Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= BGIBMGA000827-TA|BGIBMGA000827-PA|IPR007835|MOFRL
(421 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D55F73 Cluster: PREDICTED: similar to RIKEN cDNA... 355 2e-96
UniRef50_A7SEK0 Cluster: Predicted protein; n=4; Eumetazoa|Rep: ... 316 5e-85
UniRef50_Q17JZ2 Cluster: Glycerate kinase; n=2; Culicidae|Rep: G... 309 1e-82
UniRef50_Q8IVS8 Cluster: Glycerate kinase; n=31; Euteleostomi|Re... 305 1e-81
UniRef50_Q9VQC4 Cluster: Glycerate kinase; n=2; Sophophora|Rep: ... 291 3e-77
UniRef50_UPI00015B42A9 Cluster: PREDICTED: hypothetical protein;... 264 4e-69
UniRef50_Q4RX75 Cluster: Chromosome 11 SCAF14979, whole genome s... 259 1e-67
UniRef50_A1RWN7 Cluster: Hydroxypyruvate reductase; n=1; Thermof... 216 1e-54
UniRef50_Q09235 Cluster: Uncharacterized protein C13B9.2; n=2; C... 212 1e-53
UniRef50_Q648E2 Cluster: Putative glycerate kinase; n=1; uncultu... 210 5e-53
UniRef50_Q1PYP3 Cluster: Putative uncharacterized protein; n=1; ... 192 2e-47
UniRef50_A5UUT0 Cluster: Hydroxypyruvate reductase; n=4; Chlorof... 191 3e-47
UniRef50_A3DMH9 Cluster: MOFRL domain protein; n=1; Staphylother... 182 1e-44
UniRef50_Q2LX73 Cluster: Glycerate dehydrogenase / hydroxypyruva... 177 4e-43
UniRef50_Q04S94 Cluster: Glycerate kinase; n=3; Leptospira|Rep: ... 172 2e-41
UniRef50_UPI0000DB7A11 Cluster: PREDICTED: similar to CG9886-lik... 163 6e-39
UniRef50_A3H6I3 Cluster: Hydroxypyruvate reductase; n=1; Caldivi... 161 2e-38
UniRef50_Q7UK87 Cluster: Putative uncharacterized protein; n=1; ... 150 6e-35
UniRef50_Q0G2B9 Cluster: MOFRL domain protein; n=1; Fulvimarina ... 144 5e-33
UniRef50_A3ZMR6 Cluster: Putative uncharacterized protein; n=2; ... 142 1e-32
UniRef50_UPI0000DB723F Cluster: PREDICTED: similar to CG9886-lik... 141 4e-32
UniRef50_A1IFB6 Cluster: Hydroxypyruvate reductase; n=2; Bacteri... 138 3e-31
UniRef50_Q0W1M0 Cluster: Putative hydroxypyruvate reductase; n=1... 138 3e-31
UniRef50_Q5V6W3 Cluster: Putative hydroxypyruvate reductase; n=1... 134 3e-30
UniRef50_Q8G2G7 Cluster: Hydroxypyruvate reductase, putative; n=... 132 1e-29
UniRef50_A7D4B1 Cluster: Hydroxypyruvate reductase; n=1; Halorub... 132 1e-29
UniRef50_Q12DK9 Cluster: Hydroxypyruvate reductase; n=6; Proteob... 132 2e-29
UniRef50_A7CF57 Cluster: Hydroxypyruvate reductase; n=10; Proteo... 132 2e-29
UniRef50_Q1AS62 Cluster: Hydroxypyruvate reductase; n=1; Rubroba... 131 3e-29
UniRef50_A0LQ82 Cluster: MOFRL domain protein; n=1; Syntrophobac... 131 4e-29
UniRef50_Q9X1S1 Cluster: Glycerate kinase, putative; n=7; Bacter... 129 2e-28
UniRef50_A4WI53 Cluster: Hydroxypyruvate reductase; n=4; Thermop... 128 4e-28
UniRef50_Q5LT50 Cluster: MOFRL domain protein; n=6; Rhodobactera... 127 5e-28
UniRef50_Q0LLX8 Cluster: Hydroxypyruvate reductase; n=1; Herpeto... 127 6e-28
UniRef50_A4T037 Cluster: Hydroxypyruvate reductase; n=2; Burkhol... 127 6e-28
UniRef50_A7DNA1 Cluster: Hydroxypyruvate reductase; n=1; Candida... 126 1e-27
UniRef50_A3V819 Cluster: MOFRL domain protein; n=2; Rhodobactera... 122 2e-26
UniRef50_Q30XP9 Cluster: Hydroxypyruvate reductase; n=3; Desulfo... 121 3e-26
UniRef50_Q44472 Cluster: Putative hydroxypyruvate reductase; n=7... 119 1e-25
UniRef50_Q2Y6U9 Cluster: Hydroxypyruvate reductase precursor; n=... 118 3e-25
UniRef50_Q18JL1 Cluster: Probable hydroxypyruvate reductase; pro... 118 3e-25
UniRef50_Q1ISV4 Cluster: Hydroxypyruvate reductase; n=1; Acidoba... 114 5e-24
UniRef50_A6LJ61 Cluster: Hydroxypyruvate reductase; n=1; Thermos... 114 5e-24
UniRef50_Q9YDB7 Cluster: Glycerate kinase; n=1; Aeropyrum pernix... 113 6e-24
UniRef50_A6GR07 Cluster: Putative hydroxypyruvate reductase oxid... 113 8e-24
UniRef50_Q97AL3 Cluster: Glycerate kinase; n=5; Thermoplasmatale... 107 5e-22
UniRef50_Q1J385 Cluster: Hydroxypyruvate reductase; n=4; Deinoco... 106 9e-22
UniRef50_Q0FEP1 Cluster: MOFRL domain protein; n=1; alpha proteo... 106 9e-22
UniRef50_A6X7S4 Cluster: Hydroxypyruvate reductase; n=1; Ochroba... 103 1e-20
UniRef50_A0RVR5 Cluster: Hydroxypyruvate reductase; n=1; Cenarch... 102 2e-20
UniRef50_Q6W213 Cluster: Glycerate dehydrogenase / Hydroxypyruva... 101 5e-20
UniRef50_A7H7H1 Cluster: MOFRL domain protein; n=2; Anaeromyxoba... 97 6e-19
UniRef50_Q2S2B0 Cluster: Hydroxypyruvate reductase; n=1; Salinib... 97 8e-19
UniRef50_Q15Z21 Cluster: Hydroxypyruvate reductase; n=2; Alterom... 96 2e-18
UniRef50_Q3IT62 Cluster: Probable hydroxypyruvate reductase; pro... 95 2e-18
UniRef50_Q89CG7 Cluster: Hydroxypyruvate reductase; n=14; Alphap... 94 7e-18
UniRef50_A6GGC1 Cluster: Probable hydroxypyruvate reductase ; pr... 77 7e-13
UniRef50_Q4JCE1 Cluster: MOFRL family protein; n=4; Sulfolobacea... 76 2e-12
UniRef50_Q5JEQ8 Cluster: Glycerate kinase-related protein, conta... 73 1e-11
UniRef50_A3ESH2 Cluster: Putative glycerate kinase; n=1; Leptosp... 73 1e-11
UniRef50_A3JCN1 Cluster: Hydroxypyruvate reductase; n=1; Marinob... 70 1e-10
UniRef50_Q703V9 Cluster: Glycerate kinase; n=1; Thermoproteus te... 70 1e-10
UniRef50_A7BX18 Cluster: Hydroxypyruvate reductase; n=1; Beggiat... 69 3e-10
UniRef50_A6VRW1 Cluster: MOFRL domain protein; n=2; Proteobacter... 67 9e-10
UniRef50_A4BRW4 Cluster: MOFRL family protein; n=1; Nitrococcus ... 58 3e-07
UniRef50_UPI00015B8F69 Cluster: UPI00015B8F69 related cluster; n... 57 8e-07
UniRef50_Q5LP57 Cluster: MOFRL family protein; n=1; Silicibacter... 57 8e-07
UniRef50_Q0IHN8 Cluster: Putative uncharacterized protein MGC147... 52 4e-05
UniRef50_A5D6S7 Cluster: LOC553494 protein; n=4; Danio rerio|Rep... 40 0.093
UniRef50_Q9Y1J4 Cluster: Retinoid X receptor RXR-2; n=10; Bilate... 40 0.12
UniRef50_Q6LF21 Cluster: Putative DNA polymerase i; n=1; Plasmod... 40 0.16
UniRef50_Q8AAI2 Cluster: Tyrosine-protein kinase ptk; n=9; Bacte... 38 0.37
UniRef50_A4XK74 Cluster: Methyl-accepting chemotaxis sensory tra... 38 0.37
UniRef50_A5ULC4 Cluster: Archaeosine tRNA-ribosyltransferase; n=... 38 0.37
UniRef50_A7A6B7 Cluster: Putative uncharacterized protein; n=1; ... 38 0.50
UniRef50_Q4YRL8 Cluster: Putative uncharacterized protein; n=2; ... 38 0.66
UniRef50_Q897I5 Cluster: Putative surface/cell-adhesion protein,... 37 0.87
UniRef50_Q71TP0 Cluster: Sit; n=3; Enterobacteria phage P1|Rep: ... 37 0.87
UniRef50_A0V0Z2 Cluster: Putative uncharacterized protein; n=1; ... 37 1.1
UniRef50_Q8I5X6 Cluster: Putative uncharacterized protein; n=1; ... 37 1.1
UniRef50_Q6BFI1 Cluster: Putative uncharacterized protein; n=1; ... 37 1.1
UniRef50_A0CQ45 Cluster: Chromosome undetermined scaffold_24, wh... 37 1.1
UniRef50_Q4FST6 Cluster: ABC sulfate/thiosulfate transporter, pe... 36 1.5
UniRef50_A0J3G5 Cluster: Putative uncharacterized protein; n=1; ... 36 1.5
UniRef50_Q4CSS9 Cluster: Protein kinase, putative; n=2; Trypanos... 36 1.5
UniRef50_Q1QEB0 Cluster: Putative uncharacterized protein; n=1; ... 36 2.0
UniRef50_A6LUV0 Cluster: 2-dehydropantoate 2-reductase; n=1; Clo... 36 2.0
UniRef50_A5TSU9 Cluster: Possible TPS family two-partner secreti... 36 2.0
UniRef50_Q10411 Cluster: Sporulation-specific protein 15; n=1; S... 36 2.0
UniRef50_Q6F1S3 Cluster: Putative NAD kinase; n=1; Mesoplasma fl... 36 2.6
UniRef50_A0QNZ8 Cluster: Secreted protein; n=6; Mycobacterium|Re... 36 2.6
UniRef50_Q8IAM6 Cluster: Putative uncharacterized protein MAL8P1... 36 2.6
UniRef50_Q7R8P5 Cluster: OGG1 protein type 2e-related; n=2; Plas... 36 2.6
UniRef50_Q4UGA6 Cluster: Putative uncharacterized protein; n=2; ... 36 2.6
UniRef50_Q4J7L2 Cluster: Conserved protein; n=2; Sulfolobus|Rep:... 36 2.6
UniRef50_Q60390 Cluster: Methyl-coenzyme M reductase II subunit ... 36 2.6
UniRef50_A5N599 Cluster: IlvE1; n=8; Bacteria|Rep: IlvE1 - Clost... 35 3.5
UniRef50_Q86I70 Cluster: Putative uncharacterized protein; n=2; ... 35 3.5
UniRef50_Q54DE7 Cluster: Patatin domain-containing protein; n=1;... 35 3.5
UniRef50_Q2CF81 Cluster: Putative uncharacterized protein; n=1; ... 35 4.6
UniRef50_Q2B211 Cluster: Serine protease Do; n=1; Bacillus sp. N... 35 4.6
UniRef50_Q9N9H5 Cluster: Guanylyl cyclase; n=3; Plasmodium falci... 35 4.6
UniRef50_Q4Z3Z7 Cluster: MRNA (N6-adenosine)-methyltransferase, ... 35 4.6
UniRef50_Q234L4 Cluster: Putative uncharacterized protein; n=1; ... 35 4.6
UniRef50_UPI00006CCFDA Cluster: Protein kinase domain containing... 34 6.1
UniRef50_UPI000051A58B Cluster: PREDICTED: similar to solute car... 34 6.1
UniRef50_UPI0000397283 Cluster: COG5295: Autotransporter adhesin... 34 6.1
UniRef50_UPI0000F32DF2 Cluster: UPI0000F32DF2 related cluster; n... 34 6.1
UniRef50_A7GY70 Cluster: Dead/deah box helicase:hd domain; n=2; ... 34 6.1
UniRef50_A0NTH0 Cluster: Transcriptional regulator; n=1; Stappia... 34 6.1
UniRef50_A7NV36 Cluster: Chromosome chr18 scaffold_1, whole geno... 34 6.1
UniRef50_Q8SCK9 Cluster: PHIKZ303; n=1; Pseudomonas phage phiKZ|... 34 6.1
UniRef50_Q4UAJ2 Cluster: Adapter protein, putative; n=1; Theiler... 34 6.1
UniRef50_A0CZ47 Cluster: Chromosome undetermined scaffold_312, w... 34 6.1
UniRef50_A0C1B6 Cluster: Chromosome undetermined scaffold_141, w... 34 6.1
UniRef50_Q6BUR4 Cluster: Similar to CA4464|IPF9828 Candida albic... 34 6.1
UniRef50_UPI0000DB797F Cluster: PREDICTED: similar to CG4840-PA;... 34 8.1
UniRef50_UPI00006CC842 Cluster: hypothetical protein TTHERM_0028... 34 8.1
UniRef50_Q6TUT7 Cluster: 78R; n=7; Poxviridae|Rep: 78R - Yaba mo... 34 8.1
UniRef50_Q7NB81 Cluster: Cell division protein ftsZ; n=1; Mycopl... 34 8.1
UniRef50_Q1U9U0 Cluster: Isochorismatase hydrolase; n=2; Lactoba... 34 8.1
UniRef50_A0UW37 Cluster: Putative uncharacterized protein precur... 34 8.1
UniRef50_Q9C9Y9 Cluster: Putative uncharacterized protein F17O14... 34 8.1
UniRef50_Q551M7 Cluster: Putative uncharacterized protein; n=2; ... 34 8.1
UniRef50_Q4UFK4 Cluster: Putative uncharacterized protein; n=1; ... 34 8.1
UniRef50_Q4U9U1 Cluster: Condensin subunit, putative; n=2; Theil... 34 8.1
UniRef50_Q23MK9 Cluster: Putative uncharacterized protein; n=1; ... 34 8.1
UniRef50_A5KBR7 Cluster: Putative uncharacterized protein; n=1; ... 34 8.1
UniRef50_A2FXH1 Cluster: Clan CA, family C19, ubiquitin hydrolas... 34 8.1
UniRef50_A2EQ83 Cluster: Putative uncharacterized protein; n=1; ... 34 8.1
UniRef50_Q2XW08 Cluster: Polyketide synthase 2; n=2; Cochliobolu... 34 8.1
UniRef50_Q6M0J7 Cluster: (2R)-phospho-3-sulfolactate synthase; n... 34 8.1
UniRef50_Q9P6L5 Cluster: Endocytosis protein end4; n=1; Schizosa... 34 8.1
>UniRef50_UPI0000D55F73 Cluster: PREDICTED: similar to RIKEN cDNA
6230410P16; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to RIKEN cDNA 6230410P16 - Tribolium castaneum
Length = 475
Score = 355 bits (872), Expect = 2e-96
Identities = 186/415 (44%), Positives = 263/415 (63%), Gaps = 14/415 (3%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+ E+E +L+ K+K G++++P G + ++++ EGA++N+PD A + AL+IK L+
Sbjct: 59 MALELEKLLKDKLKMGVVTVPKGIFENLEIQSSIKFIEGARNNIPDEEALSGALEIKALV 118
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
L KDDLL+VLISGGGSALLPLP+ P+TL EK L+++L+ GADI ELN VRK IS L
Sbjct: 119 ESLEKDDLLIVLISGGGSALLPLPRPPVTLTEKQNLIRELSTRGADILELNCVRKQISVL 178
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGG LA A P++V+SLILSD+VGDPLD IASGPT N D A+ ++ KY + L
Sbjct: 179 KGGGLAELAFPSRVISLILSDVVGDPLDFIASGPTTPNCDNGKDAITIINKYKCYEGLSA 238
Query: 181 SVQTLLENNGDNLVFPT------NNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVT 234
+++ +L +N FP + N++IG+N+I+ +AA + ++S VT
Sbjct: 239 AMRAVLGQKRENCYFPPVKDGKYEHVDNFVIGNNQIAAEAARQHAASFGFQSTIISTSVT 298
Query: 235 GNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCL 294
GNV ++ Y+ L IC + D L++ ++ S D + ++ K +C+
Sbjct: 299 GNVAQISQIYADLARTICNSSSKQTLKDFLETCGLCVDPSAVDTLISFDL----AKEICV 354
Query: 295 ILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAG 354
I GE TV V G+GKGGRNQQLALE S L+K+ + DI LSAGTDGIDGPTDAAG
Sbjct: 355 IAAGEPTVVVNGSGKGGRNQQLALELSVRLNKL--NIKSADISFLSAGTDGIDGPTDAAG 412
Query: 355 AIGYLNLISESTADGLDVDKYLANNDTYNFF-KLFKNDHLHVFTGHTNTNVMDIH 408
AIG +L++ S + + D YL NND+Y F+ K + +HL + GHT TNVMDIH
Sbjct: 413 AIGTSDLVNNSLEENIKPDDYLNNNDSYTFYSKYLQGEHL-IKIGHTGTNVMDIH 466
>UniRef50_A7SEK0 Cluster: Predicted protein; n=4; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 501
Score = 316 bits (777), Expect = 5e-85
Identities = 177/428 (41%), Positives = 254/428 (59%), Gaps = 29/428 (6%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYF--------------EGAKDNLPD 46
M+R VE++L I G+ SIP G D +S N ++ EGAK NLPD
Sbjct: 77 MARAVEDVLGHNIIRGVASIPCGLQDAIKESGNEDFIKSTLLRPGSPIHIIEGAKHNLPD 136
Query: 47 NSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGAD 106
+ AQ A +I+N+ TQ+ ++D+LLVLISGGGSALLP P ITL+EK+ +K +A+SG
Sbjct: 137 DRAQYAATQIQNIATQVTENDILLVLISGGGSALLPSPIDAITLQEKLKTIKAVASSGGT 196
Query: 107 IKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAV 166
I +LNTVRK +S LKGG+LA A PA+VV+LILSD++GDPLD+IASGPTV + +
Sbjct: 197 IVDLNTVRKNLSKLKGGKLAQLAYPAKVVTLILSDVIGDPLDIIASGPTVPDQSNPRDCL 256
Query: 167 DVLKKYNLIDALPKSVQTLLENNGDNLVFPTN------NTSNYIIGSNKISTKAAVVQCI 220
++ +K + +PKSV L+ D + N N ++G+N+I+ KAA +
Sbjct: 257 EIFRKLKAEEKVPKSVMQYLQGMADQPKPESQNNREFANVHNVLVGTNRIAVKAAAAEAA 316
Query: 221 ELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKV 280
L Y P++ S + G +V ++ L ++ L + + N + T V
Sbjct: 317 NLGYTPIIASTTLEGEAGEVGKSFANLASIA-------LTGNPIPGNSPVADKDLTSENV 369
Query: 281 LNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFD-IFIL 339
+N+IK +KPLC+I GE TV +KGTGKGGRNQ++ L + + + + + D + L
Sbjct: 370 INQIK-GAQKPLCVIGAGETTVTIKGTGKGGRNQEMVLSSALLMQQAQQIFSKEDGVVFL 428
Query: 340 SAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGH 399
SAGTDG DGPT AAGA+ + ++E+T GL +++ NND+Y F+ F N HV TG
Sbjct: 429 SAGTDGQDGPTPAAGALATPSQVNEATKHGLSAQEFIDNNDSYTFYSNFLNGRDHVVTGL 488
Query: 400 TNTNVMDI 407
T TNVMDI
Sbjct: 489 TGTNVMDI 496
>UniRef50_Q17JZ2 Cluster: Glycerate kinase; n=2; Culicidae|Rep:
Glycerate kinase - Aedes aegypti (Yellowfever mosquito)
Length = 486
Score = 309 bits (758), Expect = 1e-82
Identities = 179/424 (42%), Positives = 264/424 (62%), Gaps = 19/424 (4%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVF--------NKSRNVEYFEGAKDNLPDNSAQNT 52
M+ +++ IL ++ G ISIP+G+L+ F +KS N+ EGA++NLPD A
Sbjct: 57 MAVQIDRILGERLASGCISIPIGTLERFKDDFEFQLSKSTNIVVIEGARNNLPDVKAVEA 116
Query: 53 ALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNT 112
A KIK L + DD+L VL+SGGGSALLPLPK+P+TL+E + ++K LA++GA I+ELN
Sbjct: 117 ARKIKCLAEGMTDDDILCVLVSGGGSALLPLPKTPVTLDEILSVIKLLASAGASIEELNV 176
Query: 113 VRKVISDLKGGQLAVKAQPA-QVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKK 171
VR ++SD+KGG+LA+ A+ + +++S I+SDIVGDP+ LIASGPTVQ A+++L+K
Sbjct: 177 VRILLSDVKGGKLALAAKHSHKLLSFIISDIVGDPIPLIASGPTVQANVTNKAALNILEK 236
Query: 172 YNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSN 231
Y+L D +P SV ++ ++ + ++IGSNKI+ + V + + + L L++
Sbjct: 237 YHLSDKMPHSVVKIIHHSDPKRSKVPGDI--HLIGSNKIAIECVVSEASKTGIVALPLTS 294
Query: 232 KVTGNVQDVANKYSKLVTVICKYLRQNLE----IDELKSNIKKLEISGTDLKVLNEIKIS 287
V GNV + Y++L I K+ + E I + K L + L EI +
Sbjct: 295 SVQGNVAPLGKAYAELAANIRKFQDNSTEKHAFIKTVAQLGKSLHYDSSKATELAEIISN 354
Query: 288 N-KKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGI 346
N +K L L+ GGE TV V+G G GGRNQ+LAL FS + +D D+ +LSAGTDGI
Sbjct: 355 NPRKDLLLVAGGEPTVVVQGHGSGGRNQELALRFSLECWQKQDPSLQ-DVILLSAGTDGI 413
Query: 347 DGPTDAAGAIGYLNLISE--STADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNV 404
DGPT+AAGAIG ++ + + A V ++ +ND+ F+KL N H+ TGHT TNV
Sbjct: 414 DGPTEAAGAIGGAGVVEQFNAMASQKFVLGFIEDNDSNTFYKLVGNGKYHIVTGHTGTNV 473
Query: 405 MDIH 408
MD+H
Sbjct: 474 MDLH 477
>UniRef50_Q8IVS8 Cluster: Glycerate kinase; n=31; Euteleostomi|Rep:
Glycerate kinase - Homo sapiens (Human)
Length = 523
Score = 305 bits (749), Expect = 1e-81
Identities = 183/426 (42%), Positives = 246/426 (57%), Gaps = 20/426 (4%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKS----------RNVEYFEGAKDNLPDNSAQ 50
M+ E +L + G+IS+P G ++ V+ FEGA+DNLPD A
Sbjct: 93 MAAAAEELLGQHLVQGVISVPKGIRAAMERAGKQEMLLKPHSRVQVFEGAEDNLPDRDAL 152
Query: 51 NTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKEL 110
AL I+ L L DDLLLVLISGGGSALLP P P+TLEEK L + LA GA I+EL
Sbjct: 153 RAALAIQQLAEGLTADDLLLVLISGGGSALLPAPIPPVTLEEKQTLTRLLAARGATIQEL 212
Query: 111 NTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLK 170
NT+RK +S LKGG LA A PAQVVSLILSD+VGDP+++IASGPTV ++ + +L
Sbjct: 213 NTIRKALSQLKGGGLAQAAYPAQVVSLILSDVVGDPVEVIASGPTVASSHNVQDCLHILN 272
Query: 171 KYNLIDALPKSVQTLLENNGDNLVFP--TNNTSNYIIGSNKISTKAAVVQCIELNYLPLV 228
+Y L ALP+SV+T+L + P + N IIGSN ++ A Q L Y +V
Sbjct: 273 RYGLRAALPRSVKTVLSRADSDPHGPHTCGHVLNVIIGSNVLALAEAQRQAEALGYQAVV 332
Query: 229 LSNKVTGNVQDVANKYSKLVTVICKYLRQNL------EIDELKSNIKKLEISGTDLKVLN 282
LS + G+V+ +A Y L V L ++ E +L +L+I L+
Sbjct: 333 LSAAMQGDVKSMAQFYGLLAHVARTRLTPSMAGASVEEDAQLHELAAELQIPDLQLEEAL 392
Query: 283 EIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAG 342
E + P+CL+ GGE TV ++G+G+GGRNQ+LAL L + L D+ LS G
Sbjct: 393 ETMAWGRGPVCLLAGGEPTVQLQGSGRGGRNQELALRVGAELRRW--PLGPIDVLFLSGG 450
Query: 343 TDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNT 402
TDG DGPT+AAGA L S++ A+GLD+ +LA+ND++ FF + + TG T T
Sbjct: 451 TDGQDGPTEAAGAWVTPELASQAAAEGLDIATFLAHNDSHTFFCCLQGGAHLLHTGMTGT 510
Query: 403 NVMDIH 408
NVMD H
Sbjct: 511 NVMDTH 516
>UniRef50_Q9VQC4 Cluster: Glycerate kinase; n=2; Sophophora|Rep:
Glycerate kinase - Drosophila melanogaster (Fruit fly)
Length = 487
Score = 291 bits (713), Expect = 3e-77
Identities = 167/413 (40%), Positives = 241/413 (58%), Gaps = 9/413 (2%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNK--SRNVEYFEGAKDNLPDNSAQNTALKIKN 58
M+ +V+ L + G++S+P+ +L F + + + EGA +NLPD +A A +IK
Sbjct: 74 MANKVQQDLGATSAGGVLSVPVNTLKQFQQPVAPGLVVHEGAANNLPDENALKAAREIKQ 133
Query: 59 LITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVIS 118
L ++ D+L V ISGGGSALLPLP+SP+TLE+K + KL GA I+E+N VR S
Sbjct: 134 LAEKMTAQDILFVFISGGGSALLPLPRSPLTLEDKRSIADKLMKRGASIQEINAVRIACS 193
Query: 119 DLKGGQLA-VKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDA 177
D+KGG+LA + Q +V+ +LSDI+GDPL+LIA GPT+Q + A D+LKK+++ +
Sbjct: 194 DIKGGRLARLAGQAGLLVTFVLSDIIGDPLELIACGPTIQ-PEAAASPSDILKKHHVWEE 252
Query: 178 LPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNV 237
L ++ + E + +++GSN I+T A + L Y+P VLS V G+V
Sbjct: 253 LSPEIRRVFEQPEEQKNTSLPEHKVFVVGSNVIATSTAAHEAERLGYIPCVLSCAVQGDV 312
Query: 238 QDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILG 297
VA Y +L+ I + + + +L+ E S + E +S+KKPL LI G
Sbjct: 313 AQVAGDYQRLLHGIQEAKQHGILDPQLREKYAFGERSYPTFRRALEDHMSSKKPLFLICG 372
Query: 298 GEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIG 357
GE + V G G GGR+Q LAL S+ LH+ + D LSAGTDGIDGPTDAAGA G
Sbjct: 373 GEPVIKVSGHGLGGRSQHLALLMSQALHRDEAMR---DCTFLSAGTDGIDGPTDAAGAFG 429
Query: 358 YLNLISESTADGL--DVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDIH 408
+++ D ++ + L N D+YNF+K HV TGHT TNVMD+H
Sbjct: 430 DSSVVESYLGDHTLDELAETLRNCDSYNFYKNLAQGEHHVLTGHTGTNVMDLH 482
>UniRef50_UPI00015B42A9 Cluster: PREDICTED: hypothetical protein;
n=1; Nasonia vitripennis|Rep: PREDICTED: hypothetical
protein - Nasonia vitripennis
Length = 539
Score = 264 bits (646), Expect = 4e-69
Identities = 171/382 (44%), Positives = 235/382 (61%), Gaps = 25/382 (6%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLD--VFNKSRNVEYFEGAKDNLPD-NSAQNTALKIK 57
M+ +E +L ++K GIIS+P S N+S VEY EGA+ N PD NSA +T L I
Sbjct: 68 MAHSLEKLLGRRLKRGIISVPRCSKMHCEANRSSVVEYREGAEHNQPDANSAASTEL-IV 126
Query: 58 NLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVI 117
L+ L ++D LL LISGGGSALL PK P+T E K L ++L N+GA I ELN VRK++
Sbjct: 127 ELVENLTENDTLLTLISGGGSALLFSPKPPMTAETKGQLCRRLQNAGAGIAELNHVRKLL 186
Query: 118 SDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPT--VQNTDGANKAVDVLKKYNLI 175
S +KGG LA A PA+V++L+LSDI+GDP++ IASGPT + + A+D+L+KYNL
