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Last updated: 2022/11/18
BLASTP 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= BGIBMGA000813-TA|BGIBMGA000813-PA|IPR002198|Short-chain
dehydrogenase/reductase SDR, IPR002347|Glucose/ribitol dehydrogenase
         (317 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_UPI00015B5303 Cluster: PREDICTED: similar to AT09608p; ...   303   4e-81
UniRef50_Q4QQ95 Cluster: IP09970p; n=6; Endopterygota|Rep: IP099...   250   3e-65
UniRef50_Q16J02 Cluster: Short-chain dehydrogenase; n=2; Diptera...   237   2e-61
UniRef50_Q9W404 Cluster: CG3842-PA, isoform A; n=11; Coelomata|R...   215   2e-54
UniRef50_Q8NBN7 Cluster: Retinol dehydrogenase 13; n=19; Deutero...   215   2e-54
UniRef50_Q8TC12 Cluster: Retinol dehydrogenase 11; n=49; Coeloma...   212   1e-53
UniRef50_Q4T7M3 Cluster: Chromosome undetermined SCAF8083, whole...   210   3e-53
UniRef50_Q0P435 Cluster: Zgc:153441; n=7; Clupeocephala|Rep: Zgc...   204   3e-51
UniRef50_Q6NY49 Cluster: LOC407663 protein; n=23; Eumetazoa|Rep:...   200   5e-50
UniRef50_UPI0000584FC7 Cluster: PREDICTED: hypothetical protein;...   185   1e-45
UniRef50_Q4SN30 Cluster: Chromosome 6 SCAF14544, whole genome sh...   182   8e-45
UniRef50_A7SMN3 Cluster: Predicted protein; n=1; Nematostella ve...   177   3e-43
UniRef50_Q9HBH5 Cluster: Retinol dehydrogenase 14; n=23; Deutero...   177   4e-43
UniRef50_A7RNX1 Cluster: Predicted protein; n=1; Nematostella ve...   170   4e-41
UniRef50_Q6TUD3 Cluster: LRRGT00111; n=3; Euteleostomi|Rep: LRRG...   167   3e-40
UniRef50_UPI00005873A1 Cluster: PREDICTED: hypothetical protein;...   165   1e-39
UniRef50_Q5U3E7 Cluster: Zgc:103654; n=6; Clupeocephala|Rep: Zgc...   165   1e-39
UniRef50_UPI0000D5685B Cluster: PREDICTED: similar to CG31235-PA...   156   6e-37
UniRef50_A5UPA5 Cluster: Short-chain dehydrogenase/reductase SDR...   155   1e-36
UniRef50_UPI000155BF31 Cluster: PREDICTED: similar to double sub...   153   8e-36
UniRef50_Q9VE80 Cluster: CG7675-PB, isoform B; n=9; Endopterygot...   152   1e-35
UniRef50_Q66IF0 Cluster: Zgc:101565; n=2; Clupeocephala|Rep: Zgc...   151   2e-35
UniRef50_Q4TAJ0 Cluster: Chromosome undetermined SCAF7304, whole...   150   4e-35
UniRef50_UPI0000D569DF Cluster: PREDICTED: similar to CG30495-PA...   149   7e-35
UniRef50_Q9U1Y6 Cluster: Putative uncharacterized protein dhs-24...   147   3e-34
UniRef50_Q8N5I4 Cluster: Dehydrogenase/reductase SDR family memb...   147   4e-34
UniRef50_UPI0000D57162 Cluster: PREDICTED: similar to short-chai...   145   1e-33
UniRef50_Q6UX07 Cluster: Dehydrogenase/reductase SDR family memb...   145   1e-33
UniRef50_Q8EQH7 Cluster: Alcohol dehydrogenase; n=1; Oceanobacil...   145   2e-33
UniRef50_Q7D9T6 Cluster: Oxidoreductase, short-chain dehydrogena...   144   3e-33
UniRef50_Q3E046 Cluster: NAD-dependent epimerase/dehydratase:Sho...   144   3e-33
UniRef50_A7RNF1 Cluster: Predicted protein; n=1; Nematostella ve...   143   5e-33
UniRef50_A6W5Z4 Cluster: Short-chain dehydrogenase/reductase SDR...   142   1e-32
UniRef50_Q2S6L7 Cluster: Retinol dehydrogenase 11; n=1; Saliniba...   141   2e-32
UniRef50_A7SUS7 Cluster: Predicted protein; n=1; Nematostella ve...   141   2e-32
UniRef50_Q5V0G9 Cluster: Oxidoreductase short-chain dehydrogenas...   141   2e-32
UniRef50_A1UAG7 Cluster: Short-chain dehydrogenase/reductase SDR...   140   4e-32
UniRef50_A7DHU1 Cluster: Short-chain dehydrogenase/reductase SDR...   139   1e-31
UniRef50_Q66KN7 Cluster: MGC85576 protein; n=13; Euteleostomi|Re...   138   1e-31
UniRef50_UPI00006CAF29 Cluster: oxidoreductase, short chain dehy...   138   2e-31
UniRef50_A4BA05 Cluster: Short chain dehydrogenase; n=1; Reineke...   138   2e-31
UniRef50_A1ZGJ1 Cluster: Retinol dehydrogenase 14; n=1; Microsci...   137   3e-31
UniRef50_A3RPY6 Cluster: Short chain dehydrogenase; n=1; Ralston...   136   5e-31
UniRef50_Q7T348 Cluster: Zgc:64106; n=7; Euteleostomi|Rep: Zgc:6...   135   1e-30
UniRef50_Q0VMN8 Cluster: Dehydrogenase/reductase; n=1; Alcanivor...   135   1e-30
UniRef50_UPI000155588C Cluster: PREDICTED: hypothetical protein;...   135   2e-30
UniRef50_UPI00003C0F00 Cluster: PREDICTED: similar to retinol de...   135   2e-30
UniRef50_Q1VVS7 Cluster: Short chain dehydrogenase; n=1; Psychro...   135   2e-30
UniRef50_Q9NZC7 Cluster: WW domain-containing oxidoreductase; n=...   135   2e-30
UniRef50_A1TDV9 Cluster: Short-chain dehydrogenase/reductase SDR...   134   2e-30
UniRef50_UPI00006D02C7 Cluster: oxidoreductase, short chain dehy...   133   7e-30
UniRef50_Q5YRJ5 Cluster: Putative short chain dehydrogenase; n=1...   132   9e-30
UniRef50_Q8LCE7 Cluster: Putativepod-specific dehydrogenase SAC2...   132   9e-30
UniRef50_UPI00006CBD6F Cluster: oxidoreductase, short chain dehy...   131   2e-29
UniRef50_A7HAP1 Cluster: Short-chain dehydrogenase/reductase SDR...   131   3e-29
UniRef50_Q0VQS4 Cluster: Oxidoreductase; n=1; Alcanivorax borkum...   130   5e-29
UniRef50_Q7VAC7 Cluster: Light dependent protochlorophyllide oxi...   129   1e-28
UniRef50_A4RTH5 Cluster: Predicted protein; n=2; Ostreococcus|Re...   128   1e-28
UniRef50_A5GU52 Cluster: Putative uncharacterized protein SynRCC...   128   2e-28
UniRef50_Q0S708 Cluster: Possible protochlorophyllide reductase;...   126   7e-28
UniRef50_Q8XQU5 Cluster: Probable kog1208, dehydrogenases with d...   124   2e-27
UniRef50_A6QQ52 Cluster: MGC152281 protein; n=5; Theria|Rep: MGC...   124   4e-27
UniRef50_Q2IV76 Cluster: Short-chain dehydrogenase/reductase pre...   121   2e-26
UniRef50_Q9RR99 Cluster: Oxidoreductase, short-chain dehydrogena...   121   3e-26
UniRef50_Q6SHU1 Cluster: Oxidoreductase, short-chain dehydrogena...   121   3e-26
UniRef50_Q1GUJ0 Cluster: Short-chain dehydrogenase/reductase SDR...   121   3e-26
UniRef50_A7QX66 Cluster: Chromosome undetermined scaffold_213, w...   120   6e-26
UniRef50_Q4WFI5 Cluster: Short-chain dehydrogenase/reductase, pu...   120   6e-26
UniRef50_A3KNN9 Cluster: MGC162294 protein; n=7; Euteleostomi|Re...   119   9e-26
UniRef50_Q9L2C8 Cluster: Putative oxidoreductase; n=1; Streptomy...   118   2e-25
UniRef50_UPI000066053A Cluster: dehydrogenase/reductase (SDR fam...   118   3e-25
UniRef50_Q0S8U0 Cluster: Probable oxidoreductase, short chain de...   118   3e-25
UniRef50_Q8SZ46 Cluster: RE17220p; n=3; Diptera|Rep: RE17220p - ...   118   3e-25
UniRef50_A0E897 Cluster: Chromosome undetermined scaffold_82, wh...   117   5e-25
UniRef50_A0PND0 Cluster: Oxidoreductase; n=4; Actinomycetales|Re...   116   8e-25
UniRef50_A2BY70 Cluster: Short-chain dehydrogenase/reductase (SD...   116   1e-24
UniRef50_Q2UG97 Cluster: Dehydrogenases with different specifici...   115   1e-24
UniRef50_A6RTJ2 Cluster: Putative uncharacterized protein; n=1; ...   115   2e-24
UniRef50_Q9XVS9 Cluster: Putative uncharacterized protein dhs-22...   114   2e-24
UniRef50_Q4S4S9 Cluster: Chromosome 2 SCAF14738, whole genome sh...   114   3e-24
UniRef50_A3WEU3 Cluster: Putative uncharacterized protein; n=1; ...   114   3e-24
UniRef50_Q2N830 Cluster: Oxidoreductase, short-chain dehydrogena...   113   4e-24
UniRef50_UPI0000D5714C Cluster: PREDICTED: similar to CG2070-PA;...   113   6e-24
UniRef50_A0JTU1 Cluster: Short-chain dehydrogenase/reductase SDR...   113   6e-24
UniRef50_UPI00015B6097 Cluster: PREDICTED: similar to CG11200-PA...   113   7e-24
UniRef50_O53537 Cluster: Possible oxidoreductase; n=9; cellular ...   113   7e-24
UniRef50_Q8YW93 Cluster: Alr1722 protein; n=6; Bacteria|Rep: Alr...   112   1e-23
UniRef50_Q399X9 Cluster: Short-chain dehydrogenase/reductase SDR...   112   1e-23
UniRef50_Q89V05 Cluster: Dehydrogenase; n=4; Proteobacteria|Rep:...   111   2e-23
UniRef50_A4XSH7 Cluster: Short-chain dehydrogenase/reductase SDR...   110   4e-23
UniRef50_Q7D3F2 Cluster: AGR_pAT_417p; n=5; Alphaproteobacteria|...   109   7e-23
UniRef50_A0YBR7 Cluster: Short chain dehydrogenase; n=1; marine ...   109   7e-23
UniRef50_UPI000058502F Cluster: PREDICTED: similar to CG2064-PA;...   109   9e-23
UniRef50_A5CQW0 Cluster: Putative short chain dehydrogenase/oxid...   108   2e-22
UniRef50_A0Z3B2 Cluster: Alcohol dehydrogenase; n=1; marine gamm...   108   2e-22
UniRef50_Q54BI7 Cluster: Putative uncharacterized protein; n=1; ...   108   2e-22
UniRef50_Q16QL9 Cluster: Short-chain dehydrogenase; n=5; Culicid...   108   2e-22
UniRef50_A6RXH3 Cluster: Putative uncharacterized protein; n=1; ...   108   2e-22
UniRef50_Q53877 Cluster: Ketoreductase; n=3; Streptomyces|Rep: K...   107   3e-22
UniRef50_Q9VLU5 Cluster: WW domain-containing oxidoreductase; n=...   107   3e-22
UniRef50_Q7K0F7 Cluster: GH19857p; n=4; Diptera|Rep: GH19857p - ...   107   4e-22
UniRef50_UPI000058766F Cluster: PREDICTED: similar to WW domain-...   107   5e-22
UniRef50_A4AEV0 Cluster: Short chain dehydrogenase; n=1; marine ...   107   5e-22
UniRef50_A0B1Z9 Cluster: Short-chain dehydrogenase/reductase SDR...   107   5e-22
UniRef50_Q4WLK4 Cluster: Oxidoreductase, short-chain dehydrogena...   106   6e-22
UniRef50_Q3WJ13 Cluster: Short-chain dehydrogenase/reductase SDR...   106   9e-22
UniRef50_Q39N41 Cluster: Short-chain dehydrogenase/reductase SDR...   105   2e-21
UniRef50_Q17GA5 Cluster: Short-chain dehydrogenase; n=1; Aedes a...   105   2e-21
UniRef50_A4CX59 Cluster: Short-chain dehydrogenase/reductase (SD...   103   5e-21
UniRef50_Q1QSD6 Cluster: Short-chain dehydrogenase/reductase SDR...   103   6e-21
UniRef50_UPI0000587008 Cluster: PREDICTED: hypothetical protein;...   103   8e-21
UniRef50_Q64PT9 Cluster: Putative oxidoreductase; n=7; Bacteroid...   103   8e-21
UniRef50_Q8RWK2 Cluster: Ribitol dehydrogenase-like; n=13; Magno...   102   1e-20
UniRef50_O74959 Cluster: Short chain dehydrogenase; n=1; Schizos...   102   1e-20
UniRef50_A4RS19 Cluster: Predicted protein; n=2; Ostreococcus|Re...   101   2e-20
UniRef50_Q0AP26 Cluster: Short-chain dehydrogenase/reductase SDR...   101   2e-20
UniRef50_A1G986 Cluster: Short-chain dehydrogenase/reductase SDR...   101   2e-20
UniRef50_Q9FQM0 Cluster: Forever young oxidoreductase; n=20; Mag...   101   2e-20
UniRef50_UPI0000E235EA Cluster: PREDICTED: similar to MGC81751 p...   101   3e-20
UniRef50_Q4UJ93 Cluster: Dehydrogenase/reductase (SDR family) X-...   101   3e-20
UniRef50_A0YA00 Cluster: Oxidoreductase, short-chain dehydrogena...   100   4e-20
UniRef50_A6G6M7 Cluster: Possible dehydrogenase; n=1; Plesiocyst...   100   6e-20
UniRef50_Q5CMZ5 Cluster: ENSANGP00000010899; n=2; Cryptosporidiu...   100   6e-20
UniRef50_UPI000058941E Cluster: PREDICTED: hypothetical protein;...    99   7e-20
UniRef50_Q5FS41 Cluster: Putative oxidoreductase; n=1; Gluconoba...    99   7e-20
UniRef50_UPI0000E475C8 Cluster: PREDICTED: similar to Retinol de...    99   1e-19
UniRef50_UPI0000DB7DE5 Cluster: PREDICTED: similar to retinol de...    99   1e-19
UniRef50_Q9RTQ6 Cluster: Daunorubicin C-13 ketoreductase; n=2; D...    99   1e-19
UniRef50_A0PJE2 Cluster: DHRS12 protein; n=23; Eumetazoa|Rep: DH...    99   1e-19
UniRef50_A3CUN1 Cluster: Short-chain dehydrogenase/reductase SDR...    99   2e-19
UniRef50_UPI0000D9F6C2 Cluster: PREDICTED: similar to dehydrogen...    98   2e-19
UniRef50_Q0S547 Cluster: Dehydrogenase; n=1; Rhodococcus sp. RHA...    98   3e-19
UniRef50_A6WFS0 Cluster: Short-chain dehydrogenase/reductase SDR...    97   7e-19
UniRef50_Q026V1 Cluster: Transcriptional regulator, Fis family; ...    96   9e-19
UniRef50_UPI0000D573DB Cluster: PREDICTED: similar to CG7675-PB,...    95   2e-18
UniRef50_A6LYK8 Cluster: Short-chain dehydrogenase/reductase SDR...    94   5e-18
UniRef50_Q54I93 Cluster: Putative uncharacterized protein; n=1; ...    94   5e-18
UniRef50_A0DVI8 Cluster: Chromosome undetermined scaffold_66, wh...    94   5e-18
UniRef50_A3Q3R2 Cluster: Short-chain dehydrogenase/reductase SDR...    93   6e-18
UniRef50_A3VT62 Cluster: Dehydrogenase; n=1; Parvularcula bermud...    93   9e-18
UniRef50_UPI00006CC409 Cluster: oxidoreductase, short chain dehy...    92   1e-17
UniRef50_A1G3M7 Cluster: Short-chain dehydrogenase/reductase SDR...    91   3e-17
UniRef50_A6QU72 Cluster: Predicted protein; n=2; Onygenales|Rep:...    91   3e-17
UniRef50_A7D2G2 Cluster: Short-chain dehydrogenase/reductase SDR...    91   3e-17
UniRef50_Q03326 Cluster: Probable oxidoreductase; n=12; Bacteria...    91   3e-17
UniRef50_UPI0000DB6DB5 Cluster: PREDICTED: similar to CG11200-PB...    91   3e-17
UniRef50_UPI000049A4BD Cluster: short chain dehydrogenase family...    91   3e-17
UniRef50_Q5DAF6 Cluster: SJCHGC01149 protein; n=1; Schistosoma j...    91   5e-17
UniRef50_Q19062 Cluster: Dehydrogenases, short chain protein 7; ...    91   5e-17
UniRef50_A5K293 Cluster: Oxidoreductase, short-chain dehydrogena...    91   5e-17
UniRef50_Q4UJ91 Cluster: Dehydrogenase/reductase (SDR family) X-...    91   5e-17
UniRef50_A6STP3 Cluster: Putative uncharacterized protein; n=1; ...    91   5e-17
UniRef50_Q54KS0 Cluster: Putative uncharacterized protein; n=3; ...    90   6e-17
UniRef50_Q0CJ32 Cluster: Putative uncharacterized protein; n=3; ...    90   6e-17
UniRef50_Q97DJ3 Cluster: Short-chain alcohol dehydrogenase famil...    89   1e-16
UniRef50_A0BGD0 Cluster: Chromosome undetermined scaffold_106, w...    89   1e-16
UniRef50_A2R494 Cluster: Contig An14c0200, complete genome; n=1;...    89   1e-16
UniRef50_Q26ER7 Cluster: Dehydrogenase/reductase; n=13; Bacteria...    89   1e-16
UniRef50_A4RWK8 Cluster: Predicted protein; n=1; Ostreococcus lu...    89   1e-16
UniRef50_A1CLH8 Cluster: Short-chain dehydrogenase; n=2; Fungi/M...    89   1e-16
UniRef50_A1SQ46 Cluster: Short-chain dehydrogenase/reductase SDR...    89   2e-16
UniRef50_Q7NKQ4 Cluster: Glr1423 protein; n=9; Bacteria|Rep: Glr...    88   2e-16
UniRef50_A3VMM7 Cluster: Dehydrogenase; n=1; Rhodobacterales bac...    88   2e-16
UniRef50_Q9LFS7 Cluster: Putative uncharacterized protein F1N13_...    88   2e-16
UniRef50_Q5V6R4 Cluster: Oxidoreductase; n=3; cellular organisms...    88   2e-16
UniRef50_Q3W5P1 Cluster: Short-chain dehydrogenase/reductase SDR...    88   3e-16
UniRef50_A6WAZ3 Cluster: Short-chain dehydrogenase/reductase SDR...    88   3e-16
UniRef50_Q0UI12 Cluster: Putative uncharacterized protein; n=1; ...    88   3e-16
UniRef50_Q98K50 Cluster: Mlr1637 protein; n=2; Proteobacteria|Re...    87   4e-16
UniRef50_A2R1L8 Cluster: Contig An13c0060, complete genome; n=2;...    87   4e-16
UniRef50_UPI0000D55E90 Cluster: PREDICTED: similar to CG11200-PB...    87   6e-16
UniRef50_A0D206 Cluster: Chromosome undetermined scaffold_35, wh...    87   6e-16
UniRef50_UPI000023E6D6 Cluster: hypothetical protein FG03303.1; ...    87   7e-16
UniRef50_Q9S1Q1 Cluster: Putative oxidoreductase; n=2; Streptomy...    87   7e-16
UniRef50_Q7X507 Cluster: Oxidoreductase; n=1; Streptomyces sp. C...    87   7e-16
UniRef50_Q0UKX1 Cluster: Predicted protein; n=1; Phaeosphaeria n...    87   7e-16
UniRef50_UPI0000E49E46 Cluster: PREDICTED: similar to Retinol de...    86   1e-15
UniRef50_A5ESF8 Cluster: Short-chain dehydrogenase/reductase SDR...    86   1e-15
UniRef50_A4A816 Cluster: Short-chain dehydrogenase/reductase SDR...    86   1e-15
UniRef50_A1T3N3 Cluster: Short-chain dehydrogenase/reductase SDR...    86   1e-15
UniRef50_A1DKR0 Cluster: Short-chain dehydrogenase; n=3; Trichoc...    86   1e-15
UniRef50_Q41HA4 Cluster: Short-chain dehydrogenase/reductase SDR...    85   2e-15
UniRef50_Q3VXB7 Cluster: Short-chain dehydrogenase/reductase SDR...    85   2e-15
UniRef50_A7HKH5 Cluster: Short-chain dehydrogenase/reductase SDR...    85   2e-15
UniRef50_A6N014 Cluster: Retinol dehydrogenase 11; n=8; Magnolio...    85   2e-15
UniRef50_A2ZC46 Cluster: Putative uncharacterized protein; n=1; ...    85   2e-15
UniRef50_UPI000023F261 Cluster: hypothetical protein FG04592.1; ...    85   2e-15
UniRef50_Q2TWW2 Cluster: Dehydrogenases with different specifici...    85   2e-15
UniRef50_A6SHG0 Cluster: Putative uncharacterized protein; n=1; ...    85   2e-15
UniRef50_Q82PZ7 Cluster: Putative dehydrogenase; n=2; Streptomyc...    83   9e-15
UniRef50_Q3WC47 Cluster: Short-chain dehydrogenase/reductase SDR...    83   9e-15
UniRef50_A5B364 Cluster: Putative uncharacterized protein; n=1; ...    83   9e-15
UniRef50_A3LNL9 Cluster: Predicted protein; n=6; Saccharomycetal...    83   9e-15
UniRef50_UPI000049935F Cluster: conserved hypothetical protein; ...    83   1e-14
UniRef50_Q17CG7 Cluster: Short-chain dehydrogenase; n=2; Culicid...    83   1e-14
UniRef50_Q5D9J1 Cluster: SJCHGC09542 protein; n=1; Schistosoma j...    82   2e-14
UniRef50_A4VT50 Cluster: Dehydrogenase with different specificit...    82   2e-14
UniRef50_A3LNP9 Cluster: Short-chain alcohol dehydrogenase; n=1;...    82   2e-14
UniRef50_A2R9B8 Cluster: Contig An17c0030, complete genome; n=6;...    82   2e-14
UniRef50_Q3WGZ8 Cluster: Short-chain dehydrogenase/reductase SDR...    81   3e-14
UniRef50_A5FBJ6 Cluster: Short-chain dehydrogenase/reductase SDR...    81   3e-14
UniRef50_UPI0000D57168 Cluster: PREDICTED: similar to CG7675-PB,...    81   4e-14
UniRef50_Q9PA04 Cluster: Ketoreductase; n=7; cellular organisms|...    81   4e-14
UniRef50_Q2UF38 Cluster: Dehydrogenases with different specifici...    80   6e-14
UniRef50_A4RXM2 Cluster: Predicted protein; n=2; Ostreococcus|Re...    80   8e-14
UniRef50_A1DKB8 Cluster: Short-chain oxidoreductase, putative; n...    80   8e-14
UniRef50_UPI000023EBC0 Cluster: hypothetical protein FG00213.1; ...    79   1e-13
UniRef50_Q9KG00 Cluster: BH0316 protein; n=1; Bacillus haloduran...    79   1e-13
UniRef50_A5CQ21 Cluster: Putative short chain alcohol dehydrogen...    79   1e-13
UniRef50_A4RXP8 Cluster: Predicted protein; n=2; Ostreococcus|Re...    79   1e-13
UniRef50_A0EEX1 Cluster: Chromosome undetermined scaffold_92, wh...    79   1e-13
UniRef50_A2QR41 Cluster: Contig An08c0130, complete genome; n=1;...    79   1e-13
UniRef50_Q4PDD2 Cluster: Putative uncharacterized protein; n=1; ...    79   1e-13
UniRef50_A2R0W5 Cluster: Remark: also show homology to different...    79   1e-13
UniRef50_Q4JMZ6 Cluster: Putative uncharacterized protein; n=1; ...    79   2e-13
UniRef50_A7QG31 Cluster: Chromosome undetermined scaffold_91, wh...    79   2e-13
UniRef50_Q4PD53 Cluster: Putative uncharacterized protein; n=1; ...    79   2e-13
UniRef50_Q61C15 Cluster: Putative uncharacterized protein CBG131...    78   3e-13
UniRef50_Q4W9Y6 Cluster: Oxidoreductase, short-chain dehydrogena...    78   3e-13
UniRef50_A0AC89 Cluster: Putative oxidoreductase; n=1; Streptomy...    78   3e-13
UniRef50_Q4QHL1 Cluster: Dehydrogenase-like protein; n=3; Leishm...    78   3e-13
UniRef50_A0D7N4 Cluster: Chromosome undetermined scaffold_40, wh...    78   3e-13
UniRef50_Q0C051 Cluster: Oxidoreductase, short chain dehydrogena...    77   5e-13
UniRef50_Q0UF48 Cluster: Putative uncharacterized protein; n=1; ...    77   5e-13
UniRef50_Q3WBA5 Cluster: Short-chain dehydrogenase/reductase SDR...    77   6e-13
UniRef50_A4T8M7 Cluster: Short-chain dehydrogenase/reductase SDR...    77   6e-13
UniRef50_Q7QES1 Cluster: ENSANGP00000019888; n=1; Anopheles gamb...    77   6e-13
UniRef50_UPI0000D57166 Cluster: PREDICTED: similar to CG2065-PA;...    77   8e-13
UniRef50_Q7XCH4 Cluster: NAD dependent epimerase/dehydratase fam...    77   8e-13
UniRef50_A1C4C7 Cluster: Short-chain dehydrogenase; n=7; Pezizom...    77   8e-13
UniRef50_Q9CDH0 Cluster: Oxidoreductase; n=3; Lactococcus lactis...    76   1e-12
UniRef50_Q6NLR7 Cluster: At5g04070; n=4; Magnoliophyta|Rep: At5g...    76   1e-12
UniRef50_A4R4N5 Cluster: Putative uncharacterized protein; n=1; ...    76   1e-12
UniRef50_Q2UB72 Cluster: Predicted protein; n=1; Aspergillus ory...    76   1e-12
UniRef50_Q5DEA2 Cluster: SJCHGC03296 protein; n=1; Schistosoma j...    75   2e-12
UniRef50_UPI0000498BBC Cluster: conserved hypothetical protein; ...    75   3e-12
UniRef50_Q5B8A4 Cluster: Putative uncharacterized protein; n=1; ...    75   3e-12
UniRef50_Q0C8N8 Cluster: Predicted protein; n=2; Trichocomaceae|...    75   3e-12
UniRef50_Q7SEJ0 Cluster: Putative uncharacterized protein NCU097...    74   4e-12
UniRef50_Q4WAX4 Cluster: Short-chain dehydrogenase, putative; n=...    74   4e-12
UniRef50_Q4S7K6 Cluster: Chromosome 13 SCAF14715, whole genome s...    74   6e-12
UniRef50_A0Y9Z7 Cluster: Oxidoreductase; n=1; marine gamma prote...    74   6e-12
UniRef50_A6QSP2 Cluster: Predicted protein; n=1; Ajellomyces cap...    74   6e-12
UniRef50_Q54NY5 Cluster: Putative uncharacterized protein; n=1; ...    73   7e-12
UniRef50_Q6C9P4 Cluster: Yarrowia lipolytica chromosome D of str...    73   7e-12
UniRef50_A3CQN6 Cluster: Dehydrogenase, eukaryotic-like, putativ...    73   1e-11
UniRef50_A2R6G5 Cluster: Contig An15c0250, complete genome; n=1;...    73   1e-11
UniRef50_A1ZQT0 Cluster: Dehydrogenase/ reductase 1; n=1; Micros...    72   2e-11
UniRef50_A0VWL5 Cluster: Oxidoreductase, short chain dehydrogena...    72   2e-11
UniRef50_Q6CA42 Cluster: Yarrowia lipolytica chromosome D of str...    72   2e-11
UniRef50_Q0UDK9 Cluster: Putative uncharacterized protein; n=1; ...    72   2e-11
UniRef50_Q26DQ7 Cluster: Short-chain dehydrogenases/reductases f...    71   3e-11
UniRef50_Q2HEV9 Cluster: Putative uncharacterized protein; n=1; ...    71   3e-11
UniRef50_A1CD02 Cluster: Putative uncharacterized protein; n=1; ...    71   3e-11
UniRef50_UPI000023D14C Cluster: hypothetical protein FG03819.1; ...    71   4e-11
UniRef50_Q89NN9 Cluster: Blr3799 protein; n=2; Bacteria|Rep: Blr...    71   4e-11
UniRef50_Q0U4A1 Cluster: Putative uncharacterized protein; n=1; ...    71   4e-11
UniRef50_A3M278 Cluster: Dehydrogenase/reductase; n=1; Acinetoba...    71   5e-11
UniRef50_A6RMZ9 Cluster: Putative uncharacterized protein; n=1; ...    71   5e-11
UniRef50_A6R7A6 Cluster: Putative uncharacterized protein; n=3; ...    71   5e-11
UniRef50_A5DD40 Cluster: Putative uncharacterized protein; n=2; ...    71   5e-11
UniRef50_A3LNQ0 Cluster: Short-chain alcohol dehydrogenase retin...    71   5e-11
UniRef50_Q9KZS7 Cluster: Putative oxidoreductase; n=1; Streptomy...    70   7e-11
UniRef50_Q8FU15 Cluster: Putative oxidoreductase; n=2; Corynebac...    70   7e-11
UniRef50_A0PPV6 Cluster: Dehydrogenase/reductase; n=1; Mycobacte...    70   7e-11
UniRef50_Q7S4I6 Cluster: Putative uncharacterized protein NCU081...    70   7e-11
UniRef50_Q8EMP9 Cluster: 3-oxoacyl-(Acyl carrier protein) reduct...    70   9e-11
UniRef50_A4CNY9 Cluster: Oxidoreductase, short chain dehydrogena...    70   9e-11
UniRef50_Q5AEE8 Cluster: Putative uncharacterized protein RSD1; ...    70   9e-11
UniRef50_Q42536 Cluster: Protochlorophyllide reductase A, chloro...    70   9e-11
UniRef50_UPI000023D82A Cluster: hypothetical protein FG07388.1; ...    69   1e-10
UniRef50_A3IS65 Cluster: Probable dehydrogenase/reductase; n=1; ...    69   1e-10
UniRef50_A7ESE6 Cluster: Putative uncharacterized protein; n=1; ...    69   1e-10
UniRef50_UPI0000E4A7BE Cluster: PREDICTED: similar to Retinol de...    69   2e-10
UniRef50_Q54IY2 Cluster: Putative uncharacterized protein; n=1; ...    69   2e-10
UniRef50_Q6CAB9 Cluster: Yarrowia lipolytica chromosome D of str...    69   2e-10
UniRef50_A1R3Z2 Cluster: Putative oxidoreductase, short chain de...    68   3e-10
UniRef50_P91013 Cluster: Dehydrogenases, short chain protein 1; ...    68   3e-10
UniRef50_A6R5Y9 Cluster: Predicted protein; n=1; Ajellomyces cap...    68   3e-10
UniRef50_A1ZLA5 Cluster: Retinol dehydrogenase 13; n=1; Microsci...    68   4e-10
UniRef50_Q109A3 Cluster: Oxidoreductase, short chain dehydrogena...    68   4e-10
UniRef50_Q15W58 Cluster: Short-chain dehydrogenase/reductase SDR...    67   5e-10
UniRef50_Q1DI24 Cluster: Putative uncharacterized protein; n=1; ...    67   5e-10
UniRef50_A7DQK3 Cluster: Short-chain dehydrogenase/reductase SDR...    67   5e-10
UniRef50_Q3WGH4 Cluster: Short-chain dehydrogenase/reductase SDR...    67   6e-10
UniRef50_A5P2I8 Cluster: Short-chain dehydrogenase/reductase SDR...    67   6e-10
UniRef50_Q0UC34 Cluster: Putative uncharacterized protein; n=1; ...    67   6e-10
UniRef50_Q05016 Cluster: Uncharacterized oxidoreductase YMR226C;...    67   6e-10
UniRef50_Q8R940 Cluster: Dehydrogenases with different specifici...    66   8e-10
UniRef50_Q0U516 Cluster: Putative uncharacterized protein; n=1; ...    66   8e-10
UniRef50_Q88T72 Cluster: Short-chain dehydrogenase/oxidoreductas...    66   1e-09
UniRef50_A4RIP2 Cluster: Putative uncharacterized protein; n=1; ...    66   1e-09
UniRef50_A4QXZ6 Cluster: Putative uncharacterized protein; n=3; ...    66   1e-09
UniRef50_A4S6P3 Cluster: Predicted protein; n=2; Ostreococcus|Re...    66   1e-09
UniRef50_Q2H7T1 Cluster: Putative uncharacterized protein; n=1; ...    66   1e-09
UniRef50_Q022W9 Cluster: Short-chain dehydrogenase/reductase SDR...    65   2e-09
UniRef50_A2FH32 Cluster: Oxidoreductase, short chain dehydrogena...    65   2e-09
UniRef50_A3TMZ8 Cluster: Putative short chain dehydrogenase; n=1...    65   3e-09
UniRef50_Q2UTZ6 Cluster: Dehydrogenases with different specifici...    65   3e-09
UniRef50_A4RIR1 Cluster: Putative uncharacterized protein; n=1; ...    65   3e-09
UniRef50_A7EEQ4 Cluster: Putative uncharacterized protein; n=1; ...    64   3e-09
UniRef50_Q5AF74 Cluster: Putative uncharacterized protein SCD99;...    64   5e-09
UniRef50_A5DVP7 Cluster: Putative uncharacterized protein; n=3; ...    64   5e-09
UniRef50_UPI000049978B Cluster: short chain dehydrogenase family...    64   6e-09
UniRef50_A4RS22 Cluster: Predicted protein; n=2; Ostreococcus|Re...    64   6e-09
UniRef50_Q5C2D2 Cluster: SJCHGC07738 protein; n=1; Schistosoma j...    63   8e-09
UniRef50_Q0V6Q2 Cluster: Putative uncharacterized protein; n=1; ...    63   8e-09
UniRef50_A1SG11 Cluster: Short-chain dehydrogenase/reductase SDR...    63   1e-08
UniRef50_Q70L71 Cluster: NADPH-protochlorophyllide oxidoreductas...    63   1e-08
UniRef50_Q4SC59 Cluster: Chromosome 14 SCAF14660, whole genome s...    62   1e-08
UniRef50_Q9WWC0 Cluster: AtsC; n=3; Agrobacterium tumefaciens|Re...    62   1e-08
UniRef50_Q7D8X9 Cluster: Oxidoreductase, short-chain dehydrogena...    62   1e-08
UniRef50_Q1GNI9 Cluster: Short-chain dehydrogenase/reductase SDR...    62   1e-08
UniRef50_A5CR50 Cluster: Putative short chain dehydrogenase/oxid...    62   1e-08
UniRef50_O13822 Cluster: Short chain dehydrogenase; n=1; Schizos...    62   1e-08
UniRef50_UPI000023EAB8 Cluster: hypothetical protein FG07727.1; ...    62   2e-08
UniRef50_Q4RQU5 Cluster: Chromosome 2 SCAF15004, whole genome sh...    62   2e-08
UniRef50_Q0UK52 Cluster: Putative uncharacterized protein; n=1; ...    62   2e-08
UniRef50_Q5KZI9 Cluster: Dehydrogenase; n=5; Bacilli|Rep: Dehydr...    62   2e-08
UniRef50_Q0SFE0 Cluster: Probable short chain dehydrogenase; n=1...    62   2e-08
UniRef50_Q0S388 Cluster: Possible dehydrogenase; n=16; Corynebac...    62   2e-08
UniRef50_Q2HC60 Cluster: Putative uncharacterized protein; n=2; ...    62   2e-08
UniRef50_A4UBW3 Cluster: Putative uncharacterized protein; n=1; ...    62   2e-08
UniRef50_Q2FUH8 Cluster: Short-chain dehydrogenase/reductase SDR...    62   2e-08
UniRef50_A3Y6H5 Cluster: Short chain dehydrogenase; n=4; Bacteri...    61   3e-08
UniRef50_A0Z4N6 Cluster: Short chain dehydrogenase; n=2; Bacteri...    61   3e-08
UniRef50_Q9XYN2 Cluster: Antennal-specific short-chain dehydroge...    61   3e-08
UniRef50_Q039Y3 Cluster: Short-chain alcohol dehydrogenase; n=1;...    61   4e-08
UniRef50_Q0V4E3 Cluster: Predicted protein; n=1; Phaeosphaeria n...    61   4e-08
UniRef50_Q97DL2 Cluster: 3-oxoacyl-acyl carrier protein reductas...    60   6e-08
UniRef50_Q0URP7 Cluster: Putative uncharacterized protein; n=1; ...    60   6e-08
UniRef50_Q740T8 Cluster: Putative uncharacterized protein; n=1; ...    60   7e-08
UniRef50_Q3ACJ4 Cluster: Oxidoreductase, short chain dehydrogena...    60   7e-08
UniRef50_A4ABL9 Cluster: Short-chain dehydrogenase/reductase SDR...    60   7e-08
UniRef50_Q015J2 Cluster: POR_DAUCA Protochlorophyllide reductase...    60   7e-08
UniRef50_A7SZ09 Cluster: Predicted protein; n=2; Nematostella ve...    60   7e-08
UniRef50_Q62GY7 Cluster: Oxidoreductase, short-chain dehydrogena...    60   1e-07
UniRef50_A3YE37 Cluster: Short-chain dehydrogenase/reductase SDR...    60   1e-07
UniRef50_Q2H363 Cluster: Putative uncharacterized protein; n=2; ...    60   1e-07
UniRef50_Q5YXH8 Cluster: Putative short chain dehydrogenase; n=1...    59   1e-07
UniRef50_A7CT24 Cluster: Short-chain dehydrogenase/reductase SDR...    59   1e-07
UniRef50_A3GFG2 Cluster: Predicted protein; n=2; Saccharomycetac...    59   1e-07
UniRef50_A7DSF0 Cluster: Short-chain dehydrogenase/reductase SDR...    59   1e-07
UniRef50_Q0SGM5 Cluster: 3-oxoacyl-[acyl-carrier-protein] reduct...    59   2e-07
UniRef50_Q08U98 Cluster: NAD dependent epimerase/dehydratase fam...    59   2e-07
UniRef50_Q9Y140 Cluster: CG7601-PA; n=5; Endopterygota|Rep: CG76...    59   2e-07
UniRef50_A6RTJ1 Cluster: Putative uncharacterized protein; n=1; ...    59   2e-07
UniRef50_UPI0000E46364 Cluster: PREDICTED: hypothetical protein;...    58   2e-07
UniRef50_Q9KCQ9 Cluster: Oxidoreductase; n=10; Firmicutes|Rep: O...    58   2e-07
UniRef50_A7IEU0 Cluster: Short-chain dehydrogenase/reductase SDR...    58   2e-07
UniRef50_Q1E2C3 Cluster: Putative uncharacterized protein; n=1; ...    58   2e-07
UniRef50_Q6LLA8 Cluster: Putative uncharacterized protein MT0455...    58   3e-07
UniRef50_Q46UH5 Cluster: Short-chain dehydrogenase/reductase SDR...    58   3e-07
UniRef50_Q592T9 Cluster: Putative uncharacterized protein; n=1; ...    58   3e-07
UniRef50_Q4QAF0 Cluster: Short chain dehydrogenase/reductase, pu...    58   3e-07
UniRef50_P66779 Cluster: Uncharacterized oxidoreductase Rv1543/M...    58   3e-07
UniRef50_Q6MHI6 Cluster: Short chain dehydrogenase; n=1; Bdellov...    58   4e-07
UniRef50_Q2JY74 Cluster: Oxidoreductase, short chain dehydrogena...    58   4e-07
UniRef50_Q1IPJ3 Cluster: Short-chain dehydrogenase/reductase SDR...    58   4e-07
UniRef50_A0M1K4 Cluster: Short-chain dehydrogenase/reductase fam...    58   4e-07
UniRef50_Q1VPL8 Cluster: Oxidoreductase, short chain dehydrogena...    57   5e-07
UniRef50_A6CQ13 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    57   5e-07
UniRef50_A2WII1 Cluster: Short-chain alcohol dehydrogenase; n=8;...    57   5e-07
UniRef50_A0NRY8 Cluster: Short-chain dehydrogenase/reductase SDR...    57   5e-07
UniRef50_A2YPN0 Cluster: Putative uncharacterized protein; n=3; ...    57   5e-07
UniRef50_Q7SGM6 Cluster: Putative uncharacterized protein NCU080...    57   5e-07
UniRef50_A4QYV9 Cluster: Putative uncharacterized protein; n=1; ...    57   5e-07
UniRef50_A2Q9W2 Cluster: Similarity to beta-ketoacyl reductase r...    57   5e-07
UniRef50_A1DEA7 Cluster: Oxidoreductase, short chain dehydrogena...    57   5e-07
UniRef50_Q5V3M2 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    57   5e-07
UniRef50_UPI0000F1D429 Cluster: PREDICTED: hypothetical protein;...    57   7e-07
UniRef50_Q128L4 Cluster: Short-chain dehydrogenase/reductase SDR...    57   7e-07
UniRef50_Q11E37 Cluster: Short-chain dehydrogenase/reductase SDR...    57   7e-07
UniRef50_A1UD76 Cluster: Short-chain dehydrogenase/reductase SDR...    57   7e-07
UniRef50_UPI00015B49F3 Cluster: PREDICTED: similar to oxidoreduc...    56   9e-07
UniRef50_UPI0000F1D96F Cluster: PREDICTED: hypothetical protein;...    56   9e-07
UniRef50_UPI000065F6AD Cluster: Homolog of Homo sapiens "Dehydro...    56   9e-07
UniRef50_Q83BJ5 Cluster: Oxidoreductase, short chain dehydrogena...    56   9e-07
UniRef50_O07230 Cluster: PROBABLE DEHYDROGENASE/REDUCTASE; n=7; ...    56   9e-07
UniRef50_Q4AH64 Cluster: Dehydrogenases with different specifici...    56   9e-07
UniRef50_Q1DCG1 Cluster: Oxidoreductase, short-chain dehydrogena...    56   9e-07
UniRef50_A0QXD6 Cluster: L-xylulose reductase; n=2; Actinomyceta...    56   9e-07
UniRef50_Q4WFD6 Cluster: Short-chain dehydrogenase/reductase fam...    56   9e-07
UniRef50_Q2GXX0 Cluster: Putative uncharacterized protein; n=1; ...    56   9e-07
UniRef50_UPI0000E465C5 Cluster: PREDICTED: similar to MGC80593 p...    56   1e-06
UniRef50_A7H6A6 Cluster: Short-chain dehydrogenase/reductase SDR...    56   1e-06
UniRef50_A6SY22 Cluster: Oxidoreductase, short chain dehydrogena...    56   1e-06
UniRef50_A6GRW7 Cluster: Short-chain dehydrogenase/reductase SDR...    56   1e-06
UniRef50_A3ZNA3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    56   1e-06
UniRef50_A0Y8J3 Cluster: Short chain dehydrogenase; n=1; marine ...    56   1e-06
UniRef50_Q019W6 Cluster: Short-chain dehydrogenase/reductase; n=...    56   1e-06
UniRef50_Q9VYU9 Cluster: CG9360-PA; n=12; Diptera|Rep: CG9360-PA...    56   1e-06
UniRef50_Q0U2A1 Cluster: Putative uncharacterized protein; n=1; ...    56   1e-06
UniRef50_Q55922 Cluster: Slr0315 protein; n=2; Bacteria|Rep: Slr...    56   2e-06
UniRef50_Q3WFB3 Cluster: Short-chain dehydrogenase/reductase SDR...    56   2e-06
UniRef50_Q1ITR9 Cluster: Short-chain dehydrogenase/reductase SDR...    56   2e-06
UniRef50_Q4YKD8 Cluster: Putative uncharacterized protein; n=2; ...    56   2e-06
UniRef50_Q15ER8 Cluster: U2 snRNP splicing factor small subunit-...    56   2e-06
UniRef50_Q2GZT7 Cluster: Putative uncharacterized protein; n=1; ...    56   2e-06
UniRef50_Q3IT50 Cluster: Predicted dehydrogenase; n=1; Natronomo...    56   2e-06
UniRef50_UPI0000586026 Cluster: PREDICTED: similar to Retinol de...    55   2e-06
UniRef50_Q2W6X2 Cluster: Dehydrogenase with different specificit...    55   2e-06
UniRef50_Q2JF82 Cluster: Short-chain dehydrogenase/reductase SDR...    55   2e-06
UniRef50_Q2IQ98 Cluster: Short-chain dehydrogenase/reductase SDR...    55   2e-06
UniRef50_Q0ANJ9 Cluster: Short-chain dehydrogenase/reductase SDR...    55   2e-06
UniRef50_A6CL44 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    55   2e-06
UniRef50_A5WBL2 Cluster: Short-chain dehydrogenase/reductase SDR...    55   2e-06
UniRef50_A4BH63 Cluster: Short-chain alcohol dehydrogenase-like ...    55   2e-06
UniRef50_A3KJN1 Cluster: Putative 3-oxoacyl-acyl-carrier protein...    55   2e-06
UniRef50_Q16ZY5 Cluster: Short-chain dehydrogenase; n=1; Aedes a...    55   2e-06
UniRef50_A6SP29 Cluster: Putative uncharacterized protein; n=1; ...    55   2e-06
UniRef50_Q81WX9 Cluster: 3-oxoacyl-(Acyl-carrier-protein) reduct...    55   3e-06
UniRef50_Q5LDH2 Cluster: Putative 2,5-dichloro-2,5-cyclohexadien...    55   3e-06
UniRef50_Q39NM3 Cluster: Short-chain dehydrogenase/reductase SDR...    55   3e-06
UniRef50_O54125 Cluster: Possible oxidoreductase; n=2; Actinomyc...    55   3e-06
UniRef50_A6W2Y5 Cluster: Short-chain dehydrogenase/reductase SDR...    55   3e-06
UniRef50_A3M7D6 Cluster: Oxidoreductase short-chain dehydrogenas...    55   3e-06
UniRef50_A1SG64 Cluster: Short-chain dehydrogenase/reductase SDR...    55   3e-06
UniRef50_A1BIN1 Cluster: Short-chain dehydrogenase/reductase SDR...    55   3e-06
UniRef50_O15744 Cluster: PksB; n=2; Dictyostelium discoideum|Rep...    55   3e-06
UniRef50_Q0ULJ5 Cluster: Putative uncharacterized protein; n=2; ...    55   3e-06
UniRef50_A6QZL7 Cluster: Putative uncharacterized protein; n=1; ...    55   3e-06
UniRef50_Q5V0V4 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    55   3e-06
UniRef50_Q92BC9 Cluster: Lin1621 protein; n=1; Listeria innocua|...    54   4e-06
UniRef50_Q3IKU0 Cluster: Putative 3-oxoacyl-[acyl-carrier protei...    54   4e-06
UniRef50_Q1NHA6 Cluster: Putative beta-ketoacyl reductase; n=1; ...    54   4e-06
UniRef50_Q1ILJ4 Cluster: Short-chain dehydrogenase/reductase SDR...    54   4e-06
UniRef50_Q1AU84 Cluster: Short-chain dehydrogenase/reductase SDR...    54   4e-06
UniRef50_Q081K4 Cluster: Short-chain dehydrogenase/reductase SDR...    54   4e-06
UniRef50_A1SC90 Cluster: Short-chain dehydrogenase/reductase SDR...    54   4e-06
UniRef50_Q4WIW1 Cluster: Short-chain dehydrogenase/reductase fam...    54   4e-06
UniRef50_Q2UUQ7 Cluster: Dehydrogenases with different specifici...    54   4e-06
UniRef50_P39071 Cluster: 2,3-dihydro-2,3-dihydroxybenzoate dehyd...    54   4e-06
UniRef50_Q9PCQ2 Cluster: 2,5-dichloro-2,5-cyclohexadiene-1,4-dio...    54   5e-06
UniRef50_Q5LMX2 Cluster: 20-beta-hydroxysteroid dehydrogenase, p...    54   5e-06
UniRef50_Q2IEG2 Cluster: Short-chain dehydrogenase/reductase SDR...    54   5e-06
UniRef50_Q0F3M2 Cluster: Short chain dehydrogenase; n=1; Maripro...    54   5e-06
UniRef50_A3WGJ0 Cluster: Short-chain dehydrogenase/reductase SDR...    54   5e-06
UniRef50_A1SJM6 Cluster: Short-chain dehydrogenase/reductase SDR...    54   5e-06
UniRef50_Q5CAF5 Cluster: Neomenthol dehydrogenase; n=5; core eud...    54   5e-06
UniRef50_Q57YP3 Cluster: Short-chain dehydrogenase, putative; n=...    54   5e-06
UniRef50_A7S945 Cluster: Predicted protein; n=1; Nematostella ve...    54   5e-06
UniRef50_A2QGA4 Cluster: Remark: the human PRO polypeptides have...    54   5e-06
UniRef50_Q07530 Cluster: Uncharacterized oxidoreductase YDL114W;...    54   5e-06
UniRef50_Q930M2 Cluster: Putative; n=4; Bacteria|Rep: Putative -...    54   6e-06
UniRef50_Q1YZB6 Cluster: Short chain dehydrogenase; n=6; Gammapr...    54   6e-06
UniRef50_Q1FP38 Cluster: Short-chain dehydrogenase/reductase SDR...    54   6e-06
UniRef50_Q0GL61 Cluster: Short-chain dehydrogenase; n=3; Lactoba...    54   6e-06
UniRef50_Q0GJJ3 Cluster: 11-beta-hydroxysteroid dehydrogenase-li...    54   6e-06
UniRef50_Q0D3V3 Cluster: Os07g0664100 protein; n=2; Oryza sativa...    54   6e-06
UniRef50_Q9W3K9 Cluster: CG2254-PA; n=4; Sophophora|Rep: CG2254-...    54   6e-06
UniRef50_Q22DT5 Cluster: Oxidoreductase, short chain dehydrogena...    54   6e-06
UniRef50_A3FQ00 Cluster: Putative uncharacterized protein; n=1; ...    54   6e-06
UniRef50_Q4P1P4 Cluster: Putative uncharacterized protein; n=1; ...    54   6e-06
UniRef50_P46331 Cluster: Uncharacterized oxidoreductase yxbG; n=...    54   6e-06
UniRef50_Q81M93 Cluster: Oxidoreductase, short-chain dehydrogena...    53   8e-06
UniRef50_Q6MNE1 Cluster: Oxidoreductase precursor; n=3; Bacteria...    53   8e-06
UniRef50_Q44MJ4 Cluster: Short-chain dehydrogenase/reductase SDR...    53   8e-06
UniRef50_A7C8U0 Cluster: Short-chain dehydrogenase/reductase SDR...    53   8e-06
UniRef50_A6WB74 Cluster: Short-chain dehydrogenase/reductase SDR...    53   8e-06
UniRef50_A6GUI4 Cluster: Short-chain dehydrogenase/reductase fam...    53   8e-06
UniRef50_A4GHX2 Cluster: Short-chain dehydrogenase/reductase; n=...    53   8e-06
UniRef50_A4FA51 Cluster: Light-dependent protochlorophyllide red...    53   8e-06
UniRef50_A3JWC2 Cluster: Dehydrogenase; n=1; Rhodobacterales bac...    53   8e-06
UniRef50_A4R876 Cluster: Putative uncharacterized protein; n=1; ...    53   8e-06
UniRef50_A2QT81 Cluster: Function: mouse WOX1 is an enhancer of ...    53   8e-06
UniRef50_UPI0000E4700A Cluster: PREDICTED: hypothetical protein,...    53   1e-05
UniRef50_Q8F3S6 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    53   1e-05
UniRef50_Q5KZB7 Cluster: 3-oxoacyl-[acyl-carrier protein] reduct...    53   1e-05
UniRef50_Q393N0 Cluster: Short-chain dehydrogenase/reductase SDR...    53   1e-05
UniRef50_Q2S401 Cluster: Oxidoreductase, short chain dehydrogena...    53   1e-05
UniRef50_Q6Q236 Cluster: Putative 3-oxoacyl-(Acyl-carrier protei...    53   1e-05
UniRef50_Q2N2P3 Cluster: 3-oxoacyl-carrier-protein reductase; n=...    53   1e-05
UniRef50_Q0TU60 Cluster: Oxidoreductase, short-chain dehydrogena...    53   1e-05
UniRef50_A5V6Z5 Cluster: Short-chain dehydrogenase/reductase SDR...    53   1e-05
UniRef50_A5V384 Cluster: Short-chain dehydrogenase/reductase SDR...    53   1e-05
UniRef50_A1ZGN7 Cluster: Short-chain dehydrogenase/reductase SDR...    53   1e-05
UniRef50_A1WNV5 Cluster: Short-chain dehydrogenase/reductase SDR...    53   1e-05
UniRef50_A0KBT1 Cluster: Short-chain dehydrogenase/reductase SDR...    53   1e-05
UniRef50_A0JTT9 Cluster: Short-chain dehydrogenase/reductase SDR...    53   1e-05
UniRef50_Q4DA05 Cluster: Short chain dehydrogenase/reductase, pu...    53   1e-05
UniRef50_A0E1K9 Cluster: Chromosome undetermined scaffold_73, wh...    53   1e-05
UniRef50_Q6CFW0 Cluster: Yarrowia lipolytica chromosome B of str...    53   1e-05
UniRef50_A6S6K4 Cluster: Putative uncharacterized protein; n=1; ...    53   1e-05
UniRef50_A6QU30 Cluster: Predicted protein; n=1; Ajellomyces cap...    53   1e-05
UniRef50_A2QGB2 Cluster: Contig An03c0070, complete genome; n=1;...    53   1e-05
UniRef50_Q9HRV8 Cluster: Oxidoreductase homolog; n=1; Halobacter...    53   1e-05
UniRef50_Q6MAU7 Cluster: Putative blue fluorescent protein; n=1;...    52   1e-05
UniRef50_Q6F7B8 Cluster: Fatty acyl-CoA reductase; n=6; Moraxell...    52   1e-05
UniRef50_Q5FKH2 Cluster: Oxidoreductase, short chaindehydrogenas...    52   1e-05
UniRef50_Q124X5 Cluster: Male sterility-like; n=9; Proteobacteri...    52   1e-05
UniRef50_Q0VL04 Cluster: Oxidoreductase, putative; n=1; Alcanivo...    52   1e-05
UniRef50_Q0B254 Cluster: Short-chain dehydrogenase/reductase SDR...    52   1e-05
UniRef50_A6BFV0 Cluster: Putative uncharacterized protein; n=1; ...    52   1e-05
UniRef50_A5FDC2 Cluster: Short-chain dehydrogenase/reductase SDR...    52   1e-05
UniRef50_A3ZQM3 Cluster: 3-oxoacyl-(Acyl-carrier protein) reduct...    52   1e-05
UniRef50_A1SKT4 Cluster: Male sterility C-terminal domain; n=1; ...    52   1e-05
UniRef50_A1SHR0 Cluster: Short-chain dehydrogenase/reductase SDR...    52   1e-05
UniRef50_A1SCT9 Cluster: Short-chain dehydrogenase/reductase SDR...    52   1e-05
UniRef50_Q0DM18 Cluster: Os03g0833100 protein; n=5; Oryza sativa...    52   1e-05

>UniRef50_UPI00015B5303 Cluster: PREDICTED: similar to AT09608p;
           n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
           AT09608p - Nasonia vitripennis
          Length = 345

 Score =  303 bits (744), Expect = 4e-81
 Identities = 142/301 (47%), Positives = 189/301 (62%), Gaps = 1/301 (0%)

Query: 9   RDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRD 68
           +DY  G  Y+ + +  ++ +I+TGAN+GIGK  A D AKR A+V MACRD+ KCE  R+ 
Sbjct: 25  KDYNGGKKYEGNEKLTDKVVIVTGANTGIGKEVAHDLAKREARVIMACRDMFKCETARKQ 84

Query: 69  IVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFET 128
           IV++T NKYVYCR CDLAS  SIR+FV  FK E   LH+L+NNAGVM  PK  TK+G E 
Sbjct: 85  IVIDTKNKYVYCRKCDLASQESIRDFVKLFKKEHQKLHILINNAGVMRCPKSQTKEGIEM 144

Query: 129 QLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQ 188
           QLGV                K              H RG+I+  DLN  ENYD +AAY+Q
Sbjct: 145 QLGVNHMGHFLLTNLLLDTLKASAPARIINVSSLAHARGKINMYDLNSDENYDPAAAYAQ 204

Query: 189 SKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKS-VTRFFIYPLFWPFMK 247
           SKLAN++F  EL +RL GTGV   AV PG+VDT++TRHM    S  +  F+ PL WPF++
Sbjct: 205 SKLANVMFTTELAKRLKGTGVTVNAVHPGIVDTELTRHMGYYTSGFSAIFLKPLIWPFIR 264

Query: 248 KPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLDEH 307
            P+ G QT+++AAL P+L+   G Y+ + K+ + +  A+  +L +WLW+ SE WT L   
Sbjct: 265 TPKQGAQTILYAALSPELEKVTGQYFSNCKREDVNPIAEKEDLLEWLWKTSEKWTHLSSR 324

Query: 308 K 308
           K
Sbjct: 325 K 325


>UniRef50_Q4QQ95 Cluster: IP09970p; n=6; Endopterygota|Rep: IP09970p
           - Drosophila melanogaster (Fruit fly)
          Length = 332

 Score =  250 bits (613), Expect = 3e-65
 Identities = 124/297 (41%), Positives = 170/297 (57%), Gaps = 1/297 (0%)

Query: 9   RDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRD 68
           R Y  G  + +      +  I+TG N+G+GK    + A+RGA V+MACR+ +K E  RR+
Sbjct: 34  RLYMQGGKFRKQTDETGKVAIVTGGNTGLGKETVMELARRGATVYMACRNKEKVERARRE 93

Query: 69  IVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFET 128
           IV ET N  V+ R CDL+S  SIR+F   FK E+  LH+L+NNAGV   P  +TK+GFE 
Sbjct: 94  IVKETGNSNVFSRECDLSSLDSIRKFAENFKKEQRVLHILINNAGVFWEPHRLTKEGFEM 153

Query: 129 QLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQ 188
            LGV                +              H+RG+I   D+N S+ YD   AY Q
Sbjct: 154 HLGVNHIGHFLLTNLLLGVLERSAPSRVVVVASRAHERGQIKVDDINSSDFYDEGVAYCQ 213

Query: 189 SKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKS-VTRFFIYPLFWPFMK 247
           SKLAN+LF REL +RL GTGV   A++PG+ DT+I R+M   ++   +  + PL W  MK
Sbjct: 214 SKLANILFTRELAKRLEGTGVTVNALNPGIADTEIARNMIFFQTKFAQTILRPLLWAVMK 273

Query: 248 KPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
            P+ G QT ++AALDP L+  +G Y+ D   A  +  A D ++AQWLW  SE W K+
Sbjct: 274 TPKNGAQTTLYAALDPDLERVSGQYFSDCALAPVAPAALDDQMAQWLWAQSEKWAKI 330


>UniRef50_Q16J02 Cluster: Short-chain dehydrogenase; n=2;
           Diptera|Rep: Short-chain dehydrogenase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 338

 Score =  237 bits (581), Expect = 2e-61
 Identities = 122/306 (39%), Positives = 171/306 (55%), Gaps = 4/306 (1%)

Query: 1   MFVSFLFNRDYYSGPPY-DRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDV 59
           +F    F R ++ G  + ++ +R D + +IITGANSGIGK  A + AKRGA+V+M CRD 
Sbjct: 35  IFAFVYFVRKFFQGGQFKNKDIRLDAKVVIITGANSGIGKETAIECAKRGARVYMGCRDA 94

