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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000826-TA|BGIBMGA000826-PA|IPR001156|Peptidase S60,
transferrin lactoferrin
         (855 letters)

Database: human 
           224,733 sequences; 73,234,838 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

M12154-1|AAA59992.1|  738|Homo sapiens melanotransferrin protein.     190   2e-47
BT007377-1|AAP36041.1|  302|Homo sapiens antigen p97 (melanoma a...   159   5e-38
BC111947-1|AAI11948.1|  302|Homo sapiens melanoma-associated ant...   159   5e-38
BC093920-1|AAH93920.1|  302|Homo sapiens antigen p97 (melanoma a...   159   5e-38
BC071910-1|AAH71910.1|  302|Homo sapiens antigen p97 (melanoma a...   159   5e-38
BC007550-1|AAH07550.1|  302|Homo sapiens antigen p97 (melanoma a...   159   5e-38
BC002623-1|AAH02623.1|  302|Homo sapiens antigen p97 (melanoma a...   159   5e-38
BC001875-1|AAH01875.1|  302|Homo sapiens antigen p97 (melanoma a...   159   5e-38
S95936-1|AAB22049.1|  698|Homo sapiens transferrin protein.           140   3e-32
M12530-1|AAA61140.1|  698|Homo sapiens TF protein.                    140   3e-32
DQ525716-1|ABF47110.1|  698|Homo sapiens transferrin protein.         140   3e-32
AY308797-1|AAP45055.1|  698|Homo sapiens transferrin protein.         140   3e-32
AF288144-1|AAK77664.1|  698|Homo sapiens transferin protein.          140   3e-32
DQ923758-1|ABI97197.1|  698|Homo sapiens transferrin protein.         139   3e-32
BC059367-1|AAH59367.1|  698|Homo sapiens transferrin protein.         139   4e-32
AK222755-1|BAD96475.1|  698|Homo sapiens transferrin variant pro...   139   4e-32
X52941-1|CAA37116.1|  709|Homo sapiens protein ( Human LTF mRNA ...   138   1e-31
U07643-1|AAB60324.1|  711|Homo sapiens lactoferrin protein.           138   1e-31
M93150-1|AAA36159.1|  711|Homo sapiens lactoferrin protein.           138   1e-31
M83205-1|AAA58656.1|  706|Homo sapiens HLF2 protein.                  138   1e-31
M83202-1|AAA59511.1|  711|Homo sapiens lactoferrin protein.           138   1e-31
M73700-1|AAA59479.1|  710|Homo sapiens neutrophil lactoferrin pr...   138   1e-31
DQ522304-1|ABF69105.1|  353|Homo sapiens lactoferrin protein.         138   1e-31
BC015823-1|AAH15823.1|  711|Homo sapiens lactotransferrin protein.    138   1e-31
BC015822-1|AAH15822.1|  711|Homo sapiens lactotransferrin protein.    138   1e-31
AY493417-1|AAS72878.1|  711|Homo sapiens growth-inhibiting prote...   138   1e-31
AY178998-1|AAN75578.2|  711|Homo sapiens lactoferrin protein.         138   1e-31
AY165046-1|AAN63998.1|  711|Homo sapiens lactotransferrin precur...   138   1e-31
AY137470-1|AAN11304.1|  711|Homo sapiens lactoferrin protein.         138   1e-31
AF332168-1|AAG48753.1|  711|Homo sapiens lactoferrin precursor p...   138   1e-31
AY875691-1|AAW71443.1|  711|Homo sapiens lactoferrin protein.         137   2e-31
AY360320-1|AAR12276.1|  709|Homo sapiens lactoferrin protein.         137   2e-31
X53961-1|CAA37914.1|  711|Homo sapiens precursor (AA -19 to 692)...   136   2e-31
BC022347-1|AAH22347.1|  711|Homo sapiens lactotransferrin protein.    136   4e-31
U95626-5|AAB57795.1|  475|Homo sapiens lactoferrin protein.           124   1e-27
AF508798-1|AAO14686.1|  234|Homo sapiens lactoferrin protein.         115   6e-25
M12525-1|AAA61142.1|  277|Homo sapiens TF protein.                    114   1e-24
M11372-1|AAA61141.1|  490|Homo sapiens TF protein.                    112   6e-24
M18642-1|AAA86665.1|  276|Homo sapiens lactoferrin protein.           103   2e-21
BC020671-1|AAH20671.1|  180|Homo sapiens Unknown (protein for IM...    91   2e-17
M17614-1|AAA61148.1|  135|Homo sapiens transferrin protein.            42   0.009
AF058327-1|AAC63506.1|   61|Homo sapiens transferrin protein.          42   0.009
U88581-1|AAB97880.1|   61|Homo sapiens transferrin protein.            39   0.086
DQ202398-1|ABA43715.1|  465|Homo sapiens ADAM21-like protein pro...    33   3.2  
BC109025-1|AAI09026.1|  721|Homo sapiens ADAM21 protein protein.       33   3.2  
BC109024-1|AAI09025.1|  722|Homo sapiens ADAM metallopeptidase d...    33   3.2  
AF158644-1|AAD55255.1|  722|Homo sapiens metalloproteinase-disin...    33   3.2  
AF029900-1|AAC52042.1|  542|Homo sapiens ADAM 21 protein.              33   3.2  

>M12154-1|AAA59992.1|  738|Homo sapiens melanotransferrin protein.
          Length = 738

 Score =  190 bits (463), Expect = 2e-47
 Identities = 119/356 (33%), Positives = 173/356 (48%), Gaps = 20/356 (5%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C TSDPE  KC  M  A + A + P L C R  S+ HC + IAA   D    D G +  A
Sbjct: 26  CATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEA 85

Query: 535 AQHDRLVPFMQEVYSS--GDSWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYP 592
            +   L P + EVY    G S YYAVAV +     T +  L+   +CHTGI    GW  P
Sbjct: 86  GKEHGLKPVVGEVYDQEVGTS-YYAVAVVRRSSHVT-IDTLKGVKSCHTGINRTVGWNVP 143

Query: 593 LAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGASFRR 652
           + YL+ +G +   GC+   A ++Y+  SC PGA  + Y +S       LC LC G S   
Sbjct: 144 VGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSES-------LCRLCRGDSSGE 196

Query: 653 --CRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAGRRREFWARXXXXXXXXXX 710
             C +   E+Y+ + GA RC+ EG GDVAFV+H+   E + G+    W +          
Sbjct: 197 GVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDGKTLPSWGQALLSQDFELL 256

Query: 711 XXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSFSM 770
              G+RA + E+R C+L +VP   ++ RA+ T+      L+    + +   + +  SF M
Sbjct: 257 CRDGSRADVTEWRQCHLARVPAHAVVVRAD-TDGGLIFRLLNEGQRLF---SHEGSSFQM 312

Query: 771 FYSQP-PYSDLIFSDVAVRLKPLPHNTRSAEIIAGPALLRAARIVSCDAPQASYYV 825
           F S+     DL+F D    L P+   T++ E   G   L A + + CD  +   Y+
Sbjct: 313 FSSEAYGQKDLLFKDSTSELVPIA--TQTYEAWLGHEYLHAMKGLLCDPNRLPPYL 366



 Score =  183 bits (446), Expect = 2e-45
 Identities = 129/391 (32%), Positives = 181/391 (46%), Gaps = 21/391 (5%)

Query: 414 FQLFSSNE--TTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAEKAVMGIRDCPVKR 471
           FQ+FSS      DLL +DST   + ++   Q  +  L ++Y+   A K ++   +     
Sbjct: 310 FQMFSSEAYGQKDLLFKDSTSELVPIAT--QTYEAWLGHEYL--HAMKGLLCDPNRLPPY 365

Query: 472 AALCVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDM 531
              CV S PE+ KC  M  A +   L PE+ C  A S +HC   I A   D       D+
Sbjct: 366 LRWCVLSTPEIQKCGDMAVAFRRQRLKPEIQCVSAKSPQHCMERIQAEQVDAVTLSGEDI 425

Query: 532 LHAAQHDRLVPFMQEVYSSGDSW--YYAVAVAKEQDPDT-DLTYLRAKNTCHTGIGMAAG 588
             A +   LVP   E Y+  DS   YY VAV +        L  LR K +CH G G  AG
Sbjct: 426 YTAGKKYGLVPAAGEHYAPEDSSNSYYVVAVVRRDSSHAFTLDELRGKRSCHAGFGSPAG 485

Query: 589 WLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGA 648
           W  P+  L+  G+IRP  C+   A +E++  SC P      Y  S       LC LC G 
Sbjct: 486 WDVPVGALIQRGFIRPKDCDVLTAVSEFFNASCVPVNNPKNYPSS-------LCALCVGD 538

Query: 649 SFRR--CRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAGRRREFWARXXXXXX 706
              R  C  ++ E+Y+G+ GA RC+VE  GDVAFVRHT   + + G   E WA       
Sbjct: 539 EQGRNKCVGNSQERYYGYRGAFRCLVENAGDVAFVRHTTVFDNTNGHNSEPWAAELRSED 598

Query: 707 XXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEF 766
                  G RA++ ++  CNL ++P   +M R + T +     L+  A   +G    ++ 
Sbjct: 599 YELLCPNGARAEVSQFAACNLAQIPPHAVMVRPD-TNIFTVYGLLDKAQDLFGD-DHNKN 656

Query: 767 SFSMFYSQPPY-SDLIFSDVAVRLKPLPHNT 796
            F MF S   +  DL+F D  VR  P+   T
Sbjct: 657 GFKMFDSSNYHGQDLLFKDATVRAVPVGEKT 687



 Score =  151 bits (366), Expect = 1e-35
 Identities = 101/324 (31%), Positives = 161/324 (49%), Gaps = 34/324 (10%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC  S  EQ KC   M  + ++ G+  +    L C +    + C++ +  +EA  + L
Sbjct: 23  VRWCATSDPEQHKCGN-MSEAFREAGIQPS----LLCVRGTSADHCVQLIAAQEADAITL 77

Query: 101 DAGEVYVAGRYHSLVPILQELDGR--GEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKAC 158
           D G +Y AG+ H L P++ E+  +  G  Y Y+VAVVR+     I        ++G K+C
Sbjct: 78  DGGAIYEAGKEHGLKPVVGEVYDQEVGTSY-YAVAVVRRSSHVTID------TLKGVKSC 130

Query: 159 FPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSD 218
              +    GW +P+  L++ G L V  C+  +K+ ++YFG SC P + +  Y      S+
Sbjct: 131 HTGINRTVGWNVPVGYLVESGRLSVMGCDV-LKAVSDYFGGSCVPGAGETSY------SE 183

Query: 219 KLCKLCYG---GAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
            LC+LC G   G G+ C  +  + +  Y GA +CL A  +GD+AFV+ +T+        +
Sbjct: 184 SLCRLCRGDSSGEGV-CDKSPLERYYDYSGAFRCL-AEGAGDVAFVKHSTVLENTDGKTL 241

Query: 274 LG---GITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQR 330
                 +    FEL+CRDGSR  VTEW  C+  +VPA A+V  +        R  N  QR
Sbjct: 242 PSWGQALLSQDFELLCRDGSRADVTEWRQCHLARVPAHAVVVRADTDGGLIFRLLNEGQR 301

Query: 331 IVQLYGEPNRFNKMYNATVYQPKD 354
              L+       +M+++  Y  KD
Sbjct: 302 ---LFSHEGSSFQMFSSEAYGQKD 322



 Score =  128 bits (309), Expect = 8e-29
 Identities = 95/327 (29%), Positives = 159/327 (48%), Gaps = 35/327 (10%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E +KC   M  + + + L      E+QC  A   + CM+ ++ E+   + L
Sbjct: 366 LRWCVLSTPEIQKCGD-MAVAFRRQRLKP----EIQCVSAKSPQHCMERIQAEQVDAVTL 420

Query: 101 DAGEVYVAGRYHSLVPILQEL---DGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKA 157
              ++Y AG+ + LVP   E    +     Y Y VAVVR+         + L  +RG ++
Sbjct: 421 SGEDIYTAGKKYGLVPAAGEHYAPEDSSNSY-YVVAVVRRDS----SHAFTLDELRGKRS 475

Query: 158 CFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNS 217
           C    GS AGW +P+  L+Q G ++  DC + + + +E+F  SC P     + NP  +  
Sbjct: 476 CHAGFGSPAGWDVPVGALIQRGFIRPKDC-DVLTAVSEFFNASCVP-----VNNP-KNYP 528

Query: 218 DKLCKLCYGGAGIR--C--TLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
             LC LC G    R  C     + + GY GA +CLV  N+GD+AFVR TT+      H  
Sbjct: 529 SSLCALCVGDEQGRNKCVGNSQERYYGYRGAFRCLV-ENAGDVAFVRHTTVFDNTNGHNS 587

Query: 274 ---LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQK-RRYQNFLQ 329
                 +  + +EL+C +G+R  V+++  CN  ++P  A++      P+         L 
Sbjct: 588 EPWAAELRSEDYELLCPNGARAEVSQFAACNLAQIPPHAVM----VRPDTNIFTVYGLLD 643

Query: 330 RIVQLYGEPNRFN--KMYNATVYQPKD 354
           +   L+G+ +  N  KM++++ Y  +D
Sbjct: 644 KAQDLFGDDHNKNGFKMFDSSNYHGQD 670


>BT007377-1|AAP36041.1|  302|Homo sapiens antigen p97 (melanoma
           associated) identified by monoclonal antibodies 133.2
           and protein.
          Length = 302

 Score =  159 bits (385), Expect = 5e-38
 Identities = 89/232 (38%), Positives = 120/232 (51%), Gaps = 15/232 (6%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C TSDPE  KC  M  A + A + P L C R  S+ HC + IAA   D    D G +  A
Sbjct: 26  CATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEA 85

Query: 535 AQHDRLVPFMQEVYSS--GDSWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYP 592
            +   L P + EVY    G S YYAVAV +     T +  L+   +CHTGI    GW  P
Sbjct: 86  GKEHGLKPVVGEVYDQEVGTS-YYAVAVVRRSSHVT-IDTLKGVKSCHTGINRTVGWNVP 143

Query: 593 LAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGASFRR 652
           + YL+ +G +   GC+   A ++Y+  SC PGA  + Y +S       LC LC G S   
Sbjct: 144 VGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSES-------LCRLCRGDSSGE 196

Query: 653 --CRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVS--AGRRREFWAR 700
             C +   E+Y+ + GA RC+ EG GDVAFV+H+   E +  +  RR+ W R
Sbjct: 197 GVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDESPSRRQTWTR 248



 Score =  115 bits (276), Expect = 8e-25
 Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 26/230 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC  S  EQ KC   M  + ++ G+  +    L C +    + C++ +  +EA  + L
Sbjct: 23  VRWCATSDPEQHKCGN-MSEAFREAGIQPS----LLCVRGTSADHCVQLIAAQEADAITL 77

Query: 101 DAGEVYVAGRYHSLVPILQEL-DGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACF 159
           D G +Y AG+ H L P++ E+ D       Y+VAVVR+     I        ++G K+C 
Sbjct: 78  DGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVTI------DTLKGVKSCH 131

Query: 160 PSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDK 219
             +    GW +P+  L++ G L V  C + +K+ ++YFG SC P + +  Y      S+ 
Sbjct: 132 TGINRTVGWNVPVGYLVESGRLSVMGC-DVLKAVSDYFGGSCVPGAGETSY------SES 184