Sbjct: 187 SKVKGGGLAKSAYPARVLALVLSDIIGDPIESIASGPTCPLGAENPGRAAIDILRKYNLY 246
Query: 176 DALPKSVQTLL----ENNG-DNLVFPT---NNTSNYIIGSNKISTKAAVVQCIELNYLPL 227
D L + V+ LL EN +N + + N IIGSN + +AA + ++
Sbjct: 247 DDLEEDVKNLLLKADENKSKENTILDKGKFKHVENIIIGSNSTALQAAEAAARDYDFDSA 306
Query: 228 VLSNKVTGNVQDVANKYSKLVTVICKYL------RQNLEIDELKSNIKKLEISGTDLKVL 281
VLS+ V G+V++V+ Y+KL + C L +Q+ K NI+ L++S L+
Sbjct: 307 VLSSVVEGDVKNVSYAYAKLAHIACHALENKFSDKQDFMAAVEKENIEILKVSSEKLEKA 366
Query: 282 NEI--KISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFS-KYLHKV-KD-QLNDFDI 336
E + K + L+ GGE TV VKG+GKGGRNQ+LAL FS +L ++ KD L + +
Sbjct: 367 FETLSGLGKGKGIVLLSGGEPTVVVKGSGKGGRNQELALRFSLDWLSEIAKDPTLAKYFV 426
Query: 337 FILSAGTDGIDGPTDAAGAIGY 358
LSAGTDG DGPTDAAGA GY
Sbjct: 427 LFLSAGTDGQDGPTDAAGAFGY 448
>UniRef50_Q4RX75 Cluster: Chromosome 11 SCAF14979, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 11 SCAF14979, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 431
Score = 259 bits (634), Expect = 1e-67
Identities = 152/343 (44%), Positives = 211/343 (61%), Gaps = 13/343 (3%)
Query: 76 GGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVV 135
GGSALLP P P++L+EK+ + +KLA +GA I+ELNTVR+ +S LKGG LA A+PAQV+
Sbjct: 85 GGSALLPAPIPPVSLQEKLDVTRKLAAAGATIQELNTVRRALSLLKGGGLAQCARPAQVI 144
Query: 136 SLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLEN-----NG 190
+LILSD++GDPLDLIASGPTV + V ++Y L+++LP SV +L + +
Sbjct: 145 ALILSDVIGDPLDLIASGPTVLAEVSPEGVLSVFERYKLLNSLPASVMEVLRSPTLRKST 204
Query: 191 DNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTV 250
D P + N +IGSN ++ K A ++ EL +LP+VL+ V G+V+ VA Y L
Sbjct: 205 DQPEAP-GHVLNVVIGSNSLALKCAGLRARELGFLPVVLAPGVCGDVRAVAKLYGLLARF 263
Query: 251 ICKYLRQNLEIDELKSNI-KKLEISGTDL----KVLNEIKISNKKPLCLILGGEITVAVK 305
C + EI + ++ K++ + DL KVLNE + CL+ GGE TV +
Sbjct: 264 ACSPDKPPPEITQGILDLGKEVGVQSWDLCRTMKVLNEGRTEGWGATCLLAGGEPTVELT 323
Query: 306 GTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISES 365
G G+GGRNQ+LAL L + +Q D +F LS GTDG DGPT+AAGA+ L+ ES
Sbjct: 324 GMGQGGRNQELALRVGWELRGL-EQPPDGPVF-LSGGTDGQDGPTEAAGALTDAGLLGES 381
Query: 366 TADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDIH 408
A GLD++ +L NND+Y FF + G T TNVMD+H
Sbjct: 382 QAQGLDIESFLMNNDSYTFFSRLSAGKRLLVPGLTCTNVMDVH 424
>UniRef50_A1RWN7 Cluster: Hydroxypyruvate reductase; n=1;
Thermofilum pendens Hrk 5|Rep: Hydroxypyruvate reductase
- Thermofilum pendens (strain Hrk 5)
Length = 459
Score = 216 bits (527), Expect = 1e-54
Identities = 150/414 (36%), Positives = 219/414 (52%), Gaps = 47/414 (11%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+ +E +L +I G+IS+P ++ +K + GA + +I + +
Sbjct: 72 MAVGIEKVLGDRISGGVISVPEDLVESVSKQLSRIQVVGATHPRASRKSVEAGERIVSTV 131
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
L ++D ++ L SGGGSAL LP + +EE L KL +GADI ELNTVRK +S
Sbjct: 132 RGLREEDTVIALFSGGGSALAELPAEGVDIEELGELSVKLMKAGADIVELNTVRKHLSRF 191
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGG LA A PA VV+L++SD+VGD +D IASGPTV + AV V++KY L D+LP+
Sbjct: 192 KGGWLAKHAYPAAVVALLISDVVGDRMDTIASGPTVPDPTTYQDAVAVIRKYRLEDSLPQ 251
Query: 181 SVQTLLENNGDNLVFPT--------NNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNK 232
S++ +LE+ L T + N II SN +S A + + Y ++L++
Sbjct: 252 SIRRILEDGLKGLAPETPKPGDPAFSRVHNRIIASNTLSLNAMAEKAKAMGYNTVILTSL 311
Query: 233 VTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPL 292
+ G ++VA K++ I K + LK N + P
Sbjct: 312 LEGEAREVA----KVLAAIAKEV----------------------LKTGNPVS----PPA 341
Query: 293 CLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDA 352
++ GGE TV VKG G GGRNQ+LAL + L V D+ + ++S G+DG DGPTD
Sbjct: 342 VILAGGETTVTVKGKGLGGRNQELALSAAIALKGV-DR-----VALVSIGSDGRDGPTDV 395
Query: 353 AGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMD 406
AGA+ + A G+ ++YL NND+YNFF++ HV TG+T TNV D
Sbjct: 396 AGAVVDGYTYQRALAKGVRPEEYLENNDSYNFFRVVGG---HVKTGYTGTNVND 446
>UniRef50_Q09235 Cluster: Uncharacterized protein C13B9.2; n=2;
Caenorhabditis|Rep: Uncharacterized protein C13B9.2 -
Caenorhabditis elegans
Length = 397
Score = 212 bits (518), Expect = 1e-53
Identities = 139/410 (33%), Positives = 230/410 (56%), Gaps = 35/410 (8%)
Query: 6 ENILQSKIKYGIISIPMGSLDVFNKSRN-VEYFEGAKDNLPDNSAQNTALKIKNLITQLN 64
+ + S ++ I+ P + N+ N E GA+DNLPD + K+ + I +
Sbjct: 7 DQLKSSLLQKTIVIAPEQQKGIENELENDTEILYGARDNLPDEKSVFATRKVISEIRDFD 66
Query: 65 KDD-LLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGG 123
+ + L LISGGGSALL P +P+ L EK+ ++ + GA I+ELNT+R+ +SD+KGG
Sbjct: 67 SESTIFLFLISGGGSALLTSPSAPLDLAEKLETIRIMQAHGATIQELNTIRQNLSDVKGG 126
Query: 124 QLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAV--DVLK--KYNLIDALP 179
+L + + ++LI+SD++G+P++LIASGPTV +K + ++L+ K N ++ LP
Sbjct: 127 KLLREIKKGCSIALIISDVIGNPVELIASGPTVIPAHQQDKFIISNILESLKINKLE-LP 185
Query: 180 KSVQTLLENN-GDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQ 238
+V+ +LEN+ + L T+ N+II SN + +AA Y ++++ ++GN
Sbjct: 186 VNVKNVLENHEKEQLPENTSRFQNFIISSNNFALRAAAEYLTSSGYNSTIVTSSLSGNAA 245
Query: 239 DVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILGG 298
++ K+++++T + I+ + L + + I N P+ L+ GG
Sbjct: 246 EIGKKFAEIIT--------------------EKSITSSHLLKNSNLTIEN-YPIALLFGG 284
Query: 299 EITVAV-KGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIG 357
E TV + + GKGGRNQ++ L L +K ++ + LSAGTDG DGPTDAAGAI
Sbjct: 285 ETTVHLSENPGKGGRNQEMVL---SCLDALKTRVPAHNFTFLSAGTDGQDGPTDAAGAI- 340
Query: 358 YLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
++ L+ ++L N+D+YNF++ FK H+ TG + TNVMDI
Sbjct: 341 -ISNEDLPLNSLLNSSEFLQNSDSYNFWRQFKGGANHILTGPSGTNVMDI 389
>UniRef50_Q648E2 Cluster: Putative glycerate kinase; n=1; uncultured
archaeon GZfos3D4|Rep: Putative glycerate kinase -
uncultured archaeon GZfos3D4
Length = 469
Score = 210 bits (513), Expect = 5e-53
Identities = 148/398 (37%), Positives = 215/398 (54%), Gaps = 44/398 (11%)
Query: 13 IKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVL 72
I G++ IP G + ++ E A+ +P + A ++ + + ++DLL L
Sbjct: 107 IDEGVVVIPHGQGG--ERPPGMDIIE-AEHPVPAQGSLTAANRVLEMAEKSTENDLLFAL 163
Query: 73 ISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPA 132
ISGGGS+LL P ITLEEKI +L SG I E+NTVRK IS +KGG+LA A PA
Sbjct: 164 ISGGGSSLLAKPVDGITLEEKIESTNQLLKSGCTINEMNTVRKHISAIKGGKLAEAASPA 223
Query: 133 QVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENN--G 190
+ LILSD++GDP+D IASGPT Q+T +A VL+KY L +P+ ++ ++E
Sbjct: 224 TTIGLILSDVLGDPVDFIASGPTAQDTTTFKQAQGVLEKYGLWTRIPEHMRGVIERGIEK 283
Query: 191 DNLVFPTN-NTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVT 249
+ + T+ T N+IIGSN I++ AA+ + L Y L+L+ + G ++VA K+ T
Sbjct: 284 ERVTKKTSVETHNFIIGSNYIASHAAMEKVKTLGYNSLLLTTHLEGESKEVA----KVFT 339
Query: 250 VICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILGGEITVAVKGTGK 309
+ K +++S+ L P +I GGE TV V G G+
Sbjct: 340 ALMK---------DIRSHDTPLS-----------------PPAAVIAGGETTVTVTGNGR 373
Query: 310 GGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADG 369
GGRNQ+ L + + + D+ + I S GTDGIDG +DAAGAI + ++
Sbjct: 374 GGRNQEFVLSAAMTIPQDNDR-----VVIASMGTDGIDGMSDAAGAIADGFTLKRASEAE 428
Query: 370 LDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
L+ D YL NND+ FF + ND L TG T TNV D+
Sbjct: 429 LNPDAYLRNNDSNTFF-VKLNDAL--ITGRTGTNVNDV 463
>UniRef50_Q1PYP3 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 454
Score = 192 bits (467), Expect = 2e-47
Identities = 139/408 (34%), Positives = 216/408 (52%), Gaps = 38/408 (9%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+ VE +L KIK GI+++ G + A +PD+S N +I ++
Sbjct: 78 MAAAVEKLLGDKIKKGIVNVRYG----YTTPCKYVKLNPAGHPIPDSSGINGTKEIIDIA 133
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
+ N+DDL+ LISGGGSAL LP + I+LEE + L GA I E+N +RK +S +
Sbjct: 134 KEANEDDLVFCLISGGGSALFELPYAGISLEEIKEITASLLKCGATIDEMNAIRKHLSLV 193
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGG+ A + A+++S+ILSD++ DPL+ IASG T + +L KYNL +P
Sbjct: 194 KGGRFAGLCK-AEMISVILSDVINDPLETIASGATSPDPSTFQDCEWILNKYNLHHKIPV 252
Query: 181 SVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDV 240
S+Q ++N V T + I +++S ++ I N L S + G +
Sbjct: 253 SIQQHIQNGIHGYVEETPKPGDKIF--DRVSN---II--IGNNRTALAASKEKGGQLG-- 303
Query: 241 ANKYSKLVTVICKYLRQNLEIDELKSNIKKL-EISGTDLKVLNEIKISNKKPLCLILGGE 299
Y+ L+ C +K +++ ++ G + ++ ++P C+I GGE
Sbjct: 304 ---YNTLILSSC-----------IKGEAREIAKVFGAIAREIHASGCPAERPACIIAGGE 349
Query: 300 ITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYL 359
TV VKG G GGR+Q+ +L + + + D L ILSAGTDG+DG T+AAGA+
Sbjct: 350 STVTVKGNGLGGRSQEFSLSAAIEIDGLADTL------ILSAGTDGMDGNTEAAGAMVDG 403
Query: 360 NLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
I + + L +KYL NND+++FFK + + L + TG T TNVMD+
Sbjct: 404 TTIINAKSKKLHPEKYLLNNDSFSFFK--ETNEL-IVTGPTKTNVMDV 448
>UniRef50_A5UUT0 Cluster: Hydroxypyruvate reductase; n=4;
Chloroflexaceae|Rep: Hydroxypyruvate reductase -
Roseiflexus sp. RS-1
Length = 458
Score = 191 bits (466), Expect = 3e-47
Identities = 139/378 (36%), Positives = 194/378 (51%), Gaps = 46/378 (12%)
Query: 34 VEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEK 93
VE E A LPD +I L+TQL + DL+L LISGGGSALL P I+L++
Sbjct: 111 VELLE-AGHPLPDTRGVAAGERIAALLTQLGERDLVLALISGGGSALLTRPAPGISLDDM 169
Query: 94 IGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASG 153
L L GA I E+NT+R+ + LKGG LA A PA V++L+LSD+VGDPLD+IASG
Sbjct: 170 QKLTGVLLACGASINEINTLRRHLDTLKGGGLARLAAPATVITLVLSDVVGDPLDVIASG 229
Query: 154 PTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNN--------TSNYII 205
PTV + A+DVL++YN++ P ++ LE+ + T N II
Sbjct: 230 PTVADPTTFADALDVLERYNVLHQTPVAILRRLESGVRGEIAETPKPGDPALARVGNLII 289
Query: 206 GSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELK 265
GSN+++ +AA+ + L+L T +Q A +++ I + E+
Sbjct: 290 GSNRLAAEAALAAAHREGFNALIL----TTFLQGEARVVGRVLAAIAR---------EIA 336
Query: 266 SNIKKLEISGTDLKVLNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLH 325
N + + +P C+I GGE TV ++G G+GGRNQ+LAL
Sbjct: 337 DNNRPIS-----------------RPACVIAGGETTVTLRGDGRGGRNQELALA------ 373
Query: 326 KVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFF 385
V D +++ TDG DGPTDAAGA+ + + GLDV LA ND+Y FF
Sbjct: 374 AVADLAAAPGALLVALATDGGDGPTDAAGAVVSAATLQRARDLGLDVAAALARNDSYPFF 433
Query: 386 KLFKNDHLHVFTGHTNTN 403
D L + HTN N
Sbjct: 434 DAL-GDLLRPGSTHTNVN 450
>UniRef50_A3DMH9 Cluster: MOFRL domain protein; n=1; Staphylothermus
marinus F1|Rep: MOFRL domain protein - Staphylothermus
marinus (strain ATCC 43588 / DSM 3639 / F1)
Length = 390
Score = 182 bits (444), Expect = 1e-44
Identities = 142/415 (34%), Positives = 227/415 (54%), Gaps = 52/415 (12%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+ +E IL + I+ G+I+IP D++ K ++ E A +P+ + A KI ++
Sbjct: 1 MALAIERILGNLIEKGVIAIPYYMSDLY-KLEKIQLVE-AGHPIPNEGSIKAAEKILDIA 58
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
+ ++D+L+ LISGGGSAL+ P PITL++ K L SGADI+E+N VRK +S++
Sbjct: 59 GKAGENDVLISLISGGGSALMEKPIQPITLDDLKITNKLLLESGADIREINIVRKHLSEI 118
Query: 121 KGGQLAVKAQPAQ-VVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALP 179
KGG+LAVKA A+ +VSL++SD+ GD + IASGPTV ++ A +VL++Y+L D +P
Sbjct: 119 KGGRLAVKAGKAKYIVSLMISDVPGDNPEYIASGPTVPDSSTYIDAKNVLERYDLWDKVP 178
Query: 180 KSVQTLLEN--NGDNLVFPTNN------TSNYIIGSNKISTKAAVVQCIELNYLPLVLSN 231
+SV+ ++E G+ P ++ T N II SN + + Y P +L+
Sbjct: 179 ESVRIVIEKGIRGEIEETPKHDHPVFRKTINKIIASNYTVLRKLSEYFRDKGYTPYILTT 238
Query: 232 KVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKP 291
++ G ++ E+ ++ ++I ++IS DL +KP
Sbjct: 239 RLEG---------------------ESSEVGKVLASI-AMDISDRDL--------LGQKP 268
Query: 292 LCLILGGEITVAVKGT--GKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGP 349
L L+LGGE V++KG GKGGR Q+L L F L + + D+ I++ TDG+DG
Sbjct: 269 LVLLLGGEPNVSLKGQRYGKGGRCQELVLSF---LATTRGRR---DLSIIAFDTDGVDGF 322
Query: 350 TDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNV 404
+DAAGA G + + + YL +++Y FF+ + + TG T TNV
Sbjct: 323 SDAAGAYGDYEVWENMSKNRDSPWSYLREHNSYEFFRKYNG---LIITGPTGTNV 374
>UniRef50_Q2LX73 Cluster: Glycerate dehydrogenase / hydroxypyruvate
reductase; n=1; Syntrophus aciditrophicus SB|Rep:
Glycerate dehydrogenase / hydroxypyruvate reductase -
Syntrophus aciditrophicus (strain SB)
Length = 438
Score = 177 bits (431), Expect = 4e-43
Identities = 120/369 (32%), Positives = 192/369 (52%), Gaps = 45/369 (12%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
+PD+ + A I + L++DD + L+SGG SAL+ P P+++ + K L +
Sbjct: 100 IPDSRSAAAAEMIIKGLAGLSEDDFFIYLLSGGTSALIEKPLPPLSIADLQETSKLLLRA 159
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
G + +N VRK +S +KGG+L + A+ V L++SD++GD L+ I S P ++
Sbjct: 160 GVPVDGMNAVRKHLSLIKGGRLG-RMTKARGVVLVISDVIGDDLETIGSAPLYKDRSSGR 218
Query: 164 KAVDVLKKYNLIDALPKSVQTLLENN--GDNLVFPTNNT---SNYIIGSNKISTKAAVVQ 218
++L +Y L + LP V+ L+E G+ P +++IGSN+ + K A ++
Sbjct: 219 DVCEILSRYGLWEKLPPVVRNLMERTRAGEQEETPKEENPRIDHFVIGSNRKALKKAKMK 278
Query: 219 CIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDL 278
L ++++++ G +DVA K + + + +RQ E SN+
Sbjct: 279 AESLGMKTWIMTSRLHGEARDVA----KALIALGREIRQTRE----SSNL---------- 320
Query: 279 KVLNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFI 338
P+CL+ GGE TV V+G GKGGRNQ+L L K + + + +
Sbjct: 321 ------------PVCLLFGGETTVTVRGNGKGGRNQELCLAALKEIGNIP------GLLL 362
Query: 339 LSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTG 398
LSAGTDGIDG T+AAGA+ + + GL +D +L ND++ FFK + L + TG
Sbjct: 363 LSAGTDGIDGNTEAAGALADAEISKRAGELGLSIDDFLERNDSFRFFK--QTGGL-IVTG 419
Query: 399 HTNTNVMDI 407
T TNVMDI
Sbjct: 420 PTGTNVMDI 428
>UniRef50_Q04S94 Cluster: Glycerate kinase; n=3; Leptospira|Rep:
Glycerate kinase - Leptospira borgpetersenii serovar
Hardjo-bovis (strain JB197)
Length = 453
Score = 172 bits (418), Expect = 2e-41
Identities = 132/413 (31%), Positives = 202/413 (48%), Gaps = 36/413 (8%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M++ +L+ +I GII G K +E E PD ++ +KI L
Sbjct: 63 MAQAAYEVLRPQIFAGIILTKYGHSSG-KKFPPLEILEAGHPT-PDVNSVLGGMKILELC 120
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
+ L +D LVL+SGGGSAL+ +P + LE+ I KL SGA+I+ +NT+R ++S +
Sbjct: 121 SHLQPEDTALVLLSGGGSALMEVPAPGLDLEDLIVWNSKLLASGANIQNINTIRILLSSI 180
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGG L K P++ ++LILSD++GD L +ASGPT+ + + + K+YNL ++
Sbjct: 181 KGGGLLSKILPSKSITLILSDVLGDDLSKVASGPTIHSIIEKKSILRIFKQYNL--SIEP 238
Query: 181 SVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDV 240
++ +L L + N KI ++ + + N +T ++ V
Sbjct: 239 KIKAVLRKK-TKLAPESLKRENDSESPGKIDNTKGFIKIDPQRNIVYCIGN-ITQAIESV 296
Query: 241 ANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILGGEI 300
+ L + +L +L + ++ I+ ++K + PL ++ GGE
Sbjct: 297 QEECRNL-NIPVLFLTSSLSCEAKEAGFFLGSIARENIK-------TTTSPLLILCGGET 348
Query: 301 TVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLN 360
TV G+GKGGRNQ+LAL FS+ + K I +LS TDG DGPTDAAGAI
Sbjct: 349 TVTHDGSGKGGRNQELALAFSQQISDCK------GITLLSLATDGTDGPTDAAGAI---- 398
Query: 361 LISESTADGLDVDKYLANND------TYNFFKLFKNDHLHVFTGHTNTNVMDI 407
DG K ND T+N +++ K VFTG T TNV DI
Sbjct: 399 ------VDGTTWKKISKTNDARISLKTHNSYEVLKRADSLVFTGATGTNVNDI 445
>UniRef50_UPI0000DB7A11 Cluster: PREDICTED: similar to CG9886-like;
n=1; Apis mellifera|Rep: PREDICTED: similar to
CG9886-like - Apis mellifera
Length = 458
Score = 163 bits (397), Expect = 6e-39
Identities = 118/389 (30%), Positives = 200/389 (51%), Gaps = 27/389 (6%)
Query: 1 MSREVENILQSKIKYGIISIPMGSL-------DVFNK-SRNVEYFEGAKDNLPDNSAQNT 52
MS E I+ +++ G + +P S+ + F + + Y E D PD +
Sbjct: 1 MSSAFERIVGKQLRKGWMVVPRKSIFMMWSFPEAFPPLNSRITYIEAGTDGNPDEKSVRA 60
Query: 53 ALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNT 112
+I N + +L K DLL+V++S LL P+ ITL +K+ ++ +L + A +E+N
Sbjct: 61 TRQIINYVKKLKKRDLLIVMLSQEIDDLLCCPRDTITLRDKLRVLTRLNKAEATPEEINI 120
Query: 113 VRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKY 172
VR +S ++GG LA A PA++V LI S++ P+ + GP + + A KA+++L KY
Sbjct: 121 VRNKLSAIRGGDLARFAYPARIVILITSNVSDKPMTHLLGGPCIYDPK-AEKALEILTKY 179
Query: 173 NLIDALPKSVQTLLENN------GDNLVFPTNN---TSNYIIGSNKISTKAAVVQCIELN 223
LID +P S++ L+E D + N ++I N + + ++ +L
Sbjct: 180 KLIDRVPLSIKELVEETVPWIMAADKQLDADKNYKFVREFVIACNADAMECMAMESYKLG 239
Query: 224 YLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISG-TDLKVLN 282
P+ L++ G++Q+ A +Y K+ +++ + + E+ ++ I TD KV N
Sbjct: 240 LFPIKLNSTCFGDIQEFAREYVKMTSLMILAVEGKINKLEMWQEMRDSPICPLTDEKV-N 298
Query: 283 EIKISNKK---PLCLILGGEITVAVKGT-GKGGRNQQLALEFSKYLHKVKDQ---LNDFD 335
EI + K LCL+LGG TV + T G+GG NQ+LAL FS Y + Q L +
Sbjct: 299 EIFPAKDKWGLGLCLLLGGRPTVNLCPTPGRGGPNQELALYFSLYWYLRTQQYPILRGYT 358
Query: 336 IFILSAGTDGIDGPTDAAGAIGYLNLISE 364
++ L + G DG +DA GA GY +L ++
Sbjct: 359 VWFLGGSSYGKDGNSDAVGAFGYQSLSTD 387
>UniRef50_A3H6I3 Cluster: Hydroxypyruvate reductase; n=1; Caldivirga
maquilingensis IC-167|Rep: Hydroxypyruvate reductase -
Caldivirga maquilingensis IC-167
Length = 445
Score = 161 bits (392), Expect = 2e-38
Identities = 127/383 (33%), Positives = 191/383 (49%), Gaps = 46/383 (12%)
Query: 30 KSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPIT 89
KS NVE E LP + + A +I L L++ DL L+LISGGGSAL+ LP+ P+T
Sbjct: 90 KSSNVEVIESTHP-LPSDLSIKAAEEIIELSRTLSRGDLALILISGGGSALVELPRPPLT 148
Query: 90 LEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLA--VKAQPAQVVSLILSDIVGDPL 147
+++ + L + + NSG I E+NTVRK +S +KGGQLA + +VV L +SD+ GD
Sbjct: 149 IDDLVELNRLMLNSGMSISEINTVRKHVSMIKGGQLAQYFIKRGVRVVGLYVSDVPGDDP 208
Query: 148 DLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTN---NTSNYI 204
LIASGPTV + + AV +LK + +LP V+ LLEN + T N +
Sbjct: 209 SLIASGPTVPDKSSFSDAVSILKARGIWGSLPDKVKVLLENGVRGSIPETPKRLKAMNKV 268
Query: 205 IGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDEL 264
I +N K+ ++ EL ++L++++ G ++V + ++ +D L
Sbjct: 269 ILTNLNVLKSLRLRLSELGVKSIILTSRLEGEAREVGKALA------------SITLDSL 316
Query: 265 KSNIKKLEISGTDLKVLNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYL 324
+ L + + ++ +P + G G G GR +LA F+K +
Sbjct: 317 RRG----------LLLKRGVVLAGGEPTVTVRG-------NGRG--GRTMELAAAFAKSV 357
Query: 325 HKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNF 384
+ +L+ TDGIDG TDAAGA S + + GL +D L+ NDTY
Sbjct: 358 S------GHGSVALLALATDGIDGNTDAAGAYADYTTESRAMSIGLSIDDALSRNDTYTL 411
Query: 385 FKLFKNDHLHVFTGHTNTNVMDI 407
FK ND + TG T T V I
Sbjct: 412 FKAL-ND--TIITGPTGTQVNTI 431
>UniRef50_Q7UK87 Cluster: Putative uncharacterized protein; n=1;
Pirellula sp.|Rep: Putative uncharacterized protein -
Rhodopirellula baltica
Length = 487
Score = 150 bits (364), Expect = 6e-35
Identities = 121/371 (32%), Positives = 186/371 (50%), Gaps = 38/371 (10%)
Query: 43 NLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLAN 102
N P +A +I L+ DL++ LISGGGSALL P I+L++K+ + + L++
Sbjct: 134 NEPTVAAIEGTDRILQLVADAGPRDLVIGLISGGGSALLCRPSPGISLDDKLTVTRWLSS 193
Query: 103 SGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGA 162
GADI LNTVRK +SD+KGG L + Q ++L+LSD++GDPLDLIASGPTV +T A
Sbjct: 194 HGADIVALNTVRKHLSDVKGGGLLRANRAGQFLTLVLSDVLGDPLDLIASGPTVPDTSTA 253
Query: 163 NKAVDVLKKYNLIDALPKSVQTLLENNGDN--LVFPTNNTSNYIIGSNKISTKAAVVQCI 220
A+ VL +++ LP V+ L+ D+ + S +++G+N ++ AA +
Sbjct: 254 MDALAVLDRFDPDHQLPHVVREHLKQAADHPASTIAATDHSTFVLGNNAVAVDAAGITAE 313
Query: 221 ELNYLPLVLSNKVT-GNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLK 279
L Y ++ ++ + G+ + V + L + L+ D
Sbjct: 314 ALGYNHVMHCHRQSEGDAESVGRHLADLTLTM-------LQADPAVHR------------ 354
Query: 280 VLNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFD---I 336
+ +S +P + I +G G GRN QL L + Y ++ L D +
Sbjct: 355 --QDAFLSGGEPTVSLADASI----RGVG--GRNGQLVL--AAYARLLELNLTDDQWSRL 404
Query: 337 FILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVF 396
ILS GTDG DGP+DAAG + ++ GLDV + ND++ F + +
Sbjct: 405 AILSGGTDGEDGPSDAAGGMIDGDVHRRIMELGLDVHDAMRRNDSHGFLRQVGG---LLL 461
Query: 397 TGHTNTNVMDI 407
TG T TNV DI
Sbjct: 462 TGPTGTNVCDI 472
>UniRef50_Q0G2B9 Cluster: MOFRL domain protein; n=1; Fulvimarina
pelagi HTCC2506|Rep: MOFRL domain protein - Fulvimarina
pelagi HTCC2506
Length = 431
