Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000828-TA|BGIBMGA000828-PA|IPR008994|Nucleic
acid-binding, OB-fold, IPR001208|MCM, IPR008049|MCM protein 6
(799 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q14566 Cluster: DNA replication licensing factor MCM6; ... 975 0.0
UniRef50_Q3E8H3 Cluster: Uncharacterized protein At5g44635.1; n=... 641 0.0
UniRef50_P49731 Cluster: DNA replication licensing factor mcm6; ... 609 e-173
UniRef50_Q239F7 Cluster: MCM2/3/5 family protein; n=1; Tetrahyme... 596 e-169
UniRef50_A3LR24 Cluster: DNA replication licensing factor, MCM6 ... 585 e-165
UniRef50_P53091 Cluster: DNA replication licensing factor MCM6; ... 583 e-165
UniRef50_Q1ZXM5 Cluster: MCM family protein; n=2; Dictyostelium ... 580 e-164
UniRef50_Q6CED4 Cluster: Yarrowia lipolytica chromosome B of str... 567 e-160
UniRef50_A0EIN0 Cluster: Chromosome undetermined scaffold_99, wh... 561 e-158
UniRef50_Q2TWS7 Cluster: DNA replication licensing factor; n=14;... 554 e-156
UniRef50_Q01GI0 Cluster: Mini-chromosome maintenance protein MCM... 552 e-155
UniRef50_A6QU77 Cluster: Putative uncharacterized protein; n=1; ... 516 e-144
UniRef50_Q5BGV2 Cluster: Putative uncharacterized protein; n=1; ... 513 e-144
UniRef50_A2DDL4 Cluster: MCM2/3/5 family protein; n=1; Trichomon... 500 e-140
UniRef50_UPI000049880B Cluster: DNA replication licensing factor... 495 e-138
UniRef50_Q4Q826 Cluster: DNA replication licensing factor, putat... 476 e-133
UniRef50_Q8SRX5 Cluster: DNA REPLICATION LICENSING FACTOR OF THE... 459 e-127
UniRef50_A7APV6 Cluster: MCM2/3/5 family protein; n=1; Babesia b... 441 e-122
UniRef50_A5K2F8 Cluster: DNA replication licensing factor MCM6, ... 430 e-119
UniRef50_Q4SNX1 Cluster: Chromosome 15 SCAF14542, whole genome s... 405 e-111
UniRef50_Q4UDH3 Cluster: Replication licensing factor, putative;... 376 e-102
UniRef50_P30665 Cluster: Cell division control protein 54; n=18;... 328 3e-88
UniRef50_A1CSW6 Cluster: DNA replication licensing factor MCM4; ... 322 3e-86
UniRef50_Q9UXG1 Cluster: Minichromosome maintenance protein MCM;... 321 5e-86
UniRef50_Q5K7N5 Cluster: DNA unwinding-related protein, putative... 316 1e-84
UniRef50_A4SAW6 Cluster: Predicted protein; n=1; Ostreococcus lu... 312 2e-83
UniRef50_P41389 Cluster: DNA replication licensing factor mcm5; ... 312 2e-83
UniRef50_A7P7V8 Cluster: Chromosome chr3 scaffold_8, whole genom... 304 6e-81
UniRef50_A0DAC7 Cluster: Chromosome undetermined scaffold_43, wh... 291 5e-77
UniRef50_Q552W6 Cluster: MCM family protein; n=2; Dictyostelium ... 288 3e-76
UniRef50_Q8ZY88 Cluster: DNA replication licensing factor; n=6; ... 288 3e-76
UniRef50_UPI00006CCA0D Cluster: MCM2/3/5 family protein; n=1; Te... 287 8e-76
UniRef50_Q22RW4 Cluster: MCM2/3/5 family protein; n=3; Eukaryota... 286 2e-75
UniRef50_Q5CPI6 Cluster: DNA replication licensing factor MCM6-l... 284 6e-75
UniRef50_UPI00006CF347 Cluster: MCM2/3/5 family protein; n=1; Te... 282 2e-74
UniRef50_P29496 Cluster: Minichromosome maintenance protein 5; n... 282 2e-74
UniRef50_Q4X1F6 Cluster: DNA replication licensing factor Mcm7, ... 279 2e-73
UniRef50_UPI00004991C5 Cluster: DNA replication licensing factor... 279 2e-73
UniRef50_Q8SRS4 Cluster: DNA REPLICATION LICENSING FACTOR OF THE... 279 3e-73
UniRef50_P33991 Cluster: DNA replication licensing factor MCM4; ... 279 3e-73
UniRef50_Q979U9 Cluster: DNA replication initiator; n=4; Thermop... 277 9e-73
UniRef50_Q5CJF4 Cluster: DNA replication licensing factor mcm5; ... 276 1e-72
UniRef50_Q54RU0 Cluster: MCM family protein; n=1; Dictyostelium ... 276 2e-72
UniRef50_A2DCM5 Cluster: MCM2/3/5 family protein; n=1; Trichomon... 276 2e-72
UniRef50_P33992 Cluster: DNA replication licensing factor MCM5; ... 275 3e-72
UniRef50_P30666 Cluster: DNA replication licensing factor mcm3; ... 275 3e-72
UniRef50_UPI00015BB272 Cluster: replicative DNA helicase Mcm; n=... 275 3e-72
UniRef50_A0BS22 Cluster: Chromosome undetermined scaffold_124, w... 275 3e-72
UniRef50_Q9YFR1 Cluster: Minichromosome maintenance protein; n=2... 274 8e-72
UniRef50_P43299 Cluster: Protein PROLIFERA; n=10; Eukaryota|Rep:... 273 1e-71
UniRef50_P38132 Cluster: DNA replication licensing factor CDC47;... 272 2e-71
UniRef50_Q2NHD8 Cluster: Predicted minichromosome maintenance pr... 271 6e-71
UniRef50_P25205 Cluster: DNA replication licensing factor MCM3; ... 270 1e-70
UniRef50_A7AU57 Cluster: DNA replication licensing factor MCM4; ... 269 2e-70
UniRef50_Q5CH83 Cluster: Minichromosome maintenance protein mcm7... 267 7e-70
UniRef50_Q5KFJ3 Cluster: ATP dependent DNA helicase, putative; n... 267 9e-70
UniRef50_A0RYB8 Cluster: Cdc46/Mcm DNA replication licensing fac... 267 9e-70
UniRef50_Q6R8Y2 Cluster: Minichromosome maintenance protein 5; n... 266 1e-69
UniRef50_A2FUI9 Cluster: MCM2/3/5 family protein; n=1; Trichomon... 265 4e-69
UniRef50_Q01BJ5 Cluster: Minichromosome maintenance family prote... 264 6e-69
UniRef50_Q8SSE5 Cluster: DNA REPLICATION LICENSING FACTOR OF THE... 264 6e-69
UniRef50_A7F6V0 Cluster: Putative uncharacterized protein; n=2; ... 264 6e-69
UniRef50_Q9GR06 Cluster: DNA replication licensing factor MCM4; ... 262 2e-68
UniRef50_Q21902 Cluster: DNA replication licensing factor mcm-5;... 262 2e-68
UniRef50_P29469 Cluster: DNA replication licensing factor MCM2; ... 262 3e-68
UniRef50_Q54LI2 Cluster: MCM family protein; n=2; Eukaryota|Rep:... 261 6e-68
UniRef50_Q7ZAA5 Cluster: Mcm protein; n=5; Euryarchaeota|Rep: Mc... 260 8e-68
UniRef50_Q5KDY4 Cluster: DNA replication licensing factor cdc19 ... 260 1e-67
UniRef50_Q8WSL5 Cluster: DNA replication licensing factor MCM5; ... 258 3e-67
UniRef50_A2F017 Cluster: MCM2/3/5 family protein; n=1; Trichomon... 252 2e-65
UniRef50_P33993 Cluster: DNA replication licensing factor MCM7; ... 252 4e-65
UniRef50_A0B5T2 Cluster: MCM family protein; n=1; Methanosaeta t... 250 1e-64
UniRef50_Q7QZN0 Cluster: GLP_680_44640_47504; n=1; Giardia lambl... 250 1e-64
UniRef50_Q3SAC5 Cluster: DNA replication licensing factor MCM re... 250 1e-64
UniRef50_UPI00004994EB Cluster: DNA replication licensing factor... 249 2e-64
UniRef50_Q9LPD9 Cluster: T12C22.19 protein; n=18; Eukaryota|Rep:... 249 2e-64
UniRef50_P49736 Cluster: DNA replication licensing factor MCM2; ... 247 8e-64
UniRef50_Q8SRF0 Cluster: DNA REPLICATION LICENSING FACTOR OF THE... 247 1e-63
UniRef50_A2DN04 Cluster: MCM2/3/5 family protein; n=1; Trichomon... 246 2e-63
UniRef50_A7AS39 Cluster: DNA replication licensing factor MCM5, ... 246 2e-63
UniRef50_Q5CNK7 Cluster: DNA replication licensing factor MCM2; ... 245 3e-63
UniRef50_Q8TJF6 Cluster: Mcm protein; n=5; Methanosarcinaceae|Re... 244 6e-63
UniRef50_P24279 Cluster: DNA replication licensing factor MCM3; ... 244 7e-63
UniRef50_Q236A7 Cluster: MCM2/3/5 family protein; n=1; Tetrahyme... 242 3e-62
UniRef50_Q5CTW9 Cluster: DNA replication licensing factor MCM4 l... 241 4e-62
UniRef50_Q9U1E0 Cluster: DNA replication licensing factor (CDC47... 238 4e-61
UniRef50_Q54CP4 Cluster: MCM family protein; n=1; Dictyostelium ... 237 6e-61
UniRef50_Q4WK28 Cluster: DNA replication licensing factor Mcm3, ... 237 6e-61
UniRef50_Q4DRN3 Cluster: Minichromosome maintenance (MCM) comple... 237 8e-61
UniRef50_A7D0S9 Cluster: MCM family protein; n=1; Halorubrum lac... 237 1e-60
UniRef50_Q9FL33 Cluster: DNA replication licensing factor MCM3 h... 237 1e-60
UniRef50_Q4QI01 Cluster: Minchromosome maintenance (MCM) complex... 236 1e-60
UniRef50_Q54VI9 Cluster: MCM family protein; n=1; Dictyostelium ... 236 2e-60
UniRef50_Q4QAP2 Cluster: Minchromosome maintenance (MCM) complex... 235 3e-60
UniRef50_A7ARB5 Cluster: ATP dependent DNA helicase, putative; n... 235 3e-60
UniRef50_Q7QSR9 Cluster: GLP_714_11088_8896; n=1; Giardia lambli... 235 5e-60
UniRef50_Q4Q8I2 Cluster: Minichromosome maintenance (MCM) comple... 235 5e-60
UniRef50_A5YS59 Cluster: MCM family protein; n=1; uncultured hal... 235 5e-60
UniRef50_A7PSR8 Cluster: Chromosome chr8 scaffold_29, whole geno... 233 1e-59
UniRef50_UPI00015B44D4 Cluster: PREDICTED: similar to MCM8 minic... 232 3e-59
UniRef50_A3M0C1 Cluster: DNA replication licensing factor, MCM2 ... 231 7e-59
UniRef50_Q7RJM3 Cluster: DNA replication licensing factor mcm7; ... 230 1e-58
UniRef50_Q5DVG0 Cluster: MCM/Rep protein; n=1; Sulfolobus neozea... 230 1e-58
UniRef50_Q6NRM6 Cluster: DNA replication licensing factor MCM9; ... 230 1e-58
UniRef50_Q8SS42 Cluster: DNA REPLICATION LICENSING FACTOR MCM2; ... 230 1e-58
UniRef50_Q6C0T3 Cluster: Similar to sp|P30666 Schizosaccharomyce... 229 2e-58
UniRef50_UPI0000E48FA2 Cluster: PREDICTED: similar to mini-chrom... 228 5e-58
UniRef50_A3ACA9 Cluster: Putative uncharacterized protein; n=2; ... 227 7e-58
UniRef50_A4RT02 Cluster: Replication origin activator MCM3, prob... 227 9e-58
UniRef50_Q8SQL8 Cluster: DNA REPLICATION LICENSING FACTOR OF THE... 227 1e-57
UniRef50_Q9NXL9 Cluster: DNA replication licensing factor MCM9; ... 226 2e-57
UniRef50_A0DH93 Cluster: Chromosome undetermined scaffold_50, wh... 226 2e-57
UniRef50_Q9UJA3 Cluster: DNA replication licensing factor MCM8; ... 225 4e-57
UniRef50_Q00Y49 Cluster: DNA replication licensing factor, MCM5 ... 224 6e-57
UniRef50_UPI0000DB74DE Cluster: PREDICTED: similar to minichromo... 223 1e-56
UniRef50_Q7R0J9 Cluster: GLP_154_53758_56232; n=1; Giardia lambl... 223 1e-56
UniRef50_Q4UHR0 Cluster: DNA replication licensing factor (MCM5 ... 223 1e-56
UniRef50_Q4UCK0 Cluster: DNA replication licensing factor (MCM7 ... 223 1e-56
UniRef50_A0BNH6 Cluster: Chromosome undetermined scaffold_118, w... 222 3e-56
UniRef50_Q5B060 Cluster: Putative uncharacterized protein; n=1; ... 219 3e-55
UniRef50_Q24849 Cluster: DNA replication licensing factor MCM3; ... 218 4e-55
UniRef50_Q01EH7 Cluster: Prolifera protein; n=1; Ostreococcus ta... 218 6e-55
UniRef50_Q54RN8 Cluster: MCM family protein; n=1; Dictyostelium ... 217 7e-55
UniRef50_Q74MT7 Cluster: NEQ282; n=1; Nanoarchaeum equitans|Rep:... 217 1e-54
UniRef50_Q9GR05 Cluster: DNA replication licensing factor MCM2; ... 213 2e-53
UniRef50_UPI000049A27A Cluster: DNA replication licensing factor... 211 6e-53
UniRef50_Q4RLI6 Cluster: Chromosome undetermined SCAF15020, whol... 211 6e-53
UniRef50_Q22GD2 Cluster: MCM2/3/5 family protein; n=1; Tetrahyme... 210 1e-52
UniRef50_A3B9P9 Cluster: Putative uncharacterized protein; n=4; ... 208 4e-52
UniRef50_Q4RF39 Cluster: Chromosome 14 SCAF15120, whole genome s... 207 8e-52
UniRef50_UPI000051A385 Cluster: PREDICTED: similar to DNA replic... 207 1e-51
UniRef50_Q7QPP1 Cluster: GLP_514_10128_7345; n=1; Giardia lambli... 206 1e-51
UniRef50_UPI0000D56719 Cluster: PREDICTED: similar to minichromo... 206 2e-51
UniRef50_UPI00004984D3 Cluster: DNA replication licensing factor... 206 2e-51
UniRef50_Q4Q3R6 Cluster: Minichromosome maintenance (MCM) comple... 206 2e-51
UniRef50_Q8SQX1 Cluster: DNA REPLICATION LICENSING FACTOR MCM4; ... 205 4e-51
UniRef50_Q0UXG2 Cluster: Putative uncharacterized protein; n=1; ... 205 4e-51
UniRef50_Q4N4V8 Cluster: DNA replication licensing factor MCM2, ... 204 6e-51
UniRef50_A0CQF3 Cluster: Chromosome undetermined scaffold_24, wh... 204 1e-50
UniRef50_A7AR97 Cluster: Minichromosome maintenance protein 3, p... 201 7e-50
UniRef50_Q7RI91 Cluster: Replication origin activator 2-related;... 200 9e-50
UniRef50_Q5CTT7 Cluster: DNA replication licensing factor MCM3 l... 200 1e-49
UniRef50_Q5V011 Cluster: MCM / cell division control protein 21;... 198 5e-49
UniRef50_Q17DG5 Cluster: DNA replication licensing factor MCM8; ... 198 6e-49
UniRef50_Q7R0Y4 Cluster: GLP_25_42162_38935; n=1; Giardia lambli... 197 1e-48
UniRef50_UPI0000D557CF Cluster: PREDICTED: similar to minichromo... 196 2e-48
UniRef50_Q7R0H3 Cluster: GLP_29_20689_22803; n=1; Giardia lambli... 194 1e-47
UniRef50_Q9UYR7 Cluster: MCM inteins containing helicase, minich... 193 1e-47
UniRef50_A3B4V6 Cluster: Putative uncharacterized protein; n=2; ... 192 2e-47
UniRef50_Q019K0 Cluster: DNA replication licensing factor, MCM5 ... 191 5e-47
UniRef50_Q16ZI3 Cluster: DNA replication licensing factor MCM1; ... 191 5e-47
UniRef50_Q4UAM8 Cluster: Cell division control protein, putative... 191 7e-47
UniRef50_Q495R6 Cluster: MCM8 protein; n=13; Eumetazoa|Rep: MCM8... 190 2e-46
UniRef50_Q3IML4 Cluster: ATP-dependent DNA helicase; n=1; Natron... 190 2e-46
UniRef50_Q54MD0 Cluster: MCM family protein; n=1; Dictyostelium ... 184 8e-45
UniRef50_Q235L3 Cluster: MCM2/3/5 family protein; n=1; Tetrahyme... 183 1e-44
UniRef50_Q5JGW1 Cluster: DNA replication licensing factor, MCM2/... 183 1e-44
UniRef50_Q2GYD6 Cluster: Putative uncharacterized protein; n=1; ... 182 3e-44
UniRef50_UPI00015B5C8D Cluster: PREDICTED: similar to mini-chrom... 182 3e-44
UniRef50_Q8TWR7 Cluster: Predicted ATPase involved in replicatio... 181 6e-44
UniRef50_Q8U3I4 Cluster: Cell division control protein 21; n=1; ... 181 8e-44
UniRef50_Q5UYX8 Cluster: Cell division control protein 21; n=1; ... 181 8e-44
UniRef50_Q8SRK9 Cluster: DNA REPLICATION LICENSING FACTOR OF THE... 178 5e-43
UniRef50_A0BKB5 Cluster: Chromosome undetermined scaffold_111, w... 177 1e-42
UniRef50_Q9HNA5 Cluster: MCM / cell division control protein 21;... 177 1e-42
UniRef50_A3DNW1 Cluster: MCM family protein; n=1; Staphylothermu... 174 9e-42
UniRef50_Q389T6 Cluster: Minichromosome maintenance (MCM) comple... 173 2e-41
UniRef50_Q4UH54 Cluster: DNA replication licensing factor Mcm2, ... 171 5e-41
UniRef50_Q58884 Cluster: Uncharacterized MCM-type protein MJ1489... 171 8e-41
UniRef50_A4HNF5 Cluster: DNA replication factor, putative; n=5; ... 170 1e-40
UniRef50_Q0W2N3 Cluster: Putative DNA replication licensing fact... 169 2e-40
UniRef50_A5K0L2 Cluster: DNA replication licensing factor MCM8, ... 165 5e-39
UniRef50_Q4QJG9 Cluster: DNA replication licensing factor, putat... 164 7e-39
UniRef50_Q38E36 Cluster: Minichromosome maintenance (MCM) comple... 163 2e-38
UniRef50_A3CUX8 Cluster: MCM family protein; n=1; Methanoculleus... 163 2e-38
UniRef50_A0ZYP8 Cluster: Putative uncharacterized protein; n=1; ... 156 3e-36
UniRef50_Q5JEJ0 Cluster: DNA replication licensing factor, MCM2/... 156 3e-36
UniRef50_Q57809 Cluster: Uncharacterized MCM-type protein MJ0363... 155 6e-36
UniRef50_A4R567 Cluster: Putative uncharacterized protein; n=1; ... 152 3e-35
UniRef50_A4IIB8 Cluster: MGC146393 protein; n=1; Xenopus tropica... 151 7e-35
UniRef50_A7D3N7 Cluster: MCM family protein; n=1; Halorubrum lac... 149 3e-34
UniRef50_Q58371 Cluster: Uncharacterized MCM-type protein MJ0961... 147 9e-34
UniRef50_A6UWD0 Cluster: MCM family protein; n=1; Methanococcus ... 145 4e-33
UniRef50_A4FXM1 Cluster: MCM family protein; n=3; Methanococcus|... 144 6e-33
UniRef50_Q4UHJ8 Cluster: Minichromosome maintenance (MCM), putat... 143 1e-32
UniRef50_Q0UY98 Cluster: Putative uncharacterized protein; n=1; ... 141 6e-32
UniRef50_Q4U9G0 Cluster: DNA replication protein (MCM homologue)... 136 2e-30
UniRef50_Q8I5T7 Cluster: Minichromosome maintenance protein, put... 130 1e-28
UniRef50_Q8I1S4 Cluster: DNA replication licensing factor, putat... 130 2e-28
UniRef50_A5K611 Cluster: DNA replication licensing factor, putat... 126 2e-27
UniRef50_Q7RKP3 Cluster: DNA replication licensing factor of the... 125 4e-27
UniRef50_Q4XQK3 Cluster: Minichromosome maintenance protein, put... 125 4e-27
UniRef50_Q5V814 Cluster: MCM / cell division control protein 21;... 122 5e-26
UniRef50_Q5JIT1 Cluster: DNA replication licensing factor, MCM2/... 121 7e-26
UniRef50_Q9VF30 Cluster: DNA replication licensing factor REC; n... 119 4e-25
UniRef50_Q7SHD5 Cluster: Putative uncharacterized protein NCU018... 117 1e-24
UniRef50_Q4XU98 Cluster: DNA replication licensing factor, putat... 115 4e-24
UniRef50_Q0UQC3 Cluster: Putative uncharacterized protein; n=1; ... 103 2e-20
UniRef50_A5DWW3 Cluster: Putative uncharacterized protein; n=1; ... 99 5e-19
UniRef50_Q8GSB2 Cluster: MCM5-like; n=19; Magnoliophyta|Rep: MCM... 92 5e-17
UniRef50_A7TAU8 Cluster: Predicted protein; n=1; Nematostella ve... 85 7e-15
UniRef50_Q4SLL7 Cluster: Chromosome 15 SCAF14556, whole genome s... 83 3e-14
UniRef50_Q8TWB5 Cluster: Predicted ATPase involved in replicatio... 78 8e-13
UniRef50_Q18E84 Cluster: ATP-dependent DNA helicase; n=1; Haloqu... 77 1e-12
UniRef50_Q4SRE5 Cluster: Chromosome undetermined SCAF14527, whol... 77 2e-12
UniRef50_A7QHD5 Cluster: Chromosome chr2 scaffold_97, whole geno... 77 2e-12
UniRef50_A5AUI5 Cluster: Putative uncharacterized protein; n=1; ... 76 4e-12
UniRef50_Q4SRE8 Cluster: Chromosome undetermined SCAF14527, whol... 74 1e-11
UniRef50_Q380P7 Cluster: ENSANGP00000029332; n=1; Anopheles gamb... 71 9e-11
UniRef50_Q45NK0 Cluster: Mini-chromosome maintenance protein; n=... 64 1e-08
UniRef50_Q2HFB8 Cluster: Putative uncharacterized protein; n=1; ... 62 4e-08
UniRef50_Q60275 Cluster: Uncharacterized MCM-type protein MJECL1... 59 5e-07
UniRef50_A2YAR1 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-05
UniRef50_A0DCN1 Cluster: Chromosome undetermined scaffold_45, wh... 54 2e-05
UniRef50_A7QHE6 Cluster: Chromosome chr2 scaffold_97, whole geno... 53 3e-05
UniRef50_Q3LW45 Cluster: Chromosome maintenance protein MCM4; n=... 51 1e-04
UniRef50_Q2GJW8 Cluster: Magnesium chelatase, subunit D/I family... 50 3e-04
UniRef50_Q01EK8 Cluster: Replication licensing factor MCM7 homol... 45 0.009
UniRef50_A5DWW4 Cluster: Putative uncharacterized protein; n=1; ... 45 0.009
UniRef50_Q4SGA7 Cluster: Chromosome 17 SCAF14597, whole genome s... 44 0.016
UniRef50_Q2FLV5 Cluster: Magnesium chelatase, ChlI subunit; n=1;... 44 0.016
UniRef50_A4M6H9 Cluster: Mg chelatase, subunit ChlI precursor; n... 44 0.021
UniRef50_A5DYY2 Cluster: Putative uncharacterized protein; n=1; ... 43 0.028
UniRef50_UPI000050C0BA Cluster: MCM complex subunit; AAA ATPase;... 43 0.037
UniRef50_Q897H3 Cluster: Regulatory protein moxR; n=1; Clostridi... 43 0.037
UniRef50_A7MLA0 Cluster: Putative uncharacterized protein; n=1; ... 43 0.037
UniRef50_A6C1F0 Cluster: Probable two-component response regulat... 43 0.037
UniRef50_Q81EV1 Cluster: MCM domain family protein; n=1; Bacillu... 42 0.049
UniRef50_A6EHC4 Cluster: Sigma-54-dependent transcriptional regu... 42 0.049
UniRef50_UPI0000E10DEA Cluster: competence protein ComM; n=1; al... 42 0.086
UniRef50_Q2RH79 Cluster: Sigma54 specific transcriptional regula... 41 0.11
UniRef50_Q2JEZ9 Cluster: AAA_3 ATPase associated with various ce... 41 0.11
UniRef50_A6LSN6 Cluster: Mg chelatase, subunit ChlI; n=1; Clostr... 40 0.20
UniRef50_Q4SVP9 Cluster: Chromosome undetermined SCAF13748, whol... 40 0.26
UniRef50_A6DKK7 Cluster: ATPase, AAA family protein; n=1; Lentis... 40 0.26
UniRef50_A1SGQ7 Cluster: ATPase associated with various cellular... 40 0.26
UniRef50_A2DZ79 Cluster: Putative uncharacterized protein; n=2; ... 40 0.26
UniRef50_A0RXY9 Cluster: Mg-chelatase subunit; n=1; Cenarchaeum ... 40 0.26
UniRef50_Q9WYY3 Cluster: ComM protein; n=3; Thermotogaceae|Rep: ... 40 0.35
UniRef50_Q5QZ88 Cluster: Competence related ATPase with chaperon... 40 0.35
UniRef50_Q0LJV9 Cluster: ATPase associated with various cellular... 40 0.35
UniRef50_Q4UM51 Cluster: Mg chelatase-related protein; n=18; Alp... 39 0.46
UniRef50_A7BDE3 Cluster: Putative uncharacterized protein; n=1; ... 39 0.46
UniRef50_A1VXR8 Cluster: Mg chelatase-related protein; n=10; Cam... 39 0.46
UniRef50_Q9U2P7 Cluster: Putative uncharacterized protein; n=1; ... 39 0.46
UniRef50_Q1DCC3 Cluster: Mg-chelatase subunits D/I family, ComM ... 39 0.61
UniRef50_P59402 Cluster: Anaerobic nitric oxide reductase transc... 39 0.61
UniRef50_P45049 Cluster: Competence protein comM; n=220; Bacteri... 39 0.61
UniRef50_Q1FF57 Cluster: Mg chelatase-related protein; n=5; Clos... 38 0.80
UniRef50_Q5V2T6 Cluster: Methanol dehydrogenase regulatory prote... 38 1.1
UniRef50_UPI000038E2E2 Cluster: hypothetical protein Faci_030013... 38 1.4
UniRef50_Q9AAN1 Cluster: MoxR protein; n=15; Bacteria|Rep: MoxR ... 38 1.4
UniRef50_Q6F1F2 Cluster: DNA repair DNA/RNA helicase; n=3; Entom... 38 1.4
UniRef50_Q6ABM1 Cluster: Magnesium-chelatase 67 kDa subunit; n=1... 38 1.4
UniRef50_A4V9E7 Cluster: Putative uncharacterized protein; n=6; ... 38 1.4
UniRef50_A1HMF5 Cluster: Radical SAM domain protein; n=1; Thermo... 38 1.4
UniRef50_Q5QZD8 Cluster: Response regulator containing CheY-like... 37 1.9
UniRef50_Q7X321 Cluster: Putative magnesium chelatase subunit I;... 37 1.9
UniRef50_A6TJT7 Cluster: Mg chelatase, subunit ChlI; n=2; Clostr... 37 1.9
UniRef50_A4V7B0 Cluster: Putative uncharacterized protein; n=1; ... 37 1.9
UniRef50_O34549 Cluster: Uncharacterized protein ylbO; n=3; Baci... 37 1.9
UniRef50_P59569 Cluster: tRNA modification GTPase trmE; n=1; Buc... 37 1.9
UniRef50_Q6C4A2 Cluster: Similarities with DEHA0F18689g Debaryom... 37 2.4
UniRef50_UPI00015BCE85 Cluster: UPI00015BCE85 related cluster; n... 36 3.2
UniRef50_Q1ARB9 Cluster: ATPase associated with various cellular... 36 3.2
UniRef50_UPI00006CA70D Cluster: hypothetical protein TTHERM_0084... 36 4.3
UniRef50_UPI000023E923 Cluster: hypothetical protein FG08961.1; ... 36 4.3
UniRef50_A6X3L7 Cluster: Two component, sigma54 specific, transc... 36 4.3
UniRef50_A1SLR4 Cluster: Mg chelatase, subunit ChlI; n=1; Nocard... 36 4.3
UniRef50_A4VB70 Cluster: Pol protein; n=13; Vanderwaltozyma poly... 36 4.3
UniRef50_Q4WVM7 Cluster: Serine/threonine-protein kinase tel1; n... 36 4.3
UniRef50_Q2AHB0 Cluster: Similar to Uncharacterized protein cons... 36 5.7
UniRef50_Q26BL4 Cluster: ATPase related to the helicase subunit ... 36 5.7
UniRef50_Q0C2X0 Cluster: ATPase, AAA family; n=2; Bacteria|Rep: ... 36 5.7
UniRef50_A6PSJ6 Cluster: Two component, sigma54 specific, transc... 36 5.7
UniRef50_P05407 Cluster: Nif-specific regulatory protein; n=30; ... 36 5.7
UniRef50_UPI00006CFCBC Cluster: Protein kinase domain containing... 35 7.5
UniRef50_Q7TFS6 Cluster: Rh55; n=2; Cercopithecine herpesvirus 8... 35 7.5
UniRef50_Q6A9R2 Cluster: Magnesium chelatase, subunit ChlI; n=3;... 35 7.5
UniRef50_Q1FHU7 Cluster: ATPase associated with various cellular... 35 7.5
UniRef50_A6LMX0 Cluster: Metallophosphoesterase; n=1; Thermosiph... 35 7.5
UniRef50_A5TVA5 Cluster: Possible ATP-binding protein; n=4; Fuso... 35 7.5
UniRef50_Q55FL8 Cluster: Putative uncharacterized protein; n=1; ... 35 7.5
UniRef50_Q16ZA4 Cluster: Putative uncharacterized protein; n=1; ... 35 7.5
UniRef50_UPI00006CF1DD Cluster: Helicase conserved C-terminal do... 35 9.9
UniRef50_UPI000065CBFD Cluster: Tyrosine-protein phosphatase non... 35 9.9
UniRef50_Q4T5T2 Cluster: Chromosome undetermined SCAF9119, whole... 35 9.9
UniRef50_Q9KQ67 Cluster: Sigma-54 dependent response regulator; ... 35 9.9
UniRef50_Q190P3 Cluster: Mg chelatase, subunit ChlI; n=2; Desulf... 35 9.9
UniRef50_Q0KHR4 Cluster: CG8923-PB, isoform B; n=10; Sophophora|... 35 9.9
>UniRef50_Q14566 Cluster: DNA replication licensing factor MCM6;
n=51; Eumetazoa|Rep: DNA replication licensing factor
MCM6 - Homo sapiens (Human)
Length = 821
Score = 975 bits (2414), Expect = 0.0
Identities = 500/820 (60%), Positives = 616/820 (75%), Gaps = 49/820 (5%)
Query: 12 QVKDEVGIRCQKLFQDFLEEFKE-DNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLA 70
+V+DEV +CQKLF DFLEEF+ D EIKY + A+EL++PE +TL VSF D+E++NQ L+
Sbjct: 17 EVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLS 76
Query: 71 TTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKI 130
TTI EE+YR+YP+L RA+ ++ E + KD YV+F D+PTRHK+RELT+++I
Sbjct: 77 TTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDF-----YVAFQDLPTRHKIRELTSSRI 131
Query: 131 GTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPTICRNPVCANRRRF 173
G L RISGQ+VRTHPVHPELV GTF YT P ICRNPVCANRRRF
Sbjct: 132 GLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRRRF 191
Query: 174 MLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVV 233
+LD +KS FVDFQK+RIQETQAELPRG IPRSLEVILRAEAVES QAGD+ DFTGTLIVV
Sbjct: 192 LLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVV 251
Query: 234 PDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFG 293
PDV LS PG+RAE +R + + EGI+GL+ALGVR+L Y+ FLAC V + RFG
Sbjct: 252 PDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFG 311
Query: 294 TAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLM 353
EL + T E ++ QMT KEW+KV+EMS+D+NLY+NL TSLFP+IHGN+EVKRGVLLM
Sbjct: 312 GKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLM 371
Query: 354 LFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTA 413
LFGGV KTT EGT+LRGDINVCIVGDPSTAKSQ LK V E +PRAVYTSGKASSAAGLTA
Sbjct: 372 LFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTA 431
Query: 414 AVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRA 473
AVVRDEES +FVIEAGALMLADNGVCCIDEFDKMD DQVAIHEAMEQQTIS+ KAGV+A
Sbjct: 432 AVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKA 491
Query: 474 TLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARK 533
TLNARTSILAAANPI G YDR+KSL+QN+ LS PIMSRFDLFFIL+DE +E+ DYAIAR+
Sbjct: 492 TLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARR 551
Query: 534 IVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYY-XXXXXXXXXXXX 592
IVDLH EES D VYS DD+ RY+ FAR FKP I++E+ +VE Y
Sbjct: 552 IVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTK 611
Query: 593 XXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEP 652
WRITVRQLESM+RL+E +A+MHC V P HV EA+RLLNKSIIRVE PD++LD++E
Sbjct: 612 SSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEE- 670
Query: 653 QCEPSMDVDQDEP--NGTAETPS------------NGDSAPKKKLALSFEEYKSLSNMLV 698
E M+VD+ NG A++P+ N +SAPK L L F EY +SN++V
Sbjct: 671 --EIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEYCRISNLIV 728
Query: 699 VYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLM 758
+++RK S + +S +V+WYL+++ + +I+SE+EL+ +K ++EKVI RL
Sbjct: 729 LHLRK-----VEEEEDESALKRSELVNWYLKEI--ESEIDSEEELINKKRIIEKVIHRLT 781
Query: 759 YHDQVIIPLSTTGLRGTQKSSEQDIEDDPLLVVHPNYVVD 798
++D V+I L+ GL+G+ + SE E+DP LVV+PNY+++
Sbjct: 782 HYDHVLIELTQAGLKGSTEGSE-SYEEDPYLVVNPNYLLE 820
>UniRef50_Q3E8H3 Cluster: Uncharacterized protein At5g44635.1; n=9;
Magnoliophyta|Rep: Uncharacterized protein At5g44635.1 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 831
Score = 641 bits (1583), Expect = 0.0
Identities = 356/828 (42%), Positives = 508/828 (61%), Gaps = 46/828 (5%)
Query: 13 VKDEVGIRCQKLFQDFLEEFKEDN---EIKYEKHAKELLKPELSTLEVSFDDVEKYNQNL 69
V DE I+ + +F +FL+ F+ D E+ YE + + E + + + F V +N L
Sbjct: 8 VMDEQAIQVENVFLEFLKSFRLDANKPELYYEAEIEAIRGGESTMMYIDFSHVMGFNDAL 67
Query: 70 ATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAK 129
I +EY R P+L A +++ + + + D +K+ VSF ++P ++RELTTA+
Sbjct: 68 QKAIADEYLRFEPYLRNACKRFVIEMNPSFISDDTPNKDINVSFYNLPFTKRLRELTTAE 127
Query: 130 IGTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPTICRNPVCANRRR 172
IG L+ ++G + RT V PEL+ GTF YT PTIC +P C NR R
Sbjct: 128 IGKLVSVTGVVTRTSEVRPELLYGTFKCLDCGSVIKNVEQQFKYTQPTICVSPTCLNRAR 187
Query: 173 FMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIV 232
+ L +S F D+Q++R+QET E+P G +PRSL+VILR E VE +AGD FTGT++V
Sbjct: 188 WALLRQESKFADWQRVRMQETSKEIPAGSLPRSLDVILRHEIVEQARAGDTVIFTGTVVV 247
Query: 233 VPDVGALSMPGSRAEI---TTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289
+PD+ AL+ PG RAE +++ K + G EG++GLKALGVR+L Y+ AF+A SVQ
Sbjct: 248 IPDISALAAPGERAECRRDSSQQKSSTAGH-EGVQGLKALGVRDLSYRLAFIANSVQIAD 306
Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349
T + + ED ++Q T +E D++ +M + +N L+ S+ P++ G+ ++KR
Sbjct: 307 GSRNTDMRNRQNDSNEDDQQQFTAEELDEIQQMRNTPDYFNKLVGSMAPTVFGHQDIKRA 366
Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409
VLLML GGV KTT EG LRGDINVCIVGDPS AKSQ LK + I PR+VYTSGK+SSAA
Sbjct: 367 VLLMLLGGVHKTTHEGINLRGDINVCIVGDPSCAKSQFLKYTAGIVPRSVYTSGKSSSAA 426
Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469
GLTA V ++ E+ +F IEAGALMLADNG+CCIDEFDKMD DQVAIHEAMEQQTIS+ KA
Sbjct: 427 GLTATVAKEPETGEFCIEAGALMLADNGICCIDEFDKMDIKDQVAIHEAMEQQTISITKA 486
Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529
G++ATLNARTSILAAANP+GGRYD++K L+ NV L P I+SRFDL +++ID+ E+ DY
Sbjct: 487 GIQATLNARTSILAAANPVGGRYDKSKPLKYNVNLPPAILSRFDLVYVMIDDPDEVTDYH 546
Query: 530 IARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVE-YYXXXXXXXX 588
IA IV +H E + ++ L RYIA+A++ KP ++ EA KLLVE Y
Sbjct: 547 IAHHIVRVHQKHEAALSPEFTTVQLKRYIAYAKTLKPKLSPEARKLLVESYVALRRGDTT 606
Query: 589 XXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLD 648
+R+TVRQLE+++RL+E +A+ H V P+HV A RLL S+I VE DI L
Sbjct: 607 PGTRVAYRMTVRQLEALIRLSEAIARSHLEILVKPSHVLLAVRLLKTSVISVESGDIDLS 666
Query: 649 E----------DEPQCEPSMDVDQDEPNGTAETPS--NGDSAPKKKLALSFEEYKSLSNM 696
E D E +D ++D+ NG AE S + A +KL +S EEY ++
Sbjct: 667 EYQDANGDNMDDTDDIENPVDGEEDQQNGAAEPASATADNGAAAQKLVISEEEYDRITQA 726
Query: 697 LVVYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDEL-LERKTLVEKVID 755
LV+ +R+ G+ + ++ W+++Q + + S++++ L+ K L +I+
Sbjct: 727 LVIRLRQHEETVNKDSSELPGIRQKELIRWFIDQQNEKKKYSSQEQVKLDIKKL-RAIIE 785
Query: 756 RLMYHDQVIIPLS-----TTGLRGTQKSSEQDIEDDPLLVVHPNYVVD 798
L+ + +I L+ T+K S Q D+ +L V PNYV++
Sbjct: 786 SLVCKEGHLIVLANEQEEAAEAEETKKKSSQ--RDERILAVAPNYVIE 831
>UniRef50_P49731 Cluster: DNA replication licensing factor mcm6;
n=4; Dikarya|Rep: DNA replication licensing factor mcm6
- Schizosaccharomyces pombe (Fission yeast)
Length = 892
Score = 609 bits (1505), Expect = e-173
Identities = 347/836 (41%), Positives = 502/836 (60%), Gaps = 63/836 (7%)
Query: 12 QVKDEVGIRCQKLFQDFLEEFKEDN------------EIKYEKHAKELLKPELSTLEVSF 59
+V D G ++ F++FL F +D E Y + L E+ T+ V +
Sbjct: 63 KVIDTTGESVREAFEEFLLSFSDDRVAGGDALPSASQEKYYVQQIHGLAMYEIHTVYVDY 122
Query: 60 DDVEKYNQNLATTIIEEYYRIYPFLNRAILNYI-----------LSLAETGMKKDLQ--D 106
+ YN LA I+E+YYR PFL RA+ I LS + + + D
Sbjct: 123 KHLTSYNDVLALAIVEQYYRFSPFLLRALQKLIEKFEPEYYRSSLSRENASLSPNFKASD 182
Query: 107 KECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF----------- 155
K ++F ++P R +R+L T +IG L I+G + RT V PEL QGTF
Sbjct: 183 KTFALAFYNLPFRSTIRDLRTDRIGRLTTITGTVTRTSEVRPELAQGTFICEECHTVVSN 242
Query: 156 ------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVI 209
YT PT C N +CAN+R + L+ +S F D+QK+RIQE E+P G +PR+L+VI
Sbjct: 243 VEQAFRYTEPTQCPNELCANKRSWRLNISQSSFQDWQKVRIQENSNEIPTGSMPRTLDVI 302
Query: 210 LRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKAL 269
LR + VE +AGD+ FTG LI VPDV L +PG + E ++ +G+ GLK+L
Sbjct: 303 LRGDIVERAKAGDKCAFTGILIAVPDVSQLGIPGVKPEAYRDSRNFGGRDADGVTGLKSL 362
Query: 270 GVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTT-----EDMRKQMTDKEWDKVYEMSR 324
GVR+L YK +FLAC VQ + D + ++ + ++ +E D + M
Sbjct: 363 GVRDLTYKLSFLACMVQPDDANDKSGADVRGDGSQGIEEQDEFLQSLSQEEIDDLRAMVH 422
Query: 325 DRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAK 384
++Y+ L SL PS++G+ +K+G+LL L GGV K T EG LRGD+N+CIVGDPST+K
Sbjct: 423 SDHIYSRLTNSLAPSVYGHEIIKKGILLQLMGGVHKLTPEGINLRGDLNICIVGDPSTSK 482
Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEF 444
SQ LK V PRA+YTSGKASSAAGLTAAVV+DEE+ DF IEAGALMLADNG+C IDEF
Sbjct: 483 SQFLKYVCNFLPRAIYTSGKASSAAGLTAAVVKDEETGDFTIEAGALMLADNGICAIDEF 542
Query: 445 DKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVAL 504
DKMD DQVAIHEAMEQQTIS+AKAG++ATLNARTSILAAANPIGGRY+R +L+ N+ +
Sbjct: 543 DKMDLSDQVAIHEAMEQQTISIAKAGIQATLNARTSILAAANPIGGRYNRKTTLRNNINM 602
Query: 505 SPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSF 564
S PIMSRFDLFF+++DE +E VD +A+ IVD+H ++++ +S + L RYI +AR+F
Sbjct: 603 SAPIMSRFDLFFVVLDECNESVDRHLAKHIVDIHRLRDDAMQPEFSTEQLQRYIRYARTF 662
Query: 565 KPVI-TEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTP 623
KP + TE +++ +Y +RITVRQLESM+RL+E +A+ +C +TP
Sbjct: 663 KPKLNTESCAEIVKKYKQLRMDDAQGAGKNSYRITVRQLESMIRLSEAIARANCVDDITP 722
Query: 624 AHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTAETPSNGDSAPKKKL 683
A V+EAY LL +SII VE+ DI ++ED+ + + + + + NG + S+ ++ K K+
Sbjct: 723 AFVNEAYSLLRQSIIHVERDDIEVEEDDAEAQELENDNTNTTNGN-DNVSSEEALQKPKV 781
Query: 684 ALSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDEL 743
+++++Y S+ N ++ +R+ G+ +V YLE + + Q +E+++
Sbjct: 782 KITYDKYVSIMNGILQVLRQRSTEGV------DGVPAGDLVQSYLE--LREDQFHTEEDI 833
Query: 744 LERKTLVEKVIDRLMYHDQVIIPLSTTGLRGTQKSSEQDIEDDPLLVVHPNYVVDA 799
+ LV KV+ RL+ H+ +I+ + T + E + + +HPN +DA
Sbjct: 834 IYEVGLVRKVLTRLV-HESIIMEIQNL----TDSAVRLPFE-ERVFSIHPNCDIDA 883
>UniRef50_Q239F7 Cluster: MCM2/3/5 family protein; n=1; Tetrahymena
thermophila SB210|Rep: MCM2/3/5 family protein -
Tetrahymena thermophila SB210
Length = 826
Score = 596 bits (1471), Expect = e-169
Identities = 323/787 (41%), Positives = 491/787 (62%), Gaps = 50/787 (6%)
Query: 25 FQDFLEEFK---EDNEIKYEKHAKELLKP-ELSTLEVSFDDVEKY--NQNLATTIIEEYY 78
F +FL F+ +IKY + LLK E +TL + F+ + + + +++ I+ +YY
Sbjct: 21 FLNFLNNFEVVENGKKIKYYREKALLLKIYEKNTLFIDFNHLLDFIDDNDISDVILNDYY 80
Query: 79 RIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISG 138
+I P L + + N+I SL T D Q+ Y+SF ++PT K+REL T +IG L I G
Sbjct: 81 KIEPHLRKIVSNFIFSLTNTN---DSQESY-YLSFYNLPTEKKIRELGTQEIGKLNSIKG 136
Query: 139 QIVRTHPVHPELVQGTF-----------------YTIPTICRNPVCANRRRFMLDADKSV 181
+ R+ V PEL+ GTF YT P IC NP C N ++ML SV
Sbjct: 137 LVTRSSEVRPELLYGTFICQLCNSEVRDIEQQFKYTEPKICSNPGCNNHTKWMLKPQSSV 196
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSM 241
F DFQK+R+QE ++P G +PRS++++ R E V++ + GD+ FTG LIVVPD+ AL+
Sbjct: 197 FSDFQKLRVQEESTDIPAGGMPRSIDIVCRGEVVDTAKPGDKCIFTGYLIVVPDIAALTK 256
Query: 242 PGSRAEITTRT---KLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGT---A 295
PG + E+ ++ ++ EG +GI GL LG R+L+Y+ FLA +++A RF
Sbjct: 257 PGEKTEMGIKSDAVRVKGEGNNDGITGLSQLGQRDLNYRLVFLAINIEAKKSRFNLWNQD 316
Query: 296 ELPTHDLTTEDMRKQM----TDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVL 351
E DLT E+ R+++ +++E + ++++SR N+Y L +SL P++HG+ EVK+G+L
Sbjct: 317 EEENQDLTEEEERQKIMENFSERELEDIFKISRSSNVYERLASSLCPTVHGHLEVKKGIL 376
Query: 352 LMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGL 411
LMLFGGV K T EG LRGDIN+C+VGDPSTAKSQ LK V+++ PR+VYTSGKAS++AGL
Sbjct: 377 LMLFGGVNKKTEEGINLRGDINICMVGDPSTAKSQFLKYVNKLIPRSVYTSGKASTSAGL 436
Query: 412 TAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGV 471
TA+V +D E+ + IEAGALML+D G+CCIDEFDKMD DQVAIHEAMEQQTIS++KAG+
Sbjct: 437 TASVSKDPETGENCIEAGALMLSDQGICCIDEFDKMDKRDQVAIHEAMEQQTISISKAGI 496
Query: 472 RATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIA 531
+ATLN+R SILAAANP+ GRYD++K L+ N+ +S PI+SRFDLFF+++DE +E D IA
Sbjct: 497 QATLNSRASILAAANPVFGRYDKSKGLKYNLDISAPILSRFDLFFVILDECNEQSDRMIA 556
Query: 532 RKIVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXX 591
+ IV++H + + + S +DL +YI FAR+ KP+ T EA L + Y
Sbjct: 557 QHIVNIHQSCGRNINPEISTEDLSKYIRFARTIKPIFTREAALELQKCYVKLRQNDSSSQ 616
Query: 592 XXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHL-DED 650
+RITVRQLES++RL+E +A++H VT V EA RLL+ SI+++E+ + + DE+
Sbjct: 617 NTSYRITVRQLESLIRLSEALARVHIQSEVTAEFVQEAARLLSNSILKIEKGQLDIQDEE 676
Query: 651 EPQCEPSMDVDQDEPNGTAETPSNGDSAPKK--KLALSFEEYKSLSNMLVVYMRKXXXXX 708
E + + + +Q + + KK K+++++EEY ++ +++ ++
Sbjct: 677 EQKIDLNQQKEQGQNIIQEDIEKKQQQQRKKEGKISITYEEYLNMRKIIIQTVKDLEIED 736
Query: 709 XXXXXX----------SSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLM 758
+G + ++ L+QL+ I++E++ + K + ++I +L+
Sbjct: 737 SLRVSTEGEDGMEVERQNGFEQRVIIEQILKQLLENDLIQTEEDATKLKKIYSQIIKKLV 796
Query: 759 YHDQVII 765
DQV+I
Sbjct: 797 DVDQVLI 803
>UniRef50_A3LR24 Cluster: DNA replication licensing factor, MCM6
component; n=4; Saccharomycetaceae|Rep: DNA replication
licensing factor, MCM6 component - Pichia stipitis
(Yeast)
Length = 949
Score = 585 bits (1444), Expect = e-165
Identities = 319/743 (42%), Positives = 455/743 (61%), Gaps = 50/743 (6%)
Query: 94 SLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQG 153
S + TG ++ +SF ++PT +++R++ TAKIG+L+ ISG + RT V PEL +
Sbjct: 196 SSSSTGAPGQSNERVFQISFFNLPTINRIRDIRTAKIGSLMSISGTVTRTSEVRPELFRA 255
Query: 154 TF-----------------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAE 196
+F YT PT C P C N+ F L+ KS F+D+Q++RIQE E
Sbjct: 256 SFTCDMCSAVIEGVEQVFKYTEPTSC--PSCENQSYFTLNVSKSQFIDWQRVRIQENSNE 313
Query: 197 LPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAE-ITTRTKLA 255
+P G +PR+L+VILR E VE + GD+ FTGT IV+PDV L +PG + + + +
Sbjct: 314 IPTGSMPRTLDVILRGETVERAKPGDKCKFTGTEIVIPDVSQLGLPGIKPQSVRDNRGVV 373
Query: 256 NEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGT--AELPTHDLTTEDMRKQ--- 310
+ I GLK+LGVR+L YK AF AC V ++ + + E + ++ + Q
Sbjct: 374 SSELSSAISGLKSLGVRDLTYKLAFHACHVSSLVNKSNSNGEEQDSTEVDYQGSNDQEIF 433
Query: 311 ---MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTT 367
++D E ++ EM +D ++YN L+ S+ P++ G+ VK+G+LL + GGV K TI+G
Sbjct: 434 LTSLSDSEVSQLKEMVKDEHVYNKLVQSIAPAVFGHEVVKKGILLQMLGGVHKQTIDGIN 493
Query: 368 LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIE 427
LRGDIN+CIVGDPST+KSQ LK V +PRA+YTSGKASSAAGLTAAVVRDEE+ ++ IE
Sbjct: 494 LRGDINICIVGDPSTSKSQFLKYVCGFSPRAIYTSGKASSAAGLTAAVVRDEETGEYTIE 553
Query: 428 AGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP 487
AGALMLADNG+C IDEFDKMD DQVAIHEAMEQQTIS+AKAG+ ATLNARTSILAAANP
Sbjct: 554 AGALMLADNGICAIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHATLNARTSILAAANP 613
Query: 488 IGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDC 547
IGGRY+R L+ N+ ++ PIMSRFDLFF+++D+ +E +D +A IVDLH ++E+ D
Sbjct: 614 IGGRYNRKLGLRSNLNMTAPIMSRFDLFFVILDDCNERIDTQLASHIVDLHMLRDEAIDP 673
Query: 548 VYSRDDLLRYIAFARSFKPVITEEAGKLLV-EYYXXXXXXXXXXXXXXWRITVRQLESMV 606
YS + L RYI +A++FKP +T+EA LV Y +RITVRQLESM+
Sbjct: 674 PYSAEQLARYIKYAKTFKPKMTKEARDFLVTRYKELRDDDAQGLGRSSYRITVRQLESMI 733
Query: 607 RLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPN 666
RL+E +A+ +C+ +TP+ V EAY LL +SIIRVE DI ++ED + D N
Sbjct: 734 RLSEAIARANCTEEITPSFVAEAYDLLKQSIIRVEMDDIEMEEDNEAVNDDDENDGSASN 793
Query: 667 GTAET--PSNGDSAP----------KKKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXXX 714
P D AP K+K+++ +++Y S+ N+LV
Sbjct: 794 DNDNNIEPLQEDGAPAQLQDTPRPKKEKVSIGYDKYVSMMNLLV------KRVSDDDSAG 847
Query: 715 SSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLRG 774
G+ +V+WYL Q + +I +E E + + + KV+ RL+ D++++ +
Sbjct: 848 GEGLGAEELVNWYLTQ--KENEIATEQEYYKERKMAYKVLKRLV-KDRILMSVINNESSL 904
Query: 775 TQKSSEQDIEDDPLLVVHPNYVV 797
+ + D + ++HPN +
Sbjct: 905 PDEEGASERVDKTIYILHPNCAI 927
>UniRef50_P53091 Cluster: DNA replication licensing factor MCM6; n=7;
Saccharomycetales|Rep: DNA replication licensing factor
MCM6 - Saccharomyces cerevisiae (Baker's yeast)
Length = 1017
Score = 583 bits (1439), Expect = e-165
Identities = 328/762 (43%), Positives = 469/762 (61%), Gaps = 74/762 (9%)
Query: 98 TGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF-- 155
T + ++ +SF ++PT H++R++ + KIG+L+ ISG + RT V PEL + +F
Sbjct: 252 TSTSPEQTERVFQISFFNLPTVHRIRDIRSEKIGSLLSISGTVTRTSEVRPELYKASFTC 311
Query: 156 ---------------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRG 200
YT PT C NP C NR + L+ +S F+D+QK+RIQE E+P G
Sbjct: 312 DMCRAIVDNVEQSFKYTEPTFCPNPSCENRAFWTLNVTRSRFLDWQKVRIQENANEIPTG 371
Query: 201 CIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTK---LANE 257
+PR+L+VILR ++VE + GDR FTG IVVPDV L +PG + T T+ E
Sbjct: 372 SMPRTLDVILRGDSVERAKPGDRCKFTGVEIVVPDVTQLGLPGVKPSSTLDTRGISKTTE 431
Query: 258 GQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGT-----------------AELPTH 300
G G+ GL++LGVR+L YK +FLAC V ++ G A L +
Sbjct: 432 GLNSGVTGLRSLGVRDLTYKISFLACHVISIGSNIGASSPDANSNNRETELQMAANLQAN 491
Query: 301 DLTTEDMRKQ------MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLML 354
++ ++ R Q ++ E +++ EM +D ++Y+ L+ S+ P++ G+ VK+G+LL +
Sbjct: 492 NVYQDNERDQEVFLNSLSSDEINELKEMVKDEHIYDKLVRSIAPAVFGHEAVKKGILLQM 551
Query: 355 FGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAA 414
GGV K+T+EG LRGDIN+C+VGDPST+KSQ LK V PR+VYTSGKASSAAGLTAA
Sbjct: 552 LGGVHKSTVEGIKLRGDINICVVGDPSTSKSQFLKYVVGFAPRSVYTSGKASSAAGLTAA 611
Query: 415 VVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRAT 474
VVRDEE D+ IEAGALMLADNG+CCIDEFDKMD DQVAIHEAMEQQTIS+AKAG+ AT
Sbjct: 612 VVRDEEGGDYTIEAGALMLADNGICCIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHAT 671
Query: 475 LNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKI 534
LNARTSILAAANP+GGRY+R SL+ N+ ++ PIMSRFDLFF+++D+ +E +D +A I
Sbjct: 672 LNARTSILAAANPVGGRYNRKLSLRGNLNMTAPIMSRFDLFFVILDDCNEKIDTELASHI 731
Query: 535 VDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVE-YYXXXXXXXXXXXXX 593
VDLH ++E+ + +S + L RYI +AR+FKP++T+EA LVE Y
Sbjct: 732 VDLHMKRDEAIEPPFSAEQLRRYIKYARTFKPILTKEARSYLVEKYKELRKDDAQGFSRS 791
Query: 594 XWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDED--- 650
+RITVRQLESM+RL+E +A+ +C +TP+ + EAY LL +SIIRV+ D+ +DE+
Sbjct: 792 SYRITVRQLESMIRLSEAIARANCVDEITPSFIAEAYDLLRQSIIRVDVDDVEMDEEFDN 851
Query: 651 -EPQCEPSMDVDQDEPNG------TAETPSN---GDS--------APKKKLALSFEEYKS 692
E Q + + D +G T+E P++ G S + KKK +++++Y S
Sbjct: 852 IESQSHAASGNNDDNDDGTGSGVITSEPPADIEEGQSEATARPGTSEKKKTTVTYDKYVS 911
Query: 693 LSNMLVVYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEK 752
+ NM+V RK + + +V WYL L + + S E E + L K
Sbjct: 912 MMNMIV---RKIAEVDREGAEELTAVD---IVDWYL--LQKENDLGSLAEYWEERRLAFK 963
Query: 753 VIDRLMYHDQVIIPLSTTGLRGTQKSSEQDIEDDPLLVVHPN 794
VI RL+ D++++ + T +E++ + + V+HPN
Sbjct: 964 VIKRLV-KDRILMEIHGTRHNLRDLENEENENNKTVYVIHPN 1004
Score = 36.3 bits (80), Expect = 3.2
Identities = 25/92 (27%), Positives = 47/92 (51%), Gaps = 7/92 (7%)
Query: 12 QVKDEVGIRCQKLFQDFLEEFK----EDNEIKYEKHAK-ELLKP-ELSTLEVSFDDVE-K 64
+V D G + ++ F+ FLE+F + E++ A+ E +K +L+T+ + + + +
Sbjct: 102 KVDDVTGEKVREAFEQFLEDFSVQSTDTGEVEKVYRAQIEFMKIYDLNTIYIDYQHLSMR 161
Query: 65 YNQNLATTIIEEYYRIYPFLNRAILNYILSLA 96
N LA I E+YYR FL + + + A
Sbjct: 162 ENGALAMAISEQYYRFLAFLQKGLRRVVRKYA 193
>UniRef50_Q1ZXM5 Cluster: MCM family protein; n=2; Dictyostelium
discoideum|Rep: MCM family protein - Dictyostelium
discoideum AX4
Length = 867
Score = 580 bits (1433), Expect = e-164
Identities = 329/805 (40%), Positives = 491/805 (60%), Gaps = 72/805 (8%)
Query: 40 YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETG 99
Y + + ++K + S+L + F +EK+++ L ++ EY+R+ P + + + +I +
Sbjct: 88 YRQQVERMIKNDKSSLYIDFLHLEKFDKGLGKALLMEYFRLEPAIRQGLSIFIQKYFPSF 147
Query: 100 MKKDLQDKECY-VSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF--- 155
M++ +++ + +V T +REL +++IG+L ISG + RT V PELV G+F
Sbjct: 148 MERVNKERIVLSICCYNVSTFVHIRELRSSRIGSLCSISGTVTRTSEVRPELVIGSFICK 207
Query: 156 --------------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGC 201
YT PT C NP+C+N+RR+ ++ ++S F D+QK+R+QE +E+P G
Sbjct: 208 DCNTSSLPIAQQFKYTEPTKCLNPLCSNQRRWKINLEESTFTDWQKVRVQENNSEIPGGS 267
Query: 202 IPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEI-------TTRTKL 254
+PRSLE+ILR ++VE+ +AGD F GT+ V+PDV +S+ G+ A+I T
Sbjct: 268 VPRSLEIILRGDSVETARAGDTCTFVGTMNVIPDVSKMSI-GNNAQIIKGVASSTKEGSN 326
Query: 255 AN-EGQMEGIKGLKALGVRELHYKTAFLACSVQA-------VSRRFGTAELPTHD----L 302
AN + G+ GLK LGVRE++Y+ F + SV++ ++R+ H +
Sbjct: 327 ANGKDDFGGVGGLKDLGVREMNYRVCFFSQSVRSNVSTLSSINRKESGDNHGGHSHSVGI 386
Query: 303 TTEDMRKQMTD--------KEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLML 354
ED+ + + KE D + +M + + +Y NL+ S+ PSI G+ E+KRGVLLML
Sbjct: 387 IDEDLEPESKESFLDSLPKKEKDSLKKMIKSKKIYQNLVNSICPSIFGHEEIKRGVLLML 446
Query: 355 FGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAA 414
FGGV K T E LRGDINVCIVGDPST+KS LK + PR VYTSGKASSAAGLTA
Sbjct: 447 FGGVHKKTPEKIRLRGDINVCIVGDPSTSKSTFLKYLVSFLPRTVYTSGKASSAAGLTAT 506
Query: 415 VVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRAT 474
VV+D+ES DF IEAGALMLADNG+CCIDEFDKM+PGDQVAIHEAMEQQTIS+AKAG+ A+
Sbjct: 507 VVKDQESGDFNIEAGALMLADNGICCIDEFDKMEPGDQVAIHEAMEQQTISIAKAGIHAS 566
Query: 475 LNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKI 534
LNARTSILAAANPIGGRYDR K+L+QN+ + P+MSRFDLFF+++DE + D+ IA I
Sbjct: 567 LNARTSILAAANPIGGRYDRNKTLKQNLNIGGPLMSRFDLFFVVLDECNPESDHRIAEHI 626
Query: 535 VDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXX- 593
V H +E++++ +S ++ YI + + P I +E+ +LLV +Y
Sbjct: 627 VLTHQKREKAFNAPFSATEIKNYIKYTKFICPTIPDESVQLLVGHYDRLRQMDTSGSKTP 686
Query: 594 XWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQ 653
+RITVRQLES+VRL+E +A++H V P +V+EA RLL KSI+ VE D+ L +D+
Sbjct: 687 AYRITVRQLESLVRLSESLARLHLDTKVLPKYVNEAARLLEKSIVHVETNDVILGDDDDD 746
Query: 654 CEPSMDVDQDEPNGTAETPSNGDSAPKKKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXX 713
+++ D D N E +G KL ++F +Y LS +LV+ +++
Sbjct: 747 LVKNVENDND--NHAEEDGDDGIG----KLTMNFSKYSQLSKLLVLQIKQ-------SGK 793
Query: 714 XSSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLR 773
SG+ + ++ WY++ + G I ++DE+ + + + VI++++ D ++ L
Sbjct: 794 EKSGIKQIDLIDWYIKDQLESG-IITDDEVTKETKITKMVINKMINKDNSLVVL------ 846
Query: 774 GTQKSSEQDIEDDPLLVVHPNYVVD 798
D +L++HPNY D
Sbjct: 847 -----VPNQYPDHRILIIHPNYSFD 866
>UniRef50_Q6CED4 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 921
Score = 567 bits (1399), Expect = e-160
Identities = 331/845 (39%), Positives = 490/845 (57%), Gaps = 77/845 (9%)
Query: 9 TQSQVKDEVGIRCQKLFQDFLE---------EFKEDNE------IKYEKHAKELLKPELS 53
T +V+D G + + LF++FLE E+ +D + Y + K L S
Sbjct: 75 TVPKVQDATGEKVRDLFEEFLETYVDGSNPEEYSDDEDGTAYDGRPYVRQIKGLRSFNKS 134
Query: 54 TLEVSFDDVEKYNQN-LATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDL-------- 104
++ V + + + LA I ++YYR PFL R + N I + +++ +
Sbjct: 135 SIFVDYRHMSETEDGILAQAISDQYYRFMPFLLRGLTNVIRKIEPVLLQQSVGFSEDGSS 194
Query: 105 ------------QDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQ 152
Q + + F ++P ++REL T KIG LI + G + RT V PEL
Sbjct: 195 TFGGSKSSSASDQPRHFQICFHNLPVVCRIRELKTDKIGCLISLGGTVTRTSEVRPELYL 254
Query: 153 GTF-----------------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQA 195
G F YT P+IC NP+C N++ + L D SVF+D+QK+R+QE
Sbjct: 255 GAFQCQECHTEVDGVEQVFKYTEPSICPNPMCGNKKMWKLLMDNSVFLDWQKVRVQENAH 314
Query: 196 ELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAE-ITTRTKL 254
E+P G +PR+++VILR E VE +AGD+ FTG +V+PDV L +PG + + +
Sbjct: 315 EIPAGSMPRTIDVILRGENVERARAGDQMIFTGAPVVIPDVTQLGLPGVKPRAVRDGGRE 374
Query: 255 ANEGQMEGIKGLKALGVRELHYKTAFLAC-----SVQAVSRRFGTAELPTHDLTTEDMRK 309
+ + + GL+ LG R+L Y+ +FLAC ++ S AE + E+ +
Sbjct: 375 TSAVESGAVTGLRELGARDLTYRISFLACYAAPANILDASANDNYAENAADE--QEEYIR 432
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
+ E +++ +M ++++ L+ S+ P+++G+ VK+G+LL L GGV K T +G LR
Sbjct: 433 SLKSAEVEQLRDMVHGQDIFRRLVRSIAPAVYGHETVKKGILLQLMGGVHKKTADGIRLR 492
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
GDIN+C+VGDPSTAKSQ LK V+ PR+VY SGKAS+AAGLTAAVV+DE+S +F IEAG
Sbjct: 493 GDINICLVGDPSTAKSQFLKYVTSFLPRSVYASGKASTAAGLTAAVVKDEDSGEFTIEAG 552
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489
ALMLADNG+C IDEFDKMD DQVAIHEAMEQQTIS+AKAG+ ATLNARTSILAAANP
Sbjct: 553 ALMLADNGICAIDEFDKMDLADQVAIHEAMEQQTISIAKAGINATLNARTSILAAANPAK 612
Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVY 549
GRYDR L+ NV +S PIMSRFDLFF+++DE +E D A+A +VDLH + +E+ D +
Sbjct: 613 GRYDRRLGLRANVQMSAPIMSRFDLFFVILDECNEATDTALASHVVDLHMHTDEAIDPPF 672
Query: 550 SRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLA 609
S + L R+I +AR+FKP++T EA +LV+ Y +RITVRQLESM+RL+
Sbjct: 673 STEQLQRFIKYARTFKPMLTPEARAVLVQQYQQLRADDATGAGNSYRITVRQLESMIRLS 732
Query: 610 EGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTA 669
E +A+ +CS ++PA VHEA +LL +II VE+ D+ LDE+ E ++D +D +
Sbjct: 733 EAIARANCSTIISPAFVHEAAKLLRDTIILVEREDVLLDEE----EDTVDAAEDAVDEAM 788
Query: 670 ETPSNGDSAPKKKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHKSAVVSWYLE 729
E + P+ + ++ ++Y + NM+V + + GM A++ + LE
Sbjct: 789 EATQLANHTPRDQ--ITHQQYTHMVNMIVSKLSENYTDDADASRI--GMSLDALLEFVLE 844
Query: 730 QLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLRGTQKSSEQDIEDDPLL 789
Q + ++ ED +E T + K + + M + +++ +RG E + L
Sbjct: 845 Q-YEEDMVDEED--VENHTRLTKKVIKKMKKNNLLMT-----VRGNLDDLEAPGDGTELY 896
Query: 790 VVHPN 794
V+HPN
Sbjct: 897 VIHPN 901
>UniRef50_A0EIN0 Cluster: Chromosome undetermined scaffold_99, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_99,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 805
Score = 561 bits (1384), Expect = e-158
Identities = 313/779 (40%), Positives = 465/779 (59%), Gaps = 39/779 (5%)
Query: 22 QKLFQDFLEEFKEDNE------IKYEKHAKELLKPELSTLEVSFDDVEKYN--QNLATTI 73
Q F FL+EF+ N Y + A+ + + +TL + F + + Q+L+ +
Sbjct: 10 QNRFLHFLQEFRTINPQTGESFYYYHEEARIMRDNDRTTLNLDFTHITQTEGYQDLSIIM 69
Query: 74 IEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTL 133
++Y+ P RAI ++ + ++ + K +++ ++ K+R+L KIG L
Sbjct: 70 QTDFYQFEPSFRRAIQEFMF-IQHQDVEDQCKQKLYFLAVSNLAATEKIRDLRANKIGKL 128
Query: 134 IRISGQIVRTHPVHPELVQGTF-----------------YTIPTICRNPVCANRRRFMLD 176
G + RT+ V PEL+ G F +T P C N C N+ R+ ++
Sbjct: 129 SSFIGTVTRTYEVRPELLSGQFTCQMCDRIIDNVEQQFKFTEPKKCPNTKCDNKSRWTIN 188
Query: 177 ADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDV 236
+KS F DFQK+R+QE ++P G +PRS++VIL E ++ + GD+ F G L V+PDV
Sbjct: 189 LNKSQFTDFQKVRVQEDSKDIPAGSMPRSIDVILHNEKCDAAKPGDKCTFNGYLTVIPDV 248
Query: 237 GALSMPGSRAEITTRTKLANE-GQ-MEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGT 294
+L PG ++ +TT+ + N+ GQ +GI GLK LGV++L YK F+ACSV+ + RF
Sbjct: 249 FSLGKPGLKSSMTTQNQGNNQRGQTQDGITGLKQLGVKDLCYKFVFIACSVETNNNRFNL 308
Query: 295 AELP------THDLTTEDMRK--QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEV 346
+ T L+ +D ++ Q D E ++ EM + +L+ NL S+ P++ G ++
Sbjct: 309 QKQQIDDKEYTESLSDQDAKRGQQFDDYEKQEILEMKKQPDLFKNLANSIAPAVQGYEDI 368
Query: 347 KRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKAS 406
K+G+LLML GGV KTT EG +RGDINVCIVGDPSTAKSQ LK + PR+VYTSGKAS
Sbjct: 369 KKGILLMLMGGVYKTTKEGVHIRGDINVCIVGDPSTAKSQFLKFTCNLLPRSVYTSGKAS 428
Query: 407 SAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISL 466
SAAGLTA+V RD E+ +F IEAGALMLADNG+CCIDEFDKMD DQVAIHEAMEQQTIS+
Sbjct: 429 SAAGLTASVHRDIENGEFCIEAGALMLADNGICCIDEFDKMDSKDQVAIHEAMEQQTISI 488
Query: 467 AKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMV 526
AKAG++ATLNARTSILAAANPI GRYDR+K+L+ NV ++ PIMSRFDLFFI+ D V
Sbjct: 489 AKAGIQATLNARTSILAAANPIFGRYDRSKTLKFNVNMTQPIMSRFDLFFIITDACRPFV 548
Query: 527 DYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXX 586
D IA IV LH +E + + +S+D L +YI +AR+FKP++T E+ + L E Y
Sbjct: 549 DEQIATHIVRLHSQQEGAIEPRFSQDQLRKYIRYARTFKPILTHESAQYLKEAYIRLREN 608
Query: 587 XXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIH 646
+RITVRQLES++RL+E +A++ C + ++V EA +LL +SI++V++
Sbjct: 609 DQTSQRTSYRITVRQLESLIRLSEALARVQCDDFIKISYVQEAEKLLGQSILQVDETPKF 668
Query: 647 LDEDEPQCEPSMDVDQDEPNGTAETPSNGDSAPKKKLALSFEEYKSLSNMLVVYMRKXXX 706
+D+ E Q +P + +K+ L+ +EY + L +M +
Sbjct: 669 IDDLEEQ-QPIQTRAMGIIEEELQQKERERRRQGQKIQLAQDEYLDIVRALTSFMIQKER 727
Query: 707 XXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVII 765
+ G+ + WY+ + QIE E+E+ + + LV VI +++ +++++
Sbjct: 728 EMQEEITEAKGVKWEDLAEWYITNKL--DQIEHEEEVHQYERLVGAVIRQMINKEKILV 784
>UniRef50_Q2TWS7 Cluster: DNA replication licensing factor; n=14;
Ascomycota|Rep: DNA replication licensing factor -
Aspergillus oryzae
Length = 970
Score = 554 bits (1368), Expect = e-156
Identities = 322/748 (43%), Positives = 451/748 (60%), Gaps = 66/748 (8%)
Query: 106 DKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF---------- 155
DK ++F ++P ++R+L T++IG L+ ISG + RT + PEL GTF
Sbjct: 223 DKLFSLAFYNLPLVSRLRQLRTSQIGKLLSISGTVTRTSEIRPELSLGTFICENCKTVCP 282
Query: 156 -------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEV 208
YT P+ C N C NR + LD KS FVD+QK+++QE+ E+P G +PR+++V
Sbjct: 283 DVEQTFKYTEPSECPNQSCGNRSGWRLDIGKSTFVDWQKVKLQESSHEIPTGSMPRTMDV 342
Query: 209 ILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG--IKGL 266
ILR E V+ +AG+R FTGTLIVVPDV L +PG R E G + G + GL
Sbjct: 343 ILRGEMVDRAKAGERCIFTGTLIVVPDVSQLGLPGVRPEAVRDDSAFRSGDVGGGGLTGL 402
Query: 267 KALGVRELHYKTAFLACSV------------QAVSRRFGTAELPTHDLT----TEDMRKQ 310
KALG R+L Y+ AFLAC V Q ++ + + LT ED ++
Sbjct: 403 KALGARDLTYRLAFLACMVTPDTTTPGQQTNQQLNGQSNNILASLNQLTEPEDNEDKAQE 462
Query: 311 -----MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTI-E 364
+T E + + + +Y+ L+ S+ P I+G+ ++K+G+LL L GGV+K T E
Sbjct: 463 AFLHTLTPYEVEDLKGLVHSDYIYSRLVDSIAPMIYGHRQIKKGLLLQLIGGVSKNTAQE 522
Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDF 424
LRGDINVCIVGDPST+KSQ LK + + PRAVYTSGKASSAAGLTA+VV+D E+ +F
Sbjct: 523 NMQLRGDINVCIVGDPSTSKSQFLKYICSLHPRAVYTSGKASSAAGLTASVVKDAETGEF 582
Query: 425 VIEAGALMLADNG-VCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILA 483
IEAGALMLA+ G +C IDEFDKMD DQVAIHEAMEQQTIS+AKAG+ TLNAR SILA
Sbjct: 583 TIEAGALMLANGGGICAIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHTTLNARASILA 642
Query: 484 AANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE 543
AANPIGGRY+ +L+ N+ S PIMSRFDLFF++ DE +E VD +A IV++H N++E
Sbjct: 643 AANPIGGRYNPKATLRANLNFSAPIMSRFDLFFVIRDEPNETVDRNLADHIVNVHMNRDE 702
Query: 544 SYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYY--XXXXXXXXXXXXXXWRITVRQ 601
+ S + L RYI FAR+F+PV T+EA LLVE Y +RITVRQ
Sbjct: 703 AVQPELSTEQLQRYIRFARTFRPVFTDEAKALLVEKYKELRSNDSQGGNGRSSYRITVRQ 762
Query: 602 LESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVD 661
LES+VRL+E VAK +C + P V EAY LL +SI+ VE+ D+ +D+DE + + D
Sbjct: 763 LESLVRLSEAVAKANCVEEIVPRFVQEAYDLLRQSIVTVEKDDVEVDDDE-ELANAAGHD 821
Query: 662 QDEPNGTAETPSNGDS----------APKK-KLALSFEEYKSLSNMLVVYMRKXXXXXXX 710
+D G E GDS AP + + ++F++Y + N++V + +
Sbjct: 822 EDHEMGDGERDREGDSPMREDVEEQPAPSRTRTKITFDKYMKILNLVVRRVNE------D 875
Query: 711 XXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTT 770
G+ + ++ WYLEQ+ + ++++E++L ++L KV+ R M D +++P+
Sbjct: 876 ESTSGEGVEEEDLIVWYLEQI--ESELDNEEDLQRERSLAVKVLKR-MVKDNILMPIRGE 932
Query: 771 GLRGTQKSSEQDIEDDPLLVVHPNYVVD 798
GL +Q+ + V+HPN VD
Sbjct: 933 GLVDA-ADGDQETSHRTVYVLHPNCAVD 959
Score = 38.7 bits (86), Expect = 0.61
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 14/92 (15%)
Query: 15 DEVGIRCQKLFQDFLEEFKED---------NEIKYEKH----AKELLKPELSTLEVSFDD 61
D G + Q+ F++ LE ++E+ +EI +K+ + K LSTL V F
Sbjct: 78 DVAGEKVQQAFEELLETYREEPTWSAPPPSSEILSDKYYIAQIHGMNKHSLSTLYVDFTH 137
Query: 62 VEKYNQN-LATTIIEEYYRIYPFLNRAILNYI 92
+ + LA I+ ++YR +PFL +A+ N I
Sbjct: 138 LTSLDSPILADAIVNQFYRFHPFLTKALHNLI 169
>UniRef50_Q01GI0 Cluster: Mini-chromosome maintenance protein MCM6;
n=2; Ostreococcus|Rep: Mini-chromosome maintenance
protein MCM6 - Ostreococcus tauri
Length = 873
Score = 552 bits (1362), Expect = e-155
Identities = 322/817 (39%), Positives = 470/817 (57%), Gaps = 62/817 (7%)
Query: 28 FLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIE-EYYRIYPFLNR 86
F +E + + Y + +TL V F+ + + + LA ++ +Y PFL+
Sbjct: 42 FRDEARRARRLVYVEQLFSDAMENKTTLTVDFEHLNQKDSELAVEAVQANFYMYQPFLHD 101
Query: 87 AILNYILS-----LAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIV 141
A+ ++ + G + ++KE +V FV++P ++R L IG L SG +
Sbjct: 102 AVKVFVRQHRPELVRYAGGVEKSREKEFWVKFVNLPRVERLRSLRANNIGQLSSFSGTVT 161
Query: 142 RTHPVHPELVQGTF-----------------YTIPTICRNPVCANRRRFMLDADKSVFVD 184
RT V PEL+ G F YT P+IC C NR ++ L+ + FVD
Sbjct: 162 RTSEVRPELLLGCFKCGECNTLVPNVEQQCRYTEPSICLLETCGNRTKWTLEREGCKFVD 221
Query: 185 FQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGS 244
+Q++R+QE E+P G +PRS++VILR E VE +AGD+ FTGTL+VVP+V +M G
Sbjct: 222 WQRVRVQENADEVPAGSLPRSMDVILRHEIVEEARAGDKAIFTGTLLVVPEVAPKNMAGD 281
Query: 245 RAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTH-DLT 303
R E+ + K G+ +G+ GL+ G REL Y+ F+A SV + G ++ D
Sbjct: 282 RTELQSSVK----GRSDGVSGLRQFGCRELFYRMVFVAQSVVNTADPGGGGDVDIRGDDE 337
Query: 304 TEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTI 363
+ + + ++ +E ++ +M++D +LY+ + S+ P++HG+ ++KR + LMLFGGV K+T
Sbjct: 338 EKKVVETLSSQERREITQMAQDPHLYDKFVKSIAPTVHGHGDIKRAITLMLFGGVHKSTG 397
Query: 364 EGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD 423
LRGDINV IVGDPS AKSQ LK VS PRAVYTSGK+SSAAGLTA V +D E+ +
Sbjct: 398 AKQGLRGDINVLIVGDPSCAKSQFLKYVSSFLPRAVYTSGKSSSAAGLTATVAKDVETGE 457
Query: 424 FVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILA 483
+ IEAGALMLADNG+CCIDEFDKMD DQVAIHEAMEQQTIS+AKAGV+A+L ARTSILA
Sbjct: 458 YCIEAGALMLADNGICCIDEFDKMDVKDQVAIHEAMEQQTISIAKAGVQASLQARTSILA 517
Query: 484 AANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE 543
AANP GGRYDR+K L+ N+AL P I+SRFDL ++IDE E DY +AR IV LH +E
Sbjct: 518 AANPNGGRYDRSKKLRHNLALPPAILSRFDLVHVMIDEPDEFHDYTLARHIVSLHQKRET 577
Query: 544 SYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVE-YYXXXXXXXXXXXXXXWRITVRQL 602
+ + Y+ + L RYI +AR+ KP +T EA K +V Y +RITVRQL
Sbjct: 578 AVNVDYTLEQLQRYIRYARTIKPQMTPEAQKEIVNAYVKLRTGDSQPGTQTAYRITVRQL 637
Query: 603 ESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCE------- 655
E++VRL+E +A++HC V P HV EA RLL++SII +E D+ LD D+ + E
Sbjct: 638 EAIVRLSEALARLHCRAEVHPKHVREARRLLSESIIALEAGDVVLDADDVELENDESRPI 697
Query: 656 ------PSMDVDQDEPNGTAETPSN----------------GDSAPKKKLALSFEEYKSL 693
S+ + E A+ +N G KKK +S E++ +
Sbjct: 698 LPEQVLASLHAKRQEQEREAKEQANKAANASEDDAMAPAEPGRVPEKKKTKVSAEKFNQV 757
Query: 694 SNMLVVYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKV 753
++L+ +MR+ +G+ + ++SWY+++ V + ++LL LV +
Sbjct: 758 KHILLRHMRE--REMELEGGEDTGIVQKDLISWYIDEQVVPSGVSDPEQLLAEYKLVRNI 815
Query: 754 IDRLMYHDQVIIPLSTTGLRGTQKSSEQDIEDDPLLV 790
I+ L+ + + + +E D E DP +V
Sbjct: 816 INHLVNRESTLNVIQEA--EPAPMLTEGDEELDPTVV 850
>UniRef50_A6QU77 Cluster: Putative uncharacterized protein; n=1;
Ajellomyces capsulatus NAm1|Rep: Putative
uncharacterized protein - Ajellomyces capsulatus NAm1
Length = 925
Score = 516 bits (1272), Expect = e-144
Identities = 305/738 (41%), Positives = 440/738 (59%), Gaps = 77/738 (10%)
Query: 106 DKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNP 165
DK ++F ++P ++R+L TA+IG L+ ISG + RT V PEL
Sbjct: 218 DKVFSLAFYNLPLVSRLRQLRTAQIGKLLSISGTVTRTSEVRPELA-------------- 263
Query: 166 VCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYD 225
LD +S F+D+QK+++QE+ E+P G +PR++++ILR E V+ +AG+R
Sbjct: 264 ---------LDIRQSTFIDWQKVKLQESSHEIPTGSMPRTMDIILRGEMVDRAKAGERCI 314
