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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000839-TA|BGIBMGA000839-PA|IPR001680|WD-40 repeat,
IPR002086|Aldehyde dehydrogenase, IPR011047|Quinonprotein alcohol
dehydrogenase-like, IPR006789|ARP2/3 complex 16 kDa subunit (p16-Arc),
IPR007190|Periodic tryptophan protein-associated region
         (746 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

U56089-1|AAC50905.1|  919|Homo sapiens periodic tryptophan prote...   702   0.0  
U56085-1|AAC50904.1|  919|Homo sapiens periodic tryptophan prote...   702   0.0  
U53346-1|AAB08084.1|  919|Homo sapiens PWP2H protein protein.         702   0.0  
AP001753-1|BAA95553.1|  919|Homo sapiens periodic tryptophan pro...   702   0.0  
AB001517-2|BAA21137.1|  919|Homo sapiens PWP2 protein protein.        702   0.0  
X95263-1|CAA64560.1|  919|Homo sapiens PWP2 protein.                  700   0.0  
BC014988-1|AAH14988.1|  919|Homo sapiens PWP2 periodic tryptopha...   699   0.0  
BC013309-1|AAH13309.1|  919|Homo sapiens PWP2 periodic tryptopha...   699   0.0  
AB209438-1|BAD92675.1|  316|Homo sapiens PWP2 periodic tryptopha...   268   5e-71
BC013997-1|AAH13997.1|  353|Homo sapiens guanine nucleotide bind...   102   5e-21
AF501885-1|AAM15921.1|  353|Homo sapiens guanine nucleotide bind...   102   5e-21
AF300650-1|AAG18444.1|  395|Homo sapiens guanine nucleotide bind...   102   5e-21
AF017656-1|AAC63826.1|  353|Homo sapiens G protein beta 5 subuni...   102   5e-21
BX649632-1|CAI18774.1|  334|Homo sapiens WD repeat domain 5 prot...    93   3e-18
BC001635-1|AAH01635.1|  334|Homo sapiens WD repeat domain 5 prot...    93   3e-18
AK000552-1|BAA91248.1|  334|Homo sapiens protein ( Homo sapiens ...    93   3e-18
AJ011376-1|CAB66159.1|  362|Homo sapiens hypothetical protein pr...    93   3e-18
BC127949-1|AAI27950.1|  314|Homo sapiens similar to hypothetical...    93   4e-18
AL354928-6|CAI39637.1|  314|Homo sapiens WD repeat domain 38 pro...    91   2e-17
CR457279-1|CAG33560.1|  330|Homo sapiens WDR5B protein.                89   4e-17
BC043494-1|AAH43494.1|  330|Homo sapiens WD repeat domain 5B pro...    89   4e-17
AK002149-1|BAA92110.1|  330|Homo sapiens protein ( Homo sapiens ...    89   4e-17
M36429-1|AAA63264.1|  340|Homo sapiens protein ( Human transduci...    89   7e-17
M16514-1|AAA03179.1|  340|Homo sapiens GNB2 protein.                   89   7e-17
CR541729-1|CAG46530.1|  340|Homo sapiens GNB2 protein.                 89   7e-17
BC068003-1|AAH68003.1|  340|Homo sapiens guanine nucleotide bind...    89   7e-17
BC012348-1|AAH12348.1|  340|Homo sapiens guanine nucleotide bind...    89   7e-17
BC010073-1|AAH10073.1|  340|Homo sapiens guanine nucleotide bind...    89   7e-17
AF501883-1|AAM15919.1|  340|Homo sapiens guanine nucleotide bind...    89   7e-17
AF053356-4|AAC78794.1|  340|Homo sapiens GNB2 protein.                 89   7e-17
M16538-1|AAA35922.1|  340|Homo sapiens protein ( Human signal-tr...    87   3e-16
BC000873-1|AAH00873.1|  340|Homo sapiens guanine nucleotide bind...    86   5e-16
AF300648-1|AAG18442.1|  340|Homo sapiens guanine nucleotide bind...    86   5e-16
X95525-1|CAA64777.1|  799|Homo sapiens hTAFII100 protein.              85   9e-16
U80191-1|AAC51215.1|  800|Homo sapiens TFIID subunit TAFII100 pr...    85   9e-16
U75309-1|AAC50902.1|  801|Homo sapiens TBP-associated factor pro...    85   9e-16
BC052268-1|AAH52268.2|  800|Homo sapiens TAF5 RNA polymerase II,...    85   9e-16
AL591408-4|CAI16747.1|  800|Homo sapiens TAF5 RNA polymerase II,...    85   9e-16
AK223615-1|BAD97335.1|  803|Homo sapiens Transcription initiatio...    85   9e-16
BC036377-1|AAH36377.1|  415|Homo sapiens WD repeat domain 69 pro...    85   1e-15
AK098821-1|BAC05425.1|  415|Homo sapiens protein ( Homo sapiens ...    85   1e-15
AK097409-1|BAC05039.1|  415|Homo sapiens protein ( Homo sapiens ...    85   1e-15
AC073065-2|AAX93215.1|  415|Homo sapiens unknown protein.              85   1e-15
X04526-2|CAA28207.1|  340|Homo sapiens protein ( Human liver mRN...    84   2e-15
M36430-1|AAA63265.1|  247|Homo sapiens protein ( Human transduci...    84   2e-15
CR456784-1|CAG33065.1|  340|Homo sapiens GNB1 protein.                 84   2e-15
BT007305-1|AAP35969.1|  340|Homo sapiens guanine nucleotide bind...    84   2e-15
BC008991-1|AAH08991.1|  340|Homo sapiens guanine nucleotide bind...    84   2e-15
BC005888-1|AAH05888.1|  340|Homo sapiens guanine nucleotide bind...    84   2e-15
BC004186-1|AAH04186.1|  340|Homo sapiens guanine nucleotide bind...    84   2e-15
AL109917-5|CAI95654.1|  340|Homo sapiens guanine nucleotide bind...    84   2e-15
AL031282-15|CAI20051.1|  197|Homo sapiens guanine nucleotide bin...    84   2e-15
AL031282-2|CAI20029.1|  340|Homo sapiens guanine nucleotide bind...    84   2e-15
AF501882-1|AAM15918.1|  340|Homo sapiens guanine nucleotide bind...    84   2e-15
AF070603-1|AAC28655.1|  207|Homo sapiens beta-subunit signal tra...    84   2e-15
AF052432-1|AAC09328.1|  655|Homo sapiens katanin p80 subunit pro...    82   6e-15
BC018698-1|AAH18698.1|  504|Homo sapiens PRP19/PSO4 pre-mRNA pro...    82   8e-15
BC018665-1|AAH18665.1|  504|Homo sapiens PRP19/PSO4 pre-mRNA pro...    82   8e-15
BC008719-1|AAH08719.1|  504|Homo sapiens PRP19/PSO4 pre-mRNA pro...    82   8e-15
AJ131186-1|CAB51857.1|  504|Homo sapiens nuclear matrix protein ...    82   8e-15
AL121990-7|CAI22015.1|  589|Homo sapiens TAF5-like RNA polymeras...    81   1e-14
AJ009770-1|CAA08816.1|  260|Homo sapiens putative transcription ...    81   1e-14
AF069736-1|AAC39906.1|  589|Homo sapiens PCAF associated factor ...    81   1e-14
U82756-1|AAC02261.1|  520|Homo sapiens WD splicing factor Hprp4p...    81   2e-14
CR457105-1|CAG33386.1|  521|Homo sapiens PRPF4 protein.                81   2e-14
BC007424-1|AAH07424.1|  521|Homo sapiens PRP4 pre-mRNA processin...    81   2e-14
BC001588-1|AAH01588.1|  522|Homo sapiens PRP4 pre-mRNA processin...    81   2e-14
AY572489-1|AAS78572.1|  521|Homo sapiens 60 kDa U4/U6 snRNP-spec...    81   2e-14
AL449305-8|CAI10969.1|  521|Homo sapiens PRP4 pre-mRNA processin...    81   2e-14
AL449305-7|CAI10968.1|  522|Homo sapiens PRP4 pre-mRNA processin...    81   2e-14
AF016369-1|AAC51925.1|  522|Homo sapiens U4/U6 small nuclear rib...    81   2e-14
AF001687-1|AAB87640.1|  521|Homo sapiens U4/U6 snRNP 60 kDa prot...    81   2e-14
AB209797-1|BAD93034.1|  537|Homo sapiens PRPF4 protein variant p...    81   2e-14
BT009800-1|AAP88802.1|  340|Homo sapiens guanine nucleotide bind...    80   3e-14
BC002454-1|AAH02454.1|  340|Homo sapiens guanine nucleotide bind...    80   3e-14
BC000115-1|AAH00115.1|  340|Homo sapiens guanine nucleotide bind...    80   3e-14
CR456762-1|CAG33043.1|  655|Homo sapiens KATNB1 protein.               79   4e-14
BT007022-1|AAP35668.1|  655|Homo sapiens katanin p80 (WD40-conta...    79   4e-14
BC001353-1|AAH01353.1|  655|Homo sapiens katanin p80 (WD repeat ...    79   4e-14
Y12050-1|CAA72779.1|  340|Homo sapiens guanine nucleotide-bindin...    79   6e-14
U47924-5|AAB51313.1|  340|Homo sapiens G-protein beta-3 chain pr...    79   6e-14
M31328-1|AAA52582.1|  340|Homo sapiens GNB3 protein.                   79   6e-14
AY631872-1|AAT38116.1|  340|Homo sapiens guanine nucleotide bind...    79   6e-14
AF501884-1|AAM15920.1|  340|Homo sapiens guanine nucleotide bind...    79   6e-14
AB209283-1|BAD92520.1|  327|Homo sapiens guanine nucleotide-bind...    79   6e-14
CR457333-1|CAG33614.1|  305|Homo sapiens REC14 protein.                75   7e-13
M24194-1|AAA59626.1|  317|Homo sapiens MHC B complex protein 12....    74   2e-12
CR541909-1|CAG46707.1|  317|Homo sapiens GNB2L1 protein.               74   2e-12
CR456978-1|CAG33259.1|  317|Homo sapiens GNB2L1 protein.               74   2e-12
BC117246-1|AAI17247.1|  707|Homo sapiens F-box and WD repeat dom...    74   2e-12
BC117244-1|AAI17245.1|  707|Homo sapiens F-box and WD repeat dom...    74   2e-12
BC114618-1|AAI14619.1|  332|Homo sapiens GNB1 protein protein.         74   2e-12
BC037320-1|AAH37320.1|  621|Homo sapiens FBXW7 protein protein.        74   2e-12
BC032006-1|AAH32006.1|  317|Homo sapiens guanine nucleotide bind...    74   2e-12
BC021993-1|AAH21993.1|  317|Homo sapiens guanine nucleotide bind...    74   2e-12
BC019362-1|AAH19362.1|  317|Homo sapiens guanine nucleotide bind...    74   2e-12
BC019093-1|AAH19093.1|  317|Homo sapiens guanine nucleotide bind...    74   2e-12
BC017287-1|AAH17287.1|  317|Homo sapiens guanine nucleotide bind...    74   2e-12
BC014788-1|AAH14788.1|  317|Homo sapiens guanine nucleotide bind...    74   2e-12
BC014256-1|AAH14256.1|  317|Homo sapiens guanine nucleotide bind...    74   2e-12
BC010119-1|AAH10119.1|  317|Homo sapiens guanine nucleotide bind...    74   2e-12
BC000366-1|AAH00366.1|  317|Homo sapiens guanine nucleotide bind...    74   2e-12
BC000214-1|AAH00214.1|  317|Homo sapiens guanine nucleotide bind...    74   2e-12
AY159316-1|AAO21313.1|  347|Homo sapiens lung cancer oncogene 7 ...    74   2e-12
AY049984-1|AAL07271.1|  707|Homo sapiens F-box protein CDC4 prot...    74   2e-12
AY033553-1|AAK57547.1|  627|Homo sapiens F-box protein FBW7 prot...    74   2e-12
AY008274-1|AAG16640.1|  589|Homo sapiens F-box protein SEL10 pro...    74   2e-12
AK223449-1|BAD97169.1|  627|Homo sapiens F-box protein FBW7 isof...    74   2e-12
AK001933-1|BAA91986.1|  553|Homo sapiens protein ( Homo sapiens ...    74   2e-12
AF411972-1|AAL06291.1|  627|Homo sapiens archipelago beta form p...    74   2e-12
AF411971-1|AAL06290.1|  707|Homo sapiens archipelago alpha form ...    74   2e-12
AF383178-1|AAK60269.1|  561|Homo sapiens F-box protein FBX30 pro...    74   2e-12
AB209725-1|BAD92962.1|  624|Homo sapiens F-box protein FBW7 isof...    74   2e-12
BC010080-1|AAH10080.1|  305|Homo sapiens WD repeat domain 61 pro...    73   3e-12
AK024754-1|BAB14986.1|  305|Homo sapiens protein ( Homo sapiens ...    73   3e-12
AF309553-1|AAG31639.1|  305|Homo sapiens meiotic recombination p...    73   3e-12
AF100786-1|AAP97225.1|  305|Homo sapiens G protein beta subunit-...    73   3e-12
AK222488-1|BAD96208.1|  317|Homo sapiens guanine nucleotide bind...    73   4e-12
BC015887-1|AAH15887.1|  404|Homo sapiens WD repeat and SOCS box-...    72   7e-12
BC007417-1|AAH07417.2|  396|Homo sapiens WDR51A protein protein.       72   7e-12
AF229181-1|AAF71302.1|  404|Homo sapiens CS box-containing WD pr...    72   7e-12
AF163324-1|AAF80478.1|  404|Homo sapiens WSB-2 protein.                72   7e-12
EF011619-1|ABK41109.1|  478|Homo sapiens CDW9/WDR51B protein.          72   9e-12
BC026080-1|AAH26080.1|  478|Homo sapiens WD repeat domain 51B pr...    72   9e-12
AK074772-1|BAC11198.1|  478|Homo sapiens protein ( Homo sapiens ...    72   9e-12
AK075289-1|BAC11525.1|  407|Homo sapiens protein ( Homo sapiens ...    71   1e-11
BC113421-1|AAI13422.1|  514|Homo sapiens transducin (beta)-like ...    71   2e-11
AK022956-1|BAB14331.1|  514|Homo sapiens protein ( Homo sapiens ...    71   2e-11
AF314544-1|AAK00301.1|  514|Homo sapiens nuclear receptor co-rep...    71   2e-11
BC028628-1|AAH28628.1|  375|Homo sapiens WDR71 protein protein.        71   2e-11
AF087895-1|AAP97194.1|  375|Homo sapiens G-16 protein.                 71   2e-11
BC119693-1|AAI19694.1|  441|Homo sapiens WDR51A protein protein.       70   3e-11
BC021541-1|AAH21541.1|  392|Homo sapiens WD repeat domain 71 pro...    70   3e-11
BC006142-1|AAH06142.2|  392|Homo sapiens WD repeat domain 71 pro...    70   3e-11
AK021910-1|BAB13933.1|  392|Homo sapiens protein ( Homo sapiens ...    70   3e-11
AF268193-1|AAG44736.1|  514|Homo sapiens IRA1 protein.                 70   3e-11
BC119692-1|AAI19693.1|  407|Homo sapiens WD repeat domain 51A pr...    69   5e-11
BC110877-1|AAI10878.1|  359|Homo sapiens WDR51A protein protein.       69   5e-11
BC015920-1|AAH15920.1|  297|Homo sapiens GNB3 protein protein.         69   5e-11
AF208838-1|AAL34973.1|  410|Homo sapiens Miller-Dieker lissencep...    69   8e-11
U72342-1|AAC51111.1|  410|Homo sapiens platelet activating facto...    68   1e-10
L13386-1|AAA02881.1|  410|Homo sapiens Miller-Dieker lissencepha...    68   1e-10
L13385-1|AAA02880.1|  410|Homo sapiens Miller-Dieker lissencepha...    68   1e-10
BC064638-1|AAH64638.1|  410|Homo sapiens platelet-activating fac...    68   1e-10
AF400434-1|AAK92483.1|  410|Homo sapiens platelet-activating fac...    68   1e-10
AF208837-1|AAL34972.1|  410|Homo sapiens Miller-Dieker lissencep...    68   1e-10
AK074217-1|BAB85020.1|  506|Homo sapiens protein ( Homo sapiens ...    67   2e-10
BC021110-1|AAH21110.1|  421|Homo sapiens WD repeat and SOCS box-...    67   2e-10
AF112205-1|AAF17193.1|  421|Homo sapiens WSB-1 protein protein.        67   2e-10
AF072880-1|AAD28808.1|  421|Homo sapiens SOCS box-containing WD ...    67   2e-10
AF069313-1|AAD20954.2|  421|Homo sapiens WSB1 protein protein.         67   2e-10
Y12781-1|CAA73319.1|  577|Homo sapiens transducin (beta) like 1 ...    66   3e-10
BC052304-1|AAH52304.1|  577|Homo sapiens transducin (beta)-like ...    66   3e-10
BC032708-1|AAH32708.1|  526|Homo sapiens TBL1X protein protein.        66   3e-10
AY336089-1|AAR24619.1|  271|Homo sapiens proliferation-inducing ...    66   3e-10
AF106683-1|AAD43036.1|  421|Homo sapiens WSB-1 protein.                66   3e-10
AB209608-1|BAD92845.1|  540|Homo sapiens transducin beta-like 1X...    66   3e-10
AK222501-1|BAD96221.1|  392|Homo sapiens hypothetical protein FL...    66   4e-10
AK074917-1|BAC11291.1|  421|Homo sapiens protein ( Homo sapiens ...    66   4e-10
L13387-1|AAA02882.1|  288|Homo sapiens Miller-Dieker lissencepha...    66   6e-10
AK127882-1|BAC87175.1|  369|Homo sapiens protein ( Homo sapiens ...    66   6e-10
U05340-1|AAA19017.1|  499|Homo sapiens p55CDC protein.                 64   1e-09
DQ473545-1|ABE96834.1|  499|Homo sapiens CDC20 cell division cyc...    64   1e-09
BT007388-1|AAP36052.1|  499|Homo sapiens CDC20 cell division cyc...    64   1e-09
BC130473-1|AAI30474.1|  522|Homo sapiens transducin (beta)-like ...    64   1e-09
BC130471-1|AAI30472.1|  522|Homo sapiens transducin (beta)-like ...    64   1e-09
BC110321-1|AAI10322.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC106004-1|AAI06005.1|  514|Homo sapiens pleiotropic regulator 1...    64   1e-09
BC031294-1|AAH31294.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC024257-1|AAH24257.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC020786-1|AAH20786.1|  505|Homo sapiens PLRG1 protein protein.        64   1e-09
BC015998-1|AAH15998.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC013303-1|AAH13303.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC012827-1|AAH12827.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC012803-1|AAH12803.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC012075-1|AAH12075.1|  485|Homo sapiens notchless homolog 1 (Dr...    64   1e-09
BC010044-1|AAH10044.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC009426-1|AAH09426.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC009425-1|AAH09425.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC006272-1|AAH06272.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC002884-1|AAH02884.2|  484|Homo sapiens NLE1 protein protein.         64   1e-09
BC001088-1|AAH01088.1|  499|Homo sapiens cell division cycle 20 ...    64   1e-09
BC000624-1|AAH00624.1|  499|Homo sapiens CDC20 protein protein.        64   1e-09
AL139289-3|CAB92757.1|  499|Homo sapiens CDC20 cell division cyc...    64   1e-09
AK001320-1|BAA91621.1|  485|Homo sapiens protein ( Homo sapiens ...    64   1e-09
AF332222-1|AAK13474.1|  522|Homo sapiens transducin beta-like 1 ...    64   1e-09
AF332221-1|AAK13473.1|  522|Homo sapiens transducin beta-like 1 ...    64   1e-09
AF332220-1|AAK13472.1|  522|Homo sapiens transducin beta-like 1 ...    64   1e-09
AF099644-1|AAD16405.1|  499|Homo sapiens cell cycle protein CDC2...    64   1e-09
AF044333-1|AAD09407.1|  514|Homo sapiens pleiotropic regulator 1...    64   1e-09
AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein.              64   1e-09
AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein.               64   1e-09
BC021905-1|AAH21905.1|  896|Homo sapiens Unknown (protein for IM...    64   2e-09
AL450327-2|CAH70884.1| 1821|Homo sapiens protein ( Human DNA seq...    64   2e-09
AL356776-2|CAI14406.1| 1821|Homo sapiens protein ( Human DNA seq...    64   2e-09
AL121993-4|CAI22739.1|  943|Homo sapiens WD repeat domain 3 prot...    64   2e-09
AK057039-1|BAB71353.1|  912|Homo sapiens protein ( Homo sapiens ...    64   2e-09
AJ303102-1|CAC83118.1| 1821|Homo sapiens WD repeat domain 11 pro...    64   2e-09
AF083217-1|AAD45865.1|  943|Homo sapiens WD repeat protein WDR3 ...    64   2e-09
BC025392-1|AAH25392.1|  620|Homo sapiens WD repeat domain 16 pro...    64   2e-09
AK222576-1|BAD96296.1|  421|Homo sapiens WD SOCS-box protein 1 i...    64   2e-09
AK094847-1|BAC04435.1|  630|Homo sapiens protein ( Homo sapiens ...    64   2e-09
AK074435-1|BAB85083.1|  412|Homo sapiens protein ( Homo sapiens ...    64   2e-09
AB065281-1|BAB83743.1|  620|Homo sapiens WDR16 protein.                64   2e-09
X70476-1|CAA49900.1|  906|Homo sapiens subunit of coatomer compl...    63   3e-09
BC000326-1|AAH00326.1|  906|Homo sapiens coatomer protein comple...    63   3e-09
AF127799-1|AAP97249.1|  305|Homo sapiens G protein beta subunit-...    63   4e-09
X96586-1|CAA65405.1|  917|Homo sapiens FAN protein protein.            62   7e-09
BC041124-1|AAH41124.1|  917|Homo sapiens neutral sphingomyelinas...    62   7e-09
U63810-1|AAC24948.1|  339|Homo sapiens WD40 protein Ciao 1 protein.    62   9e-09
EF011618-1|ABK41108.1|  339|Homo sapiens CDW8/WDR39 protein.           62   9e-09
CR456802-1|CAG33083.1|  339|Homo sapiens CIAO1 protein.                62   9e-09
BC032812-1|AAH32812.1|  339|Homo sapiens cytosolic iron-sulfur p...    62   9e-09
BC026353-1|AAH26353.1|  677|Homo sapiens WD repeat domain 48 pro...    62   9e-09
BC001395-1|AAH01395.1|  339|Homo sapiens cytosolic iron-sulfur p...    62   9e-09
AK223257-1|BAD96977.1|  339|Homo sapiens WD40 protein Ciao1 vari...    62   9e-09
AF492460-1|AAN64030.1| 1322|Homo sapiens WD repeat 17 protein.         62   9e-09
AF468833-1|AAL78650.1|  677|Homo sapiens WD repeat endosomal pro...    62   9e-09
AC004020-1|AAC23493.1|  339|Homo sapiens Unknown gene product pr...    62   9e-09
AB053276-1|BAB69430.1|  348|Homo sapiens TUWD12 protein.               62   9e-09
AB053266-1|BAB69057.1|  348|Homo sapiens TUWD12 protein.               62   9e-09
AB040882-1|BAA95973.2|  680|Homo sapiens KIAA1449 protein protein.     62   9e-09
EF011621-1|ABK41111.1|  357|Homo sapiens CDW11/WDR57 protein.          60   2e-08
BC001494-1|AAH01494.1|  357|Homo sapiens WD repeat domain 57 (U5...    60   2e-08
AL451070-1|CAH71848.1|  357|Homo sapiens WD repeat domain 57 (U5...    60   2e-08
AF490390-1|AAM97147.1|  631|Homo sapiens sperm-associated WD rep...    60   2e-08
AF310672-1|AAM63956.1|  631|Homo sapiens PF20 variant 1a protein.      60   2e-08
AF090988-1|AAC69625.1|  357|Homo sapiens U5 snRNP-specific 40 kD...    60   2e-08
BC111490-1|AAI11491.1|  768|Homo sapiens BRWD3 protein protein.        60   3e-08
BC025379-1|AAH25379.1|  571|Homo sapiens SPAG16 protein protein.       60   3e-08
AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repe...    60   3e-08
AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repe...    60   3e-08
AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repe...    60   3e-08
AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repe...    60   3e-08
AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repe...    60   3e-08
AK093221-1|BAC04099.1|  649|Homo sapiens protein ( Homo sapiens ...    59   5e-08
EF011613-1|ABK41103.1|  513|Homo sapiens CDW3/SMU1 protein.            59   7e-08
BC110654-1|AAI10655.1|  513|Homo sapiens smu-1 suppressor of mec...    59   7e-08
BC026213-1|AAH26213.1|  529|Homo sapiens F-box and WD repeat dom...    59   7e-08
BC002876-1|AAH02876.1|  513|Homo sapiens smu-1 suppressor of mec...    59   7e-08
AL162590-6|CAI15554.1|  513|Homo sapiens smu-1 suppressor of mec...    59   7e-08
AK001667-1|BAA91822.1|  513|Homo sapiens protein ( Homo sapiens ...    59   7e-08
AF176022-1|AAF04528.1|  542|Homo sapiens F-box protein Fbw1b pro...    59   7e-08
AB033281-1|BAA92331.1|  542|Homo sapiens F-box and WD-repeats pr...    59   7e-08
AB033280-1|BAA92330.1|  529|Homo sapiens F-box and WD-repeats pr...    59   7e-08
AB033279-1|BAA92329.1|  508|Homo sapiens F-box and WD-repeats pr...    59   7e-08
AB014596-1|BAA31671.1|  550|Homo sapiens KIAA0696 protein protein.     59   7e-08
BC023662-1|AAH23662.2|  475|Homo sapiens RRP9, small subunit (SS...    58   9e-08
BC010048-1|AAH10048.1|  475|Homo sapiens RRP9, small subunit (SS...    58   9e-08
BC009879-1|AAH09879.1|  475|Homo sapiens RRP9, small subunit (SS...    58   9e-08
BC001113-1|AAH01113.1|  475|Homo sapiens RRP9, small subunit (SS...    58   9e-08
AJ001340-1|CAA04687.1|  475|Homo sapiens U3 snoRNP associated 55...    58   9e-08
AB209111-1|BAD92348.1|  487|Homo sapiens Notchless gene homolog ...    58   9e-08
BC031227-1|AAH31227.2|  452|Homo sapiens WDR88 protein protein.        58   1e-07
BC027605-1|AAH27605.1|  660|Homo sapiens neural precursor cell e...    58   1e-07
BC020799-1|AAH20799.1|  532|Homo sapiens Unknown (protein for IM...    58   1e-07
AK131444-1|BAD18589.1|  472|Homo sapiens protein ( Homo sapiens ...    58   1e-07
DQ120664-1|ABB92447.1|  456|Homo sapiens rcCDC20 protein.              58   2e-07
BC133025-1|AAI33026.1|  951|Homo sapiens WD repeat domain 36 pro...    58   2e-07
AK095312-1|BAC04527.1|  895|Homo sapiens protein ( Homo sapiens ...    58   2e-07
AF385437-1|AAM43838.1|  951|Homo sapiens T-cell activation WD re...    58   2e-07
U86136-1|AAC51107.1| 2627|Homo sapiens telomerase-associated pro...    57   3e-07
BC126107-1|AAI26108.1| 2627|Homo sapiens telomerase-associated p...    57   3e-07
BC035409-1|AAH35409.1|  808|Homo sapiens transducin (beta)-like ...    57   3e-07
BC014007-1|AAH14007.1|  808|Homo sapiens TBL3 protein protein.         57   3e-07
BC010231-1|AAH10231.1|  808|Homo sapiens transducin (beta)-like ...    57   3e-07
BC007620-1|AAH07620.1|  570|Homo sapiens TBL3 protein protein.         57   3e-07
AF070597-1|AAC28652.1|  127|Homo sapiens beta-subunit signal tra...    57   3e-07
AB209669-1|BAD92906.1| 1903|Homo sapiens Telomerase protein comp...    57   3e-07
AB209173-1|BAD92410.1|  832|Homo sapiens transducin beta-like 3 ...    57   3e-07
AB209201-1|BAD92438.1|  466|Homo sapiens WD repeat-containing pr...    56   5e-07
M99438-1|AAA61194.1|  772|Homo sapiens transducin-like enhancer ...    55   8e-07
BC012352-1|AAH12352.1|  366|Homo sapiens WDR31 protein protein.        55   8e-07
AL449305-1|CAI10961.1|  367|Homo sapiens WD repeat domain 31 pro...    55   8e-07
AL137066-1|CAH70096.1|  367|Homo sapiens WD repeat domain 31 pro...    55   8e-07
AK093240-1|BAC04106.1|  367|Homo sapiens protein ( Homo sapiens ...    55   8e-07
BC028364-1|AAH28364.1| 1061|Homo sapiens FBXW10 protein protein.       54   1e-06
AY729024-1|AAU43731.1| 1052|Homo sapiens ubiquitin ligase specif...    54   1e-06
AB209899-1|BAD93136.1|  967|Homo sapiens Hypothetical protein DK...    54   1e-06
AJ243009-1|CAB55585.1| 1248|Homo sapiens apoptotic protease acti...    54   2e-06
BC063041-1|AAH63041.1| 1129|Homo sapiens WD repeat and HMG-box D...    54   2e-06
BC043349-1|AAH43349.1|  612|Homo sapiens WDHD1 protein protein.        54   2e-06
BC005040-1|AAH05040.1|  613|Homo sapiens Unknown (protein for IM...    54   2e-06
BC000622-1|AAH00622.1|  613|Homo sapiens WDHD1 protein protein.        54   2e-06
AM177180-1|CAJ45484.1| 1670|Homo sapiens kinesin-like protein KI...    54   2e-06
AJ243048-1|CAB55588.1| 1248|Homo sapiens apoptotic protease acti...    54   2e-06
AJ243011-1|CAB55587.1| 1205|Homo sapiens protease activating fac...    54   2e-06
AJ243010-1|CAB55586.1| 1205|Homo sapiens apoptotic protease acti...    54   2e-06
AJ243008-1|CAB55584.1| 1205|Homo sapiens apoptotic protease acti...    54   2e-06
AJ243007-1|CAB55583.1| 1205|Homo sapiens apoptotic protease acti...    54   2e-06
AJ243005-1|CAB55581.1| 1205|Homo sapiens apoptotic protease acti...    54   2e-06
AJ243004-1|CAB55580.1| 1205|Homo sapiens apoptotic protease acti...    54   2e-06
AJ243003-1|CAB55579.1| 1205|Homo sapiens apoptotic protease acti...    54   2e-06
AJ006266-1|CAA06932.1| 1129|Homo sapiens AND-1 protein protein.        54   2e-06
AF149794-1|AAD34016.1| 1248|Homo sapiens apoptotic protease acti...    54   2e-06
AF134397-1|AAD38344.1| 1237|Homo sapiens apoptotic protease acti...    54   2e-06
AF013263-1|AAC51678.1| 1194|Homo sapiens apoptotic protease acti...    54   2e-06
AB007873-1|BAA24843.2| 1237|Homo sapiens KIAA0413 protein.             54   2e-06
U39067-1|AAC97144.1|  325|Homo sapiens translation initiation fa...    53   3e-06
U36764-1|AAC50224.1|  325|Homo sapiens TGF-beta receptor interac...    53   3e-06
L02547-1|AAA35691.1|  431|Homo sapiens cleavage stimulation fact...    53   3e-06
BT019597-1|AAV38404.1|  325|Homo sapiens eukaryotic translation ...    53   3e-06
BT007138-1|AAP35802.1|  431|Homo sapiens cleavage stimulation fa...    53   3e-06
BC007425-1|AAH07425.1|  431|Homo sapiens cleavage stimulation fa...    53   3e-06
BC003140-1|AAH03140.1|  325|Homo sapiens eukaryotic translation ...    53   3e-06
BC001011-1|AAH01011.1|  431|Homo sapiens cleavage stimulation fa...    53   3e-06
BC000413-1|AAH00413.1|  325|Homo sapiens eukaryotic translation ...    53   3e-06
AL121991-4|CAI22322.1|  325|Homo sapiens eukaryotic translation ...    53   3e-06
AL121914-12|CAI19328.1|  431|Homo sapiens cleavage stimulation f...    53   3e-06
AL049795-10|CAI22061.1|  325|Homo sapiens eukaryotic translation...    53   3e-06
AK223195-1|BAD96915.1|  315|Homo sapiens mitogen-activated prote...    53   3e-06
AK222483-1|BAD96203.1|  325|Homo sapiens eukaryotic translation ...    53   3e-06
M99436-1|AAA61193.1|  743|Homo sapiens transducin-like enhancer ...    53   4e-06
BC017364-1|AAH17364.1|  743|Homo sapiens transducin-like enhance...    53   4e-06
BC012938-1|AAH12938.1|  446|Homo sapiens TBL2 protein protein.         53   4e-06
BC005870-1|AAH05870.1|  315|Homo sapiens mitogen-activated prote...    53   4e-06
AY583459-1|AAS90945.1|  764|Homo sapiens transducin-like enhance...    53   4e-06
AY358518-1|AAQ88882.1|  447|Homo sapiens TBL2 protein.                 53   4e-06
AK074619-1|BAC11093.1|  447|Homo sapiens protein ( Homo sapiens ...    53   4e-06
AJ243006-1|CAB55582.1| 1205|Homo sapiens apoptotic protease acti...    53   4e-06
AF097485-1|AAF06824.1|  447|Homo sapiens transducin beta-like 2 ...    53   4e-06
AF097484-1|AAF06823.1|  447|Homo sapiens transducin beta-like 2 ...    53   4e-06
AF056183-1|AAD28083.1|  426|Homo sapiens WS beta-transducin repe...    53   4e-06
AC007766-2|AAD38075.1|  553|Homo sapiens TLE2_HUMAN [AA 191- 743...    53   4e-06
M99439-1|AAA61195.1|  448|Homo sapiens transducin-like enhancer ...    52   6e-06
BC059405-1|AAH59405.2|  805|Homo sapiens TLE4 protein protein.         52   6e-06
BC045650-1|AAH45650.1|  704|Homo sapiens TLE4 protein protein.         52   6e-06
BC043247-1|AAH43247.1|  767|Homo sapiens TLE3 protein protein.         52   6e-06
BC041831-1|AAH41831.1|  772|Homo sapiens TLE3 protein protein.         52   6e-06
AY583460-1|AAS90946.1|  767|Homo sapiens transducin-like enhance...    52   6e-06
AL445252-3|CAI13644.1|  764|Homo sapiens transducin-like enhance...    52   6e-06
AL358975-3|CAI13734.1|  764|Homo sapiens transducin-like enhance...    52   6e-06
AL353813-5|CAI41315.1|  764|Homo sapiens transducin-like enhance...    52   6e-06
AB046767-1|BAB13373.1|  863|Homo sapiens KIAA1547 protein protein.     52   6e-06
AB033087-1|BAA86575.1|  787|Homo sapiens KIAA1261 protein protein.     52   6e-06
U88871-1|AAC51238.1|  323|Homo sapiens HsPex7p protein.                52   7e-06
U76560-1|AAB50556.1|  323|Homo sapiens peroxisome targeting sign...    52   7e-06
CR542076-1|CAG46873.1|  323|Homo sapiens PEX7 protein.                 52   7e-06
CR542054-1|CAG46851.1|  323|Homo sapiens PEX7 protein.                 52   7e-06
BT020045-1|AAV38848.1|  350|Homo sapiens unr-interacting protein...    52   7e-06
BT020044-1|AAV38847.1|  350|Homo sapiens unr-interacting protein...    52   7e-06
BC117337-1|AAI17338.1|  523|Homo sapiens ATG16L1 protein protein.      52   7e-06
BC107125-1|AAI07126.1|  248|Homo sapiens WDR86 protein protein.        52   7e-06
BC062306-1|AAH62306.1|  350|Homo sapiens serine/threonine kinase...    52   7e-06
BC047921-1|AAH47921.1|  563|Homo sapiens WDR86 protein protein.        52   7e-06
BC006268-1|AAH06268.1|  323|Homo sapiens peroxisomal biogenesis ...    52   7e-06
BC000162-1|AAH00162.1|  350|Homo sapiens serine/threonine kinase...    52   7e-06
AY398617-1|AAR32130.1|  607|Homo sapiens APG16L beta protein.          52   7e-06
AY049776-1|AAL15433.1|  350|Homo sapiens unr-interacting protein...    52   7e-06
AL365223-4|CAI15714.1|  323|Homo sapiens peroxisomal biogenesis ...    52   7e-06
AL121933-2|CAI15471.1|  323|Homo sapiens peroxisomal biogenesis ...    52   7e-06
AJ010025-1|CAB38041.1|  350|Homo sapiens unr-interacting protein...    52   7e-06
AF180814-1|AAF37350.1|  323|Homo sapiens peroxisomal PTS2 recept...    52   7e-06
AC013726-3|AAY14860.1|  523|Homo sapiens unknown protein.              52   7e-06
AB024327-1|BAA75544.1|  350|Homo sapiens WD-40 repeat protein pr...    52   7e-06
M99435-1|AAA61192.1|  770|Homo sapiens transducin-like enhancer ...    52   1e-05
BC015747-1|AAH15747.1|  770|Homo sapiens transducin-like enhance...    52   1e-05
BC010100-1|AAH10100.1|  770|Homo sapiens transducin-like enhance...    52   1e-05
AL365190-2|CAI14977.1|  770|Homo sapiens transducin-like enhance...    52   1e-05
AL353682-1|CAI12595.1|  770|Homo sapiens transducin-like enhance...    52   1e-05
AL163279-2|CAB90452.1| 2295|Homo sapiens homolog to cAMP respons...    52   1e-05
AJ292466-1|CAC44372.1| 2269|Homo sapiens WDR9 protein, form B  p...    52   1e-05
AJ292465-1|CAC44371.1| 2320|Homo sapiens WDR9 protein, form A pr...    52   1e-05
AJ238214-1|CAC37033.2| 2269|Homo sapiens hypothetical protein pr...    52   1e-05
AF145020-1|AAD42075.1|  649|Homo sapiens phospholipase A2 activa...    52   1e-05
AB080587-1|BAD74072.1| 2199|Homo sapiens WD repeat protein WDR9-...    52   1e-05
AB080586-1|BAD74071.1| 2269|Homo sapiens WD repeat protein protein.    52   1e-05
BC030541-1|AAH30541.1|  466|Homo sapiens WD repeat domain 1 prot...    51   1e-05
BC002489-1|AAH02489.1|  606|Homo sapiens WD repeat domain 1 prot...    51   1e-05
AK127024-1|BAC86793.1|  764|Homo sapiens protein ( Homo sapiens ...    51   1e-05
AJ243107-1|CAB56462.1| 1171|Homo sapiens apoptotic protease acti...    51   1e-05
AF020260-1|AAD05045.1|  534|Homo sapiens WDR1 protein protein.         51   1e-05
AF020056-1|AAD05044.1|  606|Homo sapiens WDR1 protein protein.         51   1e-05
AB010427-1|BAA31855.2|  606|Homo sapiens NORI-1 protein.               51   1e-05
AB007918-1|BAA32294.2| 1628|Homo sapiens KIAA0449 protein protein.     51   1e-05
BC029520-1|AAH29520.1|  384|Homo sapiens WDSUB1 protein protein.       51   2e-05
BC000201-1|AAH00201.1|  606|Homo sapiens WD repeat domain 1 prot...    51   2e-05
AK222897-1|BAD96617.1|  606|Homo sapiens WD repeat-containing pr...    51   2e-05
AK222764-1|BAD96484.1|  606|Homo sapiens WD repeat-containing pr...    51   2e-05
AK093494-1|BAC04184.1|  476|Homo sapiens protein ( Homo sapiens ...    51   2e-05
AB209746-1|BAD92983.1|  624|Homo sapiens WD repeat-containing pr...    51   2e-05
AK022525-1|BAB14077.1|  864|Homo sapiens protein ( Homo sapiens ...    50   2e-05
BT007115-1|AAP35779.1|  493|Homo sapiens Fzr1 protein protein.         50   3e-05
BC110334-1|AAI10335.1|  454|Homo sapiens F-box and WD repeat dom...    50   3e-05
BC034604-1|AAH34604.1|  753|Homo sapiens striatin, calmodulin bi...    50   3e-05
BC032551-1|AAH32551.1|  795|Homo sapiens phospholipase A2-activa...    50   3e-05
BC028387-1|AAH28387.1|  569|Homo sapiens WD repeat domain 20 pro...    50   3e-05
BC018738-1|AAH18738.1|  454|Homo sapiens F-box and WD repeat dom...    50   3e-05
BC013413-1|AAH13413.1|  493|Homo sapiens fizzy/cell division cyc...    50   3e-05
BC004910-1|AAH04910.2|  349|Homo sapiens STRN4 protein protein.        50   3e-05
AL356133-3|CAH72641.1|  738|Homo sapiens phospholipase A2-activa...    50   3e-05
AL161911-2|CAI95113.1|  454|Homo sapiens F-box and WD-40 domain ...    50   3e-05
AK223544-1|BAD97264.1|  748|Homo sapiens Hypothetical protein DK...    50   3e-05
AK022484-1|BAB14051.1|  454|Homo sapiens protein ( Homo sapiens ...    50   3e-05
AK002143-1|BAA92105.1|  544|Homo sapiens protein ( Homo sapiens ...    50   3e-05
AJ238243-1|CAB42881.1|  738|Homo sapiens phospholipase A2 activa...    50   3e-05
AF433157-1|AAL28117.1|  404|Homo sapiens CDC20-like 1b protein.        50   3e-05
AF327354-1|AAL56014.1|  572|Homo sapiens DMR protein protein.          50   3e-05
AF212940-1|AAF29527.1|  753|Homo sapiens zinedin protein.              50   3e-05
AF176698-1|AAF13226.1|  422|Homo sapiens F-box protein FBW2 prot...    50   3e-05
AF145024-1|AAP97276.1|  422|Homo sapiens MD6 protein protein.          50   3e-05
AF129531-1|AAF04465.1|  422|Homo sapiens F-box protein Fbw2 prot...    50   3e-05
AF083810-1|AAD52030.1|  493|Homo sapiens fizzy-related protein p...    50   3e-05
AF083395-1|AAD03030.1|  738|Homo sapiens phospholipase A2-activa...    50   3e-05
AF083383-1|AAC64084.1|  310|Homo sapiens 38kDa splicing factor p...    50   3e-05
AC005787-1|AAC62835.1|  493|Homo sapiens R33374_1 protein.             50   3e-05
AB209148-1|BAD92385.1|  439|Homo sapiens WD repeat domain 20 iso...    50   3e-05
AB209003-1|BAD92240.1|  755|Homo sapiens Zinedin variant protein.      50   3e-05
AB033068-1|BAA86556.1|  504|Homo sapiens KIAA1242 protein protein.     50   3e-05
Y14153-1|CAA74572.1|  569|Homo sapiens beta-transducin repeats c...    50   4e-05
BC117291-1|AAI17292.1|  925|Homo sapiens coronin 7 protein.            50   4e-05
BC117289-1|AAI17290.1|  925|Homo sapiens coronin 7 protein.            50   4e-05
BC027994-1|AAH27994.1|  605|Homo sapiens beta-transducin repeat ...    50   4e-05
AL627424-18|CAI41043.1|  569|Homo sapiens beta-transducin repeat...    50   4e-05
AL627424-17|CAI41042.1|  605|Homo sapiens beta-transducin repeat...    50   4e-05
AL445463-3|CAI12964.1|  569|Homo sapiens beta-transducin repeat ...    50   4e-05
AL445463-2|CAI12963.1|  605|Homo sapiens beta-transducin repeat ...    50   4e-05
AL161911-3|CAI95114.1|  208|Homo sapiens F-box and WD-40 domain ...    50   4e-05
AL133387-2|CAH70019.1|  569|Homo sapiens beta-transducin repeat ...    50   4e-05
AL133387-1|CAH70020.1|  605|Homo sapiens beta-transducin repeat ...    50   4e-05
AK131383-1|BAD18534.1|  141|Homo sapiens protein ( Homo sapiens ...    50   4e-05
AK025674-1|BAB15211.1|  925|Homo sapiens protein ( Homo sapiens ...    50   4e-05
AF129530-1|AAF04464.1|  569|Homo sapiens F-box protein Fbw1A pro...    50   4e-05
AF101784-1|AAD08702.1|  605|Homo sapiens b-TRCP variant E3RS-Ika...    50   4e-05
AB013463-1|BAA86955.1|  404|Homo sapiens Fzr2 protein.                 50   4e-05
AB013462-1|BAA86954.1|  496|Homo sapiens Fzr1 protein.                 50   4e-05
L19267-1|AAA35767.1|  553|Homo sapiens protein ( Homo sapiens 59...    49   7e-05
BX538346-1|CAD98141.1|  147|Homo sapiens hypothetical protein pr...    49   7e-05
BC024267-1|AAH24267.1|  594|Homo sapiens TRAF7 protein protein.        48   9e-05
AY569455-1|AAS68363.1|  670|Homo sapiens TRAF7 protein.                48   9e-05
AL121914-11|CAC12718.2|  345|Homo sapiens cleavage stimulation f...    48   1e-04
AK074891-1|BAC11271.1|  242|Homo sapiens protein ( Homo sapiens ...    48   1e-04
BT006798-1|AAP35444.1|  334|Homo sapiens dystrophia myotonica-co...    47   2e-04
BC126114-1|AAI26115.1|  579|Homo sapiens cell division cycle 40 ...    47   2e-04
BC117145-1|AAI17146.1|  579|Homo sapiens cell division cycle 40 ...    47   2e-04
BC019266-1|AAH19266.1|  334|Homo sapiens DMWD protein protein.         47   2e-04
AL671518-2|CAI13322.1|  579|Homo sapiens cell division cycle 40 ...    47   2e-04
AK222721-1|BAD96441.1|  579|Homo sapiens pre-mRNA splicing facto...    47   2e-04
AF102508-1|AAD26624.1|  142|Homo sapiens fizzy-related protein p...    47   2e-04
AF080397-1|AAF20266.1|  493|Homo sapiens fizzy-related protein h...    47   2e-04
AF061241-1|AAC25166.1|  542|Homo sapiens splicing factor hPRP17 ...    47   2e-04
AF038392-1|AAC39730.1|  579|Homo sapiens pre-mRNA splicing facto...    47   2e-04
AF240696-1|AAF82746.1|  275|Homo sapiens WSB1 isoform 2 protein.       47   3e-04
M95627-1|AAA68889.1|  452|Homo sapiens angio-associated migrator...    46   4e-04
CR456755-1|CAG33036.1|  452|Homo sapiens AAMP protein.                 46   4e-04
BC039866-1|AAH39866.2|  434|Homo sapiens angio-associated, migra...    46   4e-04
BC037168-1|AAH37168.1|  502|Homo sapiens WDR48 protein protein.        46   4e-04
BC020244-1|AAH20244.1|  429|Homo sapiens Similar to angio-associ...    46   4e-04
BC001648-1|AAH01648.1|  432|Homo sapiens WD repeat domain 18 pro...    46   6e-04
BC000040-1|AAH00040.2|  432|Homo sapiens WD repeat domain 18 pro...    46   6e-04
AK126622-1|BAC86616.1| 1060|Homo sapiens protein ( Homo sapiens ...    46   6e-04
U20980-1|AAA76737.1|  559|Homo sapiens chromatin assembly factor...    45   9e-04
BC112042-1|AAI12043.1|  597|Homo sapiens WD repeats and SOF1 dom...    45   9e-04
BC101810-1|AAI01811.1|  597|Homo sapiens WD repeats and SOF1 dom...    45   9e-04
BC047572-1|AAH47572.1|  433|Homo sapiens KIF21A protein protein.       45   9e-04
BC032685-1|AAH32685.1|  662|Homo sapiens Unknown (protein for IM...    45   9e-04
BC026067-1|AAH26067.2|  464|Homo sapiens WDSOF1 protein protein.       45   9e-04
BC021218-1|AAH21218.1|  559|Homo sapiens chromatin assembly fact...    45   9e-04
AY368076-1|AAR04774.1| 1674|Homo sapiens kinesin family member 2...    45   9e-04
AP001725-3|BAA95549.1|  559|Homo sapiens chromatin assembly fact...    45   9e-04
AP000694-1|BAA89426.1|  559|Homo sapiens chromatin assembly fact...    45   9e-04
AK074725-1|BAC11163.1|  597|Homo sapiens protein ( Homo sapiens ...    45   9e-04
AK027799-1|BAB55377.1|  597|Homo sapiens protein ( Homo sapiens ...    45   9e-04
AK001874-1|BAA91955.1|  445|Homo sapiens protein ( Homo sapiens ...    45   9e-04
AF450487-1|AAP97680.1| 1662|Homo sapiens kinesin-like protein KI...    45   9e-04
AB051495-1|BAB21799.2| 1657|Homo sapiens KIAA1708 protein.             45   9e-04
EF079890-1|ABN48555.1|  444|Homo sapiens ATG16 autophagy related...    45   0.001
EF079889-1|ABN48554.1|  588|Homo sapiens ATG16 autophagy related...    45   0.001
BX537855-1|CAD97863.1|  974|Homo sapiens hypothetical protein pr...    45   0.001
BC114493-1|AAI14494.1| 1514|Homo sapiens MAPKBP1 protein protein.      45   0.001
BC113983-1|AAI13984.1| 1231|Homo sapiens MAPKBP1 protein protein.      45   0.001
BC071846-1|AAH71846.1|  475|Homo sapiens ATG16L1 protein protein.      45   0.001
BC005226-1|AAH05226.1|  193|Homo sapiens WSB1 protein protein.         45   0.001
AK123876-1|BAC85713.1|  428|Homo sapiens protein ( Homo sapiens ...    45   0.001
AK026330-1|BAB15448.1|  173|Homo sapiens protein ( Homo sapiens ...    45   0.001
AF106684-1|AAD43037.1|  219|Homo sapiens WSB-1 isoform protein.        45   0.001
AB011168-1|BAA25522.2| 1531|Homo sapiens KIAA0596 protein protein.     45   0.001
X96425-1|CAA65285.1|   35|Homo sapiens ORF protein.                    44   0.001
U24105-1|AAB70879.1| 1224|Homo sapiens coatomer protein protein.       44   0.001
BC038447-1|AAH38447.1| 1233|Homo sapiens COPA protein protein.         44   0.001
AY736034-1|AAU50678.1|  478|Homo sapiens F-box and WD-40 repeat ...    44   0.001
AL513282-3|CAI12455.1| 1233|Homo sapiens coatomer protein comple...    44   0.001
AL513282-2|CAI12454.1| 1224|Homo sapiens coatomer protein comple...    44   0.001
AL445230-2|CAI15005.1| 1224|Homo sapiens coatomer protein comple...    44   0.001
AL445230-1|CAI15004.1| 1233|Homo sapiens coatomer protein comple...    44   0.001
EF011612-1|ABK41102.1|  514|Homo sapiens CDW2/WDR26 protein.           44   0.002
BC068499-1|AAH68499.1|  351|Homo sapiens THO complex 3 protein.        44   0.002
BC068485-1|AAH68485.1|  383|Homo sapiens WD repeat domain 55 pro...    44   0.002
BC066325-1|AAH66325.1|  327|Homo sapiens THOC3 protein protein.        44   0.002
BC063817-1|AAH63817.1|  404|Homo sapiens WDR26 protein protein.        44   0.002
BC052301-1|AAH52301.2|  514|Homo sapiens WD repeat domain 26 pro...    44   0.002
BC052292-1|AAH52292.1|  326|Homo sapiens GBL protein protein.          44   0.002
BC031471-1|AAH31471.2|  373|Homo sapiens WDR26 protein protein.        44   0.002
BC020499-1|AAH20499.1|  327|Homo sapiens GBL protein protein.          44   0.002
BC017119-1|AAH17119.1|  326|Homo sapiens G protein beta subunit-...    44   0.002
BC006849-1|AAH06849.1|  351|Homo sapiens THO complex 3 protein.        44   0.002
BC001313-1|AAH01313.1|  326|Homo sapiens G protein beta subunit-...    44   0.002
AY304473-1|AAQ74770.1|  514|Homo sapiens WD40 repeat protein 26 ...    44   0.002
AY221751-1|AAO67709.1|  498|Homo sapiens myocardial ischemic pre...    44   0.002
AK131467-1|BAD18612.1|  419|Homo sapiens protein ( Homo sapiens ...    44   0.002

>U56089-1|AAC50905.1|  919|Homo sapiens periodic tryptophan protein
           2 protein.
          Length = 919

 Score =  702 bits (1734), Expect = 0.0
 Identities = 353/720 (49%), Positives = 478/720 (66%), Gaps = 22/720 (3%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           E+  F++ + +    DE TC+DW+  SR   VGSKD +T +   E  +N+  Y+L GH D
Sbjct: 130 EFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKD 189

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEF 129
            I+  FFE  SLDL ++S++G LC+W+     + L +K    +  K   LQ E   EEE 
Sbjct: 190 AIVACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPP--AGWKADLLQRE---EEE- 243

Query: 130 DAKDDIEKEKEYDSDRDAEQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLT 189
                 E+E++ + DR+       +    E+  K + Y +L +++     +  D    LT
Sbjct: 244 ------EEEEDQEGDRETTIRGKATPAEEEKTGK-VKYSRLAKYFFN---KEGDFN-NLT 292

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           A  +HK++ LLVTGF+SG+F LHE+P+ NLIH+LSIS+  I+S++++  GDWIAF C  +
Sbjct: 293 AAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGL 352

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           GQLLVWEWQSE YV+KQQGH   M  LAYSPDG ++VTGG DGKVKVWNT +GFCFVTF 
Sbjct: 353 GQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFT 412

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEF 369
           EH + V+GVT +A     V+SS+DGTVR +DL RYRNFRT TSP   QFSCVA+D+SGE 
Sbjct: 413 EHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEI 472

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            +AG QD FEIFVWS++ G+LL+VL GHE P+S L F+P    + LASASWD TVRLWD 
Sbjct: 473 VSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNP--MKSVLASASWDKTVRLWDM 530

Query: 430 IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            D     E + L SDAL V FRPDG E+AV+TL+  ITF++P    QTGS+EGR DL +G
Sbjct: 531 FDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTG 590

Query: 490 RAETDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKFVVTENRS 549
           R E D +T +   K KAFT +CYSADG  IL GG SK VC+Y V++ +L+K+F ++ N S
Sbjct: 591 RKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVREQILMKRFEISCNLS 650

Query: 550 LDAVNDFVNRRNLTEFGNMALLEEREDLEGGNVNIRLPGVKTGDMADRNVKPEVRVYCVR 609
           LDA+ +F+NRR +TEFGN+AL+++    E G V I LPGV+ GDM+ R+ KPE+RV  +R
Sbjct: 651 LDAMEEFLNRRKMTEFGNLALIDQDAGQEDG-VAIPLPGVRKGDMSSRHFKPEIRVTSLR 709

Query: 610 FSPTGESFAVAATEGLMLYSQNAGLDGTFRPYRLEATSTPAAVRQSLRDGAWGSALTGAL 669
           FSPTG  +A   TEGL++YS +  +   F P+ L+ + TP  VR++LR   +  A+  AL
Sbjct: 710 FSPTGRCWAATTTEGLLIYSLDTRV--LFDPFELDTSVTPGRVREALRQQDFTRAILMAL 767

Query: 670 QLAEQALIQECLESVPTKDISLTVSSLDEDYGDRLLSTIARLLEDSRHVEQLLHWTTALV 729
           +L E  L+QE LE+VP  +I +  SSL E Y +++L  +A   E SRH+E  L WT  L+
Sbjct: 768 RLNESKLVQEALEAVPRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLL 827


>U56085-1|AAC50904.1|  919|Homo sapiens periodic tryptophan protein
           2 protein.
          Length = 919

 Score =  702 bits (1734), Expect = 0.0
 Identities = 353/720 (49%), Positives = 478/720 (66%), Gaps = 22/720 (3%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           E+  F++ + +    DE TC+DW+  SR   VGSKD +T +   E  +N+  Y+L GH D
Sbjct: 130 EFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKD 189

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEF 129
            I+  FFE  SLDL ++S++G LC+W+     + L +K    +  K   LQ E   EEE 
Sbjct: 190 AIVACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPP--AGWKADLLQRE---EEE- 243

Query: 130 DAKDDIEKEKEYDSDRDAEQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLT 189
                 E+E++ + DR+       +    E+  K + Y +L +++     +  D    LT
Sbjct: 244 ------EEEEDQEGDRETTIRGKATPAEEEKTGK-VKYSRLAKYFFN---KEGDFN-NLT 292

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           A  +HK++ LLVTGF+SG+F LHE+P+ NLIH+LSIS+  I+S++++  GDWIAF C  +
Sbjct: 293 AAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGL 352

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           GQLLVWEWQSE YV+KQQGH   M  LAYSPDG ++VTGG DGKVKVWNT +GFCFVTF 
Sbjct: 353 GQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFT 412

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEF 369
           EH + V+GVT +A     V+SS+DGTVR +DL RYRNFRT TSP   QFSCVA+D+SGE 
Sbjct: 413 EHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEI 472

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            +AG QD FEIFVWS++ G+LL+VL GHE P+S L F+P    + LASASWD TVRLWD 
Sbjct: 473 VSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNP--MKSVLASASWDKTVRLWDM 530

Query: 430 IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            D     E + L SDAL V FRPDG E+AV+TL+  ITF++P    QTGS+EGR DL +G
Sbjct: 531 FDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTG 590

Query: 490 RAETDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKFVVTENRS 549
           R E D +T +   K KAFT +CYSADG  IL GG SK VC+Y V++ +L+K+F ++ N S
Sbjct: 591 RKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVREQILMKRFEISCNLS 650

Query: 550 LDAVNDFVNRRNLTEFGNMALLEEREDLEGGNVNIRLPGVKTGDMADRNVKPEVRVYCVR 609
           LDA+ +F+NRR +TEFGN+AL+++    E G V I LPGV+ GDM+ R+ KPE+RV  +R
Sbjct: 651 LDAMEEFLNRRKMTEFGNLALIDQDAGQEDG-VAIPLPGVRKGDMSSRHFKPEIRVTSLR 709

Query: 610 FSPTGESFAVAATEGLMLYSQNAGLDGTFRPYRLEATSTPAAVRQSLRDGAWGSALTGAL 669
           FSPTG  +A   TEGL++YS +  +   F P+ L+ + TP  VR++LR   +  A+  AL
Sbjct: 710 FSPTGRCWAATTTEGLLIYSLDTRV--LFDPFELDTSVTPGRVREALRQQDFTRAILMAL 767

Query: 670 QLAEQALIQECLESVPTKDISLTVSSLDEDYGDRLLSTIARLLEDSRHVEQLLHWTTALV 729
           +L E  L+QE LE+VP  +I +  SSL E Y +++L  +A   E SRH+E  L WT  L+
Sbjct: 768 RLNESKLVQEALEAVPRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLL 827


>U53346-1|AAB08084.1|  919|Homo sapiens PWP2H protein protein.
          Length = 919

 Score =  702 bits (1734), Expect = 0.0
 Identities = 353/720 (49%), Positives = 478/720 (66%), Gaps = 22/720 (3%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           E+  F++ + +    DE TC+DW+  SR   VGSKD +T +   E  +N+  Y+L GH D
Sbjct: 130 EFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKD 189

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEF 129
            I+  FFE  SLDL ++S++G LC+W+     + L +K    +  K   LQ E   EEE 
Sbjct: 190 AIVACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPP--AGWKADLLQRE---EEE- 243

Query: 130 DAKDDIEKEKEYDSDRDAEQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLT 189
                 E+E++ + DR+       +    E+  K + Y +L +++     +  D    LT
Sbjct: 244 ------EEEEDQEGDRETTIRGKATPAEEEKTGK-VKYSRLAKYFFN---KEGDFN-NLT 292

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           A  +HK++ LLVTGF+SG+F LHE+P+ NLIH+LSIS+  I+S++++  GDWIAF C  +
Sbjct: 293 AAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGL 352

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           GQLLVWEWQSE YV+KQQGH   M  LAYSPDG ++VTGG DGKVKVWNT +GFCFVTF 
Sbjct: 353 GQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFT 412

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEF 369
           EH + V+GVT +A     V+SS+DGTVR +DL RYRNFRT TSP   QFSCVA+D+SGE 
Sbjct: 413 EHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEI 472

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            +AG QD FEIFVWS++ G+LL+VL GHE P+S L F+P    + LASASWD TVRLWD 
Sbjct: 473 VSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNP--MKSVLASASWDKTVRLWDM 530

Query: 430 IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            D     E + L SDAL V FRPDG E+AV+TL+  ITF++P    QTGS+EGR DL +G
Sbjct: 531 FDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTG 590

Query: 490 RAETDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKFVVTENRS 549
           R E D +T +   K KAFT +CYSADG  IL GG SK VC+Y V++ +L+K+F ++ N S
Sbjct: 591 RKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVREQILMKRFEISCNLS 650

Query: 550 LDAVNDFVNRRNLTEFGNMALLEEREDLEGGNVNIRLPGVKTGDMADRNVKPEVRVYCVR 609
           LDA+ +F+NRR +TEFGN+AL+++    E G V I LPGV+ GDM+ R+ KPE+RV  +R
Sbjct: 651 LDAMEEFLNRRKMTEFGNLALIDQDAGQEDG-VAIPLPGVRKGDMSSRHFKPEIRVTSLR 709

Query: 610 FSPTGESFAVAATEGLMLYSQNAGLDGTFRPYRLEATSTPAAVRQSLRDGAWGSALTGAL 669
           FSPTG  +A   TEGL++YS +  +   F P+ L+ + TP  VR++LR   +  A+  AL
Sbjct: 710 FSPTGRCWAATTTEGLLIYSLDTRV--LFDPFELDTSVTPGRVREALRQQDFTRAILMAL 767

Query: 670 QLAEQALIQECLESVPTKDISLTVSSLDEDYGDRLLSTIARLLEDSRHVEQLLHWTTALV 729
           +L E  L+QE LE+VP  +I +  SSL E Y +++L  +A   E SRH+E  L WT  L+
Sbjct: 768 RLNESKLVQEALEAVPRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLL 827


>AP001753-1|BAA95553.1|  919|Homo sapiens periodic tryptophan
           protein 2 homolog protein.
          Length = 919

 Score =  702 bits (1734), Expect = 0.0
 Identities = 353/720 (49%), Positives = 478/720 (66%), Gaps = 22/720 (3%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           E+  F++ + +    DE TC+DW+  SR   VGSKD +T +   E  +N+  Y+L GH D
Sbjct: 130 EFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKD 189

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEF 129
            I+  FFE  SLDL ++S++G LC+W+     + L +K    +  K   LQ E   EEE 
Sbjct: 190 AIVACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPP--AGWKADLLQRE---EEE- 243

Query: 130 DAKDDIEKEKEYDSDRDAEQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLT 189
                 E+E++ + DR+       +    E+  K + Y +L +++     +  D    LT
Sbjct: 244 ------EEEEDQEGDRETTIRGKATPAEEEKTGK-VKYSRLAKYFFN---KEGDFN-NLT 292

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           A  +HK++ LLVTGF+SG+F LHE+P+ NLIH+LSIS+  I+S++++  GDWIAF C  +
Sbjct: 293 AAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGL 352

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           GQLLVWEWQSE YV+KQQGH   M  LAYSPDG ++VTGG DGKVKVWNT +GFCFVTF 
Sbjct: 353 GQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFT 412

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEF 369
           EH + V+GVT +A     V+SS+DGTVR +DL RYRNFRT TSP   QFSCVA+D+SGE 
Sbjct: 413 EHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEI 472

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            +AG QD FEIFVWS++ G+LL+VL GHE P+S L F+P    + LASASWD TVRLWD 
Sbjct: 473 VSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNP--MKSVLASASWDKTVRLWDM 530

Query: 430 IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            D     E + L SDAL V FRPDG E+AV+TL+  ITF++P    QTGS+EGR DL +G
Sbjct: 531 FDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTG 590

Query: 490 RAETDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKFVVTENRS 549
           R E D +T +   K KAFT +CYSADG  IL GG SK VC+Y V++ +L+K+F ++ N S
Sbjct: 591 RKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVREQILMKRFEISCNLS 650

Query: 550 LDAVNDFVNRRNLTEFGNMALLEEREDLEGGNVNIRLPGVKTGDMADRNVKPEVRVYCVR 609
           LDA+ +F+NRR +TEFGN+AL+++    E G V I LPGV+ GDM+ R+ KPE+RV  +R
Sbjct: 651 LDAMEEFLNRRKMTEFGNLALIDQDAGQEDG-VAIPLPGVRKGDMSSRHFKPEIRVTSLR 709

Query: 610 FSPTGESFAVAATEGLMLYSQNAGLDGTFRPYRLEATSTPAAVRQSLRDGAWGSALTGAL 669
           FSPTG  +A   TEGL++YS +  +   F P+ L+ + TP  VR++LR   +  A+  AL
Sbjct: 710 FSPTGRCWAATTTEGLLIYSLDTRV--LFDPFELDTSVTPGRVREALRQQDFTRAILMAL 767

Query: 670 QLAEQALIQECLESVPTKDISLTVSSLDEDYGDRLLSTIARLLEDSRHVEQLLHWTTALV 729
           +L E  L+QE LE+VP  +I +  SSL E Y +++L  +A   E SRH+E  L WT  L+
Sbjct: 768 RLNESKLVQEALEAVPRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLL 827


>AB001517-2|BAA21137.1|  919|Homo sapiens PWP2 protein protein.
          Length = 919

 Score =  702 bits (1734), Expect = 0.0
 Identities = 353/720 (49%), Positives = 478/720 (66%), Gaps = 22/720 (3%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           E+  F++ + +    DE TC+DW+  SR   VGSKD +T +   E  +N+  Y+L GH D
Sbjct: 130 EFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKD 189

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEF 129
            I+  FFE  SLDL ++S++G LC+W+     + L +K    +  K   LQ E   EEE 
Sbjct: 190 AIVACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPP--AGWKADLLQRE---EEE- 243

Query: 130 DAKDDIEKEKEYDSDRDAEQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLT 189
                 E+E++ + DR+       +    E+  K + Y +L +++     +  D    LT
Sbjct: 244 ------EEEEDQEGDRETTIRGKATPAEEEKTGK-VKYSRLAKYFFN---KEGDFN-NLT 292

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           A  +HK++ LLVTGF+SG+F LHE+P+ NLIH+LSIS+  I+S++++  GDWIAF C  +
Sbjct: 293 AAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGL 352

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           GQLLVWEWQSE YV+KQQGH   M  LAYSPDG ++VTGG DGKVKVWNT +GFCFVTF 
Sbjct: 353 GQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFT 412

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEF 369
           EH + V+GVT +A     V+SS+DGTVR +DL RYRNFRT TSP   QFSCVA+D+SGE 
Sbjct: 413 EHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEI 472

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            +AG QD FEIFVWS++ G+LL+VL GHE P+S L F+P    + LASASWD TVRLWD 
Sbjct: 473 VSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNP--MKSVLASASWDKTVRLWDM 530

Query: 430 IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            D     E + L SDAL V FRPDG E+AV+TL+  ITF++P    QTGS+EGR DL +G
Sbjct: 531 FDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTG 590

Query: 490 RAETDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKFVVTENRS 549
           R E D +T +   K KAFT +CYSADG  IL GG SK VC+Y V++ +L+K+F ++ N S
Sbjct: 591 RKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVREQILMKRFEISCNLS 650

Query: 550 LDAVNDFVNRRNLTEFGNMALLEEREDLEGGNVNIRLPGVKTGDMADRNVKPEVRVYCVR 609
           LDA+ +F+NRR +TEFGN+AL+++    E G V I LPGV+ GDM+ R+ KPE+RV  +R
Sbjct: 651 LDAMEEFLNRRKMTEFGNLALIDQDAGQEDG-VAIPLPGVRKGDMSSRHFKPEIRVTSLR 709

Query: 610 FSPTGESFAVAATEGLMLYSQNAGLDGTFRPYRLEATSTPAAVRQSLRDGAWGSALTGAL 669
           FSPTG  +A   TEGL++YS +  +   F P+ L+ + TP  VR++LR   +  A+  AL
Sbjct: 710 FSPTGRCWAATTTEGLLIYSLDTRV--LFDPFELDTSVTPGRVREALRQQDFTRAILMAL 767

Query: 670 QLAEQALIQECLESVPTKDISLTVSSLDEDYGDRLLSTIARLLEDSRHVEQLLHWTTALV 729
           +L E  L+QE LE+VP  +I +  SSL E Y +++L  +A   E SRH+E  L WT  L+
Sbjct: 768 RLNESKLVQEALEAVPRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLL 827


>X95263-1|CAA64560.1|  919|Homo sapiens PWP2 protein.
          Length = 919

 Score =  700 bits (1731), Expect = 0.0
 Identities = 353/720 (49%), Positives = 478/720 (66%), Gaps = 22/720 (3%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           E+  F++ + +    DE TC+DW+  SR   VGSKD +T +   E  +N+  Y+L GH D
Sbjct: 130 EFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKD 189

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEF 129
            I+  FFE  SLDL ++S++G LC+W+     + L +K    +  K   LQ E   EEE 
Sbjct: 190 AIVACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPP--AGWKADLLQRE---EEE- 243

Query: 130 DAKDDIEKEKEYDSDRDAEQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLT 189
                 E+E++ + DR+       +    E+  K + Y +L +++     +  D    LT
Sbjct: 244 ------EEEEDQEGDRETTIRGKATPAEEEKTGK-VKYSRLAKYFFN---KEGDFN-NLT 292

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           A  +HK++ LLVTGF+SG+F LHE+P+ NLIH+LSIS+  I+S++++  GDWIAF C  +
Sbjct: 293 AAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGL 352

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           GQLLVWEWQSE YV+KQQGH   M  LAYSPDG ++VTGG DGKVKVWNT +GFCFVTF 
Sbjct: 353 GQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFT 412

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEF 369
           EH + V+GVT +A     V+SS+DGTVR +DL RYRNFRT TSP   QFSCVA+D+SGE 
Sbjct: 413 EHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEI 472

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            +AG QD FEIFVWS++ G+LL+VL GHE P+S L F+P    + LASASWD TVRLWD 
Sbjct: 473 VSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNP--MKSVLASASWDKTVRLWDM 530

Query: 430 IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            D     E + L SDAL V FRPDG E+AV+TL+  ITF++P    QTGS+EGR DL +G
Sbjct: 531 FDSWRTKETLALTSDALAVTFRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTG 590

Query: 490 RAETDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKFVVTENRS 549
           R E D +T +   K KAFT +CYSADG  IL GG SK VC+Y V++ +L+K+F ++ N S
Sbjct: 591 RKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVREQILMKRFEISCNLS 650

Query: 550 LDAVNDFVNRRNLTEFGNMALLEEREDLEGGNVNIRLPGVKTGDMADRNVKPEVRVYCVR 609
           LDA+ +F+NRR +TEFGN+AL+++    E G V I LPGV+ GDM+ R+ KPE+RV  +R
Sbjct: 651 LDAMEEFLNRRKMTEFGNLALIDQDAGQEDG-VAIPLPGVRKGDMSSRHFKPEIRVTSLR 709

Query: 610 FSPTGESFAVAATEGLMLYSQNAGLDGTFRPYRLEATSTPAAVRQSLRDGAWGSALTGAL 669
           FSPTG  +A   TEGL++YS +  +   F P+ L+ + TP  VR++LR   +  A+  AL
Sbjct: 710 FSPTGRCWAGTTTEGLLIYSLDTRV--LFDPFELDTSVTPGRVREALRQQDFTRAILMAL 767

Query: 670 QLAEQALIQECLESVPTKDISLTVSSLDEDYGDRLLSTIARLLEDSRHVEQLLHWTTALV 729
           +L E  L+QE LE+VP  +I +  SSL E Y +++L  +A   E SRH+E  L WT  L+
Sbjct: 768 RLNESKLVQEALEAVPRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLL 827


>BC014988-1|AAH14988.1|  919|Homo sapiens PWP2 periodic tryptophan
           protein homolog (yeast) protein.
          Length = 919

 Score =  699 bits (1728), Expect = 0.0
 Identities = 352/720 (48%), Positives = 477/720 (66%), Gaps = 22/720 (3%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           E+  F++ + +    DE TC+DW+  SR   VGSKD +T +   E  +N+  Y+L GH D
Sbjct: 130 EFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKD 189

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEF 129
            I+  FFE  SLDL ++S++G LC+W+     + L +K    +  K   LQ E   EEE 
Sbjct: 190 AIVACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPP--AGWKADLLQRE---EEE- 243

Query: 130 DAKDDIEKEKEYDSDRDAEQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLT 189
                 E+E++ + DR+       +    E+  K + Y +L +++     +  D    LT
Sbjct: 244 ------EEEEDQEGDRETTIRGKATPAEEEKTGK-VKYSRLAKYFFN---KEGDFN-NLT 292

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           A  +HK++ LLVTGF+SG+F LHE+P+ NLIH+LSIS+  I+S++++  GDWIAF C  +
Sbjct: 293 AAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGL 352

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           GQLLVWEWQSE YV+KQQGH   M  LAYSPDG ++VTGG DGKVKVWNT +GFCFVTF 
Sbjct: 353 GQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFT 412

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEF 369
           EH + V+GVT +A     V+SS+DGTVR +DL RYRNFRT TSP   QFSCVA+D+SGE 
Sbjct: 413 EHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEI 472

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            +AG QD FEIFVWS++ G+LL+VL GHE P+S L F+P    + LASASWD TVRLWD 
Sbjct: 473 VSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNP--MKSVLASASWDKTVRLWDM 530

Query: 430 IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            D     E + L SDAL V  RPDG E+AV+TL+  ITF++P    QTGS+EGR DL +G
Sbjct: 531 FDSWRTKETLALTSDALAVTIRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTG 590

Query: 490 RAETDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKFVVTENRS 549
           R E D +T +   K KAFT +CYSADG  IL GG SK VC+Y V++ +L+K+F ++ N S
Sbjct: 591 RKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVREQILMKRFEISCNLS 650

Query: 550 LDAVNDFVNRRNLTEFGNMALLEEREDLEGGNVNIRLPGVKTGDMADRNVKPEVRVYCVR 609
           LDA+ +F+NRR +TEFGN+AL+++    E G V I LPGV+ GDM+ R+ KPE+RV  +R
Sbjct: 651 LDAMEEFLNRRKMTEFGNLALIDQDAGQEDG-VAIPLPGVRKGDMSSRHFKPEIRVTSLR 709

Query: 610 FSPTGESFAVAATEGLMLYSQNAGLDGTFRPYRLEATSTPAAVRQSLRDGAWGSALTGAL 669
           FSPTG  +A   TEGL++YS +  +   F P+ L+ + TP  VR++LR   +  A+  AL
Sbjct: 710 FSPTGRCWAATTTEGLLIYSLDTRV--LFDPFELDTSVTPGRVREALRQQDFTRAILMAL 767

Query: 670 QLAEQALIQECLESVPTKDISLTVSSLDEDYGDRLLSTIARLLEDSRHVEQLLHWTTALV 729
           +L E  L+QE LE+VP  +I +  SSL E Y +++L  +A   E SRH+E  L WT  L+
Sbjct: 768 RLNESKLVQEALEAVPRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLL 827


>BC013309-1|AAH13309.1|  919|Homo sapiens PWP2 periodic tryptophan
           protein homolog (yeast) protein.
          Length = 919

 Score =  699 bits (1728), Expect = 0.0
 Identities = 352/720 (48%), Positives = 477/720 (66%), Gaps = 22/720 (3%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           E+  F++ + +    DE TC+DW+  SR   VGSKD +T +   E  +N+  Y+L GH D
Sbjct: 130 EFNAFVLDKTYFGPYDETTCIDWTDDSRCFVVGSKDMSTWVFGAERWDNLIYYALGGHKD 189

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEF 129
            I+  FFE  SLDL ++S++G LC+W+     + L +K    +  K   LQ E   EEE 
Sbjct: 190 AIVACFFESNSLDLYSLSQDGVLCMWQCDTPPEGLRLKPP--AGWKADLLQRE---EEE- 243

Query: 130 DAKDDIEKEKEYDSDRDAEQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLT 189
                 E+E++ + DR+       +    E+  K + Y +L +++     +  D    LT
Sbjct: 244 ------EEEEDQEGDRETTIRGKATPAEEEKTGK-VKYSRLAKYFFN---KEGDFN-NLT 292

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           A  +HK++ LLVTGF+SG+F LHE+P+ NLIH+LSIS+  I+S++++  GDWIAF C  +
Sbjct: 293 AAAFHKKSHLLVTGFASGIFHLHELPEFNLIHSLSISDQSIASVAINSSGDWIAFGCSGL 352

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           GQLLVWEWQSE YV+KQQGH   M  LAYSPDG ++VTGG DGKVKVWNT +GFCFVTF 
Sbjct: 353 GQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCFVTFT 412

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEF 369
           EH + V+GVT +A     V+SS+DGTVR +DL RYRNFRT TSP   QFSCVA+D+SGE 
Sbjct: 413 EHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDASGEI 472

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            +AG QD FEIFVWS++ G+LL+VL GHE P+S L F+P    + LASASWD TVRLWD 
Sbjct: 473 VSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNP--MKSVLASASWDKTVRLWDM 530

Query: 430 IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            D     E + L SDAL V  RPDG E+AV+TL+  ITF++P    QTGS+EGR DL +G
Sbjct: 531 FDSWRTKETLALTSDALAVTIRPDGAELAVATLNSQITFWDPENAVQTGSIEGRHDLKTG 590

Query: 490 RAETDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKFVVTENRS 549
           R E D +T +   K KAFT +CYSADG  IL GG SK VC+Y V++ +L+K+F ++ N S
Sbjct: 591 RKELDKITAKHAAKGKAFTALCYSADGHSILAGGMSKFVCIYHVREQILMKRFEISCNLS 650

Query: 550 LDAVNDFVNRRNLTEFGNMALLEEREDLEGGNVNIRLPGVKTGDMADRNVKPEVRVYCVR 609
           LDA+ +F+NRR +TEFGN+AL+++    E G V I LPGV+ GDM+ R+ KPE+RV  +R
Sbjct: 651 LDAMEEFLNRRKMTEFGNLALIDQDAGQEDG-VAIPLPGVRKGDMSSRHFKPEIRVTSLR 709

Query: 610 FSPTGESFAVAATEGLMLYSQNAGLDGTFRPYRLEATSTPAAVRQSLRDGAWGSALTGAL 669
           FSPTG  +A   TEGL++YS +  +   F P+ L+ + TP  VR++LR   +  A+  AL
Sbjct: 710 FSPTGRCWAATTTEGLLIYSLDTRV--LFDPFELDTSVTPGRVREALRQQDFTRAILMAL 767

Query: 670 QLAEQALIQECLESVPTKDISLTVSSLDEDYGDRLLSTIARLLEDSRHVEQLLHWTTALV 729
           +L E  L+QE LE+VP  +I +  SSL E Y +++L  +A   E SRH+E  L WT  L+
Sbjct: 768 RLNESKLVQEALEAVPRGEIEVVTSSLPELYVEKVLEFLASSFEVSRHLEFYLLWTHKLL 827


>AB209438-1|BAD92675.1|  316|Homo sapiens PWP2 periodic tryptophan
           protein homolog protein.
          Length = 316

 Score =  268 bits (657), Expect = 5e-71
 Identities = 126/199 (63%), Positives = 148/199 (74%), Gaps = 2/199 (1%)

Query: 246 CPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCF 305
           C  +GQLLVWEWQSE YV+KQQGH   M  LAYSPDG ++VTGG DGKVKVWNT +GFCF
Sbjct: 69  CTGLGQLLVWEWQSESYVLKQQGHFNSMVALAYSPDGQYIVTGGDDGKVKVWNTLSGFCF 128

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
           VTF EH + V+GVT +A     V+SS+DGTVR +DL RYRNFRT TSP   QFSCVA+D+
Sbjct: 129 VTFTEHSSGVTGVTFTATGYVVVTSSMDGTVRAFDLHRYRNFRTFTSPRPTQFSCVAVDA 188

Query: 366 SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVR 425
           SGE  +AG QD FEIFVWS++ G+LL+VL GHE P+S L F+P    + LASASWD TVR
Sbjct: 189 SGEIVSAGAQDSFEIFVWSMQTGRLLDVLSGHEGPISGLCFNP--MKSVLASASWDKTVR 246

Query: 426 LWDCIDREVQCEPIRLNSD 444
           LWD  D     E + L SD
Sbjct: 247 LWDMFDSWRTKETLALTSD 265


>BC013997-1|AAH13997.1|  353|Homo sapiens guanine nucleotide binding
           protein (G protein), beta 5 protein.
          Length = 353

 Score =  102 bits (244), Expect = 5e-21
 Identities = 62/181 (34%), Positives = 86/181 (47%), Gaps = 6/181 (3%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPD--GLHVVTGGFDGKVKVWNTTNGFCFVT 307
           G   +W+ +S Q +    GH  D+ CL  +P   G   V+GG D K  VW+  +G C   
Sbjct: 175 GTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQA 234

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSS 366
           F  H++ ++ V    +   F S S D T R YDL   R     +  S++   S V    S
Sbjct: 235 FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLS 294

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
           G    AG  D + I VW +  G  + +L GHE  VS+L  SP    T   S SWD T+R+
Sbjct: 295 GRLLFAGYND-YTINVWDVLKGSRVSILFGHENRVSTLRVSP--DGTAFCSGSWDHTLRV 351

Query: 427 W 427
           W
Sbjct: 352 W 352



 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 57/227 (25%), Positives = 85/227 (37%), Gaps = 26/227 (11%)

Query: 261 QYVMKQQ----GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKAT-- 314
           Q+VMK +    GH   + C+ +  D   +V+   DGKV VW++     F T  EH  T  
Sbjct: 50  QFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDS-----FTTNKEHAVTMP 104

Query: 315 ---VSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQF------SCVALDS 365
              V     + +        LD     Y LT  +N         V        +C   +S
Sbjct: 105 CTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNS 164

Query: 366 SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVR 425
             +   A G     +  W ++ G+LL+   GH A V  L  +P+ T     S   D    
Sbjct: 165 DMQILTASGDGTCAL--WDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAM 222

Query: 426 LWDCIDREVQCEPI--RLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           +WD   R  QC        SD   V + P G+  A  + D     ++
Sbjct: 223 VWDM--RSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYD 267


>AF501885-1|AAM15921.1|  353|Homo sapiens guanine nucleotide binding
           protein beta 5 protein.
          Length = 353

 Score =  102 bits (244), Expect = 5e-21
 Identities = 62/181 (34%), Positives = 86/181 (47%), Gaps = 6/181 (3%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPD--GLHVVTGGFDGKVKVWNTTNGFCFVT 307
           G   +W+ +S Q +    GH  D+ CL  +P   G   V+GG D K  VW+  +G C   
Sbjct: 175 GTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQA 234

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSS 366
           F  H++ ++ V    +   F S S D T R YDL   R     +  S++   S V    S
Sbjct: 235 FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLS 294

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
           G    AG  D + I VW +  G  + +L GHE  VS+L  SP    T   S SWD T+R+
Sbjct: 295 GRLLFAGYND-YTINVWDVLKGSRVSILFGHENRVSTLRVSP--DGTAFCSGSWDHTLRV 351

Query: 427 W 427
           W
Sbjct: 352 W 352



 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 57/227 (25%), Positives = 85/227 (37%), Gaps = 26/227 (11%)

Query: 261 QYVMKQQ----GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKAT-- 314
           Q+VMK +    GH   + C+ +  D   +V+   DGKV VW++     F T  EH  T  
Sbjct: 50  QFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDS-----FTTNKEHAVTMP 104

Query: 315 ---VSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQF------SCVALDS 365
              V     + +        LD     Y LT  +N         V        +C   +S
Sbjct: 105 CTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNS 164

Query: 366 SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVR 425
             +   A G     +  W ++ G+LL+   GH A V  L  +P+ T     S   D    
Sbjct: 165 DMQILTASGDGTCAL--WDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAM 222

Query: 426 LWDCIDREVQCEPI--RLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           +WD   R  QC        SD   V + P G+  A  + D     ++
Sbjct: 223 VWDM--RSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYD 267


>AF300650-1|AAG18444.1|  395|Homo sapiens guanine nucleotide binding
           protein beta subunit 5L protein.
          Length = 395

 Score =  102 bits (244), Expect = 5e-21
 Identities = 62/181 (34%), Positives = 86/181 (47%), Gaps = 6/181 (3%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPD--GLHVVTGGFDGKVKVWNTTNGFCFVT 307
           G   +W+ +S Q +    GH  D+ CL  +P   G   V+GG D K  VW+  +G C   
Sbjct: 217 GTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQA 276

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSS 366
           F  H++ ++ V    +   F S S D T R YDL   R     +  S++   S V    S
Sbjct: 277 FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLS 336

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
           G    AG  D + I VW +  G  + +L GHE  VS+L  SP    T   S SWD T+R+
Sbjct: 337 GRLLFAGYND-YTINVWDVLKGSRVSILFGHENRVSTLRVSP--DGTAFCSGSWDHTLRV 393

Query: 427 W 427
           W
Sbjct: 394 W 394



 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 57/227 (25%), Positives = 85/227 (37%), Gaps = 26/227 (11%)

Query: 261 QYVMKQQ----GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKAT-- 314
           Q+VMK +    GH   + C+ +  D   +V+   DGKV VW++     F T  EH  T  
Sbjct: 92  QFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDS-----FTTNKEHAVTMP 146

Query: 315 ---VSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQF------SCVALDS 365
              V     + +        LD     Y LT  +N         V        +C   +S
Sbjct: 147 CTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNS 206

Query: 366 SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVR 425
             +   A G     +  W ++ G+LL+   GH A V  L  +P+ T     S   D    
Sbjct: 207 DMQILTASGDGTCAL--WDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAM 264

Query: 426 LWDCIDREVQCEPI--RLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           +WD   R  QC        SD   V + P G+  A  + D     ++
Sbjct: 265 VWDM--RSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYD 309


>AF017656-1|AAC63826.1|  353|Homo sapiens G protein beta 5 subunit
           protein.
          Length = 353