Query: 220 LCKLCYG---GAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTI 264
           LC+LC G   G G+ C  +  + +  Y GA +CL A  +GD+AFV+ +T+
Sbjct: 185 LCRLCRGDSSGEGV-CDKSPLERYYDYSGAFRCL-AEGAGDVAFVKHSTV 232


>BC111947-1|AAI11948.1|  302|Homo sapiens melanoma-associated
           antigen p97, isoform 2, precursor protein.
          Length = 302

 Score =  159 bits (385), Expect = 5e-38
 Identities = 89/232 (38%), Positives = 120/232 (51%), Gaps = 15/232 (6%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C TSDPE  KC  M  A + A + P L C R  S+ HC + IAA   D    D G +  A
Sbjct: 26  CATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEA 85

Query: 535 AQHDRLVPFMQEVYSS--GDSWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYP 592
            +   L P + EVY    G S YYAVAV +     T +  L+   +CHTGI    GW  P
Sbjct: 86  GKEHGLKPVVGEVYDQEVGTS-YYAVAVVRRSSHVT-IDTLKGVKSCHTGINRTVGWNVP 143

Query: 593 LAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGASFRR 652
           + YL+ +G +   GC+   A ++Y+  SC PGA  + Y +S       LC LC G S   
Sbjct: 144 VGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSES-------LCRLCRGDSSGE 196

Query: 653 --CRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVS--AGRRREFWAR 700
             C +   E+Y+ + GA RC+ EG GDVAFV+H+   E +  +  RR+ W R
Sbjct: 197 GVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDESPSRRQTWTR 248



 Score =  115 bits (276), Expect = 8e-25
 Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 26/230 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC  S  EQ KC   M  + ++ G+  +    L C +    + C++ +  +EA  + L
Sbjct: 23  VRWCATSDPEQHKCGN-MSEAFREAGIQPS----LLCVRGTSADHCVQLIAAQEADAITL 77

Query: 101 DAGEVYVAGRYHSLVPILQEL-DGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACF 159
           D G +Y AG+ H L P++ E+ D       Y+VAVVR+     I        ++G K+C 
Sbjct: 78  DGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVTI------DTLKGVKSCH 131

Query: 160 PSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDK 219
             +    GW +P+  L++ G L V  C + +K+ ++YFG SC P + +  Y      S+ 
Sbjct: 132 TGINRTVGWNVPVGYLVESGRLSVMGC-DVLKAVSDYFGGSCVPGAGETSY------SES 184

Query: 220 LCKLCYG---GAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTI 264
           LC+LC G   G G+ C  +  + +  Y GA +CL A  +GD+AFV+ +T+
Sbjct: 185 LCRLCRGDSSGEGV-CDKSPLERYYDYSGAFRCL-AEGAGDVAFVKHSTV 232


>BC093920-1|AAH93920.1|  302|Homo sapiens antigen p97 (melanoma
           associated) identified by monoclonal antibodies 133.2
           and protein.
          Length = 302

 Score =  159 bits (385), Expect = 5e-38
 Identities = 89/232 (38%), Positives = 120/232 (51%), Gaps = 15/232 (6%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C TSDPE  KC  M  A + A + P L C R  S+ HC + IAA   D    D G +  A
Sbjct: 26  CATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEA 85

Query: 535 AQHDRLVPFMQEVYSS--GDSWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYP 592
            +   L P + EVY    G S YYAVAV +     T +  L+   +CHTGI    GW  P
Sbjct: 86  GKEHGLKPVVGEVYDQEVGTS-YYAVAVVRRSSHVT-IDTLKGVKSCHTGINRTVGWNVP 143

Query: 593 LAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGASFRR 652
           + YL+ +G +   GC+   A ++Y+  SC PGA  + Y +S       LC LC G S   
Sbjct: 144 VGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSES-------LCRLCRGDSSGE 196

Query: 653 --CRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVS--AGRRREFWAR 700
             C +   E+Y+ + GA RC+ EG GDVAFV+H+   E +  +  RR+ W R
Sbjct: 197 GVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDESPSRRQTWTR 248



 Score =  115 bits (276), Expect = 8e-25
 Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 26/230 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC  S  EQ KC   M  + ++ G+  +    L C +    + C++ +  +EA  + L
Sbjct: 23  VRWCATSDPEQHKCGN-MSEAFREAGIQPS----LLCVRGTSADHCVQLIAAQEADAITL 77

Query: 101 DAGEVYVAGRYHSLVPILQEL-DGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACF 159
           D G +Y AG+ H L P++ E+ D       Y+VAVVR+     I        ++G K+C 
Sbjct: 78  DGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVTI------DTLKGVKSCH 131

Query: 160 PSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDK 219
             +    GW +P+  L++ G L V  C + +K+ ++YFG SC P + +  Y      S+ 
Sbjct: 132 TGINRTVGWNVPVGYLVESGRLSVMGC-DVLKAVSDYFGGSCVPGAGETSY------SES 184

Query: 220 LCKLCYG---GAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTI 264
           LC+LC G   G G+ C  +  + +  Y GA +CL A  +GD+AFV+ +T+
Sbjct: 185 LCRLCRGDSSGEGV-CDKSPLERYYDYSGAFRCL-AEGAGDVAFVKHSTV 232


>BC071910-1|AAH71910.1|  302|Homo sapiens antigen p97 (melanoma
           associated) identified by monoclonal antibodies 133.2
           and protein.
          Length = 302

 Score =  159 bits (385), Expect = 5e-38
 Identities = 89/232 (38%), Positives = 120/232 (51%), Gaps = 15/232 (6%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C TSDPE  KC  M  A + A + P L C R  S+ HC + IAA   D    D G +  A
Sbjct: 26  CATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEA 85

Query: 535 AQHDRLVPFMQEVYSS--GDSWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYP 592
            +   L P + EVY    G S YYAVAV +     T +  L+   +CHTGI    GW  P
Sbjct: 86  GKEHGLKPVVGEVYDQEVGTS-YYAVAVVRRSSHVT-IDTLKGVKSCHTGINRTVGWNVP 143

Query: 593 LAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGASFRR 652
           + YL+ +G +   GC+   A ++Y+  SC PGA  + Y +S       LC LC G S   
Sbjct: 144 VGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSES-------LCRLCRGDSSGE 196

Query: 653 --CRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVS--AGRRREFWAR 700
             C +   E+Y+ + GA RC+ EG GDVAFV+H+   E +  +  RR+ W R
Sbjct: 197 GVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDESPSRRQTWTR 248



 Score =  115 bits (276), Expect = 8e-25
 Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 26/230 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC  S  EQ KC   M  + ++ G+  +    L C +    + C++ +  +EA  + L
Sbjct: 23  VRWCATSDPEQHKCGN-MSEAFREAGIQPS----LLCVRGTSADHCVQLIAAQEADAITL 77

Query: 101 DAGEVYVAGRYHSLVPILQEL-DGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACF 159
           D G +Y AG+ H L P++ E+ D       Y+VAVVR+     I        ++G K+C 
Sbjct: 78  DGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVTI------DTLKGVKSCH 131

Query: 160 PSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDK 219
             +    GW +P+  L++ G L V  C + +K+ ++YFG SC P + +  Y      S+ 
Sbjct: 132 TGINRTVGWNVPVGYLVESGRLSVMGC-DVLKAVSDYFGGSCVPGAGETSY------SES 184

Query: 220 LCKLCYG---GAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTI 264
           LC+LC G   G G+ C  +  + +  Y GA +CL A  +GD+AFV+ +T+
Sbjct: 185 LCRLCRGDSSGEGV-CDKSPLERYYDYSGAFRCL-AEGAGDVAFVKHSTV 232


>BC007550-1|AAH07550.1|  302|Homo sapiens antigen p97 (melanoma
           associated) identified by monoclonal antibodies 133.2
           and protein.
          Length = 302

 Score =  159 bits (385), Expect = 5e-38
 Identities = 89/232 (38%), Positives = 120/232 (51%), Gaps = 15/232 (6%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C TSDPE  KC  M  A + A + P L C R  S+ HC + IAA   D    D G +  A
Sbjct: 26  CATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEA 85

Query: 535 AQHDRLVPFMQEVYSS--GDSWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYP 592
            +   L P + EVY    G S YYAVAV +     T +  L+   +CHTGI    GW  P
Sbjct: 86  GKEHGLKPVVGEVYDQEVGTS-YYAVAVVRRSSHVT-IDTLKGVKSCHTGINRTVGWNVP 143

Query: 593 LAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGASFRR 652
           + YL+ +G +   GC+   A ++Y+  SC PGA  + Y +S       LC LC G S   
Sbjct: 144 VGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSES-------LCRLCRGDSSGE 196

Query: 653 --CRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVS--AGRRREFWAR 700
             C +   E+Y+ + GA RC+ EG GDVAFV+H+   E +  +  RR+ W R
Sbjct: 197 GVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDESPSRRQTWTR 248



 Score =  115 bits (276), Expect = 8e-25
 Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 26/230 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC  S  EQ KC   M  + ++ G+  +    L C +    + C++ +  +EA  + L
Sbjct: 23  VRWCATSDPEQHKCGN-MSEAFREAGIQPS----LLCVRGTSADHCVQLIAAQEADAITL 77

Query: 101 DAGEVYVAGRYHSLVPILQEL-DGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACF 159
           D G +Y AG+ H L P++ E+ D       Y+VAVVR+     I        ++G K+C 
Sbjct: 78  DGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVTI------DTLKGVKSCH 131

Query: 160 PSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDK 219
             +    GW +P+  L++ G L V  C + +K+ ++YFG SC P + +  Y      S+ 
Sbjct: 132 TGINRTVGWNVPVGYLVESGRLSVMGC-DVLKAVSDYFGGSCVPGAGETSY------SES 184

Query: 220 LCKLCYG---GAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTI 264
           LC+LC G   G G+ C  +  + +  Y GA +CL A  +GD+AFV+ +T+
Sbjct: 185 LCRLCRGDSSGEGV-CDKSPLERYYDYSGAFRCL-AEGAGDVAFVKHSTV 232


>BC002623-1|AAH02623.1|  302|Homo sapiens antigen p97 (melanoma
           associated) identified by monoclonal antibodies 133.2
           and protein.
          Length = 302

 Score =  159 bits (385), Expect = 5e-38
 Identities = 89/232 (38%), Positives = 120/232 (51%), Gaps = 15/232 (6%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C TSDPE  KC  M  A + A + P L C R  S+ HC + IAA   D    D G +  A
Sbjct: 26  CATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEA 85

Query: 535 AQHDRLVPFMQEVYSS--GDSWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYP 592
            +   L P + EVY    G S YYAVAV +     T +  L+   +CHTGI    GW  P
Sbjct: 86  GKEHGLKPVVGEVYDQEVGTS-YYAVAVVRRSSHVT-IDTLKGVKSCHTGINRTVGWNVP 143

Query: 593 LAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGASFRR 652
           + YL+ +G +   GC+   A ++Y+  SC PGA  + Y +S       LC LC G S   
Sbjct: 144 VGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSES-------LCRLCRGDSSGE 196

Query: 653 --CRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVS--AGRRREFWAR 700
             C +   E+Y+ + GA RC+ EG GDVAFV+H+   E +  +  RR+ W R
Sbjct: 197 GVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDESPSRRQTWTR 248



 Score =  115 bits (276), Expect = 8e-25
 Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 26/230 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC  S  EQ KC   M  + ++ G+  +    L C +    + C++ +  +EA  + L
Sbjct: 23  VRWCATSDPEQHKCGN-MSEAFREAGIQPS----LLCVRGTSADHCVQLIAAQEADAITL 77

Query: 101 DAGEVYVAGRYHSLVPILQEL-DGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACF 159
           D G +Y AG+ H L P++ E+ D       Y+VAVVR+     I        ++G K+C 
Sbjct: 78  DGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVTI------DTLKGVKSCH 131

Query: 160 PSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDK 219
             +    GW +P+  L++ G L V  C + +K+ ++YFG SC P + +  Y      S+ 
Sbjct: 132 TGINRTVGWNVPVGYLVESGRLSVMGC-DVLKAVSDYFGGSCVPGAGETSY------SES 184

Query: 220 LCKLCYG---GAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTI 264
           LC+LC G   G G+ C  +  + +  Y GA +CL A  +GD+AFV+ +T+
Sbjct: 185 LCRLCRGDSSGEGV-CDKSPLERYYDYSGAFRCL-AEGAGDVAFVKHSTV 232


>BC001875-1|AAH01875.1|  302|Homo sapiens antigen p97 (melanoma
           associated) identified by monoclonal antibodies 133.2
           and protein.
          Length = 302

 Score =  159 bits (385), Expect = 5e-38
 Identities = 89/232 (38%), Positives = 120/232 (51%), Gaps = 15/232 (6%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C TSDPE  KC  M  A + A + P L C R  S+ HC + IAA   D    D G +  A
Sbjct: 26  CATSDPEQHKCGNMSEAFREAGIQPSLLCVRGTSADHCVQLIAAQEADAITLDGGAIYEA 85

Query: 535 AQHDRLVPFMQEVYSS--GDSWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYP 592
            +   L P + EVY    G S YYAVAV +     T +  L+   +CHTGI    GW  P
Sbjct: 86  GKEHGLKPVVGEVYDQEVGTS-YYAVAVVRRSSHVT-IDTLKGVKSCHTGINRTVGWNVP 143

Query: 593 LAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGASFRR 652
           + YL+ +G +   GC+   A ++Y+  SC PGA  + Y +S       LC LC G S   
Sbjct: 144 VGYLVESGRLSVMGCDVLKAVSDYFGGSCVPGAGETSYSES-------LCRLCRGDSSGE 196

Query: 653 --CRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVS--AGRRREFWAR 700
             C +   E+Y+ + GA RC+ EG GDVAFV+H+   E +  +  RR+ W R
Sbjct: 197 GVCDKSPLERYYDYSGAFRCLAEGAGDVAFVKHSTVLENTDESPSRRQTWTR 248



 Score =  115 bits (276), Expect = 8e-25
 Identities = 72/230 (31%), Positives = 119/230 (51%), Gaps = 26/230 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC  S  EQ KC   M  + ++ G+  +    L C +    + C++ +  +EA  + L
Sbjct: 23  VRWCATSDPEQHKCGN-MSEAFREAGIQPS----LLCVRGTSADHCVQLIAAQEADAITL 77

Query: 101 DAGEVYVAGRYHSLVPILQEL-DGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACF 159
           D G +Y AG+ H L P++ E+ D       Y+VAVVR+     I        ++G K+C 
Sbjct: 78  DGGAIYEAGKEHGLKPVVGEVYDQEVGTSYYAVAVVRRSSHVTI------DTLKGVKSCH 131

Query: 160 PSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDK 219
             +    GW +P+  L++ G L V  C + +K+ ++YFG SC P + +  Y      S+ 
Sbjct: 132 TGINRTVGWNVPVGYLVESGRLSVMGC-DVLKAVSDYFGGSCVPGAGETSY------SES 184

Query: 220 LCKLCYG---GAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTI 264
           LC+LC G   G G+ C  +  + +  Y GA +CL A  +GD+AFV+ +T+
Sbjct: 185 LCRLCRGDSSGEGV-CDKSPLERYYDYSGAFRCL-AEGAGDVAFVKHSTV 232