Query: 226 FTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQM--EGIKGLKALGVRELHYKTAFLAC 283
FTGTLIVVPDV L +PG R E T + G+ GLK+LGVR+L Y+ AF+AC
Sbjct: 315 FTGTLIVVPDVSQLGLPGVRPEATRDNGNFRGSDVGGNGVSGLKSLGVRDLTYRLAFVAC 374
Query: 284 SV--------QAVSRRFG------------TAELPTHDLTTED-MRKQMTDKEWDKVYEM 322
V +A S++ T +L T++ +D + + +T E + +
Sbjct: 375 MVTPDLTTPGRASSQQLNGQSQNILASLNQTDQLETYEDEAQDHLLQTLTPYEVQDLKNL 434
Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTT-IEGTTLRGDINVCIVGDPS 381
+Y+ L+ S+ P I+G+ +K+G+LL L GGV+KTT E +RGDIN+CIVGDPS
Sbjct: 435 VHSEYIYSRLVDSIAPMIYGHRAIKKGLLLQLIGGVSKTTQQENMQIRGDINICIVGDPS 494
Query: 382 TAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLAD-NGVCC 440
T+KSQ LK + + PRAVYTSGKASSAAGLTA+VV+D E+ +F IEAGALMLA+ G+C
Sbjct: 495 TSKSQFLKYICSLNPRAVYTSGKASSAAGLTASVVKDPETGEFTIEAGALMLANGGGICA 554
Query: 441 IDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQ 500
IDEFDKMD DQVAIHEAMEQQTIS+AKAG+ TLNAR SILAAANPIGGRY+ +L+
Sbjct: 555 IDEFDKMDISDQVAIHEAMEQQTISIAKAGIHTTLNARASILAAANPIGGRYNPKATLRA 614
Query: 501 NVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAF 560
N+ S PIMSRFDLFF++ DE +E VD +A IV++H N++++ + + + L RYI F
Sbjct: 615 NLNFSAPIMSRFDLFFVIRDEPNEAVDRNLAEHIVNVHMNRDDAVEPDLTTEQLQRYIRF 674
Query: 561 ARSFKPVITEEAGKLLVEYY--XXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCS 618
AR+F+PV TEEA +LLVE Y +RITVRQLES++RL+E VAK +C
Sbjct: 675 ARTFRPVFTEEAKELLVEKYKELRANDAQGGLGRSSYRITVRQLESLIRLSEAVAKANCV 734
Query: 619 GHVTPAHVHEAYRLLNKSIIRVEQPDIHLDE---DE--------PQCEPSMDVDQDEPNG 667
+ P+ V EA+ LL +SI+ VE+ D+ +D+ D+ P D D D P
Sbjct: 735 EEIVPSFVKEAFDLLRQSIVTVEKDDVEVDDGTGDQNADSASGIRDAAPHQDRDGDSPMR 794
Query: 668 TAE------TPSNGDSAPK-KKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHK 720
T + P P+ +K +++++Y + N+LV G+ +
Sbjct: 795 TGDDDDHVNAPHVTTQQPQTQKTKITYDKYMRILNILV------RRVNDDEANAGDGVEQ 848
Query: 721 SAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLRGTQKSSE 780
++ WYLEQ+ + ++ SE+E+ ++L KV+ R M D +++ + GL + +
Sbjct: 849 EDLIVWYLEQI--ESELNSEEEMEAERSLAVKVLKR-MVKDNILMHIRGEGLVESDDQQQ 905
Query: 781 QDIEDDPLLVVHPNYVVD 798
Q E + V+HPN V+
Sbjct: 906 QQQEQRVVYVLHPNCAVE 923
>UniRef50_Q5BGV2 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 915
Score = 513 bits (1266), Expect = e-144
Identities = 329/851 (38%), Positives = 470/851 (55%), Gaps = 80/851 (9%)
Query: 13 VKDEVGIRCQKLFQDFLEEFKEDNEIK---------------YEKHAKELLKPELSTLEV 57
V D G + Q+ F++ LE ++E+ K Y + K ELSTL V
Sbjct: 78 VVDLAGEKVQQAFEELLENYQEEAPPKSSHTPQSSAPMTNKYYIAQIHGMAKWELSTLYV 137
Query: 58 SFDDVEKY-NQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDV 116
F + N LA I +YYR PFL +A+ N I Q S
Sbjct: 138 DFTHLTSLDNPILADAIANQYYRFQPFLVKALHNLIAKYEPEYFVSHRQATSSVSS--QA 195
Query: 117 PTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICR------------- 163
T + A L R + R H +L FY +P + R
Sbjct: 196 GTSLMAGNSSVADDPKLDRTIREKTR-HQQTDKLFALAFYNLPLVSRLRQLRTSQIGKLL 254
Query: 164 --NPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAG 221
+ + F+ +QK+++QE+ E+P G +PR+++VILR E V+ V+AG
Sbjct: 255 SVSGTVTRTSEIRPELSLGTFIYWQKVKLQESSHEIPTGSMPRTMDVILRGEMVDRVKAG 314
Query: 222 DRYDFTGTLIVVPDVGALSMPGSRAEITTRTK--LANEGQMEGIKGLKALGVRELHYKTA 279
+R FTGTLIV+PDV L +PG R E +N+ G+ GLKALGVR+L Y+ A
Sbjct: 315 ERCIFTGTLIVIPDVSQLGLPGVRPEAVRDNSGFRSNDVGGGGVSGLKALGVRDLTYRLA 374
Query: 280 FLACSV------------QAVS----RRFGTAEL-----PTHDLTTEDMRKQMTDKEWDK 318
FL C V Q +S R G+ P D E + ++ E +
Sbjct: 375 FLTCMVTPDTTTPGQQSNQQLSGQSNRILGSLNQNPDPEPDDDKAQEAFLQSLSPAEVED 434
Query: 319 VYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTI-EGTTLRGDINVCIV 377
+ M +Y+ L+ S+ P I+G+ ++K+G+LL L GGVAK+T E LRGDIN+CIV
Sbjct: 435 LKTMVHSEYIYSRLVDSMAPMIYGHRQIKKGLLLQLVGGVAKSTEQESLQLRGDINICIV 494
Query: 378 GDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNG 437
GDPST+KSQ LK + + PRAVYTSGKASSAAGLTA VV+D E+ +F IEAGALMLA+ G
Sbjct: 495 GDPSTSKSQFLKYICSLHPRAVYTSGKASSAAGLTAKVVKDAETGEFTIEAGALMLANGG 554
Query: 438 -VCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAK 496
+C IDEFDKMD DQVAIHEAMEQQTIS+AKAG+ TLNAR SILAAANPIGGRY+
Sbjct: 555 GICAIDEFDKMDISDQVAIHEAMEQQTISIAKAGIHTTLNARASILAAANPIGGRYNPKT 614
Query: 497 SLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLR 556
+L+ N+ S PIMSRFDLFF++ DE +E VD +A IV++H N++ + + +S + L R
Sbjct: 615 TLRGNLNFSAPIMSRFDLFFVIRDEPNEDVDRNLADHIVNVHMNRDAAVEPEFSTEQLQR 674
Query: 557 YIAFARSFKPVITEEAGKLLVEYY--XXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAK 614
YI FAR+F+PV EEA +LVE Y +RITVRQLES++RL+E +AK
Sbjct: 675 YIRFARTFRPVFREEAKAVLVEKYKELRANDAQGGMGRSSYRITVRQLESLIRLSEAIAK 734
Query: 615 MHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQC---EPSMDVDQDEPNGTAET 671
++C + P V EAY LL +SI+ VE+ D+ +++DE E D D+D + E
Sbjct: 735 VNCVEEIVPKFVREAYDLLRQSIVTVEKDDVEVEDDEGAANADEDMPDRDRDGDSPMREE 794
Query: 672 PSNGDSA----PKKKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHKSAVVSWY 727
P + +A P+ K +++++Y + N++V +R+ G+ + ++ WY
Sbjct: 795 PQSAAAAEPVEPRAKTKITYDKYMKILNLVVRRIRE------DEAQAGEGVEQEDLLVWY 848
Query: 728 LEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLRGTQKSSEQDIEDDP 787
LEQ+ + ++ +E++L ++L KV+ R M D +++P+ GL ++SE D
Sbjct: 849 LEQI--EAELNNEEDLQRERSLAVKVLKR-MVKDNILMPIRGEGL--VDEASEVQ-TDRT 902
Query: 788 LLVVHPNYVVD 798
+ V+HPN +D
Sbjct: 903 IYVLHPNCAID 913
>UniRef50_A2DDL4 Cluster: MCM2/3/5 family protein; n=1; Trichomonas
vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas
vaginalis G3
Length = 754
Score = 500 bits (1234), Expect = e-140
Identities = 305/772 (39%), Positives = 446/772 (57%), Gaps = 66/772 (8%)
Query: 25 FQDFLEEFKED--NEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYP 82
F FL +KE+ +E+ Y +++ + E +TL VS++ + +++ A I E YR Y
Sbjct: 15 FLTFLNTYKEEGSDELYYHVQFEKMKEEENTTLRVSYEHLYQFDSTFAEIIAENLYRFYN 74
Query: 83 FLNRAILNYILSLAETGM--KKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQI 140
L A+++++++ + + + +S D + +R++ + +GTLI G +
Sbjct: 75 SLVAALVDFVMAQDKMYAIEGRTHNPRPFALSITDYNVKSALRQIKPSHVGTLIMFQGTV 134
Query: 141 VRTHPVHPELVQGTF-----------------YTIPTICRNPVCANRRRFMLDADKSVFV 183
R V PEL++GTF YT P++C N C N RF L D+S F
Sbjct: 135 TRISDVQPELLKGTFRCRVCGQDIPNVTQNFQYTEPSVCPNKSCNNHSRFELLTDRSEFT 194
Query: 184 DFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPG 243
DFQ+I +QE E P +PR++EVILR + V++ + GDR F G + VP ++ G
Sbjct: 195 DFQRIIVQEDPDESPDSGMPRTMEVILRHQLVDTAKPGDRCQFIGMPVAVPTTAKRAI-G 253
Query: 244 SRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLT 303
R +T Q +G+ G+K GVREL Y+ +FLA SV LP H +
Sbjct: 254 ERPVLTRGAGF----QADGVTGVKGYGVRELTYRLSFLASSV-----------LPLH-IE 297
Query: 304 TEDMRKQM-TDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTT 362
E + M T S+D +Y+ L S+ P I+G+ +VKRG+LLML GGV +
Sbjct: 298 DEILNNNMETPSHMMHEANASQD-TIYDKLARSIAPDIYGHEDVKRGILLMLLGGVQQQA 356
Query: 363 IEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESF 422
+G +RGDINVCIVGDPSTAKSQ LK +S+ PR+VYTSG++SSAAGLTA VV+D E+
Sbjct: 357 -QGMKIRGDINVCIVGDPSTAKSQFLKFISKTMPRSVYTSGQSSSAAGLTATVVKDSETG 415
Query: 423 DFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSIL 482
DF+IEAGALMLADNGVCCIDEFDKM+P DQ AIHEAMEQQTIS+AKAG+ ATLNAR SIL
Sbjct: 416 DFMIEAGALMLADNGVCCIDEFDKMNPTDQTAIHEAMEQQTISIAKAGIHATLNARASIL 475
Query: 483 AAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKE 542
AAANP+ GRY+ A+SL+ N+ L PIMSRFDLFFI+ D+ +E +D IAR+I+++H KE
Sbjct: 476 AAANPVNGRYNTARSLRANLNLPAPIMSRFDLFFIITDDVNEDLDRKIARQIINVHMGKE 535
Query: 543 ESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYY-XXXXXXXXXXXXXXWRITVRQ 601
+ ++S+ +L YI FA+ PV+ ++A +V++Y RITVRQ
Sbjct: 536 VTTKAIFSQHELKTYITFAKRLTPVLKDDAVDAIVKHYVTLRSQDAVGGGGASSRITVRQ 595
Query: 602 LESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLD-EDEPQCEPSMDV 660
LE+++RL+E +AK++ + V P +VHEA RLL SI ++ I L+ D+ EP
Sbjct: 596 LEALIRLSEAIAKLNLAEEVKPTYVHEAARLLTYSISKIGSEPIVLEATDDDVVEPK--T 653
Query: 661 DQDEPNGTAETPSNGDSAPKKKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHK 720
+Q E ET + + F+ Y S++ ++ +R +G
Sbjct: 654 EQKE-----ETVDHN--------VIQFDTYHSIATGIIQRLR------DLATQGRAGETL 694
Query: 721 SAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGL 772
+V+WY E+ + +E++ + +K+I RL+ D V++ TGL
Sbjct: 695 EDLVNWYTEENKDILKYLQSEEMM--ANITKKIILRLIQMDHVLLLNEQTGL 744
>UniRef50_UPI000049880B Cluster: DNA replication licensing factor;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA
replication licensing factor - Entamoeba histolytica
HM-1:IMSS
Length = 682
Score = 495 bits (1222), Expect = e-138
Identities = 280/676 (41%), Positives = 404/676 (59%), Gaps = 44/676 (6%)
Query: 11 SQVKDEVGIRCQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLA 70
++++DE+ + F +F+++++ KYE L++ E +TL + F+D++ ++++++
Sbjct: 23 AKIRDEIADLVSEKFDEFIKQYQMS---KYENEIHLLIENERTTLFIDFNDLQNFDEDVS 79
Query: 71 TTIIEEYYRIYPFLNRAILN----YILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELT 126
+ +YYR L + Y L + KD D + F ++PT VR+L
Sbjct: 80 GALQNQYYRFEKVLVAVAASIGNKYYLQINGIFPLKDTIDA---IGFYNLPTSVTVRKLH 136
Query: 127 TAKIGTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPTICRNPVCAN 169
+ +G L G I R+ V PEL++G F YT P C C N
Sbjct: 137 SNLVGCLTSFYGTITRSSEVRPELIEGVFKCLDCGWESPPIPQQFKYTQPMRCLGSGCTN 196
Query: 170 RRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229
RF L DKS F D+QK+++QE E+P GC+PRS++VILR E VE V+ G F G
Sbjct: 197 TSRFQLLLDKSTFTDWQKVKVQECSNEIPSGCLPRSIDVILRGENVEQVRPGQTCTFIGI 256
Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQME-GIKGLKALGVRELHYKTAFLACSVQAV 288
LI PD LS+ + + + K G++E GIKGL LGVREL YK +F+ +Q
Sbjct: 257 LIAAPDTTRLSVGRNVTAVQEKEK-KRPGELEQGIKGLNDLGVRELVYKLSFICNCIQQS 315
Query: 289 SRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKR 348
+ ++ K +T +E ++V E+S +++ I S P+I G+ +K+
Sbjct: 316 EKS-----------VNNEIDKPLTKEELERVKEISSHPDVFQMFINSFAPNIFGHENIKK 364
Query: 349 GVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSA 408
G+LL+LFGGV KTT EG LRGDIN+C++GDPSTAKSQ LK VS I PR +YTSGKASSA
Sbjct: 365 GILLLLFGGVHKTTKEGIALRGDINICVIGDPSTAKSQFLKCVSTIHPRCIYTSGKASSA 424
Query: 409 AGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAK 468
AGLTAAV++D E+ DF IEAGA+MLADNGVCCIDEFDKMD +QVA+HEAMEQQTIS+AK
Sbjct: 425 AGLTAAVLKDPETGDFNIEAGAMMLADNGVCCIDEFDKMDYFNQVALHEAMEQQTISIAK 484
Query: 469 AGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDY 528
G+ ATLNAR ++LAAANP+ GRYD +SL+ N+ + +MSRFDLFF+++DE +E D
Sbjct: 485 GGLHATLNARAAVLAAANPLKGRYDSNRSLKSNLNIGDALMSRFDLFFVVLDEPNEESDR 544
Query: 529 AIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXX 588
IA IV +H K + S +DL YI A++ P +T+EA +LL + +
Sbjct: 545 RIAEHIVSVHQFKSAALHPPISSNDLKLYIRHAKTITPQLTQEAKELLAKTFADLRKSDM 604
Query: 589 XXXXXX-WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHL 647
+R+TVRQLESM+RL+E +A+++ V +V EA L+ +SI+ VE +
Sbjct: 605 TGKESNPFRMTVRQLESMIRLSEALARLYLDKEVRDDYVKEASNLIKQSIVFVEDKN--- 661
Query: 648 DEDEPQCEPSMDVDQD 663
+E++ + DV D
Sbjct: 662 EEEQGTTNDNEDVIDD 677
>UniRef50_Q4Q826 Cluster: DNA replication licensing factor,
putative; n=6; Trypanosomatidae|Rep: DNA replication
licensing factor, putative - Leishmania major
Length = 880
Score = 476 bits (1174), Expect = e-133
Identities = 265/624 (42%), Positives = 375/624 (60%), Gaps = 30/624 (4%)
Query: 53 STLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVS 112
ST V + D+ +++++ A + ++ R PF+N A+ +L + V
Sbjct: 89 STCVVRWADLLRFDEDAAAVLESDFQRFSPFINEALHQVLLQYYGEEYANRGKCNPSLV- 147
Query: 113 FVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF----------------- 155
F +VP +R L + +G L I G + RT V PEL+ G F
Sbjct: 148 FSNVPRCLTIRSLRASLVGQLCAIKGVVTRTSQVRPELLVGVFRCSDCGTGSLPIEQQFH 207
Query: 156 YTIPTICRNPVCANRRRFML--DADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAE 213
YT P CRNP C N+ +F L + ++ F D+QK+R+QE +P GC+PR++EVI+RA+
Sbjct: 208 YTEPPTCRNPQCENKNKFQLIPNHPQTRFGDWQKLRMQEDANNIPAGCMPRTMEVIVRAD 267
Query: 214 AVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITT------RTKLANEGQMEGIKGLK 267
AVE + GDR G IVVP+V L +R E+ R + + MEG GL+
Sbjct: 268 AVEVAKPGDRILAIGCAIVVPEVAKLFNLANRREVQRQLTGGQRAQQDAQADMEGTTGLR 327
Query: 268 ALGVRELHYKTAFLACSVQAVS---RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSR 324
ALGVR+L+Y+ FLA ++ + R+ A D E +T E +V +M R
Sbjct: 328 ALGVRDLNYRMCFLATTITDATGDDRKMTQAVKEATDGAAEREEVVLTPAERQRVQQMRR 387
Query: 325 DRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAK 384
NL L + + P++ ++ VK G+LL + GGV+KTTIE LRGDINVCIVGDPSTAK
Sbjct: 388 HDNLLKALTSCVAPNVFKHDVVKLGLLLQMVGGVSKTTIERIALRGDINVCIVGDPSTAK 447
Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEF 444
SQ LK VS PR VYTSGKAS+A+GLTA V RD ++ + IEAGALML+D G+CCIDEF
Sbjct: 448 SQFLKWVSANMPRGVYTSGKASTASGLTATVTRDADTGERTIEAGALMLSDRGICCIDEF 507
Query: 445 DKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVAL 504
DKM+ DQVAIHEAMEQQTIS+AKAG++ATLNA+TS+LAA NPIGG+YDR + LQ+N+A+
Sbjct: 508 DKMEMKDQVAIHEAMEQQTISIAKAGIKATLNAKTSLLAALNPIGGKYDRRRPLQKNIAM 567
Query: 505 SPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSF 564
+ PIMSRFDL F+++D+S + D+AIA +++ LH + ++ +D Y+ +ARS
Sbjct: 568 TAPIMSRFDLMFVIVDDSGDDADFAIANQLLRLHRFGGAAVRPPFTTEDFQLYLRYARSL 627
Query: 565 KPVITEEAGKLLV-EYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTP 623
P +T EA +L+V Y +R+T R LESM+RL+E AK++ S V P
Sbjct: 628 TPRLTREASQLIVAAYRDMRLQDSLSNRSKVYRVTTRLLESMIRLSEATAKVYMSDEVRP 687
Query: 624 AHVHEAYRLLNKSIIRVEQPDIHL 647
HV A L+ +S+ ++ ++ L
Sbjct: 688 THVEVALELMRQSLSTLDMTEVEL 711
>UniRef50_Q8SRX5 Cluster: DNA REPLICATION LICENSING FACTOR OF THE
MCM FAMILY; n=1; Encephalitozoon cuniculi|Rep: DNA
REPLICATION LICENSING FACTOR OF THE MCM FAMILY -
Encephalitozoon cuniculi
Length = 726
Score = 459 bits (1132), Expect = e-127
Identities = 264/639 (41%), Positives = 384/639 (60%), Gaps = 53/639 (8%)
Query: 36 NEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSL 95
N K A++ + L V DV Y+ L ++ + R ++R+ Y +
Sbjct: 34 NTPKVRAAAEQAIYRNEGVLLVDLRDVSAYSAELHADLLLNFSRNVERIDRSTAVYTMRE 93
Query: 96 AETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF 155
T ++ + SF + +K+REL + ++G L+ SG + RT V PELV GTF
Sbjct: 94 FSTALE--------HTSFCNSHVIYKIRELKSNRLGQLLSFSGTVTRTTQVRPELVSGTF 145
Query: 156 -----------------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELP 198
YT P C N +C NRR + LD DKS F+++Q+I +QE E+P
Sbjct: 146 VCKICGSVIDNVFQEFKYTEPLTCPNHLCTNRRLWKLDIDKSKFLNWQRIHVQENTEEIP 205
Query: 199 RGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEG 258
G +PRS++VI+R + VE ++AGD+ TG LIVVPDV L MP S++ G
Sbjct: 206 PGSLPRSMDVIVRNDLVEKIRAGDKVVMTGYLIVVPDVVQLMMPQSKSVPM------QSG 259
Query: 259 QMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDK 318
+ + I+ + + +++L++K +F+ C S ED ++ T++E
Sbjct: 260 ESDEIRKKRNINIKDLNHKLSFM-CIHAGCS-------------VEED--EEFTNEELAT 303
Query: 319 VYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVG 378
+ EM +LY L S+FPSIHG+ +K +LL+L GGV K GT LRGDIN+ +VG
Sbjct: 304 ISEMRSTPDLYYKLSQSMFPSIHGHYSIKNAILLLLVGGVGKRAEGGTRLRGDINMLLVG 363
Query: 379 DPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGV 438
DP TAKSQ LKQ S PR+VYTSGK+SSAAGLTA+VV+D E+ +F IEAGALML+D GV
Sbjct: 364 DPGTAKSQFLKQASAFLPRSVYTSGKSSSAAGLTASVVKDGETGEFTIEAGALMLSDTGV 423
Query: 439 CCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSL 498
CCIDEFDKM+ DQV+IHEAMEQQTI+++KAG+ ATLNAR+SILAAANPI GRYD+ K+L
Sbjct: 424 CCIDEFDKMNVKDQVSIHEAMEQQTITISKAGINATLNARSSILAAANPIKGRYDKKKTL 483
Query: 499 QQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES--YDCVYSRDDLLR 556
+QN+ LS P+MSRFDL+F+LID++ D +A +++ H + +S ++R+ +
Sbjct: 484 RQNINLSAPVMSRFDLYFVLIDDADPENDRNVATHVLNSHASVTDSGVLASYFTREQVKL 543
Query: 557 YIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMH 616
Y+ +AR P +T EA ++L++ Y + +TVR LES++RL+E +AK+H
Sbjct: 544 YLRYARKKTPRMTAEAKEMLIKRY-VGIRQDSLIHSNNYMMTVRHLESLIRLSEALAKVH 602
Query: 617 CSGHVTPAHVHEAYRLLNKSIIRVEQPDIHL---DEDEP 652
+ VT +V EA+RL+ S++ V+ DI + DEP
Sbjct: 603 DNDLVTKEYVEEAHRLVKSSVVEVKGEDIEIIPKTADEP 641
>UniRef50_A7APV6 Cluster: MCM2/3/5 family protein; n=1; Babesia
bovis|Rep: MCM2/3/5 family protein - Babesia bovis
Length = 918
Score = 441 bits (1087), Expect = e-122
Identities = 277/778 (35%), Positives = 426/778 (54%), Gaps = 77/778 (9%)
Query: 66 NQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTR-HKVRE 124
N L +++ + R++ L + + + S+A + + + K+ ++ F+ P+ +++++
Sbjct: 139 NMQLYKYVVKYFLRVHDVLEDKLQDIVDSIA---LSFNREPKKLFLQFLHTPSVVYRLKD 195
Query: 125 LTTAKIGTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPTICRNPVC 167
L +G L+ ISGQ+ RT V PEL++GTF YT+P C + C
Sbjct: 196 LRCHMLGELLTISGQVTRTSDVRPELIRGTFKCKACGSFIRDIRQNFRYTVPNKCSSNSC 255
Query: 168 ANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFT 227
N + L + S+F D+QK+RIQE E +PRS++VILR V+ + AGDR +
Sbjct: 256 MNTAEWELVMEHSIFCDWQKVRIQELAQESGMSSMPRSIDVILRHLTVDRLNAGDRVTIS 315
Query: 228 GTLIVVPDVGALSMPGSRAEITTRTKLAN-EGQM--EGIKGLKALGVRELHYKTAFLACS 284
G+LIV+PD+ L PG ++ + E + +G+ G+ +G ++L++K +FLA
Sbjct: 316 GSLIVLPDIPTLLKPGEMPRKVSKQSMRRFESHLISQGLTGIHGVGTKDLNHKLSFLATQ 375
Query: 285 VQAVSRRFGTAELPTHDLTTEDMRKQ--MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHG 342
V+ V+ A +R + + +D + +++ N + L + P I G
Sbjct: 376 VRRVNDYKSHANDIVDSGDGYQIRGEDILRLPNFDWLRRIAQCHNTIDRLAVCVAPKIWG 435
Query: 343 NNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTS 402
++E+K+G+LLM+ GGV K++ + LRGDINVC+VGDPSTAKSQ LK V PRA+ TS
Sbjct: 436 HSEIKKGILLMMVGGVHKSS-SNSKLRGDINVCLVGDPSTAKSQFLKFVEGFAPRAINTS 494
Query: 403 GKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQ 462
GK S+AAGLTAAV RD +S +FV+EAGALM AD G+CCIDEFDKM D+VAIHEAMEQQ
Sbjct: 495 GKGSTAAGLTAAVHRDPDSGEFVLEAGALMYADKGICCIDEFDKMSERDRVAIHEAMEQQ 554
Query: 463 TISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDES 522
TIS+AKAG++ATLNAR S+LA NP GRYD++KS NV L PP++SRFDL + ++DE+
Sbjct: 555 TISIAKAGIQATLNARASVLAVCNPRYGRYDQSKSFASNVNLPPPLLSRFDLLYTMLDEA 614
Query: 523 SEMVDYAIARKIVDL-----------------HCNKEESYDCVY----SRDDLLRYIAFA 561
E +D IA I L H + E +D + + D+L YI A
Sbjct: 615 DEEIDAKIAWHITGLHGPGAYKSSDVIGSSEEHADSEIPFDQEFNPPLTLDELKLYIELA 674
Query: 562 RSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHV 621
+ KP++ + A L +YY RITVRQLES+VRL+E +A++ S V
Sbjct: 675 KRIKPLMQDSAKHKLAQYYVGLRNGDAQSAKRSLRITVRQLESLVRLSEAIARLKFSDFV 734
Query: 622 TPAHVHEAYRLLNKSIIRVEQPD-IHLDEDEPQCEPSMDVDQD---EPNGTAETPSNGDS 677
+HV EAY + S++R+ D I L+ + + + MD D E + AET N D
Sbjct: 735 DESHVDEAYNIFKSSLLRLSNKDLIVLEGESGEKDAEMDGSDDEYVEEHRPAETAGNSD- 793
Query: 678 APKKKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQI 737
+ + EY+++S +L+ + + ++ WY++ +V
Sbjct: 794 ----LIRIGMNEYEAISAVLL-------DRVSEHQLLDEEVASNELIEWYVQNVVVPRTP 842
Query: 738 ESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLRGTQKSSEQDIEDDPLLVVHPNY 795
E D R +++V+ RL+Y D+ ++ + + DI + L VHPNY
Sbjct: 843 EDADAWNLR---LQRVVHRLVYVDKKLL----------ARRRDDDIPNVFRLRVHPNY 887
>UniRef50_A5K2F8 Cluster: DNA replication licensing factor MCM6,
putative; n=7; Plasmodium|Rep: DNA replication licensing
factor MCM6, putative - Plasmodium vivax
Length = 944
Score = 430 bits (1059), Expect = e-119
Identities = 266/709 (37%), Positives = 397/709 (55%), Gaps = 59/709 (8%)
Query: 120 HKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPTIC 162
H +R L +G +I + GQ+ RT V PEL F YT P+ C
Sbjct: 219 HSLRSLRCEMLGEMISVRGQVTRTSDVRPELTLAAFKCNECGNIINGVKQQFRYTQPSKC 278
Query: 163 RNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGD 222
+ C+N + L ++S FVD+QKIR+QE E P G +PR+++VILR + V+SV AGD
Sbjct: 279 PSSSCSNMYDWSLVLEQSYFVDWQKIRLQEIAQESPPGSMPRNMDVILRNDIVDSVHAGD 338
Query: 223 RYDFTGTLIVVPDVGALSMPGSRAEITTRTKLA-NEGQM--EGIKGLKALGVRELHYKTA 279
R TG LIVVPD+ L PG R L NE + +G+ G+K +GV++L++K
Sbjct: 339 RIIVTGCLIVVPDIPTLMKPGDIPRSVARQILKKNENSLVSQGLTGIKGVGVQDLNHKLC 398
Query: 280 FLACSVQAV--SRRFGTAELPTH-DLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSL 336
AC ++ + S++ + + T D+ E++ D +W + +++ N + L +
Sbjct: 399 IYACQIEKLNNSKKENSFDEQTQVDINCEEILN-CDDLKW--LRDIAMHPNTIDILAECI 455
Query: 337 FPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITP 396
P I GN E+K+G LLM+ GGV K T LRGDIN+CIVGDP TAKS++LK V P
Sbjct: 456 APKIWGNIEIKKGALLMMTGGVQKIT-SNCKLRGDINMCIVGDPGTAKSEILKYVESFAP 514
Query: 397 RAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIH 456
RA++TSGK S+AAGLTAAV RD + D V+EAGALM AD G+CCIDEFDKMD D+VAIH
Sbjct: 515 RAIFTSGKGSTAAGLTAAVHRDPDQGDTVLEAGALMYADQGICCIDEFDKMDEKDRVAIH 574
Query: 457 EAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFF 516
EAMEQQTIS+ KAG++ATLNAR S+LAA NP GRYD K+ QNV + P++SRFDLF+
Sbjct: 575 EAMEQQTISITKAGIQATLNARASVLAACNPKYGRYDTLKTFAQNVNIPAPLLSRFDLFY 634
Query: 517 ILIDESSEMVDYAIARKIVDLHCNK--EESYDCVYSRDDLLR---YIAFARSFKPVITEE 571
++D D +IA +V +HC + E+ + D ++ Y+ ++ KP++T+E
Sbjct: 635 TMLDSIDIDKDTSIANHLVSMHCGEEAEKHIRANAGKLDTVKMEVYLELSKRVKPLLTDE 694
Query: 572 AGKLLVEYYXXXXXXXXX-XXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAY 630
A L+ YY R+TVRQLES++RL+E VAK+ S V HV A
Sbjct: 695 AKYKLIHYYVSFRNIEYSPGAQRSMRMTVRQLESLIRLSEAVAKLKFSHFVDIKHVEIAC 754
Query: 631 RLLNKSIIRV-EQPDIHLDEDEPQCEPSMDVDQDEPNGTAETPSNGDSAP---KKKLALS 686
+ S+ ++ + +I+LDE+ + S+ + P +G++ P KK + +
Sbjct: 755 SIFKASMKKISNEKEINLDEEFDKVSNSL---LNSKTSKIIQPEDGENKPVESKKVMTIK 811
Query: 687 FEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELLER 746
EY+ +S ++ +++ S + + ++ YL+ E DE + +
Sbjct: 812 ASEYQYISAIIFEIIKE-----YEFNNNSESITQDQLIETYLQVYAKAESSEHVDEWIYK 866
Query: 747 KTLVEKVIDRLMYHDQVIIPLSTTGLRGTQKSSEQDIEDDPLLVVHPNY 795
++K+I RL+ D ++ + +E D D+ +L +HPNY
Sbjct: 867 ---LKKIIHRLINQDMKLL----------SEINEAD-PDNAILRIHPNY 901
>UniRef50_Q4SNX1 Cluster: Chromosome 15 SCAF14542, whole genome
shotgun sequence; n=2; Clupeocephala|Rep: Chromosome 15
SCAF14542, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 996
Score = 405 bits (998), Expect = e-111
Identities = 244/516 (47%), Positives = 322/516 (62%), Gaps = 90/516 (17%)
Query: 366 TTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFV 425
+TLR + I P +A+ + V E +PRAVYTSGKASSAAGLTAAVVRDEES +FV
Sbjct: 487 STLRRRDSQIIHPSPPSAR---FRHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFV 543
Query: 426 IEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAA 485
IEAGALMLADNGVCCIDEFDKMD DQVAIHEAMEQQTIS+ KAGV+ATLNARTSILAAA
Sbjct: 544 IEAGALMLADNGVCCIDEFDKMDVKDQVAIHEAMEQQTISITKAGVKATLNARTSILAAA 603
Query: 486 NPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDES----------------------- 522
NPIGGRYDR+KSL+QNV L+ PIMSRFDLFFIL+D+
Sbjct: 604 NPIGGRYDRSKSLKQNVNLTAPIMSRFDLFFILVDDCNEVRPTFCPRAAARSSSSGLRVV 663
Query: 523 ---SEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEY 579
S++ DYAIAR+IVDLH ++S D +Y+ D++ RY+ FAR FKP I+ E+ + +VE
Sbjct: 664 LPVSQVTDYAIARRIVDLHSRVQDSVDRLYTLDEIRRYLLFARQFKPKISSESEEFIVEQ 723
Query: 580 Y--XXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
Y WRITVRQLESM+RL+EG+A+MHC V P HV EA+RLLNKSI
Sbjct: 724 YKRLRQRDGSGGVSKSAWRITVRQLESMIRLSEGMARMHCCDEVQPKHVKEAFRLLNKSI 783
Query: 638 IRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTA------ETPSNG----DSAPKKKLALSF 687
IRVE PD++L+++E E + + NG A NG S P+ L LSF
Sbjct: 784 IRVETPDVNLEQEEELEEEEEQEEVNGVNGDAGGLNGHADGVNGHAEPGSQPRPSLRLSF 843
Query: 688 EEYKSLSNMLVVYMRKXXXXXXX--------------------XXXXSSGMHKSAVVSWY 727
EYK +SN+LV+++R+ + KSAVV+WY
Sbjct: 844 SEYKRISNLLVLHLRRAEEGEHRRVLHLFRFYCRFLEPVFLLPAAEEEEELKKSAVVNWY 903
Query: 728 LEQLVAQGQIESEDELLERKTLVEKVIDRLMYH-------------------------DQ 762
L+++ + +I+SE+EL+ +K+L+EKV+ RL+++ D
Sbjct: 904 LKEI--ESEIDSEEELVRKKSLIEKVLHRLVHYVSPTSKPLVPPQKTSRCLLTGVLLQDH 961
Query: 763 VIIPLSTTGLRGTQKSSEQDIEDDPLLVVHPNYVVD 798
++I LS GL+G++ +S + E++ +LVV+PNY+++
Sbjct: 962 ILIQLSQAGLKGSESASTE--EEEAVLVVNPNYILE 995
Score = 303 bits (745), Expect = 9e-81
Identities = 157/264 (59%), Positives = 191/264 (72%), Gaps = 25/264 (9%)
Query: 1 MDVADTYATQS--QVKDEVGIRCQKLFQDFLEEFKE-DNEIKYEKHAKELLKPELSTLEV 57
MDVA T + VKDE+ +CQKLFQ FLEEF+ D E+KY + A+EL++PE +TL V
Sbjct: 1 MDVATTTTENAGEMVKDELAEKCQKLFQAFLEEFQSGDGEVKYVREAEELIRPERNTLLV 60
Query: 58 SFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVP 117
SF ++E +NQ LATTI EEYYR+YP+L RA+ N+ + +KE YV+ D+P
Sbjct: 61 SFTELEGFNQELATTIQEEYYRVYPYLCRAVRNFARDHGNVPL-----NKEFYVALEDLP 115
Query: 118 TRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPT 160
TRHK+REL++ +IGTL++ISGQ+VRTHPVHPELV GTF Y+ PT
Sbjct: 116 TRHKIRELSSMRIGTLVKISGQVVRTHPVHPELVSGTFQCLDCQALIRDVPQQFKYSPPT 175
Query: 161 ICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQA 220
ICRNPVC NR RF LD KS F+DFQK+RIQETQAELPRG IPRSLEV+LRAEAVE+ QA
Sbjct: 176 ICRNPVCNNRSRFHLDTHKSKFIDFQKVRIQETQAELPRGSIPRSLEVVLRAEAVETAQA 235
Query: 221 GDRYDFTGTLIVVPDVGALSMPGS 244
GDR DFTGTLIVVPDV L PG+
Sbjct: 236 GDRCDFTGTLIVVPDVSQLRTPGA 259
Score = 73.3 bits (172), Expect = 2e-11
Identities = 33/81 (40%), Positives = 50/81 (61%)
Query: 291 RFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGV 350
+FG E+ + T E ++ QMT+KEW+KV+EMS+D+NLY+NL +SLFP+IHG +
Sbjct: 359 QFGGKEIREEEQTAESIKSQMTEKEWEKVFEMSQDKNLYHNLCSSLFPTIHGGSAPAASR 418
Query: 351 LLMLFGGVAKTTIEGTTLRGD 371
+ G+ G RG+
Sbjct: 419 AVARAAGIQPLPRLGRERRGE 439
>UniRef50_Q4UDH3 Cluster: Replication licensing factor, putative;
n=2; Theileria|Rep: Replication licensing factor,
putative - Theileria annulata
Length = 1021
Score = 376 bits (925), Expect = e-102
Identities = 214/516 (41%), Positives = 310/516 (60%), Gaps = 38/516 (7%)
Query: 57 VSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDV 116
V+ D N L +++ + R+ L + N + ++ + ++ Y+ F+
Sbjct: 127 VNIDAPVNLNVQLYRYLVKNFLRMQEPLEDVLQNLVNEISNAVNRVP---RKFYLQFLHT 183
Query: 117 PTR-HKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF-----------------YTI 158
PT + +RE+ +G LI I GQ+ R V PEL++ TF YT
Sbjct: 184 PTIIYPLREVKCFMLGELICIRGQVTRVSDVRPELIRATFRCKTCGTVVTDIVQQFKYTT 243
Query: 159 PTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESV 218
PT C C N + L D+S F D+QKIRIQE E G +P S++VI+R + V+SV
Sbjct: 244 PTKCPTSSCLNNSDWELMMDRSYFCDWQKIRIQEVAQEAETGAMPCSIDVIMRNKLVDSV 303
Query: 219 QAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQME------GIKGLKALGVR 272
AGDR +G+LIVVPD+ ++ E+ + + E GI G++ +GV+
Sbjct: 304 NAGDRVQISGSLIVVPDIPSMLNATQLGEVAKKVMRQGAKRFETFLLSQGITGIRGVGVK 363
Query: 273 ELHYKTAFLACSVQAVSR---RFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLY 329
+L++K +FLA V V++ F E+ L ED+ ++ EW + E+S R+
Sbjct: 364 QLNHKLSFLATHVTVVNQFRNTFQVGEVDEKFLRAEDLLN-ISGFEW--IREVSSSRDTI 420
Query: 330 NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLK 389
+ L + P++ GN E+K+G+LL+L GGV K++ + LRGDIN+CIVGDPSTAKSQ LK
Sbjct: 421 DRLSRIIAPNVWGNYEIKKGLLLLLVGGVHKSSRDAK-LRGDINMCIVGDPSTAKSQFLK 479
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
V PRAVYTSGK S+AAGLTAAV +D ++ D+V+EAGALM AD G+CCIDEFDKM+
Sbjct: 480 FVESFAPRAVYTSGKGSTAAGLTAAVFKDHDNNDYVLEAGALMYADEGICCIDEFDKMNE 539
Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509
D+VAIHEAMEQQTIS++KAG++ATLNAR S+LAA NP GRYD +KS + NV + P++
Sbjct: 540 RDRVAIHEAMEQQTISISKAGIQATLNARASVLAACNPRYGRYDTSKSFKDNVNIPSPLL 599
Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESY 545
SRFDL + ++DE++ V+ R+I + C + Y
Sbjct: 600 SRFDLLYTILDENNNQVN----RRISEYVCERYNKY 631
Score = 77.8 bits (183), Expect = 1e-12
Identities = 64/249 (25%), Positives = 111/249 (44%), Gaps = 26/249 (10%)
Query: 552 DDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEG 611
D+L YI + KP++ + A + L EYY R+TVRQLES+VRL+E
Sbjct: 749 DELRLYIELCKRLKPLMQDSAKRKLSEYYVELRNGDVQLGKRSLRMTVRQLESLVRLSEA 808
Query: 612 VAKMHCSGHVTPAHVHEAYRLLNKSIIRVE-----QPDIHLDEDEPQCEPSMDVDQDEPN 666
VAK+ S VT HV AY + S++++ Q L + +P E
Sbjct: 809 VAKLKFSDFVTSHHVQIAYDIFKSSLLKLTNKTTIQLTTGLKDTSRSSQPDTSRRSSEEA 868
Query: 667 GTAETPSNGDSAPKKKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHKSAVVSW 726
AE S G + +++ ++Y ++ ++L+ + + + ++ W
Sbjct: 869 AEAEQES-GKAYDNMTMSIGLDKYNAIISVLL-------DKVGEHELTGNLILNNELIEW 920
Query: 727 YLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLRGTQKSSEQDIEDD 786
YLE ++ ++E+E E ++ +I RL + D +I +++D E+
Sbjct: 921 YLENILVP---KTEEEANEWNLKLQHIIYRLAFVDSKLI----------ASQADEDPENI 967
Query: 787 PLLVVHPNY 795
L VHPNY
Sbjct: 968 YRLRVHPNY 976
>UniRef50_P30665 Cluster: Cell division control protein 54; n=18;
Eukaryota|Rep: Cell division control protein 54 -
Saccharomyces cerevisiae (Baker's yeast)
Length = 933
Score = 328 bits (806), Expect = 3e-88
Identities = 225/632 (35%), Positives = 338/632 (53%), Gaps = 48/632 (7%)
Query: 35 DNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQ--NLATTIIEEYYRIYPFLNRAILNYI 92
D E+ Y K E+ + S L + ++ Y Q +L ++ + +++ I + +
Sbjct: 221 DEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCM 280
Query: 93 LSL-AETGMKKDLQDKECYVSFV---DVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHP 148
+SL + + DL + E V +V + +REL I LI + G ++R+ PV P
Sbjct: 281 VSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIP 340
Query: 149 ELVQGTF------YTI-----------PTICRNPVCANRRRFMLDADKSVFVDFQKIRIQ 191
++ F +T+ P C C L ++ F D Q I++Q
Sbjct: 341 DMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQ 400
Query: 192 ETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTR 251
ET +P G P S+ + + E V+S +AGDR + TGT +P RA R
Sbjct: 401 ETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIP---------IRANSRQR 451
Query: 252 TKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQM 311
+ + +K + + L T+ + + + + E+ E++R Q+
Sbjct: 452 VLKSLYKTYVDVVHVKKVSDKRLDVDTSTI--EQELMQNKVDHNEV-------EEVR-QI 501
Query: 312 TDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGD 371
TD++ K+ E++ +LY+ L S+ PSI+ +VK+G+LL LFGG KT +G RGD
Sbjct: 502 TDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGD 561
Query: 372 INVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGAL 431
IN+ + GDPST+KSQ+L+ V +ITPR VYTSGK SSA GLTA + RD ++ V+E+GAL
Sbjct: 562 INILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGAL 621
Query: 432 MLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGR 491
+L+D GVCCIDEFDKM + +HE MEQQTIS+AKAG+ TLNAR+SILA+ANPIG R
Sbjct: 622 VLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSR 681
Query: 492 YDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC-NKEE--SYDCV 548
Y+ + +N+ L PP++SRFDL ++++D+ E D +A+ + +L+ +K E S D V
Sbjct: 682 YNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDV 741
Query: 549 YSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRI--TVRQLESM 605
+ L YI++A+ P+ITE A LV Y RI T RQLESM
Sbjct: 742 LPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESM 801
Query: 606 VRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
+RLAE AKM V V EA RL+ +I
Sbjct: 802 IRLAEAHAKMKLKNVVELEDVQEAVRLIRSAI 833
>UniRef50_A1CSW6 Cluster: DNA replication licensing factor MCM4;
n=13; Ascomycota|Rep: DNA replication licensing factor
MCM4 - Aspergillus clavatus
Length = 1023
Score = 322 bits (790), Expect = 3e-86
Identities = 205/542 (37%), Positives = 296/542 (54%), Gaps = 48/542 (8%)
Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPTICRN 164
+R+L A + L+ I G ++RT P+ P++ + F PT C
Sbjct: 400 MRDLDPADMDKLVSIKGLVIRTTPIIPDMKEAFFRCQICNHGVQVDIDRGKIAEPTECPR 459
Query: 165 PVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRY 224
PVC R L ++ VF D Q I++QET +P G P S+ + + E V+ +AGDR
Sbjct: 460 PVCKERNSMQLIHNRCVFADKQVIKLQETPDSIPDGQTPHSVSLCVYDELVDVCKAGDRV 519
Query: 225 DFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKG-LKALGVRELHYKTAFLAC 283
+ TG P I R + Q K + L V+++ K L
Sbjct: 520 EVTGIFRCNP-----------VRINPRQRT----QKSLFKTYIDVLHVQKIDRKK--LGI 562
Query: 284 SVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGN 343
V + + EL + + ++++ +E +K+ + +LY L SL PSI+
Sbjct: 563 DVSTIEQ-----ELSEQAVGDAEQTRRISAEEEEKIKRTATRPDLYELLARSLAPSIYEM 617
Query: 344 NEVKRGVLLMLFGGVAKTTIEGTT--LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYT 401
++VK+G+LL LFGG KT +G RGDINV + GDPST+KSQLL+ V +I PR VYT
Sbjct: 618 DDVKKGILLQLFGGTNKTFQKGGNPRYRGDINVLLCGDPSTSKSQLLRYVHKIAPRGVYT 677
Query: 402 SGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQ 461
SGK SSA GLTA V RD E+ V+E+GAL+L+D G+CCIDEFDKM+ + +HE MEQ
Sbjct: 678 SGKGSSAVGLTAYVTRDPETRQLVLESGALVLSDGGICCIDEFDKMNESTRSVLHEVMEQ 737
Query: 462 QTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDE 521
QT+S+AKAG+ TLNARTSILA+ANPIG RY+ + QN+ L P ++SRFDL ++++D
Sbjct: 738 QTVSIAKAGIITTLNARTSILASANPIGSRYNPNLPVPQNIDLPPTLLSRFDLVYLVLDR 797
Query: 522 SSEMVDYAIARKIVDLHCN---KEESYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLV 577
E D +A+ +V+++ + + + + L YI +A++ PV+T AGK L
Sbjct: 798 VDEQEDRRLAKHLVNMYLEDRPDNAAEEEILPIEFLTAYITYAKTKVHPVLTPAAGKALS 857
Query: 578 EYYXXXXXXXXXXXXXXWRI--TVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNK 635
+ Y RI T RQLESM+RL+E A+M S VT V EA RL+
Sbjct: 858 DAYVNMRKLGDDIRSHDRRITATTRQLESMIRLSEAHARMRLSTEVTADDVEEAVRLIRS 917
Query: 636 SI 637
+I
Sbjct: 918 AI 919
>UniRef50_Q9UXG1 Cluster: Minichromosome maintenance protein MCM;
n=4; Sulfolobaceae|Rep: Minichromosome maintenance
protein MCM - Sulfolobus solfataricus
Length = 686
Score = 321 bits (788), Expect = 5e-86
Identities = 215/617 (34%), Positives = 342/617 (55%), Gaps = 43/617 (6%)
Query: 24 LFQDFLEEFK-EDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYP 82
+F +FL FK +N+ KY + EL+ +L + F DV +N+NLA II I P
Sbjct: 13 VFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILP 72
Query: 83 FLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVR 142
L A+ ++IL L T ++D++ + +V V +P ++R++ + IG LI I G +V+
Sbjct: 73 ILEGALYDHILQLDPT-YQRDIE--KVHVRIVGIPRVIELRKIRSTDIGKLITIDGILVK 129
Query: 143 THPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202
PV + + T+ I +P C + D + ++ I + + R I
Sbjct: 130 VTPVKERIYKATYKHI-----HPDCMQEFEWPEDEEMPEVLEMPTICPKCGKPGQFR-LI 183
Query: 203 PRSLEVILRAEAV-----ESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANE 257
P ++I +AV E V +G + +I+ D+ + PG R ++T + +
Sbjct: 184 PEKTKLIDWQKAVIQERPEEVPSG-QLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQD 242
Query: 258 GQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWD 317
++ +G +A V +++ K + + S + + ++ ED +K
Sbjct: 243 SPVK--RGSRA--VFDIYMKVSSIEVSQKVLDEVI---------ISEEDEKK-------- 281
Query: 318 KVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIV 377
+ ++++D + + +I+S+ PSI+G+ E+K + L LFGGV K +E T +RGDI++ I+
Sbjct: 282 -IKDLAKDPWIRDRIISSIAPSIYGHWELKEALALALFGGVPKV-LEDTRIRGDIHILII 339
Query: 378 GDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNG 437
GDP TAKSQ+L+ +S + PRAVYT+GK S+AAGLTAAVVR++ + ++ +EAGAL+LAD G
Sbjct: 340 GDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGG 399
Query: 438 VCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKS 497
+ IDE DKM D+VAIHEAMEQQT+S+AKAG+ A LNAR +++AA NP GRY +
Sbjct: 400 IAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERP 459
Query: 498 LQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRY 557
+ N+ L P I+SRFDL FIL D+ E D +A I+D+H K S + D L +Y
Sbjct: 460 VSDNINLPPTILSRFDLIFILKDQPGEQ-DRELANYILDVHSGK--STKNIIDIDTLRKY 516
Query: 558 IAFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMH 616
IA+AR + P IT EA L+ +++ IT RQLE+++R++E AKM
Sbjct: 517 IAYARKYVTPKITSEAKNLITDFFVEMRKKSSETPDSPILITPRQLEALIRISEAYAKMA 576
Query: 617 CSGHVTPAHVHEAYRLL 633
VT A ++
Sbjct: 577 LKAEVTREDAERAINIM 593
>UniRef50_Q5K7N5 Cluster: DNA unwinding-related protein, putative;
n=2; Basidiomycota|Rep: DNA unwinding-related protein,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 989
Score = 316 bits (777), Expect = 1e-84
Identities = 207/556 (37%), Positives = 297/556 (53%), Gaps = 38/556 (6%)
Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF------YTI-----------PTICRN 164
+R+L L+ + G ++R PV P++ F +T+ P C
Sbjct: 345 MRDLNPGDTDKLVTVKGLVIRATPVIPDMTTAFFRCLVCQHTVQADIDRGRISEPERCPR 404
Query: 165 PVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRY 224
VC + L ++S F D Q IR+QET +P G P ++ + + E V+ V+ GDR
Sbjct: 405 DVCGSTGTMSLIHNRSEFTDKQVIRLQETPDAVPDGQTPHTVSLCVYDELVDLVKPGDRV 464
Query: 225 DFTGTLIVVP------DVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKT 278
TG +P S+ + ++ K N +M +A +
Sbjct: 465 IITGIFRSIPVRVNPRQRSIKSLYKTYLDVV-HVKRTNTARMGFDPSTRAGESKPPGVGV 523
Query: 279 AFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFP 338
+ ++R+ G A + DL + +R + E ++ E+S +LYN L +SL P
Sbjct: 524 GGEDDEDELLARQDGDAAMD-EDLGSP-VRSAAAEME-QRIIELSNHPDLYNILASSLAP 580
Query: 339 SIHGNNEVKRGVLLMLFGGVAKTTIEG-----TTLRGDINVCIVGDPSTAKSQLLKQVSE 393
SI+ +VK+G+LL LFGG K+ G RGDINV +VGDP T+KSQ+L+ V +
Sbjct: 581 SIYELEDVKKGILLQLFGGTNKSIARGGGGGGPRYRGDINVLMVGDPGTSKSQILQYVHK 640
Query: 394 ITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQV 453
I PR VYTSGK SSA GLTA V RD +S V+E+GAL+L+D GVCCIDEFDKM +
Sbjct: 641 IAPRGVYTSGKGSSAVGLTAYVTRDPDSKQLVLESGALVLSDGGVCCIDEFDKMSDATRS 700
Query: 454 AIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFD 513
+HE MEQQT+S+AKAG+ TLNARTSILAAANPI RYD + N+ L P ++SRFD
Sbjct: 701 VLHEVMEQQTVSIAKAGIITTLNARTSILAAANPINSRYDPNLPIPANIDLPPTLISRFD 760
Query: 514 LFFILIDESSEMVDYAIARKIVDLHCN--KEESYDCVYSRDDLLRYIAFARS-FKPVITE 570
L ++++D+ E+ D +A+ +V L+ + +++ D + L YI +ARS PV+TE
Sbjct: 761 LLYLVLDKVDEVNDRKLAKHLVGLYLSDVEDQPADNIIPLQTLTSYITYARSKIHPVLTE 820
Query: 571 EAGKLLVEYYXXXXXXXXXXXXXXWRI--TVRQLESMVRLAEGVAKMHCSGHVTPAHVHE 628
A + LV+ Y RI T RQLESM+RL E A+M S V + E
Sbjct: 821 GASEALVQAYVEMRKAGMDSRTQEKRITATTRQLESMIRLGEAHARMRLSDRVEEEDIRE 880
Query: 629 AYRLLNKSIIRVEQPD 644
A RL+ KS +R D
Sbjct: 881 AVRLI-KSALRESATD 895
>UniRef50_A4SAW6 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein -
Ostreococcus lucimarinus CCE9901
Length = 755
Score = 312 bits (767), Expect = 2e-83
Identities = 214/641 (33%), Positives = 329/641 (51%), Gaps = 46/641 (7%)
Query: 22 QKLFQDFLEEFK--EDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYR 79
Q+ F+ F+E F+ + + Y++ +E+ + E + L++ V +Y++ L +I
Sbjct: 34 QQRFRRFIENFELPDSADSYYDERMREIYEKEHTHLDLDCQHVHEYDEFLYKQLIHYPQE 93
Query: 80 IYPFLNRAILNYILS--LAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRIS 137
I P + Y L +A M +D V ++ +R+L + I ++ +
Sbjct: 94 IIPLFDVVANEYFLENVVAPEDMDEDTPAARIIVRPFNMMDAKPMRDLNPSDIDKMVCVR 153
Query: 138 GQIVRTHPVHPELVQGTFYTIPT--------ICRNPV---------CANRRRFMLDADKS 180
G + R + P+L F + + R V C L ++
Sbjct: 154 GMVTRCTTIIPDLKLAYFKCLMCGFAPEHVQVDRGRVNEPPLKCTECGKPGTMTLIHNQC 213
Query: 181 VFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALS 240
VF + Q +++QET +P G P ++ + + E V+ + GDR + TG VP
Sbjct: 214 VFANKQTVKMQETPDAIPEGETPHTVSMCVFDELVDQAKPGDRVEVTGVYRAVP------ 267
Query: 241 MPGSRAEITTRT-KLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPT 299
R T RT K + ++ I K G R + A + + + +AE +
Sbjct: 268 ---IRISSTRRTLKSVYKTYLDIIHIRKDAGNRMRN-----TAGTEDDEAAKHSSAERAS 319
Query: 300 HDLTTEDMRKQM--TDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGG 357
+ ++ Q+ T ++ E+ R ++Y L+ SL PSI +VK+G+L LFG
Sbjct: 320 KPASNQNPNAQLEFTPARTAEIEELGRSPDIYQRLVASLAPSIWELEDVKKGLLCQLFGA 379
Query: 358 VAKTTIEGTT---LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAA 414
KT GT +RGDINV +VGDP AKSQLL V I PR +YTSG+ SSA GLTA
Sbjct: 380 TNKT-FSGTAANKVRGDINVLLVGDPGVAKSQLLTYVHRIAPRGMYTSGRGSSAVGLTAY 438
Query: 415 VVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRAT 474
V RD ES D V+E+GAL+L+D G+CCIDEFDKM + +HE MEQQT+S+AKAG+ A
Sbjct: 439 VTRDPESKDMVLESGALVLSDRGICCIDEFDKMSDSARSMLHEVMEQQTVSIAKAGIIAV 498
Query: 475 LNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKI 534
LNARTS+LA+ANP+G RY+ S+ +N+ L P ++SRFDL ++L+D ++ D +AR +
Sbjct: 499 LNARTSVLASANPVGSRYNPNMSMVENIQLPPTLLSRFDLLYLLLDRANPETDRRLARHL 558
Query: 535 VDLHC-NKEESYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXX 592
V LH + + L Y++FARS +PV+++EA + LVE Y
Sbjct: 559 VSLHYKDPPQKKRGAIEASLLTDYVSFARSHVQPVLSDEAAEELVEGYVEMRRMGGSRKV 618
Query: 593 XXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
T RQLES++RL+E +A+M S V EA RL+
Sbjct: 619 IT--ATPRQLESLIRLSESLARMRLSVRVDRDDAKEALRLM 657
>UniRef50_P41389 Cluster: DNA replication licensing factor mcm5;
n=20; Dikarya|Rep: DNA replication licensing factor mcm5
- Schizosaccharomyces pombe (Fission yeast)
Length = 720
Score = 312 bits (767), Expect = 2e-83
Identities = 230/674 (34%), Positives = 341/674 (50%), Gaps = 78/674 (11%)
Query: 22 QKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIY 81
+K F F+EEF DN+ Y ++ L + L + + YN++LA ++ + I
Sbjct: 31 EKNFIQFIEEFVIDNDFIYRTQLRDNLVVKQYMLNIDLRHLISYNEDLAHLLLSQPTDIL 90
Query: 82 PFLNRAILNYILSLAETGMKKDLQD-KECYVSFVDVPTRHKVRELTTAKIGTLIRISGQI 140
P A+ L + + C V+ +R LT + I L+R+ G I
Sbjct: 91 PLFESAVTTVAKRLLYRSQENASTNIPTCQVTLRYDANILPIRNLTASHISKLVRVPGII 150
Query: 141 V-------RTHPVH--------PELVQ--GTF--YTIPTICRNPVCANRRR------FML 175
+ R +H ++Q G F +P +C PV ++ F++
Sbjct: 151 IGASTLSCRATALHLVCRNCRATRILQISGGFSGVQLPRVCEAPVLDGEKKDCPMDPFII 210
Query: 176 DADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPD 235
D KS F+D Q +++QE +P G +PR ++L A DRY T +
Sbjct: 211 DHSKSTFIDQQVLKLQEAPDMVPVGELPR--HILLNA---------DRY-LTNQIT---- 254
Query: 236 VGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTA 295
PG+R IT + Q + +K A+ +R + + +Q S G+
Sbjct: 255 ------PGTRCVITGIFSIF---QNKSVKASGAVAIRNPYIRVV----GIQMDSND-GSK 300
Query: 296 ELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLF 355
P +++E ++ E+SR NLY+ + S+ P+I+GN ++K+ + +LF
Sbjct: 301 STPL-----------FSEEEEEEFLEISRTPNLYDIISNSISPAIYGNVDIKKAIACLLF 349
Query: 356 GGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAV 415
G K +G LRGDINV ++GDP TAKSQ LK V + P AVYTSGK SSAAGLTA++
Sbjct: 350 SGSKKILPDGMRLRGDINVLLLGDPGTAKSQFLKFVERLAPIAVYTSGKGSSAAGLTASI 409
Query: 416 VRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATL 475
RD + +F +E GA++LAD G+ CIDEFDKM D+VAIHEAMEQQTIS+AKAG+ L
Sbjct: 410 QRDSVTREFYLEGGAMVLADGGIVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTIL 469
Query: 476 NARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIV 535
N+RTS+LAAANPI GRYD K+ +N+ I+SRFD+ FI+ DE E D IAR ++
Sbjct: 470 NSRTSVLAAANPIFGRYDDMKTPGENIDFQSTILSRFDMIFIVKDEHDETKDRNIARHVI 529
Query: 536 DLHCNKEESYDCV----YSRDDLLRYIAFAR-SFKPVITEEAG-KLLVEYYXXXXXXXXX 589
+LH N +ES + + D RYI + R P + EA KL ++
Sbjct: 530 NLHTNLQESSETLAIGEIPFDKFRRYINYCRHKCAPNLDAEAAEKLSSQFVAIRKLVHQS 589
Query: 590 XXXXXWR----ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRL-LNKSIIRVEQPD 644
R ITVRQLE+++R+ E +AKM S + AH EA RL L ++ Q
Sbjct: 590 EQDSNSRSTIPITVRQLEAIIRITESLAKMSLSPIASEAHATEAIRLFLTSTLAAATQSS 649
Query: 645 IHLDEDEPQCEPSM 658
+ E+ + E S+
Sbjct: 650 PEVTEEVKKIEASL 663
>UniRef50_A7P7V8 Cluster: Chromosome chr3 scaffold_8, whole genome
shotgun sequence; n=8; Eukaryota|Rep: Chromosome chr3
scaffold_8, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 721
Score = 304 bits (746), Expect = 6e-81
Identities = 210/637 (32%), Positives = 324/637 (50%), Gaps = 65/637 (10%)
Query: 28 FLEEFKED---NEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFL 84
FL F+E E KY + +L+ E +L+V DV Y+ +L T ++ YP
Sbjct: 26 FLRHFREHPSHTEGKYMRAIHRVLEIEGESLDVDAHDVFDYDSDLYTKMVR-----YPLE 80
Query: 85 NRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTH 144
AI + +L + L +K ++ T +R L + I ++ + G I+R
Sbjct: 81 VLAIFDIVL-MDMVSRINPLFEKHIQARIFNLKTSTSMRNLNPSDIEKMVSLKGMIIRCS 139
Query: 145 PVHPELVQGTFYTI------------------PTICRNPVCANRRRFMLDADKSVFVDFQ 186
+ PE+ + F + PT C P C + L ++ F D Q
Sbjct: 140 SIIPEIREAVFRCLVCRHYSDPIVVDRGRINEPTTCGRPECLAKNSMTLIHNRCRFADKQ 199
Query: 187 KIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRA 246
+R+QET ++P G P ++ +++ + V+ AG PG R
Sbjct: 200 IVRLQETPDDIPEGGTPHTVSLLMHDKLVD---AGK-------------------PGDRV 237
Query: 247 EITT--RTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTT 304
E+T R G + + L +++ K+ A V G E T L
Sbjct: 238 EVTGIYRAMSVRVGPTQRTTYIDCLHLKKTD-KSRMQAEDPMEVENGSGRNEEDTL-LGY 295
Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364
ED Q+ E+S+ ++Y+ L SL P+I ++VK+G+L LFGG A
Sbjct: 296 EDKVAQLK--------ELSKQPDIYDRLTRSLAPNIWELDDVKKGLLCQLFGGSALKLPS 347
Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDF 424
G + RGDIN+ +VGDP T+KSQLL+ + +++PR +YTSG+ SSA GLTA V +D E+ +
Sbjct: 348 GASFRGDINILLVGDPGTSKSQLLQYIHKLSPRGIYTSGRGSSAVGLTAYVTKDPETGET 407
Query: 425 VIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAA 484
V+E+GAL+L+D G+CCIDEFDKM + +HE MEQQT+S+AKAG+ A+LNARTS+LA
Sbjct: 408 VLESGALVLSDRGICCIDEFDKMSDNARSMLHEVMEQQTVSIAKAGIIASLNARTSVLAC 467
Query: 485 ANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544
ANP G RY+ S+ N+ L P ++SRFDL ++++D++ E D +A+ IV LH ES
Sbjct: 468 ANPSGSRYNPRLSVIDNIHLPPTLLSRFDLIYLILDKADEQTDRRLAKHIVALHFENPES 527
Query: 545 YD-CVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITV--R 600
+ V L Y+++AR P +++EA + L Y IT R
Sbjct: 528 LEQDVLDLPTLTAYVSYARKHIHPKLSDEAAEELTRGYVEMRRRGNFPGSSKKVITATPR 587
Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
Q+ES++RL E +A++ S V V EA+RLL ++
Sbjct: 588 QIESLIRLGEALARIRFSEWVEKRDVMEAFRLLEVAL 624
>UniRef50_A0DAC7 Cluster: Chromosome undetermined scaffold_43, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_43,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 745
Score = 291 bits (714), Expect = 5e-77
Identities = 143/324 (44%), Positives = 214/324 (66%), Gaps = 6/324 (1%)
Query: 327 NLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQ 386
+LY L S+ P I G +VK+ +LLM+ GGV+K +G +RGDINV ++GDP AKSQ
Sbjct: 349 DLYMKLAKSIAPEIFGMEDVKKALLLMIVGGVSKEMHDGLKIRGDINVALIGDPGVAKSQ 408
Query: 387 LLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDK 446
LL+ +S+++PR VYT+GK SS+ GLTAAV+RD + + +E GAL++AD GVCCIDEFDK
Sbjct: 409 LLRYISQVSPRGVYTTGKGSSSVGLTAAVIRDPITGEMALEGGALVMADRGVCCIDEFDK 468
Query: 447 MDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSP 506
M+ D+ AIHE MEQQT+S+AKAG+ TLNARTSILAAANP+ GRY++ ++ QN+ L
Sbjct: 469 MNESDRTAIHEVMEQQTVSIAKAGITTTLNARTSILAAANPLYGRYNKKQTPHQNINLPA 528
Query: 507 PIMSRFDLFFILIDESSEMVDYAIARKIVDLHCN--KEESYDCVYSRDDLLRYIAFARSF 564
++SRFDL FIL+DE + D +A I +H N KE +YS +++ ++A ++ +
Sbjct: 529 ALLSRFDLIFILLDEINHEADTKLASHIGRVHQNKYKENETQDLYSVEEITTFVALSKQY 588
Query: 565 KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITV-RQLESMVRLAEGVAKMHCSGHVTP 623
+P++T + + + + Y + T R L +++RL++ +AK+ + VT
Sbjct: 589 EPILTSDIHQYIADQYVERRKQTFDKTLDGYSYTTPRTLLAIIRLSQSIAKLQLADRVTQ 648
Query: 624 AHVHEAYRLLN---KSIIRVEQPD 644
V EA RL++ +S+ R +Q D
Sbjct: 649 RDVEEAIRLMDISQESVRRAQQID 672
Score = 52.0 bits (119), Expect = 6e-05
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 21/137 (15%)
Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPEL-----------------VQGTFYTIPTICRN 164
+R L IG+LI I +VRT V P++ V G +T C +
Sbjct: 164 IRNLKAQLIGSLITIKAMVVRTSEVRPQIIVACFSCDACGYENYQTVHGKTFTPMLDCAS 223
Query: 165 PVCAN---RRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEA-VESVQA 220
C + R R + + S F+ Q+I+IQE + +LP+G IPR+ V+ R ++ +
Sbjct: 224 DKCRDNKVRGRLIFNHGSSKFISNQEIKIQELKEQLPKGSIPRAFTVMARGDSNIRICSP 283
Query: 221 GDRYDFTGTLIVVPDVG 237
GD G + V G
Sbjct: 284 GDMVTIQGVFLPVEKEG 300
>UniRef50_Q552W6 Cluster: MCM family protein; n=2; Dictyostelium
discoideum|Rep: MCM family protein - Dictyostelium
discoideum AX4
Length = 886
Score = 288 bits (707), Expect = 3e-76
Identities = 174/529 (32%), Positives = 287/529 (54%), Gaps = 22/529 (4%)
Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSV 181
+R+L + I +I ISG I+R+ + PE+ Q F +C AN + +
Sbjct: 272 MRDLNPSDIDKIISISGLIIRSSSIIPEIKQAFFMC--AVCEATFHANVEKGKIQEPS-- 327
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSM 241
+ + +++ + + C+ + I E +++ G+ T L D+ ++
Sbjct: 328 --ECSNCKSKQSLSIIHNRCLFGDKQYIKLQETPDAIPEGET-PHTVALFAYGDLIDIAK 384
Query: 242 PGSRAEITTRTKLA--NEGQMEGIKGLKALGVRELHYKTAFLAC--------SVQAVSRR 291
PG R E+T K + G ++ + + LH K
Sbjct: 385 PGDRVELTGVFKASPMRAGSNRSLRSIYKTYIDILHIKRTDKGKYDDDDDDHDDNTGGGG 444
Query: 292 FGTAELPTHDLTTEDMRK-QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGV 350
GT + +L ED+ + +++++ ++ E+S+ ++Y+ + S+ P+I ++K+G+
Sbjct: 445 TGTGKETNENLDFEDLDEFDLSEEKEREIIELSKKPDIYDIVTKSIAPNIWELEDIKKGI 504
Query: 351 LLMLFGGVAKTTIE-GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409
L LFGG K+ + G RGDIN+ + GDP T+KSQLL V +I PR +YTSGK SSA
Sbjct: 505 LCQLFGGSKKSYQDYGGKFRGDINILLCGDPGTSKSQLLSYVHKIAPRGIYTSGKGSSAV 564
Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469
GLTA + +D ++ + V+E+GAL+L+D GVCCIDEFDKM+ + +HE MEQQT+S+AKA
Sbjct: 565 GLTAYITKDPDTKETVLESGALVLSDKGVCCIDEFDKMNDQTRSILHEVMEQQTVSIAKA 624
Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529
G+ TLNARTSILA+ANP G RY S+ +N+ L P ++SRFDL ++++D+++E D
Sbjct: 625 GIICTLNARTSILASANPSGSRYMPKLSVVENIQLPPTLLSRFDLIYLVLDKANERSDRQ 684
Query: 530 IARKIVDLHCNKEESYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXX 588
+AR +V ++ ++ ++ L YI +AR P +T+++ K LV+ Y
Sbjct: 685 LARHLVSMYWDETPVSHFTIPKETLTNYIQYARKHINPKLTDDSAKCLVQGYLEMRSMGS 744
Query: 589 XXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
T RQLES++R+AE A++ S V P V EA RL+ ++
Sbjct: 745 SKKTIS--ATPRQLESLIRIAEAHARIRFSEFVEPLDVEEAIRLIKVAL 791
>UniRef50_Q8ZY88 Cluster: DNA replication licensing factor; n=6;
Thermoproteales|Rep: DNA replication licensing factor -
Pyrobaculum aerophilum
Length = 680
Score = 288 bits (707), Expect = 3e-76
Identities = 154/334 (46%), Positives = 217/334 (64%), Gaps = 3/334 (0%)
Query: 301 DLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAK 360
D +++ +++T ++ K+ E+SR ++ +I S+ PSI+G EVK V +LFGG
Sbjct: 252 DTMNKELVEEITKEDEQKILEISRRPDVRELIIRSIAPSIYGYEEVKEAVACLLFGGNEI 311
Query: 361 TTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEE 420
+G +RGDIN+ ++GDP TAKSQLLK V++I PRAVYT+GK SSAAGLTAAVVRD+
Sbjct: 312 VYPDGVRVRGDINILLIGDPGTAKSQLLKFVAKIAPRAVYTTGKGSSAAGLTAAVVRDKL 371
Query: 421 SFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTS 480
+ +F +EAGAL+LAD GV IDE DKMD D+VA+HEAMEQ T+S++KAG+ ATLNAR +
Sbjct: 372 TGEFYLEAGALVLADKGVAVIDEIDKMDAKDRVALHEAMEQNTVSISKAGIVATLNARAA 431
Query: 481 ILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCN 540
+LAAANP GRY +++ +N+ L ++SRFDL F++ DE E D A+A I+DLH
Sbjct: 432 VLAAANPAFGRYLPNRTVAENIDLPVSLLSRFDLIFVIRDEPREEFDSAVAGHILDLHSG 491
Query: 541 K-EESYDCVYSRDDLLRYIAFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRIT 598
K E++ V D L +YI +AR + +P+++EEA + + +Y IT
Sbjct: 492 KTPEAFRDVLRPDFLRKYIMYARRYVRPILSEEAKERIKAFYLEMRKRYQGPGTAI-AIT 550
Query: 599 VRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRL 632
RQLE+++RL AKM S A RL
Sbjct: 551 ARQLEALIRLTTAEAKMRLSPIAAAEDAERAIRL 584
Score = 75.4 bits (177), Expect = 6e-12
Identities = 61/223 (27%), Positives = 103/223 (46%), Gaps = 20/223 (8%)
Query: 24 LFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83
L +D E NE K ++ +LEV F D+ ++++LA ++E + P
Sbjct: 9 LLRDKFRELVTSNE-KISDEVINIIIQRKRSLEVDFHDILMFDKSLADLVVERPKLVLPE 67
Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVR- 142
++ ++ I+ + K L K Y P +R+L + IG LI+I G + R
Sbjct: 68 ADK-VVREIVEEKDPETAKAL--KRFYFRVRGSPLSVSLRKLRSEYIGRLIKIEGIVTRQ 124
Query: 143 THPVH---------------PELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQK 187
T P H EL+Q + + P C + F L + S ++D+QK
Sbjct: 125 TPPKHFLYKALYRCTQCGYEIELLQELERHVEPPAKCPRCGASKSFTLVTELSQYIDWQK 184
Query: 188 IRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTL 230
+ +QE +LP G +PRS+EV+L + V++V+ GD TG +
Sbjct: 185 VIVQERPEDLPPGQLPRSVEVVLLDDLVDTVKPGDIISLTGVV 227
>UniRef50_UPI00006CCA0D Cluster: MCM2/3/5 family protein; n=1;
Tetrahymena thermophila SB210|Rep: MCM2/3/5 family
protein - Tetrahymena thermophila SB210
Length = 797
Score = 287 bits (704), Expect = 8e-76
Identities = 220/660 (33%), Positives = 339/660 (51%), Gaps = 92/660 (13%)
Query: 21 CQKLFQDFLEEFK---EDNEIKYEKHAKEL-----LKPELSTLE---VSFDDVE--KYNQ 67
C F+ FL EFK D+ +++A E+ +++ LE ++FD ++++
Sbjct: 72 CSNKFEKFLLEFKAIPSDDHDMLDENASEVNIYVEKFNQMAALEQYILTFDGQHLLQFDK 131
Query: 68 NLATTII---EEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRE 124
L +I E +I+ + ++I + ET ++K V+ V++ ++R+
Sbjct: 132 ILYYQLIFFPAEVIQIFDKVAQSIFRERFAQNETQVEKS---NSVLVAVVNINKSTQLRD 188
Query: 125 LTTAKIGTLIRISGQIVRTHPVHPELVQGTF------YTI-----------PTICRNPVC 167
L I L+ I ++R ++PE+ F +++ P C + C
Sbjct: 189 LRHKDINRLVSIKCIVIRVSDIYPEMKMAVFKCSRCSHSVIVPLERAHVDEPNDCES--C 246
Query: 168 ANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFT 227
+ FM+ + S F D Q I+IQE ++ G P++ ++ YD
Sbjct: 247 HTKNSFMIQHNLSHFTDKQYIKIQELPEKVREGETPQTATLMA-------------YDNN 293
Query: 228 GTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQA 287
+V V PG R E+ + A + + I+ L+++ Y T S
Sbjct: 294 ----LVDQV----KPGDRVEVVGVFRAAGVRKNKNIRTLRSV------YNTYIDVVSYSL 339
Query: 288 VSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVK 347
+S++ +L + + K+ K+ E++ N+Y+ LI S+ PSI N +VK
Sbjct: 340 LSKQ----KLQEEKINFSEETKR-------KLQEIADSENVYDKLIKSVAPSIWENTDVK 388
Query: 348 RGVLLMLFGGVAKTTIEG--TTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKA 405
RG+L LFGG KT + + R +IN +VGDPS AKSQ+LK V + PR +YTSGK
Sbjct: 389 RGLLCQLFGGSVKTIHDAKDSRTRAEINCLLVGDPSVAKSQMLKYVHNLVPRGIYTSGKG 448
Query: 406 SSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTIS 465
SSA GLTA V RD ++ + V+E+GAL+L+D G+CCIDEFDKMD + +HEAMEQQ+IS
Sbjct: 449 SSAVGLTAYVTRDPDTKEIVLESGALVLSDLGICCIDEFDKMDENTRTILHEAMEQQSIS 508
Query: 466 LAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEM 525
+AKAG+ ATLN RT+ILA ANPI RYD KS+ N+ L P ++SRFDL +IL+D E
Sbjct: 509 IAKAGIVATLNTRTAILAGANPIDSRYDPKKSVIDNINLPPSLLSRFDLIYILLDNHDER 568
Query: 526 VDYAIARKIVDLHCNKE-----ESYDCVYS------RDDLLRYIAFAR-SFKPVITEEAG 573
D +A I+ L N + + YS +D L++YIA+AR P +T+EA
Sbjct: 569 KDIQLASHILKLFSNSSQHRLTQGQNSGYSDIDIIDKDTLIKYIAYARQEIHPKLTQEAA 628
Query: 574 KLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
LV+ Y T RQLES++R++E +AKM S VT +V EA RL+
Sbjct: 629 DRLVQGYVDMRKVGLSNKVIT--STTRQLESLIRISESLAKMKLSDQVTVENVEEAIRLM 686
>UniRef50_Q22RW4 Cluster: MCM2/3/5 family protein; n=3; Eukaryota|Rep:
MCM2/3/5 family protein - Tetrahymena thermophila SB210
Length = 1681
Score = 286 bits (701), Expect = 2e-75
Identities = 186/544 (34%), Positives = 289/544 (53%), Gaps = 64/544 (11%)
Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHP-----------------ELVQGTFYTIPTICRN 164
+R L + IG L+ I ++RT V P + V +T C +
Sbjct: 1096 IRNLKSEDIGGLVTIKAIVIRTSDVKPMMQVACYICDTCGCELYQTVSSKTFTPLQECIS 1155
Query: 165 PVCANRR---RFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAG 221
C R + ++ SVF +Q+IR+QET ++P+G IPR ++ + V G
Sbjct: 1156 NTCKTNRTKGKVVISPSSSVFQAYQEIRVQETSDQIPQGNIPRRFLILAKGANVNQCSPG 1215
Query: 222 DRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFL 281
D L+ V V +P + +R+ L E +E K K + Y +
Sbjct: 1216 D-------LVTVQGV---FLPSEHDDYLSRSNLIMETFIESYKIQK----EKKSYSDMQI 1261
Query: 282 ACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIH 341
+Q + ++MR++MTD++ +YE+ L S+ P I+
Sbjct: 1262 EEDIQ---------------IKIQEMREEMTDEQ---IYEL---------LARSIAPEIY 1294
Query: 342 GNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYT 401
G +VK+ +LL++ GG + T +G +RGDIN+ ++GDP AKSQLLK ++ ++PR +YT
Sbjct: 1295 GLEDVKKALLLLMVGGTSLETKDGMRIRGDINMAMIGDPGVAKSQLLKHIARVSPRGIYT 1354
Query: 402 SGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQ 461
+GK SS GLTA++++D + + +EAGAL+LAD GVCCIDEFDKM+ D+ +IHE MEQ
Sbjct: 1355 TGKGSSGVGLTASLIKDPITHEMSLEAGALVLADMGVCCIDEFDKMNENDRTSIHEVMEQ 1414
Query: 462 QTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDE 521
QT+S+AKAG+ +LNARTSILAAANP+ GRY++ S +N+ L ++SRFDL FIL+D
Sbjct: 1415 QTVSIAKAGMATSLNARTSILAAANPLYGRYNKKVSPHKNINLPYALLSRFDLVFILLDT 1474
Query: 522 SSEMVDYAIARKIVDLH--CNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEY 579
+SE D +A+ I+ +H +S + + YI+ A+ F+P I +E L
Sbjct: 1475 ASEENDSRLAKHILQVHKTLQPPKSTEETVDAAVIKAYISQAKQFQPTINKELHDFLTSR 1534
Query: 580 YXXXXXXXXXXXXXXWRITV-RQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSII 638
Y + T R L ++RLA+ +AK+ S V+ V EA RL+ +S
Sbjct: 1535 YLEKRKAQNDKSKDGYNYTTPRTLLGILRLAQSLAKLRFSETVSQKDVDEALRLIEESQK 1594
Query: 639 RVEQ 642
V++
Sbjct: 1595 SVQE 1598
>UniRef50_Q5CPI6 Cluster: DNA replication licensing factor MCM6-like
AAA ATpase; n=3; Cryptosporidium|Rep: DNA replication
licensing factor MCM6-like AAA ATpase - Cryptosporidium
parvum Iowa II
Length = 1055
Score = 284 bits (697), Expect = 6e-75
Identities = 140/239 (58%), Positives = 180/239 (75%), Gaps = 2/239 (0%)
Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364
+D+ Q T + K E+S+ N N L + P ++G +++K+G+LL+L GGV K T +
Sbjct: 387 KDLNVQETS--FRKFLEISQHPNGINMLAKYVAPHVYGYSQLKKGILLLLVGGVEKRTKD 444
Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDF 424
LRGDINVCIVGDPSTAKSQ+L+ V+E + R VYTSGK+S+AAGLTA++ RD + DF
Sbjct: 445 NIKLRGDINVCIVGDPSTAKSQILRFVNEFSTRTVYTSGKSSTAAGLTASIHRDPDQGDF 504
Query: 425 VIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAA 484
VIEAGALMLAD G+CCIDEFDKMD D VAIHEAMEQQTIS+ KAGV ATLNAR S+LAA
Sbjct: 505 VIEAGALMLADKGICCIDEFDKMDDKDVVAIHEAMEQQTISITKAGVLATLNARASVLAA 564
Query: 485 ANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE 543
+P+GGRY+ +K+L QNV +S PI+SRFDLFF++ID+ ++ D +A IV LH E
Sbjct: 565 CSPVGGRYNPSKTLSQNVRISAPILSRFDLFFVMIDDPEDVYDEVLASFIVGLHSKATE 623
Score = 130 bits (314), Expect = 1e-28
Identities = 75/197 (38%), Positives = 106/197 (53%), Gaps = 19/197 (9%)
Query: 112 SFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF---------------- 155
SF + +R L K+G L + G I RT V PEL++ F
Sbjct: 137 SFYGLRWIESLRTLRCEKLGKLCSLRGTITRTSDVRPELIKACFECEICGCIVDNVVQQF 196
Query: 156 -YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEA 214
Y++P++C C NR + L + F D+QK+RIQE E+P G +PRS+ VILR +
Sbjct: 197 VYSLPSVCPTKGCGNRTAWQLRLENCDFGDWQKLRIQEHATEIPPGSMPRSMNVILRGDF 256
Query: 215 VESVQAGDRYDFTGTLIVVPDVGALSMPGS--RAEITTRTKLANEGQMEGIKGLKALGVR 272
V+ + GD+ FTG LIV PDV +L PG + R++ NE GI GLK+LGVR
Sbjct: 257 VDKCKPGDKVIFTGMLIVAPDVPSLMKPGEIPSSVYKDRSRSQNEYYNSGISGLKSLGVR 316
Query: 273 ELHYKTAFLACSVQAVS 289
+L Y+ FLAC ++ V+
Sbjct: 317 DLAYRLCFLACHIEVVN 333
Score = 89.0 bits (211), Expect = 4e-16
Identities = 49/128 (38%), Positives = 73/128 (57%), Gaps = 1/128 (0%)
Query: 540 NKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITV 599
N +S + ++D+L +YIA+A++FKP IT A +LV Y RITV
Sbjct: 655 NFSDSNNLQLTKDELNQYIAYAKTFKPCITPAAKTILVRTYKALRMGDATSGAKAMRITV 714
