BLASTP 2.2.12 [Aug-07-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= BGIBMGA000828-TA|BGIBMGA000828-PA|IPR008994|Nucleic acid-binding, OB-fold, IPR001208|MCM, IPR008049|MCM protein 6 (799 letters) Database: human 224,733 sequences; 73,234,838 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value D84557-1|BAA12699.1| 821|Homo sapiens HsMcm6 protein. 975 0.0 BC032374-1|AAH32374.1| 821|Homo sapiens minichromosome maintena... 975 0.0 AY220757-1|AAO26043.1| 821|Homo sapiens MCM6 minichromosome mai... 975 0.0 U46838-1|AAC50766.1| 821|Homo sapiens p105MCM protein. 954 0.0 AC011893-4|AAX88925.1| 785|Homo sapiens unknown protein. 947 0.0 X74794-1|CAA52801.1| 923|Homo sapiens P1 Cdc21 protein protein. 278 5e-74 BC031061-1|AAH31061.1| 863|Homo sapiens minichromosome maintena... 278 6e-74 AY588245-1|AAS83108.1| 863|Homo sapiens MCM4 minichromosome mai... 278 6e-74 D83986-1|BAA12176.1| 733|Homo sapiens huMCM5 protein. 277 1e-73 X74795-1|CAA52802.2| 734|Homo sapiens P1 Cdc46 protein. 275 3e-73 CR456517-1|CAG30403.1| 734|Homo sapiens MCM5 protein. 275 3e-73 BC000142-1|AAH00142.1| 734|Homo sapiens minichromosome maintena... 275 3e-73 AY212028-1|AAO21127.1| 734|Homo sapiens MCM5 minichromosome mai... 275 3e-73 BC003656-1|AAH03656.1| 734|Homo sapiens minichromosome maintena... 275 5e-73 AK223323-1|BAD97043.1| 734|Homo sapiens minichromosome maintena... 275 5e-73 Z82244-2|CAB05110.1| 733|Homo sapiens MCM5 minichromosome maint... 271 6e-72 D38073-1|BAA07267.1| 808|Homo sapiens hRlf beta subunit (p102 p... 271 6e-72 AB209612-1|BAD92849.1| 418|Homo sapiens minichromosome maintena... 270 1e-71 X62153-1|CAA44078.2| 808|Homo sapiens P1.h protein protein. 270 2e-71 BC003509-1|AAH03509.2| 808|Homo sapiens minichromosome maintena... 270 2e-71 BC001626-1|AAH01626.1| 808|Homo sapiens minichromosome maintena... 270 2e-71 AY621074-1|AAT27321.1| 808|Homo sapiens MCM3 minichromosome mai... 270 2e-71 AY032603-1|AAK56392.1| 676|Homo sapiens cervical cancer proto-o... 270 2e-71 AL034343-1|CAB75298.1| 808|Homo sapiens MCM3 minichromosome mai... 270 2e-71 AK222586-1|BAD96306.1| 808|Homo sapiens minichromosome maintena... 270 2e-71 U63630-1|AAC52018.1| 712|Homo sapiens MCM4 protein. 258 7e-68 X74796-1|CAA52803.1| 617|Homo sapiens p85Mcm protein protein. 252 5e-66 D55716-1|BAA09534.1| 719|Homo sapiens P1cdc47 protein. 252 5e-66 D28480-1|BAA05839.1| 543|Homo sapiens hMCM2 protein. 252 5e-66 BC013375-1|AAH13375.1| 719|Homo sapiens minichromosome maintena... 252 5e-66 D21063-1|BAA04642.1| 914|Homo sapiens KIAA0030 protein. 247 1e-64 BT009734-1|AAP88736.1| 895|Homo sapiens MCM2 minichromosome mai... 247 1e-64 BC030131-1|AAH30131.2| 808|Homo sapiens MCM2 protein protein. 247 1e-64 BC017490-1|AAH17490.2| 904|Homo sapiens minichromosome maintena... 247 1e-64 BC014272-1|AAH14272.2| 904|Homo sapiens minichromosome maintena... 247 1e-64 BC007938-1|AAH07938.2| 904|Homo sapiens minichromosome maintena... 247 1e-64 BC007670-1|AAH07670.2| 904|Homo sapiens minichromosome maintena... 247 1e-64 AY675259-1|AAT70723.1| 904|Homo sapiens MCM2 minichromosome mai... 247 1e-64 BC006165-1|AAH06165.3| 904|Homo sapiens minichromosome maintena... 246 3e-64 BC017258-1|AAH17258.2| 904|Homo sapiens minichromosome maintena... 244 1e-63 D83987-1|BAA12177.1| 895|Homo sapiens huMCM2 protein. 243 2e-63 X67334-1|CAA47749.1| 892|Homo sapiens polypeptide BM28 protein. 225 5e-58 BC101057-1|AAI01058.1| 840|Homo sapiens MCM8 protein protein. 225 5e-58 BC101056-1|AAI01057.1| 840|Homo sapiens minichromosome maintena... 225 5e-58 BC080656-1|AAH80656.1| 840|Homo sapiens minichromosome maintena... 225 5e-58 BC008830-1|AAH08830.2| 735|Homo sapiens MCM8 protein protein. 225 5e-58 AL035461-6|CAB55276.2| 840|Homo sapiens MCM8 minichromosome mai... 225 5e-58 AK027644-1|BAB55260.1| 603|Homo sapiens protein ( Homo sapiens ... 225 5e-58 AJ439063-1|CAD27750.1| 840|Homo sapiens minichromosome maintena... 225 5e-58 AY007130-1|AAG01994.1| 351|Homo sapiens protein ( Homo sapiens ... 223 3e-57 AY158211-1|AAO21222.1| 824|Homo sapiens MCM8 isoform protein. 209 3e-53 AL035461-7|CAI23480.1| 824|Homo sapiens MCM8 minichromosome mai... 209 3e-53 AK160378-1|BAD18721.1| 450|Homo sapiens FLJ00323 protein protein. 195 6e-49 BC101055-1|AAI01056.1| 880|Homo sapiens MCM8 protein protein. 190 2e-47 BC000300-1|AAH00300.2| 362|Homo sapiens MCM2 protein protein. 167 1e-40 BC101054-1|AAI01055.1| 793|Homo sapiens MCM8 protein protein. 156 3e-37 U67284-1|AAB48165.1| 181|Homo sapiens homolog of S. pombe mis5 ... 143 3e-33 AL132874-5|CAI42607.1| 451|Homo sapiens protein ( an). ).). 85 1e-15 BC031658-1|AAH31658.1| 391|Homo sapiens minichromosome maintena... 78 1e-13 AL132874-4|CAI42606.1| 156|Homo sapiens protein ( Human DNA seq... 78 1e-13 BC009398-1|AAH09398.1| 389|Homo sapiens MCM7 protein protein. 53 5e-06 AL034343-2|CAD92644.1| 328|Homo sapiens MCM3 minichromosome mai... 46 7e-04 U09584-1|AAA92281.1| 351|Homo sapiens PL6 protein protein. 33 3.0 CR457020-1|CAG33301.1| 351|Homo sapiens PL6 protein. 33 3.0 BC017367-1|AAH17367.1| 351|Homo sapiens transmembrane protein 1... 33 3.0 BC011948-1|AAH11948.1| 351|Homo sapiens transmembrane protein 1... 33 3.0 AC002481-1|AAB67308.1| 247|Homo sapiens PL6 protein, unknown fu... 33 3.0 CR457191-1|CAG33472.1| 303|Homo sapiens MRPL1 protein. 32 6.9 BC104483-1|AAI04484.1| 495|Homo sapiens SUV420H1 protein protein. 32 6.9 BC103498-1|AAI03499.1| 885|Homo sapiens suppressor of variegati... 32 6.9 BC099714-1|AAH99714.1| 885|Homo sapiens suppressor of variegati... 32 6.9 BC098121-1|AAH98121.1| 471|Homo sapiens SUV420H1 protein protein. 32 6.9 BC032595-1|AAH32595.1| 303|Homo sapiens mitochondrial ribosomal... 32 6.9 BC017765-1|AAH17765.1| 302|Homo sapiens Unknown (protein for IM... 32 6.9 BC015109-1|AAH15109.1| 303|Homo sapiens mitochondrial ribosomal... 32 6.9 BC014356-1|AAH14356.1| 303|Homo sapiens mitochondrial ribosomal... 32 6.9 BC012933-1|AAH12933.1| 414|Homo sapiens SUV420H1 protein protein. 32 6.9 AK000046-1|BAA90905.1| 414|Homo sapiens protein ( Homo sapiens ... 32 6.9 AC011999-1|AAY15028.1| 35|Homo sapiens unknown protein. 32 6.9 AB049474-1|BAB40180.1| 303|Homo sapiens mitochondrial ribosomal... 32 6.9 >D84557-1|BAA12699.1| 821|Homo sapiens HsMcm6 protein. Length = 821 Score = 975 bits (2414), Expect = 0.0 Identities = 500/820 (60%), Positives = 616/820 (75%), Gaps = 49/820 (5%) Query: 12 QVKDEVGIRCQKLFQDFLEEFKE-DNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLA 70 +V+DEV +CQKLF DFLEEF+ D EIKY + A+EL++PE +TL VSF D+E++NQ L+ Sbjct: 17 EVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLS 76 Query: 71 TTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKI 130 TTI EE+YR+YP+L RA+ ++ E + KD YV+F D+PTRHK+RELT+++I Sbjct: 77 TTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDF-----YVAFQDLPTRHKIRELTSSRI 131 Query: 131 GTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPTICRNPVCANRRRF 173 G L RISGQ+VRTHPVHPELV GTF YT P ICRNPVCANRRRF Sbjct: 132 GLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRRRF 191 Query: 174 MLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVV 233 +LD +KS FVDFQK+RIQETQAELPRG IPRSLEVILRAEAVES QAGD+ DFTGTLIVV Sbjct: 192 LLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVV 251 Query: 234 PDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFG 293 PDV LS PG+RAE +R + + EGI+GL+ALGVR+L Y+ FLAC V + RFG Sbjct: 252 PDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFG 311 Query: 294 TAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLM 353 EL + T E ++ QMT KEW+KV+EMS+D+NLY+NL TSLFP+IHGN+EVKRGVLLM Sbjct: 312 GKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLM 371 Query: 354 LFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTA 413 LFGGV KTT EGT+LRGDINVCIVGDPSTAKSQ LK V E +PRAVYTSGKASSAAGLTA Sbjct: 372 LFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTA 431 Query: 414 AVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRA 473 AVVRDEES +FVIEAGALMLADNGVCCIDEFDKMD DQVAIHEAMEQQTIS+ KAGV+A Sbjct: 432 AVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKA 491 Query: 474 TLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARK 533 TLNARTSILAAANPI G YDR+KSL+QN+ LS PIMSRFDLFFIL+DE +E+ DYAIAR+ Sbjct: 492 TLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARR 551 Query: 534 IVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYY-XXXXXXXXXXXX 592 IVDLH EES D VYS DD+ RY+ FAR FKP I++E+ +VE Y Sbjct: 552 IVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTK 611 Query: 593 XXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEP 652 WRITVRQLESM+RL+E +A+MHC V P HV EA+RLLNKSIIRVE PD++LD++E Sbjct: 612 SSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEE- 670 Query: 653 QCEPSMDVDQDEP--NGTAETPS------------NGDSAPKKKLALSFEEYKSLSNMLV 698 E M+VD+ NG A++P+ N +SAPK L L F EY +SN++V Sbjct: 671 --EIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEYCRISNLIV 728 Query: 699 VYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLM 758 +++RK S + +S +V+WYL+++ + +I+SE+EL+ +K ++EKVI RL Sbjct: 729 LHLRK-----VEEEEDESALKRSELVNWYLKEI--ESEIDSEEELINKKRIIEKVIHRLT 781 Query: 759 YHDQVIIPLSTTGLRGTQKSSEQDIEDDPLLVVHPNYVVD 798 ++D V+I L+ GL+G+ + SE E+DP LVV+PNY+++ Sbjct: 782 HYDHVLIELTQAGLKGSTEGSE-SYEEDPYLVVNPNYLLE 820 >BC032374-1|AAH32374.1| 821|Homo sapiens minichromosome maintenance complex component 6 protein. Length = 821 Score = 975 bits (2414), Expect = 0.0 Identities = 500/820 (60%), Positives = 616/820 (75%), Gaps = 49/820 (5%) Query: 12 QVKDEVGIRCQKLFQDFLEEFKE-DNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLA 70 +V+DEV +CQKLF DFLEEF+ D EIKY + A+EL++PE +TL VSF D+E++NQ L+ Sbjct: 17 EVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLS 76 Query: 71 TTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKI 130 TTI EE+YR+YP+L RA+ ++ E + KD YV+F D+PTRHK+RELT+++I Sbjct: 77 TTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDF-----YVAFQDLPTRHKIRELTSSRI 131 Query: 131 GTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPTICRNPVCANRRRF 173 G L RISGQ+VRTHPVHPELV GTF YT P ICRNPVCANRRRF Sbjct: 132 GLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRRRF 191 Query: 174 MLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVV 233 +LD +KS FVDFQK+RIQETQAELPRG IPRSLEVILRAEAVES QAGD+ DFTGTLIVV Sbjct: 192 LLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVV 251 Query: 234 PDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFG 293 PDV LS PG+RAE +R + + EGI+GL+ALGVR+L Y+ FLAC V + RFG Sbjct: 252 PDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFG 311 Query: 294 TAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLM 353 EL + T E ++ QMT KEW+KV+EMS+D+NLY+NL TSLFP+IHGN+EVKRGVLLM Sbjct: 312 GKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLM 371 Query: 354 LFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTA 413 LFGGV KTT EGT+LRGDINVCIVGDPSTAKSQ LK V E +PRAVYTSGKASSAAGLTA Sbjct: 372 LFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTA 431 Query: 414 AVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRA 473 AVVRDEES +FVIEAGALMLADNGVCCIDEFDKMD DQVAIHEAMEQQTIS+ KAGV+A Sbjct: 432 AVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKA 491 Query: 474 TLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARK 533 TLNARTSILAAANPI G YDR+KSL+QN+ LS PIMSRFDLFFIL+DE +E+ DYAIAR+ Sbjct: 492 TLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARR 551 Query: 534 IVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYY-XXXXXXXXXXXX 592 IVDLH EES D VYS DD+ RY+ FAR FKP I++E+ +VE Y Sbjct: 552 IVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTK 611 Query: 593 XXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEP 652 WRITVRQLESM+RL+E +A+MHC V P HV EA+RLLNKSIIRVE PD++LD++E Sbjct: 612 SSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEE- 670 Query: 653 QCEPSMDVDQDEP--NGTAETPS------------NGDSAPKKKLALSFEEYKSLSNMLV 698 E M+VD+ NG A++P+ N +SAPK L L F EY +SN++V Sbjct: 671 --EIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEYCRISNLIV 728 Query: 699 VYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLM 758 +++RK S + +S +V+WYL+++ + +I+SE+EL+ +K ++EKVI RL Sbjct: 729 LHLRK-----VEEEEDESALKRSELVNWYLKEI--ESEIDSEEELINKKRIIEKVIHRLT 781 Query: 759 YHDQVIIPLSTTGLRGTQKSSEQDIEDDPLLVVHPNYVVD 798 ++D V+I L+ GL+G+ + SE E+DP LVV+PNY+++ Sbjct: 782 HYDHVLIELTQAGLKGSTEGSE-SYEEDPYLVVNPNYLLE 820 >AY220757-1|AAO26043.1| 821|Homo sapiens MCM6 minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevi protein. Length = 821 Score = 975 bits (2414), Expect = 0.0 Identities = 500/820 (60%), Positives = 616/820 (75%), Gaps = 49/820 (5%) Query: 12 QVKDEVGIRCQKLFQDFLEEFKE-DNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLA 70 +V+DEV +CQKLF DFLEEF+ D EIKY + A+EL++PE +TL VSF D+E++NQ L+ Sbjct: 17 EVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLS 76 Query: 71 TTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKI 130 TTI EE+YR+YP+L RA+ ++ E + KD YV+F D+PTRHK+RELT+++I Sbjct: 77 TTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDF-----YVAFQDLPTRHKIRELTSSRI 131 Query: 131 GTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPTICRNPVCANRRRF 173 G L RISGQ+VRTHPVHPELV GTF YT P ICRNPVCANRRRF Sbjct: 132 GLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRRRF 191 Query: 174 MLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVV 233 +LD +KS FVDFQK+RIQETQAELPRG IPRSLEVILRAEAVES QAGD+ DFTGTLIVV Sbjct: 192 LLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVV 251 Query: 234 PDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFG 293 PDV LS PG+RAE +R + + EGI+GL+ALGVR+L Y+ FLAC V + RFG Sbjct: 252 PDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFG 311 Query: 294 TAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLM 353 EL + T E ++ QMT KEW+KV+EMS+D+NLY+NL TSLFP+IHGN+EVKRGVLLM Sbjct: 312 GKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLM 371 Query: 354 LFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTA 413 LFGGV KTT EGT+LRGDINVCIVGDPSTAKSQ LK V E +PRAVYTSGKASSAAGLTA Sbjct: 372 LFGGVPKTTGEGTSLRGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTA 431 Query: 414 AVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRA 473 AVVRDEES +FVIEAGALMLADNGVCCIDEFDKMD DQVAIHEAMEQQTIS+ KAGV+A Sbjct: 432 AVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKA 491 Query: 474 TLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARK 533 TLNARTSILAAANPI G YDR+KSL+QN+ LS PIMSRFDLFFIL+DE +E+ DYAIAR+ Sbjct: 492 TLNARTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARR 551 Query: 534 IVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYY-XXXXXXXXXXXX 592 IVDLH EES D VYS DD+ RY+ FAR FKP I++E+ +VE Y Sbjct: 552 IVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTK 611 Query: 593 XXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEP 652 WRITVRQLESM+RL+E +A+MHC V P HV EA+RLLNKSIIRVE PD++LD++E Sbjct: 612 SSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEE- 670 Query: 653 QCEPSMDVDQDEP--NGTAETPS------------NGDSAPKKKLALSFEEYKSLSNMLV 698 E M+VD+ NG A++P+ N +SAPK L L F EY +SN++V Sbjct: 671 --EIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEYCRISNLIV 728 Query: 699 VYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLM 758 +++RK S + +S +V+WYL+++ + +I+SE+EL+ +K ++EKVI RL Sbjct: 729 LHLRK-----VEEEEDESALKRSELVNWYLKEI--ESEIDSEEELINKKRIIEKVIHRLT 781 Query: 759 YHDQVIIPLSTTGLRGTQKSSEQDIEDDPLLVVHPNYVVD 798 ++D V+I L+ GL+G+ + SE E+DP LVV+PNY+++ Sbjct: 782 HYDHVLIELTQAGLKGSTEGSE-SYEEDPYLVVNPNYLLE 820 >U46838-1|AAC50766.1| 821|Homo sapiens p105MCM protein. Length = 821 Score = 954 bits (2362), Expect = 0.0 Identities = 491/820 (59%), Positives = 607/820 (74%), Gaps = 49/820 (5%) Query: 12 QVKDEVGIRCQKLFQDFLEEFKE-DNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLA 70 +V+DEV +CQKLF DFLEEF+ D EIKY + A+EL++PE +TL VSF D+E++NQ L+ Sbjct: 17 EVRDEVAEKCQKLFLDFLEEFQSSDGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLS 76 Query: 71 TTIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKI 130 TTI EE+YR+YP+L RA+ ++ E + KD YV+F D+PTRHK+RELT+++I Sbjct: 77 TTIQEEFYRVYPYLCRALKTFVKDRKEIPLAKDF-----YVAFQDLPTRHKIRELTSSRI 131 Query: 131 GTLIRISGQIVRTHPVHPELVQGTF-----------------YTIPTICRNPVCANRRRF 173 G L RISGQ+VRTHPVHPELV GTF YT P ICRNPVCANRRRF Sbjct: 132 GLLTRISGQVVRTHPVHPELVSGTFLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRRRF 191 Query: 174 MLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVV 233 +LD +KS FVDFQK+RIQETQAELPRG IPRSLEVILRAEAVES QAGD+ DFTGTLIVV Sbjct: 192 LLDTNKSRFVDFQKVRIQETQAELPRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVV 251 Query: 234 PDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFG 293 PDV LS PG+RAE +R + + EGI+GL+ALGVR+L Y+ FLAC V + RFG Sbjct: 252 PDVSKLSTPGARAETNSRVSGVDGYETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFG 311 Query: 294 TAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLM 353 EL + T E ++ QMT KEW+KV+EMS+D+NLY+NL TSLFP+IHGN+EVKRGVLLM Sbjct: 312 GKELRDEEQTAESIKNQMTVKEWEKVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLM 371 Query: 354 LFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTA 413 LFGGV+K