLPDIALYQSCSKEF--ISYQETYVLCLYNGTCDWHFPAILTSTCKVDVR 123
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQ-YHIGQPLRLEETNGYMI 180
+P DIQ C + ++S V E + ++ + + +
Sbjct: 124 YFPFDIQLCDLTFGAWSADVTMVELHTFEVPDDTSDDIFAKNGVWTLESFTAINLRPFYV 183
Query: 181 DKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
N++ + R R+ PS L+ ML +FW D+ G
Sbjct: 184 CCPHNFTEIKYTLRLRRESAFFTKVVVVPSVLLTMLMALTFWSHPDS--GEKVTLAISNL 241
Query: 241 XXXXXFTGLRAD-IPPV 256
F L AD +PP+
Sbjct: 242 LAMILFQQLVADSMPPI 258
>UniRef50_UPI00006A0062 Cluster: UPI00006A0062 related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A0062 UniRef100 entry -
Xenopus tropicalis
Length = 457
Score = 37.9 bits (84), Expect = 0.49
Identities = 37/208 (17%), Positives = 80/208 (38%), Gaps = 4/208 (1%)
Query: 71 LWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSC 130
+W PD Y ++ + + + K + + +Y N V S + +C M+ +P D Q+C
Sbjct: 109 VWRPDLYIY--EMVDDDDKSPKINYLKIYYNGIVTNSKPLRIAGSCSMQNFKFPFDEQNC 166
Query: 131 PIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLV 190
+ S+ Y++ +V + + K + G + L GN++R+
Sbjct: 167 SLTFGSYVYNDFEVYMMAASNSSQVTENSKDIFRTKGDWILLNIIVRNNPLPSGNFNRVT 226
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
+R ++ P+ +V+L S + ++ GR L
Sbjct: 227 YEIHIKRNPIIYVFNLILPACFLVILDIASMF--MEGTEGRLTFKVTIVLGFSVLLLILS 284
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALG 278
+P L ++ + CM+ + ++G
Sbjct: 285 GMLPNSDTPPMLGIFFSVCMIMMVLSIG 312
>UniRef50_UPI00006603C6 Cluster: Homolog of Homo sapiens
"5-hydroxytryptamine (Serotonin) receptor 3A; n=1;
Takifugu rubripes|Rep: Homolog of Homo sapiens
"5-hydroxytryptamine (Serotonin) receptor 3A - Takifugu
rubripes
Length = 471
Score = 37.9 bits (84), Expect = 0.49
Identities = 39/155 (25%), Positives = 66/155 (42%), Gaps = 19/155 (12%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH- 60
RP QP IVE I + + S+ + +D QT + L D+ + ++H
Sbjct: 44 RPVLDHTQPTIVELDIILFAILSVPLTVRVLPLDTGDSQTCT-----LGFDVLQRWNNHR 98
Query: 61 VTLPPEFF----------DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARM 110
++ PE F D LW PD F+ + + + + VT + V +
Sbjct: 99 ISWDPEEFCGITKVSVPQDILWKPD-LFIYEMIQKDESPMNPYVEVTY--DGLVTSDQDV 155
Query: 111 HAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVR 145
+ C+M+ +P D QSC I I S +Y +++R
Sbjct: 156 KVVSTCKMDVHKFPFDTQSCNITIGSANYCAKEMR 190
>UniRef50_Q4S3I4 Cluster: Chromosome 1 SCAF14749, whole genome
shotgun sequence; n=2; Euteleostomi|Rep: Chromosome 1
SCAF14749, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 503
Score = 37.9 bits (84), Expect = 0.49
Identities = 30/144 (20%), Positives = 61/144 (42%), Gaps = 6/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V F + + + ++ ++ ++++ Q W + +L+ D + G
Sbjct: 27 VRPIQHANDTIKVRFGLKISQLVDVDEKNQLMTTNVWLCQEWIDYKLRWNPDKYG-GITS 85
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E NLW PD L E + ++ Y N + ++ AC M+
Sbjct: 86 IRVPSE---NLWLPD-IVLYENADGRFEGSLMTKAIVRY-NGAITWTPPASYKSACTMDV 140
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y V
Sbjct: 141 TFFPFDRQNCTMKFGSWTYDGTMV 164
>UniRef50_UPI0000E49844 Cluster: PREDICTED: similar to nicotinic
acetylcholine receptor alpha2 subunit; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
nicotinic acetylcholine receptor alpha2 subunit -
Strongylocentrotus purpuratus
Length = 570
Score = 37.5 bits (83), Expect = 0.65
Identities = 42/228 (18%), Positives = 94/228 (41%), Gaps = 9/228 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V F + + + ++ ++ +++++Q W + +LQ + D+
Sbjct: 94 IRPVENNSEVLDVNFRLTMSQLIDVDEKNQIMTTNVWLKQLWMDYKLQWNPAEY----DN 149
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+++ +W PD N+ E+T + +Y + TV + +C++
Sbjct: 150 ISILRVPSKMIWTPDLVLYNNADGNY-EVT-LMAKALVYSDGTVYWLPPAIYKSSCKINV 207
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYH-IGQPLRLEETNGYM 179
+ +P D Q CP+ S++Y + S V + + ++ IG P + T Y
Sbjct: 208 RYFPFDEQFCPMKFGSWTYDGSLIDLIPSSNDVDLEDYWQSGEWDIIGTPAN-KNTLKYP 266
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
D Y+ + R+ + + P L+ L+ F+L D+
Sbjct: 267 C-CDEIYTDITFTLHIRRKPLFYTVNLILPCVLISFLTVLVFYLPSDS 313
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.325 0.139 0.435
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 429,322,965
Number of Sequences: 1657284
Number of extensions: 16370037
Number of successful extensions: 44066
Number of sequences better than 10.0: 296
Number of HSP's better than 10.0 without gapping: 138
Number of HSP's successfully gapped in prelim test: 158
Number of HSP's that attempted gapping in prelim test: 43436
Number of HSP's gapped (non-prelim): 435
length of query: 418
length of database: 575,637,011
effective HSP length: 103
effective length of query: 315
effective length of database: 404,936,759
effective search space: 127555079085
effective search space used: 127555079085
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 74 (33.9 bits)
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