 Score =  102 bits (244), Expect = 5e-21
 Identities = 62/181 (34%), Positives = 86/181 (47%), Gaps = 6/181 (3%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPD--GLHVVTGGFDGKVKVWNTTNGFCFVT 307
           G   +W+ +S Q +    GH  D+ CL  +P   G   V+GG D K  VW+  +G C   
Sbjct: 175 GTCALWDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAMVWDMRSGQCVQA 234

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSS 366
           F  H++ ++ V    +   F S S D T R YDL   R     +  S++   S V    S
Sbjct: 235 FETHESDINSVRYYPSGDAFASGSDDATCRLYDLRADREVAIYSKESIIFGASSVDFSLS 294

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
           G    AG  D + I VW +  G  + +L GHE  VS+L  SP    T   S SWD T+R+
Sbjct: 295 GRLLFAGYND-YTINVWDVLKGSRVSILFGHENRVSTLRVSP--DGTAFCSGSWDHTLRV 351

Query: 427 W 427
           W
Sbjct: 352 W 352



 Score = 58.0 bits (134), Expect = 1e-07
 Identities = 57/227 (25%), Positives = 85/227 (37%), Gaps = 26/227 (11%)

Query: 261 QYVMKQQ----GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKAT-- 314
           Q+VMK +    GH   + C+ +  D   +V+   DGKV VW++     F T  EH  T  
Sbjct: 50  QFVMKTRRTLKGHGNKVLCMDWCKDKRRIVSSSQDGKVIVWDS-----FTTNKEHAVTMP 104

Query: 315 ---VSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQF------SCVALDS 365
              V     + +        LD     Y LT  +N         V        +C   +S
Sbjct: 105 CTWVMACAYAPSGCAIACGGLDNKCSVYPLTFDKNENMAAKKKSVAMHTNYLSACSFTNS 164

Query: 366 SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVR 425
             +   A G     +  W ++ G+LL+   GH A V  L  +P+ T     S   D    
Sbjct: 165 DMQILTASGDGTCAL--WDVESGQLLQSFHGHGADVLCLDLAPSETGNTFVSGGCDKKAM 222

Query: 426 LWDCIDREVQCEPI--RLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           +WD   R  QC        SD   V + P G+  A  + D     ++
Sbjct: 223 VWDM--RSGQCVQAFETHESDINSVRYYPSGDAFASGSDDATCRLYD 267


>BX649632-1|CAI18774.1|  334|Homo sapiens WD repeat domain 5
           protein.
          Length = 334

 Score = 93.1 bits (221), Expect = 3e-18
 Identities = 58/208 (27%), Positives = 103/208 (49%), Gaps = 9/208 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH+  ++ + +SP+G  + +   D  +K+W   +G    T   HK  +S V  S++    
Sbjct: 43  GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 102

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS+S D T++ +D++  +  +TL   S   F C   +       +G  D   + +W +K 
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVF-CCNFNPQSNLIVSGSFDE-SVRIWDVKT 160

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQ 447
           GK L+ L  H  PVS++ F+     + + S+S+DG  R+WD      QC    ++ D   
Sbjct: 161 GKCLKTLPAHSDPVSAVHFN--RDGSLIVSSSYDGLCRIWDTASG--QCLKTLIDDDNPP 216

Query: 448 VA---FRPDGEEIAVSTLDGNITFFEPS 472
           V+   F P+G+ I  +TLD  +  ++ S
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYS 244



 Score = 85.8 bits (203), Expect = 5e-16
 Identities = 55/250 (22%), Positives = 123/250 (49%), Gaps = 7/250 (2%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+ ++ V +  ++ LLV+        + ++     + TL    + +   + +P  + I  
Sbjct: 87  KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVS 146

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
              +   + +W+ ++ + +     HS  ++ + ++ DG  +V+  +DG  ++W+T +G C
Sbjct: 147 GSFD-ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQC 205

Query: 305 FVTF-HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             T   +    VS V  S N K+ ++++LD T++ +D ++ +  +T T     ++   A 
Sbjct: 206 LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFAN 265

Query: 364 DS--SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
            S   G++  +G +D   +++W+++  ++++ L GH   V S A  PT      A+   D
Sbjct: 266 FSVTGGKWIVSGSEDNL-VYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEND 324

Query: 422 GTVRLW--DC 429
            T++LW  DC
Sbjct: 325 KTIKLWKSDC 334



 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 66/282 (23%), Positives = 126/282 (44%), Gaps = 5/282 (1%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V++    + L +  +  L  +    D     T+S  +  IS ++ S   + +  A  
Sbjct: 48  VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 107

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           +   L +W+  S + +   +GHS  + C  ++P    +V+G FD  V++W+   G C  T
Sbjct: 108 D-KTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKT 166

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSG 367
              H   VS V  + +    VSSS DG  R +D    +  +TL        S V    +G
Sbjct: 167 LPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG 226

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR-LASASWDGTVRL 426
           ++  A   D   + +W    GK L+   GH+     +  + ++T  + + S S D  V +
Sbjct: 227 KYILAATLD-NTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 285

Query: 427 WDCIDREVQCEPIRLNSD-ALQVAFRPDGEEIAVSTLDGNIT 467
           W+   +E+  + ++ ++D  +  A  P    IA + L+ + T
Sbjct: 286 WNLQTKEI-VQKLQGHTDVVISTACHPTENIIASAALENDKT 326



 Score = 82.6 bits (195), Expect = 5e-15
 Identities = 57/215 (26%), Positives = 98/215 (45%), Gaps = 6/215 (2%)

Query: 215 PDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMT 274
           P+  L  TL+     +SS+  SP G+W+A +  +   + +W     ++     GH L ++
Sbjct: 33  PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSAD-KLIKIWGAYDGKFEKTISGHKLGIS 91

Query: 275 CLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDG 334
            +A+S D   +V+   D  +K+W+ ++G C  T   H   V     +      VS S D 
Sbjct: 92  DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDE 151

Query: 335 TVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVL 394
           +VR +D+   +  +TL + S    S V  +  G    +   D     +W    G+ L+ L
Sbjct: 152 SVRIWDVKTGKCLKTLPAHS-DPVSAVHFNRDGSLIVSSSYDGL-CRIWDTASGQCLKTL 209

Query: 395 -GGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
                 PVS + FSP      + +A+ D T++LWD
Sbjct: 210 IDDDNPPVSFVKFSP--NGKYILAATLDNTLKLWD 242



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 18/72 (25%), Positives = 36/72 (50%), Gaps = 2/72 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C +++  S L+  GS D + +I  V+      + +L  H+D +  V F R    +++ 
Sbjct: 132 VFCCNFNPQSNLIVSGSFDESVRIWDVK--TGKCLKTLPAHSDPVSAVHFNRDGSLIVSS 189

Query: 87  SRNGQLCLWEAS 98
           S +G   +W+ +
Sbjct: 190 SYDGLCRIWDTA 201


>BC001635-1|AAH01635.1|  334|Homo sapiens WD repeat domain 5
           protein.
          Length = 334

 Score = 93.1 bits (221), Expect = 3e-18
 Identities = 58/208 (27%), Positives = 103/208 (49%), Gaps = 9/208 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH+  ++ + +SP+G  + +   D  +K+W   +G    T   HK  +S V  S++    
Sbjct: 43  GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 102

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS+S D T++ +D++  +  +TL   S   F C   +       +G  D   + +W +K 
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVF-CCNFNPQSNLIVSGSFDE-SVRIWDVKT 160

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQ 447
           GK L+ L  H  PVS++ F+     + + S+S+DG  R+WD      QC    ++ D   
Sbjct: 161 GKCLKTLPAHSDPVSAVHFN--RDGSLIVSSSYDGLCRIWDTASG--QCLKTLIDDDNPP 216

Query: 448 VA---FRPDGEEIAVSTLDGNITFFEPS 472
           V+   F P+G+ I  +TLD  +  ++ S
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYS 244



 Score = 85.8 bits (203), Expect = 5e-16
 Identities = 55/250 (22%), Positives = 123/250 (49%), Gaps = 7/250 (2%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+ ++ V +  ++ LLV+        + ++     + TL    + +   + +P  + I  
Sbjct: 87  KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVS 146

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
              +   + +W+ ++ + +     HS  ++ + ++ DG  +V+  +DG  ++W+T +G C
Sbjct: 147 GSFD-ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQC 205

Query: 305 FVTF-HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             T   +    VS V  S N K+ ++++LD T++ +D ++ +  +T T     ++   A 
Sbjct: 206 LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFAN 265

Query: 364 DS--SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
            S   G++  +G +D   +++W+++  ++++ L GH   V S A  PT      A+   D
Sbjct: 266 FSVTGGKWIVSGSEDNL-VYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEND 324

Query: 422 GTVRLW--DC 429
            T++LW  DC
Sbjct: 325 KTIKLWKSDC 334



 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 66/282 (23%), Positives = 126/282 (44%), Gaps = 5/282 (1%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V++    + L +  +  L  +    D     T+S  +  IS ++ S   + +  A  
Sbjct: 48  VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 107

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           +   L +W+  S + +   +GHS  + C  ++P    +V+G FD  V++W+   G C  T
Sbjct: 108 D-KTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKT 166

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSG 367
              H   VS V  + +    VSSS DG  R +D    +  +TL        S V    +G
Sbjct: 167 LPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG 226

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR-LASASWDGTVRL 426
           ++  A   D   + +W    GK L+   GH+     +  + ++T  + + S S D  V +
Sbjct: 227 KYILAATLD-NTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 285

Query: 427 WDCIDREVQCEPIRLNSD-ALQVAFRPDGEEIAVSTLDGNIT 467
           W+   +E+  + ++ ++D  +  A  P    IA + L+ + T
Sbjct: 286 WNLQTKEI-VQKLQGHTDVVISTACHPTENIIASAALENDKT 326



 Score = 82.6 bits (195), Expect = 5e-15
 Identities = 57/215 (26%), Positives = 98/215 (45%), Gaps = 6/215 (2%)

Query: 215 PDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMT 274
           P+  L  TL+     +SS+  SP G+W+A +  +   + +W     ++     GH L ++
Sbjct: 33  PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSAD-KLIKIWGAYDGKFEKTISGHKLGIS 91

Query: 275 CLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDG 334
            +A+S D   +V+   D  +K+W+ ++G C  T   H   V     +      VS S D 
Sbjct: 92  DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDE 151

Query: 335 TVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVL 394
           +VR +D+   +  +TL + S    S V  +  G    +   D     +W    G+ L+ L
Sbjct: 152 SVRIWDVKTGKCLKTLPAHS-DPVSAVHFNRDGSLIVSSSYDGL-CRIWDTASGQCLKTL 209

Query: 395 -GGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
                 PVS + FSP      + +A+ D T++LWD
Sbjct: 210 IDDDNPPVSFVKFSP--NGKYILAATLDNTLKLWD 242



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 18/72 (25%), Positives = 36/72 (50%), Gaps = 2/72 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C +++  S L+  GS D + +I  V+      + +L  H+D +  V F R    +++ 
Sbjct: 132 VFCCNFNPQSNLIVSGSFDESVRIWDVK--TGKCLKTLPAHSDPVSAVHFNRDGSLIVSS 189

Query: 87  SRNGQLCLWEAS 98
           S +G   +W+ +
Sbjct: 190 SYDGLCRIWDTA 201


>AK000552-1|BAA91248.1|  334|Homo sapiens protein ( Homo sapiens
           cDNA FLJ20545 fis, clone KAT11476. ).
          Length = 334

 Score = 93.1 bits (221), Expect = 3e-18
 Identities = 58/208 (27%), Positives = 103/208 (49%), Gaps = 9/208 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH+  ++ + +SP+G  + +   D  +K+W   +G    T   HK  +S V  S++    
Sbjct: 43  GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 102

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS+S D T++ +D++  +  +TL   S   F C   +       +G  D   + +W +K 
Sbjct: 103 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVF-CCNFNPQSNLIVSGSFDE-SVRIWDVKT 160

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQ 447
           GK L+ L  H  PVS++ F+     + + S+S+DG  R+WD      QC    ++ D   
Sbjct: 161 GKCLKTLPAHSDPVSAVHFN--RDGSLIVSSSYDGLCRIWDTASG--QCLKTLIDDDNPP 216

Query: 448 VA---FRPDGEEIAVSTLDGNITFFEPS 472
           V+   F P+G+ I  +TLD  +  ++ S
Sbjct: 217 VSFVKFSPNGKYILAATLDNTLKLWDYS 244



 Score = 85.8 bits (203), Expect = 5e-16
 Identities = 55/250 (22%), Positives = 123/250 (49%), Gaps = 7/250 (2%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+ ++ V +  ++ LLV+        + ++     + TL    + +   + +P  + I  
Sbjct: 87  KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVS 146

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
              +   + +W+ ++ + +     HS  ++ + ++ DG  +V+  +DG  ++W+T +G C
Sbjct: 147 GSFD-ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQC 205

Query: 305 FVTF-HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             T   +    VS V  S N K+ ++++LD T++ +D ++ +  +T T     ++   A 
Sbjct: 206 LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFAN 265

Query: 364 DS--SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
            S   G++  +G +D   +++W+++  ++++ L GH   V S A  PT      A+   D
Sbjct: 266 FSVTGGKWIVSGSEDNL-VYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEND 324

Query: 422 GTVRLW--DC 429
            T++LW  DC
Sbjct: 325 KTIKLWKSDC 334



 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 66/282 (23%), Positives = 126/282 (44%), Gaps = 5/282 (1%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V++    + L +  +  L  +    D     T+S  +  IS ++ S   + +  A  
Sbjct: 48  VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 107

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           +   L +W+  S + +   +GHS  + C  ++P    +V+G FD  V++W+   G C  T
Sbjct: 108 D-KTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKT 166

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSG 367
              H   VS V  + +    VSSS DG  R +D    +  +TL        S V    +G
Sbjct: 167 LPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG 226

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR-LASASWDGTVRL 426
           ++  A   D   + +W    GK L+   GH+     +  + ++T  + + S S D  V +
Sbjct: 227 KYILAATLD-NTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 285

Query: 427 WDCIDREVQCEPIRLNSD-ALQVAFRPDGEEIAVSTLDGNIT 467
           W+   +E+  + ++ ++D  +  A  P    IA + L+ + T
Sbjct: 286 WNLQTKEI-VQKLQGHTDVVISTACHPTENIIASAALENDKT 326



 Score = 82.6 bits (195), Expect = 5e-15
 Identities = 57/215 (26%), Positives = 98/215 (45%), Gaps = 6/215 (2%)

Query: 215 PDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMT 274
           P+  L  TL+     +SS+  SP G+W+A +  +   + +W     ++     GH L ++
Sbjct: 33  PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSAD-KLIKIWGAYDGKFEKTISGHKLGIS 91

Query: 275 CLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDG 334
            +A+S D   +V+   D  +K+W+ ++G C  T   H   V     +      VS S D 
Sbjct: 92  DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDE 151

Query: 335 TVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVL 394
           +VR +D+   +  +TL + S    S V  +  G    +   D     +W    G+ L+ L
Sbjct: 152 SVRIWDVKTGKCLKTLPAHS-DPVSAVHFNRDGSLIVSSSYDGL-CRIWDTASGQCLKTL 209

Query: 395 -GGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
                 PVS + FSP      + +A+ D T++LWD
Sbjct: 210 IDDDNPPVSFVKFSP--NGKYILAATLDNTLKLWD 242



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 18/72 (25%), Positives = 36/72 (50%), Gaps = 2/72 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C +++  S L+  GS D + +I  V+      + +L  H+D +  V F R    +++ 
Sbjct: 132 VFCCNFNPQSNLIVSGSFDESVRIWDVK--TGKCLKTLPAHSDPVSAVHFNRDGSLIVSS 189

Query: 87  SRNGQLCLWEAS 98
           S +G   +W+ +
Sbjct: 190 SYDGLCRIWDTA 201


>AJ011376-1|CAB66159.1|  362|Homo sapiens hypothetical protein
           protein.
          Length = 362

 Score = 93.1 bits (221), Expect = 3e-18
 Identities = 58/208 (27%), Positives = 103/208 (49%), Gaps = 9/208 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH+  ++ + +SP+G  + +   D  +K+W   +G    T   HK  +S V  S++    
Sbjct: 71  GHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLL 130

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS+S D T++ +D++  +  +TL   S   F C   +       +G  D   + +W +K 
Sbjct: 131 VSASDDKTLKIWDVSSGKCLKTLKGHSNYVF-CCNFNPQSNLIVSGSFDE-SVRIWDVKT 188

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQ 447
           GK L+ L  H  PVS++ F+     + + S+S+DG  R+WD      QC    ++ D   
Sbjct: 189 GKCLKTLPAHSDPVSAVHFN--RDGSLIVSSSYDGLCRIWDTASG--QCLKTLIDDDNPP 244

Query: 448 VA---FRPDGEEIAVSTLDGNITFFEPS 472
           V+   F P+G+ I  +TLD  +  ++ S
Sbjct: 245 VSFVKFSPNGKYILAATLDNTLKLWDYS 272



 Score = 85.8 bits (203), Expect = 5e-16
 Identities = 55/250 (22%), Positives = 123/250 (49%), Gaps = 7/250 (2%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+ ++ V +  ++ LLV+        + ++     + TL    + +   + +P  + I  
Sbjct: 115 KLGISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVS 174

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
              +   + +W+ ++ + +     HS  ++ + ++ DG  +V+  +DG  ++W+T +G C
Sbjct: 175 GSFD-ESVRIWDVKTGKCLKTLPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQC 233

Query: 305 FVTF-HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             T   +    VS V  S N K+ ++++LD T++ +D ++ +  +T T     ++   A 
Sbjct: 234 LKTLIDDDNPPVSFVKFSPNGKYILAATLDNTLKLWDYSKGKCLKTYTGHKNEKYCIFAN 293

Query: 364 DS--SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
            S   G++  +G +D   +++W+++  ++++ L GH   V S A  PT      A+   D
Sbjct: 294 FSVTGGKWIVSGSEDNL-VYIWNLQTKEIVQKLQGHTDVVISTACHPTENIIASAALEND 352

Query: 422 GTVRLW--DC 429
            T++LW  DC
Sbjct: 353 KTIKLWKSDC 362



 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 66/282 (23%), Positives = 126/282 (44%), Gaps = 5/282 (1%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V++    + L +  +  L  +    D     T+S  +  IS ++ S   + +  A  
Sbjct: 76  VSSVKFSPNGEWLASSSADKLIKIWGAYDGKFEKTISGHKLGISDVAWSSDSNLLVSASD 135

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           +   L +W+  S + +   +GHS  + C  ++P    +V+G FD  V++W+   G C  T
Sbjct: 136 D-KTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKT 194

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSG 367
              H   VS V  + +    VSSS DG  R +D    +  +TL        S V    +G
Sbjct: 195 LPAHSDPVSAVHFNRDGSLIVSSSYDGLCRIWDTASGQCLKTLIDDDNPPVSFVKFSPNG 254

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR-LASASWDGTVRL 426
           ++  A   D   + +W    GK L+   GH+     +  + ++T  + + S S D  V +
Sbjct: 255 KYILAATLD-NTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 313

Query: 427 WDCIDREVQCEPIRLNSD-ALQVAFRPDGEEIAVSTLDGNIT 467
           W+   +E+  + ++ ++D  +  A  P    IA + L+ + T
Sbjct: 314 WNLQTKEI-VQKLQGHTDVVISTACHPTENIIASAALENDKT 354



 Score = 82.6 bits (195), Expect = 5e-15
 Identities = 57/215 (26%), Positives = 98/215 (45%), Gaps = 6/215 (2%)

Query: 215 PDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMT 274
           P+  L  TL+     +SS+  SP G+W+A +  +   + +W     ++     GH L ++
Sbjct: 61  PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSAD-KLIKIWGAYDGKFEKTISGHKLGIS 119

Query: 275 CLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDG 334
            +A+S D   +V+   D  +K+W+ ++G C  T   H   V     +      VS S D 
Sbjct: 120 DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTLKGHSNYVFCCNFNPQSNLIVSGSFDE 179

Query: 335 TVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVL 394
           +VR +D+   +  +TL + S    S V  +  G    +   D     +W    G+ L+ L
Sbjct: 180 SVRIWDVKTGKCLKTLPAHS-DPVSAVHFNRDGSLIVSSSYDGL-CRIWDTASGQCLKTL 237

Query: 395 -GGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
                 PVS + FSP      + +A+ D T++LWD
Sbjct: 238 IDDDNPPVSFVKFSP--NGKYILAATLDNTLKLWD 270



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 18/72 (25%), Positives = 36/72 (50%), Gaps = 2/72 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C +++  S L+  GS D + +I  V+      + +L  H+D +  V F R    +++ 
Sbjct: 160 VFCCNFNPQSNLIVSGSFDESVRIWDVK--TGKCLKTLPAHSDPVSAVHFNRDGSLIVSS 217

Query: 87  SRNGQLCLWEAS 98
           S +G   +W+ +
Sbjct: 218 SYDGLCRIWDTA 229


>BC127949-1|AAI27950.1|  314|Homo sapiens similar to hypothetical
           protein FLJ25955 protein.
          Length = 314

 Score = 92.7 bits (220), Expect = 4e-18
 Identities = 54/160 (33%), Positives = 78/160 (48%), Gaps = 4/160 (2%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H  ++   A+SPDG  ++TG  DG V  W T +G        H   V     S +   F 
Sbjct: 20  HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S+S D TVR +D+ R +  R L          V+        A+GG D   + +W ++ G
Sbjct: 80  SASCDCTVRLWDVARAKCLRVLKGHQR-SVETVSFSPDSRQLASGGWDK-RVMLWDVQSG 137

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           ++L +L GH   + S  FSPT+    LA+ SWD TVR+WD
Sbjct: 138 QMLRLLVGHRDSIQSSDFSPTVNC--LATGSWDSTVRIWD 175



 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 73/275 (26%), Positives = 119/275 (43%), Gaps = 11/275 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQL 252
           +  + ++L+TG   G  +  E     L+  L      +     SP G   A A  +   +
Sbjct: 29  FSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDC-TV 87

Query: 253 LVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHK 312
            +W+    + +   +GH   +  +++SPD   + +GG+D +V +W+  +G        H+
Sbjct: 88  RLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHR 147

Query: 313 ATVSGVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEF 369
            ++     S       + S D TVR +DL   T   + + L   S    SC+   +SG  
Sbjct: 148 DSIQSSDFSPTVNCLATGSWDSTVRIWDLRMVTPAVSHQALEGHS-GNISCLCYSASG-L 205

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            A+G  D   I +W      LL  L GH   V S+AFSP      LASA +   V++WDC
Sbjct: 206 LASGSWDK-TIHIWKPTTSSLLIQLKGHVTWVKSIAFSP--DELWLASAGYSRMVKVWDC 262

Query: 430 IDREVQCEPIRLNSD-ALQVAFRPDGEEIAVSTLD 463
              +   E ++   D A   AF PDG+ +     D
Sbjct: 263 NTGKC-LETLKGVLDVAHTCAFTPDGKILVSGAAD 296


>AL354928-6|CAI39637.1|  314|Homo sapiens WD repeat domain 38
           protein.
          Length = 314

 Score = 90.6 bits (215), Expect = 2e-17
 Identities = 53/160 (33%), Positives = 77/160 (48%), Gaps = 4/160 (2%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H  ++   A+SPDG  ++TG  DG V  W T +G        H   V     S +   F 
Sbjct: 20  HGGEVNSSAFSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFA 79

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S+S D TVR +D+ R +  R L          V+        A+GG D   + +W ++ G
Sbjct: 80  SASCDCTVRLWDVARAKCLRVLKGHQR-SVETVSFSPDSRQLASGGWDK-RVMLWDVQSG 137

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           ++L +L GH   + S  FSPT+    LA+ SWD TV +WD
Sbjct: 138 QMLRLLVGHRDSIQSSDFSPTVNC--LATGSWDSTVHIWD 175



 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 72/275 (26%), Positives = 118/275 (42%), Gaps = 11/275 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQL 252
           +  + ++L+TG   G  +  E     L+  L      +     SP G   A A  +   +
Sbjct: 29  FSPDGQMLLTGSEDGCVYGWETRSGQLLWRLGGHTGPVKFCRFSPDGHLFASASCDC-TV 87

Query: 253 LVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHK 312
            +W+    + +   +GH   +  +++SPD   + +GG+D +V +W+  +G        H+
Sbjct: 88  RLWDVARAKCLRVLKGHQRSVETVSFSPDSRQLASGGWDKRVMLWDVQSGQMLRLLVGHR 147

Query: 313 ATVSGVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEF 369
            ++     S       + S D TV  +DL   T   + + L   S    SC+   +SG  
Sbjct: 148 DSIQSSDFSPTVNCLATGSWDSTVHIWDLRMVTPAVSHQALEGHS-ANISCLCYSASG-L 205

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            A+G  D   I +W      LL  L GH   V S+AFSP      LASA +   V++WDC
Sbjct: 206 LASGSWDK-TIHIWKPTTSSLLIQLKGHVTWVKSIAFSP--DELWLASAGYSRMVKVWDC 262

Query: 430 IDREVQCEPIRLNSD-ALQVAFRPDGEEIAVSTLD 463
              +   E ++   D A   AF PDG+ +     D
Sbjct: 263 NTGKC-LETLKGVLDVAHTCAFTPDGKILVSGAAD 296


>CR457279-1|CAG33560.1|  330|Homo sapiens WDR5B protein.
          Length = 330

 Score = 89.4 bits (212), Expect = 4e-17
 Identities = 59/217 (27%), Positives = 103/217 (47%), Gaps = 6/217 (2%)

Query: 213 EMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLD 272
           E P+  L  TL      +SS+  SP G+W+A +  +   +++W     +Y     GH+L+
Sbjct: 27  ENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSAD-RLIIIWGAYDGKYEKTLYGHNLE 85

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSL 332
           ++ +A+S D   +V+   D  +K+W+  +G C  T   H   V     +      +S S 
Sbjct: 86  ISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSF 145

Query: 333 DGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLE 392
           D TV+ +++   +  +TL++ S    S V  + SG    +G  D     +W    G+ L+
Sbjct: 146 DETVKIWEVKTGKCLKTLSAHS-DPVSAVHFNCSGSLIVSGSYDGL-CRIWDAASGQCLK 203

Query: 393 VL-GGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
            L      PVS + FSP      + +A+ D T++LWD
Sbjct: 204 TLVDDDNPPVSFVKFSP--NGKYILTATLDNTLKLWD 238



 Score = 87.4 bits (207), Expect = 2e-16
 Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 9/208 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH+  ++ + +SP+G  + +   D  + +W   +G    T + H   +S V  S++    
Sbjct: 39  GHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRL 98

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS+S D T++ +D+   +  +TL   S   F C   +       +G  D   + +W +K 
Sbjct: 99  VSASDDKTLKLWDVRSGKCLKTLKGHSNYVF-CCNFNPPSNLIISGSFDE-TVKIWEVKT 156

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQ 447
           GK L+ L  H  PVS++ F+   + + + S S+DG  R+WD      QC    ++ D   
Sbjct: 157 GKCLKTLSAHSDPVSAVHFN--CSGSLIVSGSYDGLCRIWDAASG--QCLKTLVDDDNPP 212

Query: 448 VA---FRPDGEEIAVSTLDGNITFFEPS 472
           V+   F P+G+ I  +TLD  +  ++ S
Sbjct: 213 VSFVKFSPNGKYILTATLDNTLKLWDYS 240



 Score = 86.2 bits (204), Expect = 4e-16
 Identities = 55/245 (22%), Positives = 120/245 (48%), Gaps = 5/245 (2%)

Query: 186 VKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA 245
           ++++ V +  ++  LV+        L ++     + TL    + +   + +PP + I   
Sbjct: 84  LEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISG 143

Query: 246 CPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCF 305
             +   + +WE ++ + +     HS  ++ + ++  G  +V+G +DG  ++W+  +G C 
Sbjct: 144 SFD-ETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCL 202

Query: 306 VTF-HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            T   +    VS V  S N K+ ++++LD T++ +D +R R  +T T     ++   A  
Sbjct: 203 KTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANF 262

Query: 365 S--SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG 422
           S   G++  +G +D   +++W+++  ++++ L GH   V S A  PT      A+   D 
Sbjct: 263 SVTGGKWIVSGSEDNL-VYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDK 321

Query: 423 TVRLW 427
           T++LW
Sbjct: 322 TIKLW 326



 Score = 79.8 bits (188), Expect = 3e-14
 Identities = 63/282 (22%), Positives = 121/282 (42%), Gaps = 5/282 (1%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V++    + L +  +  L  +    D     TL      IS ++ S     +  A  
Sbjct: 44  VSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD 103

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           +   L +W+ +S + +   +GHS  + C  ++P    +++G FD  VK+W    G C  T
Sbjct: 104 D-KTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKT 162

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSG 367
              H   VS V  + +    VS S DG  R +D    +  +TL        S V    +G
Sbjct: 163 LSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNG 222

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR-LASASWDGTVRL 426
           ++      D   + +W    G+ L+   GH+     +  + ++T  + + S S D  V +
Sbjct: 223 KYILTATLD-NTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 281

Query: 427 WDCIDREVQCEPIRLNSD-ALQVAFRPDGEEIAVSTLDGNIT 467
           W+   +E+  + ++ ++D  +  A  P    IA + L+ + T
Sbjct: 282 WNLQTKEI-VQKLQGHTDVVISAACHPTENLIASAALENDKT 322



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 2/97 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C +++  S L+  GS D T KI  V+      + +LS H+D +  V F      +++ 
Sbjct: 128 VFCCNFNPPSNLIISGSFDETVKIWEVK--TGKCLKTLSAHSDPVSAVHFNCSGSLIVSG 185

Query: 87  SRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEG 123
           S +G   +W+A+       +  DD      V+    G
Sbjct: 186 SYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNG 222



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 394 LGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPD 453
           L GH   VSS+ FSP      LAS+S D  + +W   D + +      N +   VA+  D
Sbjct: 37  LVGHTEAVSSVKFSPN--GEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSD 94

Query: 454 GEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
              +  ++ D  +  ++  + +   +++G S+
Sbjct: 95  SSRLVSASDDKTLKLWDVRSGKCLKTLKGHSN 126


>BC043494-1|AAH43494.1|  330|Homo sapiens WD repeat domain 5B
           protein.
          Length = 330

 Score = 89.4 bits (212), Expect = 4e-17
 Identities = 59/217 (27%), Positives = 103/217 (47%), Gaps = 6/217 (2%)

Query: 213 EMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLD 272
           E P+  L  TL      +SS+  SP G+W+A +  +   +++W     +Y     GH+L+
Sbjct: 27  ENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSAD-RLIIIWGAYDGKYEKTLYGHNLE 85

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSL 332
           ++ +A+S D   +V+   D  +K+W+  +G C  T   H   V     +      +S S 
Sbjct: 86  ISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSF 145

Query: 333 DGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLE 392
           D TV+ +++   +  +TL++ S    S V  + SG    +G  D     +W    G+ L+
Sbjct: 146 DETVKIWEVKTGKCLKTLSAHS-DPVSAVHFNCSGSLIVSGSYDGL-CRIWDAASGQCLK 203

Query: 393 VL-GGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
            L      PVS + FSP      + +A+ D T++LWD
Sbjct: 204 TLVDDDNPPVSFVKFSP--NGKYILTATLDNTLKLWD 238



 Score = 87.4 bits (207), Expect = 2e-16
 Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 9/208 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH+  ++ + +SP+G  + +   D  + +W   +G    T + H   +S V  S++    
Sbjct: 39  GHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRL 98

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS+S D T++ +D+   +  +TL   S   F C   +       +G  D   + +W +K 
Sbjct: 99  VSASDDKTLKLWDVRSGKCLKTLKGHSNYVF-CCNFNPPSNLIISGSFDE-TVKIWEVKT 156

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQ 447
           GK L+ L  H  PVS++ F+   + + + S S+DG  R+WD      QC    ++ D   
Sbjct: 157 GKCLKTLSAHSDPVSAVHFN--CSGSLIVSGSYDGLCRIWDAASG--QCLKTLVDDDNPP 212

Query: 448 VA---FRPDGEEIAVSTLDGNITFFEPS 472
           V+   F P+G+ I  +TLD  +  ++ S
Sbjct: 213 VSFVKFSPNGKYILTATLDNTLKLWDYS 240



 Score = 86.2 bits (204), Expect = 4e-16
 Identities = 55/245 (22%), Positives = 120/245 (48%), Gaps = 5/245 (2%)

Query: 186 VKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA 245
           ++++ V +  ++  LV+        L ++     + TL    + +   + +PP + I   
Sbjct: 84  LEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISG 143

Query: 246 CPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCF 305
             +   + +WE ++ + +     HS  ++ + ++  G  +V+G +DG  ++W+  +G C 
Sbjct: 144 SFD-ETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCL 202

Query: 306 VTF-HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            T   +    VS V  S N K+ ++++LD T++ +D +R R  +T T     ++   A  
Sbjct: 203 KTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANF 262

Query: 365 S--SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG 422
           S   G++  +G +D   +++W+++  ++++ L GH   V S A  PT      A+   D 
Sbjct: 263 SVTGGKWIVSGSEDNL-VYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDK 321

Query: 423 TVRLW 427
           T++LW
Sbjct: 322 TIKLW 326



 Score = 79.8 bits (188), Expect = 3e-14
 Identities = 63/282 (22%), Positives = 121/282 (42%), Gaps = 5/282 (1%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V++    + L +  +  L  +    D     TL      IS ++ S     +  A  
Sbjct: 44  VSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD 103

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           +   L +W+ +S + +   +GHS  + C  ++P    +++G FD  VK+W    G C  T
Sbjct: 104 D-KTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKT 162

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSG 367
              H   VS V  + +    VS S DG  R +D    +  +TL        S V    +G
Sbjct: 163 LSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNG 222

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR-LASASWDGTVRL 426
           ++      D   + +W    G+ L+   GH+     +  + ++T  + + S S D  V +
Sbjct: 223 KYILTATLD-NTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 281

Query: 427 WDCIDREVQCEPIRLNSD-ALQVAFRPDGEEIAVSTLDGNIT 467
           W+   +E+  + ++ ++D  +  A  P    IA + L+ + T
Sbjct: 282 WNLQTKEI-VQKLQGHTDVVISAACHPTENLIASAALENDKT 322



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 2/97 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C +++  S L+  GS D T KI  V+      + +LS H+D +  V F      +++ 
Sbjct: 128 VFCCNFNPPSNLIISGSFDETVKIWEVK--TGKCLKTLSAHSDPVSAVHFNCSGSLIVSG 185

Query: 87  SRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEG 123
           S +G   +W+A+       +  DD      V+    G
Sbjct: 186 SYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNG 222



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 394 LGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPD 453
           L GH   VSS+ FSP      LAS+S D  + +W   D + +      N +   VA+  D
Sbjct: 37  LVGHTEAVSSVKFSPN--GEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSD 94

Query: 454 GEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
              +  ++ D  +  ++  + +   +++G S+
Sbjct: 95  SSRLVSASDDKTLKLWDVRSGKCLKTLKGHSN 126


>AK002149-1|BAA92110.1|  330|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11287 fis, clone PLACE1009596, weakly similar to
           VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
          Length = 330

 Score = 89.4 bits (212), Expect = 4e-17
 Identities = 59/217 (27%), Positives = 103/217 (47%), Gaps = 6/217 (2%)

Query: 213 EMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLD 272
           E P+  L  TL      +SS+  SP G+W+A +  +   +++W     +Y     GH+L+
Sbjct: 27  ENPNYALKCTLVGHTEAVSSVKFSPNGEWLASSSAD-RLIIIWGAYDGKYEKTLYGHNLE 85

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSL 332
           ++ +A+S D   +V+   D  +K+W+  +G C  T   H   V     +      +S S 
Sbjct: 86  ISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSF 145

Query: 333 DGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLE 392
           D TV+ +++   +  +TL++ S    S V  + SG    +G  D     +W    G+ L+
Sbjct: 146 DETVKIWEVKTGKCLKTLSAHS-DPVSAVHFNCSGSLIVSGSYDGL-CRIWDAASGQCLK 203

Query: 393 VL-GGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
            L      PVS + FSP      + +A+ D T++LWD
Sbjct: 204 TLVDDDNPPVSFVKFSP--NGKYILTATLDNTLKLWD 238



 Score = 87.4 bits (207), Expect = 2e-16
 Identities = 56/208 (26%), Positives = 101/208 (48%), Gaps = 9/208 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH+  ++ + +SP+G  + +   D  + +W   +G    T + H   +S V  S++    
Sbjct: 39  GHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRL 98

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS+S D T++ +D+   +  +TL   S   F C   +       +G  D   + +W +K 
Sbjct: 99  VSASDDKTLKLWDVRSGKCLKTLKGHSNYVF-CCNFNPPSNLIISGSFDE-TVKIWEVKT 156

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQ 447
           GK L+ L  H  PVS++ F+   + + + S S+DG  R+WD      QC    ++ D   
Sbjct: 157 GKCLKTLSAHSDPVSAVHFN--CSGSLIVSGSYDGLCRIWDAASG--QCLKTLVDDDNPP 212

Query: 448 VA---FRPDGEEIAVSTLDGNITFFEPS 472
           V+   F P+G+ I  +TLD  +  ++ S
Sbjct: 213 VSFVKFSPNGKYILTATLDNTLKLWDYS 240



 Score = 86.6 bits (205), Expect = 3e-16
 Identities = 55/245 (22%), Positives = 120/245 (48%), Gaps = 5/245 (2%)

Query: 186 VKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA 245
           ++++ V +  ++  LV+        L ++     + TL    + +   + +PP + I   
Sbjct: 84  LEISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISG 143

Query: 246 CPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCF 305
             +   + +WE ++ + +     HS  ++ + ++  G  +V+G +DG  ++W+  +G C 
Sbjct: 144 SFD-ETVKIWEVKTGKCLKTLSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCL 202

Query: 306 VTF-HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            T   +    VS V  S N K+ ++++LD T++ +D +R R  +T T     ++   A  
Sbjct: 203 KTLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGQKNEKYCIFANF 262

Query: 365 S--SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG 422
           S   G++  +G +D   +++W+++  ++++ L GH   V S A  PT      A+   D 
Sbjct: 263 SVTGGKWIVSGSEDNL-VYIWNLQTKEIVQKLQGHTDVVISAACHPTENLIASAALENDK 321

Query: 423 TVRLW 427
           T++LW
Sbjct: 322 TIKLW 326



 Score = 76.6 bits (180), Expect = 3e-13
 Identities = 62/282 (21%), Positives = 120/282 (42%), Gaps = 5/282 (1%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V++    + L +  +  L  +    D     TL      IS ++ S     +  A  
Sbjct: 44  VSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSDSSRLVSASD 103

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           +   L +W+ +S + +   +GHS  + C  ++P    +++G FD  VK+W    G C  T
Sbjct: 104 D-KTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKT 162

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSG 367
              H   VS V  + +    VS S DG  R +D    +  +TL        S V    +G
Sbjct: 163 LSAHSDPVSAVHFNCSGSLIVSGSYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNG 222

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR-LASASWDGTVRL 426
           ++      D   + +W    G+ L+   G +     +  + ++T  + + S S D  V +
Sbjct: 223 KYILTATLD-NTLKLWDYSRGRCLKTYTGQKNEKYCIFANFSVTGGKWIVSGSEDNLVYI 281

Query: 427 WDCIDREVQCEPIRLNSD-ALQVAFRPDGEEIAVSTLDGNIT 467
           W+   +E+  + ++ ++D  +  A  P    IA + L+ + T
Sbjct: 282 WNLQTKEI-VQKLQGHTDVVISAACHPTENLIASAALENDKT 322



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 25/97 (25%), Positives = 43/97 (44%), Gaps = 2/97 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C +++  S L+  GS D T KI  V+      + +LS H+D +  V F      +++ 
Sbjct: 128 VFCCNFNPPSNLIISGSFDETVKIWEVK--TGKCLKTLSAHSDPVSAVHFNCSGSLIVSG 185

Query: 87  SRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEG 123
           S +G   +W+A+       +  DD      V+    G
Sbjct: 186 SYDGLCRIWDAASGQCLKTLVDDDNPPVSFVKFSPNG 222



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 2/92 (2%)

Query: 394 LGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPD 453
           L GH   VSS+ FSP      LAS+S D  + +W   D + +      N +   VA+  D
Sbjct: 37  LVGHTEAVSSVKFSPN--GEWLASSSADRLIIIWGAYDGKYEKTLYGHNLEISDVAWSSD 94

Query: 454 GEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
              +  ++ D  +  ++  + +   +++G S+
Sbjct: 95  SSRLVSASDDKTLKLWDVRSGKCLKTLKGHSN 126


>M36429-1|AAA63264.1|  340|Homo sapiens protein ( Human transducin
           beta-2 subunit mRNA, complete cds. ).
          Length = 340

 Score = 88.6 bits (210), Expect = 7e-17
 Identities = 51/176 (28%), Positives = 84/176 (47%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q  +   GHS D+  L+ +PDG   V+G  D  +K+W+  +  C  TF  H++
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V    N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   +W    G    VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNIWDAMKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            F     LD     Y L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+ G+      GH   V SL+ +P        S + D +++LWD  D   +   I  
Sbjct: 169 -WDIETGQQTVGFAGHSGDVMSLSLAPD--GRTFVSGACDASIKLWDVRDSMCRQTFIGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   VAF P+G      + D     F+
Sbjct: 226 ESDINAVAFFPNGYAFTTGSDDATCRLFD 254



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 49/251 (19%), Positives = 111/251 (44%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   ++T   D    +W+   G 
Sbjct: 117 LDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN-QIITSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             V F  H   V  ++ + + + FVS + D +++ +D+      +T         + VA 
Sbjct: 176 QTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE-SDINAVAF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +    G D     ++ ++  + L ++  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFS---RSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNIWDAM 300


>M16514-1|AAA03179.1|  340|Homo sapiens GNB2 protein.
          Length = 340

 Score = 88.6 bits (210), Expect = 7e-17
 Identities = 51/176 (28%), Positives = 84/176 (47%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q  +   GHS D+  L+ +PDG   V+G  D  +K+W+  +  C  TF  H++
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V    N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   +W    G    VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNIWDAMKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            F     LD     Y L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+ G+      GH   V SL+ +P        S + D +++LWD  D   +   I  
Sbjct: 169 -WDIETGQQTVGFAGHSGDVMSLSLAPD--GRTFVSGACDASIKLWDVRDSMCRQTFIGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   VAF P+G      + D     F+
Sbjct: 226 ESDINAVAFFPNGYAFTTGSDDATCRLFD 254



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 49/251 (19%), Positives = 111/251 (44%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   ++T   D    +W+   G 
Sbjct: 117 LDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN-QIITSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             V F  H   V  ++ + + + FVS + D +++ +D+      +T         + VA 
Sbjct: 176 QTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE-SDINAVAF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +    G D     ++ ++  + L ++  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFS---RSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNIWDAM 300


>CR541729-1|CAG46530.1|  340|Homo sapiens GNB2 protein.
          Length = 340

 Score = 88.6 bits (210), Expect = 7e-17
 Identities = 51/176 (28%), Positives = 84/176 (47%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q  +   GHS D+  L+ +PDG   V+G  D  +K+W+  +  C  TF  H++
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V    N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   +W    G    VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNIWDAMKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            F     LD     Y L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+ G+      GH   V SL+ +P        S + D +++LWD  D   +   I  
Sbjct: 169 -WDIETGQQTVGFAGHSGDVMSLSLAPD--GRTFVSGACDASIKLWDVRDSMCRQTFIGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   VAF P+G      + D     F+
Sbjct: 226 ESDINAVAFFPNGYAFTTGSDDATCRLFD 254



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 49/251 (19%), Positives = 111/251 (44%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   ++T   D    +W+   G 
Sbjct: 117 LDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN-QIITSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             V F  H   V  ++ + + + FVS + D +++ +D+      +T         + VA 
Sbjct: 176 QTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE-SDINAVAF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +    G D     ++ ++  + L ++  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFS---RSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNIWDAM 300


>BC068003-1|AAH68003.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2 protein.
          Length = 340

 Score = 88.6 bits (210), Expect = 7e-17
 Identities = 51/176 (28%), Positives = 84/176 (47%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q  +   GHS D+  L+ +PDG   V+G  D  +K+W+  +  C  TF  H++
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V    N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   +W    G    VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNIWDAMKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            F     LD     Y L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+ G+      GH   V SL+ +P        S + D +++LWD  D   +   I  
Sbjct: 169 -WDIETGQQTVGFAGHSGDVMSLSLAPD--GRTFVSGACDASIKLWDVRDSMCRQTFIGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   VAF P+G      + D     F+
Sbjct: 226 ESDINAVAFFPNGYAFTTGSDDATCRLFD 254



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 49/251 (19%), Positives = 111/251 (44%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   ++T   D    +W+   G 
Sbjct: 117 LDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN-QIITSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             V F  H   V  ++ + + + FVS + D +++ +D+      +T         + VA 
Sbjct: 176 QTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE-SDINAVAF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +    G D     ++ ++  + L ++  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFS---RSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNIWDAM 300


>BC012348-1|AAH12348.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2 protein.
          Length = 340

 Score = 88.6 bits (210), Expect = 7e-17
 Identities = 51/176 (28%), Positives = 84/176 (47%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q  +   GHS D+  L+ +PDG   V+G  D  +K+W+  +  C  TF  H++
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V    N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   +W    G    VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNIWDAMKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            F     LD     Y L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+ G+      GH   V SL+ +P        S + D +++LWD  D   +   I  
Sbjct: 169 -WDIETGQQTVGFAGHSGDVMSLSLAPD--GRTFVSGACDASIKLWDVRDSMCRQTFIGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   VAF P+G      + D     F+
Sbjct: 226 ESDINAVAFFPNGYAFTTGSDDATCRLFD 254



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 49/251 (19%), Positives = 111/251 (44%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   ++T   D    +W+   G 
Sbjct: 117 LDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN-QIITSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             V F  H   V  ++ + + + FVS + D +++ +D+      +T         + VA 
Sbjct: 176 QTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE-SDINAVAF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +    G D     ++ ++  + L ++  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFS---RSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNIWDAM 300


>BC010073-1|AAH10073.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2 protein.
          Length = 340

 Score = 88.6 bits (210), Expect = 7e-17
 Identities = 51/176 (28%), Positives = 84/176 (47%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q  +   GHS D+  L+ +PDG   V+G  D  +K+W+  +  C  TF  H++
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V    N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   +W    G    VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNIWDAMKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            F     LD     Y L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+ G+      GH   V SL+ +P        S + D +++LWD  D   +   I  
Sbjct: 169 -WDIETGQQTVGFAGHSGDVMSLSLAPD--GRTFVSGACDASIKLWDVRDSMCRQTFIGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   VAF P+G      + D     F+
Sbjct: 226 ESDINAVAFFPNGYAFTTGSDDATCRLFD 254



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 49/251 (19%), Positives = 111/251 (44%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   ++T   D    +W+   G 
Sbjct: 117 LDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN-QIITSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             V F  H   V  ++ + + + FVS + D +++ +D+      +T         + VA 
Sbjct: 176 QTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE-SDINAVAF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +    G D     ++ ++  + L ++  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFS---RSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNIWDAM 300


>AF501883-1|AAM15919.1|  340|Homo sapiens guanine nucleotide binding
           protein beta 2 protein.
          Length = 340

 Score = 88.6 bits (210), Expect = 7e-17
 Identities = 51/176 (28%), Positives = 84/176 (47%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q  +   GHS D+  L+ +PDG   V+G  D  +K+W+  +  C  TF  H++
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V    N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   +W    G    VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNIWDAMKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            F     LD     Y L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+ G+      GH   V SL+ +P        S + D +++LWD  D   +   I  
Sbjct: 169 -WDIETGQQTVGFAGHSGDVMSLSLAPD--GRTFVSGACDASIKLWDVRDSMCRQTFIGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   VAF P+G      + D     F+
Sbjct: 226 ESDINAVAFFPNGYAFTTGSDDATCRLFD 254



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 49/251 (19%), Positives = 111/251 (44%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   ++T   D    +W+   G 
Sbjct: 117 LDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN-QIITSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             V F  H   V  ++ + + + FVS + D +++ +D+      +T         + VA 
Sbjct: 176 QTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE-SDINAVAF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +    G D     ++ ++  + L ++  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFS---RSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNIWDAM 300


>AF053356-4|AAC78794.1|  340|Homo sapiens GNB2 protein.
          Length = 340

 Score = 88.6 bits (210), Expect = 7e-17
 Identities = 51/176 (28%), Positives = 84/176 (47%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q  +   GHS D+  L+ +PDG   V+G  D  +K+W+  +  C  TF  H++
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V    N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   +W    G    VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNIWDAMKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 55.2 bits (127), Expect = 8e-07
 Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            F     LD     Y L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+ G+      GH   V SL+ +P        S + D +++LWD  D   +   I  
Sbjct: 169 -WDIETGQQTVGFAGHSGDVMSLSLAPD--GRTFVSGACDASIKLWDVRDSMCRQTFIGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   VAF P+G      + D     F+
Sbjct: 226 ESDINAVAFFPNGYAFTTGSDDATCRLFD 254



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 49/251 (19%), Positives = 111/251 (44%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   ++T   D    +W+   G 
Sbjct: 117 LDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN-QIITSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             V F  H   V  ++ + + + FVS + D +++ +D+      +T         + VA 
Sbjct: 176 QTVGFAGHSGDVMSLSLAPDGRTFVSGACDASIKLWDVRDSMCRQTFIGHE-SDINAVAF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +    G D     ++ ++  + L ++  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFS---RSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNIWDAM 300


>M16538-1|AAA35922.1|  340|Homo sapiens protein ( Human
           signal-transducing guanine nucleotide-binding regulatory
           (G) protein beta subunit mRNA, complete cds. ).
          Length = 340

 Score = 86.6 bits (205), Expect = 3e-16
 Identities = 50/176 (28%), Positives = 84/176 (47%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q  +   GHS D+  L+ +P+G   V+G  D  +K+W+  +  C  TF  H++
Sbjct: 168 LWDIETGQQTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V    N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVAFFPNGYAFTTGSDDATCRLFDLRADQELLMYSHDNIICGITSVAFSRSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   +W    G    VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNIWDAMKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 51/209 (24%), Positives = 77/209 (36%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAXSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            F     LD     Y L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -FVACGGLDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDNQIITSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+ G+      GH   V SL+ +P        S + D +++LWD  D   +   I  
Sbjct: 169 -WDIETGQQTVGFAGHSGDVMSLSLAPN--GRTFVSGACDASIKLWDVRDSMCRQTFIGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   VAF P+G      + D     F+
Sbjct: 226 ESDINAVAFFPNGYAFTTGSDDATCRLFD 254



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 49/251 (19%), Positives = 110/251 (43%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +  G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAXSGNFVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   ++T   D    +W+   G 
Sbjct: 117 LDNICSIYSLKTREGNVRVSRELPGHTGYLSCCRFLDDN-QIITSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
             V F  H   V  ++ + N + FVS + D +++ +D+      +T         + VA 
Sbjct: 176 QTVGFAGHSGDVMSLSLAPNGRTFVSGACDASIKLWDVRDSMCRQTFIGHE-SDINAVAF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +    G D     ++ ++  + L ++  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFTTGSDDATCRLFDLRADQEL-LMYSHDNIICGITSVAFS---RSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNIWDAM 300


>BC000873-1|AAH00873.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 4 protein.
          Length = 340

 Score = 85.8 bits (203), Expect = 5e-16
 Identities = 53/176 (30%), Positives = 82/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GHS D+  L+ SPD    V+G  D   K+W+  +G C  +F  H +
Sbjct: 168 LWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVS 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V+   N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW    G    VL GH+  VS L    T     +A+ SWD  +R+W+
Sbjct: 288 GYDD-FNCNVWDTLKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLRIWN 340



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/251 (20%), Positives = 112/251 (44%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+     
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDS-QIVTSSGDTTCALWDIETAQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ S + + FVS + D + + +D+ R    R   +  +   + V+ 
Sbjct: 176 QTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDI-RDGMCRQSFTGHVSDINAVSF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +  A G D     ++ ++  + L +L  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFATGSDDATCRLFDLRADQEL-LLYSHDNIICGITSVAFS---KSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNVWDTL 300



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 49/209 (23%), Positives = 78/209 (37%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+  +      GH   V SL+ SP + +    S + D + +LWD  D   +      
Sbjct: 169 -WDIETAQQTTTFTGHSGDVMSLSLSPDMRT--FVSGACDASSKLWDIRDGMCRQSFTGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   V+F P+G   A  + D     F+
Sbjct: 226 VSDINAVSFFPNGYAFATGSDDATCRLFD 254


>AF300648-1|AAG18442.1|  340|Homo sapiens guanine nucleotide binding
           protein beta subunit 4 protein.
          Length = 340

 Score = 85.8 bits (203), Expect = 5e-16
 Identities = 53/176 (30%), Positives = 82/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GHS D+  L+ SPD    V+G  D   K+W+  +G C  +F  H +
Sbjct: 168 LWDIETAQQTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDIRDGMCRQSFTGHVS 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ V+   N   F + S D T R +DL   +     +  +++   + VA   SG    A
Sbjct: 228 DINAVSFFPNGYAFATGSDDATCRLFDLRADQELLLYSHDNIICGITSVAFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW    G    VL GH+  VS L    T     +A+ SWD  +R+W+
Sbjct: 288 GYDD-FNCNVWDTLKGDRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLRIWN 340



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/251 (20%), Positives = 112/251 (44%), Gaps = 14/251 (5%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+     
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDS-QIVTSSGDTTCALWDIETAQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ S + + FVS + D + + +D+ R    R   +  +   + V+ 
Sbjct: 176 QTTTFTGHSGDVMSLSLSPDMRTFVSGACDASSKLWDI-RDGMCRQSFTGHVSDINAVSF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE---APVSSLAFSPTLTSTRLASASW 420
             +G +  A G D     ++ ++  + L +L  H+     ++S+AFS    S RL  A +
Sbjct: 235 FPNG-YAFATGSDDATCRLFDLRADQEL-LLYSHDNIICGITSVAFS---KSGRLLLAGY 289

Query: 421 DG-TVRLWDCI 430
           D     +WD +
Sbjct: 290 DDFNCNVWDTL 300



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 49/209 (23%), Positives = 78/209 (37%), Gaps = 11/209 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGYDSRLLVSASQDGKLIIWDSYTTNKMHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTLTS-PSLVQF-SCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     P    + SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCRFLDDSQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL 441
            W I+  +      GH   V SL+ SP + +    S + D + +LWD  D   +      
Sbjct: 169 -WDIETAQQTTTFTGHSGDVMSLSLSPDMRT--FVSGACDASSKLWDIRDGMCRQSFTGH 225

Query: 442 NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
            SD   V+F P+G   A  + D     F+
Sbjct: 226 VSDINAVSFFPNGYAFATGSDDATCRLFD 254


>X95525-1|CAA64777.1|  799|Homo sapiens hTAFII100 protein.
          Length = 799

 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 6/204 (2%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GHS  +   ++SPD  ++++   DG V++W+     C V +  H   V     S    +F
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS   D   R +    Y+  R + +  L   +C     +  + A G  D   + +W +  
Sbjct: 601 VSGGHDRVARLWATDHYQPLR-IFAGHLADVNCTRFHPNSNYVATGSAD-RTVRLWDVLN 658

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL- 446
           G  + +  GH+ P+ SL FSP      LA+ + DG V LWD I   +    ++ ++D + 
Sbjct: 659 GNCVRIFTGHKGPIHSLTFSP--NGRFLATGATDGRVLLWD-IGHGLMVGELKGHTDTVC 715

Query: 447 QVAFRPDGEEIAVSTLDGNITFFE 470
            + F  DGE +A  ++D  +  ++
Sbjct: 716 SLRFSRDGEILASGSMDNTVRLWD 739



 Score = 82.2 bits (194), Expect = 6e-15
 Identities = 58/197 (29%), Positives = 88/197 (44%), Gaps = 5/197 (2%)

Query: 234 SVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGK 293
           S SP  +++  +  + G + +W  Q+   ++  +GH+  +    +SP G + V+GG D  
Sbjct: 550 SFSPDRNYLLSSSED-GTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRV 608

Query: 294 VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSP 353
            ++W T +      F  H A V+      N  +  + S D TVR +D+      R  T  
Sbjct: 609 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGH 668

Query: 354 SLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTST 413
                  +    +G F A G  D   + +W I  G ++  L GH   V SL FS      
Sbjct: 669 K-GPIHSLTFSPNGRFLATGATD-GRVLLWDIGHGLMVGELKGHTDTVCSLRFS--RDGE 724

Query: 414 RLASASWDGTVRLWDCI 430
            LAS S D TVRLWD I
Sbjct: 725 ILASGSMDNTVRLWDAI 741



 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 4/175 (2%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H   V G + S ++ + +SSS DGTVR + L  +         +   +        G + 
Sbjct: 542 HSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWD-TQFSPYGYYF 600

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
            +GG D     +W+    + L +  GH A V+   F P   S  +A+ S D TVRLWD +
Sbjct: 601 VSGGHDRVAR-LWATDHYQPLRIFAGHLADVNCTRFHPN--SNYVATGSADRTVRLWDVL 657

Query: 431 DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
           +                + F P+G  +A    DG +  ++       G ++G +D
Sbjct: 658 NGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTD 712



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/116 (22%), Positives = 57/116 (49%), Gaps = 1/116 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +   ++H  +  + TG +     L ++ + N +   +  +  I S++ SP G ++A    
Sbjct: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
           + G++L+W+      V + +GH+  +  L +S DG  + +G  D  V++W+    F
Sbjct: 690 D-GRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAF 744



 Score = 40.3 bits (90), Expect = 0.024
 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 15/124 (12%)

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           CF TF      ++ V  + +         D TVR + +T  +  R++   S    S +  
Sbjct: 462 CFYTFLNVYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQAS--DLSLIDK 518

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
           +S          DV E  +   K    L++L GH  PV   +FSP      L S+S DGT
Sbjct: 519 ESD---------DVLER-IMDEKTASELKILYGHSGPVYGASFSP--DRNYLLSSSEDGT 566

Query: 424 VRLW 427
           VRLW
Sbjct: 567 VRLW 570



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 5/89 (5%)

Query: 8   TGEYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGH 67
           T  Y+P    R+F   L +V C  +   S  +A GS D T ++  V  L    +   +GH
Sbjct: 614 TDHYQPL---RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV--LNGNCVRIFTGH 668

Query: 68  TDKIIGVFFERKSLDLITVSRNGQLCLWE 96
              I  + F      L T + +G++ LW+
Sbjct: 669 KGPIHSLTFSPNGRFLATGATDGRVLLWD 697



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 3/102 (2%)

Query: 18  RVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFE 77
           R+F      +  L +S   R LA G+ D    +  + +   + +  L GHTD +  + F 
Sbjct: 663 RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH--GLMVGELKGHTDTVCSLRFS 720

Query: 78  RKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRL 119
           R    L + S +  + LW+A I A E     D T+    + L
Sbjct: 721 RDGEILASGSMDNTVRLWDA-IKAFEDLETDDFTTATGHINL 761


>U80191-1|AAC51215.1|  800|Homo sapiens TFIID subunit TAFII100
           protein.
          Length = 800

 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 6/204 (2%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GHS  +   ++SPD  ++++   DG V++W+     C V +  H   V     S    +F
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS   D   R +    Y+  R + +  L   +C     +  + A G  D   + +W +  
Sbjct: 601 VSGGHDRVARLWATDHYQPLR-IFAGHLADVNCTRFHPNSNYVATGSAD-RTVRLWDVLN 658

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL- 446
           G  + +  GH+ P+ SL FSP      LA+ + DG V LWD I   +    ++ ++D + 
Sbjct: 659 GNCVRIFTGHKGPIHSLTFSP--NGRFLATGATDGRVLLWD-IGHGLMVGELKGHTDTVC 715

Query: 447 QVAFRPDGEEIAVSTLDGNITFFE 470
            + F  DGE +A  ++D  +  ++
Sbjct: 716 SLRFSRDGEILASGSMDNTVRLWD 739



 Score = 82.2 bits (194), Expect = 6e-15
 Identities = 58/197 (29%), Positives = 88/197 (44%), Gaps = 5/197 (2%)

Query: 234 SVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGK 293
           S SP  +++  +  + G + +W  Q+   ++  +GH+  +    +SP G + V+GG D  
Sbjct: 550 SFSPDRNYLLSSSED-GTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRV 608

Query: 294 VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSP 353
            ++W T +      F  H A V+      N  +  + S D TVR +D+      R  T  
Sbjct: 609 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGH 668

Query: 354 SLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTST 413
                  +    +G F A G  D   + +W I  G ++  L GH   V SL FS      
Sbjct: 669 K-GPIHSLTFSPNGRFLATGATD-GRVLLWDIGHGLMVGELKGHTDTVCSLRFS--RDGE 724

Query: 414 RLASASWDGTVRLWDCI 430
            LAS S D TVRLWD I
Sbjct: 725 ILASGSMDNTVRLWDAI 741



 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 4/175 (2%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H   V G + S ++ + +SSS DGTVR + L  +         +   +        G + 
Sbjct: 542 HSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWD-TQFSPYGYYF 600

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
            +GG D     +W+    + L +  GH A V+   F P   S  +A+ S D TVRLWD +
Sbjct: 601 VSGGHDRVAR-LWATDHYQPLRIFAGHLADVNCTRFHPN--SNYVATGSADRTVRLWDVL 657

Query: 431 DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
           +                + F P+G  +A    DG +  ++       G ++G +D
Sbjct: 658 NGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTD 712



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/116 (22%), Positives = 57/116 (49%), Gaps = 1/116 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +   ++H  +  + TG +     L ++ + N +   +  +  I S++ SP G ++A    
Sbjct: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
           + G++L+W+      V + +GH+  +  L +S DG  + +G  D  V++W+    F
Sbjct: 690 D-GRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAF 744



 Score = 40.7 bits (91), Expect = 0.018
 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 15/124 (12%)

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           CF TF      ++ V  + +         D TVR + +T  +  R++   S    S +  
Sbjct: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQAS--DLSLIDK 518

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
           +S          DV E  +   K    L++L GH  PV   +FSP      L S+S DGT
Sbjct: 519 ESD---------DVLER-IMDEKTASELKILYGHSGPVYGASFSP--DRNYLLSSSEDGT 566

Query: 424 VRLW 427
           VRLW
Sbjct: 567 VRLW 570



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 5/89 (5%)

Query: 8   TGEYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGH 67
           T  Y+P    R+F   L +V C  +   S  +A GS D T ++  V  L    +   +GH
Sbjct: 614 TDHYQPL---RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV--LNGNCVRIFTGH 668

Query: 68  TDKIIGVFFERKSLDLITVSRNGQLCLWE 96
              I  + F      L T + +G++ LW+
Sbjct: 669 KGPIHSLTFSPNGRFLATGATDGRVLLWD 697



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 3/102 (2%)

Query: 18  RVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFE 77
           R+F      +  L +S   R LA G+ D    +  + +   + +  L GHTD +  + F 
Sbjct: 663 RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH--GLMVGELKGHTDTVCSLRFS 720

Query: 78  RKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRL 119
           R    L + S +  + LW+A I A E     D T+    + L
Sbjct: 721 RDGEILASGSMDNTVRLWDA-IKAFEDLETDDFTTATGHINL 761


>U75309-1|AAC50902.1|  801|Homo sapiens TBP-associated factor
           protein.
          Length = 801

 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 6/204 (2%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GHS  +   ++SPD  ++++   DG V++W+     C V +  H   V     S    +F
Sbjct: 542 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 601

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS   D   R +    Y+  R + +  L   +C     +  + A G  D   + +W +  
Sbjct: 602 VSGGHDRVARLWATDHYQPLR-IFAGHLADVNCTRFHPNSNYVATGSAD-RTVRLWDVLN 659

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL- 446
           G  + +  GH+ P+ SL FSP      LA+ + DG V LWD I   +    ++ ++D + 
Sbjct: 660 GNCVRIFTGHKGPIHSLTFSP--NGRFLATGATDGRVLLWD-IGHGLMVGELKGHTDTVC 716

Query: 447 QVAFRPDGEEIAVSTLDGNITFFE 470
            + F  DGE +A  ++D  +  ++
Sbjct: 717 SLRFSRDGEILASGSMDNTVRLWD 740



 Score = 82.2 bits (194), Expect = 6e-15
 Identities = 58/197 (29%), Positives = 88/197 (44%), Gaps = 5/197 (2%)

Query: 234 SVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGK 293
           S SP  +++  +  + G + +W  Q+   ++  +GH+  +    +SP G + V+GG D  
Sbjct: 551 SFSPDRNYLLSSSED-GTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRV 609

Query: 294 VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSP 353
            ++W T +      F  H A V+      N  +  + S D TVR +D+      R  T  
Sbjct: 610 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGH 669

Query: 354 SLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTST 413
                  +    +G F A G  D   + +W I  G ++  L GH   V SL FS      
Sbjct: 670 K-GPIHSLTFSPNGRFLATGATD-GRVLLWDIGHGLMVGELKGHTDTVCSLRFS--RDGE 725

Query: 414 RLASASWDGTVRLWDCI 430
            LAS S D TVRLWD I
Sbjct: 726 ILASGSMDNTVRLWDAI 742



 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 4/175 (2%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H   V G + S ++ + +SSS DGTVR + L  +         +   +        G + 
Sbjct: 543 HSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWD-TQFSPYGYYF 601

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
            +GG D     +W+    + L +  GH A V+   F P   S  +A+ S D TVRLWD +
Sbjct: 602 VSGGHDRVAR-LWATDHYQPLRIFAGHLADVNCTRFHPN--SNYVATGSADRTVRLWDVL 658

Query: 431 DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
           +                + F P+G  +A    DG +  ++       G ++G +D
Sbjct: 659 NGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTD 713



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/116 (22%), Positives = 57/116 (49%), Gaps = 1/116 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +   ++H  +  + TG +     L ++ + N +   +  +  I S++ SP G ++A    
Sbjct: 631 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 690

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
           + G++L+W+      V + +GH+  +  L +S DG  + +G  D  V++W+    F
Sbjct: 691 D-GRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAF 745



 Score = 40.7 bits (91), Expect = 0.018
 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 15/124 (12%)

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           CF TF      ++ V  + +         D TVR + +T  +  R++   S    S +  
Sbjct: 463 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQAS--DLSLIDK 519

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
           +S          DV E  +   K    L++L GH  PV   +FSP      L S+S DGT
Sbjct: 520 ESD---------DVLER-IMDEKTASELKILYGHSGPVYGASFSP--DRNYLLSSSEDGT 567

Query: 424 VRLW 427
           VRLW
Sbjct: 568 VRLW 571



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 5/89 (5%)

Query: 8   TGEYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGH 67
           T  Y+P    R+F   L +V C  +   S  +A GS D T ++  V  L    +   +GH
Sbjct: 615 TDHYQPL---RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV--LNGNCVRIFTGH 669

Query: 68  TDKIIGVFFERKSLDLITVSRNGQLCLWE 96
              I  + F      L T + +G++ LW+
Sbjct: 670 KGPIHSLTFSPNGRFLATGATDGRVLLWD 698



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 3/102 (2%)

Query: 18  RVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFE 77
           R+F      +  L +S   R LA G+ D    +  + +   + +  L GHTD +  + F 
Sbjct: 664 RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH--GLMVGELKGHTDTVCSLRFS 721

Query: 78  RKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRL 119
           R    L + S +  + LW+A I A E     D T+    + L
Sbjct: 722 RDGEILASGSMDNTVRLWDA-IKAFEDLETDDFTTATGHINL 762


>BC052268-1|AAH52268.2|  800|Homo sapiens TAF5 RNA polymerase II,
           TATA box binding protein (TBP)-associated factor, 100kD
           protein.
          Length = 800

 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 6/204 (2%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GHS  +   ++SPD  ++++   DG V++W+     C V +  H   V     S    +F
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS   D   R +    Y+  R + +  L   +C     +  + A G  D   + +W +  
Sbjct: 601 VSGGHDRVARLWATDHYQPLR-IFAGHLADVNCTRFHPNSNYVATGSAD-RTVRLWDVLN 658

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL- 446
           G  + +  GH+ P+ SL FSP      LA+ + DG V LWD I   +    ++ ++D + 
Sbjct: 659 GNCVRIFTGHKGPIHSLTFSP--NGRFLATGATDGRVLLWD-IGHGLMVGELKGHTDTVC 715

Query: 447 QVAFRPDGEEIAVSTLDGNITFFE 470
            + F  DGE +A  ++D  +  ++
Sbjct: 716 SLRFSRDGEILASGSMDNTVRLWD 739



 Score = 82.2 bits (194), Expect = 6e-15
 Identities = 58/197 (29%), Positives = 88/197 (44%), Gaps = 5/197 (2%)

Query: 234 SVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGK 293
           S SP  +++  +  + G + +W  Q+   ++  +GH+  +    +SP G + V+GG D  
Sbjct: 550 SFSPDRNYLLSSSED-GTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRV 608

Query: 294 VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSP 353
            ++W T +      F  H A V+      N  +  + S D TVR +D+      R  T  
Sbjct: 609 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGH 668

Query: 354 SLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTST 413
                  +    +G F A G  D   + +W I  G ++  L GH   V SL FS      
Sbjct: 669 K-GPIHSLTFSPNGRFLATGATD-GRVLLWDIGHGLMVGELKGHTDTVCSLRFS--RDGE 724

Query: 414 RLASASWDGTVRLWDCI 430
            LAS S D TVRLWD I
Sbjct: 725 ILASGSMDNTVRLWDAI 741



 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 4/175 (2%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H   V G + S ++ + +SSS DGTVR + L  +         +   +        G + 
Sbjct: 542 HSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWD-TQFSPYGYYF 600

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
            +GG D     +W+    + L +  GH A V+   F P   S  +A+ S D TVRLWD +
Sbjct: 601 VSGGHDRVAR-LWATDHYQPLRIFAGHLADVNCTRFHPN--SNYVATGSADRTVRLWDVL 657

Query: 431 DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
           +                + F P+G  +A    DG +  ++       G ++G +D
Sbjct: 658 NGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTD 712



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/116 (22%), Positives = 57/116 (49%), Gaps = 1/116 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +   ++H  +  + TG +     L ++ + N +   +  +  I S++ SP G ++A    
Sbjct: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
           + G++L+W+      V + +GH+  +  L +S DG  + +G  D  V++W+    F
Sbjct: 690 D-GRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAF 744



 Score = 40.7 bits (91), Expect = 0.018
 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 15/124 (12%)

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           CF TF      ++ V  + +         D TVR + +T  +  R++   S    S +  
Sbjct: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQAS--DLSLIDK 518

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
           +S          DV E  +   K    L++L GH  PV   +FSP      L S+S DGT
Sbjct: 519 ESD---------DVLER-IMDEKTASELKILYGHSGPVYGASFSP--DRNYLLSSSEDGT 566

Query: 424 VRLW 427
           VRLW
Sbjct: 567 VRLW 570



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 5/89 (5%)

Query: 8   TGEYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGH 67
           T  Y+P    R+F   L +V C  +   S  +A GS D T ++  V  L    +   +GH
Sbjct: 614 TDHYQPL---RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV--LNGNCVRIFTGH 668

Query: 68  TDKIIGVFFERKSLDLITVSRNGQLCLWE 96
              I  + F      L T + +G++ LW+
Sbjct: 669 KGPIHSLTFSPNGRFLATGATDGRVLLWD 697



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 3/102 (2%)

Query: 18  RVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFE 77
           R+F      +  L +S   R LA G+ D    +  + +   + +  L GHTD +  + F 
Sbjct: 663 RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH--GLMVGELKGHTDTVCSLRFS 720

Query: 78  RKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRL 119
           R    L + S +  + LW+A I A E     D T+    + L
Sbjct: 721 RDGEILASGSMDNTVRLWDA-IKAFEDLETDDFTTATGHINL 761


>AL591408-4|CAI16747.1|  800|Homo sapiens TAF5 RNA polymerase II,
           TATA box binding protein (TBP)-associated factor, 100kD
           protein.
          Length = 800

 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 6/204 (2%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GHS  +   ++SPD  ++++   DG V++W+     C V +  H   V     S    +F
Sbjct: 541 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 600

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS   D   R +    Y+  R + +  L   +C     +  + A G  D   + +W +  
Sbjct: 601 VSGGHDRVARLWATDHYQPLR-IFAGHLADVNCTRFHPNSNYVATGSAD-RTVRLWDVLN 658

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL- 446
           G  + +  GH+ P+ SL FSP      LA+ + DG V LWD I   +    ++ ++D + 
Sbjct: 659 GNCVRIFTGHKGPIHSLTFSP--NGRFLATGATDGRVLLWD-IGHGLMVGELKGHTDTVC 715

Query: 447 QVAFRPDGEEIAVSTLDGNITFFE 470
            + F  DGE +A  ++D  +  ++
Sbjct: 716 SLRFSRDGEILASGSMDNTVRLWD 739



 Score = 82.2 bits (194), Expect = 6e-15
 Identities = 58/197 (29%), Positives = 88/197 (44%), Gaps = 5/197 (2%)

Query: 234 SVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGK 293
           S SP  +++  +  + G + +W  Q+   ++  +GH+  +    +SP G + V+GG D  
Sbjct: 550 SFSPDRNYLLSSSED-GTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRV 608

Query: 294 VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSP 353
            ++W T +      F  H A V+      N  +  + S D TVR +D+      R  T  
Sbjct: 609 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGH 668

Query: 354 SLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTST 413
                  +    +G F A G  D   + +W I  G ++  L GH   V SL FS      
Sbjct: 669 K-GPIHSLTFSPNGRFLATGATD-GRVLLWDIGHGLMVGELKGHTDTVCSLRFS--RDGE 724

Query: 414 RLASASWDGTVRLWDCI 430
            LAS S D TVRLWD I
Sbjct: 725 ILASGSMDNTVRLWDAI 741



 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 4/175 (2%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H   V G + S ++ + +SSS DGTVR + L  +         +   +        G + 
Sbjct: 542 HSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWD-TQFSPYGYYF 600

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
            +GG D     +W+    + L +  GH A V+   F P   S  +A+ S D TVRLWD +
Sbjct: 601 VSGGHDRVAR-LWATDHYQPLRIFAGHLADVNCTRFHPN--SNYVATGSADRTVRLWDVL 657

Query: 431 DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
           +                + F P+G  +A    DG +  ++       G ++G +D
Sbjct: 658 NGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTD 712



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/116 (22%), Positives = 57/116 (49%), Gaps = 1/116 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +   ++H  +  + TG +     L ++ + N +   +  +  I S++ SP G ++A    
Sbjct: 630 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 689

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
           + G++L+W+      V + +GH+  +  L +S DG  + +G  D  V++W+    F
Sbjct: 690 D-GRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAF 744



 Score = 40.7 bits (91), Expect = 0.018
 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 15/124 (12%)

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           CF TF      ++ V  + +         D TVR + +T  +  R++   S    S +  
Sbjct: 462 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQAS--DLSLIDK 518

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
           +S          DV E  +   K    L++L GH  PV   +FSP      L S+S DGT
Sbjct: 519 ESD---------DVLER-IMDEKTASELKILYGHSGPVYGASFSP--DRNYLLSSSEDGT 566

Query: 424 VRLW 427
           VRLW
Sbjct: 567 VRLW 570



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 5/89 (5%)

Query: 8   TGEYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGH 67
           T  Y+P    R+F   L +V C  +   S  +A GS D T ++  V  L    +   +GH
Sbjct: 614 TDHYQPL---RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV--LNGNCVRIFTGH 668

Query: 68  TDKIIGVFFERKSLDLITVSRNGQLCLWE 96
              I  + F      L T + +G++ LW+
Sbjct: 669 KGPIHSLTFSPNGRFLATGATDGRVLLWD 697



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 3/102 (2%)

Query: 18  RVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFE 77
           R+F      +  L +S   R LA G+ D    +  + +   + +  L GHTD +  + F 
Sbjct: 663 RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH--GLMVGELKGHTDTVCSLRFS 720

Query: 78  RKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRL 119
           R    L + S +  + LW+A I A E     D T+    + L
Sbjct: 721 RDGEILASGSMDNTVRLWDA-IKAFEDLETDDFTTATGHINL 761


>AK223615-1|BAD97335.1|  803|Homo sapiens Transcription initiation
           factor TFIID subunit 5 variant protein.
          Length = 803

 Score = 85.0 bits (201), Expect = 9e-16
 Identities = 53/204 (25%), Positives = 94/204 (46%), Gaps = 6/204 (2%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GHS  +   ++SPD  ++++   DG V++W+     C V +  H   V     S    +F
Sbjct: 544 GHSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYF 603

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS   D   R +    Y+  R + +  L   +C     +  + A G  D   + +W +  
Sbjct: 604 VSGGHDRVARLWATDHYQPLR-IFAGHLADVNCTRFHPNSNYVATGSAD-RTVRLWDVLN 661

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL- 446
           G  + +  GH+ P+ SL FSP      LA+ + DG V LWD I   +    ++ ++D + 
Sbjct: 662 GNCVRIFTGHKGPIHSLTFSP--NGRFLATGATDGRVLLWD-IGHGLMVGELKGHTDTVC 718

Query: 447 QVAFRPDGEEIAVSTLDGNITFFE 470
            + F  DGE +A  ++D  +  ++
Sbjct: 719 SLRFSRDGEILASGSMDNTVRLWD 742



 Score = 82.2 bits (194), Expect = 6e-15
 Identities = 58/197 (29%), Positives = 88/197 (44%), Gaps = 5/197 (2%)

Query: 234 SVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGK 293
           S SP  +++  +  + G + +W  Q+   ++  +GH+  +    +SP G + V+GG D  
Sbjct: 553 SFSPDRNYLLSSSED-GTVRLWSLQTFTCLVGYKGHNYPVWDTQFSPYGYYFVSGGHDRV 611

Query: 294 VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSP 353
            ++W T +      F  H A V+      N  +  + S D TVR +D+      R  T  
Sbjct: 612 ARLWATDHYQPLRIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGH 671

Query: 354 SLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTST 413
                  +    +G F A G  D   + +W I  G ++  L GH   V SL FS      
Sbjct: 672 K-GPIHSLTFSPNGRFLATGATD-GRVLLWDIGHGLMVGELKGHTDTVCSLRFS--RDGE 727

Query: 414 RLASASWDGTVRLWDCI 430
            LAS S D TVRLWD I
Sbjct: 728 ILASGSMDNTVRLWDAI 744



 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 44/175 (25%), Positives = 73/175 (41%), Gaps = 4/175 (2%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H   V G + S ++ + +SSS DGTVR + L  +         +   +        G + 
Sbjct: 545 HSGPVYGASFSPDRNYLLSSSEDGTVRLWSLQTFTCLVGYKGHNYPVWD-TQFSPYGYYF 603

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
            +GG D     +W+    + L +  GH A V+   F P   S  +A+ S D TVRLWD +
Sbjct: 604 VSGGHDRVAR-LWATDHYQPLRIFAGHLADVNCTRFHPN--SNYVATGSADRTVRLWDVL 660

Query: 431 DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
           +                + F P+G  +A    DG +  ++       G ++G +D
Sbjct: 661 NGNCVRIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGHGLMVGELKGHTD 715



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 26/116 (22%), Positives = 57/116 (49%), Gaps = 1/116 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +   ++H  +  + TG +     L ++ + N +   +  +  I S++ SP G ++A    
Sbjct: 633 VNCTRFHPNSNYVATGSADRTVRLWDVLNGNCVRIFTGHKGPIHSLTFSPNGRFLATGAT 692

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
           + G++L+W+      V + +GH+  +  L +S DG  + +G  D  V++W+    F
Sbjct: 693 D-GRVLLWDIGHGLMVGELKGHTDTVCSLRFSRDGEILASGSMDNTVRLWDAIKAF 747



 Score = 40.7 bits (91), Expect = 0.018
 Identities = 37/124 (29%), Positives = 53/124 (42%), Gaps = 15/124 (12%)

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           CF TF      ++ V  + +         D TVR + +T  +  R++   S    S +  
Sbjct: 465 CFYTFLNAYQGLTAVDVTDDSSLIAGGFADSTVRVWSVTP-KKLRSVKQAS--DLSLIDK 521

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
           +S          DV E  +   K    L++L GH  PV   +FSP      L S+S DGT
Sbjct: 522 ESD---------DVLER-IMDEKTASELKILYGHSGPVYGASFSP--DRNYLLSSSEDGT 569

Query: 424 VRLW 427
           VRLW
Sbjct: 570 VRLW 573



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 25/89 (28%), Positives = 40/89 (44%), Gaps = 5/89 (5%)

Query: 8   TGEYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGH 67
           T  Y+P    R+F   L +V C  +   S  +A GS D T ++  V  L    +   +GH
Sbjct: 617 TDHYQPL---RIFAGHLADVNCTRFHPNSNYVATGSADRTVRLWDV--LNGNCVRIFTGH 671

Query: 68  TDKIIGVFFERKSLDLITVSRNGQLCLWE 96
              I  + F      L T + +G++ LW+
Sbjct: 672 KGPIHSLTFSPNGRFLATGATDGRVLLWD 700



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 27/102 (26%), Positives = 44/102 (43%), Gaps = 3/102 (2%)

Query: 18  RVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFE 77
           R+F      +  L +S   R LA G+ D    +  + +   + +  L GHTD +  + F 
Sbjct: 666 RIFTGHKGPIHSLTFSPNGRFLATGATDGRVLLWDIGH--GLMVGELKGHTDTVCSLRFS 723

Query: 78  RKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRL 119
           R    L + S +  + LW+A I A E     D T+    + L
Sbjct: 724 RDGEILASGSMDNTVRLWDA-IKAFEDLETDDFTTATGHINL 764


>BC036377-1|AAH36377.1|  415|Homo sapiens WD repeat domain 69
           protein.
          Length = 415

 Score = 84.6 bits (200), Expect = 1e-15
 Identities = 66/299 (22%), Positives = 122/299 (40%), Gaps = 6/299 (2%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPP-GDWIAFAC 246
           LT V  +K     +TG       L +      ++TL    + + +I+ + P GD IA   
Sbjct: 95  LTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGS 154

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            +     +W  ++ +     +GH+ ++ CL+++P    V TG  D   K+W+  NG    
Sbjct: 155 FD-KTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVY 213

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSS 366
           T   H A +  ++ + +    ++ S D TV  +D    R    L      + S  + +  
Sbjct: 214 TLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIG-HCAEISSASFNWD 272

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
                 G  D     +W    GK +  L GH+  +    F    T   +A+AS DGT R+
Sbjct: 273 CSLILTGSMDK-TCKLWDATNGKCVATLTGHDDEILDSCFD--YTGKLIATASADGTARI 329

Query: 427 WDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
           +    R+   +      +  +++F P G  +   + D     ++  T +    +EG +D
Sbjct: 330 FSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTD 388



 Score = 76.6 bits (180), Expect = 3e-13
 Identities = 55/241 (22%), Positives = 104/241 (43%), Gaps = 5/241 (2%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++  + ++ ++ L+ TG       L ++ +   ++TL      I S+S +  GD I    
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGS 238

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            +   ++VW+  + + V    GH  +++  +++ D   ++TG  D   K+W+ TNG C  
Sbjct: 239 FD-HTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVA 297

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSS 366
           T   H   +         K   ++S DGT R +     +    L      + S ++ +  
Sbjct: 298 TLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE-GEISKISFNPQ 356

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
           G     G  D     +W  + G+ L+VL GH   + S AF+       + + S D T R+
Sbjct: 357 GNHLLTGSSDK-TARIWDAQTGQCLQVLEGHTDEIFSCAFN--YKGNIVITGSKDNTCRI 413

Query: 427 W 427
           W
Sbjct: 414 W 414



 Score = 62.9 bits (146), Expect = 4e-09
 Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 5/163 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC-SANKK 325
           + H L +T +A +  G   +TG +D   K+W+T +G    T   H+  V  +   +    
Sbjct: 89  KAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGD 148

Query: 326 FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSI 385
              + S D T + + +   + + T    +  +  C++ +      A G  D     +W I
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHT-AEIVCLSFNPQSTLVATGSMDT-TAKLWDI 206

Query: 386 KFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           + G+ +  L GH A + SL+F+   +  R+ + S+D TV +WD
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFN--TSGDRIITGSFDHTVVVWD 247



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 2/78 (2%)

Query: 20  FKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERK 79
           F+    E+ CL ++  S L+A GS DTT K+  ++  E +  Y+L GH+ +II + F   
Sbjct: 173 FRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV--YTLRGHSAEIISLSFNTS 230

Query: 80  SLDLITVSRNGQLCLWEA 97
              +IT S +  + +W+A
Sbjct: 231 GDRIITGSFDHTVVVWDA 248



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           E++ + ++     L  GS D T +I   +  + + +  L GHTD+I    F  K   +IT
Sbjct: 347 EISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQV--LEGHTDEIFSCAFNYKGNIVIT 404

Query: 86  VSRNGQLCLW 95
            S++    +W
Sbjct: 405 GSKDNTCRIW 414


>AK098821-1|BAC05425.1|  415|Homo sapiens protein ( Homo sapiens
           cDNA FLJ25955 fis, clone TST03904. ).
          Length = 415

 Score = 84.6 bits (200), Expect = 1e-15
 Identities = 66/299 (22%), Positives = 122/299 (40%), Gaps = 6/299 (2%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPP-GDWIAFAC 246
           LT V  +K     +TG       L +      ++TL    + + +I+ + P GD IA   
Sbjct: 95  LTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGDKIATGS 154

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            +     +W  ++ +     +GH+ ++ CL+++P    V TG  D   K+W+  NG    
Sbjct: 155 FD-KTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVY 213

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSS 366
           T   H A +  ++ + +    ++ S D TV  +D    R    L      + S  + +  
Sbjct: 214 TLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIG-HCAEISSASFNWD 272

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
                 G  D     +W    GK +  L GH+  +    F    T   +A+AS DGT R+
Sbjct: 273 CSLILTGSMDK-TCKLWDATNGKCVATLTGHDDEILDSCFD--YTGKLIATASADGTARI 329

Query: 427 WDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
           +    R+   +      +  +++F P G  +   + D     ++  T +    +EG +D
Sbjct: 330 FSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTD 388



 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 54/241 (22%), Positives = 103/241 (42%), Gaps = 5/241 (2%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++  + ++ ++ L+ TG       L ++ +   ++TL      I S+S +  GD I    
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGS 238

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            +   ++VW+  + + V    GH  +++  +++ D   ++TG  D   K+W+ TNG C  
Sbjct: 239 FD-HTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVA 297