Query: 60  KKCEEQRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPK 119
            + E+ R++I+ ++ ++ V+    DLAS  SIR FV  F   E  LHVL+NNAGVM  PK
Sbjct: 95  NRMEKARQEILDKSGSQNVFGLELDLASFDSIRNFVRTFLSMERRLHVLINNAGVMACPK 154

Query: 120 GVTKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN 179
             TKDGFE   GV                K              H+ GRI K D+N  ++
Sbjct: 155 EYTKDGFEMHFGVNHLGHFYLTNLLVDVLKRTAPSRIVTVSSLGHKWGRIDKDDINSEKD 214

Query: 180 YDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIY 239
           Y    AY QSKL N+LF+R L +RL GTG+ T  + PG V+T++TR+ +    +      
Sbjct: 215 YREWGAYMQSKLCNILFSRHLAKRLRGTGIHTYCLHPGTVNTELTRYQNRCMMIA---AK 271

Query: 240 PLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
           PL W F K  + G QT ++ A++P +    G YY D K  EP   A+D  +A+WLW +SE
Sbjct: 272 PLLWVFFKSAKSGAQTTLYCAMEPTIAGDTGKYYSDCKLKEPEPHAKDDAMAEWLWNISE 331

Query: 300 AWTKLD 305
             T L+
Sbjct: 332 KLTGLN 337


>UniRef50_Q9W404 Cluster: CG3842-PA, isoform A; n=11; Coelomata|Rep:
           CG3842-PA, isoform A - Drosophila melanogaster (Fruit
           fly)
          Length = 406

 Score =  215 bits (524), Expect = 2e-54
 Identities = 118/296 (39%), Positives = 158/296 (53%), Gaps = 10/296 (3%)

Query: 9   RDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRD 68
           R    GP Y ++ R D + +I+TG N+GIGK    + AKRGA+V+MACRD  +CE  R D
Sbjct: 58  RKCIQGPAYRKANRIDGKVVIVTGCNTGIGKETVLELAKRGARVYMACRDPGRCEAARLD 117

Query: 69  IVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFET 128
           I+  + N+ ++ R  DL S  S+R FV RFK EE  L +L+NNAGVM  P+ +T DGFE 
Sbjct: 118 IMDRSRNQQLFNRTLDLGSLQSVRNFVERFKAEESRLDILINNAGVMACPRTLTADGFEQ 177

Query: 129 QLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDA-SAAYS 187
           Q GV                K              H  GRI+++DL   +NY     AYS
Sbjct: 178 QFGVNHLGHFLLTNLLLDRLKHSSPSRIVVVSSAAHLFGRINREDLMSEKNYSKFFGAYS 237

Query: 188 QSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMS----MMKSVTRFFIYPLFW 243
           QSKLAN+LF  +L   L  TGV      PG+V T+I RH S    M  ++ +  +Y    
Sbjct: 238 QSKLANILFTLKLSTILKDTGVTVNCCHPGVVRTEINRHFSGPGWMKTALQKGSLY---- 293

Query: 244 PFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
            F K P+ G QT +  ALDP+L+   G YY D  +       ++ + A WLWR SE
Sbjct: 294 -FFKTPKAGAQTQLRLALDPQLEGSTGGYYSDCMRWPLFPWVRNMQTADWLWRESE 348


>UniRef50_Q8NBN7 Cluster: Retinol dehydrogenase 13; n=19;
           Deuterostomia|Rep: Retinol dehydrogenase 13 - Homo
           sapiens (Human)
          Length = 331

 Score =  215 bits (524), Expect = 2e-54
 Identities = 114/292 (39%), Positives = 159/292 (54%), Gaps = 2/292 (0%)

Query: 9   RDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRD 68
           +DY +G           +T+I+TGAN+GIGK  A + A+RG  + +ACRD++KCE   +D
Sbjct: 22  KDYVTGGACPSKATIPGKTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKD 81

Query: 69  IVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFET 128
           I  ET N +V  R  DLAS  SIREF A+   EE  + +L+NNAGVM  P   T+DGFE 
Sbjct: 82  IRGETLNHHVNARHLDLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEM 141

Query: 129 QLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLN-MSENYDASAAYS 187
           Q GV                K              H  G I   DLN  +  Y+  AAY 
Sbjct: 142 QFGVNHLGHFLLTNLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYC 201

Query: 188 QSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSV-TRFFIYPLFWPFM 246
           QSKLA +LF +EL RRL G+GV   A+ PG+  T++ RH  +  S  +   + P+FW  +
Sbjct: 202 QSKLAIVLFTKELSRRLQGSGVTVNALHPGVARTELGRHTGIHGSTFSSTTLGPIFWLLV 261

Query: 247 KKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           K PE+  Q   + A+  +L D +G Y+  +K+  P+ EA+D E+A+ LW  S
Sbjct: 262 KSPELAAQPSTYLAVAEELADVSGKYFDGLKQKAPAPEAEDEEVARRLWAES 313


>UniRef50_Q8TC12 Cluster: Retinol dehydrogenase 11; n=49;
           Coelomata|Rep: Retinol dehydrogenase 11 - Homo sapiens
           (Human)
          Length = 318

 Score =  212 bits (517), Expect = 1e-53
 Identities = 114/279 (40%), Positives = 160/279 (57%), Gaps = 5/279 (1%)

Query: 20  SVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVY 79
           +V+   + +++TGAN+GIGK  AK+ A+RGA+V++ACRDV+K E   ++I   T N+ V 
Sbjct: 36  TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVL 95

Query: 80  CRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXX 139
            R  DL+ T SIR F   F  EE HLHVL+NNAGVM  P   T DGFE  +GV       
Sbjct: 96  VRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFL 155

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                    K              H  GRIH  +L   + Y+A  AY  SKLAN+LF +E
Sbjct: 156 LTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILFTQE 215

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
           L RRL G+GV T +V PG V +++ RH S M+     +++ LF  F+K P+ G QT +H 
Sbjct: 216 LARRLKGSGVTTYSVHPGTVQSELVRHSSFMR-----WMWWLFSFFIKTPQQGAQTSLHC 270

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           AL   L+  +G+++ D   A  S +A++  +A+ LW VS
Sbjct: 271 ALTEGLEILSGNHFSDCHVAWVSAQARNETIARRLWDVS 309


>UniRef50_Q4T7M3 Cluster: Chromosome undetermined SCAF8083, whole
           genome shotgun sequence; n=4; Tetraodontidae|Rep:
           Chromosome undetermined SCAF8083, whole genome shotgun
           sequence - Tetraodon nigroviridis (Green puffer)
          Length = 357

 Score =  210 bits (514), Expect = 3e-53
 Identities = 111/277 (40%), Positives = 153/277 (55%), Gaps = 4/277 (1%)

Query: 22  RADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCR 81
           R D +T+IITGAN+GIGK  A+D A+RGA++ MACRD+++ EE R DI+ +T N+ V  R
Sbjct: 76  RLDGKTVIITGANTGIGKETARDLARRGARIVMACRDLERAEEARADILEDTGNENVVIR 135

Query: 82  PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX 141
             DL+ T SI+ F      EE  +++L+NNAG+M  P   T DGFE QLGV         
Sbjct: 136 KLDLSDTKSIKAFADLVNKEEKQVNILINNAGIMMCPHSKTADGFEMQLGVNHLGHFLLT 195

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELG 201
                  +              H    +   DLN   +YD   AY QSKLAN+LFAR L 
Sbjct: 196 YLLLDLIQRSAPARVVVVASVAHTWTGLRLDDLNSERSYDTMKAYGQSKLANVLFARSLA 255

Query: 202 RRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAAL 261
           +RL GTGV+  ++ PG+V +D+ RH      +       +F  F K    G QT V+ A+
Sbjct: 256 KRLQGTGVSVFSLHPGVVQSDLWRHQHQCIQMA----VKIFRIFTKTTVEGAQTTVYCAV 311

Query: 262 DPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           +P L+  +G Y+ D   A  S+ A D +LAQ LW +S
Sbjct: 312 EPHLESQSGGYFSDCAPATCSRAASDDDLAQKLWEIS 348



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 25/66 (37%), Positives = 38/66 (57%), Gaps = 4/66 (6%)

Query: 208 GVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKLKD 267
           GV+T +VDPG+VDT+ITRH   ++ + RF     F   ++ P  G  T V+  + P+ + 
Sbjct: 2   GVSTYSVDPGMVDTEITRH--FIRPLARF--TKTFGFLIRTPAEGAYTTVYCVVTPESQL 57

Query: 268 CAGDYY 273
             G YY
Sbjct: 58  RTGGYY 63


>UniRef50_Q0P435 Cluster: Zgc:153441; n=7; Clupeocephala|Rep:
           Zgc:153441 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 336

 Score =  204 bits (497), Expect = 3e-51
 Identities = 111/297 (37%), Positives = 161/297 (54%), Gaps = 1/297 (0%)

Query: 3   VSFLFNRDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKC 62
           +S L  R + SG      VR D +T++ITGAN+GIGK  A+D A+RGA+V MACRD+ K 
Sbjct: 30  ISLLLLRRWISGGVCRCRVRLDGKTVVITGANTGIGKETARDMARRGARVVMACRDLSKA 89

Query: 63  EEQRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVT 122
           E+   +I   T N  +  R  +LAS  S+R+F  ++   E  L +L+NNAGVM  PK +T
Sbjct: 90  EKAAAEIRRSTGNADIVVRHLNLASLHSVRQFAHQYTATEDRLDILINNAGVMMCPKSLT 149

Query: 123 KDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE-NYD 181
           +DG+ETQ  V                K              H+ G+IH  DLN ++  YD
Sbjct: 150 EDGYETQFAVNHLGHFLLTVLLLDMLKKSSPSRVINVSSITHKGGKIHFDDLNFNKAPYD 209

Query: 182 ASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPL 241
           +  +Y QSKLANLLF REL RR+ G+GV+  ++ PG++ T++ R++     +    +   
Sbjct: 210 SLVSYRQSKLANLLFTRELARRIKGSGVSVFSLHPGVIRTELGRYVQTRHPLLSGLLSIP 269

Query: 242 FWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
               MK P  G QT ++ A    L+  +G Y+ D    EP+ E +D   A  LW +S
Sbjct: 270 ALLLMKTPYQGAQTSIYCATADGLEIHSGCYFSDCALKEPAPEGKDDLAALRLWEIS 326


>UniRef50_Q6NY49 Cluster: LOC407663 protein; n=23; Eumetazoa|Rep:
           LOC407663 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 331

 Score =  200 bits (487), Expect = 5e-50
 Identities = 108/296 (36%), Positives = 160/296 (54%), Gaps = 2/296 (0%)

Query: 9   RDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRD 68
           R + +G       R + +T++ITG N+GIGK  A D AKRGA+V +ACRD+ +  +   +
Sbjct: 37  RRWLAGGVCRSKARLNGKTVLITGGNTGIGKETAVDMAKRGARVILACRDMSRAHKAAEE 96

Query: 69  IVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFET 128
           I   + N+ V  +  DLAS  S+R+ V   +  E  L +L+NNAGVM  PK  T +GFE 
Sbjct: 97  IRKRSGNENVTVKMLDLASLQSVRDLVKDVQQSEQRLDILINNAGVMMCPKWHTDEGFEM 156

Query: 129 QLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQ 188
           Q+GV                K              H+RG+I+  D+NM ++YD   +Y +
Sbjct: 157 QIGVNHLGHFLLTNLLLDMLKKSAPSRIVNVASVAHERGKINFNDINMDKDYDPYQSYYR 216

Query: 189 SKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKK 248
           SKLAN+LF REL  +L  TGV T A+ PG++ T++ RH  +  ++ R  I   F+ F K 
Sbjct: 217 SKLANVLFTRELAIKLRDTGVTTYALHPGVIRTELGRH--VFSNLWRKLIILPFYFFFKN 274

Query: 249 PEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
           P  G QT ++ A+D  LK  +G YY D    E + + +D   A+ LW +S +   L
Sbjct: 275 PWQGAQTTIYCAVDESLKHSSGLYYSDCAPKETAPQGRDDVAARRLWDLSASMVGL 330


>UniRef50_UPI0000584FC7 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 331

 Score =  185 bits (451), Expect = 1e-45
 Identities = 110/303 (36%), Positives = 156/303 (51%), Gaps = 6/303 (1%)

Query: 6   LFNRDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQ 65
           +F +  + G  +    +   +T IITGAN+GIGK  A DFA+R A+V +ACRD+ K ++ 
Sbjct: 28  IFTKLKFRGAAFRSVAKLTGKTAIITGANTGIGKETALDFARREARVILACRDIAKGQKA 87

Query: 66  RRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDG 125
              I   TN   +     DLAS  S+  F   F  +   L +LVNNAGV   P   T+DG
Sbjct: 88  VEHIRRLTNAGELVVMKLDLASLKSVNAFCEEFCNKVGRLDILVNNAGVFHTPYTKTEDG 147

Query: 126 FETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-YDASA 184
           FE Q GV                K              H+RG +    LN  E+ YD + 
Sbjct: 148 FELQFGVNHLGHFLLTNRLLDLLKASAPSRVIIVSSALHKRGLLDFSKLNPEESEYDKAK 207

Query: 185 AYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWP 244
           AY+ SKLAN+LF +EL +RL   GV T  + PG+++T++ R++   K+      +PL W 
Sbjct: 208 AYANSKLANVLFGKELSKRLDDQGVITYTLHPGVINTELARYLGYSKTFWA-ATFPLRWL 266

Query: 245 FMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQ---DFELAQWLWRVSEAW 301
           FMK P  G QT ++ A+  +L+  +G YY + K+ EP  E +   D  +A  LW VSE  
Sbjct: 267 FMKSPWYGAQTTIYCAVADELEAVSGKYYGNCKE-EPYPEVKGTADDAVATKLWEVSERL 325

Query: 302 TKL 304
           T L
Sbjct: 326 TGL 328


>UniRef50_Q4SN30 Cluster: Chromosome 6 SCAF14544, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 6 SCAF14544, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 283

 Score =  182 bits (444), Expect = 8e-45
 Identities = 104/250 (41%), Positives = 134/250 (53%), Gaps = 6/250 (2%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLETNNKYVY 79
           VR D +T ++TG N+GIGK  AKD A RG A+V +ACRD+ K E+   DI+ E     V 
Sbjct: 16  VRLDGKTAVVTGGNTGIGKETAKDLASRGGARVVLACRDMAKGEQAASDIMREVGGAKVV 75

Query: 80  CRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXX 139
            R  DLA T SI +F       E  LH L+NNAGV   P+G+T DG ETQ GV       
Sbjct: 76  ARLLDLADTKSICQFAENIYNTEKTLHYLINNAGVAFCPRGITADGHETQFGVNHLGHFF 135

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                    K              H  GRI   DLN  ++Y    AY+QSKLAN+LF RE
Sbjct: 136 LTYLLLDQLKHSAPSRVINLTSAAHAMGRIQFDDLNGEKSYHPVKAYAQSKLANVLFTRE 195

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
           L RR+   GV+T +VDPG+VDT+ITRH   ++ + RF     F   ++ P  G  T V+ 
Sbjct: 196 LARRIGVLGVSTYSVDPGMVDTEITRH--FIRPLARF--TKTFGFLIRTPAEGAYTTVYC 251

Query: 260 ALDPKLKDCA 269
            + P+   CA
Sbjct: 252 VVTPE-SQCA 260


>UniRef50_A7SMN3 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 332

 Score =  177 bits (431), Expect = 3e-43
 Identities = 113/308 (36%), Positives = 153/308 (49%), Gaps = 11/308 (3%)

Query: 5   FLFNRDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEE 64
           +LF R Y  G     +VR   +T+I+TGANSGIGKA A + A+RGA+V MACRD++  E+
Sbjct: 26  WLFRR-YLVGRRCTNTVRLHGKTVIVTGANSGIGKATALELARRGARVIMACRDLESAEK 84

Query: 65  QRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKD 124
              +I  +     V CR  DL S  S+R+F      EE  L +LVNNAGV +P    T D
Sbjct: 85  AASEIRYKVPKAEVVCRFLDLNSLISVRKFAEDVMREEKRLDILVNNAGVYQPANKKTVD 144

Query: 125 GFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRI-----HKQDL---NM 176
           GFETQ GV                K                R  +      K+D    +M
Sbjct: 145 GFETQFGVNHLGHFLLTNMLLDLLKASAPSRIVVVSSRLGFRANLDFDAFDKEDTDKKSM 204

Query: 177 SENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRF 236
              +     Y +SKLAN LF  EL +R L  GV   A+ PG+V T + R  S M    + 
Sbjct: 205 RGGHVMPVGYGRSKLANFLFTHELSKR-LPQGVTVNALCPGMVWTGLGR-TSKMSWKMKL 262

Query: 237 FIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWR 296
             +PL + F+K+P  G QTV++ A +PKL + +G  + D  + +      D E A+ LW 
Sbjct: 263 LFWPLGFLFLKRPMEGAQTVIYCATEPKLSNVSGKCFTDCHQTDMPANCTDDETAKRLWN 322

Query: 297 VSEAWTKL 304
           VSE  T L
Sbjct: 323 VSEILTGL 330


>UniRef50_Q9HBH5 Cluster: Retinol dehydrogenase 14; n=23;
           Deuterostomia|Rep: Retinol dehydrogenase 14 - Homo
           sapiens (Human)
          Length = 336

 Score =  177 bits (430), Expect = 4e-43
 Identities = 106/292 (36%), Positives = 151/292 (51%), Gaps = 14/292 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQ----RRDI--VLETNNK--- 76
           +T++ITGANSG+G+A A +  + GA+V M CRD  + EE     RR++    E   +   
Sbjct: 44  KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGV 103

Query: 77  ----YVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGV 132
                +  R  DLAS  S+R F      EEP L VL+NNAG+ + P   T+DGFE Q GV
Sbjct: 104 SGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGV 163

Query: 133 XXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLA 192
                           K              ++ G I+  DLN  ++Y+ S  YS+SKLA
Sbjct: 164 NHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRSKLA 223

Query: 193 NLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIG 252
           N+LF REL RRL GT V    + PG+V T++ RH+ +   V   F   + W F K P  G
Sbjct: 224 NILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNL-VSWAFFKTPVEG 282

Query: 253 GQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
            QT ++ A  P+++  +G Y+ D K+ E   +A D  +A+ LW +SE    L
Sbjct: 283 AQTSIYLASSPEVEGVSGRYFGDCKEEELLPKAMDESVARKLWDISEVMVGL 334


>UniRef50_A7RNX1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 282

 Score =  170 bits (414), Expect = 4e-41
 Identities = 105/278 (37%), Positives = 144/278 (51%), Gaps = 8/278 (2%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +T+IITGANSGIG   A+D A R A+V MACRDV K  +   +IV    N  V  +  DL
Sbjct: 2   KTVIITGANSGIGMEVARDLAWRKARVIMACRDVHKGMKAAAEIVQSAGNMDVEVKKLDL 61

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           AS ASIREF      EE  + VL+NNAG +   K  T D  E  L V             
Sbjct: 62  ASFASIREFAKEVNEEESRVDVLINNAGYLGSQK-KTVDKLEYTLQVNYLGPFLLTNLLL 120

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
              K              H++  I   +L   ++Y   AAYS+SKLA +LF ++L  +L 
Sbjct: 121 GKLKTSSPSRIINVSSHQHKKASIDFDNLQGEKSYGRFAAYSRSKLALMLFTKQLANKLA 180

Query: 206 GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWP----FMKKPEIGGQTVVHAAL 261
           G  V   A+ PGLV T++ R++  ++    + I P++W     F K P  G QT +H A+
Sbjct: 181 GYKVTVNALHPGLVCTNLFRNLRFLRI---WAIRPIYWLVQYFFFKTPIQGAQTTIHCAV 237

Query: 262 DPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
            P+L D  G Y+VD ++AE  + A+D  L + LW  SE
Sbjct: 238 APELADVTGKYFVDCQEAECGEVARDEGLGKKLWEKSE 275


>UniRef50_Q6TUD3 Cluster: LRRGT00111; n=3; Euteleostomi|Rep:
           LRRGT00111 - Rattus norvegicus (Rat)
          Length = 407

 Score =  167 bits (406), Expect = 3e-40
 Identities = 93/250 (37%), Positives = 133/250 (53%), Gaps = 5/250 (2%)

Query: 49  GAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVL 108
           GA+V++ACRD++K E    +I   T N  V  R  DLA T SIR F   F  EE +LH+L
Sbjct: 146 GARVYLACRDMQKGELVASEIQATTGNSQVLVRKLDLADTKSIRAFAEGFLAEEKYLHIL 205

Query: 109 VNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGR 168
           +NNAGVM  P   T DGFE   GV                K              H  GR
Sbjct: 206 INNAGVMMCPYSKTADGFEMHFGVNHLGHFLLTHLLLEKLKESGPSRVVNVSSLAHHLGR 265

Query: 169 IHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMS 228
           IH  +L+  + Y    AY  SKLAN+LF +EL RRL G+ V T +V PG V +++ RH +
Sbjct: 266 IHFHNLHGEKFYSGGLAYCHSKLANILFTKELARRLKGSRVTTYSVHPGTVHSELIRHST 325

Query: 229 MMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDF 288
            +K     +++ LF+ F+K P+ G QT ++ A+   ++  +G ++ D + A  S +A + 
Sbjct: 326 ALK-----WLWQLFFFFIKTPQQGAQTSLYCAVTEGIEGLSGSHFSDCQLAWVSSQAGNE 380

Query: 289 ELAQWLWRVS 298
            +A+ LW VS
Sbjct: 381 TIARRLWDVS 390



 Score = 39.1 bits (87), Expect = 0.15
 Identities = 16/30 (53%), Positives = 22/30 (73%)

Query: 20  SVRADNRTIIITGANSGIGKAAAKDFAKRG 49
           +V+   +  I+TGAN+GIGK  AKD A+RG
Sbjct: 79  NVQLSGKVAIVTGANTGIGKETAKDLARRG 108


>UniRef50_UPI00005873A1 Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 335

 Score =  165 bits (402), Expect = 1e-39
 Identities = 97/283 (34%), Positives = 150/283 (53%), Gaps = 5/283 (1%)

Query: 22  RADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCR 81
           R D +T+I+TGAN+GIGK  A+D A+RGA+V +ACRD  +  E  +DI + T N  V   
Sbjct: 55  RLDGKTVIVTGANTGIGKETARDLARRGARVILACRDAVRGREAEKDIRMSTGNDDVIFM 114

Query: 82  PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX 141
             +LAS  SIR F   F   E  L +LVNNAGV+      T++G E   GV         
Sbjct: 115 KLNLASFDSIRHFAQEFNNTEERLDILVNNAGVINDGSLRTEEGHELVFGVNHLGHFLLT 174

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELG 201
                  +              +  G++  + L++++    S  Y++SKLAN+LF R+L 
Sbjct: 175 NILLDKLQKCAPSRVINVSSDAYMFGKLDLERLSVNDGRVKS--YARSKLANVLFTRQLA 232

Query: 202 RRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAAL 261
            ++ GTGV + ++ PG V+T+I R+ +      R     + + F+K  + G QT +H A+
Sbjct: 233 DKMAGTGVVSFSLHPGSVNTEIKRNWA---GWLRALAPLISFFFLKSVKAGAQTSIHCAV 289

Query: 262 DPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
              + D +G+++   +  + S+ AQD +LAQ LW VS   T L
Sbjct: 290 SDDILDQSGEFFKGCQVQKLSRTAQDQDLAQRLWDVSLEMTGL 332


>UniRef50_Q5U3E7 Cluster: Zgc:103654; n=6; Clupeocephala|Rep:
           Zgc:103654 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 296

 Score =  165 bits (402), Expect = 1e-39
 Identities = 101/297 (34%), Positives = 149/297 (50%), Gaps = 12/297 (4%)

Query: 15  PPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETN 74
           P    + R D +T+I+TGAN+GIGKA A D A+RGA+V +ACRD  + +    DI  ET 
Sbjct: 4   PRCTSTARLDGKTVIVTGANTGIGKATAMDLARRGARVILACRDEGRAQAAVTDIQRETG 63

Query: 75  NKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXX 134
           +K V     DLAS  S+R F   F  +E  L +L+NNAG++    G T+DGF    GV  
Sbjct: 64  SKEVLYMHLDLASLKSVRSFAENFLKKESRLDILINNAGLV--IGGKTEDGFGRMFGVNH 121

Query: 135 XXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENY---DASAA----YS 187
                         K              H  G++    +N  ++    D++      YS
Sbjct: 122 LGHFLLTDLLLKRLKECGPSRIVTVSSMAHAWGKMDFNCINAQKDLGKGDSALGLLMLYS 181

Query: 188 QSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMK 247
            SKL N+LF  EL +RL GT V   ++ PG + T+++RH ++  S+   F+ P+F  F K
Sbjct: 182 HSKLCNVLFTHELAKRLKGTNVTCYSLHPGAIKTELSRHSNIWWSL---FMAPIFLLFFK 238

Query: 248 KPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
               G QT +H AL   ++  +G Y+        S +A+D   A+ LW +SE +  L
Sbjct: 239 DVVSGAQTSLHCALQEGIEPLSGRYFSGCAVQNVSAKARDDAAAKKLWEISERFVGL 295


>UniRef50_UPI0000D5685B Cluster: PREDICTED: similar to CG31235-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG31235-PA - Tribolium castaneum
          Length = 345

 Score =  156 bits (379), Expect = 6e-37
 Identities = 94/299 (31%), Positives = 147/299 (49%), Gaps = 2/299 (0%)

Query: 9   RDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRD 68
           R Y  G       R D + +IITG +SGIG   AK+ AK+GA++ +A R+ ++ +     
Sbjct: 31  RAYIGGAHCPSRSRIDGKIVIITGGSSGIGLTTAKELAKKGARIILAVRNAERGKRALEY 90

Query: 69  IVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFET 128
           ++ E        +  DL    SIREF  +   E   + +L+NNAG++  P   T DG E 
Sbjct: 91  LLRECPEAEAIIKLVDLNDFVSIREFANQINLEYERVDILINNAGIIFHPFRKTVDGNEM 150

Query: 129 QLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQ 188
            +                                 H RG+I   DLN  +++    A+SQ
Sbjct: 151 TISTNYFGPFLLTHLLLNLLSKSDNGRVINLSAVAHLRGKIDLDDLNSEKSFVEIEAFSQ 210

Query: 189 SKLANLLFARELGRRLLGTGVATIAVDPGLV-DTDITRHMSMMKS-VTRFFIYPLFWPFM 246
           SKLA  +F + +   L  T +   AV+PGLV  T   R+  +  S VT+F ++P  W FM
Sbjct: 211 SKLALTMFTKHMASLLKHTNITFNAVNPGLVRGTRHLRNSRVTTSFVTKFSVWPWMWLFM 270

Query: 247 KKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLD 305
           K P+ G QTV++ A+DP LK+ +G Y+ + +  +PS    D EL++ L++ +    K+D
Sbjct: 271 KTPKQGSQTVIYVAIDPFLKNVSGCYFSNCEIQKPSDLVNDVELSEKLYKKTCEIVKID 329


>UniRef50_A5UPA5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Roseiflexus sp. RS-1|Rep: Short-chain
           dehydrogenase/reductase SDR - Roseiflexus sp. RS-1
          Length = 288

 Score =  155 bits (377), Expect = 1e-36
 Identities = 92/274 (33%), Positives = 137/274 (50%), Gaps = 5/274 (1%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R  ++TGAN+GIGKA A   A+ GA V M CR+  + E  + ++    +      R  DL
Sbjct: 7   RVCVVTGANTGIGKATALGLARMGATVVMICRNRARGEAAQTEVQRVASAPVDLFR-ADL 65

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           +S A +R+     +    H+HVL++NAG+  P + ++ DG E  L V             
Sbjct: 66  SSQAEVRQVADDIRARYAHIHVLIHNAGLQLPQRTLSVDGIEMTLAVNHGAPFLLTHCLL 125

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
              K              H+ G I   DL++   Y    AY +SKL N+LF REL RRL 
Sbjct: 126 DALKAGAPSRIVVVSSLVHRWGSIDFDDLHLERGYTMDRAYFRSKLCNVLFTRELARRLS 185

Query: 206 GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWP-FMKKPEIGGQTVVHAALDPK 264
           G+GV   +++PGLV TD  R   +   V  +F++ ++   F + PE G QT V+ A  P+
Sbjct: 186 GSGVTANSLEPGLVKTDFAR---VYTGVQGWFVHNVWMRLFAQTPEQGAQTSVYLATSPE 242

Query: 265 LKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           +    G ++   +  EPS  A+D  LA+ LW VS
Sbjct: 243 VAGVTGAHFAKCRPIEPSTLARDDALARRLWDVS 276


>UniRef50_UPI000155BF31 Cluster: PREDICTED: similar to double
           substrate-specificity short chain
           dehydrogenase/reductase 2, partial; n=1; Ornithorhynchus
           anatinus|Rep: PREDICTED: similar to double
           substrate-specificity short chain
           dehydrogenase/reductase 2, partial - Ornithorhynchus
           anatinus
          Length = 408

 Score =  153 bits (370), Expect = 8e-36
 Identities = 83/185 (44%), Positives = 99/185 (53%)

Query: 20  SVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVY 79
           +VR   +  +ITGAN+GIGK  A+D A+RGA+V +ACRDV K E    +I  ET N+ V 
Sbjct: 3   TVRLHGKVAVITGANTGIGKETARDLARRGARVIIACRDVLKGESAAGEIRAETGNRQVL 62

Query: 80  CRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXX 139
            R  DLA T SIR F  RF  EE  LH+L+NNAGVM  P   T DGFE  LGV       
Sbjct: 63  VRKLDLADTKSIRAFADRFLAEEKQLHILINNAGVMMCPYSKTADGFEMHLGVNHLGHFL 122

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                    K              H  G+I   DL   + Y+   AY  SKLAN+LF RE
Sbjct: 123 LTHLLLGRLKESAPARVVNVSSLAHIIGKIRFHDLQGEKYYNHGLAYCHSKLANILFTRE 182

Query: 200 LGRRL 204
           L RRL
Sbjct: 183 LARRL 187


>UniRef50_Q9VE80 Cluster: CG7675-PB, isoform B; n=9;
           Endopterygota|Rep: CG7675-PB, isoform B - Drosophila
           melanogaster (Fruit fly)
          Length = 336

 Score =  152 bits (368), Expect = 1e-35
 Identities = 91/284 (32%), Positives = 140/284 (49%), Gaps = 4/284 (1%)

Query: 22  RADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCR 81
           + + +T+IITGANSGIGK  AKD A RGA++ MACR+++     + +IV ET N  +  +
Sbjct: 49  KMEGKTVIITGANSGIGKETAKDLAGRGARIIMACRNLETANAVKDEIVKETKNNKILVK 108

Query: 82  PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVT-KDGFETQLGVXXXXXXXX 140
             DL S  S+REF A     EP + VL++NAG+    +G T +DG E  +          
Sbjct: 109 KLDLGSQKSVREFAADIVKTEPKIDVLIHNAGMALAFRGQTSEDGVELTMATNHYGPFLL 168

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAREL 200
                   K              ++   ++   LN    + A+  Y  SK AN+ FAREL
Sbjct: 169 THLLIDVLKKSAPARIVIVASELYRLSSVNLAKLNPIGTFPAAYLYYVSKFANIYFAREL 228

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAA 260
            +RL GT V    + PG++D+ I R++    ++    I      F K  + G QT ++ A
Sbjct: 229 AKRLEGTKVTVNFLHPGMIDSGIWRNVPFPLNLPMMAITK---GFFKTTKAGAQTTIYLA 285

Query: 261 LDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
              ++ + +G Y++D K+A  +  A D E    +W  S    KL
Sbjct: 286 TSNEVANVSGKYFMDCKEATLNAAALDEEKGLKIWEESVKIVKL 329


>UniRef50_Q66IF0 Cluster: Zgc:101565; n=2; Clupeocephala|Rep:
           Zgc:101565 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 318

 Score =  151 bits (367), Expect = 2e-35
 Identities = 97/287 (33%), Positives = 140/287 (48%), Gaps = 12/287 (4%)

Query: 20  SVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVY 79
           S     +T IITG N+GIGKA A D A RG +V +ACR+ KK E    DI   T +  V 
Sbjct: 31  SADVTGKTAIITGGNTGIGKATALDLAGRGMRVILACRNQKKAEAAINDIKKATGSDEVL 90

Query: 80  CRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXX 139
               DL S  S+R F   F   E  L +L+NNAG++    G T+DGF  + GV       
Sbjct: 91  FMELDLGSLKSVRAFAETFLKSESRLDLLINNAGLV--ADGRTEDGFGIEFGVNHLGHFL 148

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIH------KQDLNMSE-NYDASAAYSQSKLA 192
                    K              ++ GRI        +DL     ++    AY  SKL 
Sbjct: 149 LTCLLLDRLKESPAARVITLSSMAYRWGRIDFDSLITTKDLGSGRYSWQFFQAYCNSKLC 208

Query: 193 NLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIG 252
           N+LF  EL +RL GT V   +V PG+V T+++R++S+ + V   FI P+       P+ G
Sbjct: 209 NVLFTHELAKRLKGTSVTCYSVHPGVVKTELSRNVSLWQKV---FIEPVARLLFLDPKTG 265

Query: 253 GQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
            QT +H A+   ++  +G Y+      E   +A+D  +A+ LW++SE
Sbjct: 266 AQTTLHCAVQEGIEHFSGRYFSCCAVEEVGAKAKDDAVARKLWQISE 312


>UniRef50_Q4TAJ0 Cluster: Chromosome undetermined SCAF7304, whole
           genome shotgun sequence; n=1; Tetraodon
           nigroviridis|Rep: Chromosome undetermined SCAF7304,
           whole genome shotgun sequence - Tetraodon nigroviridis
           (Green puffer)
          Length = 352

 Score =  150 bits (364), Expect = 4e-35
 Identities = 81/197 (41%), Positives = 107/197 (54%), Gaps = 1/197 (0%)

Query: 9   RDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRD 68
           R + +G     SVR D +T++ITGAN+GIGK  +++ A+RGA+V +ACRD+ + E    +
Sbjct: 3   RRWIAGGVCRSSVRLDGKTVLITGANTGIGKETSRELARRGARVVLACRDLTRAERSADE 62

Query: 69  IVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFET 128
           I   T N  V  R  DL+S  SIR+F   F   E  L VL+NNAGVM  P+ +T+DGFET
Sbjct: 63  IRRSTGNGNVVVRHLDLSSLCSIRQFTREFLDSEDRLDVLINNAGVMMCPRWLTEDGFET 122

Query: 129 QLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS-ENYDASAAYS 187
           Q GV                K              H+ G +H  DL  S   Y    +Y 
Sbjct: 123 QFGVNHLGHFLLTNLLLPKLKSSAPSRVVTVSSIAHRGGHVHFDDLFFSRRTYSPLESYR 182

Query: 188 QSKLANLLFARELGRRL 204
           QSKLAN+LF+ EL RRL
Sbjct: 183 QSKLANVLFSAELARRL 199


>UniRef50_UPI0000D569DF Cluster: PREDICTED: similar to CG30495-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG30495-PA - Tribolium castaneum
          Length = 326

 Score =  149 bits (362), Expect = 7e-35
 Identities = 99/293 (33%), Positives = 143/293 (48%), Gaps = 18/293 (6%)

Query: 11  YYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIV 70
           Y++G     + R D   ++ITG NSGIGKA A + A+RGA + +ACRDV+K    ++DI+
Sbjct: 21  YFAGGVCKCTARLDGLVVVITGGNSGIGKALAVELAQRGATLVLACRDVEKGINAKKDIL 80

Query: 71  LETNNKYV--YCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFET 128
           L  NNK V  + +  DLAS +SI +F    K E   ++ LVNNAG+   P  VT+DG+E 
Sbjct: 81  LSLNNKNVKIFVKRLDLASVSSILKFSESLKCEFSEIYALVNNAGIFYHPHTVTEDGYEI 140

Query: 129 QLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLN-----MSENYDAS 183
                               K              H+   ++  DLN      +E     
Sbjct: 141 TFQTNYLGHFILTHNLLTLLKKADHSRIVNVTSEAHRLVNVY--DLNAITKSQTEFRSHL 198

Query: 184 AAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFW 243
            AY  +KLA +LF R L ++L  T +   A +PG V+T + R+   + +    F+Y L W
Sbjct: 199 VAYGVTKLALILFTRYLFKKLSNTNIIVNAANPGNVETSLFRYFPFLSNK---FLYGLQW 255

Query: 244 PF----MKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQ 292
           P     +K P  G QT++H  L        G YY D K + PS  A D +LA+
Sbjct: 256 PIRQIVVKSPRQGAQTILHCLLTS--NRTTGQYYSDCKLSLPSPLALDDKLAK 306


>UniRef50_Q9U1Y6 Cluster: Putative uncharacterized protein dhs-24;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein dhs-24 - Caenorhabditis elegans
          Length = 384

 Score =  147 bits (357), Expect = 3e-34
 Identities = 99/314 (31%), Positives = 147/314 (46%), Gaps = 13/314 (4%)

Query: 13  SGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLE 72
           SG  YD       +T I+TGA SGIG+A A++ AKR A+V MACR+ +KC + RRDIVL 
Sbjct: 36  SGTKYDLHEDLAGKTYIVTGATSGIGQATAEELAKRNARVIMACRNREKCVQVRRDIVLN 95

Query: 73  TNNKYVYCRPCDLASTASIREFVARF---KGEEPHLHVLVNNAGVMEPPKGVTKDGFETQ 129
           T NK VYCR CDL    SIR FV +    K E   +  +V+NA +M+  + V KDG E  
Sbjct: 96  TRNKQVYCRQCDLEDFDSIRTFVQKLSKGKFELDRIDGIVHNAAMMQSERAVNKDGIEKT 155

Query: 130 LGV--XXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN----YDAS 183
           +                    +               ++  ++  D N SEN    +D  
Sbjct: 156 IATNHLGSFLLTGLLLDKLLAQPNPVRIVFLNSNIIDRKCDLNLADFN-SENAGKKFDGY 214

Query: 184 AAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPL-- 241
             Y  SKLA+ LF +EL  RL  T +  +  DPG   ++++  M         ++  +  
Sbjct: 215 EIYKHSKLASALFTKELSERLSDTNIHVLMADPGRTKSNLSAQMDGQTFFLSRWLLKIVS 274

Query: 242 FWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEA-QDFELAQWLWRVSEA 300
           F    ++ E   + V+ A  DP   D  G +    +  +P  +   D    + LW VS  
Sbjct: 275 FGMGERRTEKAVRPVLFALCDPDTSDENGLFIDRERHQQPWNDVIMDAAKREKLWNVSVT 334

Query: 301 WTKLDEHKQAIAKD 314
           WT+L EH + + ++
Sbjct: 335 WTRLGEHLKKMKEE 348


>UniRef50_Q8N5I4 Cluster: Dehydrogenase/reductase SDR family member
           on chromosome X precursor; n=10; Euarchontoglires|Rep:
           Dehydrogenase/reductase SDR family member on chromosome
           X precursor - Homo sapiens (Human)
          Length = 330

 Score =  147 bits (356), Expect = 4e-34
 Identities = 97/280 (34%), Positives = 134/280 (47%), Gaps = 9/280 (3%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           +R  I+TG   GIG + AK  A+ G  V +A  +  K ++    I  ET N  V    CD
Sbjct: 43  DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           LAS  SIR+FV +FK ++  LHVL+NNAGVM  P+  T+DGFE   G+            
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLL 162

Query: 145 XXXXKXX----XXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAREL 200
               K                  H    ++  DL  S  Y   AAY+QSKLA +LF   L
Sbjct: 163 LDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHL 222

Query: 201 GRRLL--GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVH 258
            R L   G+ V    VDPG+V+TD+ +H+      TR     L W   K P+ G  T ++
Sbjct: 223 QRLLAAEGSHVTANVVDPGVVNTDLYKHVFW---ATRLAKKLLGWLLFKTPDEGAWTSIY 279

Query: 259 AALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           AA+ P+L+   G Y  + K+ +      + +L Q LW  S
Sbjct: 280 AAVTPELEGVGGRYLYNEKETKSLHVTYNQKLQQQLWSKS 319


>UniRef50_UPI0000D57162 Cluster: PREDICTED: similar to short-chain
           dehydrogenase/reductase 1; n=8; Tribolium castaneum|Rep:
           PREDICTED: similar to short-chain
           dehydrogenase/reductase 1 - Tribolium castaneum
          Length = 331

 Score =  145 bits (352), Expect = 1e-33
 Identities = 97/293 (33%), Positives = 143/293 (48%), Gaps = 13/293 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +T IITG+N+GIG   A DFAKRGA+V +ACR+  K EE R  IV ET N  V  +  DL
Sbjct: 37  KTTIITGSNTGIGYETALDFAKRGARVILACRNAAKAEEARSKIVSETGNANVVVKLLDL 96

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           +S  S+R F       E  L +LVNNAGV+      +KDG    + +             
Sbjct: 97  SSFDSVRAFAKEINETENRLDILVNNAGVIGIGDDTSKDGLSLVIQINHFSGFLLTNLLI 156

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
              K               +  +    D  + ++      Y  SKL N+LF +EL R+L 
Sbjct: 157 SLLKKSAPSRVVNVSSMAAEGAKNLDLD-KIGQHVSVMEDYCNSKLCNVLFTQELARKLD 215

Query: 206 GTGVATIAVDPGLVDTDITRHMS-MMK---SVTR--FFIYPLFW------PFMKKPEIGG 253
           GTGV T ++ PG+V+T+I  + S ++K   SV R        FW         +  E G 
Sbjct: 216 GTGVTTYSLHPGVVETEIVNNTSGILKIGFSVLRKLHSKVKFFWLRGGLVGLFQTVEEGA 275

Query: 254 QTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLDE 306
           QT +  ++   +++  G+++ D K+ EP + A++  LA+ LW  SE   +L E
Sbjct: 276 QTSIFCSVAKGIENHNGEHFSDCKRVEPYKTARNPGLAKKLWEKSEQIVRLQE 328


>UniRef50_Q6UX07 Cluster: Dehydrogenase/reductase SDR family member
           13; n=33; Euteleostomi|Rep: Dehydrogenase/reductase SDR
           family member 13 - Homo sapiens (Human)
          Length = 377

 Score =  145 bits (352), Expect = 1e-33
 Identities = 95/288 (32%), Positives = 136/288 (47%), Gaps = 8/288 (2%)

Query: 15  PPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETN 74
           PP         RT ++TGANSGIGK  A + A+RGA+V +ACR  ++ E    D+  E+ 
Sbjct: 26  PPCGGMGNLRGRTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESG 85

Query: 75  NKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXX 134
           N  V     DLAS AS+R F   F   EP L +L++NAG+     G T++ F   L V  
Sbjct: 86  NNEVIFMALDLASLASVRAFATAFLSSEPRLDILIHNAGISS--CGRTREAFNLLLRVNH 143

Query: 135 XXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRI--HKQDLNMSENYDASAAYSQSKLA 192
                         K              H RGR+   + D  +        AY+ +KLA
Sbjct: 144 IGPFLLTHLLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLA 203

Query: 193 NLLFARELGRRLLGTGVATIAVDPGLVDTDI-TRHMSMMKSVTRFFIYPLFWPFMKKPEI 251
           N+LFAREL  +L  TGV   A  PG V++++  RH   +    R  + PL W  ++ P  
Sbjct: 204 NVLFARELANQLEATGVTCYAAHPGPVNSELFLRH---VPGWLRPLLRPLAWLVLRAPRG 260

Query: 252 GGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
           G QT ++ AL   ++  +G Y+ +    E    A+D   A  LW  S+
Sbjct: 261 GAQTPLYCALQEGIEPLSGRYFANCHVEEVPPAARDDRAAHRLWEASK 308


>UniRef50_Q8EQH7 Cluster: Alcohol dehydrogenase; n=1; Oceanobacillus
           iheyensis|Rep: Alcohol dehydrogenase - Oceanobacillus
           iheyensis
          Length = 290

 Score =  145 bits (351), Expect = 2e-33
 Identities = 88/281 (31%), Positives = 136/281 (48%), Gaps = 12/281 (4%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           N+TII+TGAN+G+G A   + AK+G  V MACRD K+  E +   + E+N+  +    CD
Sbjct: 3   NKTIIVTGANTGMGLATTIELAKKGIHVIMACRDTKRGNEAKEKAMEESNSTNISLYQCD 62

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           L S  SI +F  + K +   +  L+NNAGV+      T+DGFE+  GV            
Sbjct: 63  LGSMESISKFADQIKEDFDKIDGLINNAGVVSLKHTKTEDGFESMTGVNHLGHFLLTHLL 122

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNM-SENYDASAAYSQSKLANLLFARELGRR 203
               K              ++ G +   D++  + +++    Y QSKL N+LF  EL + 
Sbjct: 123 LDVLKKSEQARIINVASGAYKAGTLDYNDMHFNNRSFNVIKGYGQSKLCNILFTLELNKH 182

Query: 204 LLGTGVATIAVDPGLVDTD--ITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAAL 261
           L GT V+T A+ PG V T   + R     + V     + L  PF    E G +T ++ A 
Sbjct: 183 LEGTNVSTFALHPGAVSTSLGVDRQTGFGEKV-----HLLLRPFFLTSEEGAETAIYLAT 237

Query: 262 DPKLKDCAGDYYVDMKKAEP---SQEAQDFELAQWLWRVSE 299
           +PK+   +G Y+   KK +P   ++  +D     W W + E
Sbjct: 238 EPKIDHLSGRYFY-KKKLQPTKYNKVNEDEAKKLWDWSIKE 277


>UniRef50_Q7D9T6 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=11;
           Actinomycetales|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family - Mycobacterium
           tuberculosis
          Length = 338

 Score =  144 bits (349), Expect = 3e-33
 Identities = 99/287 (34%), Positives = 136/287 (47%), Gaps = 13/287 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R +++TGAN+GIG   A  FA RGA V +A R+++K    R  I+      +V  +  DL
Sbjct: 49  RVVVVTGANTGIGYHTAAVFADRGAHVVLAVRNLEKGNAARARIMAARPGAHVTLQQLDL 108

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
            S  S+R      +   P + VL+NNAGVM  PK VTKDGFE Q G              
Sbjct: 109 CSLDSVRAAADALRTAYPRIDVLINNAGVMWTPKQVTKDGFELQFGTNHLGHFALTGLVL 168

Query: 146 XXXKXXXXXXXXXXXXXXHQ-RGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
                             H+    IH  DL     Y+  AAY Q+KLANLLF  EL RRL
Sbjct: 169 DHMLPVPGSRVVTVSSQGHRIHAAIHFDDLQWERRYNRVAAYGQAKLANLLFTYELQRRL 228

Query: 205 LGTGVATIAV--DPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
              G +TIAV   PG  +T++TR++  +       + PL +   + PE+G    + AA D
Sbjct: 229 GEAGKSTIAVAAHPGGSNTELTRNLPRLIRPVATVLGPLLF---QSPEMGALPTLRAATD 285

Query: 263 PKLK-------DCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWT 302
           P  +       D  G+     K  + S ++ D +L + LW VSE  T
Sbjct: 286 PTTQGGQYYGPDGFGEQRGHPKVVQSSAQSHDKDLQRRLWTVSEELT 332


>UniRef50_Q3E046 Cluster: NAD-dependent
           epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR; n=3; Bacteria|Rep:
           NAD-dependent epimerase/dehydratase:Short-chain
           dehydrogenase/reductase SDR - Chloroflexus aurantiacus
           J-10-fl
          Length = 292

 Score =  144 bits (348), Expect = 3e-33
 Identities = 92/275 (33%), Positives = 126/275 (45%), Gaps = 5/275 (1%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNK-YVYCRPCD 84
           +T+I+TGANSGIG   A++ A  GA+V M CR   K E  R+ I+ E            D
Sbjct: 13  KTVIVTGANSGIGYVTARELAAMGARVIMVCRSQSKGEAARQRIMQEAKGAPEPELVLAD 72

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
            AS AS+R          P + VLVNNAG+       + DG+E    V            
Sbjct: 73  FASLASVRRAAGDILERCPRIDVLVNNAGLFVSEPLASADGYEMTFAVNHLAPFLLTNLL 132

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
                              H  GRI    +   +  + + AYS SKL N+LF  EL RRL
Sbjct: 133 LERIIASAPARIINVSSFAHVAGRIAIPQIASPQRPNIAQAYSDSKLCNILFTNELARRL 192

Query: 205 LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPK 264
            G+GV   ++ PG V T+        + +  FF + L  PFM  PE G  T ++ A  P+
Sbjct: 193 QGSGVTANSLHPGAVATNFAADS---RGLFAFF-FRLARPFMLSPEHGAATSIYLASSPE 248

Query: 265 LKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
           + + +G Y+V  K  +PS  AQ   LA+ LW  SE
Sbjct: 249 VAEISGQYFVRKKPVKPSAAAQGAALAKRLWEFSE 283


>UniRef50_A7RNF1 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 296

 Score =  143 bits (347), Expect = 5e-33
 Identities = 94/287 (32%), Positives = 134/287 (46%), Gaps = 13/287 (4%)

Query: 22  RADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCR 81
           RA  +  I+TG N GIG   A+   + G  V M CR  K  E   + +  E  +  V   
Sbjct: 12  RAAGKVAIVTGGNCGIGYETARGLIRSGMTVIMGCRSEKAAESAIQHLKDEQPDARVRYI 71

Query: 82  PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX 141
             DL+  +S+REFV  F   E  L+VLVNNAGVM  P  +TKDGFE Q+G+         
Sbjct: 72  HLDLSDLSSVREFVKSFHQSENQLNVLVNNAGVMLTPYALTKDGFEQQIGICHFGHFLLT 131

Query: 142 XXXXXXXKXXXX----XXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFA 197
                  K                  H  G I+ +DL   ++Y    AY+Q+K+AN+LF 
Sbjct: 132 MLLLDTLKKSGTKDCHSRIVTVSSTAHSSGSINFEDLQSKKSYSRFGAYAQAKVANVLFT 191

Query: 198 RELGRRLL--GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQT 255
             L RRL    T V   A+ PG+V+T++ RH+  +         P+   F   PE G  T
Sbjct: 192 YALQRRLSIDSTHVTANALHPGVVNTELFRHLPWIARA------PM-GLFFLTPEQGAAT 244

Query: 256 VVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWT 302
            ++A L P L+   G Y  + +    S  + + ++ + LWRVS   T
Sbjct: 245 SLYACLSPDLEGVGGKYLANCEVQSSSAYSYNEDIQERLWRVSRKLT 291


>UniRef50_A6W5Z4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR - Kineococcus radiotolerans
           SRS30216
          Length = 319

 Score =  142 bits (343), Expect = 1e-32
 Identities = 99/304 (32%), Positives = 140/304 (46%), Gaps = 18/304 (5%)

Query: 18  DRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNK- 76
           D   R + RT+++TGANSG+G   A +FA+RGA V +ACR+ ++      ++     +  
Sbjct: 12  DAMGRQEGRTVLVTGANSGLGLQVATEFARRGADVLLACRNAERGRAAVAELTAAVRDSG 71

Query: 77  ---YVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVX 133
               V   P D+A  AS+R            + VLVNNAGVM PP G T DGFETQ+G  
Sbjct: 72  VEPTVEVIPLDVADLASVRRAAGDVLHRRSGIDVLVNNAGVMAPPFGRTVDGFETQVGTN 131

Query: 134 XXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLAN 193
                                         H+ GR+++Q+     +Y    AY QSKL+N
Sbjct: 132 HLGHFAFTGLLLPALLTGGGARVVSVASVAHKFGRLNRQNYQSERSYQKWLAYGQSKLSN 191

Query: 194 LLFARELGRR--LLGTGVATIAVDPGLVDTDITRHMSMMKS-VTRFFIYPLFWPFMKKPE 250
           LLFA EL RR   +G G+ + A  PGL DT++ ++  +    V       L     + P 
Sbjct: 192 LLFAFELQRRAAAVGAGIVSTAAHPGLSDTNLWKNTPLAPGRVGAPLGTALSRAVGQPPA 251

Query: 251 IGGQTVVHAALDPKLKDCAGDYYVDMKKAE----PSQ-----EAQDFELAQWLWRVSEAW 301
            G   ++ AA DP +    G+Y+    + E    P Q      A D   A WLW  S  W
Sbjct: 252 QGAWPLLRAATDPAV--VGGEYFGPGGRKEWRGFPVQVQANAAAYDTADAAWLWARSVEW 309

Query: 302 TKLD 305
           T +D
Sbjct: 310 TGVD 313


>UniRef50_Q2S6L7 Cluster: Retinol dehydrogenase 11; n=1;
           Salinibacter ruber DSM 13855|Rep: Retinol dehydrogenase
           11 - Salinibacter ruber (strain DSM 13855)
          Length = 297

 Score =  141 bits (341), Expect = 2e-32
 Identities = 92/288 (31%), Positives = 130/288 (45%), Gaps = 15/288 (5%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKY------VYCRP 82
           ++TGANSGIGKA A + A+ GA+V M CRD  +  E + ++  E    +      +  R 
Sbjct: 7   VVTGANSGIGKATAAELARLGARVVMVCRDEGRGREAQAELRAEARTAHPSRADTIDLRI 66

Query: 83  CDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX 142
            DL+    +       + +   L VLVNNAGV    +  T DG E    V          
Sbjct: 67  ADLSVQEEVYHLGETLRADYDRLDVLVNNAGVFLESREETVDGVEATFAVNHLAPFLLTH 126

Query: 143 XXXXXXKXXXXXXXXXX----XXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAR 198
                 +                  H+   +   DLN    Y+   AY+QSKLAN+LF  
Sbjct: 127 LVLPRLRETAGRAGEARIVTLSSEAHRGVSMDFDDLNAETGYNPLQAYAQSKLANILFTH 186

Query: 199 ELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVH 258
           EL RRL   GV    V PG+V+T+I R    +  + R F     W + K+PE G + VV+
Sbjct: 187 ELSRRLQDEGVVANVVHPGIVNTNIWRGSGWISRIARLF----SWLY-KRPEEGARNVVY 241

Query: 259 AALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLDE 306
            A  P ++   G Y+ + +   PS EA D +    LWR+S   T L E
Sbjct: 242 LAASPDVEGVTGQYFKETEVVNPSPEAYDEKAEARLWRISREMTGLAE 289


>UniRef50_A7SUS7 Cluster: Predicted protein; n=1; Nematostella
           vectensis|Rep: Predicted protein - Nematostella
           vectensis
          Length = 428

 Score =  141 bits (341), Expect = 2e-32
 Identities = 99/297 (33%), Positives = 140/297 (47%), Gaps = 15/297 (5%)

Query: 13  SGPPYD--RSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIV 70
           S   YD  +    D R +++TGA+SGIG A A   A  GA V MACRD++K  +    I 
Sbjct: 120 SSTTYDVLKDENLDGRVVMVTGASSGIGLATASALAAHGAHVVMACRDMEKAHKAELHIK 179

Query: 71  LETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQL 130
               +  +     DLAS ASI +FV +FK +   LHVLV NAGV+  P   T D  E   
Sbjct: 180 KTNKDCKLEVMFVDLASFASIHDFVDKFKKKSMPLHVLVCNAGVLGGPWRCTGDNIEYTF 239

Query: 131 GVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQ------RGRIHKQDLNMS-ENYDAS 183
            V                               H+        ++H   + +S + Y + 
Sbjct: 240 AVNYLGHFLLIKLLQDVLCSSSPARIVMLSSESHRFQDLNYSDKLHISTVPLSRDKYHSI 299

Query: 184 AAYSQSKLANLLFARELGRRLLGTGVATIAVDPG-LVDTDITRHMSMMKSVTRFFIYPLF 242
            AY+QSKL +++ + EL RRL   GV   AV PG L+ T +       KS   + I+ + 
Sbjct: 300 LAYNQSKLCSIMLSMELNRRLSSEGVTCNAVHPGNLIYTSL-----YGKSWCYWLIFRIA 354

Query: 243 WPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
             F K PE    TVV+ A+ P+L    G Y+++ +  EPS EA D + A+ LW +SE
Sbjct: 355 RLFAKTPEQAASTVVYCAVSPELNGVGGQYFINCRPCEPSVEAADPDKARALWTLSE 411


>UniRef50_Q5V0G9 Cluster: Oxidoreductase short-chain
           dehydrogenase/reductase family; n=5;
           Halobacteriaceae|Rep: Oxidoreductase short-chain
           dehydrogenase/reductase family - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 313

 Score =  141 bits (341), Expect = 2e-32
 Identities = 103/297 (34%), Positives = 141/297 (47%), Gaps = 19/297 (6%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           +RT+++TGANSG+G   +K FA+RGA V MACR V++ E    +I     N  +  R CD
Sbjct: 14  DRTVVVTGANSGLGLEGSKAFARRGATVVMACRSVERGESAAAEIREAVPNATLDVRECD 73

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGV-XXXXXXXXXXX 143
           LA  +++  F    + +   + +L NNAGVM  P+  T DGFETQ GV            
Sbjct: 74  LADLSNVASFADGLRADYDAVDILCNNAGVMAIPRSETADGFETQFGVNHLGHFALTGHL 133

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRR 203
                               H+ G I   DL    +Y   +AY QSKLANLLFA EL RR
Sbjct: 134 LDLLGAADGESRIVTQSSGAHEMGEIDFDDLQRERSYGKWSAYGQSKLANLLFAYELQRR 193

Query: 204 LLGTG---VATIAVDPGLVDTDIT-RHMSMMKSVTRFFIYPLF-WPFMKKPEIGGQTVVH 258
           L   G   V ++A  PG  DTD+  R    M S  R     +    F +  E G   +++
Sbjct: 194 LGNHGWDDVLSVACHPGYADTDLQFRGPREMGSTLRTAAMGVANAVFAQSAEQGALPMLY 253

Query: 259 AALDPKLKDCAGDYYV------DMKKAEPSQE----AQDFELAQWLWRVSEAWTKLD 305
           AA     +D  G  YV      DM+ +   Q+    +QD E A+ LW VS   T ++
Sbjct: 254 AA---TAEDVIGGEYVGPGGLFDMRGSPEFQQSNDASQDEETAEQLWAVSTDLTGVE 307


>UniRef50_A1UAG7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=24; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Mycobacterium sp. (strain KMS)
          Length = 306

 Score =  140 bits (339), Expect = 4e-32
 Identities = 100/290 (34%), Positives = 136/290 (46%), Gaps = 16/290 (5%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + R  +ITGAN+GIG  AA   A +GA V +A R+  K       I     +  V  R  
Sbjct: 16  EGRVAVITGANTGIGYEAAAVLAAKGAHVVLAVRNTDKGGAAAERIRSALPHADVTVREL 75

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DL S  SIRE     + + P + +L+NNAGVM   KG TKDGFE QLG            
Sbjct: 76  DLTSLDSIREAADGLRADYPRIDLLINNAGVMMTEKGATKDGFELQLGTNHLGHFALTGQ 135

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRR 203
                               H+ GR++  DL    +Y+   AY QSKLANLLF  EL RR
Sbjct: 136 LLDNLLPVEGSRVVTVSSNAHRWGRVNFDDLQSERSYNRVTAYGQSKLANLLFTYELNRR 195

Query: 204 LLGTGVATIAV--DPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAAL 261
           L   G  TIAV   PG   T++TR+   +  V R  +  ++    + PE+G    + AA 
Sbjct: 196 LSAKGAPTIAVAAHPGTSSTELTRN---LWPVARRPVELVWGLVAQTPEMGALPTLRAAT 252

Query: 262 DPKLKDCAGDYY----VDMKKAEP---SQEAQDFELA--QWLWRVSEAWT 302
           DP ++   G YY    +  ++  P      A+ ++ A  + LW VSE  T
Sbjct: 253 DPDVR--GGQYYGPDGIGEQRGHPKLVQSNARSYDEAAQRRLWSVSEELT 300


>UniRef50_A7DHU1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Methylobacterium extorquens PA1|Rep: Short-chain
           dehydrogenase/reductase SDR - Methylobacterium
           extorquens PA1
          Length = 281