Query: 600 RQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHL-DEDEPQCEPSM 658
RQLES++RL+E VAK+ S VTP HV EA ++ S+ ++ DI L D DE +
Sbjct: 715 RQLESLIRLSEAVAKLRFSYLVTPEHVEEACQIFKSSLSKIRYNDIDLGDLDEYDEDGDE 774
Query: 659 DVDQDEPN 666
+ +++E N
Sbjct: 775 EEEEEEEN 782
>UniRef50_UPI00006CF347 Cluster: MCM2/3/5 family protein; n=1;
Tetrahymena thermophila SB210|Rep: MCM2/3/5 family
protein - Tetrahymena thermophila SB210
Length = 730
Score = 282 bits (692), Expect = 2e-74
Identities = 208/676 (30%), Positives = 336/676 (49%), Gaps = 91/676 (13%)
Query: 22 QKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIY 81
Q+ ++ F EF N+ Y + K+ ++ E+ +D++ YN + +I++
Sbjct: 34 QEGYKRFFSEFLLKNQKVYIEKMKQAVESRKKCFELDLEDLQSYNSDHYQLLIQKPNDYL 93
Query: 82 PFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIV 141
P L +A ++ T + + Q V + +R++ + I LI +SG I
Sbjct: 94 PLLEKAASEAFYTI--TNNRSNFQ-----VFLISTQDPKNLRDIKASSISKLITVSGIIT 146
Query: 142 RT------------------HPVHPELVQGT-FYTIPTICRNPVCANRR----RFMLDAD 178
+ H + E+ QG +IP C+NP +N + +++ +
Sbjct: 147 QATRPYIRSKILYVECSKCHHQLSLEVSQGLGSVSIPPYCKNPNQSNEKCPVDSYVVIPE 206
Query: 179 KSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGA 238
K +D Q++++QE+ ++P G IPR+ + V + G R TG V+
Sbjct: 207 KCTLIDQQRMKLQESPEDIPTGEIPRTFSLCAERYLVNRLAPGTRVVLTGIYQVL----- 261
Query: 239 LSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELP 298
+ I+ +T + + I ++ +G YK L ++ SR F
Sbjct: 262 -----EKTSISNKTISSTNSK---INYIQVVG-----YK---LEDEIKKRSRSF------ 299
Query: 299 THDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGV 358
TTE+ T + K++E + ++ ++F G +++K+ + +LFGG
Sbjct: 300 ----TTEEEEAFQTLSKDPKIFE-----KIGQSIAPAIF----GFDDIKQAIACLLFGGS 346
Query: 359 AKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRD 418
K +G LRGDINV ++GDPST KSQ LK V I P AVYTSGK SSA+GLTA++ RD
Sbjct: 347 KKILQDGIRLRGDINVLLIGDPSTGKSQFLKFVQRIAPNAVYTSGKGSSASGLTASITRD 406
Query: 419 EESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNAR 478
+ +F IE GA++LAD GV CIDEFDKM P D+VAIHEAMEQQTIS+AKAG+ LN+R
Sbjct: 407 PLTGEFQIEGGAMVLADGGVVCIDEFDKMRPEDRVAIHEAMEQQTISIAKAGITTRLNSR 466
Query: 479 TSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
S+LAAANPI G Y+ K+++ + L I+SRFD F++ D ++ D +A +++LH
Sbjct: 467 CSVLAAANPIFGSYNDLKTIEDQIELQTTILSRFDTIFVVRDPKTQEHDQRLAEHVLNLH 526
Query: 539 CNKEE----SYDCVYSRDDLL-------------RYIAFARS-FKPVITEEAGKLLVEYY 580
+ S + ++L +YI++AR+ P +TE + + + Y
Sbjct: 527 MMNNQKNGGSINAAVMEQEMLEQKGVEIELNLLRKYISYARAKIHPRLTERSAQKIQNLY 586
Query: 581 XXXXXXXXXXXXXXWR---ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
ITVRQLE+++RL+E +AK+ S VT H+++A+ L S
Sbjct: 587 VEDRKQSNQGHSSKKHHIPITVRQLEAIIRLSESIAKIQLSEEVTDEHINKAHELFQNST 646
Query: 638 IRVEQPDIHLDEDEPQ 653
+ Q L + PQ
Sbjct: 647 MNAIQNGKELGLELPQ 662
>UniRef50_P29496 Cluster: Minichromosome maintenance protein 5;
n=11; Ascomycota|Rep: Minichromosome maintenance protein
5 - Saccharomyces cerevisiae (Baker's yeast)
Length = 775
Score = 282 bits (692), Expect = 2e-74
Identities = 155/346 (44%), Positives = 214/346 (61%), Gaps = 13/346 (3%)
Query: 312 TDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGD 371
T++E ++ ++SR+ LY L S+ PSI GN ++K+ ++ +L GG K +G LRGD
Sbjct: 350 TEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGD 409
Query: 372 INVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGAL 431
INV ++GDP TAKSQLLK V +++P AVYTSGK SSAAGLTA+V RD + +F +E GA+
Sbjct: 410 INVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAM 469
Query: 432 MLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGR 491
+LAD GV CIDEFDKM D+VAIHEAMEQQTIS+AKAG+ LN+RTS+LAAANPI GR
Sbjct: 470 VLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGR 529
Query: 492 YDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC-------NKEES 544
YD KS N+ I+SRFD+ FI+ D+ +E D +IA ++++H N++E
Sbjct: 530 YDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEE 589
Query: 545 YDCVYSRDDLLRYIAFAR-SFKPVITEEAG-KLLVEYYXXXXXXXXXXXXXXWR----IT 598
S + + RYI + R P ++ +A KL + R IT
Sbjct: 590 NGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPIT 649
Query: 599 VRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPD 644
+RQLE+++R+ E +AK+ S HV EA RL S + D
Sbjct: 650 IRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQD 695
>UniRef50_Q4X1F6 Cluster: DNA replication licensing factor Mcm7,
putative; n=10; Ascomycota|Rep: DNA replication
licensing factor Mcm7, putative - Aspergillus fumigatus
(Sartorya fumigata)
Length = 854
Score = 279 bits (685), Expect = 2e-73
Identities = 142/333 (42%), Positives = 209/333 (62%), Gaps = 7/333 (2%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRG 370
M + K+ + + N+Y L S+ P I+G+ +VK+ +LL+L GGV K +G +RG
Sbjct: 385 MDSRTLRKIEQYQKSGNMYEYLSRSIAPEIYGHLDVKKALLLLLIGGVTKEMGDGMHIRG 444
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGA 430
DIN+C++GDP AKSQLLK ++++ PR VYT+G+ SS GLTAAV+RD + + V+E GA
Sbjct: 445 DINICLMGDPGVAKSQLLKYIAKVAPRGVYTTGRGSSGVGLTAAVMRDPVTDEMVLEGGA 504
Query: 431 LMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGG 490
L+LADNG+CCIDEFDKMD D+ AIHE MEQQTIS++KAG+ TLNARTSILAAANP+ G
Sbjct: 505 LVLADNGICCIDEFDKMDDADRTAIHEVMEQQTISISKAGITTTLNARTSILAAANPLYG 564
Query: 491 RYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC-NKEESYD--- 546
RY+ S +N+ L ++SRFD+ F+++D D +A + +H NK D
Sbjct: 565 RYNPRISPVENINLPAALLSRFDVMFLILDTPQREADEELANHVAYVHMHNKHPEVDDAG 624
Query: 547 CVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWR---ITVRQLE 603
+++ +++ +YIA AR+++PV+ +V Y + +T R L
Sbjct: 625 VLFTPNEVRQYIAKARTYRPVVPSSVSDYMVGAYVRMRKQQKSDEASKKQFSHVTPRTLL 684
Query: 604 SMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKS 636
+VRL++ +A++ S V V EA RL+ S
Sbjct: 685 GVVRLSQALARLRFSEEVIREDVDEALRLIEVS 717
Score = 43.6 bits (98), Expect = 0.021
Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Query: 169 NRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
++ + L S FV FQ+++IQE ++P G IPR+L + + GD D G
Sbjct: 286 SKGQLFLSTRASKFVPFQEVKIQEMADQVPVGHIPRTLTIHCHGSLTRQLNPGDVVDVAG 345
Query: 229 TLIVVPDVGALSMPGSRAEITTRTKL 254
+ P G ++ RA + T T L
Sbjct: 346 IFLPTPYTGFRAI---RAGLLTDTYL 368
>UniRef50_UPI00004991C5 Cluster: DNA replication licensing factor;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA
replication licensing factor - Entamoeba histolytica
HM-1:IMSS
Length = 690
Score = 279 bits (684), Expect = 2e-73
Identities = 187/551 (33%), Positives = 290/551 (52%), Gaps = 25/551 (4%)
Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCAN--RRRFMLDADK 179
+REL KIG L+R+ G + R V P L + Y+ C N + RF L K
Sbjct: 160 IRELRAEKIGKLVRVKGIVTRATDVRP-LARVITYSCEQ-CGNELYQTIIGNRF-LPQYK 216
Query: 180 SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGAL 239
QK T PR ++ I E VE V G T ++V G L
Sbjct: 217 CPSKTCQKGNKTGTLLMQPRASKFVKIQEIRIQELVEEVPMGA----TPRNLIVKVEGPL 272
Query: 240 SMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPT 299
+ ++ T + + K + + K A S++ + + T L
Sbjct: 273 VQLCAPGDVVTIEGIYLPDEFFSRKDMHIGFISNTFMK----AMSIEKQKKNYTTYTL-- 326
Query: 300 HDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVA 359
+ +++ +++D+ D +E +YNNL S+ P I+G ++K+ +LL + G
Sbjct: 327 ----SSEIKTRISDEVKDFPFE-----EIYNNLALSIAPEIYGLEDLKKALLLTVVGAPT 377
Query: 360 KTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE 419
+ +G ++RGDIN +VG+P AKSQLL+ V+ + PR+VYT+GK SS AGLTAAV+RD+
Sbjct: 378 RRMKDGVSIRGDINTLLVGEPGIAKSQLLRAVAGVAPRSVYTTGKGSSGAGLTAAVIRDQ 437
Query: 420 ESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNART 479
+ ++V+E GAL+LAD G+CCIDEFDKMD D+ AI+E MEQQ+IS+AKAG+ +LNAR
Sbjct: 438 LTKEWVLEGGALVLADMGICCIDEFDKMDETDRTAIYEVMEQQSISIAKAGITTSLNARV 497
Query: 480 SILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC 539
SI+AAANPI RYD KS+ +NV L ++SRFDL F+L+D++++ D +A + H
Sbjct: 498 SIVAAANPIKARYDIRKSVSENVNLPAALVSRFDLLFVLLDDATQDFDKELALFVCKSHR 557
Query: 540 NKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITV 599
+ +Y + L +I A++F P++ E +V+ Y IT
Sbjct: 558 GEVGESKAIYDVEFLRAFIGNAKNFNPIVPETLTDYIVDSYVKKRSKPKNKLDDL-IITP 616
Query: 600 RQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEPSMD 659
R L +++RLA+ VA++ S V V EA RL++ S +++ + L+ +P +D
Sbjct: 617 RSLLAIIRLAQSVARLRFSNEVNSQDVDEALRLIDVSRSSIDKFQVGLNLIDPTNTNDID 676
Query: 660 VDQDEPNGTAE 670
DE +E
Sbjct: 677 QLLDEFESKSE 687
>UniRef50_Q8SRS4 Cluster: DNA REPLICATION LICENSING FACTOR OF THE
MCM FAMILY MCM5; n=1; Encephalitozoon cuniculi|Rep: DNA
REPLICATION LICENSING FACTOR OF THE MCM FAMILY MCM5 -
Encephalitozoon cuniculi
Length = 696
Score = 279 bits (683), Expect = 3e-73
Identities = 160/355 (45%), Positives = 214/355 (60%), Gaps = 30/355 (8%)
Query: 309 KQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTL 368
K T++E + ++S+ ++Y + S+ PS++G+ +VKR + MLFGG + + TL
Sbjct: 262 KMFTEEEEESFKKLSK-ADIYERISRSIAPSVYGHEDVKRALACMLFGGTRRVLEDKVTL 320
Query: 369 RGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEA 428
RGDINV ++GDP AKSQLLK + ++P VYTSGK SSAAGLTA+V+RD +F +E
Sbjct: 321 RGDINVLLLGDPGMAKSQLLKFMELVSPVGVYTSGKGSSAAGLTASVIRDSGG-EFYLEG 379
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPI 488
GAL+LADNG+CCIDEFDKMD D+VAIHEAMEQQTIS+AKAG+ LN RTSILAAANP+
Sbjct: 380 GALVLADNGICCIDEFDKMDEHDRVAIHEAMEQQTISIAKAGITTMLNTRTSILAAANPV 439
Query: 489 GGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNK-EESYDC 547
GRYD K+ +N+ I+SRFD FIL D+ D +A+ ++ +H NK E +C
Sbjct: 440 FGRYDDYKTPDENIEFGATILSRFDCIFILKDKHGPN-DIILAKHVLSVHQNKAREDNEC 498
Query: 548 VYSRDD--------------------LLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXX 586
D + RY+ +ARS P ++E A K L YY
Sbjct: 499 QNGLHDDQEEQISGSDRSPDIIPIHTIKRYVQYARSKVFPTLSEAASKQLSRYYVNTRKE 558
Query: 587 XXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKS 636
+ ITVRQLE+++R+ E +AKM S VT HV EA RL S
Sbjct: 559 VRQLEQSTLKRNAIPITVRQLEAIIRIGESLAKMELSQIVTEKHVEEAIRLFKVS 613
Score = 36.7 bits (81), Expect = 2.4
Identities = 20/71 (28%), Positives = 35/71 (49%), Gaps = 1/71 (1%)
Query: 158 IPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVES 217
IP +C C +++ +KS +D Q ++IQE ++P G PR ++L + V
Sbjct: 164 IPRMCDKTECPPDP-YIVIPEKSQVIDVQYVKIQEFFEDIPVGETPRHFSLVLEKKMVNR 222
Query: 218 VQAGDRYDFTG 228
+ G + TG
Sbjct: 223 LIPGSKVVITG 233
>UniRef50_P33991 Cluster: DNA replication licensing factor MCM4;
n=51; Bilateria|Rep: DNA replication licensing factor
MCM4 - Homo sapiens (Human)
Length = 863
Score = 279 bits (683), Expect = 3e-73
Identities = 203/636 (31%), Positives = 325/636 (51%), Gaps = 47/636 (7%)
Query: 21 CQKLFQDFLEEFKEDNEIKYEKHAKELLKP-------ELST-----LEVSFDDVEKYNQN 68
C++ FQ FL+ F + + E ++ +P E++ L V+ + ++ +++N
Sbjct: 162 CKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKN 221
Query: 69 LATTIIEEYYRIYPFLNRAILNYILS-LAETGMKKDLQDKECYVSFVDVPTRHKVRELTT 127
L +I + P + A+ ++ ++ +Q + F + T++ +R L
Sbjct: 222 LYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRP----FNALKTKN-MRNLNP 276
Query: 128 AKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDF-Q 186
I LI ISG ++RT + PE+ + F C+ VCA+ R +D +
Sbjct: 277 EDIDQLITISGMVIRTSQLIPEMQEAFFQ-----CQ--VCAHTTRVEMDRGRIAEPSVCG 329
Query: 187 KIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRA 246
+ + A + + ++I E+ E + AG T L D+ PG R
Sbjct: 330 RCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQT-PHTVILFAHNDLVDKVQPGDRV 388
Query: 247 EITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTED 306
+T + + +K++ YKT + + R A+ H L E
Sbjct: 389 NVTGIYRAVPIRVNPRVSNVKSV------YKT-----HIDVIHYRKTDAKR-LHGLDEEA 436
Query: 307 MRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT---TI 363
+K ++K + + E+SR ++Y L ++L PSI+ + ++K+G+LL LFGG K T
Sbjct: 437 EQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTG 496
Query: 364 EGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD 423
G R +IN+ + GDP T+KSQLL+ V + PR YTSGK SSA GLTA V++D E+
Sbjct: 497 RGK-FRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQ 555
Query: 424 FVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILA 483
V++ GAL+L+DNG+CCIDEFDKM+ + +HE MEQQT+S+AKAG+ LNARTS+LA
Sbjct: 556 LVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLA 615
Query: 484 AANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE 543
AANPI +++ K+ +N+ L ++SRFDL F+L+D E D +A +V L+ EE
Sbjct: 616 AANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEE 675
Query: 544 -SYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQ 601
+ + + L YIA+A S P ++EEA + L+E Y RQ
Sbjct: 676 QAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVS--AYPRQ 733
Query: 602 LESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
LES++RLAE AK+ S V V EA RL +++
Sbjct: 734 LESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREAL 769
>UniRef50_Q979U9 Cluster: DNA replication initiator; n=4;
Thermoplasmatales|Rep: DNA replication initiator -
Thermoplasma volcanium
Length = 699
Score = 277 bits (679), Expect = 9e-73
Identities = 215/660 (32%), Positives = 341/660 (51%), Gaps = 74/660 (11%)
Query: 20 RCQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYR 79
R + L++DF + ++I H PE+ TL VSF D+E Y++ A +I+
Sbjct: 10 RIKDLWRDFFRTYGYSDKIN-SIHQDY---PEVRTLYVSFKDIEDYDRQFAASILASP-E 64
Query: 80 IYPFLNRAIL--NYILSLAETGMK------KDLQDKECYVSFVDVPTRHKVRELTTAKIG 131
IY I+ +Y+L + KDL+D+ T + +R++ +A IG
Sbjct: 65 IYLKTGEEIVMEDYLLDKVSRRFRIFHLRIKDLEDRN---------TSYNIRDIRSANIG 115
Query: 132 TLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQ 191
TLI +SG + + V P+L F N V N R + + + +++
Sbjct: 116 TLISVSGIVRKNTEVFPKLKNAAFECSNCHELNYVEQNESRL---TEPLYCANCGQSKVK 172
Query: 192 ETQAELPRGCIPRSLEV--ILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEIT 249
+ + R + ++V I E E+++ G + +IV D+ L PG+R +
Sbjct: 173 DKISFKLRPNLSEFIDVQKIEIQEDPETLEGGAQPQRL-IIIVEDDLAGLLFPGNRVVV- 230
Query: 250 TRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRK 309
+GI L+A R+ + + AV+ R E+ + +T ED K
Sbjct: 231 -----------DGI--LQAEQRRQGNVPLTEFYTFLYAVNIRKDVKEIESVKITEED--K 275
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
Q K+ E+S+ N+ + + S+ P+IHG + +K+ + L +FGGV KT +GTT+R
Sbjct: 276 Q-------KIIEISKRPNVIDVIAKSIAPTIHGLDMIKKALALQMFGGVRKTMKDGTTMR 328
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD-FVIEA 428
GDI++ +VGDP TAKSQLLK ++E++PR ++T G+ SSAAGLTAA VRDE + +EA
Sbjct: 329 GDIHILMVGDPGTAKSQLLKYMAEVSPRGIFTFGRGSSAAGLTAAAVRDEFGEGRWTLEA 388
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPI 488
GAL+LADNG IDE DKMD D A+HEAMEQQT++++KAG+ ATL AR S+LAAANP
Sbjct: 389 GALVLADNGFVAIDELDKMDEHDTAAMHEAMEQQTVTISKAGIMATLRARASVLAAANPK 448
Query: 489 GGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH---------- 538
GRYD ++L + + P++SRFD+ F ++D+ ++ D +A ++ H
Sbjct: 449 FGRYDLNRNLAEQINFPLPLLSRFDVIFKMVDQPNKDTDSQLAEHVLKAHRLGEIYKSME 508
Query: 539 -------CNKEESYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXX 590
E Y+ +D L +Y+A+A++ P +++EA +L + Y
Sbjct: 509 KNDIEIDVPDEAKYEPDIDKDLLRKYVAYAKNNVFPRLSDEAIAILQDQYVRTRTGSRDS 568
Query: 591 XXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDED 650
ITVRQLES +RLAE A+ S VT A ++++ + V + +D D
Sbjct: 569 IP----ITVRQLESTIRLAEAAARARLSTIVTVEDAMLAKKIVDYYLTDVSTENGKMDID 624
>UniRef50_Q5CJF4 Cluster: DNA replication licensing factor mcm5;
n=2; Cryptosporidium|Rep: DNA replication licensing
factor mcm5 - Cryptosporidium hominis
Length = 793
Score = 276 bits (677), Expect = 1e-72
Identities = 187/531 (35%), Positives = 280/531 (52%), Gaps = 50/531 (9%)
Query: 152 QGTFYTIPTICRNPVCANRRRFMLD-----ADKSVFVDFQKIRIQETQAELPRGCIPRSL 206
QGT +P +C + + LD D+S ++D Q ++ QE +P G IPR++
Sbjct: 237 QGTM--LPRVCNTTPIGDAPKCPLDPYFTLCDESEYIDIQSMKFQELPEHVPTGDIPRNI 294
Query: 207 EVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGL 266
+ + ++ V G+R L VV + + S+A ++R G + L
Sbjct: 295 SLHMTRGLIDKVIPGNR------LYVVGVLSSTDKESSKAHSSSRN-----GSLR-TSYL 342
Query: 267 KALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDR 326
+GV ++Y +++ S + + + + E+ R+ +S
Sbjct: 343 HVIGV--MNYGSSW---SNKNTNTLIKNSSISNQYNEIEEFRR------------ISSLP 385
Query: 327 NLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQ 386
N++ ++ S+ P+I+GN +K+ + +LF G +K +G +RGD+NV ++GDPSTAKSQ
Sbjct: 386 NIHELIVNSIAPAIYGNETIKQAIACLLFSGSSKCLPDGNRIRGDLNVLLLGDPSTAKSQ 445
Query: 387 LLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDK 446
LLK V ++ P +YTSGK SSAAGLTAA+V+D + + +E GA++LAD GV CIDEFDK
Sbjct: 446 LLKFVEQVAPICIYTSGKGSSAAGLTAAIVKDHANGVYALEGGAMVLADGGVVCIDEFDK 505
Query: 447 MDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSP 506
M D+VAIHEAMEQQTIS+AKAG+ L AR SILAAANP G YD +K L Q
Sbjct: 506 MRDDDRVAIHEAMEQQTISIAKAGITTILKARCSILAAANPTFGSYDDSKDLTQQHDFES 565
Query: 507 PIMSRFDLFFILIDESSEMVDYAIARKIVDLH--CNKEESYDCVYSR-----DDLLRYIA 559
I+SRFDL F+L DE + D IA IV+LH + S DC S + L +YI
Sbjct: 566 TILSRFDLIFLLKDEKNVERDKLIASHIVELHSGIKGKMSGDCSESTNSLQFEQLQKYIN 625
Query: 560 FARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWR------ITVRQLESMVRLAEGV 612
+ R F P ++ +A +L +Y + ITVRQLE++ R+AE
Sbjct: 626 YCREFIHPRLSLDAAAILENFYVKIREDNREDTNKASKDRIPIPITVRQLEAITRIAESF 685
Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQD 663
AKM + HV A +L + I + +I L ++ E S +D +
Sbjct: 686 AKMEMQNIASEKHVEMAIKLFKNATIEAIKSNILLLDNLSPTEQSAIIDAE 736
>UniRef50_Q54RU0 Cluster: MCM family protein; n=1; Dictyostelium
discoideum AX4|Rep: MCM family protein - Dictyostelium
discoideum AX4
Length = 789
Score = 276 bits (676), Expect = 2e-72
Identities = 138/337 (40%), Positives = 213/337 (63%), Gaps = 6/337 (1%)
Query: 300 HDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVA 359
H T E + +T++ K+ + S++ N+Y+ L SL P I+G+ +VK+ +LLM+ GG +
Sbjct: 377 HKKTYEQL--DLTEEMLKKIQDESQNENIYDRLAMSLAPEIYGHLDVKKALLLMMVGGES 434
Query: 360 KTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE 419
K +G +RGDIN+C++GDP AKSQLLK ++++ PR +YTSGK SS GLTAAV+RD
Sbjct: 435 KHMKDGMNIRGDINICLMGDPGIAKSQLLKHIAKVAPRGIYTSGKGSSGVGLTAAVIRDT 494
Query: 420 ESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNART 479
+ +FV+E G+L+LAD G+CCIDEFDKM+ D+ AIHE MEQQTIS+AKAG+ TLNART
Sbjct: 495 MTGEFVLEGGSLVLADMGICCIDEFDKMEDSDRTAIHEVMEQQTISIAKAGITTTLNART 554
Query: 480 SILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC 539
SILAAANP GRY+ +S +N L ++SRFDL F+++D++ D ++ + +H
Sbjct: 555 SILAAANPAYGRYNFDRSPDENFRLPHSLLSRFDLLFLMVDKADMDNDRLLSEHVTYVHM 614
Query: 540 NKEE---SYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWR 596
+ + S++ + + + Y++ AR P + ++ +V+ Y
Sbjct: 615 HSKPPQLSFE-PFDSEFIRAYVSQARKIIPPVPKDLTNYIVDSYITLRKQDSETKTPFTY 673
Query: 597 ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
T R L ++RL++ A++ S V+ V E+ RL+
Sbjct: 674 TTARTLLGVLRLSQAFARLKFSQQVSQEDVEESMRLM 710
Score = 44.4 bits (100), Expect = 0.012
Identities = 21/58 (36%), Positives = 31/58 (53%)
Query: 180 SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVG 237
S FV FQ+I++QE ++P G PRS++V +R E GD +G + P G
Sbjct: 298 SKFVKFQEIKVQEIANQVPIGHTPRSIKVYVRGELTRMASPGDIVTMSGIFLPTPYTG 355
>UniRef50_A2DCM5 Cluster: MCM2/3/5 family protein; n=1; Trichomonas
vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas
vaginalis G3
Length = 752
Score = 276 bits (676), Expect = 2e-72
Identities = 209/634 (32%), Positives = 321/634 (50%), Gaps = 67/634 (10%)
Query: 26 QDFLEEFK-EDNEIK--YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYP 82
+ F+ +FK ++NE + Y +E+ + L V V K+ ++L I+ +
Sbjct: 64 RSFVTKFKLDENEEEGLYFTKIREMNVIQEYNLNVDMQHVFKHQESLYHQIVAFPLEMIQ 123
Query: 83 FLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVR 142
+ +++ + T + + E V ++ +REL I L+ + G I R
Sbjct: 124 IFD-SVIKEMFQAINTADNEHVN--EVQVRPYNLLETKSIRELHPTDIDRLVSVRGMITR 180
Query: 143 THPVHPELVQGTF--------YTIP-------TICRNPVCANRRRFMLDADKSVFVDFQK 187
+ PV P+L Q TF ++P T + P C ++ + S+F D Q
Sbjct: 181 SSPVIPDLSQATFRCRACKHVLSVPVANGKVETPAQCPGCKKNDTLEMEHNLSIFTDRQH 240
Query: 188 IRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAE 247
I++QE S E I + E ++V A IV ++ + PG R
Sbjct: 241 IKLQE------------SPETIPQGETPQTVGA----------IVFEELVDYAKPGDRVI 278
Query: 248 ITTRTKLANEGQMEGIKGLKALGVRELH--YKTAFLACSVQA-VSRRFGTAELPTHDLTT 304
+T G + VR LH Y+T ++ + R +L + T
Sbjct: 279 LT--------GIWRAMPARINPRVRTLHSVYRTYIDVVHIKKNLDRAIENEDLNGFNEAT 330
Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364
++ KE D+ +S+D +Y+ LI S PSI E K+G+L +LFGG T
Sbjct: 331 LTAAQKKA-KE-DRCIVLSKDPEIYDKLIKSFAPSIWEMEEQKKGLLCLLFGGAVSKT-- 386
Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDF 424
RGDIN+ +VGDP+TAKSQL++ +I PR +YTSGK SSA GLTA+VVRD ES +F
Sbjct: 387 ----RGDINILLVGDPATAKSQLIQYTHKIAPRGLYTSGKGSSAVGLTASVVRDTESGEF 442
Query: 425 VIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAA 484
V+E+GAL+L+D GVCCIDEFDKMD + +HE MEQQTIS+AKAG+ +LNAR +I+A
Sbjct: 443 VLESGALVLSDRGVCCIDEFDKMDDSARSVLHEVMEQQTISIAKAGIVTSLNARAAIVAC 502
Query: 485 ANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544
ANP Y+ S+ +N+ L P ++SRFDL ++++D SE+ D +AR I+ L+ ++E
Sbjct: 503 ANPRDSSYNSKLSVVENIQLPPTLLSRFDLIYLVLDHVSEIRDQQLARHIIGLYTTRDE- 561
Query: 545 YDCVYSRDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLE 603
L YIA+A+ + P++T++A K L + Y T RQL+
Sbjct: 562 LSTPIPPQQLSEYIAYAKENCLPMLTDKAAKRLEQGYIDMRNAGGKNVISA---TTRQLQ 618
Query: 604 SMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
S +R+AE AKM S V V A L+ +++
Sbjct: 619 SCIRIAEAWAKMRLSEIVEEKDVDVALDLMKEAL 652
>UniRef50_P33992 Cluster: DNA replication licensing factor MCM5;
n=51; Eukaryota|Rep: DNA replication licensing factor
MCM5 - Homo sapiens (Human)
Length = 734
Score = 275 bits (675), Expect = 3e-72
Identities = 212/676 (31%), Positives = 333/676 (49%), Gaps = 86/676 (12%)
Query: 5 DTYATQSQVKDEVGIRCQKLFQDFLEEFKEDNE-----IKYEKHAKELLKPELSTLEVSF 59
D A + Q + + Q+ F++FL +++ + KY K +EV
Sbjct: 18 DAQADEGQARKS---QLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEM 74
Query: 60 DDVEKYNQNLATTIIE---EYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDV 116
+D+ ++++LA + + E+ ++ + + + + +G ++ LQD + +
Sbjct: 75 EDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSG-EEVLQDIQVMLKSDAS 133
Query: 117 PTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF--------------------Y 156
P+ +R L + + L++I G I+ V + + + Y
Sbjct: 134 PS--SIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGY 191
Query: 157 TIPTICRNPVCANRRRFMLDA-----DKSVFVDFQKIRIQETQAELPRGCIPRSLEVILR 211
+P C N A R + LD DK VDFQ +++QE +P G +PR +++
Sbjct: 192 ALPRKC-NTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCD 250
Query: 212 AEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGV 271
+ V G+R T++ + + + SR R ++ +G+
Sbjct: 251 RYLCDKVVPGNRV----TIMGIYSIKKFGLTTSRG----RDRVG-------------VGI 289
Query: 272 RELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331
R + + + R F A P + E+ R+ ++ N+Y
Sbjct: 290 RSSYIRVLGIQVDTDGSGRSFAGAVSPQEE---EEFRR------------LAALPNVYEV 334
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391
+ S+ PSI G ++K+ + +LFGG K +G T RGDIN+ ++GDP TAKSQLLK V
Sbjct: 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFV 394
Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451
+ +P VYTSGK SSAAGLTA+V+RD S +F++E GA++LAD GV CIDEFDKM D
Sbjct: 395 EKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDD 454
Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511
+VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+D K + N+ P I+SR
Sbjct: 455 RVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSR 513
Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL---RYIAFAR-SFKPV 567
FD+ FI+ DE +E D +A+ ++ LH + V DL ++IA+ R P
Sbjct: 514 FDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPR 573
Query: 568 ITEEAGKLLVEYYXXXXXXXXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHCSGHVT 622
++ EA + L Y R ITVRQLE++VR+AE ++KM T
Sbjct: 574 LSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFAT 633
Query: 623 PAHVHEAYRLLNKSII 638
A V EA RL S +
Sbjct: 634 EADVEEALRLFQVSTL 649
>UniRef50_P30666 Cluster: DNA replication licensing factor mcm3;
n=10; Fungi/Metazoa group|Rep: DNA replication licensing
factor mcm3 - Schizosaccharomyces pombe (Fission yeast)
Length = 879
Score = 275 bits (675), Expect = 3e-72
Identities = 190/549 (34%), Positives = 289/549 (52%), Gaps = 64/549 (11%)
Query: 15 DEVGIRCQKLFQDFLEEFKED-NEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT-T 72
DEV ++FQ++LE +D N Y++ +L L V+ D++ YN+ LA
Sbjct: 7 DEVFKDRVRIFQEYLEHDTDDANVTLYQEAILRMLNMGQRRLIVNIDELRDYNRELADGV 66
Query: 73 IIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKV--RELTTAKI 130
+++ + PF + A+ N + +L + + KDL+DK YV F H V R L +
Sbjct: 67 LLKPLEYVEPF-DEALRNVVSTLIDPVVHKDLKDKLFYVGFRGSFGDHHVNPRTLRAMHL 125
Query: 131 GTLIRISGQIVRTHPVHPELVQGTF------------YTIPTI-----CRNPVCA----N 169
+I + G + R V P++++ Y T+ ++ V N
Sbjct: 126 NKMISLEGIVTRCSFVRPKVIKSVHYCEATKRHHFKQYADATMNGGLSFQSTVYPTQDEN 185
Query: 170 RRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229
++ S F D Q I +QE P G +PRS++++L + V++V+
Sbjct: 186 GNPLSIEFGFSTFRDHQSISLQEMPERAPPGQLPRSIDILLDDDLVDTVK---------- 235
Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289
PG R I GQ + G K G ++T LA +V +
Sbjct: 236 ------------PGDRVNIV--------GQYRSM-GSKTSGNTSATFRTVLLANNVVLLG 274
Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349
+ G + L +TD + + +++R +N++ L TSL PSI+G VK+
Sbjct: 275 NKPGLGNVGGGAL-------DITDADIRNINKLARKKNVFELLSTSLAPSIYGYEYVKQA 327
Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409
+LL+L GG K GT +RGDIN+ +VGDPSTAKSQLL+ V P A+ T+G+ SS
Sbjct: 328 ILLLLLGGTEKNLTNGTHIRGDINILMVGDPSTAKSQLLRFVLNTAPLAIATTGRGSSGV 387
Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469
GLTAAV D+E+ + +EAGA++LAD GV CIDEFDKM D+VAIHE MEQQT+++AKA
Sbjct: 388 GLTAAVTTDKETGERRLEAGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKA 447
Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529
G+ +LNAR S++AAANPI G+YD K QN+AL ++SRFDL FI+ D+ + D A
Sbjct: 448 GIHTSLNARCSVIAAANPIYGQYDIRKDPHQNIALPDSMLSRFDLLFIVTDDIDDKKDRA 507
Query: 530 IARKIVDLH 538
++ ++ +H
Sbjct: 508 LSEHVLRMH 516
>UniRef50_UPI00015BB272 Cluster: replicative DNA helicase Mcm; n=1;
Ignicoccus hospitalis KIN4/I|Rep: replicative DNA
helicase Mcm - Ignicoccus hospitalis KIN4/I
Length = 689
Score = 275 bits (674), Expect = 3e-72
Identities = 144/324 (44%), Positives = 212/324 (65%), Gaps = 2/324 (0%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRG 370
++ ++ +++ E+S+D ++ ++I S+ P+I+G+ ++K + LFGGV K +GT +RG
Sbjct: 273 LSPEDVERIKELSKDPWIHKSIILSIAPAIYGHWDIKEAIAFALFGGVPKELEDGTRIRG 332
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGA 430
DI+V I+GDP TAKSQLL+ + I PR+VYT+GK S+AAGLTAAVVRD + ++ +EAGA
Sbjct: 333 DIHVLIIGDPGTAKSQLLQYAARIAPRSVYTTGKGSTAAGLTAAVVRDNITGEYYLEAGA 392
Query: 431 LMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGG 490
L+LAD GV IDE DKM D+ AIHEAMEQQT+S+AKAG+ A LNAR ++LAA NP G
Sbjct: 393 LVLADGGVAVIDEIDKMREEDRSAIHEAMEQQTVSIAKAGIVAKLNARCAVLAAGNPRYG 452
Query: 491 RYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYS 550
RY +S+ +N+ L P I+SRFDL F+L D D + R I+++H ++ +
Sbjct: 453 RYVPERSVAENINLPPSILSRFDLIFVLRDVPDPKRDRRLVRYILNVHKEADKIVPEI-P 511
Query: 551 RDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLA 609
D L +YIA+AR S KP ++E A +++ ++ IT RQLE++VR++
Sbjct: 512 ADLLKKYIAYARKSVKPKLSEAAARIIENFFVDLRKTAAENPEMGVPITARQLEALVRMS 571
Query: 610 EGVAKMHCSGHVTPAHVHEAYRLL 633
E AKM V A EA R++
Sbjct: 572 EAHAKMALRSVVEEADAIEAVRMM 595
Score = 87.0 bits (206), Expect = 2e-15
Identities = 64/235 (27%), Positives = 116/235 (49%), Gaps = 28/235 (11%)
Query: 22 QKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIY 81
++ F++FLE ++ + +KY+ + + +++ V F DV +++Q LA I+E
Sbjct: 14 EERFREFLESYEVNGRVKYKDEIRNAVAERRASVVVDFTDVIEFDQELAEEIVENPLETL 73
Query: 82 PFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQI- 140
L++ + ++ A K ++ V F ++P + ++R+L +G L+ G +
Sbjct: 74 DKLDQVVTE--IASAFANKKYPMR-----VRFTNLPEKVRLRDLRERYVGKLVAFDGIVT 126
Query: 141 ----VRTHP------------VHPELVQGTFYTIPTICRNPVCANRRR-FML--DADKSV 181
V+ P V P +G +Y PT+C NP C + F L + K+
Sbjct: 127 KATNVKGKPKKLYFRCEACGTVFPVEQRGKYYQAPTVCPNPECPKKTGPFTLLENHPKNE 186
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRA-EAVESVQAGDRYDFTGTLIVVPD 235
+VD+Q + +QE ELP G +PRS+EVI+ + V+ + GDR G L VP+
Sbjct: 187 YVDWQLLVVQEKPEELPPGQMPRSIEVIVEGKDLVDVARPGDRVTVIGVLEAVPN 241
>UniRef50_A0BS22 Cluster: Chromosome undetermined scaffold_124,
whole genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_124,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 732
Score = 275 bits (674), Expect = 3e-72
Identities = 150/331 (45%), Positives = 203/331 (61%), Gaps = 16/331 (4%)
Query: 322 MSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPS 381
+SR+R++Y + S+ P+I+G+ ++K + +LFGG +K + LRGDINV ++GDPS
Sbjct: 316 LSRNRDVYKIITNSIAPAIYGHEDIKLAIACLLFGGTSKNLPDSMKLRGDINVLLIGDPS 375
Query: 382 TAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCI 441
TAKSQLLK V +VYTSGK SSAAGLTA + + F +EAGAL+LA GVCCI
Sbjct: 376 TAKSQLLKFVERAADISVYTSGKGSSAAGLTATITYQHNTSQFTLEAGALVLASGGVCCI 435
Query: 442 DEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQN 501
DEFDKM D+VA+HEAMEQQTIS+AKAG+ LNA+ SILAAANPI GRY KS+Q+
Sbjct: 436 DEFDKMRSEDRVAMHEAMEQQTISIAKAGITTRLNAKCSILAAANPIFGRYQENKSIQEQ 495
Query: 502 VALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDD-------- 553
+ L I+SRFD FI+ D S D +A I+ LH + + + D
Sbjct: 496 IELQTTILSRFDNIFIIRDVRSIENDQRLANHIISLHTGQFADQEGMQIEQDSNNSMDLM 555
Query: 554 -LLRYIAFARSF-KPVITEEAGKLLVEYY------XXXXXXXXXXXXXXWRITVRQLESM 605
L +YI +A+S KP++TE+A +++ Y ITVRQLE++
Sbjct: 556 KLKQYIKYAKSIVKPLLTEQAAQMIQNLYVDDRQISQQPHHSKSGGKSHIPITVRQLEAI 615
Query: 606 VRLAEGVAKMHCSGHVTPAHVHEAYRLLNKS 636
+R++E +AKM HV HV EA+RL S
Sbjct: 616 IRISESLAKMQLLEHVKEEHVKEAHRLFQIS 646
Score = 36.3 bits (80), Expect = 3.2
Identities = 19/62 (30%), Positives = 30/62 (48%)
Query: 173 FMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIV 232
+++ ++ F+D Q +RIQE +P G +PR+ V V + G R TG V
Sbjct: 208 YVIIPEECQFIDQQTLRIQELSEAIPTGEVPRNFMVYCDRYLVNKLIPGQRVIITGVYQV 267
Query: 233 VP 234
P
Sbjct: 268 PP 269
>UniRef50_Q9YFR1 Cluster: Minichromosome maintenance protein; n=2;
Desulfurococcales|Rep: Minichromosome maintenance
protein - Aeropyrum pernix
Length = 697
Score = 274 bits (671), Expect = 8e-72
Identities = 146/328 (44%), Positives = 206/328 (62%), Gaps = 6/328 (1%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRG 370
+T ++ +K+ ++SRD + +I S+ P+I+G+ ++K + L+LFGGV K +GT RG
Sbjct: 274 ITREDEEKILQLSRDPWIKEKIIASIAPTIYGHWDLKEAIALLLFGGVPKQRPDGTRTRG 333
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGA 430
DI+V VGDP AKSQLL+ +++ PR VYT+GK S+AAGLTAAV+RD + ++ +EAGA
Sbjct: 334 DIHVLFVGDPGVAKSQLLQSTAQVAPRVVYTTGKGSTAAGLTAAVLRDPRTGEYFLEAGA 393
Query: 431 LMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGG 490
L+LAD G+ IDEFDKM D+ IHEAMEQQT+S+AKAG++ATL+AR S+LAA NP G
Sbjct: 394 LVLADGGIAVIDEFDKMSKEDRGVIHEAMEQQTVSIAKAGIKATLSARASLLAAGNPKFG 453
Query: 491 RYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYS 550
YD ++S NV L PI+SRFDL F++ D D +A +++ H N E +
Sbjct: 454 YYDPSRSFVDNVDLPAPIISRFDLIFVVRDVIERSRDEMLASYVLETHTN-VELFKPEID 512
Query: 551 RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWR----ITVRQLESM 605
D L +YIAFAR KP +T +A KLL ++Y IT RQLE++
Sbjct: 513 PDLLRKYIAFARKHVKPRLTPQAKKLLKDFYVEMRSSALHHSSQEGAKPVPITTRQLEAL 572
Query: 606 VRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
+RL E A+M T A R++
Sbjct: 573 IRLTEAHARMSLKQEATEEDAIAAIRIM 600
Score = 87.4 bits (207), Expect = 1e-15
Identities = 63/230 (27%), Positives = 113/230 (49%), Gaps = 30/230 (13%)
Query: 25 FQDFLEEFK-EDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83
F+ FLE F+ E+ ++KY + + ++ E ++LEV F D+ +Y+ L+ ++E+
Sbjct: 18 FKTFLENFRTEEGKLKYVEAIRRMINYEETSLEVEFKDLYRYDPLLSEILLEKPREFLKE 77
Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143
+ A+ + + + Q + F + ++R++ + +G L++I+G + R
Sbjct: 78 ASEALKEIVAQESP----EYAQGRVFTPRFTGLFDTERIRDIGSDHVGKLVQINGIVTRM 133
Query: 144 HPVHPELVQGTF----------------------YTIPTICRNPVCANRR-RFMLDADKS 180
HP +V+ F P+IC PVC +F L DKS
Sbjct: 134 HPRATRMVRARFRHDRCGAEFWWPANEDEVLGERIERPSIC--PVCGEGGGKFTLVRDKS 191
Query: 181 VFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTL 230
+++D+QKI +QE ++P G IPRS+EV L + VE V+ GDR G +
Sbjct: 192 LYIDWQKIMVQERPEDVPGGQIPRSIEVHLSRDLVEKVRPGDRVKIVGVV 241
>UniRef50_P43299 Cluster: Protein PROLIFERA; n=10; Eukaryota|Rep:
Protein PROLIFERA - Arabidopsis thaliana (Mouse-ear
cress)
Length = 716
Score = 273 bits (670), Expect = 1e-71
Identities = 144/370 (38%), Positives = 221/370 (59%), Gaps = 5/370 (1%)
Query: 278 TAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLF 337
T F A V+ + A TH + + D+E +++ ++ D ++YN L SL
Sbjct: 277 TGFKALRAGLVADTYLEATSVTHFKKKYEEYEFQKDEE-EQIARLAEDGDIYNKLSRSLA 335
Query: 338 PSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPR 397
P I+G+ ++K+ +LL+L G + +G +RGD+++C++GDP AKSQLLK + + PR
Sbjct: 336 PEIYGHEDIKKALLLLLVGAPHRQLKDGMKIRGDVHICLMGDPGVAKSQLLKHIINVAPR 395
Query: 398 AVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHE 457
VYT+GK SS GLTAAV+RD+ + + V+E GAL+LAD G+C IDEFDKMD D+ AIHE
Sbjct: 396 GVYTTGKGSSGVGLTAAVMRDQVTNEMVLEGGALVLADMGICAIDEFDKMDESDRTAIHE 455
Query: 458 AMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFI 517
MEQQT+S+AKAG+ +LNART++LAAANP GRYD ++ +N+ L P ++SRFDL ++
Sbjct: 456 VMEQQTVSIAKAGITTSLNARTAVLAAANPAWGRYDLRRTPAENINLPPALLSRFDLLWL 515
Query: 518 LIDESSEMVDYAIARKIVDLHCNKEESYDCVYS--RDDLLR-YIAFARSFKPVITEEAGK 574
++D + D +A+ ++ +H EES + ++LR YI+ AR P + E +
Sbjct: 516 ILDRADMDSDLELAKHVLHVH-QTEESPALGFEPLEPNILRAYISAARRLSPYVPAELEE 574
Query: 575 LLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN 634
+ Y TVR L S++R++ +A++ S V + V EA RL+
Sbjct: 575 YIATAYSSIRQEEAKSNTPHSYTTVRTLLSILRISAALARLRFSESVAQSDVDEALRLMQ 634
Query: 635 KSIIRVEQPD 644
S I + D
Sbjct: 635 MSKISLYADD 644
Score = 54.4 bits (125), Expect = 1e-05
Identities = 45/155 (29%), Positives = 70/155 (45%), Gaps = 25/155 (16%)
Query: 107 KECYVSFVDVPTRHK---VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYT------ 157
K Y + P++ + +RE+ + IG L+RISG + R V P L+ YT
Sbjct: 125 KRYYEVYFKAPSKGRPSTIREVKASHIGQLVRISGIVTRCSDVKP-LMAVAVYTCEDCGH 183
Query: 158 -----------IPTI-CRNPVCANRRRF---MLDADKSVFVDFQKIRIQETQAELPRGCI 202
+P C + C + +L S F+ FQ+ ++QE +P+G I
Sbjct: 184 EIYQEVTSRVFMPLFKCPSSRCRLNSKAGNPILQLRASKFLKFQEAKMQELAEHVPKGHI 243
Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVG 237
PRS+ V LR E V GD +F+G + +P G
Sbjct: 244 PRSMTVHLRGELTRKVSPGDVVEFSGIFLPIPYTG 278
>UniRef50_P38132 Cluster: DNA replication licensing factor CDC47;
n=21; Eukaryota|Rep: DNA replication licensing factor
CDC47 - Saccharomyces cerevisiae (Baker's yeast)
Length = 845
Score = 272 bits (667), Expect = 2e-71
Identities = 183/509 (35%), Positives = 272/509 (53%), Gaps = 51/509 (10%)
Query: 151 VQGTFYTIPTICRNPVCANRR---RFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLE 207
V +T + C + C+ + + + S F FQ+ +IQE ++P G IPRSL
Sbjct: 273 VNSRTFTPLSECTSEECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLN 332
Query: 208 VILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLK 267
+ + GTL V +LS PG ++T + G K LK
Sbjct: 333 IHVN----------------GTL-----VRSLS-PGDIVDVTG---IFLPAPYTGFKALK 367
Query: 268 ALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRN 327
A + E + + F V+ ++F + L T D+ ++V E+ +
Sbjct: 368 AGLLTETYLEAQF----VRQHKKKFASFSL------TSDVE--------ERVMELITSGD 409
Query: 328 LYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQL 387
+YN L S+ P I+GN +VK+ +LL+L GGV K +G +RGDINVC++GDP AKSQL
Sbjct: 410 VYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQL 469
Query: 388 LKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKM 447
LK + +I+PR VYT+GK SS GLTAAV++D + + ++E GAL+LADNG+CCIDEFDKM
Sbjct: 470 LKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKM 529
Query: 448 DPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPP 507
D D+ AIHE MEQQTIS++KA + ARTSILAAANP+ GR + S N+ L
Sbjct: 530 DESDRTAIHEVMEQQTISISKAVINTNPGARTSILAAANPLYGRINPRLSPLDNINLPAA 589
Query: 508 IMSRFDLFFILIDESSEMVDYAIARKIVDLHC-NKEESYDCVYSRDDLLR-YIAFARSFK 565
++SRFD+ F+++D S D +A + +H NK+ D +R YIA+A++ +
Sbjct: 590 LLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKR 649
Query: 566 PVITEEAGKLLVEYYXXXXXXXXXXXXXXW---RITVRQLESMVRLAEGVAKMHCSGHVT 622
PV++E +V+ Y + + T R L ++RL++ +AK+ + V
Sbjct: 650 PVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVD 709
Query: 623 PAHVHEAYRLLNKSIIRVEQPDIHLDEDE 651
V EA RL+ S + Q EDE
Sbjct: 710 IDDVEEALRLVRVSKESLYQETNKSKEDE 738
>UniRef50_Q2NHD8 Cluster: Predicted minichromosome maintenance
protein; n=3; Methanobacteriaceae|Rep: Predicted
minichromosome maintenance protein - Methanosphaera
stadtmanae (strain DSM 3091)
Length = 670
Score = 271 bits (664), Expect = 6e-71
Identities = 142/321 (44%), Positives = 206/321 (64%), Gaps = 5/321 (1%)
Query: 313 DKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDI 372
+++ +K+ E+++ ++Y +I S PSI G EVK + LFGG AK + T +RGD+
Sbjct: 258 EEDEEKIIELAKSPDIYQKIIESTAPSIRGYFEVKEAIAFQLFGGTAKVLEDKTHIRGDM 317
Query: 373 NVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALM 432
++ IVGDP KSQ+LK VS++ PR +YTSGK +S GLTAA VRD+ + +EAGAL+
Sbjct: 318 HILIVGDPGIGKSQILKYVSKLAPRGIYTSGKGTSGVGLTAAAVRDDLG-GWSLEAGALV 376
Query: 433 LADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRY 492
L D G C+DE DKM D+ AIHEA+EQQTIS+AKAG+ ATLN+R S+LAAANP GR+
Sbjct: 377 LGDKGNVCVDELDKMREEDRSAIHEALEQQTISIAKAGIMATLNSRCSVLAAANPKFGRF 436
Query: 493 DRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRD 552
DR KS+ + + L PI+SRFDL FI+ D+ + D+ +A I+ +H ++ + V +
Sbjct: 437 DRYKSIAEQIDLPSPILSRFDLIFIIEDKPNAERDHDLAGHILKIH--QDSTIPYVIEPE 494
Query: 553 DLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEG 611
+ +YIA+AR S +P +T+EA ++L ++Y IT RQLE++VRLAE
Sbjct: 495 LMRKYIAYARKSVQPTLTKEAAEVLQDFYVTMRSGAIDEESPV-PITARQLEALVRLAEA 553
Query: 612 VAKMHCSGHVTPAHVHEAYRL 632
A++ S V A +L
Sbjct: 554 SARIRLSNEVLKEDAQRAIKL 574
Score = 59.3 bits (137), Expect = 4e-07
Identities = 55/216 (25%), Positives = 98/216 (45%), Gaps = 24/216 (11%)
Query: 29 LEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAI 88
LEEF K E A + PE ++ V ++++E ++ + A +IE+ ++I
Sbjct: 19 LEEFFS-TRCKDEVFAVLDMFPEEKSVVVDYNELEMFDPDSADLLIEKPDETLEAATKSI 77
Query: 89 LNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHP 148
+N + ++ + V F +V +R L + IG I + G + +T +HP
Sbjct: 78 VN---------IDPQRKNAKLNVRFKNVRNNIPLRFLRSEFIGKFIAVDGIVRKTDEIHP 128
Query: 149 ELVQGTF--------YTIP---TICRNP-VC--ANRRRFMLDADKSVFVDFQKIRIQETQ 194
++ F + + I P VC R F L D+S ++D Q +++QE
Sbjct: 129 RIMSAVFECRSCMRMHEVEQKSNIIHEPAVCQECGGRSFRLVQDESRYMDTQTVKLQEPL 188
Query: 195 AELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTL 230
L G PR + +IL + V+++ GD+ TGTL
Sbjct: 189 ENLSGGDQPRQINIILEDDLVDTLAPGDKVRITGTL 224
>UniRef50_P25205 Cluster: DNA replication licensing factor MCM3;
n=64; Eumetazoa|Rep: DNA replication licensing factor
MCM3 - Homo sapiens (Human)
Length = 808
Score = 270 bits (661), Expect = 1e-70
Identities = 184/549 (33%), Positives = 296/549 (53%), Gaps = 72/549 (13%)
Query: 13 VKDEVGIR-CQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71
V D+V +R Q+ + DFL++ +ED I Y+ +EL+ L V+ +D+ + N+ A
Sbjct: 6 VLDDVELREAQRDYLDFLDD-EEDQGI-YQSKVRELISDNQYRLIVNVNDLRRKNEKRAN 63
Query: 72 TIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFV-DVPTRH-KVRELTTAK 129
++ + RA+ +++ S+ T K Q +E YV ++H R LT+
Sbjct: 64 RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120
Query: 130 IGTLIRISGQIVRTHPVHPELVQGTFYT-------------IPTICRNPVCA-----NRR 171
+ ++ + G + + V P++V+ Y + T+ P + +
Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180
Query: 172 RFMLDADK--SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229
L+ + SV+ D Q I IQE + P G +PRS++VIL + V+ + GDR GT
Sbjct: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT 240
Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289
+PG + T+ T ++T +AC+V+ +S
Sbjct: 241 Y--------RCLPGKKGGYTSGT-----------------------FRTVLIACNVKQMS 269
Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349
+ A+ P+ + ED+ K K + +R +++++ L SL PSIHG++ VK+
Sbjct: 270 K---DAQ-PS--FSAEDIAKI-------KKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKA 316
Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409
+L +L GGV + G+ +RGDIN+ ++GDPS AKSQLL+ V PRA+ T+G+ SS
Sbjct: 317 ILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376
Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469
GLTAAV D+E+ + +EAGA++LAD GV CIDEFDKM D+ AIHE MEQ +++AKA
Sbjct: 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKA 436
Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529
G+ A LNAR S+LAAANP+ GRYD+ K+ +N+ L ++SRFDL FI++D+ D
Sbjct: 437 GIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDRE 496
Query: 530 IARKIVDLH 538
I+ ++ +H
Sbjct: 497 ISDHVLRMH 505
Score = 45.6 bits (103), Expect = 0.005
Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 7/134 (5%)
Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYX--XXXXXXXXXXXXX 594
LH K++ V S + +YI A+ KPV+T+E+ + E Y
Sbjct: 552 LHGTKKKKEKMV-SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART 610
Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN----KSIIRVEQPDIHLDED 650
+T R LE+++RLA AK S V EA L+ K ++ E+ ED
Sbjct: 611 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED 670
Query: 651 EPQCEPSMDVDQDE 664
E + E + Q++
Sbjct: 671 ESETEDEEEKSQED 684
>UniRef50_A7AU57 Cluster: DNA replication licensing factor MCM4;
n=1; Babesia bovis|Rep: DNA replication licensing factor
MCM4 - Babesia bovis
Length = 854
Score = 269 bits (659), Expect = 2e-70
Identities = 136/316 (43%), Positives = 206/316 (65%), Gaps = 6/316 (1%)
Query: 319 VYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVG 378
+ +S+ N+Y+ L+ S PSI G+ ++KRG+L LFG + + + +R INV + G
Sbjct: 442 ILHLSKSPNIYDLLVKSFAPSIQGHEDIKRGLLCQLFGA---SVDKNSRMRSQINVLLCG 498
Query: 379 DPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGV 438
DPST+KSQ+L+ V + PR VYTSGK SS GLTA V +D E+ ++V+E+GA++L+D G+
Sbjct: 499 DPSTSKSQMLRYVHMLAPRGVYTSGKGSSQVGLTAYVRKDVETHEYVLESGAVVLSDGGI 558
Query: 439 CCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSL 498
CCIDEFDKMD + +HE MEQQT+++AKAG+ ATLNART+ILA+ANPI RYD++K++
Sbjct: 559 CCIDEFDKMDDFAKSILHEVMEQQTVTIAKAGIVATLNARTAILASANPINSRYDKSKAV 618
Query: 499 QQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYI 558
+N+ L+P + SRFDL ++++D VD AIA+++ + ++ + L RYI
Sbjct: 619 VENINLAPSLFSRFDLIYLVLDCIEPSVDKAIAKRLCNSFAGTDDENPPI-DAVTLSRYI 677
Query: 559 AFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHC 617
+FAR+ P +T E+ +++V Y T RQLE ++RL++ +AKM
Sbjct: 678 SFARAHCNPYLTPESRQIIVSEYLKLRVSEGYTSKLPC-ATARQLEGLIRLSQALAKMKL 736
Query: 618 SGHVTPAHVHEAYRLL 633
S VT + EA RL+
Sbjct: 737 SPRVTASDAREAARLM 752
>UniRef50_Q5CH83 Cluster: Minichromosome maintenance protein mcm7p;
n=2; Cryptosporidium|Rep: Minichromosome maintenance
protein mcm7p - Cryptosporidium hominis
Length = 857
Score = 267 bits (655), Expect = 7e-70
Identities = 153/399 (38%), Positives = 226/399 (56%), Gaps = 25/399 (6%)
Query: 151 VQGTFYTIPTICRNPVCANRRR---FMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLE 207
V+GT Y + C + C N +R + +S F FQ+IRIQE ++P G +PR+++
Sbjct: 223 VEGTNYMPLSDCESSQCKNNKRTGNLKCNIKESKFTKFQEIRIQEPADQVPTGNVPRTMK 282
Query: 208 VILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLK 267
VI E + G +G + V G + R+ +T T I K
Sbjct: 283 VIAMGENTRKLLPGMYVTISGVFLPVVKEGFQAF---RSGLTAETYFEVHNVHSYISN-K 338
Query: 268 ALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRN 327
+ + E K L ++A + R++ + YE+ +
Sbjct: 339 EVSLTEYEKK---LVKQMEADEEKKN--------------REEGLNSSGSGAYEVLHSQ- 380
Query: 328 LYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQL 387
Y+ L S+ P I G +VK+G+LL L GGV +G +RG+I++ ++GDP AKSQL
Sbjct: 381 FYDKLANSIAPEIFGMLDVKKGLLLQLIGGVTNQVNDGMKIRGNIHILLMGDPGVAKSQL 440
Query: 388 LKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKM 447
L Q+++I PR++Y +GK SS GLTA+VVRD+ + + +E GAL+LADNG+CCIDEFDKM
Sbjct: 441 LNQITKIAPRSIYATGKGSSGVGLTASVVRDQNTSEVTLEGGALVLADNGICCIDEFDKM 500
Query: 448 DPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPP 507
D D+ AIHE MEQQT+S+AKAG+ TLNAR+S+LAAANP+ GRYD KS N+ L
Sbjct: 501 DESDRTAIHEVMEQQTVSIAKAGITTTLNARSSVLAAANPVSGRYDPRKSPVANMNLPDS 560
Query: 508 IMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYD 546
++SRFDL F+L+D + D +AR ++ +H N++ D
Sbjct: 561 LLSRFDLQFLLLDIPDKEKDLKLARHVLYVHKNEKAPSD 599
Score = 35.5 bits (78), Expect = 5.7
Identities = 28/108 (25%), Positives = 51/108 (47%), Gaps = 4/108 (3%)
Query: 540 NKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYY-XXXXXXXXXXXXXXWR-- 596
+K + V+S + +I A+++ P++ +E +VE+Y WR
Sbjct: 648 SKSDQEQRVFSTVFMRYFIEKAQTYTPLVPKELVSEIVEHYVELRRREKIEQTREDWRKT 707
Query: 597 -ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQP 643
T R L ++RL++ +A++ S V A EA RL+ +S V +P
Sbjct: 708 YTTPRTLLGILRLSQALARLRFSNIVERADFEEATRLMIESKKSVTKP 755
>UniRef50_Q5KFJ3 Cluster: ATP dependent DNA helicase, putative; n=6;
Dikarya|Rep: ATP dependent DNA helicase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 788
Score = 267 bits (654), Expect = 9e-70
Identities = 139/342 (40%), Positives = 208/342 (60%), Gaps = 5/342 (1%)
Query: 300 HDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVA 359
H L + + T + + + ++ D LY L S+ P I+G+ +VK+ +LL+L GGV
Sbjct: 356 HQLKKQYHAMESTPEIQEAIADLKSDPALYARLANSIAPEIYGHEDVKKALLLLLVGGVT 415
Query: 360 KTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE 419
+ +G +RGDINVC++GDP AKSQLLK ++++ PR VYT+G+ SS GLTAAV+RD
Sbjct: 416 NSRKDGMKIRGDINVCLMGDPGVAKSQLLKYITKVAPRGVYTTGRGSSGVGLTAAVMRDP 475
Query: 420 ESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNART 479
+ + V+E GAL+LADNG+CCIDEFDKM+ D+ AIHE MEQQTIS++KAG+ TLNART
Sbjct: 476 VTDEMVLEGGALVLADNGICCIDEFDKMEESDRTAIHEVMEQQTISISKAGITTTLNART 535
Query: 480 SILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC 539
SILAAANP+ GRY+ S +N+ L ++SRFD+ F+++D + D +A+ + +H
Sbjct: 536 SILAAANPLYGRYNPKISPVENINLPAALLSRFDVLFLILDSPTREDDERLAQHVCFVHM 595
Query: 540 -NKEESYDCVYSRDDLLR-YIAFARSFKPVITEEAGKLLVEYY---XXXXXXXXXXXXXX 594
N D L+R YIA R +P + + + +V Y
Sbjct: 596 HNTHPELDFEPVEPTLMRHYIAECRKIEPRVPQALSEYIVSSYVQMRKQQQEDEAEEKSH 655
Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKS 636
++ R L +++RL++ +A++ V V EA RL++ S
Sbjct: 656 SYVSARTLLAVLRLSQALARLRHDDIVQQGDVDEALRLMDVS 697
Score = 46.4 bits (105), Expect = 0.003
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 4/95 (4%)
Query: 146 VHPELVQGTFYTIPTICRNPVCANRR---RFMLDADKSVFVDFQKIRIQETQAELPRGCI 202
+ E+ Q F + T+C + VC + + + S F FQ+++IQE ++P G I
Sbjct: 243 IFQEITQKHFAPL-TVCPSDVCVRNQTNGQLHMQTRASRFRPFQEVKIQEMADQVPVGHI 301
Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVG 237
PRS+ + L SV GD G I P G
Sbjct: 302 PRSMTIHLYGALTRSVNPGDVVHIGGIFIPTPYTG 336
>UniRef50_A0RYB8 Cluster: Cdc46/Mcm DNA replication licensing factor
ATPase; n=2; Thermoprotei|Rep: Cdc46/Mcm DNA replication
licensing factor ATPase - Cenarchaeum symbiosum
Length = 697
Score = 267 bits (654), Expect = 9e-70
Identities = 169/517 (32%), Positives = 271/517 (52%), Gaps = 24/517 (4%)
Query: 117 PTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLD 176
P + +RE+ I + +SG +VR V P L + Y+ P R V + +
Sbjct: 106 PVQRSLREINADIINKMTSVSGMVVRASEVKP-LAKELVYSCPEGHRTTVVLLKG---MG 161
Query: 177 ADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDV 236
K +E + + P +++ E E + G + + + D+
Sbjct: 162 VKPPTRCSDPKCSHRELEPK-PESSKFIDFQILRMQELPEDLPPGQLPHYI-EVAIKQDL 219
Query: 237 GALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAE 296
+ PG R ++ ++ + E + GL G+ Y+ +V+ + R A
Sbjct: 220 VDSARPGDRIILSGVVRI----EQEHVTGL---GMNSGLYRLRIDGNNVEFLGGRGAKA- 271
Query: 297 LPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFG 356
+ R++++ +E ++ +SR ++Y +LI S P I G +K +LL++ G
Sbjct: 272 ------SRRSEREEISPEEEKQIRLLSRGEDIYKDLINSFAPHIKGQELIKEAILLLIVG 325
Query: 357 GVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVV 416
+ G+ +RGDIN+ +VGDP TAKS++LK + I PR +YTSG+ S+AAGLTAAVV
Sbjct: 326 STQRHLGTGSKIRGDINIFLVGDPGTAKSEMLKFCALIAPRGLYTSGRGSTAAGLTAAVV 385
Query: 417 RDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLN 476
RD+ ++EAGA++L D G+ CIDEFDKM P D+ A+HE MEQQ+ S+AK G+ ATLN
Sbjct: 386 RDKSGI-MMLEAGAVVLGDQGLVCIDEFDKMKPEDRSALHEVMEQQSASIAKGGIVATLN 444
Query: 477 ARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVD 536
ARTSILAAANP+ G+YD K++ NV L P+++RFDL F++ D SE D IA+ I++
Sbjct: 445 ARTSILAAANPMYGKYDTYKNITDNVNLPVPLLTRFDLIFVVKDTPSEERDRNIAQHIIN 504
Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWR 596
LH + D L +Y++FA+ P+++ A K +++YY
Sbjct: 505 LHTPGGTDARSLIDPDTLTKYLSFAKRHDPLLSPGAEKKIIDYYLEMRHVDSPDMIT--- 561
Query: 597 ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
+T RQLE ++RL+ A++ V A +L+
Sbjct: 562 VTPRQLEGLIRLSTARARLLMKSRVEEEDAERAIQLM 598
>UniRef50_Q6R8Y2 Cluster: Minichromosome maintenance protein 5; n=2;
Entamoeba histolytica|Rep: Minichromosome maintenance
protein 5 - Entamoeba histolytica
Length = 639
Score = 266 bits (653), Expect = 1e-69
Identities = 152/323 (47%), Positives = 201/323 (62%), Gaps = 10/323 (3%)
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391
LI S+ P+I G +++K VL ++ GG K +GT LRGDINV ++GDP TAKSQLLK V
Sbjct: 312 LIKSIAPAICGYDDIKEAVLCLMLGGSGKALPDGTHLRGDINVLLMGDPGTAKSQLLKFV 371
Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451
TP VYTSGK SSAAGLTAAV +D + +F +E GAL+L D GV CIDEFDKM+ D
Sbjct: 372 QMATPIGVYTSGKGSSAAGLTAAVNKDSSTGEFYLEGGALVLGDGGVVCIDEFDKMNEVD 431
Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511
+VAIHEAMEQQTIS+AKAG+ A LNAR+++LAAANP GR++ S NV L I+SR
Sbjct: 432 RVAIHEAMEQQTISIAKAGITAVLNARSAVLAAANPSFGRFNERASFGDNVNLKTTILSR 491
Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSF-KPVITE 570
FD+ F++ D+ D I + I+D+H ++ D + S D L YIA+ +++ P +TE
Sbjct: 492 FDMIFMIRDKHDAKRDKEIVKHIMDIH-RQDVKVDNL-STDILKEYIAYCKAYCIPRLTE 549
Query: 571 EAGKLLVEYYXXXXXXXXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHCSGHVTPAH 625
A L Y+ ITVRQLE+++R++E +AKM S H
Sbjct: 550 NASNKLSNYFVSIRQKVRENKLENDNDEGIPITVRQLEAIIRISEALAKMTMSDIADENH 609
Query: 626 VHEAYRLLNKSIIR--VEQPDIH 646
V EA RL S + V Q + H
Sbjct: 610 VDEAIRLFELSTMNSAVRQKEKH 632
>UniRef50_A2FUI9 Cluster: MCM2/3/5 family protein; n=1; Trichomonas
vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas
vaginalis G3
Length = 698
Score = 265 bits (649), Expect = 4e-69
Identities = 146/332 (43%), Positives = 189/332 (56%), Gaps = 3/332 (0%)
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391
+I + P I+G +VK + LF GV K +G +RGDINV ++GDPS AKSQLLK
Sbjct: 303 IIKAFAPEIYGMQDVKEAICCQLFSGVRKNLPDGMKIRGDINVLLLGDPSVAKSQLLKFA 362
Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451
+TP VYTSGK SSAAGLTA VVR + S +F +E GA++LAD G+ CIDEFDKM D
Sbjct: 363 HSVTPIGVYTSGKGSSAAGLTATVVRAKGSGEFFLEGGAMVLADGGLVCIDEFDKMREDD 422
Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511
+VAIHEAMEQQTIS+AKAG+ A LN RT++LAAANP+ GR+D K+ + NV I+SR
Sbjct: 423 RVAIHEAMEQQTISIAKAGITAVLNTRTAVLAAANPVSGRFDDLKTARDNVDFQTTILSR 482
Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSF-KPVITE 570
FDL F+L D E D IA ++ +H DL ++I R+ P + +
Sbjct: 483 FDLIFVLRDVKDEARDRNIAEHVLKIHTGAGAEQTNNTQTGDLKKFIQHVRAHCNPSLGD 542
Query: 571 EAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAY 630
A LL Y ITVRQLE+++R+ E +AKM HV EA
Sbjct: 543 AANNLLKSEYVQMRSQIDNTQSI--PITVRQLEALIRVTESLAKMEQKDECKEEHVREAI 600
Query: 631 RLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQ 662
RL S I E E +V++
Sbjct: 601 RLFKVSTFNAASTGILAPEGPMTDEQRQEVNK 632
>UniRef50_Q01BJ5 Cluster: Minichromosome maintenance family protein
/ MCM family protein; n=2; Ostreococcus|Rep:
Minichromosome maintenance family protein / MCM family
protein - Ostreococcus tauri
Length = 787
Score = 264 bits (647), Expect = 6e-69
Identities = 148/324 (45%), Positives = 199/324 (61%), Gaps = 12/324 (3%)
Query: 326 RNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKS 385
+ + +L + P+I G++++K V +LF G K +GTT RGD+NV ++GDPSTAKS
Sbjct: 382 KEMLKDLRARIAPAIFGSDDIKAAVACLLFSGTRKHHPDGTTRRGDVNVLLLGDPSTAKS 441
Query: 386 QLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFD 445
Q LK V P VYTSGK SSAAGLTA+V+R ++ +F +E GA++LAD G CIDEFD
Sbjct: 442 QFLKFVERTAPVCVYTSGKGSSAAGLTASVIRGADN-EFYLEGGAMVLADGGCVCIDEFD 500
Query: 446 KMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALS 505
KM D+VAIHEAMEQQTIS+AKAG+ LN+RT++LAAANP GRYD K+ Q+N+ L
Sbjct: 501 KMRDEDRVAIHEAMEQQTISIAKAGITTMLNSRTAVLAAANPPSGRYDDLKTAQENIDLQ 560
Query: 506 PPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCV------YSRDDLLRYIA 559
I+SRFD+ FI+ D D IA ++++H + V R L RYI
Sbjct: 561 TTILSRFDMIFIVRDAREYERDMQIADHVLNIHAGGGDELALVSDPVQEKERQFLKRYIE 620
Query: 560 FARSF-KPVITEEAGKLL----VEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAK 614
+AR+ +P ++E A K+L V Y ITVRQLE+++R++E +AK
Sbjct: 621 YARAVCRPRLSERAMKMLEDSYVRYREEMRERKRTGGHAAVPITVRQLEAIIRISESLAK 680
Query: 615 MHCSGHVTPAHVHEAYRLLNKSII 638
M VT HV EA RL S I
Sbjct: 681 MCLQTVVTEEHVQEALRLFEVSTI 704
Score = 37.9 bits (84), Expect = 1.1
Identities = 19/56 (33%), Positives = 30/56 (53%)
Query: 173 FMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
F + +KSVF+D Q I++QE + G +PR++ ++ V SV G R G
Sbjct: 266 FRIVPEKSVFIDQQNIKLQENPECVQAGEMPRNMSALIERTMVLSVVPGTRVKIMG 321
>UniRef50_Q8SSE5 Cluster: DNA REPLICATION LICENSING FACTOR OF THE
MCM FAMILY; n=1; Encephalitozoon cuniculi|Rep: DNA
REPLICATION LICENSING FACTOR OF THE MCM FAMILY -
Encephalitozoon cuniculi
Length = 708
Score = 264 bits (647), Expect = 6e-69
Identities = 140/332 (42%), Positives = 204/332 (61%), Gaps = 7/332 (2%)
Query: 308 RKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTT 367
RK + DK+ E+ + ++Y L S+ PS+ G + K+ ++L LFGGV K + +
Sbjct: 297 RKIESSDPIDKIDELRKRPDVYEILANSVAPSVCGMEDTKKALVLQLFGGVRKE-LGSSR 355
Query: 368 LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIE 427
LRGDIN+ + GDP +KSQLL + + R +YTSG+ SSA GLTA+V +D ++ F++E
Sbjct: 356 LRGDINILLAGDPGISKSQLLSFIHRTSERGMYTSGRGSSAVGLTASVAKDPDTGQFILE 415
Query: 428 AGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP 487
+GAL+L+DNG+CCIDEFDKM + +HE MEQQT+S+AKAG+ TLNAR SILA+ NP
Sbjct: 416 SGALVLSDNGICCIDEFDKMSDSTRSVLHEVMEQQTVSVAKAGIITTLNARCSILASCNP 475
Query: 488 IGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDC 547
I +Y+ KS+ +N+ L P ++SRFD+ ++ID E D I IV L+ EE+
Sbjct: 476 IESKYNPRKSIVENINLPPTLLSRFDVVCLMIDRCDEFYDRTIGDHIVSLY--SEETQRK 533
Query: 548 VYSRDDLLR-YIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMV 606
Y DLL+ Y+ AR P +T E+ K+L + Y T RQLES++
Sbjct: 534 EYIDADLLKAYVREARRIVPRLTPESMKMLTQSYVDLRQMDNGKTITA---TTRQLESLI 590
Query: 607 RLAEGVAKMHCSGHVTPAHVHEAYRLLNKSII 638
RL+E A+M S V V EA R++ +S++
Sbjct: 591 RLSEAHARMRFSNAVEAKDVREAVRIIRESLL 622
Score = 53.6 bits (123), Expect = 2e-05
Identities = 36/127 (28%), Positives = 58/127 (45%), Gaps = 14/127 (11%)
Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYT-------IPTICRNPV-------C 167
+R + I +++ISG ++R+ V PE+V+ F + RN + C
Sbjct: 143 IRNIDPNDIDKIVQISGMVIRSSSVIPEIVRAFFRCSRCGHECLVESVRNVIDEPNKCEC 202
Query: 168 ANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFT 227
+ L + S F D Q +RIQE +P G P ++ ++ R E V+ + GDR T
Sbjct: 203 GGKYTQQLVHNASEFEDKQVVRIQELPEGIPNGTTPMAMTIVCRNEFVDGLVPGDRVKLT 262
Query: 228 GTLIVVP 234
G L P
Sbjct: 263 GVLKATP 269
>UniRef50_A7F6V0 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Sclerotinia sclerotiorum 1980
Length = 966
Score = 264 bits (647), Expect = 6e-69
Identities = 174/531 (32%), Positives = 280/531 (52%), Gaps = 25/531 (4%)
Query: 11 SQVKDEVGIRCQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLA 70
+Q++DE + Q+FL+ + + Y +L+ + L VS D+V +N LA
Sbjct: 4 AQLRDEAVADRVRSAQEFLDP-TDGSARTYRSDIILMLQKKQRRLIVSIDEVRAHNPELA 62
Query: 71 TTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKV--RELTTA 128
++E+ + +RA+ + ++ T ++ +D Y +F + R L++
Sbjct: 63 NGLLEQPFDFAQAFDRALFQIVQTIPNTNARQSSEDTMYYCAFSGSFGQFACNPRTLSST 122
Query: 129 KIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQKI 188
+ ++ + G + R V P++V+ Y + + + M + S + +
Sbjct: 123 HLNRMVSLEGIVTRCSLVRPKVVKSVHYNEKKKIFH-FREYKDQTMTASGASTSSVYPQE 181
Query: 189 RIQETQAELPRG-CIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAE 247
Q G C R + I E E AG + +I+ D+ PG R +
Sbjct: 182 DEQGNPLITEYGYCTYRDHQTISIQEMPERAPAG-QLPRGVDVILDDDLVDKVKPGDRVQ 240
Query: 248 ITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDM 307
+ G + G + G +KT LA +V +S + G + TH +T D+
Sbjct: 241 LV--------GIYRSL-GNRNAGHSSALFKTVVLANNVVLLSSKSGGG-IATHTITDTDI 290
Query: 308 RKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTT 367
R + ++++ +NL+N L SL PSI+G+ +K+ +LLML GG+ K GT
Sbjct: 291 RN---------INKIAKKKNLFNLLSQSLAPSIYGHEHIKKAILLMLLGGLEKNLENGTH 341
Query: 368 LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIE 427
LRGDIN+ +VGDPSTAKSQ+L+ V P A+ T+G+ SS GLTAAV D+E+ + +E
Sbjct: 342 LRGDINILMVGDPSTAKSQVLRFVLNTAPLAIATTGRGSSGVGLTAAVTSDKETGERRLE 401
Query: 428 AGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP 487
AGA++LAD GV CIDEFDKM D+VAIHE MEQQT+++AKAG+ +LNAR S++AAANP
Sbjct: 402 AGAMVLADRGVVCIDEFDKMSDIDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVIAAANP 461
Query: 488 IGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
I G+YD K +N+AL ++SRFDL F++ D+ + D I+ ++ +H
Sbjct: 462 IFGQYDTHKDPHKNIALPDSLLSRFDLLFVVTDDIEDFRDRQISEHVLRMH 512
Score = 38.7 bits (86), Expect = 0.61
Identities = 32/126 (25%), Positives = 57/126 (45%), Gaps = 7/126 (5%)
Query: 556 RYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWR-ITVRQLESMVRLAEGVA 613
+YI +A++ KP++T+EA + + Y +TVR LE+++RL+ A
Sbjct: 583 KYIQYAKTRIKPLLTQEASDRISDIYVALRNDDMQGNQRKTNAMTVRTLETIIRLSTAHA 642
Query: 614 KMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTAETPS 673
K S V E L +SI+R L++++ +DE +G + S
Sbjct: 643 KSRLS-----TRVEEVDALAAESILRFALFKEVLEDEKKSKRRKTRPLEDESSGNESSSS 697
Query: 674 NGDSAP 679
+ D +P
Sbjct: 698 DDDDSP 703
>UniRef50_Q9GR06 Cluster: DNA replication licensing factor MCM4;
n=12; Plasmodium|Rep: DNA replication licensing factor