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSS 366
           T   H   +         K   ++S DGT R +     +    L      + S ++ +  
Sbjct: 298 TLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE-GEISKISFNPQ 356

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
           G     G  D     +W  + G+ L+VL GH   + S AF+       + + S   T R+
Sbjct: 357 GNHLLTGSSDK-TARIWDAQTGQCLQVLEGHTDEIFSCAFN--YKGNIVITGSKGNTCRI 413

Query: 427 W 427
           W
Sbjct: 414 W 414



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 5/163 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC-SANKK 325
           + H L +T +A +  G   +TG +D   K+W++ +G    T   H+  V  +   +    
Sbjct: 89  KAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGD 148

Query: 326 FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSI 385
              + S D T + + +   + + T    +  +  C++ +      A G  D     +W I
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHT-AEIVCLSFNPQSTLVATGSMDT-TAKLWDI 206

Query: 386 KFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           + G+ +  L GH A + SL+F+   +  R+ + S+D TV +WD
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFN--TSGDRIITGSFDHTVVVWD 247



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 2/78 (2%)

Query: 20  FKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERK 79
           F+    E+ CL ++  S L+A GS DTT K+  ++  E +  Y+L GH+ +II + F   
Sbjct: 173 FRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV--YTLRGHSAEIISLSFNTS 230

Query: 80  SLDLITVSRNGQLCLWEA 97
              +IT S +  + +W+A
Sbjct: 231 GDRIITGSFDHTVVVWDA 248


>AK097409-1|BAC05039.1|  415|Homo sapiens protein ( Homo sapiens
           cDNA FLJ40090 fis, clone TESTI2003596, weakly similar to
           VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
          Length = 415

 Score = 84.6 bits (200), Expect = 1e-15
 Identities = 66/299 (22%), Positives = 122/299 (40%), Gaps = 6/299 (2%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPP-GDWIAFAC 246
           LT V  +K     +TG       L +      ++TL    + + +I+ + P GD IA   
Sbjct: 95  LTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGS 154

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            +     +W  ++ +     +GH+ ++ CL+++P    V TG  D   K+W+  NG    
Sbjct: 155 FD-KTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVY 213

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSS 366
           T   H A +  ++ + +    ++ S D TV  +D    R    L      + S  + +  
Sbjct: 214 TLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIG-HCAEISSASFNWD 272

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
                 G  D     +W    GK +  L GH+  +    F    T   +A+AS DGT R+
Sbjct: 273 CSLILTGSMDK-TCKLWDATNGKCVATLTGHDDEILDSCFD--YTGKLIATASADGTARI 329

Query: 427 WDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
           +    R+   +      +  +++F P G  +   + D     ++  T +    +EG +D
Sbjct: 330 FSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTD 388



 Score = 76.6 bits (180), Expect = 3e-13
 Identities = 55/241 (22%), Positives = 104/241 (43%), Gaps = 5/241 (2%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++  + ++ ++ L+ TG       L ++ +   ++TL      I S+S +  GD I    
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGS 238

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            +   ++VW+  + + V    GH  +++  +++ D   ++TG  D   K+W+ TNG C  
Sbjct: 239 FD-HTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVA 297

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSS 366
           T   H   +         K   ++S DGT R +     +    L      + S ++ +  
Sbjct: 298 TLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE-GEISKISFNPQ 356

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
           G     G  D     +W  + G+ L+VL GH   + S AF+       + + S D T R+
Sbjct: 357 GNHLLTGSSDK-TARIWDAQTGQCLQVLEGHTDEIFSCAFN--YKGNIVITGSKDNTCRI 413

Query: 427 W 427
           W
Sbjct: 414 W 414



 Score = 62.9 bits (146), Expect = 4e-09
 Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 5/163 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC-SANKK 325
           + H L +T +A +  G   +TG +D   K+W+T +G    T   H+  V  +   +    
Sbjct: 89  KAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGD 148

Query: 326 FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSI 385
              + S D T + + +   + + T    +  +  C++ +      A G  D     +W I
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHT-AEIVCLSFNPQSTLVATGSMDT-TAKLWDI 206

Query: 386 KFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           + G+ +  L GH A + SL+F+   +  R+ + S+D TV +WD
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFN--TSGDRIITGSFDHTVVVWD 247



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 2/78 (2%)

Query: 20  FKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERK 79
           F+    E+ CL ++  S L+A GS DTT K+  ++  E +  Y+L GH+ +II + F   
Sbjct: 173 FRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV--YTLRGHSAEIISLSFNTS 230

Query: 80  SLDLITVSRNGQLCLWEA 97
              +IT S +  + +W+A
Sbjct: 231 GDRIITGSFDHTVVVWDA 248



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           E++ + ++     L  GS D T +I   +  + + +  L GHTD+I    F  K   +IT
Sbjct: 347 EISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQV--LEGHTDEIFSCAFNYKGNIVIT 404

Query: 86  VSRNGQLCLW 95
            S++    +W
Sbjct: 405 GSKDNTCRIW 414


>AC073065-2|AAX93215.1|  415|Homo sapiens unknown protein.
          Length = 415

 Score = 84.6 bits (200), Expect = 1e-15
 Identities = 66/299 (22%), Positives = 122/299 (40%), Gaps = 6/299 (2%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPP-GDWIAFAC 246
           LT V  +K     +TG       L +      ++TL    + + +I+ + P GD IA   
Sbjct: 95  LTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGDKIATGS 154

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            +     +W  ++ +     +GH+ ++ CL+++P    V TG  D   K+W+  NG    
Sbjct: 155 FD-KTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVY 213

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSS 366
           T   H A +  ++ + +    ++ S D TV  +D    R    L      + S  + +  
Sbjct: 214 TLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIG-HCAEISSASFNWD 272

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
                 G  D     +W    GK +  L GH+  +    F    T   +A+AS DGT R+
Sbjct: 273 CSLILTGSMDK-TCKLWDATNGKCVATLTGHDDEILDSCFD--YTGKLIATASADGTARI 329

Query: 427 WDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
           +    R+   +      +  +++F P G  +   + D     ++  T +    +EG +D
Sbjct: 330 FSAATRKCIAKLEGHEGEISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQVLEGHTD 388



 Score = 76.6 bits (180), Expect = 3e-13
 Identities = 55/241 (22%), Positives = 104/241 (43%), Gaps = 5/241 (2%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++  + ++ ++ L+ TG       L ++ +   ++TL      I S+S +  GD I    
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGS 238

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            +   ++VW+  + + V    GH  +++  +++ D   ++TG  D   K+W+ TNG C  
Sbjct: 239 FD-HTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVA 297

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSS 366
           T   H   +         K   ++S DGT R +     +    L      + S ++ +  
Sbjct: 298 TLTGHDDEILDSCFDYTGKLIATASADGTARIFSAATRKCIAKLEGHE-GEISKISFNPQ 356

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
           G     G  D     +W  + G+ L+VL GH   + S AF+       + + S D T R+
Sbjct: 357 GNHLLTGSSDK-TARIWDAQTGQCLQVLEGHTDEIFSCAFN--YKGNIVITGSKDNTCRI 413

Query: 427 W 427
           W
Sbjct: 414 W 414



 Score = 62.9 bits (146), Expect = 4e-09
 Identities = 40/163 (24%), Positives = 75/163 (46%), Gaps = 5/163 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC-SANKK 325
           + H L +T +A +  G   +TG +D   K+W+T +G    T   H+  V  +   +    
Sbjct: 89  KAHILPLTNVALNKSGSCFITGSYDRTCKLWDTASGEELNTLEGHRNVVYAIAFNNPYGD 148

Query: 326 FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSI 385
              + S D T + + +   + + T    +  +  C++ +      A G  D     +W I
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHT-AEIVCLSFNPQSTLVATGSMDT-TAKLWDI 206

Query: 386 KFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           + G+ +  L GH A + SL+F+   +  R+ + S+D TV +WD
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFN--TSGDRIITGSFDHTVVVWD 247



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 2/78 (2%)

Query: 20  FKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERK 79
           F+    E+ CL ++  S L+A GS DTT K+  ++  E +  Y+L GH+ +II + F   
Sbjct: 173 FRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV--YTLRGHSAEIISLSFNTS 230

Query: 80  SLDLITVSRNGQLCLWEA 97
              +IT S +  + +W+A
Sbjct: 231 GDRIITGSFDHTVVVWDA 248



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 2/70 (2%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           E++ + ++     L  GS D T +I   +  + + +  L GHTD+I    F  K   +IT
Sbjct: 347 EISKISFNPQGNHLLTGSSDKTARIWDAQTGQCLQV--LEGHTDEIFSCAFNYKGNIVIT 404

Query: 86  VSRNGQLCLW 95
            S++    +W
Sbjct: 405 GSKDNTCRIW 414


>X04526-2|CAA28207.1|  340|Homo sapiens protein ( Human liver mRNA
           for beta-subunit signal transducing proteins Gs/Gi
           (beta-G). ).
          Length = 340

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 46/248 (18%), Positives = 104/248 (41%), Gaps = 8/248 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+   G 
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ + + + FVS + D + + +D+      +T T       + +  
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE-SDINAICF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG- 422
             +G   A G  D     ++ ++  + L +   H+  +  +       S RL  A +D  
Sbjct: 235 FPNGNAFATGSDDA-TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292

Query: 423 TVRLWDCI 430
              +WD +
Sbjct: 293 NCNVWDAL 300



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTL--TSPSLVQFSCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     +      SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRL-ASASWDGTVRLWDCIDREVQCEPIR 440
            W I+ G+      GH   V SL+ +P    TRL  S + D + +LWD   RE  C    
Sbjct: 169 -WDIETGQQTTTFTGHTGDVMSLSLAP---DTRLFVSGACDASAKLWDV--REGMCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+G   A  + D     F+
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFD 254


>M36430-1|AAA63265.1|  247|Homo sapiens protein ( Human transducin
           beta-1 subunit mRNA, 3' end. ).
          Length = 247

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 75  LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 134

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 135 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 194

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 195 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 247



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 54/227 (23%), Positives = 92/227 (40%), Gaps = 10/227 (4%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSG-VTCS--ANKKFFVS 329
           MTC AY+P G +V  GG D    ++N       V      A  +G ++C    +    V+
Sbjct: 8   MTC-AYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVT 66

Query: 330 SSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGK 389
           SS D T   +D+   +   T T  +    S ++L        +G  D     +W ++ G 
Sbjct: 67  SSGDTTCALWDIETGQQTTTFTGHTGDVMS-LSLAPDTRLFVSGACDA-SAKLWDVREGM 124

Query: 390 LLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC-IDREVQC-EPIRLNSDALQ 447
             +   GHE+ ++++ F P       A+ S D T RL+D   D+E+       +      
Sbjct: 125 CRQTFTGHESDINAICFFP--NGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITS 182

Query: 448 VAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSGRAETD 494
           V+F   G  +     D N   ++    ++ G + G  +  S    TD
Sbjct: 183 VSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCLGVTD 229



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 33/164 (20%), Positives = 66/164 (40%), Gaps = 5/164 (3%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH+  ++C  +  D   +VT   D    +W+   G    TF  H   V  ++ + + + F
Sbjct: 48  GHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 106

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS + D + + +D+      +T T       + +    +G   A G  D     ++ ++ 
Sbjct: 107 VSGACDASAKLWDVREGMCRQTFTGHE-SDINAICFFPNGNAFATGSDDA-TCRLFDLRA 164

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG-TVRLWDCI 430
            + L +   H+  +  +       S RL  A +D     +WD +
Sbjct: 165 DQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 207


>CR456784-1|CAG33065.1|  340|Homo sapiens GNB1 protein.
          Length = 340

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 46/248 (18%), Positives = 104/248 (41%), Gaps = 8/248 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+   G 
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ + + + FVS + D + + +D+      +T T       + +  
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE-SDINAICF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG- 422
             +G   A G  D     ++ ++  + L +   H+  +  +       S RL  A +D  
Sbjct: 235 FPNGNAFATGSDDA-TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292

Query: 423 TVRLWDCI 430
              +WD +
Sbjct: 293 NCNVWDAL 300



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTL--TSPSLVQFSCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     +      SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRL-ASASWDGTVRLWDCIDREVQCEPIR 440
            W I+ G+      GH   V SL+ +P    TRL  S + D + +LWD   RE  C    
Sbjct: 169 -WDIETGQQTTTFTGHTGDVMSLSLAP---DTRLFVSGACDASAKLWDV--REGMCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+G   A  + D     F+
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFD 254


>BT007305-1|AAP35969.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 1 protein.
          Length = 340

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 46/248 (18%), Positives = 104/248 (41%), Gaps = 8/248 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+   G 
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ + + + FVS + D + + +D+      +T T       + +  
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE-SDINAICF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG- 422
             +G   A G  D     ++ ++  + L +   H+  +  +       S RL  A +D  
Sbjct: 235 FPNGNAFATGSDDA-TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292

Query: 423 TVRLWDCI 430
              +WD +
Sbjct: 293 NCNVWDAL 300



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTL--TSPSLVQFSCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     +      SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRL-ASASWDGTVRLWDCIDREVQCEPIR 440
            W I+ G+      GH   V SL+ +P    TRL  S + D + +LWD   RE  C    
Sbjct: 169 -WDIETGQQTTTFTGHTGDVMSLSLAP---DTRLFVSGACDASAKLWDV--REGMCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+G   A  + D     F+
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFD 254


>BC008991-1|AAH08991.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 1 protein.
          Length = 340

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 46/248 (18%), Positives = 104/248 (41%), Gaps = 8/248 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+   G 
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ + + + FVS + D + + +D+      +T T       + +  
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE-SDINAICF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG- 422
             +G   A G  D     ++ ++  + L +   H+  +  +       S RL  A +D  
Sbjct: 235 FPNGNAFATGSDDA-TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292

Query: 423 TVRLWDCI 430
              +WD +
Sbjct: 293 NCNVWDAL 300



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTL--TSPSLVQFSCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     +      SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRL-ASASWDGTVRLWDCIDREVQCEPIR 440
            W I+ G+      GH   V SL+ +P    TRL  S + D + +LWD   RE  C    
Sbjct: 169 -WDIETGQQTTTFTGHTGDVMSLSLAP---DTRLFVSGACDASAKLWDV--REGMCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+G   A  + D     F+
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFD 254


>BC005888-1|AAH05888.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 1 protein.
          Length = 340

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 46/248 (18%), Positives = 104/248 (41%), Gaps = 8/248 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+   G 
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ + + + FVS + D + + +D+      +T T       + +  
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE-SDINAICF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG- 422
             +G   A G  D     ++ ++  + L +   H+  +  +       S RL  A +D  
Sbjct: 235 FPNGNAFATGSDDA-TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292

Query: 423 TVRLWDCI 430
              +WD +
Sbjct: 293 NCNVWDAL 300



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTL--TSPSLVQFSCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     +      SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRL-ASASWDGTVRLWDCIDREVQCEPIR 440
            W I+ G+      GH   V SL+ +P    TRL  S + D + +LWD   RE  C    
Sbjct: 169 -WDIETGQQTTTFTGHTGDVMSLSLAP---DTRLFVSGACDASAKLWDV--REGMCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+G   A  + D     F+
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFD 254


>BC004186-1|AAH04186.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 1 protein.
          Length = 340

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 46/248 (18%), Positives = 104/248 (41%), Gaps = 8/248 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+   G 
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ + + + FVS + D + + +D+      +T T       + +  
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE-SDINAICF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG- 422
             +G   A G  D     ++ ++  + L +   H+  +  +       S RL  A +D  
Sbjct: 235 FPNGNAFATGSDDA-TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292

Query: 423 TVRLWDCI 430
              +WD +
Sbjct: 293 NCNVWDAL 300



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTL--TSPSLVQFSCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     +      SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRL-ASASWDGTVRLWDCIDREVQCEPIR 440
            W I+ G+      GH   V SL+ +P    TRL  S + D + +LWD   RE  C    
Sbjct: 169 -WDIETGQQTTTFTGHTGDVMSLSLAP---DTRLFVSGACDASAKLWDV--REGMCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+G   A  + D     F+
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFD 254


>AL109917-5|CAI95654.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 1 protein.
          Length = 340

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 46/248 (18%), Positives = 104/248 (41%), Gaps = 8/248 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+   G 
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ + + + FVS + D + + +D+      +T T       + +  
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE-SDINAICF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG- 422
             +G   A G  D     ++ ++  + L +   H+  +  +       S RL  A +D  
Sbjct: 235 FPNGNAFATGSDDA-TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292

Query: 423 TVRLWDCI 430
              +WD +
Sbjct: 293 NCNVWDAL 300



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTL--TSPSLVQFSCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     +      SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRL-ASASWDGTVRLWDCIDREVQCEPIR 440
            W I+ G+      GH   V SL+ +P    TRL  S + D + +LWD   RE  C    
Sbjct: 169 -WDIETGQQTTTFTGHTGDVMSLSLAP---DTRLFVSGACDASAKLWDV--REGMCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+G   A  + D     F+
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFD 254


>AL031282-15|CAI20051.1|  197|Homo sapiens guanine nucleotide
           binding protein (G protein), beta polypeptide 1 protein.
          Length = 197

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 25  LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 84

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 85  DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 144

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 145 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 197



 Score = 35.9 bits (79), Expect = 0.52
 Identities = 31/159 (19%), Positives = 63/159 (39%), Gaps = 5/159 (3%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSL 332
           ++C  +  D   +VT   D    +W+   G    TF  H   V  ++ + + + FVS + 
Sbjct: 3   LSCCRFLDDN-QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGAC 61

Query: 333 DGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLE 392
           D + + +D+      +T T       + +    +G   A G  D     ++ ++  + L 
Sbjct: 62  DASAKLWDVREGMCRQTFTGHE-SDINAICFFPNGNAFATGSDDA-TCRLFDLRADQEL- 118

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDG-TVRLWDCI 430
           +   H+  +  +       S RL  A +D     +WD +
Sbjct: 119 MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 157


>AL031282-2|CAI20029.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 1 protein.
          Length = 340

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 46/248 (18%), Positives = 104/248 (41%), Gaps = 8/248 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+   G 
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ + + + FVS + D + + +D+      +T T       + +  
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE-SDINAICF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG- 422
             +G   A G  D     ++ ++  + L +   H+  +  +       S RL  A +D  
Sbjct: 235 FPNGNAFATGSDDA-TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292

Query: 423 TVRLWDCI 430
              +WD +
Sbjct: 293 NCNVWDAL 300



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTL--TSPSLVQFSCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     +      SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRL-ASASWDGTVRLWDCIDREVQCEPIR 440
            W I+ G+      GH   V SL+ +P    TRL  S + D + +LWD   RE  C    
Sbjct: 169 -WDIETGQQTTTFTGHTGDVMSLSLAP---DTRLFVSGACDASAKLWDV--REGMCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+G   A  + D     F+
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFD 254


>AF501882-1|AAM15918.1|  340|Homo sapiens guanine nucleotide binding
           protein beta 1 protein.
          Length = 340

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 46/248 (18%), Positives = 104/248 (41%), Gaps = 8/248 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+   G 
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ + + + FVS + D + + +D+      +T T       + +  
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE-SDINAICF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG- 422
             +G   A G  D     ++ ++  + L +   H+  +  +       S RL  A +D  
Sbjct: 235 FPNGNAFATGSDDA-TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292

Query: 423 TVRLWDCI 430
              +WD +
Sbjct: 293 NCNVWDAL 300



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTL--TSPSLVQFSCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     +      SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRL-ASASWDGTVRLWDCIDREVQCEPIR 440
            W I+ G+      GH   V SL+ +P    TRL  S + D + +LWD   RE  C    
Sbjct: 169 -WDIETGQQTTTFTGHTGDVMSLSLAP---DTRLFVSGACDASAKLWDV--REGMCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+G   A  + D     F+
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFD 254


>AF070603-1|AAC28655.1|  207|Homo sapiens beta-subunit signal
           transducing proteins GS/GI protein.
          Length = 207

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 49/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 35  LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 94

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 95  DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 154

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW         VL GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 155 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCLGV--TDDGMAVATGSWDSFLKIWN 207



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 33/164 (20%), Positives = 66/164 (40%), Gaps = 5/164 (3%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH+  ++C  +  D   +VT   D    +W+   G    TF  H   V  ++ + + + F
Sbjct: 8   GHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAPDTRLF 66

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           VS + D + + +D+      +T T       + +    +G   A G  D     ++ ++ 
Sbjct: 67  VSGACDASAKLWDVREGMCRQTFTGHE-SDINAICFFPNGNAFATGSDDA-TCRLFDLRA 124

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG-TVRLWDCI 430
            + L +   H+  +  +       S RL  A +D     +WD +
Sbjct: 125 DQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDAL 167


>AF052432-1|AAC09328.1|  655|Homo sapiens katanin p80 subunit
           protein.
          Length = 655

 Score = 82.2 bits (194), Expect = 6e-15
 Identities = 58/201 (28%), Positives = 89/201 (44%), Gaps = 4/201 (1%)

Query: 282 GLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
           G  + TGG D +V +W+     C ++   H + V  V  +  ++  V+ S  G++R +DL
Sbjct: 33  GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92

Query: 342 TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPV 401
              +  RTL          +     GEF A+G QD   I +W I+    +    GH   V
Sbjct: 93  EAAKILRTLMGLK-ANICSLDFHPYGEFVASGSQDT-NIKLWDIRRKGCVFRYRGHSQAV 150

Query: 402 SSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVST 461
             L FSP      LASA+ D TV+LWD    ++  E          V F P+   +A  +
Sbjct: 151 RCLRFSP--DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGS 208

Query: 462 LDGNITFFEPSTCEQTGSVEG 482
            DG I F++    +    +EG
Sbjct: 209 SDGTIRFWDLEKFQVVSRIEG 229



 Score = 82.2 bits (194), Expect = 6e-15
 Identities = 52/195 (26%), Positives = 93/195 (47%), Gaps = 4/195 (2%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           +V+ +   +L+V G  SG   + ++    ++ TL   +  I S+   P G+++A    + 
Sbjct: 68  SVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEFVASGSQDT 127

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + +W+ + +  V + +GHS  + CL +SPDG  + +   D  VK+W+ T G     F 
Sbjct: 128 N-IKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP 186

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNF-RTLTSPSLVQFSCVALDSSGE 368
            H   V+ V    N+    S S DGT+R +DL +++   R    P  V+   V  +  G 
Sbjct: 187 GHTGPVNVVEFHPNEYLLASGSSDGTIRFWDLEKFQVVSRIEGEPGPVR--SVLFNPDGC 244

Query: 369 FCAAGGQDVFEIFVW 383
              +G QD   ++ W
Sbjct: 245 CLYSGCQDSLRVYGW 259



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 54/223 (24%), Positives = 88/223 (39%), Gaps = 7/223 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W       +M   GH+  +  +  +     +V G   G ++VW+        T    KA
Sbjct: 47  LWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGLKA 106

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYR-NFRTLTSPSLVQFSCVALDSSGEFCAA 372
            +  +      +F  S S D  ++ +D+ R    FR       V+  C+     G++ A+
Sbjct: 107 NICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVR--CLRFSPDGKWLAS 164

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
              D   + +W +  GK++    GH  PV+ + F P      LAS S DGT+R WD    
Sbjct: 165 AADD-HTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP--NEYLLASGSSDGTIRFWDLEKF 221

Query: 433 EVQCEPIRLNSDALQVAFRPDGEEIAVSTLDG-NITFFEPSTC 474
           +V             V F PDG  +     D   +  +EP  C
Sbjct: 222 QVVSRIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERC 264



 Score = 49.6 bits (113), Expect = 4e-05
 Identities = 31/112 (27%), Positives = 53/112 (47%), Gaps = 3/112 (2%)

Query: 359 SCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASA 418
           S V   +SG   A GG D   + +WSI     +  L GH +PV S+  +       + + 
Sbjct: 25  SLVLGKASGRLLATGGDDC-RVNLWSINKPNCIMSLTGHTSPVESVRLN--TPEELIVAG 81

Query: 419 SWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           S  G++R+WD    ++    + L ++   + F P GE +A  + D NI  ++
Sbjct: 82  SQSGSIRVWDLEAAKILRTLMGLKANICSLDFHPYGEFVASGSQDTNIKLWD 133


>BC018698-1|AAH18698.1|  504|Homo sapiens PRP19/PSO4 pre-mRNA
           processing factor 19 homolog (S. cerevisiae) protein.
          Length = 504

 Score = 81.8 bits (193), Expect = 8e-15
 Identities = 45/199 (22%), Positives = 96/199 (48%), Gaps = 6/199 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+T+V +H    L+ +        +  +P+ + +  +   E  ++ +S+   GD++  + 
Sbjct: 266 KVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSS 325

Query: 247 PNIGQLLVW-EWQSEQYVMK--QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
            +  Q   + + Q+ + + K   +     +TC  + PDGL   TG  D ++K+W+     
Sbjct: 326 DD--QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERT 383

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
               F  H   ++ +  S N  +  +++ D +V+ +DL + +NF+TL   +  +   +  
Sbjct: 384 NVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIF 443

Query: 364 DSSGEFCAAGGQDVFEIFV 382
           D SG + A GG DV +I++
Sbjct: 444 DQSGTYLALGGTDV-QIYI 461



 Score = 75.4 bits (177), Expect = 7e-13
 Identities = 47/178 (26%), Positives = 83/178 (46%), Gaps = 4/178 (2%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           ++V++  SEQ +   +GH+  +T + + P    V +   D  +++W+  N  C      H
Sbjct: 246 VVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAH 305

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLT-SPSLVQFSCVALDSSGEFC 370
           ++ V+G++  A   + +SSS D      D+   R    +T   S    +C      G   
Sbjct: 306 ESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIF 365

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             G  D  +I +W +K    +    GH  P++S+AFS       LA+A+ D +V+LWD
Sbjct: 366 GTGTMD-SQIKIWDLKERTNVANFPGHSGPITSIAFSE--NGYYLATAADDSSVKLWD 420



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 32/155 (20%), Positives = 69/155 (44%), Gaps = 4/155 (2%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           LT  Q+H +  +  TG       + ++ +   +         I+SI+ S  G ++A A  
Sbjct: 353 LTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 412

Query: 248 NIGQLLVWEWQS-EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
           +   + +W+ +  + +   Q  ++ ++  L +   G ++  GG D  V+++        +
Sbjct: 413 D-SSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIYICKQWTEIL 469

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
            F EH    +GV    + KF  S+ +D +++ Y L
Sbjct: 470 HFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL 504


>BC018665-1|AAH18665.1|  504|Homo sapiens PRP19/PSO4 pre-mRNA
           processing factor 19 homolog (S. cerevisiae) protein.
          Length = 504

 Score = 81.8 bits (193), Expect = 8e-15
 Identities = 45/199 (22%), Positives = 96/199 (48%), Gaps = 6/199 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+T+V +H    L+ +        +  +P+ + +  +   E  ++ +S+   GD++  + 
Sbjct: 266 KVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSS 325

Query: 247 PNIGQLLVW-EWQSEQYVMK--QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
            +  Q   + + Q+ + + K   +     +TC  + PDGL   TG  D ++K+W+     
Sbjct: 326 DD--QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERT 383

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
               F  H   ++ +  S N  +  +++ D +V+ +DL + +NF+TL   +  +   +  
Sbjct: 384 NVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIF 443

Query: 364 DSSGEFCAAGGQDVFEIFV 382
           D SG + A GG DV +I++
Sbjct: 444 DQSGTYLALGGTDV-QIYI 461



 Score = 75.4 bits (177), Expect = 7e-13
 Identities = 47/178 (26%), Positives = 83/178 (46%), Gaps = 4/178 (2%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           ++V++  SEQ +   +GH+  +T + + P    V +   D  +++W+  N  C      H
Sbjct: 246 VVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAH 305

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLT-SPSLVQFSCVALDSSGEFC 370
           ++ V+G++  A   + +SSS D      D+   R    +T   S    +C      G   
Sbjct: 306 ESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIF 365

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             G  D  +I +W +K    +    GH  P++S+AFS       LA+A+ D +V+LWD
Sbjct: 366 GTGTMD-SQIKIWDLKERTNVANFPGHSGPITSIAFSE--NGYYLATAADDSSVKLWD 420



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 32/155 (20%), Positives = 69/155 (44%), Gaps = 4/155 (2%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           LT  Q+H +  +  TG       + ++ +   +         I+SI+ S  G ++A A  
Sbjct: 353 LTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 412

Query: 248 NIGQLLVWEWQS-EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
           +   + +W+ +  + +   Q  ++ ++  L +   G ++  GG D  V+++        +
Sbjct: 413 D-SSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIYICKQWTEIL 469

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
            F EH    +GV    + KF  S+ +D +++ Y L
Sbjct: 470 HFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL 504


>BC008719-1|AAH08719.1|  504|Homo sapiens PRP19/PSO4 pre-mRNA
           processing factor 19 homolog (S. cerevisiae) protein.
          Length = 504

 Score = 81.8 bits (193), Expect = 8e-15
 Identities = 45/199 (22%), Positives = 96/199 (48%), Gaps = 6/199 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+T+V +H    L+ +        +  +P+ + +  +   E  ++ +S+   GD++  + 
Sbjct: 266 KVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSS 325

Query: 247 PNIGQLLVW-EWQSEQYVMK--QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
            +  Q   + + Q+ + + K   +     +TC  + PDGL   TG  D ++K+W+     
Sbjct: 326 DD--QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERT 383

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
               F  H   ++ +  S N  +  +++ D +V+ +DL + +NF+TL   +  +   +  
Sbjct: 384 NVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIF 443

Query: 364 DSSGEFCAAGGQDVFEIFV 382
           D SG + A GG DV +I++
Sbjct: 444 DQSGTYLALGGTDV-QIYI 461



 Score = 75.4 bits (177), Expect = 7e-13
 Identities = 47/178 (26%), Positives = 83/178 (46%), Gaps = 4/178 (2%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           ++V++  SEQ +   +GH+  +T + + P    V +   D  +++W+  N  C      H
Sbjct: 246 VVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAH 305

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLT-SPSLVQFSCVALDSSGEFC 370
           ++ V+G++  A   + +SSS D      D+   R    +T   S    +C      G   
Sbjct: 306 ESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIF 365

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             G  D  +I +W +K    +    GH  P++S+AFS       LA+A+ D +V+LWD
Sbjct: 366 GTGTMD-SQIKIWDLKERTNVANFPGHSGPITSIAFSE--NGYYLATAADDSSVKLWD 420



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 32/155 (20%), Positives = 69/155 (44%), Gaps = 4/155 (2%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           LT  Q+H +  +  TG       + ++ +   +         I+SI+ S  G ++A A  
Sbjct: 353 LTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 412

Query: 248 NIGQLLVWEWQS-EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
           +   + +W+ +  + +   Q  ++ ++  L +   G ++  GG D  V+++        +
Sbjct: 413 D-SSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIYICKQWTEIL 469

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
            F EH    +GV    + KF  S+ +D +++ Y L
Sbjct: 470 HFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL 504


>AJ131186-1|CAB51857.1|  504|Homo sapiens nuclear matrix protein
           NMP200 protein.
          Length = 504

 Score = 81.8 bits (193), Expect = 8e-15
 Identities = 45/199 (22%), Positives = 96/199 (48%), Gaps = 6/199 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+T+V +H    L+ +        +  +P+ + +  +   E  ++ +S+   GD++  + 
Sbjct: 266 KVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSS 325

Query: 247 PNIGQLLVW-EWQSEQYVMK--QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
            +  Q   + + Q+ + + K   +     +TC  + PDGL   TG  D ++K+W+     
Sbjct: 326 DD--QYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERT 383

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
               F  H   ++ +  S N  +  +++ D +V+ +DL + +NF+TL   +  +   +  
Sbjct: 384 NVANFPGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVKSLIF 443

Query: 364 DSSGEFCAAGGQDVFEIFV 382
           D SG + A GG DV +I++
Sbjct: 444 DQSGTYLALGGTDV-QIYI 461



 Score = 75.4 bits (177), Expect = 7e-13
 Identities = 47/178 (26%), Positives = 83/178 (46%), Gaps = 4/178 (2%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           ++V++  SEQ +   +GH+  +T + + P    V +   D  +++W+  N  C      H
Sbjct: 246 VVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVPNASCVQVVRAH 305

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLT-SPSLVQFSCVALDSSGEFC 370
           ++ V+G++  A   + +SSS D      D+   R    +T   S    +C      G   
Sbjct: 306 ESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIF 365

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             G  D  +I +W +K    +    GH  P++S+AFS       LA+A+ D +V+LWD
Sbjct: 366 GTGTMD-SQIKIWDLKERTNVANFPGHSGPITSIAFSE--NGYYLATAADDSSVKLWD 420



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 32/155 (20%), Positives = 69/155 (44%), Gaps = 4/155 (2%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           LT  Q+H +  +  TG       + ++ +   +         I+SI+ S  G ++A A  
Sbjct: 353 LTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANFPGHSGPITSIAFSENGYYLATAAD 412

Query: 248 NIGQLLVWEWQS-EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
           +   + +W+ +  + +   Q  ++ ++  L +   G ++  GG D  V+++        +
Sbjct: 413 D-SSVKLWDLRKLKNFKTLQLDNNFEVKSLIFDQSGTYLALGGTD--VQIYICKQWTEIL 469

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
            F EH    +GV    + KF  S+ +D +++ Y L
Sbjct: 470 HFTEHSGLTTGVAFGHHAKFIASTGMDRSLKFYSL 504


>AL121990-7|CAI22015.1|  589|Homo sapiens TAF5-like RNA polymerase
           II, p300/CBP-associated factor (PCAF)-associated facto
           protein.
          Length = 589

 Score = 81.0 bits (191), Expect = 1e-14
 Identities = 52/184 (28%), Positives = 85/184 (46%), Gaps = 4/184 (2%)

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C     +  W+  S    +  QGH+  +  L  SP  L+  +G  D   ++W+    + 
Sbjct: 359 SCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYP 418

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
              +  H A V  V    N  +  + S D TVR +   +  + R  T       S +A  
Sbjct: 419 LRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLS-LAFS 477

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G++ A+ G+D   + +W +  G L + L GH   ++SL FSP   S  +ASAS D +V
Sbjct: 478 PNGKYLASAGEDQ-RLKLWDLASGTLYKELRGHTDNITSLTFSP--DSGLIASASMDNSV 534

Query: 425 RLWD 428
           R+WD
Sbjct: 535 RVWD 538



 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 6/219 (2%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +    +  D   +++   D  ++ W+  +    V +  H   V  +  S    +
Sbjct: 339 RGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLY 398

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIK 386
           F S S D T R +   R    R + +  L    CV    +  + A G  D   + +WS +
Sbjct: 399 FASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTDK-TVRLWSAQ 456

Query: 387 FGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL 446
            G  + +  GH  PV SLAFSP      LASA  D  ++LWD     +  E +R ++D +
Sbjct: 457 QGNSVRLFTGHRGPVLSLAFSPN--GKYLASAGEDQRLKLWDLASGTLYKE-LRGHTDNI 513

Query: 447 -QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRS 484
             + F PD   IA +++D ++  ++      +   +G S
Sbjct: 514 TSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSS 552



 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 24/88 (27%), Positives = 46/88 (52%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W  Q    V    GH   +  LA+SP+G ++ + G D ++K+W+  +G  +     H  
Sbjct: 452 LWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTD 511

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDL 341
            ++ +T S +     S+S+D +VR +D+
Sbjct: 512 NITSLTFSPDSGLIASASMDNSVRVWDI 539



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 29/114 (25%), Positives = 55/114 (48%), Gaps = 1/114 (0%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           V++H  +  L TG +     L      N +   +     + S++ SP G ++A A  +  
Sbjct: 432 VKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGED-Q 490

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +L +W+  S     + +GH+ ++T L +SPD   + +   D  V+VW+  N +C
Sbjct: 491 RLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYC 544



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 18/79 (22%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 18  RVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFE 77
           R++   L +V C+ +   S  LA GS D T ++ + +   ++ ++  +GH   ++ + F 
Sbjct: 420 RIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLF--TGHRGPVLSLAFS 477

Query: 78  RKSLDLITVSRNGQLCLWE 96
                L +   + +L LW+
Sbjct: 478 PNGKYLASAGEDQRLKLWD 496


>AJ009770-1|CAA08816.1|  260|Homo sapiens putative transcription
           factor protein.
          Length = 260

 Score = 81.0 bits (191), Expect = 1e-14
 Identities = 52/184 (28%), Positives = 85/184 (46%), Gaps = 4/184 (2%)

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C     +  W+  S    +  QGH+  +  L  SP  L+  +G  D   ++W+    + 
Sbjct: 30  SCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYP 89

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
              +  H A V  V    N  +  + S D TVR +   +  + R  T       S +A  
Sbjct: 90  LRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLS-LAFS 148

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G++ A+ G+D   + +W +  G L + L GH   ++SL FSP   S  +ASAS D +V
Sbjct: 149 PNGKYLASAGEDQ-RLKLWDLASGTLYKELRGHTDNITSLTFSP--DSGLIASASMDNSV 205

Query: 425 RLWD 428
           R+WD
Sbjct: 206 RVWD 209



 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 6/219 (2%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +    +  D   +++   D  ++ W+  +    V +  H   V  +  S    +
Sbjct: 10  RGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLY 69

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIK 386
           F S S D T R +   R    R + +  L    CV    +  + A G  D   + +WS +
Sbjct: 70  FASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTDK-TVRLWSAQ 127

Query: 387 FGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL 446
            G  + +  GH  PV SLAFSP      LASA  D  ++LWD     +  E +R ++D +
Sbjct: 128 QGNSVRLFTGHRGPVLSLAFSPN--GKYLASAGEDQRLKLWDLASGTLYKE-LRGHTDNI 184

Query: 447 -QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRS 484
             + F PD   IA +++D ++  ++      +   +G S
Sbjct: 185 TSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSS 223



 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 24/88 (27%), Positives = 46/88 (52%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W  Q    V    GH   +  LA+SP+G ++ + G D ++K+W+  +G  +     H  
Sbjct: 123 LWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTD 182

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDL 341
            ++ +T S +     S+S+D +VR +D+
Sbjct: 183 NITSLTFSPDSGLIASASMDNSVRVWDI 210



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 29/114 (25%), Positives = 55/114 (48%), Gaps = 1/114 (0%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           V++H  +  L TG +     L      N +   +     + S++ SP G ++A A  +  
Sbjct: 103 VKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGED-Q 161

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +L +W+  S     + +GH+ ++T L +SPD   + +   D  V+VW+  N +C
Sbjct: 162 RLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYC 215



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 18/79 (22%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 18  RVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFE 77
           R++   L +V C+ +   S  LA GS D T ++ + +   ++ ++  +GH   ++ + F 
Sbjct: 91  RIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLF--TGHRGPVLSLAFS 148

Query: 78  RKSLDLITVSRNGQLCLWE 96
                L +   + +L LW+
Sbjct: 149 PNGKYLASAGEDQRLKLWD 167


>AF069736-1|AAC39906.1|  589|Homo sapiens PCAF associated factor 65
           beta protein.
          Length = 589

 Score = 81.0 bits (191), Expect = 1e-14
 Identities = 52/184 (28%), Positives = 85/184 (46%), Gaps = 4/184 (2%)

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C     +  W+  S    +  QGH+  +  L  SP  L+  +G  D   ++W+    + 
Sbjct: 359 SCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLYFASGSHDRTARLWSFDRTYP 418

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
              +  H A V  V    N  +  + S D TVR +   +  + R  T       S +A  
Sbjct: 419 LRIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLS-LAFS 477

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G++ A+ G+D   + +W +  G L + L GH   ++SL FSP   S  +ASAS D +V
Sbjct: 478 PNGKYLASAGEDQ-RLKLWDLASGTLYKELRGHTDNITSLTFSP--DSGLIASASMDNSV 534

Query: 425 RLWD 428
           R+WD
Sbjct: 535 RVWD 538



 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 55/219 (25%), Positives = 95/219 (43%), Gaps = 6/219 (2%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +    +  D   +++   D  ++ W+  +    V +  H   V  +  S    +
Sbjct: 339 RGHCGPVYSTRFLADSSGLLSCSEDMSIRYWDLGSFTNTVLYQGHAYPVWDLDISPYSLY 398

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIK 386
           F S S D T R +   R    R + +  L    CV    +  + A G  D   + +WS +
Sbjct: 399 FASGSHDRTARLWSFDRTYPLR-IYAGHLADVDCVKFHPNSNYLATGSTDK-TVRLWSAQ 456

Query: 387 FGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL 446
            G  + +  GH  PV SLAFSP      LASA  D  ++LWD     +  E +R ++D +
Sbjct: 457 QGNSVRLFTGHRGPVLSLAFSPN--GKYLASAGEDQRLKLWDLASGTLYKE-LRGHTDNI 513

Query: 447 -QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRS 484
             + F PD   IA +++D ++  ++      +   +G S
Sbjct: 514 TSLTFSPDSGLIASASMDNSVRVWDIRNTYCSAPADGSS 552



 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 24/88 (27%), Positives = 46/88 (52%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W  Q    V    GH   +  LA+SP+G ++ + G D ++K+W+  +G  +     H  
Sbjct: 452 LWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGEDQRLKLWDLASGTLYKELRGHTD 511

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDL 341
            ++ +T S +     S+S+D +VR +D+
Sbjct: 512 NITSLTFSPDSGLIASASMDNSVRVWDI 539



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 29/114 (25%), Positives = 55/114 (48%), Gaps = 1/114 (0%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           V++H  +  L TG +     L      N +   +     + S++ SP G ++A A  +  
Sbjct: 432 VKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLFTGHRGPVLSLAFSPNGKYLASAGED-Q 490

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +L +W+  S     + +GH+ ++T L +SPD   + +   D  V+VW+  N +C
Sbjct: 491 RLKLWDLASGTLYKELRGHTDNITSLTFSPDSGLIASASMDNSVRVWDIRNTYC 544



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 18/79 (22%), Positives = 39/79 (49%), Gaps = 2/79 (2%)

Query: 18  RVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFE 77
           R++   L +V C+ +   S  LA GS D T ++ + +   ++ ++  +GH   ++ + F 
Sbjct: 420 RIYAGHLADVDCVKFHPNSNYLATGSTDKTVRLWSAQQGNSVRLF--TGHRGPVLSLAFS 477

Query: 78  RKSLDLITVSRNGQLCLWE 96
                L +   + +L LW+
Sbjct: 478 PNGKYLASAGEDQRLKLWD 496


>U82756-1|AAC02261.1|  520|Homo sapiens WD splicing factor Hprp4p
           protein.
          Length = 520

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTG 288
           R++ +   P G ++   C +    L W+ ++++ ++ Q+GHS+ +  +A+  DG    TG
Sbjct: 323 RVARVMWHPSGRFLGTTCYDRSWRL-WDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTG 381

Query: 289 GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFR 348
           G D   +VW+   G C +    H   + G+  S N     + S D T + +DL + R   
Sbjct: 382 GLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 441

Query: 349 TLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
           T+ +   +          G F   G  D     +W+      L+ L GHE  V  L  S 
Sbjct: 442 TIPAHQNLVTGVKFEPIHGNFLLTGAYD-NTAKIWTHPGWSPLKTLAGHEGKVMGLDISS 500

Query: 409 TLTSTRLASASWDGTVRLW 427
                 +A+ S+D T +LW
Sbjct: 501 --DGQLIATCSYDRTFKLW 517



 Score = 65.7 bits (153), Expect = 6e-10
 Identities = 41/168 (24%), Positives = 73/168 (43%), Gaps = 4/168 (2%)

Query: 265 KQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK 324
           K+Q HS+  + ++  P  +++ +   DG VK+W+  +         H   V+ V    + 
Sbjct: 274 KEQLHSIPKSTVSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSG 333

Query: 325 KFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWS 384
           +F  ++  D + R +DL            S+  +  +A    G     GG D F   VW 
Sbjct: 334 RFLGTTCYDRSWRLWDLEAQEEILHQEGHSMGVYD-IAFHQDGSLAGTGGLDAFG-RVWD 391

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
           ++ G+ +  L GH   +  + FSP      +A+ S D T ++WD   R
Sbjct: 392 LRTGRCIMFLEGHLKEIYGINFSP--NGYHIATGSGDNTCKVWDLRQR 437



 Score = 65.3 bits (152), Expect = 7e-10
 Identities = 55/242 (22%), Positives = 102/242 (42%), Gaps = 10/242 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTL---SISEHRISSISVSP----PGDWIAFA 245
           +   +K+L T   SGL  L  +PD NL+HTL   +  + ++ SI  S     P D    +
Sbjct: 237 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTKKEQLHSIPKSTVSLDPKDVNLAS 296

Query: 246 CPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCF 305
           C   G + +W   S++ V   +GH++ +  + + P G  + T  +D   ++W+       
Sbjct: 297 CAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEI 356

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
           +    H   V  +    +     +  LD   R +DL   R    L    L +   +    
Sbjct: 357 LHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG-HLKEIYGINFSP 415

Query: 366 SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVR 425
           +G   A G  D     VW ++  + +  +  H+  V+ + F P +    L + ++D T +
Sbjct: 416 NGYHIATGSGD-NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEP-IHGNFLLTGAYDNTAK 473

Query: 426 LW 427
           +W
Sbjct: 474 IW 475



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 26/97 (26%), Positives = 41/97 (42%), Gaps = 10/97 (10%)

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCID-------REVQCEPIRLNS-DALQ 447
           G + P+S   FSP   S  LA+A W G  +LW   D       R    +  +L+S     
Sbjct: 227 GDDRPISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTKKEQLHSIPKST 284

Query: 448 VAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRS 484
           V+  P    +A    DG++  +   + E    +EG +
Sbjct: 285 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 321


>CR457105-1|CAG33386.1|  521|Homo sapiens PRPF4 protein.
          Length = 521

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTG 288
           R++ +   P G ++   C +    L W+ ++++ ++ Q+GHS+ +  +A+  DG    TG
Sbjct: 324 RVARVMWHPSGRFLGTTCYDRSWRL-WDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTG 382

Query: 289 GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFR 348
           G D   +VW+   G C +    H   + G+  S N     + S D T + +DL + R   
Sbjct: 383 GLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 442

Query: 349 TLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
           T+ +   +          G F   G  D     +W+      L+ L GHE  V  L  S 
Sbjct: 443 TIPAHQNLVTGVKFEPIHGNFLLTGAYD-NTAKIWTHPGWSPLKTLAGHEGKVMGLDISS 501

Query: 409 TLTSTRLASASWDGTVRLW 427
                 +A+ S+D T +LW
Sbjct: 502 --DGQLIATCSYDRTFKLW 518



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 12/243 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTL--------SISEHRISSISVSPPGDWIAF 244
           +   +K+L T   SGL  L  +PD NL+HTL        +I  H  S++S+ P    +A 
Sbjct: 238 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLA- 296

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C   G + +W   S++ V   +GH++ +  + + P G  + T  +D   ++W+      
Sbjct: 297 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 356

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            +    H   V  +    +     +  LD   R +DL   R    L    L +   +   
Sbjct: 357 ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG-HLKEIYGINFS 415

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G   A G  D     VW ++  + +  +  H+  V+ + F P +    L + ++D T 
Sbjct: 416 PNGYHIATGSGD-NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEP-IHGNFLLTGAYDNTA 473

Query: 425 RLW 427
           ++W
Sbjct: 474 KIW 476



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 10/97 (10%)

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP--- 452
           G + P+S   FSP   S  LA+A W G  +LW   D  +       N++   + F P   
Sbjct: 228 GDDRPISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKST 285

Query: 453 ---DGEEI--AVSTLDGNITFFEPSTCEQTGSVEGRS 484
              D +++  A    DG++  +   + E    +EG +
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 322


>BC007424-1|AAH07424.1|  521|Homo sapiens PRP4 pre-mRNA processing
           factor 4 homolog (yeast) protein.
          Length = 521

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTG 288
           R++ +   P G ++   C +    L W+ ++++ ++ Q+GHS+ +  +A+  DG    TG
Sbjct: 324 RVARVMWHPSGRFLGTTCYDRSWRL-WDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTG 382

Query: 289 GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFR 348
           G D   +VW+   G C +    H   + G+  S N     + S D T + +DL + R   
Sbjct: 383 GLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 442

Query: 349 TLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
           T+ +   +          G F   G  D     +W+      L+ L GHE  V  L  S 
Sbjct: 443 TIPAHQNLVTGVKFEPIHGNFLLTGAYD-NTAKIWTHPGWSPLKTLAGHEGKVMGLDISS 501

Query: 409 TLTSTRLASASWDGTVRLW 427
                 +A+ S+D T +LW
Sbjct: 502 --DGQLIATCSYDRTFKLW 518



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 12/243 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTL--------SISEHRISSISVSPPGDWIAF 244
           +   +K+L T   SGL  L  +PD NL+HTL        +I  H  S++S+ P    +A 
Sbjct: 238 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLA- 296

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C   G + +W   S++ V   +GH++ +  + + P G  + T  +D   ++W+      
Sbjct: 297 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 356

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            +    H   V  +    +     +  LD   R +DL   R    L    L +   +   
Sbjct: 357 ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG-HLKEIYGINFS 415

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G   A G  D     VW ++  + +  +  H+  V+ + F P +    L + ++D T 
Sbjct: 416 PNGYHIATGSGD-NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEP-IHGNFLLTGAYDNTA 473

Query: 425 RLW 427
           ++W
Sbjct: 474 KIW 476



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 10/97 (10%)

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP--- 452
           G + P+S   FSP   S  LA+A W G  +LW   D  +       N++   + F P   
Sbjct: 228 GDDRPISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKST 285

Query: 453 ---DGEEI--AVSTLDGNITFFEPSTCEQTGSVEGRS 484
              D +++  A    DG++  +   + E    +EG +
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 322


>BC001588-1|AAH01588.1|  522|Homo sapiens PRP4 pre-mRNA processing
           factor 4 homolog (yeast) protein.
          Length = 522

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTG 288
           R++ +   P G ++   C +    L W+ ++++ ++ Q+GHS+ +  +A+  DG    TG
Sbjct: 325 RVARVMWHPSGRFLGTTCYDRSWRL-WDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTG 383

Query: 289 GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFR 348
           G D   +VW+   G C +    H   + G+  S N     + S D T + +DL + R   
Sbjct: 384 GLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 443

Query: 349 TLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
           T+ +   +          G F   G  D     +W+      L+ L GHE  V  L  S 
Sbjct: 444 TIPAHQNLVTGVKFEPIHGNFLLTGAYD-NTAKIWTHPGWSPLKTLAGHEGKVMGLDISS 502

Query: 409 TLTSTRLASASWDGTVRLW 427
                 +A+ S+D T +LW
Sbjct: 503 --DGQLIATCSYDRTFKLW 519



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 12/243 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTL--------SISEHRISSISVSPPGDWIAF 244
           +   +K+L T   SGL  L  +PD NL+HTL        +I  H  S++S+ P    +A 
Sbjct: 239 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLA- 297

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C   G + +W   S++ V   +GH++ +  + + P G  + T  +D   ++W+      
Sbjct: 298 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 357

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            +    H   V  +    +     +  LD   R +DL   R    L    L +   +   
Sbjct: 358 ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG-HLKEIYGINFS 416

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G   A G  D     VW ++  + +  +  H+  V+ + F P +    L + ++D T 
Sbjct: 417 PNGYHIATGSGD-NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEP-IHGNFLLTGAYDNTA 474

Query: 425 RLW 427
           ++W
Sbjct: 475 KIW 477



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 10/97 (10%)

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP--- 452
           G + P+S   FSP   S  LA+A W G  +LW   D  +       N++   + F P   
Sbjct: 229 GDDRPISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKST 286

Query: 453 ---DGEEI--AVSTLDGNITFFEPSTCEQTGSVEGRS 484
              D +++  A    DG++  +   + E    +EG +
Sbjct: 287 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 323


>AY572489-1|AAS78572.1|  521|Homo sapiens 60 kDa U4/U6
           snRNP-specific spliceosomal protein protein.
          Length = 521

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTG 288
           R++ +   P G ++   C +    L W+ ++++ ++ Q+GHS+ +  +A+  DG    TG
Sbjct: 324 RVARVMWHPSGRFLGTTCYDRSWRL-WDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTG 382

Query: 289 GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFR 348
           G D   +VW+   G C +    H   + G+  S N     + S D T + +DL + R   
Sbjct: 383 GLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 442

Query: 349 TLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
           T+ +   +          G F   G  D     +W+      L+ L GHE  V  L  S 
Sbjct: 443 TIPAHQNLVTGVKFEPIHGNFLLTGAYD-NTAKIWTHPGWSPLKTLAGHEGKVMGLDISS 501

Query: 409 TLTSTRLASASWDGTVRLW 427
                 +A+ S+D T +LW
Sbjct: 502 --DGQLIATCSYDRTFKLW 518



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 12/243 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTL--------SISEHRISSISVSPPGDWIAF 244
           +   +K+L T   SGL  L  +PD NL+HTL        +I  H  S++S+ P    +A 
Sbjct: 238 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLA- 296

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C   G + +W   S++ V   +GH++ +  + + P G  + T  +D   ++W+      
Sbjct: 297 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 356

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            +    H   V  +    +     +  LD   R +DL   R    L    L +   +   
Sbjct: 357 ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG-HLKEIYGINFS 415

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G   A G  D     VW ++  + +  +  H+  V+ + F P +    L + ++D T 
Sbjct: 416 PNGYHIATGSGD-NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEP-IHGNFLLTGAYDNTA 473

Query: 425 RLW 427
           ++W
Sbjct: 474 KIW 476



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 10/97 (10%)

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP--- 452
           G + P+S   FSP   S  LA+A W G  +LW   D  +       N++   + F P   
Sbjct: 228 GDDRPISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKST 285

Query: 453 ---DGEEI--AVSTLDGNITFFEPSTCEQTGSVEGRS 484
              D +++  A    DG++  +   + E    +EG +
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 322


>AL449305-8|CAI10969.1|  521|Homo sapiens PRP4 pre-mRNA processing
           factor 4 homolog (yeast) protein.
          Length = 521

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTG 288
           R++ +   P G ++   C +    L W+ ++++ ++ Q+GHS+ +  +A+  DG    TG
Sbjct: 324 RVARVMWHPSGRFLGTTCYDRSWRL-WDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTG 382

Query: 289 GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFR 348
           G D   +VW+   G C +    H   + G+  S N     + S D T + +DL + R   
Sbjct: 383 GLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 442

Query: 349 TLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
           T+ +   +          G F   G  D     +W+      L+ L GHE  V  L  S 
Sbjct: 443 TIPAHQNLVTGVKFEPIHGNFLLTGAYD-NTAKIWTHPGWSPLKTLAGHEGKVMGLDISS 501

Query: 409 TLTSTRLASASWDGTVRLW 427
                 +A+ S+D T +LW
Sbjct: 502 --DGQLIATCSYDRTFKLW 518



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 12/243 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTL--------SISEHRISSISVSPPGDWIAF 244
           +   +K+L T   SGL  L  +PD NL+HTL        +I  H  S++S+ P    +A 
Sbjct: 238 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLA- 296

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C   G + +W   S++ V   +GH++ +  + + P G  + T  +D   ++W+      
Sbjct: 297 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 356

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            +    H   V  +    +     +  LD   R +DL   R    L    L +   +   
Sbjct: 357 ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG-HLKEIYGINFS 415

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G   A G  D     VW ++  + +  +  H+  V+ + F P +    L + ++D T 
Sbjct: 416 PNGYHIATGSGD-NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEP-IHGNFLLTGAYDNTA 473

Query: 425 RLW 427
           ++W
Sbjct: 474 KIW 476



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 10/97 (10%)

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP--- 452
           G + P+S   FSP   S  LA+A W G  +LW   D  +       N++   + F P   
Sbjct: 228 GDDRPISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKST 285

Query: 453 ---DGEEI--AVSTLDGNITFFEPSTCEQTGSVEGRS 484
              D +++  A    DG++  +   + E    +EG +
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 322


>AL449305-7|CAI10968.1|  522|Homo sapiens PRP4 pre-mRNA processing
           factor 4 homolog (yeast) protein.
          Length = 522

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTG 288
           R++ +   P G ++   C +    L W+ ++++ ++ Q+GHS+ +  +A+  DG    TG
Sbjct: 325 RVARVMWHPSGRFLGTTCYDRSWRL-WDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTG 383

Query: 289 GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFR 348
           G D   +VW+   G C +    H   + G+  S N     + S D T + +DL + R   
Sbjct: 384 GLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 443

Query: 349 TLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
           T+ +   +          G F   G  D     +W+      L+ L GHE  V  L  S 
Sbjct: 444 TIPAHQNLVTGVKFEPIHGNFLLTGAYD-NTAKIWTHPGWSPLKTLAGHEGKVMGLDISS 502

Query: 409 TLTSTRLASASWDGTVRLW 427
                 +A+ S+D T +LW
Sbjct: 503 --DGQLIATCSYDRTFKLW 519



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 12/243 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTL--------SISEHRISSISVSPPGDWIAF 244
           +   +K+L T   SGL  L  +PD NL+HTL        +I  H  S++S+ P    +A 
Sbjct: 239 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLA- 297

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C   G + +W   S++ V   +GH++ +  + + P G  + T  +D   ++W+      
Sbjct: 298 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 357

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            +    H   V  +    +     +  LD   R +DL   R    L    L +   +   
Sbjct: 358 ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG-HLKEIYGINFS 416

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G   A G  D     VW ++  + +  +  H+  V+ + F P +    L + ++D T 
Sbjct: 417 PNGYHIATGSGD-NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEP-IHGNFLLTGAYDNTA 474

Query: 425 RLW 427
           ++W
Sbjct: 475 KIW 477



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 10/97 (10%)

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP--- 452
           G + P+S   FSP   S  LA+A W G  +LW   D  +       N++   + F P   
Sbjct: 229 GDDRPISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKST 286

Query: 453 ---DGEEI--AVSTLDGNITFFEPSTCEQTGSVEGRS 484
              D +++  A    DG++  +   + E    +EG +
Sbjct: 287 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 323


>AF016369-1|AAC51925.1|  522|Homo sapiens U4/U6 small nuclear
           ribonucleoprotein hPrp4 protein.
          Length = 522

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTG 288
           R++ +   P G ++   C +    L W+ ++++ ++ Q+GHS+ +  +A+  DG    TG
Sbjct: 325 RVARVMWHPSGRFLGTTCYDRSWRL-WDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTG 383

Query: 289 GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFR 348
           G D   +VW+   G C +    H   + G+  S N     + S D T + +DL + R   
Sbjct: 384 GLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 443

Query: 349 TLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
           T+ +   +          G F   G  D     +W+      L+ L GHE  V  L  S 
Sbjct: 444 TIPAHQNLVTGVKFEPIHGNFLLTGAYD-NTAKIWTHPGWSPLKTLAGHEGKVMGLDISS 502

Query: 409 TLTSTRLASASWDGTVRLW 427
                 +A+ S+D T +LW
Sbjct: 503 --DGQLIATCSYDRTFKLW 519



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 12/243 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTL--------SISEHRISSISVSPPGDWIAF 244
           +   +K+L T   SGL  L  +PD NL+HTL        +I  H  S++S+ P    +A 
Sbjct: 239 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLA- 297

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C   G + +W   S++ V   +GH++ +  + + P G  + T  +D   ++W+      
Sbjct: 298 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 357

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            +    H   V  +    +     +  LD   R +DL   R    L    L +   +   
Sbjct: 358 ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG-HLKEIYGINFS 416

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G   A G  D     VW ++  + +  +  H+  V+ + F P +    L + ++D T 
Sbjct: 417 PNGYHIATGSGD-NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEP-IHGNFLLTGAYDNTA 474

Query: 425 RLW 427
           ++W
Sbjct: 475 KIW 477



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 10/97 (10%)

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP--- 452
           G + P+S   FSP   S  LA+A W G  +LW   D  +       N++   + F P   
Sbjct: 229 GDDRPISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKST 286

Query: 453 ---DGEEI--AVSTLDGNITFFEPSTCEQTGSVEGRS 484
              D +++  A    DG++  +   + E    +EG +
Sbjct: 287 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 323


>AF001687-1|AAB87640.1|  521|Homo sapiens U4/U6 snRNP 60 kDa protein
           protein.
          Length = 521

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTG 288
           R++ +   P G ++   C +    L W+ ++++ ++ Q+GHS+ +  +A+  DG    TG
Sbjct: 324 RVARVMWHPSGRFLGTTCYDRSWRL-WDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTG 382

Query: 289 GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFR 348
           G D   +VW+   G C +   +H   + G+  S N     + S D T + +DL + R   
Sbjct: 383 GLDAFGRVWDLRTGRCIMFLEDHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 442

Query: 349 TLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
           T+     +          G F   G  D     +W+      L+ L GHE  V  L  S 
Sbjct: 443 TIPPHQNLVTGVKFEPIHGNFLLTGAYD-NTAKIWTHPGWSPLKTLAGHEGKVMGLDISS 501

Query: 409 TLTSTRLASASWDGTVRLW 427
                 +A+ S+D T +LW
Sbjct: 502 --DGQLIATYSYDRTFKLW 518



 Score = 65.7 bits (153), Expect = 6e-10
 Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 12/243 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTL--------SISEHRISSISVSPPGDWIAF 244
           +   +K+L T   SGL  L  +PD NL+HTL        +I  H  S++S+ P    +A 
Sbjct: 238 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLA- 296

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C   G + +W   S++ V   +GH++ +  + + P G  + T  +D   ++W+      
Sbjct: 297 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 356

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            +    H   V  +    +     +  LD   R +DL   R    L    L +   +   
Sbjct: 357 ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFL-EDHLKEIYGINFS 415

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G   A G  D     VW ++  + +  +  H+  V+ + F P +    L + ++D T 
Sbjct: 416 PNGYHIATGSGD-NTCKVWDLRQRRCVYTIPPHQNLVTGVKFEP-IHGNFLLTGAYDNTA 473

Query: 425 RLW 427
           ++W
Sbjct: 474 KIW 476



 Score = 41.1 bits (92), Expect = 0.014
 Identities = 34/152 (22%), Positives = 61/152 (40%), Gaps = 2/152 (1%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           + +H++  L  TG       + ++     I  L      I  I+ SP G  IA    +  
Sbjct: 370 IAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEDHLKEIYGINFSPNGYHIATGSGD-N 428

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSP-DGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
              VW+ +  + V     H   +T + + P  G  ++TG +D   K+W         T  
Sbjct: 429 TCKVWDLRQRRCVYTIPPHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHPGWSPLKTLA 488

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
            H+  V G+  S++ +   + S D T + + L
Sbjct: 489 GHEGKVMGLDISSDGQLIATYSYDRTFKLWML 520



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 10/97 (10%)

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP--- 452
           G + P+S   FSP   S  LA+A W G  +LW   D  +       N++   + F P   
Sbjct: 228 GDDRPISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKST 285

Query: 453 ---DGEEI--AVSTLDGNITFFEPSTCEQTGSVEGRS 484
              D +++  A    DG++  +   + E    +EG +
Sbjct: 286 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 322


>AB209797-1|BAD93034.1|  537|Homo sapiens PRPF4 protein variant
           protein.
          Length = 537

 Score = 80.6 bits (190), Expect = 2e-14
 Identities = 51/199 (25%), Positives = 88/199 (44%), Gaps = 4/199 (2%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTG 288
           R++ +   P G ++   C +    L W+ ++++ ++ Q+GHS+ +  +A+  DG    TG
Sbjct: 340 RVARVMWHPSGRFLGTTCYDRSWRL-WDLEAQEEILHQEGHSMGVYDIAFHQDGSLAGTG 398

Query: 289 GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFR 348
           G D   +VW+   G C +    H   + G+  S N     + S D T + +DL + R   
Sbjct: 399 GLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGYHIATGSGDNTCKVWDLRQRRCVY 458

Query: 349 TLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
           T+ +   +          G F   G  D     +W+      L+ L GHE  V  L  S 
Sbjct: 459 TIPAHQNLVTGVKFEPIHGNFLLTGAYD-NTAKIWTHPGWSPLKTLAGHEGKVMGLDISS 517

Query: 409 TLTSTRLASASWDGTVRLW 427
                 +A+ S+D T +LW
Sbjct: 518 --DGQLIATCSYDRTFKLW 534



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/243 (23%), Positives = 104/243 (42%), Gaps = 12/243 (4%)

Query: 193 YHKENKLLVTGFSSGLFFLHEMPDVNLIHTL--------SISEHRISSISVSPPGDWIAF 244
           +   +K+L T   SGL  L  +PD NL+HTL        +I  H  S++S+ P    +A 
Sbjct: 254 FSPNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLA- 312

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +C   G + +W   S++ V   +GH++ +  + + P G  + T  +D   ++W+      
Sbjct: 313 SCAADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEE 372

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            +    H   V  +    +     +  LD   R +DL   R    L    L +   +   
Sbjct: 373 ILHQEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEG-HLKEIYGINFS 431

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            +G   A G  D     VW ++  + +  +  H+  V+ + F P +    L + ++D T 
Sbjct: 432 PNGYHIATGSGD-NTCKVWDLRQRRCVYTIPAHQNLVTGVKFEP-IHGNFLLTGAYDNTA 489

Query: 425 RLW 427
           ++W
Sbjct: 490 KIW 492



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 10/97 (10%)

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP--- 452
           G + P+S   FSP   S  LA+A W G  +LW   D  +       N++   + F P   
Sbjct: 244 GDDRPISYCHFSPN--SKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKST 301

Query: 453 ---DGEEI--AVSTLDGNITFFEPSTCEQTGSVEGRS 484
              D +++  A    DG++  +   + E    +EG +
Sbjct: 302 VSLDPKDVNLASCAADGSVKLWSLDSDEPVADIEGHT 338


>BT009800-1|AAP88802.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 3 protein.
          Length = 340

 Score = 79.8 bits (188), Expect = 3e-14
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D   LA SPD    ++G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N +   + S D + R +DL   +     +  S++   + VA   SG    A
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW     + + +L GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDSMKSERVGILSGHDNRVSCLGV--TADGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 48/253 (18%), Positives = 105/253 (41%), Gaps = 12/253 (4%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+ A+ +  ++KLLV+    G   + +    N +H + +    + + + +P G+++  AC
Sbjct: 57  KIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV--AC 114

Query: 247 PNIGQLL-VWEWQSEQYVMK----QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
             +  +  ++  +S +  +K       H+  ++C  +  D  ++VT   D    +W+   
Sbjct: 115 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDN-NIVTSSGDTTCALWDIET 173

Query: 302 GFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
           G     F  H      +  S +   F+S + D + + +D+      +T T       + +
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE-SDINAI 232

Query: 362 ALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               +GE    G  D     ++ ++  + L +   HE+ + S+       S RL  A +D
Sbjct: 233 CFFPNGEAICTGSDDA-SCRLFDLRADQEL-ICFSHESIICSITSVAFSLSGRLLFAGYD 290

Query: 422 G-TVRLWDCIDRE 433
                +WD +  E
Sbjct: 291 DFNCNVWDSMKSE 303



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 55/212 (25%), Positives = 84/212 (39%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + ++ D   +V+   DGK+ VW+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNF---RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
            F     LD     Y+L +R  N    R L++ +     C  LD +    ++G       
Sbjct: 111 -FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT---TC 166

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+ G+   V  GH     SLA SP        S + D + +LWD   RE  C    
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDF--NLFISGACDASAKLWDV--REGTCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+GE I   + D +   F+
Sbjct: 223 TGHESDINAICFFPNGEAICTGSDDASCRLFD 254


>BC002454-1|AAH02454.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 3 protein.
          Length = 340

 Score = 79.8 bits (188), Expect = 3e-14
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D   LA SPD    ++G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N +   + S D + R +DL   +     +  S++   + VA   SG    A
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW     + + +L GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDSMKSERVGILSGHDNRVSCLGV--TADGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 48/253 (18%), Positives = 105/253 (41%), Gaps = 12/253 (4%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+ A+ +  ++KLLV+    G   + +    N +H + +    + + + +P G+++  AC
Sbjct: 57  KIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV--AC 114

Query: 247 PNIGQLL-VWEWQSEQYVMK----QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
             +  +  ++  +S +  +K       H+  ++C  +  D  ++VT   D    +W+   
Sbjct: 115 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDN-NIVTSSGDTTCALWDIET 173

Query: 302 GFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
           G     F  H      +  S +   F+S + D + + +D+      +T T       + +
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE-SDINAI 232

Query: 362 ALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               +GE    G  D     ++ ++  + L +   HE+ + S+       S RL  A +D
Sbjct: 233 CFFPNGEAICTGSDDA-SCRLFDLRADQEL-ICFSHESIICSITSVAFSLSGRLLFAGYD 290

Query: 422 G-TVRLWDCIDRE 433
                +WD +  E
Sbjct: 291 DFNCNVWDSMKSE 303



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 55/212 (25%), Positives = 84/212 (39%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + ++ D   +V+   DGK+ VW+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNF---RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
            F     LD     Y+L +R  N    R L++ +     C  LD +    ++G       
Sbjct: 111 -FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT---TC 166

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+ G+   V  GH     SLA SP        S + D + +LWD   RE  C    
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDF--NLFISGACDASAKLWDV--REGTCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+GE I   + D +   F+
Sbjct: 223 TGHESDINAICFFPNGEAICTGSDDASCRLFD 254


>BC000115-1|AAH00115.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 3 protein.
          Length = 340

 Score = 79.8 bits (188), Expect = 3e-14
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D   LA SPD    ++G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N +   + S D + R +DL   +     +  S++   + VA   SG    A
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICSITSVAFSLSGRLLFA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW     + + +L GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDSMKSERVGILSGHDNRVSCLGV--TADGMAVATGSWDSFLKIWN 340



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 48/253 (18%), Positives = 105/253 (41%), Gaps = 12/253 (4%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+ A+ +  ++KLLV+    G   + +    N +H + +    + + + +P G+++  AC
Sbjct: 57  KIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV--AC 114

Query: 247 PNIGQLL-VWEWQSEQYVMK----QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
             +  +  ++  +S +  +K       H+  ++C  +  D  ++VT   D    +W+   
Sbjct: 115 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDN-NIVTSSGDTTCALWDIET 173

Query: 302 GFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
           G     F  H      +  S +   F+S + D + + +D+      +T T       + +
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE-SDINAI 232

Query: 362 ALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               +GE    G  D     ++ ++  + L +   HE+ + S+       S RL  A +D
Sbjct: 233 CFFPNGEAICTGSDDA-SCRLFDLRADQEL-ICFSHESIICSITSVAFSLSGRLLFAGYD 290

Query: 422 G-TVRLWDCIDRE 433
                +WD +  E
Sbjct: 291 DFNCNVWDSMKSE 303



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 55/212 (25%), Positives = 84/212 (39%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + ++ D   +V+   DGK+ VW+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNF---RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
            F     LD     Y+L +R  N    R L++ +     C  LD +    ++G       
Sbjct: 111 -FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT---TC 166

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+ G+   V  GH     SLA SP        S + D + +LWD   RE  C    
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDF--NLFISGACDASAKLWDV--REGTCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+GE I   + D +   F+
Sbjct: 223 TGHESDINAICFFPNGEAICTGSDDASCRLFD 254


>CR456762-1|CAG33043.1|  655|Homo sapiens KATNB1 protein.
          Length = 655

 Score = 79.4 bits (187), Expect = 4e-14
 Identities = 57/201 (28%), Positives = 88/201 (43%), Gaps = 4/201 (1%)

Query: 282 GLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
           G  + TGG D +V +W+     C ++   H + V  V  +  ++  V+ S  G++R +DL
Sbjct: 33  GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92

Query: 342 TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPV 401
              +  RTL          +     GEF A+G QD   I +W I+    +    GH   V
Sbjct: 93  EAAKILRTLMGHK-ANICSLDFHPYGEFVASGSQDT-NIKLWDIRRKGCVFRYRGHSQAV 150

Query: 402 SSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVST 461
             L FSP      LASA+ D TV+LWD    ++  E          V F P+   +A  +
Sbjct: 151 RCLRFSP--DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGS 208

Query: 462 LDGNITFFEPSTCEQTGSVEG 482
            D  I F++    +    +EG
Sbjct: 209 SDRTIRFWDLEKFQVVSCIEG 229



 Score = 79.4 bits (187), Expect = 4e-14
 Identities = 50/195 (25%), Positives = 92/195 (47%), Gaps = 4/195 (2%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           +V+ +   +L+V G  SG   + ++    ++ TL   +  I S+   P G+++A    + 
Sbjct: 68  SVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDT 127

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + +W+ + +  V + +GHS  + CL +SPDG  + +   D  VK+W+ T G     F 
Sbjct: 128 N-IKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP 186

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLT-SPSLVQFSCVALDSSGE 368
            H   V+ V    N+    S S D T+R +DL +++    +   P  V+   V  +  G 
Sbjct: 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVR--SVLFNPDGC 244

Query: 369 FCAAGGQDVFEIFVW 383
              +G QD   ++ W
Sbjct: 245 CLYSGCQDSLRVYGW 259



 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 54/223 (24%), Positives = 88/223 (39%), Gaps = 7/223 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W       +M   GH+  +  +  +     +V G   G ++VW+        T   HKA
Sbjct: 47  LWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKA 106

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYR-NFRTLTSPSLVQFSCVALDSSGEFCAA 372
            +  +      +F  S S D  ++ +D+ R    FR       V+  C+     G++ A+
Sbjct: 107 NICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVR--CLRFSPDGKWLAS 164

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
              D   + +W +  GK++    GH  PV+ + F P      LAS S D T+R WD    
Sbjct: 165 AADD-HTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP--NEYLLASGSSDRTIRFWDLEKF 221

Query: 433 EVQCEPIRLNSDALQVAFRPDGEEIAVSTLDG-NITFFEPSTC 474
           +V             V F PDG  +     D   +  +EP  C
Sbjct: 222 QVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERC 264



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 3/112 (2%)

Query: 359 SCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASA 418
           S V   +SG   A GG D   + +WSI     +  L GH +PV S+  +       + + 
Sbjct: 25  SLVLGKASGRLLATGGDDC-RVNLWSINKPNCIMSLTGHTSPVESVRLN--TPEELIVAG 81

Query: 419 SWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           S  G++R+WD    ++    +   ++   + F P GE +A  + D NI  ++
Sbjct: 82  SQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133


>BT007022-1|AAP35668.1|  655|Homo sapiens katanin p80
           (WD40-containing) subunit B 1 protein.
          Length = 655

 Score = 79.4 bits (187), Expect = 4e-14
 Identities = 57/201 (28%), Positives = 88/201 (43%), Gaps = 4/201 (1%)

Query: 282 GLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
           G  + TGG D +V +W+     C ++   H + V  V  +  ++  V+ S  G++R +DL
Sbjct: 33  GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92

Query: 342 TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPV 401
              +  RTL          +     GEF A+G QD   I +W I+    +    GH   V
Sbjct: 93  EAAKILRTLMGHK-ANICSLDFHPYGEFVASGSQDT-NIKLWDIRRKGCVFRYRGHSQAV 150

Query: 402 SSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVST 461
             L FSP      LASA+ D TV+LWD    ++  E          V F P+   +A  +
Sbjct: 151 RCLRFSP--DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGS 208

Query: 462 LDGNITFFEPSTCEQTGSVEG 482
            D  I F++    +    +EG
Sbjct: 209 SDRTIRFWDLEKFQVVSCIEG 229



 Score = 79.4 bits (187), Expect = 4e-14
 Identities = 50/195 (25%), Positives = 92/195 (47%), Gaps = 4/195 (2%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           +V+ +   +L+V G  SG   + ++    ++ TL   +  I S+   P G+++A    + 
Sbjct: 68  SVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDT 127

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + +W+ + +  V + +GHS  + CL +SPDG  + +   D  VK+W+ T G     F 
Sbjct: 128 N-IKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP 186

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLT-SPSLVQFSCVALDSSGE 368
            H   V+ V    N+    S S D T+R +DL +++    +   P  V+   V  +  G 
Sbjct: 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVR--SVLFNPDGC 244

Query: 369 FCAAGGQDVFEIFVW 383
              +G QD   ++ W
Sbjct: 245 CLYSGCQDSLRVYGW 259



 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 54/223 (24%), Positives = 88/223 (39%), Gaps = 7/223 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W       +M   GH+  +  +  +     +V G   G ++VW+        T   HKA
Sbjct: 47  LWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKA 106

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYR-NFRTLTSPSLVQFSCVALDSSGEFCAA 372
            +  +      +F  S S D  ++ +D+ R    FR       V+  C+     G++ A+
Sbjct: 107 NICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVR--CLRFSPDGKWLAS 164

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
              D   + +W +  GK++    GH  PV+ + F P      LAS S D T+R WD    
Sbjct: 165 AADD-HTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP--NEYLLASGSSDRTIRFWDLEKF 221

Query: 433 EVQCEPIRLNSDALQVAFRPDGEEIAVSTLDG-NITFFEPSTC 474
           +V             V F PDG  +     D   +  +EP  C
Sbjct: 222 QVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERC 264



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 3/112 (2%)

Query: 359 SCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASA 418
           S V   +SG   A GG D   + +WSI     +  L GH +PV S+  +       + + 
Sbjct: 25  SLVLGKASGRLLATGGDDC-RVNLWSINKPNCIMSLTGHTSPVESVRLN--TPEELIVAG 81

Query: 419 SWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           S  G++R+WD    ++    +   ++   + F P GE +A  + D NI  ++
Sbjct: 82  SQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133


>BC001353-1|AAH01353.1|  655|Homo sapiens katanin p80 (WD repeat
           containing) subunit B 1 protein.
          Length = 655

 Score = 79.4 bits (187), Expect = 4e-14
 Identities = 57/201 (28%), Positives = 88/201 (43%), Gaps = 4/201 (1%)

Query: 282 GLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
           G  + TGG D +V +W+     C ++   H + V  V  +  ++  V+ S  G++R +DL
Sbjct: 33  GRLLATGGDDCRVNLWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDL 92

Query: 342 TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPV 401
              +  RTL          +     GEF A+G QD   I +W I+    +    GH   V
Sbjct: 93  EAAKILRTLMGHK-ANICSLDFHPYGEFVASGSQDT-NIKLWDIRRKGCVFRYRGHSQAV 150

Query: 402 SSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVST 461
             L FSP      LASA+ D TV+LWD    ++  E          V F P+   +A  +
Sbjct: 151 RCLRFSP--DGKWLASAADDHTVKLWDLTAGKMMSEFPGHTGPVNVVEFHPNEYLLASGS 208

Query: 462 LDGNITFFEPSTCEQTGSVEG 482
            D  I F++    +    +EG
Sbjct: 209 SDRTIRFWDLEKFQVVSCIEG 229



 Score = 79.4 bits (187), Expect = 4e-14
 Identities = 50/195 (25%), Positives = 92/195 (47%), Gaps = 4/195 (2%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI 249
           +V+ +   +L+V G  SG   + ++    ++ TL   +  I S+   P G+++A    + 
Sbjct: 68  SVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDT 127

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + +W+ + +  V + +GHS  + CL +SPDG  + +   D  VK+W+ T G     F 
Sbjct: 128 N-IKLWDIRRKGCVFRYRGHSQAVRCLRFSPDGKWLASAADDHTVKLWDLTAGKMMSEFP 186

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLT-SPSLVQFSCVALDSSGE 368
            H   V+ V    N+    S S D T+R +DL +++    +   P  V+   V  +  G 
Sbjct: 187 GHTGPVNVVEFHPNEYLLASGSSDRTIRFWDLEKFQVVSCIEGEPGPVR--SVLFNPDGC 244

Query: 369 FCAAGGQDVFEIFVW 383
              +G QD   ++ W
Sbjct: 245 CLYSGCQDSLRVYGW 259



 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 54/223 (24%), Positives = 88/223 (39%), Gaps = 7/223 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W       +M   GH+  +  +  +     +V G   G ++VW+        T   HKA
Sbjct: 47  LWSINKPNCIMSLTGHTSPVESVRLNTPEELIVAGSQSGSIRVWDLEAAKILRTLMGHKA 106

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYR-NFRTLTSPSLVQFSCVALDSSGEFCAA 372
            +  +      +F  S S D  ++ +D+ R    FR       V+  C+     G++ A+
Sbjct: 107 NICSLDFHPYGEFVASGSQDTNIKLWDIRRKGCVFRYRGHSQAVR--CLRFSPDGKWLAS 164

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
              D   + +W +  GK++    GH  PV+ + F P      LAS S D T+R WD    
Sbjct: 165 AADD-HTVKLWDLTAGKMMSEFPGHTGPVNVVEFHP--NEYLLASGSSDRTIRFWDLEKF 221

Query: 433 EVQCEPIRLNSDALQVAFRPDGEEIAVSTLDG-NITFFEPSTC 474
           +V             V F PDG  +     D   +  +EP  C
Sbjct: 222 QVVSCIEGEPGPVRSVLFNPDGCCLYSGCQDSLRVYGWEPERC 264



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 30/112 (26%), Positives = 52/112 (46%), Gaps = 3/112 (2%)

Query: 359 SCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASA 418
           S V   +SG   A GG D   + +WSI     +  L GH +PV S+  +       + + 
Sbjct: 25  SLVLGKASGRLLATGGDDC-RVNLWSINKPNCIMSLTGHTSPVESVRLN--TPEELIVAG 81

Query: 419 SWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           S  G++R+WD    ++    +   ++   + F P GE +A  + D NI  ++
Sbjct: 82  SQSGSIRVWDLEAAKILRTLMGHKANICSLDFHPYGEFVASGSQDTNIKLWD 133


>Y12050-1|CAA72779.1|  340|Homo sapiens guanine nucleotide-binding
           protein beta3 subunit protein.
          Length = 340

 Score = 79.0 bits (186), Expect = 6e-14
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D   LA SPD    ++G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N +   + S D + R +DL   +     +  S++   + VA   SG    A
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW     + + +L GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDSMKSERVGILSGHDNRVSCLGV--TADGMAVATGSWDSFLKIWN 340



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 55/212 (25%), Positives = 84/212 (39%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + ++ D   +V+   DGK+ VW+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNF---RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
            F     LD     Y+L +R  N    R L++ +     C  LD +    ++G       
Sbjct: 111 -FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT---TC 166

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+ G+   V  GH     SLA SP        S + D + +LWD   RE  C    
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDF--NLFISGACDASAKLWDV--REGTCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+GE I   + D +   F+
Sbjct: 223 TGHESDINAICFFPNGEAICTGSDDASCRLFD 254



 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 47/253 (18%), Positives = 104/253 (41%), Gaps = 12/253 (4%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+ A+ +  ++KLLV+    G   + +    N +H + +    + + + +P G+++  AC
Sbjct: 57  KIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV--AC 114

Query: 247 PNIGQLL-VWEWQSEQYVMK----QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
             +  +  ++  +S +  +K       H+  ++C  +  D  ++VT   D    +W+   
Sbjct: 115 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDN-NIVTSSGDTTCALWDIET 173

Query: 302 GFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
           G     F  H      +  S +   F+S + D + + +D+      +T T       + +
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE-SDINAI 232

Query: 362 ALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               +GE    G  D     ++ ++  + L +   HE+ +  +       S RL  A +D
Sbjct: 233 CFFPNGEAICTGSDDA-SCRLFDLRADQEL-ICFSHESIICGITSVAFSLSGRLLFAGYD 290

Query: 422 G-TVRLWDCIDRE 433
                +WD +  E
Sbjct: 291 DFNCNVWDSMKSE 303


>U47924-5|AAB51313.1|  340|Homo sapiens G-protein beta-3 chain
           protein.
          Length = 340

 Score = 79.0 bits (186), Expect = 6e-14
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D   LA SPD    ++G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N +   + S D + R +DL   +     +  S++   + VA   SG    A
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW     + + +L GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDSMKSERVGILSGHDNRVSCLGV--TADGMAVATGSWDSFLKIWN 340



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 55/212 (25%), Positives = 84/212 (39%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + ++ D   +V+   DGK+ VW+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNF---RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
            F     LD     Y+L +R  N    R L++ +     C  LD +    ++G       
Sbjct: 111 -FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT---TC 166

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+ G+   V  GH     SLA SP        S + D + +LWD   RE  C    
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDF--NLFISGACDASAKLWDV--REGTCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+GE I   + D +   F+
Sbjct: 223 TGHESDINAICFFPNGEAICTGSDDASCRLFD 254



 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 47/253 (18%), Positives = 104/253 (41%), Gaps = 12/253 (4%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+ A+ +  ++KLLV+    G   + +    N +H + +    + + + +P G+++  AC
Sbjct: 57  KIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV--AC 114

Query: 247 PNIGQLL-VWEWQSEQYVMK----QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
             +  +  ++  +S +  +K       H+  ++C  +  D  ++VT   D    +W+   
Sbjct: 115 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDN-NIVTSSGDTTCALWDIET 173

Query: 302 GFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
           G     F  H      +  S +   F+S + D + + +D+      +T T       + +
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE-SDINAI 232

Query: 362 ALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               +GE    G  D     ++ ++  + L +   HE+ +  +       S RL  A +D
Sbjct: 233 CFFPNGEAICTGSDDA-SCRLFDLRADQEL-ICFSHESIICGITSVAFSLSGRLLFAGYD 290

Query: 422 G-TVRLWDCIDRE 433
                +WD +  E
Sbjct: 291 DFNCNVWDSMKSE 303


>M31328-1|AAA52582.1|  340|Homo sapiens GNB3 protein.
          Length = 340

 Score = 79.0 bits (186), Expect = 6e-14
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D   LA SPD    ++G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N +   + S D + R +DL   +     +  S++   + VA   SG    A
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW     + + +L GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDSMKSERVGILSGHDNRVSCLGV--TADGMAVATGSWDSFLKIWN 340



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 55/212 (25%), Positives = 84/212 (39%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + ++ D   +V+   DGK+ VW+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNF---RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
            F     LD     Y+L +R  N    R L++ +     C  LD +    ++G       
Sbjct: 111 -FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT---TC 166

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+ G+   V  GH     SLA SP        S + D + +LWD   RE  C    
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDF--NLFISGACDASAKLWDV--REGTCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+GE I   + D +   F+
Sbjct: 223 TGHESDINAICFFPNGEAICTGSDDASCRLFD 254



 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 47/253 (18%), Positives = 104/253 (41%), Gaps = 12/253 (4%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+ A+ +  ++KLLV+    G   + +    N +H + +    + + + +P G+++  AC
Sbjct: 57  KIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV--AC 114

