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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000829-TA|BGIBMGA000829-PA|IPR004871|CPSF A subunit,
C-terminal, IPR011046|WD40-like, IPR003006|Immunoglobulin/major
histocompatibility complex
         (1218 letters)

Database: nematostella 
           59,808 sequences; 16,821,457 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

SB_12239| Best HMM Match : CPSF_A (HMM E-Value=1.2)                   677   0.0  
SB_46407| Best HMM Match : CPSF_A (HMM E-Value=3.8e-11)               164   4e-40
SB_57383| Best HMM Match : No HMM Matches (HMM E-Value=.)              77   9e-14
SB_11717| Best HMM Match : No HMM Matches (HMM E-Value=.)              70   1e-11
SB_54215| Best HMM Match : No HMM Matches (HMM E-Value=.)              43   0.001
SB_47303| Best HMM Match : CPSF_A (HMM E-Value=0)                      37   0.087
SB_52352| Best HMM Match : No HMM Matches (HMM E-Value=.)              36   0.15 
SB_47874| Best HMM Match : Keratin_B2 (HMM E-Value=4.9)                35   0.46 
SB_22182| Best HMM Match : DUF1626 (HMM E-Value=1.7)                   32   2.5  
SB_40561| Best HMM Match : Keratin_B2 (HMM E-Value=1.1)                30   10.0 
SB_27305| Best HMM Match : MFMR (HMM E-Value=0.53)                     30   10.0 

>SB_12239| Best HMM Match : CPSF_A (HMM E-Value=1.2)
          Length = 864

 Score =  677 bits (1672), Expect = 0.0
 Identities = 322/421 (76%), Positives = 361/421 (85%), Gaps = 21/421 (4%)

Query: 1   MYLYNLTLQGSSAITHAVHGNFSGTKQQEIIISRGKTLELLRPDPNTGKVHTFMKIEIFG 60
           M+LY LTLQ +SAI + +HGNFSGTKQQEI++SRGK +ELLR DPNTGKV   + IE+FG
Sbjct: 1   MHLYALTLQRASAINNTIHGNFSGTKQQEIVVSRGKFVELLRTDPNTGKVFPVLAIEMFG 60

Query: 61  VVRSIMAFRLTGGTKDYIVVGSDSGRIIILEYIPTKNILEKVHQETFGKSGCRRIVPGQY 120
           +VR ++AFRLTGG+KD+IVVGSDSGRI+ILEYIP+KN+ EKVHQETFGKSGCRRIVPGQY
Sbjct: 61  IVRDLIAFRLTGGSKDFIVVGSDSGRIVILEYIPSKNVFEKVHQETFGKSGCRRIVPGQY 120

Query: 121 LSIDPKGRAVMIGAIEKQKLVYILNRDAEARLTISSPLEAHKSNTLVYHMVGVDVGFENP 180
           L+ DPKGRA+MIGAIEKQKLVYI+NRD+ ARLTISSPLEAHKS+TLVYHMVGVD GFENP
Sbjct: 121 LAADPKGRAIMIGAIEKQKLVYIMNRDSAARLTISSPLEAHKSHTLVYHMVGVDAGFENP 180

Query: 181 MFACLEIDYEEADSDPTGEAAQKTQQTLTFYELDLGLNHVVRKYSEPLEEHANFLITVPG 240
           MFACLE+DYEEAD+D TGEAAQ TQQTLTFYELDLGLNHVVRKYSEPLEEH N LI VPG
Sbjct: 181 MFACLEMDYEEADTDHTGEAAQTTQQTLTFYELDLGLNHVVRKYSEPLEEHGNLLIAVPG 240

Query: 241 GNDGPSGVLICSENYLTYKNLGDQHDIRCPIPRRRNDLDDPERGMIFVCSATHKTKSMFF 300
           G+DGPSGVL+CSENYLTYKN GDQ DIR PIPRR                     KSMFF
Sbjct: 241 GSDGPSGVLVCSENYLTYKNFGDQPDIRMPIPRR---------------------KSMFF 279

Query: 301 FLAQTEQGDIFKITIETDEDMVTEIKLKYFDTVPVATSMCVLKTGFLFVACEFGNHYLYQ 360
           FL QTEQGDIFKIT+ETDEDMVTEI++KYFDTVP A SMCVLKTGFLF A EFGNHYLYQ
Sbjct: 280 FLVQTEQGDIFKITLETDEDMVTEIRMKYFDTVPPAVSMCVLKTGFLFTASEFGNHYLYQ 339