 Score =  139 bits (336), Expect = 1e-31
 Identities = 88/286 (30%), Positives = 131/286 (45%), Gaps = 7/286 (2%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKY-VY 79
           +R D RT ++TGA+SGIG   A   A+ GA+V +  RD ++ E     +   T     V+
Sbjct: 1   MRLDGRTALVTGASSGIGAETALGLARLGARVGLVGRDRERTERAAAHLRRVTGGAADVF 60

Query: 80  CRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXX 139
               DL+S A IR      +   P L +LVNNAG +   + VT DG E    +       
Sbjct: 61  L--ADLSSQAEIRRLAGEVRARYPALDLLVNNAGAIFSERHVTADGIERTWALDHLTYVL 118

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                    +              H RGRI   DL     Y A  AY+Q+KL N+LF   
Sbjct: 119 LTHELRRPLEAAPRARIVNLASAAHTRGRIDFDDLGGERRYTAMKAYAQAKLGNVLFTYA 178

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
           L RRL G+G+   AV PG+V +D  ++          F + L  PF+   E G +T +H 
Sbjct: 179 LARRLAGSGITVNAVHPGVVASDFAKNTRGGLG----FAWSLIRPFLISTEAGARTSLHV 234

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLD 305
           A  P+L   +G Y+   ++   S  ++D  L + +W +S   T ++
Sbjct: 235 AAAPELDGVSGRYFAKSRETASSTRSRDEALQERVWTLSRRQTGIE 280


>UniRef50_Q66KN7 Cluster: MGC85576 protein; n=13; Euteleostomi|Rep:
           MGC85576 protein - Xenopus laevis (African clawed frog)
          Length = 327

 Score =  138 bits (335), Expect = 1e-31
 Identities = 93/281 (33%), Positives = 134/281 (47%), Gaps = 9/281 (3%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + +  I+TG   GIG + AK  ++ G  V +A  +  +  E    I  +T N+ V    C
Sbjct: 40  NGKVAIVTGGAKGIGCSTAKQLSRLGMHVIIAGNNEAEGNEAVTRIQQDTQNEKVEFLYC 99

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DLAS  SIR+FV  F  +   LHVLVNNAGVM  P+  T DGFE   G+           
Sbjct: 100 DLASMKSIRQFVQNFTAKNLCLHVLVNNAGVMLVPERKTADGFEEHFGLNYLGHFLLTNL 159

Query: 144 XXXXXKXXXX----XXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                K                  H  G ++  DLN S  Y    AY+QSKLA ++F   
Sbjct: 160 LLKTMKKSGTENLNARIITVSSATHYVGELNFDDLNSSYCYSPHGAYAQSKLALVMFTYC 219

Query: 200 LGRRLLGTG--VATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVV 257
           L R+L   G  V   AVDPG+V+TD+ R++     + ++      W F K P+ G  T V
Sbjct: 220 LQRQLSEDGCYVTANAVDPGVVNTDLYRNVCWPGRLVKWL---TAWLFFKTPDEGAATSV 276

Query: 258 HAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           +A++ P+L+   G Y    +K + +  + + EL + LW  S
Sbjct: 277 YASVAPELEGIGGCYLYSGQKTKSADVSYNEELQRKLWNES 317


>UniRef50_UPI00006CAF29 Cluster: oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=3; Tetrahymena
           thermophila SB210|Rep: oxidoreductase, short chain
           dehydrogenase/reductase family protein - Tetrahymena
           thermophila SB210
          Length = 338

 Score =  138 bits (334), Expect = 2e-31
 Identities = 91/311 (29%), Positives = 147/311 (47%), Gaps = 7/311 (2%)

Query: 1   MFVSFLFNRDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVK 60
           +F+  +  +++ +G    +     N  II+TG NSGIG    KD  + GAKV +A R+ +
Sbjct: 28  VFILLITVKNWVNGGKVSKRRDLSNEVIIVTGGNSGIGFETCKDLVRNGAKVILATRNEQ 87

Query: 61  KCEEQRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVME-PPK 119
           + +   +++     N   + +  DL+   SIR F   FK +   L+ L+NNAG+M    +
Sbjct: 88  RGQNAIKELNKIRPNSSEFMK-LDLSDLTSIRLFANEFKSKYNKLNCLINNAGIMAISTR 146

Query: 120 GVTKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN 179
            +TKDGFE+Q+G                 K              H R  I+  D+N S  
Sbjct: 147 VLTKDGFESQIGTNHFGHFLLTNLLFDVLKQTPQFRIINVSSRAHIRNTINLDDINFSNT 206

Query: 180 -YDASAAYSQSKLANLLFARELGRRLLGTGV--ATIAVDPGLVDTDITRHMSMMKSVTRF 236
            Y    AYS SK+AN+LF +EL ++     +    + + PG+V T++  H     ++   
Sbjct: 207 PYQKFYAYSASKIANILFTQELQKKFDAKKINGKAMCLHPGVVRTELASHFPYY-NIVYP 265

Query: 237 FIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMK-KAEPSQEAQDFELAQWLW 295
            +YP+    +K PE G QT +    +   K  +G YYVD K     ++ A   + A+ LW
Sbjct: 266 ILYPIALLLLKSPEAGAQTTLQCVHEDFSKLESGKYYVDCKVHPTGNKTALTTQNAERLW 325

Query: 296 RVSEAWTKLDE 306
            +S    KLD+
Sbjct: 326 DMSVKLVKLDQ 336


>UniRef50_A4BA05 Cluster: Short chain dehydrogenase; n=1; Reinekea
           sp. MED297|Rep: Short chain dehydrogenase - Reinekea sp.
           MED297
          Length = 302

 Score =  138 bits (334), Expect = 2e-31
 Identities = 89/287 (31%), Positives = 136/287 (47%), Gaps = 17/287 (5%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + R  I+TGAN G+G +     AK GA V MACR+  K      ++     +  +   P 
Sbjct: 11  EGRVAIVTGANVGLGFSTTHTLAKNGATVVMACRNADKANSAIAELKKNLPDADLVFMPL 70

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DL+   S++ F  +F  +   L +L+NNAGVM PP   T DGFE Q+G            
Sbjct: 71  DLSDLKSVKRFAEQFLEQFDRLDLLINNAGVMVPPYQKTVDGFELQMGANYFGHFLLTSL 130

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRR 203
                +              H+ G+IH  D++  + Y    AY QSKLA L+F+ EL RR
Sbjct: 131 LLPLLEKTGNARIVNLSSIAHRNGKIHFDDMHFEKRYSKMEAYGQSKLAMLMFSYELSRR 190

Query: 204 LLGTGVATIAV--DPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAAL 261
           L   G +TIAV   PG+ +T ++R++          + P+    +  PE G    ++AA+
Sbjct: 191 LKEQGYSTIAVAAHPGVANTALSRYLPKPMIA---LLTPVAGLLLSSPEEGALPQIYAAV 247

Query: 262 DPKLKDCAGDY-----YVDMK-----KAEPSQEAQDFELAQWLWRVS 298
              ++  +GDY     + +M+     K +P   A D E++  LW VS
Sbjct: 248 GEDIE--SGDYLGPNGFNEMRGKQPVKVKPRPHALDTEVSGRLWEVS 292


>UniRef50_A1ZGJ1 Cluster: Retinol dehydrogenase 14; n=1; Microscilla
           marina ATCC 23134|Rep: Retinol dehydrogenase 14 -
           Microscilla marina ATCC 23134
          Length = 285

 Score =  137 bits (332), Expect = 3e-31
 Identities = 81/283 (28%), Positives = 134/283 (47%), Gaps = 6/283 (2%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           ++  IITGAN+GIGK      AK+G  + M CR+  K EE +++I+ E+ N+ +    CD
Sbjct: 3   DKVCIITGANAGIGKETTLALAKKGTTIAMVCRNPNKAEETKKEIINESGNQNIEIFICD 62

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVME--PPKGVTKDGFETQLGVXXXXXXXXXX 142
            +  A I++         P + VL+NNAG +     +  T DG E  + V          
Sbjct: 63  FSIQAQIKKVAVELTQRYPAIDVLINNAGFIAAGTTRQTTPDGIEQTVAVNHLGYFMLTN 122

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR 202
                                H+       +L + + Y    AYS SKL N+ F   L +
Sbjct: 123 LLKPSLLASPTARIINVSSDAHKFIDFDINNLQLEQGYTPMKAYSISKLLNIHFTIALAK 182

Query: 203 RLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
           RL  T +   A+ PG+V T+ ++++S    V    I+ L  PFM  P  G  T ++ A  
Sbjct: 183 RLANTSITVNALHPGVVRTNFSKNLSGFTKV----IFALAKPFMINPVKGAATSIYLASS 238

Query: 263 PKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLD 305
           PK+ + +G Y+ + K+  P+++A +   A+ +W +S   T+L+
Sbjct: 239 PKVANISGKYFANKKQKTPNKDALNEAYAEKVWNMSIQLTQLE 281


>UniRef50_A3RPY6 Cluster: Short chain dehydrogenase; n=1; Ralstonia
           solanacearum UW551|Rep: Short chain dehydrogenase -
           Ralstonia solanacearum UW551
          Length = 292

 Score =  136 bits (330), Expect = 5e-31
 Identities = 85/274 (31%), Positives = 122/274 (44%), Gaps = 1/274 (0%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +  ++TGA  GIGKAA  +FAKRGA V +  R+ +K E    ++   + N  + C  CDL
Sbjct: 8   KVFLVTGATEGIGKAAVTNFAKRGATVTLIGRNKEKTERVVNELKAASGNHNLDCLVCDL 67

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           +  A +R     FK +   L VLVNNAG       +  DGFE    +             
Sbjct: 68  SRLADVRRAAEDFKAKHGRLDVLVNNAGATFKSPVIGPDGFELTFALNHLSHFQLPHSLF 127

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
              +                RG +  Q    S       AY+ SKLAN+LF +EL RRL 
Sbjct: 128 DLIRQTPGARVVSTSSGMQARGVLDLQKTPTSLEGPGWRAYATSKLANILFTKELQRRLE 187

Query: 206 GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKL 265
           GT       +PG V T      S +  +    +Y L  PF + PE G  +++  A   + 
Sbjct: 188 GTTATANCFEPGTVRTQFGAFGSDLGFLMN-LVYALARPFARTPEQGADSLIWLATSAEA 246

Query: 266 KDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
               G+Y  + +   PS +A+D +LA  LW +SE
Sbjct: 247 ASLRGEYVSNRRPVSPSSQARDPKLASDLWELSE 280


>UniRef50_Q7T348 Cluster: Zgc:64106; n=7; Euteleostomi|Rep:
           Zgc:64106 - Danio rerio (Zebrafish) (Brachydanio rerio)
          Length = 309

 Score =  135 bits (327), Expect = 1e-30
 Identities = 83/269 (30%), Positives = 129/269 (47%), Gaps = 5/269 (1%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYC 80
           VR   +T I+TGAN+GIGK  A DFA+RGA+V +ACR   +     ++I   T N  V+ 
Sbjct: 26  VRLKGKTAIVTGANTGIGKFIALDFARRGARVILACRSEARGTAALKEIRESTGNHDVHL 85

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXX 140
           R  D +S  S+R+F A+   EE  LH+LVNNAG    P  +T DG E             
Sbjct: 86  RLLDTSSMESVRKFAAQILKEEKELHILVNNAGASGLPIQITADGLEITFATNHVGPFLL 145

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE-NYDASAAYSQSKLANLLFARE 199
                   K              H +G +     +  + N+  +  Y+ +KL N+++  E
Sbjct: 146 TSLLLDLLKKSAPARIVNVASAMHWKGDVDFAHFHGEKLNHGVNRVYNHTKLHNVIWTNE 205

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
           L RRL GTGV   ++ PG+V T++ R+ +    + R     + + F K  E G  + ++ 
Sbjct: 206 LARRLQGTGVTANSLHPGVVMTEVMRNYNF---ILRLLFNLIGFFFFKTAEEGAFSPIYC 262

Query: 260 ALDPKLKDCAGDYY-VDMKKAEPSQEAQD 287
           A+  + +   G Y+  D     P+  A+D
Sbjct: 263 AVAEENEGITGKYFDSDCSLVLPAPPARD 291


>UniRef50_Q0VMN8 Cluster: Dehydrogenase/reductase; n=1; Alcanivorax
           borkumensis SK2|Rep: Dehydrogenase/reductase -
           Alcanivorax borkumensis (strain SK2 / ATCC 700651 / DSM
           11573)
          Length = 277

 Score =  135 bits (327), Expect = 1e-30
 Identities = 90/271 (33%), Positives = 124/271 (45%), Gaps = 7/271 (2%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           ++ ++ITG NSGIG   A+    RGA+V +ACRD  K +     I        +   P D
Sbjct: 2   SKRVLITGGNSGIGFCTAEQLVARGAEVILACRDQTKGQAAIAKIKNAHPQAKIRLFPLD 61

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           LA    +R+  A+   E  H+ VL+NNAGV+   +  TKDG+E Q GV            
Sbjct: 62  LADLEQVRDCAAQLYQELGHIDVLINNAGVVPTRQEFTKDGYEMQFGVNYLAPVLFTHLM 121

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
               K              H  GRI+K+     + Y    AY QSKLAN+LF+  L  RL
Sbjct: 122 LPLLKKGTAPRILHVASVAHWLGRINKKTWKGRKPYLIMDAYGQSKLANILFSNVLADRL 181

Query: 205 LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPK 264
              G+ + A+ PG VDT I RH+          I  L  P +  PE      V  ALD +
Sbjct: 182 KEIGITSNALHPGGVDTPIFRHVPNA-------IMALIRPTLTTPEKAASLPVSLALDKQ 234

Query: 265 LKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
                G+Y+ + K A  S  A++  LA  L+
Sbjct: 235 YVGITGEYFANHKTALRSPRARNSSLADELY 265


>UniRef50_UPI000155588C Cluster: PREDICTED: hypothetical protein;
           n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
           hypothetical protein - Ornithorhynchus anatinus
          Length = 352

 Score =  135 bits (326), Expect = 2e-30
 Identities = 88/270 (32%), Positives = 132/270 (48%), Gaps = 9/270 (3%)

Query: 27  TIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETN--NKYVYCRPCD 84
           T ++TGANSG+GK  A +  +RGA+V +ACRD+ + +E   DI   T    + +  R  D
Sbjct: 67  TAVVTGANSGLGKQVALELVRRGARVVLACRDLTRGQEALDDIRAATGCGPQRLLLREVD 126

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           L+S AS+R F AR   E P +H+LVNNAG+   P   T DG    L              
Sbjct: 127 LSSLASVRAFAARLLAELPEIHLLVNNAGIPGLPAR-TPDGLNVTLATNYLGPFLLTNLL 185

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE-NYDASAAYSQSKLANLLFARELGRR 203
               +              H+ G + ++ L+        S +Y  SKL  + F  ELGR 
Sbjct: 186 LEGLQRAGSARIVNVASFRHKFGFVDEEHLSRGGVQLTTSQSYDCSKLLLVAFTAELGRH 245

Query: 204 LLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDP 263
           L GTGV   +VDPG+V T+IT+++S    ++   + PLF    K P  G + +++  L  
Sbjct: 246 LQGTGVTANSVDPGVVVTNITKNLSRTWRLSFQLLRPLF----KSPAQGARNILYCCLAQ 301

Query: 264 KLKDCAGDYYV-DMKKAEPSQEAQDFELAQ 292
           +++   G Y+  D     P+  A D  LA+
Sbjct: 302 EVEGVTGKYFANDCTLQLPAAPACDTALAR 331


>UniRef50_UPI00003C0F00 Cluster: PREDICTED: similar to retinol
           dehydrogenase 11; n=3; Endopterygota|Rep: PREDICTED:
           similar to retinol dehydrogenase 11 - Apis mellifera
          Length = 326

 Score =  135 bits (326), Expect = 2e-30
 Identities = 94/288 (32%), Positives = 136/288 (47%), Gaps = 10/288 (3%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R  I+TGANSGIGK   K+ AKR A V +ACR+++       DI  + +   +     +L
Sbjct: 39  RVFIVTGANSGIGKETVKELAKRKATVILACRNIQTARNAISDIRTQISTGELVPMELNL 98

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPK--GVTKDGFETQLGVXXXXXXXXXXX 143
           AS +SI+EFV         +HVL+NNAGV  P K   +T DGFE   GV           
Sbjct: 99  ASFSSIKEFVTEVIKNFAEIHVLINNAGVYVPFKEQALTDDGFEIHFGVNHLGHFLLTNL 158

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENY----DASAAYSQSKLANLLFARE 199
                K               + G I   +LN  +        + AY  SKLAN  F  E
Sbjct: 159 LLEHLKQNGPNRIVIVTSKLFESGIIDFSNLNCEKGLVVKGRMNPAYCNSKLANTYFGIE 218

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIY-PLFWPFMKKPEIGGQTVVH 258
           L +R    G+    V PG   T + R++   +S   + I+ P+   F++    G QTV+H
Sbjct: 219 LAKRTKDNGINVYMVCPGFTYTGLFRNVK--RSWFHYIIFSPVALLFLRTANQGAQTVLH 276

Query: 259 AALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLDE 306
            A++P L + +G+ Y D  K   S++  D  +A  LW VS   T+++E
Sbjct: 277 CAIEPSLSNESGNIYRDC-KLYVSKKELDPNVALRLWDVSAKLTRINE 323


>UniRef50_Q1VVS7 Cluster: Short chain dehydrogenase; n=1;
           Psychroflexus torquis ATCC 700755|Rep: Short chain
           dehydrogenase - Psychroflexus torquis ATCC 700755
          Length = 299

 Score =  135 bits (326), Expect = 2e-30
 Identities = 99/290 (34%), Positives = 135/290 (46%), Gaps = 22/290 (7%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           N+ I+ITGA SG+GK A K  A + AKV +A R+ +K E+   +I  +  N  +  R  D
Sbjct: 16  NKVIVITGATSGLGKQATKVLASKNAKVILAVRNTQKAEDVVMEIRKDFPNAKLEIRHLD 75

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           L    S++ F   F  +   L VL+NNAG+M  P   T+DGFE Q+G             
Sbjct: 76  LGKLKSVQTFAEEFTSDYSQLDVLINNAGIMMCPYSKTEDGFEIQMGTNHFGHFALTGLL 135

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNM-SENYDASAAYSQSKLANLLFARELGRR 203
                              H+ G I+  D+N  S  Y    AYS SKLANL F  EL R+
Sbjct: 136 IPLLLETKDSRVVATSSIAHKSGSINFDDINWESRKYSTIKAYSDSKLANLYFTYELVRK 195

Query: 204 LLGTGVATI--AVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAAL 261
             G   A +     PG  +TD+ RHM    S+TR  + PLF    +  E G    + AA 
Sbjct: 196 YKGNPNAPLFTVAHPGGTNTDLGRHM----SITR-LLAPLFG---QNVETGTLPSLRAAT 247

Query: 262 DPKLKDCAGDYYVDMKKAE---------PSQEAQDFELAQWLWRVSEAWT 302
           D  L   +GDY+      E         P++ AQ+ E A+ LW +SE  T
Sbjct: 248 D--LNATSGDYFGPKSFFESRGYPVIVQPNKMAQNEENAKRLWEISEQLT 295


>UniRef50_Q9NZC7 Cluster: WW domain-containing oxidoreductase; n=37;
           Euteleostomi|Rep: WW domain-containing oxidoreductase -
           Homo sapiens (Human)
          Length = 414

 Score =  135 bits (326), Expect = 2e-30
 Identities = 94/283 (33%), Positives = 135/283 (47%), Gaps = 14/283 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + +++TGANSGIG   AK FA  GA V +ACR++ +  E    I+ E +   V     DL
Sbjct: 125 KVVVVTGANSGIGFETAKSFALHGAHVILACRNMARASEAVSRILEEWHKAKVEAMTLDL 184

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A   S++ F   FK +   LHVLV NA     P  +TKDG ET   V             
Sbjct: 185 ALLRSVQHFAEAFKAKNVPLHVLVCNAATFALPWSLTKDGLETTFQVNHLGHFYLVQLLQ 244

Query: 146 XXXKXXXXXXXXXXXXXXHQ-------RGRIHKQDLNMSEN-YDASAAYSQSKLANLLFA 197
                             H+        G++    L+ ++N Y A  AY++SKL N+LF+
Sbjct: 245 DVLCRSAPARVIVVSSESHRFTDINDSLGKLDFSRLSPTKNDYWAMLAYNRSKLCNILFS 304

Query: 198 RELGRRLLGTGVATIAVDPG-LVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTV 256
            EL RRL   GV + AV PG ++ ++I R   +        ++ L  PF K  + G  T 
Sbjct: 305 NELHRRLSPRGVTSNAVHPGNMMYSNIHRSWWVYT-----LLFTLARPFTKSMQQGAATT 359

Query: 257 VHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
           V+ A  P+L+   G Y+ +  +  PS EAQ  E A+ LW +SE
Sbjct: 360 VYCAAVPELEGLGGMYFNNCCRCMPSPEAQSEETARTLWALSE 402


>UniRef50_A1TDV9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium vanbaalenii
           (strain DSM 7251 / PYR-1)
          Length = 338

 Score =  134 bits (325), Expect = 2e-30
 Identities = 99/289 (34%), Positives = 126/289 (43%), Gaps = 10/289 (3%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYC 80
           V    +T +ITGA+SG+G+ +A+  AK GA V +A R+     E    +  +  +  +  
Sbjct: 36  VDLSGKTCVITGASSGLGRESARALAKAGAHVILAARNAAAMSETEAWLRAQLPDALLSV 95

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXX 140
              DL S ASI    A      P +HVL+NNAGVM  P G T DGFE Q G         
Sbjct: 96  VDLDLTSLASIAAAAAEISELTPVVHVLMNNAGVMFTPFGRTVDGFEIQFGTNHLGHFEL 155

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE-NYDASAAYSQSKLANLLFARE 199
                                  H+ G +   D N    +YD  AAY  SK AN+L A E
Sbjct: 156 TRLLFPALVAADGARVVNLSSEGHRMGDVDFDDPNWEHRDYDKFAAYGASKTANVLHAVE 215

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMS-------MMKSVTRFFIYPL--FWPFMKKPE 250
           L RRL  +GV   AV PG+V T + RHM+          S TR    P   F      PE
Sbjct: 216 LDRRLRDSGVRAFAVHPGIVATSLARHMTNDDFASLNAASSTRNSDKPATDFRKQFTTPE 275

Query: 251 IGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
            G  T V AA+   L D  G Y  D +    +  A D   A  LW +SE
Sbjct: 276 YGAATQVWAAVSTDLDDAGGVYLSDCEVRRAAAYAVDEARALALWDLSE 324


>UniRef50_UPI00006D02C7 Cluster: oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=1; Tetrahymena
           thermophila SB210|Rep: oxidoreductase, short chain
           dehydrogenase/reductase family protein - Tetrahymena
           thermophila SB210
          Length = 330

 Score =  133 bits (321), Expect = 7e-30
 Identities = 96/311 (30%), Positives = 132/311 (42%), Gaps = 7/311 (2%)

Query: 4   SFLFNRDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCE 63
           S    + Y++G           +T++ITG N GIGK  A D AKRGA+V +A R     +
Sbjct: 19  SLYLTKSYFNGGKCTVHRDLQGQTVLITGGNRGIGKETALDLAKRGARVVIASRSYDTLD 78

Query: 64  EQRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTK 123
             + +IV ++ N  V     DL    SIR F  +F  E   L +L+NNAGV       TK
Sbjct: 79  VVK-EIVKKSGNSKVEFVQLDLNDLQSIRNFAEKFNCENHRLDILINNAGVYNTRFSKTK 137

Query: 124 DGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGR-IHKQDLNMSEN--Y 180
           +GFE+  G+                               H R + I    LN   N   
Sbjct: 138 EGFESNFGINHLGHFLLTNLLLQKIVNTPQSRIVIVSSRAHTRSKTIDFDSLNQPTNSLI 197

Query: 181 DASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTR---FF 237
                Y QSKLAN LFA EL  +L GT    +++ PG++ + I +H        R     
Sbjct: 198 QELELYPQSKLANCLFATELVDKLKGTDTKVVSLHPGVIKSGIYQHNFSQLPFGRLIGLL 257

Query: 238 IYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRV 297
           +YP+     K    G QT +    +   K   G YY D +  + S  +QD ELA  LW  
Sbjct: 258 LYPISLLCFKSEYYGAQTTLTCCYEDFNKLVNGGYYKDNQLYKQSPVSQDKELANKLWDY 317

Query: 298 SEAWTKLDEHK 308
           S    KL+  K
Sbjct: 318 SLKAVKLENFK 328


>UniRef50_Q5YRJ5 Cluster: Putative short chain dehydrogenase; n=1;
           Nocardia farcinica|Rep: Putative short chain
           dehydrogenase - Nocardia farcinica
          Length = 326

 Score =  132 bits (320), Expect = 9e-30
 Identities = 94/278 (33%), Positives = 122/278 (43%), Gaps = 8/278 (2%)

Query: 23  ADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKK--CEEQRRDIVLETNNKYVYC 80
           AD +TI+ITGA SGIG AAA+    RG  + +  R+ +K    EQR   V       V  
Sbjct: 33  ADMKTILITGATSGIGSAAAEQLGARGEHLILVGRNPEKLAATEQR---VRAAGAGAVDT 89

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXX 140
             CD+ S A+IRE   + +     L VL NNAG   P + +T+DG ET   V        
Sbjct: 90  LRCDVGSQAAIRELAEQVRQRYDRLDVLANNAGGHFPDRALTEDGVETTFAVNYLGPFLL 149

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAREL 200
                                  H   R+   DL     Y    AYS+SKLA +L+ REL
Sbjct: 150 TELLLDLLLDSAPARVVFTSSVLHFGARLDLDDLPFEHGYTGEKAYSRSKLALILYTREL 209

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAA 260
            RRL GTGV   A  PG V T I   M             +   FM  PE G + + + A
Sbjct: 210 ARRLDGTGVTVNAFHPGAVATGIWDTMPWYGKPLAAIAKRI---FMISPEQGAEALTYLA 266

Query: 261 LDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
            DP++ D  G Y+   +  +P + A D EL   L  VS
Sbjct: 267 TDPEVADTTGCYFQRNRPKQPGRRATDDELGARLVEVS 304


>UniRef50_Q8LCE7 Cluster: Putativepod-specific dehydrogenase SAC25;
           n=28; root|Rep: Putativepod-specific dehydrogenase SAC25
           - Arabidopsis thaliana (Mouse-ear cress)
          Length = 331

 Score =  132 bits (320), Expect = 9e-30
 Identities = 94/291 (32%), Positives = 133/291 (45%), Gaps = 16/291 (5%)

Query: 19  RSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYV 78
           + + A N T IIT    GIG   A+  +KRGA V +  R++   E  + +I+ +  N  V
Sbjct: 27  QGIDATNLTAIITRGTGGIGMETARVLSKRGAHVVIGARNMGAAENAKTEILRQNANARV 86

Query: 79  YCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXX 138
                DL+S  SI+ FV  F      L++L+NNAGVM  P  +++DG E Q         
Sbjct: 87  TLLQLDLSSIKSIKAFVREFHALHLPLNLLINNAGVMFCPYQLSEDGIELQFATNHIGHF 146

Query: 139 XXXXXXXXXXKXXXXXX---------XXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQS 189
                     K                       +Q G I    +N   +Y    AY QS
Sbjct: 147 LLTNLLLDTMKNTAKTSGVEGRILNVSSVAHIYTYQEG-IQFDSINDICSYSDKRAYGQS 205

Query: 190 KLANLLFARELGRRLLGTGVATIA--VDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMK 247
           KLAN+L A EL R+L   GV   A  V PGL+ T++ +H +++    +FF + L W   K
Sbjct: 206 KLANILHANELSRQLQEEGVNITANSVHPGLILTNLFQHTALLMRFLKFFSFYL-W---K 261

Query: 248 KPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
               G  T  + AL P +K   G Y+ D  +  PS+ A+D  LAQ LW  S
Sbjct: 262 NIPQGAATTCYVALHPSVKGVTGKYFADCNEVTPSKLARDETLAQKLWDFS 312


>UniRef50_UPI00006CBD6F Cluster: oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=3; Tetrahymena
           thermophila SB210|Rep: oxidoreductase, short chain
           dehydrogenase/reductase family protein - Tetrahymena
           thermophila SB210
          Length = 328

 Score =  131 bits (317), Expect = 2e-29
 Identities = 93/279 (33%), Positives = 134/279 (48%), Gaps = 7/279 (2%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLET-NNKYVYCRPC 83
           N+ I+ITGANSGIG   AK+  + GAKV +ACRD  +   Q+  + L +   K       
Sbjct: 46  NQIIVITGANSGIGFETAKNCVQHGAKVVLACRD--EITAQQSCLQLNSIKKKSTEFIKL 103

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVME-PPKGVTKDGFETQLGVXXXXXXXXXX 142
           DL+ ++SIR+F   FK +   L +LVNNAGVM  P + +TK+GFE  +GV          
Sbjct: 104 DLSDSSSIRQFANIFKKKYSKLDILVNNAGVMAIPNRCLTKEGFEQTIGVNYFGHFLLTQ 163

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-YDASAAYSQSKLANLLFARELG 201
                 K              H  G I  QDL+ S+  Y    AY QSK+AN+LF   L 
Sbjct: 164 LLLDHLKLSSQFRVINVSSVAHLAGTIDFQDLHFSKRFYHGMLAYFQSKIANILFTISLQ 223

Query: 202 RRLLGTGVA--TIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
           ++     ++  ++++ PG+V T++ RH+  +  V    I PLF         G QT ++ 
Sbjct: 224 KKFDDQKLSGLSVSLHPGIVQTNLFRHLRGLTKVLFKLISPLFNFIYNNSFEGAQTTLYC 283

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
                 K   G YY D +K +        E A  LW +S
Sbjct: 284 IHQNYFKLEKGAYYSDCQKQKRLNNCITPENADILWNLS 322


>UniRef50_A7HAP1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Anaeromyxobacter sp. Fw109-5
          Length = 349

 Score =  131 bits (316), Expect = 3e-29
 Identities = 85/282 (30%), Positives = 123/282 (43%), Gaps = 1/282 (0%)

Query: 19  RSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYV 78
           RS     +  ++TGA SG+G   A + A+ GA V ++ R  + C  Q   I  ET  + V
Sbjct: 42  RSRELAGKCCLVTGATSGMGAVTALELARLGATVVVSGRSAESCASQAEAIRRETGAR-V 100

Query: 79  YCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXX 138
                DL S A +R   A        L VLVNNAG     + VT+DG E    V      
Sbjct: 101 ETAVADLGSLAQVRRMAAEVASRFERLDVLVNNAGTRLEQRSVTEDGLEKTFAVNYLSHF 160

Query: 139 XXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAR 198
                     +              H  G+I   +L    +Y+   AY++SKLA ++F  
Sbjct: 161 LLTNLLLDRLRASPAARVVNVASDAHALGKIELDNLQGERHYELMDAYARSKLAVVMFTY 220

Query: 199 ELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVH 258
           EL RRL GT V   AV PG+V T++       +   R  +  L    +  PE G + +V 
Sbjct: 221 ELSRRLEGTRVTVNAVHPGIVATNLGDENGFFQGWLRVRMRNLLKRSLLTPEEGARNIVR 280

Query: 259 AALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEA 300
            A  P+L+     Y+   ++   +  + D  LA+ LW VSEA
Sbjct: 281 LASAPELEGVTARYFDQDREVRSTPASYDAALAKRLWEVSEA 322


>UniRef50_Q0VQS4 Cluster: Oxidoreductase; n=1; Alcanivorax
           borkumensis SK2|Rep: Oxidoreductase - Alcanivorax
           borkumensis (strain SK2 / ATCC 700651 / DSM 11573)
          Length = 302

 Score =  130 bits (314), Expect = 5e-29
 Identities = 75/200 (37%), Positives = 100/200 (50%), Gaps = 2/200 (1%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +TI++TGANSGIG  A K F   GA+V MACR+  K E     + + T    +   P DL
Sbjct: 17  KTIVVTGANSGIGLEAVKLFVANGAEVIMACRNTAKAEAAAEQVKILTPQASLTVLPLDL 76

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A   S++ FVA  K     L VL+NNAGVM PP   TK+GFE Q G              
Sbjct: 77  ADLESVKTFVATLKQRINKLDVLLNNAGVMAPPLQRTKEGFEMQFGTNHLGHFALTGPLL 136

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL- 204
              +              H+ G+I   +LN  + Y   + Y QSKLANL+FA++L RRL 
Sbjct: 137 SLLEAAPAPRIVQISSLAHRGGKILWGNLNAEKRYSRWSFYCQSKLANLIFAKDLHRRLQ 196

Query: 205 -LGTGVATIAVDPGLVDTDI 223
             G+ +  +A  PG   T +
Sbjct: 197 KCGSSIQVMAAHPGYSATHL 216


>UniRef50_Q7VAC7 Cluster: Light dependent protochlorophyllide
           oxido-reductase; n=13; Cyanobacteria|Rep: Light
           dependent protochlorophyllide oxido-reductase -
           Prochlorococcus marinus
          Length = 315

 Score =  129 bits (311), Expect = 1e-28
 Identities = 78/253 (30%), Positives = 122/253 (48%), Gaps = 5/253 (1%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + RT+ +TGANSG+G   A+   ++GA V + CR ++K E  R+ ++ ET+   +     
Sbjct: 12  EGRTVFVTGANSGLGFDTAQALLEKGATVILGCRTLEKAERSRQKLLDETDCGKIDVLEI 71

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DLA    + E + +   +   L +L+NNAGVM PP+  +K GFE Q  V           
Sbjct: 72  DLADLEKVNEALDKIAVKYKKLDLLINNAGVMAPPQTFSKQGFELQFAVNHLSHMALTLK 131

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRR 203
                                  G+I+  DL   E YD  ++YSQSKLAN++FA EL +R
Sbjct: 132 LLPLIAKQPGSRVVTVSSGAQYMGKINLDDLQGGEGYDRWSSYSQSKLANVMFALELSKR 191

Query: 204 LLGTG--VATIAVDPGLVDTDI-TRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAA 260
           L  +   +A+++  PGL  T++ +  + +  S      Y L  P  +   +G    + AA
Sbjct: 192 LQQSNLDIASLSAHPGLARTNLQSTSVKLNGSWQEAIAYKLMDPMFQSSRMGALPQLLAA 251

Query: 261 LDPKLKDCAGDYY 273
            DP  K   G+ Y
Sbjct: 252 TDPTAK--TGEQY 262


>UniRef50_A4RTH5 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 320

 Score =  128 bits (310), Expect = 1e-28
 Identities = 92/289 (31%), Positives = 137/289 (47%), Gaps = 16/289 (5%)

Query: 23  ADNRTIIITGANSGIGKAAAKDF--AKRGAKVFMACRDVKKCEEQRRDIVLE--TNNKYV 78
           A  +T ++TGAN+GIG A  +    +   +K+ +ACRD  K       +  +   +   +
Sbjct: 17  ASRKTCVVTGANTGIGLATVRALRASNEYSKITLACRDASKARRAIDALARDGAASTCAL 76

Query: 79  YCRPCDLASTASIREFVARFKGEEPH--LHVLVNNAGVMEPPK-GVTKDGFETQLGVXXX 135
             R  DLAS AS R+F A +  +E    L  LVNNAGVM  PK   T+DGFE Q+GV   
Sbjct: 77  VFRELDLASVASARDFAASYLDDEGDDGLDCLVNNAGVMAVPKLERTRDGFELQVGVNHL 136

Query: 136 XXXXXXXXXXXXXKXXXXXXXXXXXXXXHQ-RGR-IHKQDLNMSENYDASAAYSQSKLAN 193
                                       H+  G+ + ++DL   +NY A   Y QSKLAN
Sbjct: 137 GHHALTAGLMPALAKSEDARVICVSSEAHRIAGKGLAREDLFGEKNYSAWGQYGQSKLAN 196

Query: 194 LLFARELGRRLLGTGVATI---AVDPGLVDTDITRHMSMMKSVTRFFIYPLF----WPFM 246
           +LFA EL RR    G+  +   A+ PG VD+++ R++       +++   L+      F+
Sbjct: 197 VLFAFELARRCERAGLGNVTASALHPGAVDSELGRYLQPPDEEIKWWQTKLYDFIRLNFL 256

Query: 247 KKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
           K  E G  T V  A +    +  G YY D  +  P++   D + A+WLW
Sbjct: 257 KTTEQGAATSVFLAREIARGEARGKYYSDCAEKTPAKNCLDVDDARWLW 305


>UniRef50_A5GU52 Cluster: Putative uncharacterized protein
           SynRCC307_1508; n=1; Synechococcus sp. RCC307|Rep:
           Putative uncharacterized protein SynRCC307_1508 -
           Synechococcus sp. (strain RCC307)
          Length = 304

 Score =  128 bits (308), Expect = 2e-28
 Identities = 85/251 (33%), Positives = 116/251 (46%), Gaps = 13/251 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R  ++TGAN+GIG  AA   A++GA+V + CRD ++ ++    I  E     V   P DL
Sbjct: 15  RLALVTGANTGIGYEAALQLARKGAQVLLGCRDEQRAKQAIERIQAEAPRGSVEWLPLDL 74

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A  AS+    A+ +     L +L+ NAGVM PP G T DGFE Q G+             
Sbjct: 75  ADLASVAAAAAQLRAAHQQLDLLICNAGVMVPPAGRTVDGFELQFGINHLGHFALVLQVL 134

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS-ENYDASAAYSQSKLANLLFARELGRRL 204
              +                 GR+   DLN     Y   AAY QSKLANLLF   L RRL
Sbjct: 135 PLLQAATAARVVAVSSGAALFGRMVFDDLNFERRGYQPWAAYGQSKLANLLFIEALARRL 194

Query: 205 --LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
              G+ V   A  PG+  T++ RH   M+++         W  M  P+ G    + AA D
Sbjct: 195 KRAGSSVVACAAHPGVTATELQRHSPNMQNMPA-------WLAMPAPQ-GALPSLRAATD 246

Query: 263 PKLKDCAGDYY 273
           P ++    DY+
Sbjct: 247 PGVEPL--DYF 255


>UniRef50_Q0S708 Cluster: Possible protochlorophyllide reductase;
           n=19; Actinomycetales|Rep: Possible protochlorophyllide
           reductase - Rhodococcus sp. (strain RHA1)
          Length = 292

 Score =  126 bits (304), Expect = 7e-28
 Identities = 102/298 (34%), Positives = 140/298 (46%), Gaps = 32/298 (10%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYC 80
           V    RT ++TGANSG+G+ AA+   K GA V +ACR+  K E   R I    +N  V  
Sbjct: 10  VDQSGRTFVVTGANSGLGEVAARALGKAGAHVVLACRNTHKGEVVARSI---GDNAEV-- 64

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXX 140
           R  DL+  AS+REF A   G E  + VLVNNAGVM  P+  T DGFE Q+G         
Sbjct: 65  RRLDLSDLASVREFAA---GVE-SVDVLVNNAGVMAVPQRTTADGFEMQIGTNHLGHFAL 120

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS-ENYDASAAYSQSKLANLLFARE 199
                                  HQ G IH  DLN     Y+  +AY QSKLANLLF  E
Sbjct: 121 TGLLL----DKITDRVATMSSAAHQAGTIHLDDLNWERRKYNRWSAYGQSKLANLLFTYE 176

Query: 200 LGRRL--LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVV 257
           L RRL   G+ V  +A  PG   T++  H   ++         +   F +  E+G   ++
Sbjct: 177 LQRRLSAAGSPVKAVAAHPGYASTNLQAHTESVQDKLMAVGNRI---FAQSAEMGALPML 233

Query: 258 HAALDPKLKDCAGDYYVD-----MKKAEP-----SQEAQDFELAQWLWRVSEAWTKLD 305
           +AA  P   D  G  Y+       ++  P     +++++D   A  LW +SE  T ++
Sbjct: 234 YAATAP---DVIGGSYIGPDGLFEQRGHPKVVGSNKKSRDEHTAGALWSLSEDLTGVE 288


>UniRef50_Q8XQU5 Cluster: Probable kog1208, dehydrogenases with
           different specificities (Related to short-chain alcohol
           dehydrogenases) oxidoreductase protein; n=3;
           Proteobacteria|Rep: Probable kog1208, dehydrogenases
           with different specificities (Related to short-chain
           alcohol dehydrogenases) oxidoreductase protein -
           Ralstonia solanacearum (Pseudomonas solanacearum)
          Length = 306

 Score =  124 bits (300), Expect = 2e-27
 Identities = 95/288 (32%), Positives = 126/288 (43%), Gaps = 20/288 (6%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAST 88
           I+TGAN+G+G   ++  A RGA+V +ACRD  K E     I        +   P DLA  
Sbjct: 21  IVTGANTGLGLETSRVLAARGARVLLACRDRSKAEAAMAHIRQTHPGADLAFLPLDLADL 80

Query: 89  ASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXXXX 148
           AS+R    +     P +  L+NNAGVM PP   T  GFE QLGV                
Sbjct: 81  ASVRAAAGQAM-TAPRIDALINNAGVMMPPLMRTTQGFELQLGVNHLGGFALTALLLPKL 139

Query: 149 KXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLLGTG 208
                          H+   I   DL+ +  Y+    Y  SKLAN LF  EL RRL  +G
Sbjct: 140 AQTPGSRVVVTSSLAHRGASIDWDDLSAATRYNRVKRYGASKLANALFFFELDRRLRASG 199

Query: 209 --VATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKLK 266
             V  +   PG   TD+ R+M  ++      + PL   F+    +G    + AA  P   
Sbjct: 200 SPVTAVGCHPGAAVTDLVRYMGALQ-----LLQPLVRRFLNTAAMGAWPTLQAATGPVQ- 253

Query: 267 DCAGDYY--VDMK-------KAEPSQEAQDFELAQWLWRVSEAWTKLD 305
              G YY    ++       +A  S +AQD  LAQ LW VS A T +D
Sbjct: 254 --PGGYYGPTGLRGIRGPSGRATRSAQAQDPLLAQRLWDVSIAMTGID 299


>UniRef50_A6QQ52 Cluster: MGC152281 protein; n=5; Theria|Rep:
           MGC152281 protein - Bos taurus (Bovine)
          Length = 330

 Score =  124 bits (298), Expect = 4e-27
 Identities = 86/283 (30%), Positives = 129/283 (45%), Gaps = 6/283 (2%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +T ++TGANSGIGKA +++ A RGA+V +ACR  ++ ++   +I   + +  +     DL
Sbjct: 50  KTAVVTGANSGIGKAVSQELAHRGARVILACRSRERGQQALAEIQATSKSNRLLLGEVDL 109

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           +S ASIR F  R   E P +H+LVNNA V   P  +T +G +                  
Sbjct: 110 SSMASIRSFAQRLLQECPEIHLLVNNAAVCGFPTTLTPEGLDLTFATNYTGPFLLTNLLQ 169

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDL-NMSENYDASAAYSQSKLANLLFARELGRRL 204
              +                 G I +  L         +  Y  SKL    F  +L +RL
Sbjct: 170 GALQRAGSARVVNVSSFRQSHGYIDEDHLIGAGRPLTFNQNYDCSKLLLASFTGKLAQRL 229

Query: 205 LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPK 264
            GT V   +VDPG+V T I +H S      RF  + L + F K  + G   V++ +L  +
Sbjct: 230 QGTVVTVNSVDPGVVYTKIMKHFSWS---YRFLFWLLSF-FFKDSKQGAVPVLYLSLAKE 285

Query: 265 LKDCAGDYYVDMKKAE-PSQEAQDFELAQWLWRVSEAWTKLDE 306
           L   +G ++        P + AQD  +AQ LW  S   T LD+
Sbjct: 286 LDGISGKHFSSSCVITLPPEAAQDPHVAQSLWNTSVRLTNLDK 328


>UniRef50_Q2IV76 Cluster: Short-chain dehydrogenase/reductase
           precursor; n=6; Bacteria|Rep: Short-chain
           dehydrogenase/reductase precursor - Rhodopseudomonas
           palustris (strain HaA2)
          Length = 309

 Score =  121 bits (292), Expect = 2e-26
 Identities = 85/282 (30%), Positives = 123/282 (43%), Gaps = 4/282 (1%)

Query: 22  RADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCR 81
           +A  RT +ITGANSG+GKA A   A   A+V +  RD ++ E    DI   T N  ++  
Sbjct: 5   QATKRTALITGANSGLGKAVATALAAEDARVGLVARDRERGETALADIRAATGNNDLHLF 64

Query: 82  PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX 141
             DLA  ++IR            LH+L+NNAG   P + ++ DG E    V         
Sbjct: 65  VADLADQSAIRALAQAVHRRFDRLHLLINNAGTAFPARRLSPDGIECAFAVNHLGPFLLT 124

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-YDASAAYSQSKLANLLFAREL 200
                  +                   +  +DLN     Y     Y QSKL NL F  EL
Sbjct: 125 NLLLDLLRASAPARIVNVGTRIST--ALDFEDLNWERRPYRMMQGYGQSKLGNLHFTFEL 182

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAA 260
            RRL G+GV    V PG+  +++        ++ + F     W  +  PE   + V++ A
Sbjct: 183 ARRLQGSGVTVNCVFPGVFKSNLGGTDGAQGALLKLFARWGGWA-IPSPERAARRVLYLA 241

Query: 261 LDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWT 302
             P+L   +G Y+ D K      +A D E  + LW++SEA T
Sbjct: 242 NAPELATVSGQYFGDRKIIPAPAQALDVEANRRLWQISEALT 283


>UniRef50_Q9RR99 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=3; Bacteria|Rep:
           Oxidoreductase, short-chain dehydrogenase/reductase
           family - Deinococcus radiodurans
          Length = 336

 Score =  121 bits (291), Expect = 3e-26
 Identities = 92/297 (30%), Positives = 124/297 (41%), Gaps = 16/297 (5%)

Query: 19  RSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYV 78
           R V    +T ++TG  SG+G   A+     GA V +  RD  K E    ++   T    V
Sbjct: 37  RGVDLKGKTAVVTGGASGLGTETARALLLAGAHVILPVRDRAKGERVAAELRQSTGGT-V 95

Query: 79  YCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXX 138
                DL S AS+R   A  +   P +H+L+NNAGVM  P+  T DGFETQ G       
Sbjct: 96  ELVDLDLGSLASVRRGAAEIRQLAPRIHILINNAGVMATPQSRTVDGFETQFGTNHLGHF 155

Query: 139 XXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-YDASAAYSQSKLANLLFA 197
                                    H+R  I   DLN     YD   AY QSK AN LFA
Sbjct: 156 LLTRELLPALMAAAPARVVALTSSGHRRSDIVWDDLNFERRPYDPWDAYGQSKTANALFA 215

Query: 198 RELGRRLLGTGVATIAVDPGLVDTDITRHMSM--MKSVTRFFIYPLFWPFMKKPEIGGQT 255
             L +R    G+   AV PG + T + + + +   + +     +    P  K P  G  T
Sbjct: 216 VGLTQRYADQGLTANAVHPGGIMTGLQKFVPLEDQRRMGWQDEHGTLNPVFKTPAEGAST 275

Query: 256 VVHAALDPKLKDCAGDYYVDMKKAEPSQE------------AQDFELAQWLWRVSEA 300
            V AA  P+L    G +  D++ + P  E            A D E A+ LW +SEA
Sbjct: 276 SVWAATSPQLYGVGGLFLEDLQHSTPLDESAPNPLFGYKPYALDHESARRLWALSEA 332


>UniRef50_Q6SHU1 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=1; uncultured
           bacterium 311|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family - uncultured bacterium
           311
          Length = 285

 Score =  121 bits (291), Expect = 3e-26
 Identities = 81/285 (28%), Positives = 129/285 (45%), Gaps = 9/285 (3%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + +  +ITGA SGIG++ A   +++GA +F   R+ +K EE   ++    + K       
Sbjct: 5   EGKNCLITGATSGIGRSTALALSEKGANIFFIARNQQKAEELTEEVE-RVSGKSPNAIIA 63

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DL+S   I      FK     + VL+NNAG+M   + VT+DG E    V           
Sbjct: 64  DLSSFKQIERAAEEFKSLNKPIDVLLNNAGIMNTERRVTEDGLEEVFAVNHLAYFLLTNL 123

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGR-IHKQDLNMSENYDASAAYSQSKLANLLFARELGR 202
                               H+  + ++  DL   + +   AAY QSKLAN+LF R+L  
Sbjct: 124 LIEKILESGLKRVVNVSSDAHRFLKSMNFDDLQSEKEFKMFAAYGQSKLANILFTRKLSS 183

Query: 203 RLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFW--PFMKKP-EIGGQTVVHA 259
                G+ T  + PG V T I            FF   + W  P + KP + G +T ++ 
Sbjct: 184 LYQEEGLTTNCLHPGFVSTSI----GAQNENLAFFARLIRWVSPLIAKPSDKGAETSIYL 239

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
               ++   +G+Y++D KKA  ++ A+  E A+ LW++S   T L
Sbjct: 240 CSSEEVSSTSGEYFIDCKKAPITKAAESKEDAEKLWQISLELTGL 284


>UniRef50_Q1GUJ0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Sphingopyxis alaskensis (Sphingomonas alaskensis)
          Length = 298

 Score =  121 bits (291), Expect = 3e-26
 Identities = 95/291 (32%), Positives = 132/291 (45%), Gaps = 22/291 (7%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R  ++TGAN+GIG   A+  A RGA V +ACRD +K E     I  + +   +     DL
Sbjct: 16  RRFLVTGANAGIGFEVARTLAARGAHVVLACRDAEKAEAAMARIRSDRSKADLSFLRLDL 75

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A    ++E  A      P + VLVNNAGVM PP+ +TK G E Q GV             
Sbjct: 76  ADLDQVKEAAAAVLA-GPRIDVLVNNAGVMIPPRTLTKQGHELQFGVNHLGTFAFTGLVH 134

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
              +              H+ G +   DL+ + +Y   A Y  SKLANLL   EL RRL 
Sbjct: 135 THIE----DRIVITGSIAHKSGEMDYSDLSATRSYHNWARYQMSKLANLLHMFELDRRLS 190

Query: 206 GTGVATIAV--DPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDP 263
             G AT A+   PG+  T++ RH+ +       ++ PL  PF      G    + AA   
Sbjct: 191 AAGRATQAIGCHPGVALTELQRHLPLPLR----YMTPLAAPFFNSAAQGAWPTLQAATGA 246

Query: 264 KLKDCAGDYY-------VDMKK--AEPSQEAQDFELAQWLWRVSEAWTKLD 305
            ++   GDY        V  +   A  S+ A+D +LA+ LW  S   T +D
Sbjct: 247 HVQ--GGDYLGPQGLGEVSGRSGPARASRAARDPKLARELWERSVELTGVD 295


>UniRef50_A7QX66 Cluster: Chromosome undetermined scaffold_213,
           whole genome shotgun sequence; n=6; Magnoliophyta|Rep:
           Chromosome undetermined scaffold_213, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 343

 Score =  120 bits (288), Expect = 6e-26
 Identities = 74/263 (28%), Positives = 119/263 (45%), Gaps = 8/263 (3%)

Query: 18  DRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKY 77
           D   + + +  I+TGANSGIG A A+  A RGA V+M CR+ ++ E    +I  +T N  
Sbjct: 54  DMQTQIEGKNCIVTGANSGIGYATAEGLASRGANVYMVCRNKERGEAALSEIQSKTGNSN 113

Query: 78  VYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXX 137
           V+   CDL+S + I+ F ++F  ++  +HVLVNNAG++E  +  T +GFE    V     
Sbjct: 114 VHLEVCDLSSVSEIKSFASKFSKKDVPIHVLVNNAGLLEYNRITTSEGFELNFAVNVLGT 173

Query: 138 XXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-YDASAAYSQSKLANLLF 196
                      +                       DL  S++ +D    Y+++K   +  
Sbjct: 174 FTMTESMLPLLEKAAPDARVITVSSGGMYSVPLTNDLQFSDDKFDGVTQYARNKRVQVAL 233

Query: 197 ARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTV 256
             +        G+   A+ PG  +T       + KS+  F  Y L    ++  E G  T+
Sbjct: 234 TEKWAEMYKNKGIGFYAMHPGWAETS-----GLAKSLPGF--YKLLSGNLRTIEEGADTI 286

Query: 257 VHAALDPKLKDCAGDYYVDMKKA 279
           +  AL PK K  +G +Y D  +A
Sbjct: 287 IWLALQPKEKLVSGAFYFDRAEA 309


>UniRef50_Q4WFI5 Cluster: Short-chain dehydrogenase/reductase,
           putative; n=12; Pezizomycotina|Rep: Short-chain
           dehydrogenase/reductase, putative - Aspergillus
           fumigatus (Sartorya fumigata)
          Length = 681

 Score =  120 bits (288), Expect = 6e-26
 Identities = 79/258 (30%), Positives = 118/258 (45%), Gaps = 8/258 (3%)

Query: 27  TIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLA 86
           +I+ITGA+SGIG   AK     GA +++  R++ K +    D+    ++  V+    DL 
Sbjct: 390 SILITGASSGIGVETAKALFTTGATLYLTARNLPKAKHALGDMA---SSPRVHLLELDLE 446

Query: 87  STASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX---- 142
           S AS+R   A+   +   L++ + NAGVM  P+G TKDGFETQLG               
Sbjct: 447 SLASVRACAAQLHSKTKTLNIFIANAGVMATPEGRTKDGFETQLGTNYLSHFLLFLLLRP 506

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR 202
                                H+   +   +LN+   YD   AY QSK A +  A E+ R
Sbjct: 507 ALLAAATPQANSRVVLLSSIAHRYSEVEFDNLNLDGQYDRWKAYGQSKCALVWAANEIDR 566

Query: 203 RLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
           R    G+   +V PG + T + +H+S  +  + F   P   P  K P+ G  T V AA+ 
Sbjct: 567 RYASRGLRAFSVQPGGIMTGLVQHLS-EEEQSGFTEDPTLGPQFKSPQQGAATSVWAAVS 625

Query: 263 PKLKDCAGDYYVDMKKAE 280
             L    G Y  +++ AE
Sbjct: 626 RSLDGMGGKYLENVQIAE 643


>UniRef50_A3KNN9 Cluster: MGC162294 protein; n=7; Euteleostomi|Rep:
           MGC162294 protein - Danio rerio (Zebrafish) (Brachydanio
           rerio)
          Length = 253

 Score =  119 bits (287), Expect = 9e-26
 Identities = 83/257 (32%), Positives = 118/257 (45%), Gaps = 6/257 (2%)

Query: 48  RGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHV 107
           RGA+V +ACRD +K  +  R+I   ++N  V     DLA+  SIREF   F  +E  L +
Sbjct: 2   RGARVIIACRDEEKARKAVREIKARSHNMNVLHMEVDLANMRSIREFSKTFLQKEKRLDI 61

Query: 108 LVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRG 167
           L+NNAG M      T D F    GV                K              ++  
Sbjct: 62  LINNAG-MPGVLDWTDDNFSMCFGVNHLGHFLLTNLLLPRLKESSPSRVINLTCSSYKYQ 120

Query: 168 RIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHM 227
           +++ QDLN   N      Y +SKLAN+ F +EL R + G GV   AV PG V +  T H 
Sbjct: 121 KLNFQDLNY--NLFPFFTYCRSKLANIYFTQELARMMEGKGVTAYAVHPGYVRSRWTCHF 178

Query: 228 SMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQD 287
           S++  +       + + F    E G QTVV+ A+  ++    G Y+ D + A     A+D
Sbjct: 179 SVLYQI---LAQVVMFMFFVSCEAGAQTVVYCAVSDEVLPRNGGYFTDCRPAPLKAFARD 235

Query: 288 FELAQWLWRVSEAWTKL 304
             +A+ LW  SE   KL
Sbjct: 236 SGVAKKLWEASERLVKL 252


>UniRef50_Q9L2C8 Cluster: Putative oxidoreductase; n=1; Streptomyces
           coelicolor|Rep: Putative oxidoreductase - Streptomyces
           coelicolor
          Length = 310

 Score =  118 bits (284), Expect = 2e-25
 Identities = 72/204 (35%), Positives = 95/204 (46%), Gaps = 6/204 (2%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           D R  ++TGAN G+G   A++ A++GA V +ACR  ++     R ++ E     V     
Sbjct: 13  DGRVAVVTGANGGLGYVIARELARKGATVVLACRSEERGSAAVRRLMGEVPAAAVEPARL 72

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DL   AS+REF      E   + +LVNNAGVM  P G T DGFETQ GV           
Sbjct: 73  DLGDLASVREFAYGLPYE--RVDLLVNNAGVMALPHGTTVDGFETQFGVNHLGHFALTGL 130

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRR 203
                               H   R+  +DLN    Y    AY++SK ANLLF  EL RR
Sbjct: 131 LLPSLLAAPGARIVTVSSVLHALARVDPRDLNSVRRYGRWTAYARSKSANLLFTHELARR 190

Query: 204 LLG----TGVATIAVDPGLVDTDI 223
           L G    + V  +A  PG  +T +
Sbjct: 191 LAGREGASDVRAVAAHPGYAETGL 214


>UniRef50_UPI000066053A Cluster: dehydrogenase/reductase (SDR
           family) member 13; n=1; Takifugu rubripes|Rep:
           dehydrogenase/reductase (SDR family) member 13 -
           Takifugu rubripes
          Length = 322

 Score =  118 bits (283), Expect = 3e-25
 Identities = 95/314 (30%), Positives = 137/314 (43%), Gaps = 41/314 (13%)

Query: 22  RADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACR----------DVKK---------- 61
           R   +T+I+TG+N+GIGK  A D A+RGA+V +ACR          DVK+          
Sbjct: 9   RLGGKTVIVTGSNTGIGKMTAIDLARRGARVILACRSRERGEAALADVKRVRPDQRVNGG 68

Query: 62  ----CEEQR-----RDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNA 112
               C  +R       ++ E+ +  V     DL S  S+R F   F   EP L +L+NNA
Sbjct: 69  RGLWCRSERVRVLSGSVLQESGSSQVVFMQLDLGSLKSVRSFAETFLRTEPRLDLLINNA 128

Query: 113 GVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQ 172
           GV    +G T+DG     GV                K              H  G I   
Sbjct: 129 GVYM--QGRTEDGLGMMFGVNHVGHFLLTHLLLDRLKQCGPSRVVNVASLAHNFGTIDFD 186

Query: 173 DLNMSE--NYDASAA-----YSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITR 225
            L   +    + S+      YS SKL N+LF  EL +RL GT V   ++ PG + +++ R
Sbjct: 187 CLTKHKALGLETSSTRVFKIYSDSKLCNVLFTHELAKRLEGTKVTCYSLHPGAIRSELAR 246

Query: 226 HMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEA 285
           + S    V +  I P+   F K    G QT +H AL   ++   G Y+ +    E   +A
Sbjct: 247 NTSW---VLQLLIVPMTAFFFKNTVQGAQTTLHCALQEGIEPLTGRYFSNCTVRELYPKA 303

Query: 286 QDFELAQWLWRVSE 299
           +D   A+ LW +SE
Sbjct: 304 KDDAAAKKLWELSE 317


>UniRef50_Q0S8U0 Cluster: Probable oxidoreductase, short chain
           dehydrogenase/ reductase family protein; n=3;
           Nocardiaceae|Rep: Probable oxidoreductase, short chain
           dehydrogenase/ reductase family protein - Rhodococcus
           sp. (strain RHA1)
          Length = 316

 Score =  118 bits (283), Expect = 3e-25
 Identities = 72/206 (34%), Positives = 99/206 (48%), Gaps = 3/206 (1%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RT+++TGAN+G+G  AA   A  GA V +ACR+ +        I    ++   +  P DL
Sbjct: 20  RTVLVTGANNGLGLHAATALAGAGATVLLACRNPQTGAAALTRIRKAGSDAEHHLIPLDL 79

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
              AS+R+      G  P + VL+NNAG+M  P G T DGFE Q+G              
Sbjct: 80  TDLASVRDAAQHACGVAPRIDVLINNAGLMAVPFGRTADGFELQIGTNHFGHFALTGQLL 139

