Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000843-TA|BGIBMGA000843-PA|IPR006202|Neurotransmitter-
gated ion-channel ligand-binding, IPR006028|Gamma-aminobutyric acid A
receptor, IPR006201|Neurotransmitter-gated ion-channel,
IPR006029|Neurotransmitter-gated ion-channel transmembrane region
(418 letters)
Database: human
224,733 sequences; 73,234,838 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine recept... 208 4e-53
X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine recept... 208 4e-53
U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3 ... 208 4e-53
U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2 ... 208 4e-53
BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein. 208 4e-53
BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha... 208 4e-53
BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha... 208 4e-53
BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha... 208 4e-53
AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2... 208 4e-53
AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha ... 208 4e-53
AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha ... 208 4e-53
Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4... 207 5e-53
U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B... 207 5e-53
CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein. 207 5e-53
AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2... 207 5e-53
AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha... 207 5e-53
BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein. 195 2e-49
U33267-1|AAB37750.1| 497|Homo sapiens glycine receptor beta sub... 193 8e-49
BC032635-1|AAH32635.1| 497|Homo sapiens glycine receptor, beta ... 193 8e-49
AF094755-1|AAC71034.1| 497|Homo sapiens glycine receptor beta s... 193 8e-49
AF094754-1|AAC71033.1| 497|Homo sapiens glycine receptor beta s... 193 8e-49
U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subuni... 177 8e-44
BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid... 177 8e-44
BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid... 177 8e-44
BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid... 177 8e-44
BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid... 177 8e-44
AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subu... 177 8e-44
X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1 su... 175 3e-43
M82919-1|AAA52511.1| 473|Homo sapiens GABA-alpha receptor beta-... 175 3e-43
M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid r... 175 3e-43
S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2 sub... 173 7e-43
S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2 sub... 173 7e-43
S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A... 173 7e-43
BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein. 173 7e-43
BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein. 173 7e-43
BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein. 173 7e-43
BC010641-1|AAH10641.1| 473|Homo sapiens gamma-aminobutyric acid... 172 2e-42
BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid... 170 9e-42
BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid... 170 9e-42
AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta s... 170 9e-42
AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta p... 170 9e-42
BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid... 169 1e-41
S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3 su... 164 6e-40
BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid... 164 6e-40
BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid... 164 6e-40
BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid... 164 6e-40
AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3 ... 164 6e-40
AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3 ... 164 6e-40
AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid... 164 6e-40
BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid... 163 1e-39
AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid... 163 1e-39
X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2 s... 163 1e-39
AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta s... 163 1e-39
Y07637-1|CAA68914.1| 505|Homo sapiens putative GABA-gated chlor... 159 2e-38
M86868-1|AAA52510.1| 465|Homo sapiens gamma-amino butyric acid ... 158 4e-38
M62400-1|AAA52509.1| 473|Homo sapiens gamma-aminobutyric acid r... 158 4e-38
BC130344-1|AAI30345.1| 474|Homo sapiens gamma-aminobutyric acid... 158 4e-38
AL353659-1|CAC36328.2| 473|Homo sapiens gamma-aminobutyric acid... 158 4e-38
AL353135-4|CAI16246.1| 473|Homo sapiens gamma-aminobutyric acid... 158 4e-38
BC130354-1|AAI30355.1| 465|Homo sapiens gamma-aminobutyric acid... 157 7e-38
BC130352-1|AAI30353.1| 465|Homo sapiens gamma-aminobutyric acid... 157 7e-38
AL121833-2|CAC07339.1| 465|Homo sapiens gamma-aminobutyric acid... 157 7e-38
Y09765-1|CAA70904.1| 506|Homo sapiens GABA receptor epsilon sub... 157 9e-38
U92283-1|AAB94645.1| 506|Homo sapiens GABA-A receptor epsilon s... 157 9e-38
U66661-1|AAB49284.1| 506|Homo sapiens GABA-A receptor epsilon s... 157 9e-38
Y09763-1|CAA70903.1| 506|Homo sapiens GABRE protein. 155 3e-37
BC059376-1|AAH59376.1| 365|Homo sapiens GABRE protein protein. 155 3e-37
BC047108-1|AAH47108.1| 365|Homo sapiens GABRE protein protein. 155 3e-37
BC026337-1|AAH26337.1| 365|Homo sapiens GABRE protein protein. 155 3e-37
BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid... 153 1e-36
S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid t... 147 7e-35
BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid... 147 7e-35
BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid... 147 7e-35
BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid... 147 7e-35
BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid... 147 7e-35
U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit al... 146 1e-34
L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine recep... 146 2e-34
BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid... 146 2e-34
BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid... 146 2e-34
BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid... 146 2e-34
BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid... 146 2e-34
BC022488-1|AAH22488.1| 367|Homo sapiens GABRA2 protein protein. 142 3e-33
S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA ... 141 4e-33
S62907-1|AAB27278.1| 451|Homo sapiens gamma-aminobutyric acidA ... 141 4e-33
BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid... 141 4e-33
AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit a... 141 4e-33
AB209295-1|BAD92532.1| 461|Homo sapiens gamma-aminobutyric acid... 141 4e-33
BC030696-1|AAH30696.1| 456|Homo sapiens GABRA1 protein protein. 138 3e-32
AK223447-1|BAD97167.1| 456|Homo sapiens gamma-aminobutyric acid... 138 3e-32
X14766-1|CAA32874.1| 456|Homo sapiens GABA-A receptor alpha 1 s... 133 1e-30
X13584-1|CAA31925.1| 354|Homo sapiens protein ( Human mRNA for ... 120 7e-27
AC093745-1|AAY40994.1| 222|Homo sapiens unknown protein. 112 3e-24
AF018157-1|AAC39918.1| 219|Homo sapiens glycine receptor alpha ... 105 3e-22
AC131948-1|AAY40916.1| 74|Homo sapiens unknown protein. 57 1e-07
X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for ... 55 5e-07
BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor, n... 54 7e-07
BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor, n... 54 7e-07
M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine r... 52 3e-06
BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine (se... 52 3e-06
BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine (se... 52 3e-06
AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin recep... 52 3e-06
AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin recep... 52 3e-06
AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine ser... 52 3e-06
Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine r... 51 9e-06
X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic acetyl... 51 9e-06
U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine r... 51 9e-06
M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic acetyl... 51 9e-06
BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor, n... 51 9e-06
BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor, n... 51 9e-06
BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor, n... 51 9e-06
BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein. 51 9e-06
BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor, n... 51 9e-06
BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor, n... 51 9e-06
BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor, n... 51 9e-06
AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine... 51 9e-06
AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic r... 51 9e-06
Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine r... 50 2e-05
Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine r... 50 2e-05
X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine re... 50 2e-05
X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine r... 50 2e-05
U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine r... 50 2e-05
U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine r... 50 2e-05
L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine r... 50 2e-05
DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor, n... 50 2e-05
BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor, n... 50 2e-05
BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor, n... 50 2e-05
AL121827-20|CAC36119.1| 627|Homo sapiens cholinergic receptor, ... 50 2e-05
AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine... 50 2e-05
Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor, nic... 49 4e-05
Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine r... 49 4e-05
X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic acetyl... 49 4e-05
U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine r... 49 4e-05
AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine... 49 4e-05
AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine rec... 49 4e-05
U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotini... 48 5e-05
BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine (se... 48 5e-05
AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic r... 48 5e-05
Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine r... 48 6e-05
U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine r... 48 6e-05
S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type ... 48 8e-05
D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor ... 48 8e-05
BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine (se... 48 8e-05
BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine (se... 48 8e-05
BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine (se... 48 8e-05
AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic acet... 48 8e-05
AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor pr... 48 8e-05
AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3 re... 48 8e-05
AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine rec... 48 8e-05
AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic acet... 47 1e-04
AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic acet... 47 1e-04
AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine... 47 1e-04
AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine... 47 1e-04
AM293589-1|CAL25321.1| 430|Homo sapiens 5-hydroxytryptamine rec... 47 1e-04
Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine r... 46 2e-04
U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine r... 46 2e-04
U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic acetylch... 46 2e-04
BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor, n... 46 2e-04
BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor, n... 46 2e-04
BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor, n... 46 2e-04
BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor, n... 46 2e-04
AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine... 46 2e-04
AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine... 46 2e-04
AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic acet... 46 2e-04
AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine... 46 2e-04
AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein. 46 2e-04
AF169255-1|AAF03691.1| 441|Homo sapiens 5-hydroxytryptamine 3 r... 46 3e-04
AF080582-1|AAD12242.1| 441|Homo sapiens 5-hydroxytryptamine 3 r... 46 3e-04
AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor prot... 44 0.001
AF228447-1|AAF62508.1| 96|Homo sapiens gamma-aminobutyric acid... 44 0.001
Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine r... 43 0.002
Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for ... 43 0.002
X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25... 43 0.002
X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor pr... 43 0.002
U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine r... 43 0.002
S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine r... 43 0.002
BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor, n... 43 0.002
BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor, n... 43 0.002
AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor, n... 43 0.002
AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein. 43 0.002
AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic acet... 43 0.002
AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein. 43 0.002
X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor ep... 43 0.002
AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor ... 43 0.002
X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4... 42 0.003
BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein. 42 0.004
Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine r... 42 0.005
X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor ga... 42 0.005
U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine r... 42 0.005
BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor, n... 42 0.005
AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic acet... 42 0.005
AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor prot... 42 0.005
AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein. 42 0.005
Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine r... 41 0.009
X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine ... 41 0.009
U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine r... 41 0.009
BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor, n... 41 0.009
BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor, n... 41 0.009
BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor, n... 41 0.009
AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine ... 41 0.009
M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha ... 40 0.012
AF228449-1|AAF62510.1| 70|Homo sapiens gamma-aminobutyric acid... 39 0.038
BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein. 38 0.050
X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor de... 37 0.12
BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor, n... 37 0.12
BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor, n... 37 0.12
AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein. 37 0.12
BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein. 31 7.6
BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein. 31 7.6
>X52009-1|CAA36258.1| 449|Homo sapiens inhibitory glycine receptor
protein.
Length = 449
Score = 208 bits (507), Expect = 4e-53
Identities = 105/289 (36%), Positives = 162/289 (56%), Gaps = 7/289 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL E DD + L
Sbjct: 58 PNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNE----YPDDSLDL 113
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K E+T + + RN V YS R+ +AC M+ + +
Sbjct: 114 DPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNF 173
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNGYMIDK 182
PMD+Q+C + +ESF Y+ + F W E G V + L L Q+ + + L +
Sbjct: 174 PMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHY--N 231
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G ++ + F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 232 TGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTM 291
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVF+AL E+ V + +Q++
Sbjct: 292 TTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK 340
Score = 33.1 bits (72), Expect = 1.9
Identities = 12/23 (52%), Positives = 17/23 (73%)
Query: 385 REIDKLSRVVFPALFLLFVTMYW 407
++IDK+SR+ FP FL+F YW
Sbjct: 413 KKIDKISRIGFPMAFLIFNMFYW 435
>X52008-1|CAA36257.1| 452|Homo sapiens inhibitory glycine receptor
protein.
Length = 452
Score = 208 bits (507), Expect = 4e-53
Identities = 106/291 (36%), Positives = 166/291 (57%), Gaps = 11/291 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ S+ MD+RV++F+RQ W++SRL E DD + L
Sbjct: 64 PNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSE----YPDDSLDL 119
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K ++T + + +N V YS R+ ++C M+ + +
Sbjct: 120 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 179
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMID- 181
PMD+Q+C + +ESF Y+ + F W S+ V + L L Q+ L+ E+ GY
Sbjct: 180 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFI----LKEEKELGYCTKH 235
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 236 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVL 295
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ V + +Q++
Sbjct: 296 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK 346
>U93917-1|AAC39917.1| 449|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 449
Score = 208 bits (507), Expect = 4e-53
Identities = 104/289 (35%), Positives = 164/289 (56%), Gaps = 7/289 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL E DD + L
Sbjct: 63 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE----YPDDSLDL 118
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K E+T + +++N V YS R+ ++C M+ + +
Sbjct: 119 DPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNF 178
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWS-EAGVTINPELKLLQYHIGQPLRLEETNGYMIDK 182
PMD+Q+C + +ESF Y+ + F W EA V + L L Q+ + + L +
Sbjct: 179 PMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHY--N 236
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 237 TGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTM 296
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVF+AL E+ V + +Q++
Sbjct: 297 TTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK 345
>U77731-1|AAB38272.1| 360|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 360
Score = 208 bits (507), Expect = 4e-53
Identities = 106/291 (36%), Positives = 166/291 (57%), Gaps = 11/291 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ S+ MD+RV++F+RQ W++SRL E DD + L
Sbjct: 64 PNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSE----YPDDSLDL 119
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K ++T + + +N V YS R+ ++C M+ + +
Sbjct: 120 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 179
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMID- 181
PMD+Q+C + +ESF Y+ + F W S+ V + L L Q+ L+ E+ GY
Sbjct: 180 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFI----LKEEKELGYCTKH 235
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 236 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVL 295
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ V + +Q++
Sbjct: 296 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK 346
>BC114947-1|AAI14948.1| 457|Homo sapiens GLRA1 protein protein.
Length = 457
Score = 208 bits (507), Expect = 4e-53
Identities = 105/289 (36%), Positives = 162/289 (56%), Gaps = 7/289 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL E DD + L
Sbjct: 58 PNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNE----YPDDSLDL 113
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K E+T + + RN V YS R+ +AC M+ + +
Sbjct: 114 DPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNF 173
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNGYMIDK 182
PMD+Q+C + +ESF Y+ + F W E G V + L L Q+ + + L +
Sbjct: 174 PMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHY--N 231
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G ++ + F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 232 TGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTM 291
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVF+AL E+ V + +Q++
Sbjct: 292 TTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK 340
Score = 33.1 bits (72), Expect = 1.9
Identities = 12/23 (52%), Positives = 17/23 (73%)
Query: 385 REIDKLSRVVFPALFLLFVTMYW 407
++IDK+SR+ FP FL+F YW
Sbjct: 421 KKIDKISRIGFPMAFLIFNMFYW 443
>BC074980-1|AAH74980.1| 449|Homo sapiens glycine receptor, alpha 1
(startle disease/hyperekplexia, stiff man syndrome)
protein.
Length = 449
Score = 208 bits (507), Expect = 4e-53
Identities = 105/289 (36%), Positives = 162/289 (56%), Gaps = 7/289 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL E DD + L
Sbjct: 58 PNFKGPPVNVSCNIFINSFGSIAETTMDYRVNIFLRQQWNDPRLAYNE----YPDDSLDL 113
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K E+T + + RN V YS R+ +AC M+ + +
Sbjct: 114 DPSMLDSIWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNF 173
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAG-VTINPELKLLQYHIGQPLRLEETNGYMIDK 182
PMD+Q+C + +ESF Y+ + F W E G V + L L Q+ + + L +
Sbjct: 174 PMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEEKDLRYCTKHY--N 231
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G ++ + F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 232 TGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGITTVLTM 291
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVF+AL E+ V + +Q++
Sbjct: 292 TTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK 340
Score = 33.1 bits (72), Expect = 1.9
Identities = 12/23 (52%), Positives = 17/23 (73%)
Query: 385 REIDKLSRVVFPALFLLFVTMYW 407
++IDK+SR+ FP FL+F YW
Sbjct: 413 KKIDKISRIGFPMAFLIFNMFYW 435
>BC036086-1|AAH36086.1| 464|Homo sapiens glycine receptor, alpha 3
protein.
Length = 464
Score = 208 bits (507), Expect = 4e-53
Identities = 104/289 (35%), Positives = 164/289 (56%), Gaps = 7/289 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL E DD + L
Sbjct: 63 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE----YPDDSLDL 118
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K E+T + +++N V YS R+ ++C M+ + +
Sbjct: 119 DPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNF 178
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWS-EAGVTINPELKLLQYHIGQPLRLEETNGYMIDK 182
PMD+Q+C + +ESF Y+ + F W EA V + L L Q+ + + L +
Sbjct: 179 PMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHY--N 236
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 237 TGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTM 296
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVF+AL E+ V + +Q++
Sbjct: 297 TTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK 345
>BC032864-1|AAH32864.1| 452|Homo sapiens glycine receptor, alpha 2
protein.
Length = 452
Score = 208 bits (507), Expect = 4e-53
Identities = 106/291 (36%), Positives = 166/291 (57%), Gaps = 11/291 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ S+ MD+RV++F+RQ W++SRL E DD + L
Sbjct: 64 PNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSE----YPDDSLDL 119
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K ++T + + +N V YS R+ ++C M+ + +
Sbjct: 120 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 179
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMID- 181
PMD+Q+C + +ESF Y+ + F W S+ V + L L Q+ L+ E+ GY
Sbjct: 180 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFI----LKEEKELGYCTKH 235
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 236 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVL 295
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ V + +Q++
Sbjct: 296 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK 346
>AY437083-1|AAR87842.1| 452|Homo sapiens glycine receptor alpha2
subunit A protein.
Length = 452
Score = 208 bits (507), Expect = 4e-53
Identities = 106/291 (36%), Positives = 166/291 (57%), Gaps = 11/291 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ S+ MD+RV++F+RQ W++SRL E DD + L
Sbjct: 64 PNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSE----YPDDSLDL 119
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K ++T + + +N V YS R+ ++C M+ + +
Sbjct: 120 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 179
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMID- 181
PMD+Q+C + +ESF Y+ + F W S+ V + L L Q+ L+ E+ GY
Sbjct: 180 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFI----LKEEKELGYCTKH 235
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 236 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVL 295
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ V + +Q++
Sbjct: 296 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK 346
>AF053495-1|AAC35290.1| 452|Homo sapiens glycine receptor alpha 2
subunit protein.
Length = 452
Score = 208 bits (507), Expect = 4e-53
Identities = 106/291 (36%), Positives = 166/291 (57%), Gaps = 11/291 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ S+ MD+RV++F+RQ W++SRL E DD + L
Sbjct: 64 PNFKGPPVNVTCNIFINSFGSVTETTMDYRVNIFLRQQWNDSRLAYSE----YPDDSLDL 119
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K ++T + + +N V YS R+ ++C M+ + +
Sbjct: 120 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 179
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMID- 181
PMD+Q+C + +ESF Y+ + F W S+ V + L L Q+ L+ E+ GY
Sbjct: 180 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFI----LKEEKELGYCTKH 235
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 236 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVL 295
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ V + +Q++
Sbjct: 296 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK 346
>AF017724-1|AAC39919.1| 465|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 465
Score = 208 bits (507), Expect = 4e-53
Identities = 104/289 (35%), Positives = 164/289 (56%), Gaps = 7/289 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL E DD + L
Sbjct: 63 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRLAYSE----YPDDSLDL 118
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K E+T + +++N V YS R+ ++C M+ + +
Sbjct: 119 DPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLTLSCPMDLKNF 178
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWS-EAGVTINPELKLLQYHIGQPLRLEETNGYMIDK 182
PMD+Q+C + +ESF Y+ + F W EA V + L L Q+ + + L +
Sbjct: 179 PMDVQTCIMQLESFGYTMNDLIFEWQDEAPVQVAEGLTLPQFLLKEEKDLRYCTKHY--N 236
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 237 TGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTM 296
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVF+AL E+ V + +Q++
Sbjct: 297 TTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK 345
>Z93848-1|CAI41994.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 207 bits (506), Expect = 5e-53
Identities = 105/290 (36%), Positives = 165/290 (56%), Gaps = 8/290 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ +SI MD+RV++F+RQ W++ RL E DD + L
Sbjct: 23 PNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYRE----YPDDSLDL 78
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K E+T + +++N V YS R+ I++C M+ + +
Sbjct: 79 DPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNF 138
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSE--AGVTINPELKLLQYHIGQPLRLEETNGYMID 181
PMDIQ+C + +ESF Y+ + + F W E V + L L Q+ + L +
Sbjct: 139 PMDIQTCTMQLESFGYTMKDLVFEWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHY-- 196
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 197 NTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLT 256
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ + + +Q++
Sbjct: 257 MTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAINFVSRQHK 306
>U77731-2|AAB38273.1| 360|Homo sapiens glycine receptor alpha 2B
subunit protein.
Length = 360
Score = 207 bits (506), Expect = 5e-53
Identities = 107/291 (36%), Positives = 166/291 (57%), Gaps = 11/291 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++SRL E DD + L
Sbjct: 64 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSE----YPDDSLDL 119
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K ++T + + +N V YS R+ ++C M+ + +
Sbjct: 120 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 179
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMID- 181
PMD+Q+C + +ESF Y+ + F W S+ V + L L Q+ L+ E+ GY
Sbjct: 180 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFI----LKEEKELGYCTKH 235
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 236 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVL 295
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ V + +Q++
Sbjct: 296 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK 346
>CR450343-1|CAG29339.1| 452|Homo sapiens GLRA2 protein.
Length = 452
Score = 207 bits (506), Expect = 5e-53
Identities = 107/291 (36%), Positives = 166/291 (57%), Gaps = 11/291 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++SRL E DD + L
Sbjct: 64 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSE----YPDDSLDL 119
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K ++T + + +N V YS R+ ++C M+ + +
Sbjct: 120 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 179
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMID- 181
PMD+Q+C + +ESF Y+ + F W S+ V + L L Q+ L+ E+ GY
Sbjct: 180 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFI----LKEEKELGYCTKH 235
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 236 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVL 295
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ V + +Q++
Sbjct: 296 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK 346
>AY437084-1|AAR87843.1| 452|Homo sapiens glycine receptor alpha2
subunit B protein.
Length = 452
Score = 207 bits (506), Expect = 5e-53
Identities = 107/291 (36%), Positives = 166/291 (57%), Gaps = 11/291 (3%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++SRL E DD + L
Sbjct: 64 PNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDSRLAYSE----YPDDSLDL 119
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K ++T + + +N V YS R+ ++C M+ + +
Sbjct: 120 DPSMLDSIWKPDLFFANEKGANFHDVTTDNKLLRISKNGKVLYSIRLTLTLSCPMDLKNF 179
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMID- 181
PMD+Q+C + +ESF Y+ + F W S+ V + L L Q+ L+ E+ GY
Sbjct: 180 PMDVQTCTMQLESFGYTMNDLIFEWLSDGPVQVAEGLTLPQFI----LKEEKELGYCTKH 235
Query: 182 -KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXX 240
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 236 YNTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVL 295
Query: 241 XXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ V + +Q++
Sbjct: 296 TMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAVNFVSRQHK 346
>AL049610-1|CAI42158.1| 376|Homo sapiens glycine receptor, alpha 4
protein.
Length = 376
Score = 207 bits (506), Expect = 5e-53
Identities = 105/290 (36%), Positives = 165/290 (56%), Gaps = 8/290 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ +SI MD+RV++F+RQ W++ RL E DD + L
Sbjct: 23 PNFKGPPVNVTCNIFINSFSSITKTTMDYRVNVFLRQQWNDPRLSYRE----YPDDSLDL 78
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P D++W PD +F N K E+T + +++N V YS R+ I++C M+ + +
Sbjct: 79 DPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLTLILSCLMDLKNF 138
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSE--AGVTINPELKLLQYHIGQPLRLEETNGYMID 181
PMDIQ+C + +ESF Y+ + + F W E V + L L Q+ + L +
Sbjct: 139 PMDIQTCTMQLESFGYTMKDLVFEWLEDAPAVQVAEGLTLPQFILRDEKDLGCCTKHY-- 196
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
G ++ + V F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R
Sbjct: 197 NTGKFTCIEVKFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLGITTVLT 256
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+G RA +P V+YVKA+D+WMA C++FVFAAL E+ + + +Q++
Sbjct: 257 MTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFAALLEYAAINFVSRQHK 306
>BC114967-1|AAI14968.1| 366|Homo sapiens GLRA1 protein protein.
Length = 366
Score = 195 bits (476), Expect = 2e-49
Identities = 96/263 (36%), Positives = 150/263 (57%), Gaps = 7/263 (2%)
Query: 30 MDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAEL 89
MD+RV++F+RQ W++ RL E DD + L P D++W PD +F N K E+
Sbjct: 1 MDYRVNIFLRQQWNDPRLAYNE----YPDDSLDLDPSMLDSIWKPDLFFANEKGAHFHEI 56
Query: 90 THKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIESFSYSNQKVRFRWS 149
T + + RN V YS R+ +AC M+ + +PMD+Q+C + +ESF Y+ + F W
Sbjct: 57 TTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ 116
Query: 150 EAG-VTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRLVVYFRFERQIGHHLIQTFA 208
E G V + L L Q+ + + L + G ++ + F ERQ+G++LIQ +
Sbjct: 117 EQGAVQVADGLTLPQFILKEEKDLRYCTKHY--NTGKFTCIEARFHLERQMGYYLIQMYI 174
Query: 209 PSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRADIPPVAYVKALDLWMAG 268
PS L+V+LSW SFW+++DA P R +G RA +P V+YVKA+D+WMA
Sbjct: 175 PSLLIVILSWISFWINMDAAPARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAV 234
Query: 269 CMMFVFAALGEFVVVKVLDKQYQ 291
C++FVF+AL E+ V + +Q++
Sbjct: 235 CLLFVFSALLEYAAVNFVSRQHK 257
Score = 33.1 bits (72), Expect = 1.9
Identities = 12/23 (52%), Positives = 17/23 (73%)
Query: 385 REIDKLSRVVFPALFLLFVTMYW 407
++IDK+SR+ FP FL+F YW
Sbjct: 330 KKIDKISRIGFPMAFLIFNMFYW 352
>U33267-1|AAB37750.1| 497|Homo sapiens glycine receptor beta
subunit protein.