MCM4 - Plasmodium falciparum
Length = 1005
Score = 262 bits (643), Expect = 2e-68
Identities = 150/423 (35%), Positives = 233/423 (55%), Gaps = 16/423 (3%)
Query: 146 VHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRS 205
V+ ++QG P C N C N+ F L + F Q I++ E L +G P+S
Sbjct: 347 VYEHVIQGEVQE-PVTCSN--CNNKNTFELWHNNCCFSSKQLIKLSEVTEHLKQGETPQS 403
Query: 206 LEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKG 265
+ + + ++ + GD + TG L P P SR + N +
Sbjct: 404 ISIYAYDDLIDYTKPGDTVELTGILKASP---VRLNPRSRCYNSVHRTYIN------VIH 454
Query: 266 LKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRD 325
+K +++ ++ GT E + E T + K+ ++S+D
Sbjct: 455 IKKENKQKMKLTEQNDTANIILKRNEDGTVE-ENFEKLNEQGNLLFTTEVIQKMEQLSKD 513
Query: 326 RNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKS 385
N+Y L+ S+ PSI+G ++K+G+L LFGG T R +I++ + GDPSTAKS
Sbjct: 514 PNIYQRLVDSIAPSIYGRGDIKKGLLCQLFGGSKITDKYNNKYRSEIHILLRGDPSTAKS 573
Query: 386 QLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFD 445
QLL V +++PR +YTSGK SS+ GLTA + +D E+ ++++E+GA++L+D G+CCIDEFD
Sbjct: 574 QLLHYVHKLSPRGIYTSGKGSSSVGLTAFISKDSETKEYILESGAVVLSDKGICCIDEFD 633
Query: 446 KMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALS 505
KMD + +HE MEQQT+++AKAG+ ATLNARTSILA+ANPI RYD+ K++ +N+ L
Sbjct: 634 KMDDSARAILHEVMEQQTVTIAKAGIVATLNARTSILASANPINSRYDKNKAVVENINLP 693
Query: 506 PPIMSRFDLFFILIDESSEMVDYAIAR---KIVDLHCNKEESYDCVYSRDDLLRYIAFAR 562
P + SRFDL +++ID+++E D +A K + +EE D +D YI R
Sbjct: 694 PSLFSRFDLIYLVIDQANEDEDRKLATVLCKNFSYNPEEEEDEDQEDQEEDEPNYITQQR 753
Query: 563 SFK 565
+ K
Sbjct: 754 ARK 756
Score = 50.4 bits (115), Expect = 2e-04
Identities = 31/96 (32%), Positives = 51/96 (53%), Gaps = 4/96 (4%)
Query: 540 NKEESYDCVYSRDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRIT 598
NK+ S + + + L YIA+ R + P+I+ E+ K+++E Y +
Sbjct: 813 NKKTSKNYLIDSNTLALYIAYCRITCNPIISLESKKIIIEEYIKMRCKEGTKSPTA---S 869
Query: 599 VRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN 634
RQLE +VRL++ +AKM V+P +EA RL+N
Sbjct: 870 PRQLEGLVRLSQSLAKMKLKRVVSPEEANEAVRLMN 905
>UniRef50_Q21902 Cluster: DNA replication licensing factor mcm-5;
n=3; Bilateria|Rep: DNA replication licensing factor
mcm-5 - Caenorhabditis elegans
Length = 759
Score = 262 bits (643), Expect = 2e-68
Identities = 208/660 (31%), Positives = 326/660 (49%), Gaps = 71/660 (10%)
Query: 25 FQDFLEEFKEDN-EIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83
F++F+ +F + Y K LE++ + ++ +++++ + + ++ P
Sbjct: 39 FRNFIRDFSTGGFGMIYRDQLKRNYFSHEYRLEINLNHLKNFDEDIEMKLRKFPGKVLPA 98
Query: 84 LNRA---ILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQI 140
L A + + I + G +K L D + ++ + PT +R++ +A++ +++ISG I
Sbjct: 99 LEEAAKIVADEITTPRPKGEEK-LHDIQVTLTLDEYPT--SLRQVKSAQVSQVVKISGII 155
Query: 141 VRTHPVHPELVQGTF------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQ-ET 193
V V + + T +TIP + P F L + Q R +
Sbjct: 156 VAAAQVRSKATKVTLQCRQCKHTIPDVSIKP---GLEGFALPRTCAAPQQGQMQRCPIDP 212
Query: 194 QAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTK 253
LP C + + E E V G+ L + +PG+R I
Sbjct: 213 YIMLPDKCECVDYQTLKLQENPEDVPHGEMPRHL-QLFTERYLTDKVVPGNRVTIVGVYS 271
Query: 254 LANEGQMEGIKGLKAL-GVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMT 312
+ Q +G G K+L G+R + + + R T T E+ R T
Sbjct: 272 IKKLIQKKG--GDKSLQGIRTPYLRVLGIHMETSGPGRTNFTT------FTPEEERMFKT 323
Query: 313 DKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDI 372
+++ ++ Y + S+ PSI+G+ ++K+ + +LFGG K +G T RGDI
Sbjct: 324 ---------LAQRKDAYELIAKSIAPSIYGSADIKKSIACLLFGGARKKLPDGITRRGDI 374
Query: 373 NVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALM 432
NV ++GDP TAKSQLLK V +++P VYTSGK SSAAGLTA+V+RD +S F++E GA++
Sbjct: 375 NVLLLGDPGTAKSQLLKFVEQVSPIGVYTSGKGSSAAGLTASVIRDPQSRSFIMEGGAMV 434
Query: 433 LADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRY 492
LAD GV CIDEFDKM D+VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+
Sbjct: 435 LADGGVVCIDEFDKMREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVYGRW 494
Query: 493 DRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCN----KEESY--- 545
D ++ N+ P I+SRFD+ +I+ D + D +A+ ++++H N KE
Sbjct: 495 DESRG-DDNIDFMPTILSRFDMIYIVKDTHDVLKDATLAKHVIEVHVNASAAKERDIAGV 553
Query: 546 --------DCVYSRDD---------LLRYIAFAR-SFKPVITEEAGKLLVEYY------- 580
D V + D L +++ +AR + P +T +A + LV +Y
Sbjct: 554 PKTATTDSDGVMTMFDTDGFLTIEFLKKFVTYARLNCGPRLTPQASEKLVNHYVKMRNPV 613
Query: 581 --XXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSII 638
ITVRQLE++VR+AE +AKM T HV EA RL S I
Sbjct: 614 VNADAFKSGKKAHNSAIPITVRQLEAIVRIAESIAKMELQQFATDKHVEEALRLFRVSTI 673
>UniRef50_P29469 Cluster: DNA replication licensing factor MCM2;
n=17; Ascomycota|Rep: DNA replication licensing factor
MCM2 - Saccharomyces cerevisiae (Baker's yeast)
Length = 868
Score = 262 bits (641), Expect = 3e-68
Identities = 165/457 (36%), Positives = 250/457 (54%), Gaps = 55/457 (12%)
Query: 108 ECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPEL------------VQGTF 155
E +V D PT + +REL + + +L+R++G + R V P+L + G F
Sbjct: 292 EIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPF 351
Query: 156 YTIP------TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVI 209
+ + C N C ++ F ++ +K+V+ ++Q++ +QE +P G +PR EVI
Sbjct: 352 FQDSNEEIRISFCTN--CKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVI 409
Query: 210 LRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKAL 269
L A+ V+ +S PG E+T K +G + G
Sbjct: 410 LLADLVD----------------------VSKPGEEVEVTGIYKNNYDGNLNAKNGFPV- 446
Query: 270 GVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLY 329
+ T A S++ R TA L T++E + ++SRDR +
Sbjct: 447 ------FATIIEANSIK--RREGNTANEGEEGLDV----FSWTEEEEREFRKISRDRGII 494
Query: 330 NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLK 389
+ +I+S+ PSI+G+ ++K V LFGGV K ++RGDINV ++GDP TAKSQ+LK
Sbjct: 495 DKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILK 554
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
V + RAV+ +G+ +SA GLTA+V +D + ++ +E GAL+LAD GVC IDEFDKM+
Sbjct: 555 YVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMND 614
Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509
D+ +IHEAMEQQ+IS++KAG+ TL AR SI+AAANP GGRY+ L QNV+L+ PI+
Sbjct: 615 QDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPIL 674
Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYD 546
SRFD+ ++ D E D +A +VD H D
Sbjct: 675 SRFDILCVVRDLVDEEADERLATFVVDSHVRSHPEND 711
>UniRef50_Q54LI2 Cluster: MCM family protein; n=2; Eukaryota|Rep:
MCM family protein - Dictyostelium discoideum AX4
Length = 1008
Score = 261 bits (639), Expect = 6e-68
Identities = 148/371 (39%), Positives = 217/371 (58%), Gaps = 19/371 (5%)
Query: 292 FGTAELPTHDLTTEDMRKQ--MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349
F T H ED+ +TD++ ++ ++S+D N+ +I S+ PSI+G+ ++K G
Sbjct: 545 FSTIIEANHINKKEDLLSSFILTDEDEREIRKLSKDSNIAQKIIQSIAPSIYGHEDIKTG 604
Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409
+ L LFGG K +RGDINV ++GDP AKSQ LK V + RAVYT+G+ +SA
Sbjct: 605 LALALFGGTPKDVNNKHRIRGDINVLLIGDPGVAKSQFLKYVEKTAHRAVYTTGQGASAV 664
Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469
GLTAAV D + ++ +E GAL+LAD GVC IDEFDKM+ D+ +IHEAMEQQ+IS++KA
Sbjct: 665 GLTAAVRMDPLTREWTLEGGALVLADRGVCMIDEFDKMNDQDRTSIHEAMEQQSISISKA 724
Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529
G+ TL AR S++AAANP G+YD +L QNV L+ PI+SRFD+ ++ D D
Sbjct: 725 GIVTTLTARCSVIAAANPKRGKYDSGLNLLQNVELTEPILSRFDIICVVKDTIDSFKDRE 784
Query: 530 IARKIVDLHCNK--------EESY------DCVYSRDDLLRYIAFARSFKPVITEEAGKL 575
+AR +V H N E Y S++ L +YI +A+ KP IT+
Sbjct: 785 LARFVVASHINSHPDNQNNPENDYLNRATKQSPISQELLRKYIIYAKRIKPRITDIDKNK 844
Query: 576 LVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNK 635
+ + Y + +TVR +ES+VR+AE AKMH +VT V+ + R++
Sbjct: 845 ISQLYTDLRRESRAGG---FAMTVRHVESIVRMAEAHAKMHLRDYVTDFDVNTSIRVMLD 901
Query: 636 SIIRVEQPDIH 646
S I ++ ++
Sbjct: 902 SFINAQKNSMY 912
Score = 63.7 bits (148), Expect = 2e-08
Identities = 50/227 (22%), Positives = 107/227 (47%), Gaps = 25/227 (11%)
Query: 23 KLFQDFLEEFKEDNEIK--YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRI 80
K F FL EFKE + Y++ +++ +L ++F + + + E +
Sbjct: 304 KQFAKFLLEFKEKDGFNPIYQESIQKMCAANKESLMINFTHLCA-STVFGVWVAEIPTEM 362
Query: 81 YPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQI 140
+ L +L + +++ K +V +P +R++ + + L ++ G I
Sbjct: 363 IEIFDEVALKVVLRIYPN--YRNIV-KSIHVRITHLPICESLRDIRQSNLNKLTKVGGVI 419
Query: 141 VRTHPVHPEL------------------VQGTFY-TIPTICRNPVCANRRRFMLDADKSV 181
R V+P+L + GTF + P I P C ++ F+++++++V
Sbjct: 420 TRRSNVYPQLKHVKYDCVKCKTTLGPFSLDGTFNDSKPPIGLCPQCQSKGPFVMNSEQTV 479
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
+ DFQK+ +QE+ +P G +PR+ ++IL + +++V+ G+ + TG
Sbjct: 480 YRDFQKVTLQESPGTVPPGRLPRTKDIILMDDLIDTVRPGEEVEITG 526
>UniRef50_Q7ZAA5 Cluster: Mcm protein; n=5; Euryarchaeota|Rep: Mcm
protein - Archaeoglobus fulgidus
Length = 698
Score = 260 bits (638), Expect = 8e-68
Identities = 186/555 (33%), Positives = 282/555 (50%), Gaps = 61/555 (10%)
Query: 109 CYVSFVDVPTRHKV--RELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPV 166
C F +PT KV R L IG + I G + + V P +V+ F C N
Sbjct: 86 CKPRFYSLPTARKVLIRNLRAEHIGKFMAIEGIVRKVTEVRPRIVEAAF-----ACLN-- 138
Query: 167 CANRRRFMLDADKSVFVDFQKIRIQ-ETQAELPRGCIPRSLEVILRAEAVESVQAGDRYD 225
C + + D + F+ + + LP I + + E E+++ G++
Sbjct: 139 CGSIT-MVPQEDSQLRQPFECSKCSTKKMIFLPDSSISVDSQRVKIQEYPENLRGGEQPQ 197
Query: 226 FTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFL-ACS 284
T +I+ D+ PG R I + G LG R++ + ++ S
Sbjct: 198 -TIDVILEGDLAGSVNPGDRVIINGIVRAKPRG----------LGQRKMTHMDLYIEGNS 246
Query: 285 VQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNN 344
V+ + + + E+ T+K+ + + +++ ++Y ++ S+ PSI+G+
Sbjct: 247 VEVLQQEYEEFEI--------------TEKDRELIMQLAASDDIYEKIVKSIAPSIYGHE 292
Query: 345 EVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGK 404
+VK + L LFGGV K +GT +RGDI++ +VGDP AKSQLLK V I PR+VYT+GK
Sbjct: 293 DVKLAIALQLFGGVPKKLPDGTEIRGDIHILLVGDPGVAKSQLLKYVHRIAPRSVYTTGK 352
Query: 405 ASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTI 464
++ AGLTA VRDE + +EAGAL+LAD G+ +DE DKM D A+HEA+EQQTI
Sbjct: 353 GTTTAGLTATAVRDEVDGRWTLEAGALVLADKGIALVDEIDKMRKEDTSALHEALEQQTI 412
Query: 465 SLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSE 524
S+AKAG+ A L AR ++L AANP GR+++ + + + +SP ++SRFDL F+L DE E
Sbjct: 413 SVAKAGINAILKARCALLGAANPKYGRFEKFTPVPEQIEMSPTLLSRFDLIFVLKDEPDE 472
Query: 525 MVDYAIARKIVDLH---------CNKEESYDCVYSRD-----------DLLR-YIAFAR- 562
D + I+ H N YD + R DLLR YIA+AR
Sbjct: 473 EKDKRLVEHILYSHQLGEMTEKAKNVAAEYDEEFIRQRSERIVPEIDPDLLRKYIAYARK 532
Query: 563 SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVT 622
+ PV+T+EA + + E+Y IT RQLES+VRLAE A++ S V
Sbjct: 533 TVYPVLTDEAKEKIKEFYLSLRSRVKENSPV--PITARQLESIVRLAEASARVRLSDRVE 590
Query: 623 PAHVHEAYRLLNKSI 637
P V ++ +S+
Sbjct: 591 PEDVDRVIEIMMRSL 605
>UniRef50_Q5KDY4 Cluster: DNA replication licensing factor cdc19
(Cell division control protein 19), putative; n=9;
Dikarya|Rep: DNA replication licensing factor cdc19
(Cell division control protein 19), putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 932
Score = 260 bits (637), Expect = 1e-67
Identities = 203/650 (31%), Positives = 318/650 (48%), Gaps = 52/650 (8%)
Query: 14 KDEVGIRCQKLFQDFLEEFKE-DNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATT 72
+D V K F+ FL + + Y + K L + +LEVS+ + LA
Sbjct: 217 RDAVRRAISKHFKSFLMTYVDAQGNSVYGQRIKHLGEVNSESLEVSYIHLANTRPILAYF 276
Query: 73 IIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGT 132
+ + ++ L+ IL + D E +V ++PT +R+L + +
Sbjct: 277 LANSPQPMLELFDQVALDAILLYYPS---YDRIHSEIHVRITELPTSLSLRDLRQSNLNC 333
Query: 133 LIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVC-ANRRRFMLDADKSVFVDF-QKIRI 190
L+R+SG + R V P+L F C+ C A F D +K + + F Q
Sbjct: 334 LVRVSGVVTRRSGVFPQLKYVKFD-----CQK--CGATLGPFYQDTNKELKISFCQGCES 386
Query: 191 QETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITT 250
+ + R+ + + E+ SV AG R +I++ D+ ++ PG EIT
Sbjct: 387 RGPFVVNSEQTVYRNYQKMTLQESPGSVPAG-RLPRHREVILLWDLIDMAKPGEEVEIT- 444
Query: 251 RTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQ 310
GI + L+ K F S + E DL MR
Sbjct: 445 -----------GI--YRNNFDASLNTKNGFPVFSTVLEANHINKKE----DLFAA-MR-- 484
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRG 370
+T+++ + M+RD + ++ S+ PSI+G++++K + L LFGGV K +RG
Sbjct: 485 LTEEDEKMIRTMARDDRIAKRIVKSIAPSIYGHDDIKTAIALSLFGGVGKDINRKHRIRG 544
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGA 430
DINV ++GDP TAKSQ LK V + RAV+T+G+ +SA GLTA+V +D + ++ +E GA
Sbjct: 545 DINVLLLGDPGTAKSQFLKYVEKTANRAVFTTGQGASAVGLTASVRKDPITKEWTLEGGA 604
Query: 431 LMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGG 490
L+LAD G C IDEFDKM+ D+ +IHEAMEQQ+IS++KAG+ TL AR +I+AAANPI G
Sbjct: 605 LVLADKGHCLIDEFDKMNDADRTSIHEAMEQQSISISKAGIITTLQARCAIIAAANPIRG 664
Query: 491 RYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYD---- 546
RY+ QQNV L+ PI+SRFD+ ++ D + + D +A+ +V H +D
Sbjct: 665 RYNPTIPFQQNVELTEPILSRFDVLCVVKDAADPVQDEMLAQFVVGSHLRSHPLFDKEHE 724
Query: 547 ----------CVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXW 595
+ +D L +YI +A+ F+P + + L Y +
Sbjct: 725 EANVSTVIDADIIPQDVLRKYIMYAKEHFRPQLHQLDQDKLARLY--ADLRRESLATGSF 782
Query: 596 RITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDI 645
ITVR LESM+R+AE AKMH +V + A ++ S + ++ I
Sbjct: 783 PITVRHLESMIRMAEASAKMHLREYVRTDDIDLAIQVAVGSFVSAQKMSI 832
>UniRef50_Q8WSL5 Cluster: DNA replication licensing factor MCM5;
n=9; Plasmodium|Rep: DNA replication licensing factor
MCM5 - Plasmodium falciparum
Length = 758
Score = 258 bits (633), Expect = 3e-67
Identities = 141/327 (43%), Positives = 197/327 (60%), Gaps = 5/327 (1%)
Query: 314 KEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDIN 373
+E +++ ++ + N++ + S+ P ++G +EVK+ +LFGG K E T +RGDIN
Sbjct: 351 EERNELTLLAAEHNIHEKIFKSIAPELYGMDEVKKACACLLFGGTRKRIGEETKIRGDIN 410
Query: 374 VCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALML 433
+ ++GDPS AKSQ+LK V+ P +VYTSGK SSAAGLTAAV+RD + F +E GA++L
Sbjct: 411 MLMLGDPSVAKSQILKFVNRCAPVSVYTSGKGSSAAGLTAAVMRDSQGV-FSLEGGAMVL 469
Query: 434 ADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYD 493
AD GV CIDEFDKM D VAIHEAMEQQTIS++KAG+ LN R S++AAANP G YD
Sbjct: 470 ADGGVVCIDEFDKMRDDDVVAIHEAMEQQTISISKAGITTMLNTRCSVIAAANPSFGSYD 529
Query: 494 RAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDD 553
++ I+SRFD+ F+L ++ D + IV LH +K +S +
Sbjct: 530 DSQDTTYQHDFKTTILSRFDIIFLLRNKQDVEKDTLLCNHIVALHASKHKSQEGEIPLSK 589
Query: 554 LLRYIAFA-RSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWR---ITVRQLESMVRLA 609
L RYI +A R P++++EA L +Y + IT+RQLES++RLA
Sbjct: 590 LTRYIQYAKREIAPLLSKEARDSLRNFYVQTRAEYRGDRRSVTKKIPITLRQLESLIRLA 649
Query: 610 EGVAKMHCSGHVTPAHVHEAYRLLNKS 636
E AKM S T HV + L + S
Sbjct: 650 ESFAKMELSQFATDKHVQMSIDLFSAS 676
Score = 35.1 bits (77), Expect = 7.5
Identities = 17/58 (29%), Positives = 31/58 (53%)
Query: 173 FMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTL 230
+++ ++ FVD Q +++QE +P G +PR L++ + E + GDR G L
Sbjct: 253 YVILPNECTFVDIQSLKMQELPEAVPTGDMPRHLQLNVTRYLCEKMIPGDRVYVHGVL 310
>UniRef50_A2F017 Cluster: MCM2/3/5 family protein; n=1; Trichomonas
vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas
vaginalis G3
Length = 799
Score = 252 bits (618), Expect = 2e-65
Identities = 172/494 (34%), Positives = 263/494 (53%), Gaps = 62/494 (12%)
Query: 168 ANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFT 227
AN ++ S F+D Q I IQE P G +PR+ +VI A
Sbjct: 188 ANDNPLEVEYGFSTFIDHQIITIQERPESAPAGQMPRNCDVIADA--------------- 232
Query: 228 GTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQA 287
D+ PG R ++ ++ +++G A G+ Y +A S++
Sbjct: 233 -------DLADACKPGDRVKVYGVYRIL-PNKVQGT----ASGI----YHPLLIANSIEV 276
Query: 288 VSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVK 347
++ T +L E++R KE +++ ++ + ++ + L S+ PSI+G++ +K
Sbjct: 277 AAQ---TLQLNLTKSDVENIRFIAGYKENNQL-DVEENTHVLDLLSRSIAPSIYGSSRIK 332
Query: 348 RGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASS 407
++LML GG +GT +RGDIN+ +VGDPSTAKSQLL+ V I P AV+T+G+ +S
Sbjct: 333 EAIVLMLAGGCETNLPDGTHIRGDINMLMVGDPSTAKSQLLRHVLNIAPLAVHTTGRGAS 392
Query: 408 AAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLA 467
GLTA+V D E+ + +EAGA+++AD GV CIDEFDKMD D+VAIHEA+EQQT++++
Sbjct: 393 GVGLTASVTTDTETGERRLEAGAMVIADRGVVCIDEFDKMDEADRVAIHEALEQQTVTIS 452
Query: 468 KAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVD 527
KAG+ ATLNAR S+ AAANP+ G Y+ +S NV L ++SRFDL FI++D+ + VD
Sbjct: 453 KAGIHATLNARCSVAAAANPVWGTYNPNRSPMDNVGLPDSLISRFDLLFIVLDQHNPQVD 512
Query: 528 YAIARKIVDLHCNKEE------SYDCVYSRDD------------------LLRYIAFARS 563
AIA +++ H K S D +Y + D L +YI +
Sbjct: 513 AAIADHVLENHKWKSNGPSTTYSDDGIYLKSDAIPHVSQGEQQNYVTVEFLKKYITHCKD 572
Query: 564 FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTP 623
KP +T+EA +LLV + IT R E+++RL+ AK+ S +T
Sbjct: 573 IKPTLTKEANELLVSPWADMRAVMTRKTQ---PITPRTFETLIRLSTAAAKIRLSSTITE 629
Query: 624 AHVHEAYRLLNKSI 637
+ A LL S+
Sbjct: 630 QDANTAISLLKFSV 643
>UniRef50_P33993 Cluster: DNA replication licensing factor MCM7;
n=52; Eukaryota|Rep: DNA replication licensing factor
MCM7 - Homo sapiens (Human)
Length = 719
Score = 252 bits (616), Expect = 4e-65
Identities = 132/314 (42%), Positives = 189/314 (60%), Gaps = 4/314 (1%)
Query: 325 DRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAK 384
+ + Y L S+ P I+G+ +VK+ +LL+L GGV ++ G +RG+IN+C++GDP AK
Sbjct: 329 EEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSP-RGMKIRGNINICLMGDPGVAK 387
Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEF 444
SQLL + + PR+ YT+G+ SS GLTAAV+RD S + +E GAL+LAD GVCCIDEF
Sbjct: 388 SQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEF 447
Query: 445 DKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVAL 504
DKM D+ AIHE MEQQTIS+AKAG+ TLNAR SILAAANP GRY+ +SL+QN+ L
Sbjct: 448 DKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQL 507
Query: 505 SPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL--RYIAFAR 562
++SRFDL +++ D D +A+ I +H + + D L RYIA R
Sbjct: 508 PAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCR 567
Query: 563 SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVT 622
+P++ E + Y + + R L +++RL+ +A++ V
Sbjct: 568 EKQPMVPESLADYITAAYVEMRREAWASKDATY-TSARTLLAILRLSTALARLRMVDVVE 626
Query: 623 PAHVHEAYRLLNKS 636
V+EA RL+ S
Sbjct: 627 KEDVNEAIRLMEMS 640
Score = 52.8 bits (121), Expect = 3e-05
Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 20/136 (14%)
Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF------------YTIPT-----ICRN 164
+RE+ +G L+ + G + R V P++V T+ PT +C +
Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208
Query: 165 PVCANRR---RFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAG 221
C R R L S F+ FQ++++QE ++P G IPRS+ V++ E Q G
Sbjct: 209 QECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPG 268
Query: 222 DRYDFTGTLIVVPDVG 237
D TG + + G
Sbjct: 269 DHVSVTGIFLPILRTG 284
>UniRef50_A0B5T2 Cluster: MCM family protein; n=1; Methanosaeta
thermophila PT|Rep: MCM family protein - Methanosaeta
thermophila (strain DSM 6194 / PT)
(Methanothrixthermophila (strain DSM 6194 / PT))
Length = 689
Score = 250 bits (612), Expect = 1e-64
Identities = 141/352 (40%), Positives = 214/352 (60%), Gaps = 22/352 (6%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
+++ ++ ++ E+SRD N+Y ++ S+ PSI+G +VK + L L G +K +G +R
Sbjct: 254 EISPEDEKRILELSRDPNIYEKIVRSIAPSIYGYEDVKEALALQLVSGFSKRLPDGARIR 313
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD-FVIEA 428
GDI++ +VGDP AKSQLL+ +++++PR +YTSGK+S++AGLTA ++DE + IEA
Sbjct: 314 GDIHILLVGDPGVAKSQLLRYMAKLSPRGIYTSGKSSTSAGLTATAIKDELGDGRWTIEA 373
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPI 488
GAL+LAD G+ +DE DKM P D+ A+HEAMEQQTIS+AKAGV ATL +R ++LAAANP
Sbjct: 374 GALVLADKGIAAVDEMDKMSPDDRSALHEAMEQQTISVAKAGVMATLKSRCALLAAANPK 433
Query: 489 GGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIV------DLHCNK- 541
GR+DR + + + L+P +MSRFDL F+L DE + D IA I+ +L NK
Sbjct: 434 MGRFDRYEPIAPQINLTPALMSRFDLIFVLTDEPNVERDSHIATHILKSNYAGELTSNKH 493
Query: 542 -----EESYDCVYS------RDDLLR-YIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXX 588
EE + +LLR Y+A+AR + P++T A + EYY
Sbjct: 494 NSSINEEEIENATEVIKPEIEPELLRKYVAYARKNVFPMLTRVAMERFKEYYINLRSQGQ 553
Query: 589 XXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRV 640
+T RQLE+++RL E A++ S +T V +++ + +V
Sbjct: 554 DGNKPV-PVTARQLEALIRLGEASARLRLSNWITEEDVDRVIKIVESCLKKV 604
Score = 72.1 bits (169), Expect = 5e-11
Identities = 57/198 (28%), Positives = 90/198 (45%), Gaps = 24/198 (12%)
Query: 50 PELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKEC 109
P +L V F D+++Y+ A ++E + + A+ +L + D+
Sbjct: 29 PSTRSLIVDFADLDRYDTEFADDLLENPDVMLDAAHTALQEIVLPV-------DVDLSGA 81
Query: 110 YVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQ----------------- 152
+V V++P K R+L + IG LI I GQ+ V P++V+
Sbjct: 82 HVRIVNLPQHLKTRDLRSDHIGKLIAIEGQVRTATEVRPKIVRAAYECQRCGHVFYVDQS 141
Query: 153 GTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRA 212
GT + P C N C R F L +S FVD QK+R+QE+ +L G P++L+V L
Sbjct: 142 GTKFIEPYECPNEACDRRGPFRLLPKRSQFVDAQKVRVQESPEDLRGGEQPQTLDVELGD 201
Query: 213 EAVESVQAGDRYDFTGTL 230
+ V + GDR G L
Sbjct: 202 DLVGRIFPGDRVIINGIL 219
>UniRef50_Q7QZN0 Cluster: GLP_680_44640_47504; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_680_44640_47504 - Giardia lamblia
ATCC 50803
Length = 954
Score = 250 bits (611), Expect = 1e-64
Identities = 121/271 (44%), Positives = 181/271 (66%), Gaps = 1/271 (0%)
Query: 276 YKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITS 335
+K +FL + +++ + T M ++D+ + V M D N+ +NL+ S
Sbjct: 385 HKPSFLIAFEEQLTKHSDEVANEDVEQTLAAMLDSLSDEYREAVSNMRNDPNIVSNLVAS 444
Query: 336 LFPSIHGNNEVKRGVLLMLFGGVAKTT-IEGTTLRGDINVCIVGDPSTAKSQLLKQVSEI 394
P I+G+ VK G+LL L GG+ K T E ++R DIN+ ++GDPSTAKSQLL+ ++
Sbjct: 445 FAPHIYGHETVKLGILLQLLGGIKKITRSEHLSIRSDINILLIGDPSTAKSQLLQYTADF 504
Query: 395 TPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVA 454
+AVYTSGK+S+AAGLTAAVV D ++ ++ +EAGAL+ AD G+C IDEF+K+ DQ A
Sbjct: 505 HQKAVYTSGKSSTAAGLTAAVVTDPDTGEYTVEAGALIRADGGLCLIDEFEKISVTDQTA 564
Query: 455 IHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDL 514
+HE +EQQ++S+ KAG+ TL A+T +LAA NPIG RY R KSL+ N+ +S PI+SRFDL
Sbjct: 565 LHECLEQQSVSINKAGISITLKAKTPVLAAMNPIGSRYQRNKSLKNNINISQPILSRFDL 624
Query: 515 FFILIDESSEMVDYAIARKIVDLHCNKEESY 545
F+L+DE ++ VD +A +I+ + + +Y
Sbjct: 625 AFVLLDEPNKEVDNFVASRIITMQVLRNTAY 655
Score = 74.5 bits (175), Expect = 1e-11
Identities = 78/306 (25%), Positives = 137/306 (44%), Gaps = 62/306 (20%)
Query: 40 YEKHAKELLKPELSTLEVSFDDVEKY--NQNLATTIIEEYYRIYPFLNRAI---LNYILS 94
Y + ++++ + +TL ++F + Q T+ +++Y P + AI LN L+
Sbjct: 46 YLRRMRQMIDNDSNTLYINFSHLYDNIRTQAYCETVRKQFYVFEPLIVEAIRIVLNTTLA 105
Query: 95 --------LAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPV 146
+ +G ++ L + Y+S + + ELT++ IG L+ + G + RT V
Sbjct: 106 PYRGAAFQVLTSGQQQVL--RPLYISCYGMNNVLLLSELTSSHIGQLVELVGTVTRTSDV 163
Query: 147 HPELVQGTFY------TIPTICRN---------PVCANRRR-----FMLDADKSVFVDFQ 186
PEL+ GTF IP + ++ P C+ R F L D+ F D Q
Sbjct: 164 QPELILGTFRCASCGEVIPNVAQDYKFTEPASCPRCSARSSVGGTTFELLTDQCTFADTQ 223
Query: 187 KIRIQETQAEL--------PRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGA 238
++R+QE+ A+ P P S +VILR ++ GDR + TG LIV P++ A
Sbjct: 224 RVRLQESIADTTTSEEGGDPTRITPASYDVILRETFAGVLKPGDRVNLTGCLIVQPNISA 283
Query: 239 LSMPGSRAEITTRTKLA----NEGQM---------------EGIKGLKALGVRELHYKTA 279
+SMP + ++ +A G M EG+ G+ +G+RE+ Y+
Sbjct: 284 MSMPYEIRSSSLKSVIAGYSIESGNMTSAAVQDNIQRGRYEEGVTGITGVGLREITYRNV 343
Query: 280 FLACSV 285
+ +
Sbjct: 344 IIGSHI 349
Score = 50.0 bits (114), Expect = 2e-04
Identities = 24/84 (28%), Positives = 46/84 (54%)
Query: 557 YIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMH 616
Y++ R+ +P++ ++A + + +RITVRQLES+VRL+E A++
Sbjct: 712 YLSLGRTIRPILQKDAIDEISHQWVELRRRDVGSTSRSFRITVRQLESLVRLSEAFARLC 771
Query: 617 CSGHVTPAHVHEAYRLLNKSIIRV 640
+ +T HV +A L++ + + V
Sbjct: 772 LATAITKEHVKKAAELVSTTCVNV 795
>UniRef50_Q3SAC5 Cluster: DNA replication licensing factor MCM
related protein; n=1; uncultured euryarchaeote
Alv-FOS1|Rep: DNA replication licensing factor MCM
related protein - uncultured euryarchaeote Alv-FOS1
Length = 682
Score = 250 bits (611), Expect = 1e-64
Identities = 198/633 (31%), Positives = 314/633 (49%), Gaps = 50/633 (7%)
Query: 30 EEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAIL 89
EEF +E + P +L V F+D+ + + + ++E+ + AI
Sbjct: 13 EEFLSQSEYSIKLLEVNDKYPYEKSLYVDFEDLVVFQPDFSEYVMEQPEKCLELGEAAIQ 72
Query: 90 NYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPE 149
NY+ T L+ + +F + ++R+L T IG + I G I R V P+
Sbjct: 73 NYL----NTNHHIHLRIIKISDNF-----KMEIRKLRTTHIGKFVAIRGIIRRASEVRPK 123
Query: 150 LVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVI 209
L G F N R + DK K +I+ +P + +V+
Sbjct: 124 LKIGAFKCSDCGGINYEEQPGNRLVYP-DKCEICGKPKGKIKFHL--VPEDSVFEDFQVV 180
Query: 210 LRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKAL 269
+ ES++ G++ T ++ D+ +PG R + K Q I+ L +
Sbjct: 181 EVQDTPESLRGGEQPQRI-TAVLKDDIAGTLVPGDRVIVNGIIK----AQEVRIQNLLST 235
Query: 270 GVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLY 329
R FL + ++ R DL+TE++ T+++ +++ E++RD
Sbjct: 236 EFR------MFL--DINSIDRE-------EKDLSTEEI----TEEDIEEIKELARDPEAI 276
Query: 330 NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLK 389
L S+ P+I+G + +K ++L +FGGV KT +GT +RGDI+V +VGDP TAKSQLL
Sbjct: 277 EKLKNSIAPTIYGMDTIKEALVLQMFGGVPKTMPDGTKIRGDIHVLLVGDPGTAKSQLLS 336
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
+++++ PR +YTSGK SSAAGLTA VRDE + +EAGAL+LAD G+ IDE DKM
Sbjct: 337 KMAQLAPRGIYTSGKGSSAAGLTATAVRDETG-RWTLEAGALVLADLGLAAIDEMDKMST 395
Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509
D+ +I++AMEQQ I++ KAG+ ATL +R S+L AANP GR+D S+ + L P++
Sbjct: 396 TDRDSIYQAMEQQIITVTKAGIYATLMSRCSVLGAANPKYGRFDPQSSIPNQIDLPVPLL 455
Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE----SYDCVYSR------DDLLR-YI 558
SRFD+ F ++D + D A A I+ +H E+ D + + +LLR Y+
Sbjct: 456 SRFDVIFKILDTPNPNRDKATAEHILKVHLVGEKLSLGEEDIIVEQHLGEISPELLRKYV 515
Query: 559 AFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHC 617
+A+ P ++++A K + E Y IT RQLE+M+RLAE A+
Sbjct: 516 IYAKEHVIPKLSDDALKRISEEYLKMRGMYSDENQRV-AITPRQLEAMIRLAEASARARL 574
Query: 618 SGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDED 650
S VT A R++ + + D D D
Sbjct: 575 SDVVTTEDAKRAIRIVKEYMKDASSEDGQPDAD 607
>UniRef50_UPI00004994EB Cluster: DNA replication licensing factor;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA
replication licensing factor - Entamoeba histolytica
HM-1:IMSS
Length = 608
Score = 249 bits (610), Expect = 2e-64
Identities = 137/333 (41%), Positives = 202/333 (60%), Gaps = 4/333 (1%)
Query: 307 MRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGT 366
++K + E D + + + Y L S+ PSI ++VK+G+L LFGG AKT +
Sbjct: 246 IKKYSKETEVDIDFTTLINDDWYERLTRSVAPSITEMDDVKKGLLCQLFGGSAKTLQDNQ 305
Query: 367 TLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVI 426
LRGDIN+ ++GDP T+KSQLL + ++ PR +YTSG+ SSA GLTA V + EE V+
Sbjct: 306 KLRGDINILMLGDPGTSKSQLLTFMHKVAPRGMYTSGRGSSAVGLTAFVGKSEEG-GTVL 364
Query: 427 EAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAAN 486
E+GAL+++D G+CCIDEFDKM + +HEAMEQQTIS+AK+G+ +LNART+ILA+AN
Sbjct: 365 ESGALVMSDKGLCCIDEFDKMTEMTRSVLHEAMEQQTISVAKSGIVCSLNARTAILASAN 424
Query: 487 PIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYD 546
P RY+ S+ N+ + P ++SRFDL ++++D+ + D +AR I+ L+ E D
Sbjct: 425 PKESRYNPKLSVLDNIQMPPSLLSRFDLIYLILDQPNPERDRKLARHIISLYWGHEIKTD 484
Query: 547 CVYSRDDLLRYIAFARS-FKPVITEEAGKLLVE-YYXXXXXXXXXXXXXXWRITVRQLES 604
+ ++ +AR KPV+T+ A LV+ Y T RQLES
Sbjct: 485 AL-DISTFSSFVRYARKRCKPVLTDNARTELVKGYLEMRKIGSENKTHKTISATTRQLES 543
Query: 605 MVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
++R++E +AKM V V EA RL+ +I
Sbjct: 544 LIRISEALAKMQLREKVEARDVKEAIRLVTSAI 576
Score = 46.8 bits (106), Expect = 0.002
Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 3/78 (3%)
Query: 151 VQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVIL 210
V+GT T+P C P C L S ++D Q IR+QE+ +P G P++L ++
Sbjct: 143 VRGTL-TVPAKC--PHCKKTGTLQLIHTLSYYIDKQIIRLQESPEAIPAGETPQTLHLLA 199
Query: 211 RAEAVESVQAGDRYDFTG 228
V+S + GDR + TG
Sbjct: 200 FDSLVDSAKPGDRIEVTG 217
>UniRef50_Q9LPD9 Cluster: T12C22.19 protein; n=18; Eukaryota|Rep:
T12C22.19 protein - Arabidopsis thaliana (Mouse-ear
cress)
Length = 936
Score = 249 bits (610), Expect = 2e-64
Identities = 142/354 (40%), Positives = 210/354 (59%), Gaps = 23/354 (6%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
++T ++ ++ E+S+D + +I S+ PSI+G+ ++K + L +FGG K LR
Sbjct: 481 KLTQEDKTQIEELSKDPRIVERIIKSIAPSIYGHEDIKTALALAMFGGQEKNIKGKHRLR 540
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
GDINV ++GDP TAKSQ LK V + RAVYT+GK +SA GLTAAV +D + ++ +E G
Sbjct: 541 GDINVLLLGDPGTAKSQFLKYVEKTGQRAVYTTGKGASAVGLTAAVHKDPVTREWTLEGG 600
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489
AL+LAD G+C IDEFDKM+ D+V+IHEAMEQQ+IS++KAG+ +L AR S++AAANP+G
Sbjct: 601 ALVLADRGICLIDEFDKMNDQDRVSIHEAMEQQSISISKAGIVTSLQARCSVIAAANPVG 660
Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC------NKEE 543
GRYD +KS QNV L+ PI+SRFD+ ++ D + D +A +V+ H K E
Sbjct: 661 GRYDSSKSFAQNVELTDPILSRFDILCVVKDVVDPVTDEMLAEFVVNSHFKSQPKGGKME 720
Query: 544 SYDC--------------VYSRDDLLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXX 588
D V ++ L +Y+ +++ + P + E K L Y
Sbjct: 721 DSDPEDGIQGSSGSTDPEVLPQNLLKKYLTYSKLYVFPKLGELDAKKLETVYANLRRESM 780
Query: 589 XXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642
I R LESM+R++E A+MH +VT V+ A R+L S I ++
Sbjct: 781 NGQGVS--IATRHLESMIRMSEAHARMHLRQYVTEEDVNMAIRVLLDSFISTQK 832
Score = 74.1 bits (174), Expect = 1e-11
Identities = 55/236 (23%), Positives = 109/236 (46%), Gaps = 23/236 (9%)
Query: 13 VKDEVGIRCQKLFQDFLEEF----KEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQN 68
++DEV K F+DFL + E+ +I+Y + E++ +LE+ + + + N
Sbjct: 210 MRDEVRRFIAKKFKDFLLTYVKPKNENGDIEYVRLINEMVSANKCSLEIDYKEFIHVHPN 269
Query: 69 LATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTA 128
+A + + + + I L K++ K YV ++P ++R +
Sbjct: 270 IAIWLADAPQPVLEVMEEVSEKVIFDLHPN--YKNIHTK-IYVRVTNLPVNDQIRNIRQI 326
Query: 129 KIGTLIRISGQIVRTHPVHPELVQ------------GTF----YTIPTICRNPVCANRRR 172
+ T+IRI G + R V P+L Q G F Y+ + C ++
Sbjct: 327 HLNTMIRIGGVVTRRSGVFPQLQQVKYDCNKCGAVLGPFFQNSYSEVKVGSCSECQSKGP 386
Query: 173 FMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
F ++ +++++ ++QK+ IQE+ +P G +PR EVIL + ++ + G+ + TG
Sbjct: 387 FTVNVEQTIYRNYQKLTIQESPGTVPAGRLPRHKEVILLNDLIDCARPGEEIEVTG 442
>UniRef50_P49736 Cluster: DNA replication licensing factor MCM2;
n=45; Fungi/Metazoa group|Rep: DNA replication licensing
factor MCM2 - Homo sapiens (Human)
Length = 904
Score = 247 bits (605), Expect = 8e-64
Identities = 190/642 (29%), Positives = 309/642 (48%), Gaps = 57/642 (8%)
Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83
F++FL + + +++ ++ K +L V+++D+ LA + E +
Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 258
Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143
+ A L +L++ K D +V +P ++R L + LIR SG +
Sbjct: 259 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 315
Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202
V P+L + P C ++ + + + Q E E I
Sbjct: 316 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 369
Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262
++ + I E+ V AG R + I++ D+ PG E+T +G +
Sbjct: 370 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428
Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322
G + T LA V + EL TD++ + +
Sbjct: 429 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 467
Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382
S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +RGDINV + GDP T
Sbjct: 468 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGT 527
Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442
AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID
Sbjct: 528 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 587
Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502
EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV
Sbjct: 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 647
Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546
L+ PI+SRFD+ ++ D + D +AR +V H NKEE +
Sbjct: 648 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 707
Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600
Y ++ L +YI +A+ P + + + + Y ITVR
Sbjct: 708 NTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 765
Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642
+ESM+R+AE A++H +V V+ A R++ +S I ++
Sbjct: 766 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 807
>UniRef50_Q8SRF0 Cluster: DNA REPLICATION LICENSING FACTOR OF THE
MCM FAMILY MCM3; n=1; Encephalitozoon cuniculi|Rep: DNA
REPLICATION LICENSING FACTOR OF THE MCM FAMILY MCM3 -
Encephalitozoon cuniculi
Length = 687
Score = 247 bits (604), Expect = 1e-63
Identities = 135/333 (40%), Positives = 197/333 (59%), Gaps = 4/333 (1%)
Query: 331 NLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQ 390
N+ + PSI G++ VKR + L+L GG G+ +RGDIN+ +VGDPSTAKSQLL+
Sbjct: 271 NMHHLIAPSIFGHDIVKRSIALLLVGGNEVVMRNGSKIRGDINILLVGDPSTAKSQLLRY 330
Query: 391 VSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPG 450
V ++ T+GK SS GLTAAVV D+++ + +EAGA++LAD GV CIDEFDKM G
Sbjct: 331 VLNAAQLSIATTGKGSSGVGLTAAVVLDKDTGEKRLEAGAMVLADRGVVCIDEFDKMSDG 390
Query: 451 DQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMS 510
D+VAIHE MEQQT+++AKAG+ TLNAR S+LAAANPI G+Y ++ Q NV L +++
Sbjct: 391 DRVAIHEVMEQQTVTIAKAGIHTTLNARCSVLAAANPIWGQYKESRPPQDNVRLPESLLT 450
Query: 511 RFDLFFILIDESSEMVDYAIARKIVDLHCNKE--ESYDCVYSRDDLLRYIAFARSFKPVI 568
RFDL F+ +D+S+ +D ++ ++ +H + E ++ YI + R KPV+
Sbjct: 451 RFDLIFVTLDKSNTDIDQLVSGHVLRMHMLTQGYEEEGMGVKQEVFRAYIRYCRQKKPVL 510
Query: 569 TEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHE 628
+ EA L+ Y IT R LE+M+RLA AK+ S V
Sbjct: 511 SREAAGLIAREYTSLRQSKDRKEQIV-SITPRMLETMIRLATANAKLRLSDVVEYDDAEC 569
Query: 629 AYRLLNKSII-RVEQPDIHLDEDEPQCEPSMDV 660
A L+ S+ ++ +P + P+ + D+
Sbjct: 570 AVNLVKDSLFQKIVKPAKRIKAAAPEEQDEFDL 602
Score = 41.5 bits (93), Expect = 0.086
Identities = 19/49 (38%), Positives = 30/49 (61%)
Query: 180 SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
S + D+Q + +QE + P G +PRS+EVIL + V+ ++ GDR G
Sbjct: 174 SEYFDYQTVVLQEMPEKAPPGQLPRSVEVILSFDLVDGLKPGDRAKIYG 222
>UniRef50_A2DN04 Cluster: MCM2/3/5 family protein; n=1; Trichomonas
vaginalis G3|Rep: MCM2/3/5 family protein - Trichomonas
vaginalis G3
Length = 842
Score = 246 bits (602), Expect = 2e-63
Identities = 133/333 (39%), Positives = 203/333 (60%), Gaps = 5/333 (1%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRG 370
+T++E + + ++S+ NL + ++ P+IHG+ ++K + + LFGG + +G T+RG
Sbjct: 412 ITEEEKEHIIKLSQSDNLEERIFNAIAPAIHGHRDIKAAIAMSLFGGT-RVEEKGHTVRG 470
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGA 430
DIN+ ++GDP TAKSQ L+ +I PR++YT+GK +SA GLTAA+ RD S ++ IE GA
Sbjct: 471 DINIILLGDPGTAKSQFLQYARDIAPRSIYTTGKGASAVGLTAALHRDHASGEWTIEGGA 530
Query: 431 LMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGG 490
L+LAD GVC IDEFDKM D+ ++HEAMEQQTIS++K G+ TL AR SI+AA NPI
Sbjct: 531 LVLADGGVCLIDEFDKMTDKDRNSLHEAMEQQTISISKGGIVTTLQARCSIIAACNPIRD 590
Query: 491 RYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYS 550
RY + S +N L+ PI++RFD+ ++ D ++ D +A+ + H E+ + S
Sbjct: 591 RYQPSLSFLENSGLTEPILTRFDVICVVRDIINQEADENLAKFVCRNHQGYEQPAGDI-S 649
Query: 551 RDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLA 609
RD L +YI++AR + IT L Y ITVR ESM+RLA
Sbjct: 650 RDLLKKYISYARANVHTRITGADRNKLSNLYTDLRKESEHNGGQS--ITVRNFESMIRLA 707
Query: 610 EGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642
E A+M+ +V + A +L+ +S + ++
Sbjct: 708 EAHARMYLRNNVNDDDTNFAIKLVIESFLSTQK 740
Score = 72.9 bits (171), Expect = 3e-11
Identities = 58/234 (24%), Positives = 109/234 (46%), Gaps = 26/234 (11%)
Query: 14 KDEVGIRCQKLFQDFLEEFKEDN-EIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATT 72
+ E+ I + F+ F++EFK+ N ++ Y + +++ L + EVS+ D+ +N +
Sbjct: 149 RQEIKIEIARKFRIFIQEFKDSNGQLIYLEKIRKVATNNLESFEVSYLDLSHHNTIIGVW 208
Query: 73 IIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGT 132
+ + I P L+ A L L M +L ++ V +P +R+L + +
Sbjct: 209 LGDAPDIIIPILSDAAL-----LVVRKMYPNLDIRKITVRITHLPIIDNIRDLRQIHLDS 263
Query: 133 LIRISGQIVRTHPVHPELVQ------------GTFYTI------PTICRNPVCANRRRFM 174
L+R G + R + + P L+Q G F P C C ++ F
Sbjct: 264 LVRTKGVVTRCNDILPHLLQIKWRCEKCGQVHGPFEVSDEKIYPPAFC--AACNSKGPFR 321
Query: 175 LDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
++ +++ ++Q+I IQE +P G +PR+ EVIL + +V+ G+ D TG
Sbjct: 322 MEDGATLYRNYQRITIQEPPNSVPPGRLPRTKEVILLDDNAGTVRPGEEIDVTG 375
>UniRef50_A7AS39 Cluster: DNA replication licensing factor MCM5,
putative; n=1; Babesia bovis|Rep: DNA replication
licensing factor MCM5, putative - Babesia bovis
Length = 777
Score = 246 bits (601), Expect = 2e-63
Identities = 134/323 (41%), Positives = 191/323 (59%), Gaps = 5/323 (1%)
Query: 314 KEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDIN 373
+E + + ++ ++++ + S+ P+I+G VK+ V LFGG K + +RGDIN
Sbjct: 368 EETNDLVLLATQPDIHDKIFRSIAPAIYGMENVKKAVACALFGGSRKEVGKDNRVRGDIN 427
Query: 374 VCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALML 433
+ ++GDPS AKSQ+LK V + P +VYTSGK SSAAGLTAAVVRD+ F +E GA++L
Sbjct: 428 ILMLGDPSVAKSQILKFVDHVAPISVYTSGKGSSAAGLTAAVVRDKMGV-FSLEGGAMVL 486
Query: 434 ADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYD 493
AD GV CIDEFDKM D VAIHEAMEQQTIS++KAG+ LN R +++AAANP G Y
Sbjct: 487 ADGGVVCIDEFDKMREDDAVAIHEAMEQQTISISKAGITTMLNTRCAVIAAANPTFGSYS 546
Query: 494 RAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDD 553
+ I+SRFDL F+L D+ + D + + I+ LH N+ ++ C
Sbjct: 547 DDTDTSEQHEFKTTILSRFDLIFLLRDKENVRRDSTLCKHILSLHANQSQTEICPIPMMK 606
Query: 554 LLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWR---ITVRQLESMVRLA 609
L R I +A+ + P+++ +A L +Y + IT+RQLES+VR+A
Sbjct: 607 LRRLIQYAKQAVSPMLSSDAKDTLRNFYVQKRREYREDKRNATKKIPITLRQLESLVRIA 666
Query: 610 EGVAKMHCSGHVTPAHVHEAYRL 632
E A+M S T H+ A L
Sbjct: 667 ESFARMELSPISTEKHIQMAIEL 689
>UniRef50_Q5CNK7 Cluster: DNA replication licensing factor MCM2;
n=2; Cryptosporidium|Rep: DNA replication licensing
factor MCM2 - Cryptosporidium hominis
Length = 970
Score = 245 bits (600), Expect = 3e-63
Identities = 124/248 (50%), Positives = 170/248 (68%), Gaps = 6/248 (2%)
Query: 300 HDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVA 359
HD +D +TD+++ K+ E+SRD ++ +++S+ PSI+G+N +K + LF GV
Sbjct: 477 HDALRKD---DLTDEDYKKIKELSRDPDIKEKIVSSIAPSIYGHNHIKTAIACSLFSGVR 533
Query: 360 KTTIEGTT--LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVR 417
K +EG +RGDINV IVGDP AKSQ LK V + R +YTSGK +SA GLTA+V R
Sbjct: 534 KQ-VEGKHHHIRGDINVLIVGDPGLAKSQFLKYVEKSFDRTIYTSGKGASAVGLTASVRR 592
Query: 418 DEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNA 477
D S ++ +E GAL+LAD G+C IDEFDKM D+V+IHEAMEQQ+IS++KAG+ TL A
Sbjct: 593 DPISGEWTLEGGALVLADEGICLIDEFDKMSDKDRVSIHEAMEQQSISISKAGIVTTLRA 652
Query: 478 RTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDL 537
R SI+AAANPI G+YD + + + NV L+ PI+SRFD+ +L DE M D +A +V
Sbjct: 653 RCSIIAAANPIFGKYDSSLTFKDNVDLTDPIISRFDVLAVLKDEVHPMKDELLANFVVQS 712
Query: 538 HCNKEESY 545
H N +E Y
Sbjct: 713 HMNSQEMY 720
Score = 48.8 bits (111), Expect = 6e-04
Identities = 19/62 (30%), Positives = 39/62 (62%)
Query: 167 CANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDF 226
C ++ F+++ +K+++ ++QK+ IQE+ +P G +PRS E+I+ + V+ G+
Sbjct: 384 CQSKGPFVINREKTIYENYQKLTIQESPGSVPAGRVPRSREIIVSGDLVDYACPGEEIIV 443
Query: 227 TG 228
TG
Sbjct: 444 TG 445
Score = 39.5 bits (88), Expect = 0.35
Identities = 27/90 (30%), Positives = 45/90 (50%), Gaps = 3/90 (3%)
Query: 554 LLRYIAFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612
L +YI +AR + KP I + ++ +Y +TVR +ES++RLAE
Sbjct: 757 LCKYIRYARKYCKPQIRSVDKEKIITFYSRIRQEAQQTGGIS--MTVRHIESIIRLAEAQ 814
Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642
AKM S V+ V A ++ +S I+ ++
Sbjct: 815 AKMRLSPVVSNKDVDGAIGMVLESFIQSQK 844
>UniRef50_Q8TJF6 Cluster: Mcm protein; n=5; Methanosarcinaceae|Rep:
Mcm protein - Methanosarcina acetivorans
Length = 702
Score = 244 bits (598), Expect = 6e-63
Identities = 193/628 (30%), Positives = 309/628 (49%), Gaps = 98/628 (15%)
Query: 50 PELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKEC 109
P+ +L ++F +VEK+++ LA ++ + P + +L E + D K+
Sbjct: 33 PDTRSLYINFINVEKFDRYLARDLLNNPGELIP-------EFETNLKEIDLPVDKILKDA 85
Query: 110 YVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTI----------P 159
+V ++VPTR + EL + +G LI I G + + V P + + F + P
Sbjct: 86 HVRIMNVPTRVPIGELRSKHLGKLISIEGMVRKATEVRPRITKAAFQCLRCEHITFVDQP 145
Query: 160 TI--------CRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILR 211
+ C N C + + + + S+FVD Q+ Q + P P L R
Sbjct: 146 SFKFEEPFSGCENETCGKKGPYKVRIEDSIFVD-----AQKLQVQEP----PEDL----R 192
Query: 212 AEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGV 271
+++ D TG L +PG R +T GI + +
Sbjct: 193 GTQAQNLDISIEEDLTG----------LILPGERVILT------------GILMSRQRTI 230
Query: 272 RELHYKTAFLACSVQAVS-RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYN 330
R+ K+ F ++ S R GTA ++T ED +K +T ++RD +Y+
Sbjct: 231 RD--GKSTFYDIFLEVNSIERMGTA-FDEIEITPEDEKKILT---------LARDPAVYD 278
Query: 331 NLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQ 390
+I+S+ P I+G ++VK L LF GV K +G+ LRGDI++ VGDPS K++L+K
Sbjct: 279 KVISSIAPLIYGMDDVKEATALQLFSGVPKNAPDGSYLRGDIHLLCVGDPSKGKTKLMKS 338
Query: 391 VSEITPRAVYTSGKASSAAGLTAAVVRDEESFD--FVIEAGALMLADNGVCCIDEFDKMD 448
+PRAV+TS KA++A GLTA V +DE+ + + +E GAL++AD GV +DE DKM
Sbjct: 339 SQARSPRAVFTSRKATTAGGLTAIVTKDEKFGEGRWAVEGGALVMADKGVAYVDEADKMR 398
Query: 449 PGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPI 508
GD+ A+HEAMEQQ I+LAKAG+ ATL RT++ +ANP G++D + L + + + P +
Sbjct: 399 QGDRDALHEAMEQQEINLAKAGIIATLKTRTAVFMSANPKYGKFDTYEGLAEQINMPPSL 458
Query: 509 MSRFDLFFILIDESSEMVDYAIARKIVDLHC------NKEESYDCVYSRDDLL------- 555
+SRFDL F+L+D + + D I+ ++ H +E D +S ++L
Sbjct: 459 LSRFDLIFVLLDTPNAVEDARISEHVLGTHTAGEMRQQRETVSDSAFSTEELAEASTHVR 518
Query: 556 ---------RYIAFA-RSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESM 605
+++A+A R+ PV+T EA + +Y IT RQ E+
Sbjct: 519 PEIPPDLFRKHVAYARRNIFPVLTTEARDHIHHFYLDLRKTGQSSKIKSIPITTRQEEAT 578
Query: 606 VRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
VRLAE A++ S VT A RL+
Sbjct: 579 VRLAEASARVRLSQGVTLDDAKRATRLM 606
>UniRef50_P24279 Cluster: DNA replication licensing factor MCM3;
n=6; Saccharomycetales|Rep: DNA replication licensing
factor MCM3 - Saccharomyces cerevisiae (Baker's yeast)
Length = 971
Score = 244 bits (597), Expect = 7e-63
Identities = 157/439 (35%), Positives = 232/439 (52%), Gaps = 61/439 (13%)
Query: 123 RELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYT---------------------IPTI 161
R LT + L+ + G + +T V P+L++ Y IPT
Sbjct: 169 RTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTP 228
Query: 162 CRNPV-CANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQA 220
P + + S F+D Q+I +QE P G +PRS++
Sbjct: 229 AIYPTEDTEGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSID------------- 275
Query: 221 GDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAF 280
+I+ D+ + PG R + K G M +G +KT
Sbjct: 276 ---------VILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIG-----FKTLI 321
Query: 281 LACSVQAVSRRFGTAELPTHDLTTEDMRKQM-TDKEWDKVYEMSRDRNLYNNLITSLFPS 339
L G P H +T +QM TD + + ++S+ +++++ L SL PS
Sbjct: 322 L-----------GNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPS 370
Query: 340 IHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAV 399
I+G++ +K+ +LLML GGV K G+ LRGDIN+ +VGDPSTAKSQLL+ V A+
Sbjct: 371 IYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAI 430
Query: 400 YTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAM 459
T+G+ SS GLTAAV D E+ + +EAGA++LAD GV CIDEFDKM D+VAIHE M
Sbjct: 431 ATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVM 490
Query: 460 EQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILI 519
EQQT+++AKAG+ TLNAR S++AAANP+ G+YD + QN+AL ++SRFDL F++
Sbjct: 491 EQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVT 550
Query: 520 DESSEMVDYAIARKIVDLH 538
D+ +E+ D +I+ ++ H
Sbjct: 551 DDINEIRDRSISEHVLRTH 569
>UniRef50_Q236A7 Cluster: MCM2/3/5 family protein; n=1; Tetrahymena
thermophila SB210|Rep: MCM2/3/5 family protein -
Tetrahymena thermophila SB210
Length = 855
Score = 242 bits (592), Expect = 3e-62
Identities = 115/247 (46%), Positives = 172/247 (69%)
Query: 302 LTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT 361
L+ E+ Q+T ++ + ++S+ ++L + + S+ PSI+G+ ++K+ +LL L GG KT
Sbjct: 278 LSQENDDVQLTTEDLQYIKKISKRKDLVDIFVNSIAPSIYGHQQIKKALLLQLLGGTEKT 337
Query: 362 TIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEES 421
+GT LRGDIN+ ++GDPSTAKSQ+L+ + P A+ T+G+ SS GLTAAV D E+
Sbjct: 338 VGQGTHLRGDINIMMIGDPSTAKSQVLRYMLATAPLALNTTGRGSSGVGLTAAVKTDRET 397
Query: 422 FDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSI 481
+ +EAGA++LAD GV CIDEFDKM D+VAIHE MEQQT+++AKAG+ +LNAR S+
Sbjct: 398 GERHLEAGAMVLADKGVVCIDEFDKMSEEDRVAIHEVMEQQTVTIAKAGIHCSLNARCSV 457
Query: 482 LAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNK 541
LAAANPI G Y R ++ +N+ L ++SRFDL FI++DE +D IA ++ H +
Sbjct: 458 LAAANPIYGEYHRDQTPTKNIGLPDSLLSRFDLLFIVLDEKDPDIDRLIAERVTRNHRYR 517
Query: 542 EESYDCV 548
E+Y+ +
Sbjct: 518 PENYEII 524
Score = 46.8 bits (106), Expect = 0.002
Identities = 23/54 (42%), Positives = 31/54 (57%)
Query: 175 LDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
L+ S F DFQ I +QE P G +PRS++V+L + V SV+ GDR G
Sbjct: 197 LEYGYSKFKDFQTIIVQELPENAPNGLLPRSIDVVLEEDLVGSVKPGDRVRIYG 250
Score = 35.1 bits (77), Expect = 7.5
Identities = 34/134 (25%), Positives = 61/134 (45%), Gaps = 12/134 (8%)
Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSF--KPVITEEAGKLLVEYYXXXXXXXXXXXXXX 594
LH +K++ + +++ L +YIA+A+ P +++E+ + + YY
Sbjct: 562 LHGDKKKE---ILNQNFLKKYIAYAKKTFNSPKLSDESIEYINLYYNQLRQKNFQDSTTN 618
Query: 595 WRI-----TVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDE 649
+ T R LE+++RLA AK+ S ++ + A LLN ++ E D E
Sbjct: 619 GGVKVLPVTTRTLETVIRLATASAKLRLSKNIEISDCRLATSLLNYALFNKE--DAIRPE 676
Query: 650 DEPQCEPSMDVDQD 663
+E E D QD
Sbjct: 677 EEEFYEEDEDYKQD 690
>UniRef50_Q5CTW9 Cluster: DNA replication licensing factor MCM4 like
AAA+ ATpase; n=2; Cryptosporidium|Rep: DNA replication
licensing factor MCM4 like AAA+ ATpase - Cryptosporidium
parvum Iowa II
Length = 896
Score = 241 bits (591), Expect = 4e-62
Identities = 122/274 (44%), Positives = 180/274 (65%), Gaps = 9/274 (3%)
Query: 369 RGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEA 428
R +IN+ + GDPSTAKSQLL+ + +ITPR Y SGK SSA GLTA + +D E+ + V+E+
Sbjct: 518 RSEINILLCGDPSTAKSQLLQYIHKITPRGYYISGKGSSAVGLTAYITKDPETKEIVLES 577
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPI 488
GAL+L+D G+CCIDEFDKMD + +HEAMEQQT+S+AKAG+ +LNAR +ILA+ANPI
Sbjct: 578 GALVLSDRGICCIDEFDKMDDSSRSILHEAMEQQTVSIAKAGIICSLNARVAILASANPI 637
Query: 489 GGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH----CNKEES 544
RYD KS+ +N+ L P +MSRFDL ++++D+ SE D +A + L+ N++ +
Sbjct: 638 SSRYDPKKSVVENINLPPSLMSRFDLIYLMLDKQSEESDKRLAEHLCALYTSYNSNEKPA 697
Query: 545 YDCVYSRDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITV---- 599
++ + L RYI++ R + P ++ +A LV+ Y + T+
Sbjct: 698 SSAIFDKVTLSRYISYCRQNCNPKLSTDACNKLVQNYISMRRQGSTGGSLQRQKTITATP 757
Query: 600 RQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
RQLES++R++E +A+M S V +HV EA RL+
Sbjct: 758 RQLESLIRISESLARMELSEWVKKSHVDEATRLM 791
Score = 62.5 bits (145), Expect = 4e-08
Identities = 53/209 (25%), Positives = 91/209 (43%), Gaps = 13/209 (6%)
Query: 159 PTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESV 218
PT+C PVC N F L + F + Q ++IQE +P G P ++ + E V+
Sbjct: 294 PTLC--PVCNNNYSFELMHNLCQFSNKQILKIQELPDTIPPGETPHTILGYVYDEMVDCC 351
Query: 219 QAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKT 278
+ GDR +F G + V G R R ++ I + L+
Sbjct: 352 RPGDRIEFNGIVKV---------SGVRQVAKRRQLMSVFRTYIDILHVNKNTCNMLYSVV 402
Query: 279 AFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFP 338
A + + G + ++ + + T + ++ + MS+D LY+ L S+ P
Sbjct: 403 GNSAGEMSEIDN--GIQSIDGQNINSVEKNNLFTKEMIEQFHAMSKDPMLYDKLSRSIAP 460
Query: 339 SIHGNNEVKRGVLLMLFGGVAKTTIEGTT 367
SI N++VK+G+L LFGG K ++ +
Sbjct: 461 SIWENDDVKKGLLCQLFGGSRKNLLKAAS 489
>UniRef50_Q9U1E0 Cluster: DNA replication licensing factor (CDC47
homolog) (Minichromosome maintenance (MCM) complex
subunit, putative); n=6; Trypanosomatidae|Rep: DNA
replication licensing factor (CDC47 homolog)
(Minichromosome maintenance (MCM) complex subunit,
putative) - Leishmania major
Length = 725
Score = 238 bits (583), Expect = 4e-61
Identities = 201/665 (30%), Positives = 311/665 (46%), Gaps = 64/665 (9%)
Query: 7 YATQSQVKDEVGIRCQKLFQDFLEEFKEDN-EIKYEKHAKELLKPELSTLEVSFDDVEKY 65
YA + K I + + + FLEEF++ + KY A + + + + DDV +
Sbjct: 9 YAAAASSKYPNYINDRDVCKRFLEEFRDSTGQAKYVIQAHHIAQRQSIVFSIFLDDVAGF 68
Query: 66 NQ-NLATTI-------IEEYYR----IYPFLNRAIL---NYILSLAETGMKKDLQDKECY 110
Q +LA + +EE YR I P +R + I+ +G + Y
Sbjct: 69 GQLHLAQRVQMNVVGYMEELYRVVDSIIPQTDRVVDMVDQLIMEARMSGQELPALLTRRY 128
Query: 111 VSFVDVPTRHKV----RELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPV 166
+ + V REL KIGTL + G + V P+L + ++C V
Sbjct: 129 ELKIHPLSEDSVPIPLRELKGGKIGTLTVLRGICIAATAVRPKLSM-----LVSVCE--V 181
Query: 167 CANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDF 226
CA + D+ +++ ++Q + R L A +Y
Sbjct: 182 CAETTFQQVIGDR-----LTPLQVCQSQRCKLNNAVGRLL-------AQNKASKFMKYQE 229
Query: 227 TGTLIVVPDVGALSMPGSRAEITT--RTKLANEGQMEGIKGLKALGVRELHYKTAFLACS 284
+ DV ++P + + +T++A GQ+ I G+ AF A +
Sbjct: 230 LRVQELPEDVPRGAIPRTIRVVCEGEQTRIATPGQVVRITGVYCPDPSTGQGHEAFRAST 289
Query: 285 VQAVSRRFGTAELP--THDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHG 342
+ + EL ++ EDMR Q+ D + + + L S+ P I G
Sbjct: 290 MVKTLYKAIHIELEKRSYQEAAEDMRAQVED-----IRDYPDREAVIEKLTRSIAPEIWG 344
Query: 343 NNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTS 402
+VK+ +L L GG + G +R DIN+ +GDP AKSQLLK ++ + PR+V+T+
Sbjct: 345 MEDVKKALLCQLVGG--SSIANGIRIRSDINILFMGDPGVAKSQLLKWIASVAPRSVFTT 402
Query: 403 GKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQ 462
GK SS GLTAAV D + + ++E GAL+L+D GVCCIDEFDKMD D+ A+HE MEQQ
Sbjct: 403 GKGSSGVGLTAAVTHDTHTGEVMLEGGALVLSDKGVCCIDEFDKMDDSDRTALHEVMEQQ 462
Query: 463 TISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDES 522
+S+AKAG+ +LNARTSILAAANP GR+ R + +NV L P ++SRFDL ++L+DES
Sbjct: 463 MVSIAKAGIITSLNARTSILAAANPKFGRWKRNATPTENVNLPPALLSRFDLLWLLLDES 522
Query: 523 SEMVDYAIARKIVDLHCN----KEESYDCV-------YSRDDLLRYIAFARSFKPVITEE 571
S D ++ + +H + + D V + RD L Y+ + P +
Sbjct: 523 SRERDAELSMHVTHVHLHGVAPGTVADDGVRGTTTEYFGRDFLRAYVGEVKRIHPYVDPG 582
Query: 572 AGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYR 631
A K + + Y +T R L S++RL++ A++ S V V EA R
Sbjct: 583 AAKAISDIYCEMRAQSARHSNV---VTARTLLSLIRLSQACARLRFSERVLEEDVREAGR 639
Query: 632 LLNKS 636
LL+ S
Sbjct: 640 LLDCS 644
>UniRef50_Q54CP4 Cluster: MCM family protein; n=1; Dictyostelium
discoideum AX4|Rep: MCM family protein - Dictyostelium
discoideum AX4
Length = 757
Score = 237 bits (581), Expect = 6e-61
Identities = 115/227 (50%), Positives = 162/227 (71%), Gaps = 2/227 (0%)
Query: 312 TDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGD 371
T E SR ++L N + +S+ PSI+G+ ++KR + LFGG +K + LRGD
Sbjct: 303 TPSEEQSFKVFSRRQDLRNIIASSIAPSIYGHEDIKRAISCQLFGGSSKKLPDKMRLRGD 362
Query: 372 INVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGAL 431
IN+ ++GDP TAKSQLLK V ++ P +VYTSGK SSAAGLTA+V+R+ + ++ +E GA+
Sbjct: 363 INLLLLGDPGTAKSQLLKFVEKVAPISVYTSGKGSSAAGLTASVIREPSTGEYYLEGGAM 422
Query: 432 MLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGR 491
++AD GV CIDEFDKM+ D+VAIHEAMEQQTIS+AKAG+ LN+RTS+LAAANP+ GR
Sbjct: 423 VVADGGVVCIDEFDKMNVDDRVAIHEAMEQQTISIAKAGITTILNSRTSVLAAANPVYGR 482
Query: 492 YDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
Y+ A N+ I+SRFDL FI+ D +E D+ I++ ++++H
Sbjct: 483 YNDA--ADDNINFQSTILSRFDLIFIVKDPKNEKRDFIISKHVINIH 527
Score = 56.4 bits (130), Expect = 3e-06
Identities = 72/294 (24%), Positives = 119/294 (40%), Gaps = 38/294 (12%)
Query: 24 LFQDFLEEFKE-DNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYP 82
LF+ F+ E+K+ DN Y++ ++ +EVS D + +NQ L+ I + P
Sbjct: 35 LFKRFINEWKDQDNVFIYKEQLRQHYNLGWHYIEVSIDHLTDFNQELSGRFISSPNELMP 94
Query: 83 FLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIV- 141
AI + I E K+ D++ + F +R L I L+++ G ++
Sbjct: 95 SFEDAIKDII---KEMNYNKEQVDEDIQILFKSSANPEPIRYLRAGLISKLVKVQGIVIS 151
Query: 142 --RTHPVHPELV--------QGTFYTIPTICRNPV--------------CANRRRFMLDA 177
RT P +V T + P I + + C N +L +
Sbjct: 152 ASRTQPKPSTMVVKCKNCQHTQTLHIRPGIVSSVLPQQCERGSNDAGKPCPNNPYVVL-S 210
Query: 178 DKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVG 237
D+S FV+ Q +++QE+ +P G +PR + + L + + G R G L G
Sbjct: 211 DQSTFVNQQILKLQESPETIPTGEMPRHIILSLDKSLADKITPGTRIKVLGVL------G 264
Query: 238 ALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRR 291
G R EI T N ++ GI A G +H+ T S + SRR
Sbjct: 265 IFEGGGKRREIAGGTIRTNYLRVLGITSDNA-GRDSMHF-TPSEEQSFKVFSRR 316
Score = 40.3 bits (90), Expect = 0.20
Identities = 20/40 (50%), Positives = 27/40 (67%)
Query: 597 ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKS 636
ITVRQLE+++R++E +AKM S T H EA RL + S
Sbjct: 633 ITVRQLEAIIRISESLAKMSLSPIATNEHAKEAIRLFDIS 672
>UniRef50_Q4WK28 Cluster: DNA replication licensing factor Mcm3,
putative; n=19; Eukaryota|Rep: DNA replication licensing
factor Mcm3, putative - Aspergillus fumigatus (Sartorya
fumigata)
Length = 892
Score = 237 bits (581), Expect = 6e-61
Identities = 112/228 (49%), Positives = 162/228 (71%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRG 370
+TD + + ++++ +N++ L SL PSI+G++ +K+ +LLML GG+ K GT LRG
Sbjct: 289 ITDTDIRNINKVAKKKNVFELLANSLAPSIYGHDYIKKAILLMLLGGMEKNLDNGTHLRG 348
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGA 430
DIN+ +VGDPSTAKSQLL+ V P A+ T+G+ SS GLTAAV D+E+ + +EAGA
Sbjct: 349 DINILMVGDPSTAKSQLLRFVLNTAPLAIATTGRGSSGVGLTAAVTSDKETGERRLEAGA 408
Query: 431 LMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGG 490
++L D GV CIDEFDKM D+VAIHE MEQQT+++AKAG+ +LNAR S+LAAANPI G
Sbjct: 409 MVLGDRGVVCIDEFDKMSDVDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVLAAANPIYG 468
Query: 491 RYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
+YD K +N+AL ++SRFDL F++ D+ + D ++ ++ +H
Sbjct: 469 QYDPHKDPHKNIALPDSLLSRFDLLFVVTDDIEDARDRMVSEHVLRMH 516
Score = 55.2 bits (127), Expect = 7e-06
Identities = 54/243 (22%), Positives = 100/243 (41%), Gaps = 26/243 (10%)
Query: 12 QVKDEVGIRCQKLFQDFLEEFKEDNEIKYEKHAKEL---LKPELSTLEVSFDDVEKYNQN 68
Q++DE G + +FL+ + + + ++ L L L VS D++ +N+
Sbjct: 5 QLRDEAGQDRVRAAVEFLDPKVLTGDARARSYRADIVLMLNRGLRRLTVSIDEIRAHNRE 64
Query: 69 LATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKV--RELT 126
LA ++ + +RA+ I +L ++ D Y ++V R L
Sbjct: 65 LADGLLTSPFDYSLAFDRALKEVIKTLPNRPSRETADDVNYYCAYVGAFGEFSCNPRTLG 124
Query: 127 TAKIGTLIRISGQIVRTHPVHPELVQGTFYT------IPTICRNPVCA-----NRRRFML 175
+ + +I + G + + V P+++Q Y + R+ N +
Sbjct: 125 STHLNRMISLEGIVTKCSLVRPKIIQSVHYNERKDRFVARRYRDQTMTTTGITNMNVYPQ 184
Query: 176 DADK----------SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYD 225
+ D+ S ++D Q I IQE P G +PRS++VIL + V+S + GDR
Sbjct: 185 EDDEKNPLITEYGYSTYLDHQTISIQEMPERAPAGQLPRSVDVILDDDLVDSAKPGDRIQ 244
Query: 226 FTG 228
G
Sbjct: 245 LVG 247
>UniRef50_Q4DRN3 Cluster: Minichromosome maintenance (MCM) complex
subunit, putative; n=3; Trypanosoma|Rep: Minichromosome
maintenance (MCM) complex subunit, putative -
Trypanosoma cruzi
Length = 872
Score = 237 bits (580), Expect = 8e-61
Identities = 145/385 (37%), Positives = 213/385 (55%), Gaps = 25/385 (6%)
Query: 159 PTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESV 218
PT C + C + + + S+F D Q +R+QE L G P ++ V++ ++V++V
Sbjct: 260 PTRCDH--CGKNYSYRIQHNLSLFDDKQLVRLQEAPEHLSDGETPVTISVVVYGDSVDAV 317
Query: 219 QAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKT 278
GDR TG P R TTR I+ + A V +H +
Sbjct: 318 VPGDRVVVTGIYRAAP---------VRLNSTTRC----------IRSIFATHVDAVHIEH 358
Query: 279 AFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFP 338
+ ++ T L + ED + + ++ SR ++Y+ L+ S
Sbjct: 359 RRAGRHLWKKQQQPLTPSLEAEEGLAEDPTEAARRDVFRRI--ASRP-DIYDILLNSFAR 415
Query: 339 SIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRA 398
+I GN +VKRG+L LFGG K GT R +INV + GDP AKSQLL QV EI PR
Sbjct: 416 TIWGNEDVKRGILSQLFGGTRKELKSGT-FRAEINVILCGDPGVAKSQLLSQVHEIAPRG 474
Query: 399 VYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEA 458
VYTSGK SS+ GLTA VV++ E+ + V+E GAL+L+D G+CCIDEFDKM+ + +HE
Sbjct: 475 VYTSGKGSSSVGLTAFVVQNHETGELVLEPGALVLSDRGLCCIDEFDKMNEATRSVLHEV 534
Query: 459 MEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFIL 518
MEQQT+S+AKAG+ A LNARTS+LAAANP +++ ++ +N+ + P ++SRFDL F+L
Sbjct: 535 MEQQTLSIAKAGIIAQLNARTSVLAAANPKESQWNVNLNVVENLQIEPTLLSRFDLIFLL 594
Query: 519 IDESSEMVDYAIARKIVDLHCNKEE 543
+D D +A ++ L +E
Sbjct: 595 LDRHDPTEDRRLASHVLSLFMEPDE 619
Score = 43.6 bits (98), Expect = 0.021
Identities = 31/85 (36%), Positives = 41/85 (48%), Gaps = 3/85 (3%)
Query: 554 LLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612
L +YIA AR + P +TE + K L Y T+RQLESM+RLAE
Sbjct: 687 LSQYIALARETVHPRLTEASHKQLATSYVEMRRARGSSRTVS--ATLRQLESMIRLAEAR 744
Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSI 637
KM VT V EA L++ ++
Sbjct: 745 CKMRFGAEVTVEDVKEAKWLISAAL 769
>UniRef50_A7D0S9 Cluster: MCM family protein; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: MCM family protein -
Halorubrum lacusprofundi ATCC 49239
Length = 700
Score = 237 bits (579), Expect = 1e-60
Identities = 137/342 (40%), Positives = 206/342 (60%), Gaps = 28/342 (8%)
Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364