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS-ENYDASAAYSQSKLANLLFARELGRRL 204
                             H+RGRI   DLN     Y    AY+QSKLANLLF+ EL RR 
Sbjct: 140 PALLGAPAPRVVTLASIAHRRGRIVLDDLNFDRRKYTRMGAYNQSKLANLLFSGELARRS 199

Query: 205 LGTG--VATIAVDPGLVDTDITRHMS 228
              G  + ++A  PG+  T++   M+
Sbjct: 200 AAAGLPLLSVATHPGIAATNLFDSMA 225


>UniRef50_Q8SZ46 Cluster: RE17220p; n=3; Diptera|Rep: RE17220p -
           Drosophila melanogaster (Fruit fly)
          Length = 406

 Score =  118 bits (283), Expect = 3e-25
 Identities = 97/326 (29%), Positives = 145/326 (44%), Gaps = 29/326 (8%)

Query: 16  PYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQ----RRDIVL 71
           P D  ++   + +++TG NSGIG   A+  A RG ++ +ACR+++  +      +R++  
Sbjct: 42  PNDNQIK--EQIVVVTGGNSGIGFEIAQALAGRGGRIILACRNLEAGKRAAAIIKRELGC 99

Query: 72  ET------------NNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPK 119
            T            +  +V  R  DL S  S+  F  +   E   + VLVNNAGV+    
Sbjct: 100 RTPLNSLDEDDNPEDRYFVEARYLDLCSLRSVHHFAGQLMAEFERIDVLVNNAGVVFANT 159

Query: 120 GV-TKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQD-LNM- 176
            + T+DGFE    V                +              HQ  +I   D LN+ 
Sbjct: 160 QMPTEDGFERHSQVNYLAPFLLTHLLLPHLQRSEQGRILFVSAHAHQGAKIDFDDPLNVG 219

Query: 177 --SENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLV-DTDITRHMSMMKSV 233
             S  + A  A++ SKL  LL  R + R L GT V      PGLV  T   R+  +M S+
Sbjct: 220 TWSVKFHAREAFAHSKLCVLLATRWMARELKGTSVTVNCCTPGLVRGTRHFRNSPLMSSL 279

Query: 234 -TRFFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQ 292
             +   YP  W FMK    G Q  +  A DP+LK+  G+Y+ D + A  S   QD ELA+
Sbjct: 280 CVKAVTYPWMWLFMKNAYEGAQCAIRLATDPQLKEVTGEYFNDCEIAASSVTGQDKELAK 339

Query: 293 WLW----RVSEAWTKLDEHKQAIAKD 314
            L+    +  E+ TKL   ++    D
Sbjct: 340 KLYMQTIKTLESVTKLTVDREEYGLD 365


>UniRef50_A0E897 Cluster: Chromosome undetermined scaffold_82, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_82,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 335

 Score =  117 bits (281), Expect = 5e-25
 Identities = 87/290 (30%), Positives = 128/290 (44%), Gaps = 20/290 (6%)

Query: 21  VRAD--NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLET-NNKY 77
           VR D   + ++ITG N+GIG   AK   + GA + + CRD+ K ++    I  E+  N+ 
Sbjct: 34  VRKDMTGKVVLITGGNAGIGAETAKKLGEMGADIIIGCRDLFKAQQILDQIRSESRGNQR 93

Query: 78  VYCRPCDLASTASIREFVARFKG-EEPHLHVLVNNAGVMEPPK-GVTKDGFETQLGVXXX 135
           +     DL     I  FV +FK     H+ VL+NNAG+M P +  ++K GFE Q G    
Sbjct: 94  LVMLKLDLTDLRDIDSFVQQFKALNIQHIDVLINNAGIMAPKEYKISKQGFEIQFGTNHI 153

Query: 136 XXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRG---RIHKQDLNMSENYD------ASAAY 186
                        K              H+      ++  D N   N           AY
Sbjct: 154 GHFYLGQKLLPFLKNSQNPRLVNVSSMAHKSSDGFDLNDLDCNRFANSSLWSTRYTLKAY 213

Query: 187 SQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHM-SMMKSVTRFFIYPLFWPF 245
           S SKL N+L A E  ++    G+   ++ PG+V TD+   +    + +  F IYP +W F
Sbjct: 214 SYSKLCNILHAMEFTKKY---GIPAYSLHPGVVRTDLFIEIYGGWRKIIYFLIYPFWWYF 270

Query: 246 MKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
            K PE G QT ++ +L+ K     G YY D     P    +  +LA  LW
Sbjct: 271 TKSPEQGAQTTLYLSLEDKENLQTGGYYKDCSLQTPMFANE--QLAAQLW 318


>UniRef50_A0PND0 Cluster: Oxidoreductase; n=4; Actinomycetales|Rep:
           Oxidoreductase - Mycobacterium ulcerans (strain Agy99)
          Length = 317

 Score =  116 bits (279), Expect = 8e-25
 Identities = 96/294 (32%), Positives = 137/294 (46%), Gaps = 22/294 (7%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAST 88
           I+TGANSG+G   A+  +  GA V MA R+  K E    +I     +  +  +  DL+S 
Sbjct: 18  IVTGANSGLGFGLARRLSAAGADVVMAIRNRAKGEAAIEEIRSAVPDAKLSTKALDLSSL 77

Query: 89  ASIREFVARFKGEEPHLHVLVNNAGVMEPP-KGVTKDGFETQLGVXXXXXXXXXXXXXXX 147
           AS+     +   E   + +L+NNAGVM PP +  T DGFE Q G                
Sbjct: 78  ASVAALGDQLNSEGRPIDILINNAGVMTPPERDTTADGFELQFGSNHLGHFALTAHVLPL 137

Query: 148 XKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR--RLL 205
            +               +RGRIH  DL   ++Y A  AY QSKLA L+FAREL R  R  
Sbjct: 138 LRAAQGARVVSLSSLAARRGRIHFDDLQFEKSYAAMTAYGQSKLAVLMFARELDRRSRAA 197

Query: 206 GTGVATIAVDPGLVDTDI----TRHMSMMKSVTRFFIYPLFW---PFM-KKPEIGGQTVV 257
           G GV + A  PGL  T++      H     ++ + F Y   W   PF+ ++ E G    +
Sbjct: 198 GWGVMSNAAHPGLTKTNLQISGPSHGREKPALMQRF-YTTSWRFAPFLWQEIEDGILPAL 256

Query: 258 HAALDPKLKDCA-----GDYYV---DMKKAE-PSQEAQDFELAQWLWRVSEAWT 302
           +AA+ P+ +  A     G Y      ++ A+ P++   D +  Q LW VSE  T
Sbjct: 257 YAAVTPQAEGGAFYGPRGFYEAAGGGVRAAKVPARAGNDAD-CQRLWEVSERLT 309


>UniRef50_A2BY70 Cluster: Short-chain dehydrogenase/reductase (SDR)
           superfamily; n=7; Prochlorococcus marinus|Rep:
           Short-chain dehydrogenase/reductase (SDR) superfamily -
           Prochlorococcus marinus (strain MIT 9515)
          Length = 309

 Score =  116 bits (278), Expect = 1e-24
 Identities = 71/251 (28%), Positives = 112/251 (44%), Gaps = 4/251 (1%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIV-LETNNKYVYCRP 82
           D +T+ ITGANSG+G   AK  A++ A V +ACR ++K       +  L    K+     
Sbjct: 22  DGKTVFITGANSGLGYYTAKALAEKNAHVVLACRTLEKANSALHKLKSLNPEGKFTPIE- 80

Query: 83  CDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX 142
            DLA    + E  ++   E   L +L+NNAG+M PPK ++  GFE Q  V          
Sbjct: 81  LDLADLNKVSEIGSKISTEFEKLDLLINNAGIMHPPKTLSPQGFEIQFAVNHLAHMLLTL 140

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR 202
                 +                 G++   +L     Y+   +Y+ SKLAN++FA EL  
Sbjct: 141 KFLPLIEKQKGSRIVTVTSGAQFFGKVGWNNLKAENYYNKWESYANSKLANVMFALELNE 200

Query: 203 RLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
           +L    + ++A  PG+  T++        +    F   LF P  +  E+G    + AA  
Sbjct: 201 KLEQKHILSLAAHPGIAKTNLFSAQKPKPNPIEIFSLELFSPIFQSAEMGALPQLFAATS 260

Query: 263 PKLKDCAGDYY 273
           P+ K   G++Y
Sbjct: 261 PQAK--GGEHY 269


>UniRef50_Q2UG97 Cluster: Dehydrogenases with different
           specificities; n=7; Pezizomycotina|Rep: Dehydrogenases
           with different specificities - Aspergillus oryzae
          Length = 333

 Score =  115 bits (277), Expect = 1e-24
 Identities = 78/263 (29%), Positives = 121/263 (46%), Gaps = 10/263 (3%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           ++ I+ITG +SG+G   AK     GA +++  RD+ K +    D+V   ++  V+    D
Sbjct: 40  DKVIMITGCSSGLGIETAKALFHTGATLYLTARDLGKAKTALGDLV---DSPRVHLLHLD 96

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX-- 142
           L S AS+R     FK +E  L++L+ +AGVM  P+G T DGFETQ G             
Sbjct: 97  LNSLASVRACAEEFKSKESTLNILIEDAGVMACPEGRTADGFETQFGTNHLAHFLLFYLL 156

Query: 143 --XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAREL 200
                                  H+   +H  ++ +   Y+   AY QSK AN+  A E+
Sbjct: 157 KPQFLSSSTFSFQSRLVVVASSAHRVSSVHFDNITLEGEYEPWKAYGQSKTANIWTANEI 216

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMS-MMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
            RR    G+   ++ PG + T++ RH+S   KSV  +        + K PE G  T V  
Sbjct: 217 ERRYGSQGLHAFSLHPGAIATELLRHVSDEQKSV--WDADDWLKKYWKSPEQGAATSVWG 274

Query: 260 ALDPKLKDCAGDYYVDMKKAEPS 282
           A+   L+   G Y  + + A P+
Sbjct: 275 AVARDLEGTGGKYLDNCQIASPA 297


>UniRef50_A6RTJ2 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 324

 Score =  115 bits (276), Expect = 2e-24
 Identities = 85/289 (29%), Positives = 127/289 (43%), Gaps = 15/289 (5%)

Query: 26  RTIIITGAN-SGIGKAAAKDFAK-RGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           +T +ITG    G+G   A   A  + A + +  RD  K       +   + +  V    C
Sbjct: 27  KTFVITGPTPGGLGVQTALQLAAAKPATILLLGRDESKAAPAVESVKAVSPSSTVRFVHC 86

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPK-GVTKDGFETQLGVXXXXXXXXXX 142
           DLA  +SI+          P +H L+NNAGVM PP    T +G E Q G           
Sbjct: 87  DLAKHSSIKTAAESILATTPKIHTLINNAGVMAPPDYRTTAEGLEIQFGANHVGHFLLTN 146

Query: 143 XXXXXXKXXXXXXXXXXXXXXH--QRGRIHKQDLNMSE--NYDASAAYSQSKLANLLFAR 198
                                     G +   D N ++  +YD  +AY QSK AN+LF  
Sbjct: 147 LLMPAIVAAASEGARIVNLSSQGWSLGEVRFDDYNFNDGKDYDRWSAYGQSKAANILFTV 206

Query: 199 ELGRRLLGTGVATIAVDPGLVDTDITRHM-------SMMKSVTRFFIYPLFWPFM-KKPE 250
           EL +RL   GV   A+ PG++D++++R +       +M +  T      +  PF+ K  E
Sbjct: 207 ELAKRLKSKGVQAFAIHPGVIDSNLSRDLDPATDYGAMAERFTSRGYIKMDGPFVWKSLE 266

Query: 251 IGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
            G  T + AALDP LKD +G Y  D +  E ++   + + A+ LW +SE
Sbjct: 267 QGTSTTLVAALDPALKDHSGVYLSDCQITETAEYTTNPDYAERLWELSE 315


>UniRef50_Q9XVS9 Cluster: Putative uncharacterized protein dhs-22;
           n=2; Caenorhabditis|Rep: Putative uncharacterized
           protein dhs-22 - Caenorhabditis elegans
          Length = 333

 Score =  114 bits (275), Expect = 2e-24
 Identities = 81/310 (26%), Positives = 133/310 (42%), Gaps = 6/310 (1%)

Query: 1   MFVSFLFNRDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVK 60
           +F+   F R Y+ G  ++  V A     ++TG+N GIG    ++   R A V+M CR  +
Sbjct: 22  VFIVLFFTRRYFKGGQFNERVSAKGLVAVVTGSNCGIGFETVRELNLRKADVYMLCRSEE 81

Query: 61  KCEEQRRDIVLE-TNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPK 119
           K  E +R +V +  +   ++   CDL    S+R            + +L+NNAG+M   K
Sbjct: 82  KANEAKRMLVRQGCDATRLHFIECDLTDFESVRRAAKETLESTDTIDILINNAGIMFQSK 141

Query: 120 -GVTKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRG-RIHKQDLNMS 177
              TKDG E                     K              H +  +I+   ++  
Sbjct: 142 HEQTKDGHEKTWQSNHLGPFLLTELFLPAVKKSSYARIINVSSRIHLKSEKINLATVDDK 201

Query: 178 ENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVD---PGLVDTDITRHMSMMKSVT 234
           +++    +Y QSKLAN++ AR L + L   G   + V+   PG+V+T++ R+  +     
Sbjct: 202 KSFGMMKSYRQSKLANVMHARALTKELRKDGAEHVTVNSLHPGVVNTELARNTILNTPGI 261

Query: 235 RFFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWL 294
           +       W  MK    G QT +  AL  K+   +G Y+ D K  + +  A D +  Q L
Sbjct: 262 KQITAVFRWFLMKTSRDGAQTSIFLALGKKIGGISGKYFADCKLTQENPLALDDQACQDL 321

Query: 295 WRVSEAWTKL 304
           +  S   T L
Sbjct: 322 YNYSLECTGL 331


>UniRef50_Q4S4S9 Cluster: Chromosome 2 SCAF14738, whole genome
           shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
           Chromosome 2 SCAF14738, whole genome shotgun sequence -
           Tetraodon nigroviridis (Green puffer)
          Length = 283

 Score =  114 bits (274), Expect = 3e-24
 Identities = 62/162 (38%), Positives = 83/162 (51%), Gaps = 1/162 (0%)

Query: 54  MACRDVKKCEEQRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAG 113
           M CRD++KCE   ++I   T N++VY    DL+S  SIREF  +   EE  + VL+NNAG
Sbjct: 1   MGCRDMEKCEATAKEIRGSTLNRHVYASQLDLSSLKSIREFAEKITKEEQRVDVLINNAG 60

Query: 114 VMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQD 173
           VM  P   T+DGF+ Q GV                K              H  G++  +D
Sbjct: 61  VMRCPAWKTEDGFDMQFGVNHLGHFLLTNLLLDKLKESAPSRVINLASLAHIVGKMDFED 120

Query: 174 LNM-SENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAV 214
           LN   + +D   AY QSKLAN+LF REL +RL G    ++ V
Sbjct: 121 LNWEKKKFDTKQAYCQSKLANVLFTRELAKRLQGKSTGSLHV 162



 Score = 55.2 bits (127), Expect = 2e-06
 Identities = 27/69 (39%), Positives = 39/69 (56%)

Query: 240 PLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
           P F   +K+PE+G Q VV+ A+   ++   G YY  M + EP+ +A D E+A  LW VS 
Sbjct: 214 PFFSLLVKRPELGAQPVVYLAVSDDMEGVTGKYYDVMTEKEPAPQALDEEVAHRLWEVSL 273

Query: 300 AWTKLDEHK 308
               LD+ K
Sbjct: 274 RLVGLDQEK 282


>UniRef50_A3WEU3 Cluster: Putative uncharacterized protein; n=1;
           Erythrobacter sp. NAP1|Rep: Putative uncharacterized
           protein - Erythrobacter sp. NAP1
          Length = 307

 Score =  114 bits (274), Expect = 3e-24
 Identities = 96/286 (33%), Positives = 127/286 (44%), Gaps = 17/286 (5%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           ++  +ITG NSGIG  AAK  A +   V +ACR  +K ++    +V E   +    R  D
Sbjct: 19  DKRFLITGGNSGIGFEAAKILASKNGDVVIACRSEEKGKQALAKLVNEGEGRCELLR-MD 77

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           LA  +SIR      K     +  LVNNAGVM+ PK  TKDGFE QLG             
Sbjct: 78  LADMSSIRAAADEAKDRFGAIWGLVNNAGVMQTPKFKTKDGFELQLGTNHLGHFLWTALM 137

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
                              H+ GRI   +L M   YD S AY +SKLANLLFA EL RRL
Sbjct: 138 MDQVDGRGGRVVTVASIA-HKFGRIDFDNLMMERGYDRSRAYLRSKLANLLFAMELHRRL 196

Query: 205 --LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
              G+ V ++A  PG   T +         ++R         F + P  G      AA D
Sbjct: 197 DAAGSKVKSVACHPGYSSTPLL--SKTQNPLSRIVNGVSSAVFAQSPVRGSWPTALAAAD 254

Query: 263 PKLKDCAGDYY-----VDMK----KAEPSQEAQDFELAQWLWRVSE 299
            + +  +G YY      D +     ++    A D  +A+ LW VSE
Sbjct: 255 DRAE--SGGYYGPTGFFDARGPVGDSDVEARALDETVAKRLWGVSE 298


>UniRef50_Q2N830 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=3;
           Bacteria|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein - Erythrobacter
           litoralis (strain HTCC2594)
          Length = 324

 Score =  113 bits (273), Expect = 4e-24
 Identities = 84/273 (30%), Positives = 119/273 (43%), Gaps = 12/273 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +T  ITG  SG+G+  A+  A +GA V +A RD++K      +I  +     V    CDL
Sbjct: 22  KTAFITGGYSGLGQETARAMAAKGAHVIIAGRDMEKANAAAEEIRGQVEGAQVDTIQCDL 81

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           AS  S+R   A  +     + +L+NNAGVM  P+  T DGFE Q G              
Sbjct: 82  ASLDSVRACGAEARERFDSIDLLINNAGVMACPQNETADGFEMQFGTNHLGHFLLTKELM 141

Query: 146 XXXKXXXXXXXXXXXXXXHQRGR----IHKQDLNM-SENYDASAAYSQSKLANLLFAREL 200
              +                RG     +H  D N  +  Y   A+Y QSK AN+LF+  L
Sbjct: 142 PLVEKGAGEGDGARIVNLSSRGHHIDDVHLDDPNFENREYQKWASYGQSKTANILFSVGL 201

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMS------MMKSVTRFFIYPLFWPFMKKPEIGGQ 254
             R    G+ +IAV PG + T++ RHM+      M K +       +   F   P+ G  
Sbjct: 202 ENRFGHKGITSIAVHPGGIQTNLGRHMTDEDRVWMRKRMKADSDEEMAKAFKSIPQ-GAA 260

Query: 255 TVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQD 287
           T  +AA +  L+   G Y  D   AE   E+ D
Sbjct: 261 TTCYAATEQSLQGHGGVYCEDCHVAEVDDESSD 293


>UniRef50_UPI0000D5714C Cluster: PREDICTED: similar to CG2070-PA;
           n=2; Tribolium castaneum|Rep: PREDICTED: similar to
           CG2070-PA - Tribolium castaneum
          Length = 320

 Score =  113 bits (272), Expect = 6e-24
 Identities = 77/280 (27%), Positives = 120/280 (42%), Gaps = 8/280 (2%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +T ++TGANSG+G     + A RG  V MA  DV   EE ++ I+  TNN  +  +  DL
Sbjct: 32  KTALVTGANSGLGYQTVLNLASRGCTVIMA--DVADMEESKKQIIKATNNPNIITKKIDL 89

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
            S  S+R F          L +L NNAG+   P   T DG+   + +             
Sbjct: 90  TSFKSVRNFATEILNSVDKLDILFNNAGIGVSPSDKTGDGYNPVMQINYFGHFLLTHLLI 149

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDA----SAAYSQSKLANLLFARELG 201
              K                   +  + L  +++ D+    +  Y  SKL  ++    L 
Sbjct: 150 DLLKRSAPSRIVSTSSLLAYTNNLSVKKLYETKSPDSTVPRTCLYGNSKLCLIIMTDILA 209

Query: 202 RRLLGTGVATIAVDPGLVDTDI-TRHMSMMK-SVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
            +L  TGV   +V PGLV T I T   +++K +   F    +   F K P  G QT++H 
Sbjct: 210 EKLKNTGVTANSVHPGLVTTPIFTNTYTVIKNNFLSFLSQTIHAFFAKDPWEGSQTMIHV 269

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
            +D  L++  G ++ D K     + A D E  + +W  +E
Sbjct: 270 GVDKNLENVTGKFFSDCKPFVKPRCAYDKEWCRKIWEETE 309


>UniRef50_A0JTU1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=7; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR - Arthrobacter sp. (strain
           FB24)
          Length = 279

 Score =  113 bits (272), Expect = 6e-24
 Identities = 86/285 (30%), Positives = 122/285 (42%), Gaps = 12/285 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RTI+ITGA+ GIG +AA+  AK G +V +  R  +K     R +  E    Y      D 
Sbjct: 4   RTIVITGASDGIGASAARTLAKAGEQVVVVGRSAEKT----RAVAQEIGADYFVS---DF 56

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A  + +R    + K + P + VL NNAG +   + +T DG E    V             
Sbjct: 57  ADLSQVRALAVQLKEKYPRIDVLANNAGGIMGKRELTVDGHEKTFQVNHLAPFLLTTELM 116

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
                             +  G +   DL+ +  Y  + AY  SKL N+LF  EL  R  
Sbjct: 117 DVL-TASNATVINTSSAANAFGYVDINDLDAAGKYSTNKAYGTSKLENILFTTELHHRYN 175

Query: 206 GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKL 265
             G++T A  PG V T+     +   S  RF    +   FM  PE G  T+V  A     
Sbjct: 176 NAGISTAAFHPGGVATNFAAEST---SWFRFAYKTIIKRFMLTPEQGADTLVWLATAKPG 232

Query: 266 KD-CAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLDEHKQ 309
           +D  +G YY     A+ +++A D ELA+ LW  SE     D+  Q
Sbjct: 233 QDWMSGAYYAKRALAKANKQAYDAELARRLWDRSEVLVSTDKLNQ 277


>UniRef50_UPI00015B6097 Cluster: PREDICTED: similar to CG11200-PA;
           n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
           CG11200-PA - Nasonia vitripennis
          Length = 350

 Score =  113 bits (271), Expect = 7e-24
 Identities = 93/309 (30%), Positives = 133/309 (43%), Gaps = 13/309 (4%)

Query: 3   VSFLFNRDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKC 62
           V  +F  + ++G       +   R  I+TG + GIG    +   +   +V +ACR     
Sbjct: 43  VKDMFWDNVHAGSNKTELPKMPGRVAIVTGGSRGIGTEVVRMLLQSDVEVVIACRRTSAG 102

Query: 63  EEQRRDI-VLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGV 121
           E+    I      +        D +S  S+R+FV  FK     L +LVNNAG+M  P G 
Sbjct: 103 EKAVESIRKCGVTSGKANVMELDNSSLDSVRKFVEEFKNNYQKLDILVNNAGIMFTPYGE 162

Query: 122 TKDGFETQLGVXXXXXXXXXXXXXXXXKXXXX----XXXXXXXXXXHQRGRIHKQDLNMS 177
           TKDGFE Q GV                K                  H  G I+ +D+N  
Sbjct: 163 TKDGFEEQYGVNYLSHFLLTVLLIPLLKNAGTADCFARVVNVSSCAHLLGDINFEDVNHK 222

Query: 178 ENYDASAAYSQSKLANLLFARELGRRLLGTGVATI--AVDPGLVDTDITRHMSMMKSVTR 235
             +   AAY+QSKLA LLF + L R      V  +  AV PG+V+T++  H S MK   +
Sbjct: 223 GYFVTGAAYAQSKLAQLLFTKRLTRLFEKKKVHVVANAVHPGIVNTELFDH-SYMK-YFK 280

Query: 236 FFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
            F   LF    K P  G   +V AA+ PK++  +G Y  +   +  +  A D  L   L+
Sbjct: 281 LFRQLLF----KSPTQGATPIVFAAVSPKIEGKSGMYIANCLDSPVNPLANDEALQDRLF 336

Query: 296 RVSEAWTKL 304
            +S    KL
Sbjct: 337 EISLKQVKL 345


>UniRef50_O53537 Cluster: Possible oxidoreductase; n=9; cellular
           organisms|Rep: Possible oxidoreductase - Mycobacterium
           tuberculosis
          Length = 317

 Score =  113 bits (271), Expect = 7e-24
 Identities = 71/198 (35%), Positives = 95/198 (47%), Gaps = 3/198 (1%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAST 88
           IITGANSG+G   A+  +  GA V MA R+  K E    +I     +  +  +  DL+S 
Sbjct: 18  IITGANSGLGFGLARRLSAAGADVIMAIRNRAKGEAAVEEIRTAVPDAKLTIKALDLSSL 77

Query: 89  ASIREFVARFKGEEPHLHVLVNNAGVMEPPKGV-TKDGFETQLGVXXXXXXXXXXXXXXX 147
           AS+     +   +   + +L+NNAGVM PP+ V T DGFE Q G                
Sbjct: 78  ASVAALGEQLMADGRPIDLLINNAGVMTPPERVTTADGFELQFGSNHLGHFALTAHLLPL 137

Query: 148 XKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR--RLL 205
            +               +RGRIH  DL    +Y    AY QSKLA L+FAREL R  R  
Sbjct: 138 LRAAQRARVVSLSSLAARRGRIHFDDLQFERSYAPMTAYGQSKLAVLMFARELDRRSRAA 197

Query: 206 GTGVATIAVDPGLVDTDI 223
           G G+ + A  PGL  T++
Sbjct: 198 GWGIISNAAHPGLTKTNL 215


>UniRef50_Q8YW93 Cluster: Alr1722 protein; n=6; Bacteria|Rep:
           Alr1722 protein - Anabaena sp. (strain PCC 7120)
          Length = 311

 Score =  112 bits (270), Expect = 1e-23
 Identities = 89/297 (29%), Positives = 136/297 (45%), Gaps = 19/297 (6%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R  I+TG++SGIG   A+  A + A V +A R++ K  +    I+ +  +  V     DL
Sbjct: 17  RLAIVTGSSSGIGYETARVLANKQASVIIAVRNLDKGNKALAKILQQNKDADVKLMELDL 76

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A+ AS++ F   F+     L +L+NNAGVM PP   T DGFE Q G              
Sbjct: 77  ANLASVKNFAENFRKNYLRLDLLINNAGVMIPPYSKTTDGFELQFGTNHLGHFALTGQLL 136

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE-NYDASAAYSQSKLANLLFARELGRRL 204
                             H  G+I   DLN  + +Y    AY  SKLANL F  EL R+L
Sbjct: 137 EFLISTEGSRIVNVSSGAHNMGKIDFDDLNWEQRSYAKWKAYGDSKLANLYFTYELDRKL 196

Query: 205 LGTGVATI--AVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
              G+ T+  A  PG   T++ R       + ++    L     +   +G    + AA++
Sbjct: 197 KDNGIDTLVTASHPGWTATELQRTAG---GIVKY----LNGIVAQDITMGALPTLRAAIE 249

Query: 263 PKLKDC---AGDYYVDMK----KAEPSQEAQDFELAQWLWRVSEAWT--KLDEHKQA 310
             LK       + +++M+    K E ++ ++D  LA+ LW VSE  T  K + +K+A
Sbjct: 250 AGLKGAEYFGPNGFMEMRGYPIKVESNELSKDQALAKKLWVVSEKLTDVKFEFNKKA 306


>UniRef50_Q399X9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=23; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia sp. (strain
           383) (Burkholderia cepacia (strain ATCC 17760/ NCIB 9086
           / R18194))
          Length = 328

 Score =  112 bits (270), Expect = 1e-23
 Identities = 90/291 (30%), Positives = 120/291 (41%), Gaps = 17/291 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +  ++TGANSG+G   A+  A +GA V M CRD  +  +    I     +  V   P DL
Sbjct: 15  KVAVVTGANSGLGWQLAETLAAKGATVVMGCRDAARAAQAADAIRRLHPDARVEVDPLDL 74

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A  ASI  F A        + +L NNAGVM  P   T DGFE Q G              
Sbjct: 75  ADLASIARFAADVAERHGRVDILCNNAGVMFLPLRHTHDGFEMQFGTNHLGHFALTGHLL 134

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
              +              ++ GRI   DL     Y+   AY  SKLANL+FA EL RR  
Sbjct: 135 PALRAARRARVVTMSSGLNRGGRIRVDDLRAEHRYNRYLAYCDSKLANLVFAIELQRRFE 194

Query: 206 GTGVA--TIAVDPGLVDTDIT-RHMSMMKSVTRFFIYPLFWPFMKKP-EIGGQTVVHAAL 261
               A  ++A  PG   T++     +M  S  R  +      ++ +P + G    +HAA 
Sbjct: 195 RAAFAGISVAAHPGYAATNLQFAGPAMDSSPARAALMRAANRYLAQPADQGALPAIHAAT 254

Query: 262 DPKLKDCAGDYYVDMK----------KAEPSQEAQDFELAQWLWRVSEAWT 302
            P   D AG  Y+              A   + A+D   A  LW  SEA T
Sbjct: 255 SP---DLAGGAYIGPSGLFESRGLPAPASVPRAARDVASAALLWEASEAAT 302


>UniRef50_Q89V05 Cluster: Dehydrogenase; n=4; Proteobacteria|Rep:
           Dehydrogenase - Bradyrhizobium japonicum
          Length = 312

 Score =  111 bits (268), Expect = 2e-23
 Identities = 93/300 (31%), Positives = 130/300 (43%), Gaps = 16/300 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RT ++TGA  G+G   A   A  GA V +  R+  K       I     +  +     DL
Sbjct: 15  RTAVVTGATGGLGYETAMALAGAGAIVILTGRNDAKGLRAIEGICERFPDALIAYEHLDL 74

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGV-TKDGFETQLGVXXXXXXXXXXXX 144
           AS +S+ +F  RF      L +LVNNAGVM  PK   T+DGFE QLG             
Sbjct: 75  ASLSSVADFAKRFAAGNEQLDLLVNNAGVMALPKRQQTEDGFEMQLGTNYLGHYALTARL 134

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
               +              H+ G I+  DL    +Y    AY QSKLA L+FA EL RR 
Sbjct: 135 LPQLRRAKASRIVNLSSLAHRSGAINFDDLQGKRSYRPWRAYCQSKLAMLMFALELQRRS 194

Query: 205 L--GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEI-GGQTVVHAAL 261
           L  G GV ++A  PG   TD+  +     +  ++ +     PF+ +    G    + AA 
Sbjct: 195 LAAGWGVTSVAAHPGYARTDLIAN-GPGANTLQWRVGRWLQPFISQSAAEGALPTLFAAT 253

Query: 262 DPKLKDCAGDYY-----VDMK----KAEPSQEAQDFELAQWLWRVSEAWTKLDEHKQAIA 312
            P  +   G YY      ++K     A+ + +A+DF  A  LW VS   T +     A+A
Sbjct: 254 SPAAE--PGGYYGPNRFYELKGPPAPAKITPQARDFAAAAMLWDVSATLTGVSFDDIAVA 311


>UniRef50_A4XSH7 Cluster: Short-chain dehydrogenase/reductase SDR
           precursor; n=3; Proteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR precursor - Pseudomonas
           mendocina ymp
          Length = 328

 Score =  110 bits (265), Expect = 4e-23
 Identities = 68/201 (33%), Positives = 97/201 (48%), Gaps = 3/201 (1%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + +++TG +SG+G   A   ++ GA+V +A R+ ++  E    I  +     +     DL
Sbjct: 38  KRMLVTGGSSGMGFEDALALSRAGAQVIIAARNSQRGAESIERIRAQVPQAQLRFEQLDL 97

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPP-KGVTKDGFETQLGVXXXXXXXXXXXX 144
           A  AS+R    R   E   L VL+NNA +M PP +GV++DGFE QL              
Sbjct: 98  ADLASVRSLAQRLNAEGEVLDVLINNAAIMAPPQRGVSRDGFEMQLATNFLGHFALTGLL 157

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
               +                RGRI   DL    +YD  AAY+QSKLA L+ A EL RR 
Sbjct: 158 LSSLRKSSDPRVVTLASIAVNRGRIDFDDLQSERSYDPYAAYAQSKLACLMMAFELQRRS 217

Query: 205 LGT--GVATIAVDPGLVDTDI 223
           L    GV +IA  PG+  T++
Sbjct: 218 LANNWGVRSIAAHPGVAVTEL 238


>UniRef50_Q7D3F2 Cluster: AGR_pAT_417p; n=5;
           Alphaproteobacteria|Rep: AGR_pAT_417p - Agrobacterium
           tumefaciens (strain C58 / ATCC 33970)
          Length = 310

 Score =  109 bits (263), Expect = 7e-23
 Identities = 90/294 (30%), Positives = 134/294 (45%), Gaps = 22/294 (7%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R+ ++TG   G+G   A   A+ G  V +A R+ +K  +    I     +  V     DL
Sbjct: 24  RSAVVTGTG-GLGLETALALARAGCDVTIAGRNPEKGSDAVSRIQRAAPHVTVSFEKLDL 82

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGV-TKDGFETQLGVXXXXXXXXXXXX 144
           A   SI  F  R + +   L +LVNNAG+M PPK   T+DGFE Q G             
Sbjct: 83  ADLTSIALFAQRMENDRESLDLLVNNAGIMVPPKRQETRDGFELQFGTNYLGHFALTAHL 142

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAREL--GR 202
               K               + G+I+  D+N  +NY    AYSQSKLA L+FA EL    
Sbjct: 143 MPLLKKGTDARVVTVSSVAARAGKINFADINSEKNYHPMRAYSQSKLACLMFALELQDRS 202

Query: 203 RLLGTGVATIAVDPGLVDTDITRH---MSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
           R  G GV++IA  PG+  TD+  +    + ++ + R F++ LF P  +    G    + +
Sbjct: 203 RAAGWGVSSIAAHPGVSRTDLLHNAPGRNSLQGLARTFLWFLFQPVAQ----GALPQLFS 258

Query: 260 ALDPKLKDCAGDYYVDMKKAE------PSQ---EAQDFELAQWLWRVSEAWTKL 304
           A   ++K  +G YY   +  E      P++   EA D    + LW +S+  T L
Sbjct: 259 ATSKEVK--SGGYYGPDRLGETRGHPQPARIPPEALDRVAGKQLWEISQRMTGL 310


>UniRef50_A0YBR7 Cluster: Short chain dehydrogenase; n=1; marine
           gamma proteobacterium HTCC2143|Rep: Short chain
           dehydrogenase - marine gamma proteobacterium HTCC2143
          Length = 305

 Score =  109 bits (263), Expect = 7e-23
 Identities = 82/288 (28%), Positives = 131/288 (45%), Gaps = 12/288 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + +++TGAN+GIG   A+  A  GA+V +ACR   K +     I    N+  V  +  DL
Sbjct: 25  KKVVVTGANTGIGYETARSLAVAGAEVVVACRSEDKGKSAVDAIQKCHNDVRVEFKKLDL 84

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           +S  S++ F      +   + V++ NAG++      T +G E  +GV             
Sbjct: 85  SSIESVKAFSENLSWDT--IDVIIGNAGLVPTNYQQTDEGIEQCVGVCHFGHFALCKLLL 142

Query: 146 XXXKXXXXXXXXXXXXXXHQRGR-IHKQDLNMSE-NYDASAAYSQSKLANLLFARELGRR 203
                             H+  + ++ +   +++ N+    AY Q+KL N+LF  EL RR
Sbjct: 143 PRLLKSKDPRVVMVSSESHRAPKKLNFKKFPLTKTNFAVFTAYGQAKLCNVLFVNELQRR 202

Query: 204 LLGTGVATIAVDPG-LVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
               G+   ++ PG L+ TDI R+  +        +  L  P  K P  G  T V+ A  
Sbjct: 203 FGDQGLNACSLHPGTLITTDIGRNSGLFS-----LLMTLISPLTKTPNQGASTTVYCAAY 257

Query: 263 PKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLDEHKQA 310
              KD  G Y+   K+ + S EA D E+A+ LW +SEA+   +EH  A
Sbjct: 258 INGKDMQGAYFSHCKRGKSSAEANDPEVAKHLWDISEAF--CEEHNVA 303


>UniRef50_UPI000058502F Cluster: PREDICTED: similar to CG2064-PA;
           n=7; Strongylocentrotus purpuratus|Rep: PREDICTED:
           similar to CG2064-PA - Strongylocentrotus purpuratus
          Length = 323

 Score =  109 bits (262), Expect = 9e-23
 Identities = 81/296 (27%), Positives = 131/296 (44%), Gaps = 19/296 (6%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEE---------------- 64
           V   ++TI++TGAN+GIG   AK  A+ GAKV +ACR   K  E                
Sbjct: 10  VNLADKTIVVTGANTGIGYETAKALAQAGAKVIVACRSESKATEAIEQMKKEHAEEKADP 69

Query: 65  QRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKD 124
           +++ + ++ ++  V     DL S  S   F+  +K +   LHVLV NAG+M  P+ +T D
Sbjct: 70  KKQRVQIKVDDINVEFMALDLGSLQSTMTFIEAYKSKGLPLHVLVCNAGIMWGPEELTSD 129

Query: 125 GFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQR-GRIHKQDLNMSENYDAS 183
           G+E    +                K                R    +  DL   +N D  
Sbjct: 130 GYEPHFQINYLSHFLLILHLLPVLKSSGPGARVVSVSSLMYRFASWNANDLQCLKNNDRG 189

Query: 184 AAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDI-TRHMSMMKSVTRFFIYPLF 242
             YS SK   ++    L +RL G+GV   ++ PG+V T++ TR    +   ++FF+  + 
Sbjct: 190 KRYSNSKCYQVMHMFSLAQRLEGSGVNIFSLHPGVVKTELATREGQQVPGSSKFFL-SVG 248

Query: 243 WPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
              ++ P  G  T +HAA +P   +    Y+   K    +  A++ E  + LW+ S
Sbjct: 249 SKMLRTPFDGALTSLHAAANPAYDEKTALYFDSSKPQSVNSMARNKEKQEILWKYS 304


>UniRef50_A5CQW0 Cluster: Putative short chain
           dehydrogenase/oxidoreductase; n=1; Clavibacter
           michiganensis subsp. michiganensis NCPPB 382|Rep:
           Putative short chain dehydrogenase/oxidoreductase -
           Clavibacter michiganensis subsp. michiganensis (strain
           NCPPB 382)
          Length = 309

 Score =  108 bits (259), Expect = 2e-22
 Identities = 70/206 (33%), Positives = 95/206 (46%), Gaps = 4/206 (1%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           D +  ++TG NSG+G   A+  A  GA V +  RD ++ E+    I       +V     
Sbjct: 13  DGKRAVVTGGNSGLGLETARRLAAAGASVVLTSRDPERGEDAAGTIRDRHPGVHVEVGSL 72

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPP-KGVTKDGFETQLGVXXXXXXXXXX 142
           DLA  AS+R F  R + E   + +LV+NAGVM PP +  T DGFE QLG           
Sbjct: 73  DLADLASVRAFADR-EIERGPIDILVDNAGVMAPPDRRETADGFEIQLGTNHLGHFALTG 131

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELG- 201
                 +              H  GRI   DL     Y A AAY Q+KLANLLF R L  
Sbjct: 132 LLLPALQAADAPRVVVVSSLAHWMGRIAFGDLQSERRYSAWAAYGQAKLANLLFMRRLQA 191

Query: 202 -RRLLGTGVATIAVDPGLVDTDITRH 226
                G G+  +A  PG+  T++ ++
Sbjct: 192 LSEERGWGLTAVAAHPGVTSTNLAKN 217


>UniRef50_A0Z3B2 Cluster: Alcohol dehydrogenase; n=1; marine gamma
           proteobacterium HTCC2080|Rep: Alcohol dehydrogenase -
           marine gamma proteobacterium HTCC2080
          Length = 291

 Score =  108 bits (259), Expect = 2e-22
 Identities = 78/275 (28%), Positives = 124/275 (45%), Gaps = 8/275 (2%)

Query: 28  IIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAS 87
           I+ITG  +GIG+A A   A +GA++ + CR++ K      +++        +    D+AS
Sbjct: 12  IVITGPTAGIGRATALSLALQGAQLTLLCRNLNKGLAVS-EVIESAGGLKPHLVQVDMAS 70

Query: 88  TASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX-X 146
             S+R   A        + VL+NNAG++   +  T DGFE  L V               
Sbjct: 71  LQSVRIAAASVLDLGLPIDVLLNNAGLINSYRRETPDGFEETLAVNHFAPFLLTGLLLPA 130

Query: 147 XXKXXXXXXXXXXXXXXHQRGR-IHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
                            H   + +   D+ + ++Y    AY +SKLAN+LF R L +RL 
Sbjct: 131 ILNAAPGARIVNVASGAHSFVKGMGFDDIQLQQSYKMFEAYGRSKLANILFTRTLSQRLA 190

Query: 206 GTGVATIAVDPGLVDTDI-TRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPK 264
             GV    + PG V TDI  +H  ++  +    I  L  PF + P+ G +T ++   D K
Sbjct: 191 EKGVTVNCLHPGAVATDIGKQHGELIAKI----IPILLKPFFRGPQKGAETSIYLCTDDK 246

Query: 265 LKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
           + D  G Y+ + K  +    A+D   AQ LW  ++
Sbjct: 247 VADQTGGYWYNCKLTKVKPWAKDDAQAQRLWNYTQ 281


>UniRef50_Q54BI7 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 298

 Score =  108 bits (259), Expect = 2e-22
 Identities = 75/292 (25%), Positives = 127/292 (43%), Gaps = 12/292 (4%)

Query: 22  RADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCR 81
           + +N+  IITG + GIGK   K  A+    + + CR+ +K E   ++I   T N  +   
Sbjct: 3   KLNNKVAIITGGSDGIGKETCKIIAREIGTIVIGCRNKQKGEVAAKEISSHTGNSNIIIL 62

Query: 82  PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX 141
             DL+   S++ FV  F      L +L+NNAGVM PP  +T+DG+  Q+           
Sbjct: 63  DLDLSKQNSVKSFVNEFNKLNLPLDLLINNAGVMCPPFSITQDGYSFQIATNHFGPFLLT 122

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGRI-----HKQDLNMSENYDASAAYSQSKLANLLF 196
                  +               +   +      K ++    NY+    YS SK  NLLF
Sbjct: 123 NLLLKNLEKSENPRILVLTSDRFKDADLSLILNDKINVESEANYNQLKDYSLSKCCNLLF 182

Query: 197 ARELGRRLL--GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQ 254
            +EL R+L+  G+ +   +++PG V T + R  + +  V  F + P F       ++  +
Sbjct: 183 TKELQRKLIEKGSKIVVNSINPGKVQTSLQRDFTGILKVA-FSLMPNF--IFTPIQVASK 239

Query: 255 TVVHAAL--DPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
                AL  DP L    G Y+      E  ++    E+++ LW ++  +T +
Sbjct: 240 ECAKVALGTDPSLNGIKGSYFNIGVLTETPRQFNSIEISKKLWDITSKFTNI 291


>UniRef50_Q16QL9 Cluster: Short-chain dehydrogenase; n=5;
           Culicidae|Rep: Short-chain dehydrogenase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 325

 Score =  108 bits (259), Expect = 2e-22
 Identities = 83/279 (29%), Positives = 116/279 (41%), Gaps = 12/279 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +  IITGAN+G+G    K    R A   MACR++ K  E    I  ET    +     DL
Sbjct: 42  KLFIITGANTGLGYETTKALTVRQATTIMACRNLSKASEAIDKIRQETKEGELIPMELDL 101

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           AS  SIR+F A+ K   P  + LVNNAG+       T++GFE   GV             
Sbjct: 102 ASFQSIRKFAAQIKDRYPDFYCLVNNAGLAAQEPAFTQEGFEVHFGVNHLGQFLLVDLLK 161

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDA--SAAYSQSKLANLLFARELGRR 203
              K                   I   +L     Y++  +  Y+ SKL N  +AREL +R
Sbjct: 162 DNLKKNNSRIVVVSSRMHEIEASIDIGNLGRWVEYNSRLNRLYNNSKLMNFYYARELYKR 221

Query: 204 LLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAA--- 260
             G  V  +   PGL  TD  R+    K        P+ W  ++  E G Q +++ A   
Sbjct: 222 --GFNVHVLC--PGLCHTDFFRNYD-PKWYHYLIFSPIVWLMLRSAEQGAQNIIYCATES 276

Query: 261 -LDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
             D K     G Y++   K   S+   D E+++ LW  S
Sbjct: 277 VTDEKRNPVTG-YFISNVKMRKSKYPFDEEISERLWNES 314


>UniRef50_A6RXH3 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 338

 Score =  108 bits (259), Expect = 2e-22
 Identities = 85/269 (31%), Positives = 117/269 (43%), Gaps = 14/269 (5%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAST 88
           +ITG +SGIG   A+  +  GA +++  R +   E    DI LE     V     DL+S 
Sbjct: 41  LITGCSSGIGVETARALSTTGATLYLTARKISTAEIALGDI-LEPGR--VEILEMDLSSL 97

Query: 89  ASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTK-DGFETQLGVXXXXXXXXXX----X 143
           A +R    +F  +   L+VLV NAG+M  P   T  DGFE Q GV               
Sbjct: 98  AGVRRGAEKFLRKSSKLNVLVCNAGIMAIPNYTTTVDGFEIQFGVNHLAHFLLFQLLKDT 157

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS---ENYDASAAYSQSKLANLLFAREL 200
                               H+ G I   D N +   E YD   +YSQSK AN+  A E+
Sbjct: 158 LLSSASPSFNSRVVVVSSASHRNGGIRLDDYNYTKRPEEYDLWGSYSQSKTANIYMANEI 217

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAA 260
            RR    G+   ++ PG + + ITRH+   K V  +         MK PE G  T V AA
Sbjct: 218 DRRYGQHGLHATSLMPGAIPSGITRHLD-PKDVAEYNATETMRKTMKSPEQGAATTVLAA 276

Query: 261 LDPKLKDCAGDYYVDMKKAE--PSQEAQD 287
           +  +L++  G Y  + + AE  PS    D
Sbjct: 277 IGKQLENKGGVYLENCEVAELYPSDRELD 305


>UniRef50_Q53877 Cluster: Ketoreductase; n=3; Streptomyces|Rep:
           Ketoreductase - Streptomyces sp. (strain C5)
          Length = 287

 Score =  107 bits (258), Expect = 3e-22
 Identities = 87/276 (31%), Positives = 117/276 (42%), Gaps = 14/276 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RT++ITGA SGIG+AAA   A++GA+V +  RD ++      + V  T          D 
Sbjct: 18  RTVLITGATSGIGRAAALAIARQGARVVLVGRDPERLRTVTNE-VARTAGPAPDAFRADF 76

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A    +RE   R +   P + V+  NAG M   +  T+DGFE  L V             
Sbjct: 77  AELRQVRELGERLRDRYPRIDVMAGNAGGMFWSRTTTQDGFEATLQV---NHLAGFLLAR 133

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-YDASAAYSQSKLANLLFARELGRRL 204
              +              + +GRI   DLN   + Y A  AY  SK AN++ A E  RR 
Sbjct: 134 LLRERLAGGRLILTSSDAYTQGRIDPDDLNGDRHRYSAGQAYGTSKQANIMTATEAARR- 192

Query: 205 LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPK 264
               V T++  PG V T I R        T    Y  F PF++    G  T+V  A  P 
Sbjct: 193 -WPDVLTVSYHPGEVRTRIGRG-------TVASTYFRFNPFLRSAAKGADTLVWLAAAPA 244

Query: 265 LKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEA 300
            +   G YY D + +  S    D  LA  LW  S A
Sbjct: 245 EELTTGGYYSDRRLSPVSGPTADAGLAAKLWEASAA 280


>UniRef50_Q9VLU5 Cluster: WW domain-containing oxidoreductase; n=8;
           Endopterygota|Rep: WW domain-containing oxidoreductase -
           Drosophila melanogaster (Fruit fly)
          Length = 409

 Score =  107 bits (258), Expect = 3e-22
 Identities = 79/283 (27%), Positives = 125/283 (44%), Gaps = 16/283 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCR--PC 83
           RT +ITGAN GIG   A+  A  G ++  ACR+    E     I  E       CR    
Sbjct: 122 RTALITGANCGIGYETARSLAHHGCEIIFACRNRSSAEAAIERIAQERPAARSRCRFAAL 181

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DL+S  S++ FV   K    H+  L+ NAGV   P   T DG ET   V           
Sbjct: 182 DLSSLRSVQRFVEEIKQSVSHIDYLILNAGVFALPYTRTVDGLETTFQVSHLSHFYLTLQ 241

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNM------SENYDASAAYSQSKLANLLFA 197
                               H+   +  ++L +       E Y +  AY+ +KL N+LFA
Sbjct: 242 LETL--FDYKTRIIVLSSESHRFANLPVENLAVHHLSPPPEKYWSMMAYNNAKLCNVLFA 299

Query: 198 RELGRRLLGTGVATIAVDPG-LVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTV 256
           +EL +R    G++  ++ PG +V +D++R+    +      ++ +  PF K  +    T 
Sbjct: 300 QELAQRWKQRGISVFSLHPGNMVSSDLSRNYWFYR-----LLFAIVRPFTKSLQQAAATS 354

Query: 257 VHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
           ++ A   +L   +G Y+ +    EPS+ ++   L Q LW++SE
Sbjct: 355 IYCATANELTGLSGLYFNNCFFCEPSKLSKSAALQQQLWKLSE 397


>UniRef50_Q7K0F7 Cluster: GH19857p; n=4; Diptera|Rep: GH19857p -
           Drosophila melanogaster (Fruit fly)
          Length = 355

 Score =  107 bits (257), Expect = 4e-22
 Identities = 86/291 (29%), Positives = 126/291 (43%), Gaps = 15/291 (5%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIV-LETNNKYVYCRPC 83
           +R  +ITG N GIG    +        V M  RD K  E     IV L      + C   
Sbjct: 67  DRIAVITGGNRGIGLRIVEKLLACDMTVVMGVRDPKIAETAVASIVDLNATKGKLICEQL 126

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           D+    S++ F    K     + +L+NNAG+M  P  +T DG+E+   +           
Sbjct: 127 DVGDLKSVKAFAQLIKERYSKVDLLLNNAGIMFAPFKLTADGYESHFAINFLGHFLLTHL 186

Query: 144 XX----XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                    K              +  GRI+ +D+N +++Y    AYSQSKLA +LF R 
Sbjct: 187 LLPQLRAAGKEGRNSRIVNVSSCVNLIGRINYKDINGTKHYYPGTAYSQSKLAQILFTRH 246

Query: 200 LGRRLLG--TGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWP-FMKKPEIGGQTV 256
           L   L    + V    V PG+VDTD+  H S   SV      P+F   F K PE G +TV
Sbjct: 247 LQTLLDAEKSHVQVNVVHPGIVDTDLFEH-SATTSV------PIFKKLFFKTPERGSRTV 299

Query: 257 VHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLDEH 307
           V AA+DP ++   G Y  +  K     +A+     + L++ S    K+ ++
Sbjct: 300 VFAAIDPSIEGQGGTYLSNGGKGPFHPDAKKPAKCEQLFQFSCDLLKIQQY 350


>UniRef50_UPI000058766F Cluster: PREDICTED: similar to WW
           domain-containing oxidoreductase; n=3;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           WW domain-containing oxidoreductase - Strongylocentrotus
           purpuratus
          Length = 410

 Score =  107 bits (256), Expect = 5e-22
 Identities = 83/274 (30%), Positives = 117/274 (42%), Gaps = 12/274 (4%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAST 88
           IITGANSGIG   A   A  G  V +ACRD+K   +    I    +   V     DLAS 
Sbjct: 126 IITGANSGIGFETALGMALHGVHVVLACRDLKSGNDAASKIKKRLDQAKVVVMQLDLASL 185

Query: 89  ASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXXXX 148
            SI++F   +   E  LH+LV NAG+   P  +T+D  E    V                
Sbjct: 186 RSIQQFARNYTLREWPLHMLVCNAGIFGAPWELTEDKIEMTFQVNHVGHFHLVNLLTETL 245

Query: 149 KXXXXXXXXXXXXXXHQRGRIHKQDLNMSE------NYDASAAYSQSKLANLLFARELGR 202
           K              H+    +   L++SE       +    AY +SKL N+L + EL R
Sbjct: 246 KKSAPARIVMVSSESHRFIDFYSNKLDLSEVAMPKDKFWPILAYGRSKLCNILHSNELNR 305

Query: 203 RLLGTGVATIAVDPG-LVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAAL 261
           RL    V   A+ PG ++ T I+++    +      ++ +  PF K    G  T +  A 
Sbjct: 306 RLSPHNVTCNALHPGNMIYTGISKNWWPYR-----IMFLMVRPFTKSATQGASTSMFCAT 360

Query: 262 DPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
             +L+   G Y+       PS EAQ+ ELA  LW
Sbjct: 361 ARELEGVGGMYFNHCCACMPSDEAQNTELATALW 394


>UniRef50_A4AEV0 Cluster: Short chain dehydrogenase; n=1; marine
           actinobacterium PHSC20C1|Rep: Short chain dehydrogenase
           - marine actinobacterium PHSC20C1
          Length = 316

 Score =  107 bits (256), Expect = 5e-22
 Identities = 80/257 (31%), Positives = 115/257 (44%), Gaps = 17/257 (6%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC-- 83
           +  I+TGANSG+G A ++     GA V M  R  +K    +  +V    N          
Sbjct: 18  KVAIVTGANSGLGLATSRALLAAGAHVVMTTRTSEKAATAQAAVVESLGNAAAVAETMLL 77

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DLA   SIR F   F G+   L +L+NNAG+M     +T DGFE+QLG            
Sbjct: 78  DLADLESIRRFSEEFHGKHSRLDLLINNAGIMMTDAQLTIDGFESQLGTNHLGHFALTGR 137

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE-NYDASAAYSQSKLANLLFARELGR 202
                +              H+ G +   +L     +Y   AAY +SKLANLLFA EL R
Sbjct: 138 LLDLIESTPGARVVSLSSVAHRWGFMEFGNLMFQNGSYTPRAAYGRSKLANLLFAYELQR 197

Query: 203 RLLGTGV--ATIAVDPGLVDTDITRHMSMMKSVTRFFIYP---LFWPFMKKPEIGGQTVV 257
           R    GV   ++A  PG   T +  H+       R+++ P   L +  ++ P  G +  +
Sbjct: 198 RFDAAGVDALSVAAHPGTAGTGLADHL-----FNRWYLRPLKSLLFLGIQTPRQGARPTL 252

Query: 258 HAALDPKLKDCA-GDYY 273
            AA D   +D A GD++
Sbjct: 253 RAATD---EDAAGGDFF 266


>UniRef50_A0B1Z9 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Burkholderia cenocepacia|Rep: Short-chain
           dehydrogenase/reductase SDR - Burkholderia cenocepacia
           (strain HI2424)
          Length = 301

 Score =  107 bits (256), Expect = 5e-22
 Identities = 91/285 (31%), Positives = 125/285 (43%), Gaps = 9/285 (3%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R I+ITGANSG GK A +     GA V MA R   K +  RRDI  E     +  R  DL
Sbjct: 10  RRIVITGANSGTGKEATRRLVAAGADVIMAVRSESKGDAARRDIRKEFPGTSIEVRTLDL 69

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGV-TKDGFETQLGVXXXXXXXXXXXX 144
           +S AS+R F  +   E   L VLVNNAG+M PP  V + DGFE QL              
Sbjct: 70  SSLASVRNFGRQLLEEGRPLDVLVNNAGIMMPPTRVLSSDGFELQLATNFLGHFALTNLL 129

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR-- 202
                                   I+  DL    +Y    AY+QSKLA LL A  L    
Sbjct: 130 LPLLLEAKSPRVATMTSSAAMGATINFDDLQGERSYKPMTAYAQSKLACLLLANRLAEIA 189

Query: 203 RLLGTGVATIAVDPGLVDTDI-TRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAAL 261
           R  G  + + +  PG   T++ T   +M    TR  +     P M   E    +++ AA+
Sbjct: 190 RERGWPLLSTSAHPGHTRTNLQTSGPNMGTDSTRKRLSFRLVPSM-DVEWATDSLLRAAV 248

Query: 262 DPKLKDCA--GDYYVDMKKAEPSQEAQDFELAQ--WLWRVSEAWT 302
           DP     A  G  ++ +  +  +++ +  + A    LW+V+EA T
Sbjct: 249 DPTATQGAFYGPRFLLVGNSHVAKQPRSAKSADSIRLWQVAEALT 293


>UniRef50_Q4WLK4 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=5; Trichocomaceae|Rep:
           Oxidoreductase, short-chain dehydrogenase/reductase
           family - Aspergillus fumigatus (Sartorya fumigata)
          Length = 743

 Score =  106 bits (255), Expect = 6e-22
 Identities = 80/289 (27%), Positives = 127/289 (43%), Gaps = 32/289 (11%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLE------------ 72
           ++ I ITG +SG+G A A+  +   A +F+A RD  K      D++              
Sbjct: 421 DKVIFITGCSSGLGAATARALSNTNATLFLAVRDTPKARHVLADLLASASDSDSGSRLAS 480

Query: 73  -------------TNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPK 119
                        T+   +     DLAS +SIR  V  F  +   L++L+NN GVM  P+
Sbjct: 481 DADGKCSTSTSTSTSQSEIRLLHMDLASLSSIRHAVTSFLSQSDKLNILINNGGVMATPE 540

Query: 120 GVTKDGFETQLGVXXXXXXXXXXXXXXXXKXXXX----XXXXXXXXXXHQRGRIHKQDLN 175
             T+DGFETQ G                                    H++  I   DL+
Sbjct: 541 SRTEDGFETQFGTNHLGHFLLFQLLKPLLLRSATPQFHSRVVSVTSSAHRKSGIRFGDLH 600

Query: 176 M-SENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVT 234
             +E YD + AY+QSK AN+    E+ RR  G G+  ++V PGL+ T + + +    ++ 
Sbjct: 601 FETEKYDGALAYAQSKTANIYMMNEIERRFGGQGLHGLSVHPGLILTGLQKFVD--DALM 658

Query: 235 RFFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQ 283
             +  P   P++K  E G  TVV AA+  + +   G Y  D +++ P++
Sbjct: 659 EEWRKPGMRPYLKTEEQGAATVVVAAVGREWEGKGGKYLEDCRESGPAK 707


>UniRef50_Q3WJ13 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 271

 Score =  106 bits (254), Expect = 9e-22
 Identities = 82/279 (29%), Positives = 118/279 (42%), Gaps = 23/279 (8%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RTI++ GA SG+G+ AA    + G ++ +  RD K+  +   D+   T          D+
Sbjct: 2   RTIVLVGATSGLGRHAAHILKEAGHRLVLVGRDPKRAAQLAHDLPTAT------VIAADI 55

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           ++ A I     +       +  LVNNAGVM P +  T +G E  L V             
Sbjct: 56  STAAGIDLVAEKVHAVVDRVDTLVNNAGVMLPTRRTTSEGIELNLAVHHLAPYSTTARLL 115

Query: 146 XXXKXXXXXXXXXXXXXXHQ----RGRIHKQ--DLNMSENYDASAAYSQSKLANLLFARE 199
              +                     G +H    DLN    YD    YS++KLANLLF  E
Sbjct: 116 PLLRHGDGRIINVNSEGHRAPMRGAGPVHLDLTDLNSERRYDPFLTYSRTKLANLLFTYE 175

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
           L RR     VA  AV PG+V T++ RH   ++         L  PFM  P  G + V+H 
Sbjct: 176 LQRRHPELTVA--AVHPGMVRTNLGRHFPRLR-------VALLLPFMMSPRQGARPVIHL 226

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           A  P +   AG YY  ++    S  + D   A+ LW ++
Sbjct: 227 ASAPTIS--AGRYYDRLRPVSSSPASYDTNTARRLWEIT 263