Score = 144 bits (348), Expect = 5e-33
Identities = 84/240 (35%), Positives = 129/240 (53%), Gaps = 4/240 (1%)
Query: 9 LQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDL 68
+Q K+K G+ + V V+ + G P ++ A I+ + DL
Sbjct: 71 VQDKLKAGVAVTTQDAAKVI---AGVDTYVGGHPT-PTEGSEKGAEAIEAAADSAEEGDL 126
Query: 69 LLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVK 128
+LVL+SGGGSALL P +TLE+KI + L GA I E+NTVR+ +S LKGG L +
Sbjct: 127 VLVLVSGGGSALLTAPAEGLTLEDKIAVNDALLGCGAPIDEINTVRRKLSRLKGGGLLKR 186
Query: 129 AQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLEN 188
A PA+V+SLILSD+ GD +ASGP+V D A+D++++Y + D +P++ L
Sbjct: 187 AAPARVLSLILSDVPGDDPKSVASGPSVPPADMPEAALDIVQRYGIEDRIPEAALARLRG 246
Query: 189 NGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLV 248
++ F + I+GSN +S AA EL Y+ + + G+V D A + +L+
Sbjct: 247 TSEDQDFSSQEFETVIVGSNSLSCDAAEAAAEELGYVTDRVDGWLDGDVADAAQRLRELL 306
Score = 83.8 bits (198), Expect = 8e-15
Identities = 54/121 (44%), Positives = 72/121 (59%), Gaps = 6/121 (4%)
Query: 287 SNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGI 346
S KP+ +I GGE TV ++G G GGRNQ++A+ F+ L + + D+ +F LS GTDG
Sbjct: 311 SGGKPIAIIAGGETTVVLRGGGTGGRNQEMAMRFA-MLAEAEPISGDW-VF-LSGGTDGR 367
Query: 347 DGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMD 406
DGPT+AAGAI + GLD + LA+ND+ L D L V TG T TNV D
Sbjct: 368 DGPTNAAGAIVDRETLDRMRQSGLDPEAKLADNDSNP--ALEAADAL-VKTGATGTNVAD 424
Query: 407 I 407
+
Sbjct: 425 V 425
>UniRef50_A3ZMR6 Cluster: Putative uncharacterized protein; n=2;
Planctomycetaceae|Rep: Putative uncharacterized protein
- Blastopirellula marina DSM 3645
Length = 459
Score = 142 bits (345), Expect = 1e-32
Identities = 85/223 (38%), Positives = 131/223 (58%), Gaps = 8/223 (3%)
Query: 6 ENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEG--AKDNLPDNSAQNTALKIKNLITQL 63
E+++Q+K G++S+P D +E G A N P + +I + ++ L
Sbjct: 77 EDLMQAKRLRGLLSVPA---DCVRPLSRIELRGGRPAAVNSPTAAGVQITSEILDRVSNL 133
Query: 64 NKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGG 123
+ DL + LISGGGSALL P + ITL +K + + L+++GADI +LNTVRK +S +KG
Sbjct: 134 RERDLCIALISGGGSALLTAPVAGITLADKQAITQYLSSAGADIVQLNTVRKQLSRVKGN 193
Query: 124 QLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK--S 181
LAV Q+VSLI+SD++GDPLD+IASGPT+ N A A+ VL+ + D LP+ S
Sbjct: 194 GLAVACNAGQLVSLIISDVLGDPLDIIASGPTIPNPSTAADALQVLQDFGASD-LPQFAS 252
Query: 182 VQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNY 224
+ +L++ PT N++IG+N ++ AA ++ Y
Sbjct: 253 IVAVLKSQQPAAPQPTCVVHNFVIGNNAVAVDAAGIEAERRGY 295
Score = 74.9 bits (176), Expect = 4e-12
Identities = 54/124 (43%), Positives = 67/124 (54%), Gaps = 10/124 (8%)
Query: 289 KKPLCLILGGEITVAVKGT---GKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDG 345
K P CLI GGE V + G GGRNQQL L + L + I ILS GTDG
Sbjct: 327 KGPDCLITGGEPVVQLAAEAERGLGGRNQQLTLAAYQRLCEASPAQPMDGIAILSGGTDG 386
Query: 346 IDGPTDAAGAIGYLNLISESTADG--LDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTN 403
DGPTDAAGA +++ A+ L + YL ND Y+FF+ D L + TG T+TN
Sbjct: 387 EDGPTDAAGA--WIDAAGAKQANNRQLAANDYLRRNDAYHFFEPL--DRL-LKTGPTHTN 441
Query: 404 VMDI 407
V D+
Sbjct: 442 VCDL 445
>UniRef50_UPI0000DB723F Cluster: PREDICTED: similar to CG9886-like;
n=1; Apis mellifera|Rep: PREDICTED: similar to
CG9886-like - Apis mellifera
Length = 499
Score = 141 bits (341), Expect = 4e-32
Identities = 79/167 (47%), Positives = 110/167 (65%), Gaps = 11/167 (6%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYF-----------EGAKDNLPDNSA 49
M+ +E++L + +K GIISIP S + +S + YF EG+ +N PD +
Sbjct: 51 MAVVLEHMLGNYLKDGIISIPSASTEALWESEDKSYFPLLESGVIKYCEGSTNNQPDERS 110
Query: 50 QNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKE 109
T +I +L+ L ++D L+VLISGGGSALL +P+ I E+K+ + K L N+GADIKE
Sbjct: 111 LETTHQIIDLVESLTENDTLIVLISGGGSALLYMPRPVIDFEDKLYISKMLQNAGADIKE 170
Query: 110 LNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTV 156
+N VR +S +KGG LA A PA ++SLILSDIVGDP++ IASGPTV
Sbjct: 171 VNIVRSKLSMVKGGGLARMAYPASIISLILSDIVGDPVESIASGPTV 217
Score = 140 bits (338), Expect = 8e-32
Identities = 82/210 (39%), Positives = 127/210 (60%), Gaps = 14/210 (6%)
Query: 207 SNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKS 266
+N ++ +A+ ++ P++L + V GNV DV+ Y+ + ++IC L + LE +E +
Sbjct: 220 NNTVAVEASSLEACNYKLTPIILRSDVVGNVHDVSLAYAHITSLICLALDKTLEKEEFFA 279
Query: 267 NIKKLEISGTDLKVLNEIK--ISN--KKPLCLILGGEITVAVKGTGKGGRNQQLALEFS- 321
+K + + ++EI I N ++ L LI GGE TV VKG GKGGRNQ+LAL FS
Sbjct: 280 KVKDIPVLSLPATKVDEIYNLIDNVSEEGLVLIGGGEPTVVVKGKGKGGRNQELALYFSL 339
Query: 322 KYLHKVK--DQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANN 379
+L K+K + +++++ +LSAGTDG DGPTDAAGA GY ++ + L +N
Sbjct: 340 DWLTKIKAYPRFSEYEVIMLSAGTDGQDGPTDAAGAFGYPAIVERMLPENT-----LEDN 394
Query: 380 DTYNFFKLFKNDHLHVF-TGHTNTNVMDIH 408
++YN + F+ L +F TG T TNVMD+H
Sbjct: 395 NSYNLYSRFRKG-LDLFKTGFTGTNVMDLH 423
>UniRef50_A1IFB6 Cluster: Hydroxypyruvate reductase; n=2;
Bacteria|Rep: Hydroxypyruvate reductase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 452
Score = 138 bits (334), Expect = 3e-31
Identities = 89/261 (34%), Positives = 133/261 (50%), Gaps = 12/261 (4%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+ VE ++ ++ G++S+ G + K+ E EG +PD A +I L
Sbjct: 70 MAAAVETLMGDRLTGGLLSVKYGHTHLLQKT---ELGEGGHP-IPDAGGLKNAQRILALA 125
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
+K DL++ L+SGGGSALLPLP ITL +K + +L GA I E+NT+RK +S +
Sbjct: 126 QSASKKDLVICLLSGGGSALLPLPAPGITLADKQAAMHELLACGATITEINTLRKHLSAI 185
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGG LA PA ++ L++SD+VGD L IASGPTV + + ++ Y L + LP
Sbjct: 186 KGGLLARAVFPATLLCLVISDVVGDDLSTIASGPTVADPTTFADCLRIIDTYQLKNRLPA 245
Query: 181 SVQTLLENNGDNLVFPT--------NNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNK 232
SV ++ L T +I N + AA + L Y L+LS+K
Sbjct: 246 SVIHHIQKGAAGLKTETPKPGDPVFEKVVTHICADNTAALAAAADKARRLGYQTLILSSK 305
Query: 233 VTGNVQDVANKYSKLVTVICK 253
+ G +DVA + + I K
Sbjct: 306 MEGKTRDVARMHGTMAKEILK 326
Score = 100 bits (240), Expect = 6e-20
Identities = 56/117 (47%), Positives = 72/117 (61%), Gaps = 9/117 (7%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
P CL+ GGE TV ++G GKGGRNQ+ L + + + K I +LS GTDG DGPT
Sbjct: 334 PACLLSGGETTVTIRGAGKGGRNQEFCLALTDDIAEHKH------IVVLSGGTDGTDGPT 387
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
DAAGA+ S + GL YLA+ND++ FFK K + L + TG TNTNVMD+
Sbjct: 388 DAAGAVVSNRTASRAAQAGLTPAHYLADNDSFTFFK--KLNSL-LITGPTNTNVMDL 441
>UniRef50_Q0W1M0 Cluster: Putative hydroxypyruvate reductase; n=1;
uncultured methanogenic archaeon RC-I|Rep: Putative
hydroxypyruvate reductase - Uncultured methanogenic
archaeon RC-I
Length = 453
Score = 138 bits (333), Expect = 3e-31
Identities = 91/248 (36%), Positives = 129/248 (52%), Gaps = 12/248 (4%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+ E+EN+L +I G+++ G ++R A LP Q ++ +++
Sbjct: 75 MAAELENLLGDRITAGLVNDRYGVQARTTRTR----VNNAGHPLPTEDGQRGVREMLDML 130
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
+ +KDDL++ LISGGGSALLP P I+LE+KI L L SGA I E+N VRK S +
Sbjct: 131 SGASKDDLVIFLISGGGSALLPCPAPGISLEDKIRLTDLLLKSGATIAEINCVRKHSSCI 190
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGGQL A V+SLI+SD+VGD IASGPT + A+ +L Y L D P
Sbjct: 191 KGGQLLRYVNGATVLSLIVSDVVGDDPGSIASGPTAPDNTTFADALSILDNYGLKDLAPV 250
Query: 181 SVQTLLENNGDNLVFPT--------NNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNK 232
S+ LE V T N II N ++ KAA + L Y P++L +
Sbjct: 251 SILRHLEAGMRGQVPETLKPGDPAFGRVYNEIIAGNLVALKAAAGEAQRLGYHPIILGSH 310
Query: 233 VTGNVQDV 240
+ G ++V
Sbjct: 311 IKGESREV 318
Score = 78.6 bits (185), Expect = 3e-13
Identities = 49/119 (41%), Positives = 66/119 (55%), Gaps = 15/119 (12%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFD--IFILSAGTDGIDG 348
P +I GGE TV V+G GKGGRN++ L L D+ I +SA TDGIDG
Sbjct: 339 PAAIISGGETTVTVRGPGKGGRNEEFILGV----------LRDYTPGITAVSADTDGIDG 388
Query: 349 PTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
TDA GAI + + + GL + K L +N +Y+FF+ + +FTG T TNV D+
Sbjct: 389 ATDACGAIADETTLPRAESLGLSIQKALDSNASYDFFEALGD---LIFTGPTGTNVSDL 444
>UniRef50_Q5V6W3 Cluster: Putative hydroxypyruvate reductase; n=1;
Haloarcula marismortui|Rep: Putative hydroxypyruvate
reductase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 444
Score = 134 bits (325), Expect = 3e-30
Identities = 119/373 (31%), Positives = 173/373 (46%), Gaps = 56/373 (15%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
LP + I + + + + L+L +++GG SALL P +TLE+ +L +
Sbjct: 109 LPSDQNVAATADILETVDEADAETLILFVLTGGASALLSAPAGDLTLEDLQTTTDRLLSG 168
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
G I E+N VRK +SDLKGGQ+A +A PA V L++SD+VG+ L I SGP+V +
Sbjct: 169 GVPIAEINAVRKHLSDLKGGQIARRAAPATVAGLLISDVVGNDLSTIGSGPSVPDETTYE 228
Query: 164 KAVDVLKKYNLIDALPKSVQTLLENNGDNLV----FPTNN----TSNYIIGSNKISTKAA 215
A DV ++Y+L P +V LE+ D V FP + +N++IG N + AA
Sbjct: 229 DARDVFERYDLTP--PPAVCNYLESGRDGRVSETPFPDDTDFDRVTNHLIGDNATALDAA 286
Query: 216 VVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISG 275
E Y PLVL T ++ A + +K + I + E +
Sbjct: 287 AAVAREAGYEPLVL----TSRLRGEAREVAKPLVAIAE------------------EATA 324
Query: 276 TDLKVLNEIKISNKKPLCLILGGEITVAVKGTG-KGGRNQQLALEFSKYLHKVKDQLNDF 334
T V + P L+ GGE TV V G G +GG NQ+ L + +D
Sbjct: 325 TGTPV--------EPPAVLLAGGETTVTVTGDGGQGGPNQEFVLSGAL--------AHDG 368
Query: 335 DIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLH 394
D I + TDG DG +D AGAI IS D + L ND ++ +
Sbjct: 369 DAVIAAVDTDGEDGSSDVAGAIADGAAIS----DRERAREALLANDVGSYLSEIE---AT 421
Query: 395 VFTGHTNTNVMDI 407
+ TG T TNV D+
Sbjct: 422 IETGPTGTNVNDV 434
>UniRef50_Q8G2G7 Cluster: Hydroxypyruvate reductase, putative; n=28;
Proteobacteria|Rep: Hydroxypyruvate reductase, putative
- Brucella suis
Length = 428
Score = 132 bits (320), Expect = 1e-29
Identities = 76/216 (35%), Positives = 128/216 (59%), Gaps = 10/216 (4%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
+PD + + ++ N ++ L++DDL++ LISGGGSALLP P +TLE++I + K L S
Sbjct: 94 VPDGAGLAASRRLFNAVSGLSEDDLVVALISGGGSALLPSPPEGMTLEDEIAVNKALLAS 153
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
GA I +N VRK +S +KGG+LA A PA+V SL++SDI GD +ASGPTV + +
Sbjct: 154 GAPISAMNAVRKHLSTIKGGRLAAAAHPAKVFSLVVSDIPGDNPAFVASGPTVPDETSRD 213
Query: 164 KAVDVLKKYNLIDALPKSVQTLLENNG------DNLVFPTNNTSNYIIGSNKISTKAAVV 217
+A+ ++++Y L LP++ +++ D+ VF N +I S +S +AA
Sbjct: 214 EALKIIERYRL--DLPQAALAHIKSENAHAPQPDDGVFARNEVR--VIASAAVSLEAAAR 269
Query: 218 QCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICK 253
+ ++LS+ V G ++VA+ ++ + + +
Sbjct: 270 EASRHGVEAVILSDSVEGEAREVAHVHAAIAREVAE 305
Score = 57.2 bits (132), Expect = 8e-07
Identities = 90/332 (27%), Positives = 141/332 (42%), Gaps = 36/332 (10%)
Query: 98 KKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQ 157
++L N+ + + E + V +IS GG A+ P + + L D + L+ASG +
Sbjct: 104 RRLFNAVSGLSEDDLVVALIS---GGGSALLPSPPE--GMTLEDEIAVNKALLASGAPIS 158
Query: 158 NTDGANKAVDVLKKYNLIDAL-PKSVQTLLENN--GDNLVF----PT--NNTSN----YI 204
+ K + +K L A P V +L+ ++ GDN F PT + TS I
Sbjct: 159 AMNAVRKHLSTIKGGRLAAAAHPAKVFSLVVSDIPGDNPAFVASGPTVPDETSRDEALKI 218
Query: 205 IGSNKISTKAAVVQCI--ELNYLPLVLSNKVTGN-VQDVANKYSKLVTVICKYLRQNLEI 261
I ++ A + I E + P N V+ +A+ L + R +E
Sbjct: 219 IERYRLDLPQAALAHIKSENAHAPQPDDGVFARNEVRVIASAAVSLEAAAREASRHGVEA 278
Query: 262 DELKSNIK--KLEISGTDLKVLNEIKISN---KKPLCLILGGEITVAVKGTG-KGGRNQQ 315
L +++ E++ + E+ + KKP+ ++ GGE TV + G KGGRN +
Sbjct: 279 VILSDSVEGEAREVAHVHAAIAREVAERDRPFKKPVVILSGGETTVTIGSPGGKGGRNSE 338
Query: 316 LALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKY 375
L F+ + + I L+A TDGIDG D AGA +S G D
Sbjct: 339 FLLSFALDIDGYAN------IHALAADTDGIDGSEDNAGAFADGGTVSRLQKLGEDGMAR 392
Query: 376 LANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
L ND + F + L V G T TNV D+
Sbjct: 393 LNANDAWTAFDALGD--LFV-PGPTGTNVNDL 421
>UniRef50_A7D4B1 Cluster: Hydroxypyruvate reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Hydroxypyruvate reductase
- Halorubrum lacusprofundi ATCC 49239
Length = 580
Score = 132 bits (320), Expect = 1e-29
Identities = 80/212 (37%), Positives = 118/212 (55%), Gaps = 10/212 (4%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
LP +A ++ + + DDL+L +I+GGGSALL P PI++ + L L S
Sbjct: 216 LPSERGVESARRVLDAAERAGPDDLVLAVITGGGSALLAAPADPISVGDLRALTSALLTS 275
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
GA I E+N VRK S +KGGQLA A PA V+L +SD++GDPLD IASGPTV +
Sbjct: 276 GASIDEINAVRKHCSAVKGGQLARAAAPATTVTLAVSDVIGDPLDTIASGPTVPDPSTYA 335
Query: 164 KAVDVLKKYNLIDALPKSVQTLLENNGDNLV--FPT------NNTSNYIIGSNKISTKAA 215
A+ VL +Y+L DA P SV+ L D + PT + ++ +++G+ + + AA
Sbjct: 336 DALAVLDRYDL-DA-PDSVRERLRAGADGELPETPTAGDPAFDRSAAFVVGNGRTALDAA 393
Query: 216 VVQCIELNYLPLVLSNKVTGNVQDVANKYSKL 247
+ Y PLVLS V G ++ ++ +
Sbjct: 394 ATAAADRGYEPLVLSASVRGEAREAGTTHAAI 425
Score = 45.6 bits (103), Expect = 0.002
Identities = 29/72 (40%), Positives = 39/72 (54%), Gaps = 8/72 (11%)
Query: 336 IFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHV 395
+ + SA TDG+DGPTDAAGAI + A LD D D ++ + LF + +
Sbjct: 501 VVVASADTDGLDGPTDAAGAI--------ADATTLDPDAARDALDRHDAYPLFDDAGALL 552
Query: 396 FTGHTNTNVMDI 407
TG T TNV D+
Sbjct: 553 RTGPTGTNVNDL 564
>UniRef50_Q12DK9 Cluster: Hydroxypyruvate reductase; n=6;
Proteobacteria|Rep: Hydroxypyruvate reductase -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 438
Score = 132 bits (319), Expect = 2e-29
Identities = 80/224 (35%), Positives = 126/224 (56%), Gaps = 7/224 (3%)
Query: 32 RNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLE 91
+ +E E A +PD + A +I + L DDL+L LISGGGS+LL LP +TLE
Sbjct: 89 QRIELVEAAHP-VPDAAGLAAAQRILAMTQGLTADDLVLCLISGGGSSLLTLPAEGLTLE 147
Query: 92 EKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIA 151
+K + K L NSGA+I E+N VRK +S +KGG+LA PA+V++L +SD+ GD +IA
Sbjct: 148 DKQRINKDLLNSGANIGEMNCVRKHLSRIKGGRLAAACAPARVITLTISDVPGDDPSIIA 207
Query: 152 SGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSN----YIIGS 207
SGPTV + +AV +L +Y + A+P + +LLE P + N ++I +
Sbjct: 208 SGPTVPDASTCAEAVAILARYGI--AIPGGLMSLLEQGALETPKPGDAAFNGHEVHMIAT 265
Query: 208 NKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVI 251
+ S +AA + +LS+++ G ++V ++ L +
Sbjct: 266 PQQSLEAAAAVARDAGLTAYILSDEMEGESREVGKVHAALARAV 309
Score = 66.1 bits (154), Expect = 2e-09
Identities = 44/124 (35%), Positives = 65/124 (52%), Gaps = 15/124 (12%)
Query: 289 KKPLCLILGGEITVAVK----GT--GKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAG 342
+KP ++ GGE TV +K GT G+GGR + + + L ++ L+A
Sbjct: 317 QKPCVILSGGETTVTIKKQPDGTPKGRGGRAGEFCMGLALGLQ------GQAGVYALAAD 370
Query: 343 TDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNT 402
TDGIDG D AGA + + + A G+ +++YL ND Y +F+ + V TG TNT
Sbjct: 371 TDGIDGVEDNAGAFVAPDTLERALAKGMKLNRYLDRNDAYGYFEPLGD---LVITGPTNT 427
Query: 403 NVMD 406
NV D
Sbjct: 428 NVND 431
>UniRef50_A7CF57 Cluster: Hydroxypyruvate reductase; n=10;
Proteobacteria|Rep: Hydroxypyruvate reductase -
Ralstonia pickettii 12D
Length = 669
Score = 132 bits (318), Expect = 2e-29
Identities = 112/372 (30%), Positives = 178/372 (47%), Gaps = 49/372 (13%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
+PD + + A +I + + L + D L+VL+SGGGS+LL LP I + + + ++L
Sbjct: 331 VPDEAGEQAAQEILDRVCALTERDRLIVLVSGGGSSLLSLPAEGIPMADLKAVTRELLRC 390
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
GA I ++N VRK +S ++GG+LA A A V +LI+SD+ GD IASGPTV +
Sbjct: 391 GAPITDMNIVRKHLSRIQGGRLAA-ASRAPVTTLIVSDVAGDDPSAIASGPTVPDASTYA 449
Query: 164 KAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNN--------TSNYIIGSNKISTKAA 215
A+ ++K++ +P +V+ LE + T +N++I + + S +A
Sbjct: 450 DALAIIKRWGA--QIPDTVRAHLERGARGEIAETPKPGDACFARVTNHVIATAQQSLQAG 507
Query: 216 VVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISG 275
+L + VTG A + +++ + + +RQ+ G
Sbjct: 508 AQVFATRGIHTAILGDTVTGE----AREVAQVYGALARQVRQH----------------G 547
Query: 276 TDLKVLNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFD 335
T P+ LI GGE TV + GGR + A ++L + L D D
Sbjct: 548 TPFVA----------PVALISGGECTVTIPPGLTGGRGGRCA----EFLLSLGVTLEDMD 593
Query: 336 -IFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLH 394
++ L+A TDGIDG D AGA+ I+ + A+G+ L +D Y FF H
Sbjct: 594 NVYALAADTDGIDGSEDNAGALLDPESIARAAANGVGARAALDAHDAYGFFAA---AHDL 650
Query: 395 VFTGHTNTNVMD 406
+ TG T TNV D
Sbjct: 651 IVTGPTRTNVND 662
>UniRef50_Q1AS62 Cluster: Hydroxypyruvate reductase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep: Hydroxypyruvate
reductase - Rubrobacter xylanophilus (strain DSM 9941 /
NBRC 16129)
Length = 428
Score = 131 bits (317), Expect = 3e-29
Identities = 94/252 (37%), Positives = 129/252 (51%), Gaps = 11/252 (4%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+R E IL ++ G++ G K+ Y A PD A + L
Sbjct: 57 MARAAEQILGDRLSGGLVVTKDGHRPG-PKTLKTLY---ASHPEPDGRGLQAARSVAGLA 112
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
+ L + DLLL L+SGG SALL P I LEE L L SGADI E+N VRK +S L
Sbjct: 113 SSLGEGDLLLALVSGGASALLADPAEGIGLEELKRLTGDLLRSGADIGEINAVRKHVSTL 172
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGG LA A PA+V++L+LSD+VGD + IASGPT + A +VL++Y ID P+
Sbjct: 173 KGGGLARLASPARVLALLLSDVVGDDISSIASGPTAPDPTTLEDAREVLRRYG-IDP-PE 230
Query: 181 SVQTLLENNGDNLVFPTN----NTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGN 236
V L G P + +N + G + S +AA + EL Y L+LS +TG
Sbjct: 231 GVARRL-REGPETPKPEDPLFRRVTNVVCGGGRASVEAATRRARELGYGALLLSTTLTGE 289
Query: 237 VQDVANKYSKLV 248
+ A ++ +V
Sbjct: 290 ARGAAAVHAAMV 301
Score = 57.6 bits (133), Expect = 6e-07
Identities = 43/117 (36%), Positives = 56/117 (47%), Gaps = 9/117 (7%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
P L+ GGE+TV+V+G G GG NQ+ L + L V SA TDG DGPT
Sbjct: 314 PCALLSGGELTVSVRGAGTGGPNQEFCLALAVELEGVAGWA------AFSADTDGQDGPT 367
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
AAG + + G+D + L ND + L L + TG T TNV D+
Sbjct: 368 GAAGGLVDGETARRAREAGIDPREALDRNDAH--AALAAAGAL-LETGPTGTNVNDL 421
>UniRef50_A0LQ82 Cluster: MOFRL domain protein; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: MOFRL domain protein -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 443
Score = 131 bits (316), Expect = 4e-29
Identities = 81/253 (32%), Positives = 135/253 (53%), Gaps = 12/253 (4%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M++ VE++L ++ G I++ G K+ +E A +PD + + +
Sbjct: 64 MAKAVEDVLGDRLAAGWITVKYGHGLSLKKTHVME----AGHPIPDEAGLEATRTLLARL 119
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
+ ++ DL++ + SGGGSALLP P ++LEEK + + L GA I E+N VRK +S
Sbjct: 120 GECSEHDLVVGVFSGGGSALLPAPCPAVSLEEKKEITRLLLECGASIDEINAVRKHLSRS 179
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGG LA A PA VVSL+LSD++GD D+IASGPT + A++++++Y L +
Sbjct: 180 KGGGLAKAAHPATVVSLLLSDVIGDRPDVIASGPTAPDVSTFADALEIIERYGLTGKIST 239
Query: 181 SVQTLLENNGDNLVFPTNNTS--------NYIIGSNKISTKAAVVQCIELNYLPLVLSNK 232
+V L + + T N ++G+N+ + AA + L + LVLS+
Sbjct: 240 NVLGRLNDGAAGRLEETPKPGDPLFAGLLNLVVGNNRAALNAAADRARALGFHTLVLSSG 299
Query: 233 VTGNVQDVANKYS 245
+ G ++VA ++
Sbjct: 300 IRGEAREVAKVFA 312
Score = 94.3 bits (224), Expect = 5e-18
Identities = 57/117 (48%), Positives = 74/117 (63%), Gaps = 9/117 (7%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
P C++ GGE TV V+G GKGGR+Q+LAL F+ + + D+L +L+AGTDG DGPT
Sbjct: 328 PACILSGGEPTVTVRGPGKGGRSQELALAFAIAVDGL-DRLA-----LLAAGTDGTDGPT 381
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
DAAGA + S + GL ++LA ND+YNFF D L TG T TNVMD+
Sbjct: 382 DAAGAFADGHTCSRALRLGLIPREFLARNDSYNFFAPI--DQLFK-TGPTRTNVMDL 435
>UniRef50_Q9X1S1 Cluster: Glycerate kinase, putative; n=7;
Bacteria|Rep: Glycerate kinase, putative - Thermotoga
maritima
Length = 417
Score = 129 bits (311), Expect = 2e-28
Identities = 69/174 (39%), Positives = 108/174 (62%), Gaps = 3/174 (1%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M++ +L KI+ G++ G + + E +E A +PD + T ++ L+
Sbjct: 52 MAKAAYEVLGKKIRKGVVVTKYGHSE--GPIDDFEIYE-AGHPVPDENTIKTTRRVLELV 108