EDM +T+ + ++ E+S ++Y+ ++ S+ P+I+G E K ++L LF GV K +
Sbjct: 256 EDM--DITEADKREIIELSNREDIYDAMVESIAPAIYGYEEEKLAMILQLFSGVTKHLPD 313
Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE--ESF 422
G+ +RGD+++ ++GDP T KSQ++ V I PR+VYTSGK SSAAGLTAA VRD+ +
Sbjct: 314 GSRIRGDLHMLLIGDPGTGKSQMISYVENIAPRSVYTSGKGSSAAGLTAAAVRDDFGDGQ 373
Query: 423 DFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSIL 482
+ +EAGAL+LAD G+ +DE DKMD D+ A+HE +EQQ IS++KAG+ ATL AR S+L
Sbjct: 374 QWSLEAGALVLADKGIAAVDELDKMDSSDRSAMHEGLEQQKISVSKAGINATLKARCSLL 433
Query: 483 AAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIV------D 536
AANP GR+D+ + + + + L P ++SRFDL F + D D +A+ I+ +
Sbjct: 434 GAANPKYGRFDQYEPIGEQIDLEPALISRFDLIFTVTDSPDPDHDSRLAKHIIKTNYAGE 493
Query: 537 LHCNKEESYDCVYSRD---------------DLLR-YIAFA-RSFKPVITEEAGKLLVEY 579
++ +EE ++ + +LLR YIA A RS P +TEEA L+ E+
Sbjct: 494 INTQREELASSEFTPEQVAEVTQEVAPEIDAELLRKYIAHAKRSCYPTMTEEAKDLIEEF 553
Query: 580 YXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHV 621
Y +T R+LE+MVRLAE A++ S V
Sbjct: 554 YVNLRSKGADEDAPV-PVTARKLEAMVRLAEASARVRLSDTV 594
Score = 46.8 bits (106), Expect = 0.002
Identities = 49/197 (24%), Positives = 87/197 (44%), Gaps = 24/197 (12%)
Query: 51 ELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECY 110
E +L + +DD+ +++++LA E +R P R L L + + D+ +
Sbjct: 35 EQRSLYIEYDDLYQFDRDLA-----EDFRTKPEQMREYAEEALRLYD--LPADVSLGRAH 87
Query: 111 VSFVDVPTRHKVRELTTAK--IGTLIRISGQIVRTHPVHPELVQGTFY-----TIPTICR 163
V ++P +R + IG L+ I G + + V P++ + F TI I +
Sbjct: 88 VRIENLPESIDIRGIRVHDDHIGKLVSIKGIVRKATDVRPKVTEAAFECQRCGTITYIPQ 147
Query: 164 NPV----------CANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAE 213
+ C + F ++ D+S FVD QK+RIQE+ L G P++++V + +
Sbjct: 148 SDGGFQEPHECQGCERQGPFRVNFDQSEFVDSQKLRIQESPEGLRGGETPQNIDVDIVDD 207
Query: 214 AVESVQAGDRYDFTGTL 230
V GD G L
Sbjct: 208 ITGKVSPGDHVTCVGVL 224
>UniRef50_Q9FL33 Cluster: DNA replication licensing factor MCM3
homolog; n=15; Magnoliophyta|Rep: DNA replication
licensing factor MCM3 homolog - Arabidopsis thaliana
(Mouse-ear cress)
Length = 776
Score = 237 bits (579), Expect = 1e-60
Identities = 112/232 (48%), Positives = 165/232 (71%)
Query: 312 TDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGD 371
T ++ D + ++R + ++ L SL PSI+G+ +K+ V+L++ GGV K GT LRGD
Sbjct: 269 TKQDLDNIKNIARRDDAFDLLARSLAPSIYGHAWIKKAVVLLMLGGVEKNLKNGTHLRGD 328
Query: 372 INVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGAL 431
IN+ +VGDPS AKSQLL+ + I P A+ T+G+ SS GLTAAV D+E+ + +EAGA+
Sbjct: 329 INMMMVGDPSVAKSQLLRAIMNIAPLAISTTGRGSSGVGLTAAVTSDQETGERRLEAGAM 388
Query: 432 MLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGR 491
+LAD G+ CIDEFDKM+ D+VAIHE MEQQT+++AKAG+ A+LNAR S++AAANPI G
Sbjct: 389 VLADKGIVCIDEFDKMNDQDRVAIHEVMEQQTVTIAKAGIHASLNARCSVVAAANPIYGT 448
Query: 492 YDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE 543
YDR+ + +N+ L ++SRFDL FI++D+ +D I+ ++ +H K +
Sbjct: 449 YDRSLTPTKNIGLPDSLLSRFDLLFIVLDQMDAGIDSMISEHVLRMHRYKND 500
Score = 48.8 bits (111), Expect = 6e-04
Identities = 37/135 (27%), Positives = 63/135 (46%), Gaps = 5/135 (3%)
Query: 537 LHCNKE--ESYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXX 593
LH K+ +++D + L +YI +A+ P +T+EA + + E Y
Sbjct: 530 LHGKKKRGQTHDKTLTIKFLKKYIHYAKHRITPKLTDEASERIAEAYADLRNAGSDTKTG 589
Query: 594 -XWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEP 652
IT R LE+++RLA AKM S VT A A +L+N +I E ++ D ++
Sbjct: 590 GTLPITARTLETIIRLATAHAKMKLSSEVTKADAEAALKLMNFAIYHQELTEMD-DREQE 648
Query: 653 QCEPSMDVDQDEPNG 667
+ + + P+G
Sbjct: 649 ERQREQAEQERTPSG 663
Score = 36.7 bits (81), Expect = 2.4
Identities = 20/62 (32%), Positives = 30/62 (48%)
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSM 241
+ D Q + IQE G +PRS++VI + V+S + GDR G +P S+
Sbjct: 184 YKDHQTLSIQEVPENAAPGQLPRSVDVIAEDDLVDSCKPGDRVSVFGIYKALPGKSKGSV 243
Query: 242 PG 243
G
Sbjct: 244 NG 245
>UniRef50_Q4QI01 Cluster: Minchromosome maintenance (MCM) complex
subunit, putative; n=3; Leishmania|Rep: Minchromosome
maintenance (MCM) complex subunit, putative - Leishmania
major
Length = 895
Score = 236 bits (578), Expect = 1e-60
Identities = 176/552 (31%), Positives = 278/552 (50%), Gaps = 68/552 (12%)
Query: 43 HAKELLKPEL---STLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYI---LSLA 96
+ KELL+ + STLEV F +++ L + ++ A+ + + + L
Sbjct: 78 YLKELLRMHMQGRSTLEVDFTWLQRVAPRLYVQTVHHPTECLQMMS-AVADEVYRDVLLL 136
Query: 97 ETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPEL------ 150
G++ +D V+ +P+ +++L+ I L+ I G ++R + PE+
Sbjct: 137 RHGIEV-AEDVLITVAAKKLPSMWTLKQLSPQHIEQLLSIKGMVIRVSKIVPEIRVACFQ 195
Query: 151 ----------VQGTFYTI--PTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELP 198
V G I PT C + C F L + S++ D Q I++QE+ +
Sbjct: 196 CWNCQYQERSVSGDKGRIFEPTRCAH--CGKTYSFKLQHNLSLYEDKQLIKVQESPEHVA 253
Query: 199 RGCIPRSLEVILRAEAVESVQAGDRYDFTG----TLI-------VVPDVGALSMPGSRAE 247
G P S+ V++ V++V GDR TG T I ++ + A + E
Sbjct: 254 DGETPISIGVVVYGSMVDAVVPGDRVIVTGVYRSTPIRLNANTRIIKSIFATHIDAVHIE 313
Query: 248 ITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDM 307
+ T+ + G +G LH T LA TA+ DL++ +
Sbjct: 314 LVRATRASEAGAKKGCFANGNATGTGLHVSTPTLA-----------TAKNAEGDLSSAVL 362
Query: 308 RKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTI---- 363
M D + ++ ++Y+ L+ S +I G+++VKRG+L LFGG AKT +
Sbjct: 363 ---MDTARLDMFHSLAHRPDIYDVLLHSFARTIWGHDDVKRGILAQLFGGTAKTFVFSER 419
Query: 364 -----------EGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLT 412
R ++NV + GDP AKSQLL QV EI PR VYTSGK SS+ GLT
Sbjct: 420 IGSGAAATTSSNSAVFRSELNVLLCGDPGVAKSQLLTQVHEIAPRGVYTSGKGSSSVGLT 479
Query: 413 AAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVR 472
A VV+D ++ + V+E GAL+L+D G+CCIDEFDKM+ + +HE MEQQT+S+AKAG+
Sbjct: 480 AFVVQDSDTGELVLEPGALVLSDRGLCCIDEFDKMNEATRSVLHEVMEQQTLSIAKAGII 539
Query: 473 ATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIAR 532
A LNARTSILAAANP +++ ++ +N+ + P ++SRFDL F+L+D + D +A
Sbjct: 540 AQLNARTSILAAANPKDSQWNAQLNVVENLQIEPTLLSRFDLIFLLLDCHDSVEDRRLAA 599
Query: 533 KIVDLHCNKEES 544
++ L+ + S
Sbjct: 600 HVLSLYMDTSRS 611
Score = 45.2 bits (102), Expect = 0.007
Identities = 30/85 (35%), Positives = 43/85 (50%), Gaps = 3/85 (3%)
Query: 554 LLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612
L YIA AR + P +TE + K+L Y T+RQLESM+RL+E
Sbjct: 707 LSEYIALARETIFPKLTEASHKMLARCYVELRQARGSSCTVS--ATLRQLESMIRLSEAR 764
Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSI 637
AKM V+ V EA R+++ ++
Sbjct: 765 AKMRYGSEVSVEDVVEAKRIISAAL 789
>UniRef50_Q54VI9 Cluster: MCM family protein; n=1; Dictyostelium
discoideum AX4|Rep: MCM family protein - Dictyostelium
discoideum AX4
Length = 867
Score = 236 bits (577), Expect = 2e-60
Identities = 115/242 (47%), Positives = 166/242 (68%)
Query: 302 LTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT 361
L+ E +++++ + S+ N ++ + TSL PSI G++ +KR +LL+L GGV +
Sbjct: 283 LSKEVSGPSLSEQDVTNIKNFSKYDNCFDLIATSLAPSICGHDNIKRSLLLLLLGGVERN 342
Query: 362 TIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEES 421
GT LRGDIN+ +VGDPSTAKSQLL+ + I P A+ T+G+ SS GLTAAV D E+
Sbjct: 343 LANGTHLRGDINLLMVGDPSTAKSQLLRFILNIAPLAINTTGRGSSGVGLTAAVTSDSET 402
Query: 422 FDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSI 481
+ +EAGA++LAD G+ CIDEFDKM P D+VAIHE MEQQT++++KAG+ A+LNAR S+
Sbjct: 403 GERRLEAGAMVLADRGIVCIDEFDKMSPDDRVAIHEVMEQQTVTISKAGIHASLNARCSV 462
Query: 482 LAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNK 541
+AAANPI G+Y+ N+ L ++SRFDL FI++D + D IA ++ +H K
Sbjct: 463 VAAANPIYGKYNPDLKAHTNIGLPDSLLSRFDLLFIVLDGINPDHDRMIAEHVLRMHRYK 522
Query: 542 EE 543
+E
Sbjct: 523 DE 524
Score = 42.3 bits (95), Expect = 0.049
Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 5/113 (4%)
Query: 526 VDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXX 584
+D + +K L E D V S + +YI +A++ FKP +T+EA + ++E Y
Sbjct: 556 LDTPVFQKYNKLLHGAENKSDIV-SIPFIQKYIFYAKTLFKPRLTDEAREYIIEKYTEMR 614
Query: 585 XXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
IT R LE+M+RL++ AK +VT A ++N+++
Sbjct: 615 SKQTPNSIP---ITTRSLETMIRLSQAHAKCRLDHNVTVDDTIVAIEIMNRAL 664
Score = 41.5 bits (93), Expect = 0.086
Identities = 18/53 (33%), Positives = 30/53 (56%)
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVP 234
+ D Q + IQE P G +PRS++++L + V++V+ GDR G +P
Sbjct: 208 YKDSQMVSIQEMPERAPAGQLPRSVDILLDNDLVDTVKPGDRVQVYGVYRAIP 260
>UniRef50_Q4QAP2 Cluster: Minchromosome maintenance (MCM) complex
subunit, putative; n=5; Trypanosomatidae|Rep:
Minchromosome maintenance (MCM) complex subunit,
putative - Leishmania major
Length = 801
Score = 235 bits (576), Expect = 3e-60
Identities = 141/357 (39%), Positives = 203/357 (56%), Gaps = 18/357 (5%)
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSM 241
+ D Q I++QE ++P G +PR L V++ V+ + G R G + V G
Sbjct: 229 YEDQQIIKLQELPEDVPTGELPRHLTVVVDRYLVDRISPGSRVQIVGVVSVQEKRGGFD- 287
Query: 242 PGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHD 301
+R R Q L+ +G+ + T C+V +V++ F ++ + +
Sbjct: 288 -SARGGGRGRAAAGLRAQY-----LRCVGL--MFRTTQDANCAVVSVNQNF-SSRVRSRS 338
Query: 302 LTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT 361
T ++ + K + K ++ L S+ P+I G + K+ ++ +LFGG K
Sbjct: 339 TMTWQPEEEASFKAFAK------QGGVFQKLSASIDPAIFGLEDQKKAIVCLLFGGTRKR 392
Query: 362 TIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEES 421
I LRGD+NV +GDPSTAKSQLLK V ++ P +YTSGK SSAAGLTA+V+ +
Sbjct: 393 -IGSNFLRGDMNVLFIGDPSTAKSQLLKFVEKVAPIGIYTSGKGSSAAGLTASVISNGNG 451
Query: 422 FDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSI 481
DFV+EAG+++LAD GV CIDEFDKM DQVAIHEAMEQQTIS+AKA + LN+RTS+
Sbjct: 452 -DFVLEAGSMVLADGGVVCIDEFDKMREQDQVAIHEAMEQQTISIAKANMTTMLNSRTSV 510
Query: 482 LAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
LAAANP G YD +S + + I+SRFDL F +ID + D +A ++ LH
Sbjct: 511 LAAANPTLGSYDPLRSNEDQMDFQSSILSRFDLIFKVIDPRNPETDQRLAHHVISLH 567
>UniRef50_A7ARB5 Cluster: ATP dependent DNA helicase, putative; n=1;
Babesia bovis|Rep: ATP dependent DNA helicase, putative
- Babesia bovis
Length = 765
Score = 235 bits (576), Expect = 3e-60
Identities = 130/340 (38%), Positives = 200/340 (58%), Gaps = 7/340 (2%)
Query: 300 HDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVA 359
H D K ++ + RD +LY L S+ P I+G+ +VK+ +LL L GGV
Sbjct: 329 HQKKVLDANKSSDSDLARRIEALRRDPDLYERLAYSIAPEIYGHEDVKKALLLQLIGGVT 388
Query: 360 KTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE 419
+ +G +RG I++ ++GDP AKSQLLK+V I+ R VYT+GK SS+ G+TAA+V+D
Sbjct: 389 REKKDGGIIRGSIHILLLGDPGVAKSQLLKKVCLISSRGVYTTGKGSSSTGMTAAIVKDP 448
Query: 420 ESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNART 479
++ + +E GAL+LAD G+CCIDEFDKMD D+ AI+E MEQQT+S+AKAG T+ AR+
Sbjct: 449 QTGETALEGGALVLADLGLCCIDEFDKMDDYDRSAIYEVMEQQTVSIAKAGHCTTMPARS 508
Query: 480 SILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC 539
++LAAANPI G YD K++ N+ L +++RFDL F+++D D +A +V+L
Sbjct: 509 AVLAAANPINGVYDVRKTVFHNMNLPAALLTRFDLQFLMLDRVDRGKDAQLAEHVVNLVK 568
Query: 540 NKEESYDCVYSRDD--LLR-YIAFARSFKPVITEEAGKLLVEYY----XXXXXXXXXXXX 592
+ Y+ D L+R YI A+ F+P +++ + + E+Y
Sbjct: 569 GVSQELTPKYAVVDKELMRTYIKMAQEFEPTMSQSIVEKVSEWYVNVRHQELDNETYNDE 628
Query: 593 XXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRL 632
T R + +++RL + +A++ S V + EA RL
Sbjct: 629 RFTYTTPRSMLAILRLCQAMARLRFSNTVEMSDFEEAVRL 668
Score = 39.5 bits (88), Expect = 0.35
Identities = 29/87 (33%), Positives = 43/87 (49%), Gaps = 3/87 (3%)
Query: 151 VQGTFYTIPTICRNPVCANRRRFMLDADK--SVFVDFQKIRIQETQAELPRGCIPRSLEV 208
+QG + T C + + N R L S F +Q++R+QE L G +P+SL+
Sbjct: 220 IQGPNFLPITDCVDCITRNNTRGTLKFHPRLSKFDKYQELRVQEPLYHLSEGELPKSLKC 279
Query: 209 ILRAEAVESVQAGDRYDFTGTLI-VVP 234
L E +SV+ GD G L+ VVP
Sbjct: 280 ELFGELTQSVRPGDSVLMYGILLPVVP 306
>UniRef50_Q7QSR9 Cluster: GLP_714_11088_8896; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_714_11088_8896 - Giardia lamblia
ATCC 50803
Length = 730
Score = 235 bits (574), Expect = 5e-60
Identities = 131/327 (40%), Positives = 192/327 (58%), Gaps = 9/327 (2%)
Query: 318 KVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIV 377
K + N+ + + + + P I G + KR + +LFGG K T E LRG+INV ++
Sbjct: 325 KFHAFKNQPNVISVIESLIAPQIEGMEDAKRAIACLLFGGTNKYTQELIRLRGNINVLLI 384
Query: 378 GDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNG 437
DP KS+LL + S + P +YTSGK++SA GLTA V+RD+ + +F +E GAL+LAD G
Sbjct: 385 SDPGLGKSELLLEASRLAPIGIYTSGKSTSAVGLTAGVMRDKATSEFFLEGGALVLADKG 444
Query: 438 VCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKS 497
+ CIDE DKM+ D+VA+HEAMEQ +IS++KAG+ TLNARTSILAAANP GR+D +
Sbjct: 445 IVCIDELDKMNETDRVALHEAMEQGSISISKAGISTTLNARTSILAAANPTLGRFDDFQK 504
Query: 498 LQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNK-------EESYDCVYS 550
+ S I++RFDL F+L D+ S D I KI + + + + +++
Sbjct: 505 AADQIDFSVTILTRFDLVFMLKDKQSPERDAMIVNKIARIAAGERPASVASHQEQNPMFT 564
Query: 551 RDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLA 609
+ L +YIA+A+ + P + + + ++L Y ITVRQLE+++RL+
Sbjct: 565 QSFLKKYIAYAQATCTPKLDQSSLEILKAAYIRYRADALKNSSAI-PITVRQLEALIRLS 623
Query: 610 EGVAKMHCSGHVTPAHVHEAYRLLNKS 636
E AKM S VT V A + KS
Sbjct: 624 ESFAKMRLSPVVTVEDVEYAIDIFQKS 650
>UniRef50_Q4Q8I2 Cluster: Minichromosome maintenance (MCM) complex
subunit, putative; n=5; Trypanosomatidae|Rep:
Minichromosome maintenance (MCM) complex subunit,
putative - Leishmania major
Length = 969
Score = 235 bits (574), Expect = 5e-60
Identities = 117/238 (49%), Positives = 162/238 (68%), Gaps = 2/238 (0%)
Query: 303 TTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTT 362
TTE ++ D E ++ E+S+ N+ L+ S+ PSIHG +++K G+LL + G V K
Sbjct: 469 TTELGMLRLPDDERQRIIELSKSPNIRKKLLQSIAPSIHGRDDIKLGLLLAMMGAVPKDI 528
Query: 363 --IEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEE 420
+ +RGDINV +VGDP AKSQ LK V + R V+T+G+ S+A GLTA+V +D
Sbjct: 529 GGDQSHRIRGDINVLMVGDPGCAKSQFLKFVEKTADRTVFTTGRGSTAVGLTASVHKDSV 588
Query: 421 SFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTS 480
+ DFV+E GAL++AD G C IDEFDKM D+ +IHEAMEQQTIS+A+ G+ TL+AR
Sbjct: 589 NGDFVLEGGALVIADRGCCLIDEFDKMSDQDRTSIHEAMEQQTISVARGGIVTTLSARCC 648
Query: 481 ILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
I+AAANP+GGRYD + S NV+L+ PI+SRFDL F++ DE + +D +A I D H
Sbjct: 649 IIAAANPMGGRYDPSTSFDANVSLTTPILSRFDLLFVVRDEVNVELDERLATFICDSH 706
Score = 60.5 bits (140), Expect = 2e-07
Identities = 46/206 (22%), Positives = 92/206 (44%), Gaps = 20/206 (9%)
Query: 40 YEKHAKELLKPELSTLEVSFDDVEK-YNQNLATTIIEEYYRIYPFLNRAILNYILSLAET 98
YE+ + + + ++S+D + + Y+ LA +++ + L A NY
Sbjct: 235 YEEKVNAMTRENDKSFQLSYDHLSRVYDSVLALWLVDAPDPMIELLEEAA-NYFTFKVYP 293
Query: 99 GMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF--- 155
+K +V D+P +R+ + L+R+ G ++R PV+P++ +
Sbjct: 294 QYRK--VHSHIFVRICDLPLCDPIRDFRQVHMNVLVRVEGVVIRRSPVYPQMDAVKYDCA 351
Query: 156 ---YTIPTICRN----------PVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202
Y I I + P C ++ F ++ + + + Q I +QE ++P G +
Sbjct: 352 RCSYIIGPIYQRGDKEQRVSMCPSCHSKGPFRVNMRLTEYRNHQTIVLQEPPGKVPPGRL 411
Query: 203 PRSLEVILRAEAVESVQAGDRYDFTG 228
PRSLEV+L + ++ + G+ D TG
Sbjct: 412 PRSLEVVLTNDLIDRAKPGEEVDVTG 437
Score = 35.1 bits (77), Expect = 7.5
Identities = 17/46 (36%), Positives = 28/46 (60%)
Query: 597 ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642
ITVR +ES++RL+E A++H +VT V A L + I+ ++
Sbjct: 821 ITVRHMESVIRLSEAHARVHLREYVTDEDVTAAVSLFLRCFIQTQK 866
>UniRef50_A5YS59 Cluster: MCM family protein; n=1; uncultured
haloarchaeon|Rep: MCM family protein - uncultured
haloarchaeon
Length = 647
Score = 235 bits (574), Expect = 5e-60
Identities = 132/350 (37%), Positives = 203/350 (58%), Gaps = 25/350 (7%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTT-LR 369
+TD + ++ E++ ++Y L S+ PSI+G K + L LF GV K +G + LR
Sbjct: 290 ITDSDETRIEELADSYDIYERLSQSIAPSIYGYENEKLALALQLFSGVTKHVDDGNSRLR 349
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEE---SFDFVI 426
GDI++ VGDP TAKSQ+++ V ++ PR V TSGK SSAAG+TAA VRD + S + +
Sbjct: 350 GDIHILFVGDPGTAKSQIIRYVKQLAPRGVLTSGKGSSAAGITAAAVRDSDFGGSDKWTL 409
Query: 427 EAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAAN 486
+AGAL+LAD GV C+DE DKM+ D+ A+ EA+EQQT+S+ KAG+ ATL +R S+LAAAN
Sbjct: 410 QAGALVLADKGVACVDELDKMESNDRAALLEALEQQTVSVNKAGINATLRSRCSLLAAAN 469
Query: 487 PIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIV----------- 535
P GR++ + + + L PP++SRFDL F++ D++ E VD I+ I+
Sbjct: 470 PSKGRFEEHVVISEQIDLEPPLISRFDLIFVVTDDADEEVDSEISSHILNTNKLGQQIAS 529
Query: 536 -------DLHCNKEESYDCVYSRDDLLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXX 587
D N+ + + D +Y+A AR P+++ EA L+ ++Y
Sbjct: 530 EPTESSTDNRNNEPTNGKEIIDADLFRKYVAHARKTNTPILSPEAESLIQDFYVQIRSDG 589
Query: 588 XXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
IT R+LES++RL+E A++ S + + A ++ S+
Sbjct: 590 SEDGRI--PITARKLESIIRLSEASARVRLSDTIKKSDAQRAINIVRMSL 637
>UniRef50_A7PSR8 Cluster: Chromosome chr8 scaffold_29, whole genome
shotgun sequence; n=3; Magnoliophyta|Rep: Chromosome
chr8 scaffold_29, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 741
Score = 233 bits (570), Expect = 1e-59
Identities = 145/419 (34%), Positives = 243/419 (57%), Gaps = 26/419 (6%)
Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSV 181
++ L +A I L+ + G +V+ V P +VQ TF + + +F + ++
Sbjct: 131 LKNLKSAYIDKLVSVRGTVVKASTVKPLVVQMTFACVKCQTNILRIFHDGKFSPPSHSTI 190
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSM 241
F DF+ + + + +G +PR++E L + V++ GD TG + + + + +
Sbjct: 191 F-DFKIMHLPF----ILKGRVPRTVECELTEDLVDACIPGDVVTVTGIIRQINNY--MDI 243
Query: 242 PGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHD 301
G +++ N+ Q L+A+ ++ + K+ +++ +Q + EL D
Sbjct: 244 GGGKSK--------NKNQGLFYLYLEAVSIK--NSKSQYISEDLQDSNADARATELL--D 291
Query: 302 LTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAK- 360
L + R D E+ + + + ++ S+ PSI+G+ VK G+ L LFGGV K
Sbjct: 292 LFSFSPR----DLEFIVKFSEEHGSDRFRQILQSICPSIYGHELVKAGITLALFGGVQKY 347
Query: 361 -TTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE 419
T +RGDI++ +VGDP KSQLL+ + I+PR +Y G A++ AGLT AVV+D
Sbjct: 348 STDKNKVPVRGDIHIIVVGDPGLGKSQLLQAAAAISPRGIYVCGNATTNAGLTVAVVKDP 407
Query: 420 ESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNART 479
+ D+ EAGA++LAD G+CCIDEFDKM Q ++ EAMEQQ +S+AKAG+ A+L+ART
Sbjct: 408 MTSDYAFEAGAMVLADRGLCCIDEFDKMSAEHQ-SLLEAMEQQCVSVAKAGLVASLSART 466
Query: 480 SILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
S+LAAANP+GG Y+RAK++ +N+ +S ++SRFDL FIL+D+ E++D ++ I+ ++
Sbjct: 467 SVLAAANPVGGHYNRAKTVNENLKMSAALLSRFDLVFILLDKPDELLDKRVSEHIMSVN 525
Score = 43.6 bits (98), Expect = 0.021
Identities = 26/85 (30%), Positives = 45/85 (52%), Gaps = 3/85 (3%)
Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612
L +YIA+AR+F P +++ A ++L ++Y IT RQLES+VRLAE
Sbjct: 572 LRKYIAYARTFVFPRMSKPAAEILQKFYLRLRDHSTSADGTP--ITARQLESLVRLAEAR 629
Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSI 637
A++ +T + ++ +S+
Sbjct: 630 ARLDLREEITAQDALDVVEIMKESL 654
>UniRef50_UPI00015B44D4 Cluster: PREDICTED: similar to MCM8
minichromosome maintenance deficient 8 (S. cerevisiae);
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to MCM8
minichromosome maintenance deficient 8 (S. cerevisiae) -
Nasonia vitripennis
Length = 777
Score = 232 bits (567), Expect = 3e-59
Identities = 127/342 (37%), Positives = 203/342 (59%), Gaps = 13/342 (3%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
++ K++ + ++ ++ + L+ SL P I+G+ +K +LL LFGG +K LR
Sbjct: 364 ELNTKDYKYIKDIHSSPDILSLLVNSLCPGIYGHEMIKMALLLSLFGGSSKHA----NLR 419
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
+I++ IVGDP KSQ+L+ + + P+ +Y SG +S+++GLT +VR++ DF +E G
Sbjct: 420 DNIHLLIVGDPGLGKSQMLQACARVAPKGIYVSGNSSTSSGLTVTLVREKGESDFALEPG 479
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489
AL+LAD G CCIDEFDKM P ++ EAMEQQ++S+AK+GV +L +RTSILAAANPIG
Sbjct: 480 ALVLADRGCCCIDEFDKM-PTQHQSLLEAMEQQSVSVAKSGVIWSLPSRTSILAAANPIG 538
Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEES 544
GRYDR+K+L N+ +S P++SRFDL F+L+D+ + +D ++ ++ +H EE+
Sbjct: 539 GRYDRSKALCNNLNMSQPLLSRFDLIFLLLDQPDKDLDNFLSEHVMMMHTGHVQTKSEEN 598
Query: 545 YDCVYSRDDLLRYIAFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLE 603
L +YI++AR + KP ++ + LL +YY RQLE
Sbjct: 599 SIQTMPSAVLRKYISYARQYVKPRLSSASATLLQKYYLDIRKKMINAVNLA--PCNRQLE 656
Query: 604 SMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDI 645
+++RL E AK+ T + LL +++ + I
Sbjct: 657 ALIRLTEARAKLDLREETTEQDALDVVELLQHTVLGMNNEKI 698
>UniRef50_A3M0C1 Cluster: DNA replication licensing factor, MCM2
component; n=8; Eukaryota|Rep: DNA replication licensing
factor, MCM2 component - Pichia stipitis (Yeast)
Length = 859
Score = 231 bits (564), Expect = 7e-59
Identities = 147/449 (32%), Positives = 239/449 (53%), Gaps = 60/449 (13%)
Query: 108 ECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPEL------------VQGTF 155
E +V V P +R+L + LI++ G + R V P+L V G F
Sbjct: 293 EIHVRIVGFPKHTNLRDLRENDLNQLIKVGGVVTRRTGVFPQLKYVKFDCLKCGVVLGPF 352
Query: 156 YTIP------TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVI 209
+ C N C ++ F ++++K+++ ++Q+I +QE+ +P G +PR EV
Sbjct: 353 IQDSNTEVRISFCTN--CQSKGPFRMNSEKTLYRNYQRITLQESPGTVPAGRLPRHREV- 409
Query: 210 LRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKAL 269
I++ D+ ++ PG E+T K +G + G
Sbjct: 410 ---------------------ILLSDLVDVAKPGEEIEVTGIYKNNYDGNLNAKNGFPV- 447
Query: 270 GVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLY 329
+ T A S++ + +E+ +++E +S+++ +
Sbjct: 448 ------FATIIEANSIRRKESSY-----------SENSLSSWSEEEESSFRRLSQEKGII 490
Query: 330 NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLK 389
+ +I+S+ PSI+G+ ++K + LFGGV K ++RGDINV ++GDP TAKSQ+LK
Sbjct: 491 DKIISSMAPSIYGHKDIKTAIACSLFGGVPKDVNGKHSIRGDINVLLLGDPGTAKSQILK 550
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
+ RAV+ +G+ +SA GLTA+V +D + ++ +E GAL+LAD G C IDEFDKM+
Sbjct: 551 YAEKTANRAVFATGQGASAVGLTASVRKDPITREWTLEGGALVLADKGTCLIDEFDKMND 610
Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509
D+ +IHEAMEQQ+IS++KAG+ TL AR +I+AAANP GGRY+ L QNV L+ PI+
Sbjct: 611 QDRTSIHEAMEQQSISVSKAGIVTTLQARCAIIAAANPNGGRYNSTLPLSQNVDLTEPIL 670
Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLH 538
SRFD+ ++ D + D +A ++D H
Sbjct: 671 SRFDILCVVRDLVNPESDERLASFVIDSH 699
Score = 39.5 bits (88), Expect = 0.35
Identities = 30/111 (27%), Positives = 54/111 (48%), Gaps = 4/111 (3%)
Query: 533 KIVDLHCNKEESYDCVYSRDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXX 591
KI L+ KE + S++ L++YI +AR +P + + + Y
Sbjct: 731 KISQLNKQKESEISPI-SQELLMKYINYARVKVQPKLHQMDMDKVARVYAELRKESISTG 789
Query: 592 XXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642
+ ITVR LES++R+AE AKM S V+ + ++ A ++ S + ++
Sbjct: 790 S--FPITVRHLESILRIAEAFAKMRLSDFVSQSDLNRAIKVSIDSFVGAQK 838
>UniRef50_Q7RJM3 Cluster: DNA replication licensing factor mcm7;
n=8; Plasmodium|Rep: DNA replication licensing factor
mcm7 - Plasmodium yoelii yoelii
Length = 850
Score = 230 bits (563), Expect = 1e-58
Identities = 135/351 (38%), Positives = 205/351 (58%), Gaps = 27/351 (7%)
Query: 313 DKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDI 372
DK ++V ++ NLY L ++ P I+G+ +VK+ +LL L GG K +G +RGDI
Sbjct: 400 DKIMEEVQKLKSSPNLYERLAYNIGPEIYGHEDVKKALLLQLIGGCTKKKKDGGLIRGDI 459
Query: 373 NVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALM 432
++ ++GDP AKSQL+K+V I R++YT+GK SS+ GLTAAV++D + + +E GAL+
Sbjct: 460 HILLMGDPGVAKSQLMKKVCLIASRSIYTTGKGSSSVGLTAAVLKDPNTGETTLEGGALV 519
Query: 433 LADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRY 492
LAD G+CCIDEFDKMD D+ AI+E MEQQT+S+AKAG + + AR+S+LAAANPI GRY
Sbjct: 520 LADKGICCIDEFDKMDEFDRSAIYEVMEQQTVSIAKAGHCSNMPARSSVLAAANPINGRY 579
Query: 493 DRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVD-LHC------------ 539
D KS+ N+ L +++RFDL F+L+D S D +A +++ L C
Sbjct: 580 DCKKSVMLNMNLPAALLTRFDLQFLLLDISDRDKDKRLAEHVLNILKCVDSTDDKKKKRK 639
Query: 540 -------NKEESYDCVYSRDD---LLRYIAFARSFKPVITEEAGKLLVEYY-XXXXXXXX 588
NK+++ D Y D L +I A+ +P I+ E + ++Y
Sbjct: 640 KKKTGLNNKDDNDDDGYEEIDKTVLRAFIQLAKRKQPTISPELIPKITQWYVSSRQLESQ 699
Query: 589 XXXXXXWRI---TVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKS 636
RI T R L +++R+++ +A++ S + EA RL +S
Sbjct: 700 QERYNDTRINYTTPRALLAILRISQALARVRDSDIIETPDFEEAIRLTEQS 750
Score = 55.2 bits (127), Expect = 7e-06
Identities = 36/106 (33%), Positives = 50/106 (47%), Gaps = 6/106 (5%)
Query: 142 RTHPVHPELVQGTFYTIPTICRNPVCAN----RRRFMLDADKSVFVDFQKIRIQETQAEL 197
R H + V G F+ C P C N R A S FV +Q+I++QE ++L
Sbjct: 269 RCHVFAYKAVDGPFFMPLFDC--PGCTNVHGIRGSLKFQAKLSKFVKYQEIKVQELASQL 326
Query: 198 PRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPG 243
P G IPRS+ I+ + SVQ G TG L+ V G ++ G
Sbjct: 327 PEGDIPRSMNCIIHGASTTSVQPGMHVTLTGVLMPVTKSGFQALKG 372
>UniRef50_Q5DVG0 Cluster: MCM/Rep protein; n=1; Sulfolobus
neozealandicus|Rep: MCM/Rep protein - Sulfolobus
neozealandicus
Length = 759
Score = 230 bits (563), Expect = 1e-58
Identities = 119/331 (35%), Positives = 196/331 (59%), Gaps = 1/331 (0%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
++++++ ++ E+++ +++ + +I S+ PSI+G+ K G+ L LFGGV +GT R
Sbjct: 348 EISEEDEQRIRELAKRQDIVDVIIKSIAPSIYGHEFEKEGIALALFGGVPSVRKDGTRRR 407
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
GDI+V I+GDP TAKSQLL+ V + PR+++ GK ++ GL+ VV D ++ ++ IE G
Sbjct: 408 GDIHVLIIGDPGTAKSQLLQFVKNLIPRSIFVDGKNATGVGLSGTVVIDPDTKEWRIEGG 467
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489
A+ LAD G IDEFDK+ ++ I+ AMEQQ + L KA L+ART+++A ANP
Sbjct: 468 AIALADGGFLLIDEFDKIPEEERSRINTAMEQQIVKLDKANQHFELDARTTVIAVANPRY 527
Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVY 549
RY +++ +N++ P I+SRFDL ++ID+ E D +A I + EE+ + V
Sbjct: 528 IRYIEDRTVAENISFKPDILSRFDLISVVIDKHDEEQDRKLAEHISNNELGTEEAGNSVI 587
Query: 550 SRDDLLRYIAFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRL 608
D L +Y+ +AR + KP T+EA L E++ IT RQ E+++R+
Sbjct: 588 DTDTLRKYVIYARKYIKPKFTKEALDTLKEFFVTIRNKTKDLTDFPLEITTRQYEALLRI 647
Query: 609 AEGVAKMHCSGHVTPAHVHEAYRLLNKSIIR 639
++ AKM S V V A + +++ + R
Sbjct: 648 SQAYAKMRLSNQVEQQDVERAIKFVSEMLRR 678
Score = 76.2 bits (179), Expect = 3e-12
Identities = 62/264 (23%), Positives = 124/264 (46%), Gaps = 38/264 (14%)
Query: 6 TYATQSQVKDEVGIRCQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDV--- 62
TY+ + V D+ + + +DF+ ++E Y + +E+ K + + ++++ +
Sbjct: 57 TYSNEDLV-DKATVDYSQALEDFILNYEEQGVKVYLRKKEEVEKRKAKSFYINWNHLYTW 115
Query: 63 -----EKYNQNLATTIIEEYYRIYPFLNRAILNYI------LSLAETGMKKDLQDKECYV 111
+Y NLA ++E+ + ++ + + L L+E G D D +V
Sbjct: 116 FEQHKNEYPLNLALELLEDPLELLKSISGWVYDLFARGKEPLQLSEYGKTVDKPD--FHV 173
Query: 112 SFVDVPTRHKVRELTTA--KIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRN----- 164
D+P + ++R++ T ++G L+ I G + P+L++G + + + C
Sbjct: 174 RITDIPRKLEMRKIGTQFIQVGKLVEIKGVVFSKTLPKPKLIKGHYRHLRSDCLGEFDFP 233
Query: 165 --------------PVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVIL 210
P+C +L +++SV+ +QK+ IQET ELP G +PR LE+ L
Sbjct: 234 NTEIEELEITPKHCPLCGKTGEIVLISERSVYTSWQKVVIQETTEELPPGEVPRQLELEL 293
Query: 211 RAEAVESVQAGDRYDFTGTLIVVP 234
+ V++V+ GD+ D G L+ P
Sbjct: 294 LDDLVDTVKIGDKIDVVGVLMAKP 317
>UniRef50_Q6NRM6 Cluster: DNA replication licensing factor MCM9;
n=1; Xenopus laevis|Rep: DNA replication licensing
factor MCM9 - Xenopus laevis (African clawed frog)
Length = 1143
Score = 230 bits (563), Expect = 1e-58
Identities = 131/320 (40%), Positives = 196/320 (61%), Gaps = 10/320 (3%)
Query: 296 ELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLF 355
E P + E++RK+ D W K + N ++ SL P + G VK V ++L
Sbjct: 274 EQPCGVVINEEVRKEYEDF-WVKYRNNPLEGR--NEILASLCPQVFGMFVVKLAVAMVLA 330
Query: 356 GGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAV 415
GGV + GT +RG+ ++ +VGDP T KSQ LK ++ITPR+V T+G S++AGLT
Sbjct: 331 GGVQRIDSAGTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTAGIGSTSAGLTVTA 390
Query: 416 VRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATL 475
V+D S ++ +EAGAL+LAD G+CCIDEF+ + D+ +IHEAMEQQTIS+AKAG+ L
Sbjct: 391 VKD--SGEWNLEAGALVLADGGLCCIDEFNSIKEHDRTSIHEAMEQQTISVAKAGLVCKL 448
Query: 476 NARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIV 535
N RT+ILAA NP G+YD +S+ NVAL+ P++SRFDL +L+D +E D I+ I+
Sbjct: 449 NTRTTILAATNP-KGQYDPDESISVNVALASPLLSRFDLVLVLLDTKNEDWDRIISSFIL 507
Query: 536 DLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXW 595
+ +S D ++S + + Y ++ +P ++++A +LV YY
Sbjct: 508 ESKGCPRKS-DKLWSMEKMKTYFCLIKNLQPKMSQDANVILVRYYQLQRQSSCRNAA--- 563
Query: 596 RITVRQLESMVRLAEGVAKM 615
R T+R LES++RLAE A++
Sbjct: 564 RTTIRLLESLIRLAEAHARI 583
Score = 43.6 bits (98), Expect = 0.021
Identities = 26/76 (34%), Positives = 39/76 (51%), Gaps = 3/76 (3%)
Query: 159 PTICRNPVCANRRRFMLDADKSVFV---DFQKIRIQETQAELPRGCIPRSLEVILRAEAV 215
P C N N +F +D S D+Q+I+IQE L G IPRS+ V+L + V
Sbjct: 171 PIACSNEEGCNSTKFTCLSDSSSPASCRDYQEIKIQEQVQRLSVGSIPRSMIVVLEDDLV 230
Query: 216 ESVQAGDRYDFTGTLI 231
+S ++GD G ++
Sbjct: 231 DSCKSGDDITVYGVVM 246
>UniRef50_Q8SS42 Cluster: DNA REPLICATION LICENSING FACTOR MCM2;
n=1; Encephalitozoon cuniculi|Rep: DNA REPLICATION
LICENSING FACTOR MCM2 - Encephalitozoon cuniculi
Length = 780
Score = 230 bits (562), Expect = 1e-58
Identities = 133/344 (38%), Positives = 205/344 (59%), Gaps = 19/344 (5%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
+MTD + ++ +M R + +I S+ PS++G+ EVKR + L + GGVA+ + +R
Sbjct: 357 EMTDDDVREIKKMGRHPEIKRIVINSIAPSVYGHAEVKRAIALAMLGGVARESTSHR-IR 415
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
GDINV ++GDP AKSQ L+ V + RAV +G+ +S+ GLTA+V +D ++ +E G
Sbjct: 416 GDINVLLLGDPGMAKSQFLRYVESTSHRAVLATGQGASSVGLTASVRKDPVVKEWTLEGG 475
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489
AL+LAD G+C IDEFDKM+ D+ +IHEAMEQQ+IS++KAG+ ATL+AR S++AAANP+
Sbjct: 476 ALVLADKGICLIDEFDKMNEHDRTSIHEAMEQQSISISKAGIVATLHARCSVIAAANPMR 535
Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYD--- 546
GRY+ + + QNV LS PI+SRFD+ ++ D D A+ +++ H EE D
Sbjct: 536 GRYNGSLTFAQNVNLSDPIISRFDILCVVKDAIDAGEDEKTAKFVIESHEGGEEKPDGFD 595
Query: 547 ---CVYSRDDLLRYIAFAR-----SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRIT 598
+ + L +YI +AR +F V E+ L +E +T
Sbjct: 596 PKRMMMGHELLRKYILYARTNVVPAFNDVDMEKISSLYLE-------LRKESLPSGLPVT 648
Query: 599 VRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642
VR +ES+VR++E AKM S V+ + EA ++ S + ++
Sbjct: 649 VRHVESIVRISEAFAKMRLSRVVSVEDIDEAISVVLDSFMGAQK 692
Score = 80.6 bits (190), Expect = 2e-13
Identities = 59/222 (26%), Positives = 104/222 (46%), Gaps = 22/222 (9%)
Query: 23 KLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYP 82
K+ + F+ F E KY K +++ L ++EVS+ D+E+ + +L + +
Sbjct: 106 KVVRKFIRFFNEFGNKKYAKRIRQMCTENLESIEVSYLDIEEESIDLLRLLNQHAEMTIE 165
Query: 83 FLNRAILNYI-LSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIV 141
++RA+ + + + M K + + VD+P VR L +G L+R+SG +
Sbjct: 166 VMDRALSDVVRMHFPNYHMIKP----KVHSRVVDLPVCDSVRSLRNRHLGKLVRVSGVVT 221
Query: 142 RTHPVHP------------ELVQGTFYTI---PTICRNPVCANRRRFMLDADKSVFVDFQ 186
R V P V G F PT C C ++ F ++ ++V+ DFQ
Sbjct: 222 RRSGVFPLYSIVKFSCLKCRSVFGPFVASSFKPTHCFE--CQSKGPFTVNTSETVYKDFQ 279
Query: 187 KIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
K+ IQE +P G +PRS EV+L + ++ + G+ + TG
Sbjct: 280 KLTIQEIPGSVPPGSLPRSKEVLLFYDLIDCAKPGEEVEVTG 321
>UniRef50_Q6C0T3 Cluster: Similar to sp|P30666 Schizosaccharomyces
pombe DNA replication licensing factor mcm3; n=1;
Yarrowia lipolytica|Rep: Similar to sp|P30666
Schizosaccharomyces pombe DNA replication licensing
factor mcm3 - Yarrowia lipolytica (Candida lipolytica)
Length = 806
Score = 229 bits (560), Expect = 2e-58
Identities = 113/228 (49%), Positives = 159/228 (69%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRG 370
++D+E ++ +S+ + ++ L SL PSI G +K+ VLLML GG K GT +RG
Sbjct: 272 VSDEEVRQINLISKRDDAFDILSRSLAPSIFGFEYIKQAVLLMLLGGAEKNLENGTHIRG 331
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGA 430
DIN+ +VGDPSTAKSQ+L+ V A+ T+G+ SS GLTAAV D ++ + +EAGA
Sbjct: 332 DINILMVGDPSTAKSQMLRFVLNSANLAIATTGRGSSGVGLTAAVTMDTDTGERRLEAGA 391
Query: 431 LMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGG 490
++LAD GV CIDEFDKM D+VAIHE MEQQT+++AKAG+ TLNAR S++AAANP+ G
Sbjct: 392 MVLADRGVVCIDEFDKMSDTDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFG 451
Query: 491 RYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
+YD K +N+AL ++SRFDL FI+ DE+++ D IA ++ +H
Sbjct: 452 QYDVTKPPHKNIALPDSLLSRFDLLFIVTDETNDEKDRRIADHVIKMH 499
Score = 40.7 bits (91), Expect = 0.15
Identities = 18/47 (38%), Positives = 27/47 (57%)
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
++D Q I IQE + P G +P SLE++L + + V+ GDR G
Sbjct: 190 YMDHQTISIQEMPEKAPAGQLPTSLEIVLDDDLADKVKPGDRIQIIG 236
>UniRef50_UPI0000E48FA2 Cluster: PREDICTED: similar to
mini-chromosome maintenance deficient 9; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
mini-chromosome maintenance deficient 9 -
Strongylocentrotus purpuratus
Length = 1217
Score = 228 bits (557), Expect = 5e-58
Identities = 130/326 (39%), Positives = 198/326 (60%), Gaps = 18/326 (5%)
Query: 304 TEDMRKQMTDKEWDKV-YEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTT 362
TE+MR++ ++ WD + RN+ ++ SL P ++G VK V ++L GGVA+
Sbjct: 290 TEEMRQEF-EEFWDNHRFNPLSGRNI---ILASLCPQVYGLYVVKLAVGMVLAGGVARRD 345
Query: 363 IEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESF 422
GT RG+ ++ +VGDP T KSQ LK +++ PR+V T+G S++AGLT + VRD S
Sbjct: 346 ATGTRTRGESHLLLVGDPGTGKSQFLKYAAKVVPRSVLTTGIGSTSAGLTVSAVRD--SG 403
Query: 423 DFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSIL 482
++ +EAGAL+LAD G+CCIDEF+ + D+ +IHEAMEQQTIS+AKAG+ LN RT+IL
Sbjct: 404 EWTLEAGALVLADGGLCCIDEFNSIREHDRGSIHEAMEQQTISVAKAGLVCKLNTRTTIL 463
Query: 483 AAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKE 542
AA NP G+YD +S+ N+AL+ P++SRFD+ +L+D +E D ++ I++
Sbjct: 464 AATNP-KGKYDPGESISVNIALASPLLSRFDIVLVLLDSQNEDWDRVVSSFILEGKAPAP 522
Query: 543 ES-------YDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXW 595
E ++S + + Y++ ++ PV+T +A +L YY
Sbjct: 523 EGEKGDGAPASDLWSIEKMQTYLSIIKTIDPVLTPQANIVLSRYYQAQRQADMRNAA--- 579
Query: 596 RITVRQLESMVRLAEGVAKMHCSGHV 621
R T+R LESMVRLA+ A++ C V
Sbjct: 580 RTTIRLLESMVRLAQAHARLMCQTEV 605
Score = 44.8 bits (101), Expect = 0.009
Identities = 20/48 (41%), Positives = 33/48 (68%)
Query: 184 DFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLI 231
D+Q+++IQE +L G IPRS+ V+L + V++ +AGD TGT++
Sbjct: 207 DYQELKIQEQVHKLTMGTIPRSMWVVLEDDLVDTCKAGDDITVTGTVM 254
>UniRef50_A3ACA9 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 714
Score = 227 bits (556), Expect = 7e-58
Identities = 142/347 (40%), Positives = 194/347 (55%), Gaps = 47/347 (13%)
Query: 321 EMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDP 380
E ++ + Y + + + PSI+G+++VK+ + +LFGG K
Sbjct: 319 EFAQRPDAYVKICSMIGPSIYGHSDVKKAIACLLFGGSKK-------------------- 358
Query: 381 STAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCC 440
LK V + P AVYTSGK SSAAGLTA+V+RD S +F +E GA++LAD GV C
Sbjct: 359 ------FLKFVEKTAPIAVYTSGKGSSAAGLTASVIRDGSSREFYLEGGAMVLADGGVVC 412
Query: 441 IDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQ 500
IDEFDKM P D+VAIHEAMEQQTIS+AKAG+ LN+RTS+LAAANPI GRYD K+ Q
Sbjct: 413 IDEFDKMRPEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIAGRYDDLKTAQD 472
Query: 501 NVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCN----KEESYDCVYSRDDLLR 556
N+ L I+SRFDL FI+ D D IA I+ +H + ++ D + L R
Sbjct: 473 NIDLQTTILSRFDLIFIVKDVRMYDQDKRIASHIIKVHASGAAASSKNTDASEGENWLKR 532
Query: 557 YIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXX----------------XXXXXXWRITV 599
YI + R + KP ++E+A ++L Y ITV
Sbjct: 533 YIEYCRVTCKPRLSEKAAEMLQNKYVEIRQARAKDFSLSLTKMRQQAHETGRAAAIPITV 592
Query: 600 RQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIH 646
RQLE+++RL+E +AKM + TP HV EA+RL N S + + I+
Sbjct: 593 RQLEAIIRLSESLAKMRLTSVATPEHVEEAFRLFNVSTVDAARSGIN 639
Score = 37.9 bits (84), Expect = 1.1
Identities = 16/51 (31%), Positives = 30/51 (58%)
Query: 178 DKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
DKS +VD Q +++QE ++P G +PR++ + + V+++ G R G
Sbjct: 218 DKSKYVDLQTLKLQENPEDVPTGELPRNMLLSVDRHLVQTIVPGTRLTVIG 268
>UniRef50_A4RT02 Cluster: Replication origin activator MCM3,
probable; n=2; Ostreococcus|Rep: Replication origin
activator MCM3, probable - Ostreococcus lucimarinus
CCE9901
Length = 707
Score = 227 bits (555), Expect = 9e-58
Identities = 111/225 (49%), Positives = 158/225 (70%)
Query: 314 KEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDIN 373
++ ++ + + R L L SL PSI G+N +K+ ++L+L GG K GT +RGDIN
Sbjct: 266 EDMTRMANIVQPRQLLELLGRSLAPSICGHNHIKQALVLLLLGGNEKNLPNGTHIRGDIN 325
Query: 374 VCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALML 433
+VGDPS AKSQLL+ V + P A+ T+G+ SS GLTAA+ D E+ + +EAGA++L
Sbjct: 326 CLLVGDPSVAKSQLLRCVMGVAPFAISTTGRGSSGVGLTAAITSDMETGERRLEAGAMVL 385
Query: 434 ADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYD 493
AD GV CIDEFDKM+ D+VAIHE MEQQT++++KAG++A+LNAR S++AAANP+ G YD
Sbjct: 386 ADRGVVCIDEFDKMNDIDRVAIHEVMEQQTVTISKAGIQASLNARCSVVAAANPLYGTYD 445
Query: 494 RAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
A+SL +N+ L ++SRFDL F++ D S VD I+ ++ LH
Sbjct: 446 HAQSLSRNINLPDSLLSRFDLLFVIHDISDATVDRTISSHVLQLH 490
Score = 50.4 bits (115), Expect = 2e-04
Identities = 24/60 (40%), Positives = 37/60 (61%)
Query: 175 LDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVP 234
++ +S++VD Q+I IQE + P G +PRS++VIL + V+ + GDR G VVP
Sbjct: 172 IEYGESLYVDHQRICIQEMPEKAPAGQLPRSVDVILEEDLVDCCKPGDRVSIIGIYKVVP 231
Score = 40.7 bits (91), Expect = 0.15
Identities = 31/97 (31%), Positives = 42/97 (43%), Gaps = 4/97 (4%)
Query: 550 SRDDLLRYIAFA--RSFKPVITEEAGKLLVEYYXX--XXXXXXXXXXXXWRITVRQLESM 605
++ DL +Y+ F R ++ +T EA + E Y IT R LE+M
Sbjct: 530 TKSDLQKYLRFMKERPWEQKLTNEAEVCIAEQYAAWRLAKAEKTRTSSSIPITARTLETM 589
Query: 606 VRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642
+RLA AK+ S V EA RLL I EQ
Sbjct: 590 IRLASAHAKLRMSRKVERIDALEAIRLLKYGIEANEQ 626
>UniRef50_Q8SQL8 Cluster: DNA REPLICATION LICENSING FACTOR OF THE
MCM FAMILY MCM7; n=1; Encephalitozoon cuniculi|Rep: DNA
REPLICATION LICENSING FACTOR OF THE MCM FAMILY MCM7 -
Encephalitozoon cuniculi
Length = 694
Score = 227 bits (554), Expect = 1e-57
Identities = 125/309 (40%), Positives = 183/309 (59%), Gaps = 10/309 (3%)
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391
++ S+ P I G ++K+ +LLML G + +G +RGDINV +VGDP AKSQLLK
Sbjct: 323 MVRSIAPEIFGMEDIKKILLLMLIGAPGRVREDGMKIRGDINVLLVGDPGIAKSQLLKTC 382
Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451
+I R VYT+GK SS GLTA+V +D + + V+E GAL+LAD G+CCIDE DKM+ D
Sbjct: 383 VKIGRRGVYTTGKGSSGVGLTASVSKDPITGEMVLEGGALVLADGGICCIDELDKMNEVD 442
Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511
+V+IHE MEQQ++S++KAG+ +LNAR +L AANP+ G+YD +S++ N+ L ++SR
Sbjct: 443 RVSIHEVMEQQSVSISKAGINTSLNARCCVLGAANPVKGKYDTRQSIEHNIGLPCALLSR 502
Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEE 571
FD+ IL DE + D ++A I +H + EE Y + L+ I A+ PV+
Sbjct: 503 FDVVAILRDEPNLEKDESLANHITSIHLH-EEPESIPYDKIRLI--IDEAKRINPVLPSH 559
Query: 572 AGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYR 631
L + Y +T R L S++RL+ ++ S V V+EA R
Sbjct: 560 LSGKLTDAYVKARKESPY-------VTPRYLLSLIRLSLAHCRLRLSTDVNEDDVNEALR 612
Query: 632 LLNKSIIRV 640
L+ + I V
Sbjct: 613 LMEVTRIPV 621
Score = 47.6 bits (108), Expect = 0.001
Identities = 45/179 (25%), Positives = 74/179 (41%), Gaps = 24/179 (13%)
Query: 120 HKVRELTTAKIGTLIRISGQIVRTHPVHPEL-----------------VQGTFYTIPTIC 162
+ VR L + IG+L+R+SG + + V P + V G + + C
Sbjct: 145 YSVRGLKSMHIGSLVRVSGVVTKVSQVKPSIRVATYVCEGCGAETYQEVDGDVFDLLEEC 204
Query: 163 RNPVCANRR---RFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQ 219
+ C R +L S F+ Q + +QE ++PRGCIPR+L + E +
Sbjct: 205 GSEKCRIRNVRGTLVLVTRGSKFIKHQTVYMQELTGDIPRGCIPRTLVAECYSSMAEKCR 264
Query: 220 AGDRYDFTGTLIVVPDVGALSM-PGSRAEI---TTRTKLANEGQMEGIKGLKALGVREL 274
GD G + P G + G A+I T + G +G + +KA V ++
Sbjct: 265 PGDVVVVGGVFMPKPYHGIKKLKAGLLADIYLHATNIEKIGAGAPKGNEEVKAYPVEQM 323
>UniRef50_Q9NXL9 Cluster: DNA replication licensing factor MCM9;
n=30; Eukaryota|Rep: DNA replication licensing factor
MCM9 - Homo sapiens (Human)
Length = 1143
Score = 226 bits (553), Expect = 2e-57
Identities = 128/318 (40%), Positives = 195/318 (61%), Gaps = 10/318 (3%)
Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364
E+++K+ D W+ Y S N ++ SL P + G VK V ++L GG+ +T
Sbjct: 282 EEVQKEFEDF-WE--YYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAT 338
Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDF 424
GT +RG+ ++ +VGDP T KSQ LK ++ITPR+V T+G S++AGLT V+D S ++
Sbjct: 339 GTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGLTVTAVKD--SGEW 396
Query: 425 VIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAA 484
+EAGAL+LAD G+CCIDEF+ + D+ +IHEAMEQQTIS+AKAG+ LN RT+ILAA
Sbjct: 397 NLEAGALVLADAGLCCIDEFNSLKEHDRTSIHEAMEQQTISVAKAGLVCKLNTRTTILAA 456
Query: 485 ANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544
NP G+YD +S+ N+AL P++SRFDL +L+D +E D I+ I++ +S
Sbjct: 457 TNP-KGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFILENKGYPSKS 515
Query: 545 YDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLES 604
+ ++S + + Y R+ +P +++ ++L+ YY R T+R LES
Sbjct: 516 -EKLWSMEKMKTYFCLIRNLQPTLSDVGNQVLLRYYQMQRQSDCRNAA---RTTIRLLES 571
Query: 605 MVRLAEGVAKMHCSGHVT 622
++RLAE A++ VT
Sbjct: 572 LIRLAEAHARLMFRDTVT 589
Score = 41.9 bits (94), Expect = 0.065
Identities = 20/48 (41%), Positives = 31/48 (64%)
Query: 184 DFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLI 231
D+Q+I+IQE L G IPRS++VIL + V+S ++GD G ++
Sbjct: 198 DYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVM 245
>UniRef50_A0DH93 Cluster: Chromosome undetermined scaffold_50, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_50,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 810
Score = 226 bits (552), Expect = 2e-57
Identities = 114/241 (47%), Positives = 162/241 (67%), Gaps = 1/241 (0%)
Query: 319 VYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVG 378
+ E+++ NL + S+ PSI G+ VK+ +LL L GG K GT LRGDINV ++G
Sbjct: 300 IKEIAKKPNLLEYMSKSIAPSIFGHGIVKQSILLQLLGGTEKNLETGTHLRGDINVLLIG 359
Query: 379 DPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGV 438
DPSTAKSQLL+ V P V T+G+ +S+ GLTAAV RD E+ + +EAGA++LAD GV
Sbjct: 360 DPSTAKSQLLRYVMGTAPLVVTTTGRGTSSVGLTAAVKRDNETGENTLEAGAMVLADGGV 419
Query: 439 CCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSL 498
IDEFDKM+ D+VAIHE MEQQT+++AKAG+ +LNAR S+LAAANP+ G Y +
Sbjct: 420 ILIDEFDKMNEIDRVAIHEVMEQQTVTIAKAGIHCSLNARCSVLAAANPLYGEYQLDMAP 479
Query: 499 QQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYI 558
+N+ L ++SRFDL FI++DE + +D +A ++ H K + YD + D+++ +
Sbjct: 480 TKNIGLPDSLLSRFDLLFIILDEKKKDIDRKVAERVTKNHRYKGQ-YDDEENIGDIIQPM 538
Query: 559 A 559
A
Sbjct: 539 A 539
Score = 48.4 bits (110), Expect = 8e-04
Identities = 22/52 (42%), Positives = 31/52 (59%)
Query: 184 DFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPD 235
D Q + +QE P G +PRSLEVIL + V+ V+ GDR + TG +P+
Sbjct: 212 DMQTLVVQELPERTPTGMLPRSLEVILDQDLVDRVKPGDRVEITGVYKCIPN 263
>UniRef50_Q9UJA3 Cluster: DNA replication licensing factor MCM8;
n=35; Deuterostomia|Rep: DNA replication licensing
factor MCM8 - Homo sapiens (Human)
Length = 840
Score = 225 bits (550), Expect = 4e-57
Identities = 142/395 (35%), Positives = 214/395 (54%), Gaps = 39/395 (9%)
Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212
Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L
Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317
Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVR 272
+ V+S +PG IT K++N + G R
Sbjct: 318 DLVDSC----------------------VPGDTVTITGIVKVSNAEE----------GSR 345
Query: 273 ELHYKTAFLA-CSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331
+ K FL ++S G + D M + + K+ + E+ + NL+
Sbjct: 346 NKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKL 405
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLK 389
++ SL P I G+ VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+
Sbjct: 406 IVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQ 465
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
+ PR VY G ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM
Sbjct: 466 AACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN 525
Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509
Q A+ EAMEQQ+ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++
Sbjct: 526 QHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALL 584
Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544
SRFDL FIL+D +E D+ ++ ++ + K+ +
Sbjct: 585 SRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 619
Score = 39.1 bits (87), Expect = 0.46
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612
L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E
Sbjct: 666 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 723
Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638
A++ T + ++ S++
Sbjct: 724 ARLELREEATKEDAEDIVEIMKYSML 749
>UniRef50_Q00Y49 Cluster: DNA replication licensing factor, MCM5
component; n=4; Ostreococcus|Rep: DNA replication
licensing factor, MCM5 component - Ostreococcus tauri
Length = 1327
Score = 224 bits (548), Expect = 6e-57
Identities = 112/241 (46%), Positives = 161/241 (66%), Gaps = 5/241 (2%)
Query: 320 YEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEG---TTLRGDINVCI 376
+ ++ L+ SL PSI G++ VK G+LL LFGGV K+ + G RG ++ +
Sbjct: 410 FSQQSGEDIVRTLVHSLCPSIFGHDIVKLGLLLCLFGGVRKS-VSGCGKVPTRGSLHCLV 468
Query: 377 VGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADN 436
VGDP KSQ+LK VS + PR++Y G+ SAAGLTAAVVRD + EAGA++LAD
Sbjct: 469 VGDPGLGKSQMLKAVSNLAPRSIYVCGRTVSAAGLTAAVVRDPGTGAQTFEAGAIVLADR 528
Query: 437 GVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAK 496
GVCC+DEFDKM P + ++ EAMEQQ++S+ KAG+ ATL ARTSI+AAANP+ G Y+RAK
Sbjct: 529 GVCCVDEFDKM-PNEHQSLLEAMEQQSVSVCKAGLNATLPARTSIIAAANPVQGHYNRAK 587
Query: 497 SLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLR 556
++ +N+ +S P++SRFDL FIL+D + E++D ++ ++ H + +R +L
Sbjct: 588 TVNENLKMSAPLLSRFDLIFILLDMADEILDEHLSEHVIAQHSGRHNQARRAQARQNLHA 647
Query: 557 Y 557
Y
Sbjct: 648 Y 648
Score = 45.2 bits (102), Expect = 0.007
Identities = 26/92 (28%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Query: 548 VYSRDDLLRYIAFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMV 606
+ S D + +YI++A ++ P +T EA ++L +Y +T RQLES+V
Sbjct: 694 ILSHDIMRKYISYAHAYCHPRLTPEAAEVLQTFYLELRSRAPADGTP---VTARQLESLV 750
Query: 607 RLAEGVAKMHCSGHVTPAHVHEAYRLLNKSII 638
RL+E A++ VT +A ++ S++
Sbjct: 751 RLSEARARLELRTEVTANDAKDAVEIIKASLV 782
>UniRef50_UPI0000DB74DE Cluster: PREDICTED: similar to
minichromosome maintenance protein 8 isoform 1; n=1;
Apis mellifera|Rep: PREDICTED: similar to minichromosome
maintenance protein 8 isoform 1 - Apis mellifera
Length = 587
Score = 223 bits (546), Expect = 1e-56
Identities = 133/356 (37%), Positives = 207/356 (58%), Gaps = 39/356 (10%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
+M+ K++ + E+ N++ L+ SL PSI+G+ VK G++L LFGG +E + LR
Sbjct: 161 EMSIKDYLAIKEVYNTPNIFPLLVHSLCPSIYGHEIVKAGLILSLFGG----NVEHSELR 216
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
+I++ IVGDP KSQ+L+ + I + VY G +S+++GLT + ++ +S +F +E G
Sbjct: 217 ENIHILIVGDPGLGKSQMLQACARIAAKGVYVCGNSSTSSGLTITLAKENKSNNFNLEPG 276
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489
AL+L D G CCIDEFDKM V + EAMEQQ++S+AK+G+ +L RTSILAAANPIG
Sbjct: 277 ALVLTDRGCCCIDEFDKMCKQHAVLL-EAMEQQSVSIAKSGIICSLPTRTSILAAANPIG 335
Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCN-------KE 542
GR++R K++ QN+ +S P++SRFDL F+L+DE ++ +D + + ++ +H + +
Sbjct: 336 GRFNRNKTVIQNLKMSAPLLSRFDLIFLLLDEPNKHIDDLLCKHVMSIHTDINTIDKTQS 395
Query: 543 ESYDCVYSRD-------DLLR-----------------YIAFARSF-KPVITEEAGKLLV 577
+Y C+ + D D LR YIA+AR + KP +T+EA +L
Sbjct: 396 NTYQCINAPDTTKLSLRDKLRLSVDENPNIIPQSILRKYIAYARQYVKPKLTKEAAIILQ 455
Query: 578 EYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
YY + RQLE+M+RL E AK+ T A + +L
Sbjct: 456 NYYLKLRNKNNKFNGLS--VCNRQLEAMIRLTEARAKLELRTEATEADALDVIEIL 509
Score = 36.3 bits (80), Expect = 3.2
Identities = 24/79 (30%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 156 YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQE--TQAELPRGCIPRSLEVILRAE 213
+TIP C N ++ R +LD+ + FQ I+IQE + +G +PR +++ L +
Sbjct: 50 FTIPKKC-NLCGVSKFRVILDSPLIKSIPFQTIKIQEISNNDQNSKGNMPRMVDIELMDD 108
Query: 214 AVESVQAGDRYDFTGTLIV 232
V + GD TG + V
Sbjct: 109 LVNTCMPGDDITLTGIIKV 127
>UniRef50_Q7R0J9 Cluster: GLP_154_53758_56232; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_154_53758_56232 - Giardia lamblia
ATCC 50803
Length = 824
Score = 223 bits (546), Expect = 1e-56
Identities = 175/565 (30%), Positives = 288/565 (50%), Gaps = 57/565 (10%)
Query: 109 CY-VSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVC 167
CY V+F + ++ +R L +LI +SG + PE+V+ F T+C++
Sbjct: 172 CYPVNFPEDDSQ-SLRTLGPMHADSLISVSGMVSNISSRVPEMVEACFQC--TVCKDVKK 228
Query: 168 ANRRRFML---------DADKSV--------FVDFQKIRIQETQAELPRGCIPRSLEVIL 210
A+ +R + D+ +S+ F+D + I+IQE +L G P S +
Sbjct: 229 ASVKRGKIISPIQCTNCDSLQSIEIVHNMCTFIDKRVIKIQEAPDQLTSGTPPISCSFVA 288
Query: 211 RAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALG 270
+ ++ GDR +VV VG + +R + +++ + + L ++
Sbjct: 289 YDLDLSGIRPGDR-------VVV--VGIYRLRQTRPK---QSQAVCNAALRPVIELLSIF 336
Query: 271 VRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM-SRDRNLY 329
+ + ++L+ + + + + + + +T D + E S +
Sbjct: 337 ISDSAATDSYLSAKKDSDVTDYERLKSLDPNTSYAEYYNHVTRLFPDMIPETDSGSDKRF 396
Query: 330 NNLITSLFPSIHGN--NEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQL 387
LI S+ PSI G +++K G+LL FGGV K + RG I+V +VGDP AKS+L
Sbjct: 397 LKLINSIAPSIFGPAYSDIKTGLLLQCFGGVQKDSY-----RGQIHVLLVGDPGLAKSKL 451
Query: 388 LKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKM 447
L+ V++I+PR+VYTSGK SS AGLTA V R E+ +F ++ GAL+L+D G+CC+DEFDK
Sbjct: 452 LQYVAKISPRSVYTSGKGSSQAGLTATVSRHPETHEFYLDPGALLLSDGGICCLDEFDKS 511
Query: 448 DPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPP 507
+ ++HE ME +S+AKAG+ ATL+A+TSILAAANPI Y+ +++ QN+ L P
Sbjct: 512 SEDVRSSLHEVMEHGQLSIAKAGILATLSAKTSILAAANPIDSCYNPKRTVVQNLNLPPS 571
Query: 508 IMSRFDLFFILIDESSEM-VDYAIARKIVDL--------HCNKEESYDCVYSRDD----- 553
++SRFDL ++L+D + D A+A +V + H S + + D
Sbjct: 572 LLSRFDLIYLLLDNRHDTEADRALASWLVSMYISSGQAEHSGHLSSKNTAAATPDAWDPQ 631
Query: 554 -LLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612
L +YI FA+ PV+++ A L+ Y T RQL S++RLAE
Sbjct: 632 VLRQYIYFAQKLSPVLSKSAQDALLLSYNQLRSGSYSASGRI-TATPRQLMSLIRLAEAR 690
Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSI 637
A++ S VT + E RL+ +++
Sbjct: 691 ARIRFSNFVTANDILEVSRLMTRAM 715
>UniRef50_Q4UHR0 Cluster: DNA replication licensing factor (MCM5
homologue), putative; n=2; Theileria|Rep: DNA
replication licensing factor (MCM5 homologue), putative
- Theileria annulata
Length = 770
Score = 223 bits (546), Expect = 1e-56
Identities = 138/353 (39%), Positives = 196/353 (55%), Gaps = 32/353 (9%)
Query: 327 NLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQ 386
+++ + S+ PSI+G ++VK+ LFGG K G +RGDIN+ I+GDPS AKSQ
Sbjct: 371 DIHTKIFNSIAPSIYGLDDVKKACACALFGGTRKEVGNGAKIRGDINILILGDPSIAKSQ 430
Query: 387 LLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDK 446
+LK + I P ++YTSGK SSAAGLTAAVVRD F +E GA++LAD GV CIDEFDK
Sbjct: 431 ILKFIDFIAPISIYTSGKGSSAAGLTAAVVRDSMGV-FSLEGGAMVLADGGVVCIDEFDK 489
Query: 447 MDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP------------------- 487
M P D VAIHEAMEQQTIS++KAG+ LN R S++AAANP
Sbjct: 490 MRPDDAVAIHEAMEQQTISISKAGITTILNTRCSVIAAANPNLGNFTTQIKLDISIDLNF 549
Query: 488 -------IGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCN 540
I G Y+ + + I+SRFDL F+L D D + + I+ LH N
Sbjct: 550 NFLILNLILGSYNNYQDNNEQHDFKTTILSRFDLIFMLKDNEDINHDKLLCKHILSLHNN 609
Query: 541 K-EESYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWR-- 596
+ +++ S + L R+I +++ P+++ EA L +Y +
Sbjct: 610 QNKQNVVGPISNNKLRRFIQYSKQVVSPILSNEAKDSLRNFYVQKRKEYREDKRSSTKKI 669
Query: 597 -ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLD 648
IT+RQLES+VR++E +A+M S + HV A +L S + +++D
Sbjct: 670 PITLRQLESLVRVSESLARMELSPIASEKHVQMAIQLFIVSTGEAMKSTLNVD 722
Score = 34.7 bits (76), Expect = 9.9
Identities = 17/58 (29%), Positives = 32/58 (55%)
Query: 173 FMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTL 230
+++ ++ FVD Q +++QE ++P G +PR L++ + + V GDR G L
Sbjct: 264 YVIIVNECQFVDVQLLKMQELAEDVPTGDMPRHLQLNVTRYLCDKVIPGDRIYAHGVL 321
>UniRef50_Q4UCK0 Cluster: DNA replication licensing factor (MCM7
homolog), putative; n=2; Theileria|Rep: DNA replication
licensing factor (MCM7 homolog), putative - Theileria
annulata
Length = 827
Score = 223 bits (545), Expect = 1e-56
Identities = 107/215 (49%), Positives = 156/215 (72%)
Query: 318 KVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIV 377
K+ E+SR N+Y L S+ P I+G+ ++K+ +LL L GG +G +RG+I++ ++
Sbjct: 360 KMEELSRTPNVYEILSNSIAPDIYGHQDIKKALLLQLIGGCNVVKKDGGFIRGNIHILLL 419
Query: 378 GDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNG 437
GDP AKSQL+K++ +I+ RA+YT+GK SS++GLTAA+V+D + D V+E GAL+LA+NG
Sbjct: 420 GDPGVAKSQLMKRICQISTRAIYTTGKGSSSSGLTAAIVKDPVTGDSVLEGGALVLANNG 479
Query: 438 VCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKS 497
VCCIDEFDKMD D+ AI+E MEQQ +S+AKAG TL A +S+LAAANP+ G YD KS
Sbjct: 480 VCCIDEFDKMDDEDRSAIYEVMEQQKVSVAKAGHVTTLAANSSVLAAANPLSGVYDINKS 539
Query: 498 LQQNVALSPPIMSRFDLFFILIDESSEMVDYAIAR 532
+ N+ L ++SRFDL F+L+D + DY +++
Sbjct: 540 VFININLPHALLSRFDLQFLLLDNINYNNDYKLSQ 574
>UniRef50_A0BNH6 Cluster: Chromosome undetermined scaffold_118,
whole genome shotgun sequence; n=2;
Oligohymenophorea|Rep: Chromosome undetermined
scaffold_118, whole genome shotgun sequence - Paramecium
tetraurelia
Length = 985
Score = 222 bits (542), Expect = 3e-56
Identities = 105/222 (47%), Positives = 154/222 (69%)
Query: 317 DKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCI 376
D++ ++S++ + + S+ PSI+G+ VK + L +FGG AK +RGDINV +
Sbjct: 541 DEILKLSQNPKIDKLIFNSVAPSIYGHQHVKMAIALAMFGGEAKDIQGKHRIRGDINVLV 600
Query: 377 VGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADN 436
+GDP TAKSQ LK V + R++YT+GK +SA GLTA+V RD + ++ I GAL+LAD
Sbjct: 601 LGDPGTAKSQFLKNVQKTFYRSIYTTGKGASAVGLTASVQRDYSTNEWSISGGALVLADK 660
Query: 437 GVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAK 496
G+C IDEFDKM+ D+ +IHEAMEQQ+IS++KAG+ TL AR S++AAANP+GG+YD +
Sbjct: 661 GICLIDEFDKMNEHDRTSIHEAMEQQSISISKAGIVTTLQARCSVIAAANPVGGKYDSQQ 720
Query: 497 SLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
S NV L+ PI+SRFD+ ++ DE + D +A +++ H
Sbjct: 721 SFHDNVDLTDPILSRFDILCVVKDEVIKEADDRLASFVINSH 762
Score = 65.3 bits (152), Expect = 6e-09
Identities = 55/225 (24%), Positives = 100/225 (44%), Gaps = 21/225 (9%)
Query: 22 QKLFQDFLEEFKE--DNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYR 79
++ F+ L E K D E Y + KE+ K +LEV + D+ N +A + EE
Sbjct: 275 KRAFRKILNECKRGSDQEPIYIQLIKEMCKANKQSLEVLYPDLVSANATIALWVAEEPKI 334
Query: 80 IYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQ 139
I P LN A + + + +E +V ++P +R+L + IR+ G
Sbjct: 335 ILPHLNEAAR---IEVNKRFNHYHNIHQEIFVRITNLPVVDIIRDLRYKHLDKFIRVIGV 391
Query: 140 IVRTHPVHPELVQGTFYTI-------PTICRNP---------VCANRRRFMLDADKSVFV 183
+ R V+ +L + T+ + P N C + F ++ V+
Sbjct: 392 VTRRSAVYSQLKEITYVCVKCGMKKGPFYLENNDSIQLGVCIQCQSSGPFEKLYNQLVYR 451
Query: 184 DFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
+FQ++ +QE+ ++P G +PR EVI+ + ++ + GD + TG
Sbjct: 452 NFQRLTLQESPGQVPAGRVPRQKEVIVLGDQIDIARPGDEIEVTG 496
>UniRef50_Q5B060 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 556
Score = 219 bits (534), Expect = 3e-55
Identities = 173/502 (34%), Positives = 246/502 (49%), Gaps = 70/502 (13%)
Query: 144 HPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIP 203
H V ++ +G PTIC C R + ++ VF D Q I++QET +P G P
Sbjct: 13 HSVQVDIDRGKIAE-PTICPRQACQERNSMEIVHNRCVFADKQVIKLQETPDSIPDGQTP 71
Query: 204 RSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGI 263
S+ + + E V+ +AGDR + TG P P R + T
Sbjct: 72 HSVSLCVYDELVDVCKAGDRVEVTGIFRSNP---VRVNPRQRTQKTLFKTY--------- 119
Query: 264 KGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMS 323
+ L V+++ K L V V + +E D E +RK ++E +K+ S
Sbjct: 120 --IDVLHVQKIDRKK--LGIDVSTVEQEL--SEQAAGD--AEQIRKISAEEE-EKILRTS 170
Query: 324 RDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEG--TTLRGDINVCIVGDPS 381
+LY L SL PSI+ ++VK+G+LL LFGG K+ +G RGDINV + GDPS
Sbjct: 171 TRPDLYELLARSLAPSIYEMDDVKKGILLQLFGGTNKSFQKGGNPRYRGDINVLLCGDPS 230
Query: 382 TAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCI 441
T+KSQLL+ SSA GLTA V RD E+ V+E+GAL+L+D GVCCI
Sbjct: 231 TSKSQLLRY--------------GSSAVGLTAYVTRDPETRQMVLESGALVLSDGGVCCI 276
Query: 442 DEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQN 501
DEFDKM+ + +I LA+ANPIG RY+ + QN
Sbjct: 277 DEFDKMNESTRTSI--------------------------LASANPIGSRYNPNLPVPQN 310
Query: 502 VALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCN---KEESYDCVYSRDDLLRYI 558
+ L P ++SRFDL ++++D E D +A+ IV+++ + S V + L YI
Sbjct: 311 IDLPPTLLSRFDLVYLVLDRVDESEDRRLAKHIVNMYLEDRPENASEREVLPVEFLTAYI 370
Query: 559 AFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRI--TVRQLESMVRLAEGVAKM 615
+A++ PV+T AGK L + Y RI T RQLESM+RL+E A+M
Sbjct: 371 TYAKTKVHPVLTPAAGKALTDAYVSMRKLGDDIRSSDRRITATTRQLESMIRLSEAHARM 430
Query: 616 HCSGHVTPAHVHEAYRLLNKSI 637
S VT V EA RL+ +I
Sbjct: 431 RLSAEVTADDVEEAVRLIRSAI 452
>UniRef50_Q24849 Cluster: DNA replication licensing factor MCM3;
n=2; Entamoeba histolytica|Rep: DNA replication
licensing factor MCM3 - Entamoeba histolytica
Length = 597
Score = 218 bits (533), Expect = 4e-55
Identities = 102/236 (43%), Positives = 159/236 (67%), Gaps = 1/236 (0%)
Query: 303 TTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTT 362
T + ++T+ + + + ++ ++ N N S+ PSI+G+++VK+ +LLML G K
Sbjct: 155 TLQSEGPELTEIDKENIKKVMKEENPINLFSKSIAPSIYGHSDVKKAILLMLVGATPKIR 214
Query: 363 IEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESF 422
+ + +RGDI+V + GDPSTAKSQLL+ V I P AV T+G+ ++ GLTAAVV D ++