>UniRef50_Q39N41 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=6; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Burkholderia sp. (strain 383) (Burkholderia
           cepacia (strain ATCC 17760/ NCIB 9086 / R18194))
          Length = 321

 Score =  105 bits (251), Expect = 2e-21
 Identities = 86/295 (29%), Positives = 120/295 (40%), Gaps = 20/295 (6%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           D +T I+TG +SG+G    +  A+ GA V +  R+     E  R I        V     
Sbjct: 28  DGKTAIVTGGHSGLGLETTRALAQAGATVIVGARNADAAREATRGIA------GVEIAAL 81

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DLA  AS+  F ARF      + +++N+AGVM  P+    DG E Q+ V           
Sbjct: 82  DLADLASVAAFAARFVEARRDVDIVINSAGVMACPETRVGDGLEAQMAVNHLGHYALVNG 141

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRR 203
                               H+   I   D   +  YD   AY QSK AN LFA +L   
Sbjct: 142 LWPVLAQGDGARVVAVSSLGHRLSPIRWDDAQFAHGYDKWLAYGQSKTANALFAVQLDAL 201

Query: 204 LLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFI----YPLFWPFMKKPEIGGQTVVHA 259
               GV   ++ PG + T + RH++  + + + ++     P+  P  K P  G  T V A
Sbjct: 202 GAPYGVRAYSLHPGKIATPLQRHLTREEMMAQGWVDEHGLPID-PTFKTPAQGAATQVWA 260

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQ---------EAQDFELAQWLWRVSEAWTKLD 305
           A  P+L    G Y  D   A  +Q          A D E A  LW  S A T +D
Sbjct: 261 ATSPRLAGIGGVYCEDCDIAVVTQGNEESGVRPHAIDPEEAARLWAWSAALTGID 315


>UniRef50_Q17GA5 Cluster: Short-chain dehydrogenase; n=1; Aedes
           aegypti|Rep: Short-chain dehydrogenase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 252

 Score =  105 bits (251), Expect = 2e-21
 Identities = 72/250 (28%), Positives = 114/250 (45%), Gaps = 11/250 (4%)

Query: 68  DIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKG-VTKDGF 126
           +IV E+NN+ +  R  D++S AS+R F       E  + VL++NAGV +  K  VT DG 
Sbjct: 8   EIVAESNNQNIVIRHVDMSSLASVRNFAKEILSTESVIDVLIHNAGVAQGLKSKVTSDGL 67

Query: 127 ETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLN----MSENYDA 182
              L                  K              ++   + K+DL+    ++  Y A
Sbjct: 68  VFSLATNYYGPFLLTHLLINMLKKSDQGRIIVVSSKLYRYAHV-KRDLSNINPINSQYSA 126

Query: 183 -SAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPL 241
            +  Y+ SK   ++F +EL RRL GT V    + PG++DT I R++    ++      P+
Sbjct: 127 PTQLYNLSKFMEIMFTQELARRLRGTRVTANCLHPGVIDTGIWRNIPFPLNIV---FKPI 183

Query: 242 FWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAW 301
            W F + PE G +T V+  + P++   +G Y+   K  E +Q  QD EL   LW  S   
Sbjct: 184 QWCF-RTPEEGARTTVYLTVTPEVDKISGKYFRGCKVTEINQRVQDVELQGKLWEASRTL 242

Query: 302 TKLDEHKQAI 311
            +L +    I
Sbjct: 243 VQLTDEDPMI 252


>UniRef50_A4CX59 Cluster: Short-chain dehydrogenase/reductase (SDR)
           superfamily protein; n=7; Bacteria|Rep: Short-chain
           dehydrogenase/reductase (SDR) superfamily protein -
           Synechococcus sp. (strain WH7805)
          Length = 306

 Score =  103 bits (248), Expect = 5e-21
 Identities = 83/298 (27%), Positives = 125/298 (41%), Gaps = 17/298 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R  ++TGANSG+G    +    RG  V M CR  +K E  R  ++LE     +     DL
Sbjct: 14  RVALVTGANSGLGLETTRALIGRGCTVLMGCRSARKGEAARA-LLLEAGGSGLDLFELDL 72

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           +   S+             L +L+NNAG+M PP+ +++ G E Q  V             
Sbjct: 73  SDLTSVARCARDVADRYGRLDLLINNAGLMAPPRMLSQQGHEMQFAVNHLGHFALTQALL 132

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL- 204
                                G +   DL   + YD   AYSQSKLAN++FA EL +RL 
Sbjct: 133 PLMNNRPQARVVTVTSGAQYFGAMAWDDLQGEQRYDRWKAYSQSKLANVMFALELNQRLQ 192

Query: 205 -LGTGVATIAVDPGLVDTDITR-HMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
             G+ V ++A  PGL  T++    ++   +      Y L  P  +    G    ++AA  
Sbjct: 193 ASGSAVRSLAAHPGLARTNLQPVSVAATGAWQEALAYRLMDPLFQSAAQGALPQLYAATA 252

Query: 263 PKLKDCAGDYY----VDMKKAEPSQE-----AQDFELAQWLWRVSEAWTKLDEHKQAI 311
                  G++Y    +   +  P Q+     A+D    Q LW VSE+ T  + H  A+
Sbjct: 253 SAAG--GGEHYGPGQLGGMRGAPKQQPVARAAKDQHQRQRLWTVSESLT--EHHSAAV 306


>UniRef50_Q1QSD6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Chromohalobacter salexigens DSM 3043|Rep:
           Short-chain dehydrogenase/reductase SDR -
           Chromohalobacter salexigens (strain DSM 3043 / ATCC
           BAA-138 / NCIMB13768)
          Length = 306

 Score =  103 bits (247), Expect = 6e-21
 Identities = 78/248 (31%), Positives = 110/248 (44%), Gaps = 7/248 (2%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAST 88
           ++TGA +G+G   AK  A  G +V +A R+  K       I        V     DL S 
Sbjct: 13  VVTGATAGLGLETAKGLAAHGYRVIVAARNADKGALACHAIRTHVPRATVRHEALDLDSL 72

Query: 89  ASIREFVARFKGEEPHLHVLVNNAGVMEPPK-GVTKDGFETQLGVXXXXXXXXXXXXXXX 147
           AS+R+F AR   +E  L  L+NNAG+M  P+   T+DGFE Q GV               
Sbjct: 73  ASVRDFAARLNQDESSLARLINNAGIMALPRLERTRDGFERQWGVNFLGHFLLTSELLPL 132

Query: 148 XKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRR--LL 205
                           H+ GRI   D N   NYD   AY QSKLA LLFA+ L ++    
Sbjct: 133 LAAAASPRVVQLSSLAHRGGRIAFDDPNGEANYDPWQAYRQSKLAMLLFAQALQKQSDAR 192

Query: 206 GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEI-GGQTVVHAALDPK 264
             G+ ++A  PGL  T +       + +    ++ L  P + +    G + ++HAAL   
Sbjct: 193 QWGLVSLAAHPGLSRTALFDDGVRSRPIVG-SVFKLALPLISQSAAEGARPILHAALSDT 251

Query: 265 LKDCAGDY 272
           +    GDY
Sbjct: 252 VG--PGDY 257


>UniRef50_UPI0000587008 Cluster: PREDICTED: hypothetical protein;
           n=2; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 377

 Score =  103 bits (246), Expect = 8e-21
 Identities = 85/296 (28%), Positives = 124/296 (41%), Gaps = 23/296 (7%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + +IITGAN+GIG  AA+  AK   +V MACR   K  +   ++  +     V     DL
Sbjct: 70  KVVIITGANTGIGLVAAEMLAKDDYEVIMACRSEDKANQAVSEVQKKVPGAKVSFMKLDL 129

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGV----MEPPKGVTKDGFETQLGVXXXXXXXXX 141
            S  S+R+F   +   E  LHVL NNAG+        +  T+DGFE   GV         
Sbjct: 130 NSLKSVRDFSDAYHATEKPLHVLCNNAGLTTGFSTKDRLETEDGFEMTFGVNHLGHFLLT 189

Query: 142 XXXXXXXKXXXXX----XXXXXXXXXH-------QRGRIHKQD-----LNMSENYDASAA 185
                  K                  H        RGR    D     ++  + +D   A
Sbjct: 190 HLLLDVMKKTAETCDEVRIVNTSSMLHDPEGPGGNRGRAAHLDFDNLMMDKPDTFDGMLA 249

Query: 186 YSQSKLANLLFARELGRRLLGTGVATIAVDPGLVD-TDITRHMSMMKSVTRFFIYPL--F 242
           Y  SKLAN  F+ EL +RL G+ + +  + PG +  T + R+ +    +    I PL   
Sbjct: 250 YRNSKLANCAFSVELAKRLKGSKITSNTLCPGFIPATGLGRNETQWAKIRMAVITPLLKL 309

Query: 243 WPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
               +  E GG  V +    P  K   G +  D K  + S E++D E+ + LW +S
Sbjct: 310 IGITRTVEHGGGMVHYVVTSPDWKGLTGKHSTDFKITDSSTESRDPEVGKKLWDMS 365


>UniRef50_Q64PT9 Cluster: Putative oxidoreductase; n=7;
           Bacteroidales|Rep: Putative oxidoreductase - Bacteroides
           fragilis
          Length = 290

 Score =  103 bits (246), Expect = 8e-21
 Identities = 73/246 (29%), Positives = 109/246 (44%), Gaps = 9/246 (3%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + +  +ITGA+ G+G    +  A  G  V MAC    K E + R++V ET N+ +     
Sbjct: 3   ERKLAVITGADGGMGTEITRAVACAGYDVIMACYSSSKAETKCRELVKETGNEKIEVWQI 62

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DLAS AS+R F  R   ++  + +L+NNAG ME    +T+DG E  + V           
Sbjct: 63  DLASLASVRAFADRMLRQKTPVALLMNNAGTMETGLHITEDGLERTVSVNYVGPYLLTRL 122

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDL---NMSENYDASAAYSQSKLANLLFAREL 200
                               +  G++   D        ++     YS +KLA LLF  EL
Sbjct: 123 LLPL--MGEGTRIVNMVSCTYAIGKLDFPDFFLRGRKGSFWRIPIYSNTKLALLLFTIEL 180

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAA 260
             RL   G+   A DPG+V T+I R       +T  F    F PF++ P  G  T +   
Sbjct: 181 AERLRARGITVNAADPGIVSTNIIRMDQWFDPLTDIF----FRPFIRTPLQGAATAIGLL 236

Query: 261 LDPKLK 266
           LD +++
Sbjct: 237 LDAEVE 242


>UniRef50_Q8RWK2 Cluster: Ribitol dehydrogenase-like; n=13;
           Magnoliophyta|Rep: Ribitol dehydrogenase-like -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 339

 Score =  102 bits (245), Expect = 1e-20
 Identities = 83/285 (29%), Positives = 123/285 (43%), Gaps = 14/285 (4%)

Query: 27  TIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLA 86
           T IITG  SGIG   A+  AKRG +V MA RD+KK E  +  I+ E     +     DL+
Sbjct: 38  TAIITGGTSGIGAETARVLAKRGVRVVMAVRDMKKAEMVKERIIRENPEADIILFEIDLS 97

Query: 87  STASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQ-----LGVXXXXXXXXX 141
           S +S+  F ++F  ++  L++L+NNAGV  P    +++  E       LG          
Sbjct: 98  SLSSVARFCSQFLSQDLPLNILINNAGVFSPNLEFSEEKIELTFATNFLGHYLLTEMLIE 157

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGR----IHKQDLNMSENYDASAAYSQSKLANLLFA 197
                  K              H   +       + L+    Y+ + AY+QSKLA +L A
Sbjct: 158 KMIDTAEKSGIEGRIINLSSVIHNWVKPDCFSFPKLLHPISRYNGTRAYAQSKLATILHA 217

Query: 198 RELGRRL--LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQT 255
           + L ++L      V   AV PG+V T I R    + + + F I       +K    G  T
Sbjct: 218 KALSKQLKDRNANVTINAVHPGIVKTGIIRAHKGLFTDSLFLIAS---KLLKSISQGAAT 274

Query: 256 VVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEA 300
             + AL  + K  +G Y+ D  +   S  A D  +A  L   S A
Sbjct: 275 TCYVALSNETKGLSGKYFADCNETNCSDLANDEYVALKLCTQSRA 319


>UniRef50_O74959 Cluster: Short chain dehydrogenase; n=1;
           Schizosaccharomyces pombe|Rep: Short chain dehydrogenase
           - Schizosaccharomyces pombe (Fission yeast)
          Length = 339

 Score =  102 bits (244), Expect = 1e-20
 Identities = 72/283 (25%), Positives = 127/283 (44%), Gaps = 14/283 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +  ++TG++ GIG   A + A++GAKV++A R+ +K ++  + I  E  +  +     DL
Sbjct: 43  KVALVTGSSGGIGYVTALELARKGAKVYLAGRNEEKYQKVMKQIHDEVRHSKIRFLRLDL 102

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
               S+ +    F  +E  LH+LVNNAG+M PP  +TKDG+E Q+               
Sbjct: 103 LDFESVYQAAESFIAKEEKLHILVNNAGIMNPPFELTKDGYELQIQTNYLSHYLFTELLL 162

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQ---------DLNMSE-NYDASAAYSQSKLANLL 195
              +              H     + Q         DLN+        A Y QSK A +L
Sbjct: 163 PTLRRTAEECRPGDVRIVHVASIAYLQAPYSGIYFPDLNLPHVLLGTFARYGQSKYAQIL 222

Query: 196 FARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQT 255
           ++  L +RL   G+ ++++ PG++ T++TR+        +     +F   +  P  G  T
Sbjct: 223 YSIALAKRLEKYGIYSVSLHPGVIRTELTRYSPTF--ALKLLEKSVFQYLLLDPIRGAMT 280

Query: 256 VVHAALDPKL--KDCAGDYYVDMKKAEPSQEAQDFELAQWLWR 296
            ++AA  P++  +   G Y+  + +      A D    + L+R
Sbjct: 281 SLYAATSPEISKEHLNGAYFTAIAQRGILHRAHDDAFVEELYR 323


>UniRef50_A4RS19 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 292

 Score =  101 bits (243), Expect = 2e-20
 Identities = 78/261 (29%), Positives = 116/261 (44%), Gaps = 19/261 (7%)

Query: 28  IIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAS 87
           ++ITGAN+G+G   AK  AK G +V  A RD  + E  +  ++       V     DLA 
Sbjct: 3   VVITGANTGLGYETAKAAAKAGRRVVAAVRDEARGERAKTRVLAAVPEAKVDVMLVDLAD 62

Query: 88  TASIREFVARFKGEEPHLHVLVNNAGVMEPP-KGVTKDGFETQLGV--XXXXXXXXXXXX 144
             S+R F   F+ +   L  LVNN+GVM PP +  TKDG E Q+ V              
Sbjct: 63  FESVRAFARAFEAKYDRLDALVNNSGVMAPPSRSETKDGNELQMQVNHLGHFLLTSLLLD 122

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYD----ASAAYSQSKLANLLFAREL 200
                              H  G +   ++N    +       A Y ++K+AN++F  EL
Sbjct: 123 TMVNTPSDDKRIVNLSSIAHNFGTLDFHNVNSEGVFGYPFLGWATYGRTKMANIMFTFEL 182

Query: 201 GRRLLGTGVATIAVD---PGLVDTDITRHMSMMKSVTRFFIYPLFWPFMK--KPEIGGQT 255
            RRL   GV  +AV+   PG+VDT++ R +S+         YP      K   PE G + 
Sbjct: 183 DRRLKAKGVTNVAVNAVHPGVVDTELNRSLSL-------DFYPQLKAAGKLITPEQGARG 235

Query: 256 VVHAALDPKLKDCAGDYYVDM 276
            +  A+D K +  +G Y  ++
Sbjct: 236 QIALAMDEKYRGVSGVYVSEL 256


>UniRef50_Q0AP26 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Maricaulis maris (strain MCS10)
          Length = 325

 Score =  101 bits (242), Expect = 2e-20
 Identities = 84/295 (28%), Positives = 115/295 (38%), Gaps = 25/295 (8%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +T I+TG  SGIG    +  A RG  V +  R   K  E    I  + +       P DL
Sbjct: 31  KTAIVTGGYSGIGLETVRSLAARGVSVIVPVRSPDKAAEALAGITGDVSTA-----PMDL 85

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A  AS+R F     G    L +L+NNAG+M  P+     G+E+Q G+             
Sbjct: 86  ADLASVRGFADSVSGRLARLDLLINNAGIMACPEARVGPGWESQFGINHMGHFALTLSLL 145

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-YDASAAYSQSKLANLLFARELGRRL 204
              K              H+   I   D+   +  YD   AY Q+K AN LFA  L RRL
Sbjct: 146 PLLKKTAGARVVALSSTAHKLSDIRWDDIQYRDTPYDKWQAYGQAKTANALFANGLSRRL 205

Query: 205 LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFI------YPLFWPFMKKPEIGGQTVVH 258
              G    +V PG + T + RH+   + +   ++        L     K PE G  T + 
Sbjct: 206 QDNGGLAFSVHPGGIFTPLQRHLPQEEMIALGWLGEDGEPSELARQGFKTPEQGCSTTLW 265

Query: 259 AALDPKLKDCAGDYYVDMKKAEPSQEAQDF-------------ELAQWLWRVSEA 300
           AA    L    G Y  +   A P+  +                E A+ LW VSEA
Sbjct: 266 AATAADLAGKPGVYCENADIAAPTDPSSPMARYGGVDAHACSDESAERLWAVSEA 320


>UniRef50_A1G986 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Salinispora|Rep: Short-chain
           dehydrogenase/reductase SDR - Salinispora arenicola
           CNS205
          Length = 334

 Score =  101 bits (242), Expect = 2e-20
 Identities = 65/204 (31%), Positives = 90/204 (44%), Gaps = 3/204 (1%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RT ++TGAN G+G   AK FA RGA V MA R+  K  +   +I  ET    +     DL
Sbjct: 43  RTAVVTGANGGLGLETAKVFASRGAHVVMAVRNQDKATKAVAEIRAETPTASLELVELDL 102

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
            S AS+R+   +       + +LVNNAG+M  P+  T DG+E Q GV             
Sbjct: 103 GSQASVRQAAEQILARHGQIDILVNNAGLMALPERRTTDGYEMQFGVNHLGHWTLTALLM 162

Query: 146 XXXKXXXXXXXXXXXXXXHQRGR-IHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
                             H  GR +   + +++  Y    AY QSKLAN  FA  L +  
Sbjct: 163 PALLAAPAARVVTVTSTAHHFGRSVDPDNPHLNGAYGPWRAYGQSKLANYHFALGLQQEF 222

Query: 205 --LGTGVATIAVDPGLVDTDITRH 226
              G    ++   PGL  +D+  H
Sbjct: 223 DRAGVNAQSLIAHPGLTSSDLQVH 246


>UniRef50_Q9FQM0 Cluster: Forever young oxidoreductase; n=20;
           Magnoliophyta|Rep: Forever young oxidoreductase -
           Arabidopsis thaliana (Mouse-ear cress)
          Length = 376

 Score =  101 bits (242), Expect = 2e-20
 Identities = 80/294 (27%), Positives = 136/294 (46%), Gaps = 33/294 (11%)

Query: 27  TIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKY--------V 78
           T ++TG+ SGIG+  A+  A+ GA V MA R+ K  +E    ++L+  N++        +
Sbjct: 59  TCVVTGSTSGIGRETARQLAEAGAHVVMAVRNTKAAQE----LILQWQNEWSGKGLPLNI 114

Query: 79  YCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGV--MEPPKGVTKDGFETQLGVXXXX 136
                DL S  S+  F   F      LHVL+NNAG+  M   +  +++G+E  + V    
Sbjct: 115 EAMEIDLLSLDSVARFAEAFNARLGPLHVLINNAGMFAMGEAQKFSEEGYEQHMQVNHLA 174

Query: 137 XXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNM---SENYDASAAYSQSKLAN 193
                                      H  G +   D+N+      Y +   YS SKLA 
Sbjct: 175 PALLSVLLLPSLIRGSPSRIINVNSVMHSVGFVDPDDMNVVSGRRKYSSLIGYSSSKLAQ 234

Query: 194 LLFARELGRRL-LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIG 252
           ++F+  L ++L L TGV+ + + PG+V T++ R +S +       +Y +   F+  P+ G
Sbjct: 235 IMFSSILFKKLPLETGVSVVCLSPGVVLTNVARDLSRILQA----LYAVIPYFIFSPQEG 290

Query: 253 GQTVVHAALDPKLKDC-----AGDYYV------DMKKAEPSQEAQDFELAQWLW 295
            ++ + +A DP++ +        D+ V      D + A PS+EA + E AQ +W
Sbjct: 291 CRSSLFSATDPQIPEYWETLKNDDWPVCPFISQDCRPANPSEEAHNTETAQRVW 344


>UniRef50_UPI0000E235EA Cluster: PREDICTED: similar to MGC81751
           protein isoform 1; n=1; Pan troglodytes|Rep: PREDICTED:
           similar to MGC81751 protein isoform 1 - Pan troglodytes
          Length = 340

 Score =  101 bits (241), Expect = 3e-20
 Identities = 48/112 (42%), Positives = 70/112 (62%), Gaps = 1/112 (0%)

Query: 16  PYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNN 75
           P+D  V+   R  ++TG NSGIGKA A + AKRG  V + CRD  + E+ R +I+ E++N
Sbjct: 31  PHDLEVQVPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQARAEDARDEIIRESSN 90

Query: 76  KYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFE 127
           + ++    DL+    I +FV  FK +E  LHVL+NNAG M   + +T+DG E
Sbjct: 91  QNIFLHIVDLSDPKQIWKFVENFK-QEHKLHVLINNAGCMVNKRELTEDGLE 141


>UniRef50_Q4UJ93 Cluster: Dehydrogenase/reductase (SDR family)
           X-linked; n=6; Eutheria|Rep: Dehydrogenase/reductase
           (SDR family) X-linked - Homo sapiens (Human)
          Length = 245

 Score =  101 bits (241), Expect = 3e-20
 Identities = 73/209 (34%), Positives = 99/209 (47%), Gaps = 29/209 (13%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           +R  I+TG   GIG + AK  A+ G  V                I++E    ++YC   D
Sbjct: 43  DRVAIVTGGTDGIGYSTAKHLARLGMHV----------------IIVE----FLYC---D 79

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           LAS  SIR+FV +FK ++  LHVL+NNAGVM  P+  T+DGFE   G+            
Sbjct: 80  LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLL 139

Query: 145 XXXXKXX----XXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAREL 200
               K                  H    ++  DL  S  Y   AAY+QSKLA +LF   L
Sbjct: 140 LDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFTYHL 199

Query: 201 GRRLL--GTGVATIAVDPGLVDTDITRHM 227
            R L   G+ V    VDPG+V+TD+ +H+
Sbjct: 200 QRLLAAEGSHVTANVVDPGVVNTDVYKHV 228


>UniRef50_A0YA00 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family protein; n=1; marine
           gamma proteobacterium HTCC2143|Rep: Oxidoreductase,
           short-chain dehydrogenase/reductase family protein -
           marine gamma proteobacterium HTCC2143
          Length = 323

 Score =  100 bits (240), Expect = 4e-20
 Identities = 87/294 (29%), Positives = 116/294 (39%), Gaps = 14/294 (4%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYC 80
           +   N+  I+TG  SGIG       A  GA V +A RD+ + E    ++  +     V  
Sbjct: 19  INLSNKNAIVTGGYSGIGIETVVALATAGANVTIAGRDLSRAERTADELNSKGLLGVVDA 78

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXX 140
              DL S  S++ FV  +      L +LVNNAGVM  P   T DGFE Q G         
Sbjct: 79  MSLDLGSLQSVKGFVESYCASHASLEILVNNAGVMACPFETTTDGFELQFGTNHIGHYAL 138

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE-NYDASAAYSQSKLANLLFARE 199
                                  H    +   D+N S+  YDA ++Y Q+K AN L A  
Sbjct: 139 SRLLLPLLLNAESARVVCLSSTGHMISPVIFDDINFSQRKYDAWSSYGQAKTANSLTAVA 198

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFI--YPLFWPFMKKPEIGGQTVV 257
           L +     GV   AV PG + T + RHM       R ++          K  E G  T  
Sbjct: 199 LQQLYGSKGVDAFAVHPGGIMTSLQRHMEQKDIEARGWVDAEGNINERFKTVEQGASTST 258

Query: 258 HAALDPKLKDCAGDYYVDMKKAE-----PSQE------AQDFELAQWLWRVSEA 300
            AA   +L    G Y  D   AE     P         A D E A+ LW++SE+
Sbjct: 259 WAATASELTAKGGVYLEDCDFAEVVASRPDYPKGVIAYAVDSEAARQLWQISES 312


>UniRef50_A6G6M7 Cluster: Possible dehydrogenase; n=1; Plesiocystis
           pacifica SIR-1|Rep: Possible dehydrogenase -
           Plesiocystis pacifica SIR-1
          Length = 320

 Score =  100 bits (239), Expect = 6e-20
 Identities = 86/283 (30%), Positives = 115/283 (40%), Gaps = 14/283 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +  ++TG+NSG+G    +    RGA V    R   K E   RD         + C   + 
Sbjct: 37  KVYLLTGSNSGLGLETLRVLNLRGATVIATARTQAKAEGALRDAGASERGVAMACELSEP 96

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           +S  +  E V  + GE+  L  ++ NAG+M  PK   K G+E Q                
Sbjct: 97  SSVRACVEAVNAWCGEQRPLAGIIANAGIMALPKLQLKFGYELQF--FTNHIGHFMLVNG 154

Query: 146 XXXKXXXXXXXXXXXXXXHQRGR----IHKQDLNMSENYDASAAYSQSKLANLLFARELG 201
                             HQ       I   +L+  + Y   A Y QSKLANLLFAREL 
Sbjct: 155 VLDSLAPDGRVVMLASSAHQGAPRAEGIQFDNLDGRKGYAPWANYGQSKLANLLFARELD 214

Query: 202 RRLLGT---GVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVH 258
           RRL  +     +  AV PG++ T + RH+S     T F    L  PF+K    G  T   
Sbjct: 215 RRLAASEHPQRSANAVHPGVIPTPLGRHVS---KATWFTFSVLGKPFLKTVHEGAATQCF 271

Query: 259 AALDPKL--KDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
            A    +      G Y+ D   AE S    D  LA  LW+VSE
Sbjct: 272 VATHASVGGGGLRGQYFADSNVAESSAHGSDMALAAKLWQVSE 314


>UniRef50_Q5CMZ5 Cluster: ENSANGP00000010899; n=2;
           Cryptosporidium|Rep: ENSANGP00000010899 -
           Cryptosporidium hominis
          Length = 380

 Score =  100 bits (239), Expect = 6e-20
 Identities = 72/280 (25%), Positives = 116/280 (41%), Gaps = 9/280 (3%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIV-LETNNKYVYCRPC 83
           +T++ITG + GIG    K  A  G +++   CRD+   E  +  +  +      ++   C
Sbjct: 92  KTVVITGCSRGIGLETVKQLASWGVSELIFCCRDIAAMENVKNQLTSIRLPPNKIHSIEC 151

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPP----KGVTKDGFETQLGVXXXXXXX 139
           DL+S  S+     +       + +L+NNAG+M PP     GV K      LG        
Sbjct: 152 DLSSLHSVELCSRKILSTVDKIDILINNAGIMAPPFQLINGVEKQFMTNYLG--HYHLTT 209

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                    K                   I + +    ++Y+    Y  SKL N+ F RE
Sbjct: 210 NLIPLLQRSKCRIINVSSIAHLAVPFGFNISEIENINEKSYNKMRFYGISKLCNIYFTRE 269

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
           L +R    G+  +++ PG VDTD+ R++    S+    +YPL   F K    G QT ++ 
Sbjct: 270 LQKRFGSAGLTAVSLHPGCVDTDLGRYV-RENSIAFALLYPLMKLFSKTSFSGAQTTLYC 328

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
              P++K   G YY        S  + D + +  LW  S+
Sbjct: 329 CAIPEIKLAPGGYYSQCTLDISSPASLDEDASAQLWDYSK 368


>UniRef50_UPI000058941E Cluster: PREDICTED: hypothetical protein;
           n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
           hypothetical protein - Strongylocentrotus purpuratus
          Length = 356

 Score =   99 bits (238), Expect = 7e-20
 Identities = 83/300 (27%), Positives = 125/300 (41%), Gaps = 16/300 (5%)

Query: 16  PYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNN 75
           P D S R D +  I+TG  SGIG   AK F ++G +V +     +  ++  + I  E   
Sbjct: 32  PEDIS-RHDGKVAIVTGGASGIGLETAKAFCRKGIQVIIGSPHAENAKKAIQVIKKENAL 90

Query: 76  KYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGV--- 132
             V   P DL+S  S+R+F   F   +  LH++VNNAGVM  P   T D FE Q  V   
Sbjct: 91  ARVEWIPLDLSSLQSVRDFAETFLNSKLPLHIIVNNAGVMMTPYHKTADDFELQFQVNYL 150

Query: 133 -XXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRI---HKQDLNMSENYDASAAYSQ 188
                                           H  G +   H   +   + Y    AY+ 
Sbjct: 151 GHYLLMRLLLDKLHNSAHSRSYAKIINVSSIAHFGGWMDASHLPKIMPKKEYSPYKAYAD 210

Query: 189 SKLANLLFARELGRRLLGTG--VATIAVDPGLVDTDITRHMSMMKSVTRFFI--YPLFWP 244
           SKLA +L  +EL RR+      V   ++ PG+V + + ++M  +  + +  +    L W 
Sbjct: 211 SKLAVVLGTQELQRRIYRASRRVTVNSLHPGVVGSQLYQNMHPLIQMAKIVVSQLGLIWT 270

Query: 245 FMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
             K    G  T ++AAL  +++   G Y  +      S    D +L   LW+ S  W KL
Sbjct: 271 IEK----GSATTIYAALSDEMEGVGGCYLDNCGSIASSSLTYDRKLQVALWKESCEWCKL 326


>UniRef50_Q5FS41 Cluster: Putative oxidoreductase; n=1;
           Gluconobacter oxydans|Rep: Putative oxidoreductase -
           Gluconobacter oxydans (Gluconobacter suboxydans)
          Length = 323

 Score =   99 bits (238), Expect = 7e-20
 Identities = 92/310 (29%), Positives = 126/310 (40%), Gaps = 30/310 (9%)

Query: 18  DRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKY 77
           D   R D +T +ITG+  G+G   A   AK+GA + ++ R+  K   Q     L     +
Sbjct: 12  DSLERLDGKTALITGSTGGLGFEVACGLAKQGAAILLSGRNHNK--GQAALARLHERVPF 69

Query: 78  VYCR--PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVT-KDGFETQLGVXX 134
           V  R    DLAS A I  F +  +     +H+L NNAGVM P   +T KDGFE Q G   
Sbjct: 70  VKARFELLDLASLAGIEAFASAMRSRGEPIHLLANNAGVMGPATRLTTKDGFELQFGTNH 129

Query: 135 XXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANL 194
                                          +G I   DLN   +Y+    Y QSKL NL
Sbjct: 130 LGHFALTGRLLPLLAAGNATVMTVASLAA-LKGEIPFGDLNARHSYNPMVRYRQSKLCNL 188

Query: 195 LFARELGRRLL-------------GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPL 241
           LFA EL RR L             G   + I  + G +D    +    M+ + R    P+
Sbjct: 189 LFALELNRRALKAPWPIHSRAAHPGWAASDIVANNGSLDQSANKAARFMRGLARRVAGPV 248

Query: 242 FWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDM----KKAEPS-----QEAQDFELAQ 292
           F    +  E G   +++A   P+ +D  G YY       ++  P        A   ELA+
Sbjct: 249 FHAMGQTVEEGAWPLLYALASPEARD--GGYYGPQGPGERRGVPGIAGLPALAHVPELAE 306

Query: 293 WLWRVSEAWT 302
            LW VSE  T
Sbjct: 307 RLWTVSEQMT 316


>UniRef50_UPI0000E475C8 Cluster: PREDICTED: similar to Retinol
           dehydrogenase 11 (all-trans/9-cis/11-cis); n=5;
           Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
           Retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -
           Strongylocentrotus purpuratus
          Length = 303

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 82/290 (28%), Positives = 124/290 (42%), Gaps = 14/290 (4%)

Query: 13  SGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACR-DVKKCEEQRRDIVL 71
           S  P    V    + II+TGAN+GIG   AK  A+ GAKV +ACR + K    +  D+V 
Sbjct: 6   SSQPDLPEVDLKGKVIIVTGANAGIGYETAKSLAQMGAKVILACRSETKALGVEELDLV- 64

Query: 72  ETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLG 131
                Y+     DL S AS   F   FK     LH LV NAG+   P   + DG E    
Sbjct: 65  -----YM---NLDLGSLASTTNFAESFKARGLPLHALVCNAGMAFGPDEPSVDGLEIHFQ 116

Query: 132 VXXXXXXXXXXXXXXXXKXXX-XXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSK 190
           V                K               ++  R +++D+    N + +  YS +K
Sbjct: 117 VNYLSHFLLILQLLPVLKSSGPNSRVVLVASLAYRFARWNEEDI-QGTNENKTTIYSNTK 175

Query: 191 LANLLFARELGRRLLGTGVATIAVDPGLVDTD-ITRHMSMMKSVTRFFI-YPLFWPFMKK 248
           L  ++    L RRL G+G+   +V PG+V+T+ + R    +  +T  F    +   F++ 
Sbjct: 176 LYQIMQMLALERRLEGSGIGIFSVHPGIVETELVKREGQRIPMMTSLFARLGMSTHFLRN 235

Query: 249 PEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           P  G  T +HAA +P        Y+ + K    +   +D    + LW+ S
Sbjct: 236 PFKGALTTLHAAANPTYDGKTALYFENSKPHSLTSLPRDRWKQEHLWKYS 285


>UniRef50_UPI0000DB7DE5 Cluster: PREDICTED: similar to retinol
           dehydrogenase 11, partial; n=1; Apis mellifera|Rep:
           PREDICTED: similar to retinol dehydrogenase 11, partial
           - Apis mellifera
          Length = 205

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 62/194 (31%), Positives = 90/194 (46%), Gaps = 4/194 (2%)

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           +L S A+I++        E ++H+L+NNAGV   P   TKDGFET   V           
Sbjct: 11  NLNSFANIKKCAQHLLTTESNIHILINNAGVFLHPFEKTKDGFETHFQVNYLGHFLLTLL 70

Query: 144 XXXXXKXXXXX-XXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR 202
                +               H+ G I+ +DLN+   Y     Y QSKLAN+LF +EL  
Sbjct: 71  LLPKIEESGPGCRIINVSSLAHKYGDINFEDLNLEHCYTPIKGYCQSKLANILFTKELNN 130

Query: 203 RLLGTGVATI---AVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
           +L   G+  I   ++ PG+V T+I R++          I  L  P MK P+ G QT ++ 
Sbjct: 131 KLRAAGIQNINVYSLHPGIVKTEIARYLDASYFRGARLISSLINPLMKTPDQGAQTTIYC 190

Query: 260 ALDPKLKDCAGDYY 273
           A+D      +G YY
Sbjct: 191 AIDENAGKESGLYY 204


>UniRef50_Q9RTQ6 Cluster: Daunorubicin C-13 ketoreductase; n=2;
           Deinococcus|Rep: Daunorubicin C-13 ketoreductase -
           Deinococcus radiodurans
          Length = 400

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 83/285 (29%), Positives = 119/285 (41%), Gaps = 22/285 (7%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R I+ITGA  GIG   A++ A RGA+V +  RD  +       +  E           DL
Sbjct: 132 RRILITGATGGIGLETARELAGRGAQVVIVGRDPGRTAR----VAAEVGAAGTLL--ADL 185

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFE-----TQLGVXXXXXXXX 140
           +    +    A ++     L VLVNNAG +   +  +++G E       L          
Sbjct: 186 SELVQVERAAAEYRERFGELDVLVNNAGALHRERQESREGIELTWALNHLAPFLLTRELL 245

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAREL 200
                                  H  GRI   D      Y A  AY+QSKLAN+LFAREL
Sbjct: 246 PLLRRSSETRRVPARVVTVASAAHVVGRIRFDDPEFRRGYAAWPAYAQSKLANILFAREL 305

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFF-IYPLFWPFMKKPEIGGQTVVHA 259
            RR     V ++++ PG+V +   ++        RF   Y L   F   PE G QT +HA
Sbjct: 306 ARR--EPSVLSVSLHPGMVASGFGKN-----GGGRFAQAYGLLDRFSLTPEQGAQTSLHA 358

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
              P      G YY + ++  P+ +A D   A  LW +SE + ++
Sbjct: 359 VSAPV---HTGGYYANARRVTPAPQALDDGAAARLWALSEGYLQV 400


>UniRef50_A0PJE2 Cluster: DHRS12 protein; n=23; Eumetazoa|Rep:
           DHRS12 protein - Homo sapiens (Human)
          Length = 312

 Score = 99.1 bits (236), Expect = 1e-19
 Identities = 48/112 (42%), Positives = 68/112 (60%), Gaps = 1/112 (0%)

Query: 16  PYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNN 75
           P+D  V+   R  ++TG NSGIGKA A + AKRG  V + CRD    E+ R +I+ E+ N
Sbjct: 26  PHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGN 85

Query: 76  KYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFE 127
           + ++    DL+    I +FV  FK +E  LHVL+NNAG M   + +T+DG E
Sbjct: 86  QNIFLHIVDLSDPKQIWKFVENFK-QEHKLHVLINNAGCMVNKRELTEDGLE 136


>UniRef50_A3CUN1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Methanoculleus marisnigri JR1|Rep: Short-chain
           dehydrogenase/reductase SDR - Methanoculleus marisnigri
           (strain ATCC 35101 / DSM 1498 / JR1)
          Length = 281

 Score = 98.7 bits (235), Expect = 2e-19
 Identities = 71/278 (25%), Positives = 115/278 (41%), Gaps = 13/278 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +TI++TG+  GIGK  A+  +++G +V +  RD  K      ++   T +  +     DL
Sbjct: 3   QTILVTGSTDGIGKVTARALSRQGHRVLLHGRDPGKGRRVLAELEAATGSDRLDLFIADL 62

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           +    +R+      G    L VL+NNAGV  P + V   G ET   V             
Sbjct: 63  SVQERVRDLAEEIAGAYDRLDVLINNAGVFMPEREVAPGGIETTFAVNFLAQFLLAHEFL 122

Query: 146 XXXKXXXXXXXXXXXXXXHQRGR-IHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
                             H+  R I  ++L    +YDA  AY+ SK+  + F   L R L
Sbjct: 123 PLLARSAPARIVNVASIAHRSVRSIDWENLPGFPDYDAYDAYAVSKVGVVAFTARLAREL 182

Query: 205 LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPK 264
            GTGV   ++ PG+++T + R  +  +                 P+ G +  VH AL P 
Sbjct: 183 EGTGVTANSLHPGVIETKLLRAYTHGRDGG------------APPKKGAEAEVHLALSPD 230

Query: 265 LKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWT 302
               +G Y+ + +   PS  A D  + +  W +  + T
Sbjct: 231 AGKTSGGYFEESRWTRPSSLALDPVIQERFWEMGSSLT 268


>UniRef50_UPI0000D9F6C2 Cluster: PREDICTED: similar to
           dehydrogenase/reductase (SDR family) X-linked; n=1;
           Macaca mulatta|Rep: PREDICTED: similar to
           dehydrogenase/reductase (SDR family) X-linked - Macaca
           mulatta
          Length = 439

 Score = 98.3 bits (234), Expect = 2e-19
 Identities = 65/176 (36%), Positives = 83/176 (47%), Gaps = 9/176 (5%)

Query: 83  CDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX 142
           CDLAS  SIR+FV +FK ++  LHVLVNNAGVM  P+  T+DGFE   G+          
Sbjct: 28  CDLASMMSIRDFVQKFKMKKIPLHVLVNNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTN 87

Query: 143 XXXXXXKXX----XXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAR 198
                 +                  H    ++  DL  S  Y A AAY+QSKLA +LF  
Sbjct: 88  LLLDTLRESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSAHAAYAQSKLALVLFTY 147

Query: 199 ELGRRLL--GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIG 252
            L R L   G+ V    VDPG+V TD+ +H+      TR  +    W   K P  G
Sbjct: 148 HLQRLLAAEGSHVTANVVDPGVVHTDLYQHVFW---GTRLVMKLFSWLLFKTPREG 200


>UniRef50_Q0S547 Cluster: Dehydrogenase; n=1; Rhodococcus sp.
           RHA1|Rep: Dehydrogenase - Rhodococcus sp. (strain RHA1)
          Length = 300

 Score = 97.9 bits (233), Expect = 3e-19
 Identities = 78/286 (27%), Positives = 114/286 (39%), Gaps = 16/286 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RT+++TGA SG+G    +  A+RGA V +  RD  K +    ++   T+   +     DL
Sbjct: 10  RTMVVTGATSGLGLETCRQLARRGATVVLVGRDQDKIDAVIAELSENTDRDRLNSALADL 69

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           +S    R          P + VLVNNAG+    + +T DG E    V             
Sbjct: 70  SSLDRARRLSEELLHRFPRIDVLVNNAGIDVGHRQLTVDGVEEMFAVNYLAPFVLATSLA 129

Query: 146 XXXKXXXXXXXXXX---------XXXXHQRGRIHKQDLN-MSENYDASAAYSQSKLANLL 195
                                      H+ G +   DL+   + +    AY+ SKLA  L
Sbjct: 130 PAMAQASTADAAGYRHPARIVDVSSSGHRGGHLDFDDLDGTKDTFHGQRAYNNSKLALTL 189

Query: 196 FARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIY-PLFWPFMKKPEIGGQ 254
           F REL RR     +     DPG V     R  S+ + +  + +   L  PF         
Sbjct: 190 FTRELARRSDPARLVVNCADPGFV-----RGTSLGRGLFGYQVVGTLLTPFASDVAKAAD 244

Query: 255 TVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEA 300
           TVV  A   +     G+Y    K  +PS++A+D ELA  LW  +EA
Sbjct: 245 TVVWTATATESGKFTGEYVKGCKVVQPSKDARDAELAARLWDATEA 290


>UniRef50_A6WFS0 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Kineococcus radiotolerans SRS30216|Rep: Short-chain
           dehydrogenase/reductase SDR - Kineococcus radiotolerans
           SRS30216
          Length = 288

 Score = 96.7 bits (230), Expect = 7e-19
 Identities = 79/271 (29%), Positives = 114/271 (42%), Gaps = 12/271 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RT+++TGA+SGIG AAA+ FA+ GA+V    RD     E+ R +  E   + +     D 
Sbjct: 18  RTVVVTGASSGIGAAAARRFARAGARVVPVGRD----PERTRALAAELGVEPLL---VDA 70

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A    +R            + VL NNAG     +  T DG ET   V             
Sbjct: 71  ARLDDVRRLAGDLLERCDRIDVLANNAGGSSARRTETPDGHETTFQVNHLAPFLLTALLR 130

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE-NYDASAAYSQSKLANLLFARELGRRL 204
              +              +  GR+   DL+     Y     Y+ +KL N+LF R L RRL
Sbjct: 131 ERIEATPGARVVTTSSAANLLGRVDLDDLDSRRGRYRGFRVYATTKLENVLFTRALSRRL 190

Query: 205 LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPK 264
            GT  A+    PG+V T   R  S++  V   +  PL       PE G + +   A+ P 
Sbjct: 191 GGTATAS-CFHPGVVATRFARD-SVVAGV--LYRTPLRRVLAVTPEEGAEPLWRLAVRPD 246

Query: 265 LKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
            +   G Y   +     +++A D ELA+ LW
Sbjct: 247 PETVDGAYLDRLAPGRVNRQADDVELAEQLW 277


>UniRef50_Q026V1 Cluster: Transcriptional regulator, Fis family;
           n=1; Solibacter usitatus Ellin6076|Rep: Transcriptional
           regulator, Fis family - Solibacter usitatus (strain
           Ellin6076)
          Length = 311

 Score = 96.3 bits (229), Expect = 9e-19
 Identities = 75/287 (26%), Positives = 120/287 (41%), Gaps = 13/287 (4%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           ++ ++ITG   GIG+A A   AK GA   +  RD  + E  + +I  ++ N+ V     D
Sbjct: 6   SQIVLITGGTGGIGQAIAVRMAKLGATTIVVGRDQARGEAAKAEIRTQSGNRSVELMLAD 65

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           L+S   IR     F      L VLVNN G +   +  T DG E  L +            
Sbjct: 66  LSSQGDIRRLAGEFMARYGRLDVLVNNVGGLYGKRWETVDGIECTLALNHLCPFLLTHLL 125

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGR-IHKQDLNMSENYDASAAYSQSKLANLLFARELGRR 203
               +              H+  + ++  D + +        YSQSKLANLLF  E+ RR
Sbjct: 126 LPVLRAGAPSRIVNINSEGHRAAKSVNFGDFDAARWKRGFLIYSQSKLANLLFTFEMARR 185

Query: 204 LLGTGVATIAVDPGLVDTDITRHM---------SMMKSVTRFFIYPLFW--PFMKKPEIG 252
           L  + +   AV PG+VDT + R            ++     F    + +        E  
Sbjct: 186 LSPSEITVNAVHPGIVDTQLFRRFIEERFTLIGGVLSKAAAFVARKVAYRISHFDTVETA 245

Query: 253 GQTVVHAALDPKLKDCAGDYY-VDMKKAEPSQEAQDFELAQWLWRVS 298
            +  V+ A   ++    G Y+ ++ K  E S  + D +L++ +WR+S
Sbjct: 246 AECPVYLASSSEVAGITGKYFGLNKKIVETSAASLDADLSREVWRMS 292


>UniRef50_UPI0000D573DB Cluster: PREDICTED: similar to CG7675-PB,
           isoform B; n=2; Tribolium castaneum|Rep: PREDICTED:
           similar to CG7675-PB, isoform B - Tribolium castaneum
          Length = 340

 Score = 95.1 bits (226), Expect = 2e-18
 Identities = 76/291 (26%), Positives = 121/291 (41%), Gaps = 12/291 (4%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + +T I+TG  SGIG   A   A RG +V +A R+     + +  I+  TNN  +  +  
Sbjct: 46  NGKTAIVTGGGSGIGFETALQLASRGCRVIIADRE--DATKTKNKIIDLTNNTNIETKHL 103

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXX-XXXXXX 142
           DL S  SIR F       E  L +L+NNAG        T DG    + V           
Sbjct: 104 DLTSFQSIRRFAKEINETEDRLDILINNAGAGSVGNKHTDDGLHITMQVNHFGPFLLTHL 163

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-----YDASAAYSQSKLANLLFA 197
                 K                   +  ++LN   +     + +S  Y  SKL N++ A
Sbjct: 164 LADLLKKSAPSRIIFVSSATAFFWNNLTVKNLNYPSDHPMTFFRSSFIYGNSKLCNIIAA 223

Query: 198 RELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRF---FIYPLFWPFMKK-PEIGG 253
                RL   GV + ++ PGLV+T+I    + +  +  F   F   + + + KK P+ G 
Sbjct: 224 NGFAERLSQFGVTSNSLHPGLVNTEIHLKSARILGIETFGKLFANTILYLYGKKSPKEGA 283

Query: 254 QTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKL 304
           QT +  A+   L++  G ++ D +      +A + +    +W  SE  TKL
Sbjct: 284 QTTIALAVSNHLQNVTGKHFWDCRTFIQPPKAWNRKFCTEIWEKSEELTKL 334


>UniRef50_A6LYK8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Clostridium beijerinckii NCIMB 8052
          Length = 327

 Score = 93.9 bits (223), Expect = 5e-18
 Identities = 62/202 (30%), Positives = 88/202 (43%), Gaps = 7/202 (3%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYC 80
           +    +  I+TG  SGIG   AK  A+ GA V +  RD++K +    +I        +  
Sbjct: 26  INLKGKIAIVTGGYSGIGMETAKVLAEAGATVIIPARDIEKAKGAMDNI------PNIEI 79

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXX 140
              DL    SI  F  +F   +  LH+L+N+AG+M PP    K G+E+Q           
Sbjct: 80  EHLDLMDPMSIDSFAQKFINSQRSLHILINSAGIMAPPLIRDKRGYESQFATNHLGHFQL 139

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE-NYDASAAYSQSKLANLLFARE 199
                   K               + G ++  D N  +  YD+  AY+QSK AN LFA E
Sbjct: 140 TARLWPALKNAKSARVISVSSRAQRLGGVNFDDPNFQKTEYDSWKAYAQSKSANSLFAVE 199

Query: 200 LGRRLLGTGVATIAVDPGLVDT 221
           L R     GV   +V PGL+ T
Sbjct: 200 LDRLGKTHGVRAFSVHPGLIPT 221


>UniRef50_Q54I93 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 317

 Score = 93.9 bits (223), Expect = 5e-18
 Identities = 80/290 (27%), Positives = 135/290 (46%), Gaps = 19/290 (6%)

Query: 28  IIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLET-NNKYVYCRPCDLA 86
           +I+TG++ G+GK  +   AK    V +A RD+ K +    +I+  T NNK V     DL+
Sbjct: 33  VIVTGSSDGLGKVVSGMLAKTNYFVILANRDLIKAKLVLDEILSTTPNNKNVISMKLDLS 92

Query: 87  STASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXX 146
           S  SI+EFV +F+     L VL+NNAG+  PP  +  +GFE+QL V              
Sbjct: 93  SFDSIKEFVNQFEKLNLQLDVLINNAGIYTPPFSL-PEGFESQLMV--NHLGPFLLTNLL 149

Query: 147 XXKXXXXXXXXXXXXXXHQRGRI-HKQDLNMS--ENYDASAAYSQSKLANLLFARELGR- 202
             K              H+   I + +DL+    ++Y+A   YS SKL  +LF +EL R 
Sbjct: 150 INKFTENARIINLSSIAHKNSEIFNVEDLSCKSIDSYNAIKRYSNSKLYAILFTKELNRI 209

Query: 203 -RLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRF--FIYPLFWPFMKKPEIGGQTVVHA 259
            +   + +  +++ PG++ T      ++ K++  +   +  +  PF          +   
Sbjct: 210 FKKNNSKIIALSLHPGVIST-----TNLFKNIPNYIKLLLTISKPFTTTINTASTAIYRL 264

Query: 260 AL--DPKLKDCAGDYYVDMK-KAEPSQEAQDFELAQWLWRVSEAWTKLDE 306
           A+  DP+L    G  Y ++    +P  +A   E  + LW  S  + K+D+
Sbjct: 265 AVGADPELPLLTGGEYFNINVLVDPIPQALSQENWRLLWAKSCEYCKIDD 314


>UniRef50_A0DVI8 Cluster: Chromosome undetermined scaffold_66, whole
           genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_66,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 324

 Score = 93.9 bits (223), Expect = 5e-18
 Identities = 86/312 (27%), Positives = 134/312 (42%), Gaps = 25/312 (8%)

Query: 9   RDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACR-DVKKCEEQRR 67
           R Y+ G   +      N TI+ITG + G+G+   K  AK   ++   CR +  +  EQ  
Sbjct: 20  RIYFRGKKCEAYRDISNMTILITGGSKGLGQETIKQLAKFNCRIIFGCRSNPNEFLEQLL 79

Query: 68  DIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPK-GVTKDGF 126
           +   ++  +Y    P DL S  SI++F AR K E   + V++NNAG+M   K   T+ G 
Sbjct: 80  ESFPQSKIQYF---PLDLQSWNSIKQFAARVKQEVDRIDVVINNAGIMGTLKREFTQYGI 136

Query: 127 ETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS--------E 178
           E Q G                 K              H    +   DLN           
Sbjct: 137 EAQFGTNYLGPFFLNHLLLDLLKKSNSPRIINVSSIAHVFQNLDFDDLNCDRWANSLFWS 196

Query: 179 NYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHM--SMMKSVTRF 236
                 AY  +K A +L A+E   R   TGV   A+ PG+V T++ +H   +   ++   
Sbjct: 197 RIYTYRAYGNTKFAQILNAQEYSER---TGVKACALHPGVVRTEVLQHQLSAWWFNLIMS 253

Query: 237 FIYPLFWPFMKKPEIGGQTVVHAAL--DPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWL 294
             +P++  F K    G QT++   +  D +L D  G +Y D K A+    ++  E A+ L
Sbjct: 254 IAWPIYSFFTKDSYYGCQTILFCLMIKDEELVD--GGFYKDCKLAKARFTSR--EKAKML 309

Query: 295 WRVS-EAWTKLD 305
           W VS +  +K+D
Sbjct: 310 WDVSLQLISKID 321


>UniRef50_A3Q3R2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium sp. (strain
           JLS)
          Length = 271

 Score = 93.5 bits (222), Expect = 6e-18
 Identities = 69/199 (34%), Positives = 92/199 (46%), Gaps = 18/199 (9%)

Query: 28  IIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAS 87
           II+TG NSG+G+A A   A  G +V +ACR + K      D     + + V  R  DLA 
Sbjct: 3   IIVTGGNSGVGRATASAMAAEGHEVVIACRTMSK----GYDAAASMSGR-VDVRELDLAD 57

Query: 88  TASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXXX 147
             S+R    +F     ++ VLVNNAGV+  P   T DGFE  +G                
Sbjct: 58  LTSVR----KFADTVDYVDVLVNNAGVLGLPLTRTADGFEAHMGTNHLGHFALTCLLGDR 113

Query: 148 XKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE-NYDASAAYSQSKLANLLFARELGRRLLG 206
            +              +   R+H  DLN  +  Y+  +AY +SKLANLLF  EL  R   
Sbjct: 114 IR----DRVVSVASTNYTTARMHFDDLNWQQRKYNPWSAYGESKLANLLFVHELVAR--- 166

Query: 207 TGVATIAVDPGLVDTDITR 225
            G    A DPG+ +T ITR
Sbjct: 167 -GKTAYASDPGMTNTAITR 184


>UniRef50_A3VT62 Cluster: Dehydrogenase; n=1; Parvularcula
           bermudensis HTCC2503|Rep: Dehydrogenase - Parvularcula
           bermudensis HTCC2503
          Length = 313

 Score = 93.1 bits (221), Expect = 9e-18
 Identities = 81/287 (28%), Positives = 116/287 (40%), Gaps = 12/287 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +T  ITGANSGIG  AA+    R A V M CR+  K E  R  +              DL
Sbjct: 22  KTFAITGANSGIGLEAARYLGGRNATVLMLCRNASKAESARNALRQSAPGGKYETISLDL 81

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVME-PPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           A  +++       +     L  L+ NAGVM  P + +TKDGFE Q  V            
Sbjct: 82  ADFSTLSPATDAIRQATDRLDGLILNAGVMMLPRRQITKDGFEMQYQVNVLSHFALAAAL 141

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
               +              H        DL  +  Y  +++Y++SKLA+L+   EL RRL
Sbjct: 142 ADLVETASGRFVWLSSIAHHYAKHPKLTDLGYAAGYSPTSSYAKSKLADLMLGLELHRRL 201

Query: 205 --LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
              G    +    PG  DT++    +   ++    I P    F +  E G    V AA  
Sbjct: 202 SAAGKSAGSYIAHPGYSDTNL--QSAGPGAILGTLIKPFTMIFSQPAEKGALPTVLAAAY 259

Query: 263 PKLKD---CAGDYYVDMK----KAEPSQEAQDFELAQWLWRVSEAWT 302
           PK +         + +MK    +A     A+D ++A+ LW V E  T
Sbjct: 260 PKAQPGVLYGPTGFQEMKGPVGEAAIKPWAKDPQVAKQLWSVCEEAT 306


>UniRef50_UPI00006CC409 Cluster: oxidoreductase, short chain
           dehydrogenase/reductase family protein; n=1; Tetrahymena
           thermophila SB210|Rep: oxidoreductase, short chain
           dehydrogenase/reductase family protein - Tetrahymena
           thermophila SB210
          Length = 325

 Score = 92.3 bits (219), Expect = 1e-17
 Identities = 75/269 (27%), Positives = 120/269 (44%), Gaps = 16/269 (5%)

Query: 18  DRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLE-TNNK 76
           D  V    + IIITGANSGIG +AA   A++GA + + CR+ ++ EE  +++  E +NNK
Sbjct: 33  DTQVDLSGQHIIITGANSGIGYSAALQLAQKGAFIHLVCRNKQRGEEALQNLQKEISNNK 92

Query: 77  YVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQL-----G 131
            V    CD++  +SIR+FV  +      L  LV NAG M   +  TKDG E        G
Sbjct: 93  NVQLHLCDMSDFSSIRKFVDEYNQLGVTLDGLVQNAGTMIHERQTTKDGLEYNFATNVAG 152

Query: 132 VXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS--ENYDASAAYSQS 189
           V                +                  ++   DLNMS  + +D  A Y+++
Sbjct: 153 VFLMNELFVPLLEKTYKQTQRNPKIILVSSGGMYTQKLEADDLNMSKEKKFDGQAQYAKN 212

Query: 190 KLANLLFARELGRRLL-GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKK 248
           K   ++   +  +      G+   ++ PG VDT +     + +++  F  Y  F   ++K
Sbjct: 213 KRQQVVLCEKWTKLYTQSKGIQFYSMHPGWVDTPV-----LPQAMPDF--YKRFKDDLRK 265

Query: 249 PEIGGQTVVHAALDPKLKDCAGDYYVDMK 277
            E G  T+      P  +  +G +Y D K
Sbjct: 266 CEEGSDTIFWLQCMPASRLESGGFYFDRK 294


>UniRef50_A1G3M7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Salinispora|Rep: Short-chain
           dehydrogenase/reductase SDR - Salinispora arenicola
           CNS205
          Length = 288

 Score = 91.5 bits (217), Expect = 3e-17
 Identities = 78/283 (27%), Positives = 115/283 (40%), Gaps = 16/283 (5%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + R +++TGA+SGIG AAA D A RG +V +  RD  + +     +   T  +    R  
Sbjct: 6   ERRVVVVTGASSGIGLAAAIDLAYRGDQVVLVGRDSARLQSAAGQVREATGERPELFR-A 64

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           D A    +R    R +     + VL NNAG +      T DG+E  L V           
Sbjct: 65  DFAVLDDVRSLAERLRTAYDRIGVLANNAGTIALHPTTTVDGYE--LSVQANHLAPFLLT 122

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS-ENYDASAAYSQSKLANLLFARELGR 202
                +              H+ G ++  DLN +   +   +AYS SK AN+LF  E  R
Sbjct: 123 NLLRDRLGRVVVTASAA---HRSGLLNPNDLNQTLHRFRPMSAYSASKRANILFTVEAAR 179

Query: 203 RLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
           R     + T    PG+V T       ++    R  + P      + P  G +T+V  A  
Sbjct: 180 RW--PDLPTYCFHPGIVRTRFASDSRLITFAMR--LLPA-----RSPAKGAETLVWLANQ 230

Query: 263 PKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLD 305
              +  +G YY D +   P   A D +LA  LW  S     +D
Sbjct: 231 APERLRSGGYYQDRRLRHPHATATDPQLAAQLWTASAKAVGID 273


>UniRef50_A6QU72 Cluster: Predicted protein; n=2; Onygenales|Rep:
           Predicted protein - Ajellomyces capsulatus NAm1
          Length = 264

 Score = 91.5 bits (217), Expect = 3e-17
 Identities = 60/214 (28%), Positives = 96/214 (44%), Gaps = 7/214 (3%)

Query: 18  DRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKY 77
           DR     ++  ++TG++ GIG    +  A  G KV++  RD++K +E  ++I LE +   
Sbjct: 32  DRIGTMKDKVFLLTGSSGGIGIETGRALAATGGKVYLGVRDLEKGKEALKEI-LEPDR-- 88

Query: 78  VYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGV----X 133
           V     D  S  S+R     F  +   L+VLVNNAG+M  P+  T DGFE+QL +     
Sbjct: 89  VELLELDTGSVESVRTAAKAFLSKSTQLNVLVNNAGIMACPEAKTADGFESQLVINYLGH 148