>S95936-1|AAB22049.1|  698|Homo sapiens transferrin protein.
          Length = 698

 Score =  140 bits (338), Expect = 3e-32
 Identities = 108/334 (32%), Positives = 153/334 (45%), Gaps = 34/334 (10%)

Query: 460 AVMGI-RDCPVKRAALCVTSDPEMDKCVKMRRALKAA--SLSPELSCWRAHSSRHCARAI 516
           AV+G+    P K    C  S+ E  KC   R  +K+   S  P ++C +  S   C RAI
Sbjct: 12  AVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAI 71

Query: 517 AAGSCDFALFDAGDMLHA-AQHDRLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTY 572
           AA   D    DAG +  A    + L P + E Y S +   ++YYAVAV K+ D    +  
Sbjct: 72  AANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQ 130

Query: 573 LRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVD 632
           LR K +CHTG+G +AGW  P+  L  +  +         A A +++ SCAP A      D
Sbjct: 131 LRGKKSCHTGLGRSAGWNIPIGLLYCD--LPEPRKPLEKAVANFFSGSCAPCA------D 182

Query: 633 SGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAG 692
               P   LC LC G     C      QYFG+ GA +C+ +G GDVAFV+H+   E  A 
Sbjct: 183 GTDFP--QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLAN 235

Query: 693 RRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMV 752
           +                     TR  + EY+ C+L +VP   ++ R+   + D    L+ 
Sbjct: 236 K--------ADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLN 287

Query: 753 YALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVA 786
            A + +G   S EF     +S P   DL+F D A
Sbjct: 288 QAQEHFGKDKSKEF---QLFSSPHGKDLLFKDSA 318



 Score =  138 bits (333), Expect = 1e-31
 Identities = 121/425 (28%), Positives = 183/425 (43%), Gaps = 50/425 (11%)

Query: 401 QRTDDTGRPIELPFQLFSSNETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAEKA 460
           Q  +  G+     FQLFSS    DLL +DS   F+ +     A        Y+G +   A
Sbjct: 288 QAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDA------KMYLGYEYVTA 341

Query: 461 VMGIRD--CP------VKRAALCVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
           +  +R+  CP       K    C  S  E  KC +      + +   ++ C  A ++  C
Sbjct: 342 IRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEW-----SVNSVGKIECVSAETTEDC 396

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDSW-------YYAVAVAKEQD 565
              I  G  D    D G  ++ A    LVP + E Y+  D+        Y+AVAV K+  
Sbjct: 397 IAKIMNGEADAMSLDGG-FVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA 455

Query: 566 PDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGA 625
            D     L+ K +CHT +G  AGW  P+  L +    +   C       E++++ CAPG+
Sbjct: 456 SDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYN----KINHCR----FDEFFSEGCAPGS 507

Query: 626 LSSEYVDSGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTA 685
                 DS      +LC LC G+    C  +  E Y+G+ GA RC+VE  GDVAFV+H  
Sbjct: 508 KK----DS------SLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVE-KGDVAFVKHQT 556

Query: 686 PAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELD 745
             + + G+  + WA+             GTR  + EY +C+L + P   ++ R +  E  
Sbjct: 557 VPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKD-KEAC 615

Query: 746 AFSNLMVYALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNTRSAEIIAGP 805
               L      F   VT    +F +F S+    DL+F D  V L  L H+  + E   G 
Sbjct: 616 VHKILRQQQHLFGSNVTDCSGNFCLFRSET--KDLLFRDDTVCLAKL-HDRNTYEKYLGE 672

Query: 806 ALLRA 810
             ++A
Sbjct: 673 EYVKA 677



 Score =  124 bits (298), Expect = 2e-27
 Identities = 88/284 (30%), Positives = 141/284 (49%), Gaps = 34/284 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC+         K +  +D   + C K     +C++ +   EA  + L
Sbjct: 25  VRWCAVSEHEATKCQSFRDHM---KSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTL 81

Query: 101 DAGEVYVAGRY-HSLVPILQELDGRGEPYQ---YSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           DAG VY A    ++L P++ E  G  E  Q   Y+VAVV+K        G+ +  +RG K
Sbjct: 82  DAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDS------GFQMNQLRGKK 135

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHV-KSATEYFGESCAPNSLKDLYNPIGD 215
           +C   +G  AGW +PI +L  +    + +    + K+   +F  SCAP +        G 
Sbjct: 136 SCHTGLGRSAGWNIPIGLLYCD----LPEPRKPLEKAVANFFSGSCAPCA-------DGT 184

Query: 216 NSDKLCKLCYGGAGIRCTLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILG 275
           +  +LC+LC    G  C+  + + GY GA KCL  + +GD+AFV+ +TI   L +     
Sbjct: 185 DFPQLCQLC---PGCGCSTLNQYFGYSGAFKCL-KDGAGDVAFVKHSTIFENLANKA--- 237

Query: 276 GITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPE 319
               DQ+EL+C D +R+PV E++ C+  +VP+  +V  S    E
Sbjct: 238 --DRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKE 279



 Score =  117 bits (281), Expect = 2e-25
 Identities = 87/284 (30%), Positives = 133/284 (46%), Gaps = 48/284 (16%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E+ KC++   +S+           +++C  A   E+C+  +   EA  + L
Sbjct: 361 VKWCALSHHERLKCDEWSVNSVG----------KIECVSAETTEDCIAKIMNGEADAMSL 410

Query: 101 DAGEVYVAGRYHSLVPILQE-------LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMR 153
           D G VY+AG+   LVP+L E        +   E   ++VAVV+K              ++
Sbjct: 411 DGGFVYIAGKC-GLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA-----SDLTWDNLK 464

Query: 154 GAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPI 213
           G K+C  +VG  AGW +P+ +L      K+  C        E+F E CAP S KD     
Sbjct: 465 GKKSCHTAVGRTAGWNIPMGLLYN----KINHCR-----FDEFFSEGCAPGSKKD----- 510

Query: 214 GDNSDKLCKLCYGGAGIRC--TLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSH 271
                 LCKLC G     C     + + GY GA +CLV    GD+AFV+  T+       
Sbjct: 511 ----SSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLV--EKGDVAFVKHQTVPQNTGGK 564

Query: 272 KI---LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
                   + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 565 NPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 608


>M12530-1|AAA61140.1|  698|Homo sapiens TF protein.
          Length = 698

 Score =  140 bits (338), Expect = 3e-32
 Identities = 108/334 (32%), Positives = 153/334 (45%), Gaps = 34/334 (10%)

Query: 460 AVMGI-RDCPVKRAALCVTSDPEMDKCVKMRRALKAA--SLSPELSCWRAHSSRHCARAI 516
           AV+G+    P K    C  S+ E  KC   R  +K+   S  P ++C +  S   C RAI
Sbjct: 12  AVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAI 71

Query: 517 AAGSCDFALFDAGDMLHA-AQHDRLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTY 572
           AA   D    DAG +  A    + L P + E Y S +   ++YYAVAV K+ D    +  
Sbjct: 72  AANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQ 130

Query: 573 LRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVD 632
           LR K +CHTG+G +AGW  P+  L  +  +         A A +++ SCAP A      D
Sbjct: 131 LRGKKSCHTGLGRSAGWNIPIGLLYCD--LPEPRKPLEKAVANFFSGSCAPCA------D 182

Query: 633 SGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAG 692
               P   LC LC G     C      QYFG+ GA +C+ +G GDVAFV+H+   E  A 
Sbjct: 183 GTDFP--QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLAN 235

Query: 693 RRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMV 752
           +                     TR  + EY+ C+L +VP   ++ R+   + D    L+ 
Sbjct: 236 K--------ADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLN 287

Query: 753 YALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVA 786
            A + +G   S EF     +S P   DL+F D A
Sbjct: 288 QAQEHFGKDKSKEF---QLFSSPHGKDLLFKDSA 318



 Score =  138 bits (333), Expect = 1e-31
 Identities = 121/425 (28%), Positives = 183/425 (43%), Gaps = 50/425 (11%)

Query: 401 QRTDDTGRPIELPFQLFSSNETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAEKA 460
           Q  +  G+     FQLFSS    DLL +DS   F+ +     A        Y+G +   A
Sbjct: 288 QAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDA------KMYLGYEYVTA 341

Query: 461 VMGIRD--CP------VKRAALCVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
           +  +R+  CP       K    C  S  E  KC +      + +   ++ C  A ++  C
Sbjct: 342 IRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEW-----SVNSVGKIECVSAETTEDC 396

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDSW-------YYAVAVAKEQD 565
              I  G  D    D G  ++ A    LVP + E Y+  D+        Y+AVAV K+  
Sbjct: 397 IAKIMNGEADAMSLDGG-FVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA 455

Query: 566 PDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGA 625
            D     L+ K +CHT +G  AGW  P+  L +    +   C       E++++ CAPG+
Sbjct: 456 SDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYN----KINHCR----FDEFFSEGCAPGS 507

Query: 626 LSSEYVDSGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTA 685
                 DS      +LC LC G+    C  +  E Y+G+ GA RC+VE  GDVAFV+H  
Sbjct: 508 KK----DS------SLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVE-KGDVAFVKHQT 556

Query: 686 PAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELD 745
             + + G+  + WA+             GTR  + EY +C+L + P   ++ R +  E  
Sbjct: 557 VPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKD-KEAC 615

Query: 746 AFSNLMVYALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNTRSAEIIAGP 805
               L      F   VT    +F +F S+    DL+F D  V L  L H+  + E   G 
Sbjct: 616 VHKILRQQQHLFGSNVTDCSGNFCLFRSET--KDLLFRDDTVCLAKL-HDRNTYEKYLGE 672

Query: 806 ALLRA 810
             ++A
Sbjct: 673 EYVKA 677



 Score =  124 bits (298), Expect = 2e-27
 Identities = 88/284 (30%), Positives = 141/284 (49%), Gaps = 34/284 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC+         K +  +D   + C K     +C++ +   EA  + L
Sbjct: 25  VRWCAVSEHEATKCQSFRDHM---KSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTL 81

Query: 101 DAGEVYVAGRY-HSLVPILQELDGRGEPYQ---YSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           DAG VY A    ++L P++ E  G  E  Q   Y+VAVV+K        G+ +  +RG K
Sbjct: 82  DAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDS------GFQMNQLRGKK 135

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHV-KSATEYFGESCAPNSLKDLYNPIGD 215
           +C   +G  AGW +PI +L  +    + +    + K+   +F  SCAP +        G 
Sbjct: 136 SCHTGLGRSAGWNIPIGLLYCD----LPEPRKPLEKAVANFFSGSCAPCA-------DGT 184

Query: 216 NSDKLCKLCYGGAGIRCTLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILG 275
           +  +LC+LC    G  C+  + + GY GA KCL  + +GD+AFV+ +TI   L +     
Sbjct: 185 DFPQLCQLC---PGCGCSTLNQYFGYSGAFKCL-KDGAGDVAFVKHSTIFENLANKA--- 237

Query: 276 GITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPE 319
               DQ+EL+C D +R+PV E++ C+  +VP+  +V  S    E
Sbjct: 238 --DRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKE 279



 Score =  117 bits (281), Expect = 2e-25
 Identities = 87/284 (30%), Positives = 133/284 (46%), Gaps = 48/284 (16%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E+ KC++   +S+           +++C  A   E+C+  +   EA  + L
Sbjct: 361 VKWCALSHHERLKCDEWSVNSVG----------KIECVSAETTEDCIAKIMNGEADAMSL 410

Query: 101 DAGEVYVAGRYHSLVPILQE-------LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMR 153
           D G VY+AG+   LVP+L E        +   E   ++VAVV+K              ++
Sbjct: 411 DGGFVYIAGKC-GLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA-----SDLTWDNLK 464

Query: 154 GAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPI 213
           G K+C  +VG  AGW +P+ +L      K+  C        E+F E CAP S KD     
Sbjct: 465 GKKSCHTAVGRTAGWNIPMGLLYN----KINHCR-----FDEFFSEGCAPGSKKD----- 510

Query: 214 GDNSDKLCKLCYGGAGIRC--TLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSH 271
                 LCKLC G     C     + + GY GA +CLV    GD+AFV+  T+       
Sbjct: 511 ----SSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLV--EKGDVAFVKHQTVPQNTGGK 564

Query: 272 KI---LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
                   + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 565 NPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 608


>DQ525716-1|ABF47110.1|  698|Homo sapiens transferrin protein.
          Length = 698

 Score =  140 bits (338), Expect = 3e-32
 Identities = 108/334 (32%), Positives = 153/334 (45%), Gaps = 34/334 (10%)

Query: 460 AVMGI-RDCPVKRAALCVTSDPEMDKCVKMRRALKAA--SLSPELSCWRAHSSRHCARAI 516
           AV+G+    P K    C  S+ E  KC   R  +K+   S  P ++C +  S   C RAI
Sbjct: 12  AVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAI 71

Query: 517 AAGSCDFALFDAGDMLHA-AQHDRLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTY 572
           AA   D    DAG +  A    + L P + E Y S +   ++YYAVAV K+ D    +  
Sbjct: 72  AANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQ 130

Query: 573 LRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVD 632
           LR K +CHTG+G +AGW  P+  L  +  +         A A +++ SCAP A      D
Sbjct: 131 LRGKKSCHTGLGRSAGWNIPIGLLYCD--LPEPRKPLEKAVANFFSGSCAPCA------D 182

Query: 633 SGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAG 692
               P   LC LC G     C      QYFG+ GA +C+ +G GDVAFV+H+   E  A 
Sbjct: 183 GTDFP--QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLAN 235

Query: 693 RRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMV 752
           +                     TR  + EY+ C+L +VP   ++ R+   + D    L+ 
Sbjct: 236 K--------ADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLN 287

Query: 753 YALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVA 786
            A + +G   S EF     +S P   DL+F D A
Sbjct: 288 QAQEHFGKDKSKEF---QLFSSPHGKDLLFKDSA 318



 Score =  138 bits (333), Expect = 1e-31
 Identities = 121/425 (28%), Positives = 183/425 (43%), Gaps = 50/425 (11%)

Query: 401 QRTDDTGRPIELPFQLFSSNETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAEKA 460
           Q  +  G+     FQLFSS    DLL +DS   F+ +     A        Y+G +   A
Sbjct: 288 QAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDA------KMYLGYEYVTA 341

Query: 461 VMGIRD--CP------VKRAALCVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
           +  +R+  CP       K    C  S  E  KC +      + +   ++ C  A ++  C
Sbjct: 342 IRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEW-----SVNSVGKIECVSAETTEDC 396

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDSW-------YYAVAVAKEQD 565
              I  G  D    D G  ++ A    LVP + E Y+  D+        Y+AVAV K+  
Sbjct: 397 IAKIMNGEADAMSLDGG-FVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA 455

Query: 566 PDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGA 625
            D     L+ K +CHT +G  AGW  P+  L +    +   C       E++++ CAPG+
Sbjct: 456 SDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYN----KINHCR----FDEFFSEGCAPGS 507

Query: 626 LSSEYVDSGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTA 685
                 DS      +LC LC G+    C  +  E Y+G+ GA RC+VE  GDVAFV+H  
Sbjct: 508 KK----DS------SLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVE-KGDVAFVKHQT 556