GDINVCIVGDPSTAKSQ LK V E +PRAVYTSGKASSAAGLTA Sbjct: 372 LFGGVSKDNRRRDLSSGDINVCIVGDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTA 431 Query: 414 AVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRA 473 AVVRDEES +FVIEAGALMLADNGVCCIDEFDKMD DQVAIHEAMEQQTIS+ KAGV+A Sbjct: 432 AVVRDEESHEFVIEAGALMLADNGVCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKA 491 Query: 474 TLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARK 533 TLN RTSILAAANPI G YDR+KSL+QN+ LS PIMSRFDLFFIL+DE +E+ DYAIAR+ Sbjct: 492 TLNTRTSILAAANPISGHYDRSKSLKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARR 551 Query: 534 IVDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYY-XXXXXXXXXXXX 592 IVDLH EES D VYS DD+ RY+ FAR FKP I++E+ +VE Y Sbjct: 552 IVDLHSRIEESIDRVYSLDDIRRYLLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTK 611 Query: 593 XXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEP 652 WRITVRQLESM+RL+E +A+MHC V P HV EA+RLLNKSIIRVE PD++LD++E Sbjct: 612 SSWRITVRQLESMIRLSEAMARMHCCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEE- 670 Query: 653 QCEPSMDVDQDEP--NGTAETPS------------NGDSAPKKKLALSFEEYKSLSNMLV 698 E M+VD+ NG A++P+ N +SAPK L L F EY +SN++V Sbjct: 671 --EIQMEVDEGAGGINGHADSPAPVNGINGYNEDINQESAPKASLRLGFSEYCRISNLIV 728 Query: 699 VYMRKXXXXXXXXXXXSSGMHKSAVVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLM 758 +++RK S + +S +V+WYL+++ + +I+SE+EL+ +K ++EKVI RL Sbjct: 729 LHLRK-----VEEEEDESALKRSELVNWYLKEI--ESEIDSEEELINKKRIIEKVIHRLT 781 Query: 759 YHDQVIIPLSTTGLRGTQKSSEQDIEDDPLLVVHPNYVVD 798 ++D V+I + GL+G+ + SE E+DP LVV+PNY+++ Sbjct: 782 HYDHVLIEPTQAGLKGSTEGSE-SYEEDPYLVVNPNYLLE 820 >AC011893-4|AAX88925.1| 785|Homo sapiens unknown protein. Length = 785 Score = 947 bits (2343), Expect = 0.0 Identities = 485/796 (60%), Positives = 597/796 (75%), Gaps = 48/796 (6%) Query: 35 DNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPFLNRAILNYILS 94 D EIKY + A+EL++PE +TL VSF D+E++NQ L+TTI EE+YR+YP+L RA+ ++ Sbjct: 5 DGEIKYLQLAEELIRPERNTLVVSFVDLEQFNQQLSTTIQEEFYRVYPYLCRALKTFVKD 64 Query: 95 LAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGT 154 E + KD YV+F D+PTRHK+RELT+++IG L RISGQ+VRTHPVHPELV GT Sbjct: 65 RKEIPLAKDF-----YVAFQDLPTRHKIRELTSSRIGLLTRISGQVVRTHPVHPELVSGT 119 Query: 155 F-----------------YTIPTICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAEL 197 F YT P ICRNPVCANRRRF+LD +KS FVDFQK+RIQETQAEL Sbjct: 120 FLCLDCQTVIRDVEQQFKYTQPNICRNPVCANRRRFLLDTNKSRFVDFQKVRIQETQAEL 179 Query: 198 PRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANE 257 PRG IPRSLEVILRAEAVES QAGD+ DFTGTLIVVPDV LS PG+RAE +R + Sbjct: 180 PRGSIPRSLEVILRAEAVESAQAGDKCDFTGTLIVVPDVSKLSTPGARAETNSRVSGVDG 239 Query: 258 GQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWD 317 + EGI+GL+ALGVR+L Y+ FLAC V + RFG EL + T E ++ QMT KEW+ Sbjct: 240 YETEGIRGLRALGVRDLSYRLVFLACCVAPTNPRFGGKELRDEEQTAESIKNQMTVKEWE 299 Query: 318 KVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIV 377 KV+EMS+D+NLY+NL TSLFP+IHGN+EVKRGVLLMLFGGV KTT EGT+LRGDINVCIV Sbjct: 300 KVFEMSQDKNLYHNLCTSLFPTIHGNDEVKRGVLLMLFGGVPKTTGEGTSLRGDINVCIV 359 Query: 378 GDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNG 437 GDPSTAKSQ LK V E +PRAVYTSGKASSAAGLTAAVVRDEES +FVIEAGALMLADNG Sbjct: 360 GDPSTAKSQFLKHVEEFSPRAVYTSGKASSAAGLTAAVVRDEESHEFVIEAGALMLADNG 419 Query: 438 VCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKS 497 VCCIDEFDKMD DQVAIHEAMEQQTIS+ KAGV+ATLNARTSILAAANPI G YDR+KS Sbjct: 420 VCCIDEFDKMDVRDQVAIHEAMEQQTISITKAGVKATLNARTSILAAANPISGHYDRSKS 479 Query: 498 LQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLLRY 557 L+QN+ LS PIMSRFDLFFIL+DE +E+ DYAIAR+IVDLH EES D VYS DD+ RY Sbjct: 480 LKQNINLSAPIMSRFDLFFILVDECNEVTDYAIARRIVDLHSRIEESIDRVYSLDDIRRY 539 Query: 558 IAFARSFKPVITEEAGKLLVEYY-XXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMH 616 + FAR FKP I++E+ +VE Y WRITVRQLESM+RL+E +A+MH Sbjct: 540 LLFARQFKPKISKESEDFIVEQYKHLRQRDGSGVTKSSWRITVRQLESMIRLSEAMARMH 599 Query: 617 CSGHVTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEP--NGTAETPS- 673 C V P HV EA+RLLNKSIIRVE PD++LD++E E M+VD+ NG A++P+ Sbjct: 600 CCDEVQPKHVKEAFRLLNKSIIRVETPDVNLDQEE---EIQMEVDEGAGGINGHADSPAP 656 Query: 674 -----------NGDSAPKKKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHKSA 722 N +SAPK L L F EY +SN++V+++RK S + +S Sbjct: 657 VNGINGYNEDINQESAPKASLRLGFSEYCRISNLIVLHLRK-----VEEEEDESALKRSE 711 Query: 723 VVSWYLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLRGTQKSSEQD 782 +V+WYL+++ + +I+SE+EL+ +K ++EKVI RL ++D V+I L+ GL+G+ + SE Sbjct: 712 LVNWYLKEI--ESEIDSEEELINKKRIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSE-S 768 Query: 783 IEDDPLLVVHPNYVVD 798 E+DP LVV+PNY+++ Sbjct: 769 YEEDPYLVVNPNYLLE 784 >X74794-1|CAA52801.1| 923|Homo sapiens P1 Cdc21 protein protein. Length = 923 Score = 278 bits (682), Expect = 5e-74 Identities = 204/636 (32%), Positives = 324/636 (50%), Gaps = 47/636 (7%) Query: 21 CQKLFQDFLEEF------KEDN------EIKYEKHAKELLKPELSTLEVSFDDVEKYNQN 68 C++ FQ FL+ F +E+N E Y + E+ L V+ + ++ +++N Sbjct: 222 CKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEQFLNVNCEHIKSFDKN 281 Query: 69 LATTIIEEYYRIYPFLNRAILNYILS-LAETGMKKDLQDKECYVSFVDVPTRHKVRELTT 127 L +I + P + A+ ++ ++ +Q + F + T++ +R L Sbjct: 282 LYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRP----FNALKTKN-MRNLNP 336 Query: 128 AKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDF-Q 186 I LI ISG ++RT + PE+ + F C+ VCA+ R +D + Sbjct: 337 EDIDQLITISGMVIRTSQLIPEMQEAFFQ-----CQ--VCAHTTRVEMDRGRIAEPSVCG 389 Query: 187 KIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRA 246 + + A + + ++I E+ E + AG T L D+ PG R Sbjct: 390 RCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQT-PHTVILFAHNDLVDKVQPGDRV 448 Query: 247 EITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTED 306 +T + + +K++ YKT + + R A+ H L E Sbjct: 449 NVTGIYRAVPIRVNPRVSNVKSV------YKT-----HIDVIHYRKTDAKR-LHGLDEEA 496 Query: 307 MRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT---TI 363 +K ++K + + E+SR ++Y L ++L PSI+ + ++K+G+LL LFGG K T Sbjct: 497 EQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTG 556 Query: 364 EGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD 423 G R +IN+ + GDP T+KSQLL+ V + PR YTSGK SSA GLTA V++D E+ Sbjct: 557 RGK-FRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQ 615 Query: 424 FVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILA 483 V++ GAL+L+DNG+CCIDEFDKM+ + +HE MEQQT+S+AKAG+ LNARTS+LA Sbjct: 616 LVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLA 675 Query: 484 AANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE 543 AANPI +++ K+ +N+ L ++SRFDL F+++D E D +A +V L+ EE Sbjct: 676 AANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVALYYQSEE 735 Query: 544 -SYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQ 601 + + + L YIA+A S P ++EEA + L+E Y RQ Sbjct: 736 QAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVS--AYPRQ 793 Query: 602 LESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637 LES++RLAE AK+ S V V EA RL +++ Sbjct: 794 LESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREAL 829 >BC031061-1|AAH31061.1| 863|Homo sapiens minichromosome maintenance complex component 4 protein. Length = 863 Score = 278 bits (681), Expect = 6e-74 Identities = 202/636 (31%), Positives = 325/636 (51%), Gaps = 47/636 (7%) Query: 21 CQKLFQDFLEEFKEDNEIKYEKHAKELLKP-------ELST-----LEVSFDDVEKYNQN 68 C++ FQ FL+ F + + E ++ +P E++ L V+ + ++ +++N Sbjct: 162 CKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKN 221 Query: 69 LATTIIEEYYRIYPFLNRAILNYILS-LAETGMKKDLQDKECYVSFVDVPTRHKVRELTT 127 L +I + P + A+ ++ ++ +Q + F + T++ +R L Sbjct: 222 LYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRP----FNALKTKN-MRNLNP 276 Query: 128 AKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDF-Q 186 I LI ISG ++RT + PE+ + F C+ VCA+ R +D + Sbjct: 277 EDIDQLITISGMVIRTSQLIPEMQEAFFQ-----CQ--VCAHTTRVEMDRGRIAEPSVCG 329 Query: 187 KIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRA 246 + + A + + ++I E+ E + AG T L D+ PG R Sbjct: 330 RCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQT-PHTVILFAHNDLVDKVQPGDRV 388 Query: 247 EITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTED 306 +T + + +K++ YKT + + R A+ H L E Sbjct: 389 NVTGIYRAVPIRVNPRVSNVKSV------YKT-----HIDVIHYRKTDAKR-LHGLDEEA 436 Query: 307 MRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT---TI 363 +K ++K + + E+SR ++Y L ++L PSI+ + ++K+G+LL LFGG K T Sbjct: 437 EQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTG 496 Query: 364 EGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD 423 G R +IN+ + GDP T+KSQLL+ V + PR YTSGK SSA GLTA V++D E+ Sbjct: 497 RGK-FRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQ 555 Query: 424 FVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILA 483 V++ GAL+L+DNG+CCIDEFDKM+ + +HE MEQQT+S+AKAG+ LNARTS+LA Sbjct: 556 LVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLA 615 Query: 484 AANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE 543 AANPI +++ K+ +N+ L ++SRFDL F+++D E D +A +V L+ EE Sbjct: 616 AANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVALYYQSEE 675 Query: 544 -SYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQ 601 + + + L YIA+A S P ++EEA + L+E Y RQ Sbjct: 676 QAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVS--AYPRQ 733 Query: 602 LESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637 LES++RLAE AK+ S V V EA RL +++ Sbjct: 734 LESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREAL 769 >AY588245-1|AAS83108.1| 863|Homo sapiens MCM4 minichromosome maintenance deficient 4 (S. cerevisiae) protein. Length = 863 Score = 278 bits (681), Expect = 6e-74 Identities = 202/636 (31%), Positives = 325/636 (51%), Gaps = 47/636 (7%) Query: 21 CQKLFQDFLEEFKEDNEIKYEKHAKELLKP-------ELST-----LEVSFDDVEKYNQN 68 C++ FQ FL+ F + + E ++ +P E++ L V+ + ++ +++N Sbjct: 162 CKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKN 221 Query: 69 LATTIIEEYYRIYPFLNRAILNYILS-LAETGMKKDLQDKECYVSFVDVPTRHKVRELTT 127 L +I + P + A+ ++ ++ +Q + F + T++ +R L Sbjct: 222 LYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRP----FNALKTKN-MRNLNP 276 Query: 128 AKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDF-Q 186 I LI ISG ++RT + PE+ + F C+ VCA+ R +D + Sbjct: 277 EDIDQLITISGMVIRTSQLIPEMQEAFFQ-----CQ--VCAHTTRVEMDRGRIAEPSVCG 329 Query: 187 KIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRA 246 + + A + + ++I E+ E + AG T L D+ PG R Sbjct: 330 RCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQT-PHTVILFAHNDLVDKVQPGDRV 388 Query: 247 EITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTED 306 +T + + +K++ YKT + + R A+ H L E Sbjct: 389 NVTGIYRAVPIRVNPRVSNVKSV------YKT-----HIDVIHYRKTDAKR-LHGLDEEA 436 Query: 307 MRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT---TI 363 +K ++K + + E+SR ++Y L ++L PSI+ + ++K+G+LL LFGG K T Sbjct: 437 EQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTG 496 Query: 364 EGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD 423 G R +IN+ + GDP T+KSQLL+ V + PR YTSGK SSA GLTA V++D E+ Sbjct: 497 RGK-FRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQ 555 Query: 424 FVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILA 483 V++ GAL+L+DNG+CCIDEFDKM+ + +HE MEQQT+S+AKAG+ LNARTS+LA Sbjct: 556 LVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLA 615 Query: 484 AANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE 543 AANPI +++ K+ +N+ L ++SRFDL F+++D E D +A +V L+ EE Sbjct: 616 AANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLMLDPQDEAYDRRLAHHLVALYYQSEE 675 Query: 544 -SYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQ 601 + + + L YIA+A S P ++EEA + L+E Y RQ Sbjct: 676 QAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIEAYVDMRKIGSSRGMVS--AYPRQ 733 Query: 602 LESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSI 637 LES++RLAE AK+ S V V EA RL +++ Sbjct: 734 LESLIRLAEAHAKVRLSNKVEAIDVEEAKRLHREAL 769 >D83986-1|BAA12176.1| 733|Homo sapiens huMCM5 protein. Length = 733 Score = 277 bits (678), Expect = 1e-73 Identities = 211/675 (31%), Positives = 333/675 (49%), Gaps = 85/675 (12%) Query: 5 DTYATQSQVKDEVGIRCQKLFQDFLEEFKEDNE-----IKYEKHAKELLKPELSTLEVSF 59 D A + Q + + Q+ F++FL +++ + KY K +EV Sbjct: 18 DAQADEGQARKS---QLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEM 74 Query: 60 DDVEKYNQNLATTIIE---EYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDV 116 +D+ ++++LA + + E+ ++ + + + + +G ++ LQD + + Sbjct: 75 EDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSG-EEVLQDIQVMLKSDAS 133 Query: 117 PTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF--------------------Y 156 P+ +R L + + L++I G I+ V + + + Y Sbjct: 134 PS--SIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGY 191 Query: 157 TIPTICRNPVCANRRRFMLDA-----DKSVFVDFQKIRIQETQAELPRGCIPRSLEVILR 211 +P C N A R + LD DK VDFQ +++QE +P G +PR +++ Sbjct: 192 ALPRKC-NTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCD 250 Query: 212 AEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGV 271 + V G+R T++ + + + SR R ++ +G+ Sbjct: 251 RYLCDKVVPGNRV----TIMGIYSIKKFGLTTSRG----RDRVG-------------VGI 289 Query: 272 RELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 R + + + R F A P + E+ R+ ++ N+Y Sbjct: 290 RSSYIRVLGIQVDTDGSGRSFAGAVSPQEE---EEFRR------------LAALPNVYEV 334 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391 + S+ PSI G ++K+ + +LFGG K +G T RGDIN+ ++GDP TAKSQLLK V Sbjct: 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFV 394 Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451 + +P VYTSGK SSAAGLTA+V+RD S +F++E GA++LAD GV CIDEFDKM D Sbjct: 395 EKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDD 454 Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511 +VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+D K + N+ P I+SR Sbjct: 455 RVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSR 513 Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL---RYIAFAR-SFKPV 567 FD+ FI+ DE +E+ D +A+ ++ LH + V DL ++IA+ R P Sbjct: 514 FDMIFIVKDEHNEVRDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPR 573 Query: 568 ITEEAGKLLVEYY----XXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTP 623 ++ EA + L Y ITVRQLE++VR+AE ++KM T Sbjct: 574 LSAEAAEKLKNRYIIMRTGPVSTRGTVTASSIPITVRQLEAIVRIAEALSKMKLQPFATE 633 Query: 624 AHVHEAYRLLNKSII 638 A V EA RL S + Sbjct: 634 ADVEEALRLFQVSTL 648 >X74795-1|CAA52802.2| 734|Homo sapiens P1 Cdc46 protein. Length = 734 Score = 275 bits (675), Expect = 3e-73 Identities = 212/676 (31%), Positives = 333/676 (49%), Gaps = 86/676 (12%) Query: 5 DTYATQSQVKDEVGIRCQKLFQDFLEEFKEDNE-----IKYEKHAKELLKPELSTLEVSF 59 D A + Q + + Q+ F++FL +++ + KY K +EV Sbjct: 18 DAQADEGQARKS---QLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEM 74 Query: 60 DDVEKYNQNLATTIIE---EYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDV 116 +D+ ++++LA + + E+ ++ + + + + +G ++ LQD + + Sbjct: 75 EDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSG-EEVLQDIQVMLKSDAS 133 Query: 117 PTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF--------------------Y 156 P+ +R L + + L++I G I+ V + + + Y Sbjct: 134 PS--SIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGY 191 Query: 157 TIPTICRNPVCANRRRFMLDA-----DKSVFVDFQKIRIQETQAELPRGCIPRSLEVILR 211 +P C N A R + LD DK VDFQ +++QE +P G +PR +++ Sbjct: 192 ALPRKC-NTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCD 250 Query: 212 AEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGV 271 + V G+R T++ + + + SR R ++ +G+ Sbjct: 251 RYLCDKVVPGNRV----TIMGIYSIKKFGLTTSRG----RDRVG-------------VGI 289 Query: 272 RELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 R + + + R F A P + E+ R+ ++ N+Y Sbjct: 290 RSSYIRVLGIQVDTDGSGRSFAGAVSPQEE---EEFRR------------LAALPNVYEV 334 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391 + S+ PSI G ++K+ + +LFGG K +G T RGDIN+ ++GDP TAKSQLLK V Sbjct: 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFV 394 Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451 + +P VYTSGK SSAAGLTA+V+RD S +F++E GA++LAD GV CIDEFDKM D Sbjct: 395 EKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDD 454 Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511 +VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+D K + N+ P I+SR Sbjct: 455 RVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSR 513 Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL---RYIAFAR-SFKPV 567 FD+ FI+ DE +E D +A+ ++ LH + V DL ++IA+ R P Sbjct: 514 FDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPR 573 Query: 568 ITEEAGKLLVEYYXXXXXXXXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHCSGHVT 622 ++ EA + L Y R ITVRQLE++VR+AE ++KM T Sbjct: 574 LSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFAT 633 Query: 623 PAHVHEAYRLLNKSII 638 A V EA RL S + Sbjct: 634 EADVEEALRLFQVSTL 649 >CR456517-1|CAG30403.1| 734|Homo sapiens MCM5 protein. Length = 734 Score = 275 bits (675), Expect = 3e-73 Identities = 212/676 (31%), Positives = 333/676 (49%), Gaps = 86/676 (12%) Query: 5 DTYATQSQVKDEVGIRCQKLFQDFLEEFKEDNE-----IKYEKHAKELLKPELSTLEVSF 59 D A + Q + + Q+ F++FL +++ + KY K +EV Sbjct: 18 DAQADEGQARKS---QLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEM 74 Query: 60 DDVEKYNQNLATTIIE---EYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDV 116 +D+ ++++LA + + E+ ++ + + + + +G ++ LQD + + Sbjct: 75 EDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSG-EEVLQDIQVMLKSDAS 133 Query: 117 PTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF--------------------Y 156 P+ +R L + + L++I G I+ V + + + Y Sbjct: 134 PS--SIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGY 191 Query: 157 TIPTICRNPVCANRRRFMLDA-----DKSVFVDFQKIRIQETQAELPRGCIPRSLEVILR 211 +P C N A R + LD DK VDFQ +++QE +P G +PR +++ Sbjct: 192 ALPRKC-NTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCD 250 Query: 212 AEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGV 271 + V G+R T++ + + + SR R ++ +G+ Sbjct: 251 RYLCDKVVPGNRV----TIMGIYSIKKFGLTTSRG----RDRVG-------------VGI 289 Query: 272 RELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 R + + + R F A P + E+ R+ ++ N+Y Sbjct: 290 RSSYIRVLGIQVDTDGSGRSFAGAVSPQEE---EEFRR------------LAALPNVYEV 334 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391 + S+ PSI G ++K+ + +LFGG K +G T RGDIN+ ++GDP TAKSQLLK V Sbjct: 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFV 394 Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451 + +P VYTSGK SSAAGLTA+V+RD S +F++E GA++LAD GV CIDEFDKM D Sbjct: 395 EKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDD 454 Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511 +VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+D K + N+ P I+SR Sbjct: 455 RVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSR 513 Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL---RYIAFAR-SFKPV 567 FD+ FI+ DE +E D +A+ ++ LH + V DL ++IA+ R P Sbjct: 514 FDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPR 573 Query: 568 ITEEAGKLLVEYYXXXXXXXXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHCSGHVT 622 ++ EA + L Y R ITVRQLE++VR+AE ++KM T Sbjct: 574 LSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFAT 633 Query: 623 PAHVHEAYRLLNKSII 638 A V EA RL S + Sbjct: 634 EADVEEALRLFQVSTL 649 >BC000142-1|AAH00142.1| 734|Homo sapiens minichromosome maintenance complex component 5 protein. Length = 734 Score = 275 bits (675), Expect = 3e-73 Identities = 212/676 (31%), Positives = 333/676 (49%), Gaps = 86/676 (12%) Query: 5 DTYATQSQVKDEVGIRCQKLFQDFLEEFKEDNE-----IKYEKHAKELLKPELSTLEVSF 59 D A + Q + + Q+ F++FL +++ + KY K +EV Sbjct: 18 DAQADEGQARKS---QLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEM 74 Query: 60 DDVEKYNQNLATTIIE---EYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDV 116 +D+ ++++LA + + E+ ++ + + + + +G ++ LQD + + Sbjct: 75 EDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSG-EEVLQDIQVMLKSDAS 133 Query: 117 PTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF--------------------Y 156 P+ +R L + + L++I G I+ V + + + Y Sbjct: 134 PS--SIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGY 191 Query: 157 TIPTICRNPVCANRRRFMLDA-----DKSVFVDFQKIRIQETQAELPRGCIPRSLEVILR 211 +P C N A R + LD DK VDFQ +++QE +P G +PR +++ Sbjct: 192 ALPRKC-NTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCD 250 Query: 212 AEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGV 271 + V G+R T++ + + + SR R ++ +G+ Sbjct: 251 RYLCDKVVPGNRV----TIMGIYSIKKFGLTTSRG----RDRVG-------------VGI 289 Query: 272 RELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 R + + + R F A P + E+ R+ ++ N+Y Sbjct: 290 RSSYIRVLGIQVDTDGSGRSFAGAVSPQEE---EEFRR------------LAALPNVYEV 334 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391 + S+ PSI G ++K+ + +LFGG K +G T RGDIN+ ++GDP TAKSQLLK V Sbjct: 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFV 394 Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451 + +P VYTSGK SSAAGLTA+V+RD S +F++E GA++LAD GV CIDEFDKM D Sbjct: 395 EKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDD 454 Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511 +VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+D K + N+ P I+SR Sbjct: 455 RVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSR 513 Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL---RYIAFAR-SFKPV 567 FD+ FI+ DE +E D +A+ ++ LH + V DL ++IA+ R P Sbjct: 514 FDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPR 573 Query: 568 ITEEAGKLLVEYYXXXXXXXXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHCSGHVT 622 ++ EA + L Y R ITVRQLE++VR+AE ++KM T Sbjct: 574 LSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFAT 633 Query: 623 PAHVHEAYRLLNKSII 638 A V EA RL S + Sbjct: 634 EADVEEALRLFQVSTL 649 >AY212028-1|AAO21127.1| 734|Homo sapiens MCM5 minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevis protein. Length = 734 Score = 275 bits (675), Expect = 3e-73 Identities = 212/676 (31%), Positives = 333/676 (49%), Gaps = 86/676 (12%) Query: 5 DTYATQSQVKDEVGIRCQKLFQDFLEEFKEDNE-----IKYEKHAKELLKPELSTLEVSF 59 D A + Q + + Q+ F++FL +++ + KY K +EV Sbjct: 18 DAQADEGQARKS---QLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEM 74 Query: 60 DDVEKYNQNLATTIIE---EYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDV 116 +D+ ++++LA + + E+ ++ + + + + +G ++ LQD + + Sbjct: 75 EDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSG-EEVLQDIQVMLKSDAS 133 Query: 117 PTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF--------------------Y 156 P+ +R L + + L++I G I+ V + + + Y Sbjct: 134 PS--SIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGY 191 Query: 157 TIPTICRNPVCANRRRFMLDA-----DKSVFVDFQKIRIQETQAELPRGCIPRSLEVILR 211 +P C N A R + LD DK VDFQ +++QE +P G +PR +++ Sbjct: 192 ALPRKC-NTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCD 250 Query: 212 AEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGV 271 + V G+R T++ + + + SR R ++ +G+ Sbjct: 251 RYLCDKVVPGNRV----TIMGIYSIKKFGLTTSRG----RDRVG-------------VGI 289 Query: 272 RELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 R + + + R F A P + E+ R+ ++ N+Y Sbjct: 290 RSSYIRVLGIQVDTDGSGRSFAGAVSPQEE---EEFRR------------LAALPNVYEV 334 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391 + S+ PSI G ++K+ + +LFGG K +G T RGDIN+ ++GDP TAKSQLLK V Sbjct: 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFV 394 Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451 + +P VYTSGK SSAAGLTA+V+RD S +F++E GA++LAD GV CIDEFDKM D Sbjct: 395 EKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDD 454 Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511 +VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+D K + N+ P I+SR Sbjct: 455 RVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSR 513 Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL---RYIAFAR-SFKPV 567 FD+ FI+ DE +E D +A+ ++ LH + V DL ++IA+ R P Sbjct: 514 FDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPR 573 Query: 568 ITEEAGKLLVEYYXXXXXXXXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHCSGHVT 622 ++ EA + L Y R ITVRQLE++VR+AE ++KM T Sbjct: 574 LSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFAT 633 Query: 623 PAHVHEAYRLLNKSII 638 A V EA RL S + Sbjct: 634 EADVEEALRLFQVSTL 649 >BC003656-1|AAH03656.1| 734|Homo sapiens minichromosome maintenance complex component 5 protein. Length = 734 Score = 275 bits (674), Expect = 5e-73 Identities = 184/497 (37%), Positives = 264/497 (53%), Gaps = 52/497 (10%) Query: 156 YTIPTICRNPVCANRRRFMLDA-----DKSVFVDFQKIRIQETQAELPRGCIPRSLEVIL 210 Y +P C N A R + LD DK VDFQ +++QE +P G +PR +++ Sbjct: 191 YALPRKC-NTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYC 249 Query: 211 RAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALG 270 + V G+R T++ + + + SR R ++ +G Sbjct: 250 DRYLCDKVVPGNRV----TIMGIYSIKKFGLTTSRG----RDRVG-------------VG 288 Query: 271 VRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYN 330 +R + + + R F A P + E+ R+ ++ N+Y Sbjct: 289 IRSSYIRVLGIQVDTDGSGRSFAGAVSPQEE---EEFRR------------LAALPNVYE 333 Query: 331 NLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQ 390 + S+ PSI G ++K+ + +LFGG K +G T RGDIN+ ++GDP TAKSQLLK Sbjct: 334 VISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKF 393 Query: 391 VSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPG 450 V + +P VYTSGK SSAAGLTA+V+RD S +F++E GA++LAD GV CIDEFDKM Sbjct: 394 VEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMRED 453 Query: 451 DQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMS 510 D+VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+D K + N+ P I+S Sbjct: 454 DRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILS 512 Query: 511 RFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL---RYIAFAR-SFKP 566 RFD+ FI+ DE +E D +A+ ++ LH + V DL ++IA+ R P Sbjct: 513 RFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGP 572 Query: 567 VITEEAGKLLVEYYXXXXXXXXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHCSGHV 621 ++ EA + L Y R ITVRQLE++VR+AE ++KM Sbjct: 573 RLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFA 632 Query: 622 TPAHVHEAYRLLNKSII 638 T A V EA RL S + Sbjct: 633 TEADVEEALRLFQVSTL 649 >AK223323-1|BAD97043.1| 734|Homo sapiens minichromosome maintenance deficient protein 5 variant protein. Length = 734 Score = 275 bits (674), Expect = 5e-73 Identities = 184/497 (37%), Positives = 264/497 (53%), Gaps = 52/497 (10%) Query: 156 YTIPTICRNPVCANRRRFMLDA-----DKSVFVDFQKIRIQETQAELPRGCIPRSLEVIL 210 Y +P C N A R + LD DK VDFQ +++QE +P G +PR +++ Sbjct: 191 YALPRKC-NTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYC 249 Query: 211 RAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALG 270 + V G+R T++ + + + SR R ++ +G Sbjct: 250 DRYLCDKVVPGNRV----TIMGIYSIKKFGLTTSRG----RDRVG-------------VG 288 Query: 271 VRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYN 330 +R + + + R F A P + E+ R+ ++ N+Y Sbjct: 289 IRSSYIRVLGIQVDTDGSGRSFAGAVSPQEE---EEFRR------------LAALPNVYE 333 Query: 331 NLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQ 390 + S+ PSI G ++K+ + +LFGG K +G T RGDIN+ ++GDP TAKSQLLK Sbjct: 334 VISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKF 393 Query: 391 VSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPG 450 V + +P VYTSGK SSAAGLTA+V+RD S +F++E GA++LAD GV CIDEFDKM Sbjct: 394 VEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMRED 453 Query: 451 DQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMS 510 D+VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+D K + N+ P I+S Sbjct: 454 DRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILS 512 Query: 511 RFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL---RYIAFAR-SFKP 566 RFD+ FI+ DE +E D +A+ ++ LH + V DL ++IA+ R P Sbjct: 513 RFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGP 572 Query: 567 VITEEAGKLLVEYYXXXXXXXXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHCSGHV 621 ++ EA + L Y R ITVRQLE++VR+AE ++KM Sbjct: 573 RLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFA 632 Query: 622 TPAHVHEAYRLLNKSII 638 T A V EA RL S + Sbjct: 633 TEADVEEALRLFQVSTL 649 >Z82244-2|CAB05110.1| 733|Homo sapiens MCM5 minichromosome maintenance deficient 5, cellr) protein. Length = 733 Score = 271 bits (665), Expect = 6e-72 Identities = 212/676 (31%), Positives = 333/676 (49%), Gaps = 87/676 (12%) Query: 5 DTYATQSQVKDEVGIRCQKLFQDFLEEFKEDNE-----IKYEKHAKELLKPELSTLEVSF 59 D A + Q + + Q+ F++FL +++ + KY K +EV Sbjct: 18 DAQADEGQARKS---QLQRRFKEFLRQYRVGTDRTGFTFKYRDELKRHYNLGEYWIEVEM 74 Query: 60 DDVEKYNQNLATTIIE---EYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFVDV 116 +D+ ++++LA + + E+ ++ + + + + +G ++ LQD + + Sbjct: 75 EDLASFDEDLADYLYKQPAEHLQLLEEAAKEVADEVTRPRPSG-EEVLQDIQVMLKSDAS 133 Query: 117 PTRHKVRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF--------------------Y 156 P+ +R L + + L++I G I+ V + + + Y Sbjct: 134 PS--SIRSLKSDMMSHLVKIPGIIIAASAVRAKATRISIQCRSCRNTLTNIAMRPGLEGY 191 Query: 157 TIPTICRNPVCANRRRFMLDA-----DKSVFVDFQKIRIQETQAELPRGCIPRSLEVILR 211 +P C N A R + LD DK VDFQ +++QE +P G +PR +++ Sbjct: 192 ALPRKC-NTDQAGRPKCPLDPYFIMPDKCKCVDFQTLKLQELPDAVPHGEMPRHMQLYCD 250 Query: 212 AEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGV 271 + V G+R T++ + + + SR R ++ +G+ Sbjct: 251 RYLCDKVVPGNRV----TIMGIYSIKKFGLTTSRG----RDRVG-------------VGI 289 Query: 272 RELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 R + + + R F A P + E+ R+ ++ N+Y Sbjct: 290 RSSYIRVLGIQVDTDGSGRSFAGAVSPQEE---EEFRR------------LAALPNVYEV 334 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQV 391 + S+ PSI G ++K+ + +LFGG K +G T RGDIN+ ++GDP TAKSQLLK V Sbjct: 335 ISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQLLKFV 394 Query: 392 SEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGD 451 + +P VYTSGK SSAAGLTA+V+RD S +F++E GA++LAD GV CIDEFDKM D Sbjct: 395 EKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDKMREDD 454 Query: 452 QVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSR 511 +VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+D K + N+ P I+SR Sbjct: 455 RVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMPTILSR 513 Query: 512 FDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL---RYIAFAR-SFKPV 567 FD+ FI+ DE +E D +A+ ++ LH + V DL ++IA+ R P Sbjct: 514 FDMIFIVKDEHNEERD-MLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRVKCGPR 572 Query: 568 ITEEAGKLLVEYYXXXXXXXXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHCSGHVT 622 ++ EA + L Y R ITVRQLE++VR+AE ++KM T Sbjct: 573 LSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKLQPFAT 632 Query: 623 PAHVHEAYRLLNKSII 638 A V EA RL S + Sbjct: 633 EADVEEALRLFQVSTL 648 >D38073-1|BAA07267.1| 808|Homo sapiens hRlf beta subunit (p102 protein) protein. Length = 808 Score = 271 bits (665), Expect = 6e-72 Identities = 185/549 (33%), Positives = 296/549 (53%), Gaps = 72/549 (13%) Query: 13 VKDEVGIR-CQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71 V D+V +R Q+ + DFL++ +ED I Y+ +EL+ L V+ +D+ + N+ A Sbjct: 6 VLDDVELREAQRDYLDFLDD-EEDQGI-YQSKVRELISDNQYRLIVNVNDLRRKNEKRAN 63 Query: 72 TIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFV-DVPTRH-KVRELTTAK 129 ++ + RA+ +++ S+ T K Q +E YV ++H R LT+ Sbjct: 64 RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120 Query: 130 IGTLIRISGQIVRTHPVHPELVQGTFYT-------------IPTICRNPVCA-----NRR 171 + ++ + G + + V P++V+ Y + T+ P + + Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180 Query: 172 RFMLDADK--SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229 L+ + SV+ D Q I IQE + P G +PRS++VIL + V+ AGDR GT Sbjct: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKANAGDRVQVVGT 240 Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289 +PG + T+ T ++T +AC+V+ +S Sbjct: 241 Y--------RCLPGKKGGYTSGT-----------------------FRTVLIACNVKQMS 269 Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349 + A+ P+ + ED+ K K + +R +++++ L SL PSIHG++ VK+ Sbjct: 270 K---DAQ-PS--FSAEDIAKI-------KKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKA 316 Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409 +L +L GGV + G+ +RGDIN+ ++GDPS AKSQLL+ V PRA+ T+G+ SS Sbjct: 317 ILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376 Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469 GLTAAV D+E+ + +EAGA++LAD GV CIDEFDKM D+ AIHE MEQ +++AKA Sbjct: 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKA 436 Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529 G+ A LNAR S+LAAANP+ GRYD+ K+ +N+ L ++SRFDL FI++D+ D Sbjct: 437 GIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDRE 496 Query: 530 IARKIVDLH 538 I+ ++ +H Sbjct: 497 ISDHVLRMH 505 Score = 45.6 bits (103), Expect = 7e-04 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 7/134 (5%) Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYX--XXXXXXXXXXXXX 594 LH K++ V S + +YI A+ KPV+T+E+ + E Y Sbjct: 552 LHGTKKKKEKMV-SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART 610 Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN----KSIIRVEQPDIHLDED 650 +T R LE+++RLA AK S V EA L+ K ++ E+ ED Sbjct: 611 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED 670 Query: 651 EPQCEPSMDVDQDE 664 E + E + Q++ Sbjct: 671 ESETEDEEEKSQED 684 >AB209612-1|BAD92849.1| 418|Homo sapiens minichromosome maintenance deficient protein 5 variant protein. Length = 418 Score = 270 bits (662), Expect = 1e-71 Identities = 149/321 (46%), Positives = 200/321 (62%), Gaps = 10/321 (3%) Query: 327 NLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQ 386 N+Y + S+ PSI G ++K+ + +LFGG K +G T RGDIN+ ++GDP TAKSQ Sbjct: 47 NVYEVISKSIAPSIFGGTDMKKAIACLLFGGSRKRLPDGLTRRGDINLLMLGDPGTAKSQ 106 Query: 387 LLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDK 446 LLK V + +P VYTSGK SSAAGLTA+V+RD S +F++E GA++LAD GV CIDEFDK Sbjct: 107 LLKFVEKCSPIGVYTSGKGSSAAGLTASVMRDPSSRNFIMEGGAMVLADGGVVCIDEFDK 166 Query: 447 MDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSP 506 M D+VAIHEAMEQQTIS+AKAG+ TLN+R S+LAAAN + GR+D K + N+ P Sbjct: 167 MREDDRVAIHEAMEQQTISIAKAGITTTLNSRCSVLAAANSVFGRWDETKG-EDNIDFMP 225 Query: 507 PIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL---RYIAFAR- 562 I+SRFD+ FI+ DE +E D +A+ ++ LH + V DL ++IA+ R Sbjct: 226 TILSRFDMIFIVKDEHNEERDVMLAKHVITLHVSALTQTQAVEGEIDLAKLKKFIAYCRV 285 Query: 563 SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWR-----ITVRQLESMVRLAEGVAKMHC 617 P ++ EA + L Y R ITVRQLE++VR+AE ++KM Sbjct: 286 