Query: 247 PNIGQLL-VWEWQSEQYVMK----QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
             +  +  ++  +S +  +K       H+  ++C  +  D  ++VT   D    +W+   
Sbjct: 115 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDN-NIVTSSGDTTCALWDIET 173

Query: 302 GFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
           G     F  H      +  S +   F+S + D + + +D+      +T T       + +
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE-SDINAI 232

Query: 362 ALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               +GE    G  D     ++ ++  + L +   HE+ +  +       S RL  A +D
Sbjct: 233 CFFPNGEAICTGSDDA-SCRLFDLRADQEL-ICFSHESIICGITSVAFSLSGRLLFAGYD 290

Query: 422 G-TVRLWDCIDRE 433
                +WD +  E
Sbjct: 291 DFNCNVWDSMKSE 303


>AY631872-1|AAT38116.1|  340|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 3 protein.
          Length = 340

 Score = 79.0 bits (186), Expect = 6e-14
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D   LA SPD    ++G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N +   + S D + R +DL   +     +  S++   + VA   SG    A
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW     + + +L GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDSMKSERVGILSGHDNRVSCLGV--TADGMAVATGSWDSFLKIWN 340



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 55/212 (25%), Positives = 84/212 (39%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + ++ D   +V+   DGK+ VW+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNF---RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
            F     LD     Y+L +R  N    R L++ +     C  LD +    ++G       
Sbjct: 111 -FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT---TC 166

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+ G+   V  GH     SLA SP        S + D + +LWD   RE  C    
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDF--NLFISGACDASAKLWDV--REGTCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+GE I   + D +   F+
Sbjct: 223 TGHESDINAICFFPNGEAICTGSDDASCRLFD 254



 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 47/253 (18%), Positives = 104/253 (41%), Gaps = 12/253 (4%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+ A+ +  ++KLLV+    G   + +    N +H + +    + + + +P G+++  AC
Sbjct: 57  KIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV--AC 114

Query: 247 PNIGQLL-VWEWQSEQYVMK----QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
             +  +  ++  +S +  +K       H+  ++C  +  D  ++VT   D    +W+   
Sbjct: 115 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDN-NIVTSSGDTTCALWDIET 173

Query: 302 GFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
           G     F  H      +  S +   F+S + D + + +D+      +T T       + +
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE-SDINAI 232

Query: 362 ALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               +GE    G  D     ++ ++  + L +   HE+ +  +       S RL  A +D
Sbjct: 233 CFFPNGEAICTGSDDA-SCRLFDLRADQEL-ICFSHESIICGITSVAFSLSGRLLFAGYD 290

Query: 422 G-TVRLWDCIDRE 433
                +WD +  E
Sbjct: 291 DFNCNVWDSMKSE 303


>AF501884-1|AAM15920.1|  340|Homo sapiens guanine nucleotide binding
           protein beta 3 protein.
          Length = 340

 Score = 79.0 bits (186), Expect = 6e-14
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D   LA SPD    ++G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N +   + S D + R +DL   +     +  S++   + VA   SG    A
Sbjct: 228 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW     + + +L GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 288 GYDD-FNCNVWDSMKSERVGILSGHDNRVSCLGV--TADGMAVATGSWDSFLKIWN 340



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 55/212 (25%), Positives = 84/212 (39%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + ++ D   +V+   DGK+ VW+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNF---RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
            F     LD     Y+L +R  N    R L++ +     C  LD +    ++G       
Sbjct: 111 -FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT---TC 166

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+ G+   V  GH     SLA SP        S + D + +LWD   RE  C    
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDF--NLFISGACDASAKLWDV--REGTCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+GE I   + D +   F+
Sbjct: 223 TGHESDINAICFFPNGEAICTGSDDASCRLFD 254



 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 47/253 (18%), Positives = 104/253 (41%), Gaps = 12/253 (4%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+ A+ +  ++KLLV+    G   + +    N +H + +    + + + +P G+++  AC
Sbjct: 57  KIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV--AC 114

Query: 247 PNIGQLL-VWEWQSEQYVMK----QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
             +  +  ++  +S +  +K       H+  ++C  +  D  ++VT   D    +W+   
Sbjct: 115 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDN-NIVTSSGDTTCALWDIET 173

Query: 302 GFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
           G     F  H      +  S +   F+S + D + + +D+      +T T       + +
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE-SDINAI 232

Query: 362 ALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               +GE    G  D     ++ ++  + L +   HE+ +  +       S RL  A +D
Sbjct: 233 CFFPNGEAICTGSDDA-SCRLFDLRADQEL-ICFSHESIICGITSVAFSLSGRLLFAGYD 290

Query: 422 G-TVRLWDCIDRE 433
                +WD +  E
Sbjct: 291 DFNCNVWDSMKSE 303


>AB209283-1|BAD92520.1|  327|Homo sapiens guanine nucleotide-binding
           protein, beta-3 subunit variant protein.
          Length = 327

 Score = 79.0 bits (186), Expect = 6e-14
 Identities = 48/176 (27%), Positives = 81/176 (46%), Gaps = 4/176 (2%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D   LA SPD    ++G  D   K+W+   G C  TF  H++
Sbjct: 155 LWDIETGQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHES 214

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N +   + S D + R +DL   +     +  S++   + VA   SG    A
Sbjct: 215 DINAICFFPNGEAICTGSDDASCRLFDLRADQELICFSHESIICGITSVAFSLSGRLLFA 274

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           G  D F   VW     + + +L GH+  VS L    T     +A+ SWD  +++W+
Sbjct: 275 GYDD-FNCNVWDSMKSERVGILSGHDNRVSCLGV--TADGMAVATGSWDSFLKIWN 327



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 55/212 (25%), Positives = 84/212 (39%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + ++ D   +V+   DGK+ VW+  TTN    +              S N 
Sbjct: 39  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 97

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNF---RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
            F     LD     Y+L +R  N    R L++ +     C  LD +    ++G       
Sbjct: 98  -FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT---TC 153

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+ G+   V  GH     SLA SP        S + D + +LWD   RE  C    
Sbjct: 154 ALWDIETGQQKTVFVGHTGDCMSLAVSPDF--NLFISGACDASAKLWDV--REGTCRQTF 209

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+GE I   + D +   F+
Sbjct: 210 TGHESDINAICFFPNGEAICTGSDDASCRLFD 241



 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 47/253 (18%), Positives = 104/253 (41%), Gaps = 12/253 (4%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+ A+ +  ++KLLV+    G   + +    N +H + +    + + + +P G+++  AC
Sbjct: 44  KIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV--AC 101

Query: 247 PNIGQLL-VWEWQSEQYVMK----QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
             +  +  ++  +S +  +K       H+  ++C  +  D  ++VT   D    +W+   
Sbjct: 102 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDN-NIVTSSGDTTCALWDIET 160

Query: 302 GFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
           G     F  H      +  S +   F+S + D + + +D+      +T T       + +
Sbjct: 161 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHE-SDINAI 219

Query: 362 ALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               +GE    G  D     ++ ++  + L +   HE+ +  +       S RL  A +D
Sbjct: 220 CFFPNGEAICTGSDDA-SCRLFDLRADQEL-ICFSHESIICGITSVAFSLSGRLLFAGYD 277

Query: 422 G-TVRLWDCIDRE 433
                +WD +  E
Sbjct: 278 DFNCNVWDSMKSE 290


>CR457333-1|CAG33614.1|  305|Homo sapiens REC14 protein.
          Length = 305

 Score = 75.4 bits (177), Expect = 7e-13
 Identities = 60/276 (21%), Positives = 119/276 (43%), Gaps = 15/276 (5%)

Query: 195 KEN-KLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI-GQL 252
           KEN + +VTG    L  + +  D  L    S+  H++  +SV         A  ++   +
Sbjct: 29  KENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHI 88

Query: 253 LVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHK 312
            +W+ ++ + +       +D   LA+SPD  ++ TG   GKV ++   +G    +     
Sbjct: 89  RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148

Query: 313 ATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAA 372
             +  +  S + K+  S ++DG +  +D+   +   TL   ++     +      +    
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAM-PIRSLTFSPDSQLLVT 207

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD---- 428
              D + I ++ ++   L   LGGH + V ++AF P    T   S+S D  V++WD    
Sbjct: 208 ASDDGY-IKIYDVQHANLAGTLGGHASWVLNVAFCP--DDTHFVSSSSDKNVKVWDVGTR 264

Query: 429 -CI----DREVQCEPIRLNSDALQVAFRPDGEEIAV 459
            C+    D + Q   ++ N +  ++    D +EI +
Sbjct: 265 TCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI 300



 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 55/222 (24%), Positives = 97/222 (43%), Gaps = 6/222 (2%)

Query: 254 VWEWQSEQYVMKQ--QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           VW+W+ E+  ++   +GH L +  +  S       +   D  +++W+  NG    +    
Sbjct: 46  VWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAG 105

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
                 +  S + ++  + +  G V  + +   +   +L +      S +A    G++ A
Sbjct: 106 PVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILS-IAYSPDGKYLA 164

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCID 431
           +G  D   I ++ I  GKLL  L GH  P+ SL FSP   S  L +AS DG ++++D   
Sbjct: 165 SGAIDGI-INIFDIATGKLLHTLEGHAMPIRSLTFSPD--SQLLVTASDDGYIKIYDVQH 221

Query: 432 REVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPST 473
             +        S  L VAF PD      S+ D N+  ++  T
Sbjct: 222 ANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDVGT 263



 Score = 68.9 bits (161), Expect = 6e-11
 Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           + ++ Y  + K L +G   G+  + ++    L+HTL      I S++ SP    +  A  
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           + G + +++ Q         GH+  +  +A+ PD  H V+   D  VKVW+     C  T
Sbjct: 211 D-GYIKIYDVQHANLAGTLGGHASWVLNVAFCPDDTHFVSSSSDKNVKVWDVGTRTCVHT 269

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
           F +H+  V GV  + N    VS   D  +  YD
Sbjct: 270 FFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302



 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 38/200 (19%), Positives = 89/200 (44%), Gaps = 9/200 (4%)

Query: 232 SISVSPPGDWIAFACPNIGQLLVWEWQS--EQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           +++ SP   ++A    ++G++ ++  +S  ++Y +  +G  +    +AYSPDG ++ +G 
Sbjct: 111 TLAFSPDSQYLATGT-HVGKVNIFGVESGKKEYSLDTRGKFI--LSIAYSPDGKYLASGA 167

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT 349
            DG + +++   G    T   H   +  +T S + +  V++S DG ++ YD+       T
Sbjct: 168 IDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGT 227

Query: 350 LTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPT 409
           L   +    +         F ++       + VW +     +     H+  V  + ++  
Sbjct: 228 LGGHASWVLNVAFCPDDTHFVSSSSDK--NVKVWDVGTRTCVHTFFDHQDQVWGVKYNG- 284

Query: 410 LTSTRLASASWDGTVRLWDC 429
              +++ S   D  + ++DC
Sbjct: 285 -NGSKIVSVGDDQEIHIYDC 303



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 48/190 (25%), Positives = 82/190 (43%), Gaps = 12/190 (6%)

Query: 302 GFCFVTFHEHKATVSGVTCSANKK----FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV- 356
           G  F     H   +  V    NKK      V+ SLD  V+ +   ++R+ R     SL  
Sbjct: 6   GILFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVW---KWRDERLDLQWSLEG 62

Query: 357 -QFSCVALDSSGEFCAAGGQDV-FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR 414
            Q   V++D S     A    +   I +W ++ GK ++ +        +LAFSP   S  
Sbjct: 63  HQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPD--SQY 120

Query: 415 LASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTC 474
           LA+ +  G V ++     + +          L +A+ PDG+ +A   +DG I  F+ +T 
Sbjct: 121 LATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATG 180

Query: 475 EQTGSVEGRS 484
           +   ++EG +
Sbjct: 181 KLLHTLEGHA 190


>M24194-1|AAA59626.1|  317|Homo sapiens MHC B complex protein 12.3
           protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>CR541909-1|CAG46707.1|  317|Homo sapiens GNB2L1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>CR456978-1|CAG33259.1|  317|Homo sapiens GNB2L1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC117246-1|AAI17247.1|  707|Homo sapiens F-box and WD repeat domain
           containing 7 protein.
          Length = 707

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 483 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 540

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 541 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 595

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 596 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 650



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 525 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 582

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 583 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 640

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 641 SDD-GTVKLWDLKTGEFIRNL 660



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 434 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 491

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 492 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 547

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 548 QFD----GIHVVSGSLDTSIRVWD 567



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 384 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 438

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 439 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 494

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 495 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 548

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 549 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 586



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 507 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 560

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 561 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 618

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 619 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 662


>BC117244-1|AAI17245.1|  707|Homo sapiens F-box and WD repeat domain
           containing 7 protein.
          Length = 707

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 483 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 540

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 541 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 595

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 596 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 650



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 525 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 582

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 583 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 640

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 641 SDD-GTVKLWDLKTGEFIRNL 660



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 434 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 491

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 492 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 547

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 548 QFD----GIHVVSGSLDTSIRVWD 567



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 384 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 438

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 439 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 494

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 495 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 548

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 549 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 586



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 507 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 560

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 561 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 618

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 619 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 662


>BC114618-1|AAI14619.1|  332|Homo sapiens GNB1 protein protein.
          Length = 332

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 43/152 (28%), Positives = 69/152 (45%), Gaps = 2/152 (1%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+ ++ Q      GH+ D+  L+ +PD    V+G  D   K+W+   G C  TF  H++
Sbjct: 168 LWDIETGQQTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHES 227

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV-QFSCVALDSSGEFCAA 372
            ++ +    N   F + S D T R +DL   +   T +  +++   + V+   SG    A
Sbjct: 228 DINAICFFPNGNAFATGSDDATCRLFDLRADQELMTYSHDNIICGITSVSFSKSGRLLLA 287

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           G  D F   VW         VL GH+  VS L
Sbjct: 288 GYDD-FNCNVWDALKADRAGVLAGHDNRVSCL 318



 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 46/248 (18%), Positives = 104/248 (41%), Gaps = 8/248 (3%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFA- 245
           K+ A+ +  +++LLV+    G   + +    N +H + +    + + + +P G+++A   
Sbjct: 57  KIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGNYVACGG 116

Query: 246 CPNIGQLLVWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
             NI  +   + +     + ++  GH+  ++C  +  D   +VT   D    +W+   G 
Sbjct: 117 LDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDN-QIVTSSGDTTCALWDIETGQ 175

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
              TF  H   V  ++ + + + FVS + D + + +D+      +T T       + +  
Sbjct: 176 QTTTFTGHTGDVMSLSLAPDTRLFVSGACDASAKLWDVREGMCRQTFTGHE-SDINAICF 234

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDG- 422
             +G   A G  D     ++ ++  + L +   H+  +  +       S RL  A +D  
Sbjct: 235 FPNGNAFATGSDDA-TCRLFDLRADQEL-MTYSHDNIICGITSVSFSKSGRLLLAGYDDF 292

Query: 423 TVRLWDCI 430
              +WD +
Sbjct: 293 NCNVWDAL 300



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 52/212 (24%), Positives = 79/212 (37%), Gaps = 17/212 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + +  D   +V+   DGK+ +W+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWGTDSRLLVSASQDGKLIIWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNFRTL--TSPSLVQFSCVALDSSGEFCAAGGQDVFEIF 381
            +     LD     Y+L TR  N R     +      SC       +   + G     + 
Sbjct: 111 -YVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSCCRFLDDNQIVTSSGDTTCAL- 168

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRL-ASASWDGTVRLWDCIDREVQCEPIR 440
            W I+ G+      GH   V SL+ +P    TRL  S + D + +LWD   RE  C    
Sbjct: 169 -WDIETGQQTTTFTGHTGDVMSLSLAP---DTRLFVSGACDASAKLWDV--REGMCRQTF 222

Query: 441 L--NSDALQVAFRPDGEEIAVSTLDGNITFFE 470
               SD   + F P+G   A  + D     F+
Sbjct: 223 TGHESDINAICFFPNGNAFATGSDDATCRLFD 254


>BC037320-1|AAH37320.1|  621|Homo sapiens FBXW7 protein protein.
          Length = 621

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 397 LRVWDIETGQCLHVLMGHVAAVRCVRY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 454

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 455 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 509

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 510 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 564



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 439 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 496

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 497 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 554

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 555 SDD-GTVKLWDLKTGEFIRNL 574



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 348 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 405

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 406 QCLHVLMG-HVAAVRCVRYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 461

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 462 QFD----GIHVVSGSLDTSIRVWD 481



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 298 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 352

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 353 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 408

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 409 HVLMGHVAAVRCVRYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 462

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 463 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 500



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 39/135 (28%), Positives = 61/135 (45%), Gaps = 8/135 (5%)

Query: 220 IHTLSISEHRISSISVSPPGDWIAFACPNIG-QLLVWEWQSEQYVMKQQGHSLDMTCLAY 278
           +HTL    +R+ S+      D I     ++   + VW+ ++   +    GH   +T    
Sbjct: 448 LHTLQGHTNRVYSLQF----DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQ-SLTSGME 502

Query: 279 SPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC-SANKKFFVSSSLDGTVR 337
             D + +V+G  D  VK+W+   G C  T        S VTC   NK F ++SS DGTV+
Sbjct: 503 LKDNI-LVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVK 561

Query: 338 CYDLTRYRNFRTLTS 352
            +DL      R L +
Sbjct: 562 LWDLKTGEFIRNLVT 576


>BC032006-1|AAH32006.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC021993-1|AAH21993.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC019362-1|AAH19362.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC019093-1|AAH19093.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC017287-1|AAH17287.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC014788-1|AAH14788.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC014256-1|AAH14256.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC010119-1|AAH10119.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC000366-1|AAH00366.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC000214-1|AAH00214.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 protein.
          Length = 317

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 232



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>AY159316-1|AAO21313.1|  347|Homo sapiens lung cancer oncogene 7
           protein.
          Length = 347

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 56/205 (27%), Positives = 96/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 94  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 152

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 153 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 211

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W +  GK L  L G +  +++
Sbjct: 212 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDLNEGKHLYTLDGGDI-INA 268

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 269 LCFSP---NRYWLCAATGPSIKIWD 290



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 90  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 149

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 150 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 208

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 209 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 250



 Score = 56.8 bits (131), Expect = 3e-07
 Identities = 54/223 (24%), Positives = 94/223 (42%), Gaps = 9/223 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 42  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 101

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 102 SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 159

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 160 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 219

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                   V   PDG   A    DG    ++ +  +   +++G
Sbjct: 220 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDG 262



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 225 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 283

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 284 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 343

Query: 301 NG 302
            G
Sbjct: 344 IG 345


>AY049984-1|AAL07271.1|  707|Homo sapiens F-box protein CDC4
           protein.
          Length = 707

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 483 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 540

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 541 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 595

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 596 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 650



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 525 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 582

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 583 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 640

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 641 SDD-GTVKLWDLKTGEFIRNL 660



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 434 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 491

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 492 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 547

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 548 QFD----GIHVVSGSLDTSIRVWD 567



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 384 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 438

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 439 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 494

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 495 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 548

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 549 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 586



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 507 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 560

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 561 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 618

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 619 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 662


>AY033553-1|AAK57547.1|  627|Homo sapiens F-box protein FBW7
           protein.
          Length = 627

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 403 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 460

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 461 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 515

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 516 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 570



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 445 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 502

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 503 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 560

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 561 SDD-GTVKLWDLKTGEFIRNL 580



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 354 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 411

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 412 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 467

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 468 QFD----GIHVVSGSLDTSIRVWD 487



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 304 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 358

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 359 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 414

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 415 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 468

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 469 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 506



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 427 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 480

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 481 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 538

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 539 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 582


>AY008274-1|AAG16640.1|  589|Homo sapiens F-box protein SEL10
           protein.
          Length = 589

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 365 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 422

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 423 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 477

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 478 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 532



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 407 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 464

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 465 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 522

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 523 SDD-GTVKLWDLKTGEFIRNL 542



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 316 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 373

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 374 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 429

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 430 QFD----GIHVVSGSLDTSIRVWD 449



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 266 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 320

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 321 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 376

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 377 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 430

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 431 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 468



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 389 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 442

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 443 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 500

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 501 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 544


>AK223449-1|BAD97169.1|  627|Homo sapiens F-box protein FBW7 isoform
           2 variant protein.
          Length = 627

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 403 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 460

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 461 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 515

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 516 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 570



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 445 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 502

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 503 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 560

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 561 SDD-GTVKLWDLKTGEFIRNL 580



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 354 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 411

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 412 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 467

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 468 QFD----GIHVVSGSLDTSIRVWD 487



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 304 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 358

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 359 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 414

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 415 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 468

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 469 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 506



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 427 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 480

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 481 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 538

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 539 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 582


>AK001933-1|BAA91986.1|  553|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11071 fis, clone PLACE1004937, moderately
           similar to SEL-10 PROTEIN. ).
          Length = 553

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 329 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 386

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 387 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 441

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 442 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 496



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 371 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 428

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 429 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 486

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 487 SDD-GTVKLWDLKTGEFIRNL 506



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 280 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 337

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 338 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 393

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 394 QFD----GIHVVSGSLDTSIRVWD 413



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 230 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 284

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 285 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 340

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 341 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 394

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 395 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 432



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 353 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 406

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 407 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 464

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 465 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 508


>AF411972-1|AAL06291.1|  627|Homo sapiens archipelago beta form
           protein.
          Length = 627

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 403 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 460

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 461 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 515

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 516 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 570



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 445 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 502

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 503 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 560

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 561 SDD-GTVKLWDLKTGEFIRNL 580



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 354 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 411

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 412 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 467

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 468 QFD----GIHVVSGSLDTSIRVWD 487



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 304 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 358

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 359 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 414

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 415 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 468

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 469 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 506



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 427 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 480

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 481 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 538

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 539 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 582


>AF411971-1|AAL06290.1|  707|Homo sapiens archipelago alpha form
           protein.
          Length = 707

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 483 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 540

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 541 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 595

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 596 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 650



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 525 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 582

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 583 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 640

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 641 SDD-GTVKLWDLKTGEFIRNL 660



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 434 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 491

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 492 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 547

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 548 QFD----GIHVVSGSLDTSIRVWD 567



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 384 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 438

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 439 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 494

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 495 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 548

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 549 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 586



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 507 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 560

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 561 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 618

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 619 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 662


>AF383178-1|AAK60269.1|  561|Homo sapiens F-box protein FBX30
           protein.
          Length = 561

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 337 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 394

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 395 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 449

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 450 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 504



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 379 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 436

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 437 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 494

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 495 SDD-GTVKLWDLKTGEFIRNL 514



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 288 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 345

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 346 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 401

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 402 QFD----GIHVVSGSLDTSIRVWD 421



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 238 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 292

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 293 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 348

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 349 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 402

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 403 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 440



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 361 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 414

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 415 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 472

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 473 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 516


>AB209725-1|BAD92962.1|  624|Homo sapiens F-box protein FBW7 isoform
           2 variant protein.
          Length = 624

 Score = 73.7 bits (173), Expect = 2e-12
 Identities = 55/180 (30%), Positives = 83/180 (46%), Gaps = 15/180 (8%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L VW+ ++ Q +    GH   + C+ Y  DG  VV+G +D  VKVW+     C  T   H
Sbjct: 400 LRVWDIETGQCLHVLMGHVAAVRCVQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGH 457

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
              V   +   +    VS SLD ++R +D+       TLT     Q     ++       
Sbjct: 458 TNRV--YSLQFDGIHVVSGSLDTSIRVWDVETGNCIHTLTGH---QSLTSGMELKDNILV 512

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGG---HEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +G  D   + +W IK G+ L+ L G   H++ V+ L F+     T    +S DGTV+LWD
Sbjct: 513 SGNAD-STVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVIT----SSDDGTVKLWD 567



 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 40/141 (28%), Positives = 69/141 (48%), Gaps = 5/141 (3%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW+ ++E  +   QGH+  +  L +  DG+HVV+G  D  ++VW+   G C  T   H++
Sbjct: 442 VWDPETETCLHTLQGHTNRVYSLQF--DGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQS 499

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
             SG+    N    VS + D TV+ +D+   +  +TL  P+  Q +   L  +  F    
Sbjct: 500 LTSGMELKDN--ILVSGNADSTVKIWDIKTGQCLQTLQGPNKHQSAVTCLQFNKNFVITS 557

Query: 374 GQDVFEIFVWSIKFGKLLEVL 394
             D   + +W +K G+ +  L
Sbjct: 558 SDD-GTVKLWDLKTGEFIRNL 577



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 44/144 (30%), Positives = 64/144 (44%), Gaps = 10/144 (6%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  +KVWN   G C  T + H +TV       ++K  VS S D T+R +D+   
Sbjct: 351 IISGSTDRTLKVWNAETGECIHTLYGHTSTVR--CMHLHEKRVVSGSRDATLRVWDIETG 408

Query: 345 RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSL 404
           +    L    +    CV  D  G    +G  D F + VW  +    L  L GH   V SL
Sbjct: 409 QCLHVLMG-HVAAVRCVQYD--GRRVVSGAYD-FMVKVWDPETETCLHTLQGHTNRVYSL 464

Query: 405 AFSPTLTSTRLASASWDGTVRLWD 428
            F        + S S D ++R+WD
Sbjct: 465 QFD----GIHVVSGSLDTSIRVWD 484



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/218 (25%), Positives = 98/218 (44%), Gaps = 16/218 (7%)

Query: 273 MTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK-KFFVSSS 331
           +TCL +   G  +V+G  D  +KVW+   G C  T   H     GV  S  +    +S S
Sbjct: 301 ITCLQFC--GNRIVSGSDDNTLKVWSAVTGKCLRTLVGH---TGGVWSSQMRDNIIISGS 355

Query: 332 LDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL 391
            D T++ ++        TL   +     C+ L    +   +G +D   + VW I+ G+ L
Sbjct: 356 TDRTLKVWNAETGECIHTLYGHTST-VRCMHLHE--KRVVSGSRDA-TLRVWDIETGQCL 411

Query: 392 EVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFR 451
            VL GH A V  + +       R+ S ++D  V++WD  + E     ++ +++ +  + +
Sbjct: 412 HVLMGHVAAVRCVQYD----GRRVVSGAYDFMVKVWD-PETETCLHTLQGHTNRV-YSLQ 465

Query: 452 PDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSG 489
            DG  +   +LD +I  ++  T     ++ G   L SG
Sbjct: 466 FDGIHVVSGSLDTSIRVWDVETGNCIHTLTGHQSLTSG 503



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 10/164 (6%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           VQY  + + +V+G    +  + +      +HTL    +R+ S+      D I     ++ 
Sbjct: 424 VQY--DGRRVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQF----DGIHVVSGSLD 477

Query: 251 -QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             + VW+ ++   +    GH   +T      D + +V+G  D  VK+W+   G C  T  
Sbjct: 478 TSIRVWDVETGNCIHTLTGHQ-SLTSGMELKDNI-LVSGNADSTVKIWDIKTGQCLQTLQ 535

Query: 310 EHKATVSGVTC-SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTS 352
                 S VTC   NK F ++SS DGTV+ +DL      R L +
Sbjct: 536 GPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT 579


>BC010080-1|AAH10080.1|  305|Homo sapiens WD repeat domain 61
           protein.
          Length = 305

 Score = 73.3 bits (172), Expect = 3e-12
 Identities = 59/276 (21%), Positives = 119/276 (43%), Gaps = 15/276 (5%)

Query: 195 KEN-KLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI-GQL 252
           KEN + +VTG    L  + +  D  L    S+  H++  +SV         A  ++   +
Sbjct: 29  KENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHI 88

Query: 253 LVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHK 312
            +W+ ++ + +       +D   LA+SPD  ++ TG   GKV ++   +G    +     
Sbjct: 89  RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148

Query: 313 ATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAA 372
             +  +  S + K+  S ++DG +  +D+   +   TL   ++     +      +    
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAM-PIRSLTFSPDSQLLVT 207

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD---- 428
              D + I ++ ++   L   L GH + V ++AF P    T   S+S D +V++WD    
Sbjct: 208 ASDDGY-IKIYDVQHANLAGTLSGHASWVLNVAFCP--DDTHFVSSSSDKSVKVWDVGTR 264

Query: 429 -CI----DREVQCEPIRLNSDALQVAFRPDGEEIAV 459
            C+    D + Q   ++ N +  ++    D +EI +
Sbjct: 265 TCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI 300



 Score = 69.7 bits (163), Expect = 3e-11
 Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           + ++ Y  + K L +G   G+  + ++    L+HTL      I S++ SP    +  A  
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           + G + +++ Q         GH+  +  +A+ PD  H V+   D  VKVW+     C  T
Sbjct: 211 D-GYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
           F +H+  V GV  + N    VS   D  +  YD
Sbjct: 270 FFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302



 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 38/200 (19%), Positives = 90/200 (45%), Gaps = 9/200 (4%)

Query: 232 SISVSPPGDWIAFACPNIGQLLVWEWQS--EQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           +++ SP   ++A    ++G++ ++  +S  ++Y +  +G  +    +AYSPDG ++ +G 
Sbjct: 111 TLAFSPDSQYLATGT-HVGKVNIFGVESGKKEYSLDTRGKFI--LSIAYSPDGKYLASGA 167

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT 349
            DG + +++   G    T   H   +  +T S + +  V++S DG ++ YD+       T
Sbjct: 168 IDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGT 227

Query: 350 LTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPT 409
           L+  +    +         F ++       + VW +     +     H+  V  + ++  
Sbjct: 228 LSGHASWVLNVAFCPDDTHFVSSSSDK--SVKVWDVGTRTCVHTFFDHQDQVWGVKYNG- 284

Query: 410 LTSTRLASASWDGTVRLWDC 429
              +++ S   D  + ++DC
Sbjct: 285 -NGSKIVSVGDDQEIHIYDC 303



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 48/190 (25%), Positives = 82/190 (43%), Gaps = 12/190 (6%)

Query: 302 GFCFVTFHEHKATVSGVTCSANKK----FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV- 356
           G  F     H   +  V    NKK      V+ SLD  V+ +   ++R+ R     SL  
Sbjct: 6   GILFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVW---KWRDERLDLQWSLEG 62

Query: 357 -QFSCVALDSSGEFCAAGGQDV-FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR 414
            Q   V++D S     A    +   I +W ++ GK ++ +        +LAFSP   S  
Sbjct: 63  HQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPD--SQY 120

Query: 415 LASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTC 474
           LA+ +  G V ++     + +          L +A+ PDG+ +A   +DG I  F+ +T 
Sbjct: 121 LATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATG 180

Query: 475 EQTGSVEGRS 484
           +   ++EG +
Sbjct: 181 KLLHTLEGHA 190


>AK024754-1|BAB14986.1|  305|Homo sapiens protein ( Homo sapiens
           cDNA: FLJ21101 fis, clone CAS04682. ).
          Length = 305

 Score = 73.3 bits (172), Expect = 3e-12
 Identities = 59/276 (21%), Positives = 119/276 (43%), Gaps = 15/276 (5%)

Query: 195 KEN-KLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI-GQL 252
           KEN + +VTG    L  + +  D  L    S+  H++  +SV         A  ++   +
Sbjct: 29  KENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHI 88

Query: 253 LVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHK 312
            +W+ ++ + +       +D   LA+SPD  ++ TG   GKV ++   +G    +     
Sbjct: 89  RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148

Query: 313 ATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAA 372
             +  +  S + K+  S ++DG +  +D+   +   TL   ++     +      +    
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAM-PIRSLTFSPDSQLLVT 207

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD---- 428
              D + I ++ ++   L   L GH + V ++AF P    T   S+S D +V++WD    
Sbjct: 208 ASDDGY-IKIYDVQHANLAGTLSGHASWVLNVAFCP--DDTHFVSSSSDKSVKVWDVGTR 264

Query: 429 -CI----DREVQCEPIRLNSDALQVAFRPDGEEIAV 459
            C+    D + Q   ++ N +  ++    D +EI +
Sbjct: 265 TCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI 300



 Score = 69.7 bits (163), Expect = 3e-11
 Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           + ++ Y  + K L +G   G+  + ++    L+HTL      I S++ SP    +  A  
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           + G + +++ Q         GH+  +  +A+ PD  H V+   D  VKVW+     C  T
Sbjct: 211 D-GYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
           F +H+  V GV  + N    VS   D  +  YD
Sbjct: 270 FFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302



 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 38/200 (19%), Positives = 90/200 (45%), Gaps = 9/200 (4%)

Query: 232 SISVSPPGDWIAFACPNIGQLLVWEWQS--EQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           +++ SP   ++A    ++G++ ++  +S  ++Y +  +G  +    +AYSPDG ++ +G 
Sbjct: 111 TLAFSPDSQYLATGT-HVGKVNIFGVESGKKEYSLDTRGKFI--LSIAYSPDGKYLASGA 167

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT 349
            DG + +++   G    T   H   +  +T S + +  V++S DG ++ YD+       T
Sbjct: 168 IDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGT 227

Query: 350 LTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPT 409
           L+  +    +         F ++       + VW +     +     H+  V  + ++  
Sbjct: 228 LSGHASWVLNVAFCPDDTHFVSSSSDK--SVKVWDVGTRTCVHTFFDHQDQVWGVKYNG- 284

Query: 410 LTSTRLASASWDGTVRLWDC 429
              +++ S   D  + ++DC
Sbjct: 285 -NGSKIVSVGDDQEIHIYDC 303



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 48/190 (25%), Positives = 82/190 (43%), Gaps = 12/190 (6%)

Query: 302 GFCFVTFHEHKATVSGVTCSANKK----FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV- 356
           G  F     H   +  V    NKK      V+ SLD  V+ +   ++R+ R     SL  
Sbjct: 6   GILFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVW---KWRDERLDLQWSLEG 62

Query: 357 -QFSCVALDSSGEFCAAGGQDV-FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR 414
            Q   V++D S     A    +   I +W ++ GK ++ +        +LAFSP   S  
Sbjct: 63  HQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPD--SQY 120

Query: 415 LASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTC 474
           LA+ +  G V ++     + +          L +A+ PDG+ +A   +DG I  F+ +T 
Sbjct: 121 LATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATG 180

Query: 475 EQTGSVEGRS 484
           +   ++EG +
Sbjct: 181 KLLHTLEGHA 190


>AF309553-1|AAG31639.1|  305|Homo sapiens meiotic recombination
           protein REC14 protein.
          Length = 305

 Score = 73.3 bits (172), Expect = 3e-12
 Identities = 59/276 (21%), Positives = 119/276 (43%), Gaps = 15/276 (5%)

Query: 195 KEN-KLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI-GQL 252
           KEN + +VTG    L  + +  D  L    S+  H++  +SV         A  ++   +
Sbjct: 29  KENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHI 88

Query: 253 LVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHK 312
            +W+ ++ + +       +D   LA+SPD  ++ TG   GKV ++   +G    +     
Sbjct: 89  RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148

Query: 313 ATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAA 372
             +  +  S + K+  S ++DG +  +D+   +   TL   ++     +      +    
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAM-PIRSLTFSPDSQLLVT 207

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD---- 428
              D + I ++ ++   L   L GH + V ++AF P    T   S+S D +V++WD    
Sbjct: 208 ASDDGY-IKIYDVQHANLAGTLSGHASWVLNVAFCP--DDTHFVSSSSDKSVKVWDVGTR 264

Query: 429 -CI----DREVQCEPIRLNSDALQVAFRPDGEEIAV 459
            C+    D + Q   ++ N +  ++    D +EI +
Sbjct: 265 TCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI 300



 Score = 69.7 bits (163), Expect = 3e-11
 Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           + ++ Y  + K L +G   G+  + ++    L+HTL      I S++ SP    +  A  
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           + G + +++ Q         GH+  +  +A+ PD  H V+   D  VKVW+     C  T
Sbjct: 211 D-GYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
           F +H+  V GV  + N    VS   D  +  YD
Sbjct: 270 FFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302



 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 38/200 (19%), Positives = 90/200 (45%), Gaps = 9/200 (4%)

Query: 232 SISVSPPGDWIAFACPNIGQLLVWEWQS--EQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           +++ SP   ++A    ++G++ ++  +S  ++Y +  +G  +    +AYSPDG ++ +G 
Sbjct: 111 TLAFSPDSQYLATGT-HVGKVNIFGVESGKKEYSLDTRGKFI--LSIAYSPDGKYLASGA 167

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT 349
            DG + +++   G    T   H   +  +T S + +  V++S DG ++ YD+       T
Sbjct: 168 IDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGT 227

Query: 350 LTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPT 409
           L+  +    +         F ++       + VW +     +     H+  V  + ++  
Sbjct: 228 LSGHASWVLNVAFCPDDTHFVSSSSDK--SVKVWDVGTRTCVHTFFDHQDQVWGVKYNG- 284

Query: 410 LTSTRLASASWDGTVRLWDC 429
              +++ S   D  + ++DC
Sbjct: 285 -NGSKIVSVGDDQEIHIYDC 303



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 48/190 (25%), Positives = 82/190 (43%), Gaps = 12/190 (6%)

Query: 302 GFCFVTFHEHKATVSGVTCSANKK----FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV- 356
           G  F     H   +  V    NKK      V+ SLD  V+ +   ++R+ R     SL  
Sbjct: 6   GILFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVW---KWRDERLDLQWSLEG 62

Query: 357 -QFSCVALDSSGEFCAAGGQDV-FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR 414
            Q   V++D S     A    +   I +W ++ GK ++ +        +LAFSP   S  
Sbjct: 63  HQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPD--SQY 120

Query: 415 LASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTC 474
           LA+ +  G V ++     + +          L +A+ PDG+ +A   +DG I  F+ +T 
Sbjct: 121 LATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATG 180

Query: 475 EQTGSVEGRS 484
           +   ++EG +
Sbjct: 181 KLLHTLEGHA 190


>AF100786-1|AAP97225.1|  305|Homo sapiens G protein beta
           subunit-like protein protein.
          Length = 305

 Score = 73.3 bits (172), Expect = 3e-12
 Identities = 59/276 (21%), Positives = 119/276 (43%), Gaps = 15/276 (5%)

Query: 195 KEN-KLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNI-GQL 252
           KEN + +VTG    L  + +  D  L    S+  H++  +SV         A  ++   +
Sbjct: 29  KENSETVVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHI 88

Query: 253 LVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHK 312
            +W+ ++ + +       +D   LA+SPD  ++ TG   GKV ++   +G    +     
Sbjct: 89  RLWDLENGKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRG 148

Query: 313 ATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAA 372
             +  +  S + K+  S ++DG +  +D+   +   TL   ++     +      +    
Sbjct: 149 KFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAM-PIRSLTFSPDSQLLVT 207

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD---- 428
              D + I ++ ++   L   L GH + V ++AF P    T   S+S D +V++WD    
Sbjct: 208 ASDDGY-IKIYDVQHANLAGTLSGHASWVLNVAFCP--DDTHFVSSSSDKSVKVWDVGTR 264

Query: 429 -CI----DREVQCEPIRLNSDALQVAFRPDGEEIAV 459
            C+    D + Q   ++ N +  ++    D +EI +
Sbjct: 265 TCVHTFFDHQDQVWGVKYNGNGSKIVSVGDDQEIHI 300



 Score = 69.7 bits (163), Expect = 3e-11
 Identities = 41/153 (26%), Positives = 69/153 (45%), Gaps = 1/153 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           + ++ Y  + K L +G   G+  + ++    L+HTL      I S++ SP    +  A  
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           + G + +++ Q         GH+  +  +A+ PD  H V+   D  VKVW+     C  T
Sbjct: 211 D-GYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWDVGTRTCVHT 269

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
           F +H+  V GV  + N    VS   D  +  YD
Sbjct: 270 FFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302



 Score = 57.2 bits (132), Expect = 2e-07
 Identities = 38/200 (19%), Positives = 90/200 (45%), Gaps = 9/200 (4%)

Query: 232 SISVSPPGDWIAFACPNIGQLLVWEWQS--EQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           +++ SP   ++A    ++G++ ++  +S  ++Y +  +G  +    +AYSPDG ++ +G 
Sbjct: 111 TLAFSPDSQYLATGT-HVGKVNIFGVESGKKEYSLDTRGKFI--LSIAYSPDGKYLASGA 167

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT 349
            DG + +++   G    T   H   +  +T S + +  V++S DG ++ YD+       T
Sbjct: 168 IDGIINIFDIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANLAGT 227

Query: 350 LTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPT 409
           L+  +    +         F ++       + VW +     +     H+  V  + ++  
Sbjct: 228 LSGHASWVLNVAFCPDDTHFVSSSSDK--SVKVWDVGTRTCVHTFFDHQDQVWGVKYNG- 284

Query: 410 LTSTRLASASWDGTVRLWDC 429
              +++ S   D  + ++DC
Sbjct: 285 -NGSKIVSVGDDQEIHIYDC 303



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 48/190 (25%), Positives = 82/190 (43%), Gaps = 12/190 (6%)

Query: 302 GFCFVTFHEHKATVSGVTCSANKK----FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV- 356
           G  F     H   +  V    NKK      V+ SLD  V+ +   ++R+ R     SL  
Sbjct: 6   GILFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVW---KWRDERLDLQWSLEG 62

Query: 357 -QFSCVALDSSGEFCAAGGQDV-FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR 414
            Q   V++D S     A    +   I +W ++ GK ++ +        +LAFSP   S  
Sbjct: 63  HQLGVVSVDISHTLPIAASSSLDAHIRLWDLENGKQIKSIDAGPVDAWTLAFSPD--SQY 120

Query: 415 LASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTC 474
           LA+ +  G V ++     + +          L +A+ PDG+ +A   +DG I  F+ +T 
Sbjct: 121 LATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATG 180

Query: 475 EQTGSVEGRS 484
           +   ++EG +
Sbjct: 181 KLLHTLEGHA 190


>AK222488-1|BAD96208.1|  317|Homo sapiens guanine nucleotide binding
           protein (G protein), beta polypeptide 2-like 1 varia
           protein.
          Length = 317

 Score = 72.9 bits (171), Expect = 4e-12
 Identities = 56/205 (27%), Positives = 95/205 (46%), Gaps = 12/205 (5%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVT 287
           H +S + +S  G + A +    G L +W+  +     +  GH+ D+  +A+S D   +V+
Sbjct: 64  HFVSDVVISSDGQF-ALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVS 122

Query: 288 GGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK--FFVSSSLDGTVRCYDLTR 343
           G  D  +K+WNT  G C  T  +  H   VS V  S N      VS   D  V+ ++L  
Sbjct: 123 GSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLAN 181

Query: 344 YRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSS 403
            +  +T         + V +   G  CA+GG+D  +  +W    GK L  L G +  +++
Sbjct: 182 CK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLWDFNEGKHLYTLDGGDI-INA 238

Query: 404 LAFSPTLTSTRLASASWDGTVRLWD 428
           L FSP   +     A+   ++++WD
Sbjct: 239 LCFSP---NRYWLCAATGPSIKIWD 260



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 5/164 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  ++ +  S DG   ++G +DG +++W+ T G     F  H   V  V  S++ + 
Sbjct: 60  RGHSHFVSDVVISSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQ 119

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDVFEIFVWS 384
            VS S D T++ ++      +           SCV    +SS     + G D   + VW+
Sbjct: 120 IVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKL-VKVWN 178

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           +   KL     GH   ++++  SP    +  AS   DG   LWD
Sbjct: 179 LANCKLKTNHIGHTGYLNTVTVSP--DGSLCASGGKDGQAMLWD 220



 Score = 56.4 bits (130), Expect = 3e-07
 Identities = 53/211 (25%), Positives = 88/211 (41%), Gaps = 9/211 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVV-TGGFDGKVKVWNTTN-----GFCFVTFHEHKATVSGVTC 320
           +GH+  +T +A +P    ++ +   D  + +W  T      G        H   VS V  
Sbjct: 12  KGHNGWVTQIATTPQFPDMILSASRDKTIIMWKLTRDETNYGIPQRALRGHSHFVSDVVI 71

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           S++ +F +S S DGT+R +DLT     R     +    S VA  S      +G +D   I
Sbjct: 72  SSDGQFALSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLS-VAFSSDNRQIVSGSRDK-TI 129

Query: 381 FVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
            +W+ +   K       H   VS + FSP  ++  + S  WD  V++W+  + +++   I
Sbjct: 130 KLWNTLGVCKYTVQDESHSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHI 189

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
                   V   PDG   A    DG    ++
Sbjct: 190 GHTGYLNTVTVSPDGSLCASGGKDGQAMLWD 220



 Score = 37.5 bits (83), Expect = 0.17
 Identities = 32/122 (26%), Positives = 52/122 (42%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L +  +   ++TL   +  I+++  SP   W+  A  
Sbjct: 195 LNTVTVSPDGSLCASGGKDGQAMLWDFNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 253

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 254 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 313

Query: 301 NG 302
            G
Sbjct: 314 IG 315


>BC015887-1|AAH15887.1|  404|Homo sapiens WD repeat and SOCS
           box-containing 2 protein.
          Length = 404

 Score = 72.1 bits (169), Expect = 7e-12
 Identities = 43/148 (29%), Positives = 74/148 (50%), Gaps = 6/148 (4%)

Query: 283 LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCS-ANKKFFVSSSLDGTVRCYDL 341
           L + TG  DG++K+W    G   +    H+  V  ++ + +     VS+S D T+R +DL
Sbjct: 124 LVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL 183

Query: 342 TRY-RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAP 400
            ++ +  + L+      + C         C+A G+    +F+WS++   L+  L GH++ 
Sbjct: 184 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEK--SVFLWSMRSYTLIRKLEGHQSS 241

Query: 401 VSSLAFSPTLTSTRLASASWDGTVRLWD 428
           V S  FSP   S  L +AS+D  V +WD
Sbjct: 242 VVSCDFSP--DSALLVTASYDTNVIMWD 267



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 53/237 (22%), Positives = 95/237 (40%), Gaps = 22/237 (9%)

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG-LHVVTGGFDGKVKVWN-TTNGFCF 305
           N GQ+ +WE Q+   ++   GH   +  L+++P G L +V+   D  +++W+   +G   
Sbjct: 131 NDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQI 190

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
                H   V   + S +     S++ + +V  + +  Y   R L        SC     
Sbjct: 191 QVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPD 250

Query: 366 SGEFCAAGGQDVFEIFVWSIKFGKLLEVL------------GGHEAPVSSLAFSPTLTST 413
           S     A       + +W    G+ L  L              H + + S+ FSP     
Sbjct: 251 SALLVTASYDT--NVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSP--EGL 306

Query: 414 RLASASWDGTVRLWDC-IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
            LA+ + D  +R+W   +   +   P+   ++ L   F P G  IA  T DG++ F+
Sbjct: 307 YLATVADDRLLRIWALELKTPIAFAPM---TNGLCCTFFPHGGVIATGTRDGHVQFW 360



 Score = 41.9 bits (94), Expect = 0.008
 Identities = 32/153 (20%), Positives = 62/153 (40%), Gaps = 1/153 (0%)

Query: 199 LLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQ 258
           +L TG + G   + E+    L+  LS  +  +  +S +P G  I  +      L +W+  
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184

Query: 259 SE-QYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSG 317
              + +    GH   + C + SPD   + +   +  V +W+  +         H+++V  
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244

Query: 318 VTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTL 350
              S +    V++S D  V  +D       R+L
Sbjct: 245 CDFSPDSALLVTASYDTNVIMWDPYTGERLRSL 277


>BC007417-1|AAH07417.2|  396|Homo sapiens WDR51A protein protein.
          Length = 396

 Score = 72.1 bits (169), Expect = 7e-12
 Identities = 52/220 (23%), Positives = 96/220 (43%), Gaps = 6/220 (2%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           L+VW  + +    +  GH   +TC+ +SP G  + +G  D  V++W          F  H
Sbjct: 32  LMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAH 91

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
            ATV  V   ++ + FV++S D TV+ +  T  + F    S  +    C      G    
Sbjct: 92  TATVRSVHFCSDGQSFVTASDDKTVKVW-ATHRQKFLFSLSQHINWVRCAKFSPDGRLIV 150

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCID 431
           +   D   + +W     + +     H   V+ + F P  + T +A+A  D TV++WD   
Sbjct: 151 SASDDK-TVKLWDKSSRECVHSYCEHGGFVTYVDFHP--SGTCIAAAGMDNTVKVWDVRT 207

Query: 432 REVQCEPIRLNSDALQ-VAFRPDGEEIAVSTLDGNITFFE 470
             +  +  +L+S A+  ++F P G  +  ++ D  +   +
Sbjct: 208 HRL-LQHYQLHSAAVNGLSFHPSGNYLITASSDSTLKILD 246



 Score = 68.9 bits (161), Expect = 6e-11
 Identities = 59/251 (23%), Positives = 108/251 (43%), Gaps = 7/251 (2%)

Query: 178 AIRNADRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSP 237
           A R    K  +T V +     LL +G       +  +P+V    T+    H  +  SV  
Sbjct: 43  AYRFTGHKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTV-FRAHTATVRSVHF 100

Query: 238 PGDWIAFACPNIGQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKV 296
             D  +F   +  + + VW    ++++     H   + C  +SPDG  +V+   D  VK+
Sbjct: 101 CSDGQSFVTASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKL 160

Query: 297 WNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV 356
           W+ ++  C  ++ EH   V+ V    +     ++ +D TV+ +D+  +R  +     S  
Sbjct: 161 WDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHS-A 219

Query: 357 QFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLA 416
             + ++   SG +      D   + +  +  G+LL  L GH+ P +++AFS   T    A
Sbjct: 220 AVNGLSFHPSGNYLITASSD-STLKILDLMEGRLLYTLHGHQGPATTVAFS--RTGEYFA 276

Query: 417 SASWDGTVRLW 427
           S   D  V +W
Sbjct: 277 SGGSDEQVMVW 287



 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 55/207 (26%), Positives = 80/207 (38%), Gaps = 4/207 (1%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +TC+ +S +   + +G  D  + VW+         F  HK  V+ V  S +   
Sbjct: 5   KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 64

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIK 386
             S S D TVR + +   +   T+          V   S G+       D   + VW+  
Sbjct: 65  LASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK-TVKVWATH 122

Query: 387 FGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL 446
             K L  L  H   V    FSP      + SAS D TV+LWD   RE             
Sbjct: 123 RQKFLFSLSQHINWVRCAKFSP--DGRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVT 180

Query: 447 QVAFRPDGEEIAVSTLDGNITFFEPST 473
            V F P G  IA + +D  +  ++  T
Sbjct: 181 YVDFHPSGTCIAAAGMDNTVKVWDVRT 207



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 61/296 (20%), Positives = 118/296 (39%), Gaps = 20/296 (6%)

Query: 17  KRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF 76
           +R FK   D VTC+D+S  ++ LA GS D+   +  ++       Y  +GH D +  V F
Sbjct: 1   ERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMK--PQSRAYRFTGHKDAVTCVNF 58

Query: 77  ERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIE 136
                 L + SR+  + +W  ++   E  V +  T+  + V   ++G   + F    D +
Sbjct: 59  SPSGHLLASGSRDKTVRIWVPNVKG-ESTVFRAHTATVRSVHFCSDG---QSFVTASDDK 114

Query: 137 KEKEYDSDR-----DAEQEQNNSKVNSEENDKRLMYK-------KLGRHYIGDAIRN-AD 183
             K + + R        Q  N  +      D RL+         KL      + + +  +
Sbjct: 115 TVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYCE 174

Query: 184 RKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIA 243
               +T V +H     +          + ++    L+    +    ++ +S  P G+++ 
Sbjct: 175 HGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYLI 234

Query: 244 FACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNT 299
            A  +   L + +    + +    GH    T +A+S  G +  +GG D +V VW +
Sbjct: 235 TASSD-STLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 289


>AF229181-1|AAF71302.1|  404|Homo sapiens CS box-containing WD
           protein protein.
          Length = 404

 Score = 72.1 bits (169), Expect = 7e-12
 Identities = 43/148 (29%), Positives = 74/148 (50%), Gaps = 6/148 (4%)

Query: 283 LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCS-ANKKFFVSSSLDGTVRCYDL 341
           L + TG  DG++K+W    G   +    H+  V  ++ + +     VS+S D T+R +DL
Sbjct: 124 LVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL 183

Query: 342 TRY-RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAP 400
            ++ +  + L+      + C         C+A G+    +F+WS++   L+  L GH++ 
Sbjct: 184 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEK--SVFLWSMRSYTLIRKLEGHQSS 241

Query: 401 VSSLAFSPTLTSTRLASASWDGTVRLWD 428
           V S  FSP   S  L +AS+D  V +WD
Sbjct: 242 VVSCDFSP--DSALLVTASYDTNVIMWD 267



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 53/237 (22%), Positives = 95/237 (40%), Gaps = 22/237 (9%)

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG-LHVVTGGFDGKVKVWN-TTNGFCF 305
           N GQ+ +WE Q+   ++   GH   +  L+++P G L +V+   D  +++W+   +G   
Sbjct: 131 NDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQI 190

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
                H   V   + S +     S++ + +V  + +  Y   R L        SC     
Sbjct: 191 QVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPD 250

Query: 366 SGEFCAAGGQDVFEIFVWSIKFGKLLEVL------------GGHEAPVSSLAFSPTLTST 413
           S     A       + +W    G+ L  L              H + + S+ FSP     
Sbjct: 251 SALLVTASYDT--NVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSP--EGL 306

Query: 414 RLASASWDGTVRLWDC-IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
            LA+ + D  +R+W   +   +   P+   ++ L   F P G  IA  T DG++ F+
Sbjct: 307 YLATVADDRLLRIWALELKTPIAFAPM---TNGLCCTFFPHGGVIATGTRDGHVQFW 360



 Score = 41.9 bits (94), Expect = 0.008
 Identities = 32/153 (20%), Positives = 62/153 (40%), Gaps = 1/153 (0%)

Query: 199 LLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQ 258
           +L TG + G   + E+    L+  LS  +  +  +S +P G  I  +      L +W+  
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184

Query: 259 SE-QYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSG 317
              + +    GH   + C + SPD   + +   +  V +W+  +         H+++V  
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244

Query: 318 VTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTL 350
              S +    V++S D  V  +D       R+L
Sbjct: 245 CDFSPDSALLVTASYDTNVIMWDPYTGERLRSL 277


>AF163324-1|AAF80478.1|  404|Homo sapiens WSB-2 protein.
          Length = 404

 Score = 72.1 bits (169), Expect = 7e-12
 Identities = 43/148 (29%), Positives = 74/148 (50%), Gaps = 6/148 (4%)

Query: 283 LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCS-ANKKFFVSSSLDGTVRCYDL 341
           L + TG  DG++K+W    G   +    H+  V  ++ + +     VS+S D T+R +DL
Sbjct: 124 LVLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDL 183

Query: 342 TRY-RNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAP 400
            ++ +  + L+      + C         C+A G+    +F+WS++   L+  L GH++ 
Sbjct: 184 NKHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEK--SVFLWSMRSYTLIRKLEGHQSS 241

Query: 401 VSSLAFSPTLTSTRLASASWDGTVRLWD 428
           V S  FSP   S  L +AS+D  V +WD
Sbjct: 242 VVSCDFSP--DSALLVTASYDTNVIMWD 267



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 53/237 (22%), Positives = 95/237 (40%), Gaps = 22/237 (9%)

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG-LHVVTGGFDGKVKVWN-TTNGFCF 305
           N GQ+ +WE Q+   ++   GH   +  L+++P G L +V+   D  +++W+   +G   
Sbjct: 131 NDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLNKHGKQI 190

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
                H   V   + S +     S++ + +V  + +  Y   R L        SC     
Sbjct: 191 QVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVSCDFSPD 250

Query: 366 SGEFCAAGGQDVFEIFVWSIKFGKLLEVL------------GGHEAPVSSLAFSPTLTST 413
           S     A       + +W    G+ L  L              H + + S+ FSP     
Sbjct: 251 SALLVTASYDT--NVIMWDPYTGERLRSLHHTQVDPAMDDSDVHISSLRSVCFSP--EGL 306

Query: 414 RLASASWDGTVRLWDC-IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
            LA+ + D  +R+W   +   +   P+   ++ L   F P G  IA  T DG++ F+
Sbjct: 307 YLATVADDRLLRIWALELKTPIAFAPM---TNGLCCTFFPHGGVIATGTRDGHVQFW 360



 Score = 41.9 bits (94), Expect = 0.008
 Identities = 32/153 (20%), Positives = 62/153 (40%), Gaps = 1/153 (0%)

Query: 199 LLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQ 258
           +L TG + G   + E+    L+  LS  +  +  +S +P G  I  +      L +W+  
Sbjct: 125 VLATGLNDGQIKIWEVQTGLLLLNLSGHQDVVRDLSFTPSGSLILVSASRDKTLRIWDLN 184

Query: 259 SE-QYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSG 317
              + +    GH   + C + SPD   + +   +  V +W+  +         H+++V  
Sbjct: 185 KHGKQIQVLSGHLQWVYCCSISPDCSMLCSAAGEKSVFLWSMRSYTLIRKLEGHQSSVVS 244

Query: 318 VTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTL 350
              S +    V++S D  V  +D       R+L
Sbjct: 245 CDFSPDSALLVTASYDTNVIMWDPYTGERLRSL 277


>EF011619-1|ABK41109.1|  478|Homo sapiens CDW9/WDR51B protein.
          Length = 478

 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 59/260 (22%), Positives = 103/260 (39%), Gaps = 5/260 (1%)

Query: 178 AIRNADRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSP 237
           A R    K  +T+VQ+     LL +        L                  + S+  S 
Sbjct: 53  AYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSA 112

Query: 238 PGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
            G ++A A  +   + VW    ++++     H+  + C  +SPDG  +V+   D  +K+W
Sbjct: 113 DGQFLATASED-KSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171

Query: 298 NTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQ 357
           +TTN  C   F +     + V  + +     S+  D TV+ +D+ R              
Sbjct: 172 DTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDV-RVNKLLQHYQVHSGG 230

Query: 358 FSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLAS 417
            +C++   SG +      D   + +  +  G+L+  L GH  PV +++FS        AS
Sbjct: 231 VNCISFHPSGNYLITASSD-GTLKILDLLEGRLIYTLQGHTGPVFTVSFSK--GGELFAS 287

Query: 418 ASWDGTVRLWDCIDREVQCE 437
              D  V LW     E+ C+
Sbjct: 288 GGADTQVLLWRTNFDELHCK 307



 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 54/242 (22%), Positives = 108/242 (44%), Gaps = 7/242 (2%)

Query: 230 ISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           I+S+ +SP G  +A A  +   L++W ++      +  GH   +T + +SP G  + +  
Sbjct: 21  ITSLDLSPNGKQLATASWDTF-LMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASAS 79

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT 349
            D  V++W       F  F  H A V  V  SA+ +F  ++S D +++ + + R R   +
Sbjct: 80  RDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYS 139

Query: 350 LTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPT 409
           L   +     C      G    +  +D   I +W     + +          + + F+P 
Sbjct: 140 LYRHT-HWVRCAKFSPDGRLIVSCSEDK-TIKIWDTTNKQCVNNFSDSVGFANFVDFNP- 196

Query: 410 LTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQ-VAFRPDGEEIAVSTLDGNITF 468
            + T +ASA  D TV++WD    ++  +  +++S  +  ++F P G  +  ++ DG +  
Sbjct: 197 -SGTCIASAGSDQTVKVWDVRVNKL-LQHYQVHSGGVNCISFHPSGNYLITASSDGTLKI 254

Query: 469 FE 470
            +
Sbjct: 255 LD 256



 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 58/211 (27%), Positives = 92/211 (43%), Gaps = 18/211 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +T L  SP+G  + T  +D  + +WN         +  HK  V+ V  S +   
Sbjct: 15  KGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNL 74

Query: 327 FVSSSLDGTVRCY---DLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVW 383
             S+S D TVR +      ++  F+  T+P       V   + G+F A   +D   I VW
Sbjct: 75  LASASRDRTVRLWIPDKRGKFSEFKAHTAP----VRSVDFSADGQFLATASEDK-SIKVW 129

Query: 384 SIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNS 443
           S+   + L  L  H   V    FSP      + S S D T+++WD  ++  QC  +   S
Sbjct: 130 SMYRQRFLYSLYRHTHWVRCAKFSP--DGRLIVSCSEDKTIKIWDTTNK--QC--VNNFS 183

Query: 444 DALQVA----FRPDGEEIAVSTLDGNITFFE 470
           D++  A    F P G  IA +  D  +  ++
Sbjct: 184 DSVGFANFVDFNPSGTCIASAGSDQTVKVWD 214



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 4/113 (3%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C+ +      L   S D T KI  ++ LE   +Y+L GHT  +  V F +      + 
Sbjct: 231 VNCISFHPSGNYLITASSDGTLKI--LDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 288

Query: 87  SRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEK 139
             + Q+ LW  +   DEL  K       KR+   +  +L + +       +EK
Sbjct: 289 GADTQVLLWRTNF--DELHCKGLTKRNLKRLHFDSPPHLLDIYPRTPHPHEEK 339



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 15 IMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGV 74
          +++R FK     +T LD S   + LA  S DT   +    +  +   Y   GH D +  V
Sbjct: 9  VLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWN--FKPHARAYRYVGHKDVVTSV 66

Query: 75 FFERKSLDLITVSRNGQLCLW 95
           F      L + SR+  + LW
Sbjct: 67 QFSPHGNLLASASRDRTVRLW 87


>BC026080-1|AAH26080.1|  478|Homo sapiens WD repeat domain 51B
           protein.
          Length = 478

 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 59/260 (22%), Positives = 103/260 (39%), Gaps = 5/260 (1%)

Query: 178 AIRNADRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSP 237
           A R    K  +T+VQ+     LL +        L                  + S+  S 
Sbjct: 53  AYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSA 112

Query: 238 PGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
            G ++A A  +   + VW    ++++     H+  + C  +SPDG  +V+   D  +K+W
Sbjct: 113 DGQFLATASED-KSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171

Query: 298 NTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQ 357
           +TTN  C   F +     + V  + +     S+  D TV+ +D+ R              
Sbjct: 172 DTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDV-RVNKLLQHYQVHSGG 230

Query: 358 FSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLAS 417
            +C++   SG +      D   + +  +  G+L+  L GH  PV +++FS        AS
Sbjct: 231 VNCISFHPSGNYLITASSD-GTLKILDLLEGRLIYTLQGHTGPVFTVSFSK--GGELFAS 287

Query: 418 ASWDGTVRLWDCIDREVQCE 437
              D  V LW     E+ C+
Sbjct: 288 GGADTQVLLWRTNFDELHCK 307



 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 54/242 (22%), Positives = 108/242 (44%), Gaps = 7/242 (2%)

Query: 230 ISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           I+S+ +SP G  +A A  +   L++W ++      +  GH   +T + +SP G  + +  
Sbjct: 21  ITSLDLSPNGKQLATASWDTF-LMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASAS 79

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT 349
            D  V++W       F  F  H A V  V  SA+ +F  ++S D +++ + + R R   +
Sbjct: 80  RDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYS 139

Query: 350 LTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPT 409
           L   +     C      G    +  +D   I +W     + +          + + F+P 
Sbjct: 140 LYRHT-HWVRCAKFSPDGRLIVSCSEDK-TIKIWDTTNKQCVNNFSDSVGFANFVDFNP- 196

Query: 410 LTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQ-VAFRPDGEEIAVSTLDGNITF 468
            + T +ASA  D TV++WD    ++  +  +++S  +  ++F P G  +  ++ DG +  
Sbjct: 197 -SGTCIASAGSDQTVKVWDVRVNKL-LQHYQVHSGGVNCISFHPSGNYLITASSDGTLKI 254

Query: 469 FE 470
            +
Sbjct: 255 LD 256



 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 58/211 (27%), Positives = 92/211 (43%), Gaps = 18/211 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +T L  SP+G  + T  +D  + +WN         +  HK  V+ V  S +   
Sbjct: 15  KGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNL 74

Query: 327 FVSSSLDGTVRCY---DLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVW 383
             S+S D TVR +      ++  F+  T+P       V   + G+F A   +D   I VW
Sbjct: 75  LASASRDRTVRLWIPDKRGKFSEFKAHTAP----VRSVDFSADGQFLATASEDK-SIKVW 129

Query: 384 SIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNS 443
           S+   + L  L  H   V    FSP      + S S D T+++WD  ++  QC  +   S
Sbjct: 130 SMYRQRFLYSLYRHTHWVRCAKFSP--DGRLIVSCSEDKTIKIWDTTNK--QC--VNNFS 183

Query: 444 DALQVA----FRPDGEEIAVSTLDGNITFFE 470
           D++  A    F P G  IA +  D  +  ++
Sbjct: 184 DSVGFANFVDFNPSGTCIASAGSDQTVKVWD 214



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 4/113 (3%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C+ +      L   S D T KI  ++ LE   +Y+L GHT  +  V F +      + 
Sbjct: 231 VNCISFHPSGNYLITASSDGTLKI--LDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 288

Query: 87  SRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEK 139
             + Q+ LW  +   DEL  K       KR+   +  +L + +       +EK
Sbjct: 289 GADTQVLLWRTNF--DELHCKGLTKRNLKRLHFDSPPHLLDIYPRTPHPHEEK 339



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 15 IMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGV 74
          +++R FK     +T LD S   + LA  S DT   +    +  +   Y   GH D +  V
Sbjct: 9  VLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWN--FKPHARAYRYVGHKDVVTSV 66

Query: 75 FFERKSLDLITVSRNGQLCLW 95
           F      L + SR+  + LW
Sbjct: 67 QFSPHGNLLASASRDRTVRLW 87


>AK074772-1|BAC11198.1|  478|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90291 fis, clone NT2RP1001031, weakly similar to
           VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
          Length = 478

 Score = 71.7 bits (168), Expect = 9e-12
 Identities = 59/260 (22%), Positives = 103/260 (39%), Gaps = 5/260 (1%)

Query: 178 AIRNADRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSP 237
           A R    K  +T+VQ+     LL +        L                  + S+  S 
Sbjct: 53  AYRYVGHKDVVTSVQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSA 112

Query: 238 PGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
            G ++A A  +   + VW    ++++     H+  + C  +SPDG  +V+   D  +K+W
Sbjct: 113 DGQFLATASED-KSIKVWSMYRQRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIW 171

Query: 298 NTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQ 357
           +TTN  C   F +     + V  + +     S+  D TV+ +D+ R              
Sbjct: 172 DTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDV-RVNKLLQHYQVHSGG 230

Query: 358 FSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLAS 417
            +C++   SG +      D   + +  +  G+L+  L GH  PV +++FS        AS
Sbjct: 231 VNCISFHPSGNYLITASSD-GTLKILDLLEGRLIYTLQGHTGPVFTVSFSK--GGELFAS 287

Query: 418 ASWDGTVRLWDCIDREVQCE 437
              D  V LW     E+ C+
Sbjct: 288 GGADTQVLLWRTNFDELHCK 307



 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 54/242 (22%), Positives = 108/242 (44%), Gaps = 7/242 (2%)

Query: 230 ISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           I+S+ +SP G  +A A  +   L++W ++      +  GH   +T + +SP G  + +  
Sbjct: 21  ITSLDLSPNGKQLATASWDTF-LMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNLLASAS 79

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT 349
            D  V++W       F  F  H A V  V  SA+ +F  ++S D +++ + + R R   +
Sbjct: 80  RDRTVRLWIPDKRGKFSEFKAHTAPVRSVDFSADGQFLATASEDKSIKVWSMYRQRFLYS 139

Query: 350 LTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPT 409
           L   +     C      G    +  +D   I +W     + +          + + F+P 
Sbjct: 140 LYRHT-HWVRCAKFSPDGRLIVSCSEDK-TIKIWDTTNKQCVNNFSDSVGFANFVDFNP- 196

Query: 410 LTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQ-VAFRPDGEEIAVSTLDGNITF 468
            + T +ASA  D TV++WD    ++  +  +++S  +  ++F P G  +  ++ DG +  
Sbjct: 197 -SGTCIASAGSDQTVKVWDVRVNKL-LQHYQVHSGGVNCISFHPSGNYLITASSDGTLKI 254

Query: 469 FE 470
            +
Sbjct: 255 LD 256



 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 58/211 (27%), Positives = 92/211 (43%), Gaps = 18/211 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +T L  SP+G  + T  +D  + +WN         +  HK  V+ V  S +   
Sbjct: 15  KGHKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTSVQFSPHGNL 74

Query: 327 FVSSSLDGTVRCY---DLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVW 383
             S+S D TVR +      ++  F+  T+P       V   + G+F A   +D   I VW
Sbjct: 75  LASASRDRTVRLWIPDKRGKFSEFKAHTAP----VRSVDFSADGQFLATASEDK-SIKVW 129

Query: 384 SIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNS 443
           S+   + L  L  H   V    FSP      + S S D T+++WD  ++  QC  +   S
Sbjct: 130 SMYRQRFLYSLYRHTHWVRCAKFSP--DGRLIVSCSEDKTIKIWDTTNK--QC--VNNFS 183

Query: 444 DALQVA----FRPDGEEIAVSTLDGNITFFE 470
           D++  A    F P G  IA +  D  +  ++
Sbjct: 184 DSVGFANFVDFNPSGTCIASAGSDQTVKVWD 214



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 4/113 (3%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C+ +      L   S D T KI  ++ LE   +Y+L GHT  +  V F +      + 
Sbjct: 231 VNCISFHPSGNYLITASSDGTLKI--LDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 288

Query: 87  SRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEK 139
             + Q+ LW  +   DEL  K       KR+   +  +L + +       +EK
Sbjct: 289 GADTQVLLWRTNF--DELHCKGLTKRNLKRLHFDSPPHLLDIYPRTPHPHEEK 339



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 2/81 (2%)

Query: 15 IMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGV 74
          +++R FK     +T LD S   + LA  S DT   +    +  +   Y   GH D +  V
Sbjct: 9  VLERYFKGHKAAITSLDLSPNGKQLATASWDTFLMLWN--FKPHARAYRYVGHKDVVTSV 66

Query: 75 FFERKSLDLITVSRNGQLCLW 95
           F      L + SR+  + LW
Sbjct: 67 QFSPHGNLLASASRDRTVRLW 87


>AK075289-1|BAC11525.1|  407|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90808 fis, clone Y79AA1000777, weakly similar to
           VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
          Length = 407

 Score = 71.3 bits (167), Expect = 1e-11
 Identities = 70/300 (23%), Positives = 125/300 (41%), Gaps = 13/300 (4%)

Query: 133 DDIEKEKEYDSDRDA----EQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKL 188
           +D   E+ +   RDA    +   N  ++ S   D  LM   +       A R    K  +
Sbjct: 7   EDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQ--SRAYRFTGHKDAV 64

Query: 189 TAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPN 248
           T V +     LL +G       +  +P+V    T+    H  +  SV    D  +F   +
Sbjct: 65  TCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTV-FRAHTATVRSVHFCSDGQSFVTAS 122

Query: 249 IGQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
             + + VW    ++++     H   + C  +SPDG  +V+   D  VK+W+ ++  C  +
Sbjct: 123 DDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 182

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSG 367
           + EH   V+ V    +     ++ +D TV+ +D+  YR  +     S    + ++   SG
Sbjct: 183 YCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQHYQLHS-AAVNGLSFHPSG 241

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
            +      D   + +  +  G+LL  L GH+ P +++AFS   T    AS   D  V +W
Sbjct: 242 NYLITASSD-STLKILDLMEGRLLYTLHGHQGPATTVAFS--RTGEYFASGGSDEQVMVW 298



 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 55/207 (26%), Positives = 80/207 (38%), Gaps = 4/207 (1%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +TC+ +S +   + +G  D  + VW+         F  HK  V+ V  S +   
Sbjct: 16  KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 75

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIK 386
             S S D TVR + +   +   T+          V   S G+       D   + VW+  
Sbjct: 76  LASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK-TVKVWATH 133

Query: 387 FGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL 446
             K L  L  H   V    FSP      + SAS D TV+LWD   RE             
Sbjct: 134 RQKFLFSLSQHINWVRCAKFSPD--GRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVT 191

Query: 447 QVAFRPDGEEIAVSTLDGNITFFEPST 473
            V F P G  IA + +D  +  ++  T
Sbjct: 192 YVDFHPSGTCIAAAGMDNTVKVWDVRT 218



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 61/297 (20%), Positives = 119/297 (40%), Gaps = 20/297 (6%)

Query: 16  MKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVF 75
           ++R FK   D VTC+D+S  ++ LA GS D+   +  ++       Y  +GH D +  V 
Sbjct: 11  LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMK--PQSRAYRFTGHKDAVTCVN 68

Query: 76  FERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDI 135
           F      L + SR+  + +W  ++   E  V +  T+  + V   ++G   + F    D 
Sbjct: 69  FSPSGHLLASGSRDKTVRIWVPNVKG-ESTVFRAHTATVRSVHFCSDG---QSFVTASDD 124

Query: 136 EKEKEYDSDR-----DAEQEQNNSKVNSEENDKRLMYK-------KLGRHYIGDAIRN-A 182
           +  K + + R        Q  N  +      D RL+         KL      + + +  
Sbjct: 125 KTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYC 184

Query: 183 DRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWI 242
           +    +T V +H     +          + ++    L+    +    ++ +S  P G+++
Sbjct: 185 EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTYRLLQHYQLHSAAVNGLSFHPSGNYL 244

Query: 243 AFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNT 299
             A  +   L + +    + +    GH    T +A+S  G +  +GG D +V VW +
Sbjct: 245 ITASSD-STLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300


>BC113421-1|AAI13422.1|  514|Homo sapiens transducin (beta)-like
           1X-linked receptor 1 protein.
          Length = 514

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 57/222 (25%), Positives = 95/222 (42%), Gaps = 12/222 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G  +++ G D    +W+   G     F  H A    V   +N  F  
Sbjct: 265 HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTF-A 323

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L + R  +T    +  + + +  D +G   A+   D+  + +WS+K  
Sbjct: 324 SCSTDMCIHVCKLGQDRPIKTFQGHTN-EVNAIKWDPTGNLLASCSDDM-TLKIWSMKQD 381

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT   T        LASAS+D TVRLWD +DR +    +  
Sbjct: 382 NCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD-VDRGICIHTLTK 440

Query: 442 NSDAL-QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
           + + +  VAF PDG  +A  + D  +  +   T     S  G
Sbjct: 441 HQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 31/130 (23%), Positives = 59/130 (45%), Gaps = 10/130 (7%)

Query: 220 IHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYS 279
           I T     + +++I   P G+ +A +C +   L +W  + +  V   Q H+ ++  + +S
Sbjct: 342 IKTFQGHTNEVNAIKWDPTGNLLA-SCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400

Query: 280 PDG---------LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSS 330
           P G         L + +  FD  V++W+   G C  T  +H+  V  V  S + ++  S 
Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 460

Query: 331 SLDGTVRCYD 340
           S D  V  ++
Sbjct: 461 SFDKCVHIWN 470



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 41/159 (25%), Positives = 76/159 (47%), Gaps = 12/159 (7%)

Query: 272 DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSS 331
           D+T L ++ +G  + TG +DG  ++W T +G    T  +HK  +  +  +    F +S+ 
Sbjct: 227 DVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILSAG 285

Query: 332 LDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           +D T   +D       + F   ++P+L     V   S+  F A+   D+  I V  +   
Sbjct: 286 VDKTTIIWDAHTGEAKQQFPFHSAPAL----DVDWQSNNTF-ASCSTDMC-IHVCKLGQD 339

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           + ++   GH   V+++ + P  T   LAS S D T+++W
Sbjct: 340 RPIKTFQGHTNEVNAIKWDP--TGNLLASCSDDMTLKIW 376



 Score = 42.7 bits (96), Expect = 0.005
 Identities = 38/167 (22%), Positives = 67/167 (40%), Gaps = 13/167 (7%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++ A+++     LL +        +  M   N +H L      I +I  SP G       
Sbjct: 351 EVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPN 410

Query: 247 PNI--------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN 298
            N+          + +W+      +     H   +  +A+SPDG ++ +G FD  V +WN
Sbjct: 411 ANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 470

Query: 299 TTNGFCFVTFHEHKAT--VSGVTCSANKKFFVSSSLDGTVRCYDLTR 343
           T  G      H ++ T  +  V  +A      +S+ DG+V   DL +
Sbjct: 471 TQTG---ALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 514



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           +VT LDW+S   LLA GS D   +I T +   N+   +L  H   I  + + +K   +++
Sbjct: 227 DVTSLDWNSEGTLLATGSYDGFARIWTKD--GNLAS-TLGQHKGPIFALKWNKKGNFILS 283

Query: 86  VSRNGQLCLWEA 97
              +    +W+A
Sbjct: 284 AGVDKTTIIWDA 295



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP 452
           VL GHE+ V   A++P   S  LAS S D T R+W+  +              L+   R 
Sbjct: 164 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWNLSENSTSGS----TQLVLRHCIRE 217

Query: 453 DGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
            G+++  +    ++ +    T   TGS +G
Sbjct: 218 GGQDVPSNKDVTSLDWNSEGTLLATGSYDG 247


>AK022956-1|BAB14331.1|  514|Homo sapiens protein ( Homo sapiens
           cDNA FLJ12894 fis, clone NT2RP2004170, moderately
           similar to Homo sapiens mRNA for transducin (beta) like
           1 protein. ).
          Length = 514

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 57/222 (25%), Positives = 95/222 (42%), Gaps = 12/222 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G  +++ G D    +W+   G     F  H A    V   +N  F  
Sbjct: 265 HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTF-A 323

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L + R  +T    +  + + +  D +G   A+   D+  + +WS+K  
Sbjct: 324 SCSTDMCIHVCKLGQDRPIKTFQGHTN-EVNAIKWDPTGNLLASCSDDM-TLKIWSMKQD 381

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT   T        LASAS+D TVRLWD +DR +    +  
Sbjct: 382 NCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD-VDRGICIHTLTK 440

Query: 442 NSDAL-QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
           + + +  VAF PDG  +A  + D  +  +   T     S  G
Sbjct: 441 HQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 31/130 (23%), Positives = 59/130 (45%), Gaps = 10/130 (7%)

Query: 220 IHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYS 279
           I T     + +++I   P G+ +A +C +   L +W  + +  V   Q H+ ++  + +S
Sbjct: 342 IKTFQGHTNEVNAIKWDPTGNLLA-SCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400

Query: 280 PDG---------LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSS 330
           P G         L + +  FD  V++W+   G C  T  +H+  V  V  S + ++  S 
Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 460

Query: 331 SLDGTVRCYD 340
           S D  V  ++
Sbjct: 461 SFDKCVHIWN 470



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 41/159 (25%), Positives = 76/159 (47%), Gaps = 12/159 (7%)

Query: 272 DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSS 331
           D+T L ++ +G  + TG +DG  ++W T +G    T  +HK  +  +  +    F +S+ 
Sbjct: 227 DVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILSAG 285

Query: 332 LDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           +D T   +D       + F   ++P+L     V   S+  F A+   D+  I V  +   
Sbjct: 286 VDKTTIIWDAHTGEAKQQFPFHSAPAL----DVDWQSNNTF-ASCSTDMC-IHVCKLGQD 339

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           + ++   GH   V+++ + P  T   LAS S D T+++W
Sbjct: 340 RPIKTFQGHTNEVNAIKWDP--TGNLLASCSDDMTLKIW 376



 Score = 42.7 bits (96), Expect = 0.005
 Identities = 38/167 (22%), Positives = 67/167 (40%), Gaps = 13/167 (7%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++ A+++     LL +        +  M   N +H L      I +I  SP G       
Sbjct: 351 EVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPN 410

Query: 247 PNI--------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN 298
            N+          + +W+      +     H   +  +A+SPDG ++ +G FD  V +WN
Sbjct: 411 ANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 470

Query: 299 TTNGFCFVTFHEHKAT--VSGVTCSANKKFFVSSSLDGTVRCYDLTR 343
           T  G      H ++ T  +  V  +A      +S+ DG+V   DL +
Sbjct: 471 TQTG---ALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 514



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           +VT LDW+S   LLA GS D   +I T +   N+   +L  H   I  + + +K   +++
Sbjct: 227 DVTSLDWNSEGTLLATGSYDGFARIWTKD--GNLAS-TLGQHKGPIFALKWNKKGNFILS 283

Query: 86  VSRNGQLCLWEA 97
              +    +W+A
Sbjct: 284 AGVDKTTIIWDA 295



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP 452
           VL GHE+ V   A++P   S  LAS S D T R+W+  +              L+   R 
Sbjct: 164 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWNLSENSTSGS----TQLVLRHCIRE 217

Query: 453 DGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
            G+++  +    ++ +    T   TGS +G
Sbjct: 218 GGQDVPSNKDVTSLDWNSEGTLLATGSYDG 247


>AF314544-1|AAK00301.1|  514|Homo sapiens nuclear receptor
           co-repressor/HDAC3 complex subunit TBLR1 protein.
          Length = 514

 Score = 70.9 bits (166), Expect = 2e-11
 Identities = 57/222 (25%), Positives = 95/222 (42%), Gaps = 12/222 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G  +++ G D    +W+   G     F  H A    V   +N  F  
Sbjct: 265 HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTF-A 323

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L + R  +T    +  + + +  D +G   A+   D+  + +WS+K  
Sbjct: 324 SCSTDMCIHVCKLGQDRPIKTFQGHTN-EVNAIKWDPTGNLLASCSDDM-TLKIWSMKQD 381

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT   T        LASAS+D TVRLWD +DR +    +  
Sbjct: 382 NCVHDLQAHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD-VDRGICIHTLTK 440

Query: 442 NSDAL-QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
           + + +  VAF PDG  +A  + D  +  +   T     S  G
Sbjct: 441 HQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 31/130 (23%), Positives = 59/130 (45%), Gaps = 10/130 (7%)

Query: 220 IHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYS 279
           I T     + +++I   P G+ +A +C +   L +W  + +  V   Q H+ ++  + +S
Sbjct: 342 IKTFQGHTNEVNAIKWDPTGNLLA-SCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWS 400

Query: 280 PDG---------LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSS 330
           P G         L + +  FD  V++W+   G C  T  +H+  V  V  S + ++  S 
Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 460

Query: 331 SLDGTVRCYD 340
           S D  V  ++
Sbjct: 461 SFDKCVHIWN 470



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 41/159 (25%), Positives = 76/159 (47%), Gaps = 12/159 (7%)

Query: 272 DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSS 331
           D+T L ++ +G  + TG +DG  ++W T +G    T  +HK  +  +  +    F +S+ 
Sbjct: 227 DVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILSAG 285

Query: 332 LDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           +D T   +D       + F   ++P+L     V   S+  F A+   D+  I V  +   
Sbjct: 286 VDKTTIIWDAHTGEAKQQFPFHSAPAL----DVDWQSNNTF-ASCSTDMC-IHVCKLGQD 339

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           + ++   GH   V+++ + P  T   LAS S D T+++W
Sbjct: 340 RPIKTFQGHTNEVNAIKWDP--TGNLLASCSDDMTLKIW 376



 Score = 42.7 bits (96), Expect = 0.005
 Identities = 38/167 (22%), Positives = 67/167 (40%), Gaps = 13/167 (7%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++ A+++     LL +        +  M   N +H L      I +I  SP G       
Sbjct: 351 EVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGPGTNNPN 410

Query: 247 PNI--------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN 298
            N+          + +W+      +     H   +  +A+SPDG ++ +G FD  V +WN
Sbjct: 411 ANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 470

Query: 299 TTNGFCFVTFHEHKAT--VSGVTCSANKKFFVSSSLDGTVRCYDLTR 343
           T  G      H ++ T  +  V  +A      +S+ DG+V   DL +
Sbjct: 471 TQTG---ALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 514



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           +VT LDW+S   LLA GS D   +I T +   N+   +L  H   I  + + +K   +++
Sbjct: 227 DVTSLDWNSEGTLLATGSYDGFARIWTKD--GNLAS-TLGQHKGPIFALKWNKKGNFILS 283

Query: 86  VSRNGQLCLWEA 97
              +    +W+A
Sbjct: 284 AGVDKTTIIWDA 295



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP 452
           VL GHE+ V   A++P   S  LAS S D T R+W+  +              L+   R 
Sbjct: 164 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWNLSENSTSGS----TQLVLRHCIRE 217

Query: 453 DGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
            G+++  +    ++ +    T   TGS +G
Sbjct: 218 GGQDVPSNKDVTSLDWNSEGTLLATGSYDG 247


>BC028628-1|AAH28628.1|  375|Homo sapiens WDR71 protein protein.
          Length = 375

 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 50/188 (26%), Positives = 84/188 (44%), Gaps = 8/188 (4%)

Query: 158 SEENDKRLMYKKLGRHYIG-DAIRNADRKVKLTAVQYHKEN-KLLVTGFSSGLFFLHEMP 215
           S +N K  +Y  L    IG D I         T  + +K++  +     ++   FL    
Sbjct: 9   SLQNRKPSLYGSLTCQGIGLDGIPEVTASEGFTVNEINKKSIHISCPKENASSKFLAPYT 68

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTC 275
             + IHT SI+      + +S  G  +  +    G + +W+  + +     +GH  D+ C
Sbjct: 69  TFSRIHTKSIT-----CLDISSRGG-LGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNC 122

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGT 335
             + P GL V++GG D ++K+W+  +  C VTF  HK  +         +  VS+S DGT
Sbjct: 123 CRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGT 182

Query: 336 VRCYDLTR 343
            R +D  R
Sbjct: 183 ARLWDCGR 190



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 5/126 (3%)

Query: 305 FVTFHE-HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           + TF   H  +++ +  S+     VSSS DGT++ +  +     R +    +   +C   
Sbjct: 67  YTTFSRIHTKSITCLDISSRGGLGVSSSTDGTMKIWQASN-GELRRVLEGHVFDVNCCRF 125

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
             SG    +GG D  ++ +WS +    +    GH+  +   A         + SAS DGT
Sbjct: 126 FPSGLVVLSGGMDA-QLKIWSAEDASCVVTFKGHKGGILDTAIVDR--GRNVVSASRDGT 182

Query: 424 VRLWDC 429
            RLWDC
Sbjct: 183 ARLWDC 188



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 17/72 (23%), Positives = 32/72 (44%)

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           QL +W  +    V+  +GH   +   A    G +VV+   DG  ++W+     C     +
Sbjct: 140 QLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSACLGVLAD 199