Sbjct: 215 LR-SRVRGDIHVMLCGDPSTAKSQLLRYVMSIAPLAVSTNGRGATGVGLTAAVVNDPDTN 273
Query: 423 DFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSIL 482
+EAGA++LAD G+CC+DEFDKM D+ A+HE MEQQT+++ KAG+ + + SIL
Sbjct: 274 QRTLEAGAMVLADRGICCVDEFDKMSIEDRAAMHEVMEQQTVTVQKAGIHTGIKCKMSIL 333
Query: 483 AAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
AAANP G YD KS +N+ ++SRFDL FI++D S+E +D +++ ++ +H
Sbjct: 334 AAANPSNGNYDFKKSPMENLYFPESLLSRFDLIFIILDSSTEELDRKLSQHVLKMH 389
Score = 42.3 bits (95), Expect = 0.049
Identities = 22/56 (39%), Positives = 31/56 (55%)
Query: 175 LDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTL 230
L+ S + DFQ + +QE P G +PRS+ VIL + V+ + GDR GTL
Sbjct: 77 LEPGLSTYKDFQTLVVQEMPESAPTGQMPRSVIVILLDQLVDKGKPGDRVIINGTL 132
>UniRef50_Q01EH7 Cluster: Prolifera protein; n=1; Ostreococcus
tauri|Rep: Prolifera protein - Ostreococcus tauri
Length = 451
Score = 218 bits (532), Expect = 6e-55
Identities = 120/300 (40%), Positives = 178/300 (59%), Gaps = 14/300 (4%)
Query: 340 IHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAV 399
I+G+ +VK+ +LL+L GGV ++ LR ++ ++SQLLK + I PRAV
Sbjct: 83 IYGHVDVKKALLLLLCGGVRESF--RMVLRSEV---------ISRSQLLKHIVSIAPRAV 131
Query: 400 YTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAM 459
YT+G+ SS GLTA++ RD + + ++E GAL+LAD G+CCIDEFDKMD D+ AIHE M
Sbjct: 132 YTTGRGSSGVGLTASIQRDTVTTELILEGGALVLADRGICCIDEFDKMDESDRTAIHEVM 191
Query: 460 EQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILI 519
EQQT+S+AKAG+ TLNART++LAAANP GRY+ + + Q+N+ L ++SRFDL ++++
Sbjct: 192 EQQTVSIAKAGITTTLNARTTVLAAANPAFGRYNTSATPQENINLPAALLSRFDLMWLIL 251
Query: 520 DESSEMVDYAIARKIVDLHCNKEESYDCV--YSRDDLLRYIAFARSFKPVITEEAGKLLV 577
D D +AR ++ +H + S +L YI+ AR F+P I E+ +
Sbjct: 252 DTPDPDSDVELARHVMCVHREGRPPLNSFNPASASELRTYISIARRFEPYIPEDVSDSIA 311
Query: 578 -EYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKS 636
Y T R L S++RLAE +A++ S V V +A +L+ S
Sbjct: 312 GAYVGIRQAEDEAGNEATGYTTARTLLSIIRLAEALARLRWSTVVYEKDVEQALKLMKMS 371
>UniRef50_Q54RN8 Cluster: MCM family protein; n=1; Dictyostelium
discoideum AX4|Rep: MCM family protein - Dictyostelium
discoideum AX4
Length = 812
Score = 217 bits (531), Expect = 7e-55
Identities = 107/232 (46%), Positives = 157/232 (67%), Gaps = 6/232 (2%)
Query: 314 KEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGT-----TL 368
K+ + E++ N++ + S+ P+I+G+ VK G+ L LFGG + G+ ++
Sbjct: 355 KDMYGIKEIAEHPNIFKLISNSICPTIYGHELVKAGLTLALFGGSPNRSSNGSDKNKLSI 414
Query: 369 RGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEA 428
R D +V IVGDP KSQ+L + ++PR VY G SS GLT ++R++ S DF IEA
Sbjct: 415 RSDPHVLIVGDPGLGKSQMLTSIYHLSPRGVYVCGGYSSTTGLTVTLLREKGSGDFAIEA 474
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPI 488
GAL+LAD G CCIDEFDKM + A+ EAMEQQ++S+AKAG+ L ARTS++AAANP+
Sbjct: 475 GALVLADQGCCCIDEFDKMTD-EHPALLEAMEQQSVSIAKAGIVCNLPARTSVVAAANPV 533
Query: 489 GGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCN 540
GG Y+RAK++ +N+ +S P++SRFDL FIL+D+ + D+ I+ I++LH N
Sbjct: 534 GGHYNRAKTVSENIKMSAPLLSRFDLIFILMDKPNTEKDHIISHNILNLHSN 585
Score = 44.8 bits (101), Expect = 0.009
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Query: 157 TIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVE 216
T P+ C N C + F D +V +D+QKIRIQE + IP++ E + E VE
Sbjct: 235 TFPSNCLNHGCRGKI-FEPDRSTAVTIDWQKIRIQEDADQKESSGIPKAFECEITDEMVE 293
Query: 217 SVQAGDRYDFTGTLIVV 233
++ GD +G + V+
Sbjct: 294 TIVPGDIVTISGVVKVL 310
Score = 43.6 bits (98), Expect = 0.021
Identities = 25/86 (29%), Positives = 45/86 (52%), Gaps = 3/86 (3%)
Query: 554 LLRYIAFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612
L +YI++A+ + P ++EEA K++ ++Y +T RQLES++RLAE
Sbjct: 642 LRKYISYAKKYVSPRLSEEAIKVIQKFYLELRSKSTGSDSMP--VTTRQLESLIRLAEAR 699
Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638
AK+ VT + ++ S++
Sbjct: 700 AKLELRETVTEQDAIDIVEIMRDSLL 725
>UniRef50_Q74MT7 Cluster: NEQ282; n=1; Nanoarchaeum equitans|Rep:
NEQ282 - Nanoarchaeum equitans
Length = 657
Score = 217 bits (530), Expect = 1e-54
Identities = 115/309 (37%), Positives = 188/309 (60%), Gaps = 6/309 (1%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRG 370
+T+K+ ++ E++ N + L+ + PSI G + +K+ +LL + GGV K +GT +RG
Sbjct: 247 ITNKDLVEIKEIANSNNPLDLLVENFAPSIFGYDYIKKAILLQMVGGVKKIRRDGTKVRG 306
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGA 430
I++ +VGDP TAKS LLK +E+ PR Y SG +++A GL A VVRDE + I+AG
Sbjct: 307 HIHILLVGDPGTAKSTLLKYAAEVAPRGRYVSGTSATAVGLVAVVVRDELLKVWSIDAGP 366
Query: 431 LMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGG 490
++LA+ G+ +DE +K+ + + +HEAMEQ +++++KAG+ TL TS+LAAANP G
Sbjct: 367 MVLANGGLLALDEIEKLGKNELMILHEAMEQGSVTISKAGIHVTLKTETSVLAAANPKFG 426
Query: 491 RYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYS 550
R+D SL + +A+ P I++RFDL F++ D+ + D +A ++++ + E D
Sbjct: 427 RWDDNLSLVEQIAIPPTILNRFDLIFLIRDKPGKDYDEQLAERVLESYV---EDVDLAIP 483
Query: 551 RDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLA 609
D L +YI + R + KP ++ EA + +++ I+ RQLES+VRLA
Sbjct: 484 VDLLRKYILYVRKNIKPRLSNEAIARIKDFFVSLREKSQELKAV--PISTRQLESIVRLA 541
Query: 610 EGVAKMHCS 618
E A++ S
Sbjct: 542 EASARIRFS 550
>UniRef50_Q9GR05 Cluster: DNA replication licensing factor MCM2;
n=8; Plasmodium|Rep: DNA replication licensing factor
MCM2 - Plasmodium falciparum
Length = 971
Score = 213 bits (520), Expect = 2e-53
Identities = 198/678 (29%), Positives = 326/678 (48%), Gaps = 75/678 (11%)
Query: 13 VKDEVGIRCQKLFQDFLEEFKEDNEIKY--EKHAKELLKPELSTLEVSFDDVEKYN-QNL 69
+KD +G+ + + EE ++ +Y +K K +L + TL VS + +++ +NL
Sbjct: 199 LKDSMGLNIDESNTELHEEEHMNSSHQYYIDKIEKMILNDK-HTLIVSAKHLIQFHCENL 257
Query: 70 ATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAK 129
I + +I L+ ++ ++ K + + C V D P ++R L +
Sbjct: 258 VQWIEFKPEQILEVLHECLMVEAYRISP----KLYKGRICKVVLRDWPYSTQLRNLRCTE 313
Query: 130 IGTLIRISGQIVRTHPVHPEL---------VQGTFYTIPTIC---RNPVCANR------R 171
+ TLI+++G ++ V P+L T +P + PV R
Sbjct: 314 LNTLIKVTGVCIKRGYVLPKLRVMYLKCNSCDTTLSEVPIYFADGKKPVLPRRCPHCQSA 373
Query: 172 RFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLI 231
F +D K+ + D+QKI +QE+ +P G PR EV++ + V+ V+ G+ + G
Sbjct: 374 TFSVDRIKTAYTDYQKITLQESPCSVPAGRAPRQREVVVTGDLVDKVKPGEEVEVLGIYK 433
Query: 232 VVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRR 291
D+G L++ + T + N + E I+ L L E K + R
Sbjct: 434 TKYDIG-LNIKYGFPILQTEIEANNIERKEDIQ-LSEL--TEDDIKDILKLSKDPNIRER 489
Query: 292 FGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVL 351
T+ P +D++ + + V + D++ N T+ F R +L
Sbjct: 490 IITSIAPA-IWGHKDIKTSIAYALFGGV-QKGGDKSFSKNNETNNF------GVQNRDIL 541
Query: 352 LMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGL 411
GG TI G DINV ++GDP KSQ+L+ V + R VYT+GK +SA GL
Sbjct: 542 NNFKGG---HTIRG-----DINVLLLGDPGLGKSQVLQYVHKTNLRTVYTTGKGASAVGL 593
Query: 412 TAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGV 471
TA V +D + ++ +E GAL+LAD G+C IDEFDKM D+V+IHEAMEQQ+IS++KAG+
Sbjct: 594 TAGVRKDHTTNEWTLEGGALVLADEGICIIDEFDKMTDKDRVSIHEAMEQQSISISKAGI 653
Query: 472 RATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIA 531
TL AR +++AAANPI GRY+ + + ++NV LS PI+SRFDL +L D + D+ +A
Sbjct: 654 VTTLRARCAVIAAANPIYGRYNPSLTFKENVDLSDPILSRFDLITVLRDIPNVDEDFYLA 713
Query: 532 RKIVDLH------CNKEESY--------DCVYS--------RDDLLRYIAFAR-SFKPVI 568
+V H ++Y + + S +D L +YI +AR + KP +
Sbjct: 714 EYVVTNHQLSHPKLENTQNYQKRIENLKNVIVSSSAYEPIPQDLLQKYIIYARTNCKPSL 773
Query: 569 TE----EAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPA 624
++ E L +Y + +T+R +ES++R+AE AKM S +
Sbjct: 774 SDVPYAEISAKLSNFY--SRVRQKACASGGYPLTLRHIESIIRIAEANAKMRLSHQIYSK 831
Query: 625 HVHEAYRLLNKSIIRVEQ 642
V A L +S + ++
Sbjct: 832 DVDYAIATLLESYVSCQR 849
>UniRef50_UPI000049A27A Cluster: DNA replication licensing factor;
n=1; Entamoeba histolytica HM-1:IMSS|Rep: DNA
replication licensing factor - Entamoeba histolytica
HM-1:IMSS
Length = 733
Score = 211 bits (515), Expect = 6e-53
Identities = 101/232 (43%), Positives = 151/232 (65%), Gaps = 2/232 (0%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
+ ++K+ + + NL L+ SL P I+G+ VK ++L+LFGG K I +R
Sbjct: 282 EFSEKDMKFIEILKEKNNLLRLLVHSLCPPIYGHYIVKTAIVLVLFGGTRKHDI--AKIR 339
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
D ++ IVGDP KSQ+L+ V+ I PR VY SG +++ GLT A+ R + DF +E+G
Sbjct: 340 ADSHLLIVGDPGLGKSQMLRAVANIVPRGVYVSGSSTTKTGLTVALHRYSGTSDFTLESG 399
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489
AL+L D GVCCIDEFDKM+ D ++ EAMEQQ+IS+AKAG+ TL ARTS++AAANP+
Sbjct: 400 ALVLGDQGVCCIDEFDKMERADYSSLLEAMEQQSISIAKAGICCTLLARTSVIAAANPVE 459
Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNK 541
G ++ K++ +N+ + P++SRFDL F+L+D D ++ I+ +H K
Sbjct: 460 GHFNCGKTVSENINMPSPLLSRFDLIFVLVDNPDAEADKELSNHIIKMHSGK 511
Score = 46.8 bits (106), Expect = 0.002
Identities = 56/214 (26%), Positives = 91/214 (42%), Gaps = 30/214 (14%)
Query: 39 KYEK--HAKELLKPELSTLEVSFDDVEKY--NQNLATTIIEEYYRIYPFLNRAILNYILS 94
K+E+ HA+E L + + DD+ ++ + E+ + P + A ++Y+ +
Sbjct: 34 KFEEYVHAEEFLGHSEVGMNIQLDDLIAMVGEEDFKEMLFEKPEIVIPSIEYA-MHYV-A 91
Query: 95 LAETGMKKDLQDKECYVSFVDVPT-RHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQG 153
L + D C V V +P ++EL + IG LI I G ++R + P LV
Sbjct: 92 LHSASDPSQIMDCRCIVR-VQIPKPTSTIKELKASSIGKLICIKGTVIRASSIKPHLVSM 150
Query: 154 TF-----------------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAE 196
F YT P C +C + F+ + + Q+IRIQE +
Sbjct: 151 VFCCSTCKANKEVTFRDGKYTEPKKCH--LCGS-SSFIPMRNTVKVTETQRIRIQE--VD 205
Query: 197 LPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTL 230
G IPRS+E+ L E V + GD +G L
Sbjct: 206 EGEGRIPRSIEIELVNELVNTCVPGDTVIVSGVL 239
Score = 36.3 bits (80), Expect = 3.2
Identities = 22/63 (34%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Query: 556 RYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAK 614
+Y+A+AR+ P + EEA L +Y +T RQLES++RL E AK
Sbjct: 562 KYLAYARANIHPQLNEEAKLELQRFYIELRQSYKEDDDTP--VTTRQLESLIRLTEARAK 619
Query: 615 MHC 617
C
Sbjct: 620 AEC 622
>UniRef50_Q4RLI6 Cluster: Chromosome undetermined SCAF15020, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF15020,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 965
Score = 211 bits (515), Expect = 6e-53
Identities = 111/259 (42%), Positives = 164/259 (63%), Gaps = 24/259 (9%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTT-----IE 364
++TD++ + +S+D + + S+ PSI+G+ ++KR + L LFGG K +
Sbjct: 464 ELTDEDVKAIVALSKDEQIGERIFASMAPSIYGHEDIKRALALSLFGGEPKNPGRSLKLS 523
Query: 365 GTT-------------------LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKA 405
G+T +RGDINV + GDP TAKSQ LK V ++ RAV+T+G+
Sbjct: 524 GSTWSSVMFLIASVVSPGGKHKVRGDINVLLCGDPGTAKSQFLKYVEKVASRAVFTTGQG 583
Query: 406 SSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTIS 465
+SA GLTA V R S ++ +EAGAL+LAD+GVC IDEFDKM+ D+ +IHEAMEQQ+IS
Sbjct: 584 ASAVGLTAYVQRHPVSREWTLEAGALVLADHGVCLIDEFDKMNDADRTSIHEAMEQQSIS 643
Query: 466 LAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEM 525
++KAG+ +L AR +++AA NPIGGRYD + + +NV L+ PI+SRFD+ ++ D ++
Sbjct: 644 ISKAGIVTSLQARCTVIAACNPIGGRYDPSLTFAENVDLTEPIVSRFDVLCVVRDTVDQV 703
Query: 526 VDYAIARKIVDLHCNKEES 544
D +AR +V H S
Sbjct: 704 QDEMLARFVVGSHIKHHPS 722
Score = 65.7 bits (153), Expect = 5e-09
Identities = 55/223 (24%), Positives = 104/223 (46%), Gaps = 24/223 (10%)
Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83
F++FL ++N +++ ++ K +L V+++D+ LA + E +
Sbjct: 208 FKNFLRTHVDENGHNVFKEKISDMCKENKESLVVNYEDLAAREHVLAYFLPEAPAEMLKI 267
Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143
+ A +L++ K D E +V ++P ++R L + LIR SG +
Sbjct: 268 FDEAAKEVVLAMYP---KYDRIAHEIHVRICNLPLVEEIRSLRQLHLNQLIRTSGVVSSC 324
Query: 144 HPVHPEL------------VQGTFYTI------PTICRNPVCANRRRFMLDADKSVFVDF 185
V P+L V G F+ P C P C ++ F ++ +++V+ ++
Sbjct: 325 TGVLPQLGMVKYNCNKCNFVLGPFFQSQNQEVKPGSC--PECQSQGPFEINMEETVYQNY 382
Query: 186 QKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
Q+I IQE+ ++ G +PRS + IL A+ V+S + GD + TG
Sbjct: 383 QRISIQESPGKVAAGRLPRSKDAILLADLVDSCKPGDEIELTG 425
Score = 40.7 bits (91), Expect = 0.15
Identities = 20/46 (43%), Positives = 30/46 (65%)
Query: 597 ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642
ITVR +ESM+R+AE AKMH +V V+ A R++ +S I ++
Sbjct: 823 ITVRHIESMIRMAEAHAKMHLRDYVLEDDVNMAIRVMLESFIDTQK 868
>UniRef50_Q22GD2 Cluster: MCM2/3/5 family protein; n=1; Tetrahymena
thermophila SB210|Rep: MCM2/3/5 family protein -
Tetrahymena thermophila SB210
Length = 759
Score = 210 bits (513), Expect = 1e-52
Identities = 124/321 (38%), Positives = 191/321 (59%), Gaps = 21/321 (6%)
Query: 309 KQMTDKEWDKVYEMSRDRNLY----NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364
K ++E D Y+ RD N LI S P I N++K VLL L GGV++
Sbjct: 386 KSTLEEELDNFYKKQRDLTTEIAARNQLIQSSCPDIFEKNDIKLAVLLCLIGGVSRIE-N 444
Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDF 424
T +RG ++ +VG+P T KSQ+LK ++++ R+V+T+G S++AGLT + + E+ ++
Sbjct: 445 NTRIRGQCHMMLVGEPGTGKSQILKYATKLSNRSVFTTGIGSTSAGLTVSFTK-EQGGEW 503
Query: 425 VIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAA 484
++EAGAL+LAD GVCCIDEF+ + GD ++ EAMEQQTIS +KAG+ + LN+RT+ILAA
Sbjct: 504 IMEAGALVLADMGVCCIDEFNLIKKGDHDSVLEAMEQQTISASKAGITSKLNSRTTILAA 563
Query: 485 ANPI--GGRYDRAKSLQQNVALSPPIMSRFDLFFIL-----IDESSEMVDYAIAR--KIV 535
NPI G RY + + +N L P++SRFDL FI+ D SE ++ + R K
Sbjct: 564 CNPILPGQRYQTSVDITENTGLQSPLLSRFDLIFIVKDIVNYDADSEACEFILERFMKKE 623
Query: 536 DLHCNKEESYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXX 594
D N + S + ++ + L YI ++ F+P IT +A +L+ +YY
Sbjct: 624 DRTMNYQRS-ESLWEIEKLREYINLVQNKFEPTITSDASQLIQKYYQHLRSIELLHS--- 679
Query: 595 WRITVRQLESMVRLAEGVAKM 615
+ T+R LES+VRL + +++
Sbjct: 680 -KTTIRALESLVRLCQAHSRL 699
>UniRef50_A3B9P9 Cluster: Putative uncharacterized protein; n=4;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 700
Score = 208 bits (508), Expect = 4e-52
Identities = 109/256 (42%), Positives = 163/256 (63%), Gaps = 8/256 (3%)
Query: 330 NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLK 389
N+++ + P I+G VK V L L GGV GT +RG+ ++ +VGDP T KSQ LK
Sbjct: 362 NSILKGICPQIYGLFTVKLAVALTLIGGVQHVDASGTKVRGEPHMLLVGDPGTGKSQFLK 421
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
++++ R+V T+G S++AGLT V+D ++++EAGAL+LAD G+CCIDEFD M
Sbjct: 422 FAAKLSNRSVITTGLGSTSAGLTVTAVKD--GGEWMLEAGALVLADGGLCCIDEFDSMRE 479
Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509
D+ IHEAMEQQTIS+AKAG+ TLN RT++ A NP G+YD +SL N LS P++
Sbjct: 480 HDRTTIHEAMEQQTISIAKAGLVTTLNTRTTVFGATNP-KGQYDPNESLSVNTTLSGPLL 538
Query: 510 SRFDLFFILIDESSEMVDYAIARKIV----DLHCNKEESYDCVYSRDDLLRYIAFARS-F 564
SRFD+ +L+D ++ D ++ I+ + K + +++ L RYI + + F
Sbjct: 539 SRFDIVLVLLDTKNKKWDKIVSSHILAENTEEKKGKTSDPEVMWTLSMLRRYIHYVKQHF 598
Query: 565 KPVITEEAGKLLVEYY 580
KPV+T+EA +++ YY
Sbjct: 599 KPVLTKEAERVISSYY 614
Score = 56.8 bits (131), Expect = 2e-06
Identities = 34/87 (39%), Positives = 45/87 (51%), Gaps = 2/87 (2%)
Query: 146 VHPELVQGTFYTIPTICRNPVC--ANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIP 203
VHPEL G T+P C++ F L D D+Q+I+IQE L G IP
Sbjct: 216 VHPELEAGNRITLPASCKSKSAKGCGGANFQLIEDSITCHDYQEIKIQENIQLLGVGSIP 275
Query: 204 RSLEVILRAEAVESVQAGDRYDFTGTL 230
RS+ +IL + V+ V+AGD TG L
Sbjct: 276 RSMPIILMDDLVDIVKAGDDVVVTGRL 302
>UniRef50_Q4RF39 Cluster: Chromosome 14 SCAF15120, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 14
SCAF15120, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 830
Score = 207 bits (506), Expect = 8e-52
Identities = 108/238 (45%), Positives = 150/238 (63%), Gaps = 25/238 (10%)
Query: 326 RNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKS 385
+ ++ L SL PSIHG+ +K+ +L +L GGV K G+ +RGDIN+ ++GDPS AKS
Sbjct: 277 QGVFEQLANSLAPSIHGHEYIKKAILCLLLGGVEKVLDNGSRIRGDINILLIGDPSVAKS 336
Query: 386 QLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEES---------------------FDF 424
QLL+ V PRA+ T+G+ SS GLTAAV D+E+ F F
Sbjct: 337 QLLRYVLHTAPRAIPTTGRGSSGVGLTAAVTTDQETGTIRANVHGCVRFPADNPPSVFPF 396
Query: 425 V----IEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTS 480
+EAGA++LAD GV CIDEFDKM D+ AIHE MEQ +++AKAG+ A LNAR S
Sbjct: 397 PGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKAGIHARLNARCS 456
Query: 481 ILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
+LAAANP+ GRYD+ K+ +N+ L ++SRFDL FI++D+ D I+ ++ +H
Sbjct: 457 VLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIVLDQMDPEQDREISDHVLRMH 514
Score = 46.8 bits (106), Expect = 0.002
Identities = 22/55 (40%), Positives = 33/55 (60%)
Query: 180 SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVP 234
SV+ D Q I +QE + P G +PRS+++IL + V+ V+ GDR GT +P
Sbjct: 211 SVYKDHQTITVQEMPEKAPAGQLPRSVDIILDNDLVDVVKPGDRVQVVGTYRCLP 265
>UniRef50_UPI000051A385 Cluster: PREDICTED: similar to DNA
replication licensing factor Mcm2 (Minichromosome
maintenance 2 protein) (DmMCM2); n=1; Apis
mellifera|Rep: PREDICTED: similar to DNA replication
licensing factor Mcm2 (Minichromosome maintenance 2
protein) (DmMCM2) - Apis mellifera
Length = 625
Score = 207 bits (505), Expect = 1e-51
Identities = 118/300 (39%), Positives = 176/300 (58%), Gaps = 21/300 (7%)
Query: 330 NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLK 389
+N++ S+ P ++G K + ++L GGV K GT +RG+ ++ +VGDP T KSQLL+
Sbjct: 273 DNILASICPKLYGMYTAKLALAVVLAGGVPKCNESGTRVRGEPHLLLVGDPGTGKSQLLR 332
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
S + R+V T+G S+AAGLTA VRD E + +EAGAL+LAD GVCC+DEF M
Sbjct: 333 AASRLAIRSVLTTGVGSTAAGLTATAVRDSEGWH--LEAGALVLADGGVCCVDEFTTMSS 390
Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509
D+ ++HEAMEQQTIS+AKAG+ +TLN+R S++AA NP GG++ + + N L P++
Sbjct: 391 QDRTSVHEAMEQQTISIAKAGLVSTLNSRCSVVAAINPSGGQFTDDEEWETN--LGDPLL 448
Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES--------------YDCVYSRDDLL 555
SRFDL +L D + D + I+ +E+ + ++ D L
Sbjct: 449 SRFDLILLLKDNRNSEWDRLTSEHILKAAYETKENNAQTDSKNHMELLKSESLWKEDTLR 508
Query: 556 RYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKM 615
Y+A+ S +P +T+EA +L Y R TVR L+S++RLAEG A++
Sbjct: 509 EYLAYVHSLQPKLTKEAEMILRATYLYHRCHPNRREE---RTTVRLLDSLIRLAEGHARL 565
>UniRef50_Q7QPP1 Cluster: GLP_514_10128_7345; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_514_10128_7345 - Giardia lamblia
ATCC 50803
Length = 927
Score = 206 bits (504), Expect = 1e-51
Identities = 133/361 (36%), Positives = 204/361 (56%), Gaps = 29/361 (8%)
Query: 180 SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGAL 239
S+F QKI +Q+ +P G +PRS+ VILR ++ ++GD + G I P V
Sbjct: 220 SLFDSVQKILVQDHPEYVPSGRLPRSIPVILRNHLIDKCKSGDLVEILG--IFNPSVH-- 275
Query: 240 SMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPT 299
RA T+ TK ++ G L AL + L + R TAE
Sbjct: 276 ----HRAGETSNTKSSSIGNF-----LLALSINVLE----------RTPIRHISTAEEHV 316
Query: 300 HDLTTE--DMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGG 357
D+ + M + ++ +S + L S P+I+G+ VKRG++L L G
Sbjct: 317 IRFLKRCTDISRWMRHRNNTQLVSLSG--YALDVLTASFAPAIYGHWIVKRGIVLQLLQG 374
Query: 358 VAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVR 417
V + + +RGDIN+ ++GDP +AKSQ+L+ V ++ P +V T+G+ SS GLTAAVV
Sbjct: 375 VPREFSSSSRIRGDINILLIGDPGSAKSQMLRVVKQLMPVSVQTTGRGSSGVGLTAAVVI 434
Query: 418 DEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNA 477
D + + ++ GA +LAD GV IDEFDK+D D+ +HEA+EQQ+IS++KAG+ TLNA
Sbjct: 435 DGTTGERRLDPGAAVLADKGVLLIDEFDKVDADDRALLHEALEQQSISISKAGLHCTLNA 494
Query: 478 RTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDL 537
R S+LAAANP+ G +D +S +N+AL ++SR+DL F++ D+ + +D IA ++
Sbjct: 495 RCSVLAAANPVYGFFDPKRSFAENIALPDSLLSRYDLVFLVRDDHT--MDAKIASHVLLN 552
Query: 538 H 538
H
Sbjct: 553 H 553
>UniRef50_UPI0000D56719 Cluster: PREDICTED: similar to
minichromosome maintenance protein 8 isoform 1; n=1;
Tribolium castaneum|Rep: PREDICTED: similar to
minichromosome maintenance protein 8 isoform 1 -
Tribolium castaneum
Length = 769
Score = 206 bits (502), Expect = 2e-51
Identities = 121/340 (35%), Positives = 189/340 (55%), Gaps = 36/340 (10%)
Query: 328 LYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQL 387
L+ L+ SL P+I+G+ VK G+LL LFGG + + R + +V +VGDP KSQ+
Sbjct: 348 LFRFLVQSLCPTIYGHEIVKAGLLLALFGGT-----KSSKFRAESHVLMVGDPGIGKSQM 402
Query: 388 LKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKM 447
L + PR VY G S+ +GLT + R+ + ++ +EAGALMLAD G CCIDEFDKM
Sbjct: 403 LHACVNVAPRGVYVCGNTSTGSGLTVTMTREAKG-EYSLEAGALMLADQGCCCIDEFDKM 461
Query: 448 DPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPP 507
P + E MEQQ+IS+AKAG+ TL R +ILAAANP GG Y++AK++ +N+ +S P
Sbjct: 462 -PTQHACLLEVMEQQSISIAKAGIVCTLPTRATILAAANPAGGHYNKAKTIAENLKISSP 520
Query: 508 IMSRFDLFFILIDESSEMVDYAIARKIVDLHCNK-------------------------E 542
++SRFDL FIL+D+ +E +D ++ I+ LH + +
Sbjct: 521 MLSRFDLVFILLDQPNEDLDMRLSEHILALHSRRNGSNVSKNSTLAEGVNNSLRGRLSLQ 580
Query: 543 ESYDCVYSRDDLLR-YIAFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600
+ + Y L R YIA+A+ + P ++++A ++L ++Y +T R
Sbjct: 581 DGEEIDYLPHSLFRKYIAYAQKYVNPQLSDDAKQVLKDFYFQLRKEFQNGDST--PVTTR 638
Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRV 640
QL S++RL + AK T + ++ +++I +
Sbjct: 639 QLNSLMRLTQARAKAELREEATKEDAQDVVEIMRQTLIDI 678
Score = 37.1 bits (82), Expect = 1.9
Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 6/82 (7%)
Query: 156 YTIPTICRNPVCANRRRFMLDADKSVF---VDFQKIRIQET--QAELPRGCIPRSLEVIL 210
+T+P C C R F S F + +Q I+IQE E G +PR+LE L
Sbjct: 207 FTVPNKCLTEGCKARSNFQA-LHSSPFTRTISWQHIKIQELIGNDEFENGRVPRTLECEL 265
Query: 211 RAEAVESVQAGDRYDFTGTLIV 232
+ V S GD TG + V
Sbjct: 266 TEDLVNSCVPGDDVTITGVIKV 287
>UniRef50_UPI00004984D3 Cluster: DNA replication licensing factor;
n=2; Entamoeba histolytica HM-1:IMSS|Rep: DNA
replication licensing factor - Entamoeba histolytica
HM-1:IMSS
Length = 810
Score = 206 bits (502), Expect = 2e-51
Identities = 121/309 (39%), Positives = 185/309 (59%), Gaps = 15/309 (4%)
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTT-LRGDINVCIVGDPSTAKSQLLKQ 390
++ S+ P + G K V+L+ GG+++ E T RG I++ +VGDP T KSQLLK
Sbjct: 205 ILQSICPELCGLRMCKLAVMLVATGGISRIDKESKTKTRGTIHLLLVGDPGTGKSQLLKF 264
Query: 391 VSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPG 450
S++ PR V T+G +++AGLT +V+ + ++AGAL+LAD GVCCIDEF ++
Sbjct: 265 ASKLGPRHVQTTGGGTTSAGLTVSVINI--GGELSLDAGALVLADGGVCCIDEFSGINKS 322
Query: 451 DQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMS 510
D+ IHEAMEQQT+S+AKAG+ + L+ RT+ILAA NP GRYD KS+ N A+ PP++S
Sbjct: 323 DRADIHEAMEQQTLSVAKAGIVSQLHTRTAILAATNP-KGRYDPTKSMSLNTAIDPPLLS 381
Query: 511 RFDLFFILIDESSEMVDYAIARKIVDLH--CNKEESYDCVYSRDDLLRYIAFAR-SFKPV 567
RFD+ +L+D+ S++ D ++ +++ H NK +DC D L YI + + F P
Sbjct: 382 RFDIILLLLDDRSKIWDEQVSDYVLNGHKPINK-PLFDC----DQLQCYILYVKMHFFPE 436
Query: 568 ITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVH 627
+TEEA ++ +Y+ R T+R ES++R+++ AK+ VT
Sbjct: 437 MTEEAELVIQKYFQYQRGKERRESG---RTTIRLFESLIRISQAHAKLMMHQSVTLMDAV 493
Query: 628 EAYRLLNKS 636
A L+ S
Sbjct: 494 MAILLIESS 502
>UniRef50_Q4Q3R6 Cluster: Minichromosome maintenance (MCM) complex
subunit, putative; n=6; Trypanosomatidae|Rep:
Minichromosome maintenance (MCM) complex subunit,
putative - Leishmania major
Length = 881
Score = 206 bits (502), Expect = 2e-51
Identities = 112/235 (47%), Positives = 151/235 (64%), Gaps = 2/235 (0%)
Query: 318 KVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIV 377
K E + L ++ P+I+G K+ +LL++ GGV + + + +RGDINV +V
Sbjct: 314 KCVEQLGPGGVLETLSKAVAPTIYGMTAAKQAILLLMVGGVERKS-HNSHVRGDINVLLV 372
Query: 378 GDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNG 437
G+PSTAKSQLL+ V I P A+ T+GK SS GLTAAV D + + + AGA++LAD G
Sbjct: 373 GEPSTAKSQLLRFVLGIAPLALSTTGKGSSGVGLTAAVATDSYTGERSLSAGAMVLADRG 432
Query: 438 VCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKS 497
+ CIDEFDKM D+VA+HEAMEQQT+++AKAG+ A+LNAR S+LAAANPI G Y
Sbjct: 433 ILCIDEFDKMGSQDRVAMHEAMEQQTVTIAKAGIHASLNARCSVLAAANPIYGFYSVQHR 492
Query: 498 LQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE-SYDCVYSR 551
L NV L ++SRFDL FI++D+ S + I I+ H E YD V SR
Sbjct: 493 LAFNVGLPESLLSRFDLTFIILDQHSSDYNRRIGYHILRNHMTAEAVRYDDVESR 547
Score = 41.1 bits (92), Expect = 0.11
Identities = 26/103 (25%), Positives = 48/103 (46%)
Query: 535 VDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXX 594
+DL + + + S D L ++ A+ P++T+ + L+ ++Y
Sbjct: 590 LDLRMTTNSTGESIVSIDFLRAFLQMAKRGSPLLTDVSRDLVCQHYVQLRAEQQDGGRDG 649
Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
+ IT R L+++VRL+ AK+ S V + V A LL S+
Sbjct: 650 FFITPRTLDAIVRLSTAHAKLRLSPTVEESDVTAAMALLRASV 692
Score = 35.5 bits (78), Expect = 5.7
Identities = 17/48 (35%), Positives = 27/48 (56%)
Query: 181 VFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
+F+D Q +QE P G +PR++EV + V++V+ GDR G
Sbjct: 219 IFMDSQCAVLQEAPERAPTGQLPRNVEVRFDDDLVDAVKPGDRVLLVG 266
>UniRef50_Q8SQX1 Cluster: DNA REPLICATION LICENSING FACTOR MCM4;
n=1; Encephalitozoon cuniculi|Rep: DNA REPLICATION
LICENSING FACTOR MCM4 - Encephalitozoon cuniculi
Length = 681
Score = 205 bits (500), Expect = 4e-51
Identities = 118/338 (34%), Positives = 188/338 (55%), Gaps = 34/338 (10%)
Query: 327 NLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQ 386
N +L+ SL+ +++GN +K G++L LFGG K+ + + +R + +V IVGDP KS+
Sbjct: 285 NTLASLVCSLYSAVYGNELIKVGLVLSLFGGTKKSAGQHS-IRSETHVLIVGDPGLGKSR 343
Query: 387 LLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDK 446
LL I P++ Y SG ++ AGLT ++ D S +++ +AGAL++ADNG+CC+DEFDK
Sbjct: 344 LLLSTCGILPKSSYVSGSFTTTAGLTVSLTHDPVSGEYMADAGALVVADNGICCLDEFDK 403
Query: 447 MDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSP 506
+D D A+ EAME Q +S+AK GV ++ R +++AA NP G +DR K++ +N+ P
Sbjct: 404 ID--DHAALFEAMEDQKVSIAKGGVICSVPTRATVIAATNPRHGHFDRGKTMAENIRFDP 461
Query: 507 PIMSRFDLFFILIDESSEMVDYAIARKIV----------------------DLHCNKEES 544
++SRFDL F+L+D+ SE Y I+ +I+ D+ S
Sbjct: 462 GLLSRFDLIFLLLDDLSEKESYMISGQILKKRRTLSPGEGGFDDVVETVRRDMFVEDIRS 521
Query: 545 YDCVYSRDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLE 603
CVY D + +YI++AR + PV+++ A + + EYY ++ R LE
Sbjct: 522 GGCVYPMDIVRKYISYARANVFPVLSKSASEAIKEYYVGMRSRGG--------VSTRDLE 573
Query: 604 SMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVE 641
S+VRL E AK+ T A L ++ + E
Sbjct: 574 SLVRLTEARAKVELRSIATKADAMFCIELHKRTFVSKE 611
>UniRef50_Q0UXG2 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 386
Score = 205 bits (500), Expect = 4e-51
Identities = 127/336 (37%), Positives = 186/336 (55%), Gaps = 27/336 (8%)
Query: 340 IHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAV 399
I G+ +VK+ +LL L GGV K +G +RGDINVC++GDP AKSQLLK ++++ PR V
Sbjct: 5 IFGHVDVKKALLLQLIGGVTKEVKDGMRIRGDINVCLMGDPGVAKSQLLKYITKVAPRGV 64
Query: 400 YTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAM 459
YT+G+ SS GLTAAV+RD + + V+E GAL+LADN M
Sbjct: 65 YTTGRGSSGVGLTAAVMRDPVTDEMVLEGGALVLADN---------------------VM 103
Query: 460 EQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILI 519
EQQTIS++KAG+ TLNARTSILAAANP+ GRY+ S +N+ L ++SRFD+ F+++
Sbjct: 104 EQQTISISKAGITTTLNARTSILAAANPLYGRYNPRISPVENINLPAALLSRFDVLFLIL 163
Query: 520 DESSEMVDYAIARKIVDLHC-NK--EESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLL 576
D + D +AR + +H NK E V+S ++ +++A ARS++P + +E +
Sbjct: 164 DTPARDSDEELARHVTHVHMHNKHPEVQGGIVFSPAEVRQWVARARSYRPNVPKEVSDYM 223
Query: 577 VEYYXXXXXXXXXXXXXXWRIT---VRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
V Y T R L ++RLA+ +A++ + V V EA RL
Sbjct: 224 VGAYVRMRQQQKRDEGSKKAFTHTSPRTLLGVLRLAQALARLRFADEVISEDVDEALRLT 283
Query: 634 NKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTA 669
S + D D+ P + + E +G A
Sbjct: 284 EVSKASLYADDNRRDDYTPSSKIYHLIKSMEASGAA 319
>UniRef50_Q4N4V8 Cluster: DNA replication licensing factor MCM2,
putative; n=3; Piroplasmida|Rep: DNA replication
licensing factor MCM2, putative - Theileria parva
Length = 967
Score = 204 bits (499), Expect = 6e-51
Identities = 137/376 (36%), Positives = 207/376 (55%), Gaps = 47/376 (12%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAK--------- 360
++TD++ ++ +S+D + LI S+ P++ G+ K VL LFGGV K
Sbjct: 459 ELTDEDVAEIKRLSKDPCIRERLIASVAPTLWGHKTAKASVLSALFGGVPKGILHSVNSG 518
Query: 361 --------------TTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKAS 406
T+ G +RGDINV +VGDP KSQLL+ V + R+V T+GK +
Sbjct: 519 AGNSVNNANGVNTGNTMGGHRIRGDINVLLVGDPGLGKSQLLQYVHKTANRSVLTTGKGA 578
Query: 407 SAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISL 466
SA GLTA V +D + ++ +E GAL+LAD G C IDEFDKM D+V+IHEAMEQQ+IS+
Sbjct: 579 SAVGLTAGVRKDPVTGEWSLEGGALVLADEGFCVIDEFDKMTDKDRVSIHEAMEQQSISI 638
Query: 467 AKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFIL-----IDE 521
+KAG+ +L AR S++AAANP GRY+ A + ++NV S PI+SRFDL +L I+E
Sbjct: 639 SKAGIVTSLRARCSVIAAANPKFGRYEPALTFKENVDFSDPILSRFDLIVVLRDIPNIEE 698
Query: 522 SSEMVDYAIA-RKIVDLHCNKEESYDCVYSR--DDLL--------------RYIAFA-RS 563
+ +Y + +++ + E Y+ V R + LL +Y+ +A R
Sbjct: 699 DLLLSEYVVTNHQLLHPRLDNVEDYENVLKRLQNTLLSSNIVEPLPTEVFKKYVYYARRH 758
Query: 564 FKPVITEE-AGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVT 622
KPVI +E ++ + + +T+R +ES++R++E AKM S +T
Sbjct: 759 VKPVIAQEYYSQIEGKLSGVYSRIRQRTFGGGYPLTLRHIESIIRISEANAKMRLSSVIT 818
Query: 623 PAHVHEAYRLLNKSII 638
V A +L +S I
Sbjct: 819 SDDVDVAIAMLLESYI 834
Score = 62.9 bits (146), Expect = 3e-08
Identities = 63/235 (26%), Positives = 106/235 (45%), Gaps = 26/235 (11%)
Query: 25 FQDFLEEFK--EDN-EIKYEKHAKELLKPELSTLEVSFDDVEKYN-QNLATTIIEEYYRI 80
F+ FL FK ED Y+ +++ + + L V+ + +++ +N+ T + +
Sbjct: 200 FRYFLYRFKLTEDAPNYYYKSKISTMIREDKTVLRVAAQHLLQFHCENVITWLEFRPADV 259
Query: 81 YPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQI 140
P L+ + + L E KK + C V+ D P ++ L ++++ TLIR+SG +
Sbjct: 260 LPVLHDCLTFEVSKLKEELYKK----RYCKVAITDWPFTTQLGLLRSSELNTLIRVSGIV 315
Query: 141 VRTHPVHPEL---------VQGTFYTIPTICRN---PVCANR------RRFMLDADKSVF 182
+R V P L T +P + PV R F +D + +
Sbjct: 316 IRRGSVLPRLRVLYLKCNACDTTLSELPIYFSDVIKPVFPKRCPYCHSPGFNVDRINTEY 375
Query: 183 VDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVG 237
D+QK+ IQE + +P G PR VIL + V+SV+ GD D GT D+G
Sbjct: 376 TDYQKLTIQEPPSSVPAGRTPRQKIVILTGDFVDSVKPGDLVDVLGTYKTRYDLG 430
>UniRef50_A0CQF3 Cluster: Chromosome undetermined scaffold_24, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_24,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 575
Score = 204 bits (497), Expect = 1e-50
Identities = 111/290 (38%), Positives = 179/290 (61%), Gaps = 17/290 (5%)
Query: 330 NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLK 389
N +I S P + +VK G LL L GGV K+ G T+RGD ++ ++G+P T KS L+
Sbjct: 251 NQVINSFIPELCNQWQVKLGTLLSLIGGVTKSN-NGITVRGDSHLLLIGEPGTGKSTFLR 309
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
I+ +++Y +G ++ AGLT + V+ E D++IEAGAL++AD G+CCIDEF+ ++
Sbjct: 310 NACTISEKSIYVNGIGTTQAGLTLSFVK--EGSDWMIEAGALVMADQGLCCIDEFNLLNQ 367
Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509
Q +I EA+EQQTIS +KAG+ LNART+I+AA NP+ Y+ S+Q N LS P++
Sbjct: 368 QSQQSILEALEQQTISSSKAGISTKLNARTTIIAACNPVEQVYNSKLSIQYNSGLSTPLL 427
Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFAR-SFKPVI 568
SRFD +IL D+ +D + I +L+ NK+ Y+ L +YI + + +F+P++
Sbjct: 428 SRFDQIYILKDQHDFELDKQLCDHIFNLNNNKQN-----YTLKQLKQYIIYVKNTFQPIM 482
Query: 569 TEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCS 618
E+ +++ +Y+ ++T R+LES++RL+E A++ CS
Sbjct: 483 NEDCQQVIQKYFTFIRQQTQ-------QVTARKLESLIRLSEAHARL-CS 524
Score = 38.7 bits (86), Expect = 0.61
Identities = 17/45 (37%), Positives = 27/45 (60%)
Query: 178 DKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGD 222
+ S +D+Q+I+IQ+T + G I S+ V+L E V S +GD
Sbjct: 152 EDSKLIDYQEIKIQDTYTTIEPGTISNSIRVMLEGEFVNSCNSGD 196
>UniRef50_A7AR97 Cluster: Minichromosome maintenance protein 3,
putative; n=1; Babesia bovis|Rep: Minichromosome
maintenance protein 3, putative - Babesia bovis
Length = 957
Score = 201 bits (490), Expect = 7e-50
Identities = 97/229 (42%), Positives = 150/229 (65%)
Query: 307 MRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGT 366
+ +++D++ K ++++ + N L S+ PSI G+ VKRG+LL L GG
Sbjct: 389 LSNEISDEDRAKFKQLAQSDDCLNILTRSMAPSICGHEIVKRGILLSLVGGPESDESSDH 448
Query: 367 TLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVI 426
+RGDI+V +VGDP KSQ+L+ V + P V T+G+ S+ GLTAAVV D+++ + +
Sbjct: 449 RIRGDIHVLLVGDPGCGKSQMLRFVMNLLPGTVSTTGRGSTGVGLTAAVVVDQDTGERRV 508
Query: 427 EAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAAN 486
E GA+++ D V CIDEFDKM GD+VAIHE MEQQT+++AKAG+ TLNAR +++AAAN
Sbjct: 509 EGGAMVMGDRRVVCIDEFDKMQAGDRVAIHEVMEQQTVTVAKAGIHTTLNARCTVIAAAN 568
Query: 487 PIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIV 535
P+ G + + Q ++ ++SRFDL F++ D ++E+ D IA ++
Sbjct: 569 PLYGCWSEDMDVSQQLSFERSLISRFDLIFVVRDAATEVEDERIAEAVL 617
>UniRef50_Q7RI91 Cluster: Replication origin activator 2-related;
n=8; Plasmodium|Rep: Replication origin activator
2-related - Plasmodium yoelii yoelii
Length = 997
Score = 200 bits (489), Expect = 9e-50
Identities = 99/232 (42%), Positives = 151/232 (65%), Gaps = 1/232 (0%)
Query: 304 TEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTI 363
T D +++ + + ++ +N + L S PSI G + VK+G++LML GG + +
Sbjct: 369 TYDTNLFISEADKKNFHAFAKKQNTIDILGYSFAPSICGQDIVKKGIVLMLAGGTERA-L 427
Query: 364 EGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD 423
+RGDI++ +VGDPS KSQLL+ V I P V +G+ SS GLTAA+V D+++ +
Sbjct: 428 PSHHIRGDIHIMLVGDPSCGKSQLLRYVMSIMPGTVSATGRGSSGVGLTAAIVTDQDTGE 487
Query: 424 FVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILA 483
V+E GA+++ D V CIDEFDKM D+VAIHE MEQQT+++AKAG+ TLNAR ++LA
Sbjct: 488 RVVEGGAMVMGDRRVVCIDEFDKMQQTDRVAIHEVMEQQTVTVAKAGIHTTLNARCTVLA 547
Query: 484 AANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIV 535
AANP+ G ++ + + Q + P ++SRFDL F++ D ++E D IA ++
Sbjct: 548 AANPLYGCWNDSLDMGQQLQFEPSLLSRFDLIFLVRDSTTEQDDERIAESVL 599
Score = 42.7 bits (96), Expect = 0.037
Identities = 31/119 (26%), Positives = 52/119 (43%), Gaps = 3/119 (2%)
Query: 566 PVITEEAGKLLVEYYXXXXXXXXXXXXXX--WRITVRQLESMVRLAEGVAKMHCSGHVTP 623
P +++EA +++ E Y +T R LE+++R+A AK+ + +VT
Sbjct: 715 PEVSDEACEVITELYADLREKAAKYSHNKIIQGVTPRTLEAIIRIASSHAKLKLNRYVTS 774
Query: 624 AHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTAETPSNGDSAPKKK 682
V+ A +LL ++ E + DE E E D D D+ P N + K K
Sbjct: 775 VDVNYAKKLLMYTLFGEEIVESE-DESEDDEEEDYDDDDDDDEEYLHKPQNKKNKTKSK 832
Score = 36.3 bits (80), Expect = 3.2
Identities = 17/42 (40%), Positives = 26/42 (61%)
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDR 223
+ + QK IQET + P G +PR +EVI+ + + V+ GDR
Sbjct: 290 YKNHQKFVIQETPEDAPTGQMPRWVEVIVEDDLCDIVKCGDR 331
>UniRef50_Q5CTT7 Cluster: DNA replication licensing factor MCM3
like; n=2; Cryptosporidium|Rep: DNA replication
licensing factor MCM3 like - Cryptosporidium parvum Iowa
II
Length = 862
Score = 200 bits (488), Expect = 1e-49
Identities = 102/236 (43%), Positives = 149/236 (63%), Gaps = 1/236 (0%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
++T +E + E+S + + L S S+ G+ +K+G+LL + GG GT +R
Sbjct: 293 ELTPQEIRIMKEISNRDDAFEILSRSFASSLCGHEYIKKGLLLGILGGAEHNLENGTHIR 352
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
GDI+ ++G+PS KSQLL+ V I P A+ T+G+ S GLTAAV D ++ + +EAG
Sbjct: 353 GDIHTLLIGEPSCGKSQLLRFVMSIAPLAISTTGRGCSGVGLTAAVTHDPDTKERRLEAG 412
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489
A +LAD G+ CIDEFDKM D+VAIHE MEQQ +++AKAG++A+LNAR SI AAANP+
Sbjct: 413 ATVLADRGIVCIDEFDKMSFSDRVAIHEVMEQQRVTIAKAGIQASLNARCSIFAAANPVY 472
Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIV-DLHCNKEES 544
G +D L + +A ++SRFDL FI+ D + D IA +++ + NK S
Sbjct: 473 GHFDDFMELSRQIAFPDSLLSRFDLIFIVKDSRNSQQDRKIAAQVLAQVRYNKNSS 528
Score = 43.2 bits (97), Expect = 0.028
Identities = 18/47 (38%), Positives = 29/47 (61%)
Query: 182 FVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
+ D QK+ +QE +P G +PRS+E+I + VE+++ GDR G
Sbjct: 210 YKDTQKMTLQELPEMIPTGQLPRSIEIIAEDDLVETIKPGDRVKIVG 256
>UniRef50_Q5V011 Cluster: MCM / cell division control protein 21;
n=2; Halobacteriaceae|Rep: MCM / cell division control
protein 21 - Haloarcula marismortui (Halobacterium
marismortui)
Length = 681
Score = 198 bits (483), Expect = 5e-49
Identities = 117/329 (35%), Positives = 186/329 (56%), Gaps = 17/329 (5%)
Query: 329 YNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLL 388
Y LI S+ P G+ VK V L LFGG A +G+ RGD ++ ++GDP KS L
Sbjct: 275 YQLLIDSINPKHRGDEHVKLAVALQLFGGWAHEYPDGSRDRGDCHMLLLGDPGCGKSTFL 334
Query: 389 KQVSEITPRAVYTSGKASSAAGLTAAVVRDE-ESFDFVIEAGALMLADNGVCCIDEFDKM 447
+ V +I PR+ Y SGK ++AAG+TAA V D+ ++ +EAGAL+LAD G+ C+DE DKM
Sbjct: 335 RYVDQIAPRSTYASGKGATAAGMTAAAVSDDFGDTEWGLEAGALVLADGGIACVDEIDKM 394
Query: 448 DPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPP 507
++H+A+E Q + + KAG+ ATLNARTS+LAA NP GR+DR + + + + P
Sbjct: 395 QSDAVSSMHDALESQQVHVNKAGINATLNARTSLLAAGNPKDGRFDRYRPKGEQIDMGPT 454
Query: 508 IMSRFDLFFILIDE-----SSEMVDYAI-ARKIVDLHC-------NKEESYDCVYSRDDL 554
++SRFDL F++ DE +++V++ + +R+ H +++ + R +
Sbjct: 455 LLSRFDLMFMVSDEPDREDDADVVEHMLQSRQAAGRHTRGENLSEEEQKRVEPAIDRSVM 514
Query: 555 LRYIAFARSF-KPVI-TEEAGKLLVEYYXXXXXXXXXXXXXX-WRITVRQLESMVRLAEG 611
YIA A+ P+I EE + L +++ +T R++E++ RLAE
Sbjct: 515 RAYIAHAKQICHPIIEDEEVAERLKQFFVEFRAGAGEQDDDSPIPVTFRKVEAIQRLAES 574
Query: 612 VAKMHCSGHVTPAHVHEAYRLLNKSIIRV 640
A++ S V + A +L+ KS+ +V
Sbjct: 575 SARVRLSDTVEIEDIERAIKLVTKSMRQV 603
Score = 48.4 bits (110), Expect = 8e-04
Identities = 53/198 (26%), Positives = 84/198 (42%), Gaps = 26/198 (13%)
Query: 51 ELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECY 110
E +L V +DD+ +++ +A + + L A+ Y L +A +L D +
Sbjct: 33 EQKSLHVDYDDLYRFDPGIADDVRNHPKELQEHLEEALRLYDLPVAV-----ELND--AH 85
Query: 111 VSFVDVPTRHKVRELTTAK---IGTLIRISGQIVRTHPVHPELVQ--------GTFYTIP 159
V ++P H ++ IG L+ I GQ+ + V P L + GT IP
Sbjct: 86 VRIYNLPEIHVFDPSGVSRHENIGQLLDIRGQVQKVSDVKPRLTEAVWECQRCGTQTEIP 145
Query: 160 T---ICRNPV----CANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRA 212
+ P C + F LDA S ++D Q RIQ+ E G +S++ L
Sbjct: 146 QHGDSLQEPHECQGCERQGPFSLDASASSWIDHQYARIQQ-PPEKTNGGEAQSVDAHLED 204
Query: 213 EAVESVQAGDRYDFTGTL 230
+ +E AGDR TG L
Sbjct: 205 DLIEGFDAGDRVVLTGVL 222
>UniRef50_Q17DG5 Cluster: DNA replication licensing factor MCM8;
n=2; Culicidae|Rep: DNA replication licensing factor
MCM8 - Aedes aegypti (Yellowfever mosquito)
Length = 845
Score = 198 bits (482), Expect = 6e-49
Identities = 103/229 (44%), Positives = 151/229 (65%), Gaps = 6/229 (2%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
+ +D + + + + + + L+ SL P I+G+ +K G+LL LFGG + T +G R
Sbjct: 399 EFSDLDMEAIRMIRSEPCPFRLLVQSLCPMIYGHEMIKAGLLLGLFGGASIT--KGR--R 454
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
+I+V IVGDP KSQ+L+ +E++PR ++ G ++S AGLT AV R E+ +EAG
Sbjct: 455 SEIHVLIVGDPGIGKSQMLQSCAEVSPRGIFVCGNSTSNAGLTVAV-RTEKCTGGALEAG 513
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489
AL+LAD G CCIDEFDKM Q+ + EAMEQQ +S+AKAGV +L ART ILAAANP G
Sbjct: 514 ALVLADQGACCIDEFDKMSGNHQILL-EAMEQQVVSVAKAGVICSLPARTCILAAANPSG 572
Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
G YD++K++ +N+ + P ++SRFDL FI +D + +D +A + LH
Sbjct: 573 GHYDKSKTVSENLKMKPALLSRFDLVFIQLDRPNAHLDNLLAAHVQRLH 621
Score = 44.4 bits (100), Expect = 0.012
Identities = 32/79 (40%), Positives = 41/79 (51%), Gaps = 7/79 (8%)
Query: 157 TIPTICRNPVCANRRRFMLDADKSVFVD---FQKIRIQETQ--AELPRGCIPRSLEVILR 211
T+PT CR C R F + SVF FQ +R+QE+ A G +PRS+EV L
Sbjct: 280 TLPTSCREG-CKARSNF-IPLRSSVFTRTEAFQTVRLQESMLGARSGHGQVPRSIEVELT 337
Query: 212 AEAVESVQAGDRYDFTGTL 230
E V++V GD TG L
Sbjct: 338 HELVDAVCPGDDVTITGIL 356
Score = 42.7 bits (96), Expect = 0.037
Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Query: 556 RYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAK 614
+YIA+AR + P +TE A + +Y +T RQLE++VRL + A+
Sbjct: 677 KYIAYARKNIHPKLTEAAALEIRNFYAEMRRAQQGMDSIP--VTTRQLEALVRLTQARAR 734
Query: 615 MHCSGHVTPAHVHEAYRLLNKSIIRVEQPDI 645
M T H + +L S+I V D+
Sbjct: 735 MDLESEATLQHAQDVIAILRYSMIDVFSNDV 765
>UniRef50_Q7R0Y4 Cluster: GLP_25_42162_38935; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_25_42162_38935 - Giardia lamblia
ATCC 50803
Length = 1075
Score = 197 bits (480), Expect = 1e-48
Identities = 97/213 (45%), Positives = 144/213 (67%), Gaps = 6/213 (2%)
Query: 333 ITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTT------LRGDINVCIVGDPSTAKSQ 386
+ ++ PSIHG VK+ +L+ L GG++ G+ RGD+++ I+GDP +KSQ
Sbjct: 544 LKAIAPSIHGMQVVKQAILMALVGGISHALDGGSGQAASRFTRGDLHMLILGDPGVSKSQ 603
Query: 387 LLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDK 446
LLK V I+P+ VYTSGK SSAAGLT +V + + +F ++AGAL+LA+ G+C IDE DK
Sbjct: 604 LLKYVQHISPKCVYTSGKGSSAAGLTVSVKKSSVTGEFYLQAGALVLANGGICIIDELDK 663
Query: 447 MDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSP 506
M+ D+ A+H+AMEQQT+S+AKAG+ +TL AR I+AAANP+ G+Y + + N+ +
Sbjct: 664 MNEIDRTALHQAMEQQTVSVAKAGIISTLEARAGIIAAANPVSGQYVSSLPVTCNLNIGD 723
Query: 507 PIMSRFDLFFILIDESSEMVDYAIARKIVDLHC 539
+MSRFDL ++ D + D A+++ IV HC
Sbjct: 724 ALMSRFDLICVVKDMVNYETDLAMSKFIVQQHC 756
Score = 41.5 bits (93), Expect = 0.086
Identities = 18/65 (27%), Positives = 34/65 (52%), Gaps = 1/65 (1%)
Query: 158 IPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVES 217
+P C N C + + + + + + DFQ+I +QE + G +P EV+L + ++
Sbjct: 412 LPKRCINETCRSSKLY-ISTSGTTYEDFQRITVQEPPNSVVSGQLPEKKEVLLTGDLIDK 470
Query: 218 VQAGD 222
V+ GD
Sbjct: 471 VKPGD 475
Score = 39.9 bits (89), Expect = 0.26
Identities = 25/81 (30%), Positives = 40/81 (49%), Gaps = 3/81 (3%)
Query: 554 LLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVA 613
L RYI +AR +P +T+E ++ ++Y IT RQ+ ++ RLAE A
Sbjct: 887 LTRYIFYARMMRPQLTKECQDIISKFYTNVRQMVTTGCT---PITNRQIGTLFRLAEAHA 943
Query: 614 KMHCSGHVTPAHVHEAYRLLN 634
++H VT + A RL +
Sbjct: 944 RLHLRKSVTKDDGNFAIRLFS 964
>UniRef50_UPI0000D557CF Cluster: PREDICTED: similar to
minichromosome maintenance protein domain containing 1;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
minichromosome maintenance protein domain containing 1 -
Tribolium castaneum
Length = 898
Score = 196 bits (478), Expect = 2e-48
Identities = 114/291 (39%), Positives = 176/291 (60%), Gaps = 15/291 (5%)
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE--GTTLRGDINVCIVGDPSTAKSQLLK 389
++ S+ P ++G VK V ++L GG ++ T G +R + ++ +VGDP T KSQLL+
Sbjct: 291 ILKSICPELYGLFIVKLAVAVVLAGGSSQHTKSDTGVRVRAEPHLLLVGDPGTGKSQLLR 350
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
S+I PR+V+T+G S+AAGLT V E+ ++ +E GAL+++D G+CCIDEF+ M
Sbjct: 351 FASKIIPRSVFTTGVGSTAAGLTVTAVM--ENGEWQLEGGALVMSDGGICCIDEFNTMKE 408
Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509
D+ +IHEAMEQQTIS+AKAG+ L+ R SILAA NP G D ++ L NVAL+ P++
Sbjct: 409 HDRTSIHEAMEQQTISVAKAGIVCKLSTRCSILAATNP-KGNLDASQPLHMNVALASPLL 467
Query: 510 SRFDLFFILIDE-----SSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSF 564
SRFDL ++ D+ S+M+DY + ES + ++ + L Y A +
Sbjct: 468 SRFDLILLIKDKVDDGWDSQMIDYIFTARENSNSSKLIESIN--WTIETLQAYFAIIKKN 525
Query: 565 KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKM 615
P++ ++A ++L YY R TVR L+S+VRL++G A++
Sbjct: 526 HPMLNDDAHRILSGYYQAQRRKNCRNKS---RTTVRLLDSLVRLSQGHARL 573
Score = 42.3 bits (95), Expect = 0.049
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Query: 157 TIPTICRNPV-CANRRRFML-DADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEA 214
T P C NP C L + D + D+Q++++QET +L GC+P S+ V L +
Sbjct: 154 TPPRQCTNPEGCKGTTIVNLGELDPTFCKDYQEVKMQETVNKLDIGCMPSSIWVTLEDDL 213
Query: 215 VESVQAGDRYDFTG 228
V+S + GD G
Sbjct: 214 VDSCKPGDNVTVCG 227
>UniRef50_Q7R0H3 Cluster: GLP_29_20689_22803; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_29_20689_22803 - Giardia lamblia
ATCC 50803
Length = 704
Score = 194 bits (472), Expect = 1e-47
Identities = 111/311 (35%), Positives = 172/311 (55%), Gaps = 17/311 (5%)
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391
LI S P IHG + K L L GG + + +RG+IN VGDP AKS LLK
Sbjct: 319 LIASFAPRIHGREDEKLACLCSLVGG-NEIVVPDMKVRGNINTLFVGDPGCAKSALLKFT 377
Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451
I R +Y +G+ +S AGLT A +R + D+ +E GAL++AD GVC +DE DK++ D
Sbjct: 378 CTIAERGIYVAGRGASGAGLTTAAIRIPGTTDYSLEGGALVIADQGVCALDELDKLEEAD 437
Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511
+ AI+E MEQ TIS+AKAG+ ATLNAR +++AAANP +D + S+ N+ + ++SR
Sbjct: 438 RTAIYEVMEQGTISVAKAGITATLNARATVVAAANPKFSIWDPSISVASNINIPEALISR 497
Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDC---------VYSRDDLLRYIAFAR 562
FD+ F++ D+ E D ++ + +LH + + Y + + +L YIA A+
Sbjct: 498 FDILFVIRDKIHEEEDMNLSLHVANLHKHAYDMYSAGVSDAQSTKILTEKELQAYIAVAK 557
Query: 563 SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVT 622
+ +P + + L++ Y IT R L + +R+++ +AK+ S V+
Sbjct: 558 NLRPAVPQH----LLDTYVMTYIQDRKEREF---ITPRALLATIRISQAIAKLRLSDSVS 610
Query: 623 PAHVHEAYRLL 633
V +A LL
Sbjct: 611 ADDVAKARDLL 621
Score = 47.2 bits (107), Expect = 0.002
Identities = 27/87 (31%), Positives = 47/87 (54%), Gaps = 4/87 (4%)
Query: 156 YTIPTICRNPVCANRRRF---MLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRA 212
Y+IP C + VC + + +L+ +SV IQE E+P G +PR++ V +R
Sbjct: 169 YSIPQRCDSEVCQQLKTYEAPVLNTKRSVINSLYIAIIQELPVEIPDGEVPRTMTVHIRK 228
Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGAL 239
E V +++ G++ GTL+ +P V +
Sbjct: 229 EGV-ALRPGEKVKLWGTLMPIPVVDTI 254
>UniRef50_Q9UYR7 Cluster: MCM inteins containing helicase,
minichromosome maintenance protein; n=2; Pyrococcus|Rep:
MCM inteins containing helicase, minichromosome
maintenance protein - Pyrococcus abyssi
Length = 1112
Score = 193 bits (471), Expect = 1e-47
Identities = 106/233 (45%), Positives = 149/233 (63%), Gaps = 4/233 (1%)
Query: 412 TAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGV 471
TAAVVRDE + +V+EAGAL+LAD G IDE DKM+ D+ IHEA+EQQTISL+KAG+
Sbjct: 794 TAAVVRDEFTGGWVLEAGALVLADGGYALIDELDKMNDKDRSVIHEALEQQTISLSKAGI 853
Query: 472 RATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIA 531
ATLNART+++AAANP GR++R K + + + L P +MSRFDL F+L+DE E +D IA
Sbjct: 854 TATLNARTTVIAAANPKQGRFNRMKRISEQINLPPTLMSRFDLIFVLVDEPDEKIDSEIA 913
Query: 532 RKIVDLHCNKEESYDCVYSRDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXX 590
R I+ + + E D L +YIA+AR + PVI+EEA + + +YY
Sbjct: 914 RHILRVRRGESEVVTPKIPHDLLRKYIAYARKNVHPVISEEAMEEIEKYYVKMRKSVKKS 973
Query: 591 XXXXWR---ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRV 640
+ IT RQLE+++RL+E A+M S VT EA +L+ ++ ++
Sbjct: 974 SEEEIKPIPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLRQI 1026
Score = 83.0 bits (196), Expect = 3e-14
Identities = 88/364 (24%), Positives = 169/364 (46%), Gaps = 43/364 (11%)
Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLK--PELSTLEVSFDDVEKYNQNLATTIIEEYYRIY 81
F FL E+ E+ E Y K+LL P+ S + +++ + ++ LA ++E
Sbjct: 10 FLRFLREYAEEGEEPLYIGKIKDLLAITPKRS-IAINWMHLNSFDPELAEEVLENPEECI 68
Query: 82 PFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIV 141
AI + L E M++D+ + F ++P V+E+ I LI++ G +
Sbjct: 69 LAAEDAIQ---IILKEDIMREDVP--RIHARFYNLPKTLMVKEIGAEHINKLIQVEGVVT 123
Query: 142 RTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVD-FQKIRIQETQAELPRG 200
R + P + F + C + + ++ + + V V +K + Q ++ +
Sbjct: 124 RVTEIKPFVSSAVF--VCKDCGHEMVVQQKPY----EGFVAVKKCEKCGSKNVQLDVEKS 177
Query: 201 CIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQM 260
+ ++ + E+++ G F I++ D+ +MPG R + ++ E +
Sbjct: 178 KFV-NFQMFRIQDRPETLKGGQMPRFIDG-ILLDDIVDTAMPGDRVVVVGILRVVQE-KR 234
Query: 261 EGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVY 320
E + K V E++Y ++ VS+ E+ T +E K+
Sbjct: 235 EKVPTFKK--VIEVNY--------IEPVSKEIEELEI--------------TPEEEQKIR 270
Query: 321 EMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDP 380
E+++ +++ + ++ S+ P+I+G EVK+G+ L LFGGV +T +GT LRGDI+V +VGDP
Sbjct: 271 ELAKRKDIVDAIVDSIAPAIYGYREVKKGIALALFGGVPRTLPDGTRLRGDIHVLLVGDP 330
Query: 381 STAK 384
AK
Sbjct: 331 GVAK 334
Score = 44.4 bits (100), Expect = 0.012
Identities = 19/30 (63%), Positives = 25/30 (83%)
Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGLTAA 414
SQLL+ ++ + PRA+YTSGK+SSAAGL A
Sbjct: 499 SQLLRYIANLAPRAIYTSGKSSSAAGLCVA 528
>UniRef50_A3B4V6 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 697
Score = 192 bits (469), Expect = 2e-47
Identities = 89/165 (53%), Positives = 124/165 (75%), Gaps = 1/165 (0%)
Query: 376 IVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLAD 435
I+GDP KSQLL+ + ++PR +Y G ++ AGLT AVV+D S D+ EAGA++LAD
Sbjct: 297 ILGDPGLGKSQLLQAAAAVSPRGIYVCGNTTTNAGLTVAVVKDSMSNDYAFEAGAMVLAD 356
Query: 436 NGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRA 495
G+CCIDEFDKM Q A+ EAMEQQ +S+AKAG+ A+L+ARTS+LAAANP+GG YDRA
Sbjct: 357 RGICCIDEFDKMSAEHQ-ALLEAMEQQCVSVAKAGLVASLSARTSVLAAANPVGGHYDRA 415
Query: 496 KSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCN 540
K++ +N+ +S ++SRFDL FIL+D+ E++D ++ I+ LH N
Sbjct: 416 KTVNENLKMSAALLSRFDLVFILLDKPDELLDKRVSDHIIALHSN 460
Score = 52.4 bits (120), Expect = 5e-05
Identities = 26/71 (36%), Positives = 43/71 (60%), Gaps = 2/71 (2%)
Query: 313 DKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE--GTTLRG 370
D E+ ++ +++ ++ S PSI+G+ VK G+ L LFGGV K +I+ +RG
Sbjct: 200 DLEFISKFKEEHGADVFRQILHSFCPSIYGHELVKAGITLALFGGVQKHSIDQNKVPVRG 259
Query: 371 DINVCIVGDPS 381
DI+ +VG+PS
Sbjct: 260 DIHAVVVGNPS 270
Score = 37.5 bits (83), Expect = 1.4
Identities = 32/104 (30%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSF-KPVIT--EEAGKLLVEYYXXXXXXXXXXXXX 593
LH K++ + C L +YI++ARS P I+ A L ++Y
Sbjct: 496 LHPEKDKDF-CPLPGPLLRKYISYARSHVNPRISMPSPAADSLQKFYLDLRKQSDSADGT 554
Query: 594 XWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
IT RQLES+VRLAE A++ VT E ++ +S+
Sbjct: 555 P--ITARQLESLVRLAEARARVDLREEVTLEDAKEVIDIMTESL 596
>UniRef50_Q019K0 Cluster: DNA replication licensing factor, MCM5
component; n=3; Ostreococcus|Rep: DNA replication
licensing factor, MCM5 component - Ostreococcus tauri
Length = 2370
Score = 191 bits (466), Expect = 5e-47
Identities = 89/207 (42%), Positives = 134/207 (64%), Gaps = 2/207 (0%)
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391
++ ++ P + G K ++L L GGV + G +RG+ ++ ++GDP KSQLLK
Sbjct: 1924 ILRAMCPQLFGMAMPKLALMLALIGGVPRRDSSGGRVRGESHILLIGDPGMGKSQLLKYA 1983
Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451
+ + PRA+ T+G SS+AGLT A + ES ++ +EAGAL+LAD GVCCIDEFD + +
Sbjct: 1984 AAVAPRAILTTGMGSSSAGLTVAATK--ESGEWALEAGALVLADGGVCCIDEFDSIREAE 2041
Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511
+ IHEAMEQQT+S+AKAG+ TL RT+++ A NP GG++D S+ N L+PP++SR
Sbjct: 2042 RATIHEAMEQQTLSVAKAGMVTTLRTRTTVIGATNPKGGQFDMGSSVAVNTGLAPPLLSR 2101
Query: 512 FDLFFILIDESSEMVDYAIARKIVDLH 538
FD +L D+ D ++ I++ H
Sbjct: 2102 FDCLIVLRDDRKPSWDREVSAHILESH 2128
Score = 36.7 bits (81), Expect = 2.4
Identities = 22/63 (34%), Positives = 33/63 (52%), Gaps = 4/63 (6%)
Query: 554 LLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612
L YIA +S +P +T+EA +LL YY R T+R LES++RL +
Sbjct: 2218 LRSYIAHVKSTLQPQLTKEAERLLTAYYQAQRRLEGRSVA---RTTIRMLESLIRLTQAH 2274
Query: 613 AKM 615
A++
Sbjct: 2275 ARL 2277
>UniRef50_Q16ZI3 Cluster: DNA replication licensing factor MCM1;
n=1; Aedes aegypti|Rep: DNA replication licensing factor
MCM1 - Aedes aegypti (Yellowfever mosquito)
Length = 1111
Score = 191 bits (466), Expect = 5e-47
Identities = 119/331 (35%), Positives = 180/331 (54%), Gaps = 14/331 (4%)
Query: 315 EWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINV 374
EW + + + L+ S P IHG VK V L L + G ++RG ++
Sbjct: 279 EWQNTIKEIGELAARDMLVQSFCPEIHGMYPVKLAVALSLASCTERFLGSGASVRGHSHL 338
Query: 375 CIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLA 434
+VGDP AKS+LLK SE++ R+V+T+G SAAGLTAA V+++ + +EAGAL+LA
Sbjct: 339 LLVGDPGLAKSRLLKFASEVSVRSVFTTGMGCSAAGLTAAAVKEDGEWQ--LEAGALVLA 396
Query: 435 DNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP--IGGRY 492
D GVCCIDEF+ M D+ +IHEAMEQQTIS+AKAG+ L+ R +LAA NP +
Sbjct: 397 DGGVCCIDEFNLMRESDKASIHEAMEQQTISMAKAGLVCKLSTRCVVLAATNPKNLLSMV 456
Query: 493 DRAKSLQQNVALSPPIMSRFDLFFILIDESSE-----MVDYAIARKIVDLHCNK--EESY 545
+ + ++ + P++SRFDL IL D+ +E + ++ +A +VD +K E +
Sbjct: 457 EMEANSSASLGIGGPLLSRFDLVLILTDDRNEHWDERVANHILALSVVDETRDKFEETTP 516
Query: 546 DCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESM 605
D + + L + + P IT++A +L YY R TVR L+S+
Sbjct: 517 DGHWDLERLQTHFLAIKDIHPRITDDANTILGAYYKLCRSDPSRDPS---RTTVRLLDSL 573
Query: 606 VRLAEGVAKMHCSGHVTPAHVHEAYRLLNKS 636
VRL++ A++ V P RL+ +
Sbjct: 574 VRLSQAHARLLFRDEVNPVDAITVIRLMEST 604
>UniRef50_Q4UAM8 Cluster: Cell division control protein, putative;
n=2; Theileria|Rep: Cell division control protein,
putative - Theileria annulata
Length = 916
Score = 191 bits (465), Expect = 7e-47
Identities = 105/276 (38%), Positives = 169/276 (61%), Gaps = 16/276 (5%)
Query: 295 AELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLML 354
A PT L +D + ++ E+SR+ +Y L+ S PSI N VK G+L L
Sbjct: 408 ANQPTKGLKYLGNENDFSDLQVYRILELSRNPMIYRILLDSFAPSIKARNNVKIGLLCQL 467
Query: 355 FGGVAKTTIEGTT---------LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKA 405
F A ++ + RG INV + GDP TAKSQLL ++PR++YTSGK+
Sbjct: 468 FSSNANSSDTNKSPDACYKVDNFRGIINVLLCGDPGTAKSQLLHYTHLLSPRSIYTSGKS 527
Query: 406 SSAAGLTAAVVRDE-ESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTI 464
SS+ GLTA++ +E ++ +I+ GA++LA+ GVCCIDE DK +++++E MEQQT+
Sbjct: 528 SSSVGLTASIKFNESDNGRAMIQPGAVVLANGGVCCIDELDKCHNESRLSLYEVMEQQTV 587
Query: 465 SLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILID---- 520
++AKAG+ ATL A T+ILA+ NPI RY++ K++ +N+ +SP + +RFDL ++++D
Sbjct: 588 TIAKAGIVATLKAETAILASCNPINSRYNKNKAVIENINISPSLFTRFDLIYLVLDHIDQ 647
Query: 521 ESSEMVDYAIARKIVDLH-CNKEESYDCVYSRDDLL 555
++ +++ +IAR + H +S+D Y R + +
Sbjct: 648 DTDQLISLSIARDFLLPHMTGASDSFD-TYDRSNTM 682
>UniRef50_Q495R6 Cluster: MCM8 protein; n=13; Eumetazoa|Rep: MCM8
protein - Homo sapiens (Human)
Length = 880
Score = 190 bits (462), Expect = 2e-46
Identities = 93/201 (46%), Positives = 134/201 (66%), Gaps = 3/201 (1%)
Query: 346 VKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSG 403
VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ + PR VY G
Sbjct: 460 VKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCG 519
Query: 404 KASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQT 463
++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Q A+ EAMEQQ+
Sbjct: 520 NTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQS 578
Query: 464 ISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESS 523
ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++SRFDL FIL+D +
Sbjct: 579 ISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLAFILLDTPN 638
Query: 524 EMVDYAIARKIVDLHCNKEES 544
E D+ ++ ++ + K+ +
Sbjct: 639 EHHDHLLSEHVIAIRAGKQRT 659
Score = 46.8 bits (106), Expect = 0.002
Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 3/80 (3%)
Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212
Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L
Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317
Query: 213 EAVESVQAGDRYDFTGTLIV 232
+ V+S GD TG + V
Sbjct: 318 DLVDSCVPGDTVTITGIVKV 337
Score = 39.1 bits (87), Expect = 0.46
Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%)
Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612
L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E
Sbjct: 706 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 763
Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638
A++ T + ++ S++
Sbjct: 764 ARLELREEATKEDAEDIVEIMKYSML 789
>UniRef50_Q3IML4 Cluster: ATP-dependent DNA helicase; n=1;
Natronomonas pharaonis DSM 2160|Rep: ATP-dependent DNA
helicase - Natronomonas pharaonis (strain DSM 2160 /
ATCC 35678)
Length = 1037
Score = 190 bits (462), Expect = 2e-46
Identities = 128/318 (40%), Positives = 183/318 (57%), Gaps = 36/318 (11%)
Query: 379 DPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE--ESFDFVIEAGALMLADN 436
D + SQLL+ V I PR+VYTSGK SS+AGLTAA VRD+ E + +EAGAL+LAD
Sbjct: 665 DVVSHNSQLLQYVKNIAPRSVYTSGKGSSSAGLTAAAVRDDFGEGQQWTLEAGALVLADQ 724
Query: 437 GVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAK 496
G+ +DE DKM DQ A+H+A+EQQ IS++KAG+ ATL +R S+LAAANPI GR+D +
Sbjct: 725 GIAAVDELDKMRSEDQSAMHQALEQQEISVSKAGINATLKSRCSLLAAANPIHGRFDEYE 784
Query: 497 SLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVD--------LHCNK------- 541
+ + L PP++SRFDL F + D+ E D +A I++ H K
Sbjct: 785 PFAEQIDLDPPLISRFDLIFTVTDQPDEEEDRQLAEHIIETNYAGELQTHRTKAATSNVS 844
Query: 542 EESYDCVYS------RDDLLR-YIAFA-RSFKPVITEEAGKLLVEYYXXXXXXXXXXXXX 593
+E D V D+LLR Y+A+A R+ P +TEEA + + E+Y
Sbjct: 845 QEQVDSVTEDVAPAIDDELLRKYVAYAKRNCYPTMTEEAKEAIQEFYVDLRLEGQSEDNP 904
Query: 594 XWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQ 653
IT R+LE++VRLAE A++ S T +A R++ I+R D+ +D + +
Sbjct: 905 V-PITARKLEALVRLAEASARIRLSDTATK---DDAERVI--EIVRSSLEDVGVDPETGE 958
Query: 654 CEPSMDVDQDEPNGTAET 671
+D D E +GT++T
Sbjct: 959 ----LDADIIE-SGTSKT 971
Score = 70.9 bits (166), Expect = 1e-10
Identities = 29/80 (36%), Positives = 52/80 (65%), Gaps = 2/80 (2%)
Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364
EDM +TD++ ++ E+S D +Y ++ S+ PSI+G + K +++ LF GV K +
Sbjct: 254 EDM--DITDEDKQRIIELSNDDGIYQQMVESMAPSIYGYEQQKLAIIMQLFSGVTKDLPD 311
Query: 365 GTTLRGDINVCIVGDPSTAK 384
G+ +RGD+++ ++GDP T K
Sbjct: 312 GSRIRGDLHMLLIGDPGTGK 331
Score = 57.2 bits (132), Expect = 2e-06
Identities = 46/192 (23%), Positives = 88/192 (45%), Gaps = 22/192 (11%)
Query: 54 TLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSF 113
+L + +DD+ +++ +LA ++ + +I + A+ Y L + D+Q +V
Sbjct: 38 SLYIDWDDLYRFDADLADDLVAQPDQIRDYAEEALRLYDLPV-------DVQLGRAHVRV 90
Query: 114 VDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF--YTIPTICRNPV----- 166
++ +R++ G L+ ++G + + V P++ + F T+ R P
Sbjct: 91 HNLQQTTGIRDIRARHRGNLVEVTGIVRKATDVRPKITEAAFECQRCGTLTRIPQTAGDF 150
Query: 167 --------CANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESV 218
C + F ++ D+S FVD QKIR+QE+ L G P+S++V + + V
Sbjct: 151 HDPHECQGCERQGPFDINFDQSEFVDAQKIRVQESPEGLRGGETPQSIDVHIEDDITGKV 210
Query: 219 QAGDRYDFTGTL 230
AGD G L
Sbjct: 211 TAGDHVRVAGVL 222
>UniRef50_Q54MD0 Cluster: MCM family protein; n=1; Dictyostelium
discoideum AX4|Rep: MCM family protein - Dictyostelium
discoideum AX4