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
QLN++D +L L+SGGGS+L LP ++LEE L L SGA I+E+NTVRK +S +
Sbjct: 109 DQLNENDTVLFLLSGGGSSLFELPLEGVSLEEIQKLTSALLKSGASIEEINTVRKHLSQV 168
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNL 174
KGG+ A + PA+VV+L+LSD++GD LD+IASGP ++ + A+ VL+KY +
Sbjct: 169 KGGRFAERVFPAKVVALVLSDVLGDRLDVIASGPAWPDSSTSEDALKVLEKYGI 222
Score = 104 bits (250), Expect = 4e-21
Identities = 104/320 (32%), Positives = 151/320 (47%), Gaps = 35/320 (10%)
Query: 107 IKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAV 166
+ +LN V+ L GG ++ P + VSL +I L+ SG +++ + K +
Sbjct: 108 VDQLNENDTVLFLLSGGGSSLFELPLEGVSL--EEIQKLTSALLKSGASIEEINTVRKHL 165
Query: 167 DVLKKYNLIDAL-PKSVQTLLENN--GDNL-------VFPTNNTSN---YIIGSNKISTK 213
+K + + P V L+ ++ GD L +P ++TS ++ I T
Sbjct: 166 SQVKGGRFAERVFPAKVVALVLSDVLGDRLDVIASGPAWPDSSTSEDALKVLEKYGIETS 225
Query: 214 AAVVQCIELNYLPLVLSN---KVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKK 270
+V + I L P LSN + GNVQ V ++ L K N EI + +
Sbjct: 226 ESVKRAI-LQETPKHLSNVEIHLIGNVQKVCDEAKSLA----KEKGFNAEIITTSLDCEA 280
Query: 271 LEISGTDLKVLNEIKISN---KKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKV 327
E ++ E+K + KKP LI GGE V VKG G GGRNQ+LAL + L +
Sbjct: 281 REAGRFIASIMKEVKFKDRPLKKPAALIFGGETVVHVKGNGIGGRNQELALSAAIALEGI 340
Query: 328 KDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKL 387
+ + + SAGTDG DGPTDAAG I + A G D +YL NND+YN K
Sbjct: 341 EG------VILCSAGTDGTDGPTDAAGGIVDGSTAKTLKAMGEDPYQYLKNNDSYNALK- 393
Query: 388 FKNDHLHVFTGHTNTNVMDI 407
K+ L + TG T TNV D+
Sbjct: 394 -KSGAL-LITGPTGTNVNDL 411
>UniRef50_A4WI53 Cluster: Hydroxypyruvate reductase; n=4;
Thermoprotei|Rep: Hydroxypyruvate reductase -
Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length = 442
Score = 128 bits (308), Expect = 4e-28
Identities = 83/249 (33%), Positives = 129/249 (51%), Gaps = 6/249 (2%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+ + I I G++ P G N+ VE +G LP + ++ +
Sbjct: 71 MAEALVEIFGDLIAGGVVITPTGG----NRVGPVEVLKG-NHPLPGEDTLKASKRLLEYL 125
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
++ + D + V ISGGGSAL +P+ + L E L +L GADI ELNTVRK +S +
Sbjct: 126 QEVREGDTVFVAISGGGSALFEVPEEGVELGEIAKLSDELMKRGADIVELNTVRKRLSAV 185
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGG+L + +VVSLI+SD+VGD LD IASGPT + AV VLKKY L D+LP+
Sbjct: 186 KGGKLLRNIKARRVVSLIVSDVVGDRLDTIASGPTAPDATDKTFAVAVLKKYGLWDSLPE 245
Query: 181 SVQTLLENNGDNLVFPT-NNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQD 239
++ L+E P + N + +N S + A + Y ++L++ + G ++
Sbjct: 246 RLRRLIEIETPKAGDPLFDKVINVPVVNNLGSLQKAAERLALRGYNTIILTSMLEGEARE 305
Query: 240 VANKYSKLV 248
V + ++
Sbjct: 306 VGRVLASVI 314
Score = 73.7 bits (173), Expect = 8e-12
Identities = 41/117 (35%), Positives = 63/117 (53%), Gaps = 10/117 (8%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
P+ ++ GGE V V+G G+GGRNQ++ L + + + TDGIDG +
Sbjct: 327 PVAILAGGETVVTVRGRGRGGRNQEMCLSLAM-------AIRGLNATAACVATDGIDGNS 379
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
AAGA+ ++ E+ G++ +YL NND+Y FF+ + TG+T NV DI
Sbjct: 380 PAAGALIDGGVVEEAERLGVNPAEYLDNNDSYTFFEKLGR---AIITGYTGVNVNDI 433
>UniRef50_Q5LT50 Cluster: MOFRL domain protein; n=6;
Rhodobacteraceae|Rep: MOFRL domain protein -
Silicibacter pomeroyi
Length = 424
Score = 127 bits (307), Expect = 5e-28
Identities = 73/198 (36%), Positives = 107/198 (54%), Gaps = 3/198 (1%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
+PD + A +++ ++ + D++L LISGGGSALLP P +TL+ K L + L S
Sbjct: 98 VPDEIGHHAARRVREILAETTARDVVLALISGGGSALLPAPPDGVTLDHKQALNRLLLQS 157
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
G DI +N VR+ +S LKGG L A PA V + ILSD++GD L IASGPTV
Sbjct: 158 GLDINAVNAVRQHVSVLKGGGLLRHAAPAPVTAYILSDVIGDDLRAIASGPTVAPIASRA 217
Query: 164 KAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELN 223
+ D+L++ + DALP S++ L P N++IG N+ S AA
Sbjct: 218 EIRDLLERKGIADALPDSIRRHLRQ--PESAHPLPKAGNHLIGGNRESLAAAAAALTVFG 275
Query: 224 YLPLVLSNKVTGNVQDVA 241
+ V+ + G+V + A
Sbjct: 276 EVQ-VIDEPLVGDVGEAA 292
Score = 77.8 bits (183), Expect = 5e-13
Identities = 51/117 (43%), Positives = 64/117 (54%), Gaps = 6/117 (5%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
P LI GGE TV V+G+G GGRNQ+LAL + + +D LSAGTDG DGPT
Sbjct: 308 PQVLIWGGETTVRVRGSGIGGRNQELALRLAALM---EDTPLSRPWLFLSAGTDGRDGPT 364
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
+AAGA + A G + +LA ND+ + L D L TG T TNV D+
Sbjct: 365 EAAGACVDAGTLPRIRAAGAAPETFLARNDSNSALTL-SGDLL--VTGATGTNVADV 418
>UniRef50_Q0LLX8 Cluster: Hydroxypyruvate reductase; n=1;
Herpetosiphon aurantiacus ATCC 23779|Rep:
Hydroxypyruvate reductase - Herpetosiphon aurantiacus
ATCC 23779
Length = 442
Score = 127 bits (306), Expect = 6e-28
Identities = 86/266 (32%), Positives = 140/266 (52%), Gaps = 12/266 (4%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+ +E+IL +I G++ + F R ++ E + + PD N A + + +
Sbjct: 63 MAAALESILGERIDRGLVVVKDAHCGDFALKR-IQLLEASHPS-PDQRGLNAAQQCEIWL 120
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
Q DDL++ LISGG SALLP P ++L + L + L GA I+++NT+RK L
Sbjct: 121 QQAQADDLVIALISGGASALLPAPSGAMSLADLQTLTQLLLACGAPIEQINTIRKHCDRL 180
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGGQ A AQPA ++SL++SD+VG PL +IASG +V + +A +L++Y LID LP
Sbjct: 181 KGGQFAALAQPASLLSLVISDVVGSPLTIIASGLSVPDPASFAEAWAILEQYGLIDRLPL 240
Query: 181 SVQTLLE--NNGDNLVFPTN------NTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNK 232
S++ L+ G P N II N+I+ + A+ Q E ++ +
Sbjct: 241 SIRDYLQLGMRGAVPAHPDGSEPWWANVHTTIIARNEIA-QTAIKQLAEAQGWQVIHDQQ 299
Query: 233 -VTGNVQDVANKYSKLVTVICKYLRQ 257
+TG Q V + + + + + ++Q
Sbjct: 300 PITGEAQVVGQQVGQRLCQLAQSVQQ 325
Score = 53.2 bits (122), Expect = 1e-05
Identities = 45/130 (34%), Positives = 68/130 (52%), Gaps = 12/130 (9%)
Query: 281 LNEIKISNKKPLCLILGGEITVAVKGT---GKGGRNQQLALEFSKYLHKVKDQLNDFDIF 337
L ++ S ++P + GGE TV + G +GGRN +LAL + L D + I
Sbjct: 316 LCQLAQSVQQPTLYLAGGETTVNLAGILPHSQGGRNAELALAAALAL----DGCPNCQII 371
Query: 338 ILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFT 397
L+ TDG DG + AAGAI I+++ GLD + LA +D+YN ++ + +
Sbjct: 372 ALA--TDGGDGSSPAAGAIANGQSIAQARKLGLDPHQALAIHDSYNVWRALGS---AIEI 426
Query: 398 GHTNTNVMDI 407
G T TNV D+
Sbjct: 427 GPTLTNVNDL 436
>UniRef50_A4T037 Cluster: Hydroxypyruvate reductase; n=2;
Burkholderiaceae|Rep: Hydroxypyruvate reductase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 450
Score = 127 bits (306), Expect = 6e-28
Identities = 123/377 (32%), Positives = 183/377 (48%), Gaps = 56/377 (14%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
+PD + + A +I L QL + D+L+ L+SGGGS+LL LP+ I++E+ + L S
Sbjct: 108 VPDQAGMDGAKEILGLTNQLKQGDVLIALVSGGGSSLLTLPQEGISIEDMRRTTEALLRS 167
Query: 104 GADIKELNTVRKVISDLKGGQLAVKA--QPAQVVSLILSDIVGDPLDLIASGPTVQNTDG 161
GA I+E+N VRK +S + GG LA A + A+V +L++SD+ GD IASGP +
Sbjct: 168 GAPIEEMNVVRKHLSAILGGNLARVAIERGARVEALLISDVTGDSPADIASGPCAADYST 227
Query: 162 ANKAVDVLKKYNLID-ALPKSVQTLLENN--GD------NLVFPTNNTSNYIIGSNKIST 212
A+++L+KY L + ++P SV L+ G+ ++ + +N++I + S
Sbjct: 228 YLDALNILEKYRLDEQSIPVSVLNHLKQGLAGEKPETLKDIDLVSAQVANHVIATAYKSL 287
Query: 213 KAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLE 272
+AA Y P++L + +TG Q+V + + LV YL + L N K
Sbjct: 288 EAAAEYVRAQGYDPIILGDTITGEAQEVGIEQAALVR---NYLAKGL-------NTPKAI 337
Query: 273 ISGTDLKVLNEIKISNKKPLCLILGGEITVAVKG--TGKGGRNQQLALEFSKYLHKVKDQ 330
ISG GE TV + G G+GGR S+YL +
Sbjct: 338 ISG----------------------GECTVTIPGDIKGRGGR-------CSEYLLSLFAA 368
Query: 331 LNDF-DIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFK 389
D + L+A TDGIDG AGA + S GL DK+L+ +D Y FF
Sbjct: 369 SKDLPHLSALAADTDGIDGSEKNAGAWFDGVVRQSSQIAGLVPDKFLSLHDCYGFFAELA 428
Query: 390 NDHLHVFTGHTNTNVMD 406
V TG T TNV D
Sbjct: 429 ---ALVETGPTLTNVND 442
>UniRef50_A7DNA1 Cluster: Hydroxypyruvate reductase; n=1; Candidatus
Nitrosopumilus maritimus SCM1|Rep: Hydroxypyruvate
reductase - Candidatus Nitrosopumilus maritimus SCM1
Length = 425
Score = 126 bits (303), Expect = 1e-27
Identities = 83/246 (33%), Positives = 133/246 (54%), Gaps = 11/246 (4%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+R + I+ +K GII IP GS + K + + F PD ++ A ++ +
Sbjct: 71 MTRALNAIIP--VKSGIIVIPKGSKSII-KGKKFQIFNSRHPE-PDQTSVKAAKEVIKFV 126
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
D+L++ L+SGGGS+LL +P ITL++KI + K L SGA I+E N VRK +S +
Sbjct: 127 QNKKSDELIIFLVSGGGSSLLAMPNG-ITLDDKIFVTKLLLKSGASIQEFNCVRKHLSKI 185
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGG+L V+ +SLI+SD+ GD L IASG T + + A+++L+KY L P
Sbjct: 186 KGGKL-VENMKCDGISLIMSDVEGDDLSSIASGTTYMDNTTFSDALEILEKYKLKRKTPI 244
Query: 181 SVQTLLENNGDNLVFPTNNTS---NYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNV 237
V +LE ++ T S N +I +N+ KA ++ + Y V + +V G++
Sbjct: 245 EVLQILEKGVEDEKLETPKESKIENQVIANNENCLKAMEIEAKKKGY--KVKTLQVFGDI 302
Query: 238 QDVANK 243
++ K
Sbjct: 303 KEAVTK 308
Score = 81.0 bits (191), Expect = 5e-14
Identities = 86/306 (28%), Positives = 145/306 (47%), Gaps = 34/306 (11%)
Query: 116 VISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLI 175
+I + GG ++ A P + L D + L+ SG ++Q + K + +K L+
Sbjct: 135 IIFLVSGGGSSLLAMPNGIT---LDDKIFVTKLLLKSGASIQEFNCVRKHLSKIKGGKLV 191
Query: 176 DALPKSVQTLLENN--GDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNY-LPLVLSNK 232
+ + +L+ ++ GD+L + T+ + + S +++ +L P+ +
Sbjct: 192 ENMKCDGISLIMSDVEGDDLSSIASGTT--YMDNTTFSDALEILEKYKLKRKTPIEVLQI 249
Query: 233 VTGNVQDVANKYSKLVTVICKYLRQN------LEIDELKSN--IKKLEISGTDLKVLNEI 284
+ V+D + K + + + N +EI+ K +K L++ G + + +I
Sbjct: 250 LEKGVEDEKLETPKESKIENQVIANNENCLKAMEIEAKKKGYKVKTLQVFGDIKEAVTKI 309
Query: 285 --KISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAG 342
IS + +CLI+GGE TV V G G GGRNQ+L L K K K + I S G
Sbjct: 310 LENISEDQKMCLIVGGETTVKVLGKGMGGRNQELVLRILKNTQKFK------KLVIASMG 363
Query: 343 TDGIDGPTDAAGAIGYLNLISESTADGLDVDK-YLANNDTYNFFKLFKNDHLHVFTGHTN 401
TDGIDG + AGA I+E+ LD K +L N+D+ FF+ K + T T+
Sbjct: 364 TDGIDGNSVFAGA------ITENLKVDLDTMKEFLKNSDSGRFFQKQKGS---IVTDFTH 414
Query: 402 TNVMDI 407
TN+MDI
Sbjct: 415 TNLMDI 420
>UniRef50_A3V819 Cluster: MOFRL domain protein; n=2;
Rhodobacteraceae|Rep: MOFRL domain protein - Loktanella
vestfoldensis SKA53
Length = 407
Score = 122 bits (293), Expect = 2e-26
Identities = 80/198 (40%), Positives = 109/198 (55%), Gaps = 8/198 (4%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
+PD S AL + + +L LISGGGSALLP P +TL +KI + + L S
Sbjct: 97 VPDESGAKAALAVIAALRAAQGP--VLALISGGGSALLPAPAGALTLADKIAVNRLLLAS 154
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
G DI+ +N +R+ +SD+KGG A P V +LILSD+VGD L IASGPT A
Sbjct: 155 GLDIRAMNLIRQQLSDIKGGGFLRHAAPNNVTALILSDVVGDDLSAIASGPTAPPIGTAA 214
Query: 164 KAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELN 223
+AV +L+ NL D +P SV+ L P N +IGSN+ S AA+ Q +
Sbjct: 215 QAVTMLRDANLWDRVPPSVRDHLAQARPAPDLPA--ARNILIGSNRQSV-AAMAQAAGVA 271
Query: 224 YLPLVLSNKVTGNVQDVA 241
+ V++ VTG+V D A
Sbjct: 272 H---VIAAPVTGDVADAA 286
Score = 69.7 bits (163), Expect = 1e-10
Identities = 50/118 (42%), Positives = 65/118 (55%), Gaps = 11/118 (9%)
Query: 290 KPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGP 349
+P + GGE TV ++GTG+GGRNQ+LAL + V D L AG+DG DGP
Sbjct: 294 RPGITLWGGETTVMLQGTGRGGRNQELALRIA----IVAADRGWGDWTCLQAGSDGRDGP 349
Query: 350 TDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
TDAAG I + +S + LANND+Y L + D L + TG T TNV D+
Sbjct: 350 TDAAGGI----VDQDSLGKIAGLAALLANNDSY--AALAQVDGL-LLTGATGTNVADL 400
>UniRef50_Q30XP9 Cluster: Hydroxypyruvate reductase; n=3;
Desulfovibrio|Rep: Hydroxypyruvate reductase -
Desulfovibrio desulfuricans (strain G20)
Length = 486
Score = 121 bits (292), Expect = 3e-26
Identities = 75/260 (28%), Positives = 128/260 (49%), Gaps = 12/260 (4%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+ +E +L +I G + + G R + +E A +PD + + A ++ L
Sbjct: 105 MAAALEQLLGERITQGAVCVKYGHTVPL---RRITLYEAAHP-VPDAAGEAAARRMLELA 160
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
DL+L +++GG SAL P I L ++L GA I E+N +RK +S
Sbjct: 161 ASATGRDLVLCVLTGGASALTPALADGICLAHWQAATQRLLACGATIHEINAIRKHVSVF 220
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
GG+LA A PA +V+LI+SD+VGD LD+IASGPT ++ + +L +Y L ++P
Sbjct: 221 GGGRLAAAASPATLVALIISDVVGDDLDVIASGPTSPDSSTYEMCLGILDRYGLRHSMPA 280
Query: 181 SVQTLLENNGDNLVFPT--------NNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNK 232
++ LE V T + N ++ +N+ + +AA + Y P +L++
Sbjct: 281 AITRRLEEGAAGRVPETPAQGDAAFDRVHNVLVANNRQALEAAAQEAARQGYTPRILTST 340
Query: 233 VTGNVQDVANKYSKLVTVIC 252
+TG ++ A + +C
Sbjct: 341 MTGEAREKAKELVTAARQLC 360
Score = 87.8 bits (208), Expect = 5e-16
Identities = 52/117 (44%), Positives = 70/117 (59%), Gaps = 9/117 (7%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
P+CL+ GGE TV + G G GGRNQ++AL + +L + I +L AGTDG DGPT
Sbjct: 368 PVCLLAGGETTVTITGAGLGGRNQEMALAGAMHLQDCNN------ITMLCAGTDGSDGPT 421
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
DAAG ++ + GLD LA+N++Y F L K +L + TG T TNVMD+
Sbjct: 422 DAAGGFACAATLNAARCCGLDAGACLADNNSYVF--LEKTGNL-LKTGPTLTNVMDM 475
>UniRef50_Q44472 Cluster: Putative hydroxypyruvate reductase; n=71;
Proteobacteria|Rep: Putative hydroxypyruvate reductase -
Agrobacterium vitis (Rhizobium vitis)
Length = 438
Score = 119 bits (287), Expect = 1e-25
Identities = 74/207 (35%), Positives = 114/207 (55%), Gaps = 3/207 (1%)
Query: 34 VEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEK 93
+E E A +PD + A KI + L DDL++ LISGGGS+LL P +TL +K
Sbjct: 99 IEILE-ASHPVPDEMSIKAAEKIFAAVQGLGPDDLVVALISGGGSSLLVSPTGKMTLTDK 157
Query: 94 IGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASG 153
+ + L SGA I E+NTVRK +S +KGG LA A PA++V+LI+SD+ GD IASG
Sbjct: 158 RAVNQALLASGATISEMNTVRKHLSAIKGGHLARAALPAKLVTLIISDVPGDDPSEIASG 217
Query: 154 PTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTK 213
PTV + A ++ +Y ID LP+S + +L + ++ + I+ +
Sbjct: 218 PTVADPTTLADAAAIIARYG-ID-LPESARAVLVQGNETPKAGEVAGEIRLVAAPSIALE 275
Query: 214 AAVVQCIELNYLPLVLSNKVTGNVQDV 240
AA ++ PL+L + + G +++
Sbjct: 276 AAAAAALDAGLCPLILGDALEGEAREM 302
Score = 54.8 bits (126), Expect = 4e-06
Identities = 41/119 (34%), Positives = 59/119 (49%), Gaps = 11/119 (9%)
Query: 291 PLCLILGGEITVAVKGT--GKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDG 348
P ++ GGE TV++ G+GGRN + L + L I+ ++ TDGIDG
Sbjct: 323 PAVILSGGESTVSLGAMTEGRGGRNTEFLLSLAVALKGASG------IWAIAGDTDGIDG 376
Query: 349 PTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
DAAGA+ + + G+D L+ +D+Y FK + V TG T TNV DI
Sbjct: 377 VEDAAGALVAPDSLIRMRDAGIDPRATLSAHDSYTAFKAIGD---LVVTGPTLTNVNDI 432
>UniRef50_Q2Y6U9 Cluster: Hydroxypyruvate reductase precursor; n=2;
Betaproteobacteria|Rep: Hydroxypyruvate reductase
precursor - Nitrosospira multiformis (strain ATCC 25196
/ NCIMB 11849)
Length = 451
Score = 118 bits (284), Expect = 3e-25
Identities = 110/369 (29%), Positives = 172/369 (46%), Gaps = 39/369 (10%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
LPD S + A I I +L D LL L+SGGGS+LL +P + I+L + + +L S
Sbjct: 109 LPDESGEQGARAILAEIEKLGAGDFLLCLLSGGGSSLLSVPVTGISLNDLRDVTTQLLRS 168
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
GA I+E+NTVRK +S GG+LA ++ A V++LI+SD+ GD IASGP + +
Sbjct: 169 GAAIQEINTVRKHLSATAGGRLAALSR-APVLALIISDVTGDDPTHIASGPCAPDPTTFS 227
Query: 164 KAVDVLKKY--NLIDALPKSVQTLLENNGDNLVFP----TNNTSNYIIGSNKISTKAAVV 217
A+ +L+ Y N A+ ++++ +E P + N +I + S AA
Sbjct: 228 DALAILEHYKINASAAVTETLRAGVEGRLRETPKPGEAVFDQVENRVIATAHASLVAAAE 287
Query: 218 QCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTD 277
+VL + VTG ++VA ++ + + +Y R K + + G
Sbjct: 288 YFCAQGIPAVVLGDSVTGEAREVAKVFAAMAKEVRQYGR------PWKRPVALIS-GGET 340
Query: 278 LKVLNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIF 337
L E + KK G+GGRN L + L+ +I+
Sbjct: 341 TVTLRENEQGYKK----------------EGRGGRNTTFLLSLAIELNGAA------NIY 378
Query: 338 ILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFT 397
L+ TDGIDG + AGA+ + + +T ++ L N+ Y FF+ + V T
Sbjct: 379 ALACDTDGIDGTENNAGALITPDSLRRATDQRMNPSSLLTCNNAYAFFEALGD---LVTT 435
Query: 398 GHTNTNVMD 406
G T TNV D
Sbjct: 436 GPTRTNVND 444
>UniRef50_Q18JL1 Cluster: Probable hydroxypyruvate reductase;
probable glycerate kinase; n=1; Haloquadratum walsbyi
DSM 16790|Rep: Probable hydroxypyruvate reductase;
probable glycerate kinase - Haloquadratum walsbyi
(strain DSM 16790)
Length = 460
Score = 118 bits (284), Expect = 3e-25
Identities = 113/374 (30%), Positives = 171/374 (45%), Gaps = 54/374 (14%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
LP S A ++++ + L LV+I+GGGSALL P I + ++L
Sbjct: 121 LPSRSNITAAEQMRSYACDCGANTLSLVVITGGGSALLSAPAENIDKSALRRVTQELIQC 180
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
GA I +N VRK IS +KGGQLA PAQ V LI SD+ ++ASGP ++
Sbjct: 181 GAPIDRINAVRKHISTIKGGQLARALTPAQTVGLIFSDVTSGNPSVVASGPLSPDSTTYA 240
Query: 164 KAVDVLKKYNLIDALPKSVQTLLEN--NGDNLVFPTNNTSN-------YIIGSNKISTKA 214
A+ L++Y++ P+SV+ L+ NGD P+ +S+ ++ + A
Sbjct: 241 DALITLREYDV--NTPESVRMHLQRGANGDIDETPSELSSSTFDSPTTIVLADGMTALDA 298
Query: 215 AVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEIS 274
A C L Y PL+ ++ +++ A + +K I +E++ N ++
Sbjct: 299 AANACSNLGYEPLI----LSSSIRGEAREAAKTHVAIA---------EEVQRNRTPID-- 343
Query: 275 GTDLKVLNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDF 334
P ++ GGE TV V G G GG NQ+ AL + L
Sbjct: 344 ---------------PPAAILAGGETTVTVTGDGVGGPNQEFALAAALELPS-------- 380
Query: 335 DIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLH 394
+ + + TDG DGPTDAAGA ++++ A L ND Y+F L N L
Sbjct: 381 NTALCAIDTDGFDGPTDAAGATVTTATVNDNEASA--ARAALKANDAYSF--LDDNAALM 436
Query: 395 VFT-GHTNTNVMDI 407
+ T G T TNV D+
Sbjct: 437 LSTEGATGTNVNDL 450
>UniRef50_Q1ISV4 Cluster: Hydroxypyruvate reductase; n=1;
Acidobacteria bacterium Ellin345|Rep: Hydroxypyruvate
reductase - Acidobacteria bacterium (strain Ellin345)
Length = 448
Score = 114 bits (274), Expect = 5e-24
Identities = 64/180 (35%), Positives = 102/180 (56%), Gaps = 2/180 (1%)
Query: 9 LQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDL 68
L + + G+ I S D + Y+ G +S + +K+L T ++ L
Sbjct: 82 LMTHLGAGVTGIVACSTDPVTQVFGFRYYRGGHPMPNSDSVRAAEAILKSLSTHASRS-L 140
Query: 69 LLVLISGGGSALLPLP-KSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAV 127
++ L+SGG SA++ P ITLE+ I K L +SGA I+E+N VRK +S KGG+LA+
Sbjct: 141 VIFLVSGGASAIVEKPVDDSITLEDLIATYKVLVHSGAPIREINAVRKHLSATKGGRLAL 200
Query: 128 KAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLE 187
A PAQ VS+++SD+ +D +ASGPT+ +T + D++KK+ ++ P SV+ L E
Sbjct: 201 MASPAQQVSILVSDVPDGTVDSLASGPTMPDTTTVEECYDIVKKHKILKQFPASVRDLFE 260
Score = 80.2 bits (189), Expect = 9e-14
Identities = 58/150 (38%), Positives = 81/150 (54%), Gaps = 12/150 (8%)
Query: 259 LEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILGGEITVAVKG-TGKGGRNQQLA 317
+E+D + E + LK L ++ + +CLI GGE+TV V G G GGRNQQ A
Sbjct: 304 IEVDNTCDDWDYAEAADHLLKKLRTLRKGVSR-VCLISGGEVTVKVTGEAGVGGRNQQFA 362
Query: 318 LEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLA 377
L + K+ D+ DI +LSAGTDGIDG + AAGAI ++ ++A GLD L
Sbjct: 363 LYCAT---KIADE----DITVLSAGTDGIDGNSPAAGAIVDGTTLARASAVGLDAQTAL- 414
Query: 378 NNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
T+N + LF + TG T N+ D+
Sbjct: 415 --QTFNAYPLFDALGDAIVTGPTGNNIRDL 442
>UniRef50_A6LJ61 Cluster: Hydroxypyruvate reductase; n=1;
Thermosipho melanesiensis BI429|Rep: Hydroxypyruvate
reductase - Thermosipho melanesiensis BI429
Length = 403
Score = 114 bits (274), Expect = 5e-24
Identities = 74/248 (29%), Positives = 134/248 (54%), Gaps = 12/248 (4%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLI 60
M+ V N+L ++YGI+ G F + N + FE +NS + T + + +
Sbjct: 46 MAYAVSNVLD--VRYGIVITKYGHS--FGRIDNFDIFEAGHPIPDENSIKYTKIAL-DYF 100
Query: 61 TQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDL 120
++L K+D+LL+LISGGGS+L + +TLE + +L GA I E+N +RK +S +
Sbjct: 101 SKLKKNDILLLLISGGGSSLFEYLEDGVTLEFLKSITSELLKKGASIDEINILRKRLSKV 160
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPK 180