Query: 311 HKATVSGVTCSA 322
             ++++GV   A
Sbjct: 200 CGSSINGVAVGA 211


>AF087895-1|AAP97194.1|  375|Homo sapiens G-16 protein.
          Length = 375

 Score = 70.5 bits (165), Expect = 2e-11
 Identities = 50/188 (26%), Positives = 84/188 (44%), Gaps = 8/188 (4%)

Query: 158 SEENDKRLMYKKLGRHYIG-DAIRNADRKVKLTAVQYHKEN-KLLVTGFSSGLFFLHEMP 215
           S +N K  +Y  L    IG D I         T  + +K++  +     ++   FL    
Sbjct: 9   SLQNRKPSLYGSLTCQGIGLDGIPEVTASEGFTVNEINKKSIHISCPKENASSKFLAPYT 68

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTC 275
             + IHT SI+      + +S  G  +  +    G + +W+  + +     +GH  D+ C
Sbjct: 69  TFSRIHTKSIT-----CLDISSRGG-LGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNC 122

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGT 335
             + P GL V++GG D ++K+W+  +  C VTF  HK  +         +  VS+S DGT
Sbjct: 123 CRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGT 182

Query: 336 VRCYDLTR 343
            R +D  R
Sbjct: 183 ARLWDCGR 190



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 5/126 (3%)

Query: 305 FVTFHE-HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           + TF   H  +++ +  S+     VSSS DGT++ +  +     R +    +   +C   
Sbjct: 67  YTTFSRIHTKSITCLDISSRGGLGVSSSTDGTMKIWQASN-GELRRVLEGHVFDVNCCRF 125

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
             SG    +GG D  ++ +WS +    +    GH+  +   A         + SAS DGT
Sbjct: 126 FPSGLVVLSGGMDA-QLKIWSAEDASCVVTFKGHKGGILDTAIVDR--GRNVVSASRDGT 182

Query: 424 VRLWDC 429
            RLWDC
Sbjct: 183 ARLWDC 188



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 17/72 (23%), Positives = 32/72 (44%)

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           QL +W  +    V+  +GH   +   A    G +VV+   DG  ++W+     C     +
Sbjct: 140 QLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSGCLGVLAD 199

Query: 311 HKATVSGVTCSA 322
             ++++GV   A
Sbjct: 200 CGSSINGVAVGA 211


>BC119693-1|AAI19694.1|  441|Homo sapiens WDR51A protein protein.
          Length = 441

 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 69/302 (22%), Positives = 127/302 (42%), Gaps = 13/302 (4%)

Query: 131 AKDDIEKEKEYDSDRDA----EQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKV 186
           +++D   E+ +   RDA    +   N  ++ S   D  LM   +       A R    K 
Sbjct: 39  SQEDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQ--SRAYRFTGHKD 96

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
            +T V +     LL +G       +  +P+V    T+    H  +  SV    D  +F  
Sbjct: 97  AVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTV-FRAHTATVRSVHFCSDGQSFVT 154

Query: 247 PNIGQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCF 305
            +  + + VW    ++++     H   + C  +SPDG  +V+   D  VK+W+ ++  C 
Sbjct: 155 ASDDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECV 214

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
            ++ EH   V+ V    +     ++ +D TV+ +D+  +R  +     S    + ++   
Sbjct: 215 HSYCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHS-AAVNGLSFHP 273

Query: 366 SGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVR 425
           SG +      D   + +  +  G+LL  L GH+ P +++AFS   T    AS   D  V 
Sbjct: 274 SGNYLITASSD-STLKILDLMEGRLLYTLHGHQGPATTVAFS--RTGEYFASGGSDEQVM 330

Query: 426 LW 427
           +W
Sbjct: 331 VW 332



 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 55/207 (26%), Positives = 80/207 (38%), Gaps = 4/207 (1%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +TC+ +S +   + +G  D  + VW+         F  HK  V+ V  S +   
Sbjct: 50  KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 109

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIK 386
             S S D TVR + +   +   T+          V   S G+       D   + VW+  
Sbjct: 110 LASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK-TVKVWATH 167

Query: 387 FGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL 446
             K L  L  H   V    FSP      + SAS D TV+LWD   RE             
Sbjct: 168 RQKFLFSLSQHINWVRCAKFSPD--GRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVT 225

Query: 447 QVAFRPDGEEIAVSTLDGNITFFEPST 473
            V F P G  IA + +D  +  ++  T
Sbjct: 226 YVDFHPSGTCIAAAGMDNTVKVWDVRT 252



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 61/297 (20%), Positives = 119/297 (40%), Gaps = 20/297 (6%)

Query: 16  MKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVF 75
           ++R FK   D VTC+D+S  ++ LA GS D+   +  ++       Y  +GH D +  V 
Sbjct: 45  LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMK--PQSRAYRFTGHKDAVTCVN 102

Query: 76  FERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDI 135
           F      L + SR+  + +W  ++   E  V +  T+  + V   ++G   + F    D 
Sbjct: 103 FSPSGHLLASGSRDKTVRIWVPNVKG-ESTVFRAHTATVRSVHFCSDG---QSFVTASDD 158

Query: 136 EKEKEYDSDR-----DAEQEQNNSKVNSEENDKRLMYK-------KLGRHYIGDAIRN-A 182
           +  K + + R        Q  N  +      D RL+         KL      + + +  
Sbjct: 159 KTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYC 218

Query: 183 DRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWI 242
           +    +T V +H     +          + ++    L+    +    ++ +S  P G+++
Sbjct: 219 EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYL 278

Query: 243 AFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNT 299
             A  +   L + +    + +    GH    T +A+S  G +  +GG D +V VW +
Sbjct: 279 ITASSD-STLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 334


>BC021541-1|AAH21541.1|  392|Homo sapiens WD repeat domain 71
           protein.
          Length = 392

 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 6/134 (4%)

Query: 210 FLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGH 269
           FL      + IHT SI+      + +S  G  +  +    G + +W+  + +     +GH
Sbjct: 80  FLAPYTTFSRIHTKSIT-----CLDISSRGG-LGVSSSTDGTMKIWQASNGELRRVLEGH 133

Query: 270 SLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVS 329
             D+ C  + P GL V++GG D ++K+W+  +  C VTF  HK  +         +  VS
Sbjct: 134 VFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVS 193

Query: 330 SSLDGTVRCYDLTR 343
           +S DGT R +D  R
Sbjct: 194 ASRDGTARLWDCGR 207



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 5/126 (3%)

Query: 305 FVTFHE-HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           + TF   H  +++ +  S+     VSSS DGT++ +  +     R +    +   +C   
Sbjct: 84  YTTFSRIHTKSITCLDISSRGGLGVSSSTDGTMKIWQASN-GELRRVLEGHVFDVNCCRF 142

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
             SG    +GG D  ++ +WS +    +    GH+  +   A         + SAS DGT
Sbjct: 143 FPSGLVVLSGGMDA-QLKIWSAEDASCVVTFKGHKGGILDTAIVDR--GRNVVSASRDGT 199

Query: 424 VRLWDC 429
            RLWDC
Sbjct: 200 ARLWDC 205



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 17/72 (23%), Positives = 32/72 (44%)

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           QL +W  +    V+  +GH   +   A    G +VV+   DG  ++W+     C     +
Sbjct: 157 QLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSGCLGVLAD 216

Query: 311 HKATVSGVTCSA 322
             ++++GV   A
Sbjct: 217 CGSSINGVAVGA 228


>BC006142-1|AAH06142.2|  392|Homo sapiens WD repeat domain 71
           protein.
          Length = 392

 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 6/134 (4%)

Query: 210 FLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGH 269
           FL      + IHT SI+      + +S  G  +  +    G + +W+  + +     +GH
Sbjct: 80  FLAPYTTFSRIHTKSIT-----CLDISSRGG-LGVSSSTDGTMKIWQASNGELRRVLEGH 133

Query: 270 SLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVS 329
             D+ C  + P GL V++GG D ++K+W+  +  C VTF  HK  +         +  VS
Sbjct: 134 VFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVS 193

Query: 330 SSLDGTVRCYDLTR 343
           +S DGT R +D  R
Sbjct: 194 ASRDGTARLWDCGR 207



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 5/126 (3%)

Query: 305 FVTFHE-HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           + TF   H  +++ +  S+     VSSS DGT++ +  +     R +    +   +C   
Sbjct: 84  YTTFSRIHTKSITCLDISSRGGLGVSSSTDGTMKIWQASN-GELRRVLEGHVFDVNCCRF 142

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
             SG    +GG D  ++ +WS +    +    GH+  +   A         + SAS DGT
Sbjct: 143 FPSGLVVLSGGMDA-QLKIWSAEDASCVVTFKGHKGGILDTAIVDR--GRNVVSASRDGT 199

Query: 424 VRLWDC 429
            RLWDC
Sbjct: 200 ARLWDC 205



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 17/72 (23%), Positives = 32/72 (44%)

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           QL +W  +    V+  +GH   +   A    G +VV+   DG  ++W+     C     +
Sbjct: 157 QLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSACLGVLAD 216

Query: 311 HKATVSGVTCSA 322
             ++++GV   A
Sbjct: 217 CGSSINGVAVGA 228


>AK021910-1|BAB13933.1|  392|Homo sapiens protein ( Homo sapiens
           cDNA FLJ11848 fis, clone HEMBA1006708, weakly similar to
           HYPOTHETICAL 46.4 KD TRP-ASP REPEATS CONTAINING PROTEIN
           IN ).
          Length = 392

 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 39/134 (29%), Positives = 64/134 (47%), Gaps = 6/134 (4%)

Query: 210 FLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGH 269
           FL      + IHT SI+      + +S  G  +  +    G + +W+  + +     +GH
Sbjct: 80  FLAPYTTFSRIHTKSIT-----CLDISSRGG-LGVSSSTDGTMKIWQASNGELRRVLEGH 133

Query: 270 SLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVS 329
             D+ C  + P GL V++GG D ++K+W+  +  C VTF  HK  +         +  VS
Sbjct: 134 VFDVNCCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVS 193

Query: 330 SSLDGTVRCYDLTR 343
           +S DGT R +D  R
Sbjct: 194 ASRDGTARLWDCGR 207



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 34/126 (26%), Positives = 56/126 (44%), Gaps = 5/126 (3%)

Query: 305 FVTFHE-HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           + TF   H  +++ +  S+     VSSS DGT++ +  +     R +    +   +C   
Sbjct: 84  YTTFSRIHTKSITCLDISSRGGLGVSSSTDGTMKIWQASN-GELRRVLEGHVFDVNCCRF 142

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
             SG    +GG D  ++ +WS +    +    GH+  +   A         + SAS DGT
Sbjct: 143 FPSGLVVLSGGMDA-QLKIWSAEDASCVVTFKGHKGGILDTAIVDR--GRNVVSASRDGT 199

Query: 424 VRLWDC 429
            RLWDC
Sbjct: 200 ARLWDC 205



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 17/72 (23%), Positives = 32/72 (44%)

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           QL +W  +    V+  +GH   +   A    G +VV+   DG  ++W+     C     +
Sbjct: 157 QLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSACLGVLAD 216

Query: 311 HKATVSGVTCSA 322
             ++++GV   A
Sbjct: 217 CGSSINGVAVGA 228


>AF268193-1|AAG44736.1|  514|Homo sapiens IRA1 protein.
          Length = 514

 Score = 70.1 bits (164), Expect = 3e-11
 Identities = 57/222 (25%), Positives = 95/222 (42%), Gaps = 12/222 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G  +++ G D    +W+   G     F  H A    V   +N  F  
Sbjct: 265 HKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQSNNTF-A 323

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L + R  +T    +  + + +  D +G   A+   D+  + +WS+K  
Sbjct: 324 SCSTDMCIHVCKLGQDRPIKTFQGHTN-EVNAIKWDPTGNLLASCSDDM-TLKIWSMKQD 381

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT   T        LASAS+D TVRLWD +DR +    +  
Sbjct: 382 NCVHDLQQHNKEIYTIKWSPTGPGTNNPNANLMLASASFDSTVRLWD-VDRGICIHTLTK 440

Query: 442 NSDAL-QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
           + + +  VAF PDG  +A  + D  +  +   T     S  G
Sbjct: 441 HQEPVYSVAFSPDGRYLASGSFDKCVHIWNTQTGALVHSYRG 482



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 31/130 (23%), Positives = 59/130 (45%), Gaps = 10/130 (7%)

Query: 220 IHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYS 279
           I T     + +++I   P G+ +A +C +   L +W  + +  V   Q H+ ++  + +S
Sbjct: 342 IKTFQGHTNEVNAIKWDPTGNLLA-SCSDDMTLKIWSMKQDNCVHDLQQHNKEIYTIKWS 400

Query: 280 PDG---------LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSS 330
           P G         L + +  FD  V++W+   G C  T  +H+  V  V  S + ++  S 
Sbjct: 401 PTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASG 460

Query: 331 SLDGTVRCYD 340
           S D  V  ++
Sbjct: 461 SFDKCVHIWN 470



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 44/186 (23%), Positives = 84/186 (45%), Gaps = 12/186 (6%)

Query: 272 DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSS 331
           D+T L ++ +G  + TG +DG  ++W T +G    T  +HK  +  +  +    F +S+ 
Sbjct: 227 DVTSLDWNSEGTLLATGSYDGFARIW-TKDGNLASTLGQHKGPIFALKWNKKGNFILSAG 285

Query: 332 LDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           +D T   +D       + F   ++P+L     V   S+  F A+   D+  I V  +   
Sbjct: 286 VDKTTIIWDAHTGEAKQQFPFHSAPAL----DVDWQSNNTF-ASCSTDMC-IHVCKLGQD 339

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQV 448
           + ++   GH   V+++ + P  T   LAS S D T+++W         +  + N +   +
Sbjct: 340 RPIKTFQGHTNEVNAIKWDP--TGNLLASCSDDMTLKIWSMKQDNCVHDLQQHNKEIYTI 397

Query: 449 AFRPDG 454
            + P G
Sbjct: 398 KWSPTG 403



 Score = 41.9 bits (94), Expect = 0.008
 Identities = 38/167 (22%), Positives = 67/167 (40%), Gaps = 13/167 (7%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++ A+++     LL +        +  M   N +H L      I +I  SP G       
Sbjct: 351 EVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQQHNKEIYTIKWSPTGPGTNNPN 410

Query: 247 PNI--------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN 298
            N+          + +W+      +     H   +  +A+SPDG ++ +G FD  V +WN
Sbjct: 411 ANLMLASASFDSTVRLWDVDRGICIHTLTKHQEPVYSVAFSPDGRYLASGSFDKCVHIWN 470

Query: 299 TTNGFCFVTFHEHKAT--VSGVTCSANKKFFVSSSLDGTVRCYDLTR 343
           T  G      H ++ T  +  V  +A      +S+ DG+V   DL +
Sbjct: 471 TQTG---ALVHSYRGTGGIFEVCWNAAGDKVGASASDGSVCVLDLRK 514



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           +VT LDW+S   LLA GS D   +I T +   N+   +L  H   I  + + +K   +++
Sbjct: 227 DVTSLDWNSEGTLLATGSYDGFARIWTKD--GNLAS-TLGQHKGPIFALKWNKKGNFILS 283

Query: 86  VSRNGQLCLWEA 97
              +    +W+A
Sbjct: 284 AGVDKTTIIWDA 295



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 25/90 (27%), Positives = 40/90 (44%), Gaps = 6/90 (6%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP 452
           VL GHE+ V   A++P   S  LAS S D T R+W+  +              L+   R 
Sbjct: 164 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWNLSENSTSGS----TQLVLRHCIRE 217

Query: 453 DGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
            G+++  +    ++ +    T   TGS +G
Sbjct: 218 GGQDVPSNKDVTSLDWNSEGTLLATGSYDG 247


>BC119692-1|AAI19693.1|  407|Homo sapiens WD repeat domain 51A
           protein.
          Length = 407

 Score = 69.3 bits (162), Expect = 5e-11
 Identities = 69/300 (23%), Positives = 125/300 (41%), Gaps = 13/300 (4%)

Query: 133 DDIEKEKEYDSDRDA----EQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKL 188
           +D   E+ +   RDA    +   N  ++ S   D  LM   +       A R    K  +
Sbjct: 7   EDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQ--SRAYRFTGHKDAV 64

Query: 189 TAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPN 248
           T V +     LL +G       +  +P+V    T+    H  +  SV    D  +F   +
Sbjct: 65  TCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTV-FRAHTATVRSVHFCSDGQSFVTAS 122

Query: 249 IGQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
             + + VW    ++++     H   + C  +SPDG  +V+   D  VK+W+ ++  C  +
Sbjct: 123 DDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 182

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSG 367
           + EH   V+ V    +     ++ +D TV+ +D+  +R  +     S    + ++   SG
Sbjct: 183 YCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHS-AAVNGLSFHPSG 241

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
            +      D   + +  +  G+LL  L GH+ P +++AFS   T    AS   D  V +W
Sbjct: 242 NYLITASSD-STLKILDLMEGRLLYTLHGHQGPATTVAFS--RTGEYFASGGSDEQVMVW 298



 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 55/207 (26%), Positives = 80/207 (38%), Gaps = 4/207 (1%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +TC+ +S +   + +G  D  + VW+         F  HK  V+ V  S +   
Sbjct: 16  KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 75

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIK 386
             S S D TVR + +   +   T+          V   S G+       D   + VW+  
Sbjct: 76  LASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK-TVKVWATH 133

Query: 387 FGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL 446
             K L  L  H   V    FSP      + SAS D TV+LWD   RE             
Sbjct: 134 RQKFLFSLSQHINWVRCAKFSPD--GRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVT 191

Query: 447 QVAFRPDGEEIAVSTLDGNITFFEPST 473
            V F P G  IA + +D  +  ++  T
Sbjct: 192 YVDFHPSGTCIAAAGMDNTVKVWDVRT 218



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 61/297 (20%), Positives = 119/297 (40%), Gaps = 20/297 (6%)

Query: 16  MKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVF 75
           ++R FK   D VTC+D+S  ++ LA GS D+   +  ++       Y  +GH D +  V 
Sbjct: 11  LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMK--PQSRAYRFTGHKDAVTCVN 68

Query: 76  FERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDI 135
           F      L + SR+  + +W  ++   E  V +  T+  + V   ++G   + F    D 
Sbjct: 69  FSPSGHLLASGSRDKTVRIWVPNVKG-ESTVFRAHTATVRSVHFCSDG---QSFVTASDD 124

Query: 136 EKEKEYDSDR-----DAEQEQNNSKVNSEENDKRLMYK-------KLGRHYIGDAIRN-A 182
           +  K + + R        Q  N  +      D RL+         KL      + + +  
Sbjct: 125 KTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYC 184

Query: 183 DRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWI 242
           +    +T V +H     +          + ++    L+    +    ++ +S  P G+++
Sbjct: 185 EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYL 244

Query: 243 AFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNT 299
             A  +   L + +    + +    GH    T +A+S  G +  +GG D +V VW +
Sbjct: 245 ITASSD-STLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300


>BC110877-1|AAI10878.1|  359|Homo sapiens WDR51A protein protein.
          Length = 359

 Score = 69.3 bits (162), Expect = 5e-11
 Identities = 69/300 (23%), Positives = 125/300 (41%), Gaps = 13/300 (4%)

Query: 133 DDIEKEKEYDSDRDA----EQEQNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKL 188
           +D   E+ +   RDA    +   N  ++ S   D  LM   +       A R    K  +
Sbjct: 7   EDPSLERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQ--SRAYRFTGHKDAV 64

Query: 189 TAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPN 248
           T V +     LL +G       +  +P+V    T+    H  +  SV    D  +F   +
Sbjct: 65  TCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTV-FRAHTATVRSVHFCSDGQSFVTAS 122

Query: 249 IGQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
             + + VW    ++++     H   + C  +SPDG  +V+   D  VK+W+ ++  C  +
Sbjct: 123 DDKTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHS 182

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSG 367
           + EH   V+ V    +     ++ +D TV+ +D+  +R  +     S    + ++   SG
Sbjct: 183 YCEHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHS-AAVNGLSFHPSG 241

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
            +      D   + +  +  G+LL  L GH+ P +++AFS   T    AS   D  V +W
Sbjct: 242 NYLITASSD-STLKILDLMEGRLLYTLHGHQGPATTVAFS--RTGEYFASGGSDEQVMVW 298



 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 55/207 (26%), Positives = 80/207 (38%), Gaps = 4/207 (1%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GH   +TC+ +S +   + +G  D  + VW+         F  HK  V+ V  S +   
Sbjct: 16  KGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHKDAVTCVNFSPSGHL 75

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIK 386
             S S D TVR + +   +   T+          V   S G+       D   + VW+  
Sbjct: 76  LASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK-TVKVWATH 133

Query: 387 FGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDAL 446
             K L  L  H   V    FSP      + SAS D TV+LWD   RE             
Sbjct: 134 RQKFLFSLSQHINWVRCAKFSPD--GRLIVSASDDKTVKLWDKSSRECVHSYCEHGGFVT 191

Query: 447 QVAFRPDGEEIAVSTLDGNITFFEPST 473
            V F P G  IA + +D  +  ++  T
Sbjct: 192 YVDFHPSGTCIAAAGMDNTVKVWDVRT 218



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 61/297 (20%), Positives = 119/297 (40%), Gaps = 20/297 (6%)

Query: 16  MKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVF 75
           ++R FK   D VTC+D+S  ++ LA GS D+   +  ++       Y  +GH D +  V 
Sbjct: 11  LERHFKGHRDAVTCVDFSINTKQLASGSMDSCLMVWHMK--PQSRAYRFTGHKDAVTCVN 68

Query: 76  FERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDI 135
           F      L + SR+  + +W  ++   E  V +  T+  + V   ++G   + F    D 
Sbjct: 69  FSPSGHLLASGSRDKTVRIWVPNVKG-ESTVFRAHTATVRSVHFCSDG---QSFVTASDD 124

Query: 136 EKEKEYDSDR-----DAEQEQNNSKVNSEENDKRLMYK-------KLGRHYIGDAIRN-A 182
           +  K + + R        Q  N  +      D RL+         KL      + + +  
Sbjct: 125 KTVKVWATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDKTVKLWDKSSRECVHSYC 184

Query: 183 DRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWI 242
           +    +T V +H     +          + ++    L+    +    ++ +S  P G+++
Sbjct: 185 EHGGFVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAAVNGLSFHPSGNYL 244

Query: 243 AFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNT 299
             A  +   L + +    + +    GH    T +A+S  G +  +GG D +V VW +
Sbjct: 245 ITASSD-STLKILDLMEGRLLYTLHGHQGPATTVAFSRTGEYFASGGSDEQVMVWKS 300


>BC015920-1|AAH15920.1|  297|Homo sapiens GNB3 protein protein.
          Length = 297

 Score = 69.3 bits (162), Expect = 5e-11
 Identities = 52/247 (21%), Positives = 105/247 (42%), Gaps = 11/247 (4%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           K+ A+ +  ++KLLV+    G   + +    N +H + +    + + + +P G+++  AC
Sbjct: 57  KIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGNFV--AC 114

Query: 247 PNIGQLL-VWEWQSEQYVMK----QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
             +  +  ++  +S +  +K       H+  ++C  +  D  ++VT   D    +W+   
Sbjct: 115 GGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDN-NIVTSSGDTTCALWDIET 173

Query: 302 GFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
           G     F  H      +  S +   F+S + D + + +D+      +T T       +  
Sbjct: 174 GQQKTVFVGHTGDCMSLAVSPDFNLFISGACDASAKLWDVREGTCRQTFTGHESDINAIC 233

Query: 362 ALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               SG    AG  D F   VW     + + +L GH+  VS L    T     +A+ SWD
Sbjct: 234 FFSLSGRLLFAGYDD-FNCNVWDSMKSERVGILSGHDNRVSCLGV--TADGMAVATGSWD 290

Query: 422 GTVRLWD 428
             +++W+
Sbjct: 291 SFLKIWN 297



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 55/228 (24%), Positives = 86/228 (37%), Gaps = 18/228 (7%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANK 324
           +GH   +  + ++ D   +V+   DGK+ VW+  TTN    +              S N 
Sbjct: 52  RGHLAKIYAMHWATDSKLLVSASQDGKLIVWDSYTTNKVHAIPLRSSWVMTCAYAPSGN- 110

Query: 325 KFFVSSSLDGTVRCYDL-TRYRNF---RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
            F     LD     Y+L +R  N    R L++ +     C  LD +    ++G       
Sbjct: 111 -FVACGGLDNMCSIYNLKSREGNVKVSRELSAHTGYLSCCRFLDDNNIVTSSGDT---TC 166

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+ G+   V  GH     SLA SP        S + D + +LWD   RE  C    
Sbjct: 167 ALWDIETGQQKTVFVGHTGDCMSLAVSPDF--NLFISGACDASAKLWDV--REGTCRQTF 222

Query: 441 L--NSDALQVA-FRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSD 485
               SD   +  F   G  +     D N   ++    E+ G + G  +
Sbjct: 223 TGHESDINAICFFSLSGRLLFAGYDDFNCNVWDSMKSERVGILSGHDN 270


>AF208838-1|AAL34973.1|  410|Homo sapiens Miller-Dieker
           lissencephaly protein protein.
          Length = 410

 Score = 68.5 bits (160), Expect = 8e-11
 Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 25/259 (9%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           + +    KLL +  +     L +      I T+   +H +SS+++ P GD I  A  +  
Sbjct: 156 ISFDHSGKLLASCSADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD-K 214

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
            + +WE Q+   V    GH   +  +  + DG  + +   D  V+VW      C     E
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 274

Query: 311 HK--------------ATVSGVTCSANKK------FFVSSSLDGTVRCYDLTRYRNFRTL 350
           H+              +++S  T S  KK      F +S S D T++ +D++      TL
Sbjct: 275 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 334

Query: 351 TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTL 410
                     V   S G+F  +   D   + VW  K  + ++ L  HE  V+SL F    
Sbjct: 335 VGHDN-WVRGVLFHSGGKFILSCADDK-TLRVWDYKNKRCMKTLNAHEHFVTSLDFHK-- 390

Query: 411 TSTRLASASWDGTVRLWDC 429
           T+  + + S D TV++W+C
Sbjct: 391 TAPYVVTGSVDQTVKVWEC 409



 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 51/209 (24%), Positives = 94/209 (44%), Gaps = 8/209 (3%)

Query: 260 EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVT 319
           E+Y +   GH   +T + + P    +V+   D  +KVW+   G    T   H  +V  ++
Sbjct: 100 EKYALS--GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDIS 157

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFE 379
              + K   S S D T++  D   +   RT+        S VA+  +G+   +  +D   
Sbjct: 158 FDHSGKLLASCSADMTIKLRDFQGFECIRTMHGHD-HNVSSVAIMPNGDHIVSASRDK-T 215

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I +W ++ G  ++   GH   V  +   P    T +AS S D TVR+W    +E + E +
Sbjct: 216 IKMWEVQTGYCVKTFTGHREWVRMV--RPNQDGTLIASCSNDQTVRVWVVATKECKAE-L 272

Query: 440 RLNSDALQ-VAFRPDGEEIAVSTLDGNIT 467
           R +   ++ +++ P+    ++S   G+ T
Sbjct: 273 REHEHVVECISWAPESSYSSISEATGSET 301



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 59/260 (22%), Positives = 105/260 (40%), Gaps = 23/260 (8%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +T V +H    ++V+        + +    +   TL      +  IS    G  +A +C 
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLA-SCS 169

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
               + + ++Q  + +    GH  +++ +A  P+G H+V+   D  +K+W    G+C  T
Sbjct: 170 ADMTIKLRDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTSPSLVQFSCVALDSS 366
           F  H+  V  V  + +     S S D TVR + + T+           +V+    A +SS
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 289

Query: 367 ------------------GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
                             G F  +G +D   I +W +  G  L  L GH+  V  + F  
Sbjct: 290 YSSISEATGSETKKSGKPGPFLLSGSRDK-TIKMWDVSTGMCLMTLVGHDNWVRGVLFHS 348

Query: 409 TLTSTRLASASWDGTVRLWD 428
                 + S + D T+R+WD
Sbjct: 349 --GGKFILSCADDKTLRVWD 366


>U72342-1|AAC51111.1|  410|Homo sapiens platelet activating factor
           acetylhydrolase, brain isoform, 45 kDa subunit protein.
          Length = 410

 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 25/259 (9%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           + +    KLL +  +     L +      I T+   +H +SS+++ P GD I  A  +  
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD-K 214

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
            + +WE Q+   V    GH   +  +  + DG  + +   D  V+VW      C     E
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 274

Query: 311 HK--------------ATVSGVTCSANKK------FFVSSSLDGTVRCYDLTRYRNFRTL 350
           H+              +++S  T S  KK      F +S S D T++ +D++      TL
Sbjct: 275 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 334

Query: 351 TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTL 410
                     V   S G+F  +   D   + VW  K  + ++ L  HE  V+SL F    
Sbjct: 335 VGHDN-WVRGVLFHSGGKFILSCADDK-TLRVWDYKNKRCMKTLNAHEHFVTSLDFHK-- 390

Query: 411 TSTRLASASWDGTVRLWDC 429
           T+  + + S D TV++W+C
Sbjct: 391 TAPYVVTGSVDQTVKVWEC 409



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 51/209 (24%), Positives = 95/209 (45%), Gaps = 8/209 (3%)

Query: 260 EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVT 319
           E+Y +   GH   +T + + P    +V+   D  +KVW+   G    T   H  +V  ++
Sbjct: 100 EKYALS--GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDIS 157

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFE 379
              + K   S S D T++ +D   +   RT+        S VA+  +G+   +  +D   
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHD-HNVSSVAIMPNGDHIVSASRDK-T 215

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I +W ++ G  ++   GH   V  +   P    T +AS S D TVR+W    +E + E +
Sbjct: 216 IKMWEVQTGYCVKTFTGHREWVRMV--RPNQDGTLIASCSNDQTVRVWVVATKECKAE-L 272

Query: 440 RLNSDALQ-VAFRPDGEEIAVSTLDGNIT 467
           R +   ++ +++ P+    ++S   G+ T
Sbjct: 273 REHEHVVECISWAPESSYSSISEATGSET 301



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 60/260 (23%), Positives = 106/260 (40%), Gaps = 23/260 (8%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +T V +H    ++V+        + +    +   TL      +  IS    G  +A +C 
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLA-SCS 169

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
               + +W++Q  + +    GH  +++ +A  P+G H+V+   D  +K+W    G+C  T
Sbjct: 170 ADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTSPSLVQFSCVALDSS 366
           F  H+  V  V  + +     S S D TVR + + T+           +V+    A +SS
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 289

Query: 367 ------------------GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
                             G F  +G +D   I +W +  G  L  L GH+  V  + F  
Sbjct: 290 YSSISEATGSETKKSGKPGPFLLSGSRDK-TIKMWDVSTGMCLMTLVGHDNWVRGVLFHS 348

Query: 409 TLTSTRLASASWDGTVRLWD 428
                 + S + D T+R+WD
Sbjct: 349 --GGKFILSCADDKTLRVWD 366


>L13386-1|AAA02881.1|  410|Homo sapiens Miller-Dieker lissencephaly
           protein protein.
          Length = 410

 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 25/259 (9%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           + +    KLL +  +     L +      I T+   +H +SS+++ P GD I  A  +  
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD-K 214

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
            + +WE Q+   V    GH   +  +  + DG  + +   D  V+VW      C     E
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 274

Query: 311 HK--------------ATVSGVTCSANKK------FFVSSSLDGTVRCYDLTRYRNFRTL 350
           H+              +++S  T S  KK      F +S S D T++ +D++      TL
Sbjct: 275 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 334

Query: 351 TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTL 410
                     V   S G+F  +   D   + VW  K  + ++ L  HE  V+SL F    
Sbjct: 335 VGHDN-WVRGVLFHSGGKFILSCADDK-TLRVWDYKNKRCMKTLNAHEHFVTSLDFHK-- 390

Query: 411 TSTRLASASWDGTVRLWDC 429
           T+  + + S D TV++W+C
Sbjct: 391 TAPYVVTGSVDQTVKVWEC 409



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 51/209 (24%), Positives = 95/209 (45%), Gaps = 8/209 (3%)

Query: 260 EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVT 319
           E+Y +   GH   +T + + P    +V+   D  +KVW+   G    T   H  +V  ++
Sbjct: 100 EKYALS--GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDIS 157

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFE 379
              + K   S S D T++ +D   +   RT+        S VA+  +G+   +  +D   
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHD-HNVSSVAIMPNGDHIVSASRDK-T 215

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I +W ++ G  ++   GH   V  +   P    T +AS S D TVR+W    +E + E +
Sbjct: 216 IKMWEVQTGYCVKTFTGHREWVRMV--RPNQDGTLIASCSNDQTVRVWVVATKECKAE-L 272

Query: 440 RLNSDALQ-VAFRPDGEEIAVSTLDGNIT 467
           R +   ++ +++ P+    ++S   G+ T
Sbjct: 273 REHEHVVECISWAPESSYSSISEATGSET 301



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 60/260 (23%), Positives = 106/260 (40%), Gaps = 23/260 (8%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +T V +H    ++V+        + +    +   TL      +  IS    G  +A +C 
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLA-SCS 169

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
               + +W++Q  + +    GH  +++ +A  P+G H+V+   D  +K+W    G+C  T
Sbjct: 170 ADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTSPSLVQFSCVALDSS 366
           F  H+  V  V  + +     S S D TVR + + T+           +V+    A +SS
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 289

Query: 367 ------------------GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
                             G F  +G +D   I +W +  G  L  L GH+  V  + F  
Sbjct: 290 YSSISEATGSETKKSGKPGPFLLSGSRDK-TIKMWDVSTGMCLMTLVGHDNWVRGVLFHS 348

Query: 409 TLTSTRLASASWDGTVRLWD 428
                 + S + D T+R+WD
Sbjct: 349 --GGKFILSCADDKTLRVWD 366


>L13385-1|AAA02880.1|  410|Homo sapiens Miller-Dieker lissencephaly
           protein protein.
          Length = 410

 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 25/259 (9%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           + +    KLL +  +     L +      I T+   +H +SS+++ P GD I  A  +  
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD-K 214

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
            + +WE Q+   V    GH   +  +  + DG  + +   D  V+VW      C     E
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 274

Query: 311 HK--------------ATVSGVTCSANKK------FFVSSSLDGTVRCYDLTRYRNFRTL 350
           H+              +++S  T S  KK      F +S S D T++ +D++      TL
Sbjct: 275 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 334

Query: 351 TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTL 410
                     V   S G+F  +   D   + VW  K  + ++ L  HE  V+SL F    
Sbjct: 335 VGHDN-WVRGVLFHSGGKFILSCADDK-TLRVWDYKNKRCMKTLNAHEHFVTSLDFHK-- 390

Query: 411 TSTRLASASWDGTVRLWDC 429
           T+  + + S D TV++W+C
Sbjct: 391 TAPYVVTGSVDQTVKVWEC 409



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 51/209 (24%), Positives = 95/209 (45%), Gaps = 8/209 (3%)

Query: 260 EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVT 319
           E+Y +   GH   +T + + P    +V+   D  +KVW+   G    T   H  +V  ++
Sbjct: 100 EKYALS--GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDIS 157

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFE 379
              + K   S S D T++ +D   +   RT+        S VA+  +G+   +  +D   
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHD-HNVSSVAIMPNGDHIVSASRDK-T 215

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I +W ++ G  ++   GH   V  +   P    T +AS S D TVR+W    +E + E +
Sbjct: 216 IKMWEVQTGYCVKTFTGHREWVRMV--RPNQDGTLIASCSNDQTVRVWVVATKECKAE-L 272

Query: 440 RLNSDALQ-VAFRPDGEEIAVSTLDGNIT 467
           R +   ++ +++ P+    ++S   G+ T
Sbjct: 273 REHEHVVECISWAPESSYSSISEATGSET 301



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 60/260 (23%), Positives = 106/260 (40%), Gaps = 23/260 (8%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +T V +H    ++V+        + +    +   TL      +  IS    G  +A +C 
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLA-SCS 169

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
               + +W++Q  + +    GH  +++ +A  P+G H+V+   D  +K+W    G+C  T
Sbjct: 170 ADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTSPSLVQFSCVALDSS 366
           F  H+  V  V  + +     S S D TVR + + T+           +V+    A +SS
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 289

Query: 367 ------------------GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
                             G F  +G +D   I +W +  G  L  L GH+  V  + F  
Sbjct: 290 YSSISEATGSETKKSGKPGPFLLSGSRDK-TIKMWDVSTGMCLMTLVGHDNWVRGVLFHS 348

Query: 409 TLTSTRLASASWDGTVRLWD 428
                 + S + D T+R+WD
Sbjct: 349 --GGKFILSCADDKTLRVWD 366


>BC064638-1|AAH64638.1|  410|Homo sapiens platelet-activating factor
           acetylhydrolase, isoform Ib, alpha subunit 45kDa
           protein.
          Length = 410

 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 25/259 (9%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           + +    KLL +  +     L +      I T+   +H +SS+++ P GD I  A  +  
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD-K 214

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
            + +WE Q+   V    GH   +  +  + DG  + +   D  V+VW      C     E
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 274

Query: 311 HK--------------ATVSGVTCSANKK------FFVSSSLDGTVRCYDLTRYRNFRTL 350
           H+              +++S  T S  KK      F +S S D T++ +D++      TL
Sbjct: 275 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 334

Query: 351 TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTL 410
                     V   S G+F  +   D   + VW  K  + ++ L  HE  V+SL F    
Sbjct: 335 VGHDN-WVRGVLFHSGGKFILSCADDK-TLRVWDYKNKRCMKTLNAHEHFVTSLDFHK-- 390

Query: 411 TSTRLASASWDGTVRLWDC 429
           T+  + + S D TV++W+C
Sbjct: 391 TAPYVVTGSVDQTVKVWEC 409



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 51/209 (24%), Positives = 95/209 (45%), Gaps = 8/209 (3%)

Query: 260 EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVT 319
           E+Y +   GH   +T + + P    +V+   D  +KVW+   G    T   H  +V  ++
Sbjct: 100 EKYALS--GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDIS 157

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFE 379
              + K   S S D T++ +D   +   RT+        S VA+  +G+   +  +D   
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHD-HNVSSVAIMPNGDHIVSASRDK-T 215

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I +W ++ G  ++   GH   V  +   P    T +AS S D TVR+W    +E + E +
Sbjct: 216 IKMWEVQTGYCVKTFTGHREWVRMV--RPNQDGTLIASCSNDQTVRVWVVATKECKAE-L 272

Query: 440 RLNSDALQ-VAFRPDGEEIAVSTLDGNIT 467
           R +   ++ +++ P+    ++S   G+ T
Sbjct: 273 REHEHVVECISWAPESSYSSISEATGSET 301



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 60/260 (23%), Positives = 106/260 (40%), Gaps = 23/260 (8%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +T V +H    ++V+        + +    +   TL      +  IS    G  +A +C 
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLA-SCS 169

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
               + +W++Q  + +    GH  +++ +A  P+G H+V+   D  +K+W    G+C  T
Sbjct: 170 ADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTSPSLVQFSCVALDSS 366
           F  H+  V  V  + +     S S D TVR + + T+           +V+    A +SS
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 289

Query: 367 ------------------GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
                             G F  +G +D   I +W +  G  L  L GH+  V  + F  
Sbjct: 290 YSSISEATGSETKKSGKPGPFLLSGSRDK-TIKMWDVSTGMCLMTLVGHDNWVRGVLFHS 348

Query: 409 TLTSTRLASASWDGTVRLWD 428
                 + S + D T+R+WD
Sbjct: 349 --GGKFILSCADDKTLRVWD 366


>AF400434-1|AAK92483.1|  410|Homo sapiens platelet-activating factor
           acetyl hydrolase isoform Ib alpha subunit protein.
          Length = 410

 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 25/259 (9%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           + +    KLL +  +     L +      I T+   +H +SS+++ P GD I  A  +  
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD-K 214

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
            + +WE Q+   V    GH   +  +  + DG  + +   D  V+VW      C     E
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 274

Query: 311 HK--------------ATVSGVTCSANKK------FFVSSSLDGTVRCYDLTRYRNFRTL 350
           H+              +++S  T S  KK      F +S S D T++ +D++      TL
Sbjct: 275 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 334

Query: 351 TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTL 410
                     V   S G+F  +   D   + VW  K  + ++ L  HE  V+SL F    
Sbjct: 335 VGHDN-WVRGVLFHSGGKFILSCADDK-TLRVWDYKNKRCMKTLNAHEHFVTSLDFHK-- 390

Query: 411 TSTRLASASWDGTVRLWDC 429
           T+  + + S D TV++W+C
Sbjct: 391 TAPYVVTGSVDQTVKVWEC 409



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 51/209 (24%), Positives = 95/209 (45%), Gaps = 8/209 (3%)

Query: 260 EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVT 319
           E+Y +   GH   +T + + P    +V+   D  +KVW+   G    T   H  +V  ++
Sbjct: 100 EKYALS--GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDIS 157

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFE 379
              + K   S S D T++ +D   +   RT+        S VA+  +G+   +  +D   
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHD-HNVSSVAIMPNGDHIVSASRDK-T 215

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I +W ++ G  ++   GH   V  +   P    T +AS S D TVR+W    +E + E +
Sbjct: 216 IKMWEVQTGYCVKTFTGHREWVRMV--RPNQDGTLIASCSNDQTVRVWVVATKECKAE-L 272

Query: 440 RLNSDALQ-VAFRPDGEEIAVSTLDGNIT 467
           R +   ++ +++ P+    ++S   G+ T
Sbjct: 273 REHEHVVECISWAPESSYSSISEATGSET 301



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 60/260 (23%), Positives = 106/260 (40%), Gaps = 23/260 (8%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +T V +H    ++V+        + +    +   TL      +  IS    G  +A +C 
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLA-SCS 169

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
               + +W++Q  + +    GH  +++ +A  P+G H+V+   D  +K+W    G+C  T
Sbjct: 170 ADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTSPSLVQFSCVALDSS 366
           F  H+  V  V  + +     S S D TVR + + T+           +V+    A +SS
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 289

Query: 367 ------------------GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
                             G F  +G +D   I +W +  G  L  L GH+  V  + F  
Sbjct: 290 YSSISEATGSETKKSGKPGPFLLSGSRDK-TIKMWDVSTGMCLMTLVGHDNWVRGVLFHS 348

Query: 409 TLTSTRLASASWDGTVRLWD 428
                 + S + D T+R+WD
Sbjct: 349 --GGKFILSCADDKTLRVWD 366


>AF208837-1|AAL34972.1|  410|Homo sapiens Miller-Dieker
           lissencephaly protein protein.
          Length = 410

 Score = 67.7 bits (158), Expect = 1e-10
 Identities = 64/259 (24%), Positives = 108/259 (41%), Gaps = 25/259 (9%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           + +    KLL +  +     L +      I T+   +H +SS+++ P GD I  A  +  
Sbjct: 156 ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD-K 214

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
            + +WE Q+   V    GH   +  +  + DG  + +   D  V+VW      C     E
Sbjct: 215 TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 274

Query: 311 HK--------------ATVSGVTCSANKK------FFVSSSLDGTVRCYDLTRYRNFRTL 350
           H+              +++S  T S  KK      F +S S D T++ +D++      TL
Sbjct: 275 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTL 334

Query: 351 TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTL 410
                     V   S G+F  +   D   + VW  K  + ++ L  HE  V+SL F    
Sbjct: 335 VGHDN-WVRGVLFHSGGKFILSCADDK-TLRVWDYKNKRCMKTLNAHEHFVTSLDFHK-- 390

Query: 411 TSTRLASASWDGTVRLWDC 429
           T+  + + S D TV++W+C
Sbjct: 391 TAPYVVTGSVDQTVKVWEC 409



 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 51/209 (24%), Positives = 95/209 (45%), Gaps = 8/209 (3%)

Query: 260 EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVT 319
           E+Y +   GH   +T + + P    +V+   D  +KVW+   G    T   H  +V  ++
Sbjct: 100 EKYALS--GHRSPVTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDIS 157

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFE 379
              + K   S S D T++ +D   +   RT+        S VA+  +G+   +  +D   
Sbjct: 158 FDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHD-HNVSSVAIMPNGDHIVSASRDK-T 215

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I +W ++ G  ++   GH   V  +   P    T +AS S D TVR+W    +E + E +
Sbjct: 216 IKMWEVQTGYCVKTFTGHREWVRMV--RPNQDGTLIASCSNDQTVRVWVVATKECKAE-L 272

Query: 440 RLNSDALQ-VAFRPDGEEIAVSTLDGNIT 467
           R +   ++ +++ P+    ++S   G+ T
Sbjct: 273 REHEHVVECISWAPESSYSSISEATGSET 301



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 60/260 (23%), Positives = 106/260 (40%), Gaps = 23/260 (8%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +T V +H    ++V+        + +    +   TL      +  IS    G  +A +C 
Sbjct: 111 VTRVIFHPVFSVMVSASEDATIKVWDYETGDFERTLKGHTDSVQDISFDHSGKLLA-SCS 169

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
               + +W++Q  + +    GH  +++ +A  P+G H+V+   D  +K+W    G+C  T
Sbjct: 170 ADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKT 229

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTSPSLVQFSCVALDSS 366
           F  H+  V  V  + +     S S D TVR + + T+           +V+    A +SS
Sbjct: 230 FTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELREHEHVVECISWAPESS 289

Query: 367 ------------------GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
                             G F  +G +D   I +W +  G  L  L GH+  V  + F  
Sbjct: 290 YSSISEATGSETKKSGKPGPFLLSGSRDK-TIKMWDVSTGMCLMTLVGHDNWVRGVLFHS 348

Query: 409 TLTSTRLASASWDGTVRLWD 428
                 + S + D T+R+WD
Sbjct: 349 --GGKFILSCADDKTLRVWD 366


>AK074217-1|BAB85020.1|  506|Homo sapiens protein ( Homo sapiens
           cDNA FLJ23637 fis, clone CAS09287. ).
          Length = 506

 Score = 67.3 bits (157), Expect = 2e-10
 Identities = 56/200 (28%), Positives = 89/200 (44%), Gaps = 9/200 (4%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATV-SGVTCSANKK 325
           +GH+  +  +  + D  HVV+G  D  VK+W+  N    +TF EH   V  G     N  
Sbjct: 119 EGHTKAVHTVDSTADKYHVVSGADDYTVKLWDIPNSKEILTFKEHSDYVRCGCASKLNPD 178

Query: 326 FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWS- 384
            F++ S D TV+ +D     +  ++     V+ S +   S G   +AGG+    + VW  
Sbjct: 179 LFITGSYDHTVKMFDARTSESVLSVEHGQPVE-SVLLFPSGGLLVSAGGR---YVKVWDM 234

Query: 385 IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSD 444
           +K G+LL  L  H   V+ L  S   +  RL S S D  V+++     +V        + 
Sbjct: 235 LKGGQLLVSLKNHHKTVTCLCLSS--SGQRLLSGSLDRKVKVYSTTSYKV-VHSFDYAAS 291

Query: 445 ALQVAFRPDGEEIAVSTLDG 464
            L +A   + E I V   +G
Sbjct: 292 ILSLALAHEDETIVVGMTNG 311



 Score = 37.5 bits (83), Expect = 0.17
 Identities = 17/49 (34%), Positives = 29/49 (59%), Gaps = 1/49 (2%)

Query: 254 VWEW-QSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTN 301
           VW+  +  Q ++  + H   +TCL  S  G  +++G  D KVKV++TT+
Sbjct: 231 VWDMLKGGQLLVSLKNHHKTVTCLCLSSSGQRLLSGSLDRKVKVYSTTS 279


>BC021110-1|AAH21110.1|  421|Homo sapiens WD repeat and SOCS
           box-containing 1 protein.
          Length = 421

 Score = 66.9 bits (156), Expect = 2e-10
 Identities = 60/241 (24%), Positives = 101/241 (41%), Gaps = 13/241 (5%)

Query: 192 QYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ 251
           Q H+  KL+        F LH   +V    +L +          + P + I   C +I  
Sbjct: 53  QGHRTVKLVPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHI-IDCGDI-- 109

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTC--LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             VW       V ++Q   +++      +  D L + TG  +G++K+W+   G   +   
Sbjct: 110 --VWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLV 167

Query: 310 EHKATVSGVTCSAN-KKFFVSSSLDGTVRCYDLTRYRN-FRTLTSPSLVQFSCVALDSSG 367
           +H   V  +T + +     VS+S D T+R +DL    N  + L       +SC     S 
Sbjct: 168 DHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS 227

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
             C+ G      +F+W++    ++  L GH   V +  FSP      LA+AS+D  V +W
Sbjct: 228 MLCSVGASKA--VFLWNMDKYTMIRKLEGHHHDVVACDFSP--DGALLATASYDTRVYIW 283

Query: 428 D 428
           D
Sbjct: 284 D 284



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 56/238 (23%), Positives = 98/238 (41%), Gaps = 23/238 (9%)

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG-LHVVTGGFDGKVKVWNTTN-GFCF 305
           N G++ +W+  + + ++    H+  +  L ++PDG L +V+   D  ++VW+  + G   
Sbjct: 148 NNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMM 207

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
                H+  V     S +     S      V  +++ +Y   R L        +C     
Sbjct: 208 KVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVAC-DFSP 266

Query: 366 SGEFCAAGGQDVFEIFVWS-------IKFGKLLE------VLGGHEAPVSSLAFSPTLTS 412
            G   A    D   +++W        ++FG L          G ++  V S++FS     
Sbjct: 267 DGALLATASYDT-RVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHD--G 323

Query: 413 TRLASASWDGTVRLWDCI-DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
             +AS + D  VR W    D  VQ  P+   S+ L  AF  DG  +A  T DG++ F+
Sbjct: 324 LHVASLADDKMVRFWRIDEDYPVQVAPL---SNGLCCAFSTDGSVLAAGTHDGSVYFW 378



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 16/181 (8%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVM--KQQGHSLDM 273
           D N++  L   ++ + S + SP    +   C       V+ W  ++Y M  K +GH  D+
Sbjct: 203 DGNMMKVLRGHQNWVYSCAFSPDSSML---CSVGASKAVFLWNMDKYTMIRKLEGHHHDV 259

Query: 274 TCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF-HEHKATVSGVTCSANKKFF--VSS 330
               +SPDG  + T  +D +V +W+  NG   + F H            AN ++   VS 
Sbjct: 260 VACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSF 319

Query: 331 SLDGT-VRCYDLTRYRNFRTLTSPSLVQFS------CVALDSSGEFCAAGGQDVFEIFVW 383
           S DG  V      +   F  +     VQ +      C A  + G   AAG  D   ++ W
Sbjct: 320 SHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHD-GSVYFW 378

Query: 384 S 384
           +
Sbjct: 379 A 379



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 5/92 (5%)

Query: 382 VWSIKF-GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
           VW +K  G +++VL GH+  V S AFSP   S+ L S      V LW+ +D+      + 
Sbjct: 197 VWDLKDDGNMMKVLRGHQNWVYSCAFSPD--SSMLCSVGASKAVFLWN-MDKYTMIRKLE 253

Query: 441 -LNSDALQVAFRPDGEEIAVSTLDGNITFFEP 471
             + D +   F PDG  +A ++ D  +  ++P
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIWDP 285


>AF112205-1|AAF17193.1|  421|Homo sapiens WSB-1 protein protein.
          Length = 421

 Score = 66.9 bits (156), Expect = 2e-10
 Identities = 60/241 (24%), Positives = 101/241 (41%), Gaps = 13/241 (5%)

Query: 192 QYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ 251
           Q H+  KL+        F LH   +V    +L +          + P + I   C +I  
Sbjct: 53  QGHRTVKLVPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHI-IDCGDI-- 109

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTC--LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             VW       V ++Q   +++      +  D L + TG  +G++K+W+   G   +   
Sbjct: 110 --VWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLV 167

Query: 310 EHKATVSGVTCSAN-KKFFVSSSLDGTVRCYDLTRYRN-FRTLTSPSLVQFSCVALDSSG 367
           +H   V  +T + +     VS+S D T+R +DL    N  + L       +SC     S 
Sbjct: 168 DHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS 227

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
             C+ G      +F+W++    ++  L GH   V +  FSP      LA+AS+D  V +W
Sbjct: 228 MLCSVGASKA--VFLWNMDKYTMIRKLEGHHHDVVACDFSP--DGALLATASYDTRVYIW 283

Query: 428 D 428
           D
Sbjct: 284 D 284



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 56/238 (23%), Positives = 98/238 (41%), Gaps = 23/238 (9%)

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG-LHVVTGGFDGKVKVWNTTN-GFCF 305
           N G++ +W+  + + ++    H+  +  L ++PDG L +V+   D  ++VW+  + G   
Sbjct: 148 NNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMM 207

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
                H+  V     S +     S      V  +++ +Y   R L        +C     
Sbjct: 208 KVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVAC-DFSP 266

Query: 366 SGEFCAAGGQDVFEIFVWS-------IKFGKLLE------VLGGHEAPVSSLAFSPTLTS 412
            G   A    D   +++W        ++FG L          G ++  V S++FS     
Sbjct: 267 DGALLATASYDT-RVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHD--G 323

Query: 413 TRLASASWDGTVRLWDCI-DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
             +AS + D  VR W    D  VQ  P+   S+ L  AF  DG  +A  T DG++ F+
Sbjct: 324 LHVASLADDKMVRFWRIDEDYPVQVAPL---SNGLCCAFSTDGSVLAAGTHDGSVYFW 378



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 16/181 (8%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVM--KQQGHSLDM 273
           D N++  L   ++ + S + SP    +   C       V+ W  ++Y M  K +GH  D+
Sbjct: 203 DGNMMKVLRGHQNWVYSCAFSPDSSML---CSVGASKAVFLWNMDKYTMIRKLEGHHHDV 259

Query: 274 TCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF-HEHKATVSGVTCSANKKFF--VSS 330
               +SPDG  + T  +D +V +W+  NG   + F H            AN ++   VS 
Sbjct: 260 VACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSF 319

Query: 331 SLDGT-VRCYDLTRYRNFRTLTSPSLVQFS------CVALDSSGEFCAAGGQDVFEIFVW 383
           S DG  V      +   F  +     VQ +      C A  + G   AAG  D   ++ W
Sbjct: 320 SHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHD-GSVYFW 378

Query: 384 S 384
           +
Sbjct: 379 A 379



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 5/92 (5%)

Query: 382 VWSIKF-GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
           VW +K  G +++VL GH+  V S AFSP   S+ L S      V LW+ +D+      + 
Sbjct: 197 VWDLKDDGNMMKVLRGHQNWVYSCAFSPD--SSMLCSVGASKAVFLWN-MDKYTMIRKLE 253

Query: 441 -LNSDALQVAFRPDGEEIAVSTLDGNITFFEP 471
             + D +   F PDG  +A ++ D  +  ++P
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIWDP 285


>AF072880-1|AAD28808.1|  421|Homo sapiens SOCS box-containing WD
           protein SWiP-1 protein.
          Length = 421

 Score = 66.9 bits (156), Expect = 2e-10
 Identities = 60/241 (24%), Positives = 101/241 (41%), Gaps = 13/241 (5%)

Query: 192 QYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ 251
           Q H+  KL+        F LH   +V    +L +          + P + I   C +I  
Sbjct: 53  QGHRTVKLVPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHI-IDCGDI-- 109

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTC--LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             VW       V ++Q   +++      +  D L + TG  +G++K+W+   G   +   
Sbjct: 110 --VWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLV 167

Query: 310 EHKATVSGVTCSAN-KKFFVSSSLDGTVRCYDLTRYRN-FRTLTSPSLVQFSCVALDSSG 367
           +H   V  +T + +     VS+S D T+R +DL    N  + L       +SC     S 
Sbjct: 168 DHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS 227

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
             C+ G      +F+W++    ++  L GH   V +  FSP      LA+AS+D  V +W
Sbjct: 228 MLCSVGASKA--VFLWNMDKYTMIRKLEGHHHDVVACDFSP--DGALLATASYDTRVYIW 283

Query: 428 D 428
           D
Sbjct: 284 D 284



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 56/238 (23%), Positives = 98/238 (41%), Gaps = 23/238 (9%)

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG-LHVVTGGFDGKVKVWNTTN-GFCF 305
           N G++ +W+  + + ++    H+  +  L ++PDG L +V+   D  ++VW+  + G   
Sbjct: 148 NNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMM 207

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
                H+  V     S +     S      V  +++ +Y   R L        +C     
Sbjct: 208 KVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVAC-DFSP 266

Query: 366 SGEFCAAGGQDVFEIFVWS-------IKFGKLLE------VLGGHEAPVSSLAFSPTLTS 412
            G   A    D   +++W        ++FG L          G ++  V S++FS     
Sbjct: 267 DGALLATASYDT-RVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHD--G 323

Query: 413 TRLASASWDGTVRLWDCI-DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
             +AS + D  VR W    D  VQ  P+   S+ L  AF  DG  +A  T DG++ F+
Sbjct: 324 LHVASLADDKMVRFWRIDEDYPVQVAPL---SNGLCCAFSTDGSVLAAGTHDGSVYFW 378



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 16/181 (8%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVM--KQQGHSLDM 273
           D N++  L   ++ + S + SP    +   C       V+ W  ++Y M  K +GH  D+
Sbjct: 203 DGNMMKVLRGHQNWVYSCAFSPDSSML---CSVGASKAVFLWNMDKYTMIRKLEGHHHDV 259

Query: 274 TCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF-HEHKATVSGVTCSANKKFF--VSS 330
               +SPDG  + T  +D +V +W+  NG   + F H            AN ++   VS 
Sbjct: 260 VACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSF 319

Query: 331 SLDGT-VRCYDLTRYRNFRTLTSPSLVQFS------CVALDSSGEFCAAGGQDVFEIFVW 383
           S DG  V      +   F  +     VQ +      C A  + G   AAG  D   ++ W
Sbjct: 320 SHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHD-GSVYFW 378

Query: 384 S 384
           +
Sbjct: 379 A 379



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 5/92 (5%)

Query: 382 VWSIKF-GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
           VW +K  G +++VL GH+  V S AFSP   S+ L S      V LW+ +D+      + 
Sbjct: 197 VWDLKDDGNMMKVLRGHQNWVYSCAFSPD--SSMLCSVGASKAVFLWN-MDKYTMIRKLE 253

Query: 441 -LNSDALQVAFRPDGEEIAVSTLDGNITFFEP 471
             + D +   F PDG  +A ++ D  +  ++P
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIWDP 285


>AF069313-1|AAD20954.2|  421|Homo sapiens WSB1 protein protein.
          Length = 421

 Score = 66.9 bits (156), Expect = 2e-10
 Identities = 60/241 (24%), Positives = 101/241 (41%), Gaps = 13/241 (5%)

Query: 192 QYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ 251
           Q H+  KL+        F LH   +V    +L +          + P + I   C +I  
Sbjct: 53  QGHRTVKLVPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHI-IDCGDI-- 109

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTC--LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             VW       V ++Q   +++      +  D L + TG  +G++K+W+   G   +   
Sbjct: 110 --VWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLV 167

Query: 310 EHKATVSGVTCSAN-KKFFVSSSLDGTVRCYDLTRYRN-FRTLTSPSLVQFSCVALDSSG 367
           +H   V  +T + +     VS+S D T+R +DL    N  + L       +SC     S 
Sbjct: 168 DHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS 227

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
             C+ G      +F+W++    ++  L GH   V +  FSP      LA+AS+D  V +W
Sbjct: 228 MLCSVGASKA--VFLWNMDKYTMIRKLEGHHHDVVACDFSP--DGALLATASYDTRVYIW 283

Query: 428 D 428
           D
Sbjct: 284 D 284



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 56/238 (23%), Positives = 98/238 (41%), Gaps = 23/238 (9%)

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG-LHVVTGGFDGKVKVWNTTN-GFCF 305
           N G++ +W+  + + ++    H+  +  L ++PDG L +V+   D  ++VW+  + G   
Sbjct: 148 NNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMM 207

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
                H+  V     S +     S      V  +++ +Y   R L        +C     
Sbjct: 208 KVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVAC-DFSP 266

Query: 366 SGEFCAAGGQDVFEIFVWS-------IKFGKLLE------VLGGHEAPVSSLAFSPTLTS 412
            G   A    D   +++W        ++FG L          G ++  V S++FS     
Sbjct: 267 DGALLATASYDT-RVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHD--G 323

Query: 413 TRLASASWDGTVRLWDCI-DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
             +AS + D  VR W    D  VQ  P+   S+ L  AF  DG  +A  T DG++ F+
Sbjct: 324 LHVASLADDKMVRFWRIDEDYPVQVAPL---SNGLCCAFSTDGSVLAAGTHDGSVYFW 378



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 16/181 (8%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVM--KQQGHSLDM 273
           D N++  L   ++ + S + SP    +   C       V+ W  ++Y M  K +GH  D+
Sbjct: 203 DGNMMKVLRGHQNWVYSCAFSPDSSML---CSVGASKAVFLWNMDKYTMIRKLEGHHHDV 259

Query: 274 TCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF-HEHKATVSGVTCSANKKFF--VSS 330
               +SPDG  + T  +D +V +W+  NG   + F H            AN ++   VS 
Sbjct: 260 VACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSF 319

Query: 331 SLDGT-VRCYDLTRYRNFRTLTSPSLVQFS------CVALDSSGEFCAAGGQDVFEIFVW 383
           S DG  V      +   F  +     VQ +      C A  + G   AAG  D   ++ W
Sbjct: 320 SHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHD-GSVYFW 378

Query: 384 S 384
           +
Sbjct: 379 A 379



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 5/92 (5%)

Query: 382 VWSIKF-GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
           VW +K  G +++VL GH+  V S AFSP   S+ L S      V LW+ +D+      + 
Sbjct: 197 VWDLKDDGNMMKVLRGHQNWVYSCAFSPD--SSMLCSVGASKAVFLWN-MDKYTMIRKLE 253

Query: 441 -LNSDALQVAFRPDGEEIAVSTLDGNITFFEP 471
             + D +   F PDG  +A ++ D  +  ++P
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIWDP 285


>Y12781-1|CAA73319.1|  577|Homo sapiens transducin (beta) like 1
           protein protein.
          Length = 577

 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/203 (27%), Positives = 91/203 (44%), Gaps = 12/203 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G ++++ G D    +W+   G     F  H A    V    N   F 
Sbjct: 328 HKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNTTFA 386

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L   R  +T    +  + + +  D SG   A+   D+  + +WS+K  
Sbjct: 387 SCSTDMCIHVCRLGCDRPVKTFQGHTN-EVNAIKWDPSGMLLASCSDDM-TLKIWSMKQE 444

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT  +T        LASAS+D TVRLWD I+R V    +  
Sbjct: 445 VCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD-IERGVCTHTLTK 503

Query: 442 NSDAL-QVAFRPDGEEIAVSTLD 463
           + + +  VAF PDG+ +A  + D
Sbjct: 504 HQEPVYSVAFSPDGKYLASGSFD 526



 Score = 48.4 bits (110), Expect = 9e-05
 Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 11/139 (7%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGV-------- 318
           QGH+ ++  + + P G+ + +   D  +K+W+     C      H   +  +        
Sbjct: 409 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPA 468

Query: 319 TCSANKKFFV-SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDV 377
           T + N    + S+S D TVR +D+ R     TLT      +S VA    G++ A+G  D 
Sbjct: 469 TSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYS-VAFSPDGKYLASGSFDK 527

Query: 378 FEIFVWSIKFGKLLEVLGG 396
             + +W+ + G L+    G
Sbjct: 528 C-VHIWNTQSGNLVHSYRG 545



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 62/291 (21%), Positives = 123/291 (42%), Gaps = 31/291 (10%)

Query: 261 QYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
           ++ +++ GH +    D+T L ++ +G  + TG +DG  ++W T +G    T  +HK  + 
Sbjct: 275 RHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIF 333

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            +  +    + +S+ +D T   +D       + F   ++P+L       +D       A 
Sbjct: 334 ALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPAL------DVDWQNNTTFAS 387

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDRE 433
                 I V  +   + ++   GH   V+++ + P  +   LAS S D T+++W  + +E
Sbjct: 388 CSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS-MKQE 444

Query: 434 VQCEPIRL-NSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSGRAE 492
           V    ++  N +   + + P G   A S  + NI     S      S     D+  G   
Sbjct: 445 VCIHDLQAHNKEIYTIKWSPTGP--ATSNPNSNIMLASAS----FDSTVRLWDIERG--- 495

Query: 493 TDLVTPQTLLK-TKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKF 542
              V   TL K  +   ++ +S DG  +  G   K V +++ +   L+  +
Sbjct: 496 ---VCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSY 543



 Score = 42.3 bits (95), Expect = 0.006
 Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++ A+++     LL +        +  M     IH L      I +I  SP G   A + 
Sbjct: 414 EVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGP--ATSN 471

Query: 247 PNIGQLL--------VWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKV 296
           PN   +L        V  W  E+ V       H   +  +A+SPDG ++ +G FD  V +
Sbjct: 472 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHI 531

Query: 297 WNTTNGFCFVTFHEHKAT--VSGVTCSANKKFFVSSSLDGTVRCYDLTR 343
           WNT +G      H ++ T  +  V  +A      +S+ DG+V   DL +
Sbjct: 532 WNTQSG---NLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 577



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           +VT LDW++   LLA GS D   +I T +   N+   +L  H   I  + + RK   +++
Sbjct: 290 DVTSLDWNTNGTLLATGSYDGFARIWTED--GNLAS-TLGQHKGPIFALKWNRKGNYILS 346

Query: 86  VSRNGQLCLWEA 97
              +    +W+A
Sbjct: 347 AGVDKTTIIWDA 358



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           VL GHE+ V   A++P   S  LAS S D T R+W+
Sbjct: 227 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWN 260


>BC052304-1|AAH52304.1|  577|Homo sapiens transducin (beta)-like
           1X-linked protein.
          Length = 577

 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/203 (27%), Positives = 91/203 (44%), Gaps = 12/203 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G ++++ G D    +W+   G     F  H A    V    N   F 
Sbjct: 328 HKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNTTFA 386

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L   R  +T    +  + + +  D SG   A+   D+  + +WS+K  
Sbjct: 387 SCSTDMCIHVCRLGCDRPVKTFQGHTN-EVNAIKWDPSGMLLASCSDDM-TLKIWSMKQE 444

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT  +T        LASAS+D TVRLWD I+R V    +  
Sbjct: 445 VCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD-IERGVCTHTLTK 503

Query: 442 NSDAL-QVAFRPDGEEIAVSTLD 463
           + + +  VAF PDG+ +A  + D
Sbjct: 504 HQEPVYSVAFSPDGKYLASGSFD 526



 Score = 48.4 bits (110), Expect = 9e-05
 Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 11/139 (7%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGV-------- 318
           QGH+ ++  + + P G+ + +   D  +K+W+     C      H   +  +        
Sbjct: 409 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPA 468

Query: 319 TCSANKKFFV-SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDV 377
           T + N    + S+S D TVR +D+ R     TLT      +S VA    G++ A+G  D 
Sbjct: 469 TSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYS-VAFSPDGKYLASGSFDK 527

Query: 378 FEIFVWSIKFGKLLEVLGG 396
             + +W+ + G L+    G
Sbjct: 528 C-VHIWNTQSGNLVHSYRG 545



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 62/291 (21%), Positives = 123/291 (42%), Gaps = 31/291 (10%)

Query: 261 QYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
           ++ +++ GH +    D+T L ++ +G  + TG +DG  ++W T +G    T  +HK  + 
Sbjct: 275 RHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIF 333

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            +  +    + +S+ +D T   +D       + F   ++P+L       +D       A 
Sbjct: 334 ALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPAL------DVDWQNNTTFAS 387

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDRE 433
                 I V  +   + ++   GH   V+++ + P  +   LAS S D T+++W  + +E
Sbjct: 388 CSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS-MKQE 444

Query: 434 VQCEPIRL-NSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSGRAE 492
           V    ++  N +   + + P G   A S  + NI     S      S     D+  G   
Sbjct: 445 VCIHDLQAHNKEIYTIKWSPTGP--ATSNPNSNIMLASAS----FDSTVRLWDIERG--- 495

Query: 493 TDLVTPQTLLK-TKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKF 542
              V   TL K  +   ++ +S DG  +  G   K V +++ +   L+  +
Sbjct: 496 ---VCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSY 543



 Score = 42.3 bits (95), Expect = 0.006
 Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++ A+++     LL +        +  M     IH L      I +I  SP G   A + 
Sbjct: 414 EVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGP--ATSN 471

Query: 247 PNIGQLL--------VWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKV 296
           PN   +L        V  W  E+ V       H   +  +A+SPDG ++ +G FD  V +
Sbjct: 472 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHI 531

Query: 297 WNTTNGFCFVTFHEHKAT--VSGVTCSANKKFFVSSSLDGTVRCYDLTR 343
           WNT +G      H ++ T  +  V  +A      +S+ DG+V   DL +
Sbjct: 532 WNTQSG---NLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 577



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           +VT LDW++   LLA GS D   +I T +   N+   +L  H   I  + + RK   +++
Sbjct: 290 DVTSLDWNTNGTLLATGSYDGFARIWTED--GNLAS-TLGQHKGPIFALKWNRKGNYILS 346

Query: 86  VSRNGQLCLWEA 97
              +    +W+A
Sbjct: 347 AGVDKTTIIWDA 358



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           VL GHE+ V   A++P   S  LAS S D T R+W+
Sbjct: 227 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWN 260


>BC032708-1|AAH32708.1|  526|Homo sapiens TBL1X protein protein.
          Length = 526

 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/203 (27%), Positives = 91/203 (44%), Gaps = 12/203 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G ++++ G D    +W+   G     F  H A    V    N   F 
Sbjct: 277 HKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNTTFA 335

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L   R  +T    +  + + +  D SG   A+   D+  + +WS+K  
Sbjct: 336 SCSTDMCIHVCRLGCDRPVKTFQGHTN-EVNAIKWDPSGMLLASCSDDM-TLKIWSMKQE 393

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT  +T        LASAS+D TVRLWD I+R V    +  
Sbjct: 394 VCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD-IERGVCTHTLTK 452

Query: 442 NSDAL-QVAFRPDGEEIAVSTLD 463
           + + +  VAF PDG+ +A  + D
Sbjct: 453 HQEPVYSVAFSPDGKYLASGSFD 475



 Score = 48.4 bits (110), Expect = 9e-05
 Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 11/139 (7%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGV-------- 318
           QGH+ ++  + + P G+ + +   D  +K+W+     C      H   +  +        
Sbjct: 358 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPA 417

Query: 319 TCSANKKFFV-SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDV 377
           T + N    + S+S D TVR +D+ R     TLT      +S VA    G++ A+G  D 
Sbjct: 418 TSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYS-VAFSPDGKYLASGSFDK 476

Query: 378 FEIFVWSIKFGKLLEVLGG 396
             + +W+ + G L+    G
Sbjct: 477 C-VHIWNTQSGNLVHSYRG 494



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 62/291 (21%), Positives = 123/291 (42%), Gaps = 31/291 (10%)

Query: 261 QYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
           ++ +++ GH +    D+T L ++ +G  + TG +DG  ++W T +G    T  +HK  + 
Sbjct: 224 RHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIF 282

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            +  +    + +S+ +D T   +D       + F   ++P+L       +D       A 
Sbjct: 283 ALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPAL------DVDWQNNTTFAS 336

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDRE 433
                 I V  +   + ++   GH   V+++ + P  +   LAS S D T+++W  + +E
Sbjct: 337 CSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS-MKQE 393

Query: 434 VQCEPIRL-NSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSGRAE 492
           V    ++  N +   + + P G   A S  + NI     S      S     D+  G   
Sbjct: 394 VCIHDLQAHNKEIYTIKWSPTGP--ATSNPNSNIMLASAS----FDSTVRLWDIERG--- 444

Query: 493 TDLVTPQTLLK-TKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKF 542
              V   TL K  +   ++ +S DG  +  G   K V +++ +   L+  +
Sbjct: 445 ---VCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSY 492



 Score = 42.3 bits (95), Expect = 0.006
 Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++ A+++     LL +        +  M     IH L      I +I  SP G   A + 
Sbjct: 363 EVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGP--ATSN 420

Query: 247 PNIGQLL--------VWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKV 296
           PN   +L        V  W  E+ V       H   +  +A+SPDG ++ +G FD  V +
Sbjct: 421 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHI 480

Query: 297 WNTTNGFCFVTFHEHKAT--VSGVTCSANKKFFVSSSLDGTVRCYDLTR 343
           WNT +G      H ++ T  +  V  +A      +S+ DG+V   DL +
Sbjct: 481 WNTQSG---NLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 526



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           +VT LDW++   LLA GS D   +I T +   N+   +L  H   I  + + RK   +++
Sbjct: 239 DVTSLDWNTNGTLLATGSYDGFARIWTED--GNLAS-TLGQHKGPIFALKWNRKGNYILS 295

Query: 86  VSRNGQLCLWEA 97
              +    +W+A
Sbjct: 296 AGVDKTTIIWDA 307



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           VL GHE+ V   A++P   S  LAS S D T R+W+
Sbjct: 176 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWN 209


>AY336089-1|AAR24619.1|  271|Homo sapiens proliferation-inducing
           gene 21 protein.
          Length = 271

 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 48/165 (29%), Positives = 79/165 (47%), Gaps = 11/165 (6%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE--HKATVSGVTCSANKK 325
           GH+ D+  +A+S D   +V+G  D  +K+WNT  G C  T  +  H   VS V  S N  
Sbjct: 57  GHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTL-GVCKYTVQDESHSEWVSCVRFSPNSS 115

Query: 326 --FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVW 383
               VS   D  V+ ++L   +  +T         + V +   G  CA+GG+D  +  +W
Sbjct: 116 NPIIVSCGWDKLVKVWNLANCK-LKTNHIGHTGYLNTVTVSPDGSLCASGGKD-GQAMLW 173

Query: 384 SIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
            +  GK L  L G +  +++L FSP   +     A+   ++++WD
Sbjct: 174 DLNEGKHLYTLDGGDI-INALCFSP---NRYWLCAATGPSIKIWD 214



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 32/122 (26%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC- 246
           L  V    +  L  +G   G   L ++ +   ++TL   +  I+++  SP   W+  A  
Sbjct: 149 LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGDI-INALCFSPNRYWLCAATG 207

Query: 247 PNI------GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTT 300
           P+I      G+++V E + E      +      T LA+S DG  +  G  D  V+VW  T
Sbjct: 208 PSIKIWDLEGKIIVDELKQEVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVWQVT 267

Query: 301 NG 302
            G
Sbjct: 268 IG 269



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 31/155 (20%), Positives = 65/155 (41%), Gaps = 6/155 (3%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHR--ISSISVSP-PGDWIAFAC 246
           +V +  +N+ +V+G       L     V   +T+    H   +S +  SP   + I  +C
Sbjct: 64  SVAFSSDNRQIVSGSRDKTIKLWNTLGV-CKYTVQDESHSEWVSCVRFSPNSSNPIIVSC 122

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
                + VW   + +      GH+  +  +  SPDG    +GG DG+  +W+   G    
Sbjct: 123 GWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLY 182

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
           T       +    C +  ++++ ++   +++ +DL
Sbjct: 183 TL--DGGDIINALCFSPNRYWLCAATGPSIKIWDL 215



 Score = 35.5 bits (78), Expect = 0.69
 Identities = 20/86 (23%), Positives = 38/86 (44%)

Query: 397 HEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEE 456
           H   VS + FSP  ++  + S  WD  V++W+  + +++   I        V   PDG  
Sbjct: 101 HSEWVSCVRFSPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGYLNTVTVSPDGSL 160

Query: 457 IAVSTLDGNITFFEPSTCEQTGSVEG 482
            A    DG    ++ +  +   +++G
Sbjct: 161 CASGGKDGQAMLWDLNEGKHLYTLDG 186


>AF106683-1|AAD43036.1|  421|Homo sapiens WSB-1 protein.
          Length = 421

 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 60/241 (24%), Positives = 100/241 (41%), Gaps = 13/241 (5%)

Query: 192 QYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ 251
           Q H+  KL+        F LH   +V    +L +          + P + I   C +I  
Sbjct: 53  QGHRTVKLVPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHI-IDCGDI-- 109

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTC--LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             VW       V ++Q   +++      +  D L + TG  +G++K+W+   G   +   
Sbjct: 110 --VWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLV 167

Query: 310 EHKATVSGVTCSAN-KKFFVSSSLDGTVRCYDLTRYRN-FRTLTSPSLVQFSCVALDSSG 367
           +H   V  +T + +     VS+S D T+R +DL    N  + L       +SC     S 
Sbjct: 168 DHTEVVRDLTLAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS 227

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
             C  G      +F+W++    ++  L GH   V +  FSP      LA+AS+D  V +W
Sbjct: 228 MLCPVGASKA--VFLWNMDKYTMIRKLEGHHHDVVACDFSP--DGALLATASYDTRVYIW 283

Query: 428 D 428
           D
Sbjct: 284 D 284



 Score = 50.0 bits (114), Expect = 3e-05
 Identities = 47/181 (25%), Positives = 75/181 (41%), Gaps = 16/181 (8%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVM--KQQGHSLDM 273
           D N++  L   ++ + S + SP    +   CP      V+ W  ++Y M  K +GH  D+
Sbjct: 203 DGNMMKVLRGHQNWVYSCAFSPDSSML---CPVGASKAVFLWNMDKYTMIRKLEGHHHDV 259

Query: 274 TCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF-HEHKATVSGVTCSANKKFF--VSS 330
               +SPDG  + T  +D +V +W+  NG   + F H            AN ++   VS 
Sbjct: 260 VACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSF 319

Query: 331 SLDGT-VRCYDLTRYRNFRTLTSPSLVQFS------CVALDSSGEFCAAGGQDVFEIFVW 383
           S DG  V      +   F  +     VQ +      C A  + G   AAG  D   ++ W
Sbjct: 320 SHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHD-GSVYFW 378

Query: 384 S 384
           +
Sbjct: 379 A 379



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 55/238 (23%), Positives = 96/238 (40%), Gaps = 23/238 (9%)

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG-LHVVTGGFDGKVKVWNTTN-GFCF 305
           N G++ +W+  + + ++    H+  +  L  +PDG L +V+   D  ++VW+  + G   
Sbjct: 148 NNGRIKIWDVYTGKLLLNLVDHTEVVRDLTLAPDGSLILVSASRDKTLRVWDLKDDGNMM 207

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
                H+  V     S +            V  +++ +Y   R L        +C     
Sbjct: 208 KVLRGHQNWVYSCAFSPDSSMLCPVGASKAVFLWNMDKYTMIRKLEGHHHDVVAC-DFSP 266

Query: 366 SGEFCAAGGQDVFEIFVWS-------IKFGKLLE------VLGGHEAPVSSLAFSPTLTS 412
            G   A    D   +++W        ++FG L          G ++  V S++FS     
Sbjct: 267 DGALLATASYDT-RVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHD--G 323

Query: 413 TRLASASWDGTVRLWDCI-DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
             +AS + D  VR W    D  VQ  P+   S+ L  AF  DG  +A  T DG++ F+
Sbjct: 324 LHVASLADDKMVRFWRIDEDYPVQVAPL---SNGLCCAFSTDGSVLAAGTHDGSVYFW 378



 Score = 41.5 bits (93), Expect = 0.011
 Identities = 28/92 (30%), Positives = 46/92 (50%), Gaps = 5/92 (5%)

Query: 382 VWSIKF-GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
           VW +K  G +++VL GH+  V S AFSP   S+ L        V LW+ +D+      + 
Sbjct: 197 VWDLKDDGNMMKVLRGHQNWVYSCAFSPD--SSMLCPVGASKAVFLWN-MDKYTMIRKLE 253

Query: 441 -LNSDALQVAFRPDGEEIAVSTLDGNITFFEP 471
             + D +   F PDG  +A ++ D  +  ++P
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIWDP 285


>AB209608-1|BAD92845.1|  540|Homo sapiens transducin beta-like 1X
           variant protein.
          Length = 540

 Score = 66.5 bits (155), Expect = 3e-10
 Identities = 56/203 (27%), Positives = 91/203 (44%), Gaps = 12/203 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G ++++ G D    +W+   G     F  H A    V    N   F 
Sbjct: 291 HKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNTTFA 349

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L   R  +T    +  + + +  D SG   A+   D+  + +WS+K  
Sbjct: 350 SCSTDMCIHVCRLGCDRPVKTFQGHTN-EVNAIKWDPSGMLLASCSDDM-TLKIWSMKQE 407

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT  +T        LASAS+D TVRLWD I+R V    +  
Sbjct: 408 VCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDSTVRLWD-IERGVCTHTLTK 466

Query: 442 NSDAL-QVAFRPDGEEIAVSTLD 463
           + + +  VAF PDG+ +A  + D
Sbjct: 467 HQEPVYSVAFSPDGKYLASGSFD 489



 Score = 48.4 bits (110), Expect = 9e-05
 Identities = 34/139 (24%), Positives = 61/139 (43%), Gaps = 11/139 (7%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGV-------- 318
           QGH+ ++  + + P G+ + +   D  +K+W+     C      H   +  +        
Sbjct: 372 QGHTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPA 431

Query: 319 TCSANKKFFV-SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDV 377
           T + N    + S+S D TVR +D+ R     TLT      +S VA    G++ A+G  D 
Sbjct: 432 TSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYS-VAFSPDGKYLASGSFDK 490

Query: 378 FEIFVWSIKFGKLLEVLGG 396
             + +W+ + G L+    G
Sbjct: 491 C-VHIWNTQSGNLVHSYRG 508



 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 62/291 (21%), Positives = 123/291 (42%), Gaps = 31/291 (10%)

Query: 261 QYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
           ++ +++ GH +    D+T L ++ +G  + TG +DG  ++W T +G    T  +HK  + 
Sbjct: 238 RHCIREGGHDVPSNKDVTSLDWNTNGTLLATGSYDGFARIW-TEDGNLASTLGQHKGPIF 296

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            +  +    + +S+ +D T   +D       + F   ++P+L       +D       A 
Sbjct: 297 ALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPAL------DVDWQNNTTFAS 350

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDRE 433
                 I V  +   + ++   GH   V+++ + P  +   LAS S D T+++W  + +E
Sbjct: 351 CSTDMCIHVCRLGCDRPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS-MKQE 407

Query: 434 VQCEPIRL-NSDALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSGRAE 492
           V    ++  N +   + + P G   A S  + NI     S      S     D+  G   
Sbjct: 408 VCIHDLQAHNKEIYTIKWSPTGP--ATSNPNSNIMLASAS----FDSTVRLWDIERG--- 458

Query: 493 TDLVTPQTLLK-TKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKF 542
              V   TL K  +   ++ +S DG  +  G   K V +++ +   L+  +
Sbjct: 459 ---VCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHIWNTQSGNLVHSY 506



 Score = 42.3 bits (95), Expect = 0.006
 Identities = 44/169 (26%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++ A+++     LL +        +  M     IH L      I +I  SP G   A + 
Sbjct: 377 EVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGP--ATSN 434

Query: 247 PNIGQLL--------VWEWQSEQYVMKQQ--GHSLDMTCLAYSPDGLHVVTGGFDGKVKV 296
           PN   +L        V  W  E+ V       H   +  +A+SPDG ++ +G FD  V +
Sbjct: 435 PNSNIMLASASFDSTVRLWDIERGVCTHTLTKHQEPVYSVAFSPDGKYLASGSFDKCVHI 494

Query: 297 WNTTNGFCFVTFHEHKAT--VSGVTCSANKKFFVSSSLDGTVRCYDLTR 343
           WNT +G      H ++ T  +  V  +A      +S+ DG+V   DL +
Sbjct: 495 WNTQSG---NLVHSYRGTGGIFEVCWNARGDKVGASASDGSVCVLDLRK 540



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           +VT LDW++   LLA GS D   +I T +   N+   +L  H   I  + + RK   +++
Sbjct: 253 DVTSLDWNTNGTLLATGSYDGFARIWTED--GNLAS-TLGQHKGPIFALKWNRKGNYILS 309

Query: 86  VSRNGQLCLWEA 97
              +    +W+A
Sbjct: 310 AGVDKTTIIWDA 321



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           VL GHE+ V   A++P   S  LAS S D T R+W+
Sbjct: 190 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWN 223


>AK222501-1|BAD96221.1|  392|Homo sapiens hypothetical protein
           FLJ11848 variant protein.
          Length = 392

 Score = 66.1 bits (154), Expect = 4e-10
 Identities = 38/134 (28%), Positives = 63/134 (47%), Gaps = 6/134 (4%)

Query: 210 FLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGH 269
           FL      + IHT SI+      + +S  G  +  +    G + +W+  + +     +GH
Sbjct: 80  FLAPYTTFSRIHTKSIT-----CLDISSRGG-LGVSSSTDGTMKIWQASNGELRRVLEGH 133

Query: 270 SLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVS 329
             D+    + P GL V++GG D ++K+W+  +  C VTF  HK  +         +  VS
Sbjct: 134 VFDVNSCRFFPSGLVVLSGGMDAQLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVS 193

Query: 330 SSLDGTVRCYDLTR 343
           +S DGT R +D  R
Sbjct: 194 ASRDGTARLWDCGR 207



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 36/126 (28%), Positives = 55/126 (43%), Gaps = 5/126 (3%)

Query: 305 FVTFHE-HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           + TF   H  +++ +  S+     VSSS DGT++ +  +     R L        SC   
Sbjct: 84  YTTFSRIHTKSITCLDISSRGGLGVSSSTDGTMKIWQASNGELRRVLEGHVFDVNSC-RF 142

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
             SG    +GG D  ++ +WS +    +    GH+  +   A         + SAS DGT
Sbjct: 143 FPSGLVVLSGGMDA-QLKIWSAEDASCVVTFKGHKGGILDTAIVDR--GRNVVSASRDGT 199

Query: 424 VRLWDC 429
            RLWDC
Sbjct: 200 ARLWDC 205



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 17/72 (23%), Positives = 32/72 (44%)

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           QL +W  +    V+  +GH   +   A    G +VV+   DG  ++W+     C     +
Sbjct: 157 QLKIWSAEDASCVVTFKGHKGGILDTAIVDRGRNVVSASRDGTARLWDCGRSACLGVLAD 216

Query: 311 HKATVSGVTCSA 322
             ++++GV   A
Sbjct: 217 CGSSINGVAVGA 228


>AK074917-1|BAC11291.1|  421|Homo sapiens protein ( Homo sapiens
           cDNA FLJ90436 fis, clone NT2RP3000820, weakly similar to
           PUTATIVE SERINE/THREONINE-PROTEIN KINASE PKWA (EC
           2.7.1.-). ).
          Length = 421