KCGPRLSAEAAEKLKNRYIIMRSGARQHERDSDRRSSIPITVRQLEAIVRIAEALSKMKL 345 Query: 618 SGHVTPAHVHEAYRLLNKSII 638 T A V EA RL S + Sbjct: 346 QPFATEADVEEALRLFQVSTL 366 >X62153-1|CAA44078.2| 808|Homo sapiens P1.h protein protein. Length = 808 Score = 270 bits (661), Expect = 2e-71 Identities = 184/549 (33%), Positives = 296/549 (53%), Gaps = 72/549 (13%) Query: 13 VKDEVGIR-CQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71 V D+V +R Q+ + DFL++ +ED I Y+ +EL+ L V+ +D+ + N+ A Sbjct: 6 VLDDVELREAQRDYLDFLDD-EEDQGI-YQSKVRELISDNQYRLIVNVNDLRRKNEKRAN 63 Query: 72 TIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFV-DVPTRH-KVRELTTAK 129 ++ + RA+ +++ S+ T K Q +E YV ++H R LT+ Sbjct: 64 RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120 Query: 130 IGTLIRISGQIVRTHPVHPELVQGTFYT-------------IPTICRNPVCA-----NRR 171 + ++ + G + + V P++V+ Y + T+ P + + Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180 Query: 172 RFMLDADK--SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229 L+ + SV+ D Q I IQE + P G +PRS++VIL + V+ + GDR GT Sbjct: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT 240 Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289 +PG + T+ T ++T +AC+V+ +S Sbjct: 241 Y--------RCLPGKKGGYTSGT-----------------------FRTVLIACNVKQMS 269 Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349 + A+ P+ + ED+ K K + +R +++++ L SL PSIHG++ VK+ Sbjct: 270 K---DAQ-PS--FSAEDIAKI-------KKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKA 316 Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409 +L +L GGV + G+ +RGDIN+ ++GDPS AKSQLL+ V PRA+ T+G+ SS Sbjct: 317 ILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376 Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469 GLTAAV D+E+ + +EAGA++LAD GV CIDEFDKM D+ AIHE MEQ +++AKA Sbjct: 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKA 436 Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529 G+ A LNAR S+LAAANP+ GRYD+ K+ +N+ L ++SRFDL FI++D+ D Sbjct: 437 GIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDRE 496 Query: 530 IARKIVDLH 538 I+ ++ +H Sbjct: 497 ISDHVLRMH 505 Score = 45.6 bits (103), Expect = 7e-04 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 7/134 (5%) Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYX--XXXXXXXXXXXXX 594 LH K++ V S + +YI A+ KPV+T+E+ + E Y Sbjct: 552 LHGTKKKKEKMV-SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART 610 Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN----KSIIRVEQPDIHLDED 650 +T R LE+++RLA AK S V EA L+ K ++ E+ ED Sbjct: 611 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED 670 Query: 651 EPQCEPSMDVDQDE 664 E + E + Q++ Sbjct: 671 ESETEDEEEKSQED 684 >BC003509-1|AAH03509.2| 808|Homo sapiens minichromosome maintenance complex component 3 protein. Length = 808 Score = 270 bits (661), Expect = 2e-71 Identities = 184/549 (33%), Positives = 296/549 (53%), Gaps = 72/549 (13%) Query: 13 VKDEVGIR-CQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71 V D+V +R Q+ + DFL++ +ED I Y+ +EL+ L V+ +D+ + N+ A Sbjct: 6 VLDDVELREAQRDYLDFLDD-EEDQGI-YQSKVRELISDNQYRLIVNVNDLRRKNEKRAN 63 Query: 72 TIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFV-DVPTRH-KVRELTTAK 129 ++ + RA+ +++ S+ T K Q +E YV ++H R LT+ Sbjct: 64 RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120 Query: 130 IGTLIRISGQIVRTHPVHPELVQGTFYT-------------IPTICRNPVCA-----NRR 171 + ++ + G + + V P++V+ Y + T+ P + + Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180 Query: 172 RFMLDADK--SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229 L+ + SV+ D Q I IQE + P G +PRS++VIL + V+ + GDR GT Sbjct: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT 240 Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289 +PG + T+ T ++T +AC+V+ +S Sbjct: 241 Y--------RCLPGKKGGYTSGT-----------------------FRTVLIACNVKQMS 269 Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349 + A+ P+ + ED+ K K + +R +++++ L SL PSIHG++ VK+ Sbjct: 270 K---DAQ-PS--FSAEDIAKI-------KKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKA 316 Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409 +L +L GGV + G+ +RGDIN+ ++GDPS AKSQLL+ V PRA+ T+G+ SS Sbjct: 317 ILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376 Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469 GLTAAV D+E+ + +EAGA++LAD GV CIDEFDKM D+ AIHE MEQ +++AKA Sbjct: 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKA 436 Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529 G+ A LNAR S+LAAANP+ GRYD+ K+ +N+ L ++SRFDL FI++D+ D Sbjct: 437 GIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDRE 496 Query: 530 IARKIVDLH 538 I+ ++ +H Sbjct: 497 ISDHVLRMH 505 Score = 45.6 bits (103), Expect = 7e-04 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 7/134 (5%) Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYX--XXXXXXXXXXXXX 594 LH K++ V S + +YI A+ KPV+T+E+ + E Y Sbjct: 552 LHGTKKKKEKMV-SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART 610 Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN----KSIIRVEQPDIHLDED 650 +T R LE+++RLA AK S V EA L+ K ++ E+ ED Sbjct: 611 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED 670 Query: 651 EPQCEPSMDVDQDE 664 E + E + Q++ Sbjct: 671 ESETEDEEEKSQED 684 >BC001626-1|AAH01626.1| 808|Homo sapiens minichromosome maintenance complex component 3 protein. Length = 808 Score = 270 bits (661), Expect = 2e-71 Identities = 184/549 (33%), Positives = 296/549 (53%), Gaps = 72/549 (13%) Query: 13 VKDEVGIR-CQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71 V D+V +R Q+ + DFL++ +ED I Y+ +EL+ L V+ +D+ + N+ A Sbjct: 6 VLDDVELREAQRDYLDFLDD-EEDQGI-YQSKVRELISDNQYRLIVNVNDLRRKNEKRAN 63 Query: 72 TIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFV-DVPTRH-KVRELTTAK 129 ++ + RA+ +++ S+ T K Q +E YV ++H R LT+ Sbjct: 64 RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120 Query: 130 IGTLIRISGQIVRTHPVHPELVQGTFYT-------------IPTICRNPVCA-----NRR 171 + ++ + G + + V P++V+ Y + T+ P + + Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180 Query: 172 RFMLDADK--SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229 L+ + SV+ D Q I IQE + P G +PRS++VIL + V+ + GDR GT Sbjct: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT 240 Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289 +PG + T+ T ++T +AC+V+ +S Sbjct: 241 Y--------RCLPGKKGGYTSGT-----------------------FRTVLIACNVKQMS 269 Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349 + A+ P+ + ED+ K K + +R +++++ L SL PSIHG++ VK+ Sbjct: 270 K---DAQ-PS--FSAEDIAKI-------KKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKA 316 Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409 +L +L GGV + G+ +RGDIN+ ++GDPS AKSQLL+ V PRA+ T+G+ SS Sbjct: 317 ILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376 Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469 GLTAAV D+E+ + +EAGA++LAD GV CIDEFDKM D+ AIHE MEQ +++AKA Sbjct: 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKA 436 Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529 G+ A LNAR S+LAAANP+ GRYD+ K+ +N+ L ++SRFDL FI++D+ D Sbjct: 437 GIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDRE 496 Query: 530 IARKIVDLH 538 I+ ++ +H Sbjct: 497 ISDHVLRMH 505 Score = 45.6 bits (103), Expect = 7e-04 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 7/134 (5%) Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYX--XXXXXXXXXXXXX 594 LH K++ V S + +YI A+ KPV+T+E+ + E Y Sbjct: 552 LHGTKKKKEKMV-SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART 610 Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN----KSIIRVEQPDIHLDED 650 +T R LE+++RLA AK S V EA L+ K ++ E+ ED Sbjct: 611 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED 670 Query: 651 EPQCEPSMDVDQDE 664 E + E + Q++ Sbjct: 671 ESETEDEEEKSQED 684 >AY621074-1|AAT27321.1| 808|Homo sapiens MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) protein. Length = 808 Score = 270 bits (661), Expect = 2e-71 Identities = 184/549 (33%), Positives = 296/549 (53%), Gaps = 72/549 (13%) Query: 13 VKDEVGIR-CQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71 V D+V +R Q+ + DFL++ +ED I Y+ +EL+ L V+ +D+ + N+ A Sbjct: 6 VLDDVELREAQRDYLDFLDD-EEDQGI-YQSKVRELISDNQYRLIVNVNDLRRKNEKRAN 63 Query: 72 TIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFV-DVPTRH-KVRELTTAK 129 ++ + RA+ +++ S+ T K Q +E YV ++H R LT+ Sbjct: 64 RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120 Query: 130 IGTLIRISGQIVRTHPVHPELVQGTFYT-------------IPTICRNPVCA-----NRR 171 + ++ + G + + V P++V+ Y + T+ P + + Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180 Query: 172 RFMLDADK--SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229 L+ + SV+ D Q I IQE + P G +PRS++VIL + V+ + GDR GT Sbjct: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT 240 Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289 +PG + T+ T ++T +AC+V+ +S Sbjct: 241 Y--------RCLPGKKGGYTSGT-----------------------FRTVLIACNVKQMS 269 Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349 + A+ P+ + ED+ K K + +R +++++ L SL PSIHG++ VK+ Sbjct: 270 K---DAQ-PS--FSAEDIAKI-------KKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKA 316 Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409 +L +L GGV + G+ +RGDIN+ ++GDPS AKSQLL+ V PRA+ T+G+ SS Sbjct: 317 ILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376 Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469 GLTAAV D+E+ + +EAGA++LAD GV CIDEFDKM D+ AIHE MEQ +++AKA Sbjct: 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKA 436 Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529 G+ A LNAR S+LAAANP+ GRYD+ K+ +N+ L ++SRFDL FI++D+ D Sbjct: 437 GIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDRE 496 Query: 530 IARKIVDLH 538 I+ ++ +H Sbjct: 497 ISDHVLRMH 505 Score = 45.6 bits (103), Expect = 7e-04 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 7/134 (5%) Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYX--XXXXXXXXXXXXX 594 LH K++ V S + +YI A+ KPV+T+E+ + E Y Sbjct: 552 LHGTKKKKEKMV-SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART 610 Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN----KSIIRVEQPDIHLDED 650 +T R LE+++RLA AK S V EA L+ K ++ E+ ED Sbjct: 611 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED 670 Query: 651 EPQCEPSMDVDQDE 664 E + E + Q++ Sbjct: 671 ESETEDEEEKSQED 684 >AY032603-1|AAK56392.1| 676|Homo sapiens cervical cancer proto-oncogene 5 protein. Length = 676 Score = 270 bits (661), Expect = 2e-71 Identities = 184/549 (33%), Positives = 296/549 (53%), Gaps = 72/549 (13%) Query: 13 VKDEVGIR-CQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71 V D+V +R Q+ + DFL++ +ED I Y+ +EL+ L V+ +D+ + N+ A Sbjct: 6 VLDDVELREAQRDYLDFLDD-EEDQGI-YQSKVRELISDNQYRLIVNVNDLRRKNEKRAN 63 Query: 72 TIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFV-DVPTRH-KVRELTTAK 129 ++ + RA+ +++ S+ T K Q +E YV ++H R LT+ Sbjct: 64 RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120 Query: 130 IGTLIRISGQIVRTHPVHPELVQGTFYT-------------IPTICRNPVCA-----NRR 171 + ++ + G + + V P++V+ Y + T+ P + + Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180 Query: 172 RFMLDADK--SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229 L+ + SV+ D Q I IQE + P G +PRS++VIL + V+ + GDR GT Sbjct: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT 240 Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289 +PG + T+ T ++T +AC+V+ +S Sbjct: 241 Y--------RCLPGKKGGYTSGT-----------------------FRTVLIACNVKQMS 269 Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349 + A+ P+ + ED+ K K + +R +++++ L SL PSIHG++ VK+ Sbjct: 270 K---DAQ-PS--FSAEDIAKI-------KKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKA 316 Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409 +L +L GGV + G+ +RGDIN+ ++GDPS AKSQLL+ V PRA+ T+G+ SS Sbjct: 317 ILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376 Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469 GLTAAV D+E+ + +EAGA++LAD GV CIDEFDKM D+ AIHE MEQ +++AKA Sbjct: 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKA 436 Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529 G+ A LNAR S+LAAANP+ GRYD+ K+ +N+ L ++SRFDL FI++D+ D Sbjct: 437 GIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDRE 496 Query: 530 IARKIVDLH 538 I+ ++ +H Sbjct: 497 ISDHVLRMH 505 Score = 43.2 bits (97), Expect = 0.004 Identities = 35/125 (28%), Positives = 53/125 (42%), Gaps = 7/125 (5%) Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYX--XXXXXXXXXXXXX 594 LH K++ V S + +YI A+ KPV+T+E+ + E Y Sbjct: 552 LHGTKKKKEKMV-SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART 610 Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN----KSIIRVEQPDIHLDED 650 +T R LE+++RLA AK S V EA L+ K ++ E+ ED Sbjct: 611 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED 670 Query: 651 EPQCE 655 E + E Sbjct: 671 ESETE 675 >AL034343-1|CAB75298.1| 808|Homo sapiens MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) protein. Length = 808 Score = 270 bits (661), Expect = 2e-71 Identities = 184/549 (33%), Positives = 296/549 (53%), Gaps = 72/549 (13%) Query: 13 VKDEVGIR-CQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71 V D+V +R Q+ + DFL++ +ED I Y+ +EL+ L V+ +D+ + N+ A Sbjct: 6 VLDDVELREAQRDYLDFLDD-EEDQGI-YQSKVRELISDNQYRLIVNVNDLRRKNEKRAN 63 Query: 72 TIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFV-DVPTRH-KVRELTTAK 129 ++ + RA+ +++ S+ T K Q +E YV ++H R LT+ Sbjct: 64 RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120 Query: 130 IGTLIRISGQIVRTHPVHPELVQGTFYT-------------IPTICRNPVCA-----NRR 171 + ++ + G + + V P++V+ Y + T+ P + + Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180 Query: 172 RFMLDADK--SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229 L+ + SV+ D Q I IQE + P G +PRS++VIL + V+ + GDR GT Sbjct: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT 240 Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289 +PG + T+ T ++T +AC+V+ +S Sbjct: 241 Y--------RCLPGKKGGYTSGT-----------------------FRTVLIACNVKQMS 269 Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349 + A+ P+ + ED+ K K + +R +++++ L SL PSIHG++ VK+ Sbjct: 270 K---DAQ-PS--FSAEDIAKI-------KKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKA 316 Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409 +L +L GGV + G+ +RGDIN+ ++GDPS AKSQLL+ V PRA+ T+G+ SS Sbjct: 317 ILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376 Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469 GLTAAV D+E+ + +EAGA++LAD GV CIDEFDKM D+ AIHE MEQ +++AKA Sbjct: 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKA 436 Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529 G+ A LNAR S+LAAANP+ GRYD+ K+ +N+ L ++SRFDL FI++D+ D Sbjct: 437 GIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDRE 496 Query: 530 IARKIVDLH 538 I+ ++ +H Sbjct: 497 ISDHVLRMH 505 Score = 45.6 bits (103), Expect = 7e-04 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 7/134 (5%) Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYX--XXXXXXXXXXXXX 594 LH K++ V S + +YI A+ KPV+T+E+ + E Y Sbjct: 552 LHGTKKKKEKMV-SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART 610 Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN----KSIIRVEQPDIHLDED 650 +T R LE+++RLA AK S V EA L+ K ++ E+ ED Sbjct: 611 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED 670 Query: 651 EPQCEPSMDVDQDE 664 E + E + Q++ Sbjct: 671 ESETEDEEEKSQED 684 >AK222586-1|BAD96306.1| 808|Homo sapiens minichromosome maintenance protein 3 variant protein. Length = 808 Score = 270 bits (661), Expect = 2e-71 Identities = 184/549 (33%), Positives = 296/549 (53%), Gaps = 72/549 (13%) Query: 13 VKDEVGIR-CQKLFQDFLEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLAT 71 V D+V +R Q+ + DFL++ +ED I Y+ +EL+ L V+ +D+ + N+ A Sbjct: 6 VLDDVELREAQRDYLDFLDD-EEDQGI-YQSKVRELISDNQYRLIVNVNDLRRKNEKRAN 63 Query: 72 TIIEEYYRIYPFLNRAILNYILSLAETGMKKDLQDKECYVSFV-DVPTRH-KVRELTTAK 129 ++ + RA+ +++ S+ T K Q +E YV ++H R LT+ Sbjct: 64 RLLNNAFEELVAFQRALKDFVASIDATYAK---QYEEFYVGLEGSFGSKHVSPRTLTSCF 120 Query: 130 IGTLIRISGQIVRTHPVHPELVQGTFYT-------------IPTICRNPVCA-----NRR 171 + ++ + G + + V P++V+ Y + T+ P + + Sbjct: 121 LSCVVCVEGIVTKCSLVRPKVVRSVHYCPATKKTIERRYSDLTTLVAFPSSSVYPTKDEE 180 Query: 172 RFMLDADK--SVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGT 229 L+ + SV+ D Q I IQE + P G +PRS++VIL + V+ + GDR GT Sbjct: 181 NNPLETEYGLSVYKDHQTITIQEMPEKAPAGQLPRSVDVILDDDLVDKAKPGDRVQVVGT 240 Query: 230 LIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVS 289 +PG + T+ T ++T +AC+V+ +S Sbjct: 241 Y--------RCLPGKKGGYTSGT-----------------------FRTVLIACNVKQMS 269 Query: 290 RRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRG 349 + A+ P+ + ED+ K K + +R +++++ L SL PSIHG++ VK+ Sbjct: 270 K---DAQ-PS--FSAEDIAKI-------KKFSKTRSKDIFDQLAKSLAPSIHGHDYVKKA 316 Query: 350 VLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAA 409 +L +L GGV + G+ +RGDIN+ ++GDPS AKSQLL+ V PRA+ T+G+ SS Sbjct: 317 ILCLLLGGVERDLENGSHIRGDINILLIGDPSVAKSQLLRYVLCTAPRAIPTTGRGSSGV 376 Query: 410 GLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKA 469 GLTAAV D+E+ + +EAGA++LAD GV CIDEFDKM D+ AIHE MEQ +++AKA Sbjct: 377 GLTAAVTTDQETGERRLEAGAMVLADRGVVCIDEFDKMSDMDRTAIHEVMEQGRVTIAKA 436 Query: 470 GVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYA 529 G+ A LNAR S+LAAANP+ GRYD+ K+ +N+ L ++SRFDL FI++D+ D Sbjct: 437 GIHARLNARCSVLAAANPVYGRYDQYKTPMENIGLQDSLLSRFDLLFIMLDQMDPEQDRE 496 Query: 530 IARKIVDLH 538 I+ ++ +H Sbjct: 497 ISDHVLRMH 505 Score = 46.8 bits (106), Expect = 3e-04 Identities = 36/134 (26%), Positives = 58/134 (43%), Gaps = 7/134 (5%) Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYX--XXXXXXXXXXXXX 594 LH K++ + V S + +YI A+ KPV+T+E+ + E Y Sbjct: 552 LHGTKKKKEEMV-SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART 610 Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN----KSIIRVEQPDIHLDED 650 +T R LE+++RLA AK S V EA L+ K ++ E+ ED Sbjct: 611 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED 670 Query: 651 EPQCEPSMDVDQDE 664 E + E + Q++ Sbjct: 671 ESETEDEEEKSQED 684 >U63630-1|AAC52018.1| 712|Homo sapiens MCM4 protein. Length = 712 Score = 258 bits (631), Expect = 7e-68 Identities = 184/577 (31%), Positives = 300/577 (51%), Gaps = 45/577 (7%) Query: 21 CQKLFQDFLEEFKEDNEIKYEKHAKELLKP-------ELST-----LEVSFDDVEKYNQN 68 C++ FQ FL+ F + + E ++ +P E++ L V+ + ++ +++N Sbjct: 162 CKENFQRFLQRFIDPLAKEEENVGIDITEPLYMQRLGEINVIGEPFLNVNCEHIKSFDKN 221 Query: 69 LATTIIEEYYRIYPFLNRAILNYILS-LAETGMKKDLQDKECYVSFVDVPTRHKVRELTT 127 L +I + P + A+ ++ ++ +Q + F + T++ +R L Sbjct: 222 LYRQLISYPQEVIPTFDMAVNEIFFDRYPDSILEHQIQVRP----FNALKTKN-MRNLNP 276 Query: 128 AKIGTLIRISGQIVRTHPVHPELVQGTFYTIPTICRNPVCANRRRFMLDADKSVFVDF-Q 186 I LI ISG ++RT + PE+ + F C+ VCA+ R +D + Sbjct: 277 EDIDQLITISGMVIRTSQLIPEMQEAFFQ-----CQ--VCAHTTRVEMDRGRIAEPSVCG 329 Query: 187 KIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRA 246 + + A + + ++I E+ E + AG T L D+ PG R Sbjct: 330 RCHTTHSMALIHNRSLFSDKQMIKLQESPEDMPAGQT-PHTVILFAHNDLVDKVQPGDRV 388 Query: 247 EITTRTKLANEGQMEGIKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTED 306 +T + + +K++ YKT + + R A+ H L E Sbjct: 389 NVTGIYRAVPIRVNPRVSNVKSV------YKT-----HIDVIHYRKTDAKR-LHGLDEEA 436 Query: 307 MRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKT---TI 363 +K ++K + + E+SR ++Y L ++L PSI+ + ++K+G+LL LFGG K T Sbjct: 437 EQKLFSEKRVELLKELSRKPDIYERLASALAPSIYEHEDIKKGILLQLFGGTRKDFSHTG 496 Query: 364 EGTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFD 423 G R +IN+ + GDP T+KSQLL+ V + PR YTSGK SSA GLTA V++D E+ Sbjct: 497 RGK-FRAEINILLCGDPGTSKSQLLQYVYNLVPRGQYTSGKGSSAVGLTAYVMKDPETRQ 555 Query: 424 FVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILA 483 V++ GAL+L+DNG+CCIDEFDKM+ + +HE MEQQT+S+AKAG+ LNARTS+LA Sbjct: 556 LVLQTGALVLSDNGICCIDEFDKMNESTRSVLHEVMEQQTLSIAKAGIICQLNARTSVLA 615 Query: 484 AANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEE 543 AANPI +++ K+ +N+ L ++SRFDL F+L+D E D +A +V L+ EE Sbjct: 616 AANPIESQWNPKKTTIENIQLPHTLLSRFDLIFLLLDPQDEAYDRRLAHHLVALYYQSEE 675 Query: 544 -SYDCVYSRDDLLRYIAFARS-FKPVITEEAGKLLVE 578 + + + L YIA+A S P ++EEA + L+E Sbjct: 676 QAEEELLDMAVLKDYIAYAHSTIMPRLSEEASQALIE 712 >X74796-1|CAA52803.1| 617|Homo sapiens p85Mcm protein protein. Length = 617 Score = 252 bits (616), Expect = 5e-66 Identities = 132/314 (42%), Positives = 189/314 (60%), Gaps = 4/314 (1%) Query: 325 DRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAK 384 + + Y L S+ P I+G+ +VK+ +LL+L GGV ++ G +RG+IN+C++GDP AK Sbjct: 227 EEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSP-RGMKIRGNINICLMGDPGVAK 285 Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEF 444 SQLL + + PR+ YT+G+ SS GLTAAV+RD S + +E GAL+LAD GVCCIDEF Sbjct: 286 SQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEF 345 Query: 445 DKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVAL 504 DKM D+ AIHE MEQQTIS+AKAG+ TLNAR SILAAANP GRY+ +SL+QN+ L Sbjct: 346 DKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQL 405 Query: 505 SPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL--RYIAFAR 562 ++SRFDL +++ D D +A+ I +H + + D L RYIA R Sbjct: 406 PAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCR 465 Query: 563 SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVT 622 +P++ E + Y + + R L +++RL+ +A++ V Sbjct: 466 EKQPMVPESLADYITAAYVEMRREAWASKDATY-TSARTLLAILRLSTALARLRMVDVVE 524 Query: 623 PAHVHEAYRLLNKS 636 V+EA RL+ S Sbjct: 525 KEDVNEAIRLMEMS 538 Score = 52.8 bits (121), Expect = 5e-06 Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 20/136 (14%) Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF------------YTIPT-----ICRN 164 +RE+ +G L+ + G + R V P++V T+ PT +C + Sbjct: 47 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 106 Query: 165 PVCANRR---RFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAG 221 C R R L S F+ FQ++++QE ++P G IPRS+ V++ E Q G Sbjct: 107 QECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPG 166 Query: 222 DRYDFTGTLIVVPDVG 237 D TG + + G Sbjct: 167 DHVSVTGIFLPILRTG 182 >D55716-1|BAA09534.1| 719|Homo sapiens P1cdc47 protein. Length = 719 Score = 252 bits (616), Expect = 5e-66 Identities = 132/314 (42%), Positives = 189/314 (60%), Gaps = 4/314 (1%) Query: 325 DRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAK 384 + + Y L S+ P I+G+ +VK+ +LL+L GGV ++ G +RG+IN+C++GDP AK Sbjct: 329 EEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSP-RGMKIRGNINICLMGDPGVAK 387 Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEF 444 SQLL + + PR+ YT+G+ SS GLTAAV+RD S + +E GAL+LAD GVCCIDEF Sbjct: 388 SQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEF 447 Query: 445 DKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVAL 504 DKM D+ AIHE MEQQTIS+AKAG+ TLNAR SILAAANP GRY+ +SL+QN+ L Sbjct: 448 DKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQL 507 Query: 505 SPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL--RYIAFAR 562 ++SRFDL +++ D D +A+ I +H + + D L RYIA R Sbjct: 508 PAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCR 567 Query: 563 SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVT 622 +P++ E + Y + + R L +++RL+ +A++ V Sbjct: 568 EKQPMVPESLADYITAAYVEMRREAWASKDATY-TSARTLLAILRLSTALARLRMVDVVE 626 Query: 623 PAHVHEAYRLLNKS 636 V+EA RL+ S Sbjct: 627 KEDVNEAIRLMEMS 640 Score = 52.8 bits (121), Expect = 5e-06 Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 20/136 (14%) Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF------------YTIPT-----ICRN 164 +RE+ +G L+ + G + R V P++V T+ PT +C + Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208 Query: 165 PVCANRR---RFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAG 221 C R R L S F+ FQ++++QE ++P G IPRS+ V++ E Q G Sbjct: 209 QECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPG 268 Query: 222 DRYDFTGTLIVVPDVG 237 D TG + + G Sbjct: 269 DHVSVTGIFLPILRTG 284 >D28480-1|BAA05839.1| 543|Homo sapiens hMCM2 protein. Length = 543 Score = 252 bits (616), Expect = 5e-66 Identities = 132/314 (42%), Positives = 189/314 (60%), Gaps = 4/314 (1%) Query: 325 DRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAK 384 + + Y L S+ P I+G+ +VK+ +LL+L GGV ++ G +RG+IN+C++GDP AK Sbjct: 153 EEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSP-RGMKIRGNINICLMGDPGVAK 211 Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEF 444 SQLL + + PR+ YT+G+ SS GLTAAV+RD S + +E GAL+LAD GVCCIDEF Sbjct: 212 SQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEF 271 Query: 445 DKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVAL 504 DKM D+ AIHE MEQQTIS+AKAG+ TLNAR SILAAANP GRY+ +SL+QN+ L Sbjct: 272 DKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQL 331 Query: 505 SPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL--RYIAFAR 562 ++SRFDL +++ D D +A+ I +H + + D L RYIA R Sbjct: 332 PAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCR 391 Query: 563 SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVT 622 +P++ E + Y + + R L +++RL+ +A++ V Sbjct: 392 EKQPMVPESLADYITAAYVEMRREAWASKDATY-TSARTLLAILRLSTALARLRMVDVVE 450 Query: 623 PAHVHEAYRLLNKS 636 V+EA RL+ S Sbjct: 451 KEDVNEAIRLMEMS 464 Score = 46.8 bits (106), Expect = 3e-04 Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 3/80 (3%) Query: 161 ICRNPVCANRR---RFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVES 217 +C + C R R L S F+ FQ++++QE ++P G IPRS+ V++ E Sbjct: 29 MCPSQECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRI 88 Query: 218 VQAGDRYDFTGTLIVVPDVG 237 Q GD TG + + G Sbjct: 89 AQPGDHVSVTGIFLPILRTG 108 >BC013375-1|AAH13375.1| 719|Homo sapiens minichromosome maintenance complex component 7 protein. Length = 719 Score = 252 bits (616), Expect = 5e-66 Identities = 132/314 (42%), Positives = 189/314 (60%), Gaps = 4/314 (1%) Query: 325 DRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPSTAK 384 + + Y L S+ P I+G+ +VK+ +LL+L GGV ++ G +RG+IN+C++GDP AK Sbjct: 329 EEDFYEKLAASIAPEIYGHEDVKKALLLLLVGGVDQSP-RGMKIRGNINICLMGDPGVAK 387 Query: 385 SQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEF 444 SQLL + + PR+ YT+G+ SS GLTAAV+RD S + +E GAL+LAD GVCCIDEF Sbjct: 388 SQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLEGGALVLADQGVCCIDEF 447 Query: 445 DKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVAL 504 DKM D+ AIHE MEQQTIS+AKAG+ TLNAR SILAAANP GRY+ +SL+QN+ L Sbjct: 448 DKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANPAYGRYNPRRSLEQNIQL 507 Query: 505 SPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDCVYSRDDLL--RYIAFAR 562 ++SRFDL +++ D D +A+ I +H + + D L RYIA R Sbjct: 508 PAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQFEPLDMKLMRRYIAMCR 567 Query: 563 SFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVT 622 +P++ E + Y + + R L +++RL+ +A++ V Sbjct: 568 EKQPMVPESLADYITAAYVEMRREAWASKDATY-TSARTLLAILRLSTALARLRMVDVVE 626 Query: 623 PAHVHEAYRLLNKS 636 V+EA RL+ S Sbjct: 627 KEDVNEAIRLMEMS 640 Score = 52.8 bits (121), Expect = 5e-06 Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 20/136 (14%) Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF------------YTIPT-----ICRN 164 +RE+ +G L+ + G + R V P++V T+ PT +C + Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208 Query: 165 PVCANRR---RFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAG 221 C R R L S F+ FQ++++QE ++P G IPRS+ V++ E Q G Sbjct: 209 QECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPG 268 Query: 222 DRYDFTGTLIVVPDVG 237 D TG + + G Sbjct: 269 DHVSVTGIFLPILRTG 284 >D21063-1|BAA04642.1| 914|Homo sapiens KIAA0030 protein. Length = 914 Score = 247 bits (605), Expect = 1e-64 Identities = 190/642 (29%), Positives = 309/642 (48%), Gaps = 57/642 (8%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 209 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 268 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 269 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 325 Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202 V P+L + P C ++ + + + Q E E I Sbjct: 326 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 379 Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262 ++ + I E+ V AG R + I++ D+ PG E+T +G + Sbjct: 380 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 438 Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322 G + T LA V + EL TD++ + + Sbjct: 439 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 477 Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382 S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +RGDINV + GDP T Sbjct: 478 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGT 537 Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442 AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID Sbjct: 538 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 597 Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502 EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV Sbjct: 598 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 657 Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546 L+ PI+SRFD+ ++ D + D +AR +V H NKEE + Sbjct: 658 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 717 Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600 Y ++ L +YI +A+ P + + + + Y ITVR Sbjct: 718 NTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 775 Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 776 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 817 >BT009734-1|AAP88736.1| 895|Homo sapiens MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae) protein. Length = 895 Score = 247 bits (605), Expect = 1e-64 Identities = 190/642 (29%), Positives = 309/642 (48%), Gaps = 57/642 (8%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 190 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 249 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 250 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 306 Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202 V P+L + P C ++ + + + Q E E I Sbjct: 307 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 360 Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262 ++ + I E+ V AG R + I++ D+ PG E+T +G + Sbjct: 361 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 419 Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322 G + T LA V + EL TD++ + + Sbjct: 420 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 458 Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382 S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +RGDINV + GDP T Sbjct: 459 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGT 518 Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442 AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID Sbjct: 519 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 578 Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502 EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV Sbjct: 579 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 638 Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546 L+ PI+SRFD+ ++ D + D +AR +V H NKEE + Sbjct: 639 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 698 Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600 Y ++ L +YI +A+ P + + + + Y ITVR Sbjct: 699 NTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 756 Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 757 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 798 >BC030131-1|AAH30131.2| 808|Homo sapiens MCM2 protein protein. Length = 808 Score = 247 bits (605), Expect = 1e-64 Identities = 190/642 (29%), Positives = 309/642 (48%), Gaps = 57/642 (8%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 103 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 162 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 163 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 219 Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202 V P+L + P C ++ + + + Q E E I Sbjct: 220 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 273 Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262 ++ + I E+ V AG R + I++ D+ PG E+T +G + Sbjct: 274 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 332 Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322 G + T LA V + EL TD++ + + Sbjct: 333 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 371 Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382 S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +RGDINV + GDP T Sbjct: 372 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGT 431 Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442 AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID Sbjct: 432 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 491 Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502 EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV Sbjct: 492 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 551 Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546 L+ PI+SRFD+ ++ D + D +AR +V H NKEE + Sbjct: 552 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 611 Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600 Y ++ L +YI +A+ P + + + + Y ITVR Sbjct: 612 NTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 669 Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 670 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 711 >BC017490-1|AAH17490.2| 904|Homo sapiens minichromosome maintenance complex component 2 protein. Length = 904 Score = 247 bits (605), Expect = 1e-64 Identities = 190/642 (29%), Positives = 309/642 (48%), Gaps = 57/642 (8%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 258 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 259 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 315 Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202 V P+L + P C ++ + + + Q E E I Sbjct: 316 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 369 Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262 ++ + I E+ V AG R + I++ D+ PG E+T +G + Sbjct: 370 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428 Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322 G + T LA V + EL TD++ + + Sbjct: 429 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 467 Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382 S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +RGDINV + GDP T Sbjct: 468 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGT 527 Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442 AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID Sbjct: 528 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 587 Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502 EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV Sbjct: 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 647 Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546 L+ PI+SRFD+ ++ D + D +AR +V H NKEE + Sbjct: 648 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 707 Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600 Y ++ L +YI +A+ P + + + + Y ITVR Sbjct: 708 NTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 765 Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 766 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 807 >BC014272-1|AAH14272.2| 904|Homo sapiens minichromosome maintenance complex component 2 protein. Length = 904 Score = 247 bits (605), Expect = 1e-64 Identities = 190/642 (29%), Positives = 309/642 (48%), Gaps = 57/642 (8%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 258 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 259 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 315 Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202 V P+L + P C ++ + + + Q E E I Sbjct: 316 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 369 Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262 ++ + I E+ V AG R + I++ D+ PG E+T +G + Sbjct: 370 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428 Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322 G + T LA V + EL TD++ + + Sbjct: 429 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 467 Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382 S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +RGDINV + GDP T Sbjct: 468 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGT 527 Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442 AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID Sbjct: 528 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 587 Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502 EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV Sbjct: 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 647 Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546 L+ PI+SRFD+ ++ D + D +AR +V H NKEE + Sbjct: 648 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 707 Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600 Y ++ L +YI +A+ P + + + + Y ITVR Sbjct: 708 NTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 765 Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 766 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 807 >BC007938-1|AAH07938.2| 904|Homo sapiens minichromosome maintenance complex component 2 protein. Length = 904 Score = 247 bits (605), Expect = 1e-64 Identities = 190/642 (29%), Positives = 309/642 (48%), Gaps = 57/642 (8%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 258 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 259 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 315 Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202 V P+L + P C ++ + + + Q E E I Sbjct: 316 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 369 Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262 ++ + I E+ V AG R + I++ D+ PG E+T +G + Sbjct: 370 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428 Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322 G + T LA V + EL TD++ + + Sbjct: 429 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 467 Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382 S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +RGDINV + GDP T Sbjct: 468 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGT 527 Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442 AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID Sbjct: 528 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 587 Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502 EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV Sbjct: 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 647 Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546 L+ PI+SRFD+ ++ D + D +AR +V H NKEE + Sbjct: 648 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 707 Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600 Y ++ L +YI +A+ P + + + + Y ITVR Sbjct: 708 NTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 765 Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 766 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 807 >BC007670-1|AAH07670.2| 904|Homo sapiens minichromosome maintenance complex component 2 protein. Length = 904 Score = 247 bits (605), Expect = 1e-64 Identities = 190/642 (29%), Positives = 309/642 (48%), Gaps = 57/642 (8%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 258 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 259 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 315 Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202 V P+L + P C ++ + + + Q E E I Sbjct: 316 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 369 Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262 ++ + I E+ V AG R + I++ D+ PG E+T +G + Sbjct: 370 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428 Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322 G + T LA V + EL TD++ + + Sbjct: 429 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 467 Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382 S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +RGDINV + GDP T Sbjct: 468 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGT 527 Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442 AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID Sbjct: 528 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 587 Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502 EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV Sbjct: 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 647 Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546 L+ PI+SRFD+ ++ D + D +AR +V H NKEE + Sbjct: 648 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 707 Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600 Y ++ L +YI +A+ P + + + + Y ITVR Sbjct: 708 NTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 765 Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 766 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 807 >AY675259-1|AAT70723.1| 904|Homo sapiens MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae) protein. Length = 904 Score = 247 bits (605), Expect = 1e-64 Identities = 190/642 (29%), Positives = 309/642 (48%), Gaps = 57/642 (8%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 258 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 259 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 315 Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202 V P+L + P C ++ + + + Q E E I Sbjct: 316 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 369 Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262 ++ + I E+ V AG R + I++ D+ PG E+T +G + Sbjct: 370 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428 Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322 G + T LA V + EL TD++ + + Sbjct: 429 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 467 Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382 S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +RGDINV + GDP T Sbjct: 468 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGT 527 Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442 AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID Sbjct: 528 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 587 Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502 EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV Sbjct: 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 647 Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546 L+ PI+SRFD+ ++ D + D +AR +V H NKEE + Sbjct: 648 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 707 Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600 Y ++ L +YI +A+ P + + + + Y ITVR Sbjct: 708 NTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 765 Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 766 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 807 >BC006165-1|AAH06165.3| 904|Homo sapiens minichromosome maintenance complex component 2 protein. Length = 904 Score = 246 bits (601), Expect = 3e-64 Identities = 189/642 (29%), Positives = 308/642 (47%), Gaps = 57/642 (8%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 258 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 259 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 315 Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202 V P+L + P C ++ + + + Q E E I Sbjct: 316 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 369 Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262 ++ + I E+ V AG R + I++ D+ PG E+T +G + Sbjct: 370 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428 Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322 G + T LA V + EL TD++ + + Sbjct: 429 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 467 Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382 S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +RGDINV + GDP T Sbjct: 468 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVRGDINVLLCGDPGT 527 Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442 AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID Sbjct: 528 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 587 Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502 EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV Sbjct: 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 647 Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546 L+ PI+SRFD+ ++ D + D +AR +V H NKEE + Sbjct: 648 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 707 Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600 Y ++ L +YI + + P + + + + Y ITVR Sbjct: 708 NTYGVEPLPQEVLKKYIIYTKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 765 Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 766 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 807 >BC017258-1|AAH17258.2| 904|Homo sapiens minichromosome maintenance complex component 2 protein. Length = 904 Score = 244 bits (597), Expect = 1e-63 Identities = 189/642 (29%), Positives = 308/642 (47%), Gaps = 57/642 (8%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 199 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 258 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 259 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 315 Query: 144 HPVHPELVQGTFYTIP-TICRNPVCANRRRFMLDADKSVFVDFQKIRIQETQAELPRGCI 202 V P+L + P C ++ + + + Q E E I Sbjct: 316 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQ---EVKPGSCPECQSAGPFEVNME---ETI 369 Query: 203 PRSLEVILRAEAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEG 262 ++ + I E+ V AG R + I++ D+ PG E+T +G + Sbjct: 370 YQNYQRIRIQESPGKVAAG-RLPRSKDAILLADLVDSCKPGDEIELTGIYHNNYDGSLNT 428 Query: 263 IKGLKALGVRELHYKTAFLACSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEM 322 G + T LA V + EL TD++ + + Sbjct: 429 ANGFPV-------FATVILANHVAKKDNKVAVGEL--------------TDEDVKMITSL 467 Query: 323 SRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLRGDINVCIVGDPST 382 S+D+ + + S+ PSI+G+ ++KRG+ L LF G K +RGDINV + GDP T Sbjct: 468 SKDQQIGEKIFASIAPSIYGHEDIKRGLALALFRGEPKNPGGKHKVRGDINVLLCGDPGT 527 Query: 383 AKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCID 442 AKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC ID Sbjct: 528 AKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLID 587 Query: 443 EFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNV 502 EFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV Sbjct: 588 EFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENV 647 Query: 503 ALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYD 546 L+ PI+SRFD+ ++ D + D +AR +V H NKEE + Sbjct: 648 DLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMP 707 Query: 547 CVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVR 600 Y ++ L +YI +A+ P + + + + Y ITVR Sbjct: 708 NTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVR 765 Query: 601 QLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 766 HIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 807 >D83987-1|BAA12177.1| 895|Homo sapiens huMCM2 protein. Length = 895 Score = 243 bits (594), Expect = 2e-63 Identities = 137/355 (38%), Positives = 212/355 (59%), Gaps = 24/355 (6%) Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369 ++TD++ + +S+D+ + + S+ PSI+G+ ++KRG+ L LFGG K +R Sbjct: 446 ELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGLALALFGGEPKNPGGKHKVR 505 Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429 GDINV + GDP TAKSQ LK + +++ RA++T+G+ +SA GLTA V R S ++ +EAG Sbjct: 506 GDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVGLTAYVQRHPVSREWTLEAG 565 Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489 AL+LAD GVC IDEFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIG Sbjct: 566 ALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIG 625 Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE- 543 GRYD + + +NV L+ PI+SRFD+ ++ D + D +AR +V H NKEE Sbjct: 626 GRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEEE 685 Query: 544 ----------SYDCVYS-----RDDLLRYIAFARS-FKPVITEEAGKLLVEYYXXXXXXX 587 + Y ++ L +YI +A+ P + + + + Y Sbjct: 686 GLANGSAAEPAMPNTYGVEPLPQEVLKKYIIYAKERVHPKLNQMDQDKVAKMYSDLRKES 745 Query: 588 XXXXXXXWRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 ITVR +ESM+R+AE A++H +V V+ A R++ +S I ++ Sbjct: 746 MATGSI--PITVRHIESMIRMAEAHARIHLRDYVIEDDVNMAIRVMLESFIDTQK 798 Score = 66.9 bits (156), Expect = 3e-10 Identities = 51/221 (23%), Positives = 102/221 (46%), Gaps = 20/221 (9%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 190 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 249 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 250 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 306 Query: 144 HPVHPELVQGTF------YTIPTICRN----------PVCANRRRFMLDADKSVFVDFQK 187 V P+L + + + C++ P C + F ++ +++++ ++Q+ Sbjct: 307 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEETIYQNYQR 366 Query: 188 IRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228 IRIQE+ ++ G +PRS + IL A+ V+S AGD + TG Sbjct: 367 IRIQESPGKVAAGRLPRSKDAILLADLVDSCNAGDEIELTG 407 >X67334-1|CAA47749.1| 892|Homo sapiens polypeptide BM28 protein. Length = 892 Score = 225 bits (550), Expect = 5e-58 Identities = 110/239 (46%), Positives = 163/239 (68%), Gaps = 5/239 (2%) Query: 310 QMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTLR 369 ++TD++ + +S+D+ + + S+ PSI+G+ ++KRG L LFGG K +R Sbjct: 444 ELTDEDVKMITSLSKDQQIGEKIFASIAPSIYGHEDIKRGPALALFGGEPKNPGGKHKVR 503 Query: 370 GDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAG 429 GDINV + GDP TAKSQ LK + +++ RA++T+G+ +SA +TA V R S ++ +EAG Sbjct: 504 GDINVLLCGDPGTAKSQFLKYIEKVSSRAIFTTGQGASAVAVTAYVQRHPVSREWTLEAG 563 Query: 430 ALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIG 489 AL+LAD GVC IDEFDKM+ D+ +IHEAMEQQ+IS++KAG+ +L AR +++AAANPIG Sbjct: 564 ALVLADRGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTSLQARCTVIAAANPIG 623 Query: 490 GRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLH-----CNKEE 543 GRYD + + +NV L+ PI+SRFD+ ++ D + D +AR +V H NKEE Sbjct: 624 GRYDPSLTFSENVDLTEPIISRFDILCVVRDTVDPVQDEMLARFVVGSHVRHHPSNKEE 682 Score = 63.7 bits (148), Expect = 2e-09 Identities = 50/221 (22%), Positives = 101/221 (45%), Gaps = 20/221 (9%) Query: 25 FQDFLEEFKEDNEIK-YEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEYYRIYPF 83 F++FL + + +++ ++ K +L V+++D+ LA + E + Sbjct: 188 FKNFLRTHVDSHGHNVFKERISDMCKENRESLVVNYEDLAAREHVLAYFLPEAPAELLQI 247 Query: 84 LNRAILNYILSLAETGMKKDLQDKECYVSFVDVPTRHKVRELTTAKIGTLIRISGQIVRT 143 + A L +L++ K D +V +P ++R L + LIR SG + Sbjct: 248 FDEAALEVVLAMYP---KYDRITNHIHVRISHLPLVEELRSLRQLHLNQLIRTSGVVTSC 304 Query: 144 HPVHPELVQGTF------YTIPTICRN----------PVCANRRRFMLDADKSVFVDFQK 187 V P+L + + + C++ P C + F ++ +++++ ++Q+ Sbjct: 305 TGVLPQLSMVKYNCNKCNFVLGPFCQSQNQEVKPGSCPECQSAGPFEVNMEETIYQNYQR 364 Query: 188 IRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTG 228 IRIQE+ ++ +PRS + IL A+ V+S AGD + TG Sbjct: 365 IRIQESPGKVAARRLPRSKDAILLADLVDSCNAGDEIELTG 405 >BC101057-1|AAI01058.1| 840|Homo sapiens MCM8 protein protein. Length = 840 Score = 225 bits (550), Expect = 5e-58 Identities = 142/395 (35%), Positives = 214/395 (54%), Gaps = 39/395 (9%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317 Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVR 272 + V+S +PG IT K++N + G R Sbjct: 318 DLVDSC----------------------VPGDTVTITGIVKVSNAEE----------GSR 345 Query: 273 ELHYKTAFLA-CSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 + K FL ++S G + D M + + K+ + E+ + NL+ Sbjct: 346 NKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKL 405 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLK 389 ++ SL P I G+ VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ Sbjct: 406 IVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQ 465 Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449 + PR VY G ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Sbjct: 466 AACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN 525 Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509 Q A+ EAMEQQ+ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++ Sbjct: 526 QHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALL 584 Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544 SRFDL FIL+D +E D+ ++ ++ + K+ + Sbjct: 585 SRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 619 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 666 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 723 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 724 ARLELREEATKEDAEDIVEIMKYSML 749 >BC101056-1|AAI01057.1| 840|Homo sapiens minichromosome maintenance complex component 8 protein. Length = 840 Score = 225 bits (550), Expect = 5e-58 Identities = 142/395 (35%), Positives = 214/395 (54%), Gaps = 39/395 (9%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317 Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVR 272 + V+S +PG IT K++N + G R Sbjct: 318 DLVDSC----------------------VPGDTVTITGIVKVSNAEE----------GSR 345 Query: 273 ELHYKTAFLA-CSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 + K FL ++S G + D M + + K+ + E+ + NL+ Sbjct: 346 NKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKL 405 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLK 389 ++ SL P I G+ VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ Sbjct: 406 IVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQ 465 Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449 + PR VY G ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Sbjct: 466 AACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN 525 Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509 Q A+ EAMEQQ+ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++ Sbjct: 526 QHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALL 584 Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544 SRFDL FIL+D +E D+ ++ ++ + K+ + Sbjct: 585 SRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 619 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 666 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 723 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 724 ARLELREEATKEDAEDIVEIMKYSML 749 >BC080656-1|AAH80656.1| 840|Homo sapiens minichromosome maintenance complex component 8 protein. Length = 840 Score = 225 bits (550), Expect = 5e-58 Identities = 142/395 (35%), Positives = 214/395 (54%), Gaps = 39/395 (9%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317 Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVR 272 + V+S +PG IT K++N + G R Sbjct: 318 DLVDSC----------------------VPGDTVTITGIVKVSNAEE----------GSR 345 Query: 273 ELHYKTAFLA-CSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 + K FL ++S G + D M + + K+ + E+ + NL+ Sbjct: 346 NKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKL 405 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLK 389 ++ SL P I G+ VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ Sbjct: 406 IVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQ 465 Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449 + PR VY G ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Sbjct: 466 AACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN 525 Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509 Q A+ EAMEQQ+ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++ Sbjct: 526 QHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALL 584 Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544 SRFDL FIL+D +E D+ ++ ++ + K+ + Sbjct: 585 SRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 619 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 666 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 723 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 724 ARLELREEATKEDAEDIVEIMKYSML 749 >BC008830-1|AAH08830.2| 735|Homo sapiens MCM8 protein protein. Length = 735 Score = 225 bits (550), Expect = 5e-58 Identities = 142/395 (35%), Positives = 214/395 (54%), Gaps = 39/395 (9%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 153 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 212 Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVR 272 + V+S +PG IT K++N + G R Sbjct: 213 DLVDSC----------------------VPGDTVTITGIVKVSNAEE----------GSR 240 Query: 273 ELHYKTAFLA-CSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 + K FL ++S G + D M + + K+ + E+ + NL+ Sbjct: 241 NKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKL 300 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLK 389 ++ SL P I G+ VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ Sbjct: 301 IVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQ 360 Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449 + PR VY G ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Sbjct: 361 AACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN 420 Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509 Q A+ EAMEQQ+ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++ Sbjct: 421 QHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALL 479 Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544 SRFDL FIL+D +E D+ ++ ++ + K+ + Sbjct: 480 SRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 514 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 561 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 618 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 619 ARLELREEATKEDAEDIVEIMKYSML 644 >AL035461-6|CAB55276.2| 840|Homo sapiens MCM8 minichromosome maintenance deficient 8 (S. cerevisiae) protein. Length = 840 Score = 225 bits (550), Expect = 5e-58 Identities = 142/395 (35%), Positives = 214/395 (54%), Gaps = 39/395 (9%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317 Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVR 272 + V+S +PG IT K++N + G R Sbjct: 318 DLVDSC----------------------VPGDTVTITGIVKVSNAEE----------GSR 345 Query: 273 ELHYKTAFLA-CSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 + K FL ++S G + D M + + K+ + E+ + NL+ Sbjct: 346 NKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKL 405 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLK 389 ++ SL P I G+ VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ Sbjct: 406 IVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQ 465 Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449 + PR VY G ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Sbjct: 466 AACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN 525 Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509 Q A+ EAMEQQ+ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++ Sbjct: 526 QHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALL 584 Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544 SRFDL FIL+D +E D+ ++ ++ + K+ + Sbjct: 585 SRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 619 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 666 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 723 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 724 ARLELREEATKEDAEDIVEIMKYSML 749 >AK027644-1|BAB55260.1| 603|Homo sapiens protein ( Homo sapiens cDNA FLJ14738 fis, clone NT2RP3002399, weakly similar to DNA REPLICATION LICENSING FACTOR MCM4. ). Length = 603 Score = 225 bits (550), Expect = 5e-58 Identities = 142/395 (35%), Positives = 214/395 (54%), Gaps = 39/395 (9%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 21 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 80 Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVR 272 + V+S +PG IT K++N + G R Sbjct: 81 DLVDSC----------------------VPGDTVTITGIVKVSNAEE----------GSR 108 Query: 273 ELHYKTAFLA-CSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 + K FL ++S G + D M + + K+ + E+ + NL+ Sbjct: 109 NKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKL 168 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLK 389 ++ SL P I G+ VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ Sbjct: 169 IVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQ 228 Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449 + PR VY G ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Sbjct: 229 AACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN 288 Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509 Q A+ EAMEQQ+ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++ Sbjct: 289 QHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALL 347 Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544 SRFDL FIL+D +E D+ ++ ++ + K+ + Sbjct: 348 SRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 382 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 429 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 486 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 487 ARLELREEATKEDAEDIVEIMKYSML 512 >AJ439063-1|CAD27750.1| 840|Homo sapiens minichromosome maintenance 8 protein. Length = 840 Score = 225 bits (550), Expect = 5e-58 Identities = 142/395 (35%), Positives = 214/395 (54%), Gaps = 39/395 (9%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317 Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGIKGLKALGVR 272 + V+S +PG IT K++N + G R Sbjct: 318 DLVDSC----------------------VPGDTVTITGIVKVSNAEE----------GSR 345 Query: 273 ELHYKTAFLA-CSVQAVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNN 331 + K FL ++S G + D M + + K+ + E+ + NL+ Sbjct: 346 NKNDKCMFLLYIEANSISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKL 405 Query: 332 LITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLK 389 ++ SL P I G+ VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ Sbjct: 406 IVNSLCPVIFGHELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQ 465 Query: 390 QVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDP 449 + PR VY G ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Sbjct: 466 AACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGN 525 Query: 450 GDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIM 509 Q A+ EAMEQQ+ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++ Sbjct: 526 QHQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALL 584 Query: 510 SRFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544 SRFDL FIL+D +E D+ ++ ++ + K+ + Sbjct: 585 SRFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 619 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 666 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 723 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 724 ARLELREEATKEDAEDIVEIMKYSML 749 >AY007130-1|AAG01994.1| 351|Homo sapiens protein ( Homo sapiens clone CDABP0042 mRNA sequence. ). Length = 351 Score = 223 bits (544), Expect = 3e-57 Identities = 117/271 (43%), Positives = 163/271 (60%), Gaps = 3/271 (1%) Query: 368 LRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIE 427 +RG+IN+C++GDP AKSQLL + + PR+ YT+G+ SS GLTAAV+RD S + +E Sbjct: 3 IRGNINICLMGDPGVAKSQLLSYIDRLAPRSQYTTGRGSSGVGLTAAVLRDSVSGELTLE 62 Query: 428 AGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANP 487 GAL+LAD GVCCIDEFDKM D+ AIHE MEQQTIS+AKAG+ TLNAR SILAAANP Sbjct: 63 GGALVLADQGVCCIDEFDKMAEADRTAIHEVMEQQTISIAKAGILTTLNARCSILAAANP 122 Query: 488 IGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKIVDLHCNKEESYDC 547 GRY+ +SL+QN+ L ++SRFDL +++ D D +A+ I +H + + Sbjct: 123 AYGRYNPRRSLEQNIQLPAALLSRFDLLWLIQDRPDRDNDLRLAQHITYVHQHSRQPPSQ 182 Query: 548 VYSRDDLL--RYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESM 605 D L RYIA R +P++ E + Y + + R L ++ Sbjct: 183 FEPLDMKLMRRYIAMCREKQPMVPESLADYITAAYVEMRREAWASKDATY-TSARTLLAI 241 Query: 606 VRLAEGVAKMHCSGHVTPAHVHEAYRLLNKS 636 +RL+ +A++ V V+EA RL+ S Sbjct: 242 LRLSTALARLRMVDVVEKEDVNEAIRLMEMS 272 >AY158211-1|AAO21222.1| 824|Homo sapiens MCM8 isoform protein. Length = 824 Score = 209 bits (511), Expect = 3e-53 Identities = 106/260 (40%), Positives = 160/260 (61%), Gaps = 3/260 (1%) Query: 287 AVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEV 346 ++S G + D M + + K+ + E+ + NL+ ++ SL P I G+ V Sbjct: 345 SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV 404 Query: 347 KRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGK 404 K G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ + PR VY G Sbjct: 405 KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN 464 Query: 405 ASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTI 464 ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Q A+ EAMEQQ+I Sbjct: 465 TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSI 523 Query: 465 SLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSE 524 SLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++SRFDL FIL+D +E Sbjct: 524 SLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNE 583 Query: 525 MVDYAIARKIVDLHCNKEES 544 D+ ++ ++ + K+ + Sbjct: 584 HHDHLLSEHVIAIRAGKQRT 603 Score = 50.8 bits (116), Expect = 2e-05 Identities = 37/111 (33%), Positives = 58/111 (52%), Gaps = 6/111 (5%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317 Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGI 263 + V+S GD TG + V A S+ S+ + +TK + +G G+ Sbjct: 318 DLVDSCVPGDTVTITGIVKVSNAEEANSISNSKGQ---KTKSSEDGCKHGM 365 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 650 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 707 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 708 ARLELREEATKEDAEDIVEIMKYSML 733 >AL035461-7|CAI23480.1| 824|Homo sapiens MCM8 minichromosome maintenance deficient 8 (S. cerevisiae) protein. Length = 824 Score = 209 bits (511), Expect = 3e-53 Identities = 106/260 (40%), Positives = 160/260 (61%), Gaps = 3/260 (1%) Query: 287 AVSRRFGTAELPTHDLTTEDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEV 346 ++S G + D M + + K+ + E+ + NL+ ++ SL P I G+ V Sbjct: 345 SISNSKGQKTKSSEDGCKHGMLMEFSLKDLYAIQEIQAEENLFKLIVNSLCPVIFGHELV 404 Query: 347 KRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGK 404 K G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ + PR VY G Sbjct: 405 KAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCGN 464 Query: 405 ASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQTI 464 ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Q A+ EAMEQQ+I Sbjct: 465 TTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQSI 523 Query: 465 SLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSE 524 SLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++SRFDL FIL+D +E Sbjct: 524 SLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLVFILLDTPNE 583 Query: 525 MVDYAIARKIVDLHCNKEES 544 D+ ++ ++ + K+ + Sbjct: 584 HHDHLLSEHVIAIRAGKQRT 603 Score = 50.8 bits (116), Expect = 2e-05 Identities = 37/111 (33%), Positives = 58/111 (52%), Gaps = 6/111 (5%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317 Query: 213 EAVESVQAGDRYDFTGTLIVVPDVGALSMPGSRAEITTRTKLANEGQMEGI 263 + V+S GD TG + V A S+ S+ + +TK + +G G+ Sbjct: 318 DLVDSCVPGDTVTITGIVKVSNAEEANSISNSKGQ---KTKSSEDGCKHGM 365 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 650 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 707 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 708 ARLELREEATKEDAEDIVEIMKYSML 733 >AK160378-1|BAD18721.1| 450|Homo sapiens FLJ00323 protein protein. Length = 450 Score = 195 bits (475), Expect = 6e-49 Identities = 97/214 (45%), Positives = 140/214 (65%), Gaps = 3/214 (1%) Query: 333 ITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLKQ 390 +TS+F S VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ Sbjct: 17 LTSVFCSFFALELVKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQA 76 Query: 391 VSEITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPG 450 + PR VY G ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Sbjct: 77 ACNVAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQ 136 Query: 451 DQVAIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMS 510 Q A+ EAMEQQ+ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++S Sbjct: 137 HQ-ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLS 195 Query: 511 RFDLFFILIDESSEMVDYAIARKIVDLHCNKEES 544 RFDL FIL+D +E D+ ++ ++ + K+ + Sbjct: 196 RFDLVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 229 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 276 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 333 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 334 ARLELREEATKEDAEDIVEIMKYSML 359 >BC101055-1|AAI01056.1| 880|Homo sapiens MCM8 protein protein. Length = 880 Score = 190 bits (462), Expect = 2e-47 Identities = 93/201 (46%), Positives = 134/201 (66%), Gaps = 3/201 (1%) Query: 346 VKRGVLLMLFGGVAKTTIEGTTL--RGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSG 403 VK G+ L LFGG K + + RGD ++ +VGDP KSQ+L+ + PR VY G Sbjct: 460 VKAGLALALFGGSQKYADDKNRIPIRGDPHILVVGDPGLGKSQMLQAACNVAPRGVYVCG 519 Query: 404 KASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAMEQQT 463 ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Q A+ EAMEQQ+ Sbjct: 520 NTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ-ALLEAMEQQS 578 Query: 464 ISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESS 523 ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++SRFDL FIL+D + Sbjct: 579 ISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFDLAFILLDTPN 638 Query: 524 EMVDYAIARKIVDLHCNKEES 544 E D+ ++ ++ + K+ + Sbjct: 639 EHHDHLLSEHVIAIRAGKQRT 659 Score = 46.8 bits (106), Expect = 3e-04 Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 3/80 (3%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317 Query: 213 EAVESVQAGDRYDFTGTLIV 232 + V+S GD TG + V Sbjct: 318 DLVDSCVPGDTVTITGIVKV 337 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 706 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 763 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 764 ARLELREEATKEDAEDIVEIMKYSML 789 >BC000300-1|AAH00300.2| 362|Homo sapiens MCM2 protein protein. Length = 362 Score = 167 bits (406), Expect = 1e-40 Identities = 102/267 (38%), Positives = 155/267 (58%), Gaps = 24/267 (8%) Query: 398 AVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHE 457 A++T+G+ +SA GLTA V R S ++ +EAGAL+LAD GVC IDEFDKM+ D+ +IHE Sbjct: 1 AIFTTGQGASAVGLTAYVQRHPVSREWTLEAGALVLADRGVCLIDEFDKMNDQDRTSIHE 60 Query: 458 AMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFI 517 AMEQQ+IS++KAG+ +L AR +++AAANPIGGRYD + + +NV L+ PI+SRFD+ + Sbjct: 61 AMEQQSISISKAGIVTSLQARCTVIAAANPIGGRYDPSLTFSENVDLTEPIISRFDILCV 120 Query: 518 LIDESSEMVDYAIARKIVDLH-----CNKEE-----------SYDCVYS-----RDDLLR 556 + D + D +AR +V H NKEE + Y ++ L + Sbjct: 121 VRDTVDPVQDEMLARFVVGSHVRHHPSNKEEEGLANGSAAEPAMPNTYGVEPLPQEVLKK 180 Query: 557 YIAFARS-FKPVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGVAKM 615 YI +A+ P + + + + Y ITVR +ESM+R+AE A++ Sbjct: 181 YIIYAKERVHPKLNQMDQDKVAKMYSDLRKESMATGSI--PITVRHIESMIRMAEAHARI 238 Query: 616 HCSGHVTPAHVHEAYRLLNKSIIRVEQ 642 H +V V+ A R++ +S I ++ Sbjct: 239 HLRDYVIEDDVNMAIRVMLESFIDTQK 265 >BC101054-1|AAI01055.1| 793|Homo sapiens MCM8 protein protein. Length = 793 Score = 156 bits (378), Expect = 3e-37 Identities = 73/151 (48%), Positives = 106/151 (70%), Gaps = 1/151 (0%) Query: 394 ITPRAVYTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQV 453 + PR VY G ++ +GLT + +D S DF +EAGAL+L D G+C IDEFDKM Q Sbjct: 423 VAPRGVYVCGNTTTTSGLTVTLSKDSSSGDFALEAGALVLGDQGICGIDEFDKMGNQHQ- 481 Query: 454 AIHEAMEQQTISLAKAGVRATLNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFD 513 A+ EAMEQQ+ISLAKAGV +L ARTSI+AAANP+GG Y++AK++ +N+ + ++SRFD Sbjct: 482 ALLEAMEQQSISLAKAGVVCSLPARTSIIAAANPVGGHYNKAKTVSENLKMGSALLSRFD 541 Query: 514 LFFILIDESSEMVDYAIARKIVDLHCNKEES 544 L FIL+D +E D+ ++ ++ + K+ + Sbjct: 542 LVFILLDTPNEHHDHLLSEHVIAIRAGKQRT 572 Score = 46.8 bits (106), Expect = 3e-04 Identities = 30/80 (37%), Positives = 44/80 (55%), Gaps = 3/80 (3%) Query: 156 YTIPTICRNPVCANRRRFMLDADK-SVFVDFQKIRIQETQAELPR--GCIPRSLEVILRA 212 Y++PT C PVC R L + +V +D+Q I+IQE ++ R G IPR++E L Sbjct: 258 YSLPTKCPVPVCRGRSFTALRSSPLTVTMDWQSIKIQELMSDDQREAGRIPRTIECELVH 317 Query: 213 EAVESVQAGDRYDFTGTLIV 232 + V+S GD TG + V Sbjct: 318 DLVDSCVPGDTVTITGIVKV 337 Score = 39.1 bits (87), Expect = 0.061 Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 3/86 (3%) Query: 554 LLRYIAFARSFK-PVITEEAGKLLVEYYXXXXXXXXXXXXXXWRITVRQLESMVRLAEGV 612 L +YI +AR + P ++ EA ++L ++Y IT RQLES++RL E Sbjct: 619 LRKYIGYARQYVYPRLSTEAARVLQDFYLELRKQSQRLNSSP--ITTRQLESLIRLTEAR 676 Query: 613 AKMHCSGHVTPAHVHEAYRLLNKSII 638 A++ T + ++ S++ Sbjct: 677 ARLELREEATKEDAEDIVEIMKYSML 702 >U67284-1|AAB48165.1| 181|Homo sapiens homolog of S. pombe mis5 protein. Length = 181 Score = 143 bits (346), Expect = 3e-33 Identities = 81/192 (42%), Positives = 125/192 (65%), Gaps = 26/192 (13%) Query: 621 VTPAHVHEAYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEP--NGTAETPS----- 673 V P HV EA+RLLNKSIIRVE PD++LD++E E M+VD+ NG A++P+ Sbjct: 1 VQPKHVKEAFRLLNKSIIRVETPDVNLDQEE---EIQMEVDEGAGGINGHADSPAPVNGI 57 Query: 674 -------NGDSAPKKKLALSFEEYKSLSNMLVVYMRKXXXXXXXXXXXSSGMHKSAVVSW 726 N +SAPK L L F EY +SN++V+++RK S + +S +V+W Sbjct: 58 NGYNEDINQESAPKASLRLGFSEYCRISNLIVLHLRKVEEED------ESALKRSELVNW 111 Query: 727 YLEQLVAQGQIESEDELLERKTLVEKVIDRLMYHDQVIIPLSTTGLRGTQKSSEQDIEDD 786 YL+++ + +I+SE+EL+ +K ++EKVI RL ++D V+I L+ GL+G+ + SE E+D Sbjct: 112 YLKEI--ESEIDSEEELINKKRIIEKVIHRLTHYDHVLIELTQAGLKGSTEGSE-SYEED 168 Query: 787 PLLVVHPNYVVD 798 P LVV+PNY+++ Sbjct: 169 PYLVVNPNYLLE 180 >AL132874-5|CAI42607.1| 451|Homo sapiens protein ( an). ).). Length = 451 Score = 84.6 bits (200), Expect = 1e-15 Identities = 50/148 (33%), Positives = 82/148 (55%), Gaps = 5/148 (3%) Query: 475 LNARTSILAAANPIGGRYDRAKSLQQNVALSPPIMSRFDLFFILIDESSEMVDYAIARKI 534 LN RT+ILAA NP G+YD +S+ N+AL P++SRFDL +L+D +E D I+ I Sbjct: 290 LNTRTTILAATNP-KGQYDPQESVSVNIALGSPLLSRFDLILVLLDTKNEDWDRIISSFI 348 Query: 535 VDLHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYXXXXXXXXXXXXXX 594 ++ +S + ++S + + Y R+ +P +++ ++L+ YY Sbjct: 349 LENKGYPSKS-EKLWSMEKMKTYFCLIRNLQPTLSDVGNQVLLRYYQMQRQSDCRNAA-- 405 Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVT 622 R T+R LES++RLAE A++ VT Sbjct: 406 -RTTIRLLESLIRLAEAHARLMFRDTVT 432 Score = 78.2 bits (184), Expect = 1e-13 Identities = 42/107 (39%), Positives = 66/107 (61%), Gaps = 3/107 (2%) Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364 E+++K+ D W+ Y S N ++ SL P + G VK V ++L GG+ +T Sbjct: 172 EEVQKEFEDF-WE--YYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAT 228 Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGL 411 GT +RG+ ++ +VGDP T KSQ LK ++ITPR+V T+G S++AG+ Sbjct: 229 GTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGI 275 Score = 41.9 bits (94), Expect = 0.009 Identities = 20/48 (41%), Positives = 31/48 (64%) Query: 184 DFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLI 231 D+Q+I+IQE L G IPRS++VIL + V+S ++GD G ++ Sbjct: 88 DYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVM 135 >BC031658-1|AAH31658.1| 391|Homo sapiens minichromosome maintenance complex component 9 protein. Length = 391 Score = 78.2 bits (184), Expect = 1e-13 Identities = 42/107 (39%), Positives = 66/107 (61%), Gaps = 3/107 (2%) Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364 E+++K+ D W+ Y S N ++ SL P + G VK V ++L GG+ +T Sbjct: 282 EEVQKEFEDF-WE--YYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAT 338 Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGL 411 GT +RG+ ++ +VGDP T KSQ LK ++ITPR+V T+G S++AG+ Sbjct: 339 GTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGI 385 Score = 41.9 bits (94), Expect = 0.009 Identities = 20/48 (41%), Positives = 31/48 (64%) Query: 184 DFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAGDRYDFTGTLI 231 D+Q+I+IQE L G IPRS++VIL + V+S ++GD G ++ Sbjct: 198 DYQEIKIQEQVQRLSVGSIPRSMKVILEDDLVDSCKSGDDLTIYGIVM 245 >AL132874-4|CAI42606.1| 156|Homo sapiens protein ( Human DNA sequence from clone RP3-329L24 on chromosome 6q22.1-22.33.om chromosome 14 of Homo sapiens (Human). ). Length = 156 Score = 78.2 bits (184), Expect = 1e-13 Identities = 42/107 (39%), Positives = 66/107 (61%), Gaps = 3/107 (2%) Query: 305 EDMRKQMTDKEWDKVYEMSRDRNLYNNLITSLFPSIHGNNEVKRGVLLMLFGGVAKTTIE 364 E+++K+ D W+ Y S N ++ SL P + G VK V ++L GG+ +T Sbjct: 47 EEVQKEFEDF-WE--YYKSDPFAGRNVILASLCPQVFGMYLVKLAVAMVLAGGIQRTDAT 103 Query: 365 GTTLRGDINVCIVGDPSTAKSQLLKQVSEITPRAVYTSGKASSAAGL 411 GT +RG+ ++ +VGDP T KSQ LK ++ITPR+V T+G S++AG+ Sbjct: 104 GTRVRGESHLLLVGDPGTGKSQFLKYAAKITPRSVLTTGIGSTSAGI 150 >BC009398-1|AAH09398.1| 389|Homo sapiens MCM7 protein protein. Length = 389 Score = 52.8 bits (121), Expect = 5e-06 Identities = 37/136 (27%), Positives = 60/136 (44%), Gaps = 20/136 (14%) Query: 122 VRELTTAKIGTLIRISGQIVRTHPVHPELVQGTF------------YTIPT-----ICRN 164 +RE+ +G L+ + G + R V P++V T+ PT +C + Sbjct: 149 IREVRADSVGKLVTVRGIVTRVSEVKPKMVVATYTCDQCGAETYQPIQSPTFMPLIMCPS 208 Query: 165 PVCANRR---RFMLDADKSVFVDFQKIRIQETQAELPRGCIPRSLEVILRAEAVESVQAG 221 C R R L S F+ FQ++++QE ++P G IPRS+ V++ E Q G Sbjct: 209 QECQTNRSGGRLYLQTRGSRFIKFQEMKMQEHSDQVPVGNIPRSITVLVEGENTRIAQPG 268 Query: 222 DRYDFTGTLIVVPDVG 237 D TG + + G Sbjct: 269 DHVSVTGIFLPILRTG 284 >AL034343-2|CAD92644.1| 328|Homo sapiens MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) protein. Length = 328 Score = 45.6 bits (103), Expect = 7e-04 Identities = 36/134 (26%), Positives = 57/134 (42%), Gaps = 7/134 (5%) Query: 537 LHCNKEESYDCVYSRDDLLRYIAFARSFKPVITEEAGKLLVEYYX--XXXXXXXXXXXXX 594 LH K++ V S + +YI A+ KPV+T+E+ + E Y Sbjct: 47 LHGTKKKKEKMV-SAAFMKKYIHVAKIIKPVLTQESATYIAEEYSRLRSQDSMSSDTART 105 Query: 595 WRITVRQLESMVRLAEGVAKMHCSGHVTPAHVHEAYRLLN----KSIIRVEQPDIHLDED 650 +T R LE+++RLA AK S V EA L+ K ++ E+ ED Sbjct: 106 SPVTARTLETLIRLATAHAKARMSKTVDLQDAEEAVELVQYAYFKKVLEKEKKRKKRSED 165 Query: 651 EPQCEPSMDVDQDE 664 E + E + Q++ Sbjct: 166 ESETEDEEEKSQED 179 >U09584-1|AAA92281.1| 351|Homo sapiens PL6 protein protein. Length = 351 Score = 33.5 bits (73), Expect = 3.0 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Query: 629 AYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTAETPSNGDSAPKKKLALSFE 688 A + LN+ + RVE I D+ + E VD P+ A TP +AP+ L ++FE Sbjct: 287 ALKALNERLKRVEDQSIWPSMDDDEEESGAKVDSPLPSDKAPTPPGKGAAPESSL-ITFE 345 >CR457020-1|CAG33301.1| 351|Homo sapiens PL6 protein. Length = 351 Score = 33.5 bits (73), Expect = 3.0 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Query: 629 AYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTAETPSNGDSAPKKKLALSFE 688 A + LN+ + RVE I D+ + E VD P+ A TP +AP+ L ++FE Sbjct: 287 ALKALNERLKRVEDQSIWPSMDDDEEESGAKVDSPLPSDKAPTPPGKGAAPESSL-ITFE 345 >BC017367-1|AAH17367.1| 351|Homo sapiens transmembrane protein 115 protein. Length = 351 Score = 33.5 bits (73), Expect = 3.0 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Query: 629 AYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTAETPSNGDSAPKKKLALSFE 688 A + LN+ + RVE I D+ + E VD P+ A TP +AP+ L ++FE Sbjct: 287 ALKALNERLKRVEDQSIWPSMDDDEEESGAKVDSPLPSDKAPTPPGKGAAPESSL-ITFE 345 >BC011948-1|AAH11948.1| 351|Homo sapiens transmembrane protein 115 protein. Length = 351 Score = 33.5 bits (73), Expect = 3.0 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Query: 629 AYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTAETPSNGDSAPKKKLALSFE 688 A + LN+ + RVE I D+ + E VD P+ A TP +AP+ L ++FE Sbjct: 287 ALKALNERLKRVEDQSIWPSMDDDEEESGAKVDSPLPSDKAPTPPGKGAAPESSL-ITFE 345 >AC002481-1|AAB67308.1| 247|Homo sapiens PL6 protein, unknown function but deleted in small cell lung cancer protein. Length = 247 Score = 33.5 bits (73), Expect = 3.0 Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%) Query: 629 AYRLLNKSIIRVEQPDIHLDEDEPQCEPSMDVDQDEPNGTAETPSNGDSAPKKKLALSFE 688 A + LN+ + RVE I D+ + E VD P+ A TP +AP+ L ++FE Sbjct: 183 ALKALNERLKRVEDQSIWPSMDDDEEESGAKVDSPLPSDKAPTPPGKGAAPESSL-ITFE 241 >CR457191-1|CAG33472.1| 303|Homo sapiens MRPL1 protein. Length = 303 Score = 32.3 bits (70), Expect = 6.9 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 29 LEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEY-YRIYPFLNRA 87 LE FK +EIK ++ + L+ +++TL++S D + Q + + + PF+ RA Sbjct: 212 LELFKNGHEIKVDEERENFLQTKIATLDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRA 271 Query: 88 IL 89 L Sbjct: 272 FL 273 >BC104483-1|AAI04484.1| 495|Homo sapiens SUV420H1 protein protein. Length = 495 Score = 32.3 bits (70), Expect = 6.9 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 400 YTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAM 459 + SG SS+ L + RDEE+ E L +NGVCC D ++ +V + Sbjct: 376 FNSGSGSSSTKLKIQLKRDEENRGSYTEG----LHENGVCCSDPLSLLESRMEVDDYSQY 431 Query: 460 EQQT 463 E+++ Sbjct: 432 EEES 435 >BC103498-1|AAI03499.1| 885|Homo sapiens suppressor of variegation 4-20 homolog 1, isoform 1 protein. Length = 885 Score = 32.3 bits (70), Expect = 6.9 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 400 YTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAM 459 + SG SS+ L + RDEE+ E L +NGVCC D ++ +V + Sbjct: 766 FNSGSGSSSTKLKIQLKRDEENRGSYTEG----LHENGVCCSDPLSLLESRMEVDDYSQY 821 Query: 460 EQQT 463 E+++ Sbjct: 822 EEES 825 >BC099714-1|AAH99714.1| 885|Homo sapiens suppressor of variegation 4-20 homolog 1 (Drosophila) protein. Length = 885 Score = 32.3 bits (70), Expect = 6.9 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 400 YTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAM 459 + SG SS+ L + RDEE+ E L +NGVCC D ++ +V + Sbjct: 766 FNSGSGSSSTKLKIQLKRDEENRGSYTEG----LHENGVCCSDPLSLLESRMEVDDYSQY 821 Query: 460 EQQT 463 E+++ Sbjct: 822 EEES 825 >BC098121-1|AAH98121.1| 471|Homo sapiens SUV420H1 protein protein. Length = 471 Score = 32.3 bits (70), Expect = 6.9 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 400 YTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAM 459 + SG SS+ L + RDEE+ E L +NGVCC D ++ +V + Sbjct: 352 FNSGSGSSSTKLKIQLKRDEENRGSYTEG----LHENGVCCSDPLSLLESRMEVDDYSQY 407 Query: 460 EQQT 463 E+++ Sbjct: 408 EEES 411 >BC032595-1|AAH32595.1| 303|Homo sapiens mitochondrial ribosomal protein L1 protein. Length = 303 Score = 32.3 bits (70), Expect = 6.9 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 29 LEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEY-YRIYPFLNRA 87 LE FK +EIK ++ + L+ +++TL++S D + Q + + + PF+ RA Sbjct: 212 LELFKNGHEIKVDEERENFLQTKIATLDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRA 271 Query: 88 IL 89 L Sbjct: 272 FL 273 >BC017765-1|AAH17765.1| 302|Homo sapiens Unknown (protein for IMAGE:4284885) protein. Length = 302 Score = 32.3 bits (70), Expect = 6.9 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 29 LEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEY-YRIYPFLNRA 87 LE FK +EIK ++ + L+ +++TL++S D + Q + + + PF+ RA Sbjct: 212 LELFKNGHEIKVDEERENFLQTKIATLDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRA 271 Query: 88 IL 89 L Sbjct: 272 FL 273 >BC015109-1|AAH15109.1| 303|Homo sapiens mitochondrial ribosomal protein L1 protein. Length = 303 Score = 32.3 bits (70), Expect = 6.9 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 29 LEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEY-YRIYPFLNRA 87 LE FK +EIK ++ + L+ +++TL++S D + Q + + + PF+ RA Sbjct: 212 LELFKNGHEIKVDEERENFLQTKIATLDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRA 271 Query: 88 IL 89 L Sbjct: 272 FL 273 >BC014356-1|AAH14356.1| 303|Homo sapiens mitochondrial ribosomal protein L1 protein. Length = 303 Score = 32.3 bits (70), Expect = 6.9 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 29 LEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEY-YRIYPFLNRA 87 LE FK +EIK ++ + L+ +++TL++S D + Q + + + PF+ RA Sbjct: 212 LELFKNGHEIKVDEERENFLQTKIATLDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRA 271 Query: 88 IL 89 L Sbjct: 272 FL 273 >BC012933-1|AAH12933.1| 414|Homo sapiens SUV420H1 protein protein. Length = 414 Score = 32.3 bits (70), Expect = 6.9 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 400 YTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAM 459 + SG SS+ L + RDEE+ E L +NGVCC D ++ +V + Sbjct: 295 FNSGSGSSSTKLKIQLKRDEENRGSYTEG----LHENGVCCSDPLSLLESRMEVDDYSQY 350 Query: 460 EQQT 463 E+++ Sbjct: 351 EEES 354 >AK000046-1|BAA90905.1| 414|Homo sapiens protein ( Homo sapiens cDNA FLJ20039 fis, clone COL00364. ). Length = 414 Score = 32.3 bits (70), Expect = 6.9 Identities = 19/64 (29%), Positives = 31/64 (48%), Gaps = 4/64 (6%) Query: 400 YTSGKASSAAGLTAAVVRDEESFDFVIEAGALMLADNGVCCIDEFDKMDPGDQVAIHEAM 459 + SG SS+ L + RDEE+ E L +NGVCC D ++ +V + Sbjct: 295 FNSGSGSSSTKLKIQLKRDEENRGSYTEG----LHENGVCCSDPLSLLESRMEVDDYSQY 350 Query: 460 EQQT 463 E+++ Sbjct: 351 EEES 354 >AC011999-1|AAY15028.1| 35|Homo sapiens unknown protein. Length = 35 Score = 32.3 bits (70), Expect = 6.9 Identities = 13/19 (68%), Positives = 16/19 (84%) Query: 12 QVKDEVGIRCQKLFQDFLE 30 +V+DEV +CQKLF DFLE Sbjct: 17 EVRDEVAEKCQKLFLDFLE 35 >AB049474-1|BAB40180.1| 303|Homo sapiens mitochondrial ribosomal protein L1 (L1mt) protein. Length = 303 Score = 32.3 bits (70), Expect = 6.9 Identities = 18/62 (29%), Positives = 33/62 (53%), Gaps = 1/62 (1%) Query: 29 LEEFKEDNEIKYEKHAKELLKPELSTLEVSFDDVEKYNQNLATTIIEEY-YRIYPFLNRA 87 LE FK +EIK ++ + L+ +++TL++S D + Q + + + PF+ RA Sbjct: 212 LELFKNGHEIKVDEERENFLQTKIATLDMSSDQIAANLQAVINEVCRHRPLNLGPFVVRA 271 Query: 88 IL 89 L Sbjct: 272 FL 273 Database: human Posted date: Oct 5, 2007 11:13 AM Number of letters in database: 73,234,838 Number of sequences in database: 224,733 Lambda K H 0.318 0.134 0.380 Gapped Lambda K H 0.279 0.0580 0.190 Matrix: BLOSUM62 Gap Penalties: Existence: 9, Extension: 2 Number of Hits to DB: 100,796,120 Number of Sequences: 224733 Number of extensions: 3911365 Number of successful extensions: 11174 Number of sequences better than 10.0: 80 Number of HSP's better than 10.0 without gapping: 67 Number of HSP's successfully gapped in prelim test: 13 Number of HSP's that attempted gapping in prelim test: 10876 Number of HSP's gapped (non-prelim): 199 length of query: 799 length of database: 73,234,838 effective HSP length: 96 effective length of query: 703 effective length of database: 51,660,470 effective search space: 36317310410 effective search space used: 36317310410 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 37 (14.9 bits) X3: 62 (25.0 bits) S1: 41 (21.7 bits) S2: 69 (31.9 bits)
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