Length = 497
Score = 193 bits (471), Expect = 8e-49
Identities = 99/284 (34%), Positives = 158/284 (55%), Gaps = 4/284 (1%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL+LP D G D +T+
Sbjct: 73 PNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDF--RGSDALTV 130
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P + LW PD +F N K ++T + + ++R+ V S R+ ++C ++ L+
Sbjct: 131 DPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLF 190
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD 183
PMD Q C + +ESF Y+ +RF W ++ L Q+ I + +E N K
Sbjct: 191 PMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKE-DIEYGNCTKYYKG 249
Query: 184 -GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+ + V F RQ+G +++ +AP+ L+V+LSW SFW++ DA R
Sbjct: 250 TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSL 309
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T L A++P V+YVKALD+W+ C++F FA+L E+ VV+V+
Sbjct: 310 ASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVM 353
>BC032635-1|AAH32635.1| 497|Homo sapiens glycine receptor, beta
protein.
Length = 497
Score = 193 bits (471), Expect = 8e-49
Identities = 99/284 (34%), Positives = 158/284 (55%), Gaps = 4/284 (1%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL+LP D G D +T+
Sbjct: 73 PNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDF--RGSDALTV 130
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P + LW PD +F N K ++T + + ++R+ V S R+ ++C ++ L+
Sbjct: 131 DPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLF 190
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD 183
PMD Q C + +ESF Y+ +RF W ++ L Q+ I + +E N K
Sbjct: 191 PMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKE-DIEYGNCTKYYKG 249
Query: 184 -GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+ + V F RQ+G +++ +AP+ L+V+LSW SFW++ DA R
Sbjct: 250 TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSL 309
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T L A++P V+YVKALD+W+ C++F FA+L E+ VV+V+
Sbjct: 310 ASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVM 353
>AF094755-1|AAC71034.1| 497|Homo sapiens glycine receptor beta
subunit precursor protein.
Length = 497
Score = 193 bits (471), Expect = 8e-49
Identities = 99/284 (34%), Positives = 158/284 (55%), Gaps = 4/284 (1%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL+LP D G D +T+
Sbjct: 73 PNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDF--RGSDALTV 130
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P + LW PD +F N K ++T + + ++R+ V S R+ ++C ++ L+
Sbjct: 131 DPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLF 190
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD 183
PMD Q C + +ESF Y+ +RF W ++ L Q+ I + +E N K
Sbjct: 191 PMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKE-DIEYGNCTKYYKG 249
Query: 184 -GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+ + V F RQ+G +++ +AP+ L+V+LSW SFW++ DA R
Sbjct: 250 TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSL 309
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T L A++P V+YVKALD+W+ C++F FA+L E+ VV+V+
Sbjct: 310 ASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVM 353
>AF094754-1|AAC71033.1| 497|Homo sapiens glycine receptor beta
subunit precursor protein.
Length = 497
Score = 193 bits (471), Expect = 8e-49
Identities = 99/284 (34%), Positives = 158/284 (55%), Gaps = 4/284 (1%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P KG PV V +I++ SI MD+RV++F+RQ W++ RL+LP D G D +T+
Sbjct: 73 PNFKGIPVDVVVNIFINSFGSIQETTMDYRVNIFLRQKWNDPRLKLPSDF--RGSDALTV 130
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
P + LW PD +F N K ++T + + ++R+ V S R+ ++C ++ L+
Sbjct: 131 DPTMYKCLWKPDLFFANEKSANFHDVTQENILLFIFRDGDVLVSMRLSITLSCPLDLTLF 190
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD 183
PMD Q C + +ESF Y+ +RF W ++ L Q+ I + +E N K
Sbjct: 191 PMDTQRCKMQLESFGYTTDDLRFIWQSGDPVQLEKIALPQFDIKKE-DIEYGNCTKYYKG 249
Query: 184 -GNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+ + V F RQ+G +++ +AP+ L+V+LSW SFW++ DA R
Sbjct: 250 TGYYTCVEVIFTLRRQVGFYMMGVYAPTLLIVVLSWLSFWINPDASAARVPLGIFSVLSL 309
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T L A++P V+YVKALD+W+ C++F FA+L E+ VV+V+
Sbjct: 310 ASECTTLAAELPKVSYVKALDVWLIACLLFGFASLVEYAVVQVM 353
>U95367-1|AAC51357.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 177 bits (430), Expect = 8e-44
Identities = 91/292 (31%), Positives = 152/292 (52%), Gaps = 12/292 (4%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G+PV + ++ + ++SI+ +MD+ +++RQ W + RL +FE G+ TL
Sbjct: 58 GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRL-----VFE-GNKSFTLDARL 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD Y + SK + + E+T + L+ N TV Y+ R+ +AC M+ YPMD
Sbjct: 112 VEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDT 171
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + +ES+ Y V F W ++ L+L QY I + L + + GN
Sbjct: 172 QTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQ---QETGN 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y+RLV+ F R + + +++T+ PS+ +V+LSW SFW+ LD++P R
Sbjct: 229 YTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTL 288
Query: 246 FTGLRADIPPV-AYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
G R +P ++KA+D+++ C FVF AL E+ V Q K++
Sbjct: 289 MIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
>BC109106-1|AAI09107.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 177 bits (430), Expect = 8e-44
Identities = 91/292 (31%), Positives = 152/292 (52%), Gaps = 12/292 (4%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G+PV + ++ + ++SI+ +MD+ +++RQ W + RL +FE G+ TL
Sbjct: 58 GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRL-----VFE-GNKSFTLDARL 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD Y + SK + + E+T + L+ N TV Y+ R+ +AC M+ YPMD
Sbjct: 112 VEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDT 171
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + +ES+ Y V F W ++ L+L QY I + L + + GN
Sbjct: 172 QTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQ---QETGN 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y+RLV+ F R + + +++T+ PS+ +V+LSW SFW+ LD++P R
Sbjct: 229 YTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTL 288
Query: 246 FTGLRADIPPV-AYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
G R +P ++KA+D+++ C FVF AL E+ V Q K++
Sbjct: 289 MIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
>BC109105-1|AAI09106.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 177 bits (430), Expect = 8e-44
Identities = 91/292 (31%), Positives = 152/292 (52%), Gaps = 12/292 (4%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G+PV + ++ + ++SI+ +MD+ +++RQ W + RL +FE G+ TL
Sbjct: 58 GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRL-----VFE-GNKSFTLDARL 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD Y + SK + + E+T + L+ N TV Y+ R+ +AC M+ YPMD
Sbjct: 112 VEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDT 171
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + +ES+ Y V F W ++ L+L QY I + L + + GN
Sbjct: 172 QTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQ---QETGN 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y+RLV+ F R + + +++T+ PS+ +V+LSW SFW+ LD++P R
Sbjct: 229 YTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTL 288
Query: 246 FTGLRADIPPV-AYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
G R +P ++KA+D+++ C FVF AL E+ V Q K++
Sbjct: 289 MIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
>BC074865-1|AAH74865.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 177 bits (430), Expect = 8e-44
Identities = 91/292 (31%), Positives = 152/292 (52%), Gaps = 12/292 (4%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G+PV + ++ + ++SI+ +MD+ +++RQ W + RL +FE G+ TL
Sbjct: 58 GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRL-----VFE-GNKSFTLDARL 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD Y + SK + + E+T + L+ N TV Y+ R+ +AC M+ YPMD
Sbjct: 112 VEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDT 171
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + +ES+ Y V F W ++ L+L QY I + L + + GN
Sbjct: 172 QTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQ---QETGN 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y+RLV+ F R + + +++T+ PS+ +V+LSW SFW+ LD++P R
Sbjct: 229 YTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTL 288
Query: 246 FTGLRADIPPV-AYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
G R +P ++KA+D+++ C FVF AL E+ V Q K++
Sbjct: 289 MIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
>BC074810-1|AAH74810.1| 440|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, pi protein.
Length = 440
Score = 177 bits (430), Expect = 8e-44
Identities = 91/292 (31%), Positives = 152/292 (52%), Gaps = 12/292 (4%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G+PV + ++ + ++SI+ +MD+ +++RQ W + RL +FE G+ TL
Sbjct: 58 GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRL-----VFE-GNKSFTLDARL 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD Y + SK + + E+T + L+ N TV Y+ R+ +AC M+ YPMD
Sbjct: 112 VEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDT 171
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + +ES+ Y V F W ++ L+L QY I + L + + GN
Sbjct: 172 QTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQ---QETGN 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y+RLV+ F R + + +++T+ PS+ +V+LSW SFW+ LD++P R
Sbjct: 229 YTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTL 288
Query: 246 FTGLRADIPPV-AYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
G R +P ++KA+D+++ C FVF AL E+ V Q K++
Sbjct: 289 MIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
>AF009702-1|AAC24194.1| 440|Homo sapiens GABA-A receptor pi subunit
protein.
Length = 440
Score = 177 bits (430), Expect = 8e-44
Identities = 91/292 (31%), Positives = 152/292 (52%), Gaps = 12/292 (4%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G+PV + ++ + ++SI+ +MD+ +++RQ W + RL +FE G+ TL
Sbjct: 58 GEPVQIALTLDIASISSISESNMDYTATIYLRQRWMDQRL-----VFE-GNKSFTLDARL 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD Y + SK + + E+T + L+ N TV Y+ R+ +AC M+ YPMD
Sbjct: 112 VEFLWVPDTYIVESKKSFLHEVTVGNRLIRLFSNGTVLYALRITTTVACNMDLSKYPMDT 171
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + +ES+ Y V F W ++ L+L QY I + L + + GN
Sbjct: 172 QTCKLQLESWGYDGNDVEFTWLRGNDSVRGLEHLRLAQYTIERYFTLVTRSQ---QETGN 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y+RLV+ F R + + +++T+ PS+ +V+LSW SFW+ LD++P R
Sbjct: 229 YTRLVLQFELRRNVLYFILETYVPSTFLVVLSWVSFWISLDSVPARTCIGVTTVLSMTTL 288
Query: 246 FTGLRADIPPV-AYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
G R +P ++KA+D+++ C FVF AL E+ V Q K++
Sbjct: 289 MIGSRTSLPNTNCFIKAIDVYLGICFSFVFGALLEYAVAHYSSLQQMAAKDR 340
>X14767-1|CAA32875.1| 474|Homo sapiens GABA-A receptor beta 1
subunit protein.
Length = 474
Score = 175 bits (425), Expect = 3e-43
Identities = 93/281 (33%), Positives = 150/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V I V ++ ++ +MD+ + M+ +Q+W + RL + ++TL
Sbjct: 58 GPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLS-----YSGIPLNLTLDNRV 112
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 113 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 172
Query: 128 QSCPIYIESFSYSNQKVRFRWS--EAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W+ E VT +++L Q+ I + + + G
Sbjct: 173 QNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTT---GA 229
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + FR +R IG+ ++QT+ PS+L+ +LSW SFW++ DA R
Sbjct: 230 YPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTI 289
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ V +
Sbjct: 290 STHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYI 330
>M82919-1|AAA52511.1| 473|Homo sapiens GABA-alpha receptor beta-3
subunit protein.
Length = 473
Score = 175 bits (425), Expect = 3e-43
Identities = 94/281 (33%), Positives = 150/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V +I + ++ ++ +MD+ + M+ +Q W + RL + ++TL
Sbjct: 58 GPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLA-----YSGIPLNLTLDNRV 112
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 113 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 172
Query: 128 QSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W + VT ++L Q+ I + RL N ++ G
Sbjct: 173 QNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH-RLVSRN--VVFATGA 229
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + FR +R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 230 YPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTI 289
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ V +
Sbjct: 290 NTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330
>M59216-1|AAA35862.1| 474|Homo sapiens gamma-aminobutyric acid
receptor beta-1 subunit protein.
Length = 474
Score = 175 bits (425), Expect = 3e-43
Identities = 93/281 (33%), Positives = 150/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V I V ++ ++ +MD+ + M+ +Q+W + RL + ++TL
Sbjct: 58 GPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLS-----YSGIPLNLTLDNRV 112
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 113 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 172
Query: 128 QSCPIYIESFSYSNQKVRFRWS--EAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W+ E VT +++L Q+ I + + + G
Sbjct: 173 QNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTT---GA 229
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + FR +R IG+ ++QT+ PS+L+ +LSW SFW++ DA R
Sbjct: 230 YPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTI 289
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ V +
Sbjct: 290 STHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYI 330
>S77554-1|AAB33983.1| 474|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 474
Score = 173 bits (422), Expect = 7e-43
Identities = 90/281 (32%), Positives = 151/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V +I + ++ ++ +MD+ + M+ +Q W + RL + ++TL
Sbjct: 57 GPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLS-----YNVIPLNLTLDNRV 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 112 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 171
Query: 128 QSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W + VT +++L Q+ I + + ++ G+
Sbjct: 172 QNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKK---VVFSTGS 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + F+ +R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 229 YPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTI 288
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ +V +
Sbjct: 289 NTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
>S77553-1|AAB33982.1| 512|Homo sapiens GABAA receptor beta 2
subunit protein.
Length = 512
Score = 173 bits (422), Expect = 7e-43
Identities = 90/281 (32%), Positives = 151/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V +I + ++ ++ +MD+ + M+ +Q W + RL + ++TL
Sbjct: 57 GPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLS-----YNVIPLNLTLDNRV 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 112 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 171
Query: 128 QSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W + VT +++L Q+ I + + ++ G+
Sbjct: 172 QNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKK---VVFSTGS 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + F+ +R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 229 YPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTI 288
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ +V +
Sbjct: 289 NTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
>S67368-1|AAB29370.1| 474|Homo sapiens gamma-aminobutyric acid A
receptor beta 2 subunit protein.
Length = 474
Score = 173 bits (422), Expect = 7e-43
Identities = 90/281 (32%), Positives = 151/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V +I + ++ ++ +MD+ + M+ +Q W + RL + ++TL
Sbjct: 57 GPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLS-----YNVIPLNLTLDNRV 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 112 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 171
Query: 128 QSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W + VT +++L Q+ I + + ++ G+
Sbjct: 172 QNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKK---VVFSTGS 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + F+ +R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 229 YPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTI 288
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ +V +
Sbjct: 289 NTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
>BC105639-1|AAI05640.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 173 bits (422), Expect = 7e-43
Identities = 90/281 (32%), Positives = 151/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V +I + ++ ++ +MD+ + M+ +Q W + RL + ++TL
Sbjct: 57 GPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLS-----YNVIPLNLTLDNRV 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 112 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 171
Query: 128 QSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W + VT +++L Q+ I + + ++ G+
Sbjct: 172 QNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKK---VVFSTGS 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + F+ +R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 229 YPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTI 288
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ +V +
Sbjct: 289 NTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
>BC099719-1|AAH99719.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 173 bits (422), Expect = 7e-43
Identities = 90/281 (32%), Positives = 151/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V +I + ++ ++ +MD+ + M+ +Q W + RL + ++TL
Sbjct: 57 GPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLS-----YNVIPLNLTLDNRV 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 112 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 171
Query: 128 QSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W + VT +++L Q+ I + + ++ G+
Sbjct: 172 QNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKK---VVFSTGS 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + F+ +R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 229 YPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTI 288
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ +V +
Sbjct: 289 NTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
>BC099705-1|AAH99705.1| 474|Homo sapiens GABRB2 protein protein.
Length = 474
Score = 173 bits (422), Expect = 7e-43
Identities = 90/281 (32%), Positives = 151/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V +I + ++ ++ +MD+ + M+ +Q W + RL + ++TL
Sbjct: 57 GPPVAVGMNIDIASIDMVSEVNMDYTLTMYFQQAWRDKRLS-----YNVIPLNLTLDNRV 111
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 112 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 171
Query: 128 QSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W + VT +++L Q+ I + + ++ G+
Sbjct: 172 QNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTKIELPQFSIVDYKLITKK---VVFSTGS 228
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + F+ +R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 229 YPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTI 288
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ +V +
Sbjct: 289 NTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYALVNYI 329
>BC010641-1|AAH10641.1| 473|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 3 protein.
Length = 473
Score = 172 bits (418), Expect = 2e-42
Identities = 93/281 (33%), Positives = 149/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V +I + ++ ++ +MD+ + M+ +Q W + RL + ++TL
Sbjct: 58 GPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLA-----YSGIPLNLTLDNRV 112
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D LW PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 113 ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 172
Query: 128 QSCPIYIESFSYSNQKVRFRW--SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
+C + IES+ Y+ + F W + VT ++L Q+ I + RL N ++ G
Sbjct: 173 LNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH-RLVSRN--VVFATGA 229
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + FR +R IG+ ++QT+ PS L+ +LSW SFW++ DA R
Sbjct: 230 YPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTI 289
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ V +
Sbjct: 290 NTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330
>BC109211-1|AAI09212.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 170 bits (413), Expect = 9e-42
Identities = 92/304 (30%), Positives = 157/304 (51%), Gaps = 12/304 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V SIYV + I+ +MD+ + MF QTW +SRL E ++TL
Sbjct: 80 GAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETTL-----NLTLDYRM 134
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD YFLNSK + ++T + L+ + TVRY R+ AC ++ +PMD
Sbjct: 135 HEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDK 194
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQY-HIGQPLRLEETNGYMIDKDG 184
Q+C + +ES+ Y+ + + W + G I+ EL + Q+ +G+ + +E Y G
Sbjct: 195 QACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYT----G 250
Query: 185 NYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXX 244
+Y RL++ F+ +R++ +L+Q + P+ L + SW SFW++ D+ R
Sbjct: 251 SYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTT 310
Query: 245 XFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRI 304
+ LR +P ++ +KA+D+++ C+ FVF +L E+V + L + + PR
Sbjct: 311 IDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRPRR 370
Query: 305 IPVR 308
+ R
Sbjct: 371 VIAR 374
>BC109210-1|AAI09211.1| 632|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, theta protein.
Length = 632
Score = 170 bits (413), Expect = 9e-42
Identities = 92/304 (30%), Positives = 157/304 (51%), Gaps = 12/304 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V SIYV + I+ +MD+ + MF QTW +SRL E ++TL
Sbjct: 80 GAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETTL-----NLTLDYRM 134
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD YFLNSK + ++T + L+ + TVRY R+ AC ++ +PMD
Sbjct: 135 HEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDK 194
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQY-HIGQPLRLEETNGYMIDKDG 184
Q+C + +ES+ Y+ + + W + G I+ EL + Q+ +G+ + +E Y G
Sbjct: 195 QACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYT----G 250
Query: 185 NYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXX 244
+Y RL++ F+ +R++ +L+Q + P+ L + SW SFW++ D+ R
Sbjct: 251 SYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTT 310
Query: 245 XFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRI 304
+ LR +P ++ +KA+D+++ C+ FVF +L E+V + L + + PR
Sbjct: 311 IDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRPRR 370
Query: 305 IPVR 308
+ R
Sbjct: 371 VIAR 374
>AF189259-1|AAF70380.1| 632|Homo sapiens GABA-A receptor theta
subunit protein.
Length = 632
Score = 170 bits (413), Expect = 9e-42
Identities = 92/304 (30%), Positives = 157/304 (51%), Gaps = 12/304 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V SIYV + I+ +MD+ + MF QTW +SRL E ++TL
Sbjct: 80 GAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETTL-----NLTLDYRM 134
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD YFLNSK + ++T + L+ + TVRY R+ AC ++ +PMD
Sbjct: 135 HEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDK 194
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQY-HIGQPLRLEETNGYMIDKDG 184
Q+C + +ES+ Y+ + + W + G I+ EL + Q+ +G+ + +E Y G
Sbjct: 195 QACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYT----G 250
Query: 185 NYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXX 244
+Y RL++ F+ +R++ +L+Q + P+ L + SW SFW++ D+ R
Sbjct: 251 SYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTT 310
Query: 245 XFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRI 304
+ LR +P ++ +KA+D+++ C+ FVF +L E+V + L + + PR
Sbjct: 311 IDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRPRR 370
Query: 305 IPVR 308
+ R
Sbjct: 371 VIAR 374
>AF144648-1|AAD51172.1| 627|Homo sapiens GABA-A receptor theta
protein.
Length = 627
Score = 170 bits (413), Expect = 9e-42
Identities = 92/304 (30%), Positives = 157/304 (51%), Gaps = 12/304 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V SIYV + I+ +MD+ + MF QTW +SRL E ++TL
Sbjct: 75 GAPVPVRISIYVTSIEQISEMNMDYTITMFFHQTWKDSRLAYYETTL-----NLTLDYRM 129
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
+ LW PD YFLNSK + ++T + L+ + TVRY R+ AC ++ +PMD
Sbjct: 130 HEKLWVPDCYFLNSKDAFVHDVTVENRVFQLHPDGTVRYGIRLTTTAACSLDLHKFPMDK 189
Query: 128 QSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQY-HIGQPLRLEETNGYMIDKDG 184
Q+C + +ES+ Y+ + + W + G I+ EL + Q+ +G+ + +E Y G
Sbjct: 190 QACNLVVESYGYTVEDIILFWDDNGNAIHMTEELHIPQFTFLGRTITSKEVYFYT----G 245
Query: 185 NYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXX 244
+Y RL++ F+ +R++ +L+Q + P+ L + SW SFW++ D+ R
Sbjct: 246 SYIRLILKFQVQREVNSYLVQVYWPTVLTTITSWISFWMNYDSSAARVTIGLTSMLILTT 305
Query: 245 XFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRI 304
+ LR +P ++ +KA+D+++ C+ FVF +L E+V + L + + PR
Sbjct: 306 IDSHLRDKLPNISCIKAIDIYILVCLFFVFLSLLEYVYINYLFYSRGPRRQPRRHRRPRR 365
Query: 305 IPVR 308
+ R
Sbjct: 366 VIAR 369
>BC022449-1|AAH22449.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, beta 1 protein.
Length = 474
Score = 169 bits (412), Expect = 1e-41
Identities = 92/281 (32%), Positives = 149/281 (53%), Gaps = 10/281 (3%)
Query: 8 GQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEF 67
G PV V I V ++ ++ +MD+ + M+ +Q+W + RL + ++TL
Sbjct: 58 GPPVDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLS-----YSGIPLNLTLDNRV 112
Query: 68 FDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDI 127
D L PD YFLN K + + +T K + L+ + TV Y R+ AC M+ + YP+D
Sbjct: 113 ADQLCVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDE 172
Query: 128 QSCPIYIESFSYSNQKVRFRWS--EAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN 185
Q+C + IES+ Y+ + F W+ E VT +++L Q+ I + + + G
Sbjct: 173 QNCTLEIESYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTT---GA 229
Query: 186 YSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXX 245
Y RL + FR +R IG+ ++QT+ PS+L+ +LSW SFW++ DA R
Sbjct: 230 YPRLSLSFRLKRNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTI 289
Query: 246 FTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T LR +P + YVKA+D+++ GC +FVF AL E+ V +
Sbjct: 290 STHLRETLPKIPYVKAIDIYLMGCFVFVFLALLEYAFVNYI 330
>S82769-1|AAB39369.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 164 bits (398), Expect = 6e-40
Identities = 82/275 (29%), Positives = 138/275 (50%), Gaps = 6/275 (2%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +++ IYV + ++ +M++++D+F QTW++SRL+ F +TL
Sbjct: 69 KPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLR-----FNSTMKILTLNSNMV 123
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD F NSK E +T + ++ + + Y+ R+ CQ++ +PMD
Sbjct: 124 GLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEH 183
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
SCP+ S+ Y +++ +RW + V + Y + L T + G+Y
Sbjct: 184 SCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDF-MGLRNTTEIVTTSAGDYVV 242
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ +YF R++G+ IQT+ P L V+LSW SFW+ DA P R T
Sbjct: 243 MTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTI 302
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
R +P V+YV A+DL++ C +FVFAAL E+ +
Sbjct: 303 ARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
Score = 32.3 bits (70), Expect = 3.3
Identities = 13/22 (59%), Positives = 15/22 (68%)
Query: 386 EIDKLSRVVFPALFLLFVTMYW 407
E+D SRV FP FLLF +YW
Sbjct: 440 ELDSYSRVFFPTSFLLFNLVYW 461
>BC074795-1|AAH74795.1| 467|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 467
Score = 164 bits (398), Expect = 6e-40
Identities = 84/302 (27%), Positives = 153/302 (50%), Gaps = 8/302 (2%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P ++ +YV + +N +M++ +D+F QTW + RL+ I + L
Sbjct: 88 KPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTI-----KVLRLNSNMV 142
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD +F NSK + +T + ++ + V Y+ R+ CQ++ +PMD
Sbjct: 143 GKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEH 202
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
SCP+ S+ Y +++ ++W + V + Y + L T + G+Y
Sbjct: 203 SCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSF-VGLRNTTEVVKTTSGDYVV 261
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ VYF R++G+ IQT+ P +L+V+LSW SFW++ DA+P R T
Sbjct: 262 MSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 321
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVK--VLDKQYQMNKNKAQESMPRIIP 306
R +P V+YV A+DL+++ C +FVF+AL E+ + V +++ +K+K +++ I
Sbjct: 322 ARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTID 381
Query: 307 VR 308
+R
Sbjct: 382 IR 383
>BC069348-1|AAH69348.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor, gamma 2, isoform 2 precursor protein.
Length = 467
Score = 164 bits (398), Expect = 6e-40
Identities = 84/302 (27%), Positives = 153/302 (50%), Gaps = 8/302 (2%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P ++ +YV + +N +M++ +D+F QTW + RL+ I + L
Sbjct: 88 KPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTI-----KVLRLNSNMV 142
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD +F NSK + +T + ++ + V Y+ R+ CQ++ +PMD
Sbjct: 143 GKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEH 202
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
SCP+ S+ Y +++ ++W + V + Y + L T + G+Y
Sbjct: 203 SCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSF-VGLRNTTEVVKTTSGDYVV 261
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ VYF R++G+ IQT+ P +L+V+LSW SFW++ DA+P R T
Sbjct: 262 MSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 321
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVK--VLDKQYQMNKNKAQESMPRIIP 306
R +P V+YV A+DL+++ C +FVF+AL E+ + V +++ +K+K +++ I
Sbjct: 322 ARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTID 381
Query: 307 VR 308
+R
Sbjct: 382 IR 383
>BC059389-1|AAH59389.1| 475|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 2 protein.