Query: 361 IAHLGDEDDEPEFSSAMPLEEGDTFFFAPRPLRNLVLVDEMDSLSPILACHVADLAGEDT 420
           IAHLGD+DDE EFSS M LEEG TFFF PR L+NLVLVDE++SL+PI+ C V+++A  + 
Sbjct: 340 IAHLGDDDDELEFSSTMELEEGTTFFFQPRGLKNLVLVDELESLAPIMNCQVSEMAVSEL 399

Query: 421 P 421
           P
Sbjct: 400 P 400



 Score =  348 bits (855), Expect = 2e-95
 Identities = 167/226 (73%), Positives = 196/226 (86%), Gaps = 6/226 (2%)

Query: 443 EVAEMAVSELPGSPNAVWTVRRNKDEEYDSYIIVSFVNATLVLSIGETVEEVTDSGFLGT 502
           +V+EMAVSELPG+PNAVWTV+    +E+D+YI+VSF+NATLVLSIGETVEEVTDSGFLGT
Sbjct: 390 QVSEMAVSELPGNPNAVWTVKHTTADEFDAYIVVSFINATLVLSIGETVEEVTDSGFLGT 449

Query: 503 TPTLSCHAMGNDALVQVYPDGIRHIRADKRVNEWKAPGKKSIVRCAVNQRQVVIALTGGE 562
           TPTLSC  +G +ALVQ+YPDGIRHIRADKRVNEWKAPGKK+IV+ AVN+RQVVIALTGGE
Sbjct: 450 TPTLSCSQLGEEALVQIYPDGIRHIRADKRVNEWKAPGKKTIVKSAVNERQVVIALTGGE 509

Query: 563 LVYFEMDPTGQLNEYTERKKLSSDVCCMALGSVAAGEQRAWFLAVGLNDNTVRIISLDPA 622
           +VYFEMD +GQLNEYTERK++S+DV CMALG++  GE R+ FLA+GL+DNTVRIISLDP 
Sbjct: 510 VVYFEMDSSGQLNEYTERKEMSADVQCMALGTILHGELRSRFLAIGLSDNTVRIISLDPQ 569

Query: 623 DCLSPRSMQALPAGAESLCIIEQPFESGAKS------ALHLNIGLS 662
           DCL+P SMQALPA  ESLCI+E   + GA+S       L LNIGLS
Sbjct: 570 DCLTPLSMQALPAMPESLCIVEMGGKEGAESEGGSMGGLFLNIGLS 615



 Score =  244 bits (597), Expect = 3e-64
 Identities = 135/257 (52%), Positives = 172/257 (66%), Gaps = 23/257 (8%)

Query: 703 AVLAVSSRTWLGYHYQNRFHLTPLSYECLEYAAGFSSEQCTEGIVAISSNTLRILALEKL 762
           +VLA+SSR+WL Y +Q+R HLTPLSYE LEYA+GFSSEQC EGIVAI+ NTLRILALEKL
Sbjct: 615 SVLAMSSRSWLSYTHQSRVHLTPLSYETLEYASGFSSEQCPEGIVAIAGNTLRILALEKL 674

Query: 763 GAVFNQTFVPLEYTPRKFIINSDNNHIIVLETDHNAYTEEMKKHRRIQMAQEMREXXXXX 822
           GAVFNQ   PL+YTPRKF+I+S  N ++V+ETDHN YT+  ++ R+ QMA+EM E     
Sbjct: 675 GAVFNQVATPLKYTPRKFVIHSPTNTLVVIETDHNTYTDAAREERKQQMAEEMVEMASE- 733

Query: 823 XPEEQQLANEMADAFLSDTLPEYIFSSPKAGAGMWASLIRVVDMGIGGGQPNTLFRLPLE 882
             EE++LA + A  FLS+ L E  F SPKAG GMWAS+IRV+D   G     T   + L+
Sbjct: 734 --EEKELAAQAAAEFLSEELSEQQFGSPKAGTGMWASVIRVLDPIKG----ETHDVVQLD 787