KGG+L Q A++++L+LSD++GD L+ IASGP + N+ ++KKY L L +
Sbjct: 161 KGGKLTRLIQ-AKIIALVLSDVLGDKLEYIASGPVYPDYTTFNQVKRIVKKYKL--KLGE 217
Query: 181 SVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDV 240
++ +L+ + V N +YI+G+ ++ K + + + +L+ ++ +D
Sbjct: 218 NIWNVLKKS----VKLEKNVPHYIVGNIDLACKKLKMVAEKYGFNTFLLTTRLNCEARDA 273
Query: 241 ANKYSKLV 248
+ +V
Sbjct: 274 GKFVASIV 281
Score = 88.2 bits (209), Expect = 4e-16
Identities = 50/118 (42%), Positives = 68/118 (57%), Gaps = 9/118 (7%)
Query: 290 KPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGP 349
KP C++ GGE V VKG G GGRNQ+L+ + + +++ + I S GTDG DGP
Sbjct: 289 KPYCVVFGGETVVKVKGNGMGGRNQELSFAAALEIEGIEN------VVIASVGTDGTDGP 342
Query: 350 TDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
TDAAG I N + G +++L NNDTYN K + + L + TG T TN+ DI
Sbjct: 343 TDAAGGIVDGNTVKILRERGYSPEEFLINNDTYNGLK--EAESL-LITGPTGTNLNDI 397
>UniRef50_Q9YDB7 Cluster: Glycerate kinase; n=1; Aeropyrum
pernix|Rep: Glycerate kinase - Aeropyrum pernix
Length = 448
Score = 113 bits (273), Expect = 6e-24
Identities = 78/240 (32%), Positives = 120/240 (50%), Gaps = 12/240 (5%)
Query: 16 GIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISG 75
G++ P G + +E EG+ LPD + ++ + D ++VL+SG
Sbjct: 73 GVVVKPRG---MTGNVEGLEVVEGSHP-LPDEWSLRAGRRLLEWAGSAGEGDNVVVLVSG 128
Query: 76 GGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVV 135
GGSAL +P + LE+ + L SGA I E+NTVRK +S +KGG+LA A PA+V+
Sbjct: 129 GGSALAEVPMEGLALEDLREVNMLLLKSGASIHEINTVRKHLSRIKGGRLAATAYPARVL 188
Query: 136 SLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVF 195
+ SD+ GD LD+IASGPTV + A+ VL++Y L D+ P V LLE V
Sbjct: 189 GVYASDVPGDRLDMIASGPTVPDPTTYGDALAVLERYGLRDSAPPRVVALLEAGARGEVE 248
Query: 196 PT--------NNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKL 247
T + T N + SN + + LVL++++ G ++V + +
Sbjct: 249 ETPKPGDRRLSTTENRLAASNMDVLEDLAAWLGGRGFNTLVLTSRLEGESREVGRALASI 308
Score = 69.7 bits (163), Expect = 1e-10
Identities = 47/119 (39%), Positives = 64/119 (53%), Gaps = 6/119 (5%)
Query: 289 KKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDG 348
K P L+ GGE TV V+G G+GGRN +LAL +S + + IL+ TDGIDG
Sbjct: 320 KPPAALLAGGETTVTVRGGGRGGRNMELALAWSLAMAYWSPEA---PAAILAMDTDGIDG 376
Query: 349 PTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
+DAAGA+ + L GLD + LA+ND+ F + V TG T TN+ +
Sbjct: 377 RSDAAGAVAWPWLPVALRDAGLDPYQLLADNDSERAFAYAGS---LVSTGLTGTNLNSV 432
>UniRef50_A6GR07 Cluster: Putative hydroxypyruvate reductase
oxidoreductase protein; n=1; Limnobacter sp. MED105|Rep:
Putative hydroxypyruvate reductase oxidoreductase
protein - Limnobacter sp. MED105
Length = 448
Score = 113 bits (272), Expect = 8e-24
Identities = 107/382 (28%), Positives = 174/382 (45%), Gaps = 35/382 (9%)
Query: 30 KSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPIT 89
K+ +E + A +PD Q A ++ I+++ D ++ L+SGGGS+LL +P I
Sbjct: 90 KTSTIEVVQAAHP-VPDEDGQRAARRLHKAISEVPSSDAVIALVSGGGSSLLSVPVRDIP 148
Query: 90 LEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDL 149
+ L + L GA I E+N VRK ++ GGQLA + A V L++SD+ GD
Sbjct: 149 FVDLQQLNRALLACGAPIDEMNIVRKHVTQTLGGQLAQICR-APVFQLLISDVPGDDPSS 207
Query: 150 IASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNK 209
IASGP + + A++V+K++ + +P S+ LE V T S+ + K
Sbjct: 208 IASGPFSPDESTFHDAMEVIKRWAV--QVPHSIARYLEKGVKGTVPDTPKRSSLVFRKVK 265
Query: 210 ISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIK 269
A+ ++ + N VT +++ K L + R ++ +
Sbjct: 266 THLLASNLKSL----------NAVTQHLEGKGYKVLNLGDTLEGEARDVAQVHAAIARQA 315
Query: 270 KLEISGTDLKVLNEIKISNKKPLCLILGGEITVAVKGT----GKGGRNQQLALEFSKYLH 325
+ G + PL +I GGE TV + T +GGRN + L + YL
Sbjct: 316 AMGQGGWP-----------EAPLAIISGGECTVTLNDTQLRQARGGRNSEFLLALAFYL- 363
Query: 326 KVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFF 385
+D ++ ++A TDGIDG AGA+ A L +L + +Y++F
Sbjct: 364 --RDLNAPVEVAAIAADTDGIDGIGGHAGALLLPGDRQLCKAAKLAPQLHLDQHTSYDYF 421
Query: 386 KLFKNDHLHVFTGHTNTNVMDI 407
K + D L + TG T TNV D+
Sbjct: 422 K--RLDRL-LMTGPTMTNVNDL 440
>UniRef50_Q97AL3 Cluster: Glycerate kinase; n=5;
Thermoplasmatales|Rep: Glycerate kinase - Thermoplasma
volcanium
Length = 420
Score = 107 bits (257), Expect = 5e-22
Identities = 85/287 (29%), Positives = 150/287 (52%), Gaps = 20/287 (6%)
Query: 66 DDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQL 125
+DL+LVLISGGGS+L +P+ IT+++ + + + + A+I ELNT+R +S +KGG+L
Sbjct: 125 NDLVLVLISGGGSSLFEIPQEGITIDQMASISRAMMDHSANIYELNTIRSALSSVKGGKL 184
Query: 126 AVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTL 185
A PA +++LI+SD+ GD + +IASGP +N + V KY D +P +
Sbjct: 185 ARILYPATIIALIISDVPGDDISIIASGPLAENKLDPSA---VYAKYR--DIIPIDITKY 239
Query: 186 LENNG-DNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLV-LSNKVTGNVQDVANK 243
+EN+ ++L F N N II +S + V + + P+V + + G+V +V+
Sbjct: 240 VENSSIEDLYF--RNVMNRII----LSNRDFVFEIYKRINEPIVSFGSNIQGDVTEVSEA 293
Query: 244 YSKLVTVICKYLRQNLEI---DELKSNIKKLEISGTDLKV-LNEIKISNKKP-LCLILGG 298
+ + + I K ++ E N+K I G +L++ L +K++N L L +G
Sbjct: 294 FVRSIYEISKIKGKSFWFVAGGETTVNVKGNGIGGRNLELALRFMKLANFSDFLFLSIGT 353
Query: 299 EITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDG 345
+ V G + + L+ S ++++ L+ D F L + G
Sbjct: 354 DGIDGVSPAAGGIVSSDMKLKISS--QELEETLDRNDAFTLLSAYHG 398
Score = 75.8 bits (178), Expect = 2e-12
Identities = 56/156 (35%), Positives = 74/156 (47%), Gaps = 14/156 (8%)
Query: 254 YLRQNLEIDELKSNIKK--LEISGTDLKVLNEIKISNKKPLCLILGGEITVAVKGTGKGG 311
Y R N I SNI+ E+S ++ + EI K + GGE TV VKG G GG
Sbjct: 269 YKRINEPIVSFGSNIQGDVTEVSEAFVRSIYEISKIKGKSFWFVAGGETTVNVKGNGIGG 328
Query: 312 RNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLD 371
RN +LAL F K N D LS GTDGIDG + AAG G ++ + +
Sbjct: 329 RNLELALRFMKLA-------NFSDFLFLSIGTDGIDGVSPAAG--GIVSSDMKLKISSQE 379
Query: 372 VDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
+++ L ND + + H + TG T NV DI
Sbjct: 380 LEETLDRNDAFTLLSAY---HGAIMTGRTGNNVSDI 412
>UniRef50_Q1J385 Cluster: Hydroxypyruvate reductase; n=4;
Deinococci|Rep: Hydroxypyruvate reductase - Deinococcus
geothermalis (strain DSM 11300)
Length = 422
Score = 106 bits (255), Expect = 9e-22
Identities = 80/238 (33%), Positives = 129/238 (54%), Gaps = 11/238 (4%)
Query: 16 GIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISG 75
G+ P G+ D+ + + E G+ +PD + A + + L + LLVL+SG
Sbjct: 66 GLAVPPRGTPDL-SAPQGAEVLPGSHP-VPDEHSVYAAEQALLRVRALPEGSQLLVLVSG 123
Query: 76 GGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVV 135
GGSALL P +TL +K L ++L +GA I+E+N VRK +S +KGG+LA +A A+V
Sbjct: 124 GGSALLSAPWG-VTLVQKQALTRELLRAGAAIEEINAVRKHLSRVKGGRLA-QATRARVR 181
Query: 136 SLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLEN-NGDNLV 194
+L++SD++GD +IASGPTV + A+ VL +Y + A P++ L G+
Sbjct: 182 ALLISDVIGDDPSVIASGPTVPDPTTFADALAVLDRYGV--AAPEARAHLEAGARGELAE 239
Query: 195 FP----TNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLV 248
P + N IIGSN++ +AA ++L++ G +D+A ++ LV
Sbjct: 240 TPKPGELPHVENVIIGSNRVLLEAAQAFLTAQGVRSVILADTFGGEARDLAGFHASLV 297
Score = 78.2 bits (184), Expect = 4e-13
Identities = 49/116 (42%), Positives = 67/116 (57%), Gaps = 10/116 (8%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
PL L+ GGE TV V+G G+GGRNQ+ AL + + L + ++ LSAG+DGIDG +
Sbjct: 310 PLVLLSGGEATVTVRGAGRGGRNQEFALW-------LLEDLGERGVYALSAGSDGIDGHS 362
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMD 406
DAAGA + + + A GLD +LA ND+ FF D L TG + N+ D
Sbjct: 363 DAAGAFLTPDSLVRARALGLDPRAFLARNDSGTFFAAL-GDAL--ITGPSGHNLND 415
>UniRef50_Q0FEP1 Cluster: MOFRL domain protein; n=1; alpha
proteobacterium HTCC2255|Rep: MOFRL domain protein -
alpha proteobacterium HTCC2255
Length = 429
Score = 106 bits (255), Expect = 9e-22
Identities = 62/177 (35%), Positives = 101/177 (57%), Gaps = 1/177 (0%)
Query: 39 GAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVK 98
GA +P A ++ + + + +D++++L+SGG SALLP P I+L++KI L +
Sbjct: 98 GASHPVPCKKGLMAANEVISRLEKATDNDVVIMLVSGGASALLPAPVKEISLDDKIRLNE 157
Query: 99 KLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQN 158
L + G DI ++N VRK +S LKGG + A PA+V S ILSD++GD L ++ SGP++ +
Sbjct: 158 ILLSCGFDIHQMNLVRKSVSRLKGGGVLNFAYPAKVKSYILSDVLGDDLSVVGSGPSIIS 217
Query: 159 TDGANKAVDVLKKYNLIDALPKSVQTLLEN-NGDNLVFPTNNTSNYIIGSNKISTKA 214
+ A +L ++ LP + LEN + +N + NT ++I N S A
Sbjct: 218 SGSIADARQLLINEGVLTQLPVKIIEYLENASNENEDNVSINTEAHLIAGNADSVAA 274
Score = 93.1 bits (221), Expect = 1e-17
Identities = 113/381 (29%), Positives = 177/381 (46%), Gaps = 47/381 (12%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
LP N A ++AL + N ++ ++ G S +P K + E I ++K ++
Sbjct: 71 LPKN-ANSSALAVTNFENMIDLKGCKVM----GASHPVPCKKGLMAANEVISRLEKATDN 125
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
D+ VI + GG A+ PA V + L D + L++ G + +
Sbjct: 126 --DV--------VIMLVSGGASALL--PAPVKEISLDDKIRLNEILLSCGFDIHQMNLVR 173
Query: 164 KAVDVLKKYNLID-ALPKSVQTLLENN--GDNLVFPTNNTSNYIIGSNKIS-TKAAVVQC 219
K+V LK +++ A P V++ + ++ GD+L + S II S I+ + ++
Sbjct: 174 KSVSRLKGGGVLNFAYPAKVKSYILSDVLGDDLSVVGSGPS--IISSGSIADARQLLINE 231
Query: 220 IELNYLPL----VLSNKVTGNVQDVA-NKYSKL-------VTVICKYLRQNLEIDELKSN 267
L LP+ L N N +V+ N + L V + K + + +D L +
Sbjct: 232 GVLTQLPVKIIEYLENASNENEDNVSINTEAHLIAGNADSVAAMAKEVGAQIILDPLIGD 291
Query: 268 IKKLEISGTDLKVLNEIKIS-NKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHK 326
+ + K+L EI+ S N KP + GGE TV +KGTGKGGRNQ+LAL F+
Sbjct: 292 VNQAVE-----KILFEIQSSKNDKPFAIAFGGETTVKLKGTGKGGRNQELALRFAVAAEN 346
Query: 327 VKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFK 386
V LN F LS GTDGIDGPTDAAG + + + + L NND+Y K
Sbjct: 347 V--FLNRPWCF-LSGGTDGIDGPTDAAGGLVDNGTLFRIKNKNKSIYELLENNDSYQALK 403
Query: 387 LFKNDHLHVFTGHTNTNVMDI 407
+ ++ + G T TNV D+
Sbjct: 404 MAED---LILIGATGTNVADL 421
>UniRef50_A6X7S4 Cluster: Hydroxypyruvate reductase; n=1;
Ochrobactrum anthropi ATCC 49188|Rep: Hydroxypyruvate
reductase - Ochrobactrum anthropi (strain ATCC 49188 /
DSM 6882 / NCTC 12168)
Length = 472
Score = 103 bits (246), Expect = 1e-20
Identities = 106/421 (25%), Positives = 190/421 (45%), Gaps = 52/421 (12%)
Query: 1 MSREVENILQSKIKYGIISIPMGS-LDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNL 59
M+ V+++L ++ GI + + D FNK+ E + G LP+ + + K+ +
Sbjct: 80 MAMAVDHVLGDRLTRGIAIVKIHEETDRFNKT---EVYVGGHP-LPNEAGYRASRKMIEI 135
Query: 60 ITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISD 119
I Q DDL + +ISGG SAL+ P I+L+++I L SGA I E+N VR+ IS
Sbjct: 136 IDQAGPDDLFIGVISGGSSALMSCPIDGISLQDEIDTTDVLLKSGAGIYEINAVRRHISA 195
Query: 120 LKGGQLAVKAQP--AQVVSLILSDIVGDPL--DLIA------SGPTVQNTDGANKAVDVL 169
L GG LA + Q A+++ +SD VG P D+ S P + + A +
Sbjct: 196 LNGGMLAKRIQDVGAELIGFGISDAVGSPATGDIAVPYAAYKSTPIGPDATTLDDARATI 255
Query: 170 KKYNLIDALPKSVQTLLENNGDNLVFPT--NNTSNYIIGSNKISTKAAVVQCIELNYLPL 227
Y++ D LPKSV L N G + P N + +++ + S A C E+ +
Sbjct: 256 VNYDVADRLPKSVVDYLMNAGPDKETPKAFPNNTYFLLNTLPDSCIYAREICEEMGIPAI 315
Query: 228 VLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKIS 287
++S+ + G +D ++ + ++++ G +K + +S
Sbjct: 316 IISSFLEGESKDAGTFFASMA--------------------REIQTYGNPVKA-PCVLLS 354
Query: 288 NKKPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGID 347
+ + IL + ++G GG Q++ + F+ K K +LS ++G D
Sbjct: 355 SGEVTTQILDNSV---IRG--HGGPGQEMTISFAITAAKTKGAC------LLSIDSEGTD 403
Query: 348 GPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
G AG I ++ + G+++ + L + + + VFTG+T TN+ D+
Sbjct: 404 GTAKVAGGITDSASLAAAAGKGINLHQTLREHSCFEALDAIGS---AVFTGNTGTNLCDL 460
Query: 408 H 408
+
Sbjct: 461 N 461
>UniRef50_A0RVR5 Cluster: Hydroxypyruvate reductase; n=1;
Cenarchaeum symbiosum|Rep: Hydroxypyruvate reductase -
Cenarchaeum symbiosum
Length = 419
Score = 102 bits (244), Expect = 2e-20
Identities = 65/201 (32%), Positives = 107/201 (53%), Gaps = 7/201 (3%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
+P + A ++ ++ + + +L L+SGG S+LL +P I+L++K + + S
Sbjct: 89 VPGQDSVAAARAVQKILHRRRGSEFVLFLVSGGSSSLLCMPDG-ISLDDKAYTSELMLKS 147
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
GA I+E N VRK +S +KGG+L V P +L++SD+VGD L IASG T + +
Sbjct: 148 GATIQEFNCVRKHLSQVKGGRL-VAGLPCDAAALVMSDVVGDDLSSIASGTTYCDATTYS 206
Query: 164 KAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNT---SNYIIGSNKISTKAAVVQCI 220
A+D+++ L D +P + LE + T N++I +N+ T A +
Sbjct: 207 NALDIVRGLGLADRMPPAALARLEAGARGGIPETPKEPMFPNWVIAANRDCTAAMGSRAR 266
Query: 221 ELNYLPLVLSNKVTGNVQDVA 241
E Y P +LS V+G+V D A
Sbjct: 267 EFGYEPEILS--VSGDVSDAA 285
Score = 82.6 bits (195), Expect = 2e-14
Identities = 54/117 (46%), Positives = 67/117 (57%), Gaps = 16/117 (13%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
P C+I GGE TV VKG G+GGRNQ+L L + L ++K + S GTDGIDG T
Sbjct: 296 PPCVIFGGETTVRVKGDGRGGRNQELVL---RLLRELKGE----SFVAASIGTDGIDGNT 348
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
+ AGA IS A D+D YLA ND+ +FF V TG+T TN+MDI
Sbjct: 349 EDAGA------ISGGDAGIDDIDAYLAENDSGSFFAKHGG---QVKTGYTRTNLMDI 396
>UniRef50_Q6W213 Cluster: Glycerate dehydrogenase / Hydroxypyruvate
reductase; n=1; Rhizobium sp. NGR234|Rep: Glycerate
dehydrogenase / Hydroxypyruvate reductase - Rhizobium
sp. (strain NGR234)
Length = 424
Score = 101 bits (241), Expect = 5e-20
Identities = 66/217 (30%), Positives = 105/217 (48%), Gaps = 5/217 (2%)
Query: 22 MGSLDVFNKSRNVEYFEGAKD---NLP--DNSAQNTALKIKNLITQLNKDDLLLVLISGG 76
+G V N+ EGA+ P D A +++ ++ D++LVL+S G
Sbjct: 76 IGKAVVVTDHENLRPVEGARTLCAGYPAIDPGGMLAASEVELAVSAATPKDMVLVLVSAG 135
Query: 77 GSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVS 136
G A+L P I+L KI L L GAD+KE+ VR +S + G+LA KA AQV+S
Sbjct: 136 GPAMLCAPPFGISLGAKIRLQDMLVREGADMKEILAVRHAVSRINDGRLAEKAGGAQVLS 195
Query: 137 LILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFP 196
+I SD+ GD + + GPT + A+ VL+KY L+ +++ + +
Sbjct: 196 MIYSDVSGDEIIAVTQGPTARLFQRNATAIGVLEKYGLVGRTDRAILDYIRCAHEGRAHA 255
Query: 197 TNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKV 233
+ N IIG N +S AA + + L+ ++V
Sbjct: 256 GGSIENLIIGGNGVSLNAAAAHAAKCHGPALMGQHRV 292
Score = 35.5 bits (78), Expect = 2.6
Identities = 34/110 (30%), Positives = 49/110 (44%), Gaps = 6/110 (5%)
Query: 298 GEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIG 357
G + + +GGRN ++AL F+ L ++ L +F LS TDG GP + GAI
Sbjct: 315 GPLALVSGRVARGGRNHEIALRFA--LLAEREPLARPWVF-LSGNTDGRHGPHRSVGAIV 371
Query: 358 YLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
S G+D + L D + D L + G T +NV DI
Sbjct: 372 DRGSCSWMRQLGIDPRRQLTAGDASSVLAT-SGDLLLI--GDTASNVTDI 418
>UniRef50_A7H7H1 Cluster: MOFRL domain protein; n=2;
Anaeromyxobacter|Rep: MOFRL domain protein -
Anaeromyxobacter sp. Fw109-5
Length = 456
Score = 97.5 bits (232), Expect = 6e-19
Identities = 54/118 (45%), Positives = 72/118 (61%)
Query: 70 LVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKA 129
LVL+SGGGSAL P + ++LEEK + + +GA I+ELN VRK +SDLKGG+L +
Sbjct: 149 LVLLSGGGSALAVAPAAGLSLEEKADALAAVMRAGATIQELNAVRKHLSDLKGGRLGARL 208
Query: 130 QPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLE 187
PA V L+LSD+ GD L IASGP V + VL + ALP +V+ +E
Sbjct: 209 APAPVRVLVLSDVPGDDLSTIASGPLVPDPTTWADVGAVLDRTRTRGALPAAVRAFVE 266
Score = 48.4 bits (110), Expect = 4e-04
Identities = 35/93 (37%), Positives = 48/93 (51%), Gaps = 9/93 (9%)
Query: 287 SNKKPLCLILGGEITVAVKGTGK--GGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTD 344
+ + P L LGGE T++V GGR Q LAL +K +L L+AG+D
Sbjct: 338 AGRGPRLLALGGEPTISVPAAAHPDGGRAQALALLAAK-------ELAGLPAAALAAGSD 390
Query: 345 GIDGPTDAAGAIGYLNLISESTADGLDVDKYLA 377
G DGPT+ AGA+ + A G+D+D LA
Sbjct: 391 GRDGPTEHAGAVVDGETAPGAAAAGVDLDAALA 423
>UniRef50_Q2S2B0 Cluster: Hydroxypyruvate reductase; n=1;
Salinibacter ruber DSM 13855|Rep: Hydroxypyruvate
reductase - Salinibacter ruber (strain DSM 13855)
Length = 472
Score = 97.1 bits (231), Expect = 8e-19
Identities = 70/209 (33%), Positives = 102/209 (48%), Gaps = 8/209 (3%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
LP + A +I D+LLLVL+SGGG+AL LP + L + L S
Sbjct: 132 LPTEAGVRGARRIVEQAEAAGADELLLVLVSGGGTALGTLPADGMALADLKRTYHLLLRS 191
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
G +I+++N VRK ++ GGQLA A PA V SLI+SD+VG+ + +IASGPTV +
Sbjct: 192 GVNIQQMNAVRKHLTQTGGGQLARAAAPADVGSLIVSDVVGNDMSVIASGPTVPDPTTYE 251
Query: 164 KAVDVLKKYNLIDALPKSVQTLLEN--NGDNLVFP------TNNTSNYIIGSNKISTKAA 215
A+ VL +L + V+T L G P TSN ++G+N+ + AA
Sbjct: 252 DAMRVLYTRDLWTEVSGPVRTRLSTGARGRRPETPGPEADCFERTSNTLVGTNRTALAAA 311
Query: 216 VVQCIELNYLPLVLSNKVTGNVQDVANKY 244
Y + +V G + V +
Sbjct: 312 REAAEARGYAVRQEAEEVEGEARSVGKAH 340
Score = 89.0 bits (211), Expect = 2e-16
Identities = 53/118 (44%), Positives = 65/118 (55%), Gaps = 8/118 (6%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
P C + GGE TV V G GKGGRNQ++AL + + +LS GTDGIDGPT
Sbjct: 352 PTCWLWGGETTVTVTGDGKGGRNQEVALGAALAMEDASRPT-----VLLSGGTDGIDGPT 406
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDIH 408
DAAGA ++ A D +L ND Y FF DHL + G T+TNVMD+H
Sbjct: 407 DAAGAWATPMTTEKARAVDCDPKDHLRQNDAYPFFDAI--DHL-LRPGPTHTNVMDVH 461
>UniRef50_Q15Z21 Cluster: Hydroxypyruvate reductase; n=2;
Alteromonadales|Rep: Hydroxypyruvate reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 412
Score = 95.9 bits (228), Expect = 2e-18
Identities = 64/204 (31%), Positives = 112/204 (54%), Gaps = 8/204 (3%)
Query: 45 PDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSG 104
PDN++ + +L+ + +L LISGGGS+L+ LP + +K L + L SG
Sbjct: 90 PDNNSLVAGKALLDLVRETPATTPILFLISGGGSSLMCLPVDDVPFADKQQLNQFLLRSG 149
Query: 105 ADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANK 164
A I E+NTVRK +S +KGG+LA +A ++ V+L++SD+VGD IASGPT+ + +
Sbjct: 150 ASIDEINTVRKQLSLVKGGRLA-QAAKSKHVTLMISDVVGDNAADIASGPTISDPSTKAQ 208
Query: 165 AVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSN--YIIGSNKISTKAAVVQCIEL 222
A +L+KY+ V ++ V P ++ + +I+ + + + AA+ +
Sbjct: 209 AAAILQKYHW-----TPVGSIANYLAKPEVAPKHSAPSEYHIVANAQHAIDAAIAVAQQQ 263
Query: 223 NYLPLVLSNKVTGNVQDVANKYSK 246
+ VL ++ G +DVA +++
Sbjct: 264 GWQTKVLGYEIQGEARDVAKAHAQ 287
Score = 60.5 bits (140), Expect = 8e-08
Identities = 42/121 (34%), Positives = 65/121 (53%), Gaps = 10/121 (8%)
Query: 287 SNKKPLCLILGGEITVAV-KGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDG 345
+N + + L GGE+TV V K G GG NQ+ + + L ++ I ++ TDG
Sbjct: 294 ANGERVMLFSGGELTVTVGKEYGDGGPNQEYLMALALELDGIEG------ISAMACDTDG 347
Query: 346 IDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVM 405
+DG D AGA + ++ + A G+ + LA+++++ FF D L V TG TNTNV
Sbjct: 348 VDGSKDVAGAYIDSSTLNRAAAAGVSAAELLASHNSHKFFGAI--DDL-VITGPTNTNVN 404
Query: 406 D 406
D
Sbjct: 405 D 405
>UniRef50_Q3IT62 Cluster: Probable hydroxypyruvate reductase;
probable glycerate kinase; n=1; Natronomonas pharaonis
DSM 2160|Rep: Probable hydroxypyruvate reductase;
probable glycerate kinase - Natronomonas pharaonis
(strain DSM 2160 / ATCC 35678)
Length = 426
Score = 95.5 bits (227), Expect = 2e-18
Identities = 61/182 (33%), Positives = 96/182 (52%), Gaps = 5/182 (2%)
Query: 68 LLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAV 127
L+L ++GGGSALL P ++ + + + L ++GA + ELN VR+V S++KGG LA
Sbjct: 132 LVLAPMTGGGSALLCAPADGLSAADIRTVTEALLDAGASVDELNAVRRVCSEIKGGGLAA 191
Query: 128 KAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLE 187
A PA VV +++SD+VGD ++ASGPTV + A VL +Y +DA P + L
Sbjct: 192 AAAPATVVGVVMSDVVGDDPAVVASGPTVPVEAAPDVAATVLDRYG-VDA-PAVRRWLSS 249
Query: 188 NNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKL 247
++ P+ N++I S + AA Y VLS + G + ++ +
Sbjct: 250 ATPES---PSVAARNHVIASGWDAVDAARAHAAAAGYQTCVLSTHLEGEAEQSGRFHAAV 306
Query: 248 VT 249
T
Sbjct: 307 AT 308
Score = 54.4 bits (125), Expect = 5e-06
Identities = 41/117 (35%), Positives = 57/117 (48%), Gaps = 16/117 (13%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
P ++ GGE TV+V G G GG N + AL + K+ D + + + TDG DG T
Sbjct: 320 PAVILSGGETTVSVSGDGVGGPNMEFALAAAP---KLPD-----EAVVGAVDTDGSDGST 371
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
DAAGA L+ T D L ND+Y + + +F+G T TNV D+
Sbjct: 372 DAAGA-----LVDADTVDPQVARTALDENDSY---RALADAGALLFSGSTGTNVNDL 420