Length = 475
Score = 164 bits (398), Expect = 6e-40
Identities = 81/288 (28%), Positives = 145/288 (50%), Gaps = 6/288 (2%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P ++ +YV + +N +M++ +D+F QTW + RL+ I + L
Sbjct: 88 KPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTI-----KVLRLNSNMV 142
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD +F NSK + +T + ++ + V Y+ R+ CQ++ +PMD
Sbjct: 143 GKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEH 202
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
SCP+ S+ Y +++ ++W + V + Y + L T + G+Y
Sbjct: 203 SCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSF-VGLRNTTEVVKTTSGDYVV 261
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ VYF R++G+ IQT+ P +L+V+LSW SFW++ DA+P R T
Sbjct: 262 MSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 321
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNK 296
R +P V+YV A+DL+++ C +FVF+AL E+ ++ + +K+K
Sbjct: 322 ARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLRYFVSNRKPSKDK 369
>AF269144-1|AAF99698.1| 467|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 467
Score = 164 bits (398), Expect = 6e-40
Identities = 82/275 (29%), Positives = 138/275 (50%), Gaps = 6/275 (2%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +++ IYV + ++ +M++++D+F QTW++SRL+ F +TL
Sbjct: 69 KPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLR-----FNSTMKILTLNSNMV 123
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD F NSK E +T + ++ + + Y+ R+ CQ++ +PMD
Sbjct: 124 GLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEH 183
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
SCP+ S+ Y +++ +RW + V + Y + L T + G+Y
Sbjct: 184 SCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDF-MGLRNTTEIVTTSAGDYVV 242
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ +YF R++G+ IQT+ P L V+LSW SFW+ DA P R T
Sbjct: 243 MTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTI 302
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
R +P V+YV A+DL++ C +FVFAAL E+ +
Sbjct: 303 ARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 337
Score = 32.3 bits (70), Expect = 3.3
Identities = 13/22 (59%), Positives = 15/22 (68%)
Query: 386 EIDKLSRVVFPALFLLFVTMYW 407
E+D SRV FP FLLF +YW
Sbjct: 440 ELDSYSRVFFPTSFLLFNLVYW 461
>AF228458-1|AAF63215.1| 449|Homo sapiens GABAA receptor gamma 3
subunit protein.
Length = 449
Score = 164 bits (398), Expect = 6e-40
Identities = 82/275 (29%), Positives = 138/275 (50%), Gaps = 6/275 (2%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +++ IYV + ++ +M++++D+F QTW++SRL+ F +TL
Sbjct: 51 KPTVIDVDIYVNSIGPVSSINMEYQIDIFFAQTWTDSRLR-----FNSTMKILTLNSNMV 105
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD F NSK E +T + ++ + + Y+ R+ CQ++ +PMD
Sbjct: 106 GLIWIPDTIFRNSKTAEAHWITTPNQLLRIWNDGKILYTLRLTINAECQLQLHNFPMDEH 165
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
SCP+ S+ Y +++ +RW + V + Y + L T + G+Y
Sbjct: 166 SCPLIFSSYGYPKEEMIYRWRKNSVEAADQKSWRLYQFDF-MGLRNTTEIVTTSAGDYVV 224
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ +YF R++G+ IQT+ P L V+LSW SFW+ DA P R T
Sbjct: 225 MTIYFELSRRMGYFTIQTYIPCILTVVLSWVSFWIKKDATPARTALGITTVLTMTTLSTI 284
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
R +P V+YV A+DL++ C +FVFAAL E+ +
Sbjct: 285 ARKSLPRVSYVTAMDLFVTVCFLFVFAALMEYATL 319
Score = 32.3 bits (70), Expect = 3.3
Identities = 13/22 (59%), Positives = 15/22 (68%)
Query: 386 EIDKLSRVVFPALFLLFVTMYW 407
E+D SRV FP FLLF +YW
Sbjct: 422 ELDSYSRVFFPTSFLLFNLVYW 443
>AF165124-1|AAD50273.1| 467|Homo sapiens gamma-aminobutyric acid A
receptor gamma 2 protein.
Length = 467
Score = 164 bits (398), Expect = 6e-40
Identities = 84/302 (27%), Positives = 153/302 (50%), Gaps = 8/302 (2%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P ++ +YV + +N +M++ +D+F QTW + RL+ I + L
Sbjct: 88 KPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFNSTI-----KVLRLNSNMV 142
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD +F NSK + +T + ++ + V Y+ R+ CQ++ +PMD
Sbjct: 143 GKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAECQLQLHNFPMDEH 202
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
SCP+ S+ Y +++ ++W + V + Y + L T + G+Y
Sbjct: 203 SCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSF-VGLRNTTEVVKTTSGDYVV 261
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ VYF R++G+ IQT+ P +L+V+LSW SFW++ DA+P R T
Sbjct: 262 MSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 321
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVK--VLDKQYQMNKNKAQESMPRIIP 306
R +P V+YV A+DL+++ C +FVF+AL E+ + V +++ +K+K +++ I
Sbjct: 322 ARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTID 381
Query: 307 VR 308
+R
Sbjct: 382 IR 383
>BC033801-1|AAH33801.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 163 bits (396), Expect = 1e-39
Identities = 89/302 (29%), Positives = 153/302 (50%), Gaps = 9/302 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G PV V ++ V ++ I+ +M++ + +F+ Q+W +SRL + ++ + L
Sbjct: 57 PGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLS-----YNHTNETLGL 111
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
F D LW PD + +N+K ++T + + L + + YS R+ + +AC M+ Y
Sbjct: 112 DSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKY 171
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMID 181
PMD Q C + +ES+ YS++ + + WSE+ I+ +L+L Q+ I E +
Sbjct: 172 PMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFK-- 229
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
G + RL ++F R G ++IQ++ PS L+V +SW SFW+ A+P R
Sbjct: 230 SAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLT 289
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESM 301
R+ +P + +KALD++ C +FVFAAL E+ + K K + S
Sbjct: 290 MTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSR 349
Query: 302 PR 303
PR
Sbjct: 350 PR 351
>AL391845-4|CAI15436.1| 452|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, delta protein.
Length = 452
Score = 163 bits (396), Expect = 1e-39
Identities = 89/302 (29%), Positives = 153/302 (50%), Gaps = 9/302 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G PV V ++ V ++ I+ +M++ + +F+ Q+W +SRL + ++ + L
Sbjct: 57 PGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLS-----YNHTNETLGL 111
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
F D LW PD + +N+K ++T + + L + + YS R+ + +AC M+ Y
Sbjct: 112 DSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKY 171
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMID 181
PMD Q C + +ES+ YS++ + + WSE+ I+ +L+L Q+ I E +
Sbjct: 172 PMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYRFTTELMNFK-- 229
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
G + RL ++F R G ++IQ++ PS L+V +SW SFW+ A+P R
Sbjct: 230 SAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLT 289
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESM 301
R+ +P + +KALD++ C +FVFAAL E+ + K K + S
Sbjct: 290 MTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSR 349
Query: 302 PR 303
PR
Sbjct: 350 PR 351
>X15376-1|CAA33437.1| 467|Homo sapiens GABA-A receptor gamma 2
subunit protein.
Length = 467
Score = 163 bits (395), Expect = 1e-39
Identities = 84/302 (27%), Positives = 152/302 (50%), Gaps = 8/302 (2%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P ++ +YV + +N +M++ +D+F Q W + RL+ I + L
Sbjct: 88 KPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQMWYDRRLKFNSTI-----KVLRLNSNMV 142
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD +F NSK + +T + ++ + V YS R+ CQ++ +PMD
Sbjct: 143 GKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYSLRLTIDAECQLQLHNFPMDEH 202
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
SCP+ S+ Y +++ ++W + V + Y + L T + G+Y
Sbjct: 203 SCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSF-VGLRNTTEVVKTTSGDYVV 261
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ VYF R++G+ IQT+ P +L+V+LSW SFW++ DA+P R T
Sbjct: 262 MSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGITTVLTMTTLSTI 321
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVK--VLDKQYQMNKNKAQESMPRIIP 306
R +P V+YV A+DL+++ C +FVF+AL E+ + V +++ +K+K +++ I
Sbjct: 322 ARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDKDKKKKNPAPTID 381
Query: 307 VR 308
+R
Sbjct: 382 IR 383
>AF016917-1|AAB70007.1| 452|Homo sapiens GABA-A receptor delta
subunit protein.
Length = 452
Score = 163 bits (395), Expect = 1e-39
Identities = 89/302 (29%), Positives = 153/302 (50%), Gaps = 9/302 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G PV V ++ V ++ I+ +M++ + +F+ Q+W +SRL + ++ + L
Sbjct: 57 PGIGGPPVNVALALEVASIDHISEANMEYTMTVFLHQSWRDSRLS-----YNHTNETLGL 111
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
F D LW PD + +N+K ++T + + L + + YS R+ + +AC M+ Y
Sbjct: 112 DSRFVDKLWLPDTFIVNAKSAWFHDVTVENKLIRLQPDGVILYSIRITSTVACDMDLAKY 171
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTIN--PELKLLQYHIGQPLRLEETNGYMID 181
PMD Q C + +ES+ YS++ + + WSE+ I+ +L+L Q+ I E +
Sbjct: 172 PMDEQECMLDLESYGYSSEDIVYYWSESQEHIHGLDKLQLAQFTITSYHFTTELMNFK-- 229
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
G + RL ++F R G ++IQ++ PS L+V +SW SFW+ A+P R
Sbjct: 230 SAGQFPRLSLHFHLRRNRGVYIIQSYMPSVLLVAMSWVSFWISQAAVPARVSLGITTVLT 289
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESM 301
R+ +P + +KALD++ C +FVFAAL E+ + K K + S
Sbjct: 290 MTTLMVSARSSLPRASAIKALDVYFWICYVFVFAALVEYAFAHFNADYRKKQKAKVKVSR 349
Query: 302 PR 303
PR
Sbjct: 350 PR 351
>Y07637-1|CAA68914.1| 505|Homo sapiens putative GABA-gated chloride
channel protein.
Length = 505
Score = 159 bits (385), Expect = 2e-38
Identities = 94/304 (30%), Positives = 146/304 (48%), Gaps = 16/304 (5%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +V I V + +++ DM++ +D+ QTW + RL D FE + L
Sbjct: 93 KPTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCY-NDTFES----LVLNGNVV 147
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
LW PD +F NSK T E+T V +Y++ V Y+ RM C + +PMD
Sbjct: 148 SQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSH 207
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPE--LKLLQYHIGQPLRLEETNGYMIDKDGNY 186
SCP+ SFSY ++ ++W + IN + KL Q+ E +I G++
Sbjct: 208 SCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDFTGVSNKTE----IITTPGDF 263
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
+ ++F R+ G+ Q + PSS+ MLSW SFW+ ++ P R
Sbjct: 264 MVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLG 323
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRIIP 306
T R + P V+Y+ ALD ++A C +F F AL EF V+ L N+ KA S P++
Sbjct: 324 TFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL----IYNQTKAHAS-PKLRH 378
Query: 307 VRLN 310
R+N
Sbjct: 379 PRIN 382
Score = 31.9 bits (69), Expect = 4.3
Identities = 13/25 (52%), Positives = 15/25 (60%)
Query: 387 IDKLSRVVFPALFLLFVTMYWPVLL 411
+D SRVVFP F F +YW V L
Sbjct: 479 LDNYSRVVFPVTFFFFNVLYWLVCL 503
>M86868-1|AAA52510.1| 465|Homo sapiens gamma-amino butyric acid
protein.
Length = 465
Score = 158 bits (383), Expect = 4e-38
Identities = 84/300 (28%), Positives = 148/300 (49%), Gaps = 6/300 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
PA G + V + V ++SI+ DMDF + +++R W + RL + +T
Sbjct: 70 PAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSS----ASNKSMTF 125
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F++SK + + T + ++ + V YS R+ C M+F +
Sbjct: 126 DGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHF 185
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL-LQYHIGQPLRLEETNGYMIDK 182
P+D Q+C + +ES++Y+++ + W ++ + K+ L + Q +
Sbjct: 186 PLDSQTCSLELESYAYTDEDLMLHWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFY-SS 244
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+RL + F R I L+QT+ P++L+VMLSW SFW+D A+P R
Sbjct: 245 TGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTM 304
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMP 302
TG+ A +P V+YVKA+D+++ +FVF ++ E+ V L + + K +E P
Sbjct: 305 TTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKFP 364
Score = 32.7 bits (71), Expect = 2.5
Identities = 12/23 (52%), Positives = 17/23 (73%)
Query: 387 IDKLSRVVFPALFLLFVTMYWPV 409
IDK SR++FPA ++ F +YW V
Sbjct: 441 IDKYSRLIFPASYIFFNLIYWSV 463
>M62400-1|AAA52509.1| 473|Homo sapiens gamma-aminobutyric acid
receptor type A rho-1 subunit protein.
Length = 473
Score = 158 bits (383), Expect = 4e-38
Identities = 85/300 (28%), Positives = 148/300 (49%), Gaps = 6/300 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G + V + V ++SI+ DMDF + +++R W + RL P + +T
Sbjct: 84 PGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPST----NNLSMTF 139
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F++SK + I + T + + + V YS R+ C M+F +
Sbjct: 140 DGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRF 199
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL-LQYHIGQPLRLEETNGYMIDK 182
P+D Q+C + IES++Y+ + W + ++ + ++ L + Q T
Sbjct: 200 PLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTT-TKLAFYSS 258
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+RL + F R I L+QT+ P++L+VMLSW SFW+D A+P R
Sbjct: 259 TGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTM 318
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMP 302
TG+ A +P V+Y+KA+D+++ +FVF ++ E+ V L + + K +E +P
Sbjct: 319 STIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLP 378
Score = 35.5 bits (78), Expect = 0.35
Identities = 13/29 (44%), Positives = 20/29 (68%)
Query: 381 RVLWREIDKLSRVVFPALFLLFVTMYWPV 409
R+ IDK SR++FPA ++LF +YW +
Sbjct: 443 RIDTHAIDKYSRIIFPAAYILFNLIYWSI 471
>BC130344-1|AAI30345.1| 474|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 474
Score = 158 bits (383), Expect = 4e-38
Identities = 85/300 (28%), Positives = 148/300 (49%), Gaps = 6/300 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G + V + V ++SI+ DMDF + +++R W + RL P + +T
Sbjct: 85 PGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPST----NNLSMTF 140
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F++SK + I + T + + + V YS R+ C M+F +
Sbjct: 141 DGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRF 200
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL-LQYHIGQPLRLEETNGYMIDK 182
P+D Q+C + IES++Y+ + W + ++ + ++ L + Q T
Sbjct: 201 PLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTT-TKLAFYSS 259
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+RL + F R I L+QT+ P++L+VMLSW SFW+D A+P R
Sbjct: 260 TGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTM 319
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMP 302
TG+ A +P V+Y+KA+D+++ +FVF ++ E+ V L + + K +E +P
Sbjct: 320 STIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLP 379
Score = 35.5 bits (78), Expect = 0.35
Identities = 13/29 (44%), Positives = 20/29 (68%)
Query: 381 RVLWREIDKLSRVVFPALFLLFVTMYWPV 409
R+ IDK SR++FPA ++LF +YW +
Sbjct: 444 RIDTHAIDKYSRIIFPAAYILFNLIYWSI 472
>AL353659-1|CAC36328.2| 473|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 473
Score = 158 bits (383), Expect = 4e-38
Identities = 85/300 (28%), Positives = 148/300 (49%), Gaps = 6/300 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G + V + V ++SI+ DMDF + +++R W + RL P + +T
Sbjct: 84 PGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPST----NNLSMTF 139
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F++SK + I + T + + + V YS R+ C M+F +
Sbjct: 140 DGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRF 199
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL-LQYHIGQPLRLEETNGYMIDK 182
P+D Q+C + IES++Y+ + W + ++ + ++ L + Q T
Sbjct: 200 PLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTT-TKLAFYSS 258
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+RL + F R I L+QT+ P++L+VMLSW SFW+D A+P R
Sbjct: 259 TGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTM 318
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMP 302
TG+ A +P V+Y+KA+D+++ +FVF ++ E+ V L + + K +E +P
Sbjct: 319 STIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLP 378
Score = 35.5 bits (78), Expect = 0.35
Identities = 13/29 (44%), Positives = 20/29 (68%)
Query: 381 RVLWREIDKLSRVVFPALFLLFVTMYWPV 409
R+ IDK SR++FPA ++LF +YW +
Sbjct: 443 RIDTHAIDKYSRIIFPAAYILFNLIYWSI 471
>AL353135-4|CAI16246.1| 473|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 1 protein.
Length = 473
Score = 158 bits (383), Expect = 4e-38
Identities = 85/300 (28%), Positives = 148/300 (49%), Gaps = 6/300 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G + V + V ++SI+ DMDF + +++R W + RL P + +T
Sbjct: 84 PGFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLSFPST----NNLSMTF 139
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F++SK + I + T + + + V YS R+ C M+F +
Sbjct: 140 DGRLVKKIWVPDMFFVHSKRSFIHDTTTDNVMLRVQPDGKVLYSLRVTVTAMCNMDFSRF 199
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL-LQYHIGQPLRLEETNGYMIDK 182
P+D Q+C + IES++Y+ + W + ++ + ++ L + Q T
Sbjct: 200 PLDTQTCSLEIESYAYTEDDLMLYWKKGNDSLKTDERISLSQFLIQEFHTT-TKLAFYSS 258
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+RL + F R I L+QT+ P++L+VMLSW SFW+D A+P R
Sbjct: 259 TGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVPLGITTVLTM 318
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMP 302
TG+ A +P V+Y+KA+D+++ +FVF ++ E+ V L + + K +E +P
Sbjct: 319 STIITGVNASMPRVSYIKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKEQKLREKLP 378
Score = 35.5 bits (78), Expect = 0.35
Identities = 13/29 (44%), Positives = 20/29 (68%)
Query: 381 RVLWREIDKLSRVVFPALFLLFVTMYWPV 409
R+ IDK SR++FPA ++LF +YW +
Sbjct: 443 RIDTHAIDKYSRIIFPAAYILFNLIYWSI 471
>BC130354-1|AAI30355.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 157 bits (381), Expect = 7e-38
Identities = 84/300 (28%), Positives = 148/300 (49%), Gaps = 6/300 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
PA G + V + V ++SI+ DMDF + +++R W + RL + +T
Sbjct: 70 PAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSS----ASNKSMTF 125
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F++SK + + T + ++ + V YS R+ C M+F +
Sbjct: 126 DGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHF 185
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL-LQYHIGQPLRLEETNGYMIDK 182
P+D Q+C + +ES++Y+++ + W ++ + K+ L + Q +
Sbjct: 186 PLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFY-SS 244
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+RL + F R I L+QT+ P++L+VMLSW SFW+D A+P R
Sbjct: 245 TGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTM 304
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMP 302
TG+ A +P V+YVKA+D+++ +FVF ++ E+ V L + + K +E P
Sbjct: 305 TTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKFP 364
Score = 32.7 bits (71), Expect = 2.5
Identities = 12/23 (52%), Positives = 17/23 (73%)
Query: 387 IDKLSRVVFPALFLLFVTMYWPV 409
IDK SR++FPA ++ F +YW V
Sbjct: 441 IDKYSRLIFPASYIFFNLIYWSV 463
>BC130352-1|AAI30353.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 157 bits (381), Expect = 7e-38
Identities = 84/300 (28%), Positives = 148/300 (49%), Gaps = 6/300 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
PA G + V + V ++SI+ DMDF + +++R W + RL + +T
Sbjct: 70 PAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSS----ASNKSMTF 125
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F++SK + + T + ++ + V YS R+ C M+F +
Sbjct: 126 DGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHF 185
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL-LQYHIGQPLRLEETNGYMIDK 182
P+D Q+C + +ES++Y+++ + W ++ + K+ L + Q +
Sbjct: 186 PLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFY-SS 244
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+RL + F R I L+QT+ P++L+VMLSW SFW+D A+P R
Sbjct: 245 TGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTM 304
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMP 302
TG+ A +P V+YVKA+D+++ +FVF ++ E+ V L + + K +E P
Sbjct: 305 TTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKFP 364
Score = 32.7 bits (71), Expect = 2.5
Identities = 12/23 (52%), Positives = 17/23 (73%)
Query: 387 IDKLSRVVFPALFLLFVTMYWPV 409
IDK SR++FPA ++ F +YW V
Sbjct: 441 IDKYSRLIFPASYIFFNLIYWSV 463
>AL121833-2|CAC07339.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) receptor, rho 2 protein.
Length = 465
Score = 157 bits (381), Expect = 7e-38
Identities = 84/300 (28%), Positives = 148/300 (49%), Gaps = 6/300 (2%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
PA G + V + V ++SI+ DMDF + +++R W + RL + +T
Sbjct: 70 PAFGGPAIPVGVDVQVESLDSISEVDMDFTMTLYLRHYWKDERLAFSS----ASNKSMTF 125
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F++SK + + T + ++ + V YS R+ C M+F +
Sbjct: 126 DGRLVKKIWVPDVFFVHSKRSFTHDTTTDNIMLRVFPDGHVLYSMRITVTAMCNMDFSHF 185
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKL-LQYHIGQPLRLEETNGYMIDK 182
P+D Q+C + +ES++Y+++ + W ++ + K+ L + Q +
Sbjct: 186 PLDSQTCSLELESYAYTDEDLMLYWKNGDESLKTDEKISLSQFLIQKFHTTSRLAFY-SS 244
Query: 183 DGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXX 242
G Y+RL + F R I L+QT+ P++L+VMLSW SFW+D A+P R
Sbjct: 245 TGWYNRLYINFTLRRHIFFFLLQTYFPATLMVMLSWVSFWIDRRAVPARVSLGITTVLTM 304
Query: 243 XXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMP 302
TG+ A +P V+YVKA+D+++ +FVF ++ E+ V L + + K +E P
Sbjct: 305 TTIITGVNASMPRVSYVKAVDIYLWVSFVFVFLSVLEYAAVNYLTTVQERKERKLREKFP 364
Score = 32.7 bits (71), Expect = 2.5
Identities = 12/23 (52%), Positives = 17/23 (73%)
Query: 387 IDKLSRVVFPALFLLFVTMYWPV 409
IDK SR++FPA ++ F +YW V
Sbjct: 441 IDKYSRLIFPASYIFFNLIYWSV 463
>Y09765-1|CAA70904.1| 506|Homo sapiens GABA receptor epsilon
subunit protein.
Length = 506
Score = 157 bits (380), Expect = 9e-38
Identities = 92/304 (30%), Positives = 145/304 (47%), Gaps = 15/304 (4%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +V I V + +++ DM++ +D+ QTW + RL D FE + L
Sbjct: 93 KPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLCY-NDTFES----LVLNGNVV 147
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
LW PD +F NSK T E+T V +Y++ V Y+ RM C + +PMD
Sbjct: 148 SQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSH 207
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPE--LKLLQYHIGQPLRLEETNGYMIDKDGNY 186
SCP+ SFSY ++ ++W + IN + KL Q+ + + G++
Sbjct: 208 SCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDF---TGVSNKTEIITTPVGDF 264
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
+ ++F R+ G+ Q + PSS+ MLSW SFW+ ++ P R
Sbjct: 265 MVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLG 324
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRIIP 306
T R + P V+Y+ ALD ++A C +F F AL EF V+ L N+ KA S P++
Sbjct: 325 TFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL----IYNQTKAHAS-PKLRH 379
Query: 307 VRLN 310
R+N
Sbjct: 380 PRIN 383
Score = 31.9 bits (69), Expect = 4.3
Identities = 13/25 (52%), Positives = 15/25 (60%)
Query: 387 IDKLSRVVFPALFLLFVTMYWPVLL 411
+D SRVVFP F F +YW V L
Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLVCL 504
>U92283-1|AAB94645.1| 506|Homo sapiens GABA-A receptor epsilon
subunit protein.
Length = 506
Score = 157 bits (380), Expect = 9e-38
Identities = 92/304 (30%), Positives = 145/304 (47%), Gaps = 15/304 (4%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +V I V + +++ DM++ +D+ QTW + RL D FE + L
Sbjct: 93 KPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLCY-NDTFES----LVLNGNVV 147
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
LW PD +F NSK T E+T V +Y++ V Y+ RM C + +PMD
Sbjct: 148 SQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSH 207
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPE--LKLLQYHIGQPLRLEETNGYMIDKDGNY 186
SCP+ SFSY ++ ++W + IN + KL Q+ + + G++
Sbjct: 208 SCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDF---TGVSNKTEIITTPVGDF 264
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
+ ++F R+ G+ Q + PSS+ MLSW SFW+ ++ P R
Sbjct: 265 MVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLG 324
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRIIP 306
T R + P V+Y+ ALD ++A C +F F AL EF V+ L N+ KA S P++
Sbjct: 325 TFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL----IYNQTKAHAS-PKLRH 379
Query: 307 VRLN 310
R+N
Sbjct: 380 PRIN 383
Score = 31.9 bits (69), Expect = 4.3
Identities = 13/25 (52%), Positives = 15/25 (60%)
Query: 387 IDKLSRVVFPALFLLFVTMYWPVLL 411
+D SRVVFP F F +YW V L
Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLVCL 504
>U66661-1|AAB49284.1| 506|Homo sapiens GABA-A receptor epsilon
subunit protein.