Query: 686 PAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELD 745
             + + G+  + WA+             GTR  + EY +C+L + P   ++ R +  E  
Sbjct: 557 VPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKD-KEAC 615

Query: 746 AFSNLMVYALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNTRSAEIIAGP 805
               L      F   VT    +F +F S+    DL+F D  V L  L H+  + E   G 
Sbjct: 616 VHKILRQQQHLFGSNVTDCSGNFCLFRSET--KDLLFRDDTVCLAKL-HDRNTYEKYLGE 672

Query: 806 ALLRA 810
             ++A
Sbjct: 673 EYVKA 677



 Score =  124 bits (298), Expect = 2e-27
 Identities = 88/284 (30%), Positives = 141/284 (49%), Gaps = 34/284 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC+         K +  +D   + C K     +C++ +   EA  + L
Sbjct: 25  VRWCAVSEHEATKCQSFRDHM---KSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTL 81

Query: 101 DAGEVYVAGRY-HSLVPILQELDGRGEPYQ---YSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           DAG VY A    ++L P++ E  G  E  Q   Y+VAVV+K        G+ +  +RG K
Sbjct: 82  DAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDS------GFQMNQLRGKK 135

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHV-KSATEYFGESCAPNSLKDLYNPIGD 215
           +C   +G  AGW +PI +L  +    + +    + K+   +F  SCAP +        G 
Sbjct: 136 SCHTGLGRSAGWNIPIGLLYCD----LPEPRKPLEKAVANFFSGSCAPCA-------DGT 184

Query: 216 NSDKLCKLCYGGAGIRCTLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILG 275
           +  +LC+LC    G  C+  + + GY GA KCL  + +GD+AFV+ +TI   L +     
Sbjct: 185 DFPQLCQLC---PGCGCSTLNQYFGYSGAFKCL-KDGAGDVAFVKHSTIFENLANKA--- 237

Query: 276 GITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPE 319
               DQ+EL+C D +R+PV E++ C+  +VP+  +V  S    E
Sbjct: 238 --DRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKE 279



 Score =  117 bits (281), Expect = 2e-25
 Identities = 87/284 (30%), Positives = 133/284 (46%), Gaps = 48/284 (16%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E+ KC++   +S+           +++C  A   E+C+  +   EA  + L
Sbjct: 361 VKWCALSHHERLKCDEWSVNSVG----------KIECVSAETTEDCIAKIMNGEADAMSL 410

Query: 101 DAGEVYVAGRYHSLVPILQE-------LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMR 153
           D G VY+AG+   LVP+L E        +   E   ++VAVV+K              ++
Sbjct: 411 DGGFVYIAGKC-GLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA-----SDLTWDNLK 464

Query: 154 GAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPI 213
           G K+C  +VG  AGW +P+ +L      K+  C        E+F E CAP S KD     
Sbjct: 465 GKKSCHTAVGRTAGWNIPMGLLYN----KINHCR-----FDEFFSEGCAPGSKKD----- 510

Query: 214 GDNSDKLCKLCYGGAGIRC--TLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSH 271
                 LCKLC G     C     + + GY GA +CLV    GD+AFV+  T+       
Sbjct: 511 ----SSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLV--EKGDVAFVKHQTVPQNTGGK 564

Query: 272 KI---LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
                   + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 565 NPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 608


>AY308797-1|AAP45055.1|  698|Homo sapiens transferrin protein.
          Length = 698

 Score =  140 bits (338), Expect = 3e-32
 Identities = 108/334 (32%), Positives = 153/334 (45%), Gaps = 34/334 (10%)

Query: 460 AVMGI-RDCPVKRAALCVTSDPEMDKCVKMRRALKAA--SLSPELSCWRAHSSRHCARAI 516
           AV+G+    P K    C  S+ E  KC   R  +K+   S  P ++C +  S   C RAI
Sbjct: 12  AVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAI 71

Query: 517 AAGSCDFALFDAGDMLHA-AQHDRLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTY 572
           AA   D    DAG +  A    + L P + E Y S +   ++YYAVAV K+ D    +  
Sbjct: 72  AANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQ 130

Query: 573 LRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVD 632
           LR K +CHTG+G +AGW  P+  L  +  +         A A +++ SCAP A      D
Sbjct: 131 LRGKKSCHTGLGRSAGWNIPIGLLYCD--LPEPRKPLEKAVANFFSGSCAPCA------D 182

Query: 633 SGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAG 692
               P   LC LC G     C      QYFG+ GA +C+ +G GDVAFV+H+   E  A 
Sbjct: 183 GTDFP--QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLAN 235

Query: 693 RRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMV 752
           +                     TR  + EY+ C+L +VP   ++ R+   + D    L+ 
Sbjct: 236 K--------ADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLN 287

Query: 753 YALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVA 786
            A + +G   S EF     +S P   DL+F D A
Sbjct: 288 QAQEHFGKDKSKEF---QLFSSPHGKDLLFKDSA 318



 Score =  138 bits (333), Expect = 1e-31
 Identities = 121/425 (28%), Positives = 183/425 (43%), Gaps = 50/425 (11%)

Query: 401 QRTDDTGRPIELPFQLFSSNETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAEKA 460
           Q  +  G+     FQLFSS    DLL +DS   F+ +     A        Y+G +   A
Sbjct: 288 QAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDA------KMYLGYEYVTA 341

Query: 461 VMGIRD--CP------VKRAALCVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
           +  +R+  CP       K    C  S  E  KC +      + +   ++ C  A ++  C
Sbjct: 342 IRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEW-----SVNSVGKIECVSAETTEDC 396

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDSW-------YYAVAVAKEQD 565
              I  G  D    D G  ++ A    LVP + E Y+  D+        Y+AVAV K+  
Sbjct: 397 IAKIMNGEADAMSLDGG-FVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA 455

Query: 566 PDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGA 625
            D     L+ K +CHT +G  AGW  P+  L +    +   C       E++++ CAPG+
Sbjct: 456 SDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYN----KINHCR----FDEFFSEGCAPGS 507

Query: 626 LSSEYVDSGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTA 685
                 DS      +LC LC G+    C  +  E Y+G+ GA RC+VE  GDVAFV+H  
Sbjct: 508 KK----DS------SLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVE-KGDVAFVKHQT 556

Query: 686 PAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELD 745
             + + G+  + WA+             GTR  + EY +C+L + P   ++ R +  E  
Sbjct: 557 VPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKD-KEAC 615

Query: 746 AFSNLMVYALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNTRSAEIIAGP 805
               L      F   VT    +F +F S+    DL+F D  V L  L H+  + E   G 
Sbjct: 616 VHKILRQQQHLFGSNVTDCSGNFCLFRSET--KDLLFRDDTVCLAKL-HDRNTYEKYLGE 672

Query: 806 ALLRA 810
             ++A
Sbjct: 673 EYVKA 677



 Score =  124 bits (298), Expect = 2e-27
 Identities = 88/284 (30%), Positives = 141/284 (49%), Gaps = 34/284 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC+         K +  +D   + C K     +C++ +   EA  + L
Sbjct: 25  VRWCAVSEHEATKCQSFRDHM---KSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTL 81

Query: 101 DAGEVYVAGRY-HSLVPILQELDGRGEPYQ---YSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           DAG VY A    ++L P++ E  G  E  Q   Y+VAVV+K        G+ +  +RG K
Sbjct: 82  DAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDS------GFQMNQLRGKK 135

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHV-KSATEYFGESCAPNSLKDLYNPIGD 215
           +C   +G  AGW +PI +L  +    + +    + K+   +F  SCAP +        G 
Sbjct: 136 SCHTGLGRSAGWNIPIGLLYCD----LPEPRKPLEKAVANFFSGSCAPCA-------DGT 184

Query: 216 NSDKLCKLCYGGAGIRCTLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILG 275
           +  +LC+LC    G  C+  + + GY GA KCL  + +GD+AFV+ +TI   L +     
Sbjct: 185 DFPQLCQLC---PGCGCSTLNQYFGYSGAFKCL-KDGAGDVAFVKHSTIFENLANKA--- 237

Query: 276 GITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPE 319
               DQ+EL+C D +R+PV E++ C+  +VP+  +V  S    E
Sbjct: 238 --DRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKE 279



 Score =  117 bits (281), Expect = 2e-25
 Identities = 87/284 (30%), Positives = 133/284 (46%), Gaps = 48/284 (16%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E+ KC++   +S+           +++C  A   E+C+  +   EA  + L
Sbjct: 361 VKWCALSHHERLKCDEWSVNSVG----------KIECVSAETTEDCIAKIMNGEADAMSL 410

Query: 101 DAGEVYVAGRYHSLVPILQE-------LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMR 153
           D G VY+AG+   LVP+L E        +   E   ++VAVV+K              ++
Sbjct: 411 DGGFVYIAGKC-GLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA-----SDLTWDNLK 464

Query: 154 GAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPI 213
           G K+C  +VG  AGW +P+ +L      K+  C        E+F E CAP S KD     
Sbjct: 465 GKKSCHTAVGRTAGWNIPMGLLYN----KINHCR-----FDEFFSEGCAPGSKKD----- 510

Query: 214 GDNSDKLCKLCYGGAGIRC--TLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSH 271
                 LCKLC G     C     + + GY GA +CLV    GD+AFV+  T+       
Sbjct: 511 ----SSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLV--EKGDVAFVKHQTVPQNTGGK 564

Query: 272 KI---LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
                   + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 565 NPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 608


>AF288144-1|AAK77664.1|  698|Homo sapiens transferin protein.
          Length = 698

 Score =  140 bits (338), Expect = 3e-32
 Identities = 108/334 (32%), Positives = 153/334 (45%), Gaps = 34/334 (10%)

Query: 460 AVMGI-RDCPVKRAALCVTSDPEMDKCVKMRRALKAA--SLSPELSCWRAHSSRHCARAI 516
           AV+G+    P K    C  S+ E  KC   R  +K+   S  P ++C +  S   C RAI
Sbjct: 12  AVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAI 71

Query: 517 AAGSCDFALFDAGDMLHA-AQHDRLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTY 572
           AA   D    DAG +  A    + L P + E Y S +   ++YYAVAV K+ D    +  
Sbjct: 72  AANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQ 130

Query: 573 LRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVD 632
           LR K +CHTG+G +AGW  P+  L  +  +         A A +++ SCAP A      D
Sbjct: 131 LRGKKSCHTGLGRSAGWNIPIGLLYCD--LPEPRKPLEKAVANFFSGSCAPCA------D 182

Query: 633 SGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAG 692
               P   LC LC G     C      QYFG+ GA +C+ +G GDVAFV+H+   E  A 
Sbjct: 183 GTDFP--QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLAN 235

Query: 693 RRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMV 752
           +                     TR  + EY+ C+L +VP   ++ R+   + D    L+ 
Sbjct: 236 K--------ADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLN 287

Query: 753 YALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVA 786
            A + +G   S EF     +S P   DL+F D A
Sbjct: 288 QAQEHFGKDKSKEF---QLFSSPHGKDLLFKDSA 318



 Score =  138 bits (333), Expect = 1e-31
 Identities = 121/425 (28%), Positives = 183/425 (43%), Gaps = 50/425 (11%)

Query: 401 QRTDDTGRPIELPFQLFSSNETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAEKA 460
           Q  +  G+     FQLFSS    DLL +DS   F+ +     A        Y+G +   A
Sbjct: 288 QAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDA------KMYLGYEYVTA 341

Query: 461 VMGIRD--CP------VKRAALCVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
           +  +R+  CP       K    C  S  E  KC +      + +   ++ C  A ++  C
Sbjct: 342 IRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEW-----SVNSVGKIECVSAETTEDC 396

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDSW-------YYAVAVAKEQD 565
              I  G  D    D G  ++ A    LVP + E Y+  D+        Y+AVAV K+  
Sbjct: 397 IAKIMNGEADAMSLDGG-FVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA 455

Query: 566 PDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGA 625
            D     L+ K +CHT +G  AGW  P+  L +    +   C       E++++ CAPG+
Sbjct: 456 SDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYN----KINHCR----FDEFFSEGCAPGS 507

Query: 626 LSSEYVDSGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTA 685
                 DS      +LC LC G+    C  +  E Y+G+ GA RC+VE  GDVAFV+H  
Sbjct: 508 KK----DS------SLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVE-KGDVAFVKHQT 556

Query: 686 PAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELD 745
             + + G+  + WA+             GTR  + EY +C+L + P   ++ R +  E  
Sbjct: 557 VPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKD-KEAC 615

Query: 746 AFSNLMVYALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNTRSAEIIAGP 805
               L      F   VT    +F +F S+    DL+F D  V L  L H+  + E   G 
Sbjct: 616 VHKILRQQQHLFGSNVTDCSGNFCLFRSET--KDLLFRDDTVCLAKL-HDRNTYEKYLGE 672

Query: 806 ALLRA 810
             ++A
Sbjct: 673 EYVKA 677



 Score =  124 bits (298), Expect = 2e-27
 Identities = 88/284 (30%), Positives = 141/284 (49%), Gaps = 34/284 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC+         K +  +D   + C K     +C++ +   EA  + L
Sbjct: 25  VRWCAVSEHEATKCQSFRDHM---KSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTL 81

Query: 101 DAGEVYVAGRY-HSLVPILQELDGRGEPYQ---YSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           DAG VY A    ++L P++ E  G  E  Q   Y+VAVV+K        G+ +  +RG K
Sbjct: 82  DAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDS------GFQMNQLRGKK 135

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHV-KSATEYFGESCAPNSLKDLYNPIGD 215
           +C   +G  AGW +PI +L  +    + +    + K+   +F  SCAP +        G 
Sbjct: 136 SCHTGLGRSAGWNIPIGLLYCD----LPEPRKPLEKAVANFFSGSCAPCA-------DGT 184

Query: 216 NSDKLCKLCYGGAGIRCTLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILG 275
           +  +LC+LC    G  C+  + + GY GA KCL  + +GD+AFV+ +TI   L +     
Sbjct: 185 DFPQLCQLC---PGCGCSTLNQYFGYSGAFKCL-KDGAGDVAFVKHSTIFENLANKA--- 237

Query: 276 GITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPE 319
               DQ+EL+C D +R+PV E++ C+  +VP+  +V  S    E
Sbjct: 238 --DRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKE 279



 Score =  117 bits (281), Expect = 2e-25
 Identities = 87/284 (30%), Positives = 133/284 (46%), Gaps = 48/284 (16%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E+ KC++   +S+           +++C  A   E+C+  +   EA  + L
Sbjct: 361 VKWCALSHHERLKCDEWSVNSVG----------KIECVSAETTEDCIAKIMNGEADAMSL 410

Query: 101 DAGEVYVAGRYHSLVPILQE-------LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMR 153
           D G VY+AG+   LVP+L E        +   E   ++VAVV+K              ++
Sbjct: 411 DGGFVYIAGKC-GLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA-----SDLTWDNLK 464

Query: 154 GAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPI 213
           G K+C  +VG  AGW +P+ +L      K+  C        E+F E CAP S KD     
Sbjct: 465 GKKSCHTAVGRTAGWNIPMGLLYN----KINHCR-----FDEFFSEGCAPGSKKD----- 510