Length = 1275
Score = 184 bits (448), Expect = 8e-45
Identities = 119/338 (35%), Positives = 193/338 (57%), Gaps = 35/338 (10%)
Query: 304 TEDMRKQMTDKEWDKVYEMSRDRN---LYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAK 360
T+++R+Q ++ W + D+N N ++ + ++G VK +LL+L GG
Sbjct: 308 TDEIRRQF-EEFW-----LQHDKNPLLARNRILKQVCSGVYGLFVVKLALLLILIGGCNI 361
Query: 361 TTIE-GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE 419
E G RG+ ++ +VG+P T KSQ LK +++ R+V T+G ++ AGLTAA V++
Sbjct: 362 DDAETGAKKRGECHLLLVGEPGTGKSQFLKFAAKLAQRSVLTTGIGTTTAGLTAASVKEP 421
Query: 420 ESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNART 479
S + V+EAGAL+LAD GVCCIDEF + D+ IHEAMEQQ++S+AK GV + L+ RT
Sbjct: 422 GSGETVLEAGALVLADGGVCCIDEFSGIKTKDRATIHEAMEQQSLSIAKGGVISRLHTRT 481
Query: 480 SILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDES----SEMVDYAIARKIV 535
SI+AA N GRYD ++L N +L+ P++SRFD+ +L D E V I R+ +
Sbjct: 482 SIIAATN-AKGRYDPNETLTVNTSLATPLLSRFDIIILLTDNQDPNWDEQVSEFILRQAM 540
Query: 536 ---------DLHCNKEES--------YDCVYSRDDLLRYIAFAR-SFKPVITEEAGKLLV 577
+L+ N ++ +D ++ + L YI + + SF+P +T+ + +L+
Sbjct: 541 ICGGGGGGNNLNYNGQQQSGTVNNDFHDDFWNLEMLQSYIYYVKGSFRPQLTDASKRLID 600
Query: 578 EYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKM 615
EY+ R T+R LES++RL++ A++
Sbjct: 601 EYFRKQRSSVAKANES--RTTIRLLESLIRLSQAHARL 636
Score = 48.8 bits (111), Expect = 6e-04
Identities = 28/78 (35%), Positives = 42/78 (53%), Gaps = 2/78 (2%)
Query: 156 YTIPTICRNPV--CANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAE 213
Y++P C NP CAN F D+Q+I++QE +L G IP S+ V+L+ +
Sbjct: 195 YSVPKKCPNPDINCANSYNFKPLEAVGEHCDYQEIKLQEQIHQLGAGSIPGSIIVLLQED 254
Query: 214 AVESVQAGDRYDFTGTLI 231
V+ QAGD +G +I
Sbjct: 255 LVDQCQAGDDIIVSGIVI 272
>UniRef50_Q235L3 Cluster: MCM2/3/5 family protein; n=1; Tetrahymena
thermophila SB210|Rep: MCM2/3/5 family protein -
Tetrahymena thermophila SB210
Length = 797
Score = 183 bits (446), Expect = 1e-44
Identities = 119/364 (32%), Positives = 193/364 (53%), Gaps = 33/364 (9%)
Query: 302 LTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT 361
L ED ++ ++++ +S D ++ L+ S+ P+I G+ VK G+LL + GG
Sbjct: 331 LLNED-EEEFSEEDIIMAQTLSDDPRVFPRLVKSVCPTIFGHELVKAGLLLSILGGAPVN 389
Query: 362 TIEGTT----------LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGL 411
++G + R D +V ++GDP KSQLLK ++ IT R++YT G +SS AGL
Sbjct: 390 ELQGISNPFADDNKISFRSDCHVLLIGDPGLGKSQLLKFLANITTRSIYTCGSSSSNAGL 449
Query: 412 TAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGV 471
T V +D + + +EAGAL+L+D GVCCIDEFDKM D + EAMEQQT+SLAK+GV
Sbjct: 450 TVTVTKDPVTGESTLEAGALILSDQGVCCIDEFDKMS-ADHYVLLEAMEQQTVSLAKSGV 508
Query: 472 RATLNARTSILAAANPIGGRYD--------------RAKSLQQNVALSPPIMSRFDLFFI 517
+L +R +I+A+ANP G Y R + L +++ + D
Sbjct: 509 LCSLQSRATIIASANPKEGHYKFDLIFLLLDTPDPMRDQKLSEHIMKLHSRKRKKDEMGQ 568
Query: 518 LIDESSEMV---DYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSF-KPVITEEAG 573
+ + + + +Y+ + + C E + + + S + +YI + + F +PV++ EA
Sbjct: 569 FVQKQPQYMQDTEYSSLTEKLQAEC-AEVTENLILSPAIMRKYIQYVKKFVQPVLSREAA 627
Query: 574 KLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
+++ E+Y IT RQLES+VRL++ AK+ C VT E L+
Sbjct: 628 EIIKEFYLTLRESHFNTSSIP--ITNRQLESLVRLSQARAKIECRDIVTKKDALEVVELM 685
Query: 634 NKSI 637
+S+
Sbjct: 686 QESL 689
>UniRef50_Q5JGW1 Cluster: DNA replication licensing factor, MCM2/3/5
family; n=1; Thermococcus kodakarensis KOD1|Rep: DNA
replication licensing factor, MCM2/3/5 family -
Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
Length = 810
Score = 183 bits (446), Expect = 1e-44
Identities = 111/333 (33%), Positives = 180/333 (54%), Gaps = 17/333 (5%)
Query: 309 KQMTDKEWDKVYEMSRDRN--LYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGT 366
+++++++ +V E++R L + +S+ P+++G K G + + GGV
Sbjct: 400 EELSEEDLRRVRELARVHGDKLPFVVASSIAPNLYGLEREKLGAAVSIVGGVPTQAKP-- 457
Query: 367 TLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESF-DFV 425
RG I++ +VGDP K++LL V + P+A++TSG SS GLTA V R+E S D++
Sbjct: 458 --RGHIHLLLVGDPGCGKTELLGAVERVAPKAIFTSGPGSSGVGLTATVKRNEVSKGDWM 515
Query: 426 IEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAA 485
I GAL+LA GVC IDE +KM ++ A+H AMEQQ I + KAG+ L T+I+A A
Sbjct: 516 IVGGALVLASGGVCLIDELEKMKEDERKALHTAMEQQLIPINKAGINVVLKIDTTIMATA 575
Query: 486 NPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESY 545
NP GG++DR K++ + + P +++RFDL F+++D DY ++D ++
Sbjct: 576 NPKGGKFDRDKTVIEQIDFPPTLLNRFDLAFVVLD------DYQEGDDVLDYVMEVNDAG 629
Query: 546 DCVYSRDDLLR-YIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLES 604
+DLLR + +ARS +P +EEA + + + + +R
Sbjct: 630 AAGPIPEDLLRKFFVYARSLRPRFSEEAKEAIKAGFKELRKKYKSGKIA---LNLRYFNG 686
Query: 605 MVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
++R+AE AK+ S V P V A L SI
Sbjct: 687 LMRIAEAFAKLRLSETVEPVDVERAVNLFESSI 719
>UniRef50_Q2GYD6 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 850
Score = 182 bits (444), Expect = 3e-44
Identities = 90/168 (53%), Positives = 118/168 (70%)
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGA 430
DINV ++GDP TAKSQ+LK V + RAV+ +G+ +SA GLTA+V RD + ++ +E GA
Sbjct: 503 DINVLLLGDPGTAKSQVLKYVEKTAHRAVFATGQGASAVGLTASVRRDPLTSEWTLEGGA 562
Query: 431 LMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGG 490
L+LAD G C IDEFDKM+ D+ +IHEAMEQQTIS++KAG+ TL AR I+AAANPIGG
Sbjct: 563 LVLADKGTCLIDEFDKMNDQDRTSIHEAMEQQTISISKAGIVTTLQARCGIIAAANPIGG 622
Query: 491 RYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
RY+ NV L+ PI+SRFD+ ++ D D +AR IV H
Sbjct: 623 RYNSTIPFSANVELTEPILSRFDILCVVRDTVEPEEDERLARFIVGSH 670
Score = 67.3 bits (157), Expect = 2e-09
Identities = 57/246 (23%), Positives = 113/246 (45%), Gaps = 24/246 (9%)
Query: 2 DVADTYATQSQVKDEVGIRCQKLFQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFD 60
DV + T + V ++ F+ FL E+ +D+ Y + L + +LEVS++
Sbjct: 194 DVKASSLTDWVAQPAVQRTIKREFKAFLTEYTDDSGSSVYGNRIRTLGEINAESLEVSYE 253
Query: 61 DVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRH 120
+ LA + + ++ ++ +L L ++ E +V D+P +
Sbjct: 254 HLSTSKAILAYFLANAPAAMLKLFDQVAMDVVL-LHYPDYERI--HSEIHVRIFDLPVHY 310
Query: 121 KVRELTTAKIGTLIRISGQIVRTHPVHPEL------------VQGTFYTIPTI------C 162
+R+L + + L+R+SG + R V P+L G F + C
Sbjct: 311 TLRQLRQSHLNCLVRVSGVVTRRSGVFPQLKYVKFDCGKCGITLGPFQQESNVEVKISYC 370
Query: 163 RNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGD 222
++ C +R F L+++K+V+ ++QK+ +QE+ +P G +PR EVIL + ++ + G+
Sbjct: 371 QS--CQSRGPFSLNSEKTVYRNYQKLTLQESPGTVPAGRLPRHREVILLWDLIDKAKPGE 428
Query: 223 RYDFTG 228
+ TG
Sbjct: 429 EIEVTG 434
>UniRef50_UPI00015B5C8D Cluster: PREDICTED: similar to
mini-chromosome maintenance deficient 9; n=1; Nasonia
vitripennis|Rep: PREDICTED: similar to mini-chromosome
maintenance deficient 9 - Nasonia vitripennis
Length = 655
Score = 182 bits (443), Expect = 3e-44
Identities = 87/206 (42%), Positives = 136/206 (66%), Gaps = 4/206 (1%)
Query: 330 NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLK 389
+N++ S+ P ++G +K + ++L GGV KT GT +RGD ++ + GDP T KSQ+L+
Sbjct: 273 DNILASICPQLYGMYSMKLALAVILCGGVTKTIKTGTRVRGDPHLLLCGDPGTGKSQMLR 332
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
+ + R++ T+G ++AAGLTAA ++D + + +EAGAL+ A+ GVCCIDE M
Sbjct: 333 TAARLAARSIMTTGVGTTAAGLTAAAIKDSDGWH--LEAGALVSANGGVCCIDELTTMST 390
Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509
D +IHEAMEQQTIS+AKAG+ +TLN+R +++AA NP+GGR+ + ++ + L P++
Sbjct: 391 SDMASIHEAMEQQTISIAKAGLVSTLNSRCTVVAAINPVGGRFTDGEEVK--MRLGGPLL 448
Query: 510 SRFDLFFILIDESSEMVDYAIARKIV 535
SRFDL L D D ++ I+
Sbjct: 449 SRFDLILFLRDRHDPQWDELVSNHIL 474
Score = 39.9 bits (89), Expect = 0.26
Identities = 25/70 (35%), Positives = 36/70 (51%), Gaps = 3/70 (4%)
Query: 546 DCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESM 605
D ++ L Y A + KPV+T++A K+L Y R TVR ++S+
Sbjct: 530 DGLWDEKTLREYFAHVHTMKPVMTKDAEKVLRATYFYHRHRPERREE---RTTVRLMDSL 586
Query: 606 VRLAEGVAKM 615
VRLAEG AK+
Sbjct: 587 VRLAEGHAKL 596
>UniRef50_Q8TWR7 Cluster: Predicted ATPase involved in replication
control, Cdc46/Mcm family; n=1; Methanopyrus
kandleri|Rep: Predicted ATPase involved in replication
control, Cdc46/Mcm family - Methanopyrus kandleri
Length = 656
Score = 181 bits (441), Expect = 6e-44
Identities = 125/357 (35%), Positives = 193/357 (54%), Gaps = 22/357 (6%)
Query: 302 LTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT 361
L ED+R T E ++ E++ L + ++ P IHG+ +K+ V L LF +
Sbjct: 240 LPEEDLR--FTQDEVERFEELAEGDPL-GEFVEAVAPHIHGHEVIKKAVSLQLF-----S 291
Query: 362 TIEGTTLRGDINVCIVGDPSTAKSQLLKQVSE-ITPRAVYTSGKASSAAGLTAAVVRDEE 420
+E +R ++V IVGDP+TAKSQ+L+ V E + PR VY S + + AGLTAA R E+
Sbjct: 292 CVEEGQIRERVHVLIVGDPATAKSQILQHVIEHLAPRGVYVSAQHVTGAGLTAAAERTED 351
Query: 421 SFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTS 480
+ +EAGA+++AD GV IDE DK GD A+ EAME IS+AKAG+ TLNAR +
Sbjct: 352 GW--TLEAGAVVMADGGVIAIDELDKASRGDLNALLEAMESGKISVAKAGITTTLNARCA 409
Query: 481 ILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCN 540
+LAAANP GR+ +++ + L P ++SRFD+ DE D +A ++++
Sbjct: 410 VLAAANPEAGRWQGGHPIEE-INLDPALLSRFDVILFTRDEPDPEQDKLVAERMMEAF-- 466
Query: 541 KEESYDCVYSRDDLL-RYIAFARSFKP--VITEEAGKLLVEYYXXXXXXXX----XXXXX 593
+ +D + + +LL RY+ +A P I+E+A + L +++
Sbjct: 467 -DGEFDEIEGKYELLRRYVLYATKEFPNVTISEDAREELRDWFVSARQEAADRIDEGDLR 525
Query: 594 XWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDED 650
+T RQ+ S++RLA A+M S V V A ++ + + V Q D LD D
Sbjct: 526 TVPVTRRQMGSVLRLARASARMRLSETVGRGDVSVALSVVEEFMKEVMQEDGVLDAD 582
Score = 36.3 bits (80), Expect = 3.2
Identities = 35/140 (25%), Positives = 60/140 (42%), Gaps = 14/140 (10%)
Query: 100 MKKDLQDKE-CYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTI 158
+KK+ D + +V F P R + R+++ L+ + G + R V E+V+
Sbjct: 69 IKKERPDVDRVWVEFRGSPIRLRARDMSVEFKDRLVTVEGIVRRVDNVAAEVVR-VEAEC 127
Query: 159 PTICRNPVCANRRRFMLDA-----------DKSVFVDFQKIRIQETQAELPRGCIPRSLE 207
P C N RR + D D+ + D+Q + +QE + G P ++E
Sbjct: 128 PQ-CGNRFEVRRREYRPDVRCPNCGMRCEPDELFYTDYQLVVLQEAPEHVRGGEQPATVE 186
Query: 208 VILRAEAVESVQAGDRYDFT 227
V R + + V+ GDR T
Sbjct: 187 VEFRYDHINRVRPGDRVRVT 206
>UniRef50_Q8U3I4 Cluster: Cell division control protein 21; n=1;
Pyrococcus furiosus|Rep: Cell division control protein
21 - Pyrococcus furiosus
Length = 1049
Score = 181 bits (440), Expect = 8e-44
Identities = 101/235 (42%), Positives = 146/235 (62%), Gaps = 6/235 (2%)
Query: 412 TAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGV 471
TAA VRDE + +V+EAGAL+LAD G IDE DKM D+ IHEA+EQQTIS++KAG+
Sbjct: 729 TAAAVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGI 788
Query: 472 RATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIA 531
ATLNART+++AAANP GR++R K+ + + L P ++SRFDL F+LIDE + +D +A
Sbjct: 789 TATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVA 848
Query: 532 RKIVDLHCNKEESYDCVYSRDDLLRYIAFAR-SFKPVITEEAGKLLVEYYXXXXXXXXXX 590
R I+ + + E + L +YIA+AR + PVI+EEA + + +YY
Sbjct: 849 RHILRVRRGESEVVAPKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKT 908
Query: 591 XXXX-----WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRV 640
IT RQLE+++RL+E A+M S VT EA +L+ ++ ++
Sbjct: 909 KGEEEGIPPIPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQI 963
Score = 111 bits (267), Expect = 7e-23
Identities = 50/113 (44%), Positives = 82/113 (72%)
Query: 302 LTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT 361
++ E +++ +E + E+++ +++ + ++ S+ P+I+G EVK+G+ L LFGGV++
Sbjct: 252 VSKEIQELEISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRK 311
Query: 362 TIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAA 414
+GT LRGDI+V +VGDP AKSQ+L+ V+ + PRA+YTSGK+SSAAGL A
Sbjct: 312 LPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGKSSSAAGLCVA 364
Score = 52.8 bits (121), Expect = 3e-05
Identities = 58/228 (25%), Positives = 101/228 (44%), Gaps = 26/228 (11%)
Query: 25 FQDFLEEFK-EDNEIKYEKHAKELLK--PELSTLEVSFDDVEKYNQNLATTIIEEYYRIY 81
F +FL E+ ED Y +LL P+ S + + + + ++ LA +IE
Sbjct: 10 FANFLREYTDEDGNPVYRGKITDLLTITPKRS-VAIDWMHLNSFDSELAHEVIENPEEGI 68
Query: 82 PFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIV 141
AI + L E ++D+ + + F ++P V+++ I LI++ G +
Sbjct: 69 SAAEDAIQ---IVLREDFQREDVG--KIHARFYNLPETLMVKDIGAEHINKLIQVEGIVT 123
Query: 142 RTHPVHP--------------ELV--QGTFYTIPTICRNPVCANRRRFMLDADKSVFVDF 185
R + P E++ Q + ++ + + C ++ LD +KS FV+F
Sbjct: 124 RVGEIKPFVSVAVFVCKDCGHEMIVPQKPYESLEKVKKCEQCGSKN-IELDVNKSSFVNF 182
Query: 186 QKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVV 233
Q RIQ+ L G +PR ++ IL + V+ GDR TG L VV
Sbjct: 183 QSFRIQDRPETLKGGEMPRFIDGILLDDIVDVALPGDRVIVTGILRVV 230
>UniRef50_Q5UYX8 Cluster: Cell division control protein 21; n=1;
Haloarcula marismortui|Rep: Cell division control protein
21 - Haloarcula marismortui (Halobacterium marismortui)
Length = 1175
Score = 181 bits (440), Expect = 8e-44
Identities = 110/270 (40%), Positives = 159/270 (58%), Gaps = 26/270 (9%)
Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE--ESFDFVIEAGALMLADNGVCCID 442
SQ+L + I PR+VYTSGK SS+AGLTAA VRD+ + + +EAGAL+LAD G+ ID
Sbjct: 809 SQMLSYIENIAPRSVYTSGKGSSSAGLTAAAVRDDFGDGQQWTLEAGALVLADQGIAAID 868
Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502
E DKM P D+ A+HEA+EQQ IS++KAG+ ATL +R S+L AANP GR+D+ + + + +
Sbjct: 869 ELDKMSPEDRSAMHEALEQQRISVSKAGINATLKSRCSLLGAANPKYGRFDQYEPIGEQI 928
Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIV------DLHCNKEESYDCVYSRD---- 552
L P ++SRFDL F + D+ E D +A I+ +LH ++ E+ +S +
Sbjct: 929 DLEPALISRFDLIFTVTDKPDEEKDRNLAEHIIQTNYAGELHTHRTENPTSNFSEEEVGT 988
Query: 553 -----------DLLR-YIAFA-RSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITV 599
DLLR Y+A+A R+ P +TEEA + ++Y +T
Sbjct: 989 VTEEVAPTIEPDLLRKYVAYAKRNCFPTMTEEAKSRIEDFYVDLRLKGQDEDAPV-PVTA 1047
Query: 600 RQLESMVRLAEGVAKMHCSGHVTPAHVHEA 629
R+LE++VRLAE A++ S V A A
Sbjct: 1048 RKLEALVRLAEASARIRLSDTVDEADADRA 1077
Score = 66.9 bits (156), Expect = 2e-09
Identities = 28/80 (35%), Positives = 54/80 (67%), Gaps = 2/80 (2%)
Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364
EDM ++TD + ++ E+S + ++Y+ ++ ++ PSI+G + K ++L LF GV K +
Sbjct: 254 EDM--EITDADKTEIVELSSEPDIYDKMVGAIAPSIYGYEKEKLAMMLQLFSGVTKELPD 311
Query: 365 GTTLRGDINVCIVGDPSTAK 384
G+ +RGD+++ ++GDP T K
Sbjct: 312 GSRIRGDLHMLLIGDPGTGK 331
Score = 61.3 bits (142), Expect = 1e-07
Identities = 52/222 (23%), Positives = 99/222 (44%), Gaps = 25/222 (11%)
Query: 27 DFLEEFKEDNEIKYEKHAKELLKP---ELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83
+ ++ F+E Y EL + + +L + +DD+ +++ +LA + +I +
Sbjct: 8 ELIDRFEEFYRNYYRNEIGELAQKYPNDQKSLYIDWDDLYRFDPDLADDYRTKPEQIQEY 67
Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143
A+ Y L + D+ + +V ++P +R+L G L+ + G I +
Sbjct: 68 AEEALRLYDLPV-------DVSLGQAHVRVRNLPESEDIRDLRHEHHGNLVAVRGIIRKA 120
Query: 144 HPVHPELVQGTF--YTIPTICRNPV-------------CANRRRFMLDADKSVFVDFQKI 188
V P++++ F T+ R P C + F L+ D+S F+D QK+
Sbjct: 121 TDVRPKVIEAAFECQRCGTLTRIPQTAGDFQEPHDCQGCERQGPFRLNTDQSQFIDAQKL 180
Query: 189 RIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTL 230
R+QE+ L G P+S+++ + + V AGD TG L
Sbjct: 181 RVQESPEGLRGGETPQSIDINIEDDITGHVTAGDHVRVTGIL 222
>UniRef50_Q8SRK9 Cluster: DNA REPLICATION LICENSING FACTOR OF THE
MCM FAMILY; n=1; Encephalitozoon cuniculi|Rep: DNA
REPLICATION LICENSING FACTOR OF THE MCM FAMILY -
Encephalitozoon cuniculi
Length = 563
Score = 178 bits (433), Expect = 5e-43
Identities = 116/328 (35%), Positives = 175/328 (53%), Gaps = 19/328 (5%)
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391
L+ S I G VK G+LL L G + T R + ++ +VGD T KS LLK
Sbjct: 224 LVNSFAEEIQGLENVKLGLLLALVSGSHGADQKSGT-RSNSHILLVGDSGTGKSHLLKTC 282
Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451
S + AV T+G ++ AGLT VR + ++V+EAGAL+LAD G+CCIDEF+K+ +
Sbjct: 283 SRLLSPAVLTNGVGTTQAGLTTCAVR--QGREWVLEAGALVLADTGLCCIDEFNKLKVNE 340
Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511
+ + EAMEQQT+S+AKAG+ ++LN R S++AA N +Y KS+ +N+ ++ P++SR
Sbjct: 341 KNGLLEAMEQQTLSIAKAGIVSSLNTRCSVIAAIN-TRHKYSFNKSISENIMVATPLISR 399
Query: 512 FDLFFILIDESSEMVDYAIARKIVDLH-----CNKEESYDCVYSRDDLLRYIAFARSFKP 566
FDL F L D+ D I KI+ +K++ C + + L YI AR +
Sbjct: 400 FDLIFGLFDDRDGRSDLLIVDKILGRRPETGLTDKKQGSVC-WDHNILRNYIGVARKRRA 458
Query: 567 VITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHV 626
VI ++ +L+ YY TVR LES+ RL E +K+ S V
Sbjct: 459 VIPDDLNAVLLSYYHHRRKAEGANEFN----TVRMLESLARLTEAHSKLLNSERAEEGDV 514
Query: 627 HEAYRLL-----NKSIIRVEQPDIHLDE 649
+ A LL K ++ ++ + +DE
Sbjct: 515 YSAIILLETALGTKPLVEIDPCRVFVDE 542
>UniRef50_A0BKB5 Cluster: Chromosome undetermined scaffold_111,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_111,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 702
Score = 177 bits (431), Expect = 1e-42
Identities = 98/234 (41%), Positives = 142/234 (60%), Gaps = 10/234 (4%)
Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364
E + + T E V ++++ L+ LI + PSI+G+ VK G+LL L GG
Sbjct: 257 EQINESFTRHEIKTVNDLAKSGELFYALINNFCPSIYGHEIVKAGLLLSLVGG------- 309
Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDF 424
T R + +VGDP KSQLLK ++ R++Y SG A S GLT +V + ++ D
Sbjct: 310 STCNRNASHCLLVGDPGQGKSQLLKFAHLLSTRSIYVSGTAVSQCGLTCSV--NHKNDDT 367
Query: 425 VIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAA 484
+I+AGAL+LADNGVCC+DE DKM A+ EAMEQQTI+LAK+ V ART+I+A
Sbjct: 368 IIDAGALVLADNGVCCLDEIDKMQ-SQHYALLEAMEQQTITLAKSAVMCQFYARTTIIAT 426
Query: 485 ANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
ANP G +++ KSL +N+ + ++SRFDL ++LIDE D ++ I++ H
Sbjct: 427 ANPAQGHFNKTKSLIENLKIQNTLLSRFDLIYLLIDEPDMERDQKLSEHIMNFH 480
Score = 35.9 bits (79), Expect = 4.3
Identities = 25/81 (30%), Positives = 37/81 (45%), Gaps = 5/81 (6%)
Query: 556 RYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKM 615
+ IA ++ K V+T A KL+ YY IT RQLES++RL++ AK+
Sbjct: 524 KIIAHVKNIKSVLTLGAQKLIASYYLKIRQTAFGMP-----ITSRQLESLIRLSQAKAKL 578
Query: 616 HCSGHVTPAHVHEAYRLLNKS 636
VT A + +S
Sbjct: 579 CLRQEVTEEDAQFAIDIFEES 599
>UniRef50_Q9HNA5 Cluster: MCM / cell division control protein 21;
n=1; Halobacterium salinarum|Rep: MCM / cell division
control protein 21 - Halobacterium salinarium
(Halobacterium halobium)
Length = 831
Score = 177 bits (430), Expect = 1e-42
Identities = 109/262 (41%), Positives = 154/262 (58%), Gaps = 26/262 (9%)
Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE--ESFDFVIEAGALMLADNGVCCID 442
SQ++ V I PR+VYTSGK SSAAGLTAA VRD+ + + +EAGAL+LADNGV +D
Sbjct: 465 SQMISYVQNIAPRSVYTSGKGSSAAGLTAAAVRDDFGDGQQWSLEAGALVLADNGVAAVD 524
Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502
E DKM D+ A+HEA+EQQ IS++KAG+ ATL AR S+L AANP GR+D+ + + + +
Sbjct: 525 ELDKMADDDRSAMHEALEQQKISVSKAGINATLKARCSLLGAANPKYGRFDQYEPIGEQI 584
Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIV------DLHCNKEESYDCVYSRDD--- 553
L P ++SRFDL F + D+ D A+A I+ +L+ EE + YS +
Sbjct: 585 DLEPALISRFDLIFTVTDQPDPEEDAALADHILQTNYAGELNTQNEELANANYSEAEIES 644
Query: 554 -------------LLRYIAFA-RSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITV 599
L +YIA+A R+ P +T +A + + E+Y +T
Sbjct: 645 QTEDVAPAIEPGLLRKYIAYARRTCFPTMTPDARQAIEEFYVDLRSKGADEDAPV-PVTA 703
Query: 600 RQLESMVRLAEGVAKMHCSGHV 621
RQLE++VRLAE A++ S V
Sbjct: 704 RQLEAIVRLAEASARLRLSDSV 725
Score = 58.0 bits (134), Expect = 9e-07
Identities = 25/84 (29%), Positives = 49/84 (58%), Gaps = 2/84 (2%)
Query: 301 DLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAK 360
D +++ DKE ++ +S ++ ++ S+ P+I+G+ E K ++L LF GV K
Sbjct: 201 DAEFDELNISEADKE--EIVALSDHEEIHEEMVDSMAPAIYGHREAKLAMMLQLFSGVTK 258
Query: 361 TTIEGTTLRGDINVCIVGDPSTAK 384
+ + +RGD+++ ++GDP T K
Sbjct: 259 HLPDKSRIRGDLHMLLIGDPGTGK 282
Score = 52.0 bits (119), Expect = 6e-05
Identities = 27/64 (42%), Positives = 37/64 (57%)
Query: 167 CANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDF 226
C + F LD D+S FVD QK+RIQE+ L G P+S++V + +A +V GD
Sbjct: 111 CERQGPFKLDPDRSEFVDSQKLRIQESPEGLGGGETPQSIDVHVEDDATGNVTPGDHVTV 170
Query: 227 TGTL 230
TG L
Sbjct: 171 TGVL 174
>UniRef50_A3DNW1 Cluster: MCM family protein; n=1; Staphylothermus
marinus F1|Rep: MCM family protein - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 1047
Score = 174 bits (423), Expect = 9e-42
Identities = 79/154 (51%), Positives = 117/154 (75%)
Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369
++T ++ DK+ E++RD + +I S+ P+I+G+ +K + L+LFGGV K +GT +R
Sbjct: 277 EITREDEDKIKELARDPWIREKIIASIAPAIYGHWNIKEAIALLLFGGVPKLLPDGTRIR 336
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
GDI++ +VGDP TAKSQ+L+ ++I PR +YTSGK S+AAGLTA+V+RD+ + ++ +EAG
Sbjct: 337 GDIHILLVGDPGTAKSQMLQYTAKIAPRGIYTSGKGSTAAGLTASVLRDKATGEYYLEAG 396
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQT 463
AL+LAD GV CIDE DKM D+ AIHEA+EQQ+
Sbjct: 397 ALVLADGGVACIDEIDKMREEDRSAIHEALEQQS 430
Score = 124 bits (298), Expect = 1e-26
Identities = 71/182 (39%), Positives = 108/182 (59%), Gaps = 5/182 (2%)
Query: 463 TISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDES 522
T+S+AKAG+ A LNAR S+LAA NP GRYD + + +N+ L PPI+SRFDL FI+ D
Sbjct: 780 TVSIAKAGIVARLNARASVLAAGNPKLGRYDHSLPVSKNIDLPPPILSRFDLIFIVEDIP 839
Query: 523 SEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSF-KPVITEEAGKLLVEYYX 581
+ D +A+ I+D+H + E++ + L +YI++AR + +P +T+EA KLL+++Y
Sbjct: 840 EKTKDTLLAKHILDIHTDYEKAKPLI-DTQLLKKYISYARRYIRPKLTQEAKKLLLDFYV 898
Query: 582 XXXXXXXXXXXX---XWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSII 638
+T RQLE+++RL+E AKM T EA RL+ S+
Sbjct: 899 NMRLSGVKASKEGPPAIAMTPRQLEALIRLSEAHAKMALKTKATIEDAEEAIRLMYYSLR 958
Query: 639 RV 640
+V
Sbjct: 959 KV 960
Score = 77.8 bits (183), Expect = 1e-12
Identities = 67/232 (28%), Positives = 104/232 (44%), Gaps = 27/232 (11%)
Query: 25 FQDFLEEFKEDNE--IKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYP 82
F+ FL +F++ KY + + +L + F+D+ +++ LA I
Sbjct: 18 FKRFLWDFRDRRTGMFKYRERISHMALMGQRSLLIDFNDITLFDRGLAHIIENNPDTAIE 77
Query: 83 FLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVR 142
+ AI L E + DK Y F + ++RELT+ IG + + G + R
Sbjct: 78 AASIAIKE--LMRRENPEYAESVDK-FYPRFRNPSKVLRIRELTSEYIGKFVAVEGILTR 134
Query: 143 THPVHPELVQGTFYTI--------------------PTICRNPVCANRRRFMLDADKSVF 182
V LV+ F P+ C P+C +F L +KS F
Sbjct: 135 LTRVEARLVKAVFKHAECGAEFEWPEEGEMGERIEKPSYC--PICGKTGKFQLLLNKSRF 192
Query: 183 VDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVP 234
+D+QKI +QE E+P G IPRS+EV+L + V+S + GDR TG L V+P
Sbjct: 193 IDWQKIVVQEKPEEIPPGQIPRSIEVVLTGDLVDSARPGDRVLVTGILRVMP 244
>UniRef50_Q389T6 Cluster: Minichromosome maintenance (MCM) complex
subunit, putative; n=3; Trypanosoma|Rep: Minichromosome
maintenance (MCM) complex subunit, putative -
Trypanosoma brucei
Length = 711
Score = 173 bits (421), Expect = 2e-41
Identities = 116/361 (32%), Positives = 186/361 (51%), Gaps = 18/361 (4%)
Query: 284 SVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGN 343
+ Q ++ R E H M+ + +E + YEM R+ ++ L SL PSI G
Sbjct: 274 ATQQIAVRACFVENSRHSAVRGPMQTIDSLEESGRFYEMVRNPQWFSMLCGSLAPSIFGL 333
Query: 344 NEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSG 403
VK ++L + GG T ++ T R +I++ IVGDP KSQLL+ + PR+ +
Sbjct: 334 EHVKEAIILAVVGG---TAMKKRT-RSNIHLLIVGDPGLGKSQLLRAACTVAPRSSFVCA 389
Query: 404 KASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQT 463
SS+ GLT + RD + + EAGA++ D G+ CIDE DK P + A+ E MEQ++
Sbjct: 390 HTSSSCGLTLTLSRDPTTGETSFEAGAVVHGDGGITCIDEIDKGVP-EHNALLEVMEQES 448
Query: 464 ISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESS 523
+S+AKAG+ ++ T+IL A NPIGGR+D KS+ N+ LSP + +RFD+ + S+
Sbjct: 449 VSMAKAGMVFSVPVHTAILTAGNPIGGRFDDTKSIPANLNLSPALFTRFDIVICMRSPSA 508
Query: 524 EMVDYAIARKIVDLH-CNKEESYDCVYSR-------DDLLRYIAFAR-SFKPVITEEAGK 574
+ +++ ++ LH C K V + + R+IAF R + P + +EA
Sbjct: 509 D-ASRSLSDHVLQLHRCVKGGGSRTVAKTSGPPLPLETVQRFIAFCRHNCHPSLRQEACD 567
Query: 575 LLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN 634
+L YY +T R L++++R++E AK+ VT A L+
Sbjct: 568 VLKAYYLQRRAEAAMGELA---VTPRFLQALIRVSEARAKVELRHEVTAEDARYAVELMK 624
Query: 635 K 635
+
Sbjct: 625 R 625
>UniRef50_Q4UH54 Cluster: DNA replication licensing factor Mcm2,
putative; n=2; Theileria|Rep: DNA replication licensing
factor Mcm2, putative - Theileria annulata
Length = 1019
Score = 171 bits (417), Expect = 5e-41
Identities = 102/251 (40%), Positives = 151/251 (60%), Gaps = 26/251 (10%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGV------------ 358
+TD++ + ++ + L S+ PS+ G + VK+G+LLML GG
Sbjct: 395 ITDEDRARFKYLAGRNDTITVLTNSVAPSLCGLSLVKKGILLMLVGGHLNPINDTQQTAY 454
Query: 359 ------AKTTIE-----GTT---LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGK 404
+TT E G T LRGDI+V +VGDP KSQLL+ V + P + T+G+
Sbjct: 455 NSKNLDTETTNENLFSSGETRENLRGDIHVLLVGDPGCGKSQLLRFVMTLLPNTISTTGR 514
Query: 405 ASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTI 464
S+ GLTAA+V+DEE+ + +E GA+++ D + IDEFDKM+ D+VAIHE MEQQT+
Sbjct: 515 GSTGVGLTAAIVQDEETGERKVEGGAMVMGDRKIVLIDEFDKMNYADRVAIHEVMEQQTV 574
Query: 465 SLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSE 524
S+AKAG+ TLNAR ++LAAANP+ G + + + + ++SRFDL FI+ D ++E
Sbjct: 575 SVAKAGIHTTLNARCTVLAAANPLYGCWAEDMQINEQLNFEYSLLSRFDLIFIVRDVNNE 634
Query: 525 MVDYAIARKIV 535
+ D IA I+
Sbjct: 635 IQDDRIADAIL 645
Score = 35.9 bits (79), Expect = 4.3
Identities = 28/94 (29%), Positives = 48/94 (51%), Gaps = 12/94 (12%)
Query: 597 ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEP 656
++ R LE+++RL+ AK+ S ++T HV A +LLN +I D++ +D +
Sbjct: 818 VSPRTLEAILRLSTAFAKLKLSRYITKEHVKAAVKLLNYTIF----GDVYTTKDSSK--- 870
Query: 657 SMDVDQDEPNGTAETPSNGDSAPKKKLALSFEEY 690
D D D +G+ + D ++L S EEY
Sbjct: 871 -EDEDVDFSSGS----ESDDDFDDQELLSSDEEY 899
>UniRef50_Q58884 Cluster: Uncharacterized MCM-type protein MJ1489;
n=10; Methanococcales|Rep: Uncharacterized MCM-type
protein MJ1489 - Methanococcus jannaschii
Length = 682
Score = 171 bits (415), Expect = 8e-41
Identities = 113/348 (32%), Positives = 188/348 (54%), Gaps = 31/348 (8%)
Query: 306 DMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEG 365
+++ ++T+ + + + ++++ +++ N L L P I G++ +K+ VLL GV K
Sbjct: 262 EVKIKLTNSDIENIKKIAKRKDVVNILADRLIPEIKGHSAIKKAVLLQQIKGVKKPG--- 318
Query: 366 TTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD-- 423
R DI++ ++ DP K+ +L++++EI P +Y S ++ GLTAAVVR++
Sbjct: 319 --KRADIHILLITDPGIGKTVILRKIAEI-PGNLYGSVTTATGVGLTAAVVREKTEIGED 375
Query: 424 -FVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSIL 482
+VI+ G L+ A G CIDE ++ Q + EAME QTI ++K G+ A L A +IL
Sbjct: 376 TWVIKPGLLVKAHKGTACIDELT-VNKELQSYVLEAMESQTIHISKGGINAKLPAECAIL 434
Query: 483 AAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH---- 538
AA NP GR++ S+ + + + P++SRFDL F + D S + D IA IVDLH
Sbjct: 435 AACNPRWGRFNPEVSVAEQINIPAPLLSRFDLIFPIRDVSDKDKDKDIAEYIVDLHRAYL 494
Query: 539 ---CNKEESYDCV------YSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXX 589
N+E D + ++ +++YI +AR KP+I+E+A +L V YY
Sbjct: 495 DEKINREMGLDYLEVDGVKIDKEFIIKYIYYARQKKPIISEKAKELFVNYYVEMRKKH-- 552
Query: 590 XXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
+IT RQLE+ +R+AE AK V EA ++ + +
Sbjct: 553 ------QITARQLEAAIRIAEAHAKAKLKDVVDEEDAKEAINIITECL 594
>UniRef50_A4HNF5 Cluster: DNA replication factor, putative; n=5;
Trypanosomatidae|Rep: DNA replication factor, putative -
Leishmania braziliensis
Length = 916
Score = 170 bits (413), Expect = 1e-40
Identities = 116/345 (33%), Positives = 178/345 (51%), Gaps = 22/345 (6%)
Query: 338 PSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPR 397
P + G + VLL GG + T +R I+ VGDPST K+QLL+ + I PR
Sbjct: 322 PHLSGLFAPRLAVLLSALGGTSTTGKTSMHVRNTIHCLYVGDPSTGKTQLLRFAAAIAPR 381
Query: 398 AVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHE 457
+ T+G S++AGLT A + E ++V+E GAL+L+D G C IDE + P D+ ++HE
Sbjct: 382 STSTTGMGSTSAGLTVAAAK--EHGEWVLEPGALVLSDGGSCIIDELRTVSPADRASLHE 439
Query: 458 AMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFI 517
AMEQQTIS+AK G+ L ++L+A NP R R + + + P++SRFD F+
Sbjct: 440 AMEQQTISVAKGGLVTKLRTSCAVLSACNPPARRGGRTE-----IGVGGPLLSRFDFIFL 494
Query: 518 LIDESSEMVDYAIARKIVDLHCNKEESY-DCVYSRDDLLRYI-----AFARSFKPVITEE 571
L D VD IA ++ + + S + + +++ RY+ +A + P++++
Sbjct: 495 LWDTPQPEVDARIASHMLRANTGAQTSLEEDELTVEEVARYLWWVRTQYAAADGPLLSDS 554
Query: 572 AGKLLVEYYXXXXXXXXX-XXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAY 630
A LL YY +TVR LES+VRLA+ AK+H T A
Sbjct: 555 AADLLGRYYEIQRQRGASPSLDDAVPVTVRFLESLVRLAQAHAKLHLQTVCTLEDAAMAV 614
Query: 631 RLLNKSIIRVEQPDIHLDEDEP-QCEPSMDVDQ----DEPNGTAE 670
L+ ++ ++ P LD EP C S ++D+ DEP A+
Sbjct: 615 FLMERTAYSLKCP---LDAVEPGVCSSSRELDEVFLSDEPEALAQ 656
>UniRef50_Q0W2N3 Cluster: Putative DNA replication licensing factor;
n=1; uncultured methanogenic archaeon RC-I|Rep: Putative
DNA replication licensing factor - Uncultured
methanogenic archaeon RC-I
Length = 862
Score = 169 bits (412), Expect = 2e-40
Identities = 122/413 (29%), Positives = 205/413 (49%), Gaps = 44/413 (10%)
Query: 55 LEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFV 114
L + F ++ K++ LA ++ P L + L+L + +K + K + +
Sbjct: 37 LAIEFPNITKFDVRLAEELLNN-----PDLVLSHAEDALTLVDLPVKTQVSAK---IRVI 88
Query: 115 DVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFM 174
VP + +VREL ++ + L+ + G + + V P +++ F C+N + ++
Sbjct: 89 KVPRKTQVRELRSSDVNKLVSLEGTVRKITDVRPRILEAAFECAR--CKNII------YI 140
Query: 175 LDADKSVFVDFQKIRIQETQAELPRGCIPRS----LEVILRAEAVESVQAGDRYDFTGTL 230
F++ + E + + R S + I E+ E+++ G++ T +
Sbjct: 141 PQEGSGKFIEPSYCQCNEEKKGIFRLMYKESRFEDYQRIKIQESPENLKGGEQPQ-TLDI 199
Query: 231 IVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSR 290
V D+ + PG +T + A +G KTA+ + V+
Sbjct: 200 NVSDDLAGIVTPGEFITVTGILRSAQRVNKDG--------------KTAYFDIYLDGVAV 245
Query: 291 RFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGV 350
E +++ ED +++ MSRD +Y +I S+ PSI+G +EVK V
Sbjct: 246 ELEEQEFDEVEISLEDE---------EEILRMSRDPEIYQKVIGSIAPSIYGYDEVKEAV 296
Query: 351 LLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAG 410
LF GV K +G+ +RGDI+V +VGDP AKSQ+L+ V ++ PR VY SGK++S+AG
Sbjct: 297 AHQLFSGVVKELPDGSRIRGDIHVLLVGDPGIAKSQILRYVVKLAPRGVYASGKSASSAG 356
Query: 411 LTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQT 463
LTAA V+DE + +EAGAL+LAD G+ IDE DKM D+ ++HE MEQQ+
Sbjct: 357 LTAAAVKDEFDGQWTLEAGALVLADKGIAAIDEMDKMKNEDRSSLHEGMEQQS 409
Score = 92.7 bits (220), Expect = 4e-17
Identities = 69/201 (34%), Positives = 100/201 (49%), Gaps = 24/201 (11%)
Query: 463 TISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDES 522
+IS+AKAG+ ATL R +IL AANP GR+D +S+ + + P +MSRFDL FIL D+
Sbjct: 576 SISIAKAGILATLKCRCAILGAANPKLGRFDPYESIPDQINMPPSLMSRFDLIFILQDKP 635
Query: 523 SEMVDYAIARKIVDLHCNKE-----ESYDCVYSRDDLLR-----------------YIAF 560
E D IA I+ H E ++ + DD++R Y+A+
Sbjct: 636 EEKRDTNIAGHILKSHFAGELHEHRKNNPASHVTDDMVRTAMSTIKPQIDPKLFRKYVAY 695
Query: 561 A-RSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSG 619
A R P++TE+A ++ +Y +T RQLE +VRLAE A+M S
Sbjct: 696 AKRKVFPIMTEDAKAQIINFYLGLRKQGEGDNAPI-PVTARQLEGLVRLAEASARMRLSD 754
Query: 620 HVTPAHVHEAYRLLNKSIIRV 640
VT V R+ S+ +V
Sbjct: 755 KVTADDVARTIRITMTSLKQV 775
>UniRef50_A5K0L2 Cluster: DNA replication licensing factor MCM8,
putative; n=2; Plasmodium|Rep: DNA replication licensing
factor MCM8, putative - Plasmodium vivax
Length = 1297
Score = 165 bits (400), Expect = 5e-39
Identities = 90/246 (36%), Positives = 142/246 (57%), Gaps = 7/246 (2%)
Query: 298 PTHDLTTEDMRKQMTDKEWD-KVYEMSRDRNLYNN-----LITSLFPSIHGNNEVKRGVL 351
P H D R ++D KV E D + Y L+ SL P I N+ +K G+L
Sbjct: 787 PNHPNHPNDDRHFNQTTQFDAKVLEFIDDMHKYGKNKFYLLVASLCPRIIMNSYIKAGML 846
Query: 352 LMLFGG-VAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAG 410
L L GG + RG+I+ ++GDP KS++L+ VS I +++ ++S G
Sbjct: 847 LSLLGGKTIYDEYKQIKRRGNIHNLLIGDPGLGKSRILQYVSNIIENSLFICSTSTSING 906
Query: 411 LTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAG 470
LTA +D + ++ +E GAL+L+D G+CCIDE DK+ DQ + E ME Q I+++KAG
Sbjct: 907 LTACAFKDATNNEYSLEGGALVLSDKGICCIDELDKISLTDQQSFLECMESQCINISKAG 966
Query: 471 VRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAI 530
+ L R SI+AA+NP G+Y+ K++ +N+ + P+++RFDL F+L D+ SE DY I
Sbjct: 967 IVCNLKTRCSIIAASNPKEGKYNYNKTIFENIKIPFPLLTRFDLVFLLTDKMSEEKDYRI 1026
Query: 531 ARKIVD 536
+ +++
Sbjct: 1027 SNYLIN 1032
Score = 42.7 bits (96), Expect = 0.037
Identities = 22/72 (30%), Positives = 35/72 (48%)
Query: 566 PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAH 625
P +++EA K + ++Y IT+RQLES++RL + A+ S VT H
Sbjct: 1174 PTLSDEAKKYIRKFYLHLRSLSATHSNISSPITIRQLESLIRLCQARARGDLSNVVTLYH 1233
Query: 626 VHEAYRLLNKSI 637
E + K+I
Sbjct: 1234 AKEVVEIYQKTI 1245
>UniRef50_Q4QJG9 Cluster: DNA replication licensing factor,
putative; n=3; Leishmania|Rep: DNA replication licensing
factor, putative - Leishmania major
Length = 993
Score = 164 bits (399), Expect = 7e-39
Identities = 89/205 (43%), Positives = 122/205 (59%), Gaps = 3/205 (1%)
Query: 314 KEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDIN 373
+E + YE++R + L S+ PSI G VK+ +LL + GG G R I+
Sbjct: 521 EETGRFYEVARHPQWFARLTASVAPSIFGMELVKQALLLSIVGG--NRDKNGGETRSSIH 578
Query: 374 VCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALML 433
V +VGDP KSQLL+ + PR+ + SS+ GLT + RD S + EAGA++
Sbjct: 579 VLLVGDPGLGKSQLLRAACAVAPRSAFVCAHTSSSCGLTMTLTRDPVSGETTFEAGAVVH 638
Query: 434 ADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYD 493
D G+ C+DE DK + A+ E MEQ+T+SLAKAG+ ++ RTSILAA NPIGGR+D
Sbjct: 639 GDGGITCLDEIDK-GVQEHKALLEVMEQETVSLAKAGMIFSMPVRTSILAAGNPIGGRFD 697
Query: 494 RAKSLQQNVALSPPIMSRFDLFFIL 518
KSL NV LSP ++SRFD+ L
Sbjct: 698 VRKSLAANVNLSPALLSRFDIIACL 722
>UniRef50_Q38E36 Cluster: Minichromosome maintenance (MCM) complex
subunit, putative; n=1; Trypanosoma brucei|Rep:
Minichromosome maintenance (MCM) complex subunit,
putative - Trypanosoma brucei
Length = 761
Score = 163 bits (395), Expect = 2e-38
Identities = 102/291 (35%), Positives = 157/291 (53%), Gaps = 15/291 (5%)
Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391
L+ S+ P + G + V+L GG + +R I+ VGD ST KSQLL+
Sbjct: 293 LVNSVCPHLAGLFAPRMAVILATLGGTSTVGKTRMHVRSTIHCLFVGDSSTGKSQLLRCA 352
Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451
+ + PR+ T+G S++AGLT A +E ++V+E GAL+L+D GVC IDE + GD
Sbjct: 353 ALLAPRSTSTTGMGSTSAGLTVAA--SKEQGEWVLEPGALVLSDGGVCVIDELRTVSVGD 410
Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511
+ ++HEAMEQQTIS+AKAG+ L S+++A NP + + + P++SR
Sbjct: 411 RASLHEAMEQQTISVAKAGMVTKLRTCCSVISACNP------PTRQNGTEIGVGGPLLSR 464
Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIA-----FARSFKP 566
FD F+L D S D IA I++ + D V S DD+ RY+ ++++ P
Sbjct: 465 FDFVFLLWDTPSPETDDRIATHILN-YSQAGRLPDSVLSLDDVGRYLRWVHAHYSQNGGP 523
Query: 567 VITEEAGKLLVEYYXXXXXXXXXXXXXXW-RITVRQLESMVRLAEGVAKMH 616
++T+ A +L+ YY IT+R LES+VR+ + AK+H
Sbjct: 524 LLTDGASRLIKAYYEMQQRRGAVPNLADCVPITIRLLESLVRVTQAYAKLH 574
>UniRef50_A3CUX8 Cluster: MCM family protein; n=1; Methanoculleus
marisnigri JR1|Rep: MCM family protein - Methanoculleus
marisnigri (strain ATCC 35101 / DSM 1498 / JR1)
Length = 1059
Score = 163 bits (395), Expect = 2e-38
Identities = 124/429 (28%), Positives = 218/429 (50%), Gaps = 42/429 (9%)
Query: 39 KYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAET 98
+Y++ EL + + D + N LA ++ ++ + AI+ L +
Sbjct: 23 QYKRELAELSREYPHNHSLLIDYRKILNNKLAFELLRSPGKVLGDIRDAIVQNKLLKLKD 82
Query: 99 GMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTFYTI 158
G DL + + F ++P + VR++ +I T + + G + +T V P +V F
Sbjct: 83 GQDPDLVN----IRFTNLPQKTNVRDIRADQINTFVSLEGILRKTTEVRPRIVSAVF-RC 137
Query: 159 PTICRN--PVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRG-CIPRSLEVILRAEAV 215
T +N PV RF D+ DF ++T+ +L C + + E+
Sbjct: 138 RTCNKNTDPVPQGYGRF----DEP---DFCPNCERKTRLDLVMNRCRFVDAQKLRIQESP 190
Query: 216 ESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELH 275
E ++ G++ T + V D+ + PG R + G + ++ + G +
Sbjct: 191 EGLRGGEQPQ-TLDIDVTDDLTGMVSPGDRVVVN--------GILRSVQRVN-YGQKSTL 240
Query: 276 YKTAFLAC-SVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLIT 334
+ +L C S++ + F E++ +++++ + ++RD +Y +
Sbjct: 241 FDI-YLECNSIEVAEKEF------------EEV--SISEEDEANIMALARDPMVYKKIAR 285
Query: 335 SLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEI 394
S+ P+I+G ++VK + L LFGG+AK +G+ LRGD++V +VGDP AKSQ+L+ V ++
Sbjct: 286 SIAPTIYGTDDVKEAIALQLFGGIAKDMPDGSRLRGDVHVLLVGDPGIAKSQILRYVVKL 345
Query: 395 TPRAVYTSGKASSAAGLTAAVVRDE-ESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQV 453
+PR +YTSGK+S++AGLTA V+DE + +EAGAL+LAD G+ +DE DKM D+
Sbjct: 346 SPRGIYTSGKSSTSAGLTATAVKDEFGDGRWTLEAGALVLADMGIAAVDEMDKMQKEDRS 405
Query: 454 AIHEAMEQQ 462
A+HEAMEQQ
Sbjct: 406 ALHEAMEQQ 414
Score = 88.6 bits (210), Expect = 6e-16
Identities = 62/201 (30%), Positives = 103/201 (51%), Gaps = 25/201 (12%)
Query: 463 TISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDES 522
+IS+AKAG+ ATL +R ++L AANP GR+D+ + + + + P ++SRFDL F++ D+
Sbjct: 773 SISVAKAGITATLKSRCALLGAANPKLGRFDQFVPIGEQINMPPSLLSRFDLIFVMTDQP 832
Query: 523 SEMVDYAIARKIVDLH----CNKEESYDCVYSRDD------------------LLRYIAF 560
D AIA+ I+ H K+ Y+ + DD L +YIA+
Sbjct: 833 EVQRDGAIAQHIIKTHSVGELIKQHEYEPLPDVDDAYIERALAPVIPDIDPTLLRKYIAY 892
Query: 561 A-RSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSG 619
A R+ P++++ A + L+ YY +T RQLE++VRLAE A+M S
Sbjct: 893 AKRTCFPILSDGAKEALIAYYMRLRNLASGNKPV--PVTARQLEALVRLAEASARMRLSN 950
Query: 620 HVTPAHVHEAYRLLNKSIIRV 640
V ++++ + +V
Sbjct: 951 TVDTEDTDRILKIVDACLRQV 971
>UniRef50_A0ZYP8 Cluster: Putative uncharacterized protein; n=1;
Archaeal BJ1 virus|Rep: Putative uncharacterized protein
- Archaeal BJ1 virus
Length = 704
Score = 156 bits (378), Expect = 3e-36
Identities = 103/336 (30%), Positives = 170/336 (50%), Gaps = 19/336 (5%)
Query: 335 SLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEI 394
SL P ++GN+E+KR ++ + GG + RG+ ++ ++GDP TAKS+L+++V E+
Sbjct: 290 SLAPKVYGNDEIKRNLIRAMVGGSKVVYGDDDHDRGEFHILLIGDPGTAKSKLIQRVEEL 349
Query: 395 TPRAVYTSGKASSAAGLTAAVVRDE-ESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQV 453
R V SGK ++ AG+TA+ V+D+ + ++AGA + A G CIDE D M +
Sbjct: 350 GWRTVGVSGKGATVAGVTASAVQDDFGDGEATLKAGAFVKAHKGAVCIDELDDMPADVRA 409
Query: 454 AIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFD 513
A+ + M +Q I + K G+ AT+ +++AAANP GR+D+ + + L ++SRFD
Sbjct: 410 AMLDPMSKQKIHVNKWGINATMRTEAAVVAAANPKHGRFDQYEPIGDQFDLESNLLSRFD 469
Query: 514 LFFILIDESSEMVDYAIARKIV-------------DLHCNKEESYDCVYSRDDLLRYIAF 560
L F L D D I+ I+ +L N E+ RD L +++A
Sbjct: 470 LIFTLSDTPDPDEDERISEHILRARDAAKRQMTGRELSENGAETISTPVDRDILRKWVAL 529
Query: 561 A-RSFKPVI-TEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCS 618
A R +PV +E+ + L E + +T R+LE ++R+AE AK+ S
Sbjct: 530 AKRQPEPVFESEKVFEWLQESFNTLRGMHGYNEDSPVPVTFRKLEGIIRIAEADAKLEFS 589
Query: 619 GHVTPAHVHEAYRLLNKSI---IRVEQPDIHLDEDE 651
+ H A + S+ + E D+ D E
Sbjct: 590 ETIEMRHAKRAVNAIGDSMQDYAKNEDGDLDADVQE 625
Score = 37.5 bits (83), Expect = 1.4
Identities = 43/198 (21%), Positives = 86/198 (43%), Gaps = 27/198 (13%)
Query: 51 ELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECY 110
E +L + +D++ ++++ +A + + + +L A+ + L D+ +
Sbjct: 40 EQRSLVIDYDELYEFDREIAEDTLSKPEEMGEYLEEALRQFDLPA-------DVDLANAH 92
Query: 111 VSFVDVPTRHKVRE---LTTAKIGTLIRISGQIVRTHPVHPELVQ--------GTFYTIP 159
V ++P H T + G+ I+G++ + V+ +V+ GTF IP
Sbjct: 93 VRVSNLPPEHTYYPGGFSPTDQAGSHRAITGEVSKATDVYSRVVEAAFECKRCGTFSYIP 152
Query: 160 TI---CRNPV----CANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRA 212
+ P C + F ++ D+S F+D Q++RI T E+ G ++V
Sbjct: 153 QTDGGFQEPHECQGCERQGPFRVNFDQSEFIDAQQLRI-ATPPEIASG-TGHEIDVTAED 210
Query: 213 EAVESVQAGDRYDFTGTL 230
+ + V GDR TGT+
Sbjct: 211 DLADLVTVGDRVTITGTI 228
>UniRef50_Q5JEJ0 Cluster: DNA replication licensing factor, MCM2/3/5
family; n=1; Thermococcus kodakarensis KOD1|Rep: DNA
replication licensing factor, MCM2/3/5 family -
Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
Length = 914
Score = 156 bits (378), Expect = 3e-36
Identities = 115/342 (33%), Positives = 171/342 (50%), Gaps = 17/342 (4%)
Query: 304 TEDMRK-QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTT 362
T+D+ ++T ++ K +M +D + LI SL P+I G K+ VLL LF G
Sbjct: 491 TKDIEDLEITPEDVQKFQDMVKDPEFDSKLIRSLAPAITGREVEKKAVLLALFSG-EDYD 549
Query: 363 IEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESF 422
I GT +R +V + GD ST KS++++ ++I P V+++G SS GLTAA+ D
Sbjct: 550 ITGTHVRKRSHVLLFGDASTGKSEIIRHAAQIAPGGVHSTGTHSSGVGLTAAI--DSMDG 607
Query: 423 DFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSIL 482
V+ AG L+LAD GV +DE DKM D + +A+EQ KAG L AR ++
Sbjct: 608 VRVLRAGVLVLADRGVAALDELDKMREEDYDKMLDALEQGWFPYNKAGFNTRLMARAVVI 667
Query: 483 AAANPIGGRYDR--AKSLQQNVAL-SPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC 539
AAANP GG +DR K + L P SRFDL + + V IA ++D H
Sbjct: 668 AAANPPGGEFDRHNYKPFDELKRLFDQPFYSRFDLIIPTFRNTEDSVLEEIADAVLDKHE 727
Query: 540 NKEESYDCVYSRDDLLRYIAFARSFKP-VITEEAGKLLVEYYXXXXXXXXXXXXXXWRIT 598
K E Y + L ++IA+AR P V+ +A + +++ Y
Sbjct: 728 GKIEP---PYDSELLTKFIAYARREIPRVVLPQALRGVMKKYMVDLAKAIGSA------A 778
Query: 599 VRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRV 640
R +E+++RL E A+MH T A A L ++ I R+
Sbjct: 779 PRAMEAIIRLTEAHARMHLRKEATLADFLAAKELFDEMITRL 820
>UniRef50_Q57809 Cluster: Uncharacterized MCM-type protein MJ0363;
n=1; Methanocaldococcus jannaschii|Rep: Uncharacterized
MCM-type protein MJ0363 - Methanococcus jannaschii
Length = 759
Score = 155 bits (375), Expect = 6e-36
Identities = 110/355 (30%), Positives = 181/355 (50%), Gaps = 23/355 (6%)
Query: 301 DLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAK 360
D E++ K + +K+ + + +++D+N+ L F + G + +KR VLL L +
Sbjct: 325 DEDIEEIAKNLNEKDLELINRIAKDKNVIQKLSDYAFREVTGYDMIKRAVLLQLVS--SG 382
Query: 361 TTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEE 420
T I+ +R I++ ++ DP KS L++ + + P SS GL +VVR++
Sbjct: 383 TNID---MRTSIHILMISDPGVGKSTLMESLIQKFPFVKKVYAVTSSGPGLVGSVVREKA 439
Query: 421 SF--DFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGV-RATLNA 477
F +V++AG L AD GV CIDEF + + MEQQ I + KAGV A L A
Sbjct: 440 EFGDSWVLKAGVLTEADGGVVCIDEFSRNKEVYDYLLG-VMEQQKIEINKAGVIDAVLPA 498
Query: 478 RTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDL 537
R +ILAA NP GR++ ++ + + L ++ RFDL F++ D+ + D IA +D
Sbjct: 499 RVAILAACNPRFGRFNPDLTVWEQINLPKELLDRFDLIFVIKDKIDKKKDEDIADFSIDN 558
Query: 538 HCNKEES-----------YDCVYSRDD-LLRYIAFARSFKPVITEEAGKLLVEYYXXXXX 585
+ +K + V D+ LL+Y+ +AR +P I++EA K++ EYY
Sbjct: 559 YNSKVRERKGKSSGKKFVINGVELNDELLLKYVLYARQIEPEISDEARKIIKEYY--VSV 616
Query: 586 XXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRV 640
+ I+ RQL S++RLA AK+ S V EA RL++ + ++
Sbjct: 617 RKMSEAKGTFGISARQLGSIIRLAVAHAKLRLSEVVKAVDAEEAIRLVDTCLKQI 671
>UniRef50_A4R567 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 877
Score = 152 bits (369), Expect = 3e-35
Identities = 86/199 (43%), Positives = 114/199 (57%), Gaps = 19/199 (9%)
Query: 106 DKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF---------- 155
DK ++F ++P +VR L IG L+ ISG + RT V PEL TF
Sbjct: 376 DKLFSIAFYNLPLVSRVRALRAKNIGQLLSISGTVTRTSEVRPELSLATFMCQACKAIVP 435
Query: 156 -------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEV 208
YT PT C N C NR + LD +S FVD+QK+RIQE +E+P G +PR+++V
Sbjct: 436 NVEQTFRYTEPTQCPNDNCQNRLAWQLDIRQSTFVDWQKVRIQENSSEIPTGSMPRTMDV 495
Query: 209 ILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLAN--EGQMEGIKGL 266
I+R E V+ +AG++ FTG LIVVPDV + +PG RA K E G+ GL
Sbjct: 496 IMRGEIVDRAKAGEKCVFTGALIVVPDVSQMGLPGLRATAVRDDKAPRPAEAGGSGVTGL 555
Query: 267 KALGVRELHYKTAFLACSV 285
K+LGVR+L Y+ AFLAC V
Sbjct: 556 KSLGVRDLTYRLAFLACMV 574
Score = 130 bits (315), Expect = 1e-28
Identities = 88/296 (29%), Positives = 147/296 (49%), Gaps = 25/296 (8%)
Query: 520 DESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEY 579
DE +E D +A IV +H ++E+ + +S + L RYI FAR+F+P TEEA + LV++
Sbjct: 588 DECNERTDRHLAEHIVGIHQLRDEAIEPEFSTEQLQRYIRFARTFRPEFTEEAKQTLVKH 647
Query: 580 YXXXXXXXXXXXXX--XWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
Y +RITVRQLESM+RL+E +AK++C + V EAY LL +SI
Sbjct: 648 YRELRADDAQGGVGKNSYRITVRQLESMIRLSEAIAKVNCVEEIASHMVDEAYNLLRQSI 707
Query: 638 IRVEQPDIHLDEDEPQCEPSMDV-----------DQDEPNGTAETPSNGDSA--PKKKLA 684
I VE D+ +D++E E + D+D P G E N + +K+
Sbjct: 708 ISVEHDDVEVDDEEDAPEDDQETLRRAAQAGQAPDEDSPMGGEEAAQNASTTTPASQKVT 767
Query: 685 LSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELL 744
++ E++ ++ NM+V + + G+ +V+WYLEQ + ++ SE++
Sbjct: 768 ITHEKWVAMLNMMVQRVAE-----DEVSGSGEGISGDDLVNWYLEQ--KEDELASEEDFN 820
Query: 745 ERKTLVEKVIDRLMYHDQVIIPLSTTGLRGTQKSSEQDIED--DPLLVVHPNYVVD 798
K L V+ + M + +++ + G + E + V+HPN V+
Sbjct: 821 REKKLATMVLKK-MVKEHILMAVEAQSEDGDAATVEGSSARAVRVVYVLHPNCAVE 875
Score = 48.0 bits (109), Expect = 0.001
Identities = 30/95 (31%), Positives = 47/95 (49%), Gaps = 14/95 (14%)
Query: 12 QVKDEVGIRCQKLFQDFLEEFKEDNE-------------IKYEKHAKELLKPELSTLEVS 58
+V+D VG+ Q+ F++F+E + E+ + + Y + +LSTL V
Sbjct: 235 RVEDRVGLAIQQHFEEFIESYTEEPDSSGQPASSAVTTRVYYVAQIHGMRTHQLSTLYVD 294
Query: 59 FDDVEKY-NQNLATTIIEEYYRIYPFLNRAILNYI 92
F + Y N NLA I+ EYYR P+L + N I
Sbjct: 295 FKHLSTYQNGNLAEAIVREYYRFLPYLTTGLHNMI 329
>UniRef50_A4IIB8 Cluster: MGC146393 protein; n=1; Xenopus
tropicalis|Rep: MGC146393 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 675
Score = 151 bits (366), Expect = 7e-35
Identities = 72/153 (47%), Positives = 105/153 (68%), Gaps = 1/153 (0%)
Query: 391 VSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPG 450
V + PR VY G ++ +GLT + RD + DF +EAGAL+L D G+C IDEFDKM
Sbjct: 412 VCNVAPRGVYVCGNTTTTSGLTVTLSRDSATGDFGLEAGALILGDQGICGIDEFDKMGNQ 471
Query: 451 DQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMS 510
Q A+ EAMEQQ+ISLAKAG+ +L ARTSI+AAANP+GG Y++ K++ +N+ + ++S
Sbjct: 472 HQ-ALLEAMEQQSISLAKAGIVCSLPARTSIIAAANPVGGHYNKGKTVSENLKMGSALLS 530
Query: 511 RFDLFFILIDESSEMVDYAIARKIVDLHCNKEE 543
RFDL FIL+D +E D+ ++ ++ + +E
Sbjct: 531 RFDLVFILLDTPNEDHDHLLSEHVMAMRAGAKE 563
Score = 42.3 bits (95), Expect = 0.049
Identities = 29/81 (35%), Positives = 42/81 (51%), Gaps = 5/81 (6%)
Query: 156 YTIPTICRNPVCANRRRFMLDADK--SVFVDFQKIRIQETQAELPR--GCIPRSLEVILR 211
Y +PT C P C R F + +V VD+Q I++QE ++ R G IPR++E L
Sbjct: 249 YAVPTKCPVPECRGRS-FTANRSSPLTVTVDWQTIKVQELMSDDQREAGRIPRTVECELI 307
Query: 212 AEAVESVQAGDRYDFTGTLIV 232
+ V+S GD TG + V
Sbjct: 308 QDLVDSCVPGDMVTVTGIVKV 328
>UniRef50_A7D3N7 Cluster: MCM family protein; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: MCM family protein -
Halorubrum lacusprofundi ATCC 49239
Length = 717
Score = 149 bits (361), Expect = 3e-34
Identities = 103/321 (32%), Positives = 160/321 (49%), Gaps = 18/321 (5%)
Query: 335 SLFPSIHGN--NEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVS 392
S+ P + G + +KR ++L + GG +G+ RG I++ +VGDPST KS L+ Q
Sbjct: 303 SIAPGVFGEQYDHMKRAIVLAVVGGDWVEGKDGSVERGSISMLLVGDPSTGKSALINQAE 362
Query: 393 EITPRAVYTSGKASSAAGLTAAVVRDEESF-DFVIEAGALMLADNGVCCIDEFDKMDPGD 451
PR+V SGK + AG+TA+ VRD+ S ++ ++AGA + A+ G+ IDE D M P
Sbjct: 363 SNAPRSVGVSGKGAREAGITASAVRDDFSDGEWTLKAGAFVKANGGIVRIDELDDMPPDV 422
Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511
+ A+ E M I+++KAG+ ATL R ++AAANP GR+D + + + V L ++SR
Sbjct: 423 RAAMLEPMANGKINVSKAGINATLQTRVGVIAAANPKYGRFDPYEPVVEQVELGSTLISR 482
Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKE--------------ESYDCVYSRDDLLRY 557
FDL F + + +AR IV +K+ + YD + L ++
Sbjct: 483 FDLGFTVTETDEVNTVKQVARDIVGRREHKKRLDVAPETIEPGETDKYDPPVRSELLRKW 542
Query: 558 IAFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMH 616
+A A PVI E + + T R LE+ +RLAE AK+
Sbjct: 543 LALAGDQPSPVIASEELEQRIADEFSDFKTKHMGEDAPVPATWRDLEAQLRLAEAAAKLE 602
Query: 617 CSGHVTPAHVHEAYRLLNKSI 637
S + H A L +S+
Sbjct: 603 FSETIEERHFKTALSLTMRSM 623
Score = 45.2 bits (102), Expect = 0.007
Identities = 48/200 (24%), Positives = 87/200 (43%), Gaps = 29/200 (14%)
Query: 51 ELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECY 110
E +L V +D++ ++++ +A I+ + + +L A+ N+ L D+ +
Sbjct: 51 EQRSLVVDYDELYEFDREIAEDILAKPDEMQEYLEEALRNFDLPA-------DVSLDRAH 103
Query: 111 VSFVDVPTR--HKVRELTTAKIGT---LIRISGQIVRTHPVHPELVQ--------GTFYT 157
V ++P H + K+ I + G+IV VHP++ + GT
Sbjct: 104 VRVANLPDEYTHYPGHFSPTKVHNDQPYIGVEGEIVAGSDVHPKVTETAFECKRCGTMTY 163
Query: 158 IPTICRN-------PVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVIL 210
IP R C + F ++ D+S F+D QKIR+ E E+ G +S+++ +
Sbjct: 164 IPQTDRGYQEPHECQGCERQGPFRVNFDQSEFIDAQKIRLSE-PPEVAGG-EGQSIDIFV 221
Query: 211 RAEAVESVQAGDRYDFTGTL 230
+ V GDR TG L
Sbjct: 222 EDDLAGEVTTGDRVTITGRL 241
>UniRef50_Q58371 Cluster: Uncharacterized MCM-type protein MJ0961;
n=6; Methanococcales|Rep: Uncharacterized MCM-type
protein MJ0961 - Methanococcus jannaschii
Length = 762
Score = 147 bits (357), Expect = 9e-34
Identities = 107/352 (30%), Positives = 171/352 (48%), Gaps = 35/352 (9%)
Query: 321 EMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDP 380
E+ R +N+ + L L I G VK+ + L G K +GT LR D ++ ++ DP
Sbjct: 327 ELGRKKNIIDILSNYLISQIKGYELVKKAIFLQQIKGAFKFLPDGTPLRRDSHILLITDP 386
Query: 381 STAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRD--EESFDFVIEAGALMLADNGV 438
KS +L++++ + P+ Y S ++ GLTA V R+ E +V++ G + A+ G
Sbjct: 387 GIGKSTMLRRIARLFPQNAYASVTTATGGGLTAIVTREATEIGDGWVVKPGVFVRANEGT 446
Query: 439 CCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSL 498
CIDE +D I EAME QTI + K G+ L AR ++LAA NP GR+DR ++
Sbjct: 447 ACIDELT-VDKNVMKYILEAMESQTIHVNKGGINVKLPARCAVLAACNPKRGRFDRNLTV 505
Query: 499 QQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC-NKEESY--------DCVY 549
+ + + P++SRFDL F L+D+ + D IA I++ H + Y D +
Sbjct: 506 IEQIDIPAPLLSRFDLIFPLMDKPNRKSDEEIAEHILNTHIETATKDYKILGAIDIDGIT 565
Query: 550 SRDDLLR-YIAFARS--------------------FKPVITEEAGKLLVEYYXXXXXXXX 588
+ LL+ YI +ARS P +T++A K++ +YY
Sbjct: 566 VDEKLLKYYIIYARSCAYIEENQDLYLGEFDETKLIMPYLTDKAKKMIKKYYLEMRKLGE 625
Query: 589 XXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRV 640
IT RQLE+++R+AE AK S V A +++ + +V
Sbjct: 626 GDNPI--PITARQLEAIIRIAEMHAKARLSDKVEDVDAEVAISIIDDCLKQV 675
>UniRef50_A6UWD0 Cluster: MCM family protein; n=1; Methanococcus
aeolicus Nankai-3|Rep: MCM family protein -
Methanococcus aeolicus Nankai-3
Length = 724
Score = 145 bits (352), Expect = 4e-33
Identities = 99/333 (29%), Positives = 161/333 (48%), Gaps = 20/333 (6%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRG 370
+T+ + + +Y++++D + L + G +EVK+ + L GV K R
Sbjct: 309 ITEDDIENIYKIAKDPEVIEKLANYMLRETKGMDEVKKAIFLQQVKGVEKGD-----KRR 363
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESF--DFVIEA 428
++N+ ++ DP KS ++ Q+ ++ P Y + +S AGL + +++ F +V++
Sbjct: 364 NLNILLITDPGVGKSTMMHQLKKL-PNTKYATMSGASGAGLIGGINKEKTEFGESWVVKP 422
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPI 488
G LAD G C+DEF + +H+AME Q + K L AR + LAA NP
Sbjct: 423 GIYALADGGTVCLDEFTH-NKEVMPYVHDAMESQMAKITKMQNNLELPARCATLAACNPK 481
Query: 489 GGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVD------LHCNKE 542
GRYD S+ + V + P +SRFDL F L D D I + I+ K+
Sbjct: 482 LGRYDSNLSVMEQVPIKPETLSRFDLIFPLRDVPDNENDKDILKFIIRSGNEKIKGTEKK 541
Query: 543 ESYDCVYSRDDLL-RYIAFA-RSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600
+ V D+LL +Y+ + +FKP I++EA +L+++YY IT R
Sbjct: 542 IKINGVELSDELLIKYLHYVDENFKPTISDEAEELIIDYYLKMRELSKNGAIT---ITTR 598
Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
Q ES++RL+E VAK V EA L+
Sbjct: 599 QAESLIRLSEVVAKARLKNEVDTEDAREAIELM 631
>UniRef50_A4FXM1 Cluster: MCM family protein; n=3;
Methanococcus|Rep: MCM family protein - Methanococcus
maripaludis
Length = 626
Score = 144 bits (350), Expect = 6e-33
Identities = 100/332 (30%), Positives = 168/332 (50%), Gaps = 29/332 (8%)
Query: 320 YEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGD 379
Y + + +L + L + P+I G +VK+ +LL G T R D+++ +V D
Sbjct: 294 YCIDNNIDLLDKLSELVVPTIQGYEKVKKAILLQQMKGAYGLT------RNDLHILLVAD 347
Query: 380 PSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD---FVIEAGALMLADN 436
P KS++L+ +S++ P+ +Y S +S GLTA+V +++ + +V + G L+ +
Sbjct: 348 PGVGKSEILRTISKL-PKNLYGSITGTSGVGLTASVEQEKTTVGDSGWVTKPGLLVTKNG 406
Query: 437 GVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAK 496
G +DE +D + EAME Q I +AKAG+ +L A+ +ILAA NP GR+D++K
Sbjct: 407 GTASLDELT-VDKDLSSHLLEAMESQEIHIAKAGINISLPAKIAILAACNPKNGRWDKSK 465
Query: 497 SLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDC--------- 547
L + L+ PI+ RFDL F + + +D IARK + + N E+ D
Sbjct: 466 GLIDQIELTEPILDRFDLIFDMNTGQNSELDAEIARKTIRNYNNGSEAIDTIVETTVTIG 525
Query: 548 --VYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESM 605
V +R+ LL +I +AR+ + I E +++V YY +VR LE++
Sbjct: 526 EDVINREFLLDFIEYARTLQVKIPENINEIMVNYYVAHKKKDNSS-------SVRLLETL 578
Query: 606 VRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
+RL+ AK + ++ A L SI
Sbjct: 579 IRLSTAFAKARLATEISDQDFKNACELFESSI 610
>UniRef50_Q4UHJ8 Cluster: Minichromosome maintenance (MCM),
putative; n=2; Theileria|Rep: Minichromosome maintenance
(MCM), putative - Theileria annulata
Length = 983
Score = 143 bits (347), Expect = 1e-32
Identities = 94/330 (28%), Positives = 169/330 (51%), Gaps = 24/330 (7%)
Query: 325 DRNLYNNLITSLFPSIHGNNEVKRGVLLMLFG----GVAKTTIEGTTL-RGDINVCIVGD 379
+ N + + TSLFP++ G+ +K G+LL LFG G K G + R +I+V ++G+
Sbjct: 563 ESNRFYLIATSLFPNLKGHYHIKVGLLLSLFGFNHTGSNKILRNGNKVKRENIHVLLIGE 622
Query: 380 PSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVC 439
P KS +L +S + V +G S +GL +++D + ++ IEAG L+L +N +
Sbjct: 623 PGVGKSHMLSCISSLGNHIV--NGNNISNSGLNVGIIKDNNN-EYNIEAGLLVLYNNSIL 679
Query: 440 CIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGG--RYDRAKS 497
CIDE DK++ + + E ME+Q +S+AK G+ TLNA T+++ A NP ++
Sbjct: 680 CIDELDKLNSTN--ILLEVMEKQKVSIAKGGIIKTLNANTTLICALNPTHSKFKFSNENI 737
Query: 498 LQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL-R 556
+ N+ LS ++SRFDL F++I++ + D + + YD Y + L+
Sbjct: 738 IANNIKLSTSLLSRFDLIFLIINDKNNYYDKCDENNELVRKLKSFQKYD--YLNNVLINE 795
Query: 557 YIAFARSF-KPVITEEAGKLLVEYYXXXXXXXXX--------XXXXXWRITVRQLESMVR 607
YI +++ + P T+EA +L +++ ++T+RQL+ ++R
Sbjct: 796 YIEYSKKYVNPKFTKEAKLMLYKFFKEILEMSNNNCDANGNPINSCLMKVTIRQLQGLIR 855
Query: 608 LAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637
L + A+ +T HV + + +I
Sbjct: 856 LCKSRARGDLLNVITVDHVKDVIEIFKNTI 885
>UniRef50_Q0UY98 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 317
Score = 141 bits (342), Expect = 6e-32
Identities = 66/101 (65%), Positives = 78/101 (77%)
Query: 369 RGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEA 428
RGDIN+ + GDPSTAKSQLL+ V I PR VYTSGK SSA GLTA V RD E+ V+E+
Sbjct: 11 RGDINILLCGDPSTAKSQLLQYVHRIAPRGVYTSGKGSSAVGLTAYVTRDPETRQLVLES 70
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469
GAL+L+D GVCCIDEFDKM + +HE MEQQT+S+AKA
Sbjct: 71 GALVLSDGGVCCIDEFDKMSEATRSVLHEVMEQQTVSIAKA 111
Score = 56.0 bits (129), Expect = 4e-06
Identities = 36/87 (41%), Positives = 48/87 (55%), Gaps = 3/87 (3%)
Query: 554 LLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITV--RQLESMVRLAE 610
L YI++AR+ +P IT+ A K LVE Y RIT RQLESM+RL+E
Sbjct: 128 LTAYISYARANCQPKITDAAQKALVEAYVAMRALGADIRSQERRITATTRQLESMIRLSE 187
Query: 611 GVAKMHCSGHVTPAHVHEAYRLLNKSI 637
AKM + VT V+EA RL+ ++
Sbjct: 188 AHAKMRLAEEVTADDVNEAVRLIKSAL 214
>UniRef50_Q4U9G0 Cluster: DNA replication protein (MCM homologue),
putative; n=3; Theileria|Rep: DNA replication protein
(MCM homologue), putative - Theileria annulata
Length = 945
Score = 136 bits (329), Expect = 2e-30
Identities = 94/278 (33%), Positives = 152/278 (54%), Gaps = 23/278 (8%)
Query: 354 LFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTA 413
+F GV K G R ++ VGDP+T KS LL+ +EI+ R V G ++ GLT
Sbjct: 568 VFEGVKK---RGNRTRTQCHILFVGDPATGKSHLLEYATEISYRHVSVIGTNCTSVGLTC 624
Query: 414 AVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRA 473
+VRD D ++ AGAL+LA G+CCIDEF ++ D+ +HEAMEQQ IS+AK+G++
Sbjct: 625 TIVRD--GGDTMLAAGALVLASGGICCIDEFSEIKNDDKSCLHEAMEQQVISVAKSGLKC 682
Query: 474 TLNARTSILAAANPIGGR------YDRAKSLQQ---NVALSPPIMSRFDLFFILIDESSE 524
TLN + +I+A++N R YD S ++ N+ P+++RFDL ++ D S+E
Sbjct: 683 TLNCQCTIVASSNYKFARQNNKRKYDDQLSDERRIININTPLPLLTRFDLIIVMTDNSTE 742
Query: 525 ---MVDYAI---ARKIVDLHCNKEESYDCVYSRDDLLRYIAFAR-SFKPVITEEAGKLLV 577
+V++ + +++I + + + D S + + YI F R + P IT +L++
Sbjct: 743 DLDIVEFLLEDDSQRINTTSSDDKSNLDW-SSVNTVKNYIQFVRENLMPSITPSC-QLII 800
Query: 578 EYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKM 615
Y TVR +ES+VRL++ A++
Sbjct: 801 NRYYDEIRSISFNMEYGGGPTVRTIESIVRLSQAHARL 838
>UniRef50_Q8I5T7 Cluster: Minichromosome maintenance protein,
putative; n=4; root|Rep: Minichromosome maintenance
protein, putative - Plasmodium falciparum (isolate 3D7)
Length = 1024
Score = 130 bits (314), Expect = 1e-28
Identities = 68/185 (36%), Positives = 113/185 (61%), Gaps = 6/185 (3%)
Query: 307 MRKQMTDKEWDKVYEMSR-DRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEG 365
+ K++ K + +++M + N + LI+S P I N+ +K G+LL L GG KT +
Sbjct: 554 LNKEIDSKVLEFIHDMEKVGYNKFYLLISSFCPRIIMNSYIKAGLLLSLLGG--KTIYDD 611
Query: 366 TTL---RGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESF 422
RG+I+ ++GDP KS++L+ +S I ++++ +++ GLTA V+D +
Sbjct: 612 NNQIKRRGNIHNLLIGDPGLGKSRILQYISNIMEKSLFICSTSTTINGLTACAVKDTTNN 671
Query: 423 DFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSIL 482
++ +E GAL+L+D GVCCIDE DK+ DQ + E ME Q+I++ KAG+ L R +I+
Sbjct: 672 EYSLEGGALVLSDKGVCCIDELDKISLNDQQSFLECMENQSINITKAGIVCNLKTRCTII 731
Query: 483 AAANP 487
AA+NP
Sbjct: 732 AASNP 736
Score = 44.4 bits (100), Expect = 0.012
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 1/82 (1%)
Query: 557 YIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKM 615
YI + R + P ++E+A K + ++Y IT+RQLES++RL + A+
Sbjct: 846 YIKYCRKYIFPKLSEDAKKYIRKFYLHLRNLANTHNDISVPITIRQLESLIRLCQARARA 905
Query: 616 HCSGHVTPAHVHEAYRLLNKSI 637
S VT H E + K+I
Sbjct: 906 DLSHMVTLKHAKEVVEIYQKTI 927
>UniRef50_Q8I1S4 Cluster: DNA replication licensing factor, putative;
n=2; cellular organisms|Rep: DNA replication licensing
factor, putative - Plasmodium falciparum (isolate 3D7)
Length = 1465
Score = 130 bits (313), Expect = 2e-28
Identities = 76/182 (41%), Positives = 110/182 (60%), Gaps = 9/182 (4%)