Query: 134 XXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLAN 193
                                         H  G +   ++N+   Y+A  AY  +K A 
Sbjct: 149 FLLYKLLEQTLLSSSTPEFASRVVNVASAGHHMGSVVLDNINLDGEYEAWKAYGNAKTAC 208

Query: 194 LLFARELGRRLLGTGVATIAVDPGLVDTDITRHM 227
           +    E+ RR    G+  +++ PG V T + RH+
Sbjct: 209 IWMTNEIERRYGSKGLHGLSLMPGGVATGLQRHV 242


>UniRef50_A7D2G2 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Halorubrum lacusprofundi ATCC 49239|Rep:
           Short-chain dehydrogenase/reductase SDR - Halorubrum
           lacusprofundi ATCC 49239
          Length = 290

 Score = 91.5 bits (217), Expect = 3e-17
 Identities = 72/282 (25%), Positives = 113/282 (40%), Gaps = 4/282 (1%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           +R I +TGA SGIG+ AA   A+RGA V    R+ ++ E    +         +     D
Sbjct: 8   DRVIALTGATSGIGRRAAVTLAERGATVAAVGRNRERGEALAAESDAAAGT--IRFHRAD 65

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           LA+ +++R+  A  +     L VL +NAG+    +  T DG E  L V            
Sbjct: 66  LATQSAVRDLAAELRESYDRLDVLAHNAGLSVRSRTETADGIELTLAVNHLAPYLLTREL 125

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
                              H+R  +   DL  ++ YD   AY++SKLAN+ F  EL  R+
Sbjct: 126 FDQLAGSAPARVVVTASDLHRRATLDFDDLQFADGYDPLEAYARSKLANVAFTLELADRI 185

Query: 205 -LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDP 263
               GV    + PG V +      + +++     I  L              +V     P
Sbjct: 186 PEAAGVTANCLHPGFVPSTNLFRDAALRTRLAVRIAGLLPGVGTTRRAAADRLVRLVASP 245

Query: 264 KLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLD 305
           +  +  G  YV  ++  P+ +  D E  + LW VS     +D
Sbjct: 246 EYAERTG-RYVGEEEMTPADDTVDSETRERLWSVSADLVGID 286


>UniRef50_Q03326 Cluster: Probable oxidoreductase; n=12;
           Bacteria|Rep: Probable oxidoreductase - Streptomyces
           antibioticus
          Length = 298

 Score = 91.5 bits (217), Expect = 3e-17
 Identities = 73/270 (27%), Positives = 113/270 (41%), Gaps = 14/270 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R  ++TG  SG+G    +  A  GA+V +A R     E   +++        V     DL
Sbjct: 6   RRAVVTGGASGLGAETVRALAAAGAEVTVATRRPLSAEPLVQELAAAGGAGRVTAEALDL 65

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVME-PPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           +  AS+  F   ++G    L +LV NAG+M  P + +  +G+E QL              
Sbjct: 66  SDPASVESFARAWRGP---LDILVANAGIMALPTRTLAPNGWEMQLATNYLGHFALATGL 122

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-YDASAAYSQSKLANLLFARELGRR 203
               +              H       +D + +   YD   AY QSK A++LF     RR
Sbjct: 123 HAALRDAGSARIVVVSSGAHLDAPFDFEDAHFARRPYDPWVAYGQSKAADVLFTVG-ARR 181

Query: 204 LLGTGVATIAVDPGLVDTDITRHM--SMMKSV----TRFFIYPLFWPFMKKPEIGGQTVV 257
               G+   A++PG + T + RH+    M++      +  + PL  P+ K PE G  T V
Sbjct: 182 WAADGITVNALNPGYILTRLQRHVDDETMRAFGVMDDQGNVKPL--PYYKTPEQGAATSV 239

Query: 258 HAALDPKLKDCAGDYYVDMKKAEPSQEAQD 287
             A  P LK   G Y+ D ++A   Q  +D
Sbjct: 240 LLAASPLLKGVTGRYFEDNQEARTVQGQED 269


>UniRef50_UPI0000DB6DB5 Cluster: PREDICTED: similar to CG11200-PB,
           isoform B; n=1; Apis mellifera|Rep: PREDICTED: similar
           to CG11200-PB, isoform B - Apis mellifera
          Length = 297

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 72/282 (25%), Positives = 121/282 (42%), Gaps = 23/282 (8%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDV---KKCEEQRRDIVLETNNKYVYCRP 82
           R  I+TG + GIG    K F +   +V +ACR     +K   Q R   + T    +Y   
Sbjct: 15  RIAIVTGGSRGIGYEVVKAFLELDMEVIIACRTPFAGEKAILQIRKSGINTGKAKIY--K 72

Query: 83  CDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX 142
            D +S  S+++F    K +   +HVL+NNAGVM  P   T D FE Q  V          
Sbjct: 73  LDNSSLQSVKQFAIEIKKDYKQIHVLINNAGVMFCPYQETVDNFEQQWAVNYLSHFLLTA 132

Query: 143 XXXXXXKXXXX----XXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAR 198
                 K                  H  G+I+  D+N    +    AY+QSKLA  +F +
Sbjct: 133 ELLPLLKAGGLPEQCSRIVNITSCAHLIGKINFNDINNRNKFLTKYAYAQSKLAQEIFTK 192

Query: 199 ELGRRLLGTG--VATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTV 256
            L   L      +   +V PG+V T++            F +  L +   + P+ G  ++
Sbjct: 193 GLQNLLKEKQYYIQVYSVHPGIVFTEL------------FIVNILIFILFQTPKQGALSI 240

Query: 257 VHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           ++AA++  +++C G Y  +   ++   +A +  + + L+ +S
Sbjct: 241 IYAAINKTIENCGGIYITNCHSSQAHSDASNLSIQKKLFDLS 282


>UniRef50_UPI000049A4BD Cluster: short chain dehydrogenase family
           protein; n=1; Entamoeba histolytica HM-1:IMSS|Rep: short
           chain dehydrogenase family protein - Entamoeba
           histolytica HM-1:IMSS
          Length = 311

 Score = 91.1 bits (216), Expect = 3e-17
 Identities = 63/278 (22%), Positives = 116/278 (41%), Gaps = 7/278 (2%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + ++ITG   G+GK   +  A  GA +    R+ +  ++   +I     +  +     DL
Sbjct: 38  KVVVITGGTHGMGKVIVEQLADTGATIISCSRNNEIAQKVIEEIKSVHKSCNIIHEHLDL 97

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           +   S+++       +   + +L+NNAGVM  P G TK G+ETQ+GV             
Sbjct: 98  SDLDSVKQCAENILNKYHEIDILINNAGVMRVPYGKTKQGYETQMGVNYLGHFLLTQKLL 157

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
              +                  R     +   + + +   Y +SKL+  + A+EL +R  
Sbjct: 158 SALEKCNGRVINYSSVASKLYHRKEFPFVAEEKGFFSMRWYCESKLSMAIMAQELAKR-- 215

Query: 206 GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKL 265
              +  +++ PG V+T + +   +     ++  +P+     K P  G QT +H      +
Sbjct: 216 NDNIIAVSLHPGCVNTALWQFFPIW---LQYLCWPILQVIFKTPLEGAQTCLHLIHSESI 272

Query: 266 KDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTK 303
            +  G YY D K A+ ++   D ++   LW  S   TK
Sbjct: 273 TN--GAYYADCKPAKHNKIMDDSDICTKLWNDSVDATK 308


>UniRef50_Q5DAF6 Cluster: SJCHGC01149 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC01149 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 326

 Score = 90.6 bits (215), Expect = 5e-17
 Identities = 71/219 (32%), Positives = 98/219 (44%), Gaps = 16/219 (7%)

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DLA   SIREF      +   L +L++NAG+M      T DGFE Q+GV           
Sbjct: 102 DLACLESIREFAKNILRQYTRLDILIHNAGMMATSYMETHDGFELQMGVNHLGPVLLTEL 161

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNM-SENYDASAAYSQSKLANLLFARELGR 202
                               +Q+G I   +LN+  E Y    AY+QSKLAN+++ REL +
Sbjct: 162 LLPLLYNGTSSRIIVIASNLYQQGEIDVNNLNLRGEQYGPFKAYNQSKLANVMYVRELAK 221

Query: 203 RLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMK-KPEIGGQTVVHAAL 261
            L G  V  ++V PG V T+I        S T    Y LF   +   P  G QT ++  L
Sbjct: 222 HLDGLKVIPMSVHPGAVRTEI--------SYTGDHRYQLFLRAVGISPWEGAQTALYCTL 273

Query: 262 --DPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
             DP      G YY + ++ E   +A +  L + LW VS
Sbjct: 274 IEDP----VPGGYYSNCEREELIDKAMNESLGRRLWNVS 308



 Score = 46.0 bits (104), Expect = 0.001
 Identities = 19/40 (47%), Positives = 27/40 (67%)

Query: 22 RADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKK 61
          R D + +I+TGAN G G   + + A+RG  V MACRD++K
Sbjct: 16 RLDGKLVIVTGANIGCGLELSGELARRGCTVIMACRDLEK 55


>UniRef50_Q19062 Cluster: Dehydrogenases, short chain protein 7;
           n=10; cellular organisms|Rep: Dehydrogenases, short
           chain protein 7 - Caenorhabditis elegans
          Length = 329

 Score = 90.6 bits (215), Expect = 5e-17
 Identities = 78/295 (26%), Positives = 130/295 (44%), Gaps = 19/295 (6%)

Query: 19  RSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYV 78
           + V    +T ++TG  SGIG   A+  +  GA V M  R++++ E+ ++ IV E N+  +
Sbjct: 22  KGVNLAGKTFVVTGTTSGIGIETARSLSLNGAHVVMLNRNLEESEKLKKKIVEEMNDAEI 81

Query: 79  YCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXX 138
               CDL S  S+++    +  ++  +H L+ NAGV       T DG E+   +      
Sbjct: 82  DIIECDLNSLHSVKKAAEVYISKKWSIHCLILNAGVFGTASKTTVDGLESHFAINHLSHF 141

Query: 139 XXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIH-----KQDLNM---SENYDAS--AAYSQ 188
                     +              H    +      ++ L +     + DAS    YS+
Sbjct: 142 LLIQELLPIVRQSIPSRIVLVSSSVHATCGVSPEMSIEEKLKILCPESSSDASWFRLYSR 201

Query: 189 SKLANLLFARELGRRLLGTGVATIAVDPGL-VDTDITRHMSMMKSVTRFFIYPLFWPFMK 247
           SK+ N+L A +L R     G++T +V PG  V T I R  S + S+       L  PF K
Sbjct: 202 SKMCNMLVAFKLHRDEYHNGISTYSVHPGNGVRTSIFRD-SWLVSIASI----LSTPFTK 256

Query: 248 KPEIGGQTVVHAALDPKLKDCAGDYY---VDMKKAEPSQEAQDFELAQWLWRVSE 299
               G  T V+ A  P++ + +G Y+    D +K    + A+D +L   LW+ S+
Sbjct: 257 NISQGASTTVYCAGHPEVANVSGKYWDSNWDDEKGLYEEVARDEQLQDALWKHSD 311


>UniRef50_A5K293 Cluster: Oxidoreductase, short-chain dehydrogenase
           family, putative; n=5; Plasmodium|Rep: Oxidoreductase,
           short-chain dehydrogenase family, putative - Plasmodium
           vivax
          Length = 395

 Score = 90.6 bits (215), Expect = 5e-17
 Identities = 69/263 (26%), Positives = 116/263 (44%), Gaps = 17/263 (6%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + +I+TG   GIG AA  +F K G +V +ACR V+  E  + D++    +  ++C   DL
Sbjct: 99  KCVIVTGGYKGIGLAAVTEFVKLGCEVVLACRSVEHMEFVKTDLLTRYPDAKIHCVQLDL 158

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGV----MEPPKGVTKDGFETQLGVXXXXXXXXX 141
           AS  S+    ++   + P + +LVNNAG     +E   G+ +  F   LG          
Sbjct: 159 ASYKSVESCASQILSKFPKIDILVNNAGFVSQKLEYVNGLERTFFINYLGHFYLTKLLHK 218

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQ----SKLANLLFA 197
                                          + N ++N +++  Y +    SKL  L + 
Sbjct: 219 RIVASDTLVVNLSSIAHSMLRESDVNYNFICEKNSTKNTNSNLLYRREYNFSKLCMLYYT 278

Query: 198 RELGRRLLG--TGVATIAVDPGLVDTDITRH-MSMMKSVTRFFIYPLFWPFMKKPEIGGQ 254
           ++L RR     T   T++++PGLV T++ R+  S  +++ +  I      F K P  G Q
Sbjct: 279 QQLQRRFENEKTKACTVSINPGLVRTELFRNEQSWFRALAKNLI------FSKSPLQGAQ 332

Query: 255 TVVHAALDPKLKDCAGDYYVDMK 277
           T+++  L  + K   G YY D K
Sbjct: 333 TILYVCLLDREKLAKGSYYSDCK 355


>UniRef50_Q4UJ91 Cluster: Dehydrogenase/reductase (SDR family)
           X-linked; n=1; Homo sapiens|Rep: Dehydrogenase/reductase
           (SDR family) X-linked - Homo sapiens (Human)
          Length = 266

 Score = 90.6 bits (215), Expect = 5e-17
 Identities = 54/124 (43%), Positives = 69/124 (55%), Gaps = 1/124 (0%)

Query: 9   RDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRD 68
           RD    PP     R D R  I+TG   GIG + AK  A+ G  V +A  +  K ++    
Sbjct: 105 RDLDPYPPQVFPPRPD-RVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSK 163

Query: 69  IVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFET 128
           I  ET N  V    CDLAS  SIR+FV +FK ++  LHVL+NNAGVM  P+  T+DGFE 
Sbjct: 164 IKEETLNDKVEFLYCDLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEE 223

Query: 129 QLGV 132
             G+
Sbjct: 224 HFGL 227


>UniRef50_A6STP3 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 309

 Score = 90.6 bits (215), Expect = 5e-17
 Identities = 75/289 (25%), Positives = 120/289 (41%), Gaps = 13/289 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKV-FMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           + II+TG NSG+GK      AK    + +M  R   K EE   +I     N  +     D
Sbjct: 19  KVIIVTGGNSGLGKETVLQLAKHNPHLLYMGARSKAKAEEAIAEIKTTVPNANIKFLEID 78

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           ++S +S++     F  E   L +LVNNAGVM  P G+T+DG+E+Q G             
Sbjct: 79  ISSLSSVKRGADAFLAENDRLDILVNNAGVMGLPPGLTEDGYESQFGTNHMGPALFTKLL 138

Query: 145 XXXXKXXXXX---------XXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLL 195
               +                          G +  Q+     +   +  Y QSKLANL 
Sbjct: 139 LPTLQKTSLSPNADVRIVNISSEALKFGPPTGLVLAQNKTSLASLSGAQRYGQSKLANLY 198

Query: 196 FARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQT 255
           F++ L ++     + T A+ PG+V T IT + +       +     F  F+     G + 
Sbjct: 199 FSQILAKKY--PNIKTNAIHPGMVRTGITTNTTNNYWYLSWVFAIGFKMFLLNIHDGAKP 256

Query: 256 VVHAALDPKLKDCAGDYYV-DMKKAEPSQEAQDFELAQWLWRVSEAWTK 303
            + AA   K    +G +Y   + + + +   ++ +LA  LW  +EA  K
Sbjct: 257 QLFAATGKKEVVKSGAFYFPGVSEWDGNAITKNSKLADELWNWTEAELK 305


>UniRef50_Q54KS0 Cluster: Putative uncharacterized protein; n=3;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 309

 Score = 90.2 bits (214), Expect = 6e-17
 Identities = 87/299 (29%), Positives = 127/299 (42%), Gaps = 33/299 (11%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGA---KVFMACRDVKKCEEQRRDIVLETNNKY-VY 79
           + + II TG+  GIG        +      K  +  R+++K E  ++ +  E N K  + 
Sbjct: 2   EKKVIIFTGSTDGIGLLVINHLVREKCENYKFILPVRNLEKGELLKKQLK-EINEKVDIT 60

Query: 80  CRPCDLASTASIREFVARFKGEE-PHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXX 138
               DL+S  SIR FV  F     PHL +LVNNAG+M+P    T DGFE+ +GV      
Sbjct: 61  LMEMDLSSFESIRNFVKNFNQLNLPHLDILVNNAGIMQPRFIKTVDGFESTIGVNHLGTS 120

Query: 139 XXXXXXXXXXKXXXXXXXXXXXXX--------------XHQRGRIHKQDL----NMSENY 180
                     K                            HQR  ++   L    N S N+
Sbjct: 121 LLTLLLLKNFKNSSNYENSNGASSNNEDFGNIVILSSEFHQREPLNFDKLLLTDNDSSNF 180

Query: 181 DASAAYSQSKLANLLFARELGRR---LLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFF 237
           D    YS+SKL NLLF+ EL  R   L    +   ++ PG + T I R +S     TR  
Sbjct: 181 DTLREYSKSKLCNLLFSMELHNRLDNLKNNNIRVNSLHPGYLRTPINRDLSWF---TRHI 237

Query: 238 IYPL-FWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
           I P+ F+ +  K E     +V+  L     + +G Y+   K+  PS  A + E ++ LW
Sbjct: 238 IAPIFFFGYGSKTEDTINGIVN--LIENNSNHSGKYFSISKEISPSPFASNLENSKLLW 294


>UniRef50_Q0CJ32 Cluster: Putative uncharacterized protein; n=3;
           Pezizomycotina|Rep: Putative uncharacterized protein -
           Aspergillus terreus (strain NIH 2624)
          Length = 312

 Score = 90.2 bits (214), Expect = 6e-17
 Identities = 63/231 (27%), Positives = 96/231 (41%), Gaps = 13/231 (5%)

Query: 3   VSFLFNRDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRG-AKVFMACRDVKK 61
           +SF+F +     P  D       + I++TG N+G+GK   K  AK    K++M  R   K
Sbjct: 1   MSFIFRQKVTYNPDKDIP-DLGGKVILVTGGNNGLGKETIKQMAKHNPTKIYMGARSKAK 59

Query: 62  CEEQRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGV 121
                 ++  +  +  +     DLAS +SI+   A F  E   LH+LVNNAGV   P G+
Sbjct: 60  ASAAIAELKEQVPSANIIHLEIDLASFSSIKRAAATFLAENDRLHILVNNAGVFATPPGL 119

Query: 122 TKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXX---------XXXXXXXXHQRGRIHKQ 172
           T+DG+E Q G                 +                        + G +  +
Sbjct: 120 TEDGYEVQFGTNYMGPALFTKLLLPIMEKTTTISDGDVRIINISSEIYTLAPKGGLLLAR 179

Query: 173 DLNMSENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDI 223
                      A Y QSKLAN+ F +   +R     + ++A+ PGLV T+I
Sbjct: 180 VKTPLTEISTVARYGQSKLANIYFTKSYAKRY--PAIKSVALHPGLVQTNI 228


>UniRef50_Q97DJ3 Cluster: Short-chain alcohol dehydrogenase family
           protein; n=2; Bacteria|Rep: Short-chain alcohol
           dehydrogenase family protein - Clostridium
           acetobutylicum
          Length = 291

 Score = 89.4 bits (212), Expect = 1e-16
 Identities = 70/285 (24%), Positives = 117/285 (41%), Gaps = 11/285 (3%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RTI ITGA SG+GK  A +  KR A + +  R+ ++ E  ++ +        +     DL
Sbjct: 5   RTIAITGATSGLGKLVAIELVKRDAHLILTARNKERAEATKKMLESINPKAKIDFFFGDL 64

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXX---XXXXXX 142
           +    ++      K   P + VLVNNAG+    + VT DG    + V             
Sbjct: 65  SVMRDVKRVGEEIKAVHPRIDVLVNNAGLHAFEQRVTSDGLAEMMAVNYLAPWLLTNTLL 124

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE--NYDASAAYSQSKLANLLFAREL 200
                 +              H   ++     ++SE  + ++SA Y ++KL N++F  EL
Sbjct: 125 QSLIASRNARIVNVASEASRNHGELKLPGDLTDISEFTSRESSAIYGKTKLLNIMFTAEL 184

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAA 260
            RRL GTG+   A++PG   T + R +    ++ R  I   F   +  P  G   ++  +
Sbjct: 185 ARRLSGTGIIVNALNPGFNVTGLGRELWFATALER--ILKFF--HIGDPRKGADIILRLS 240

Query: 261 LDPKLKDCAGDYY--VDMKKAEPSQEAQDFELAQWLWRVSEAWTK 303
           +D +     G Y+  +      P     D  +   LW  +E   K
Sbjct: 241 IDAQYNSVTGGYFNVITGNPISPIYPGGDKVMQNKLWSDTETLLK 285


>UniRef50_A0BGD0 Cluster: Chromosome undetermined scaffold_106,
           whole genome shotgun sequence; n=2; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_106,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 315

 Score = 89.4 bits (212), Expect = 1e-16
 Identities = 71/256 (27%), Positives = 101/256 (39%), Gaps = 18/256 (7%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           ++TI+ITGA  GIG   AK  +K    + +A R++++ + Q  +    TN +Y+Y    D
Sbjct: 45  DKTILITGATDGIGWETAKKLSK-AKSIIVAGRNIERIKSQLNNY---TNIQYMYL---D 97

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           L     +++F   FK     L +L+NNAGV    +  TK GFE   G+            
Sbjct: 98  LNDLDKVQQFCEEFKKSYGKLDILINNAGVFNLDQKYTKQGFEQNFGINYLSPFLLTYNL 157

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDA-----SAAYSQSKLANLLFARE 199
                              H      + D N   N D         Y  SKLAN+  A  
Sbjct: 158 LGHIPNEQESRIIFVASRAH-TDTPRQVDFNYYLNQDPIPYPWHKTYGISKLANMYEASS 216

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
               L GT +   ++ PG+V T++             F+ P  W F K PE G  T    
Sbjct: 217 FANHLKGTNIKVYSLHPGVVRTNMLNQFQFYS-----FLAPFIWYFTKTPEQGSVTSKFL 271

Query: 260 ALDPKLKDCAGDYYVD 275
           A  P      G YY D
Sbjct: 272 ATSPNNNLKNGYYYKD 287


>UniRef50_A2R494 Cluster: Contig An14c0200, complete genome; n=1;
           Aspergillus niger|Rep: Contig An14c0200, complete genome
           - Aspergillus niger
          Length = 319

 Score = 89.4 bits (212), Expect = 1e-16
 Identities = 78/288 (27%), Positives = 120/288 (41%), Gaps = 19/288 (6%)

Query: 28  IIITGANSG-IGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           ++ITG   G +G  AA   ++   A + +A R+++  +     I  ET +        DL
Sbjct: 26  VLITGVTLGSVGGEAALQLSRHAPALLVLAGRNLETLQATENAIKAETPDANTRLLIIDL 85

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGV-XXXXXXXXXXXX 144
           +S  S+R   A        L  L+NNAG+M  P   T +G E Q G+             
Sbjct: 86  SSQESVRRAAAEVNNYPERLDHLINNAGIMAAPYSTTPEGVELQFGINHIGHFLFTNLLL 145

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN--YDASAAYSQSKLANLLFARELGR 202
                              H+RG +   D+N      YD   AY QSK AN+LF+  L  
Sbjct: 146 EKIMSGESKVRVVNVSSAGHKRGPVRFGDVNFENGKCYDKWQAYGQSKTANMLFSVSLAE 205

Query: 203 RLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIY---------PLFWPFMKKPEIGG 253
           +    GV + ++ PG  +T I RH+   + V   + +          L W   +    G 
Sbjct: 206 KAGNKGVESFSLYPGRRETGIGRHLKPEEWVKAGWKHEDGSINDDPKLNW---RTASQGA 262

Query: 254 QTVVHAALDPKLKDCAGDYYVD--MKKAEPSQEAQDFELAQWLWRVSE 299
            T++ AA DP   D  G Y V+  +   E  + A D + A+ LW++SE
Sbjct: 263 ATLIVAAYDPSNSDKNGSYMVNNQVNNDEAVEYALDPKNAERLWKLSE 310


>UniRef50_Q26ER7 Cluster: Dehydrogenase/reductase; n=13;
           Bacteria|Rep: Dehydrogenase/reductase - Flavobacteria
           bacterium BBFL7
          Length = 334

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 83/288 (28%), Positives = 119/288 (41%), Gaps = 16/288 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKY-VYCRPCD 84
           +T +ITG  SG G  AAK    + AKV M  R+  K ++       E  N   V     D
Sbjct: 40  KTYVITGTTSGTGLEAAKILLAKDAKVVMLNRNNTKAQDTIAKFKSELGNHIEVSNIQMD 99

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGV-TKDGFETQLGVXXXXXXXXXXX 143
           LA  AS+R+   +     PH+  L+ NA + + PK V T DGFE+QLGV           
Sbjct: 100 LAQLASVRKAAKQVLSTIPHIDALICNAAIAQVPKQVLTVDGFESQLGVNHYGNFLLQGL 159

Query: 144 XX-XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR 202
                 K                   I   D+N   +Y+ +  YSQSKLA ++   EL  
Sbjct: 160 LFPLIDKSNGRIVTVGSEGYKMGIKTIKFDDMNWDNDYNPNTVYSQSKLAQIMSVYELQD 219

Query: 203 RLLGTG---VATIAVDPGLVDTDITRHMSMMKSVTRFFIYPL-FWPFMKKPEIGGQTVVH 258
           RL   G   V   A  PG   T + +    +  +TRF    +   PF++  E G    + 
Sbjct: 220 RLKNAGKSNVKVYACHPGASRTSLIKTSGSL--MTRFIWQMMKLSPFVQSAEKGSYPALM 277

Query: 259 AALDPKLKD------CAGDYYV-DMKKAEPSQEAQDFELAQWLWRVSE 299
            A +P+L         +G+Y+   + +      A+D      LW VSE
Sbjct: 278 CATEPELDQKRYYGPTSGNYWKGPVGECNLEPHAKDKATMVKLWEVSE 325


>UniRef50_A4RWK8 Cluster: Predicted protein; n=1; Ostreococcus
           lucimarinus CCE9901|Rep: Predicted protein -
           Ostreococcus lucimarinus CCE9901
          Length = 206

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 63/205 (30%), Positives = 90/205 (43%), Gaps = 6/205 (2%)

Query: 28  IIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETN-NKYVYCRP--CD 84
           ++ITGANSG+G  AAK  A +G  V +ACR V K E+  R++  +   N  V   P   +
Sbjct: 1   VLITGANSGVGYTAAKQIAAQGKTVVIACRSVHKAEQAARELKEDVGANAKVVTLPVGLE 60

Query: 85  LASTASIREFVARF-KGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           L   AS+RE+   F    +  L  LV NAG+M  P   T  G E   G+           
Sbjct: 61  LTDLASVREYALAFLDRSDLALEALVCNAGIMAAPLERTTQGHELHFGINHLGHFLLADA 120

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRG-RIHKQDLNMS-ENYDASAAYSQSKLANLLFARELG 201
                +                    +   DL+ +   YD   AY  SK  N+LFA E  
Sbjct: 121 LTPALRETKGRVVSVSSLLSMIGDFALDLDDLDWNRREYDPWYAYGASKAQNVLFADEFA 180

Query: 202 RRLLGTGVATIAVDPGLVDTDITRH 226
           RR    G+   ++ PG+V T++ R+
Sbjct: 181 RREGKNGIVANSLHPGIVTTNLVRY 205


>UniRef50_A1CLH8 Cluster: Short-chain dehydrogenase; n=2;
           Fungi/Metazoa group|Rep: Short-chain dehydrogenase -
           Aspergillus clavatus
          Length = 315

 Score = 89.0 bits (211), Expect = 1e-16
 Identities = 57/208 (27%), Positives = 90/208 (43%), Gaps = 8/208 (3%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           +++ ++ITG +SGIG    +  A  GA V+   R+++K +E     VLET    V     
Sbjct: 48  EDKVVLITGVSSGIGVETVRAMAVTGATVYGTARNIEKAKEALGS-VLETGR--VRLLHM 104

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXX---- 139
           D    AS++     F+ +   L+V++NNA VM  P+  TKDGFE Q G            
Sbjct: 105 DQTDLASVQACATTFRNQSSRLNVIINNAAVMNTPEDRTKDGFELQFGTNHLSHFALFWH 164

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                                   H+ G +   ++N   NY+   AY  SK AN+    +
Sbjct: 165 LQDLLLQSSTPSFHSRVVSVASAAHRYGPVQLDNINFEGNYNGWLAYGSSKTANIYMTTQ 224

Query: 200 LGRRLLGTGVATIAVDPG-LVDTDITRH 226
           + R     G+   +V PG  V  ++ +H
Sbjct: 225 IERLYGSRGLRGYSVHPGAFVSPNLQKH 252


>UniRef50_A1SQ46 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Nocardioides sp. JS614|Rep: Short-chain
           dehydrogenase/reductase SDR - Nocardioides sp. (strain
           BAA-499 / JS614)
          Length = 316

 Score = 88.6 bits (210), Expect = 2e-16
 Identities = 67/205 (32%), Positives = 89/205 (43%), Gaps = 6/205 (2%)

Query: 24  DNRTIIITGAN-SGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRP 82
           D RT+++TG    G+G+  A + A+RGA+V +A R  ++ EE R  I  E     +    
Sbjct: 20  DGRTVLVTGTTVGGLGQFTALELARRGARVVLAGRTEQRLEETRAAITTEVPAAALETLV 79

Query: 83  CDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX 142
            DLA  AS+R    +  G  P + VLVNNAGVM  P   T DG E QL            
Sbjct: 80  VDLADLASVRRAAVQAAGLGP-IDVLVNNAGVMGTPYHRTGDGLELQLATNHFGPFLLTG 138

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN--YDASAAYSQSKLANLLFAREL 200
                                H+  R    D   S++  Y     Y++SKLANLLF  EL
Sbjct: 139 LLLPQLVASGAGTVVTVSSQMHRVARSAPLDDPRSQHGRYQRWPTYARSKLANLLFTYEL 198

Query: 201 GRRL--LGTGVATIAVDPGLVDTDI 223
            RR       V  +A  PG   T +
Sbjct: 199 DRRARRAELPVRALAAHPGFAATHL 223


>UniRef50_Q7NKQ4 Cluster: Glr1423 protein; n=9; Bacteria|Rep:
           Glr1423 protein - Gloeobacter violaceus
          Length = 321

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 64/210 (30%), Positives = 86/210 (40%), Gaps = 4/210 (1%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIV-LETNNKYVY 79
           +    +  +ITGA+SGIG   A+     GA V  A R++ K E     +    +    + 
Sbjct: 18  IELKGKRFLITGASSGIGLETARSLVSHGASVVGAVRNLAKAEPATASVRDAASQGGSLE 77

Query: 80  CRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXX 139
               DLAS  S+R    +   +      ++ NAGVM  P G T DGFE Q G        
Sbjct: 78  LINLDLASLQSVRACADKLLADGQPFDAIIANAGVMATPFGRTIDGFEVQFGTNHLGHFA 137

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-YDASAAYSQSKLANLLFAR 198
                                   H+   I   D N  +  YD   AYS+SK AN LFA 
Sbjct: 138 LINQIEPL--LANDGRLVVLSSLAHRGADIDLDDPNFEQQAYDPWVAYSRSKTANSLFAV 195

Query: 199 ELGRRLLGTGVATIAVDPGLVDTDITRHMS 228
           E  RR    G+   +V PG   TD+ RH+S
Sbjct: 196 EFDRRYRDRGIRAASVMPGNSLTDLPRHLS 225


>UniRef50_A3VMM7 Cluster: Dehydrogenase; n=1; Rhodobacterales
           bacterium HTCC2654|Rep: Dehydrogenase - Rhodobacterales
           bacterium HTCC2654
          Length = 302

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 80/291 (27%), Positives = 121/291 (41%), Gaps = 15/291 (5%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           D +  ++TG  SG+  A     A+ GA V MA R V++ E     I  E     +  R  
Sbjct: 5   DGQVAMVTGT-SGLCTAIVAGLARAGAHVIMAGRSVERGEAVLDTIRAEVPGAKLSFRQV 63

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVM-EPPKGVTKDGFETQLGVXXXXXXXXXX 142
           DLA  AS++ F A+   E   L +L+ NA VM E  +  TKDGFE   GV          
Sbjct: 64  DLADMASVKAFTAKTLAELDQLDILICNAAVMAELGRSETKDGFEMMFGVNHLAHFAMVV 123

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR 202
                                H+ G     DL     +    AY ++KLA L+FA+EL R
Sbjct: 124 GLLPLL-SRSNARVVALSSGAHKYGEFDFDDLQTKGKFKPMVAYGKTKLACLMFAKELQR 182

Query: 203 R--LLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKK-PEIGGQTVVHA 259
           R    G G+ ++A  PG   +           +  + +     PF+ + PE   + +++A
Sbjct: 183 RSEAQGWGITSVAAHPGFSRSQGVYDRLATIPIMGWIVGTFIIPFISQVPEKASEAILYA 242

Query: 260 ALDPKLKDCAGDY-YVDMKK-------AEPSQEAQDFELAQWLWRVSEAWT 302
           A    +    G+Y  V  ++       A  +  A+  ++A  LW VSE  T
Sbjct: 243 ATADDVTG-GGNYGPVGFRELVGPVGVASTADYAEREDIAARLWAVSEDLT 292


>UniRef50_Q9LFS7 Cluster: Putative uncharacterized protein F1N13_80;
           n=1; Arabidopsis thaliana|Rep: Putative uncharacterized
           protein F1N13_80 - Arabidopsis thaliana (Mouse-ear
           cress)
          Length = 346

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 80/291 (27%), Positives = 123/291 (42%), Gaps = 24/291 (8%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAST 88
           +ITGA SG+GKA A   A++G  V +  R  +   E  ++I  +  +  +     D++S 
Sbjct: 45  VITGATSGLGKATAFALAEKGFYVVLVGRSSQLLSETLKEIKNKNKDAQLKSFEADMSSF 104

Query: 89  ASIREFVARFK------GEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX 142
            SI  F    +         P + VLVNNAG++      T DG++  +            
Sbjct: 105 ESIFTFKNSLEQWLSDSALHPSIQVLVNNAGILATSSRPTIDGYDRMIATNYVGPFFLTK 164

Query: 143 XXXXXXKXXXX-XXXXXXXXXXHQRGRIHKQD--------LNMSENYDASAAYSQSKLAN 193
                 K               H    I K D         + S  Y  +  Y  SKL  
Sbjct: 165 LLLPLLKNSNVPSRVVNVTSFTHHSAFIQKLDKDSVTGVCFSTSNQYPCARIYEYSKLCL 224

Query: 194 LLFARELGRRLL----GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKP 249
           LLF+ EL R+L      + V+ IA DPG V T+I R +    +   F  + +    ++ P
Sbjct: 225 LLFSYELHRQLRLIDDSSHVSVIAADPGFVKTNIMRELPCYITSMVFLGFKIL-GLLQSP 283

Query: 250 EIGGQTVVHAALDPKLKDCAGDYYVDMK--KAEPSQEAQDFELAQWLWRVS 298
           E G ++++ AAL     + +G YY   K    E SQ ++D +LA+ LW  S
Sbjct: 284 EDGAESIIDAAL--STPETSGAYYFGGKGRTIESSQVSRDPKLAKQLWETS 332


>UniRef50_Q5V6R4 Cluster: Oxidoreductase; n=3; cellular
           organisms|Rep: Oxidoreductase - Haloarcula marismortui
           (Halobacterium marismortui)
          Length = 309

 Score = 88.2 bits (209), Expect = 2e-16
 Identities = 75/276 (27%), Positives = 116/276 (42%), Gaps = 13/276 (4%)

Query: 28  IIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCR--PCDL 85
           +++TG+ SGIG+ AA    + GA V +  RD     +    +V E +   V       D 
Sbjct: 21  VLVTGSTSGIGREAALSLGRLGADVIVHGRDA----DAGAAVVSELSGLGVDAAFVQADF 76

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A+   +R   A  + E   L +LVNNAG +     +T  G E    V             
Sbjct: 77  AAVDEVRSLAATVRDETDGLDILVNNAGGLFRQGRLTDIGVEYTFHVNHLAPYLLTTELL 136

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
                             H+   +    +   ++Y  + AYS SKLAN+LFA EL RRL 
Sbjct: 137 DHLNAGARVVTTASSA--HRGTSLDLDRVTTVDSYTGTWAYSHSKLANVLFATELARRLE 194

Query: 206 GTG--VATIAVDPGLV-DTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
            TG  V +  + PG +  +  +R +     + +F       P +   E G   ++H A+ 
Sbjct: 195 TTGRDVVSNCLHPGAIPGSGFSRFLP--GPIPQFVKLFDAVPGITSVEDGAAEILHLAVS 252

Query: 263 PKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
            ++ D +G Y+   + A PS  A+D   A  LWR S
Sbjct: 253 SRIGDVSGRYFAGQRPATPSHAARDRAAASRLWRRS 288


>UniRef50_Q3W5P1 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 241

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 61/202 (30%), Positives = 87/202 (43%), Gaps = 7/202 (3%)

Query: 19  RSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYV 78
           + V  + R  I+TGA+SGIG   A+  A  GA+V +A R+ +       DI+  T NK +
Sbjct: 33  QGVDLEGRRAIVTGASSGIGVETARALADAGAEVTLAVRNTEAGGRVADDIIAGTGNKAI 92

Query: 79  YCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPK-GVTKDGFETQLGVXXXXX 137
           +    DLA  AS+   V  + G    LH+LVNN GVM  P+   T +G+E          
Sbjct: 93  FVSKLDLADRASVTGLVEAWNGP---LHILVNNGGVMALPQLQRTPEGWEQHFATSHLGH 149

Query: 138 XXXXXXXXXXXKXXXXXXXXXXXXXXHQRGR--IHKQDLNMS-ENYDASAAYSQSKLANL 194
                                     H      +   D+     +Y    AY+QSK AN+
Sbjct: 150 FALALGLRDALAAAGSSRVVSVSSDGHVHANAPVDFDDIRFERRDYSGHRAYAQSKTANI 209

Query: 195 LFARELGRRLLGTGVATIAVDP 216
           LFA E  +R    G+A  A+ P
Sbjct: 210 LFAVEGAKRWAKDGIAVNALHP 231


>UniRef50_A6WAZ3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=7; Actinomycetales|Rep: Short-chain
           dehydrogenase/reductase SDR - Kineococcus radiotolerans
           SRS30216
          Length = 326

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 63/201 (31%), Positives = 87/201 (43%), Gaps = 4/201 (1%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R  ++TGA+ G+G A A   A  GA + +  R+  K       I        V     DL
Sbjct: 16  RHAVVTGASDGVGLALATRLAAAGADLTLPVRNQVKGRAALAAIRRAVPGARVVMADLDL 75

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPP-KGVTKDGFETQLGVXXXXXXXXXXXX 144
           +S AS+  F AR + E   +H+LVNNAGVM PP +  T DGFE Q G             
Sbjct: 76  SSLASVAAFGARMQEEGKAIHLLVNNAGVMTPPQRQSTVDGFELQFGTNHLGHVALVAHL 135

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR-- 202
               +               + GR++ +D N  + Y    AYS S +A  LF  EL R  
Sbjct: 136 LPLLRAGRARVTSQVSVAA-RSGRVNFEDPNWRDAYHGMKAYSSSMIAFGLFGLELERRS 194

Query: 203 RLLGTGVATIAVDPGLVDTDI 223
           R  G G+ +    PG+  T +
Sbjct: 195 RAQGWGITSNLSHPGIAPTSL 215


>UniRef50_Q0UI12 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 307

 Score = 87.8 bits (208), Expect = 3e-16
 Identities = 77/290 (26%), Positives = 120/290 (41%), Gaps = 16/290 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAK-RGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           + I++TG NSG+G+ +    AK R  K+++A RD+ K       I        V    CD
Sbjct: 18  KVILVTGGNSGLGRESILALAKQRPGKIYLAARDISKGSWASDLIKKHVPEAPVTVLECD 77

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           L+S +S+R    +   E   L +L+ NAGV+  PKG+++DG+E Q               
Sbjct: 78  LSSLSSVRNAARKVASESSRLDILMCNAGVVACPKGLSEDGYEIQFATNHLGHALLIKLL 137

Query: 145 XXXXKXXX-------XXXXXXXXXXXHQRGRIHKQDLNMSENYDASA---AYSQSKLANL 194
               +                       +G I    L+  ++         Y QSKLAN+
Sbjct: 138 LQMLRKTAKLHGNARIVSLTSPGFGFSPKGGIQFNSLHSEQDLGFGGPPKRYGQSKLANI 197

Query: 195 LFARELGRRLLGTGVATIAVDPGLVDTDI-TRHMSMMKSVTRFFIYPLFWPFMKKPEIGG 253
           L+A EL RR     +  +++DPG   T++ T    +MK+      + +    M   E G 
Sbjct: 198 LYADELSRR--NPQLTCVSIDPGAAKTELFTNQGWLMKTFITITTW-MRGEMMWSAEEGA 254

Query: 254 QTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTK 303
              + AA    +      Y    K  EP+   +D EL Q LW  +E   K
Sbjct: 255 YNQLWAA-TADIPINGALYKPIGKHFEPTGHLKDAELRQMLWDWTEGELK 303


>UniRef50_Q98K50 Cluster: Mlr1637 protein; n=2; Proteobacteria|Rep:
           Mlr1637 protein - Rhizobium loti (Mesorhizobium loti)
          Length = 279

 Score = 87.4 bits (207), Expect = 4e-16
 Identities = 71/277 (25%), Positives = 114/277 (41%), Gaps = 21/277 (7%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           ++TI+ITG+  G+G+  A+     GA+V +  RD  + +    +I         +    D
Sbjct: 5   DKTILITGSTDGVGRVVAQRLGADGARVLVHGRDAARGKAAVAEIEAAGGRAEFFA--AD 62

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGV--MEPPKGVTKDGFETQLGVXXXXXXXXXX 142
           LAS A IR      +     L +L+NNAG+      + V+ DG+E +  V          
Sbjct: 63  LASLAEIRHLAEAVRARTNRLDILINNAGIGTAAAKRQVSADGYELRFAVNYLAGFLLTS 122

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGR 202
                 K               Q   I   D+ ++  Y    AY QSKLA +LF  +L  
Sbjct: 123 ELLPLLKASAPARIVNVASAGQQA--IDFGDVMLTHGYSGVRAYCQSKLAQILFTVDLAE 180

Query: 203 RLLGTGVATIAVDP-GLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAAL 261
           +L GTGV   A+ P   ++T + R   +             W      E G + +V+ A 
Sbjct: 181 QLKGTGVTVNALHPASYMNTTMVRQAGVTP-----------W---SSVETGAEAIVNLAA 226

Query: 262 DPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
            P L+  +G Y+  +++A    +A D    Q L  +S
Sbjct: 227 SPALEGRSGLYFDGLREARADAQAYDATARQQLRSLS 263


>UniRef50_A2R1L8 Cluster: Contig An13c0060, complete genome; n=2;
           Aspergillus|Rep: Contig An13c0060, complete genome -
           Aspergillus niger
          Length = 332

 Score = 87.4 bits (207), Expect = 4e-16
 Identities = 60/206 (29%), Positives = 91/206 (44%), Gaps = 5/206 (2%)

Query: 25  NRTIIITGAN-SGIGKAAAKDFAKRGAK-VFMACRDVKKCEEQRRDIVLETNNKYVYCRP 82
           N+TI++TG +  G+G   AK  A      + +A RD+ K ++  ++I             
Sbjct: 23  NKTILVTGVSPGGLGAEFAKVIAIHSPSLIILASRDILKAQQTAQEIANIAPGVATRLLE 82

Query: 83  CDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGV-XXXXXXXXX 141
            DL S A +R         +  + VLVNNAGVM  P  +T+DG E+Q             
Sbjct: 83  LDLRSQAQVRNAAKEVLTYKEDIDVLVNNAGVMASPFSLTEDGIESQFATNHVGHFLFTN 142

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE--NYDASAAYSQSKLANLLFARE 199
                                 HQ   I   D N  E  NYD   AY QSK AN+LF+  
Sbjct: 143 LIIKKLVHPGTPCRVGNVSSNGHQLSSIRFHDWNFDEGKNYDPWLAYGQSKSANMLFSVS 202

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITR 225
           L ++L   G+ ++++ PG ++T++ R
Sbjct: 203 LAQKLGSKGLISVSLHPGTINTNLAR 228


>UniRef50_UPI0000D55E90 Cluster: PREDICTED: similar to CG11200-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG11200-PB, isoform B - Tribolium castaneum
          Length = 357

 Score = 87.0 bits (206), Expect = 6e-16
 Identities = 73/293 (24%), Positives = 127/293 (43%), Gaps = 16/293 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEE---QRRDIVLETNNKYVYCRP 82
           +  +ITG   GIG    K   +    V + CR+ +  E+   + RD  + T +  VY   
Sbjct: 66  KVAVITGGARGIGAEVVKMLLRCDIHVIIGCRNTQAGEQVLQKCRDSGVTTGDVTVY--K 123

Query: 83  CDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX 142
            D++   S++ F      + P ++ L+NNAG+M  P   ++DG+E+Q             
Sbjct: 124 LDISVLDSVKSFAKVVAEKHPKINYLINNAGIMFGPYIESRDGYESQFSTNYLGHFLLTH 183

Query: 143 XXX----XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAR 198
                                    H  G I  +D+N    Y +  AY+QSKLA +LF  
Sbjct: 184 LLLPQLCAAGTQNLKSRIVNVSSCAHLVGEIKFEDINNRHQYISGEAYAQSKLAQVLFTN 243

Query: 199 ELGR--RLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTV 256
            L    +     V   +V PG+V+T++    + +K++  +    +F    K PE G   +
Sbjct: 244 YLESVCKKENMPVQLHSVHPGIVNTELFDG-THLKNLAPWVPSLMF----KTPEQGAIPI 298

Query: 257 VHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLDEHKQ 309
           VHA L P L+   G Y  + +    S+ A+  +L + L+  ++   K+++  Q
Sbjct: 299 VHACLSPHLEGKGGTYIHNCRIFSTSENAKSEDLQEKLFNFTKDLLKIEDFGQ 351


>UniRef50_A0D206 Cluster: Chromosome undetermined scaffold_35, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_35,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 302

 Score = 87.0 bits (206), Expect = 6e-16
 Identities = 68/295 (23%), Positives = 124/295 (42%), Gaps = 8/295 (2%)

Query: 7   FNRDYYSGP-PYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQ 65
           F   Y  GP      +  + + +IITGA++GIGK  AK  A + A +  ACRD +K  + 
Sbjct: 5   FVHKYQRGPLRIYNQINLEGKIVIITGASAGIGKETAKRLAWQNATIVFACRDEQKTMKV 64

Query: 66  RRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDG 125
             +I   T N  ++     L    +++EFV  FK +   L +L+NNAG+ +      K+ 
Sbjct: 65  INEIKQVTGNSKLHYMNLQLDDYDNVKEFVKNFKSKFGVLDILINNAGIAQWWHKYNKNN 124

Query: 126 FETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAA 185
            E                                      R +++  D+ ++  Y  +  
Sbjct: 125 HELVFATNYLGHFLLTRLLIDSLSKESRIIIVSSVMHELIRSKLNFNDV-LNGKYLEN-- 181

Query: 186 YSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHM--SMMKSVTRFFIYPLFW 243
           Y+ +K   +L   +L + L  T V  +A+ PG++ T++      +++  + +  ++  F 
Sbjct: 182 YNNTKYCGVLLCLKLSQMLKNTKV--VALHPGVIKTELLDKAGNTILLQLIQKIMFWFFR 239

Query: 244 PFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           P     E G +T V+  L P  +   G YY   + ++ S+  +     + LW  S
Sbjct: 240 PMTLSVEEGAETTVYCTLMPYRELLTGGYYEKNRLSKHSKSIKKLNQVEELWEFS 294


>UniRef50_UPI000023E6D6 Cluster: hypothetical protein FG03303.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG03303.1 - Gibberella zeae PH-1
          Length = 306

 Score = 86.6 bits (205), Expect = 7e-16
 Identities = 64/228 (28%), Positives = 105/228 (46%), Gaps = 16/228 (7%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLE-TNNKYVYCR 81
           + + I+ITG NSG+G  + +   K   AK+F+ACR   K ++   ++  + +    V   
Sbjct: 16  NGKVILITGGNSGLGLESTRQLLKHDPAKIFLACRSKAKYDQAIAELQEQGSKTDAVSFL 75

Query: 82  PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX 141
             +LAS  SI+  V +F+ E   L VL+NNAG+M  P+G+T++G+E Q+G          
Sbjct: 76  SLNLASLESIKSAVRQFQQESTRLDVLLNNAGIMMTPEGLTEEGYEIQIGTNHMGHAFLT 135

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGRI--------HKQDLNMSENYDASAAYSQSKLAN 193
                  +                 G           +Q      N+  SA Y  SKLAN
Sbjct: 136 HLLLPVLEETTKINPDVRVICLASMGEAMAPKNPYQFEQFKTTMSNFSTSARYYISKLAN 195

Query: 194 LLFARELGRRLLGTGVATIAVDPGLVDTDIT----RHMSMMKSVTRFF 237
           + +A  L  R     +  I++ PG+V T++T     +  +M ++TR F
Sbjct: 196 VHYAAALAER--HPSLKIISIHPGIVQTNLTGPAVSNSLIMGTLTRLF 241


>UniRef50_Q9S1Q1 Cluster: Putative oxidoreductase; n=2;
           Streptomyces|Rep: Putative oxidoreductase - Streptomyces
           coelicolor
          Length = 311

 Score = 86.6 bits (205), Expect = 7e-16
 Identities = 56/202 (27%), Positives = 88/202 (43%), Gaps = 2/202 (0%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RT +ITG NSGIG   A+  A+ GA+V +A R   + ++    +   T          DL
Sbjct: 18  RTALITGGNSGIGLETARALARHGARVILAGRSRTRLDQAAEAVRAATPEARTDTLVLDL 77

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVME-PPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           +  +S+R+   R   E   + +L NN GVM  P +  T DG E  +G             
Sbjct: 78  SDLSSVRDAATRI-AETETVDLLFNNGGVMNLPERRTTHDGLEMTVGTNHLGHFAFNAQV 136

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
               +               +      +DL   ++Y A  AY++SK AN+++  EL RR 
Sbjct: 137 WPAVRRSPAPRVVTVSAIAARWPMGRLEDLMSEKSYRAMGAYAKSKRANIVYTLELARRT 196

Query: 205 LGTGVATIAVDPGLVDTDITRH 226
             + V  + V PG   T++ +H
Sbjct: 197 ASSPVEALVVHPGAAMTNLQQH 218


>UniRef50_Q7X507 Cluster: Oxidoreductase; n=1; Streptomyces sp.
           CH7|Rep: Oxidoreductase - Streptomyces sp. CH7
          Length = 244

 Score = 86.6 bits (205), Expect = 7e-16
 Identities = 68/234 (29%), Positives = 99/234 (42%), Gaps = 14/234 (5%)

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVME-PPKGVTKDGFETQLGVXXXXXXX 139
           R  DLAS AS+R F A+   + P + VLVNNAG++   P+  T DGFE  +G        
Sbjct: 8   RELDLASLASVRAFAAKLTADHPSVDVLVNNAGLVHLGPRRTTADGFELHVGTNMLGPYA 67

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                                   H+   +   DL     Y AS+AY +SKLA  LF  E
Sbjct: 68  LTGLLLDALTAGSGGRVVSLSSITHKNAHLDFGDLMSEHGYRASSAYGRSKLATTLFGLE 127

Query: 200 LGRRLLGTGVATIA--VDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVV 257
           L RRL   G+  ++    PGL  T++T      +      I        +  E G    +
Sbjct: 128 LDRRLRAAGLPVVSALAHPGLTRTNLTPRAWEHRGRFGRLIAAGGLLATQSVEQGALPQL 187

Query: 258 HAALDPKLKDCAGDYYVDMK---------KAEPSQEAQDFELAQWLWRVSEAWT 302
            AA DP+++   G ++   +         +A   +EA D  +A+ LW V+E  T
Sbjct: 188 RAATDPEVR--GGQFFGPARLWETRGPVTEARLGEEAADPAVARRLWAVAEDLT 239


>UniRef50_Q0UKX1 Cluster: Predicted protein; n=1; Phaeosphaeria
           nodorum|Rep: Predicted protein - Phaeosphaeria nodorum
           (Septoria nodorum)
          Length = 316

 Score = 86.6 bits (205), Expect = 7e-16
 Identities = 59/213 (27%), Positives = 91/213 (42%), Gaps = 11/213 (5%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLETNNKY-VYCR 81
           + + I++TG N+G+GK      A    A++++A R   K E    DI  +  N   +   
Sbjct: 15  EGKVILVTGGNAGLGKQTITYLAAHSPARIYLAARTASKAESAIADIKSQVPNACEIVHL 74

Query: 82  PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX 141
           P DL S +SI      FK  E  L +L+NNAG+M PP   TK+G+E Q G          
Sbjct: 75  PLDLTSFSSIASAADTFKSRESRLDILINNAGIMAPPYSTTKEGYEIQFGTNHMGHALLT 134

Query: 142 X----XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQ---DLNMSENYDASAAYSQSKLANL 194
                      K                R    +    D    EN +    Y  SKLAN+
Sbjct: 135 KLLLPTLLETAKQPGADVRIVSLSSAGHRMPASEGIVFDQAALENVNTWRRYGSSKLANI 194

Query: 195 LFARELGRRLLGTGVATIAVDPGLVDTDITRHM 227
           L+AR L        + ++++ PG++ TD+  ++
Sbjct: 195 LYARSLATHY--PQITSVSLHPGVILTDLFNNL 225


>UniRef50_UPI0000E49E46 Cluster: PREDICTED: similar to Retinol
           dehydrogenase 12, like; n=4; Strongylocentrotus
           purpuratus|Rep: PREDICTED: similar to Retinol
           dehydrogenase 12, like - Strongylocentrotus purpuratus
          Length = 535

 Score = 86.2 bits (204), Expect = 1e-15
 Identities = 43/122 (35%), Positives = 67/122 (54%), Gaps = 1/122 (0%)

Query: 11  YYSGPPYDRS-VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDI 69
           +Y G    +S V    +T+IITGAN+GIG+  A D A RGA+V M CR+  K +    ++
Sbjct: 50  FYGGTRRVKSRVSLKGKTVIITGANAGIGRETAVDLASRGARVIMGCRNPSKAQAALAEV 109

Query: 70  VLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQ 129
              +NN  V  +  D++   S+++F      EE  L +L+NNAG+       T +GF+  
Sbjct: 110 RKRSNNNDVIFKQVDVSDLKSVKDFAEEILREEERLDILINNAGIGGTKYSKTPEGFDMV 169

Query: 130 LG 131
           +G
Sbjct: 170 MG 171


>UniRef50_A5ESF8 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=3; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Bradyrhizobium sp. (strain BTAi1 / ATCC BAA-1182)
          Length = 274

 Score = 86.2 bits (204), Expect = 1e-15
 Identities = 80/282 (28%), Positives = 109/282 (38%), Gaps = 19/282 (6%)

Query: 27  TIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLA 86
           TIIITGA+ GIG AAA+     G  V +  R   K E   R++            P  LA
Sbjct: 3   TIIITGASDGIGAAAARQLKANGHNVVLVGRSKAKTEALARELNA----------PFHLA 52

Query: 87  STASIREFVARFKGE---EPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
               + + V R  GE      + VL NNAG +   + +T DGFE    V           
Sbjct: 53  DYTQLAD-VQRLAGELLDHGRIDVLANNAGGIMGQRALTSDGFEMTFQVNHLAPFLLTRL 111

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGR-IHKQDLNMSENYDASAAYSQSKLANLLFARELGR 202
                               +  GR     DLN    Y    AY   KL N+LF REL R
Sbjct: 112 LLERLIASRAKVIQTASAAANIFGRNFDVDDLNNERGYTPQGAYGYGKLENILFTRELDR 171

Query: 203 RLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
           R    G+A ++  PG+V ++     + +  +  F+  PL +     PE   Q +   A  
Sbjct: 172 RHRADGIAAVSFHPGIVRSNFANDTTHLMRL--FYHSPLKYLITISPERSAQRLTWLAES 229

Query: 263 PKLKDC-AGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTK 303
               D   G+ Y   +K  P     D   A+ LW  SE + K
Sbjct: 230 APGTDWQLGECY-SGRKPMPVAFKDDGTAARRLWEHSETFVK 270


>UniRef50_A4A816 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; unclassified Gammaproteobacteria|Rep: Short-chain
           dehydrogenase/reductase SDR - Congregibacter litoralis
           KT71
          Length = 470

 Score = 85.8 bits (203), Expect = 1e-15
 Identities = 69/278 (24%), Positives = 114/278 (41%), Gaps = 14/278 (5%)

Query: 1   MFVSFLFNRDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVK 60
           MF  + + R      P   S++     II+TGA SG+G A A+D A+RGA++ +  R+ +
Sbjct: 167 MFSKWGYRRGKKHWDPMSASLKGQR--IIVTGATSGLGLATARDLAERGAELILVMRNRE 224

Query: 61  KCEEQRRDIVLETNNKYVYCRPCDLASTASIREFVAR-FKGEEPHLHVLVNNAGVMEPPK 119
           + E   R++  ET N  +     DL+  A +     R  K  EP ++VLVNNAG +    
Sbjct: 225 RGEAVVRELKAETGNMAIRQELADLSIMADVDALADRLLKAGEP-INVLVNNAGALFNDW 283

Query: 120 GVTKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLN-MSE 178
           G T +G E    +                +                  ++    L  + +
Sbjct: 284 GTTPEGLEQSFALLLLSPWRLTRALKPLLQAAGDARVVNVVSGGMYSQKLRVDRLQAIPD 343

Query: 179 NYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDT-DITRHMSMMKSVTRFF 237
           NY  + AY++ K A  +   E        G+   A+ PG  DT  +   +    S+TRF 
Sbjct: 344 NYSGATAYARCKRALTVVTEEWAESWARDGIVVNAMHPGWADTPGVESSLPAFHSLTRF- 402

Query: 238 IYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVD 275
                   ++ PE G  T++  A   +     G  ++D
Sbjct: 403 -------ILRTPEEGADTIIWLAAASEAAKVTGKLFLD 433


>UniRef50_A1T3N3 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Mycobacterium vanbaalenii (strain DSM 7251 /
           PYR-1)
          Length = 328

 Score = 85.8 bits (203), Expect = 1e-15
 Identities = 72/254 (28%), Positives = 102/254 (40%), Gaps = 15/254 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R  I+T  + G+G    +  A  GA V +A R+ +        +      + V     DL
Sbjct: 30  RNAIVTAGHVGLGLETTRALADAGANVVVASRNPETAAAALVGV------ERVRVEQLDL 83

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
              ASI  FVA +   E  LH+L+NNAG+M         G+E Q                
Sbjct: 84  MDPASIERFVAGYG--EAALHILINNAGIMGGDLVRDARGYEAQFATNHLGHFQLTNGLL 141

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL 205
              +              H    I  +D +   +YD   AY QSK AN+LFA EL RR  
Sbjct: 142 PALRAADGARVVEVSSWGHHLSDIRWEDPHFESDYDGMVAYGQSKTANVLFAVELDRRWA 201

Query: 206 GTGVATIAVDP-GLVDTDITRHMSMMKSVTRFFI----YPLFWP--FMKKPEIGGQTVVH 258
             GV   ++ P G+V T++    ++        +     P+  P   MK P+ G  T V 
Sbjct: 202 DDGVRGYSLHPGGIVSTNLGPSFTLDDWRAMGLVDDGGQPIVDPDRDMKTPQQGASTQVF 261

Query: 259 AALDPKLKDCAGDY 272
           AA  P+L D  G Y
Sbjct: 262 AATSPQLADIGGVY 275


>UniRef50_A1DKR0 Cluster: Short-chain dehydrogenase; n=3;
           Trichocomaceae|Rep: Short-chain dehydrogenase -
           Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
           181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
           3700 / NRRL 181))
          Length = 311