 Score = 66.1 bits (154), Expect = 4e-10
 Identities = 47/180 (26%), Positives = 81/180 (45%), Gaps = 8/180 (4%)

Query: 253 LVWEWQSEQYVMKQQGHSLDMTC--LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           +VW       V ++Q   +++      +  D L + TG  +G++K+W+   G   +   +
Sbjct: 109 IVWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVD 168

Query: 311 HKATVSGVTCSAN-KKFFVSSSLDGTVRCYDLTRYRN-FRTLTSPSLVQFSCVALDSSGE 368
           H   V  +T + +     VS+S D T+R +DL    N  + L       +SC     S  
Sbjct: 169 HTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSM 228

Query: 369 FCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
            C+ G      +F+W++    ++  L GH   V +  FSP      LA+AS+D  V +WD
Sbjct: 229 LCSVGASKA--VFLWNMDKYTMIRKLEGHHHDVVACDFSP--DGALLATASYDTRVYIWD 284



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 56/238 (23%), Positives = 98/238 (41%), Gaps = 23/238 (9%)

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG-LHVVTGGFDGKVKVWNTTN-GFCF 305
           N G++ +W+  + + ++    H+  +  L ++PDG L +V+   D  ++VW+  + G   
Sbjct: 148 NNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMM 207

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
                H+  V     S +     S      V  +++ +Y   R L        +C     
Sbjct: 208 KVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGHHHDVVAC-DFSP 266

Query: 366 SGEFCAAGGQDVFEIFVWS-------IKFGKLLE------VLGGHEAPVSSLAFSPTLTS 412
            G   A    D   +++W        ++FG L          G ++  V S++FS     
Sbjct: 267 DGALLATASYDT-RVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHD--G 323

Query: 413 TRLASASWDGTVRLWDCI-DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
             +AS + D  VR W    D  VQ  P+   S+ L  AF  DG  +A  T DG++ F+
Sbjct: 324 LHVASLADDKMVRFWRIDEDYPVQVAPL---SNGLCCAFSTDGSVLAAGTHDGSVYFW 378



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 46/181 (25%), Positives = 74/181 (40%), Gaps = 16/181 (8%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVM--KQQGHSLDM 273
           D N++  L   ++ + S + SP    +   C       V+ W  ++Y M  K +GH  D+
Sbjct: 203 DGNMMKVLRGHQNWVYSCAFSPDSSML---CSVGASKAVFLWNMDKYTMIRKLEGHHHDV 259

Query: 274 TCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF-HEHKATVSGVTCSANKKFF--VSS 330
               +SPDG  + T  +D +V +W+  NG   + F H            AN ++   VS 
Sbjct: 260 VACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSF 319

Query: 331 SLDGT-VRCYDLTRYRNFRTLTSPSLVQFS------CVALDSSGEFCAAGGQDVFEIFVW 383
           S DG  V      +   F  +     VQ +      C A  + G   AAG  D   ++ W
Sbjct: 320 SHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHD-GSVYFW 378

Query: 384 S 384
           +
Sbjct: 379 A 379



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 5/92 (5%)

Query: 382 VWSIKF-GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
           VW +K  G +++VL GH+  V S AFSP   S+ L S      V LW+ +D+      + 
Sbjct: 197 VWDLKDDGNMMKVLRGHQNWVYSCAFSPD--SSMLCSVGASKAVFLWN-MDKYTMIRKLE 253

Query: 441 -LNSDALQVAFRPDGEEIAVSTLDGNITFFEP 471
             + D +   F PDG  +A ++ D  +  ++P
Sbjct: 254 GHHHDVVACDFSPDGALLATASYDTRVYIWDP 285



 Score = 41.1 bits (92), Expect = 0.014
 Identities = 32/150 (21%), Positives = 61/150 (40%), Gaps = 1/150 (0%)

Query: 192 QYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ 251
           ++ ++  LL TG ++G   + ++    L+  L      +  ++ +P G  I  +      
Sbjct: 135 RFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKT 194

Query: 252 LLVWEWQSEQYVMK-QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           L VW+ + +  +MK  +GH   +   A+SPD   + + G    V +WN            
Sbjct: 195 LRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEG 254

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
           H   V     S +     ++S D  V  +D
Sbjct: 255 HHHDVVACDFSPDGALLATASYDTRVYIWD 284


>L13387-1|AAA02882.1|  288|Homo sapiens Miller-Dieker lissencephaly
           protein protein.
          Length = 288

 Score = 65.7 bits (153), Expect = 6e-10
 Identities = 63/259 (24%), Positives = 107/259 (41%), Gaps = 25/259 (9%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIG 250
           + +    KLL +  +     L +      I T+   +H +SS+++ P GD I  A  +  
Sbjct: 34  ISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPNGDHIVSASRD-K 92

Query: 251 QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
            + +WE Q+   V    GH   +  +  + DG  + +   D  V+VW      C     E
Sbjct: 93  TIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVVATKECKAELRE 152

Query: 311 HK--------------ATVSGVTCSANKK------FFVSSSLDGTVRCYDLTRYRNFRTL 350
           H+              +++S  T S  KK      F +S S D T++ +D++      T 
Sbjct: 153 HEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDKTIKMWDVSTGMCLMTX 212

Query: 351 TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTL 410
                     V   S G+F  +   D   + VW  K  + ++ L  HE  V+SL F    
Sbjct: 213 VGHDN-WVRGVLFHSGGKFILSCADDK-TLRVWDYKNKRCMKTLNAHEHFVTSLDFHK-- 268

Query: 411 TSTRLASASWDGTVRLWDC 429
           T+  + + S D TV++W+C
Sbjct: 269 TAPYVVTGSVDQTVKVWEC 287



 Score = 59.7 bits (138), Expect = 4e-08
 Identities = 55/226 (24%), Positives = 93/226 (41%), Gaps = 23/226 (10%)

Query: 222 TLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPD 281
           TL      +  IS    G  +A +C     + +W++Q  + +    GH  +++ +A  P+
Sbjct: 23  TLKGHTDSVQDISFDHSGKLLA-SCSADMTIKLWDFQGFECIRTMHGHDHNVSSVAIMPN 81

Query: 282 GLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
           G H+V+   D  +K+W    G+C  TF  H+  V  V  + +     S S D TVR + +
Sbjct: 82  GDHIVSASRDKTIKMWEVQTGYCVKTFTGHREWVRMVRPNQDGTLIASCSNDQTVRVWVV 141

Query: 342 -TRYRNFRTLTSPSLVQFSCVALDSS------------------GEFCAAGGQDVFEIFV 382
            T+           +V+    A +SS                  G F  +G +D   I +
Sbjct: 142 ATKECKAELREHEHVVECISWAPESSYSSISEATGSETKKSGKPGPFLLSGSRDK-TIKM 200

Query: 383 WSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           W +  G  L    GH+  V  + F        + S + D T+R+WD
Sbjct: 201 WDVSTGMCLMTXVGHDNWVRGVLFHS--GGKFILSCADDKTLRVWD 244



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 36/170 (21%), Positives = 73/170 (42%), Gaps = 2/170 (1%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           VW++++  +    +GH+  +  +++   G  + +   D  +K+W+     C  T H H  
Sbjct: 12  VWDYETGDFERTLKGHTDSVQDISFDHSGKLLASCSADMTIKLWDFQGFECIRTMHGHDH 71

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            VS V    N    VS+S D T++ +++      +T T         V  +  G   A+ 
Sbjct: 72  NVSSVAIMPNGDHIVSASRDKTIKMWEVQTGYCVKTFTG-HREWVRMVRPNQDGTLIASC 130

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
             D   + VW +   +    L  HE  V  ++++P  + + ++ A+   T
Sbjct: 131 SNDQ-TVRVWVVATKECKAELREHEHVVECISWAPESSYSSISEATGSET 179



 Score = 39.9 bits (89), Expect = 0.032
 Identities = 28/94 (29%), Positives = 41/94 (43%), Gaps = 2/94 (2%)

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I VW  + G     L GH   V  ++F    +   LAS S D T++LWD    E      
Sbjct: 10  IKVWDYETGDFERTLKGHTDSVQDISFDH--SGKLLASCSADMTIKLWDFQGFECIRTMH 67

Query: 440 RLNSDALQVAFRPDGEEIAVSTLDGNITFFEPST 473
             + +   VA  P+G+ I  ++ D  I  +E  T
Sbjct: 68  GHDHNVSSVAIMPNGDHIVSASRDKTIKMWEVQT 101


>AK127882-1|BAC87175.1|  369|Homo sapiens protein ( Homo sapiens
           cDNA FLJ45988 fis, clone PUAEN2006639, weakly  similar
           to Vegetatible incompatibility protein HET-E-1. ).
          Length = 369

 Score = 65.7 bits (153), Expect = 6e-10
 Identities = 56/240 (23%), Positives = 97/240 (40%), Gaps = 6/240 (2%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPP-GDWIAFAC 246
           LT V  +K     +TG       L +      ++TL    + + +I+ + P GD IA   
Sbjct: 95  LTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGDKIATGS 154

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            +     +W  ++ +     +GH+ ++ CL+++P    V TG  D   K+W+  NG    
Sbjct: 155 FD-KTCKLWSVETGKCYHTFRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVY 213

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSS 366
           T   H A +  ++ + +    ++ S D TV  +D    R    L      + S  + +  
Sbjct: 214 TLRGHSAEIISLSFNTSGDRIITGSFDHTVVVWDADTGRKVNILIG-HCAEISSASFNWD 272

Query: 367 GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRL 426
                 G  D     +W    GK +  L GH+  +    F    T   +A+AS D  V L
Sbjct: 273 CSLILTGSMDK-TCKLWDATNGKCVATLTGHDDEILDSCFD--YTGKLIATASADDGVSL 329



 Score = 61.3 bits (142), Expect = 1e-08
 Identities = 39/163 (23%), Positives = 75/163 (46%), Gaps = 5/163 (3%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC-SANKK 325
           + H L +T +A +  G   +TG +D   K+W++ +G    T   H+  V  +   +    
Sbjct: 89  KAHILPLTNVALNKSGSCFITGSYDRTCKLWDSASGEELNTLEGHRNVVYAIAFNNPYGD 148

Query: 326 FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSI 385
              + S D T + + +   + + T    +  +  C++ +      A G  D     +W I
Sbjct: 149 KIATGSFDKTCKLWSVETGKCYHTFRGHT-AEIVCLSFNPQSTLVATGSMDT-TAKLWDI 206

Query: 386 KFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           + G+ +  L GH A + SL+F+   +  R+ + S+D TV +WD
Sbjct: 207 QNGEEVYTLRGHSAEIISLSFN--TSGDRIITGSFDHTVVVWD 247



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 43/192 (22%), Positives = 80/192 (41%), Gaps = 2/192 (1%)

Query: 187 KLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFAC 246
           ++  + ++ ++ L+ TG       L ++ +   ++TL      I S+S +  GD I    
Sbjct: 179 EIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEVYTLRGHSAEIISLSFNTSGDRIITGS 238

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            +   ++VW+  + + V    GH  +++  +++ D   ++TG  D   K+W+ TNG C  
Sbjct: 239 FD-HTVVVWDADTGRKVNILIGHCAEISSASFNWDCSLILTGSMDKTCKLWDATNGKCVA 297

Query: 307 TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT-LTSPSLVQFSCVALDS 365
           T   H   +         K   ++S D  V      R    R+ LT+    Q   + L  
Sbjct: 298 TLTGHDDEILDSCFDYTGKLIATASADDGVSLCRPGRSAVARSWLTATCASQVQAILLPQ 357

Query: 366 SGEFCAAGGQDV 377
             E C   G  V
Sbjct: 358 PPELCHVLGNHV 369



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 2/78 (2%)

Query: 20  FKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERK 79
           F+    E+ CL ++  S L+A GS DTT K+  ++  E +  Y+L GH+ +II + F   
Sbjct: 173 FRGHTAEIVCLSFNPQSTLVATGSMDTTAKLWDIQNGEEV--YTLRGHSAEIISLSFNTS 230

Query: 80  SLDLITVSRNGQLCLWEA 97
              +IT S +  + +W+A
Sbjct: 231 GDRIITGSFDHTVVVWDA 248


>U05340-1|AAA19017.1|  499|Homo sapiens p55CDC protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>DQ473545-1|ABE96834.1|  499|Homo sapiens CDC20 cell division cycle
           20 homolog protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BT007388-1|AAP36052.1|  499|Homo sapiens CDC20 cell division cycle
           20 homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC130473-1|AAI30474.1|  522|Homo sapiens transducin (beta)-like
           1Y-linked protein.
          Length = 522

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 56/222 (25%), Positives = 96/222 (43%), Gaps = 12/222 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G +V++ G D    +W+   G     F  H A    V    N   F 
Sbjct: 275 HKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNMTFA 333

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L      +T    +  + + +  D SG   A+   D+  + +WS+K  
Sbjct: 334 SCSTDMCIHVCRLGCDHPVKTFQGHTN-EVNAIKWDPSGMLLASCSDDM-TLKIWSMKQD 391

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT  +T        LASAS+D TVRLWD +++ V    +  
Sbjct: 392 ACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD-VEQGVCTHTLMK 450

Query: 442 NSDAL-QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
           + + +  VAF PDG+ +A  + D  +  +   +     S +G
Sbjct: 451 HQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 51/201 (25%), Positives = 80/201 (39%), Gaps = 15/201 (7%)

Query: 151 QNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLTAVQYHKENKLLVTGFSSGLFF 210
           QNN    S   D  +   +LG  +     +    +V   A+++     LL +        
Sbjct: 327 QNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLK 384

Query: 211 LHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLL--------VWEWQSEQY 262
           +  M     +H L      I +I  SP G   A + PN   +L        V  W  EQ 
Sbjct: 385 IWSMKQDACVHDLQAHSKEIYTIKWSPTGP--ATSNPNSSIMLASASFDSTVRLWDVEQG 442

Query: 263 VMKQ--QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           V       H   +  +A+SPDG ++ +G FD  V +WNT +G   V  ++    +  V  
Sbjct: 443 VCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSG-SLVHSYQGTGGIFEVCW 501

Query: 321 SANKKFFVSSSLDGTVRCYDL 341
           +A      +S+ DG+V   DL
Sbjct: 502 NARGDKVGASASDGSVCVLDL 522



 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 54/290 (18%), Positives = 118/290 (40%), Gaps = 29/290 (10%)

Query: 261 QYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
           ++ +++ GH +    D+T L ++ DG  +  G +DG  ++W T NG    T  +HK  + 
Sbjct: 222 RHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIF 280

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            +  +    + +S+ +D T   +D       + F   ++P+L       +D       A 
Sbjct: 281 ALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPAL------DVDWQNNMTFAS 334

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDRE 433
                 I V  +     ++   GH   V+++ + P  +   LAS S D T+++W  + ++
Sbjct: 335 CSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS-MKQD 391

Query: 434 VQCEPIRLNS-DALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSGRAE 492
                ++ +S +   + + P G   +            P++     S    S +     E
Sbjct: 392 ACVHDLQAHSKEIYTIKWSPTGPATS-----------NPNSSIMLASASFDSTVRLWDVE 440

Query: 493 TDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKF 542
             + T   +   +   ++ +S DG  +  G   K V +++ +   L+  +
Sbjct: 441 QGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490



 Score = 34.3 bits (75), Expect = 1.6
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 5/73 (6%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSG-HTDKIIGVFFERKSLDLI 84
           +VT LDW+S   LLA+GS D   +I T    EN  + S  G H   I  + + +K   ++
Sbjct: 237 DVTSLDWNSDGTLLAMGSYDGFARIWT----ENGNLASTLGQHKGPIFALKWNKKGNYVL 292

Query: 85  TVSRNGQLCLWEA 97
           +   +    +W+A
Sbjct: 293 SAGVDKTTIIWDA 305



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           VL GHE+ V   A++P   S  LAS S D T R+W+
Sbjct: 174 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWN 207


>BC130471-1|AAI30472.1|  522|Homo sapiens transducin (beta)-like
           1Y-linked protein.
          Length = 522

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 56/222 (25%), Positives = 96/222 (43%), Gaps = 12/222 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G +V++ G D    +W+   G     F  H A    V    N   F 
Sbjct: 275 HKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNMTFA 333

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L      +T    +  + + +  D SG   A+   D+  + +WS+K  
Sbjct: 334 SCSTDMCIHVCRLGCDHPVKTFQGHTN-EVNAIKWDPSGMLLASCSDDM-TLKIWSMKQD 391

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT  +T        LASAS+D TVRLWD +++ V    +  
Sbjct: 392 ACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD-VEQGVCTHTLMK 450

Query: 442 NSDAL-QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
           + + +  VAF PDG+ +A  + D  +  +   +     S +G
Sbjct: 451 HQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 51/201 (25%), Positives = 80/201 (39%), Gaps = 15/201 (7%)

Query: 151 QNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLTAVQYHKENKLLVTGFSSGLFF 210
           QNN    S   D  +   +LG  +     +    +V   A+++     LL +        
Sbjct: 327 QNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLK 384

Query: 211 LHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLL--------VWEWQSEQY 262
           +  M     +H L      I +I  SP G   A + PN   +L        V  W  EQ 
Sbjct: 385 IWSMKQDACVHDLQAHSKEIYTIKWSPTGP--ATSNPNSSIMLASASFDSTVRLWDVEQG 442

Query: 263 VMKQ--QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           V       H   +  +A+SPDG ++ +G FD  V +WNT +G   V  ++    +  V  
Sbjct: 443 VCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSG-SLVHSYQGTGGIFEVCW 501

Query: 321 SANKKFFVSSSLDGTVRCYDL 341
           +A      +S+ DG+V   DL
Sbjct: 502 NARGDKVGASASDGSVCVLDL 522



 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 54/290 (18%), Positives = 118/290 (40%), Gaps = 29/290 (10%)

Query: 261 QYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
           ++ +++ GH +    D+T L ++ DG  +  G +DG  ++W T NG    T  +HK  + 
Sbjct: 222 RHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIF 280

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            +  +    + +S+ +D T   +D       + F   ++P+L       +D       A 
Sbjct: 281 ALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPAL------DVDWQNNMTFAS 334

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDRE 433
                 I V  +     ++   GH   V+++ + P  +   LAS S D T+++W  + ++
Sbjct: 335 CSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS-MKQD 391

Query: 434 VQCEPIRLNS-DALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSGRAE 492
                ++ +S +   + + P G   +            P++     S    S +     E
Sbjct: 392 ACVHDLQAHSKEIYTIKWSPTGPATS-----------NPNSSIMLASASFDSTVRLWDVE 440

Query: 493 TDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKF 542
             + T   +   +   ++ +S DG  +  G   K V +++ +   L+  +
Sbjct: 441 QGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490



 Score = 34.3 bits (75), Expect = 1.6
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 5/73 (6%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSG-HTDKIIGVFFERKSLDLI 84
           +VT LDW+S   LLA+GS D   +I T    EN  + S  G H   I  + + +K   ++
Sbjct: 237 DVTSLDWNSDGTLLAMGSYDGFARIWT----ENGNLASTLGQHKGPIFALKWNKKGNYVL 292

Query: 85  TVSRNGQLCLWEA 97
           +   +    +W+A
Sbjct: 293 SAGVDKTTIIWDA 305



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           VL GHE+ V   A++P   S  LAS S D T R+W+
Sbjct: 174 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWN 207


>BC110321-1|AAI10322.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC106004-1|AAI06005.1|  514|Homo sapiens pleiotropic regulator 1
           (PRL1 homolog, Arabidopsis) protein.
          Length = 514

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 55/232 (23%), Positives = 96/232 (41%), Gaps = 7/232 (3%)

Query: 197 NKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWE 256
           N+  VTG +     + ++    L  +L+     +  + VS    ++ F+C    Q+  W+
Sbjct: 216 NQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL-FSCGEDKQVKCWD 274

Query: 257 WQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
            +  + +    GH   +  L   P    +VT   D   ++W+        T   H   V+
Sbjct: 275 LEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVA 334

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQD 376
            V C A +   ++ S D T+R +DL   +   TLT+        V L       A+G  D
Sbjct: 335 TVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHK-KSVRAVVLHPRHYTFASGSPD 393

Query: 377 VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
              I  W    G  ++ L GH A +++L  +   +   L S + +GT+ LWD
Sbjct: 394 --NIKQWKFPDGSFIQNLSGHNAIINTLTVN---SDGVLVSGADNGTMHLWD 440



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 39/163 (23%), Positives = 69/163 (42%), Gaps = 4/163 (2%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+A  P     VTG  D  +K+W+  +G   ++   H +TV GV  S    + 
Sbjct: 202 GHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 261

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
            S   D  V+C+DL   +  R         +  + L  + +      +D     +W ++ 
Sbjct: 262 FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYG-LDLHPTIDVLVTCSRD-STARIWDVRT 319

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
              +  L GH   V+++         ++ + S D T+RLWD +
Sbjct: 320 KASVHTLSGHTNAVATVRCQ--AAEPQIITGSHDTTIRLWDLV 360



 Score = 34.3 bits (75), Expect = 1.6
 Identities = 18/87 (20%), Positives = 41/87 (47%), Gaps = 1/87 (1%)

Query: 223 LSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG 282
           ++++ H+ S  +V        FA  +   +  W++    ++    GH+  +  L  + DG
Sbjct: 366 VTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG 425

Query: 283 LHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           + +V+G  +G + +W+   G+ F   H
Sbjct: 426 V-LVSGADNGTMHLWDWRTGYNFQRVH 451



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 8/109 (7%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           EY   I  R +   L  V  LD      +L   S+D+T +I  V      ++++LSGHT+
Sbjct: 276 EYNKVI--RHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR--TKASVHTLSGHTN 331

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVR 118
            +  V  +     +IT S +  + LW+       + +    T+ KK VR
Sbjct: 332 AVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL----TNHKKSVR 376


>BC031294-1|AAH31294.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC024257-1|AAH24257.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC020786-1|AAH20786.1|  505|Homo sapiens PLRG1 protein protein.
          Length = 505

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 55/232 (23%), Positives = 96/232 (41%), Gaps = 7/232 (3%)

Query: 197 NKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWE 256
           N+  VTG +     + ++    L  +L+     +  + VS    ++ F+C    Q+  W+
Sbjct: 207 NQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL-FSCGEDKQVKCWD 265

Query: 257 WQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
            +  + +    GH   +  L   P    +VT   D   ++W+        T   H   V+
Sbjct: 266 LEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVA 325

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQD 376
            V C A +   ++ S D T+R +DL   +   TLT+        V L       A+G  D
Sbjct: 326 TVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHK-KSVRAVVLHPRHYTFASGSPD 384

Query: 377 VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
              I  W    G  ++ L GH A +++L  +   +   L S + +GT+ LWD
Sbjct: 385 --NIKQWKFPDGSFIQNLSGHNAIINTLTVN---SDGVLVSGADNGTMHLWD 431



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 39/163 (23%), Positives = 69/163 (42%), Gaps = 4/163 (2%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+A  P     VTG  D  +K+W+  +G   ++   H +TV GV  S    + 
Sbjct: 193 GHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 252

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
            S   D  V+C+DL   +  R         +  + L  + +      +D     +W ++ 
Sbjct: 253 FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYG-LDLHPTIDVLVTCSRD-STARIWDVRT 310

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
              +  L GH   V+++         ++ + S D T+RLWD +
Sbjct: 311 KASVHTLSGHTNAVATVRCQ--AAEPQIITGSHDTTIRLWDLV 351



 Score = 34.3 bits (75), Expect = 1.6
 Identities = 18/87 (20%), Positives = 41/87 (47%), Gaps = 1/87 (1%)

Query: 223 LSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG 282
           ++++ H+ S  +V        FA  +   +  W++    ++    GH+  +  L  + DG
Sbjct: 357 VTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG 416

Query: 283 LHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           + +V+G  +G + +W+   G+ F   H
Sbjct: 417 V-LVSGADNGTMHLWDWRTGYNFQRVH 442



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 8/109 (7%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           EY   I  R +   L  V  LD      +L   S+D+T +I  V      ++++LSGHT+
Sbjct: 267 EYNKVI--RHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR--TKASVHTLSGHTN 322

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVR 118
            +  V  +     +IT S +  + LW+       + +    T+ KK VR
Sbjct: 323 AVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL----TNHKKSVR 367


>BC015998-1|AAH15998.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC013303-1|AAH13303.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC012827-1|AAH12827.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC012803-1|AAH12803.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC012075-1|AAH12075.1|  485|Homo sapiens notchless homolog 1
           (Drosophila) protein.
          Length = 485

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 60/247 (24%), Positives = 109/247 (44%), Gaps = 15/247 (6%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLI-HTLSISEHRISSISVSP----PGDWIAF 244
           ++ +  + K L +G  +G   L +      +  TL+     I+ +S  P    P      
Sbjct: 161 SISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVA 220

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +    G + +W+  + +      GH+  +TCL +  DGL + +   D  +KVW   +G  
Sbjct: 221 SSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVL 279

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSS--SLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVA 362
             T   H   V+ +  S +      +    + +V   DL    + + L   +L +++ V 
Sbjct: 280 CRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQG--SLQELKERALSRYNLVR 337

Query: 363 LDSSGEFCAAGGQDVFEIFVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               G      G D F +F+WS  +  K L  + GH+A ++ + FSP   S  +ASAS+D
Sbjct: 338 --GQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD--SRIVASASFD 393

Query: 422 GTVRLWD 428
            +++LWD
Sbjct: 394 KSIKLWD 400



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 56/194 (28%), Positives = 92/194 (47%), Gaps = 12/194 (6%)

Query: 222 TLSISEHRISSISV--SPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYS 279
           T S+  H  + ISV  SP G ++A    +   +  W+  +E      +GH   +  +++S
Sbjct: 107 TSSLEGHSEAVISVAFSPTGKYLASGSGDT-TVRFWDLSTETPHFTCKGHRHWVLSISWS 165

Query: 280 PDGLHVVTGGFDGKVKVWNTTNG-FCFVTFHEHKATVSGVT---CSANK--KFFVSSSLD 333
           PDG  + +G  +G++ +W+ + G     T   H   ++G++     AN   ++  SSS D
Sbjct: 166 PDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKD 225

Query: 334 GTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEV 393
           G+VR +D T  R  R LT  +    +C+     G   +A  QD   I VW    G L   
Sbjct: 226 GSVRIWDTTAGRCERILTGHT-QSVTCLRWGGDGLLYSA-SQD-RTIKVWRAHDGVLCRT 282

Query: 394 LGGHEAPVSSLAFS 407
           L GH   V+++A S
Sbjct: 283 LQGHGHWVNTMALS 296



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 394 LGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPD 453
           L GH   V S+AFSPT     LAS S D TVR WD                 L +++ PD
Sbjct: 110 LEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 167

Query: 454 GEEIAVSTLDGNITFFEPSTCEQTG 478
           G+++A    +G I  ++PST +Q G
Sbjct: 168 GKKLASGCKNGQILLWDPSTGKQVG 192



 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 43/170 (25%), Positives = 77/170 (45%), Gaps = 9/170 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  +  +A+SP G ++ +G  D  V+ W+ +      T   H+  V  ++ S + K 
Sbjct: 111 EGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKK 170

Query: 327 FVSSSLDGTVRCYDLTRYRNF-RTLTSPS--LVQFSCVALDSSGE--FCAAGGQDVFEIF 381
             S   +G +  +D +  +   RTL   S  +   S   L ++ E  + A+  +D   + 
Sbjct: 171 LASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKD-GSVR 229

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCID 431
           +W    G+   +L GH   V+ L +        L SAS D T+++W   D
Sbjct: 230 IWDTTAGRCERILTGHTQSVTCLRWG---GDGLLYSASQDRTIKVWRAHD 276



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 2/126 (1%)

Query: 252 LLVWE-WQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           L +W   + ++ + +  GH   +  + +SPD   V +  FD  +K+W+   G    +   
Sbjct: 353 LFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRG 412

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H A V  +  SA+ +  VS S D T++ +D+   +    L   +  +   V     G+  
Sbjct: 413 HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHA-DEVYAVDWSPDGQRV 471

Query: 371 AAGGQD 376
           A+GG+D
Sbjct: 472 ASGGKD 477



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 6/129 (4%)

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           C  +   H   V  V  S   K+  S S D TVR +DL+      T         S ++ 
Sbjct: 106 CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLS-ISW 164

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLL-EVLGGHEAPVSSLAFSPTLTSTR---LASAS 419
              G+  A+G ++  +I +W    GK +   L GH   ++ L++ P   +     +AS+S
Sbjct: 165 SPDGKKLASGCKN-GQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSS 223

Query: 420 WDGTVRLWD 428
            DG+VR+WD
Sbjct: 224 KDGSVRIWD 232



 Score = 40.7 bits (91), Expect = 0.018
 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I +W  + GK L  L GH A V  +A+S    S  L S S D T+++WD   +++  +  
Sbjct: 396 IKLWDGRTGKYLASLRGHVAAVYQIAWS--ADSRLLVSGSSDSTLKVWDVKAQKLAMDLP 453

Query: 440 RLNSDALQVAFRPDGEEIA 458
               +   V + PDG+ +A
Sbjct: 454 GHADEVYAVDWSPDGQRVA 472



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 15/46 (32%), Positives = 29/46 (63%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
           L VW+ ++++  M   GH+ ++  + +SPDG  V +GG D  +++W
Sbjct: 438 LKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483



 Score = 35.5 bits (78), Expect = 0.69
 Identities = 25/110 (22%), Positives = 49/110 (44%), Gaps = 1/110 (0%)

Query: 230 ISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           I+ +  SP    +A A  +   + +W+ ++ +Y+   +GH   +  +A+S D   +V+G 
Sbjct: 375 INQVLFSPDSRIVASASFD-KSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGS 433

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCY 339
            D  +KVW+       +    H   V  V  S + +   S   D  +R +
Sbjct: 434 SDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483



 Score = 34.7 bits (76), Expect = 1.2
 Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 2/64 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           WS+ SRLL  GS D+T K+  V+  + + M  L GH D++  V +      + +  ++  
Sbjct: 422 WSADSRLLVSGSSDSTLKVWDVK-AQKLAM-DLPGHADEVYAVDWSPDGQRVASGGKDKC 479

Query: 92  LCLW 95
           L +W
Sbjct: 480 LRIW 483



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 2/74 (2%)

Query: 25  DEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLI 84
           + V  + +S   + LA GS DTT +   +        ++  GH   ++ + +      L 
Sbjct: 115 EAVISVAFSPTGKYLASGSGDTTVRFWDLS--TETPHFTCKGHRHWVLSISWSPDGKKLA 172

Query: 85  TVSRNGQLCLWEAS 98
           +  +NGQ+ LW+ S
Sbjct: 173 SGCKNGQILLWDPS 186


>BC010044-1|AAH10044.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC009426-1|AAH09426.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC009425-1|AAH09425.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC006272-1|AAH06272.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC002884-1|AAH02884.2|  484|Homo sapiens NLE1 protein protein.
          Length = 484

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 60/247 (24%), Positives = 109/247 (44%), Gaps = 15/247 (6%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLI-HTLSISEHRISSISVSP----PGDWIAF 244
           ++ +  + K L +G  +G   L +      +  TL+     I+ +S  P    P      
Sbjct: 160 SISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVA 219

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +    G + +W+  + +      GH+  +TCL +  DGL + +   D  +KVW   +G  
Sbjct: 220 SSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVL 278

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSS--SLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVA 362
             T   H   V+ +  S +      +    + +V   DL    + + L   +L +++ V 
Sbjct: 279 CRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQG--SLQELKERALSRYNLVR 336

Query: 363 LDSSGEFCAAGGQDVFEIFVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               G      G D F +F+WS  +  K L  + GH+A ++ + FSP   S  +ASAS+D
Sbjct: 337 --GQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD--SRIVASASFD 392

Query: 422 GTVRLWD 428
            +++LWD
Sbjct: 393 KSIKLWD 399



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 56/194 (28%), Positives = 92/194 (47%), Gaps = 12/194 (6%)

Query: 222 TLSISEHRISSISV--SPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYS 279
           T S+  H  + ISV  SP G ++A    +   +  W+  +E      +GH   +  +++S
Sbjct: 106 TSSLEGHSEAVISVAFSPTGKYLASGSGDT-TVRFWDLSTETPHFTCKGHRHWVLSISWS 164

Query: 280 PDGLHVVTGGFDGKVKVWNTTNG-FCFVTFHEHKATVSGVT---CSANK--KFFVSSSLD 333
           PDG  + +G  +G++ +W+ + G     T   H   ++G++     AN   ++  SSS D
Sbjct: 165 PDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKD 224

Query: 334 GTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEV 393
           G+VR +D T  R  R LT  +    +C+     G   +A  QD   I VW    G L   
Sbjct: 225 GSVRIWDTTAGRCERILTGHT-QSVTCLRWGGDGLLYSA-SQD-RTIKVWRAHDGVLCRT 281

Query: 394 LGGHEAPVSSLAFS 407
           L GH   V+++A S
Sbjct: 282 LQGHGHWVNTMALS 295



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 394 LGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPD 453
           L GH   V S+AFSPT     LAS S D TVR WD                 L +++ PD
Sbjct: 109 LEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 166

Query: 454 GEEIAVSTLDGNITFFEPSTCEQTG 478
           G+++A    +G I  ++PST +Q G
Sbjct: 167 GKKLASGCKNGQILLWDPSTGKQVG 191



 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 43/170 (25%), Positives = 77/170 (45%), Gaps = 9/170 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  +  +A+SP G ++ +G  D  V+ W+ +      T   H+  V  ++ S + K 
Sbjct: 110 EGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKK 169

Query: 327 FVSSSLDGTVRCYDLTRYRNF-RTLTSPS--LVQFSCVALDSSGE--FCAAGGQDVFEIF 381
             S   +G +  +D +  +   RTL   S  +   S   L ++ E  + A+  +D   + 
Sbjct: 170 LASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKD-GSVR 228

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCID 431
           +W    G+   +L GH   V+ L +        L SAS D T+++W   D
Sbjct: 229 IWDTTAGRCERILTGHTQSVTCLRWG---GDGLLYSASQDRTIKVWRAHD 275



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 2/126 (1%)

Query: 252 LLVWE-WQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           L +W   + ++ + +  GH   +  + +SPD   V +  FD  +K+W+   G    +   
Sbjct: 352 LFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRG 411

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H A V  +  SA+ +  VS S D T++ +D+   +    L   +  +   V     G+  
Sbjct: 412 HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHA-DEVYAVDWSPDGQRV 470

Query: 371 AAGGQD 376
           A+GG+D
Sbjct: 471 ASGGKD 476



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 6/129 (4%)

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           C  +   H   V  V  S   K+  S S D TVR +DL+      T         S ++ 
Sbjct: 105 CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLS-ISW 163

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLL-EVLGGHEAPVSSLAFSPTLTSTR---LASAS 419
              G+  A+G ++  +I +W    GK +   L GH   ++ L++ P   +     +AS+S
Sbjct: 164 SPDGKKLASGCKN-GQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSS 222

Query: 420 WDGTVRLWD 428
            DG+VR+WD
Sbjct: 223 KDGSVRIWD 231



 Score = 40.7 bits (91), Expect = 0.018
 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I +W  + GK L  L GH A V  +A+S    S  L S S D T+++WD   +++  +  
Sbjct: 395 IKLWDGRTGKYLASLRGHVAAVYQIAWS--ADSRLLVSGSSDSTLKVWDVKAQKLAMDLP 452

Query: 440 RLNSDALQVAFRPDGEEIA 458
               +   V + PDG+ +A
Sbjct: 453 GHADEVYAVDWSPDGQRVA 471



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 15/46 (32%), Positives = 29/46 (63%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
           L VW+ ++++  M   GH+ ++  + +SPDG  V +GG D  +++W
Sbjct: 437 LKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482



 Score = 35.5 bits (78), Expect = 0.69
 Identities = 25/110 (22%), Positives = 49/110 (44%), Gaps = 1/110 (0%)

Query: 230 ISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           I+ +  SP    +A A  +   + +W+ ++ +Y+   +GH   +  +A+S D   +V+G 
Sbjct: 374 INQVLFSPDSRIVASASFD-KSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGS 432

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCY 339
            D  +KVW+       +    H   V  V  S + +   S   D  +R +
Sbjct: 433 SDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 482



 Score = 34.7 bits (76), Expect = 1.2
 Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 2/64 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           WS+ SRLL  GS D+T K+  V+  + + M  L GH D++  V +      + +  ++  
Sbjct: 421 WSADSRLLVSGSSDSTLKVWDVK-AQKLAM-DLPGHADEVYAVDWSPDGQRVASGGKDKC 478

Query: 92  LCLW 95
           L +W
Sbjct: 479 LRIW 482



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 2/74 (2%)

Query: 25  DEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLI 84
           + V  + +S   + LA GS DTT +   +        ++  GH   ++ + +      L 
Sbjct: 114 EAVISVAFSPTGKYLASGSGDTTVRFWDLS--TETPHFTCKGHRHWVLSISWSPDGKKLA 171

Query: 85  TVSRNGQLCLWEAS 98
           +  +NGQ+ LW+ S
Sbjct: 172 SGCKNGQILLWDPS 185


>BC001088-1|AAH01088.1|  499|Homo sapiens cell division cycle 20
           homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>BC000624-1|AAH00624.1|  499|Homo sapiens CDC20 protein protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>AL139289-3|CAB92757.1|  499|Homo sapiens CDC20 cell division cycle
           20 homolog (S. cerevisiae) protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>AK001320-1|BAA91621.1|  485|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10458 fis, clone NT2RP1001457, highly similar to
           Homo sapiens partial mRNA for beta-transducin family
           protein. ).
          Length = 485

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 60/247 (24%), Positives = 109/247 (44%), Gaps = 15/247 (6%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLI-HTLSISEHRISSISVSP----PGDWIAF 244
           ++ +  + K L +G  +G   L +      +  TL+     I+ +S  P    P      
Sbjct: 161 SISWSPDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVA 220

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +    G + +W+  + +      GH+  +TCL +  DGL + +   D  +KVW   +G  
Sbjct: 221 SSSKDGSVRIWDTTAGRCERILTGHTQSVTCLRWGGDGL-LYSASQDRTIKVWRAHDGVL 279

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSS--SLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVA 362
             T   H   V+ +  S +      +    + +V   DL    + + L   +L +++ V 
Sbjct: 280 CRTLQGHGHWVNTMALSTDYALRTGAFEPAEASVNPQDLQG--SLQELKERALSRYNLVR 337

Query: 363 LDSSGEFCAAGGQDVFEIFVWS-IKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
               G      G D F +F+WS  +  K L  + GH+A ++ + FSP   S  +ASAS+D
Sbjct: 338 --GQGPERLVSGSDDFTLFLWSPAEDKKPLTRMTGHQALINQVLFSPD--SRIVASASFD 393

Query: 422 GTVRLWD 428
            +++LWD
Sbjct: 394 KSIKLWD 400



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 56/194 (28%), Positives = 92/194 (47%), Gaps = 12/194 (6%)

Query: 222 TLSISEHRISSISV--SPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYS 279
           T S+  H  + ISV  SP G ++A    +   +  W+  +E      +GH   +  +++S
Sbjct: 107 TSSLEGHSEAVISVAFSPTGKYLASGSGDT-TVRFWDLSTETPHFTCKGHRHWVLSISWS 165

Query: 280 PDGLHVVTGGFDGKVKVWNTTNG-FCFVTFHEHKATVSGVT---CSANK--KFFVSSSLD 333
           PDG  + +G  +G++ +W+ + G     T   H   ++G++     AN   ++  SSS D
Sbjct: 166 PDGKKLASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKD 225

Query: 334 GTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEV 393
           G+VR +D T  R  R LT  +    +C+     G   +A  QD   I VW    G L   
Sbjct: 226 GSVRIWDTTAGRCERILTGHT-QSVTCLRWGGDGLLYSA-SQD-RTIKVWRAHDGVLCRT 282

Query: 394 LGGHEAPVSSLAFS 407
           L GH   V+++A S
Sbjct: 283 LQGHGHWVNTMALS 296



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 32/85 (37%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 394 LGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPD 453
           L GH   V S+AFSPT     LAS S D TVR WD                 L +++ PD
Sbjct: 110 LEGHSEAVISVAFSPT--GKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPD 167

Query: 454 GEEIAVSTLDGNITFFEPSTCEQTG 478
           G+++A    +G I  ++PST +Q G
Sbjct: 168 GKKLASGCKNGQILLWDPSTGKQVG 192



 Score = 52.4 bits (120), Expect = 6e-06
 Identities = 43/170 (25%), Positives = 77/170 (45%), Gaps = 9/170 (5%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           +GHS  +  +A+SP G ++ +G  D  V+ W+ +      T   H+  V  ++ S + K 
Sbjct: 111 EGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLSISWSPDGKK 170

Query: 327 FVSSSLDGTVRCYDLTRYRNF-RTLTSPS--LVQFSCVALDSSGE--FCAAGGQDVFEIF 381
             S   +G +  +D +  +   RTL   S  +   S   L ++ E  + A+  +D   + 
Sbjct: 171 LASGCKNGQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSSKD-GSVR 229

Query: 382 VWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCID 431
           +W    G+   +L GH   V+ L +        L SAS D T+++W   D
Sbjct: 230 IWDTTAGRCERILTGHTQSVTCLRWG---GDGLLYSASQDRTIKVWRAHD 276



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 31/126 (24%), Positives = 58/126 (46%), Gaps = 2/126 (1%)

Query: 252 LLVWE-WQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHE 310
           L +W   + ++ + +  GH   +  + +SPD   V +  FD  +K+W+   G    +   
Sbjct: 353 LFLWSPAEDKKPLTRMTGHQALINQVLFSPDSRIVASASFDKSIKLWDGRTGKYLASLRG 412

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H A V  +  SA+ +  VS S D T++ +D+   +    L   +  +   V     G+  
Sbjct: 413 HVAAVYQIAWSADSRLLVSGSSDSTLKVWDVKAQKLAMDLPGHA-DEVYAVDWSPDGQRV 471

Query: 371 AAGGQD 376
           A+GG+D
Sbjct: 472 ASGGKD 477



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 37/129 (28%), Positives = 59/129 (45%), Gaps = 6/129 (4%)

Query: 304 CFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL 363
           C  +   H   V  V  S   K+  S S D TVR +DL+      T         S ++ 
Sbjct: 106 CTSSLEGHSEAVISVAFSPTGKYLASGSGDTTVRFWDLSTETPHFTCKGHRHWVLS-ISW 164

Query: 364 DSSGEFCAAGGQDVFEIFVWSIKFGKLL-EVLGGHEAPVSSLAFSPTLTSTR---LASAS 419
              G+  A+G ++  +I +W    GK +   L GH   ++ L++ P   +     +AS+S
Sbjct: 165 SPDGKKLASGCKN-GQILLWDPSTGKQVGRTLAGHSKWITGLSWEPLHANPECRYVASSS 223

Query: 420 WDGTVRLWD 428
            DG+VR+WD
Sbjct: 224 KDGSVRIWD 232



 Score = 40.7 bits (91), Expect = 0.018
 Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 2/79 (2%)

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPI 439
           I +W  + GK L  L GH A V  +A+S    S  L S S D T+++WD   +++  +  
Sbjct: 396 IKLWDGRTGKYLASLRGHVAAVYQIAWS--ADSRLLVSGSSDSTLKVWDVKAQKLAMDLP 453

Query: 440 RLNSDALQVAFRPDGEEIA 458
               +   V + PDG+ +A
Sbjct: 454 GHADEVYAVDWSPDGQRVA 472



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 15/46 (32%), Positives = 29/46 (63%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
           L VW+ ++++  M   GH+ ++  + +SPDG  V +GG D  +++W
Sbjct: 438 LKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483



 Score = 35.5 bits (78), Expect = 0.69
 Identities = 25/110 (22%), Positives = 49/110 (44%), Gaps = 1/110 (0%)

Query: 230 ISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGG 289
           I+ +  SP    +A A  +   + +W+ ++ +Y+   +GH   +  +A+S D   +V+G 
Sbjct: 375 INQVLFSPDSRIVASASFD-KSIKLWDGRTGKYLASLRGHVAAVYQIAWSADSRLLVSGS 433

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCY 339
            D  +KVW+       +    H   V  V  S + +   S   D  +R +
Sbjct: 434 SDSTLKVWDVKAQKLAMDLPGHADEVYAVDWSPDGQRVASGGKDKCLRIW 483



 Score = 34.7 bits (76), Expect = 1.2
 Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 2/64 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           WS+ SRLL  GS D+T K+  V+  + + M  L GH D++  V +      + +  ++  
Sbjct: 422 WSADSRLLVSGSSDSTLKVWDVK-AQKLAM-DLPGHADEVYAVDWSPDGQRVASGGKDKC 479

Query: 92  LCLW 95
           L +W
Sbjct: 480 LRIW 483



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 18/74 (24%), Positives = 34/74 (45%), Gaps = 2/74 (2%)

Query: 25  DEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLI 84
           + V  + +S   + LA GS DTT +   +        ++  GH   ++ + +      L 
Sbjct: 115 EAVISVAFSPTGKYLASGSGDTTVRFWDLS--TETPHFTCKGHRHWVLSISWSPDGKKLA 172

Query: 85  TVSRNGQLCLWEAS 98
           +  +NGQ+ LW+ S
Sbjct: 173 SGCKNGQILLWDPS 186


>AF332222-1|AAK13474.1|  522|Homo sapiens transducin beta-like 1
           protein.
          Length = 522

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 56/222 (25%), Positives = 96/222 (43%), Gaps = 12/222 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G +V++ G D    +W+   G     F  H A    V    N   F 
Sbjct: 275 HKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNMTFA 333

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L      +T    +  + + +  D SG   A+   D+  + +WS+K  
Sbjct: 334 SCSTDMCIHVCRLGCDHPVKTFQGHTN-EVNAIKWDPSGMLLASCSDDM-TLKIWSMKQD 391

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT  +T        LASAS+D TVRLWD +++ V    +  
Sbjct: 392 ACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD-VEQGVCTHTLMK 450

Query: 442 NSDAL-QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
           + + +  VAF PDG+ +A  + D  +  +   +     S +G
Sbjct: 451 HQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 51/201 (25%), Positives = 80/201 (39%), Gaps = 15/201 (7%)

Query: 151 QNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLTAVQYHKENKLLVTGFSSGLFF 210
           QNN    S   D  +   +LG  +     +    +V   A+++     LL +        
Sbjct: 327 QNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLK 384

Query: 211 LHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLL--------VWEWQSEQY 262
           +  M     +H L      I +I  SP G   A + PN   +L        V  W  EQ 
Sbjct: 385 IWSMKQDACVHDLQAHSKEIYTIKWSPTGP--ATSNPNSSIMLASASFDSTVRLWDVEQG 442

Query: 263 VMKQ--QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           V       H   +  +A+SPDG ++ +G FD  V +WNT +G   V  ++    +  V  
Sbjct: 443 VCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSG-SLVHSYQGTGGIFEVCW 501

Query: 321 SANKKFFVSSSLDGTVRCYDL 341
           +A      +S+ DG+V   DL
Sbjct: 502 NARGDKVGASASDGSVCVLDL 522



 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 54/290 (18%), Positives = 118/290 (40%), Gaps = 29/290 (10%)

Query: 261 QYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
           ++ +++ GH +    D+T L ++ DG  +  G +DG  ++W T NG    T  +HK  + 
Sbjct: 222 RHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIF 280

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            +  +    + +S+ +D T   +D       + F   ++P+L       +D       A 
Sbjct: 281 ALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPAL------DVDWQNNMTFAS 334

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDRE 433
                 I V  +     ++   GH   V+++ + P  +   LAS S D T+++W  + ++
Sbjct: 335 CSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS-MKQD 391

Query: 434 VQCEPIRLNS-DALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSGRAE 492
                ++ +S +   + + P G   +            P++     S    S +     E
Sbjct: 392 ACVHDLQAHSKEIYTIKWSPTGPATS-----------NPNSSIMLASASFDSTVRLWDVE 440

Query: 493 TDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKF 542
             + T   +   +   ++ +S DG  +  G   K V +++ +   L+  +
Sbjct: 441 QGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490



 Score = 34.3 bits (75), Expect = 1.6
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 5/73 (6%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSG-HTDKIIGVFFERKSLDLI 84
           +VT LDW+S   LLA+GS D   +I T    EN  + S  G H   I  + + +K   ++
Sbjct: 237 DVTSLDWNSDGTLLAMGSYDGFARIWT----ENGNLASTLGQHKGPIFALKWNKKGNYVL 292

Query: 85  TVSRNGQLCLWEA 97
           +   +    +W+A
Sbjct: 293 SAGVDKTTIIWDA 305



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           VL GHE+ V   A++P   S  LAS S D T R+W+
Sbjct: 174 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWN 207


>AF332221-1|AAK13473.1|  522|Homo sapiens transducin beta-like 1
           protein.
          Length = 522

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 56/222 (25%), Positives = 96/222 (43%), Gaps = 12/222 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G +V++ G D    +W+   G     F  H A    V    N   F 
Sbjct: 275 HKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNMTFA 333

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L      +T    +  + + +  D SG   A+   D+  + +WS+K  
Sbjct: 334 SCSTDMCIHVCRLGCDHPVKTFQGHTN-EVNAIKWDPSGMLLASCSDDM-TLKIWSMKQD 391

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT  +T        LASAS+D TVRLWD +++ V    +  
Sbjct: 392 ACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD-VEQGVCTHTLMK 450

Query: 442 NSDAL-QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
           + + +  VAF PDG+ +A  + D  +  +   +     S +G
Sbjct: 451 HQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 51/201 (25%), Positives = 80/201 (39%), Gaps = 15/201 (7%)

Query: 151 QNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLTAVQYHKENKLLVTGFSSGLFF 210
           QNN    S   D  +   +LG  +     +    +V   A+++     LL +        
Sbjct: 327 QNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLK 384

Query: 211 LHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLL--------VWEWQSEQY 262
           +  M     +H L      I +I  SP G   A + PN   +L        V  W  EQ 
Sbjct: 385 IWSMKQDACVHDLQAHSKEIYTIKWSPTGP--ATSNPNSSIMLASASFDSTVRLWDVEQG 442

Query: 263 VMKQ--QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           V       H   +  +A+SPDG ++ +G FD  V +WNT +G   V  ++    +  V  
Sbjct: 443 VCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSG-SLVHSYQGTGGIFEVCW 501

Query: 321 SANKKFFVSSSLDGTVRCYDL 341
           +A      +S+ DG+V   DL
Sbjct: 502 NARGDKVGASASDGSVCVLDL 522



 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 54/290 (18%), Positives = 118/290 (40%), Gaps = 29/290 (10%)

Query: 261 QYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
           ++ +++ GH +    D+T L ++ DG  +  G +DG  ++W T NG    T  +HK  + 
Sbjct: 222 RHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIF 280

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            +  +    + +S+ +D T   +D       + F   ++P+L       +D       A 
Sbjct: 281 ALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPAL------DVDWQNNMTFAS 334

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDRE 433
                 I V  +     ++   GH   V+++ + P  +   LAS S D T+++W  + ++
Sbjct: 335 CSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS-MKQD 391

Query: 434 VQCEPIRLNS-DALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSGRAE 492
                ++ +S +   + + P G   +            P++     S    S +     E
Sbjct: 392 ACVHDLQAHSKEIYTIKWSPTGPATS-----------NPNSSIMLASASFDSTVRLWDVE 440

Query: 493 TDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKF 542
             + T   +   +   ++ +S DG  +  G   K V +++ +   L+  +
Sbjct: 441 QGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490



 Score = 34.3 bits (75), Expect = 1.6
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 5/73 (6%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSG-HTDKIIGVFFERKSLDLI 84
           +VT LDW+S   LLA+GS D   +I T    EN  + S  G H   I  + + +K   ++
Sbjct: 237 DVTSLDWNSDGTLLAMGSYDGFARIWT----ENGNLASTLGQHKGPIFALKWNKKGNYVL 292

Query: 85  TVSRNGQLCLWEA 97
           +   +    +W+A
Sbjct: 293 SAGVDKTTIIWDA 305



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           VL GHE+ V   A++P   S  LAS S D T R+W+
Sbjct: 174 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWN 207


>AF332220-1|AAK13472.1|  522|Homo sapiens transducin beta-like 1
           protein.
          Length = 522

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 56/222 (25%), Positives = 96/222 (43%), Gaps = 12/222 (5%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L ++  G +V++ G D    +W+   G     F  H A    V    N   F 
Sbjct: 275 HKGPIFALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ-NNMTFA 333

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S S D  +    L      +T    +  + + +  D SG   A+   D+  + +WS+K  
Sbjct: 334 SCSTDMCIHVCRLGCDHPVKTFQGHTN-EVNAIKWDPSGMLLASCSDDM-TLKIWSMKQD 391

Query: 389 KLLEVLGGHEAPVSSLAFSPTLTSTR-------LASASWDGTVRLWDCIDREVQCEPIRL 441
             +  L  H   + ++ +SPT  +T        LASAS+D TVRLWD +++ V    +  
Sbjct: 392 ACVHDLQAHSKEIYTIKWSPTGPATSNPNSSIMLASASFDSTVRLWD-VEQGVCTHTLMK 450

Query: 442 NSDAL-QVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
           + + +  VAF PDG+ +A  + D  +  +   +     S +G
Sbjct: 451 HQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSYQG 492



 Score = 45.6 bits (103), Expect = 6e-04
 Identities = 51/201 (25%), Positives = 80/201 (39%), Gaps = 15/201 (7%)

Query: 151 QNNSKVNSEENDKRLMYKKLGRHYIGDAIRNADRKVKLTAVQYHKENKLLVTGFSSGLFF 210
           QNN    S   D  +   +LG  +     +    +V   A+++     LL +        
Sbjct: 327 QNNMTFASCSTDMCIHVCRLGCDHPVKTFQGHTNEVN--AIKWDPSGMLLASCSDDMTLK 384

Query: 211 LHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLL--------VWEWQSEQY 262
           +  M     +H L      I +I  SP G   A + PN   +L        V  W  EQ 
Sbjct: 385 IWSMKQDACVHDLQAHSKEIYTIKWSPTGP--ATSNPNSSIMLASASFDSTVRLWDVEQG 442

Query: 263 VMKQ--QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           V       H   +  +A+SPDG ++ +G FD  V +WNT +G   V  ++    +  V  
Sbjct: 443 VCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSG-SLVHSYQGTGGIFEVCW 501

Query: 321 SANKKFFVSSSLDGTVRCYDL 341
           +A      +S+ DG+V   DL
Sbjct: 502 NARGDKVGASASDGSVCVLDL 522



 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 54/290 (18%), Positives = 118/290 (40%), Gaps = 29/290 (10%)

Query: 261 QYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
           ++ +++ GH +    D+T L ++ DG  +  G +DG  ++W T NG    T  +HK  + 
Sbjct: 222 RHCIREGGHDVPSNKDVTSLDWNSDGTLLAMGSYDGFARIW-TENGNLASTLGQHKGPIF 280

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDL---TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            +  +    + +S+ +D T   +D       + F   ++P+L       +D       A 
Sbjct: 281 ALKWNKKGNYVLSAGVDKTTIIWDAHTGEAKQQFPFHSAPAL------DVDWQNNMTFAS 334

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDRE 433
                 I V  +     ++   GH   V+++ + P  +   LAS S D T+++W  + ++
Sbjct: 335 CSTDMCIHVCRLGCDHPVKTFQGHTNEVNAIKWDP--SGMLLASCSDDMTLKIWS-MKQD 391

Query: 434 VQCEPIRLNS-DALQVAFRPDGEEIAVSTLDGNITFFEPSTCEQTGSVEGRSDLGSGRAE 492
                ++ +S +   + + P G   +            P++     S    S +     E
Sbjct: 392 ACVHDLQAHSKEIYTIKWSPTGPATS-----------NPNSSIMLASASFDSTVRLWDVE 440

Query: 493 TDLVTPQTLLKTKAFTTICYSADGTCILGGGNSKNVCLYSVKDSVLIKKF 542
             + T   +   +   ++ +S DG  +  G   K V +++ +   L+  +
Sbjct: 441 QGVCTHTLMKHQEPVYSVAFSPDGKYLASGSFDKYVHIWNTQSGSLVHSY 490



 Score = 34.3 bits (75), Expect = 1.6
 Identities = 23/73 (31%), Positives = 37/73 (50%), Gaps = 5/73 (6%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSG-HTDKIIGVFFERKSLDLI 84
           +VT LDW+S   LLA+GS D   +I T    EN  + S  G H   I  + + +K   ++
Sbjct: 237 DVTSLDWNSDGTLLAMGSYDGFARIWT----ENGNLASTLGQHKGPIFALKWNKKGNYVL 292

Query: 85  TVSRNGQLCLWEA 97
           +   +    +W+A
Sbjct: 293 SAGVDKTTIIWDA 305



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 2/36 (5%)

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           VL GHE+ V   A++P   S  LAS S D T R+W+
Sbjct: 174 VLRGHESEVFICAWNPV--SDLLASGSGDSTARIWN 207


>AF099644-1|AAD16405.1|  499|Homo sapiens cell cycle protein CDC20
           protein.
          Length = 499

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 62/252 (24%), Positives = 109/252 (43%), Gaps = 14/252 (5%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           +++V + KE   L  G SS    L ++     +  ++    R+ S+S +    +I  +  
Sbjct: 229 ISSVAWIKEGNYLAVGTSSAEVQLWDVQQQKRLRNMTSHSARVGSLSWN---SYILSSGS 285

Query: 248 NIGQLLVWEWQ-SEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG---- 302
             G +   + + +E +V    GHS ++  L ++PDG H+ +GG D  V VW +  G    
Sbjct: 286 RSGHIHHHDVRVAEHHVATLSGHSQEVCGLRWAPDGRHLASGGNDNLVNVWPSAPGEGGW 345

Query: 303 FCFVTFHEHKATVSGVT-C--SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFS 359
               TF +H+  V  V  C   +N       + D  +R +++        + + S V  S
Sbjct: 346 VPLQTFTQHQGAVKAVAWCPWQSNVLATGGGTSDRHIRIWNVCSGACLSAVDAHSQV-CS 404

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +      E  +  G    ++ +W       +  L GH + V SL  SP      +ASA+
Sbjct: 405 ILWSPHYKELISGHGFAQNQLVIWKYPTMAKVAELKGHTSRVLSLTMSP--DGATVASAA 462

Query: 420 WDGTVRLWDCID 431
            D T+RLW C +
Sbjct: 463 ADETLRLWRCFE 474


>AF044333-1|AAD09407.1|  514|Homo sapiens pleiotropic regulator 1
           protein.
          Length = 514

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 55/232 (23%), Positives = 96/232 (41%), Gaps = 7/232 (3%)

Query: 197 NKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWE 256
           N+  VTG +     + ++    L  +L+     +  + VS    ++ F+C    Q+  W+
Sbjct: 216 NQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL-FSCGEDKQVKCWD 274

Query: 257 WQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVS 316
            +  + +    GH   +  L   P    +VT   D   ++W+        T   H   V+
Sbjct: 275 LEYNKVIRHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVRTKASVHTLSGHTNAVA 334

Query: 317 GVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQD 376
            V C A +   ++ S D T+R +DL   +   TLT+        V L       A+G  D
Sbjct: 335 TVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTLTNHK-KSVRAVVLHPRHYTFASGSPD 393

Query: 377 VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
              I  W    G  ++ L GH A +++L  +   +   L S + +GT+ LWD
Sbjct: 394 --NIKQWKFPDGSFIQNLSGHNAIINTLTVN---SDGVLVSGADNGTMHLWD 440



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 39/163 (23%), Positives = 69/163 (42%), Gaps = 4/163 (2%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+A  P     VTG  D  +K+W+  +G   ++   H +TV GV  S    + 
Sbjct: 202 GHLGWVRCIAVEPGNQWFVTGSADRTIKIWDLASGKLKLSLTGHISTVRGVIVSTRSPYL 261

Query: 328 VSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
            S   D  V+C+DL   +  R         +  + L  + +      +D     +W ++ 
Sbjct: 262 FSCGEDKQVKCWDLEYNKVIRHYHGHLSAVYG-LDLHPTIDVLVTCSRD-STARIWDVRT 319

Query: 388 GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
              +  L GH   V+++         ++ + S D T+RLWD +
Sbjct: 320 KASVHTLSGHTNAVATVRCQ--AAEPQIITGSHDTTIRLWDLV 360



 Score = 34.3 bits (75), Expect = 1.6
 Identities = 18/87 (20%), Positives = 41/87 (47%), Gaps = 1/87 (1%)

Query: 223 LSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG 282
           ++++ H+ S  +V        FA  +   +  W++    ++    GH+  +  L  + DG
Sbjct: 366 VTLTNHKKSVRAVVLHPRHYTFASGSPDNIKQWKFPDGSFIQNLSGHNAIINTLTVNSDG 425

Query: 283 LHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           + +V+G  +G + +W+   G+ F   H
Sbjct: 426 V-LVSGADNGTMHLWDWRTGYNFQRVH 451



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 30/109 (27%), Positives = 49/109 (44%), Gaps = 8/109 (7%)

Query: 10  EYRPFIMKRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTD 69
           EY   I  R +   L  V  LD      +L   S+D+T +I  V      ++++LSGHT+
Sbjct: 276 EYNKVI--RHYHGHLSAVYGLDLHPTIDVLVTCSRDSTARIWDVR--TKASVHTLSGHTN 331

Query: 70  KIIGVFFERKSLDLITVSRNGQLCLWEASIDADELAVKQDDTSRKKRVR 118
            +  V  +     +IT S +  + LW+       + +    T+ KK VR
Sbjct: 332 AVATVRCQAAEPQIITGSHDTTIRLWDLVAGKTRVTL----TNHKKSVR 376


>AC006011-2|AAX82033.1| 1336|Homo sapiens unknown protein.
          Length = 1336

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 57/218 (26%), Positives = 93/218 (42%), Gaps = 12/218 (5%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTC 275
           ++N +      +  I   S SP  +  A  C + G + +W++         +GH  D+ C
Sbjct: 191 NMNNVKMFQAHKEAIREASFSPTDNKFA-TCSDDGTVRIWDFLRCHEERILRGHGADVKC 249

Query: 276 LAYSPDGLHVVTGGFDGK--VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLD 333
           + + P    VV+G  D +  +K W+   G    T H HK TV  V  + N  + +++S D
Sbjct: 250 VDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRD 309

Query: 334 GTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGE-FCAAGGQDVFEIFVWSIKFGKLLE 392
              + +D+   +    +      + + VA     E   A+GG D   +F W +   K  E
Sbjct: 310 HLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLF-WHVGVEK--E 366

Query: 393 VLG---GHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           V G    HE  + SLA+ P      L S S D T + W
Sbjct: 367 VGGMEMAHEGMIWSLAWHP--LGHILCSGSNDHTSKFW 402



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 57/235 (24%), Positives = 97/235 (41%), Gaps = 7/235 (2%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           G+  +W   +  +    Q H   +  + +S + + ++T    G VK W  +N      F 
Sbjct: 141 GEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQ-SNMNNVKMFQ 199

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEF 369
            HK  +   + S     F + S DGTVR +D  R    R L         CV    +   
Sbjct: 200 AHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHG-ADVKCVDWHPTKGL 258

Query: 370 CAAGGQDVFE-IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             +G +D  + I  W  K G+ L  L  H+  V  +  +  L    L +AS D   +L+D
Sbjct: 259 VVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN--LNGNWLLTASRDHLCKLFD 316

Query: 429 CIDREVQCEPIR-LNSDALQVAFRPDGEEI-AVSTLDGNITFFEPSTCEQTGSVE 481
             + + + +  R    +A  VA+ P  E + A    DG++ F+     ++ G +E
Sbjct: 317 IRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGME 371



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 70/299 (23%), Positives = 127/299 (42%), Gaps = 15/299 (5%)

Query: 179 IRNADRKVK--LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVS 236
           +R +  KVK  +  V++  E + LVTG SSG F L      N    L   +  + +++ S
Sbjct: 111 VRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWS 170

Query: 237 PPGDWIAFACPNIGQLLVWEWQSEQYVMKQ-QGHSLDMTCLAYSPDGLHVVTGGFDGKVK 295
               W+  A  + G  + + WQS    +K  Q H   +   ++SP      T   DG V+
Sbjct: 171 HNDMWMLTA--DHGGYVKY-WQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVR 227

Query: 296 VWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDG--TVRCYDLTRYRNFRTLTSP 353
           +W+            H A V  V     K   VS S D    ++ +D    ++  TL + 
Sbjct: 228 IWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAH 287

Query: 354 SLVQFSCVALDSSGEFCAAGGQD-VFEIF-VWSIKFGKLLEVLGGHEAPVSSLAFSPTLT 411
                  V L+ +G +     +D + ++F + ++K  + L+V  GH+   +++A+ P + 
Sbjct: 288 KNTVME-VKLNLNGNWLLTASRDHLCKLFDIRNLK--EELQVFRGHKKEATAVAWHP-VH 343

Query: 412 STRLASASWDGTVRLWDC-IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
               AS   DG++  W   +++EV    +        +A+ P G  +   + D    F+
Sbjct: 344 EGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFW 402



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 12/101 (11%)

Query: 391 LEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL----NSDAL 446
           +++   H+  +   +FSPT    + A+ S DGTVR+WD +    +C   R+     +D  
Sbjct: 195 VKMFQAHKEAIREASFSPT--DNKFATCSDDGTVRIWDFL----RCHEERILRGHGADVK 248

Query: 447 QVAFRPDGEEIAVSTLDGN--ITFFEPSTCEQTGSVEGRSD 485
            V + P    +   + D    I F++P T +   ++    +
Sbjct: 249 CVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKN 289



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 22/90 (24%), Positives = 41/90 (45%)

Query: 17  KRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF 76
           +R+ +    +V C+DW     L+  GSKD+   I   +     ++ +L  H + ++ V  
Sbjct: 237 ERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKL 296

Query: 77  ERKSLDLITVSRNGQLCLWEASIDADELAV 106
                 L+T SR+    L++     +EL V
Sbjct: 297 NLNGNWLLTASRDHLCKLFDIRNLKEELQV 326


>AB044749-1|BAB32435.1| 1336|Homo sapiens WDC146 protein.
          Length = 1336

 Score = 64.5 bits (150), Expect = 1e-09
 Identities = 57/218 (26%), Positives = 93/218 (42%), Gaps = 12/218 (5%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTC 275
           ++N +      +  I   S SP  +  A  C + G + +W++         +GH  D+ C
Sbjct: 191 NMNNVKMFQAHKEAIREASFSPTDNKFA-TCSDDGTVRIWDFLRCHEERILRGHGADVKC 249

Query: 276 LAYSPDGLHVVTGGFDGK--VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLD 333
           + + P    VV+G  D +  +K W+   G    T H HK TV  V  + N  + +++S D
Sbjct: 250 VDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLNLNGNWLLTASRD 309

Query: 334 GTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGE-FCAAGGQDVFEIFVWSIKFGKLLE 392
              + +D+   +    +      + + VA     E   A+GG D   +F W +   K  E
Sbjct: 310 HLCKLFDIRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLF-WHVGVEK--E 366

Query: 393 VLG---GHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           V G    HE  + SLA+ P      L S S D T + W
Sbjct: 367 VGGMEMAHEGMIWSLAWHP--LGHILCSGSNDHTSKFW 402



 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 57/235 (24%), Positives = 97/235 (41%), Gaps = 7/235 (2%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           G+  +W   +  +    Q H   +  + +S + + ++T    G VK W  +N      F 
Sbjct: 141 GEFTLWNGLTFNFETILQAHDSPVRAMTWSHNDMWMLTADHGGYVKYWQ-SNMNNVKMFQ 199

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEF 369
            HK  +   + S     F + S DGTVR +D  R    R L         CV    +   
Sbjct: 200 AHKEAIREASFSPTDNKFATCSDDGTVRIWDFLRCHEERILRGHG-ADVKCVDWHPTKGL 258

Query: 370 CAAGGQDVFE-IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             +G +D  + I  W  K G+ L  L  H+  V  +  +  L    L +AS D   +L+D
Sbjct: 259 VVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKLN--LNGNWLLTASRDHLCKLFD 316

Query: 429 CIDREVQCEPIR-LNSDALQVAFRPDGEEI-AVSTLDGNITFFEPSTCEQTGSVE 481
             + + + +  R    +A  VA+ P  E + A    DG++ F+     ++ G +E
Sbjct: 317 IRNLKEELQVFRGHKKEATAVAWHPVHEGLFASGGSDGSLLFWHVGVEKEVGGME 371



 Score = 52.8 bits (121), Expect = 4e-06
 Identities = 70/299 (23%), Positives = 127/299 (42%), Gaps = 15/299 (5%)

Query: 179 IRNADRKVK--LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVS 236
           +R +  KVK  +  V++  E + LVTG SSG F L      N    L   +  + +++ S
Sbjct: 111 VRTSTNKVKCPVFVVRWTPEGRRLVTGASSGEFTLWNGLTFNFETILQAHDSPVRAMTWS 170

Query: 237 PPGDWIAFACPNIGQLLVWEWQSEQYVMKQ-QGHSLDMTCLAYSPDGLHVVTGGFDGKVK 295
               W+  A  + G  + + WQS    +K  Q H   +   ++SP      T   DG V+
Sbjct: 171 HNDMWMLTA--DHGGYVKY-WQSNMNNVKMFQAHKEAIREASFSPTDNKFATCSDDGTVR 227

Query: 296 VWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDG--TVRCYDLTRYRNFRTLTSP 353
           +W+            H A V  V     K   VS S D    ++ +D    ++  TL + 
Sbjct: 228 IWDFLRCHEERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAH 287

Query: 354 SLVQFSCVALDSSGEFCAAGGQD-VFEIF-VWSIKFGKLLEVLGGHEAPVSSLAFSPTLT 411
                  V L+ +G +     +D + ++F + ++K  + L+V  GH+   +++A+ P + 
Sbjct: 288 KNTVME-VKLNLNGNWLLTASRDHLCKLFDIRNLK--EELQVFRGHKKEATAVAWHP-VH 343

Query: 412 STRLASASWDGTVRLWDC-IDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
               AS   DG++  W   +++EV    +        +A+ P G  +   + D    F+
Sbjct: 344 EGLFASGGSDGSLLFWHVGVEKEVGGMEMAHEGMIWSLAWHPLGHILCSGSNDHTSKFW 402



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 12/101 (11%)

Query: 391 LEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRL----NSDAL 446
           +++   H+  +   +FSPT    + A+ S DGTVR+WD +    +C   R+     +D  
Sbjct: 195 VKMFQAHKEAIREASFSPT--DNKFATCSDDGTVRIWDFL----RCHEERILRGHGADVK 248

Query: 447 QVAFRPDGEEIAVSTLDGN--ITFFEPSTCEQTGSVEGRSD 485
            V + P    +   + D    I F++P T +   ++    +
Sbjct: 249 CVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKN 289



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 22/90 (24%), Positives = 41/90 (45%)

Query: 17  KRVFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF 76
           +R+ +    +V C+DW     L+  GSKD+   I   +     ++ +L  H + ++ V  
Sbjct: 237 ERILRGHGADVKCVDWHPTKGLVVSGSKDSQQPIKFWDPKTGQSLATLHAHKNTVMEVKL 296

Query: 77  ERKSLDLITVSRNGQLCLWEASIDADELAV 106
                 L+T SR+    L++     +EL V
Sbjct: 297 NLNGNWLLTASRDHLCKLFDIRNLKEELQV 326


>BC021905-1|AAH21905.1|  896|Homo sapiens Unknown (protein for
           IMAGE:4341693) protein.
          Length = 896

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 54/218 (24%), Positives = 91/218 (41%), Gaps = 25/218 (11%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GH+ +++ +A + +   +  G  D  ++VW             H A
Sbjct: 209 IWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSA 268

Query: 314 TVSGV----TCSANKKFFVSSSLDGTVRCYDL---------TRYRNFRTLTSPSLVQFSC 360
           +++ +     CS +K++  S+  DGT+ C+ L          R   F     P  VQ  C
Sbjct: 269 SITSLQFSPLCSGSKRYLSSTGADGTI-CFWLWDAGTLKINPRPAKFTERPRPG-VQMIC 326

Query: 361 VALDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +  + G F A G  D +  ++ +     + +  L  H   V S+ FS   TS R  S S
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSN--TSNRFVSGS 384

Query: 420 WDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEI 457
            DGT R+W    RE         S  L +A RP G+ +
Sbjct: 385 RDGTARIWQFKRRE-------WKSILLDMATRPAGQNL 415



 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 4/119 (3%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H ++V  VT     +   + S D  V+ +     R   TL   +  + S +A++      
Sbjct: 182 HLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHA-AEISDMAVNYENTMI 240

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR--LASASWDGTVRLW 427
           AAG  D   I VW ++    L VL GH A ++SL FSP  + ++  L+S   DGT+  W
Sbjct: 241 AAGSCDKM-IRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFW 298



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 4/120 (3%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+ +   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMI 240

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVW 383
            + S D  +R + L        L     S + +QFS +   S     + G       ++W
Sbjct: 241 AAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLW 300



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 49/179 (27%), Positives = 76/179 (42%), Gaps = 26/179 (14%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG----FCFVTFHEHKATVSGVTCSANKKF 326
           + M C ++S  G+ + TG  D  ++V+   +G       + FH  K  V  +  S     
Sbjct: 322 VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDK--VDSIQFSNTSNR 379

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTL-----TSPS------------LVQFSCVALDSSGEF 369
           FVS S DGT R +   R R ++++     T P+             ++ + VA D     
Sbjct: 380 FVSGSRDGTARIWQFKR-REWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNT 438

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
                 ++  + VW+   G+L+ VL GHE  V  L   P      L SA  DG V +WD
Sbjct: 439 VITAVNNM-TLKVWNSYTGQLIHVLMGHEDEVFVLEPHP-FDPRVLFSAGHDGNVIVWD 495



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 18/71 (25%), Positives = 34/71 (47%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           ++ C  +S+    LA GS D   +++     +   +  L  HTDK+  + F   S   ++
Sbjct: 323 QMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVS 382

Query: 86  VSRNGQLCLWE 96
            SR+G   +W+
Sbjct: 383 GSRDGTARIWQ 393



 Score = 34.7 bits (76), Expect = 1.2
 Identities = 25/106 (23%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++    +       LIH L   E  +  +   P    + F
Sbjct: 424 KMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLF 483

Query: 245 ACPNIGQLLVWEW------QSEQYVMKQQGHSLDMTCLAYSPDGLH 284
           +  + G ++VW+       +S   +++ QGH     C   SPDG H
Sbjct: 484 SAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKC-SPDGQH 528


>AL450327-2|CAH70884.1| 1821|Homo sapiens protein ( Human DNA
           sequence from clone RP11-173D14 on chromosome 6. ).
          Length = 1821

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 54/218 (24%), Positives = 91/218 (41%), Gaps = 25/218 (11%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GH+ +++ +A + +   +  G  D  ++VW             H A
Sbjct: 209 IWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSA 268

Query: 314 TVSGV----TCSANKKFFVSSSLDGTVRCYDL---------TRYRNFRTLTSPSLVQFSC 360
           +++ +     CS +K++  S+  DGT+ C+ L          R   F     P  VQ  C
Sbjct: 269 SITSLQFSPLCSGSKRYLSSTGADGTI-CFWLWDAGTLKINPRPAKFTERPRPG-VQMIC 326

Query: 361 VALDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +  + G F A G  D +  ++ +     + +  L  H   V S+ FS   TS R  S S
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSN--TSNRFVSGS 384

Query: 420 WDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEI 457
            DGT R+W    RE         S  L +A RP G+ +
Sbjct: 385 RDGTARIWQFKRRE-------WKSILLDMATRPAGQNL 415



 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 4/119 (3%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H ++V  VT     +   + S D  V+ +     R   TL   +  + S +A++      
Sbjct: 182 HLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHA-AEISDMAVNYENTMI 240

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR--LASASWDGTVRLW 427
           AAG  D   I VW ++    L VL GH A ++SL FSP  + ++  L+S   DGT+  W
Sbjct: 241 AAGSCDKM-IRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFW 298



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 4/120 (3%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+ +   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMI 240

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVW 383
            + S D  +R + L        L     S + +QFS +   S     + G       ++W
Sbjct: 241 AAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLW 300



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 49/179 (27%), Positives = 76/179 (42%), Gaps = 26/179 (14%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG----FCFVTFHEHKATVSGVTCSANKKF 326
           + M C ++S  G+ + TG  D  ++V+   +G       + FH  K  V  +  S     
Sbjct: 322 VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDK--VDSIQFSNTSNR 379

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTL-----TSPS------------LVQFSCVALDSSGEF 369
           FVS S DGT R +   R R ++++     T P+             ++ + VA D     
Sbjct: 380 FVSGSRDGTARIWQFKR-REWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNT 438

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
                 ++  + VW+   G+L+ VL GHE  V  L   P      L SA  DG V +WD
Sbjct: 439 VITAVNNM-TLKVWNSYTGQLIHVLMGHEDEVFVLEPHP-FDPRVLFSAGHDGNVIVWD 495



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 18/71 (25%), Positives = 34/71 (47%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           ++ C  +S+    LA GS D   +++     +   +  L  HTDK+  + F   S   ++
Sbjct: 323 QMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVS 382

Query: 86  VSRNGQLCLWE 96
            SR+G   +W+
Sbjct: 383 GSRDGTARIWQ 393



 Score = 34.7 bits (76), Expect = 1.2
 Identities = 25/106 (23%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++    +       LIH L   E  +  +   P    + F
Sbjct: 424 KMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLF 483

Query: 245 ACPNIGQLLVWEW------QSEQYVMKQQGHSLDMTCLAYSPDGLH 284
           +  + G ++VW+       +S   +++ QGH     C   SPDG H
Sbjct: 484 SAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKC-SPDGQH 528


>AL356776-2|CAI14406.1| 1821|Homo sapiens protein ( Human DNA
           sequence from clone RP11-477E3 on chromosome 6. ).
          Length = 1821

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 54/218 (24%), Positives = 91/218 (41%), Gaps = 25/218 (11%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GH+ +++ +A + +   +  G  D  ++VW             H A
Sbjct: 209 IWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSA 268

Query: 314 TVSGV----TCSANKKFFVSSSLDGTVRCYDL---------TRYRNFRTLTSPSLVQFSC 360
           +++ +     CS +K++  S+  DGT+ C+ L          R   F     P  VQ  C
Sbjct: 269 SITSLQFSPLCSGSKRYLSSTGADGTI-CFWLWDAGTLKINPRPAKFTERPRPG-VQMIC 326

Query: 361 VALDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +  + G F A G  D +  ++ +     + +  L  H   V S+ FS   TS R  S S
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSN--TSNRFVSGS 384

Query: 420 WDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEI 457
            DGT R+W    RE         S  L +A RP G+ +
Sbjct: 385 RDGTARIWQFKRRE-------WKSILLDMATRPAGQNL 415



 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 4/119 (3%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H ++V  VT     +   + S D  V+ +     R   TL   +  + S +A++      
Sbjct: 182 HLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHA-AEISDMAVNYENTMI 240

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR--LASASWDGTVRLW 427
           AAG  D   I VW ++    L VL GH A ++SL FSP  + ++  L+S   DGT+  W
Sbjct: 241 AAGSCDKM-IRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFW 298



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 4/120 (3%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+ +   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMI 240

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVW 383
            + S D  +R + L        L     S + +QFS +   S     + G       ++W
Sbjct: 241 AAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLW 300



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 49/179 (27%), Positives = 76/179 (42%), Gaps = 26/179 (14%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG----FCFVTFHEHKATVSGVTCSANKKF 326
           + M C ++S  G+ + TG  D  ++V+   +G       + FH  K  V  +  S     
Sbjct: 322 VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDK--VDSIQFSNTSNR 379

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTL-----TSPS------------LVQFSCVALDSSGEF 369
           FVS S DGT R +   R R ++++     T P+             ++ + VA D     
Sbjct: 380 FVSGSRDGTARIWQFKR-REWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNT 438

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
                 ++  + VW+   G+L+ VL GHE  V  L   P      L SA  DG V +WD
Sbjct: 439 VITAVNNM-TLKVWNSYTGQLIHVLMGHEDEVFVLEPHP-FDPRVLFSAGHDGNVIVWD 495



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 18/71 (25%), Positives = 34/71 (47%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           ++ C  +S+    LA GS D   +++     +   +  L  HTDK+  + F   S   ++
Sbjct: 323 QMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVS 382

Query: 86  VSRNGQLCLWE 96
            SR+G   +W+
Sbjct: 383 GSRDGTARIWQ 393



 Score = 34.7 bits (76), Expect = 1.2
 Identities = 25/106 (23%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++    +       LIH L   E  +  +   P    + F
Sbjct: 424 KMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLF 483

Query: 245 ACPNIGQLLVWEW------QSEQYVMKQQGHSLDMTCLAYSPDGLH 284
           +  + G ++VW+       +S   +++ QGH     C   SPDG H
Sbjct: 484 SAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKC-SPDGQH 528


>AL121993-4|CAI22739.1|  943|Homo sapiens WD repeat domain 3
           protein.
          Length = 943

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 43/184 (23%), Positives = 76/184 (41%), Gaps = 4/184 (2%)

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           A P    + +W+ +  + ++  QG   ++TCL  SPDGLH+  G  DG +++++  +G  
Sbjct: 40  AVPACEHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEG 99

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            VTF+ HKA ++ +          S S D  +  +D+        L          + L 
Sbjct: 100 NVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLR 159

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
                    G+D   +  W +      + + GH   V  L         RL + + D  +
Sbjct: 160 EK-NLLVTSGKDTM-VKWWDLDTQHCFKTMVGHRTEVWGLVL--LSEEKRLITGASDSEL 215

Query: 425 RLWD 428
           R+WD
Sbjct: 216 RVWD 219



 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 35/160 (21%), Positives = 70/160 (43%), Gaps = 3/160 (1%)

Query: 217 VNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCL 276
           V    TL + E  +  +S SP    +A +  +   + ++   + ++ +   GH L + C+
Sbjct: 540 VKQTRTLQLDED-VLCVSYSPNQKLLAVSLLDC-TVKIFYVDTLKFFLSLYGHKLPVICM 597

Query: 277 AYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTV 336
             S DG  + TG  D  VK+W    G C  +   H  +V  +        F ++  D  +
Sbjct: 598 DISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKI 657

Query: 337 RCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQD 376
           + +D  ++ + +TL      +  C+A+  SG++  +   D
Sbjct: 658 KQWDADKFEHIQTLEGHH-QEIWCLAVSPSGDYVVSSSHD 696



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 53/244 (21%), Positives = 107/244 (43%), Gaps = 18/244 (7%)

Query: 197 NKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ-LLVW 255
           ++ +V G  +G   L+++   NL+ T+   +  + S+S+SP  D   F      + +  W
Sbjct: 466 DRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSP--DQRGFVTGGADKSVKFW 523

Query: 256 EWQ-------SEQYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +++       +++ +  +Q  +L    D+ C++YSP+   +     D  VK++       
Sbjct: 524 DFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKF 583

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
           F++ + HK  V  +  S +     + S D  V+ + L      ++L +          + 
Sbjct: 584 FLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVP 643

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            S  F  AG     +I  W     + ++ L GH   +  LA SP  +   + S+S D ++
Sbjct: 644 KSHLFFTAGKD--HKIKQWDADKFEHIQTLEGHHQEIWCLAVSP--SGDYVVSSSHDKSL 699

Query: 425 RLWD 428
           RLW+
Sbjct: 700 RLWE 703



 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 23/90 (25%), Positives = 45/90 (50%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           ++VW+  +E  + + +GH   +T   +  +   +VT G D  VK W+     CF T   H
Sbjct: 131 IIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGH 190

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
           +  V G+   + +K  ++ + D  +R +D+
Sbjct: 191 RTEVWGLVLLSEEKRLITGASDSELRVWDI 220



 Score = 39.5 bits (88), Expect = 0.043
 Identities = 16/63 (25%), Positives = 31/63 (49%)

Query: 238 PGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
           P   + F      ++  W+    +++   +GH  ++ CLA SP G +VV+   D  +++W
Sbjct: 643 PKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702

Query: 298 NTT 300
             T
Sbjct: 703 ERT 705



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 52/270 (19%), Positives = 101/270 (37%), Gaps = 15/270 (5%)

Query: 223 LSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG 282
           ++I  HR    ++S   D IA        + +W   + Q +           C  + P  
Sbjct: 409 ITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMTCEYA--LCSFFVPGD 466

Query: 283 LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD-- 340
             VV G   GK+++++  +G    T   H   +  ++ S +++ FV+   D +V+ +D  
Sbjct: 467 RQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFE 526

Query: 341 LTRYRNF--------RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLE 392
           L +  N         +T T        CV+   + +  A    D   + ++ +   K   
Sbjct: 527 LVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDC-TVKIFYVDTLKFFL 585

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP 452
            L GH+ PV  +  S       +A+ S D  V++W     +        +   + + F P
Sbjct: 586 SLYGHKLPVICMDISH--DGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVP 643

Query: 453 DGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                  +  D  I  ++    E   ++EG
Sbjct: 644 KSHLFFTAGKDHKIKQWDADKFEHIQTLEG 673



 Score = 34.7 bits (76), Expect = 1.2
 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 2/70 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           +T L +      LA GSKDT   +  V  +    +Y L GH D I    F R+   L+T 
Sbjct: 110 ITTLKYDQLGGRLASGSKDTDIIVWDV--INESGLYRLKGHKDAITQALFLREKNLLVTS 167

Query: 87  SRNGQLCLWE 96
            ++  +  W+
Sbjct: 168 GKDTMVKWWD 177



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 39/170 (22%), Positives = 70/170 (41%), Gaps = 6/170 (3%)

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
           F      K  +  VT    K  +V+      V  +DL +      L      + +C+   
Sbjct: 16  FGVIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKQ-EVTCLCPS 74

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
             G   A G +D   I ++S+  G+      GH+A +++L +       RLAS S D  +
Sbjct: 75  PDGLHLAVGYEDG-SIRIFSLLSGEGNVTFNGHKAAITTLKYDQL--GGRLASGSKDTDI 131

Query: 425 RLWDCIDREVQCEPIRLNSDAL-QVAFRPDGEEIAVSTLDGNITFFEPST 473
            +WD I+ E     ++ + DA+ Q  F  +   +  S  D  + +++  T
Sbjct: 132 IVWDVIN-ESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDT 180