Query: 373 NVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALM 432
++ +VGDP T KSQLLK+V +++ V SG + AGLT A +++ SF ++E+GAL+
Sbjct: 1032 HLLLVGDPGTGKSQLLKEVQKLSNICVNVSGMFCTTAGLTCAAIKEGNSF--MLESGALV 1089
Query: 433 LADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAAN-----P 487
LADNGVCCIDEF M ++ AIHEAMEQ +IS+AK G+ LN R +I+ A+N
Sbjct: 1090 LADNGVCCIDEFCLMKNENKNAIHEAMEQLSISVAKGGIVDKLNCRCTIIGASNFEINKE 1149
Query: 488 IGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDC 547
+ G S + LS ++SRFDL ++I E + +DY IA I+ ++ D
Sbjct: 1150 VKGNLSNYDSKVIIINLSYALLSRFDL--VVIAEDNSQIDYKIADYILSQDVEVKKGLDN 1207
Query: 548 VY 549
Y
Sbjct: 1208 EY 1209
>UniRef50_A5K611 Cluster: DNA replication licensing factor, putative;
n=1; Plasmodium vivax|Rep: DNA replication licensing
factor, putative - Plasmodium vivax
Length = 1310
Score = 126 bits (305), Expect = 2e-27
Identities = 72/170 (42%), Positives = 106/170 (62%), Gaps = 10/170 (5%)
Query: 373 NVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALM 432
++ +VGDP T KSQLLK+V +I+ + SG + AGLT A ++ E +F++E+GAL+
Sbjct: 882 HLLLVGDPGTGKSQLLKEVQKISNICMNVSGMFCTTAGLTCAAIK--EGNNFMLESGALV 939
Query: 433 LADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAAN-----P 487
LADNGVCCIDEF M ++ AIHEAMEQ TIS+AK G+ LN R +I+ A+N
Sbjct: 940 LADNGVCCIDEFCLMKNENKNAIHEAMEQLTISVAKGGIVDKLNCRCTIIGASNFELHKT 999
Query: 488 IGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDES---SEMVDYAIARKI 534
+ G + + LS ++SRFD+ I D + S++ DY +A+ +
Sbjct: 1000 VKGNLSSCDNKALIINLSYALLSRFDMVVITEDNNEIDSKIADYVLAQDV 1049
>UniRef50_Q7RKP3 Cluster: DNA replication licensing factor of the
MCM family-related; n=3; Plasmodium (Vinckeia)|Rep: DNA
replication licensing factor of the MCM family-related -
Plasmodium yoelii yoelii
Length = 1229
Score = 125 bits (302), Expect = 4e-27
Identities = 70/164 (42%), Positives = 104/164 (63%), Gaps = 9/164 (5%)
Query: 373 NVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALM 432
++ +VG+P T KSQLLK++ +T SG + AGLT A ++ E +F++E+GAL+
Sbjct: 822 HLLLVGNPGTGKSQLLKEIKNLTNICTNVSGMFCTTAGLTCAAIK--EGNNFMLESGALV 879
Query: 433 LADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAAN-----P 487
LADNGVCCIDEF M ++ AIHEAMEQ +IS+AKAG+ LN R +I+ A+N
Sbjct: 880 LADNGVCCIDEFCLMKTENKNAIHEAMEQLSISIAKAGIVDKLNCRCTIIGASNFEIHKN 939
Query: 488 IGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIA 531
+ G D+ + + LS ++SRFDL ++I E ++ D +A
Sbjct: 940 MNGTIDKCQDQVLIINLSYALLSRFDL--VVITEDNDETDARVA 981
>UniRef50_Q4XQK3 Cluster: Minichromosome maintenance protein,
putative; n=2; Plasmodium chabaudi|Rep: Minichromosome
maintenance protein, putative - Plasmodium chabaudi
Length = 564
Score = 125 bits (302), Expect = 4e-27
Identities = 62/170 (36%), Positives = 103/170 (60%), Gaps = 1/170 (0%)
Query: 319 VYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR-GDINVCIV 377
+ + + +N + L++S P + N +K G+LL L GG G R G+ ++ ++
Sbjct: 393 IKDFEKYKNKFYLLVSSFCPRVIMNYYIKAGLLLSLLGGKTIYDQFGEIKRRGNTHLLLI 452
Query: 378 GDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNG 437
GDP KS++L+ +S I ++++ ++S GLTA V+D + ++ +E GAL+L+D G
Sbjct: 453 GDPGLGKSRILQYISNIIEKSLFICSTSTSINGLTACAVKDSTNNEYSLEGGALVLSDKG 512
Query: 438 VCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP 487
VCCIDE DK+ DQ + E ME Q I+++KAG+ L R +I+AA+NP
Sbjct: 513 VCCIDELDKVSLKDQQSFLECMESQCINISKAGIVCNLKTRCTIIAASNP 562
>UniRef50_Q5V814 Cluster: MCM / cell division control protein 21;
n=1; Haloarcula marismortui|Rep: MCM / cell division
control protein 21 - Haloarcula marismortui
(Halobacterium marismortui)
Length = 649
Score = 122 bits (293), Expect = 5e-26
Identities = 95/331 (28%), Positives = 151/331 (45%), Gaps = 27/331 (8%)
Query: 343 NNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTS 402
+ +V RG++L L +G+ RGD++V + GDP T KS L K + + PR+ + S
Sbjct: 298 DRQVVRGLVLQLVSASTFDGPDGSHYRGDVHVLLPGDPGTGKSVLAKWAAAVAPRSAFAS 357
Query: 403 GKASSAAGLTAAVVRDEESFD-FVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQ 461
G+ S GLTAA V+D+ S F IE G L+ A G+ +DE DK +H A+
Sbjct: 358 GERVSGPGLTAAAVKDDFSDGGFSIEPGVLVRAHEGIAVVDELDKAGDDAIEKMHSALAD 417
Query: 462 QTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFIL--- 518
Q + L+ G TL A +L NP+GG + +SL + ++ P++SRFDL +
Sbjct: 418 QILPLSLGGQSMTLPAECGLLGVCNPLGGHFAGDESLVDALGINSPLLSRFDLIMQMRSK 477
Query: 519 -----IDESSEMVDYAIARKIVD-----LHCNKEESYDCVYSRDDLLRYIAFARSFKP-- 566
+ E +E + + + D L ++ D V S D + AR P
Sbjct: 478 QDREHVRELAESMIRTWSASLKDATGQALDTADADTIDPVLSMDQYRAVLLRARQLHPTP 537
Query: 567 ----VIT------EEAGKLLVEYYXXXXXXXXXXXXX-XWRITVRQLESMVRLAEGVAKM 615
VI EE L E Y +T R+L + R+A+ A+
Sbjct: 538 ANDRVIEALAAWFEEQKMALPERYRDALADADGQYHGPPVPVTARKLGAARRVAQAAARA 597
Query: 616 HCSGHVTPAHVHEAYRLLNKSIIRVEQPDIH 646
+ +T A V A L+++S+ ++ P +H
Sbjct: 598 NLREEITMADVEVAKELVSRSLADLDIPIVH 628
>UniRef50_Q5JIT1 Cluster: DNA replication licensing factor, MCM2/3/5
family; n=3; Thermococcus kodakarensis KOD1|Rep: DNA
replication licensing factor, MCM2/3/5 family -
Pyrococcus kodakaraensis (Thermococcus kodakaraensis)
Length = 1157
Score = 121 bits (292), Expect = 7e-26
Identities = 71/191 (37%), Positives = 109/191 (57%), Gaps = 4/191 (2%)
Query: 447 MDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSP 506
++P H + TIS++KAG+ ATLN+RT+++AAANP GR++R KSL + + L P
Sbjct: 873 VEPHHLFVSHGLVLHNTISISKAGITATLNSRTTVIAAANPKFGRFNRHKSLPEQLDLPP 932
Query: 507 PIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFAR-SFK 565
++SRFDL F+L+DE E VD +IA I+ + + E+ D L +YIA+AR +
Sbjct: 933 TLLSRFDLIFLLLDEPDEKVDASIAEHILKVRRGEAEAVTPKIPYDLLKKYIAYARKNVH 992
Query: 566 PVITEEAGKLLVEYYXXXXXXXXXXXXXXWR---ITVRQLESMVRLAEGVAKMHCSGHVT 622
PV++ EA + + YY + IT RQLE+++RL+E A+M S VT
Sbjct: 993 PVLSREAMEEIKRYYVKMRKGLRRGDEDGVQPIPITARQLEALIRLSEAHARMRLSETVT 1052
Query: 623 PAHVHEAYRLL 633
A ++
Sbjct: 1053 REDARAAIEII 1063
Score = 112 bits (269), Expect = 4e-23
Identities = 110/394 (27%), Positives = 190/394 (48%), Gaps = 42/394 (10%)
Query: 25 FQDFLEEFKED--NEIKYEKHAKELLK--PELSTLEVSFDDVEKYNQNLATTIIEEYYRI 80
F FL E+ +D NE+ Y K+LL P+ S L + + + ++ LA ++
Sbjct: 10 FAKFLREYVDDEGNEV-YINRLKDLLTVTPKRS-LAIDWAHLNSFDPELADELLNNPEEA 67
Query: 81 YPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQI 140
AI + L E + + + K + F ++P V+EL + I LI++ G I
Sbjct: 68 IASAEDAIQ---IVLREPPLLVEREFK-VHARFYNLPKTLLVKELGSEHINKLIQVEGII 123
Query: 141 VRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRG 200
R V P + + F + C N + +R + + K D R E + R
Sbjct: 124 TRVSEVKPFVEKAVF--VCRDCGNEMVRLQRPYE-NLVKPAKCDACGSRNIELDVDKSRF 180
Query: 201 CIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQM 260
+S + + ES++ G F I++ D+ ++PG R +T ++ E +
Sbjct: 181 LNFQSFRL---QDRPESLKGGQMPRFVDA-ILLDDLVDAALPGDRVLVTGVLRVILEQRE 236
Query: 261 EGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVY 320
+ K L V ++ +S+ E+ +++ ED +K +
Sbjct: 237 KRPIFKKILEVNH-----------IEQLSK-----EIEELEISPEDEQK---------IR 271
Query: 321 EMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDP 380
E+++ +++ + ++ S+ P+I G+ VK+G+ L LFGGV +T +GT LRG+ +V +VGDP
Sbjct: 272 ELAKRKDIVDAIVDSIAPAIWGHRIVKKGIALALFGGVQRTLPDGTKLRGESHVLLVGDP 331
Query: 381 STAKSQLLKQVSEITPRAVYTSGKASSAAGLTAA 414
AKSQLL+ V+ + PRA+YTSGK+SSAAGL A
Sbjct: 332 GVAKSQLLRYVANLAPRAIYTSGKSSSAAGLCVA 365
Score = 66.5 bits (155), Expect = 3e-09
Identities = 32/52 (61%), Positives = 39/52 (75%)
Query: 412 TAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQT 463
TAA VRDE + +V+EAG L+LAD G IDEFDKM D+ AIHEA+EQQ+
Sbjct: 503 TAAAVRDEFTGSWVLEAGVLVLADGGFALIDEFDKMSDRDRSAIHEALEQQS 554
>UniRef50_Q9VF30 Cluster: DNA replication licensing factor REC; n=3;
Sophophora|Rep: DNA replication licensing factor REC -
Drosophila melanogaster (Fruit fly)
Length = 885
Score = 119 bits (286), Expect = 4e-25
Identities = 67/233 (28%), Positives = 127/233 (54%), Gaps = 11/233 (4%)
Query: 307 MRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGT 366
++++ ++++ + + ++ + N + L+ S+ P ++G+ K LL L GG T
Sbjct: 409 IKREFSERDLEAIVMINAEPNSFKLLVQSIAPEVYGHELPKAACLLSLLGGKGAETEA-- 466
Query: 367 TLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVI 426
INV +VGDP K+++L+ ++I R + SGK + + V + V+
Sbjct: 467 -----INVLLVGDPGIGKTKILQSCAQIAERGAHVSGKRGAQSAQQLGVTFAGRN-KRVL 520
Query: 427 EAGALMLADNGV-CCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAA 485
+AG+LM+A G C +D+ DK+ Q + + ++ + ++L AG A+ A+ S++A A
Sbjct: 521 QAGSLMMASGGGHCTLDDVDKL-ASKQAVLLQCLQSEEVNLPLAGAFASFPAQPSVIACA 579
Query: 486 NPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
NP G+YD + L QN+ +SP ++ F L +IL+D+ SE D ++ + LH
Sbjct: 580 NPQRGQYDEGRYLLQNINISPSLLREFHLVYILLDKPSER-DMSLTAHVRALH 631
Score = 39.9 bits (89), Expect = 0.26
Identities = 21/83 (25%), Positives = 42/83 (50%), Gaps = 1/83 (1%)
Query: 556 RYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAK 614
+++++AR PV+ E+A ++ Y+ +I QL +++ L++ A+
Sbjct: 710 KFLSYARQELNPVLNEDASNAVLRYFLELKGSCNLDEDVSSQIGAGQLLAIIHLSQARAR 769
Query: 615 MHCSGHVTPAHVHEAYRLLNKSI 637
+ S V+P HV + LL +SI
Sbjct: 770 LDLSHVVSPQHVRDVIALLTESI 792
>UniRef50_Q7SHD5 Cluster: Putative uncharacterized protein
NCU01871.1; n=2; Neurospora crassa|Rep: Putative
uncharacterized protein NCU01871.1 - Neurospora crassa
Length = 510
Score = 117 bits (282), Expect = 1e-24
Identities = 54/121 (44%), Positives = 78/121 (64%)
Query: 318 KVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIV 377
++ + + N Y L S+ P I+G+ +VK+ +LL+L GG+ K +G R DIN+C++
Sbjct: 366 RIAKFQQTGNTYEYLAKSIAPEIYGHLDVKKALLLLLVGGITKEVGDGMKTRSDINICLM 425
Query: 378 GDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNG 437
GDP AKSQLLK +S++ PR VYTSG+ SS GLTA V+RD + + V+E G NG
Sbjct: 426 GDPGVAKSQLLKYISKVAPRGVYTSGRGSSGVGLTATVMRDPVTDEMVLEGGKREREKNG 485
Query: 438 V 438
V
Sbjct: 486 V 486
>UniRef50_Q4XU98 Cluster: DNA replication licensing factor,
putative; n=4; Plasmodium chabaudi|Rep: DNA replication
licensing factor, putative - Plasmodium chabaudi
Length = 915
Score = 115 bits (277), Expect = 4e-24
Identities = 58/129 (44%), Positives = 86/129 (66%), Gaps = 2/129 (1%)
Query: 358 VAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVR 417
+ + +++ R ++ +VG+P T KSQLLK++ +T SG + AGLT A ++
Sbjct: 763 IKEVSVDNYHKRSLCHLLLVGNPGTGKSQLLKEIKNLTNICTNVSGMFCTTAGLTCAAIK 822
Query: 418 DEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNA 477
E +F++E+GAL+LADNGVCCIDEF M ++ AIHEAMEQ +IS+AKAG+ LN
Sbjct: 823 --EGNNFMLESGALVLADNGVCCIDEFCLMKTENKNAIHEAMEQLSISIAKAGIVDKLNC 880
Query: 478 RTSILAAAN 486
R +I+ A+N
Sbjct: 881 RCTIIGASN 889
>UniRef50_Q0UQC3 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 215
Score = 103 bits (246), Expect = 2e-20
Identities = 50/82 (60%), Positives = 63/82 (76%)
Query: 376 IVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLAD 435
+VGDPSTAKSQLL+ V P A+ T+G+ SS GLTAAV +D+E+ + +EAGA++LAD
Sbjct: 1 MVGDPSTAKSQLLRFVLNTAPLAIATTGRGSSGVGLTAAVTQDKETGERRLEAGAMVLAD 60
Query: 436 NGVCCIDEFDKMDPGDQVAIHE 457
GV CIDEFDKM D+VAIHE
Sbjct: 61 RGVVCIDEFDKMSDVDRVAIHE 82
>UniRef50_A5DWW3 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 473
Score = 98.7 bits (235), Expect = 5e-19
Identities = 43/92 (46%), Positives = 65/92 (70%)
Query: 447 MDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSP 506
M D+VAIHE MEQQT+++AKAG+ +LNAR S++AAANP+ G+YD K +N+AL
Sbjct: 1 MSDSDRVAIHEVMEQQTVTIAKAGIHTSLNARCSVIAAANPVFGQYDVHKDPHKNIALPD 60
Query: 507 PIMSRFDLFFILIDESSEMVDYAIARKIVDLH 538
++SRFDL F++ D+ + D I+ ++ +H
Sbjct: 61 SLLSRFDLLFVVTDDVNPTKDRVISEHVLRMH 92
>UniRef50_Q8GSB2 Cluster: MCM5-like; n=19; Magnoliophyta|Rep:
MCM5-like - Arabidopsis thaliana (Mouse-ear cress)
Length = 86
Score = 92.3 bits (219), Expect = 5e-17
Identities = 46/84 (54%), Positives = 57/84 (67%)
Query: 457 EAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFF 516
EAMEQQTIS+AKAG+ LN+RTS+LAAANP GRYD K+ Q N+ L I+SRFDL F
Sbjct: 1 EAMEQQTISIAKAGITTVLNSRTSVLAAANPPSGRYDDLKTAQDNIDLQTTILSRFDLIF 60
Query: 517 ILIDESSEMVDYAIARKIVDLHCN 540
I+ D D IA I+ +H +
Sbjct: 61 IVKDIRKYSQDKEIASHIIRVHAS 84
>UniRef50_A7TAU8 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 107
Score = 85.0 bits (201), Expect = 7e-15
Identities = 41/84 (48%), Positives = 63/84 (75%), Gaps = 3/84 (3%)
Query: 716 SGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLRGT 775
SG+ +S VV+WYL ++ Q +IE+E+EL E+K LV+KV+DRL+++D VI+ L +
Sbjct: 26 SGLRRSRVVNWYLGEI--QSEIETEEELAEKKMLVDKVLDRLIHNDGVILELKSWKESDK 83
Query: 776 QKSSEQD-IEDDPLLVVHPNYVVD 798
+K E+D E+DPLLVVHPNY+++
Sbjct: 84 EKEGEKDEEEEDPLLVVHPNYLLE 107
>UniRef50_Q4SLL7 Cluster: Chromosome 15 SCAF14556, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 15
SCAF14556, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 934
Score = 83.0 bits (196), Expect = 3e-14
Identities = 43/116 (37%), Positives = 73/116 (62%), Gaps = 2/116 (1%)
Query: 465 SLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSE 524
+L + G+ LNART++LAAANP+ +++ K+ +N+ L ++SRFDL F+++D E
Sbjct: 643 ALHRQGIICQLNARTAVLAAANPVESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDE 702
Query: 525 MVDYAIARKIVDLHCNKEESYDCVYSRDDLLR-YIAFARSF-KPVITEEAGKLLVE 578
D +A +V L+ EE + + +LR YIA+AR++ P ++EEA + L+E
Sbjct: 703 AYDRRLAHHLVALYYQSEEQMEEEFLDMAVLRDYIAYARTYISPRLSEEASQALIE 758
Score = 59.3 bits (137), Expect = 4e-07
Identities = 58/238 (24%), Positives = 102/238 (42%), Gaps = 24/238 (10%)
Query: 13 VKDEVGIRC-QKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71
+K G+ C Q+ Q F++ ++E + L +L + V D V N
Sbjct: 181 LKGNRGLFCLQRFLQRFVDPTSSEDENAGLDLNEPLYMQKLEEISVVGDPVLNVNCLHVR 240
Query: 72 TIIEEYYR-IYPFLNRAILNYILSLAETGMKK---DLQDKECYVSFVDVPTRHKVRELTT 127
+ E YR + + I + +++ E ++ + + + V + +R L
Sbjct: 241 SFDAELYRQLICYPQEVIPTFDMAVNELFFERFPDSILEYQIQVRPYNALKTKNMRSLNP 300
Query: 128 AKIGTLIRISGQIVRTHPVHPELVQGTF------YTI-----------PTICRNPVCANR 170
I LI I+G ++RT + PE+ + F +T P +CR+ C N
Sbjct: 301 EDIDQLITINGMVIRTSQLIPEMQEAFFQCQVCAFTTRVEVDRGRIAEPAVCRH--CNNT 358
Query: 171 RRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
L ++SVF D Q ++IQE+ ++P G P + V + V+ VQ GDR + TG
Sbjct: 359 HSLALIHNRSVFSDKQMVKIQESPEDMPAGQTPHTTIVYAHNDLVDKVQPGDRVNITG 416
>UniRef50_Q8TWB5 Cluster: Predicted ATPase involved in replication
control, Cdc46/Mcm family; n=1; Methanopyrus
kandleri|Rep: Predicted ATPase involved in replication
control, Cdc46/Mcm family - Methanopyrus kandleri
Length = 506
Score = 78.2 bits (184), Expect = 8e-13
Identities = 87/299 (29%), Positives = 131/299 (43%), Gaps = 37/299 (12%)
Query: 342 GNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYT 401
G EV + + L LF V K + ++V + G P L + + PR VY
Sbjct: 217 GAEEVGKMLALQLFSCVGKNSER-------LHVLLAGYPVVCSEILHHVLDHLAPRGVYV 269
Query: 402 SGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQ 461
+ + LTA + D + + AGA +LAD G+ +D + + A+ EAM++
Sbjct: 270 DLRRTELTDLTAVLKEDR---GWALRAGAAVLADGGILAVDHLEGAPEPHRWALMEAMDK 326
Query: 462 QTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDE 521
T+++ G+ LNAR ++LAA NP G ++ + + + L +S FDL
Sbjct: 327 GTVTV--DGI--ALNARCAVLAAINP-GEQWPSDPPIAR-IDLDQDFLSHFDL------- 373
Query: 522 SSEMVDYAIARKIVDLHCNKEESYDC-VYSRDDLLRYIAFA--RSFKPVITEEAGKLLVE 578
IA VD + E D V S L RY+ +A KP +TEEA K L
Sbjct: 374 --------IAFLGVDPRPGEPEEQDTEVPSYTLLRRYLLYAIREHPKPELTEEARKRLEH 425
Query: 579 YYXXXXXXXXXXXXX---XWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN 634
+Y +T RQLES+ RLA+ A+M S V P V A L++
Sbjct: 426 WYETRREEVEERLGMGLPTLPVTRRQLESVERLAKAHARMRLSDDVEPEDVDIAAELVD 484
>UniRef50_Q18E84 Cluster: ATP-dependent DNA helicase; n=1;
Haloquadratum walsbyi DSM 16790|Rep: ATP-dependent DNA
helicase - Haloquadratum walsbyi (strain DSM 16790)
Length = 2216
Score = 77.4 bits (182), Expect = 1e-12
Identities = 54/182 (29%), Positives = 94/182 (51%), Gaps = 24/182 (13%)
Query: 463 TISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDES 522
+IS++KAG+ ATL +R S+L AANP GR+D+ + + + + L P ++SRFDL F + DE
Sbjct: 1929 SISVSKAGINATLKSRCSLLGAANPKYGRFDQYEPIGEQIDLEPALISRFDLIFTVTDEP 1988
Query: 523 SEMVDYAIARKIV------DLHCNKEESYDCVYSRDD----------------LLRYIAF 560
D +A I+ +LH K + ++ + L +Y+A+
Sbjct: 1989 DPDADAKLADHIINTNYAGELHTQKANIPNSEFTDGEVESATAEVTPTIDAELLRKYVAY 2048
Query: 561 A-RSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSG 619
A R+ P +T++A ++ ++Y +T R+LE++VRL+E A++ S
Sbjct: 2049 ARRNCYPTMTDDAQDVIRKFYVDFRAKGADDDAPV-PVTARKLEALVRLSEASARLRLSD 2107
Query: 620 HV 621
V
Sbjct: 2108 TV 2109
Score = 70.5 bits (165), Expect = 2e-10
Identities = 37/113 (32%), Positives = 66/113 (58%), Gaps = 6/113 (5%)
Query: 311 MTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRG 370
+TD++ ++ E+S D ++Y ++ S+ PSI+G +E K ++L LF GV K +G+ +RG
Sbjct: 262 ITDEDVAEIVELSNDPDIYEKMVESVAPSIYGYDEEKLAMILQLFSGVTKHLPDGSRIRG 321
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD 423
D+++ ++GDP T K VS T A+ GK ++ L + + D + D
Sbjct: 322 DLHMLLIGDPGTGKC-----VSGETDIAL-VEGKTATIGELVESALTDPKPVD 368
Score = 52.4 bits (120), Expect = 5e-05
Identities = 52/199 (26%), Positives = 86/199 (43%), Gaps = 28/199 (14%)
Query: 51 ELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECY 110
E +L + + D+ ++ LA E YR P R L L + + D++ +
Sbjct: 37 EKRSLYIDYHDLYAFDVELA-----EDYRREPDQLREYAEEALRLYD--LPADVKLGRAH 89
Query: 111 VSFVDVPTRHKVRELTTAK--IGTLIRISGQIVRTHPVHPELVQGTF------------- 155
V +P +R + IG LI + G + + V P++ + F
Sbjct: 90 VRMRSLPDTVDIRNIRVHDDHIGHLIAVQGIVRKATDVRPKITEAAFECQRCGTMTYIPQ 149
Query: 156 ----YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILR 211
+ P C+ C + F +D D+S F+D QK+R+QE+ L G P+S++V L
Sbjct: 150 SDSGFQEPHECQG--CERQGPFDVDFDQSEFIDAQKVRVQESPEGLRGGETPQSIDVDLE 207
Query: 212 AEAVESVQAGDRYDFTGTL 230
+A +V AGD TG L
Sbjct: 208 DDATGAVTAGDHVTTTGVL 226
Score = 42.7 bits (96), Expect = 0.037
Identities = 20/38 (52%), Positives = 27/38 (71%), Gaps = 2/38 (5%)
Query: 412 TAAVVRDE--ESFDFVIEAGALMLADNGVCCIDEFDKM 447
TAA VRD+ + + +EAGAL+LAD G+ +DE DKM
Sbjct: 1093 TAAAVRDDFGDGQQWTLEAGALVLADKGIAAVDELDKM 1130
Score = 37.1 bits (82), Expect = 1.9
Identities = 16/27 (59%), Positives = 21/27 (77%)
Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGL 411
S +L+ + I PR+VYTSGK SS+AGL
Sbjct: 545 SAMLQYIRNIAPRSVYTSGKGSSSAGL 571
>UniRef50_Q4SRE5 Cluster: Chromosome undetermined SCAF14527, whole
genome shotgun sequence; n=3; Tetraodontidae|Rep:
Chromosome undetermined SCAF14527, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 369
Score = 77.0 bits (181), Expect = 2e-12
Identities = 37/66 (56%), Positives = 50/66 (75%), Gaps = 2/66 (3%)
Query: 405 ASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTI 464
A + GLT A V+D D+ +EAGAL+LAD G+CCIDEF + ++++IHEAMEQQ+I
Sbjct: 306 ACVSEGLTVAAVKDGN--DWHLEAGALVLADGGLCCIDEFSSIKEHERISIHEAMEQQSI 363
Query: 465 SLAKAG 470
S+AKAG
Sbjct: 364 SVAKAG 369
Score = 75.4 bits (177), Expect = 6e-12
Identities = 40/113 (35%), Positives = 64/113 (56%), Gaps = 3/113 (2%)
Query: 298 PTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGG 357
PT + +D++++ D W N ++ SL P + G VK V L+L GG
Sbjct: 161 PTSAVALKDIQEEYEDF-WKSYQHFPLSGR--NFILLSLCPQVFGMYVVKLAVALVLAGG 217
Query: 358 VAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAG 410
V + GT +RG+ ++ +VGDP T KSQLLK +++ PR++ T+G S++AG
Sbjct: 218 VERRDASGTKVRGECHMLLVGDPGTGKSQLLKYAAKVIPRSILTTGIGSTSAG 270
Score = 44.4 bits (100), Expect = 0.012
Identities = 25/72 (34%), Positives = 37/72 (51%), Gaps = 3/72 (4%)
Query: 162 CRNPVCANRRRFML---DADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESV 218
C NP RF D++ D+Q+I+IQE L G IPRS+ V+L + V+S
Sbjct: 57 CPNPAGCTSTRFSSLSRDSEPGACKDYQEIKIQEQVQRLSVGKIPRSMVVVLEDDLVDSC 116
Query: 219 QAGDRYDFTGTL 230
++GD G +
Sbjct: 117 KSGDDVTVYGVM 128
>UniRef50_A7QHD5 Cluster: Chromosome chr2 scaffold_97, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr2 scaffold_97, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 182
Score = 76.6 bits (180), Expect = 2e-12
Identities = 44/131 (33%), Positives = 66/131 (50%), Gaps = 2/131 (1%)
Query: 330 NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLK 389
N ++ + P + G VK + L L GGV T +RG ++ +VGDP S+++
Sbjct: 54 NAILRGICPQVFGLFIVKLAIALTLIGGVQHVDASRTKVRGKSHLLLVGDPGNFFSEIIL 113
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449
+ + P V G + E ++++EA AL+L D G+CCIDEFD M
Sbjct: 114 KSLFVWP--VDLLGSVCFLNFIARLTTFKEFLGEWMLEARALVLVDGGLCCIDEFDSMRE 171
Query: 450 GDQVAIHEAME 460
D+ IHEAME
Sbjct: 172 HDRATIHEAME 182
>UniRef50_A5AUI5 Cluster: Putative uncharacterized protein; n=1;
Vitis vinifera|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 687
Score = 75.8 bits (178), Expect = 4e-12
Identities = 37/89 (41%), Positives = 54/89 (60%)
Query: 330 NNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLK 389
N ++ + P + G VK V L L GGV GT +RG+ ++ +VGDP T KSQ LK
Sbjct: 593 NAILRGICPQVFGLFTVKLAVALTLIGGVQHVDASGTKVRGESHLLLVGDPGTGKSQFLK 652
Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRD 418
++++ R+V T+G S++AGLT VRD
Sbjct: 653 FAAKLSNRSVITTGFGSTSAGLTVTAVRD 681
>UniRef50_Q4SRE8 Cluster: Chromosome undetermined SCAF14527, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF14527,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 453
Score = 74.1 bits (174), Expect = 1e-11
Identities = 47/141 (33%), Positives = 75/141 (53%), Gaps = 5/141 (3%)
Query: 475 LNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKI 534
LN RTSILAA NP G ++ L +VAL+ P++SRFDL +L+D S D I+ I
Sbjct: 297 LNTRTSILAATNP-KGTLSPSEPLAVSVALASPLLSRFDLVLVLMDNRSTEWDRVISSFI 355
Query: 535 VDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXX 594
++ S D +++ + + Y + + +P ++E+A +L YY
Sbjct: 356 LEDRELCSASAD-LWTLEKMRAYFSLIKQLQPQMSEDANSILTRYYQRQRQTEGRSAA-- 412
Query: 595 WRITVRQLESMVRLAEGVAKM 615
R T+R LES+ RLAE +++
Sbjct: 413 -RTTIRMLESLSRLAEAHSRL 432
>UniRef50_Q380P7 Cluster: ENSANGP00000029332; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000029332 - Anopheles gambiae
str. PEST
Length = 469
Score = 71.3 bits (167), Expect = 9e-11
Identities = 42/102 (41%), Positives = 57/102 (55%), Gaps = 2/102 (1%)
Query: 315 EWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTI--EGTTLRGDI 372
EW +V + + L+ S+ P+I G VK + L L + + T+RG
Sbjct: 177 EWQEVLREIGELAARDLLVQSIAPAIRGMYPVKLAIALALASCTERVGDGEQQATVRGHS 236
Query: 373 NVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAA 414
++ +VGDP AKSQLLK SEI RAVYT+G S+AGLTAA
Sbjct: 237 HLLLVGDPGLAKSQLLKYASEIASRAVYTTGMGCSSAGLTAA 278
Score = 65.7 bits (153), Expect = 5e-09
Identities = 55/188 (29%), Positives = 90/188 (47%), Gaps = 16/188 (8%)
Query: 462 QTISLAKAGVRATLNARTSILAAANP--IGGRYDRAKSLQQNVALSPPIMSRFDLFFIL- 518
QTIS+AKAG+ L+ R +LAA NP + D +N+ + P++SRFD+ IL
Sbjct: 280 QTISVAKAGMVCKLSTRCVVLAATNPKNLYTMSDGLGKSAENIGIGGPLLSRFDMVMILK 339
Query: 519 ----IDESSEMVDYAIARKIVD--LHCNKEES--YDCV--YSRDDLLRYIAFARSFKPVI 568
D +++ ++ +A+ ++D C + E D V + + L + A + F P +
Sbjct: 340 DVRAADWDADIANHLLAQALLDEERECFEGEGNRTDRVAHWELEKLQLHFAAIKDFHPRV 399
Query: 569 TEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHE 628
+ EA +L YY R TVR L+S+ RLA+ A++ VTP
Sbjct: 400 SPEANVILGAYYKACRSDPYRDPT---RTTVRLLDSLFRLAQAHARLLLRNEVTPIDAIT 456
Query: 629 AYRLLNKS 636
+L+ S
Sbjct: 457 IIQLMEAS 464
>UniRef50_Q45NK0 Cluster: Mini-chromosome maintenance protein; n=1;
Medicago sativa|Rep: Mini-chromosome maintenance protein
- Medicago sativa (Alfalfa)
Length = 199
Score = 64.5 bits (150), Expect = 1e-08
Identities = 51/199 (25%), Positives = 91/199 (45%), Gaps = 21/199 (10%)
Query: 621 VTPAHVHEAYRLLNKSIIRVEQPDIHLDE--DEPQCEPSMDVDQDEPN------------ 666
V P HV A +LL SIIRV+ +I L E D+ E + D ++ N
Sbjct: 1 VQPRHVRLAVKLLQTSIIRVKSSEIDLSEFQDQDMDEEAGSDDGNDNNDADGQAGNSTAQ 60
Query: 667 ---GTAETPSNGDSAPKKKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHKSAV 723
GT E P+NG + +KK ++ E ++ ++ LV+ +R+ +GM + +
Sbjct: 61 EAAGTNEKPANGSNPQRKKSTVTDEYFQRITKALVMRLRQHEETVMQEGSGLAGMKQRDL 120
Query: 724 VSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLRGTQ----KSS 779
+ WY++Q + S +E + ++ +I+ L+ + +I + ++ + S
Sbjct: 121 IKWYVDQQNEKNNYSSVEEAKVEISQIKAIIEILIRREGHLIVIDDGRQAASEAAGAEQS 180
Query: 780 EQDIEDDPLLVVHPNYVVD 798
E +D L V PNYV D
Sbjct: 181 ESAARNDRTLAVAPNYVGD 199
>UniRef50_Q2HFB8 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 137
Score = 62.5 bits (145), Expect = 4e-08
Identities = 29/66 (43%), Positives = 45/66 (68%), Gaps = 1/66 (1%)
Query: 480 SILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHC 539
SILA+ANPIG RY+ S+ QN+ L P ++SRFDL ++++D E D +AR ++ ++
Sbjct: 49 SILASANPIGSRYNPDMSVPQNIDLPPTLLSRFDLVYLILDRVDEKADQRLARHLLSMYL 108
Query: 540 -NKEES 544
+K ES
Sbjct: 109 EDKPES 114
Score = 57.6 bits (133), Expect = 1e-06
Identities = 27/55 (49%), Positives = 39/55 (70%), Gaps = 2/55 (3%)
Query: 344 NEVKRGVLLMLFGGVAKTTIEGTT--LRGDINVCIVGDPSTAKSQLLKQVSEITP 396
++VK+G+LL +FGG KT +G + RGDINV + GDPST+KSQ+L ++ P
Sbjct: 2 DDVKKGILLQMFGGTNKTFEKGASPKYRGDINVLLCGDPSTSKSQILSILASANP 56
>UniRef50_Q60275 Cluster: Uncharacterized MCM-type protein MJECL13;
n=1; Methanocaldococcus jannaschii|Rep: Uncharacterized
MCM-type protein MJECL13 - Methanococcus jannaschii
Length = 602
Score = 58.8 bits (136), Expect = 5e-07
Identities = 64/280 (22%), Positives = 116/280 (41%), Gaps = 26/280 (9%)
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429
G IN+ +V + K+ +LK++ I T R F G
Sbjct: 307 GKINILLVTEVGIDKTAILKRIGNIPGNNFINIAALKEEELATPYDKRSNILGKFYTVCG 366
Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489
++ GV CID+F++ + + EA E+ ++ K G + A S L A P
Sbjct: 367 GVIPRTLGVLCIDDFNENNKLS-TKLSEAFERNVLTTNK-GSFYCVPAECSFLCACYPKT 424
Query: 490 G--RYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKE----E 543
++D+ KS+ + + +S ++ FDL F + D + D +A+ I + N + E
Sbjct: 425 KFRKFDQKKSIIKQIGISSILLKNFDLIFPIRDIPDKDRDEEVAKYIFLKYINSDNEEIE 484
Query: 544 SYDCVY----------SRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXX 593
YD V+ + L +Y+ ++R P IT+E + + +Y
Sbjct: 485 GYDYVFVDVGGEKIKIDFEFLKKYVVYSRQITPKITDEVIEKISNWYDEMRKNHY----- 539
Query: 594 XWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLL 633
IT +QL ++++L+ VA+ V V EA ++
Sbjct: 540 ---ITAKQLNTVIKLSIAVARAKLKECVDEDDVKEAIDII 576
>UniRef50_A2YAR1 Cluster: Putative uncharacterized protein; n=1;
Oryza sativa (indica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. indica
(Rice)
Length = 470
Score = 54.0 bits (124), Expect = 2e-05
Identities = 31/79 (39%), Positives = 42/79 (53%), Gaps = 2/79 (2%)
Query: 146 VHPELVQGTFYTIPTICRNPVC--ANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIP 203
VHPEL G T+P C++ F L D D+Q+I+IQE L G IP
Sbjct: 179 VHPELEAGNRITLPASCKSKSAKGCGGANFQLIEDSITCHDYQEIKIQENIQLLGVGSIP 238
Query: 204 RSLEVILRAEAVESVQAGD 222
RS+ +IL + V+ V+AGD
Sbjct: 239 RSMPIILMDDLVDIVKAGD 257
>UniRef50_A0DCN1 Cluster: Chromosome undetermined scaffold_45, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_45,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 803
Score = 54.0 bits (124), Expect = 2e-05
Identities = 50/238 (21%), Positives = 98/238 (41%), Gaps = 27/238 (11%)
Query: 22 QKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIY 81
+K F FL+E++ Y +L + + L + + ++N +L +I I
Sbjct: 78 EKQFDRFLKEYRSGGMEYYMSQLNQLNETDQFILNIDGRHLLEFNNHLYQQLIHYPAEII 137
Query: 82 PFLNRAILNYI----LSL-AETGMKKD---LQDKECYVSFVDVPTRHKVRELTTAKIGTL 133
P + + LSL A +++ L + + +++ +VREL I L
Sbjct: 138 PIFDTVVQKVFYDDFLSLKARNEQEREEFRLYAQRLLIGIINLERNVQVRELNPKDINKL 197
Query: 134 IRISGQIVRTHPVHPELVQGTFYTI-----------------PTICRNPVCANRRRFMLD 176
I ++G ++R ++P++ Q TF P C+ C ++ + L
Sbjct: 198 ISVTGIVIRCSELYPDMKQATFKCTKCGHIVGVNIERGRVEEPISCQR--CRDKNSYELI 255
Query: 177 ADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVP 234
+ F D Q +++QE +P G P+++ ++ V+ V+ GDR G P
Sbjct: 256 HNLCQFTDKQYVKLQEQPENVPEGYTPQTVNLVPYDYNVDDVKPGDRIIVVGVYRAAP 313
>UniRef50_A7QHE6 Cluster: Chromosome chr2 scaffold_97, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr2 scaffold_97, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 239
Score = 53.2 bits (122), Expect = 3e-05
Identities = 30/76 (39%), Positives = 44/76 (57%), Gaps = 1/76 (1%)
Query: 146 VHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRS 205
V+PEL +P+ C + CA F L D + D+Q+I+IQE+ L G IPRS
Sbjct: 161 VYPELETRNAILLPSSCPSQKCAGTN-FQLVEDSIIRHDYQEIKIQESVQVLGVGAIPRS 219
Query: 206 LEVILRAEAVESVQAG 221
+ VIL+ + V+ V+AG
Sbjct: 220 IPVILQDDLVDIVKAG 235
>UniRef50_Q3LW45 Cluster: Chromosome maintenance protein MCM4; n=1;
Bigelowiella natans|Rep: Chromosome maintenance protein
MCM4 - Bigelowiella natans (Pedinomonas minutissima)
(Chlorarachnion sp.(strain CCMP 621))
Length = 610
Score = 50.8 bits (116), Expect = 1e-04
Identities = 61/328 (18%), Positives = 136/328 (41%), Gaps = 14/328 (4%)
Query: 316 WDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVC 375
+ K + ++ LY +I + P+I G +K+ +L M+ +K + ++N
Sbjct: 268 FSKFFSLASTPYLYYIIINHIIPNIGGIINIKKCILCMILSSSSKNRL---IQNSNVNAL 324
Query: 376 IVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLAD 435
D K + K +S + + + + + + + +L
Sbjct: 325 FYSDNLGFKKHIFKILSYYNQEMIEFNS-SYHIHDYKLSTIDKKSTLRQNYSNKFFLLYS 383
Query: 436 NGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRA 495
N ID F+ MD + + E M IS+ + I + N ++++
Sbjct: 384 NAFVLIDRFENMDFNTKALLEEIMTYGKISINYNTKIYFFSCTPRIFSWYNIKANKFNKF 443
Query: 496 KSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESY----DCVYSR 551
L +N+ + + ++FDL F +S + + + I D + ++ + +
Sbjct: 444 -DLVKNMMENFYLNNKFDLLFKNYIHNSRLSN--LFSTITDKYSFSLQTVIFYKQFSFPK 500
Query: 552 DDLLRYIAFARSF-KPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAE 610
L +Y+ F RS+ +P+IT++ L+ YY ++ L S+++++
Sbjct: 501 ILLRKYLLFTRSYVEPIITKDKLNYLIYYYLNLRLLNKKIKNLL--PSIHFLISIIKISI 558
Query: 611 GVAKMHCSGHVTPAHVHEAYRLLNKSII 638
VAK++C+ V+ +H+ EA ++ N S++
Sbjct: 559 CVAKINCNLTVSFSHLKEAIKITNSSLL 586
>UniRef50_Q2GJW8 Cluster: Magnesium chelatase, subunit D/I family,
ComM subfamily; n=7; Rickettsiales|Rep: Magnesium
chelatase, subunit D/I family, ComM subfamily -
Anaplasma phagocytophilum (strain HZ)
Length = 517
Score = 49.6 bits (113), Expect = 3e-04
Identities = 64/305 (20%), Positives = 120/305 (39%), Gaps = 49/305 (16%)
Query: 370 GDINVCIVGDPSTAKSQLLKQVS----EITPRAVYTSGKASSAAG------LTAAVVRDE 419
G+ N+ ++G P T KS + K++ ++TP + SS +T+ R+
Sbjct: 222 GEHNLLMIGPPGTGKSMIAKRIPGILPDLTPEEIIAINVISSITQSGIEYLITSRPFREP 281
Query: 420 ESFDFV---------IEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAG 470
S + G + LA NG+ +DE + A+ + +E +++ +A+A
Sbjct: 282 HSSASMPSIVGGGMRAHPGEITLAHNGILFLDELPEFSKSVLEALRQPLEDKSVVIARAN 341
Query: 471 VRATLNARTSILAAANPI--------GGRYDRAK--SLQQNVALSPPIMSRFDL------ 514
T A ++AA NP R RA +++ +S PI+SR D+
Sbjct: 342 SHITYPANFQLVAAMNPCKCGYLNDPNRRCSRAPKCAIEYQRRISGPILSRIDIKVEMGN 401
Query: 515 --FFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEA 572
F I S E + R+++ +E Y R+ L P + A
Sbjct: 402 VSVFSKITGSKEENSSEMKRRVMSARLFQERRYGDATKRNAFLSAHDVESFVIPYMCSNA 461
Query: 573 GKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRL 632
+LL + + +++ R ++++A +A + CS + HV EA L
Sbjct: 462 RRLLEQVFQRN------------QLSNRDSAKILKVARTIADLSCSEEILEEHVAEAISL 509
Query: 633 LNKSI 637
++
Sbjct: 510 FGHNV 514
>UniRef50_Q01EK8 Cluster: Replication licensing factor MCM7
homologue; n=1; Ostreococcus tauri|Rep: Replication
licensing factor MCM7 homologue - Ostreococcus tauri
Length = 354
Score = 44.8 bits (101), Expect = 0.009
Identities = 19/70 (27%), Positives = 35/70 (50%)
Query: 162 CRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAG 221
C++ C ++ S F +Q++RIQE ++P G +PRS+ V L + + G
Sbjct: 241 CQSQTCNKNFALFIETRASKFAKYQELRIQELSEDVPVGHVPRSMSVTLIGDMTRKLSPG 300
Query: 222 DRYDFTGTLI 231
D + +G +
Sbjct: 301 DIANISGIFL 310
>UniRef50_A5DWW4 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 231
Score = 44.8 bits (101), Expect = 0.009
Identities = 28/142 (19%), Positives = 64/142 (45%), Gaps = 6/142 (4%)
Query: 25 FQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFL 84
FQ+FL+ + I Y + L+ + L VS D + +++ ++ + P
Sbjct: 23 FQEFLDRDDANTGINYRSQIRNLIIKSKNRLNVSIDQIRDFDREFWQGLLNQPADYLPAC 82
Query: 85 NRAILNYILSL---AETGMKKDL-QDKECYVSFVDVPTRHKV--RELTTAKIGTLIRISG 138
RA+ + +L++ +++ + ++ Y+SF H V R + ++ + ++ I G
Sbjct: 83 ERALRDTVLTIYDPSDSDFPSEFDSSQQYYLSFKGAFGSHSVTARSIDSSYLSKMVSIEG 142
Query: 139 QIVRTHPVHPELVQGTFYTIPT 160
+ R V P++++ Y T
Sbjct: 143 IVTRASLVRPKVIRSVHYAEAT 164
>UniRef50_Q4SGA7 Cluster: Chromosome 17 SCAF14597, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 17 SCAF14597, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 546
Score = 44.0 bits (99), Expect = 0.016
Identities = 34/96 (35%), Positives = 48/96 (50%), Gaps = 4/96 (4%)
Query: 143 THPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR-- 199
+H + L QG F T PT C P C +R + + VD+Q I++QE A+ R
Sbjct: 159 SHTMSLLLQQGKFET-PTKCGLPGCRSRSFVPCQSSPLTQTVDWQIIKVQELIADEQRET 217
Query: 200 GCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPD 235
G IPR++E L A+ +S GD TG + V D
Sbjct: 218 GRIPRTMECHLTADLCDSCVPGDTVTVTGIVRVAND 253
>UniRef50_Q2FLV5 Cluster: Magnesium chelatase, ChlI subunit; n=1;
Methanospirillum hungatei JF-1|Rep: Magnesium chelatase,
ChlI subunit - Methanospirillum hungatei (strain JF-1 /
DSM 864)
Length = 619
Score = 44.0 bits (99), Expect = 0.016
Identities = 41/156 (26%), Positives = 66/156 (42%), Gaps = 22/156 (14%)
Query: 337 FPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITP 396
F I G NE K +LL L V ++ I ++G T KS L + +T
Sbjct: 8 FADIKGLNEAKLSLLLFLVSPVIRSLI------------LIGGTGTGKSHLARLTKSVTD 55
Query: 397 -RAVY-----TSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPG 450
+ V+ T + + +TA++ R E+ VIE G L AD G+ +D+ MD
Sbjct: 56 VKTVHLPQHATWDRVFGSIDITASLARGEK----VIEHGLLKKADGGIVIMDDIHLMDHT 111
Query: 451 DQVAIHEAMEQQTISLAKAGVRATLNARTSILAAAN 486
A+ A E + + + G+ + I+A N
Sbjct: 112 LITAVLSAAETGMVKIERDGISSGYQTNFKIIATLN 147
>UniRef50_A4M6H9 Cluster: Mg chelatase, subunit ChlI precursor; n=1;
Petrotoga mobilis SJ95|Rep: Mg chelatase, subunit ChlI
precursor - Petrotoga mobilis SJ95
Length = 499
Score = 43.6 bits (98), Expect = 0.021
Identities = 69/304 (22%), Positives = 118/304 (38%), Gaps = 30/304 (9%)
Query: 359 AKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITP----RAVYTSGKASSAAGLTAA 414
AK IE G NV + G P + K+ + K+V I P + S S AG
Sbjct: 202 AKRGIE-IAASGFHNVLMRGSPGSGKTMIAKRVPTILPDMTREEIIESTMIYSVAGYMNT 260
Query: 415 VVRDEESF---------------DFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAM 459
++ D+ F V + G + LA NGV +DEF + ++ + +
Sbjct: 261 II-DKRPFRSPHHTASTASIIGGGAVPKPGEISLAHNGVLFMDEFPEYRTDVIESLRQPL 319
Query: 460 EQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILI 519
E +++ +A A AR ++A+ NP Y K ++ +L+ + + ++
Sbjct: 320 EDGEVTVTRAKSVANFPARFMLIASQNPCPCGYYGDKEIECTCSLNQILNYNRKISGPIL 379
Query: 520 DESSEMVDYAIARKIVDLHCNKE--ESYDCVYSRDDLLRYIAFARSFK---PVITEEAGK 574
D +D R +D +KE ES + + R I R K + +E K
Sbjct: 380 DRIDIRID--TPRVKIDELMSKEDGESSEKIKERVSKASQIQIKRQNKLNGKLSNKELKK 437
Query: 575 LLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN 634
V ++T R + +VR++ +A S +V +HV EA
Sbjct: 438 FAV--LSEKAEDFLKQAAINLKLTARSVNRVVRISRTIADTFDSKNVEISHVSEALNYRG 495
Query: 635 KSII 638
+ II
Sbjct: 496 RKII 499
>UniRef50_A5DYY2 Cluster: Putative uncharacterized protein; n=1;
Lodderomyces elongisporus NRRL YB-4239|Rep: Putative
uncharacterized protein - Lodderomyces elongisporus
(Yeast) (Saccharomyces elongisporus)
Length = 216
Score = 43.2 bits (97), Expect = 0.028
Identities = 33/119 (27%), Positives = 57/119 (47%), Gaps = 9/119 (7%)
Query: 535 VDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXX 594
+ L EE + + S+ + YI+ AR+++PV+ +E G +V+ Y
Sbjct: 10 IQLANGAEEEFQPIDSKT-IREYISKARTYRPVVPQEVGDYVVQSYINMRKESQRNEGSI 68
Query: 595 WR---ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDED 650
+ IT R L ++RLA+ A++ + VT V EA RL I V + ++ DE+
Sbjct: 69 KKFSHITPRTLLGILRLAQASARLRFTDLVTMEDVDEALRL-----IEVSKSSLYADEE 122
>UniRef50_UPI000050C0BA Cluster: MCM complex subunit; AAA ATPase;
n=1; Schizosaccharomyces pombe 972h-|Rep: MCM complex
subunit; AAA ATPase - Schizosaccharomyces pombe 972h-
Length = 276
Score = 42.7 bits (96), Expect = 0.037
Identities = 24/63 (38%), Positives = 36/63 (57%), Gaps = 1/63 (1%)
Query: 597 ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRL-LNKSIIRVEQPDIHLDEDEPQCE 655
ITVRQLE+++R+ E +AKM S + AH EA RL L ++ Q + E+ + E
Sbjct: 157 ITVRQLEAIIRITESLAKMSLSPIASEAHATEAIRLFLTSTLAAATQSSPEVTEEVKKIE 216
Query: 656 PSM 658
S+
Sbjct: 217 ASL 219
Score = 35.1 bits (77), Expect = 7.5
Identities = 18/67 (26%), Positives = 32/67 (47%)
Query: 22 QKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIY 81
+K F F+EEF DN+ Y ++ L + L + + YN++LA ++ + I
Sbjct: 31 EKNFIQFIEEFVIDNDFIYRTQLRDNLVVKQYMLNIDLRHLISYNEDLAHLLLSQPTDIL 90
Query: 82 PFLNRAI 88
P A+
Sbjct: 91 PLFESAV 97
>UniRef50_Q897H3 Cluster: Regulatory protein moxR; n=1; Clostridium
tetani|Rep: Regulatory protein moxR - Clostridium tetani
Length = 324
Score = 42.7 bits (96), Expect = 0.037
Identities = 49/225 (21%), Positives = 93/225 (41%), Gaps = 17/225 (7%)
Query: 345 EVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITP----RAVY 400
E+K+G++ V K + G G NV + G P K+QL+K + ++ R +
Sbjct: 19 EIKKGIIGQ--DEVIKNLLIGVIAGG--NVLLEGMPGLGKTQLVKTIGKVLDLEFSRIQF 74
Query: 401 TSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAME 460
T S + + + E+ +F + G + + + DE ++ P Q A+ EAME
Sbjct: 75 TPDLMPSDIVGSEIIRKKNENIEFTFKKGPIF---SSIILADEINRATPKTQSALLEAME 131
Query: 461 QQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILID 520
++ +++ L +LA NP+ + + A M + ++ F I+
Sbjct: 132 EKRVTVGNKTYE--LPNPFFVLATQNPL----ETEGTYPLPEAQLDRFMFKVNIDFPDIE 185
Query: 521 ESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSFK 565
S +VD + +D NK + V ++ R + A K
Sbjct: 186 AISTIVDLTTSNYSIDEKINKVLDREKVLKMREISRTVLIAEPIK 230
>UniRef50_A7MLA0 Cluster: Putative uncharacterized protein; n=1;
Enterobacter sakazakii ATCC BAA-894|Rep: Putative
uncharacterized protein - Enterobacter sakazakii ATCC
BAA-894
Length = 546
Score = 42.7 bits (96), Expect = 0.037
Identities = 30/94 (31%), Positives = 47/94 (50%), Gaps = 8/94 (8%)
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP- 487
G + LA NGV +DE + + A+ E +E I L++ + T AR ++AA NP
Sbjct: 328 GEISLAHNGVLFLDELPEFERRVLDALREPIESGQIHLSRTRAKLTYPARFQLIAAMNPS 387
Query: 488 ----IGGRYDRA---KSLQQNVALSPPIMSRFDL 514
G ++R ++L+ LS P + RFDL
Sbjct: 388 PTGHYKGNHNRCSPEQTLRYLGRLSGPFLDRFDL 421
>UniRef50_A6C1F0 Cluster: Probable two-component response regulator;
n=1; Planctomyces maris DSM 8797|Rep: Probable
two-component response regulator - Planctomyces maris
DSM 8797
Length = 673
Score = 42.7 bits (96), Expect = 0.037
Identities = 40/136 (29%), Positives = 62/136 (45%), Gaps = 14/136 (10%)
Query: 360 KTTIEGTTLRG-DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRD 418
++TIE L G D+ V I+G+ T K + + + PRA T A + A LT ++
Sbjct: 366 RSTIE--RLAGTDLPVLILGESGTGKEVVSQSLHYQGPRA-NTPFIAVNCAALTETLLES 422
Query: 419 E----ESFDFV----IEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAG 470
E E F AG LA+ G +DE M PG Q + +EQ+ ++ + G
Sbjct: 423 ELFGHEKGAFTDAHETRAGKFELAEGGTLFLDEIGDMSPGGQAKLLRVLEQKVVT--RVG 480
Query: 471 VRATLNARTSILAAAN 486
T+ ++AA N
Sbjct: 481 GSETIPINVRVVAATN 496
>UniRef50_Q81EV1 Cluster: MCM domain family protein; n=1; Bacillus
cereus ATCC 14579|Rep: MCM domain family protein -
Bacillus cereus (strain ATCC 14579 / DSM 31)
Length = 1028
Score = 42.3 bits (95), Expect = 0.049
Identities = 51/202 (25%), Positives = 88/202 (43%), Gaps = 14/202 (6%)
Query: 368 LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIE 427
LRG + + IVGD T KS L+++V + + + +++S GLT + + + I
Sbjct: 637 LRGWVELKIVGDTGTGKSALIEKVMKYSGLGTRVNAESTSRTGLTYKMEQSGAQGAWYIV 696
Query: 428 AGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP 487
GA LAD + IDE + D + A + + +A T +I++ P
Sbjct: 697 WGAWPLADKEMIWIDEDTGITKDDYGEMTLARSDGKLEVKRAVTAETPCRVRAIMSGNVP 756
Query: 488 IGGR---YDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544
G R Y + +++ + I RFD F + +S+ VD +L+ +
Sbjct: 757 KGKRLADYSQGAESLKDIFNNEDI-RRFD--FAVFMRASD-VD-------PELYNQTLAT 805
Query: 545 YDCVYSRDDLLRYIAFARSFKP 566
Y + +D L I +A S KP
Sbjct: 806 YPSIIQKDTLKNNILYAWSRKP 827
>UniRef50_A6EHC4 Cluster: Sigma-54-dependent transcriptional
regulator; n=1; Pedobacter sp. BAL39|Rep:
Sigma-54-dependent transcriptional regulator -
Pedobacter sp. BAL39
Length = 550
Score = 42.3 bits (95), Expect = 0.049
Identities = 35/124 (28%), Positives = 56/124 (45%), Gaps = 11/124 (8%)
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE------ESFDF 424
D V I+G+ T K + + + ++PR K + AA L A +V E SF
Sbjct: 259 DSTVLILGETGTGKELVARSIHNLSPRKDKLMIKVNCAA-LPANLVESELFGHEKGSFTG 317
Query: 425 VIEA--GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSIL 482
E G LA NG +DE ++ P QV + A++++ I + G + + I+
Sbjct: 318 ASERRIGKFELAHNGTLFLDEIGELSPDIQVKLLRALQEKEIE--RIGGKGVIKTNVRII 375
Query: 483 AAAN 486
AA N
Sbjct: 376 AATN 379
>UniRef50_UPI0000E10DEA Cluster: competence protein ComM; n=1; alpha
proteobacterium HTCC2255|Rep: competence protein ComM -
alpha proteobacterium HTCC2255
Length = 518
Score = 41.5 bits (93), Expect = 0.086
Identities = 43/170 (25%), Positives = 73/170 (42%), Gaps = 25/170 (14%)
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSA----AGLTAAVVRDEESF--- 422
G N+ + G P + K+ L ++++ I P T ++A AGL A + F
Sbjct: 216 GGHNLLLYGAPGSGKTMLAERIASIMPPLTQTQAIENAAIHSVAGLDVASLWGRRPFRQP 275
Query: 423 --DFVIEA----------GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAG 470
I A G + LA++GV +DE + + + +E TI++A+A
Sbjct: 276 HHSSSIPALTGGGVKFCPGEMTLANHGVLFLDELAEFSAHALDHLRQPLEANTIAVARAQ 335
Query: 471 VRATLNARTSILAAAN--PIGGRYDRAKSLQQNV----ALSPPIMSRFDL 514
L A ++AA N P G Y+ + Q V +S P++ R D+
Sbjct: 336 YHLILPAHFQLIAAMNPSPTGDIYNNRSTYDQTVRYLQRVSGPLLDRIDI 385
>UniRef50_Q2RH79 Cluster: Sigma54 specific transcriptional regulator
with PAS sensor, Fis family; n=1; Moorella thermoacetica
ATCC 39073|Rep: Sigma54 specific transcriptional
regulator with PAS sensor, Fis family - Moorella
thermoacetica (strain ATCC 39073)
Length = 562
Score = 41.1 bits (92), Expect = 0.11
Identities = 40/156 (25%), Positives = 64/156 (41%), Gaps = 10/156 (6%)
Query: 339 SIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRA 398
SI G+ + +G+L + V + RG+ NV I G+ T K L + + +PR
Sbjct: 244 SIQGDQDAWQGILGVSPAMVRLKKMAARVARGEANVLITGESGTGKELLAQAIHRASPRR 303
Query: 399 VYTSGKASSAA---GLTAAVVRDEESFDFVIEA-----GALMLADNGVCCIDEFDKMDPG 450
K + AA L A + E F A G LAD G +DE +
Sbjct: 304 NEPLIKINCAAIPENLLEAELFGYEEGAFTGAARGGKPGKFELADGGTIFLDEVGDLPLS 363
Query: 451 DQVAIHEAMEQQTISLAKAGVRATLNARTSILAAAN 486
Q + ++++ + + G R T+ I+AA N
Sbjct: 364 MQPKLLRVLQER--AFERVGGRRTIKVDVRIIAATN 397
>UniRef50_Q2JEZ9 Cluster: AAA_3 ATPase associated with various
cellular activities; n=15; Actinomycetales|Rep: AAA_3
ATPase associated with various cellular activities -
Frankia sp. (strain CcI3)
Length = 351
Score = 41.1 bits (92), Expect = 0.11
Identities = 42/156 (26%), Positives = 70/156 (44%), Gaps = 19/156 (12%)
Query: 345 EVKRGVLLMLFGGVAKTTI-EGTTLRGDI-------NVCIVGDPSTAKSQLLKQVSEI-- 394
+ R L+ L G VAK I + + G + + + G P AK+ L++ ++
Sbjct: 37 QTARRSLIALRGEVAKAVIGQDAAVSGLVIALLCRGHALLEGVPGVAKTLLVRTLATALA 96
Query: 395 --TPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQ 452
T R +T +T ++V D S +F G + + DE ++ P Q
Sbjct: 97 LDTKRLQFTPDLMPG--DVTGSLVYDNRSSEFTFREGPVF---TNLLLADEINRTPPKTQ 151
Query: 453 VAIHEAMEQQTISLAKAGVRATLNARTSILAAANPI 488
A+ E ME++ +S+ AGV L A ++LA NPI
Sbjct: 152 AALLEVMEERQVSV--AGVPRPLPAPFAVLATQNPI 185
>UniRef50_A6LSN6 Cluster: Mg chelatase, subunit ChlI; n=1;
Clostridium beijerinckii NCIMB 8052|Rep: Mg chelatase,
subunit ChlI - Clostridium beijerinckii NCIMB 8052
Length = 506
Score = 40.3 bits (90), Expect = 0.20
Identities = 45/206 (21%), Positives = 84/206 (40%), Gaps = 21/206 (10%)
Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITP----RAVYTSGKASSAAGLTAAVVRDEESFDFV 425
G N+ + G+P K+ L K + I P + K SA GL + R F
Sbjct: 211 GKHNIILYGEPGCGKTMLAKALISILPSLSQEELIEIAKIYSACGLMTRISRLNRPFRAP 270
Query: 426 ---------------IEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAG 470
I G + LA NGV +DE + ++ E +E++ +++ +
Sbjct: 271 HHTTTRIALIGGGKEIRPGEITLAHNGVLFLDEILEFKKDVLESLREPLEEKNVNINRLS 330
Query: 471 VRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAI 530
+ A ++ A NP+ D+ + L+ I F + + ++++Y +
Sbjct: 331 GSYQMPADFLLIGAFNPVENNEDKDFN-DSKYYLNTKITKYSRKFSSALLDRIDILNY-V 388
Query: 531 ARKIVDLHCNKEESYDCVYSRDDLLR 556
R D NK++SYD ++++LR
Sbjct: 389 PRLNYDEIENKKDSYDSKAMKENVLR 414
>UniRef50_Q4SVP9 Cluster: Chromosome undetermined SCAF13748, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF13748,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 349
Score = 39.9 bits (89), Expect = 0.26
Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 9/94 (9%)
Query: 140 IVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDA-----DKSVFVDFQKIRIQETQ 194
I+ P+ P L QG Y +P C N A R + +D D+ V +DFQ +R+QE+
Sbjct: 132 IINNIPLPPGL-QG--YALPRKC-NVENAGRMKCPVDPYFIIPDRCVCIDFQTLRLQESP 187
Query: 195 AELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228
+P G +PR L++ + V G+R G
Sbjct: 188 DAVPHGEMPRHLQLYCDRYLCDRVVPGNRVTIMG 221
Score = 37.5 bits (83), Expect = 1.4
Identities = 20/42 (47%), Positives = 25/42 (59%)
Query: 597 ITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSII 638
ITVRQLE++VR+AE +AKM V EA RL S +
Sbjct: 294 ITVRQLEAVVRIAESLAKMKLQAVAGEEEVDEALRLFQVSTL 335
>UniRef50_A6DKK7 Cluster: ATPase, AAA family protein; n=1;
Lentisphaera araneosa HTCC2155|Rep: ATPase, AAA family
protein - Lentisphaera araneosa HTCC2155
Length = 337
Score = 39.9 bits (89), Expect = 0.26
Identities = 55/240 (22%), Positives = 104/240 (43%), Gaps = 25/240 (10%)
Query: 344 NEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEIT----PRAV 399
N++K + +LFG + T L ++ + G P K++L+K +S+ R
Sbjct: 18 NKLKTCLNQVLFGQEELVDLVCTGLFARGHLLLEGLPGLGKTELIKGLSKALGLDFKRIQ 77
Query: 400 YTSGKA-SSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEA 458
+T +G RD E +FV +AG + + DE ++ P Q A+ EA
Sbjct: 78 FTPDLLPGDISGNPLIQERDGEK-EFVFQAGPIF---GNLILADEINRASPKTQSAMLEA 133
Query: 459 MEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFIL 518
M+++++++ AG L +LA NPI L+ AL ++ D F
Sbjct: 134 MQEKSVTV--AGQSHELPDPFFVLATQNPI--------ELEGTYALPE---AQLDRFLFK 180
Query: 519 IDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVE 578
+D D + R ++ + + V SRD+L + I+ + K I ++ +++ +
Sbjct: 181 LDVHHAPAD-VLERIVLSRELGESPKVEQVLSRDELQKMISLVK--KVHIPQQVAQMIAQ 237
>UniRef50_A1SGQ7 Cluster: ATPase associated with various cellular
activities, AAA_3 precursor; n=3; Actinomycetales|Rep:
ATPase associated with various cellular activities,
AAA_3 precursor - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 340
Score = 39.9 bits (89), Expect = 0.26
Identities = 25/80 (31%), Positives = 41/80 (51%), Gaps = 5/80 (6%)
Query: 409 AGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAK 468
A LT + + D+ +F G L G+ DE ++ P Q A+ EAM+++ +++
Sbjct: 98 ADLTGSFIYDQRRGEFEFRRGPLF---TGLLLADEINRTPPKTQAALLEAMQERQVTV-- 152
Query: 469 AGVRATLNARTSILAAANPI 488
G L+A +LA ANPI
Sbjct: 153 EGETFPLSAPFHVLATANPI 172
>UniRef50_A2DZ79 Cluster: Putative uncharacterized protein; n=2;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 717
Score = 39.9 bits (89), Expect = 0.26
Identities = 44/178 (24%), Positives = 77/178 (43%), Gaps = 12/178 (6%)
Query: 234 PDVGALSMPGSRAE-ITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRF 292
P+ S S AE I + + A E + + K +E+ +A S ++V +
Sbjct: 115 PERVQTSFEASVAENIAKKQQEAAEKEKQAAKSPDIKKEKEMASFNRLIAISNKSVQEAY 174
Query: 293 GTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLY---NNLITSLFPSIHGNNEVKRG 349
+ L T D + ++T ++D++ +S++ Y N+L+T+ +G +E++
Sbjct: 175 LESTLAAFASTEPDQKAKLT--KFDQLSNLSKNTAYYDFINHLVTNQMAPNYGTSELQDE 232
Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASS 407
V + + TI DIN I G PST KS L +S I R + S S
Sbjct: 233 VDAWCMDALNQLTIS------DINFIISGLPSTGKSSTLYSLSTILFRKIQQSSANGS 284
>UniRef50_A0RXY9 Cluster: Mg-chelatase subunit; n=1; Cenarchaeum
symbiosum|Rep: Mg-chelatase subunit - Cenarchaeum
symbiosum
Length = 585
Score = 39.9 bits (89), Expect = 0.26
Identities = 21/60 (35%), Positives = 31/60 (51%), Gaps = 2/60 (3%)
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPI 488
G LM A +G+ CIDE +DP QVA+ +++ + V RT + A ANP+
Sbjct: 263 GQLMQAKHGIFCIDELPVLDPRKQVALLSVLQEGRFTTGPYPV--YFEPRTMLFATANPV 320
>UniRef50_Q9WYY3 Cluster: ComM protein; n=3; Thermotogaceae|Rep:
ComM protein - Thermotoga maritima
Length = 501
Score = 39.5 bits (88), Expect = 0.35
Identities = 36/147 (24%), Positives = 64/147 (43%), Gaps = 18/147 (12%)
Query: 358 VAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITP----RAVYTSGKASSAAGLTA 413
+ K +E + G N+ +VG+P + K+ + K++ I P + + K SA+G
Sbjct: 201 MVKRAVE-IAVAGFHNILMVGNPGSGKTMIAKRIPTIFPPMSEEEILETSKVYSASGYPG 259
Query: 414 AVV-------RDEESFDFVIEAGA------LMLADNGVCCIDEFDKMDPGDQVAIHEAME 460
V S +I G + LA NGV +DE + A+ + +E
Sbjct: 260 IVKLRPFRAPHHTASTVSIIGGGTNPRPGEISLAHNGVLFLDELPEFKRDVLEALRQPLE 319
Query: 461 QQTISLAKAGVRATLNARTSILAAANP 487
+ +++A+A T AR ++ A NP
Sbjct: 320 EGIVTVARAKFTVTYPARFMLVGAMNP 346
>UniRef50_Q5QZ88 Cluster: Competence related ATPase with chaperone
activity; n=16; Gammaproteobacteria|Rep: Competence
related ATPase with chaperone activity - Idiomarina
loihiensis
Length = 515
Score = 39.5 bits (88), Expect = 0.35
Identities = 47/229 (20%), Positives = 92/229 (40%), Gaps = 18/229 (7%)
Query: 426 IEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAA 485
+ G + LA+NG+ +DE + + E + I++++AG A ++ A
Sbjct: 290 VRPGEISLANNGLLFLDEMPEFSRHVLDCLREPLGSGEITISRAGYNVKFPANFQLVCAL 349
Query: 486 NPIG-GRYD----RAKSLQQNV-----ALSPPIMSRFDLFFILIDESSEM-VDYAIARKI 534
NP G++D +S + LS P++ R D+ ++ ES M + A K
Sbjct: 350 NPSPCGQFDGSLANCRSTPDQILKYLSKLSGPLLDRIDIQVMVPRESESMSLKGATKHKT 409
Query: 535 VDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXX 594
+ + +S L+R KP + ++ + +
Sbjct: 410 QPMTSLQAKSLVEKARHRQLMRQGCLNSELKPKVLKQ-----ICFLSEQSEAFLAKAAEK 464
Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEA--YRLLNKSIIRVE 641
+++ R +RLA +A + S + H+ EA YR L++ I +V+
Sbjct: 465 MKLSHRAYHRTLRLARTIADLADSKKIEQQHLAEALNYRALDRLIEQVQ 513
>UniRef50_Q0LJV9 Cluster: ATPase associated with various cellular
activities, AAA_3 precursor; n=2; Bacteria|Rep: ATPase
associated with various cellular activities, AAA_3
precursor - Herpetosiphon aurantiacus ATCC 23779
Length = 329
Score = 39.5 bits (88), Expect = 0.35
Identities = 33/127 (25%), Positives = 58/127 (45%), Gaps = 10/127 (7%)
Query: 367 TLRGDINVCIVGDPSTAKSQLLKQVSEITP----RAVYTSGKASSAAGLTAAVVRDEESF 422
TL N + G P AK+ L++ +SE R +T + T + DE+
Sbjct: 39 TLIAGGNALLEGVPGLAKTTLIRTLSEAVDCQFSRIQFTPDLMPADIIGTTIIAEDEQGQ 98
Query: 423 -DFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSI 481
+F + G + + + DE ++ P Q A+ EAM++ T+S+A+ + L +
Sbjct: 99 KEFRFQRGPIF---SNLVLADEINRATPKTQSALLEAMQEHTVSVARTSYK--LEEPFFV 153
Query: 482 LAAANPI 488
LA NP+
Sbjct: 154 LATQNPL 160
>UniRef50_Q4UM51 Cluster: Mg chelatase-related protein; n=18;
Alphaproteobacteria|Rep: Mg chelatase-related protein -
Rickettsia felis (Rickettsia azadi)
Length = 416
Score = 39.1 bits (87), Expect = 0.46
Identities = 49/219 (22%), Positives = 90/219 (41%), Gaps = 23/219 (10%)
Query: 426 IEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAA 485
++ G + LA NGV +DE + ++ + +E I ++++ A ++AA
Sbjct: 195 VKPGEITLAHNGVLFLDELPEFPHNVIDSLRQPIENGEILISRSSAHIKYPANFQLIAAM 254
Query: 486 NP-----IGGRYDRAKSLQQ-----NVALSPPIMSRFDLFFILIDESSEMVDYAIARKIV 535
NP +G Y + + +S PIM RFDL + + + D+ I
Sbjct: 255 NPCKCGYLGDTYKECMKAPKCDSDYQMKVSGPIMDRFDLHIEVSNINIYNYDF-----IT 309
Query: 536 DLHCNKEESYDCVYSRDDLLRYIAFAR-SFKPVITEEA--GKLLVEYY--XXXXXXXXXX 590
D N EE + + R + +R I R + T G+LL++Y
Sbjct: 310 D---NSEEKSEDIAIRVENVRLIQEKRYEGYNIKTNNRLDGQLLIDYAMPADEGRDLLNE 366
Query: 591 XXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEA 629
+R+++R ++R+A +A + V H+ EA
Sbjct: 367 AANKFRLSMRVYNRILRVARTIADLENVDKVLKIHIAEA 405
>UniRef50_A7BDE3 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 504
Score = 39.1 bits (87), Expect = 0.46
Identities = 27/95 (28%), Positives = 45/95 (47%), Gaps = 9/95 (9%)
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP- 487
GA LA G+ +DE + P ++ E +E I + ++GV+A A ++ A+NP
Sbjct: 290 GAASLAHGGILFLDEAAEFAPSVLDSLREPLESGVIHVHRSGVQARYPAAFQLVMASNPC 349
Query: 488 -----IGGRYDRAKSLQQN---VALSPPIMSRFDL 514
GGR S+ + LS P++ R D+
Sbjct: 350 PCGGGYGGRRCTCSSMNRRRYLARLSGPLLDRMDI 384
>UniRef50_A1VXR8 Cluster: Mg chelatase-related protein; n=10;
Campylobacter|Rep: Mg chelatase-related protein -
Campylobacter jejuni subsp. jejuni serotype O:23/36
(strain 81-176)
Length = 501
Score = 39.1 bits (87), Expect = 0.46
Identities = 32/115 (27%), Positives = 54/115 (46%), Gaps = 11/115 (9%)
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPI 488
G + LA+ GV DEF + ++ E +E I +++ + T + S +AA NP
Sbjct: 296 GEVALANGGVLFFDEFPHFNKQIIESLREPLEDHKIHISRVNSKITYETKFSFIAAQNPC 355
Query: 489 --GGRYDRAKSL--QQNVA------LSPPIMSRFDLFFILIDESSEMVDYAIARK 533
G + + S +N +S PIM R DL ++ +DE S+ +I+ K
Sbjct: 356 PCGNLFSKNLSCVCSENEIKKYKNHISAPIMDRIDL-YVAMDEISKDDKTSISSK 409
>UniRef50_Q9U2P7 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 1435
Score = 39.1 bits (87), Expect = 0.46
Identities = 31/101 (30%), Positives = 56/101 (55%), Gaps = 5/101 (4%)
Query: 12 QVKDEVGIRCQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71
+ K+EV + ++ FQ EEF+++ E K +K KEL K + S +V DDV + +N+
Sbjct: 732 KTKEEVE-KAKEEFQKVKEEFQKEVE-KVKKVEKELEKAKESDFKVYLDDVRRSLKNVRE 789
Query: 72 TIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVS 112
TI E FL+ L ++ S + + +L+D++C ++
Sbjct: 790 TIEETRKYEIRFLDS--LGFMPSSLDC-LSNNLEDEDCKIT 827
>UniRef50_Q1DCC3 Cluster: Mg-chelatase subunits D/I family, ComM
subfamily protein; n=8; Bacteria|Rep: Mg-chelatase
subunits D/I family, ComM subfamily protein - Myxococcus
xanthus (strain DK 1622)
Length = 547
Score = 38.7 bits (86), Expect = 0.61
Identities = 21/59 (35%), Positives = 29/59 (49%)
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP 487
G L LA NGV +DE + + + ME+ I LA+A T R ++AA NP
Sbjct: 293 GELSLAHNGVLFLDELPEFRRNVLEVLRQPMEEGVIHLARANQNITYPCRVMLVAAMNP 351
>UniRef50_P59402 Cluster: Anaerobic nitric oxide reductase
transcription regulator norR; n=81; Proteobacteria|Rep:
Anaerobic nitric oxide reductase transcription regulator
norR - Shigella flexneri
Length = 504
Score = 38.7 bits (86), Expect = 0.61
Identities = 35/124 (28%), Positives = 54/124 (43%), Gaps = 11/124 (8%)
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDE------ESFDF 424
D+NV I G+ T K + K + E +PRAV + AA L +V E +F
Sbjct: 208 DLNVLISGETGTGKELVAKAIHEASPRAVNPLVYLNCAA-LPESVAESELFGHVKGAFTG 266
Query: 425 VI--EAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSIL 482
I +G +ADNG +DE ++ Q + ++ I + G +L +L
Sbjct: 267 AISNRSGKFEMADNGTLFLDEIGELSLALQAKLLRVLQYGDIQ--RVGDDRSLRVDVRVL 324
Query: 483 AAAN 486
AA N
Sbjct: 325 AATN 328
>UniRef50_P45049 Cluster: Competence protein comM; n=220;
Bacteria|Rep: Competence protein comM - Haemophilus
influenzae
Length = 509
Score = 38.7 bits (86), Expect = 0.61
Identities = 30/94 (31%), Positives = 45/94 (47%), Gaps = 8/94 (8%)
Query: 429 GALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPI 488
G + LA NGV +DE + + A+ + +E I +++A + AR ++AA NP
Sbjct: 293 GEISLATNGVLFLDELPEFERKVLDALRQPLESGEIIISRANAKIQFPARFQLVAAMNPS 352
Query: 489 -GGRY---DRAKSLQQNV----ALSPPIMSRFDL 514
G Y S QQ + LS P + RFDL
Sbjct: 353 PTGHYTGTHNRTSPQQIMRYLNRLSGPFLDRFDL 386
>UniRef50_Q1FF57 Cluster: Mg chelatase-related protein; n=5;
Clostridiales|Rep: Mg chelatase-related protein -
Clostridium phytofermentans ISDg
Length = 512
Score = 38.3 bits (85), Expect = 0.80
Identities = 47/186 (25%), Positives = 80/186 (43%), Gaps = 31/186 (16%)
Query: 359 AKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSG----KASSAAGL--- 411
AK IE ++ G N+ ++G P + K+ L K++ I P + K S +G
Sbjct: 204 AKRAIE-VSVAGQHNIMMIGTPGSGKTMLAKRIPSIMPELSFEESLDISKIYSVSGQLDN 262
Query: 412 --TAAVVRDEESFDFVIEAGALM------------LADNGVCCIDEFDKMDPGDQVAIHE 457
+ R S I AL+ LA +GV +DE + D + +
Sbjct: 263 NRVLILERPFRSPHHTITQTALIGGGRCPRPGEISLAAHGVLFLDELTEFDNRTLEVLRQ 322
Query: 458 AMEQQTISLAKAGVRATLNARTSILAAANPIGGRY--DRAK---SLQQNV----ALSPPI 508
+E++ +++++ T A ++AA NP Y DR+K SLQQ +S P+
Sbjct: 323 PLEEKVVTISRLHATYTYPANFMLVAALNPCKCGYYPDRSKCKCSLQQIKQYIGKISRPL 382
Query: 509 MSRFDL 514
+ R D+
Sbjct: 383 LDRIDI 388
>UniRef50_Q5V2T6 Cluster: Methanol dehydrogenase regulatory protein;
n=4; cellular organisms|Rep: Methanol dehydrogenase
regulatory protein - Haloarcula marismortui
(Halobacterium marismortui)
Length = 313
Score = 37.9 bits (84), Expect = 1.1
Identities = 33/122 (27%), Positives = 53/122 (43%), Gaps = 9/122 (7%)
Query: 371 DINVCIVGDPSTAKSQLLKQVSEITP----RAVYTSGKASSAAGLTAAVVRDEESFDFVI 426
D N + +P K+ +++ V+E+T R T S T + + +FV
Sbjct: 42 DGNALLESNPGLGKTTMVRTVAEVTDLQFSRIQNTPDLMPSDITGTEIIRETDSGREFVF 101
Query: 427 EAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAAN 486
E G + V DE ++ P Q A+ EAM+++ ++ AG L ILA N
Sbjct: 102 EKGPVFA---NVVLADEINRATPKTQAALLEAMQEKQVT--AAGETYELPRPFFILATQN 156
Query: 487 PI 488
PI
Sbjct: 157 PI 158
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.380
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 801,433,826
Number of Sequences: 1657284
Number of extensions: 31802407
Number of successful extensions: 97519
Number of sequences better than 10.0: 290
Number of HSP's better than 10.0 without gapping: 231
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 96417
Number of HSP's gapped (non-prelim): 743
length of query: 799
length of database: 575,637,011
effective HSP length: 107
effective length of query: 692
effective length of database: 398,307,623
effective search space: 275628875116
effective search space used: 275628875116
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
S2: 76 (34.7 bits)
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