Query: 214 GDNSDKLCKLCYGGAGIRC--TLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSH 271
                 LCKLC G     C     + + GY GA +CLV    GD+AFV+  T+       
Sbjct: 511 ----SSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLV--EKGDVAFVKHQTVPQNTGGK 564

Query: 272 KI---LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
                   + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 565 NPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 608


>DQ923758-1|ABI97197.1|  698|Homo sapiens transferrin protein.
          Length = 698

 Score =  139 bits (337), Expect = 3e-32
 Identities = 108/334 (32%), Positives = 153/334 (45%), Gaps = 34/334 (10%)

Query: 460 AVMGI-RDCPVKRAALCVTSDPEMDKCVKMRRALKAA--SLSPELSCWRAHSSRHCARAI 516
           AV+G+    P K    C  S+ E  KC   R  +K+   S  P ++C +  S   C RAI
Sbjct: 12  AVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAI 71

Query: 517 AAGSCDFALFDAGDMLHA-AQHDRLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTY 572
           AA   D    DAG +  A    + L P + E Y S +   ++YYAVAV K+ D    +  
Sbjct: 72  AANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQ 130

Query: 573 LRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVD 632
           LR K +CHTG+G +AGW  P+  L  +  +         A A +++ SCAP A      D
Sbjct: 131 LRGKKSCHTGLGRSAGWNIPIGLLYCD--LPEPRKPLEKAVANFFSGSCAPCA------D 182

Query: 633 SGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAG 692
               P   LC LC G     C      QYFG+ GA +C+ +G GDVAFV+H+   E  A 
Sbjct: 183 GTDFP--QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLAN 235

Query: 693 RRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMV 752
           +                     TR  + EY+ C+L +VP   ++ R+   + D    L+ 
Sbjct: 236 K--------ADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSIGGKEDLIWELLN 287

Query: 753 YALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVA 786
            A + +G   S EF     +S P   DL+F D A
Sbjct: 288 QAQEHFGKDKSKEF---QLFSSPHGKDLLFKDSA 318



 Score =  138 bits (333), Expect = 1e-31
 Identities = 121/425 (28%), Positives = 183/425 (43%), Gaps = 50/425 (11%)

Query: 401 QRTDDTGRPIELPFQLFSSNETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAEKA 460
           Q  +  G+     FQLFSS    DLL +DS   F+ +     A        Y+G +   A
Sbjct: 288 QAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDA------KMYLGYEYVTA 341

Query: 461 VMGIRD--CP------VKRAALCVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
           +  +R+  CP       K    C  S  E  KC +      + +   ++ C  A ++  C
Sbjct: 342 IRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEW-----SVNSVGKIECVSAETTEDC 396

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDSW-------YYAVAVAKEQD 565
              I  G  D    D G  ++ A    LVP + E Y+  D+        Y+AVAV K+  
Sbjct: 397 IAKIMNGEADAMSLDGG-FVYIAGKCGLVPVLAENYNKSDNCEDTPGAGYFAVAVVKKSA 455

Query: 566 PDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGA 625
            D     L+ K +CHT +G  AGW  P+  L +    +   C       E++++ CAPG+
Sbjct: 456 SDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYN----KINHCR----FDEFFSEGCAPGS 507

Query: 626 LSSEYVDSGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTA 685
                 DS      +LC LC G+    C  +  E Y+G+ GA RC+VE  GDVAFV+H  
Sbjct: 508 KK----DS------SLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVE-KGDVAFVKHQT 556

Query: 686 PAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELD 745
             + + G+  + WA+             GTR  + EY +C+L + P   ++ R +  E  
Sbjct: 557 VPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKD-KEAC 615

Query: 746 AFSNLMVYALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNTRSAEIIAGP 805
               L      F   VT    +F +F S+    DL+F D  V L  L H+  + E   G 
Sbjct: 616 VHKILRQQQHLFGSNVTDCSGNFCLFRSET--KDLLFRDDTVCLAKL-HDRNTYEKYLGE 672

Query: 806 ALLRA 810
             ++A
Sbjct: 673 EYVKA 677



 Score =  124 bits (298), Expect = 2e-27
 Identities = 88/284 (30%), Positives = 141/284 (49%), Gaps = 34/284 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC+         K +  +D   + C K     +C++ +   EA  + L
Sbjct: 25  VRWCAVSEHEATKCQSFRDHM---KSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTL 81

Query: 101 DAGEVYVAGRY-HSLVPILQELDGRGEPYQ---YSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           DAG VY A    ++L P++ E  G  E  Q   Y+VAVV+K        G+ +  +RG K
Sbjct: 82  DAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDS------GFQMNQLRGKK 135

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHV-KSATEYFGESCAPNSLKDLYNPIGD 215
           +C   +G  AGW +PI +L  +    + +    + K+   +F  SCAP +        G 
Sbjct: 136 SCHTGLGRSAGWNIPIGLLYCD----LPEPRKPLEKAVANFFSGSCAPCA-------DGT 184

Query: 216 NSDKLCKLCYGGAGIRCTLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILG 275
           +  +LC+LC    G  C+  + + GY GA KCL  + +GD+AFV+ +TI   L +     
Sbjct: 185 DFPQLCQLC---PGCGCSTLNQYFGYSGAFKCL-KDGAGDVAFVKHSTIFENLANKA--- 237

Query: 276 GITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPE 319
               DQ+EL+C D +R+PV E++ C+  +VP+  +V  S    E
Sbjct: 238 --DRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSIGGKE 279



 Score =  116 bits (280), Expect = 3e-25
 Identities = 86/284 (30%), Positives = 134/284 (47%), Gaps = 48/284 (16%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E+ KC++   +S+           +++C  A   E+C+  +   EA  + L
Sbjct: 361 VKWCALSHHERLKCDEWSVNSVG----------KIECVSAETTEDCIAKIMNGEADAMSL 410

Query: 101 DAGEVYVAGRYHSLVPILQELDGRGEPYQ-------YSVAVVRKGGLPNIQPGYGLQAMR 153
           D G VY+AG+   LVP+L E   + +  +       ++VAVV+K              ++
Sbjct: 411 DGGFVYIAGKC-GLVPVLAENYNKSDNCEDTPGAGYFAVAVVKKSA-----SDLTWDNLK 464

Query: 154 GAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPI 213
           G K+C  +VG  AGW +P+ +L      K+  C        E+F E CAP S KD     
Sbjct: 465 GKKSCHTAVGRTAGWNIPMGLLYN----KINHCR-----FDEFFSEGCAPGSKKD----- 510

Query: 214 GDNSDKLCKLCYGGAGIRC--TLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSH 271
                 LCKLC G     C     + + GY GA +CLV    GD+AFV+  T+       
Sbjct: 511 ----SSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLV--EKGDVAFVKHQTVPQNTGGK 564

Query: 272 KI---LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
                   + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 565 NPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 608


>BC059367-1|AAH59367.1|  698|Homo sapiens transferrin protein.
          Length = 698

 Score =  139 bits (336), Expect = 4e-32
 Identities = 108/334 (32%), Positives = 152/334 (45%), Gaps = 34/334 (10%)

Query: 460 AVMGI-RDCPVKRAALCVTSDPEMDKCVKMRRALKAA--SLSPELSCWRAHSSRHCARAI 516
           AV+G+    P K    C  S+ E  KC   R  +K+   S  P ++C +  S   C RAI
Sbjct: 12  AVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAI 71

Query: 517 AAGSCDFALFDAGDMLHA-AQHDRLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTY 572
           AA   D    DAG +  A    + L P + E Y S +   ++YYAVAV K+ D    +  
Sbjct: 72  AANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQ 130

Query: 573 LRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVD 632
           LR K +CHTG+G +AGW  P+  L  +  +         A A +++ SCAP A      D
Sbjct: 131 LRGKKSCHTGLGRSAGWNIPIGLLYCD--LPEPRKPLEKAVANFFSGSCAPCA------D 182

Query: 633 SGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAG 692
               P   LC LC G     C      QYFG+ GA +C+  G GDVAFV+H+   E  A 
Sbjct: 183 GTDFP--QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKNGAGDVAFVKHSTIFENLAN 235

Query: 693 RRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMV 752
           +                     TR  + EY+ C+L +VP   ++ R+   + D    L+ 
Sbjct: 236 K--------ADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLN 287

Query: 753 YALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVA 786
            A + +G   S EF     +S P   DL+F D A
Sbjct: 288 QAQEHFGKDKSKEF---QLFSSPHGKDLLFKDSA 318



 Score =  138 bits (333), Expect = 1e-31
 Identities = 120/420 (28%), Positives = 180/420 (42%), Gaps = 40/420 (9%)

Query: 401 QRTDDTGRPIELPFQLFSSNETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAEKA 460
           Q  +  G+     FQLFSS    DLL +DS   F+ +      AK  L  +YV       
Sbjct: 288 QAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPP-RMDAKMYLGYEYVTAIRNLR 346

Query: 461 VMGIRDCPV---KRAALCVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIA 517
               ++ P    K    C  S  E  KC +      + +   ++ C  A ++  C   I 
Sbjct: 347 EGTCQEAPTDECKPVKWCALSHHERLKCDEW-----SVNSVGKIECVSAETTEDCIAKIM 401

Query: 518 AGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDSW-------YYAVAVAKEQDPDTDL 570
            G  D    D G  ++ A    LVP + E Y+  D+        Y+AVAV K+   D   
Sbjct: 402 NGEADAMSLDGG-FVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSASDLTW 460

Query: 571 TYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEY 630
             L+ K +CHT +G  AGW  P+  L +    +   C       E++++ CAPG+     
Sbjct: 461 DNLKGKKSCHTAVGRTAGWNIPMGLLYN----KINHCR----FDEFFSEGCAPGSKK--- 509

Query: 631 VDSGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVS 690
            DS      +LC LC G+    C  +  E Y+G+ GA RC+VE  GDVAFV+H    + +
Sbjct: 510 -DS------SLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVE-KGDVAFVKHQTVPQNT 561

Query: 691 AGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNL 750
            G+  + WA+             GTR  + EY +C+L + P   ++ R +  E      L
Sbjct: 562 GGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKD-KEACVHKIL 620

Query: 751 MVYALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNTRSAEIIAGPALLRA 810
                 F   VT    +F +F S+    DL+F D  V L  L H+  + E   G   ++A
Sbjct: 621 RQQQHLFGSNVTDCSGNFCLFRSET--KDLLFRDDTVCLAKL-HDRNTYEKYLGEEYVKA 677



 Score =  126 bits (303), Expect = 4e-28
 Identities = 89/284 (31%), Positives = 141/284 (49%), Gaps = 34/284 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC+         K +  +D   + C K     +C++ +   EA  + L
Sbjct: 25  VRWCAVSEHEATKCQSFRDHM---KSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTL 81

Query: 101 DAGEVYVAGRY-HSLVPILQELDGRGEPYQ---YSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           DAG VY A    ++L P++ E  G  E  Q   Y+VAVV+K        G+ +  +RG K
Sbjct: 82  DAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDS------GFQMNQLRGKK 135

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHV-KSATEYFGESCAPNSLKDLYNPIGD 215
           +C   +G  AGW +PI +L  +    + +    + K+   +F  SCAP +        G 
Sbjct: 136 SCHTGLGRSAGWNIPIGLLYCD----LPEPRKPLEKAVANFFSGSCAPCA-------DGT 184

Query: 216 NSDKLCKLCYGGAGIRCTLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILG 275
           +  +LC+LC    G  C+  + + GY GA KCL  N +GD+AFV+ +TI   L +     
Sbjct: 185 DFPQLCQLC---PGCGCSTLNQYFGYSGAFKCL-KNGAGDVAFVKHSTIFENLANKA--- 237

Query: 276 GITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPE 319
               DQ+EL+C D +R+PV E++ C+  +VP+  +V  S    E
Sbjct: 238 --DRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKE 279



 Score =  117 bits (281), Expect = 2e-25
 Identities = 87/284 (30%), Positives = 133/284 (46%), Gaps = 48/284 (16%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E+ KC++   +S+           +++C  A   E+C+  +   EA  + L
Sbjct: 361 VKWCALSHHERLKCDEWSVNSVG----------KIECVSAETTEDCIAKIMNGEADAMSL 410

Query: 101 DAGEVYVAGRYHSLVPILQE-------LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMR 153
           D G VY+AG+   LVP+L E        +   E   ++VAVV+K              ++
Sbjct: 411 DGGFVYIAGKC-GLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA-----SDLTWDNLK 464

Query: 154 GAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPI 213
           G K+C  +VG  AGW +P+ +L      K+  C        E+F E CAP S KD     
Sbjct: 465 GKKSCHTAVGRTAGWNIPMGLLYN----KINHCR-----FDEFFSEGCAPGSKKD----- 510

Query: 214 GDNSDKLCKLCYGGAGIRC--TLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSH 271
                 LCKLC G     C     + + GY GA +CLV    GD+AFV+  T+       
Sbjct: 511 ----SSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLV--EKGDVAFVKHQTVPQNTGGK 564

Query: 272 KI---LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
                   + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 565 NPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 608


>AK222755-1|BAD96475.1|  698|Homo sapiens transferrin variant
           protein.
          Length = 698

 Score =  139 bits (336), Expect = 4e-32
 Identities = 108/334 (32%), Positives = 153/334 (45%), Gaps = 34/334 (10%)

Query: 460 AVMGI-RDCPVKRAALCVTSDPEMDKCVKMRRALKAA--SLSPELSCWRAHSSRHCARAI 516
           AV+G+    P K    C  S+ E  KC   R  +K+   S  P ++C +  S   C RAI
Sbjct: 12  AVLGLCLAVPDKTVRWCAVSEHEATKCQSFRDHMKSVIPSDGPSVACVKKASYLDCIRAI 71

Query: 517 AAGSCDFALFDAGDMLHA-AQHDRLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTY 572
           AA   D    DAG +  A    + L P + E Y S +   ++YYAVAV K+ D    +  
Sbjct: 72  AANEADAVTLDAGLVYDAYLAPNNLKPEVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQ 130

Query: 573 LRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVD 632
           LR K +CHTG+G +AGW  P+  L  +  +         A A +++ SCAP A      D
Sbjct: 131 LRGKKSCHTGLGRSAGWNIPIGLLYCD--LPEPRKPLEKAVANFFSGSCAPCA------D 182

Query: 633 SGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAG 692
               P   LC LC G     C      QYFG+ GA +C+ +G GDVAFV+H+   E  A 
Sbjct: 183 GTDFP--QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLAN 235

Query: 693 RRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMV 752
           +                     TR  + EY+ C+L +VP   ++ R+   + D    L+ 
Sbjct: 236 K--------ADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLN 287

Query: 753 YALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVA 786
            A + +G   S EF     +S P   DL+F D A
Sbjct: 288 QAQEHFGKDKSKEF---QLFSSPHGKDLLFKDSA 318



 Score =  138 bits (333), Expect = 1e-31
 Identities = 121/425 (28%), Positives = 183/425 (43%), Gaps = 50/425 (11%)

Query: 401 QRTDDTGRPIELPFQLFSSNETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAEKA 460
           Q  +  G+     FQLFSS    DLL +DS   F+ +     A        Y+G +   A
Sbjct: 288 QAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMDA------KMYLGYEYVTA 341