Length = 506
Score = 157 bits (380), Expect = 9e-38
Identities = 92/304 (30%), Positives = 145/304 (47%), Gaps = 15/304 (4%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +V I V + +++ DM++ +D+ QTW + RL D FE + L
Sbjct: 93 KPTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCY-NDTFES----LVLNGNVV 147
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
LW PD +F NSK T E+T V +Y++ V Y+ RM C + +PMD
Sbjct: 148 SQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSH 207
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPE--LKLLQYHIGQPLRLEETNGYMIDKDGNY 186
SCP+ SFSY ++ ++W + IN + KL Q+ + + G++
Sbjct: 208 SCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDF---TGVSNKTEIITTPVGDF 264
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
+ ++F R+ G+ Q + PSS+ MLSW SFW+ ++ P R
Sbjct: 265 MVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLG 324
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRIIP 306
T R + P V+Y+ ALD ++A C +F F AL EF V+ L N+ KA S P++
Sbjct: 325 TFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL----IYNQTKAHAS-PKLRH 379
Query: 307 VRLN 310
R+N
Sbjct: 380 PRIN 383
Score = 31.9 bits (69), Expect = 4.3
Identities = 13/25 (52%), Positives = 15/25 (60%)
Query: 387 IDKLSRVVFPALFLLFVTMYWPVLL 411
+D SRVVFP F F +YW V L
Sbjct: 480 LDNYSRVVFPVTFFFFNVLYWLVCL 504
>Y09763-1|CAA70903.1| 506|Homo sapiens GABRE protein.
Length = 506
Score = 155 bits (376), Expect = 3e-37
Identities = 90/302 (29%), Positives = 144/302 (47%), Gaps = 11/302 (3%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +V I V + +++ DM++ +D+ QTW + RL D FE + L
Sbjct: 93 KPTVVTVEISVNSLGPLSILDMEYTIDIIFSQTWYDERLCY-NDTFES----LVLNGNVV 147
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
LW PD +F NSK T E+T V +Y++ V Y+ RM C + +PMD
Sbjct: 148 SQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSH 207
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
SCP+ SFSY ++ ++W + IN + + + +T + G++
Sbjct: 208 SCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQLDFTGVSNKTE-IITTPVGDFMV 266
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ ++F R+ G+ Q + PSS+ MLSW SFW+ ++ P R T
Sbjct: 267 MTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLGTF 326
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESMPRIIPVR 308
R + P V+Y+ ALD ++A C +F F AL EF V+ L N+ KA S P++ R
Sbjct: 327 SRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL----IYNQTKAHAS-PKLRHPR 381
Query: 309 LN 310
+N
Sbjct: 382 IN 383
>BC059376-1|AAH59376.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 155 bits (376), Expect = 3e-37
Identities = 85/280 (30%), Positives = 134/280 (47%), Gaps = 10/280 (3%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +V I V + +++ DM++ +D+ QTW + RL D FE + L
Sbjct: 93 KPTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCY-NDTFES----LVLNGNVV 147
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
LW PD +F NSK T E+T V +Y++ V Y+ RM C + +PMD
Sbjct: 148 SQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSH 207
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPE--LKLLQYHIGQPLRLEETNGYMIDKDGNY 186
SCP+ SFSY ++ ++W + IN + KL Q+ + + G++
Sbjct: 208 SCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDF---TGVSNKTEIITTPVGDF 264
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
+ ++F R+ G+ Q + PSS+ MLSW SFW+ ++ P R
Sbjct: 265 MVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLG 324
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T R + P V+Y+ ALD ++A C +F F AL EF V+ L
Sbjct: 325 TFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
>BC047108-1|AAH47108.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 155 bits (376), Expect = 3e-37
Identities = 85/280 (30%), Positives = 134/280 (47%), Gaps = 10/280 (3%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +V I V + +++ DM++ +D+ QTW + RL D FE + L
Sbjct: 93 KPTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCY-NDTFES----LVLNGNVV 147
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
LW PD +F NSK T E+T V +Y++ V Y+ RM C + +PMD
Sbjct: 148 SQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSH 207
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPE--LKLLQYHIGQPLRLEETNGYMIDKDGNY 186
SCP+ SFSY ++ ++W + IN + KL Q+ + + G++
Sbjct: 208 SCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDF---TGVSNKTEIITTPVGDF 264
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
+ ++F R+ G+ Q + PSS+ MLSW SFW+ ++ P R
Sbjct: 265 MVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLG 324
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T R + P V+Y+ ALD ++A C +F F AL EF V+ L
Sbjct: 325 TFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
>BC026337-1|AAH26337.1| 365|Homo sapiens GABRE protein protein.
Length = 365
Score = 155 bits (376), Expect = 3e-37
Identities = 85/280 (30%), Positives = 134/280 (47%), Gaps = 10/280 (3%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P +V I V + +++ DM++ +D+ QTW + RL D FE + L
Sbjct: 93 KPTVVTVEIAVNSLGPLSILDMEYTIDIIFSQTWYDERLCY-NDTFES----LVLNGNVV 147
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
LW PD +F NSK T E+T V +Y++ V Y+ RM C + +PMD
Sbjct: 148 SQLWIPDTFFRNSKRTHEHEITMPNQMVRIYKDGKVLYTIRMTIDAGCSLHMLRFPMDSH 207
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTINPE--LKLLQYHIGQPLRLEETNGYMIDKDGNY 186
SCP+ SFSY ++ ++W + IN + KL Q+ + + G++
Sbjct: 208 SCPLSFSSFSYPENEMIYKWENFKLEINEKNSWKLFQFDF---TGVSNKTEIITTPVGDF 264
Query: 187 SRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXF 246
+ ++F R+ G+ Q + PSS+ MLSW SFW+ ++ P R
Sbjct: 265 MVMTIFFNVSRRFGYVAFQNYVPSSVTTMLSWVSFWIKTESAPARTSLGITSVLTMTTLG 324
Query: 247 TGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
T R + P V+Y+ ALD ++A C +F F AL EF V+ L
Sbjct: 325 TFSRKNFPRVSYITALDFYIAICFVFCFCALLEFAVLNFL 364
>BC031087-1|AAH31087.1| 465|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, gamma 1 protein.
Length = 465
Score = 153 bits (371), Expect = 1e-36
Identities = 78/273 (28%), Positives = 139/273 (50%), Gaps = 8/273 (2%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
+P ++E +YV + ++ +M++ +D+ QTW +SRL+ F + L
Sbjct: 86 RPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWFDSRLK-----FNSTMKVLMLNSNMV 140
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQ 128
+W PD +F NS+ ++ +T + ++ + V Y+ R+ C ++ +PMD
Sbjct: 141 GKIWIPDTFFRNSRKSDAHWITTPNRLLRIWNDGRVLYTLRLTINAECYLQLHNFPMDEH 200
Query: 129 SCPIYIESFSYSNQKVRFRWSEAGVTI-NPELKLLQYHIGQPLRLEETNGYMIDKDGNYS 187
SCP+ S+ Y ++ ++W + V + +P+ L LR + I G+Y
Sbjct: 201 SCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAFVGLRNSTEITHTIS--GDYV 258
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
+ ++F R++G+ IQT+ P L V+LSW SFW++ DA+P R T
Sbjct: 259 IMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVPARTSLGITTVLTMTTLST 318
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEF 280
R +P V+YV A+DL+++ C +FVFAAL E+
Sbjct: 319 IARKSLPKVSYVTAMDLFVSVCFIFVFAALMEY 351
>S81944-1|AAB36480.1| 453|Homo sapiens gamma-aminobutyric acid type
A receptor alpha 6 subunit protein.
Length = 453
Score = 147 bits (356), Expect = 7e-35
Identities = 89/310 (28%), Positives = 147/310 (47%), Gaps = 15/310 (4%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G V+ IYV ++ +M++ +D+F RQTW++ RL+ F + ++L
Sbjct: 49 PGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLK-----FGGPTEILSL 103
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F N K + +T + +N T+ Y+ R+ C M +
Sbjct: 104 NNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNF 163
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELK-LLQYH-IGQPLRLEETNGY 178
PMD +CP+ S++Y ++ + W + V + E LLQY IGQ + E
Sbjct: 164 PMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKS- 222
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
G Y + VYF +R++G+ +IQ + P + V+LS SFW++ +++P R
Sbjct: 223 ---NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITT 279
Query: 239 XXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL-DKQYQMNKNKA 297
R +P V+Y A+D ++A C FVF+AL EF V + Q Q K KA
Sbjct: 280 VLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKA 339
Query: 298 QESMPRIIPV 307
Q + P + +
Sbjct: 340 QFAAPPTVTI 349
>BC099641-1|AAH99641.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 147 bits (356), Expect = 7e-35
Identities = 89/310 (28%), Positives = 147/310 (47%), Gaps = 15/310 (4%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G V+ IYV ++ +M++ +D+F RQTW++ RL+ F + ++L
Sbjct: 49 PGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLK-----FGGPTEILSL 103
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F N K + +T + +N T+ Y+ R+ C M +
Sbjct: 104 NNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNF 163
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELK-LLQYH-IGQPLRLEETNGY 178
PMD +CP+ S++Y ++ + W + V + E LLQY IGQ + E
Sbjct: 164 PMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKS- 222
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
G Y + VYF +R++G+ +IQ + P + V+LS SFW++ +++P R
Sbjct: 223 ---NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITT 279
Query: 239 XXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL-DKQYQMNKNKA 297
R +P V+Y A+D ++A C FVF+AL EF V + Q Q K KA
Sbjct: 280 VLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKA 339
Query: 298 QESMPRIIPV 307
Q + P + +
Sbjct: 340 QFAAPPTVTI 349
>BC099640-1|AAH99640.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 147 bits (356), Expect = 7e-35
Identities = 89/310 (28%), Positives = 147/310 (47%), Gaps = 15/310 (4%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G V+ IYV ++ +M++ +D+F RQTW++ RL+ F + ++L
Sbjct: 49 PGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLK-----FGGPTEILSL 103
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F N K + +T + +N T+ Y+ R+ C M +
Sbjct: 104 NNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNF 163
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELK-LLQYH-IGQPLRLEETNGY 178
PMD +CP+ S++Y ++ + W + V + E LLQY IGQ + E
Sbjct: 164 PMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKS- 222
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
G Y + VYF +R++G+ +IQ + P + V+LS SFW++ +++P R
Sbjct: 223 ---NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITT 279
Query: 239 XXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL-DKQYQMNKNKA 297
R +P V+Y A+D ++A C FVF+AL EF V + Q Q K KA
Sbjct: 280 VLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKA 339
Query: 298 QESMPRIIPV 307
Q + P + +
Sbjct: 340 QFAAPPTVTI 349
>BC096242-1|AAH96242.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 147 bits (356), Expect = 7e-35
Identities = 89/310 (28%), Positives = 147/310 (47%), Gaps = 15/310 (4%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G V+ IYV ++ +M++ +D+F RQTW++ RL+ F + ++L
Sbjct: 49 PGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLK-----FGGPTEILSL 103
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F N K + +T + +N T+ Y+ R+ C M +
Sbjct: 104 NNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNF 163
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELK-LLQYH-IGQPLRLEETNGY 178
PMD +CP+ S++Y ++ + W + V + E LLQY IGQ + E
Sbjct: 164 PMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKS- 222
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
G Y + VYF +R++G+ +IQ + P + V+LS SFW++ +++P R
Sbjct: 223 ---NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITT 279
Query: 239 XXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL-DKQYQMNKNKA 297
R +P V+Y A+D ++A C FVF+AL EF V + Q Q K KA
Sbjct: 280 VLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKA 339
Query: 298 QESMPRIIPV 307
Q + P + +
Sbjct: 340 QFAAPPTVTI 349
>BC096241-1|AAH96241.1| 453|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 6 protein.
Length = 453
Score = 147 bits (356), Expect = 7e-35
Identities = 89/310 (28%), Positives = 147/310 (47%), Gaps = 15/310 (4%)
Query: 4 PARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTL 63
P G V+ IYV ++ +M++ +D+F RQTW++ RL+ F + ++L
Sbjct: 49 PGFGGAVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWTDERLK-----FGGPTEILSL 103
Query: 64 PPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLY 123
+W PD +F N K + +T + +N T+ Y+ R+ C M +
Sbjct: 104 NNLMVSKIWTPDTFFRNGKKSIAHNMTTPNKLFRIMQNGTILYTMRLTINADCPMRLVNF 163
Query: 124 PMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELK-LLQYH-IGQPLRLEETNGY 178
PMD +CP+ S++Y ++ + W + V + E LLQY IGQ + E
Sbjct: 164 PMDGHACPLKFGSYAYPKSEIIYTWKKGPLYSVEVPEESSSLLQYDLIGQTVSSETIKS- 222
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
G Y + VYF +R++G+ +IQ + P + V+LS SFW++ +++P R
Sbjct: 223 ---NTGEYVIMTVYFHLQRKMGYFMIQIYTPCIMTVILSQVSFWINKESVPARTVFGITT 279
Query: 239 XXXXXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL-DKQYQMNKNKA 297
R +P V+Y A+D ++A C FVF+AL EF V + Q Q K KA
Sbjct: 280 VLTMTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYFTNLQTQKAKRKA 339
Query: 298 QESMPRIIPV 307
Q + P + +
Sbjct: 340 QFAAPPTVTI 349
>U30461-1|AAB52519.1| 554|Homo sapiens GABAA receptor subunit
alpha4 protein.
Length = 554
Score = 146 bits (354), Expect = 1e-34
Identities = 91/301 (30%), Positives = 144/301 (47%), Gaps = 16/301 (5%)
Query: 8 GQPVI-VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPE 66
G PV V+ IYV ++ +M++ +D+F RQTW + RL+ I + + L
Sbjct: 68 GGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPI-----EILRLNNM 122
Query: 67 FFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMD 126
+W PD +F N K + +T + RN T+ Y+ R+ C M +PMD
Sbjct: 123 MVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMD 182
Query: 127 IQSCPIYIESFSYSNQKVRFRWS---EAGVTINPE-LKLLQYH-IGQPLRLEETNGYMID 181
+CP+ S++Y ++ + W+ E V + E L+QY IGQ + E
Sbjct: 183 GHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSI--- 239
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
G Y + VYF R++G+ +IQT+ P + V+LS SFW++ +++P R
Sbjct: 240 -TGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLT 298
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESM 301
R +P V+Y+ A+D ++A C FVF+AL EF V QM K K + S
Sbjct: 299 MTTLSISARHSLPKVSYLTAMDWFIAVCFAFVFSALIEFAAVNYF-TNIQMEKAKRKTSK 357
Query: 302 P 302
P
Sbjct: 358 P 358
Score = 31.1 bits (67), Expect = 7.6
Identities = 13/28 (46%), Positives = 18/28 (64%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLLLK 413
+IDK +R++FP F F +YW V L K
Sbjct: 517 KIDKYARILFPVTFGAFNMVYWVVYLSK 544
>L08485-1|AAA58490.1| 462|Homo sapiens GABA-benzodiazepine receptor
alpha-5-subunit protein.
Length = 462
Score = 146 bits (353), Expect = 2e-34
Identities = 85/294 (28%), Positives = 143/294 (48%), Gaps = 15/294 (5%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V IYV ++ +M++ +D+F RQ+W + RL+ F+ + L +W
Sbjct: 75 VRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLR-----FKGPMQRLPLNNLLASKIW 129
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + L + T+ Y+ R+ C M+ + +PMD +CP+
Sbjct: 130 TPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPL 189
Query: 133 YIESFSYSNQKVRFRWSEAG----VTINPELKLLQYHI-GQPLRLEETNGYMIDKDGNYS 187
S++Y N +V + W+ V +L QYH+ GQ + E + G Y+
Sbjct: 190 KFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENIS----TSTGEYT 245
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
+ +F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 246 IMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI 305
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ-YQMNKNKAQES 300
R +P VAY A+D ++A C FVF+AL EF V K+ + + KA E+
Sbjct: 306 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEA 359
Score = 34.3 bits (75), Expect = 0.81
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+IDK+SR+VFP LF F +YW L
Sbjct: 424 KIDKMSRIVFPVLFGTFNLVYWATYL 449
>BT009830-1|AAP88832.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 146 bits (353), Expect = 2e-34
Identities = 85/294 (28%), Positives = 143/294 (48%), Gaps = 15/294 (5%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V IYV ++ +M++ +D+F RQ+W + RL+ F+ + L +W
Sbjct: 75 VRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLR-----FKGPMQRLPLNNLLASKIW 129
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + L + T+ Y+ R+ C M+ + +PMD +CP+
Sbjct: 130 TPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPL 189
Query: 133 YIESFSYSNQKVRFRWSEAG----VTINPELKLLQYHI-GQPLRLEETNGYMIDKDGNYS 187
S++Y N +V + W+ V +L QYH+ GQ + E + G Y+
Sbjct: 190 KFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENIS----TSTGEYT 245
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
+ +F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 246 IMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI 305
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ-YQMNKNKAQES 300
R +P VAY A+D ++A C FVF+AL EF V K+ + + KA E+
Sbjct: 306 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEA 359
Score = 34.3 bits (75), Expect = 0.81
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+IDK+SR+VFP LF F +YW L
Sbjct: 424 KIDKMSRIVFPVLFGTFNLVYWATYL 449
>BC113422-1|AAI13423.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5 protein.
Length = 462
Score = 146 bits (353), Expect = 2e-34
Identities = 85/294 (28%), Positives = 143/294 (48%), Gaps = 15/294 (5%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V IYV ++ +M++ +D+F RQ+W + RL+ F+ + L +W
Sbjct: 75 VRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLR-----FKGPMQRLPLNNLLASKIW 129
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + L + T+ Y+ R+ C M+ + +PMD +CP+
Sbjct: 130 TPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPL 189
Query: 133 YIESFSYSNQKVRFRWSEAG----VTINPELKLLQYHI-GQPLRLEETNGYMIDKDGNYS 187
S++Y N +V + W+ V +L QYH+ GQ + E + G Y+
Sbjct: 190 KFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENIS----TSTGEYT 245
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
+ +F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 246 IMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI 305
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ-YQMNKNKAQES 300
R +P VAY A+D ++A C FVF+AL EF V K+ + + KA E+
Sbjct: 306 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEA 359
Score = 34.3 bits (75), Expect = 0.81
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+IDK+SR+VFP LF F +YW L
Sbjct: 424 KIDKMSRIVFPVLFGTFNLVYWATYL 449
>BC111979-1|AAI11980.1| 462|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 5, precursor protein.
Length = 462
Score = 146 bits (353), Expect = 2e-34
Identities = 85/294 (28%), Positives = 143/294 (48%), Gaps = 15/294 (5%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V IYV ++ +M++ +D+F RQ+W + RL+ F+ + L +W
Sbjct: 75 VRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLR-----FKGPMQRLPLNNLLASKIW 129
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + L + T+ Y+ R+ C M+ + +PMD +CP+
Sbjct: 130 TPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMRLTISAECPMQLEDFPMDAHACPL 189
Query: 133 YIESFSYSNQKVRFRWSEAG----VTINPELKLLQYHI-GQPLRLEETNGYMIDKDGNYS 187
S++Y N +V + W+ V +L QYH+ GQ + E + G Y+
Sbjct: 190 KFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQYHLMGQTVGTENIS----TSTGEYT 245
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
+ +F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 246 IMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI 305
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ-YQMNKNKAQES 300
R +P VAY A+D ++A C FVF+AL EF V K+ + + KA E+
Sbjct: 306 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEA 359
Score = 34.3 bits (75), Expect = 0.81
Identities = 14/26 (53%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+IDK+SR+VFP LF F +YW L
Sbjct: 424 KIDKMSRIVFPVLFGTFNLVYWATYL 449
>BC035055-1|AAH35055.1| 554|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 4 protein.
Length = 554
Score = 146 bits (353), Expect = 2e-34
Identities = 91/301 (30%), Positives = 143/301 (47%), Gaps = 16/301 (5%)
Query: 8 GQPVI-VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPE 66
G PV V+ IYV ++ +M++ +D+F RQTW + RL+ I + + L
Sbjct: 68 GGPVTEVKTDIYVTSFGPVSDVEMEYTMDVFFRQTWIDKRLKYDGPI-----EILRLNNM 122
Query: 67 FFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMD 126
+W PD +F N K + +T + RN T+ Y+ R+ C M +PMD
Sbjct: 123 MVTKVWTPDTFFRNGKKSVSHNMTAPNKLFRIMRNGTILYTMRLTISAECPMRLVDFPMD 182
Query: 127 IQSCPIYIESFSYSNQKVRFRWS---EAGVTINPE-LKLLQYH-IGQPLRLEETNGYMID 181
+CP+ S++Y ++ + W+ E V + E L+QY IGQ + E
Sbjct: 183 GHACPLKFGSYAYPKSEMIYTWTKGPEKSVEVPKESSSLVQYDLIGQTVSSETIKSI--- 239
Query: 182 KDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXX 241
G Y + VYF R++G+ +IQT+ P + V+LS SFW++ +++P R
Sbjct: 240 -TGEYIVMTVYFHLRRKMGYFMIQTYIPCIMTVILSQVSFWINKESVPARTVFGITTVLT 298
Query: 242 XXXXFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQMNKNKAQESM 301
R +P V+Y A+D ++A C FVF+AL EF V QM K K + S
Sbjct: 299 MTTLSISARHSLPKVSYATAMDWFIAVCFAFVFSALIEFAAVNYF-TNIQMEKAKRKTSK 357
Query: 302 P 302
P
Sbjct: 358 P 358
Score = 31.1 bits (67), Expect = 7.6
Identities = 13/28 (46%), Positives = 18/28 (64%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLLLK 413
+IDK +R++FP F F +YW V L K
Sbjct: 517 KIDKYARILFPVTFGAFNMVYWVVYLSK 544
>BC022488-1|AAH22488.1| 367|Homo sapiens GABRA2 protein protein.
Length = 367
Score = 142 bits (343), Expect = 3e-33
Identities = 81/279 (29%), Positives = 137/279 (49%), Gaps = 14/279 (5%)
Query: 16 SIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPD 75
+IYV ++ DM++ +D+F RQ W + RL+ F+ + + L +W PD
Sbjct: 71 NIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLK-----FKGPMNILRLNNLMASKIWTPD 125
Query: 76 PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIE 135
+F N K + +T + + + T+ Y+ R+ C M + +PMD SCP+
Sbjct: 126 TFFHNGKKSAAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFG 185
Query: 136 SFSYSNQKVRFRWS---EAGVTINPE-LKLLQYHI-GQPLRLEETNGYMIDKDGNYSRLV 190
S++Y+ +V + W+ V + P+ +L QY + GQ + E G Y+ +
Sbjct: 186 SYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKS----STGEYTVMT 241
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
+F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R R
Sbjct: 242 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 301
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
+P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 302 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
>S62908-1|AAB27279.1| 492|Homo sapiens gamma-aminobutyric acidA
receptor alpha 3 subunit protein.
Length = 492
Score = 141 bits (342), Expect = 4e-33
Identities = 82/279 (29%), Positives = 135/279 (48%), Gaps = 8/279 (2%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V+ IYV ++ DM++ +D+F RQTW + RL+ F+ + L +W
Sbjct: 93 VKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLK-----FDGPMKILPLNNLLASKIW 147
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + L N T+ Y+ R+ C M + +PMD+ +CP+
Sbjct: 148 TPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPL 207
Query: 133 YIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD--GNYSRLV 190
S++Y+ +V + W+ G + E+ + Q L G I + G Y +
Sbjct: 208 KFGSYAYTTAEVVYSWT-LGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMT 266
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
+F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R R
Sbjct: 267 THFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 326
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
+P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 327 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365
Score = 35.5 bits (78), Expect = 0.35
Identities = 12/31 (38%), Positives = 21/31 (67%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLLLKTKA 416
++DK+SR++FP LF +F +YW + + A
Sbjct: 454 KVDKISRIIFPVLFAIFNLVYWATYVNRESA 484
>S62907-1|AAB27278.1| 451|Homo sapiens gamma-aminobutyric acidA
receptor alpha 2 subunit protein.
Length = 451
Score = 141 bits (342), Expect = 4e-33
Identities = 81/279 (29%), Positives = 137/279 (49%), Gaps = 14/279 (5%)
Query: 16 SIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPD 75
+IYV ++ DM++ +D+F RQ W + RL+ F+ + + L +W PD
Sbjct: 71 NIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLK-----FKGPMNILRLNNLMASKIWTPD 125
Query: 76 PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIE 135
+F N K + +T + + + T+ Y+ R+ C M + +PMD SCP+
Sbjct: 126 TFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFG 185
Query: 136 SFSYSNQKVRFRWS---EAGVTINPE-LKLLQYHI-GQPLRLEETNGYMIDKDGNYSRLV 190
S++Y+ +V + W+ V + P+ +L QY + GQ + E G Y+ +
Sbjct: 186 SYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKS----STGEYTVMT 241
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
+F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R R
Sbjct: 242 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 301
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
+P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 302 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Score = 33.1 bits (72), Expect = 1.9
Identities = 13/26 (50%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+ID++SR+VFP LF F +YW L
Sbjct: 416 KIDRMSRIVFPVLFGTFNLVYWATYL 441
>BC028629-1|AAH28629.1| 492|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 3 protein.
Length = 492
Score = 141 bits (342), Expect = 4e-33
Identities = 82/279 (29%), Positives = 135/279 (48%), Gaps = 8/279 (2%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V+ IYV ++ DM++ +D+F RQTW + RL+ F+ + L +W
Sbjct: 93 VKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLK-----FDGPMKILPLNNLLASKIW 147
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + L N T+ Y+ R+ C M + +PMD+ +CP+
Sbjct: 148 TPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLPYTMRLTIHAECPMHLEDFPMDVHACPL 207
Query: 133 YIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD--GNYSRLV 190
S++Y+ +V + W+ G + E+ + Q L G I + G Y +
Sbjct: 208 KFGSYAYTTAEVVYSWT-LGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMT 266
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
+F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R R
Sbjct: 267 THFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 326
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
+P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 327 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365
Score = 35.5 bits (78), Expect = 0.35
Identities = 12/31 (38%), Positives = 21/31 (67%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLLLKTKA 416
++DK+SR++FP LF +F +YW + + A
Sbjct: 454 KVDKISRIIFPVLFAIFNLVYWATYVNRESA 484
>AF166361-1|AAG12455.1| 492|Homo sapiens GABA receptor subunit
alpha 3 protein.