 Score = 32.3 bits (70), Expect = 6.5
 Identities = 20/75 (26%), Positives = 32/75 (42%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L + P      T G D K+K W+        T   H   +  +  S +  + V
Sbjct: 632 HDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVV 691

Query: 329 SSSLDGTVRCYDLTR 343
           SSS D ++R ++ TR
Sbjct: 692 SSSHDKSLRLWERTR 706



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 25  DEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLI 84
           ++V C+ +S   +LLAV   D T KI  V+ L+     SL GH   +I +        + 
Sbjct: 550 EDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLK--FFLSLYGHKLPVICMDISHDGALIA 607

Query: 85  TVSRNGQLCLWEASI-DADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEKEYDS 143
           T S +  + +W     D  +     DD+     + LQ        F A  D  K K++D+
Sbjct: 608 TGSADRNVKIWGLDFGDCHKSLFAHDDSV----MYLQFVPKSHLFFTAGKD-HKIKQWDA 662

Query: 144 DR 145
           D+
Sbjct: 663 DK 664


>AK057039-1|BAB71353.1|  912|Homo sapiens protein ( Homo sapiens
           cDNA FLJ32477 fis, clone SKNMC2000698, highly similar to
           Mus musculus ndrp mRNA for neuronal differentiaion
           related ).
          Length = 912

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 54/218 (24%), Positives = 91/218 (41%), Gaps = 25/218 (11%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GH+ +++ +A + +   +  G  D  ++VW             H A
Sbjct: 209 IWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSA 268

Query: 314 TVSGV----TCSANKKFFVSSSLDGTVRCYDL---------TRYRNFRTLTSPSLVQFSC 360
           +++ +     CS +K++  S+  DGT+ C+ L          R   F     P  VQ  C
Sbjct: 269 SITSLQFSPLCSGSKRYLSSTGADGTI-CFWLWDAGTLKINPRPAKFTERPRPG-VQMIC 326

Query: 361 VALDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +  + G F A G  D +  ++ +     + +  L  H   V S+ FS   TS R  S S
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSN--TSNRFVSGS 384

Query: 420 WDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEI 457
            DGT R+W    RE         S  L +A RP G+ +
Sbjct: 385 RDGTARIWQFKRRE-------WKSILLDMATRPAGQNL 415



 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 4/119 (3%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H ++V  VT     +   + S D  V+ +     R   TL   +  + S +A++      
Sbjct: 182 HLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHA-AEISDMAVNYENTMI 240

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR--LASASWDGTVRLW 427
           AAG  D   I VW ++    L VL GH A ++SL FSP  + ++  L+S   DGT+  W
Sbjct: 241 AAGSCDKM-IRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFW 298



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 4/120 (3%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+ +   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMI 240

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVW 383
            + S D  +R + L        L     S + +QFS +   S     + G       ++W
Sbjct: 241 AAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLW 300



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 49/179 (27%), Positives = 76/179 (42%), Gaps = 26/179 (14%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG----FCFVTFHEHKATVSGVTCSANKKF 326
           + M C ++S  G+ + TG  D  ++V+   +G       + FH  K  V  +  S     
Sbjct: 322 VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDK--VDSIQFSNTSNR 379

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTL-----TSPS------------LVQFSCVALDSSGEF 369
           FVS S DGT R +   R R ++++     T P+             ++ + VA D     
Sbjct: 380 FVSGSRDGTARIWQFKR-REWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNT 438

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
                 ++  + VW+   G+L+ VL GHE  V  L   P      L SA  DG V +WD
Sbjct: 439 VITAVNNM-TLKVWNSYTGQLIHVLMGHEDEVFVLEPHP-FDPRVLFSAGHDGNVIVWD 495



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 18/71 (25%), Positives = 34/71 (47%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           ++ C  +S+    LA GS D   +++     +   +  L  HTDK+  + F   S   ++
Sbjct: 323 QMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVS 382

Query: 86  VSRNGQLCLWE 96
            SR+G   +W+
Sbjct: 383 GSRDGTARIWQ 393



 Score = 34.7 bits (76), Expect = 1.2
 Identities = 25/106 (23%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++    +       LIH L   E  +  +   P    + F
Sbjct: 424 KMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLF 483

Query: 245 ACPNIGQLLVWEW------QSEQYVMKQQGHSLDMTCLAYSPDGLH 284
           +  + G ++VW+       +S   +++ QGH     C   SPDG H
Sbjct: 484 SAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKC-SPDGQH 528


>AJ303102-1|CAC83118.1| 1821|Homo sapiens WD repeat domain 11
           protein protein.
          Length = 1821

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 54/218 (24%), Positives = 91/218 (41%), Gaps = 25/218 (11%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GH+ +++ +A + +   +  G  D  ++VW             H A
Sbjct: 209 IWATDDGRLLATLRGHAAEISDMAVNYENTMIAAGSCDKMIRVWCLRTCAPLAVLQGHSA 268

Query: 314 TVSGV----TCSANKKFFVSSSLDGTVRCYDL---------TRYRNFRTLTSPSLVQFSC 360
           +++ +     CS +K++  S+  DGT+ C+ L          R   F     P  VQ  C
Sbjct: 269 SITSLQFSPLCSGSKRYLSSTGADGTI-CFWLWDAGTLKINPRPAKFTERPRPG-VQMIC 326

Query: 361 VALDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
            +  + G F A G  D +  ++ +     + +  L  H   V S+ FS   TS R  S S
Sbjct: 327 SSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSN--TSNRFVSGS 384

Query: 420 WDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEI 457
            DGT R+W    RE         S  L +A RP G+ +
Sbjct: 385 RDGTARIWQFKRRE-------WKSILLDMATRPAGQNL 415



 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 36/119 (30%), Positives = 56/119 (47%), Gaps = 4/119 (3%)

Query: 311 HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFC 370
           H ++V  VT     +   + S D  V+ +     R   TL   +  + S +A++      
Sbjct: 182 HLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHA-AEISDMAVNYENTMI 240

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR--LASASWDGTVRLW 427
           AAG  D   I VW ++    L VL GH A ++SL FSP  + ++  L+S   DGT+  W
Sbjct: 241 AAGSCDKM-IRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFW 298



 Score = 44.4 bits (100), Expect = 0.001
 Identities = 28/120 (23%), Positives = 46/120 (38%), Gaps = 4/120 (3%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+ +   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 181 GHLSSVYCVTFDRTGRRIFTGSDDCLVKIWATDDGRLLATLRGHAAEISDMAVNYENTMI 240

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVW 383
            + S D  +R + L        L     S + +QFS +   S     + G       ++W
Sbjct: 241 AAGSCDKMIRVWCLRTCAPLAVLQGHSASITSLQFSPLCSGSKRYLSSTGADGTICFWLW 300



 Score = 43.2 bits (97), Expect = 0.003
 Identities = 49/179 (27%), Positives = 76/179 (42%), Gaps = 26/179 (14%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG----FCFVTFHEHKATVSGVTCSANKKF 326
           + M C ++S  G+ + TG  D  ++V+   +G       + FH  K  V  +  S     
Sbjct: 322 VQMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDK--VDSIQFSNTSNR 379

Query: 327 FVSSSLDGTVRCYDLTRYRNFRTL-----TSPS------------LVQFSCVALDSSGEF 369
           FVS S DGT R +   R R ++++     T P+             ++ + VA D     
Sbjct: 380 FVSGSRDGTARIWQFKR-REWKSILLDMATRPAGQNLQGIEDKITKMKVTMVAWDRHDNT 438

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
                 ++  + VW+   G+L+ VL GHE  V  L   P      L SA  DG V +WD
Sbjct: 439 VITAVNNM-TLKVWNSYTGQLIHVLMGHEDEVFVLEPHP-FDPRVLFSAGHDGNVIVWD 495



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 18/71 (25%), Positives = 34/71 (47%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLIT 85
           ++ C  +S+    LA GS D   +++     +   +  L  HTDK+  + F   S   ++
Sbjct: 323 QMICSSFSAGGMFLATGSTDHIIRVYFFGSGQPEKISELEFHTDKVDSIQFSNTSNRFVS 382

Query: 86  VSRNGQLCLWE 96
            SR+G   +W+
Sbjct: 383 GSRDGTARIWQ 393



 Score = 34.7 bits (76), Expect = 1.2
 Identities = 25/106 (23%), Positives = 47/106 (44%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++    +       LIH L   E  +  +   P    + F
Sbjct: 424 KMKVTMVAWDRHDNTVITAVNNMTLKVWNSYTGQLIHVLMGHEDEVFVLEPHPFDPRVLF 483

Query: 245 ACPNIGQLLVWEW------QSEQYVMKQQGHSLDMTCLAYSPDGLH 284
           +  + G ++VW+       +S   +++ QGH     C   SPDG H
Sbjct: 484 SAGHDGNVIVWDLARGVKIRSYFNMIEGQGHGAVFDCKC-SPDGQH 528


>AF083217-1|AAD45865.1|  943|Homo sapiens WD repeat protein WDR3
           protein.
          Length = 943

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 43/184 (23%), Positives = 76/184 (41%), Gaps = 4/184 (2%)

Query: 245 ACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           A P    + +W+ +  + ++  QG   ++TCL  SPDGLH+  G  DG +++++  +G  
Sbjct: 40  AVPACEHVFIWDLRKGEKILILQGLKQEVTCLCPSPDGLHLAVGYEDGSIRIFSLLSGEG 99

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            VTF+ HKA ++ +          S S D  +  +D+        L          + L 
Sbjct: 100 NVTFNGHKAAITTLKYDQLGGRLASGSKDTDIIVWDVINESGLYRLKGHKDAITQALFLR 159

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
                    G+D   +  W +      + + GH   V  L         RL + + D  +
Sbjct: 160 EK-NLLVTSGKDTM-VKWWDLDTQHCFKTMVGHRTEVWGLVL--LSEEKRLITGASDSEL 215

Query: 425 RLWD 428
           R+WD
Sbjct: 216 RVWD 219



 Score = 56.0 bits (129), Expect = 5e-07
 Identities = 35/160 (21%), Positives = 70/160 (43%), Gaps = 3/160 (1%)

Query: 217 VNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCL 276
           V    TL + E  +  +S SP    +A +  +   + ++   + ++ +   GH L + C+
Sbjct: 540 VKQTRTLQLDED-VLCVSYSPNQKLLAVSLLDC-TVKIFYVDTLKFFLSLYGHKLPVICM 597

Query: 277 AYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTV 336
             S DG  + TG  D  VK+W    G C  +   H  +V  +        F ++  D  +
Sbjct: 598 DISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVPKSHLFFTAGKDHKI 657

Query: 337 RCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQD 376
           + +D  ++ + +TL      +  C+A+  SG++  +   D
Sbjct: 658 KQWDADKFEHIQTLEGHH-QEIWCLAVSPSGDYVVSSSHD 696



 Score = 48.0 bits (109), Expect = 1e-04
 Identities = 53/244 (21%), Positives = 107/244 (43%), Gaps = 18/244 (7%)

Query: 197 NKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ-LLVW 255
           ++ +V G  +G   L+++   NL+ T+   +  + S+S+SP  D   F      + +  W
Sbjct: 466 DRQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSP--DQRGFVTGGADKSVKFW 523

Query: 256 EWQ-------SEQYVMKQQGHSL----DMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC 304
           +++       +++ +  +Q  +L    D+ C++YSP+   +     D  VK++       
Sbjct: 524 DFELVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLKF 583

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
           F++ + HK  V  +  S +     + S D  V+ + L      ++L +          + 
Sbjct: 584 FLSLYGHKLPVICMDISHDGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVP 643

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
            S  F  AG     +I  W     + ++ L GH   +  LA SP  +   + S+S D ++
Sbjct: 644 KSHLFFTAGKD--HKIKQWDADKFEHIQTLEGHHQEIWCLAVSP--SGDYVVSSSHDKSL 699

Query: 425 RLWD 428
           RLW+
Sbjct: 700 RLWE 703



 Score = 46.0 bits (104), Expect = 5e-04
 Identities = 23/90 (25%), Positives = 45/90 (50%)

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           ++VW+  +E  + + +GH   +T   +  +   +VT G D  VK W+     CF T   H
Sbjct: 131 IIVWDVINESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDTQHCFKTMVGH 190

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
           +  V G+   + +K  ++ + D  +R +D+
Sbjct: 191 RTEVWGLVLLSEEKRLITGASDSELRVWDI 220



 Score = 39.5 bits (88), Expect = 0.043
 Identities = 16/63 (25%), Positives = 31/63 (49%)

Query: 238 PGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
           P   + F      ++  W+    +++   +GH  ++ CLA SP G +VV+   D  +++W
Sbjct: 643 PKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVVSSSHDKSLRLW 702

Query: 298 NTT 300
             T
Sbjct: 703 ERT 705



 Score = 38.3 bits (85), Expect = 0.098
 Identities = 52/270 (19%), Positives = 101/270 (37%), Gaps = 15/270 (5%)

Query: 223 LSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG 282
           ++I  HR    ++S   D IA        + +W   + Q +           C  + P  
Sbjct: 409 ITIGGHRSDVRTLSFSSDNIAVLSAAADSIKIWNRSTLQCIRTMTCEYA--LCSFFVPGD 466

Query: 283 LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD-- 340
             VV G   GK+++++  +G    T   H   +  ++ S +++ FV+   D +V+ +D  
Sbjct: 467 RQVVIGTKTGKLQLYDLASGNLLETIDAHDGALWSMSLSPDQRGFVTGGADKSVKFWDFE 526

Query: 341 LTRYRNF--------RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLE 392
           L +  N         +T T        CV+   + +  A    D   + ++ +   K   
Sbjct: 527 LVKDENSTQKRLSVKQTRTLQLDEDVLCVSYSPNQKLLAVSLLDC-TVKIFYVDTLKFFL 585

Query: 393 VLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRP 452
            L GH+ PV  +  S       +A+ S D  V++W     +        +   + + F P
Sbjct: 586 SLYGHKLPVICMDISH--DGALIATGSADRNVKIWGLDFGDCHKSLFAHDDSVMYLQFVP 643

Query: 453 DGEEIAVSTLDGNITFFEPSTCEQTGSVEG 482
                  +  D  I  ++    E   ++EG
Sbjct: 644 KSHLFFTAGKDHKIKQWDADKFEHIQTLEG 673



 Score = 34.7 bits (76), Expect = 1.2
 Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 2/70 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           +T L +      LA GSKDT   +  V  +    +Y L GH D I    F R+   L+T 
Sbjct: 110 ITTLKYDQLGGRLASGSKDTDIIVWDV--INESGLYRLKGHKDAITQALFLREKNLLVTS 167

Query: 87  SRNGQLCLWE 96
            ++  +  W+
Sbjct: 168 GKDTMVKWWD 177



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 39/170 (22%), Positives = 70/170 (41%), Gaps = 6/170 (3%)

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
           F      K  +  VT    K  +V+      V  +DL +      L      + +C+   
Sbjct: 16  FGVIGSQKGNIVFVTLRGEKGRYVAVPACEHVFIWDLRKGEKILILQGLKQ-EVTCLCPS 74

Query: 365 SSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTV 424
             G   A G +D   I ++S+  G+      GH+A +++L +       RLAS S D  +
Sbjct: 75  PDGLHLAVGYEDG-SIRIFSLLSGEGNVTFNGHKAAITTLKYDQL--GGRLASGSKDTDI 131

Query: 425 RLWDCIDREVQCEPIRLNSDAL-QVAFRPDGEEIAVSTLDGNITFFEPST 473
            +WD I+ E     ++ + DA+ Q  F  +   +  S  D  + +++  T
Sbjct: 132 IVWDVIN-ESGLYRLKGHKDAITQALFLREKNLLVTSGKDTMVKWWDLDT 180



 Score = 32.3 bits (70), Expect = 6.5
 Identities = 20/75 (26%), Positives = 32/75 (42%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H   +  L + P      T G D K+K W+        T   H   +  +  S +  + V
Sbjct: 632 HDDSVMYLQFVPKSHLFFTAGKDHKIKQWDADKFEHIQTLEGHHQEIWCLAVSPSGDYVV 691

Query: 329 SSSLDGTVRCYDLTR 343
           SSS D ++R ++ TR
Sbjct: 692 SSSHDKSLRLWERTR 706



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 8/122 (6%)

Query: 25  DEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLI 84
           ++V C+ +S   +LLAV   D T KI  V+ L+     SL GH   +I +        + 
Sbjct: 550 EDVLCVSYSPNQKLLAVSLLDCTVKIFYVDTLK--FFLSLYGHKLPVICMDISHDGALIA 607

Query: 85  TVSRNGQLCLWEASI-DADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEKEYDS 143
           T S +  + +W     D  +     DD+     + LQ        F A  D  K K++D+
Sbjct: 608 TGSADRNVKIWGLDFGDCHKSLFAHDDSV----MYLQFVPKSHLFFTAGKD-HKIKQWDA 662

Query: 144 DR 145
           D+
Sbjct: 663 DK 664


>BC025392-1|AAH25392.1|  620|Homo sapiens WD repeat domain 16
           protein.
          Length = 620

 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 63/248 (25%), Positives = 102/248 (41%), Gaps = 16/248 (6%)

Query: 221 HTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSP 280
           H +       S IS    G   AFA P  G+L+        YV+    H + +T +A + 
Sbjct: 378 HGIDFMRDGKSIISAWNDGKIRAFA-PETGRLM--------YVINN-AHRIGVTAIATTS 427

Query: 281 DGLHVVTGGFDGKVKVWNT--TNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRC 338
           D   V++GG +G+V+VW              EHK++VS +    N +  V++S DGT   
Sbjct: 428 DCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCII 487

Query: 339 YDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE 398
           +DL R R  + + + +L  F CV            G D  +I  W +  G ++  L G  
Sbjct: 488 WDLVRLRRNQMILANTL--FQCVCYHPEEFQIITSGTD-RKIAYWEVFDGTVIRELEG-S 543

Query: 399 APVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIA 458
              S      T       +   D  V++WD  + EV    +  + +  ++   P  + I 
Sbjct: 544 LSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIV 603

Query: 459 VSTLDGNI 466
             + DG I
Sbjct: 604 SVSADGAI 611



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 43/179 (24%), Positives = 80/179 (44%), Gaps = 6/179 (3%)

Query: 294 VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSP 353
           ++VW+T++    +       T  G+    + K  +S+  DG +R +     R    + + 
Sbjct: 356 IRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINNA 415

Query: 354 SLVQFSCVALDSSGEFCAAGGQDVFEIFVWSI--KFGKLLEVLGGHEAPVSSLAFSPTLT 411
             +  + +A  S  +   +GG +  E+ VW I  +  KL E L  H++ VS +       
Sbjct: 416 HRIGVTAIATTSDCKRVISGGGE-GEVRVWQIGCQTQKLEEALKEHKSSVSCIRVK--RN 472

Query: 412 STRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           +    +AS DGT  +WD + R  + + I  N+    V + P+  +I  S  D  I ++E
Sbjct: 473 NEECVTASTDGTCIIWDLV-RLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWE 530



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 9/120 (7%)

Query: 359 SCVALDSSGEFCAAGGQDVF-----EIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTST 413
           SC+A+  SGE+ A+G Q  F     +I +W  K  +LL  L  H+  + +LAFSP     
Sbjct: 68  SCLAISRSGEYIASG-QVTFMGFKVDIILWDYKNRELLARLSLHKGKIEALAFSPNDLYL 126

Query: 414 RLASASWDGTVRLWDCIDREVQC-EPIR-LN-SDALQVAFRPDGEEIAVSTLDGNITFFE 470
                  DG+V +W    R+  C  P   LN  +A  V F    +E+ ++  +G I  +E
Sbjct: 127 VSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATNVIFSRCRDEMFMTAGNGTIRVWE 186



 Score = 37.5 bits (83), Expect = 0.17
 Identities = 27/144 (18%), Positives = 59/144 (40%), Gaps = 2/144 (1%)

Query: 235 VSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKV 294
           V P G    FA      + VW   S + +++    ++    + +  DG  +++   DGK+
Sbjct: 339 VFPFGTAELFATCAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKI 398

Query: 295 KVWNTTNG-FCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTS 352
           + +    G   +V  + H+  V+ +  +++ K  +S   +G VR + +  + +       
Sbjct: 399 RAFAPETGRLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALK 458

Query: 353 PSLVQFSCVALDSSGEFCAAGGQD 376
                 SC+ +  + E C     D
Sbjct: 459 EHKSSVSCIRVKRNNEECVTASTD 482



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 20/77 (25%), Positives = 45/77 (58%), Gaps = 6/77 (7%)

Query: 228 HRISSISVSPPGDWIAFACPN-IG---QLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGL 283
           + +S +++S  G++IA      +G    +++W++++ + + +   H   +  LA+SP+ L
Sbjct: 65  NNVSCLAISRSGEYIASGQVTFMGFKVDIILWDYKNRELLARLSLHKGKIEALAFSPNDL 124

Query: 284 HVVT--GGFDGKVKVWN 298
           ++V+  G  DG V VW+
Sbjct: 125 YLVSLGGPDDGSVVVWS 141



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 7/84 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTG-----GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCS 321
           QGH  +++CLA S  G ++ +G     GF   + +W+  N         HK  +  +  S
Sbjct: 61  QGHGNNVSCLAISRSGEYIASGQVTFMGFKVDIILWDYKNRELLARLSLHKGKIEALAFS 120

Query: 322 ANKKFFVS--SSLDGTVRCYDLTR 343
            N  + VS     DG+V  + + +
Sbjct: 121 PNDLYLVSLGGPDDGSVVVWSIAK 144



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 4/109 (3%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSIS-EHRISSISVSPPGDWIAFACPNI 249
           V YH E   ++T  +       E+ D  +I  L  S    I+ + ++  G  + F     
Sbjct: 508 VCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEG--VHFVTGGN 565

Query: 250 GQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
             L+ VW++   +      GHS ++T +  SP   ++V+   DG +  W
Sbjct: 566 DHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 614


>AK222576-1|BAD96296.1|  421|Homo sapiens WD SOCS-box protein 1
           isoform 1 variant protein.
          Length = 421

 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 59/241 (24%), Positives = 100/241 (41%), Gaps = 13/241 (5%)

Query: 192 QYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ 251
           Q H+  KL+        F LH   +V    +L +          + P + I   C +I  
Sbjct: 53  QGHRTVKLVPWSQCLQNFLLHGTKNVTNSSSLRLPRQNSDGGQKNKPREHI-IDCGDI-- 109

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTC--LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
             VW       V ++Q   +++      +  D L + TG  +G++K+W+   G   +   
Sbjct: 110 --VWSLAFGSSVPEKQSRCVNIEWHRFRFGQDQLLLATGLNNGRIKIWDVYTGKLLLNLV 167

Query: 310 EHKATVSGVTCSAN-KKFFVSSSLDGTVRCYDLTRYRN-FRTLTSPSLVQFSCVALDSSG 367
           +H   V  +T + +     VS+S D T+R +DL    N  + L       +SC     S 
Sbjct: 168 DHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMMKVLRGHQNWVYSCAFSPDSS 227

Query: 368 EFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
             C+ G      +F+W++    ++  L G    V +  FSP      LA+AS+D  V +W
Sbjct: 228 MLCSVGASKA--VFLWNMDKYTMIRKLEGRHHDVVACDFSP--DGALLATASYDTRVYIW 283

Query: 428 D 428
           D
Sbjct: 284 D 284



 Score = 51.2 bits (117), Expect = 1e-05
 Identities = 56/238 (23%), Positives = 98/238 (41%), Gaps = 23/238 (9%)

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG-LHVVTGGFDGKVKVWNTTN-GFCF 305
           N G++ +W+  + + ++    H+  +  L ++PDG L +V+   D  ++VW+  + G   
Sbjct: 148 NNGRIKIWDVYTGKLLLNLVDHTEVVRDLTFAPDGSLILVSASRDKTLRVWDLKDDGNMM 207

Query: 306 VTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS 365
                H+  V     S +     S      V  +++ +Y   R L        +C     
Sbjct: 208 KVLRGHQNWVYSCAFSPDSSMLCSVGASKAVFLWNMDKYTMIRKLEGRHHDVVAC-DFSP 266

Query: 366 SGEFCAAGGQDVFEIFVWS-------IKFGKLLE------VLGGHEAPVSSLAFSPTLTS 412
            G   A    D   +++W        ++FG L          G ++  V S++FS     
Sbjct: 267 DGALLATASYDT-RVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSFSHD--G 323

Query: 413 TRLASASWDGTVRLWDCI-DREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
             +AS + D  VR W    D  VQ  P+   S+ L  AF  DG  +A  T DG++ F+
Sbjct: 324 LHVASLADDKMVRFWRIDEDYPVQVAPL---SNGLCCAFSTDGSVLAAGTHDGSVYFW 378



 Score = 44.0 bits (99), Expect = 0.002
 Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 5/92 (5%)

Query: 382 VWSIKF-GKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
           VW +K  G +++VL GH+  V S AFSP   S+ L S      V LW+ +D+      + 
Sbjct: 197 VWDLKDDGNMMKVLRGHQNWVYSCAFSPD--SSMLCSVGASKAVFLWN-MDKYTMIRKLE 253

Query: 441 -LNSDALQVAFRPDGEEIAVSTLDGNITFFEP 471
             + D +   F PDG  +A ++ D  +  ++P
Sbjct: 254 GRHHDVVACDFSPDGALLATASYDTRVYIWDP 285



 Score = 43.6 bits (98), Expect = 0.003
 Identities = 45/181 (24%), Positives = 73/181 (40%), Gaps = 16/181 (8%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVM--KQQGHSLDM 273
           D N++  L   ++ + S + SP    +   C       V+ W  ++Y M  K +G   D+
Sbjct: 203 DGNMMKVLRGHQNWVYSCAFSPDSSML---CSVGASKAVFLWNMDKYTMIRKLEGRHHDV 259

Query: 274 TCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF-HEHKATVSGVTCSANKKFF--VSS 330
               +SPDG  + T  +D +V +W+  NG   + F H            AN ++   VS 
Sbjct: 260 VACDFSPDGALLATASYDTRVYIWDPHNGDILMEFGHLFPPPTPIFAGGANDRWVRSVSF 319

Query: 331 SLDGT-VRCYDLTRYRNFRTLTSPSLVQFS------CVALDSSGEFCAAGGQDVFEIFVW 383
           S DG  V      +   F  +     VQ +      C A  + G   AAG  D   ++ W
Sbjct: 320 SHDGLHVASLADDKMVRFWRIDEDYPVQVAPLSNGLCCAFSTDGSVLAAGTHD-GSVYFW 378

Query: 384 S 384
           +
Sbjct: 379 A 379


>AK094847-1|BAC04435.1|  630|Homo sapiens protein ( Homo sapiens
           cDNA FLJ37528 fis, clone BRCAN2012408. ).
          Length = 630

 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 63/248 (25%), Positives = 102/248 (41%), Gaps = 16/248 (6%)

Query: 221 HTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSP 280
           H +       S IS    G   AFA P  G+L+        YV+    H + +T +A + 
Sbjct: 388 HGIDFMRDGKSIISAWNDGKIRAFA-PETGRLM--------YVINN-AHRIGVTAIATTS 437

Query: 281 DGLHVVTGGFDGKVKVWNT--TNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRC 338
           D   V++GG +G+V+VW              EHK++VS +    N +  V++S DGT   
Sbjct: 438 DCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCII 497

Query: 339 YDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE 398
           +DL R R  + + + +L  F CV            G D  +I  W +  G ++  L G  
Sbjct: 498 WDLVRLRRNQMILANTL--FQCVCYHPEEFQIITSGTD-RKIAYWEVFDGTVIRELEG-S 553

Query: 399 APVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIA 458
              S      T       +   D  V++WD  + EV    +  + +  ++   P  + I 
Sbjct: 554 LSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIV 613

Query: 459 VSTLDGNI 466
             + DG I
Sbjct: 614 SVSADGAI 621



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 43/179 (24%), Positives = 80/179 (44%), Gaps = 6/179 (3%)

Query: 294 VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSP 353
           ++VW+T++    +       T  G+    + K  +S+  DG +R +     R    + + 
Sbjct: 366 IRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINNA 425

Query: 354 SLVQFSCVALDSSGEFCAAGGQDVFEIFVWSI--KFGKLLEVLGGHEAPVSSLAFSPTLT 411
             +  + +A  S  +   +GG +  E+ VW I  +  KL E L  H++ VS +       
Sbjct: 426 HRIGVTAIATTSDCKRVISGGGE-GEVRVWQIGCQTQKLEEALKEHKSSVSCIRVK--RN 482

Query: 412 STRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           +    +AS DGT  +WD + R  + + I  N+    V + P+  +I  S  D  I ++E
Sbjct: 483 NEECVTASTDGTCIIWDLV-RLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWE 540



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 9/120 (7%)

Query: 359 SCVALDSSGEFCAAGGQDVF-----EIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTST 413
           SC+A+  SGE+ A+G Q  F     +I +W  K  +LL  L  H+  + +LAFSP     
Sbjct: 78  SCLAISRSGEYIASG-QVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDLYL 136

Query: 414 RLASASWDGTVRLWDCIDREVQC-EPIR-LN-SDALQVAFRPDGEEIAVSTLDGNITFFE 470
                  DG+V +W    R+  C  P   LN  +A  V F    +E+ ++  +G I  +E
Sbjct: 137 VSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATNVIFSRCRDEMFMTAGNGTIRVWE 196



 Score = 37.5 bits (83), Expect = 0.17
 Identities = 27/144 (18%), Positives = 59/144 (40%), Gaps = 2/144 (1%)

Query: 235 VSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKV 294
           V P G    FA      + VW   S + +++    ++    + +  DG  +++   DGK+
Sbjct: 349 VFPFGTAELFATCAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKI 408

Query: 295 KVWNTTNG-FCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTS 352
           + +    G   +V  + H+  V+ +  +++ K  +S   +G VR + +  + +       
Sbjct: 409 RAFAPETGRLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALK 468

Query: 353 PSLVQFSCVALDSSGEFCAAGGQD 376
                 SC+ +  + E C     D
Sbjct: 469 EHKSSVSCIRVKRNNEECVTASTD 492



 Score = 37.1 bits (82), Expect = 0.23
 Identities = 19/77 (24%), Positives = 43/77 (55%), Gaps = 6/77 (7%)

Query: 228 HRISSISVSPPGDWIAFACPNI----GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGL 283
           + +S +++S  G++IA            +++W++++ + + +   H   +  LA+SP+ L
Sbjct: 75  NNVSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDL 134

Query: 284 HVVT--GGFDGKVKVWN 298
           ++V+  G  DG V VW+
Sbjct: 135 YLVSLGGPDDGSVVVWS 151



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 7/84 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTG-----GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCS 321
           QGH  +++CLA S  G ++ +G     GF   + +W+  N         HK  +  +  S
Sbjct: 71  QGHGNNVSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFS 130

Query: 322 ANKKFFVS--SSLDGTVRCYDLTR 343
            N  + VS     DG+V  + + +
Sbjct: 131 PNDLYLVSLGGPDDGSVVVWSIAK 154



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 4/109 (3%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSIS-EHRISSISVSPPGDWIAFACPNI 249
           V YH E   ++T  +       E+ D  +I  L  S    I+ + ++  G  + F     
Sbjct: 518 VCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEG--VHFVTGGN 575

Query: 250 GQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
             L+ VW++   +      GHS ++T +  SP   ++V+   DG +  W
Sbjct: 576 DHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 624


>AK074435-1|BAB85083.1|  412|Homo sapiens protein ( Homo sapiens
           cDNA FLJ23855 fis, clone LNG06370. ).
          Length = 412

 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 63/248 (25%), Positives = 102/248 (41%), Gaps = 16/248 (6%)

Query: 221 HTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSP 280
           H +       S IS    G   AFA P  G+L+        YV+    H + +T +A + 
Sbjct: 170 HGIDFMRDGKSIISAWNDGKIRAFA-PETGRLM--------YVINN-AHRIGVTAIATTS 219

Query: 281 DGLHVVTGGFDGKVKVWNT--TNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRC 338
           D   V++GG +G+V+VW              EHK++VS +    N +  V++S DGT   
Sbjct: 220 DCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCII 279

Query: 339 YDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE 398
           +DL R R  + + + +L  F CV            G D  +I  W +  G ++  L G  
Sbjct: 280 WDLVRLRRNQMILANTL--FQCVCYHPEEFQIITSGTD-RKIAYWEVFDGTVIRELEG-S 335

Query: 399 APVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIA 458
              S      T       +   D  V++WD  + EV    +  + +  ++   P  + I 
Sbjct: 336 LSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIV 395

Query: 459 VSTLDGNI 466
             + DG I
Sbjct: 396 SVSADGAI 403



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 43/179 (24%), Positives = 80/179 (44%), Gaps = 6/179 (3%)

Query: 294 VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSP 353
           ++VW+T++    +       T  G+    + K  +S+  DG +R +     R    + + 
Sbjct: 148 IRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINNA 207

Query: 354 SLVQFSCVALDSSGEFCAAGGQDVFEIFVWSI--KFGKLLEVLGGHEAPVSSLAFSPTLT 411
             +  + +A  S  +   +GG +  E+ VW I  +  KL E L  H++ VS +       
Sbjct: 208 HRIGVTAIATTSDCKRVISGGGE-GEVRVWQIGCQTQKLEEALKEHKSSVSCIRVK--RN 264

Query: 412 STRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           +    +AS DGT  +WD + R  + + I  N+    V + P+  +I  S  D  I ++E
Sbjct: 265 NEECVTASTDGTCIIWDLV-RLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWE 322



 Score = 37.5 bits (83), Expect = 0.17
 Identities = 27/144 (18%), Positives = 59/144 (40%), Gaps = 2/144 (1%)

Query: 235 VSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKV 294
           V P G    FA      + VW   S + +++    ++    + +  DG  +++   DGK+
Sbjct: 131 VFPFGTAELFATCAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKI 190

Query: 295 KVWNTTNG-FCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTS 352
           + +    G   +V  + H+  V+ +  +++ K  +S   +G VR + +  + +       
Sbjct: 191 RAFAPETGRLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALK 250

Query: 353 PSLVQFSCVALDSSGEFCAAGGQD 376
                 SC+ +  + E C     D
Sbjct: 251 EHKSSVSCIRVKRNNEECVTASTD 274



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 4/109 (3%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSIS-EHRISSISVSPPGDWIAFACPNI 249
           V YH E   ++T  +       E+ D  +I  L  S    I+ + ++  G  + F     
Sbjct: 300 VCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEG--VHFVTGGN 357

Query: 250 GQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
             L+ VW++   +      GHS ++T +  SP   ++V+   DG +  W
Sbjct: 358 DHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 406


>AB065281-1|BAB83743.1|  620|Homo sapiens WDR16 protein.
          Length = 620

 Score = 63.7 bits (148), Expect = 2e-09
 Identities = 63/248 (25%), Positives = 102/248 (41%), Gaps = 16/248 (6%)

Query: 221 HTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSP 280
           H +       S IS    G   AFA P  G+L+        YV+    H + +T +A + 
Sbjct: 378 HGIDFMRDGKSIISAWNDGKIRAFA-PETGRLM--------YVINN-AHRIGVTAIATTS 427

Query: 281 DGLHVVTGGFDGKVKVWNT--TNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRC 338
           D   V++GG +G+V+VW              EHK++VS +    N +  V++S DGT   
Sbjct: 428 DCKRVISGGGEGEVRVWQIGCQTQKLEEALKEHKSSVSCIRVKRNNEECVTASTDGTCII 487

Query: 339 YDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHE 398
           +DL R R  + + + +L  F CV            G D  +I  W +  G ++  L G  
Sbjct: 488 WDLVRLRRNQMILANTL--FQCVCYHPEEFQIITSGTD-RKIAYWEVFDGTVIRELEG-S 543

Query: 399 APVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIA 458
              S      T       +   D  V++WD  + EV    +  + +  ++   P  + I 
Sbjct: 544 LSGSINGMDITQEGVHFVTGGNDHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIV 603

Query: 459 VSTLDGNI 466
             + DG I
Sbjct: 604 SVSADGAI 611



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 43/179 (24%), Positives = 80/179 (44%), Gaps = 6/179 (3%)

Query: 294 VKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSP 353
           ++VW+T++    +       T  G+    + K  +S+  DG +R +     R    + + 
Sbjct: 356 IRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKIRAFAPETGRLMYVINNA 415

Query: 354 SLVQFSCVALDSSGEFCAAGGQDVFEIFVWSI--KFGKLLEVLGGHEAPVSSLAFSPTLT 411
             +  + +A  S  +   +GG +  E+ VW I  +  KL E L  H++ VS +       
Sbjct: 416 HRIGVTAIATTSDCKRVISGGGE-GEVRVWQIGCQTQKLEEALKEHKSSVSCIRVK--RN 472

Query: 412 STRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
           +    +AS DGT  +WD + R  + + I  N+    V + P+  +I  S  D  I ++E
Sbjct: 473 NEECVTASTDGTCIIWDLV-RLRRNQMILANTLFQCVCYHPEEFQIITSGTDRKIAYWE 530



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 38/120 (31%), Positives = 58/120 (48%), Gaps = 9/120 (7%)

Query: 359 SCVALDSSGEFCAAGGQDVF-----EIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTST 413
           SC+A+  SGE+ A+G Q  F     +I +W  K  +LL  L  H+  + +LAFSP     
Sbjct: 68  SCLAISRSGEYIASG-QVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDLYL 126

Query: 414 RLASASWDGTVRLWDCIDREVQC-EPIR-LN-SDALQVAFRPDGEEIAVSTLDGNITFFE 470
                  DG+V +W    R+  C  P   LN  +A  V F    +E+ ++  +G I  +E
Sbjct: 127 VSLGGPDDGSVVVWSIAKRDAICGSPAAGLNVGNATNVIFSRCRDEMFMTAGNGTIRVWE 186



 Score = 37.5 bits (83), Expect = 0.17
 Identities = 27/144 (18%), Positives = 59/144 (40%), Gaps = 2/144 (1%)

Query: 235 VSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKV 294
           V P G    FA      + VW   S + +++    ++    + +  DG  +++   DGK+
Sbjct: 339 VFPFGTAELFATCAKKDIRVWHTSSNRELLRITVPNMTCHGIDFMRDGKSIISAWNDGKI 398

Query: 295 KVWNTTNG-FCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL-TRYRNFRTLTS 352
           + +    G   +V  + H+  V+ +  +++ K  +S   +G VR + +  + +       
Sbjct: 399 RAFAPETGRLMYVINNAHRIGVTAIATTSDCKRVISGGGEGEVRVWQIGCQTQKLEEALK 458

Query: 353 PSLVQFSCVALDSSGEFCAAGGQD 376
                 SC+ +  + E C     D
Sbjct: 459 EHKSSVSCIRVKRNNEECVTASTD 482



 Score = 37.1 bits (82), Expect = 0.23
 Identities = 19/77 (24%), Positives = 43/77 (55%), Gaps = 6/77 (7%)

Query: 228 HRISSISVSPPGDWIAFACPNI----GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGL 283
           + +S +++S  G++IA            +++W++++ + + +   H   +  LA+SP+ L
Sbjct: 65  NNVSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFSPNDL 124

Query: 284 HVVT--GGFDGKVKVWN 298
           ++V+  G  DG V VW+
Sbjct: 125 YLVSLGGPDDGSVVVWS 141



 Score = 36.3 bits (80), Expect = 0.40
 Identities = 22/84 (26%), Positives = 38/84 (45%), Gaps = 7/84 (8%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTG-----GFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCS 321
           QGH  +++CLA S  G ++ +G     GF   + +W+  N         HK  +  +  S
Sbjct: 61  QGHGNNVSCLAISRSGEYIASGQVTFMGFKADIILWDYKNRELLARLSLHKGKIEALAFS 120

Query: 322 ANKKFFVS--SSLDGTVRCYDLTR 343
            N  + VS     DG+V  + + +
Sbjct: 121 PNDLYLVSLGGPDDGSVVVWSIAK 144



 Score = 31.9 bits (69), Expect = 8.5
 Identities = 26/109 (23%), Positives = 47/109 (43%), Gaps = 4/109 (3%)

Query: 191 VQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSIS-EHRISSISVSPPGDWIAFACPNI 249
           V YH E   ++T  +       E+ D  +I  L  S    I+ + ++  G  + F     
Sbjct: 508 VCYHPEEFQIITSGTDRKIAYWEVFDGTVIRELEGSLSGSINGMDITQEG--VHFVTGGN 565

Query: 250 GQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
             L+ VW++   +      GHS ++T +  SP   ++V+   DG +  W
Sbjct: 566 DHLVKVWDYNEGEVTHVGVGHSGNITRIRISPGNQYIVSVSADGAILRW 614


>X70476-1|CAA49900.1|  906|Homo sapiens subunit of coatomer complex
           protein.
          Length = 906

 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 53/248 (21%), Positives = 104/248 (41%), Gaps = 9/248 (3%)

Query: 184 RKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIA 243
           R  ++ +V  H     ++    +G   +       L+ T  + +  + +       +W+ 
Sbjct: 14  RSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVV 73

Query: 244 FACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
               ++ Q+ V+ + + + V   + HS  + C+A  P    ++T   D  +K+W+    +
Sbjct: 74  TGADDM-QIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKW 132

Query: 304 -CFVTFHEHKATVSGVTCS-ANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
            C   F  H   V  +  +  +   F S+SLD T++ + L       TL        +C+
Sbjct: 133 SCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHE-KGVNCI 191

Query: 362 ALDSSGE--FCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
              S G+  +  +G  D   + +W  +    ++ L GH   VS  +F P L    + + S
Sbjct: 192 DYYSGGDKPYLISGADDRL-VKIWDYQNKTCVQTLEGHAQNVSCASFHPELPI--IITGS 248

Query: 420 WDGTVRLW 427
            DGTVR+W
Sbjct: 249 EDGTVRIW 256



 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 5/138 (3%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDG--LH 284
           H +  I ++P  D   FA  ++ + + VW+  S       +GH   + C+ Y   G   +
Sbjct: 143 HYVMQIVINPK-DNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPY 201

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  VK+W+  N  C  T   H   VS  +        ++ S DGTVR +  + Y
Sbjct: 202 LISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTY 261

Query: 345 RNFRTLTSPSLVQFSCVA 362
           R   TL +  + +  CVA
Sbjct: 262 RLESTL-NYGMERVWCVA 278



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 48/252 (19%), Positives = 96/252 (38%), Gaps = 3/252 (1%)

Query: 223 LSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG 282
           L+    R+ S+ + P   W+  +  N G + VW  +++  V   +   L +    +    
Sbjct: 11  LTARSDRVKSVDLHPTEPWMLASLYN-GSVCVWNHETQTLVKTFEVCDLPVRAAKFVARK 69

Query: 283 LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLT 342
             VVTG  D +++V+N         F  H   +  +     + F ++SS D  ++ +D  
Sbjct: 70  NWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWD 129

Query: 343 RYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVS 402
           +  +   +          + ++       A       I VW +        L GHE  V+
Sbjct: 130 KKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVN 189

Query: 403 SLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVA-FRPDGEEIAVST 461
            + +        L S + D  V++WD    +   + +  ++  +  A F P+   I   +
Sbjct: 190 CIDYYSGGDKPYLISGADDRLVKIWD-YQNKTCVQTLEGHAQNVSCASFHPELPIIITGS 248

Query: 462 LDGNITFFEPST 473
            DG +  +  ST
Sbjct: 249 EDGTVRIWHSST 260


>BC000326-1|AAH00326.1|  906|Homo sapiens coatomer protein complex,
           subunit beta 2 (beta prime) protein.
          Length = 906

 Score = 63.3 bits (147), Expect = 3e-09
 Identities = 53/248 (21%), Positives = 104/248 (41%), Gaps = 9/248 (3%)

Query: 184 RKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIA 243
           R  ++ +V  H     ++    +G   +       L+ T  + +  + +       +W+ 
Sbjct: 14  RSDRVKSVDLHPTEPWMLASLYNGSVCVWNHETQTLVKTFEVCDLPVRAAKFVARKNWVV 73

Query: 244 FACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGF 303
               ++ Q+ V+ + + + V   + HS  + C+A  P    ++T   D  +K+W+    +
Sbjct: 74  TGADDM-QIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWDKKW 132

Query: 304 -CFVTFHEHKATVSGVTCS-ANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV 361
            C   F  H   V  +  +  +   F S+SLD T++ + L       TL        +C+
Sbjct: 133 SCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHE-KGVNCI 191

Query: 362 ALDSSGE--FCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
              S G+  +  +G  D   + +W  +    ++ L GH   VS  +F P L    + + S
Sbjct: 192 DYYSGGDKPYLISGADDRL-VKIWDYQNKTCVQTLEGHAQNVSCASFHPELPI--IITGS 248

Query: 420 WDGTVRLW 427
            DGTVR+W
Sbjct: 249 EDGTVRIW 256



 Score = 54.4 bits (125), Expect = 1e-06
 Identities = 38/138 (27%), Positives = 63/138 (45%), Gaps = 5/138 (3%)

Query: 228 HRISSISVSPPGDWIAFACPNIGQLL-VWEWQSEQYVMKQQGHSLDMTCLAYSPDG--LH 284
           H +  I ++P  D   FA  ++ + + VW+  S       +GH   + C+ Y   G   +
Sbjct: 143 HYVMQIVINPK-DNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVNCIDYYSGGDKPY 201

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY 344
           +++G  D  VK+W+  N  C  T   H   VS  +        ++ S DGTVR +  + Y
Sbjct: 202 LISGADDRLVKIWDYQNKTCVQTLEGHAQNVSCASFHPELPIIITGSEDGTVRIWHSSTY 261

Query: 345 RNFRTLTSPSLVQFSCVA 362
           R   TL +  + +  CVA
Sbjct: 262 RLESTL-NYGMERVWCVA 278



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 48/252 (19%), Positives = 96/252 (38%), Gaps = 3/252 (1%)

Query: 223 LSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDG 282
           L+    R+ S+ + P   W+  +  N G + VW  +++  V   +   L +    +    
Sbjct: 11  LTARSDRVKSVDLHPTEPWMLASLYN-GSVCVWNHETQTLVKTFEVCDLPVRAAKFVARK 69

Query: 283 LHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLT 342
             VVTG  D +++V+N         F  H   +  +     + F ++SS D  ++ +D  
Sbjct: 70  NWVVTGADDMQIRVFNYNTLERVHMFEAHSDYIRCIAVHPTQPFILTSSDDMLIKLWDWD 129

Query: 343 RYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVS 402
           +  +   +          + ++       A       I VW +        L GHE  V+
Sbjct: 130 KKWSCSQVFEGHTHYVMQIVINPKDNNQFASASLDRTIKVWQLGSSSPNFTLEGHEKGVN 189

Query: 403 SLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVA-FRPDGEEIAVST 461
            + +        L S + D  V++WD    +   + +  ++  +  A F P+   I   +
Sbjct: 190 CIDYYSGGDKPYLISGADDRLVKIWD-YQNKTCVQTLEGHAQNVSCASFHPELPIIITGS 248

Query: 462 LDGNITFFEPST 473
            DG +  +  ST
Sbjct: 249 EDGTVRIWHSST 260


>AF127799-1|AAP97249.1|  305|Homo sapiens G protein beta
           subunit-like protein protein.
          Length = 305

 Score = 62.9 bits (146), Expect = 4e-09
 Identities = 52/215 (24%), Positives = 94/215 (43%), Gaps = 6/215 (2%)

Query: 254 VWEWQSEQYVMKQ--QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           VW+W+ E+  ++   +GH L +  +  S       +   D  +++ +  NG    +    
Sbjct: 46  VWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLRDLENGKQIKSIDAG 105

Query: 312 KATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCA 371
                 +  S + ++  + +  G V  + +   +   +L +      S +A    G++ A
Sbjct: 106 PVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILS-IAYSPDGKYLA 164

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCID 431
           +G  D   I +++I  GKLL  L GH  P+ SL FSP   S  L +AS DG ++++D   
Sbjct: 165 SGAIDGI-INIFAIATGKLLHTLEGHAMPIRSLTFSP--DSQLLVTASDDGYIKIYDVQH 221

Query: 432 REVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNI 466
             +        S  L VAF PD      S+ D ++
Sbjct: 222 ANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSV 256



 Score = 62.9 bits (146), Expect = 4e-09
 Identities = 40/153 (26%), Positives = 67/153 (43%), Gaps = 1/153 (0%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACP 247
           + ++ Y  + K L +G   G+  +  +    L+HTL      I S++ SP    +  A  
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFAIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210

Query: 248 NIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVT 307
           + G + +++ Q         GH+  +  +A+ PD  H V+   D  VKV +     C  T
Sbjct: 211 D-GYIKIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVRDVGTRTCVHT 269

Query: 308 FHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
           F +H+  V GV  + N    VS   D  +  YD
Sbjct: 270 FFDHQDQVWGVKYNGNGSKIVSVGDDQEIHIYD 302



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 40/167 (23%), Positives = 77/167 (46%), Gaps = 2/167 (1%)

Query: 176 GDAIRNADR-KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSIS 234
           G  I++ D   V    + +  +++ L TG   G   +  +      ++L      I SI+
Sbjct: 96  GKQIKSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIA 155

Query: 235 VSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKV 294
            SP G ++A    + G + ++   + + +   +GH++ +  L +SPD   +VT   DG +
Sbjct: 156 YSPDGKYLASGAID-GIINIFAIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASDDGYI 214

Query: 295 KVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
           K+++  +     T   H + V  V    +   FVSSS D +V+  D+
Sbjct: 215 KIYDVQHANLAGTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVRDV 261



 Score = 49.2 bits (112), Expect = 5e-05
 Identities = 45/202 (22%), Positives = 86/202 (42%), Gaps = 6/202 (2%)

Query: 285 VVTGGFDGKVKVWNTTNGFCFV--TFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLT 342
           VVTG  D  VKVW   +    +  +   H+  V  V  S       SSSLD  +R  DL 
Sbjct: 35  VVTGSLDDLVKVWKWRDERLDLQWSLEGHQLGVVSVDISHTLPIAASSSLDAHIRLRDLE 94

Query: 343 RYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVS 402
             +  +++ +  +  ++ +A     ++ A  G  V ++ ++ ++ GK    L      + 
Sbjct: 95  NGKQIKSIDAGPVDAWT-LAFSPDSQYLAT-GTHVGKVNIFGVESGKKEYSLDTRGKFIL 152

Query: 403 SLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTL 462
           S+A+SP      LAS + DG + ++     ++             + F PD + +  ++ 
Sbjct: 153 SIAYSP--DGKYLASGAIDGIINIFAIATGKLLHTLEGHAMPIRSLTFSPDSQLLVTASD 210

Query: 463 DGNITFFEPSTCEQTGSVEGRS 484
           DG I  ++       G++ G +
Sbjct: 211 DGYIKIYDVQHANLAGTLSGHA 232



 Score = 40.7 bits (91), Expect = 0.018
 Identities = 47/190 (24%), Positives = 80/190 (42%), Gaps = 12/190 (6%)

Query: 302 GFCFVTFHEHKATVSGVTCSANKK----FFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV- 356
           G  F     H   +  V    NKK      V+ SLD  V+ +   ++R+ R     SL  
Sbjct: 6   GILFKQEQAHDDAIWSVAWGTNKKENSETVVTGSLDDLVKVW---KWRDERLDLQWSLEG 62

Query: 357 -QFSCVALDSSGEFCAAGGQDV-FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTR 414
            Q   V++D S     A    +   I +  ++ GK ++ +        +LAFSP   S  
Sbjct: 63  HQLGVVSVDISHTLPIAASSSLDAHIRLRDLENGKQIKSIDAGPVDAWTLAFSPD--SQY 120

Query: 415 LASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFEPSTC 474
           LA+ +  G V ++     + +          L +A+ PDG+ +A   +DG I  F  +T 
Sbjct: 121 LATGTHVGKVNIFGVESGKKEYSLDTRGKFILSIAYSPDGKYLASGAIDGIINIFAIATG 180

Query: 475 EQTGSVEGRS 484
           +   ++EG +
Sbjct: 181 KLLHTLEGHA 190


>X96586-1|CAA65405.1|  917|Homo sapiens FAN protein protein.
          Length = 917

 Score = 62.1 bits (144), Expect = 7e-09
 Identities = 37/145 (25%), Positives = 67/145 (46%), Gaps = 7/145 (4%)

Query: 291 DGKVKVWNTTNGFCFVTFHE-HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT 349
           + K   WN          ++ HK  V+G+T S N     ++S D T++ +        R+
Sbjct: 608 ESKTLAWNNITKLQLHEHYKIHKEAVTGITVSRNGSSVFTTSQDSTLKMFSKESKMLQRS 667

Query: 350 LTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPT 409
           ++  ++   SC+ L        +   +   ++ +SI FG+  + L GH+  VS + +   
Sbjct: 668 ISFSNMALSSCLLLPGDATVITSSWDN--NVYFYSIAFGRRQDTLMGHDDAVSKICWH-- 723

Query: 410 LTSTRLASASWDGTVRLWDCIDREV 434
               RL SASWD TV++W  +  E+
Sbjct: 724 --DNRLYSASWDSTVKVWSGVPAEM 746



 Score = 39.9 bits (89), Expect = 0.032
 Identities = 29/136 (21%), Positives = 55/136 (40%), Gaps = 5/136 (3%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H + +  ++ +     +V+G  +G V +W+ T          H   V     S + +  +
Sbjct: 762 HDVSVDTISLNAASTLLVSGTKEGTVNIWDLTTATLMHQIPCHSGIVCDTAFSPDSRHVL 821

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S+  DG +   D+       ++TS      +C   D  G    +G Q   E+ VW +   
Sbjct: 822 STGTDGCLNVIDVQTGMLISSMTSDE--PQTCFVWD--GNSVLSGSQS-GELLVWDLLGA 876

Query: 389 KLLEVLGGHEAPVSSL 404
           K+ E + GH   V+ +
Sbjct: 877 KISERIQGHTGAVTCI 892



 Score = 37.9 bits (84), Expect = 0.13
 Identities = 52/268 (19%), Positives = 105/268 (39%), Gaps = 17/268 (6%)

Query: 225 ISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLH 284
           I +  ++ I+VS  G  + F       L ++  +S+         ++ ++     P    
Sbjct: 628 IHKEAVTGITVSRNGSSV-FTTSQDSTLKMFSKESKMLQRSISFSNMALSSCLLLPGDAT 686

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL--- 341
           V+T  +D  V  ++   G    T   H   VS +    N+ +  S+S D TV+ +     
Sbjct: 687 VITSSWDNNVYFYSIAFGRRQDTLMGHDDAVSKICWHDNRLY--SASWDSTVKVWSGVPA 744

Query: 342 ----TRYRNFRTLTSPSL-VQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGG 396
               T+  +F  L      V    ++L+++     +G ++   + +W +    L+  +  
Sbjct: 745 EMPGTKRHHFDLLAELEHDVSVDTISLNAASTLLVSGTKEG-TVNIWDLTTATLMHQIPC 803

Query: 397 HEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEE 456
           H   V   AFSP   S  + S   DG + +   ID +       + SD  Q  F  DG  
Sbjct: 804 HSGIVCDTAFSP--DSRHVLSTGTDGCLNV---IDVQTGMLISSMTSDEPQTCFVWDGNS 858

Query: 457 IAVSTLDGNITFFEPSTCEQTGSVEGRS 484
           +   +  G +  ++    + +  ++G +
Sbjct: 859 VLSGSQSGELLVWDLLGAKISERIQGHT 886



 Score = 35.9 bits (79), Expect = 0.52
 Identities = 15/48 (31%), Positives = 27/48 (56%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
           G+LLVW+    +   + QGH+  +TC+  +     ++TGG D ++  W
Sbjct: 866 GELLVWDLLGAKISERIQGHTGAVTCIWMNEQCSSIITGGEDRQIIFW 913



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 37/179 (20%), Positives = 73/179 (40%), Gaps = 10/179 (5%)

Query: 213 EMPDVNLIH--TLSISEHRISSISVS-PPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGH 269
           EMP     H   L+  EH +S  ++S      +  +    G + +W+  +   + +   H
Sbjct: 745 EMPGTKRHHFDLLAELEHDVSVDTISLNAASTLLVSGTKEGTVNIWDLTTATLMHQIPCH 804

Query: 270 SLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSA-NKKFFV 328
           S  +   A+SPD  HV++ G DG + V +   G    +    +      TC   +    +
Sbjct: 805 SGIVCDTAFSPDSRHVLSTGTDGCLNVIDVQTGMLISSMTSDEPQ----TCFVWDGNSVL 860

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKF 387
           S S  G +  +DL   +    +   +    +C+ ++        GG+D  +I  W +++
Sbjct: 861 SGSQSGELLVWDLLGAKISERIQGHT-GAVTCIWMNEQCSSIITGGED-RQIIFWKLQY 917



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 26/127 (20%), Positives = 52/127 (40%), Gaps = 5/127 (3%)

Query: 172 RHYIGDAIRNADRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRIS 231
           RH+  D +   +  V +  +  +  + LLV+G   G   + ++    L+H +      + 
Sbjct: 751 RHHF-DLLAELEHDVSVDTISLNAASTLLVSGTKEGTVNIWDLTTATLMHQIPCHSGIVC 809

Query: 232 SISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFD 291
             + SP    +  +    G L V + Q+   +          TC  +  DG  V++G   
Sbjct: 810 DTAFSPDSRHV-LSTGTDGCLNVIDVQTGMLISSMTSDE-PQTCFVW--DGNSVLSGSQS 865

Query: 292 GKVKVWN 298
           G++ VW+
Sbjct: 866 GELLVWD 872


>BC041124-1|AAH41124.1|  917|Homo sapiens neutral sphingomyelinase
           (N-SMase) activation associated factor protein.
          Length = 917

 Score = 62.1 bits (144), Expect = 7e-09
 Identities = 37/145 (25%), Positives = 67/145 (46%), Gaps = 7/145 (4%)

Query: 291 DGKVKVWNTTNGFCFVTFHE-HKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRT 349
           + K   WN          ++ HK  V+G+T S N     ++S D T++ +        R+
Sbjct: 608 ESKTLAWNNITKLQLHEHYKIHKEAVTGITVSRNGSSVFTTSQDSTLKMFSKESKMLQRS 667

Query: 350 LTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPT 409
           ++  ++   SC+ L        +   +   ++ +SI FG+  + L GH+  VS + +   
Sbjct: 668 ISFSNMALSSCLLLPGDATVITSSWDN--NVYFYSIAFGRRQDTLMGHDDAVSKICWH-- 723

Query: 410 LTSTRLASASWDGTVRLWDCIDREV 434
               RL SASWD TV++W  +  E+
Sbjct: 724 --DNRLYSASWDSTVKVWSGVPAEM 746



 Score = 39.5 bits (88), Expect = 0.043
 Identities = 29/136 (21%), Positives = 55/136 (40%), Gaps = 5/136 (3%)

Query: 269 HSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFV 328
           H + +  ++ +     +V+G  +G V +W+ T          H   V     S + +  +
Sbjct: 762 HDVSVDTISLNAASTLLVSGTKEGTVNIWDLTTATLMHQIPCHSGIVCDTAFSPDSRHVL 821

Query: 329 SSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG 388
           S+  DG +   D+       ++TS    +  C   D  G    +G Q   E+ VW +   
Sbjct: 822 STGTDGCLNVIDVQTGMLISSMTSDEPQR--CFVWD--GNSVLSGSQS-GELLVWDLLGA 876

Query: 389 KLLEVLGGHEAPVSSL 404
           K+ E + GH   V+ +
Sbjct: 877 KISERIQGHTGAVTCI 892



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 52/268 (19%), Positives = 105/268 (39%), Gaps = 17/268 (6%)

Query: 225 ISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLH 284
           I +  ++ I+VS  G  + F       L ++  +S+         ++ ++     P    
Sbjct: 628 IHKEAVTGITVSRNGSSV-FTTSQDSTLKMFSKESKMLQRSISFSNMALSSCLLLPGDAT 686

Query: 285 VVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL--- 341
           V+T  +D  V  ++   G    T   H   VS +    N+ +  S+S D TV+ +     
Sbjct: 687 VITSSWDNNVYFYSIAFGRRQDTLMGHDDAVSKICWHDNRLY--SASWDSTVKVWSGVPA 744

Query: 342 ----TRYRNFRTLTSPSL-VQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGG 396
               T+  +F  L      V    ++L+++     +G ++   + +W +    L+  +  
Sbjct: 745 EMPGTKRHHFDLLAELEHDVSVDTISLNAASTLLVSGTKEG-TVNIWDLTTATLMHQIPC 803

Query: 397 HEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEE 456
           H   V   AFSP   S  + S   DG + +   ID +       + SD  Q  F  DG  
Sbjct: 804 HSGIVCDTAFSP--DSRHVLSTGTDGCLNV---IDVQTGMLISSMTSDEPQRCFVWDGNS 858

Query: 457 IAVSTLDGNITFFEPSTCEQTGSVEGRS 484
           +   +  G +  ++    + +  ++G +
Sbjct: 859 VLSGSQSGELLVWDLLGAKISERIQGHT 886



 Score = 35.9 bits (79), Expect = 0.52
 Identities = 15/48 (31%), Positives = 27/48 (56%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVW 297
           G+LLVW+    +   + QGH+  +TC+  +     ++TGG D ++  W
Sbjct: 866 GELLVWDLLGAKISERIQGHTGAVTCIWMNEQCSSIITGGEDRQIIFW 913


>U63810-1|AAC24948.1|  339|Homo sapiens WD40 protein Ciao 1 protein.
          Length = 339

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 11/200 (5%)

Query: 236 SPPGDWIAFACPNIGQLLVWEWQSEQYVMKQ---QGHSLDMTCLAYSPDGLHVVTGGFDG 292
           +P G  +A +C    ++ +W  + + ++ K    +GH   +  +A+SP G ++ +  FD 
Sbjct: 25  NPAGTLLA-SCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83

Query: 293 KVKVW--NTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL---TRYRNF 347
              +W  N  +  C  T   H+  V  V  + +     + S D +V  +++     Y   
Sbjct: 84  TTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECV 143

Query: 348 RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFS 407
             L S +      V   S     +A   D  +++            L GHE+ V SLAF 
Sbjct: 144 SVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFD 203

Query: 408 PTLTSTRLASASWDGTVRLW 427
           P  +  RLAS S D TVR+W
Sbjct: 204 P--SGQRLASCSDDRTVRIW 221



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 14/201 (6%)

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNT--TNGFCFVTFHE-HKATVSGVTCSANKKFFVSSSL 332
           LA++P G  + + G D ++++W T   +  C     E H+ TV  V  S    +  S+S 
Sbjct: 22  LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81

Query: 333 DGTVRCYDLTRYRNFRTLTS--PSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG-- 388
           D T  C       +F  +T+      +   VA   SG   A   +D   ++VW +     
Sbjct: 82  DATT-CIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDK-SVWVWEVDEEDE 139

Query: 389 -KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW-DCIDREVQCEPIR-LNSDA 445
            + + VL  H   V  + + P  +   LASAS+D TV+L+ +  D  V C  +    S  
Sbjct: 140 YECVSVLNSHTQDVKHVVWHP--SQELLASASYDDTVKLYREEEDDWVCCATLEGHESTV 197

Query: 446 LQVAFRPDGEEIAVSTLDGNI 466
             +AF P G+ +A  + D  +
Sbjct: 198 WSLAFDPSGQRLASCSDDRTV 218



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           WS C   LA  S D TT I      +   + +L GH +++  V +      L T SR+  
Sbjct: 69  WSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKS 128

Query: 92  LCLWEASIDADE---LAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEKEYDSD 144
           + +WE   + DE   ++V    T   K V       L       D ++  +E + D
Sbjct: 129 VWVWEVD-EEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDD 183



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 20/88 (22%), Positives = 36/88 (40%)

Query: 19  VFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFER 78
           V      +V  + W     LLA  S D T K++  E  + +   +L GH   +  + F+ 
Sbjct: 145 VLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDP 204

Query: 79  KSLDLITVSRNGQLCLWEASIDADELAV 106
               L + S +  + +W   +  +E  V
Sbjct: 205 SGQRLASCSDDRTVRIWRQYLPGNEQGV 232


>EF011618-1|ABK41108.1|  339|Homo sapiens CDW8/WDR39 protein.
          Length = 339

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 11/200 (5%)

Query: 236 SPPGDWIAFACPNIGQLLVWEWQSEQYVMKQ---QGHSLDMTCLAYSPDGLHVVTGGFDG 292
           +P G  +A +C    ++ +W  + + ++ K    +GH   +  +A+SP G ++ +  FD 
Sbjct: 25  NPAGTLLA-SCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83

Query: 293 KVKVW--NTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL---TRYRNF 347
              +W  N  +  C  T   H+  V  V  + +     + S D +V  +++     Y   
Sbjct: 84  TTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECV 143

Query: 348 RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFS 407
             L S +      V   S     +A   D  +++            L GHE+ V SLAF 
Sbjct: 144 SVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFD 203

Query: 408 PTLTSTRLASASWDGTVRLW 427
           P  +  RLAS S D TVR+W
Sbjct: 204 P--SGQRLASCSDDRTVRIW 221



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 14/201 (6%)

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNT--TNGFCFVTFHE-HKATVSGVTCSANKKFFVSSSL 332
           LA++P G  + + G D ++++W T   +  C     E H+ TV  V  S    +  S+S 
Sbjct: 22  LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81

Query: 333 DGTVRCYDLTRYRNFRTLTS--PSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG-- 388
           D T  C       +F  +T+      +   VA   SG   A   +D   ++VW +     
Sbjct: 82  DATT-CIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDK-SVWVWEVDEEDE 139

Query: 389 -KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW-DCIDREVQCEPIR-LNSDA 445
            + + VL  H   V  + + P  +   LASAS+D TV+L+ +  D  V C  +    S  
Sbjct: 140 YECVSVLNSHTQDVKHVVWHP--SQELLASASYDDTVKLYREEEDDWVCCATLEGHESTV 197

Query: 446 LQVAFRPDGEEIAVSTLDGNI 466
             +AF P G+ +A  + D  +
Sbjct: 198 WSLAFDPSGQRLASCSDDRTV 218



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           WS C   LA  S D TT I      +   + +L GH +++  V +      L T SR+  
Sbjct: 69  WSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKS 128

Query: 92  LCLWEASIDADE---LAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEKEYDSD 144
           + +WE   + DE   ++V    T   K V       L       D ++  +E + D
Sbjct: 129 VWVWEVD-EEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDD 183



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 20/88 (22%), Positives = 36/88 (40%)

Query: 19  VFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFER 78
           V      +V  + W     LLA  S D T K++  E  + +   +L GH   +  + F+ 
Sbjct: 145 VLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDP 204

Query: 79  KSLDLITVSRNGQLCLWEASIDADELAV 106
               L + S +  + +W   +  +E  V
Sbjct: 205 SGQRLASCSDDRTVRIWRQYLPGNEQGV 232


>CR456802-1|CAG33083.1|  339|Homo sapiens CIAO1 protein.
          Length = 339

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 11/200 (5%)

Query: 236 SPPGDWIAFACPNIGQLLVWEWQSEQYVMKQ---QGHSLDMTCLAYSPDGLHVVTGGFDG 292
           +P G  +A +C    ++ +W  + + ++ K    +GH   +  +A+SP G ++ +  FD 
Sbjct: 25  NPAGTLLA-SCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83

Query: 293 KVKVW--NTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL---TRYRNF 347
              +W  N  +  C  T   H+  V  V  + +     + S D +V  +++     Y   
Sbjct: 84  TTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECV 143

Query: 348 RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFS 407
             L S +      V   S     +A   D  +++            L GHE+ V SLAF 
Sbjct: 144 SVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFD 203

Query: 408 PTLTSTRLASASWDGTVRLW 427
           P  +  RLAS S D TVR+W
Sbjct: 204 P--SGQRLASCSDDRTVRIW 221



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 14/201 (6%)

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNT--TNGFCFVTFHE-HKATVSGVTCSANKKFFVSSSL 332
           LA++P G  + + G D ++++W T   +  C     E H+ TV  V  S    +  S+S 
Sbjct: 22  LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81

Query: 333 DGTVRCYDLTRYRNFRTLTS--PSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG-- 388
           D T  C       +F  +T+      +   VA   SG   A   +D   ++VW +     
Sbjct: 82  DATT-CIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDK-SVWVWEVDEEDE 139

Query: 389 -KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW-DCIDREVQCEPIR-LNSDA 445
            + + VL  H   V  + + P  +   LASAS+D TV+L+ +  D  V C  +    S  
Sbjct: 140 YECVSVLNSHTQDVKHVVWHP--SQELLASASYDDTVKLYREEEDDWVCCATLEGHESTV 197

Query: 446 LQVAFRPDGEEIAVSTLDGNI 466
             +AF P G+ +A  + D  +
Sbjct: 198 WSLAFDPSGQRLASCSDDRTV 218



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           WS C   LA  S D TT I      +   + +L GH +++  V +      L T SR+  
Sbjct: 69  WSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKS 128

Query: 92  LCLWEASIDADE---LAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEKEYDSD 144
           + +WE   + DE   ++V    T   K V       L       D ++  +E + D
Sbjct: 129 VWVWEVD-EEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDD 183



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 20/88 (22%), Positives = 36/88 (40%)

Query: 19  VFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFER 78
           V      +V  + W     LLA  S D T K++  E  + +   +L GH   +  + F+ 
Sbjct: 145 VLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDP 204

Query: 79  KSLDLITVSRNGQLCLWEASIDADELAV 106
               L + S +  + +W   +  +E  V
Sbjct: 205 SGQRLASCSDDRTVRIWRQYLPGNEQGV 232


>BC032812-1|AAH32812.1|  339|Homo sapiens cytosolic iron-sulfur
           protein assembly 1 homolog (S. cerevisiae) protein.
          Length = 339

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 11/200 (5%)

Query: 236 SPPGDWIAFACPNIGQLLVWEWQSEQYVMKQ---QGHSLDMTCLAYSPDGLHVVTGGFDG 292
           +P G  +A +C    ++ +W  + + ++ K    +GH   +  +A+SP G ++ +  FD 
Sbjct: 25  NPAGTLLA-SCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83

Query: 293 KVKVW--NTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL---TRYRNF 347
              +W  N  +  C  T   H+  V  V  + +     + S D +V  +++     Y   
Sbjct: 84  TTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECV 143

Query: 348 RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFS 407
             L S +      V   S     +A   D  +++            L GHE+ V SLAF 
Sbjct: 144 SVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFD 203

Query: 408 PTLTSTRLASASWDGTVRLW 427
           P  +  RLAS S D TVR+W
Sbjct: 204 P--SGQRLASCSDDRTVRIW 221



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 14/201 (6%)

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNT--TNGFCFVTFHE-HKATVSGVTCSANKKFFVSSSL 332
           LA++P G  + + G D ++++W T   +  C     E H+ TV  V  S    +  S+S 
Sbjct: 22  LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81

Query: 333 DGTVRCYDLTRYRNFRTLTS--PSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG-- 388
           D T  C       +F  +T+      +   VA   SG   A   +D   ++VW +     
Sbjct: 82  DATT-CIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDK-SVWVWEVDEEDE 139

Query: 389 -KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW-DCIDREVQCEPIR-LNSDA 445
            + + VL  H   V  + + P  +   LASAS+D TV+L+ +  D  V C  +    S  
Sbjct: 140 YECVSVLNSHTQDVKHVVWHP--SQELLASASYDDTVKLYREEEDDWVCCATLEGHESTV 197

Query: 446 LQVAFRPDGEEIAVSTLDGNI 466
             +AF P G+ +A  + D  +
Sbjct: 198 WSLAFDPSGQRLASCSDDRTV 218



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           WS C   LA  S D TT I      +   + +L GH +++  V +      L T SR+  
Sbjct: 69  WSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKS 128

Query: 92  LCLWEASIDADE---LAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEKEYDSD 144
           + +WE   + DE   ++V    T   K V       L       D ++  +E + D
Sbjct: 129 VWVWEVD-EEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDD 183



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 20/88 (22%), Positives = 36/88 (40%)

Query: 19  VFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFER 78
           V      +V  + W     LLA  S D T K++  E  + +   +L GH   +  + F+ 
Sbjct: 145 VLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDP 204

Query: 79  KSLDLITVSRNGQLCLWEASIDADELAV 106
               L + S +  + +W   +  +E  V
Sbjct: 205 SGQRLASCSDDRTVRIWRQYLPGNEQGV 232


>BC026353-1|AAH26353.1|  677|Homo sapiens WD repeat domain 48
           protein.
          Length = 677

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 48/178 (26%), Positives = 79/178 (44%), Gaps = 11/178 (6%)

Query: 258 QSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSG 317
           + + Y+   + H+  +  +    +G  +++   D  VKVWN   GFC  T   HK  V  
Sbjct: 63  KQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKA 122

Query: 318 VTCSANKKFFVSSSLDGTVRCYD------LTRYRNFRTLTSPSLVQFS--CVALDSSGEF 369
           +  + +K+   S+ LD  +  +D      LT   N  T +S S  + S   +A++  G  
Sbjct: 123 LAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTI 182

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
             +G  +   + VW  +    L  L GH   V +L  +     T+  S S DGT+RLW
Sbjct: 183 IVSGSTEKV-LRVWDPRTCAKLMKLKGHTDNVKALLLN--RDGTQCLSGSSDGTIRLW 237



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 45/190 (23%), Positives = 83/190 (43%), Gaps = 15/190 (7%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWI-AFACPN 248
           A+ Y K+ +L+ +       FL    DVN +  L+ S + +++ S+S   D I + A   
Sbjct: 122 ALAYAKDKELVASAGLDRQIFLW---DVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQ 178

Query: 249 IGQLLV----------WEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN 298
           +G ++V          W+ ++   +MK +GH+ ++  L  + DG   ++G  DG +++W+
Sbjct: 179 LGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWS 238

Query: 299 TTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQF 358
                C  T+  H   V  +  +       S   D  + C DL R  + R L        
Sbjct: 239 LGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDL-RNPDIRVLICEEKAPV 297

Query: 359 SCVALDSSGE 368
             + LD S +
Sbjct: 298 LKMELDRSAD 307


>BC001395-1|AAH01395.1|  339|Homo sapiens cytosolic iron-sulfur
           protein assembly 1 homolog (S. cerevisiae) protein.
          Length = 339

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 11/200 (5%)

Query: 236 SPPGDWIAFACPNIGQLLVWEWQSEQYVMKQ---QGHSLDMTCLAYSPDGLHVVTGGFDG 292
           +P G  +A +C    ++ +W  + + ++ K    +GH   +  +A+SP G ++ +  FD 
Sbjct: 25  NPAGTLLA-SCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83

Query: 293 KVKVW--NTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL---TRYRNF 347
              +W  N  +  C  T   H+  V  V  + +     + S D +V  +++     Y   
Sbjct: 84  TTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECV 143

Query: 348 RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFS 407
             L S +      V   S     +A   D  +++            L GHE+ V SLAF 
Sbjct: 144 SVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFD 203

Query: 408 PTLTSTRLASASWDGTVRLW 427
           P  +  RLAS S D TVR+W
Sbjct: 204 P--SGQRLASCSDDRTVRIW 221



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 14/201 (6%)

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNT--TNGFCFVTFHE-HKATVSGVTCSANKKFFVSSSL 332
           LA++P G  + + G D ++++W T   +  C     E H+ TV  V  S    +  S+S 
Sbjct: 22  LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81

Query: 333 DGTVRCYDLTRYRNFRTLTS--PSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG-- 388
           D T  C       +F  +T+      +   VA   SG   A   +D   ++VW +     
Sbjct: 82  DATT-CIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDK-SVWVWEVDEEDE 139

Query: 389 -KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW-DCIDREVQCEPIR-LNSDA 445
            + + VL  H   V  + + P  +   LASAS+D TV+L+ +  D  V C  +    S  
Sbjct: 140 YECVSVLNSHTQDVKHVVWHP--SQELLASASYDDTVKLYREEEDDWVCCATLEGHESTV 197

Query: 446 LQVAFRPDGEEIAVSTLDGNI 466
             +AF P G+ +A  + D  +
Sbjct: 198 WSLAFDPSGQRLASCSDDRTV 218



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           WS C   LA  S D TT I      +   + +L GH +++  V +      L T SR+  
Sbjct: 69  WSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKS 128

Query: 92  LCLWEASIDADE---LAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEKEYDSD 144
           + +WE   + DE   ++V    T   K V       L       D ++  +E + D
Sbjct: 129 VWVWEVD-EEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDD 183



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 20/88 (22%), Positives = 36/88 (40%)

Query: 19  VFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFER 78
           V      +V  + W     LLA  S D T K++  E  + +   +L GH   +  + F+ 
Sbjct: 145 VLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDP 204

Query: 79  KSLDLITVSRNGQLCLWEASIDADELAV 106
               L + S +  + +W   +  +E  V
Sbjct: 205 SGQRLASCSDDRTVRIWRQYLPGNEQGV 232


>AK223257-1|BAD96977.1|  339|Homo sapiens WD40 protein Ciao1 variant
           protein.
          Length = 339

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 11/200 (5%)

Query: 236 SPPGDWIAFACPNIGQLLVWEWQSEQYVMKQ---QGHSLDMTCLAYSPDGLHVVTGGFDG 292
           +P G  +A +C    ++ +W  + + ++ K    +GH   +  +A+SP G ++ +  FD 
Sbjct: 25  NPAGTLLA-SCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83

Query: 293 KVKVW--NTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL---TRYRNF 347
              +W  N  +  C  T   H+  V  V  + +     + S D +V  +++     Y   
Sbjct: 84  TTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECV 143

Query: 348 RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFS 407
             L S +      V   S     +A   D  +++            L GHE+ V SLAF 
Sbjct: 144 SVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFD 203

Query: 408 PTLTSTRLASASWDGTVRLW 427
           P  +  RLAS S D TVR+W
Sbjct: 204 P--SGQRLASCSDDRTVRIW 221



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 14/201 (6%)

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNT--TNGFCFVTFHE-HKATVSGVTCSANKKFFVSSSL 332
           LA++P G  + + G D ++++W T   +  C     E H+ TV  V  S    +  S+S 
Sbjct: 22  LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81

Query: 333 DGTVRCYDLTRYRNFRTLTS--PSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG-- 388
           D T  C       +F  +T+      +   VA   SG   A   +D   ++VW +     
Sbjct: 82  DATT-CIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDK-SVWVWEVDEEDE 139

Query: 389 -KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW-DCIDREVQCEPIR-LNSDA 445
            + + VL  H   V  + + P  +   LASAS+D TV+L+ +  D  V C  +    S  
Sbjct: 140 YECVSVLNSHTQDVKHVVWHP--SQELLASASYDDTVKLYREEEDDWVCCATLEGHESTV 197

Query: 446 LQVAFRPDGEEIAVSTLDGNI 466
             +AF P G+ +A  + D  +
Sbjct: 198 WSLAFDPSGQRLASCSDDRTV 218



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           WS C   LA  S D TT I      +   + +L GH +++  V +      L T SR+  
Sbjct: 69  WSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKS 128

Query: 92  LCLWEASIDADE---LAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEKEYDSD 144
           + +WE   + DE   ++V    T   K V       L       D ++  +E + D
Sbjct: 129 VWVWEVD-EEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDD 183



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 20/88 (22%), Positives = 36/88 (40%)

Query: 19  VFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFER 78
           V      +V  + W     LLA  S D T K++  E  + +   +L GH   +  + F+ 
Sbjct: 145 VLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDP 204

Query: 79  KSLDLITVSRNGQLCLWEASIDADELAV 106
               L + S +  + +W   +  +E  V
Sbjct: 205 SGQRLASCSDDRTVRIWRQYLPGNEQGV 232


>AF492460-1|AAN64030.1| 1322|Homo sapiens WD repeat 17 protein.
          Length = 1322

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 32/116 (27%), Positives = 64/116 (55%), Gaps = 2/116 (1%)

Query: 229 RISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHV-VT 287
           ++  +  SP  + I  +  + G + +W++  +  +    GH+  +  L ++ +  ++ ++
Sbjct: 568 KVFHVKWSPLREGILCSGSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYLLIS 627

Query: 288 GGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSS-SLDGTVRCYDLT 342
           G +D  +KVW+T  G C  T ++H A V G+TC  ++ F ++S S D TVR + LT
Sbjct: 628 GSWDYTIKVWDTREGTCVDTVYDHGADVYGLTCHPSRPFTMASCSRDSTVRLWSLT 683



 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 52/187 (27%), Positives = 84/187 (44%), Gaps = 15/187 (8%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGK-VKVWNTTNGFCFVTF 308
           G + VW+  +   V    G+   +  L+++P GL+ + GG       +WN   G     F
Sbjct: 416 GTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAFIWNVQKGKIIQRF 475

Query: 309 HEHKATVSGVTCSA----NKKFFVSSSLDG--TVRCYDLTRYRNFRTLTSPSLVQFSCVA 362
           +EH    +G+ C A    + K   + S DG   +R  D      ++    P+ V F C  
Sbjct: 476 NEHGT--NGIFCIAWSHKDSKRIATCSSDGFCIIRTIDGKVLHKYK---HPAAV-FGCDW 529

Query: 363 LDSSGEFCAAGGQDV-FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
             ++ +  A G +D    ++  +    + L+V  GH A V  + +SP L    L S S D
Sbjct: 530 SQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSP-LREGILCSGSDD 588

Query: 422 GTVRLWD 428
           GTVR+WD
Sbjct: 589 GTVRIWD 595



 Score = 59.3 bits (137), Expect = 5e-08
 Identities = 62/243 (25%), Positives = 102/243 (41%), Gaps = 11/243 (4%)

Query: 199 LLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPG-DWIAFACPNIGQLLVWEW 257
           LL T    G   + ++  +  ++T   +E  I S+S +P G + IA      G   +W  
Sbjct: 408 LLATASFDGTIKVWDINTLTAVYTSPGNEGVIYSLSWAPGGLNCIAGGTSRNGAF-IWNV 466

Query: 258 QSEQYVMKQQGHSLD-MTCLAYS-PDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATV 315
           Q  + + +   H  + + C+A+S  D   + T   DG   +  T +G     + +H A V
Sbjct: 467 QKGKIIQRFNEHGTNGIFCIAWSHKDSKRIATCSSDGFCII-RTIDGKVLHKY-KHPAAV 524

Query: 316 SGVTCSANKKFFVSSSLDGT-VRCYDL-TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAG 373
            G   S N K  +++  + T VR Y + T       + S    +   V      E     
Sbjct: 525 FGCDWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCS 584

Query: 374 GQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDRE 433
           G D   + +W       + +L GH APV  L ++  +    L S SWD T+++WD   RE
Sbjct: 585 GSDDGTVRIWDYTQDACINILNGHTAPVRGLMWNTEIPYL-LISGSWDYTIKVWD--TRE 641

Query: 434 VQC 436
             C
Sbjct: 642 GTC 644



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 43/146 (29%), Positives = 62/146 (42%), Gaps = 5/146 (3%)

Query: 285 VVTGGFDGKVKVWN--TTNGFCFVTFHEHKATVSGVTCSANKK-FFVSSSLDGTVRCYDL 341
           + TG  D  V+V+   T++      F  H A V  V  S  ++    S S DGTVR +D 
Sbjct: 537 IATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGILCSGSDDGTVRIWDY 596

Query: 342 TRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPV 401
           T+      L   +      +          +G  D + I VW  + G  ++ +  H A V
Sbjct: 597 TQDACINILNGHTAPVRGLMWNTEIPYLLISGSWD-YTIKVWDTREGTCVDTVYDHGADV 655

Query: 402 SSLAFSPTLTSTRLASASWDGTVRLW 427
             L   P+   T +AS S D TVRLW
Sbjct: 656 YGLTCHPSRPFT-MASCSRDSTVRLW 680



 Score = 34.3 bits (75), Expect = 1.6
 Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 4/74 (5%)

Query: 31  DWSSCSR-LLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFE--RKSLDLITVS 87
           DWS  ++ ++A G +DT  +++ V    +  +   SGHT K+  V +   R+ + L + S
Sbjct: 528 DWSQNNKDMIATGCEDTNVRVYYVATSSDQPLKVFSGHTAKVFHVKWSPLREGI-LCSGS 586

Query: 88  RNGQLCLWEASIDA 101
            +G + +W+ + DA
Sbjct: 587 DDGTVRIWDYTQDA 600


>AF468833-1|AAL78650.1|  677|Homo sapiens WD repeat endosomal
           protein protein.
          Length = 677

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 48/178 (26%), Positives = 79/178 (44%), Gaps = 11/178 (6%)

Query: 258 QSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSG 317
           + + Y+   + H+  +  +    +G  +++   D  VKVWN   GFC  T   HK  V  
Sbjct: 63  KQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKA 122

Query: 318 VTCSANKKFFVSSSLDGTVRCYD------LTRYRNFRTLTSPSLVQFS--CVALDSSGEF 369
           +  + +K+   S+ LD  +  +D      LT   N  T +S S  + S   +A++  G  
Sbjct: 123 LAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTI 182

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
             +G  +   + VW  +    L  L GH   V +L  +     T+  S S DGT+RLW
Sbjct: 183 IVSGSTEKV-LRVWDPRTCAKLMKLKGHTDNVKALLLN--RDGTQCLSGSSDGTIRLW 237



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 45/190 (23%), Positives = 83/190 (43%), Gaps = 15/190 (7%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWI-AFACPN 248
           A+ Y K+ +L+ +       FL    DVN +  L+ S + +++ S+S   D I + A   
Sbjct: 122 ALAYAKDKELVASAGLDRQIFLW---DVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQ 178

Query: 249 IGQLLV----------WEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN 298
           +G ++V          W+ ++   +MK +GH+ ++  L  + DG   ++G  DG +++W+
Sbjct: 179 LGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWS 238

Query: 299 TTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQF 358
                C  T+  H   V  +  +       S   D  + C DL R  + R L        
Sbjct: 239 LGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDL-RNPDIRVLICEEKAPV 297

Query: 359 SCVALDSSGE 368
             + LD S +
Sbjct: 298 LKMELDRSAD 307


>AC004020-1|AAC23493.1|  339|Homo sapiens Unknown gene product
           protein.
          Length = 339

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 51/200 (25%), Positives = 86/200 (43%), Gaps = 11/200 (5%)