Query: 461 VMGIRD--CP------VKRAALCVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
           +  +R+  CP       K    C  S  E  KC +      + +   ++ C  A ++  C
Sbjct: 342 IRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEW-----SVNSVGKIECVSAETTEDC 396

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDSW-------YYAVAVAKEQD 565
              I  G  D    D G  ++ A    LVP + E Y+  D+        Y+AVAV K+  
Sbjct: 397 IAKIMNGEADAMSLDGG-FVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA 455

Query: 566 PDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGA 625
            D     L+ K +CHT +G  AGW  P+  L +    +   C       E++++ CAPG+
Sbjct: 456 SDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYN----KINHCR----FDEFFSEGCAPGS 507

Query: 626 LSSEYVDSGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTA 685
                 DS      +LC LC G+    C  +  E Y+G+ GA RC+VE  GDVAFV+H  
Sbjct: 508 KK----DS------SLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVE-KGDVAFVKHQT 556

Query: 686 PAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELD 745
             + + G+  + WA+             GTR  + EY +C+L + P   ++ R +  E  
Sbjct: 557 VPQNTGGKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKD-KEAC 615

Query: 746 AFSNLMVYALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNTRSAEIIAGP 805
               L      F   VT    +F +F S+    DL+F D  V L  L H+  + E   G 
Sbjct: 616 VHKILRQQQHLFGSNVTDCSGNFCLFRSET--KDLLFRDDTVCLAKL-HDRNTYEKYLGE 672

Query: 806 ALLRA 810
             ++A
Sbjct: 673 EYVKA 677



 Score =  121 bits (292), Expect = 9e-27
 Identities = 88/284 (30%), Positives = 140/284 (49%), Gaps = 34/284 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC+         K +  +D   + C K     +C++ +   EA  + L
Sbjct: 25  VRWCAVSEHEATKCQSFRDHM---KSVIPSDGPSVACVKKASYLDCIRAIAANEADAVTL 81

Query: 101 DAGEVYVAGRY-HSLVPILQELDGRGEPYQ---YSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           DAG VY A    ++L P + E  G  E  Q   Y+VAVV+K        G+ +  +RG K
Sbjct: 82  DAGLVYDAYLAPNNLKPEVAEFYGSKEDPQTFYYAVAVVKKDS------GFQMNQLRGKK 135

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHV-KSATEYFGESCAPNSLKDLYNPIGD 215
           +C   +G  AGW +PI +L  +    + +    + K+   +F  SCAP +        G 
Sbjct: 136 SCHTGLGRSAGWNIPIGLLYCD----LPEPRKPLEKAVANFFSGSCAPCA-------DGT 184

Query: 216 NSDKLCKLCYGGAGIRCTLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILG 275
           +  +LC+LC    G  C+  + + GY GA KCL  + +GD+AFV+ +TI   L +     
Sbjct: 185 DFPQLCQLC---PGCGCSTLNQYFGYSGAFKCL-KDGAGDVAFVKHSTIFENLANKA--- 237

Query: 276 GITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPE 319
               DQ+EL+C D +R+PV E++ C+  +VP+  +V  S    E
Sbjct: 238 --DRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKE 279



 Score =  117 bits (281), Expect = 2e-25
 Identities = 87/284 (30%), Positives = 133/284 (46%), Gaps = 48/284 (16%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E+ KC++   +S+           +++C  A   E+C+  +   EA  + L
Sbjct: 361 VKWCALSHHERLKCDEWSVNSVG----------KIECVSAETTEDCIAKIMNGEADAMSL 410

Query: 101 DAGEVYVAGRYHSLVPILQE-------LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMR 153
           D G VY+AG+   LVP+L E        +   E   ++VAVV+K              ++
Sbjct: 411 DGGFVYIAGKC-GLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA-----SDLTWDNLK 464

Query: 154 GAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPI 213
           G K+C  +VG  AGW +P+ +L      K+  C        E+F E CAP S KD     
Sbjct: 465 GKKSCHTAVGRTAGWNIPMGLLYN----KINHCR-----FDEFFSEGCAPGSKKD----- 510

Query: 214 GDNSDKLCKLCYGGAGIRC--TLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSH 271
                 LCKLC G     C     + + GY GA +CLV    GD+AFV+  T+       
Sbjct: 511 ----SSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLV--EKGDVAFVKHQTVPQNTGGK 564

Query: 272 KI---LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
                   + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 565 NPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 608


>X52941-1|CAA37116.1|  709|Homo sapiens protein ( Human LTF mRNA for
           lactoferrin (lactotransferrin). ).
          Length = 709

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 27  CAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 85

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 86  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 144

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 145 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 195

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 196 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 246

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 247 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 304

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 305 QLFGSPSGQKDLLFKDSAIGFSRVP 329



 Score =  125 bits (302), Expect = 6e-28
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 290 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 343

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 344 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 398

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 399 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 457

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 458 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 509

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 510 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 559

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 560 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 619

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 620 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 674

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 675 TTYEKYLGP 683



 Score =  119 bits (286), Expect = 5e-26
 Identities = 85/304 (27%), Positives = 148/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 24  VQWCAVSQPEATKCFQWQRNMRKVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 77

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 78  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 131

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 132 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 184

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 185 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 240

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 241 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 294

Query: 334 LYGE 337
            +G+
Sbjct: 295 KFGK 298



 Score =   99 bits (238), Expect = 3e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 334 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 387

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 388 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 442

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 443 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 496

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 497 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 538

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 539 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 597

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 598 RKPVTEARSCHLAMAPNHAVVS 619


>U07643-1|AAB60324.1|  711|Homo sapiens lactoferrin protein.
          Length = 711

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  125 bits (302), Expect = 6e-28
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  119 bits (286), Expect = 5e-26
 Identities = 85/304 (27%), Positives = 148/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRKVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score =   99 bits (238), Expect = 3e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>M93150-1|AAA36159.1|  711|Homo sapiens lactoferrin protein.
          Length = 711

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CTVSQPEATKCFQWQRNMRRVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  125 bits (302), Expect = 6e-28
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  121 bits (291), Expect = 1e-26
 Identities = 86/304 (28%), Positives = 149/304 (49%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WCT+S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCTVSQPEATKCFQWQRNMRRVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score =   99 bits (238), Expect = 3e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>M83205-1|AAA58656.1|  706|Homo sapiens HLF2 protein.
          Length = 706

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 24  CAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 82

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 83  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 141

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 142 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 192

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 193 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 243

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 244 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 301

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 302 QLFGSPSGQKDLLFKDSAIGFSRVP 326



 Score =  125 bits (301), Expect = 8e-28
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 287 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 340

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 341 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 395

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 396 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLGENYKSQQSSDPDPNCVDRPVEGYLAVA 454

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 455 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 506

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 507 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 556

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 557 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 616

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 617 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 671

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 672 TTYEKYLGP 680



 Score =  119 bits (286), Expect = 5e-26
 Identities = 85/304 (27%), Positives = 148/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 21  VQWCAVSQPEATKCFQWQRNMRKVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 74

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 75  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 128

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 129 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 181

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 182 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 237

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 238 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 291

Query: 334 LYGE 337
            +G+
Sbjct: 292 KFGK 295



 Score = 99.5 bits (237), Expect = 4e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 331 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 384

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 385 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLGENYKSQQSSDPD 439

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 440 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 493

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 494 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 535

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 536 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 594

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 595 RKPVTEARSCHLAMAPNHAVVS 616


>M83202-1|AAA59511.1|  711|Homo sapiens lactoferrin protein.
          Length = 711

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  125 bits (301), Expect = 8e-28
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDEG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  119 bits (286), Expect = 5e-26
 Identities = 85/304 (27%), Positives = 148/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRKVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score = 99.5 bits (237), Expect = 4e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDEGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>M73700-1|AAA59479.1|  710|Homo sapiens neutrophil lactoferrin
           protein.
          Length = 710

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 28  CAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 86

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 87  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 145

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 146 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 196

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 197 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 247

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 248 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 305

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 306 QLFGSPSGQKDLLFKDSAIGFSRVP 330



 Score =  125 bits (302), Expect = 6e-28
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 291 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 344

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 345 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 399

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 400 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 458

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 459 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 510

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 511 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 560

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 561 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 620

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 621 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 675

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 676 TTYEKYLGP 684



 Score =  119 bits (286), Expect = 5e-26
 Identities = 85/304 (27%), Positives = 148/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 25  VQWCAVSQPEATKCFQWQRNMRKVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 78

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 79  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 132

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 133 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 185

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 186 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 241

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 242 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 295

Query: 334 LYGE 337
            +G+
Sbjct: 296 KFGK 299



 Score =   99 bits (238), Expect = 3e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 335 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 388

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 389 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 443

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 444 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 497

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 498 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 539

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 540 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 598

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 599 RKPVTEARSCHLAMAPNHAVVS 620


>DQ522304-1|ABF69105.1|  353|Homo sapiens lactoferrin protein.
          Length = 353

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRRVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  119 bits (286), Expect = 5e-26
 Identities = 85/304 (27%), Positives = 148/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRRVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300


>BC015823-1|AAH15823.1|  711|Homo sapiens lactotransferrin protein.
          Length = 711

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQCLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  124 bits (298), Expect = 2e-27
 Identities = 114/429 (26%), Positives = 180/429 (41%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y  VA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLTVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  115 bits (277), Expect = 6e-25
 Identities = 84/304 (27%), Positives = 147/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRKVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++  K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQCLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score =   99 bits (238), Expect = 3e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LTVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>BC015822-1|AAH15822.1|  711|Homo sapiens lactotransferrin protein.
          Length = 711

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  125 bits (301), Expect = 8e-28
 Identities = 114/429 (26%), Positives = 180/429 (41%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y  VA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLTVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCEPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  119 bits (286), Expect = 5e-26
 Identities = 85/304 (27%), Positives = 148/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRKVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score =   99 bits (238), Expect = 3e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LTVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRC--T 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCEPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>AY493417-1|AAS72878.1|  711|Homo sapiens growth-inhibiting protein
           12 protein.
          Length = 711

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  125 bits (301), Expect = 8e-28
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTACKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  119 bits (286), Expect = 5e-26
 Identities = 85/304 (27%), Positives = 148/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRKVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score = 96.3 bits (229), Expect = 4e-19
 Identities = 93/322 (28%), Positives = 139/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY A +   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTACKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>AY178998-1|AAN75578.2|  711|Homo sapiens lactoferrin protein.
          Length = 711

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CTVSQPEATKCFQWQRNMRRVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  124 bits (299), Expect = 1e-27
 Identities = 114/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   + WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNDAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  121 bits (291), Expect = 1e-26
 Identities = 86/304 (28%), Positives = 149/304 (49%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WCT+S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCTVSQPEATKCFQWQRNMRRVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score = 99.5 bits (237), Expect = 4e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNDAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>AY165046-1|AAN63998.1|  711|Homo sapiens lactotransferrin precursor
           protein.
          Length = 711

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CTVSQPEATKCFQWQRNMRRVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  124 bits (299), Expect = 1e-27
 Identities = 114/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   + WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNDAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  121 bits (291), Expect = 1e-26
 Identities = 86/304 (28%), Positives = 149/304 (49%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WCT+S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCTVSQPEATKCFQWQRNMRRVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score = 99.5 bits (237), Expect = 4e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNDAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>AY137470-1|AAN11304.1|  711|Homo sapiens lactoferrin protein.
          Length = 711

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CTVSQPEATKCFQWQRNMRRVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  125 bits (302), Expect = 6e-28
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  121 bits (291), Expect = 1e-26
 Identities = 86/304 (28%), Positives = 149/304 (49%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WCT+S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCTVSQPEATKCFQWQRNMRRVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score =   99 bits (238), Expect = 3e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>AF332168-1|AAG48753.1|  711|Homo sapiens lactoferrin precursor
           protein.
          Length = 711

 Score =  138 bits (333), Expect = 1e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CTVSQPEATKCFQWQRNMRRVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  124 bits (299), Expect = 1e-27
 Identities = 114/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   + WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNDAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  121 bits (291), Expect = 1e-26
 Identities = 86/304 (28%), Positives = 149/304 (49%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WCT+S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCTVSQPEATKCFQWQRNMRRVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score = 99.5 bits (237), Expect = 4e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNDAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>AY875691-1|AAW71443.1|  711|Homo sapiens lactoferrin protein.
          Length = 711

 Score =  137 bits (331), Expect = 2e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRRVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRNAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  124 bits (300), Expect = 1e-27
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAEDAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKGVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  118 bits (284), Expect = 9e-26
 Identities = 85/304 (27%), Positives = 148/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRRVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRNAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score = 95.1 bits (226), Expect = 9e-19
 Identities = 92/322 (28%), Positives = 139/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A ++GD+AFV+  T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AEDAGDVAFVKGVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>AY360320-1|AAR12276.1|  709|Homo sapiens lactoferrin protein.
          Length = 709

 Score =  137 bits (331), Expect = 2e-31
 Identities = 101/325 (31%), Positives = 150/325 (46%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRRVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGSSRVP 331



 Score =  119 bits (286), Expect = 5e-26
 Identities = 85/304 (27%), Positives = 148/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRRVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score =  117 bits (282), Expect = 2e-25
 Identities = 114/429 (26%), Positives = 180/429 (41%), Gaps = 60/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I       S +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIG------SSRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
                 G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IAL--KGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 457

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 458 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 509

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 510 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 559

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   + WA+             G R  + E R C+L   P   ++ 
Sbjct: 560 VAFVKDVTVLQNTDGNNNDAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 619

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 620 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 674

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 675 TTYEKYLGP 683



 Score = 95.1 bits (226), Expect = 9e-19
 Identities = 94/322 (29%), Positives = 139/322 (43%), Gaps = 64/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+    + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIAL--KGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 442

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 443 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 496

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 497 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 538

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 539 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNDAWAKDLKLADFALLCLDGK 597

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 598 RKPVTEARSCHLAMAPNHAVVS 619


>X53961-1|CAA37914.1|  711|Homo sapiens precursor (AA -19 to 692)
           protein.
          Length = 711

 Score =  136 bits (330), Expect = 2e-31
 Identities = 101/325 (31%), Positives = 149/325 (45%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P   L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPTGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  125 bits (301), Expect = 8e-28
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTACKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  117 bits (281), Expect = 2e-25
 Identities = 84/304 (27%), Positives = 147/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRKVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +P   L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPTGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score = 96.3 bits (229), Expect = 4e-19
 Identities = 93/322 (28%), Positives = 139/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY A +   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTACKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>BC022347-1|AAH22347.1|  711|Homo sapiens lactotransferrin protein.
          Length = 711

 Score =  136 bits (328), Expect = 4e-31
 Identities = 101/325 (31%), Positives = 149/325 (45%), Gaps = 28/325 (8%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRKVC-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG    AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGRRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-TAPAEVSAGRRREFWARXXXXXXXX 708
             +C   + E YF + GA +C+ +G GDVAF+R  T   ++S    R+ +          
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRESTVFEDLSDEAERDEY---------E 248

Query: 709 XXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSF 768
                 TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F
Sbjct: 249 LLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--F 306

Query: 769 SMFYSQPPYSDLIFSDVAVRLKPLP 793
            +F S     DL+F D A+    +P
Sbjct: 307 QLFGSPSGQKDLLFKDSAIGFSRVP 331



 Score =  125 bits (302), Expect = 6e-28
 Identities = 115/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 292 RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 345