Length = 492
Score = 141 bits (342), Expect = 4e-33
Identities = 82/279 (29%), Positives = 135/279 (48%), Gaps = 8/279 (2%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V+ IYV ++ DM++ +D+F RQTW + RL+ F+ + L +W
Sbjct: 93 VKTDIYVTSFGPVSDTDMEYTIDVFFRQTWHDERLK-----FDGPMKILPLNNLLASKIW 147
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + L N T+ Y+ R+ C M + +PMD+ +CP+
Sbjct: 148 TPDTFFHNGKKSVAHNMTTPNKLLRLVDNGTLLYTMRLTIHAECPMHLEDFPMDVHACPL 207
Query: 133 YIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKD--GNYSRLV 190
S++Y+ +V + W+ G + E+ + Q L G I + G Y +
Sbjct: 208 KFGSYAYTTAEVVYSWT-LGKNKSVEVAQDGSRLNQYDLLGHVVGTEIIRSSTGEYVVMT 266
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
+F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R R
Sbjct: 267 THFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 326
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
+P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 327 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 365
Score = 35.5 bits (78), Expect = 0.35
Identities = 12/31 (38%), Positives = 21/31 (67%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLLLKTKA 416
++DK+SR++FP LF +F +YW + + A
Sbjct: 454 KVDKISRIIFPVLFAIFNLVYWATYVNRESA 484
>AB209295-1|BAD92532.1| 461|Homo sapiens gamma-aminobutyric acid A
receptor, alpha 2 precursor variant protein.
Length = 461
Score = 141 bits (342), Expect = 4e-33
Identities = 81/279 (29%), Positives = 137/279 (49%), Gaps = 14/279 (5%)
Query: 16 SIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPD 75
+IYV ++ DM++ +D+F RQ W + RL+ F+ + + L +W PD
Sbjct: 81 NIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLK-----FKGPMNILRLNNLMASKIWTPD 135
Query: 76 PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIE 135
+F N K + +T + + + T+ Y+ R+ C M + +PMD SCP+
Sbjct: 136 TFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFG 195
Query: 136 SFSYSNQKVRFRWS---EAGVTINPE-LKLLQYHI-GQPLRLEETNGYMIDKDGNYSRLV 190
S++Y+ +V + W+ V + P+ +L QY + GQ + E G Y+ +
Sbjct: 196 SYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIKS----STGEYTVMT 251
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLR 250
+F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R R
Sbjct: 252 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISAR 311
Query: 251 ADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
+P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 312 NSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 350
Score = 33.1 bits (72), Expect = 1.9
Identities = 13/26 (50%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+ID++SR+VFP LF F +YW L
Sbjct: 426 KIDRMSRIVFPVLFGTFNLVYWATYL 451
>BC030696-1|AAH30696.1| 456|Homo sapiens GABRA1 protein protein.
Length = 456
Score = 138 bits (335), Expect = 3e-32
Identities = 79/282 (28%), Positives = 137/282 (48%), Gaps = 14/282 (4%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V+ I+V ++ DM++ +D+F RQ+W + RL+ F+ + L +W
Sbjct: 68 VKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLK-----FKGPMTVLRLNNLMASKIW 122
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + + + T+ Y+ R+ C M + +PMD +CP+
Sbjct: 123 TPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPL 182
Query: 133 YIESFSYSNQKVRFRWSE----AGVTINPELKLLQYHI-GQPLRLEETNGYMIDKDGNYS 187
S++Y+ +V + W+ + V +L QY + GQ + +G + G Y
Sbjct: 183 KFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTV----DSGIVQSSTGEYV 238
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
+ +F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 239 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI 298
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
R +P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 299 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Score = 33.1 bits (72), Expect = 1.9
Identities = 13/26 (50%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+ID+LSR+ FP LF +F +YW L
Sbjct: 418 KIDRLSRIAFPLLFGIFNLVYWATYL 443
>AK223447-1|BAD97167.1| 456|Homo sapiens gamma-aminobutyric acid
(GABA) A receptor, alpha 1 precursor variant protein.
Length = 456
Score = 138 bits (335), Expect = 3e-32
Identities = 79/282 (28%), Positives = 137/282 (48%), Gaps = 14/282 (4%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V+ I+V ++ DM++ +D+F RQ+W + RL+ F+ + L +W
Sbjct: 68 VKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLK-----FKGPMTVLRLNNLMASKIW 122
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + + + T+ Y+ R+ C M + +PMD +CP+
Sbjct: 123 TPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPL 182
Query: 133 YIESFSYSNQKVRFRWSE----AGVTINPELKLLQYHI-GQPLRLEETNGYMIDKDGNYS 187
S++Y+ +V + W+ + V +L QY + GQ + +G + G Y
Sbjct: 183 KFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTV----DSGIVQSSTGEYV 238
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
+ +F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 239 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI 298
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
R +P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 299 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Score = 33.1 bits (72), Expect = 1.9
Identities = 13/26 (50%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+ID+LSR+ FP LF +F +YW L
Sbjct: 418 KIDRLSRIAFPLLFGIFNLVYWATYL 443
>X14766-1|CAA32874.1| 456|Homo sapiens GABA-A receptor alpha 1
subunit protein.
Length = 456
Score = 133 bits (321), Expect = 1e-30
Identities = 78/282 (27%), Positives = 136/282 (48%), Gaps = 14/282 (4%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V+ I+V ++ DM++ +D+F RQ+W + RL+ F+ + L +
Sbjct: 68 VKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLK-----FKGPMTVLRLNNLMASKIR 122
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD +F N K + +T + + + T+ Y+ R+ C M + +PMD +CP+
Sbjct: 123 TPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPL 182
Query: 133 YIESFSYSNQKVRFRWSE----AGVTINPELKLLQYHI-GQPLRLEETNGYMIDKDGNYS 187
S++Y+ +V + W+ + V +L QY + GQ + +G + G Y
Sbjct: 183 KFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQYDLLGQTV----DSGIVQSSTGEYV 238
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
+ +F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 239 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI 298
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ 289
R +P VAY A+D ++A C FVF+AL EF V K+
Sbjct: 299 SARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKR 340
Score = 33.1 bits (72), Expect = 1.9
Identities = 13/26 (50%), Positives = 18/26 (69%)
Query: 386 EIDKLSRVVFPALFLLFVTMYWPVLL 411
+ID+LSR+ FP LF +F +YW L
Sbjct: 418 KIDRLSRIAFPLLFGIFNLVYWATYL 443
>X13584-1|CAA31925.1| 354|Homo sapiens protein ( Human mRNA for
gamma-aminobutyric-acid receptor alpha-subunit (GABA-A
receptor alpha-subunit). ).
Length = 354
Score = 120 bits (290), Expect = 7e-27
Identities = 80/284 (28%), Positives = 135/284 (47%), Gaps = 29/284 (10%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V+ I+V ++ DM++ +D+F RQ+W + RL+ F+ + L +W
Sbjct: 68 VKTDIFVTSFGPVSDHDMEYTIDVFFRQSWKDERLK-----FKGPMTVLRLNNLMASKIW 122
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPI 132
PD F+ +K+ I E + T+ Y+ R+ C M + +PMD +CP+
Sbjct: 123 TPDT-FMPNKLLRITE------------DGTLLYTMRLTVRAECPMHLEDFPMDAHACPL 169
Query: 133 YIESFSYSNQKVRFRWSE----AGVTINPELKLLQYHI-GQPLRLEETNGYMIDKDGNYS 187
S++Y+ +V + W+ + V +L QY + GQ + +G + G Y
Sbjct: 170 KFGSYAYTRAEVVYEWTREPAHSVVVAEDGSRLNQYDLLGQTV----DSGIVQSSTGEYV 225
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
+ +F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 226 VMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSI 285
Query: 248 GLRADIPPVAYVKALDL-W-MAGCMMFVFAALGEFVVVKVLDKQ 289
R +P VAY A+D W +A C FVF+AL EF V K+
Sbjct: 286 SARNSLPKVAYATAMDWDWFIAVCYAFVFSALIEFATVNYFTKR 329
>AC093745-1|AAY40994.1| 222|Homo sapiens unknown protein.
Length = 222
Score = 112 bits (269), Expect = 3e-24
Identities = 63/221 (28%), Positives = 113/221 (51%), Gaps = 14/221 (6%)
Query: 16 SIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPD 75
+IYV ++ DM++ +D+F RQ W + RL+ F+ + + L +W PD
Sbjct: 8 NIYVTSFGPVSDTDMEYTIDVFFRQKWKDERLK-----FKGPMNILRLNNLMASKIWTPD 62
Query: 76 PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQSCPIYIE 135
+F N K + +T + + + T+ Y+ R+ C M + +PMD SCP+
Sbjct: 63 TFFHNGKKSVAHNMTMPNKLLRIQDDGTLLYTMRLTVQAECPMHLEDFPMDAHSCPLKFG 122
Query: 136 SFSYSNQKVRFRW---SEAGVTINPE-LKLLQYH-IGQPLRLEETNGYMIDKDGNYSRLV 190
S++Y+ +V + W + V + P+ +L QY +GQ + E G Y+ +
Sbjct: 123 SYAYTTSEVTYIWTYNASDSVQVAPDGSRLNQYDLLGQSIGKETIK----SSTGEYTVMT 178
Query: 191 VYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGR 231
+F +R+IG+ +IQT+ P + V+LS SFWL+ +++P R
Sbjct: 179 AHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPAR 219
>AF018157-1|AAC39918.1| 219|Homo sapiens glycine receptor alpha 3
subunit protein.
Length = 219
Score = 105 bits (252), Expect = 3e-22
Identities = 44/99 (44%), Positives = 66/99 (66%)
Query: 193 FRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGLRAD 252
F ERQ+G++LIQ + PS L+V+LSW SFW+++DA P R +G RA
Sbjct: 2 FHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVALGITTVLTMTTQSSGSRAS 61
Query: 253 IPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQYQ 291
+P V+YVKA+D+WMA C++FVF+AL E+ V + +Q++
Sbjct: 62 LPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQHK 100
>AC131948-1|AAY40916.1| 74|Homo sapiens unknown protein.
Length = 74
Score = 56.8 bits (131), Expect = 1e-07
Identities = 27/77 (35%), Positives = 42/77 (54%), Gaps = 4/77 (5%)
Query: 31 DFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLWHPDPYFLNSKVTEIAELT 90
D+RV++F+RQ W++ RL E DD + L P D++W PD +F N K E+T
Sbjct: 1 DYRVNIFLRQKWNDPRLAYSE----YPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVT 56
Query: 91 HKFSSVTLYRNQTVRYS 107
+ +++N V YS
Sbjct: 57 TDNKLLRIFKNGNVLYS 73
>X14830-1|CAA32939.1| 501|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor beta-subunit. ).
Length = 501
Score = 54.8 bits (126), Expect = 5e-07
Identities = 52/238 (21%), Positives = 103/238 (43%), Gaps = 17/238 (7%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP G V V + + + S+N +D + +++ W++ RL + +G D
Sbjct: 42 VRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSW-DPAEHDGIDS 100
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ + E ++W PD LN+ SV + + +VR+ +C ++
Sbjct: 101 LRITAE---SVWLPDVVLLNNNDGNFDVALD--ISVVVSSDGSVRWQPPGIYRSSCSIQV 155
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFR---------WSEAGVTINPELKLLQY-HIGQPL 170
+P D Q+C + S+SY + +V + E + ++ Q+ +I +P
Sbjct: 156 TYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQWENIHKPS 215
Query: 171 RLEETNG-YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
RL + G ++G ++ Y R+ +L+ AP L+ +L+ F F+L DA
Sbjct: 216 RLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDA 273
>BC023553-1|AAH23553.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 54.4 bits (125), Expect = 7e-07
Identities = 52/238 (21%), Positives = 102/238 (42%), Gaps = 17/238 (7%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP G V V + + + S+N +D + +++ W++ RL + +G D
Sbjct: 42 VRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSW-DPAEHDGIDS 100
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ + E ++W PD LN+ SV + + +VR+ +C ++
Sbjct: 101 LRITAE---SVWLPDVVLLNNNDGNFYVALD--ISVVVSSDGSVRWQPPGIYRSSCSIQV 155
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFR---------WSEAGVTINPELKLLQYH-IGQPL 170
+P D Q+C + S+SY + +V + E + ++ Q+ I +P
Sbjct: 156 TYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQWEIIHKPS 215
Query: 171 RLEETNG-YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
RL + G ++G ++ Y R+ +L+ AP L+ +L+ F F+L DA
Sbjct: 216 RLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDA 273
>BC011371-1|AAH11371.1| 501|Homo sapiens cholinergic receptor,
nicotinic, beta 1 (muscle) protein.
Length = 501
Score = 54.4 bits (125), Expect = 7e-07
Identities = 52/238 (21%), Positives = 102/238 (42%), Gaps = 17/238 (7%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP G V V + + + S+N +D + +++ W++ RL + +G D
Sbjct: 42 VRPAREVGDRVRVSVGLILAQLISLNEKDEEMSTKVYLDLEWTDYRLSW-DPAEHDGIDS 100
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ + E ++W PD LN+ SV + + +VR+ +C ++
Sbjct: 101 LRITAE---SVWLPDVVLLNNNDGNFDVALD--ISVVVSSDGSVRWQPPGIYRSSCSIQV 155
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFR---------WSEAGVTINPELKLLQYH-IGQPL 170
+P D Q+C + S+SY + +V + E + ++ Q+ I +P
Sbjct: 156 TYFPFDWQNCTMVFSSYSYDSSEVSLQTGLGPDGQGHQEIHIHEGTFIENGQWEIIHKPS 215
Query: 171 RLEETNG-YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
RL + G ++G ++ Y R+ +L+ AP L+ +L+ F F+L DA
Sbjct: 216 RLIQPPGDPRGGREGQRQEVIFYLIIRRKPLFYLVNVIAPCILITLLAIFVFYLPPDA 273
>M86383-1|AAC84176.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha 3 subunit precursor protein.
Length = 502
Score = 52.4 bits (120), Expect = 3e-06
Identities = 46/231 (19%), Positives = 97/231 (41%), Gaps = 17/231 (7%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ + G +
Sbjct: 47 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSGY-GGAEF 105
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P + +W PD N+ V + ++T K ++ Y + + +C+++
Sbjct: 106 MRVPAQ---KIWKPDIVLYNNAVGDF-QVTTKTKALLKYTGEVTWIPPAIFK-SSCKIDV 160
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMI 180
+P D Q+C + S+SY K+ V I + L Y + + GY
Sbjct: 161 TYFPFDYQNCTMKFGSWSYDKAKIDL------VLIGSSMNLKDYWESGEWAIIKAPGYKH 214
Query: 181 DKDGNYSRL----VVYFRFERQIG-HHLIQTFAPSSLVVMLSWFSFWLDLD 226
D N + Y + R++ + I P L+ L+ F+L D
Sbjct: 215 DIKYNCCEEIYPDITYSLYSRRLPLFYTINLIIPCLLISFLTVLVFYLPSD 265
>BC101183-1|AAI01184.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 52.4 bits (120), Expect = 3e-06
Identities = 44/216 (20%), Positives = 87/216 (40%), Gaps = 7/216 (3%)
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
NLW PD + + ++ ++ + T K + + +RY M C ++ +P D Q+
Sbjct: 134 NLWLPDIFII--ELMDV-DKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQN 190
Query: 130 CPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN-YS 187
C + SF Y+ + E + +LQ H L + + GN Y
Sbjct: 191 CTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQTHGEWELLGLSKATAKLSRGGNLYD 250
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
++V Y R+ ++I PS +V + SF+L + + G F
Sbjct: 251 QIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPVKS--GNRVPFKITLLLGYNVFL 308
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ +D+ P + + ++ A C+ + +L E + +
Sbjct: 309 LMMSDLLPTSGTPLIGVYFALCLSLMVGSLLETIFI 344
>BC101182-1|AAI01183.1| 471|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member E protein.
Length = 471
Score = 52.4 bits (120), Expect = 3e-06
Identities = 44/216 (20%), Positives = 87/216 (40%), Gaps = 7/216 (3%)
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
NLW PD + + ++ ++ + T K + + +RY M C ++ +P D Q+
Sbjct: 134 NLWLPDIFII--ELMDV-DKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQN 190
Query: 130 CPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN-YS 187
C + SF Y+ + E + +LQ H L + + GN Y
Sbjct: 191 CTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQTHGEWELLGLSKATAKLSRGGNLYD 250
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
++V Y R+ ++I PS +V + SF+L + + G F
Sbjct: 251 QIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPVKS--GNRVPFKITLLLGYNVFL 308
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ +D+ P + + ++ A C+ + +L E + +
Sbjct: 309 LMMSDLLPTSGTPLIGVYFALCLSLMVGSLLETIFI 344
>AY349353-1|AAQ93477.1| 456|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 456
Score = 52.4 bits (120), Expect = 3e-06
Identities = 44/216 (20%), Positives = 87/216 (40%), Gaps = 7/216 (3%)
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
NLW PD + + ++ ++ + T K + + +RY M C ++ +P D Q+
Sbjct: 119 NLWLPDIFII--ELMDV-DKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQN 175
Query: 130 CPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN-YS 187
C + SF Y+ + E + +LQ H L + + GN Y
Sbjct: 176 CTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQTHGEWELLGLSKATAKLSRGGNLYD 235
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
++V Y R+ ++I PS +V + SF+L + + G F
Sbjct: 236 QIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPVKS--GNRVPFKITLLLGYNVFL 293
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ +D+ P + + ++ A C+ + +L E + +
Sbjct: 294 LMMSDLLPTSGTPLIGVYFALCLSLMVGSLLETIFI 329
>AY349352-1|AAQ93476.1| 441|Homo sapiens 5-HT3c1 serotonin
receptor-like protein protein.
Length = 441
Score = 52.4 bits (120), Expect = 3e-06
Identities = 44/216 (20%), Positives = 87/216 (40%), Gaps = 7/216 (3%)
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
NLW PD + + ++ ++ + T K + + +RY M C ++ +P D Q+
Sbjct: 104 NLWLPDIFII--ELMDV-DKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQN 160
Query: 130 CPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN-YS 187
C + SF Y+ + E + +LQ H L + + GN Y
Sbjct: 161 CTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQTHGEWELLGLSKATAKLSRGGNLYD 220
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
++V Y R+ ++I PS +V + SF+L + + G F
Sbjct: 221 QIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPVKS--GNRVPFKITLLLGYNVFL 278
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ +D+ P + + ++ A C+ + +L E + +
Sbjct: 279 LMMSDLLPTSGTPLIGVYFALCLSLMVGSLLETIFI 314
>AY159813-1|AAO38167.2| 471|Homo sapiens 5-hydroxytryptamine
serotonin receptor 3E protein.
Length = 471
Score = 52.4 bits (120), Expect = 3e-06
Identities = 44/216 (20%), Positives = 87/216 (40%), Gaps = 7/216 (3%)
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
NLW PD + + ++ ++ + T K + + +RY M C ++ +P D Q+
Sbjct: 134 NLWLPDIFII--ELMDV-DKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQN 190
Query: 130 CPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGN-YS 187
C + SF Y+ + E + +LQ H L + + GN Y
Sbjct: 191 CTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQTHGEWELLGLSKATAKLSRGGNLYD 250
Query: 188 RLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFT 247
++V Y R+ ++I PS +V + SF+L + + G F
Sbjct: 251 QIVFYVAIRRRPSLYVINLLVPSGFLVAIDALSFYLPVKS--GNRVPFKITLLLGYNVFL 308
Query: 248 GLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ +D+ P + + ++ A C+ + +L E + +
Sbjct: 309 LMMSDLLPTSGTPLIGVYFALCLSLMVGSLLETIFI 344
>Y08418-1|CAA69695.1| 503|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 503
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 48 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 105
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 106 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 161 VTYFPFDYQNCTMKFGSWSYDKAKI 185
>X53559-1|CAA37625.1| 474|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-3merase protein.
Length = 474
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 19 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 76
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 77 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 131
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 132 VTYFPFDYQNCTMKFGSWSYDKAKI 156
>U62432-1|AAB40110.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha3 subunit precursor protein.
Length = 504
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 49 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 106
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 107 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 161
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 162 VTYFPFDYQNCTMKFGSWSYDKAKI 186
>M37981-1|AAA59942.1| 503|Homo sapiens neuronal nicotinic
acetylcholine receptor protein.
Length = 503
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 48 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 105
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 106 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 161 VTYFPFDYQNCTMKFGSWSYDKAKI 185
>BT006897-1|AAP35543.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 505
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 50 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 107
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 108 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 162
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 163 VTYFPFDYQNCTMKFGSWSYDKAKI 187
>BT006646-1|AAP35292.1| 489|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 3 protein.
Length = 489
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 50 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 107
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 108 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 162
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 163 VTYFPFDYQNCTMKFGSWSYDKAKI 187
>BC098443-1|AAH98443.1| 504|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 504
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 49 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 106
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 107 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 161
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 162 VTYFPFDYQNCTMKFGSWSYDKAKI 186
>BC006114-1|AAH06114.1| 489|Homo sapiens CHRNA3 protein protein.
Length = 489
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 50 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 107
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 108 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 162
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 163 VTYFPFDYQNCTMKFGSWSYDKAKI 187
>BC002996-1|AAH02996.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 50 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 107
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 108 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 162
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 163 VTYFPFDYQNCTMKFGSWSYDKAKI 187
>BC001642-1|AAH01642.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 50 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 107
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 108 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 162
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 163 VTYFPFDYQNCTMKFGSWSYDKAKI 187
>BC000513-1|AAH00513.1| 505|Homo sapiens cholinergic receptor,
nicotinic, alpha 3 protein.
Length = 505
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 50 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 107
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 108 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 162
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 163 VTYFPFDYQNCTMKFGSWSYDKAKI 187
>AJ007783-1|CAA07682.1| 504|Homo sapiens nicotinic acetylcholine
receptor alpha-3 subunit protein.
Length = 504
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 49 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 106
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 107 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 161
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 162 VTYFPFDYQNCTMKFGSWSYDKAKI 186
>AF385584-1|AAK68110.1| 489|Homo sapiens nicotinic cholinergic
receptor alpha 3 protein.
Length = 489
Score = 50.8 bits (116), Expect = 9e-06
Identities = 30/145 (20%), Positives = 69/145 (47%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP A PVI+ F + + + ++ + +++++Q W++ +L+ P D G +
Sbjct: 44 IRPVANVSDPVIIHFEVSMSQLVKVDEVNQIMETNLWLKQIWNDYKLKWNPSDY--GGAE 101
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P + +W PD N+ V + ++ K ++ Y + + +C+++
Sbjct: 102 FMRVPAQ---KIWKPDIVLYNNAVGDF-QVDDKTKALLKYTGEVTWIPPAIFK-SSCKID 156
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S+SY K+
Sbjct: 157 VTYFPFDYQNCTMKFGSWSYDKAKI 181
>Y16282-1|CAA76155.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 49.6 bits (113), Expect = 2e-05
Identities = 28/144 (19%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP PV V F + + + +++ + ++++R W++ +L+ + + +G +
Sbjct: 49 IRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRW-DPMEYDGIET 107
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N+ V + ++ K ++ Y N + ++ +C M+
Sbjct: 108 LRVPA---DKIWKPDIVLYNNAVGDF-QVEGKTKALLKY-NGMITWTPPAIFKSSCPMDI 162
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y ++
Sbjct: 163 TFFPFDHQNCSLKFGSWTYDKAEI 186
>Y08421-1|CAA69698.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP A V+V F + + + ++ ++ +++++Q W + +L+ P D E
Sbjct: 53 RPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADY--ENVTS 110
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ + A +TH + L+ + V+++ +C ++
Sbjct: 111 IRIPSEL---IWRPDIVLYNNADGDFA-VTH-LTKAHLFHDGRVQWTPPAIYKSSCSIDV 165
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y K+
Sbjct: 166 TFFPFDQQNCTMKFGSWTYDKAKI 189
>X89741-1|CAA61893.1| 627|Homo sapiens neuronal acetylcholine
receptor alpha-4 subunit protein.
Length = 627
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP A V+V F + + + ++ ++ +++++Q W + +L+ P D E
Sbjct: 53 RPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADY--ENVTS 110
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ + A +TH + L+ + V+++ +C ++
Sbjct: 111 IRIPSEL---IWRPDIVLYNNADGDFA-VTH-LTKAHLFHDGRVQWTPPAIYKSSCSIDV 165
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y K+
Sbjct: 166 TFFPFDQQNCTMKFGSWTYDKAKI 189
>X87629-1|CAA60959.1| 602|Homo sapiens nicotinic acetylcholine
receptor protein.
Length = 602
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP A V+V F + + + ++ ++ +++++Q W + +L+ P D E
Sbjct: 28 RPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADY--ENVTS 85
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ + A +TH + L+ + V+++ +C ++
Sbjct: 86 IRIPSEL---IWRPDIVLYNNADGDFA-VTH-LTKAHLFHDGRVQWTPPAIYKSSCSIDV 140
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y K+
Sbjct: 141 TFFPFDQQNCTMKFGSWTYDKAKI 164
>U62435-1|AAB40113.1| 494|Homo sapiens nicotinic acetylcholine
receptor alpha6 subunit precursor protein.
Length = 494
Score = 49.6 bits (113), Expect = 2e-05
Identities = 28/144 (19%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP PV V F + + + +++ + ++++R W++ +L+ + + +G +
Sbjct: 49 IRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRW-DPMEYDGIET 107
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N+ V + ++ K ++ Y N + ++ +C M+
Sbjct: 108 LRVPA---DKIWKPDIVLYNNAVGDF-QVEGKTKALLKY-NGMITWTPPAIFKSSCPMDI 162
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y ++
Sbjct: 163 TFFPFDHQNCSLKFGSWTYDKAEI 186
>U62433-1|AAB40111.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha4 subunit precursor protein.