Query: 883 QNEAAVSLCI--------VRWAA-----HAEHAQPHLVVGVAKDLILSPRSCTEGSLHVY 929
           QNEAA S+C+         R++       A      ++VG AKD+ LSPRSC+ G L+ Y
Sbjct: 788 QNEAAFSVCVRVFIDRLFFRYSVCVCSFSARPDDTFVIVGTAKDMALSPRSCSTGYLYAY 847

Query: 930 KIYGNTG---KLELVHK 943
           ++        KLE  HK
Sbjct: 848 RLVQQPSGGIKLEFQHK 864


>SB_46407| Best HMM Match : CPSF_A (HMM E-Value=3.8e-11)
          Length = 242

 Score =  164 bits (398), Expect = 4e-40
 Identities = 75/148 (50%), Positives = 106/148 (71%), Gaps = 5/148 (3%)

Query: 889  SLCIVRWAAHAEHAQPHLVVGVAKDLILSPRSCTEGSLHVYKIYGNTG---KLELVHKTP 945
            S+C+  ++A  +     ++VG AKD+ LSPRSC+ G L+ Y++        KLE  HKT 
Sbjct: 51   SVCVCSFSARPDDT--FVIVGTAKDMALSPRSCSTGYLYAYRLVQQPSGGIKLEFQHKTE 108

Query: 946  VDEYPGAIAAFNGRLLAGVGRMLRLYDIGRRKLLRKCENRHIPNLIADIKTIGQRIFVSD 1005
            VD+ P A+  F GRLLAG+GR+LR+YDIG++K+LRKCEN+ +PN I +I ++G RI VSD
Sbjct: 109  VDDVPAALEPFQGRLLAGIGRLLRVYDIGKKKMLRKCENKKLPNFICNINSMGTRIVVSD 168

Query: 1006 VQESVFCVKHKKRENQLIIFADDTNPRW 1033
            +QES   VK+K R+NQL++FADD NP +
Sbjct: 169  IQESFHFVKYKPRDNQLVVFADDVNPSY 196


>SB_57383| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 46

 Score = 77.0 bits (181), Expect = 9e-14
 Identities = 34/46 (73%), Positives = 41/46 (89%)

Query: 1173 NVIDGDLCEQFNSLDPGKQKAIAGDLERTPAEVSKKLEDIRTRYAF 1218
            +V+DGDLCE +NSLD  K++ IA +L+RTPAEVSKKLEDIRTRYAF
Sbjct: 1    SVVDGDLCEHYNSLDYSKRRTIAEELDRTPAEVSKKLEDIRTRYAF 46


>SB_11717| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 173

 Score = 70.1 bits (164), Expect = 1e-11
 Identities = 30/47 (63%), Positives = 41/47 (87%)

Query: 1091 DVVVNFHVGETVTSLQRATLIPGGSEALLYATISGSLGVLLPFTSRE 1137
            + + N+ VGETV SLQ+ATLIPGGSE+L++ T+SG +G+L+PFTSRE
Sbjct: 127  ETMCNYFVGETVLSLQKATLIPGGSESLVFTTLSGGVGMLVPFTSRE 173



 Score = 61.3 bits (142), Expect = 5e-09
 Identities = 26/36 (72%), Positives = 29/36 (80%)

Query: 1057 MRLPQSVSDDVDEDPTGNKALWDRGLLNGASQKGDV 1092
            +RLP   SDDVDEDPTG KA WDRGLLNGA QK ++
Sbjct: 56   VRLPSGSSDDVDEDPTGTKAFWDRGLLNGAQQKREM 91



 Score = 38.7 bits (86), Expect = 0.028
 Identities = 14/22 (63%), Positives = 18/22 (81%)

Query: 1033 WITNSCILDYDTIAVSDKFGNV 1054
            W+T  C LDYDT+A +DKFGN+
Sbjct: 2    WLTCCCYLDYDTLAGADKFGNI 23


>SB_54215| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 695

 Score = 43.2 bits (97), Expect = 0.001
 Identities = 47/164 (28%), Positives = 69/164 (42%), Gaps = 28/164 (17%)

Query: 397 LVDEMDSLSPILACHVADLAGEDTPQVYLACGRGPRSSLRALRHGLEVAEMAVSELPGSP 456
           +++   +L PI+   V DL  +   Q+    G     SLR +R+G+ + E A  +L G  
Sbjct: 289 VMETFTNLGPIVDMVVVDLERQGQGQLVTCSGAKKEGSLRIIRNGIGIHEHATIDLAG-- 346