Query: 236 SPPGDWIAFACPNIGQLLVWEWQSEQYVMKQ---QGHSLDMTCLAYSPDGLHVVTGGFDG 292
           +P G  +A +C    ++ +W  + + ++ K    +GH   +  +A+SP G ++ +  FD 
Sbjct: 25  NPAGTLLA-SCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASFDA 83

Query: 293 KVKVW--NTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL---TRYRNF 347
              +W  N  +  C  T   H+  V  V  + +     + S D +V  +++     Y   
Sbjct: 84  TTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYECV 143

Query: 348 RTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFS 407
             L S +      V   S     +A   D  +++            L GHE+ V SLAF 
Sbjct: 144 SVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFD 203

Query: 408 PTLTSTRLASASWDGTVRLW 427
           P  +  RLAS S D TVR+W
Sbjct: 204 P--SGQRLASCSDDRTVRIW 221



 Score = 53.2 bits (122), Expect = 3e-06
 Identities = 54/201 (26%), Positives = 89/201 (44%), Gaps = 14/201 (6%)

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNT--TNGFCFVTFHE-HKATVSGVTCSANKKFFVSSSL 332
           LA++P G  + + G D ++++W T   +  C     E H+ TV  V  S    +  S+S 
Sbjct: 22  LAWNPAGTLLASCGGDRRIRIWGTEGDSWICKSVLSEGHQRTVRKVAWSPCGNYLASASF 81

Query: 333 DGTVRCYDLTRYRNFRTLTS--PSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFG-- 388
           D T  C       +F  +T+      +   VA   SG   A   +D   ++VW +     
Sbjct: 82  DATT-CIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDK-SVWVWEVDEEDE 139

Query: 389 -KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW-DCIDREVQCEPIR-LNSDA 445
            + + VL  H   V  + + P  +   LASAS+D TV+L+ +  D  V C  +    S  
Sbjct: 140 YECVSVLNSHTQDVKHVVWHP--SQELLASASYDDTVKLYREEEDDWVCCATLEGHESTV 197

Query: 446 LQVAFRPDGEEIAVSTLDGNI 466
             +AF P G+ +A  + D  +
Sbjct: 198 WSLAFDPSGQRLASCSDDRTV 218



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 30/116 (25%), Positives = 47/116 (40%), Gaps = 4/116 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           WS C   LA  S D TT I      +   + +L GH +++  V +      L T SR+  
Sbjct: 69  WSPCGNYLASASFDATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKS 128

Query: 92  LCLWEASIDADE---LAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEKEYDSD 144
           + +WE   + DE   ++V    T   K V       L       D ++  +E + D
Sbjct: 129 VWVWEVD-EEDEYECVSVLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDD 183



 Score = 32.7 bits (71), Expect = 4.9
 Identities = 20/88 (22%), Positives = 36/88 (40%)

Query: 19  VFKKALDEVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFER 78
           V      +V  + W     LLA  S D T K++  E  + +   +L GH   +  + F+ 
Sbjct: 145 VLNSHTQDVKHVVWHPSQELLASASYDDTVKLYREEEDDWVCCATLEGHESTVWSLAFDP 204

Query: 79  KSLDLITVSRNGQLCLWEASIDADELAV 106
               L + S +  + +W   +  +E  V
Sbjct: 205 SGQRLASCSDDRTVRIWRQYLPGNEQGV 232


>AB053276-1|BAB69430.1|  348|Homo sapiens TUWD12 protein.
          Length = 348

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 43/178 (24%), Positives = 77/178 (43%), Gaps = 4/178 (2%)

Query: 260 EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVT 319
           ++++     H+  + C  +SPDG  +V+   D  +K+W+TTN  C   F +     + V 
Sbjct: 4   QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVD 63

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFE 379
            + +     S+  D TV+ +D+ R               +C++   SG +      D   
Sbjct: 64  FNPSGTCIASAGSDQTVKVWDV-RVNKLLQHYQVHSGGVNCISFHPSGNYLITASSD-GT 121

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCE 437
           + +  +  G+L+  L GH  PV +++FS        AS   D  V LW     E+ C+
Sbjct: 122 LKILDLLEGRLIYTLQGHTGPVFTVSFSK--GGELFASGGADTQVLLWRTNFDELHCK 177



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 31/145 (21%), Positives = 63/145 (43%), Gaps = 1/145 (0%)

Query: 192 QYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ 251
           ++  + +L+V+        + +  +   ++  S S    + +  +P G  IA A  +   
Sbjct: 21  KFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSD-QT 79

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           + VW+ +  + +   Q HS  + C+++ P G +++T   DG +K+ +   G    T   H
Sbjct: 80  VKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGH 139

Query: 312 KATVSGVTCSANKKFFVSSSLDGTV 336
              V  V+ S   + F S   D  V
Sbjct: 140 TGPVFTVSFSKGGELFASGGADTQV 164



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 4/113 (3%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C+ +      L   S D T KI  ++ LE   +Y+L GHT  +  V F +      + 
Sbjct: 101 VNCISFHPSGNYLITASSDGTLKI--LDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 158

Query: 87  SRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEK 139
             + Q+ LW  +   DEL  K       KR+   +  +L + +       +EK
Sbjct: 159 GADTQVLLWRTNF--DELHCKGLTKRNLKRLHFDSPPHLLDIYPRTPHPHEEK 209



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 1/81 (1%)

Query: 219 LIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAY 278
           L+    +    ++ IS  P G+++  A  + G L + +    + +   QGH+  +  +++
Sbjct: 90  LLQHYQVHSGGVNCISFHPSGNYLITASSD-GTLKILDLLEGRLIYTLQGHTGPVFTVSF 148

Query: 279 SPDGLHVVTGGFDGKVKVWNT 299
           S  G    +GG D +V +W T
Sbjct: 149 SKGGELFASGGADTQVLLWRT 169


>AB053266-1|BAB69057.1|  348|Homo sapiens TUWD12 protein.
          Length = 348

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 43/178 (24%), Positives = 77/178 (43%), Gaps = 4/178 (2%)

Query: 260 EQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVT 319
           ++++     H+  + C  +SPDG  +V+   D  +K+W+TTN  C   F +     + V 
Sbjct: 4   QRFLYSLYRHTHWVRCAKFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVD 63

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFE 379
            + +     S+  D TV+ +D+ R               +C++   SG +      D   
Sbjct: 64  FNPSGTCIASAGSDQTVKVWDV-RVNKLLQHYQVHSGGVNCISFHPSGNYLITASSD-GT 121

Query: 380 IFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCE 437
           + +  +  G+L+  L GH  PV +++FS        AS   D  V LW     E+ C+
Sbjct: 122 LKILDLLEGRLIYTLQGHTGPVFTVSFSK--GGELFASGGADTQVLLWRTNFDELHCK 177



 Score = 48.8 bits (111), Expect = 7e-05
 Identities = 31/145 (21%), Positives = 63/145 (43%), Gaps = 1/145 (0%)

Query: 192 QYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQ 251
           ++  + +L+V+        + +  +   ++  S S    + +  +P G  IA A  +   
Sbjct: 21  KFSPDGRLIVSCSEDKTIKIWDTTNKQCVNNFSDSVGFANFVDFNPSGTCIASAGSD-QT 79

Query: 252 LLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEH 311
           + VW+ +  + +   Q HS  + C+++ P G +++T   DG +K+ +   G    T   H
Sbjct: 80  VKVWDVRVNKLLQHYQVHSGGVNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGH 139

Query: 312 KATVSGVTCSANKKFFVSSSLDGTV 336
              V  V+ S   + F S   D  V
Sbjct: 140 TGPVFTVSFSKGGELFASGGADTQV 164



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 29/113 (25%), Positives = 47/113 (41%), Gaps = 4/113 (3%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C+ +      L   S D T KI  ++ LE   +Y+L GHT  +  V F +      + 
Sbjct: 101 VNCISFHPSGNYLITASSDGTLKI--LDLLEGRLIYTLQGHTGPVFTVSFSKGGELFASG 158

Query: 87  SRNGQLCLWEASIDADELAVKQDDTSRKKRVRLQNEGNLEEEFDAKDDIEKEK 139
             + Q+ LW  +   DEL  K       KR+   +  +L + +       +EK
Sbjct: 159 GADTQVLLWRTNF--DELHCKGLTKRNLKRLHFDSPPHLLDIYPRTPHPHEEK 209



 Score = 33.5 bits (73), Expect = 2.8
 Identities = 19/81 (23%), Positives = 39/81 (48%), Gaps = 1/81 (1%)

Query: 219 LIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAY 278
           L+    +    ++ IS  P G+++  A  + G L + +    + +   QGH+  +  +++
Sbjct: 90  LLQHYQVHSGGVNCISFHPSGNYLITASSD-GTLKILDLLEGRLIYTLQGHTGPVFTVSF 148

Query: 279 SPDGLHVVTGGFDGKVKVWNT 299
           S  G    +GG D +V +W T
Sbjct: 149 SKGGELFASGGADTQVLLWRT 169


>AB040882-1|BAA95973.2|  680|Homo sapiens KIAA1449 protein protein.
          Length = 680

 Score = 61.7 bits (143), Expect = 9e-09
 Identities = 48/178 (26%), Positives = 79/178 (44%), Gaps = 11/178 (6%)

Query: 258 QSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSG 317
           + + Y+   + H+  +  +    +G  +++   D  VKVWN   GFC  T   HK  V  
Sbjct: 66  KQDPYIASMEHHTDWVNDIVLCCNGKTLISASSDTTVKVWNAHKGFCMSTLRTHKDYVKA 125

Query: 318 VTCSANKKFFVSSSLDGTVRCYD------LTRYRNFRTLTSPSLVQFS--CVALDSSGEF 369
           +  + +K+   S+ LD  +  +D      LT   N  T +S S  + S   +A++  G  
Sbjct: 126 LAYAKDKELVASAGLDRQIFLWDVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQLGTI 185

Query: 370 CAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
             +G  +   + VW  +    L  L GH   V +L  +     T+  S S DGT+RLW
Sbjct: 186 IVSGSTEKV-LRVWDPRTCAKLMKLKGHTDNVKALLLN--RDGTQCLSGSSDGTIRLW 240



 Score = 52.0 bits (119), Expect = 7e-06
 Identities = 45/190 (23%), Positives = 83/190 (43%), Gaps = 15/190 (7%)

Query: 190 AVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWI-AFACPN 248
           A+ Y K+ +L+ +       FL    DVN +  L+ S + +++ S+S   D I + A   
Sbjct: 125 ALAYAKDKELVASAGLDRQIFLW---DVNTLTALTASNNTVTTSSLSGNKDSIYSLAMNQ 181

Query: 249 IGQLLV----------WEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN 298
           +G ++V          W+ ++   +MK +GH+ ++  L  + DG   ++G  DG +++W+
Sbjct: 182 LGTIIVSGSTEKVLRVWDPRTCAKLMKLKGHTDNVKALLLNRDGTQCLSGSSDGTIRLWS 241

Query: 299 TTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQF 358
                C  T+  H   V  +  +       S   D  + C DL R  + R L        
Sbjct: 242 LGQQRCIATYRVHDEGVWALQVNDAFTHVYSGGRDRKIYCTDL-RNPDIRVLICEEKAPV 300

Query: 359 SCVALDSSGE 368
             + LD S +
Sbjct: 301 LKMELDRSAD 310


>EF011621-1|ABK41111.1|  357|Homo sapiens CDW11/WDR57 protein.
          Length = 357

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 38/166 (22%), Positives = 78/166 (46%), Gaps = 9/166 (5%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           G + +W+ + +  +   Q ++  +  + ++     +++GG D  +KVW+        T  
Sbjct: 174 GTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMR 232

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY---RNFRTLTSPSLVQFSCVALDSS 366
            H  +V+G++ S+   + +S+++D TVR +D+  +        +   ++  F    L  S
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCS 292

Query: 367 ----GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
               G   AAG  D F ++VW     ++L  L GH   ++ +AF P
Sbjct: 293 WSPDGSKIAAGSADRF-VYVWDTTSRRILYKLPGHAGSINEVAFHP 337



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 41/211 (19%), Positives = 87/211 (41%), Gaps = 9/211 (4%)

Query: 263 VMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC--FVTFHEHKATVSGVTC 320
           +M   GH  ++ C  + P+G  + + GFD  + +WN   G C  + T   H   V  +  
Sbjct: 59  IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWN-VYGDCDNYATLKGHSGAVMELHY 117

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           + +     S+S D TV  +D       + L   +    SC       +    G  D   +
Sbjct: 118 NTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDD-GTV 176

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+    ++     +     LA +   TS ++ S   D  +++WD    ++    +R
Sbjct: 177 KLWDIRKKAAIQTF---QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKL-TYTMR 232

Query: 441 LNSDALQ-VAFRPDGEEIAVSTLDGNITFFE 470
            ++D++  ++   +G  +  + +D  +  ++
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263



 Score = 40.3 bits (90), Expect = 0.024
 Identities = 34/164 (20%), Positives = 73/164 (44%), Gaps = 9/164 (5%)

Query: 178 AIRNADRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSP 237
           AI+      ++ AV ++  +  +++G       + ++    L +T+      ++ +S+S 
Sbjct: 186 AIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSS 245

Query: 238 PGDWIAFACPNIGQLLVWEWQ----SEQYVMKQQG--HSLDMTCL--AYSPDGLHVVTGG 289
            G ++     +   + VW+ +     E+ V   QG  H+ +   L  ++SPDG  +  G 
Sbjct: 246 EGSYLLSNAMD-NTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGS 304

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLD 333
            D  V VW+TT+         H  +++ V    ++   +S+S D
Sbjct: 305 ADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348


>BC001494-1|AAH01494.1|  357|Homo sapiens WD repeat domain 57 (U5
           snRNP specific) protein.
          Length = 357

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 38/166 (22%), Positives = 78/166 (46%), Gaps = 9/166 (5%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           G + +W+ + +  +   Q ++  +  + ++     +++GG D  +KVW+        T  
Sbjct: 174 GTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMR 232

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY---RNFRTLTSPSLVQFSCVALDSS 366
            H  +V+G++ S+   + +S+++D TVR +D+  +        +   ++  F    L  S
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCS 292

Query: 367 ----GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
               G   AAG  D F ++VW     ++L  L GH   ++ +AF P
Sbjct: 293 WSPDGSKIAAGSADRF-VYVWDTTSRRILYKLPGHAGSINEVAFHP 337



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 41/211 (19%), Positives = 87/211 (41%), Gaps = 9/211 (4%)

Query: 263 VMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC--FVTFHEHKATVSGVTC 320
           +M   GH  ++ C  + P+G  + + GFD  + +WN   G C  + T   H   V  +  
Sbjct: 59  IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWN-VYGDCDNYATLKGHSGAVMELHY 117

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           + +     S+S D TV  +D       + L   +    SC       +    G  D   +
Sbjct: 118 NTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDD-GTV 176

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+    ++     +     LA +   TS ++ S   D  +++WD    ++    +R
Sbjct: 177 KLWDIRKKAAIQTF---QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKL-TYTMR 232

Query: 441 LNSDALQ-VAFRPDGEEIAVSTLDGNITFFE 470
            ++D++  ++   +G  +  + +D  +  ++
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263



 Score = 40.3 bits (90), Expect = 0.024
 Identities = 34/164 (20%), Positives = 73/164 (44%), Gaps = 9/164 (5%)

Query: 178 AIRNADRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSP 237
           AI+      ++ AV ++  +  +++G       + ++    L +T+      ++ +S+S 
Sbjct: 186 AIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSS 245

Query: 238 PGDWIAFACPNIGQLLVWEWQ----SEQYVMKQQG--HSLDMTCL--AYSPDGLHVVTGG 289
            G ++     +   + VW+ +     E+ V   QG  H+ +   L  ++SPDG  +  G 
Sbjct: 246 EGSYLLSNAMD-NTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGS 304

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLD 333
            D  V VW+TT+         H  +++ V    ++   +S+S D
Sbjct: 305 ADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348


>AL451070-1|CAH71848.1|  357|Homo sapiens WD repeat domain 57 (U5
           snRNP specific) protein.
          Length = 357

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 38/166 (22%), Positives = 78/166 (46%), Gaps = 9/166 (5%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           G + +W+ + +  +   Q ++  +  + ++     +++GG D  +KVW+        T  
Sbjct: 174 GTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMR 232

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY---RNFRTLTSPSLVQFSCVALDSS 366
            H  +V+G++ S+   + +S+++D TVR +D+  +        +   ++  F    L  S
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCS 292

Query: 367 ----GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
               G   AAG  D F ++VW     ++L  L GH   ++ +AF P
Sbjct: 293 WSPDGSKIAAGSADRF-VYVWDTTSRRILYKLPGHAGSINEVAFHP 337



 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 41/211 (19%), Positives = 87/211 (41%), Gaps = 9/211 (4%)

Query: 263 VMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC--FVTFHEHKATVSGVTC 320
           +M   GH  ++ C  + P+G  + + GFD  + +WN   G C  + T   H   V  +  
Sbjct: 59  IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWN-VYGDCDNYATLKGHSGAVMELHY 117

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           + +     S+S D TV  +D       + L   +    SC       +    G  D   +
Sbjct: 118 NTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARRGPQLVCTGSDD-GTV 176

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+    ++     +     LA +   TS ++ S   D  +++WD    ++    +R
Sbjct: 177 KLWDIRKKAAIQTF---QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKL-TYTMR 232

Query: 441 LNSDALQ-VAFRPDGEEIAVSTLDGNITFFE 470
            ++D++  ++   +G  +  + +D  +  ++
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263



 Score = 40.3 bits (90), Expect = 0.024
 Identities = 34/164 (20%), Positives = 73/164 (44%), Gaps = 9/164 (5%)

Query: 178 AIRNADRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSP 237
           AI+      ++ AV ++  +  +++G       + ++    L +T+      ++ +S+S 
Sbjct: 186 AIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSS 245

Query: 238 PGDWIAFACPNIGQLLVWEWQ----SEQYVMKQQG--HSLDMTCL--AYSPDGLHVVTGG 289
            G ++     +   + VW+ +     E+ V   QG  H+ +   L  ++SPDG  +  G 
Sbjct: 246 EGSYLLSNAMD-NTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGS 304

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLD 333
            D  V VW+TT+         H  +++ V    ++   +S+S D
Sbjct: 305 ADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348


>AF490390-1|AAM97147.1|  631|Homo sapiens sperm-associated WD repeat
           protein protein.
          Length = 631

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 53/213 (24%), Positives = 81/213 (38%), Gaps = 5/213 (2%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTC 275
           D  L +   + E  +S +S+ P  D I  +C       V        ++   GH+  ++ 
Sbjct: 341 DYKLKNIFRLHELPVSCVSMQPHKD-ILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSD 399

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGT 335
             + P G  + T   D  VK+W+   G C +TF  H   V   T  +   F  SSSLD T
Sbjct: 400 CCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKT 459

Query: 336 VRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLG 395
            + +D+   R   TL   +    S      S     +       I  W  + G   + L 
Sbjct: 460 SKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSI--WDARTGICEQSLY 517

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           GH   ++   F P      +AS    G  +LWD
Sbjct: 518 GHMHSINDAIFDP--RGHMIASCDACGVTKLWD 548



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 42/176 (23%), Positives = 74/176 (42%), Gaps = 9/176 (5%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+  SE+      GH+  +  + + P    ++T   D  + +W+   G C  + + H  
Sbjct: 462 IWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMH 521

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTL-TSPSLVQFSCVALDSSGEFCA- 371
           +++            S    G  + +D  +     ++   PS    + V  DSSG   A 
Sbjct: 522 SINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPS--PGNEVNFDSSGRVLAQ 579

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           A G  V  I +  +K G++ +++ GHE    ++ FS       L S   DGTVR W
Sbjct: 580 ASGNGV--IHLLDLKSGEIHKLM-GHENEAHTVVFSH--DGEILFSGGSDGTVRTW 630



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           W SC   +A  S D T+KI  V         +L GHTD +  + F   S  L+T S +  
Sbjct: 444 WHSCGNFVASSSLDKTSKIWDVN--SERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKT 501

Query: 92  LCLWEA 97
           L +W+A
Sbjct: 502 LSIWDA 507


>AF310672-1|AAM63956.1|  631|Homo sapiens PF20 variant 1a protein.
          Length = 631

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 53/213 (24%), Positives = 81/213 (38%), Gaps = 5/213 (2%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTC 275
           D  L +   + E  +S +S+ P  D I  +C       V        ++   GH+  ++ 
Sbjct: 341 DYKLKNIFRLHELPVSCVSMQPHKD-ILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSD 399

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGT 335
             + P G  + T   D  VK+W+   G C +TF  H   V   T  +   F  SSSLD T
Sbjct: 400 CCFHPSGDKLATSSGDTTVKLWDLCTGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKT 459

Query: 336 VRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLG 395
            + +D+   R   TL   +    S      S     +       I  W  + G   + L 
Sbjct: 460 SKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSI--WDARTGICEQSLY 517

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           GH   ++   F P      +AS    G  +LWD
Sbjct: 518 GHMHSINDAIFDP--RGHMIASCDACGVTKLWD 548



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 42/176 (23%), Positives = 74/176 (42%), Gaps = 9/176 (5%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+  SE+      GH+  +  + + P    ++T   D  + +W+   G C  + + H  
Sbjct: 462 IWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMH 521

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTL-TSPSLVQFSCVALDSSGEFCA- 371
           +++            S    G  + +D  +     ++   PS    + V  DSSG   A 
Sbjct: 522 SINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPS--PGNEVNFDSSGRVLAQ 579

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           A G  V  I +  +K G++ +++ GHE    ++ FS       L S   DGTVR W
Sbjct: 580 ASGNGV--IHLLDLKSGEIHKLM-GHENEAHTVVFSH--DGEILFSGGSDGTVRTW 630



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           W SC   +A  S D T+KI  V         +L GHTD +  + F   S  L+T S +  
Sbjct: 444 WHSCGNFVASSSLDKTSKIWDVN--SERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKT 501

Query: 92  LCLWEA 97
           L +W+A
Sbjct: 502 LSIWDA 507


>AF090988-1|AAC69625.1|  357|Homo sapiens U5 snRNP-specific 40 kDa
           protein protein.
          Length = 357

 Score = 60.5 bits (140), Expect = 2e-08
 Identities = 38/166 (22%), Positives = 78/166 (46%), Gaps = 9/166 (5%)

Query: 250 GQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFH 309
           G + +W+ + +  +   Q ++  +  + ++     +++GG D  +KVW+        T  
Sbjct: 174 GTVKLWDIRKKAAIQTFQ-NTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMR 232

Query: 310 EHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRY---RNFRTLTSPSLVQFSCVALDSS 366
            H  +V+G++ S+   + +S+++D TVR +D+  +        +   ++  F    L  S
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCS 292

Query: 367 ----GEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSP 408
               G   AAG  D F ++VW     ++L  L GH   ++ +AF P
Sbjct: 293 WSPDGSKIAAGSADRF-VYVWDTTSRRILYKLPGHAGSINEVAFHP 337



 Score = 53.6 bits (123), Expect = 2e-06
 Identities = 42/211 (19%), Positives = 88/211 (41%), Gaps = 9/211 (4%)

Query: 263 VMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFC--FVTFHEHKATVSGVTC 320
           +M   GH  ++ C  + P+G  + + GFD  + +WN   G C  + T   H   V  +  
Sbjct: 59  IMLLSGHEGEVYCCKFHPNGSTLASAGFDRLILLWN-VYGDCDNYATLKGHSGAVMELHY 117

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
           + +     S+S D TV  +D       + L   +    SC     S +    G  D   +
Sbjct: 118 NTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPARKSPQLVCTGSDD-GTV 176

Query: 381 FVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIR 440
            +W I+    ++     +     LA +   TS ++ S   D  +++WD    ++    +R
Sbjct: 177 KLWDIRKKAAIQTF---QNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKL-TYTMR 232

Query: 441 LNSDALQ-VAFRPDGEEIAVSTLDGNITFFE 470
            ++D++  ++   +G  +  + +D  +  ++
Sbjct: 233 GHADSVTGLSLSSEGSYLLSNAMDNTVRVWD 263



 Score = 40.3 bits (90), Expect = 0.024
 Identities = 34/164 (20%), Positives = 73/164 (44%), Gaps = 9/164 (5%)

Query: 178 AIRNADRKVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSP 237
           AI+      ++ AV ++  +  +++G       + ++    L +T+      ++ +S+S 
Sbjct: 186 AIQTFQNTYQVLAVTFNDTSDQIISGGIDNDIKVWDLRQNKLTYTMRGHADSVTGLSLSS 245

Query: 238 PGDWIAFACPNIGQLLVWEWQ----SEQYVMKQQG--HSLDMTCL--AYSPDGLHVVTGG 289
            G ++     +   + VW+ +     E+ V   QG  H+ +   L  ++SPDG  +  G 
Sbjct: 246 EGSYLLSNAMD-NTVRVWDVRPFAPKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGS 304

Query: 290 FDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLD 333
            D  V VW+TT+         H  +++ V    ++   +S+S D
Sbjct: 305 ADRFVYVWDTTSRRILYKLPGHAGSINEVAFHPDEPIIISASSD 348


>BC111490-1|AAI11491.1|  768|Homo sapiens BRWD3 protein protein.
          Length = 768

 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 12/192 (6%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GHS +++ +A + +   +  G  D  V+VW             H A
Sbjct: 206 IWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSA 265

Query: 314 TVSGVT-CSANK---KFFVSSSLDGTVRCYDL-TRYRNFR------TLTSPSLVQFSCVA 362
           +++ +  C + K   ++  S+  DGT+  +    +   FR      T  S   VQ SC +
Sbjct: 266 SITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSS 325

Query: 363 LDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
             S G F   G  D V  I+    +  + +  L  H   V ++ F     S R  S S D
Sbjct: 326 FSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRD 385

Query: 422 GTVRLWDCIDRE 433
           GT R+W    +E
Sbjct: 386 GTARIWQYQQQE 397



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 6/124 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+A+   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQD-VFEIFV 382
            + S D  VR + L        L     S + +QF C +   +  +  + G D     + 
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF-CPSTKGTNRYLTSTGADGTICFWQ 296

Query: 383 WSIK 386
           W +K
Sbjct: 297 WHVK 300



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
           CVA D SG     G  D   + +W+   G+LL  L GH A +S +A +    +T +A+ S
Sbjct: 185 CVAFDRSGRRIFTGSDDCL-VKIWATDDGRLLATLRGHSAEISDMAVN--YENTLIAAGS 241

Query: 420 WDGTVRLW 427
            D  VR+W
Sbjct: 242 CDKVVRVW 249



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 49/225 (21%), Positives = 86/225 (38%), Gaps = 29/225 (12%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVW----NTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           + ++C ++S  G+ + TG  D  ++++            +  H  K        + +   
Sbjct: 319 VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLR 378

Query: 327 FVSSSLDGTVRC--YDLTRYRNF-----RTLTSPSL---------VQFSCVALDSSGEFC 370
           FVS S DGT R   Y    +++        +T  +L         ++ + VA D      
Sbjct: 379 FVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTV 438

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
                + F + VW+   G+LL  L GH+  V  L   P      + SA  DG + +WD +
Sbjct: 439 ITAVNN-FLLKVWNSITGQLLHTLSGHDDEVFVLEAHP-FDQRIILSAGHDGNIFIWD-L 495

Query: 431 DREVQCEPI------RLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
           DR  +          + +       F PDG   A +   G++  F
Sbjct: 496 DRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLF 540



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF--ERKSLDL 83
           +++C  +SS    +  GS D   +I+ +       +  L  HTDK++ V F     SL  
Sbjct: 320 QISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRF 379

Query: 84  ITVSRNGQLCLWE 96
           ++ SR+G   +W+
Sbjct: 380 VSGSRDGTARIWQ 392



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++ L  +       L+HTLS  +  +  +   P    I  
Sbjct: 423 KLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIIL 482

Query: 245 ACPNIGQLLVWE----WQSEQY--VMKQQGHSLDMTCLAYSPDGLH 284
           +  + G + +W+     +   Y  +++ QGH     C  +SPDG H
Sbjct: 483 SAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC-KFSPDGNH 527


>BC025379-1|AAH25379.1|  571|Homo sapiens SPAG16 protein protein.
          Length = 571

 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 53/213 (24%), Positives = 81/213 (38%), Gaps = 5/213 (2%)

Query: 216 DVNLIHTLSISEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTC 275
           D  L +   + E  +S +S+ P  D I  +C       V        ++   GH+  ++ 
Sbjct: 281 DYKLKNIFRLHELPVSCVSMHPHKD-ILVSCGEDRLWKVLGLPKCNVLLTGFGHTDWLSD 339

Query: 276 LAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGT 335
             + P G  + T   D  VK+W+   G C +TF  H   V   T  +   F  SSSLD T
Sbjct: 340 CCFHPSGDKLATSSGDTTVKLWDLCKGDCILTFEGHSRAVWSCTWHSCGNFVASSSLDKT 399

Query: 336 VRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLG 395
            + +D+   R   TL   +    S      S     +       I  W  + G   + L 
Sbjct: 400 SKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSI--WDARTGICEQSLY 457

Query: 396 GHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
           GH   ++   F P      +AS    G  +LWD
Sbjct: 458 GHMHSINDAIFDP--RGHMIASCDACGVTKLWD 488



 Score = 50.4 bits (115), Expect = 2e-05
 Identities = 42/176 (23%), Positives = 74/176 (42%), Gaps = 9/176 (5%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+  SE+      GH+  +  + + P    ++T   D  + +W+   G C  + + H  
Sbjct: 402 IWDVNSERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMH 461

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTL-TSPSLVQFSCVALDSSGEFCA- 371
           +++            S    G  + +D  +     ++   PS    + V  DSSG   A 
Sbjct: 462 SINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPS--PGNEVNFDSSGRVLAQ 519

Query: 372 AGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           A G  V  I +  +K G++ +++ GHE    ++ FS       L S   DGTVR W
Sbjct: 520 ASGNGV--IHLLDLKSGEIHKLM-GHENEAHTVVFSH--DGEILFSGGSDGTVRTW 570



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 23/66 (34%), Positives = 32/66 (48%), Gaps = 2/66 (3%)

Query: 32  WSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITVSRNGQ 91
           W SC   +A  S D T+KI  V         +L GHTD +  + F   S  L+T S +  
Sbjct: 384 WHSCGNFVASSSLDKTSKIWDVN--SERCRCTLYGHTDSVNSIEFFPFSNTLLTSSADKT 441

Query: 92  LCLWEA 97
           L +W+A
Sbjct: 442 LSIWDA 447


>AY497047-1|AAS45472.1| 1631|Homo sapiens bromodomain and WD repeat
           domain containing 3 variant BRWD3-B protein.
          Length = 1631

 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 12/192 (6%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GHS +++ +A + +   +  G  D  V+VW             H A
Sbjct: 35  IWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSA 94

Query: 314 TVSGVT-CSANK---KFFVSSSLDGTVRCYDL-TRYRNFR------TLTSPSLVQFSCVA 362
           +++ +  C + K   ++  S+  DGT+  +    +   FR      T  S   VQ SC +
Sbjct: 95  SITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSS 154

Query: 363 LDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
             S G F   G  D V  I+    +  + +  L  H   V ++ F     S R  S S D
Sbjct: 155 FSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRD 214

Query: 422 GTVRLWDCIDRE 433
           GT R+W    +E
Sbjct: 215 GTARIWQYQQQE 226



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 6/124 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+A+   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 7   GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 66

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQD-VFEIFV 382
            + S D  VR + L        L     S + +QF C +   +  +  + G D     + 
Sbjct: 67  AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF-CPSTKGTNRYLTSTGADGTICFWQ 125

Query: 383 WSIK 386
           W +K
Sbjct: 126 WHVK 129



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
           CVA D SG     G  D   + +W+   G+LL  L GH A +S +A +    +T +A+ S
Sbjct: 14  CVAFDRSGRRIFTGSDDCL-VKIWATDDGRLLATLRGHSAEISDMAVN--YENTLIAAGS 70

Query: 420 WDGTVRLW 427
            D  VR+W
Sbjct: 71  CDKVVRVW 78



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 49/225 (21%), Positives = 86/225 (38%), Gaps = 29/225 (12%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVW----NTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           + ++C ++S  G+ + TG  D  ++++            +  H  K        + +   
Sbjct: 148 VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLR 207

Query: 327 FVSSSLDGTVRC--YDLTRYRNF-----RTLTSPSL---------VQFSCVALDSSGEFC 370
           FVS S DGT R   Y    +++        +T  +L         ++ + VA D      
Sbjct: 208 FVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTV 267

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
                + F + VW+   G+LL  L GH+  V  L   P      + SA  DG + +WD +
Sbjct: 268 ITAVNN-FLLKVWNSITGQLLHTLSGHDDEVFVLEAHP-FDQRIILSAGHDGNIFIWD-L 324

Query: 431 DREVQCEPI------RLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
           DR  +          + +       F PDG   A +   G++  F
Sbjct: 325 DRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLF 369



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF--ERKSLDL 83
           +++C  +SS    +  GS D   +I+ +       +  L  HTDK++ V F     SL  
Sbjct: 149 QISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRF 208

Query: 84  ITVSRNGQLCLWE 96
           ++ SR+G   +W+
Sbjct: 209 VSGSRDGTARIWQ 221



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++ L  +       L+HTLS  +  +  +   P    I  
Sbjct: 252 KLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIIL 311

Query: 245 ACPNIGQLLVWE----WQSEQY--VMKQQGHSLDMTCLAYSPDGLH 284
           +  + G + +W+     +   Y  +++ QGH     C  +SPDG H
Sbjct: 312 SAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC-KFSPDGNH 356


>AY497046-1|AAS45471.1| 1802|Homo sapiens bromodomain and WD repeat
           domain containing 3 variant BRWD3-A protein.
          Length = 1802

 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 12/192 (6%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GHS +++ +A + +   +  G  D  V+VW             H A
Sbjct: 206 IWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSA 265

Query: 314 TVSGVT-CSANK---KFFVSSSLDGTVRCYDL-TRYRNFR------TLTSPSLVQFSCVA 362
           +++ +  C + K   ++  S+  DGT+  +    +   FR      T  S   VQ SC +
Sbjct: 266 SITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSS 325

Query: 363 LDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
             S G F   G  D V  I+    +  + +  L  H   V ++ F     S R  S S D
Sbjct: 326 FSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRD 385

Query: 422 GTVRLWDCIDRE 433
           GT R+W    +E
Sbjct: 386 GTARIWQYQQQE 397



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 6/124 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+A+   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQD-VFEIFV 382
            + S D  VR + L        L     S + +QF C +   +  +  + G D     + 
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF-CPSTKGTNRYLTSTGADGTICFWQ 296

Query: 383 WSIK 386
           W +K
Sbjct: 297 WHVK 300



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
           CVA D SG     G  D   + +W+   G+LL  L GH A +S +A +    +T +A+ S
Sbjct: 185 CVAFDRSGRRIFTGSDDCL-VKIWATDDGRLLATLRGHSAEISDMAVN--YENTLIAAGS 241

Query: 420 WDGTVRLW 427
            D  VR+W
Sbjct: 242 CDKVVRVW 249



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 49/225 (21%), Positives = 86/225 (38%), Gaps = 29/225 (12%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVW----NTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           + ++C ++S  G+ + TG  D  ++++            +  H  K        + +   
Sbjct: 319 VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLR 378

Query: 327 FVSSSLDGTVRC--YDLTRYRNF-----RTLTSPSL---------VQFSCVALDSSGEFC 370
           FVS S DGT R   Y    +++        +T  +L         ++ + VA D      
Sbjct: 379 FVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTV 438

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
                + F + VW+   G+LL  L GH+  V  L   P      + SA  DG + +WD +
Sbjct: 439 ITAVNN-FLLKVWNSITGQLLHTLSGHDDEVFVLEAHP-FDQRIILSAGHDGNIFIWD-L 495

Query: 431 DREVQCEPI------RLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
           DR  +          + +       F PDG   A +   G++  F
Sbjct: 496 DRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLF 540



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF--ERKSLDL 83
           +++C  +SS    +  GS D   +I+ +       +  L  HTDK++ V F     SL  
Sbjct: 320 QISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRF 379

Query: 84  ITVSRNGQLCLWE 96
           ++ SR+G   +W+
Sbjct: 380 VSGSRDGTARIWQ 392



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++ L  +       L+HTLS  +  +  +   P    I  
Sbjct: 423 KLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIIL 482

Query: 245 ACPNIGQLLVWE----WQSEQY--VMKQQGHSLDMTCLAYSPDGLH 284
           +  + G + +W+     +   Y  +++ QGH     C  +SPDG H
Sbjct: 483 SAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC-KFSPDGNH 527


>AL669934-1|CAI95405.1| 1802|Homo sapiens bromodomain and WD repeat
           domain containing 3 protein.
          Length = 1802

 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 12/192 (6%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GHS +++ +A + +   +  G  D  V+VW             H A
Sbjct: 206 IWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSA 265

Query: 314 TVSGVT-CSANK---KFFVSSSLDGTVRCYDL-TRYRNFR------TLTSPSLVQFSCVA 362
           +++ +  C + K   ++  S+  DGT+  +    +   FR      T  S   VQ SC +
Sbjct: 266 SITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSS 325

Query: 363 LDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
             S G F   G  D V  I+    +  + +  L  H   V ++ F     S R  S S D
Sbjct: 326 FSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRD 385

Query: 422 GTVRLWDCIDRE 433
           GT R+W    +E
Sbjct: 386 GTARIWQYQQQE 397



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 6/124 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+A+   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQD-VFEIFV 382
            + S D  VR + L        L     S + +QF C +   +  +  + G D     + 
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF-CPSTKGTNRYLTSTGADGTICFWQ 296

Query: 383 WSIK 386
           W +K
Sbjct: 297 WHVK 300



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
           CVA D SG     G  D   + +W+   G+LL  L GH A +S +A +    +T +A+ S
Sbjct: 185 CVAFDRSGRRIFTGSDDCL-VKIWATDDGRLLATLRGHSAEISDMAVN--YENTLIAAGS 241

Query: 420 WDGTVRLW 427
            D  VR+W
Sbjct: 242 CDKVVRVW 249



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 49/225 (21%), Positives = 86/225 (38%), Gaps = 29/225 (12%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVW----NTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           + ++C ++S  G+ + TG  D  ++++            +  H  K        + +   
Sbjct: 319 VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLR 378

Query: 327 FVSSSLDGTVRC--YDLTRYRNF-----RTLTSPSL---------VQFSCVALDSSGEFC 370
           FVS S DGT R   Y    +++        +T  +L         ++ + VA D      
Sbjct: 379 FVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTV 438

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
                + F + VW+   G+LL  L GH+  V  L   P      + SA  DG + +WD +
Sbjct: 439 ITAVNN-FLLKVWNSITGQLLHTLSGHDDEVFVLEAHP-FDQRIILSAGHDGNIFIWD-L 495

Query: 431 DREVQCEPI------RLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
           DR  +          + +       F PDG   A +   G++  F
Sbjct: 496 DRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLF 540



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF--ERKSLDL 83
           +++C  +SS    +  GS D   +I+ +       +  L  HTDK++ V F     SL  
Sbjct: 320 QISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRF 379

Query: 84  ITVSRNGQLCLWE 96
           ++ SR+G   +W+
Sbjct: 380 VSGSRDGTARIWQ 392



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++ L  +       L+HTLS  +  +  +   P    I  
Sbjct: 423 KLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIIL 482

Query: 245 ACPNIGQLLVWE----WQSEQY--VMKQQGHSLDMTCLAYSPDGLH 284
           +  + G + +W+     +   Y  +++ QGH     C  +SPDG H
Sbjct: 483 SAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC-KFSPDGNH 527


>AL590031-1|CAI39936.2| 1802|Homo sapiens bromodomain and WD repeat
           domain containing 3 protein.
          Length = 1802

 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 12/192 (6%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GHS +++ +A + +   +  G  D  V+VW             H A
Sbjct: 206 IWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSA 265

Query: 314 TVSGVT-CSANK---KFFVSSSLDGTVRCYDL-TRYRNFR------TLTSPSLVQFSCVA 362
           +++ +  C + K   ++  S+  DGT+  +    +   FR      T  S   VQ SC +
Sbjct: 266 SITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSS 325

Query: 363 LDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
             S G F   G  D V  I+    +  + +  L  H   V ++ F     S R  S S D
Sbjct: 326 FSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRD 385

Query: 422 GTVRLWDCIDRE 433
           GT R+W    +E
Sbjct: 386 GTARIWQYQQQE 397



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 6/124 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+A+   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQD-VFEIFV 382
            + S D  VR + L        L     S + +QF C +   +  +  + G D     + 
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF-CPSTKGTNRYLTSTGADGTICFWQ 296

Query: 383 WSIK 386
           W +K
Sbjct: 297 WHVK 300



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
           CVA D SG     G  D   + +W+   G+LL  L GH A +S +A +    +T +A+ S
Sbjct: 185 CVAFDRSGRRIFTGSDDCL-VKIWATDDGRLLATLRGHSAEISDMAVN--YENTLIAAGS 241

Query: 420 WDGTVRLW 427
            D  VR+W
Sbjct: 242 CDKVVRVW 249



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 49/225 (21%), Positives = 86/225 (38%), Gaps = 29/225 (12%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVW----NTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           + ++C ++S  G+ + TG  D  ++++            +  H  K        + +   
Sbjct: 319 VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLR 378

Query: 327 FVSSSLDGTVRC--YDLTRYRNF-----RTLTSPSL---------VQFSCVALDSSGEFC 370
           FVS S DGT R   Y    +++        +T  +L         ++ + VA D      
Sbjct: 379 FVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTV 438

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
                + F + VW+   G+LL  L GH+  V  L   P      + SA  DG + +WD +
Sbjct: 439 ITAVNN-FLLKVWNSITGQLLHTLSGHDDEVFVLEAHP-FDQRIILSAGHDGNIFIWD-L 495

Query: 431 DREVQCEPI------RLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
           DR  +          + +       F PDG   A +   G++  F
Sbjct: 496 DRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLF 540



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF--ERKSLDL 83
           +++C  +SS    +  GS D   +I+ +       +  L  HTDK++ V F     SL  
Sbjct: 320 QISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRF 379

Query: 84  ITVSRNGQLCLWE 96
           ++ SR+G   +W+
Sbjct: 380 VSGSRDGTARIWQ 392



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++ L  +       L+HTLS  +  +  +   P    I  
Sbjct: 423 KLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIIL 482

Query: 245 ACPNIGQLLVWE----WQSEQY--VMKQQGHSLDMTCLAYSPDGLH 284
           +  + G + +W+     +   Y  +++ QGH     C  +SPDG H
Sbjct: 483 SAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC-KFSPDGNH 527


>AL512504-2|CAI95143.1| 1802|Homo sapiens bromodomain and WD repeat
           domain containing 3 protein.
          Length = 1802

 Score = 60.1 bits (139), Expect = 3e-08
 Identities = 47/192 (24%), Positives = 79/192 (41%), Gaps = 12/192 (6%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W     + +   +GHS +++ +A + +   +  G  D  V+VW             H A
Sbjct: 206 IWATDDGRLLATLRGHSAEISDMAVNYENTLIAAGSCDKVVRVWCLRTCAPVAVLQGHSA 265

Query: 314 TVSGVT-CSANK---KFFVSSSLDGTVRCYDL-TRYRNFR------TLTSPSLVQFSCVA 362
           +++ +  C + K   ++  S+  DGT+  +    +   FR      T  S   VQ SC +
Sbjct: 266 SITSIQFCPSTKGTNRYLTSTGADGTICFWQWHVKTMKFRDRPVKFTERSRPGVQISCSS 325

Query: 363 LDSSGEFCAAGGQD-VFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWD 421
             S G F   G  D V  I+    +  + +  L  H   V ++ F     S R  S S D
Sbjct: 326 FSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRFVSGSRD 385

Query: 422 GTVRLWDCIDRE 433
           GT R+W    +E
Sbjct: 386 GTARIWQYQQQE 397



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 31/124 (25%), Positives = 50/124 (40%), Gaps = 6/124 (4%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFF 327
           GH   + C+A+   G  + TG  D  VK+W T +G    T   H A +S +  +      
Sbjct: 178 GHLSSVYCVAFDRSGRRIFTGSDDCLVKIWATDDGRLLATLRGHSAEISDMAVNYENTLI 237

Query: 328 VSSSLDGTVRCYDLTRYRNFRTL----TSPSLVQFSCVALDSSGEFCAAGGQD-VFEIFV 382
            + S D  VR + L        L     S + +QF C +   +  +  + G D     + 
Sbjct: 238 AAGSCDKVVRVWCLRTCAPVAVLQGHSASITSIQF-CPSTKGTNRYLTSTGADGTICFWQ 296

Query: 383 WSIK 386
           W +K
Sbjct: 297 WHVK 300



 Score = 46.8 bits (106), Expect = 3e-04
 Identities = 25/68 (36%), Positives = 36/68 (52%), Gaps = 3/68 (4%)

Query: 360 CVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASAS 419
           CVA D SG     G  D   + +W+   G+LL  L GH A +S +A +    +T +A+ S
Sbjct: 185 CVAFDRSGRRIFTGSDDCL-VKIWATDDGRLLATLRGHSAEISDMAVN--YENTLIAAGS 241

Query: 420 WDGTVRLW 427
            D  VR+W
Sbjct: 242 CDKVVRVW 249



 Score = 39.1 bits (87), Expect = 0.056
 Identities = 49/225 (21%), Positives = 86/225 (38%), Gaps = 29/225 (12%)

Query: 271 LDMTCLAYSPDGLHVVTGGFDGKVKVW----NTTNGFCFVTFHEHKATVSGVTCSANKKF 326
           + ++C ++S  G+ + TG  D  ++++            +  H  K        + +   
Sbjct: 319 VQISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLR 378

Query: 327 FVSSSLDGTVRC--YDLTRYRNF-----RTLTSPSL---------VQFSCVALDSSGEFC 370
           FVS S DGT R   Y    +++        +T  +L         ++ + VA D      
Sbjct: 379 FVSGSRDGTARIWQYQQQEWKSIVLDMATKMTGNNLPSGEDKITKLKVTMVAWDRYDTTV 438

Query: 371 AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCI 430
                + F + VW+   G+LL  L GH+  V  L   P      + SA  DG + +WD +
Sbjct: 439 ITAVNN-FLLKVWNSITGQLLHTLSGHDDEVFVLEAHP-FDQRIILSAGHDGNIFIWD-L 495

Query: 431 DREVQCEPI------RLNSDALQVAFRPDGEEIAVSTLDGNITFF 469
           DR  +          + +       F PDG   A +   G++  F
Sbjct: 496 DRGTKIRNYFNMIEGQGHGAVFDCKFSPDGNHFACTDSHGHLLLF 540



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 20/73 (27%), Positives = 36/73 (49%), Gaps = 2/73 (2%)

Query: 26  EVTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF--ERKSLDL 83
           +++C  +SS    +  GS D   +I+ +       +  L  HTDK++ V F     SL  
Sbjct: 320 QISCSSFSSGGMFITTGSTDHVIRIYYLGSEVPEKIAELESHTDKVVAVQFCNNGDSLRF 379

Query: 84  ITVSRNGQLCLWE 96
           ++ SR+G   +W+
Sbjct: 380 VSGSRDGTARIWQ 392



 Score = 36.7 bits (81), Expect = 0.30
 Identities = 25/106 (23%), Positives = 49/106 (46%), Gaps = 7/106 (6%)

Query: 185 KVKLTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISEHRISSISVSPPGDWIAF 244
           K+K+T V + + +  ++T  ++ L  +       L+HTLS  +  +  +   P    I  
Sbjct: 423 KLKVTMVAWDRYDTTVITAVNNFLLKVWNSITGQLLHTLSGHDDEVFVLEAHPFDQRIIL 482

Query: 245 ACPNIGQLLVWE----WQSEQY--VMKQQGHSLDMTCLAYSPDGLH 284
           +  + G + +W+     +   Y  +++ QGH     C  +SPDG H
Sbjct: 483 SAGHDGNIFIWDLDRGTKIRNYFNMIEGQGHGAVFDC-KFSPDGNH 527


>AK093221-1|BAC04099.1|  649|Homo sapiens protein ( Homo sapiens
           cDNA FLJ35902 fis, clone TESTI2009577, highly similar to
           NEDD1 PROTEIN. ).
          Length = 649

 Score = 59.3 bits (137), Expect = 5e-08
 Identities = 51/245 (20%), Positives = 103/245 (42%), Gaps = 9/245 (3%)

Query: 226 SEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHV 285
           S H ISSI  S   +++  A  +  +++V   + +   + +       TC+  +   +++
Sbjct: 33  SPHGISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYL 92

Query: 286 VTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYR 345
           V+GG +  V +W+  +     +  +HK  V+ VT + N  +  S SL G +  + +T   
Sbjct: 93  VSGGLNNTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNL 152

Query: 346 N---FRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLLEVLGG-HEAPV 401
           +   F   ++ S+    C     S         D   + +W +            H+AP 
Sbjct: 153 SSTPFGHGSNQSVRHLKCSLFKKS---LLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPA 209

Query: 402 SSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCEPIRLNSDALQVAFRPDGEEIAVST 461
           S + FSP +      +   D  + L+D   +++  + +  ++    V F PDG  +A+ +
Sbjct: 210 SGICFSP-VNELLFVTIGLDKRIILYDTSSKKL-VKTLVADTPLTAVDFMPDGATLAIGS 267

Query: 462 LDGNI 466
             G I
Sbjct: 268 SRGKI 272



 Score = 45.2 bits (102), Expect = 9e-04
 Identities = 48/245 (19%), Positives = 101/245 (41%), Gaps = 9/245 (3%)

Query: 188 LTAVQYHKENKLLVTGFSSGLFFLHEMPDVNLIHTLSISE-HRISSISVSPPGDWIAFAC 246
           ++++ +   N  LVT  SSG   +        +  L ++E  + + ++++    ++    
Sbjct: 37  ISSICWSSNNNFLVTASSSGDKIVVSSCKCKPVPLLELAEGQKQTCVNLNSTSMYLVSGG 96

Query: 247 PNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFV 306
            N   + +W+ +S++     + H   +TC+ Y+ +  ++ +G   G++ + + T      
Sbjct: 97  LN-NTVNIWDLKSKRVHRSLKDHKDQVTCVTYNWNDCYIASGSLSGEIILHSVTTNLSST 155

Query: 307 TF-HEHKATVSGVTCSANKKFFVSSSLD-GTVRCYDLTRYRNFRTLTSPSLVQFSCVALD 364
            F H    +V  + CS  KK  + S  D G V  +D+     +    S      S +   
Sbjct: 156 PFGHGSNQSVRHLKCSLFKKSLLGSVSDNGIVTLWDVNSQSPYHNFDSVHKAPASGICFS 215

Query: 365 SSGEFC-AAGGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGT 423
              E      G D   I ++     KL++ L   + P++++ F P      LA  S  G 
Sbjct: 216 PVNELLFVTIGLDK-RIILYDTSSKKLVKTLVA-DTPLTAVDFMP--DGATLAIGSSRGK 271

Query: 424 VRLWD 428
           +  +D
Sbjct: 272 IYQYD 276


>EF011613-1|ABK41103.1|  513|Homo sapiens CDW3/SMU1 protein.
          Length = 513

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 26/93 (27%), Positives = 54/93 (58%), Gaps = 1/93 (1%)

Query: 250 GQLLVWEWQSEQYVMK-QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF 308
           G++ VW+ QS Q + + ++ HS  +TCL++S D   +++  FD  +++    +G     F
Sbjct: 286 GKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEF 345

Query: 309 HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
             H + V+  T + +  + +S+S DGTV+ +++
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378



 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 48/170 (28%), Positives = 77/170 (45%), Gaps = 13/170 (7%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATV-------SGVT 319
           +GHS  +    ++ DG ++++   DG VK+WN     C  TF    +T        S + 
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVIL 405

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV--QFSCVALDSSGEFCAAGGQDV 377
              N + FV  +   TV   ++ + +  R+ +S       F C AL   GE+    G+D 
Sbjct: 406 LPKNPEHFVVCNRSNTVVIMNM-QGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGED- 463

Query: 378 FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           F ++ +S   GKL   L  HE  V  +A  P      +A+ S DG ++LW
Sbjct: 464 FVLYCFSTVTGKLERTLTVHEKDVIGIAHHP--HQNLIATYSEDGLLKLW 511



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 15/171 (8%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG-----FCFVTFHEHKATVSGVTC-- 320
           G    + C  +SPDG ++VTG  DG ++VWN T G       +            V C  
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMC 271

Query: 321 -SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDV 377
            S + +   + + DG ++ + +   +  R          +C++   DSS    A+  Q  
Sbjct: 272 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQ-- 329

Query: 378 FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             I +  +K GK L+   GH + V+   F  T     + SAS DGTV++W+
Sbjct: 330 -TIRIHGLKSGKTLKEFRGHSSFVNEATF--TQDGHYIISASSDGTVKIWN 377



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 18  RVFKKALDE-VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF 76
           R F++A  + VTCL +S  S  +   S D T +IH ++     T+    GH+  +    F
Sbjct: 300 RRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLK--SGKTLKEFRGHSSFVNEATF 357

Query: 77  ERKSLDLITVSRNGQLCLW 95
            +    +I+ S +G + +W
Sbjct: 358 TQDGHYIISASSDGTVKIW 376


>BC110654-1|AAI10655.1|  513|Homo sapiens smu-1 suppressor of mec-8
           and unc-52 homolog (C. elegans) protein.
          Length = 513

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 26/93 (27%), Positives = 54/93 (58%), Gaps = 1/93 (1%)

Query: 250 GQLLVWEWQSEQYVMK-QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF 308
           G++ VW+ QS Q + + ++ HS  +TCL++S D   +++  FD  +++    +G     F
Sbjct: 286 GKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEF 345

Query: 309 HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
             H + V+  T + +  + +S+S DGTV+ +++
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 15/171 (8%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG-----FCFVTFHEHKATVSGVTC-- 320
           G    + C  +SPDG ++VTG  DG ++VWN T G       +            V C  
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMC 271

Query: 321 -SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDV 377
            S + +   + + DG ++ + +   +  R          +C++   DSS    A+  Q  
Sbjct: 272 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQ-- 329

Query: 378 FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             I +  +K GK L+   GH + V+   F  T     + SAS DGTV++W+
Sbjct: 330 -TIRIHGLKSGKTLKEFRGHSSFVNEATF--TQDGHYIISASSDGTVKIWN 377



 Score = 56.4 bits (130), Expect = 3e-07
 Identities = 47/170 (27%), Positives = 76/170 (44%), Gaps = 13/170 (7%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATV-------SGVT 319
           +GHS  +    ++ DG ++++   DG VK+WN     C  TF    +T        S + 
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVIL 405

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV--QFSCVALDSSGEFCAAGGQDV 377
              N + FV  +   TV   ++ + +  R+ +S       F C AL   GE+    G+D 
Sbjct: 406 LPKNPEHFVVCNRSNTVVIMNM-QGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGED- 463

Query: 378 FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           F ++ +S   GKL   L  HE  V  +A  P      +A+ S D  ++LW
Sbjct: 464 FVLYCFSTVTGKLERTLTVHEKDVIGIAHHP--HQNLIATYSEDALLKLW 511



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 18  RVFKKALDE-VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF 76
           R F++A  + VTCL +S  S  +   S D T +IH ++     T+    GH+  +    F
Sbjct: 300 RRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLK--SGKTLKEFRGHSSFVNEATF 357

Query: 77  ERKSLDLITVSRNGQLCLW 95
            +    +I+ S +G + +W
Sbjct: 358 TQDGHYIISASSDGTVKIW 376


>BC026213-1|AAH26213.1|  529|Homo sapiens F-box and WD repeat domain
           containing 11 protein.
          Length = 529

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 55/218 (25%), Positives = 91/218 (41%), Gaps = 13/218 (5%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+  S + +    GH+  + CL Y  D   +VTG  D  V+VW+   G    T   H  
Sbjct: 251 IWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNE 308

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV-ALDSSGEFCAA 372
            V  +  S      V+ S D ++  +D+    +  TL    +   + V  +D   ++  +
Sbjct: 309 AVLHLRFS--NGLMVTCSKDRSIAVWDMASATDI-TLRRVLVGHRAAVNVVDFDDKYIVS 365

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
              D   I VWS    + +  L GH+  ++ L +   L    + S S D T+RLWD I+ 
Sbjct: 366 ASGD-RTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRL----VVSGSSDNTIRLWD-IEC 419

Query: 433 EVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
              C  +    + L    R D + I     DG I  ++
Sbjct: 420 GA-CLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 456



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 56/231 (24%), Positives = 95/231 (41%), Gaps = 21/231 (9%)

Query: 261 QYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           Q +  +  +S  + CL Y  D   +++G  D  +K+W+ T+  C      H  +V  +  
Sbjct: 218 QRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCL 273

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
             +++  V+ S D TVR +D+       TL   +    + + L  S        +D   I
Sbjct: 274 QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN---EAVLHLRFSNGLMVTCSKD-RSI 329

Query: 381 FVWSIKFG---KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCE 437
            VW +       L  VL GH A V+ + F        + SAS D T+++W        CE
Sbjct: 330 AVWDMASATDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWS----TSTCE 381

Query: 438 PIR-LNSDALQVAFRPDGEEIAVS-TLDGNITFFEPSTCEQTGSVEGRSDL 486
            +R LN     +A     + + VS + D  I  ++         +EG  +L
Sbjct: 382 FVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEEL 432



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 13/96 (13%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN---------TTNGFC 304
           +W+ +    +   +GH   + C+ +  D   +V+G +DGK+KVW+           +  C
Sbjct: 414 LWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLQAALDPRAPASTLC 471

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
             T  EH   V       ++   +SSS D T+  +D
Sbjct: 472 LRTLVEHSGRV--FRLQFDEFQIISSSHDDTILIWD 505


>BC002876-1|AAH02876.1|  513|Homo sapiens smu-1 suppressor of mec-8
           and unc-52 homolog (C. elegans) protein.
          Length = 513

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 26/93 (27%), Positives = 54/93 (58%), Gaps = 1/93 (1%)

Query: 250 GQLLVWEWQSEQYVMK-QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF 308
           G++ VW+ QS Q + + ++ HS  +TCL++S D   +++  FD  +++    +G     F
Sbjct: 286 GKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEF 345

Query: 309 HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
             H + V+  T + +  + +S+S DGTV+ +++
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378



 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 48/170 (28%), Positives = 77/170 (45%), Gaps = 13/170 (7%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATV-------SGVT 319
           +GHS  +    ++ DG ++++   DG VK+WN     C  TF    +T        S + 
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVIL 405

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV--QFSCVALDSSGEFCAAGGQDV 377
              N + FV  +   TV   ++ + +  R+ +S       F C AL   GE+    G+D 
Sbjct: 406 LPKNPEHFVVCNRSNTVVIMNM-QGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGED- 463

Query: 378 FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           F ++ +S   GKL   L  HE  V  +A  P      +A+ S DG ++LW
Sbjct: 464 FVLYCFSTVTGKLERTLTVHEKDVIGIAHHP--HQNLIATYSEDGLLKLW 511



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 15/171 (8%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG-----FCFVTFHEHKATVSGVTC-- 320
           G    + C  +SPDG ++VTG  DG ++VWN T G       +            V C  
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMC 271

Query: 321 -SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDV 377
            S + +   + + DG ++ + +   +  R          +C++   DSS    A+  Q  
Sbjct: 272 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQ-- 329

Query: 378 FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             I +  +K GK L+   GH + V+   F  T     + SAS DGTV++W+
Sbjct: 330 -TIRIHGLKSGKTLKEFRGHSSFVNEATF--TQDGHYIISASSDGTVKIWN 377



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 18  RVFKKALDE-VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF 76
           R F++A  + VTCL +S  S  +   S D T +IH ++     T+    GH+  +    F
Sbjct: 300 RRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLK--SGKTLKEFRGHSSFVNEATF 357

Query: 77  ERKSLDLITVSRNGQLCLW 95
            +    +I+ S +G + +W
Sbjct: 358 TQDGHYIISASSDGTVKIW 376


>AL162590-6|CAI15554.1|  513|Homo sapiens smu-1 suppressor of mec-8
           and unc-52 homolog (C. elegans) protein.
          Length = 513

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 26/93 (27%), Positives = 54/93 (58%), Gaps = 1/93 (1%)

Query: 250 GQLLVWEWQSEQYVMK-QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF 308
           G++ VW+ QS Q + + ++ HS  +TCL++S D   +++  FD  +++    +G     F
Sbjct: 286 GKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEF 345

Query: 309 HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
             H + V+  T + +  + +S+S DGTV+ +++
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378



 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 48/170 (28%), Positives = 77/170 (45%), Gaps = 13/170 (7%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATV-------SGVT 319
           +GHS  +    ++ DG ++++   DG VK+WN     C  TF    +T        S + 
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVIL 405

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV--QFSCVALDSSGEFCAAGGQDV 377
              N + FV  +   TV   ++ + +  R+ +S       F C AL   GE+    G+D 
Sbjct: 406 LPKNPEHFVVCNRSNTVVIMNM-QGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGED- 463

Query: 378 FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           F ++ +S   GKL   L  HE  V  +A  P      +A+ S DG ++LW
Sbjct: 464 FVLYCFSTVTGKLERTLTVHEKDVIGIAHHP--HQNLIATYSEDGLLKLW 511



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 15/171 (8%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG-----FCFVTFHEHKATVSGVTC-- 320
           G    + C  +SPDG ++VTG  DG ++VWN T G       +            V C  
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMC 271

Query: 321 -SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDV 377
            S + +   + + DG ++ + +   +  R          +C++   DSS    A+  Q  
Sbjct: 272 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQ-- 329

Query: 378 FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             I +  +K GK L+   GH + V+   F  T     + SAS DGTV++W+
Sbjct: 330 -TIRIHGLKSGKTLKEFRGHSSFVNEATF--TQDGHYIISASSDGTVKIWN 377



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 18  RVFKKALDE-VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF 76
           R F++A  + VTCL +S  S  +   S D T +IH ++     T+    GH+  +    F
Sbjct: 300 RRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLK--SGKTLKEFRGHSSFVNEATF 357

Query: 77  ERKSLDLITVSRNGQLCLW 95
            +    +I+ S +G + +W
Sbjct: 358 TQDGHYIISASSDGTVKIW 376


>AK001667-1|BAA91822.1|  513|Homo sapiens protein ( Homo sapiens
           cDNA FLJ10805 fis, clone NT2RP4000839, weakly similar to
           VEGETATIBLE INCOMPATIBILITY PROTEIN HET-E-1. ).
          Length = 513

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 26/93 (27%), Positives = 54/93 (58%), Gaps = 1/93 (1%)

Query: 250 GQLLVWEWQSEQYVMK-QQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTF 308
           G++ VW+ QS Q + + ++ HS  +TCL++S D   +++  FD  +++    +G     F
Sbjct: 286 GKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLKSGKTLKEF 345

Query: 309 HEHKATVSGVTCSANKKFFVSSSLDGTVRCYDL 341
             H + V+  T + +  + +S+S DGTV+ +++
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNM 378



 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 48/170 (28%), Positives = 77/170 (45%), Gaps = 13/170 (7%)

Query: 267 QGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATV-------SGVT 319
           +GHS  +    ++ DG ++++   DG VK+WN     C  TF    +T        S + 
Sbjct: 346 RGHSSFVNEATFTQDGHYIISASSDGTVKIWNMKTTECSNTFKSLGSTAGTDITVNSVIL 405

Query: 320 CSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLV--QFSCVALDSSGEFCAAGGQDV 377
              N + FV  +   TV   ++ + +  R+ +S       F C AL   GE+    G+D 
Sbjct: 406 LPKNPEHFVVCNRSNTVVIMNM-QGQIVRSFSSGKREGGDFVCCALSPRGEWIYCVGED- 463

Query: 378 FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           F ++ +S   GKL   L  HE  V  +A  P      +A+ S DG ++LW
Sbjct: 464 FVLYCFSTVTGKLERTLTVHEKDVIGIAHHP--HQNPIATYSEDGLLKLW 511



 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 46/171 (26%), Positives = 75/171 (43%), Gaps = 15/171 (8%)

Query: 268 GHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNG-----FCFVTFHEHKATVSGVTC-- 320
           G    + C  +SPDG ++VTG  DG ++VWN T G       +            V C  
Sbjct: 212 GQKSHVECARFSPDGQYLVTGSVDGFIEVWNFTTGKIRKDLKYQAQDNFMMMDDAVLCMC 271

Query: 321 -SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVAL--DSSGEFCAAGGQDV 377
            S + +   + + DG ++ + +   +  R          +C++   DSS    A+  Q  
Sbjct: 272 FSRDTEMLATGAQDGKIKVWKIQSGQCLRRFERAHSKGVTCLSFSKDSSQILSASFDQ-- 329

Query: 378 FEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWD 428
             I +  +K GK L+   GH + V+   F  T     + SAS DGTV++W+
Sbjct: 330 -TIRIHGLKSGKTLKEFRGHSSFVNEATF--TQDGHYIISASSDGTVKIWN 377



 Score = 33.1 bits (72), Expect = 3.7
 Identities = 22/79 (27%), Positives = 39/79 (49%), Gaps = 3/79 (3%)

Query: 18  RVFKKALDE-VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFF 76
           R F++A  + VTCL +S  S  +   S D T +IH ++     T+    GH+  +    F
Sbjct: 300 RRFERAHSKGVTCLSFSKDSSQILSASFDQTIRIHGLK--SGKTLKEFRGHSSFVNEATF 357

Query: 77  ERKSLDLITVSRNGQLCLW 95
            +    +I+ S +G + +W
Sbjct: 358 TQDGHYIISASSDGTVKIW 376


>AF176022-1|AAF04528.1|  542|Homo sapiens F-box protein Fbw1b
           protein.
          Length = 542

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 55/218 (25%), Positives = 91/218 (41%), Gaps = 13/218 (5%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+  S + +    GH+  + CL Y  D   +VTG  D  V+VW+   G    T   H  
Sbjct: 264 IWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNE 321

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV-ALDSSGEFCAA 372
            V  +  S      V+ S D ++  +D+    +  TL    +   + V  +D   ++  +
Sbjct: 322 AVLHLRFS--NGLMVTCSKDRSIAVWDMASATDI-TLRRVLVGHRAAVNVVDFDDKYIVS 378

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
              D   I VWS    + +  L GH+  ++ L +   L    + S S D T+RLWD I+ 
Sbjct: 379 ASGD-RTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRL----VVSGSSDNTIRLWD-IEC 432

Query: 433 EVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
              C  +    + L    R D + I     DG I  ++
Sbjct: 433 GA-CLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 469



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 56/231 (24%), Positives = 95/231 (41%), Gaps = 21/231 (9%)

Query: 261 QYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           Q +  +  +S  + CL Y  D   +++G  D  +K+W+ T+  C      H  +V  +  
Sbjct: 231 QRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCL 286

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
             +++  V+ S D TVR +D+       TL   +    + + L  S        +D   I
Sbjct: 287 QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN---EAVLHLRFSNGLMVTCSKD-RSI 342

Query: 381 FVWSIKFG---KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCE 437
            VW +       L  VL GH A V+ + F        + SAS D T+++W        CE
Sbjct: 343 AVWDMASATDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWS----TSTCE 394

Query: 438 PIR-LNSDALQVAFRPDGEEIAVS-TLDGNITFFEPSTCEQTGSVEGRSDL 486
            +R LN     +A     + + VS + D  I  ++         +EG  +L
Sbjct: 395 FVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEEL 445



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 13/96 (13%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN---------TTNGFC 304
           +W+ +    +   +GH   + C+ +  D   +V+G +DGK+KVW+           +  C
Sbjct: 427 LWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLQAALDPRAPASTLC 484

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
             T  EH   V       ++   +SSS D T+  +D
Sbjct: 485 LRTLVEHSGRV--FRLQFDEFQIISSSHDDTILIWD 518


>AB033281-1|BAA92331.1|  542|Homo sapiens F-box and WD-repeats
           protein beta-TRCP2 isoform C protein.
          Length = 542

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 55/218 (25%), Positives = 91/218 (41%), Gaps = 13/218 (5%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+  S + +    GH+  + CL Y  D   +VTG  D  V+VW+   G    T   H  
Sbjct: 264 IWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNE 321

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV-ALDSSGEFCAA 372
            V  +  S      V+ S D ++  +D+    +  TL    +   + V  +D   ++  +
Sbjct: 322 AVLHLRFS--NGLMVTCSKDRSIAVWDMASATDI-TLRRVLVGHRAAVNVVDFDDKYIVS 378

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
              D   I VWS    + +  L GH+  ++ L +   L    + S S D T+RLWD I+ 
Sbjct: 379 ASGD-RTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRL----VVSGSSDNTIRLWD-IEC 432

Query: 433 EVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
              C  +    + L    R D + I     DG I  ++
Sbjct: 433 GA-CLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 469



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 56/231 (24%), Positives = 95/231 (41%), Gaps = 21/231 (9%)

Query: 261 QYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           Q +  +  +S  + CL Y  D   +++G  D  +K+W+ T+  C      H  +V  +  
Sbjct: 231 QRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCL 286

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
             +++  V+ S D TVR +D+       TL   +    + + L  S        +D   I
Sbjct: 287 QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN---EAVLHLRFSNGLMVTCSKD-RSI 342

Query: 381 FVWSIKFG---KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCE 437
            VW +       L  VL GH A V+ + F        + SAS D T+++W        CE
Sbjct: 343 AVWDMASATDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWS----TSTCE 394

Query: 438 PIR-LNSDALQVAFRPDGEEIAVS-TLDGNITFFEPSTCEQTGSVEGRSDL 486
            +R LN     +A     + + VS + D  I  ++         +EG  +L
Sbjct: 395 FVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEEL 445



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 13/96 (13%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN---------TTNGFC 304
           +W+ +    +   +GH   + C+ +  D   +V+G +DGK+KVW+           +  C
Sbjct: 427 LWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLQAALDPRAPASTLC 484

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
             T  EH   V       ++   +SSS D T+  +D
Sbjct: 485 LRTLVEHSGRV--FRLQFDEFQIISSSHDDTILIWD 518


>AB033280-1|BAA92330.1|  529|Homo sapiens F-box and WD-repeats
           protein beta-TRCP2 isoform B protein.
          Length = 529

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 55/218 (25%), Positives = 91/218 (41%), Gaps = 13/218 (5%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+  S + +    GH+  + CL Y  D   +VTG  D  V+VW+   G    T   H  
Sbjct: 251 IWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNE 308

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV-ALDSSGEFCAA 372
            V  +  S      V+ S D ++  +D+    +  TL    +   + V  +D   ++  +
Sbjct: 309 AVLHLRFS--NGLMVTCSKDRSIAVWDMASATDI-TLRRVLVGHRAAVNVVDFDDKYIVS 365

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
              D   I VWS    + +  L GH+  ++ L +   L    + S S D T+RLWD I+ 
Sbjct: 366 ASGD-RTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRL----VVSGSSDNTIRLWD-IEC 419

Query: 433 EVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
              C  +    + L    R D + I     DG I  ++
Sbjct: 420 GA-CLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 456



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 56/231 (24%), Positives = 95/231 (41%), Gaps = 21/231 (9%)

Query: 261 QYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           Q +  +  +S  + CL Y  D   +++G  D  +K+W+ T+  C      H  +V  +  
Sbjct: 218 QRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCL 273

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
             +++  V+ S D TVR +D+       TL   +    + + L  S        +D   I
Sbjct: 274 QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN---EAVLHLRFSNGLMVTCSKD-RSI 329

Query: 381 FVWSIKFG---KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCE 437
            VW +       L  VL GH A V+ + F        + SAS D T+++W        CE
Sbjct: 330 AVWDMASATDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWS----TSTCE 381

Query: 438 PIR-LNSDALQVAFRPDGEEIAVS-TLDGNITFFEPSTCEQTGSVEGRSDL 486
            +R LN     +A     + + VS + D  I  ++         +EG  +L
Sbjct: 382 FVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEEL 432



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 13/96 (13%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN---------TTNGFC 304
           +W+ +    +   +GH   + C+ +  D   +V+G +DGK+KVW+           +  C
Sbjct: 414 LWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLQAALDPRAPASTLC 471

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
             T  EH   V       ++   +SSS D T+  +D
Sbjct: 472 LRTLVEHSGRV--FRLQFDEFQIISSSHDDTILIWD 505


>AB033279-1|BAA92329.1|  508|Homo sapiens F-box and WD-repeats
           protein beta-TRCP2 isoform A protein.
          Length = 508

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 55/218 (25%), Positives = 91/218 (41%), Gaps = 13/218 (5%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+  S + +    GH+  + CL Y  D   +VTG  D  V+VW+   G    T   H  
Sbjct: 230 IWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNE 287

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV-ALDSSGEFCAA 372
            V  +  S      V+ S D ++  +D+    +  TL    +   + V  +D   ++  +
Sbjct: 288 AVLHLRFS--NGLMVTCSKDRSIAVWDMASATDI-TLRRVLVGHRAAVNVVDFDDKYIVS 344

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
              D   I VWS    + +  L GH+  ++ L +   L    + S S D T+RLWD I+ 
Sbjct: 345 ASGD-RTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRL----VVSGSSDNTIRLWD-IEC 398

Query: 433 EVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
              C  +    + L    R D + I     DG I  ++
Sbjct: 399 GA-CLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 435



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 56/231 (24%), Positives = 95/231 (41%), Gaps = 21/231 (9%)

Query: 261 QYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           Q +  +  +S  + CL Y  D   +++G  D  +K+W+ T+  C      H  +V  +  
Sbjct: 197 QRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCL 252

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
             +++  V+ S D TVR +D+       TL   +    + + L  S        +D   I
Sbjct: 253 QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN---EAVLHLRFSNGLMVTCSKD-RSI 308

Query: 381 FVWSIKFG---KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCE 437
            VW +       L  VL GH A V+ + F        + SAS D T+++W        CE
Sbjct: 309 AVWDMASATDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWS----TSTCE 360

Query: 438 PIR-LNSDALQVAFRPDGEEIAVS-TLDGNITFFEPSTCEQTGSVEGRSDL 486
            +R LN     +A     + + VS + D  I  ++         +EG  +L
Sbjct: 361 FVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEEL 411



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 13/96 (13%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN---------TTNGFC 304
           +W+ +    +   +GH   + C+ +  D   +V+G +DGK+KVW+           +  C
Sbjct: 393 LWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLQAALDPRAPASTLC 450

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
             T  EH   V       ++   +SSS D T+  +D
Sbjct: 451 LRTLVEHSGRV--FRLQFDEFQIISSSHDDTILIWD 484


>AB014596-1|BAA31671.1|  550|Homo sapiens KIAA0696 protein protein.
          Length = 550

 Score = 58.8 bits (136), Expect = 7e-08
 Identities = 55/218 (25%), Positives = 91/218 (41%), Gaps = 13/218 (5%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKA 313
           +W+  S + +    GH+  + CL Y  D   +VTG  D  V+VW+   G    T   H  
Sbjct: 272 IWDKTSLECLKVLTGHTGSVLCLQY--DERVIVTGSSDSTVRVWDVNTGEVLNTLIHHNE 329

Query: 314 TVSGVTCSANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCV-ALDSSGEFCAA 372
            V  +  S      V+ S D ++  +D+    +  TL    +   + V  +D   ++  +
Sbjct: 330 AVLHLRFS--NGLMVTCSKDRSIAVWDMASATDI-TLRRVLVGHRAAVNVVDFDDKYIVS 386

Query: 373 GGQDVFEIFVWSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDR 432
              D   I VWS    + +  L GH+  ++ L +   L    + S S D T+RLWD I+ 
Sbjct: 387 ASGD-RTIKVWSTSTCEFVRTLNGHKRGIACLQYRDRL----VVSGSSDNTIRLWD-IEC 440

Query: 433 EVQCEPIRLNSDALQVAFRPDGEEIAVSTLDGNITFFE 470
              C  +    + L    R D + I     DG I  ++
Sbjct: 441 GA-CLRVLEGHEELVRCIRFDNKRIVSGAYDGKIKVWD 477



 Score = 44.8 bits (101), Expect = 0.001
 Identities = 56/231 (24%), Positives = 95/231 (41%), Gaps = 21/231 (9%)

Query: 261 QYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTC 320
           Q +  +  +S  + CL Y  D   +++G  D  +K+W+ T+  C      H  +V  +  
Sbjct: 239 QRIQCRSENSKGVYCLQY--DDEKIISGLRDNSIKIWDKTSLECLKVLTGHTGSV--LCL 294

Query: 321 SANKKFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEI 380
             +++  V+ S D TVR +D+       TL   +    + + L  S        +D   I
Sbjct: 295 QYDERVIVTGSSDSTVRVWDVNTGEVLNTLIHHN---EAVLHLRFSNGLMVTCSKD-RSI 350

Query: 381 FVWSIKFG---KLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLWDCIDREVQCE 437
            VW +       L  VL GH A V+ + F        + SAS D T+++W        CE
Sbjct: 351 AVWDMASATDITLRRVLVGHRAAVNVVDFD----DKYIVSASGDRTIKVWS----TSTCE 402

Query: 438 PIR-LNSDALQVAFRPDGEEIAVS-TLDGNITFFEPSTCEQTGSVEGRSDL 486
            +R LN     +A     + + VS + D  I  ++         +EG  +L
Sbjct: 403 FVRTLNGHKRGIACLQYRDRLVVSGSSDNTIRLWDIECGACLRVLEGHEEL 453



 Score = 35.1 bits (77), Expect = 0.92
 Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 13/96 (13%)

Query: 254 VWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWN---------TTNGFC 304
           +W+ +    +   +GH   + C+ +  D   +V+G +DGK+KVW+           +  C
Sbjct: 435 LWDIECGACLRVLEGHEELVRCIRF--DNKRIVSGAYDGKIKVWDLQAALDPRAPASTLC 492

Query: 305 FVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYD 340
             T  EH   V       ++   +SSS D T+  +D
Sbjct: 493 LRTLVEHSGRV--FRLQFDEFQIISSSHDDTILIWD 526


>BC023662-1|AAH23662.2|  475|Homo sapiens RRP9, small subunit (SSU)
           processome component, homolog (yeast) protein.
          Length = 475

 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 10/165 (6%)

Query: 265 KQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK 324
           K  GHS  + C+A S DG ++ +G     + +W   +     TF  H+  VSG+      
Sbjct: 194 KPPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGT 253

Query: 325 KFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS-SGEFC-AAGGQDVFEIFV 382
               S+S D +V+ +++       TL      Q +  ALD+ S E C  AGG+D   + V
Sbjct: 254 HQLYSTSHDRSVKVWNVAENSYVETLFGH---QDAVAALDALSRECCVTAGGRD-GTVRV 309

Query: 383 WSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           W I     L V  GH+  +  +     +    + S + DG+V LW
Sbjct: 310 WKIPEESQL-VFYGHQGSIDCIHL---INEEHMVSGADDGSVALW 350



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 49/213 (23%), Positives = 85/213 (39%), Gaps = 15/213 (7%)

Query: 226 SEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHV 285
           S H +  +++S  G ++A        +L+WE QS Q++    GH   ++ LA+      +
Sbjct: 199 SSH-VLCMAISSDGKYLASG-DRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQL 256

Query: 286 VTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYR 345
            +   D  VKVWN        T   H+  V+ +   + +    +   DGTVR + +    
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEES 316

Query: 346 NFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL----EVLG-----G 396
                     +   C+ L +  E   +G  D   + +W +   + L    E  G     G
Sbjct: 317 QLVFYGHQGSI--DCIHLINE-EHMVSGADD-GSVALWGLSKKRPLALQREAHGLRGEPG 372

Query: 397 HEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            E P    + +  L +  +A+ S    VRLW C
Sbjct: 373 LEQPFWISSVAALLNTDLVATGSHSSCVRLWQC 405



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C+  SS  + LA G +     I   +  +++  Y+ +GH D + G+ F R +  L + 
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHL--YTFTGHRDAVSGLAFRRGTHQLYST 259

Query: 87  SRNGQLCLWEAS 98
           S +  + +W  +
Sbjct: 260 SHDRSVKVWNVA 271


>BC010048-1|AAH10048.1|  475|Homo sapiens RRP9, small subunit (SSU)
           processome component, homolog (yeast) protein.
          Length = 475

 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 10/165 (6%)

Query: 265 KQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK 324
           K  GHS  + C+A S DG ++ +G     + +W   +     TF  H+  VSG+      
Sbjct: 194 KPPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGT 253

Query: 325 KFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS-SGEFC-AAGGQDVFEIFV 382
               S+S D +V+ +++       TL      Q +  ALD+ S E C  AGG+D   + V
Sbjct: 254 HQLYSTSHDRSVKVWNVAENSYVETLFGH---QDAVAALDALSRECCVTAGGRD-GTVRV 309

Query: 383 WSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           W I     L V  GH+  +  +     +    + S + DG+V LW
Sbjct: 310 WKIPEESQL-VFYGHQGSIDCIHL---INEEHMVSGADDGSVALW 350



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 49/213 (23%), Positives = 85/213 (39%), Gaps = 15/213 (7%)

Query: 226 SEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHV 285
           S H +  +++S  G ++A        +L+WE QS Q++    GH   ++ LA+      +
Sbjct: 199 SSH-VLCMAISSDGKYLASG-DRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQL 256

Query: 286 VTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYR 345
            +   D  VKVWN        T   H+  V+ +   + +    +   DGTVR + +    
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEES 316

Query: 346 NFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL----EVLG-----G 396
                     +   C+ L +  E   +G  D   + +W +   + L    E  G     G
Sbjct: 317 QLVFYGHQGSI--DCIHLINE-EHMVSGADD-GSVALWGLSKKRPLALQREAHGLRGEPG 372

Query: 397 HEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            E P    + +  L +  +A+ S    VRLW C
Sbjct: 373 LEQPFWISSVAALLNTDLVATGSHSSCVRLWQC 405



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C+  SS  + LA G +     I   +  +++  Y+ +GH D + G+ F R +  L + 
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHL--YTFTGHRDAVSGLAFRRGTHQLYST 259

Query: 87  SRNGQLCLWEAS 98
           S +  + +W  +
Sbjct: 260 SHDRSVKVWNVA 271


>BC009879-1|AAH09879.1|  475|Homo sapiens RRP9, small subunit (SSU)
           processome component, homolog (yeast) protein.
          Length = 475

 Score = 58.4 bits (135), Expect = 9e-08
 Identities = 47/165 (28%), Positives = 74/165 (44%), Gaps = 10/165 (6%)

Query: 265 KQQGHSLDMTCLAYSPDGLHVVTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANK 324
           K  GHS  + C+A S DG ++ +G     + +W   +     TF  H+  VSG+      
Sbjct: 194 KPPGHSSHVLCMAISSDGKYLASGDRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGT 253

Query: 325 KFFVSSSLDGTVRCYDLTRYRNFRTLTSPSLVQFSCVALDS-SGEFC-AAGGQDVFEIFV 382
               S+S D +V+ +++       TL      Q +  ALD+ S E C  AGG+D   + V
Sbjct: 254 HQLYSTSHDRSVKVWNVAENSYVETLFGH---QDAVAALDALSRECCVTAGGRD-GTVRV 309

Query: 383 WSIKFGKLLEVLGGHEAPVSSLAFSPTLTSTRLASASWDGTVRLW 427
           W I     L V  GH+  +  +     +    + S + DG+V LW
Sbjct: 310 WKIPEESQL-VFYGHQGSIDCIHL---INEEHMVSGADDGSVALW 350



 Score = 47.2 bits (107), Expect = 2e-04
 Identities = 49/213 (23%), Positives = 85/213 (39%), Gaps = 15/213 (7%)

Query: 226 SEHRISSISVSPPGDWIAFACPNIGQLLVWEWQSEQYVMKQQGHSLDMTCLAYSPDGLHV 285
           S H +  +++S  G ++A        +L+WE QS Q++    GH   ++ LA+      +
Sbjct: 199 SSH-VLCMAISSDGKYLASG-DRSKLILIWEAQSCQHLYTFTGHRDAVSGLAFRRGTHQL 256

Query: 286 VTGGFDGKVKVWNTTNGFCFVTFHEHKATVSGVTCSANKKFFVSSSLDGTVRCYDLTRYR 345
            +   D  VKVWN        T   H+  V+ +   + +    +   DGTVR + +    
Sbjct: 257 YSTSHDRSVKVWNVAENSYVETLFGHQDAVAALDALSRECCVTAGGRDGTVRVWKIPEES 316

Query: 346 NFRTLTSPSLVQFSCVALDSSGEFCAAGGQDVFEIFVWSIKFGKLL----EVLG-----G 396
                     +   C+ L +  E   +G  D   + +W +   + L    E  G     G
Sbjct: 317 QLVFYGHQGSI--DCIHLINE-EHMVSGADD-GSVALWGLSKKRPLALQREAHGLRGEPG 372

Query: 397 HEAPVSSLAFSPTLTSTRLASASWDGTVRLWDC 429
            E P    + +  L +  +A+ S    VRLW C
Sbjct: 373 LEQPFWISSVAALLNTDLVATGSHSSCVRLWQC 405



 Score = 33.9 bits (74), Expect = 2.1
 Identities = 18/72 (25%), Positives = 35/72 (48%), Gaps = 2/72 (2%)

Query: 27  VTCLDWSSCSRLLAVGSKDTTTKIHTVEYLENITMYSLSGHTDKIIGVFFERKSLDLITV 86
           V C+  SS  + LA G +     I   +  +++  Y+ +GH D + G+ F R +  L + 
Sbjct: 202 VLCMAISSDGKYLASGDRSKLILIWEAQSCQHL--YTFTGHRDAVSGLAFRRGTHQLYST 259

Query: 87  SRNGQLCLWEAS 98
           S +  + +W  +
Sbjct: 260 SHDRSVKVWNVA 271


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.318    0.133    0.395 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 110,509,932
Number of Sequences: 224733
Number of extensions: 4718798
Number of successful extensions: 31841
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 690
Number of HSP's successfully gapped in prelim test: 543
Number of HSP's that attempted gapping in prelim test: 21308
Number of HSP's gapped (non-prelim): 7616
length of query: 746
length of database: 73,234,838
effective HSP length: 95
effective length of query: 651
effective length of database: 51,885,203
effective search space: 33777267153
effective search space used: 33777267153
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 69 (31.9 bits)

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