Length = 627
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP A V+V F + + + ++ ++ +++++Q W + +L+ P D E
Sbjct: 53 RPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADY--ENVTS 110
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ + A +TH + L+ + V+++ +C ++
Sbjct: 111 IRIPSEL---IWRPDIVLYNNADGDFA-VTH-LTKAHLFHDGRVQWTPPAIYKSSCSIDV 165
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y K+
Sbjct: 166 TFFPFDQQNCTMKFGSWTYDKAKI 189
>L35901-1|AAA64743.1| 627|Homo sapiens nicotinic acetylcholine
receptor alpha 4 subunit protein.
Length = 627
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP A V+V F + + + ++ ++ +++++Q W + +L+ P D E
Sbjct: 53 RPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADY--ENVTS 110
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ + A +TH + L+ + V+++ +C ++
Sbjct: 111 IRIPSEL---IWRPDIVLYNNADGDFA-VTH-LTKAHLFHDGRVQWTPPAIYKSSCSIDV 165
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y K+
Sbjct: 166 TFFPFDQQNCTMKFGSWTYDKAKI 189
>DQ093071-1|AAY88737.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 4 protein.
Length = 627
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP A V+V F + + + ++ ++ +++++Q W + +L+ P D E
Sbjct: 53 RPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADY--ENVTS 110
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ + A +TH + L+ + V+++ +C ++
Sbjct: 111 IRIPSEL---IWRPDIVLYNNADGDFA-VTH-LTKAHLFHDGRVQWTPPAIYKSSCSIDV 165
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y K+
Sbjct: 166 TFFPFDQQNCTMKFGSWTYDKAKI 189
>BC096290-1|AAH96290.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP A V+V F + + + ++ ++ +++++Q W + +L+ P D E
Sbjct: 53 RPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADY--ENVTS 110
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ + A +TH + L+ + V+++ +C ++
Sbjct: 111 IRIPSEL---IWRPDIVLYNNADGDFA-VTH-LTKAHLFHDGRVQWTPPAIYKSSCSIDV 165
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y K+
Sbjct: 166 TFFPFDQQNCTMKFGSWTYDKAKI 189
>BC014456-1|AAH14456.1| 494|Homo sapiens cholinergic receptor,
nicotinic, alpha 6 protein.
Length = 494
Score = 49.6 bits (113), Expect = 2e-05
Identities = 28/144 (19%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP PV V F + + + +++ + ++++R W++ +L+ + + +G +
Sbjct: 49 IRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRW-DPMEYDGIET 107
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N+ V + ++ K ++ Y N + ++ +C M+
Sbjct: 108 LRVPA---DKIWKPDIVLYNNAVGDF-QVEGKTKALLKY-NGMITWTPPAIFKSSCPMDI 162
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y ++
Sbjct: 163 TFFPFDHQNCSLKFGSWTYDKAEI 186
>AL121827-20|CAC36119.1| 627|Homo sapiens cholinergic receptor,
nicotinic, alpha 4 protein.
Length = 627
Score = 49.6 bits (113), Expect = 2e-05
Identities = 31/144 (21%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP A V+V F + + + ++ ++ +++++Q W + +L+ P D E
Sbjct: 53 RPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDPADY--ENVTS 110
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ + A +TH + L+ + V+++ +C ++
Sbjct: 111 IRIPSEL---IWRPDIVLYNNADGDFA-VTH-LTKAHLFHDGRVQWTPPAIYKSSCSIDV 165
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y K+
Sbjct: 166 TFFPFDQQNCTMKFGSWTYDKAKI 189
>AB079251-1|BAC06855.1| 494|Homo sapiens Nicotinic acetylcholine
receptor alpha 6 protein.
Length = 494
Score = 49.6 bits (113), Expect = 2e-05
Identities = 28/144 (19%), Positives = 69/144 (47%), Gaps = 6/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP PV V F + + + +++ + ++++R W++ +L+ + + +G +
Sbjct: 49 IRPVENVSDPVTVHFEVAITQLANVDEVNQIMETNLWLRHIWNDYKLRW-DPMEYDGIET 107
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N+ V + ++ K ++ Y N + ++ +C M+
Sbjct: 108 LRVPA---DKIWKPDIVLYNNAVGDF-QVEGKTKALLKY-NGMITWTPPAIFKSSCPMDI 162
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y ++
Sbjct: 163 TFFPFDHQNCSLKFGSWTYDKAEI 186
>Z23141-1|CAA80672.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha polypeptide 7 protein.
Length = 479
Score = 48.8 bits (111), Expect = 4e-05
Identities = 66/294 (22%), Positives = 116/294 (39%), Gaps = 23/294 (7%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A QP+ V FS+ ++ + ++ ++ +++++ +W++ LQ + G V
Sbjct: 19 RPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEY-PGVKTV 77
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P +W PD NS H ++V + + +Y +C ++ +
Sbjct: 78 RFPD---GQIWKPDILLYNSADERFDATFH--TNVLVNSSGHCQYLPPGIFKSSCYIDVR 132
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELKLLQYHIGQPLRLEETNGY 178
+P D+Q C + S+SY + + EA G N E L +G P + E Y
Sbjct: 133 WFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDL----VGIPGKRSE-RFY 187
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
K+ Y + R+ ++ + P L+ L+ F L D+ G
Sbjct: 188 ECCKE-PYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADS--GEKISLGIT 244
Query: 239 XXXXXXXFTGLRADIPPVA--YVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY 290
F L A+I P V + + A M+ V G VVV V+ QY
Sbjct: 245 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIV----GLSVVVTVIVLQY 294
>Y08420-1|CAA69697.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 48.8 bits (111), Expect = 4e-05
Identities = 66/294 (22%), Positives = 116/294 (39%), Gaps = 23/294 (7%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A QP+ V FS+ ++ + ++ ++ +++++ +W++ LQ + G V
Sbjct: 42 RPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEY-PGVKTV 100
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P +W PD NS H ++V + + +Y +C ++ +
Sbjct: 101 RFPD---GQIWKPDILLYNSADERFDATFH--TNVLVNSSGHCQYLPPGIFKSSCYIDVR 155
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELKLLQYHIGQPLRLEETNGY 178
+P D+Q C + S+SY + + EA G N E L +G P + E Y
Sbjct: 156 WFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDL----VGIPGKRSE-RFY 210
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
K+ Y + R+ ++ + P L+ L+ F L D+ G
Sbjct: 211 ECCKE-PYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADS--GEKISLGIT 267
Query: 239 XXXXXXXFTGLRADIPPVA--YVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY 290
F L A+I P V + + A M+ V G VVV V+ QY
Sbjct: 268 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIV----GLSVVVTVIVLQY 317
>X70297-1|CAA49778.1| 502|Homo sapiens neuronal nicotinic
acetylocholine receptor alpha-7 subunit protein.
Length = 502
Score = 48.8 bits (111), Expect = 4e-05
Identities = 66/294 (22%), Positives = 116/294 (39%), Gaps = 23/294 (7%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A QP+ V FS+ ++ + ++ ++ +++++ +W++ LQ + G V
Sbjct: 42 RPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEY-PGVKTV 100
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P +W PD NS H ++V + + +Y +C ++ +
Sbjct: 101 RFPD---GQIWKPDILLYNSADERFDATFH--TNVLVNSSGHCQYLPPGIFKSSCYIDVR 155
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELKLLQYHIGQPLRLEETNGY 178
+P D+Q C + S+SY + + EA G N E L +G P + E Y
Sbjct: 156 WFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDL----VGIPGKRSE-RFY 210
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
K+ Y + R+ ++ + P L+ L+ F L D+ G
Sbjct: 211 ECCKE-PYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADS--GEKISLGIT 267
Query: 239 XXXXXXXFTGLRADIPPVA--YVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY 290
F L A+I P V + + A M+ V G VVV V+ QY
Sbjct: 268 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIV----GLSVVVTVIVLQY 317
>U62436-1|AAB40114.1| 502|Homo sapiens nicotinic acetylcholine
receptor alpha7 subunit precursor protein.
Length = 502
Score = 48.8 bits (111), Expect = 4e-05
Identities = 66/294 (22%), Positives = 116/294 (39%), Gaps = 23/294 (7%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A QP+ V FS+ ++ + ++ ++ +++++ +W++ LQ + G V
Sbjct: 42 RPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEY-PGVKTV 100
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P +W PD NS H ++V + + +Y +C ++ +
Sbjct: 101 RFPD---GQIWKPDILLYNSADERFDATFH--TNVLVNSSGHCQYLPPGIFKSSCYIDVR 155
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELKLLQYHIGQPLRLEETNGY 178
+P D+Q C + S+SY + + EA G N E L +G P + E Y
Sbjct: 156 WFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDL----VGIPGKRSE-RFY 210
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
K+ Y + R+ ++ + P L+ L+ F L D+ G
Sbjct: 211 ECCKE-PYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADS--GEKISLGIT 267
Query: 239 XXXXXXXFTGLRADIPPVA--YVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY 290
F L A+I P V + + A M+ V G VVV V+ QY
Sbjct: 268 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIV----GLSVVVTVIVLQY 317
>AJ586911-1|CAE52911.1| 502|Homo sapiens nicotinic acetylcholine
alpha-7 subunit protein.
Length = 502
Score = 48.8 bits (111), Expect = 4e-05
Identities = 66/294 (22%), Positives = 116/294 (39%), Gaps = 23/294 (7%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A QP+ V FS+ ++ + ++ ++ +++++ +W++ LQ + G V
Sbjct: 42 RPVANDSQPLTVYFSLSLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEY-PGVKTV 100
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P +W PD NS H ++V + + +Y +C ++ +
Sbjct: 101 RFPD---GQIWKPDILLYNSADERFDATFH--TNVLVNSSGHCQYLPPGIFKSSCYIDVR 155
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELKLLQYHIGQPLRLEETNGY 178
+P D+Q C + S+SY + + EA G N E L +G P + E Y
Sbjct: 156 WFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDL----VGIPGKRSE-RFY 210
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
K+ Y + R+ ++ + P L+ L+ F L D+ G
Sbjct: 211 ECCKE-PYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADS--GEKISLGIT 267
Query: 239 XXXXXXXFTGLRADIPPVA--YVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY 290
F L A+I P V + + A M+ V G VVV V+ QY
Sbjct: 268 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIV----GLSVVVTVIVLQY 317
>AF459285-1|AAL66182.1| 447|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit C protein.
Length = 447
Score = 48.8 bits (111), Expect = 4e-05
Identities = 44/222 (19%), Positives = 88/222 (39%), Gaps = 11/222 (4%)
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQT--VRYSARMHAIIACQMEFQLYPMD 126
+NLW PD + + E ++ S +T Y + ++Y M C+++ +P D
Sbjct: 118 ENLWLPDIF-----IVESMDVDQTPSGLTAYISSEGRIKYDKPMRVTSICKLDIFYFPFD 172
Query: 127 IQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYH-IGQPLRLEETNGYMIDKDG 184
Q+C SF Y+ + E + K++Q + L + + M +
Sbjct: 173 QQNCTFTFSSFLYTVDSMLLGMDKEVWEITDTSRKVIQTQGEWELLGINKATPKMSMGNN 232
Query: 185 NYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXX 244
Y +++ Y R+ ++I PSS +V + SF+L ++
Sbjct: 233 LYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPAES--ENRAPFKITLLLGYN 290
Query: 245 XFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
F + D+ P + + ++ A C+ + +L E V + L
Sbjct: 291 VFLLMMNDLLPASGTPLISVYFALCLSLMVVSLLETVFITYL 332
>U40583-1|AAA83561.1| 502|Homo sapiens alpha 7 neuronal nicotinic
acetylcholine receptor protein.
Length = 502
Score = 48.4 bits (110), Expect = 5e-05
Identities = 66/294 (22%), Positives = 116/294 (39%), Gaps = 23/294 (7%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A QP+ V FS+ ++ + ++ ++ +++++ +W++ LQ + G V
Sbjct: 42 RPVANDSQPLTVYFSLNLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEY-PGVKTV 100
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P +W PD NS H ++V + + +Y +C ++ +
Sbjct: 101 RFPD---GQIWKPDILLYNSADERFDATFH--TNVLVNPSGHCQYLPPGIFKSSCYIDVR 155
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELKLLQYHIGQPLRLEETNGY 178
+P D+Q C + S+SY + + EA G N E L +G P + E Y
Sbjct: 156 WFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDL----VGIPGKRSE-RFY 210
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
K+ Y + R+ ++ + P L+ L+ F L D+ G
Sbjct: 211 ECCKE-PYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADS--GEKISLGIT 267
Query: 239 XXXXXXXFTGLRADIPPVA--YVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY 290
F L A+I P V + + A M+ V G VVV V+ QY
Sbjct: 268 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIV----GLSVVVTVIVLQY 317
>BC131799-1|AAI31800.1| 447|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3, family member C protein.
Length = 447
Score = 48.4 bits (110), Expect = 5e-05
Identities = 44/222 (19%), Positives = 87/222 (39%), Gaps = 11/222 (4%)
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQT--VRYSARMHAIIACQMEFQLYPMD 126
+NLW PD + + E ++ S +T Y + ++Y M C ++ +P D
Sbjct: 118 ENLWLPDIF-----IVESMDVDQTPSGLTAYISSEGRIKYDKPMRVTSICNLDIFYFPFD 172
Query: 127 IQSCPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYH-IGQPLRLEETNGYMIDKDG 184
Q+C SF Y+ + E + K++Q + L + + M +
Sbjct: 173 QQNCTFTFSSFLYTVDSMLLGMDKEVWEITDTSRKVIQTQGEWELLGINKATPKMSMGNN 232
Query: 185 NYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXX 244
Y +++ Y R+ ++I PSS +V + SF+L ++
Sbjct: 233 LYDQIMFYVAIRRRPSLYIINLLVPSSFLVAIDALSFYLPAES--ENRAPFKITLLLGYN 290
Query: 245 XFTGLRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVL 286
F + D+ P + + ++ A C+ + +L E V + L
Sbjct: 291 VFLLMMNDLLPASGTPLISVYFALCLSLMVVSLLETVFITYL 332
>AF385585-1|AAK68111.1| 502|Homo sapiens nicotinic cholinergic
receptor alpha 7 protein.
Length = 502
Score = 48.4 bits (110), Expect = 5e-05
Identities = 66/294 (22%), Positives = 116/294 (39%), Gaps = 23/294 (7%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP A QP+ V FS+ ++ + ++ ++ +++++ +W++ LQ + G V
Sbjct: 42 RPVANDSQPLTVYFSLNLLQIMDVDEKNQVLTTNIWLQMSWTDHYLQWNVSEY-PGVKTV 100
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
P +W PD NS H ++V + + +Y +C ++ +
Sbjct: 101 RFPD---GQIWKPDILLYNSADERFDATFH--TNVLVNPSGHCQYLPPGIFKSSCYIDVR 155
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWSEA---GVTINPELKLLQYHIGQPLRLEETNGY 178
+P D+Q C + S+SY + + EA G N E L +G P + E Y
Sbjct: 156 WFPFDVQHCKLKFGSWSYGGWSLDLQMQEADISGYIPNGEWDL----VGIPGKRSE-RFY 210
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
K+ Y + R+ ++ + P L+ L+ F L D+ G
Sbjct: 211 ECCKE-PYPDVTFTVTMRRRTLYYGLNLLIPCVLISALALLVFLLPADS--GEKISLGIT 267
Query: 239 XXXXXXXFTGLRADIPPVA--YVKALDLWMAGCMMFVFAALGEFVVVKVLDKQY 290
F L A+I P V + + A M+ V G VVV V+ QY
Sbjct: 268 VLLSLTVFMLLVAEIMPATSDSVPLIAQYFASTMIIV----GLSVVVTVIVLQY 317
>Y16281-1|CAA76154.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 48.0 bits (109), Expect = 6e-05
Identities = 35/155 (22%), Positives = 68/155 (43%), Gaps = 8/155 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP VIV F + + + ++ ++ +++++Q WS+ +L+ P D
Sbjct: 75 RPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADF--GNITS 132
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ E A +TH + L+ TV + +C ++
Sbjct: 133 LRVPSEM---IWIPDIVLYNNADGEFA-VTH-MTKAHLFSTGTVHWVPPAIYKSSCSIDV 187
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTI 155
+P D Q+C + S++Y K+ E V +
Sbjct: 188 TFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDL 222
>U62431-1|AAB40109.1| 529|Homo sapiens nicotinic acetylcholine
receptor alpha2 subunit precursor protein.
Length = 529
Score = 48.0 bits (109), Expect = 6e-05
Identities = 35/155 (22%), Positives = 68/155 (43%), Gaps = 8/155 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDDH 60
RP VIV F + + + ++ ++ +++++Q WS+ +L+ P D
Sbjct: 75 RPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPADF--GNITS 132
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P E +W PD N+ E A +TH + L+ TV + +C ++
Sbjct: 133 LRVPSEM---IWIPDIVLYNNADGEFA-VTH-MTKAHLFSTGTVHWVPPAIYKSSCSIDV 187
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTI 155
+P D Q+C + S++Y K+ E V +
Sbjct: 188 TFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDL 222
>S82612-1|AAB37533.2| 478|Homo sapiens 5-hydroxytryptamine type 3AS
receptor subunit protein.
Length = 478
Score = 47.6 bits (108), Expect = 8e-05
Identities = 50/295 (16%), Positives = 120/295 (40%), Gaps = 16/295 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 49 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 103
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L +++ ++ + + V + V+ + + AC ++
Sbjct: 104 NITKLSIPTDSIWVPD--ILINELVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNG 177
+P D+Q+C + S+ ++ Q + + + + L L
Sbjct: 161 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 220
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
+ ++ Y+ + Y R+ +++ PS ++++ F+L ++ G
Sbjct: 221 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS--GERVSFKI 278
Query: 238 XXXXXXXXFTGLRADIPPVAYV--KALDLWMAGCMMFVFAALGEFV-VVKVLDKQ 289
F + +D P + + ++ CM + +L E + +V+++ KQ
Sbjct: 279 TLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLTETIFIVRLVHKQ 333
>D49394-1|BAA08387.1| 478|Homo sapiens serotonin 5-HT3 receptor
protein.
Length = 478
Score = 47.6 bits (108), Expect = 8e-05
Identities = 50/295 (16%), Positives = 119/295 (40%), Gaps = 16/295 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 49 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 103
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L ++ ++ + + V + V+ + + AC ++
Sbjct: 104 NITKLSIPTDSIWVPD--ILINEFVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNG 177
+P D+Q+C + S+ ++ Q + + + + L L
Sbjct: 161 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 220
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
+ ++ Y+ + Y R+ +++ PS ++++ F+L ++ G
Sbjct: 221 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS--GERVSFKI 278
Query: 238 XXXXXXXXFTGLRADIPPVAYV--KALDLWMAGCMMFVFAALGEFV-VVKVLDKQ 289
F + +D P + + ++ CM + +L E + +V+++ KQ
Sbjct: 279 TLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 333
>BT007204-1|AAP35868.1| 484|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 484
Score = 47.6 bits (108), Expect = 8e-05
Identities = 50/295 (16%), Positives = 119/295 (40%), Gaps = 16/295 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 55 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 109
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L ++ ++ + + V + V+ + + AC ++
Sbjct: 110 NITKLSIPTDSIWVPD--ILINEFVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 166
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNG 177
+P D+Q+C + S+ ++ Q + + + + L L
Sbjct: 167 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 226
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
+ ++ Y+ + Y R+ +++ PS ++++ F+L ++ G
Sbjct: 227 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS--GERVSFKI 284
Query: 238 XXXXXXXXFTGLRADIPPVAYV--KALDLWMAGCMMFVFAALGEFV-VVKVLDKQ 289
F + +D P + + ++ CM + +L E + +V+++ KQ
Sbjct: 285 TLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 339
>BC004453-1|AAH04453.2| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 47.6 bits (108), Expect = 8e-05
Identities = 50/295 (16%), Positives = 119/295 (40%), Gaps = 16/295 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 49 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 103
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L ++ ++ + + V + V+ + + AC ++
Sbjct: 104 NITKLSIPTDSIWVPD--ILINEFVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNG 177
+P D+Q+C + S+ ++ Q + + + + L L
Sbjct: 161 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 220
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
+ ++ Y+ + Y R+ +++ PS ++++ F+L ++ G
Sbjct: 221 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS--GERVSFKI 278
Query: 238 XXXXXXXXFTGLRADIPPVAYV--KALDLWMAGCMMFVFAALGEFV-VVKVLDKQ 289
F + +D P + + ++ CM + +L E + +V+++ KQ
Sbjct: 279 TLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 333
>BC002354-1|AAH02354.1| 478|Homo sapiens 5-hydroxytryptamine
(serotonin) receptor 3A protein.
Length = 478
Score = 47.6 bits (108), Expect = 8e-05
Identities = 50/295 (16%), Positives = 119/295 (40%), Gaps = 16/295 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 49 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 103
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L ++ ++ + + V + V+ + + AC ++
Sbjct: 104 NITKLSIPTDSIWVPD--ILINEFVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNG 177
+P D+Q+C + S+ ++ Q + + + + L L
Sbjct: 161 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 220
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
+ ++ Y+ + Y R+ +++ PS ++++ F+L ++ G
Sbjct: 221 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS--GERVSFKI 278
Query: 238 XXXXXXXXFTGLRADIPPVAYV--KALDLWMAGCMMFVFAALGEFV-VVKVLDKQ 289
F + +D P + + ++ CM + +L E + +V+++ KQ
Sbjct: 279 TLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 333
>AJ306454-1|CAC34819.1| 497|Homo sapiens neuronal nicotinic
acetylcholine receptor beta-4 subunit protein.
Length = 497
Score = 47.6 bits (108), Expect = 8e-05
Identities = 28/144 (19%), Positives = 70/144 (48%), Gaps = 7/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q + ++ + + + S+N + +++++Q W++ RL +E G +
Sbjct: 44 IRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYE-GVNI 102
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P + +W PD N+ T + ++++ + N +V + AC++E
Sbjct: 103 LRIPAK---RIWLPDIVLYNNDGTYEVSV---YTNLIVRSNGSVLWLPPAIYKSACKIEV 156
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+ +P D Q+C + S++Y + ++
Sbjct: 157 KYFPFDQQNCTLKFRSWTYDHTEI 180
>AJ005205-1|CAA06442.3| 478|Homo sapiens serotonin 3 receptor
protein.
Length = 478
Score = 47.6 bits (108), Expect = 8e-05
Identities = 50/295 (16%), Positives = 119/295 (40%), Gaps = 16/295 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 49 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 103
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L ++ ++ + + V + V+ + + AC ++
Sbjct: 104 NITKLSIPTDSIWVPD--ILINEFVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNG 177
+P D+Q+C + S+ ++ Q + + + + L L
Sbjct: 161 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 220
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
+ ++ Y+ + Y R+ +++ PS ++++ F+L ++ G
Sbjct: 221 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS--GERVSFKI 278
Query: 238 XXXXXXXXFTGLRADIPPVAYV--KALDLWMAGCMMFVFAALGEFV-VVKVLDKQ 289
F + +D P + + ++ CM + +L E + +V+++ KQ
Sbjct: 279 TLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 333
>AJ003079-1|CAA05852.1| 478|Homo sapiens 5-hydroxytryptamine3
receptor protein.
Length = 478
Score = 47.6 bits (108), Expect = 8e-05
Identities = 50/295 (16%), Positives = 119/295 (40%), Gaps = 16/295 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 49 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 103
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L ++ ++ + + V + V+ + + AC ++
Sbjct: 104 NITKLSIPTDSIWVPD--ILINEFVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNG 177
+P D+Q+C + S+ ++ Q + + + + L L
Sbjct: 161 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 220
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
+ ++ Y+ + Y R+ +++ PS ++++ F+L ++ G
Sbjct: 221 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS--GERVSFKI 278
Query: 238 XXXXXXXXFTGLRADIPPVAYV--KALDLWMAGCMMFVFAALGEFV-VVKVLDKQ 289
F + +D P + + ++ CM + +L E + +V+++ KQ
Sbjct: 279 TLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 333
>AF498984-1|AAM21131.1| 478|Homo sapiens 5-hydroxytryptamine
receptor 3A protein.