Query: 457 NAVWTVRRNKDEEYDSYIIVSFVNATLVLSIGETVEEVTDSGFLGTTPTLSCHAMGNDAL 516
                            I+V      L LS GE VEE    GF     T     +    L
Sbjct: 347 -----------------IMV------LSLS-GEEVEETEIPGFSDDQQTYYSGNVTGAQL 382

Query: 517 VQVYPDGIRHIRADKR--VNEWKAPGKKSIVRCAVNQRQVVIAL 558
           +QV    +R +  + R  V+EWK P  K+I   + N  QVV A+
Sbjct: 383 IQVTAASVRLVNCETRQLVSEWKHPSAKNISVASCNTEQVVAAV 426



 Score = 39.5 bits (88), Expect = 0.016
 Identities = 27/124 (21%), Positives = 60/124 (48%), Gaps = 1/124 (0%)

Query: 656 HLNIGLSNGVLLRTTLDSVSGDLADTRTRYLGSRPVKLFKVRVQAAEAVLAVSSRTWLGY 715
           +L   L +G L   T+D  +G LA+ +   LG++P  L   +  +   V A S R  + Y
Sbjct: 444 YLLCALGDGTLFYFTMDPSTGALAECKKVTLGTQPTMLRTFKSLSTVNVFACSDRPTVIY 503

Query: 716 HYQNRFHLTPLSYECLEYAAGFSSEQCTEGIVAISSNTLRILALEKLGAVFNQTFVPLEY 775
              ++   + ++ + + +    +S+   + +   +  +L I  ++++  +  +T VPL  
Sbjct: 504 SSNHKLVFSNVNLKEVNFMCPLNSQGYPDSLALANDGSLTIGTIDEIQKLHIRT-VPLGE 562

Query: 776 TPRK 779
           +PR+
Sbjct: 563 SPRR 566



 Score = 34.3 bits (75), Expect = 0.61
 Identities = 25/88 (28%), Positives = 44/88 (50%), Gaps = 6/88 (6%)

Query: 4  YNLTLQGSSAITHAVHGNFSGTKQQEIIISRGKTLELLRPDPNTGKVHTFMKIEIFGVVR 63
          Y +T Q  +A+  AV GNF+G     ++I++   LE+    P    +   + + ++G V 
Sbjct: 5  YVVTAQKPTAVNAAVVGNFTGPDDLNLVIAKNTRLEIHLVTPE--GLRPMLDVGLYGSVG 62

Query: 64 SIMAFRLTGGTKDYIVVGSDSGRIIILE 91
           +  FR      D I   SD+G+I I++
Sbjct: 63 VMELFR----PPDRIGRPSDTGQIGIID 86


>SB_47303| Best HMM Match : CPSF_A (HMM E-Value=0)
          Length = 1291

 Score = 37.1 bits (82), Expect = 0.087
 Identities = 26/106 (24%), Positives = 50/106 (47%), Gaps = 13/106 (12%)

Query: 467 DEEYDSYIIVSFVNATLVLSIGETVEEVTDSGFLGTTPTLSCHAMGNDALVQVYP----- 521
           +E+Y S++I+S  +++++L   + + EV  SGF     T+     GN + +   P     
Sbjct: 180 NEKYHSFLILSREDSSMILKTEQEIMEVDQSGFSTQCATIYAGNFGNGSYILQLPCISEV 239

Query: 522 DGIRHIRADKRVNEWKAPGKKSIVRCAVNQRQVVIALTGGELVYFE 567
           + ++HI  D         G  +IV C+V     V+ +  G ++  E
Sbjct: 240 NQLQHIPMDS--------GLSNIVWCSVCDPYAVLLMADGSVILIE 277


>SB_52352| Best HMM Match : No HMM Matches (HMM E-Value=.)
          Length = 645

 Score = 36.3 bits (80), Expect = 0.15
 Identities = 24/80 (30%), Positives = 44/80 (55%), Gaps = 5/80 (6%)

Query: 58  IFGVVRSIMAFRLTGGTKDYIVVGSDSGRIIILEYIPTKNILE--KVH--QETFGKSGCR 113
           +FG + S+ A RL G T+D +++     ++ I++Y P K+ ++   +H  ++   KS C 
Sbjct: 364 LFGNIESLHAIRLAGNTRDSLLMSFKDAKLSIVDYDPGKHDIKTRSLHFFEDEKIKSHCL 423