 Score = 85.8 bits (203), Expect = 1e-15
 Identities = 74/293 (25%), Positives = 121/293 (41%), Gaps = 23/293 (7%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVL---ETNNKYVYCRP 82
           +  I+TG + G+GK   K      AK+++A R   K  E  R+I      +  + ++ R 
Sbjct: 24  KVFIVTGGSGGLGKELVKILYLHNAKIYVAARSEAKTREVIREIQRAHPSSTGELIFLR- 82

Query: 83  CDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKG-VTKDGFETQLGVXXXXX---- 137
             L    +I++    F  +E  L VL NNAGVM PP+G  T  G+E Q+G          
Sbjct: 83  LQLDDLTTIKQSAGEFLAKETRLDVLWNNAGVMVPPQGSKTVQGYELQIGTNNLGHFLFT 142

Query: 138 -----XXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLA 192
                                            R  I+  +++        + YS+SK  
Sbjct: 143 QFLRPVLVATAKTAPKNSVRVVWVSSSAADSAPRPAINFSNMDYHVEEGIWSKYSRSKAG 202

Query: 193 NLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIG 252
           N+L + E  RR  G G+ ++A++PG   T++ + M  M+         +F     +P  G
Sbjct: 203 NVLHSAEFARRTAGEGIISVALNPGNFVTNLQQSMPRMQ-------LAMFRLISHEPING 255

Query: 253 GQTVVHAALDPKL-KDCAGDYYVDMKKAEPS-QEAQDFELAQWLWRVSEAWTK 303
             T + A L P + ++  G +     K EP+ ++  D EL +  W  SE   K
Sbjct: 256 AYTELFAGLHPSITEENNGGWVSPFGKIEPARKDLLDPELGRQYWEWSETQVK 308


>UniRef50_Q41HA4 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Exiguobacterium sibiricum 255-15|Rep: Short-chain
           dehydrogenase/reductase SDR - Exiguobacterium sibiricum
           255-15
          Length = 290

 Score = 85.4 bits (202), Expect = 2e-15
 Identities = 75/291 (25%), Positives = 122/291 (41%), Gaps = 19/291 (6%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCE---EQRRDIVLETNNKYVYCRPCDL 85
           ++TGANSG+G    ++  +RG +V    R  KK     +  R+  +   N  V     D 
Sbjct: 5   VVTGANSGMGMVTIQELLERGDRVIATVRSQKKATLLIQLLREHAVSDANLEVEIVQLDQ 64

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
               S+R F          +  L+ NAG+M PP  VTKDGFE+Q  V             
Sbjct: 65  LD--SVRRFADVLFDRIGRIDRLILNAGIMVPPYHVTKDGFESQFQVNYLSHFYLIERLL 122

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLNM-------SENYDASAAYSQSKLANLLFAR 198
              +               + G I + D+ +        E Y+   +Y +SKL  ++  R
Sbjct: 123 PLIEQGHDPRVISISSLAGEGGMI-RTDIELEAIAHVRKEQYNPMKSYRESKLLQMVHMR 181

Query: 199 ELGRRLLGTGVATIAVDPGLVDTDI---TRHMSMMKSVTRFFIYPLFWP-FMKKPEIGGQ 254
           EL  +  GT    ++V PG+V+TD+    ++  ++K+V +      +W   +  PE G +
Sbjct: 182 ELAEQ-YGTLATFVSVHPGIVNTDLFYRGKYGKVLKTVLKPVAQVGYWTGKLYTPEYGAK 240

Query: 255 TVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLD 305
           T ++ A    + D  G YY D      +   +D    Q    +S+ W  LD
Sbjct: 241 TALYLATTDDVID-NGGYYADSAPRLSNPVVEDEAYRQQARALSKRWVGLD 290


>UniRef50_Q3VXB7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Prosthecochloris aestuarii DSM 271|Rep: Short-chain
           dehydrogenase/reductase SDR - Prosthecochloris aestuarii
           DSM 271
          Length = 297

 Score = 85.4 bits (202), Expect = 2e-15
 Identities = 70/271 (25%), Positives = 103/271 (38%), Gaps = 17/271 (6%)

Query: 30  ITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLASTA 89
           ITG+  GIG+AAA + A  G  V +  R  ++ E  RR+I  +T N  ++    D     
Sbjct: 36  ITGSTDGIGRAAAFELAAAGHTVVLHGRSFERLEHTRREIEEQTGNHSIHTVLADFTDLC 95

Query: 90  SIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXXXXK 149
            +R    + +     + +L+NNAGV  P   +T  G ET   V                 
Sbjct: 96  QVRRMADQLEKLCSVIDILINNAGVYMPRCQITTAGIETTFAVNHLAHFCLTTLLEPLLI 155

Query: 150 XXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLLGTGV 209
                         H  G      +     Y    AY+ SKL N+ F  E   RL  TGV
Sbjct: 156 ESRTRVVNVSSVDHHSAG-FSANSITGGTRYTGYQAYAFSKLCNVAFTLEHADRLRRTGV 214

Query: 210 ATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFM-KKPEIGGQTVVHAALDPKLKDC 268
               +DPG++ T +  H                W         G   +++ A   K+ D 
Sbjct: 215 TVNTLDPGILATKLL-HAG--------------WSLQGDDVSCGAPPLLYLACSSKVADI 259

Query: 269 AGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
            G Y+ +   A  S  A D E+ + LW +SE
Sbjct: 260 TGTYFENNHPAICSPIAHDPEIRRELWEISE 290


>UniRef50_A7HKH5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Fervidobacterium nodosum Rt17-B1|Rep: Short-chain
           dehydrogenase/reductase SDR - Fervidobacterium nodosum
           Rt17-B1
          Length = 340

 Score = 85.4 bits (202), Expect = 2e-15
 Identities = 80/286 (27%), Positives = 121/286 (42%), Gaps = 13/286 (4%)

Query: 16  PYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNN 75
           P   + R D + ++ITGA SGIG   AK +A  GA+V    R  +K E   RDI  E   
Sbjct: 35  PKQCTERCDGKVVVITGATSGIGYYTAKKYASMGARVITINRSKEKSEALVRDIEREFGV 94

Query: 76  KYVYCRPCDLASTASI---REFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGV 132
           K  Y    DL+S   I    EF++  K  EP + VL++NAGV    + +T DG ET   V
Sbjct: 95  KIEYFL-ADLSSLKDIYKAAEFLSCLK--EP-IDVLIHNAGVYLGKRTLTVDGLETNFVV 150

Query: 133 XXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRG--RIHKQDLNMSE-NYDASAAYSQS 189
                           K              ++     ++  DL   +  Y    AY  +
Sbjct: 151 HYLAPFIINYHLLEKYKEDKKGRIILVSSEGYRFAVWGLNLDDLQFEKARYTGLKAYGSA 210

Query: 190 KLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKP 249
           KLA +L        L    V   A+ PG+V T+  R  S   ++ R+F         + P
Sbjct: 211 KLAQILTMHIFADLLKPYNVTINAMHPGMVRTNTGRDNS---ALYRWFKKTFIDSISQTP 267

Query: 250 EIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
           EI  Q + +  +  ++++    ++   K  E +  A+D E A+ LW
Sbjct: 268 EISAQALYYLGVSKEVENITDKFFHLTKIEELAPPAKDMEEAKKLW 313


>UniRef50_A6N014 Cluster: Retinol dehydrogenase 11; n=8;
           Magnoliophyta|Rep: Retinol dehydrogenase 11 - Oryza
           sativa subsp. indica (Rice)
          Length = 198

 Score = 85.4 bits (202), Expect = 2e-15
 Identities = 50/132 (37%), Positives = 69/132 (52%), Gaps = 6/132 (4%)

Query: 174 LNMSENYDASAAYSQSKLANLLFARELGRRLL--GTGVATIAVDPGLVDTDITRHMSMMK 231
           LN  + YD   AY QSKLAN+L A+EL RRL   G  +    V PGL+ T++ RH   + 
Sbjct: 67  LNDEKTYDDKMAYGQSKLANILHAKELSRRLKEGGANITINCVHPGLIMTNLMRHSFFLM 126

Query: 232 SVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELA 291
            V +F  Y + W   K    G  T  +  L+P+LK   G Y+ D    + S+ A++  LA
Sbjct: 127 RVLQFATY-ILW---KSVPQGAATTCYVGLNPQLKGVTGQYFADCNVEKTSRFARNDALA 182

Query: 292 QWLWRVSEAWTK 303
           + LW  SE   K
Sbjct: 183 KQLWEFSEKLIK 194


>UniRef50_A2ZC46 Cluster: Putative uncharacterized protein; n=1;
           Oryza sativa (indica cultivar-group)|Rep: Putative
           uncharacterized protein - Oryza sativa subsp. indica
           (Rice)
          Length = 576

 Score = 85.4 bits (202), Expect = 2e-15
 Identities = 42/109 (38%), Positives = 64/109 (58%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYC 80
           V A   T+++TGA +GIGK  A+  A RGA+V +  R ++   + ++ +  E  +  ++ 
Sbjct: 31  VDASRLTVVVTGATNGIGKETARVLALRGAEVILPARTLESGMKVKQSLAEEIPSSKLHV 90

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQ 129
              DL+S  S+R F   F     HL+VL+NNAGVM  P G++KDG E Q
Sbjct: 91  MEMDLSSLDSVRSFAKSFNSSYRHLNVLINNAGVMSCPFGLSKDGIELQ 139



 Score = 56.4 bits (130), Expect = 9e-07
 Identities = 28/69 (40%), Positives = 39/69 (56%)

Query: 238 IYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRV 297
           I+ +  PF+K    G  T  + AL P LKD +G Y+ D  +A P+  A+D ELA+ LW  
Sbjct: 171 IFSVMKPFLKSIPQGAATSCYLALHPGLKDVSGKYFADCNEATPTAVARDAELAKKLWEF 230

Query: 298 SEAWTKLDE 306
           SE  T  D+
Sbjct: 231 SEELTSGDQ 239


>UniRef50_UPI000023F261 Cluster: hypothetical protein FG04592.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG04592.1 - Gibberella zeae PH-1
          Length = 349

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 77/296 (26%), Positives = 125/296 (42%), Gaps = 24/296 (8%)

Query: 22  RADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLET----NNKY 77
           + D +  ++TG N+GIG    K  A RGAKV++  R   + +   + ++ E         
Sbjct: 50  KLDGKVAVVTGGNAGIGYYTVKHLASRGAKVYLGARSESRAKAAIKRLLEENPLIPQENV 109

Query: 78  VYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXX 137
           V+ R  DLA+ + + +     + +E  L +LVNNAG+       T DGFE  + V     
Sbjct: 110 VWLR-LDLANQSQVVDAAVELQSKEQRLDILVNNAGIDPYDYIRTADGFEMTMAVKYTNP 168

Query: 138 XXXXXXXXXXXKXXXXXXXXXXXXXXHQ-RGRIHKQDLNMSENYDASA-----AYSQSKL 191
                                     +Q        D   S  ++ S       Y  +KL
Sbjct: 169 AAAAQEESDVRVITVSSSGEAYSSPTNQFTSPKDLDDPCASPGWENSCLGQAMRYGTTKL 228

Query: 192 ANLLFARELGRRL--LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKP 249
           AN+LFA EL RR+      + +++++PG V TD         +V  F + PL       P
Sbjct: 229 ANVLFASELQRRMDEEDANIISLSLNPGTVRTD------GAANVMPFMVRPLVRFLFTAP 282

Query: 250 EIGGQTVVHAALDPKLKDCAGDY---YVD--MKKAEPSQEAQDFELAQWLWRVSEA 300
           E G  T + AA   ++K+ +  +   Y+D   +   PS  A+D    + LW ++EA
Sbjct: 283 ERGADTSLFAATAEEIKENSERWKGRYLDGPGRIKVPSLRARDAVAGRNLWNITEA 338


>UniRef50_Q2TWW2 Cluster: Dehydrogenases with different
           specificities; n=2; Trichocomaceae|Rep: Dehydrogenases
           with different specificities - Aspergillus oryzae
          Length = 323

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 73/286 (25%), Positives = 120/286 (41%), Gaps = 14/286 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAK-RGAKVFMACRDVKKCEEQRRDIVLE-TNNKYVYCRPC 83
           +  ++TG N+G+GK      AK R  ++++A R   K +     +    +NN  +   P 
Sbjct: 32  KVALVTGGNAGLGKETILQLAKHRPQRIYLAARSETKAQAAISSLKGSLSNNVEITWLPL 91

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX-- 141
           DL S  SI+     F  E   L +L+ NAGVM  P G T+ G E QLG            
Sbjct: 92  DLMSIKSIQTAAQTFNAESSRLDILILNAGVMSLPPGETEMGHEIQLGTNHTGHFLLTKL 151

Query: 142 ---XXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQ--DLNMSENYDASAAYSQSKLANLLF 196
                     +              H      +   D +  +  + +  Y  SK AN+LF
Sbjct: 152 LLPTLLKTAEEPNSDVRVVSLSSIGHNLAPSFETILDQDRLKKVNTNTRYGASKAANILF 211

Query: 197 ARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTV 256
           A EL RR     + +++V PG++ TD+   +S   ++       L     + P+ G    
Sbjct: 212 AAELARRY--PSITSVSVHPGIILTDLYSSVSDRSALAALGSKTLGLFGTQVPQ-GAYNE 268

Query: 257 VHAALDPKLKDCA-GDYYVDMKKAEP-SQEAQDFELAQWLWRVSEA 300
           + AA   K  D   G YY+ +   +P +Q A+  ++ + LW  +E+
Sbjct: 269 LWAAAGAKKHDLVNGSYYIPVGHLKPYNQYARSEDMGRRLWDWTES 314


>UniRef50_A6SHG0 Cluster: Putative uncharacterized protein; n=1;
           Botryotinia fuckeliana B05.10|Rep: Putative
           uncharacterized protein - Botryotinia fuckeliana B05.10
          Length = 266

 Score = 85.0 bits (201), Expect = 2e-15
 Identities = 55/208 (26%), Positives = 91/208 (43%), Gaps = 10/208 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           + I++TG N G+G       +K   + +++A R   K     ++I  +  +  +    CD
Sbjct: 25  KVILVTGGNVGLGFETILQLSKHNPSHIYLAARSEPKATAAIKEIQSKVPSAPITFIQCD 84

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX--- 141
           L S  S++E   +F  +E  L +L  NAG+M  P   T+ G+E Q G             
Sbjct: 85  LTSLPSVQECAKQFNAKESRLDLLFLNAGIMAVPAATTEQGYEVQFGTNHVGHALLTKLL 144

Query: 142 --XXXXXXXKXXXXXXXXXXXXXXHQR---GRIHKQDLNMSEN-YDASAAYSQSKLANLL 195
                    +              H     G I   DL    N Y  ++ Y QSKL+N+L
Sbjct: 145 LPTLLKTAEQKDADVRVISLSSLGHTMGPVGGIKFDDLKTDMNGYTTTSRYGQSKLSNIL 204

Query: 196 FARELGRRLLGTGVATIAVDPGLVDTDI 223
           FA+ L +R    G+  ++V PG+V+T++
Sbjct: 205 FAKGLNKRYGDKGITAVSVHPGVVNTNL 232


>UniRef50_Q82PZ7 Cluster: Putative dehydrogenase; n=2;
           Streptomyces|Rep: Putative dehydrogenase - Streptomyces
           avermitilis
          Length = 350

 Score = 83.0 bits (196), Expect = 9e-15
 Identities = 62/211 (29%), Positives = 87/211 (41%), Gaps = 8/211 (3%)

Query: 13  SGPPYD--RSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIV 70
           S PP++  R   AD R  ++TG N+GIG   A+  +  GA V +  R+  K E     I 
Sbjct: 40  STPPWNVQRLPGADGRVFLVTGGNAGIGYFVAEQLSATGATVVLGSRNPAKAEAATASIR 99

Query: 71  LETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVM--EPPKGVTKDGFET 128
                  V     DLA  +S+   V   + E   L  +V+NAGV   +PP+  T DG E 
Sbjct: 100 ARVPGSRVRAVRLDLADLSSLETAVESLEVE--RLDAVVHNAGVALDDPPREETGDGHEL 157

Query: 129 QLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQ 188
             G                                 +  R+   DL   ++Y     Y +
Sbjct: 158 MFGTNHLGHFALTQWLMPLLSAAPAARVVTMGSFAAKSERLDLDDLQSRKDYQPKRTYGR 217

Query: 189 SKLANLLFARELGRRL--LGTGVATIAVDPG 217
           SKLA + F  EL RRL   G+ VA++ V PG
Sbjct: 218 SKLAQMYFGVELDRRLRAAGSTVASVVVHPG 248


>UniRef50_Q3WC47 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=2; Bacteria|Rep: Short-chain dehydrogenase/reductase
           SDR - Frankia sp. EAN1pec
          Length = 467

 Score = 83.0 bits (196), Expect = 9e-15
 Identities = 43/95 (45%), Positives = 54/95 (56%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RT ++TGANSGIG  AAK  A+RGA V +ACR+  + E+    I        V+  P DL
Sbjct: 52  RTAVVTGANSGIGFEAAKALAERGATVVLACREPARAEQAAARIRAAAPRADVHVEPLDL 111

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKG 120
            S  S+R    R +   P L +LVNNAGVM P  G
Sbjct: 112 ISMTSVRAAAERIRAAHPRLDLLVNNAGVMLPSPG 146



 Score = 64.5 bits (150), Expect = 3e-09
 Identities = 41/91 (45%), Positives = 53/91 (58%), Gaps = 5/91 (5%)

Query: 186 YSQSKLANLLFARELGRRLLGTGVATIAV--DPGLVDTDITRH-MSMMKSVTRFFIYPLF 242
           Y  SKLANL+F  EL RRL  TG +TIAV   PG+  T +TR+ M   +      + PL 
Sbjct: 307 YPTSKLANLMFTFELQRRLAATGASTIAVAAHPGIARTGLTRNLMPPARVFMGQRLAPLM 366

Query: 243 WPFMKKPEIGGQTVVHAALDPKLKDCAGDYY 273
              +++PEIG    V AALDP +   AG+YY
Sbjct: 367 SWLVQEPEIGALATVRAALDPAVH--AGEYY 395


>UniRef50_A5B364 Cluster: Putative uncharacterized protein; n=1;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 300

 Score = 83.0 bits (196), Expect = 9e-15
 Identities = 58/183 (31%), Positives = 81/183 (44%), Gaps = 8/183 (4%)

Query: 32  GANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLASTASI 91
           GA SGIG   A+  AKRG +V +  RD+KK  E +  I  E+    V     DL+S ASI
Sbjct: 57  GATSGIGAETARVMAKRGVRVIIPARDLKKAGEMKERIQKESPKAEVIVLEIDLSSFASI 116

Query: 92  REFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFE-----TQLGVXXXXXXXXXXXXXX 146
           + F + F      LH+L+NNAG        ++D  E       LG               
Sbjct: 117 KRFCSEFLSLGLPLHILINNAGKFSHKLEFSEDKIEMSFATNYLGHFLLTELLIEKMVET 176

Query: 147 XXKXXXXXXXXXXXXXXH---QRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRR 203
             +              H   +R       +   +NY+ + AY+QSKLAN+L A+EL R+
Sbjct: 177 AAQTGIQGRIINVSSVIHSWVKRDGFRFNQMLNPKNYNGTRAYAQSKLANILHAKELARQ 236

Query: 204 LLG 206
           L G
Sbjct: 237 LKG 239



 Score = 33.1 bits (72), Expect = 9.7
 Identities = 17/49 (34%), Positives = 21/49 (42%)

Query: 252 GGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEA 300
           G  T  +  L  K +  +G YY D  +   S  A D   A  LWR S A
Sbjct: 239 GASTTCYVGLSRKTEGVSGKYYADCNECSCSSMANDESEAHNLWRQSRA 287


>UniRef50_A3LNL9 Cluster: Predicted protein; n=6;
           Saccharomycetales|Rep: Predicted protein - Pichia
           stipitis (Yeast)
          Length = 463

 Score = 83.0 bits (196), Expect = 9e-15
 Identities = 86/331 (25%), Positives = 133/331 (40%), Gaps = 28/331 (8%)

Query: 11  YYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKC--EEQRRD 68
           Y+SG           +  I+TGA +G+G   A + A RGA++ +  R  +     +   D
Sbjct: 39  YFSGASNTWERDLHGKVYILTGATTGMGAQVAYELATRGAQLVLLVRSTEDIWVVDYVED 98

Query: 69  IVLETNNKYVYCRPCDLASTASIREFVARFKGEEP--HLHVLVNNAGVMEP---PKGVTK 123
           +  +TNN  +Y   CDL S  S+R+F  ++   +P   L  +V  A    P   P+ VT 
Sbjct: 99  LRNKTNNVLIYAEECDLDSLYSVRKFATKWLDNQPPRRLDGVVCCAAESLPRGKPRQVTV 158

Query: 124 DGFETQLGVXXXXXXXXXXXXXXXXKX---XXXXXXXXXXXXXHQRGRIHKQDLNM-SEN 179
           DG E Q+GV                +                    G +   DL   S+ 
Sbjct: 159 DGVEQQMGVNYLANFHLLTLLGPSLRVQPPDRDVRVVLATCSSQALGEVDIDDLLWESKR 218

Query: 180 YDAS---AAYSQSKLANLLFARELGRRLLG--------TGVATIAVDPGLVDTDITRHMS 228
           Y +S     Y  SKL   +FA+E  RRL+           +    V+PG++ T  TR   
Sbjct: 219 YPSSQPWKIYGSSKLLLGMFAKEYQRRLMAYERNDKAPCNIRINLVNPGIMRTASTRRFL 278

Query: 229 MMKSVTRFFI----YPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPS-- 282
            M +V    +    YP+++ F+K    G Q V  A   P      G  +V   K  P   
Sbjct: 279 SMGTVLGLLLYLIMYPIWYLFLKSARSGAQNVFFALFAPIFPKLEGGNFVQECKINPKVR 338

Query: 283 QEAQDFELAQWLWRVSEAWTKLDEHKQAIAK 313
           QE  D +L + ++  +E      E + AI +
Sbjct: 339 QELTDADLQKEVFDKTEEIIVRLEKQSAIER 369


>UniRef50_UPI000049935F Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 311

 Score = 82.6 bits (195), Expect = 1e-14
 Identities = 67/273 (24%), Positives = 108/273 (39%), Gaps = 8/273 (2%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           ++ +++TG N GIG    +  AK  A +   CR  +        I  ET N  +    CD
Sbjct: 35  DKVVVVTGTNRGIGYETIRALAKLNATIVCCCRHEEAQIRVNMIIGKETKNNKLEFVKCD 94

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           L     +++       +   + +L+ NAG+M  P  ++K   E Q+              
Sbjct: 95  LMDLNCVKKAAQYIIDKYHKVDILITNAGIMCCPYTLSKQNIECQMATNHIAHAAFINYL 154

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDL-NMSENYDASAAYSQSKLANLLFARELGRR 203
               K              H        DL    E+Y  +  Y +SKLA  +F  +  + 
Sbjct: 155 IPALKESEKPRVVAVSSLAHLFTTNKSIDLIGKKEDYQRAFRYFESKLAVGMFIHQFAKE 214

Query: 204 LLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDP 263
                +  + V PGLV +++ R+         +F+ P F  F K PE   QT +H AL  
Sbjct: 215 --HPDIIAVHVHPGLVYSNLWRYWCPW---LMWFVSPFFKIFWKTPEEACQTTLHCALAD 269

Query: 264 KLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWR 296
            ++   G YY D K A+ +    D  L Q L++
Sbjct: 270 DIQ--TGAYYSDCKIAKHNPIIDDGILCQKLYK 300


>UniRef50_Q17CG7 Cluster: Short-chain dehydrogenase; n=2;
           Culicidae|Rep: Short-chain dehydrogenase - Aedes aegypti
           (Yellowfever mosquito)
          Length = 328

 Score = 82.6 bits (195), Expect = 1e-14
 Identities = 70/265 (26%), Positives = 111/265 (41%), Gaps = 8/265 (3%)

Query: 9   RDYYSGPPYDRSVRADNRT-IIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRR 67
           R +Y G  Y    +   R  I+ITGA SGIG A  ++ + R   + + CR +      R+
Sbjct: 21  RWFYIGRLYRNKRKFTGRELIVITGATSGIGLALVQELSSRNCHLVLGCRSLTSGILLRK 80

Query: 68  DIVLETNNKY-VYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGF 126
            +  ++     V     +L+S  S+  FV         ++ LVNNAG+     G+T DG 
Sbjct: 81  QLERQSGPDITVDIFELNLSSLKSVARFVDNVSNLRKPIYALVNNAGIFYARPGLTVDGI 140

Query: 127 ETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENY-DASA- 184
           E  L V                K                +      DL +   + D SA 
Sbjct: 141 EQTLQVNFLSQYLLTILLLPKLKQYPDNSRVIIVSSKAHQAIDRFPDLELHREFDDCSAN 200

Query: 185 ---AYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIY-P 240
              AY  SK + + FA +L   L  + V+   VDP  V+T+I R    + +   F++  P
Sbjct: 201 RFRAYQYSKFSLVTFAHKLSSILENSSVSVHCVDPENVETNIYRSFPPLSNKLLFYLQKP 260

Query: 241 LFWPFMKKPEIGGQTVVHAALDPKL 265
           L +  +K P  G Q +++A L P++
Sbjct: 261 LRFFLIKTPREGAQGLLYAILSPEV 285


>UniRef50_Q5D9J1 Cluster: SJCHGC09542 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC09542 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 338

 Score = 82.2 bits (194), Expect = 2e-14
 Identities = 73/261 (27%), Positives = 114/261 (43%), Gaps = 21/261 (8%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAST 88
           IITGANSGIG+A A + AKR  K+ + CR +    + + +I   T N  +  +  DL + 
Sbjct: 42  IITGANSGIGRATALELAKRKWKLTLGCRSMDSGIKVKNEITTVTGNHAISVKLLDLENP 101

Query: 89  ASIREFVARFKGEEPHLHVLVNNAG----VMEPP---KGVTKDGFETQLGVXXXXXXXXX 141
            +I+EFV   +     +H LVNNAG    ++ P    + +        +G          
Sbjct: 102 RTIKEFV---QSLSLPVHALVNNAGAFPNLLRPSMYFQDINVTLATNYVGHFYLTTLLLP 158

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDL----NMSENYDASAAYSQSKLANLLFA 197
                  +               ++G     DL      + +   S AYS SKLA  LF+
Sbjct: 159 YFRKSYLETSIYPRVIVVSSSLSRKGNFSTNDLFQPYTAASDLSPSKAYSDSKLACNLFS 218

Query: 198 RELGRRLLGTGVATI-----AVDPGLVDTDITRH-MSMMKSVTRFFIYPLFWPFMKKPEI 251
           REL RR  G+G   +         G+V+T++ ++ ++      +FFI  L W  +K P  
Sbjct: 219 RELHRR-YGSGENKLLDVYCLFTGGMVNTNLFQNTLTTYSPSIQFFIRGLMWLILKSPIE 277

Query: 252 GGQTVVHAALDPKLKDCAGDY 272
           G QTV+H      + +   DY
Sbjct: 278 GCQTVIHCTASNDVPNGHRDY 298


>UniRef50_A4VT50 Cluster: Dehydrogenase with different
           specificities; n=5; Streptococcus|Rep: Dehydrogenase
           with different specificities - Streptococcus suis
           (strain 05ZYH33)
          Length = 289

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 64/272 (23%), Positives = 113/272 (41%), Gaps = 5/272 (1%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +TI+ITG+  GIGK  A   A  G +V +  R+ +K      DI L+T +K ++    D 
Sbjct: 3   KTILITGSTDGIGKHLAMKLASEGHEVILHGRNSEKLRVALSDIQLKTGSKKIHGYLADF 62

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGV-MEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
           +  A +  F    K +   + VL+NNAG      +  T +  E    +            
Sbjct: 63  SKLADVYRFSQEIKRDFEQIDVLLNNAGAYFGDARVATAENIEMTFMLSVQVPYILTTEL 122

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRL 204
               +              H   +    D  + ++Y A+ AY+ +KL  +  A      L
Sbjct: 123 LPLLE-KAAGRVIHTSSLMHHFAQTRGLDFGLEQSYSAAMAYNNAKLYTIWLAIAQAEAL 181

Query: 205 --LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALD 262
              G+ V   A  PGL+ T++     + +++    +  L  PF K  + G +T  + +L 
Sbjct: 182 EKQGSSVTVNAYHPGLIATNLGND-GIKRNLRSRILTSLMKPFSKDLDQGIETGYYLSLS 240

Query: 263 PKLKDCAGDYYVDMKKAEPSQEAQDFELAQWL 294
           P++   +G Y+ + + A  S +  D   +Q L
Sbjct: 241 PEVAGVSGRYFAEKRLANVSLKGFDLAKSQAL 272


>UniRef50_A3LNP9 Cluster: Short-chain alcohol dehydrogenase; n=1;
           Pichia stipitis|Rep: Short-chain alcohol dehydrogenase -
           Pichia stipitis (Yeast)
          Length = 338

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 88/330 (26%), Positives = 140/330 (42%), Gaps = 36/330 (10%)

Query: 6   LFNRDYYSGPPY--DRSVRADNRTIIITGANSGIGKAAAKDFA-KRGAKVFMACRDVKKC 62
           + N  + S P Y  ++  + D + +I+TG N+G+G   AK  A    AKV++  R  +K 
Sbjct: 19  MINGYFPSNPSYTEEQYPKLDGKVVIVTGGNTGVGYQTAKSLAGSTNAKVYIFARSEEKA 78

Query: 63  EEQRRDIVLETNNKY------VYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVME 116
               R + LE   +Y      V+    DL    +I+     F  +E  L ++++NAGVM 
Sbjct: 79  LAAIRRMELEVAQEYNKSSINVHFIKLDLGDLTTIKASADEFLSKENRLDIVIHNAGVMG 138

Query: 117 PPKG-VTKDGFETQLGV----------XXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQ 165
              G  T  G E QLG                           +               +
Sbjct: 139 TSVGSKTVQGVELQLGTNCFGPHLLQKYFDPLVIETSKTNKPYESRIVWVASSAHFQSPE 198

Query: 166 RGRIHKQDLNMSEN-YDASAAYSQSKLANLLFARELGRRLLGTG-VATIAVDPGLVDTDI 223
           RG IH  D N  +  +     Y QSK  N++ A    +   G   V ++++ PG ++TDI
Sbjct: 199 RG-IHYADPNFVDTPHLPRVLYCQSKAVNIMQAIAWPKNHPGADRVLSVSLCPGFLNTDI 257

Query: 224 TRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQ 283
            RH S    + ++FI P  W  +  P  G  T ++AAL+P+LK+  G+YY    +     
Sbjct: 258 QRHAS---GIWKWFI-P--W-VLHDPRYGAYTELYAALNPELKN-QGEYYQSFGRL--GD 307

Query: 284 EAQDFELAQWLWRVSEAWTKLDEHKQAIAK 313
              D +L +    V +AW   +E  +A  K
Sbjct: 308 IRPDIKLEE---NVDKAWAYCEEQVKAYYK 334


>UniRef50_A2R9B8 Cluster: Contig An17c0030, complete genome; n=6;
           Pezizomycotina|Rep: Contig An17c0030, complete genome -
           Aspergillus niger
          Length = 311

 Score = 81.8 bits (193), Expect = 2e-14
 Identities = 77/286 (26%), Positives = 128/286 (44%), Gaps = 20/286 (6%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           +TI+ITGANSG+GK +  +F++   +++++A R++ K +    +I  +     ++    D
Sbjct: 15  KTILITGANSGLGKTSVLEFSRHNPSQIWLAARNLTKAQSAADEIKQQVPTARIHLLELD 74

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDG-FETQLGVXXXXXXXXXXX 143
           L+S ASI++ V  F      L +L+ NAGVM  P G+T DG +E Q G            
Sbjct: 75  LSSFASIQKAVEVFLSTATRLDILMLNAGVMAAPPGMTPDGRYEVQFGTNYMGHALLTRL 134

Query: 144 XXXXXKXXXXXXXX-------XXXXXXH-QR----GRIHKQDLNMS-ENYDASAAYSQSK 190
                +                     H QR    G +  +    + E+    A Y QSK
Sbjct: 135 LLPIMEKTAKRDDAGVGGRVRIVAVASHGQRYAPPGGLQFETFKTNGESMGPFARYGQSK 194

Query: 191 LANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRF-FIYPLFWPFMKKP 249
           LA +L+ R L +  L   +   ++DPG+V T +    +      +F F   L        
Sbjct: 195 LALVLWVRMLAQ--LYPWLTAASIDPGVVGTTLGDGATGAPRYIQFLFKVALVLRLAASL 252

Query: 250 EIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
           E G +  + AA+  ++   +G+YY  +     S   +D ELA+ LW
Sbjct: 253 ENGVRNQLWAAVSREVN--SGEYYDPVGVVGKSALGRDEELARRLW 296


>UniRef50_Q3WGZ8 Cluster: Short-chain dehydrogenase/reductase SDR;
            n=1; Frankia sp. EAN1pec|Rep: Short-chain
            dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 1085

 Score = 81.4 bits (192), Expect = 3e-14
 Identities = 72/296 (24%), Positives = 117/296 (39%), Gaps = 25/296 (8%)

Query: 15   PPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETN 74
            PPY     AD    ++TGA+SGIG+A A+  A++G +V    RD  +      +I     
Sbjct: 795  PPY-----ADRPVAVVTGASSGIGRATARTLAEQGWQVIGVGRDPVRSAATEAEIAAAAR 849

Query: 75   NK--YVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGV 132
                +   R  D    A +R      +   P L +L+NNAG +   + ++ +G E    V
Sbjct: 850  KDGGFTMLRG-DFTLMADVRRVAGEIQHLTPRLDILINNAGGVRDRQIISAEGTEATFAV 908

Query: 133  XXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHK-------QDLNMSENYDASAA 185
                            +                    H+        DL     +  + A
Sbjct: 909  NHLAPFLLTRELTPLLRASAASLPAGSTRVIAVSSSGHRAVDGLDWDDLQSLGEFRPAVA 968

Query: 186  YSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRH--MSMMKSVTRFFIYPLFW 243
            Y ++KLAN+LF REL RR    G+   A+ PG+V ++ + H   +M   +      P   
Sbjct: 969  YCRAKLANILFTRELARRAGPDGIVAQAMHPGVVASNFSAHGDAAMRAHMAAADTVP--- 1025

Query: 244  PFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
                 P+   +T+   A +P+     G Y+    +  P++ A+D   A  LW  SE
Sbjct: 1026 -----PDEPAETLAWLATEPEGGRTGGRYFHRRAEELPAEAARDDAAAARLWTESE 1076


>UniRef50_A5FBJ6 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=4; Bacteroidetes|Rep: Short-chain
           dehydrogenase/reductase SDR - Flavobacterium johnsoniae
           UW101
          Length = 331

 Score = 81.4 bits (192), Expect = 3e-14
 Identities = 61/202 (30%), Positives = 85/202 (42%), Gaps = 8/202 (3%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +T I+TG N+GIG    K  A  GA V +  RD +K    +R++    N   V     DL
Sbjct: 36  KTAIVTGGNTGIGMETVKTLAAAGAVVIVPARDAEKA---KRNLEGTAN---VIIEKMDL 89

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
               SI  F  +F      LH+L+NNAG+M  P      G+E+QL               
Sbjct: 90  MDPGSIDAFTEKFLLSGRTLHLLINNAGIMWVPLRRDSRGYESQLATNYLALFQLTARLW 149

Query: 146 XXXKXXXXXXXXXXXXXXHQRGRIHKQDLN-MSENYDASAAYSQSKLANLLFARELGRRL 204
              K              HQ      QD N ++  Y+    Y QSK A  LF+ EL  R 
Sbjct: 150 PALKKADGARVVNVSSGGHQFSDFDFQDPNFLNREYETLQGYGQSKTAVNLFSLELDNRA 209

Query: 205 LGTGVATIAVDPGLV-DTDITR 225
               V + ++ PG V +T++ R
Sbjct: 210 KKYNVRSYSLCPGAVGETELAR 231


>UniRef50_UPI0000D57168 Cluster: PREDICTED: similar to CG7675-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG7675-PB, isoform B - Tribolium castaneum
          Length = 291

 Score = 81.0 bits (191), Expect = 4e-14
 Identities = 65/289 (22%), Positives = 113/289 (39%), Gaps = 15/289 (5%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           +++++ITGAN G+G   A   A +  ++ MA  D       +  IV +T N  +  +  D
Sbjct: 9   SKSVLITGANEGLGFCTALALAAKNHRIIMA--DKADLALSKSKIVKKTGNCDIVTKFVD 66

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQL-----GVXXXXXXX 139
             S   +R        EE  L VL+NN GV    K  T DG +  +     G        
Sbjct: 67  FTSLTCVRNLAQEIVQEEEKLDVLINNVGVFCLGKERTVDGLQATMQVNHFGPFLLTHLL 126

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                                        ++  D++  + + +   Y  SKL N++ +  
Sbjct: 127 ADLLAKSAPSRVIFVSSLGAFFNNLTISNVNNPDVSYVDAFSSLLVYYNSKLCNMIVSNG 186

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
             +R     +   +V PG+     T  +   K V      P F  F++ PEIG +     
Sbjct: 187 FAQRFSKEEITFNSVHPGM---SATTFLWKNKPVAN----P-FQCFLQSPEIGAENCAFL 238

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWTKLDEHK 308
           A   ++ + +G ++VD ++ +  +   D E    +W +SE +  L E K
Sbjct: 239 ATSEQVANVSGKFFVDFREHQQPRVTTDAEFCSEIWAISEDFVGLTEEK 287


>UniRef50_Q9PA04 Cluster: Ketoreductase; n=7; cellular
           organisms|Rep: Ketoreductase - Xylella fastidiosa
          Length = 296

 Score = 81.0 bits (191), Expect = 4e-14
 Identities = 65/276 (23%), Positives = 112/276 (40%), Gaps = 9/276 (3%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + I++TGA+ GIGK  A   AK+G K+ +  R+ +K E    +I  ++ N  V     D 
Sbjct: 7   KVILVTGASDGIGKFTAATLAKQGHKLIIHGRNRQKTEAALAEIKRQSGNPDVAMFLADF 66

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGV-MEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
              A ++ F    K +  H+ VL+NNAG      + VT +G E  + +            
Sbjct: 67  LPLAGVKAFADAIKEKYDHIDVLINNAGAQFTEQREVTSEGHEKTMAINVFAPMLLTKLL 126

Query: 145 XXXXKXXXXXXXXXXXXXXHQ-RGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRR 203
                              H+  G+    D+ + + Y  + AYS SKL  +         
Sbjct: 127 MPLLVKSESARVVTVASDAHRMAGKPDLDDIELKQGYHMAKAYSLSKLYVIWVMHHFIGE 186

Query: 204 LLGTGVATIA---VDPGLVDTDITRH-MSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
               G+  +    V P    T++ R  +   K    FF++ +    M K      + ++A
Sbjct: 187 TKKAGIHNVTFNLVHPASTRTNLGREAVKSWKWKIIFFLWQIMLVSMDK---AASSTLYA 243

Query: 260 ALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
           A  P+L+  +G Y+    + +PS +    E  Q +W
Sbjct: 244 ATAPELEGVSGRYFGPKGEEQPSAKYHSPENEQKVW 279


>UniRef50_Q2UF38 Cluster: Dehydrogenases with different
           specificities; n=1; Aspergillus oryzae|Rep:
           Dehydrogenases with different specificities -
           Aspergillus oryzae
          Length = 307

 Score = 80.2 bits (189), Expect = 6e-14
 Identities = 82/288 (28%), Positives = 117/288 (40%), Gaps = 18/288 (6%)

Query: 27  TIIITGANSG-IGKAAAKDFAK-RGAKVFMACRDVKKCE---EQRRDIVLETNNKYVYCR 81
           + ++TGA+ G +G A A   A  R + + +  R   K        ++I  ET   +V+  
Sbjct: 16  SFVLTGASEGGLGGATALALASARPSHLVLLARTENKVRTVISTIKEISPETQPAFVHI- 74

Query: 82  PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX 141
             +L    S+R   A        + VL+NNAGVM  P   +K G E  L +         
Sbjct: 75  --ELEDLDSVRRAAADVLSLTSKIDVLINNAGVMAIPWSKSKSGLEKTLAINHIGHFLLT 132

Query: 142 XXXXXXXKXXX-XXXXXXXXXXXHQRGRIHKQDLNMSEN--YDASAAYSQSKLANLLFAR 198
                                  ++       D N S+   Y   AAY QSK AN+LF  
Sbjct: 133 KLLMPSILAAGPGSRIVNVTSAAYRMAPFFFDDWNFSDGQTYHPLAAYGQSKTANILFTV 192

Query: 199 ELGRRLLGTGVATIAVDPGLVD-TDITRH-----MSMMKSVTRFFIYPLFWPFMKKP-EI 251
            L +R    G+ + A  PG +  T +  H      S M  V R      F P   K  E 
Sbjct: 193 GLAQRYKEHGILSFAAHPGYIPGTSLLLHGPDLDPSAMDEVARKNTGFPFGPDPPKSLEQ 252

Query: 252 GGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
           G  T + AAL P+L D +G Y  D +  E  + A+D +LA  LW +SE
Sbjct: 253 GISTTLVAALSPELTDASGAYMEDCQVCEAREYARDPKLADRLWSLSE 300


>UniRef50_A4RXM2 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 342

 Score = 79.8 bits (188), Expect = 8e-14
 Identities = 76/290 (26%), Positives = 119/290 (41%), Gaps = 23/290 (7%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEE-----QRRDIVLETNNKYVYC 80
           +T ++TG  SGIG   A+   KRGA+V +ACR   K E       +    + T       
Sbjct: 44  KTCVVTGPTSGIGVTTARALVKRGARVVLACRTPSKAEALVERWTKEAAAVGTAPPDCAV 103

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGV--TKDGFETQLGVXXXXXX 138
              DL S AS+  F   F+  E  L VL+NNAG+ +       T DG E  L        
Sbjct: 104 MALDLDSLASVEAFAKAFQQREKRLDVLINNAGIFDMSGAYVRTSDGREQHLQANFLAPA 163

Query: 139 XXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE------NYDASAAYSQSKLA 192
                     +                +       LN+S+      +Y + AAY+ SKLA
Sbjct: 164 LLTMTLLNALRKTGAETGDARVVFVSSKLHELCTGLNLSDMDFKRSSYSSQAAYASSKLA 223

Query: 193 NLLFARELGRRL--LGTGVATIAVDPGLVDTDITRHMSM-MKSVTRFFIYPLFWPFMKKP 249
            +LF + L  RL     G   + + PG + T + R + M ++S+ +     LF   +   
Sbjct: 224 EVLFVKALDARLRAKAPGTRALVLHPGNIVTGVVRTLPMWLQSLYKI----LFERILLTA 279

Query: 250 EIGGQTVVHAALDPKLKDCA--GDYYV-DMKKAEPSQEAQDFELAQWLWR 296
           + G +  ++ A   +    A  G Y+  + ++  PS+ A     A+ LWR
Sbjct: 280 DQGARCSLYCATRTEAVASATIGPYFTSECEERTPSKYALVEGEAEKLWR 329


>UniRef50_A1DKB8 Cluster: Short-chain oxidoreductase, putative; n=2;
           Trichocomaceae|Rep: Short-chain oxidoreductase, putative
           - Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
           NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
           DSM 3700 / NRRL 181))
          Length = 324

 Score = 79.8 bits (188), Expect = 8e-14
 Identities = 62/211 (29%), Positives = 97/211 (45%), Gaps = 12/211 (5%)

Query: 26  RTIIITGAN--SGIGKAAAKDFAKRGAKVFMACRDVKKCE---EQRRDIVLETNNKYVYC 80
           +TI+ITGA+  S  G+ A +  A     + ++ R  ++     ++ + I    N +++  
Sbjct: 25  KTILITGASGDSIAGELAIQLSAADPHLLILSARAEERVTPIIQKIKSIAPNVNTRFL-- 82

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXX 140
              +L   + IR+ V     + P +  L   AGVM PP G TKDGFETQ GV        
Sbjct: 83  -KMNLGDMSCIRKAVDTLH-DIPKIDHLACVAGVMVPPYGTTKDGFETQFGVNYLANFLL 140

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQR-GRIHKQDLNMSE--NYDASAAYSQSKLANLLFA 197
                   +                R GR+H +D+  SE  +Y    AYSQS  A +LFA
Sbjct: 141 VKLLLPKVRAAGSGSSIIIVASSAARSGRVHFEDVGFSEGKSYIPLVAYSQSNAARVLFA 200

Query: 198 RELGRRLLGTGVATIAVDPGLVDTDITRHMS 228
           + L  +L   G+   ++DPG V + + RH +
Sbjct: 201 KALAEKLGDQGIRVFSIDPGAVRSGLQRHFT 231


>UniRef50_UPI000023EBC0 Cluster: hypothetical protein FG00213.1;
           n=1; Gibberella zeae PH-1|Rep: hypothetical protein
           FG00213.1 - Gibberella zeae PH-1
          Length = 308

 Score = 79.4 bits (187), Expect = 1e-13
 Identities = 83/298 (27%), Positives = 126/298 (42%), Gaps = 19/298 (6%)

Query: 12  YSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIV 70
           YS  P       D + I+ITGAN+G+GKA A + AK   A +++  R+  K      ++ 
Sbjct: 7   YSFNPAQDIPSLDGKVILITGANTGLGKATALELAKHNPAHIYITARNSTKGNTALEEVK 66

Query: 71  -LETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQ 129
            + +    V     DL+S  SI+     F   E  L VL+ NAGVM  P  +TKDG+E  
Sbjct: 67  GVASEGTQVSLLELDLSSFDSIKAAAKDFLDREVRLDVLLLNAGVMGAPPVLTKDGYEMH 126

Query: 130 LGVXXXXXXXXXXXXX-XXXKXXXXXXXXXXXXXXHQRG--RIHKQDLNMSEN-YDASAA 185
           +G                  K                 G   I    L  + +       
Sbjct: 127 IGTNHLGHALLLKLLTPVLDKTPNARVVHLFSAGFRHVGPNGIEFDTLKSATSPTPLPLR 186

Query: 186 YSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMS---MMKSVTRFFIYPLF 242
           Y+QSKLA LL+ARE  +R        IA++PG V T++    +   MMK +       + 
Sbjct: 187 YAQSKLACLLYAREAAKRY---NFTNIAINPGEVQTELFSRKAGDEMMKHLQENVAPKMA 243

Query: 243 WPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEA-QDFELAQWLWRVSE 299
            P  +    G +  + AA   ++K+  G++Y  + K    + A  D E+A  LW  +E
Sbjct: 244 GPISE----GVKNHLWAATSTEIKN--GEFYEPVGKTGGLEGAGLDEEMANKLWDWTE 295


>UniRef50_Q9KG00 Cluster: BH0316 protein; n=1; Bacillus
           halodurans|Rep: BH0316 protein - Bacillus halodurans
          Length = 312

 Score = 79.4 bits (187), Expect = 1e-13
 Identities = 42/106 (39%), Positives = 60/106 (56%), Gaps = 2/106 (1%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + R +IITGANSGIGK AA+ FA  G  V MACR++    + + DI+  + N +V     
Sbjct: 3   NRRIVIITGANSGIGKEAAQRFANEGDHVIMACRNIAFSRKVQHDIIAASGNDHVDLLEL 62

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVME--PPKGVTKDGFE 127
           D++S ASIR F   F  +   L +L++NA       P  ++ DG E
Sbjct: 63  DVSSFASIRTFCTTFNSQYKRLDILIHNAAYFNHGEPYRLSPDGIE 108


>UniRef50_A5CQ21 Cluster: Putative short chain alcohol
           dehydrogenase; n=1; Clavibacter michiganensis subsp.
           michiganensis NCPPB 382|Rep: Putative short chain
           alcohol dehydrogenase - Clavibacter michiganensis subsp.
           michiganensis (strain NCPPB 382)
          Length = 292

 Score = 79.4 bits (187), Expect = 1e-13
 Identities = 77/294 (26%), Positives = 117/294 (39%), Gaps = 22/294 (7%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           D RT++ITGA+SGIG+ AA++   RGA V +  RD     E+ R I  E   ++V     
Sbjct: 6   DGRTVVITGASSGIGRIAARELHDRGADVVVVGRD----PERTRGIAAELGARHVL---A 58

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFET--QLGVXXXXXXX-- 139
           D+     +R   A      P +HVL  NAG + P + +T DG ET  Q  V         
Sbjct: 59  DMDRLDEVRALGATLLETCPRIHVLALNAGSLVPRRAMTVDGHETTFQRNVLAPFLLTRL 118

Query: 140 ----XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN--YDASAAYSQSKLAN 193
                                       +  GR+   DL+  +        AY  SK   
Sbjct: 119 LLPRLEETQDALRADESPVRVIGTASRANLWGRVRLDDLDWRKRPWLGGWQAYGTSKAMM 178

Query: 194 LLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGG 253
           +L  R L  R+   G+   +  PGLV T      ++MK++    +      +    E G 
Sbjct: 179 ILMMRTLAERVGARGIEACSFHPGLVRTSFGSDSTVMKALLALSM----GAYGISAEAGA 234

Query: 254 QTVVHAALDPKLKDCAGDYYVDM-KKAEPSQEAQDFELAQWLWRVSEAWTKLDE 306
             +V  A  P L   +G Y+  +    + + +A D +L + LW   +     DE
Sbjct: 235 VPLVQLASVPDLGAPSGTYFDQLTPDGKTTAQAADRQLGRDLWAALDLAAGTDE 288


>UniRef50_A4RXP8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
           Predicted protein - Ostreococcus lucimarinus CCE9901
          Length = 324

 Score = 79.4 bits (187), Expect = 1e-13
 Identities = 69/256 (26%), Positives = 103/256 (40%), Gaps = 8/256 (3%)

Query: 23  ADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRP 82
           A    ++ITGA +GIG    K F   GA V +  RD  + +    +++ +T +  V    
Sbjct: 38  ASRNCVLITGATAGIGFETLKAFCSTGATVVVGARDEARAKALACELMSKTTS-IVRVLR 96

Query: 83  CDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKD---GFETQLGVXXXXXXX 139
            DL+ + S+  FV  F      L VLVNNAG+M  P          F  +  +       
Sbjct: 97  LDLSCSKSVHAFVDAFLALNLKLTVLVNNAGIMPCPFDADSHRDLAFHVKF-LNHFVLTQ 155

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                                   +  G I    ++    YD+  +Y+QSKLA LL+ R 
Sbjct: 156 LLLESFDPAGARVVNVTSEVYRFSYPEG-IRFGKIDDDRAYDSVKSYAQSKLALLLWTRY 214

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHA 259
            G  L   GV   AV PG V T  +             ++ +  PF+K  E G  T ++ 
Sbjct: 215 QGEALRERGVQFFAVHPGSVATQGSARARKSSGWRGALLHCVGAPFVKSVECGAATTIYC 274

Query: 260 ALDP--KLKDCAGDYY 273
           AL P   + +  G+YY
Sbjct: 275 ALHPGASMYNRFGEYY 290


>UniRef50_A0EEX1 Cluster: Chromosome undetermined scaffold_92, whole
           genome shotgun sequence; n=3; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_92,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 377

 Score = 79.4 bits (187), Expect = 1e-13
 Identities = 69/254 (27%), Positives = 120/254 (47%), Gaps = 17/254 (6%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           +++ ++ITGA+SGIG  AA++FAK  A V  ACRD    E   +++V ET N  ++    
Sbjct: 12  EDQIVVITGASSGIGMEAAREFAKLKATVIFACRDQDVTENIIQELVQETKNNKLHFIFL 71

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGV----MEPPKGVTKDGFETQLGVXXXXXXX 139
           DL  T S+  FV +FK +  +L++L+NN+G+     E   G+ K     Q+G        
Sbjct: 72  DLEQTDSVISFVEQFKQKFKYLNILINNSGIADFDQENVSGIEKIVKVNQIGWVLLTHQL 131

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                                       +  K DL+    Y  S  +   K+++ L+ ++
Sbjct: 132 IDYFNERGRIINIVSHMYTWIGEEIDILKAFKGDLDY--RYAISQYF---KVSSSLYLQQ 186

Query: 200 LGRRLLGTGVATIAVDPGLVDTDI----TRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQT 255
           L  +     +  + V PG V+T+I     ++  +++S+ R  +  +  PF+  P    QT
Sbjct: 187 L-LKDQNKDIKVLLVAPGAVNTEIFEKSLKNQVILRSLVR-VMKVIMDPFLLTPNEASQT 244

Query: 256 VVHAALDP--KLKD 267
            ++AAL P  ++KD
Sbjct: 245 YLYAALRPYDQIKD 258


>UniRef50_A2QR41 Cluster: Contig An08c0130, complete genome; n=1;
           Aspergillus niger|Rep: Contig An08c0130, complete genome
           - Aspergillus niger
          Length = 326

 Score = 79.4 bits (187), Expect = 1e-13
 Identities = 65/265 (24%), Positives = 107/265 (40%), Gaps = 23/265 (8%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCR---- 81
           +  I+TGA SG+G   A     + A V++A R   K      +I       +   R    
Sbjct: 26  KVTIVTGATSGVGFNTASILYSKNATVYIAARSADKARTAINEIQTSAEGAHSRGRLSFL 85

Query: 82  PCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKG-VTKDGFETQLGVXXXXXXXX 140
             DL++ ASI+E   +F   E  L +L++NAGVM PP G  T  G + ++G         
Sbjct: 86  QLDLSNLASIKESANKFLELEDRLDILIHNAGVMTPPAGSKTITGHDLEMGTNCLGPFLF 145

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAA-----------YSQS 189
                   +                   I     N    +D               Y +S
Sbjct: 146 NKFLLPLIQRTAAAAPASSVRVVWLSSMISSFTANGGIIFDEETGAPKVLSDPMQNYMES 205

Query: 190 KLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKP 249
           K+ N+  A+E+  R  G G+ +++V PGL+ T++ RH S +++    +I+       K P
Sbjct: 206 KVGNVFIAKEMANRDGGEGILSLSVHPGLMKTELQRHSSAIQATVMGWIF-------KGP 258

Query: 250 EIGGQTVVHAALDPKLKDCAGDYYV 274
             G  + + AAL P++       Y+
Sbjct: 259 RYGAYSELFAALSPEVTQEKNGAYI 283


>UniRef50_Q4PDD2 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 340

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 40/106 (37%), Positives = 58/106 (54%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           R  I+TG NSG+G+ +  + A+ GAKV+MA R   K +E  + I        ++    +L
Sbjct: 15  RVAIVTGGNSGLGEVSCLELARNGAKVYMASRTESKAQEAIQKIKQAIPKADIHFLQLNL 74

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLG 131
              A++R+    F   E  L +L+NNAGVM  P   TKDG E Q+G
Sbjct: 75  TELAAVRKAAEDFLSREQRLDILLNNAGVMATPYTFTKDGIELQVG 120



 Score = 38.7 bits (86), Expect = 0.19
 Identities = 34/124 (27%), Positives = 58/124 (46%), Gaps = 6/124 (4%)

Query: 186 YSQSKLANLLFARELGRRL-LGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWP 244
           Y +SKL N+L A EL + L     + ++++ PG+V T + R  +         +  L   
Sbjct: 194 YGKSKLGNILIANELSKLLPKDARITSLSIHPGVVRTGLLRGPNESYGKIIGSVNSLLSR 253

Query: 245 FMKKPEIGGQTVVHAALDPKLK--DCAGDYYVDMKK-AEPSQEAQDFE--LAQWLWRVSE 299
           F    E G  T ++A   P++   +  G Y V + K  + S+ AQD +  L Q L+    
Sbjct: 254 FFTAAEDGALTQLYACTSPEVDRLNLNGAYLVPVAKLGQKSKLAQDTDGRLGQELFSFCN 313

Query: 300 AWTK 303
           ++ K
Sbjct: 314 SFIK 317


>UniRef50_A2R0W5 Cluster: Remark: also show homology to different
           oxidoreductases; n=2; Pezizomycotina|Rep: Remark: also
           show homology to different oxidoreductases - Aspergillus
           niger
          Length = 320

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 75/288 (26%), Positives = 113/288 (39%), Gaps = 14/288 (4%)

Query: 26  RTIIITGANS-GIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           +T +ITGA    IG   A   AK G + + +A R + K      +I    +         
Sbjct: 24  KTFVITGAGKPSIGSQMATSLAKAGPSHILIASRTLSKVHPVLDEIHTIDSTIKTTAVEV 83

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPK-GVTKDGFETQLGVXXXXXXXXXX 142
           DL    S+R          P + VL+N+AGVM   +  + K G E QL            
Sbjct: 84  DLTDHESVRRAAGEILAAAPKIDVLINSAGVMAIKEYTLDKQGIELQLSANHVGHFLLTN 143

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS--ENYDASAAYSQSKLANLLFAREL 200
                                +       +D N S  + YD    Y Q+K AN+LF    
Sbjct: 144 MLIPALISAGSARVVNLTSAGYLVSPFRFEDWNYSNGKEYDPWTGYGQAKTANILFTYGF 203

Query: 201 GRRLLGTGVATIAVDPGL-VDTDITRHMSMMKSVTRFFI--------YPLFWPFMKKPEI 251
            +RL   G+A +AV PG   DT +  H++ +     + +        +    P  K    
Sbjct: 204 SQRLKHKGIAAVAVHPGYNGDTKLGSHLTWVDYAKIYAVAIRNTGKEFVFEEPRFKTYTQ 263

Query: 252 GGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
              T + AALDP+L+  A  Y  +   +E ++ A+D   A  LWR+SE
Sbjct: 264 IAATPLIAALDPELQALAPVYMQNSVVSEAAEHARDPASADALWRLSE 311


>UniRef50_Q4JMZ6 Cluster: Putative uncharacterized protein; n=1;
           uncultured bacterium BAC13K9BAC|Rep: Putative
           uncharacterized protein - uncultured bacterium
           BAC13K9BAC
          Length = 274

 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 67/276 (24%), Positives = 116/276 (42%), Gaps = 14/276 (5%)

Query: 27  TIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETN---NKYVYCRPC 83
           T IITGA SGIG   AK  AK   K+ +  R++ K E  +R +  + N   + Y Y    
Sbjct: 3   TTIITGATSGIGLETAKGLAKEKHKLILVSRNLSKLESTKRLLDSDYNIDCDIYKY---- 58

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DL+       F  +       +  L+NN G +   +  T +G E   G+           
Sbjct: 59  DLSLIKENVNFYEQILKRYGDIDFLINNVGAIFMKREETIEGLEKTFGLNHMSYFVLSKL 118

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRR 203
                +              H+   +   DL   +NY+   +Y +SKLAN+    EL +R
Sbjct: 119 FS---QQGNPLRIINVSSEAHRNITLGFDDLQNKKNYNGWYSYKKSKLANIYLTYELHKR 175

Query: 204 LLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDP 263
           LL +      + PG+V+T+     ++   +    +  L   F   P+ G QT+++   + 
Sbjct: 176 LLKSKSTVNCLHPGVVNTNFANDNALPFKI----MASLIKYFGVSPKEGSQTILYLVNNN 231

Query: 264 KLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
            +++ +G Y+      E S  + + + ++ LW  SE
Sbjct: 232 DIRNASGLYFKKCMPVESSLVSHNQKSSEKLWDYSE 267


>UniRef50_A7QG31 Cluster: Chromosome undetermined scaffold_91, whole
           genome shotgun sequence; n=1; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_91, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 159

 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 47/133 (35%), Positives = 73/133 (54%), Gaps = 9/133 (6%)

Query: 168 RIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLLGTGVATIA--VDPGLVDTDITR 225
           RI  +++N    Y +  AY QSKL+N+L A EL RR    GV   A  + PG++ T++ R
Sbjct: 28  RIRFENINDKSGYSSLYAYGQSKLSNILHANELARRFKEDGVNMTANSLYPGMIVTNLFR 87

Query: 226 HMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEA 285
           H +++     +F + L    M     G  T  + AL P++K  +G Y+ D   A+P+ +A
Sbjct: 88  HSNIVTG--NYFTFLLLISLM-----GAATTCYVALHPQVKGVSGQYFSDCNIAKPTAQA 140