Length = 478
Score = 47.6 bits (108), Expect = 8e-05
Identities = 50/295 (16%), Positives = 119/295 (40%), Gaps = 16/295 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 49 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 103
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L ++ ++ + + V + V+ + + AC ++
Sbjct: 104 NITKLSIPTDSIWVPD--ILINEFVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNG 177
+P D+Q+C + S+ ++ Q + + + + L L
Sbjct: 161 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 220
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXX 237
+ ++ Y+ + Y R+ +++ PS ++++ F+L ++ G
Sbjct: 221 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYLPPNS--GERVSFKI 278
Query: 238 XXXXXXXXFTGLRADIPPVAYV--KALDLWMAGCMMFVFAALGEFV-VVKVLDKQ 289
F + +D P + + ++ CM + +L E + +V+++ KQ
Sbjct: 279 TLLLGYSVFLIIVSDTLPATAIGTPLIGVYFVVCMALLVISLAETIFIVRLVHKQ 333
>AJ295237-1|CAC16144.1| 450|Homo sapiens neuronal nicotinic
acetylcholine receptor subunit4 protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 54/279 (19%), Positives = 113/279 (40%), Gaps = 15/279 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A Q + V + + + ++ + + ++IRQ W+++ L+ + + G D
Sbjct: 45 LRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYG-GLDA 103
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P +W PD N + ++V L + VR+ A +C+++
Sbjct: 104 IRIPSSL---VWRPDIVLYNK--ADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDV 158
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEE-TNGY 178
+P D Q C + S+++ ++ R A ++ ++ +++ + G P R T G
Sbjct: 159 AAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASLADFVENVEWRVLGMPARRRVLTYGC 218
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
+ Y + R+ ++ P L+ +L+ +F L D+ G
Sbjct: 219 CSEP---YPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAFHLPADS--GEKVSLGVT 273
Query: 239 XXXXXXXFTGLRAD-IPPVAYVKAL-DLWMAGCMMFVFA 275
F L A+ +PP V + +MA M F+
Sbjct: 274 VLLALTVFQLLLAESMPPAESVPLIGKYYMATMTMVTFS 312
>AJ278118-1|CAC20435.1| 450|Homo sapiens neuronal nicotinic
acetylcholine alpha10 subunit protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 54/279 (19%), Positives = 113/279 (40%), Gaps = 15/279 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A Q + V + + + ++ + + ++IRQ W+++ L+ + + G D
Sbjct: 45 LRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYG-GLDA 103
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P +W PD N + ++V L + VR+ A +C+++
Sbjct: 104 IRIPSSL---VWRPDIVLYNK--ADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDV 158
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEE-TNGY 178
+P D Q C + S+++ ++ R A ++ ++ +++ + G P R T G
Sbjct: 159 AAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASLADFVENVEWRVLGMPARRRVLTYGC 218
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
+ Y + R+ ++ P L+ +L+ +F L D+ G
Sbjct: 219 CSEP---YPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAFHLPADS--GEKVSLGVT 273
Query: 239 XXXXXXXFTGLRAD-IPPVAYVKAL-DLWMAGCMMFVFA 275
F L A+ +PP V + +MA M F+
Sbjct: 274 VLLALTVFQLLLAESMPPAESVPLIGKYYMATMTMVTFS 312
>AF327367-1|AAK14333.1| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 54/279 (19%), Positives = 113/279 (40%), Gaps = 15/279 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A Q + V + + + ++ + + ++IRQ W+++ L+ + + G D
Sbjct: 45 LRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYG-GLDA 103
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P +W PD N + ++V L + VR+ A +C+++
Sbjct: 104 IRIPSSL---VWRPDIVLYNK--ADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDV 158
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEE-TNGY 178
+P D Q C + S+++ ++ R A ++ ++ +++ + G P R T G
Sbjct: 159 AAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASLADFVENVEWRVLGMPARRRVLTYGC 218
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
+ Y + R+ ++ P L+ +L+ +F L D+ G
Sbjct: 219 CSEP---YPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAFHLPADS--GEKVSLGVT 273
Query: 239 XXXXXXXFTGLRAD-IPPVAYVKAL-DLWMAGCMMFVFA 275
F L A+ +PP V + +MA M F+
Sbjct: 274 VLLALTVFQLLLAESMPPAESVPLIGKYYMATMTMVTFS 312
>AF199235-1|AAG00795.2| 450|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 10 protein.
Length = 450
Score = 47.2 bits (107), Expect = 1e-04
Identities = 54/279 (19%), Positives = 113/279 (40%), Gaps = 15/279 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A Q + V + + + ++ + + ++IRQ W+++ L+ + + G D
Sbjct: 45 LRPVADTDQTLNVTLEVTLSQIIDMDERNQVLTLYLWIRQEWTDAYLRWDPNAYG-GLDA 103
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P +W PD N + ++V L + VR+ A +C+++
Sbjct: 104 IRIPSSL---VWRPDIVLYNK--ADAQPPGSASTNVVLRHDGAVRWDAPAITRSSCRVDV 158
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEE-TNGY 178
+P D Q C + S+++ ++ R A ++ ++ +++ + G P R T G
Sbjct: 159 AAFPFDAQHCGLTFGSWTHGGHQLDVRPRGAAASLADFVENVEWRVLGMPARRRVLTYGC 218
Query: 179 MIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXX 238
+ Y + R+ ++ P L+ +L+ +F L D+ G
Sbjct: 219 CSEP---YPDVTFTLLLRRRAAAYVCNLLLPCVLISLLAPLAFHLPADS--GEKVSLGVT 273
Query: 239 XXXXXXXFTGLRAD-IPPVAYVKAL-DLWMAGCMMFVFA 275
F L A+ +PP V + +MA M F+
Sbjct: 274 VLLALTVFQLLLAESMPPAESVPLIGKYYMATMTMVTFS 312
>AM293589-1|CAL25321.1| 430|Homo sapiens 5-hydroxytryptamine
receptor 3 subunit B protein.
Length = 430
Score = 46.8 bits (106), Expect = 1e-04
Identities = 39/224 (17%), Positives = 97/224 (43%), Gaps = 8/224 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V ++V + ++ E+ + ++ ++ W++ L +F+E +
Sbjct: 36 VRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWNSSMFDEIRE- 94
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
++LP +W PD + ++ +I E + V + + T+ + + AC +E
Sbjct: 95 ISLP---LSAIWAPD--IIINEFVDI-ERSPDLPYVYVNSSGTIENYKPIQVVSACSLET 148
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELK-LLQYHIGQPLRLEETNGYM 179
+P D+Q+C + +S ++ + V + + I + K L + L + T +
Sbjct: 149 YAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWELLSVSSTYSIL 208
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
G ++++ R +++ PS ++++ SF+L
Sbjct: 209 QSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYL 252
>Y08416-1|CAA69693.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/150 (22%), Positives = 75/150 (50%), Gaps = 18/150 (12%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q + ++ + + + S+N + +++++Q W++ RL +E G +
Sbjct: 44 IRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYE-GVNI 102
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARM----HAII-- 114
+ +P + +W PD N+ A+ T++ V++Y N VR + + AI
Sbjct: 103 LRIPAK---RIWLPDIVLYNN-----ADGTYE---VSVYTNLIVRSNGSVLWLPPAIYKS 151
Query: 115 ACQMEFQLYPMDIQSCPIYIESFSYSNQKV 144
AC++E + +P D Q+C + S++Y + ++
Sbjct: 152 ACKIEVKYFPFDQQNCTLKFRSWTYDHTEI 181
>U62439-1|AAB40117.1| 498|Homo sapiens nicotinic acetylcholine
receptor beta4 subunit precursor protein.
Length = 498
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/150 (22%), Positives = 75/150 (50%), Gaps = 18/150 (12%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q + ++ + + + S+N + +++++Q W++ RL +E G +
Sbjct: 44 IRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYE-GVNI 102
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARM----HAII-- 114
+ +P + +W PD N+ A+ T++ V++Y N VR + + AI
Sbjct: 103 LRIPAK---RIWLPDIVLYNN-----ADGTYE---VSVYTNLIVRSNGSVLWLPPAIYKS 151
Query: 115 ACQMEFQLYPMDIQSCPIYIESFSYSNQKV 144
AC++E + +P D Q+C + S++Y + ++
Sbjct: 152 ACKIEVKYFPFDQQNCTLKFRSWTYDHTEI 181
>U48861-1|AAA92123.1| 498|Homo sapiens beta 4 nicotinic
acetylcholine receptor subunit protein.
Length = 498
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/150 (22%), Positives = 75/150 (50%), Gaps = 18/150 (12%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q + ++ + + + S+N + +++++Q W++ RL +E G +
Sbjct: 44 IRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYE-GVNI 102
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARM----HAII-- 114
+ +P + +W PD N+ A+ T++ V++Y N VR + + AI
Sbjct: 103 LRIPAK---RIWLPDIVLYNN-----ADGTYE---VSVYTNLIVRSNGSVLWLPPAIYKS 151
Query: 115 ACQMEFQLYPMDIQSCPIYIESFSYSNQKV 144
AC++E + +P D Q+C + S++Y + ++
Sbjct: 152 ACKIEVKYFPFDQQNCTLKFRSWTYDHTEI 181
>BC113575-1|AAI13576.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/224 (19%), Positives = 97/224 (43%), Gaps = 9/224 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V I + + ++ + ++IRQ W ++ L D ++ G D
Sbjct: 46 LRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYD-GLDS 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N E +E + ++V L + + + A +C ++
Sbjct: 105 IRIPS---DLVWRPDIVLYNKADDESSEPVN--TNVVLRYDGLITWDAPAITKSSCVVDV 159
Query: 121 QLYPMDIQSCPIYIESFSYS-NQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+P D Q C + S++Y+ NQ F ++G ++ ++ +++ + ++ Y
Sbjct: 160 TYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSG-DLSDFIEDVEWEVHGMPAVKNVISYG 218
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ Y + +R+ +++ P L+ L+ SF+L
Sbjct: 219 CCSE-PYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYL 261
>BC113549-1|AAI13550.1| 479|Homo sapiens cholinergic receptor,
nicotinic, alpha 9 protein.
Length = 479
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/224 (19%), Positives = 97/224 (43%), Gaps = 9/224 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V I + + ++ + ++IRQ W ++ L D ++ G D
Sbjct: 46 LRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYD-GLDS 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N E +E + ++V L + + + A +C ++
Sbjct: 105 IRIPS---DLVWRPDIVLYNKADDESSEPVN--TNVVLRYDGLITWDAPAITKSSCVVDV 159
Query: 121 QLYPMDIQSCPIYIESFSYS-NQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+P D Q C + S++Y+ NQ F ++G ++ ++ +++ + ++ Y
Sbjct: 160 TYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSG-DLSDFIEDVEWEVHGMPAVKNVISYG 218
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ Y + +R+ +++ P L+ L+ SF+L
Sbjct: 219 CCSE-PYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYL 261
>BC096082-1|AAH96082.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/150 (22%), Positives = 75/150 (50%), Gaps = 18/150 (12%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q + ++ + + + S+N + +++++Q W++ RL +E G +
Sbjct: 44 IRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYE-GVNI 102
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARM----HAII-- 114
+ +P + +W PD N+ A+ T++ V++Y N VR + + AI
Sbjct: 103 LRIPAK---RIWLPDIVLYNN-----ADGTYE---VSVYTNLIVRSNGSVLWLPPAIYKS 151
Query: 115 ACQMEFQLYPMDIQSCPIYIESFSYSNQKV 144
AC++E + +P D Q+C + S++Y + ++
Sbjct: 152 ACKIEVKYFPFDQQNCTLKFRSWTYDHTEI 181
>BC096080-1|AAH96080.1| 498|Homo sapiens cholinergic receptor,
nicotinic, beta 4 protein.
Length = 498
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/150 (22%), Positives = 75/150 (50%), Gaps = 18/150 (12%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q + ++ + + + S+N + +++++Q W++ RL +E G +
Sbjct: 44 IRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYE-GVNI 102
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARM----HAII-- 114
+ +P + +W PD N+ A+ T++ V++Y N VR + + AI
Sbjct: 103 LRIPAK---RIWLPDIVLYNN-----ADGTYE---VSVYTNLIVRSNGSVLWLPPAIYKS 151
Query: 115 ACQMEFQLYPMDIQSCPIYIESFSYSNQKV 144
AC++E + +P D Q+C + S++Y + ++
Sbjct: 152 ACKIEVKYFPFDQQNCTLKFRSWTYDHTEI 181
>AY123244-1|AAM74523.1| 479|Homo sapiens nicotinic acetylcholine
receptor subunit alpha 9 protein.
Length = 479
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/224 (19%), Positives = 97/224 (43%), Gaps = 9/224 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V I + + ++ + ++IRQ W ++ L D ++ G D
Sbjct: 46 LRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYD-GLDS 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N E +E + ++V L + + + A +C ++
Sbjct: 105 IRIPS---DLVWRPDIVLYNKADDESSEPVN--TNVVLRYDGLITWDAPAITKSSCVVDV 159
Query: 121 QLYPMDIQSCPIYIESFSYS-NQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+P D Q C + S++Y+ NQ F ++G ++ ++ +++ + ++ Y
Sbjct: 160 TYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSG-DLSDFIEDVEWEVHGMPAVKNVISYG 218
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ Y + +R+ +++ P L+ L+ SF+L
Sbjct: 219 CCSE-PYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYL 261
>AJ243342-1|CAB65091.1| 479|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 479
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/224 (19%), Positives = 97/224 (43%), Gaps = 9/224 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V I + + ++ + ++IRQ W ++ L D ++ G D
Sbjct: 46 LRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYD-GLDS 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N E +E + ++V L + + + A +C ++
Sbjct: 105 IRIPS---DLVWRPDIVLYNKADDESSEPVN--TNVVLRYDGLITWDAPAITKSSCVVDV 159
Query: 121 QLYPMDIQSCPIYIESFSYS-NQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+P D Q C + S++Y+ NQ F ++G ++ ++ +++ + ++ Y
Sbjct: 160 TYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSG-DLSDFIEDVEWEVHGMPAVKNVISYG 218
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ Y + +R+ +++ P L+ L+ SF+L
Sbjct: 219 CCSE-PYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYL 261
>AF306329-1|AAL02062.1| 498|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 4 subunit protein.
Length = 498
Score = 46.0 bits (104), Expect = 2e-04
Identities = 34/150 (22%), Positives = 75/150 (50%), Gaps = 18/150 (12%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q + ++ + + + S+N + +++++Q W++ RL +E G +
Sbjct: 44 IRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRYE-GVNI 102
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARM----HAII-- 114
+ +P + +W PD N+ A+ T++ V++Y N VR + + AI
Sbjct: 103 LRIPAK---RIWLPDIVLYNN-----ADGTYE---VSVYTNLIVRSNGSVLWLPPAIYKS 151
Query: 115 ACQMEFQLYPMDIQSCPIYIESFSYSNQKV 144
AC++E + +P D Q+C + S++Y + ++
Sbjct: 152 ACKIEVKYFPFDQQNCTLKFRSWTYDHTEI 181
>AF227732-1|AAF61920.1| 470|Homo sapiens nicotinic acetylcholine
receptor alpha 9 subunit protein.
Length = 470
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/224 (19%), Positives = 97/224 (43%), Gaps = 9/224 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V I + + ++ + ++IRQ W ++ L D ++ G D
Sbjct: 40 LRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYD-GLDS 98
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N E +E + ++V L + + + A +C ++
Sbjct: 99 IRIPS---DLVWRPDIVLYNKADDESSEPVN--TNVVLRYDGLITWDAPAITKSSCVVDV 153
Query: 121 QLYPMDIQSCPIYIESFSYS-NQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+P D Q C + S++Y+ NQ F ++G ++ ++ +++ + ++ Y
Sbjct: 154 TYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSG-DLSDFIEDVEWEVHGMPAVKNVISYG 212
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ Y + +R+ +++ P L+ L+ SF+L
Sbjct: 213 CCSE-PYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYL 255
>AC118275-1|AAY40986.1| 479|Homo sapiens unknown protein.
Length = 479
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/224 (19%), Positives = 97/224 (43%), Gaps = 9/224 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + + V I + + ++ + ++IRQ W ++ L D ++ G D
Sbjct: 46 LRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHDAYLTWDRDQYD-GLDS 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
+ +P D +W PD N E +E + ++V L + + + A +C ++
Sbjct: 105 IRIPS---DLVWRPDIVLYNKADDESSEPVN--TNVVLRYDGLITWDAPAITKSSCVVDV 159
Query: 121 QLYPMDIQSCPIYIESFSYS-NQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYM 179
+P D Q C + S++Y+ NQ F ++G ++ ++ +++ + ++ Y
Sbjct: 160 TYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSG-DLSDFIEDVEWEVHGMPAVKNVISYG 218
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ Y + +R+ +++ P L+ L+ SF+L
Sbjct: 219 CCSE-PYPDVTFTLLLKRRSSFYIVNLLIPCVLISFLAPLSFYL 261
>AF169255-1|AAF03691.1| 441|Homo sapiens 5-hydroxytryptamine 3
receptor B subunit protein.
Length = 441
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/224 (17%), Positives = 96/224 (42%), Gaps = 8/224 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V ++V + ++ E+ + ++ ++ W++ L +F+E +
Sbjct: 47 VRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWNSSMFDEIRE- 105
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
++LP +W PD + ++ +I E V + + T+ + + AC +E
Sbjct: 106 ISLP---LSAIWAPD--IIINEFVDI-ERYPDLPYVYVNSSGTIENYKPIQVVSACSLET 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELK-LLQYHIGQPLRLEETNGYM 179
+P D+Q+C + +S ++ + V + + I + K L + L + T +
Sbjct: 160 YAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWELLSVSSTYSIL 219
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
G ++++ R +++ PS ++++ SF+L
Sbjct: 220 QSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYL 263
>AF080582-1|AAD12242.1| 441|Homo sapiens 5-hydroxytryptamine 3
receptor B subunit precursor protein.
Length = 441
Score = 45.6 bits (103), Expect = 3e-04
Identities = 39/224 (17%), Positives = 96/224 (42%), Gaps = 8/224 (3%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V ++V + ++ E+ + ++ ++ W++ L +F+E +
Sbjct: 47 VRPVYNWTKATTVYLDLFVHAILDVDAENQILKTSVWYQEVWNDEFLSWNSSMFDEIRE- 105
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
++LP +W PD + ++ +I E V + + T+ + + AC +E
Sbjct: 106 ISLP---LSAIWAPD--IIINEFVDI-ERYPDLPYVYVNSSGTIENYKPIQVVSACSLET 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELK-LLQYHIGQPLRLEETNGYM 179
+P D+Q+C + +S ++ + V + + I + K L + L + T +
Sbjct: 160 YAFPFDVQNCSLTFKSILHTVEDVDLAFLRSPEDIQHDKKAFLNDSEWELLSVSSTYSIL 219
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
G ++++ R +++ PS ++++ SF+L
Sbjct: 220 QSSAGGFAQIQFNVVMRRHPLVYVVSLLIPSIFLMLVDLGSFYL 263
>AJ003078-1|CAA05851.1| 510|Homo sapiens serotonin receptor
protein.
Length = 510
Score = 44.0 bits (99), Expect = 0.001
Identities = 39/226 (17%), Positives = 93/226 (41%), Gaps = 11/226 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 49 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 103
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L ++ ++ + + V + V+ + + AC ++
Sbjct: 104 NITKLSIPTDSIWVPD--ILINEFVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 160
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLR--LEETNG 177
+P D+Q+C + S+ ++ Q + + + + L L
Sbjct: 161 IYNFPFDVQNCSLTFTSWLHTIQDINISLWRLPEKVKSDRSVFMNQGEWELLGVLPYFRE 220
Query: 178 YMIDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWL 223
+ ++ Y+ + Y R+ +++ PS ++++ F+L
Sbjct: 221 FSMESSNYYAEMKFYVVIRRRPLFYVVSLLLPSIFLMVMDIVGFYL 266
>AF228447-1|AAF62508.1| 96|Homo sapiens gamma-aminobutyric acid
receptor alpha 5 subunit protein.
Length = 96
Score = 44.0 bits (99), Expect = 0.001
Identities = 25/97 (25%), Positives = 45/97 (46%), Gaps = 5/97 (5%)
Query: 13 VEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFFDNLW 72
V IYV ++ +M++ +D+F RQ+W + RL+ F+ + L +W
Sbjct: 5 VRTDIYVTSFGPVSDTEMEYTIDVFFRQSWKDERLR-----FKGPMQRLPLNNLLASKIW 59
Query: 73 HPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSAR 109
PD +F N K + +T + L + T+ Y+ R
Sbjct: 60 TPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYTMR 96
>Y08415-1|CAA69692.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.002
Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V V+ + + + S++ + ++++ Q W + RL + F+
Sbjct: 46 IRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKK- 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V LP + ++W PD N+ + E++ ++V Y ++ AC++E
Sbjct: 105 VRLPSK---HIWLPDVVLYNN-ADGMYEVSFYSNAVVSYDGSIFWLPPAIYKS-ACKIEV 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYM 179
+ +P D Q+C + S++Y ++ +++ ++ I P R E
Sbjct: 160 KHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNEN---- 215
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D Y + F R+ + I P L+ L+ F+L D
Sbjct: 216 -PDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSD 261
>Y00762-1|CAA68731.1| 457|Homo sapiens protein ( Human mRNA for
muscle acetylcholine receptor alpha-subunit. ).
Length = 457
Score = 43.2 bits (97), Expect = 0.002
Identities = 53/276 (19%), Positives = 113/276 (40%), Gaps = 12/276 (4%)
Query: 12 IVEFSIYVVDVNSINVEDMDFRVDMFIR--QTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
+VE ++ + + INV++++ V +R Q W + L+ D + G + +P E
Sbjct: 48 VVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYG-GVKKIHIPSE--- 103
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
+W PD N+ + A + KF+ V L + ++ C++ +P D Q+
Sbjct: 104 KIWRPDLVLYNNADGDFAIV--KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQN 161
Query: 130 CPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRL 189
C + + +++Y V ++ ++ ++ I + + + Y D Y +
Sbjct: 162 CSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDI 221
Query: 190 VVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGL 249
+F +R + ++ P L L+ F+L D+ G F +
Sbjct: 222 TYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDS--GEKMTLSISVLLSLTVFLLV 279
Query: 250 RADIPP--VAYVKALDLWMAGCMMFVFAALGEFVVV 283
++ P + V + +M M+FV A++ V+V
Sbjct: 280 IVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIV 315
>X53179-1|CAA37320.1| 502|Homo sapiens precursor peptide (AA -25 to
477) protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.002
Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V V+ + + + S++ + ++++ Q W + RL + F+
Sbjct: 46 IRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKK- 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V LP + ++W PD N+ + E++ ++V Y ++ AC++E
Sbjct: 105 VRLPSK---HIWLPDVVLYNN-ADGMYEVSFYSNAVVSYDGSIFWLPPAIYKS-ACKIEV 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYM 179
+ +P D Q+C + S++Y ++ +++ ++ I P R E
Sbjct: 160 KHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNEN---- 215
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D Y + F R+ + I P L+ L+ F+L D
Sbjct: 216 -PDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSD 261
>X02502-1|CAA26344.1| 457|Homo sapiens acetylcholine receptor
protein.
Length = 457
Score = 43.2 bits (97), Expect = 0.002
Identities = 53/276 (19%), Positives = 113/276 (40%), Gaps = 12/276 (4%)
Query: 12 IVEFSIYVVDVNSINVEDMDFRVDMFIR--QTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
+VE ++ + + INV++++ V +R Q W + L+ D + G + +P E
Sbjct: 48 VVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYG-GVKKIHIPSE--- 103
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
+W PD N+ + A + KF+ V L + ++ C++ +P D Q+
Sbjct: 104 KIWRPDLVLYNNADGDFAIV--KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQN 161
Query: 130 CPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRL 189
C + + +++Y V ++ ++ ++ I + + + Y D Y +
Sbjct: 162 CSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDI 221
Query: 190 VVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGL 249
+F +R + ++ P L L+ F+L D+ G F +
Sbjct: 222 TYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDS--GEKMTLSISVLLSLTVFLLV 279
Query: 250 RADIPP--VAYVKALDLWMAGCMMFVFAALGEFVVV 283
++ P + V + +M M+FV A++ V+V
Sbjct: 280 IVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIV 315
>U62437-1|AAB40115.1| 502|Homo sapiens nicotinic acetylcholine
receptor beta2 subunit precursor protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.002
Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V V+ + + + S++ + ++++ Q W + RL + F+
Sbjct: 46 IRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKK- 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V LP + ++W PD N+ + E++ ++V Y ++ AC++E
Sbjct: 105 VRLPSK---HIWLPDVVLYNN-ADGMYEVSFYSNAVVSYDGSIFWLPPAIYKS-ACKIEV 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYM 179
+ +P D Q+C + S++Y ++ +++ ++ I P R E
Sbjct: 160 KHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNEN---- 215
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D Y + F R+ + I P L+ L+ F+L D
Sbjct: 216 -PDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSD 261
>S77094-1|AAD14247.1| 457|Homo sapiens nicotinic acetylcholine
receptor alpha subunit|AChR protein.
Length = 457
Score = 43.2 bits (97), Expect = 0.002
Identities = 53/276 (19%), Positives = 113/276 (40%), Gaps = 12/276 (4%)
Query: 12 IVEFSIYVVDVNSINVEDMDFRVDMFIR--QTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
+VE ++ + + INV++++ V +R Q W + L+ D + G + +P E
Sbjct: 48 VVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYG-GVKKIHIPSE--- 103
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
+W PD N+ + A + KF+ V L + ++ C++ +P D Q+
Sbjct: 104 KIWRPDLVLYNNADGDFAIV--KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQN 161
Query: 130 CPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRL 189
C + + +++Y V ++ ++ ++ I + + + Y D Y +
Sbjct: 162 CSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDI 221
Query: 190 VVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGL 249
+F +R + ++ P L L+ F+L D+ G F +
Sbjct: 222 TYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDS--GEKMTLSISVLLSLTVFLLV 279
Query: 250 RADIPP--VAYVKALDLWMAGCMMFVFAALGEFVVV 283
++ P + V + +M M+FV A++ V+V
Sbjct: 280 IVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIV 315
>BC075041-1|AAH75041.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.002
Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V V+ + + + S++ + ++++ Q W + RL + F+
Sbjct: 46 IRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKK- 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V LP + ++W PD N+ + E++ ++V Y ++ AC++E
Sbjct: 105 VRLPSK---HIWLPDVVLYNN-ADGMYEVSFYSNAVVSYDGSIFWLPPAIYKS-ACKIEV 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYM 179
+ +P D Q+C + S++Y ++ +++ ++ I P R E
Sbjct: 160 KHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNEN---- 215
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D Y + F R+ + I P L+ L+ F+L D
Sbjct: 216 -PDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSD 261
>BC075040-1|AAH75040.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.002
Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V V+ + + + S++ + ++++ Q W + RL + F+
Sbjct: 46 IRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKK- 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V LP + ++W PD N+ + E++ ++V Y ++ AC++E
Sbjct: 105 VRLPSK---HIWLPDVVLYNN-ADGMYEVSFYSNAVVSYDGSIFWLPPAIYKS-ACKIEV 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYM 179
+ +P D Q+C + S++Y ++ +++ ++ I P R E
Sbjct: 160 KHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNEN---- 215
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D Y + F R+ + I P L+ L+ F+L D
Sbjct: 216 -PDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSD 261
>AL592078-3|CAI16184.1| 502|Homo sapiens cholinergic receptor,
nicotinic, beta 2 (neuronal) protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.002
Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V V+ + + + S++ + ++++ Q W + RL + F+
Sbjct: 46 IRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKK- 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V LP + ++W PD N+ + E++ ++V Y ++ AC++E
Sbjct: 105 VRLPSK---HIWLPDVVLYNN-ADGMYEVSFYSNAVVSYDGSIFWLPPAIYKS-ACKIEV 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYM 179
+ +P D Q+C + S++Y ++ +++ ++ I P R E
Sbjct: 160 KHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNEN---- 215
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D Y + F R+ + I P L+ L+ F+L D
Sbjct: 216 -PDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSD 261
>AJ001935-1|CAA05108.1| 504|Homo sapiens CHRNB2 protein.