>UniRef50_Q89CG7 Cluster: Hydroxypyruvate reductase; n=14;
Alphaproteobacteria|Rep: Hydroxypyruvate reductase -
Bradyrhizobium japonicum
Length = 427
Score = 93.9 bits (223), Expect = 7e-18
Identities = 70/209 (33%), Positives = 104/209 (49%), Gaps = 7/209 (3%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
+PD + A L + DDLLLVL++GGGSA P I+ +K + K L S
Sbjct: 94 VPDEAGLKGAADTLALAGEAGPDDLLLVLLTGGGSANWIAPVDGISFAQKQAVNKALLRS 153
Query: 104 GADIKELNTVRKVISDLKGGQLA-VKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGA 162
GA I E+N VRK +S +KGG+LA A++V+L +SD+ D IASGPTV +
Sbjct: 154 GAPIGEMNVVRKHLSRIKGGRLARAGRNAAEIVTLAISDVPHDDPSAIASGPTVPDPTTL 213
Query: 163 NKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTN----NTSNYIIGSNKISTKAAVVQ 218
A ++ +Y L + +V+ L+N + P + S +I K S AAV
Sbjct: 214 ADARAIVARYKL--DIDHAVRRALDNPDNESCKPDDAAFARASFELIARPKQSLDAAVKL 271
Query: 219 CIELNYLPLVLSNKVTGNVQDVANKYSKL 247
E Y + L + G ++VA ++ L
Sbjct: 272 AKEAGYETIDLGADLEGEAREVAAHHAGL 300
Score = 64.5 bits (150), Expect = 5e-09
Identities = 49/122 (40%), Positives = 62/122 (50%), Gaps = 13/122 (10%)
Query: 290 KPLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDG- 348
K + ++ GGE+TV V+G G+GG NQ+ AL + L KD I L+ TDG DG
Sbjct: 309 KRIAILSGGELTVTVRGQGRGGPNQEYALALAGLL---KDTAG---ISALAGDTDGADGG 362
Query: 349 ---PTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVM 405
PTD AGA+ ++ A L YL NND FF+ D L G T TNV
Sbjct: 363 AGHPTDPAGALIDAATFAKMKALALQPQAYLDNNDATTFFEA-TGDLL--MPGPTLTNVN 419
Query: 406 DI 407
DI
Sbjct: 420 DI 421
>UniRef50_A6GGC1 Cluster: Probable hydroxypyruvate reductase ;
probable glycerate kinase; n=1; Plesiocystis pacifica
SIR-1|Rep: Probable hydroxypyruvate reductase ; probable
glycerate kinase - Plesiocystis pacifica SIR-1
Length = 500
Score = 77.4 bits (182), Expect = 7e-13
Identities = 52/135 (38%), Positives = 72/135 (53%), Gaps = 4/135 (2%)
Query: 44 LPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANS 103
LP + +++ L Q+ DL+L ISGG SALL P P EE +V +
Sbjct: 152 LPGPKSAAACARLRELARQVQPRDLVLCPISGGSSALLSDPVLPA--EEWSAMVAHFLSR 209
Query: 104 GADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGAN 163
I +N +R+ LK G LA PA VVSLI+SD++GD L LI SGPT+ D
Sbjct: 210 DVPIHPINWLRRRCDALKAGGLARLFAPAAVVSLIISDVIGDELALIGSGPTIY-PDKRE 268
Query: 164 KAVDVLKKYNLIDAL 178
+D +++ +L DAL
Sbjct: 269 PELDTIRR-DLGDAL 282
Score = 72.5 bits (170), Expect = 2e-11
Identities = 47/124 (37%), Positives = 73/124 (58%), Gaps = 9/124 (7%)
Query: 289 KKPLCLILGGEITVAVK--GTGKGGRNQQLALEFSKYLHKVK---DQLNDFDIFILSAGT 343
+ P C++ GGE TV ++ +G GGRNQ+LAL + L ++ D+ + + +L+ T
Sbjct: 374 RSPACIVTGGETTVNLELGASGAGGRNQELALAAAAPLATLRAGRDRPRERAV-LLTLAT 432
Query: 344 DGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTN 403
DG DGPTDAAGA+ + + + ADGLD ++ L +D++ + D L TG T TN
Sbjct: 433 DGEDGPTDAAGALVDPSTEARAQADGLDPEQALRAHDSHTLLARLE-DTLR--TGPTGTN 489
Query: 404 VMDI 407
V D+
Sbjct: 490 VCDL 493
>UniRef50_Q4JCE1 Cluster: MOFRL family protein; n=4;
Sulfolobaceae|Rep: MOFRL family protein - Sulfolobus
acidocaldarius
Length = 393
Score = 76.2 bits (179), Expect = 2e-12
Identities = 43/108 (39%), Positives = 63/108 (58%), Gaps = 3/108 (2%)
Query: 67 DLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLA 126
D+++ L+SGG SAL+ P+ + ++I KL SG I E+NTVRK +S +KGG LA
Sbjct: 111 DIVIFLLSGGASALVEYSDVPLEVLKEIN--DKLVTSGLSIDEINTVRKHLSKIKGGWLA 168
Query: 127 VKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNL 174
K A +VSLI+SD+ + + SGPT+ + A +L K L
Sbjct: 169 -KYSKAPIVSLIISDVPSSDISFVGSGPTILDKTSVIDAERILAKIGL 215
Score = 45.2 bits (102), Expect = 0.003
Identities = 35/130 (26%), Positives = 59/130 (45%), Gaps = 15/130 (11%)
Query: 280 VLNEIKISNKKPLCLILGGEITVAVKG-TGKGGRNQQLALEFSKYLHKVKDQLNDFDIFI 338
+ N N++ ++ GGE V + GKGGRN ++ L F KY+ + +
Sbjct: 275 IANTFARINRQENVILAGGEPDVKITSKAGKGGRNGEVCLGFLKYIRA--------NAKL 326
Query: 339 LSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTG 398
+ TDGIDG ++ AG N+ E ++D Y+ ++ +Y + N FTG
Sbjct: 327 YAVATDGIDGNSEYAGCYVDHNVKIE------NIDYYVESHSSYEILEKTGNVIQTGFTG 380
Query: 399 HTNTNVMDIH 408
N+ +H
Sbjct: 381 DNVNNIYVLH 390
>UniRef50_Q5JEQ8 Cluster: Glycerate kinase-related protein,
containing MOFRL domain; n=4; Thermococcaceae|Rep:
Glycerate kinase-related protein, containing MOFRL
domain - Pyrococcus kodakaraensis (Thermococcus
kodakaraensis)
Length = 248
Score = 73.3 bits (172), Expect = 1e-11
Identities = 59/200 (29%), Positives = 101/200 (50%), Gaps = 24/200 (12%)
Query: 223 NYLPLVLSNKVTGNV-QDVANKYSKLVT---VICKYLRQNLEIDELKSNIKKLEISGTDL 278
+Y+ L L K + +D+ N ++ L+ ++C+ ++ + L+++I + G
Sbjct: 52 HYIELGLEGKAEETLKEDLPNVHNFLIASNVLVCEAAQRKAKELGLEAHILTTTLEGEAR 111
Query: 279 KV-------LNEIKISN---KKPLCLILGGEITVAVKG-TGKGGRNQQLALEFSKYLHKV 327
+V + EI N K+P LI GGE TV ++G G GG NQ+ AL ++ + +
Sbjct: 112 EVALAFGSVIEEIYHRNRPFKRPCVLIAGGETTVTIEGKAGLGGPNQEFALSIARKISGL 171
Query: 328 KDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKL 387
+ + +L+ TDG DGPTDAAG + + +G+D+++YL +++ Y K
Sbjct: 172 RG------VAVLAMDTDGTDGPTDAAGGLVDSHTAEVLRNEGIDLEEYLRSHNAYEALKK 225
Query: 388 FKNDHLHVFTGHTNTNVMDI 407
K V TG T TNV I
Sbjct: 226 AK---ALVVTGPTRTNVNSI 242
Score = 34.7 bits (76), Expect = 4.6
Identities = 24/89 (26%), Positives = 43/89 (48%), Gaps = 5/89 (5%)
Query: 168 VLKKYNLIDALPKSVQTLLE-----NNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIEL 222
+LK Y L + LP+SV+ +E + L N N++I SN + +AA + EL
Sbjct: 36 ILKLYGLWEKLPESVRHYIELGLEGKAEETLKEDLPNVHNFLIASNVLVCEAAQRKAKEL 95
Query: 223 NYLPLVLSNKVTGNVQDVANKYSKLVTVI 251
+L+ + G ++VA + ++ I
Sbjct: 96 GLEAHILTTTLEGEAREVALAFGSVIEEI 124
>UniRef50_A3ESH2 Cluster: Putative glycerate kinase; n=1;
Leptospirillum sp. Group II UBA|Rep: Putative glycerate
kinase - Leptospirillum sp. Group II UBA
Length = 431
Score = 72.9 bits (171), Expect = 1e-11
Identities = 49/171 (28%), Positives = 83/171 (48%)
Query: 45 PDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSG 104
P + N A + + + +LL +SGG S+LL P I+L +K L+ L G
Sbjct: 98 PGEDSLNAAEAALDFVGNIPPGGVLLFALSGGTSSLLCKPARGISLAQKKNLIGLLMRKG 157
Query: 105 ADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANK 164
A I LNTVR +S +KGG+L + V +++LSD+ ++ SGPTV K
Sbjct: 158 APIHILNTVRTHLSLIKGGELLRNFRGQHVHTVLLSDVPCQSAGIVGSGPTVFCQRDGKK 217
Query: 165 AVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAA 215
+ +L+++ + +P V+ LE P + +++G + + K A
Sbjct: 218 TLSILEEWLDPEDIPDCVRQHLETLPPLSPPPLSREPLHVLGDSGVVLKKA 268
>UniRef50_A3JCN1 Cluster: Hydroxypyruvate reductase; n=1;
Marinobacter sp. ELB17|Rep: Hydroxypyruvate reductase -
Marinobacter sp. ELB17
Length = 197
Score = 70.1 bits (164), Expect = 1e-10
Identities = 53/145 (36%), Positives = 72/145 (49%), Gaps = 11/145 (7%)
Query: 262 DELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFS 321
D+L+ +LE L + + +IS +PL ++ GGE +V V+G+G+GGRN L
Sbjct: 53 DDLEEEACELERGHALLAIAAQNEIS--RPLLILSGGETSVMVRGSGRGGRNVDYLLGLF 110
Query: 322 KYLHKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDT 381
L I L+ TDGID D AGA+ + + G D YLANND
Sbjct: 111 STLAGAP------GIHALAIDTDGIDRSEDNAGALFGPDDWARMQMQGFDPSTYLANNDA 164
Query: 382 YNFFKLFKNDHLHVFTGHTNTNVMD 406
Y+FF D L + TG T TNV D
Sbjct: 165 YSFFAAL--DGL-IVTGPTCTNVND 186
>UniRef50_Q703V9 Cluster: Glycerate kinase; n=1; Thermoproteus
tenax|Rep: Glycerate kinase - Thermoproteus tenax
Length = 398
Score = 70.1 bits (164), Expect = 1e-10
Identities = 44/145 (30%), Positives = 79/145 (54%), Gaps = 4/145 (2%)
Query: 45 PDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSG 104
P + + + + ++ L++ + ++ L+SGG S+L +P P ++ + L SG
Sbjct: 75 PSHRSFKAGEAVLDYVSSLSRGERVVFLVSGGASSLAEVPLIPE--DDFLITWGLLLRSG 132
Query: 105 ADIKELNTVRKVISDLKGGQLAVKA--QPAQVVSLILSDIVGDPLDLIASGPTVQNTDGA 162
DI ++N +RK IS +KGG+L A + A V +LI SD+ D + SGP V ++ A
Sbjct: 133 LDIHQMNAIRKRISAIKGGKLGAMAVARGAYVYNLIASDVPCDDPSDVGSGPAVPDSSTA 192
Query: 163 NKAVDVLKKYNLIDALPKSVQTLLE 187
+A+ LK L + +P + +T +E
Sbjct: 193 EEALTSLKIAGLWERMPITARTAIE 217
Score = 54.0 bits (124), Expect = 7e-06
Identities = 40/111 (36%), Positives = 55/111 (49%), Gaps = 13/111 (11%)
Query: 294 LILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAA 353
L+LGGE TV V+G G+GGR + AL F + + +F ++ TDG+DG T A
Sbjct: 281 LLLGGEPTVTVRGGGRGGRTTEFALSFILASRR-------YAVFAMA--TDGLDGNTGVA 331
Query: 354 GAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNV 404
G L+ E G DV Y A N+T + F V TG T +N+
Sbjct: 332 GVWADPGLLGELVKRG-DVSSYFAENNT---LEPFAETGRVVRTGPTGSNL 378
>UniRef50_A7BX18 Cluster: Hydroxypyruvate reductase; n=1; Beggiatoa
sp. PS|Rep: Hydroxypyruvate reductase - Beggiatoa sp. PS
Length = 423
Score = 68.5 bits (160), Expect = 3e-10
Identities = 47/154 (30%), Positives = 77/154 (50%), Gaps = 2/154 (1%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLD-VFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNL 59
M+ +L ++I ++ G L+ F + + E A +PD S+ + +
Sbjct: 52 MATGAYEVLGNQITQALVITKFGHLEKTFQPAYPMICLEAAHP-VPDESSLVAGQTLLDF 110
Query: 60 ITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISD 119
I +L +L L SGG SAL+ + ITL + + L SG I +N +RK +S
Sbjct: 111 IHKLPPQLPVLTLTSGGASALVEVLVPGITLSNLQNVNQWLLGSGLPIHAMNQIRKSLSA 170
Query: 120 LKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASG 153
+KGG LA + V++L++SD+ GD L +I SG
Sbjct: 171 IKGGHLATHLKNHPVLNLVISDVPGDDLQIIGSG 204
Score = 48.4 bits (110), Expect = 4e-04
Identities = 43/118 (36%), Positives = 56/118 (47%), Gaps = 10/118 (8%)
Query: 291 PLCLILGGEITVAV-KGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGP 349
P I E TV + + G+GGR Q LAL + L ++F+L+ GTDG DGP
Sbjct: 308 PGIYIWSSETTVHLPEKPGQGGRCQHLALSAACEL------AGRNNVFLLAMGTDGNDGP 361
Query: 350 TDAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
D AGA+ + L + LA D F L + L + TG T TNVMDI
Sbjct: 362 CDVAGALVDGKTLERGNQKRLHAIQCLATADAGRF--LTASGDL-MDTGPTGTNVMDI 416
>UniRef50_A6VRW1 Cluster: MOFRL domain protein; n=2;
Proteobacteria|Rep: MOFRL domain protein - Marinomonas
sp. MWYL1
Length = 376
Score = 66.9 bits (156), Expect = 9e-10
Identities = 54/136 (39%), Positives = 74/136 (54%), Gaps = 19/136 (13%)
Query: 277 DLKVLNEI---KISNKKPLCLILGGEITVAV-KGTGKGGRNQQLALEFSKYLHKVKDQLN 332
D++VL+ ++ N +P I GGE TV + + G GGRNQ LAL ++ + +
Sbjct: 249 DVEVLSSYIGQQLINAEPGVYIFGGEPTVKLPENPGNGGRNQALALGIAENI------VG 302
Query: 333 DFDIFILSAGTDGIDGPTDAAGAIGYLNLISESTADGLD-VDKYLANNDTYNFFKLFKND 391
+I +L AGTDG DGPTDAAG I + STA L V L D + + + D
Sbjct: 303 RDNILVLVAGTDGSDGPTDAAGGI-----VDGSTAKDLHAVRDALKRADAGTYLR--EQD 355
Query: 392 HLHVFTGHTNTNVMDI 407
+ + TG TNTNVMDI
Sbjct: 356 AIFI-TGPTNTNVMDI 370
Score = 63.7 bits (148), Expect = 9e-09
Identities = 38/123 (30%), Positives = 64/123 (52%), Gaps = 1/123 (0%)
Query: 31 SRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITL 90
+ NV E A +PD ++ N ++ + + LL+L+SGG SAL + ++L
Sbjct: 81 ANNVTVIESAHP-VPDQNSLNAGKQMLATVNSMEAGSKLLLLVSGGASALSEALPADVSL 139
Query: 91 EEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLI 150
E+ L ++ +G +I ++NT RK S +K G+L V L +SD+ GD + +I
Sbjct: 140 EDWQKLTNQMLAAGYNIDQINTRRKETSLIKDGKLLENFTGTDVRVLAISDVEGDDISVI 199
Query: 151 ASG 153
SG
Sbjct: 200 GSG 202
>UniRef50_A4BRW4 Cluster: MOFRL family protein; n=1; Nitrococcus
mobilis Nb-231|Rep: MOFRL family protein - Nitrococcus
mobilis Nb-231
Length = 408
Score = 58.4 bits (135), Expect = 3e-07
Identities = 42/122 (34%), Positives = 64/122 (52%), Gaps = 5/122 (4%)
Query: 34 VEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEK 93
VE E A +PD + ++ + + LLV+ISGG S+L+ L + E
Sbjct: 83 VEQLESAHP-VPDTRSLVAGERLVRFLEAAPEQVHLLVMISGGASSLVELLPDGASPERL 141
Query: 94 IGLVKKLANSGADIKELNTVRKVISDLKGGQLA--VKAQPAQVVSLILSDIVGDPLDLIA 151
L ++L SG I E+N +RK +S +KGG+LA V +P V L++SD+ D +I
Sbjct: 142 AELNRRLLASGFAIHEINRIRKAVSRIKGGRLARWVAGRPTTV--LLISDVRDDDPAVIG 199
Query: 152 SG 153
SG
Sbjct: 200 SG 201
Score = 56.0 bits (129), Expect = 2e-06
Identities = 45/114 (39%), Positives = 66/114 (57%), Gaps = 10/114 (8%)
Query: 295 ILGGEITVAV-KGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDAA 353
I GGE TV++ + G+GGR Q LAL + L +D DI++L+AGTDG DG ++ A
Sbjct: 297 IWGGEPTVSLPENPGRGGRMQTLALAAAMALAG-RD-----DIWLLAAGTDGADGFSEDA 350
Query: 354 GAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
GA+ +S + G +V++ L + D F L + L + TG T TNVMD+
Sbjct: 351 GALIDGQTVSRGSVAGGNVNEALFDADAGGF--LAGSGDL-IRTGATGTNVMDL 401
>UniRef50_UPI00015B8F69 Cluster: UPI00015B8F69 related cluster; n=1;
unknown|Rep: UPI00015B8F69 UniRef100 entry - unknown
Length = 263
Score = 57.2 bits (132), Expect = 8e-07
Identities = 40/116 (34%), Positives = 54/116 (46%), Gaps = 9/116 (7%)
Query: 291 PLCLILGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPT 350
P L+ GGE TV ++G G+GGRN + L L I L TDG+DG
Sbjct: 150 PCVLLSGGETTVTIRGAGRGGRNVEFLLALGAEL------AGPPCIHALVGDTDGVDGID 203
Query: 351 DAAGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMD 406
+ AGAI + + + GL L ND + FF+ + + TG T TNV D
Sbjct: 204 EIAGAILRTDTPTRAATLGLSFRTSLDRNDGHGFFEALGD---AIITGPTLTNVND 256
>UniRef50_Q5LP57 Cluster: MOFRL family protein; n=1; Silicibacter
pomeroyi|Rep: MOFRL family protein - Silicibacter
pomeroyi
Length = 368
Score = 57.2 bits (132), Expect = 8e-07
Identities = 46/115 (40%), Positives = 61/115 (53%), Gaps = 16/115 (13%)
Query: 294 LILGGEITVAVK-GTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTDA 352
L+LGGE TV + G+GGRNQ LAL ++ + D + ++ GTDG DGPTDA
Sbjct: 263 LVLGGEPTVILPPNPGRGGRNQALALALAREI------AGDPGLVVVVGGTDGTDGPTDA 316
Query: 353 AGAIGYLNLISESTADGLDVDKYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
AGAI E A L A++ ++ L + L V TG T TNVMD+
Sbjct: 317 AGAIVSGRTWGEGAAQALAA----ADSGSW----LERAGALLV-TGPTGTNVMDL 362
Score = 56.0 bits (129), Expect = 2e-06
Identities = 37/121 (30%), Positives = 62/121 (51%), Gaps = 1/121 (0%)
Query: 33 NVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEE 92
+V+ E A +PD + ++ + + + LL+L+SGG S+L + TL++
Sbjct: 76 SVQLIEAAHP-VPDARSLVGGRALRQAVEAMPEGSHLLLLVSGGASSLAEDLVTGKTLDD 134
Query: 93 KIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIAS 152
L + + G DI +N R+ IS +KGG L + A+ L +SD+ GD L +I S
Sbjct: 135 LAALNRAMLAEGLDITAMNARRRQISRIKGGGLLAGFKGARADVLAISDVPGDDLMVIGS 194
Query: 153 G 153
G
Sbjct: 195 G 195
>UniRef50_Q0IHN8 Cluster: Putative uncharacterized protein
MGC147151; n=2; Tetrapoda|Rep: Putative uncharacterized
protein MGC147151 - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 150
Score = 51.6 bits (118), Expect = 4e-05
Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 10/86 (11%)
Query: 1 MSREVENILQSKIKYGIISIPMGSLDVFNKS----------RNVEYFEGAKDNLPDNSAQ 50
M+ VE I+ + G+ISIP G + ++ + EGA+ N+PD +A
Sbjct: 65 MAAAVEKIVGKHLLRGVISIPRGMEETLKQAGKREMLLSPDSRIRVMEGAEHNMPDKAAL 124
Query: 51 NTALKIKNLITQLNKDDLLLVLISGG 76
A +I++L +L + D+LLVLISGG
Sbjct: 125 EAAREIQSLAEKLTEQDILLVLISGG 150
>UniRef50_A5D6S7 Cluster: LOC553494 protein; n=4; Danio rerio|Rep:
LOC553494 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 981
Score = 40.3 bits (90), Expect = 0.093
Identities = 46/202 (22%), Positives = 91/202 (45%), Gaps = 15/202 (7%)
Query: 83 LPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDI 142
+ P T E + L ++E+N + I + G ++AQPA+V+ + I
Sbjct: 292 MENKPTTNSEVVILEHTFDVPDNKLEEVNDLVSDIEPVVSGSSKIEAQPAEVLQTVEQII 351
Query: 143 VGDPLDLIA------SGPT-VQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVF 195
+P ++ SGP+ +Q+ ++V V + + +ALP ++ LLE + + V
Sbjct: 352 TPEPETCLSNGDGPDSGPSKMQDAPHTPRSVKVFETPSPENALP--LELLLEKDNEVSVL 409
Query: 196 PT--NNTSNYIIGSNKISTKAAVVQCI-ELNYLPLVLSNKVTGNVQDVANKYSKLVTVIC 252
T + + + +N+I T ++ + + ELN K G ++ S T
Sbjct: 410 DTGVSAIAKDVAPANQIDTTPSLAEEVEELNTTKQAARPKSPGRLKSPGRPKSPART--- 466
Query: 253 KYLRQNLEIDELKSNIKKLEIS 274
K R + +E+K N+K+++ S
Sbjct: 467 KVERPGKDTEEIKENLKEVQHS 488
>UniRef50_Q9Y1J4 Cluster: Retinoid X receptor RXR-2; n=10;
Bilateria|Rep: Retinoid X receptor RXR-2 - Schistosoma
mansoni (Blood fluke)
Length = 1501
Score = 39.9 bits (89), Expect = 0.12
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 4/59 (6%)
Query: 188 NNGDNLVFPTNNTSNYIIGSN---KISTKAAVVQCIELNYL-PLVLSNKVTGNVQDVAN 242
NN +N+VF T+NT +II N K +T ++VQ EL ++ P+++S+ V N + N
Sbjct: 772 NNNNNVVFKTDNTKQHIIDQNILTKTATTTSIVQPSELCHIQPILISSPVKNNNNNTHN 830
>UniRef50_Q6LF21 Cluster: Putative DNA polymerase i; n=1; Plasmodium
falciparum 3D7|Rep: Putative DNA polymerase i -
Plasmodium falciparum (isolate 3D7)
Length = 1444
Score = 39.5 bits (88), Expect = 0.16
Identities = 35/135 (25%), Positives = 62/135 (45%), Gaps = 7/135 (5%)
Query: 155 TVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKA 214
T+ D +++ + + ++N + K+ NN +N NN +N +N IS +
Sbjct: 871 TLNAQDTSDQHDNYINEHNNYNKFIKNNPFYYNNNNNN----NNNNNNNNDNNNNISNRN 926
Query: 215 AVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEIS 274
+ + +NY L + K + D NK L + Y N I+E+ N K L+ +
Sbjct: 927 LMNNLVNINYTSL-YNKKKNSHPYDENNKLFFLNSSHNNYNNNNNNINEMSRN-KNLQTN 984
Query: 275 GTDLKVL-NEIKISN 288
LK+L +EI+ SN
Sbjct: 985 NKSLKILVDEIEKSN 999
>UniRef50_Q8AAI2 Cluster: Tyrosine-protein kinase ptk; n=9;
Bacteroides|Rep: Tyrosine-protein kinase ptk -
Bacteroides thetaiotaomicron
Length = 812
Score = 38.3 bits (85), Expect = 0.37
Identities = 39/166 (23%), Positives = 77/166 (46%), Gaps = 16/166 (9%)
Query: 30 KSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPIT 89
K ++ FE ++NL + +N ++ ++ K L+ +SG G + + + +
Sbjct: 564 KDGSIAVFEN-QNNLMSETFRNIRTNLQFMLQNDKKVILVTSTVSGEGKSFI---SANLA 619
Query: 90 LEEKIGLVKKLANSGADIKE--LNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPL 147
+ + L KK+ G DI++ LN V ++ + KG L + ++SL+ + L
Sbjct: 620 ISLSL-LGKKVVIVGLDIRKPGLNKVFRLSTKEKGITLYLANPETDLMSLVQPSDINQNL 678
Query: 148 DLIASGPTVQNT------DGANKAVDVLKK---YNLIDALPKSVQT 184
++ G N DG +KA+++LKK Y ++D P + T
Sbjct: 679 YILPGGTVPPNPTELLARDGLDKAIEILKKNFDYVILDTAPVGMVT 724
>UniRef50_A4XK74 Cluster: Methyl-accepting chemotaxis sensory
transducer; n=1; Caldicellulosiruptor saccharolyticus
DSM 8903|Rep: Methyl-accepting chemotaxis sensory
transducer - Caldicellulosiruptor saccharolyticus
(strain ATCC 43494 / DSM 8903)
Length = 605
Score = 38.3 bits (85), Expect = 0.37
Identities = 33/166 (19%), Positives = 79/166 (47%), Gaps = 8/166 (4%)
Query: 8 ILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDD 67
I +S IK ++ + GS +++N S+N++ NL D+ + + + Q + +
Sbjct: 290 ITKSSIKKDLLLLKGGSDEIYNFSKNIKEIADKMKNLSDSVSGIVNDVAQGAVHQAEEIE 349
Query: 68 LLLVLISGGGSALLPLPKSPITLEEKIGLVKK-LANSGADI----KELNTVRKVISDL-- 120
+ +++ L + I ++ + V + L NSG DI K++N + S++
Sbjct: 350 KAVTILNENIENLKSIVSQQIQTKDVLADVNQTLNNSGKDILSAAKDINLLSTEFSEIVQ 409
Query: 121 KGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAV 166
KG +L+ +A ++ +++I + ++++A +++ N V
Sbjct: 410 KGSKLSEEANEVMKITSTVAEI-SNQINMLALNASIEAARAGNVGV 454
>UniRef50_A5ULC4 Cluster: Archaeosine tRNA-ribosyltransferase; n=1;
Methanobrevibacter smithii ATCC 35061|Rep: Archaeosine
tRNA-ribosyltransferase - Methanobrevibacter smithii
(strain PS / ATCC 35061 / DSM 861)
Length = 250
Score = 38.3 bits (85), Expect = 0.37
Identities = 38/135 (28%), Positives = 62/135 (45%), Gaps = 10/135 (7%)
Query: 157 QNTDGANKAVDVLKKY-NL-IDALPKSVQTLLEN-----NGDNLVFPTNNTSNYIIG--S 207
+N D N AV KY +L ID L K ++ + N N D L+ + SN I+
Sbjct: 66 ENVDKCNVAVIQGSKYIDLRIDCL-KQLEEIGYNGFIIANSDELLLHPKDLSNMIVNLRK 124
Query: 208 NKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSN 267
N T + E +++PL+ V G + D +N YS L ++ +LE + N
Sbjct: 125 NMHPTSYLIFSFAEPSFMPLLAYIGVDGFLADSSNYYSYLNVLLTPTKTYDLETYPIYEN 184
Query: 268 IKKLEISGTDLKVLN 282
I + E+ +++ LN
Sbjct: 185 ITREELEEKNIEALN 199
>UniRef50_A7A6B7 Cluster: Putative uncharacterized protein; n=1;
Bifidobacterium adolescentis L2-32|Rep: Putative
uncharacterized protein - Bifidobacterium adolescentis
L2-32
Length = 140
Score = 37.9 bits (84), Expect = 0.50
Identities = 29/105 (27%), Positives = 55/105 (52%), Gaps = 11/105 (10%)
Query: 60 ITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISD 119