Query: 114 RIVPGQYLSIDPKGR-AVMI 132
                  + IDP+ R AVM+
Sbjct: 424 AQDRAPVVRIDPERRCAVML 443


>SB_47874| Best HMM Match : Keratin_B2 (HMM E-Value=4.9)
          Length = 253

 Score = 34.7 bits (76), Expect = 0.46
 Identities = 14/56 (25%), Positives = 27/56 (48%)

Query: 742 CTEGIVAISSNTLRILALEKLGAVFNQTFVPLEYTPRKFIINSDNNHIIVLETDHN 797
           C   +  + ++TL I+    L  ++N T   +  +P    + S  +H ++  TDHN
Sbjct: 146 CNHTLTTMCNHTLTIMCNHTLTTMYNHTLTTILQSPTDHHVQSHTDHHVLSNTDHN 201


>SB_22182| Best HMM Match : DUF1626 (HMM E-Value=1.7)
          Length = 357

 Score = 32.3 bits (70), Expect = 2.5
 Identities = 38/131 (29%), Positives = 59/131 (45%), Gaps = 8/131 (6%)

Query: 580 RKKLSSDVCCMALGSVAAGEQRAWFLAVGLNDNTVRIISLDPADCLSPRSMQALPAGAES 639
           RK  SS+   +ALG+    E R WFL V   D  + I+      CL  +++    +GA  
Sbjct: 141 RKIFSSEERYLALGTTIDLENRRWFL-VKKTDIVLHIVK---GFCLMSKTI--FFSGARE 194

Query: 640 LCIIEQPFESGAKSALHLNIGLSNGVLLRTTLDSVSGDLADTRTRYLGSRPVKLFKVRVQ 699
           +    Q + + AK    L+  +S+ V +   +  +  +LA   T     R  K+ K RV 
Sbjct: 195 IFKQGQRWLTQAKEYYELDGHVSDYVQIEQDVSQLYKELAKLETD--KERKCKMHKRRVD 252

Query: 700 AAEAVLAVSSR 710
              AVLA S +
Sbjct: 253 VLCAVLADSMK 263


>SB_40561| Best HMM Match : Keratin_B2 (HMM E-Value=1.1)
          Length = 1139

 Score = 30.3 bits (65), Expect = 10.0
 Identities = 20/76 (26%), Positives = 35/76 (46%), Gaps = 4/76 (5%)

Query: 274 RRNDLDDPERGMIFVC-SATHKTKSMFFFLAQTEQGDIFKITIETDED---MVTEIKLKY 329
           R+  L  P +  ++ C S  HK    F F + +  G+IF+I I        M + +K+KY
Sbjct: 63  RKAKLFLPVKTSVYRCVSKEHKNMRCFLFHSVSTSGEIFEILICKSHVIGWMTSSLKIKY 122

Query: 330 FDTVPVATSMCVLKTG 345
           + +  +     + K G
Sbjct: 123 YQSANIVEFDVLTKNG 138


>SB_27305| Best HMM Match : MFMR (HMM E-Value=0.53)
          Length = 823

 Score = 30.3 bits (65), Expect = 10.0
 Identities = 16/50 (32%), Positives = 25/50 (50%), Gaps = 3/50 (6%)

Query: 290 SATHKTKSMFFFLAQTEQGDIFKITIETDED---MVTEIKLKYFDTVPVA 336
           S  HK K  F F + +  G+ F+I I        M + +K+KY+ T  +A
Sbjct: 710 SKEHKNKRCFLFHSVSTSGEFFEILICKSHVIGWMTSSLKIKYYQTANIA 759


  Database: nematostella
    Posted date:  Oct 22, 2007  1:22 PM
  Number of letters in database: 16,821,457
  Number of sequences in database:  59,808
  
Lambda     K      H
   0.320    0.136    0.403 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 41,843,123
Number of Sequences: 59808
Number of extensions: 1825263
Number of successful extensions: 3528
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 3501
Number of HSP's gapped (non-prelim): 25
length of query: 1218
length of database: 16,821,457
effective HSP length: 90
effective length of query: 1128
effective length of database: 11,438,737
effective search space: 12902895336
effective search space used: 12902895336
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 65 (30.3 bits)

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