Length = 504
Score = 43.2 bits (97), Expect = 0.002
Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V V+ + + + S++ + ++++ Q W + RL + F+
Sbjct: 46 IRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKK- 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V LP + ++W PD N+ + E++ ++V Y ++ AC++E
Sbjct: 105 VRLPSK---HIWLPDVVLYNN-ADGMYEVSFYSNAVVSYDGSIFWLPPAIYKS-ACKIEV 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYM 179
+ +P D Q+C + S++Y ++ +++ ++ I P R E
Sbjct: 160 KHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNEN---- 215
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D Y + F R+ + I P L+ L+ F+L D
Sbjct: 216 -PDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSD 261
>AF077186-1|AAD45422.1| 502|Homo sapiens neuronal nicotinic
acetylcholine receptor beta 2 protein.
Length = 502
Score = 43.2 bits (97), Expect = 0.002
Identities = 44/227 (19%), Positives = 92/227 (40%), Gaps = 12/227 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V V+ + + + S++ + ++++ Q W + RL + F+
Sbjct: 46 IRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDNMKK- 104
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V LP + ++W PD N+ + E++ ++V Y ++ AC++E
Sbjct: 105 VRLPSK---HIWLPDVVLYNN-ADGMYEVSFYSNAVVSYDGSIFWLPPAIYKS-ACKIEV 159
Query: 121 QLYPMDIQSCPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHI-GQPLRLEETNGYM 179
+ +P D Q+C + S++Y ++ +++ ++ I P R E
Sbjct: 160 KHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWDIVALPGRRNEN---- 215
Query: 180 IDKDGNYSRLVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLD 226
D Y + F R+ + I P L+ L+ F+L D
Sbjct: 216 -PDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSD 261
>AC018890-1|AAY14687.1| 457|Homo sapiens unknown protein.
Length = 457
Score = 43.2 bits (97), Expect = 0.002
Identities = 53/276 (19%), Positives = 113/276 (40%), Gaps = 12/276 (4%)
Query: 12 IVEFSIYVVDVNSINVEDMDFRVDMFIR--QTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
+VE ++ + + INV++++ V +R Q W + L+ D + G + +P E
Sbjct: 48 VVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYG-GVKKIHIPSE--- 103
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
+W PD N+ + A + KF+ V L + ++ C++ +P D Q+
Sbjct: 104 KIWRPDLVLYNNADGDFAIV--KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQN 161
Query: 130 CPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRL 189
C + + +++Y V ++ ++ ++ I + + + Y D Y +
Sbjct: 162 CSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDI 221
Query: 190 VVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTGL 249
+F +R + ++ P L L+ F+L D+ G F +
Sbjct: 222 TYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDS--GEKMTLSISVLLSLTVFLLV 279
Query: 250 RADIPP--VAYVKALDLWMAGCMMFVFAALGEFVVV 283
++ P + V + +M M+FV A++ V+V
Sbjct: 280 IVELIPSTSSAVPLIGKYMLFTMVFVIASIIITVIV 315
>X66403-1|CAA47030.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit CHRNE protein.
Length = 493
Score = 42.7 bits (96), Expect = 0.002
Identities = 34/157 (21%), Positives = 70/157 (44%), Gaps = 8/157 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP V + + + ++ S+N ++ ++I W + RL +D F G + +
Sbjct: 40 RPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFG-GIETL 98
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+P E +W P+ L + + + + ++V +Y +V + C +E
Sbjct: 99 RVPSEL---VWLPE-IVLENNIDGQFGVAYD-ANVLVYEGGSVTWLPPAIYRSVCAVEVT 153
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWS--EAGVTIN 156
+P D Q+C + S +Y+ ++V F ++ G TIN
Sbjct: 154 YFPFDWQNCSLIFRSQTYNAEEVEFTFAVDNDGKTIN 190
>AF105999-1|AAD24503.1| 493|Homo sapiens acetylcholine receptor
epsilon subunit protein.
Length = 493
Score = 42.7 bits (96), Expect = 0.002
Identities = 34/157 (21%), Positives = 70/157 (44%), Gaps = 8/157 (5%)
Query: 2 RPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHV 61
RP V + + + ++ S+N ++ ++I W + RL +D F G + +
Sbjct: 40 RPVREPEDTVTISLKVTLTNLISLNEKEETLTTSVWIGIDWQDYRLNYSKDDFG-GIETL 98
Query: 62 TLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQ 121
+P E +W P+ L + + + + ++V +Y +V + C +E
Sbjct: 99 RVPSEL---VWLPE-IVLENNIDGQFGVAYD-ANVLVYEGGSVTWLPPAIYRSVCAVEVT 153
Query: 122 LYPMDIQSCPIYIESFSYSNQKVRFRWS--EAGVTIN 156
+P D Q+C + S +Y+ ++V F ++ G TIN
Sbjct: 154 YFPFDWQNCSLIFRSQTYNAEEVEFTFAVDNDGKTIN 190
>X68275-1|CAA48336.1| 451|Homo sapiens nicotinic receptor beta 4
subunit protein.
Length = 451
Score = 42.3 bits (95), Expect = 0.003
Identities = 33/142 (23%), Positives = 72/142 (50%), Gaps = 18/142 (12%)
Query: 9 QPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDHVTLPPEFF 68
Q + ++ + + + S+N D +++++Q W++ RL +E G + + +P +
Sbjct: 5 QLISIKLQLSLAQLISVNERDEIMTTNVWLKQEWTDYRLTWNSSRYE-GVNILRIPAK-- 61
Query: 69 DNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARM----HAII--ACQMEFQL 122
+W PD N+ A+ T++ V++Y N VR + + AI AC++E +
Sbjct: 62 -RIWLPDIVLYNN-----ADGTYE---VSVYTNLIVRSNGSVLWLPPAIYKSACKIEVKY 112
Query: 123 YPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y + ++
Sbjct: 113 FPFDQQNCTLKFRSWTYDHTEI 134
>BC006314-1|AAH06314.1| 269|Homo sapiens CHRNA1 protein protein.
Length = 269
Score = 41.9 bits (94), Expect = 0.004
Identities = 42/218 (19%), Positives = 92/218 (42%), Gaps = 8/218 (3%)
Query: 12 IVEFSIYVVDVNSINVEDMDFRVDMFIR--QTWSESRLQLPEDIFEEGDDHVTLPPEFFD 69
+VE ++ + + INV++++ V +R Q W + L+ D + G + +P E
Sbjct: 48 VVEVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWNPDDYG-GVKKIHIPSE--- 103
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
+W PD N+ + A + KF+ V L + ++ C++ +P D Q+
Sbjct: 104 KIWRPDLVLYNNADGDFAIV--KFTKVLLQYTGHITWTPPAIFKSYCEIIVTHFPFDEQN 161
Query: 130 CPIYIESFSYSNQKVRFRWSEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSRL 189
C + + +++Y V ++ ++ ++ I + + + Y D Y +
Sbjct: 162 CSMKLGTWTYDGSVVAINPESDQPDLSNFMESGEWVIKESRGWKHSVTYSCCPDTPYLDI 221
Query: 190 VVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDA 227
+F +R + ++ P L L+ F+L D+
Sbjct: 222 TYHFVMQRLPLYFIVNVIIPCLLFSFLTGLVFYLPTDS 259
>Y08419-1|CAA69696.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 41.5 bits (93), Expect = 0.005
Identities = 28/144 (19%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + ++F + + + ++ ++ +++++Q W + +L+ D + G
Sbjct: 62 VRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDY--GGIK 119
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V P D++W PD ++ + K +V Y N TV ++ + +C ++
Sbjct: 120 VIRVPS--DSVWTPDIVLFDNADGRFEGTSTK--TVIRY-NGTVTWTPPANYKSSCTIDV 174
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D+Q+C + S++Y +V
Sbjct: 175 TFFPFDLQNCSMKFGSWTYDGSQV 198
>X01715-1|CAA25861.1| 520|Homo sapiens acetylcholine receptor gamma
chain precursor protein.
Length = 520
Score = 41.5 bits (93), Expect = 0.005
Identities = 37/157 (23%), Positives = 70/157 (44%), Gaps = 9/157 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP R V V + + ++ S+N + +++I W + RL+ P D EG
Sbjct: 44 LRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPRDY--EGLW 101
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P +W PD L + V + E+ + +V + + + + AC +
Sbjct: 102 VLRVPSTM---VWRPD-IVLENNVDGVFEVA-LYCNVLVSPDGCIYWLPPAIFRSACSIS 156
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWS-EAGVTI 155
+P D Q+C + +S +YS ++ + S E G TI
Sbjct: 157 VTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQEDGQTI 193
>U62434-1|AAB40112.1| 468|Homo sapiens nicotinic acetylcholine
receptor alpha5 subunit precursor protein.
Length = 468
Score = 41.5 bits (93), Expect = 0.005
Identities = 28/144 (19%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + ++F + + + ++ ++ +++++Q W + +L+ D + G
Sbjct: 62 VRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDY--GGIK 119
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V P D++W PD ++ + K +V Y N TV ++ + +C ++
Sbjct: 120 VIRVPS--DSVWTPDIVLFDNADGRFEGTSTK--TVIRY-NGTVTWTPPANYKSSCTIDV 174
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D+Q+C + S++Y +V
Sbjct: 175 TFFPFDLQNCSMKFGSWTYDGSQV 198
>BC033639-1|AAH33639.1| 468|Homo sapiens cholinergic receptor,
nicotinic, alpha 5 protein.
Length = 468
Score = 41.5 bits (93), Expect = 0.005
Identities = 28/144 (19%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + ++F + + + ++ ++ +++++Q W + +L+ D + G
Sbjct: 62 VRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDY--GGIK 119
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V P D++W PD ++ + K +V Y N TV ++ + +C ++
Sbjct: 120 VIRVPS--DSVWTPDIVLFDNADGRFEGTSTK--TVIRY-NGTVTWTPPANYKSSCTIDV 174
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D+Q+C + S++Y +V
Sbjct: 175 TFFPFDLQNCSMKFGSWTYDGSQV 198
>AJ306481-1|CAC34820.1| 468|Homo sapiens neuronal nicotinic
acetylcholine receptor alpha-5subunit protein.
Length = 468
Score = 41.5 bits (93), Expect = 0.005
Identities = 28/144 (19%), Positives = 67/144 (46%), Gaps = 7/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + ++F + + + ++ ++ +++++Q W + +L+ D + G
Sbjct: 62 VRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDY--GGIK 119
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V P D++W PD ++ + K +V Y N TV ++ + +C ++
Sbjct: 120 VIRVPS--DSVWTPDIVLFDNADGRFEGTSTK--TVIRY-NGTVTWTPPANYKSSCTIDV 174
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D+Q+C + S++Y +V
Sbjct: 175 TFFPFDLQNCSMKFGSWTYDGSQV 198
>AJ003080-1|CAA05853.1| 238|Homo sapiens serotonin receptor
protein.
Length = 238
Score = 41.5 bits (93), Expect = 0.005
Identities = 29/142 (20%), Positives = 66/142 (46%), Gaps = 9/142 (6%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP +P V + V + +++ ++ ++ RQ W++ LQ PED D
Sbjct: 49 VRPVRDWRKPTTVSIDVIVYAILNVDEKNQVLTTYIWYRQYWTDEFLQWNPEDF-----D 103
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
++T D++W PD L ++ ++ + + V + V+ + + AC ++
Sbjct: 104 NITKLSIPTDSIWVPD--ILINEFVDVGK-SPNIPYVYIRHQGEVQNYKPLQVVTACSLD 160
Query: 120 FQLYPMDIQSCPIYIESFSYSN 141
+P D+Q+C + S+ +++
Sbjct: 161 IYNFPFDVQNCSLTFTSWLHTS 182
>AC092165-3|AAY24103.1| 520|Homo sapiens unknown protein.
Length = 520
Score = 41.5 bits (93), Expect = 0.005
Identities = 37/157 (23%), Positives = 70/157 (44%), Gaps = 9/157 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQL-PEDIFEEGDD 59
+RP R V V + + ++ S+N + +++I W + RL+ P D EG
Sbjct: 44 LRPAERDSDVVNVSLKLTLTNLISLNEREEALTTNVWIEMQWCDYRLRWDPRDY--EGLW 101
Query: 60 HVTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P +W PD L + V + E+ + +V + + + + AC +
Sbjct: 102 VLRVPSTM---VWRPD-IVLENNVDGVFEVA-LYCNVLVSPDGCIYWLPPAIFRSACSIS 156
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKVRFRWS-EAGVTI 155
+P D Q+C + +S +YS ++ + S E G TI
Sbjct: 157 VTYFPFDWQNCSLIFQSQTYSTNEIDLQLSQEDGQTI 193
>Y08417-1|CAA69694.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 40.7 bits (91), Expect = 0.009
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V F + + + ++ ++ +++++Q W++ +L+ D + G
Sbjct: 44 VRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYG-GIHS 102
Query: 61 VTLPPEFFDNLWHPD-PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P E +LW PD F N+ L K V + N TV ++ +C M+
Sbjct: 103 IKVPSE---SLWLPDIVLFENADGRFEGSLMTK---VIVKSNGTVVWTPPASYKSSCTMD 156
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y V
Sbjct: 157 VTFFPFDRQNCSMKFGSWTYDGTMV 181
>X67513-1|CAA47851.1| 423|Homo sapiens nicotinic acetylcholine
receptor beta-3 subunit protein.
Length = 423
Score = 40.7 bits (91), Expect = 0.009
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V F + + + ++ ++ +++++Q W++ +L+ D + G
Sbjct: 9 VRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYG-GIHS 67
Query: 61 VTLPPEFFDNLWHPD-PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P E +LW PD F N+ L K V + N TV ++ +C M+
Sbjct: 68 IKVPSE---SLWLPDIVLFENADGRFEGSLMTK---VIVKSNGTVVWTPPASYKSSCTMD 121
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y V
Sbjct: 122 VTFFPFDRQNCSMKFGSWTYDGTMV 146
>U62438-1|AAB40116.1| 458|Homo sapiens nicotinic acetylcholine
receptor beta3 subunit precursor protein.
Length = 458
Score = 40.7 bits (91), Expect = 0.009
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V F + + + ++ ++ +++++Q W++ +L+ D + G
Sbjct: 44 VRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYG-GIHS 102
Query: 61 VTLPPEFFDNLWHPD-PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P E +LW PD F N+ L K V + N TV ++ +C M+
Sbjct: 103 IKVPSE---SLWLPDIVLFENADGRFEGSLMTK---VIVKSNGTVVWTPPASYKSSCTMD 156
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y V
Sbjct: 157 VTFFPFDRQNCSMKFGSWTYDGTMV 181
>BC069788-1|AAH69788.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 40.7 bits (91), Expect = 0.009
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V F + + + ++ ++ +++++Q W++ +L+ D + G
Sbjct: 44 VRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYG-GIHS 102
Query: 61 VTLPPEFFDNLWHPD-PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P E +LW PD F N+ L K V + N TV ++ +C M+
Sbjct: 103 IKVPSE---SLWLPDIVLFENADGRFEGSLMTK---VIVKSNGTVVWTPPASYKSSCTMD 156
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y V
Sbjct: 157 VTFFPFDRQNCSMKFGSWTYDGTMV 181
>BC069703-1|AAH69703.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 40.7 bits (91), Expect = 0.009
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V F + + + ++ ++ +++++Q W++ +L+ D + G
Sbjct: 44 VRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYG-GIHS 102
Query: 61 VTLPPEFFDNLWHPD-PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P E +LW PD F N+ L K V + N TV ++ +C M+
Sbjct: 103 IKVPSE---SLWLPDIVLFENADGRFEGSLMTK---VIVKSNGTVVWTPPASYKSSCTMD 156
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y V
Sbjct: 157 VTFFPFDRQNCSMKFGSWTYDGTMV 181
>BC069681-1|AAH69681.1| 458|Homo sapiens cholinergic receptor,
nicotinic, beta 3 protein.
Length = 458
Score = 40.7 bits (91), Expect = 0.009
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V F + + + ++ ++ +++++Q W++ +L+ D + G
Sbjct: 44 VRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYG-GIHS 102
Query: 61 VTLPPEFFDNLWHPD-PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P E +LW PD F N+ L K V + N TV ++ +C M+
Sbjct: 103 IKVPSE---SLWLPDIVLFENADGRFEGSLMTK---VIVKSNGTVVWTPPASYKSSCTMD 156
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y V
Sbjct: 157 VTFFPFDRQNCSMKFGSWTYDGTMV 181
>AF140765-1|AAD33063.1| 458|Homo sapiens neuronal acetylcholine
receptor beta-3 subunit precursor protein.
Length = 458
Score = 40.7 bits (91), Expect = 0.009
Identities = 32/145 (22%), Positives = 65/145 (44%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + V F + + + ++ ++ +++++Q W++ +L+ D + G
Sbjct: 44 VRPVLHSNDTIKVYFGLKISQLVDVDEKNQLMTTNVWLKQEWTDHKLRWNPDDYG-GIHS 102
Query: 61 VTLPPEFFDNLWHPD-PYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
+ +P E +LW PD F N+ L K V + N TV ++ +C M+
Sbjct: 103 IKVPSE---SLWLPDIVLFENADGRFEGSLMTK---VIVKSNGTVVWTPPASYKSSCTMD 156
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S++Y V
Sbjct: 157 VTFFPFDRQNCSMKFGSWTYDGTMV 181
>M83712-1|AAA58357.1| 468|Homo sapiens nicotinic receptor alpha 5
subunit protein.
Length = 468
Score = 40.3 bits (90), Expect = 0.012
Identities = 28/144 (19%), Positives = 66/144 (45%), Gaps = 7/144 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP + ++F + + + ++ ++ +++++Q W + +L+ D + G
Sbjct: 62 VRPVEHLNDKIKIKFGLAISQLVDVDEKNQLMTTNVWLKQEWIDVKLRWNPDDY--GGIK 119
Query: 61 VTLPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEF 120
V P D+ W PD ++ + K +V Y N TV ++ + +C ++
Sbjct: 120 VIRVPS--DSSWTPDIVLFDNADGRFEGTSTK--TVIRY-NGTVTWTPPANYKSSCTIDV 174
Query: 121 QLYPMDIQSCPIYIESFSYSNQKV 144
+P D+Q+C + S++Y +V
Sbjct: 175 TFFPFDLQNCSMKFGSWTYDGSQV 198
>AF228449-1|AAF62510.1| 70|Homo sapiens gamma-aminobutyric acid
receptor alpha 5 subunit protein.
Length = 70
Score = 38.7 bits (86), Expect = 0.038
Identities = 21/52 (40%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Query: 250 RADIPPVAYVKALDLWMAGCMMFVFAALGEFVVVKVLDKQ-YQMNKNKAQES 300
R +P VAY A+D ++A C FVF+AL EF V K+ + + KA E+
Sbjct: 15 RNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNYFTKRGWAWDGKKALEA 66
>BC101185-1|AAI01186.1| 374|Homo sapiens HTR3E protein protein.
Length = 374
Score = 38.3 bits (85), Expect = 0.050
Identities = 43/215 (20%), Positives = 86/215 (40%), Gaps = 16/215 (7%)
Query: 70 NLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQMEFQLYPMDIQS 129
NLW PD + + ++ ++ + T K + + +RY M C ++ +P D Q+
Sbjct: 48 NLWLPDIFII--ELMDV-DKTPKGLTAYVSNEGRIRYKKPMKVDSICNLDIFYFPFDQQN 104
Query: 130 CPIYIESFSYSNQKVRFRW-SEAGVTINPELKLLQYHIGQPLRLEETNGYMIDKDGNYSR 188
C + SF Y+ + E + +LQ H G+ E G + SR
Sbjct: 105 CTLTFSSFLYTVDSMLLDMEKEVWEITDASRNILQTH-GE----WELLG-LSKATAKLSR 158
Query: 189 LVVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLDLDAIPGRXXXXXXXXXXXXXXFTG 248
+ + R+ ++I PS +V + SF+L + + G F
Sbjct: 159 VAI----RRRPSLYVINLLVPSGFLVAIDALSFYLPVKS--GNRVPFKITLLLGYNVFLL 212
Query: 249 LRADIPPVAYVKALDLWMAGCMMFVFAALGEFVVV 283
+ +D+ P + + ++ A C+ + +L E + +
Sbjct: 213 MMSDLLPTSGTPLIGVYFALCLSLMVGSLLETIFI 247
>X55019-1|CAA38759.1| 517|Homo sapiens acetylcholine receptor delta
subunit protein.
Length = 517
Score = 37.1 bits (82), Expect = 0.12
Identities = 31/145 (21%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A K + V V ++ + ++ S+ + +++I W+++RL+ + F G+
Sbjct: 42 LRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEF--GNIS 99
Query: 61 VT-LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
V LPP D +W P+ N+ ++++ +V +Y V + +C +
Sbjct: 100 VLRLPP---DMVWLPEIVLENNNDGSF-QISYS-CNVLVYHYGFVYWLPPAIFRSSCPIS 154
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S Y+ +++
Sbjct: 155 VTYFPFDWQNCSLKFSSLKYTAKEI 179
>BC093925-1|AAH93925.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 37.1 bits (82), Expect = 0.12
Identities = 31/145 (21%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A K + V V ++ + ++ S+ + +++I W+++RL+ + F G+
Sbjct: 42 LRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEF--GNIS 99
Query: 61 VT-LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
V LPP D +W P+ N+ ++++ +V +Y V + +C +
Sbjct: 100 VLRLPP---DMVWLPEIVLENNNDGSF-QISYS-CNVLVYHYGFVYWLPPAIFRSSCPIS 154
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S Y+ +++
Sbjct: 155 VTYFPFDWQNCSLKFSSLKYTAKEI 179
>BC093923-1|AAH93923.1| 517|Homo sapiens cholinergic receptor,
nicotinic, delta protein.
Length = 517
Score = 37.1 bits (82), Expect = 0.12
Identities = 31/145 (21%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A K + V V ++ + ++ S+ + +++I W+++RL+ + F G+
Sbjct: 42 LRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEF--GNIS 99
Query: 61 VT-LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
V LPP D +W P+ N+ ++++ +V +Y V + +C +
Sbjct: 100 VLRLPP---DMVWLPEIVLENNNDGSF-QISYS-CNVLVYHYGFVYWLPPAIFRSSCPIS 154
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S Y+ +++
Sbjct: 155 VTYFPFDWQNCSLKFSSLKYTAKEI 179
>AC092165-2|AAY24102.1| 517|Homo sapiens unknown protein.
Length = 517
Score = 37.1 bits (82), Expect = 0.12
Identities = 31/145 (21%), Positives = 68/145 (46%), Gaps = 8/145 (5%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP A K + V V ++ + ++ S+ + +++I W+++RL+ + F G+
Sbjct: 42 LRPVAHKEESVDVALALTLSNLISLKEVEETLTTNVWIEHGWTDNRLKWNAEEF--GNIS 99
Query: 61 VT-LPPEFFDNLWHPDPYFLNSKVTEIAELTHKFSSVTLYRNQTVRYSARMHAIIACQME 119
V LPP D +W P+ N+ ++++ +V +Y V + +C +
Sbjct: 100 VLRLPP---DMVWLPEIVLENNNDGSF-QISYS-CNVLVYHYGFVYWLPPAIFRSSCPIS 154
Query: 120 FQLYPMDIQSCPIYIESFSYSNQKV 144
+P D Q+C + S Y+ +++
Sbjct: 155 VTYFPFDWQNCSLKFSSLKYTAKEI 179
>BC096083-1|AAH96083.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 31.1 bits (67), Expect = 7.6
Identities = 16/83 (19%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q + ++ + + + S+N + +++++Q W++ RL + EG +
Sbjct: 44 IRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRY-EGVNI 102
Query: 61 VTLPPEFFDNLWHPDPYFLNSKV 83
+ +P + +W PD N +
Sbjct: 103 LRIPAK---RIWLPDIVLYNKSL 122
>BC096081-1|AAH96081.1| 198|Homo sapiens CHRNB4 protein protein.
Length = 198
Score = 31.1 bits (67), Expect = 7.6
Identities = 16/83 (19%), Positives = 39/83 (46%), Gaps = 4/83 (4%)
Query: 1 MRPPARKGQPVIVEFSIYVVDVNSINVEDMDFRVDMFIRQTWSESRLQLPEDIFEEGDDH 60
+RP Q + ++ + + + S+N + +++++Q W++ RL + EG +
Sbjct: 44 IRPATSSSQLISIKLQLSLAQLISVNEREQIMTTNVWLKQEWTDYRLTWNSSRY-EGVNI 102
Query: 61 VTLPPEFFDNLWHPDPYFLNSKV 83
+ +P + +W PD N +
Sbjct: 103 LRIPAK---RIWLPDIVLYNKSL 122
Database: human
Posted date: Oct 5, 2007 11:13 AM
Number of letters in database: 73,234,838
Number of sequences in database: 224,733
Lambda K H
0.325 0.139 0.435
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 57,367,516
Number of Sequences: 224733
Number of extensions: 2204945
Number of successful extensions: 8134
Number of sequences better than 10.0: 208
Number of HSP's better than 10.0 without gapping: 103
Number of HSP's successfully gapped in prelim test: 105
Number of HSP's that attempted gapping in prelim test: 7650
Number of HSP's gapped (non-prelim): 301
length of query: 418
length of database: 73,234,838
effective HSP length: 92
effective length of query: 326
effective length of database: 52,559,402
effective search space: 17134365052
effective search space used: 17134365052
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 40 (21.6 bits)
S2: 67 (31.1 bits)
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