+ + K D+ L+ GG + LPL S I +L+N+ D + + +++++SD
Sbjct: 36 VRHIIKGDVYWALVPGGRTYKLPLSMS-------IDDFTRLSNTSDDTESVEQLKRILSD 88
Query: 120 LKGGQLA--VKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGA 162
G + A + +P QVV +LSD GD + + A G ++ ++G+
Sbjct: 89 FAGDKQAKQLNGEPVQVVFNLLSD-YGDAV-VRAQGASLGKSNGS 131
>UniRef50_Q4YRL8 Cluster: Putative uncharacterized protein; n=2;
Plasmodium (Vinckeia)|Rep: Putative uncharacterized
protein - Plasmodium berghei
Length = 1035
Score = 37.5 bits (83), Expect = 0.66
Identities = 34/135 (25%), Positives = 67/135 (49%), Gaps = 13/135 (9%)
Query: 164 KAVDVLKKYN---LIDALPKSVQTLLENNGD------NLVFPTNNTSNYIIGSNKISTKA 214
K +D +K+YN I+ L ++TLL +G+ N + N++ YII S S +
Sbjct: 840 KRIDDIKEYNKLYFINQLNIEIRTLLHEDGNFVLNIKNEISKLNSSDKYIISSQTTSASS 899
Query: 215 A-VVQCIELNYLPLVLSNKVTGNVQDVANKYS-KLVTVICK-YLRQNLEIDELKSNIKKL 271
++ I L + NV+ ++ S +TV+ K +L+ ++++ L + +K +
Sbjct: 900 NNIIGVIFLKLFDEIRDGFNVVNVEIISYGQSITSITVVDKDHLKNKIKMN-LVNKLKSI 958
Query: 272 EISGTDLKVLNEIKI 286
EI+G + N++ I
Sbjct: 959 EINGNKINYTNDLDI 973
>UniRef50_Q897I5 Cluster: Putative surface/cell-adhesion protein,
multiple big2 domain; n=1; Clostridium tetani|Rep:
Putative surface/cell-adhesion protein, multiple big2
domain - Clostridium tetani
Length = 1511
Score = 37.1 bits (82), Expect = 0.87
Identities = 25/106 (23%), Positives = 54/106 (50%), Gaps = 9/106 (8%)
Query: 94 IGLVKKLANSGADIKELNTVRKVISDLKGGQ-LAVKAQPAQVVSLILSDIVGDPLDLIAS 152
+GLV+ N A+ ++ + + +I +K G L+VKA+P + ++++ L +
Sbjct: 876 LGLVRNDKNLIAEEQKDDYLNSIIQSMKNGNDLSVKAKPTNIEKVVIA--------LTSI 927
Query: 153 GPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTN 198
G +V+N +G N ++ + N+ + L +S L+ + + P N
Sbjct: 928 GKSVENINGENLLKNIYQNSNISNGLNESAYALIALDSLSYKIPDN 973
>UniRef50_Q71TP0 Cluster: Sit; n=3; Enterobacteria phage P1|Rep: Sit
- Bacteriophage P1
Length = 1140
Score = 37.1 bits (82), Expect = 0.87
Identities = 22/74 (29%), Positives = 40/74 (54%), Gaps = 6/74 (8%)
Query: 103 SGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGA 162
S +++EL +R+ + DLKGG++A ++ VS + I D +A+ P+V
Sbjct: 19 SAKELEELAGIREAVEDLKGGRVATVYPVSRSVSALNRTIENSRPDFVANAPSV------ 72
Query: 163 NKAVDVLKKYNLID 176
+ V+ +K+ NL D
Sbjct: 73 DPIVEAMKRLNLGD 86
>UniRef50_A0V0Z2 Cluster: Putative uncharacterized protein; n=1;
Clostridium cellulolyticum H10|Rep: Putative
uncharacterized protein - Clostridium cellulolyticum H10
Length = 198
Score = 36.7 bits (81), Expect = 1.1
Identities = 19/53 (35%), Positives = 30/53 (56%), Gaps = 2/53 (3%)
Query: 17 IISIPM--GSLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDD 67
I+ IP+ GSL+ FN +YF A L + + + + K+ NLI L++DD
Sbjct: 101 ILPIPLIAGSLNNFNNEEEYQYFYSALTGLQNEAFSSVSQKLLNLIDNLDEDD 153
>UniRef50_Q8I5X6 Cluster: Putative uncharacterized protein; n=1;
Plasmodium falciparum 3D7|Rep: Putative uncharacterized
protein - Plasmodium falciparum (isolate 3D7)
Length = 652
Score = 36.7 bits (81), Expect = 1.1
Identities = 35/133 (26%), Positives = 62/133 (46%), Gaps = 18/133 (13%)
Query: 163 NKAVDVLK-KYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIE 221
NK+ + LK +Y+ I +P++ NN +N + T+N Y NKI+ + + Q
Sbjct: 204 NKSFNKLKGEYDEIKHIPQN-----NNNNNNNIMFTSNFDEYNYSMNKINPISIISQ--- 255
Query: 222 LNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLE---IDELKSNIKKLEISGTDL 278
+ + + + N+ N + ++ KY+ QN+ ID ++NI + + D
Sbjct: 256 VKIMDPINKEDMVNNID--KNDNTNKSDIVIKYVNQNVHQNGIDIEQNNISEKREASND- 312
Query: 279 KVLNEIKISNKKP 291
NE I NKKP
Sbjct: 313 ---NETYIKNKKP 322
>UniRef50_Q6BFI1 Cluster: Putative uncharacterized protein; n=1;
Paramecium tetraurelia|Rep: Putative uncharacterized
protein - Paramecium tetraurelia
Length = 665
Score = 36.7 bits (81), Expect = 1.1
Identities = 30/107 (28%), Positives = 55/107 (51%), Gaps = 8/107 (7%)
Query: 237 VQDVANKYSKLVT-VICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCLI 295
+ D+ N+Y VT ++C+ R +L + +LKS + ++ DLK LN+I+ ++ L +
Sbjct: 412 LNDIQNQYKLTVTKILCQ--RVSLMLKDLKSKLNQITTQNPDLKRLNQIQ--SQIYLLNL 467
Query: 296 LGGEITVAVKGTGKGGRNQQLALEFSKYLHKVKDQLNDFDIFILSAG 342
I + K G+ QL L+ +L+K+ +L+ D I G
Sbjct: 468 CNKNILYFLTDDFKEGKQSQLNLDV--FLNKIISKLSQ-DTLIYEKG 511
>UniRef50_A0CQ45 Cluster: Chromosome undetermined scaffold_24, whole
genome shotgun sequence; n=2; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_24,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 300
Score = 36.7 bits (81), Expect = 1.1
Identities = 33/111 (29%), Positives = 55/111 (49%), Gaps = 14/111 (12%)
Query: 239 DVANKYSKLVTVICKYLRQNLEID--ELKSNIK--KLEISGTDLKVLNEIKISNKKPLCL 294
D +YS + + RQNL I +L +K K EI T+L+ NE+K K L
Sbjct: 181 DFLKEYSTQIESVSPQERQNLAIQLKQLTKELKTTKNEIENTNLQTANELKTEIKSMLNK 240
Query: 295 IL--GGEITVAVKGTGK-------GGRNQQLALEFSKYLHKVKDQLNDFDI 336
+L G++T ++ G+GK G + + +F+K L+ V+ + F+I
Sbjct: 241 LLKAKGKMTESIVGSGKDSVLMLRGSQYKPTLADFAKQLNAVR-SIETFNI 290
>UniRef50_Q4FST6 Cluster: ABC sulfate/thiosulfate transporter,
periplasmic solute-binding protein; n=9;
Proteobacteria|Rep: ABC sulfate/thiosulfate transporter,
periplasmic solute-binding protein - Psychrobacter
arcticum
Length = 394
Score = 36.3 bits (80), Expect = 1.5
Identities = 20/53 (37%), Positives = 29/53 (54%)
Query: 256 RQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILGGEITVAVKGTG 308
R +++ + N IS TD +V+ I NK P LI+GG +T+AV TG
Sbjct: 5 RASMQTTNIAKNQPLRHISMTDNQVIQNKVIQNKVPRTLIMGGALTMAVFMTG 57
>UniRef50_A0J3G5 Cluster: Putative uncharacterized protein; n=1;
Shewanella woodyi ATCC 51908|Rep: Putative
uncharacterized protein - Shewanella woodyi ATCC 51908
Length = 856
Score = 36.3 bits (80), Expect = 1.5
Identities = 26/95 (27%), Positives = 50/95 (52%), Gaps = 3/95 (3%)
Query: 96 LVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPL---DLIAS 152
L+KK + DI ++ +R+++SD K Q AV ++ S+ +SD + L +I+S
Sbjct: 266 LIKKKYLTSFDIAPIDHIRELVSDNKEIQDAVTQLLSKEGSINISDKIKSQLYLYGIISS 325
Query: 153 GPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLE 187
+ N NK +++ + I +L + QT+L+
Sbjct: 326 ENNIDNIKIKNKIIELSLSLSWIKSLSDNTQTILD 360
>UniRef50_Q4CSS9 Cluster: Protein kinase, putative; n=2; Trypanosoma
cruzi|Rep: Protein kinase, putative - Trypanosoma cruzi
Length = 922
Score = 36.3 bits (80), Expect = 1.5
Identities = 20/83 (24%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 27 VFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKS 86
+ N R Y GAKD + + + K + T +++ L + G +LP+PK
Sbjct: 465 IVNSGRYTHYLGGAKDRIKSELSL-LGKRSKRMATNAERENAFLHQVDVNGEIILPVPKE 523
Query: 87 PITLEEKIGLVKKLANSGADIKE 109
+ EK ++ K N ++K+
Sbjct: 524 KVFAVEKGIVLDKENNERVNVKD 546
>UniRef50_Q1QEB0 Cluster: Putative uncharacterized protein; n=1;
Psychrobacter cryohalolentis K5|Rep: Putative
uncharacterized protein - Psychrobacter cryohalolentis
(strain K5)
Length = 660
Score = 35.9 bits (79), Expect = 2.0
Identities = 23/92 (25%), Positives = 46/92 (50%), Gaps = 2/92 (2%)
Query: 96 LVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPT 155
L K++ + A+ KEL ++ +VI + K A+ Q ++ S+I D++ D
Sbjct: 391 LTKQVKSLQAEKKELESINEVIRERKDFSEAIYNQKYKLFSII--DLINPSSDTKIDSQL 448
Query: 156 VQNTDGANKAVDVLKKYNLIDALPKSVQTLLE 187
++ LKKYN+I+ + ++ +T+ E
Sbjct: 449 IELRKDLQAITGELKKYNIINFIEEAEKTINE 480
>UniRef50_A6LUV0 Cluster: 2-dehydropantoate 2-reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2-dehydropantoate 2-reductase - Clostridium beijerinckii
NCIMB 8052
Length = 307
Score = 35.9 bits (79), Expect = 2.0
Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 6/85 (7%)
Query: 125 LAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQT 184
+ VK + + + +VGD +I P + DG NK L+K + DA+ S+ +
Sbjct: 75 VCVKGYSLKAAAKAILPMVGDHTLII---PIINGVDGGNKLYSYLRKGKVTDAI-MSISS 130
Query: 185 LLENNGDNLVFPTNNTSNYIIGSNK 209
+E GD ++ T+ + I SNK
Sbjct: 131 KIE--GDGVIKHTSQNTRIFISSNK 153
>UniRef50_A5TSU9 Cluster: Possible TPS family two-partner secretion
family protein TpsA; n=4; Fusobacterium nucleatum|Rep:
Possible TPS family two-partner secretion family protein
TpsA - Fusobacterium nucleatum subsp. polymorphum ATCC
10953
Length = 2751
Score = 35.9 bits (79), Expect = 2.0
Identities = 75/322 (23%), Positives = 125/322 (38%), Gaps = 18/322 (5%)
Query: 23 GSLDVFNKSRNVEYFEGAKDNLPDNSAQNTA-LKIKNLITQLNKDDLLLVLISGGGSALL 81
G+L + N N EG + N NS NT + IKN +T N ++ G +
Sbjct: 562 GNLKIANNLNNSGIIEGLELNT--NSIDNTGNITIKNKLTSQNLNNKKNTANINAGFLDV 619
Query: 82 PLPKSPITLEEKIGL-VKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILS 140
S + + I L + L NSG+ + T + I+ KG A +V+
Sbjct: 620 QNKISSVGNIKAITLKIYNLDNSGSILTNSLTTSENIN--KGSITAKNISSQNLVNS--G 675
Query: 141 DIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNT 200
++ D + ++ T N+ AN+ + K N + K+ +T+ N N+V N
Sbjct: 676 SVISDNIT-VSKNITNTNSIFANEKISADKISNSNKLVAKNTETINLTNTGNIVVKENLK 734
Query: 201 SNYIIGSNKISTKAAVVQCIELNYLPLVLSN-KVTGNVQDVANKYSKLVTVI-CKYLRQN 258
+ I SN I + N+ L+ N V ++ ++ K + L T I ++ N
Sbjct: 735 TKDITNSNSIKVGGNLNTDKLENFKTLIAKNITVEKSLDNINGKITSLNTNINTSDIKNN 794
Query: 259 LEIDELKSNI-----KKLEISG--TDLKVLNEIKISNKKPLCLILGGEITVAVKGTGKGG 311
I + NI L + G T LN S + + L G+IT + G
Sbjct: 795 NGIIQAIKNINITTTNNLSLDGNYTANDTLNIKAKSLENNVDLKNDGKITFNLSGNLTNN 854
Query: 312 RNQQLALEFSKYLHKVKDQLND 333
+N + KV + ND
Sbjct: 855 KNISSTGNLNIKAQKVSNTKND 876
>UniRef50_Q10411 Cluster: Sporulation-specific protein 15; n=1;
Schizosaccharomyces pombe|Rep: Sporulation-specific
protein 15 - Schizosaccharomyces pombe (Fission yeast)
Length = 1957
Score = 35.9 bits (79), Expect = 2.0
Identities = 44/197 (22%), Positives = 91/197 (46%), Gaps = 13/197 (6%)
Query: 88 ITLEEKIGLVKKLANSGADI-KELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDP 146
I L++ G +K + +D+ K+L ++ IS+LK ++ ++Q V L + +
Sbjct: 927 IRLDKLTGKLKIEESKSSDLGKKLTARQEEISNLKEENMS-QSQAITSVKSKLDETLSKS 985
Query: 147 LDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIG 206
L A ++N K +V + N + A + + L+NNG+N+
Sbjct: 986 SKLEADIEHLKN-----KVSEVEVERNALLASNERLMDDLKNNGENIASLQTEIEKKRAE 1040
Query: 207 SNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYL----RQNLEID 262
++ + +K +VV N L++S++ +++D N+ + + K L ++N+E++
Sbjct: 1041 NDDLQSKLSVVSSEYENL--LLISSQTNKSLEDKTNQLKYIEKNVQKLLDEKDQRNVELE 1098
Query: 263 ELKSNIKKLEISGTDLK 279
EL S KL +K
Sbjct: 1099 ELTSKYGKLGEENAQIK 1115
>UniRef50_Q6F1S3 Cluster: Putative NAD kinase; n=1; Mesoplasma
florum|Rep: Putative NAD kinase - Mesoplasma florum
(Acholeplasma florum)
Length = 259
Score = 35.5 bits (78), Expect = 2.6
Identities = 25/58 (43%), Positives = 37/58 (63%), Gaps = 9/58 (15%)
Query: 260 EIDELKSNIKK---LEIS---GTDLKVLNEIK-ISNKKPL--CLILGGEITVAVKGTG 308
+I E+ +NI+K +EIS D KV+NEIK I+N +PL +++ GE+ KGTG
Sbjct: 83 DIQEILNNIEKQKPIEISVLEANDYKVINEIKIINNLRPLEADVMIDGELLETFKGTG 140
>UniRef50_A0QNZ8 Cluster: Secreted protein; n=6; Mycobacterium|Rep:
Secreted protein - Mycobacterium smegmatis (strain ATCC
700084 / mc(2)155)
Length = 319
Score = 35.5 bits (78), Expect = 2.6
Identities = 36/109 (33%), Positives = 54/109 (49%), Gaps = 15/109 (13%)
Query: 105 ADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGP-------TVQ 157
A ++E+ T V DL G A+ P + ++I +D + DPL L A P T
Sbjct: 196 ATVEEIRTKGTVPDDLPEGLTAI-VNPGNLNAIIEADKI-DPLALAAQLPDDMPVLLTCS 253
Query: 158 NTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVF---PTNNTSNY 203
+TD A + + + LIDAL + T++E G N V PT+N +NY
Sbjct: 254 DTD-AQASCETERP--LIDALHHTALTVIELKGVNHVLRDDPTDNIANY 299
>UniRef50_Q8IAM6 Cluster: Putative uncharacterized protein MAL8P1.150;
n=4; Plasmodium|Rep: Putative uncharacterized protein
MAL8P1.150 - Plasmodium falciparum (isolate 3D7)
Length = 2245
Score = 35.5 bits (78), Expect = 2.6
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 5/127 (3%)
Query: 171 KYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNK--ISTKAAVVQCIELNYLPLV 228
K N I+ K + ++ + VFP+N+T++ SN I+ + +V +LN PLV
Sbjct: 2028 KNNYINHFSKQIISVQNETVKSSVFPSNSTTSCNDNSNNDDINYEYDLVVVKDLNEAPLV 2087
Query: 229 -LSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKIS 287
++ D N+ +L+ +C + I +++ K IS +LK + +K+
Sbjct: 2088 PRLTAYCMSLIDSLNQEEQLLAKLCSFFNNTFNIKKMECIYPKY-ISRCELKKI-IVKLV 2145
Query: 288 NKKPLCL 294
K CL
Sbjct: 2146 EKNVFCL 2152
>UniRef50_Q7R8P5 Cluster: OGG1 protein type 2e-related; n=2;
Plasmodium (Vinckeia)|Rep: OGG1 protein type 2e-related
- Plasmodium yoelii yoelii
Length = 571
Score = 35.5 bits (78), Expect = 2.6
Identities = 30/108 (27%), Positives = 56/108 (51%), Gaps = 8/108 (7%)
Query: 167 DVLKKYNLIDALPKSVQTLLENNGDNL--VFPTNNTSNYIIGSNKISTKAAVVQCIELNY 224
D+ +K N I+ + K +T NN +N TNNT+N +NKI+ K + + ++ +
Sbjct: 49 DLRRKKNKINKMNKMNKTNNTNNTNNTNNTNNTNNTNN----TNKITNKIEIKKEVQYDT 104
Query: 225 LPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLE 272
P +++N + N+ ++K SK T + K + N I + N +L+
Sbjct: 105 PPKLINNYNSKNLN--SDKISKSFTNLIKNYKNNWRILNVTPNDLQLK 150
>UniRef50_Q4UGA6 Cluster: Putative uncharacterized protein; n=2;
Theileria|Rep: Putative uncharacterized protein -
Theileria annulata
Length = 915
Score = 35.5 bits (78), Expect = 2.6
Identities = 35/134 (26%), Positives = 63/134 (47%), Gaps = 12/134 (8%)
Query: 156 VQNTDGANKAVDVLKK--YNLIDALPKSVQTLLENNGDNLVFP----TNNTSNYIIGSNK 209
+ ++G K+ DVLK +NL L + +Q + N DN T+NT++ ++ N+
Sbjct: 424 IAKSEGLIKSNDVLKAKIFNLQSELSQ-LQNMSNTNTDNKYTEDTKETDNTTDAVV-DNE 481
Query: 210 ISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIK 269
I+ + I+ N V ++++ + +L+ + K + N+EI EL+
Sbjct: 482 INE----IDEIDKNLNSTVQNDEIIKLSNQITQLTDELIQLRDKLTQSNIEISELRERNS 537
Query: 270 KLEISGTDLKVLNE 283
LE LK LNE
Sbjct: 538 TLEGDNLRLKELNE 551
>UniRef50_Q4J7L2 Cluster: Conserved protein; n=2; Sulfolobus|Rep:
Conserved protein - Sulfolobus acidocaldarius
Length = 442
Score = 35.5 bits (78), Expect = 2.6
Identities = 45/180 (25%), Positives = 75/180 (41%), Gaps = 17/180 (9%)
Query: 220 IELNYLPLVLSNKVTGNVQDV-ANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDL 278
+ LN L L N++ G DV N +K+V + K R+ + +LK++ + I G
Sbjct: 156 VPLNVLRY-LKNRLRGFPIDVFINHKNKIVYTLYKGFREKFIVRKLKNSPNVVRIYGMSP 214
Query: 279 KVLNEIKISNKK------PLCLILGGEITVAVKGTGKGGRNQQLA--------LEFSKYL 324
LN + + N P I G ++ K T K A LE L
Sbjct: 215 GQLNSLGVLNSGKGKVLYPAAAIEGELLSFREKRTDKDDYMVFFARLLPLKGTLELPFIL 274
Query: 325 HKVKDQLNDFDIFILSAGTDGIDGPTDAAGAIGYLNLISE-STADGLDVDKYLANNDTYN 383
KVK+ + + +FI+ + I G + + + NL+ E +D + YL N+ Y+
Sbjct: 275 SKVKEIVKEAKLFIVGKFPEDIRGKKNESFQDYFFNLVEEMGLSDHIVYKGYLTGNELYD 334
>UniRef50_Q60390 Cluster: Methyl-coenzyme M reductase II subunit
beta; n=46; Archaea|Rep: Methyl-coenzyme M reductase II
subunit beta - Methanococcus jannaschii
Length = 447
Score = 35.5 bits (78), Expect = 2.6
Identities = 42/152 (27%), Positives = 67/152 (44%), Gaps = 8/152 (5%)
Query: 48 SAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGADI 107
+A+ A KIK ++ DD ++ LI+GG LL LP + + V L GA +
Sbjct: 81 NAEIIAEKIKRMVQIEEDDDTVVKLINGGKQLLLQLPSKRLRVAADY-TVSALIGGGATV 139
Query: 108 KELNTVRKV-ISDLKGGQLAVKAQPAQVVSL---ILSDIVGDPLDLIASGPTVQNTDGAN 163
+ + V + D + AV + Q V ++ ++G P+ L G ++N AN
Sbjct: 140 QAIVDAFDVDMFDAPVVKTAVMGRYPQTVDFHGANIATLLGPPVLLEGLGYGLRNI-MAN 198
Query: 164 KAVDVLKKYNLIDALPKSV--QTLLENNGDNL 193
V V +K L S+ QT + GD L
Sbjct: 199 HIVAVTRKKTLNAVALASILEQTAMFETGDAL 230
>UniRef50_A5N599 Cluster: IlvE1; n=8; Bacteria|Rep: IlvE1 -
Clostridium kluyveri DSM 555
Length = 412
Score = 35.1 bits (77), Expect = 3.5
Identities = 22/64 (34%), Positives = 33/64 (51%), Gaps = 1/64 (1%)
Query: 240 VANKY-SKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILGG 298
V KY ++VTV + L +++ I K + L L+++K NKK +CLI GG
Sbjct: 255 VVKKYVDEIVTVSDQQLMEDVYILLEKHKLVAEATGAMSLAALSKLKFKNKKVVCLISGG 314
Query: 299 EITV 302
I V
Sbjct: 315 NIDV 318
>UniRef50_Q86I70 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum (Slime mold)
Length = 616
Score = 35.1 bits (77), Expect = 3.5
Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 2/74 (2%)
Query: 188 NNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKL 247
NN +N NN +N +N +K + + LN L L+++NK+T NV + KY K
Sbjct: 204 NNNNNNNNNNNNNNNNNNNNNNEFSKLEIFK--NLNVLELLINNKITLNVLEEYGKYIKK 261
Query: 248 VTVICKYLRQNLEI 261
V + Y ++ EI
Sbjct: 262 VFGLNLYYCRDKEI 275
>UniRef50_Q54DE7 Cluster: Patatin domain-containing protein; n=1;
Dictyostelium discoideum AX4|Rep: Patatin
domain-containing protein - Dictyostelium discoideum AX4
Length = 1673
Score = 35.1 bits (77), Expect = 3.5
Identities = 24/68 (35%), Positives = 32/68 (47%), Gaps = 6/68 (8%)
Query: 182 VQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVA 241
V L NN N NN +N I SN K AVV C+E N ++ + V G V +
Sbjct: 1308 VHNFLHNNNHNNNNNNNNNNNIFINSN---IKVAVVSCLEEN---IIKTTNVVGGVNNSN 1361
Query: 242 NKYSKLVT 249
N+ S +T
Sbjct: 1362 NRSSIKLT 1369
>UniRef50_Q2CF81 Cluster: Putative uncharacterized protein; n=1;
Oceanicola granulosus HTCC2516|Rep: Putative
uncharacterized protein - Oceanicola granulosus HTCC2516
Length = 369
Score = 34.7 bits (76), Expect = 4.6
Identities = 21/69 (30%), Positives = 33/69 (47%)
Query: 27 VFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKS 86
VF+ +EY EG D NT ++ +T N D+ ++SG G LP+P
Sbjct: 225 VFSGQGGLEYTEGDARMAIDFEDFNTNQGVRARVTNRNAYDVNGNIVSGSGEGQLPMPDL 284
Query: 87 PITLEEKIG 95
+T+E+ G
Sbjct: 285 ILTVEQGEG 293
>UniRef50_Q2B211 Cluster: Serine protease Do; n=1; Bacillus sp. NRRL
B-14911|Rep: Serine protease Do - Bacillus sp. NRRL
B-14911
Length = 409
Score = 34.7 bits (76), Expect = 4.6
Identities = 24/100 (24%), Positives = 45/100 (45%), Gaps = 7/100 (7%)
Query: 119 DLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKA-VDVLKKYNLIDA 177
D+ GGQ + A + + I+ + G +GA+KA V ++K N +
Sbjct: 59 DVSGGQASSTADANK------TGIIPEQTSAHTEGSLADIVEGASKAIVGIVKSENRANQ 112
Query: 178 LPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVV 217
+ QT+ +G ++F N S YI+ +N + A+ +
Sbjct: 113 FSNTSQTVESGSGSGVIFKKENGSAYILTNNHVVEGASKI 152
>UniRef50_Q9N9H5 Cluster: Guanylyl cyclase; n=3; Plasmodium
falciparum|Rep: Guanylyl cyclase - Plasmodium falciparum
Length = 4226
Score = 34.7 bits (76), Expect = 4.6
Identities = 22/62 (35%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 243 KYSKLVTVICKYLRQNLEIDEL---KSNIKKLEISGTDLKVLNEIKISNKKP---LCLIL 296
+YS V+ +CK+L ++ +I SN KKL+ G L L +++ KKP LCL++
Sbjct: 1911 EYSLHVSFLCKFLNKHTKIFHAALENSNAKKLKREGMALYELFQLEKEEKKPYENLCLLV 1970
Query: 297 GG 298
G
Sbjct: 1971 NG 1972
>UniRef50_Q4Z3Z7 Cluster: MRNA (N6-adenosine)-methyltransferase,
putative; n=8; Eukaryota|Rep: MRNA
(N6-adenosine)-methyltransferase, putative - Plasmodium
berghei
Length = 774
Score = 34.7 bits (76), Expect = 4.6
Identities = 21/46 (45%), Positives = 28/46 (60%), Gaps = 1/46 (2%)
Query: 245 SKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKK 290
S L+ CK L + EID KSN K +IS T +++L EIK N+K
Sbjct: 182 SILLLFTCKILLEMCEIDGWKSNNAK-KISITSVEILREIKSRNRK 226
>UniRef50_Q234L4 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 1424
Score = 34.7 bits (76), Expect = 4.6
Identities = 42/146 (28%), Positives = 68/146 (46%), Gaps = 9/146 (6%)
Query: 147 LDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIG 206
LD IA QN K+++V ++ LI L S+Q ++N N VF + + N I
Sbjct: 1256 LDCIAKLNNDQNIKVQVKSLEVFQQ--LIPILQDSIQINIQNVM-NSVFSSCGSQNMQIK 1312
Query: 207 SNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKS 266
+++ ++ YL L+N G++ AN SK + +I E+ + K
Sbjct: 1313 RKAEEVLQTIMENVDSQYLFEPLNN---GSL--FANPKSKPI-IIDNLANICNEVSKRKQ 1366
Query: 267 NIKKLEISGTDLKVLNEIKISNKKPL 292
NI I+ T K+L E KI ++PL
Sbjct: 1367 NIFHKSITKTIQKLLQENKIELRQPL 1392
>UniRef50_UPI00006CCFDA Cluster: Protein kinase domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Protein
kinase domain containing protein - Tetrahymena
thermophila SB210
Length = 1609
Score = 34.3 bits (75), Expect = 6.1
Identities = 24/118 (20%), Positives = 53/118 (44%), Gaps = 5/118 (4%)
Query: 183 QTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVAN 242
+T ++N N FP + S + +NK++TK +++ E N+L + N Q +
Sbjct: 1442 KTQYQSNDTNSSFPVSPLSTQGLKANKVNTKNGIIEISENNWLSIECQNG-----QLIFK 1496