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 346 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 400

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 401 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 459

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 460 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 511

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 512 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 561

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   E WA+             G R  + E R C+L   P   ++ 
Sbjct: 562 VAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 621

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 622 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 676

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 677 TTYEKYLGP 685



 Score =  115 bits (277), Expect = 6e-25
 Identities = 85/304 (27%), Positives = 146/304 (48%), Gaps = 36/304 (11%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  +  G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRKVCGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSAT-EYFGESCAPNSLKDLYNPIGD 215
           +C       AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGRRRTAGWNVPIGTLRPF--LNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKI 273
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+   L     
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTVFEDLSDEA- 242

Query: 274 LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQ 333
                 D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  +
Sbjct: 243 ----ERDEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQE 296

Query: 334 LYGE 337
            +G+
Sbjct: 297 KFGK 300



 Score =   99 bits (238), Expect = 3e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 336 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 389

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 390 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 444

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 445 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 498

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 499 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 540

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 541 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGK 599

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 600 RKPVTEARSCHLAMAPNHAVVS 621


>U95626-5|AAB57795.1|  475|Homo sapiens lactoferrin protein.
          Length = 475

 Score =  124 bits (299), Expect = 1e-27
 Identities = 114/429 (26%), Positives = 181/429 (42%), Gaps = 58/429 (13%)

Query: 400 QQRTDDTGRPIELPFQLFSS-NETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAE 458
           +Q  +  G+     FQLF S +   DLL +DS I F       +    I +  Y+G    
Sbjct: 56  RQAQEKFGKDKSPKFQLFGSPSGQKDLLFKDSAIGF------SRVPPRIDSGLYLGSGYF 109

Query: 459 KAVMGIR----DCPVKRAAL--CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
            A+  +R    +   +RA +  C   + E+ KC +    L   S++    C  A ++  C
Sbjct: 110 TAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQWS-GLSEGSVT----CSSASTTEDC 164

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDS-------------WYYAVA 559
              +  G  D    D G  ++ A    LVP + E Y S  S              Y AVA
Sbjct: 165 IALVLKGEADAMSLDGG-YVYTAGKCGLVPVLAENYKSQQSSDPDPNCVDRPVEGYLAVA 223

Query: 560 VAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTK 619
           V +  D       ++ K +CHT +   AGW  P+  L +          G+    EY+++
Sbjct: 224 VVRRSDTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFNQ--------TGSCKFDEYFSQ 275

Query: 620 SCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMVEGGGD 677
           SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ E  GD
Sbjct: 276 SCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLAENAGD 325

Query: 678 VAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMG 737
           VAFV+     + + G   + WA+             G R  + E R C+L   P   ++ 
Sbjct: 326 VAFVKDVTVLQNTDGNNNDAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 385

Query: 738 RANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNT 796
           R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  L H  
Sbjct: 386 RMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLARL-HGK 440

Query: 797 RSAEIIAGP 805
            + E   GP
Sbjct: 441 TTYEKYLGP 449



 Score = 99.5 bits (237), Expect = 4e-20
 Identities = 94/322 (29%), Positives = 140/322 (43%), Gaps = 62/322 (19%)

Query: 17  SANYFGSENVNKIGSIQRKEGQDL-----ITWCTISALEQKKCEKLMKSSLQDKGLFGND 71
           S  Y GS     I ++++ E +       + WC +   E +KC +   S L +  +    
Sbjct: 100 SGLYLGSGYFTAIQNLRKSEEEVAARRARVVWCAVGEQELRKCNQW--SGLSEGSV---- 153

Query: 72  YIELQCKKAFDIEECMKWLEQEEATLLGLDAGEVYVAGRYHSLVPILQE----------- 120
                C  A   E+C+  + + EA  + LD G VY AG+   LVP+L E           
Sbjct: 154 ----TCSSASTTEDCIALVLKGEADAMSLDGGYVYTAGKC-GLVPVLAENYKSQQSSDPD 208

Query: 121 ---LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQ 177
              +D   E Y  +VAVVR+             +++G K+C  +V   AGW +P+ +L  
Sbjct: 209 PNCVDRPVEGY-LAVAVVRRS-----DTSLTWNSVKGKKSCHTAVDRTAGWNIPMGLLFN 262

Query: 178 EGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKLCKLCYGG--AGIRCT-- 233
           + G    D         EYF +SCAP S         D    LC LC G      +C   
Sbjct: 263 QTGSCKFD---------EYFSQSCAPGS---------DPRSNLCALCIGDEQGENKCVPN 304

Query: 234 LADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALLSHKILGGITE---DQFELICRDGS 290
             + + GY GA +CL A N+GD+AFV+D T+      +       +     F L+C DG 
Sbjct: 305 SNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQNTDGNNNDAWAKDLKLADFALLCLDGK 363

Query: 291 RRPVTEWEHCNWGKVPADAIVT 312
           R+PVTE   C+    P  A+V+
Sbjct: 364 RKPVTEARSCHLAMAPNHAVVS 385



 Score = 42.3 bits (95), Expect = 0.007
 Identities = 23/79 (29%), Positives = 42/79 (53%), Gaps = 2/79 (2%)

Query: 715 TRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSFSMFYSQ 774
           TR  + +++ C+L +VP   ++ R+ + + DA  NL+  A + +G   S +  F +F S 
Sbjct: 19  TRKPVDKFKDCHLARVPSHAVVARSVNGKEDAIWNLLRQAQEKFGKDKSPK--FQLFGSP 76

Query: 775 PPYSDLIFSDVAVRLKPLP 793
               DL+F D A+    +P
Sbjct: 77  SGQKDLLFKDSAIGFSRVP 95



 Score = 41.1 bits (92), Expect = 0.016
 Identities = 18/58 (31%), Positives = 35/58 (60%), Gaps = 2/58 (3%)

Query: 280 DQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPEQKRRYQNFLQRIVQLYGE 337
           D++EL+C D +R+PV +++ C+  +VP+ A+V  S    E      N L++  + +G+
Sbjct: 9   DEYELLCPDNTRKPVDKFKDCHLARVPSHAVVARSVNGKED--AIWNLLRQAQEKFGK 64


>AF508798-1|AAO14686.1|  234|Homo sapiens lactoferrin protein.
          Length = 234

 Score =  115 bits (277), Expect = 6e-25
 Identities = 75/215 (34%), Positives = 102/215 (47%), Gaps = 16/215 (7%)

Query: 475 CVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHCARAIAAGSCDFALFDAGDMLHA 534
           C  S PE  KC + +R ++     P +SC +  S   C +AIA    D    D G +  A
Sbjct: 29  CAVSQPEATKCFQWQRNMRKVR-GPPVSCIKRDSPIQCIQAIAENRADAVTLDGGFIYEA 87

Query: 535 AQHD-RLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWL 590
                +L P   EVY +     + YYAVAV K+      L  L+   +CHTG+   AGW 
Sbjct: 88  GLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG-SFQLNELQGLKSCHTGLRRTAGWN 146

Query: 591 YPLAYLLSN-GWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGAS 649
            P+  L     W  P     A A A +++ SC PGA      D G  P  NLC LC G  
Sbjct: 147 VPIGTLRPFLNWTGPPEPIEA-AVARFFSASCVPGA------DKGQFP--NLCRLCAGTG 197

Query: 650 FRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHT 684
             +C   + E YF + GA +C+ +G GDVAF+R +
Sbjct: 198 ENKCAFSSQEPYFSYSGAFKCLRDGAGDVAFIRES 232



 Score = 91.9 bits (218), Expect = 9e-18
 Identities = 66/231 (28%), Positives = 112/231 (48%), Gaps = 29/231 (12%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E  KC +  ++  + +G        + C K     +C++ + +  A  + L
Sbjct: 26  VQWCAVSQPEATKCFQWQRNMRKVRGP------PVSCIKRDSPIQCIQAIAENRADAVTL 79

Query: 101 DAGEVYVAGRY-HSLVPILQELDG---RGEPYQYSVAVVRKGGLPNIQPGYGLQAMRGAK 156
           D G +Y AG   + L P+  E+ G   +   + Y+VAVV+KGG       + L  ++G K
Sbjct: 80  DGGFIYEAGLAPYKLRPVAAEVYGTERQPRTHYYAVAVVKKGG------SFQLNELQGLK 133

Query: 157 ACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSA-TEYFGESCAPNSLKDLYNPIGD 215
           +C   +   AGW +PI  L     L  T     +++A   +F  SC P + K  +     
Sbjct: 134 SCHTGLRRTAGWNVPIGTL--RPFLNWTGPPEPIEAAVARFFSASCVPGADKGQF----- 186

Query: 216 NSDKLCKLCYGGAGIRCTLA--DPFAGYEGALKCLVANNSGDIAFVRDTTI 264
               LC+LC G    +C  +  +P+  Y GA KCL  + +GD+AF+R++T+
Sbjct: 187 --PNLCRLCAGTGENKCAFSSQEPYFSYSGAFKCL-RDGAGDVAFIRESTV 234


>M12525-1|AAA61142.1|  277|Homo sapiens TF protein.
          Length = 277

 Score =  114 bits (274), Expect = 1e-24
 Identities = 85/278 (30%), Positives = 128/278 (46%), Gaps = 30/278 (10%)

Query: 540 LVPFMQEVYSSGDSW-------YYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYP 592
           LVP + E Y+  D+        Y+AVAV K+   D     L+ K +CHT +G  AGW  P
Sbjct: 2   LVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSASDLTWDNLKGKKSCHTAVGRTAGWNIP 61

Query: 593 LAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHGASFRR 652
           +  L +    +   C       E++++ CAPG+      DS      +LC LC G+    
Sbjct: 62  MGLLYN----KINHCR----FDEFFSEGCAPGSKK----DS------SLCKLCMGSGLNL 103

Query: 653 CRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXX 712
           C  +  E Y+G+ GA RC+VE  GDVAFV+H    + + G+  + WA+            
Sbjct: 104 CEPNNKEGYYGYTGAFRCLVE-KGDVAFVKHQTVPQNTGGKNPDPWAKNLNEKDYELLCL 162

Query: 713 XGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQFYGAVTSDEFSFSMFY 772
            GTR  + EY +C+L + P   ++ R +  E      L      F   VT    +F +F 
Sbjct: 163 DGTRKPVEEYANCHLARAPNHAVVTRKD-KEACVHKILRQQQHLFGSNVTDCSGNFCLFR 221

Query: 773 SQPPYSDLIFSDVAVRLKPLPHNTRSAEIIAGPALLRA 810
           S+    DL+F D  V L  L H+  + E   G   ++A
Sbjct: 222 SET--KDLLFRDDTVCLAKL-HDRNTYEKYLGEEYVKA 256



 Score = 89.0 bits (211), Expect = 6e-17
 Identities = 56/166 (33%), Positives = 81/166 (48%), Gaps = 25/166 (15%)

Query: 152 MRGAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYN 211
           ++G K+C  +VG  AGW +P+ +L      K+  C        E+F E CAP S KD   
Sbjct: 42  LKGKKSCHTAVGRTAGWNIPMGLLYN----KINHCR-----FDEFFSEGCAPGSKKD--- 89

Query: 212 PIGDNSDKLCKLCYGGAGIRC--TLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHALL 269
                   LCKLC G     C     + + GY GA +CLV    GD+AFV+  T+     
Sbjct: 90  ------SSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLV--EKGDVAFVKHQTVPQNTG 141

Query: 270 SHKI---LGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
                     + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 142 GKNPDPWAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 187


>M11372-1|AAA61141.1|  490|Homo sapiens TF protein.
          Length = 490

 Score =  112 bits (269), Expect = 6e-24
 Identities = 87/273 (31%), Positives = 124/273 (45%), Gaps = 31/273 (11%)

Query: 518 AGSCDFALFDAGDMLHA-AQHDRLVPFMQEVYSSGD---SWYYAVAVAKEQDPDTDLTYL 573
           A   D    DAG +  A    + L P + E Y S +   ++YYAVAV K+ D    +  L
Sbjct: 1   ANEADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKK-DSGFQMNQL 59

Query: 574 RAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSEYVDS 633
           R K +CHTG+G +AGW  P+  L  +  +         A A +++ SCAP A      D 
Sbjct: 60  RGKKSCHTGLGRSAGWNIPIGLLYCD--LPEPRKPLEKAVANFFSGSCAPCA------DG 111

Query: 634 GSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEVSAGR 693
              P   LC LC G     C      QYFG+ GA +C+ +G GDVAFV+H+   E  A +
Sbjct: 112 TDFP--QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFENLANK 164

Query: 694 RREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVY 753
                                TR  + EY+ C+L +VP   ++ R+   + D    L+  
Sbjct: 165 --------ADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWELLNQ 216

Query: 754 ALQFYGAVTSDEFSFSMFYSQPPYSDLIFSDVA 786
           A + +G   S EF     +S P   DL+F D A
Sbjct: 217 AQEHFGKDKSKEF---QLFSSPHGKDLLFKDSA 246



 Score =  107 bits (257), Expect = 2e-22
 Identities = 92/302 (30%), Positives = 134/302 (44%), Gaps = 47/302 (15%)

Query: 401 QRTDDTGRPIELPFQLFSSNETTDLLLQDSTINFIILSESEQAAKHILNNKYVGDQAEKA 460
           Q  +  G+     FQLFSS    DLL +DS   F+ +     A        Y+G +   A
Sbjct: 216 QAQEHFGKDKSKEFQLFSSPHGKDLLFKDSAHGFLKVPPRMNA------KMYLGYEYVTA 269

Query: 461 VMGIRD--CP------VKRAALCVTSDPEMDKCVKMRRALKAASLSPELSCWRAHSSRHC 512
           +  +R+  CP       K    C  S  E  KC +      + +   ++ C  A ++  C
Sbjct: 270 IRNLREGTCPEAPTDECKPVKWCALSHHERLKCDEW-----SVNSVGKIECVSAETTEDC 324

Query: 513 ARAIAAGSCDFALFDAGDMLHAAQHDRLVPFMQEVYSSGDSW-------YYAVAVAKEQD 565
              I  G  D    D G  ++ A    LVP + E Y+  D+        Y+AVAV K+  
Sbjct: 325 IAKIMNGEADAMSLDGG-FVYIAGKCGLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA 383

Query: 566 PDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGA 625
            D     L+ K +CHT +G  AGW  P+  L +    +   C       E++++ CAPG+
Sbjct: 384 SDLTWDNLKGKKSCHTAVGRTAGWNIPMGLLYN----KINHCR----FDEFFSEGCAPGS 435

Query: 626 LSSEYVDSGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRH-T 684
                 DS      +LC LC G+    C  +  E Y+G+ GA RC+VE  GDVAFV+H T
Sbjct: 436 KK----DS------SLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLVE-KGDVAFVKHQT 484

Query: 685 AP 686
            P
Sbjct: 485 VP 486



 Score =  105 bits (252), Expect = 7e-22
 Identities = 77/231 (33%), Positives = 120/231 (51%), Gaps = 31/231 (13%)

Query: 94  EATLLGLDAGEVYVAGRY-HSLVPILQELDGRGEPYQ---YSVAVVRKGGLPNIQPGYGL 149
           EA  + LDAG VY A    ++L P++ E  G  E  Q   Y+VAVV+K        G+ +
Sbjct: 3   EADAVTLDAGLVYDAYLAPNNLKPVVAEFYGSKEDPQTFYYAVAVVKKDS------GFQM 56