Query: 286 QDFELAQWLWRVS 298
           +D ELA+ LW  S
Sbjct: 141 KDPELAKKLWEFS 153


>UniRef50_Q4PD53 Cluster: Putative uncharacterized protein; n=1;
           Ustilago maydis|Rep: Putative uncharacterized protein -
           Ustilago maydis (Smut fungus)
          Length = 771

 Score = 78.6 bits (185), Expect = 2e-13
 Identities = 69/255 (27%), Positives = 111/255 (43%), Gaps = 15/255 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACR----DVKKCEEQRRDIVLE--TNNKYVY 79
           +T++I+G+NSGIGK AA  FA+ GA V MACR      +  EE R++IV     ++  V 
Sbjct: 436 KTVLISGSNSGIGKQAALYFARAGATVVMACRFTATHEQNPEEARKEIVATAGVDDSKVE 495

Query: 80  CRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXX 139
               D +S A+I +F  +++     L +LVNNAG+    + +T +GFE    +       
Sbjct: 496 LWEIDCSSLANIEKFGIKWRESGRTLDILVNNAGLSAGKRRITDEGFELTHVINLLSHCL 555

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLN----MSENYDASAAYSQSKLANLL 195
                                   H  G++   +++     S   D   AY  +KL  L+
Sbjct: 556 LTFYLLPSLNKSAAPRIINTCSCFHAGGKLDFANMDNEKLTSLGPDCVQAYCDTKLWFLM 615

Query: 196 FARELGRRLLGTG----VATIAVDPGLVDTDITRHM-SMMKSVTRFFIYPLFWPFMKKPE 250
           ++ EL  RL  +     V    + PG V ++I  +  + +    R              E
Sbjct: 616 WSVELQDRLSRSDDYRHVIVHGIHPGFVGSNIWHNPDTRIPYPLRIIFQSAISKLSINSE 675

Query: 251 IGGQTVVHAALDPKL 265
            G   ++HAAL+P L
Sbjct: 676 QGSYAIIHAALEPSL 690


>UniRef50_Q61C15 Cluster: Putative uncharacterized protein CBG13117;
           n=1; Caenorhabditis briggsae|Rep: Putative
           uncharacterized protein CBG13117 - Caenorhabditis
           briggsae
          Length = 350

 Score = 78.2 bits (184), Expect = 3e-13
 Identities = 75/290 (25%), Positives = 119/290 (41%), Gaps = 18/290 (6%)

Query: 24  DNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + +T  ITG  SGIG   A+  A +GA V M  R++ + E+ ++ I  E ++  +    C
Sbjct: 35  NGKTYAITGTTSGIGIETARALALKGAHVVMFNRNIVESEKLKKRIEDEQSDVKIDFISC 94

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DL S  S +     F  +   LH L+ NAGV  P   +T D FE+  GV           
Sbjct: 95  DLNSLQSAKAAADVFLSKHWPLHGLILNAGVFAPNTKMTFDNFESHCGVNHLAQFLLVKE 154

Query: 144 XXXXXKXXX-------XXXXXXXXXXXHQRGRIHKQDLNMSENYDA--SAAYSQSKLANL 194
                +                      +  R  K      EN +      Y+ SK+  +
Sbjct: 155 LLPALRQSSPSRIVFVSSVSSSHTGLKAEMTRNEKVKKLCPENANEFYYKLYAYSKMCQV 214

Query: 195 LFARELGR-RLLGTGVATIAVDPG-LVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIG 252
           L A ++ R   +  G++T A+ PG ++ TDI+R           F   +  PF K    G
Sbjct: 215 LTAFKIHRDEYVSNGISTYAIHPGTMIGTDISRGFGFFGK----FWNVISKPFTKTLAQG 270

Query: 253 GQTVVHAALDPKLKDCAGDYYV---DMKKAEPSQEAQDFELAQWLWRVSE 299
             T V+    P + + +G ++    D +K+  +  A+D  L   LW  SE
Sbjct: 271 AATSVYCVAHPDVAELSGKFWESCWDDEKSLDADIARDISLQDELWEHSE 320


>UniRef50_Q4W9Y6 Cluster: Oxidoreductase, short-chain
           dehydrogenase/reductase family; n=1; Aspergillus
           fumigatus|Rep: Oxidoreductase, short-chain
           dehydrogenase/reductase family - Aspergillus fumigatus
           (Sartorya fumigata)
          Length = 345

 Score = 78.2 bits (184), Expect = 3e-13
 Identities = 77/297 (25%), Positives = 121/297 (40%), Gaps = 23/297 (7%)

Query: 26  RTIIITGANSG-IGKAAAKDFAKRGAKVF-MACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + I+ITG + G +G++  K  A     +F +A R + K +    ++     +  V     
Sbjct: 40  KIILITGVSPGSLGESFVKQVAVAQPAMFILASRSISKVQNLIDELATAYPSVKVKPLYL 99

Query: 84  DLASTASIREFVARFKG--EEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX 141
           +L S   +RE         + PH+ +LVNNAG+M  P  +T+DG+E+Q            
Sbjct: 100 NLLSFDDVREAAETVNSWTDVPHIDILVNNAGIMAVPYKLTEDGYESQFQTNHLSHFLLT 159

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS--ENYDASAAYSQSKLANLLFARE 199
                                 H+ G IH  D N +  ++Y     YSQSK AN L    
Sbjct: 160 NLLMGKILASKTPRIVVVSSNVHRIGHIHWSDPNFNGGKHYQRWLGYSQSKTANALMGVS 219

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRH-----MSMMKSVTRF-FIYPLFWPF------MK 247
           L  +L   G+    + PG+  T++  H      +    +T    IY   W +      +K
Sbjct: 220 LAEKLGHRGLLAFPICPGVSLTNLAAHGREDLAAFSADLTDMDNIYGNKWLWGMAEMKIK 279

Query: 248 KPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQE-----AQDFELAQWLWRVSE 299
             + G  T V AA D  + +  G +  D   A+P  E     A     A+ LWR+SE
Sbjct: 280 DLDQGAATHVFAAFDTSIANQNGAFLSDCHAADPDMEEVHSWATSKVDAERLWRMSE 336


>UniRef50_A0AC89 Cluster: Putative oxidoreductase; n=1; Streptomyces
           ambofaciens ATCC 23877|Rep: Putative oxidoreductase -
           Streptomyces ambofaciens ATCC 23877
          Length = 334

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 71/254 (27%), Positives = 99/254 (38%), Gaps = 13/254 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           RT +ITG++ GIG AAA+  A+ GA V +AC   ++       +  +  +       CDL
Sbjct: 30  RTAVITGSSRGIGAAAAQHLARCGAHVIIACPSAEEGRSAADAVRRQVASARAESVVCDL 89

Query: 86  ASTASIREFVARFKG-EEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXX 144
              A + E   R        LH+L+NNAGV   P   + DGFE    V            
Sbjct: 90  GDLAQVHEAAERITALAGRRLHLLINNAGVAALPPTRSADGFEMHFAVNHIGHFALTGRL 149

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAREL--GR 202
                              H  GR   +  +  + Y    AY  SKLA LLF   L    
Sbjct: 150 LPALLNTPRPRVVNVSSVLHWLGRNGARP-HEPQRYHRWQAYFDSKLAALLFTHGLVTWA 208

Query: 203 RLLGTGVATIAVDPGLVDTDITRHM---SMMKSVTRFFI-YPLFWPFMKKPEIGGQTVVH 258
           R     +  +   PGLVDT +  H+   +  K+  R        W     P     T+V 
Sbjct: 209 RAHRLPLGAVTAHPGLVDTTLASHVLHTTGRKAEARLLRGLQTRW---ASPAAAAWTLVR 265

Query: 259 AALDPKLKDCAGDY 272
           AA DP +   AG++
Sbjct: 266 AATDPHIS--AGEF 277


>UniRef50_Q4QHL1 Cluster: Dehydrogenase-like protein; n=3;
           Leishmania|Rep: Dehydrogenase-like protein - Leishmania
           major
          Length = 412

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 66/258 (25%), Positives = 102/258 (39%), Gaps = 19/258 (7%)

Query: 28  IIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAS 87
           ++ITG   GIGK       + G  V + C    +       +    +N  V+    DL  
Sbjct: 115 VVITGGERGIGKEVVHQLLREGVDVILCCPFEAEALRTIARLKARVSNSRVHFVKLDLND 174

Query: 88  TASIREFVARFKGEEPHLHVLVNNAGVMEP-PKGVTKDGFETQLGVXXXXXXXXXXXXXX 146
             S+RE  A   G  P + VL+NN+G++ P    + K G+E  L +              
Sbjct: 175 EESVRECAAEVLGMTPRIDVLINNSGLVSPLSHKLNKRGYEVVLSINFLGHVLFTELLLE 234

Query: 147 XXKXXXXXXXXXXXXXXHQRGRIH---KQDLN-MSENYDASAA-----YSQSKLANLLFA 197
             K              H    +    K  L+ M+ N D ++      YS SKL  + + 
Sbjct: 235 RVKASGPSRIVNVASLMHLDACVEGPCKTALDVMAANCDPTSPHHTRNYSLSKLLLVCYT 294

Query: 198 RELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVV 257
           R+L R L GT  A   + PG+V TDI        +    F+   F    K P  G + V+
Sbjct: 295 RDLARHLRGTDTAVATLHPGVVITDI-------YAFAVIFMRVFFRTVFKFPGEGAEVVL 347

Query: 258 HAALDPKLKDCAGDYYVD 275
           + AL   ++  +G +Y D
Sbjct: 348 YCALADNIR--SGSFYAD 363


>UniRef50_A0D7N4 Cluster: Chromosome undetermined scaffold_40, whole
           genome shotgun sequence; n=1; Paramecium
           tetraurelia|Rep: Chromosome undetermined scaffold_40,
           whole genome shotgun sequence - Paramecium tetraurelia
          Length = 321

 Score = 77.8 bits (183), Expect = 3e-13
 Identities = 68/292 (23%), Positives = 119/292 (40%), Gaps = 7/292 (2%)

Query: 13  SGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLE 72
           +GP    +V    +  I+TG+++G+GK  AK  A+RGA V  ACR  +K +    +I   
Sbjct: 25  AGPKRTYNVDLTGKIAIVTGSSAGVGKETAKKLAQRGATVIFACRSKEKTQIIIDEISKI 84

Query: 73  TNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGV 132
           + NK ++    DL +  S+R+FV  FK        L+NNAG+    +       E     
Sbjct: 85  SKNKNLHYINLDLPNYDSVRQFVKEFKQRFNQCDYLINNAGIFIINEQKNNLNHELTFAT 144

Query: 133 XXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLA 192
                                            R     Q     E     + Y+ +K A
Sbjct: 145 NHLGHFLLTNLLLDVMSDKSRIINVASGAHEFVRSAPDFQKAIKGEIGMGMSTYATTKFA 204

Query: 193 NLLFARELGRRL--LGTGVATIAVDPGLVDTDI--TRHMS--MMKSVTRFFIYPLFWPFM 246
           N+LF + L ++       +  +++ PG V T+I  +++ S  ++ ++    IY L   F 
Sbjct: 205 NILFTQALQQKFDKENRRIKAVSLHPGFVRTEIFGSKNGSNRILSAIATVVIY-LMSQFS 263

Query: 247 KKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
              E G +T  +  L P  +     YY   + ++ ++  ++  L   LW +S
Sbjct: 264 LNEEQGSRTTEYTMLQPYEELVPQGYYQKNQLSKSTKLVRECGLETQLWDLS 315


>UniRef50_Q0C051 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Hyphomonas
           neptunium ATCC 15444|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 364

 Score = 77.4 bits (182), Expect = 5e-13
 Identities = 62/210 (29%), Positives = 90/210 (42%), Gaps = 10/210 (4%)

Query: 24  DNRTIIITGAN-------SGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNK 76
           + R +++TGAN       SG+G   A   A+ GA V +A R+  + EE  R I  E+   
Sbjct: 65  NGRRVLVTGANGYPEEDRSGLGYHIALGLARAGADVIIASRNQTRGEEAIRRIGAESPAG 124

Query: 77  YVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEP-PKGVTKDGFETQLGVXXX 135
            V     DLA   S+++F AR +     L +LVNNAG M    +  + DGFE        
Sbjct: 125 RVRFETLDLADLKSVKDFTARMQASGNGLDLLVNNAGTMGTLERQESIDGFERVFATNAI 184

Query: 136 XXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLL 195
                        +                 G +   DL     Y+ ++AY+ SK A+L+
Sbjct: 185 GPFALTAGLLPLLRNGNAPRIVWMCSGRSAFGALDLDDLQQENAYEYASAYNDSKQAHLI 244

Query: 196 FARELGR--RLLGTGVATIAVDPGLVDTDI 223
            A E  R  R  G GV +IA  PG+  T +
Sbjct: 245 AALECERRSRAHGWGVVSIAAHPGVARTSL 274


>UniRef50_Q0UF48 Cluster: Putative uncharacterized protein; n=1;
           Phaeosphaeria nodorum|Rep: Putative uncharacterized
           protein - Phaeosphaeria nodorum (Septoria nodorum)
          Length = 309

 Score = 77.4 bits (182), Expect = 5e-13
 Identities = 71/292 (24%), Positives = 121/292 (41%), Gaps = 23/292 (7%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           + I ITG N+G+GK AA   A+    ++ +  R  +       +IV       +     D
Sbjct: 15  KVIFITGGNAGLGKEAALILAEHNPGRILIGSRSEENARAAIAEIVKSVPGAQLTPIQMD 74

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX--- 141
           LAS +S++E  ++       L VL+NNAG+M  P   T DG+E Q G             
Sbjct: 75  LASLSSVKEAASKVLATTSRLDVLMNNAGIMAVPPATTVDGYEIQFGTNHMGHALLTKLL 134

Query: 142 --XXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSE------NYDASAAYSQSKLAN 193
                    +              H   R  +  ++ S        +     Y  SKLAN
Sbjct: 135 LPLLLKTAEQQQPGSDVRIVALTSHSHTRAPEGGIDFSRLRSADPEFSILTKYGVSKLAN 194

Query: 194 LLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGG 253
           +L  ++L +R     + ++A+ PG+V+T+++  M    S+  + + P+   +    +I  
Sbjct: 195 ILHVKQLAKRY--PTIKSVAIHPGMVNTNLSTTM-RQGSMLAWILMPVV-SYFSAVDI-K 249

Query: 254 QTVVHAALDPKLKDC-AGDYYVDM-KKAEPSQEAQDFELAQWLWRVSEAWTK 303
           Q V++        D  +G YY  +      S   +D +LA+ LW    AWT+
Sbjct: 250 QGVLNQLWGATSADAESGQYYEPVGVGGNGSPPTEDLKLAEKLW----AWTE 297


>UniRef50_Q3WBA5 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=1; Frankia sp. EAN1pec|Rep: Short-chain
           dehydrogenase/reductase SDR - Frankia sp. EAN1pec
          Length = 336

 Score = 77.0 bits (181), Expect = 6e-13
 Identities = 72/266 (27%), Positives = 105/266 (39%), Gaps = 8/266 (3%)

Query: 19  RSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYV 78
           RS     R  ++TGA+SGIG   A+  A  GA V +  RDV   EE  R++        +
Sbjct: 34  RSADLRGRVAVLTGASSGIGVETARALAATGADVVLGVRDVAAGEELVREVRAGATGD-I 92

Query: 79  YCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXX 138
                DL+   S+  F A+  G    + +L+ NAGV   P+    +G + +         
Sbjct: 93  RAERLDLSDLGSVVAFAAQVTGP---VDLLIANAGVSRTPESHLPNGLDVRFATNHLGHF 149

Query: 139 XXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLN-MSENYDASAAYSQSKLANLLFA 197
                                    H+   +   DL   +  ++   AY++SK AN+LFA
Sbjct: 150 LLALRLSEQL-AERGARIVVVSSGAHRSIPVRLDDLQWTARRHNPGMAYAESKTANILFA 208

Query: 198 RELGRRLLGTGVATIAVDPGLVDTDITR-HMSMMKSVTRFFIYP-LFWPFMKKPEIGGQT 255
           +E  RR    G+   AV PG   T + R H   MK    F        P +K P     T
Sbjct: 209 QEATRRWGPDGIFANAVLPGSALTGLQRFHGDEMKRRIGFLNEDGSPNPVLKSPAQAAAT 268

Query: 256 VVHAALDPKLKDCAGDYYVDMKKAEP 281
            + AA  P+L    G    D  +A P
Sbjct: 269 TLWAATAPELAGRGGLVLEDCAEALP 294


>UniRef50_A4T8M7 Cluster: Short-chain dehydrogenase/reductase SDR;
           n=5; Mycobacterium|Rep: Short-chain
           dehydrogenase/reductase SDR - Mycobacterium gilvum
           PYR-GCK
          Length = 301

 Score = 77.0 bits (181), Expect = 6e-13
 Identities = 61/211 (28%), Positives = 104/211 (49%), Gaps = 16/211 (7%)

Query: 28  IIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAS 87
           II+TGA +G+G A A   A+ GA+V +A R+++   ++  ++  +T+         DLA 
Sbjct: 23  IIVTGATNGVGLATATALARAGAQVILAVRNLELGAQRAAEMGGDTS-----VVELDLAD 77

Query: 88  TASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXXX 147
            +S+R F + F G+   + VL+NNAG +   +  T DGFE  LG                
Sbjct: 78  QSSVRAFPSLFDGD---VDVLINNAGAVAQHRTDTVDGFENTLGTNFLGPFALTNLLYGR 134

Query: 148 XKXXXXXXXXXXXXXXHQRGRIHKQDLNM-SENYDASAAYSQSKLANLLFARELGRRL-- 204
            +              H+   I+  D ++ ++ +    AY++SKLA +L+  EL RRL  
Sbjct: 135 VR----SKIVNVGSDAHKTASINFDDPHLRTDKWSPFPAYARSKLAVMLWGLELDRRLRA 190

Query: 205 LGTGVATIAVDPGLVDTDITRHMSMMKSVTR 235
            G+ V T    PG V +++ + +S  + +TR
Sbjct: 191 AGSPVTTYLTHPGWVSSNLAK-VSDTRLMTR 220


>UniRef50_Q7QES1 Cluster: ENSANGP00000019888; n=1; Anopheles gambiae
           str. PEST|Rep: ENSANGP00000019888 - Anopheles gambiae
           str. PEST
          Length = 201

 Score = 77.0 bits (181), Expect = 6e-13
 Identities = 47/126 (37%), Positives = 67/126 (53%), Gaps = 4/126 (3%)

Query: 185 AYSQSKLANLLFARELGRRLLGTGVATIA--VDPGLV-DTDITRHMSMMKSV-TRFFIYP 240
           A++ SKLA +L +R L  +L   G +T      PGLV  T   RH  +MK++  +   +P
Sbjct: 64  AFAHSKLAIVLGSRALAGKLTAEGCSTTVNCCSPGLVRGTGHLRHSPIMKALFAKVLTFP 123

Query: 241 LFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEA 300
             W FMK P  G  T+V    DP L  C G ++ D ++ E S+ A+D ELA  L+R S +
Sbjct: 124 WMWLFMKSPAQGAHTIVRLVTDPALAGCTGVFFNDCERVEVSELARDDELADRLYRASLS 183

Query: 301 WTKLDE 306
              L E
Sbjct: 184 AVGLTE 189


>UniRef50_UPI0000D57166 Cluster: PREDICTED: similar to CG2065-PA;
           n=1; Tribolium castaneum|Rep: PREDICTED: similar to
           CG2065-PA - Tribolium castaneum
          Length = 249

 Score = 76.6 bits (180), Expect = 8e-13
 Identities = 50/176 (28%), Positives = 76/176 (43%), Gaps = 6/176 (3%)

Query: 50  AKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLV 109
           A++ +ACRD  + E+ R  I+ ET N+ ++ +  DL S  S++ F  +    E  L +LV
Sbjct: 11  ARIILACRDKNRAEKARLRIINETGNENIHVKIIDLGSFESVKNFAKKISESENRLDILV 70

Query: 110 NNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRI 169
           NNAGV+      T +G    + V                K                    
Sbjct: 71  NNAGVLAQGHKTTPNGHPLIMQVNYYSAFLLTKLLLDLLKKTKSRVVNVSSNGAGMALLF 130

Query: 170 HKQDLN--MSENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDI 223
           +   LN  M++  D    Y  SKL N+LF +EL ++L GT V   +  PG+  T I
Sbjct: 131 NLSKLNRHMTDGVD----YFNSKLCNVLFTQELAKKLDGTQVTAYSDHPGITKTQI 182


>UniRef50_Q7XCH4 Cluster: NAD dependent epimerase/dehydratase family
           protein, expressed; n=3; Magnoliophyta|Rep: NAD
           dependent epimerase/dehydratase family protein,
           expressed - Oryza sativa subsp. japonica (Rice)
          Length = 330

 Score = 76.6 bits (180), Expect = 8e-13
 Identities = 70/241 (29%), Positives = 101/241 (41%), Gaps = 26/241 (10%)

Query: 21  VRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYC 80
           V A     +ITGA+SGIG   A+  A RG +V MA R+V         I  E     ++ 
Sbjct: 25  VDARGLVAVITGASSGIGLETARVMALRGVRVVMAVRNVAAGHRASEAIRAEIPGAGIHV 84

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQ-----LGVXXX 135
              DL+S  S+R F   F+     L++L+NNAG+M      + DG E Q     +G    
Sbjct: 85  LEMDLSSMDSVRRFATEFEALNLPLNILINNAGIMTRNCTRSIDGLELQFATNHIGHFLL 144

Query: 136 XXXXXXXXXXXXXKXXXXXXXXXXXXXXH----QRGRIHKQDLNMSENYDASAAYSQSKL 191
                        K              H     +G I    +     + +  AY QSKL
Sbjct: 145 TNLLLENMKRTSSKTGVEGRIVNVSSSAHFVTYPKG-ICFDKVKEPSRFISLIAYGQSKL 203

Query: 192 ANLLFARELGRRLL------------GTGVATIAVDPGLVDTDITRHM----SMMKSVTR 235
           AN+L + EL R L             G  ++  AV PG+V T++ RH     +++KS+ R
Sbjct: 204 ANILHSTELSRVLKNNRETVEYEQEDGVNISANAVHPGVVTTNLFRHRTIINALVKSIGR 263

Query: 236 F 236
           F
Sbjct: 264 F 264


>UniRef50_A1C4C7 Cluster: Short-chain dehydrogenase; n=7;
           Pezizomycotina|Rep: Short-chain dehydrogenase -
           Aspergillus clavatus
          Length = 341

 Score = 76.6 bits (180), Expect = 8e-13
 Identities = 69/263 (26%), Positives = 109/263 (41%), Gaps = 12/263 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + I+ITGA SGIG   A+     GA +F+  R++ K  +    I LE     V     DL
Sbjct: 40  KVIVITGATSGIGVETARALKATGATLFLTARNLAKAHKNLAGI-LEPG--IVSLVGMDL 96

Query: 86  ASTASIREFVARF-KGEEPHLHVLVNNAGVM-EPPKGVTKDGFETQLGVXXXXXXXXXXX 143
            S  SI     +     +  +++L+NNAGVM +    +T+DG E                
Sbjct: 97  HSFKSICAGAEQILSATQGQVNILINNAGVMGQQTYTLTEDGIEAHFSGNYMGFFLLFQL 156

Query: 144 XXXXXKXXXX----XXXXXXXXXXHQRGRIHKQD-LNMSEN-YDASAAYSQSKLANLLFA 197
                                   H+   +   D  N  +  Y    AYS SKLA +  A
Sbjct: 157 LKQALLASVTPDFHSRVVVVASSAHRAATLPASDNYNFEKGGYSHEIAYSNSKLAAVYLA 216

Query: 198 RELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVV 257
            ++ R     G+   ++ PG ++TDI+R+M   + +      P     +K  E G  T V
Sbjct: 217 NKIERDYSAQGLHATSLHPGAINTDISRNMP-PEFLEGLMTNPYILKILKSAEQGAATTV 275

Query: 258 HAALDPKLKDCAGDYYVDMKKAE 280
            AA+  + ++  G Y  D+++AE
Sbjct: 276 WAAVSKEWENNGGKYLEDVREAE 298


>UniRef50_Q9CDH0 Cluster: Oxidoreductase; n=3; Lactococcus
           lactis|Rep: Oxidoreductase - Lactococcus lactis subsp.
           lactis (Streptococcus lactis)
          Length = 339

 Score = 76.2 bits (179), Expect = 1e-12
 Identities = 59/221 (26%), Positives = 91/221 (41%), Gaps = 10/221 (4%)

Query: 19  RSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYV 78
           +++    +TIIITG  SGIG    K  ++ GAK+ +  R ++  ++    I      K +
Sbjct: 23  KNINLSGKTIIITGGYSGIGLEMTKQLSRAGAKIIIPARRMEVAKKNLSKI------KNI 76

Query: 79  YCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXX 138
              P DL +  SI +F   F      L +L+N+AG+M  P      G E           
Sbjct: 77  DILPLDLTNPESIHQFAESFLQNNSKLDILINSAGLMYLPLKRDSRGIEYHFATNHLGHY 136

Query: 139 XXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS--ENYDASAAYSQSKLANLLF 196
                     K               Q   +  +D N    ENY+    Y QSK AN+LF
Sbjct: 137 QLTLELLPALKNAKISRVINLSSRAQQMTPL-LEDWNFEKIENYNPQIGYQQSKTANVLF 195

Query: 197 ARELGRRLLGTGVATIAVDPGLVD-TDITRHMSMMKSVTRF 236
           + +L       G+ + AV PG++  T+I R  S +    R+
Sbjct: 196 SIKLDELGKKYGIRSFAVHPGMIPMTNIGRQNSPITPWLRY 236


>UniRef50_Q6NLR7 Cluster: At5g04070; n=4; Magnoliophyta|Rep:
           At5g04070 - Arabidopsis thaliana (Mouse-ear cress)
          Length = 359

 Score = 76.2 bits (179), Expect = 1e-12
 Identities = 73/289 (25%), Positives = 120/289 (41%), Gaps = 22/289 (7%)

Query: 29  IITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDLAST 88
           +ITGA SG+GKA A   +++G  V +  R      +   DI  +  +  +     D++S 
Sbjct: 62  VITGATSGLGKATAFALSRKGFYVVLVGRSSHLLSKTLSDIKRQNEDAKLKAFEVDMSSF 121

Query: 89  ASIREFVARFKGE--EPHLH----VLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX 142
             + +F +  +    E  LH    +LVNNAG++      T +GF+  +            
Sbjct: 122 QLVLKFRSSLEQWLFESDLHSSVQLLVNNAGILATSSRPTVEGFDRMIATNYVGAFSLTK 181

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQR----GRIHKQDL-----NMSENYDASAAYSQSKLAN 193
                 +                R    GR     +     + S+ Y  +  Y  SKL  
Sbjct: 182 LLLPLLRNSPVPSRVVNVTSFTHRSAFTGRFDMDSVTGVNFSRSKQYPCARIYEYSKLCL 241

Query: 194 LLFARELGRRLL----GTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKP 249
           LLF+ EL R+L        ++ +AVDPG V T+I   +     V  F    +    M+ P
Sbjct: 242 LLFSYELHRQLHLMDDSHHISVVAVDPGAVKTNIMHELPSYIQVIAFCGLKIL-GLMQSP 300

Query: 250 EIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           E   ++V+ AAL P   + +G Y+   +  E S  + D ++A+ LW  S
Sbjct: 301 EDAAESVIDAALAP--PEISGKYFFGGRTIESSTLSSDPKMAKELWDTS 347


>UniRef50_A4R4N5 Cluster: Putative uncharacterized protein; n=1;
           Magnaporthe grisea|Rep: Putative uncharacterized protein
           - Magnaporthe grisea (Rice blast fungus) (Pyricularia
           grisea)
          Length = 376

 Score = 76.2 bits (179), Expect = 1e-12
 Identities = 74/260 (28%), Positives = 119/260 (45%), Gaps = 29/260 (11%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLETNNK-------- 76
           +T+I+TG NSG+G+ AA+ FA+ G AKV +ACRD  K E  R DI + T +         
Sbjct: 47  KTVIVTGGNSGLGREAARYFARLGAAKVILACRDTAKGEVARADIEVSTRSSRPPSAAGV 106

Query: 77  --YVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQ----- 129
              V     D++S +S+ +F AR + E P L  LV NAGV        + G+E+      
Sbjct: 107 RLAVEVWQVDMSSGSSVHDFCARVERELPRLDSLVLNAGVAIGAFVECEGGWESSVAINV 166

Query: 130 LGVXXXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRI--HKQDLNMSENYDASA--- 184
           +G                 +              H        K+   + + + ++A   
Sbjct: 167 IGTFLMAVLCLPIMRRTAAQHNVAPTIAVVASEAHVFASFAERKRQGLIFDAFKSAADMN 226

Query: 185 --AYSQSKLANLLFARELGRRL-LGTGVATIAVDPGLVDTDITRHMSM-MKSVTRFFIYP 240
              Y+ +KL ++L AREL  RL   + V   A++PGL  +++ RH    + ++ R  +  
Sbjct: 227 EDRYNVTKLLDVLLARELAARLGPDSPVVVNALNPGLCQSELFRHCPFPLSALLRLGLMI 286

Query: 241 LFWPFMKKPEIGGQTVVHAA 260
           L     +K E+G +T+V AA
Sbjct: 287 L----GRKTEVGSRTLVAAA 302


>UniRef50_Q2UB72 Cluster: Predicted protein; n=1; Aspergillus
           oryzae|Rep: Predicted protein - Aspergillus oryzae
          Length = 141

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 44/130 (33%), Positives = 68/130 (52%), Gaps = 1/130 (0%)

Query: 3   VSFLFNRDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKC 62
           ++FLF + +Y+ P     V    +++++TGANSG+G   A + A  GAKV  A R V K 
Sbjct: 9   LAFLFRQLFYTIPEVP-PVELHGKSVLVTGANSGVGFCLALELASHGAKVLAAVRSVPKG 67

Query: 63  EEQRRDIVLETNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVT 122
           E  ++ I+       V  + CDLAS  S++ F  + K E     +++ NAGV       +
Sbjct: 68  EAAKQRILERVPTAQVDVQECDLASFDSVKAFANQMKQESKTFDLVILNAGVWCSQWMAS 127

Query: 123 KDGFETQLGV 132
            DGF+  L V
Sbjct: 128 TDGFDISLQV 137


>UniRef50_Q5DEA2 Cluster: SJCHGC03296 protein; n=1; Schistosoma
           japonicum|Rep: SJCHGC03296 protein - Schistosoma
           japonicum (Blood fluke)
          Length = 180

 Score = 75.4 bits (177), Expect = 2e-12
 Identities = 46/126 (36%), Positives = 56/126 (44%), Gaps = 1/126 (0%)

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXX 143
           DLAS  SIREF  R       L  L+NNAG++      T DGFE  +GV           
Sbjct: 55  DLASQQSIREFARRILATYTKLDFLINNAGLIVNKYEKTSDGFEMTMGVNHFGTFLLTQL 114

Query: 144 XXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSEN-YDASAAYSQSKLANLLFARELGR 202
                K              H RG + K DL + +N Y+   AY  SKLAN ++A ELG 
Sbjct: 115 LLPLLKRSTPCRIIILSSLAHYRGHLMKPDLQLQQNEYNQVKAYCDSKLANAMYAAELGE 174

Query: 203 RLLGTG 208
           RL   G
Sbjct: 175 RLKTAG 180


>UniRef50_UPI0000498BBC Cluster: conserved hypothetical protein;
           n=1; Entamoeba histolytica HM-1:IMSS|Rep: conserved
           hypothetical protein - Entamoeba histolytica HM-1:IMSS
          Length = 298

 Score = 74.5 bits (175), Expect = 3e-12
 Identities = 68/272 (25%), Positives = 108/272 (39%), Gaps = 22/272 (8%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + + ITG +SGIG    K   +  A + +  R    C      ++    N Y+     DL
Sbjct: 37  KVVCITGGSSGIGLEIVKYLKQLNATIIVLGRT--DC------LISGVKNIYL-----DL 83

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGV-TKDGFETQLGVXXXXXXXXXXXX 144
           +    ++E V        H+ +L+NNAG +  P  + T  G++  +GV            
Sbjct: 84  SDLNKVKETVKEIHSVIDHIDILINNAGCVAIPSNIKTAQGYDITVGVNHIGHALLTLGI 143

Query: 145 XXXXKXXXXXXXXXXXXXXHQRGRIHKQDLN-MSENYDASAAYSQSKLANLLFARELGRR 203
               K                     +   N   E +D    Y  SKLAN LFA +L + 
Sbjct: 144 LDLIKKSQSPRIIVMSSLSAADWHQKEIPFNWKDEEWDPEIQYPASKLANSLFAIKLAQ- 202

Query: 204 LLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDP 263
            L   +  + V PGLV +   R+M+    + +F    + + F K P  G QT ++ AL P
Sbjct: 203 -LNPDIKCVHVHPGLVWSKFWRYMT---PIMKFIYTIILFLFSKTPLQGAQTAIYCALAP 258

Query: 264 KLKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
            ++  +G YY D    E +    D  +   LW
Sbjct: 259 NIE--SGKYYADCIPCEVNPLCNDQTVIDSLW 288


>UniRef50_Q5B8A4 Cluster: Putative uncharacterized protein; n=1;
           Emericella nidulans|Rep: Putative uncharacterized
           protein - Emericella nidulans (Aspergillus nidulans)
          Length = 291

 Score = 74.5 bits (175), Expect = 3e-12
 Identities = 63/233 (27%), Positives = 95/233 (40%), Gaps = 21/233 (9%)

Query: 47  KRGAKVFMACRDVKKCEEQRRDIV--LETNNKYVYCRPCDLASTASIREFVARFKGEEPH 104
           K    V++A R+ KK  E   D+      +   +     +L+  ++I++    F  +E  
Sbjct: 21  KNNGTVYLAARNAKKTAEVIADLKQRFPASRGRLDSISLNLSDLSTIKKSAEEFLAKETR 80

Query: 105 LHVLVNNAGVMEPPKG-VTKDGFETQLG---------VXXXXXXXXXXXXXXXXKXXXXX 154
           LHVL NNAGVM PP G  T  G+E QLG                                
Sbjct: 81  LHVLWNNAGVMFPPAGSTTSQGYELQLGTNNVGPHLFTKLLYPTLAATAKEAPKNTVRVV 140

Query: 155 XXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARELGRRLL--GTGVATI 212
                      +  I   +L+   N    + Y +SK   ++ A EL RR    G+G+ +I
Sbjct: 141 WVSSDAASWAPKPAIDFNNLDYRRNESDRSKYGRSKAGTVMQAVELARRARKDGSGIVSI 200

Query: 213 AVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKL 265
           A+DPG+ +T + R M  + S     I         KPEIG  T + A L P++
Sbjct: 201 ALDPGIANTGLQRDMGRLMSTMVKLI-------ANKPEIGAYTQLFAGLSPEI 246


>UniRef50_Q0C8N8 Cluster: Predicted protein; n=2;
           Trichocomaceae|Rep: Predicted protein - Aspergillus
           terreus (strain NIH 2624)
          Length = 334

 Score = 74.5 bits (175), Expect = 3e-12
 Identities = 78/294 (26%), Positives = 121/294 (41%), Gaps = 14/294 (4%)

Query: 15  PPYDRSVRADNRTIIITGAN-SGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLE 72
           P +D  V A+   ++ITGA+  G+G   A   A    A++ +  R  +K     ++I   
Sbjct: 37  PQFD--VVAEEAIVVITGASPGGLGANTALCLAAANPAEIVLLGRSEEKVSPVMKEISKI 94

Query: 73  TNNKYVYCRPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGV 132
           + +  V     DL S AS+R   A        + VL+NNAG+M     +T +  E+ LG 
Sbjct: 95  SPSTIVRFIKIDLMSCASVRTAAAEINASVSKIDVLINNAGIMGVKFSLTAENVESHLGA 154

Query: 133 XXXXXXXXXXXXXXXXKXXXXXXXXXXXXXX-HQRGRIHKQDLNMSEN--YDASAAYSQS 189
                           +               +Q   +   + N S+   YD   AY+QS
Sbjct: 155 NHIGHFLLTNLLVPKLEASGGGARIVNVSSAMYQLSPVMFDNYNFSDGKTYDPWIAYAQS 214

Query: 190 KLANLLFARELGRRLLGTGVATIAVDPGLVD-TDITRHMSMMK---SVTRFFIYPLFWPF 245
           K AN+LFA  L +RL    + + ++ PGL+  T ++  +         + F    L  P 
Sbjct: 215 KTANILFAVALAKRLEMKEIRSYSLHPGLIQTTGLSSGVDPAAWPIVGSMFESKKLVLPK 274

Query: 246 MKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSE 299
            K  + G  T + AALDP L      +  D    +    A D   A  LWR+SE
Sbjct: 275 EKGIDQGCATTLAAALDPALD---SSFLNDCNPEKVLDYASDSINADKLWRLSE 325


>UniRef50_Q7SEJ0 Cluster: Putative uncharacterized protein
           NCU09735.1; n=1; Neurospora crassa|Rep: Putative
           uncharacterized protein NCU09735.1 - Neurospora crassa
          Length = 302

 Score = 74.1 bits (174), Expect = 4e-12
 Identities = 83/294 (28%), Positives = 125/294 (42%), Gaps = 23/294 (7%)

Query: 27  TIIITG-ANSGIGKAAAKDFAKRG-AKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           +++ITG +  G+G   A   A    A + +  R + K +     I     +  V     D
Sbjct: 2   SVLITGPSEGGLGAETAISLAHANPALLILVGRSLNKIQPTIDAIHAVNPSIAVKFIAAD 61

Query: 85  LASTASIREFVARFKGEEP--HLHVLVNNAGVMEPPKGVTKDGFETQ-----LGVXXXXX 137
           L S  S+RE       +    H+ VL+NNA VM  P  +T DGFE Q     LG      
Sbjct: 62  LTSLNSVREAARSILDDASIAHIDVLINNAAVMACPYELTVDGFEMQFATAHLGHFVLTK 121

Query: 138 XXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS---ENYDASAAYSQSKLANL 194
                                     +  G I   D + +   E Y    AY Q+K AN+
Sbjct: 122 HILPKLRASAGAGKPQTRIINVSSLGNTLGGIRWDDPSYTKRPEEYKPWDAYGQAKTANV 181

Query: 195 LFARELGRRLLG-TGVATIAVDPGLVDTDITRHMS--MMKSVTRFFIYPLFWPFMKKPEI 251
           LF   L +RLL  TG+ + A+ PG + T + RHM+  +M+ +T+          +K  + 
Sbjct: 182 LFTVALNKRLLAKTGIRSYALHPGGIYTPLLRHMNDELMEEITQRVTKGEMQ--LKTVQQ 239

Query: 252 GGQTVVHAALDPKLKDCAGD--YYVDMK-KAEP---SQEAQDFELAQWLWRVSE 299
           G  T + AALDP+L+    D  +  D +   +P   +  A D E A+ LW +SE
Sbjct: 240 GCATTLRAALDPELEKAGEDGVFLSDCQFTKDPELVAPRALDEEDAERLWGLSE 293


>UniRef50_Q4WAX4 Cluster: Short-chain dehydrogenase, putative; n=11;
           Pezizomycotina|Rep: Short-chain dehydrogenase, putative
           - Aspergillus fumigatus (Sartorya fumigata)
          Length = 341

 Score = 74.1 bits (174), Expect = 4e-12
 Identities = 80/309 (25%), Positives = 125/309 (40%), Gaps = 36/309 (11%)

Query: 26  RTIIITGANSG-IGKAAAKDFAKRGAK-VFMACRDVKKCEEQRRDIVLETNNKYVYCRPC 83
           + I+ TG +SG +G    +  AK   + + +A R+  K  +   +I     +  V     
Sbjct: 25  KVILTTGVSSGSLGGFFVQSIAKAKPEWLILAARNADKLAQMAAEIAKAQPDVKVRTLKV 84

Query: 84  DLASTASIREFVARFKG--EEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXX 141
           DL S  S+R+  A      + P + VLVNNAG+M     ++ DGFE+ L           
Sbjct: 85  DLGSLESVRDAAAHVNSWDDVPVIDVLVNNAGIMAVDYQLSPDGFESHLATNHLGPFLFT 144

Query: 142 XXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMS----------------ENYDASAA 185
                                 H+       D N                  + Y+   A
Sbjct: 145 NLIMKKIVAAKEPRIVVVSSDGHRLNPFRFDDYNFDTYLRKPGTLTVTTQDGKTYNRWYA 204

Query: 186 YSQSKLANLLFARELGRRL-LGTGVATIAVDPGLVDTDITRHMSM------MKSVTRFFI 238
           Y QSK AN+LFA  L ++L +   +   ++ PG++ T++  H+        +++  +   
Sbjct: 205 YGQSKTANMLFAISLAQKLGVKYNLQAFSLHPGIIWTNLGNHLDWNIEFGELRNADKSLG 264

Query: 239 YPLFWP-FMKKP-EIGGQTVVHAALDPKLKDCAGDYYVDMKKAEP------SQEAQDFEL 290
               W  F  KP E G  T ++AA DP LK   G Y +D   A+P      S     FE 
Sbjct: 265 NREGWKDFDAKPLERGAATHIYAAFDPSLKANNGAYLLDCHVADPVVDTVKSWATSSFE- 323

Query: 291 AQWLWRVSE 299
           A+ LWR+SE
Sbjct: 324 AERLWRLSE 332


>UniRef50_Q4S7K6 Cluster: Chromosome 13 SCAF14715, whole genome
           shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 13
           SCAF14715, whole genome shotgun sequence - Tetraodon
           nigroviridis (Green puffer)
          Length = 399

 Score = 73.7 bits (173), Expect = 6e-12
 Identities = 56/174 (32%), Positives = 80/174 (45%), Gaps = 14/174 (8%)

Query: 83  CDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXX 142
           CDLAS  S+REF   FK     LH+LV NA V   P  +T+DG E+   +          
Sbjct: 231 CDLASLRSVREFADSFKSRNLPLHILVCNAAVCTQPWSLTEDGLESTFQICHLGHFLLVQ 290

Query: 143 XXXXXXKXXXXXXXXXXXXXXHQ----RGRIHKQDLNM----SENYDASAAYSQSKLANL 194
                 +              H+    R    K DL++     ++Y +  AY+++KL N+
Sbjct: 291 CLQDVLRRSAPARVVVVSSESHRFTDLRDSGGKVDLDLLSPAKQHYWSMLAYNRAKLCNI 350

Query: 195 LFARELGRRLLGTGVATIAVDPG-LVDTDITRHMSMMKSVTRFFIYPLFWPFMK 247
           LF+ EL RRL   GV + AV PG ++ T I R   +M      F++ L  PF K
Sbjct: 351 LFSNELHRRLSPYGVTSNAVHPGNMMYTSIHRSWWLMT-----FLFTLARPFTK 399



 Score = 41.9 bits (94), Expect = 0.021
 Identities = 17/40 (42%), Positives = 26/40 (65%)

Query: 25  NRTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEE 64
           ++ ++ITG NSGIG   A+  A  GA V MACR++ +  +
Sbjct: 121 DKVVLITGGNSGIGFETARSLALHGAHVIMACRNLSRANK 160


>UniRef50_A0Y9Z7 Cluster: Oxidoreductase; n=1; marine gamma
           proteobacterium HTCC2143|Rep: Oxidoreductase - marine
           gamma proteobacterium HTCC2143
          Length = 339

 Score = 73.7 bits (173), Expect = 6e-12
 Identities = 74/285 (25%), Positives = 111/285 (38%), Gaps = 16/285 (5%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +T ++TG NSGIG    +  A RGA V    R ++K +     I   +          +L
Sbjct: 61  KTAVVTGCNSGIGYETMRVLALRGAHVIGTGRTLEKAQ-----IACASVEGITTPVALEL 115

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFE-----TQLGVXXXXXXXX 140
           +   S  +   R K     + +++ NAG+    +    DG E       LG         
Sbjct: 116 SDFQSAVDCANRIKAMNTPIDIVICNAGINTFGELELIDGIERIFRVNHLGHFVLINNLL 175

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAREL 200
                                     G I   +L   + +DA  AY +SKLAN LF+ +L
Sbjct: 176 PALASANAGRIVHVGSVSGYVQAPAVG-IDFDNLRGEKIFDAGEAYGRSKLANALFSLQL 234

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAA 260
            + L  T   +  + PGLV T+I R           ++ PL   F K P  G  T V+ A
Sbjct: 235 SKNLADTTTTSNVIHPGLVLTNIARTAPAFLRKGFEWVGPL---FAKTPAQGAATQVYVA 291

Query: 261 LDPKLKDCAGDYYVDMKKAEPSQEAQDFE--LAQWLWRVSEAWTK 303
             P L+  +G Y+ D      S +   F+  +A  LW VS   T+
Sbjct: 292 THPSLEGISGAYFEDCNPVTISGDHHMFDEAMADKLWSVSMEMTR 336


>UniRef50_A6QSP2 Cluster: Predicted protein; n=1; Ajellomyces
           capsulatus NAm1|Rep: Predicted protein - Ajellomyces
           capsulatus NAm1
          Length = 338

 Score = 73.7 bits (173), Expect = 6e-12
 Identities = 40/124 (32%), Positives = 70/124 (56%), Gaps = 8/124 (6%)

Query: 178 ENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHM--SMMKSVTR 235
           ++YD+  AY QSK ANLLF   L + L   G+ ++ + PG++DT++ R+M   +M ++  
Sbjct: 212 KSYDSMIAYGQSKTANLLFTTYLAKHLASEGITSLTLHPGVIDTELGRYMPVELMGAIKE 271

Query: 236 FFIYPLFWPFMKKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLW 295
                   P  K  + G  T V AA DP L+  +G + +D + + P+  + + E A+ LW
Sbjct: 272 LV------PNWKTQDEGAATSVVAAFDPALQAHSGSFLMDCQISAPAAYSVNEESAEKLW 325

Query: 296 RVSE 299
           +++E
Sbjct: 326 KLTE 329



 Score = 63.3 bits (147), Expect = 8e-09
 Identities = 36/107 (33%), Positives = 61/107 (57%), Gaps = 3/107 (2%)

Query: 27  TIIITGAN-SGIGKAAAKDFAK-RGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCD 84
           T+++TG N  G+G A     A+ R A++ +  R  +K +E  +D+ +      V     D
Sbjct: 28  TVLVTGVNPKGLGGAVVAAIAQYRPARIIITGRSQEKLDEVAKDLDISFPKVPVTAATVD 87

Query: 85  LASTASIREFVARFKGEEPHLHVLVNNAGVME-PPKGVTKDGFETQL 130
           LAS  S+R+  A+ KGE   + V++NNAG+M  P + ++++GFE  L
Sbjct: 88  LASLRSVRKAAAKIKGEVDSIDVVLNNAGIMALPERELSENGFEMHL 134


>UniRef50_Q54NY5 Cluster: Putative uncharacterized protein; n=1;
           Dictyostelium discoideum AX4|Rep: Putative
           uncharacterized protein - Dictyostelium discoideum AX4
          Length = 329

 Score = 73.3 bits (172), Expect = 7e-12
 Identities = 76/292 (26%), Positives = 125/292 (42%), Gaps = 29/292 (9%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETN--NKYVYCRPC 83
           + +IITG+N+G+GK  AK   K GA +  ACR+  K +E  +++   +N  N  +     
Sbjct: 39  KVVIITGSNAGLGKEIAKKIGKLGAHIIFACRNELKAKEAIKEVFEFSNCENDKLEFMKL 98

Query: 84  DLASTASIREFVARFKG-EEPHLHVLVNNAGVM---EPPK---GVTKDG---FETQLGVX 133
           DL S  SI+EFV +F+  ++    +L+NNAG+M   E  K    +TK+G   F TQ  + 
Sbjct: 99  DLLSLGSIKEFVNQFQNIKKLKCDILINNAGIMWLWEDKKWNNPITKNGGNQFNTQF-LA 157

Query: 134 XXXXXXXXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLAN 193
                                         H  G    ++L    +Y     Y QSKLA 
Sbjct: 158 NYLGHFLLTQLLFKNLMENQARILNISSSVHSLGGFSLENLINDTSY-TFQTYCQSKLAQ 216

Query: 194 LLFARELGRRLLG------TGVATI-AVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFM 246
           +     L   +        T  ATI A+ PG+  ++I            F +  L+    
Sbjct: 217 IYSTYYLDSLINSVENENITNKATINAIHPGIFASEIVN--------LPFPLDRLYHKIF 268

Query: 247 KKPEIGGQTVVHAALDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVS 298
           K  E   + +V  A++ + +  +G Y+ D K    S  + + E+ + L++ S
Sbjct: 269 KSAEYCARAIVKCAIENQYQSISGKYFDDTKIINSSSLSYNKEIGKQLYQQS 320


>UniRef50_Q6C9P4 Cluster: Yarrowia lipolytica chromosome D of strain
           CLIB122 of Yarrowia lipolytica; n=5; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome D of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 322

 Score = 73.3 bits (172), Expect = 7e-12
 Identities = 60/228 (26%), Positives = 95/228 (41%), Gaps = 17/228 (7%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           +T +ITG +SG+G  A K    +GAKV +  R+ +K ++  +++    + K+ +    DL
Sbjct: 34  KTYVITGGHSGVGLEATKLLIGKGAKVIIVGRNKEKAQDVLKEL---PDGKFDFAE-ADL 89

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXXXXXXX 145
           A   +I           P +H ++ NAGVM PP   T  G E Q G              
Sbjct: 90  ADLTTISTAGDYITKNYPEIHGVILNAGVMTPPYSKTAQGHELQWGTNVVGHQAIMKYLT 149

Query: 146 -XXXKXXXXX---------XXXXXXXXXHQRGRIHKQDLN--MSENYDASAAYSQSKLAN 193
               K                          G I+  D+N    EN      YSQSK+ N
Sbjct: 150 PIVIKTAKTSPPGTVRLVWVSSSAVVISGLPGGINFDDINYEKEENPSPHVLYSQSKIGN 209

Query: 194 LLFARELGRRLLGTGVATIAVDPGLVDTDITRHMS-MMKSVTRFFIYP 240
              A    +    +GV +++VDPG + +++ RH S  +K    + +YP
Sbjct: 210 AYQAYLWSKNHPDSGVISVSVDPGNLKSNLQRHSSEFLKKAFNYVLYP 257


>UniRef50_A3CQN6 Cluster: Dehydrogenase, eukaryotic-like, putative;
           n=3; Lactobacillales|Rep: Dehydrogenase,
           eukaryotic-like, putative - Streptococcus sanguinis
           (strain SK36)
          Length = 284

 Score = 72.9 bits (171), Expect = 1e-11
 Identities = 62/226 (27%), Positives = 102/226 (45%), Gaps = 11/226 (4%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + +IITG NSGIG  AAK  A++G  V + CR  +  E+    I  +T N +V     DL
Sbjct: 2   KKVIITGGNSGIGYQAAKQLAEKGWSVTLFCRRKEAAEQACEKIRQQTGNSHVDYILVDL 61

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVME---PPKGVTKDGFETQLG---VXXXXXXX 139
           +   S+R+ V ++  +E  L VL+NNA   +       +TKDG E Q     V       
Sbjct: 62  SEMKSVRKAVEQYIQKEETLDVLINNAADFDLSIKKPILTKDGLEKQFATNVVAPFLLSA 121

Query: 140 XXXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFARE 199
                    +              +   ++  ++L+  ++Y  +  Y Q+KLA L+ +  
Sbjct: 122 LLKGLLEKSESGRIVNISSQGLVLYPFMKLDFENLSGQKHYSPAKTYYQNKLALLMLSLY 181

Query: 200 LGRRLLGTGVATIAVDPGLVDTDITRHMSM-MKSV----TRFFIYP 240
           + ++  G  +  I V    VD     H+S+ MK++    +RF I P
Sbjct: 182 MRKQSKGIKIQAIRVTIVKVDMRRYDHLSVFMKNLYKIKSRFSISP 227


>UniRef50_A2R6G5 Cluster: Contig An15c0250, complete genome; n=1;
           Aspergillus niger|Rep: Contig An15c0250, complete genome
           - Aspergillus niger
          Length = 319

 Score = 72.9 bits (171), Expect = 1e-11
 Identities = 36/94 (38%), Positives = 59/94 (62%), Gaps = 2/94 (2%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCR--PC 83
           + +I+TG ++G+G   + + A+ GA+V++A R   + E  RRDI+ E + + V  R    
Sbjct: 17  KVVIVTGGHTGLGFGTSIELARHGARVYIASRSHTRFEHARRDIIAECSEREVDVRFLNL 76

Query: 84  DLASTASIREFVARFKGEEPHLHVLVNNAGVMEP 117
           DL+S +S+R    +F  +E  LH+LVNNAGV +P
Sbjct: 77  DLSSISSVRHAAEQFIRQESRLHLLVNNAGVGDP 110



 Score = 54.4 bits (125), Expect = 4e-06
 Identities = 44/140 (31%), Positives = 71/140 (50%), Gaps = 10/140 (7%)

Query: 173 DLNMSENYDASAAYSQSKLANLLFARELGRRLLGTGVATIAVDPGLVDTDITRHMSMMKS 232
           D+NM   +   A Y  SKLAN+L +REL +R     +  ++V PG V T +         
Sbjct: 184 DMNMKA-FSVWARYGHSKLANILHSRELAKRY--PDILALSVHPGTVKTGLAAGPISSTP 240

Query: 233 VTRFFIYPLFWPFMKKPEIGGQTVVHAALDPKLK-DC-AGDYYVDM-KKAEPSQEAQDFE 289
           + R  I PL       P  G  +++ AA+ P+LK +C  G Y + + + + PS+   D +
Sbjct: 241 LYR-LIKPLVELGAPGPRKGAASILFAAVSPQLKLECHNGAYLLPIGRLSAPSKAGSDAK 299

Query: 290 LAQ--WLWRVSE-AWTKLDE 306
           +A+  W W V+  +  K+DE
Sbjct: 300 MAEELWEWTVNALSHVKVDE 319


>UniRef50_A1ZQT0 Cluster: Dehydrogenase/ reductase 1; n=1;
           Microscilla marina ATCC 23134|Rep: Dehydrogenase/
           reductase 1 - Microscilla marina ATCC 23134
          Length = 338

 Score = 72.1 bits (169), Expect = 2e-11
 Identities = 37/105 (35%), Positives = 55/105 (52%)

Query: 26  RTIIITGANSGIGKAAAKDFAKRGAKVFMACRDVKKCEEQRRDIVLETNNKYVYCRPCDL 85
           + + ITG  SG G   A++ AK+GAKV +  R  ++ E+  + +  E  N       CDL
Sbjct: 36  KVVAITGTTSGTGFVCAREVAKKGAKVLLLNRQSERAEQALKQLQNEVPNGKFEAVTCDL 95

Query: 86  ASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQL 130
               S+R  +   K +   + VLVNNAGVM      TKDG++ Q+
Sbjct: 96  QDFDSVRNAIDTIKAKHEVIDVLVNNAGVMALEDKATKDGYDVQM 140


>UniRef50_A0VWL5 Cluster: Oxidoreductase, short chain
           dehydrogenase/reductase family; n=1; Dinoroseobacter
           shibae DFL 12|Rep: Oxidoreductase, short chain
           dehydrogenase/reductase family - Dinoroseobacter shibae
           DFL 12
          Length = 252

 Score = 72.1 bits (169), Expect = 2e-11
 Identities = 59/222 (26%), Positives = 83/222 (37%), Gaps = 5/222 (2%)

Query: 81  RPCDLASTASIREFVARFKGEEPHLHVLVNNAGVMEPPKGVTKDGFETQLGVXXXXXXXX 140
           RP DL S A IR   A      P + +L+NNAG   P + +T+DG E  L +        
Sbjct: 25  RP-DLMSFARIRTLAADLATRFPRIDILINNAGANFPTRRLTEDGVEATLAINHFAPFLL 83

Query: 141 XXXXXXXXKXXXXXXXXXXXXXXHQRGRIHKQDLNMSENYDASAAYSQSKLANLLFAREL 200
                   K              H+R      DL M   Y    AY ++K  NL     +
Sbjct: 84  TNLLAGPLKAAPAARIIMVNSDWHRRSLPDMHDLQMESGYRTGEAYCRAKFMNLQITYAM 143

Query: 201 GRRLLGTGVATIAVDPGLVDTDITRHMSMMKSVTRFFIYPLFWPFMKKPEIGGQTVVHAA 260
              L GT V   A+ PG+V T I+   +                 M  PE     +   A
Sbjct: 144 AALLDGTNVTVNAIHPGVVRTGISTRNTDGAPQVPAQARERAQQRMISPEFSAVYLASLA 203

Query: 261 LDPKLKDCAGDYYVDMKKAEPSQEAQDFELAQWLWRVSEAWT 302
             P  +  +G  Y+D  + + S EA   E   W W++ E W+
Sbjct: 204 TAPDYEGQSG-LYLDTDEIKQSHEATYDE--DWAWQIWE-WS 241


>UniRef50_Q6CA42 Cluster: Yarrowia lipolytica chromosome D of strain
           CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
           lipolytica|Rep: Yarrowia lipolytica chromosome D of
           strain CLIB122 of Yarrowia lipolytica - Yarrowia
           lipolytica (Candida lipolytica)
          Length = 440

 Score = 71.7 bits (168), Expect = 2e-11
 Identities = 73/332 (21%), Positives = 128/332 (38%), Gaps = 29/332 (8%)

Query: 9   RDYYSGPPYDRSVRADNRTIIITGANSGIGKAAAKDFAKRGAKVFMACRD-VKKCEEQRR 67
           + Y+ G           R +I+TG  SG+G   A++ A++GA++ +  R+      E   
Sbjct: 37  KTYFGGSTNTWQRDMHGRVVIMTGGTSGVGAEIARELAQKGAQLILLVREHTTYAAEFVD 96

Query: 68  DIVLETNNKYVYCRPCDLASTASIREFVARFKGEEP--HLHVLVNNAGVMEPP---KGVT 122
           D+   + N+ VY   CDL    S+R+F  ++   +P   L  ++  A    PP   +  +
Sbjct: 97  DLRAASGNELVYMETCDLNDLHSVRKFATKWLDNQPPRRLDTVICCAATATPPSVERKYS 156

Query: 123 KDGFETQLGVXXXXXXXXXXXXXXXXKX---XXXXXXXXXXXXXHQRGRIHKQDLNMSE- 178
           +DG E  L V                K                 H    +   DL  +  
Sbjct: 157 RDGIEEMLQVNYLAHYHLLTLLEPALKVQPPDRDVRIVLTSCVAHVMADLDFSDLQFTRR 216

Query: 179 ---NYDASAAYSQSKLANLLFARELGRRLLG--------TGVATIAVDPGLVDTDITRHM 227
               Y    A+  SKL   +F  E  RRL            V  +  DPG++ +   +  
Sbjct: 217 KYPTYSPWRAFGASKLLLNMFGYEYQRRLAAYERPDKAPCNVRVVMADPGMMRSPSFKRF 276

Query: 228 SMMKSVTRFFIYPLFWPF----MKKPEIGGQTVVHAA----LDPKLKDCAGDYYVDMKKA 279
               SV    +Y +FWPF    +K  + G Q++++      L   +++       D++  
Sbjct: 277 ITCGSVLLLLLYLVFWPFWWLVLKTSKQGMQSILYGVFCGELPAPIEEAVYIQECDVRSH 336

Query: 280 EPSQEAQDFELAQWLWRVSEAWTKLDEHKQAI 311
               E  D EL + ++  ++   ++ E K AI
Sbjct: 337 MARAEMNDKELQKEVFDKTKLMVEVIEKKSAI 368


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.320    0.135    0.407 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 318,683,948
Number of Sequences: 1657284
Number of extensions: 11594101
Number of successful extensions: 35606
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 1881
Number of HSP's successfully gapped in prelim test: 1551
Number of HSP's that attempted gapping in prelim test: 30585
Number of HSP's gapped (non-prelim): 4858
length of query: 317
length of database: 575,637,011
effective HSP length: 101
effective length of query: 216
effective length of database: 408,251,327
effective search space: 88182286632
effective search space used: 88182286632
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.8 bits)
S2: 72 (33.1 bits)

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