Query: 243 KYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILGGEI 300
V+C+ L+ + ++++ + K E+ +SN + ++G +I
Sbjct: 1497 ISPNGEQVVCQTLKSKTPLVKIQNEKGTFMLMSNQPKQNYEVSLSNGYKVSHVIGTDI 1554
>UniRef50_UPI000051A58B Cluster: PREDICTED: similar to solute
carrier family 39 (zinc transporter), member 7; n=1;
Apis mellifera|Rep: PREDICTED: similar to solute carrier
family 39 (zinc transporter), member 7 - Apis mellifera
Length = 404
Score = 34.3 bits (75), Expect = 6.1
Identities = 33/161 (20%), Positives = 74/161 (45%), Gaps = 11/161 (6%)
Query: 219 CIELNYLPLVLSNKVTGNVQ-DVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTD 277
C+ L + ++ K ++ D ++ ++ +++ ++N + ++L+ +I K ++ +
Sbjct: 188 CVLLGIIMFLIVEKAVRIIKSDHSHLHTNKISITENLSKENKDDNKLQKDIDKFDVISKE 247
Query: 278 LK---VLNEIKISNKKPLCLILGGEIT--VAVKGTGKGGRNQQLALEFSKYLHKVKDQLN 332
+ + NEIKI+ L T +A+ + G+N F+ LH++ ++
Sbjct: 248 KETKNIQNEIKIAGYLNLVADFLHNFTDGLAIGASYLAGKNIGYITTFTILLHEIPHEIG 307
Query: 333 DFDIFILSAGTDGIDGPTDAAGAIG-----YLNLISESTAD 368
DF I I S + + AIG Y++L++E D
Sbjct: 308 DFAILIQSGYSKQKAMLLQLSTAIGALLGTYVSLLAEGMGD 348
>UniRef50_UPI0000397283 Cluster: COG5295: Autotransporter adhesin;
n=1; Haemophilus somnus 2336|Rep: COG5295:
Autotransporter adhesin - Haemophilus somnus 2336
Length = 2179
Score = 34.3 bits (75), Expect = 6.1
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 2/65 (3%)
Query: 179 PKSVQTLLENNGDNLVFPTNNTSN-YIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNV 237
PKS+ +L NNG ++ F TS+ IGS KI T A ++ E + N V G V
Sbjct: 1648 PKSLDSLDPNNGPSIEFSAKKTSDGKTIGSGKI-TGLADIKSDEKDGTVATNKNYVDGKV 1706
Query: 238 QDVAN 242
+D+ N
Sbjct: 1707 EDLNN 1711
>UniRef50_UPI0000F32DF2 Cluster: UPI0000F32DF2 related cluster; n=1;
Bos taurus|Rep: UPI0000F32DF2 UniRef100 entry - Bos
Taurus
Length = 3146
Score = 34.3 bits (75), Expect = 6.1
Identities = 24/87 (27%), Positives = 42/87 (48%), Gaps = 7/87 (8%)
Query: 196 PTNNTSNYIIGSNKISTKA--AVVQCIE-LNYLPLVLSNK----VTGNVQDVANKYSKLV 248
PT N +I + ++ K + ++C+E LNY+ LS K + QD K +
Sbjct: 470 PTRNVGLLLIDTKQLKEKLIPSPLRCLEVLNYMLPRLSKKKVDAIISEAQDAEYKLEFVP 529
Query: 249 TVICKYLRQNLEIDELKSNIKKLEISG 275
T +Y+ + +DE++ I+ LE G
Sbjct: 530 TTTIEYVNSLVFLDEIQERIESLEDEG 556
>UniRef50_A7GY70 Cluster: Dead/deah box helicase:hd domain; n=2;
Campylobacter|Rep: Dead/deah box helicase:hd domain -
Campylobacter curvus 525.92
Length = 724
Score = 34.3 bits (75), Expect = 6.1
Identities = 25/94 (26%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Query: 315 QLALEFSKYLHKVKDQLNDFDIFILSAGTDGIDGPTD-AAGAIGYLNLISESTADGLDVD 373
+L F KY++ D++ D + +LSA ++ D + A G+L+++S D +
Sbjct: 40 KLKQNFQKYINNPNDKITDKNHSLLSAYIFLLNSTFDELSSAFGFLSIVSHH-GDVENFS 98
Query: 374 KYLANNDTYNFFKLFKNDHLHVFTGHTNTNVMDI 407
+ +ANN NF K F+ H F N +++
Sbjct: 99 ELIANNK--NFGKYFELSHEFDFWDEVVNNALNL 130
>UniRef50_A0NTH0 Cluster: Transcriptional regulator; n=1; Stappia
aggregata IAM 12614|Rep: Transcriptional regulator -
Stappia aggregata IAM 12614
Length = 242
Score = 34.3 bits (75), Expect = 6.1
Identities = 28/86 (32%), Positives = 43/86 (50%), Gaps = 8/86 (9%)
Query: 109 ELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDI--VGDPL----DLIASGPTVQNTDGA 162
E+ T ++ + G+ AV A Q+ LI S VGD L +L A +NT
Sbjct: 2 EVETGGSLMRSGQAGESAVDAVVQQIRDLIASSRLKVGDSLPTERELCAQFNASRNT--V 59
Query: 163 NKAVDVLKKYNLIDALPKSVQTLLEN 188
+A+ +LK Y L+D PK T+++N
Sbjct: 60 REAMRILKAYGLVDVRPKIGATIIDN 85
>UniRef50_A7NV36 Cluster: Chromosome chr18 scaffold_1, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr18 scaffold_1, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 1855
Score = 34.3 bits (75), Expect = 6.1
Identities = 40/182 (21%), Positives = 83/182 (45%), Gaps = 9/182 (4%)
Query: 96 LVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPT 155
+V K+ S A ++ L + +VI++ + + AQ +LSD L++ +
Sbjct: 990 MVSKVDASNALVQRLQSELEVIANRLKVSFEAEEKYAQKSGELLSDFAC--LEVELQELS 1047
Query: 156 VQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTN---NTSNYIIGSNKIST 212
+N D A ++L + + L KS T+ + N V T+ T + +++IS+
Sbjct: 1048 SKNRDLAQ---EILGLETVTEELGKSKSTIADITLRNQVLMTSLQVKTDESVKLASEISS 1104
Query: 213 KAAVVQCIELNY-LPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKL 271
++C++ + L +K+ G V D+ + + + + +QN E+D K + L
Sbjct: 1105 LKESLRCLQEELCVERGLRDKLEGTVGDLTFQLDEKHRHLINFDQQNAELDHFKQQLSDL 1164
Query: 272 EI 273
E+
Sbjct: 1165 EL 1166
>UniRef50_Q8SCK9 Cluster: PHIKZ303; n=1; Pseudomonas phage
phiKZ|Rep: PHIKZ303 - Pseudomonas phage phiKZ
Length = 646
Score = 34.3 bits (75), Expect = 6.1
Identities = 23/72 (31%), Positives = 36/72 (50%), Gaps = 6/72 (8%)
Query: 145 DPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNLVFPTNNTSN-- 202
DPL I +GPT + DG VD + N AL + ++ +L N + + + + N SN
Sbjct: 237 DPLPAIVTGPTTEPIDGEILPVDAI---NNSAALEEFIEEVLSTNPEFIKYQSMNDSNID 293
Query: 203 -YIIGSNKISTK 213
Y+ G + I K
Sbjct: 294 SYLTGDDWIILK 305
>UniRef50_Q4UAJ2 Cluster: Adapter protein, putative; n=1; Theileria
annulata|Rep: Adapter protein, putative - Theileria
annulata
Length = 1045
Score = 34.3 bits (75), Expect = 6.1
Identities = 27/94 (28%), Positives = 52/94 (55%), Gaps = 9/94 (9%)
Query: 182 VQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIEL---NYLPLVLSNKVTGNVQ 238
++ L+++N N + NN I +NK++ + +CI+L N + L+L +T Q
Sbjct: 614 IELLIKSN--NTFYILNNLIKLIKNNNKLNINWLINKCIKLLAENNIILLLIYLLTHKTQ 671
Query: 239 DVANKYSKLVTVICKYLRQNLEIDELKSNIKKLE 272
++ N+ +KL+ + L + LE+ L+ NI+ LE
Sbjct: 672 ELTNELNKLMEE--EILEEKLEM--LEKNIEILE 701
>UniRef50_A0CZ47 Cluster: Chromosome undetermined scaffold_312,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_312,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 585
Score = 34.3 bits (75), Expect = 6.1
Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 1/67 (1%)
Query: 2 SREVENILQSKIKYGIISIPMGSLDVFNKSRNVEYFEGAKDNLPDNSAQNT-ALKIKNLI 60
S++ +I+++ +Y LD N++ N EY+E + +++ + T +LKI
Sbjct: 433 SKKQSSIIKNNFQYVKADFQKLKLDTLNQNSNKEYWEIYHKMVEESTRKGTTSLKITKQY 492
Query: 61 TQLNKDD 67
T+LNKD+
Sbjct: 493 TELNKDN 499
>UniRef50_A0C1B6 Cluster: Chromosome undetermined scaffold_141,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_141,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 612
Score = 34.3 bits (75), Expect = 6.1
Identities = 42/182 (23%), Positives = 76/182 (41%), Gaps = 5/182 (2%)
Query: 108 KELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVD 167
+EL ++K++ D+ Q A + L+L +G + + N
Sbjct: 61 RELKKLQKIMDDISSKQCAFNIHINKYADTQCKKTFTSALELQHAGQQLLLSTFCNHKTQ 120
Query: 168 V---LKKYN-LIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELN 223
+ L KYN LI +P + NL+ N ++ +++ + +
Sbjct: 121 LQTFLTKYNNLITYIPFWEYAQQLESKYNLIDIDFNLIQSMLDELQLNYTNMKKEQEKNK 180
Query: 224 YLPLVLSNKVTGNVQDVANKYSKLVTVICK-YLRQNLEIDELKSNIKKLEISGTDLKVLN 282
L V S + N Q+V K +++ I K +Q L+IDELK I KL+ ++LK N
Sbjct: 181 KLHKVASIQTNPNQQEVIYKEKEVIKEIYKDNPQQQLQIDELKKQITKLKEEISNLKTQN 240
Query: 283 EI 284
++
Sbjct: 241 QL 242
>UniRef50_Q6BUR4 Cluster: Similar to CA4464|IPF9828 Candida
albicans; n=1; Debaryomyces hansenii|Rep: Similar to
CA4464|IPF9828 Candida albicans - Debaryomyces hansenii
(Yeast) (Torulaspora hansenii)
Length = 851
Score = 34.3 bits (75), Expect = 6.1
Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 5/89 (5%)
Query: 208 NKISTKAAVVQ----CIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDE 263
NK T AA + C +L+ + S K+ N + + N++ K + RQ+L ++
Sbjct: 740 NKEYTSAAYFEFAKTCFKLSSQDQLASLKLKVNEKQLLNRFLKFLNTSISGFRQSLNLEM 799
Query: 264 LKSNIKKLEISGTDLKVLNEIKISNKKPL 292
LK KLE D+K L+E++ + K L
Sbjct: 800 LKECF-KLEKDMADMKQLDELQEHSAKSL 827
>UniRef50_UPI0000DB797F Cluster: PREDICTED: similar to CG4840-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG4840-PA
- Apis mellifera
Length = 702
Score = 33.9 bits (74), Expect = 8.1
Identities = 17/57 (29%), Positives = 35/57 (61%)
Query: 236 NVQDVANKYSKLVTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEIKISNKKPL 292
N+Q + + +++T + + ++ LE+++L+ N KK+E + T LK+L + KK L
Sbjct: 534 NLQSKSKEIEQVMTTLEETKQRMLELEDLEQNRKKMERNETLLKILQQRLTDMKKTL 590
>UniRef50_UPI00006CC842 Cluster: hypothetical protein
TTHERM_00285670; n=1; Tetrahymena thermophila SB210|Rep:
hypothetical protein TTHERM_00285670 - Tetrahymena
thermophila SB210
Length = 1137
Score = 33.9 bits (74), Expect = 8.1
Identities = 20/84 (23%), Positives = 37/84 (44%)
Query: 207 SNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDELKS 266
S+K + V+Q + N NK+ N++++ + + + Q E++ LKS
Sbjct: 829 SDKDENRDLVIQLEKKNQYQQEYINKLESNIKEIEQRTKEFDQAQSTIIEQKEELENLKS 888
Query: 267 NIKKLEISGTDLKVLNEIKISNKK 290
N ++ TD + E I KK
Sbjct: 889 NFQRQAKKMTDTLQMKEKDIDEKK 912
>UniRef50_Q6TUT7 Cluster: 78R; n=7; Poxviridae|Rep: 78R - Yaba
monkey tumor virus (YMTV)
Length = 150
Score = 33.9 bits (74), Expect = 8.1
Identities = 21/66 (31%), Positives = 33/66 (50%), Gaps = 2/66 (3%)
Query: 227 LVLSNKVTGNVQDVANKYSKL--VTVICKYLRQNLEIDELKSNIKKLEISGTDLKVLNEI 284
L L + + NVQD N SKL V I K +QN++I E + ++K G D + +
Sbjct: 85 LTLYDIICDNVQDYINNSSKLKRVVKIYKCKKQNIKIKEARKSLKIATKRGVDYDYIKDS 144
Query: 285 KISNKK 290
+ N +
Sbjct: 145 CVLNSR 150
>UniRef50_Q7NB81 Cluster: Cell division protein ftsZ; n=1;
Mycoplasma gallisepticum|Rep: Cell division protein ftsZ
- Mycoplasma gallisepticum
Length = 462
Score = 33.9 bits (74), Expect = 8.1
Identities = 30/100 (30%), Positives = 49/100 (49%), Gaps = 8/100 (8%)
Query: 262 DELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLALEFS 321
D + N+ +++ TD K LN + + K + ++ T G G GG Q+ L S
Sbjct: 99 DLVSENLMFYQLN-TDSKHLNLLARNRSKAIRYLIDSPYT---DGHGAGGDVQKARLAIS 154
Query: 322 KYLHKVKDQ-LNDFDIFILSAGTDGIDGPTDAAGAIGYLN 360
+Y K D+ LN+ DI I+ A G+ T +AG+ +N
Sbjct: 155 QYFDKEVDEILNECDICIVIA---GLGKGTGSAGSTYIIN 191
>UniRef50_Q1U9U0 Cluster: Isochorismatase hydrolase; n=2;
Lactobacillus reuteri|Rep: Isochorismatase hydrolase -
Lactobacillus reuteri 100-23
Length = 167
Score = 33.9 bits (74), Expect = 8.1
Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Query: 324 LHKVKDQLNDFDIFILSAGTDG-IDGPTDAAGAIGYLNLISESTADGLDVDKYLANNDTY 382
L K+ + L ++ I A T+ +D A +GY ++ +T+ D +KY+ DT
Sbjct: 91 LEKILENLGINNLEICGAQTEYCVDATIKMAHGLGYQVIMQHNTSSTFD-NKYMTAEDTI 149
Query: 383 NFFK-LFKNDHLHVF 396
NFF+ ++ N L +F
Sbjct: 150 NFFENIWNNRFLTLF 164
>UniRef50_A0UW37 Cluster: Putative uncharacterized protein
precursor; n=1; Clostridium cellulolyticum H10|Rep:
Putative uncharacterized protein precursor - Clostridium
cellulolyticum H10
Length = 350
Score = 33.9 bits (74), Expect = 8.1
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 29 NKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPI 88
+K N YF K NL +NS Q + N I +L KD ++ +++ + LL S
Sbjct: 236 SKPENRWYFSDKKFNLTENSVQ---IYFINKIIELQKDKNIIFILNATNNKLLEDETSKQ 292
Query: 89 TLEEKIGLVKKLAN 102
++ I ++KL N
Sbjct: 293 GYQDNINAIEKLFN 306
>UniRef50_Q9C9Y9 Cluster: Putative uncharacterized protein
F17O14.14; n=2; core eudicotyledons|Rep: Putative
uncharacterized protein F17O14.14 - Arabidopsis thaliana
(Mouse-ear cress)
Length = 567
Score = 33.9 bits (74), Expect = 8.1
Identities = 39/146 (26%), Positives = 62/146 (42%), Gaps = 9/146 (6%)
Query: 24 SLDVFNKSRNVEYFEGAKDNLPDNSAQNTALKIKNLITQLNKDDLLLVLISGGGSA--LL 81
+LD+F+K R + + D LPD SA+ L + + I KDDLL G LL
Sbjct: 44 NLDLFSKIRR-SFPLASSDELPDVSAKLGRLSVGSKIAPKGKDDLLSSAEGGKNDYDWLL 102
Query: 82 PLPKSPITLEEKIGL-VKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILS 140
P +P+ + L K+A+S R +S + G + ++PA+ S+
Sbjct: 103 TPPGTPLGNDSHSSLAAPKIASSARASSASKASRLSVSQSESGYHS--SRPARSSSVTRP 160
Query: 141 DIVGDPLDLIASG---PTVQNTDGAN 163
I SG ++ NT A+
Sbjct: 161 SISTSQYSSFTSGRSPSSILNTSSAS 186
>UniRef50_Q551M7 Cluster: Putative uncharacterized protein; n=2;
Dictyostelium discoideum|Rep: Putative uncharacterized
protein - Dictyostelium discoideum AX4
Length = 716
Score = 33.9 bits (74), Expect = 8.1
Identities = 41/146 (28%), Positives = 69/146 (47%), Gaps = 15/146 (10%)
Query: 100 LANSGADIKELNTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDP---LDLIASGPTV 156
L N+G D +EL+T + + GG + +++ LS + DP LDLI+S TV
Sbjct: 20 LPNNGFDNEELDTADNLSGIVAGGVVGATTDGNLIMNEDLSQSITDPIKLLDLISSSETV 79
Query: 157 QNTDGANKAVD--VLKKYNLIDAL--PKSVQTLLENNGDNLVFPTNNTSNYIIGS--NKI 210
+ D A + + VL+ + L P++++ ++ LV P +IG+ N
Sbjct: 80 ER-DFAFRTISEFVLENESFTQELIKPENIRKII----TRLVEPDVQIRVSVIGTFRNLT 134
Query: 211 STKAAVVQ-CIELNYLPLVLSNKVTG 235
K + + I L+ L +LSN V G
Sbjct: 135 VVKEDICETLINLDILTPLLSNFVQG 160
>UniRef50_Q4UFK4 Cluster: Putative uncharacterized protein; n=1;
Theileria annulata|Rep: Putative uncharacterized protein
- Theileria annulata
Length = 1905
Score = 33.9 bits (74), Expect = 8.1
Identities = 48/224 (21%), Positives = 96/224 (42%), Gaps = 20/224 (8%)
Query: 74 SGGGSALLPLPKSPITLEEKIGLVKKLANSGADIKELNTVRKVISDLKGGQLAVKAQPAQ 133
+G G+ +P+ + + +I +V K SG + K+ NT+ D K P
Sbjct: 1232 TGKGANSMPMECTTEKIPNEIAVVTKTGESGNNSKDTNTMETPFGD-KEASFGAAVGPVT 1290
Query: 134 VVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLKKYNLIDALPKSVQTLLENNGDNL 193
V + +++ + +I G + K + ++ N I + ++ L N +NL
Sbjct: 1291 VTGDTIKELL---MKIILKGIII-------KEIIIINIDNKIKEINIPIKNKLINQKNNL 1340
Query: 194 VFPTNNTSNYIIGSNKI-STKAAVVQCIELNYLPLVLSNKVTGNVQDVANKYSKLVTV-- 250
N +N I K+ K ++ C+ + ++ +N N+Q K +KL
Sbjct: 1341 --DNENLNNLFINEIKLPKFKNKLLLCLYIISNDIISNNIKLFNIQLFQQKLNKLSNYKK 1398
Query: 251 ICKYLRQNLEIDE-LKSNIKK---LEISGTDLKVLNEIKISNKK 290
I + +N + +E L+ N+K LE+ ++L + I+N+K
Sbjct: 1399 INEINEKNEKNEELLEKNVKNEELLEMLEMSEELLEKKVINNEK 1442
>UniRef50_Q4U9U1 Cluster: Condensin subunit, putative; n=2;
Theileria|Rep: Condensin subunit, putative - Theileria
annulata
Length = 1724
Score = 33.9 bits (74), Expect = 8.1
Identities = 30/133 (22%), Positives = 56/133 (42%), Gaps = 7/133 (5%)
Query: 111 NTVRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDVLK 170
N V V+++ K + ++L ++G+ DL +V+ N+ +
Sbjct: 788 NVVESVLTEFKNVYFQTEDDTLTESCMLLIKLIGNT-DLTCLS-SVEKIFQINQTKQRIL 845
Query: 171 KYNLIDALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLS 230
NL+D +P + + TN N +I NK K + C LN + ++L+
Sbjct: 846 GLNLLDLIPTLISIATSTYSNTANSKTNPQDN-LIYRNKNLLKCKI--C--LNLIKIILA 900
Query: 231 NKVTGNVQDVANK 243
+ N+QD +NK
Sbjct: 901 SNQNSNIQDSSNK 913
>UniRef50_Q23MK9 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 414
Score = 33.9 bits (74), Expect = 8.1
Identities = 43/139 (30%), Positives = 62/139 (44%), Gaps = 16/139 (11%)
Query: 135 VSLILSDIVGDPLDLIASGPTVQNTDG-ANKAVDVLKKYNLIDAL---PKSVQTLLENNG 190
+ LIL+D P D G + N ++ +D+ K+NL D L P + +L N
Sbjct: 271 LKLILNDNNIGPQDTSGLGSILLNYPSLSHLKIDLKIKFNLRDKLNPLPSPLLNILFNAS 330
Query: 191 DNLVFPTNNTSNYIIGSNKI------STKAAVVQCIELNYLPLVLSNKVTGNVQDVANKY 244
L YII N+I S +A+++C +L+YL L LSN + + V
Sbjct: 331 QFLNVYLFILIKYIISKNQIGDEGVSSIGSALLKCTKLSYLNLKLSNNQIDD-EGVLGLG 389
Query: 245 SKLVTVICK---YLRQNLE 260
S L CK YL NLE
Sbjct: 390 SALAN--CKRLTYLELNLE 406
>UniRef50_A5KBR7 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 637
Score = 33.9 bits (74), Expect = 8.1
Identities = 37/145 (25%), Positives = 68/145 (46%), Gaps = 11/145 (7%)
Query: 155 TVQNTDGANKAVDVLK--KYNLIDALPKSVQTLLENN-GDNLVFPTNNTSNYIIGSNKIS 211
T T G ++D L +YN + A + + T+ E N + L + T S Y+ NK+
Sbjct: 39 TSSKTLGTGHSIDTLLDLRYNRLLARHELISTVDEENIKEQLGYNTQRKSVYLKSGNKLE 98
Query: 212 TKAAVVQCIELNYLPLV-----LSNKVTGNV--QDVANKYSKLVTVICKYLRQNLEIDEL 264
+AA ++ P L+ K G + ++ N K+ + + K +N + ++
Sbjct: 99 NEAAKRGKVKSGNSPKSENVKGLNLKFGGELKREEGRNGNLKIKSELKKEEEKNGNL-KI 157
Query: 265 KSNIKKLEISGTDLKVLNEIKISNK 289
KS +KK E +LK+ +E+K +K
Sbjct: 158 KSELKKEEEKNGNLKIKSELKSGSK 182
>UniRef50_A2FXH1 Cluster: Clan CA, family C19, ubiquitin
hydrolase-like cysteine peptidase; n=1; Trichomonas
vaginalis G3|Rep: Clan CA, family C19, ubiquitin
hydrolase-like cysteine peptidase - Trichomonas
vaginalis G3
Length = 2238
Score = 33.9 bits (74), Expect = 8.1
Identities = 29/134 (21%), Positives = 57/134 (42%), Gaps = 11/134 (8%)
Query: 204 IIGSNKISTKAAVVQCIELNYLPLVLSNKVTGNVQDVA-----NKYSKLVTVICKYLRQN 258
++ + I K + Q ++NY+ N+ + D A N +K V + YL N
Sbjct: 553 LLNYDVIKDKGPIEQIKDVNYIIRTAINEENSELLDTAAKLYQNDINKFVALTKDYLESN 612
Query: 259 LEIDELKSNIKKLEISGTDLKVLNEIKISNKKPLCLILGGEITVAVKGTGKGGRNQQLAL 318
+ + IKK+E+ D +V + + PL + + + +KGT G +++
Sbjct: 613 VVLQAYLGFIKKIELKHDD-EVYKITRNKHDSPLKMSI-----IEIKGTDLGKIKVPMSI 666
Query: 319 EFSKYLHKVKDQLN 332
+ K+ +LN
Sbjct: 667 TYEALREKIGYKLN 680
>UniRef50_A2EQ83 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 794
Score = 33.9 bits (74), Expect = 8.1
Identities = 49/216 (22%), Positives = 102/216 (47%), Gaps = 12/216 (5%)
Query: 59 LITQLNKDDLLLVLISGGGSALLPLPKSPITL--EEKIGLVKKL--ANSGADIKELNTVR 114
L T N D L V+ ++ + ++ I L EEK GL++ + S D +L ++
Sbjct: 377 LSTMFNNDSCLRVIFQCLNFIIVFVNRNKIGLSDEEKSGLLQLVEPVASLLDCNDLFIIK 436
Query: 115 KVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPT--VQNTDGANKAVD--VLK 170
++ L + + +++ LILS I+ D +L+++G T ++ +++D +
Sbjct: 437 ISLACLSYLSVFELSPRNEIMELILSKIICDD-ELVSNGATDALELFFDVTESIDCALAS 495
Query: 171 KYNLIDALPKSVQ--TLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLV 228
L+ A + Q T N D+++F T+ +I + A+++ IE +
Sbjct: 496 IPFLLQAYREKSQNETYYTNIADSIMFCAT-TAKVVIEDYAMDIIEALIEDIEQSDTIFE 554
Query: 229 LSNKVTGNVQDVANKYSKLVTVICKYLRQNLEIDEL 264
+ V+G V D++ +Y +++ I QN+E +E+
Sbjct: 555 VICYVSGFVNDISQEYLEILHNIFIISLQNIEDEEV 590
>UniRef50_Q2XW08 Cluster: Polyketide synthase 2; n=2; Cochliobolus
heterostrophus|Rep: Polyketide synthase 2 - Cochliobolus
heterostrophus (Drechslera maydis)
Length = 2144
Score = 33.9 bits (74), Expect = 8.1
Identities = 22/56 (39%), Positives = 30/56 (53%), Gaps = 9/56 (16%)
Query: 113 VRKVISDLKGGQLAVKAQPAQVVSLILSDIVGDPLDLIASGPTVQNTDGANKAVDV 168
++KV D KGG LAV A PA V+ L LD++ SG V + + K+V V
Sbjct: 661 IKKVQPDFKGGMLAVAAGPADVLPL---------LDIVTSGKVVIACENSPKSVTV 707
>UniRef50_Q6M0J7 Cluster: (2R)-phospho-3-sulfolactate synthase; n=5;
Methanococcus|Rep: (2R)-phospho-3-sulfolactate synthase
- Methanococcus maripaludis
Length = 235
Score = 33.9 bits (74), Expect = 8.1
Identities = 37/114 (32%), Positives = 56/114 (49%), Gaps = 12/114 (10%)
Query: 2 SRE-VENILQSKIKYGIISIPMGSL-DV-FNKSRNVEYFEGAKD------NLPDNSAQNT 52
SRE V+ +++ KYGI + P G+L +V F+K+ EY + KD + D S +
Sbjct: 37 SRELVKEKIENYKKYGIKTYPGGTLFEVCFSKNLFEEYLKECKDLGFECVEISDGSMELK 96
Query: 53 ALKIKNLITQLNKDDLLLVLISGGGSALLPLPKSPITLEEKIGLVKKLANSGAD 106
I Q K +++ G S +L S + + E+I LVKK SGAD
Sbjct: 97 PEDKDYAIKQAKKAGFIVLSEVGKKSIVLD---SELEIHERIELVKKDLESGAD 147
>UniRef50_Q9P6L5 Cluster: Endocytosis protein end4; n=1;
Schizosaccharomyces pombe|Rep: Endocytosis protein end4 -
Schizosaccharomyces pombe (Fission yeast)
Length = 1092
Score = 33.9 bits (74), Expect = 8.1
Identities = 26/90 (28%), Positives = 47/90 (52%), Gaps = 7/90 (7%)
Query: 177 ALPKSVQTLLENNGDNLVFPTNNTSNYIIGSNKISTKAAVVQCIELNYLPLVLSNKVTGN 236
A+ ++ TL+E D +V T++ + I+ N +S AA Q + + + ++KV +
Sbjct: 956 AVARATTTLIET-ADGVVNGTSSFEHLIVACNGVS--AATAQLVAASRVKANFASKVQDH 1012
Query: 237 VQDVANKYSKLVTVICKYLRQNLEIDELKS 266
++D A K VT CK L + +E LK+
Sbjct: 1013 LEDAA----KAVTEACKALVRQVESVALKA 1038
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.314 0.135 0.369
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 461,502,422
Number of Sequences: 1657284
Number of extensions: 20741501
Number of successful extensions: 53850
Number of sequences better than 10.0: 133
Number of HSP's better than 10.0 without gapping: 74
Number of HSP's successfully gapped in prelim test: 59
Number of HSP's that attempted gapping in prelim test: 53537
Number of HSP's gapped (non-prelim): 219
length of query: 421
length of database: 575,637,011
effective HSP length: 103
effective length of query: 318
effective length of database: 404,936,759
effective search space: 128769889362
effective search space used: 128769889362
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (21.9 bits)
S2: 74 (33.9 bits)
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