Query: 150 QAMRGAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHV-KSATEYFGESCAPNSLKD 208
             +RG K+C   +G  AGW +PI +L  +    + +    + K+   +F  SCAP +   
Sbjct: 57  NQLRGKKSCHTGLGRSAGWNIPIGLLYCD----LPEPRKPLEKAVANFFSGSCAPCA--- 109

Query: 209 LYNPIGDNSDKLCKLCYGGAGIRCTLADPFAGYEGALKCLVANNSGDIAFVRDTTIQHAL 268
                G +  +LC+LC    G  C+  + + GY GA KCL  + +GD+AFV+ +TI   L
Sbjct: 110 ----DGTDFPQLCQLC---PGCGCSTLNQYFGYSGAFKCL-KDGAGDVAFVKHSTIFENL 161

Query: 269 LSHKILGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPE 319
            +         DQ+EL+C D +R+PV E++ C+  +VP+  +V  S    E
Sbjct: 162 ANKA-----DRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKE 207



 Score = 91.5 bits (217), Expect = 1e-17
 Identities = 72/233 (30%), Positives = 108/233 (46%), Gaps = 45/233 (19%)

Query: 41  ITWCTISALEQKKCEKLMKSSLQDKGLFGNDYIELQCKKAFDIEECMKWLEQEEATLLGL 100
           + WC +S  E+ KC++   +S+           +++C  A   E+C+  +   EA  + L
Sbjct: 289 VKWCALSHHERLKCDEWSVNSVG----------KIECVSAETTEDCIAKIMNGEADAMSL 338

Query: 101 DAGEVYVAGRYHSLVPILQE-------LDGRGEPYQYSVAVVRKGGLPNIQPGYGLQAMR 153
           D G VY+AG+   LVP+L E        +   E   ++VAVV+K              ++
Sbjct: 339 DGGFVYIAGKC-GLVPVLAENYNKSDNCEDTPEAGYFAVAVVKKSA-----SDLTWDNLK 392

Query: 154 GAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLYNPI 213
           G K+C  +VG  AGW +P+ +L      K+  C        E+F E CAP S KD     
Sbjct: 393 GKKSCHTAVGRTAGWNIPMGLLYN----KINHCR-----FDEFFSEGCAPGSKKD----- 438

Query: 214 GDNSDKLCKLCYGGAGIRC--TLADPFAGYEGALKCLVANNSGDIAFVRDTTI 264
                 LCKLC G     C     + + GY GA +CLV    GD+AFV+  T+
Sbjct: 439 ----SSLCKLCMGSGLNLCEPNNKEGYYGYTGAFRCLV--EKGDVAFVKHQTV 485


>M18642-1|AAA86665.1|  276|Homo sapiens lactoferrin protein.
          Length = 276

 Score =  103 bits (248), Expect = 2e-21
 Identities = 72/254 (28%), Positives = 114/254 (44%), Gaps = 26/254 (10%)

Query: 555 YYAVAVAKEQDPDTDLTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAA 614
           Y AVAV +  D       ++ K +CHT +   A W  P+  L +          G+    
Sbjct: 20  YLAVAVVRRSDTSLTWNSVKGKKSCHTAVDRTAAWNIPMGLLFNQ--------TGSCKFD 71

Query: 615 EYWTKSCAPGALSSEYVDSGSLPYDNLCHLCHG--ASFRRCRRDASEQYFGHVGAVRCMV 672
           EY+++SCAPG          S P  NLC LC G      +C  +++E+Y+G+ GA RC+ 
Sbjct: 72  EYFSQSCAPG----------SDPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCLA 121

Query: 673 EGGGDVAFVRHTAPAEVSAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPG 732
           E  GDVAFV+     + + G   E WA+             G R  + E R C+L   P 
Sbjct: 122 ENAGDVAFVKDVTVLQNTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPN 181

Query: 733 SVLMGRANHTELDAFSNLMVYALQFYGAVTSD-EFSFSMFYSQPPYSDLIFSDVAVRLKP 791
             ++ R +  +++    ++++    +G   SD    F +F S+    +L+F+D    L  
Sbjct: 182 HAVVSRMD--KVERLKQVLLHQQAKFGRNGSDCPDKFCLFQSET--KNLLFNDNTECLAR 237

Query: 792 LPHNTRSAEIIAGP 805
           L H   + E   GP
Sbjct: 238 L-HGKTTYEKYLGP 250



 Score = 76.6 bits (180), Expect = 4e-13
 Identities = 54/169 (31%), Positives = 79/169 (46%), Gaps = 26/169 (15%)

Query: 151 AMRGAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHVKSATEYFGESCAPNSLKDLY 210
           +++G K+C  +V   A W +P+ +L  + G    D         EYF +SCAP S     
Sbjct: 37  SVKGKKSCHTAVDRTAAWNIPMGLLFNQTGSCKFD---------EYFSQSCAPGS----- 82

Query: 211 NPIGDNSDKLCKLCYGG--AGIRCT--LADPFAGYEGALKCLVANNSGDIAFVRDTTIQH 266
               D    LC LC G      +C     + + GY GA +CL A N+GD+AFV+D T+  
Sbjct: 83  ----DPRSNLCALCIGDEQGENKCVPNSNERYYGYTGAFRCL-AENAGDVAFVKDVTVLQ 137

Query: 267 ALLSHKILGGITE---DQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
               +       +     F L+C DG R+PVTE   C+    P  A+V+
Sbjct: 138 NTDGNNNEAWAKDLKLADFALLCLDGKRKPVTEARSCHLAMAPNHAVVS 186


>BC020671-1|AAH20671.1|  180|Homo sapiens Unknown (protein for
           IMAGE:4722434) protein.
          Length = 180

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 56/175 (32%), Positives = 92/175 (52%), Gaps = 21/175 (12%)

Query: 146 GYGLQAMRGAKACFPSVGSLAGWVMPIHVLMQEGGLKVTDCNNHV-KSATEYFGESCAPN 204
           G+ +  +RG K+C   +G  AGW +PI +L  +    + +    + K+   +F  SCAP 
Sbjct: 2   GFQMNQLRGKKSCHTGLGRSAGWNIPIGLLYCD----LPEPRKPLEKAVANFFSGSCAPC 57

Query: 205 SLKDLYNPIGDNSDKLCKLCYGGAGIRCTLADPFAGYEGALKCLVANNSGDIAFVRDTTI 264
           +        G +  +LC+LC    G  C+  + + GY GA KCL  + +GD+AFV+ +TI
Sbjct: 58  A-------DGTDFPQLCQLC---PGCGCSTLNQYFGYSGAFKCL-KDGAGDVAFVKHSTI 106

Query: 265 QHALLSHKILGGITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVTTSAATPE 319
              L +         DQ+EL+C D +R+PV E++ C+  +VP+  +V  S    E
Sbjct: 107 FENLANKA-----DRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKE 156



 Score = 82.6 bits (195), Expect = 5e-15
 Identities = 58/190 (30%), Positives = 86/190 (45%), Gaps = 23/190 (12%)

Query: 570 LTYLRAKNTCHTGIGMAAGWLYPLAYLLSNGWIRPYGCNGAHAAAEYWTKSCAPGALSSE 629
           +  LR K +CHTG+G +AGW  P+  L  +  +         A A +++ SCAP A    
Sbjct: 5   MNQLRGKKSCHTGLGRSAGWNIPIGLLYCD--LPEPRKPLEKAVANFFSGSCAPCA---- 58

Query: 630 YVDSGSLPYDNLCHLCHGASFRRCRRDASEQYFGHVGAVRCMVEGGGDVAFVRHTAPAEV 689
             D    P   LC LC G     C      QYFG+ GA +C+ +G GDVAFV+H+   E 
Sbjct: 59  --DGTDFP--QLCQLCPG-----CGCSTLNQYFGYSGAFKCLKDGAGDVAFVKHSTIFEN 109

Query: 690 SAGRRREFWARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSN 749
            A +                     TR  + EY+ C+L +VP   ++ R+   + D    
Sbjct: 110 LANK--------ADRDQYELLCLDNTRKPVDEYKDCHLAQVPSHTVVARSMGGKEDLIWE 161

Query: 750 LMVYALQFYG 759
           L+  A + +G
Sbjct: 162 LLNQAQEHFG 171


>M17614-1|AAA61148.1|  135|Homo sapiens transferrin protein.
          Length = 135

 Score = 41.9 bits (94), Expect = 0.009
 Identities = 15/36 (41%), Positives = 25/36 (69%)

Query: 277 ITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
           + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 10  LNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 45



 Score = 35.1 bits (77), Expect = 1.1
 Identities = 30/113 (26%), Positives = 46/113 (40%), Gaps = 4/113 (3%)

Query: 698 WARXXXXXXXXXXXXXGTRAKMHEYRHCNLGKVPGSVLMGRANHTELDAFSNLMVYALQF 757
           WA+             GTR  + EY +C+L + P   ++ R +  E      L      F
Sbjct: 6   WAKNLNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVTRKD-KEACVHKILRQQQHLF 64

Query: 758 YGAVTSDEFSFSMFYSQPPYSDLIFSDVAVRLKPLPHNTRSAEIIAGPALLRA 810
              VT    +F +F S+    DL+F D  V L  L H+  + E   G   ++A
Sbjct: 65  GSNVTDCSGNFCLFRSET--KDLLFRDDTVCLAKL-HDRNTYEKYLGEEYVKA 114


>AF058327-1|AAC63506.1|   61|Homo sapiens transferrin protein.
          Length = 61

 Score = 41.9 bits (94), Expect = 0.009
 Identities = 15/36 (41%), Positives = 25/36 (69%)

Query: 277 ITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
           + E  +EL+C DG+R+PV E+ +C+  + P  A+VT
Sbjct: 10  LNEKDYELLCLDGTRKPVEEYANCHLARAPNHAVVT 45


>U88581-1|AAB97880.1|   61|Homo sapiens transferrin protein.
          Length = 61

 Score = 38.7 bits (86), Expect = 0.086
 Identities = 14/36 (38%), Positives = 24/36 (66%)

Query: 277 ITEDQFELICRDGSRRPVTEWEHCNWGKVPADAIVT 312
           + E  +EL+C DG+R+ V E+ +C+  + P  A+VT
Sbjct: 10  LNEKDYELLCLDGTRKSVEEYANCHLARAPNHAVVT 45


>DQ202398-1|ABA43715.1|  465|Homo sapiens ADAM21-like protein
           protein.
          Length = 465

 Score = 33.5 bits (73), Expect = 3.2
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 14/95 (14%)

Query: 186 CNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKL--CKLCYGGAGIRCTLADPFAGYEG 243
           CNNH +   E FG+  A ++ ++ Y  I    ++   C +  G   ++C ++D F    G
Sbjct: 337 CNNHDQHCREIFGKD-AKSASQNCYKEINSQGNRFGHCGI-NGTTYLKCHISDVFC---G 391

Query: 244 ALKCLVANNSGDIAFVRDTTIQHALLSHKILGGIT 278
            ++C    N  DI  ++D    H  L H  + G+T
Sbjct: 392 RVQC---ENVRDIPLLQD----HFTLQHTHINGVT 419


>BC109025-1|AAI09026.1|  721|Homo sapiens ADAM21 protein protein.
          Length = 721

 Score = 33.5 bits (73), Expect = 3.2
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 14/95 (14%)

Query: 186 CNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKL--CKLCYGGAGIRCTLADPFAGYEG 243
           CNNH +   E FG+  A ++ ++ Y  I    ++   C +  G   ++C ++D F    G
Sbjct: 506 CNNHDQHCREIFGKD-AKSASQNCYKEINSQGNRFGHCGI-NGTTYLKCHISDVFC---G 560

Query: 244 ALKCLVANNSGDIAFVRDTTIQHALLSHKILGGIT 278
            ++C    N  DI  ++D    H  L H  + G+T
Sbjct: 561 RVQC---ENVRDIPLLQD----HFTLQHTHINGVT 588


>BC109024-1|AAI09025.1|  722|Homo sapiens ADAM metallopeptidase
           domain 21 protein.
          Length = 722

 Score = 33.5 bits (73), Expect = 3.2
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 14/95 (14%)

Query: 186 CNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKL--CKLCYGGAGIRCTLADPFAGYEG 243
           CNNH +   E FG+  A ++ ++ Y  I    ++   C +  G   ++C ++D F    G
Sbjct: 507 CNNHDQHCREIFGKD-AKSASQNCYKEINSQGNRFGHCGI-NGTTYLKCHISDVFC---G 561

Query: 244 ALKCLVANNSGDIAFVRDTTIQHALLSHKILGGIT 278
            ++C    N  DI  ++D    H  L H  + G+T
Sbjct: 562 RVQC---ENVRDIPLLQD----HFTLQHTHINGVT 589


>AF158644-1|AAD55255.1|  722|Homo sapiens
           metalloproteinase-disintegrin protein.
          Length = 722

 Score = 33.5 bits (73), Expect = 3.2
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 14/95 (14%)

Query: 186 CNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKL--CKLCYGGAGIRCTLADPFAGYEG 243
           CNNH +   E FG+  A ++ ++ Y  I    ++   C +  G   ++C ++D F    G
Sbjct: 507 CNNHDQHCREIFGKD-AKSASQNCYKEINSQGNRFGHCGI-NGTTYLKCHISDVFC---G 561

Query: 244 ALKCLVANNSGDIAFVRDTTIQHALLSHKILGGIT 278
            ++C    N  DI  ++D    H  L H  + G+T
Sbjct: 562 RVQC---ENVRDIPLLQD----HFTLQHTHINGVT 589


>AF029900-1|AAC52042.1|  542|Homo sapiens ADAM 21 protein.
          Length = 542

 Score = 33.5 bits (73), Expect = 3.2
 Identities = 26/95 (27%), Positives = 45/95 (47%), Gaps = 14/95 (14%)

Query: 186 CNNHVKSATEYFGESCAPNSLKDLYNPIGDNSDKL--CKLCYGGAGIRCTLADPFAGYEG 243
           CNNH +   E FG+  A ++ ++ Y  I    ++   C +  G   ++C ++D F    G
Sbjct: 327 CNNHDQHCREIFGKD-AKSASQNCYKEINSQGNRFGHCGI-NGTTYLKCHISDVFC---G 381

Query: 244 ALKCLVANNSGDIAFVRDTTIQHALLSHKILGGIT 278
            ++C    N  DI  ++D    H  L H  + G+T
Sbjct: 382 RVQC---ENVRDIPLLQD----HFTLQHTHINGVT 409


  Database: human
    Posted date:  Oct 5, 2007 11:13 AM
  Number of letters in database: 73,234,838
  Number of sequences in database:  224,733
  
Lambda     K      H
   0.320    0.135    0.418 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 128,747,164
Number of Sequences: 224733
Number of extensions: 5627918
Number of successful extensions: 10161
Number of sequences better than 10.0: 48
Number of HSP's better than 10.0 without gapping: 43
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 9397
Number of HSP's gapped (non-prelim): 205
length of query: 855
length of database: 73,234,838
effective HSP length: 96
effective length of query: 759
effective length of database: 51,660,470
effective search space: 39210296730
effective search space used: 39210296730
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 69 (31.9 bits)

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